A0A044T183_ONCVO Loading...

G-protein coupled receptors family 1 profile domain-containing protein

AlphaFold DB , UniProt , Accession A0A044T183, Species ONCVO (Onchocerca volvulus), Gene n/a, Length 441 aa.

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	41.5	Very low	51.9	Low	213 Å²	213	109 Å²	109	100%	1.049	54%	0.54	S	S	*	.				0	-47	0	-96.1	170.4	62.4	0	0	114.1	R4 S5	M1-R4 WeakPolarHBondContact O-CB 3.41Å; M1-R4 PolarHBondContact O-N 2.94Å; M1-S5 PolarHBondContact O-N 3.23Å
2	I	35.8	Very low	52.5	Low	52 Å²	52	108.3 Å²	108.3	27%	0.267	53%	0.532	S	S	.	.	H	α-helix	trans	-68.4	-42.5	-176	-65.2	163.9	0	0	0	114.1	R4 S5 F6 F313 W352	I2-R4 PolarHBondContact O-N 3.45Å; I2-S5 WeakPolarHBondContact CA-OG 3.46Å; I2-S5 CarbonylContact O-C 2.89Å; I2-S5 WeakPolarHBondContact O-CA 3.45Å; I2-S5 WeakPolarHBondContact O-CB 3.33Å; I2-S5 PolarHBondContact O-N 2.9Å; I2-S5 PolarHBondContact O-OG 2.92Å; I2-F6 HydrophobicContact CG2-CD2 3.82Å; I2-F6 HydrophobicContact CG2-CE2 4.35Å; I2-F6 PolarHBondContact O-N 3.19Å; I2-F313 HydrophobicContact CD1-CD1 4.46Å; I2-F313 HydrophobicContact CD1-CE1 3.8Å; I2-W352 HydrophobicContact CD1-CH2 3.24Å; I2-W352 HydrophobicContact CD1-CZ2 3.85Å; I2-W352 HydrophobicContact CD1-CZ3 4.18Å; I2-W352 HydrophobicContact CG1-CH2 4.29Å
3	A	49.7	Very low	53	Low	84 Å²	84	102.5 Å²	102.5	69%	0.694	50%	0.504	S	S	*	.	H	α-helix	trans	-56.4	-41.3	175.9	0	0	0	0	0	110.8	F6 Y7	A3-F6 PolarHBondContact O-N 3.05Å; A3-Y7 WeakPolarHBondContact O-CB 3.48Å; A3-Y7 PolarHBondContact O-N 3.28Å
4	R	48.1	Very low	53.7	Low	206 Å²	206	101.8 Å²	101.8	78%	0.777	50%	0.502	S	S	*	.	H	α-helix	trans	-62.8	-42	169.6	-81	-174	175.9	-179.5	-1.5	112.2	M1 I2 Y7 M8	M1-R4 WeakPolarHBondContact O-CB 3.41Å; M1-R4 PolarHBondContact O-N 2.94Å; I2-R4 PolarHBondContact O-N 3.45Å; R4-Y7 PolarHBondContact O-N 3Å; R4-M8 WeakPolarHBondContact O-CB 3.17Å; R4-M8 WeakPolarHBondContact O-CG 3.46Å; R4-M8 PolarHBondContact O-N 3.41Å
5	S	48.7	Very low	54	Low	49 Å²	49	102.4 Å²	102.4	34%	0.343	51%	0.507	S	S	.	.	H	α-helix	trans	-62.5	-43.1	176.5	81	0	0	0	0	112.4	M1 I2 Y7 M8 I9	M1-S5 PolarHBondContact O-N 3.23Å; I2-S5 WeakPolarHBondContact CA-OG 3.46Å; I2-S5 CarbonylContact O-C 2.89Å; I2-S5 WeakPolarHBondContact O-CA 3.45Å; I2-S5 WeakPolarHBondContact O-CB 3.33Å; I2-S5 PolarHBondContact O-N 2.9Å; I2-S5 PolarHBondContact O-OG 2.92Å; S5-Y7 VanDerWaalsContact C-N 3.35Å; S5-M8 PolarHBondContact O-N 3.03Å; S5-I9 WeakPolarHBondContact O-CB 3.44Å; S5-I9 VanDerWaalsContact O-CD1 3.24Å; S5-I9 WeakPolarHBondContact O-CD1 3.49Å; S5-I9 WeakPolarHBondContact O-CG1 3.35Å; S5-I9 PolarHBondContact O-N 3.16Å
6	F	53.3	Low	54.1	Low	104 Å²	104	99.2 Å²	99.2	46%	0.456	49%	0.493	S	S	.	.	H	α-helix	trans	-65.5	-39.7	176.9	-106.3	-79.7	0	0	0	111	I2 A3 I9 V10	I2-F6 HydrophobicContact CG2-CD2 3.82Å; I2-F6 HydrophobicContact CG2-CE2 4.35Å; I2-F6 PolarHBondContact O-N 3.19Å; A3-F6 PolarHBondContact O-N 3.05Å; F6-I9 PolarHBondContact O-N 3.02Å; F6-V10 WeakPolarHBondContact O-CB 3.27Å; F6-V10 WeakPolarHBondContact O-CG2 3.41Å; F6-V10 PolarHBondContact O-N 2.86Å
7	Y	57.6	Low	54.3	Low	179 Å²	179	95.6 Å²	95.6	70%	0.702	48%	0.482	S	S	*	.	H	α-helix	trans	-61.8	-44.6	173.1	-133.7	-85.1	0	0	0	111.4	A3 R4 S5 I9 V10 L11	A3-Y7 WeakPolarHBondContact O-CB 3.48Å; A3-Y7 PolarHBondContact O-N 3.28Å; R4-Y7 PolarHBondContact O-N 3Å; S5-Y7 VanDerWaalsContact C-N 3.35Å; Y7-I9 VanDerWaalsContact C-N 3.28Å; Y7-I9 PolarHBondContact O-N 3.35Å; Y7-V10 PolarHBondContact O-N 3.31Å; Y7-L11 WeakPolarHBondContact O-CB 3.49Å; Y7-L11 PolarHBondContact O-N 3.35Å
8	M	54.8	Low	54.3	Low	114 Å²	114	96.1 Å²	96.1	56%	0.562	49%	0.491	S	S	*	.	H	α-helix	trans	-63.3	-34.4	175.4	-66.6	-67.8	-78.5	0	0	111.7	R4 S5 F12	R4-M8 WeakPolarHBondContact O-CB 3.17Å; R4-M8 WeakPolarHBondContact O-CG 3.46Å; R4-M8 PolarHBondContact O-N 3.41Å; S5-M8 PolarHBondContact O-N 3.03Å; M8-F12 WeakPolarHBondContact O-CB 3.44Å; M8-F12 PolarHBondContact O-N 3.45Å
9	I	57.3	Low	54.2	Low	39 Å²	39	97.1 Å²	97.1	20%	0.2	51%	0.506	C	S	.	.	H	α-helix	trans	-70.3	-49.8	176.8	-68.5	154.4	0	0	0	111	S5 F6 Y7 L11 F12 L13 F386	S5-I9 WeakPolarHBondContact O-CB 3.44Å; S5-I9 VanDerWaalsContact O-CD1 3.24Å; S5-I9 WeakPolarHBondContact O-CD1 3.49Å; S5-I9 WeakPolarHBondContact O-CG1 3.35Å; S5-I9 PolarHBondContact O-N 3.16Å; F6-I9 PolarHBondContact O-N 3.02Å; Y7-I9 VanDerWaalsContact C-N 3.28Å; Y7-I9 PolarHBondContact O-N 3.35Å; I9-L11 VanDerWaalsContact C-N 3.26Å; I9-L11 PolarHBondContact O-N 3.4Å; I9-F12 PolarHBondContact O-N 3.39Å; I9-F12 VanDerWaalsContact O-N 3.14Å; I9-L13 HydrophobicContact CG2-CD1 4.15Å; I9-L13 WeakPolarHBondContact O-CG 3.46Å; I9-L13 PolarHBondContact O-N 3.48Å; I9-F386 HydrophobicContact CD1-CD2 4Å; I9-F386 HydrophobicContact CD1-CE2 3.4Å; I9-F386 VanDerWaalsContact CD1-CE2 3.4Å; I9-F386 HydrophobicContact CD1-CZ 4.32Å; I9-F386 HydrophobicContact CG1-CD2 4.09Å; I9-F386 HydrophobicContact CG1-CE2 4.01Å; I9-F386 HydrophobicContact CG2-CD2 3.97Å; I9-F386 HydrophobicContact CG2-CE2 4.13Å
10	V	62.4	Low	54.1	Low	71 Å²	71	95.5 Å²	95.5	43%	0.43	50%	0.496	S	S	.	.	H	α-helix	trans	-60.8	-40.8	175.8	171.1	0	0	0	0	109.7	F6 Y7 F12 L13 I14	F6-V10 WeakPolarHBondContact O-CB 3.27Å; F6-V10 WeakPolarHBondContact O-CG2 3.41Å; F6-V10 PolarHBondContact O-N 2.86Å; Y7-V10 PolarHBondContact O-N 3.31Å; V10-F12 PolarHBondContact O-N 3.12Å; V10-L13 PolarHBondContact O-N 3.21Å; V10-I14 HydrophobicContact CG1-CD1 3.53Å; V10-I14 HydrophobicContact CG1-CG1 4.2Å; V10-I14 WeakPolarHBondContact O-CB 3.2Å; V10-I14 WeakPolarHBondContact O-CG1 3.18Å; V10-I14 PolarHBondContact O-N 3.3Å
11	L	61.9	Low	53.9	Low	88 Å²	88	98.6 Å²	98.6	46%	0.461	51%	0.513	S	S	.	.	H	α-helix	trans	-61.4	-44.4	173.9	-165.2	76.1	0	0	0	111.1	Y7 I9 L13 I14 L15	Y7-L11 WeakPolarHBondContact O-CB 3.49Å; Y7-L11 PolarHBondContact O-N 3.35Å; I9-L11 VanDerWaalsContact C-N 3.26Å; I9-L11 PolarHBondContact O-N 3.4Å; L11-L13 PolarHBondContact O-N 3.45Å; L11-I14 PolarHBondContact O-N 3.18Å; L11-L15 VanDerWaalsContact O-CB 3.24Å; L11-L15 WeakPolarHBondContact O-CB 3.41Å; L11-L15 PolarHBondContact O-N 3.04Å
12	F	59	Low	54.4	Low	101 Å²	101	96 Å²	96	44%	0.443	50%	0.496	S	S	.	.	H	α-helix	trans	-64	-37.9	176.1	-111.3	-79.4	0	0	0	113.3	M8 I9 V10 N16 I41	M8-F12 WeakPolarHBondContact O-CB 3.44Å; M8-F12 PolarHBondContact O-N 3.45Å; I9-F12 PolarHBondContact O-N 3.39Å; I9-F12 VanDerWaalsContact O-N 3.14Å; V10-F12 PolarHBondContact O-N 3.12Å; F12-N16 PolarHBondContact O-N 3.32Å; F12-N16 PolarHBondContact O-ND2 2.85Å; F12-I41 HydrophobicContact CE1-CD1 4.15Å; F12-I41 HydrophobicContact CE1-CG2 4.13Å; F12-I41 HydrophobicContact CZ-CG2 4.41Å
13	L	58.7	Low	55.2	Low	33 Å²	33	101.9 Å²	101.9	17%	0.173	53%	0.528	C	S	.	.	H	α-helix	trans	-68.1	-45.6	176.1	-70.3	173.6	0	0	0	110.9	I9 V10 L11 A17 P382	I9-L13 HydrophobicContact CG2-CD1 4.15Å; I9-L13 WeakPolarHBondContact O-CG 3.46Å; I9-L13 PolarHBondContact O-N 3.48Å; V10-L13 PolarHBondContact O-N 3.21Å; L11-L13 PolarHBondContact O-N 3.45Å; L13-A17 WeakPolarHBondContact O-CB 3.38Å; L13-A17 PolarHBondContact O-N 2.74Å; L13-P382 HydrophobicContact CD2-CB 3.48Å; L13-P382 VanDerWaalsContact CD2-CB 3.48Å
14	I	62.9	Low	55.5	Low	92 Å²	92	102 Å²	102	47%	0.472	52%	0.521	S	S	.	.	H	α-helix	trans	-63.2	-47.1	177.2	-69	169.5	0	0	0	110.3	V10 L11 N16 A17 T18	V10-I14 HydrophobicContact CG1-CD1 3.53Å; V10-I14 HydrophobicContact CG1-CG1 4.2Å; V10-I14 WeakPolarHBondContact O-CB 3.2Å; V10-I14 WeakPolarHBondContact O-CG1 3.18Å; V10-I14 PolarHBondContact O-N 3.3Å; L11-I14 PolarHBondContact O-N 3.18Å; I14-N16 VanDerWaalsContact C-N 3.32Å; I14-N16 PolarHBondContact O-N 3.11Å; I14-A17 PolarHBondContact O-N 3.38Å; I14-T18 PolarHBondContact O-N 3.49Å; I14-T18 PolarHBondContact O-OG1 3.14Å
15	L	58	Low	56.1	Low	111 Å²	111	99.7 Å²	99.7	58%	0.581	53%	0.529	S	S	*	.	H	α-helix	trans	-62.2	-39.5	-176.5	-148.4	93.1	0	0	0	111.8	L11 T18	L11-L15 VanDerWaalsContact O-CB 3.24Å; L11-L15 WeakPolarHBondContact O-CB 3.41Å; L11-L15 PolarHBondContact O-N 3.04Å; L15-T18 PolarHBondContact O-OG1 2.96Å; L15-T18 VanDerWaalsContact O-OG1 3.13Å
16	N	55.8	Low	56.8	Low	51 Å²	51	102.5 Å²	102.5	27%	0.273	54%	0.541	S	S	.	.	H	α-helix	trans	-70	-42.5	175.5	-86.3	-39.3	0	0	0	112	F12 I14 T18 C19 P382	F12-N16 PolarHBondContact O-N 3.32Å; F12-N16 PolarHBondContact O-ND2 2.85Å; I14-N16 VanDerWaalsContact C-N 3.32Å; I14-N16 PolarHBondContact O-N 3.11Å; N16-T18 VanDerWaalsContact C-N 3.34Å; N16-T18 PolarHBondContact O-N 3.06Å; N16-C19 PolarHBondContact O-N 2.99Å; N16-P382 HydrophobicContact CB-CG 4.2Å
17	A	56.8	Low	57.7	Low	38 Å²	38	104 Å²	104	31%	0.314	55%	0.547	S	S	.	.	H	α-helix	trans	-63	-39.3	-179.6	0	0	0	0	0	112	L13 I14 C19	L13-A17 WeakPolarHBondContact O-CB 3.38Å; L13-A17 PolarHBondContact O-N 2.74Å; I14-A17 PolarHBondContact O-N 3.38Å; A17-C19 PolarHBondContact O-N 3.45Å
18	T	55.6	Low	58.5	Low	105 Å²	105	98 Å²	98	64%	0.644	52%	0.524	S	S	*	.	T	Hydrogen-bonded Turn	trans	-70.2	-13.9	-179.9	43.5	0	0	0	0	114.9	I14 L15 N16	I14-T18 PolarHBondContact O-N 3.49Å; I14-T18 PolarHBondContact O-OG1 3.14Å; L15-T18 PolarHBondContact O-OG1 2.96Å; L15-T18 VanDerWaalsContact O-OG1 3.13Å; N16-T18 VanDerWaalsContact C-N 3.34Å; N16-T18 PolarHBondContact O-N 3.06Å
19	C	52.6	Low	59.8	Low	114 Å²	114	94 Å²	94	77%	0.77	51%	0.505	S	S	*	.	T	Hydrogen-bonded Turn	trans	-94.4	-0.1	-177	-82.3	0	0	0	0	114.5	N16 A17	N16-C19 PolarHBondContact O-N 2.99Å; A17-C19 PolarHBondContact O-N 3.45Å
20	Q	51.1	Low	61.1	Low	65 Å²	65	92.2 Å²	92.2	30%	0.304	50%	0.496	S	S	.	.			trans	-117.2	58.6	-168.7	-153.2	162.1	9.9	0	0	113.4	K22 H35	Q20-K22 PolarHBondContact O-N 3.05Å; Q20-K22 VanDerWaalsContact O-N 3.09Å; Q20-H35 PolarHBondContact NE2-NE2 3.33Å
21	D	50.7	Low	62	Low	162 Å²	162	93.9 Å²	93.9	87%	0.866	50%	0.495	S	S	*	.			trans	-72.3	95	161.7	-93.8	-24.1	0	0	0	109.1
22	K	51.6	Low	63	Low	158 Å²	158	92.7 Å²	92.7	69%	0.687	49%	0.489	S	S	*	.			trans	-163.5	122.2	159.4	-117.5	166.9	-175.1	-179.1	0	114.5	Q20 T24	Q20-K22 PolarHBondContact O-N 3.05Å; Q20-K22 VanDerWaalsContact O-N 3.09Å; K22-T24 PolarHBondContact O-N 3.22Å
23	N	53.3	Low	64	Low	175 Å²	175	95.9 Å²	95.9	94%	0.936	51%	0.505	S	S	*	.			trans	-65.8	86.8	163.9	-83.6	-22.8	0	0	0	110.6
24	T	55.2	Low	65.2	Low	88 Å²	88	100.9 Å²	100.9	54%	0.54	53%	0.527	S	S	.	.			trans	-133	122.4	159.8	42.7	0	0	0	0	109.4	K22 N26	K22-T24 PolarHBondContact O-N 3.22Å; T24-N26 PolarHBondContact O-N 3.47Å
25	T	60.9	Low	66.3	Low	157 Å²	157	97.5 Å²	97.5	96%	0.963	51%	0.509	S	S	*	.			trans	-64.6	26.3	171.6	-18.4	0	0	0	0	112.7
26	N	64	Low	67.8	Low	108 Å²	108	97.9 Å²	97.9	58%	0.578	51%	0.507	S	S	*	.	P	Polyproline II helix	trans	-88.1	126.7	-176.4	-81.8	-10.3	0	0	0	109.2	T24 F28	T24-N26 PolarHBondContact O-N 3.47Å; N26-F28 PolarHBondContact O-N 3.33Å; N26-F28 VanDerWaalsContact O-N 3.15Å
27	K	71.8	Confident	69.3	Low	135 Å²	135	100.4 Å²	100.4	59%	0.587	52%	0.524	S	S	*	.	P	Polyproline II helix	trans	-52.1	118.1	170.1	-177.7	176.7	-178.3	173	0	109.9	D29	K27-D29 PolarHBondContact O-N 3.47Å; K27-D29 VanDerWaalsContact O-N 3.14Å
28	F	73.6	Confident	70.9	Confident	52 Å²	52	99.1 Å²	99.1	23%	0.228	51%	0.513	C	S	.	.	P	Polyproline II helix	trans	-56	116.5	177.8	-70.2	-86.8	0	0	0	111	N26 H35 E377 E378 I381	N26-F28 PolarHBondContact O-N 3.33Å; N26-F28 VanDerWaalsContact O-N 3.15Å; F28-H35 AromaticContact CD1-NE2 3.71Å; F28-E377 HydrophobicContact CD2-CB 4.23Å; F28-E377 HydrophobicContact CE2-CB 4.14Å; F28-E378 HydrophobicContact CE1-CG 4.33Å; F28-E378 HydrophobicContact CE2-CG 4.4Å; F28-E378 HydrophobicContact CZ-CB 4.38Å; F28-E378 HydrophobicContact CZ-CG 3.69Å; F28-I381 HydrophobicContact CB-CD1 4.21Å
29	D	81.7	Confident	72.6	Confident	31 Å²	31	95 Å²	95	17%	0.166	49%	0.486	C	S	.	.			trans	-128.5	119.2	175.4	-168.6	-21.7	0	0	0	109.1	K27 R31 D32 W219	K27-D29 PolarHBondContact O-N 3.47Å; K27-D29 VanDerWaalsContact O-N 3.14Å; D29-R31 PolarHBondContact O-N 2.89Å; D29-R31 VanDerWaalsContact OD1-CB 3.29Å; D29-R31 WeakPolarHBondContact OD1-CB 3.25Å; D29-R31 WeakPolarHBondContact OD1-CG 3.38Å; D29-R31 IonicContact OD1-CZ 3.43Å; D29-R31 PolarHBondContact OD1-N 2.85Å; D29-R31 IonicContact OD1-NE 3.56Å; D29-R31 PolarHBondContact OD1-NE 3.39Å; D29-R31 IonicContact OD1-NH2 3.43Å; D29-R31 IonicContact OD2-CZ 3.88Å; D29-R31 VanDerWaalsContact OD2-CZ 3.29Å; D29-R31 IonicContact OD2-NE 3.65Å; D29-R31 PolarHBondContact OD2-NE 2.92Å; D29-R31 IonicContact OD2-NH2 2.67Å; D29-R31 PolarHBondContact OD2-NH2 3.4Å; D29-D32 WeakPolarHBondContact O-CB 3.46Å; D29-D32 PolarHBondContact O-N 3.26Å; D29-W219 HydrophobicContact CB-CB 4.14Å
30	I	85.1	Confident	74.4	Confident	1 Å²	1	96.2 Å²	96.2	1%	0.005	48%	0.476	C	S	.	.	T	Hydrogen-bonded Turn	trans	-58.6	-14.4	176.8	-159.4	172.6	0	0	0	113.5	D32 K39 L103 I218 W219 L221 I381	I30-D32 VanDerWaalsContact C-N 3.32Å; I30-K39 HydrophobicContact CG1-CB 4.11Å; I30-L103 HydrophobicContact CD1-CD2 4.09Å; I30-I218 HydrophobicContact CG2-CG1 4.16Å; I30-I218 WeakPolarHBondContact CG2-O 3.31Å; I30-W219 PolarHBondContact N-O 3.02Å; I30-W219 VanDerWaalsContact N-O 3.17Å; I30-L221 HydrophobicContact CD1-CD1 3.61Å; I30-L221 HydrophobicContact CD1-CD2 4.33Å; I30-L221 HydrophobicContact CD1-CG 4.03Å; I30-I381 HydrophobicContact CB-CD1 4.27Å; I30-I381 HydrophobicContact CB-CG2 4.5Å; I30-I381 HydrophobicContact CD1-CG2 3.89Å; I30-I381 HydrophobicContact CG1-CG2 4.09Å
31	R	81.5	Confident	76.2	Confident	107 Å²	107	95.9 Å²	95.9	40%	0.404	48%	0.475	S	S	.	.	T	Hydrogen-bonded Turn	trans	-80.6	-13.1	175.4	-60.4	176.9	-65.7	174.3	5.4	113.3	D29 I218	D29-R31 PolarHBondContact O-N 2.89Å; D29-R31 VanDerWaalsContact OD1-CB 3.29Å; D29-R31 WeakPolarHBondContact OD1-CB 3.25Å; D29-R31 WeakPolarHBondContact OD1-CG 3.38Å; D29-R31 IonicContact OD1-CZ 3.43Å; D29-R31 PolarHBondContact OD1-N 2.85Å; D29-R31 IonicContact OD1-NE 3.56Å; D29-R31 PolarHBondContact OD1-NE 3.39Å; D29-R31 IonicContact OD1-NH2 3.43Å; D29-R31 IonicContact OD2-CZ 3.88Å; D29-R31 VanDerWaalsContact OD2-CZ 3.29Å; D29-R31 IonicContact OD2-NE 3.65Å; D29-R31 PolarHBondContact OD2-NE 2.92Å; D29-R31 IonicContact OD2-NH2 2.67Å; D29-R31 PolarHBondContact OD2-NH2 3.4Å; R31-I218 HydrophobicContact CG-CD1 4.48Å; R31-I218 HydrophobicContact CG-CG1 4.45Å
32	D	82.6	Confident	78.2	Confident	62 Å²	62	88.1 Å²	88.1	33%	0.332	43%	0.434	S	S	.	.	S	Bend	trans	-67.9	147.2	177.3	-166.2	1.1	0	0	0	111.1	D29 I30 H34 H35	D29-D32 WeakPolarHBondContact O-CB 3.46Å; D29-D32 PolarHBondContact O-N 3.26Å; I30-D32 VanDerWaalsContact C-N 3.32Å; D32-H34 PolarHBondContact O-N 2.9Å; D32-H34 IonicContact OD1-CD2 3.83Å; D32-H34 IonicContact OD2-CD2 3.49Å; D32-H34 PolarHBondContact OD2-CD2 3.02Å; D32-H35 PolarHBondContact O-N 3.33Å
33	E	80.9	Confident	80.1	Confident	169 Å²	169	81.7 Å²	81.7	79%	0.79	41%	0.407	S	S	*	.	G	3₁₀ helix	trans	-60.2	-31.5	-178.4	-66.6	-163.7	155.6	0	0	111.9	H35 K36	E33-H35 PolarHBondContact O-N 3.39Å; E33-K36 VanDerWaalsContact O-CB 3.25Å; E33-K36 WeakPolarHBondContact O-CB 3.5Å; E33-K36 PolarHBondContact O-N 2.98Å
34	H	84.5	Confident	82	Confident	138 Å²	138	78.6 Å²	78.6	64%	0.639	39%	0.39	S	S	*	.	G	3₁₀ helix	trans	-60.8	-27.3	176	-67.3	-58.8	0	0	0	113.5	D32	D32-H34 PolarHBondContact O-N 2.9Å; D32-H34 IonicContact OD1-CD2 3.83Å; D32-H34 IonicContact OD2-CD2 3.49Å; D32-H34 PolarHBondContact OD2-CD2 3.02Å
35	H	85.5	Confident	83.8	Confident	20 Å²	20	77.5 Å²	77.5	9%	0.093	38%	0.38	C	S	.	.	G	3₁₀ helix	trans	-105	15	-176.5	-58.3	85.1	0	0	0	112.8	Q20 F28 D32 E33 V37 A38 K39	Q20-H35 PolarHBondContact NE2-NE2 3.33Å; F28-H35 AromaticContact CD1-NE2 3.71Å; D32-H35 PolarHBondContact O-N 3.33Å; E33-H35 PolarHBondContact O-N 3.39Å; H35-V37 VanDerWaalsContact C-N 3.27Å; H35-V37 PolarHBondContact O-N 2.94Å; H35-A38 PolarHBondContact O-N 3.48Å; H35-A38 VanDerWaalsContact O-N 3.16Å; H35-K39 PolarHBondContact O-N 2.67Å
36	K	88.6	Confident	85.4	Confident	120 Å²	120	70.1 Å²	70.1	52%	0.522	33%	0.334	S	S	.	.	H	α-helix	trans	-54.7	-40	-177.4	-176.8	172.6	-178.3	178.9	0	112.9	E33 K39 Y40	E33-K36 VanDerWaalsContact O-CB 3.25Å; E33-K36 WeakPolarHBondContact O-CB 3.5Å; E33-K36 PolarHBondContact O-N 2.98Å; K36-K39 WeakPolarHBondContact O-CB 3.13Å; K36-K39 PolarHBondContact O-N 3.15Å; K36-Y40 HydrophobicContact CD-CE2 4.16Å; K36-Y40 HydrophobicContact CG-CD2 3.94Å; K36-Y40 HydrophobicContact CG-CE2 3.47Å; K36-Y40 VanDerWaalsContact CG-CE2 3.47Å; K36-Y40 WeakPolarHBondContact O-CD2 3.45Å; K36-Y40 PolarHBondContact O-N 2.85Å; K36-Y40 VanDerWaalsContact O-N 3.14Å
37	V	88.7	Confident	86.9	Confident	104 Å²	104	67.2 Å²	67.2	63%	0.63	32%	0.321	S	S	*	.	H	α-helix	trans	-65	-50.7	177.9	178.5	0	0	0	0	111.2	H35 K39 Y40 I41	H35-V37 VanDerWaalsContact C-N 3.27Å; H35-V37 PolarHBondContact O-N 2.94Å; V37-K39 VanDerWaalsContact C-N 3.26Å; V37-K39 PolarHBondContact O-N 3.37Å; V37-Y40 PolarHBondContact O-N 3.39Å; V37-I41 HydrophobicContact CG1-CD1 3.79Å; V37-I41 HydrophobicContact CG1-CG1 4.44Å; V37-I41 WeakPolarHBondContact O-CG1 3.38Å; V37-I41 PolarHBondContact O-N 3.46Å
38	A	89.2	Confident	88	Confident	11 Å²	11	65.3 Å²	65.3	9%	0.091	32%	0.316	C	S	.	.	H	α-helix	trans	-58.9	-39.3	178.3	0	0	0	0	0	111.9	H35 I41 A42 I381 I385	H35-A38 PolarHBondContact O-N 3.48Å; H35-A38 VanDerWaalsContact O-N 3.16Å; A38-I41 PolarHBondContact O-N 3.29Å; A38-A42 WeakPolarHBondContact O-CB 3.29Å; A38-A42 PolarHBondContact O-N 2.93Å; A38-I381 HydrophobicContact CB-CG2 4.47Å; A38-I385 HydrophobicContact CB-CD1 4.47Å
39	K	90.8	Very high	89	Confident	19 Å²	19	64.1 Å²	64.1	8%	0.083	31%	0.312	C	S	.	.	H	α-helix	trans	-58.6	-49.3	174.3	-175.8	-179.8	-179.7	168.7	0	112.6	I30 H35 K36 V37 A42 I43 L103 Q105	I30-K39 HydrophobicContact CG1-CB 4.11Å; H35-K39 PolarHBondContact O-N 2.67Å; K36-K39 WeakPolarHBondContact O-CB 3.13Å; K36-K39 PolarHBondContact O-N 3.15Å; V37-K39 VanDerWaalsContact C-N 3.26Å; V37-K39 PolarHBondContact O-N 3.37Å; K39-A42 PolarHBondContact O-N 3.35Å; K39-I43 HydrophobicContact CG-CD1 4.11Å; K39-I43 WeakPolarHBondContact O-CG1 3.39Å; K39-I43 PolarHBondContact O-N 2.92Å; K39-L103 WeakPolarHBondContact CE-O 3.42Å; K39-L103 HydrophobicContact CG-CD2 4.48Å; K39-L103 PolarHBondContact NZ-O 3.3Å; K39-Q105 PolarHBondContact NZ-O 3.05Å; K39-Q105 VanDerWaalsContact NZ-O 3.13Å
40	Y	90.3	Very high	89.7	Confident	139 Å²	139	63 Å²	63	55%	0.545	31%	0.306	S	S	.	.	H	α-helix	trans	-65.7	-39.5	178.1	-75.3	-62.5	0	0	0	112.5	K36 V37 A42 I43 L44	K36-Y40 HydrophobicContact CD-CE2 4.16Å; K36-Y40 HydrophobicContact CG-CD2 3.94Å; K36-Y40 HydrophobicContact CG-CE2 3.47Å; K36-Y40 VanDerWaalsContact CG-CE2 3.47Å; K36-Y40 WeakPolarHBondContact O-CD2 3.45Å; K36-Y40 PolarHBondContact O-N 2.85Å; K36-Y40 VanDerWaalsContact O-N 3.14Å; V37-Y40 PolarHBondContact O-N 3.39Å; Y40-A42 VanDerWaalsContact C-N 3.34Å; Y40-A42 PolarHBondContact O-N 2.91Å; Y40-I43 PolarHBondContact O-N 2.99Å; Y40-L44 WeakPolarHBondContact O-CB 3.23Å; Y40-L44 PolarHBondContact O-N 3.44Å
41	I	89.9	Confident	90.2	Very high	57 Å²	57	67.6 Å²	67.6	29%	0.292	33%	0.33	S	S	.	.	H	α-helix	trans	-60.4	-45.7	174.8	-68	171.7	0	0	0	110.2	F12 V37 A38 L44 L45	F12-I41 HydrophobicContact CE1-CD1 4.15Å; F12-I41 HydrophobicContact CE1-CG2 4.13Å; F12-I41 HydrophobicContact CZ-CG2 4.41Å; V37-I41 HydrophobicContact CG1-CD1 3.79Å; V37-I41 HydrophobicContact CG1-CG1 4.44Å; V37-I41 WeakPolarHBondContact O-CG1 3.38Å; V37-I41 PolarHBondContact O-N 3.46Å; A38-I41 PolarHBondContact O-N 3.29Å; I41-L44 PolarHBondContact O-N 3.43Å; I41-L45 WeakPolarHBondContact O-CB 3.44Å; I41-L45 PolarHBondContact O-N 3.46Å
42	A	92.5	Very high	90.9	Very high	0 Å²	0	66.8 Å²	66.8	0%	0	33%	0.328	C	S	.	.	H	α-helix	trans	-59.7	-47.9	177.4	0	0	0	0	0	112	A38 K39 Y40 L44 L45 F46 L221 I385	A38-A42 WeakPolarHBondContact O-CB 3.29Å; A38-A42 PolarHBondContact O-N 2.93Å; K39-A42 PolarHBondContact O-N 3.35Å; Y40-A42 VanDerWaalsContact C-N 3.34Å; Y40-A42 PolarHBondContact O-N 2.91Å; A42-L44 PolarHBondContact O-N 3.44Å; A42-L45 PolarHBondContact O-N 2.97Å; A42-F46 HydrophobicContact CB-CE2 4.49Å; A42-F46 VanDerWaalsContact O-CB 3.28Å; A42-F46 WeakPolarHBondContact O-CB 3.39Å; A42-F46 WeakPolarHBondContact O-CD1 3.42Å; A42-F46 WeakPolarHBondContact O-CG 3.34Å; A42-F46 PolarHBondContact O-N 3.09Å; A42-L221 HydrophobicContact CB-CD1 4.38Å; A42-I385 HydrophobicContact CB-CD1 3.84Å; A42-I385 HydrophobicContact CB-CG1 3.83Å; A42-I385 HydrophobicContact CB-CG2 4.33Å
43	I	92.4	Very high	91.5	Very high	23 Å²	23	63.9 Å²	63.9	12%	0.118	31%	0.312	C	S	.	.	H	α-helix	trans	-59.5	-48.7	178.6	-70.5	164.1	0	0	0	110.9	K39 Y40 T47 L100 L103 L104	K39-I43 HydrophobicContact CG-CD1 4.11Å; K39-I43 WeakPolarHBondContact O-CG1 3.39Å; K39-I43 PolarHBondContact O-N 2.92Å; Y40-I43 PolarHBondContact O-N 2.99Å; I43-T47 VanDerWaalsContact O-CB 3.29Å; I43-T47 WeakPolarHBondContact O-CB 3.46Å; I43-T47 PolarHBondContact O-N 3.17Å; I43-T47 PolarHBondContact O-OG1 3.2Å; I43-L100 HydrophobicContact CG2-CD1 4.1Å; I43-L103 HydrophobicContact CD1-CB 4.43Å; I43-L103 HydrophobicContact CG1-CB 4.01Å; I43-L103 HydrophobicContact CG1-CD1 4.43Å; I43-L104 HydrophobicContact CD1-CD2 3.91Å; I43-L104 HydrophobicContact CD1-CG 4.38Å; I43-L104 HydrophobicContact CG2-CD2 4.15Å
44	L	92.3	Very high	92.2	Very high	110 Å²	110	57.7 Å²	57.7	58%	0.576	28%	0.284	S	S	*	.	H	α-helix	trans	-62.2	-49.5	179.8	-179.9	63	0	0	0	111	Y40 I41 A42 T47 I48	Y40-L44 WeakPolarHBondContact O-CB 3.23Å; Y40-L44 PolarHBondContact O-N 3.44Å; I41-L44 PolarHBondContact O-N 3.43Å; A42-L44 PolarHBondContact O-N 3.44Å; L44-T47 PolarHBondContact O-N 3.39Å; L44-I48 HydrophobicContact CD1-CD1 3.85Å; L44-I48 HydrophobicContact CD1-CG1 4.36Å; L44-I48 HydrophobicContact CG-CD1 3.91Å; L44-I48 WeakPolarHBondContact O-CG1 3.2Å; L44-I48 PolarHBondContact O-N 3.23Å
45	L	93.2	Very high	92.7	Very high	65 Å²	65	55.5 Å²	55.5	34%	0.34	28%	0.276	S	S	.	.	H	α-helix	trans	-62.1	-47.9	-178.8	-177.5	61.6	0	0	0	111.6	I41 A42 T47 I48 L49 I385 S389	I41-L45 WeakPolarHBondContact O-CB 3.44Å; I41-L45 PolarHBondContact O-N 3.46Å; A42-L45 PolarHBondContact O-N 2.97Å; L45-T47 VanDerWaalsContact C-N 3.33Å; L45-T47 PolarHBondContact O-N 3.41Å; L45-I48 PolarHBondContact O-N 3.36Å; L45-L49 HydrophobicContact CD1-CD1 3.93Å; L45-L49 HydrophobicContact CD1-CG 4.15Å; L45-L49 HydrophobicContact CG-CD1 3.91Å; L45-L49 HydrophobicContact CG-CG 4.47Å; L45-L49 WeakPolarHBondContact O-CB 3.28Å; L45-L49 VanDerWaalsContact O-CG 3.27Å; L45-L49 WeakPolarHBondContact O-CG 3.47Å; L45-L49 PolarHBondContact O-N 3.33Å; L45-I385 HydrophobicContact CD2-CG2 4.01Å; L45-S389 WeakPolarHBondContact CD2-OG 3.4Å
46	F	95.1	Very high	93.1	Very high	1 Å²	1	54.9 Å²	54.9	0%	0.004	27%	0.274	C	S	.	.	H	α-helix	trans	-62.5	-41.6	178.1	-67.3	-5.9	0	0	0	111.3	A42 L49 L50 I99 L103 L221 I385 N388 S389 I392	A42-F46 HydrophobicContact CB-CE2 4.49Å; A42-F46 VanDerWaalsContact O-CB 3.28Å; A42-F46 WeakPolarHBondContact O-CB 3.39Å; A42-F46 WeakPolarHBondContact O-CD1 3.42Å; A42-F46 WeakPolarHBondContact O-CG 3.34Å; A42-F46 PolarHBondContact O-N 3.09Å; F46-L49 PolarHBondContact O-N 3.47Å; F46-L50 VanDerWaalsContact O-CB 3.22Å; F46-L50 WeakPolarHBondContact O-CB 3.43Å; F46-L50 WeakPolarHBondContact O-CD1 3.12Å; F46-L50 WeakPolarHBondContact O-CG 3.14Å; F46-L50 PolarHBondContact O-N 3.32Å; F46-I99 HydrophobicContact CD2-CG2 3.89Å; F46-I99 HydrophobicContact CE2-CG2 3.74Å; F46-L103 HydrophobicContact CD2-CD1 3.63Å; F46-L103 HydrophobicContact CE2-CD1 3.58Å; F46-L221 HydrophobicContact CE2-CD1 4.44Å; F46-L221 HydrophobicContact CZ-CD1 4.31Å; F46-I385 HydrophobicContact CE1-CG2 4.11Å; F46-I385 WeakPolarHBondContact CE1-O 3.39Å; F46-I385 HydrophobicContact CZ-CG2 4.45Å; F46-N388 HydrophobicContact CE1-CB 3.78Å; F46-N388 HydrophobicContact CE2-CB 4.17Å; F46-N388 HydrophobicContact CZ-CB 3.48Å; F46-N388 VanDerWaalsContact CZ-CB 3.48Å; F46-S389 WeakPolarHBondContact CE1-OG 3.43Å; F46-I392 HydrophobicContact CB-CD1 4.24Å; F46-I392 HydrophobicContact CD1-CD1 4.11Å; F46-I392 HydrophobicContact CG-CD1 4.21Å
47	T	94.7	Very high	93.4	Very high	48 Å²	48	49.2 Å²	49.2	29%	0.294	25%	0.249	S	C	.	.	H	α-helix	trans	-61.9	-47.6	178	-57.9	0	0	0	0	111.4	I43 L44 L45 L50 L51	I43-T47 VanDerWaalsContact O-CB 3.29Å; I43-T47 WeakPolarHBondContact O-CB 3.46Å; I43-T47 PolarHBondContact O-N 3.17Å; I43-T47 PolarHBondContact O-OG1 3.2Å; L44-T47 PolarHBondContact O-N 3.39Å; L45-T47 VanDerWaalsContact C-N 3.33Å; L45-T47 PolarHBondContact O-N 3.41Å; T47-L50 PolarHBondContact O-N 2.99Å; T47-L51 HydrophobicContact CG2-CD1 4.19Å; T47-L51 WeakPolarHBondContact O-CB 3.37Å; T47-L51 WeakPolarHBondContact O-CG 3.39Å; T47-L51 PolarHBondContact O-N 2.91Å
48	I	94.7	Very high	93.8	Very high	95 Å²	95	48.2 Å²	48.2	49%	0.487	24%	0.239	S	C	.	.	H	α-helix	trans	-62.5	-47.6	178.3	-68.6	169	0	0	0	110.8	L44 L45 L50 L51 Y52	L44-I48 HydrophobicContact CD1-CD1 3.85Å; L44-I48 HydrophobicContact CD1-CG1 4.36Å; L44-I48 HydrophobicContact CG-CD1 3.91Å; L44-I48 WeakPolarHBondContact O-CG1 3.2Å; L44-I48 PolarHBondContact O-N 3.23Å; L45-I48 PolarHBondContact O-N 3.36Å; I48-L50 VanDerWaalsContact C-N 3.34Å; I48-L50 PolarHBondContact O-N 3.46Å; I48-L51 PolarHBondContact O-N 3.08Å; I48-Y52 WeakPolarHBondContact O-CB 3.43Å; I48-Y52 PolarHBondContact O-N 3.31Å
49	L	95.1	Very high	93.9	Very high	26 Å²	26	50 Å²	50	14%	0.136	25%	0.248	C	C	.	.	H	α-helix	trans	-65.7	-36.5	-179.5	-70	176	0	0	0	112.2	L45 F46 S53 I392 L393	L45-L49 HydrophobicContact CD1-CD1 3.93Å; L45-L49 HydrophobicContact CD1-CG 4.15Å; L45-L49 HydrophobicContact CG-CD1 3.91Å; L45-L49 HydrophobicContact CG-CG 4.47Å; L45-L49 WeakPolarHBondContact O-CB 3.28Å; L45-L49 VanDerWaalsContact O-CG 3.27Å; L45-L49 WeakPolarHBondContact O-CG 3.47Å; L45-L49 PolarHBondContact O-N 3.33Å; F46-L49 PolarHBondContact O-N 3.47Å; L49-S53 WeakPolarHBondContact O-CB 3.37Å; L49-S53 PolarHBondContact O-N 3.25Å; L49-S53 PolarHBondContact O-OG 3.19Å; L49-I392 HydrophobicContact CB-CB 4.29Å; L49-I392 HydrophobicContact CB-CG2 3.65Å; L49-I392 WeakPolarHBondContact O-CG2 3.38Å; L49-L393 HydrophobicContact CD2-CD1 4.3Å
50	L	96.2	Very high	94	Very high	8 Å²	8	49.1 Å²	49.1	4%	0.042	24%	0.244	C	C	.	.	H	α-helix	trans	-64.7	-49.7	175	-78.6	168.4	0	0	0	111.2	F46 T47 I48 Y52 S53 I54 L92 Q95 M96 I392	F46-L50 VanDerWaalsContact O-CB 3.22Å; F46-L50 WeakPolarHBondContact O-CB 3.43Å; F46-L50 WeakPolarHBondContact O-CD1 3.12Å; F46-L50 WeakPolarHBondContact O-CG 3.14Å; F46-L50 PolarHBondContact O-N 3.32Å; T47-L50 PolarHBondContact O-N 2.99Å; I48-L50 VanDerWaalsContact C-N 3.34Å; I48-L50 PolarHBondContact O-N 3.46Å; L50-Y52 VanDerWaalsContact C-N 3.33Å; L50-Y52 PolarHBondContact O-N 3.27Å; L50-S53 PolarHBondContact O-N 3.33Å; L50-I54 WeakPolarHBondContact O-CB 3.28Å; L50-I54 VanDerWaalsContact O-CG1 3.26Å; L50-I54 WeakPolarHBondContact O-CG1 3.42Å; L50-I54 PolarHBondContact O-N 3.44Å; L50-L92 HydrophobicContact CD2-CB 4.13Å; L50-L92 HydrophobicContact CD2-CD2 3.92Å; L50-L92 HydrophobicContact CD2-CG 4.42Å; L50-Q95 HydrophobicContact CD1-CB 4.3Å; L50-Q95 HydrophobicContact CD2-CB 3.74Å; L50-M96 HydrophobicContact CD1-CG 4.09Å; L50-M96 HydrophobicContact CD2-CG 4.04Å; L50-I392 HydrophobicContact CD2-CD1 4.4Å; L50-I392 HydrophobicContact CD2-CG1 4.3Å; L50-I392 HydrophobicContact CD2-CG2 4.12Å; L50-I392 HydrophobicContact CG-CD1 4.18Å; L50-I392 HydrophobicContact CG-CG2 4.27Å
51	L	95.4	Very high	94.1	Very high	98 Å²	98	43.4 Å²	43.4	51%	0.513	23%	0.225	S	C	.	.	H	α-helix	trans	-58	-47.3	176.4	-74.1	172	0	0	0	111	T47 I48 S53 I54 I55	T47-L51 HydrophobicContact CG2-CD1 4.19Å; T47-L51 WeakPolarHBondContact O-CB 3.37Å; T47-L51 WeakPolarHBondContact O-CG 3.39Å; T47-L51 PolarHBondContact O-N 2.91Å; I48-L51 PolarHBondContact O-N 3.08Å; L51-S53 VanDerWaalsContact C-N 3.35Å; L51-S53 PolarHBondContact O-N 3.38Å; L51-I54 PolarHBondContact O-N 2.9Å; L51-I55 VanDerWaalsContact O-CB 3.32Å; L51-I55 WeakPolarHBondContact O-CB 3.04Å; L51-I55 WeakPolarHBondContact O-CD1 3.44Å; L51-I55 WeakPolarHBondContact O-CG1 3.46Å; L51-I55 PolarHBondContact O-N 3.32Å
52	Y	95.6	Very high	94.2	Very high	90 Å²	90	43.5 Å²	43.5	35%	0.353	23%	0.225	S	C	.	.	H	α-helix	trans	-56.9	-47.7	176.1	174.9	-113.1	0	0	0	112.1	I48 L50 I54 I55 S56 L393 A396 T400	I48-Y52 WeakPolarHBondContact O-CB 3.43Å; I48-Y52 PolarHBondContact O-N 3.31Å; L50-Y52 VanDerWaalsContact C-N 3.33Å; L50-Y52 PolarHBondContact O-N 3.27Å; Y52-I54 PolarHBondContact O-N 2.82Å; Y52-I55 PolarHBondContact O-N 3.4Å; Y52-S56 WeakPolarHBondContact O-CB 3.2Å; Y52-S56 PolarHBondContact O-N 3.45Å; Y52-S56 PolarHBondContact O-OG 3.44Å; Y52-S56 VanDerWaalsContact O-OG 3.13Å; Y52-L393 HydrophobicContact CD1-CD1 4.48Å; Y52-L393 HydrophobicContact CE1-CD1 4.16Å; Y52-A396 HydrophobicContact CD1-CB 3.62Å; Y52-A396 HydrophobicContact CE1-CB 3.41Å; Y52-A396 VanDerWaalsContact CE1-CB 3.41Å; Y52-T400 WeakPolarHBondContact OH-CG2 3.21Å; Y52-T400 PolarHBondContact OH-OG1 3.13Å
53	S	95.8	Very high	93.9	Very high	0 Å²	0	43.5 Å²	43.5	0%	0	23%	0.225	C	C	.	.	H	α-helix	trans	-64.2	-42.3	-179.4	-56.3	0	0	0	0	112.2	L49 L50 L51 N57 I392	L49-S53 WeakPolarHBondContact O-CB 3.37Å; L49-S53 PolarHBondContact O-N 3.25Å; L49-S53 PolarHBondContact O-OG 3.19Å; L50-S53 PolarHBondContact O-N 3.33Å; L51-S53 VanDerWaalsContact C-N 3.35Å; L51-S53 PolarHBondContact O-N 3.38Å; S53-N57 WeakPolarHBondContact O-CB 3.27Å; S53-N57 PolarHBondContact O-N 3.4Å; S53-N57 VanDerWaalsContact O-N 3.11Å; S53-N57 PolarHBondContact O-ND2 3.44Å; S53-I392 WeakPolarHBondContact OG-CG2 3.3Å; S53-I392 PolarHBondContact OG-O 3.26Å
54	I	96.5	Very high	93.7	Very high	39 Å²	39	42.5 Å²	42.5	20%	0.2	22%	0.22	C	C	.	.	H	α-helix	trans	-64.7	-50.5	177	-67.6	166	0	0	0	110.1	L50 L51 Y52 S56 N57 I58 L89 L92 M96	L50-I54 WeakPolarHBondContact O-CB 3.28Å; L50-I54 VanDerWaalsContact O-CG1 3.26Å; L50-I54 WeakPolarHBondContact O-CG1 3.42Å; L50-I54 PolarHBondContact O-N 3.44Å; L51-I54 PolarHBondContact O-N 2.9Å; Y52-I54 PolarHBondContact O-N 2.82Å; I54-S56 PolarHBondContact O-N 2.83Å; I54-N57 PolarHBondContact O-N 3.44Å; I54-I58 HydrophobicContact CG2-CD1 3.64Å; I54-I58 HydrophobicContact CG2-CG1 4.4Å; I54-I58 VanDerWaalsContact O-CG1 3.3Å; I54-I58 WeakPolarHBondContact O-CG1 3.05Å; I54-I58 PolarHBondContact O-N 3.36Å; I54-L89 HydrophobicContact CG1-CD2 4.46Å; I54-L92 HydrophobicContact CG1-CD1 3.73Å; I54-M96 HydrophobicContact CD1-CE 4.26Å; I54-M96 HydrophobicContact CD1-SD 3.78Å
55	I	95.1	Very high	93.4	Very high	93 Å²	93	43.4 Å²	43.4	48%	0.477	22%	0.22	S	C	.	.	H	α-helix	trans	-59.5	-48.5	-179.4	-69.6	165.9	0	0	0	110.5	L51 Y52 N57 I58 L59	L51-I55 VanDerWaalsContact O-CB 3.32Å; L51-I55 WeakPolarHBondContact O-CB 3.04Å; L51-I55 WeakPolarHBondContact O-CD1 3.44Å; L51-I55 WeakPolarHBondContact O-CG1 3.46Å; L51-I55 PolarHBondContact O-N 3.32Å; Y52-I55 PolarHBondContact O-N 3.4Å; I55-N57 PolarHBondContact O-N 2.97Å; I55-I58 PolarHBondContact O-N 3.4Å; I55-L59 HydrophobicContact CG2-CD1 3.83Å; I55-L59 HydrophobicContact CG2-CG 4.21Å; I55-L59 WeakPolarHBondContact O-CB 3.24Å; I55-L59 WeakPolarHBondContact O-CG 3.39Å; I55-L59 PolarHBondContact O-N 3.11Å
56	S	94.2	Very high	92.9	Very high	7 Å²	7	43.6 Å²	43.6	5%	0.049	23%	0.226	C	C	.	.	H	α-helix	trans	-61.7	-43.1	-180	-66	0	0	0	0	111.7	Y52 I54 I58 L59 M60 P399	Y52-S56 WeakPolarHBondContact O-CB 3.2Å; Y52-S56 PolarHBondContact O-N 3.45Å; Y52-S56 PolarHBondContact O-OG 3.44Å; Y52-S56 VanDerWaalsContact O-OG 3.13Å; I54-S56 PolarHBondContact O-N 2.83Å; S56-I58 PolarHBondContact O-N 3.01Å; S56-L59 PolarHBondContact O-N 3.02Å; S56-M60 PolarHBondContact O-N 3.25Å; S56-P399 WeakPolarHBondContact O-CB 3.29Å
57	N	95	Very high	91.7	Very high	0 Å²	0	44.2 Å²	44.2	0%	0	23%	0.232	C	C	.	.	H	α-helix	trans	-63.7	-39.9	176.1	-83.6	-78.6	0	0	0	112.4	S53 I54 I55 M60 A61 I85 N88 L89 C395 P399	S53-N57 WeakPolarHBondContact O-CB 3.27Å; S53-N57 PolarHBondContact O-N 3.4Å; S53-N57 VanDerWaalsContact O-N 3.11Å; S53-N57 PolarHBondContact O-ND2 3.44Å; I54-N57 PolarHBondContact O-N 3.44Å; I55-N57 PolarHBondContact O-N 2.97Å; N57-M60 PolarHBondContact O-N 2.92Å; N57-A61 PolarHBondContact O-N 3.41Å; N57-I85 HydrophobicContact CB-CG2 4.21Å; N57-N88 PolarHBondContact OD1-ND2 3.33Å; N57-L89 HydrophobicContact CB-CD2 4.24Å; N57-C395 PolarHBondContact ND2-O 3.01Å; N57-P399 HydrophobicContact CB-CG 4.22Å; N57-P399 VanDerWaalsContact CG-CG 3.46Å; N57-P399 VanDerWaalsContact OD1-CG 3.25Å; N57-P399 WeakPolarHBondContact OD1-CG 3.49Å
58	I	95.1	Very high	90.2	Very high	83 Å²	83	44.1 Å²	44.1	43%	0.426	24%	0.241	S	C	.	.	H	α-helix	trans	-64.6	-45.2	175	-69.8	170.1	0	0	0	110.7	I54 I55 S56 M60 A61 I62	I54-I58 HydrophobicContact CG2-CD1 3.64Å; I54-I58 HydrophobicContact CG2-CG1 4.4Å; I54-I58 VanDerWaalsContact O-CG1 3.3Å; I54-I58 WeakPolarHBondContact O-CG1 3.05Å; I54-I58 PolarHBondContact O-N 3.36Å; I55-I58 PolarHBondContact O-N 3.4Å; S56-I58 PolarHBondContact O-N 3.01Å; I58-M60 VanDerWaalsContact C-N 3.33Å; I58-M60 PolarHBondContact O-N 3.36Å; I58-A61 WeakPolarHBondContact O-CB 3.39Å; I58-A61 PolarHBondContact O-N 3.33Å; I58-A61 VanDerWaalsContact O-N 3.17Å; I58-I62 HydrophobicContact CG2-CD1 3.75Å; I58-I62 HydrophobicContact CG2-CG1 4.34Å; I58-I62 VanDerWaalsContact O-CG1 3.3Å; I58-I62 WeakPolarHBondContact O-CG1 3.5Å; I58-I62 PolarHBondContact O-N 3.34Å
59	L	92.4	Very high	88.6	Confident	50 Å²	50	49.6 Å²	49.6	26%	0.262	26%	0.262	S	S	.	.	H	α-helix	trans	-61.4	-41.1	177.4	-74.9	175.2	0	0	0	111.9	I55 S56 I62 A63 L403 I413	I55-L59 HydrophobicContact CG2-CD1 3.83Å; I55-L59 HydrophobicContact CG2-CG 4.21Å; I55-L59 WeakPolarHBondContact O-CB 3.24Å; I55-L59 WeakPolarHBondContact O-CG 3.39Å; I55-L59 PolarHBondContact O-N 3.11Å; S56-L59 PolarHBondContact O-N 3.02Å; L59-I62 PolarHBondContact O-N 2.84Å; L59-A63 WeakPolarHBondContact O-CB 3.33Å; L59-A63 PolarHBondContact O-N 3.45Å; L59-L403 HydrophobicContact CB-CD1 3.67Å; L59-L403 HydrophobicContact CD1-CD1 4.11Å; L59-I413 HydrophobicContact CB-CD1 4.08Å; L59-I413 HydrophobicContact CD2-CD1 4.3Å; L59-I413 HydrophobicContact CD2-CG1 4.44Å; L59-I413 HydrophobicContact CD2-CG2 4.39Å
60	M	92.1	Very high	87	Confident	0 Å²	0	55.7 Å²	55.7	0%	0	30%	0.295	C	S	.	.	H	α-helix	trans	-62.8	-44.4	173.1	-176.4	-178.7	-176.6	0	0	111.3	S56 N57 I58 I62 A63 L64 A81 I85 L398 P399 H402	S56-M60 PolarHBondContact O-N 3.25Å; N57-M60 PolarHBondContact O-N 2.92Å; I58-M60 VanDerWaalsContact C-N 3.33Å; I58-M60 PolarHBondContact O-N 3.36Å; M60-I62 VanDerWaalsContact C-N 3.34Å; M60-I62 PolarHBondContact O-N 3.33Å; M60-A63 PolarHBondContact O-N 3.18Å; M60-L64 HydrophobicContact CE-CD1 4.31Å; M60-L64 HydrophobicContact CG-CD1 4.22Å; M60-L64 VanDerWaalsContact O-CG 3.26Å; M60-L64 WeakPolarHBondContact O-CG 3.44Å; M60-L64 PolarHBondContact O-N 3.18Å; M60-A81 HydrophobicContact CE-CB 4.24Å; M60-I85 HydrophobicContact CB-CD1 4.29Å; M60-I85 HydrophobicContact CG-CD1 4Å; M60-I85 HydrophobicContact SD-CD1 4.15Å; M60-I85 HydrophobicContact SD-CG1 4.25Å; M60-L398 HydrophobicContact CE-CG 4.41Å; M60-L398 HydrophobicContact SD-CG 4.4Å; M60-P399 HydrophobicContact CB-CB 3.93Å; M60-P399 HydrophobicContact CB-CG 4.41Å; M60-P399 VanDerWaalsContact SD-CA 3.59Å; M60-P399 HydrophobicContact SD-CB 4.03Å; M60-P399 HydrophobicContact SD-CG 3.95Å; M60-H402 HydrophobicContact CE-CB 4.18Å; M60-H402 HydrophobicContact SD-CB 4.36Å
61	A	93.5	Very high	85.5	Confident	19 Å²	19	57.9 Å²	57.9	16%	0.157	31%	0.306	C	S	.	.	H	α-helix	trans	-59.2	-46.4	175.9	0	0	0	0	0	111.5	N57 I58 A63 L64 F65 I85	N57-A61 PolarHBondContact O-N 3.41Å; I58-A61 WeakPolarHBondContact O-CB 3.39Å; I58-A61 PolarHBondContact O-N 3.33Å; I58-A61 VanDerWaalsContact O-N 3.17Å; A61-A63 PolarHBondContact O-N 2.95Å; A61-L64 PolarHBondContact O-N 3.05Å; A61-F65 WeakPolarHBondContact O-CD2 3.37Å; A61-F65 PolarHBondContact O-N 3.3Å; A61-I85 HydrophobicContact CB-CD1 4.03Å
62	I	90.9	Very high	84.4	Confident	58 Å²	58	56.3 Å²	56.3	30%	0.297	30%	0.304	S	S	.	.	H	α-helix	trans	-58.2	-48.2	175.9	-70.8	169.5	0	0	0	110.5	I58 L59 M60 L64 F65 C66 L416	I58-I62 HydrophobicContact CG2-CD1 3.75Å; I58-I62 HydrophobicContact CG2-CG1 4.34Å; I58-I62 VanDerWaalsContact O-CG1 3.3Å; I58-I62 WeakPolarHBondContact O-CG1 3.5Å; I58-I62 PolarHBondContact O-N 3.34Å; L59-I62 PolarHBondContact O-N 2.84Å; M60-I62 VanDerWaalsContact C-N 3.34Å; M60-I62 PolarHBondContact O-N 3.33Å; I62-L64 VanDerWaalsContact C-N 3.27Å; I62-L64 PolarHBondContact O-N 3.03Å; I62-F65 PolarHBondContact O-N 2.96Å; I62-C66 HydrophobicContact CG2-CB 4.39Å; I62-C66 WeakPolarHBondContact O-CB 3.49Å; I62-C66 PolarHBondContact O-N 3.12Å; I62-L416 HydrophobicContact CG2-CD1 3.23Å
63	A	87.9	Confident	83.6	Confident	0 Å²	0	52.4 Å²	52.4	0%	0	29%	0.288	C	S	.	.	H	α-helix	trans	-59	-38.5	178.4	0	0	0	0	0	112.4	L59 M60 A61 L403 A409 I412	L59-A63 WeakPolarHBondContact O-CB 3.33Å; L59-A63 PolarHBondContact O-N 3.45Å; M60-A63 PolarHBondContact O-N 3.18Å; A61-A63 PolarHBondContact O-N 2.95Å; A63-L403 HydrophobicContact CB-CD2 4.48Å; A63-A409 HydrophobicContact CB-CB 3.8Å; A63-I412 WeakPolarHBondContact O-CD1 3.34Å
64	L	87.8	Confident	83.1	Confident	3 Å²	3	55.3 Å²	55.3	2%	0.016	31%	0.309	C	S	.	.	H	α-helix	trans	-71.6	-35.2	178.6	-66.1	172.7	0	0	0	113.3	M60 A61 I62 Y73 F77 V78 A81 I85	M60-L64 HydrophobicContact CE-CD1 4.31Å; M60-L64 HydrophobicContact CG-CD1 4.22Å; M60-L64 VanDerWaalsContact O-CG 3.26Å; M60-L64 WeakPolarHBondContact O-CG 3.44Å; M60-L64 PolarHBondContact O-N 3.18Å; A61-L64 PolarHBondContact O-N 3.05Å; I62-L64 VanDerWaalsContact C-N 3.27Å; I62-L64 PolarHBondContact O-N 3.03Å; L64-Y73 HydrophobicContact CD2-CD1 4.08Å; L64-Y73 HydrophobicContact CD2-CD2 4.35Å; L64-Y73 HydrophobicContact CD2-CE1 4.21Å; L64-Y73 HydrophobicContact CD2-CE2 4.48Å; L64-Y73 HydrophobicContact CD2-CG 4.18Å; L64-F77 HydrophobicContact CD2-CD1 4.18Å; L64-F77 HydrophobicContact CD2-CE1 3.67Å; L64-V78 HydrophobicContact CB-CG1 4.35Å; L64-A81 HydrophobicContact CD1-CB 3.74Å; L64-I85 HydrophobicContact CD1-CD1 4.03Å
65	F	86	Confident	82.7	Confident	128 Å²	128	61.3 Å²	61.3	56%	0.561	33%	0.329	S	S	*	.	H	α-helix	trans	-92.1	-31.7	-177	-75.2	-66.3	0	0	0	114.4	A61 I62 L82	A61-F65 WeakPolarHBondContact O-CD2 3.37Å; A61-F65 PolarHBondContact O-N 3.3Å; I62-F65 PolarHBondContact O-N 2.96Å; F65-L82 HydrophobicContact CE2-CD1 3.63Å; F65-L82 HydrophobicContact CE2-CD2 4.41Å; F65-L82 HydrophobicContact CZ-CD1 3.87Å; F65-L82 HydrophobicContact CZ-CD2 3.77Å; F65-L82 HydrophobicContact CZ-CG 4.38Å
66	C	82.3	Confident	82.5	Confident	69 Å²	69	57.2 Å²	57.2	47%	0.466	31%	0.309	S	S	.	.	H	α-helix	trans	-87	-2.4	-176.4	-66.5	0	0	0	0	113.8	I62 G68 I412 L416	I62-C66 HydrophobicContact CG2-CB 4.39Å; I62-C66 WeakPolarHBondContact O-CB 3.49Å; I62-C66 PolarHBondContact O-N 3.12Å; C66-G68 PolarHBondContact O-N 3.42Å; C66-I412 HydrophobicContact CB-CG2 3.96Å; C66-L416 HydrophobicContact CB-CD1 4.15Å
67	G	69.4	Low	82.3	Confident	14 Å²	14	57.1 Å²	57.1	14%	0.144	31%	0.307	C	S	.	.	S	Bend	trans	-64.3	2.5	-179.3	0	0	0	0	0	116.4	N71 I412	G67-N71 PolarHBondContact O-N 3.4Å; G67-I412 VanDerWaalsContact CA-CD1 3.49Å
68	G	64	Low	82.1	Confident	47 Å²	47	58 Å²	58	49%	0.485	31%	0.312	S	S	.	.			trans	69.1	-167.4	178.1	0	0	0	0	0	113.6	C66 D70 N71	C66-G68 PolarHBondContact O-N 3.42Å; G68-D70 VanDerWaalsContact C-N 3.26Å; G68-N71 VanDerWaalsContact O-CG 3.24Å; G68-N71 PolarHBondContact O-ND2 3.48Å; G68-N71 PolarHBondContact O-OD1 3.45Å
69	K	59.8	Low	82	Confident	209 Å²	209	55.4 Å²	55.4	91%	0.909	30%	0.299	S	S	*	.	T	Hydrogen-bonded Turn	trans	-72.5	-20	175.7	-82.6	-178	178	174.5	0	113.1	N71	K69-N71 VanDerWaalsContact C-N 3.26Å; K69-N71 PolarHBondContact O-N 2.79Å
70	D	62.9	Low	82.1	Confident	155 Å²	155	53 Å²	53	83%	0.829	29%	0.287	S	S	*	.	T	Hydrogen-bonded Turn	trans	-93.1	14.9	-177.9	-51.9	-36.5	0	0	0	111.8	G68 S72	G68-D70 VanDerWaalsContact C-N 3.26Å; D70-S72 PolarHBondContact O-N 2.89Å
71	N	64.5	Low	82.1	Confident	53 Å²	53	53 Å²	53	28%	0.283	29%	0.287	S	S	.	.			trans	-63.5	124.1	-179.6	59.2	-2.4	0	0	0	110.6	G67 G68 K69 Y73 E408	G67-N71 PolarHBondContact O-N 3.4Å; G68-N71 VanDerWaalsContact O-CG 3.24Å; G68-N71 PolarHBondContact O-ND2 3.48Å; G68-N71 PolarHBondContact O-OD1 3.45Å; K69-N71 VanDerWaalsContact C-N 3.26Å; K69-N71 PolarHBondContact O-N 2.79Å; N71-Y73 HydrophobicContact CB-CD2 4.31Å; N71-Y73 PolarHBondContact O-N 3.49Å; N71-Y73 VanDerWaalsContact O-N 3.07Å; N71-E408 WeakPolarHBondContact CA-OE1 3.43Å
72	S	71.4	Confident	82.1	Confident	66 Å²	66	54 Å²	54	46%	0.462	29%	0.29	S	S	.	.			trans	-67.8	-12.3	-179	74.7	0	0	0	0	112.5	D70 S74 E408	D70-S72 PolarHBondContact O-N 2.89Å; S72-S74 PolarHBondContact O-N 2.92Å; S72-E408 VanDerWaalsContact CB-OE2 3.27Å; S72-E408 WeakPolarHBondContact CB-OE2 3.45Å; S72-E408 PolarHBondContact N-OE1 3.27Å; S72-E408 PolarHBondContact OG-OE2 3.49Å
73	Y	79.6	Confident	82.4	Confident	8 Å²	8	52.4 Å²	52.4	3%	0.031	28%	0.281	C	S	.	.	S	Bend	trans	-71.3	119.9	-178.7	-60.4	-72.2	0	0	0	112.4	L64 N71 R75 F77 V78 Y342 H402 S406 E408	L64-Y73 HydrophobicContact CD2-CD1 4.08Å; L64-Y73 HydrophobicContact CD2-CD2 4.35Å; L64-Y73 HydrophobicContact CD2-CE1 4.21Å; L64-Y73 HydrophobicContact CD2-CE2 4.48Å; L64-Y73 HydrophobicContact CD2-CG 4.18Å; N71-Y73 HydrophobicContact CB-CD2 4.31Å; N71-Y73 PolarHBondContact O-N 3.49Å; N71-Y73 VanDerWaalsContact O-N 3.07Å; Y73-R75 PolarHBondContact O-N 3.31Å; Y73-F77 AromaticContact CD1-CD1 3.45Å; Y73-F77 HydrophobicContact CD1-CD1 3.45Å; Y73-F77 VanDerWaalsContact CD1-CD1 3.45Å; Y73-F77 AromaticContact CD1-CE1 3.38Å; Y73-F77 HydrophobicContact CD1-CE1 3.38Å; Y73-F77 HydrophobicContact CD1-CZ 4.49Å; Y73-F77 HydrophobicContact CE1-CD1 4.25Å; Y73-F77 AromaticContact CE1-CE1 3.72Å; Y73-F77 HydrophobicContact CE1-CE1 3.72Å; Y73-F77 HydrophobicContact CG-CD1 4.2Å; Y73-F77 HydrophobicContact CG-CE1 4.39Å; Y73-V78 HydrophobicContact CG-CG2 4.48Å; Y73-Y342 AromaticContact CD1-CE2 3.57Å; Y73-Y342 HydrophobicContact CD1-CE2 3.57Å; Y73-Y342 AromaticContact CD1-CZ 3.76Å; Y73-Y342 WeakPolarHBondContact CD1-OH 3.43Å; Y73-Y342 AromaticContact CE1-CE2 3.37Å; Y73-Y342 HydrophobicContact CE1-CE2 3.37Å; Y73-Y342 AromaticContact CE1-CZ 3.91Å; Y73-Y342 HydrophobicContact CG-CE2 4.5Å; Y73-H402 AromaticContact CE1-CE1 3.57Å; Y73-H402 AromaticContact CZ-CE1 3.68Å; Y73-H402 AromaticContact CZ-NE2 3.89Å; Y73-H402 PolarHBondContact OH-CE1 2.84Å; Y73-H402 PolarHBondContact OH-NE2 3.3Å; Y73-S406 PolarHBondContact OH-OG 3.35Å; Y73-E408 HydrophobicContact CE2-CG 4.38Å
74	S	84.4	Confident	82.7	Confident	61 Å²	61	52.4 Å²	52.4	43%	0.427	28%	0.281	S	S	.	.			trans	-57.5	140.1	168.2	76	0	0	0	0	111	S72 A76 F77 V78	S72-S74 PolarHBondContact O-N 2.92Å; S74-A76 PolarHBondContact O-N 3.49Å; S74-F77 WeakPolarHBondContact O-CB 3.34Å; S74-F77 PolarHBondContact O-N 3.45Å; S74-F77 WeakPolarHBondContact OG-CB 3.46Å; S74-F77 PolarHBondContact OG-N 3.21Å; S74-V78 PolarHBondContact O-N 2.97Å; S74-V78 VanDerWaalsContact O-N 3.1Å
75	R	88.5	Confident	83	Confident	165 Å²	165	52.6 Å²	52.6	62%	0.623	28%	0.282	S	S	*	.	H	α-helix	trans	-49.5	-37.5	174.9	-178.3	-179.4	178.7	177.3	5.3	112.7	Y73 V78 L79 Y191	Y73-R75 PolarHBondContact O-N 3.31Å; R75-V78 PolarHBondContact O-N 3.34Å; R75-L79 HydrophobicContact CG-CD1 3.98Å; R75-L79 HydrophobicContact CG-CG 4.45Å; R75-L79 VanDerWaalsContact O-CG 3.3Å; R75-L79 WeakPolarHBondContact O-CG 3.37Å; R75-L79 PolarHBondContact O-N 2.9Å; R75-Y191 PolarHBondContact NE-OH 3.42Å; R75-Y191 PolarHBondContact NH2-OH 2.88Å
76	A	91.6	Very high	83.5	Confident	7 Å²	7	49.5 Å²	49.5	6%	0.058	27%	0.27	C	S	.	.	H	α-helix	trans	-63.6	-46	178.6	0	0	0	0	0	112.2	S74 L79 I80 F185 L190	S74-A76 PolarHBondContact O-N 3.49Å; A76-L79 PolarHBondContact O-N 2.82Å; A76-I80 WeakPolarHBondContact O-CD1 2.91Å; A76-I80 VanDerWaalsContact O-CG1 3.26Å; A76-I80 WeakPolarHBondContact O-CG1 3.27Å; A76-I80 PolarHBondContact O-N 2.93Å; A76-F185 HydrophobicContact CB-CB 4.07Å; A76-L190 HydrophobicContact CB-CD2 3.71Å
77	F	89.6	Confident	84.2	Confident	4 Å²	4	46.2 Å²	46.2	2%	0.018	25%	0.248	C	C	.	.	H	α-helix	trans	-58.8	-49.3	175.8	176.1	-96.7	0	0	0	111.4	L64 Y73 S74 L79 I80 A81 L168	L64-F77 HydrophobicContact CD2-CD1 4.18Å; L64-F77 HydrophobicContact CD2-CE1 3.67Å; Y73-F77 AromaticContact CD1-CD1 3.45Å; Y73-F77 HydrophobicContact CD1-CD1 3.45Å; Y73-F77 VanDerWaalsContact CD1-CD1 3.45Å; Y73-F77 AromaticContact CD1-CE1 3.38Å; Y73-F77 HydrophobicContact CD1-CE1 3.38Å; Y73-F77 HydrophobicContact CD1-CZ 4.49Å; Y73-F77 HydrophobicContact CE1-CD1 4.25Å; Y73-F77 AromaticContact CE1-CE1 3.72Å; Y73-F77 HydrophobicContact CE1-CE1 3.72Å; Y73-F77 HydrophobicContact CG-CD1 4.2Å; Y73-F77 HydrophobicContact CG-CE1 4.39Å; S74-F77 WeakPolarHBondContact O-CB 3.34Å; S74-F77 PolarHBondContact O-N 3.45Å; S74-F77 WeakPolarHBondContact OG-CB 3.46Å; S74-F77 PolarHBondContact OG-N 3.21Å; F77-L79 PolarHBondContact O-N 3.42Å; F77-I80 PolarHBondContact O-N 3.22Å; F77-A81 HydrophobicContact CE1-CB 4.41Å; F77-A81 HydrophobicContact CZ-CB 4.44Å; F77-A81 WeakPolarHBondContact O-CB 3.26Å; F77-A81 PolarHBondContact O-N 2.88Å; F77-L168 HydrophobicContact CD2-CD1 3.56Å; F77-L168 HydrophobicContact CE2-CD1 3.84Å; F77-L168 HydrophobicContact CE2-CD2 4.43Å
78	V	90.2	Very high	85.4	Confident	18 Å²	18	45.7 Å²	45.7	11%	0.109	24%	0.242	C	C	.	.	H	α-helix	trans	-57.5	-47.9	180	176.5	0	0	0	0	111.2	L64 Y73 S74 R75 I80 A81 L82	L64-V78 HydrophobicContact CB-CG1 4.35Å; Y73-V78 HydrophobicContact CG-CG2 4.48Å; S74-V78 PolarHBondContact O-N 2.97Å; S74-V78 VanDerWaalsContact O-N 3.1Å; R75-V78 PolarHBondContact O-N 3.34Å; V78-I80 PolarHBondContact O-N 2.96Å; V78-A81 PolarHBondContact O-N 3.06Å; V78-L82 WeakPolarHBondContact O-CB 3.37Å; V78-L82 PolarHBondContact O-N 3.47Å
79	L	93.2	Very high	86.9	Confident	29 Å²	29	46.3 Å²	46.3	15%	0.152	23%	0.234	C	C	.	.	H	α-helix	trans	-64.8	-42.3	-178	-71	171.9	0	0	0	112.6	R75 A76 F77 Q83 L190 Y191 I194	R75-L79 HydrophobicContact CG-CD1 3.98Å; R75-L79 HydrophobicContact CG-CG 4.45Å; R75-L79 VanDerWaalsContact O-CG 3.3Å; R75-L79 WeakPolarHBondContact O-CG 3.37Å; R75-L79 PolarHBondContact O-N 2.9Å; A76-L79 PolarHBondContact O-N 2.82Å; F77-L79 PolarHBondContact O-N 3.42Å; L79-Q83 WeakPolarHBondContact O-CG 3.36Å; L79-Q83 PolarHBondContact O-N 3.39Å; L79-Q83 PolarHBondContact O-NE2 3.36Å; L79-Q83 VanDerWaalsContact O-NE2 3.1Å; L79-L190 HydrophobicContact CB-CD2 4.42Å; L79-L190 HydrophobicContact CD1-CD2 3.86Å; L79-Y191 HydrophobicContact CD1-CE1 3.92Å; L79-Y191 HydrophobicContact CD1-CE2 4.21Å; L79-Y191 HydrophobicContact CD2-CE1 4.17Å; L79-I194 HydrophobicContact CB-CD1 4Å
80	I	93.7	Very high	88.6	Confident	0 Å²	0	38.1 Å²	38.1	0%	0	20%	0.2	C	C	.	.	H	α-helix	trans	-70.4	-43.8	178.6	-62.8	164.1	0	0	0	110.5	A76 F77 V78 L82 Q83 L84 L167 L168 N171 L190	A76-I80 WeakPolarHBondContact O-CD1 2.91Å; A76-I80 VanDerWaalsContact O-CG1 3.26Å; A76-I80 WeakPolarHBondContact O-CG1 3.27Å; A76-I80 PolarHBondContact O-N 2.93Å; F77-I80 PolarHBondContact O-N 3.22Å; V78-I80 PolarHBondContact O-N 2.96Å; I80-L82 VanDerWaalsContact C-N 3.25Å; I80-L82 PolarHBondContact O-N 3.07Å; I80-Q83 WeakPolarHBondContact O-CB 3.22Å; I80-Q83 PolarHBondContact O-N 3.07Å; I80-L84 PolarHBondContact O-N 3.06Å; I80-L84 VanDerWaalsContact O-N 3.1Å; I80-L167 HydrophobicContact CD1-CD2 4.29Å; I80-L167 HydrophobicContact CD1-CG 3.99Å; I80-L167 HydrophobicContact CG1-CD2 4.05Å; I80-L167 HydrophobicContact CG1-CG 4.24Å; I80-L167 HydrophobicContact CG2-CG 4.49Å; I80-L168 HydrophobicContact CB-CD1 4.35Å; I80-L168 HydrophobicContact CG2-CB 3.79Å; I80-L168 HydrophobicContact CG2-CD1 4.06Å; I80-N171 HydrophobicContact CD1-CB 3.91Å; I80-L190 HydrophobicContact CD1-CD1 4.35Å; I80-L190 HydrophobicContact CG1-CD1 4.42Å
81	A	92.5	Very high	90.1	Very high	1 Å²	1	31 Å²	31	1%	0.008	16%	0.162	C	C	.	.	H	α-helix	trans	-60.7	-36.8	177.1	0	0	0	0	0	111.6	M60 L64 F77 V78 Q83 L84 I85	M60-A81 HydrophobicContact CE-CB 4.24Å; L64-A81 HydrophobicContact CD1-CB 3.74Å; F77-A81 HydrophobicContact CE1-CB 4.41Å; F77-A81 HydrophobicContact CZ-CB 4.44Å; F77-A81 WeakPolarHBondContact O-CB 3.26Å; F77-A81 PolarHBondContact O-N 2.88Å; V78-A81 PolarHBondContact O-N 3.06Å; A81-Q83 VanDerWaalsContact C-N 3.33Å; A81-Q83 PolarHBondContact O-N 3.24Å; A81-L84 WeakPolarHBondContact O-CB 3.42Å; A81-L84 PolarHBondContact O-N 2.84Å; A81-I85 WeakPolarHBondContact O-CG1 3.4Å; A81-I85 PolarHBondContact O-N 3.38Å
82	L	94.3	Very high	91.6	Very high	40 Å²	40	28.6 Å²	28.6	21%	0.209	15%	0.148	C	C	.	.	H	α-helix	trans	-61.6	-40	172.9	-172.8	66.2	0	0	0	112.3	F65 V78 I80 L84 I85 I86	F65-L82 HydrophobicContact CE2-CD1 3.63Å; F65-L82 HydrophobicContact CE2-CD2 4.41Å; F65-L82 HydrophobicContact CZ-CD1 3.87Å; F65-L82 HydrophobicContact CZ-CD2 3.77Å; F65-L82 HydrophobicContact CZ-CG 4.38Å; V78-L82 WeakPolarHBondContact O-CB 3.37Å; V78-L82 PolarHBondContact O-N 3.47Å; I80-L82 VanDerWaalsContact C-N 3.25Å; I80-L82 PolarHBondContact O-N 3.07Å; L82-L84 VanDerWaalsContact C-N 3.3Å; L82-L84 PolarHBondContact O-N 3.42Å; L82-I85 PolarHBondContact O-N 3.1Å; L82-I86 HydrophobicContact CG-CD1 4.18Å; L82-I86 VanDerWaalsContact O-CG1 3.29Å; L82-I86 WeakPolarHBondContact O-CG1 3.28Å; L82-I86 PolarHBondContact O-N 3.27Å
83	Q	96.8	Very high	92.6	Very high	23 Å²	23	28.1 Å²	28.1	11%	0.107	14%	0.14	C	C	.	.	H	α-helix	trans	-65.4	-35.9	176.1	-52.5	-41.4	-62.9	0	0	111.7	L79 I80 A81 I86 S87 F164 I194 W198	L79-Q83 WeakPolarHBondContact O-CG 3.36Å; L79-Q83 PolarHBondContact O-N 3.39Å; L79-Q83 PolarHBondContact O-NE2 3.36Å; L79-Q83 VanDerWaalsContact O-NE2 3.1Å; I80-Q83 WeakPolarHBondContact O-CB 3.22Å; I80-Q83 PolarHBondContact O-N 3.07Å; A81-Q83 VanDerWaalsContact C-N 3.33Å; A81-Q83 PolarHBondContact O-N 3.24Å; Q83-I86 PolarHBondContact O-N 3.4Å; Q83-S87 WeakPolarHBondContact O-CB 3.4Å; Q83-S87 PolarHBondContact O-N 3.27Å; Q83-S87 PolarHBondContact O-OG 2.79Å; Q83-F164 HydrophobicContact CB-CB 4.41Å; Q83-F164 HydrophobicContact CB-CD1 3.54Å; Q83-F164 HydrophobicContact CB-CD2 3.7Å; Q83-F164 HydrophobicContact CB-CE1 3.61Å; Q83-F164 HydrophobicContact CB-CE2 3.76Å; Q83-F164 HydrophobicContact CB-CG 3.6Å; Q83-F164 HydrophobicContact CB-CZ 3.72Å; Q83-F164 HydrophobicContact CG-CD1 3.89Å; Q83-F164 HydrophobicContact CG-CE1 3.56Å; Q83-F164 HydrophobicContact CG-CE2 4.37Å; Q83-F164 HydrophobicContact CG-CG 4.44Å; Q83-F164 HydrophobicContact CG-CZ 3.83Å; Q83-I194 HydrophobicContact CG-CG2 3.93Å; Q83-W198 HydrophobicContact CB-CZ2 4.39Å
84	L	94.6	Very high	93.2	Very high	1 Å²	1	27.7 Å²	27.7	1%	0.005	14%	0.139	C	C	.	.	H	α-helix	trans	-64.3	-44.2	173.1	-75.7	168.5	0	0	0	111.9	I80 A81 L82 I86 S87 N88 M161 F164 S165 L168 L398	I80-L84 PolarHBondContact O-N 3.06Å; I80-L84 VanDerWaalsContact O-N 3.1Å; A81-L84 WeakPolarHBondContact O-CB 3.42Å; A81-L84 PolarHBondContact O-N 2.84Å; L82-L84 VanDerWaalsContact C-N 3.3Å; L82-L84 PolarHBondContact O-N 3.42Å; L84-I86 PolarHBondContact O-N 3.4Å; L84-S87 PolarHBondContact O-N 2.98Å; L84-N88 WeakPolarHBondContact O-CB 3.43Å; L84-N88 VanDerWaalsContact O-CG 3.25Å; L84-N88 PolarHBondContact O-N 2.89Å; L84-M161 WeakPolarHBondContact CD2-O 3.13Å; L84-F164 HydrophobicContact CD2-CB 3.67Å; L84-F164 HydrophobicContact CG-CB 3.79Å; L84-S165 WeakPolarHBondContact CD2-OG 3.27Å; L84-L168 HydrophobicContact CD1-CB 4.49Å; L84-L168 HydrophobicContact CD1-CD2 3.86Å; L84-L398 HydrophobicContact CB-CD2 3.93Å; L84-L398 HydrophobicContact CD1-CD2 3.78Å; L84-L398 HydrophobicContact CG-CD2 4.34Å
85	I	94.6	Very high	93.5	Very high	6 Å²	6	24.9 Å²	24.9	3%	0.031	12%	0.119	C	C	.	.	H	α-helix	trans	-59.9	-46.8	175.6	-69.9	165.3	0	0	0	110.5	N57 M60 A61 L64 A81 L82 S87 N88 L89	N57-I85 HydrophobicContact CB-CG2 4.21Å; M60-I85 HydrophobicContact CB-CD1 4.29Å; M60-I85 HydrophobicContact CG-CD1 4Å; M60-I85 HydrophobicContact SD-CD1 4.15Å; M60-I85 HydrophobicContact SD-CG1 4.25Å; A61-I85 HydrophobicContact CB-CD1 4.03Å; L64-I85 HydrophobicContact CD1-CD1 4.03Å; A81-I85 WeakPolarHBondContact O-CG1 3.4Å; A81-I85 PolarHBondContact O-N 3.38Å; L82-I85 PolarHBondContact O-N 3.1Å; I85-S87 VanDerWaalsContact C-N 3.31Å; I85-S87 PolarHBondContact O-N 2.76Å; I85-N88 PolarHBondContact O-N 3.14Å; I85-L89 HydrophobicContact CG2-CD1 4.06Å; I85-L89 HydrophobicContact CG2-CG 4.49Å; I85-L89 WeakPolarHBondContact O-CG 3.17Å; I85-L89 PolarHBondContact O-N 2.7Å
86	I	95.9	Very high	93.6	Very high	63 Å²	63	20.2 Å²	20.2	32%	0.323	11%	0.105	S	C	.	.	H	α-helix	trans	-58.2	-47	175.6	-68.6	165.2	0	0	0	110.1	L82 Q83 L84 N88 L89 I90 W198	L82-I86 HydrophobicContact CG-CD1 4.18Å; L82-I86 VanDerWaalsContact O-CG1 3.29Å; L82-I86 WeakPolarHBondContact O-CG1 3.28Å; L82-I86 PolarHBondContact O-N 3.27Å; Q83-I86 PolarHBondContact O-N 3.4Å; L84-I86 PolarHBondContact O-N 3.4Å; I86-N88 PolarHBondContact O-N 3.47Å; I86-L89 PolarHBondContact O-N 2.51Å; I86-I90 HydrophobicContact CG2-CD1 3.74Å; I86-I90 HydrophobicContact CG2-CG1 4.35Å; I86-I90 VanDerWaalsContact O-CG1 3.28Å; I86-I90 WeakPolarHBondContact O-CG1 3.18Å; I86-I90 PolarHBondContact O-N 3.03Å; I86-W198 HydrophobicContact CG2-CH2 4.25Å; I86-W198 HydrophobicContact CG2-CZ2 4.26Å
87	S	96.3	Very high	93.4	Very high	0 Å²	0	22.5 Å²	22.5	0%	0	11%	0.114	C	C	.	.	H	α-helix	trans	-61.5	-43.6	179.6	-54.6	0	0	0	0	112	Q83 L84 I85 I90 Y91 S160	Q83-S87 WeakPolarHBondContact O-CB 3.4Å; Q83-S87 PolarHBondContact O-N 3.27Å; Q83-S87 PolarHBondContact O-OG 2.79Å; L84-S87 PolarHBondContact O-N 2.98Å; I85-S87 VanDerWaalsContact C-N 3.31Å; I85-S87 PolarHBondContact O-N 2.76Å; S87-I90 PolarHBondContact O-N 3.26Å; S87-Y91 VanDerWaalsContact O-CB 3.29Å; S87-Y91 WeakPolarHBondContact O-CB 3.44Å; S87-Y91 PolarHBondContact O-N 3.48Å; S87-S160 WeakPolarHBondContact OG-CB 3.29Å; S87-S160 PolarHBondContact OG-OG 3.37Å
88	N	95	Very high	93.3	Very high	4 Å²	4	22.4 Å²	22.4	2%	0.021	11%	0.113	C	C	.	.	H	α-helix	trans	-60.1	-46.5	175	-72	-16.6	0	0	0	111.2	N57 L84 I85 I86 Y91 L92 M161 C395	N57-N88 PolarHBondContact OD1-ND2 3.33Å; L84-N88 WeakPolarHBondContact O-CB 3.43Å; L84-N88 VanDerWaalsContact O-CG 3.25Å; L84-N88 PolarHBondContact O-N 2.89Å; I85-N88 PolarHBondContact O-N 3.14Å; I86-N88 PolarHBondContact O-N 3.47Å; N88-Y91 VanDerWaalsContact O-CB 3.28Å; N88-Y91 WeakPolarHBondContact O-CB 3.21Å; N88-Y91 PolarHBondContact O-N 3.32Å; N88-Y91 VanDerWaalsContact O-N 3.16Å; N88-L92 WeakPolarHBondContact O-CG 3.36Å; N88-L92 PolarHBondContact O-N 2.98Å; N88-L92 VanDerWaalsContact O-N 3.09Å; N88-M161 WeakPolarHBondContact OD1-CE 3.49Å; N88-M161 PolarHBondContact OD1-SD 2.95Å; N88-M161 VanDerWaalsContact OD1-SD 3.42Å; N88-C395 HydrophobicContact CB-CB 4.25Å; N88-C395 PolarHBondContact ND2-O 2.93Å
89	L	96.3	Very high	93.3	Very high	60 Å²	60	21.5 Å²	21.5	31%	0.314	11%	0.108	S	C	.	.	H	α-helix	trans	-64.7	-41.9	179.9	-68.9	174.1	0	0	0	111.9	I54 N57 I85 I86 Y91 L92 L93	I54-L89 HydrophobicContact CG1-CD2 4.46Å; N57-L89 HydrophobicContact CB-CD2 4.24Å; I85-L89 HydrophobicContact CG2-CD1 4.06Å; I85-L89 HydrophobicContact CG2-CG 4.49Å; I85-L89 WeakPolarHBondContact O-CG 3.17Å; I85-L89 PolarHBondContact O-N 2.7Å; I86-L89 PolarHBondContact O-N 2.51Å; L89-Y91 VanDerWaalsContact C-N 3.26Å; L89-Y91 PolarHBondContact O-N 2.85Å; L89-L92 PolarHBondContact O-N 3.17Å; L89-L93 PolarHBondContact O-N 3.38Å
90	I	95.2	Very high	93.1	Very high	37 Å²	37	21.5 Å²	21.5	19%	0.19	11%	0.108	C	C	.	.	H	α-helix	trans	-63.3	-37.2	174.4	-58.9	168.9	0	0	0	110.1	I86 S87 L92 L93 P94 L153 F156 S157	I86-I90 HydrophobicContact CG2-CD1 3.74Å; I86-I90 HydrophobicContact CG2-CG1 4.35Å; I86-I90 VanDerWaalsContact O-CG1 3.28Å; I86-I90 WeakPolarHBondContact O-CG1 3.18Å; I86-I90 PolarHBondContact O-N 3.03Å; S87-I90 PolarHBondContact O-N 3.26Å; I90-L92 VanDerWaalsContact C-N 3.25Å; I90-L92 PolarHBondContact O-N 2.97Å; I90-L93 HydrophobicContact CB-CD1 4.36Å; I90-L93 HydrophobicContact CG2-CD1 4.07Å; I90-L93 WeakPolarHBondContact O-CB 3.5Å; I90-L93 PolarHBondContact O-N 2.83Å; I90-L93 VanDerWaalsContact O-N 3.1Å; I90-P94 WeakPolarHBondContact O-CD 3.11Å; I90-L153 HydrophobicContact CG2-CB 4.44Å; I90-L153 HydrophobicContact CG2-CD2 4.21Å; I90-F156 HydrophobicContact CD1-CE1 4.05Å; I90-F156 HydrophobicContact CG2-CD1 4.33Å; I90-S157 WeakPolarHBondContact CB-OG 3.31Å; I90-S157 WeakPolarHBondContact CG2-OG 3.17Å
91	Y	94.5	Very high	92.7	Very high	6 Å²	6	23.4 Å²	23.4	2%	0.024	12%	0.12	C	C	.	.	H	α-helix	trans	-62.3	-31	176.8	-166.3	-86.3	0	0	0	113	S87 N88 L89 P94 F154 S157 M161 R360 V391 C395	S87-Y91 VanDerWaalsContact O-CB 3.29Å; S87-Y91 WeakPolarHBondContact O-CB 3.44Å; S87-Y91 PolarHBondContact O-N 3.48Å; N88-Y91 VanDerWaalsContact O-CB 3.28Å; N88-Y91 WeakPolarHBondContact O-CB 3.21Å; N88-Y91 PolarHBondContact O-N 3.32Å; N88-Y91 VanDerWaalsContact O-N 3.16Å; L89-Y91 VanDerWaalsContact C-N 3.26Å; L89-Y91 PolarHBondContact O-N 2.85Å; Y91-P94 WeakPolarHBondContact O-CD 3.28Å; Y91-F154 HydrophobicContact CD1-CE1 4.43Å; Y91-F154 HydrophobicContact CD2-CD1 4.22Å; Y91-F154 HydrophobicContact CE1-CD1 4.11Å; Y91-F154 AromaticContact CE1-CE1 3.97Å; Y91-F154 HydrophobicContact CE1-CE1 3.97Å; Y91-F154 AromaticContact CE2-CD1 3.68Å; Y91-F154 HydrophobicContact CE2-CD1 3.68Å; Y91-F154 HydrophobicContact CE2-CE1 4.37Å; Y91-F154 AromaticContact CZ-CD1 3.61Å; Y91-F154 AromaticContact CZ-CE1 3.9Å; Y91-S157 PolarHBondContact N-OG 3.22Å; Y91-M161 HydrophobicContact CD2-SD 3.99Å; Y91-M161 HydrophobicContact CG-SD 4.02Å; Y91-R360 PolarHBondContact OH-NH1 2.82Å; Y91-R360 VanDerWaalsContact OH-NH1 3.16Å; Y91-R360 PolarHBondContact OH-NH2 2.69Å; Y91-V391 HydrophobicContact CE1-CG1 3.31Å; Y91-V391 WeakPolarHBondContact OH-CG1 3.19Å; Y91-C395 WeakPolarHBondContact CD1-SG 3.37Å
92	L	95.2	Very high	92.4	Very high	1 Å²	1	24.2 Å²	24.2	1%	0.005	12%	0.124	C	C	.	.	H	α-helix	trans	-78.3	-19.4	175.9	-61.4	-179.7	0	0	0	113.2	L50 I54 N88 L89 I90 Q95 M96 I392 C395	L50-L92 HydrophobicContact CD2-CB 4.13Å; L50-L92 HydrophobicContact CD2-CD2 3.92Å; L50-L92 HydrophobicContact CD2-CG 4.42Å; I54-L92 HydrophobicContact CG1-CD1 3.73Å; N88-L92 WeakPolarHBondContact O-CG 3.36Å; N88-L92 PolarHBondContact O-N 2.98Å; N88-L92 VanDerWaalsContact O-N 3.09Å; L89-L92 PolarHBondContact O-N 3.17Å; I90-L92 VanDerWaalsContact C-N 3.25Å; I90-L92 PolarHBondContact O-N 2.97Å; L92-Q95 WeakPolarHBondContact O-CB 3.33Å; L92-Q95 PolarHBondContact O-N 2.88Å; L92-Q95 VanDerWaalsContact O-N 3.09Å; L92-M96 WeakPolarHBondContact O-CG 3.02Å; L92-M96 PolarHBondContact O-N 3.39Å; L92-I392 HydrophobicContact CD2-CG2 4.13Å; L92-C395 HydrophobicContact CD2-CB 3.9Å; L92-C395 HydrophobicContact CG-CB 4.36Å
93	L	92.7	Very high	92	Very high	56 Å²	56	22.3 Å²	22.3	29%	0.293	11%	0.114	S	C	.	.	H	α-helix	trans	-57.6	-48.1	-175.7	-61.7	173.1	0	0	0	112.7	L89 I90 Q95 M96 F97 L153	L89-L93 PolarHBondContact O-N 3.38Å; I90-L93 HydrophobicContact CB-CD1 4.36Å; I90-L93 HydrophobicContact CG2-CD1 4.07Å; I90-L93 WeakPolarHBondContact O-CB 3.5Å; I90-L93 PolarHBondContact O-N 2.83Å; I90-L93 VanDerWaalsContact O-N 3.1Å; L93-Q95 VanDerWaalsContact C-N 3.25Å; L93-Q95 PolarHBondContact O-N 3.21Å; L93-M96 PolarHBondContact O-N 3.41Å; L93-M96 VanDerWaalsContact O-N 3.12Å; L93-F97 HydrophobicContact CB-CD2 4.08Å; L93-F97 HydrophobicContact CB-CE2 4.41Å; L93-F97 HydrophobicContact CD2-CD2 4.22Å; L93-F97 HydrophobicContact CD2-CE2 3.68Å; L93-F97 WeakPolarHBondContact O-CB 3.43Å; L93-F97 WeakPolarHBondContact O-CD2 3.33Å; L93-F97 PolarHBondContact O-N 3.44Å; L93-L153 HydrophobicContact CB-CD1 4.47Å; L93-L153 HydrophobicContact CD1-CD1 4.35Å
94	P	91.3	Very high	91.4	Very high	0 Å²	0	23.6 Å²	23.6	0%	0	12%	0.121	C	C	.	.	H	α-helix	trans	-67.3	-27.5	179.5	-23.2	37.3	0	0	0	113	I90 Y91 M96 V98 I99 F150 L153 F154	I90-P94 WeakPolarHBondContact O-CD 3.11Å; Y91-P94 WeakPolarHBondContact O-CD 3.28Å; P94-M96 VanDerWaalsContact C-N 3.32Å; P94-V98 HydrophobicContact CB-CG2 4.35Å; P94-V98 WeakPolarHBondContact O-CA 3.49Å; P94-V98 WeakPolarHBondContact O-CB 3.29Å; P94-V98 PolarHBondContact O-N 3.22Å; P94-I99 PolarHBondContact O-N 3.44Å; P94-I99 VanDerWaalsContact O-N 3.09Å; P94-F150 WeakPolarHBondContact CG-O 3.05Å; P94-L153 HydrophobicContact CG-CB 3.88Å; P94-F154 HydrophobicContact CB-CD2 3.65Å; P94-F154 HydrophobicContact CB-CE1 4.31Å; P94-F154 HydrophobicContact CB-CE2 3.05Å; P94-F154 HydrophobicContact CB-CG 4.46Å; P94-F154 HydrophobicContact CB-CZ 3.47Å; P94-F154 VanDerWaalsContact CB-CZ 3.47Å; P94-F154 HydrophobicContact CG-CD2 3.78Å; P94-F154 HydrophobicContact CG-CE1 4.43Å; P94-F154 HydrophobicContact CG-CE2 3.66Å; P94-F154 HydrophobicContact CG-CG 4.22Å; P94-F154 HydrophobicContact CG-CZ 4.04Å
95	Q	92	Very high	90.6	Very high	1 Å²	1	28.3 Å²	28.3	1%	0.005	14%	0.143	C	C	.	.	I	π-helix	trans	-64.8	-41.4	173.1	-64.8	-72.9	-18.9	0	0	110.4	L50 L92 L93 I99 L100 F154 N388 I392	L50-Q95 HydrophobicContact CD1-CB 4.3Å; L50-Q95 HydrophobicContact CD2-CB 3.74Å; L92-Q95 WeakPolarHBondContact O-CB 3.33Å; L92-Q95 PolarHBondContact O-N 2.88Å; L92-Q95 VanDerWaalsContact O-N 3.09Å; L93-Q95 VanDerWaalsContact C-N 3.25Å; L93-Q95 PolarHBondContact O-N 3.21Å; Q95-I99 HydrophobicContact CG-CD1 4.39Å; Q95-I99 VanDerWaalsContact NE2-CD1 3.25Å; Q95-L100 WeakPolarHBondContact O-CB 3.31Å; Q95-L100 PolarHBondContact O-N 3.4Å; Q95-F154 HydrophobicContact CG-CE1 4.26Å; Q95-F154 HydrophobicContact CG-CZ 4.02Å; Q95-N388 PolarHBondContact NE2-OD1 2.91Å; Q95-I392 HydrophobicContact CB-CG1 4.43Å; Q95-I392 HydrophobicContact CG-CD1 4.37Å; Q95-I392 HydrophobicContact CG-CG1 3.89Å
96	M	90.7	Very high	89.2	Confident	67 Å²	67	30 Å²	30	33%	0.33	15%	0.154	S	C	.	.	I	π-helix	trans	-74.1	-36.9	178.6	-65.6	174.8	63.2	0	0	114.1	L50 I54 L92 L93 P94 P101	L50-M96 HydrophobicContact CD1-CG 4.09Å; L50-M96 HydrophobicContact CD2-CG 4.04Å; I54-M96 HydrophobicContact CD1-CE 4.26Å; I54-M96 HydrophobicContact CD1-SD 3.78Å; L92-M96 WeakPolarHBondContact O-CG 3.02Å; L92-M96 PolarHBondContact O-N 3.39Å; L93-M96 PolarHBondContact O-N 3.41Å; L93-M96 VanDerWaalsContact O-N 3.12Å; P94-M96 VanDerWaalsContact C-N 3.32Å; M96-P101 WeakPolarHBondContact O-CD 3.49Å; M96-P101 WeakPolarHBondContact O-CG 3.4Å
97	F	87.2	Confident	87.5	Confident	56 Å²	56	32.3 Å²	32.3	25%	0.246	17%	0.173	C	C	.	.	I	π-helix	trans	-106.8	-18	-169.5	-67.1	-64.9	0	0	0	114.5	L93 L125 F150	L93-F97 HydrophobicContact CB-CD2 4.08Å; L93-F97 HydrophobicContact CB-CE2 4.41Å; L93-F97 HydrophobicContact CD2-CD2 4.22Å; L93-F97 HydrophobicContact CD2-CE2 3.68Å; L93-F97 WeakPolarHBondContact O-CB 3.43Å; L93-F97 WeakPolarHBondContact O-CD2 3.33Å; L93-F97 PolarHBondContact O-N 3.44Å; F97-L125 HydrophobicContact CD1-CD1 4.19Å; F97-L125 HydrophobicContact CE1-CD1 4.22Å; F97-F150 HydrophobicContact CB-CD1 4.35Å; F97-F150 HydrophobicContact CB-CE1 4.21Å; F97-F150 HydrophobicContact CD2-CE1 4.29Å; F97-F150 HydrophobicContact CG-CE1 4.44Å
98	V	87.5	Confident	85.6	Confident	1 Å²	1	37.6 Å²	37.6	1%	0.006	21%	0.21	C	C	.	.	I	π-helix	trans	-110.4	-61.8	177.5	-175.1	0	0	0	0	109.2	P94 P101 E102 N147 F150 F216 W223	P94-V98 HydrophobicContact CB-CG2 4.35Å; P94-V98 WeakPolarHBondContact O-CA 3.49Å; P94-V98 WeakPolarHBondContact O-CB 3.29Å; P94-V98 PolarHBondContact O-N 3.22Å; V98-P101 WeakPolarHBondContact O-CD 3.22Å; V98-E102 WeakPolarHBondContact CG1-OE1 3.3Å; V98-E102 WeakPolarHBondContact O-CB 3.49Å; V98-E102 WeakPolarHBondContact O-CG 3.5Å; V98-E102 PolarHBondContact O-N 2.94Å; V98-N147 HydrophobicContact CG1-CB 4.48Å; V98-F150 HydrophobicContact CG2-CB 3.48Å; V98-F150 VanDerWaalsContact CG2-CB 3.48Å; V98-F150 HydrophobicContact CG2-CG 4.19Å; V98-F216 HydrophobicContact CG1-CB 4.16Å; V98-W223 HydrophobicContact CG1-CH2 4.13Å
99	I	89.4	Confident	83.5	Confident	0 Å²	0	40.1 Å²	40.1	0%	0	22%	0.224	C	C	.	.	I	π-helix	trans	-68.7	-52.9	-169.5	-64	176.5	0	0	0	112.2	F46 P94 Q95 E102 L103 F154 F216 W223 N388	F46-I99 HydrophobicContact CD2-CG2 3.89Å; F46-I99 HydrophobicContact CE2-CG2 3.74Å; P94-I99 PolarHBondContact O-N 3.44Å; P94-I99 VanDerWaalsContact O-N 3.09Å; Q95-I99 HydrophobicContact CG-CD1 4.39Å; Q95-I99 VanDerWaalsContact NE2-CD1 3.25Å; I99-E102 PolarHBondContact O-N 3.45Å; I99-L103 HydrophobicContact CG2-CD1 3.88Å; I99-L103 WeakPolarHBondContact O-CB 3.47Å; I99-L103 PolarHBondContact O-N 3.47Å; I99-F154 HydrophobicContact CD1-CZ 4.44Å; I99-F216 HydrophobicContact CB-CE1 4.19Å; I99-F216 HydrophobicContact CB-CZ 4.21Å; I99-F216 HydrophobicContact CD1-CD2 4.03Å; I99-F216 HydrophobicContact CD1-CE1 4.47Å; I99-F216 HydrophobicContact CD1-CE2 3.59Å; I99-F216 HydrophobicContact CD1-CZ 3.83Å; I99-F216 HydrophobicContact CG1-CD1 3.96Å; I99-F216 HydrophobicContact CG1-CD2 3.96Å; I99-F216 HydrophobicContact CG1-CE1 3.73Å; I99-F216 HydrophobicContact CG1-CE2 3.71Å; I99-F216 HydrophobicContact CG1-CG 4.07Å; I99-F216 HydrophobicContact CG1-CZ 3.58Å; I99-F216 HydrophobicContact CG2-CE1 3.98Å; I99-F216 HydrophobicContact CG2-CZ 3.79Å; I99-W223 HydrophobicContact CD1-CZ2 3.51Å; I99-W223 HydrophobicContact CG1-CZ2 3.8Å; I99-N388 WeakPolarHBondContact CD1-OD1 3.22Å
100	L	89.3	Confident	81.2	Confident	29 Å²	29	42 Å²	42	15%	0.152	24%	0.24	C	C	.	.	H	α-helix	trans	-64	-46.1	-176.8	-170.9	66.4	0	0	0	112	I43 Q95 L103 L104	I43-L100 HydrophobicContact CG2-CD1 4.1Å; Q95-L100 WeakPolarHBondContact O-CB 3.31Å; Q95-L100 PolarHBondContact O-N 3.4Å; L100-L103 PolarHBondContact O-N 3.41Å; L100-L104 HydrophobicContact CD1-CD1 4.45Å; L100-L104 HydrophobicContact CG-CD1 4.06Å; L100-L104 WeakPolarHBondContact O-CD1 3.14Å; L100-L104 VanDerWaalsContact O-CG 3.28Å; L100-L104 WeakPolarHBondContact O-CG 3.46Å; L100-L104 PolarHBondContact O-N 3.2Å
101	P	86	Confident	79.1	Confident	39 Å²	39	48.3 Å²	48.3	25%	0.253	26%	0.262	S	S	.	.	H	α-helix	trans	-66	-39.9	177.2	-24.4	38.2	0	0	0	113	M96 V98 L104 Q105	M96-P101 WeakPolarHBondContact O-CD 3.49Å; M96-P101 WeakPolarHBondContact O-CG 3.4Å; V98-P101 WeakPolarHBondContact O-CD 3.22Å; P101-L104 PolarHBondContact O-N 3.24Å; P101-Q105 WeakPolarHBondContact O-CG 3.41Å; P101-Q105 PolarHBondContact O-N 3.35Å
102	E	85.1	Confident	77	Confident	19 Å²	19	51.1 Å²	51.1	9%	0.089	28%	0.282	C	S	.	.	H	α-helix	trans	-62.4	-45.3	175	-77.6	-177.7	-150.4	0	0	111.3	V98 I99 L104 Q105 N147 F216 I218	V98-E102 WeakPolarHBondContact CG1-OE1 3.3Å; V98-E102 WeakPolarHBondContact O-CB 3.49Å; V98-E102 WeakPolarHBondContact O-CG 3.5Å; V98-E102 PolarHBondContact O-N 2.94Å; I99-E102 PolarHBondContact O-N 3.45Å; E102-L104 PolarHBondContact O-N 3.24Å; E102-Q105 WeakPolarHBondContact O-CB 3.33Å; E102-Q105 PolarHBondContact O-N 3.2Å; E102-Q105 VanDerWaalsContact O-N 3.09Å; E102-N147 PolarHBondContact OE1-ND2 3.26Å; E102-N147 PolarHBondContact OE1-OD1 3.39Å; E102-F216 WeakPolarHBondContact OE2-CD1 3.18Å; E102-I218 HydrophobicContact CB-CD1 3.74Å; E102-I218 WeakPolarHBondContact O-CD1 3.38Å
103	L	86.6	Confident	74.8	Confident	0 Å²	0	59 Å²	59	0%	0	32%	0.317	C	S	.	.	H	α-helix	trans	-57.8	-39.9	175.8	-90.2	169.8	0	0	0	111.7	I30 K39 I43 F46 I99 L100 Q105 L221	I30-L103 HydrophobicContact CD1-CD2 4.09Å; K39-L103 WeakPolarHBondContact CE-O 3.42Å; K39-L103 HydrophobicContact CG-CD2 4.48Å; K39-L103 PolarHBondContact NZ-O 3.3Å; I43-L103 HydrophobicContact CD1-CB 4.43Å; I43-L103 HydrophobicContact CG1-CB 4.01Å; I43-L103 HydrophobicContact CG1-CD1 4.43Å; F46-L103 HydrophobicContact CD2-CD1 3.63Å; F46-L103 HydrophobicContact CE2-CD1 3.58Å; I99-L103 HydrophobicContact CG2-CD1 3.88Å; I99-L103 WeakPolarHBondContact O-CB 3.47Å; I99-L103 PolarHBondContact O-N 3.47Å; L100-L103 PolarHBondContact O-N 3.41Å; L103-Q105 VanDerWaalsContact C-N 3.31Å; L103-Q105 PolarHBondContact O-N 3.39Å; L103-L221 HydrophobicContact CD1-CD2 4.11Å; L103-L221 HydrophobicContact CD2-CD2 3.59Å; L103-L221 HydrophobicContact CG-CD2 3.88Å
104	L	84.4	Confident	73	Confident	49 Å²	49	59.2 Å²	59.2	26%	0.257	32%	0.323	S	S	.	.	H	α-helix	trans	-72.4	-24.4	179.1	-72.2	162.2	0	0	0	113.1	I43 L100 P101 E102 T106 F115	I43-L104 HydrophobicContact CD1-CD2 3.91Å; I43-L104 HydrophobicContact CD1-CG 4.38Å; I43-L104 HydrophobicContact CG2-CD2 4.15Å; L100-L104 HydrophobicContact CD1-CD1 4.45Å; L100-L104 HydrophobicContact CG-CD1 4.06Å; L100-L104 WeakPolarHBondContact O-CD1 3.14Å; L100-L104 VanDerWaalsContact O-CG 3.28Å; L100-L104 WeakPolarHBondContact O-CG 3.46Å; L100-L104 PolarHBondContact O-N 3.2Å; P101-L104 PolarHBondContact O-N 3.24Å; E102-L104 PolarHBondContact O-N 3.24Å; L104-T106 PolarHBondContact O-N 2.89Å; L104-F115 HydrophobicContact CD1-CD1 4.38Å; L104-F115 HydrophobicContact CD1-CD2 3.91Å; L104-F115 HydrophobicContact CD1-CE1 3.84Å; L104-F115 HydrophobicContact CD1-CE2 3.31Å; L104-F115 HydrophobicContact CD1-CG 4.41Å; L104-F115 HydrophobicContact CD1-CZ 3.28Å; L104-F115 HydrophobicContact CD2-CE2 4.26Å; L104-F115 HydrophobicContact CG-CE2 4.35Å
105	Q	78.3	Confident	71.1	Confident	101 Å²	101	62.9 Å²	62.9	47%	0.472	34%	0.339	S	S	.	.			trans	-61.5	130.1	173.8	-73.2	171.8	27.4	0	0	109.9	K39 P101 E102 L103	K39-Q105 PolarHBondContact NZ-O 3.05Å; K39-Q105 VanDerWaalsContact NZ-O 3.13Å; P101-Q105 WeakPolarHBondContact O-CG 3.41Å; P101-Q105 PolarHBondContact O-N 3.35Å; E102-Q105 WeakPolarHBondContact O-CB 3.33Å; E102-Q105 PolarHBondContact O-N 3.2Å; E102-Q105 VanDerWaalsContact O-N 3.09Å; L103-Q105 VanDerWaalsContact C-N 3.31Å; L103-Q105 PolarHBondContact O-N 3.39Å
106	T	63.7	Low	69.1	Low	42 Å²	42	65.3 Å²	65.3	26%	0.258	36%	0.359	S	S	.	.			trans	-122	130.6	174.7	34.1	0	0	0	0	106	L104 S108 N109	L104-T106 PolarHBondContact O-N 2.89Å; T106-S108 PolarHBondContact O-N 3.26Å; T106-N109 HydrophobicContact CG2-CB 4.41Å; T106-N109 WeakPolarHBondContact OG1-CB 3.39Å
107	P	61.5	Low	67.4	Low	110 Å²	110	69.4 Å²	69.4	71%	0.714	38%	0.378	S	S	*	.	T	Hydrogen-bonded Turn	trans	-56.6	-23.7	-175.4	-25.1	32.5	0	0	0	114.1
108	S	56.5	Low	66	Low	112 Å²	112	70.4 Å²	70.4	78%	0.783	38%	0.384	S	S	*	.	T	Hydrogen-bonded Turn	trans	-129.7	1.4	-167.9	53.6	0	0	0	0	115.4	T106	T106-S108 PolarHBondContact O-N 3.26Å
109	N	49.3	Very low	64.7	Low	57 Å²	57	72 Å²	72	31%	0.305	40%	0.401	S	S	.	.			trans	-100.2	126.7	-167.8	-148.2	-22.3	0	0	0	113.4	T106 Y111 S112	T106-N109 HydrophobicContact CG2-CB 4.41Å; T106-N109 WeakPolarHBondContact OG1-CB 3.39Å; N109-Y111 WeakPolarHBondContact ND2-CD2 3.21Å; N109-Y111 PolarHBondContact O-N 2.97Å; N109-Y111 WeakPolarHBondContact OD1-CD2 3.12Å; N109-S112 WeakPolarHBondContact O-CB 3.46Å; N109-S112 PolarHBondContact O-N 3.41Å; N109-S112 PolarHBondContact O-OG 3.12Å
110	P	49.7	Very low	63.3	Low	100 Å²	100	78.8 Å²	78.8	65%	0.649	44%	0.437	S	S	*	.	T	Hydrogen-bonded Turn	trans	-55.7	-18.2	171.5	18.3	-32.3	0	0	0	114.6	S112 K113	P110-S112 PolarHBondContact O-N 3.02Å; P110-S112 VanDerWaalsContact O-N 3.17Å; P110-K113 WeakPolarHBondContact O-CB 3.37Å; P110-K113 PolarHBondContact O-N 3.15Å
111	Y	50.6	Low	62	Low	168 Å²	168	81.6 Å²	81.6	66%	0.659	45%	0.451	S	S	*	.	H	α-helix	trans	-63.9	-16	172.5	-65.3	-75.2	0	0	0	114.2	N109 K113 S114 F115	N109-Y111 WeakPolarHBondContact ND2-CD2 3.21Å; N109-Y111 PolarHBondContact O-N 2.97Å; N109-Y111 WeakPolarHBondContact OD1-CD2 3.12Å; Y111-K113 PolarHBondContact O-N 3.47Å; Y111-S114 PolarHBondContact O-N 2.84Å; Y111-F115 PolarHBondContact O-N 3.48Å
112	S	49	Very low	60.7	Low	65 Å²	65	81.5 Å²	81.5	46%	0.455	45%	0.448	S	S	.	.	H	α-helix	trans	-57.3	-31.5	168.3	59.5	0	0	0	0	112.2	N109 P110 A116	N109-S112 WeakPolarHBondContact O-CB 3.46Å; N109-S112 PolarHBondContact O-N 3.41Å; N109-S112 PolarHBondContact O-OG 3.12Å; P110-S112 PolarHBondContact O-N 3.02Å; P110-S112 VanDerWaalsContact O-N 3.17Å; S112-A116 PolarHBondContact O-N 3.14Å
113	K	50.5	Low	59.9	Low	167 Å²	167	85.3 Å²	85.3	73%	0.726	47%	0.468	S	S	*	.	H	α-helix	trans	-70	-42.1	169.3	-101.9	179.1	176.1	179.5	0	112.1	P110 Y111 F115 A116 E117	P110-K113 WeakPolarHBondContact O-CB 3.37Å; P110-K113 PolarHBondContact O-N 3.15Å; Y111-K113 PolarHBondContact O-N 3.47Å; K113-F115 VanDerWaalsContact C-N 3.32Å; K113-F115 PolarHBondContact O-N 3.21Å; K113-A116 CarbonylContact O-C 3.56Å; K113-A116 WeakPolarHBondContact O-CA 3.18Å; K113-A116 VanDerWaalsContact O-CB 3.28Å; K113-A116 WeakPolarHBondContact O-CB 3.48Å; K113-A116 PolarHBondContact O-N 3.18Å; K113-E117 PolarHBondContact O-N 3.33Å; K113-E117 VanDerWaalsContact O-N 3.13Å
114	S	53.7	Low	58.9	Low	60 Å²	60	89.6 Å²	89.6	42%	0.42	49%	0.491	S	S	.	.	H	α-helix	trans	-66.4	-32.3	-177.9	-167.1	0	0	0	0	112.5	Y111 E117 I118	Y111-S114 PolarHBondContact O-N 2.84Å; S114-E117 CarbonylContact O-C 3.42Å; S114-E117 WeakPolarHBondContact O-CA 3.3Å; S114-E117 WeakPolarHBondContact O-CB 3.32Å; S114-E117 PolarHBondContact O-N 3.47Å; S114-I118 PolarHBondContact O-N 3.47Å; S114-I118 VanDerWaalsContact O-N 3.12Å
115	F	51.3	Low	57.9	Low	78 Å²	78	90.4 Å²	90.4	34%	0.342	50%	0.495	S	S	.	.	H	α-helix	trans	-70.8	-31.7	171.7	-144.3	-86.5	0	0	0	112.6	L104 Y111 K113 E117 I118	L104-F115 HydrophobicContact CD1-CD1 4.38Å; L104-F115 HydrophobicContact CD1-CD2 3.91Å; L104-F115 HydrophobicContact CD1-CE1 3.84Å; L104-F115 HydrophobicContact CD1-CE2 3.31Å; L104-F115 HydrophobicContact CD1-CG 4.41Å; L104-F115 HydrophobicContact CD1-CZ 3.28Å; L104-F115 HydrophobicContact CD2-CE2 4.26Å; L104-F115 HydrophobicContact CG-CE2 4.35Å; Y111-F115 PolarHBondContact O-N 3.48Å; K113-F115 VanDerWaalsContact C-N 3.32Å; K113-F115 PolarHBondContact O-N 3.21Å; F115-E117 PolarHBondContact O-N 3.26Å; F115-I118 HydrophobicContact CD1-CD1 4.33Å; F115-I118 HydrophobicContact CD2-CD1 3.39Å; F115-I118 HydrophobicContact CD2-CG1 4.42Å; F115-I118 HydrophobicContact CE1-CD1 4.26Å; F115-I118 HydrophobicContact CE2-CD1 3.29Å; F115-I118 HydrophobicContact CG-CD1 3.92Å; F115-I118 HydrophobicContact CZ-CD1 3.76Å; F115-I118 PolarHBondContact O-N 3.2Å
116	A	51.8	Low	57.3	Low	52 Å²	52	91.5 Å²	91.5	43%	0.43	50%	0.498	S	S	.	.	H	α-helix	trans	-64.4	-18	166.8	0	0	0	0	0	112	S112 K113 N122	S112-A116 PolarHBondContact O-N 3.14Å; K113-A116 CarbonylContact O-C 3.56Å; K113-A116 WeakPolarHBondContact O-CA 3.18Å; K113-A116 VanDerWaalsContact O-CB 3.28Å; K113-A116 WeakPolarHBondContact O-CB 3.48Å; K113-A116 PolarHBondContact O-N 3.18Å; A116-N122 WeakPolarHBondContact O-CB 3.39Å; A116-N122 PolarHBondContact O-ND2 3.47Å
117	E	53.1	Low	57.6	Low	153 Å²	153	95.1 Å²	95.1	72%	0.715	51%	0.513	S	S	*	.	T	Hydrogen-bonded Turn	trans	-96.7	-4.3	174.8	-72.5	-172.3	170.9	0	0	114.9	K113 S114 F115 G119	K113-E117 PolarHBondContact O-N 3.33Å; K113-E117 VanDerWaalsContact O-N 3.13Å; S114-E117 CarbonylContact O-C 3.42Å; S114-E117 WeakPolarHBondContact O-CA 3.3Å; S114-E117 WeakPolarHBondContact O-CB 3.32Å; S114-E117 PolarHBondContact O-N 3.47Å; F115-E117 PolarHBondContact O-N 3.26Å; E117-G119 WeakPolarHBondContact O-CA 3.44Å; E117-G119 PolarHBondContact O-N 2.93Å
118	I	59	Low	57.9	Low	76 Å²	76	94.7 Å²	94.7	39%	0.39	50%	0.504	S	S	.	.			trans	-64.1	91.7	168.1	-63.3	178.8	0	0	0	107.1	S114 F115 L120 I121 N122	S114-I118 PolarHBondContact O-N 3.47Å; S114-I118 VanDerWaalsContact O-N 3.12Å; F115-I118 HydrophobicContact CD1-CD1 4.33Å; F115-I118 HydrophobicContact CD2-CD1 3.39Å; F115-I118 HydrophobicContact CD2-CG1 4.42Å; F115-I118 HydrophobicContact CE1-CD1 4.26Å; F115-I118 HydrophobicContact CE2-CD1 3.29Å; F115-I118 HydrophobicContact CG-CD1 3.92Å; F115-I118 HydrophobicContact CZ-CD1 3.76Å; F115-I118 PolarHBondContact O-N 3.2Å; I118-L120 VanDerWaalsContact C-N 3.25Å; I118-L120 PolarHBondContact O-N 3.29Å; I118-L120 VanDerWaalsContact O-N 3.11Å; I118-I121 PolarHBondContact O-N 3.35Å; I118-N122 PolarHBondContact O-N 2.92Å
119	G	59.1	Low	58.1	Low	34 Å²	34	94 Å²	94	35%	0.351	49%	0.491	S	S	.	.	H	α-helix	trans	-61.7	-34.6	-152.9	0	0	0	0	0	112.4	E117 I123	E117-G119 WeakPolarHBondContact O-CA 3.44Å; E117-G119 PolarHBondContact O-N 2.93Å; G119-I123 WeakPolarHBondContact O-CA 3.29Å; G119-I123 WeakPolarHBondContact O-CB 3.27Å; G119-I123 WeakPolarHBondContact O-CD1 3.23Å; G119-I123 WeakPolarHBondContact O-CG1 3.48Å; G119-I123 PolarHBondContact O-N 3.38Å
120	L	60.6	Low	58.8	Low	144 Å²	144	99.9 Å²	99.9	75%	0.754	51%	0.509	S	S	*	.	H	α-helix	trans	-68.3	-43.6	-175.9	-147.8	83	0	0	0	112.4	I118 L124	I118-L120 VanDerWaalsContact C-N 3.25Å; I118-L120 PolarHBondContact O-N 3.29Å; I118-L120 VanDerWaalsContact O-N 3.11Å; L120-L124 VanDerWaalsContact O-CB 3.31Å; L120-L124 WeakPolarHBondContact O-CB 3.36Å; L120-L124 PolarHBondContact O-N 3.48Å
121	I	63	Low	59.7	Low	88 Å²	88	106.2 Å²	106.2	45%	0.451	52%	0.52	S	S	.	.	H	α-helix	trans	-71.9	-44	-178.3	-62.7	174.5	0	0	0	109.7	I118 L124 L125	I118-I121 PolarHBondContact O-N 3.35Å; I121-L124 PolarHBondContact O-N 3.29Å; I121-L125 WeakPolarHBondContact O-CB 3.33Å; I121-L125 PolarHBondContact O-N 3.18Å
122	N	58.4	Low	60	Low	37 Å²	37	102.8 Å²	102.8	20%	0.198	52%	0.516	C	S	.	.	H	α-helix	trans	-72.2	-30.8	179	-156.9	11.5	0	0	0	112.2	A116 I118 K126	A116-N122 WeakPolarHBondContact O-CB 3.39Å; A116-N122 PolarHBondContact O-ND2 3.47Å; I118-N122 PolarHBondContact O-N 2.92Å; N122-K126 WeakPolarHBondContact O-CA 3.45Å; N122-K126 WeakPolarHBondContact O-CB 3.35Å; N122-K126 WeakPolarHBondContact O-CG 3.17Å; N122-K126 PolarHBondContact O-N 3.12Å
123	I	67.8	Low	60	Low	99 Å²	99	109 Å²	109	51%	0.508	53%	0.53	S	S	.	.	H	α-helix	trans	-66.2	-45.6	170.7	-71.4	164.5	0	0	0	109.8	G119 K126 M127	G119-I123 WeakPolarHBondContact O-CA 3.29Å; G119-I123 WeakPolarHBondContact O-CB 3.27Å; G119-I123 WeakPolarHBondContact O-CD1 3.23Å; G119-I123 WeakPolarHBondContact O-CG1 3.48Å; G119-I123 PolarHBondContact O-N 3.38Å; I123-K126 PolarHBondContact O-N 3.48Å; I123-M127 HydrophobicContact CG2-CG 4.39Å; I123-M127 HydrophobicContact CG2-SD 3.99Å; I123-M127 VanDerWaalsContact O-CB 3.25Å; I123-M127 WeakPolarHBondContact O-CB 3.36Å; I123-M127 WeakPolarHBondContact O-CG 3.45Å; I123-M127 PolarHBondContact O-N 3.5Å
124	L	65.5	Low	60	Low	90 Å²	90	104.5 Å²	104.5	47%	0.471	53%	0.532	S	S	.	.	H	α-helix	trans	-63.8	-45.3	178	-147.2	94.6	0	0	0	110.9	L120 I121 M127 I128	L120-L124 VanDerWaalsContact O-CB 3.31Å; L120-L124 WeakPolarHBondContact O-CB 3.36Å; L120-L124 PolarHBondContact O-N 3.48Å; I121-L124 PolarHBondContact O-N 3.29Å; L124-M127 WeakPolarHBondContact O-CB 3.26Å; L124-M127 PolarHBondContact O-N 3.48Å; L124-I128 HydrophobicContact CD2-CD1 4.17Å; L124-I128 HydrophobicContact CG-CD1 4.36Å; L124-I128 WeakPolarHBondContact O-CB 3.42Å; L124-I128 WeakPolarHBondContact O-CD1 3.27Å; L124-I128 WeakPolarHBondContact O-CG1 3.47Å; L124-I128 PolarHBondContact O-N 2.9Å
125	L	62.5	Low	59.5	Low	65 Å²	65	107.1 Å²	107.1	34%	0.34	54%	0.54	S	S	.	.	H	α-helix	trans	-64.8	-45.4	178.1	-159.5	85.8	0	0	0	110.7	F97 I121 M127 I128 L129	F97-L125 HydrophobicContact CD1-CD1 4.19Å; F97-L125 HydrophobicContact CE1-CD1 4.22Å; I121-L125 WeakPolarHBondContact O-CB 3.33Å; I121-L125 PolarHBondContact O-N 3.18Å; L125-M127 VanDerWaalsContact C-N 3.35Å; L125-M127 PolarHBondContact O-N 3.37Å; L125-I128 PolarHBondContact O-N 3.36Å; L125-L129 HydrophobicContact CD2-CD1 3.92Å; L125-L129 HydrophobicContact CG-CD1 3.81Å; L125-L129 WeakPolarHBondContact O-CB 3.34Å; L125-L129 WeakPolarHBondContact O-CD1 3.43Å; L125-L129 WeakPolarHBondContact O-CG 3.37Å; L125-L129 PolarHBondContact O-N 2.95Å
126	K	67.2	Low	59	Low	125 Å²	125	110.4 Å²	110.4	54%	0.543	56%	0.561	S	S	.	*	H	α-helix	trans	-63	-38.3	172.6	-80	176.1	179.6	173.5	0	111.4	N122 I123 R130	N122-K126 WeakPolarHBondContact O-CA 3.45Å; N122-K126 WeakPolarHBondContact O-CB 3.35Å; N122-K126 WeakPolarHBondContact O-CG 3.17Å; N122-K126 PolarHBondContact O-N 3.12Å; I123-K126 PolarHBondContact O-N 3.48Å; K126-R130 WeakPolarHBondContact O-CA 3.41Å; K126-R130 WeakPolarHBondContact O-CB 3.32Å; K126-R130 PolarHBondContact O-N 3.25Å
127	M	70.3	Confident	58.4	Low	117 Å²	117	116 Å²	116	58%	0.576	58%	0.582	S	S	*	*	H	α-helix	trans	-63.8	-45.3	176	-88.1	175.6	33.2	0	0	110.9	I123 L124 L125 R131	I123-M127 HydrophobicContact CG2-CG 4.39Å; I123-M127 HydrophobicContact CG2-SD 3.99Å; I123-M127 VanDerWaalsContact O-CB 3.25Å; I123-M127 WeakPolarHBondContact O-CB 3.36Å; I123-M127 WeakPolarHBondContact O-CG 3.45Å; I123-M127 PolarHBondContact O-N 3.5Å; L124-M127 WeakPolarHBondContact O-CB 3.26Å; L124-M127 PolarHBondContact O-N 3.48Å; L125-M127 VanDerWaalsContact C-N 3.35Å; L125-M127 PolarHBondContact O-N 3.37Å; M127-R131 WeakPolarHBondContact O-CB 3.19Å; M127-R131 PolarHBondContact O-N 3.33Å; M127-R131 VanDerWaalsContact O-N 3.09Å
128	I	66.1	Low	58	Low	101 Å²	101	112.9 Å²	112.9	52%	0.518	57%	0.57	S	S	.	*	H	α-helix	trans	-63.7	-48.5	177	-66.9	164.5	0	0	0	109.9	L124 L125 R131 T132	L124-I128 HydrophobicContact CD2-CD1 4.17Å; L124-I128 HydrophobicContact CG-CD1 4.36Å; L124-I128 WeakPolarHBondContact O-CB 3.42Å; L124-I128 WeakPolarHBondContact O-CD1 3.27Å; L124-I128 WeakPolarHBondContact O-CG1 3.47Å; L124-I128 PolarHBondContact O-N 2.9Å; L125-I128 PolarHBondContact O-N 3.36Å; I128-R131 PolarHBondContact O-N 3.06Å; I128-T132 PolarHBondContact O-N 2.84Å; I128-T132 PolarHBondContact O-OG1 3.39Å
129	L	61.2	Low	57.2	Low	97 Å²	97	120 Å²	120	51%	0.508	59%	0.591	S	S	.	*	H	α-helix	trans	-66.5	-39.4	178.9	-86	154.8	0	0	0	113.5	L125 R131 T132	L125-L129 HydrophobicContact CD2-CD1 3.92Å; L125-L129 HydrophobicContact CG-CD1 3.81Å; L125-L129 WeakPolarHBondContact O-CB 3.34Å; L125-L129 WeakPolarHBondContact O-CD1 3.43Å; L125-L129 WeakPolarHBondContact O-CG 3.37Å; L125-L129 PolarHBondContact O-N 2.95Å; L129-R131 PolarHBondContact O-N 3.48Å; L129-T132 WeakPolarHBondContact CA-OG1 3.46Å; L129-T132 CarbonylContact O-C 3.27Å; L129-T132 VanDerWaalsContact O-C 3.27Å; L129-T132 PolarHBondContact O-N 2.8Å; L129-T132 VanDerWaalsContact O-N 3.13Å; L129-T132 PolarHBondContact O-OG1 3.39Å
130	R	65	Low	56.4	Low	182 Å²	182	127.2 Å²	127.2	69%	0.687	62%	0.618	S	S	*	*	H	α-helix	trans	-72.4	-23.4	180	-162.1	-179.4	-141.3	-174.5	3	110.9	K126 R133	K126-R130 WeakPolarHBondContact O-CA 3.41Å; K126-R130 WeakPolarHBondContact O-CB 3.32Å; K126-R130 PolarHBondContact O-N 3.25Å; R130-R133 WeakPolarHBondContact O-CB 3.16Å; R130-R133 VanDerWaalsContact O-CG 3.25Å; R130-R133 WeakPolarHBondContact O-CG 3.24Å
131	R	67.6	Low	56.2	Low	233 Å²	233	125.8 Å²	125.8	88%	0.879	61%	0.611	S	S	*	*	H	α-helix	trans	-76.2	-27.3	169.6	-160.3	161.5	-172.9	159.7	1	112.1	M127 I128 L129 R133	M127-R131 WeakPolarHBondContact O-CB 3.19Å; M127-R131 PolarHBondContact O-N 3.33Å; M127-R131 VanDerWaalsContact O-N 3.09Å; I128-R131 PolarHBondContact O-N 3.06Å; L129-R131 PolarHBondContact O-N 3.48Å; R131-R133 VanDerWaalsContact C-N 3.3Å; R131-R133 PolarHBondContact O-N 3.3Å
132	T	57.2	Low	55.7	Low	95 Å²	95	125.1 Å²	125.1	58%	0.583	61%	0.607	S	S	*	*	T	Hydrogen-bonded Turn	trans	-94.2	44.6	170.2	35.3	0	0	0	0	112.9	I128 L129 G134	I128-T132 PolarHBondContact O-N 2.84Å; I128-T132 PolarHBondContact O-OG1 3.39Å; L129-T132 WeakPolarHBondContact CA-OG1 3.46Å; L129-T132 CarbonylContact O-C 3.27Å; L129-T132 VanDerWaalsContact O-C 3.27Å; L129-T132 PolarHBondContact O-N 2.8Å; L129-T132 VanDerWaalsContact O-N 3.13Å; L129-T132 PolarHBondContact O-OG1 3.39Å; T132-G134 PolarHBondContact O-N 3.5Å
133	R	50.1	Low	56	Low	195 Å²	195	126.8 Å²	126.8	74%	0.736	62%	0.618	S	S	*	*	T	Hydrogen-bonded Turn	trans	-50.9	-1.4	-171.5	-124.2	170.2	-169.2	174	2.7	118.2	R130 R131	R130-R133 WeakPolarHBondContact O-CB 3.16Å; R130-R133 VanDerWaalsContact O-CG 3.25Å; R130-R133 WeakPolarHBondContact O-CG 3.24Å; R131-R133 VanDerWaalsContact C-N 3.3Å; R131-R133 PolarHBondContact O-N 3.3Å
134	G	49.2	Very low	55.9	Low	74 Å²	74	125.1 Å²	125.1	76%	0.763	61%	0.613	S	S	*	*	T	Hydrogen-bonded Turn	trans	-97.9	0.4	-176.4	0	0	0	0	0	116.8	T132	T132-G134 PolarHBondContact O-N 3.5Å
135	L	44.1	Very low	55.4	Low	114 Å²	114	126 Å²	126	60%	0.597	61%	0.61	S	S	*	*			trans	-121.4	53.6	-171.6	-120.7	99.4	0	0	0	113.8	W145	L135-W145 HydrophobicContact CD2-CH2 3.33Å; L135-W145 HydrophobicContact CD2-CZ2 3.96Å; L135-W145 HydrophobicContact CD2-CZ3 3.9Å
136	L	40.3	Very low	55.7	Low	148 Å²	148	125.9 Å²	125.9	78%	0.775	61%	0.609	S	S	*	*			trans	-105.2	13.2	-169.6	-129.7	149.6	0	0	0	115.7
137	L	38.6	Very low	55.9	Low	169 Å²	169	121 Å²	121	89%	0.885	59%	0.589	S	S	*	*	S	Bend	trans	-112	19.9	-172.6	-109.4	163	0	0	0	116.8
138	I	44.5	Very low	56.2	Low	88 Å²	88	119.1 Å²	119.1	45%	0.451	58%	0.576	S	S	.	*			trans	-131	82.8	177.5	-50.8	177.1	0	0	0	109.7	N141 Q142	I138-N141 HydrophobicContact CG2-CB 3.55Å; I138-Q142 VanDerWaalsContact O-CB 3.29Å; I138-Q142 WeakPolarHBondContact O-CB 3.06Å; I138-Q142 WeakPolarHBondContact O-CG 3.18Å; I138-Q142 PolarHBondContact O-NE2 3.43Å
139	R	42.5	Very low	56.6	Low	224 Å²	224	119 Å²	119	85%	0.845	57%	0.572	S	S	*	*	S	Bend	trans	-89.1	-12.3	-171.7	-144.2	179.6	-157.9	177.2	5.9	115.4
140	M	43	Very low	57.5	Low	186 Å²	186	117.5 Å²	117.5	92%	0.916	56%	0.561	S	S	*	*	S	Bend	trans	-123.2	-12.1	178.7	-71.3	-155.5	178	0	0	115.7
141	N	55.6	Low	58.3	Low	114 Å²	114	108.8 Å²	108.8	61%	0.61	53%	0.528	S	S	*	.	S	Bend	trans	-96.3	9.6	168.7	-114	-1.3	0	0	0	113	I138 W145	I138-N141 HydrophobicContact CG2-CB 3.55Å; N141-W145 WeakPolarHBondContact O-CB 3.37Å; N141-W145 PolarHBondContact O-N 3.41Å; N141-W145 VanDerWaalsContact O-N 3.15Å
142	Q	53.6	Low	59.1	Low	75 Å²	75	99.6 Å²	99.6	35%	0.35	50%	0.499	S	S	.	.	H	α-helix	trans	-72.7	-41	-164.3	-136.3	170	15.5	0	0	112.9	I138 W145 I146	I138-Q142 VanDerWaalsContact O-CB 3.29Å; I138-Q142 WeakPolarHBondContact O-CB 3.06Å; I138-Q142 WeakPolarHBondContact O-CG 3.18Å; I138-Q142 PolarHBondContact O-NE2 3.43Å; Q142-W145 PolarHBondContact O-N 3.43Å; Q142-I146 HydrophobicContact CG-CD1 4.36Å; Q142-I146 WeakPolarHBondContact O-CB 3.3Å; Q142-I146 WeakPolarHBondContact O-CD1 3.33Å; Q142-I146 WeakPolarHBondContact O-CG1 3.23Å; Q142-I146 PolarHBondContact O-N 2.89Å
143	T	64.5	Low	60.6	Low	72 Å²	72	97.3 Å²	97.3	44%	0.442	48%	0.483	S	S	.	.	H	α-helix	trans	-62.6	-49.6	178.2	48.7	0	0	0	0	110.1	W145 I146 N147	T143-W145 VanDerWaalsContact C-N 3.31Å; T143-W145 PolarHBondContact O-N 3.46Å; T143-I146 PolarHBondContact O-N 3.42Å; T143-N147 WeakPolarHBondContact O-CB 3.43Å; T143-N147 PolarHBondContact O-N 3.49Å; T143-N147 PolarHBondContact O-ND2 2.99Å; T143-N147 PolarHBondContact O-OD1 3.01Å
144	T	65.3	Low	62.5	Low	64 Å²	64	88.3 Å²	88.3	39%	0.393	45%	0.45	S	S	.	.	H	α-helix	trans	-59.9	-41.4	178.8	-38.5	0	0	0	0	111.8	N147 Y148	T144-N147 WeakPolarHBondContact O-CB 3.34Å; T144-N147 PolarHBondContact O-N 3.27Å; T144-Y148 HydrophobicContact CG2-CD2 3.95Å; T144-Y148 HydrophobicContact CG2-CE2 3.6Å; T144-Y148 WeakPolarHBondContact O-CD2 3.07Å; T144-Y148 PolarHBondContact O-N 3.46Å
145	W	55.6	Low	64.5	Low	107 Å²	107	84.9 Å²	84.9	41%	0.405	41%	0.414	S	S	.	.	H	α-helix	trans	-71.5	-41.4	180	-167.4	87.5	0	0	0	113.5	L135 N141 Q142 T143 N147 Y148 K149	L135-W145 HydrophobicContact CD2-CH2 3.33Å; L135-W145 HydrophobicContact CD2-CZ2 3.96Å; L135-W145 HydrophobicContact CD2-CZ3 3.9Å; N141-W145 WeakPolarHBondContact O-CB 3.37Å; N141-W145 PolarHBondContact O-N 3.41Å; N141-W145 VanDerWaalsContact O-N 3.15Å; Q142-W145 PolarHBondContact O-N 3.43Å; T143-W145 VanDerWaalsContact C-N 3.31Å; T143-W145 PolarHBondContact O-N 3.46Å; W145-N147 VanDerWaalsContact C-N 3.27Å; W145-N147 PolarHBondContact O-N 3.39Å; W145-Y148 PolarHBondContact O-N 3.34Å; W145-K149 HydrophobicContact CD2-CD 4.24Å; W145-K149 HydrophobicContact CD2-CG 4.42Å; W145-K149 HydrophobicContact CE3-CD 4.08Å; W145-K149 HydrophobicContact CE3-CG 4.48Å; W145-K149 HydrophobicContact CH2-CD 3.47Å; W145-K149 VanDerWaalsContact CH2-CD 3.47Å; W145-K149 HydrophobicContact CZ2-CD 3.61Å; W145-K149 HydrophobicContact CZ2-CG 4.48Å; W145-K149 HydrophobicContact CZ3-CD 3.7Å; W145-K149 PolarHBondContact O-N 2.66Å
146	I	68.6	Low	66.9	Low	63 Å²	63	81.3 Å²	81.3	32%	0.323	39%	0.394	S	S	.	.	H	α-helix	trans	-58.3	-45.5	172.3	-71.7	167.6	0	0	0	109.1	Q142 T143 Y148 K149 F150	Q142-I146 HydrophobicContact CG-CD1 4.36Å; Q142-I146 WeakPolarHBondContact O-CB 3.3Å; Q142-I146 WeakPolarHBondContact O-CD1 3.33Å; Q142-I146 WeakPolarHBondContact O-CG1 3.23Å; Q142-I146 PolarHBondContact O-N 2.89Å; T143-I146 PolarHBondContact O-N 3.42Å; I146-Y148 PolarHBondContact O-N 2.92Å; I146-K149 PolarHBondContact O-N 2.93Å; I146-F150 HydrophobicContact CG2-CD2 3.67Å; I146-F150 HydrophobicContact CG2-CE2 4Å; I146-F150 WeakPolarHBondContact O-CB 3.21Å; I146-F150 WeakPolarHBondContact O-CD2 3.19Å; I146-F150 PolarHBondContact O-N 3.38Å
147	N	71	Confident	69.4	Low	24 Å²	24	74.2 Å²	74.2	13%	0.128	36%	0.357	C	S	.	.	H	α-helix	trans	-58.6	-52.7	178.6	-65.3	-2.6	0	0	0	110.6	V98 E102 T143 T144 W145 K149 F150 S151	V98-N147 HydrophobicContact CG1-CB 4.48Å; E102-N147 PolarHBondContact OE1-ND2 3.26Å; E102-N147 PolarHBondContact OE1-OD1 3.39Å; T143-N147 WeakPolarHBondContact O-CB 3.43Å; T143-N147 PolarHBondContact O-N 3.49Å; T143-N147 PolarHBondContact O-ND2 2.99Å; T143-N147 PolarHBondContact O-OD1 3.01Å; T144-N147 WeakPolarHBondContact O-CB 3.34Å; T144-N147 PolarHBondContact O-N 3.27Å; W145-N147 VanDerWaalsContact C-N 3.27Å; W145-N147 PolarHBondContact O-N 3.39Å; N147-K149 PolarHBondContact O-N 3.44Å; N147-F150 PolarHBondContact O-N 2.89Å; N147-S151 VanDerWaalsContact O-CB 3.27Å; N147-S151 WeakPolarHBondContact O-CB 3.39Å; N147-S151 PolarHBondContact O-N 3.34Å; N147-S151 PolarHBondContact O-OG 2.98Å
148	Y	75.9	Confident	72	Confident	77 Å²	77	67 Å²	67	30%	0.302	32%	0.318	S	S	.	.	H	α-helix	trans	-57.6	-45.3	179.2	-82.4	-63.1	0	0	0	112.9	T144 W145 I146 R214 R215	T144-Y148 HydrophobicContact CG2-CD2 3.95Å; T144-Y148 HydrophobicContact CG2-CE2 3.6Å; T144-Y148 WeakPolarHBondContact O-CD2 3.07Å; T144-Y148 PolarHBondContact O-N 3.46Å; W145-Y148 PolarHBondContact O-N 3.34Å; I146-Y148 PolarHBondContact O-N 2.92Å; Y148-R214 WeakPolarHBondContact CD1-O 3.38Å; Y148-R215 HydrophobicContact CE1-CB 4.04Å
149	K	75.7	Confident	74.4	Confident	98 Å²	98	63.1 Å²	63.1	43%	0.426	30%	0.298	S	S	.	.	H	α-helix	trans	-69.8	-48.1	-178.7	-80.4	-159.3	170.8	-176	0	112.9	W145 I146 N147 S151 S152	W145-K149 HydrophobicContact CD2-CD 4.24Å; W145-K149 HydrophobicContact CD2-CG 4.42Å; W145-K149 HydrophobicContact CE3-CD 4.08Å; W145-K149 HydrophobicContact CE3-CG 4.48Å; W145-K149 HydrophobicContact CH2-CD 3.47Å; W145-K149 VanDerWaalsContact CH2-CD 3.47Å; W145-K149 HydrophobicContact CZ2-CD 3.61Å; W145-K149 HydrophobicContact CZ2-CG 4.48Å; W145-K149 HydrophobicContact CZ3-CD 3.7Å; W145-K149 PolarHBondContact O-N 2.66Å; I146-K149 PolarHBondContact O-N 2.93Å; N147-K149 PolarHBondContact O-N 3.44Å; K149-S151 PolarHBondContact O-N 2.88Å; K149-S152 WeakPolarHBondContact O-CB 3.25Å; K149-S152 PolarHBondContact O-N 3.45Å; K149-S152 PolarHBondContact O-OG 3.5Å
150	F	79.7	Confident	76.9	Confident	65 Å²	65	52.5 Å²	52.5	29%	0.285	26%	0.258	S	S	.	.	H	α-helix	trans	-66.9	-26.9	179.3	-85.3	-94.8	0	0	0	112.2	P94 F97 V98 I146 N147 S152 L153	P94-F150 WeakPolarHBondContact CG-O 3.05Å; F97-F150 HydrophobicContact CB-CD1 4.35Å; F97-F150 HydrophobicContact CB-CE1 4.21Å; F97-F150 HydrophobicContact CD2-CE1 4.29Å; F97-F150 HydrophobicContact CG-CE1 4.44Å; V98-F150 HydrophobicContact CG2-CB 3.48Å; V98-F150 VanDerWaalsContact CG2-CB 3.48Å; V98-F150 HydrophobicContact CG2-CG 4.19Å; I146-F150 HydrophobicContact CG2-CD2 3.67Å; I146-F150 HydrophobicContact CG2-CE2 4Å; I146-F150 WeakPolarHBondContact O-CB 3.21Å; I146-F150 WeakPolarHBondContact O-CD2 3.19Å; I146-F150 PolarHBondContact O-N 3.38Å; N147-F150 PolarHBondContact O-N 2.89Å; F150-S152 PolarHBondContact O-N 3.32Å; F150-L153 HydrophobicContact CD1-CD1 3.73Å; F150-L153 HydrophobicContact CE1-CD1 4.19Å; F150-L153 HydrophobicContact CG-CD1 4.49Å; F150-L153 VanDerWaalsContact O-CB 3.32Å; F150-L153 WeakPolarHBondContact O-CB 3.33Å; F150-L153 PolarHBondContact O-N 3.34Å; F150-L153 VanDerWaalsContact O-N 3.1Å
151	S	81.2	Confident	79.4	Confident	0 Å²	0	44.3 Å²	44.3	0%	0	22%	0.217	C	C	.	.	H	α-helix	trans	-61.1	-28.1	174.6	-59.1	0	0	0	0	113.4	N147 K149 L153 F154 R214 W223	N147-S151 VanDerWaalsContact O-CB 3.27Å; N147-S151 WeakPolarHBondContact O-CB 3.39Å; N147-S151 PolarHBondContact O-N 3.34Å; N147-S151 PolarHBondContact O-OG 2.98Å; K149-S151 PolarHBondContact O-N 2.88Å; S151-L153 VanDerWaalsContact C-N 3.26Å; S151-L153 PolarHBondContact O-N 3.1Å; S151-F154 PolarHBondContact O-N 3.04Å; S151-R214 WeakPolarHBondContact CB-O 3.32Å; S151-R214 PolarHBondContact OG-O 3.01Å; S151-W223 WeakPolarHBondContact OG-CZ3 3.48Å
152	S	84.8	Confident	81.1	Confident	39 Å²	39	38.9 Å²	38.9	27%	0.273	19%	0.188	S	C	.	.	H	α-helix	trans	-67.7	-28.9	178	71.1	0	0	0	0	112.2	K149 F150 F154 S155 F156	K149-S152 WeakPolarHBondContact O-CB 3.25Å; K149-S152 PolarHBondContact O-N 3.45Å; K149-S152 PolarHBondContact O-OG 3.5Å; F150-S152 PolarHBondContact O-N 3.32Å; S152-F154 PolarHBondContact O-N 2.92Å; S152-S155 WeakPolarHBondContact O-CB 3.36Å; S152-S155 PolarHBondContact O-N 3.35Å; S152-F156 PolarHBondContact O-N 3.43Å; S152-F156 VanDerWaalsContact O-N 3.13Å
153	L	89.9	Confident	83.2	Confident	47 Å²	47	36.8 Å²	36.8	25%	0.246	18%	0.177	C	C	.	.	H	α-helix	trans	-61.9	-28.8	176.4	-63.8	176.6	0	0	0	112.2	I90 L93 P94 F150 S151 S155 S157	I90-L153 HydrophobicContact CG2-CB 4.44Å; I90-L153 HydrophobicContact CG2-CD2 4.21Å; L93-L153 HydrophobicContact CB-CD1 4.47Å; L93-L153 HydrophobicContact CD1-CD1 4.35Å; P94-L153 HydrophobicContact CG-CB 3.88Å; F150-L153 HydrophobicContact CD1-CD1 3.73Å; F150-L153 HydrophobicContact CE1-CD1 4.19Å; F150-L153 HydrophobicContact CG-CD1 4.49Å; F150-L153 VanDerWaalsContact O-CB 3.32Å; F150-L153 WeakPolarHBondContact O-CB 3.33Å; F150-L153 PolarHBondContact O-N 3.34Å; F150-L153 VanDerWaalsContact O-N 3.1Å; S151-L153 VanDerWaalsContact C-N 3.26Å; S151-L153 PolarHBondContact O-N 3.1Å; L153-S155 VanDerWaalsContact C-N 3.34Å; L153-S157 WeakPolarHBondContact O-CB 3.2Å; L153-S157 PolarHBondContact O-N 2.9Å; L153-S157 PolarHBondContact O-OG 3.4Å
154	F	89.7	Confident	84.7	Confident	7 Å²	7	33.3 Å²	33.3	3%	0.031	16%	0.156	C	C	.	.	H	α-helix	trans	-62.7	-42	172.6	-84.4	-65.7	0	0	0	112.5	Y91 P94 Q95 I99 S151 S152 Y158 W223	Y91-F154 HydrophobicContact CD1-CE1 4.43Å; Y91-F154 HydrophobicContact CD2-CD1 4.22Å; Y91-F154 HydrophobicContact CE1-CD1 4.11Å; Y91-F154 AromaticContact CE1-CE1 3.97Å; Y91-F154 HydrophobicContact CE1-CE1 3.97Å; Y91-F154 AromaticContact CE2-CD1 3.68Å; Y91-F154 HydrophobicContact CE2-CD1 3.68Å; Y91-F154 HydrophobicContact CE2-CE1 4.37Å; Y91-F154 AromaticContact CZ-CD1 3.61Å; Y91-F154 AromaticContact CZ-CE1 3.9Å; P94-F154 HydrophobicContact CB-CD2 3.65Å; P94-F154 HydrophobicContact CB-CE1 4.31Å; P94-F154 HydrophobicContact CB-CE2 3.05Å; P94-F154 HydrophobicContact CB-CG 4.46Å; P94-F154 HydrophobicContact CB-CZ 3.47Å; P94-F154 VanDerWaalsContact CB-CZ 3.47Å; P94-F154 HydrophobicContact CG-CD2 3.78Å; P94-F154 HydrophobicContact CG-CE1 4.43Å; P94-F154 HydrophobicContact CG-CE2 3.66Å; P94-F154 HydrophobicContact CG-CG 4.22Å; P94-F154 HydrophobicContact CG-CZ 4.04Å; Q95-F154 HydrophobicContact CG-CE1 4.26Å; Q95-F154 HydrophobicContact CG-CZ 4.02Å; I99-F154 HydrophobicContact CD1-CZ 4.44Å; S151-F154 PolarHBondContact O-N 3.04Å; S152-F154 PolarHBondContact O-N 2.92Å; F154-Y158 WeakPolarHBondContact O-CB 3.48Å; F154-Y158 PolarHBondContact O-N 3.33Å; F154-W223 HydrophobicContact CD2-CD2 4.29Å; F154-W223 AromaticContact CD2-CE2 3.92Å; F154-W223 HydrophobicContact CD2-CE3 4.45Å; F154-W223 AromaticContact CD2-CH2 3.9Å; F154-W223 HydrophobicContact CD2-CH2 3.9Å; F154-W223 AromaticContact CD2-CZ2 3.78Å; F154-W223 HydrophobicContact CD2-CZ2 3.78Å; F154-W223 HydrophobicContact CD2-CZ3 4.27Å; F154-W223 HydrophobicContact CE2-CD2 4.12Å; F154-W223 AromaticContact CE2-CE2 3.32Å; F154-W223 HydrophobicContact CE2-CE3 4.49Å; F154-W223 AromaticContact CE2-CH2 3.39Å; F154-W223 HydrophobicContact CE2-CH2 3.39Å; F154-W223 AromaticContact CE2-CZ2 2.94Å; F154-W223 HydrophobicContact CE2-CZ2 2.94Å; F154-W223 HydrophobicContact CE2-CZ3 4.17Å; F154-W223 AromaticContact CE2-NE1 3.88Å; F154-W223 AromaticContact CZ-CE2 3.82Å; F154-W223 HydrophobicContact CZ-CH2 4.45Å; F154-W223 AromaticContact CZ-CZ2 3.63Å; F154-W223 HydrophobicContact CZ-CZ2 3.63Å; F154-W223 AromaticContact CZ-NE1 3.92Å
155	S	90.3	Very high	86	Confident	1 Å²	1	30.7 Å²	30.7	1%	0.007	14%	0.14	C	C	.	.	H	α-helix	trans	-64.1	-53.2	178.7	-154	0	0	0	0	110	S152 L153 S157 Y158 I159 D208 R214	S152-S155 WeakPolarHBondContact O-CB 3.36Å; S152-S155 PolarHBondContact O-N 3.35Å; L153-S155 VanDerWaalsContact C-N 3.34Å; S155-S157 VanDerWaalsContact C-N 3.35Å; S155-S157 PolarHBondContact O-N 2.89Å; S155-Y158 PolarHBondContact O-N 3.47Å; S155-I159 WeakPolarHBondContact O-CD1 3.21Å; S155-I159 VanDerWaalsContact O-CG1 3.28Å; S155-I159 WeakPolarHBondContact O-CG1 3.41Å; S155-I159 PolarHBondContact O-N 2.83Å; S155-D208 VanDerWaalsContact CB-OD2 3.29Å; S155-D208 WeakPolarHBondContact CB-OD2 3.36Å; S155-D208 PolarHBondContact OG-OD2 3.49Å; S155-R214 VanDerWaalsContact CB-CZ 3.49Å; S155-R214 PolarHBondContact OG-NH2 3.17Å
156	F	94	Very high	87.9	Confident	39 Å²	39	28.2 Å²	28.2	17%	0.171	13%	0.133	C	C	.	.	H	α-helix	trans	-53.7	-52.4	-179.8	176.7	-92.5	0	0	0	111.8	I90 S152 Y158 I159 S160 W198 V201 L202 S205	I90-F156 HydrophobicContact CD1-CE1 4.05Å; I90-F156 HydrophobicContact CG2-CD1 4.33Å; S152-F156 PolarHBondContact O-N 3.43Å; S152-F156 VanDerWaalsContact O-N 3.13Å; F156-Y158 PolarHBondContact O-N 2.88Å; F156-I159 PolarHBondContact O-N 3.29Å; F156-S160 VanDerWaalsContact O-CB 3.23Å; F156-S160 WeakPolarHBondContact O-CB 3.49Å; F156-S160 PolarHBondContact O-N 2.73Å; F156-W198 HydrophobicContact CE1-CE3 4.45Å; F156-W198 HydrophobicContact CE1-CH2 4.42Å; F156-W198 AromaticContact CE1-CZ3 3.63Å; F156-W198 HydrophobicContact CE1-CZ3 3.63Å; F156-W198 HydrophobicContact CE2-CE3 4.45Å; F156-W198 HydrophobicContact CE2-CZ3 4.36Å; F156-W198 AromaticContact CZ-CE3 3.76Å; F156-W198 HydrophobicContact CZ-CE3 3.76Å; F156-W198 HydrophobicContact CZ-CH2 4.47Å; F156-W198 AromaticContact CZ-CZ3 3.38Å; F156-W198 HydrophobicContact CZ-CZ3 3.38Å; F156-V201 HydrophobicContact CD2-CG1 3.79Å; F156-V201 HydrophobicContact CE2-CG1 3.77Å; F156-V201 HydrophobicContact CG-CG1 4.35Å; F156-V201 HydrophobicContact CZ-CG1 4.33Å; F156-V201 WeakPolarHBondContact O-CG1 3.45Å; F156-L202 HydrophobicContact CE2-CD1 4.31Å; F156-S205 WeakPolarHBondContact CA-OG 3.19Å; F156-S205 WeakPolarHBondContact CD2-OG 3.31Å
157	S	94.5	Very high	89.2	Confident	0 Å²	0	25.5 Å²	25.5	0%	0	12%	0.119	C	C	.	.	H	α-helix	trans	-69.2	-37.4	-176.1	-50.5	0	0	0	0	111.8	I90 Y91 L153 S155 S160 M161	I90-S157 WeakPolarHBondContact CB-OG 3.31Å; I90-S157 WeakPolarHBondContact CG2-OG 3.17Å; Y91-S157 PolarHBondContact N-OG 3.22Å; L153-S157 WeakPolarHBondContact O-CB 3.2Å; L153-S157 PolarHBondContact O-N 2.9Å; L153-S157 PolarHBondContact O-OG 3.4Å; S155-S157 VanDerWaalsContact C-N 3.35Å; S155-S157 PolarHBondContact O-N 2.89Å; S157-S160 WeakPolarHBondContact O-CB 3.38Å; S157-S160 PolarHBondContact O-N 3.18Å; S157-M161 WeakPolarHBondContact O-CB 3.46Å; S157-M161 VanDerWaalsContact O-CG 3.22Å; S157-M161 WeakPolarHBondContact O-CG 3.47Å; S157-M161 PolarHBondContact O-N 3.49Å
158	Y	92.5	Very high	90.2	Very high	18 Å²	18	24.6 Å²	24.6	7%	0.071	11%	0.114	C	C	.	.	H	α-helix	trans	-64.8	-47.3	176	177.9	-111	0	0	0	112.5	F154 S155 F156 S160 M161 L162 T245 L357	F154-Y158 WeakPolarHBondContact O-CB 3.48Å; F154-Y158 PolarHBondContact O-N 3.33Å; S155-Y158 PolarHBondContact O-N 3.47Å; F156-Y158 PolarHBondContact O-N 2.88Å; Y158-S160 VanDerWaalsContact C-N 3.28Å; Y158-S160 PolarHBondContact O-N 2.94Å; Y158-M161 PolarHBondContact O-N 2.84Å; Y158-L162 WeakPolarHBondContact O-CB 3.2Å; Y158-L162 PolarHBondContact O-N 2.8Å; Y158-T245 HydrophobicContact CE1-CG2 3.68Å; Y158-L357 HydrophobicContact CD2-CD2 4.41Å; Y158-L357 HydrophobicContact CE2-CD2 3.72Å
159	I	94	Very high	91	Very high	6 Å²	6	20.9 Å²	20.9	3%	0.031	10%	0.099	C	C	.	.	H	α-helix	trans	-63	-41.2	177.2	-64.6	157.8	0	0	0	109.5	S155 F156 L162 Y163 V201 I204	S155-I159 WeakPolarHBondContact O-CD1 3.21Å; S155-I159 VanDerWaalsContact O-CG1 3.28Å; S155-I159 WeakPolarHBondContact O-CG1 3.41Å; S155-I159 PolarHBondContact O-N 2.83Å; F156-I159 PolarHBondContact O-N 3.29Å; I159-L162 PolarHBondContact O-N 3.1Å; I159-Y163 HydrophobicContact CG2-CD1 3.94Å; I159-Y163 HydrophobicContact CG2-CE1 3.77Å; I159-Y163 HydrophobicContact CG2-CG 4.47Å; I159-Y163 WeakPolarHBondContact O-CB 3.13Å; I159-Y163 VanDerWaalsContact O-CD1 3.22Å; I159-Y163 WeakPolarHBondContact O-CD1 3.48Å; I159-Y163 PolarHBondContact O-N 3.33Å; I159-V201 HydrophobicContact CB-CG1 4.42Å; I159-V201 HydrophobicContact CG2-CB 4.45Å; I159-V201 HydrophobicContact CG2-CG1 4.29Å; I159-V201 HydrophobicContact CG2-CG2 4.15Å; I159-I204 HydrophobicContact CD1-CB 4.4Å; I159-I204 HydrophobicContact CD1-CG2 3.47Å; I159-I204 VanDerWaalsContact CD1-CG2 3.47Å; I159-I204 HydrophobicContact CG1-CG2 4.31Å; I159-I204 HydrophobicContact CG2-CG2 4.23Å
160	S	96	Very high	91.9	Very high	0 Å²	0	18.9 Å²	18.9	0%	0	9%	0.093	C	C	.	.	H	α-helix	trans	-59.4	-50.4	175.1	-166	0	0	0	0	112.4	S87 F156 S157 Y158 L162 Y163 F164 W198	S87-S160 WeakPolarHBondContact OG-CB 3.29Å; S87-S160 PolarHBondContact OG-OG 3.37Å; F156-S160 VanDerWaalsContact O-CB 3.23Å; F156-S160 WeakPolarHBondContact O-CB 3.49Å; F156-S160 PolarHBondContact O-N 2.73Å; S157-S160 WeakPolarHBondContact O-CB 3.38Å; S157-S160 PolarHBondContact O-N 3.18Å; Y158-S160 VanDerWaalsContact C-N 3.28Å; Y158-S160 PolarHBondContact O-N 2.94Å; S160-L162 VanDerWaalsContact C-N 3.27Å; S160-L162 PolarHBondContact O-N 3.06Å; S160-Y163 PolarHBondContact O-N 3.45Å; S160-F164 VanDerWaalsContact O-CD2 3.27Å; S160-F164 WeakPolarHBondContact O-CD2 3.39Å; S160-F164 PolarHBondContact O-N 2.66Å; S160-F164 WeakPolarHBondContact OG-CD2 3.29Å; S160-F164 WeakPolarHBondContact OG-CE2 3.23Å; S160-W198 WeakPolarHBondContact OG-CH2 3.49Å; S160-W198 WeakPolarHBondContact OG-CZ3 3.22Å
161	M	94.2	Very high	92.5	Very high	14 Å²	14	16.2 Å²	16.2	7%	0.069	8%	0.081	C	C	.	.	H	α-helix	trans	-55.3	-45	175.8	-75.2	171.5	66.1	0	0	111.1	L84 N88 Y91 S157 Y158 S165 V394	L84-M161 WeakPolarHBondContact CD2-O 3.13Å; N88-M161 WeakPolarHBondContact OD1-CE 3.49Å; N88-M161 PolarHBondContact OD1-SD 2.95Å; N88-M161 VanDerWaalsContact OD1-SD 3.42Å; Y91-M161 HydrophobicContact CD2-SD 3.99Å; Y91-M161 HydrophobicContact CG-SD 4.02Å; S157-M161 WeakPolarHBondContact O-CB 3.46Å; S157-M161 VanDerWaalsContact O-CG 3.22Å; S157-M161 WeakPolarHBondContact O-CG 3.47Å; S157-M161 PolarHBondContact O-N 3.49Å; Y158-M161 PolarHBondContact O-N 2.84Å; M161-S165 WeakPolarHBondContact O-CB 3.17Å; M161-S165 PolarHBondContact O-N 3.35Å; M161-S165 PolarHBondContact O-OG 2.89Å; M161-V394 HydrophobicContact CE-CG1 4.37Å
162	L	93.2	Very high	92.9	Very high	1 Å²	1	16.7 Å²	16.7	1%	0.005	8%	0.083	C	C	.	.	H	α-helix	trans	-63	-47.2	179	-178.2	62.5	0	0	0	111.6	Y158 I159 S160 S165 F166 T245 L248 P249 L357	Y158-L162 WeakPolarHBondContact O-CB 3.2Å; Y158-L162 PolarHBondContact O-N 2.8Å; I159-L162 PolarHBondContact O-N 3.1Å; S160-L162 VanDerWaalsContact C-N 3.27Å; S160-L162 PolarHBondContact O-N 3.06Å; L162-S165 PolarHBondContact O-N 3.4Å; L162-F166 PolarHBondContact O-N 2.95Å; L162-T245 HydrophobicContact CD2-CG2 4.4Å; L162-L248 HydrophobicContact CD1-CB 3.88Å; L162-L248 HydrophobicContact CD2-CB 4.06Å; L162-L248 HydrophobicContact CD2-CD1 3.65Å; L162-L248 HydrophobicContact CD2-CG 4.48Å; L162-L248 HydrophobicContact CG-CB 4.04Å; L162-L248 HydrophobicContact CG-CD1 3.77Å; L162-P249 HydrophobicContact CD1-CG 3.79Å; L162-L357 HydrophobicContact CD1-CD1 3.83Å
163	Y	96.2	Very high	93.3	Very high	30 Å²	30	16.8 Å²	16.8	12%	0.118	8%	0.079	C	C	.	.	H	α-helix	trans	-70.3	-42.8	-175.7	-82.7	37.4	0	0	0	112.1	I159 S160 S165 F166 L167 V197 V201 I204 W244 L248	I159-Y163 HydrophobicContact CG2-CD1 3.94Å; I159-Y163 HydrophobicContact CG2-CE1 3.77Å; I159-Y163 HydrophobicContact CG2-CG 4.47Å; I159-Y163 WeakPolarHBondContact O-CB 3.13Å; I159-Y163 VanDerWaalsContact O-CD1 3.22Å; I159-Y163 WeakPolarHBondContact O-CD1 3.48Å; I159-Y163 PolarHBondContact O-N 3.33Å; S160-Y163 PolarHBondContact O-N 3.45Å; Y163-S165 VanDerWaalsContact C-N 3.32Å; Y163-F166 PolarHBondContact O-N 3.36Å; Y163-L167 WeakPolarHBondContact O-CB 3.37Å; Y163-L167 PolarHBondContact O-N 3.38Å; Y163-V197 HydrophobicContact CD2-CG1 4.18Å; Y163-V197 HydrophobicContact CG-CG1 4.5Å; Y163-V201 HydrophobicContact CD2-CG2 3.93Å; Y163-V201 HydrophobicContact CG-CG2 4.1Å; Y163-I204 HydrophobicContact CE2-CD1 4.07Å; Y163-I204 WeakPolarHBondContact OH-CD1 3.22Å; Y163-W244 HydrophobicContact CE1-CZ2 4.27Å; Y163-W244 AromaticContact CE1-NE1 3.23Å; Y163-W244 AromaticContact CZ-CE2 4Å; Y163-W244 AromaticContact CZ-CZ2 3.94Å; Y163-W244 AromaticContact CZ-NE1 3.42Å; Y163-W244 VanDerWaalsContact OH-CE2 3.23Å; Y163-W244 VanDerWaalsContact OH-CZ2 3.27Å; Y163-W244 WeakPolarHBondContact OH-CZ2 3.33Å; Y163-W244 PolarHBondContact OH-NE1 2.98Å; Y163-L248 HydrophobicContact CD1-CD1 3.93Å; Y163-L248 HydrophobicContact CE1-CD1 3.64Å
164	F	95.8	Very high	93.5	Very high	0 Å²	0	15.1 Å²	15.1	0%	0	7%	0.071	C	C	.	.	H	α-helix	trans	-72.2	-28.6	176.4	-73.9	-64.4	0	0	0	112.4	Q83 L84 S160 L167 L168 I194 V197 W198	Q83-F164 HydrophobicContact CB-CB 4.41Å; Q83-F164 HydrophobicContact CB-CD1 3.54Å; Q83-F164 HydrophobicContact CB-CD2 3.7Å; Q83-F164 HydrophobicContact CB-CE1 3.61Å; Q83-F164 HydrophobicContact CB-CE2 3.76Å; Q83-F164 HydrophobicContact CB-CG 3.6Å; Q83-F164 HydrophobicContact CB-CZ 3.72Å; Q83-F164 HydrophobicContact CG-CD1 3.89Å; Q83-F164 HydrophobicContact CG-CE1 3.56Å; Q83-F164 HydrophobicContact CG-CE2 4.37Å; Q83-F164 HydrophobicContact CG-CG 4.44Å; Q83-F164 HydrophobicContact CG-CZ 3.83Å; L84-F164 HydrophobicContact CD2-CB 3.67Å; L84-F164 HydrophobicContact CG-CB 3.79Å; S160-F164 VanDerWaalsContact O-CD2 3.27Å; S160-F164 WeakPolarHBondContact O-CD2 3.39Å; S160-F164 PolarHBondContact O-N 2.66Å; S160-F164 WeakPolarHBondContact OG-CD2 3.29Å; S160-F164 WeakPolarHBondContact OG-CE2 3.23Å; F164-L167 HydrophobicContact CD1-CD2 4.06Å; F164-L167 HydrophobicContact CE1-CD2 4.27Å; F164-L167 PolarHBondContact O-N 3.35Å; F164-L168 WeakPolarHBondContact O-CB 3.39Å; F164-L168 PolarHBondContact O-N 3.31Å; F164-I194 HydrophobicContact CE1-CG1 4.43Å; F164-I194 HydrophobicContact CE1-CG2 4.13Å; F164-I194 HydrophobicContact CZ-CG2 4.33Å; F164-V197 HydrophobicContact CD1-CG1 4.08Å; F164-V197 HydrophobicContact CD2-CG1 4.34Å; F164-V197 HydrophobicContact CE1-CB 4.06Å; F164-V197 HydrophobicContact CE1-CG1 3.62Å; F164-V197 HydrophobicContact CE2-CG1 3.92Å; F164-V197 HydrophobicContact CG-CG1 4.4Å; F164-V197 HydrophobicContact CZ-CB 4.12Å; F164-V197 HydrophobicContact CZ-CG1 3.53Å; F164-W198 HydrophobicContact CD2-CZ2 4.49Å; F164-W198 AromaticContact CE2-CD2 3.78Å; F164-W198 HydrophobicContact CE2-CD2 3.78Å; F164-W198 AromaticContact CE2-CE2 3.46Å; F164-W198 VanDerWaalsContact CE2-CE2 3.46Å; F164-W198 HydrophobicContact CE2-CE3 4.15Å; F164-W198 HydrophobicContact CE2-CG 4.34Å; F164-W198 AromaticContact CE2-CH2 3.97Å; F164-W198 HydrophobicContact CE2-CH2 3.97Å; F164-W198 AromaticContact CE2-CZ2 3.58Å; F164-W198 HydrophobicContact CE2-CZ2 3.58Å; F164-W198 HydrophobicContact CE2-CZ3 4.22Å; F164-W198 AromaticContact CE2-NE1 3.84Å; F164-W198 AromaticContact CZ-CD1 3.66Å; F164-W198 AromaticContact CZ-CD2 3.86Å; F164-W198 HydrophobicContact CZ-CD2 3.86Å; F164-W198 AromaticContact CZ-CE2 3.53Å; F164-W198 AromaticContact CZ-CG 3.95Å; F164-W198 HydrophobicContact CZ-CG 3.95Å; F164-W198 HydrophobicContact CZ-CZ2 4.08Å; F164-W198 AromaticContact CZ-NE1 3.4Å
165	S	93.6	Very high	93.5	Very high	8 Å²	8	16.7 Å²	16.7	6%	0.056	9%	0.085	C	C	.	.	H	α-helix	trans	-66.9	-44.3	171.4	-62.3	0	0	0	0	110.1	L84 M161 L162 Y163 L167 L168 T169 M252	L84-S165 WeakPolarHBondContact CD2-OG 3.27Å; M161-S165 WeakPolarHBondContact O-CB 3.17Å; M161-S165 PolarHBondContact O-N 3.35Å; M161-S165 PolarHBondContact O-OG 2.89Å; L162-S165 PolarHBondContact O-N 3.4Å; Y163-S165 VanDerWaalsContact C-N 3.32Å; S165-L167 VanDerWaalsContact C-N 3.34Å; S165-L167 PolarHBondContact O-N 2.9Å; S165-L168 WeakPolarHBondContact O-CB 3.28Å; S165-L168 PolarHBondContact O-N 3.22Å; S165-T169 PolarHBondContact O-N 3.4Å; S165-T169 PolarHBondContact O-OG1 3.44Å; S165-M252 VanDerWaalsContact CB-CE 3.47Å
166	F	94.7	Very high	93.3	Very high	56 Å²	56	18.6 Å²	18.6	25%	0.246	9%	0.093	C	C	.	.	H	α-helix	trans	-59.4	-44.9	172.7	175	-102.9	0	0	0	111.7	L162 Y163 L168 T169 L170 L248 I251 M252 M255	L162-F166 PolarHBondContact O-N 2.95Å; Y163-F166 PolarHBondContact O-N 3.36Å; F166-L168 VanDerWaalsContact C-N 3.3Å; F166-L168 PolarHBondContact O-N 3.28Å; F166-T169 WeakPolarHBondContact O-CB 3.22Å; F166-T169 PolarHBondContact O-N 3.1Å; F166-T169 VanDerWaalsContact O-N 3.14Å; F166-L170 HydrophobicContact CE1-CD2 4.37Å; F166-L170 WeakPolarHBondContact O-CB 3.41Å; F166-L170 PolarHBondContact O-N 2.79Å; F166-L248 HydrophobicContact CD2-CD2 4.14Å; F166-L248 HydrophobicContact CG-CD2 4.19Å; F166-I251 HydrophobicContact CE2-CG2 3.82Å; F166-M252 HydrophobicContact CB-CG 4.17Å; F166-M252 HydrophobicContact CB-SD 3.93Å; F166-M252 HydrophobicContact CD2-CG 3.8Å; F166-M252 HydrophobicContact CG-CG 4.49Å; F166-M255 HydrophobicContact CE2-SD 3.95Å
167	L	95.4	Very high	93.2	Very high	5 Å²	5	19.2 Å²	19.2	3%	0.026	10%	0.098	C	C	.	.	H	α-helix	trans	-62	-38.5	178.1	-177.2	60.5	0	0	0	112.3	I80 Y163 F164 S165 L170 N171 F185 L193 I194 V197	I80-L167 HydrophobicContact CD1-CD2 4.29Å; I80-L167 HydrophobicContact CD1-CG 3.99Å; I80-L167 HydrophobicContact CG1-CD2 4.05Å; I80-L167 HydrophobicContact CG1-CG 4.24Å; I80-L167 HydrophobicContact CG2-CG 4.49Å; Y163-L167 WeakPolarHBondContact O-CB 3.37Å; Y163-L167 PolarHBondContact O-N 3.38Å; F164-L167 HydrophobicContact CD1-CD2 4.06Å; F164-L167 HydrophobicContact CE1-CD2 4.27Å; F164-L167 PolarHBondContact O-N 3.35Å; S165-L167 VanDerWaalsContact C-N 3.34Å; S165-L167 PolarHBondContact O-N 2.9Å; L167-L170 PolarHBondContact O-N 3.29Å; L167-N171 WeakPolarHBondContact O-CB 3.38Å; L167-N171 PolarHBondContact O-N 3.11Å; L167-F185 HydrophobicContact CD1-CE1 4.04Å; L167-L193 HydrophobicContact CD1-CD2 3.38Å; L167-L193 HydrophobicContact CD1-CG 4.05Å; L167-L193 HydrophobicContact CD2-CD2 4.37Å; L167-L193 HydrophobicContact CG-CD2 4.49Å; L167-I194 HydrophobicContact CD2-CG1 4.29Å; L167-V197 HydrophobicContact CD2-CG2 4.36Å
168	L	93	Very high	93.2	Very high	5 Å²	5	22.6 Å²	22.6	3%	0.026	12%	0.116	C	C	.	.	H	α-helix	trans	-63.1	-43.9	173.9	-174.3	63.8	0	0	0	111.3	F77 I80 L84 F164 S165 F166 N171 R172	F77-L168 HydrophobicContact CD2-CD1 3.56Å; F77-L168 HydrophobicContact CE2-CD1 3.84Å; F77-L168 HydrophobicContact CE2-CD2 4.43Å; I80-L168 HydrophobicContact CB-CD1 4.35Å; I80-L168 HydrophobicContact CG2-CB 3.79Å; I80-L168 HydrophobicContact CG2-CD1 4.06Å; L84-L168 HydrophobicContact CD1-CB 4.49Å; L84-L168 HydrophobicContact CD1-CD2 3.86Å; F164-L168 WeakPolarHBondContact O-CB 3.39Å; F164-L168 PolarHBondContact O-N 3.31Å; S165-L168 WeakPolarHBondContact O-CB 3.28Å; S165-L168 PolarHBondContact O-N 3.22Å; F166-L168 VanDerWaalsContact C-N 3.3Å; F166-L168 PolarHBondContact O-N 3.28Å; L168-N171 PolarHBondContact O-N 3.16Å; L168-R172 WeakPolarHBondContact O-CG 3.47Å; L168-R172 PolarHBondContact O-N 3.17Å
169	T	92.7	Very high	93.2	Very high	0 Å²	0	25.5 Å²	25.5	0%	0	14%	0.137	C	C	.	.	H	α-helix	trans	-61.8	-44.8	175	-54	0	0	0	0	111.3	S165 F166 R172 F173 M252 M255 Y256	S165-T169 PolarHBondContact O-N 3.4Å; S165-T169 PolarHBondContact O-OG1 3.44Å; F166-T169 WeakPolarHBondContact O-CB 3.22Å; F166-T169 PolarHBondContact O-N 3.1Å; F166-T169 VanDerWaalsContact O-N 3.14Å; T169-R172 PolarHBondContact O-N 3.45Å; T169-F173 WeakPolarHBondContact O-CB 3.42Å; T169-F173 PolarHBondContact O-N 3.29Å; T169-M252 HydrophobicContact CG2-CB 4.22Å; T169-M252 HydrophobicContact CG2-CG 4.37Å; T169-M252 WeakPolarHBondContact OG1-CE 3.44Å; T169-M255 HydrophobicContact CG2-CB 3.7Å; T169-M255 HydrophobicContact CG2-CE 4.1Å; T169-M255 HydrophobicContact CG2-CG 4.48Å; T169-M255 HydrophobicContact CG2-SD 4.01Å; T169-Y256 WeakPolarHBondContact CA-OH 3.34Å; T169-Y256 WeakPolarHBondContact CB-OH 3.43Å; T169-Y256 HydrophobicContact CG2-CD2 4.02Å; T169-Y256 HydrophobicContact CG2-CE1 4.12Å; T169-Y256 HydrophobicContact CG2-CE2 3.47Å; T169-Y256 VanDerWaalsContact CG2-CE2 3.47Å; T169-Y256 VanDerWaalsContact CG2-CZ 3.49Å; T169-Y256 WeakPolarHBondContact OG1-CE2 3.48Å; T169-Y256 PolarHBondContact OG1-OH 2.94Å
170	L	94.6	Very high	93.1	Very high	55 Å²	55	34.6 Å²	34.6	29%	0.288	18%	0.176	S	C	.	.	H	α-helix	trans	-63.7	-42.5	178.1	-175.7	65.1	0	0	0	112.3	F166 L167 R172 F173 V174 F185 M255	F166-L170 HydrophobicContact CE1-CD2 4.37Å; F166-L170 WeakPolarHBondContact O-CB 3.41Å; F166-L170 PolarHBondContact O-N 2.79Å; L167-L170 PolarHBondContact O-N 3.29Å; L170-R172 VanDerWaalsContact C-N 3.29Å; L170-R172 PolarHBondContact O-N 3.08Å; L170-F173 PolarHBondContact O-N 3.3Å; L170-V174 HydrophobicContact CD1-CG2 4.38Å; L170-V174 WeakPolarHBondContact O-CB 3.28Å; L170-V174 WeakPolarHBondContact O-CG2 3.42Å; L170-V174 PolarHBondContact O-N 2.77Å; L170-F185 HydrophobicContact CD2-CZ 4.47Å; L170-F185 HydrophobicContact CG-CZ 4.22Å; L170-M255 HydrophobicContact CB-CE 4.12Å; L170-M255 HydrophobicContact CD1-CE 3.74Å
171	N	92.2	Very high	93	Very high	9 Å²	9	42 Å²	42	5%	0.048	21%	0.205	C	C	.	.	H	α-helix	trans	-55	-46.8	174	171.8	-108.2	0	0	0	111.6	I80 L167 L168 V174 A175 F185	I80-N171 HydrophobicContact CD1-CB 3.91Å; L167-N171 WeakPolarHBondContact O-CB 3.38Å; L167-N171 PolarHBondContact O-N 3.11Å; L168-N171 PolarHBondContact O-N 3.16Å; N171-V174 PolarHBondContact O-N 3.18Å; N171-A175 WeakPolarHBondContact O-CB 3.31Å; N171-A175 PolarHBondContact O-N 3.02Å; N171-F185 HydrophobicContact CB-CD1 3.82Å; N171-F185 HydrophobicContact CB-CE1 3.6Å; N171-F185 HydrophobicContact CB-CG 4.38Å; N171-F185 HydrophobicContact CB-CZ 3.99Å; N171-F185 WeakPolarHBondContact ND2-CB 3.44Å; N171-F185 WeakPolarHBondContact ND2-CD1 3.39Å; N171-F185 WeakPolarHBondContact ND2-CG 3.36Å
172	R	90.5	Very high	92.8	Very high	11 Å²	11	43.2 Å²	43.2	4%	0.042	21%	0.212	C	C	.	.	H	α-helix	trans	-68.5	-44.6	179	-68.7	171.9	177.6	-172.2	-7.5	111.9	L168 T169 L170 V174 A175 F176 I259 V346	L168-R172 WeakPolarHBondContact O-CG 3.47Å; L168-R172 PolarHBondContact O-N 3.17Å; T169-R172 PolarHBondContact O-N 3.45Å; L170-R172 VanDerWaalsContact C-N 3.29Å; L170-R172 PolarHBondContact O-N 3.08Å; R172-V174 VanDerWaalsContact C-N 3.26Å; R172-V174 PolarHBondContact O-N 2.95Å; R172-A175 WeakPolarHBondContact O-CB 3.44Å; R172-A175 PolarHBondContact O-N 3.35Å; R172-F176 HydrophobicContact CB-CD2 4.39Å; R172-F176 HydrophobicContact CB-CE2 4.42Å; R172-F176 WeakPolarHBondContact O-CD2 3.26Å; R172-F176 PolarHBondContact O-N 3.05Å; R172-I259 HydrophobicContact CB-CD1 4.14Å; R172-V346 VanDerWaalsContact NE-CG1 3.33Å; R172-V346 VanDerWaalsContact NH1-C 3.33Å; R172-V346 VanDerWaalsContact NH1-CG1 3.3Å; R172-V346 PolarHBondContact NH1-O 3.43Å
173	F	92.6	Very high	92.7	Very high	40 Å²	40	46.3 Å²	46.3	18%	0.175	24%	0.238	C	C	.	.	H	α-helix	trans	-55.7	-45.4	176.2	-175	-89.6	0	0	0	111.1	T169 L170 F176 I177 L178 M255 V258 I259	T169-F173 WeakPolarHBondContact O-CB 3.42Å; T169-F173 PolarHBondContact O-N 3.29Å; L170-F173 PolarHBondContact O-N 3.3Å; F173-F176 PolarHBondContact O-N 2.93Å; F173-I177 HydrophobicContact CD1-CB 4.37Å; F173-I177 HydrophobicContact CD2-CG1 3.87Å; F173-I177 HydrophobicContact CE1-CB 4.12Å; F173-I177 HydrophobicContact CE1-CG1 4.44Å; F173-I177 HydrophobicContact CE1-CG2 4.21Å; F173-I177 HydrophobicContact CE2-CB 4.32Å; F173-I177 HydrophobicContact CE2-CG1 3.79Å; F173-I177 HydrophobicContact CE2-CG2 4.45Å; F173-I177 HydrophobicContact CG-CG1 4.25Å; F173-I177 HydrophobicContact CZ-CB 4.1Å; F173-I177 HydrophobicContact CZ-CG1 4.08Å; F173-I177 HydrophobicContact CZ-CG2 3.94Å; F173-I177 VanDerWaalsContact O-CB 3.27Å; F173-I177 WeakPolarHBondContact O-CB 3.09Å; F173-I177 PolarHBondContact O-N 2.85Å; F173-L178 HydrophobicContact CD1-CD1 4.33Å; F173-L178 HydrophobicContact CE1-CD1 3.83Å; F173-L178 HydrophobicContact CE1-CG 4.18Å; F173-M255 HydrophobicContact CB-CE 3.38Å; F173-M255 HydrophobicContact CD1-CE 4.14Å; F173-M255 HydrophobicContact CD2-CB 3.93Å; F173-M255 HydrophobicContact CD2-CE 4.01Å; F173-M255 HydrophobicContact CD2-CG 4.08Å; F173-M255 HydrophobicContact CE2-CG 4.42Å; F173-M255 HydrophobicContact CG-CE 3.59Å; F173-V258 HydrophobicContact CE2-CB 4.04Å; F173-V258 HydrophobicContact CE2-CG1 3.73Å; F173-V258 HydrophobicContact CZ-CG1 4.41Å; F173-I259 HydrophobicContact CB-CD1 4.05Å; F173-I259 HydrophobicContact CB-CG1 4.39Å; F173-I259 HydrophobicContact CD2-CD1 4.39Å; F173-I259 HydrophobicContact CD2-CG1 4.07Å
174	V	93.1	Very high	92.4	Very high	13 Å²	13	48.8 Å²	48.8	8%	0.079	25%	0.249	C	C	.	.	H	α-helix	trans	-64.6	-39.9	175.3	169.9	0	0	0	0	111.8	L170 N171 R172 F176 L178 P179 F185	L170-V174 HydrophobicContact CD1-CG2 4.38Å; L170-V174 WeakPolarHBondContact O-CB 3.28Å; L170-V174 WeakPolarHBondContact O-CG2 3.42Å; L170-V174 PolarHBondContact O-N 2.77Å; N171-V174 PolarHBondContact O-N 3.18Å; R172-V174 VanDerWaalsContact C-N 3.26Å; R172-V174 PolarHBondContact O-N 2.95Å; V174-F176 PolarHBondContact O-N 3.03Å; V174-L178 CarbonylContact O-C 3.58Å; V174-L178 WeakPolarHBondContact O-CA 3.4Å; V174-L178 PolarHBondContact O-N 3.24Å; V174-L178 VanDerWaalsContact O-O 3.04Å; V174-P179 WeakPolarHBondContact O-CA 3.44Å; V174-F185 HydrophobicContact CB-CD2 4.23Å; V174-F185 HydrophobicContact CB-CE2 3.82Å; V174-F185 HydrophobicContact CG1-CD2 4.01Å; V174-F185 HydrophobicContact CG1-CE2 3.99Å; V174-F185 HydrophobicContact CG2-CE2 3.91Å
175	A	89.9	Confident	92.1	Very high	40 Å²	40	49.1 Å²	49.1	33%	0.331	25%	0.251	S	S	.	.	H	α-helix	trans	-62.4	-41.1	176.7	0	0	0	0	0	113	N171 R172	N171-A175 WeakPolarHBondContact O-CB 3.31Å; N171-A175 PolarHBondContact O-N 3.02Å; R172-A175 WeakPolarHBondContact O-CB 3.44Å; R172-A175 PolarHBondContact O-N 3.35Å
176	F	87.4	Confident	91.8	Very high	41 Å²	41	56.4 Å²	56.4	18%	0.18	28%	0.281	C	S	.	.	H	α-helix	trans	-90.1	-43.5	-174	-71.8	-66.5	0	0	0	114.6	R172 F173 V174 I259 I263 K266 E343	R172-F176 HydrophobicContact CB-CD2 4.39Å; R172-F176 HydrophobicContact CB-CE2 4.42Å; R172-F176 WeakPolarHBondContact O-CD2 3.26Å; R172-F176 PolarHBondContact O-N 3.05Å; F173-F176 PolarHBondContact O-N 2.93Å; V174-F176 PolarHBondContact O-N 3.03Å; F176-I259 HydrophobicContact CB-CG2 4.27Å; F176-I259 HydrophobicContact CD2-CG2 3.67Å; F176-I259 HydrophobicContact CE2-CG2 4.35Å; F176-I259 HydrophobicContact CG-CG2 4.04Å; F176-I263 HydrophobicContact CD1-CD1 4.37Å; F176-I263 HydrophobicContact CD1-CG1 4.21Å; F176-I263 HydrophobicContact CE1-CD1 4.35Å; F176-I263 HydrophobicContact CE1-CG1 4.46Å; F176-K266 PolarHBondContact O-NZ 3.15Å; F176-E343 HydrophobicContact CE1-CG 3.94Å; F176-E343 VanDerWaalsContact CE1-OE1 3.29Å; F176-E343 WeakPolarHBondContact CE1-OE1 3.35Å; F176-E343 HydrophobicContact CZ-CG 3.72Å
177	I	91.6	Very high	91.3	Very high	52 Å²	52	55.8 Å²	55.8	27%	0.267	28%	0.284	S	S	.	.	T	Hydrogen-bonded Turn	trans	-97	-39.9	-170.7	-50.5	-57.5	0	0	0	111	F173 P179 V258 I259 S262	F173-I177 HydrophobicContact CD1-CB 4.37Å; F173-I177 HydrophobicContact CD2-CG1 3.87Å; F173-I177 HydrophobicContact CE1-CB 4.12Å; F173-I177 HydrophobicContact CE1-CG1 4.44Å; F173-I177 HydrophobicContact CE1-CG2 4.21Å; F173-I177 HydrophobicContact CE2-CB 4.32Å; F173-I177 HydrophobicContact CE2-CG1 3.79Å; F173-I177 HydrophobicContact CE2-CG2 4.45Å; F173-I177 HydrophobicContact CG-CG1 4.25Å; F173-I177 HydrophobicContact CZ-CB 4.1Å; F173-I177 HydrophobicContact CZ-CG1 4.08Å; F173-I177 HydrophobicContact CZ-CG2 3.94Å; F173-I177 VanDerWaalsContact O-CB 3.27Å; F173-I177 WeakPolarHBondContact O-CB 3.09Å; F173-I177 PolarHBondContact O-N 2.85Å; I177-P179 WeakPolarHBondContact O-CD 3.18Å; I177-V258 HydrophobicContact CD1-CG1 3.87Å; I177-V258 HydrophobicContact CG1-CG1 4.08Å; I177-I259 HydrophobicContact CG1-CG1 4.43Å; I177-S262 WeakPolarHBondContact CD1-OG 3.14Å
178	L	94	Very high	91.2	Very high	71 Å²	71	64.5 Å²	64.5	37%	0.372	32%	0.321	S	S	.	.			trans	-124.5	54.5	-170.5	-62.7	179.8	0	0	0	112.5	F173 V174 K180 Y181	F173-L178 HydrophobicContact CD1-CD1 4.33Å; F173-L178 HydrophobicContact CE1-CD1 3.83Å; F173-L178 HydrophobicContact CE1-CG 4.18Å; V174-L178 CarbonylContact O-C 3.58Å; V174-L178 WeakPolarHBondContact O-CA 3.4Å; V174-L178 PolarHBondContact O-N 3.24Å; V174-L178 VanDerWaalsContact O-O 3.04Å; L178-K180 PolarHBondContact O-N 3.44Å; L178-Y181 HydrophobicContact CB-CD2 3.88Å; L178-Y181 PolarHBondContact O-N 2.96Å
179	P	91.6	Very high	91.2	Very high	79 Å²	79	71.6 Å²	71.6	51%	0.513	35%	0.348	S	S	.	.	G	3₁₀ helix	trans	-60.1	-24.8	-169.2	24.3	-35.4	0	0	0	113.8	V174 I177 Y181 N182	V174-P179 WeakPolarHBondContact O-CA 3.44Å; I177-P179 WeakPolarHBondContact O-CD 3.18Å; P179-Y181 PolarHBondContact O-N 2.96Å; P179-N182 WeakPolarHBondContact O-CB 3.11Å; P179-N182 PolarHBondContact O-N 2.78Å
180	K	93.1	Very high	91.3	Very high	196 Å²	196	71.7 Å²	71.7	85%	0.852	35%	0.348	S	S	*	.	G	3₁₀ helix	trans	-56	-30.1	173.7	-65.8	-174.7	178.5	-177.6	0	112.9	L178	L178-K180 PolarHBondContact O-N 3.44Å
181	Y	93.5	Very high	91.4	Very high	155 Å²	155	74.1 Å²	74.1	61%	0.608	36%	0.355	S	S	*	.	G	3₁₀ helix	trans	-94.8	3	-179.1	-57.8	-87.1	0	0	0	113.2	L178 P179 A183 F184	L178-Y181 HydrophobicContact CB-CD2 3.88Å; L178-Y181 PolarHBondContact O-N 2.96Å; P179-Y181 PolarHBondContact O-N 2.96Å; Y181-A183 PolarHBondContact O-N 3.3Å; Y181-A183 VanDerWaalsContact O-N 3.14Å; Y181-F184 VanDerWaalsContact O-CB 3.25Å; Y181-F184 WeakPolarHBondContact O-CB 3.32Å; Y181-F184 PolarHBondContact O-N 2.91Å
182	N	90.7	Very high	91.6	Very high	41 Å²	41	81.1 Å²	81.1	22%	0.219	39%	0.385	C	S	.	.	T	Hydrogen-bonded Turn	trans	-63	-22	179.5	-164.8	18.7	0	0	0	112.7	P179 F184 F185 K186	P179-N182 WeakPolarHBondContact O-CB 3.11Å; P179-N182 PolarHBondContact O-N 2.78Å; N182-F184 PolarHBondContact O-N 3.46Å; N182-F184 VanDerWaalsContact O-N 3.11Å; N182-F185 PolarHBondContact O-N 3.26Å; N182-K186 PolarHBondContact O-N 3.46Å
183	A	90.9	Very high	91.8	Very high	66 Å²	66	82 Å²	82	55%	0.545	39%	0.39	S	S	.	.	H	α-helix	trans	-54	-29	171.2	0	0	0	0	0	112.8	Y181 F185 K186 S187	Y181-A183 PolarHBondContact O-N 3.3Å; Y181-A183 VanDerWaalsContact O-N 3.14Å; A183-F185 PolarHBondContact O-N 3.27Å; A183-K186 PolarHBondContact O-N 2.96Å; A183-S187 WeakPolarHBondContact O-CB 3.24Å; A183-S187 PolarHBondContact O-N 2.92Å; A183-S187 PolarHBondContact O-OG 3.06Å
184	F	88.6	Confident	92.1	Very high	82 Å²	82	80.8 Å²	80.8	36%	0.36	39%	0.385	S	S	.	.	H	α-helix	trans	-61.6	-44.3	176.6	-164	-106.6	0	0	0	111.9	Y181 N182 S187 R189 L193	Y181-F184 VanDerWaalsContact O-CB 3.25Å; Y181-F184 WeakPolarHBondContact O-CB 3.32Å; Y181-F184 PolarHBondContact O-N 2.91Å; N182-F184 PolarHBondContact O-N 3.46Å; N182-F184 VanDerWaalsContact O-N 3.11Å; F184-S187 PolarHBondContact O-OG 3.34Å; F184-R189 HydrophobicContact CD2-CB 4.22Å; F184-R189 HydrophobicContact CE2-CB 4.09Å; F184-L193 HydrophobicContact CD1-CD2 4.38Å; F184-L193 HydrophobicContact CE1-CD1 4.27Å; F184-L193 HydrophobicContact CE1-CD2 3.73Å; F184-L193 HydrophobicContact CE1-CG 4.42Å
185	F	89.8	Confident	92.3	Very high	7 Å²	7	82.4 Å²	82.4	3%	0.031	40%	0.4	C	S	.	.	H	α-helix	trans	-81.5	-17.2	-178.2	-70.8	-82	0	0	0	114.3	A76 L167 L170 N171 V174 N182 A183 L190 L193	A76-F185 HydrophobicContact CB-CB 4.07Å; L167-F185 HydrophobicContact CD1-CE1 4.04Å; L170-F185 HydrophobicContact CD2-CZ 4.47Å; L170-F185 HydrophobicContact CG-CZ 4.22Å; N171-F185 HydrophobicContact CB-CD1 3.82Å; N171-F185 HydrophobicContact CB-CE1 3.6Å; N171-F185 HydrophobicContact CB-CG 4.38Å; N171-F185 HydrophobicContact CB-CZ 3.99Å; N171-F185 WeakPolarHBondContact ND2-CB 3.44Å; N171-F185 WeakPolarHBondContact ND2-CD1 3.39Å; N171-F185 WeakPolarHBondContact ND2-CG 3.36Å; V174-F185 HydrophobicContact CB-CD2 4.23Å; V174-F185 HydrophobicContact CB-CE2 3.82Å; V174-F185 HydrophobicContact CG1-CD2 4.01Å; V174-F185 HydrophobicContact CG1-CE2 3.99Å; V174-F185 HydrophobicContact CG2-CE2 3.91Å; N182-F185 PolarHBondContact O-N 3.26Å; A183-F185 PolarHBondContact O-N 3.27Å; F185-L190 HydrophobicContact CD1-CD1 3.94Å; F185-L190 HydrophobicContact CE1-CD1 4.45Å; F185-L193 HydrophobicContact CE1-CD2 4.21Å
186	K	87.4	Confident	92.6	Very high	161 Å²	161	85.9 Å²	85.9	70%	0.7	41%	0.408	S	S	*	.	H	α-helix	trans	-87.3	-15	176.8	-68.3	-173.9	177.3	-174.2	0	114	N182 A183	N182-K186 PolarHBondContact O-N 3.46Å; A183-K186 PolarHBondContact O-N 2.96Å
187	S	85	Confident	93.1	Very high	42 Å²	42	84.7 Å²	84.7	29%	0.294	40%	0.404	S	S	.	.	S	Bend	trans	-98.9	175.5	-168.8	71.9	0	0	0	0	113.5	A183 F184 R189 L190	A183-S187 WeakPolarHBondContact O-CB 3.24Å; A183-S187 PolarHBondContact O-N 2.92Å; A183-S187 PolarHBondContact O-OG 3.06Å; F184-S187 PolarHBondContact O-OG 3.34Å; S187-R189 PolarHBondContact O-N 2.94Å; S187-R189 WeakPolarHBondContact OG-CB 3.5Å; S187-R189 WeakPolarHBondContact OG-CD 3.31Å; S187-R189 WeakPolarHBondContact OG-CG 3.49Å; S187-R189 PolarHBondContact OG-N 3.19Å; S187-L190 PolarHBondContact O-N 3.29Å; S187-L190 VanDerWaalsContact O-N 3.08Å
188	K	92.8	Very high	93.5	Very high	189 Å²	189	84.6 Å²	84.6	82%	0.822	40%	0.4	S	S	*	.	T	Hydrogen-bonded Turn	trans	-52.4	-20.7	168.2	-64.6	-179.6	-178.9	178.6	0	112.8	L190 Y191	K188-L190 PolarHBondContact O-N 3.47Å; K188-Y191 PolarHBondContact O-N 3.38Å
189	R	94.3	Very high	93.6	Very high	153 Å²	153	86.6 Å²	86.6	58%	0.577	41%	0.411	S	S	*	.	H	α-helix	trans	-62.7	-27.9	177.6	-57.3	174.3	-179.3	176.5	-0.5	112.9	F184 S187 Y191 F192 L193	F184-R189 HydrophobicContact CD2-CB 4.22Å; F184-R189 HydrophobicContact CE2-CB 4.09Å; S187-R189 PolarHBondContact O-N 2.94Å; S187-R189 WeakPolarHBondContact OG-CB 3.5Å; S187-R189 WeakPolarHBondContact OG-CD 3.31Å; S187-R189 WeakPolarHBondContact OG-CG 3.49Å; S187-R189 PolarHBondContact OG-N 3.19Å; R189-Y191 VanDerWaalsContact C-N 3.33Å; R189-Y191 PolarHBondContact O-N 2.94Å; R189-F192 PolarHBondContact O-N 2.94Å; R189-L193 WeakPolarHBondContact O-CB 3.46Å; R189-L193 PolarHBondContact O-N 3.16Å
190	L	94.7	Very high	93.9	Very high	3 Å²	3	84.2 Å²	84.2	2%	0.016	40%	0.396	C	S	.	.	H	α-helix	trans	-62.6	-40.2	175.9	177.7	61	0	0	0	112.1	A76 L79 I80 F185 S187 K188 L193 I194	A76-L190 HydrophobicContact CB-CD2 3.71Å; L79-L190 HydrophobicContact CB-CD2 4.42Å; L79-L190 HydrophobicContact CD1-CD2 3.86Å; I80-L190 HydrophobicContact CD1-CD1 4.35Å; I80-L190 HydrophobicContact CG1-CD1 4.42Å; F185-L190 HydrophobicContact CD1-CD1 3.94Å; F185-L190 HydrophobicContact CE1-CD1 4.45Å; S187-L190 PolarHBondContact O-N 3.29Å; S187-L190 VanDerWaalsContact O-N 3.08Å; K188-L190 PolarHBondContact O-N 3.47Å; L190-L193 HydrophobicContact CD1-CD2 4.41Å; L190-L193 WeakPolarHBondContact O-CB 3.23Å; L190-L193 PolarHBondContact O-N 3.43Å; L190-I194 HydrophobicContact CD1-CD1 4.18Å; L190-I194 HydrophobicContact CD1-CG1 4.28Å; L190-I194 HydrophobicContact CG-CD1 4.03Å; L190-I194 WeakPolarHBondContact O-CG1 3.23Å; L190-I194 PolarHBondContact O-N 3.18Å
191	Y	95.5	Very high	94.1	Very high	106 Å²	106	74.9 Å²	74.9	42%	0.416	36%	0.355	S	S	.	.	H	α-helix	trans	-65.3	-41.9	177.3	-70.3	-80.9	0	0	0	111.6	R75 L79 K188 R189 L193 I194 A195	R75-Y191 PolarHBondContact NE-OH 3.42Å; R75-Y191 PolarHBondContact NH2-OH 2.88Å; L79-Y191 HydrophobicContact CD1-CE1 3.92Å; L79-Y191 HydrophobicContact CD1-CE2 4.21Å; L79-Y191 HydrophobicContact CD2-CE1 4.17Å; K188-Y191 PolarHBondContact O-N 3.38Å; R189-Y191 VanDerWaalsContact C-N 3.33Å; R189-Y191 PolarHBondContact O-N 2.94Å; Y191-L193 VanDerWaalsContact C-N 3.31Å; Y191-L193 PolarHBondContact O-N 2.88Å; Y191-I194 PolarHBondContact O-N 3.46Å; Y191-A195 WeakPolarHBondContact O-CB 3.23Å; Y191-A195 PolarHBondContact O-N 2.89Å
192	F	95.9	Very high	94.2	Very high	155 Å²	155	71.3 Å²	71.3	68%	0.68	35%	0.347	S	S	*	.	H	α-helix	trans	-60	-42.9	173.7	-179.3	-95.3	0	0	0	111.5	R189 A195 F196	R189-F192 PolarHBondContact O-N 2.94Å; F192-A195 PolarHBondContact O-N 2.69Å; F192-F196 WeakPolarHBondContact O-CB 3.48Å; F192-F196 PolarHBondContact O-N 3.22Å
193	L	96.2	Very high	94.4	Very high	30 Å²	30	71.9 Å²	71.9	16%	0.157	36%	0.357	C	S	.	.	H	α-helix	trans	-64	-43.4	176.9	-174.7	69.1	0	0	0	112.4	L167 F184 F185 R189 L190 Y191 F196 V197	L167-L193 HydrophobicContact CD1-CD2 3.38Å; L167-L193 HydrophobicContact CD1-CG 4.05Å; L167-L193 HydrophobicContact CD2-CD2 4.37Å; L167-L193 HydrophobicContact CG-CD2 4.49Å; F184-L193 HydrophobicContact CD1-CD2 4.38Å; F184-L193 HydrophobicContact CE1-CD1 4.27Å; F184-L193 HydrophobicContact CE1-CD2 3.73Å; F184-L193 HydrophobicContact CE1-CG 4.42Å; F185-L193 HydrophobicContact CE1-CD2 4.21Å; R189-L193 WeakPolarHBondContact O-CB 3.46Å; R189-L193 PolarHBondContact O-N 3.16Å; L190-L193 HydrophobicContact CD1-CD2 4.41Å; L190-L193 WeakPolarHBondContact O-CB 3.23Å; L190-L193 PolarHBondContact O-N 3.43Å; Y191-L193 VanDerWaalsContact C-N 3.31Å; Y191-L193 PolarHBondContact O-N 2.88Å; L193-F196 PolarHBondContact O-N 3.48Å; L193-V197 WeakPolarHBondContact O-CG2 3.34Å; L193-V197 PolarHBondContact O-N 3.24Å
194	I	97.2	Very high	94.6	Very high	14 Å²	14	70.5 Å²	70.5	7%	0.072	34%	0.34	C	S	.	.	H	α-helix	trans	-61.5	-45	175.3	-72	168.9	0	0	0	110.5	L79 Q83 F164 L167 L190 Y191 F196 V197 W198	L79-I194 HydrophobicContact CB-CD1 4Å; Q83-I194 HydrophobicContact CG-CG2 3.93Å; F164-I194 HydrophobicContact CE1-CG1 4.43Å; F164-I194 HydrophobicContact CE1-CG2 4.13Å; F164-I194 HydrophobicContact CZ-CG2 4.33Å; L167-I194 HydrophobicContact CD2-CG1 4.29Å; L190-I194 HydrophobicContact CD1-CD1 4.18Å; L190-I194 HydrophobicContact CD1-CG1 4.28Å; L190-I194 HydrophobicContact CG-CD1 4.03Å; L190-I194 WeakPolarHBondContact O-CG1 3.23Å; L190-I194 PolarHBondContact O-N 3.18Å; Y191-I194 PolarHBondContact O-N 3.46Å; I194-F196 VanDerWaalsContact C-N 3.34Å; I194-F196 PolarHBondContact O-N 2.8Å; I194-V197 PolarHBondContact O-N 2.92Å; I194-W198 VanDerWaalsContact O-CD1 3.3Å; I194-W198 PolarHBondContact O-N 3.49Å
195	A	97.5	Very high	94.8	Very high	48 Å²	48	67.2 Å²	67.2	40%	0.397	33%	0.327	S	S	.	.	H	α-helix	trans	-61.9	-42.7	176.2	0	0	0	0	0	111.7	Y191 F192 V197 W198 L199	Y191-A195 WeakPolarHBondContact O-CB 3.23Å; Y191-A195 PolarHBondContact O-N 2.89Å; F192-A195 PolarHBondContact O-N 2.69Å; A195-V197 PolarHBondContact O-N 3.28Å; A195-W198 PolarHBondContact O-N 3.45Å; A195-L199 WeakPolarHBondContact O-CG 3.29Å; A195-L199 PolarHBondContact O-N 3.02Å
196	F	97.4	Very high	94.9	Very high	113 Å²	113	71.2 Å²	71.2	50%	0.496	35%	0.348	S	S	.	.	H	α-helix	trans	-61.7	-42.5	176	178.3	-97.9	0	0	0	112.3	F192 L193 I194 L199 S200	F192-F196 WeakPolarHBondContact O-CB 3.48Å; F192-F196 PolarHBondContact O-N 3.22Å; L193-F196 PolarHBondContact O-N 3.48Å; I194-F196 VanDerWaalsContact C-N 3.34Å; I194-F196 PolarHBondContact O-N 2.8Å; F196-L199 PolarHBondContact O-N 3.31Å; F196-S200 WeakPolarHBondContact O-CB 3.39Å; F196-S200 PolarHBondContact O-N 3.26Å; F196-S200 PolarHBondContact O-OG 2.9Å
197	V	98.1	Very high	95.1	Very high	15 Å²	15	66 Å²	66	9%	0.091	33%	0.329	C	S	.	.	H	α-helix	trans	-61.2	-46.9	174.4	168.2	0	0	0	0	110.5	Y163 F164 L167 L193 I194 A195 L199 S200 V201	Y163-V197 HydrophobicContact CD2-CG1 4.18Å; Y163-V197 HydrophobicContact CG-CG1 4.5Å; F164-V197 HydrophobicContact CD1-CG1 4.08Å; F164-V197 HydrophobicContact CD2-CG1 4.34Å; F164-V197 HydrophobicContact CE1-CB 4.06Å; F164-V197 HydrophobicContact CE1-CG1 3.62Å; F164-V197 HydrophobicContact CE2-CG1 3.92Å; F164-V197 HydrophobicContact CG-CG1 4.4Å; F164-V197 HydrophobicContact CZ-CB 4.12Å; F164-V197 HydrophobicContact CZ-CG1 3.53Å; L167-V197 HydrophobicContact CD2-CG2 4.36Å; L193-V197 WeakPolarHBondContact O-CG2 3.34Å; L193-V197 PolarHBondContact O-N 3.24Å; I194-V197 PolarHBondContact O-N 2.92Å; A195-V197 PolarHBondContact O-N 3.28Å; V197-L199 PolarHBondContact O-N 3Å; V197-S200 WeakPolarHBondContact O-CB 3.11Å; V197-S200 PolarHBondContact O-N 3.06Å; V197-V201 HydrophobicContact CG1-CG2 4.31Å; V197-V201 VanDerWaalsContact O-CG2 3.23Å; V197-V201 WeakPolarHBondContact O-CG2 3.46Å; V197-V201 PolarHBondContact O-N 2.92Å
198	W	98.4	Very high	95.4	Very high	50 Å²	50	64.1 Å²	64.1	19%	0.189	32%	0.316	C	S	.	.	H	α-helix	trans	-60.2	-43.8	176.2	-83.4	121.8	0	0	0	113.2	Q83 I86 F156 S160 F164 I194 A195 S200 V201 L202	Q83-W198 HydrophobicContact CB-CZ2 4.39Å; I86-W198 HydrophobicContact CG2-CH2 4.25Å; I86-W198 HydrophobicContact CG2-CZ2 4.26Å; F156-W198 HydrophobicContact CE1-CE3 4.45Å; F156-W198 HydrophobicContact CE1-CH2 4.42Å; F156-W198 AromaticContact CE1-CZ3 3.63Å; F156-W198 HydrophobicContact CE1-CZ3 3.63Å; F156-W198 HydrophobicContact CE2-CE3 4.45Å; F156-W198 HydrophobicContact CE2-CZ3 4.36Å; F156-W198 AromaticContact CZ-CE3 3.76Å; F156-W198 HydrophobicContact CZ-CE3 3.76Å; F156-W198 HydrophobicContact CZ-CH2 4.47Å; F156-W198 AromaticContact CZ-CZ3 3.38Å; F156-W198 HydrophobicContact CZ-CZ3 3.38Å; S160-W198 WeakPolarHBondContact OG-CH2 3.49Å; S160-W198 WeakPolarHBondContact OG-CZ3 3.22Å; F164-W198 HydrophobicContact CD2-CZ2 4.49Å; F164-W198 AromaticContact CE2-CD2 3.78Å; F164-W198 HydrophobicContact CE2-CD2 3.78Å; F164-W198 AromaticContact CE2-CE2 3.46Å; F164-W198 VanDerWaalsContact CE2-CE2 3.46Å; F164-W198 HydrophobicContact CE2-CE3 4.15Å; F164-W198 HydrophobicContact CE2-CG 4.34Å; F164-W198 AromaticContact CE2-CH2 3.97Å; F164-W198 HydrophobicContact CE2-CH2 3.97Å; F164-W198 AromaticContact CE2-CZ2 3.58Å; F164-W198 HydrophobicContact CE2-CZ2 3.58Å; F164-W198 HydrophobicContact CE2-CZ3 4.22Å; F164-W198 AromaticContact CE2-NE1 3.84Å; F164-W198 AromaticContact CZ-CD1 3.66Å; F164-W198 AromaticContact CZ-CD2 3.86Å; F164-W198 HydrophobicContact CZ-CD2 3.86Å; F164-W198 AromaticContact CZ-CE2 3.53Å; F164-W198 AromaticContact CZ-CG 3.95Å; F164-W198 HydrophobicContact CZ-CG 3.95Å; F164-W198 HydrophobicContact CZ-CZ2 4.08Å; F164-W198 AromaticContact CZ-NE1 3.4Å; I194-W198 VanDerWaalsContact O-CD1 3.3Å; I194-W198 PolarHBondContact O-N 3.49Å; A195-W198 PolarHBondContact O-N 3.45Å; W198-S200 VanDerWaalsContact C-N 3.3Å; W198-S200 PolarHBondContact O-N 3.2Å; W198-V201 PolarHBondContact O-N 3.43Å; W198-L202 WeakPolarHBondContact O-CB 3.3Å; W198-L202 PolarHBondContact O-N 3.41Å
199	L	97.8	Very high	95.2	Very high	114 Å²	114	60.4 Å²	60.4	60%	0.597	30%	0.3	S	S	*	.	H	α-helix	trans	-61.5	-40.5	175.9	-73.2	170.2	0	0	0	111.5	A195 F196 V197 L202 A203	A195-L199 WeakPolarHBondContact O-CG 3.29Å; A195-L199 PolarHBondContact O-N 3.02Å; F196-L199 PolarHBondContact O-N 3.31Å; V197-L199 PolarHBondContact O-N 3Å; L199-L202 PolarHBondContact O-N 2.87Å; L199-A203 WeakPolarHBondContact O-CB 3.32Å; L199-A203 PolarHBondContact O-N 2.88Å
200	S	97.8	Very high	94.9	Very high	28 Å²	28	57.6 Å²	57.6	20%	0.196	30%	0.303	C	S	.	.	H	α-helix	trans	-65.1	-45.7	176.5	-57.3	0	0	0	0	111.7	F196 V197 W198 L202 A203 I204	F196-S200 WeakPolarHBondContact O-CB 3.39Å; F196-S200 PolarHBondContact O-N 3.26Å; F196-S200 PolarHBondContact O-OG 2.9Å; V197-S200 WeakPolarHBondContact O-CB 3.11Å; V197-S200 PolarHBondContact O-N 3.06Å; W198-S200 VanDerWaalsContact C-N 3.3Å; W198-S200 PolarHBondContact O-N 3.2Å; S200-L202 VanDerWaalsContact C-N 3.31Å; S200-L202 PolarHBondContact O-N 3.39Å; S200-A203 PolarHBondContact O-N 3.44Å; S200-I204 VanDerWaalsContact O-CG1 3.27Å; S200-I204 WeakPolarHBondContact O-CG1 3.01Å; S200-I204 PolarHBondContact O-N 3.25Å
201	V	96.9	Very high	94.7	Very high	0 Å²	0	62 Å²	62	0%	0	32%	0.32	C	S	.	.	H	α-helix	trans	-58.4	-45	175.2	171.2	0	0	0	0	110.3	F156 I159 Y163 V197 W198 S205	F156-V201 HydrophobicContact CD2-CG1 3.79Å; F156-V201 HydrophobicContact CE2-CG1 3.77Å; F156-V201 HydrophobicContact CG-CG1 4.35Å; F156-V201 HydrophobicContact CZ-CG1 4.33Å; F156-V201 WeakPolarHBondContact O-CG1 3.45Å; I159-V201 HydrophobicContact CB-CG1 4.42Å; I159-V201 HydrophobicContact CG2-CB 4.45Å; I159-V201 HydrophobicContact CG2-CG1 4.29Å; I159-V201 HydrophobicContact CG2-CG2 4.15Å; Y163-V201 HydrophobicContact CD2-CG2 3.93Å; Y163-V201 HydrophobicContact CG-CG2 4.1Å; V197-V201 HydrophobicContact CG1-CG2 4.31Å; V197-V201 VanDerWaalsContact O-CG2 3.23Å; V197-V201 WeakPolarHBondContact O-CG2 3.46Å; V197-V201 PolarHBondContact O-N 2.92Å; W198-V201 PolarHBondContact O-N 3.43Å; V201-S205 VanDerWaalsContact O-CB 3.29Å; V201-S205 WeakPolarHBondContact O-CB 3.28Å; V201-S205 PolarHBondContact O-N 2.88Å; V201-S205 PolarHBondContact O-OG 3.46Å
202	L	95.3	Very high	94.4	Very high	81 Å²	81	57.1 Å²	57.1	42%	0.424	30%	0.302	S	S	.	.	H	α-helix	trans	-62.4	-48.2	178.6	-177.8	64.7	0	0	0	111.4	F156 W198 L199 S200 I204 S205 I206	F156-L202 HydrophobicContact CE2-CD1 4.31Å; W198-L202 WeakPolarHBondContact O-CB 3.3Å; W198-L202 PolarHBondContact O-N 3.41Å; L199-L202 PolarHBondContact O-N 2.87Å; S200-L202 VanDerWaalsContact C-N 3.31Å; S200-L202 PolarHBondContact O-N 3.39Å; L202-I204 PolarHBondContact O-N 2.83Å; L202-S205 PolarHBondContact O-N 3.38Å; L202-I206 HydrophobicContact CD1-CD1 4.24Å; L202-I206 HydrophobicContact CD1-CG1 4.46Å; L202-I206 HydrophobicContact CG-CD1 3.96Å; L202-I206 VanDerWaalsContact O-CG1 3.31Å; L202-I206 WeakPolarHBondContact O-CG1 3.35Å; L202-I206 PolarHBondContact O-N 2.66Å
203	A	96.1	Very high	94.1	Very high	53 Å²	53	53 Å²	53	44%	0.438	29%	0.289	S	S	.	.	H	α-helix	trans	-58.5	-48.1	178.6	0	0	0	0	0	111.9	L199 S200 S205 I206 V207	L199-A203 WeakPolarHBondContact O-CB 3.32Å; L199-A203 PolarHBondContact O-N 2.88Å; S200-A203 PolarHBondContact O-N 3.44Å; A203-S205 VanDerWaalsContact C-N 3.29Å; A203-S205 PolarHBondContact O-N 3.47Å; A203-I206 PolarHBondContact O-N 3.13Å; A203-V207 WeakPolarHBondContact O-CG2 3.29Å; A203-V207 PolarHBondContact O-N 2.92Å
204	I	94.9	Very high	93.7	Very high	37 Å²	37	52.7 Å²	52.7	19%	0.19	29%	0.286	C	S	.	.	H	α-helix	trans	-63.2	-37.5	177.8	-66.7	170.7	0	0	0	110.9	I159 Y163 S200 L202 V207 D208 W237	I159-I204 HydrophobicContact CD1-CB 4.4Å; I159-I204 HydrophobicContact CD1-CG2 3.47Å; I159-I204 VanDerWaalsContact CD1-CG2 3.47Å; I159-I204 HydrophobicContact CG1-CG2 4.31Å; I159-I204 HydrophobicContact CG2-CG2 4.23Å; Y163-I204 HydrophobicContact CE2-CD1 4.07Å; Y163-I204 WeakPolarHBondContact OH-CD1 3.22Å; S200-I204 VanDerWaalsContact O-CG1 3.27Å; S200-I204 WeakPolarHBondContact O-CG1 3.01Å; S200-I204 PolarHBondContact O-N 3.25Å; L202-I204 PolarHBondContact O-N 2.83Å; I204-V207 PolarHBondContact O-N 2.83Å; I204-D208 WeakPolarHBondContact O-CB 3.47Å; I204-D208 PolarHBondContact O-N 3.34Å; I204-W237 HydrophobicContact CB-CH2 4.3Å; I204-W237 HydrophobicContact CG2-CH2 3.62Å; I204-W237 HydrophobicContact CG2-CZ2 3.98Å; I204-W237 WeakPolarHBondContact O-CZ2 3.34Å
205	S	92.5	Very high	93.3	Very high	13 Å²	13	55.8 Å²	55.8	9%	0.091	30%	0.297	C	S	.	.	H	α-helix	trans	-69.9	-36.5	178.1	-57.5	0	0	0	0	112.6	F156 V201 L202 A203 D208 F209	F156-S205 WeakPolarHBondContact CA-OG 3.19Å; F156-S205 WeakPolarHBondContact CD2-OG 3.31Å; V201-S205 VanDerWaalsContact O-CB 3.29Å; V201-S205 WeakPolarHBondContact O-CB 3.28Å; V201-S205 PolarHBondContact O-N 2.88Å; V201-S205 PolarHBondContact O-OG 3.46Å; L202-S205 PolarHBondContact O-N 3.38Å; A203-S205 VanDerWaalsContact C-N 3.29Å; A203-S205 PolarHBondContact O-N 3.47Å; S205-D208 PolarHBondContact O-N 3.2Å; S205-F209 WeakPolarHBondContact O-CB 3.45Å; S205-F209 PolarHBondContact O-N 2.96Å
206	I	91.1	Very high	92.9	Very high	91 Å²	91	54 Å²	54	47%	0.467	28%	0.28	S	S	.	.	H	α-helix	trans	-64.7	-46.1	173.3	-69.8	166.1	0	0	0	109.7	L202 A203 D208 F209 C210	L202-I206 HydrophobicContact CD1-CD1 4.24Å; L202-I206 HydrophobicContact CD1-CG1 4.46Å; L202-I206 HydrophobicContact CG-CD1 3.96Å; L202-I206 VanDerWaalsContact O-CG1 3.31Å; L202-I206 WeakPolarHBondContact O-CG1 3.35Å; L202-I206 PolarHBondContact O-N 2.66Å; A203-I206 PolarHBondContact O-N 3.13Å; I206-D208 VanDerWaalsContact C-N 3.32Å; I206-D208 PolarHBondContact O-N 3.21Å; I206-F209 WeakPolarHBondContact O-CB 3.32Å; I206-F209 PolarHBondContact O-N 3.43Å; I206-F209 VanDerWaalsContact O-N 3.16Å; I206-C210 PolarHBondContact O-N 2.93Å; I206-C210 PolarHBondContact O-SG 3.18Å
207	V	91.7	Very high	92.5	Very high	50 Å²	50	49.7 Å²	49.7	30%	0.303	26%	0.262	S	S	.	.	H	α-helix	trans	-58.4	-46.2	175.5	174.1	0	0	0	0	110.7	A203 I204 F209 C210 Y211 W237	A203-V207 WeakPolarHBondContact O-CG2 3.29Å; A203-V207 PolarHBondContact O-N 2.92Å; I204-V207 PolarHBondContact O-N 2.83Å; V207-F209 VanDerWaalsContact C-N 3.31Å; V207-F209 PolarHBondContact O-N 3.2Å; V207-C210 PolarHBondContact O-N 3.14Å; V207-Y211 HydrophobicContact CG1-CD2 3.63Å; V207-Y211 HydrophobicContact CG1-CE2 3.74Å; V207-Y211 VanDerWaalsContact O-CD2 3.26Å; V207-Y211 WeakPolarHBondContact O-CD2 3.44Å; V207-Y211 PolarHBondContact O-N 3.35Å; V207-W237 HydrophobicContact CB-CH2 3.9Å; V207-W237 HydrophobicContact CB-CZ2 4.15Å; V207-W237 HydrophobicContact CB-CZ3 4.22Å; V207-W237 HydrophobicContact CG1-CD2 3.72Å; V207-W237 HydrophobicContact CG1-CE3 3.53Å; V207-W237 HydrophobicContact CG1-CG 4.49Å; V207-W237 HydrophobicContact CG1-CH2 3.58Å; V207-W237 HydrophobicContact CG1-CZ2 3.84Å; V207-W237 HydrophobicContact CG1-CZ3 3.46Å; V207-W237 VanDerWaalsContact CG1-CZ3 3.46Å
208	D	90.9	Very high	92	Very high	4 Å²	4	50.1 Å²	50.1	2%	0.021	26%	0.264	C	S	.	.	H	α-helix	trans	-60.5	-40.2	176.2	-164.7	68.8	0	0	0	112.5	S155 I204 S205 I206 C212 R214 W237 R241	S155-D208 VanDerWaalsContact CB-OD2 3.29Å; S155-D208 WeakPolarHBondContact CB-OD2 3.36Å; S155-D208 PolarHBondContact OG-OD2 3.49Å; I204-D208 WeakPolarHBondContact O-CB 3.47Å; I204-D208 PolarHBondContact O-N 3.34Å; S205-D208 PolarHBondContact O-N 3.2Å; I206-D208 VanDerWaalsContact C-N 3.32Å; I206-D208 PolarHBondContact O-N 3.21Å; D208-C212 WeakPolarHBondContact O-CA 3.34Å; D208-C212 WeakPolarHBondContact O-CB 3.39Å; D208-C212 PolarHBondContact O-N 3.47Å; D208-R214 IonicContact OD1-NH2 2.65Å; D208-R214 IonicContact OD2-CZ 3.29Å; D208-R214 IonicContact OD2-NE 3.98Å; D208-R214 IonicContact OD2-NH2 2.73Å; D208-R214 PolarHBondContact OD2-NH2 2.05Å; D208-W237 HydrophobicContact CB-CZ2 3.89Å; D208-W237 PolarHBondContact OD1-NE1 3.22Å; D208-R241 WeakPolarHBondContact OD1-CD 3.28Å; D208-R241 IonicContact OD1-CZ 3.46Å; D208-R241 IonicContact OD1-NE 3.04Å; D208-R241 IonicContact OD1-NH1 2.64Å; D208-R241 PolarHBondContact OD1-NH1 2.93Å; D208-R241 IonicContact OD2-NH1 3.54Å; D208-R241 PolarHBondContact OD2-NH1 3.01Å
209	F	88.8	Confident	91.4	Very high	110 Å²	110	51.5 Å²	51.5	48%	0.482	27%	0.269	S	S	.	.	H	α-helix	trans	-67.1	-36.6	176.6	178.6	-99.4	0	0	0	112.6	S205 I206 V207	S205-F209 WeakPolarHBondContact O-CB 3.45Å; S205-F209 PolarHBondContact O-N 2.96Å; I206-F209 WeakPolarHBondContact O-CB 3.32Å; I206-F209 PolarHBondContact O-N 3.43Å; I206-F209 VanDerWaalsContact O-N 3.16Å; V207-F209 VanDerWaalsContact C-N 3.31Å; V207-F209 PolarHBondContact O-N 3.2Å
210	C	89.3	Confident	90.9	Very high	94 Å²	94	47.4 Å²	47.4	64%	0.635	25%	0.247	S	C	*	.	H	α-helix	trans	-71.5	-36.1	178.3	-70.6	0	0	0	0	113	I206 V207	I206-C210 PolarHBondContact O-N 2.93Å; I206-C210 PolarHBondContact O-SG 3.18Å; V207-C210 PolarHBondContact O-N 3.14Å
211	Y	89.6	Confident	90.6	Very high	95 Å²	95	46.1 Å²	46.1	37%	0.373	24%	0.238	S	C	.	.	H	α-helix	trans	-94.5	-23.5	-176.7	-73.3	-66.2	0	0	0	114.4	V207 C227 A234 W237	V207-Y211 HydrophobicContact CG1-CD2 3.63Å; V207-Y211 HydrophobicContact CG1-CE2 3.74Å; V207-Y211 VanDerWaalsContact O-CD2 3.26Å; V207-Y211 WeakPolarHBondContact O-CD2 3.44Å; V207-Y211 PolarHBondContact O-N 3.35Å; Y211-C227 WeakPolarHBondContact O-CA 3.25Å; Y211-A234 HydrophobicContact CD1-CB 4.15Å; Y211-W237 HydrophobicContact CD2-CB 4.28Å; Y211-W237 HydrophobicContact CD2-CG 4.24Å; Y211-W237 HydrophobicContact CG-CB 4.43Å
212	C	90.1	Very high	90.3	Very high	5 Å²	5	48.4 Å²	48.4	3%	0.034	25%	0.253	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-133.3	129	-172.6	-60.8	0	0	0	0	111.5	D208 I225 C227	D208-C212 WeakPolarHBondContact O-CA 3.34Å; D208-C212 WeakPolarHBondContact O-CB 3.39Å; D208-C212 PolarHBondContact O-N 3.47Å; C212-I225 HydrophobicContact CB-CG2 4.15Å; C212-C227 HydrophobicContact CB-CB 4.12Å; C212-C227 WeakPolarHBondContact CB-SG 3.27Å; C212-C227 WeakPolarHBondContact SG-CB 3.45Å; C212-C227 CovalentContact SG-SG 2.05Å; C212-C227 PolarHBondContact SG-SG 3.11Å
213	T	87.9	Confident	90	Very high	69 Å²	69	47 Å²	47	42%	0.423	24%	0.242	S	C	.	.	E	Extended strand (participates in β ladder)	trans	-92	139.6	167.8	61.8	0	0	0	0	109.4	K226	T213-K226 PolarHBondContact N-O 2.96Å; T213-K226 PolarHBondContact O-N 3.34Å; T213-K226 PolarHBondContact OG1-O 3.46Å; T213-K226 VanDerWaalsContact OG1-O 3.06Å
214	R	88.7	Confident	89.6	Confident	23 Å²	23	47 Å²	47	9%	0.087	23%	0.232	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-124	134.4	177.1	-64.9	-169.8	-170.9	-176.9	5.3	110.1	Y148 S151 S155 D208 E224 I225	Y148-R214 WeakPolarHBondContact CD1-O 3.38Å; S151-R214 WeakPolarHBondContact CB-O 3.32Å; S151-R214 PolarHBondContact OG-O 3.01Å; S155-R214 VanDerWaalsContact CB-CZ 3.49Å; S155-R214 PolarHBondContact OG-NH2 3.17Å; D208-R214 IonicContact OD1-NH2 2.65Å; D208-R214 IonicContact OD2-CZ 3.29Å; D208-R214 IonicContact OD2-NE 3.98Å; D208-R214 IonicContact OD2-NH2 2.73Å; D208-R214 PolarHBondContact OD2-NH2 2.05Å; R214-E224 WeakPolarHBondContact CA-O 3.44Å; R214-I225 HydrophobicContact CG-CG1 4.2Å; R214-I225 HydrophobicContact CG-CG2 4.32Å
215	R	88.3	Confident	89.3	Confident	78 Å²	78	49 Å²	49	29%	0.294	24%	0.243	S	C	.	.	E	Extended strand (participates in β ladder)	trans	-136.1	144.4	173.3	63.8	-176.6	-176.1	171.1	6	110.2	Y148 L217 E224	Y148-R215 HydrophobicContact CE1-CB 4.04Å; R215-L217 HydrophobicContact CG-CD2 4.3Å; R215-E224 HydrophobicContact CG-CB 4.06Å; R215-E224 IonicContact CZ-OE2 3.06Å; R215-E224 PolarHBondContact N-O 2.97Å; R215-E224 IonicContact NE-OE2 4Å; R215-E224 PolarHBondContact NE-OE2 2.89Å; R215-E224 IonicContact NH2-OE1 2.7Å; R215-E224 PolarHBondContact NH2-OE1 3.28Å; R215-E224 IonicContact NH2-OE2 3.05Å; R215-E224 PolarHBondContact NH2-OE2 3.39Å; R215-E224 PolarHBondContact O-N 3.44Å
216	F	88.7	Confident	89.1	Confident	10 Å²	10	52.9 Å²	52.9	4%	0.044	26%	0.258	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-81	132.4	167.1	-165.8	-119	0	0	0	108.8	V98 I99 E102 L221 T222 W223	V98-F216 HydrophobicContact CG1-CB 4.16Å; I99-F216 HydrophobicContact CB-CE1 4.19Å; I99-F216 HydrophobicContact CB-CZ 4.21Å; I99-F216 HydrophobicContact CD1-CD2 4.03Å; I99-F216 HydrophobicContact CD1-CE1 4.47Å; I99-F216 HydrophobicContact CD1-CE2 3.59Å; I99-F216 HydrophobicContact CD1-CZ 3.83Å; I99-F216 HydrophobicContact CG1-CD1 3.96Å; I99-F216 HydrophobicContact CG1-CD2 3.96Å; I99-F216 HydrophobicContact CG1-CE1 3.73Å; I99-F216 HydrophobicContact CG1-CE2 3.71Å; I99-F216 HydrophobicContact CG1-CG 4.07Å; I99-F216 HydrophobicContact CG1-CZ 3.58Å; I99-F216 HydrophobicContact CG2-CE1 3.98Å; I99-F216 HydrophobicContact CG2-CZ 3.79Å; E102-F216 WeakPolarHBondContact OE2-CD1 3.18Å; F216-L221 HydrophobicContact CE1-CD2 3.96Å; F216-L221 VanDerWaalsContact CE2-C 3.49Å; F216-L221 WeakPolarHBondContact CE2-O 3.36Å; F216-L221 VanDerWaalsContact CZ-CA 3.46Å; F216-L221 HydrophobicContact CZ-CB 3.91Å; F216-L221 HydrophobicContact CZ-CD2 3.78Å; F216-L221 HydrophobicContact CZ-CG 4.49Å; F216-T222 WeakPolarHBondContact CD2-O 3.19Å; F216-W223 HydrophobicContact CB-CD2 4.49Å; F216-W223 HydrophobicContact CB-CE3 4.08Å; F216-W223 HydrophobicContact CB-CH2 3.56Å; F216-W223 HydrophobicContact CB-CZ2 3.95Å; F216-W223 HydrophobicContact CB-CZ3 3.58Å; F216-W223 AromaticContact CD2-CD2 3.79Å; F216-W223 HydrophobicContact CD2-CD2 3.79Å; F216-W223 AromaticContact CD2-CE2 3.39Å; F216-W223 HydrophobicContact CD2-CE3 4.22Å; F216-W223 HydrophobicContact CD2-CG 4.21Å; F216-W223 HydrophobicContact CD2-CH2 4.02Å; F216-W223 AromaticContact CD2-CZ2 3.48Å; F216-W223 HydrophobicContact CD2-CZ2 3.48Å; F216-W223 VanDerWaalsContact CD2-CZ2 3.48Å; F216-W223 HydrophobicContact CD2-CZ3 4.31Å; F216-W223 AromaticContact CD2-NE1 3.67Å; F216-W223 HydrophobicContact CE2-CZ2 4.24Å; F216-W223 AromaticContact CE2-NE1 3.84Å; F216-W223 HydrophobicContact CG-CH2 4.05Å; F216-W223 AromaticContact CG-CZ2 3.91Å; F216-W223 HydrophobicContact CG-CZ2 3.91Å; F216-W223 HydrophobicContact CG-CZ3 4.37Å
217	L	89.4	Confident	88.9	Confident	23 Å²	23	49.5 Å²	49.5	12%	0.12	24%	0.242	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-101.6	102.5	172.8	-66.8	-177.5	0	0	0	108	R215 W219 N220 L221 T222 E224	R215-L217 HydrophobicContact CG-CD2 4.3Å; L217-W219 VanDerWaalsContact C-N 3.3Å; L217-W219 HydrophobicContact CD1-CZ2 4.38Å; L217-W219 HydrophobicContact CD2-CZ2 4.09Å; L217-W219 PolarHBondContact O-N 2.73Å; L217-N220 WeakPolarHBondContact CB-OD1 3.29Å; L217-N220 PolarHBondContact O-N 3.43Å; L217-N220 PolarHBondContact O-OD1 2.67Å; L217-L221 WeakPolarHBondContact O-CA 3.27Å; L217-L221 PolarHBondContact O-N 2.76Å; L217-T222 PolarHBondContact N-O 2.85Å; L217-T222 PolarHBondContact O-N 2.69Å; L217-E224 HydrophobicContact CD1-CB 3.82Å; L217-E224 HydrophobicContact CD1-CG 4.38Å; L217-E224 WeakPolarHBondContact CD1-OE2 3.33Å; L217-E224 HydrophobicContact CG-CB 3.95Å
218	I	87.2	Confident	88.2	Confident	25 Å²	25	53.7 Å²	53.7	13%	0.128	26%	0.258	C	S	.	.	G	3₁₀ helix	trans	-59.2	-38.9	-177.9	-178.7	152.9	0	0	0	113.2	I30 R31 E102 N220 L221	I30-I218 HydrophobicContact CG2-CG1 4.16Å; I30-I218 WeakPolarHBondContact CG2-O 3.31Å; R31-I218 HydrophobicContact CG-CD1 4.48Å; R31-I218 HydrophobicContact CG-CG1 4.45Å; E102-I218 HydrophobicContact CB-CD1 3.74Å; E102-I218 WeakPolarHBondContact O-CD1 3.38Å; I218-N220 PolarHBondContact O-N 3.42Å; I218-L221 WeakPolarHBondContact O-CD2 3.34Å; I218-L221 PolarHBondContact O-N 3.34Å
219	W	85.7	Confident	87.3	Confident	78 Å²	78	61.3 Å²	61.3	30%	0.295	29%	0.294	S	S	.	.	G	3₁₀ helix	trans	-57.5	-27	-172.6	51.3	41.3	0	0	0	113.7	D29 I30 L217	D29-W219 HydrophobicContact CB-CB 4.14Å; I30-W219 PolarHBondContact N-O 3.02Å; I30-W219 VanDerWaalsContact N-O 3.17Å; L217-W219 VanDerWaalsContact C-N 3.3Å; L217-W219 HydrophobicContact CD1-CZ2 4.38Å; L217-W219 HydrophobicContact CD2-CZ2 4.09Å; L217-W219 PolarHBondContact O-N 2.73Å
220	N	88.6	Confident	86.1	Confident	28 Å²	28	67.3 Å²	67.3	15%	0.15	31%	0.314	C	S	.	.	G	3₁₀ helix	trans	-129.5	3.7	-176.6	64.7	1.6	0	0	0	112.3	L217 I218 T222 I380	L217-N220 WeakPolarHBondContact CB-OD1 3.29Å; L217-N220 PolarHBondContact O-N 3.43Å; L217-N220 PolarHBondContact O-OD1 2.67Å; I218-N220 PolarHBondContact O-N 3.42Å; N220-T222 HydrophobicContact CB-CG2 4.23Å; N220-T222 PolarHBondContact ND2-OG1 3.44Å; N220-T222 WeakPolarHBondContact O-CG2 3Å; N220-T222 PolarHBondContact O-N 3.19Å; N220-T222 WeakPolarHBondContact OD1-CB 3.21Å; N220-T222 PolarHBondContact OD1-N 3.47Å; N220-T222 PolarHBondContact OD1-OG1 3.05Å; N220-I380 HydrophobicContact CB-CG2 3.38Å
221	L	91.2	Very high	85.4	Confident	1 Å²	1	67.2 Å²	67.2	1%	0.005	31%	0.307	C	S	.	.	T	Hydrogen-bonded Turn	trans	53.1	36	-176.2	-52.9	174.8	0	0	0	113.4	I30 A42 F46 L103 F216 L217 I218 I385 N388	I30-L221 HydrophobicContact CD1-CD1 3.61Å; I30-L221 HydrophobicContact CD1-CD2 4.33Å; I30-L221 HydrophobicContact CD1-CG 4.03Å; A42-L221 HydrophobicContact CB-CD1 4.38Å; F46-L221 HydrophobicContact CE2-CD1 4.44Å; F46-L221 HydrophobicContact CZ-CD1 4.31Å; L103-L221 HydrophobicContact CD1-CD2 4.11Å; L103-L221 HydrophobicContact CD2-CD2 3.59Å; L103-L221 HydrophobicContact CG-CD2 3.88Å; F216-L221 HydrophobicContact CE1-CD2 3.96Å; F216-L221 VanDerWaalsContact CE2-C 3.49Å; F216-L221 WeakPolarHBondContact CE2-O 3.36Å; F216-L221 VanDerWaalsContact CZ-CA 3.46Å; F216-L221 HydrophobicContact CZ-CB 3.91Å; F216-L221 HydrophobicContact CZ-CD2 3.78Å; F216-L221 HydrophobicContact CZ-CG 4.49Å; L217-L221 WeakPolarHBondContact O-CA 3.27Å; L217-L221 PolarHBondContact O-N 2.76Å; I218-L221 WeakPolarHBondContact O-CD2 3.34Å; I218-L221 PolarHBondContact O-N 3.34Å; L221-I385 HydrophobicContact CD1-CG1 3.51Å; L221-N388 PolarHBondContact O-ND2 3.45Å
222	T	90.7	Very high	85.2	Confident	49 Å²	49	71.3 Å²	71.3	30%	0.301	33%	0.326	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-107.6	152.4	179.6	65.7	0	0	0	0	112.4	F216 L217 N220	F216-T222 WeakPolarHBondContact CD2-O 3.19Å; L217-T222 PolarHBondContact N-O 2.85Å; L217-T222 PolarHBondContact O-N 2.69Å; N220-T222 HydrophobicContact CB-CG2 4.23Å; N220-T222 PolarHBondContact ND2-OG1 3.44Å; N220-T222 WeakPolarHBondContact O-CG2 3Å; N220-T222 PolarHBondContact O-N 3.19Å; N220-T222 WeakPolarHBondContact OD1-CB 3.21Å; N220-T222 PolarHBondContact OD1-N 3.47Å; N220-T222 PolarHBondContact OD1-OG1 3.05Å
223	W	87.9	Confident	85	Confident	51 Å²	51	72.4 Å²	72.4	19%	0.193	34%	0.338	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-88.9	111.5	168.2	-72.9	95.1	0	0	0	109	V98 I99 S151 F154 F216	V98-W223 HydrophobicContact CG1-CH2 4.13Å; I99-W223 HydrophobicContact CD1-CZ2 3.51Å; I99-W223 HydrophobicContact CG1-CZ2 3.8Å; S151-W223 WeakPolarHBondContact OG-CZ3 3.48Å; F154-W223 HydrophobicContact CD2-CD2 4.29Å; F154-W223 AromaticContact CD2-CE2 3.92Å; F154-W223 HydrophobicContact CD2-CE3 4.45Å; F154-W223 AromaticContact CD2-CH2 3.9Å; F154-W223 HydrophobicContact CD2-CH2 3.9Å; F154-W223 AromaticContact CD2-CZ2 3.78Å; F154-W223 HydrophobicContact CD2-CZ2 3.78Å; F154-W223 HydrophobicContact CD2-CZ3 4.27Å; F154-W223 HydrophobicContact CE2-CD2 4.12Å; F154-W223 AromaticContact CE2-CE2 3.32Å; F154-W223 HydrophobicContact CE2-CE3 4.49Å; F154-W223 AromaticContact CE2-CH2 3.39Å; F154-W223 HydrophobicContact CE2-CH2 3.39Å; F154-W223 AromaticContact CE2-CZ2 2.94Å; F154-W223 HydrophobicContact CE2-CZ2 2.94Å; F154-W223 HydrophobicContact CE2-CZ3 4.17Å; F154-W223 AromaticContact CE2-NE1 3.88Å; F154-W223 AromaticContact CZ-CE2 3.82Å; F154-W223 HydrophobicContact CZ-CH2 4.45Å; F154-W223 AromaticContact CZ-CZ2 3.63Å; F154-W223 HydrophobicContact CZ-CZ2 3.63Å; F154-W223 AromaticContact CZ-NE1 3.92Å; F216-W223 HydrophobicContact CB-CD2 4.49Å; F216-W223 HydrophobicContact CB-CE3 4.08Å; F216-W223 HydrophobicContact CB-CH2 3.56Å; F216-W223 HydrophobicContact CB-CZ2 3.95Å; F216-W223 HydrophobicContact CB-CZ3 3.58Å; F216-W223 AromaticContact CD2-CD2 3.79Å; F216-W223 HydrophobicContact CD2-CD2 3.79Å; F216-W223 AromaticContact CD2-CE2 3.39Å; F216-W223 HydrophobicContact CD2-CE3 4.22Å; F216-W223 HydrophobicContact CD2-CG 4.21Å; F216-W223 HydrophobicContact CD2-CH2 4.02Å; F216-W223 AromaticContact CD2-CZ2 3.48Å; F216-W223 HydrophobicContact CD2-CZ2 3.48Å; F216-W223 VanDerWaalsContact CD2-CZ2 3.48Å; F216-W223 HydrophobicContact CD2-CZ3 4.31Å; F216-W223 AromaticContact CD2-NE1 3.67Å; F216-W223 HydrophobicContact CE2-CZ2 4.24Å; F216-W223 AromaticContact CE2-NE1 3.84Å; F216-W223 HydrophobicContact CG-CH2 4.05Å; F216-W223 AromaticContact CG-CZ2 3.91Å; F216-W223 HydrophobicContact CG-CZ2 3.91Å; F216-W223 HydrophobicContact CG-CZ3 4.37Å
224	E	88.3	Confident	85	Confident	52 Å²	52	69.2 Å²	69.2	24%	0.243	32%	0.319	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-89.3	128.3	172.2	-168.7	-178.7	-174.9	0	0	109.4	R214 R215 L217 K226	R214-E224 WeakPolarHBondContact CA-O 3.44Å; R215-E224 HydrophobicContact CG-CB 4.06Å; R215-E224 IonicContact CZ-OE2 3.06Å; R215-E224 PolarHBondContact N-O 2.97Å; R215-E224 IonicContact NE-OE2 4Å; R215-E224 PolarHBondContact NE-OE2 2.89Å; R215-E224 IonicContact NH2-OE1 2.7Å; R215-E224 PolarHBondContact NH2-OE1 3.28Å; R215-E224 IonicContact NH2-OE2 3.05Å; R215-E224 PolarHBondContact NH2-OE2 3.39Å; R215-E224 PolarHBondContact O-N 3.44Å; L217-E224 HydrophobicContact CD1-CB 3.82Å; L217-E224 HydrophobicContact CD1-CG 4.38Å; L217-E224 WeakPolarHBondContact CD1-OE2 3.33Å; L217-E224 HydrophobicContact CG-CB 3.95Å; E224-K226 VanDerWaalsContact CD-CE 3.41Å; E224-K226 HydrophobicContact CG-CG 4.24Å; E224-K226 WeakPolarHBondContact OE1-CE 3.32Å; E224-K226 IonicContact OE1-NZ 3.73Å
225	I	88.6	Confident	85	Confident	79 Å²	79	70.9 Å²	70.9	41%	0.405	33%	0.332	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-112.7	115	176.9	-52.1	178.6	0	0	0	106.5	C212 R214	C212-I225 HydrophobicContact CB-CG2 4.15Å; R214-I225 HydrophobicContact CG-CG1 4.2Å; R214-I225 HydrophobicContact CG-CG2 4.32Å
226	K	87.9	Confident	85.1	Confident	95 Å²	95	72.3 Å²	72.3	41%	0.413	34%	0.344	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-110.8	109.7	173.5	-65.1	-172.4	179.2	-167.3	0	108.8	T213 E224	T213-K226 PolarHBondContact N-O 2.96Å; T213-K226 PolarHBondContact O-N 3.34Å; T213-K226 PolarHBondContact OG1-O 3.46Å; T213-K226 VanDerWaalsContact OG1-O 3.06Å; E224-K226 VanDerWaalsContact CD-CE 3.41Å; E224-K226 HydrophobicContact CG-CG 4.24Å; E224-K226 WeakPolarHBondContact OE1-CE 3.32Å; E224-K226 IonicContact OE1-NZ 3.73Å
227	C	86.5	Confident	85.2	Confident	20 Å²	20	73.7 Å²	73.7	14%	0.135	35%	0.349	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-104.1	117.8	169	-47.8	0	0	0	0	106.1	Y211 C212 E229 A234	Y211-C227 WeakPolarHBondContact O-CA 3.25Å; C212-C227 HydrophobicContact CB-CB 4.12Å; C212-C227 WeakPolarHBondContact CB-SG 3.27Å; C212-C227 WeakPolarHBondContact SG-CB 3.45Å; C212-C227 CovalentContact SG-SG 2.05Å; C212-C227 PolarHBondContact SG-SG 3.11Å; C227-E229 PolarHBondContact O-N 3.5Å; C227-E229 VanDerWaalsContact O-N 3.11Å; C227-A234 HydrophobicContact CB-CB 4.22Å
228	E	78.8	Confident	85.2	Confident	138 Å²	138	77.9 Å²	77.9	65%	0.645	37%	0.368	S	S	*	.			trans	-65.3	113.8	-175.6	-76.7	-175.8	173.4	0	0	111	R230 N231 A234	E228-R230 PolarHBondContact O-N 3.16Å; E228-N231 PolarHBondContact O-N 3.3Å; E228-A234 WeakPolarHBondContact O-CB 3.18Å
229	E	70.3	Confident	85.3	Confident	164 Å²	164	79.6 Å²	79.6	77%	0.766	38%	0.383	S	S	*	.	T	Hydrogen-bonded Turn	trans	-63.5	-20.1	-178.6	-68	-177.7	174.9	0	0	114	C227 N231 T235	C227-E229 PolarHBondContact O-N 3.5Å; C227-E229 VanDerWaalsContact O-N 3.11Å; E229-N231 CarbonylContact O-C 3.5Å; E229-N231 PolarHBondContact O-N 2.89Å; E229-T235 HydrophobicContact CG-CG2 4.35Å
230	R	65.3	Low	85.6	Confident	237 Å²	237	79.5 Å²	79.5	89%	0.894	39%	0.391	S	S	*	.	T	Hydrogen-bonded Turn	trans	-54.4	-28.2	178.5	-78	-168.5	-164.9	-173.4	5.7	112.1	E228	E228-R230 PolarHBondContact O-N 3.16Å
231	N	74.3	Confident	85.7	Confident	92 Å²	92	80.4 Å²	80.4	49%	0.492	39%	0.392	S	S	.	.	S	Bend	trans	-96	111.4	175.4	-66.4	-24.7	0	0	0	109.3	E228 E229 G233 A234	E228-N231 PolarHBondContact O-N 3.3Å; E229-N231 CarbonylContact O-C 3.5Å; E229-N231 PolarHBondContact O-N 2.89Å; N231-G233 PolarHBondContact O-N 3.08Å; N231-A234 HydrophobicContact CB-CB 4.49Å; N231-A234 WeakPolarHBondContact O-CB 3.39Å; N231-A234 PolarHBondContact O-N 3.43Å
232	K	84.1	Confident	85.5	Confident	180 Å²	180	82.6 Å²	82.6	78%	0.783	40%	0.402	S	S	*	.	H	α-helix	trans	-47.9	-28.4	170.3	-71.1	-178.7	178.3	178.3	0	112.7	A234 T235 I236	K232-A234 PolarHBondContact O-N 3.06Å; K232-T235 PolarHBondContact O-OG1 3.39Å; K232-T235 VanDerWaalsContact O-OG1 3.06Å; K232-I236 WeakPolarHBondContact O-CD1 3.38Å; K232-I236 VanDerWaalsContact O-CG1 3.28Å; K232-I236 WeakPolarHBondContact O-CG1 3.34Å; K232-I236 PolarHBondContact O-N 2.95Å
233	G	87.7	Confident	85.5	Confident	28 Å²	28	88 Å²	88	29%	0.289	42%	0.417	S	S	.	.	H	α-helix	trans	-64.1	-32.9	174.8	0	0	0	0	0	114.6	N231 W237	N231-G233 PolarHBondContact O-N 3.08Å; G233-W237 WeakPolarHBondContact O-CB 3.38Å; G233-W237 PolarHBondContact O-N 2.9Å
234	A	87	Confident	85.5	Confident	2 Å²	2	90.6 Å²	90.6	2%	0.017	43%	0.427	C	S	.	.	H	α-helix	trans	-71.6	-41.8	-177.2	0	0	0	0	0	112.4	Y211 C227 E228 N231 K232 W237 Q238	Y211-A234 HydrophobicContact CD1-CB 4.15Å; C227-A234 HydrophobicContact CB-CB 4.22Å; E228-A234 WeakPolarHBondContact O-CB 3.18Å; N231-A234 HydrophobicContact CB-CB 4.49Å; N231-A234 WeakPolarHBondContact O-CB 3.39Å; N231-A234 PolarHBondContact O-N 3.43Å; K232-A234 PolarHBondContact O-N 3.06Å; A234-W237 PolarHBondContact O-N 3.08Å; A234-Q238 PolarHBondContact O-N 3.25Å
235	T	88.7	Confident	85.5	Confident	59 Å²	59	89 Å²	89	36%	0.362	42%	0.422	S	S	.	.	H	α-helix	trans	-67.4	-40.9	176.7	54	0	0	0	0	111.3	E229 K232 Q238 S239	E229-T235 HydrophobicContact CG-CG2 4.35Å; K232-T235 PolarHBondContact O-OG1 3.39Å; K232-T235 VanDerWaalsContact O-OG1 3.06Å; T235-Q238 PolarHBondContact O-N 3.3Å; T235-S239 PolarHBondContact O-N 3.46Å; T235-S239 VanDerWaalsContact O-N 3.1Å; T235-S239 PolarHBondContact O-OG 3.45Å
236	I	89.9	Confident	85.4	Confident	108 Å²	108	87.8 Å²	87.8	55%	0.554	42%	0.415	S	S	*	.	H	α-helix	trans	-60.3	-48.8	172.5	-65.7	168.4	0	0	0	109.9	K232 Q238 S239 T240	K232-I236 WeakPolarHBondContact O-CD1 3.38Å; K232-I236 VanDerWaalsContact O-CG1 3.28Å; K232-I236 WeakPolarHBondContact O-CG1 3.34Å; K232-I236 PolarHBondContact O-N 2.95Å; I236-Q238 PolarHBondContact O-N 2.85Å; I236-S239 PolarHBondContact O-N 3.36Å; I236-T240 WeakPolarHBondContact O-CB 3.46Å; I236-T240 PolarHBondContact O-N 2.94Å; I236-T240 PolarHBondContact O-OG1 3.45Å
237	W	91.2	Very high	85.6	Confident	39 Å²	39	88.7 Å²	88.7	15%	0.148	42%	0.419	C	S	.	.	H	α-helix	trans	-57.3	-46.7	178.6	174.5	-111.5	0	0	0	112.6	I204 V207 D208 Y211 G233 A234 S239 T240 R241	I204-W237 HydrophobicContact CB-CH2 4.3Å; I204-W237 HydrophobicContact CG2-CH2 3.62Å; I204-W237 HydrophobicContact CG2-CZ2 3.98Å; I204-W237 WeakPolarHBondContact O-CZ2 3.34Å; V207-W237 HydrophobicContact CB-CH2 3.9Å; V207-W237 HydrophobicContact CB-CZ2 4.15Å; V207-W237 HydrophobicContact CB-CZ3 4.22Å; V207-W237 HydrophobicContact CG1-CD2 3.72Å; V207-W237 HydrophobicContact CG1-CE3 3.53Å; V207-W237 HydrophobicContact CG1-CG 4.49Å; V207-W237 HydrophobicContact CG1-CH2 3.58Å; V207-W237 HydrophobicContact CG1-CZ2 3.84Å; V207-W237 HydrophobicContact CG1-CZ3 3.46Å; V207-W237 VanDerWaalsContact CG1-CZ3 3.46Å; D208-W237 HydrophobicContact CB-CZ2 3.89Å; D208-W237 PolarHBondContact OD1-NE1 3.22Å; Y211-W237 HydrophobicContact CD2-CB 4.28Å; Y211-W237 HydrophobicContact CD2-CG 4.24Å; Y211-W237 HydrophobicContact CG-CB 4.43Å; G233-W237 WeakPolarHBondContact O-CB 3.38Å; G233-W237 PolarHBondContact O-N 2.9Å; A234-W237 PolarHBondContact O-N 3.08Å; W237-S239 VanDerWaalsContact C-N 3.34Å; W237-S239 PolarHBondContact O-N 3.45Å; W237-T240 PolarHBondContact O-N 2.79Å; W237-R241 WeakPolarHBondContact O-CB 3.47Å; W237-R241 PolarHBondContact O-N 3.39Å
238	Q	89.2	Confident	85.8	Confident	110 Å²	110	88.1 Å²	88.1	51%	0.514	41%	0.414	S	S	.	.	H	α-helix	trans	-62.2	-43.2	-179.5	-172.9	177.9	7.2	0	0	111.5	A234 T235 I236 F242	A234-Q238 PolarHBondContact O-N 3.25Å; T235-Q238 PolarHBondContact O-N 3.3Å; I236-Q238 PolarHBondContact O-N 2.85Å; Q238-F242 VanDerWaalsContact O-CB 3.3Å; Q238-F242 WeakPolarHBondContact O-CB 3.28Å; Q238-F242 PolarHBondContact O-N 3.31Å
239	S	90.2	Very high	86.3	Confident	62 Å²	62	81.6 Å²	81.6	43%	0.434	38%	0.384	S	S	.	.	H	α-helix	trans	-63	-51.2	175.3	-67.9	0	0	0	0	111.2	T235 I236 W237 R241 F242 Y243	T235-S239 PolarHBondContact O-N 3.46Å; T235-S239 VanDerWaalsContact O-N 3.1Å; T235-S239 PolarHBondContact O-OG 3.45Å; I236-S239 PolarHBondContact O-N 3.36Å; W237-S239 VanDerWaalsContact C-N 3.34Å; W237-S239 PolarHBondContact O-N 3.45Å; S239-R241 VanDerWaalsContact C-N 3.35Å; S239-R241 PolarHBondContact O-N 2.64Å; S239-F242 WeakPolarHBondContact O-CB 3.43Å; S239-F242 PolarHBondContact O-N 3.21Å; S239-Y243 WeakPolarHBondContact O-CD2 3.46Å; S239-Y243 PolarHBondContact O-N 3.24Å
240	T	91.2	Very high	87.1	Confident	75 Å²	75	77.5 Å²	77.5	46%	0.46	37%	0.367	S	S	.	.	H	α-helix	trans	-57.1	-47.9	177.9	-61.4	0	0	0	0	111.4	I236 W237 F242 Y243 W244	I236-T240 WeakPolarHBondContact O-CB 3.46Å; I236-T240 PolarHBondContact O-N 2.94Å; I236-T240 PolarHBondContact O-OG1 3.45Å; W237-T240 PolarHBondContact O-N 2.79Å; T240-F242 VanDerWaalsContact C-N 3.33Å; T240-F242 PolarHBondContact O-N 2.87Å; T240-Y243 PolarHBondContact O-N 3.24Å; T240-W244 WeakPolarHBondContact O-CB 3.35Å; T240-W244 PolarHBondContact O-N 3.1Å
241	R	90	Very high	88.4	Confident	48 Å²	48	68.5 Å²	68.5	18%	0.181	34%	0.336	C	S	.	.	H	α-helix	trans	-60.6	-44	178	179.3	175.6	165.4	-145.1	-16.1	111.2	D208 W237 S239 W244 T245	D208-R241 WeakPolarHBondContact OD1-CD 3.28Å; D208-R241 IonicContact OD1-CZ 3.46Å; D208-R241 IonicContact OD1-NE 3.04Å; D208-R241 IonicContact OD1-NH1 2.64Å; D208-R241 PolarHBondContact OD1-NH1 2.93Å; D208-R241 IonicContact OD2-NH1 3.54Å; D208-R241 PolarHBondContact OD2-NH1 3.01Å; W237-R241 WeakPolarHBondContact O-CB 3.47Å; W237-R241 PolarHBondContact O-N 3.39Å; S239-R241 VanDerWaalsContact C-N 3.35Å; S239-R241 PolarHBondContact O-N 2.64Å; R241-W244 PolarHBondContact O-N 3.29Å; R241-T245 HydrophobicContact CG-CG2 4.37Å; R241-T245 VanDerWaalsContact O-CG2 3.23Å; R241-T245 WeakPolarHBondContact O-CG2 3.35Å; R241-T245 PolarHBondContact O-N 3.42Å; R241-T245 PolarHBondContact O-OG1 3.42Å; R241-T245 VanDerWaalsContact O-OG1 3.08Å
242	F	87.7	Confident	89.2	Confident	47 Å²	47	64.2 Å²	64.2	21%	0.206	31%	0.313	C	S	.	.	H	α-helix	trans	-60.3	-51.8	178.2	175.4	-109.2	0	0	0	111.9	Q238 S239 T240 W244 T245 M246 K365	Q238-F242 VanDerWaalsContact O-CB 3.3Å; Q238-F242 WeakPolarHBondContact O-CB 3.28Å; Q238-F242 PolarHBondContact O-N 3.31Å; S239-F242 WeakPolarHBondContact O-CB 3.43Å; S239-F242 PolarHBondContact O-N 3.21Å; T240-F242 VanDerWaalsContact C-N 3.33Å; T240-F242 PolarHBondContact O-N 2.87Å; F242-W244 VanDerWaalsContact C-N 3.3Å; F242-W244 PolarHBondContact O-N 2.91Å; F242-T245 PolarHBondContact O-N 3.16Å; F242-T245 PolarHBondContact O-OG1 2.93Å; F242-M246 HydrophobicContact CE1-CE 4.32Å; F242-M246 HydrophobicContact CE1-SD 3.77Å; F242-M246 HydrophobicContact CE2-CE 3.49Å; F242-M246 VanDerWaalsContact CE2-CE 3.49Å; F242-M246 HydrophobicContact CE2-CG 4.18Å; F242-M246 HydrophobicContact CE2-SD 3.76Å; F242-M246 HydrophobicContact CZ-CE 3.24Å; F242-M246 HydrophobicContact CZ-CG 4.2Å; F242-M246 HydrophobicContact CZ-SD 3.22Å; F242-M246 WeakPolarHBondContact CZ-SD 3.22Å; F242-M246 PolarHBondContact O-N 3.09Å; F242-K365 HydrophobicContact CD2-CD 4.25Å; F242-K365 VanDerWaalsContact CD2-CE 3.4Å; F242-K365 HydrophobicContact CE2-CD 3.4Å; F242-K365 VanDerWaalsContact CE2-CD 3.4Å; F242-K365 HydrophobicContact CZ-CD 3.64Å
243	Y	89.8	Confident	89.4	Confident	161 Å²	161	58 Å²	58	63%	0.631	29%	0.286	S	S	*	.	H	α-helix	trans	-59.3	-43	177	-71.3	-61.5	0	0	0	111.7	S239 T240 T245 M246 F247	S239-Y243 WeakPolarHBondContact O-CD2 3.46Å; S239-Y243 PolarHBondContact O-N 3.24Å; T240-Y243 PolarHBondContact O-N 3.24Å; Y243-T245 VanDerWaalsContact C-N 3.34Å; Y243-T245 PolarHBondContact O-N 3.3Å; Y243-M246 PolarHBondContact O-N 3.43Å; Y243-F247 WeakPolarHBondContact O-CB 3.35Å; Y243-F247 PolarHBondContact O-N 2.66Å
244	W	89.2	Confident	89.5	Confident	106 Å²	106	60.8 Å²	60.8	40%	0.402	30%	0.298	S	S	.	.	H	α-helix	trans	-61.3	-41.3	178.6	-172.6	-107.8	0	0	0	112.9	Y163 T240 R241 F242 M246 F247 L248	Y163-W244 HydrophobicContact CE1-CZ2 4.27Å; Y163-W244 AromaticContact CE1-NE1 3.23Å; Y163-W244 AromaticContact CZ-CE2 4Å; Y163-W244 AromaticContact CZ-CZ2 3.94Å; Y163-W244 AromaticContact CZ-NE1 3.42Å; Y163-W244 VanDerWaalsContact OH-CE2 3.23Å; Y163-W244 VanDerWaalsContact OH-CZ2 3.27Å; Y163-W244 WeakPolarHBondContact OH-CZ2 3.33Å; Y163-W244 PolarHBondContact OH-NE1 2.98Å; T240-W244 WeakPolarHBondContact O-CB 3.35Å; T240-W244 PolarHBondContact O-N 3.1Å; R241-W244 PolarHBondContact O-N 3.29Å; F242-W244 VanDerWaalsContact C-N 3.3Å; F242-W244 PolarHBondContact O-N 2.91Å; W244-M246 VanDerWaalsContact C-N 3.29Å; W244-M246 PolarHBondContact O-N 3.3Å; W244-F247 PolarHBondContact O-N 3.05Å; W244-L248 HydrophobicContact CD2-CD1 4.32Å; W244-L248 HydrophobicContact CD2-CG 4.47Å; W244-L248 HydrophobicContact CZ2-CD1 3.77Å; W244-L248 HydrophobicContact CZ2-CD2 4.28Å; W244-L248 HydrophobicContact CZ2-CG 4.15Å; W244-L248 PolarHBondContact O-N 3.43Å
245	T	88.8	Confident	89.7	Confident	20 Å²	20	61.6 Å²	61.6	12%	0.123	30%	0.302	C	S	.	.	H	α-helix	trans	-71	-21.6	178.8	55.1	0	0	0	0	114.1	Y158 L162 R241 F242 Y243 P249	Y158-T245 HydrophobicContact CE1-CG2 3.68Å; L162-T245 HydrophobicContact CD2-CG2 4.4Å; R241-T245 HydrophobicContact CG-CG2 4.37Å; R241-T245 VanDerWaalsContact O-CG2 3.23Å; R241-T245 WeakPolarHBondContact O-CG2 3.35Å; R241-T245 PolarHBondContact O-N 3.42Å; R241-T245 PolarHBondContact O-OG1 3.42Å; R241-T245 VanDerWaalsContact O-OG1 3.08Å; F242-T245 PolarHBondContact O-N 3.16Å; F242-T245 PolarHBondContact O-OG1 2.93Å; Y243-T245 VanDerWaalsContact C-N 3.34Å; Y243-T245 PolarHBondContact O-N 3.3Å; T245-P249 WeakPolarHBondContact O-CD 3.4Å; T245-P249 VanDerWaalsContact O-CG 3.31Å; T245-P249 WeakPolarHBondContact O-CG 3.4Å
246	M	86.4	Confident	89.7	Confident	53 Å²	53	59.5 Å²	59.5	26%	0.261	29%	0.287	S	S	.	.	H	α-helix	trans	-87.5	-41.2	171.9	-74.8	-168.7	155.7	0	0	112	F242 Y243 W244 L248 P249 D250 A361	F242-M246 HydrophobicContact CE1-CE 4.32Å; F242-M246 HydrophobicContact CE1-SD 3.77Å; F242-M246 HydrophobicContact CE2-CE 3.49Å; F242-M246 VanDerWaalsContact CE2-CE 3.49Å; F242-M246 HydrophobicContact CE2-CG 4.18Å; F242-M246 HydrophobicContact CE2-SD 3.76Å; F242-M246 HydrophobicContact CZ-CE 3.24Å; F242-M246 HydrophobicContact CZ-CG 4.2Å; F242-M246 HydrophobicContact CZ-SD 3.22Å; F242-M246 WeakPolarHBondContact CZ-SD 3.22Å; F242-M246 PolarHBondContact O-N 3.09Å; Y243-M246 PolarHBondContact O-N 3.43Å; W244-M246 VanDerWaalsContact C-N 3.29Å; W244-M246 PolarHBondContact O-N 3.3Å; M246-L248 PolarHBondContact O-N 3.17Å; M246-P249 VanDerWaalsContact O-CD 3.28Å; M246-P249 WeakPolarHBondContact O-CD 3.44Å; M246-D250 PolarHBondContact O-N 2.96Å; M246-D250 VanDerWaalsContact O-OD2 3.12Å; M246-A361 HydrophobicContact CE-CB 4.05Å
247	F	90.4	Very high	89.6	Confident	113 Å²	113	56.2 Å²	56.2	50%	0.496	27%	0.272	S	S	.	.	H	α-helix	trans	-66.3	-38.9	-174.6	-178	-114	0	0	0	113.3	Y243 W244 D250 I251	Y243-F247 WeakPolarHBondContact O-CB 3.35Å; Y243-F247 PolarHBondContact O-N 2.66Å; W244-F247 PolarHBondContact O-N 3.05Å; F247-D250 PolarHBondContact O-N 3.31Å; F247-I251 HydrophobicContact CD1-CD1 3.56Å; F247-I251 HydrophobicContact CD1-CG1 4.42Å; F247-I251 HydrophobicContact CD2-CD1 4.45Å; F247-I251 HydrophobicContact CE1-CD1 3.12Å; F247-I251 HydrophobicContact CE1-CG1 4.09Å; F247-I251 HydrophobicContact CE2-CD1 4.08Å; F247-I251 HydrophobicContact CE2-CG1 4.17Å; F247-I251 HydrophobicContact CG-CD1 4.21Å; F247-I251 HydrophobicContact CZ-CD1 3.41Å; F247-I251 VanDerWaalsContact CZ-CD1 3.41Å; F247-I251 HydrophobicContact CZ-CG1 3.94Å; F247-I251 WeakPolarHBondContact O-CG1 3.49Å; F247-I251 PolarHBondContact O-N 3.11Å
248	L	91.4	Very high	89.6	Confident	8 Å²	8	57 Å²	57	4%	0.042	28%	0.281	C	S	.	.	H	α-helix	trans	-65.5	-48.4	-179.2	-81.6	177.4	0	0	0	113.4	L162 Y163 F166 W244 M246 D250 I251 M252	L162-L248 HydrophobicContact CD1-CB 3.88Å; L162-L248 HydrophobicContact CD2-CB 4.06Å; L162-L248 HydrophobicContact CD2-CD1 3.65Å; L162-L248 HydrophobicContact CD2-CG 4.48Å; L162-L248 HydrophobicContact CG-CB 4.04Å; L162-L248 HydrophobicContact CG-CD1 3.77Å; Y163-L248 HydrophobicContact CD1-CD1 3.93Å; Y163-L248 HydrophobicContact CE1-CD1 3.64Å; F166-L248 HydrophobicContact CD2-CD2 4.14Å; F166-L248 HydrophobicContact CG-CD2 4.19Å; W244-L248 HydrophobicContact CD2-CD1 4.32Å; W244-L248 HydrophobicContact CD2-CG 4.47Å; W244-L248 HydrophobicContact CZ2-CD1 3.77Å; W244-L248 HydrophobicContact CZ2-CD2 4.28Å; W244-L248 HydrophobicContact CZ2-CG 4.15Å; W244-L248 PolarHBondContact O-N 3.43Å; M246-L248 PolarHBondContact O-N 3.17Å; L248-D250 VanDerWaalsContact C-N 3.31Å; L248-D250 PolarHBondContact O-N 3.44Å; L248-I251 PolarHBondContact O-N 2.92Å; L248-M252 WeakPolarHBondContact O-CG 3.44Å; L248-M252 PolarHBondContact O-N 2.93Å
249	P	89.5	Confident	89.5	Confident	1 Å²	1	51.8 Å²	51.8	1%	0.006	26%	0.257	C	S	.	.	H	α-helix	trans	-57.1	-41.8	171.9	-27.2	36.7	0	0	0	113.1	L162 T245 M246 I251 M252 F253 L357 E358	L162-P249 HydrophobicContact CD1-CG 3.79Å; T245-P249 WeakPolarHBondContact O-CD 3.4Å; T245-P249 VanDerWaalsContact O-CG 3.31Å; T245-P249 WeakPolarHBondContact O-CG 3.4Å; M246-P249 VanDerWaalsContact O-CD 3.28Å; M246-P249 WeakPolarHBondContact O-CD 3.44Å; P249-I251 PolarHBondContact O-N 2.84Å; P249-M252 WeakPolarHBondContact O-CB 3.1Å; P249-M252 PolarHBondContact O-N 3.28Å; P249-M252 VanDerWaalsContact O-N 3.11Å; P249-F253 WeakPolarHBondContact O-CB 3.27Å; P249-F253 PolarHBondContact O-N 2.9Å; P249-L357 HydrophobicContact CG-CB 4.17Å; P249-E358 HydrophobicContact CB-CG 3.78Å
250	D	87.6	Confident	89.4	Confident	78 Å²	78	50.1 Å²	50.1	42%	0.417	24%	0.242	S	C	.	.	H	α-helix	trans	-59.8	-44.4	177.8	-66.5	-27	0	0	0	111.7	M246 F247 L248 F253 V254	M246-D250 PolarHBondContact O-N 2.96Å; M246-D250 VanDerWaalsContact O-OD2 3.12Å; F247-D250 PolarHBondContact O-N 3.31Å; L248-D250 VanDerWaalsContact C-N 3.31Å; L248-D250 PolarHBondContact O-N 3.44Å; D250-F253 WeakPolarHBondContact O-CB 3.4Å; D250-F253 PolarHBondContact O-N 2.82Å; D250-V254 WeakPolarHBondContact O-CG2 3.3Å; D250-V254 PolarHBondContact O-N 3.46Å
251	I	91.7	Very high	89.2	Confident	48 Å²	48	52.9 Å²	52.9	25%	0.246	25%	0.245	C	C	.	.	H	α-helix	trans	-61.2	-46.8	174.3	-67.8	164.8	0	0	0	110.6	F166 F247 L248 P249 F253 V254 M255	F166-I251 HydrophobicContact CE2-CG2 3.82Å; F247-I251 HydrophobicContact CD1-CD1 3.56Å; F247-I251 HydrophobicContact CD1-CG1 4.42Å; F247-I251 HydrophobicContact CD2-CD1 4.45Å; F247-I251 HydrophobicContact CE1-CD1 3.12Å; F247-I251 HydrophobicContact CE1-CG1 4.09Å; F247-I251 HydrophobicContact CE2-CD1 4.08Å; F247-I251 HydrophobicContact CE2-CG1 4.17Å; F247-I251 HydrophobicContact CG-CD1 4.21Å; F247-I251 HydrophobicContact CZ-CD1 3.41Å; F247-I251 VanDerWaalsContact CZ-CD1 3.41Å; F247-I251 HydrophobicContact CZ-CG1 3.94Å; F247-I251 WeakPolarHBondContact O-CG1 3.49Å; F247-I251 PolarHBondContact O-N 3.11Å; L248-I251 PolarHBondContact O-N 2.92Å; P249-I251 PolarHBondContact O-N 2.84Å; I251-F253 VanDerWaalsContact C-N 3.25Å; I251-F253 PolarHBondContact O-N 3.34Å; I251-V254 PolarHBondContact O-N 3.23Å; I251-M255 HydrophobicContact CG2-CG 4.2Å; I251-M255 HydrophobicContact CG2-SD 3.74Å; I251-M255 VanDerWaalsContact O-CG 3.27Å; I251-M255 WeakPolarHBondContact O-CG 3.4Å; I251-M255 PolarHBondContact O-N 3.49Å
252	M	91.8	Very high	89.1	Confident	2 Å²	2	51.4 Å²	51.4	1%	0.01	24%	0.242	C	C	.	.	H	α-helix	trans	-58.9	-42	179.8	-69.3	170.1	56.2	0	0	111	S165 F166 T169 L248 P249 M255 Y256	S165-M252 VanDerWaalsContact CB-CE 3.47Å; F166-M252 HydrophobicContact CB-CG 4.17Å; F166-M252 HydrophobicContact CB-SD 3.93Å; F166-M252 HydrophobicContact CD2-CG 3.8Å; F166-M252 HydrophobicContact CG-CG 4.49Å; T169-M252 HydrophobicContact CG2-CB 4.22Å; T169-M252 HydrophobicContact CG2-CG 4.37Å; T169-M252 WeakPolarHBondContact OG1-CE 3.44Å; L248-M252 WeakPolarHBondContact O-CG 3.44Å; L248-M252 PolarHBondContact O-N 2.93Å; P249-M252 WeakPolarHBondContact O-CB 3.1Å; P249-M252 PolarHBondContact O-N 3.28Å; P249-M252 VanDerWaalsContact O-N 3.11Å; M252-M255 WeakPolarHBondContact O-CB 3.26Å; M252-M255 PolarHBondContact O-N 3.34Å; M252-Y256 HydrophobicContact CB-CE2 4.44Å; M252-Y256 WeakPolarHBondContact O-CD2 3.36Å; M252-Y256 PolarHBondContact O-N 3.06Å
253	F	88	Confident	88.9	Confident	49 Å²	49	49.6 Å²	49.6	22%	0.215	23%	0.234	C	C	.	.	H	α-helix	trans	-59.6	-50.6	176.4	178.1	-106.7	0	0	0	111.6	P249 D250 I251 M255 Y256 V257 F312	P249-F253 WeakPolarHBondContact O-CB 3.27Å; P249-F253 PolarHBondContact O-N 2.9Å; D250-F253 WeakPolarHBondContact O-CB 3.4Å; D250-F253 PolarHBondContact O-N 2.82Å; I251-F253 VanDerWaalsContact C-N 3.25Å; I251-F253 PolarHBondContact O-N 3.34Å; F253-M255 VanDerWaalsContact C-N 3.29Å; F253-M255 PolarHBondContact O-N 2.9Å; F253-Y256 PolarHBondContact O-N 2.86Å; F253-V257 HydrophobicContact CD1-CG2 4.44Å; F253-V257 HydrophobicContact CE1-CG2 4.03Å; F253-V257 HydrophobicContact CE2-CG2 4.32Å; F253-V257 HydrophobicContact CZ-CG2 3.97Å; F253-V257 WeakPolarHBondContact O-CG2 3.17Å; F253-V257 PolarHBondContact O-N 3.46Å; F253-F312 AromaticContact CD2-CE2 3.45Å; F253-F312 HydrophobicContact CD2-CE2 3.45Å; F253-F312 VanDerWaalsContact CD2-CE2 3.45Å; F253-F312 AromaticContact CD2-CZ 3.92Å; F253-F312 HydrophobicContact CD2-CZ 3.92Å; F253-F312 HydrophobicContact CE2-CD2 4.03Å; F253-F312 AromaticContact CE2-CE2 3.22Å; F253-F312 HydrophobicContact CE2-CE2 3.22Å; F253-F312 AromaticContact CE2-CZ 3.82Å; F253-F312 HydrophobicContact CE2-CZ 3.82Å; F253-F312 HydrophobicContact CG-CE2 4.32Å; F253-F312 HydrophobicContact CZ-CD2 4.35Å; F253-F312 AromaticContact CZ-CE2 3.93Å; F253-F312 HydrophobicContact CZ-CE2 3.93Å
254	V	89.5	Confident	88.6	Confident	88 Å²	88	43.8 Å²	43.8	53%	0.533	21%	0.211	S	C	.	.	H	α-helix	trans	-57.6	-43.2	176.3	172.9	0	0	0	0	111.2	D250 I251 Y256 V257 V258	D250-V254 WeakPolarHBondContact O-CG2 3.3Å; D250-V254 PolarHBondContact O-N 3.46Å; I251-V254 PolarHBondContact O-N 3.23Å; V254-Y256 VanDerWaalsContact C-N 3.32Å; V254-Y256 PolarHBondContact O-N 2.83Å; V254-V257 PolarHBondContact O-N 3.46Å; V254-V258 WeakPolarHBondContact O-CG2 3.34Å; V254-V258 PolarHBondContact O-N 3.37Å
255	M	92.3	Very high	88.5	Confident	19 Å²	19	46.3 Å²	46.3	9%	0.094	22%	0.22	C	C	.	.	H	α-helix	trans	-60.6	-40.6	176.2	-68.9	172.1	76.5	0	0	111.9	F166 T169 L170 F173 I251 M252 F253 V258 I259	F166-M255 HydrophobicContact CE2-SD 3.95Å; T169-M255 HydrophobicContact CG2-CB 3.7Å; T169-M255 HydrophobicContact CG2-CE 4.1Å; T169-M255 HydrophobicContact CG2-CG 4.48Å; T169-M255 HydrophobicContact CG2-SD 4.01Å; L170-M255 HydrophobicContact CB-CE 4.12Å; L170-M255 HydrophobicContact CD1-CE 3.74Å; F173-M255 HydrophobicContact CB-CE 3.38Å; F173-M255 HydrophobicContact CD1-CE 4.14Å; F173-M255 HydrophobicContact CD2-CB 3.93Å; F173-M255 HydrophobicContact CD2-CE 4.01Å; F173-M255 HydrophobicContact CD2-CG 4.08Å; F173-M255 HydrophobicContact CE2-CG 4.42Å; F173-M255 HydrophobicContact CG-CE 3.59Å; I251-M255 HydrophobicContact CG2-CG 4.2Å; I251-M255 HydrophobicContact CG2-SD 3.74Å; I251-M255 VanDerWaalsContact O-CG 3.27Å; I251-M255 WeakPolarHBondContact O-CG 3.4Å; I251-M255 PolarHBondContact O-N 3.49Å; M252-M255 WeakPolarHBondContact O-CB 3.26Å; M252-M255 PolarHBondContact O-N 3.34Å; F253-M255 VanDerWaalsContact C-N 3.29Å; F253-M255 PolarHBondContact O-N 2.9Å; M255-V258 PolarHBondContact O-N 2.81Å; M255-I259 VanDerWaalsContact O-CG1 3.23Å; M255-I259 WeakPolarHBondContact O-CG1 3.43Å; M255-I259 PolarHBondContact O-N 2.74Å
256	Y	88.4	Confident	88.2	Confident	15 Å²	15	50.3 Å²	50.3	6%	0.059	24%	0.236	C	C	.	.	H	α-helix	trans	-66.9	-38.9	176.2	-77.9	-57.6	0	0	0	113.1	T169 M252 F253 V254 V258 I259 F260 L347 A350	T169-Y256 WeakPolarHBondContact CA-OH 3.34Å; T169-Y256 WeakPolarHBondContact CB-OH 3.43Å; T169-Y256 HydrophobicContact CG2-CD2 4.02Å; T169-Y256 HydrophobicContact CG2-CE1 4.12Å; T169-Y256 HydrophobicContact CG2-CE2 3.47Å; T169-Y256 VanDerWaalsContact CG2-CE2 3.47Å; T169-Y256 VanDerWaalsContact CG2-CZ 3.49Å; T169-Y256 WeakPolarHBondContact OG1-CE2 3.48Å; T169-Y256 PolarHBondContact OG1-OH 2.94Å; M252-Y256 HydrophobicContact CB-CE2 4.44Å; M252-Y256 WeakPolarHBondContact O-CD2 3.36Å; M252-Y256 PolarHBondContact O-N 3.06Å; F253-Y256 PolarHBondContact O-N 2.86Å; V254-Y256 VanDerWaalsContact C-N 3.32Å; V254-Y256 PolarHBondContact O-N 2.83Å; Y256-V258 VanDerWaalsContact C-N 3.31Å; Y256-V258 PolarHBondContact O-N 2.88Å; Y256-I259 HydrophobicContact CD1-CD1 4.07Å; Y256-I259 HydrophobicContact CE1-CD1 4.24Å; Y256-I259 PolarHBondContact O-N 3.17Å; Y256-F260 VanDerWaalsContact O-CB 3.24Å; Y256-F260 WeakPolarHBondContact O-CB 3.5Å; Y256-F260 PolarHBondContact O-N 3.27Å; Y256-L347 HydrophobicContact CD1-CD2 3.71Å; Y256-L347 HydrophobicContact CE1-CD2 4.21Å; Y256-A350 HydrophobicContact CD1-CB 3.83Å; Y256-A350 HydrophobicContact CD2-CB 4.04Å; Y256-A350 HydrophobicContact CE1-CB 3.18Å; Y256-A350 HydrophobicContact CE2-CB 3.43Å; Y256-A350 VanDerWaalsContact CE2-CB 3.43Å; Y256-A350 HydrophobicContact CG-CB 4.25Å; Y256-A350 WeakPolarHBondContact OH-CB 3.34Å
257	V	86.7	Confident	87.9	Confident	39 Å²	39	50 Å²	50	24%	0.236	23%	0.234	C	C	.	.	H	α-helix	trans	-58.4	-45.2	172.5	173.5	0	0	0	0	110.5	F253 V254 F260 Y261 F287	F253-V257 HydrophobicContact CD1-CG2 4.44Å; F253-V257 HydrophobicContact CE1-CG2 4.03Å; F253-V257 HydrophobicContact CE2-CG2 4.32Å; F253-V257 HydrophobicContact CZ-CG2 3.97Å; F253-V257 WeakPolarHBondContact O-CG2 3.17Å; F253-V257 PolarHBondContact O-N 3.46Å; V254-V257 PolarHBondContact O-N 3.46Å; V257-F260 PolarHBondContact O-N 2.94Å; V257-Y261 WeakPolarHBondContact O-CB 3.38Å; V257-Y261 PolarHBondContact O-N 2.79Å; V257-F287 HydrophobicContact CG1-CZ 4.48Å
258	V	91.3	Very high	87.4	Confident	56 Å²	56	49.7 Å²	49.7	34%	0.339	23%	0.229	S	C	.	.	H	α-helix	trans	-64.7	-44.7	177.6	175.5	0	0	0	0	111.9	F173 I177 V254 M255 Y256 F260 Y261 S262	F173-V258 HydrophobicContact CE2-CB 4.04Å; F173-V258 HydrophobicContact CE2-CG1 3.73Å; F173-V258 HydrophobicContact CZ-CG1 4.41Å; I177-V258 HydrophobicContact CD1-CG1 3.87Å; I177-V258 HydrophobicContact CG1-CG1 4.08Å; V254-V258 WeakPolarHBondContact O-CG2 3.34Å; V254-V258 PolarHBondContact O-N 3.37Å; M255-V258 PolarHBondContact O-N 2.81Å; Y256-V258 VanDerWaalsContact C-N 3.31Å; Y256-V258 PolarHBondContact O-N 2.88Å; V258-F260 VanDerWaalsContact C-N 3.34Å; V258-F260 PolarHBondContact O-N 2.84Å; V258-Y261 PolarHBondContact O-N 3.25Å; V258-S262 WeakPolarHBondContact O-CB 3.11Å; V258-S262 PolarHBondContact O-N 3.13Å
259	I	88.3	Confident	86.8	Confident	0 Å²	0	54.4 Å²	54.4	0%	0	25%	0.254	C	S	.	.	H	α-helix	trans	-58.8	-48.8	176.2	-67.6	162.7	0	0	0	109.9	R172 F173 F176 I177 M255 Y256 Y261 S262 I263 L347	R172-I259 HydrophobicContact CB-CD1 4.14Å; F173-I259 HydrophobicContact CB-CD1 4.05Å; F173-I259 HydrophobicContact CB-CG1 4.39Å; F173-I259 HydrophobicContact CD2-CD1 4.39Å; F173-I259 HydrophobicContact CD2-CG1 4.07Å; F176-I259 HydrophobicContact CB-CG2 4.27Å; F176-I259 HydrophobicContact CD2-CG2 3.67Å; F176-I259 HydrophobicContact CE2-CG2 4.35Å; F176-I259 HydrophobicContact CG-CG2 4.04Å; I177-I259 HydrophobicContact CG1-CG1 4.43Å; M255-I259 VanDerWaalsContact O-CG1 3.23Å; M255-I259 WeakPolarHBondContact O-CG1 3.43Å; M255-I259 PolarHBondContact O-N 2.74Å; Y256-I259 HydrophobicContact CD1-CD1 4.07Å; Y256-I259 HydrophobicContact CE1-CD1 4.24Å; Y256-I259 PolarHBondContact O-N 3.17Å; I259-Y261 PolarHBondContact O-N 2.98Å; I259-S262 WeakPolarHBondContact O-CB 3.45Å; I259-S262 PolarHBondContact O-N 2.72Å; I259-S262 VanDerWaalsContact O-N 3.15Å; I259-S262 PolarHBondContact O-OG 3.3Å; I259-I263 HydrophobicContact CG2-CD1 3.71Å; I259-I263 HydrophobicContact CG2-CG1 4.47Å; I259-I263 WeakPolarHBondContact O-CG1 2.8Å; I259-I263 PolarHBondContact O-N 2.75Å; I259-L347 HydrophobicContact CB-CD2 4.4Å; I259-L347 HydrophobicContact CG2-CD2 3.79Å
260	F	86.6	Confident	86.2	Confident	27 Å²	27	55.7 Å²	55.7	12%	0.118	27%	0.265	C	S	.	.	H	α-helix	trans	-57.9	-48.9	178.9	-179.3	-94	0	0	0	112.1	Y256 V257 V258 S262 I263 R264 F287 L319 W344 L347	Y256-F260 VanDerWaalsContact O-CB 3.24Å; Y256-F260 WeakPolarHBondContact O-CB 3.5Å; Y256-F260 PolarHBondContact O-N 3.27Å; V257-F260 PolarHBondContact O-N 2.94Å; V258-F260 VanDerWaalsContact C-N 3.34Å; V258-F260 PolarHBondContact O-N 2.84Å; F260-S262 VanDerWaalsContact C-N 3.28Å; F260-S262 PolarHBondContact O-N 2.96Å; F260-I263 PolarHBondContact O-N 2.89Å; F260-R264 WeakPolarHBondContact O-CB 3.42Å; F260-R264 PolarHBondContact O-N 3.13Å; F260-F287 HydrophobicContact CD1-CD2 4.38Å; F260-F287 HydrophobicContact CD1-CE1 4.29Å; F260-F287 AromaticContact CD1-CE2 3.69Å; F260-F287 HydrophobicContact CD1-CE2 3.69Å; F260-F287 AromaticContact CD1-CZ 3.63Å; F260-F287 HydrophobicContact CD1-CZ 3.63Å; F260-F287 HydrophobicContact CE1-CD1 4.49Å; F260-F287 AromaticContact CE1-CD2 3.73Å; F260-F287 HydrophobicContact CE1-CD2 3.73Å; F260-F287 HydrophobicContact CE1-CE1 4.29Å; F260-F287 AromaticContact CE1-CE2 3.49Å; F260-F287 HydrophobicContact CE1-CE2 3.49Å; F260-F287 VanDerWaalsContact CE1-CE2 3.49Å; F260-F287 HydrophobicContact CE1-CG 4.23Å; F260-F287 AromaticContact CE1-CZ 3.8Å; F260-F287 HydrophobicContact CE1-CZ 3.8Å; F260-F287 HydrophobicContact CZ-CD2 4.23Å; F260-F287 HydrophobicContact CZ-CE2 4.16Å; F260-L319 HydrophobicContact CE2-CD2 4.12Å; F260-L319 HydrophobicContact CZ-CD2 4.07Å; F260-W344 HydrophobicContact CD2-CH2 4.28Å; F260-W344 HydrophobicContact CD2-CZ3 4.43Å; F260-W344 AromaticContact CE2-CH2 3.35Å; F260-W344 HydrophobicContact CE2-CH2 3.35Å; F260-W344 HydrophobicContact CE2-CZ2 4.13Å; F260-W344 AromaticContact CE2-CZ3 3.77Å; F260-W344 HydrophobicContact CE2-CZ3 3.77Å; F260-W344 HydrophobicContact CZ-CH2 4.1Å; F260-L347 HydrophobicContact CD2-CD1 4.48Å
261	Y	87.3	Confident	85.5	Confident	133 Å²	133	54.5 Å²	54.5	52%	0.522	27%	0.266	S	S	.	.	H	α-helix	trans	-58.5	-42.2	176.4	-179.8	-94	0	0	0	111.5	V257 V258 I259 R264 R265	V257-Y261 WeakPolarHBondContact O-CB 3.38Å; V257-Y261 PolarHBondContact O-N 2.79Å; V258-Y261 PolarHBondContact O-N 3.25Å; I259-Y261 PolarHBondContact O-N 2.98Å; Y261-R264 PolarHBondContact O-N 2.93Å; Y261-R265 WeakPolarHBondContact O-CB 3.33Å; Y261-R265 PolarHBondContact O-N 2.92Å
262	S	88	Confident	84.5	Confident	17 Å²	17	57.2 Å²	57.2	12%	0.119	28%	0.281	C	S	.	.	H	α-helix	trans	-64.4	-41.7	179.4	81.4	0	0	0	0	113	I177 V258 I259 F260 R265 K266	I177-S262 WeakPolarHBondContact CD1-OG 3.14Å; V258-S262 WeakPolarHBondContact O-CB 3.11Å; V258-S262 PolarHBondContact O-N 3.13Å; I259-S262 WeakPolarHBondContact O-CB 3.45Å; I259-S262 PolarHBondContact O-N 2.72Å; I259-S262 VanDerWaalsContact O-N 3.15Å; I259-S262 PolarHBondContact O-OG 3.3Å; F260-S262 VanDerWaalsContact C-N 3.28Å; F260-S262 PolarHBondContact O-N 2.96Å; S262-R265 PolarHBondContact O-N 3.47Å; S262-K266 WeakPolarHBondContact O-CG 3.34Å; S262-K266 PolarHBondContact O-N 2.95Å
263	I	84.9	Confident	83.3	Confident	8 Å²	8	62.7 Å²	62.7	4%	0.041	31%	0.314	C	S	.	.	H	α-helix	trans	-64.9	-47.6	177.2	-69.8	164	0	0	0	109.2	F176 I259 F260 R265 K266 Q267 L347	F176-I263 HydrophobicContact CD1-CD1 4.37Å; F176-I263 HydrophobicContact CD1-CG1 4.21Å; F176-I263 HydrophobicContact CE1-CD1 4.35Å; F176-I263 HydrophobicContact CE1-CG1 4.46Å; I259-I263 HydrophobicContact CG2-CD1 3.71Å; I259-I263 HydrophobicContact CG2-CG1 4.47Å; I259-I263 WeakPolarHBondContact O-CG1 2.8Å; I259-I263 PolarHBondContact O-N 2.75Å; F260-I263 PolarHBondContact O-N 2.89Å; I263-R265 VanDerWaalsContact C-N 3.31Å; I263-R265 PolarHBondContact O-N 3.35Å; I263-K266 PolarHBondContact O-N 3.35Å; I263-K266 VanDerWaalsContact O-N 3.16Å; I263-Q267 WeakPolarHBondContact O-CG 3.32Å; I263-Q267 PolarHBondContact O-N 3.42Å; I263-L347 HydrophobicContact CD1-CD1 3.77Å
264	R	83.5	Confident	82.1	Confident	40 Å²	40	65 Å²	65	15%	0.151	33%	0.328	C	S	.	.	H	α-helix	trans	-61.8	-38.4	178.3	-167.4	173.7	-172.3	172.4	2.5	112.5	F260 Y261 Q267 R268 F283	F260-R264 WeakPolarHBondContact O-CB 3.42Å; F260-R264 PolarHBondContact O-N 3.13Å; Y261-R264 PolarHBondContact O-N 2.93Å; R264-Q267 PolarHBondContact O-N 3.44Å; R264-R268 WeakPolarHBondContact O-CG 3.39Å; R264-R268 PolarHBondContact O-N 3.28Å; R264-F283 VanDerWaalsContact NH2-C 3.33Å; R264-F283 PolarHBondContact NH2-O 2.9Å
265	R	85.4	Confident	80.3	Confident	158 Å²	158	68.1 Å²	68.1	60%	0.596	34%	0.338	S	S	*	.	H	α-helix	trans	-63.3	-45.7	174.9	-176.5	179.2	176.6	-172.7	0.2	111.2	Y261 S262 I263 Q267 R268 L269	Y261-R265 WeakPolarHBondContact O-CB 3.33Å; Y261-R265 PolarHBondContact O-N 2.92Å; S262-R265 PolarHBondContact O-N 3.47Å; I263-R265 VanDerWaalsContact C-N 3.31Å; I263-R265 PolarHBondContact O-N 3.35Å; R265-Q267 VanDerWaalsContact C-N 3.31Å; R265-Q267 PolarHBondContact O-N 2.77Å; R265-R268 PolarHBondContact O-N 2.95Å; R265-L269 HydrophobicContact CG-CD1 4.44Å; R265-L269 WeakPolarHBondContact O-CG 3.45Å; R265-L269 PolarHBondContact O-N 3.38Å; R265-L269 VanDerWaalsContact O-N 3.12Å
266	K	83.1	Confident	78.2	Confident	105 Å²	105	74.8 Å²	74.8	46%	0.457	37%	0.373	S	S	.	.	H	α-helix	trans	-60.8	-40	175.8	-72.7	177.2	-176.2	174.7	0	111.7	F176 S262 I263 L269 A270	F176-K266 PolarHBondContact O-NZ 3.15Å; S262-K266 WeakPolarHBondContact O-CG 3.34Å; S262-K266 PolarHBondContact O-N 2.95Å; I263-K266 PolarHBondContact O-N 3.35Å; I263-K266 VanDerWaalsContact O-N 3.16Å; K266-L269 PolarHBondContact O-N 3.46Å; K266-A270 PolarHBondContact O-N 3.02Å
267	Q	80.2	Confident	76.3	Confident	47 Å²	47	82.9 Å²	82.9	22%	0.22	41%	0.412	C	S	.	.	H	α-helix	trans	-62.3	-44.5	175.6	-72.8	172.9	-11.3	0	0	112.6	I263 R264 R265 L269 A270 A271 Y340	I263-Q267 WeakPolarHBondContact O-CG 3.32Å; I263-Q267 PolarHBondContact O-N 3.42Å; R264-Q267 PolarHBondContact O-N 3.44Å; R265-Q267 VanDerWaalsContact C-N 3.31Å; R265-Q267 PolarHBondContact O-N 2.77Å; Q267-L269 VanDerWaalsContact C-N 3.33Å; Q267-L269 PolarHBondContact O-N 2.88Å; Q267-A270 PolarHBondContact O-N 3.18Å; Q267-A271 WeakPolarHBondContact O-CB 3.33Å; Q267-A271 PolarHBondContact O-N 2.84Å; Q267-Y340 HydrophobicContact CG-CE1 4.05Å
268	R	79.6	Confident	74.4	Confident	105 Å²	105	84.1 Å²	84.1	40%	0.396	43%	0.433	S	S	.	.	H	α-helix	trans	-62.3	-40.6	176.6	-71.4	-177.5	-167.2	169.9	6.5	112.3	R264 R265 A270 A271 N272	R264-R268 WeakPolarHBondContact O-CG 3.39Å; R264-R268 PolarHBondContact O-N 3.28Å; R265-R268 PolarHBondContact O-N 2.95Å; R268-A270 VanDerWaalsContact C-N 3.3Å; R268-A270 PolarHBondContact O-N 3.25Å; R268-A271 PolarHBondContact O-N 3.44Å; R268-N272 WeakPolarHBondContact O-CB 3.45Å; R268-N272 PolarHBondContact O-N 3.47Å
269	L	78.5	Confident	72.5	Confident	108 Å²	108	89.6 Å²	89.6	57%	0.565	46%	0.458	S	S	*	.	H	α-helix	trans	-63.5	-38.8	176.3	-70.1	170.4	0	0	0	111.3	R265 K266 Q267 V273	R265-L269 HydrophobicContact CG-CD1 4.44Å; R265-L269 WeakPolarHBondContact O-CG 3.45Å; R265-L269 PolarHBondContact O-N 3.38Å; R265-L269 VanDerWaalsContact O-N 3.12Å; K266-L269 PolarHBondContact O-N 3.46Å; Q267-L269 VanDerWaalsContact C-N 3.33Å; Q267-L269 PolarHBondContact O-N 2.88Å; L269-V273 WeakPolarHBondContact O-CG2 3.44Å
270	A	77.3	Confident	70.7	Confident	27 Å²	27	94.2 Å²	94.2	22%	0.223	49%	0.487	C	S	.	.	H	α-helix	trans	-70.7	-36.4	174.8	0	0	0	0	0	113.3	K266 Q267 R268 V273	K266-A270 PolarHBondContact O-N 3.02Å; Q267-A270 PolarHBondContact O-N 3.18Å; R268-A270 VanDerWaalsContact C-N 3.3Å; R268-A270 PolarHBondContact O-N 3.25Å; A270-V273 PolarHBondContact O-N 3.4Å
271	A	73.5	Confident	68.8	Low	53 Å²	53	102.4 Å²	102.4	44%	0.438	52%	0.522	S	S	.	.	H	α-helix	trans	-73.8	-36.5	-179.6	0	0	0	0	0	112.9	Q267 R268 V273 N274 Q275	Q267-A271 WeakPolarHBondContact O-CB 3.33Å; Q267-A271 PolarHBondContact O-N 2.84Å; R268-A271 PolarHBondContact O-N 3.44Å; A271-V273 PolarHBondContact O-N 2.84Å; A271-N274 CarbonylContact O-C 3.49Å; A271-N274 VanDerWaalsContact O-C 3.31Å; A271-N274 WeakPolarHBondContact O-CA 3.34Å; A271-N274 PolarHBondContact O-N 2.87Å; A271-Q275 PolarHBondContact O-N 3.41Å
272	N	69.9	Low	66.8	Low	106 Å²	106	104.2 Å²	104.2	57%	0.567	53%	0.533	S	S	*	.	H	α-helix	trans	-63.9	-24.7	174.5	-78.8	-1.2	0	0	0	112.5	R268 N274	R268-N272 WeakPolarHBondContact O-CB 3.45Å; R268-N272 PolarHBondContact O-N 3.47Å; N272-N274 VanDerWaalsContact C-N 3.28Å
273	V	68.1	Low	64.9	Low	117 Å²	117	106 Å²	106	71%	0.709	54%	0.539	S	S	*	.	H	α-helix	trans	-72.9	-24	171.2	175.9	0	0	0	0	111.5	L269 A270 A271	L269-V273 WeakPolarHBondContact O-CG2 3.44Å; A270-V273 PolarHBondContact O-N 3.4Å; A271-V273 PolarHBondContact O-N 2.84Å
274	N	62.2	Low	63.1	Low	96 Å²	96	111.3 Å²	111.3	51%	0.513	56%	0.559	S	S	.	*	T	Hydrogen-bonded Turn	trans	-112.2	27.6	-175.1	-72.9	0.8	0	0	0	112.9	A271 N272 N276	A271-N274 CarbonylContact O-C 3.49Å; A271-N274 VanDerWaalsContact O-C 3.31Å; A271-N274 WeakPolarHBondContact O-CA 3.34Å; A271-N274 PolarHBondContact O-N 2.87Å; N272-N274 VanDerWaalsContact C-N 3.28Å; N274-N276 VanDerWaalsContact C-N 3.34Å; N274-N276 PolarHBondContact O-N 3.19Å
275	Q	52	Low	61.2	Low	155 Å²	155	116.9 Å²	116.9	72%	0.724	58%	0.584	S	S	*	*			trans	-63.6	85.7	-170.2	-136.5	-176.6	7.1	0	0	112.6	A271	A271-Q275 PolarHBondContact O-N 3.41Å
276	N	46.7	Very low	59.5	Low	158 Å²	158	111.7 Å²	111.7	85%	0.845	57%	0.572	S	S	*	*			trans	-151.8	19.7	157.2	-124.6	8.4	0	0	0	115.2	N274	N274-N276 VanDerWaalsContact C-N 3.34Å; N274-N276 PolarHBondContact O-N 3.19Å
277	Q	48.5	Very low	57.8	Low	186 Å²	186	108.2 Å²	108.2	87%	0.869	56%	0.557	S	S	*	*			trans	-131.4	110	168.2	-84	-177.4	-25.6	0	0	111.5
278	G	47.9	Very low	56	Low	65 Å²	65	109.8 Å²	109.8	67%	0.67	57%	0.566	S	S	*	*			trans	-70.1	163.6	167.9	0	0	0	0	0	111.3
279	I	51.8	Low	54.4	Low	170 Å²	170	110.5 Å²	110.5	87%	0.872	57%	0.574	S	S	*	*			trans	104	57.9	-177.6	-50	155.8	0	0	0	112.9
280	T	50.4	Low	53.2	Low	98 Å²	98	106.1 Å²	106.1	60%	0.601	55%	0.553	S	S	*	*			trans	-138.3	21.7	164.3	5.5	0	0	0	0	113.4
281	K	45.6	Very low	51.8	Low	199 Å²	199	109 Å²	109	87%	0.865	56%	0.562	S	S	*	*	S	Bend	trans	-84.8	-24	178	-82.3	-175	175.9	178.5	0	114.1	F283 Y284	K281-F283 VanDerWaalsContact C-N 3.35Å; K281-F283 PolarHBondContact O-N 3.17Å; K281-Y284 PolarHBondContact O-N 3.23Å
282	F	46.1	Very low	50.6	Low	170 Å²	170	112.6 Å²	112.6	75%	0.746	57%	0.573	S	S	*	*	G	3₁₀ helix	trans	-69.4	-29.3	-175.7	-159.1	-106.2	0	0	0	113.6	Y284	F282-Y284 VanDerWaalsContact C-N 3.25Å; F282-Y284 PolarHBondContact O-N 3.33Å
283	F	48.1	Very low	49.7	Very low	56 Å²	56	109.7 Å²	109.7	25%	0.246	57%	0.568	C	S	.	*	G	3₁₀ helix	trans	-69.4	-9.3	-179.9	-91.8	-91.8	0	0	0	115.6	R264 K281 N322 Y326	R264-F283 VanDerWaalsContact NH2-C 3.33Å; R264-F283 PolarHBondContact NH2-O 2.9Å; K281-F283 VanDerWaalsContact C-N 3.35Å; K281-F283 PolarHBondContact O-N 3.17Å; F283-N322 HydrophobicContact CE1-CB 3.59Å; F283-N322 HydrophobicContact CZ-CB 3.65Å; F283-Y326 HydrophobicContact CE2-CD2 4.48Å; F283-Y326 HydrophobicContact CZ-CD2 4.21Å
284	Y	46.5	Very low	48.5	Very low	118 Å²	118	107.4 Å²	107.4	46%	0.463	55%	0.549	S	S	.	.	G	3₁₀ helix	trans	-82.2	-34.4	-173.7	-148.1	-86.4	0	0	0	112.6	K281 F282 L288	K281-Y284 PolarHBondContact O-N 3.23Å; F282-Y284 VanDerWaalsContact C-N 3.25Å; F282-Y284 PolarHBondContact O-N 3.33Å; Y284-L288 HydrophobicContact CE1-CD1 3.97Å; Y284-L288 HydrophobicContact CE1-CD2 4.47Å
285	F	44.2	Very low	47.4	Very low	157 Å²	157	112 Å²	112	69%	0.689	57%	0.565	S	S	*	*	H	α-helix	trans	-71.5	-38.8	-168.5	-165.4	-102.9	0	0	0	113	F287	F285-F287 PolarHBondContact O-N 2.92Å
286	C	49	Very low	46.8	Very low	49 Å²	49	113.7 Å²	113.7	33%	0.331	57%	0.57	S	S	.	*	H	α-helix	trans	-74.1	-26	-175.1	-68.9	0	0	0	0	114.5	I318	C286-I318 HydrophobicContact CB-CD1 4.34Å; C286-I318 HydrophobicContact CB-CG2 3.68Å
287	F	47.3	Very low	46.5	Very low	32 Å²	32	109.2 Å²	109.2	14%	0.14	55%	0.546	C	S	.	.	H	α-helix	trans	-90.4	-37.1	-176.5	-161.5	-90.8	0	0	0	112.7	V257 F260 F285 H289 A290 E291	V257-F287 HydrophobicContact CG1-CZ 4.48Å; F260-F287 HydrophobicContact CD1-CD2 4.38Å; F260-F287 HydrophobicContact CD1-CE1 4.29Å; F260-F287 AromaticContact CD1-CE2 3.69Å; F260-F287 HydrophobicContact CD1-CE2 3.69Å; F260-F287 AromaticContact CD1-CZ 3.63Å; F260-F287 HydrophobicContact CD1-CZ 3.63Å; F260-F287 HydrophobicContact CE1-CD1 4.49Å; F260-F287 AromaticContact CE1-CD2 3.73Å; F260-F287 HydrophobicContact CE1-CD2 3.73Å; F260-F287 HydrophobicContact CE1-CE1 4.29Å; F260-F287 AromaticContact CE1-CE2 3.49Å; F260-F287 HydrophobicContact CE1-CE2 3.49Å; F260-F287 VanDerWaalsContact CE1-CE2 3.49Å; F260-F287 HydrophobicContact CE1-CG 4.23Å; F260-F287 AromaticContact CE1-CZ 3.8Å; F260-F287 HydrophobicContact CE1-CZ 3.8Å; F260-F287 HydrophobicContact CZ-CD2 4.23Å; F260-F287 HydrophobicContact CZ-CE2 4.16Å; F285-F287 PolarHBondContact O-N 2.92Å; F287-H289 VanDerWaalsContact C-N 3.25Å; F287-H289 PolarHBondContact O-N 3.35Å; F287-A290 VanDerWaalsContact O-CB 3.28Å; F287-A290 WeakPolarHBondContact O-CB 3.46Å; F287-A290 PolarHBondContact O-N 3.49Å; F287-A290 VanDerWaalsContact O-N 3.09Å; F287-E291 HydrophobicContact CE1-CG 4.14Å; F287-E291 PolarHBondContact O-N 3.32Å
288	L	43.1	Very low	46.2	Very low	80 Å²	80	105.9 Å²	105.9	42%	0.419	54%	0.538	S	S	.	.	H	α-helix	trans	-66.4	-32.2	179	-149.2	86.6	0	0	0	111.8	Y284 A290 E291	Y284-L288 HydrophobicContact CE1-CD1 3.97Å; Y284-L288 HydrophobicContact CE1-CD2 4.47Å; L288-A290 PolarHBondContact O-N 2.88Å; L288-E291 PolarHBondContact O-N 3.03Å
289	H	46.4	Very low	45.7	Very low	121 Å²	121	111 Å²	111	56%	0.56	55%	0.549	S	S	*	.	H	α-helix	trans	-69	-19.6	176.1	-136	-68.9	0	0	0	113	F287	F287-H289 VanDerWaalsContact C-N 3.25Å; F287-H289 PolarHBondContact O-N 3.35Å
290	A	52.5	Low	45.2	Very low	16 Å²	16	111.3 Å²	111.3	13%	0.132	54%	0.544	C	S	.	.	H	α-helix	trans	-80.3	-41.5	176	0	0	0	0	0	112.9	F287 L288 H294 I315	F287-A290 VanDerWaalsContact O-CB 3.28Å; F287-A290 WeakPolarHBondContact O-CB 3.46Å; F287-A290 PolarHBondContact O-N 3.49Å; F287-A290 VanDerWaalsContact O-N 3.09Å; L288-A290 PolarHBondContact O-N 2.88Å; A290-H294 PolarHBondContact O-N 3.39Å; A290-I315 HydrophobicContact CB-CD1 3.27Å; A290-I315 HydrophobicContact CB-CG1 3.72Å
291	E	47.6	Very low	44.9	Very low	86 Å²	86	111.8 Å²	111.8	40%	0.402	55%	0.551	S	S	.	*	H	α-helix	trans	-70.1	-35.1	-176.2	-78.5	-173.2	157.8	0	0	112.8	F287 L288 G293 H294	F287-E291 HydrophobicContact CE1-CG 4.14Å; F287-E291 PolarHBondContact O-N 3.32Å; L288-E291 PolarHBondContact O-N 3.03Å; E291-G293 VanDerWaalsContact C-N 3.31Å; E291-G293 PolarHBondContact O-N 3.1Å; E291-H294 PolarHBondContact O-N 2.52Å
292	I	48.4	Very low	44.8	Very low	129 Å²	129	106.7 Å²	106.7	66%	0.662	53%	0.527	S	S	*	.	H	α-helix	trans	-70.9	-29	-178.4	-63	173.3	0	0	0	111.6
293	G	51.4	Low	44.8	Very low	45 Å²	45	109 Å²	109	46%	0.464	53%	0.533	S	S	.	.	H	α-helix	trans	-74.4	-36	176.6	0	0	0	0	0	113.6	E291	E291-G293 VanDerWaalsContact C-N 3.31Å; E291-G293 PolarHBondContact O-N 3.1Å
294	H	42.4	Very low	44.8	Very low	69 Å²	69	109.9 Å²	109.9	32%	0.319	54%	0.537	S	S	.	.	H	α-helix	trans	-80.2	-33.1	-167.5	-144.5	-84.1	0	0	0	113.8	A290 E291	A290-H294 PolarHBondContact O-N 3.39Å; E291-H294 PolarHBondContact O-N 2.52Å
295	F	39.2	Very low	45.2	Very low	192 Å²	192	106 Å²	106	84%	0.842	52%	0.524	S	S	*	.	H	α-helix	trans	-86.8	-23.3	-169.4	-135.8	-89.7	0	0	0	114.4	L297	F295-L297 VanDerWaalsContact C-N 3.3Å; F295-L297 PolarHBondContact O-N 3.05Å
296	K	39.9	Very low	45.4	Very low	192 Å²	192	108.5 Å²	108.5	84%	0.835	53%	0.529	S	S	*	.	T	Hydrogen-bonded Turn	trans	-83.7	-4	-178.1	-141	174.8	-176	-179.8	0	113.7
297	L	40.7	Very low	45.6	Very low	63 Å²	63	111.7 Å²	111.7	33%	0.33	54%	0.539	S	S	.	.			trans	-121.9	-3	-164.4	-126.3	84.1	0	0	0	115.9	F295 L299 K300 E304	F295-L297 VanDerWaalsContact C-N 3.3Å; F295-L297 PolarHBondContact O-N 3.05Å; L297-L299 PolarHBondContact O-N 3.09Å; L297-K300 PolarHBondContact O-N 3.32Å; L297-E304 HydrophobicContact CD2-CB 3.36Å; L297-E304 HydrophobicContact CD2-CG 3.59Å; L297-E304 HydrophobicContact CG-CB 4.48Å; L297-E304 HydrophobicContact CG-CG 4.44Å
298	V	41	Very low	46.1	Very low	117 Å²	117	112.8 Å²	112.8	71%	0.709	55%	0.546	S	S	*	.	T	Hydrogen-bonded Turn	trans	-63.3	-10.1	178.7	175.8	0	0	0	0	112.6
299	L	37.9	Very low	46.6	Very low	171 Å²	171	110.6 Å²	110.6	90%	0.895	54%	0.536	S	S	*	.	T	Hydrogen-bonded Turn	trans	-110.7	10.3	-179.2	-113.9	91.4	0	0	0	117.9	L297	L297-L299 PolarHBondContact O-N 3.09Å
300	K	41.8	Very low	47.1	Very low	177 Å²	177	111.1 Å²	111.1	77%	0.77	54%	0.538	S	S	*	.	S	Bend	trans	-129.6	65.3	175.1	-147.2	163.7	-175.2	176.5	0	113.6	L297	L297-K300 PolarHBondContact O-N 3.32Å
301	S	44.3	Very low	47.5	Very low	109 Å²	109	114.7 Å²	114.7	76%	0.762	55%	0.552	S	S	*	*			trans	15.2	111.6	159.7	-155.8	0	0	0	0	118.6	Y303	S301-Y303 VanDerWaalsContact C-N 3.34Å; S301-Y303 PolarHBondContact O-N 2.86Å
302	Y	42.1	Very low	48.1	Very low	92 Å²	92	111.5 Å²	111.5	36%	0.361	54%	0.537	S	S	.	.	S	Bend	trans	71.3	-36.3	143.6	-138.9	-98.7	0	0	0	120.1	E304 I305 K365 L366	Y302-E304 VanDerWaalsContact C-N 3.3Å; Y302-E304 PolarHBondContact O-N 3.19Å; Y302-I305 HydrophobicContact CD2-CD1 3.55Å; Y302-I305 HydrophobicContact CE2-CD1 3.81Å; Y302-I305 HydrophobicContact CG-CD1 3.99Å; Y302-K365 WeakPolarHBondContact OH-CB 3.3Å; Y302-L366 HydrophobicContact CE1-CD1 4.1Å
303	Y	46.1	Very low	48.5	Very low	218 Å²	218	107.4 Å²	107.4	86%	0.855	51%	0.514	S	S	*	.	T	Hydrogen-bonded Turn	trans	-75.8	-20.2	178.9	-121.3	-92.8	0	0	0	113.3	S301	S301-Y303 VanDerWaalsContact C-N 3.34Å; S301-Y303 PolarHBondContact O-N 2.86Å
304	E	49.8	Very low	49.1	Very low	74 Å²	74	107.5 Å²	107.5	35%	0.346	51%	0.508	S	S	.	.	T	Hydrogen-bonded Turn	trans	-91.5	-4.2	-178.8	-67.9	-67.3	165.5	0	0	114.6	L297 Y302 R306 Q307 I308	L297-E304 HydrophobicContact CD2-CB 3.36Å; L297-E304 HydrophobicContact CD2-CG 3.59Å; L297-E304 HydrophobicContact CG-CB 4.48Å; L297-E304 HydrophobicContact CG-CG 4.44Å; Y302-E304 VanDerWaalsContact C-N 3.3Å; Y302-E304 PolarHBondContact O-N 3.19Å; E304-R306 PolarHBondContact O-N 3.42Å; E304-Q307 PolarHBondContact O-N 3.47Å; E304-I308 PolarHBondContact O-N 2.9Å
305	I	53.9	Low	50	Low	36 Å²	36	106 Å²	106	19%	0.185	50%	0.502	C	S	.	.	H	α-helix	trans	-57.6	-28.3	178.6	-65.9	176.2	0	0	0	111.2	Y302 Q307 I308 V309 I362	Y302-I305 HydrophobicContact CD2-CD1 3.55Å; Y302-I305 HydrophobicContact CE2-CD1 3.81Å; Y302-I305 HydrophobicContact CG-CD1 3.99Å; I305-Q307 PolarHBondContact O-N 2.99Å; I305-I308 PolarHBondContact O-N 2.71Å; I305-V309 HydrophobicContact CG2-CG2 4.37Å; I305-V309 WeakPolarHBondContact O-CG2 3.08Å; I305-V309 PolarHBondContact O-N 3.22Å; I305-I362 HydrophobicContact CG2-CD1 3.93Å; I305-I362 HydrophobicContact CG2-CG1 3.87Å; I305-I362 HydrophobicContact CG2-CG2 4.24Å
306	R	48	Very low	50.9	Low	210 Å²	210	97.3 Å²	97.3	79%	0.792	46%	0.464	S	S	*	.	H	α-helix	trans	-60.6	-41.7	174.3	-169	-178.6	-171.6	-156.8	2.7	112.6	E304 H310	E304-R306 PolarHBondContact O-N 3.42Å; R306-H310 PolarHBondContact O-N 3.21Å
307	Q	52.9	Low	51.9	Low	116 Å²	116	92.4 Å²	92.4	54%	0.542	45%	0.446	S	S	.	.	H	α-helix	trans	-72.4	-38.4	177.8	-72.1	-162.8	8.6	0	0	111.3	E304 I305 V309 H310 H311	E304-Q307 PolarHBondContact O-N 3.47Å; I305-Q307 PolarHBondContact O-N 2.99Å; Q307-V309 PolarHBondContact O-N 3.48Å; Q307-H310 PolarHBondContact O-N 2.91Å; Q307-H311 WeakPolarHBondContact O-CB 3.23Å; Q307-H311 PolarHBondContact O-N 3.35Å
308	I	58.3	Low	52.9	Low	56 Å²	56	92 Å²	92	29%	0.287	44%	0.444	S	S	.	.	H	α-helix	trans	-60.6	-47.7	179.3	-63.9	172.9	0	0	0	110.6	E304 I305 H310 H311 F312	E304-I308 PolarHBondContact O-N 2.9Å; I305-I308 PolarHBondContact O-N 2.71Å; I308-H310 PolarHBondContact O-N 3.2Å; I308-H311 PolarHBondContact O-N 2.87Å; I308-F312 WeakPolarHBondContact O-CB 3.24Å; I308-F312 PolarHBondContact O-N 2.64Å
309	V	54.4	Low	53.8	Low	34 Å²	34	88.4 Å²	88.4	21%	0.206	42%	0.42	C	S	.	.	H	α-helix	trans	-62.5	-43.8	178.8	176.5	0	0	0	0	111.4	I305 Q307 F312 F313 I362	I305-V309 HydrophobicContact CG2-CG2 4.37Å; I305-V309 WeakPolarHBondContact O-CG2 3.08Å; I305-V309 PolarHBondContact O-N 3.22Å; Q307-V309 PolarHBondContact O-N 3.48Å; V309-F312 PolarHBondContact O-N 2.65Å; V309-F313 HydrophobicContact CG1-CD2 3.71Å; V309-F313 HydrophobicContact CG1-CE2 3.88Å; V309-F313 WeakPolarHBondContact O-CD2 3.5Å; V309-F313 PolarHBondContact O-N 2.92Å; V309-I362 HydrophobicContact CG2-CD1 3.21Å; V309-I362 HydrophobicContact CG2-CG1 4.39Å; V309-I362 HydrophobicContact CG2-CG2 4.31Å
310	H	56.1	Low	54.7	Low	132 Å²	132	81.5 Å²	81.5	61%	0.611	39%	0.386	S	S	*	.	H	α-helix	trans	-65.2	-45.6	-179.9	-162.5	-84.9	0	0	0	111.4	R306 Q307 I308 F312 F313 S314	R306-H310 PolarHBondContact O-N 3.21Å; Q307-H310 PolarHBondContact O-N 2.91Å; I308-H310 PolarHBondContact O-N 3.2Å; H310-F312 PolarHBondContact O-N 2.87Å; H310-F313 PolarHBondContact O-N 3.31Å; H310-S314 WeakPolarHBondContact O-CB 3.42Å; H310-S314 PolarHBondContact O-N 3.43Å; H310-S314 PolarHBondContact O-OG 2.91Å
311	H	60.6	Low	55.6	Low	90 Å²	90	78.3 Å²	78.3	42%	0.417	38%	0.377	S	S	.	.	H	α-helix	trans	-61.5	-45.3	175.1	-103.4	-71.9	0	0	0	111.5	Q307 I308 F313 S314 I315	Q307-H311 WeakPolarHBondContact O-CB 3.23Å; Q307-H311 PolarHBondContact O-N 3.35Å; I308-H311 PolarHBondContact O-N 2.87Å; H311-F313 VanDerWaalsContact C-N 3.34Å; H311-F313 PolarHBondContact O-N 3.44Å; H311-S314 PolarHBondContact O-N 3.46Å; H311-I315 WeakPolarHBondContact O-CB 3.49Å; H311-I315 WeakPolarHBondContact O-CD1 3.13Å; H311-I315 WeakPolarHBondContact O-CG1 3.16Å; H311-I315 PolarHBondContact O-N 3.48Å
312	F	60.6	Low	56.4	Low	19 Å²	19	74.5 Å²	74.5	8%	0.083	35%	0.348	C	S	.	.	H	α-helix	trans	-57.5	-47.5	178.2	-165.5	-71.4	0	0	0	111.2	F253 I308 V309 H310 I315 L316 S355	F253-F312 AromaticContact CD2-CE2 3.45Å; F253-F312 HydrophobicContact CD2-CE2 3.45Å; F253-F312 VanDerWaalsContact CD2-CE2 3.45Å; F253-F312 AromaticContact CD2-CZ 3.92Å; F253-F312 HydrophobicContact CD2-CZ 3.92Å; F253-F312 HydrophobicContact CE2-CD2 4.03Å; F253-F312 AromaticContact CE2-CE2 3.22Å; F253-F312 HydrophobicContact CE2-CE2 3.22Å; F253-F312 AromaticContact CE2-CZ 3.82Å; F253-F312 HydrophobicContact CE2-CZ 3.82Å; F253-F312 HydrophobicContact CG-CE2 4.32Å; F253-F312 HydrophobicContact CZ-CD2 4.35Å; F253-F312 AromaticContact CZ-CE2 3.93Å; F253-F312 HydrophobicContact CZ-CE2 3.93Å; I308-F312 WeakPolarHBondContact O-CB 3.24Å; I308-F312 PolarHBondContact O-N 2.64Å; V309-F312 PolarHBondContact O-N 2.65Å; H310-F312 PolarHBondContact O-N 2.87Å; F312-I315 PolarHBondContact O-N 3.27Å; F312-L316 HydrophobicContact CE1-CD1 4.21Å; F312-L316 HydrophobicContact CE1-CD2 4.49Å; F312-L316 WeakPolarHBondContact O-CB 3.13Å; F312-L316 PolarHBondContact O-N 2.65Å; F312-S355 VanDerWaalsContact CE1-CB 3.46Å; F312-S355 WeakPolarHBondContact CE1-OG 3.35Å
313	F	58.2	Low	57.1	Low	44 Å²	44	71.3 Å²	71.3	19%	0.193	34%	0.335	C	S	.	.	H	α-helix	trans	-64.8	-43.5	177.6	-94.3	-72.8	0	0	0	112.8	I2 V309 H310 H311 I315 L316 I317 I359	I2-F313 HydrophobicContact CD1-CD1 4.46Å; I2-F313 HydrophobicContact CD1-CE1 3.8Å; V309-F313 HydrophobicContact CG1-CD2 3.71Å; V309-F313 HydrophobicContact CG1-CE2 3.88Å; V309-F313 WeakPolarHBondContact O-CD2 3.5Å; V309-F313 PolarHBondContact O-N 2.92Å; H310-F313 PolarHBondContact O-N 3.31Å; H311-F313 VanDerWaalsContact C-N 3.34Å; H311-F313 PolarHBondContact O-N 3.44Å; F313-I315 VanDerWaalsContact C-N 3.3Å; F313-I315 PolarHBondContact O-N 3.23Å; F313-L316 PolarHBondContact O-N 2.97Å; F313-I317 WeakPolarHBondContact O-CB 3.44Å; F313-I317 VanDerWaalsContact O-CG1 3.31Å; F313-I317 WeakPolarHBondContact O-CG1 3.27Å; F313-I317 PolarHBondContact O-N 3.43Å; F313-I359 HydrophobicContact CE1-CD1 4.36Å; F313-I359 HydrophobicContact CE2-CD1 3.43Å; F313-I359 VanDerWaalsContact CE2-CD1 3.43Å; F313-I359 HydrophobicContact CE2-CG1 3.97Å; F313-I359 HydrophobicContact CZ-CD1 3.29Å; F313-I359 HydrophobicContact CZ-CG1 4.29Å
314	S	63.1	Low	57.4	Low	46 Å²	46	68.3 Å²	68.3	32%	0.322	33%	0.329	S	S	.	.	H	α-helix	trans	-59.3	-43	175.6	-68.9	0	0	0	0	111.2	H310 H311 I317 I318	H310-S314 WeakPolarHBondContact O-CB 3.42Å; H310-S314 PolarHBondContact O-N 3.43Å; H310-S314 PolarHBondContact O-OG 2.91Å; H311-S314 PolarHBondContact O-N 3.46Å; S314-I317 PolarHBondContact O-N 2.85Å; S314-I318 WeakPolarHBondContact O-CB 3.35Å; S314-I318 WeakPolarHBondContact O-CD1 3.18Å; S314-I318 WeakPolarHBondContact O-CG1 3.49Å; S314-I318 PolarHBondContact O-N 3.37Å
315	I	61.9	Low	57.6	Low	37 Å²	37	70.8 Å²	70.8	19%	0.19	34%	0.341	C	S	.	.	H	α-helix	trans	-63.1	-46.1	177.1	-66.2	156.3	0	0	0	110.8	A290 H311 F312 F313 I317 I318 L319	A290-I315 HydrophobicContact CB-CD1 3.27Å; A290-I315 HydrophobicContact CB-CG1 3.72Å; H311-I315 WeakPolarHBondContact O-CB 3.49Å; H311-I315 WeakPolarHBondContact O-CD1 3.13Å; H311-I315 WeakPolarHBondContact O-CG1 3.16Å; H311-I315 PolarHBondContact O-N 3.48Å; F312-I315 PolarHBondContact O-N 3.27Å; F313-I315 VanDerWaalsContact C-N 3.3Å; F313-I315 PolarHBondContact O-N 3.23Å; I315-I317 PolarHBondContact O-N 2.9Å; I315-I318 PolarHBondContact O-N 3.17Å; I315-L319 HydrophobicContact CG2-CD1 3.93Å; I315-L319 HydrophobicContact CG2-CG 4.42Å; I315-L319 WeakPolarHBondContact O-CG 3.39Å; I315-L319 PolarHBondContact O-N 3.49Å
316	L	58.2	Low	57.3	Low	10 Å²	10	75.3 Å²	75.3	5%	0.052	36%	0.357	C	S	.	.	H	α-helix	trans	-63.2	-42.5	-179.4	-155.4	75.5	0	0	0	111.5	F312 F313 L319 S320 A351 W352	F312-L316 HydrophobicContact CE1-CD1 4.21Å; F312-L316 HydrophobicContact CE1-CD2 4.49Å; F312-L316 WeakPolarHBondContact O-CB 3.13Å; F312-L316 PolarHBondContact O-N 2.65Å; F313-L316 PolarHBondContact O-N 2.97Å; L316-L319 PolarHBondContact O-N 3.09Å; L316-S320 PolarHBondContact O-N 2.86Å; L316-S320 PolarHBondContact O-OG 2.81Å; L316-A351 HydrophobicContact CD1-CB 3.57Å; L316-W352 HydrophobicContact CD2-CD2 4.18Å; L316-W352 HydrophobicContact CD2-CE3 3.28Å; L316-W352 HydrophobicContact CD2-CZ3 3.66Å; L316-W352 HydrophobicContact CG-CE3 4.27Å
317	I	59.7	Low	57.2	Low	89 Å²	89	69.4 Å²	69.4	46%	0.456	34%	0.34	S	S	.	.	H	α-helix	trans	-62.6	-45.1	175.9	-71.6	171.7	0	0	0	110.7	F313 S314 I315 L319 S320 L321	F313-I317 WeakPolarHBondContact O-CB 3.44Å; F313-I317 VanDerWaalsContact O-CG1 3.31Å; F313-I317 WeakPolarHBondContact O-CG1 3.27Å; F313-I317 PolarHBondContact O-N 3.43Å; S314-I317 PolarHBondContact O-N 2.85Å; I315-I317 PolarHBondContact O-N 2.9Å; I317-L319 VanDerWaalsContact C-N 3.34Å; I317-L319 PolarHBondContact O-N 3.49Å; I317-S320 PolarHBondContact O-N 3.31Å; I317-L321 HydrophobicContact CG2-CD1 3.76Å; I317-L321 HydrophobicContact CG2-CG 4.3Å; I317-L321 WeakPolarHBondContact O-CG 3.46Å; I317-L321 PolarHBondContact O-N 3.26Å
318	I	63.1	Low	56.9	Low	55 Å²	55	67 Å²	67	28%	0.282	35%	0.347	S	S	.	.	H	α-helix	trans	-63	-42.2	178.8	-68.9	163.4	0	0	0	110.9	C286 S314 I315 S320 L321 N322	C286-I318 HydrophobicContact CB-CD1 4.34Å; C286-I318 HydrophobicContact CB-CG2 3.68Å; S314-I318 WeakPolarHBondContact O-CB 3.35Å; S314-I318 WeakPolarHBondContact O-CD1 3.18Å; S314-I318 WeakPolarHBondContact O-CG1 3.49Å; S314-I318 PolarHBondContact O-N 3.37Å; I315-I318 PolarHBondContact O-N 3.17Å; I318-S320 PolarHBondContact O-N 2.95Å; I318-L321 PolarHBondContact O-N 3.48Å; I318-N322 WeakPolarHBondContact O-CB 3.48Å; I318-N322 VanDerWaalsContact O-CG 3.26Å; I318-N322 PolarHBondContact O-N 3.21Å; I318-N322 VanDerWaalsContact O-N 3.12Å
319	L	58.1	Low	56.3	Low	42 Å²	42	70.2 Å²	70.2	22%	0.22	36%	0.363	C	S	.	.	H	α-helix	trans	-63.4	-40.4	176.1	-72.1	171.1	0	0	0	112.1	F260 I315 L316 I317	F260-L319 HydrophobicContact CE2-CD2 4.12Å; F260-L319 HydrophobicContact CZ-CD2 4.07Å; I315-L319 HydrophobicContact CG2-CD1 3.93Å; I315-L319 HydrophobicContact CG2-CG 4.42Å; I315-L319 WeakPolarHBondContact O-CG 3.39Å; I315-L319 PolarHBondContact O-N 3.49Å; L316-L319 PolarHBondContact O-N 3.09Å; I317-L319 VanDerWaalsContact C-N 3.34Å; I317-L319 PolarHBondContact O-N 3.49Å
320	S	58.4	Low	55.7	Low	26 Å²	26	72.4 Å²	72.4	18%	0.182	39%	0.393	C	S	.	.	H	α-helix	trans	-68.1	-41.6	177.2	-72.9	0	0	0	0	113.1	L316 I317 I318 Y323	L316-S320 PolarHBondContact O-N 2.86Å; L316-S320 PolarHBondContact O-OG 2.81Å; I317-S320 PolarHBondContact O-N 3.31Å; I318-S320 PolarHBondContact O-N 2.95Å; S320-Y323 WeakPolarHBondContact O-CB 3.21Å; S320-Y323 PolarHBondContact O-N 3.4Å
321	L	60.2	Low	55	Low	110 Å²	110	69.4 Å²	69.4	58%	0.576	39%	0.387	S	S	*	.	H	α-helix	trans	-67	-39.8	180	-72.9	171.7	0	0	0	111.9	I317 I318 Y323 E324	I317-L321 HydrophobicContact CG2-CD1 3.76Å; I317-L321 HydrophobicContact CG2-CG 4.3Å; I317-L321 WeakPolarHBondContact O-CG 3.46Å; I317-L321 PolarHBondContact O-N 3.26Å; I318-L321 PolarHBondContact O-N 3.48Å; L321-Y323 PolarHBondContact O-N 2.85Å; L321-E324 PolarHBondContact O-N 3.44Å
322	N	59.9	Low	54.4	Low	28 Å²	28	72 Å²	72	15%	0.15	41%	0.409	C	S	.	.	H	α-helix	trans	-67.4	-15.9	179.5	-74.8	-5	0	0	0	113.7	F283 I318 Y326	F283-N322 HydrophobicContact CE1-CB 3.59Å; F283-N322 HydrophobicContact CZ-CB 3.65Å; I318-N322 WeakPolarHBondContact O-CB 3.48Å; I318-N322 VanDerWaalsContact O-CG 3.26Å; I318-N322 PolarHBondContact O-N 3.21Å; I318-N322 VanDerWaalsContact O-N 3.12Å; N322-Y326 PolarHBondContact O-N 2.93Å
323	Y	56.8	Low	53.8	Low	25 Å²	25	76.5 Å²	76.5	10%	0.098	43%	0.43	C	S	.	.	H	α-helix	trans	-73.3	-36.8	175.4	-178.1	-99.1	0	0	0	112.5	S320 L321 E325 Y326 L327 W344 Y405	S320-Y323 WeakPolarHBondContact O-CB 3.21Å; S320-Y323 PolarHBondContact O-N 3.4Å; L321-Y323 PolarHBondContact O-N 2.85Å; Y323-E325 VanDerWaalsContact C-N 3.33Å; Y323-E325 PolarHBondContact O-N 3.23Å; Y323-Y326 WeakPolarHBondContact O-CB 3.45Å; Y323-Y326 PolarHBondContact O-N 2.87Å; Y323-L327 HydrophobicContact CD1-CD1 4.21Å; Y323-L327 HydrophobicContact CE1-CD1 3.38Å; Y323-L327 PolarHBondContact O-N 3.34Å; Y323-W344 HydrophobicContact CD2-CB 4.08Å; Y323-W344 HydrophobicContact CD2-CG 4.36Å; Y323-W344 HydrophobicContact CE2-CB 3.74Å; Y323-W344 HydrophobicContact CE2-CG 4.32Å; Y323-Y405 HydrophobicContact CD1-CD1 4.04Å; Y323-Y405 AromaticContact CD1-CE1 3.91Å; Y323-Y405 HydrophobicContact CD1-CE1 3.91Å; Y323-Y405 AromaticContact CE1-CD1 3.81Å; Y323-Y405 HydrophobicContact CE1-CD1 3.81Å; Y323-Y405 HydrophobicContact CE1-CE1 4.16Å
324	E	54	Low	53.4	Low	155 Å²	155	78.3 Å²	78.3	72%	0.724	45%	0.453	S	S	*	.	H	α-helix	trans	-64.5	-39.2	178	-77.5	-162.2	165.8	0	0	111.7	L321 Y326 L327	L321-E324 PolarHBondContact O-N 3.44Å; E324-Y326 VanDerWaalsContact C-N 3.26Å; E324-Y326 PolarHBondContact O-N 3.45Å; E324-L327 PolarHBondContact O-N 3.37Å
325	E	52.5	Low	52.6	Low	127 Å²	127	84.5 Å²	84.5	59%	0.593	48%	0.477	S	S	*	.	H	α-helix	trans	-62.7	-35.5	175.9	-165.9	177.6	-177.6	0	0	111.7	Y323 G328	Y323-E325 VanDerWaalsContact C-N 3.33Å; Y323-E325 PolarHBondContact O-N 3.23Å; E325-G328 PolarHBondContact O-N 2.92Å
326	Y	49.1	Very low	51.8	Low	131 Å²	131	88.7 Å²	88.7	51%	0.514	49%	0.491	S	S	.	.	H	α-helix	trans	-70.8	-32.3	178.8	-137.4	-90.3	0	0	0	113.1	F283 N322 Y323 E324 G328 I329	F283-Y326 HydrophobicContact CE2-CD2 4.48Å; F283-Y326 HydrophobicContact CZ-CD2 4.21Å; N322-Y326 PolarHBondContact O-N 2.93Å; Y323-Y326 WeakPolarHBondContact O-CB 3.45Å; Y323-Y326 PolarHBondContact O-N 2.87Å; E324-Y326 VanDerWaalsContact C-N 3.26Å; E324-Y326 PolarHBondContact O-N 3.45Å; Y326-G328 PolarHBondContact O-N 2.8Å; Y326-I329 PolarHBondContact O-N 3.12Å
327	L	46.1	Very low	51.3	Low	86 Å²	86	91 Å²	91	45%	0.45	50%	0.503	S	S	.	.	H	α-helix	trans	-71.5	-17.9	-178.5	-138.8	127.1	0	0	0	112.6	Y323 E324	Y323-L327 HydrophobicContact CD1-CD1 4.21Å; Y323-L327 HydrophobicContact CE1-CD1 3.38Å; Y323-L327 PolarHBondContact O-N 3.34Å; E324-L327 PolarHBondContact O-N 3.37Å
328	G	46.8	Very low	50.8	Low	66 Å²	66	94 Å²	94	68%	0.68	52%	0.515	S	S	*	.	T	Hydrogen-bonded Turn	trans	-81.4	-17.1	178.7	0	0	0	0	0	115.2	E325 Y326 G330	E325-G328 PolarHBondContact O-N 2.92Å; Y326-G328 PolarHBondContact O-N 2.8Å; G328-G330 PolarHBondContact O-N 3.37Å
329	I	45.5	Very low	50.3	Low	122 Å²	122	95.7 Å²	95.7	63%	0.626	53%	0.528	S	S	*	.			trans	-91.7	89.8	-174.7	-54.7	177.5	0	0	0	109.4	Y326 S331	Y326-I329 PolarHBondContact O-N 3.12Å; I329-S331 PolarHBondContact O-N 2.75Å; I329-S331 VanDerWaalsContact O-N 3.12Å
330	G	41.3	Very low	50	Low	80 Å²	80	96.4 Å²	96.4	83%	0.825	53%	0.528	S	S	*	.			trans	-58.6	110.6	174	0	0	0	0	0	111.4	G328	G328-G330 PolarHBondContact O-N 3.37Å
331	S	41.8	Very low	50	Low	70 Å²	70	98.7 Å²	98.7	49%	0.49	54%	0.535	S	S	.	.			trans	-125.6	131.5	173.8	61	0	0	0	0	111.1	I329 H333 N337	I329-S331 PolarHBondContact O-N 2.75Å; I329-S331 VanDerWaalsContact O-N 3.12Å; S331-H333 VanDerWaalsContact C-N 3.31Å; S331-H333 PolarHBondContact O-N 3.01Å; S331-N337 PolarHBondContact O-ND2 3.49Å
332	T	47.4	Very low	49.9	Very low	143 Å²	143	96.3 Å²	96.3	88%	0.877	52%	0.519	S	S	*	.			trans	-85.8	34.6	-165.4	40.4	0	0	0	0	114.6
333	H	47.2	Very low	50.1	Low	114 Å²	114	95.8 Å²	95.8	53%	0.528	52%	0.516	S	S	.	.			trans	-111	87.9	174.1	-82.2	-61.3	0	0	0	111.5	S331 E335 N337	S331-H333 VanDerWaalsContact C-N 3.31Å; S331-H333 PolarHBondContact O-N 3.01Å; H333-E335 PolarHBondContact O-N 3.28Å; H333-N337 PolarHBondContact O-N 3.13Å; H333-N337 PolarHBondContact O-ND2 3.23Å
334	A	51	Low	50.7	Low	83 Å²	83	96.8 Å²	96.8	69%	0.686	52%	0.519	S	S	*	.	H	α-helix	trans	-56.5	-41.1	-170.9	0	0	0	0	0	114.6
335	E	45.6	Very low	51.3	Low	176 Å²	176	89.7 Å²	89.7	82%	0.822	49%	0.487	S	S	*	.	H	α-helix	trans	-84	-30.8	-170.8	-123.5	176.5	177.3	0	0	114.1	H333	H333-E335 PolarHBondContact O-N 3.28Å
336	R	46	Very low	52	Low	125 Å²	125	84 Å²	84	47%	0.472	46%	0.461	S	S	.	.	H	α-helix	trans	-78.8	-27.2	-180	-137	-175	-63.1	-145.7	1.3	111.6	Y340	R336-Y340 HydrophobicContact CG-CE2 4.06Å; R336-Y340 WeakPolarHBondContact O-CD2 3.31Å
337	N	47.8	Very low	53	Low	59 Å²	59	78.5 Å²	78.5	32%	0.316	44%	0.44	S	S	.	.	H	α-helix	trans	-75.4	-28.6	-175.9	-77.4	-11	0	0	0	113.2	S331 H333 V339 Y340 H341	S331-N337 PolarHBondContact O-ND2 3.49Å; H333-N337 PolarHBondContact O-N 3.13Å; H333-N337 PolarHBondContact O-ND2 3.23Å; N337-V339 PolarHBondContact O-N 2.94Å; N337-Y340 PolarHBondContact O-N 3.41Å; N337-H341 WeakPolarHBondContact O-CB 3.49Å; N337-H341 PolarHBondContact O-N 3.36Å
338	E	49.1	Very low	54.3	Low	151 Å²	151	74.9 Å²	74.9	71%	0.706	42%	0.421	S	S	*	.	H	α-helix	trans	-63	-43	-177	-72	-169.3	167.5	0	0	112.9
339	V	51.7	Low	55.4	Low	90 Å²	90	71.8 Å²	71.8	55%	0.545	39%	0.389	S	S	.	.	H	α-helix	trans	-66.6	-46	179.9	-168.7	0	0	0	0	110.4	N337 H341 Y342 E343	N337-V339 PolarHBondContact O-N 2.94Å; V339-H341 PolarHBondContact O-N 3.34Å; V339-Y342 PolarHBondContact O-N 2.87Å; V339-E343 VanDerWaalsContact CG1-OE1 3.3Å; V339-E343 WeakPolarHBondContact CG1-OE1 3.49Å; V339-E343 VanDerWaalsContact O-CG 3.28Å; V339-E343 WeakPolarHBondContact O-CG 3.1Å; V339-E343 PolarHBondContact O-N 3.25Å
340	Y	52.9	Low	56.6	Low	58 Å²	58	66.1 Å²	66.1	23%	0.227	36%	0.361	C	S	.	.	H	α-helix	trans	-68.6	-33.4	-177.9	-68.6	-59.9	0	0	0	113.6	Q267 R336 N337 Y342 E343	Q267-Y340 HydrophobicContact CG-CE1 4.05Å; R336-Y340 HydrophobicContact CG-CE2 4.06Å; R336-Y340 WeakPolarHBondContact O-CD2 3.31Å; N337-Y340 PolarHBondContact O-N 3.41Å; Y340-Y342 PolarHBondContact O-N 2.83Å; Y340-E343 WeakPolarHBondContact CD1-OE2 3.38Å; Y340-E343 PolarHBondContact O-N 3.48Å
341	H	57.6	Low	58.2	Low	73 Å²	73	63.2 Å²	63.2	34%	0.338	33%	0.329	S	S	.	.	H	α-helix	trans	-66.2	-29.6	-178.3	-133.5	-26.7	0	0	0	112.2	N337 V339 P345 K407	N337-H341 WeakPolarHBondContact O-CB 3.49Å; N337-H341 PolarHBondContact O-N 3.36Å; V339-H341 PolarHBondContact O-N 3.34Å; H341-P345 WeakPolarHBondContact O-CD 3.44Å; H341-P345 WeakPolarHBondContact O-CG 3.5Å; H341-K407 PolarHBondContact CE1-NZ 2.88Å; H341-K407 PolarHBondContact NE2-NZ 3.16Å
342	Y	58.9	Low	59.8	Low	61 Å²	61	63.1 Å²	63.1	24%	0.239	32%	0.318	C	S	.	.	H	α-helix	trans	-79.8	-33.6	176.6	-176.5	-93	0	0	0	112.8	Y73 V339 Y340 W344 V346	Y73-Y342 AromaticContact CD1-CE2 3.57Å; Y73-Y342 HydrophobicContact CD1-CE2 3.57Å; Y73-Y342 AromaticContact CD1-CZ 3.76Å; Y73-Y342 WeakPolarHBondContact CD1-OH 3.43Å; Y73-Y342 AromaticContact CE1-CE2 3.37Å; Y73-Y342 HydrophobicContact CE1-CE2 3.37Å; Y73-Y342 AromaticContact CE1-CZ 3.91Å; Y73-Y342 HydrophobicContact CG-CE2 4.5Å; V339-Y342 PolarHBondContact O-N 2.87Å; Y340-Y342 PolarHBondContact O-N 2.83Å; Y342-W344 PolarHBondContact O-N 3.23Å; Y342-V346 HydrophobicContact CD1-CG2 4.16Å; Y342-V346 HydrophobicContact CE1-CG2 3.76Å; Y342-V346 WeakPolarHBondContact O-CB 3.18Å; Y342-V346 WeakPolarHBondContact O-CG2 3.16Å
343	E	63.9	Low	61.2	Low	17 Å²	17	57 Å²	57	8%	0.079	28%	0.28	C	S	.	.	H	α-helix	trans	-64.5	-39.8	-173.5	-77.8	175.5	-173.8	0	0	114.4	F176 V339 Y340 V346 L347	F176-E343 HydrophobicContact CE1-CG 3.94Å; F176-E343 VanDerWaalsContact CE1-OE1 3.29Å; F176-E343 WeakPolarHBondContact CE1-OE1 3.35Å; F176-E343 HydrophobicContact CZ-CG 3.72Å; V339-E343 VanDerWaalsContact CG1-OE1 3.3Å; V339-E343 WeakPolarHBondContact CG1-OE1 3.49Å; V339-E343 VanDerWaalsContact O-CG 3.28Å; V339-E343 WeakPolarHBondContact O-CG 3.1Å; V339-E343 PolarHBondContact O-N 3.25Å; Y340-E343 WeakPolarHBondContact CD1-OE2 3.38Å; Y340-E343 PolarHBondContact O-N 3.48Å; E343-V346 WeakPolarHBondContact O-CB 3.1Å; E343-L347 WeakPolarHBondContact O-CG 3.5Å; E343-L347 PolarHBondContact O-N 3.48Å; E343-L347 VanDerWaalsContact O-N 3.14Å
344	W	68	Low	62.7	Low	45 Å²	45	51.6 Å²	51.6	17%	0.17	26%	0.255	C	S	.	.	H	α-helix	trans	-73.7	-52	-174	-89	107.7	0	0	0	115.4	F260 Y323 Y342 V346 L347 I348	F260-W344 HydrophobicContact CD2-CH2 4.28Å; F260-W344 HydrophobicContact CD2-CZ3 4.43Å; F260-W344 AromaticContact CE2-CH2 3.35Å; F260-W344 HydrophobicContact CE2-CH2 3.35Å; F260-W344 HydrophobicContact CE2-CZ2 4.13Å; F260-W344 AromaticContact CE2-CZ3 3.77Å; F260-W344 HydrophobicContact CE2-CZ3 3.77Å; F260-W344 HydrophobicContact CZ-CH2 4.1Å; Y323-W344 HydrophobicContact CD2-CB 4.08Å; Y323-W344 HydrophobicContact CD2-CG 4.36Å; Y323-W344 HydrophobicContact CE2-CB 3.74Å; Y323-W344 HydrophobicContact CE2-CG 4.32Å; Y342-W344 PolarHBondContact O-N 3.23Å; W344-V346 PolarHBondContact O-N 3.37Å; W344-V346 VanDerWaalsContact O-N 3.15Å; W344-L347 PolarHBondContact O-N 3.34Å; W344-I348 WeakPolarHBondContact O-CG1 3.36Å; W344-I348 PolarHBondContact O-N 3.15Å
345	P	67.4	Low	64	Low	7 Å²	7	47.9 Å²	47.9	5%	0.045	22%	0.223	C	C	.	.	H	α-helix	trans	-47.7	-43	173.1	-32.6	38.3	0	0	0	112.3	H341 I348 Q349 Y405	H341-P345 WeakPolarHBondContact O-CD 3.44Å; H341-P345 WeakPolarHBondContact O-CG 3.5Å; P345-I348 PolarHBondContact O-N 3.31Å; P345-Q349 WeakPolarHBondContact O-CB 3.48Å; P345-Q349 PolarHBondContact O-N 3.42Å; P345-Y405 VanDerWaalsContact CB-CB 3.46Å; P345-Y405 WeakPolarHBondContact CG-O 3.49Å
346	V	66.6	Low	65.7	Low	7 Å²	7	39.7 Å²	39.7	4%	0.042	19%	0.186	C	C	.	.	H	α-helix	trans	-60.7	-48.7	178.9	149.1	0	0	0	0	110.8	R172 Y342 E343 W344 A350	R172-V346 VanDerWaalsContact NE-CG1 3.33Å; R172-V346 VanDerWaalsContact NH1-C 3.33Å; R172-V346 VanDerWaalsContact NH1-CG1 3.3Å; R172-V346 PolarHBondContact NH1-O 3.43Å; Y342-V346 HydrophobicContact CD1-CG2 4.16Å; Y342-V346 HydrophobicContact CE1-CG2 3.76Å; Y342-V346 WeakPolarHBondContact O-CB 3.18Å; Y342-V346 WeakPolarHBondContact O-CG2 3.16Å; E343-V346 WeakPolarHBondContact O-CB 3.1Å; W344-V346 PolarHBondContact O-N 3.37Å; W344-V346 VanDerWaalsContact O-N 3.15Å; V346-A350 VanDerWaalsContact O-CB 3.3Å; V346-A350 WeakPolarHBondContact O-CB 3.16Å; V346-A350 PolarHBondContact O-N 2.99Å; V346-A350 VanDerWaalsContact O-N 3.12Å
347	L	70.5	Confident	67.3	Low	15 Å²	15	34.1 Å²	34.1	8%	0.079	17%	0.165	C	C	.	.	H	α-helix	trans	-66.4	-40.5	176.5	-72.8	171.7	0	0	0	113.2	Y256 I259 F260 I263 E343 W344 A350 A351	Y256-L347 HydrophobicContact CD1-CD2 3.71Å; Y256-L347 HydrophobicContact CE1-CD2 4.21Å; I259-L347 HydrophobicContact CB-CD2 4.4Å; I259-L347 HydrophobicContact CG2-CD2 3.79Å; F260-L347 HydrophobicContact CD2-CD1 4.48Å; I263-L347 HydrophobicContact CD1-CD1 3.77Å; E343-L347 WeakPolarHBondContact O-CG 3.5Å; E343-L347 PolarHBondContact O-N 3.48Å; E343-L347 VanDerWaalsContact O-N 3.14Å; W344-L347 PolarHBondContact O-N 3.34Å; L347-A350 VanDerWaalsContact O-CB 3.29Å; L347-A350 WeakPolarHBondContact O-CB 3.22Å; L347-A350 PolarHBondContact O-N 3.46Å; L347-A351 WeakPolarHBondContact O-CB 3.34Å; L347-A351 PolarHBondContact O-N 2.84Å
348	I	73.7	Confident	68.9	Low	11 Å²	11	32.9 Å²	32.9	6%	0.056	16%	0.158	C	C	.	.	H	α-helix	trans	-63.3	-47.4	178.2	-66.5	170.5	0	0	0	110.1	W344 P345 A350 A351 W352 V401 Y405	W344-I348 WeakPolarHBondContact O-CG1 3.36Å; W344-I348 PolarHBondContact O-N 3.15Å; P345-I348 PolarHBondContact O-N 3.31Å; I348-A350 PolarHBondContact O-N 3.03Å; I348-A351 PolarHBondContact O-N 3.12Å; I348-W352 WeakPolarHBondContact O-CB 3.35Å; I348-W352 PolarHBondContact O-N 3.31Å; I348-V401 HydrophobicContact CG2-CG1 4.13Å; I348-Y405 HydrophobicContact CD1-CD1 4.47Å; I348-Y405 HydrophobicContact CD1-CE1 4.16Å; I348-Y405 HydrophobicContact CG2-CD2 4.48Å; I348-Y405 HydrophobicContact CG2-CE2 3.96Å
349	Q	70.3	Confident	70.5	Confident	1 Å²	1	27.1 Å²	27.1	1%	0.005	13%	0.131	C	C	.	.	H	α-helix	trans	-55.2	-40.2	175.1	-179.7	-178.3	-37.8	0	0	112.5	P345 N353 L398 V401 H402	P345-Q349 WeakPolarHBondContact O-CB 3.48Å; P345-Q349 PolarHBondContact O-N 3.42Å; Q349-N353 PolarHBondContact O-N 3.09Å; Q349-L398 HydrophobicContact CG-CD1 3.19Å; Q349-V401 HydrophobicContact CB-CB 4.31Å; Q349-V401 HydrophobicContact CB-CG1 3.71Å; Q349-V401 HydrophobicContact CG-CB 4.43Å; Q349-V401 HydrophobicContact CG-CG1 4.35Å; Q349-H402 PolarHBondContact OE1-ND1 3.2Å
350	A	70.5	Confident	71.9	Confident	3 Å²	3	24.8 Å²	24.8	3%	0.025	11%	0.113	C	C	.	.	H	α-helix	trans	-69.9	-50.1	179	0	0	0	0	0	113.8	Y256 V346 L347 I348 W352 N353 C354	Y256-A350 HydrophobicContact CD1-CB 3.83Å; Y256-A350 HydrophobicContact CD2-CB 4.04Å; Y256-A350 HydrophobicContact CE1-CB 3.18Å; Y256-A350 HydrophobicContact CE2-CB 3.43Å; Y256-A350 VanDerWaalsContact CE2-CB 3.43Å; Y256-A350 HydrophobicContact CG-CB 4.25Å; Y256-A350 WeakPolarHBondContact OH-CB 3.34Å; V346-A350 VanDerWaalsContact O-CB 3.3Å; V346-A350 WeakPolarHBondContact O-CB 3.16Å; V346-A350 PolarHBondContact O-N 2.99Å; V346-A350 VanDerWaalsContact O-N 3.12Å; L347-A350 VanDerWaalsContact O-CB 3.29Å; L347-A350 WeakPolarHBondContact O-CB 3.22Å; L347-A350 PolarHBondContact O-N 3.46Å; I348-A350 PolarHBondContact O-N 3.03Å; A350-W352 PolarHBondContact O-N 2.95Å; A350-N353 PolarHBondContact O-N 2.89Å; A350-C354 PolarHBondContact O-N 2.86Å; A350-C354 PolarHBondContact O-SG 3.39Å
351	A	74.6	Confident	73.2	Confident	19 Å²	19	23 Å²	23	16%	0.157	11%	0.11	C	C	.	.	H	α-helix	trans	-57.1	-45.7	176.9	0	0	0	0	0	109.4	L316 L347 I348 N353 C354 S355	L316-A351 HydrophobicContact CD1-CB 3.57Å; L347-A351 WeakPolarHBondContact O-CB 3.34Å; L347-A351 PolarHBondContact O-N 2.84Å; I348-A351 PolarHBondContact O-N 3.12Å; A351-N353 PolarHBondContact O-N 3Å; A351-C354 WeakPolarHBondContact O-CB 3.17Å; A351-C354 PolarHBondContact O-N 2.98Å; A351-C354 VanDerWaalsContact O-N 3.17Å; A351-S355 PolarHBondContact O-N 3.42Å; A351-S355 PolarHBondContact O-OG 3.47Å
352	W	76.3	Confident	74.3	Confident	68 Å²	68	20.8 Å²	20.8	26%	0.258	10%	0.1	S	C	.	.	H	α-helix	trans	-63.3	-39.1	178.6	-162.8	-68.5	0	0	0	113.4	I2 L316 I348 A350 C354 S355 A356 V397 V401	I2-W352 HydrophobicContact CD1-CH2 3.24Å; I2-W352 HydrophobicContact CD1-CZ2 3.85Å; I2-W352 HydrophobicContact CD1-CZ3 4.18Å; I2-W352 HydrophobicContact CG1-CH2 4.29Å; L316-W352 HydrophobicContact CD2-CD2 4.18Å; L316-W352 HydrophobicContact CD2-CE3 3.28Å; L316-W352 HydrophobicContact CD2-CZ3 3.66Å; L316-W352 HydrophobicContact CG-CE3 4.27Å; I348-W352 WeakPolarHBondContact O-CB 3.35Å; I348-W352 PolarHBondContact O-N 3.31Å; A350-W352 PolarHBondContact O-N 2.95Å; W352-C354 VanDerWaalsContact C-N 3.34Å; W352-S355 PolarHBondContact O-N 2.82Å; W352-A356 VanDerWaalsContact O-CB 3.25Å; W352-A356 WeakPolarHBondContact O-CB 3.45Å; W352-A356 PolarHBondContact O-N 3.32Å; W352-V397 HydrophobicContact CG-CG1 4.03Å; W352-V397 VanDerWaalsContact NE1-CG1 3.33Å; W352-V401 HydrophobicContact CG-CG2 4.43Å
353	N	76.4	Confident	75.3	Confident	15 Å²	15	18.1 Å²	18.1	8%	0.08	9%	0.09	C	C	.	.	H	α-helix	trans	-62.5	-41.4	174	-81.7	-0.8	0	0	0	112.2	Q349 A350 A351 A356 L357 L398	Q349-N353 PolarHBondContact O-N 3.09Å; A350-N353 PolarHBondContact O-N 2.89Å; A351-N353 PolarHBondContact O-N 3Å; N353-A356 PolarHBondContact O-N 2.9Å; N353-L357 WeakPolarHBondContact O-CG 3.49Å; N353-L357 PolarHBondContact O-N 2.94Å; N353-L357 VanDerWaalsContact O-N 3.16Å; N353-L398 WeakPolarHBondContact ND2-CD1 2.97Å; N353-L398 WeakPolarHBondContact OD1-CB 3.28Å
354	C	78.5	Confident	76.2	Confident	0 Å²	0	21 Å²	21	0%	0	10%	0.102	C	C	.	.	H	α-helix	trans	-62.7	-49.9	176.5	-58	0	0	0	0	110.3	A350 A351 W352 A356 L357 E358	A350-C354 PolarHBondContact O-N 2.86Å; A350-C354 PolarHBondContact O-SG 3.39Å; A351-C354 WeakPolarHBondContact O-CB 3.17Å; A351-C354 PolarHBondContact O-N 2.98Å; A351-C354 VanDerWaalsContact O-N 3.17Å; W352-C354 VanDerWaalsContact C-N 3.34Å; C354-A356 VanDerWaalsContact C-N 3.32Å; C354-A356 PolarHBondContact O-N 3.27Å; C354-L357 PolarHBondContact O-N 2.97Å; C354-L357 VanDerWaalsContact O-N 3.11Å; C354-E358 PolarHBondContact O-N 3.46Å
355	S	78	Confident	76.9	Confident	4 Å²	4	23.3 Å²	23.3	3%	0.028	11%	0.114	C	C	.	.	H	α-helix	trans	-61.1	-41.5	178	1.3	0	0	0	0	111.8	F312 A351 W352 L357 E358 I359	F312-S355 VanDerWaalsContact CE1-CB 3.46Å; F312-S355 WeakPolarHBondContact CE1-OG 3.35Å; A351-S355 PolarHBondContact O-N 3.42Å; A351-S355 PolarHBondContact O-OG 3.47Å; W352-S355 PolarHBondContact O-N 2.82Å; S355-L357 PolarHBondContact O-N 2.84Å; S355-E358 PolarHBondContact O-N 3.44Å; S355-I359 WeakPolarHBondContact O-CB 3.48Å; S355-I359 WeakPolarHBondContact O-CD1 3.42Å; S355-I359 WeakPolarHBondContact O-CG1 3.2Å; S355-I359 PolarHBondContact O-N 3.38Å
356	A	81.4	Confident	77.6	Confident	5 Å²	5	25.8 Å²	25.8	4%	0.041	13%	0.126	C	C	.	.	H	α-helix	trans	-60.3	-35.2	178.4	0	0	0	0	0	112.4	W352 N353 C354 R360 Y390 V394	W352-A356 VanDerWaalsContact O-CB 3.25Å; W352-A356 WeakPolarHBondContact O-CB 3.45Å; W352-A356 PolarHBondContact O-N 3.32Å; N353-A356 PolarHBondContact O-N 2.9Å; C354-A356 VanDerWaalsContact C-N 3.32Å; C354-A356 PolarHBondContact O-N 3.27Å; A356-R360 PolarHBondContact O-N 2.98Å; A356-Y390 PolarHBondContact O-OH 2.98Å; A356-V394 HydrophobicContact CB-CG1 4.13Å; A356-V394 HydrophobicContact CB-CG2 4.17Å
357	L	79.3	Confident	78.3	Confident	7 Å²	7	28.1 Å²	28.1	4%	0.037	14%	0.138	C	C	.	.	H	α-helix	trans	-73.7	-40.2	176.5	-68	169.3	0	0	0	112	Y158 L162 P249 N353 C354 S355 R360	Y158-L357 HydrophobicContact CD2-CD2 4.41Å; Y158-L357 HydrophobicContact CE2-CD2 3.72Å; L162-L357 HydrophobicContact CD1-CD1 3.83Å; P249-L357 HydrophobicContact CG-CB 4.17Å; N353-L357 WeakPolarHBondContact O-CG 3.49Å; N353-L357 PolarHBondContact O-N 2.94Å; N353-L357 VanDerWaalsContact O-N 3.16Å; C354-L357 PolarHBondContact O-N 2.97Å; C354-L357 VanDerWaalsContact O-N 3.11Å; S355-L357 PolarHBondContact O-N 2.84Å; L357-R360 WeakPolarHBondContact O-CB 3.49Å
358	E	80.4	Confident	79.1	Confident	34 Å²	34	28.9 Å²	28.9	16%	0.159	14%	0.143	C	C	.	.	H	α-helix	trans	-70.5	-47.4	178.2	-72	169.6	-151.7	0	0	112.6	P249 C354 S355 R360 A361 I362	P249-E358 HydrophobicContact CB-CG 3.78Å; C354-E358 PolarHBondContact O-N 3.46Å; S355-E358 PolarHBondContact O-N 3.44Å; E358-R360 PolarHBondContact O-N 2.86Å; E358-A361 WeakPolarHBondContact O-CB 3.45Å; E358-A361 PolarHBondContact O-N 3.45Å; E358-I362 WeakPolarHBondContact O-CG1 3.14Å; E358-I362 PolarHBondContact O-N 2.93Å
359	I	82.9	Confident	79.8	Confident	29 Å²	29	31.7 Å²	31.7	15%	0.149	16%	0.162	C	C	.	.	H	α-helix	trans	-55.8	-37	177.3	-69.4	159.9	0	0	0	109.7	F313 S355 I362 I363 Y390	F313-I359 HydrophobicContact CE1-CD1 4.36Å; F313-I359 HydrophobicContact CE2-CD1 3.43Å; F313-I359 VanDerWaalsContact CE2-CD1 3.43Å; F313-I359 HydrophobicContact CE2-CG1 3.97Å; F313-I359 HydrophobicContact CZ-CD1 3.29Å; F313-I359 HydrophobicContact CZ-CG1 4.29Å; S355-I359 WeakPolarHBondContact O-CB 3.48Å; S355-I359 WeakPolarHBondContact O-CD1 3.42Å; S355-I359 WeakPolarHBondContact O-CG1 3.2Å; S355-I359 PolarHBondContact O-N 3.38Å; I359-I362 PolarHBondContact O-N 2.98Å; I359-I363 HydrophobicContact CG2-CD1 3.52Å; I359-I363 HydrophobicContact CG2-CG1 3.97Å; I359-I363 WeakPolarHBondContact O-CB 3.28Å; I359-I363 VanDerWaalsContact O-CG1 3.22Å; I359-I363 WeakPolarHBondContact O-CG1 3.27Å; I359-I363 PolarHBondContact O-N 2.72Å; I359-Y390 VanDerWaalsContact CB-OH 3.29Å; I359-Y390 WeakPolarHBondContact CB-OH 3.36Å; I359-Y390 HydrophobicContact CG2-CE2 4.02Å; I359-Y390 VanDerWaalsContact CG2-OH 3.23Å; I359-Y390 WeakPolarHBondContact CG2-OH 3.48Å
360	R	81.4	Confident	80.6	Confident	42 Å²	42	37.4 Å²	37.4	16%	0.158	19%	0.187	C	C	.	.	H	α-helix	trans	-56.3	-54	173.2	-169.6	-178.7	-173.3	-166.8	4	111.4	Y91 A356 L357 E358 I362 I363 F364 Y390	Y91-R360 PolarHBondContact OH-NH1 2.82Å; Y91-R360 VanDerWaalsContact OH-NH1 3.16Å; Y91-R360 PolarHBondContact OH-NH2 2.69Å; A356-R360 PolarHBondContact O-N 2.98Å; L357-R360 WeakPolarHBondContact O-CB 3.49Å; E358-R360 PolarHBondContact O-N 2.86Å; R360-I362 PolarHBondContact O-N 3.05Å; R360-I363 PolarHBondContact O-N 3.22Å; R360-F364 HydrophobicContact CG-CD2 3.71Å; R360-F364 HydrophobicContact CG-CE2 3.62Å; R360-F364 VanDerWaalsContact O-CD2 3.23Å; R360-F364 WeakPolarHBondContact O-CD2 3.38Å; R360-F364 PolarHBondContact O-N 3.23Å; R360-F364 VanDerWaalsContact O-N 3.08Å; R360-Y390 HydrophobicContact CB-CE1 3.95Å; R360-Y390 HydrophobicContact CG-CE1 4.26Å; R360-Y390 PolarHBondContact N-OH 2.93Å
361	A	80.4	Confident	81.3	Confident	19 Å²	19	38.7 Å²	38.7	16%	0.157	19%	0.194	C	C	.	.	H	α-helix	trans	-58.3	-39.6	-179.2	0	0	0	0	0	111.7	M246 E358 K365	M246-A361 HydrophobicContact CE-CB 4.05Å; E358-A361 WeakPolarHBondContact O-CB 3.45Å; E358-A361 PolarHBondContact O-N 3.45Å; A361-K365 WeakPolarHBondContact O-CB 3.22Å; A361-K365 PolarHBondContact O-N 2.87Å; A361-K365 VanDerWaalsContact O-N 3.08Å
362	I	80.5	Confident	81.9	Confident	27 Å²	27	40.5 Å²	40.5	14%	0.138	20%	0.2	C	C	.	.	H	α-helix	trans	-69	-44.7	178.8	-62.4	162.1	0	0	0	111.5	I305 V309 E358 I359 R360 F364 L366 I367	I305-I362 HydrophobicContact CG2-CD1 3.93Å; I305-I362 HydrophobicContact CG2-CG1 3.87Å; I305-I362 HydrophobicContact CG2-CG2 4.24Å; V309-I362 HydrophobicContact CG2-CD1 3.21Å; V309-I362 HydrophobicContact CG2-CG1 4.39Å; V309-I362 HydrophobicContact CG2-CG2 4.31Å; E358-I362 WeakPolarHBondContact O-CG1 3.14Å; E358-I362 PolarHBondContact O-N 2.93Å; I359-I362 PolarHBondContact O-N 2.98Å; R360-I362 PolarHBondContact O-N 3.05Å; I362-F364 PolarHBondContact O-N 3.23Å; I362-L366 HydrophobicContact CG2-CB 4.43Å; I362-L366 HydrophobicContact CG2-CD2 4.39Å; I362-L366 WeakPolarHBondContact O-CA 3.47Å; I362-L366 WeakPolarHBondContact O-CB 3.4Å; I362-L366 PolarHBondContact O-N 3.31Å; I362-I367 HydrophobicContact CG2-CD1 4.49Å; I362-I367 HydrophobicContact CG2-CG1 4.47Å; I362-I367 PolarHBondContact O-N 3.34Å
363	I	81	Confident	82.6	Confident	6 Å²	6	46.1 Å²	46.1	3%	0.031	23%	0.226	C	C	.	.	I	π-helix	trans	-56	-52.4	176.9	-74.6	168.5	0	0	0	109.8	I359 R360 I367 V368 F386 V387 Y390	I359-I363 HydrophobicContact CG2-CD1 3.52Å; I359-I363 HydrophobicContact CG2-CG1 3.97Å; I359-I363 WeakPolarHBondContact O-CB 3.28Å; I359-I363 VanDerWaalsContact O-CG1 3.22Å; I359-I363 WeakPolarHBondContact O-CG1 3.27Å; I359-I363 PolarHBondContact O-N 2.72Å; R360-I363 PolarHBondContact O-N 3.22Å; I363-I367 HydrophobicContact CG1-CD1 3.98Å; I363-I367 PolarHBondContact O-N 3.08Å; I363-V368 HydrophobicContact CG2-CG2 4.38Å; I363-V368 WeakPolarHBondContact O-CG2 3.43Å; I363-V368 PolarHBondContact O-N 2.91Å; I363-F386 HydrophobicContact CD1-CE1 4.37Å; I363-F386 HydrophobicContact CG2-CE1 4.42Å; I363-V387 HydrophobicContact CG2-CG2 4.08Å; I363-Y390 HydrophobicContact CD1-CD1 3.87Å; I363-Y390 HydrophobicContact CD1-CD2 4.04Å; I363-Y390 HydrophobicContact CD1-CE1 3.8Å; I363-Y390 HydrophobicContact CD1-CE2 3.97Å; I363-Y390 HydrophobicContact CD1-CG 3.99Å
364	F	81.5	Confident	83.1	Confident	76 Å²	76	49.9 Å²	49.9	33%	0.333	25%	0.246	S	C	.	.	I	π-helix	trans	-69.8	-39.1	-174	-81	-75.7	0	0	0	113.5	R360 I362 V387 V391	R360-F364 HydrophobicContact CG-CD2 3.71Å; R360-F364 HydrophobicContact CG-CE2 3.62Å; R360-F364 VanDerWaalsContact O-CD2 3.23Å; R360-F364 WeakPolarHBondContact O-CD2 3.38Å; R360-F364 PolarHBondContact O-N 3.23Å; R360-F364 VanDerWaalsContact O-N 3.08Å; I362-F364 PolarHBondContact O-N 3.23Å; F364-V387 HydrophobicContact CD1-CG1 4.27Å; F364-V387 HydrophobicContact CE1-CG1 3.26Å; F364-V387 HydrophobicContact CE2-CG1 4.02Å; F364-V387 HydrophobicContact CZ-CG1 3.1Å; F364-V391 HydrophobicContact CE2-CG2 4.18Å; F364-V391 HydrophobicContact CZ-CG2 4.16Å
365	K	82.8	Confident	83.6	Confident	94 Å²	94	54.7 Å²	54.7	41%	0.409	27%	0.266	S	S	.	.	I	π-helix	trans	-89.5	-34.9	-175.4	-73.7	-158.6	162.1	-167.9	0	114.6	F242 Y302 A361 P369	F242-K365 HydrophobicContact CD2-CD 4.25Å; F242-K365 VanDerWaalsContact CD2-CE 3.4Å; F242-K365 HydrophobicContact CE2-CD 3.4Å; F242-K365 VanDerWaalsContact CE2-CD 3.4Å; F242-K365 HydrophobicContact CZ-CD 3.64Å; Y302-K365 WeakPolarHBondContact OH-CB 3.3Å; A361-K365 WeakPolarHBondContact O-CB 3.22Å; A361-K365 PolarHBondContact O-N 2.87Å; A361-K365 VanDerWaalsContact O-N 3.08Å; K365-P369 WeakPolarHBondContact O-CG 3.17Å
366	L	82	Confident	84.1	Confident	59 Å²	59	56 Å²	56	31%	0.309	28%	0.281	S	S	.	.	I	π-helix	trans	-106.5	-54.2	-172.2	-173.6	68.3	0	0	0	111	Y302 I362 F370	Y302-L366 HydrophobicContact CE1-CD1 4.1Å; I362-L366 HydrophobicContact CG2-CB 4.43Å; I362-L366 HydrophobicContact CG2-CD2 4.39Å; I362-L366 WeakPolarHBondContact O-CA 3.47Å; I362-L366 WeakPolarHBondContact O-CB 3.4Å; I362-L366 PolarHBondContact O-N 3.31Å; L366-F370 WeakPolarHBondContact O-CB 3.44Å; L366-F370 PolarHBondContact O-N 2.9Å
367	I	82.8	Confident	84.5	Confident	57 Å²	57	61.8 Å²	61.8	29%	0.292	31%	0.307	S	S	.	.	I	π-helix	trans	-70.3	-45.2	-170.5	-57.7	-175.5	0	0	0	110.9	I362 I363 F370 L371	I362-I367 HydrophobicContact CG2-CD1 4.49Å; I362-I367 HydrophobicContact CG2-CG1 4.47Å; I362-I367 PolarHBondContact O-N 3.34Å; I363-I367 HydrophobicContact CG1-CD1 3.98Å; I363-I367 PolarHBondContact O-N 3.08Å; I367-F370 PolarHBondContact O-N 3.46Å; I367-L371 HydrophobicContact CG2-CD1 3.55Å; I367-L371 HydrophobicContact CG2-CG 3.95Å; I367-L371 WeakPolarHBondContact O-CB 3.17Å; I367-L371 VanDerWaalsContact O-CG 3.28Å; I367-L371 WeakPolarHBondContact O-CG 3.35Å; I367-L371 PolarHBondContact O-N 3.38Å
368	V	86.1	Confident	84.8	Confident	30 Å²	30	65.8 Å²	65.8	18%	0.182	33%	0.326	C	S	.	.	H	α-helix	trans	-59.9	-54.9	-177.2	163.5	0	0	0	0	112.3	I363 F370 L371 I372 L383 V387	I363-V368 HydrophobicContact CG2-CG2 4.38Å; I363-V368 WeakPolarHBondContact O-CG2 3.43Å; I363-V368 PolarHBondContact O-N 2.91Å; V368-F370 VanDerWaalsContact C-N 3.31Å; V368-F370 PolarHBondContact O-N 3.48Å; V368-L371 PolarHBondContact O-N 3.22Å; V368-I372 HydrophobicContact CG1-CD1 3.98Å; V368-I372 WeakPolarHBondContact O-CG1 3.22Å; V368-I372 PolarHBondContact O-N 3.09Å; V368-I372 VanDerWaalsContact O-N 3.15Å; V368-L383 HydrophobicContact CB-CD2 4.06Å; V368-L383 HydrophobicContact CG1-CD2 3.79Å; V368-L383 HydrophobicContact CG2-CD1 4Å; V368-L383 HydrophobicContact CG2-CD2 3.92Å; V368-L383 HydrophobicContact CG2-CG 4.02Å; V368-V387 HydrophobicContact CG2-CG2 4.04Å
369	P	88.7	Confident	85.1	Confident	71 Å²	71	64.5 Å²	64.5	46%	0.461	32%	0.32	S	S	.	.	H	α-helix	trans	-63.9	-35.6	178.3	-23.1	35.2	0	0	0	113.2	K365 I372 K373	K365-P369 WeakPolarHBondContact O-CG 3.17Å; P369-I372 PolarHBondContact O-N 3.36Å; P369-K373 PolarHBondContact O-N 3.24Å
370	F	86.1	Confident	85.5	Confident	120 Å²	120	64.8 Å²	64.8	53%	0.526	32%	0.322	S	S	.	.	H	α-helix	trans	-64.8	-45.6	179.1	177.3	-102	0	0	0	112.2	L366 I367 V368 I372 K373 I374	L366-F370 WeakPolarHBondContact O-CB 3.44Å; L366-F370 PolarHBondContact O-N 2.9Å; I367-F370 PolarHBondContact O-N 3.46Å; V368-F370 VanDerWaalsContact C-N 3.31Å; V368-F370 PolarHBondContact O-N 3.48Å; F370-I372 VanDerWaalsContact C-N 3.35Å; F370-K373 WeakPolarHBondContact O-CB 3.38Å; F370-K373 PolarHBondContact O-N 3.29Å; F370-I374 HydrophobicContact CD1-CD1 3.94Å; F370-I374 HydrophobicContact CD2-CD1 4.48Å; F370-I374 HydrophobicContact CE1-CD1 3.3Å; F370-I374 HydrophobicContact CE1-CG1 4.49Å; F370-I374 HydrophobicContact CE2-CD1 3.91Å; F370-I374 HydrophobicContact CZ-CD1 3.3Å; F370-I374 HydrophobicContact CZ-CG1 4.41Å; F370-I374 PolarHBondContact O-N 2.86Å
371	L	86.2	Confident	85.9	Confident	31 Å²	31	63 Å²	63	16%	0.162	32%	0.315	C	S	.	.	H	α-helix	trans	-64.7	-40.9	177.7	-70	176.9	0	0	0	111.2	I367 V368 K373 I374 F375 I379 L383	I367-L371 HydrophobicContact CG2-CD1 3.55Å; I367-L371 HydrophobicContact CG2-CG 3.95Å; I367-L371 WeakPolarHBondContact O-CB 3.17Å; I367-L371 VanDerWaalsContact O-CG 3.28Å; I367-L371 WeakPolarHBondContact O-CG 3.35Å; I367-L371 PolarHBondContact O-N 3.38Å; V368-L371 PolarHBondContact O-N 3.22Å; L371-K373 PolarHBondContact O-N 2.87Å; L371-I374 PolarHBondContact O-N 3.5Å; L371-I374 VanDerWaalsContact O-N 3.12Å; L371-F375 HydrophobicContact CD2-CD2 4.23Å; L371-F375 HydrophobicContact CD2-CE2 3.93Å; L371-F375 PolarHBondContact O-N 3.4Å; L371-I379 HydrophobicContact CB-CD1 3.4Å; L371-I379 VanDerWaalsContact CB-CD1 3.4Å; L371-I379 VanDerWaalsContact O-CD1 3.27Å; L371-I379 WeakPolarHBondContact O-CD1 3.35Å; L371-L383 HydrophobicContact CD1-CD1 3.93Å
372	I	87.7	Confident	86.3	Confident	57 Å²	57	63.1 Å²	63.1	29%	0.292	31%	0.314	S	S	.	.	H	α-helix	trans	-62.2	-36.9	177	-67.1	167.6	0	0	0	110.3	V368 P369 F370 I374 G376 I379 I380 L383	V368-I372 HydrophobicContact CG1-CD1 3.98Å; V368-I372 WeakPolarHBondContact O-CG1 3.22Å; V368-I372 PolarHBondContact O-N 3.09Å; V368-I372 VanDerWaalsContact O-N 3.15Å; P369-I372 PolarHBondContact O-N 3.36Å; F370-I372 VanDerWaalsContact C-N 3.35Å; I372-I374 VanDerWaalsContact C-N 3.33Å; I372-I374 PolarHBondContact O-N 3.42Å; I372-G376 CarbonylContact O-C 3.31Å; I372-G376 WeakPolarHBondContact O-CA 3.35Å; I372-G376 PolarHBondContact O-N 3.14Å; I372-I379 HydrophobicContact CG1-CD1 4.35Å; I372-I380 HydrophobicContact CD1-CG1 4.3Å; I372-I380 HydrophobicContact CG1-CG1 4.27Å; I372-L383 HydrophobicContact CD1-CD2 4.33Å; I372-L383 HydrophobicContact CG1-CD2 4.14Å
373	K	89.9	Confident	86.8	Confident	185 Å²	185	62.2 Å²	62.2	80%	0.804	31%	0.309	S	S	*	.	H	α-helix	trans	-65	-34	175.6	-175.3	177.4	178.1	-180	0	113.1	P369 F370 L371	P369-K373 PolarHBondContact O-N 3.24Å; F370-K373 WeakPolarHBondContact O-CB 3.38Å; F370-K373 PolarHBondContact O-N 3.29Å; L371-K373 PolarHBondContact O-N 2.87Å
374	I	88.1	Confident	87.3	Confident	95 Å²	95	62 Å²	62	49%	0.487	31%	0.309	S	S	.	.	H	α-helix	trans	-82.9	-47.6	-177.3	-69.9	177.8	0	0	0	111.8	F370 L371 I372	F370-I374 HydrophobicContact CD1-CD1 3.94Å; F370-I374 HydrophobicContact CD2-CD1 4.48Å; F370-I374 HydrophobicContact CE1-CD1 3.3Å; F370-I374 HydrophobicContact CE1-CG1 4.49Å; F370-I374 HydrophobicContact CE2-CD1 3.91Å; F370-I374 HydrophobicContact CZ-CD1 3.3Å; F370-I374 HydrophobicContact CZ-CG1 4.41Å; F370-I374 PolarHBondContact O-N 2.86Å; L371-I374 PolarHBondContact O-N 3.5Å; L371-I374 VanDerWaalsContact O-N 3.12Å; I372-I374 VanDerWaalsContact C-N 3.33Å; I372-I374 PolarHBondContact O-N 3.42Å
375	F	87.4	Confident	87.8	Confident	100 Å²	100	59.1 Å²	59.1	44%	0.439	30%	0.297	S	S	.	.	H	α-helix	trans	-104.5	3.5	-170.8	-61.7	-79.9	0	0	0	113.2	L371 I379	L371-F375 HydrophobicContact CD2-CD2 4.23Å; L371-F375 HydrophobicContact CD2-CE2 3.93Å; L371-F375 PolarHBondContact O-N 3.4Å; F375-I379 HydrophobicContact CB-CB 4.26Å; F375-I379 HydrophobicContact CB-CD1 4.1Å; F375-I379 HydrophobicContact CB-CG1 3.97Å; F375-I379 HydrophobicContact CB-CG2 3.33Å; F375-I379 HydrophobicContact CD2-CD1 4.3Å; F375-I379 HydrophobicContact CD2-CG2 4.4Å; F375-I379 HydrophobicContact CG-CG2 3.91Å
376	G	90	Very high	88.1	Confident	33 Å²	33	56.7 Å²	56.7	34%	0.34	29%	0.287	S	S	.	.	G	3₁₀ helix	trans	70.9	-162	-176.8	0	0	0	0	0	113.4	I372 E378 I379	I372-G376 CarbonylContact O-C 3.31Å; I372-G376 WeakPolarHBondContact O-CA 3.35Å; I372-G376 PolarHBondContact O-N 3.14Å; G376-E378 VanDerWaalsContact C-N 3.28Å; G376-E378 PolarHBondContact O-N 2.83Å; G376-I379 WeakPolarHBondContact O-CG1 3.18Å
377	E	88.7	Confident	88.5	Confident	125 Å²	125	54.5 Å²	54.5	58%	0.584	28%	0.276	S	S	*	.	G	3₁₀ helix	trans	-75.7	-15	-177.7	-64.3	-166.5	166.3	0	0	113.4	F28 I379 I380	F28-E377 HydrophobicContact CD2-CB 4.23Å; F28-E377 HydrophobicContact CE2-CB 4.14Å; E377-I379 VanDerWaalsContact C-N 3.25Å; E377-I379 PolarHBondContact O-N 3.06Å; E377-I380 HydrophobicContact CB-CD1 3.72Å; E377-I380 HydrophobicContact CG-CD1 3.97Å; E377-I380 VanDerWaalsContact O-CB 3.22Å; E377-I380 WeakPolarHBondContact O-CB 3.4Å; E377-I380 WeakPolarHBondContact O-CD1 3.25Å; E377-I380 WeakPolarHBondContact O-CG1 3.24Å; E377-I380 PolarHBondContact O-N 2.81Å; E377-I380 VanDerWaalsContact O-N 3.09Å
378	E	85.4	Confident	89	Confident	91 Å²	91	51.9 Å²	51.9	43%	0.425	26%	0.262	S	S	.	.	G	3₁₀ helix	trans	-59.9	-33.8	-177.5	-68.5	173.4	-166.3	0	0	112.9	F28 G376 I380	F28-E378 HydrophobicContact CE1-CG 4.33Å; F28-E378 HydrophobicContact CE2-CG 4.4Å; F28-E378 HydrophobicContact CZ-CB 4.38Å; F28-E378 HydrophobicContact CZ-CG 3.69Å; G376-E378 VanDerWaalsContact C-N 3.28Å; G376-E378 PolarHBondContact O-N 2.83Å; E378-I380 VanDerWaalsContact C-N 3.28Å; E378-I380 PolarHBondContact O-N 3.44Å
379	I	88.7	Confident	89.3	Confident	7 Å²	7	51 Å²	51	4%	0.036	26%	0.258	C	S	.	.	G	3₁₀ helix	trans	-81	-4.1	-179.1	61.6	150.8	0	0	0	114.1	L371 I372 F375 G376 E377 I381 P382 L383	L371-I379 HydrophobicContact CB-CD1 3.4Å; L371-I379 VanDerWaalsContact CB-CD1 3.4Å; L371-I379 VanDerWaalsContact O-CD1 3.27Å; L371-I379 WeakPolarHBondContact O-CD1 3.35Å; I372-I379 HydrophobicContact CG1-CD1 4.35Å; F375-I379 HydrophobicContact CB-CB 4.26Å; F375-I379 HydrophobicContact CB-CD1 4.1Å; F375-I379 HydrophobicContact CB-CG1 3.97Å; F375-I379 HydrophobicContact CB-CG2 3.33Å; F375-I379 HydrophobicContact CD2-CD1 4.3Å; F375-I379 HydrophobicContact CD2-CG2 4.4Å; F375-I379 HydrophobicContact CG-CG2 3.91Å; G376-I379 WeakPolarHBondContact O-CG1 3.18Å; E377-I379 VanDerWaalsContact C-N 3.25Å; E377-I379 PolarHBondContact O-N 3.06Å; I379-I381 VanDerWaalsContact C-N 3.3Å; I379-I381 PolarHBondContact O-N 3.09Å; I379-P382 WeakPolarHBondContact O-CD 3.49Å; I379-L383 HydrophobicContact CD1-CD2 4.31Å; I379-L383 WeakPolarHBondContact O-CB 2.91Å; I379-L383 PolarHBondContact O-N 2.71Å
380	I	90.1	Very high	89.4	Confident	36 Å²	36	49.4 Å²	49.4	19%	0.185	24%	0.242	C	C	.	.	H	α-helix	trans	-58.3	-43.5	-173.4	-74.1	173.9	0	0	0	111.2	N220 I372 E377 E378 G384	N220-I380 HydrophobicContact CB-CG2 3.38Å; I372-I380 HydrophobicContact CD1-CG1 4.3Å; I372-I380 HydrophobicContact CG1-CG1 4.27Å; E377-I380 HydrophobicContact CB-CD1 3.72Å; E377-I380 HydrophobicContact CG-CD1 3.97Å; E377-I380 VanDerWaalsContact O-CB 3.22Å; E377-I380 WeakPolarHBondContact O-CB 3.4Å; E377-I380 WeakPolarHBondContact O-CD1 3.25Å; E377-I380 WeakPolarHBondContact O-CG1 3.24Å; E377-I380 PolarHBondContact O-N 2.81Å; E377-I380 VanDerWaalsContact O-N 3.09Å; E378-I380 VanDerWaalsContact C-N 3.28Å; E378-I380 PolarHBondContact O-N 3.44Å; I380-G384 PolarHBondContact O-N 3.5Å
381	I	89.8	Confident	89.6	Confident	4 Å²	4	44 Å²	44	2%	0.021	22%	0.219	C	C	.	.	H	α-helix	trans	-67.1	-55.6	179.6	-67.7	169.2	0	0	0	111	F28 I30 A38 I379 L383 G384 I385	F28-I381 HydrophobicContact CB-CD1 4.21Å; I30-I381 HydrophobicContact CB-CD1 4.27Å; I30-I381 HydrophobicContact CB-CG2 4.5Å; I30-I381 HydrophobicContact CD1-CG2 3.89Å; I30-I381 HydrophobicContact CG1-CG2 4.09Å; A38-I381 HydrophobicContact CB-CG2 4.47Å; I379-I381 VanDerWaalsContact C-N 3.3Å; I379-I381 PolarHBondContact O-N 3.09Å; I381-L383 PolarHBondContact O-N 3.24Å; I381-G384 PolarHBondContact O-N 3.47Å; I381-G384 VanDerWaalsContact O-N 3.08Å; I381-I385 HydrophobicContact CG2-CD1 4.24Å; I381-I385 WeakPolarHBondContact O-CG1 3.34Å; I381-I385 PolarHBondContact O-N 2.78Å
382	P	89.7	Confident	90	Very high	21 Å²	21	42.5 Å²	42.5	14%	0.136	21%	0.211	C	C	.	.	H	α-helix	trans	-52.9	-39.6	174.5	-28.3	33.2	0	0	0	113.7	L13 N16 I379 I385 F386	L13-P382 HydrophobicContact CD2-CB 3.48Å; L13-P382 VanDerWaalsContact CD2-CB 3.48Å; N16-P382 HydrophobicContact CB-CG 4.2Å; I379-P382 WeakPolarHBondContact O-CD 3.49Å; P382-I385 PolarHBondContact O-N 3.34Å; P382-F386 WeakPolarHBondContact O-CB 3.49Å; P382-F386 PolarHBondContact O-N 3.45Å
383	L	89.7	Confident	90.2	Very high	8 Å²	8	43.2 Å²	43.2	4%	0.042	22%	0.216	C	C	.	.	H	α-helix	trans	-66.5	-40.9	177.9	-173.8	60.7	0	0	0	111.9	V368 L371 I372 I379 I381 F386 V387	V368-L383 HydrophobicContact CB-CD2 4.06Å; V368-L383 HydrophobicContact CG1-CD2 3.79Å; V368-L383 HydrophobicContact CG2-CD1 4Å; V368-L383 HydrophobicContact CG2-CD2 3.92Å; V368-L383 HydrophobicContact CG2-CG 4.02Å; L371-L383 HydrophobicContact CD1-CD1 3.93Å; I372-L383 HydrophobicContact CD1-CD2 4.33Å; I372-L383 HydrophobicContact CG1-CD2 4.14Å; I379-L383 HydrophobicContact CD1-CD2 4.31Å; I379-L383 WeakPolarHBondContact O-CB 2.91Å; I379-L383 PolarHBondContact O-N 2.71Å; I381-L383 PolarHBondContact O-N 3.24Å; L383-F386 HydrophobicContact CD1-CD1 4.37Å; L383-F386 PolarHBondContact O-N 2.72Å; L383-V387 HydrophobicContact CD1-CG2 4.39Å; L383-V387 WeakPolarHBondContact O-CB 3.47Å; L383-V387 VanDerWaalsContact O-CG2 3.23Å; L383-V387 WeakPolarHBondContact O-CG2 3.48Å; L383-V387 PolarHBondContact O-N 2.75Å
384	G	91.6	Very high	90.1	Very high	3 Å²	3	35.3 Å²	35.3	3%	0.031	18%	0.183	C	C	.	.	H	α-helix	trans	-61	-42.9	172.4	0	0	0	0	0	112.6	I380 I381 N388	I380-G384 PolarHBondContact O-N 3.5Å; I381-G384 PolarHBondContact O-N 3.47Å; I381-G384 VanDerWaalsContact O-N 3.08Å; G384-N388 PolarHBondContact O-N 3.34Å; G384-N388 VanDerWaalsContact O-N 3.09Å; G384-N388 PolarHBondContact O-ND2 2.94Å
385	I	91.8	Very high	90.4	Very high	14 Å²	14	30.8 Å²	30.8	7%	0.072	16%	0.16	C	C	.	.	H	α-helix	trans	-60.4	-48.9	173.7	-61.6	171.9	0	0	0	110.2	A38 A42 L45 F46 L221 I381 P382 V387 N388 S389	A38-I385 HydrophobicContact CB-CD1 4.47Å; A42-I385 HydrophobicContact CB-CD1 3.84Å; A42-I385 HydrophobicContact CB-CG1 3.83Å; A42-I385 HydrophobicContact CB-CG2 4.33Å; L45-I385 HydrophobicContact CD2-CG2 4.01Å; F46-I385 HydrophobicContact CE1-CG2 4.11Å; F46-I385 WeakPolarHBondContact CE1-O 3.39Å; F46-I385 HydrophobicContact CZ-CG2 4.45Å; L221-I385 HydrophobicContact CD1-CG1 3.51Å; I381-I385 HydrophobicContact CG2-CD1 4.24Å; I381-I385 WeakPolarHBondContact O-CG1 3.34Å; I381-I385 PolarHBondContact O-N 2.78Å; P382-I385 PolarHBondContact O-N 3.34Å; I385-V387 PolarHBondContact O-N 2.78Å; I385-N388 PolarHBondContact O-N 2.9Å; I385-S389 VanDerWaalsContact O-CB 3.3Å; I385-S389 WeakPolarHBondContact O-CB 3.31Å; I385-S389 PolarHBondContact O-N 3.19Å; I385-S389 PolarHBondContact O-OG 2.87Å
386	F	90	Very high	90.6	Very high	44 Å²	44	26 Å²	26	19%	0.193	14%	0.139	C	C	.	.	H	α-helix	trans	-59.3	-49.2	-179.8	170.6	-106.6	0	0	0	111.9	I9 I363 P382 L383 N388 S389 Y390	I9-F386 HydrophobicContact CD1-CD2 4Å; I9-F386 HydrophobicContact CD1-CE2 3.4Å; I9-F386 VanDerWaalsContact CD1-CE2 3.4Å; I9-F386 HydrophobicContact CD1-CZ 4.32Å; I9-F386 HydrophobicContact CG1-CD2 4.09Å; I9-F386 HydrophobicContact CG1-CE2 4.01Å; I9-F386 HydrophobicContact CG2-CD2 3.97Å; I9-F386 HydrophobicContact CG2-CE2 4.13Å; I363-F386 HydrophobicContact CD1-CE1 4.37Å; I363-F386 HydrophobicContact CG2-CE1 4.42Å; P382-F386 WeakPolarHBondContact O-CB 3.49Å; P382-F386 PolarHBondContact O-N 3.45Å; L383-F386 HydrophobicContact CD1-CD1 4.37Å; L383-F386 PolarHBondContact O-N 2.72Å; F386-N388 PolarHBondContact O-N 3.48Å; F386-S389 WeakPolarHBondContact O-CB 3.25Å; F386-S389 PolarHBondContact O-N 3.35Å; F386-Y390 WeakPolarHBondContact O-CB 3.07Å; F386-Y390 PolarHBondContact O-N 2.9Å
387	V	90.5	Very high	90.5	Very high	13 Å²	13	25.4 Å²	25.4	8%	0.079	13%	0.128	C	C	.	.	H	α-helix	trans	-62	-45.7	-177.9	165.4	0	0	0	0	111.5	I363 F364 V368 L383 I385 Y390 V391	I363-V387 HydrophobicContact CG2-CG2 4.08Å; F364-V387 HydrophobicContact CD1-CG1 4.27Å; F364-V387 HydrophobicContact CE1-CG1 3.26Å; F364-V387 HydrophobicContact CE2-CG1 4.02Å; F364-V387 HydrophobicContact CZ-CG1 3.1Å; V368-V387 HydrophobicContact CG2-CG2 4.04Å; L383-V387 HydrophobicContact CD1-CG2 4.39Å; L383-V387 WeakPolarHBondContact O-CB 3.47Å; L383-V387 VanDerWaalsContact O-CG2 3.23Å; L383-V387 WeakPolarHBondContact O-CG2 3.48Å; L383-V387 PolarHBondContact O-N 2.75Å; I385-V387 PolarHBondContact O-N 2.78Å; V387-Y390 PolarHBondContact O-N 3.38Å; V387-V391 WeakPolarHBondContact O-CB 3.19Å; V387-V391 WeakPolarHBondContact O-CG2 3.41Å; V387-V391 PolarHBondContact O-N 3.24Å
388	N	92.3	Very high	90.5	Very high	2 Å²	2	19.6 Å²	19.6	1%	0.011	10%	0.101	C	C	.	.	H	α-helix	trans	-67.5	-38.6	177.1	-75.3	-77.4	0	0	0	112	F46 Q95 I99 L221 G384 I385 F386 Y390 V391 I392	F46-N388 HydrophobicContact CE1-CB 3.78Å; F46-N388 HydrophobicContact CE2-CB 4.17Å; F46-N388 HydrophobicContact CZ-CB 3.48Å; F46-N388 VanDerWaalsContact CZ-CB 3.48Å; Q95-N388 PolarHBondContact NE2-OD1 2.91Å; I99-N388 WeakPolarHBondContact CD1-OD1 3.22Å; L221-N388 PolarHBondContact O-ND2 3.45Å; G384-N388 PolarHBondContact O-N 3.34Å; G384-N388 VanDerWaalsContact O-N 3.09Å; G384-N388 PolarHBondContact O-ND2 2.94Å; I385-N388 PolarHBondContact O-N 2.9Å; F386-N388 PolarHBondContact O-N 3.48Å; N388-Y390 VanDerWaalsContact C-N 3.35Å; N388-Y390 PolarHBondContact O-N 2.98Å; N388-V391 WeakPolarHBondContact O-CB 3.29Å; N388-V391 PolarHBondContact O-N 3.49Å; N388-I392 WeakPolarHBondContact O-CG1 3.33Å; N388-I392 PolarHBondContact O-N 2.64Å
389	S	94.1	Very high	90.8	Very high	12 Å²	12	15.3 Å²	15.3	8%	0.084	8%	0.081	C	C	.	.	H	α-helix	trans	-59.8	-46.6	175	-60	0	0	0	0	111.5	L45 F46 I385 F386 V391 I392 L393	L45-S389 WeakPolarHBondContact CD2-OG 3.4Å; F46-S389 WeakPolarHBondContact CE1-OG 3.43Å; I385-S389 VanDerWaalsContact O-CB 3.3Å; I385-S389 WeakPolarHBondContact O-CB 3.31Å; I385-S389 PolarHBondContact O-N 3.19Å; I385-S389 PolarHBondContact O-OG 2.87Å; F386-S389 WeakPolarHBondContact O-CB 3.25Å; F386-S389 PolarHBondContact O-N 3.35Å; S389-V391 VanDerWaalsContact C-N 3.33Å; S389-V391 PolarHBondContact O-N 3.38Å; S389-I392 PolarHBondContact O-N 3.46Å; S389-L393 WeakPolarHBondContact O-CB 3.19Å; S389-L393 PolarHBondContact O-N 2.91Å
390	Y	90.1	Very high	90.9	Very high	36 Å²	36	16.2 Å²	16.2	14%	0.141	9%	0.087	C	C	.	.	H	α-helix	trans	-58.5	-47.6	175.2	174.3	-98.5	0	0	0	111	A356 I359 R360 I363 F386 V387 N388 I392 L393 V394	A356-Y390 PolarHBondContact O-OH 2.98Å; I359-Y390 VanDerWaalsContact CB-OH 3.29Å; I359-Y390 WeakPolarHBondContact CB-OH 3.36Å; I359-Y390 HydrophobicContact CG2-CE2 4.02Å; I359-Y390 VanDerWaalsContact CG2-OH 3.23Å; I359-Y390 WeakPolarHBondContact CG2-OH 3.48Å; R360-Y390 HydrophobicContact CB-CE1 3.95Å; R360-Y390 HydrophobicContact CG-CE1 4.26Å; R360-Y390 PolarHBondContact N-OH 2.93Å; I363-Y390 HydrophobicContact CD1-CD1 3.87Å; I363-Y390 HydrophobicContact CD1-CD2 4.04Å; I363-Y390 HydrophobicContact CD1-CE1 3.8Å; I363-Y390 HydrophobicContact CD1-CE2 3.97Å; I363-Y390 HydrophobicContact CD1-CG 3.99Å; F386-Y390 WeakPolarHBondContact O-CB 3.07Å; F386-Y390 PolarHBondContact O-N 2.9Å; V387-Y390 PolarHBondContact O-N 3.38Å; N388-Y390 VanDerWaalsContact C-N 3.35Å; N388-Y390 PolarHBondContact O-N 2.98Å; Y390-I392 VanDerWaalsContact C-N 3.32Å; Y390-I392 PolarHBondContact O-N 3Å; Y390-L393 PolarHBondContact O-N 3.02Å; Y390-L393 VanDerWaalsContact O-N 3.17Å; Y390-V394 HydrophobicContact CD1-CG2 4.19Å; Y390-V394 HydrophobicContact CD2-CG2 4.44Å; Y390-V394 HydrophobicContact CE1-CG2 3.69Å; Y390-V394 HydrophobicContact CE2-CG2 3.98Å; Y390-V394 VanDerWaalsContact O-CG2 3.32Å; Y390-V394 WeakPolarHBondContact O-CG2 3.2Å; Y390-V394 PolarHBondContact O-N 3.33Å
391	V	90.9	Very high	90.7	Very high	6 Å²	6	15.1 Å²	15.1	4%	0.036	8%	0.082	C	C	.	.	H	α-helix	trans	-59.5	-40	179.1	164.3	0	0	0	0	112.4	Y91 F364 V387 N388 S389	Y91-V391 HydrophobicContact CE1-CG1 3.31Å; Y91-V391 WeakPolarHBondContact OH-CG1 3.19Å; F364-V391 HydrophobicContact CE2-CG2 4.18Å; F364-V391 HydrophobicContact CZ-CG2 4.16Å; V387-V391 WeakPolarHBondContact O-CB 3.19Å; V387-V391 WeakPolarHBondContact O-CG2 3.41Å; V387-V391 PolarHBondContact O-N 3.24Å; N388-V391 WeakPolarHBondContact O-CB 3.29Å; N388-V391 PolarHBondContact O-N 3.49Å; S389-V391 VanDerWaalsContact C-N 3.33Å; S389-V391 PolarHBondContact O-N 3.38Å
392	I	93.5	Very high	90.5	Very high	0 Å²	0	15.1 Å²	15.1	0%	0	8%	0.082	C	C	.	.	H	α-helix	trans	-67.5	-48.2	173.9	-64.7	160.3	0	0	0	110.1	F46 L49 L50 S53 L92 Q95 N388 S389 Y390 V394 C395	F46-I392 HydrophobicContact CB-CD1 4.24Å; F46-I392 HydrophobicContact CD1-CD1 4.11Å; F46-I392 HydrophobicContact CG-CD1 4.21Å; L49-I392 HydrophobicContact CB-CB 4.29Å; L49-I392 HydrophobicContact CB-CG2 3.65Å; L49-I392 WeakPolarHBondContact O-CG2 3.38Å; L50-I392 HydrophobicContact CD2-CD1 4.4Å; L50-I392 HydrophobicContact CD2-CG1 4.3Å; L50-I392 HydrophobicContact CD2-CG2 4.12Å; L50-I392 HydrophobicContact CG-CD1 4.18Å; L50-I392 HydrophobicContact CG-CG2 4.27Å; S53-I392 WeakPolarHBondContact OG-CG2 3.3Å; S53-I392 PolarHBondContact OG-O 3.26Å; L92-I392 HydrophobicContact CD2-CG2 4.13Å; Q95-I392 HydrophobicContact CB-CG1 4.43Å; Q95-I392 HydrophobicContact CG-CD1 4.37Å; Q95-I392 HydrophobicContact CG-CG1 3.89Å; N388-I392 WeakPolarHBondContact O-CG1 3.33Å; N388-I392 PolarHBondContact O-N 2.64Å; S389-I392 PolarHBondContact O-N 3.46Å; Y390-I392 VanDerWaalsContact C-N 3.32Å; Y390-I392 PolarHBondContact O-N 3Å; I392-V394 VanDerWaalsContact C-N 3.29Å; I392-V394 PolarHBondContact O-N 2.98Å; I392-C395 VanDerWaalsContact O-CB 3.31Å; I392-C395 WeakPolarHBondContact O-CB 3.47Å; I392-C395 PolarHBondContact O-N 3.41Å
393	L	91.4	Very high	90.4	Very high	73 Å²	73	15.3 Å²	15.3	38%	0.382	8%	0.082	S	C	.	.	H	α-helix	trans	-59.6	-36.4	-177.2	-175.7	66.1	0	0	0	112.9	L49 Y52 S389 Y390 C395 A396 V397	L49-L393 HydrophobicContact CD2-CD1 4.3Å; Y52-L393 HydrophobicContact CD1-CD1 4.48Å; Y52-L393 HydrophobicContact CE1-CD1 4.16Å; S389-L393 WeakPolarHBondContact O-CB 3.19Å; S389-L393 PolarHBondContact O-N 2.91Å; Y390-L393 PolarHBondContact O-N 3.02Å; Y390-L393 VanDerWaalsContact O-N 3.17Å; L393-C395 PolarHBondContact O-N 3.49Å; L393-C395 VanDerWaalsContact O-N 3.17Å; L393-A396 WeakPolarHBondContact O-CB 3.39Å; L393-A396 PolarHBondContact O-N 3.38Å; L393-V397 PolarHBondContact O-N 2.69Å; L393-V397 VanDerWaalsContact O-N 3.13Å
394	V	89.5	Confident	90.2	Very high	19 Å²	19	20.3 Å²	20.3	12%	0.115	11%	0.107	C	C	.	.	H	α-helix	trans	-57.1	-28.9	175.3	167.9	0	0	0	0	112.1	M161 A356 Y390 I392 A396 V397	M161-V394 HydrophobicContact CE-CG1 4.37Å; A356-V394 HydrophobicContact CB-CG1 4.13Å; A356-V394 HydrophobicContact CB-CG2 4.17Å; Y390-V394 HydrophobicContact CD1-CG2 4.19Å; Y390-V394 HydrophobicContact CD2-CG2 4.44Å; Y390-V394 HydrophobicContact CE1-CG2 3.69Å; Y390-V394 HydrophobicContact CE2-CG2 3.98Å; Y390-V394 VanDerWaalsContact O-CG2 3.32Å; Y390-V394 WeakPolarHBondContact O-CG2 3.2Å; Y390-V394 PolarHBondContact O-N 3.33Å; I392-V394 VanDerWaalsContact C-N 3.29Å; I392-V394 PolarHBondContact O-N 2.98Å; V394-A396 VanDerWaalsContact C-N 3.32Å; V394-A396 PolarHBondContact O-N 2.95Å; V394-V397 WeakPolarHBondContact O-CB 3.18Å
395	C	93.3	Very high	89.7	Confident	0 Å²	0	22.7 Å²	22.7	0%	0	12%	0.116	C	C	.	.	H	α-helix	trans	-75.2	-20.9	176.4	-59.9	0	0	0	0	113.2	N57 N88 Y91 L92 I392 L393	N57-C395 PolarHBondContact ND2-O 3.01Å; N88-C395 HydrophobicContact CB-CB 4.25Å; N88-C395 PolarHBondContact ND2-O 2.93Å; Y91-C395 WeakPolarHBondContact CD1-SG 3.37Å; L92-C395 HydrophobicContact CD2-CB 3.9Å; L92-C395 HydrophobicContact CG-CB 4.36Å; I392-C395 VanDerWaalsContact O-CB 3.31Å; I392-C395 WeakPolarHBondContact O-CB 3.47Å; I392-C395 PolarHBondContact O-N 3.41Å; L393-C395 PolarHBondContact O-N 3.49Å; L393-C395 VanDerWaalsContact O-N 3.17Å
396	A	92.4	Very high	89.3	Confident	0 Å²	0	22.5 Å²	22.5	0%	0	12%	0.115	C	C	.	.	H	α-helix	trans	-90.4	-26.3	177.6	0	0	0	0	0	112.7	Y52 L393 V394 L398 P399 T400	Y52-A396 HydrophobicContact CD1-CB 3.62Å; Y52-A396 HydrophobicContact CE1-CB 3.41Å; Y52-A396 VanDerWaalsContact CE1-CB 3.41Å; L393-A396 WeakPolarHBondContact O-CB 3.39Å; L393-A396 PolarHBondContact O-N 3.38Å; V394-A396 VanDerWaalsContact C-N 3.32Å; V394-A396 PolarHBondContact O-N 2.95Å; A396-L398 PolarHBondContact O-N 3.37Å; A396-P399 WeakPolarHBondContact O-CD 3.18Å; A396-T400 VanDerWaalsContact O-CB 3.27Å; A396-T400 WeakPolarHBondContact O-CB 3.32Å; A396-T400 PolarHBondContact O-N 2.87Å; A396-T400 PolarHBondContact O-OG1 3.17Å
397	V	88.2	Confident	89	Confident	19 Å²	19	25.4 Å²	25.4	12%	0.115	13%	0.128	C	C	.	.	H	α-helix	trans	-47.4	-54.1	-176.7	150.4	0	0	0	0	113	W352 L393 V394 T400 V401	W352-V397 HydrophobicContact CG-CG1 4.03Å; W352-V397 VanDerWaalsContact NE1-CG1 3.33Å; L393-V397 PolarHBondContact O-N 2.69Å; L393-V397 VanDerWaalsContact O-N 3.13Å; V394-V397 WeakPolarHBondContact O-CB 3.18Å; V397-T400 PolarHBondContact O-N 3.15Å; V397-V401 VanDerWaalsContact O-CG2 3.31Å; V397-V401 WeakPolarHBondContact O-CG2 3.37Å; V397-V401 PolarHBondContact O-N 3.03Å
398	L	88.1	Confident	88.6	Confident	4 Å²	4	26.9 Å²	26.9	2%	0.021	13%	0.134	C	C	.	.	H	α-helix	trans	-61.5	-55.3	-174.9	168.5	61.7	0	0	0	111.3	M60 L84 Q349 N353 A396 T400 H402	M60-L398 HydrophobicContact CE-CG 4.41Å; M60-L398 HydrophobicContact SD-CG 4.4Å; L84-L398 HydrophobicContact CB-CD2 3.93Å; L84-L398 HydrophobicContact CD1-CD2 3.78Å; L84-L398 HydrophobicContact CG-CD2 4.34Å; Q349-L398 HydrophobicContact CG-CD1 3.19Å; N353-L398 WeakPolarHBondContact ND2-CD1 2.97Å; N353-L398 WeakPolarHBondContact OD1-CB 3.28Å; A396-L398 PolarHBondContact O-N 3.37Å; L398-T400 VanDerWaalsContact C-N 3.35Å; L398-T400 PolarHBondContact O-N 3.43Å; L398-H402 WeakPolarHBondContact O-CB 3.07Å; L398-H402 PolarHBondContact O-N 2.89Å
399	P	90.7	Very high	88.3	Confident	0 Å²	0	26.8 Å²	26.8	0%	0	13%	0.134	C	C	.	.	H	α-helix	trans	-53.8	-46.4	170.7	-27.9	31.7	0	0	0	114.1	S56 N57 M60 A396 V401 H402 L403	S56-P399 WeakPolarHBondContact O-CB 3.29Å; N57-P399 HydrophobicContact CB-CG 4.22Å; N57-P399 VanDerWaalsContact CG-CG 3.46Å; N57-P399 VanDerWaalsContact OD1-CG 3.25Å; N57-P399 WeakPolarHBondContact OD1-CG 3.49Å; M60-P399 HydrophobicContact CB-CB 3.93Å; M60-P399 HydrophobicContact CB-CG 4.41Å; M60-P399 VanDerWaalsContact SD-CA 3.59Å; M60-P399 HydrophobicContact SD-CB 4.03Å; M60-P399 HydrophobicContact SD-CG 3.95Å; A396-P399 WeakPolarHBondContact O-CD 3.18Å; P399-V401 PolarHBondContact O-N 3.34Å; P399-H402 WeakPolarHBondContact O-CB 3.45Å; P399-H402 PolarHBondContact O-N 3.5Å; P399-L403 WeakPolarHBondContact O-CB 3.33Å; P399-L403 VanDerWaalsContact O-CG 3.24Å; P399-L403 WeakPolarHBondContact O-CG 3.47Å; P399-L403 PolarHBondContact O-N 3.39Å
400	T	90.3	Very high	87.8	Confident	26 Å²	26	31.3 Å²	31.3	16%	0.16	15%	0.153	C	C	.	.	H	α-helix	trans	-63.2	-46.7	-175.6	-66.1	0	0	0	0	111.5	Y52 A396 V397 L398 H402 L403 I404	Y52-T400 WeakPolarHBondContact OH-CG2 3.21Å; Y52-T400 PolarHBondContact OH-OG1 3.13Å; A396-T400 VanDerWaalsContact O-CB 3.27Å; A396-T400 WeakPolarHBondContact O-CB 3.32Å; A396-T400 PolarHBondContact O-N 2.87Å; A396-T400 PolarHBondContact O-OG1 3.17Å; V397-T400 PolarHBondContact O-N 3.15Å; L398-T400 VanDerWaalsContact C-N 3.35Å; L398-T400 PolarHBondContact O-N 3.43Å; T400-H402 VanDerWaalsContact C-N 3.29Å; T400-H402 PolarHBondContact O-N 2.99Å; T400-L403 PolarHBondContact O-N 3.28Å; T400-I404 HydrophobicContact CG2-CD1 3.63Å; T400-I404 HydrophobicContact CG2-CG1 4.38Å; T400-I404 WeakPolarHBondContact O-CB 3.4Å; T400-I404 VanDerWaalsContact O-CG1 3.23Å; T400-I404 WeakPolarHBondContact O-CG1 3.38Å; T400-I404 PolarHBondContact O-N 3.24Å
401	V	86	Confident	87.5	Confident	14 Å²	14	34.6 Å²	34.6	9%	0.085	17%	0.173	C	C	.	.	H	α-helix	trans	-62.2	-41.9	176.5	179.1	0	0	0	0	110	I348 Q349 W352 V397 P399 L403 I404 Y405	I348-V401 HydrophobicContact CG2-CG1 4.13Å; Q349-V401 HydrophobicContact CB-CB 4.31Å; Q349-V401 HydrophobicContact CB-CG1 3.71Å; Q349-V401 HydrophobicContact CG-CB 4.43Å; Q349-V401 HydrophobicContact CG-CG1 4.35Å; W352-V401 HydrophobicContact CG-CG2 4.43Å; V397-V401 VanDerWaalsContact O-CG2 3.31Å; V397-V401 WeakPolarHBondContact O-CG2 3.37Å; V397-V401 PolarHBondContact O-N 3.03Å; P399-V401 PolarHBondContact O-N 3.34Å; V401-L403 PolarHBondContact O-N 3.37Å; V401-I404 PolarHBondContact O-N 2.99Å; V401-Y405 HydrophobicContact CG1-CD2 3.6Å; V401-Y405 HydrophobicContact CG1-CE2 3.92Å; V401-Y405 WeakPolarHBondContact O-CD2 3.22Å; V401-Y405 PolarHBondContact O-N 3.44Å
402	H	86.1	Confident	87.2	Confident	3 Å²	3	35.5 Å²	35.5	1%	0.014	18%	0.178	C	C	.	.	H	α-helix	trans	-58	-47.9	175.9	-175.5	65.2	0	0	0	112.4	M60 Y73 Q349 L398 P399 T400 S406	M60-H402 HydrophobicContact CE-CB 4.18Å; M60-H402 HydrophobicContact SD-CB 4.36Å; Y73-H402 AromaticContact CE1-CE1 3.57Å; Y73-H402 AromaticContact CZ-CE1 3.68Å; Y73-H402 AromaticContact CZ-NE2 3.89Å; Y73-H402 PolarHBondContact OH-CE1 2.84Å; Y73-H402 PolarHBondContact OH-NE2 3.3Å; Q349-H402 PolarHBondContact OE1-ND1 3.2Å; L398-H402 WeakPolarHBondContact O-CB 3.07Å; L398-H402 PolarHBondContact O-N 2.89Å; P399-H402 WeakPolarHBondContact O-CB 3.45Å; P399-H402 PolarHBondContact O-N 3.5Å; T400-H402 VanDerWaalsContact C-N 3.29Å; T400-H402 PolarHBondContact O-N 2.99Å; H402-S406 WeakPolarHBondContact O-CB 2.97Å; H402-S406 PolarHBondContact O-N 2.81Å
403	L	87.5	Confident	86.9	Confident	26 Å²	26	36.6 Å²	36.6	14%	0.136	18%	0.183	C	C	.	.	H	α-helix	trans	-69.6	-32	-178.5	-65.6	-177	0	0	0	113.5	L59 A63 P399 T400 V401 A409 I413	L59-L403 HydrophobicContact CB-CD1 3.67Å; L59-L403 HydrophobicContact CD1-CD1 4.11Å; A63-L403 HydrophobicContact CB-CD2 4.48Å; P399-L403 WeakPolarHBondContact O-CB 3.33Å; P399-L403 VanDerWaalsContact O-CG 3.24Å; P399-L403 WeakPolarHBondContact O-CG 3.47Å; P399-L403 PolarHBondContact O-N 3.39Å; T400-L403 PolarHBondContact O-N 3.28Å; V401-L403 PolarHBondContact O-N 3.37Å; L403-A409 HydrophobicContact CD2-CB 4Å; L403-I413 HydrophobicContact CD1-CD1 4.16Å; L403-I413 HydrophobicContact CD2-CD1 3.27Å; L403-I413 HydrophobicContact CG-CD1 4.25Å
404	I	85.1	Confident	86.5	Confident	112 Å²	112	39.6 Å²	39.6	57%	0.574	19%	0.193	S	C	*	.	H	α-helix	trans	-71.5	-46.7	177.8	-71.2	169.3	0	0	0	110.6	T400 V401	T400-I404 HydrophobicContact CG2-CD1 3.63Å; T400-I404 HydrophobicContact CG2-CG1 4.38Å; T400-I404 WeakPolarHBondContact O-CB 3.4Å; T400-I404 VanDerWaalsContact O-CG1 3.23Å; T400-I404 WeakPolarHBondContact O-CG1 3.38Å; T400-I404 PolarHBondContact O-N 3.24Å; V401-I404 PolarHBondContact O-N 2.99Å
405	Y	82.9	Confident	86.3	Confident	53 Å²	53	44 Å²	44	21%	0.208	21%	0.212	C	C	.	.	H	α-helix	trans	-96.6	-20.6	-169.3	-70.2	-78.7	0	0	0	114.1	Y323 P345 I348 V401 K407	Y323-Y405 HydrophobicContact CD1-CD1 4.04Å; Y323-Y405 AromaticContact CD1-CE1 3.91Å; Y323-Y405 HydrophobicContact CD1-CE1 3.91Å; Y323-Y405 AromaticContact CE1-CD1 3.81Å; Y323-Y405 HydrophobicContact CE1-CD1 3.81Å; Y323-Y405 HydrophobicContact CE1-CE1 4.16Å; P345-Y405 VanDerWaalsContact CB-CB 3.46Å; P345-Y405 WeakPolarHBondContact CG-O 3.49Å; I348-Y405 HydrophobicContact CD1-CD1 4.47Å; I348-Y405 HydrophobicContact CD1-CE1 4.16Å; I348-Y405 HydrophobicContact CG2-CD2 4.48Å; I348-Y405 HydrophobicContact CG2-CE2 3.96Å; V401-Y405 HydrophobicContact CG1-CD2 3.6Å; V401-Y405 HydrophobicContact CG1-CE2 3.92Å; V401-Y405 WeakPolarHBondContact O-CD2 3.22Å; V401-Y405 PolarHBondContact O-N 3.44Å; Y405-K407 PolarHBondContact O-N 3.04Å
406	S	83.1	Confident	85.8	Confident	10 Å²	10	47.1 Å²	47.1	7%	0.07	23%	0.229	C	C	.	.			trans	-83.2	103.8	175.7	-179.6	0	0	0	0	111	Y73 H402 E408 A409 H410	Y73-S406 PolarHBondContact OH-OG 3.35Å; H402-S406 WeakPolarHBondContact O-CB 2.97Å; H402-S406 PolarHBondContact O-N 2.81Å; S406-E408 PolarHBondContact O-N 3.48Å; S406-A409 PolarHBondContact O-N 3.01Å; S406-A409 PolarHBondContact OG-N 3.22Å; S406-A409 VanDerWaalsContact OG-N 3.14Å; S406-H410 PolarHBondContact O-N 3.22Å
407	K	82.7	Confident	85.3	Confident	105 Å²	105	52.5 Å²	52.5	46%	0.457	26%	0.257	S	S	.	.	H	α-helix	trans	-54.7	-38.8	172.3	-72.7	-177.9	174.6	179	0	111.7	H341 Y405 H410 N411	H341-K407 PolarHBondContact CE1-NZ 2.88Å; H341-K407 PolarHBondContact NE2-NZ 3.16Å; Y405-K407 PolarHBondContact O-N 3.04Å; K407-H410 PolarHBondContact O-N 3.11Å; K407-N411 WeakPolarHBondContact O-CB 3.42Å; K407-N411 VanDerWaalsContact O-CG 3.23Å; K407-N411 PolarHBondContact O-N 3.04Å; K407-N411 PolarHBondContact O-ND2 3.45Å
408	E	82.7	Confident	85	Confident	44 Å²	44	57.2 Å²	57.2	21%	0.206	28%	0.276	C	S	.	.	H	α-helix	trans	-65.1	-48.2	178	-173.2	-178.8	165	0	0	111.3	N71 S72 Y73 S406 H410 N411 I412	N71-E408 WeakPolarHBondContact CA-OE1 3.43Å; S72-E408 VanDerWaalsContact CB-OE2 3.27Å; S72-E408 WeakPolarHBondContact CB-OE2 3.45Å; S72-E408 PolarHBondContact N-OE1 3.27Å; S72-E408 PolarHBondContact OG-OE2 3.49Å; Y73-E408 HydrophobicContact CE2-CG 4.38Å; S406-E408 PolarHBondContact O-N 3.48Å; E408-H410 VanDerWaalsContact C-N 3.27Å; E408-H410 PolarHBondContact O-N 3.19Å; E408-N411 PolarHBondContact O-N 3.45Å; E408-I412 HydrophobicContact CG-CD1 3.88Å; E408-I412 VanDerWaalsContact O-CG1 3.28Å; E408-I412 WeakPolarHBondContact O-CG1 3.35Å; E408-I412 PolarHBondContact O-N 3.48Å
409	A	84.7	Confident	84.5	Confident	0 Å²	0	61.5 Å²	61.5	0%	0	30%	0.297	C	S	.	.	H	α-helix	trans	-60.2	-40.6	176.6	0	0	0	0	0	111.3	A63 L403 S406 I412 I413	A63-A409 HydrophobicContact CB-CB 3.8Å; L403-A409 HydrophobicContact CD2-CB 4Å; S406-A409 PolarHBondContact O-N 3.01Å; S406-A409 PolarHBondContact OG-N 3.22Å; S406-A409 VanDerWaalsContact OG-N 3.14Å; A409-I412 PolarHBondContact O-N 3.09Å; A409-I413 WeakPolarHBondContact O-CB 3.07Å; A409-I413 VanDerWaalsContact O-CG1 3.31Å; A409-I413 WeakPolarHBondContact O-CG1 3.49Å; A409-I413 PolarHBondContact O-N 3.3Å
410	H	83.6	Confident	83.9	Confident	107 Å²	107	64.4 Å²	64.4	50%	0.495	32%	0.317	S	S	.	.	H	α-helix	trans	-61.3	-47.5	175.6	-162.6	127.3	0	0	0	111.4	S406 K407 E408 I412 I413 K414	S406-H410 PolarHBondContact O-N 3.22Å; K407-H410 PolarHBondContact O-N 3.11Å; E408-H410 VanDerWaalsContact C-N 3.27Å; E408-H410 PolarHBondContact O-N 3.19Å; H410-I412 PolarHBondContact O-N 3.31Å; H410-I413 PolarHBondContact O-N 2.7Å; H410-K414 WeakPolarHBondContact O-CB 3.27Å; H410-K414 PolarHBondContact O-N 3.13Å
411	N	85.8	Confident	83.3	Confident	106 Å²	106	69.1 Å²	69.1	57%	0.567	34%	0.336	S	S	*	.	H	α-helix	trans	-62.6	-43.4	179.6	-73.8	-16.1	0	0	0	111.8	K407 E408 K414 H415	K407-N411 WeakPolarHBondContact O-CB 3.42Å; K407-N411 VanDerWaalsContact O-CG 3.23Å; K407-N411 PolarHBondContact O-N 3.04Å; K407-N411 PolarHBondContact O-ND2 3.45Å; E408-N411 PolarHBondContact O-N 3.45Å; N411-K414 PolarHBondContact O-N 3.32Å; N411-H415 VanDerWaalsContact O-CB 3.29Å; N411-H415 WeakPolarHBondContact O-CB 2.71Å; N411-H415 PolarHBondContact O-N 3.02Å
412	I	84.6	Confident	82.8	Confident	25 Å²	25	71.9 Å²	71.9	13%	0.128	35%	0.35	C	S	.	.	H	α-helix	trans	-61.5	-48.9	176.7	-66.8	163.3	0	0	0	110.4	A63 C66 G67 E408 A409 H410 H415 L416	A63-I412 WeakPolarHBondContact O-CD1 3.34Å; C66-I412 HydrophobicContact CB-CG2 3.96Å; G67-I412 VanDerWaalsContact CA-CD1 3.49Å; E408-I412 HydrophobicContact CG-CD1 3.88Å; E408-I412 VanDerWaalsContact O-CG1 3.28Å; E408-I412 WeakPolarHBondContact O-CG1 3.35Å; E408-I412 PolarHBondContact O-N 3.48Å; A409-I412 PolarHBondContact O-N 3.09Å; H410-I412 PolarHBondContact O-N 3.31Å; I412-H415 PolarHBondContact O-N 3.28Å; I412-L416 HydrophobicContact CG2-CD1 3.85Å; I412-L416 HydrophobicContact CG2-CG 4.48Å; I412-L416 WeakPolarHBondContact O-CB 3.35Å; I412-L416 VanDerWaalsContact O-CG 3.32Å; I412-L416 WeakPolarHBondContact O-CG 3.29Å; I412-L416 PolarHBondContact O-N 2.96Å
413	I	85.2	Confident	82.3	Confident	23 Å²	23	75.8 Å²	75.8	12%	0.118	37%	0.373	C	S	.	.	H	α-helix	trans	-66	-42.6	-179.5	-71.1	170.6	0	0	0	111.2	L59 L403 A409 H410 H415 L416 L417	L59-I413 HydrophobicContact CB-CD1 4.08Å; L59-I413 HydrophobicContact CD2-CD1 4.3Å; L59-I413 HydrophobicContact CD2-CG1 4.44Å; L59-I413 HydrophobicContact CD2-CG2 4.39Å; L403-I413 HydrophobicContact CD1-CD1 4.16Å; L403-I413 HydrophobicContact CD2-CD1 3.27Å; L403-I413 HydrophobicContact CG-CD1 4.25Å; A409-I413 WeakPolarHBondContact O-CB 3.07Å; A409-I413 VanDerWaalsContact O-CG1 3.31Å; A409-I413 WeakPolarHBondContact O-CG1 3.49Å; A409-I413 PolarHBondContact O-N 3.3Å; H410-I413 PolarHBondContact O-N 2.7Å; I413-H415 VanDerWaalsContact C-N 3.32Å; I413-H415 PolarHBondContact O-N 3.06Å; I413-L416 PolarHBondContact O-N 2.98Å; I413-L417 HydrophobicContact CG2-CD1 3.71Å; I413-L417 HydrophobicContact CG2-CG 4.14Å; I413-L417 WeakPolarHBondContact O-CB 3.4Å; I413-L417 VanDerWaalsContact O-CG 3.32Å; I413-L417 WeakPolarHBondContact O-CG 3.4Å; I413-L417 PolarHBondContact O-N 3.05Å
414	K	85	Confident	81.7	Confident	136 Å²	136	83.3 Å²	83.3	59%	0.591	40%	0.4	S	S	*	.	H	α-helix	trans	-59.9	-44.8	176.3	-174.5	178.6	179.8	-178.3	0	110.8	H410 N411 F418	H410-K414 WeakPolarHBondContact O-CB 3.27Å; H410-K414 PolarHBondContact O-N 3.13Å; N411-K414 PolarHBondContact O-N 3.32Å; K414-F418 WeakPolarHBondContact O-CB 3.06Å; K414-F418 PolarHBondContact O-N 3.48Å
415	H	84.4	Confident	81.2	Confident	111 Å²	111	81.7 Å²	81.7	51%	0.514	39%	0.392	S	S	.	.	H	α-helix	trans	-62.7	-44.9	176.3	-176.5	-90.2	0	0	0	111.7	N411 I412 I413 F418 M419	N411-H415 VanDerWaalsContact O-CB 3.29Å; N411-H415 WeakPolarHBondContact O-CB 2.71Å; N411-H415 PolarHBondContact O-N 3.02Å; I412-H415 PolarHBondContact O-N 3.28Å; I413-H415 VanDerWaalsContact C-N 3.32Å; I413-H415 PolarHBondContact O-N 3.06Å; H415-F418 PolarHBondContact O-N 2.92Å; H415-M419 WeakPolarHBondContact O-CB 3.33Å; H415-M419 WeakPolarHBondContact O-CG 3.44Å; H415-M419 PolarHBondContact O-N 2.99Å
416	L	81.8	Confident	80.9	Confident	66 Å²	66	86.1 Å²	86.1	35%	0.346	41%	0.412	S	S	.	.	H	α-helix	trans	-66	-42.6	178.2	-73.2	169.9	0	0	0	113.1	I62 C66 I412 I413 M419 S420	I62-L416 HydrophobicContact CG2-CD1 3.23Å; C66-L416 HydrophobicContact CB-CD1 4.15Å; I412-L416 HydrophobicContact CG2-CD1 3.85Å; I412-L416 HydrophobicContact CG2-CG 4.48Å; I412-L416 WeakPolarHBondContact O-CB 3.35Å; I412-L416 VanDerWaalsContact O-CG 3.32Å; I412-L416 WeakPolarHBondContact O-CG 3.29Å; I412-L416 PolarHBondContact O-N 2.96Å; I413-L416 PolarHBondContact O-N 2.98Å; L416-M419 PolarHBondContact O-N 3.14Å; L416-S420 WeakPolarHBondContact O-CB 3.34Å; L416-S420 PolarHBondContact O-N 3.17Å
417	L	81.9	Confident	80.4	Confident	113 Å²	113	89.9 Å²	89.9	59%	0.592	43%	0.432	S	S	*	.	H	α-helix	trans	-64.2	-42.6	175.5	-74	174	0	0	0	111	I413 S420 F421	I413-L417 HydrophobicContact CG2-CD1 3.71Å; I413-L417 HydrophobicContact CG2-CG 4.14Å; I413-L417 WeakPolarHBondContact O-CB 3.4Å; I413-L417 VanDerWaalsContact O-CG 3.32Å; I413-L417 WeakPolarHBondContact O-CG 3.4Å; I413-L417 PolarHBondContact O-N 3.05Å; L417-S420 PolarHBondContact O-N 3.14Å; L417-F421 WeakPolarHBondContact O-CB 3.48Å; L417-F421 PolarHBondContact O-N 3.22Å
418	F	82.4	Confident	80	Confident	118 Å²	118	92 Å²	92	52%	0.518	44%	0.441	S	S	.	.	H	α-helix	trans	-62.8	-46.7	175.7	-176.8	-105.6	0	0	0	111.6	K414 H415 S420 F421 L422	K414-F418 WeakPolarHBondContact O-CB 3.06Å; K414-F418 PolarHBondContact O-N 3.48Å; H415-F418 PolarHBondContact O-N 2.92Å; F418-S420 PolarHBondContact O-N 3.26Å; F418-F421 WeakPolarHBondContact O-CB 3.18Å; F418-F421 PolarHBondContact O-N 3.32Å; F418-L422 HydrophobicContact CD1-CD1 3.81Å; F418-L422 HydrophobicContact CD1-CG 4.32Å; F418-L422 HydrophobicContact CE1-CD1 3.29Å; F418-L422 HydrophobicContact CE1-CG 4Å; F418-L422 HydrophobicContact CE2-CG 4.44Å; F418-L422 HydrophobicContact CZ-CD1 3.71Å; F418-L422 HydrophobicContact CZ-CD2 4.24Å; F418-L422 HydrophobicContact CZ-CG 4.06Å; F418-L422 WeakPolarHBondContact O-CG 3.35Å; F418-L422 PolarHBondContact O-N 2.97Å
419	M	78	Confident	79.7	Confident	94 Å²	94	94.6 Å²	94.6	46%	0.463	46%	0.455	S	S	.	.	H	α-helix	trans	-62	-43.2	175.8	-73.2	-64.7	-108.4	0	0	111.8	H415 L416 F421 L422 V423	H415-M419 WeakPolarHBondContact O-CB 3.33Å; H415-M419 WeakPolarHBondContact O-CG 3.44Å; H415-M419 PolarHBondContact O-N 2.99Å; L416-M419 PolarHBondContact O-N 3.14Å; M419-F421 VanDerWaalsContact C-N 3.3Å; M419-F421 PolarHBondContact O-N 3.24Å; M419-L422 PolarHBondContact O-N 3.08Å; M419-V423 VanDerWaalsContact O-CG2 3.31Å; M419-V423 WeakPolarHBondContact O-CG2 3.38Å; M419-V423 PolarHBondContact O-N 3.07Å
420	S	78.1	Confident	78.9	Confident	60 Å²	60	98 Å²	98	42%	0.42	48%	0.476	S	S	.	.	H	α-helix	trans	-63.6	-36.3	175.5	-177.7	0	0	0	0	112.3	L416 L417 F418 R424	L416-S420 WeakPolarHBondContact O-CB 3.34Å; L416-S420 PolarHBondContact O-N 3.17Å; L417-S420 PolarHBondContact O-N 3.14Å; F418-S420 PolarHBondContact O-N 3.26Å; S420-R424 WeakPolarHBondContact O-CG 3.48Å; S420-R424 PolarHBondContact O-N 3.16Å; S420-R424 VanDerWaalsContact O-N 3.16Å
421	F	77.3	Confident	78.3	Confident	126 Å²	126	97.3 Å²	97.3	55%	0.553	48%	0.475	S	S	*	.	H	α-helix	trans	-68	-45.6	175.8	-179.5	-100.8	0	0	0	111.2	L417 F418 M419 V423 R424 L425	L417-F421 WeakPolarHBondContact O-CB 3.48Å; L417-F421 PolarHBondContact O-N 3.22Å; F418-F421 WeakPolarHBondContact O-CB 3.18Å; F418-F421 PolarHBondContact O-N 3.32Å; M419-F421 VanDerWaalsContact C-N 3.3Å; M419-F421 PolarHBondContact O-N 3.24Å; F421-V423 PolarHBondContact O-N 2.96Å; F421-R424 PolarHBondContact O-N 3.02Å; F421-L425 HydrophobicContact CD1-CD1 4.48Å; F421-L425 HydrophobicContact CE1-CD1 3.69Å; F421-L425 HydrophobicContact CE2-CD1 4.32Å; F421-L425 HydrophobicContact CZ-CD1 3.59Å; F421-L425 WeakPolarHBondContact O-CB 3.28Å; F421-L425 PolarHBondContact O-N 2.77Å
422	L	75.8	Confident	77.6	Confident	72 Å²	72	96.9 Å²	96.9	38%	0.377	47%	0.473	S	S	.	.	H	α-helix	trans	-62.1	-42.2	176.7	-73.9	-178	0	0	0	112.8	F418 M419 R424 L425 K426	F418-L422 HydrophobicContact CD1-CD1 3.81Å; F418-L422 HydrophobicContact CD1-CG 4.32Å; F418-L422 HydrophobicContact CE1-CD1 3.29Å; F418-L422 HydrophobicContact CE1-CG 4Å; F418-L422 HydrophobicContact CE2-CG 4.44Å; F418-L422 HydrophobicContact CZ-CD1 3.71Å; F418-L422 HydrophobicContact CZ-CD2 4.24Å; F418-L422 HydrophobicContact CZ-CG 4.06Å; F418-L422 WeakPolarHBondContact O-CG 3.35Å; F418-L422 PolarHBondContact O-N 2.97Å; M419-L422 PolarHBondContact O-N 3.08Å; L422-R424 VanDerWaalsContact C-N 3.33Å; L422-R424 PolarHBondContact O-N 2.98Å; L422-L425 PolarHBondContact O-N 3.09Å; L422-K426 WeakPolarHBondContact O-CB 3.34Å; L422-K426 PolarHBondContact O-N 3.42Å
423	V	75.6	Confident	76.6	Confident	84 Å²	84	99.8 Å²	99.8	51%	0.509	49%	0.492	S	S	.	.	H	α-helix	trans	-62.5	-42	175.8	171.1	0	0	0	0	110.9	M419 F421 K426 N427	M419-V423 VanDerWaalsContact O-CG2 3.31Å; M419-V423 WeakPolarHBondContact O-CG2 3.38Å; M419-V423 PolarHBondContact O-N 3.07Å; F421-V423 PolarHBondContact O-N 2.96Å; V423-K426 PolarHBondContact O-N 3.34Å; V423-N427 VanDerWaalsContact O-CG 3.32Å; V423-N427 PolarHBondContact O-N 3.13Å; V423-N427 PolarHBondContact O-OD1 3.48Å
424	R	75	Confident	75.6	Confident	184 Å²	184	104.9 Å²	104.9	69%	0.694	52%	0.515	S	S	*	.	H	α-helix	trans	-64.3	-40	174.2	-78.3	-178.7	179.7	-177	0.9	112.3	S420 F421 L422 N427 K428	S420-R424 WeakPolarHBondContact O-CG 3.48Å; S420-R424 PolarHBondContact O-N 3.16Å; S420-R424 VanDerWaalsContact O-N 3.16Å; F421-R424 PolarHBondContact O-N 3.02Å; L422-R424 VanDerWaalsContact C-N 3.33Å; L422-R424 PolarHBondContact O-N 2.98Å; R424-N427 PolarHBondContact O-N 2.66Å; R424-K428 WeakPolarHBondContact O-CB 3.34Å; R424-K428 PolarHBondContact O-N 2.96Å
425	L	74.2	Confident	74.8	Confident	78 Å²	78	103.9 Å²	103.9	41%	0.408	51%	0.512	S	S	.	.	H	α-helix	trans	-65.4	-44.5	177.9	-143.8	106.8	0	0	0	110.9	F421 L422 K428 I429	F421-L425 HydrophobicContact CD1-CD1 4.48Å; F421-L425 HydrophobicContact CE1-CD1 3.69Å; F421-L425 HydrophobicContact CE2-CD1 4.32Å; F421-L425 HydrophobicContact CZ-CD1 3.59Å; F421-L425 WeakPolarHBondContact O-CB 3.28Å; F421-L425 PolarHBondContact O-N 2.77Å; L422-L425 PolarHBondContact O-N 3.09Å; L425-K428 PolarHBondContact O-N 3.44Å; L425-I429 HydrophobicContact CD2-CD1 4Å; L425-I429 WeakPolarHBondContact O-CG1 3.41Å; L425-I429 PolarHBondContact O-N 2.93Å
426	K	76.1	Confident	73.8	Confident	146 Å²	146	103.8 Å²	103.8	64%	0.635	52%	0.515	S	S	*	.	H	α-helix	trans	-57.5	-50.9	175.1	-174.2	178.7	178.6	-178.6	0	110.8	L422 V423 K428 I429 T430	L422-K426 WeakPolarHBondContact O-CB 3.34Å; L422-K426 PolarHBondContact O-N 3.42Å; V423-K426 PolarHBondContact O-N 3.34Å; K426-K428 VanDerWaalsContact C-N 3.3Å; K426-K428 PolarHBondContact O-N 3.16Å; K426-I429 PolarHBondContact O-N 2.69Å; K426-T430 PolarHBondContact O-N 3.26Å; K426-T430 PolarHBondContact O-OG1 2.95Å
427	N	73.1	Confident	73	Confident	90 Å²	90	109.6 Å²	109.6	48%	0.481	53%	0.533	S	S	.	.	H	α-helix	trans	-62.1	-37.3	178.9	-70.2	-1.3	0	0	0	112.3	V423 R424 T430 I431	V423-N427 VanDerWaalsContact O-CG 3.32Å; V423-N427 PolarHBondContact O-N 3.13Å; V423-N427 PolarHBondContact O-OD1 3.48Å; R424-N427 PolarHBondContact O-N 2.66Å; N427-T430 PolarHBondContact O-N 3.24Å; N427-I431 WeakPolarHBondContact O-CD1 3.49Å; N427-I431 VanDerWaalsContact O-CG1 3.27Å; N427-I431 WeakPolarHBondContact O-CG1 3.4Å; N427-I431 PolarHBondContact O-N 3.12Å
428	K	75.7	Confident	72.6	Confident	149 Å²	149	110 Å²	110	65%	0.648	53%	0.534	S	S	*	.	H	α-helix	trans	-67.6	-38.3	176.6	-165.5	175.2	-176.5	-177.4	0	112.3	R424 L425 K426 N432	R424-K428 WeakPolarHBondContact O-CB 3.34Å; R424-K428 PolarHBondContact O-N 2.96Å; L425-K428 PolarHBondContact O-N 3.44Å; K426-K428 VanDerWaalsContact C-N 3.3Å; K426-K428 PolarHBondContact O-N 3.16Å; K428-N432 PolarHBondContact O-N 3.17Å; K428-N432 VanDerWaalsContact O-N 3.16Å
429	I	75.2	Confident	71.7	Confident	99 Å²	99	111.5 Å²	111.5	51%	0.508	55%	0.547	S	S	.	.	H	α-helix	trans	-67.6	-43.2	174.9	-67.1	166.2	0	0	0	110.4	L425 K426 I431 N432 V433	L425-I429 HydrophobicContact CD2-CD1 4Å; L425-I429 WeakPolarHBondContact O-CG1 3.41Å; L425-I429 PolarHBondContact O-N 2.93Å; K426-I429 PolarHBondContact O-N 2.69Å; I429-I431 PolarHBondContact O-N 2.88Å; I429-N432 PolarHBondContact O-N 3.06Å; I429-V433 WeakPolarHBondContact O-CG2 3.47Å; I429-V433 PolarHBondContact O-N 3.4Å
430	T	68.9	Low	71.5	Confident	71 Å²	71	113.4 Å²	113.4	44%	0.436	56%	0.557	S	S	.	*	H	α-helix	trans	-62.9	-42.3	179	-48.6	0	0	0	0	112.2	K426 N427 N432 V433 E434	K426-T430 PolarHBondContact O-N 3.26Å; K426-T430 PolarHBondContact O-OG1 2.95Å; N427-T430 PolarHBondContact O-N 3.24Å; T430-N432 VanDerWaalsContact C-N 3.33Å; T430-N432 PolarHBondContact O-N 2.99Å; T430-V433 PolarHBondContact O-N 3.02Å; T430-E434 PolarHBondContact O-N 3.02Å
431	I	71.2	Confident	71.1	Confident	93 Å²	93	116.2 Å²	116.2	48%	0.477	58%	0.577	S	S	.	*	H	α-helix	trans	-62.3	-40.8	175.1	-67.5	164.9	0	0	0	111.1	N427 I429 V433 E434 Q435	N427-I431 WeakPolarHBondContact O-CD1 3.49Å; N427-I431 VanDerWaalsContact O-CG1 3.27Å; N427-I431 WeakPolarHBondContact O-CG1 3.4Å; N427-I431 PolarHBondContact O-N 3.12Å; I429-I431 PolarHBondContact O-N 2.88Å; I431-V433 VanDerWaalsContact C-N 3.31Å; I431-V433 PolarHBondContact O-N 3.49Å; I431-E434 PolarHBondContact O-N 3.22Å; I431-Q435 HydrophobicContact CG2-CG 4.45Å; I431-Q435 WeakPolarHBondContact O-CB 2.97Å; I431-Q435 WeakPolarHBondContact O-CG 3.25Å; I431-Q435 PolarHBondContact O-N 3.25Å
432	N	69.8	Low	70.8	Confident	96 Å²	96	115.7 Å²	115.7	51%	0.513	58%	0.578	S	S	.	*	H	α-helix	trans	-63.9	-36.1	176.3	-83.3	8.2	0	0	0	112.2	K428 I429 T430 L436	K428-N432 PolarHBondContact O-N 3.17Å; K428-N432 VanDerWaalsContact O-N 3.16Å; I429-N432 PolarHBondContact O-N 3.06Å; T430-N432 VanDerWaalsContact C-N 3.33Å; T430-N432 PolarHBondContact O-N 2.99Å; N432-L436 WeakPolarHBondContact O-CB 3.26Å; N432-L436 PolarHBondContact O-N 3.04Å
433	V	64	Low	70.5	Confident	87 Å²	87	118 Å²	118	53%	0.527	59%	0.589	S	S	.	*	H	α-helix	trans	-69.1	-42.8	177.5	174.5	0	0	0	0	111.4	I429 T430 I431 L436 W437	I429-V433 WeakPolarHBondContact O-CG2 3.47Å; I429-V433 PolarHBondContact O-N 3.4Å; T430-V433 PolarHBondContact O-N 3.02Å; I431-V433 VanDerWaalsContact C-N 3.31Å; I431-V433 PolarHBondContact O-N 3.49Å; V433-L436 PolarHBondContact O-N 3.21Å; V433-W437 PolarHBondContact O-N 3.48Å
434	E	65.1	Low	70.2	Confident	129 Å²	129	119.9 Å²	119.9	60%	0.603	59%	0.593	S	S	*	*	H	α-helix	trans	-64	-42.6	174.9	-78.9	-176.4	163.5	0	0	112	T430 I431 L436 W437 I438	T430-E434 PolarHBondContact O-N 3.02Å; I431-E434 PolarHBondContact O-N 3.22Å; E434-L436 VanDerWaalsContact C-N 3.34Å; E434-L436 PolarHBondContact O-N 3.4Å; E434-W437 PolarHBondContact O-N 3.25Å; E434-I438 WeakPolarHBondContact O-CG1 3.47Å; E434-I438 PolarHBondContact O-N 2.97Å
435	Q	67.3	Low	70	Confident	116 Å²	116	116.1 Å²	116.1	54%	0.542	59%	0.587	S	S	.	*	H	α-helix	trans	-64.5	-37.8	175.4	-75.3	-166.8	-24.7	0	0	112.5	I431 W437 I438 L439	I431-Q435 HydrophobicContact CG2-CG 4.45Å; I431-Q435 WeakPolarHBondContact O-CB 2.97Å; I431-Q435 WeakPolarHBondContact O-CG 3.25Å; I431-Q435 PolarHBondContact O-N 3.25Å; Q435-W437 VanDerWaalsContact C-N 3.31Å; Q435-I438 PolarHBondContact O-N 3.05Å; Q435-L439 PolarHBondContact O-N 3.24Å; Q435-L439 VanDerWaalsContact O-N 3.07Å
436	L	64	Low	69.7	Low	109 Å²	109	118.5 Å²	118.5	57%	0.571	60%	0.598	S	S	*	*	H	α-helix	trans	-65.1	-38	174.8	-152.1	87.2	0	0	0	111.1	N432 V433 E434 L439 I440	N432-L436 WeakPolarHBondContact O-CB 3.26Å; N432-L436 PolarHBondContact O-N 3.04Å; V433-L436 PolarHBondContact O-N 3.21Å; E434-L436 VanDerWaalsContact C-N 3.34Å; E434-L436 PolarHBondContact O-N 3.4Å; L436-L439 PolarHBondContact O-N 3.03Å; L436-I440 HydrophobicContact CD2-CD1 4.08Å; L436-I440 HydrophobicContact CG-CD1 4.14Å; L436-I440 VanDerWaalsContact O-CG1 3.26Å; L436-I440 WeakPolarHBondContact O-CG1 3.35Å; L436-I440 PolarHBondContact O-N 3.21Å
437	W	64.4	Low	69.3	Low	188 Å²	188	116.7 Å²	116.7	71%	0.712	60%	0.596	S	S	*	*	H	α-helix	trans	-65	-40.8	177.2	-138.4	91	0	0	0	111.7	V433 E434 Q435 L439 I440 S441	V433-W437 PolarHBondContact O-N 3.48Å; E434-W437 PolarHBondContact O-N 3.25Å; Q435-W437 VanDerWaalsContact C-N 3.31Å; W437-L439 VanDerWaalsContact C-N 3.28Å; W437-L439 PolarHBondContact O-N 3.42Å; W437-I440 PolarHBondContact O-N 3.01Å; W437-S441 WeakPolarHBondContact O-CB 3.49Å; W437-S441 PolarHBondContact O-N 3.27Å; W437-S441 PolarHBondContact O-OG 2.98Å
438	I	73.2	Confident	69	Low	122 Å²	122	118.6 Å²	118.6	63%	0.626	60%	0.604	S	S	*	*	H	α-helix	trans	-65.7	-29.5	173.9	-66.1	167	0	0	0	112.2	E434 Q435 S441	E434-I438 WeakPolarHBondContact O-CG1 3.47Å; E434-I438 PolarHBondContact O-N 2.97Å; Q435-I438 PolarHBondContact O-N 3.05Å; I438-S441 WeakPolarHBondContact CA-OG 3.11Å; I438-S441 PolarHBondContact O-OG 3.07Å; I438-S441 VanDerWaalsContact O-OXT 3.07Å
439	L	62.9	Low	68.5	Low	149 Å²	149	116.2 Å²	116.2	78%	0.78	60%	0.601	S	S	*	*	H	α-helix	trans	-79.5	-23.3	176.5	-110.1	142.4	0	0	0	113.2	Q435 L436 W437	Q435-L439 PolarHBondContact O-N 3.24Å; Q435-L439 VanDerWaalsContact O-N 3.07Å; L436-L439 PolarHBondContact O-N 3.03Å; W437-L439 VanDerWaalsContact C-N 3.28Å; W437-L439 PolarHBondContact O-N 3.42Å
440	I	73.9	Confident	67.9	Low	133 Å²	133	117.7 Å²	117.7	68%	0.682	61%	0.608	S	S	*	*	H	α-helix	trans	-89.6	-29.4	178.5	-68.1	166.9	0	0	0	111.2	L436 W437	L436-I440 HydrophobicContact CD2-CD1 4.08Å; L436-I440 HydrophobicContact CG-CD1 4.14Å; L436-I440 VanDerWaalsContact O-CG1 3.26Å; L436-I440 WeakPolarHBondContact O-CG1 3.35Å; L436-I440 PolarHBondContact O-N 3.21Å; W437-I440 PolarHBondContact O-N 3.01Å
441	S	70.5	Confident	67.8	Low	119 Å²	119	121.9 Å²	121.9	83%	0.832	62%	0.624	S	S	*	*			trans	-80	0	173	68.1	0	0	0	0	112.2	W437 I438	W437-S441 WeakPolarHBondContact O-CB 3.49Å; W437-S441 PolarHBondContact O-N 3.27Å; W437-S441 PolarHBondContact O-OG 2.98Å; I438-S441 WeakPolarHBondContact CA-OG 3.11Å; I438-S441 PolarHBondContact O-OG 3.07Å; I438-S441 VanDerWaalsContact O-OXT 3.07Å

Retrieved 441 of 441 residues in 834.3 ms (Link to these results)

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