A0A059T9V8_HUMAN Loading...

Atypical chemokine receptor 1

Atypical chemokine receptor that controls chemokine levels and localization via high-affinity chemokine binding that is uncoupled from classic ligand-driven signal transduction cascades, resulting instead in chemokine sequestration, degradation, or transcytosis. Also known as interceptor (internalizing receptor) or chemokine-scavenging receptor or chemokine decoy receptor. Has a promiscuous chemokine-binding profile, interacting with inflammatory chemokines of both the CXC and the CC subfamilies but not with homeostatic chemokines. Acts as a receptor for chemokines including CCL2, CCL5, CCL7, CCL11, CCL13, CCL14, CCL17, CXCL5, CXCL6, IL8/CXCL8, CXCL11, GRO, RANTES, MCP-1 and TARC. May regulate chemokine bioavailability and, consequently, leukocyte recruitment through two distinct mechanisms: when expressed in endothelial cells, it sustains the abluminal to luminal transcytosis of tissue-derived chemokines and their subsequent presentation to circulating leukocytes; when expressed in erythrocytes, serves as blood reservoir of cognate chemokines but also as a chemokine sink, buffering potential surges in plasma chemokine levels.

AlphaFold DB , UniProt , Accession A0A059T9V8, Species HUMAN (Homo sapiens, Human), Gene DARC, Length 242 aa.

Structure Viewer

Loading PAE data...

(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	33.4	Very low	38	Very low	252 Å²	252	133 Å²	133	100%	1.241	73%	0.727	S	S	*	*				0	83	0	-72.6	173.6	166.9	0	0	106.8
2	G	38.6	Very low	37.8	Very low	73 Å²	73	132.4 Å²	132.4	75%	0.753	73%	0.734	S	S	*	*			trans	-84.8	124	176.9	0	0	0	0	0	108.5
3	N	41.7	Very low	37.2	Very low	146 Å²	146	131.1 Å²	131.1	78%	0.781	74%	0.74	S	S	*	*			trans	-72.3	134.2	170	-155.4	29.2	0	0	0	107.6
4	C	51.3	Low	36.7	Very low	63 Å²	63	131.1 Å²	131.1	43%	0.426	75%	0.745	S	S	.	*			trans	-126.5	112.7	-158.5	-157.8	0	0	0	0	105.4	C51	C4-C51 WeakPolarHBondContact CA-SG 3.21Å; C4-C51 HydrophobicContact CB-CB 4.23Å; C4-C51 WeakPolarHBondContact CB-SG 3.3Å; C4-C51 PolarHBondContact O-SG 3.44Å; C4-C51 WeakPolarHBondContact SG-CA 3.5Å; C4-C51 WeakPolarHBondContact SG-CB 3.23Å; C4-C51 CovalentContact SG-SG 2.02Å; C4-C51 PolarHBondContact SG-SG 2.8Å
5	L	41.3	Very low	36.1	Very low	89 Å²	89	133.9 Å²	133.9	47%	0.466	75%	0.749	S	S	.	*			trans	-84.5	125.6	-175.3	-70.8	168.7	0	0	0	110.3	R7 L45 A48	L5-R7 PolarHBondContact O-N 2.83Å; L5-L45 HydrophobicContact CD1-CD2 3.51Å; L5-A48 HydrophobicContact CD1-CB 4.24Å
6	H	40.8	Very low	35.6	Very low	126 Å²	126	135.1 Å²	135.1	58%	0.583	75%	0.753	S	S	*	*			trans	-65.1	131.2	166.4	-83.9	-55.2	0	0	0	109.2	A8 Y199	H6-A8 PolarHBondContact O-N 3.14Å; H6-Y199 HydrophobicContact CB-CD1 4.27Å; H6-Y199 HydrophobicContact CB-CE1 4.3Å; H6-Y199 AromaticContact CD2-CE1 3.97Å; H6-Y199 AromaticContact CD2-CZ 3.97Å
7	R	40.8	Very low	35.5	Very low	222 Å²	222	134.6 Å²	134.6	84%	0.838	76%	0.761	S	S	*	*			trans	-59.6	108.7	170.2	-167	176.4	-163.2	99.7	1	107.5	L5 E9	L5-R7 PolarHBondContact O-N 2.83Å; R7-E9 PolarHBondContact O-N 3.45Å; R7-E9 VanDerWaalsContact O-N 3.16Å
8	A	37.5	Very low	35.1	Very low	76 Å²	76	131.7 Å²	131.7	63%	0.628	75%	0.751	S	S	*	*			trans	-67	108.9	162.7	0	0	0	0	0	106.1	H6 L10	H6-A8 PolarHBondContact O-N 3.14Å; A8-L10 PolarHBondContact O-N 3.04Å
9	E	34.8	Very low	35.3	Very low	147 Å²	147	134.8 Å²	134.8	69%	0.687	76%	0.758	S	S	*	*			trans	-64	103.9	167.1	-72.8	-166.6	162.8	0	0	107.1	R7 S11	R7-E9 PolarHBondContact O-N 3.45Å; R7-E9 VanDerWaalsContact O-N 3.16Å; E9-S11 PolarHBondContact O-N 3.42Å
10	L	31	Very low	35	Very low	165 Å²	165	135.3 Å²	135.3	86%	0.864	76%	0.758	S	S	*	*			trans	-59.6	124.1	160.6	-102.8	79.3	0	0	0	107	A8	A8-L10 PolarHBondContact O-N 3.04Å
11	S	27.1	Very low	34.6	Very low	104 Å²	104	135.3 Å²	135.3	73%	0.727	76%	0.757	S	S	*	*			trans	-47.2	142.8	169.7	-59.1	0	0	0	0	111.1	E9 S13	E9-S11 PolarHBondContact O-N 3.42Å; S11-S13 PolarHBondContact O-N 3.04Å
12	P	35.1	Very low	34.5	Very low	126 Å²	126	133.4 Å²	133.4	82%	0.818	74%	0.742	S	S	*	*			trans	-73.3	100.9	177.4	30	-29.8	0	0	0	108.1	T14	P12-T14 PolarHBondContact O-N 3.36Å; P12-T14 VanDerWaalsContact O-N 3.15Å
13	S	30.3	Very low	34.4	Very low	115 Å²	115	138.4 Å²	138.4	80%	0.804	75%	0.746	S	S	*	*			trans	-71	104.4	160.1	53.8	0	0	0	0	107.2	S11 E15	S11-S13 PolarHBondContact O-N 3.04Å; S13-E15 PolarHBondContact O-N 3.42Å; S13-E15 VanDerWaalsContact O-N 3.14Å
14	T	30.5	Very low	33.9	Very low	132 Å²	132	138.4 Å²	138.4	81%	0.81	75%	0.746	S	S	*	*			trans	-54.2	111.3	162	-57.4	0	0	0	0	108.5	P12	P12-T14 PolarHBondContact O-N 3.36Å; P12-T14 VanDerWaalsContact O-N 3.15Å
15	E	27.6	Very low	33.2	Very low	173 Å²	173	142.4 Å²	142.4	81%	0.808	77%	0.767	S	S	*	*			trans	-171	120.4	134.2	-104.4	175.5	-179.7	0	0	112.1	S13	S13-E15 PolarHBondContact O-N 3.42Å; S13-E15 VanDerWaalsContact O-N 3.14Å
16	N	27.9	Very low	32.9	Very low	153 Å²	153	149.8 Å²	149.8	82%	0.818	79%	0.789	S	S	*	*			trans	36.8	120.5	155	-71.1	-22.4	0	0	0	122.2	S18	N16-S18 PolarHBondContact O-N 3.3Å
17	S	34.6	Very low	32.4	Very low	127 Å²	127	151.2 Å²	151.2	89%	0.888	80%	0.801	S	S	*	*			trans	-31.6	110.5	155.4	-170.8	0	0	0	0	115.2
18	S	27.4	Very low	31.8	Very low	82 Å²	82	146 Å²	146	57%	0.573	80%	0.799	S	S	*	*			trans	-145.8	118.7	138.9	57.1	0	0	0	0	108.4	N16 L20	N16-S18 PolarHBondContact O-N 3.3Å; S18-L20 PolarHBondContact O-N 2.84Å; S18-L20 VanDerWaalsContact O-N 3.1Å
19	Q	40.2	Very low	31.4	Very low	190 Å²	190	146.8 Å²	146.8	89%	0.888	80%	0.8	S	S	*	*			trans	-49.9	110.8	164.6	-178.1	178.9	2	0	0	108.2
20	L	27.9	Very low	31.2	Very low	145 Å²	145	151 Å²	151	76%	0.759	81%	0.811	S	S	*	*			trans	-129.5	116	176.5	-70.5	176.5	0	0	0	109.1	S18	S18-L20 PolarHBondContact O-N 2.84Å; S18-L20 VanDerWaalsContact O-N 3.1Å
21	D	27.6	Very low	31	Very low	136 Å²	136	146.4 Å²	146.4	73%	0.727	80%	0.804	S	S	*	*			trans	-56.4	138.6	177.2	-82.2	-47.4	0	0	0	111.6	E23	D21-E23 PolarHBondContact O-N 2.85Å
22	F	30.9	Very low	31	Very low	211 Å²	211	148.2 Å²	148.2	93%	0.925	81%	0.81	S	S	*	*	T	Hydrogen-bonded Turn	trans	-78.7	24.1	-173.9	-134	-92.9	0	0	0	113.4
23	E	36.7	Very low	30.8	Very low	179 Å²	179	149.4 Å²	149.4	84%	0.836	81%	0.81	S	S	*	*	T	Hydrogen-bonded Turn	trans	-109.9	-12.3	-178.9	-75.2	-148.8	120.4	0	0	114.8	D21	D21-E23 PolarHBondContact O-N 2.85Å
24	D	31.1	Very low	30.7	Very low	146 Å²	146	150.8 Å²	150.8	78%	0.781	81%	0.808	S	S	*	*	G	3₁₀ helix	trans	-99.6	5.4	-169.5	-83	-26.4	0	0	0	116.4
25	V	35.4	Very low	31	Very low	146 Å²	146	149.8 Å²	149.8	89%	0.885	81%	0.806	S	S	*	*	G	3₁₀ helix	trans	-92.2	-0.7	-178.6	-176.1	0	0	0	0	113.4
26	W	36.3	Very low	31.2	Very low	244 Å²	244	150.7 Å²	150.7	92%	0.924	81%	0.808	S	S	*	*	G	3₁₀ helix	trans	-88.7	-3	-178.5	-166.1	-100.1	0	0	0	115.4
27	N	31	Very low	31.5	Very low	156 Å²	156	149 Å²	149	83%	0.834	81%	0.806	S	S	*	*			trans	-117.6	78.3	-173.3	-156.5	22.8	0	0	0	114.6
28	S	26.6	Very low	31.7	Very low	112 Å²	112	151.1 Å²	151.1	78%	0.783	81%	0.807	S	S	*	*			trans	-160.4	85.4	151.3	-174.9	0	0	0	0	113.4
29	S	30.3	Very low	32.1	Very low	94 Å²	94	149.3 Å²	149.3	66%	0.657	80%	0.801	S	S	*	*			trans	38.2	111.3	132.6	-175.9	0	0	0	0	122
30	Y	29.5	Very low	31.9	Very low	235 Å²	235	146 Å²	146	92%	0.922	79%	0.79	S	S	*	*			trans	60.7	120.1	133.3	-78.9	-92	0	0	0	122.7
31	G	27.5	Very low	32.5	Very low	69 Å²	69	148.3 Å²	148.3	71%	0.711	79%	0.789	S	S	*	*				147	92.2	129.6	0	0	0	0	0	115.5
32	V	27.3	Very low	33.2	Very low	141 Å²	141	144.1 Å²	144.1	86%	0.855	78%	0.778	S	S	*	*			trans	170.4	120.8	131.7	156.5	0	0	0	0	108.9
33	N	30.6	Very low	33.6	Very low	152 Å²	152	136.8 Å²	136.8	81%	0.813	76%	0.757	S	S	*	*			trans	-63.4	129.7	166.1	-109.8	-2.3	0	0	0	109.2
34	D	28.6	Very low	33.9	Very low	144 Å²	144	134.1 Å²	134.1	77%	0.77	75%	0.748	S	S	*	*			trans	-162.4	124.4	131.5	-92.7	-28.2	0	0	0	110
35	S	36	Very low	34.4	Very low	111 Å²	111	132.6 Å²	132.6	78%	0.776	74%	0.739	S	S	*	*			trans	-72.6	121	-173	41.6	0	0	0	0	113
36	F	31.5	Very low	34.9	Very low	191 Å²	191	134.4 Å²	134.4	84%	0.838	74%	0.738	S	S	*	*			trans	-136.3	142.2	159.7	-81.8	-86.6	0	0	0	109.5
37	P	35.6	Very low	35.3	Very low	119 Å²	119	126.5 Å²	126.5	77%	0.773	73%	0.725	S	S	*	*			trans	-70.1	135.8	-169	28.6	-32.3	0	0	0	111.3	G39	P37-G39 PolarHBondContact O-N 2.93Å
38	D	37.5	Very low	36	Very low	171 Å²	171	120.6 Å²	120.6	91%	0.914	70%	0.698	S	S	*	*			trans	-52.3	100.1	177.2	-149.6	2.6	0	0	0	110.6
39	G	35	Very low	36.7	Very low	43 Å²	43	118.7 Å²	118.7	44%	0.443	69%	0.689	S	S	.	*			trans	-97.7	110.1	173.2	0	0	0	0	0	108.4	P37 Y41	P37-G39 PolarHBondContact O-N 2.93Å; G39-Y41 WeakPolarHBondContact O-CD2 3.38Å; G39-Y41 PolarHBondContact O-N 3.28Å
40	D	36.9	Very low	37.7	Very low	122 Å²	122	119.4 Å²	119.4	65%	0.652	69%	0.691	S	S	*	*			trans	-60.1	66	179.1	-170.7	16.4	0	0	0	113.4	A43	D40-A43 WeakPolarHBondContact OD1-CB 2.9Å
41	Y	40.5	Very low	39.1	Very low	192 Å²	192	110.5 Å²	110.5	75%	0.753	66%	0.663	S	S	*	*			trans	-99.4	-11.2	175.8	-71.6	-78.1	0	0	0	112.4	G39	G39-Y41 WeakPolarHBondContact O-CD2 3.38Å; G39-Y41 PolarHBondContact O-N 3.28Å
42	G	41.9	Very low	40.2	Very low	48 Å²	48	115.2 Å²	115.2	50%	0.495	67%	0.666	S	S	.	*	S	Bend	trans	-77.7	-40.9	179.8	0	0	0	0	0	113.6	N44 L45	G42-N44 PolarHBondContact O-N 3.44Å; G42-L45 PolarHBondContact O-N 2.95Å
43	A	39.9	Very low	41.6	Very low	57 Å²	57	113 Å²	113	47%	0.471	66%	0.657	S	S	.	*	H	α-helix	trans	-67.5	-23.2	-175.2	0	0	0	0	0	113.7	D40	D40-A43 WeakPolarHBondContact OD1-CB 2.9Å
44	N	42	Very low	42.6	Very low	124 Å²	124	110.7 Å²	110.7	66%	0.663	65%	0.652	S	S	*	*	H	α-helix	trans	-88.3	-13.8	179.6	-79	-43.3	0	0	0	114.2	G42	G42-N44 PolarHBondContact O-N 3.44Å
45	L	43.3	Very low	43.9	Very low	113 Å²	113	108.7 Å²	108.7	59%	0.592	64%	0.641	S	S	*	*	H	α-helix	trans	-80.6	-34.9	174.2	-84	169.6	0	0	0	111.6	L5 G42	L5-L45 HydrophobicContact CD1-CD2 3.51Å; G42-L45 PolarHBondContact O-N 2.95Å
46	E	45.7	Very low	44.6	Very low	184 Å²	184	111.5 Å²	111.5	86%	0.86	65%	0.646	S	S	*	*	H	α-helix	trans	-78.8	-19	179.5	-59.6	-165.9	159.5	0	0	113.4
47	A	43.4	Very low	45.9	Very low	78 Å²	78	106.5 Å²	106.5	65%	0.645	63%	0.628	S	S	*	*	T	Hydrogen-bonded Turn	trans	-87.9	-3.7	177.8	0	0	0	0	0	114.2	A49	A47-A49 PolarHBondContact O-N 3.13Å
48	A	46.2	Very low	47.3	Very low	32 Å²	32	105.7 Å²	105.7	26%	0.264	62%	0.617	S	S	.	*			trans	-79.9	108.3	179.2	0	0	0	0	0	110.4	L5	L5-A48 HydrophobicContact CD1-CB 4.24Å
49	A	41.8	Very low	48.6	Very low	73 Å²	73	102.4 Å²	102.4	60%	0.603	60%	0.599	S	S	*	*			trans	-58.3	137.3	171.6	0	0	0	0	0	110.3	A47 C51	A47-A49 PolarHBondContact O-N 3.13Å; A49-C51 PolarHBondContact O-N 3.39Å
50	P	51.9	Low	50.3	Low	109 Å²	109	105.8 Å²	105.8	71%	0.708	62%	0.616	S	S	*	*			trans	-58.7	135.9	176	22.4	-30.7	0	0	0	109.6	H52	P50-H52 VanDerWaalsContact C-N 3.32Å; P50-H52 PolarHBondContact O-N 2.87Å
51	C	56.9	Low	52.4	Low	48 Å²	48	100.7 Å²	100.7	32%	0.324	59%	0.591	S	S	.	*			trans	-67.2	93.1	177.4	-53.8	0	0	0	0	110.4	C4 A49 S53	C4-C51 WeakPolarHBondContact CA-SG 3.21Å; C4-C51 HydrophobicContact CB-CB 4.23Å; C4-C51 WeakPolarHBondContact CB-SG 3.3Å; C4-C51 PolarHBondContact O-SG 3.44Å; C4-C51 WeakPolarHBondContact SG-CA 3.5Å; C4-C51 WeakPolarHBondContact SG-CB 3.23Å; C4-C51 CovalentContact SG-SG 2.02Å; C4-C51 PolarHBondContact SG-SG 2.8Å; A49-C51 PolarHBondContact O-N 3.39Å; C51-S53 PolarHBondContact O-N 3.28Å
52	H	52.6	Low	54.4	Low	167 Å²	167	93.5 Å²	93.5	77%	0.773	57%	0.566	S	S	*	*			trans	-85.1	96.3	171.3	-149	41.9	0	0	0	108.4	P50 C54	P50-H52 VanDerWaalsContact C-N 3.32Å; P50-H52 PolarHBondContact O-N 2.87Å; H52-C54 PolarHBondContact O-N 2.88Å
53	S	55.6	Low	56.6	Low	95 Å²	95	95.5 Å²	95.5	66%	0.664	57%	0.57	S	S	*	*			trans	-78.9	104.1	163	179.8	0	0	0	0	107	C51 N55	C51-S53 PolarHBondContact O-N 3.28Å; S53-N55 PolarHBondContact O-N 3.22Å; S53-N55 VanDerWaalsContact O-N 3.17Å
54	C	52.1	Low	58.9	Low	104 Å²	104	98.9 Å²	98.9	70%	0.703	57%	0.574	S	S	*	*			trans	-62.9	115.9	168.5	-62.4	0	0	0	0	108.1	H52 L56	H52-C54 PolarHBondContact O-N 2.88Å; C54-L56 PolarHBondContact O-N 3.04Å
55	N	56	Low	61.1	Low	102 Å²	102	95.3 Å²	95.3	55%	0.545	55%	0.553	S	S	.	*			trans	-71.3	114.6	174.7	-88.3	-25.5	0	0	0	108.8	S53 L57 D58	S53-N55 PolarHBondContact O-N 3.22Å; S53-N55 VanDerWaalsContact O-N 3.17Å; N55-L57 PolarHBondContact O-N 2.98Å; N55-D58 WeakPolarHBondContact CB-OD1 3.18Å
56	L	50.2	Low	63.4	Low	170 Å²	170	93.2 Å²	93.2	89%	0.89	54%	0.542	S	S	*	.	S	Bend	trans	-66.2	-17.2	174.4	-141.8	163.3	0	0	0	111.4	C54	C54-L56 PolarHBondContact O-N 3.04Å
57	L	57.9	Low	65.6	Low	86 Å²	86	89.4 Å²	89.4	45%	0.45	53%	0.527	S	S	.	.	S	Bend	trans	-118.5	80.5	172.1	-74.2	87.6	0	0	0	109.5	N55 A61 F65	N55-L57 PolarHBondContact O-N 2.98Å; L57-A61 HydrophobicContact CB-CB 3.85Å; L57-A61 HydrophobicContact CD2-CB 3.87Å; L57-A61 HydrophobicContact CG-CB 3.97Å; L57-F65 HydrophobicContact CD2-CE2 3.63Å; L57-F65 HydrophobicContact CD2-CZ 3.53Å
58	D	65.3	Low	68	Low	101 Å²	101	88.2 Å²	88.2	54%	0.54	51%	0.511	S	S	.	.			trans	-76.8	-175	166.2	-82.2	-25.5	0	0	0	111	N55 S60 A61	N55-D58 WeakPolarHBondContact CB-OD1 3.18Å; D58-S60 PolarHBondContact O-N 3.49Å; D58-A61 WeakPolarHBondContact O-CB 3.29Å; D58-A61 PolarHBondContact O-N 2.84Å
59	D	65	Low	70.2	Confident	102 Å²	102	87 Å²	87	55%	0.545	50%	0.501	S	S	.	.	G	3₁₀ helix	trans	-49.8	-20.7	-177.5	-65	-35.1	0	0	0	114.8	A61 L62 G119	D59-A61 PolarHBondContact O-N 3.02Å; D59-L62 PolarHBondContact O-N 3.48Å; D59-G119 WeakPolarHBondContact OD1-CA 3.49Å; D59-G119 PolarHBondContact OD1-N 3.21Å
60	S	71.1	Confident	72.8	Confident	114 Å²	114	86.9 Å²	86.9	80%	0.797	49%	0.492	S	S	*	.	G	3₁₀ helix	trans	-68.7	-14.6	174.8	-62.5	0	0	0	0	114.5	D58 L62 P63	D58-S60 PolarHBondContact O-N 3.49Å; S60-L62 VanDerWaalsContact C-N 3.31Å; S60-P63 VanDerWaalsContact O-CD 3.27Å; S60-P63 WeakPolarHBondContact O-CD 3.34Å
61	A	80.2	Confident	74.9	Confident	16 Å²	16	86.5 Å²	86.5	13%	0.132	48%	0.484	C	S	.	.	G	3₁₀ helix	trans	-80.9	-10.2	178.5	0	0	0	0	0	113.5	L57 D58 D59 P63 F64 F65	L57-A61 HydrophobicContact CB-CB 3.85Å; L57-A61 HydrophobicContact CD2-CB 3.87Å; L57-A61 HydrophobicContact CG-CB 3.97Å; D58-A61 WeakPolarHBondContact O-CB 3.29Å; D58-A61 PolarHBondContact O-N 2.84Å; D59-A61 PolarHBondContact O-N 3.02Å; A61-P63 VanDerWaalsContact C-CD 3.43Å; A61-F64 WeakPolarHBondContact O-CB 3.24Å; A61-F64 PolarHBondContact O-N 3.1Å; A61-F65 HydrophobicContact CB-CD2 4.14Å; A61-F65 HydrophobicContact CB-CE2 3.84Å; A61-F65 VanDerWaalsContact O-CD2 3.28Å; A61-F65 WeakPolarHBondContact O-CD2 3.07Å; A61-F65 PolarHBondContact O-N 3.02Å
62	L	83.3	Confident	76.7	Confident	41 Å²	41	85 Å²	85	22%	0.215	48%	0.476	C	S	.	.	H	α-helix	trans	-49.8	-47.1	-178.8	-178.4	68.7	0	0	0	113.6	D59 S60 F64 F65 I66 A117 P118 L120	D59-L62 PolarHBondContact O-N 3.48Å; S60-L62 VanDerWaalsContact C-N 3.31Å; L62-F64 PolarHBondContact O-N 3.27Å; L62-F65 PolarHBondContact O-N 3.01Å; L62-F65 VanDerWaalsContact O-N 3.12Å; L62-I66 HydrophobicContact CD1-CD1 4.4Å; L62-I66 HydrophobicContact CD1-CG1 4.29Å; L62-I66 HydrophobicContact CG-CG1 4.31Å; L62-I66 WeakPolarHBondContact O-CG1 3.4Å; L62-I66 PolarHBondContact O-N 3.32Å; L62-A117 HydrophobicContact CD1-CB 3.95Å; L62-P118 WeakPolarHBondContact CD1-O 3.42Å; L62-L120 HydrophobicContact CD1-CD1 3.45Å; L62-L120 VanDerWaalsContact CD1-CD1 3.45Å; L62-L120 HydrophobicContact CD1-CG 4.04Å
63	P	87.1	Confident	78.8	Confident	90 Å²	90	79.6 Å²	79.6	58%	0.584	45%	0.453	S	S	*	.	H	α-helix	trans	-60.9	-33.1	-179.2	-22.4	35	0	0	0	113.2	S60 A61 I66 L67	S60-P63 VanDerWaalsContact O-CD 3.27Å; S60-P63 WeakPolarHBondContact O-CD 3.34Å; A61-P63 VanDerWaalsContact C-CD 3.43Å; P63-I66 PolarHBondContact O-N 3.11Å; P63-L67 VanDerWaalsContact O-CB 3.31Å; P63-L67 WeakPolarHBondContact O-CB 3.46Å; P63-L67 PolarHBondContact O-N 2.81Å
64	F	88.8	Confident	80.7	Confident	128 Å²	128	79.9 Å²	79.9	56%	0.561	45%	0.446	S	S	*	.	H	α-helix	trans	-67.9	-43.9	176.1	175.4	-96.2	0	0	0	111.4	A61 L62 I66 L67 T68	A61-F64 WeakPolarHBondContact O-CB 3.24Å; A61-F64 PolarHBondContact O-N 3.1Å; L62-F64 PolarHBondContact O-N 3.27Å; F64-I66 VanDerWaalsContact C-N 3.35Å; F64-I66 PolarHBondContact O-N 2.68Å; F64-L67 PolarHBondContact O-N 2.91Å; F64-T68 HydrophobicContact CD1-CG2 4.31Å; F64-T68 HydrophobicContact CD2-CG2 4.29Å; F64-T68 HydrophobicContact CE1-CG2 3.91Å; F64-T68 HydrophobicContact CE2-CG2 3.9Å; F64-T68 HydrophobicContact CG-CG2 4.49Å; F64-T68 HydrophobicContact CZ-CG2 3.69Å; F64-T68 WeakPolarHBondContact O-CB 3.29Å; F64-T68 VanDerWaalsContact O-CG2 3.3Å; F64-T68 WeakPolarHBondContact O-CG2 3.26Å; F64-T68 PolarHBondContact O-N 2.91Å; F64-T68 PolarHBondContact O-OG1 2.93Å
65	F	88.4	Confident	82.8	Confident	48 Å²	48	77.7 Å²	77.7	21%	0.211	44%	0.436	C	S	.	.	H	α-helix	trans	-63.5	-39.2	175.2	-73.1	-68.7	0	0	0	112.5	L57 A61 L62 T68 S69 V113 A117 P118	L57-F65 HydrophobicContact CD2-CE2 3.63Å; L57-F65 HydrophobicContact CD2-CZ 3.53Å; A61-F65 HydrophobicContact CB-CD2 4.14Å; A61-F65 HydrophobicContact CB-CE2 3.84Å; A61-F65 VanDerWaalsContact O-CD2 3.28Å; A61-F65 WeakPolarHBondContact O-CD2 3.07Å; A61-F65 PolarHBondContact O-N 3.02Å; L62-F65 PolarHBondContact O-N 3.01Å; L62-F65 VanDerWaalsContact O-N 3.12Å; F65-T68 WeakPolarHBondContact CA-OG1 3.28Å; F65-T68 PolarHBondContact O-OG1 3.33Å; F65-S69 WeakPolarHBondContact O-CB 3.35Å; F65-S69 PolarHBondContact O-N 3.38Å; F65-V113 HydrophobicContact CB-CG1 3.88Å; F65-V113 HydrophobicContact CD1-CG1 3.6Å; F65-V113 HydrophobicContact CG-CG1 4.2Å; F65-A117 HydrophobicContact CB-CB 3.64Å; F65-A117 HydrophobicContact CD1-CB 4.47Å; F65-A117 HydrophobicContact CD2-CB 3.79Å; F65-A117 HydrophobicContact CG-CB 3.73Å; F65-P118 HydrophobicContact CE2-CG 4.09Å
66	I	90.9	Very high	84.6	Confident	70 Å²	70	73.3 Å²	73.3	36%	0.359	41%	0.413	S	S	.	.	H	α-helix	trans	-65.2	-48.2	174.9	-62	-58	0	0	0	110.9	L62 P63 F64 T68 S69 V70 P114	L62-I66 HydrophobicContact CD1-CD1 4.4Å; L62-I66 HydrophobicContact CD1-CG1 4.29Å; L62-I66 HydrophobicContact CG-CG1 4.31Å; L62-I66 WeakPolarHBondContact O-CG1 3.4Å; L62-I66 PolarHBondContact O-N 3.32Å; P63-I66 PolarHBondContact O-N 3.11Å; F64-I66 VanDerWaalsContact C-N 3.35Å; F64-I66 PolarHBondContact O-N 2.68Å; I66-T68 PolarHBondContact O-N 2.96Å; I66-S69 WeakPolarHBondContact O-CB 3.38Å; I66-S69 PolarHBondContact O-N 3.48Å; I66-V70 HydrophobicContact CG2-CG2 4.37Å; I66-V70 WeakPolarHBondContact O-CG2 3.31Å; I66-V70 PolarHBondContact O-N 3.19Å; I66-P114 HydrophobicContact CD1-CB 3.72Å; I66-P114 HydrophobicContact CD1-CG 3.97Å
67	L	93.3	Very high	86.6	Confident	104 Å²	104	68 Å²	68	55%	0.545	39%	0.39	S	S	.	.	H	α-helix	trans	-60.8	-47.2	-179.1	-176.2	71.9	0	0	0	111.6	P63 F64 S69 V70 L71	P63-L67 VanDerWaalsContact O-CB 3.31Å; P63-L67 WeakPolarHBondContact O-CB 3.46Å; P63-L67 PolarHBondContact O-N 2.81Å; F64-L67 PolarHBondContact O-N 2.91Å; L67-S69 VanDerWaalsContact C-N 3.34Å; L67-S69 PolarHBondContact O-N 3.43Å; L67-V70 PolarHBondContact O-N 3.39Å; L67-L71 HydrophobicContact CD1-CD1 4.44Å; L67-L71 HydrophobicContact CG-CD1 4.09Å; L67-L71 WeakPolarHBondContact O-CB 3.43Å; L67-L71 WeakPolarHBondContact O-CG 3.23Å; L67-L71 PolarHBondContact O-N 3.2Å
68	T	92.6	Very high	88.3	Confident	53 Å²	53	67.5 Å²	67.5	33%	0.325	39%	0.391	S	S	.	.	H	α-helix	trans	-64	-39.9	178.4	51.5	0	0	0	0	111.7	F64 F65 I66 G72	F64-T68 HydrophobicContact CD1-CG2 4.31Å; F64-T68 HydrophobicContact CD2-CG2 4.29Å; F64-T68 HydrophobicContact CE1-CG2 3.91Å; F64-T68 HydrophobicContact CE2-CG2 3.9Å; F64-T68 HydrophobicContact CG-CG2 4.49Å; F64-T68 HydrophobicContact CZ-CG2 3.69Å; F64-T68 WeakPolarHBondContact O-CB 3.29Å; F64-T68 VanDerWaalsContact O-CG2 3.3Å; F64-T68 WeakPolarHBondContact O-CG2 3.26Å; F64-T68 PolarHBondContact O-N 2.91Å; F64-T68 PolarHBondContact O-OG1 2.93Å; F65-T68 WeakPolarHBondContact CA-OG1 3.28Å; F65-T68 PolarHBondContact O-OG1 3.33Å; I66-T68 PolarHBondContact O-N 2.96Å; T68-G72 PolarHBondContact O-N 3.47Å
69	S	93.9	Very high	89.5	Confident	5 Å²	5	65.3 Å²	65.3	4%	0.035	38%	0.381	C	S	.	.	H	α-helix	trans	-59.2	-51.5	173.4	175.9	0	0	0	0	111.9	F65 I66 L67 L71 G72 I73 S110 P114	F65-S69 WeakPolarHBondContact O-CB 3.35Å; F65-S69 PolarHBondContact O-N 3.38Å; I66-S69 WeakPolarHBondContact O-CB 3.38Å; I66-S69 PolarHBondContact O-N 3.48Å; L67-S69 VanDerWaalsContact C-N 3.34Å; L67-S69 PolarHBondContact O-N 3.43Å; S69-L71 PolarHBondContact O-N 3.06Å; S69-G72 PolarHBondContact O-N 2.91Å; S69-I73 VanDerWaalsContact O-CG1 3.23Å; S69-I73 WeakPolarHBondContact O-CG1 3.24Å; S69-I73 PolarHBondContact O-N 3.4Å; S69-S110 VanDerWaalsContact CB-O 3.28Å; S69-S110 WeakPolarHBondContact CB-O 3.29Å; S69-S110 PolarHBondContact OG-O 3.22Å; S69-P114 WeakPolarHBondContact OG-CD 3.39Å; S69-P114 VanDerWaalsContact OG-CG 3.31Å; S69-P114 WeakPolarHBondContact OG-CG 3.38Å
70	V	96.3	Very high	90.7	Very high	71 Å²	71	61.7 Å²	61.7	43%	0.43	36%	0.361	S	S	.	.	H	α-helix	trans	-61.2	-47.3	-179.5	171.1	0	0	0	0	111.3	I66 L67 G72 I73 L74	I66-V70 HydrophobicContact CG2-CG2 4.37Å; I66-V70 WeakPolarHBondContact O-CG2 3.31Å; I66-V70 PolarHBondContact O-N 3.19Å; L67-V70 PolarHBondContact O-N 3.39Å; V70-G72 VanDerWaalsContact C-N 3.34Å; V70-G72 PolarHBondContact O-N 3.35Å; V70-I73 PolarHBondContact O-N 3.33Å; V70-L74 HydrophobicContact CG1-CD1 3.84Å; V70-L74 HydrophobicContact CG1-CG 4.39Å; V70-L74 WeakPolarHBondContact O-CB 3.24Å; V70-L74 VanDerWaalsContact O-CG 3.29Å; V70-L74 WeakPolarHBondContact O-CG 3.42Å; V70-L74 PolarHBondContact O-N 2.86Å
71	L	96.3	Very high	91.5	Very high	102 Å²	102	62.6 Å²	62.6	53%	0.534	35%	0.351	S	S	.	.	H	α-helix	trans	-62.1	-42.8	177.4	-72.5	172.7	0	0	0	111.7	L67 S69 L74 A75	L67-L71 HydrophobicContact CD1-CD1 4.44Å; L67-L71 HydrophobicContact CG-CD1 4.09Å; L67-L71 WeakPolarHBondContact O-CB 3.43Å; L67-L71 WeakPolarHBondContact O-CG 3.23Å; L67-L71 PolarHBondContact O-N 3.2Å; S69-L71 PolarHBondContact O-N 3.06Å; L71-L74 PolarHBondContact O-N 2.97Å; L71-A75 VanDerWaalsContact O-CB 3.24Å; L71-A75 WeakPolarHBondContact O-CB 3.35Å; L71-A75 PolarHBondContact O-N 3.22Å
72	G	94.4	Very high	91.9	Very high	16 Å²	16	65.4 Å²	65.4	17%	0.165	36%	0.362	C	S	.	.	H	α-helix	trans	-62.7	-43.2	178	0	0	0	0	0	112.5	T68 S69 V70 S76 S110	T68-G72 PolarHBondContact O-N 3.47Å; S69-G72 PolarHBondContact O-N 2.91Å; V70-G72 VanDerWaalsContact C-N 3.34Å; V70-G72 PolarHBondContact O-N 3.35Å; G72-S76 WeakPolarHBondContact O-CB 3.42Å; G72-S76 PolarHBondContact O-N 3.29Å; G72-S76 PolarHBondContact O-OG 3.41Å; G72-S110 WeakPolarHBondContact CA-OG 3.2Å
73	I	95.8	Very high	91.8	Very high	53 Å²	53	64 Å²	64	27%	0.272	36%	0.355	S	S	.	.	H	α-helix	trans	-62.6	-53	174.6	-66.6	164.1	0	0	0	110.1	S69 V70 A75 S76 S77 I111	S69-I73 VanDerWaalsContact O-CG1 3.23Å; S69-I73 WeakPolarHBondContact O-CG1 3.24Å; S69-I73 PolarHBondContact O-N 3.4Å; V70-I73 PolarHBondContact O-N 3.33Å; I73-A75 PolarHBondContact O-N 2.75Å; I73-S76 PolarHBondContact O-N 3.3Å; I73-S77 VanDerWaalsContact O-CB 3.26Å; I73-S77 WeakPolarHBondContact O-CB 3.36Å; I73-S77 PolarHBondContact O-N 3.36Å; I73-S77 PolarHBondContact O-OG 3.06Å; I73-S77 VanDerWaalsContact O-OG 3.05Å; I73-I111 HydrophobicContact CD1-CG1 3.87Å; I73-I111 HydrophobicContact CG1-CG1 3.89Å
74	L	96.3	Very high	91.4	Very high	102 Å²	102	66.1 Å²	66.1	53%	0.534	36%	0.355	S	S	.	.	H	α-helix	trans	-59.6	-45.9	-177.8	-72.5	173.3	0	0	0	112.1	V70 L71 T78	V70-L74 HydrophobicContact CG1-CD1 3.84Å; V70-L74 HydrophobicContact CG1-CG 4.39Å; V70-L74 WeakPolarHBondContact O-CB 3.24Å; V70-L74 VanDerWaalsContact O-CG 3.29Å; V70-L74 WeakPolarHBondContact O-CG 3.42Å; V70-L74 PolarHBondContact O-N 2.86Å; L71-L74 PolarHBondContact O-N 2.97Å; L74-T78 VanDerWaalsContact O-CB 3.28Å; L74-T78 WeakPolarHBondContact O-CB 3.49Å; L74-T78 PolarHBondContact O-N 3.17Å; L74-T78 PolarHBondContact O-OG1 3.47Å
75	A	95.1	Very high	91.1	Very high	58 Å²	58	65.2 Å²	65.2	48%	0.479	35%	0.348	S	S	.	.	H	α-helix	trans	-62.1	-48.9	178	0	0	0	0	0	111.2	L71 I73 T78 V79	L71-A75 VanDerWaalsContact O-CB 3.24Å; L71-A75 WeakPolarHBondContact O-CB 3.35Å; L71-A75 PolarHBondContact O-N 3.22Å; I73-A75 PolarHBondContact O-N 2.75Å; A75-T78 PolarHBondContact O-N 3.03Å; A75-V79 WeakPolarHBondContact O-CG2 3.27Å; A75-V79 PolarHBondContact O-N 3.42Å
76	S	94.4	Very high	89.8	Confident	10 Å²	10	69.1 Å²	69.1	7%	0.07	38%	0.379	C	S	.	.	H	α-helix	trans	-65	-44.7	-178.5	-57	0	0	0	0	112	G72 I73 T78 V79 L80 A103 S106 A107	G72-S76 WeakPolarHBondContact O-CB 3.42Å; G72-S76 PolarHBondContact O-N 3.29Å; G72-S76 PolarHBondContact O-OG 3.41Å; I73-S76 PolarHBondContact O-N 3.3Å; S76-T78 VanDerWaalsContact C-N 3.34Å; S76-T78 PolarHBondContact O-N 2.9Å; S76-V79 PolarHBondContact O-N 2.92Å; S76-L80 WeakPolarHBondContact O-CG 3.42Å; S76-L80 PolarHBondContact O-N 3.4Å; S76-A103 WeakPolarHBondContact CB-O 3.31Å; S76-S106 VanDerWaalsContact OG-CB 3.27Å; S76-S106 WeakPolarHBondContact OG-CB 3.17Å; S76-A107 PolarHBondContact OG-N 3.38Å
77	S	92.8	Very high	88.3	Confident	57 Å²	57	71.9 Å²	71.9	40%	0.399	39%	0.393	S	S	.	.	H	α-helix	trans	-64.2	-37.5	176.3	-65.7	0	0	0	0	112.1	I73 L80 F81	I73-S77 VanDerWaalsContact O-CB 3.26Å; I73-S77 WeakPolarHBondContact O-CB 3.36Å; I73-S77 PolarHBondContact O-N 3.36Å; I73-S77 PolarHBondContact O-OG 3.06Å; I73-S77 VanDerWaalsContact O-OG 3.05Å; S77-L80 PolarHBondContact O-N 3.04Å; S77-F81 WeakPolarHBondContact O-CB 3.26Å; S77-F81 PolarHBondContact O-N 3.46Å
78	T	92.8	Very high	86.6	Confident	77 Å²	77	71.6 Å²	71.6	47%	0.472	39%	0.388	S	S	.	.	H	α-helix	trans	-64.9	-44.4	175.8	-59	0	0	0	0	111	L74 A75 S76 F81 M82	L74-T78 VanDerWaalsContact O-CB 3.28Å; L74-T78 WeakPolarHBondContact O-CB 3.49Å; L74-T78 PolarHBondContact O-N 3.17Å; L74-T78 PolarHBondContact O-OG1 3.47Å; A75-T78 PolarHBondContact O-N 3.03Å; S76-T78 VanDerWaalsContact C-N 3.34Å; S76-T78 PolarHBondContact O-N 2.9Å; T78-F81 PolarHBondContact O-N 2.97Å; T78-M82 VanDerWaalsContact O-CG 3.3Å; T78-M82 WeakPolarHBondContact O-CG 3.44Å; T78-M82 PolarHBondContact O-N 3.25Å
79	V	90.4	Very high	85.1	Confident	54 Å²	54	78.5 Å²	78.5	33%	0.327	41%	0.408	S	S	.	.	H	α-helix	trans	-58.6	-55.1	174.1	172.2	0	0	0	0	109.5	A75 S76 F81 M82 L83 L99 A103	A75-V79 WeakPolarHBondContact O-CG2 3.27Å; A75-V79 PolarHBondContact O-N 3.42Å; S76-V79 PolarHBondContact O-N 2.92Å; V79-F81 VanDerWaalsContact C-N 3.29Å; V79-F81 PolarHBondContact O-N 3.05Å; V79-M82 PolarHBondContact O-N 2.88Å; V79-M82 VanDerWaalsContact O-N 3.13Å; V79-L83 HydrophobicContact CG1-CD1 4Å; V79-L83 HydrophobicContact CG1-CG 4.02Å; V79-L83 VanDerWaalsContact O-CB 3.29Å; V79-L83 WeakPolarHBondContact O-CB 3.35Å; V79-L83 WeakPolarHBondContact O-CG 3.41Å; V79-L83 PolarHBondContact O-N 3.29Å; V79-L99 HydrophobicContact CG1-CG 4.31Å; V79-A103 HydrophobicContact CB-CB 4.29Å; V79-A103 HydrophobicContact CG1-CB 3.93Å
80	L	90.2	Very high	83.5	Confident	27 Å²	27	85.6 Å²	85.6	14%	0.141	43%	0.434	C	S	.	.	H	α-helix	trans	-55.7	-43	178.8	-70.6	169.7	0	0	0	112.4	S76 S77 L83 F84 A100 A103 V104	S76-L80 WeakPolarHBondContact O-CG 3.42Å; S76-L80 PolarHBondContact O-N 3.4Å; S77-L80 PolarHBondContact O-N 3.04Å; L80-L83 WeakPolarHBondContact O-CB 3.31Å; L80-L83 PolarHBondContact O-N 3.39Å; L80-F84 HydrophobicContact CB-CD2 4.29Å; L80-F84 HydrophobicContact CB-CE2 4.25Å; L80-F84 HydrophobicContact CD2-CE2 3.9Å; L80-F84 WeakPolarHBondContact O-CD2 3.21Å; L80-F84 PolarHBondContact O-N 2.88Å; L80-A100 HydrophobicContact CD2-CB 4.44Å; L80-A103 HydrophobicContact CD1-CB 4.45Å; L80-A103 HydrophobicContact CD2-CB 3.87Å; L80-A103 HydrophobicContact CG-CB 3.81Å; L80-V104 HydrophobicContact CD1-CG2 4.21Å; L80-V104 HydrophobicContact CD2-CG2 3.93Å
81	F	89.3	Confident	81.7	Confident	132 Å²	132	91.2 Å²	91.2	58%	0.579	46%	0.455	S	S	*	.	H	α-helix	trans	-61.5	-46.9	177.5	178.4	-100.7	0	0	0	111.9	S77 T78 V79 L83 F84 R85	S77-F81 WeakPolarHBondContact O-CB 3.26Å; S77-F81 PolarHBondContact O-N 3.46Å; T78-F81 PolarHBondContact O-N 2.97Å; V79-F81 VanDerWaalsContact C-N 3.29Å; V79-F81 PolarHBondContact O-N 3.05Å; F81-L83 VanDerWaalsContact C-N 3.27Å; F81-L83 PolarHBondContact O-N 2.69Å; F81-F84 PolarHBondContact O-N 3Å; F81-R85 WeakPolarHBondContact O-CB 3.18Å; F81-R85 PolarHBondContact O-N 3.47Å
82	M	86.8	Confident	79.8	Confident	75 Å²	75	92.2 Å²	92.2	37%	0.369	46%	0.461	S	S	.	.	H	α-helix	trans	-60.2	-42.3	175	-70.2	-64.9	-176.3	0	0	111.1	T78 V79 R85 F88	T78-M82 VanDerWaalsContact O-CG 3.3Å; T78-M82 WeakPolarHBondContact O-CG 3.44Å; T78-M82 PolarHBondContact O-N 3.25Å; V79-M82 PolarHBondContact O-N 2.88Å; V79-M82 VanDerWaalsContact O-N 3.13Å; M82-R85 PolarHBondContact O-N 2.89Å; M82-F88 HydrophobicContact CB-CD2 4.46Å; M82-F88 HydrophobicContact CB-CE2 3.82Å; M82-F88 HydrophobicContact CB-CZ 4.32Å; M82-F88 HydrophobicContact CG-CE2 4.47Å; M82-F88 WeakPolarHBondContact O-CD2 3.39Å; M82-F88 WeakPolarHBondContact O-CG 3.28Å; M82-F88 HydrophobicContact SD-CE2 4.12Å
83	L	81.9	Confident	78.4	Confident	13 Å²	13	94.8 Å²	94.8	7%	0.068	48%	0.476	C	S	.	.	H	α-helix	trans	-64.3	-40.6	-178.8	-76.3	-153.5	0	0	0	113.5	V79 L80 F81 W90 W96 L99 A100	V79-L83 HydrophobicContact CG1-CD1 4Å; V79-L83 HydrophobicContact CG1-CG 4.02Å; V79-L83 VanDerWaalsContact O-CB 3.29Å; V79-L83 WeakPolarHBondContact O-CB 3.35Å; V79-L83 WeakPolarHBondContact O-CG 3.41Å; V79-L83 PolarHBondContact O-N 3.29Å; L80-L83 WeakPolarHBondContact O-CB 3.31Å; L80-L83 PolarHBondContact O-N 3.39Å; F81-L83 VanDerWaalsContact C-N 3.27Å; F81-L83 PolarHBondContact O-N 2.69Å; L83-W90 PolarHBondContact O-NE1 3.4Å; L83-W96 HydrophobicContact CB-CZ2 3.83Å; L83-W96 HydrophobicContact CD1-CG 4.47Å; L83-W96 VanDerWaalsContact CD1-NE1 3.31Å; L83-W96 VanDerWaalsContact O-CZ2 3.23Å; L83-W96 WeakPolarHBondContact O-CZ2 3.3Å; L83-W96 PolarHBondContact O-NE1 2.89Å; L83-L99 HydrophobicContact CD1-CB 4.29Å; L83-L99 HydrophobicContact CD1-CD2 4.24Å; L83-L99 HydrophobicContact CD1-CG 4.1Å; L83-L99 HydrophobicContact CD2-CD2 4.24Å; L83-A100 HydrophobicContact CD1-CB 3.82Å
84	F	79.4	Confident	76.9	Confident	133 Å²	133	97.2 Å²	97.2	58%	0.583	50%	0.495	S	S	*	.	H	α-helix	trans	-87.4	-8.1	178.8	-69	-60.7	0	0	0	114	L80 F81 W96	L80-F84 HydrophobicContact CB-CD2 4.29Å; L80-F84 HydrophobicContact CB-CE2 4.25Å; L80-F84 HydrophobicContact CD2-CE2 3.9Å; L80-F84 WeakPolarHBondContact O-CD2 3.21Å; L80-F84 PolarHBondContact O-N 2.88Å; F81-F84 PolarHBondContact O-N 3Å; F84-W96 HydrophobicContact CD1-CH2 4.16Å; F84-W96 HydrophobicContact CD1-CZ2 4.08Å; F84-W96 AromaticContact CE1-CH2 3.9Å; F84-W96 HydrophobicContact CE1-CH2 3.9Å; F84-W96 HydrophobicContact CE1-CZ2 4.09Å
85	R	81.2	Confident	75.7	Confident	109 Å²	109	94 Å²	94	41%	0.411	49%	0.486	S	S	.	.	S	Bend	trans	-67	129	179.2	-165.8	172.8	-179.4	177.8	-1.2	109.6	F81 M82 L87 F88	F81-R85 WeakPolarHBondContact O-CB 3.18Å; F81-R85 PolarHBondContact O-N 3.47Å; M82-R85 PolarHBondContact O-N 2.89Å; R85-L87 HydrophobicContact CG-CB 4.45Å; R85-L87 HydrophobicContact CG-CG 4.46Å; R85-L87 PolarHBondContact O-N 3.13Å; R85-F88 PolarHBondContact O-N 2.91Å
86	P	61.8	Low	74.9	Confident	131 Å²	131	92.4 Å²	92.4	85%	0.851	47%	0.467	S	S	*	.	T	Hydrogen-bonded Turn	trans	-65.2	1.2	-176.1	24.7	-34.2	0	0	0	115
87	L	59.6	Low	74.3	Confident	127 Å²	127	93.6 Å²	93.6	67%	0.665	48%	0.475	S	S	*	.	T	Hydrogen-bonded Turn	trans	-91	-17.9	175.5	-61	177.9	0	0	0	112.9	R85 R89	R85-L87 HydrophobicContact CG-CB 4.45Å; R85-L87 HydrophobicContact CG-CG 4.46Å; R85-L87 PolarHBondContact O-N 3.13Å; L87-R89 PolarHBondContact O-N 3.45Å; L87-R89 VanDerWaalsContact O-N 3.14Å
88	F	56.8	Low	73.9	Confident	99 Å²	99	92.6 Å²	92.6	43%	0.434	47%	0.466	S	S	.	.	S	Bend	trans	-75.4	104.6	173.9	-98	-92.9	0	0	0	108.8	M82 R85 W90	M82-F88 HydrophobicContact CB-CD2 4.46Å; M82-F88 HydrophobicContact CB-CE2 3.82Å; M82-F88 HydrophobicContact CB-CZ 4.32Å; M82-F88 HydrophobicContact CG-CE2 4.47Å; M82-F88 WeakPolarHBondContact O-CD2 3.39Å; M82-F88 WeakPolarHBondContact O-CG 3.28Å; M82-F88 HydrophobicContact SD-CE2 4.12Å; R85-F88 PolarHBondContact O-N 2.91Å; F88-W90 VanDerWaalsContact C-N 3.32Å; F88-W90 PolarHBondContact O-N 2.81Å
89	R	61.7	Low	73.7	Confident	197 Å²	197	93 Å²	93	74%	0.743	47%	0.465	S	S	*	.			trans	-61.5	96	170.4	-66.6	179.2	-174.8	-178.3	1.6	107.7	L87 Q91 L92	L87-R89 PolarHBondContact O-N 3.45Å; L87-R89 VanDerWaalsContact O-N 3.14Å; R89-Q91 PolarHBondContact O-N 3.42Å; R89-L92 HydrophobicContact CB-CD1 3.45Å; R89-L92 VanDerWaalsContact CB-CD1 3.45Å; R89-L92 HydrophobicContact CG-CD1 4.25Å; R89-L92 PolarHBondContact O-N 3.28Å
90	W	61	Low	73.6	Confident	155 Å²	155	90.8 Å²	90.8	59%	0.587	45%	0.452	S	S	*	.	G	3₁₀ helix	trans	-51.4	-23.3	-179.7	-82.6	15.9	0	0	0	113.6	L83 F88 L92 C93 W96	L83-W90 PolarHBondContact O-NE1 3.4Å; F88-W90 VanDerWaalsContact C-N 3.32Å; F88-W90 PolarHBondContact O-N 2.81Å; W90-L92 PolarHBondContact O-N 2.87Å; W90-C93 PolarHBondContact O-N 3.35Å; W90-W96 HydrophobicContact CD2-CE3 4Å; W90-W96 HydrophobicContact CD2-CZ3 4.01Å; W90-W96 AromaticContact CE2-CE3 3.76Å; W90-W96 AromaticContact CE2-CH2 3.54Å; W90-W96 AromaticContact CE2-CZ2 3.88Å; W90-W96 AromaticContact CE2-CZ3 3.44Å; W90-W96 VanDerWaalsContact CE2-CZ3 3.44Å; W90-W96 HydrophobicContact CE3-CE3 4.3Å; W90-W96 HydrophobicContact CE3-CZ3 4.16Å; W90-W96 HydrophobicContact CH2-CE3 4.22Å; W90-W96 AromaticContact CH2-CH2 3.61Å; W90-W96 HydrophobicContact CH2-CH2 3.61Å; W90-W96 AromaticContact CH2-CZ3 3.31Å; W90-W96 HydrophobicContact CH2-CZ3 3.31Å; W90-W96 AromaticContact CZ2-CE3 3.92Å; W90-W96 HydrophobicContact CZ2-CE3 3.92Å; W90-W96 AromaticContact CZ2-CH2 3.02Å; W90-W96 HydrophobicContact CZ2-CH2 3.02Å; W90-W96 AromaticContact CZ2-CZ2 3.75Å; W90-W96 HydrophobicContact CZ2-CZ2 3.75Å; W90-W96 AromaticContact CZ2-CZ3 3.1Å; W90-W96 HydrophobicContact CZ2-CZ3 3.1Å; W90-W96 HydrophobicContact CZ3-CE3 4.4Å; W90-W96 AromaticContact CZ3-CZ3 3.84Å; W90-W96 HydrophobicContact CZ3-CZ3 3.84Å; W90-W96 AromaticContact NE1-CE2 3.8Å; W90-W96 AromaticContact NE1-CH2 3.95Å; W90-W96 AromaticContact NE1-CZ2 3.78Å
91	Q	57.6	Low	73.7	Confident	188 Å²	188	92 Å²	92	88%	0.879	46%	0.457	S	S	*	.	G	3₁₀ helix	trans	-64.7	-16.6	172.9	-72.3	176.4	-23	0	0	114.8	R89	R89-Q91 PolarHBondContact O-N 3.42Å
92	L	57.2	Low	73.9	Confident	124 Å²	124	87.2 Å²	87.2	65%	0.649	44%	0.437	S	S	*	.	G	3₁₀ helix	trans	-84.6	-13.1	179.6	-87.9	89.4	0	0	0	114	R89 W90	R89-L92 HydrophobicContact CB-CD1 3.45Å; R89-L92 VanDerWaalsContact CB-CD1 3.45Å; R89-L92 HydrophobicContact CG-CD1 4.25Å; R89-L92 PolarHBondContact O-N 3.28Å; W90-L92 PolarHBondContact O-N 2.87Å
93	C	63.7	Low	74.3	Confident	70 Å²	70	84 Å²	84	47%	0.473	42%	0.423	S	S	.	.			trans	-138.9	89.6	-177.9	-73.8	0	0	0	0	112	W90 G95 W96	W90-C93 PolarHBondContact O-N 3.35Å; C93-G95 PolarHBondContact O-N 3.25Å; C93-W96 HydrophobicContact CB-CB 4.31Å; C93-W96 WeakPolarHBondContact O-CB 3.31Å; C93-W96 PolarHBondContact O-N 3.45Å
94	P	64.4	Low	74.9	Confident	104 Å²	104	85.7 Å²	85.7	68%	0.675	43%	0.433	S	S	*	.	T	Hydrogen-bonded Turn	trans	-61	-12.1	178.5	20.9	-30.6	0	0	0	114.6
95	G	71.9	Confident	75.6	Confident	33 Å²	33	79.3 Å²	79.3	34%	0.34	41%	0.406	S	S	.	.	T	Hydrogen-bonded Turn	trans	-98	4.8	176	0	0	0	0	0	115.7	C93 P97 V98 L99	C93-G95 PolarHBondContact O-N 3.25Å; G95-P97 VanDerWaalsContact C-CD 3.48Å; G95-V98 PolarHBondContact O-N 3.39Å; G95-L99 PolarHBondContact O-N 2.94Å
96	W	78.3	Confident	76.3	Confident	26 Å²	26	75.9 Å²	75.9	10%	0.098	40%	0.398	C	S	.	.	H	α-helix	trans	-54.5	-42.5	-174	174.8	80.1	0	0	0	115.2	L83 F84 W90 C93 V98 L99 A100	L83-W96 HydrophobicContact CB-CZ2 3.83Å; L83-W96 HydrophobicContact CD1-CG 4.47Å; L83-W96 VanDerWaalsContact CD1-NE1 3.31Å; L83-W96 VanDerWaalsContact O-CZ2 3.23Å; L83-W96 WeakPolarHBondContact O-CZ2 3.3Å; L83-W96 PolarHBondContact O-NE1 2.89Å; F84-W96 HydrophobicContact CD1-CH2 4.16Å; F84-W96 HydrophobicContact CD1-CZ2 4.08Å; F84-W96 AromaticContact CE1-CH2 3.9Å; F84-W96 HydrophobicContact CE1-CH2 3.9Å; F84-W96 HydrophobicContact CE1-CZ2 4.09Å; W90-W96 HydrophobicContact CD2-CE3 4Å; W90-W96 HydrophobicContact CD2-CZ3 4.01Å; W90-W96 AromaticContact CE2-CE3 3.76Å; W90-W96 AromaticContact CE2-CH2 3.54Å; W90-W96 AromaticContact CE2-CZ2 3.88Å; W90-W96 AromaticContact CE2-CZ3 3.44Å; W90-W96 VanDerWaalsContact CE2-CZ3 3.44Å; W90-W96 HydrophobicContact CE3-CE3 4.3Å; W90-W96 HydrophobicContact CE3-CZ3 4.16Å; W90-W96 HydrophobicContact CH2-CE3 4.22Å; W90-W96 AromaticContact CH2-CH2 3.61Å; W90-W96 HydrophobicContact CH2-CH2 3.61Å; W90-W96 AromaticContact CH2-CZ3 3.31Å; W90-W96 HydrophobicContact CH2-CZ3 3.31Å; W90-W96 AromaticContact CZ2-CE3 3.92Å; W90-W96 HydrophobicContact CZ2-CE3 3.92Å; W90-W96 AromaticContact CZ2-CH2 3.02Å; W90-W96 HydrophobicContact CZ2-CH2 3.02Å; W90-W96 AromaticContact CZ2-CZ2 3.75Å; W90-W96 HydrophobicContact CZ2-CZ2 3.75Å; W90-W96 AromaticContact CZ2-CZ3 3.1Å; W90-W96 HydrophobicContact CZ2-CZ3 3.1Å; W90-W96 HydrophobicContact CZ3-CE3 4.4Å; W90-W96 AromaticContact CZ3-CZ3 3.84Å; W90-W96 HydrophobicContact CZ3-CZ3 3.84Å; W90-W96 AromaticContact NE1-CE2 3.8Å; W90-W96 AromaticContact NE1-CH2 3.95Å; W90-W96 AromaticContact NE1-CZ2 3.78Å; C93-W96 HydrophobicContact CB-CB 4.31Å; C93-W96 WeakPolarHBondContact O-CB 3.31Å; C93-W96 PolarHBondContact O-N 3.45Å; W96-V98 VanDerWaalsContact C-N 3.31Å; W96-V98 PolarHBondContact O-N 2.96Å; W96-L99 PolarHBondContact O-N 3.38Å; W96-A100 PolarHBondContact O-N 3.44Å
97	P	81.1	Confident	77.9	Confident	34 Å²	34	70.2 Å²	70.2	22%	0.221	36%	0.363	C	S	.	.	H	α-helix	trans	-62.7	-37.3	179.8	-24.2	35.6	0	0	0	113	G95 A100 Q101	G95-P97 VanDerWaalsContact C-CD 3.48Å; P97-A100 PolarHBondContact O-N 2.93Å; P97-Q101 VanDerWaalsContact O-CG 3.29Å; P97-Q101 WeakPolarHBondContact O-CG 3.36Å; P97-Q101 PolarHBondContact O-N 3.11Å
98	V	85	Confident	79.7	Confident	36 Å²	36	67.3 Å²	67.3	22%	0.218	35%	0.347	C	S	.	.	H	α-helix	trans	-66.7	-43.3	177.1	178.9	0	0	0	0	109.9	G95 W96 A100 Q101 L102	G95-V98 PolarHBondContact O-N 3.39Å; W96-V98 VanDerWaalsContact C-N 3.31Å; W96-V98 PolarHBondContact O-N 2.96Å; V98-A100 VanDerWaalsContact C-N 3.32Å; V98-A100 PolarHBondContact O-N 3.41Å; V98-Q101 PolarHBondContact O-N 2.83Å; V98-L102 HydrophobicContact CG1-CD1 4.23Å; V98-L102 HydrophobicContact CG1-CG 4.49Å; V98-L102 WeakPolarHBondContact O-CG 3.46Å; V98-L102 PolarHBondContact O-N 3.35Å
99	L	87.6	Confident	81.5	Confident	87 Å²	87	66 Å²	66	46%	0.455	34%	0.341	S	S	.	.	H	α-helix	trans	-61.5	-40.2	176.5	-174.4	63.1	0	0	0	112.1	V79 L83 G95 W96 L102 A103	V79-L99 HydrophobicContact CG1-CG 4.31Å; L83-L99 HydrophobicContact CD1-CB 4.29Å; L83-L99 HydrophobicContact CD1-CD2 4.24Å; L83-L99 HydrophobicContact CD1-CG 4.1Å; L83-L99 HydrophobicContact CD2-CD2 4.24Å; G95-L99 PolarHBondContact O-N 2.94Å; W96-L99 PolarHBondContact O-N 3.38Å; L99-L102 PolarHBondContact O-N 2.95Å; L99-A103 WeakPolarHBondContact O-CB 3.4Å; L99-A103 PolarHBondContact O-N 2.88Å
100	A	89.1	Confident	83.1	Confident	7 Å²	7	57.2 Å²	57.2	6%	0.058	31%	0.31	C	S	.	.	H	α-helix	trans	-61.2	-45.3	174.5	0	0	0	0	0	111.6	L80 L83 W96 P97 V98 L102 A103 V104	L80-A100 HydrophobicContact CD2-CB 4.44Å; L83-A100 HydrophobicContact CD1-CB 3.82Å; W96-A100 PolarHBondContact O-N 3.44Å; P97-A100 PolarHBondContact O-N 2.93Å; V98-A100 VanDerWaalsContact C-N 3.32Å; V98-A100 PolarHBondContact O-N 3.41Å; A100-L102 PolarHBondContact O-N 3.1Å; A100-A103 PolarHBondContact O-N 2.9Å; A100-V104 WeakPolarHBondContact O-CG2 3.45Å; A100-V104 PolarHBondContact O-N 3.13Å
101	Q	92.3	Very high	84.6	Confident	51 Å²	51	54.4 Å²	54.4	24%	0.238	31%	0.306	C	S	.	.	H	α-helix	trans	-64.5	-38.5	177.9	-66.1	-63.6	-43.5	0	0	112.6	P97 V98 V104 G105 L146 T170	P97-Q101 VanDerWaalsContact O-CG 3.29Å; P97-Q101 WeakPolarHBondContact O-CG 3.36Å; P97-Q101 PolarHBondContact O-N 3.11Å; V98-Q101 PolarHBondContact O-N 2.83Å; Q101-V104 PolarHBondContact O-N 3.49Å; Q101-G105 PolarHBondContact O-N 3.28Å; Q101-L146 HydrophobicContact CB-CD1 3.6Å; Q101-L146 HydrophobicContact CB-CD2 4.38Å; Q101-T170 HydrophobicContact CG-CG2 4.05Å
102	L	93.6	Very high	86.3	Confident	32 Å²	32	46 Å²	46	17%	0.168	27%	0.268	C	S	.	.	H	α-helix	trans	-64.3	-40.8	173.9	-68.9	173.6	0	0	0	112	V98 L99 A100 G105 S106 Q143 L146 L147	V98-L102 HydrophobicContact CG1-CD1 4.23Å; V98-L102 HydrophobicContact CG1-CG 4.49Å; V98-L102 WeakPolarHBondContact O-CG 3.46Å; V98-L102 PolarHBondContact O-N 3.35Å; L99-L102 PolarHBondContact O-N 2.95Å; A100-L102 PolarHBondContact O-N 3.1Å; L102-G105 PolarHBondContact O-N 3.4Å; L102-S106 WeakPolarHBondContact O-CB 3.28Å; L102-S106 PolarHBondContact O-N 3.42Å; L102-S106 PolarHBondContact O-OG 2.9Å; L102-Q143 HydrophobicContact CD2-CB 3.95Å; L102-Q143 HydrophobicContact CD2-CG 3.93Å; L102-L146 HydrophobicContact CD2-CB 4.32Å; L102-L146 HydrophobicContact CD2-CD1 4.42Å; L102-L147 HydrophobicContact CD1-CD2 3.89Å; L102-L147 HydrophobicContact CD2-CD2 4.36Å; L102-L147 HydrophobicContact CD2-CG 4.11Å
103	A	94.4	Very high	87.9	Confident	7 Å²	7	40.9 Å²	40.9	6%	0.058	24%	0.241	C	C	.	.	H	α-helix	trans	-66.6	-39	175.9	0	0	0	0	0	111.9	S76 V79 L80 L99 A100 S106 A107	S76-A103 WeakPolarHBondContact CB-O 3.31Å; V79-A103 HydrophobicContact CB-CB 4.29Å; V79-A103 HydrophobicContact CG1-CB 3.93Å; L80-A103 HydrophobicContact CD1-CB 4.45Å; L80-A103 HydrophobicContact CD2-CB 3.87Å; L80-A103 HydrophobicContact CG-CB 3.81Å; L99-A103 WeakPolarHBondContact O-CB 3.4Å; L99-A103 PolarHBondContact O-N 2.88Å; A100-A103 PolarHBondContact O-N 2.9Å; A103-S106 PolarHBondContact O-N 3.04Å; A103-A107 WeakPolarHBondContact O-CB 3.44Å; A103-A107 PolarHBondContact O-N 3.35Å
104	V	94.9	Very high	89.1	Confident	49 Å²	49	38.9 Å²	38.9	30%	0.297	23%	0.227	S	C	.	.	H	α-helix	trans	-60.5	-49	172.1	171	0	0	0	0	110.9	L80 A100 Q101 S106 A107 L108 W174	L80-V104 HydrophobicContact CD1-CG2 4.21Å; L80-V104 HydrophobicContact CD2-CG2 3.93Å; A100-V104 WeakPolarHBondContact O-CG2 3.45Å; A100-V104 PolarHBondContact O-N 3.13Å; Q101-V104 PolarHBondContact O-N 3.49Å; V104-S106 VanDerWaalsContact C-N 3.31Å; V104-S106 PolarHBondContact O-N 3.2Å; V104-A107 PolarHBondContact O-N 3.38Å; V104-L108 HydrophobicContact CG1-CD1 4.01Å; V104-L108 HydrophobicContact CG1-CG 4.44Å; V104-L108 WeakPolarHBondContact O-CG 3.33Å; V104-L108 PolarHBondContact O-N 3.49Å; V104-W174 HydrophobicContact CG1-CH2 4.26Å; V104-W174 HydrophobicContact CG1-CZ2 4.13Å
105	G	94.6	Very high	90.1	Very high	0 Å²	0	36.6 Å²	36.6	0%	0	21%	0.211	C	C	.	.	H	α-helix	trans	-59.6	-41.7	176.5	0	0	0	0	0	112.6	Q101 L102 L108 F109 S139 Q143	Q101-G105 PolarHBondContact O-N 3.28Å; L102-G105 PolarHBondContact O-N 3.4Å; G105-L108 PolarHBondContact O-N 3.37Å; G105-F109 VanDerWaalsContact O-CB 3.25Å; G105-F109 WeakPolarHBondContact O-CB 3.31Å; G105-F109 PolarHBondContact O-N 2.92Å; G105-S139 WeakPolarHBondContact O-CB 3.45Å; G105-Q143 PolarHBondContact O-NE2 3.2Å
106	S	95.9	Very high	90.8	Very high	37 Å²	37	36.3 Å²	36.3	26%	0.259	20%	0.202	S	C	.	.	H	α-helix	trans	-66	-39.2	178.7	-60.1	0	0	0	0	111.9	S76 L102 A103 V104 S110	S76-S106 VanDerWaalsContact OG-CB 3.27Å; S76-S106 WeakPolarHBondContact OG-CB 3.17Å; L102-S106 WeakPolarHBondContact O-CB 3.28Å; L102-S106 PolarHBondContact O-N 3.42Å; L102-S106 PolarHBondContact O-OG 2.9Å; A103-S106 PolarHBondContact O-N 3.04Å; V104-S106 VanDerWaalsContact C-N 3.31Å; V104-S106 PolarHBondContact O-N 3.2Å; S106-S110 WeakPolarHBondContact O-CB 3.43Å; S106-S110 PolarHBondContact O-N 3.29Å; S106-S110 PolarHBondContact O-OG 3.39Å
107	A	95.9	Very high	91.1	Very high	12 Å²	12	35.1 Å²	35.1	10%	0.099	20%	0.198	C	C	.	.	H	α-helix	trans	-64.3	-50.2	174.6	0	0	0	0	0	111.5	S76 A103 V104 F109 S110 I111	S76-A107 PolarHBondContact OG-N 3.38Å; A103-A107 WeakPolarHBondContact O-CB 3.44Å; A103-A107 PolarHBondContact O-N 3.35Å; V104-A107 PolarHBondContact O-N 3.38Å; A107-F109 PolarHBondContact O-N 2.92Å; A107-S110 PolarHBondContact O-N 2.94Å; A107-S110 VanDerWaalsContact O-N 3.13Å; A107-I111 WeakPolarHBondContact O-CD1 3.23Å; A107-I111 VanDerWaalsContact O-CG1 3.24Å; A107-I111 WeakPolarHBondContact O-CG1 3.19Å; A107-I111 PolarHBondContact O-N 3.46Å
108	L	95.8	Very high	90.8	Very high	66 Å²	66	34.6 Å²	34.6	35%	0.346	19%	0.194	S	C	.	.	H	α-helix	trans	-60	-44.5	179.1	-72.1	175	0	0	0	112.1	V104 G105 S110 I111 V112 V135 S139 W174	V104-L108 HydrophobicContact CG1-CD1 4.01Å; V104-L108 HydrophobicContact CG1-CG 4.44Å; V104-L108 WeakPolarHBondContact O-CG 3.33Å; V104-L108 PolarHBondContact O-N 3.49Å; G105-L108 PolarHBondContact O-N 3.37Å; L108-S110 VanDerWaalsContact C-N 3.33Å; L108-S110 PolarHBondContact O-N 2.99Å; L108-I111 PolarHBondContact O-N 3.46Å; L108-V112 PolarHBondContact O-N 3.43Å; L108-V135 HydrophobicContact CB-CG1 4.06Å; L108-S139 VanDerWaalsContact CB-OG 3.31Å; L108-S139 WeakPolarHBondContact CB-OG 3.44Å; L108-W174 HydrophobicContact CD1-CH2 3.86Å; L108-W174 HydrophobicContact CD1-CZ3 4.02Å
109	F	94.6	Very high	90.1	Very high	70 Å²	70	34 Å²	34	31%	0.307	20%	0.196	S	C	.	.	H	α-helix	trans	-56.9	-47.1	173.2	-176.1	-78.5	0	0	0	111.1	G105 A107 V112 V113 W136 A140	G105-F109 VanDerWaalsContact O-CB 3.25Å; G105-F109 WeakPolarHBondContact O-CB 3.31Å; G105-F109 PolarHBondContact O-N 2.92Å; A107-F109 PolarHBondContact O-N 2.92Å; F109-V112 WeakPolarHBondContact O-CG1 3.38Å; F109-V112 PolarHBondContact O-N 2.71Å; F109-V113 HydrophobicContact CD1-CG2 4.11Å; F109-V113 HydrophobicContact CE1-CG2 4.01Å; F109-V113 VanDerWaalsContact O-CG2 3.31Å; F109-V113 WeakPolarHBondContact O-CG2 3.25Å; F109-V113 PolarHBondContact O-N 2.61Å; F109-W136 AromaticContact CD2-CD1 3.27Å; F109-W136 HydrophobicContact CD2-CG 4.43Å; F109-W136 AromaticContact CD2-NE1 3.52Å; F109-W136 AromaticContact CE1-NE1 3.59Å; F109-W136 AromaticContact CE2-CD1 3.18Å; F109-W136 AromaticContact CE2-CE2 3.99Å; F109-W136 HydrophobicContact CE2-CG 4.34Å; F109-W136 AromaticContact CE2-NE1 2.9Å; F109-W136 AromaticContact CG-CD1 3.82Å; F109-W136 AromaticContact CZ-CD1 3.64Å; F109-W136 AromaticContact CZ-CE2 4Å; F109-W136 AromaticContact CZ-NE1 2.94Å; F109-A140 HydrophobicContact CD2-CB 4.44Å; F109-A140 HydrophobicContact CE2-CB 4.36Å
110	S	95.5	Very high	89.2	Confident	13 Å²	13	33.1 Å²	33.1	9%	0.091	19%	0.191	C	C	.	.	H	α-helix	trans	-69	-36.8	-177.1	-57	0	0	0	0	112.7	S69 G72 S106 A107 L108 V112 V113 P114	S69-S110 VanDerWaalsContact CB-O 3.28Å; S69-S110 WeakPolarHBondContact CB-O 3.29Å; S69-S110 PolarHBondContact OG-O 3.22Å; G72-S110 WeakPolarHBondContact CA-OG 3.2Å; S106-S110 WeakPolarHBondContact O-CB 3.43Å; S106-S110 PolarHBondContact O-N 3.29Å; S106-S110 PolarHBondContact O-OG 3.39Å; A107-S110 PolarHBondContact O-N 2.94Å; A107-S110 VanDerWaalsContact O-N 3.13Å; L108-S110 VanDerWaalsContact C-N 3.33Å; L108-S110 PolarHBondContact O-N 2.99Å; S110-V112 VanDerWaalsContact C-N 3.29Å; S110-V112 PolarHBondContact O-N 3.5Å; S110-V113 PolarHBondContact O-N 3.36Å; S110-P114 WeakPolarHBondContact O-CD 3.27Å
111	I	94	Very high	87.7	Confident	97 Å²	97	37.3 Å²	37.3	50%	0.497	24%	0.235	S	C	.	.	H	α-helix	trans	-62.7	-36.2	179.2	-72	163.1	0	0	0	111.8	I73 A107 L108 P114	I73-I111 HydrophobicContact CD1-CG1 3.87Å; I73-I111 HydrophobicContact CG1-CG1 3.89Å; A107-I111 WeakPolarHBondContact O-CD1 3.23Å; A107-I111 VanDerWaalsContact O-CG1 3.24Å; A107-I111 WeakPolarHBondContact O-CG1 3.19Å; A107-I111 PolarHBondContact O-N 3.46Å; L108-I111 PolarHBondContact O-N 3.46Å; I111-P114 WeakPolarHBondContact O-CD 3.31Å
112	V	93.2	Very high	86.4	Confident	12 Å²	12	38.1 Å²	38.1	7%	0.073	25%	0.246	C	C	.	.	H	α-helix	trans	-88.7	-16.3	-173.7	78.3	0	0	0	0	113.7	L108 F109 S110 V115 L116 G132 V135 W136	L108-V112 PolarHBondContact O-N 3.43Å; F109-V112 WeakPolarHBondContact O-CG1 3.38Å; F109-V112 PolarHBondContact O-N 2.71Å; S110-V112 VanDerWaalsContact C-N 3.29Å; S110-V112 PolarHBondContact O-N 3.5Å; V112-V115 HydrophobicContact CG2-CB 4.37Å; V112-V115 WeakPolarHBondContact O-CB 3.4Å; V112-V115 PolarHBondContact O-N 3.38Å; V112-L116 PolarHBondContact O-N 2.67Å; V112-G132 WeakPolarHBondContact CG2-O 3.32Å; V112-V135 HydrophobicContact CB-CB 4.39Å; V112-V135 HydrophobicContact CB-CG1 4.14Å; V112-V135 HydrophobicContact CG1-CB 4.35Å; V112-V135 HydrophobicContact CG1-CG1 4.08Å; V112-V135 HydrophobicContact CG2-CB 4.29Å; V112-W136 HydrophobicContact CG1-CB 3.74Å; V112-W136 HydrophobicContact CG1-CG 4.32Å
113	V	90.9	Very high	85.1	Confident	16 Å²	16	42.9 Å²	42.9	10%	0.097	28%	0.277	C	S	.	.	H	α-helix	trans	-52.8	-48.4	178.7	160.7	0	0	0	0	113.1	F65 F109 S110 V115 L116 A117	F65-V113 HydrophobicContact CB-CG1 3.88Å; F65-V113 HydrophobicContact CD1-CG1 3.6Å; F65-V113 HydrophobicContact CG-CG1 4.2Å; F109-V113 HydrophobicContact CD1-CG2 4.11Å; F109-V113 HydrophobicContact CE1-CG2 4.01Å; F109-V113 VanDerWaalsContact O-CG2 3.31Å; F109-V113 WeakPolarHBondContact O-CG2 3.25Å; F109-V113 PolarHBondContact O-N 2.61Å; S110-V113 PolarHBondContact O-N 3.36Å; V113-V115 VanDerWaalsContact C-N 3.27Å; V113-V115 PolarHBondContact O-N 2.87Å; V113-L116 PolarHBondContact O-N 2.99Å; V113-L116 VanDerWaalsContact O-N 3.13Å; V113-A117 WeakPolarHBondContact O-CB 3.36Å; V113-A117 PolarHBondContact O-N 2.93Å
114	P	87.7	Confident	84.3	Confident	27 Å²	27	43.7 Å²	43.7	18%	0.175	28%	0.279	C	S	.	.	H	α-helix	trans	-60.2	-36.9	176.8	-26.7	37.3	0	0	0	112.9	I66 S69 S110 I111 L116 A117 L120	I66-P114 HydrophobicContact CD1-CB 3.72Å; I66-P114 HydrophobicContact CD1-CG 3.97Å; S69-P114 WeakPolarHBondContact OG-CD 3.39Å; S69-P114 VanDerWaalsContact OG-CG 3.31Å; S69-P114 WeakPolarHBondContact OG-CG 3.38Å; S110-P114 WeakPolarHBondContact O-CD 3.27Å; I111-P114 WeakPolarHBondContact O-CD 3.31Å; P114-L116 PolarHBondContact O-N 3.45Å; P114-A117 PolarHBondContact O-N 2.98Å; P114-L120 WeakPolarHBondContact O-CD1 3.29Å
115	V	86.1	Confident	83.8	Confident	57 Å²	57	44.1 Å²	44.1	35%	0.345	28%	0.284	S	S	.	.	H	α-helix	trans	-62.3	-36.5	178.8	-178.5	0	0	0	0	110.4	V112 V113 R124	V112-V115 HydrophobicContact CG2-CB 4.37Å; V112-V115 WeakPolarHBondContact O-CB 3.4Å; V112-V115 PolarHBondContact O-N 3.38Å; V113-V115 VanDerWaalsContact C-N 3.27Å; V113-V115 PolarHBondContact O-N 2.87Å; V115-R124 PolarHBondContact O-NE 3.47Å; V115-R124 PolarHBondContact O-NH2 3.5Å; V115-R124 VanDerWaalsContact O-NH2 3.08Å
116	L	86.3	Confident	83.4	Confident	27 Å²	27	47.1 Å²	47.1	14%	0.141	31%	0.305	C	S	.	.	H	α-helix	trans	-89.1	-11.8	-179.7	-61.5	177.2	0	0	0	113.9	V112 V113 P114 Y133 W136 C195	V112-L116 PolarHBondContact O-N 2.67Å; V113-L116 PolarHBondContact O-N 2.99Å; V113-L116 VanDerWaalsContact O-N 3.13Å; P114-L116 PolarHBondContact O-N 3.45Å; L116-Y133 HydrophobicContact CD1-CD1 4.38Å; L116-Y133 HydrophobicContact CD2-CD2 4.34Å; L116-Y133 HydrophobicContact CD2-CE2 4.35Å; L116-Y133 HydrophobicContact CD2-CG 4.42Å; L116-W136 HydrophobicContact CD1-CB 3.72Å; L116-W136 HydrophobicContact CD1-CD2 3.77Å; L116-W136 HydrophobicContact CD1-CE3 3.59Å; L116-W136 HydrophobicContact CD1-CG 3.84Å; L116-W136 HydrophobicContact CD1-CZ3 4.45Å; L116-C195 HydrophobicContact CD2-CB 4.01Å
117	A	84.4	Confident	83	Confident	1 Å²	1	48.8 Å²	48.8	1%	0.008	32%	0.321	C	S	.	.			trans	-69.4	139.5	-173.8	0	0	0	0	0	112.8	L62 F65 V113 P114 L120 R124	L62-A117 HydrophobicContact CD1-CB 3.95Å; F65-A117 HydrophobicContact CB-CB 3.64Å; F65-A117 HydrophobicContact CD1-CB 4.47Å; F65-A117 HydrophobicContact CD2-CB 3.79Å; F65-A117 HydrophobicContact CG-CB 3.73Å; V113-A117 WeakPolarHBondContact O-CB 3.36Å; V113-A117 PolarHBondContact O-N 2.93Å; P114-A117 PolarHBondContact O-N 2.98Å; A117-L120 HydrophobicContact CB-CD1 4.47Å; A117-R124 PolarHBondContact O-NH2 3.46Å
118	P	75	Confident	82.6	Confident	22 Å²	22	52.7 Å²	52.7	14%	0.143	34%	0.339	C	S	.	.	T	Hydrogen-bonded Turn	trans	-62.9	158.1	169	28.5	-33.6	0	0	0	111.2	L62 F65 L194	L62-P118 WeakPolarHBondContact CD1-O 3.42Å; F65-P118 HydrophobicContact CE2-CG 4.09Å; P118-L194 HydrophobicContact CB-CD2 3.72Å
119	G	70.8	Confident	82.3	Confident	25 Å²	25	49.6 Å²	49.6	26%	0.258	32%	0.323	S	S	.	.	T	Hydrogen-bonded Turn	trans	91.2	-6.2	174.3	0	0	0	0	0	117.9	D59 G121	D59-G119 WeakPolarHBondContact OD1-CA 3.49Å; D59-G119 PolarHBondContact OD1-N 3.21Å; G119-G121 PolarHBondContact O-N 3.23Å
120	L	68	Low	82.1	Confident	67 Å²	67	47.6 Å²	47.6	35%	0.351	32%	0.318	S	S	.	.			trans	-77.2	103.3	164.4	-77.5	109.2	0	0	0	108.7	L62 P114 A117 S122 R124	L62-L120 HydrophobicContact CD1-CD1 3.45Å; L62-L120 VanDerWaalsContact CD1-CD1 3.45Å; L62-L120 HydrophobicContact CD1-CG 4.04Å; P114-L120 WeakPolarHBondContact O-CD1 3.29Å; A117-L120 HydrophobicContact CB-CD1 4.47Å; L120-S122 PolarHBondContact O-N 3.2Å; L120-R124 VanDerWaalsContact CD1-NH2 3.34Å
121	G	58.6	Low	82	Confident	95 Å²	95	52 Å²	52	98%	0.979	34%	0.34	S	S	*	.			trans	-65	25.7	-176.8	0	0	0	0	0	116.8	G119	G119-G121 PolarHBondContact O-N 3.23Å
122	S	64.5	Low	81.9	Confident	69 Å²	69	47.5 Å²	47.5	48%	0.483	32%	0.317	S	S	.	.	S	Bend	trans	-107.8	139.8	174.1	74.4	0	0	0	0	111.2	L120 R124	L120-S122 PolarHBondContact O-N 3.2Å; S122-R124 PolarHBondContact O-N 3.2Å; S122-R124 VanDerWaalsContact O-N 3.1Å
123	T	65.4	Low	81.8	Confident	132 Å²	132	48.4 Å²	48.4	81%	0.81	32%	0.32	S	S	*	.			trans	-60.2	111.3	169.5	51.4	0	0	0	0	110.6
124	R	78.2	Confident	82	Confident	24 Å²	24	49.5 Å²	49.5	9%	0.091	33%	0.327	C	S	.	.			trans	-78.3	143.4	174	-68.6	175.7	-179.8	104.8	-9.8	110.8	V115 A117 L120 S122 A190 G193 C195	V115-R124 PolarHBondContact O-NE 3.47Å; V115-R124 PolarHBondContact O-NH2 3.5Å; V115-R124 VanDerWaalsContact O-NH2 3.08Å; A117-R124 PolarHBondContact O-NH2 3.46Å; L120-R124 VanDerWaalsContact CD1-NH2 3.34Å; S122-R124 PolarHBondContact O-N 3.2Å; S122-R124 VanDerWaalsContact O-N 3.1Å; R124-A190 HydrophobicContact CB-CB 4.39Å; R124-A190 WeakPolarHBondContact O-CB 3.3Å; R124-G193 PolarHBondContact NH1-O 3.09Å; R124-C195 WeakPolarHBondContact CD-SG 3.36Å
125	S	85.3	Confident	82.3	Confident	58 Å²	58	50.2 Å²	50.2	41%	0.406	33%	0.331	S	S	.	.			trans	-77.3	145.7	169	69	0	0	0	0	110.2	A127 L128 C129	S125-A127 PolarHBondContact O-N 3.38Å; S125-L128 PolarHBondContact O-N 3.28Å; S125-L128 WeakPolarHBondContact OG-CB 3.32Å; S125-L128 WeakPolarHBondContact OG-CD1 3.33Å; S125-L128 VanDerWaalsContact OG-CG 3.25Å; S125-L128 WeakPolarHBondContact OG-CG 3.26Å; S125-L128 PolarHBondContact OG-N 3Å; S125-C129 PolarHBondContact O-N 3.46Å; S125-C129 VanDerWaalsContact O-N 3.14Å
126	S	85.6	Confident	82.7	Confident	63 Å²	63	51.1 Å²	51.1	44%	0.441	33%	0.329	S	S	.	.	H	α-helix	trans	-55.5	-37.4	175.8	-55.1	0	0	0	0	111.6	L128 C129 S130	S126-L128 PolarHBondContact O-N 3.43Å; S126-C129 PolarHBondContact O-N 3.39Å; S126-S130 PolarHBondContact O-N 2.87Å; S126-S130 PolarHBondContact O-OG 3.3Å
127	A	86.9	Confident	83.1	Confident	72 Å²	72	52.6 Å²	52.6	60%	0.595	33%	0.333	S	S	*	.	H	α-helix	trans	-61	-40.1	176.4	0	0	0	0	0	113.2	S125 S130 L131	S125-A127 PolarHBondContact O-N 3.38Å; A127-S130 PolarHBondContact O-N 3.42Å; A127-L131 VanDerWaalsContact O-CB 3.31Å; A127-L131 WeakPolarHBondContact O-CB 3.34Å; A127-L131 PolarHBondContact O-N 2.91Å
128	L	88.6	Confident	83.6	Confident	94 Å²	94	52.9 Å²	52.9	49%	0.492	34%	0.336	S	S	.	.	H	α-helix	trans	-67.6	-37.9	175.4	-75.6	171.5	0	0	0	111.6	S125 S126 G132	S125-L128 PolarHBondContact O-N 3.28Å; S125-L128 WeakPolarHBondContact OG-CB 3.32Å; S125-L128 WeakPolarHBondContact OG-CD1 3.33Å; S125-L128 VanDerWaalsContact OG-CG 3.25Å; S125-L128 WeakPolarHBondContact OG-CG 3.26Å; S125-L128 PolarHBondContact OG-N 3Å; S126-L128 PolarHBondContact O-N 3.43Å; L128-G132 WeakPolarHBondContact O-CA 3.3Å; L128-G132 PolarHBondContact O-N 2.98Å
129	C	89.1	Confident	84.7	Confident	0 Å²	0	52 Å²	52	0%	0	33%	0.33	C	S	.	.	H	α-helix	trans	-66.1	-44.8	174.7	-70	0	0	0	0	111.9	S125 S126 G132 Y133 C195	S125-C129 PolarHBondContact O-N 3.46Å; S125-C129 VanDerWaalsContact O-N 3.14Å; S126-C129 PolarHBondContact O-N 3.39Å; C129-G132 WeakPolarHBondContact O-CA 3.39Å; C129-G132 PolarHBondContact O-N 3.05Å; C129-G132 VanDerWaalsContact O-N 3.12Å; C129-Y133 WeakPolarHBondContact O-CD2 3.28Å; C129-Y133 PolarHBondContact O-N 2.86Å; C129-C195 WeakPolarHBondContact CA-SG 3.34Å; C129-C195 HydrophobicContact CB-CB 3.66Å; C129-C195 WeakPolarHBondContact CB-SG 3.42Å; C129-C195 WeakPolarHBondContact SG-CA 3.18Å; C129-C195 WeakPolarHBondContact SG-CB 3.48Å; C129-C195 CovalentContact SG-SG 2.04Å; C129-C195 PolarHBondContact SG-SG 3.33Å
130	S	90.7	Very high	85.8	Confident	29 Å²	29	51.6 Å²	51.6	20%	0.203	33%	0.325	C	S	.	.	H	α-helix	trans	-64	-44.2	177.3	-52.3	0	0	0	0	112.5	S126 A127 G132 Y133 C134 T185 S188	S126-S130 PolarHBondContact O-N 2.87Å; S126-S130 PolarHBondContact O-OG 3.3Å; A127-S130 PolarHBondContact O-N 3.42Å; S130-G132 PolarHBondContact O-N 3.34Å; S130-Y133 PolarHBondContact O-N 3.47Å; S130-C134 VanDerWaalsContact O-CB 3.29Å; S130-C134 WeakPolarHBondContact O-CB 3.46Å; S130-C134 PolarHBondContact O-N 3.41Å; S130-T185 PolarHBondContact OG-O 2.79Å; S130-S188 WeakPolarHBondContact CA-OG 3.47Å; S130-S188 WeakPolarHBondContact CB-OG 3.35Å; S130-S188 PolarHBondContact OG-OG 2.8Å
131	L	92.1	Very high	87.2	Confident	106 Å²	106	48.4 Å²	48.4	56%	0.555	31%	0.308	S	S	*	.	H	α-helix	trans	-61.7	-39.7	172.2	-175.4	67.6	0	0	0	110.7	A127 C134 V135	A127-L131 VanDerWaalsContact O-CB 3.31Å; A127-L131 WeakPolarHBondContact O-CB 3.34Å; A127-L131 PolarHBondContact O-N 2.91Å; L131-C134 WeakPolarHBondContact O-CB 3.43Å; L131-C134 PolarHBondContact O-N 3.49Å; L131-V135 HydrophobicContact CD1-CG2 4.36Å; L131-V135 HydrophobicContact CG-CG2 4.45Å; L131-V135 WeakPolarHBondContact O-CG2 3.02Å; L131-V135 PolarHBondContact O-N 2.79Å
132	G	92.1	Very high	89	Confident	2 Å²	2	43.9 Å²	43.9	2%	0.021	26%	0.261	C	S	.	.	H	α-helix	trans	-55.8	-56	177.5	0	0	0	0	0	112	V112 L128 C129 S130 C134 V135 W136	V112-G132 WeakPolarHBondContact CG2-O 3.32Å; L128-G132 WeakPolarHBondContact O-CA 3.3Å; L128-G132 PolarHBondContact O-N 2.98Å; C129-G132 WeakPolarHBondContact O-CA 3.39Å; C129-G132 PolarHBondContact O-N 3.05Å; C129-G132 VanDerWaalsContact O-N 3.12Å; S130-G132 PolarHBondContact O-N 3.34Å; G132-C134 VanDerWaalsContact C-N 3.34Å; G132-C134 PolarHBondContact O-N 2.92Å; G132-V135 PolarHBondContact O-N 2.92Å; G132-W136 VanDerWaalsContact O-CB 3.24Å; G132-W136 WeakPolarHBondContact O-CB 3.48Å; G132-W136 PolarHBondContact O-N 2.89Å
133	Y	91.6	Very high	90.4	Very high	30 Å²	30	42.5 Å²	42.5	12%	0.118	25%	0.247	C	C	.	.	H	α-helix	trans	-63.4	-37.4	176.4	-76.1	-63.6	0	0	0	112.9	L116 C129 S130 W136 Y137 V184 S188 C195	L116-Y133 HydrophobicContact CD1-CD1 4.38Å; L116-Y133 HydrophobicContact CD2-CD2 4.34Å; L116-Y133 HydrophobicContact CD2-CE2 4.35Å; L116-Y133 HydrophobicContact CD2-CG 4.42Å; C129-Y133 WeakPolarHBondContact O-CD2 3.28Å; C129-Y133 PolarHBondContact O-N 2.86Å; S130-Y133 PolarHBondContact O-N 3.47Å; Y133-W136 AromaticContact CD1-CE3 3.84Å; Y133-W136 HydrophobicContact CD1-CE3 3.84Å; Y133-W136 HydrophobicContact CD1-CZ3 4.23Å; Y133-W136 HydrophobicContact CE1-CE3 4.01Å; Y133-W136 AromaticContact CE1-CZ3 3.96Å; Y133-W136 HydrophobicContact CE1-CZ3 3.96Å; Y133-W136 PolarHBondContact O-N 3.44Å; Y133-Y137 HydrophobicContact CD1-CD2 4.04Å; Y133-Y137 AromaticContact CD1-CE2 3.7Å; Y133-Y137 HydrophobicContact CD1-CE2 3.7Å; Y133-Y137 HydrophobicContact CE1-CE2 4.3Å; Y133-Y137 WeakPolarHBondContact O-CB 3.42Å; Y133-Y137 PolarHBondContact O-N 3.38Å; Y133-V184 HydrophobicContact CD1-CG2 4.31Å; Y133-V184 HydrophobicContact CG-CG2 4.23Å; Y133-S188 VanDerWaalsContact CD2-CB 3.44Å; Y133-C195 HydrophobicContact CE2-CB 3.89Å; Y133-C195 PolarHBondContact OH-O 2.88Å
134	C	94.3	Very high	91.8	Very high	39 Å²	39	37.1 Å²	37.1	26%	0.264	22%	0.216	S	C	.	.	H	α-helix	trans	-56.3	-54.7	174.7	-172.5	0	0	0	0	110.9	S130 L131 G132 W136 G138 T185	S130-C134 VanDerWaalsContact O-CB 3.29Å; S130-C134 WeakPolarHBondContact O-CB 3.46Å; S130-C134 PolarHBondContact O-N 3.41Å; L131-C134 WeakPolarHBondContact O-CB 3.43Å; L131-C134 PolarHBondContact O-N 3.49Å; G132-C134 VanDerWaalsContact C-N 3.34Å; G132-C134 PolarHBondContact O-N 2.92Å; C134-W136 VanDerWaalsContact C-N 3.34Å; C134-W136 PolarHBondContact O-N 2.98Å; C134-G138 VanDerWaalsContact O-CA 3.3Å; C134-G138 WeakPolarHBondContact O-CA 3.37Å; C134-G138 PolarHBondContact O-N 3.3Å; C134-T185 HydrophobicContact CB-CG2 3.42Å; C134-T185 VanDerWaalsContact CB-CG2 3.42Å
135	V	95.5	Very high	92.6	Very high	42 Å²	42	37.2 Å²	37.2	26%	0.255	22%	0.218	S	C	.	.	H	α-helix	trans	-66.2	-40.6	-178.7	175.5	0	0	0	0	110.6	L108 V112 L131 G132 S139	L108-V135 HydrophobicContact CB-CG1 4.06Å; V112-V135 HydrophobicContact CB-CB 4.39Å; V112-V135 HydrophobicContact CB-CG1 4.14Å; V112-V135 HydrophobicContact CG1-CB 4.35Å; V112-V135 HydrophobicContact CG1-CG1 4.08Å; V112-V135 HydrophobicContact CG2-CB 4.29Å; L131-V135 HydrophobicContact CD1-CG2 4.36Å; L131-V135 HydrophobicContact CG-CG2 4.45Å; L131-V135 WeakPolarHBondContact O-CG2 3.02Å; L131-V135 PolarHBondContact O-N 2.79Å; G132-V135 PolarHBondContact O-N 2.92Å; V135-S139 WeakPolarHBondContact O-CB 3.41Å; V135-S139 PolarHBondContact O-N 2.77Å; V135-S139 PolarHBondContact O-OG 3.36Å
136	W	94.1	Very high	92.9	Very high	77 Å²	77	34.9 Å²	34.9	29%	0.292	20%	0.201	S	C	.	.	H	α-helix	trans	-64.7	-59.5	-177.5	-171.9	39	0	0	0	112.3	F109 V112 L116 G132 Y133 C134 S139 A140	F109-W136 AromaticContact CD2-CD1 3.27Å; F109-W136 HydrophobicContact CD2-CG 4.43Å; F109-W136 AromaticContact CD2-NE1 3.52Å; F109-W136 AromaticContact CE1-NE1 3.59Å; F109-W136 AromaticContact CE2-CD1 3.18Å; F109-W136 AromaticContact CE2-CE2 3.99Å; F109-W136 HydrophobicContact CE2-CG 4.34Å; F109-W136 AromaticContact CE2-NE1 2.9Å; F109-W136 AromaticContact CG-CD1 3.82Å; F109-W136 AromaticContact CZ-CD1 3.64Å; F109-W136 AromaticContact CZ-CE2 4Å; F109-W136 AromaticContact CZ-NE1 2.94Å; V112-W136 HydrophobicContact CG1-CB 3.74Å; V112-W136 HydrophobicContact CG1-CG 4.32Å; L116-W136 HydrophobicContact CD1-CB 3.72Å; L116-W136 HydrophobicContact CD1-CD2 3.77Å; L116-W136 HydrophobicContact CD1-CE3 3.59Å; L116-W136 HydrophobicContact CD1-CG 3.84Å; L116-W136 HydrophobicContact CD1-CZ3 4.45Å; G132-W136 VanDerWaalsContact O-CB 3.24Å; G132-W136 WeakPolarHBondContact O-CB 3.48Å; G132-W136 PolarHBondContact O-N 2.89Å; Y133-W136 AromaticContact CD1-CE3 3.84Å; Y133-W136 HydrophobicContact CD1-CE3 3.84Å; Y133-W136 HydrophobicContact CD1-CZ3 4.23Å; Y133-W136 HydrophobicContact CE1-CE3 4.01Å; Y133-W136 AromaticContact CE1-CZ3 3.96Å; Y133-W136 HydrophobicContact CE1-CZ3 3.96Å; Y133-W136 PolarHBondContact O-N 3.44Å; C134-W136 VanDerWaalsContact C-N 3.34Å; C134-W136 PolarHBondContact O-N 2.98Å; W136-S139 PolarHBondContact O-N 3.39Å; W136-A140 PolarHBondContact O-N 2.83Å
137	Y	94.6	Very high	93.2	Very high	57 Å²	57	36.4 Å²	36.4	22%	0.224	20%	0.204	C	C	.	.	H	α-helix	trans	-68.6	-36.4	178.9	-79.1	-74.9	0	0	0	112	Y133 S139 A140 F141 V184 H210	Y133-Y137 HydrophobicContact CD1-CD2 4.04Å; Y133-Y137 AromaticContact CD1-CE2 3.7Å; Y133-Y137 HydrophobicContact CD1-CE2 3.7Å; Y133-Y137 HydrophobicContact CE1-CE2 4.3Å; Y133-Y137 WeakPolarHBondContact O-CB 3.42Å; Y133-Y137 PolarHBondContact O-N 3.38Å; Y137-S139 VanDerWaalsContact C-N 3.34Å; Y137-S139 PolarHBondContact O-N 2.88Å; Y137-A140 PolarHBondContact O-N 3.04Å; Y137-F141 HydrophobicContact CD1-CE2 4.47Å; Y137-F141 WeakPolarHBondContact O-CB 3.35Å; Y137-F141 WeakPolarHBondContact O-CD2 3.29Å; Y137-F141 WeakPolarHBondContact O-CG 3.09Å; Y137-F141 PolarHBondContact O-N 3.49Å; Y137-V184 HydrophobicContact CD2-CB 4.42Å; Y137-V184 HydrophobicContact CD2-CG1 3.87Å; Y137-V184 HydrophobicContact CD2-CG2 3.9Å; Y137-V184 HydrophobicContact CE2-CG2 3.78Å; Y137-V184 HydrophobicContact CG-CG1 4.27Å; Y137-H210 AromaticContact CD1-CE1 3.6Å; Y137-H210 AromaticContact CD1-NE2 3.8Å; Y137-H210 AromaticContact CE1-CE1 3.69Å; Y137-H210 AromaticContact CE1-NE2 3.38Å; Y137-H210 WeakPolarHBondContact CE1-NE2 3.46Å; Y137-H210 AromaticContact CE2-NE2 3.87Å; Y137-H210 AromaticContact CG-CE1 3.84Å; Y137-H210 AromaticContact CZ-NE2 3.42Å
138	G	96	Very high	93.3	Very high	8 Å²	8	33.2 Å²	33.2	8%	0.082	18%	0.178	C	C	.	.	H	α-helix	trans	-62.3	-43.8	179.2	0	0	0	0	0	111.4	C134 A140 F141 A142 A177	C134-G138 VanDerWaalsContact O-CA 3.3Å; C134-G138 WeakPolarHBondContact O-CA 3.37Å; C134-G138 PolarHBondContact O-N 3.3Å; G138-A140 VanDerWaalsContact C-N 3.35Å; G138-A140 PolarHBondContact O-N 3.23Å; G138-F141 PolarHBondContact O-N 2.96Å; G138-A142 VanDerWaalsContact O-CB 3.29Å; G138-A142 WeakPolarHBondContact O-CB 3.47Å; G138-A142 PolarHBondContact O-N 2.85Å; G138-A177 WeakPolarHBondContact O-CB 3.41Å
139	S	96.1	Very high	93.3	Very high	2 Å²	2	30.2 Å²	30.2	1%	0.014	17%	0.165	C	C	.	.	H	α-helix	trans	-63.3	-40.6	174.9	-59.6	0	0	0	0	112.1	G105 L108 V135 W136 Y137 Q143	G105-S139 WeakPolarHBondContact O-CB 3.45Å; L108-S139 VanDerWaalsContact CB-OG 3.31Å; L108-S139 WeakPolarHBondContact CB-OG 3.44Å; V135-S139 WeakPolarHBondContact O-CB 3.41Å; V135-S139 PolarHBondContact O-N 2.77Å; V135-S139 PolarHBondContact O-OG 3.36Å; W136-S139 PolarHBondContact O-N 3.39Å; Y137-S139 VanDerWaalsContact C-N 3.34Å; Y137-S139 PolarHBondContact O-N 2.88Å; S139-Q143 VanDerWaalsContact O-CG 3.23Å; S139-Q143 WeakPolarHBondContact O-CG 3.24Å; S139-Q143 PolarHBondContact O-N 3.49Å; S139-Q143 VanDerWaalsContact O-N 3.09Å; S139-Q143 PolarHBondContact O-NE2 3.33Å
140	A	95.5	Very high	93.1	Very high	18 Å²	18	34.3 Å²	34.3	15%	0.149	18%	0.184	C	C	.	.	H	α-helix	trans	-67.6	-45	178.7	0	0	0	0	0	112.2	F109 W136 Y137 G138 Q143 A144 F218	F109-A140 HydrophobicContact CD2-CB 4.44Å; F109-A140 HydrophobicContact CE2-CB 4.36Å; W136-A140 PolarHBondContact O-N 2.83Å; Y137-A140 PolarHBondContact O-N 3.04Å; G138-A140 VanDerWaalsContact C-N 3.35Å; G138-A140 PolarHBondContact O-N 3.23Å; A140-Q143 PolarHBondContact O-N 3.33Å; A140-A144 PolarHBondContact O-N 3.04Å; A140-F218 HydrophobicContact CB-CE1 4.13Å; A140-F218 HydrophobicContact CB-CZ 3.69Å
141	F	96.3	Very high	92.8	Very high	0 Å²	0	36.2 Å²	36.2	0%	0	20%	0.201	C	C	.	.	H	α-helix	trans	-62.1	-44.8	175.2	-74.4	-51.4	0	0	0	111.7	Y137 G138 Q143 A144 L145 A177 L180 T181 A213 I217 F218	Y137-F141 HydrophobicContact CD1-CE2 4.47Å; Y137-F141 WeakPolarHBondContact O-CB 3.35Å; Y137-F141 WeakPolarHBondContact O-CD2 3.29Å; Y137-F141 WeakPolarHBondContact O-CG 3.09Å; Y137-F141 PolarHBondContact O-N 3.49Å; G138-F141 PolarHBondContact O-N 2.96Å; F141-Q143 VanDerWaalsContact C-N 3.33Å; F141-Q143 PolarHBondContact O-N 2.96Å; F141-A144 PolarHBondContact O-N 3.26Å; F141-L145 WeakPolarHBondContact O-CB 3.46Å; F141-L145 VanDerWaalsContact O-CG 3.26Å; F141-L145 WeakPolarHBondContact O-CG 3.29Å; F141-L145 PolarHBondContact O-N 3.03Å; F141-A177 HydrophobicContact CB-CB 3.92Å; F141-L180 HydrophobicContact CB-CD1 4.45Å; F141-L180 HydrophobicContact CD1-CD1 4.26Å; F141-L180 HydrophobicContact CD2-CB 3.82Å; F141-L180 HydrophobicContact CE2-CB 3.91Å; F141-L180 HydrophobicContact CG-CB 4.26Å; F141-L180 HydrophobicContact CG-CD1 4.23Å; F141-L180 HydrophobicContact CZ-CB 4.41Å; F141-T181 HydrophobicContact CD2-CG2 4.13Å; F141-T181 HydrophobicContact CE2-CG2 4.45Å; F141-A213 HydrophobicContact CZ-CB 4.35Å; F141-I217 HydrophobicContact CD1-CB 4.02Å; F141-I217 HydrophobicContact CD1-CG1 4.14Å; F141-I217 HydrophobicContact CD1-CG2 3.89Å; F141-I217 HydrophobicContact CE1-CB 4.12Å; F141-I217 HydrophobicContact CE1-CG1 4.22Å; F141-I217 HydrophobicContact CE1-CG2 4.47Å; F141-F218 AromaticContact CD1-CE2 3.92Å; F141-F218 HydrophobicContact CD1-CE2 3.92Å; F141-F218 AromaticContact CD1-CZ 3.77Å; F141-F218 HydrophobicContact CD1-CZ 3.77Å; F141-F218 HydrophobicContact CE1-CD2 4.39Å; F141-F218 AromaticContact CE1-CE2 3.63Å; F141-F218 HydrophobicContact CE1-CE2 3.63Å; F141-F218 AromaticContact CE1-CZ 3.99Å; F141-F218 HydrophobicContact CE1-CZ 3.99Å; F141-F218 HydrophobicContact CG-CZ 4.41Å; F141-F218 HydrophobicContact CZ-CE2 4.3Å
142	A	96.1	Very high	92.4	Very high	0 Å²	0	33.9 Å²	33.9	0%	0	19%	0.194	C	C	.	.	H	α-helix	trans	-58.2	-46.2	177.6	0	0	0	0	0	111.2	G138 L145 L146 W174 A177	G138-A142 VanDerWaalsContact O-CB 3.29Å; G138-A142 WeakPolarHBondContact O-CB 3.47Å; G138-A142 PolarHBondContact O-N 2.85Å; A142-L145 PolarHBondContact O-N 3.12Å; A142-L146 VanDerWaalsContact O-CB 3.3Å; A142-L146 WeakPolarHBondContact O-CB 3.47Å; A142-L146 WeakPolarHBondContact O-CD1 3.49Å; A142-L146 WeakPolarHBondContact O-CG 3.25Å; A142-L146 PolarHBondContact O-N 3.24Å; A142-W174 HydrophobicContact CB-CD2 3.92Å; A142-W174 HydrophobicContact CB-CE3 3.85Å; A142-W174 HydrophobicContact CB-CH2 4.14Å; A142-W174 HydrophobicContact CB-CZ2 4.2Å; A142-W174 HydrophobicContact CB-CZ3 3.96Å; A142-A177 HydrophobicContact CB-CB 3.82Å
143	Q	95.4	Very high	91.6	Very high	40 Å²	40	37.6 Å²	37.6	19%	0.187	21%	0.213	C	C	.	.	H	α-helix	trans	-62.5	-45.9	177.5	-71.7	172.1	55.4	0	0	112.5	L102 G105 S139 A140 F141 L146 L147	L102-Q143 HydrophobicContact CD2-CB 3.95Å; L102-Q143 HydrophobicContact CD2-CG 3.93Å; G105-Q143 PolarHBondContact O-NE2 3.2Å; S139-Q143 VanDerWaalsContact O-CG 3.23Å; S139-Q143 WeakPolarHBondContact O-CG 3.24Å; S139-Q143 PolarHBondContact O-N 3.49Å; S139-Q143 VanDerWaalsContact O-N 3.09Å; S139-Q143 PolarHBondContact O-NE2 3.33Å; A140-Q143 PolarHBondContact O-N 3.33Å; F141-Q143 VanDerWaalsContact C-N 3.33Å; F141-Q143 PolarHBondContact O-N 2.96Å; Q143-L146 PolarHBondContact O-N 3.13Å; Q143-L147 WeakPolarHBondContact O-CG 3.34Å; Q143-L147 PolarHBondContact O-N 3.2Å
144	A	95.1	Very high	90.6	Very high	18 Å²	18	37.4 Å²	37.4	15%	0.149	22%	0.22	C	C	.	.	H	α-helix	trans	-63.8	-43.5	178.8	0	0	0	0	0	112.2	A140 F141 L147 G148 I217 F218	A140-A144 PolarHBondContact O-N 3.04Å; F141-A144 PolarHBondContact O-N 3.26Å; A144-L147 PolarHBondContact O-N 2.88Å; A144-G148 PolarHBondContact O-N 3.34Å; A144-I217 HydrophobicContact CB-CG2 3.56Å; A144-F218 HydrophobicContact CB-CD1 3.95Å; A144-F218 HydrophobicContact CB-CE1 3.73Å
145	L	94.3	Very high	89.2	Confident	27 Å²	27	42 Å²	42	14%	0.141	24%	0.237	C	C	.	.	H	α-helix	trans	-64.8	-43.2	175.9	-71.7	172	0	0	0	111.6	F141 A142 L147 G148 C149 I173 V176 L180 I217	F141-L145 WeakPolarHBondContact O-CB 3.46Å; F141-L145 VanDerWaalsContact O-CG 3.26Å; F141-L145 WeakPolarHBondContact O-CG 3.29Å; F141-L145 PolarHBondContact O-N 3.03Å; A142-L145 PolarHBondContact O-N 3.12Å; L145-L147 PolarHBondContact O-N 3.38Å; L145-G148 PolarHBondContact O-N 3.26Å; L145-C149 VanDerWaalsContact O-CB 3.28Å; L145-C149 WeakPolarHBondContact O-CB 3.4Å; L145-C149 PolarHBondContact O-N 2.85Å; L145-C149 PolarHBondContact O-SG 2.93Å; L145-I173 HydrophobicContact CB-CG2 3.68Å; L145-I173 HydrophobicContact CD1-CG2 4.31Å; L145-V176 HydrophobicContact CD1-CB 4.44Å; L145-V176 HydrophobicContact CD1-CG1 3.96Å; L145-L180 HydrophobicContact CD1-CD1 4.25Å; L145-I217 HydrophobicContact CD2-CD1 3.87Å
146	L	92.1	Very high	87.5	Confident	8 Å²	8	49 Å²	49	4%	0.042	26%	0.259	C	S	.	.	H	α-helix	trans	-58.1	-47.3	175.3	-78.7	164.4	0	0	0	111.6	Q101 L102 A142 Q143 H150 I173	Q101-L146 HydrophobicContact CB-CD1 3.6Å; Q101-L146 HydrophobicContact CB-CD2 4.38Å; L102-L146 HydrophobicContact CD2-CB 4.32Å; L102-L146 HydrophobicContact CD2-CD1 4.42Å; A142-L146 VanDerWaalsContact O-CB 3.3Å; A142-L146 WeakPolarHBondContact O-CB 3.47Å; A142-L146 WeakPolarHBondContact O-CD1 3.49Å; A142-L146 WeakPolarHBondContact O-CG 3.25Å; A142-L146 PolarHBondContact O-N 3.24Å; Q143-L146 PolarHBondContact O-N 3.13Å; L146-H150 VanDerWaalsContact O-CB 3.26Å; L146-H150 WeakPolarHBondContact O-CB 3.2Å; L146-H150 PolarHBondContact O-N 3.12Å; L146-I173 HydrophobicContact CD2-CD1 3.68Å; L146-I173 HydrophobicContact CD2-CG2 4.43Å; L146-I173 HydrophobicContact CG-CD1 4.24Å; L146-I173 HydrophobicContact CG-CG2 4.02Å
147	L	91.1	Very high	85.9	Confident	95 Å²	95	47.4 Å²	47.4	50%	0.497	26%	0.256	S	S	.	.	H	α-helix	trans	-64.1	-42.7	177.5	-70.7	171.3	0	0	0	111.6	L102 Q143 A144 L145 H150 A151	L102-L147 HydrophobicContact CD1-CD2 3.89Å; L102-L147 HydrophobicContact CD2-CD2 4.36Å; L102-L147 HydrophobicContact CD2-CG 4.11Å; Q143-L147 WeakPolarHBondContact O-CG 3.34Å; Q143-L147 PolarHBondContact O-N 3.2Å; A144-L147 PolarHBondContact O-N 2.88Å; L145-L147 PolarHBondContact O-N 3.38Å; L147-H150 PolarHBondContact O-N 2.91Å; L147-A151 VanDerWaalsContact O-CB 3.27Å; L147-A151 WeakPolarHBondContact O-CB 3.44Å; L147-A151 PolarHBondContact O-N 3.46Å
148	G	89.8	Confident	84	Confident	6 Å²	6	47.8 Å²	47.8	6%	0.062	28%	0.277	C	S	.	.	H	α-helix	trans	-65.2	-44.4	177.6	0	0	0	0	0	113.3	A144 L145 A151 S152	A144-G148 PolarHBondContact O-N 3.34Å; L145-G148 PolarHBondContact O-N 3.26Å; G148-A151 PolarHBondContact O-N 3.38Å; G148-S152 WeakPolarHBondContact O-CB 3.29Å; G148-S152 PolarHBondContact O-N 3.49Å; G148-S152 PolarHBondContact O-OG 3.43Å
149	C	88	Confident	81.8	Confident	31 Å²	31	52 Å²	52	21%	0.209	31%	0.311	C	S	.	.	H	α-helix	trans	-62.3	-44.6	173.6	-74.2	0	0	0	0	111.3	L145 A151 S152 L153 I173	L145-C149 VanDerWaalsContact O-CB 3.28Å; L145-C149 WeakPolarHBondContact O-CB 3.4Å; L145-C149 PolarHBondContact O-N 2.85Å; L145-C149 PolarHBondContact O-SG 2.93Å; C149-A151 PolarHBondContact O-N 2.84Å; C149-S152 WeakPolarHBondContact CA-OG 3.42Å; C149-S152 PolarHBondContact O-N 3.36Å; C149-S152 PolarHBondContact O-OG 3.29Å; C149-S152 VanDerWaalsContact O-OG 3.11Å; C149-L153 WeakPolarHBondContact O-CB 3.16Å; C149-L153 PolarHBondContact O-N 2.71Å; C149-I173 HydrophobicContact CB-CD1 4.23Å
150	H	84.8	Confident	79.9	Confident	85 Å²	85	54.2 Å²	54.2	39%	0.394	33%	0.334	S	S	.	.	H	α-helix	trans	-65.2	-39.9	177.9	-174.7	-97.7	0	0	0	112	L146 L147 S152 G154	L146-H150 VanDerWaalsContact O-CB 3.26Å; L146-H150 WeakPolarHBondContact O-CB 3.2Å; L146-H150 PolarHBondContact O-N 3.12Å; L147-H150 PolarHBondContact O-N 2.91Å; H150-S152 VanDerWaalsContact C-N 3.32Å; H150-S152 PolarHBondContact O-N 3.47Å; H150-G154 WeakPolarHBondContact O-CA 3.2Å; H150-G154 PolarHBondContact O-N 3.41Å
151	A	84.9	Confident	78.1	Confident	69 Å²	69	57.8 Å²	57.8	57%	0.57	35%	0.348	S	S	*	.	H	α-helix	trans	-65.8	-32.8	177.1	0	0	0	0	0	113.2	L147 G148 C149 L225	L147-A151 VanDerWaalsContact O-CB 3.27Å; L147-A151 WeakPolarHBondContact O-CB 3.44Å; L147-A151 PolarHBondContact O-N 3.46Å; G148-A151 PolarHBondContact O-N 3.38Å; C149-A151 PolarHBondContact O-N 2.84Å; A151-L225 HydrophobicContact CB-CD1 4.15Å; A151-L225 HydrophobicContact CB-CD2 4.44Å
152	S	82.1	Confident	76.4	Confident	57 Å²	57	62 Å²	62	40%	0.399	37%	0.374	S	S	.	.	H	α-helix	trans	-88.9	-44	-178.6	51.4	0	0	0	0	113.2	G148 C149 H150 H155	G148-S152 WeakPolarHBondContact O-CB 3.29Å; G148-S152 PolarHBondContact O-N 3.49Å; G148-S152 PolarHBondContact O-OG 3.43Å; C149-S152 WeakPolarHBondContact CA-OG 3.42Å; C149-S152 PolarHBondContact O-N 3.36Å; C149-S152 PolarHBondContact O-OG 3.29Å; C149-S152 VanDerWaalsContact O-OG 3.11Å; H150-S152 VanDerWaalsContact C-N 3.32Å; H150-S152 PolarHBondContact O-N 3.47Å; S152-H155 PolarHBondContact O-CE1 3.4Å; S152-H155 PolarHBondContact O-ND1 3.2Å
153	L	76.5	Confident	74.7	Confident	80 Å²	80	67.2 Å²	67.2	42%	0.419	41%	0.408	S	S	.	.	H	α-helix	trans	-102	-1	-174.2	-70.7	122.1	0	0	0	114.4	C149 H155 R156 L157	C149-L153 WeakPolarHBondContact O-CB 3.16Å; C149-L153 PolarHBondContact O-N 2.71Å; L153-H155 PolarHBondContact O-N 3.07Å; L153-H155 VanDerWaalsContact O-N 3.1Å; L153-R156 PolarHBondContact O-N 2.99Å; L153-L157 HydrophobicContact CB-CD1 3.95Å; L153-L157 HydrophobicContact CB-CG 4.44Å; L153-L157 PolarHBondContact O-N 3.28Å
154	G	69.8	Low	73.1	Confident	26 Å²	26	68 Å²	68	27%	0.268	43%	0.426	S	S	.	.	H	α-helix	trans	-53.2	-36.9	-174.5	0	0	0	0	0	114.6	H150 R156 L157 G158	H150-G154 WeakPolarHBondContact O-CA 3.2Å; H150-G154 PolarHBondContact O-N 3.41Å; G154-R156 VanDerWaalsContact C-N 3.32Å; G154-R156 PolarHBondContact O-N 3.02Å; G154-L157 PolarHBondContact O-N 3.46Å; G154-G158 PolarHBondContact O-N 2.93Å
155	H	64.8	Low	71.8	Confident	135 Å²	135	72.8 Å²	72.8	63%	0.625	45%	0.449	S	S	*	.	H	α-helix	trans	-64.3	-31.2	175.4	70.4	-67.9	0	0	0	113.9	S152 L153	S152-H155 PolarHBondContact O-CE1 3.4Å; S152-H155 PolarHBondContact O-ND1 3.2Å; L153-H155 PolarHBondContact O-N 3.07Å; L153-H155 VanDerWaalsContact O-N 3.1Å
156	R	60.8	Low	70.9	Confident	189 Å²	189	72.7 Å²	72.7	71%	0.713	45%	0.449	S	S	*	.	H	α-helix	trans	-87.3	-26.9	178.4	-60.2	-140.4	179.4	-139.9	4.5	113	L153 G154 G158	L153-R156 PolarHBondContact O-N 2.99Å; G154-R156 VanDerWaalsContact C-N 3.32Å; G154-R156 PolarHBondContact O-N 3.02Å; R156-G158 VanDerWaalsContact C-N 3.31Å
157	L	60.3	Low	70.2	Confident	44 Å²	44	77.8 Å²	77.8	23%	0.23	48%	0.476	C	S	.	.	H	α-helix	trans	-75.1	-20.2	177.3	-71.8	159.9	0	0	0	112.6	L153 G154	L153-L157 HydrophobicContact CB-CD1 3.95Å; L153-L157 HydrophobicContact CB-CG 4.44Å; L153-L157 PolarHBondContact O-N 3.28Å; G154-L157 PolarHBondContact O-N 3.46Å
158	G	55	Low	69.9	Low	65 Å²	65	75.5 Å²	75.5	67%	0.67	48%	0.475	S	S	*	.	S	Bend	trans	-84.1	-17.2	179	0	0	0	0	0	116.2	G154 R156 G160	G154-G158 PolarHBondContact O-N 2.93Å; R156-G158 VanDerWaalsContact C-N 3.31Å; G158-G160 PolarHBondContact O-N 3.05Å
159	A	50	Low	69.7	Low	97 Å²	97	78.3 Å²	78.3	80%	0.802	49%	0.488	S	S	*	.	S	Bend	trans	-87.2	0.5	-173.2	0	0	0	0	0	114.7
160	G	54.3	Low	69.6	Low	48 Å²	48	77.7 Å²	77.7	50%	0.495	48%	0.484	S	S	.	.			trans	159.3	85	-175.8	0	0	0	0	0	109.2	G158 V162	G158-G160 PolarHBondContact O-N 3.05Å; G160-V162 VanDerWaalsContact C-N 3.29Å; G160-V162 PolarHBondContact O-N 3.28Å
161	Q	58.7	Low	69.9	Low	93 Å²	93	78.2 Å²	78.2	44%	0.435	49%	0.493	S	S	.	.			trans	-71	85.7	-177.7	-165.2	165.5	4.4	0	0	109.3	P163	Q161-P163 VanDerWaalsContact O-CD 3.24Å; Q161-P163 WeakPolarHBondContact O-CD 3.14Å
162	V	59.6	Low	70.3	Confident	90 Å²	90	76.7 Å²	76.7	55%	0.545	48%	0.484	S	S	.	.			trans	-70.5	114.8	175.6	-175.4	0	0	0	0	107.9	G160 G164 L165 T166	G160-V162 VanDerWaalsContact C-N 3.29Å; G160-V162 PolarHBondContact O-N 3.28Å; V162-G164 PolarHBondContact O-N 2.82Å; V162-G164 VanDerWaalsContact O-N 3.11Å; V162-L165 HydrophobicContact CB-CB 4.22Å; V162-L165 PolarHBondContact O-N 3.42Å; V162-T166 PolarHBondContact O-N 3.14Å; V162-T166 PolarHBondContact O-OG1 2.92Å
163	P	60.9	Low	70.9	Confident	109 Å²	109	74.5 Å²	74.5	71%	0.708	47%	0.468	S	S	*	.	H	α-helix	trans	-55.9	-35.5	-171.8	-27.1	35.2	0	0	0	113.8	Q161 L167	Q161-P163 VanDerWaalsContact O-CD 3.24Å; Q161-P163 WeakPolarHBondContact O-CD 3.14Å; P163-L167 PolarHBondContact O-N 3.18Å; P163-L167 VanDerWaalsContact O-N 3.1Å
164	G	62.3	Low	71.8	Confident	56 Å²	56	73.8 Å²	73.8	58%	0.577	46%	0.459	S	S	*	.	H	α-helix	trans	-68.4	-36.1	178	0	0	0	0	0	114.2	V162 G168	V162-G164 PolarHBondContact O-N 2.82Å; V162-G164 VanDerWaalsContact O-N 3.11Å; G164-G168 PolarHBondContact O-N 3.04Å
165	L	68.6	Low	73	Confident	118 Å²	118	74.6 Å²	74.6	62%	0.618	47%	0.468	S	S	*	.	H	α-helix	trans	-70.4	-39.2	178.2	-175.2	66.7	0	0	0	111	V162 L169	V162-L165 HydrophobicContact CB-CB 4.22Å; V162-L165 PolarHBondContact O-N 3.42Å; L165-L169 VanDerWaalsContact O-CB 3.31Å; L165-L169 WeakPolarHBondContact O-CB 3.46Å; L165-L169 PolarHBondContact O-N 2.88Å
166	T	73.8	Confident	74.5	Confident	26 Å²	26	71.7 Å²	71.7	16%	0.16	46%	0.46	C	S	.	.	H	α-helix	trans	-65.9	-44.2	176.4	-51.1	0	0	0	0	111.4	V162 L169 T170	V162-T166 PolarHBondContact O-N 3.14Å; V162-T166 PolarHBondContact O-OG1 2.92Å; T166-L169 PolarHBondContact O-N 3.43Å; T166-T170 WeakPolarHBondContact O-CG2 3.49Å; T166-T170 PolarHBondContact O-N 3.12Å; T166-T170 PolarHBondContact O-OG1 3.27Å
167	L	78.4	Confident	76.2	Confident	115 Å²	115	62.7 Å²	62.7	60%	0.602	43%	0.426	S	S	*	.	H	α-helix	trans	-64	-48.8	178.2	-171.9	66.8	0	0	0	111.4	P163 L169 T170 V171	P163-L167 PolarHBondContact O-N 3.18Å; P163-L167 VanDerWaalsContact O-N 3.1Å; L167-L169 VanDerWaalsContact C-N 3.31Å; L167-L169 PolarHBondContact O-N 3.49Å; L167-T170 PolarHBondContact O-N 3.22Å; L167-T170 VanDerWaalsContact O-N 3.17Å; L167-T170 PolarHBondContact O-OG1 2.9Å; L167-V171 WeakPolarHBondContact O-CG2 3.32Å; L167-V171 PolarHBondContact O-N 2.84Å
168	G	84.3	Confident	77.8	Confident	47 Å²	47	63.1 Å²	63.1	49%	0.485	44%	0.435	S	S	.	.	H	α-helix	trans	-58.7	-41.3	178.1	0	0	0	0	0	112.9	G164 G172	G164-G168 PolarHBondContact O-N 3.04Å; G168-G172 PolarHBondContact O-N 3.48Å
169	L	85.6	Confident	79.7	Confident	64 Å²	64	65.7 Å²	65.7	34%	0.335	43%	0.433	S	S	.	.	H	α-helix	trans	-62	-46.9	175.2	-175.4	74.8	0	0	0	111.6	L165 T166 L167 G172 I173	L165-L169 VanDerWaalsContact O-CB 3.31Å; L165-L169 WeakPolarHBondContact O-CB 3.46Å; L165-L169 PolarHBondContact O-N 2.88Å; T166-L169 PolarHBondContact O-N 3.43Å; L167-L169 VanDerWaalsContact C-N 3.31Å; L167-L169 PolarHBondContact O-N 3.49Å; L169-G172 PolarHBondContact O-N 2.84Å; L169-I173 HydrophobicContact CD1-CD1 4.34Å; L169-I173 HydrophobicContact CD2-CD1 4.43Å; L169-I173 HydrophobicContact CG-CD1 3.91Å; L169-I173 VanDerWaalsContact O-CG1 3.28Å; L169-I173 WeakPolarHBondContact O-CG1 3.46Å; L169-I173 PolarHBondContact O-N 3.37Å
170	T	86.9	Confident	81.8	Confident	18 Å²	18	63.2 Å²	63.2	11%	0.11	41%	0.406	C	S	.	.	H	α-helix	trans	-62.6	-48.4	179.6	55.4	0	0	0	0	111.9	Q101 T166 L167 G172 I173 W174	Q101-T170 HydrophobicContact CG-CG2 4.05Å; T166-T170 WeakPolarHBondContact O-CG2 3.49Å; T166-T170 PolarHBondContact O-N 3.12Å; T166-T170 PolarHBondContact O-OG1 3.27Å; L167-T170 PolarHBondContact O-N 3.22Å; L167-T170 VanDerWaalsContact O-N 3.17Å; L167-T170 PolarHBondContact O-OG1 2.9Å; T170-G172 VanDerWaalsContact C-N 3.29Å; T170-G172 PolarHBondContact O-N 2.82Å; T170-I173 PolarHBondContact O-N 2.65Å; T170-W174 PolarHBondContact O-N 3.12Å
171	V	90.9	Very high	83.6	Confident	96 Å²	96	61.1 Å²	61.1	58%	0.582	38%	0.384	S	S	*	.	H	α-helix	trans	-59.8	-43	177.3	174.7	0	0	0	0	110.7	L167 W174 G175	L167-V171 WeakPolarHBondContact O-CG2 3.32Å; L167-V171 PolarHBondContact O-N 2.84Å; V171-W174 PolarHBondContact O-N 3.23Å; V171-G175 PolarHBondContact O-N 3.3Å
172	G	93.2	Very high	85.2	Confident	37 Å²	37	60.9 Å²	60.9	38%	0.381	39%	0.385	S	S	.	.	H	α-helix	trans	-60	-45.4	175.7	0	0	0	0	0	112.8	G168 L169 T170 G175 V176	G168-G172 PolarHBondContact O-N 3.48Å; L169-G172 PolarHBondContact O-N 2.84Å; T170-G172 VanDerWaalsContact C-N 3.29Å; T170-G172 PolarHBondContact O-N 2.82Å; G172-G175 PolarHBondContact O-N 3.39Å; G172-V176 WeakPolarHBondContact O-CG2 3.32Å; G172-V176 PolarHBondContact O-N 3.47Å
173	I	94.4	Very high	86.5	Confident	12 Å²	12	57.3 Å²	57.3	6%	0.062	36%	0.364	C	S	.	.	H	α-helix	trans	-62.6	-45.7	178.8	-70.4	166.2	0	0	0	111.2	L145 L146 C149 L169 T170 G175 V176 A177	L145-I173 HydrophobicContact CB-CG2 3.68Å; L145-I173 HydrophobicContact CD1-CG2 4.31Å; L146-I173 HydrophobicContact CD2-CD1 3.68Å; L146-I173 HydrophobicContact CD2-CG2 4.43Å; L146-I173 HydrophobicContact CG-CD1 4.24Å; L146-I173 HydrophobicContact CG-CG2 4.02Å; C149-I173 HydrophobicContact CB-CD1 4.23Å; L169-I173 HydrophobicContact CD1-CD1 4.34Å; L169-I173 HydrophobicContact CD2-CD1 4.43Å; L169-I173 HydrophobicContact CG-CD1 3.91Å; L169-I173 VanDerWaalsContact O-CG1 3.28Å; L169-I173 WeakPolarHBondContact O-CG1 3.46Å; L169-I173 PolarHBondContact O-N 3.37Å; T170-I173 PolarHBondContact O-N 2.65Å; I173-G175 VanDerWaalsContact C-N 3.34Å; I173-G175 PolarHBondContact O-N 3.29Å; I173-V176 PolarHBondContact O-N 3.16Å; I173-A177 WeakPolarHBondContact O-CB 3.44Å; I173-A177 PolarHBondContact O-N 3.24Å
174	W	95.4	Very high	87.8	Confident	64 Å²	64	52.2 Å²	52.2	24%	0.242	33%	0.33	C	S	.	.	H	α-helix	trans	-65	-37.9	176.6	-78.5	99.5	0	0	0	112.4	V104 L108 A142 T170 V171 A177 A178	V104-W174 HydrophobicContact CG1-CH2 4.26Å; V104-W174 HydrophobicContact CG1-CZ2 4.13Å; L108-W174 HydrophobicContact CD1-CH2 3.86Å; L108-W174 HydrophobicContact CD1-CZ3 4.02Å; A142-W174 HydrophobicContact CB-CD2 3.92Å; A142-W174 HydrophobicContact CB-CE3 3.85Å; A142-W174 HydrophobicContact CB-CH2 4.14Å; A142-W174 HydrophobicContact CB-CZ2 4.2Å; A142-W174 HydrophobicContact CB-CZ3 3.96Å; T170-W174 PolarHBondContact O-N 3.12Å; V171-W174 PolarHBondContact O-N 3.23Å; W174-A177 PolarHBondContact O-N 3.08Å; W174-A178 WeakPolarHBondContact O-CB 3.34Å; W174-A178 PolarHBondContact O-N 2.88Å
175	G	95.7	Very high	89	Confident	44 Å²	44	50.6 Å²	50.6	45%	0.454	31%	0.309	S	S	.	.	H	α-helix	trans	-62.6	-45.9	174.3	0	0	0	0	0	112.6	V171 G172 I173 A178 L179	V171-G175 PolarHBondContact O-N 3.3Å; G172-G175 PolarHBondContact O-N 3.39Å; I173-G175 VanDerWaalsContact C-N 3.34Å; I173-G175 PolarHBondContact O-N 3.29Å; G175-A178 PolarHBondContact O-N 3.32Å; G175-L179 PolarHBondContact O-N 2.92Å
176	V	96	Very high	89.9	Confident	74 Å²	74	50 Å²	50	45%	0.448	31%	0.306	S	S	.	.	H	α-helix	trans	-63.4	-43.3	174.8	172.3	0	0	0	0	110.7	L145 G172 I173 A178 L179 L180	L145-V176 HydrophobicContact CD1-CB 4.44Å; L145-V176 HydrophobicContact CD1-CG1 3.96Å; G172-V176 WeakPolarHBondContact O-CG2 3.32Å; G172-V176 PolarHBondContact O-N 3.47Å; I173-V176 PolarHBondContact O-N 3.16Å; V176-A178 VanDerWaalsContact C-N 3.33Å; V176-A178 PolarHBondContact O-N 3.2Å; V176-L179 PolarHBondContact O-N 2.92Å; V176-L179 VanDerWaalsContact O-N 3.16Å; V176-L180 HydrophobicContact CG1-CD1 4.01Å; V176-L180 HydrophobicContact CG1-CG 4.3Å; V176-L180 VanDerWaalsContact O-CG 3.32Å; V176-L180 WeakPolarHBondContact O-CG 3.32Å; V176-L180 PolarHBondContact O-N 3.1Å
177	A	95.6	Very high	90.4	Very high	0 Å²	0	48.8 Å²	48.8	0%	0	30%	0.299	C	S	.	.	H	α-helix	trans	-59.5	-44.7	176.9	0	0	0	0	0	111.5	G138 F141 A142 I173 W174 L179 L180 T181	G138-A177 WeakPolarHBondContact O-CB 3.41Å; F141-A177 HydrophobicContact CB-CB 3.92Å; A142-A177 HydrophobicContact CB-CB 3.82Å; I173-A177 WeakPolarHBondContact O-CB 3.44Å; I173-A177 PolarHBondContact O-N 3.24Å; W174-A177 PolarHBondContact O-N 3.08Å; A177-L179 PolarHBondContact O-N 3.42Å; A177-L180 PolarHBondContact O-N 2.77Å; A177-T181 WeakPolarHBondContact O-CG2 3.27Å; A177-T181 PolarHBondContact O-N 3.08Å
178	A	93.8	Very high	90.7	Very high	52 Å²	52	43.7 Å²	43.7	43%	0.43	27%	0.273	S	S	.	.	H	α-helix	trans	-60	-44.3	174.2	0	0	0	0	0	111.6	W174 G175 V176 L180 T181	W174-A178 WeakPolarHBondContact O-CB 3.34Å; W174-A178 PolarHBondContact O-N 2.88Å; G175-A178 PolarHBondContact O-N 3.32Å; V176-A178 VanDerWaalsContact C-N 3.33Å; V176-A178 PolarHBondContact O-N 3.2Å; A178-L180 VanDerWaalsContact C-N 3.33Å; A178-L180 PolarHBondContact O-N 2.63Å; A178-T181 PolarHBondContact O-N 2.75Å; A178-T181 VanDerWaalsContact O-N 3.08Å; A178-T181 PolarHBondContact O-OG1 2.91Å
179	L	94.6	Very high	90.6	Very high	120 Å²	120	41.5 Å²	41.5	63%	0.628	25%	0.251	S	S	*	.	H	α-helix	trans	-61.4	-40	177.4	-173.1	62.8	0	0	0	112.7	G175 V176 A177 T181 L182	G175-L179 PolarHBondContact O-N 2.92Å; V176-L179 PolarHBondContact O-N 2.92Å; V176-L179 VanDerWaalsContact O-N 3.16Å; A177-L179 PolarHBondContact O-N 3.42Å; L179-T181 PolarHBondContact O-N 3.31Å; L179-L182 VanDerWaalsContact O-CB 3.3Å; L179-L182 WeakPolarHBondContact O-CB 3.3Å; L179-L182 PolarHBondContact O-N 2.04Å; L179-L182 VanDerWaalsContact O-N 3.12Å
180	L	93.8	Very high	90.4	Very high	45 Å²	45	40.1 Å²	40.1	24%	0.236	25%	0.249	C	C	.	.	H	α-helix	trans	-65.5	-18.2	176.9	-69.7	172.3	0	0	0	113.3	F141 L145 V176 A177 A178 P183 A213 I217	F141-L180 HydrophobicContact CB-CD1 4.45Å; F141-L180 HydrophobicContact CD1-CD1 4.26Å; F141-L180 HydrophobicContact CD2-CB 3.82Å; F141-L180 HydrophobicContact CE2-CB 3.91Å; F141-L180 HydrophobicContact CG-CB 4.26Å; F141-L180 HydrophobicContact CG-CD1 4.23Å; F141-L180 HydrophobicContact CZ-CB 4.41Å; L145-L180 HydrophobicContact CD1-CD1 4.25Å; V176-L180 HydrophobicContact CG1-CD1 4.01Å; V176-L180 HydrophobicContact CG1-CG 4.3Å; V176-L180 VanDerWaalsContact O-CG 3.32Å; V176-L180 WeakPolarHBondContact O-CG 3.32Å; V176-L180 PolarHBondContact O-N 3.1Å; A177-L180 PolarHBondContact O-N 2.77Å; A178-L180 VanDerWaalsContact C-N 3.33Å; A178-L180 PolarHBondContact O-N 2.63Å; L180-P183 WeakPolarHBondContact O-CD 3.41Å; L180-A213 HydrophobicContact CD2-CB 4.17Å; L180-I217 HydrophobicContact CD1-CG1 4.34Å
181	T	93.4	Very high	89.9	Confident	4 Å²	4	41.3 Å²	41.3	3%	0.025	26%	0.258	C	S	.	.	H	α-helix	trans	-85.2	-16.5	174.6	67.5	0	0	0	0	113.8	F141 A177 A178 L179 P183 V184 T185	F141-T181 HydrophobicContact CD2-CG2 4.13Å; F141-T181 HydrophobicContact CE2-CG2 4.45Å; A177-T181 WeakPolarHBondContact O-CG2 3.27Å; A177-T181 PolarHBondContact O-N 3.08Å; A178-T181 PolarHBondContact O-N 2.75Å; A178-T181 VanDerWaalsContact O-N 3.08Å; A178-T181 PolarHBondContact O-OG1 2.91Å; L179-T181 PolarHBondContact O-N 3.31Å; T181-P183 VanDerWaalsContact C-N 3.26Å; T181-P183 VanDerWaalsContact O-N 3.12Å; T181-V184 WeakPolarHBondContact O-CG1 3.03Å; T181-V184 PolarHBondContact O-N 3.23Å; T181-T185 WeakPolarHBondContact O-CG2 3.42Å; T181-T185 PolarHBondContact O-N 3.11Å; T181-T185 PolarHBondContact O-OG1 3.47Å
182	L	91.8	Very high	88.9	Confident	88 Å²	88	40.5 Å²	40.5	46%	0.461	27%	0.269	S	S	.	.	H	α-helix	trans	-49.3	-44.8	-177.5	-172.1	69	0	0	0	112.5	L179 V184 T185 L186	L179-L182 VanDerWaalsContact O-CB 3.3Å; L179-L182 WeakPolarHBondContact O-CB 3.3Å; L179-L182 PolarHBondContact O-N 2.04Å; L179-L182 VanDerWaalsContact O-N 3.12Å; L182-V184 PolarHBondContact O-N 3.47Å; L182-T185 WeakPolarHBondContact CA-OG1 3.35Å; L182-T185 PolarHBondContact O-N 3.42Å; L182-T185 PolarHBondContact O-OG1 3.06Å; L182-L186 HydrophobicContact CD1-CD1 3.99Å; L182-L186 HydrophobicContact CD1-CG 4.19Å; L182-L186 HydrophobicContact CG-CD1 3.85Å; L182-L186 HydrophobicContact CG-CG 4.41Å; L182-L186 WeakPolarHBondContact O-CG 3.38Å; L182-L186 PolarHBondContact O-N 3.5Å; L182-L186 VanDerWaalsContact O-N 3.15Å
183	P	87.7	Confident	87.8	Confident	14 Å²	14	39.8 Å²	39.8	9%	0.091	26%	0.261	C	S	.	.	H	α-helix	trans	-61.7	-42.9	179.6	-24.7	36.8	0	0	0	114.4	L180 T181 A187 L206 T209 H210	L180-P183 WeakPolarHBondContact O-CD 3.41Å; T181-P183 VanDerWaalsContact C-N 3.26Å; T181-P183 VanDerWaalsContact O-N 3.12Å; P183-A187 VanDerWaalsContact O-CB 3.27Å; P183-A187 WeakPolarHBondContact O-CB 3.16Å; P183-A187 PolarHBondContact O-N 2.87Å; P183-A187 VanDerWaalsContact O-N 3.16Å; P183-L206 VanDerWaalsContact CA-CG 3.45Å; P183-L206 HydrophobicContact CB-CD1 3.81Å; P183-L206 HydrophobicContact CB-CG 3.67Å; P183-L206 WeakPolarHBondContact CB-O 3.28Å; P183-L206 HydrophobicContact CG-CD1 4.31Å; P183-L206 VanDerWaalsContact O-CD2 3.27Å; P183-L206 WeakPolarHBondContact O-CD2 3.44Å; P183-L206 WeakPolarHBondContact O-CG 3.44Å; P183-T209 HydrophobicContact CG-CG2 3.97Å; P183-H210 HydrophobicContact CB-CB 4.06Å
184	V	87.3	Confident	87	Confident	2 Å²	2	42.2 Å²	42.2	1%	0.012	27%	0.274	C	S	.	.	H	α-helix	trans	-73.4	-35.7	-179.4	60.8	0	0	0	0	111.8	Y133 Y137 T181 L182 A187 S188 L197	Y133-V184 HydrophobicContact CD1-CG2 4.31Å; Y133-V184 HydrophobicContact CG-CG2 4.23Å; Y137-V184 HydrophobicContact CD2-CB 4.42Å; Y137-V184 HydrophobicContact CD2-CG1 3.87Å; Y137-V184 HydrophobicContact CD2-CG2 3.9Å; Y137-V184 HydrophobicContact CE2-CG2 3.78Å; Y137-V184 HydrophobicContact CG-CG1 4.27Å; T181-V184 WeakPolarHBondContact O-CG1 3.03Å; T181-V184 PolarHBondContact O-N 3.23Å; L182-V184 PolarHBondContact O-N 3.47Å; V184-A187 CarbonylContact O-C 3.58Å; V184-A187 PolarHBondContact O-N 2.87Å; V184-S188 VanDerWaalsContact O-CB 3.27Å; V184-S188 WeakPolarHBondContact O-CB 3.42Å; V184-S188 PolarHBondContact O-N 2.96Å; V184-S188 VanDerWaalsContact O-N 3.13Å; V184-S188 PolarHBondContact O-OG 2.84Å; V184-L197 HydrophobicContact CG2-CD1 3.8Å
185	T	88.6	Confident	86.5	Confident	22 Å²	22	39.9 Å²	39.9	14%	0.135	27%	0.267	C	S	.	.	H	α-helix	trans	-64.3	-44.1	179.1	59.4	0	0	0	0	111.9	S130 C134 T181 L182 A187 S188	S130-T185 PolarHBondContact OG-O 2.79Å; C134-T185 HydrophobicContact CB-CG2 3.42Å; C134-T185 VanDerWaalsContact CB-CG2 3.42Å; T181-T185 WeakPolarHBondContact O-CG2 3.42Å; T181-T185 PolarHBondContact O-N 3.11Å; T181-T185 PolarHBondContact O-OG1 3.47Å; L182-T185 WeakPolarHBondContact CA-OG1 3.35Å; L182-T185 PolarHBondContact O-N 3.42Å; L182-T185 PolarHBondContact O-OG1 3.06Å; T185-A187 VanDerWaalsContact C-N 3.34Å; T185-S188 PolarHBondContact O-N 2.88Å; T185-S188 PolarHBondContact O-OG 2.99Å
186	L	86	Confident	85.8	Confident	105 Å²	105	40 Å²	40	55%	0.55	26%	0.259	S	S	.	.	H	α-helix	trans	-71.9	-27.8	178.2	-68	176	0	0	0	112.8	L182 S188 L206	L182-L186 HydrophobicContact CD1-CD1 3.99Å; L182-L186 HydrophobicContact CD1-CG 4.19Å; L182-L186 HydrophobicContact CG-CD1 3.85Å; L182-L186 HydrophobicContact CG-CG 4.41Å; L182-L186 WeakPolarHBondContact O-CG 3.38Å; L182-L186 PolarHBondContact O-N 3.5Å; L182-L186 VanDerWaalsContact O-N 3.15Å; L186-S188 VanDerWaalsContact C-N 3.35Å; L186-L206 HydrophobicContact CB-CD2 3.49Å; L186-L206 VanDerWaalsContact CB-CD2 3.49Å; L186-L206 HydrophobicContact CD1-CD2 4.16Å; L186-L206 HydrophobicContact CG-CD2 4.47Å
187	A	85.3	Confident	84.9	Confident	1 Å²	1	39.8 Å²	39.8	1%	0.008	26%	0.255	C	S	.	.	T	Hydrogen-bonded Turn	trans	-90.2	6.7	177	0	0	0	0	0	113.8	P183 V184 T185 L197 I198 L203 L206	P183-A187 VanDerWaalsContact O-CB 3.27Å; P183-A187 WeakPolarHBondContact O-CB 3.16Å; P183-A187 PolarHBondContact O-N 2.87Å; P183-A187 VanDerWaalsContact O-N 3.16Å; V184-A187 CarbonylContact O-C 3.58Å; V184-A187 PolarHBondContact O-N 2.87Å; T185-A187 VanDerWaalsContact C-N 3.34Å; A187-L197 HydrophobicContact CB-CD1 4Å; A187-L197 HydrophobicContact CB-CG 4.21Å; A187-L197 CarbonylContact O-C 3.55Å; A187-L197 WeakPolarHBondContact O-CA 3.14Å; A187-L197 WeakPolarHBondContact O-CD1 3.38Å; A187-L197 WeakPolarHBondContact O-CG 3.06Å; A187-I198 PolarHBondContact O-N 3.36Å; A187-L203 HydrophobicContact CB-CD2 3.94Å; A187-L206 HydrophobicContact CB-CD2 4.26Å
188	S	84.3	Confident	84	Confident	8 Å²	8	43.4 Å²	43.4	6%	0.056	27%	0.273	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-104.5	148.8	-176.5	65.1	0	0	0	0	112.5	S130 Y133 V184 T185 L186	S130-S188 WeakPolarHBondContact CA-OG 3.47Å; S130-S188 WeakPolarHBondContact CB-OG 3.35Å; S130-S188 PolarHBondContact OG-OG 2.8Å; Y133-S188 VanDerWaalsContact CD2-CB 3.44Å; V184-S188 VanDerWaalsContact O-CB 3.27Å; V184-S188 WeakPolarHBondContact O-CB 3.42Å; V184-S188 PolarHBondContact O-N 2.96Å; V184-S188 VanDerWaalsContact O-N 3.13Å; V184-S188 PolarHBondContact O-OG 2.84Å; T185-S188 PolarHBondContact O-N 2.88Å; T185-S188 PolarHBondContact O-OG 2.99Å; L186-S188 VanDerWaalsContact C-N 3.35Å
189	G	83	Confident	82.6	Confident	2 Å²	2	46.9 Å²	46.9	2%	0.021	28%	0.276	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-154.2	-175.5	176.8	0	0	0	0	0	112.5	T196	G189-T196 PolarHBondContact N-O 2.91Å; G189-T196 PolarHBondContact O-N 3.41Å
190	A	81.8	Confident	81.5	Confident	35 Å²	35	43 Å²	43	29%	0.289	26%	0.26	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-113	127.9	171	0	0	0	0	0	109.6	R124 L194	R124-A190 HydrophobicContact CB-CB 4.39Å; R124-A190 WeakPolarHBondContact O-CB 3.3Å; A190-L194 VanDerWaalsContact CA-O 3.28Å; A190-L194 WeakPolarHBondContact CA-O 3.47Å
191	S	76.6	Confident	80.3	Confident	43 Å²	43	46.7 Å²	46.7	30%	0.301	28%	0.284	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-137.8	135.4	171.7	-178.1	0	0	0	0	109.2	G193 L194	S191-G193 PolarHBondContact O-N 2.95Å; S191-G193 VanDerWaalsContact O-N 3.11Å; S191-L194 PolarHBondContact N-O 3.13Å; S191-L194 PolarHBondContact O-N 3.38Å
192	G	69.7	Low	79.2	Confident	79 Å²	79	54.5 Å²	54.5	81%	0.814	32%	0.32	S	S	*	.	T	Hydrogen-bonded Turn	trans	58.4	25.7	-179.6	0	0	0	0	0	115.1	L194	G192-L194 VanDerWaalsContact C-N 3.28Å; G192-L194 PolarHBondContact O-N 2.73Å
193	G	69.9	Low	78.6	Confident	21 Å²	21	51.9 Å²	51.9	22%	0.216	31%	0.307	C	S	.	.	T	Hydrogen-bonded Turn	trans	81	-0.1	-175.4	0	0	0	0	0	114.9	R124 S191	R124-G193 PolarHBondContact NH1-O 3.09Å; S191-G193 PolarHBondContact O-N 2.95Å; S191-G193 VanDerWaalsContact O-N 3.11Å
194	L	77.6	Confident	78.2	Confident	64 Å²	64	57.3 Å²	57.3	34%	0.335	33%	0.329	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-105.5	150.3	179.6	-66.8	155.5	0	0	0	111	P118 A190 S191 G192 T196	P118-L194 HydrophobicContact CB-CD2 3.72Å; A190-L194 VanDerWaalsContact CA-O 3.28Å; A190-L194 WeakPolarHBondContact CA-O 3.47Å; S191-L194 PolarHBondContact N-O 3.13Å; S191-L194 PolarHBondContact O-N 3.38Å; G192-L194 VanDerWaalsContact C-N 3.28Å; G192-L194 PolarHBondContact O-N 2.73Å; L194-T196 HydrophobicContact CB-CG2 4.25Å
195	C	83.6	Confident	78	Confident	14 Å²	14	60.6 Å²	60.6	10%	0.095	36%	0.356	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-79.7	125.2	166.6	-64.6	0	0	0	0	109	L116 R124 C129 Y133	L116-C195 HydrophobicContact CD2-CB 4.01Å; R124-C195 WeakPolarHBondContact CD-SG 3.36Å; C129-C195 WeakPolarHBondContact CA-SG 3.34Å; C129-C195 HydrophobicContact CB-CB 3.66Å; C129-C195 WeakPolarHBondContact CB-SG 3.42Å; C129-C195 WeakPolarHBondContact SG-CA 3.18Å; C129-C195 WeakPolarHBondContact SG-CB 3.48Å; C129-C195 CovalentContact SG-SG 2.04Å; C129-C195 PolarHBondContact SG-SG 3.33Å; Y133-C195 HydrophobicContact CE2-CB 3.89Å; Y133-C195 PolarHBondContact OH-O 2.88Å
196	T	81.1	Confident	77.8	Confident	47 Å²	47	61.6 Å²	61.6	29%	0.288	36%	0.36	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-135.9	160.3	-177.7	101.1	0	0	0	0	110.4	G189 L194	G189-T196 PolarHBondContact N-O 2.91Å; G189-T196 PolarHBondContact O-N 3.41Å; L194-T196 HydrophobicContact CB-CG2 4.25Å
197	L	77.6	Confident	77.6	Confident	69 Å²	69	57.9 Å²	57.9	36%	0.361	34%	0.34	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-87.1	123.9	168	-149.5	73.3	0	0	0	108.7	V184 A187 Y199 Q207	V184-L197 HydrophobicContact CG2-CD1 3.8Å; A187-L197 HydrophobicContact CB-CD1 4Å; A187-L197 HydrophobicContact CB-CG 4.21Å; A187-L197 CarbonylContact O-C 3.55Å; A187-L197 WeakPolarHBondContact O-CA 3.14Å; A187-L197 WeakPolarHBondContact O-CD1 3.38Å; A187-L197 WeakPolarHBondContact O-CG 3.06Å; L197-Y199 PolarHBondContact O-N 2.87Å; L197-Q207 HydrophobicContact CD2-CG 3.91Å
198	I	76.4	Confident	77.7	Confident	76 Å²	76	60.2 Å²	60.2	39%	0.39	36%	0.36	S	S	.	.			trans	-72.7	123.2	179.3	-56.8	173	0	0	0	108.2	A187 L203 Q207	A187-I198 PolarHBondContact O-N 3.36Å; I198-L203 HydrophobicContact CB-CD1 4.02Å; I198-L203 HydrophobicContact CG2-CD1 3.84Å; I198-Q207 PolarHBondContact O-NE2 3.23Å
199	Y	65.3	Low	77.9	Confident	125 Å²	125	63.6 Å²	63.6	49%	0.49	38%	0.38	S	S	.	.			trans	-100.3	103.3	178	-165.4	-91.6	0	0	0	110	H6 L197	H6-Y199 HydrophobicContact CB-CD1 4.27Å; H6-Y199 HydrophobicContact CB-CE1 4.3Å; H6-Y199 AromaticContact CD2-CE1 3.97Å; H6-Y199 AromaticContact CD2-CZ 3.97Å; L197-Y199 PolarHBondContact O-N 2.87Å
200	S	70.9	Confident	78.2	Confident	40 Å²	40	64.1 Å²	64.1	28%	0.28	38%	0.382	S	S	.	.			trans	-132.8	157.4	170	77.5	0	0	0	0	110.5	E202 L203 K204	S200-E202 PolarHBondContact O-N 3.47Å; S200-L203 PolarHBondContact O-N 2.92Å; S200-L203 VanDerWaalsContact O-N 3.1Å; S200-L203 WeakPolarHBondContact OG-CB 3.37Å; S200-L203 WeakPolarHBondContact OG-CD1 3.08Å; S200-L203 WeakPolarHBondContact OG-CG 3.27Å; S200-L203 PolarHBondContact OG-N 3.31Å; S200-K204 PolarHBondContact O-N 3.38Å; S200-K204 VanDerWaalsContact O-N 3.15Å
201	T	68.4	Low	78.6	Confident	122 Å²	122	66.7 Å²	66.7	75%	0.748	39%	0.394	S	S	*	.	T	Hydrogen-bonded Turn	trans	-55	-38.3	174.6	35.4	0	0	0	0	112	K204	T201-K204 WeakPolarHBondContact O-CB 3.48Å; T201-K204 PolarHBondContact O-N 3.16Å
202	E	71.4	Confident	79.4	Confident	167 Å²	167	69.3 Å²	69.3	78%	0.78	41%	0.408	S	S	*	.	T	Hydrogen-bonded Turn	trans	-67.9	-33.6	177.8	-58.2	-55	130.8	0	0	112.8	S200	S200-E202 PolarHBondContact O-N 3.47Å
203	L	77.6	Confident	80.5	Confident	34 Å²	34	66.2 Å²	66.2	18%	0.178	38%	0.375	C	S	.	.	T	Hydrogen-bonded Turn	trans	-88.2	-6.1	-178.4	-76.1	159.9	0	0	0	113.4	A187 I198 S200 A205 L206 Q207	A187-L203 HydrophobicContact CB-CD2 3.94Å; I198-L203 HydrophobicContact CB-CD1 4.02Å; I198-L203 HydrophobicContact CG2-CD1 3.84Å; S200-L203 PolarHBondContact O-N 2.92Å; S200-L203 VanDerWaalsContact O-N 3.1Å; S200-L203 WeakPolarHBondContact OG-CB 3.37Å; S200-L203 WeakPolarHBondContact OG-CD1 3.08Å; S200-L203 WeakPolarHBondContact OG-CG 3.27Å; S200-L203 PolarHBondContact OG-N 3.31Å; L203-A205 VanDerWaalsContact C-N 3.31Å; L203-A205 PolarHBondContact O-N 2.85Å; L203-L206 HydrophobicContact CD2-CB 4.48Å; L203-L206 HydrophobicContact CD2-CD2 3.79Å; L203-L206 VanDerWaalsContact O-CB 3.31Å; L203-L206 WeakPolarHBondContact O-CB 3.29Å; L203-L206 PolarHBondContact O-N 3.38Å; L203-Q207 WeakPolarHBondContact O-CG 3.27Å; L203-Q207 PolarHBondContact O-N 3.41Å
204	K	79.9	Confident	81.6	Confident	128 Å²	128	66.5 Å²	66.5	56%	0.557	37%	0.373	S	S	*	.	H	α-helix	trans	-59.5	-39.5	-177.4	-170.2	175.1	-177.2	173	0	112.9	S200 T201 L206 Q207 A208	S200-K204 PolarHBondContact O-N 3.38Å; S200-K204 VanDerWaalsContact O-N 3.15Å; T201-K204 WeakPolarHBondContact O-CB 3.48Å; T201-K204 PolarHBondContact O-N 3.16Å; K204-L206 VanDerWaalsContact C-N 3.29Å; K204-L206 PolarHBondContact O-N 2.98Å; K204-Q207 PolarHBondContact O-N 3.03Å; K204-A208 WeakPolarHBondContact O-CB 3.38Å; K204-A208 PolarHBondContact O-N 3.45Å
205	A	82.8	Confident	82.5	Confident	70 Å²	70	67.6 Å²	67.6	58%	0.579	38%	0.379	S	S	*	.	H	α-helix	trans	-62.2	-41	175.9	0	0	0	0	0	111.2	L203 A208 T209	L203-A205 VanDerWaalsContact C-N 3.31Å; L203-A205 PolarHBondContact O-N 2.85Å; A205-A208 PolarHBondContact O-N 3.34Å; A205-T209 PolarHBondContact O-N 3.11Å; A205-T209 PolarHBondContact O-OG1 3.15Å; A205-T209 VanDerWaalsContact O-OG1 3.04Å
206	L	84.6	Confident	83	Confident	43 Å²	43	68.7 Å²	68.7	23%	0.225	39%	0.389	C	S	.	.	H	α-helix	trans	-68.3	-41.8	-177.8	-149.5	63.3	0	0	0	111.8	P183 L186 A187 L203 K204 T209 H210	P183-L206 VanDerWaalsContact CA-CG 3.45Å; P183-L206 HydrophobicContact CB-CD1 3.81Å; P183-L206 HydrophobicContact CB-CG 3.67Å; P183-L206 WeakPolarHBondContact CB-O 3.28Å; P183-L206 HydrophobicContact CG-CD1 4.31Å; P183-L206 VanDerWaalsContact O-CD2 3.27Å; P183-L206 WeakPolarHBondContact O-CD2 3.44Å; P183-L206 WeakPolarHBondContact O-CG 3.44Å; L186-L206 HydrophobicContact CB-CD2 3.49Å; L186-L206 VanDerWaalsContact CB-CD2 3.49Å; L186-L206 HydrophobicContact CD1-CD2 4.16Å; L186-L206 HydrophobicContact CG-CD2 4.47Å; A187-L206 HydrophobicContact CB-CD2 4.26Å; L203-L206 HydrophobicContact CD2-CB 4.48Å; L203-L206 HydrophobicContact CD2-CD2 3.79Å; L203-L206 VanDerWaalsContact O-CB 3.31Å; L203-L206 WeakPolarHBondContact O-CB 3.29Å; L203-L206 PolarHBondContact O-N 3.38Å; K204-L206 VanDerWaalsContact C-N 3.29Å; K204-L206 PolarHBondContact O-N 2.98Å; L206-T209 PolarHBondContact O-N 3Å; L206-H210 PolarHBondContact O-N 2.95Å
207	Q	82.3	Confident	83.7	Confident	27 Å²	27	67.6 Å²	67.6	13%	0.126	38%	0.381	C	S	.	.	H	α-helix	trans	-63.4	-42.1	172.1	-66.1	178.1	-11.5	0	0	112.2	L197 I198 L203 K204 H210 T211	L197-Q207 HydrophobicContact CD2-CG 3.91Å; I198-Q207 PolarHBondContact O-NE2 3.23Å; L203-Q207 WeakPolarHBondContact O-CG 3.27Å; L203-Q207 PolarHBondContact O-N 3.41Å; K204-Q207 PolarHBondContact O-N 3.03Å; Q207-H210 PolarHBondContact O-N 2.83Å; Q207-T211 WeakPolarHBondContact O-CB 3.33Å; Q207-T211 PolarHBondContact O-N 2.89Å; Q207-T211 PolarHBondContact O-OG1 3.25Å
208	A	86.1	Confident	84.5	Confident	51 Å²	51	68.1 Å²	68.1	42%	0.421	38%	0.38	S	S	.	.	H	α-helix	trans	-62	-45.9	175.7	0	0	0	0	0	110.8	K204 A205 H210 T211 V212	K204-A208 WeakPolarHBondContact O-CB 3.38Å; K204-A208 PolarHBondContact O-N 3.45Å; A205-A208 PolarHBondContact O-N 3.34Å; A208-H210 PolarHBondContact O-N 2.95Å; A208-T211 PolarHBondContact O-N 3.46Å; A208-V212 WeakPolarHBondContact O-CB 3.35Å; A208-V212 VanDerWaalsContact O-CG2 3.29Å; A208-V212 WeakPolarHBondContact O-CG2 3.41Å; A208-V212 PolarHBondContact O-N 3.48Å
209	T	88.1	Confident	85.3	Confident	79 Å²	79	68.4 Å²	68.4	49%	0.485	39%	0.385	S	S	.	.	H	α-helix	trans	-58.6	-46.4	175.3	-58.8	0	0	0	0	111.7	P183 A205 L206 T211 V212 A213	P183-T209 HydrophobicContact CG-CG2 3.97Å; A205-T209 PolarHBondContact O-N 3.11Å; A205-T209 PolarHBondContact O-OG1 3.15Å; A205-T209 VanDerWaalsContact O-OG1 3.04Å; L206-T209 PolarHBondContact O-N 3Å; T209-T211 VanDerWaalsContact C-N 3.34Å; T209-T211 PolarHBondContact O-N 3.23Å; T209-V212 PolarHBondContact O-N 3.35Å; T209-A213 WeakPolarHBondContact O-CB 3.28Å; T209-A213 PolarHBondContact O-N 3.37Å
210	H	90.1	Very high	86.6	Confident	13 Å²	13	67 Å²	67	6%	0.06	39%	0.386	C	S	.	.	H	α-helix	trans	-60	-45	176.4	-175.3	59	0	0	0	112	Y137 P183 L206 Q207 A208 V212 A213 C214	Y137-H210 AromaticContact CD1-CE1 3.6Å; Y137-H210 AromaticContact CD1-NE2 3.8Å; Y137-H210 AromaticContact CE1-CE1 3.69Å; Y137-H210 AromaticContact CE1-NE2 3.38Å; Y137-H210 WeakPolarHBondContact CE1-NE2 3.46Å; Y137-H210 AromaticContact CE2-NE2 3.87Å; Y137-H210 AromaticContact CG-CE1 3.84Å; Y137-H210 AromaticContact CZ-NE2 3.42Å; P183-H210 HydrophobicContact CB-CB 4.06Å; L206-H210 PolarHBondContact O-N 2.95Å; Q207-H210 PolarHBondContact O-N 2.83Å; A208-H210 PolarHBondContact O-N 2.95Å; H210-V212 PolarHBondContact O-N 2.77Å; H210-A213 WeakPolarHBondContact O-CB 3.27Å; H210-A213 PolarHBondContact O-N 2.76Å; H210-C214 VanDerWaalsContact CE1-SG 3.52Å; H210-C214 WeakPolarHBondContact O-CB 3.3Å; H210-C214 PolarHBondContact O-N 2.88Å; H210-C214 PolarHBondContact O-SG 2.88Å; H210-C214 VanDerWaalsContact O-SG 3.41Å
211	T	90.5	Very high	87.6	Confident	88 Å²	88	67.7 Å²	67.7	54%	0.54	39%	0.386	S	S	.	.	H	α-helix	trans	-62.3	-44.7	179.5	-56.3	0	0	0	0	111.4	Q207 A208 T209 C214 L215	Q207-T211 WeakPolarHBondContact O-CB 3.33Å; Q207-T211 PolarHBondContact O-N 2.89Å; Q207-T211 PolarHBondContact O-OG1 3.25Å; A208-T211 PolarHBondContact O-N 3.46Å; T209-T211 VanDerWaalsContact C-N 3.34Å; T209-T211 PolarHBondContact O-N 3.23Å; T211-C214 PolarHBondContact O-N 2.93Å; T211-L215 WeakPolarHBondContact O-CB 3.45Å; T211-L215 PolarHBondContact O-N 3.5Å
212	V	93.5	Very high	88.6	Confident	98 Å²	98	64.1 Å²	64.1	59%	0.594	37%	0.365	S	S	*	.	H	α-helix	trans	-62.8	-43.1	176	170.9	0	0	0	0	110.8	A208 T209 H210 L215 A216	A208-V212 WeakPolarHBondContact O-CB 3.35Å; A208-V212 VanDerWaalsContact O-CG2 3.29Å; A208-V212 WeakPolarHBondContact O-CG2 3.41Å; A208-V212 PolarHBondContact O-N 3.48Å; T209-V212 PolarHBondContact O-N 3.35Å; H210-V212 PolarHBondContact O-N 2.77Å; V212-L215 PolarHBondContact O-N 3.01Å; V212-A216 VanDerWaalsContact O-CB 3.29Å; V212-A216 WeakPolarHBondContact O-CB 3.46Å; V212-A216 PolarHBondContact O-N 3.46Å
213	A	92.3	Very high	89.4	Confident	15 Å²	15	61.7 Å²	61.7	12%	0.124	36%	0.357	C	S	.	.	H	α-helix	trans	-61.1	-47.2	175.7	0	0	0	0	0	111.8	F141 L180 T209 H210 L215 A216 I217	F141-A213 HydrophobicContact CZ-CB 4.35Å; L180-A213 HydrophobicContact CD2-CB 4.17Å; T209-A213 WeakPolarHBondContact O-CB 3.28Å; T209-A213 PolarHBondContact O-N 3.37Å; H210-A213 WeakPolarHBondContact O-CB 3.27Å; H210-A213 PolarHBondContact O-N 2.76Å; A213-L215 PolarHBondContact O-N 2.89Å; A213-A216 PolarHBondContact O-N 2.91Å; A213-I217 WeakPolarHBondContact O-CB 3.39Å; A213-I217 VanDerWaalsContact O-CG1 3.32Å; A213-I217 WeakPolarHBondContact O-CG1 3.38Å; A213-I217 PolarHBondContact O-N 3.39Å
214	C	94.3	Very high	89.9	Confident	26 Å²	26	62.1 Å²	62.1	18%	0.176	37%	0.37	C	S	.	.	H	α-helix	trans	-58.8	-46.3	175.5	-75.4	0	0	0	0	112	H210 T211 I217 F218	H210-C214 VanDerWaalsContact CE1-SG 3.52Å; H210-C214 WeakPolarHBondContact O-CB 3.3Å; H210-C214 PolarHBondContact O-N 2.88Å; H210-C214 PolarHBondContact O-SG 2.88Å; H210-C214 VanDerWaalsContact O-SG 3.41Å; T211-C214 PolarHBondContact O-N 2.93Å; C214-I217 PolarHBondContact O-N 3.45Å; C214-F218 HydrophobicContact CB-CD2 4.14Å; C214-F218 HydrophobicContact CB-CE2 4.49Å; C214-F218 WeakPolarHBondContact O-CB 3.5Å; C214-F218 WeakPolarHBondContact O-CD2 3.37Å; C214-F218 PolarHBondContact O-N 3.38Å
215	L	94.9	Very high	90.2	Very high	88 Å²	88	58.6 Å²	58.6	46%	0.461	36%	0.357	S	S	.	.	I	π-helix	trans	-62.8	-44.3	177.6	-179.5	137.4	0	0	0	111.6	T211 V212 A213 V219 L220	T211-L215 WeakPolarHBondContact O-CB 3.45Å; T211-L215 PolarHBondContact O-N 3.5Å; V212-L215 PolarHBondContact O-N 3.01Å; A213-L215 PolarHBondContact O-N 2.89Å; L215-V219 WeakPolarHBondContact O-CA 3.39Å; L215-V219 VanDerWaalsContact O-CB 3.3Å; L215-V219 WeakPolarHBondContact O-CB 3.48Å; L215-V219 PolarHBondContact O-N 3.04Å; L215-V219 VanDerWaalsContact O-N 3.11Å; L215-L220 HydrophobicContact CD2-CD1 3.52Å; L215-L220 HydrophobicContact CD2-CD2 4.34Å; L215-L220 HydrophobicContact CD2-CG 3.73Å; L215-L220 PolarHBondContact O-N 3.29Å
216	A	95.4	Very high	90.4	Very high	36 Å²	36	62.7 Å²	62.7	30%	0.298	36%	0.362	S	S	.	.	I	π-helix	trans	-62.2	-48	178.5	0	0	0	0	0	111.8	V212 A213 L221	V212-A216 VanDerWaalsContact O-CB 3.29Å; V212-A216 WeakPolarHBondContact O-CB 3.46Å; V212-A216 PolarHBondContact O-N 3.46Å; A213-A216 PolarHBondContact O-N 2.91Å; A216-L221 WeakPolarHBondContact O-CB 3.31Å; A216-L221 PolarHBondContact O-N 3.04Å
217	I	94.6	Very high	90.3	Very high	25 Å²	25	62.7 Å²	62.7	13%	0.128	37%	0.372	C	S	.	.	I	π-helix	trans	-82.7	-40	-171.8	-59.3	-56.4	0	0	0	113	F141 A144 L145 L180 A213 C214 P222	F141-I217 HydrophobicContact CD1-CB 4.02Å; F141-I217 HydrophobicContact CD1-CG1 4.14Å; F141-I217 HydrophobicContact CD1-CG2 3.89Å; F141-I217 HydrophobicContact CE1-CB 4.12Å; F141-I217 HydrophobicContact CE1-CG1 4.22Å; F141-I217 HydrophobicContact CE1-CG2 4.47Å; A144-I217 HydrophobicContact CB-CG2 3.56Å; L145-I217 HydrophobicContact CD2-CD1 3.87Å; L180-I217 HydrophobicContact CD1-CG1 4.34Å; A213-I217 WeakPolarHBondContact O-CB 3.39Å; A213-I217 VanDerWaalsContact O-CG1 3.32Å; A213-I217 WeakPolarHBondContact O-CG1 3.38Å; A213-I217 PolarHBondContact O-N 3.39Å; C214-I217 PolarHBondContact O-N 3.45Å; I217-P222 VanDerWaalsContact O-CD 3.29Å; I217-P222 WeakPolarHBondContact O-CD 3.47Å
218	F	93.9	Very high	90.3	Very high	79 Å²	79	64 Å²	64	35%	0.346	39%	0.387	S	S	.	.	I	π-helix	trans	-93	-20.6	-175.7	-61.1	-58	0	0	0	113.9	A140 F141 A144 C214 P222	A140-F218 HydrophobicContact CB-CE1 4.13Å; A140-F218 HydrophobicContact CB-CZ 3.69Å; F141-F218 AromaticContact CD1-CE2 3.92Å; F141-F218 HydrophobicContact CD1-CE2 3.92Å; F141-F218 AromaticContact CD1-CZ 3.77Å; F141-F218 HydrophobicContact CD1-CZ 3.77Å; F141-F218 HydrophobicContact CE1-CD2 4.39Å; F141-F218 AromaticContact CE1-CE2 3.63Å; F141-F218 HydrophobicContact CE1-CE2 3.63Å; F141-F218 AromaticContact CE1-CZ 3.99Å; F141-F218 HydrophobicContact CE1-CZ 3.99Å; F141-F218 HydrophobicContact CG-CZ 4.41Å; F141-F218 HydrophobicContact CZ-CE2 4.3Å; A144-F218 HydrophobicContact CB-CD1 3.95Å; A144-F218 HydrophobicContact CB-CE1 3.73Å; C214-F218 HydrophobicContact CB-CD2 4.14Å; C214-F218 HydrophobicContact CB-CE2 4.49Å; C214-F218 WeakPolarHBondContact O-CB 3.5Å; C214-F218 WeakPolarHBondContact O-CD2 3.37Å; C214-F218 PolarHBondContact O-N 3.38Å; F218-P222 WeakPolarHBondContact O-CG 3.29Å
219	V	94.1	Very high	90	Very high	82 Å²	82	69.3 Å²	69.3	50%	0.497	40%	0.401	S	S	.	.	I	π-helix	trans	-114.4	-61.6	-177.8	-173.6	0	0	0	0	111.2	L215 L221 L223	L215-V219 WeakPolarHBondContact O-CA 3.39Å; L215-V219 VanDerWaalsContact O-CB 3.3Å; L215-V219 WeakPolarHBondContact O-CB 3.48Å; L215-V219 PolarHBondContact O-N 3.04Å; L215-V219 VanDerWaalsContact O-N 3.11Å; V219-L221 PolarHBondContact O-N 3.23Å; V219-L223 WeakPolarHBondContact O-CB 3.49Å; V219-L223 PolarHBondContact O-N 3.15Å
220	L	93.6	Very high	89.5	Confident	95 Å²	95	67.5 Å²	67.5	50%	0.497	40%	0.398	S	S	.	.	I	π-helix	trans	-67.9	-40.9	-172.3	-61.7	-177.6	0	0	0	112.5	L215 L223 G224	L215-L220 HydrophobicContact CD2-CD1 3.52Å; L215-L220 HydrophobicContact CD2-CD2 4.34Å; L215-L220 HydrophobicContact CD2-CG 3.73Å; L215-L220 PolarHBondContact O-N 3.29Å; L220-L223 PolarHBondContact O-N 3.2Å; L220-G224 PolarHBondContact O-N 3.15Å
221	L	91.4	Very high	89.1	Confident	56 Å²	56	71.9 Å²	71.9	29%	0.293	42%	0.422	S	S	.	.	H	α-helix	trans	-63.4	-54.2	-179.9	172.8	74.1	0	0	0	111.7	A216 V219 L223 G224 L225	A216-L221 WeakPolarHBondContact O-CB 3.31Å; A216-L221 PolarHBondContact O-N 3.04Å; V219-L221 PolarHBondContact O-N 3.23Å; L221-L223 VanDerWaalsContact C-N 3.35Å; L221-L223 PolarHBondContact O-N 3.17Å; L221-G224 PolarHBondContact O-N 3.41Å; L221-L225 HydrophobicContact CD1-CD1 4.22Å; L221-L225 HydrophobicContact CG-CD1 4.23Å; L221-L225 VanDerWaalsContact O-CG 3.29Å; L221-L225 WeakPolarHBondContact O-CG 3.41Å; L221-L225 PolarHBondContact O-N 2.93Å
222	P	88.6	Confident	88.5	Confident	47 Å²	47	74.1 Å²	74.1	31%	0.305	42%	0.424	S	S	.	.	H	α-helix	trans	-56.9	-46.5	173.7	-27.7	35.9	0	0	0	112.6	I217 F218 G224 L225 F226	I217-P222 VanDerWaalsContact O-CD 3.29Å; I217-P222 WeakPolarHBondContact O-CD 3.47Å; F218-P222 WeakPolarHBondContact O-CG 3.29Å; P222-G224 VanDerWaalsContact C-N 3.34Å; P222-G224 PolarHBondContact O-N 3.45Å; P222-L225 PolarHBondContact O-N 3.33Å; P222-F226 HydrophobicContact CB-CD2 4.5Å; P222-F226 HydrophobicContact CB-CE2 4.46Å; P222-F226 WeakPolarHBondContact O-CD2 3.46Å; P222-F226 PolarHBondContact O-N 3.29Å
223	L	89.8	Confident	87.8	Confident	115 Å²	115	78.2 Å²	78.2	60%	0.602	43%	0.434	S	S	*	.	H	α-helix	trans	-62.1	-41.8	-178.8	-173.5	63	0	0	0	112	V219 L220 L221 F226 G227	V219-L223 WeakPolarHBondContact O-CB 3.49Å; V219-L223 PolarHBondContact O-N 3.15Å; L220-L223 PolarHBondContact O-N 3.2Å; L221-L223 VanDerWaalsContact C-N 3.35Å; L221-L223 PolarHBondContact O-N 3.17Å; L223-F226 PolarHBondContact O-N 2.96Å; L223-G227 PolarHBondContact O-N 3.24Å
224	G	88.1	Confident	87	Confident	44 Å²	44	81.6 Å²	81.6	45%	0.454	46%	0.462	S	S	.	.	H	α-helix	trans	-63.4	-40.5	175.6	0	0	0	0	0	112.4	L220 L221 P222 A228	L220-G224 PolarHBondContact O-N 3.15Å; L221-G224 PolarHBondContact O-N 3.41Å; P222-G224 VanDerWaalsContact C-N 3.34Å; P222-G224 PolarHBondContact O-N 3.45Å; G224-A228 WeakPolarHBondContact O-CB 3.44Å; G224-A228 PolarHBondContact O-N 3.16Å
225	L	86.2	Confident	86.4	Confident	53 Å²	53	85.6 Å²	85.6	28%	0.277	48%	0.481	S	S	.	.	H	α-helix	trans	-66.1	-46.2	176.5	-70	168.3	0	0	0	112	A151 L221 P222 K229	A151-L225 HydrophobicContact CB-CD1 4.15Å; A151-L225 HydrophobicContact CB-CD2 4.44Å; L221-L225 HydrophobicContact CD1-CD1 4.22Å; L221-L225 HydrophobicContact CG-CD1 4.23Å; L221-L225 VanDerWaalsContact O-CG 3.29Å; L221-L225 WeakPolarHBondContact O-CG 3.41Å; L221-L225 PolarHBondContact O-N 2.93Å; P222-L225 PolarHBondContact O-N 3.33Å; L225-K229 WeakPolarHBondContact O-CB 3.24Å; L225-K229 PolarHBondContact O-N 3.1Å; L225-K229 VanDerWaalsContact O-N 3.07Å
226	F	85.5	Confident	85	Confident	156 Å²	156	84.6 Å²	84.6	68%	0.684	49%	0.492	S	S	*	.	H	α-helix	trans	-65.8	-43.1	176.3	-75.7	-66.2	0	0	0	111.9	P222 L223 K229 G230	P222-F226 HydrophobicContact CB-CD2 4.5Å; P222-F226 HydrophobicContact CB-CE2 4.46Å; P222-F226 WeakPolarHBondContact O-CD2 3.46Å; P222-F226 PolarHBondContact O-N 3.29Å; L223-F226 PolarHBondContact O-N 2.96Å; F226-K229 PolarHBondContact O-N 3.37Å; F226-G230 PolarHBondContact O-N 3.14Å
227	G	82.4	Confident	83.4	Confident	43 Å²	43	89 Å²	89	44%	0.443	51%	0.508	S	S	.	.	H	α-helix	trans	-61.2	-47.6	177	0	0	0	0	0	112.2	L223 K229 G230 L231	L223-G227 PolarHBondContact O-N 3.24Å; G227-K229 VanDerWaalsContact C-N 3.32Å; G227-K229 PolarHBondContact O-N 2.99Å; G227-G230 PolarHBondContact O-N 2.98Å; G227-L231 WeakPolarHBondContact O-CB 2.97Å; G227-L231 PolarHBondContact O-N 3.31Å
228	A	82.6	Confident	81.6	Confident	54 Å²	54	90.4 Å²	90.4	45%	0.446	53%	0.528	S	S	.	.	H	α-helix	trans	-61.8	-39.4	176.6	0	0	0	0	0	112.2	G224 K232	G224-A228 WeakPolarHBondContact O-CB 3.44Å; G224-A228 PolarHBondContact O-N 3.16Å; A228-K232 WeakPolarHBondContact O-CB 3.35Å; A228-K232 WeakPolarHBondContact O-CG 3.4Å; A228-K232 PolarHBondContact O-N 3Å
229	K	80.9	Confident	79.8	Confident	163 Å²	163	93 Å²	93	71%	0.709	55%	0.553	S	S	*	*	H	α-helix	trans	-68.4	-40.6	176.6	-165.8	175.3	-176	179.3	0	111.9	L225 F226 G227 K233	L225-K229 WeakPolarHBondContact O-CB 3.24Å; L225-K229 PolarHBondContact O-N 3.1Å; L225-K229 VanDerWaalsContact O-N 3.07Å; F226-K229 PolarHBondContact O-N 3.37Å; G227-K229 VanDerWaalsContact C-N 3.32Å; G227-K229 PolarHBondContact O-N 2.99Å; K229-K233 WeakPolarHBondContact O-CB 2.74Å; K229-K233 PolarHBondContact O-N 3.26Å; K229-K233 VanDerWaalsContact O-N 3.12Å
230	G	77.8	Confident	77.5	Confident	42 Å²	42	93.3 Å²	93.3	43%	0.433	56%	0.564	S	S	.	*	H	α-helix	trans	-63.6	-44.5	174.5	0	0	0	0	0	112.3	F226 G227 K233 A234	F226-G230 PolarHBondContact O-N 3.14Å; G227-G230 PolarHBondContact O-N 2.98Å; G230-K233 PolarHBondContact O-N 2.02Å; G230-A234 WeakPolarHBondContact O-CB 3.18Å; G230-A234 PolarHBondContact O-N 3.47Å
231	L	81.1	Confident	74.8	Confident	105 Å²	105	95 Å²	95	55%	0.55	58%	0.581	S	S	.	*	H	α-helix	trans	-64.1	-45.6	177.6	-176.6	61.9	0	0	0	111.9	G227 K233 A234 L235	G227-L231 WeakPolarHBondContact O-CB 2.97Å; G227-L231 PolarHBondContact O-N 3.31Å; L231-K233 VanDerWaalsContact C-N 3.27Å; L231-K233 PolarHBondContact O-N 3.44Å; L231-A234 PolarHBondContact O-N 3.29Å; L231-L235 HydrophobicContact CD1-CD1 3.86Å; L231-L235 HydrophobicContact CD1-CG 4.04Å; L231-L235 HydrophobicContact CD2-CD1 4.49Å; L231-L235 HydrophobicContact CG-CD1 3.8Å; L231-L235 HydrophobicContact CG-CG 4.37Å; L231-L235 WeakPolarHBondContact O-CB 3.36Å; L231-L235 WeakPolarHBondContact O-CG 3.36Å; L231-L235 PolarHBondContact O-N 3.1Å
232	K	77.9	Confident	72.2	Confident	134 Å²	134	99.6 Å²	99.6	58%	0.583	64%	0.642	S	S	*	*	H	α-helix	trans	-57.3	-41.1	174.1	-79.7	-175.7	176.6	-173.4	0	112.2	A228 M237	A228-K232 WeakPolarHBondContact O-CB 3.35Å; A228-K232 WeakPolarHBondContact O-CG 3.4Å; A228-K232 PolarHBondContact O-N 3Å; K232-M237 PolarHBondContact O-N 2.81Å
233	K	77.8	Confident	71.4	Confident	184 Å²	184	102.3 Å²	102.3	80%	0.8	66%	0.658	S	S	*	*	H	α-helix	trans	-67.7	-41.1	177.1	-172.2	176.2	-180	-177.8	0	112.2	K229 G230 L231 G236	K229-K233 WeakPolarHBondContact O-CB 2.74Å; K229-K233 PolarHBondContact O-N 3.26Å; K229-K233 VanDerWaalsContact O-N 3.12Å; G230-K233 PolarHBondContact O-N 2.02Å; L231-K233 VanDerWaalsContact C-N 3.27Å; L231-K233 PolarHBondContact O-N 3.44Å; K233-G236 PolarHBondContact O-N 3.38Å
234	A	77.1	Confident	70.4	Confident	86 Å²	86	101.6 Å²	101.6	71%	0.711	66%	0.661	S	S	*	*	H	α-helix	trans	-69.1	-35.1	179	0	0	0	0	0	112.9	G230 L231 G236	G230-A234 WeakPolarHBondContact O-CB 3.18Å; G230-A234 PolarHBondContact O-N 3.47Å; L231-A234 PolarHBondContact O-N 3.29Å; A234-G236 PolarHBondContact O-N 3.02Å
235	L	80.6	Confident	69.4	Low	110 Å²	110	104.8 Å²	104.8	58%	0.576	67%	0.673	S	S	*	*	T	Hydrogen-bonded Turn	trans	-77.8	2.8	177.3	-68.4	172.7	0	0	0	113.7	L231 M237	L231-L235 HydrophobicContact CD1-CD1 3.86Å; L231-L235 HydrophobicContact CD1-CG 4.04Å; L231-L235 HydrophobicContact CD2-CD1 4.49Å; L231-L235 HydrophobicContact CG-CD1 3.8Å; L231-L235 HydrophobicContact CG-CG 4.37Å; L231-L235 WeakPolarHBondContact O-CB 3.36Å; L231-L235 WeakPolarHBondContact O-CG 3.36Å; L231-L235 PolarHBondContact O-N 3.1Å; L235-M237 HydrophobicContact CB-SD 4.5Å; L235-M237 PolarHBondContact O-N 3.22Å
236	G	65.1	Low	68.4	Low	67 Å²	67	107.8 Å²	107.8	69%	0.691	70%	0.696	S	S	*	*	T	Hydrogen-bonded Turn	trans	65	9.6	-179.3	0	0	0	0	0	114.4	K233 A234 G238	K233-G236 PolarHBondContact O-N 3.38Å; A234-G236 PolarHBondContact O-N 3.02Å; G236-G238 PolarHBondContact O-N 3.24Å
237	M	62.1	Low	67.4	Low	130 Å²	130	104.8 Å²	104.8	64%	0.64	70%	0.697	S	S	*	*			trans	-74.5	83.1	172.7	-75.4	168.3	75.5	0	0	108	K232 L235	K232-M237 PolarHBondContact O-N 2.81Å; L235-M237 HydrophobicContact CB-SD 4.5Å; L235-M237 PolarHBondContact O-N 3.22Å
238	G	58.2	Low	66.4	Low	53 Å²	53	108.9 Å²	108.9	55%	0.546	71%	0.714	S	S	.	*	P	Polyproline II helix	trans	-55.2	163.4	168.5	0	0	0	0	0	111.5	G236 A240	G236-G238 PolarHBondContact O-N 3.24Å; G238-A240 PolarHBondContact O-N 2.72Å; G238-A240 VanDerWaalsContact O-N 3.13Å
239	P	55.4	Low	65.2	Low	135 Å²	135	112.9 Å²	112.9	88%	0.877	73%	0.733	S	S	*	*	P	Polyproline II helix	trans	-52.8	125.3	174.2	22.9	-30.5	0	0	0	108.7
240	A	45.2	Very low	64	Low	88 Å²	88	109 Å²	109	73%	0.727	74%	0.735	S	S	*	*	P	Polyproline II helix	trans	-53.4	139.4	176.7	0	0	0	0	0	109.3	G238 G242	G238-A240 PolarHBondContact O-N 2.72Å; G238-A240 VanDerWaalsContact O-N 3.13Å; A240-G242 PolarHBondContact O-N 3.02Å
241	P	37.7	Very low	62.9	Low	131 Å²	131	114.6 Å²	114.6	85%	0.851	76%	0.76	S	S	*	*	P	Polyproline II helix	trans	-58.6	131.3	179.1	23.9	-31.5	0	0	0	109.5
242	G	36.3	Very low	61.2	Low	152 Å²	152	115.5 Å²	115.5	100%	1.567	78%	0.779	S	S	*	*			trans	-77.9	0	172.3	0	0	0	0	0	112.5	A240	A240-G242 PolarHBondContact O-N 3.02Å

Retrieved 242 of 242 residues in 337.2 ms (Link to these results)

U.S. Privacy Notice - Disclaimer / Registrations / Copyright Statement - Linking Policy - Notice of Privacy Practices (HIPAA) - Notice of Non‑Discrimination
© Copyright 2026 St. Jude Children's Research Hospital, a not-for-profit, section 501(c)(3).