A0A060VCX0_HUMAN Loading...

MHC class I antigen

AlphaFold DB , UniProt , Accession A0A060VCX0, Species HUMAN (Homo sapiens, Human), Gene HLA-A, Length 340 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1S93.8Very high98.1Very high96 Ų9637 Ų3767%0.67120%0.202SC*.  0156.40-590000107.8V102S1-V102 CarbonylContact C-O 3.54Å; S1-V102 WeakPolarHBondContact CA-O 3.36Å; S1-V102 WeakPolarHBondContact CB-O 3.43Å
2H97.4Very high98Very high43 Ų4335.3 Ų35.320%0.19919%0.194CC..EExtended strand (participates in β ladder)trans-138.4160.6-178.5-65.6-76.7000111D28 D101 V102 L167 L171H2-D28 WeakPolarHBondContact CA-OD1 3.26Å; H2-D28 IonicContact CE1-OD2 3.51Å; H2-D28 IonicContact CG-OD2 3.58Å; H2-D28 IonicContact ND1-OD1 2.74Å; H2-D28 IonicContact ND1-OD2 3.42Å; H2-D28 PolarHBondContact ND1-OD2 3.25Å; H2-D101 CarbonylContact O-C 3.59Å; H2-D101 WeakPolarHBondContact O-CA 3.38Å; H2-V102 HydrophobicContact CB-CG2 4.01Å; H2-V102 PolarHBondContact N-O 3.43Å; H2-V102 PolarHBondContact O-N 2.83Å; H2-L167 HydrophobicContact CB-CD1 4.4Å; H2-L171 HydrophobicContact CB-CD1 3.68Å; H2-L171 HydrophobicContact CB-CD2 3.99Å; H2-L171 HydrophobicContact CB-CG 4.41Å; H2-L171 WeakPolarHBondContact ND1-CD2 3.28Å
3S98.3Very high97.9Very high22 Ų2237.7 Ų37.715%0.15420%0.199CC..EExtended strand (participates in β ladder)trans-136.1151.317966.90000111.9V27 D28 C100 D101S3-V27 CarbonylContact O-C 3.46Å; S3-V27 VanDerWaalsContact O-CA 3.32Å; S3-V27 WeakPolarHBondContact O-CA 3.29Å; S3-D28 PolarHBondContact N-OD1 3.5Å; S3-D28 PolarHBondContact O-N 2.92Å; S3-D28 PolarHBondContact OG-OD1 2.9Å; S3-C100 WeakPolarHBondContact CA-O 3.46Å; S3-D101 WeakPolarHBondContact CB-OD1 3.5Å
4M98.7Very high97.4Very high0 Ų038.6 Ų38.60%021%0.208CC..EExtended strand (participates in β ladder)trans-124123165.8-177.4175.460.300108.4Y6 Y26 V27 F32 G99 C100 C163 W166 L167 Y170M4-Y6 HydrophobicContact CE-CE2 4.06Å; M4-Y6 HydrophobicContact CG-CE2 4.01Å; M4-Y6 HydrophobicContact SD-CE2 3.86Å; M4-Y26 CarbonylContact C-O 3.6Å; M4-Y26 WeakPolarHBondContact CA-O 3.31Å; M4-V27 HydrophobicContact CG-CG2 4.36Å; M4-F32 HydrophobicContact CG-CE1 4.38Å; M4-F32 HydrophobicContact CG-CZ 4.5Å; M4-F32 HydrophobicContact SD-CZ 4.26Å; M4-G99 CarbonylContact O-C 3.51Å; M4-G99 WeakPolarHBondContact O-CA 3.27Å; M4-C100 PolarHBondContact N-O 3Å; M4-C100 PolarHBondContact O-N 3.42Å; M4-C163 HydrophobicContact CE-CB 4.16Å; M4-C163 VanDerWaalsContact CE-O 3.23Å; M4-C163 WeakPolarHBondContact CE-O 3.3Å; M4-C163 WeakPolarHBondContact CE-SG 3.44Å; M4-W166 HydrophobicContact CE-CB 4.01Å; M4-W166 HydrophobicContact SD-CB 4.32Å; M4-L167 HydrophobicContact CB-CB 4.07Å; M4-L167 HydrophobicContact CB-CD1 4.01Å; M4-L167 HydrophobicContact CB-CD2 4.16Å; M4-L167 HydrophobicContact CB-CG 4.3Å; M4-Y170 HydrophobicContact SD-CD2 3.79Å; M4-Y170 HydrophobicContact SD-CE2 3.57Å; M4-Y170 VanDerWaalsContact SD-CE2 3.57Å
5R98.7Very high96.9Very high50 Ų5042 Ų4219%0.18926%0.256CS..EExtended strand (participates in β ladder)trans-129.4137.2-177.5-55.6-61.3179.276.95.1111F7 G25 Y26 Y98 D101 Y112R5-F7 HydrophobicContact CB-CD2 4.48Å; R5-F7 HydrophobicContact CB-CE2 3.66Å; R5-F7 HydrophobicContact CB-CZ 4.04Å; R5-G25 CarbonylContact O-C 3.58Å; R5-G25 WeakPolarHBondContact O-CA 3.48Å; R5-Y26 PolarHBondContact N-O 3.37Å; R5-Y26 PolarHBondContact O-N 2.97Å; R5-Y98 WeakPolarHBondContact CA-O 3.3Å; R5-D101 IonicContact CZ-OD1 3.4Å; R5-D101 IonicContact NE-OD1 3.71Å; R5-D101 PolarHBondContact NE-OD1 3.43Å; R5-D101 VanDerWaalsContact NH2-CG 3.29Å; R5-D101 IonicContact NH2-OD1 3.12Å; R5-D101 PolarHBondContact NH2-OD1 3.12Å; R5-D101 IonicContact NH2-OD2 2.72Å; R5-D101 PolarHBondContact NH2-OD2 3.15Å; R5-D101 VanDerWaalsContact NH2-OD2 3.07Å; R5-Y112 VanDerWaalsContact NH2-CZ 3.32Å; R5-Y112 PolarHBondContact NH2-OH 2.92Å
6Y98.8Very high96.6Very high10 Ų1052.7 Ų52.74%0.03929%0.29CS..EExtended strand (participates in β ladder)trans-114.4137.8170.4-68.9-89.2000109.7M4 Y8 V24 F32 V33 M97 Y98M4-Y6 HydrophobicContact CE-CE2 4.06Å; M4-Y6 HydrophobicContact CG-CE2 4.01Å; M4-Y6 HydrophobicContact SD-CE2 3.86Å; Y6-Y8 HydrophobicContact CD1-CE1 4.35Å; Y6-V24 CarbonylContact C-O 3.56Å; Y6-V24 WeakPolarHBondContact CA-O 3.33Å; Y6-F32 AromaticContact CE1-CZ 3.9Å; Y6-F32 HydrophobicContact CE1-CZ 3.9Å; Y6-F32 AromaticContact CZ-CZ 3.7Å; Y6-F32 WeakPolarHBondContact OH-CZ 3.1Å; Y6-V33 HydrophobicContact CE1-CG2 3.96Å; Y6-M97 WeakPolarHBondContact O-CA 3.4Å; Y6-Y98 VanDerWaalsContact CB-CZ 3.47Å; Y6-Y98 HydrophobicContact CD2-CD2 4.3Å; Y6-Y98 AromaticContact CD2-CE2 3.46Å; Y6-Y98 HydrophobicContact CD2-CE2 3.46Å; Y6-Y98 VanDerWaalsContact CD2-CE2 3.46Å; Y6-Y98 AromaticContact CD2-CZ 3.63Å; Y6-Y98 WeakPolarHBondContact CD2-OH 3.39Å; Y6-Y98 HydrophobicContact CE2-CE2 4.24Å; Y6-Y98 HydrophobicContact CG-CE1 4.31Å; Y6-Y98 AromaticContact CG-CE2 3.99Å; Y6-Y98 HydrophobicContact CG-CE2 3.99Å; Y6-Y98 AromaticContact CG-CZ 3.67Å; Y6-Y98 PolarHBondContact N-O 3.19Å; Y6-Y98 PolarHBondContact O-N 3.16Å; Y6-Y98 VanDerWaalsContact O-N 3.1Å
7F98.8Very high96.2Very high87 Ų8753.1 Ų53.138%0.38231%0.309SS..EExtended strand (participates in β ladder)trans-124.5119.4177.9-57.7-96.9000109.4R5 A23 V24 Y26 R96 M97R5-F7 HydrophobicContact CB-CD2 4.48Å; R5-F7 HydrophobicContact CB-CE2 3.66Å; R5-F7 HydrophobicContact CB-CZ 4.04Å; F7-A23 WeakPolarHBondContact O-CA 3.44Å; F7-V24 HydrophobicContact CB-CG2 3.81Å; F7-V24 HydrophobicContact CD2-CG2 4.32Å; F7-V24 PolarHBondContact N-O 3.41Å; F7-V24 PolarHBondContact O-N 3.48Å; F7-Y26 HydrophobicContact CD2-CD2 4.2Å; F7-Y26 HydrophobicContact CE2-CD2 4.26Å; F7-R96 CarbonylContact C-O 3.58Å; F7-R96 WeakPolarHBondContact CA-O 3.28Å; F7-M97 HydrophobicContact CD1-CB 3.93Å; F7-M97 HydrophobicContact CD1-CG 3.6Å; F7-M97 HydrophobicContact CE1-CB 4.03Å; F7-M97 HydrophobicContact CE1-CG 3.29Å; F7-M97 HydrophobicContact CG-CG 4.41Å; F7-M97 HydrophobicContact CZ-CG 3.86Å
8Y98.7Very high96.1Very high8 Ų855.1 Ų55.13%0.03132%0.315CS..EExtended strand (participates in β ladder)trans-110.9142.6177-58.4-9.1000109.2Y6 F21 I22 A23 H69 Q95 R96 Y98Y6-Y8 HydrophobicContact CD1-CE1 4.35Å; Y8-F21 HydrophobicContact CD1-CZ 4.39Å; Y8-F21 HydrophobicContact CD2-CE2 4.28Å; Y8-F21 AromaticContact CD2-CZ 3.85Å; Y8-F21 HydrophobicContact CD2-CZ 3.85Å; Y8-F21 HydrophobicContact CE2-CZ 4.39Å; Y8-F21 HydrophobicContact CG-CE2 4.31Å; Y8-F21 AromaticContact CG-CZ 3.83Å; Y8-F21 HydrophobicContact CG-CZ 3.83Å; Y8-I22 CarbonylContact C-O 3.59Å; Y8-I22 WeakPolarHBondContact CA-O 3.47Å; Y8-A23 HydrophobicContact CD1-CB 3.29Å; Y8-A23 HydrophobicContact CE1-CB 3.47Å; Y8-A23 VanDerWaalsContact CE1-CB 3.47Å; Y8-A23 HydrophobicContact CG-CB 4.13Å; Y8-H69 HydrophobicContact CD2-CB 4.43Å; Y8-H69 HydrophobicContact CE2-CB 4.2Å; Y8-H69 AromaticContact CE2-CD2 3.87Å; Y8-H69 AromaticContact CE2-CG 3.9Å; Y8-Q95 WeakPolarHBondContact O-CA 3.48Å; Y8-R96 PolarHBondContact N-O 2.96Å; Y8-R96 PolarHBondContact O-N 3.46Å; Y8-Y98 HydrophobicContact CD2-CE1 4.42Å; Y8-Y98 HydrophobicContact CE1-CE1 4.17Å; Y8-Y98 AromaticContact CE2-CE1 3.8Å; Y8-Y98 HydrophobicContact CE2-CE1 3.8Å; Y8-Y98 AromaticContact CZ-CE1 3.66Å; Y8-Y98 PolarHBondContact OH-OH 3.24Å
9T98.8Very high96.1Very high43 Ų4353.4 Ų53.426%0.26431%0.306SS..EExtended strand (participates in β ladder)trans-140.6124.9177.6-57.10000109.7V11 F21 I22 T93 I94 Q95T9-V11 HydrophobicContact CG2-CG2 4.09Å; T9-F21 WeakPolarHBondContact O-CA 3.5Å; T9-I22 PolarHBondContact N-O 3.14Å; T9-I22 PolarHBondContact O-N 3.29Å; T9-T93 HydrophobicContact CG2-CG2 3.9Å; T9-I94 WeakPolarHBondContact CA-O 3.41Å; T9-Q95 HydrophobicContact CG2-CG 4.08Å
10S98.6Very high96.2Very high2 Ų255.3 Ų55.31%0.01431%0.308CS..EExtended strand (participates in β ladder)trans-119.4119.7179.2-70.80000109.8R20 F21 D73 T93 I94S10-R20 CarbonylContact C-O 3.52Å; S10-R20 VanDerWaalsContact CA-O 3.3Å; S10-R20 WeakPolarHBondContact CA-O 3.39Å; S10-F21 WeakPolarHBondContact OG-CD2 3.42Å; S10-D73 WeakPolarHBondContact OG-CB 3.37Å; S10-D73 PolarHBondContact OG-OD2 3.32Å; S10-T93 CarbonylContact O-C 3.57Å; S10-T93 VanDerWaalsContact O-CA 3.27Å; S10-T93 WeakPolarHBondContact O-CA 3.31Å; S10-I94 PolarHBondContact N-O 3.2Å; S10-I94 PolarHBondContact O-N 2.99Å
11V98.4Very high96.3Very high46 Ų4652.6 Ų52.628%0.27929%0.293SS..EExtended strand (participates in β ladder)trans-116.7116-178.5-174.50000109.3T9 P19 R20 H92 T93T9-V11 HydrophobicContact CG2-CG2 4.09Å; V11-P19 CarbonylContact O-C 3.51Å; V11-P19 WeakPolarHBondContact O-CA 3.3Å; V11-P19 WeakPolarHBondContact O-CB 3.32Å; V11-R20 PolarHBondContact N-O 2.91Å; V11-R20 PolarHBondContact O-N 3.39Å; V11-H92 WeakPolarHBondContact CA-O 3.41Å; V11-T93 HydrophobicContact CG2-CG2 4.13Å
12S97.4Very high96.6Very high16 Ų1650 Ų5011%0.11227%0.271CS..  trans-68.4146.1174.976.60000110.8S91 H92S12-S91 PolarHBondContact O-OG 2.83Å; S12-S91 WeakPolarHBondContact OG-CA 3.41Å; S12-H92 PolarHBondContact N-O 2.62Å; S12-H92 PolarHBondContact OG-N 2.96Å; S12-H92 PolarHBondContact OG-O 2.94Å
13R95.8Very high96.6Very high67 Ų6748 Ų4825%0.25326%0.262SS..  trans-131.871.4-176.1-61.7-174.9-75.8-162.2-10.2110.7G15 R16 E18 D38R13-G15 PolarHBondContact O-N 2.92Å; R13-R16 HydrophobicContact CB-CB 4.08Å; R13-R16 PolarHBondContact O-N 3.34Å; R13-E18 PolarHBondContact NE-O 3.48Å; R13-E18 PolarHBondContact NH2-O 3.42Å; R13-D38 IonicContact CZ-OD1 3.53Å; R13-D38 IonicContact CZ-OD2 3.65Å; R13-D38 IonicContact NH1-OD1 3.01Å; R13-D38 PolarHBondContact NH1-OD1 3.29Å; R13-D38 IonicContact NH1-OD2 3.08Å; R13-D38 PolarHBondContact NH1-OD2 3.43Å; R13-D38 IonicContact NH2-OD1 2.84Å; R13-D38 PolarHBondContact NH2-OD1 3.48Å; R13-D38 IonicContact NH2-OD2 3.73Å
14P91.3Very high96.7Very high51 Ų5148 Ų4833%0.33126%0.261SS..THydrogen-bonded Turntrans-49.6129.1-179-25.533.5000111.8R16 E88 G90P14-R16 PolarHBondContact O-N 3.44Å; P14-R16 VanDerWaalsContact O-N 3.15Å; P14-E88 WeakPolarHBondContact CB-O 3.37Å; P14-E88 WeakPolarHBondContact CG-O 3.47Å; P14-G90 WeakPolarHBondContact CG-O 3.47Å
15G89.6Confident96.7Very high89 Ų8948 Ų4892%0.91826%0.261SS*.THydrogen-bonded Turntrans69.13.6-178.500000116.2R13R13-G15 PolarHBondContact O-N 2.92Å
16R91.9Very high96.7Very high213 Ų21348.9 Ų48.980%0.80427%0.265SS*.SBendtrans-126.623.4-177.3-59.2-178.6-176.1-178.51.5113.3R13 P14R13-R16 HydrophobicContact CB-CB 4.08Å; R13-R16 PolarHBondContact O-N 3.34Å; P14-R16 PolarHBondContact O-N 3.44Å; P14-R16 VanDerWaalsContact O-N 3.15Å
17G91.2Very high96.6Very high59 Ų5948.4 Ų48.461%0.60826%0.263SS*.SBendtrans95.4-157.2176.500000113.9
18E93.9Very high96.5Very high90 Ų9045.7 Ų45.742%0.42125%0.253SS..SBendtrans-68.5154-176.4-64.5-59.8165.200112.7R13 R20 R74R13-E18 PolarHBondContact NE-O 3.48Å; R13-E18 PolarHBondContact NH2-O 3.42Å; E18-R20 PolarHBondContact O-N 2.88Å; E18-R74 IonicContact OE1-CZ 3.76Å; E18-R74 IonicContact OE1-NE 3.01Å; E18-R74 IonicContact OE1-NH1 2.7Å; E18-R74 PolarHBondContact OE1-NH1 3.32Å; E18-R74 IonicContact OE1-NH2 3.14Å; E18-R74 PolarHBondContact OE1-NH2 3.38Å; E18-R74 WeakPolarHBondContact OE2-CD 3.34Å; E18-R74 IonicContact OE2-CZ 2.71Å; E18-R74 IonicContact OE2-NE 3.67Å; E18-R74 PolarHBondContact OE2-NE 3.49Å; E18-R74 IonicContact OE2-NH1 3.02Å; E18-R74 PolarHBondContact OE2-NH1 2.89Å; E18-R74 IonicContact OE2-NH2 3.72Å; E18-R74 PolarHBondContact OE2-NH2 2.9Å; E18-R74 VanDerWaalsContact OE2-NH2 3.08Å
19P96.6Very high96.3Very high23 Ų2348.5 Ų48.515%0.14927%0.268CS..PPolyproline II helixtrans-52.9139171-25.234.9000111.8V11 R74 L77V11-P19 CarbonylContact O-C 3.51Å; V11-P19 WeakPolarHBondContact O-CA 3.3Å; V11-P19 WeakPolarHBondContact O-CB 3.32Å; P19-R74 HydrophobicContact CG-CB 4.35Å; P19-R74 HydrophobicContact CG-CG 4.17Å; P19-L77 HydrophobicContact CB-CD1 3.62Å; P19-L77 HydrophobicContact CG-CD1 3.64Å
20R98Very high96.2Very high90 Ų9047.5 Ų47.534%0.3426%0.262SS..EExtended strand (participates in β ladder)trans-78.3128.4171.7-171176179.1-176.8-2.3108.5S10 V11 E18 I22 D36 D38S10-R20 CarbonylContact C-O 3.52Å; S10-R20 VanDerWaalsContact CA-O 3.3Å; S10-R20 WeakPolarHBondContact CA-O 3.39Å; V11-R20 PolarHBondContact N-O 2.91Å; V11-R20 PolarHBondContact O-N 3.39Å; E18-R20 PolarHBondContact O-N 2.88Å; R20-I22 HydrophobicContact CG-CG1 4.36Å; R20-D36 IonicContact CZ-OD1 3.76Å; R20-D36 IonicContact CZ-OD2 3.66Å; R20-D36 IonicContact NE-OD1 2.71Å; R20-D36 PolarHBondContact NE-OD1 3.3Å; R20-D36 VanDerWaalsContact NE-OD1 3.14Å; R20-D36 IonicContact NE-OD2 3.52Å; R20-D36 IonicContact NH2-OD1 3.51Å; R20-D36 IonicContact NH2-OD2 2.73Å; R20-D36 PolarHBondContact NH2-OD2 2.9Å; R20-D38 VanDerWaalsContact CD-OD2 3.29Å; R20-D38 WeakPolarHBondContact CD-OD2 3.43Å; R20-D38 IonicContact NE-OD2 2.78Å
21F98.6Very high96.1Very high0 Ų049.8 Ų49.80%027%0.273CS..EExtended strand (participates in β ladder)trans-114.2125.6175.8179-86.5000110Y8 T9 S10 A23 F35 S37 V66 H69 S70Y8-F21 HydrophobicContact CD1-CZ 4.39Å; Y8-F21 HydrophobicContact CD2-CE2 4.28Å; Y8-F21 AromaticContact CD2-CZ 3.85Å; Y8-F21 HydrophobicContact CD2-CZ 3.85Å; Y8-F21 HydrophobicContact CE2-CZ 4.39Å; Y8-F21 HydrophobicContact CG-CE2 4.31Å; Y8-F21 AromaticContact CG-CZ 3.83Å; Y8-F21 HydrophobicContact CG-CZ 3.83Å; T9-F21 WeakPolarHBondContact O-CA 3.5Å; S10-F21 WeakPolarHBondContact OG-CD2 3.42Å; F21-A23 HydrophobicContact CE1-CB 3.61Å; F21-A23 HydrophobicContact CZ-CB 3.99Å; F21-F35 AromaticContact CD1-CD1 3.66Å; F21-F35 HydrophobicContact CD1-CD1 3.66Å; F21-F35 AromaticContact CD1-CE1 3.75Å; F21-F35 HydrophobicContact CD1-CE1 3.75Å; F21-F35 AromaticContact CE1-CD1 3.98Å; F21-F35 HydrophobicContact CE1-CD1 3.98Å; F21-F35 HydrophobicContact CE1-CE1 4.35Å; F21-S37 PolarHBondContact N-OG 3.02Å; F21-S37 PolarHBondContact O-N 3.43Å; F21-S37 PolarHBondContact O-OG 3.49Å; F21-V66 HydrophobicContact CE1-CB 4.12Å; F21-H69 HydrophobicContact CE2-CB 4.42Å; F21-H69 HydrophobicContact CZ-CB 4.24Å; F21-S70 WeakPolarHBondContact CB-OG 3.38Å; F21-S70 VanDerWaalsContact CG-CB 3.5Å
22I98.7Very high96.1Very high40 Ų4047.6 Ų47.621%0.20526%0.259CS..EExtended strand (participates in β ladder)trans-122.7132.2174-58.6174000107.8Y8 T9 R20 V24 F35Y8-I22 CarbonylContact C-O 3.59Å; Y8-I22 WeakPolarHBondContact CA-O 3.47Å; T9-I22 PolarHBondContact N-O 3.14Å; T9-I22 PolarHBondContact O-N 3.29Å; R20-I22 HydrophobicContact CG-CG1 4.36Å; I22-V24 HydrophobicContact CG2-CG1 4.35Å; I22-F35 WeakPolarHBondContact CA-O 3.28Å
23A98.8Very high96.2Very high1 Ų146.9 Ų46.91%0.00825%0.254CS..EExtended strand (participates in β ladder)trans-125.2136.9171.100000110.1F7 Y8 F21 R34 F35 V66F7-A23 WeakPolarHBondContact O-CA 3.44Å; Y8-A23 HydrophobicContact CD1-CB 3.29Å; Y8-A23 HydrophobicContact CE1-CB 3.47Å; Y8-A23 VanDerWaalsContact CE1-CB 3.47Å; Y8-A23 HydrophobicContact CG-CB 4.13Å; F21-A23 HydrophobicContact CE1-CB 3.61Å; F21-A23 HydrophobicContact CZ-CB 3.99Å; A23-R34 CarbonylContact O-C 3.58Å; A23-R34 VanDerWaalsContact O-CA 3.31Å; A23-R34 WeakPolarHBondContact O-CA 3.31Å; A23-F35 HydrophobicContact CB-CB 4.27Å; A23-F35 PolarHBondContact N-O 3.38Å; A23-F35 PolarHBondContact O-N 3Å; A23-V66 HydrophobicContact CB-CG1 4.22Å
24V98.8Very high96.3Very high22 Ų2246.8 Ų46.813%0.13325%0.254CS..EExtended strand (participates in β ladder)trans-132.9146.9174.4-62.40000110Y6 F7 I22 Y26 Q31 V33 R34Y6-V24 CarbonylContact C-O 3.56Å; Y6-V24 WeakPolarHBondContact CA-O 3.33Å; F7-V24 HydrophobicContact CB-CG2 3.81Å; F7-V24 HydrophobicContact CD2-CG2 4.32Å; F7-V24 PolarHBondContact N-O 3.41Å; F7-V24 PolarHBondContact O-N 3.48Å; I22-V24 HydrophobicContact CG2-CG1 4.35Å; V24-Y26 HydrophobicContact CB-CE2 4.05Å; V24-Y26 HydrophobicContact CG2-CD2 4.34Å; V24-Y26 HydrophobicContact CG2-CE2 3.79Å; V24-Q31 VanDerWaalsContact CG1-NE2 3.26Å; V24-V33 WeakPolarHBondContact CA-O 3.4Å; V24-R34 HydrophobicContact CG1-CB 4.49Å; V24-R34 HydrophobicContact CG1-CG 4.19Å
25G98.6Very high96.6Very high0 Ų044.6 Ų44.60%024%0.239CC..EExtended strand (participates in β ladder)trans-125.1138.4175.900000110.6R5 Q31 F32 V33R5-G25 CarbonylContact O-C 3.58Å; R5-G25 WeakPolarHBondContact O-CA 3.48Å; G25-Q31 WeakPolarHBondContact O-CA 3.44Å; G25-F32 WeakPolarHBondContact O-CD1 3.34Å; G25-F32 PolarHBondContact O-N 2.92Å; G25-V33 PolarHBondContact N-O 3.37Å; G25-V33 VanDerWaalsContact N-O 3.07Å; G25-V33 PolarHBondContact O-N 3.04Å
26Y98.6Very high97.1Very high69 Ų6941.4 Ų41.427%0.27120%0.201SC..EExtended strand (participates in β ladder)trans-125.2141.7178.7-73.8-102.1000110.4M4 R5 F7 V24 T30 Q31M4-Y26 CarbonylContact C-O 3.6Å; M4-Y26 WeakPolarHBondContact CA-O 3.31Å; R5-Y26 PolarHBondContact N-O 3.37Å; R5-Y26 PolarHBondContact O-N 2.97Å; F7-Y26 HydrophobicContact CD2-CD2 4.2Å; F7-Y26 HydrophobicContact CE2-CD2 4.26Å; V24-Y26 HydrophobicContact CB-CE2 4.05Å; V24-Y26 HydrophobicContact CG2-CD2 4.34Å; V24-Y26 HydrophobicContact CG2-CE2 3.79Å; Y26-T30 WeakPolarHBondContact CA-O 3.28Å; Y26-T30 VanDerWaalsContact CD1-C 3.47Å; Y26-Q31 HydrophobicContact CD1-CB 3.97Å; Y26-Q31 VanDerWaalsContact CD1-N 3.29Å; Y26-Q31 HydrophobicContact CD2-CG 4.41Å; Y26-Q31 HydrophobicContact CE1-CB 3.48Å; Y26-Q31 VanDerWaalsContact CE1-CB 3.48Å; Y26-Q31 HydrophobicContact CE1-CG 4.17Å; Y26-Q31 HydrophobicContact CE2-CB 4.16Å; Y26-Q31 HydrophobicContact CE2-CG 3.91Å; Y26-Q31 HydrophobicContact CG-CB 4.49Å
27V98.4Very high97.4Very high0 Ų032 Ų320%017%0.168CC..EExtended strand (participates in β ladder)trans-109.3119.8157.3176.40000105.9S3 M4 D29 T30 F32 W50 L167 Y170 L171 L178S3-V27 CarbonylContact O-C 3.46Å; S3-V27 VanDerWaalsContact O-CA 3.32Å; S3-V27 WeakPolarHBondContact O-CA 3.29Å; M4-V27 HydrophobicContact CG-CG2 4.36Å; V27-D29 PolarHBondContact O-N 3.5Å; V27-T30 PolarHBondContact N-O 3.43Å; V27-T30 PolarHBondContact O-N 3.3Å; V27-F32 HydrophobicContact CG2-CD1 3.97Å; V27-F32 HydrophobicContact CG2-CE1 3.99Å; V27-W50 HydrophobicContact CB-CH2 4.43Å; V27-W50 HydrophobicContact CG2-CH2 3.95Å; V27-L167 HydrophobicContact CG1-CD1 3.63Å; V27-L167 HydrophobicContact CG2-CD1 4.3Å; V27-Y170 HydrophobicContact CG2-CD2 3.93Å; V27-Y170 HydrophobicContact CG2-CG 4.45Å; V27-L171 HydrophobicContact CG1-CD2 4.07Å; V27-L178 HydrophobicContact CB-CD1 4.28Å; V27-L178 HydrophobicContact CB-CD2 4.11Å; V27-L178 HydrophobicContact CG1-CD1 3.89Å; V27-L178 HydrophobicContact CG1-CD2 4.07Å
28D96.3Very high97.6Very high31 Ų3132.9 Ų32.917%0.16616%0.159CC..THydrogen-bonded Turntrans48-123.6-165.6-53.4-40.6000110.4H2 S3H2-D28 WeakPolarHBondContact CA-OD1 3.26Å; H2-D28 IonicContact CE1-OD2 3.51Å; H2-D28 IonicContact CG-OD2 3.58Å; H2-D28 IonicContact ND1-OD1 2.74Å; H2-D28 IonicContact ND1-OD2 3.42Å; H2-D28 PolarHBondContact ND1-OD2 3.25Å; S3-D28 PolarHBondContact N-OD1 3.5Å; S3-D28 PolarHBondContact O-N 2.92Å; S3-D28 PolarHBondContact OG-OD1 2.9Å
29D94.6Very high97.8Very high67 Ų6730.1 Ų30.136%0.35815%0.151SC..THydrogen-bonded Turntrans-93.48-179.9-51.3-58.2000113.5V27 A210 F240V27-D29 PolarHBondContact O-N 3.5Å; D29-A210 HydrophobicContact CB-CB 4.16Å; D29-A210 VanDerWaalsContact CG-CB 3.48Å; D29-A210 VanDerWaalsContact OD2-CB 3.31Å; D29-A210 WeakPolarHBondContact OD2-CB 3.46Å; D29-A210 PolarHBondContact OD2-N 3.01Å; D29-F240 HydrophobicContact CB-CE2 3.82Å; D29-F240 HydrophobicContact CB-CZ 3.5Å; D29-F240 VanDerWaalsContact CB-CZ 3.5Å
30T95.9Very high97.8Very high22 Ų2234.5 Ų34.514%0.13519%0.189CC..EExtended strand (participates in β ladder)trans-105.1115.2-175.7-600000111.8Y26 V27 F32 L178 Y208Y26-T30 WeakPolarHBondContact CA-O 3.28Å; Y26-T30 VanDerWaalsContact CD1-C 3.47Å; V27-T30 PolarHBondContact N-O 3.43Å; V27-T30 PolarHBondContact O-N 3.3Å; T30-F32 PolarHBondContact O-N 3.41Å; T30-L178 HydrophobicContact CG2-CD2 4.13Å; T30-Y208 PolarHBondContact OG1-OH 3.04Å
31Q97.3Very high97.5Very high50 Ų5032.5 Ų32.523%0.23419%0.189CC..EExtended strand (participates in β ladder)trans-68.3130.3173.8-166179.43.800110.5V24 G25 Y26 V33 R47V24-Q31 VanDerWaalsContact CG1-NE2 3.26Å; G25-Q31 WeakPolarHBondContact O-CA 3.44Å; Y26-Q31 HydrophobicContact CD1-CB 3.97Å; Y26-Q31 VanDerWaalsContact CD1-N 3.29Å; Y26-Q31 HydrophobicContact CD2-CG 4.41Å; Y26-Q31 HydrophobicContact CE1-CB 3.48Å; Y26-Q31 VanDerWaalsContact CE1-CB 3.48Å; Y26-Q31 HydrophobicContact CE1-CG 4.17Å; Y26-Q31 HydrophobicContact CE2-CB 4.16Å; Y26-Q31 HydrophobicContact CE2-CG 3.91Å; Y26-Q31 HydrophobicContact CG-CB 4.49Å; Q31-V33 PolarHBondContact NE2-O 2.94Å; Q31-R47 HydrophobicContact CB-CB 4.49Å; Q31-R47 HydrophobicContact CG-CB 4.11Å; Q31-R47 HydrophobicContact CG-CG 4.36Å; Q31-R47 CarbonylContact O-C 3.55Å
32F98.2Very high97.4Very high0 Ų036.7 Ų36.70%021%0.209CC..EExtended strand (participates in β ladder)trans-120.5-22.2179.974.4-83.2000114.4M4 Y6 G25 V27 T30 R47 A48 W50 I51 Y170M4-F32 HydrophobicContact CG-CE1 4.38Å; M4-F32 HydrophobicContact CG-CZ 4.5Å; M4-F32 HydrophobicContact SD-CZ 4.26Å; Y6-F32 AromaticContact CE1-CZ 3.9Å; Y6-F32 HydrophobicContact CE1-CZ 3.9Å; Y6-F32 AromaticContact CZ-CZ 3.7Å; Y6-F32 WeakPolarHBondContact OH-CZ 3.1Å; G25-F32 WeakPolarHBondContact O-CD1 3.34Å; G25-F32 PolarHBondContact O-N 2.92Å; V27-F32 HydrophobicContact CG2-CD1 3.97Å; V27-F32 HydrophobicContact CG2-CE1 3.99Å; T30-F32 PolarHBondContact O-N 3.41Å; F32-R47 PolarHBondContact O-N 2.71Å; F32-A48 HydrophobicContact CB-CB 4.17Å; F32-W50 HydrophobicContact CB-CH2 3.11Å; F32-W50 HydrophobicContact CB-CZ2 3.36Å; F32-W50 HydrophobicContact CB-CZ3 3.93Å; F32-W50 HydrophobicContact CD1-CH2 4.08Å; F32-W50 AromaticContact CD2-CH2 3.87Å; F32-W50 HydrophobicContact CD2-CH2 3.87Å; F32-W50 HydrophobicContact CD2-CZ3 4.13Å; F32-W50 AromaticContact CG-CH2 3.45Å; F32-W50 HydrophobicContact CG-CH2 3.45Å; F32-W50 VanDerWaalsContact CG-CH2 3.45Å; F32-W50 HydrophobicContact CG-CZ2 4.15Å; F32-W50 HydrophobicContact CG-CZ3 4.17Å; F32-I51 HydrophobicContact CD2-CB 4.47Å; F32-I51 HydrophobicContact CD2-CD1 3.94Å; F32-I51 HydrophobicContact CD2-CG1 4.01Å; F32-I51 HydrophobicContact CE2-CD1 4.33Å; F32-I51 VanDerWaalsContact O-CG2 3.25Å; F32-I51 WeakPolarHBondContact O-CG2 3.36Å; F32-Y170 HydrophobicContact CD2-CE2 4.43Å; F32-Y170 HydrophobicContact CE2-CD2 4.21Å; F32-Y170 AromaticContact CE2-CE2 3.62Å; F32-Y170 HydrophobicContact CE2-CE2 3.62Å; F32-Y170 AromaticContact CE2-CZ 3.99Å; F32-Y170 HydrophobicContact CZ-CD2 4.27Å; F32-Y170 AromaticContact CZ-CE2 3.78Å; F32-Y170 HydrophobicContact CZ-CE2 3.78Å
33V98.5Very high97.4Very high1 Ų142 Ų421%0.00623%0.226CC..EExtended strand (participates in β ladder)trans-140.5152.9176.5-72.60000112.8Y6 V24 G25 Q31 M44 E45 I51 W59Y6-V33 HydrophobicContact CE1-CG2 3.96Å; V24-V33 WeakPolarHBondContact CA-O 3.4Å; G25-V33 PolarHBondContact N-O 3.37Å; G25-V33 VanDerWaalsContact N-O 3.07Å; G25-V33 PolarHBondContact O-N 3.04Å; Q31-V33 PolarHBondContact NE2-O 2.94Å; V33-M44 HydrophobicContact CB-CG 4.14Å; V33-M44 HydrophobicContact CB-SD 3.69Å; V33-M44 HydrophobicContact CG1-CG 4.18Å; V33-M44 HydrophobicContact CG1-SD 4.37Å; V33-M44 HydrophobicContact CG2-SD 4.15Å; V33-E45 WeakPolarHBondContact CA-O 3.36Å; V33-I51 HydrophobicContact CG1-CG1 4.36Å; V33-W59 HydrophobicContact CG1-CH2 4.14Å; V33-W59 HydrophobicContact CG1-CZ3 3.92Å
34R98.5Very high97.3Very high65 Ų6542.5 Ų42.525%0.24523%0.229CC..EExtended strand (participates in β ladder)trans-144.8143.5172.7-179173.7172.794.16.3111.4A23 V24 D36 M44 E45 R47A23-R34 CarbonylContact O-C 3.58Å; A23-R34 VanDerWaalsContact O-CA 3.31Å; A23-R34 WeakPolarHBondContact O-CA 3.31Å; V24-R34 HydrophobicContact CG1-CB 4.49Å; V24-R34 HydrophobicContact CG1-CG 4.19Å; R34-D36 IonicContact NH2-OD2 2.85Å; R34-D36 PolarHBondContact NH2-OD2 3.39Å; R34-M44 VanDerWaalsContact C-SD 3.55Å; R34-E45 PolarHBondContact N-O 2.9Å; R34-E45 PolarHBondContact O-N 3.42Å; R34-R47 HydrophobicContact CB-CG 3.85Å
35F98.8Very high97.3Very high5 Ų544.2 Ų44.22%0.02224%0.235CC..EExtended strand (participates in β ladder)trans-130.1143.4165175.9-83.4000109.5F21 I22 A23 Q42 R43 M44 V66 K67F21-F35 AromaticContact CD1-CD1 3.66Å; F21-F35 HydrophobicContact CD1-CD1 3.66Å; F21-F35 AromaticContact CD1-CE1 3.75Å; F21-F35 HydrophobicContact CD1-CE1 3.75Å; F21-F35 AromaticContact CE1-CD1 3.98Å; F21-F35 HydrophobicContact CE1-CD1 3.98Å; F21-F35 HydrophobicContact CE1-CE1 4.35Å; I22-F35 WeakPolarHBondContact CA-O 3.28Å; A23-F35 HydrophobicContact CB-CB 4.27Å; A23-F35 PolarHBondContact N-O 3.38Å; A23-F35 PolarHBondContact O-N 3Å; F35-Q42 VanDerWaalsContact CE2-C 3.48Å; F35-Q42 HydrophobicContact CE2-CB 4.48Å; F35-Q42 WeakPolarHBondContact CE2-O 3.49Å; F35-Q42 HydrophobicContact CZ-CB 4.5Å; F35-R43 WeakPolarHBondContact CD2-O 3.36Å; F35-M44 HydrophobicContact CB-CE 4.35Å; F35-M44 HydrophobicContact CB-SD 3.99Å; F35-V66 HydrophobicContact CB-CG2 4.04Å; F35-V66 HydrophobicContact CD1-CG2 4.15Å; F35-V66 HydrophobicContact CD2-CG2 3.42Å; F35-V66 VanDerWaalsContact CD2-CG2 3.42Å; F35-V66 HydrophobicContact CE2-CG2 3.82Å; F35-V66 HydrophobicContact CG-CB 4.35Å; F35-V66 HydrophobicContact CG-CG2 3.6Å; F35-V66 HydrophobicContact CZ-CG2 4.36Å; F35-K67 HydrophobicContact CE2-CG 4.14Å; F35-K67 HydrophobicContact CZ-CG 4.02Å
36D98.5Very high97.3Very high21 Ų2146.3 Ų46.311%0.11225%0.249CC..EExtended strand (participates in β ladder)trans-138.2122.8174-162.6-32.6000109.1R20 R34 D38 A39R20-D36 IonicContact CZ-OD1 3.76Å; R20-D36 IonicContact CZ-OD2 3.66Å; R20-D36 IonicContact NE-OD1 2.71Å; R20-D36 PolarHBondContact NE-OD1 3.3Å; R20-D36 VanDerWaalsContact NE-OD1 3.14Å; R20-D36 IonicContact NE-OD2 3.52Å; R20-D36 IonicContact NH2-OD1 3.51Å; R20-D36 IonicContact NH2-OD2 2.73Å; R20-D36 PolarHBondContact NH2-OD2 2.9Å; R34-D36 IonicContact NH2-OD2 2.85Å; R34-D36 PolarHBondContact NH2-OD2 3.39Å; D36-D38 PolarHBondContact O-N 2.94Å; D36-D38 PolarHBondContact OD1-N 2.93Å; D36-D38 VanDerWaalsContact OD1-N 3.17Å; D36-A39 HydrophobicContact CB-CB 4.12Å; D36-A39 WeakPolarHBondContact O-CB 3.33Å; D36-A39 PolarHBondContact O-N 2.92Å; D36-A39 VanDerWaalsContact O-N 3.14Å
37S97.9Very high97.2Very high16 Ų1647.9 Ų47.911%0.11225%0.254CS..THydrogen-bonded Turntrans-64.2-24.1-179.263.80000113.1F21 Q42F21-S37 PolarHBondContact N-OG 3.02Å; F21-S37 PolarHBondContact O-N 3.43Å; F21-S37 PolarHBondContact O-OG 3.49Å; S37-Q42 PolarHBondContact O-NE2 3.02Å
38D97Very high97.1Very high78 Ų7848.1 Ų48.142%0.41726%0.256SS..THydrogen-bonded Turntrans-87.5-8.7179.8-69.70.4000112.2R13 R20 D36R13-D38 IonicContact CZ-OD1 3.53Å; R13-D38 IonicContact CZ-OD2 3.65Å; R13-D38 IonicContact NH1-OD1 3.01Å; R13-D38 PolarHBondContact NH1-OD1 3.29Å; R13-D38 IonicContact NH1-OD2 3.08Å; R13-D38 PolarHBondContact NH1-OD2 3.43Å; R13-D38 IonicContact NH2-OD1 2.84Å; R13-D38 PolarHBondContact NH2-OD1 3.48Å; R13-D38 IonicContact NH2-OD2 3.73Å; R20-D38 VanDerWaalsContact CD-OD2 3.29Å; R20-D38 WeakPolarHBondContact CD-OD2 3.43Å; R20-D38 IonicContact NE-OD2 2.78Å; D36-D38 PolarHBondContact O-N 2.94Å; D36-D38 PolarHBondContact OD1-N 2.93Å; D36-D38 VanDerWaalsContact OD1-N 3.17Å
39A96.9Very high97.1Very high32 Ų3251.6 Ų51.626%0.26428%0.28SS..SBendtrans-71142.4175.700000111.2D36 S41 Q42D36-A39 HydrophobicContact CB-CB 4.12Å; D36-A39 WeakPolarHBondContact O-CB 3.33Å; D36-A39 PolarHBondContact O-N 2.92Å; D36-A39 VanDerWaalsContact O-N 3.14Å; A39-S41 VanDerWaalsContact C-N 3.25Å; A39-S41 PolarHBondContact O-N 2.87Å; A39-Q42 WeakPolarHBondContact O-CG 3.43Å; A39-Q42 PolarHBondContact O-N 3.45Å; A39-Q42 VanDerWaalsContact O-N 3.1Å
40A96.1Very high97.2Very high114 Ų11449.2 Ų49.294%0.94227%0.266SS*.THydrogen-bonded Turntrans-60.7-32.7-179.400000113.6
41S93.6Very high97.3Very high49 Ų4948.2 Ų48.234%0.34326%0.26SS..THydrogen-bonded Turntrans-70.2-33.3178.262.70000112.2A39 R43 E45A39-S41 VanDerWaalsContact C-N 3.25Å; A39-S41 PolarHBondContact O-N 2.87Å; S41-R43 WeakPolarHBondContact O-CG 3.07Å; S41-R43 PolarHBondContact O-N 2.91Å; S41-R43 VanDerWaalsContact O-N 3.15Å; S41-E45 PolarHBondContact OG-OE1 3.48Å
42Q95.6Very high97.3Very high88 Ų8851.8 Ų51.841%0.41128%0.277SS..  trans37.549.5-167-59.9-172-25.800111.9F35 S37 A39 K67F35-Q42 VanDerWaalsContact CE2-C 3.48Å; F35-Q42 HydrophobicContact CE2-CB 4.48Å; F35-Q42 WeakPolarHBondContact CE2-O 3.49Å; F35-Q42 HydrophobicContact CZ-CB 4.5Å; S37-Q42 PolarHBondContact O-NE2 3.02Å; A39-Q42 WeakPolarHBondContact O-CG 3.43Å; A39-Q42 PolarHBondContact O-N 3.45Å; A39-Q42 VanDerWaalsContact O-N 3.1Å; Q42-K67 WeakPolarHBondContact O-CE 3.23Å; Q42-K67 PolarHBondContact O-NZ 3.06Å
43R97.8Very high97.1Very high152 Ų15257.7 Ų57.757%0.57430%0.304SS*.SBendtrans-124.2156.3179.1-82.4-179.7171.5132.3-1.1110.3F35 S41 E45 T63F35-R43 WeakPolarHBondContact CD2-O 3.36Å; S41-R43 WeakPolarHBondContact O-CG 3.07Å; S41-R43 PolarHBondContact O-N 2.91Å; S41-R43 VanDerWaalsContact O-N 3.15Å; R43-E45 PolarHBondContact O-N 3.4Å; R43-T63 HydrophobicContact CG-CG2 4.14Å
44M98.3Very high97.1Very high11 Ų1158.1 Ų58.15%0.05431%0.306CS..  trans-68.5127166.2-173.665.583.600108V33 R34 F35 W59 N62 T63 V66V33-M44 HydrophobicContact CB-CG 4.14Å; V33-M44 HydrophobicContact CB-SD 3.69Å; V33-M44 HydrophobicContact CG1-CG 4.18Å; V33-M44 HydrophobicContact CG1-SD 4.37Å; V33-M44 HydrophobicContact CG2-SD 4.15Å; R34-M44 VanDerWaalsContact C-SD 3.55Å; F35-M44 HydrophobicContact CB-CE 4.35Å; F35-M44 HydrophobicContact CB-SD 3.99Å; M44-W59 HydrophobicContact CB-CE3 4.27Å; M44-W59 HydrophobicContact CG-CE3 4.13Å; M44-W59 HydrophobicContact CG-CZ3 3.99Å; M44-N62 HydrophobicContact CB-CB 4.3Å; M44-N62 HydrophobicContact CE-CB 4.4Å; M44-N62 HydrophobicContact CG-CB 4.24Å; M44-T63 PolarHBondContact N-OG1 3.09Å; M44-V66 HydrophobicContact CE-CB 4.39Å; M44-V66 HydrophobicContact CE-CG1 3.37Å; M44-V66 HydrophobicContact CE-CG2 4.19Å
45E98.1Very high97Very high58 Ų5856.8 Ų56.827%0.27131%0.313SS..EExtended strand (participates in β ladder)trans-117.2143-175.4-63.4176.7173.900110.8V33 R34 S41 R43 R47V33-E45 WeakPolarHBondContact CA-O 3.36Å; R34-E45 PolarHBondContact N-O 2.9Å; R34-E45 PolarHBondContact O-N 3.42Å; S41-E45 PolarHBondContact OG-OE1 3.48Å; R43-E45 PolarHBondContact O-N 3.4Å; E45-R47 IonicContact OE2-CZ 2.98Å; E45-R47 IonicContact OE2-NH1 4Å; E45-R47 PolarHBondContact OE2-NH1 3.39Å; E45-R47 VanDerWaalsContact OE2-NH1 3.12Å; E45-R47 IonicContact OE2-NH2 2.68Å; E45-R47 PolarHBondContact OE2-NH2 2.84Å
46P98.1Very high97Very high44 Ų4461.5 Ų61.529%0.28634%0.344SS..EExtended strand (participates in β ladder)trans-67.5148.1174.628.8-34.5000111.2I51 E52 W59P46-I51 HydrophobicContact CB-CG2 3.65Å; P46-E52 HydrophobicContact CB-CG 3.78Å; P46-E52 HydrophobicContact CG-CG 4.03Å; P46-W59 HydrophobicContact CB-CH2 3.64Å; P46-W59 HydrophobicContact CB-CZ2 4.06Å; P46-W59 HydrophobicContact CB-CZ3 4.47Å; P46-W59 HydrophobicContact CG-CH2 4.27Å; P46-W59 HydrophobicContact CG-CZ2 4.49Å
47R97.3Very high96.9Very high101 Ų10168.6 Ų68.638%0.38138%0.376SS..  trans-1301.1172.9-65.1-63.7-178.8-94.52.4113.4Q31 F32 R34 E45Q31-R47 HydrophobicContact CB-CB 4.49Å; Q31-R47 HydrophobicContact CG-CB 4.11Å; Q31-R47 HydrophobicContact CG-CG 4.36Å; Q31-R47 CarbonylContact O-C 3.55Å; F32-R47 PolarHBondContact O-N 2.71Å; R34-R47 HydrophobicContact CB-CG 3.85Å; E45-R47 IonicContact OE2-CZ 2.98Å; E45-R47 IonicContact OE2-NH1 4Å; E45-R47 PolarHBondContact OE2-NH1 3.39Å; E45-R47 VanDerWaalsContact OE2-NH1 3.12Å; E45-R47 IonicContact OE2-NH2 2.68Å; E45-R47 PolarHBondContact OE2-NH2 2.84Å
48A96.1Very high96.9Very high6 Ų668.3 Ų68.35%0.0537%0.373CS..SBendtrans-138.9144.2173.200000110.7F32 W50 I51F32-A48 HydrophobicContact CB-CB 4.17Å; A48-W50 VanDerWaalsContact C-N 3.29Å; A48-W50 HydrophobicContact CB-CD2 4.15Å; A48-W50 HydrophobicContact CB-CG 4.36Å; A48-W50 HydrophobicContact CB-CZ2 3.96Å; A48-W50 PolarHBondContact O-N 2.71Å; A48-I51 WeakPolarHBondContact O-CG2 3.36Å; A48-I51 PolarHBondContact O-N 2.95Å
49P96.3Very high97Very high103 Ų10366.5 Ų66.567%0.66936%0.36SS*.G310 helixtrans-58.9-38.3-177-26.434.8000113.7I51 E52P49-I51 PolarHBondContact O-N 3.22Å; P49-E52 WeakPolarHBondContact O-CB 3.19Å; P49-E52 PolarHBondContact O-N 3.18Å; P49-E52 VanDerWaalsContact O-N 3.09Å
50W96.4Very high97Very high18 Ų1869 Ų697%0.06837%0.369CS..G310 helixtrans-69-13.6-176.453.7-105.4000114.4V27 F32 A48 Q53 Y170 G174 L178V27-W50 HydrophobicContact CB-CH2 4.43Å; V27-W50 HydrophobicContact CG2-CH2 3.95Å; F32-W50 HydrophobicContact CB-CH2 3.11Å; F32-W50 HydrophobicContact CB-CZ2 3.36Å; F32-W50 HydrophobicContact CB-CZ3 3.93Å; F32-W50 HydrophobicContact CD1-CH2 4.08Å; F32-W50 AromaticContact CD2-CH2 3.87Å; F32-W50 HydrophobicContact CD2-CH2 3.87Å; F32-W50 HydrophobicContact CD2-CZ3 4.13Å; F32-W50 AromaticContact CG-CH2 3.45Å; F32-W50 HydrophobicContact CG-CH2 3.45Å; F32-W50 VanDerWaalsContact CG-CH2 3.45Å; F32-W50 HydrophobicContact CG-CZ2 4.15Å; F32-W50 HydrophobicContact CG-CZ3 4.17Å; A48-W50 VanDerWaalsContact C-N 3.29Å; A48-W50 HydrophobicContact CB-CD2 4.15Å; A48-W50 HydrophobicContact CB-CG 4.36Å; A48-W50 HydrophobicContact CB-CZ2 3.96Å; A48-W50 PolarHBondContact O-N 2.71Å; W50-Q53 WeakPolarHBondContact O-CG 3.1Å; W50-Y170 HydrophobicContact CH2-CG 4.3Å; W50-Y170 AromaticContact CZ3-CD1 3.88Å; W50-Y170 HydrophobicContact CZ3-CD1 3.88Å; W50-Y170 HydrophobicContact CZ3-CD2 4.41Å; W50-Y170 AromaticContact CZ3-CG 3.74Å; W50-Y170 HydrophobicContact CZ3-CG 3.74Å; W50-G174 VanDerWaalsContact CG-CA 3.49Å; W50-L178 HydrophobicContact CD2-CD1 4.42Å; W50-L178 HydrophobicContact CH2-CD1 4.25Å; W50-L178 HydrophobicContact CZ2-CD1 3.82Å; W50-L178 HydrophobicContact CZ2-CD2 4Å; W50-L178 HydrophobicContact CZ2-CG 4.28Å
51I97.9Very high97.1Very high0 Ų068.2 Ų68.20%034%0.342CS..G310 helixtrans-89.3-19.7173.7-16370.7000112F32 V33 P46 A48 P49 Q53 E54 Y58 W59 Y170F32-I51 HydrophobicContact CD2-CB 4.47Å; F32-I51 HydrophobicContact CD2-CD1 3.94Å; F32-I51 HydrophobicContact CD2-CG1 4.01Å; F32-I51 HydrophobicContact CE2-CD1 4.33Å; F32-I51 VanDerWaalsContact O-CG2 3.25Å; F32-I51 WeakPolarHBondContact O-CG2 3.36Å; V33-I51 HydrophobicContact CG1-CG1 4.36Å; P46-I51 HydrophobicContact CB-CG2 3.65Å; A48-I51 WeakPolarHBondContact O-CG2 3.36Å; A48-I51 PolarHBondContact O-N 2.95Å; P49-I51 PolarHBondContact O-N 3.22Å; I51-Q53 PolarHBondContact O-N 2.94Å; I51-Q53 VanDerWaalsContact O-N 3.17Å; I51-E54 HydrophobicContact CD1-CG 3.7Å; I51-E54 HydrophobicContact CG1-CG 4.25Å; I51-E54 WeakPolarHBondContact O-CB 3.47Å; I51-E54 WeakPolarHBondContact O-CG 3.49Å; I51-E54 PolarHBondContact O-N 3.17Å; I51-Y58 HydrophobicContact CD1-CE1 4.23Å; I51-Y58 HydrophobicContact CG1-CE1 4.23Å; I51-W59 HydrophobicContact CB-CH2 4.49Å; I51-W59 HydrophobicContact CG1-CH2 3.81Å; I51-W59 HydrophobicContact CG1-CZ2 4.09Å; I51-W59 HydrophobicContact CG2-CH2 4Å; I51-W59 HydrophobicContact CG2-CZ2 4.42Å; I51-W59 WeakPolarHBondContact O-CZ2 3.44Å; I51-Y170 HydrophobicContact CD1-CD1 3.8Å; I51-Y170 HydrophobicContact CD1-CE1 3.32Å
52E96.8Very high97.3Very high126 Ų12666.9 Ų66.959%0.58933%0.331SS*.THydrogen-bonded Turntrans-64.3-23.8-175.9-64.4-178-174.700113.2P46 P49 E54P46-E52 HydrophobicContact CB-CG 3.78Å; P46-E52 HydrophobicContact CG-CG 4.03Å; P49-E52 WeakPolarHBondContact O-CB 3.19Å; P49-E52 PolarHBondContact O-N 3.18Å; P49-E52 VanDerWaalsContact O-N 3.09Å; E52-E54 PolarHBondContact O-N 3.04Å
53Q95.6Very high97.5Very high123 Ų12363.3 Ų63.358%0.57532%0.315SS*.THydrogen-bonded Turntrans-71.2-11.3175.567.1-1807.900114.1W50 I51 N173W50-Q53 WeakPolarHBondContact O-CG 3.1Å; I51-Q53 PolarHBondContact O-N 2.94Å; I51-Q53 VanDerWaalsContact O-N 3.17Å; Q53-N173 PolarHBondContact NE2-ND2 3.38Å; Q53-N173 PolarHBondContact NE2-OD1 3.22Å; Q53-N173 VanDerWaalsContact NE2-OD1 3.11Å
54E97.4Very high97.5Very high11 Ų1164.1 Ų64.15%0.05132%0.318CS..SBendtrans-66.2137174.8-66.9-62.9165.100111I51 E52 Y58 W59 R169 N173I51-E54 HydrophobicContact CD1-CG 3.7Å; I51-E54 HydrophobicContact CG1-CG 4.25Å; I51-E54 WeakPolarHBondContact O-CB 3.47Å; I51-E54 WeakPolarHBondContact O-CG 3.49Å; I51-E54 PolarHBondContact O-N 3.17Å; E52-E54 PolarHBondContact O-N 3.04Å; E54-Y58 HydrophobicContact CB-CD1 3.62Å; E54-Y58 HydrophobicContact CB-CD2 4.43Å; E54-Y58 HydrophobicContact CB-CE1 4.27Å; E54-Y58 HydrophobicContact CB-CG 3.72Å; E54-Y58 HydrophobicContact CG-CD1 4.09Å; E54-Y58 HydrophobicContact CG-CD2 4.35Å; E54-Y58 HydrophobicContact CG-CE1 4.34Å; E54-Y58 HydrophobicContact CG-CG 4.11Å; E54-W59 PolarHBondContact O-NE1 3.32Å; E54-R169 IonicContact OE1-CZ 2.81Å; E54-R169 IonicContact OE1-NE 4Å; E54-R169 PolarHBondContact OE1-NE 2.91Å; E54-R169 IonicContact OE1-NH2 3.39Å; E54-R169 PolarHBondContact OE1-NH2 2.89Å; E54-R169 IonicContact OE2-CZ 3.61Å; E54-R169 IonicContact OE2-NE 3.41Å; E54-R169 PolarHBondContact OE2-NE 2.89Å; E54-R169 IonicContact OE2-NH2 3.05Å; E54-R169 PolarHBondContact OE2-NH2 2.79Å; E54-N173 PolarHBondContact OE1-ND2 3.44Å
55G97Very high97.4Very high37 Ų3767.1 Ų67.138%0.38133%0.334SS..  trans-71.6168-174.700000114.3E57 Y58G55-E57 PolarHBondContact O-N 3.37Å; G55-E57 VanDerWaalsContact O-N 3.13Å; G55-Y58 VanDerWaalsContact O-CB 3.3Å; G55-Y58 WeakPolarHBondContact O-CB 3.45Å; G55-Y58 PolarHBondContact O-N 2.95Å
56P97.3Very high97.4Very high103 Ų10364.4 Ų64.467%0.66932%0.322SS*.Hα-helixtrans-52.5-37.3-179-28.235000114.7Y58 W59 D60P56-Y58 VanDerWaalsContact C-N 3.26Å; P56-Y58 PolarHBondContact O-N 3.01Å; P56-W59 PolarHBondContact O-N 2.77Å; P56-W59 VanDerWaalsContact O-N 3.13Å; P56-D60 WeakPolarHBondContact O-CB 3.33Å; P56-D60 PolarHBondContact O-N 3.27Å
57E97.8Very high97.4Very high170 Ų17066.2 Ų66.279%0.79433%0.325SS*.Hα-helixtrans-59.8-35.4178.3-64.4-175.3176.100112.8G55 R61G55-E57 PolarHBondContact O-N 3.37Å; G55-E57 VanDerWaalsContact O-N 3.13Å; E57-R61 WeakPolarHBondContact O-CB 3.27Å; E57-R61 PolarHBondContact O-N 2.97Å
58Y97.8Very high97.4Very high10 Ų1064 Ų644%0.03933%0.329CS..Hα-helixtrans-63.5-49.9175.1173-91.9000110.4I51 E54 G55 P56 R61 N62 W166 Y170I51-Y58 HydrophobicContact CD1-CE1 4.23Å; I51-Y58 HydrophobicContact CG1-CE1 4.23Å; E54-Y58 HydrophobicContact CB-CD1 3.62Å; E54-Y58 HydrophobicContact CB-CD2 4.43Å; E54-Y58 HydrophobicContact CB-CE1 4.27Å; E54-Y58 HydrophobicContact CB-CG 3.72Å; E54-Y58 HydrophobicContact CG-CD1 4.09Å; E54-Y58 HydrophobicContact CG-CD2 4.35Å; E54-Y58 HydrophobicContact CG-CE1 4.34Å; E54-Y58 HydrophobicContact CG-CG 4.11Å; G55-Y58 VanDerWaalsContact O-CB 3.3Å; G55-Y58 WeakPolarHBondContact O-CB 3.45Å; G55-Y58 PolarHBondContact O-N 2.95Å; P56-Y58 VanDerWaalsContact C-N 3.26Å; P56-Y58 PolarHBondContact O-N 3.01Å; Y58-R61 PolarHBondContact O-N 2.61Å; Y58-N62 VanDerWaalsContact CD2-ND2 3.26Å; Y58-N62 WeakPolarHBondContact CD2-ND2 3.21Å; Y58-N62 WeakPolarHBondContact CE1-ND2 3.32Å; Y58-N62 WeakPolarHBondContact CE2-ND2 3.33Å; Y58-N62 WeakPolarHBondContact O-CB 3.4Å; Y58-N62 PolarHBondContact O-N 2.78Å; Y58-N62 PolarHBondContact O-ND2 2.98Å; Y58-W166 AromaticContact CD2-CH2 3.68Å; Y58-W166 HydrophobicContact CD2-CH2 3.68Å; Y58-W166 HydrophobicContact CD2-CZ2 4.38Å; Y58-W166 AromaticContact CD2-CZ3 3.83Å; Y58-W166 HydrophobicContact CD2-CZ3 3.83Å; Y58-W166 HydrophobicContact CE2-CE3 4.23Å; Y58-W166 HydrophobicContact CE2-CH2 4.02Å; Y58-W166 AromaticContact CE2-CZ3 3.8Å; Y58-W166 HydrophobicContact CE2-CZ3 3.8Å; Y58-Y170 WeakPolarHBondContact CE2-OH 3.44Å; Y58-Y170 VanDerWaalsContact CZ-OH 3.26Å; Y58-Y170 PolarHBondContact OH-OH 3.03Å
59W98.3Very high97.5Very high40 Ų4066.2 Ų66.215%0.15234%0.338CS..Hα-helixtrans-66.2-41.8-177.7-63.7110.9000112.3V33 M44 P46 I51 E54 P56 T63V33-W59 HydrophobicContact CG1-CH2 4.14Å; V33-W59 HydrophobicContact CG1-CZ3 3.92Å; M44-W59 HydrophobicContact CB-CE3 4.27Å; M44-W59 HydrophobicContact CG-CE3 4.13Å; M44-W59 HydrophobicContact CG-CZ3 3.99Å; P46-W59 HydrophobicContact CB-CH2 3.64Å; P46-W59 HydrophobicContact CB-CZ2 4.06Å; P46-W59 HydrophobicContact CB-CZ3 4.47Å; P46-W59 HydrophobicContact CG-CH2 4.27Å; P46-W59 HydrophobicContact CG-CZ2 4.49Å; I51-W59 HydrophobicContact CB-CH2 4.49Å; I51-W59 HydrophobicContact CG1-CH2 3.81Å; I51-W59 HydrophobicContact CG1-CZ2 4.09Å; I51-W59 HydrophobicContact CG2-CH2 4Å; I51-W59 HydrophobicContact CG2-CZ2 4.42Å; I51-W59 WeakPolarHBondContact O-CZ2 3.44Å; E54-W59 PolarHBondContact O-NE1 3.32Å; P56-W59 PolarHBondContact O-N 2.77Å; P56-W59 VanDerWaalsContact O-N 3.13Å; W59-T63 VanDerWaalsContact O-CB 3.22Å; W59-T63 WeakPolarHBondContact O-CB 3.47Å; W59-T63 PolarHBondContact O-N 2.92Å; W59-T63 PolarHBondContact O-OG1 2.89Å
60D98.3Very high97.5Very high86 Ų8662.2 Ų62.246%0.4631%0.312SS..Hα-helixtrans-65.9-44.8177.4-76.7-20.6000111.6P56 T63 R64P56-D60 WeakPolarHBondContact O-CB 3.33Å; P56-D60 PolarHBondContact O-N 3.27Å; D60-T63 PolarHBondContact O-N 2.96Å; D60-R64 WeakPolarHBondContact O-CB 3.35Å; D60-R64 PolarHBondContact O-N 2.73Å
61R97.8Very high97.6Very high97 Ų9766.6 Ų66.637%0.36633%0.334SS..Hα-helixtrans-62.6-48.5177-175.8-173.967.5-162.3-4111.2E57 Y58 R64 N65E57-R61 WeakPolarHBondContact O-CB 3.27Å; E57-R61 PolarHBondContact O-N 2.97Å; Y58-R61 PolarHBondContact O-N 2.61Å; R61-R64 PolarHBondContact O-N 3.05Å; R61-N65 PolarHBondContact O-N 2.89Å; R61-N65 PolarHBondContact O-OD1 3.22Å
62N97.8Very high97.5Very high21 Ų2169.9 Ų69.911%0.11235%0.354CS..Hα-helixtrans-66-40-179.7-77.2-68.2000111.8M44 Y58 R64 N65 V66M44-N62 HydrophobicContact CB-CB 4.3Å; M44-N62 HydrophobicContact CE-CB 4.4Å; M44-N62 HydrophobicContact CG-CB 4.24Å; Y58-N62 VanDerWaalsContact CD2-ND2 3.26Å; Y58-N62 WeakPolarHBondContact CD2-ND2 3.21Å; Y58-N62 WeakPolarHBondContact CE1-ND2 3.32Å; Y58-N62 WeakPolarHBondContact CE2-ND2 3.33Å; Y58-N62 WeakPolarHBondContact O-CB 3.4Å; Y58-N62 PolarHBondContact O-N 2.78Å; Y58-N62 PolarHBondContact O-ND2 2.98Å; N62-R64 VanDerWaalsContact C-N 3.35Å; N62-R64 PolarHBondContact O-N 3.46Å; N62-N65 PolarHBondContact O-N 3.33Å; N62-V66 WeakPolarHBondContact O-CG2 3.23Å; N62-V66 PolarHBondContact O-N 3.43Å
63T98.5Very high97.5Very high13 Ų1364 Ų648%0.0833%0.326CS..Hα-helixtrans-59-45.4173.3-63.30000111.4R43 M44 W59 D60 N65 V66 K67R43-T63 HydrophobicContact CG-CG2 4.14Å; M44-T63 PolarHBondContact N-OG1 3.09Å; W59-T63 VanDerWaalsContact O-CB 3.22Å; W59-T63 WeakPolarHBondContact O-CB 3.47Å; W59-T63 PolarHBondContact O-N 2.92Å; W59-T63 PolarHBondContact O-OG1 2.89Å; D60-T63 PolarHBondContact O-N 2.96Å; T63-N65 PolarHBondContact O-N 3.3Å; T63-V66 WeakPolarHBondContact O-CG2 3.12Å; T63-K67 HydrophobicContact CG2-CD 4.23Å; T63-K67 WeakPolarHBondContact O-CB 2.94Å; T63-K67 WeakPolarHBondContact O-CG 3.4Å; T63-K67 PolarHBondContact O-N 2.96Å
64R98.4Very high97.6Very high168 Ų16863.5 Ų63.563%0.63432%0.319SS*.Hα-helixtrans-61.5-44.8176.8-171.1-174.6-60.41333.6111.4D60 R61 N62 K67 A68D60-R64 WeakPolarHBondContact O-CB 3.35Å; D60-R64 PolarHBondContact O-N 2.73Å; R61-R64 PolarHBondContact O-N 3.05Å; N62-R64 VanDerWaalsContact C-N 3.35Å; N62-R64 PolarHBondContact O-N 3.46Å; R64-K67 PolarHBondContact O-N 2.86Å; R64-A68 WeakPolarHBondContact O-CB 3.24Å; R64-A68 PolarHBondContact O-N 3.16Å
65N97.1Very high97.6Very high74 Ų7465.8 Ų65.840%0.39634%0.34SS..Hα-helixtrans-62.6-45-178.7-69.7-8.8000112.4R61 N62 T63 A68 H69R61-N65 PolarHBondContact O-N 2.89Å; R61-N65 PolarHBondContact O-OD1 3.22Å; N62-N65 PolarHBondContact O-N 3.33Å; T63-N65 PolarHBondContact O-N 3.3Å; N65-A68 PolarHBondContact O-N 3.32Å; N65-H69 PolarHBondContact O-N 3.01Å; N65-H69 PolarHBondContact O-ND1 2.82Å
66V97.7Very high97.6Very high1 Ų166.5 Ų66.51%0.00634%0.335CS..Hα-helixtrans-71.6-32.7178.5-64.10000112.7F21 A23 F35 M44 N62 T63 H69 S70F21-V66 HydrophobicContact CE1-CB 4.12Å; A23-V66 HydrophobicContact CB-CG1 4.22Å; F35-V66 HydrophobicContact CB-CG2 4.04Å; F35-V66 HydrophobicContact CD1-CG2 4.15Å; F35-V66 HydrophobicContact CD2-CG2 3.42Å; F35-V66 VanDerWaalsContact CD2-CG2 3.42Å; F35-V66 HydrophobicContact CE2-CG2 3.82Å; F35-V66 HydrophobicContact CG-CB 4.35Å; F35-V66 HydrophobicContact CG-CG2 3.6Å; F35-V66 HydrophobicContact CZ-CG2 4.36Å; M44-V66 HydrophobicContact CE-CB 4.39Å; M44-V66 HydrophobicContact CE-CG1 3.37Å; M44-V66 HydrophobicContact CE-CG2 4.19Å; N62-V66 WeakPolarHBondContact O-CG2 3.23Å; N62-V66 PolarHBondContact O-N 3.43Å; T63-V66 WeakPolarHBondContact O-CG2 3.12Å; V66-H69 PolarHBondContact O-N 2.81Å; V66-S70 WeakPolarHBondContact O-CB 3.25Å; V66-S70 PolarHBondContact O-N 2.89Å
67K98Very high97.6Very high82 Ų8262 Ų6236%0.35731%0.306SS..Hα-helixtrans-65.2-42.1171.6-75.5-173.7179.8-172.70112F35 Q42 T63 R64 H69 S70 Q71F35-K67 HydrophobicContact CE2-CG 4.14Å; F35-K67 HydrophobicContact CZ-CG 4.02Å; Q42-K67 WeakPolarHBondContact O-CE 3.23Å; Q42-K67 PolarHBondContact O-NZ 3.06Å; T63-K67 HydrophobicContact CG2-CD 4.23Å; T63-K67 WeakPolarHBondContact O-CB 2.94Å; T63-K67 WeakPolarHBondContact O-CG 3.4Å; T63-K67 PolarHBondContact O-N 2.96Å; R64-K67 PolarHBondContact O-N 2.86Å; K67-H69 VanDerWaalsContact C-N 3.35Å; K67-S70 WeakPolarHBondContact O-CB 3.36Å; K67-S70 PolarHBondContact O-N 3.29Å; K67-Q71 WeakPolarHBondContact O-CG 3.33Å; K67-Q71 PolarHBondContact O-N 3.24Å; K67-Q71 VanDerWaalsContact O-N 3.11Å
68A97.9Very high97.4Very high55 Ų5555.7 Ų55.746%0.45529%0.285SS..Hα-helixtrans-63-41.9175.300000111.7R64 N65 Q71 T72R64-A68 WeakPolarHBondContact O-CB 3.24Å; R64-A68 PolarHBondContact O-N 3.16Å; N65-A68 PolarHBondContact O-N 3.32Å; A68-Q71 PolarHBondContact O-N 2.7Å; A68-T72 PolarHBondContact O-N 3.16Å; A68-T72 PolarHBondContact O-OG1 3.01Å
69H96.8Very high97.4Very high52 Ų5257.9 Ų57.924%0.24130%0.3CS..Hα-helixtrans-62-44.6172.9-90.183000112.2Y8 F21 N65 V66 K67 Q71 T72 D73 R96Y8-H69 HydrophobicContact CD2-CB 4.43Å; Y8-H69 HydrophobicContact CE2-CB 4.2Å; Y8-H69 AromaticContact CE2-CD2 3.87Å; Y8-H69 AromaticContact CE2-CG 3.9Å; F21-H69 HydrophobicContact CE2-CB 4.42Å; F21-H69 HydrophobicContact CZ-CB 4.24Å; N65-H69 PolarHBondContact O-N 3.01Å; N65-H69 PolarHBondContact O-ND1 2.82Å; V66-H69 PolarHBondContact O-N 2.81Å; K67-H69 VanDerWaalsContact C-N 3.35Å; H69-Q71 VanDerWaalsContact C-N 3.29Å; H69-Q71 PolarHBondContact O-N 2.82Å; H69-T72 CarbonylContact O-C 3.58Å; H69-T72 WeakPolarHBondContact O-CA 3.26Å; H69-T72 WeakPolarHBondContact O-CB 3.47Å; H69-T72 PolarHBondContact O-N 3.01Å; H69-D73 PolarHBondContact O-N 2.86Å; H69-R96 PolarHBondContact NE2-NH1 3.48Å
70S97.4Very high97.4Very high19 Ų1956.5 Ų56.513%0.13330%0.295CS..Hα-helixtrans-56.8-40176.7174.70000112.9F21 V66 K67 R74F21-S70 WeakPolarHBondContact CB-OG 3.38Å; F21-S70 VanDerWaalsContact CG-CB 3.5Å; V66-S70 WeakPolarHBondContact O-CB 3.25Å; V66-S70 PolarHBondContact O-N 2.89Å; K67-S70 WeakPolarHBondContact O-CB 3.36Å; K67-S70 PolarHBondContact O-N 3.29Å; S70-R74 PolarHBondContact O-N 2.86Å
71Q97.3Very high97.3Very high111 Ų11155.9 Ų55.952%0.51929%0.287SS..Hα-helixtrans-69.5-36.1174.5-63.8-55.6-40.800112.6K67 A68 H69 R74 A75K67-Q71 WeakPolarHBondContact O-CG 3.33Å; K67-Q71 PolarHBondContact O-N 3.24Å; K67-Q71 VanDerWaalsContact O-N 3.11Å; A68-Q71 PolarHBondContact O-N 2.7Å; H69-Q71 VanDerWaalsContact C-N 3.29Å; H69-Q71 PolarHBondContact O-N 2.82Å; Q71-R74 WeakPolarHBondContact O-CB 3.38Å; Q71-R74 PolarHBondContact O-N 2.91Å; Q71-A75 PolarHBondContact O-N 2.88Å
72T97.3Very high97.2Very high69 Ų6953.4 Ų53.442%0.42329%0.291SS..Hα-helixtrans-64.4-46.8175.7-56.30000110.6A68 H69 R74 A75 N76A68-T72 PolarHBondContact O-N 3.16Å; A68-T72 PolarHBondContact O-OG1 3.01Å; H69-T72 CarbonylContact O-C 3.58Å; H69-T72 WeakPolarHBondContact O-CA 3.26Å; H69-T72 WeakPolarHBondContact O-CB 3.47Å; H69-T72 PolarHBondContact O-N 3.01Å; T72-R74 VanDerWaalsContact C-N 3.31Å; T72-R74 PolarHBondContact O-N 3.05Å; T72-A75 PolarHBondContact O-N 3.17Å; T72-A75 VanDerWaalsContact O-N 3.14Å; T72-N76 WeakPolarHBondContact O-CB 3.33Å; T72-N76 VanDerWaalsContact O-CG 3.25Å; T72-N76 PolarHBondContact O-N 2.79Å; T72-N76 PolarHBondContact O-ND2 3.02Å
73D96.9Very high97.2Very high2 Ų255 Ų551%0.01130%0.296CS..Hα-helixtrans-63.1-37.1177.4-80.211.4000112.2S10 H69 A75 N76 L77S10-D73 WeakPolarHBondContact OG-CB 3.37Å; S10-D73 PolarHBondContact OG-OD2 3.32Å; H69-D73 PolarHBondContact O-N 2.86Å; D73-A75 VanDerWaalsContact C-N 3.34Å; D73-A75 PolarHBondContact O-N 2.76Å; D73-N76 PolarHBondContact O-N 2.91Å; D73-L77 WeakPolarHBondContact O-CG 3.03Å; D73-L77 PolarHBondContact O-N 3Å
74R96.5Very high97.1Very high112 Ų11257.5 Ų57.542%0.42331%0.305SS..Hα-helixtrans-57.2-46.9172.4174.8-170.3169.1158.717.2111.6E18 P19 S70 Q71 T72E18-R74 IonicContact OE1-CZ 3.76Å; E18-R74 IonicContact OE1-NE 3.01Å; E18-R74 IonicContact OE1-NH1 2.7Å; E18-R74 PolarHBondContact OE1-NH1 3.32Å; E18-R74 IonicContact OE1-NH2 3.14Å; E18-R74 PolarHBondContact OE1-NH2 3.38Å; E18-R74 WeakPolarHBondContact OE2-CD 3.34Å; E18-R74 IonicContact OE2-CZ 2.71Å; E18-R74 IonicContact OE2-NE 3.67Å; E18-R74 PolarHBondContact OE2-NE 3.49Å; E18-R74 IonicContact OE2-NH1 3.02Å; E18-R74 PolarHBondContact OE2-NH1 2.89Å; E18-R74 IonicContact OE2-NH2 3.72Å; E18-R74 PolarHBondContact OE2-NH2 2.9Å; E18-R74 VanDerWaalsContact OE2-NH2 3.08Å; P19-R74 HydrophobicContact CG-CB 4.35Å; P19-R74 HydrophobicContact CG-CG 4.17Å; S70-R74 PolarHBondContact O-N 2.86Å; Q71-R74 WeakPolarHBondContact O-CB 3.38Å; Q71-R74 PolarHBondContact O-N 2.91Å; T72-R74 VanDerWaalsContact C-N 3.31Å; T72-R74 PolarHBondContact O-N 3.05Å
75A96.9Very high97Very high59 Ų5956.7 Ų56.749%0.48831%0.313SS..Hα-helixtrans-67.6-38.717700000111.7Q71 T72 D73 L77 G78 T79Q71-A75 PolarHBondContact O-N 2.88Å; T72-A75 PolarHBondContact O-N 3.17Å; T72-A75 VanDerWaalsContact O-N 3.14Å; D73-A75 VanDerWaalsContact C-N 3.34Å; D73-A75 PolarHBondContact O-N 2.76Å; A75-L77 PolarHBondContact O-N 3.23Å; A75-G78 PolarHBondContact O-N 2.88Å; A75-T79 PolarHBondContact O-N 2.03Å; A75-T79 PolarHBondContact O-OG1 2.99Å; A75-T79 VanDerWaalsContact O-OG1 3.06Å
76N97.5Very high96.9Very high52 Ų5256 Ų5628%0.27831%0.307SS..Hα-helixtrans-66-36178.4-70.7-17.6000112.2T72 D73 G78 T79 L80 I94T72-N76 WeakPolarHBondContact O-CB 3.33Å; T72-N76 VanDerWaalsContact O-CG 3.25Å; T72-N76 PolarHBondContact O-N 2.79Å; T72-N76 PolarHBondContact O-ND2 3.02Å; D73-N76 PolarHBondContact O-N 2.91Å; N76-G78 VanDerWaalsContact C-N 3.29Å; N76-G78 PolarHBondContact O-N 2.93Å; N76-T79 PolarHBondContact O-N 2.8Å; N76-T79 VanDerWaalsContact O-N 3.12Å; N76-L80 WeakPolarHBondContact O-CB 3.39Å; N76-L80 WeakPolarHBondContact O-CG 3.39Å; N76-L80 PolarHBondContact O-N 2.95Å; N76-I94 HydrophobicContact CB-CD1 3.63Å
77L97.1Very high96.6Very high10 Ų1058.4 Ų58.45%0.05233%0.333CS..Hα-helixtrans-57.8-42.7174.8-80.9164.4000111.4P19 D73 A75 R81 H92 I94 Y117P19-L77 HydrophobicContact CB-CD1 3.62Å; P19-L77 HydrophobicContact CG-CD1 3.64Å; D73-L77 WeakPolarHBondContact O-CG 3.03Å; D73-L77 PolarHBondContact O-N 3Å; A75-L77 PolarHBondContact O-N 3.23Å; L77-R81 VanDerWaalsContact O-CB 3.32Å; L77-R81 WeakPolarHBondContact O-CB 3.27Å; L77-R81 PolarHBondContact O-N 3.39Å; L77-R81 VanDerWaalsContact O-N 3.14Å; L77-H92 HydrophobicContact CD2-CB 4.05Å; L77-I94 HydrophobicContact CB-CD1 4.42Å; L77-I94 HydrophobicContact CD2-CD1 3.96Å; L77-I94 HydrophobicContact CD2-CG1 3.77Å; L77-I94 HydrophobicContact CG-CD1 3.73Å; L77-I94 HydrophobicContact CG-CG1 4.09Å; L77-Y117 HydrophobicContact CD2-CE2 4.34Å
78G95.1Very high96.1Very high36 Ų3661 Ų6137%0.37135%0.346SS..Hα-helixtrans-68.2-39.2174.500000112.9A75 N76 G82A75-G78 PolarHBondContact O-N 2.88Å; N76-G78 VanDerWaalsContact C-N 3.29Å; N76-G78 PolarHBondContact O-N 2.93Å; G78-G82 PolarHBondContact O-N 3.3Å; G78-G82 VanDerWaalsContact O-N 3.17Å
79T97Very high95.6Very high56 Ų5665.9 Ų65.934%0.34436%0.364SS..Hα-helixtrans-64.7-48.6178.7-59.60000111.9A75 N76 G82 Y83A75-T79 PolarHBondContact O-N 2.03Å; A75-T79 PolarHBondContact O-OG1 2.99Å; A75-T79 VanDerWaalsContact O-OG1 3.06Å; N76-T79 PolarHBondContact O-N 2.8Å; N76-T79 VanDerWaalsContact O-N 3.12Å; T79-G82 PolarHBondContact O-N 2.86Å; T79-G82 VanDerWaalsContact O-N 3.16Å; T79-Y83 HydrophobicContact CG2-CD1 4.38Å; T79-Y83 HydrophobicContact CG2-CD2 4.44Å; T79-Y83 HydrophobicContact CG2-CE1 3.8Å; T79-Y83 HydrophobicContact CG2-CE2 3.86Å; T79-Y83 PolarHBondContact O-N 2.84Å
80L97.7Very high95.3Very high11 Ų1164.8 Ų64.86%0.05837%0.367CS..Hα-helixtrans-64.1-43.4179.7-68.4173.8000111.1N76 G82 Y83 Y84 I94 Y117 Y122N76-L80 WeakPolarHBondContact O-CB 3.39Å; N76-L80 WeakPolarHBondContact O-CG 3.39Å; N76-L80 PolarHBondContact O-N 2.95Å; L80-G82 PolarHBondContact O-N 2.95Å; L80-Y83 HydrophobicContact CD2-CD2 4.24Å; L80-Y83 PolarHBondContact O-N 3.39Å; L80-Y84 HydrophobicContact CD2-CE2 4.34Å; L80-Y84 WeakPolarHBondContact O-CD2 3.41Å; L80-Y84 PolarHBondContact O-N 3.15Å; L80-I94 HydrophobicContact CD1-CD1 3.59Å; L80-I94 HydrophobicContact CD1-CG1 3.69Å; L80-Y117 HydrophobicContact CB-CD1 4.39Å; L80-Y117 HydrophobicContact CB-CD2 4.2Å; L80-Y117 HydrophobicContact CB-CE1 4.01Å; L80-Y117 HydrophobicContact CB-CE2 3.83Å; L80-Y117 HydrophobicContact CB-CG 4.46Å; L80-Y117 HydrophobicContact CD1-CD2 3.46Å; L80-Y117 VanDerWaalsContact CD1-CD2 3.46Å; L80-Y117 HydrophobicContact CD1-CE2 3.82Å; L80-Y117 HydrophobicContact CD1-CG 3.86Å; L80-Y117 HydrophobicContact CG-CD2 4.44Å; L80-Y117 HydrophobicContact CG-CE2 4.49Å; L80-Y122 HydrophobicContact CD2-CD2 4.41Å; L80-Y122 HydrophobicContact CD2-CE1 3.79Å; L80-Y122 HydrophobicContact CD2-CE2 3.66Å; L80-Y122 WeakPolarHBondContact CD2-OH 3.37Å
81R96.2Very high95.3Very high74 Ų7467.3 Ų67.328%0.27939%0.385SS..Hα-helixtrans-53.1-42.3173.3-169.8-17670.8-165.710.4111.8L77 N85 Q86 E88L77-R81 VanDerWaalsContact O-CB 3.32Å; L77-R81 WeakPolarHBondContact O-CB 3.27Å; L77-R81 PolarHBondContact O-N 3.39Å; L77-R81 VanDerWaalsContact O-N 3.14Å; R81-N85 PolarHBondContact O-N 3.23Å; R81-N85 VanDerWaalsContact O-N 3.11Å; R81-Q86 HydrophobicContact CG-CB 3.74Å; R81-Q86 WeakPolarHBondContact CG-O 3.5Å; R81-Q86 PolarHBondContact O-N 3.42Å; R81-E88 IonicContact CZ-OE1 3.07Å; R81-E88 IonicContact NH2-OE1 2.71Å; R81-E88 PolarHBondContact NH2-OE1 3.33Å
82G96.1Very high95.3Very high45 Ų4562.7 Ų62.746%0.46436%0.363SS..Hα-helixtrans-64.8-46.5174.600000113.3G78 T79 L80 Y84 N85G78-G82 PolarHBondContact O-N 3.3Å; G78-G82 VanDerWaalsContact O-N 3.17Å; T79-G82 PolarHBondContact O-N 2.86Å; T79-G82 VanDerWaalsContact O-N 3.16Å; L80-G82 PolarHBondContact O-N 2.95Å; G82-Y84 VanDerWaalsContact C-N 3.27Å; G82-Y84 PolarHBondContact O-N 3.32Å; G82-N85 PolarHBondContact O-N 2.97Å; G82-N85 VanDerWaalsContact O-N 3.16Å
83Y97.5Very high95.4Very high55 Ų5561 Ų6122%0.21635%0.353CS..Hα-helixtrans-60.3-36.7178.5-68.3-8.5000113T79 L80 I141 K145T79-Y83 HydrophobicContact CG2-CD1 4.38Å; T79-Y83 HydrophobicContact CG2-CD2 4.44Å; T79-Y83 HydrophobicContact CG2-CE1 3.8Å; T79-Y83 HydrophobicContact CG2-CE2 3.86Å; T79-Y83 PolarHBondContact O-N 2.84Å; L80-Y83 HydrophobicContact CD2-CD2 4.24Å; L80-Y83 PolarHBondContact O-N 3.39Å; Y83-I141 HydrophobicContact CD1-CD1 4.23Å; Y83-I141 HydrophobicContact CD2-CD1 4.44Å; Y83-I141 HydrophobicContact CE1-CD1 4.37Å; Y83-I141 HydrophobicContact CE1-CG2 4.17Å; Y83-I141 HydrophobicContact CE2-CB 4.13Å; Y83-I141 HydrophobicContact CE2-CG2 4.04Å; Y83-I141 HydrophobicContact CG-CD1 4.27Å; Y83-I141 WeakPolarHBondContact OH-CG2 3.41Å; Y83-K145 PolarHBondContact OH-NZ 2.82Å
84Y97.3Very high95.5Very high64 Ų6461.3 Ų61.325%0.25135%0.354SS..THydrogen-bonded Turntrans-91.93.6179.5-67.5-71.8000114.1L80 G82 Q86 Y117 Y122 D136 A138L80-Y84 HydrophobicContact CD2-CE2 4.34Å; L80-Y84 WeakPolarHBondContact O-CD2 3.41Å; L80-Y84 PolarHBondContact O-N 3.15Å; G82-Y84 VanDerWaalsContact C-N 3.27Å; G82-Y84 PolarHBondContact O-N 3.32Å; Y84-Q86 PolarHBondContact O-N 2.89Å; Y84-Y117 AromaticContact CD2-CD1 3.72Å; Y84-Y117 HydrophobicContact CD2-CD1 3.72Å; Y84-Y117 AromaticContact CD2-CE1 3.48Å; Y84-Y117 HydrophobicContact CD2-CE1 3.48Å; Y84-Y117 VanDerWaalsContact CD2-CE1 3.48Å; Y84-Y117 AromaticContact CE2-CD1 3.45Å; Y84-Y117 HydrophobicContact CE2-CD1 3.45Å; Y84-Y117 VanDerWaalsContact CE2-CD1 3.45Å; Y84-Y117 AromaticContact CE2-CE1 3.75Å; Y84-Y117 HydrophobicContact CE2-CE1 3.75Å; Y84-Y117 HydrophobicContact CE2-CG 4.44Å; Y84-Y117 HydrophobicContact CG-CE1 4.42Å; Y84-Y122 HydrophobicContact CE2-CE2 4.21Å; Y84-Y122 VanDerWaalsContact OH-CD2 3.24Å; Y84-Y122 WeakPolarHBondContact OH-CD2 3.48Å; Y84-Y122 VanDerWaalsContact OH-CE2 3.3Å; Y84-Y122 WeakPolarHBondContact OH-CE2 3.18Å; Y84-D136 VanDerWaalsContact CE1-OD2 3.3Å; Y84-D136 WeakPolarHBondContact CE1-OD2 3.33Å; Y84-D136 PolarHBondContact OH-OD1 2.66Å; Y84-D136 PolarHBondContact OH-OD2 2.83Å; Y84-A138 HydrophobicContact CD1-CB 4.08Å; Y84-A138 HydrophobicContact CE1-CB 3.5Å; Y84-A138 HydrophobicContact CE2-CB 4.04Å; Y84-A138 VanDerWaalsContact CZ-CB 3.49Å
85N95.9Very high95.6Very high152 Ų15259.8 Ų59.881%0.81335%0.352SS*.THydrogen-bonded Turntrans5241.2-177.5-55.8-65.4000113.3R81 G82R81-N85 PolarHBondContact O-N 3.23Å; R81-N85 VanDerWaalsContact O-N 3.11Å; G82-N85 PolarHBondContact O-N 2.97Å; G82-N85 VanDerWaalsContact O-N 3.16Å
86Q95.8Very high95.7Very high59 Ų5957.9 Ų57.928%0.27633%0.332SS..  trans-88150.6-177.9-70.4165.8-32.500111.7R81 Y84 H92 Y117 D118R81-Q86 HydrophobicContact CG-CB 3.74Å; R81-Q86 WeakPolarHBondContact CG-O 3.5Å; R81-Q86 PolarHBondContact O-N 3.42Å; Y84-Q86 PolarHBondContact O-N 2.89Å; Q86-H92 PolarHBondContact NE2-CE1 2.93Å; Q86-H92 PolarHBondContact OE1-CE1 2.94Å; Q86-Y117 PolarHBondContact OE1-OH 3.43Å; Q86-D118 PolarHBondContact NE2-OD2 2.86Å
87G90.9Very high95.7Very high52 Ų5256.3 Ų56.354%0.53632%0.323SS..  trans-73.2162.5-179.500000114
88E86.4Confident95.8Very high136 Ų13656.6 Ų56.664%0.63632%0.324SS*.THydrogen-bonded Turntrans-76.4-22.4-174.2-57.9-155.5127.800114.5P14 R81 G90P14-E88 WeakPolarHBondContact CB-O 3.37Å; P14-E88 WeakPolarHBondContact CG-O 3.47Å; R81-E88 IonicContact CZ-OE1 3.07Å; R81-E88 IonicContact NH2-OE1 2.71Å; R81-E88 PolarHBondContact NH2-OE1 3.33Å; E88-G90 VanDerWaalsContact C-N 3.29Å; E88-G90 PolarHBondContact O-N 2.73Å
89D88.4Confident96Very high157 Ų15754.9 Ų54.984%0.8431%0.306SS*.THydrogen-bonded Turntrans-82-9.6-177-58.5-41.8000113.1
90G91.2Very high96.1Very high29 Ų2952.2 Ų52.230%0.29929%0.29SS..  trans-75.3130.9179.400000112.9P14 E88 H92P14-G90 WeakPolarHBondContact CG-O 3.47Å; E88-G90 VanDerWaalsContact C-N 3.29Å; E88-G90 PolarHBondContact O-N 2.73Å; G90-H92 PolarHBondContact O-CD2 2.99Å
91S96.7Very high96.1Very high72 Ų7253 Ų5350%0.50329%0.294SS..  trans-81.1131.3165-177.70000109S12S12-S91 PolarHBondContact O-OG 2.83Å; S12-S91 WeakPolarHBondContact OG-CA 3.41Å
92H98Very high96.2Very high15 Ų1549.5 Ų49.57%0.06928%0.281CS..  trans-128.8151.6-175-65.3-72.4000110.3V11 S12 L77 Q86 G90 Y117 D118V11-H92 WeakPolarHBondContact CA-O 3.41Å; S12-H92 PolarHBondContact N-O 2.62Å; S12-H92 PolarHBondContact OG-N 2.96Å; S12-H92 PolarHBondContact OG-O 2.94Å; L77-H92 HydrophobicContact CD2-CB 4.05Å; Q86-H92 PolarHBondContact NE2-CE1 2.93Å; Q86-H92 PolarHBondContact OE1-CE1 2.94Å; G90-H92 PolarHBondContact O-CD2 2.99Å; H92-Y117 HydrophobicContact CB-CE2 3.87Å; H92-Y117 WeakPolarHBondContact CB-OH 3.49Å; H92-Y117 VanDerWaalsContact CG-OH 3.24Å; H92-Y117 AromaticContact ND1-CZ 3.93Å; H92-Y117 PolarHBondContact ND1-OH 3.23Å; H92-D118 WeakPolarHBondContact CA-OD1 3.18Å; H92-D118 WeakPolarHBondContact CB-OD1 3.46Å; H92-D118 IonicContact CE1-OD2 3.67Å; H92-D118 IonicContact CG-OD1 2.72Å; H92-D118 IonicContact CG-OD2 3.76Å; H92-D118 IonicContact ND1-OD1 3.68Å; H92-D118 IonicContact ND1-OD2 3.26Å; H92-D118 PolarHBondContact ND1-OD2 3.1Å
93T98.6Very high96.3Very high34 Ų3447.5 Ų47.521%0.20926%0.26CS..EExtended strand (participates in β ladder)trans-126128.7-175.2-54.70000111.1T9 S10 V11 Q95 Y117 D118T9-T93 HydrophobicContact CG2-CG2 3.9Å; S10-T93 CarbonylContact O-C 3.57Å; S10-T93 VanDerWaalsContact O-CA 3.27Å; S10-T93 WeakPolarHBondContact O-CA 3.31Å; V11-T93 HydrophobicContact CG2-CG2 4.13Å; T93-Q95 HydrophobicContact CG2-CG 3.91Å; T93-Y117 CarbonylContact O-C 3.59Å; T93-Y117 WeakPolarHBondContact O-CA 3.41Å; T93-Y117 VanDerWaalsContact O-CD2 3.24Å; T93-Y117 WeakPolarHBondContact O-CD2 3.32Å; T93-D118 PolarHBondContact N-OD1 3.24Å; T93-D118 PolarHBondContact O-N 3.46Å
94I98.6Very high96.1Very high7 Ų750.5 Ų50.54%0.03629%0.287CS..EExtended strand (participates in β ladder)trans-104133163.3-64173.5000107.8T9 S10 N76 L77 L80 A116 Y117T9-I94 WeakPolarHBondContact CA-O 3.41Å; S10-I94 PolarHBondContact N-O 3.2Å; S10-I94 PolarHBondContact O-N 2.99Å; N76-I94 HydrophobicContact CB-CD1 3.63Å; L77-I94 HydrophobicContact CB-CD1 4.42Å; L77-I94 HydrophobicContact CD2-CD1 3.96Å; L77-I94 HydrophobicContact CD2-CG1 3.77Å; L77-I94 HydrophobicContact CG-CD1 3.73Å; L77-I94 HydrophobicContact CG-CG1 4.09Å; L80-I94 HydrophobicContact CD1-CD1 3.59Å; L80-I94 HydrophobicContact CD1-CG1 3.69Å; I94-A116 WeakPolarHBondContact CA-O 3.29Å; I94-Y117 HydrophobicContact CG1-CD2 3.86Å; I94-Y117 HydrophobicContact CG1-CE2 4.25Å
95Q98.8Very high96Very high80 Ų8052 Ų5237%0.37430%0.299SS..EExtended strand (participates in β ladder)trans-122.7141.2171.7-64.7170.6-89.500109Y8 T9 T93 D115 A116Y8-Q95 WeakPolarHBondContact O-CA 3.48Å; T9-Q95 HydrophobicContact CG2-CG 4.08Å; T93-Q95 HydrophobicContact CG2-CG 3.91Å; Q95-D115 CarbonylContact O-C 3.57Å; Q95-D115 VanDerWaalsContact O-CA 3.28Å; Q95-D115 WeakPolarHBondContact O-CA 3.48Å; Q95-A116 HydrophobicContact CB-CB 4.29Å; Q95-A116 PolarHBondContact N-O 3.25Å; Q95-A116 PolarHBondContact O-N 3.14Å
96R98.5Very high95.9Very high20 Ų2045.4 Ų45.48%0.07527%0.267CS..EExtended strand (participates in β ladder)trans-132.4135.7175.3169.2173.6-70178.20.7109.6F7 Y8 H69 Y98 Q114 D115F7-R96 CarbonylContact C-O 3.58Å; F7-R96 WeakPolarHBondContact CA-O 3.28Å; Y8-R96 PolarHBondContact N-O 2.96Å; Y8-R96 PolarHBondContact O-N 3.46Å; H69-R96 PolarHBondContact NE2-NH1 3.48Å; R96-Y98 HydrophobicContact CG-CD1 4.16Å; R96-Q114 CarbonylContact C-O 3.56Å; R96-Q114 WeakPolarHBondContact CA-O 3.35Å; R96-D115 WeakPolarHBondContact CB-OD1 3.43Å; R96-D115 VanDerWaalsContact CG-OD1 3.23Å; R96-D115 WeakPolarHBondContact CG-OD1 3.03Å; R96-D115 IonicContact CZ-OD1 2.78Å; R96-D115 IonicContact CZ-OD2 3.49Å; R96-D115 IonicContact NE-OD1 3.3Å; R96-D115 PolarHBondContact NE-OD1 3.13Å; R96-D115 IonicContact NE-OD2 3.48Å; R96-D115 PolarHBondContact NE-OD2 2.96Å; R96-D115 IonicContact NH2-OD1 3.9Å; R96-D115 IonicContact NH2-OD2 2.79Å; R96-D115 PolarHBondContact NH2-OD2 3.2Å
97M98.6Very high96Very high18 Ų1850.6 Ų50.69%0.08928%0.284CS..EExtended strand (participates in β ladder)trans-123.1131.1167-172.6-79-69.100109Y6 F7 Y112 Q113 Q114Y6-M97 WeakPolarHBondContact O-CA 3.4Å; F7-M97 HydrophobicContact CD1-CB 3.93Å; F7-M97 HydrophobicContact CD1-CG 3.6Å; F7-M97 HydrophobicContact CE1-CB 4.03Å; F7-M97 HydrophobicContact CE1-CG 3.29Å; F7-M97 HydrophobicContact CG-CG 4.41Å; F7-M97 HydrophobicContact CZ-CG 3.86Å; M97-Y112 HydrophobicContact CE-CD1 4.28Å; M97-Y112 HydrophobicContact CE-CG 4.16Å; M97-Q113 CarbonylContact O-C 3.51Å; M97-Q113 WeakPolarHBondContact O-CA 3.43Å; M97-Q114 HydrophobicContact CB-CG 3.98Å; M97-Q114 VanDerWaalsContact CE-CD 3.46Å; M97-Q114 HydrophobicContact CE-CG 3.92Å; M97-Q114 PolarHBondContact N-O 3.21Å; M97-Q114 PolarHBondContact O-N 3.18Å
98Y98.8Very high96.4Very high17 Ų1751 Ų517%0.06727%0.272CS..EExtended strand (participates in β ladder)trans-144.9158.3169.772-92.8000110.9R5 Y6 Y8 R96 Y112 W155 Y158R5-Y98 WeakPolarHBondContact CA-O 3.3Å; Y6-Y98 VanDerWaalsContact CB-CZ 3.47Å; Y6-Y98 HydrophobicContact CD2-CD2 4.3Å; Y6-Y98 AromaticContact CD2-CE2 3.46Å; Y6-Y98 HydrophobicContact CD2-CE2 3.46Å; Y6-Y98 VanDerWaalsContact CD2-CE2 3.46Å; Y6-Y98 AromaticContact CD2-CZ 3.63Å; Y6-Y98 WeakPolarHBondContact CD2-OH 3.39Å; Y6-Y98 HydrophobicContact CE2-CE2 4.24Å; Y6-Y98 HydrophobicContact CG-CE1 4.31Å; Y6-Y98 AromaticContact CG-CE2 3.99Å; Y6-Y98 HydrophobicContact CG-CE2 3.99Å; Y6-Y98 AromaticContact CG-CZ 3.67Å; Y6-Y98 PolarHBondContact N-O 3.19Å; Y6-Y98 PolarHBondContact O-N 3.16Å; Y6-Y98 VanDerWaalsContact O-N 3.1Å; Y8-Y98 HydrophobicContact CD2-CE1 4.42Å; Y8-Y98 HydrophobicContact CE1-CE1 4.17Å; Y8-Y98 AromaticContact CE2-CE1 3.8Å; Y8-Y98 HydrophobicContact CE2-CE1 3.8Å; Y8-Y98 AromaticContact CZ-CE1 3.66Å; Y8-Y98 PolarHBondContact OH-OH 3.24Å; R96-Y98 HydrophobicContact CG-CD1 4.16Å; Y98-Y112 CarbonylContact C-O 3.57Å; Y98-Y112 WeakPolarHBondContact CA-O 3.29Å; Y98-Y112 VanDerWaalsContact CB-O 3.29Å; Y98-Y112 WeakPolarHBondContact CB-O 3.31Å; Y98-W155 HydrophobicContact CD1-CH2 4.16Å; Y98-W155 HydrophobicContact CD1-CZ3 4.43Å; Y98-W155 HydrophobicContact CD2-CH2 4.41Å; Y98-W155 AromaticContact CD2-CZ3 3.9Å; Y98-W155 HydrophobicContact CD2-CZ3 3.9Å; Y98-W155 HydrophobicContact CG-CH2 4.02Å; Y98-W155 AromaticContact CG-CZ3 3.84Å; Y98-W155 HydrophobicContact CG-CZ3 3.84Å; Y98-Y158 AromaticContact CD2-CE1 3.82Å; Y98-Y158 HydrophobicContact CD2-CE1 3.82Å; Y98-Y158 AromaticContact CE2-CE1 3.72Å; Y98-Y158 HydrophobicContact CE2-CE1 3.72Å; Y98-Y158 AromaticContact CE2-CZ 3.96Å
99G98.7Very high96.9Very high0 Ų049.5 Ų49.50%027%0.267CS..EExtended strand (participates in β ladder)trans161.6-175.8179.300000113.9M4 G111 Y112 L159M4-G99 CarbonylContact O-C 3.51Å; M4-G99 WeakPolarHBondContact O-CA 3.27Å; G99-G111 CarbonylContact O-C 3.59Å; G99-G111 WeakPolarHBondContact O-CA 3.13Å; G99-Y112 PolarHBondContact N-O 3.14Å; G99-Y112 PolarHBondContact O-N 3.3Å; G99-L159 WeakPolarHBondContact O-CD2 3.4Å
100C98.8Very high97.4Very high0 Ų046.4 Ų46.40%024%0.244CC..EExtended strand (participates in β ladder)trans-137.2151.7-176.156.20000111.5S3 M4 F108 R110 C163S3-C100 WeakPolarHBondContact CA-O 3.46Å; M4-C100 PolarHBondContact N-O 3Å; M4-C100 PolarHBondContact O-N 3.42Å; C100-F108 HydrophobicContact CB-CD2 4.43Å; C100-F108 HydrophobicContact CB-CE2 4.16Å; C100-R110 CarbonylContact C-O 3.45Å; C100-R110 VanDerWaalsContact CA-O 3.3Å; C100-R110 WeakPolarHBondContact CA-O 3.49Å; C100-C163 HydrophobicContact CB-CB 3.88Å; C100-C163 WeakPolarHBondContact CB-SG 3.3Å; C100-C163 PolarHBondContact N-SG 3.26Å; C100-C163 WeakPolarHBondContact SG-CB 3.44Å; C100-C163 CovalentContact SG-SG 2.04Å; C100-C163 PolarHBondContact SG-SG 3.49Å
101D98.6Very high97.7Very high27 Ų2745.3 Ų45.314%0.14423%0.232CC..EExtended strand (participates in β ladder)trans-112.3143.2173.4-60.1-12.5000109.6H2 S3 R5 L109 R110 Y112H2-D101 CarbonylContact O-C 3.59Å; H2-D101 WeakPolarHBondContact O-CA 3.38Å; S3-D101 WeakPolarHBondContact CB-OD1 3.5Å; R5-D101 IonicContact CZ-OD1 3.4Å; R5-D101 IonicContact NE-OD1 3.71Å; R5-D101 PolarHBondContact NE-OD1 3.43Å; R5-D101 VanDerWaalsContact NH2-CG 3.29Å; R5-D101 IonicContact NH2-OD1 3.12Å; R5-D101 PolarHBondContact NH2-OD1 3.12Å; R5-D101 IonicContact NH2-OD2 2.72Å; R5-D101 PolarHBondContact NH2-OD2 3.15Å; R5-D101 VanDerWaalsContact NH2-OD2 3.07Å; D101-L109 HydrophobicContact CB-CB 4.36Å; D101-L109 PolarHBondContact O-N 3.45Å; D101-R110 HydrophobicContact CB-CB 4.41Å; D101-R110 PolarHBondContact N-O 2.84Å; D101-Y112 WeakPolarHBondContact OD2-CE2 3.49Å; D101-Y112 PolarHBondContact OD2-OH 3.21Å
102V98.6Very high97.8Very high0 Ų043.8 Ų43.80%022%0.216CC..EExtended strand (participates in β ladder)trans-125.8146.2175.2-61.80000111.6S1 H2 R107 V164 L167 L171S1-V102 CarbonylContact C-O 3.54Å; S1-V102 WeakPolarHBondContact CA-O 3.36Å; S1-V102 WeakPolarHBondContact CB-O 3.43Å; H2-V102 HydrophobicContact CB-CG2 4.01Å; H2-V102 PolarHBondContact N-O 3.43Å; H2-V102 PolarHBondContact O-N 2.83Å; V102-R107 CarbonylContact C-O 3.59Å; V102-R107 WeakPolarHBondContact CA-O 3.45Å; V102-R107 WeakPolarHBondContact CB-O 3.31Å; V102-V164 HydrophobicContact CG1-CB 4.39Å; V102-V164 HydrophobicContact CG1-CG1 3.9Å; V102-V164 HydrophobicContact CG1-CG2 4.03Å; V102-L167 HydrophobicContact CB-CD2 4.34Å; V102-L167 HydrophobicContact CG1-CD2 3.93Å; V102-L167 HydrophobicContact CG2-CD2 3.63Å; V102-L167 HydrophobicContact CG2-CG 4.18Å; V102-L171 HydrophobicContact CG2-CD1 4.48Å
103G97.4Very high97.8Very high3 Ų343.1 Ų43.13%0.03121%0.213CC..  trans-72.5176.5176.200000112.3D105 G106 R107 L109G103-D105 PolarHBondContact O-N 2.68Å; G103-G106 WeakPolarHBondContact O-CA 3.49Å; G103-G106 PolarHBondContact O-N 2.9Å; G103-R107 PolarHBondContact N-O 2.84Å; G103-L109 VanDerWaalsContact CA-CD1 3.47Å
104P94.2Very high97.8Very high119 Ų11945.2 Ų45.277%0.77322%0.22SC*.THydrogen-bonded Turntrans-58.8-26.8175.3-23.234.4000113.5G106P104-G106 PolarHBondContact O-N 2.82Å
105D94.6Very high97.8Very high94 Ų9445.6 Ų45.650%0.50322%0.222SC..THydrogen-bonded Turntrans-84.15.3174.468.5-12.6000113.3G103 R107G103-D105 PolarHBondContact O-N 2.68Å; D105-R107 PolarHBondContact O-N 3.17Å; D105-R107 WeakPolarHBondContact OD1-CB 3.19Å; D105-R107 PolarHBondContact OD1-N 3.27Å; D105-R107 WeakPolarHBondContact OD2-CD 3.44Å; D105-R107 VanDerWaalsContact OD2-CG 3.25Å; D105-R107 WeakPolarHBondContact OD2-CG 3.43Å; D105-R107 IonicContact OD2-CZ 3.84Å; D105-R107 IonicContact OD2-NE 3.54Å; D105-R107 PolarHBondContact OD2-NE 2.82Å
106G94.8Very high97.8Very high15 Ų1542.5 Ų42.516%0.15521%0.21CC..SBendtrans72.75.5-178.100000114.4G103 P104 R168G103-G106 WeakPolarHBondContact O-CA 3.49Å; G103-G106 PolarHBondContact O-N 2.9Å; P104-G106 PolarHBondContact O-N 2.82Å; G106-R168 PolarHBondContact O-NE 3.44Å; G106-R168 PolarHBondContact O-NH2 2.89Å
107R97.4Very high97.8Very high168 Ų16842.1 Ų42.163%0.63421%0.209SC*.  trans-76.8148.7178.7-65.5-175.7-164.5176.53.9111.3V102 G103 D105 L109V102-R107 CarbonylContact C-O 3.59Å; V102-R107 WeakPolarHBondContact CA-O 3.45Å; V102-R107 WeakPolarHBondContact CB-O 3.31Å; G103-R107 PolarHBondContact N-O 2.84Å; D105-R107 PolarHBondContact O-N 3.17Å; D105-R107 WeakPolarHBondContact OD1-CB 3.19Å; D105-R107 PolarHBondContact OD1-N 3.27Å; D105-R107 WeakPolarHBondContact OD2-CD 3.44Å; D105-R107 VanDerWaalsContact OD2-CG 3.25Å; D105-R107 WeakPolarHBondContact OD2-CG 3.43Å; D105-R107 IonicContact OD2-CZ 3.84Å; D105-R107 IonicContact OD2-NE 3.54Å; D105-R107 PolarHBondContact OD2-NE 2.82Å; R107-L109 PolarHBondContact O-N 3.45Å
108F98.5Very high97.8Very high61 Ų6144.2 Ų44.227%0.26822%0.22SC..EExtended strand (participates in β ladder)trans-54.5130.4175.2-179.5-101.7000111.1C100 R110 G111 L129 L159 E160 V164C100-F108 HydrophobicContact CB-CD2 4.43Å; C100-F108 HydrophobicContact CB-CE2 4.16Å; F108-R110 VanDerWaalsContact CE2-C 3.44Å; F108-R110 WeakPolarHBondContact CE2-O 3.45Å; F108-G111 VanDerWaalsContact CZ-N 3.29Å; F108-L129 HydrophobicContact CE1-CD1 4.1Å; F108-L129 HydrophobicContact CZ-CD1 3.76Å; F108-L159 HydrophobicContact CE2-CB 4.48Å; F108-L159 WeakPolarHBondContact CE2-O 3.49Å; F108-E160 HydrophobicContact CD1-CG 4.15Å; F108-E160 HydrophobicContact CE1-CG 3.94Å; F108-E160 HydrophobicContact CE2-CG 4.39Å; F108-E160 HydrophobicContact CG-CG 4.46Å; F108-E160 HydrophobicContact CZ-CG 4.07Å; F108-V164 HydrophobicContact CB-CG2 4.02Å; F108-V164 HydrophobicContact CD2-CG2 3.67Å; F108-V164 HydrophobicContact CG-CG2 4.33Å
109L98Very high97.8Very high103 Ų10346.2 Ų46.254%0.53925%0.246SC..EExtended strand (participates in β ladder)trans-111.1-48.8173.7-68.8-179.2000111.8D101 G103 R107D101-L109 HydrophobicContact CB-CB 4.36Å; D101-L109 PolarHBondContact O-N 3.45Å; G103-L109 VanDerWaalsContact CA-CD1 3.47Å; R107-L109 PolarHBondContact O-N 3.45Å
110R98.1Very high97.7Very high93 Ų9353.9 Ų53.935%0.35128%0.279SS..EExtended strand (participates in β ladder)trans-155.9148.2-172.5-172.8163169.5147.76.1111.4C100 D101 F108 Y112 E127C100-R110 CarbonylContact C-O 3.45Å; C100-R110 VanDerWaalsContact CA-O 3.3Å; C100-R110 WeakPolarHBondContact CA-O 3.49Å; D101-R110 HydrophobicContact CB-CB 4.41Å; D101-R110 PolarHBondContact N-O 2.84Å; F108-R110 VanDerWaalsContact CE2-C 3.44Å; F108-R110 WeakPolarHBondContact CE2-O 3.45Å; R110-Y112 HydrophobicContact CB-CE2 4.16Å; R110-Y112 WeakPolarHBondContact CD-OH 3.43Å; R110-Y112 HydrophobicContact CG-CE1 4.09Å; R110-Y112 HydrophobicContact CG-CE2 3.81Å; R110-Y112 PolarHBondContact NE-OH 2.99Å; R110-E127 VanDerWaalsContact CZ-CD 3.45Å; R110-E127 IonicContact CZ-OE1 3.6Å; R110-E127 IonicContact NH1-OE1 3.54Å; R110-E127 PolarHBondContact NH1-OE1 3.46Å; R110-E127 IonicContact NH1-OE2 2.76Å; R110-E127 VanDerWaalsContact NH2-CD 3.34Å; R110-E127 VanDerWaalsContact NH2-CG 3.35Å; R110-E127 IonicContact NH2-OE1 3.3Å; R110-E127 PolarHBondContact NH2-OE1 2.71Å
111G98.4Very high97.7Very high5 Ų559.9 Ų59.95%0.05231%0.312CS..EExtended strand (participates in β ladder)trans-122.3153.2174.900000110.4G99 F108G99-G111 CarbonylContact O-C 3.59Å; G99-G111 WeakPolarHBondContact O-CA 3.13Å; F108-G111 VanDerWaalsContact CZ-N 3.29Å
112Y98.4Very high97.7Very high41 Ų4159.1 Ų59.116%0.16131%0.307CS..EExtended strand (participates in β ladder)trans-136.4140.2-179-51.3-97.4000109.6R5 M97 Y98 G99 D101 R110R5-Y112 VanDerWaalsContact NH2-CZ 3.32Å; R5-Y112 PolarHBondContact NH2-OH 2.92Å; M97-Y112 HydrophobicContact CE-CD1 4.28Å; M97-Y112 HydrophobicContact CE-CG 4.16Å; Y98-Y112 CarbonylContact C-O 3.57Å; Y98-Y112 WeakPolarHBondContact CA-O 3.29Å; Y98-Y112 VanDerWaalsContact CB-O 3.29Å; Y98-Y112 WeakPolarHBondContact CB-O 3.31Å; G99-Y112 PolarHBondContact N-O 3.14Å; G99-Y112 PolarHBondContact O-N 3.3Å; D101-Y112 WeakPolarHBondContact OD2-CE2 3.49Å; D101-Y112 PolarHBondContact OD2-OH 3.21Å; R110-Y112 HydrophobicContact CB-CE2 4.16Å; R110-Y112 WeakPolarHBondContact CD-OH 3.43Å; R110-Y112 HydrophobicContact CG-CE1 4.09Å; R110-Y112 HydrophobicContact CG-CE2 3.81Å; R110-Y112 PolarHBondContact NE-OH 2.99Å
113Q98.4Very high97.8Very high1 Ų159.3 Ų59.31%0.00531%0.308CS..EExtended strand (participates in β ladder)trans-150.5119.6162.9-166.5-64.4-4200105.9M97 D115 L125 W155M97-Q113 CarbonylContact O-C 3.51Å; M97-Q113 WeakPolarHBondContact O-CA 3.43Å; Q113-D115 PolarHBondContact NE2-OD1 3.18Å; Q113-L125 HydrophobicContact CB-CB 3.93Å; Q113-L125 HydrophobicContact CB-CD2 4.2Å; Q113-L125 PolarHBondContact O-N 3.29Å; Q113-W155 HydrophobicContact CB-CD2 4.23Å; Q113-W155 HydrophobicContact CB-CE3 4.3Å; Q113-W155 HydrophobicContact CG-CD2 3.65Å; Q113-W155 VanDerWaalsContact CG-CE2 3.5Å; Q113-W155 HydrophobicContact CG-CE3 3.9Å; Q113-W155 HydrophobicContact CG-CG 4.25Å; Q113-W155 HydrophobicContact CG-CH2 3.88Å; Q113-W155 HydrophobicContact CG-CZ2 3.63Å; Q113-W155 HydrophobicContact CG-CZ3 4.01Å
114Q98.5Very high97.8Very high78 Ų7860.6 Ų60.636%0.36432%0.318SS..EExtended strand (participates in β ladder)trans-148138.8178.761.8-167.759.300110.3R96 M97 I123 A124R96-Q114 CarbonylContact C-O 3.56Å; R96-Q114 WeakPolarHBondContact CA-O 3.35Å; M97-Q114 HydrophobicContact CB-CG 3.98Å; M97-Q114 VanDerWaalsContact CE-CD 3.46Å; M97-Q114 HydrophobicContact CE-CG 3.92Å; M97-Q114 PolarHBondContact N-O 3.21Å; M97-Q114 PolarHBondContact O-N 3.18Å; Q114-I123 WeakPolarHBondContact CA-O 3.36Å; Q114-A124 HydrophobicContact CB-CB 3.95Å
115D98.6Very high98Very high14 Ų1455.7 Ų55.78%0.07529%0.285CS..EExtended strand (participates in β ladder)trans-116.6144.1176.6-66.1-4000109.6Q95 R96 Q113 Y122 I123Q95-D115 CarbonylContact O-C 3.57Å; Q95-D115 VanDerWaalsContact O-CA 3.28Å; Q95-D115 WeakPolarHBondContact O-CA 3.48Å; R96-D115 WeakPolarHBondContact CB-OD1 3.43Å; R96-D115 VanDerWaalsContact CG-OD1 3.23Å; R96-D115 WeakPolarHBondContact CG-OD1 3.03Å; R96-D115 IonicContact CZ-OD1 2.78Å; R96-D115 IonicContact CZ-OD2 3.49Å; R96-D115 IonicContact NE-OD1 3.3Å; R96-D115 PolarHBondContact NE-OD1 3.13Å; R96-D115 IonicContact NE-OD2 3.48Å; R96-D115 PolarHBondContact NE-OD2 2.96Å; R96-D115 IonicContact NH2-OD1 3.9Å; R96-D115 IonicContact NH2-OD2 2.79Å; R96-D115 PolarHBondContact NH2-OD2 3.2Å; Q113-D115 PolarHBondContact NE2-OD1 3.18Å; D115-Y122 HydrophobicContact CB-CD1 4.49Å; D115-Y122 WeakPolarHBondContact O-CA 3.2Å; D115-Y122 WeakPolarHBondContact O-CB 3.15Å; D115-Y122 PolarHBondContact O-N 2.83Å; D115-I123 HydrophobicContact CB-CG2 4.15Å; D115-I123 PolarHBondContact N-O 2.95Å; D115-I123 PolarHBondContact O-N 3.3Å
116A98.8Very high98.2Very high16 Ų1653.2 Ų53.213%0.13227%0.272CS..EExtended strand (participates in β ladder)trans-128148.8174.600000110.1I94 Q95 K120I94-A116 WeakPolarHBondContact CA-O 3.29Å; Q95-A116 HydrophobicContact CB-CB 4.29Å; Q95-A116 PolarHBondContact N-O 3.25Å; Q95-A116 PolarHBondContact O-N 3.14Å; A116-K120 CarbonylContact C-O 3.59Å; A116-K120 WeakPolarHBondContact CA-O 3.24Å; A116-K120 WeakPolarHBondContact CB-O 3.37Å
117Y98.7Very high98.4Very high11 Ų1159 Ų594%0.04330%0.295CS..EExtended strand (participates in β ladder)trans-128.3128.2178.2-174.2-120.5000110.3L77 L80 Y84 Q86 H92 T93 I94 G119 K120L77-Y117 HydrophobicContact CD2-CE2 4.34Å; L80-Y117 HydrophobicContact CB-CD1 4.39Å; L80-Y117 HydrophobicContact CB-CD2 4.2Å; L80-Y117 HydrophobicContact CB-CE1 4.01Å; L80-Y117 HydrophobicContact CB-CE2 3.83Å; L80-Y117 HydrophobicContact CB-CG 4.46Å; L80-Y117 HydrophobicContact CD1-CD2 3.46Å; L80-Y117 VanDerWaalsContact CD1-CD2 3.46Å; L80-Y117 HydrophobicContact CD1-CE2 3.82Å; L80-Y117 HydrophobicContact CD1-CG 3.86Å; L80-Y117 HydrophobicContact CG-CD2 4.44Å; L80-Y117 HydrophobicContact CG-CE2 4.49Å; Y84-Y117 AromaticContact CD2-CD1 3.72Å; Y84-Y117 HydrophobicContact CD2-CD1 3.72Å; Y84-Y117 AromaticContact CD2-CE1 3.48Å; Y84-Y117 HydrophobicContact CD2-CE1 3.48Å; Y84-Y117 VanDerWaalsContact CD2-CE1 3.48Å; Y84-Y117 AromaticContact CE2-CD1 3.45Å; Y84-Y117 HydrophobicContact CE2-CD1 3.45Å; Y84-Y117 VanDerWaalsContact CE2-CD1 3.45Å; Y84-Y117 AromaticContact CE2-CE1 3.75Å; Y84-Y117 HydrophobicContact CE2-CE1 3.75Å; Y84-Y117 HydrophobicContact CE2-CG 4.44Å; Y84-Y117 HydrophobicContact CG-CE1 4.42Å; Q86-Y117 PolarHBondContact OE1-OH 3.43Å; H92-Y117 HydrophobicContact CB-CE2 3.87Å; H92-Y117 WeakPolarHBondContact CB-OH 3.49Å; H92-Y117 VanDerWaalsContact CG-OH 3.24Å; H92-Y117 AromaticContact ND1-CZ 3.93Å; H92-Y117 PolarHBondContact ND1-OH 3.23Å; T93-Y117 CarbonylContact O-C 3.59Å; T93-Y117 WeakPolarHBondContact O-CA 3.41Å; T93-Y117 VanDerWaalsContact O-CD2 3.24Å; T93-Y117 WeakPolarHBondContact O-CD2 3.32Å; I94-Y117 HydrophobicContact CG1-CD2 3.86Å; I94-Y117 HydrophobicContact CG1-CE2 4.25Å; Y117-G119 PolarHBondContact O-N 2.72Å; Y117-K120 PolarHBondContact N-O 3.17Å; Y117-K120 PolarHBondContact O-N 3.01Å
118D98.1Very high98.4Very high62 Ų6254.8 Ų54.833%0.33229%0.285SS..THydrogen-bonded Turntrans49.839.8-175.8-66.5-20.1000113.3Q86 H92 T93 K120Q86-D118 PolarHBondContact NE2-OD2 2.86Å; H92-D118 WeakPolarHBondContact CA-OD1 3.18Å; H92-D118 WeakPolarHBondContact CB-OD1 3.46Å; H92-D118 IonicContact CE1-OD2 3.67Å; H92-D118 IonicContact CG-OD1 2.72Å; H92-D118 IonicContact CG-OD2 3.76Å; H92-D118 IonicContact ND1-OD1 3.68Å; H92-D118 IonicContact ND1-OD2 3.26Å; H92-D118 PolarHBondContact ND1-OD2 3.1Å; T93-D118 PolarHBondContact N-OD1 3.24Å; T93-D118 PolarHBondContact O-N 3.46Å; D118-K120 VanDerWaalsContact C-N 3.29Å; D118-K120 PolarHBondContact O-N 2.91Å
119G97.5Very high98.4Very high59 Ų5952.2 Ų52.261%0.60827%0.274SS*.THydrogen-bonded Turntrans76.68.3178.400000115.2Y117Y117-G119 PolarHBondContact O-N 2.72Å
120K98.4Very high98.4Very high161 Ų16155.3 Ų55.370%0.728%0.279SS*.EExtended strand (participates in β ladder)trans-114146176.1-62179.2-177.5176.90110.6A116 Y117 D118 Y122A116-K120 CarbonylContact C-O 3.59Å; A116-K120 WeakPolarHBondContact CA-O 3.24Å; A116-K120 WeakPolarHBondContact CB-O 3.37Å; Y117-K120 PolarHBondContact N-O 3.17Å; Y117-K120 PolarHBondContact O-N 3.01Å; D118-K120 VanDerWaalsContact C-N 3.29Å; D118-K120 PolarHBondContact O-N 2.91Å; K120-Y122 PolarHBondContact O-N 3.12Å
121D98.7Very high98.4Very high127 Ų12752.8 Ų52.868%0.67928%0.275SS*.EExtended strand (participates in β ladder)trans-53.5136.8173.8-66.3-30.4000110.5A135D121-A135 HydrophobicContact CB-CB 4.3Å; D121-A135 WeakPolarHBondContact O-CB 3.14Å
122Y98.8Very high98.4Very high10 Ų1053 Ų534%0.03928%0.275CS..EExtended strand (participates in β ladder)trans-115-61.9178.9-179.6-114.8000110.7L80 Y84 D115 K120 A135 A138 A139 T142L80-Y122 HydrophobicContact CD2-CD2 4.41Å; L80-Y122 HydrophobicContact CD2-CE1 3.79Å; L80-Y122 HydrophobicContact CD2-CE2 3.66Å; L80-Y122 WeakPolarHBondContact CD2-OH 3.37Å; Y84-Y122 HydrophobicContact CE2-CE2 4.21Å; Y84-Y122 VanDerWaalsContact OH-CD2 3.24Å; Y84-Y122 WeakPolarHBondContact OH-CD2 3.48Å; Y84-Y122 VanDerWaalsContact OH-CE2 3.3Å; Y84-Y122 WeakPolarHBondContact OH-CE2 3.18Å; D115-Y122 HydrophobicContact CB-CD1 4.49Å; D115-Y122 WeakPolarHBondContact O-CA 3.2Å; D115-Y122 WeakPolarHBondContact O-CB 3.15Å; D115-Y122 PolarHBondContact O-N 2.83Å; K120-Y122 PolarHBondContact O-N 3.12Å; Y122-A135 WeakPolarHBondContact O-CB 3.42Å; Y122-A135 PolarHBondContact O-N 3.08Å; Y122-A138 PolarHBondContact OH-O 2.89Å; Y122-A139 HydrophobicContact CD2-CB 3.74Å; Y122-A139 VanDerWaalsContact CE2-CA 3.42Å; Y122-A139 HydrophobicContact CE2-CB 3.59Å; Y122-A139 HydrophobicContact CG-CB 4.34Å; Y122-A139 WeakPolarHBondContact O-CB 3.44Å; Y122-T142 HydrophobicContact CE1-CG2 4.2Å; Y122-T142 WeakPolarHBondContact OH-CB 3.41Å; Y122-T142 PolarHBondContact OH-OG1 2.83Å
123I98.8Very high98.4Very high4 Ų454.7 Ų54.72%0.02129%0.289CS..EExtended strand (participates in β ladder)trans-150.3142.3178.4-164.7170.3000110.4Q114 D115 W132 T133 T142 Q143 W146Q114-I123 WeakPolarHBondContact CA-O 3.36Å; D115-I123 HydrophobicContact CB-CG2 4.15Å; D115-I123 PolarHBondContact N-O 2.95Å; D115-I123 PolarHBondContact O-N 3.3Å; I123-W132 HydrophobicContact CD1-CB 4.23Å; I123-W132 HydrophobicContact CD1-CD2 4.46Å; I123-W132 HydrophobicContact CD1-CE3 4.25Å; I123-W132 HydrophobicContact CD1-CG 4.48Å; I123-W132 HydrophobicContact CG1-CB 4.34Å; I123-W132 HydrophobicContact CG1-CE3 4.08Å; I123-T133 WeakPolarHBondContact CA-O 3.17Å; I123-T142 HydrophobicContact CD1-CG2 4.27Å; I123-Q143 HydrophobicContact CD1-CB 3.91Å; I123-W146 HydrophobicContact CD1-CE3 4.01Å; I123-W146 HydrophobicContact CD1-CZ3 4.25Å; I123-W146 HydrophobicContact CG2-CH2 3.96Å; I123-W146 HydrophobicContact CG2-CZ3 3.73Å
124A98.8Very high98.4Very high31 Ų3155.8 Ų55.826%0.25630%0.299SS..EExtended strand (participates in β ladder)trans-135.2140.3178.600000111.8Q114 W132 T133Q114-A124 HydrophobicContact CB-CB 3.95Å; A124-W132 CarbonylContact O-C 3.54Å; A124-W132 WeakPolarHBondContact O-CA 3.46Å; A124-T133 PolarHBondContact N-O 2.85Å; A124-T133 PolarHBondContact O-N 2.88Å
125L98.8Very high98.4Very high15 Ų1554.9 Ų54.98%0.07930%0.304CS..EExtended strand (participates in β ladder)trans-72.6127.5169.3-175.665.4000108.9Q113 L129 W132 A152 W155 L159Q113-L125 HydrophobicContact CB-CB 3.93Å; Q113-L125 HydrophobicContact CB-CD2 4.2Å; Q113-L125 PolarHBondContact O-N 3.29Å; L125-L129 HydrophobicContact CD2-CB 4.5Å; L125-L129 HydrophobicContact CD2-CD2 3.76Å; L125-L129 HydrophobicContact CG-CD2 4.24Å; L125-W132 HydrophobicContact CB-CE3 3.99Å; L125-W132 HydrophobicContact CB-CH2 4.04Å; L125-W132 HydrophobicContact CB-CZ3 3.58Å; L125-W132 HydrophobicContact CD1-CD2 4.16Å; L125-W132 HydrophobicContact CD1-CE3 4.23Å; L125-W132 HydrophobicContact CD1-CH2 3.96Å; L125-W132 HydrophobicContact CD1-CZ2 3.89Å; L125-W132 HydrophobicContact CD1-CZ3 4.11Å; L125-W132 HydrophobicContact CG-CH2 4.47Å; L125-W132 HydrophobicContact CG-CZ3 4.41Å; L125-A152 HydrophobicContact CD1-CB 3.99Å; L125-W155 HydrophobicContact CD2-CB 3.92Å; L125-L159 HydrophobicContact CD2-CD1 3.9Å
126N98.6Very high98.4Very high42 Ų4257 Ų5723%0.22532%0.316CS..  trans-71.8163-179.4-68-29000111.6D128 L129 S131 T133N126-D128 PolarHBondContact O-N 3.03Å; N126-D128 VanDerWaalsContact O-N 3.08Å; N126-L129 PolarHBondContact O-N 2.81Å; N126-S131 WeakPolarHBondContact CB-O 3.33Å; N126-S131 WeakPolarHBondContact CB-OG 3.41Å; N126-S131 PolarHBondContact N-O 3.03Å; N126-S131 PolarHBondContact ND2-O 3.21Å; N126-S131 PolarHBondContact ND2-OG 3.38Å; N126-T133 PolarHBondContact ND2-OG1 2.89Å; N126-T133 WeakPolarHBondContact OD1-CB 3.3Å; N126-T133 PolarHBondContact OD1-OG1 3.05Å
127E97.9Very high98.4Very high137 Ų13762.6 Ų62.664%0.6434%0.341SS*.THydrogen-bonded Turntrans-59.5-22.5-179.3-63.9-175.6-17400113.6R110 L129R110-E127 VanDerWaalsContact CZ-CD 3.45Å; R110-E127 IonicContact CZ-OE1 3.6Å; R110-E127 IonicContact NH1-OE1 3.54Å; R110-E127 PolarHBondContact NH1-OE1 3.46Å; R110-E127 IonicContact NH1-OE2 2.76Å; R110-E127 VanDerWaalsContact NH2-CD 3.34Å; R110-E127 VanDerWaalsContact NH2-CG 3.35Å; R110-E127 IonicContact NH2-OE1 3.3Å; R110-E127 PolarHBondContact NH2-OE1 2.71Å; E127-L129 PolarHBondContact O-N 2.82Å
128D97.8Very high98.3Very high79 Ų7962.6 Ų62.642%0.42234%0.343SS..THydrogen-bonded Turntrans-72-10.1174.969.54000113.8N126 R130 S131N126-D128 PolarHBondContact O-N 3.03Å; N126-D128 VanDerWaalsContact O-N 3.08Å; D128-R130 WeakPolarHBondContact O-CG 3.35Å; D128-R130 PolarHBondContact O-N 2.81Å; D128-R130 PolarHBondContact OD1-N 3.32Å; D128-S131 VanDerWaalsContact CG-OG 3.26Å; D128-S131 PolarHBondContact OD1-N 2.84Å; D128-S131 PolarHBondContact OD1-OG 2.83Å; D128-S131 VanDerWaalsContact OD1-OG 3.12Å; D128-S131 PolarHBondContact OD2-OG 3.42Å
129L98.3Very high98.3Very high7 Ų759.6 Ų59.64%0.03733%0.327CS..SBendtrans53.429.7-174.6-51.7179.3000113.8F108 L125 N126 E127 R156 L159 E160F108-L129 HydrophobicContact CE1-CD1 4.1Å; F108-L129 HydrophobicContact CZ-CD1 3.76Å; L125-L129 HydrophobicContact CD2-CB 4.5Å; L125-L129 HydrophobicContact CD2-CD2 3.76Å; L125-L129 HydrophobicContact CG-CD2 4.24Å; N126-L129 PolarHBondContact O-N 2.81Å; E127-L129 PolarHBondContact O-N 2.82Å; L129-R156 HydrophobicContact CB-CB 4.05Å; L129-R156 HydrophobicContact CB-CG 3.92Å; L129-R156 HydrophobicContact CD1-CG 4.1Å; L129-L159 HydrophobicContact CD2-CD1 4.09Å; L129-E160 HydrophobicContact CD1-CG 4Å
130R97.8Very high98.4Very high168 Ų16859.7 Ų59.763%0.63431%0.312SS*.SBendtrans-133.9-30.9-175.6-69.5173.5-170.2-146.54.7112.6D128 A152D128-R130 WeakPolarHBondContact O-CG 3.35Å; D128-R130 PolarHBondContact O-N 2.81Å; D128-R130 PolarHBondContact OD1-N 3.32Å; R130-A152 WeakPolarHBondContact O-CB 3.27Å
131S98.1Very high98.4Very high40 Ų4055 Ų5528%0.2829%0.294SS..  trans-117.3162.4-177.362.80000111.9N126 D128N126-S131 WeakPolarHBondContact CB-O 3.33Å; N126-S131 WeakPolarHBondContact CB-OG 3.41Å; N126-S131 PolarHBondContact N-O 3.03Å; N126-S131 PolarHBondContact ND2-O 3.21Å; N126-S131 PolarHBondContact ND2-OG 3.38Å; D128-S131 VanDerWaalsContact CG-OG 3.26Å; D128-S131 PolarHBondContact OD1-N 2.84Å; D128-S131 PolarHBondContact OD1-OG 2.83Å; D128-S131 VanDerWaalsContact OD1-OG 3.12Å; D128-S131 PolarHBondContact OD2-OG 3.42Å
132W98.7Very high98.4Very high9 Ų949.8 Ų49.83%0.03427%0.266CS..EExtended strand (participates in β ladder)trans-118.9145.7-177.3-61.895000110.7I123 A124 L125 Q143 W146 E151 A152 W155I123-W132 HydrophobicContact CD1-CB 4.23Å; I123-W132 HydrophobicContact CD1-CD2 4.46Å; I123-W132 HydrophobicContact CD1-CE3 4.25Å; I123-W132 HydrophobicContact CD1-CG 4.48Å; I123-W132 HydrophobicContact CG1-CB 4.34Å; I123-W132 HydrophobicContact CG1-CE3 4.08Å; A124-W132 CarbonylContact O-C 3.54Å; A124-W132 WeakPolarHBondContact O-CA 3.46Å; L125-W132 HydrophobicContact CB-CE3 3.99Å; L125-W132 HydrophobicContact CB-CH2 4.04Å; L125-W132 HydrophobicContact CB-CZ3 3.58Å; L125-W132 HydrophobicContact CD1-CD2 4.16Å; L125-W132 HydrophobicContact CD1-CE3 4.23Å; L125-W132 HydrophobicContact CD1-CH2 3.96Å; L125-W132 HydrophobicContact CD1-CZ2 3.89Å; L125-W132 HydrophobicContact CD1-CZ3 4.11Å; L125-W132 HydrophobicContact CG-CH2 4.47Å; L125-W132 HydrophobicContact CG-CZ3 4.41Å; W132-Q143 HydrophobicContact CB-CG 4.1Å; W132-Q143 PolarHBondContact O-NE2 3.07Å; W132-Q143 VanDerWaalsContact O-NE2 3.14Å; W132-W146 AromaticContact CD2-CE3 3.92Å; W132-W146 HydrophobicContact CD2-CE3 3.92Å; W132-W146 HydrophobicContact CD2-CZ3 4.47Å; W132-W146 AromaticContact CE2-CE3 3.79Å; W132-W146 AromaticContact CE3-CE3 3.78Å; W132-W146 HydrophobicContact CE3-CE3 3.78Å; W132-W146 AromaticContact CE3-CZ3 3.87Å; W132-W146 HydrophobicContact CE3-CZ3 3.87Å; W132-W146 AromaticContact CH2-CE3 3.42Å; W132-W146 HydrophobicContact CH2-CE3 3.42Å; W132-W146 VanDerWaalsContact CH2-CE3 3.42Å; W132-W146 AromaticContact CH2-CZ3 3.45Å; W132-W146 HydrophobicContact CH2-CZ3 3.45Å; W132-W146 VanDerWaalsContact CH2-CZ3 3.45Å; W132-W146 HydrophobicContact CZ2-CD2 4.45Å; W132-W146 AromaticContact CZ2-CE3 3.55Å; W132-W146 HydrophobicContact CZ2-CE3 3.55Å; W132-W146 HydrophobicContact CZ2-CZ3 4.09Å; W132-W146 AromaticContact CZ3-CE3 3.55Å; W132-W146 HydrophobicContact CZ3-CE3 3.55Å; W132-W146 AromaticContact CZ3-CZ3 3.34Å; W132-W146 HydrophobicContact CZ3-CZ3 3.34Å; W132-E151 HydrophobicContact CZ2-CB 4.16Å; W132-A152 HydrophobicContact CZ2-CB 4.26Å; W132-W155 AromaticContact CH2-CD1 3.82Å
133T98.7Very high98.3Very high77 Ų7751.1 Ų51.147%0.47227%0.273SS..EExtended strand (participates in β ladder)trans-108.7116.5167.1-67.10000109I123 A124 N126I123-T133 WeakPolarHBondContact CA-O 3.17Å; A124-T133 PolarHBondContact N-O 2.85Å; A124-T133 PolarHBondContact O-N 2.88Å; N126-T133 PolarHBondContact ND2-OG1 2.89Å; N126-T133 WeakPolarHBondContact OD1-CB 3.3Å; N126-T133 PolarHBondContact OD1-OG1 3.05Å
134A98.7Very high98.3Very high25 Ų2557.8 Ų57.821%0.20730%0.298CS..EExtended strand (participates in β ladder)trans-92.6133.7174.100000110.5A139 Q140 Q143A134-A139 HydrophobicContact CB-CB 3.71Å; A134-Q140 HydrophobicContact CB-CG 3.98Å; A134-Q143 HydrophobicContact CB-CB 4.35Å
135A98.5Very high98.3Very high58 Ų5861.9 Ų61.948%0.47931%0.31SS..SBendtrans-75.2-29.9-177.400000113.4D121 Y122D121-A135 HydrophobicContact CB-CB 4.3Å; D121-A135 WeakPolarHBondContact O-CB 3.14Å; Y122-A135 WeakPolarHBondContact O-CB 3.42Å; Y122-A135 PolarHBondContact O-N 3.08Å
136D98.2Very high98.3Very high60 Ų6063.2 Ų63.232%0.32131%0.314SS..SBendtrans-153.1-174.5-179.567.527.6000113.6Y84 A138 A139 Q140Y84-D136 VanDerWaalsContact CE1-OD2 3.3Å; Y84-D136 WeakPolarHBondContact CE1-OD2 3.33Å; Y84-D136 PolarHBondContact OH-OD1 2.66Å; Y84-D136 PolarHBondContact OH-OD2 2.83Å; D136-A138 VanDerWaalsContact C-N 3.3Å; D136-A138 PolarHBondContact O-N 2.86Å; D136-A138 WeakPolarHBondContact OD1-CA 3.33Å; D136-A138 WeakPolarHBondContact OD1-CB 3.41Å; D136-A138 PolarHBondContact OD1-N 2.85Å; D136-A139 PolarHBondContact O-N 3.01Å; D136-A139 PolarHBondContact OD1-N 2.87Å; D136-Q140 WeakPolarHBondContact O-CG 3.38Å; D136-Q140 PolarHBondContact O-N 2.88Å
137M97.8Very high98.3Very high133 Ų13365.4 Ų65.466%0.65532%0.323SS*.Hα-helixtrans-64.1-30.4-178.9-66.2-58.1-59.200113.7Q140M137-Q140 PolarHBondContact SD-OE1 2.94Å
138A97.6Very high98.3Very high10 Ų1064.4 Ų64.48%0.08333%0.326CS..Hα-helixtrans-74.6-38.9176.400000110.5Y84 Y122 D136 Q140 I141Y84-A138 HydrophobicContact CD1-CB 4.08Å; Y84-A138 HydrophobicContact CE1-CB 3.5Å; Y84-A138 HydrophobicContact CE2-CB 4.04Å; Y84-A138 VanDerWaalsContact CZ-CB 3.49Å; Y122-A138 PolarHBondContact OH-O 2.89Å; D136-A138 VanDerWaalsContact C-N 3.3Å; D136-A138 PolarHBondContact O-N 2.86Å; D136-A138 WeakPolarHBondContact OD1-CA 3.33Å; D136-A138 WeakPolarHBondContact OD1-CB 3.41Å; D136-A138 PolarHBondContact OD1-N 2.85Å; A138-Q140 VanDerWaalsContact C-N 3.31Å; A138-Q140 PolarHBondContact O-N 2.81Å; A138-I141 WeakPolarHBondContact O-CB 3.44Å; A138-I141 PolarHBondContact O-N 3.44Å
139A98.5Very high98.3Very high0 Ų063 Ų630%033%0.326CS..Hα-helixtrans-63-34.2172.800000113Y122 A134 D136 I141 T142 Q143Y122-A139 HydrophobicContact CD2-CB 3.74Å; Y122-A139 VanDerWaalsContact CE2-CA 3.42Å; Y122-A139 HydrophobicContact CE2-CB 3.59Å; Y122-A139 HydrophobicContact CG-CB 4.34Å; Y122-A139 WeakPolarHBondContact O-CB 3.44Å; A134-A139 HydrophobicContact CB-CB 3.71Å; D136-A139 PolarHBondContact O-N 3.01Å; D136-A139 PolarHBondContact OD1-N 2.87Å; A139-I141 PolarHBondContact O-N 3Å; A139-T142 PolarHBondContact O-N 2.88Å; A139-Q143 PolarHBondContact O-N 2.92Å
140Q98.6Very high98.3Very high60 Ų6067.9 Ų67.928%0.2835%0.348SS..Hα-helixtrans-59.8-28174.9-73.5176.61700113.2A134 D136 M137 A138 R144A134-Q140 HydrophobicContact CB-CG 3.98Å; D136-Q140 WeakPolarHBondContact O-CG 3.38Å; D136-Q140 PolarHBondContact O-N 2.88Å; M137-Q140 PolarHBondContact SD-OE1 2.94Å; A138-Q140 VanDerWaalsContact C-N 3.31Å; A138-Q140 PolarHBondContact O-N 2.81Å; Q140-R144 WeakPolarHBondContact O-CG 3.33Å; Q140-R144 PolarHBondContact O-N 2.9Å; Q140-R144 VanDerWaalsContact O-N 3.12Å
141I98.2Very high98.3Very high64 Ų6462.5 Ų62.533%0.32833%0.33SS..Hα-helixtrans-65.1-44.9174.8-57172.2000109.7Y83 A138 A139 K145Y83-I141 HydrophobicContact CD1-CD1 4.23Å; Y83-I141 HydrophobicContact CD2-CD1 4.44Å; Y83-I141 HydrophobicContact CE1-CD1 4.37Å; Y83-I141 HydrophobicContact CE1-CG2 4.17Å; Y83-I141 HydrophobicContact CE2-CB 4.13Å; Y83-I141 HydrophobicContact CE2-CG2 4.04Å; Y83-I141 HydrophobicContact CG-CD1 4.27Å; Y83-I141 WeakPolarHBondContact OH-CG2 3.41Å; A138-I141 WeakPolarHBondContact O-CB 3.44Å; A138-I141 PolarHBondContact O-N 3.44Å; A139-I141 PolarHBondContact O-N 3Å; I141-K145 WeakPolarHBondContact O-CG 3.33Å; I141-K145 PolarHBondContact O-N 2.87Å
142T98.3Very high98.3Very high16 Ų1661 Ų6110%0.09832%0.32CS..Hα-helixtrans-67.9-43177.2-64.80000111.3Y122 I123 A139 R144 K145 W146Y122-T142 HydrophobicContact CE1-CG2 4.2Å; Y122-T142 WeakPolarHBondContact OH-CB 3.41Å; Y122-T142 PolarHBondContact OH-OG1 2.83Å; I123-T142 HydrophobicContact CD1-CG2 4.27Å; A139-T142 PolarHBondContact O-N 2.88Å; T142-R144 PolarHBondContact O-N 3.46Å; T142-K145 WeakPolarHBondContact O-CB 3.46Å; T142-K145 PolarHBondContact O-N 3.26Å; T142-K145 VanDerWaalsContact O-N 3.12Å; T142-W146 HydrophobicContact CG2-CD2 3.88Å; T142-W146 HydrophobicContact CG2-CE3 4.44Å; T142-W146 HydrophobicContact CG2-CG 4.2Å; T142-W146 HydrophobicContact CG2-CZ2 3.94Å; T142-W146 PolarHBondContact O-N 2.89Å
143Q98.7Very high98.3Very high39 Ų3966.8 Ų66.818%0.18235%0.348CS..Hα-helixtrans-51.1-53.5174.8174.8173.317.900111.8I123 W132 A134 A139 K145 W146 E147I123-Q143 HydrophobicContact CD1-CB 3.91Å; W132-Q143 HydrophobicContact CB-CG 4.1Å; W132-Q143 PolarHBondContact O-NE2 3.07Å; W132-Q143 VanDerWaalsContact O-NE2 3.14Å; A134-Q143 HydrophobicContact CB-CB 4.35Å; A139-Q143 PolarHBondContact O-N 2.92Å; Q143-K145 VanDerWaalsContact C-N 3.29Å; Q143-K145 PolarHBondContact O-N 2.82Å; Q143-W146 PolarHBondContact O-N 2.83Å; Q143-W146 VanDerWaalsContact O-N 3.16Å; Q143-E147 HydrophobicContact CG-CG 4.31Å; Q143-E147 VanDerWaalsContact CG-OE1 3.23Å; Q143-E147 WeakPolarHBondContact CG-OE1 3.37Å; Q143-E147 PolarHBondContact NE2-OE1 3.49Å; Q143-E147 WeakPolarHBondContact O-CB 3.44Å; Q143-E147 WeakPolarHBondContact O-CG 3.31Å; Q143-E147 PolarHBondContact O-N 2.98Å
144R98.6Very high98.2Very high143 Ų14368.9 Ų68.954%0.5435%0.352SS..Hα-helixtrans-60.8-37.8-179.5-67.8172.1-161.7151.69.1112.6Q140 T142 T148Q140-R144 WeakPolarHBondContact O-CG 3.33Å; Q140-R144 PolarHBondContact O-N 2.9Å; Q140-R144 VanDerWaalsContact O-N 3.12Å; T142-R144 PolarHBondContact O-N 3.46Å; R144-T148 WeakPolarHBondContact O-CB 3.15Å; R144-T148 PolarHBondContact O-N 3.01Å; R144-T148 PolarHBondContact O-OG1 3.46Å
145K98.1Very high98.2Very high117 Ų11769.4 Ų69.451%0.50935%0.349SS..Hα-helixtrans-64.2-46.6175.9-73.4177.1174.5-1750111.1Y83 I141 T142 Q143 T148 A149Y83-K145 PolarHBondContact OH-NZ 2.82Å; I141-K145 WeakPolarHBondContact O-CG 3.33Å; I141-K145 PolarHBondContact O-N 2.87Å; T142-K145 WeakPolarHBondContact O-CB 3.46Å; T142-K145 PolarHBondContact O-N 3.26Å; T142-K145 VanDerWaalsContact O-N 3.12Å; Q143-K145 VanDerWaalsContact C-N 3.29Å; Q143-K145 PolarHBondContact O-N 2.82Å; K145-T148 PolarHBondContact O-N 3.15Å; K145-A149 WeakPolarHBondContact O-CB 2.87Å; K145-A149 PolarHBondContact O-N 2.8Å
146W98.3Very high98.2Very high44 Ų4470.4 Ų70.417%0.16734%0.34CS..Hα-helixtrans-69-36.8-179.1-74.57.4000112.8I123 W132 T142 Q143 A149 H150 E151I123-W146 HydrophobicContact CD1-CE3 4.01Å; I123-W146 HydrophobicContact CD1-CZ3 4.25Å; I123-W146 HydrophobicContact CG2-CH2 3.96Å; I123-W146 HydrophobicContact CG2-CZ3 3.73Å; W132-W146 AromaticContact CD2-CE3 3.92Å; W132-W146 HydrophobicContact CD2-CE3 3.92Å; W132-W146 HydrophobicContact CD2-CZ3 4.47Å; W132-W146 AromaticContact CE2-CE3 3.79Å; W132-W146 AromaticContact CE3-CE3 3.78Å; W132-W146 HydrophobicContact CE3-CE3 3.78Å; W132-W146 AromaticContact CE3-CZ3 3.87Å; W132-W146 HydrophobicContact CE3-CZ3 3.87Å; W132-W146 AromaticContact CH2-CE3 3.42Å; W132-W146 HydrophobicContact CH2-CE3 3.42Å; W132-W146 VanDerWaalsContact CH2-CE3 3.42Å; W132-W146 AromaticContact CH2-CZ3 3.45Å; W132-W146 HydrophobicContact CH2-CZ3 3.45Å; W132-W146 VanDerWaalsContact CH2-CZ3 3.45Å; W132-W146 HydrophobicContact CZ2-CD2 4.45Å; W132-W146 AromaticContact CZ2-CE3 3.55Å; W132-W146 HydrophobicContact CZ2-CE3 3.55Å; W132-W146 HydrophobicContact CZ2-CZ3 4.09Å; W132-W146 AromaticContact CZ3-CE3 3.55Å; W132-W146 HydrophobicContact CZ3-CE3 3.55Å; W132-W146 AromaticContact CZ3-CZ3 3.34Å; W132-W146 HydrophobicContact CZ3-CZ3 3.34Å; T142-W146 HydrophobicContact CG2-CD2 3.88Å; T142-W146 HydrophobicContact CG2-CE3 4.44Å; T142-W146 HydrophobicContact CG2-CG 4.2Å; T142-W146 HydrophobicContact CG2-CZ2 3.94Å; T142-W146 PolarHBondContact O-N 2.89Å; Q143-W146 PolarHBondContact O-N 2.83Å; Q143-W146 VanDerWaalsContact O-N 3.16Å; W146-A149 CarbonylContact O-C 3.55Å; W146-A149 PolarHBondContact O-N 2.79Å; W146-H150 PolarHBondContact O-N 3Å; W146-E151 HydrophobicContact CB-CB 3.94Å; W146-E151 HydrophobicContact CB-CG 3.89Å; W146-E151 HydrophobicContact CG-CB 4.18Å; W146-E151 HydrophobicContact CG-CG 3.87Å; W146-E151 PolarHBondContact O-N 2.95Å
147E98.4Very high98.2Very high88 Ų8870.8 Ų70.841%0.41135%0.352SS..Hα-helixtrans-63.7-45172.4-73.4169.7173.500111.2Q143 A149 H150Q143-E147 HydrophobicContact CG-CG 4.31Å; Q143-E147 VanDerWaalsContact CG-OE1 3.23Å; Q143-E147 WeakPolarHBondContact CG-OE1 3.37Å; Q143-E147 PolarHBondContact NE2-OE1 3.49Å; Q143-E147 WeakPolarHBondContact O-CB 3.44Å; Q143-E147 WeakPolarHBondContact O-CG 3.31Å; Q143-E147 PolarHBondContact O-N 2.98Å; E147-A149 VanDerWaalsContact C-N 3.27Å; E147-A149 PolarHBondContact O-N 2.88Å; E147-H150 PolarHBondContact O-N 3.25Å; E147-H150 VanDerWaalsContact O-N 3.16Å
148T98.3Very high98.2Very high115 Ų11566.1 Ų66.171%0.70633%0.327SS*.Hα-helixtrans-63.3-34.4176.4-56.20000112.1R144 K145 H150R144-T148 WeakPolarHBondContact O-CB 3.15Å; R144-T148 PolarHBondContact O-N 3.01Å; R144-T148 PolarHBondContact O-OG1 3.46Å; K145-T148 PolarHBondContact O-N 3.15Å; T148-H150 VanDerWaalsContact C-N 3.33Å
149A98Very high98.3Very high51 Ų5165.6 Ų65.642%0.42132%0.323SS..THydrogen-bonded Turntrans-87.31.4178.900000113.8K145 W146 E147 E151K145-A149 WeakPolarHBondContact O-CB 2.87Å; K145-A149 PolarHBondContact O-N 2.8Å; W146-A149 CarbonylContact O-C 3.55Å; W146-A149 PolarHBondContact O-N 2.79Å; E147-A149 VanDerWaalsContact C-N 3.27Å; E147-A149 PolarHBondContact O-N 2.88Å; A149-E151 HydrophobicContact CB-CG 4.02Å; A149-E151 PolarHBondContact O-N 3.26Å
150H97.6Very high98.3Very high109 Ų10969.3 Ų69.351%0.50534%0.34SS..THydrogen-bonded Turntrans53.735.5-177.2-59.9-85.9000113.6W146 E147 T148 A152 E153W146-H150 PolarHBondContact O-N 3Å; E147-H150 PolarHBondContact O-N 3.25Å; E147-H150 VanDerWaalsContact O-N 3.16Å; T148-H150 VanDerWaalsContact C-N 3.33Å; H150-A152 PolarHBondContact O-N 3.22Å; H150-E153 HydrophobicContact CB-CG 4.39Å; H150-E153 IonicContact CG-OE1 3.34Å; H150-E153 IonicContact ND1-OE1 3.48Å; H150-E153 PolarHBondContact ND1-OE1 3.11Å; H150-E153 WeakPolarHBondContact O-CB 3.48Å; H150-E153 PolarHBondContact O-N 3.09Å; H150-E153 VanDerWaalsContact O-N 3.08Å
151E98Very high98.3Very high54 Ų5467.6 Ų67.625%0.25234%0.338SS..Hα-helixtrans-59.5-32.7-176.5-71.5-74.6176.200112.6W132 W146 A149 E153 Q154 W155W132-E151 HydrophobicContact CZ2-CB 4.16Å; W146-E151 HydrophobicContact CB-CB 3.94Å; W146-E151 HydrophobicContact CB-CG 3.89Å; W146-E151 HydrophobicContact CG-CB 4.18Å; W146-E151 HydrophobicContact CG-CG 3.87Å; W146-E151 PolarHBondContact O-N 2.95Å; A149-E151 HydrophobicContact CB-CG 4.02Å; A149-E151 PolarHBondContact O-N 3.26Å; E151-E153 PolarHBondContact O-N 3.16Å; E151-Q154 PolarHBondContact O-N 3.15Å; E151-W155 PolarHBondContact O-N 3.14Å
152A98.4Very high98.3Very high9 Ų971.7 Ų71.77%0.07435%0.35CS..Hα-helixtrans-59.8-34.8177.900000112.2L125 R130 W132 H150 W155 R156L125-A152 HydrophobicContact CD1-CB 3.99Å; R130-A152 WeakPolarHBondContact O-CB 3.27Å; W132-A152 HydrophobicContact CZ2-CB 4.26Å; H150-A152 PolarHBondContact O-N 3.22Å; A152-W155 PolarHBondContact O-N 3.27Å; A152-R156 VanDerWaalsContact O-CB 3.24Å; A152-R156 WeakPolarHBondContact O-CB 3.25Å; A152-R156 PolarHBondContact O-N 3.18Å
153E98.1Very high98.3Very high131 Ų13170.9 Ų70.961%0.61235%0.345SS*.Hα-helixtrans-67.9-39179-62.4178.6-166.100111.6H150 E151 R156 A157H150-E153 HydrophobicContact CB-CG 4.39Å; H150-E153 IonicContact CG-OE1 3.34Å; H150-E153 IonicContact ND1-OE1 3.48Å; H150-E153 PolarHBondContact ND1-OE1 3.11Å; H150-E153 WeakPolarHBondContact O-CB 3.48Å; H150-E153 PolarHBondContact O-N 3.09Å; H150-E153 VanDerWaalsContact O-N 3.08Å; E151-E153 PolarHBondContact O-N 3.16Å; E153-R156 PolarHBondContact O-N 3.22Å; E153-A157 WeakPolarHBondContact O-CB 3.05Å; E153-A157 PolarHBondContact O-N 3.12Å
154Q97.7Very high98.3Very high121 Ų12169.4 Ų69.457%0.56534%0.338SS*.Hα-helixtrans-66.3-44.4176.3-59-173.731.700111.3E151 A157 Y158E151-Q154 PolarHBondContact O-N 3.15Å; Q154-A157 PolarHBondContact O-N 3.14Å; Q154-Y158 PolarHBondContact O-N 2.97Å
155W98.4Very high98.3Very high35 Ų3568.4 Ų68.413%0.13334%0.34CS..Hα-helixtrans-62.9-46.2175.6-82.1110.5000111.7Y98 Q113 L125 W132 E151 A152 A157 Y158 L159Y98-W155 HydrophobicContact CD1-CH2 4.16Å; Y98-W155 HydrophobicContact CD1-CZ3 4.43Å; Y98-W155 HydrophobicContact CD2-CH2 4.41Å; Y98-W155 AromaticContact CD2-CZ3 3.9Å; Y98-W155 HydrophobicContact CD2-CZ3 3.9Å; Y98-W155 HydrophobicContact CG-CH2 4.02Å; Y98-W155 AromaticContact CG-CZ3 3.84Å; Y98-W155 HydrophobicContact CG-CZ3 3.84Å; Q113-W155 HydrophobicContact CB-CD2 4.23Å; Q113-W155 HydrophobicContact CB-CE3 4.3Å; Q113-W155 HydrophobicContact CG-CD2 3.65Å; Q113-W155 VanDerWaalsContact CG-CE2 3.5Å; Q113-W155 HydrophobicContact CG-CE3 3.9Å; Q113-W155 HydrophobicContact CG-CG 4.25Å; Q113-W155 HydrophobicContact CG-CH2 3.88Å; Q113-W155 HydrophobicContact CG-CZ2 3.63Å; Q113-W155 HydrophobicContact CG-CZ3 4.01Å; L125-W155 HydrophobicContact CD2-CB 3.92Å; W132-W155 AromaticContact CH2-CD1 3.82Å; E151-W155 PolarHBondContact O-N 3.14Å; A152-W155 PolarHBondContact O-N 3.27Å; W155-A157 VanDerWaalsContact C-N 3.35Å; W155-A157 PolarHBondContact O-N 3.04Å; W155-Y158 HydrophobicContact CE3-CD1 4.2Å; W155-Y158 HydrophobicContact CZ3-CD1 4.13Å; W155-Y158 HydrophobicContact CZ3-CE1 4.48Å; W155-Y158 PolarHBondContact O-N 3.33Å; W155-Y158 VanDerWaalsContact O-N 3.16Å; W155-L159 HydrophobicContact CB-CD1 4.41Å; W155-L159 WeakPolarHBondContact O-CB 3.49Å; W155-L159 WeakPolarHBondContact O-CG 3.4Å; W155-L159 PolarHBondContact O-N 2.98Å
156R98.6Very high98.3Very high79 Ų7965.2 Ų65.230%0.29833%0.325SS..Hα-helixtrans-56.9-47.6176.1-175.3173.9178.7-145.4-13.4111.9L129 A152 E153 Y158 L159 E160L129-R156 HydrophobicContact CB-CB 4.05Å; L129-R156 HydrophobicContact CB-CG 3.92Å; L129-R156 HydrophobicContact CD1-CG 4.1Å; A152-R156 VanDerWaalsContact O-CB 3.24Å; A152-R156 WeakPolarHBondContact O-CB 3.25Å; A152-R156 PolarHBondContact O-N 3.18Å; E153-R156 PolarHBondContact O-N 3.22Å; R156-Y158 VanDerWaalsContact C-N 3.3Å; R156-Y158 PolarHBondContact O-N 2.99Å; R156-L159 PolarHBondContact O-N 3.3Å; R156-E160 HydrophobicContact CG-CG 4.15Å; R156-E160 IonicContact CZ-OE1 3.52Å; R156-E160 IonicContact CZ-OE2 3.87Å; R156-E160 IonicContact NE-OE1 2.82Å; R156-E160 PolarHBondContact NE-OE1 2.87Å; R156-E160 IonicContact NE-OE2 3.03Å; R156-E160 PolarHBondContact NE-OE2 3.16Å; R156-E160 IonicContact NH2-OE1 3.05Å; R156-E160 PolarHBondContact NH2-OE1 3.17Å; R156-E160 IonicContact NH2-OE2 3.92Å; R156-E160 PolarHBondContact NH2-OE2 3.05Å; R156-E160 WeakPolarHBondContact O-CB 3.39Å; R156-E160 PolarHBondContact O-N 3.29Å
157A98.4Very high98.3Very high68 Ų6863.1 Ų63.156%0.56232%0.317SS*.Hα-helixtrans-61.2-37.5177.800000112.7E153 Q154 W155 G161E153-A157 WeakPolarHBondContact O-CB 3.05Å; E153-A157 PolarHBondContact O-N 3.12Å; Q154-A157 PolarHBondContact O-N 3.14Å; W155-A157 VanDerWaalsContact C-N 3.35Å; W155-A157 PolarHBondContact O-N 3.04Å; A157-G161 PolarHBondContact O-N 2.8Å
158Y98.4Very high98.3Very high35 Ų3564.7 Ų64.714%0.13732%0.319CS..Iπ-helixtrans-68.8-47.9173.8171.9-100.4000112.3Y98 Q154 W155 R156 G161 R162 C163Y98-Y158 AromaticContact CD2-CE1 3.82Å; Y98-Y158 HydrophobicContact CD2-CE1 3.82Å; Y98-Y158 AromaticContact CE2-CE1 3.72Å; Y98-Y158 HydrophobicContact CE2-CE1 3.72Å; Y98-Y158 AromaticContact CE2-CZ 3.96Å; Q154-Y158 PolarHBondContact O-N 2.97Å; W155-Y158 HydrophobicContact CE3-CD1 4.2Å; W155-Y158 HydrophobicContact CZ3-CD1 4.13Å; W155-Y158 HydrophobicContact CZ3-CE1 4.48Å; W155-Y158 PolarHBondContact O-N 3.33Å; W155-Y158 VanDerWaalsContact O-N 3.16Å; R156-Y158 VanDerWaalsContact C-N 3.3Å; R156-Y158 PolarHBondContact O-N 2.99Å; Y158-G161 CarbonylContact O-C 3.55Å; Y158-R162 HydrophobicContact CD2-CB 3.88Å; Y158-R162 HydrophobicContact CE2-CB 4.12Å; Y158-R162 PolarHBondContact O-N 3.19Å; Y158-R162 VanDerWaalsContact O-N 3.12Å; Y158-C163 HydrophobicContact CD1-CB 4.35Å; Y158-C163 HydrophobicContact CE1-CB 3.93Å; Y158-C163 WeakPolarHBondContact O-CB 3.4Å; Y158-C163 PolarHBondContact O-N 2.93Å
159L98.8Very high98.3Very high0 Ų065.1 Ų65.10%031%0.308CS..Iπ-helixtrans-70.6-44.1-172.3-69.1171.8000112.4G99 F108 L125 L129 W155 R156G99-L159 WeakPolarHBondContact O-CD2 3.4Å; F108-L159 HydrophobicContact CE2-CB 4.48Å; F108-L159 WeakPolarHBondContact CE2-O 3.49Å; L125-L159 HydrophobicContact CD2-CD1 3.9Å; L129-L159 HydrophobicContact CD2-CD1 4.09Å; W155-L159 HydrophobicContact CB-CD1 4.41Å; W155-L159 WeakPolarHBondContact O-CB 3.49Å; W155-L159 WeakPolarHBondContact O-CG 3.4Å; W155-L159 PolarHBondContact O-N 2.98Å; R156-L159 PolarHBondContact O-N 3.3Å
160E98.4Very high98.3Very high78 Ų7862.8 Ų62.836%0.36429%0.288SS..Iπ-helixtrans-76.2-25.2178.1-67.1-178.5178.300112.4F108 L129 R156F108-E160 HydrophobicContact CD1-CG 4.15Å; F108-E160 HydrophobicContact CE1-CG 3.94Å; F108-E160 HydrophobicContact CE2-CG 4.39Å; F108-E160 HydrophobicContact CG-CG 4.46Å; F108-E160 HydrophobicContact CZ-CG 4.07Å; L129-E160 HydrophobicContact CD1-CG 4Å; R156-E160 HydrophobicContact CG-CG 4.15Å; R156-E160 IonicContact CZ-OE1 3.52Å; R156-E160 IonicContact CZ-OE2 3.87Å; R156-E160 IonicContact NE-OE1 2.82Å; R156-E160 PolarHBondContact NE-OE1 2.87Å; R156-E160 IonicContact NE-OE2 3.03Å; R156-E160 PolarHBondContact NE-OE2 3.16Å; R156-E160 IonicContact NH2-OE1 3.05Å; R156-E160 PolarHBondContact NH2-OE1 3.17Å; R156-E160 IonicContact NH2-OE2 3.92Å; R156-E160 PolarHBondContact NH2-OE2 3.05Å; R156-E160 WeakPolarHBondContact O-CB 3.39Å; R156-E160 PolarHBondContact O-N 3.29Å
161G98.3Very high98.3Very high23 Ų2358.2 Ų58.224%0.23727%0.267CS..Iπ-helixtrans-106.4-93.4-176.900000113.2A157 Y158 C163 V164 E165A157-G161 PolarHBondContact O-N 2.8Å; Y158-G161 CarbonylContact O-C 3.55Å; G161-C163 VanDerWaalsContact C-N 3.28Å; G161-C163 PolarHBondContact O-N 3.36Å; G161-V164 PolarHBondContact O-N 2.82Å; G161-E165 WeakPolarHBondContact O-CG 3.2Å; G161-E165 PolarHBondContact O-N 2.87Å
162R98Very high98.2Very high150 Ų15061.8 Ų61.857%0.56628%0.284SS*.Iπ-helixtrans-55.8-38.6-170.1-70.8-171.1-67.8169.20.5113.5Y158 E165 W166Y158-R162 HydrophobicContact CD2-CB 3.88Å; Y158-R162 HydrophobicContact CE2-CB 4.12Å; Y158-R162 PolarHBondContact O-N 3.19Å; Y158-R162 VanDerWaalsContact O-N 3.12Å; R162-E165 PolarHBondContact O-N 3.24Å; R162-W166 PolarHBondContact O-N 2.8Å
163C98.6Very high98.2Very high0 Ų063.6 Ų63.60%029%0.292CS..Iπ-helixtrans-60.5-48178.7-175.30000111M4 C100 Y158 G161 W166 L167M4-C163 HydrophobicContact CE-CB 4.16Å; M4-C163 VanDerWaalsContact CE-O 3.23Å; M4-C163 WeakPolarHBondContact CE-O 3.3Å; M4-C163 WeakPolarHBondContact CE-SG 3.44Å; C100-C163 HydrophobicContact CB-CB 3.88Å; C100-C163 WeakPolarHBondContact CB-SG 3.3Å; C100-C163 PolarHBondContact N-SG 3.26Å; C100-C163 WeakPolarHBondContact SG-CB 3.44Å; C100-C163 CovalentContact SG-SG 2.04Å; C100-C163 PolarHBondContact SG-SG 3.49Å; Y158-C163 HydrophobicContact CD1-CB 4.35Å; Y158-C163 HydrophobicContact CE1-CB 3.93Å; Y158-C163 WeakPolarHBondContact O-CB 3.4Å; Y158-C163 PolarHBondContact O-N 2.93Å; G161-C163 VanDerWaalsContact C-N 3.28Å; G161-C163 PolarHBondContact O-N 3.36Å; C163-W166 PolarHBondContact O-N 3.06Å; C163-L167 WeakPolarHBondContact O-CB 3.03Å; C163-L167 PolarHBondContact O-N 3.45Å
164V98.7Very high98.1Very high7 Ų757.5 Ų57.54%0.04226%0.264CS..Hα-helixtrans-64.4-42.2178.1174.30000111.3V102 F108 G161 L167 R168V102-V164 HydrophobicContact CG1-CB 4.39Å; V102-V164 HydrophobicContact CG1-CG1 3.9Å; V102-V164 HydrophobicContact CG1-CG2 4.03Å; F108-V164 HydrophobicContact CB-CG2 4.02Å; F108-V164 HydrophobicContact CD2-CG2 3.67Å; F108-V164 HydrophobicContact CG-CG2 4.33Å; G161-V164 PolarHBondContact O-N 2.82Å; V164-L167 PolarHBondContact O-N 2.63Å; V164-R168 WeakPolarHBondContact O-CG 3.24Å; V164-R168 PolarHBondContact O-N 3.14Å
165E98.4Very high98Very high123 Ų12357 Ų5758%0.57526%0.26SS*.Hα-helixtrans-59.3-47.3176.8-69.9173173.800111.9G161 R162 R169G161-E165 WeakPolarHBondContact O-CG 3.2Å; G161-E165 PolarHBondContact O-N 2.87Å; R162-E165 PolarHBondContact O-N 3.24Å; E165-R169 PolarHBondContact O-N 3.06Å; E165-R169 VanDerWaalsContact O-N 3.1Å
166W98.3Very high97.7Very high50 Ų5063.7 Ų63.719%0.18929%0.293CS..Hα-helixtrans-66.1-43.7177.3-81.1110000112.1M4 Y58 R162 C163 R168 R169 Y170M4-W166 HydrophobicContact CE-CB 4.01Å; M4-W166 HydrophobicContact SD-CB 4.32Å; Y58-W166 AromaticContact CD2-CH2 3.68Å; Y58-W166 HydrophobicContact CD2-CH2 3.68Å; Y58-W166 HydrophobicContact CD2-CZ2 4.38Å; Y58-W166 AromaticContact CD2-CZ3 3.83Å; Y58-W166 HydrophobicContact CD2-CZ3 3.83Å; Y58-W166 HydrophobicContact CE2-CE3 4.23Å; Y58-W166 HydrophobicContact CE2-CH2 4.02Å; Y58-W166 AromaticContact CE2-CZ3 3.8Å; Y58-W166 HydrophobicContact CE2-CZ3 3.8Å; R162-W166 PolarHBondContact O-N 2.8Å; C163-W166 PolarHBondContact O-N 3.06Å; W166-R168 VanDerWaalsContact C-N 3.34Å; W166-R168 PolarHBondContact O-N 3.45Å; W166-R169 PolarHBondContact O-N 2.87Å; W166-Y170 HydrophobicContact CB-CE2 4.02Å; W166-Y170 HydrophobicContact CE3-CD1 4.42Å; W166-Y170 AromaticContact CE3-CE1 3.47Å; W166-Y170 HydrophobicContact CE3-CE1 3.47Å; W166-Y170 VanDerWaalsContact CE3-CE1 3.47Å; W166-Y170 HydrophobicContact CE3-CE2 4.35Å; W166-Y170 AromaticContact CE3-CZ 3.43Å; W166-Y170 VanDerWaalsContact CE3-CZ 3.43Å; W166-Y170 AromaticContact CZ3-CE1 3.93Å; W166-Y170 HydrophobicContact CZ3-CE1 3.93Å; W166-Y170 WeakPolarHBondContact O-CD2 3.32Å; W166-Y170 PolarHBondContact O-N 2.83Å
167L98.6Very high97.5Very high0 Ų062.1 Ų62.10%029%0.292CS..Hα-helixtrans-58.9-45.7177.5175.152.4000111.3H2 M4 V27 V102 C163 V164 R169 Y170 L171H2-L167 HydrophobicContact CB-CD1 4.4Å; M4-L167 HydrophobicContact CB-CB 4.07Å; M4-L167 HydrophobicContact CB-CD1 4.01Å; M4-L167 HydrophobicContact CB-CD2 4.16Å; M4-L167 HydrophobicContact CB-CG 4.3Å; V27-L167 HydrophobicContact CG1-CD1 3.63Å; V27-L167 HydrophobicContact CG2-CD1 4.3Å; V102-L167 HydrophobicContact CB-CD2 4.34Å; V102-L167 HydrophobicContact CG1-CD2 3.93Å; V102-L167 HydrophobicContact CG2-CD2 3.63Å; V102-L167 HydrophobicContact CG2-CG 4.18Å; C163-L167 WeakPolarHBondContact O-CB 3.03Å; C163-L167 PolarHBondContact O-N 3.45Å; V164-L167 PolarHBondContact O-N 2.63Å; L167-R169 PolarHBondContact O-N 3.39Å; L167-Y170 PolarHBondContact O-N 2.68Å; L167-L171 HydrophobicContact CD1-CD1 3.84Å; L167-L171 HydrophobicContact CD1-CD2 4.45Å; L167-L171 HydrophobicContact CD1-CG 3.89Å; L167-L171 HydrophobicContact CG-CD1 3.99Å; L167-L171 HydrophobicContact CG-CG 4.49Å; L167-L171 WeakPolarHBondContact O-CB 3.36Å; L167-L171 VanDerWaalsContact O-CG 3.29Å; L167-L171 WeakPolarHBondContact O-CG 3.49Å; L167-L171 PolarHBondContact O-N 3.19Å
168R98.1Very high97.2Very high120 Ų12059 Ų5945%0.45327%0.266SS..Hα-helixtrans-59.8-44.3175.5-72.6175.2-177.9175.71.2112.3G106 V164 W166 Y170 L171 E172G106-R168 PolarHBondContact O-NE 3.44Å; G106-R168 PolarHBondContact O-NH2 2.89Å; V164-R168 WeakPolarHBondContact O-CG 3.24Å; V164-R168 PolarHBondContact O-N 3.14Å; W166-R168 VanDerWaalsContact C-N 3.34Å; W166-R168 PolarHBondContact O-N 3.45Å; R168-Y170 VanDerWaalsContact C-N 3.35Å; R168-Y170 PolarHBondContact O-N 3.01Å; R168-L171 PolarHBondContact O-N 3.07Å; R168-E172 PolarHBondContact O-N 3.26Å
169R97.7Very high97Very high125 Ų12561.4 Ų61.447%0.47228%0.279SS..Hα-helixtrans-61.1-43.4176.4179.3176.9172.8110.6-5.8111.5E54 E165 W166 L167 E172 N173E54-R169 IonicContact OE1-CZ 2.81Å; E54-R169 IonicContact OE1-NE 4Å; E54-R169 PolarHBondContact OE1-NE 2.91Å; E54-R169 IonicContact OE1-NH2 3.39Å; E54-R169 PolarHBondContact OE1-NH2 2.89Å; E54-R169 IonicContact OE2-CZ 3.61Å; E54-R169 IonicContact OE2-NE 3.41Å; E54-R169 PolarHBondContact OE2-NE 2.89Å; E54-R169 IonicContact OE2-NH2 3.05Å; E54-R169 PolarHBondContact OE2-NH2 2.79Å; E165-R169 PolarHBondContact O-N 3.06Å; E165-R169 VanDerWaalsContact O-N 3.1Å; W166-R169 PolarHBondContact O-N 2.87Å; L167-R169 PolarHBondContact O-N 3.39Å; R169-E172 PolarHBondContact O-N 3.11Å; R169-N173 WeakPolarHBondContact O-CB 3.33Å; R169-N173 PolarHBondContact O-N 3.39Å; R169-N173 PolarHBondContact O-OD1 3.43Å
170Y98.1Very high96.8Very high1 Ų165.1 Ų65.10%0.00429%0.293CS..Hα-helixtrans-67.6-38.9178.7-61.6-25.7000112.7M4 V27 F32 W50 I51 Y58 W166 L167 R168 E172 N173 G174 L178M4-Y170 HydrophobicContact SD-CD2 3.79Å; M4-Y170 HydrophobicContact SD-CE2 3.57Å; M4-Y170 VanDerWaalsContact SD-CE2 3.57Å; V27-Y170 HydrophobicContact CG2-CD2 3.93Å; V27-Y170 HydrophobicContact CG2-CG 4.45Å; F32-Y170 HydrophobicContact CD2-CE2 4.43Å; F32-Y170 HydrophobicContact CE2-CD2 4.21Å; F32-Y170 AromaticContact CE2-CE2 3.62Å; F32-Y170 HydrophobicContact CE2-CE2 3.62Å; F32-Y170 AromaticContact CE2-CZ 3.99Å; F32-Y170 HydrophobicContact CZ-CD2 4.27Å; F32-Y170 AromaticContact CZ-CE2 3.78Å; F32-Y170 HydrophobicContact CZ-CE2 3.78Å; W50-Y170 HydrophobicContact CH2-CG 4.3Å; W50-Y170 AromaticContact CZ3-CD1 3.88Å; W50-Y170 HydrophobicContact CZ3-CD1 3.88Å; W50-Y170 HydrophobicContact CZ3-CD2 4.41Å; W50-Y170 AromaticContact CZ3-CG 3.74Å; W50-Y170 HydrophobicContact CZ3-CG 3.74Å; I51-Y170 HydrophobicContact CD1-CD1 3.8Å; I51-Y170 HydrophobicContact CD1-CE1 3.32Å; Y58-Y170 WeakPolarHBondContact CE2-OH 3.44Å; Y58-Y170 VanDerWaalsContact CZ-OH 3.26Å; Y58-Y170 PolarHBondContact OH-OH 3.03Å; W166-Y170 HydrophobicContact CB-CE2 4.02Å; W166-Y170 HydrophobicContact CE3-CD1 4.42Å; W166-Y170 AromaticContact CE3-CE1 3.47Å; W166-Y170 HydrophobicContact CE3-CE1 3.47Å; W166-Y170 VanDerWaalsContact CE3-CE1 3.47Å; W166-Y170 HydrophobicContact CE3-CE2 4.35Å; W166-Y170 AromaticContact CE3-CZ 3.43Å; W166-Y170 VanDerWaalsContact CE3-CZ 3.43Å; W166-Y170 AromaticContact CZ3-CE1 3.93Å; W166-Y170 HydrophobicContact CZ3-CE1 3.93Å; W166-Y170 WeakPolarHBondContact O-CD2 3.32Å; W166-Y170 PolarHBondContact O-N 2.83Å; L167-Y170 PolarHBondContact O-N 2.68Å; R168-Y170 VanDerWaalsContact C-N 3.35Å; R168-Y170 PolarHBondContact O-N 3.01Å; Y170-E172 VanDerWaalsContact C-N 3.28Å; Y170-E172 PolarHBondContact O-N 3.29Å; Y170-N173 PolarHBondContact O-N 2.86Å; Y170-G174 PolarHBondContact O-N 3.1Å; Y170-L178 WeakPolarHBondContact O-CD1 3.36Å
171L97.6Very high96.6Very high14 Ų1464.3 Ų64.37%0.07329%0.293CS..Hα-helixtrans-63.8-34174.7-71.5168.4000112.6H2 V27 V102 L167 R168 K175 L178 Q179H2-L171 HydrophobicContact CB-CD1 3.68Å; H2-L171 HydrophobicContact CB-CD2 3.99Å; H2-L171 HydrophobicContact CB-CG 4.41Å; H2-L171 WeakPolarHBondContact ND1-CD2 3.28Å; V27-L171 HydrophobicContact CG1-CD2 4.07Å; V102-L171 HydrophobicContact CG2-CD1 4.48Å; L167-L171 HydrophobicContact CD1-CD1 3.84Å; L167-L171 HydrophobicContact CD1-CD2 4.45Å; L167-L171 HydrophobicContact CD1-CG 3.89Å; L167-L171 HydrophobicContact CG-CD1 3.99Å; L167-L171 HydrophobicContact CG-CG 4.49Å; L167-L171 WeakPolarHBondContact O-CB 3.36Å; L167-L171 VanDerWaalsContact O-CG 3.29Å; L167-L171 WeakPolarHBondContact O-CG 3.49Å; L167-L171 PolarHBondContact O-N 3.19Å; R168-L171 PolarHBondContact O-N 3.07Å; L171-K175 WeakPolarHBondContact O-CA 3.34Å; L171-K175 WeakPolarHBondContact O-CB 3.48Å; L171-K175 PolarHBondContact O-N 2.86Å; L171-K175 VanDerWaalsContact O-N 3.14Å; L171-L178 HydrophobicContact CD2-CB 4.14Å; L171-L178 HydrophobicContact CD2-CD1 4.32Å; L171-Q179 PolarHBondContact O-NE2 2.71Å
172E97.1Very high96.6Very high128 Ų12865.8 Ų65.860%0.59830%0.296SS*.Hα-helixtrans-72.5-49.2173.8-171.859.5-150.800111R168 R169 Y170 G174 K175R168-E172 PolarHBondContact O-N 3.26Å; R169-E172 PolarHBondContact O-N 3.11Å; Y170-E172 VanDerWaalsContact C-N 3.28Å; Y170-E172 PolarHBondContact O-N 3.29Å; E172-G174 VanDerWaalsContact C-N 3.31Å; E172-G174 PolarHBondContact O-N 3.37Å; E172-K175 WeakPolarHBondContact O-CB 3.37Å; E172-K175 PolarHBondContact O-N 3.41Å
173N97.3Very high96.6Very high47 Ų4761 Ų6125%0.25129%0.288SS..Hα-helixtrans-58.7-42179.1-70.6-2.9000112.7Q53 E54 R169 Y170Q53-N173 PolarHBondContact NE2-ND2 3.38Å; Q53-N173 PolarHBondContact NE2-OD1 3.22Å; Q53-N173 VanDerWaalsContact NE2-OD1 3.11Å; E54-N173 PolarHBondContact OE1-ND2 3.44Å; R169-N173 WeakPolarHBondContact O-CB 3.33Å; R169-N173 PolarHBondContact O-N 3.39Å; R169-N173 PolarHBondContact O-OD1 3.43Å; Y170-N173 PolarHBondContact O-N 2.86Å
174G96.5Very high96.5Very high3 Ų361.4 Ų61.43%0.03129%0.29CS..THydrogen-bonded Turntrans-102.319.4-17600000113.6W50 Y170 E172 E176 T177 L178W50-G174 VanDerWaalsContact CG-CA 3.49Å; Y170-G174 PolarHBondContact O-N 3.1Å; E172-G174 VanDerWaalsContact C-N 3.31Å; E172-G174 PolarHBondContact O-N 3.37Å; G174-E176 VanDerWaalsContact C-N 3.28Å; G174-E176 PolarHBondContact O-N 3.31Å; G174-E176 VanDerWaalsContact O-N 3.15Å; G174-T177 PolarHBondContact O-N 2.81Å; G174-L178 WeakPolarHBondContact O-CB 3.47Å; G174-L178 PolarHBondContact O-N 2.93Å
175K95.3Very high96.5Very high110 Ų11067.9 Ų67.948%0.47832%0.318SS..Hα-helixtrans-48.5-45.9-171.2-177.2174.1-176.1174.40114L171 E172 T177 Q179L171-K175 WeakPolarHBondContact O-CA 3.34Å; L171-K175 WeakPolarHBondContact O-CB 3.48Å; L171-K175 PolarHBondContact O-N 2.86Å; L171-K175 VanDerWaalsContact O-N 3.14Å; E172-K175 WeakPolarHBondContact O-CB 3.37Å; E172-K175 PolarHBondContact O-N 3.41Å; K175-T177 PolarHBondContact O-N 2.91Å; K175-Q179 WeakPolarHBondContact O-CB 3.21Å; K175-Q179 PolarHBondContact O-N 3.49Å; K175-Q179 VanDerWaalsContact O-N 3.14Å
176E93.3Very high96.5Very high177 Ų17763.9 Ų63.983%0.82730%0.302SS*.Hα-helixtrans-64.8-24.1-179.7-63-175.4167.900113.8G174G174-E176 VanDerWaalsContact C-N 3.28Å; G174-E176 PolarHBondContact O-N 3.31Å; G174-E176 VanDerWaalsContact O-N 3.15Å
177T92.8Very high96.3Very high45 Ų4565.2 Ų65.228%0.27631%0.31SS..Hα-helixtrans-102.6-44.2-178.8-540000112.3G174 K175 R180G174-T177 PolarHBondContact O-N 2.81Å; K175-T177 PolarHBondContact O-N 2.91Å; T177-R180 VanDerWaalsContact O-CG 3.29Å; T177-R180 WeakPolarHBondContact O-CG 3.46Å
178L94Very high96.2Very high3 Ų366.9 Ų66.92%0.01632%0.318CS..Hα-helixtrans-82.8-28.7-172.1-63.8172.3000112.8V27 T30 W50 Y170 L171 G174V27-L178 HydrophobicContact CB-CD1 4.28Å; V27-L178 HydrophobicContact CB-CD2 4.11Å; V27-L178 HydrophobicContact CG1-CD1 3.89Å; V27-L178 HydrophobicContact CG1-CD2 4.07Å; T30-L178 HydrophobicContact CG2-CD2 4.13Å; W50-L178 HydrophobicContact CD2-CD1 4.42Å; W50-L178 HydrophobicContact CH2-CD1 4.25Å; W50-L178 HydrophobicContact CZ2-CD1 3.82Å; W50-L178 HydrophobicContact CZ2-CD2 4Å; W50-L178 HydrophobicContact CZ2-CG 4.28Å; Y170-L178 WeakPolarHBondContact O-CD1 3.36Å; L171-L178 HydrophobicContact CD2-CB 4.14Å; L171-L178 HydrophobicContact CD2-CD1 4.32Å; G174-L178 WeakPolarHBondContact O-CB 3.47Å; G174-L178 PolarHBondContact O-N 2.93Å
179Q92.9Very high96Very high86 Ų8662.8 Ų62.840%0.40231%0.307SS..SBendtrans-105.614.4179.1-54.3179.836.900112.1L171 K175L171-Q179 PolarHBondContact O-NE2 2.71Å; K175-Q179 WeakPolarHBondContact O-CB 3.21Å; K175-Q179 PolarHBondContact O-N 3.49Å; K175-Q179 VanDerWaalsContact O-N 3.14Å
180R94.6Very high95.8Very high78 Ų7859.9 Ų59.929%0.29430%0.299SS..  trans-77.9158.8171.182-171.8171.8-177.23.2110T177 D182 Y208 G238T177-R180 VanDerWaalsContact O-CG 3.29Å; T177-R180 WeakPolarHBondContact O-CG 3.46Å; R180-D182 IonicContact CZ-OD2 3.3Å; R180-D182 IonicContact NE-OD2 3.4Å; R180-D182 PolarHBondContact NE-OD2 2.96Å; R180-Y208 HydrophobicContact CG-CD1 3.79Å; R180-Y208 HydrophobicContact CG-CE1 4.24Å; R180-Y208 WeakPolarHBondContact O-CD1 3.22Å; R180-G238 PolarHBondContact NH2-O 2.94Å
181T95.4Very high95.6Very high60 Ų6064 Ų6437%0.36832%0.318SS..  trans-137.8116.8170.8-36.10000108.8Y208 E263T181-Y208 WeakPolarHBondContact CA-O 3.49Å; T181-Y208 WeakPolarHBondContact CG2-O 3.29Å; T181-E263 HydrophobicContact CG2-CB 4.06Å; T181-E263 HydrophobicContact CG2-CG 4.16Å
182D96.6Very high95.3Very high55 Ų5567.1 Ų67.129%0.29435%0.346SS..BIsolated β-bridgetrans-105.7116.1-178-62.4-37.3000108.4R180 F207 Y208 H262R180-D182 IonicContact CZ-OD2 3.3Å; R180-D182 IonicContact NE-OD2 3.4Å; R180-D182 PolarHBondContact NE-OD2 2.96Å; D182-F207 VanDerWaalsContact O-CA 3.31Å; D182-F207 WeakPolarHBondContact O-CA 3.34Å; D182-F207 WeakPolarHBondContact O-CB 3.38Å; D182-Y208 PolarHBondContact N-O 3.5Å; D182-Y208 PolarHBondContact O-N 2.75Å; D182-H262 PolarHBondContact O-CE1 3.2Å
183A97.9Very high94.8Very high48 Ų4865.4 Ų65.440%0.39734%0.344SS..  trans-65.9141179.900000111.6K185 G264 L265A183-K185 PolarHBondContact O-N 3.05Å; A183-G264 WeakPolarHBondContact CB-O 3.49Å; A183-L265 HydrophobicContact CB-CD2 3.99Å
184P98.2Very high94.5Very high9 Ų965.7 Ų65.76%0.05835%0.349CS..  trans-64.9131.3178.927-34.8000111.9T186 A204 F207 I212 V260 H262 L265P184-T186 HydrophobicContact CB-CG2 4.09Å; P184-T186 HydrophobicContact CG-CG2 4.27Å; P184-T186 PolarHBondContact O-N 3.37Å; P184-A204 HydrophobicContact CB-CB 3.9Å; P184-F207 HydrophobicContact CB-CB 3.84Å; P184-F207 HydrophobicContact CB-CD1 3.98Å; P184-F207 HydrophobicContact CB-CG 4.16Å; P184-I212 HydrophobicContact CB-CD1 4.06Å; P184-I212 HydrophobicContact CG-CD1 4.11Å; P184-V260 HydrophobicContact CG-CG1 3.99Å; P184-H262 HydrophobicContact CG-CB 4.13Å; P184-L265 HydrophobicContact CG-CD1 3.87Å; P184-L265 HydrophobicContact CG-CD2 4.41Å; P184-L265 HydrophobicContact CG-CG 4.2Å
185K98Very high94Very high143 Ų14372.7 Ų72.762%0.62239%0.386SS*.EExtended strand (participates in β ladder)trans-76.6109164.6-64.9176.8-173.8168.20107.7A183 L205A183-K185 PolarHBondContact O-N 3.05Å; K185-L205 HydrophobicContact CB-CB 4.5Å; K185-L205 PolarHBondContact N-O 3.38Å; K185-L205 PolarHBondContact O-N 3.36Å
186T97.5Very high93.9Very high39 Ų3974.4 Ų74.424%0.23940%0.395CS..EExtended strand (participates in β ladder)trans-105.6144.4-17556.50000112P184 W203 A204 V260 L269 L271P184-T186 HydrophobicContact CB-CG2 4.09Å; P184-T186 HydrophobicContact CG-CG2 4.27Å; P184-T186 PolarHBondContact O-N 3.37Å; T186-W203 WeakPolarHBondContact CA-O 3.34Å; T186-W203 WeakPolarHBondContact CB-O 3.32Å; T186-A204 HydrophobicContact CG2-CB 4.38Å; T186-V260 HydrophobicContact CG2-CG1 4.29Å; T186-V260 HydrophobicContact CG2-CG2 4.14Å; T186-L269 HydrophobicContact CG2-CD1 4.49Å; T186-L271 HydrophobicContact CG2-CD1 4.08Å
187H95.2Very high93.9Very high79 Ų7970.4 Ų70.437%0.36638%0.377SS..EExtended strand (participates in β ladder)trans-156.8166.717168.5-78000110W203H187-W203 AromaticContact CD2-CD1 3.89Å; H187-W203 WeakPolarHBondContact CE1-CB 3.36Å; H187-W203 AromaticContact CE1-CD1 3.79Å; H187-W203 AromaticContact CE1-CG 3.49Å; H187-W203 VanDerWaalsContact CE1-CG 3.49Å; H187-W203 PolarHBondContact N-O 3.5Å; H187-W203 AromaticContact NE2-CD1 3.4Å; H187-W203 AromaticContact NE2-CG 3.58Å; H187-W203 AromaticContact NE2-NE1 3.95Å; H187-W203 PolarHBondContact O-N 3.07Å
188M95.6Very high94Very high34 Ų3468.2 Ų68.217%0.16736%0.364CS..EExtended strand (participates in β ladder)trans-119.6138.4178.1-64.6178.392.500110.8R201 W216 C258 L271 W273M188-R201 CarbonylContact C-O 3.57Å; M188-R201 WeakPolarHBondContact CA-O 3.35Å; M188-W216 HydrophobicContact CE-CH2 3.08Å; M188-W216 HydrophobicContact CE-CZ2 3.92Å; M188-W216 HydrophobicContact CE-CZ3 3.65Å; M188-C258 HydrophobicContact CE-CB 4.21Å; M188-L271 HydrophobicContact CG-CB 4.25Å; M188-L271 HydrophobicContact SD-CB 3.66Å; M188-W273 HydrophobicContact CE-CB 4.34Å; M188-W273 HydrophobicContact SD-CB 4.34Å; M188-W273 PolarHBondContact SD-N 3.13Å
189T94.6Very high94.1Very high35 Ų3569.2 Ų69.222%0.21537%0.37CS..EExtended strand (participates in β ladder)trans-115140.6171.653.40000109.4R201 W203T189-R201 PolarHBondContact N-O 2.72Å; T189-R201 PolarHBondContact O-N 3.11Å; T189-R201 WeakPolarHBondContact OG1-CB 3.35Å; T189-W203 PolarHBondContact OG1-NE1 2.77Å
190H94.3Very high94.3Very high64 Ų6465.1 Ų65.130%0.29635%0.351SS..EExtended strand (participates in β ladder)trans-116.1128.3176.5165.1-78.2000109.1A198 L200 W273H190-A198 WeakPolarHBondContact NE2-CB 3.39Å; H190-L200 HydrophobicContact CB-CD2 3.96Å; H190-W273 HydrophobicContact CB-CZ2 4.12Å; H190-W273 AromaticContact CG-CE2 3.98Å; H190-W273 AromaticContact CG-CZ2 3.96Å
191H92.7Very high94.4Very high86 Ų8663.9 Ų63.940%0.39835%0.346SS..EExtended strand (participates in β ladder)trans-125.8112.8177.5-60.4-72.6000109V193 A198 T199 R201H191-V193 PolarHBondContact O-N 2.79Å; H191-A198 CarbonylContact O-C 3.55Å; H191-A198 WeakPolarHBondContact O-CA 3.5Å; H191-T199 PolarHBondContact N-O 2.98Å; H191-T199 PolarHBondContact O-N 3.17Å; H191-R201 PolarHBondContact NE2-NH1 2.89Å
192A90.9Very high94.5Very high80 Ų8061 Ų6166%0.66133%0.328SS*.EExtended strand (participates in β ladder)trans-65.6127.7172.600000109.3
193V88.3Confident94.6Very high92 Ų9260.5 Ų60.556%0.55832%0.322SS*.  trans-98.3-41.4176.9-179.50000109.6H191 E197 T199H191-V193 PolarHBondContact O-N 2.79Å; V193-E197 PolarHBondContact N-O 3.14Å; V193-T199 VanDerWaalsContact CG2-OG1 3.31Å; V193-T199 WeakPolarHBondContact CG2-OG1 3.09Å
194S89.8Confident94.6Very high53 Ų5358.2 Ų58.237%0.37130%0.304SS..SBendtrans-149.7-178174.771.10000110.4H196 E197S194-H196 PolarHBondContact O-N 2.8Å; S194-H196 PolarHBondContact OG-N 3Å; S194-E197 PolarHBondContact N-O 3.35Å; S194-E197 VanDerWaalsContact O-O 3.07Å; S194-E197 PolarHBondContact OG-N 3.42Å
195D87.3Confident94.6Very high150 Ų15060.1 Ų60.180%0.80231%0.313SS*.SBendtrans-66.3-10.1172.5-65.5-21.5000113.4
196H91.7Very high94.6Very high146 Ų14655.2 Ų55.268%0.67630%0.297SS*.SBendtrans-115.5-15.2-176-57.2-42.7000113.4S194 P249 S250S194-H196 PolarHBondContact O-N 2.8Å; S194-H196 PolarHBondContact OG-N 3Å; H196-P249 CarbonylContact O-C 3.6Å; H196-P249 WeakPolarHBondContact O-CA 3.45Å; H196-S250 PolarHBondContact O-N 3.37Å; H196-S250 PolarHBondContact O-OG 2.95Å
197E94.1Very high94.6Very high93 Ų9353.4 Ų53.444%0.43529%0.285SS..EExtended strand (participates in β ladder)trans-144.4143.9-171.4-66.4-179.9173.200112.3V193 S194 V247 V248 S250V193-E197 PolarHBondContact N-O 3.14Å; S194-E197 PolarHBondContact N-O 3.35Å; S194-E197 VanDerWaalsContact O-O 3.07Å; S194-E197 PolarHBondContact OG-N 3.42Å; E197-V247 HydrophobicContact CB-CG1 4.16Å; E197-V247 HydrophobicContact CG-CG1 4.37Å; E197-V248 WeakPolarHBondContact CA-O 3.4Å; E197-S250 PolarHBondContact N-OG 3.03Å
198A94.3Very high94.7Very high0 Ų049.8 Ų49.80%027%0.269CS..EExtended strand (participates in β ladder)trans-132153.9171.300000110.6H190 H191 V248H190-A198 WeakPolarHBondContact NE2-CB 3.39Å; H191-A198 CarbonylContact O-C 3.55Å; H191-A198 WeakPolarHBondContact O-CA 3.5Å; A198-V248 HydrophobicContact CB-CG2 4.34Å; A198-V248 PolarHBondContact N-O 3Å; A198-V248 WeakPolarHBondContact O-CG2 3.48Å; A198-V248 PolarHBondContact O-N 3.32Å
199T96.1Very high94.7Very high24 Ų2449.2 Ų49.215%0.14727%0.267CS..EExtended strand (participates in β ladder)trans-96.7121.6168.1-550000108.9H191 V193 V246H191-T199 PolarHBondContact N-O 2.98Å; H191-T199 PolarHBondContact O-N 3.17Å; V193-T199 VanDerWaalsContact CG2-OG1 3.31Å; V193-T199 WeakPolarHBondContact CG2-OG1 3.09Å; T199-V246 WeakPolarHBondContact CA-O 3.22Å
200L96.9Very high94.8Very high0 Ų048.2 Ų48.20%026%0.263CS..EExtended strand (participates in β ladder)trans-94.1130.5164.9-62.5-178.7000108.8H190 W216 S245 V246 V248 E253 W273H190-L200 HydrophobicContact CB-CD2 3.96Å; L200-W216 HydrophobicContact CB-CH2 3.52Å; L200-W216 HydrophobicContact CB-CZ2 3.91Å; L200-W216 HydrophobicContact CB-CZ3 4.45Å; L200-W216 HydrophobicContact CD1-CH2 4.01Å; L200-W216 HydrophobicContact CD1-CZ3 4.27Å; L200-W216 HydrophobicContact CG-CH2 4.44Å; L200-S245 CarbonylContact O-C 3.58Å; L200-S245 WeakPolarHBondContact O-CA 3.46Å; L200-S245 WeakPolarHBondContact O-CB 3.42Å; L200-V246 HydrophobicContact CB-CG1 4.39Å; L200-V246 PolarHBondContact N-O 2.93Å; L200-V246 PolarHBondContact O-N 2.87Å; L200-V248 HydrophobicContact CD1-CG1 4Å; L200-V248 HydrophobicContact CD1-CG2 4.03Å; L200-V248 HydrophobicContact CG-CG1 4.2Å; L200-V248 HydrophobicContact CG-CG2 3.85Å; L200-E253 HydrophobicContact CD1-CB 4.06Å; L200-E253 HydrophobicContact CD1-CG 4.42Å; L200-E253 HydrophobicContact CD2-CG 4.29Å; L200-W273 HydrophobicContact CD1-CB 4.24Å; L200-W273 HydrophobicContact CD2-CB 3.96Å; L200-W273 HydrophobicContact CD2-CD2 4.32Å; L200-W273 HydrophobicContact CD2-CG 3.81Å
201R97.4Very high94.9Very high52 Ų5252.1 Ų52.120%0.19628%0.281CS..EExtended strand (participates in β ladder)trans-123.4125.3175.1-177.6-177.3-64.5123.2-1110.1M188 T189 H191 W203 W243 A244M188-R201 CarbonylContact C-O 3.57Å; M188-R201 WeakPolarHBondContact CA-O 3.35Å; T189-R201 PolarHBondContact N-O 2.72Å; T189-R201 PolarHBondContact O-N 3.11Å; T189-R201 WeakPolarHBondContact OG1-CB 3.35Å; H191-R201 PolarHBondContact NE2-NH1 2.89Å; R201-W203 HydrophobicContact CG-CZ2 4.41Å; R201-W243 HydrophobicContact CG-CB 4.03Å; R201-W243 HydrophobicContact CG-CD2 4.16Å; R201-W243 HydrophobicContact CG-CE3 3.92Å; R201-W243 HydrophobicContact CG-CG 4.27Å; R201-A244 WeakPolarHBondContact CA-O 3.45Å
202C97.8Very high95.2Very high0 Ų048.5 Ų48.50%027%0.265CS..EExtended strand (participates in β ladder)trans-97.3123176.2-1760000109.1W216 W243 A244 C258C202-W216 HydrophobicContact CB-CZ2 3.82Å; C202-W243 CarbonylContact O-C 3.59Å; C202-W243 WeakPolarHBondContact O-CA 3.21Å; C202-W243 VanDerWaalsContact O-CB 3.23Å; C202-W243 WeakPolarHBondContact O-CB 3.06Å; C202-A244 PolarHBondContact N-O 2.04Å; C202-A244 PolarHBondContact O-N 3.4Å; C202-C258 HydrophobicContact CB-CB 3.49Å; C202-C258 VanDerWaalsContact CB-CB 3.49Å; C202-C258 WeakPolarHBondContact CB-SG 3.32Å; C202-C258 WeakPolarHBondContact SG-CB 3.42Å; C202-C258 CovalentContact SG-SG 2.03Å; C202-C258 PolarHBondContact SG-SG 3.48Å
203W98.1Very high95.5Very high44 Ų4447.4 Ų47.417%0.16725%0.25CC..EExtended strand (participates in β ladder)trans-106.3140.8-179.1-67.688.2000110.6T186 H187 T189 R201 L205 W243T186-W203 WeakPolarHBondContact CA-O 3.34Å; T186-W203 WeakPolarHBondContact CB-O 3.32Å; H187-W203 AromaticContact CD2-CD1 3.89Å; H187-W203 WeakPolarHBondContact CE1-CB 3.36Å; H187-W203 AromaticContact CE1-CD1 3.79Å; H187-W203 AromaticContact CE1-CG 3.49Å; H187-W203 VanDerWaalsContact CE1-CG 3.49Å; H187-W203 PolarHBondContact N-O 3.5Å; H187-W203 AromaticContact NE2-CD1 3.4Å; H187-W203 AromaticContact NE2-CG 3.58Å; H187-W203 AromaticContact NE2-NE1 3.95Å; H187-W203 PolarHBondContact O-N 3.07Å; T189-W203 PolarHBondContact OG1-NE1 2.77Å; R201-W203 HydrophobicContact CG-CZ2 4.41Å; W203-L205 HydrophobicContact CE3-CD2 4Å; W203-W243 HydrophobicContact CD2-CB 3.98Å; W203-W243 HydrophobicContact CD2-CG 4.47Å; W203-W243 HydrophobicContact CE3-CB 3.86Å; W203-W243 AromaticContact CE3-CD1 3.83Å; W203-W243 HydrophobicContact CE3-CG 4.14Å; W203-W243 HydrophobicContact CG-CB 4.4Å; W203-W243 AromaticContact CH2-CD1 3.73Å; W203-W243 HydrophobicContact CH2-CG 4.31Å; W203-W243 HydrophobicContact CZ3-CB 4.29Å; W203-W243 AromaticContact CZ3-CD1 3.38Å; W203-W243 HydrophobicContact CZ3-CG 4.06Å
204A98.4Very high96Very high0 Ų043.3 Ų43.30%023%0.225CC..EExtended strand (participates in β ladder)trans-124.2121.1163.400000107.9P184 T186 F207 I212 L214 Q241 K242P184-A204 HydrophobicContact CB-CB 3.9Å; T186-A204 HydrophobicContact CG2-CB 4.38Å; A204-F207 HydrophobicContact CB-CD1 4.12Å; A204-F207 HydrophobicContact CB-CE1 3.9Å; A204-F207 WeakPolarHBondContact O-CE1 3.35Å; A204-I212 HydrophobicContact CB-CD1 3.69Å; A204-L214 HydrophobicContact CB-CD1 4.1Å; A204-L214 HydrophobicContact CB-CD2 4.28Å; A204-Q241 CarbonylContact O-C 3.6Å; A204-Q241 VanDerWaalsContact O-CA 3.27Å; A204-Q241 WeakPolarHBondContact O-CA 3.29Å; A204-K242 PolarHBondContact N-O 3.2Å; A204-K242 PolarHBondContact O-N 2.86Å; A204-K242 VanDerWaalsContact O-O 3.08Å
205L98.2Very high96.3Very high48 Ų4842.8 Ų42.825%0.25122%0.219SC..EExtended strand (participates in β ladder)trans-127.8155.1-175.2-59179.4000111.3K185 W203 F207 Q241K185-L205 HydrophobicContact CB-CB 4.5Å; K185-L205 PolarHBondContact N-O 3.38Å; K185-L205 PolarHBondContact O-N 3.36Å; W203-L205 HydrophobicContact CE3-CD2 4Å; L205-F207 VanDerWaalsContact C-N 3.32Å; L205-F207 PolarHBondContact O-N 2.88Å; L205-Q241 HydrophobicContact CD2-CB 3.55Å
206S97.6Very high96.8Very high41 Ų4135.7 Ų35.729%0.28718%0.182SC..EExtended strand (participates in β ladder)trans54.642.4171.2-55.40000113.9T239 F240S206-T239 WeakPolarHBondContact CA-OG1 3.45Å; S206-F240 PolarHBondContact N-O 2.83Å
207F97.8Very high97.1Very high0 Ų030.8 Ų30.80%016%0.159CC..EExtended strand (participates in β ladder)trans-107.7158.617760.9-90000112.4D182 P184 A204 L205 P209 I212 T232 T239 F240 K242 H262D182-F207 VanDerWaalsContact O-CA 3.31Å; D182-F207 WeakPolarHBondContact O-CA 3.34Å; D182-F207 WeakPolarHBondContact O-CB 3.38Å; P184-F207 HydrophobicContact CB-CB 3.84Å; P184-F207 HydrophobicContact CB-CD1 3.98Å; P184-F207 HydrophobicContact CB-CG 4.16Å; A204-F207 HydrophobicContact CB-CD1 4.12Å; A204-F207 HydrophobicContact CB-CE1 3.9Å; A204-F207 WeakPolarHBondContact O-CE1 3.35Å; L205-F207 VanDerWaalsContact C-N 3.32Å; L205-F207 PolarHBondContact O-N 2.88Å; F207-P209 VanDerWaalsContact CD2-O 3.27Å; F207-P209 WeakPolarHBondContact CD2-O 3.37Å; F207-I212 HydrophobicContact CD1-CD1 3.96Å; F207-I212 HydrophobicContact CD2-CB 4.31Å; F207-I212 HydrophobicContact CD2-CD1 4.02Å; F207-I212 HydrophobicContact CE1-CD1 3.84Å; F207-I212 HydrophobicContact CE1-CG2 4.41Å; F207-I212 HydrophobicContact CE2-CB 3.73Å; F207-I212 HydrophobicContact CE2-CD1 3.93Å; F207-I212 HydrophobicContact CE2-CG1 4.41Å; F207-I212 HydrophobicContact CE2-CG2 3.59Å; F207-I212 HydrophobicContact CG-CD1 4.06Å; F207-I212 HydrophobicContact CZ-CB 4.08Å; F207-I212 HydrophobicContact CZ-CD1 3.86Å; F207-I212 HydrophobicContact CZ-CG2 3.5Å; F207-I212 VanDerWaalsContact CZ-CG2 3.5Å; F207-T232 HydrophobicContact CE2-CG2 4.15Å; F207-T232 HydrophobicContact CZ-CG2 3.9Å; F207-T239 CarbonylContact O-C 3.59Å; F207-T239 WeakPolarHBondContact O-CA 3.45Å; F207-T239 WeakPolarHBondContact O-CB 3.43Å; F207-F240 VanDerWaalsContact CD1-O 3.3Å; F207-F240 WeakPolarHBondContact CD1-O 3.36Å; F207-F240 HydrophobicContact CD2-CB 3.95Å; F207-F240 HydrophobicContact CE1-CB 4.2Å; F207-F240 WeakPolarHBondContact CE1-O 3.42Å; F207-F240 HydrophobicContact CE2-CB 3.49Å; F207-F240 VanDerWaalsContact CE2-CB 3.49Å; F207-F240 HydrophobicContact CE2-CG 4.46Å; F207-F240 HydrophobicContact CG-CB 4.45Å; F207-F240 HydrophobicContact CZ-CB 3.61Å; F207-F240 PolarHBondContact N-O 2.82Å; F207-F240 PolarHBondContact O-N 3.01Å; F207-K242 HydrophobicContact CE1-CB 4.37Å; F207-K242 HydrophobicContact CZ-CB 4.16Å; F207-H262 AromaticContact CD2-CD2 3.79Å; F207-H262 AromaticContact CD2-NE2 3.58Å
208Y96.7Very high97.2Very high3 Ų330 Ų301%0.01215%0.152CC..BIsolated β-bridgetrans-152.3136173.6-179.1-85.3000109T30 R180 T181 D182 G238 F240 H262T30-Y208 PolarHBondContact OG1-OH 3.04Å; R180-Y208 HydrophobicContact CG-CD1 3.79Å; R180-Y208 HydrophobicContact CG-CE1 4.24Å; R180-Y208 WeakPolarHBondContact O-CD1 3.22Å; T181-Y208 WeakPolarHBondContact CA-O 3.49Å; T181-Y208 WeakPolarHBondContact CG2-O 3.29Å; D182-Y208 PolarHBondContact N-O 3.5Å; D182-Y208 PolarHBondContact O-N 2.75Å; Y208-G238 WeakPolarHBondContact CD2-O 3.48Å; Y208-F240 HydrophobicContact CD2-CD2 4.37Å; Y208-F240 AromaticContact CD2-CE2 3.9Å; Y208-F240 HydrophobicContact CD2-CE2 3.9Å; Y208-F240 HydrophobicContact CE2-CE2 4.3Å; Y208-H262 PolarHBondContact O-CE1 3.34Å
209P96Very high97.2Very high22 Ų2234.7 Ų34.714%0.14318%0.177CC..SBendcis-74.4-176.34.632.4-37.6000114.1F207 E211 H262F207-P209 VanDerWaalsContact CD2-O 3.27Å; F207-P209 WeakPolarHBondContact CD2-O 3.37Å; P209-E211 VanDerWaalsContact C-N 3.3Å; P209-E211 PolarHBondContact O-N 3.27Å; P209-H262 PolarHBondContact O-NE2 3.06Å
210A96.9Very high97Very high15 Ų1535.9 Ų35.912%0.12419%0.194CC..SBendtrans-71-24.3-177.300000113.7D29 I212 T232 F240D29-A210 HydrophobicContact CB-CB 4.16Å; D29-A210 VanDerWaalsContact CG-CB 3.48Å; D29-A210 VanDerWaalsContact OD2-CB 3.31Å; D29-A210 WeakPolarHBondContact OD2-CB 3.46Å; D29-A210 PolarHBondContact OD2-N 3.01Å; A210-I212 PolarHBondContact O-N 3.02Å; A210-T232 HydrophobicContact CB-CG2 4.26Å; A210-T232 WeakPolarHBondContact O-CG2 3.38Å; A210-F240 HydrophobicContact CB-CD1 3.71Å; A210-F240 HydrophobicContact CB-CD2 3.75Å; A210-F240 HydrophobicContact CB-CE1 3.68Å; A210-F240 HydrophobicContact CB-CE2 3.73Å; A210-F240 HydrophobicContact CB-CG 3.77Å; A210-F240 HydrophobicContact CB-CZ 3.73Å
211E96.6Very high96.9Very high145 Ų14542.1 Ų42.168%0.67822%0.223SC*.  trans-66.6113.5-178.5-171.559.1-145.700110.7P209 H262P209-E211 VanDerWaalsContact C-N 3.3Å; P209-E211 PolarHBondContact O-N 3.27Å; E211-H262 PolarHBondContact O-CD2 3.46Å; E211-H262 VanDerWaalsContact O-CD2 3.27Å
212I97.8Very high96.8Very high10 Ų1044.2 Ų44.25%0.05124%0.238CC..  trans-149.3142.8-179.4-164.2170.4000109.5P184 A204 F207 A210 L214 K242 V260 Q261 H262P184-I212 HydrophobicContact CB-CD1 4.06Å; P184-I212 HydrophobicContact CG-CD1 4.11Å; A204-I212 HydrophobicContact CB-CD1 3.69Å; F207-I212 HydrophobicContact CD1-CD1 3.96Å; F207-I212 HydrophobicContact CD2-CB 4.31Å; F207-I212 HydrophobicContact CD2-CD1 4.02Å; F207-I212 HydrophobicContact CE1-CD1 3.84Å; F207-I212 HydrophobicContact CE1-CG2 4.41Å; F207-I212 HydrophobicContact CE2-CB 3.73Å; F207-I212 HydrophobicContact CE2-CD1 3.93Å; F207-I212 HydrophobicContact CE2-CG1 4.41Å; F207-I212 HydrophobicContact CE2-CG2 3.59Å; F207-I212 HydrophobicContact CG-CD1 4.06Å; F207-I212 HydrophobicContact CZ-CB 4.08Å; F207-I212 HydrophobicContact CZ-CD1 3.86Å; F207-I212 HydrophobicContact CZ-CG2 3.5Å; F207-I212 VanDerWaalsContact CZ-CG2 3.5Å; A210-I212 PolarHBondContact O-N 3.02Å; I212-L214 HydrophobicContact CD1-CD1 3.71Å; I212-L214 HydrophobicContact CG1-CD1 3.67Å; I212-L214 HydrophobicContact CG2-CD1 4.14Å; I212-K242 HydrophobicContact CG2-CB 4.17Å; I212-K242 HydrophobicContact CG2-CD 3.57Å; I212-V260 HydrophobicContact CD1-CG1 3.96Å; I212-V260 HydrophobicContact CG1-CG1 4.3Å; I212-Q261 VanDerWaalsContact CG1-O 3.31Å; I212-Q261 WeakPolarHBondContact CG1-O 3.38Å; I212-H262 HydrophobicContact CD1-CB 4.27Å; I212-H262 HydrophobicContact CG1-CB 4.05Å
213T97.8Very high96.6Very high57 Ų5744.9 Ų44.935%0.3524%0.241SC..EExtended strand (participates in β ladder)trans-113.8124.4174.1-61.30000110.1T215 V260 Q261T213-T215 HydrophobicContact CG2-CG2 3.99Å; T213-V260 WeakPolarHBondContact O-CA 3.47Å; T213-Q261 PolarHBondContact N-O 3.2Å; T213-Q261 PolarHBondContact O-N 2.88Å
214L97.8Very high96.1Very high6 Ų647.9 Ų47.93%0.03127%0.265CS..EExtended strand (participates in β ladder)trans-117.9121.9172.5-87.662.4000108.5A204 I212 L229 K242 A244 H259 V260A204-L214 HydrophobicContact CB-CD1 4.1Å; A204-L214 HydrophobicContact CB-CD2 4.28Å; I212-L214 HydrophobicContact CD1-CD1 3.71Å; I212-L214 HydrophobicContact CG1-CD1 3.67Å; I212-L214 HydrophobicContact CG2-CD1 4.14Å; L214-L229 HydrophobicContact CB-CD1 4.06Å; L214-K242 HydrophobicContact CD1-CD 4.3Å; L214-K242 HydrophobicContact CD2-CB 4.37Å; L214-K242 HydrophobicContact CD2-CG 4.41Å; L214-A244 HydrophobicContact CB-CB 4.08Å; L214-A244 HydrophobicContact CD2-CB 4.25Å; L214-H259 WeakPolarHBondContact CA-O 3.4Å; L214-V260 HydrophobicContact CD1-CG1 4.06Å; L214-V260 HydrophobicContact CG-CG2 4.31Å
215T97.1Very high95.5Very high42 Ų4257.2 Ų57.226%0.25831%0.308SS..EExtended strand (participates in β ladder)trans-130.5151.7175.659.70000111.7T213 C258 H259T213-T215 HydrophobicContact CG2-CG2 3.99Å; T215-C258 CarbonylContact O-C 3.51Å; T215-C258 WeakPolarHBondContact O-CA 3.5Å; T215-H259 PolarHBondContact N-O 3.47Å; T215-H259 PolarHBondContact O-N 2.99Å
216W97.6Very high94.9Very high2 Ų260.2 Ų60.21%0.00833%0.325CS..EExtended strand (participates in β ladder)trans-107.7137172.1-82.8102.4000110.4M188 L200 C202 Q223 A244 V246 T257 C258M188-W216 HydrophobicContact CE-CH2 3.08Å; M188-W216 HydrophobicContact CE-CZ2 3.92Å; M188-W216 HydrophobicContact CE-CZ3 3.65Å; L200-W216 HydrophobicContact CB-CH2 3.52Å; L200-W216 HydrophobicContact CB-CZ2 3.91Å; L200-W216 HydrophobicContact CB-CZ3 4.45Å; L200-W216 HydrophobicContact CD1-CH2 4.01Å; L200-W216 HydrophobicContact CD1-CZ3 4.27Å; L200-W216 HydrophobicContact CG-CH2 4.44Å; C202-W216 HydrophobicContact CB-CZ2 3.82Å; W216-Q223 HydrophobicContact CB-CB 4.21Å; W216-Q223 PolarHBondContact O-N 2.85Å; W216-A244 PolarHBondContact NE1-O 2.81Å; W216-V246 HydrophobicContact CD2-CB 4.31Å; W216-V246 HydrophobicContact CD2-CG1 3.56Å; W216-V246 HydrophobicContact CE3-CG1 3.78Å; W216-V246 HydrophobicContact CG-CB 4.2Å; W216-V246 HydrophobicContact CG-CG1 3.97Å; W216-V246 HydrophobicContact CH2-CG1 4.09Å; W216-V246 HydrophobicContact CZ2-CG1 3.98Å; W216-V246 HydrophobicContact CZ3-CG1 4.05Å; W216-T257 WeakPolarHBondContact CA-O 3.21Å; W216-T257 VanDerWaalsContact CE3-C 3.49Å; W216-C258 HydrophobicContact CD2-CB 4.22Å; W216-C258 HydrophobicContact CE3-CB 4.2Å; W216-C258 HydrophobicContact CH2-CB 4.25Å; W216-C258 HydrophobicContact CZ2-CB 4.2Å; W216-C258 HydrophobicContact CZ3-CB 4.2Å
217Q97.4Very high94.6Very high42 Ų4259.5 Ų59.520%0.19632%0.318CS..EExtended strand (participates in β ladder)trans-124.1147.6172-68.6-173.1-9.900110.4E221 D222 Y256 T257 H259Q217-E221 CarbonylContact C-O 3.53Å; Q217-E221 VanDerWaalsContact CA-O 3.24Å; Q217-E221 WeakPolarHBondContact CA-O 3.44Å; Q217-D222 VanDerWaalsContact CG-OD1 3.26Å; Q217-D222 WeakPolarHBondContact CG-OD1 3.37Å; Q217-D222 PolarHBondContact NE2-OD1 2.64Å; Q217-Y256 CarbonylContact O-C 3.59Å; Q217-Y256 VanDerWaalsContact O-CA 3.27Å; Q217-Y256 WeakPolarHBondContact O-CA 3.39Å; Q217-T257 PolarHBondContact N-O 2.89Å; Q217-T257 PolarHBondContact O-N 3.22Å; Q217-H259 PolarHBondContact OE1-NE2 3.29Å; Q217-H259 VanDerWaalsContact OE1-NE2 3.17Å
218R96.6Very high94.5Very high78 Ų7865 Ų6529%0.29434%0.344SS..EExtended strand (participates in β ladder)trans-119.1117168-178.3-178.767.8-163.8-4.8108.3G220 E221 Q223 R255 Y256R218-G220 PolarHBondContact O-N 2.91Å; R218-E221 PolarHBondContact N-O 3.45Å; R218-E221 PolarHBondContact O-N 2.95Å; R218-Q223 HydrophobicContact CB-CG 3.96Å; R218-R255 WeakPolarHBondContact CA-O 3.15Å; R218-R255 HydrophobicContact CG-CB 4.31Å; R218-Y256 HydrophobicContact CB-CD1 4.1Å; R218-Y256 HydrophobicContact CB-CE1 3.96Å; R218-Y256 WeakPolarHBondContact CD-OH 3.4Å; R218-Y256 HydrophobicContact CG-CD2 4.41Å; R218-Y256 HydrophobicContact CG-CE1 4.22Å; R218-Y256 HydrophobicContact CG-CE2 4.08Å
219D94.5Very high94.5Very high97 Ų9769 Ų6952%0.51937%0.365SS..THydrogen-bonded Turntrans49.930.4-175.1-52.9-50.2000114.2R255D219-R255 PolarHBondContact N-O 2.9Å; D219-R255 IonicContact OD1-NE 3.46Å; D219-R255 PolarHBondContact OD1-NE 3.43Å; D219-R255 IonicContact OD2-CZ 3.07Å; D219-R255 IonicContact OD2-NE 2.78Å; D219-R255 PolarHBondContact OD2-NE 3.23Å; D219-R255 IonicContact OD2-NH2 2.61Å; D219-R255 PolarHBondContact OD2-NH2 3.45Å
220G91.8Very high94.5Very high49 Ų4969.6 Ų69.651%0.50537%0.368SS..THydrogen-bonded Turntrans91.5-2.6-177.900000115.6R218R218-G220 PolarHBondContact O-N 2.91Å
221E95.3Very high94.5Very high131 Ų13176.5 Ų76.561%0.61240%0.398SS*.EExtended strand (participates in β ladder)trans-96.3128175.6-63.4-175.7166.300111.8Q217 R218 Q223Q217-E221 CarbonylContact C-O 3.53Å; Q217-E221 VanDerWaalsContact CA-O 3.24Å; Q217-E221 WeakPolarHBondContact CA-O 3.44Å; R218-E221 PolarHBondContact N-O 3.45Å; R218-E221 PolarHBondContact O-N 2.95Å; E221-Q223 PolarHBondContact O-NE2 2.83Å
222D95.3Very high94.6Very high97 Ų9771.6 Ų71.652%0.51938%0.378SS..EExtended strand (participates in β ladder)trans-61.5137.5-179.9-68.7-25.3000112.5Q217Q217-D222 VanDerWaalsContact CG-OD1 3.26Å; Q217-D222 WeakPolarHBondContact CG-OD1 3.37Å; Q217-D222 PolarHBondContact NE2-OD1 2.64Å
223Q94.4Very high94.5Very high13 Ų1375.9 Ų75.96%0.06139%0.394CS..  trans-110.937.9-177.2-57.5-60.6-72.700112.4W216 R218 E221 Q225 D226 T227 Y256W216-Q223 HydrophobicContact CB-CB 4.21Å; W216-Q223 PolarHBondContact O-N 2.85Å; R218-Q223 HydrophobicContact CB-CG 3.96Å; E221-Q223 PolarHBondContact O-NE2 2.83Å; Q223-Q225 VanDerWaalsContact C-N 3.32Å; Q223-Q225 PolarHBondContact O-N 2.71Å; Q223-D226 PolarHBondContact O-N 2.7Å; Q223-T227 WeakPolarHBondContact O-CB 3.39Å; Q223-T227 PolarHBondContact O-N 2.7Å; Q223-T227 VanDerWaalsContact O-N 3.16Å; Q223-T227 PolarHBondContact O-OG1 2.86Å; Q223-Y256 HydrophobicContact CG-CE1 4.33Å
224T86.5Confident94.5Very high108 Ų10877.6 Ų77.666%0.66341%0.406SS*.THydrogen-bonded Turntrans-59-36.1-169.8-47.90000114.1
225Q86Confident94.4Very high195 Ų19579.6 Ų79.691%0.91142%0.424SS*.THydrogen-bonded Turntrans-75.5-30.2-178.8-66.4-1747.200113.3Q223 T227Q223-Q225 VanDerWaalsContact C-N 3.32Å; Q223-Q225 PolarHBondContact O-N 2.71Å; Q225-T227 VanDerWaalsContact C-N 3.34Å
226D84.9Confident94.2Very high112 Ų11281.3 Ų81.360%0.59945%0.45SS*.THydrogen-bonded Turntrans-94.73.2-178-57.9-46.5000112.3Q223Q223-D226 PolarHBondContact O-N 2.7Å
227T93.1Very high93.9Very high25 Ų2586.2 Ų86.215%0.15348%0.476CS..EExtended strand (participates in β ladder)trans-97.7121.4-179.4-64.50000110.7Q223 Q225 L229 A244 S245Q223-T227 WeakPolarHBondContact O-CB 3.39Å; Q223-T227 PolarHBondContact O-N 2.7Å; Q223-T227 VanDerWaalsContact O-N 3.16Å; Q223-T227 PolarHBondContact O-OG1 2.86Å; Q225-T227 VanDerWaalsContact C-N 3.34Å; T227-L229 HydrophobicContact CG2-CB 4.33Å; T227-L229 PolarHBondContact O-N 2.74Å; T227-A244 HydrophobicContact CG2-CB 4.02Å; T227-S245 CarbonylContact C-O 3.51Å; T227-S245 WeakPolarHBondContact CA-O 3.3Å
228E95.7Very high93.6Very high115 Ų11586.1 Ų86.154%0.53749%0.486SS..EExtended strand (participates in β ladder)trans-79.9107.2162.4-173.9-175.3-176.100108.7W243 A244 S245E228-W243 HydrophobicContact CB-CZ3 4.31Å; E228-W243 HydrophobicContact CG-CH2 3.97Å; E228-W243 HydrophobicContact CG-CZ3 3.89Å; E228-W243 WeakPolarHBondContact OE1-CH2 3.42Å; E228-A244 CarbonylContact O-C 3.52Å; E228-A244 WeakPolarHBondContact O-CA 3.41Å; E228-S245 PolarHBondContact N-O 3.2Å; E228-S245 PolarHBondContact O-N 2.87Å; E228-S245 PolarHBondContact OE2-OG 3.47Å
229L96.2Very high93.6Very high87 Ų8783 Ų8346%0.45548%0.476SS..EExtended strand (participates in β ladder)trans-110.3123.1177.3-175.967.9000109.5L214 T227 K242 A244L214-L229 HydrophobicContact CB-CD1 4.06Å; T227-L229 HydrophobicContact CG2-CB 4.33Å; T227-L229 PolarHBondContact O-N 2.74Å; L229-K242 HydrophobicContact CD1-CD 4.44Å; L229-A244 HydrophobicContact CD1-CB 3.61Å
230V96.3Very high93.8Very high35 Ų3579.5 Ų79.521%0.21246%0.456CS..PPolyproline II helixtrans-87.3152.4173.6-64.70000112.2K242 W243V230-K242 HydrophobicContact CG2-CG 4.46Å; V230-K242 VanDerWaalsContact O-CE 3.25Å; V230-K242 WeakPolarHBondContact O-CE 3Å; V230-K242 WeakPolarHBondContact O-CG 3.44Å; V230-K242 PolarHBondContact O-NZ 2.77Å; V230-W243 HydrophobicContact CB-CD2 4.47Å; V230-W243 HydrophobicContact CB-CZ2 4.36Å; V230-W243 HydrophobicContact CG1-CD2 3.97Å; V230-W243 HydrophobicContact CG1-CE3 4.23Å; V230-W243 HydrophobicContact CG1-CH2 3.49Å; V230-W243 VanDerWaalsContact CG1-CH2 3.49Å; V230-W243 HydrophobicContact CG1-CZ2 3.17Å; V230-W243 HydrophobicContact CG1-CZ3 3.99Å; V230-W243 HydrophobicContact CG2-CD2 3.7Å; V230-W243 HydrophobicContact CG2-CE3 4.39Å; V230-W243 HydrophobicContact CG2-CG 3.71Å; V230-W243 HydrophobicContact CG2-CZ2 4.34Å; V230-W243 WeakPolarHBondContact CG2-O 3.2Å; V230-W243 PolarHBondContact N-O 3.42Å
231E96.4Very high94.1Very high160 Ų16079.2 Ų79.275%0.74844%0.441SS*.PPolyproline II helixtrans-58.3148.5168.3-69.8-55.6150.400111.8R233E231-R233 PolarHBondContact O-N 2.76Å
232T97.7Very high94.2Very high42 Ų4273.7 Ų73.726%0.25842%0.415SS..PPolyproline II helixtrans-66.6129.6175.5-57.10000108.6F207 A210 F240 K242F207-T232 HydrophobicContact CE2-CG2 4.15Å; F207-T232 HydrophobicContact CZ-CG2 3.9Å; A210-T232 HydrophobicContact CB-CG2 4.26Å; A210-T232 WeakPolarHBondContact O-CG2 3.38Å; T232-F240 HydrophobicContact CG2-CB 3.79Å; T232-F240 HydrophobicContact CG2-CD1 3.93Å; T232-F240 HydrophobicContact CG2-CG 4.12Å; T232-K242 WeakPolarHBondContact OG1-CD 3.36Å; T232-K242 PolarHBondContact OG1-NZ 2.99Å
233R96.8Very high94.4Very high100 Ų10070.3 Ų70.338%0.37740%0.395SS..EExtended strand (participates in β ladder)trans-124.9144.3-175.369.1-168.6-179.5177.65.4111.4E231 F240 Q241E231-R233 PolarHBondContact O-N 2.76Å; R233-F240 WeakPolarHBondContact O-CA 3.23Å; R233-Q241 HydrophobicContact CG-CG 3.56Å; R233-Q241 PolarHBondContact N-O 3.04Å; R233-Q241 WeakPolarHBondContact O-CG 3.16Å; R233-Q241 PolarHBondContact O-N 3.34Å
234P96.8Very high94.5Very high93 Ų9369.7 Ų69.760%0.60439%0.392SS*.EExtended strand (participates in β ladder)trans-68.1144.9176.928.4-34.3000111.1F240P234-F240 HydrophobicContact CB-CE1 4.31Å
235A96Very high95Very high49 Ų4964.7 Ų64.741%0.40536%0.362SS..  trans-88.5-16.8173.400000112.9T239A235-T239 PolarHBondContact N-O 2.86Å
236G92.8Very high95.6Very high78 Ų7855.5 Ų55.580%0.80432%0.319SS*.SBendtrans97.1-8.8178.800000114.9
237D91.9Very high96.1Very high105 Ų10553.7 Ų53.756%0.56131%0.312SS*.SBendtrans-104.813.9176.962.4-2.3000113T239D237-T239 WeakPolarHBondContact OD1-CB 3.41Å; D237-T239 PolarHBondContact OD1-N 3.07Å; D237-T239 PolarHBondContact OD1-OG1 3.39Å
238G91.4Very high96.2Very high39 Ų3952.5 Ų52.540%0.40231%0.305SS..SBendtrans83.87.7-173.900000114.4R180 Y208R180-G238 PolarHBondContact NH2-O 2.94Å; Y208-G238 WeakPolarHBondContact CD2-O 3.48Å
239T96.5Very high96.2Very high13 Ų1349.2 Ų49.28%0.0829%0.293CS..  trans-110.6172.817173.60000112.1S206 F207 A235 D237S206-T239 WeakPolarHBondContact CA-OG1 3.45Å; F207-T239 CarbonylContact O-C 3.59Å; F207-T239 WeakPolarHBondContact O-CA 3.45Å; F207-T239 WeakPolarHBondContact O-CB 3.43Å; A235-T239 PolarHBondContact N-O 2.86Å; D237-T239 WeakPolarHBondContact OD1-CB 3.41Å; D237-T239 PolarHBondContact OD1-N 3.07Å; D237-T239 PolarHBondContact OD1-OG1 3.39Å
240F98Very high95.9Very high23 Ų2347.7 Ų47.710%0.10129%0.29CS..EExtended strand (participates in β ladder)trans-120.3163.4-177.5-63-84.4000112.4D29 S206 F207 Y208 A210 T232 R233 P234D29-F240 HydrophobicContact CB-CE2 3.82Å; D29-F240 HydrophobicContact CB-CZ 3.5Å; D29-F240 VanDerWaalsContact CB-CZ 3.5Å; S206-F240 PolarHBondContact N-O 2.83Å; F207-F240 VanDerWaalsContact CD1-O 3.3Å; F207-F240 WeakPolarHBondContact CD1-O 3.36Å; F207-F240 HydrophobicContact CD2-CB 3.95Å; F207-F240 HydrophobicContact CE1-CB 4.2Å; F207-F240 WeakPolarHBondContact CE1-O 3.42Å; F207-F240 HydrophobicContact CE2-CB 3.49Å; F207-F240 VanDerWaalsContact CE2-CB 3.49Å; F207-F240 HydrophobicContact CE2-CG 4.46Å; F207-F240 HydrophobicContact CG-CB 4.45Å; F207-F240 HydrophobicContact CZ-CB 3.61Å; F207-F240 PolarHBondContact N-O 2.82Å; F207-F240 PolarHBondContact O-N 3.01Å; Y208-F240 HydrophobicContact CD2-CD2 4.37Å; Y208-F240 AromaticContact CD2-CE2 3.9Å; Y208-F240 HydrophobicContact CD2-CE2 3.9Å; Y208-F240 HydrophobicContact CE2-CE2 4.3Å; A210-F240 HydrophobicContact CB-CD1 3.71Å; A210-F240 HydrophobicContact CB-CD2 3.75Å; A210-F240 HydrophobicContact CB-CE1 3.68Å; A210-F240 HydrophobicContact CB-CE2 3.73Å; A210-F240 HydrophobicContact CB-CG 3.77Å; A210-F240 HydrophobicContact CB-CZ 3.73Å; T232-F240 HydrophobicContact CG2-CB 3.79Å; T232-F240 HydrophobicContact CG2-CD1 3.93Å; T232-F240 HydrophobicContact CG2-CG 4.12Å; R233-F240 WeakPolarHBondContact O-CA 3.23Å; P234-F240 HydrophobicContact CB-CE1 4.31Å
241Q98.1Very high95.6Very high44 Ų4449.2 Ų49.221%0.20631%0.312CS..EExtended strand (participates in β ladder)trans-142.4145.7174.142.8167.8-20.300110A204 L205 R233A204-Q241 CarbonylContact O-C 3.6Å; A204-Q241 VanDerWaalsContact O-CA 3.27Å; A204-Q241 WeakPolarHBondContact O-CA 3.29Å; L205-Q241 HydrophobicContact CD2-CB 3.55Å; R233-Q241 HydrophobicContact CG-CG 3.56Å; R233-Q241 PolarHBondContact N-O 3.04Å; R233-Q241 WeakPolarHBondContact O-CG 3.16Å; R233-Q241 PolarHBondContact O-N 3.34Å
242K98.5Very high95.4Very high15 Ų1544.5 Ų44.57%0.06529%0.291CS..EExtended strand (participates in β ladder)trans-149.4153.9176.3-161.2-177.4-172.270.90108.8A204 F207 I212 L214 L229 V230 T232A204-K242 PolarHBondContact N-O 3.2Å; A204-K242 PolarHBondContact O-N 2.86Å; A204-K242 VanDerWaalsContact O-O 3.08Å; F207-K242 HydrophobicContact CE1-CB 4.37Å; F207-K242 HydrophobicContact CZ-CB 4.16Å; I212-K242 HydrophobicContact CG2-CB 4.17Å; I212-K242 HydrophobicContact CG2-CD 3.57Å; L214-K242 HydrophobicContact CD1-CD 4.3Å; L214-K242 HydrophobicContact CD2-CB 4.37Å; L214-K242 HydrophobicContact CD2-CG 4.41Å; L229-K242 HydrophobicContact CD1-CD 4.44Å; V230-K242 HydrophobicContact CG2-CG 4.46Å; V230-K242 VanDerWaalsContact O-CE 3.25Å; V230-K242 WeakPolarHBondContact O-CE 3Å; V230-K242 WeakPolarHBondContact O-CG 3.44Å; V230-K242 PolarHBondContact O-NZ 2.77Å; T232-K242 WeakPolarHBondContact OG1-CD 3.36Å; T232-K242 PolarHBondContact OG1-NZ 2.99Å
243W97.9Very high95.2Very high25 Ų2543.5 Ų43.510%0.09528%0.283CS..EExtended strand (participates in β ladder)trans-143.5157.6169.659.2-99.9000111.2R201 C202 W203 E228 V230 S245R201-W243 HydrophobicContact CG-CB 4.03Å; R201-W243 HydrophobicContact CG-CD2 4.16Å; R201-W243 HydrophobicContact CG-CE3 3.92Å; R201-W243 HydrophobicContact CG-CG 4.27Å; C202-W243 CarbonylContact O-C 3.59Å; C202-W243 WeakPolarHBondContact O-CA 3.21Å; C202-W243 VanDerWaalsContact O-CB 3.23Å; C202-W243 WeakPolarHBondContact O-CB 3.06Å; W203-W243 HydrophobicContact CD2-CB 3.98Å; W203-W243 HydrophobicContact CD2-CG 4.47Å; W203-W243 HydrophobicContact CE3-CB 3.86Å; W203-W243 AromaticContact CE3-CD1 3.83Å; W203-W243 HydrophobicContact CE3-CG 4.14Å; W203-W243 HydrophobicContact CG-CB 4.4Å; W203-W243 AromaticContact CH2-CD1 3.73Å; W203-W243 HydrophobicContact CH2-CG 4.31Å; W203-W243 HydrophobicContact CZ3-CB 4.29Å; W203-W243 AromaticContact CZ3-CD1 3.38Å; W203-W243 HydrophobicContact CZ3-CG 4.06Å; E228-W243 HydrophobicContact CB-CZ3 4.31Å; E228-W243 HydrophobicContact CG-CH2 3.97Å; E228-W243 HydrophobicContact CG-CZ3 3.89Å; E228-W243 WeakPolarHBondContact OE1-CH2 3.42Å; V230-W243 HydrophobicContact CB-CD2 4.47Å; V230-W243 HydrophobicContact CB-CZ2 4.36Å; V230-W243 HydrophobicContact CG1-CD2 3.97Å; V230-W243 HydrophobicContact CG1-CE3 4.23Å; V230-W243 HydrophobicContact CG1-CH2 3.49Å; V230-W243 VanDerWaalsContact CG1-CH2 3.49Å; V230-W243 HydrophobicContact CG1-CZ2 3.17Å; V230-W243 HydrophobicContact CG1-CZ3 3.99Å; V230-W243 HydrophobicContact CG2-CD2 3.7Å; V230-W243 HydrophobicContact CG2-CE3 4.39Å; V230-W243 HydrophobicContact CG2-CG 3.71Å; V230-W243 HydrophobicContact CG2-CZ2 4.34Å; V230-W243 WeakPolarHBondContact CG2-O 3.2Å; V230-W243 PolarHBondContact N-O 3.42Å; W243-S245 WeakPolarHBondContact CZ3-OG 3.33Å
244A97.8Very high95.1Very high0 Ų043.3 Ų43.30%029%0.286CS..EExtended strand (participates in β ladder)trans-132.7134.1173.700000108.6R201 C202 L214 W216 T227 E228 L229R201-A244 WeakPolarHBondContact CA-O 3.45Å; C202-A244 PolarHBondContact N-O 2.04Å; C202-A244 PolarHBondContact O-N 3.4Å; L214-A244 HydrophobicContact CB-CB 4.08Å; L214-A244 HydrophobicContact CD2-CB 4.25Å; W216-A244 PolarHBondContact NE1-O 2.81Å; T227-A244 HydrophobicContact CG2-CB 4.02Å; E228-A244 CarbonylContact O-C 3.52Å; E228-A244 WeakPolarHBondContact O-CA 3.41Å; L229-A244 HydrophobicContact CD1-CB 3.61Å
245S97.1Very high95Very high3 Ų344.1 Ų44.12%0.02128%0.277CS..EExtended strand (participates in β ladder)trans-126.9150.8174.651.20000113.9L200 T227 E228 W243L200-S245 CarbonylContact O-C 3.58Å; L200-S245 WeakPolarHBondContact O-CA 3.46Å; L200-S245 WeakPolarHBondContact O-CB 3.42Å; T227-S245 CarbonylContact C-O 3.51Å; T227-S245 WeakPolarHBondContact CA-O 3.3Å; E228-S245 PolarHBondContact N-O 3.2Å; E228-S245 PolarHBondContact O-N 2.87Å; E228-S245 PolarHBondContact OE2-OG 3.47Å; W243-S245 WeakPolarHBondContact CZ3-OG 3.33Å
246V97.1Very high95Very high3 Ų342.1 Ų42.12%0.01826%0.259CS..EExtended strand (participates in β ladder)trans-134.5143.1177.663.10000108.8T199 L200 W216 V248 Y256T199-V246 WeakPolarHBondContact CA-O 3.22Å; L200-V246 HydrophobicContact CB-CG1 4.39Å; L200-V246 PolarHBondContact N-O 2.93Å; L200-V246 PolarHBondContact O-N 2.87Å; W216-V246 HydrophobicContact CD2-CB 4.31Å; W216-V246 HydrophobicContact CD2-CG1 3.56Å; W216-V246 HydrophobicContact CE3-CG1 3.78Å; W216-V246 HydrophobicContact CG-CB 4.2Å; W216-V246 HydrophobicContact CG-CG1 3.97Å; W216-V246 HydrophobicContact CH2-CG1 4.09Å; W216-V246 HydrophobicContact CZ2-CG1 3.98Å; W216-V246 HydrophobicContact CZ3-CG1 4.05Å; V246-V248 HydrophobicContact CG1-CG1 3.77Å; V246-V248 HydrophobicContact CG2-CG1 4.48Å; V246-Y256 HydrophobicContact CG1-CD1 3.96Å; V246-Y256 HydrophobicContact CG1-CE1 4.4Å; V246-Y256 HydrophobicContact CG2-CD1 4.26Å; V246-Y256 HydrophobicContact CG2-CE1 3.93Å
247V96.3Very high95.3Very high74 Ų7438.9 Ų38.945%0.44822%0.224SC..EExtended strand (participates in β ladder)trans-84.3127.9170.7-178.70000108.2E197E197-V247 HydrophobicContact CB-CG1 4.16Å; E197-V247 HydrophobicContact CG-CG1 4.37Å
248V95.4Very high95.5Very high0 Ų033.9 Ų33.90%020%0.197CC..EExtended strand (participates in β ladder)trans-125.6142.5-176.5-52.80000110.4E197 A198 L200 V246 E253 Y256E197-V248 WeakPolarHBondContact CA-O 3.4Å; A198-V248 HydrophobicContact CB-CG2 4.34Å; A198-V248 PolarHBondContact N-O 3Å; A198-V248 WeakPolarHBondContact O-CG2 3.48Å; A198-V248 PolarHBondContact O-N 3.32Å; L200-V248 HydrophobicContact CD1-CG1 4Å; L200-V248 HydrophobicContact CD1-CG2 4.03Å; L200-V248 HydrophobicContact CG-CG1 4.2Å; L200-V248 HydrophobicContact CG-CG2 3.85Å; V246-V248 HydrophobicContact CG1-CG1 3.77Å; V246-V248 HydrophobicContact CG2-CG1 4.48Å; V248-E253 HydrophobicContact CG2-CG 3.93Å; V248-Y256 HydrophobicContact CB-CD2 4.04Å; V248-Y256 HydrophobicContact CB-CE2 3.79Å; V248-Y256 HydrophobicContact CG1-CD1 3.72Å; V248-Y256 HydrophobicContact CG1-CD2 3.59Å; V248-Y256 HydrophobicContact CG1-CE1 3.71Å; V248-Y256 HydrophobicContact CG1-CE2 3.61Å; V248-Y256 HydrophobicContact CG1-CG 3.64Å
249P94.9Very high95.8Very high45 Ų4533.6 Ų33.629%0.29219%0.185SC..EExtended strand (participates in β ladder)trans-63.7140.7170.1-20.432.4000111.1H196 G251 Q252H196-P249 CarbonylContact O-C 3.6Å; H196-P249 WeakPolarHBondContact O-CA 3.45Å; P249-G251 PolarHBondContact O-N 2.96Å; P249-Q252 HydrophobicContact CB-CB 4.4Å; P249-Q252 HydrophobicContact CB-CG 4.15Å; P249-Q252 WeakPolarHBondContact O-CB 3.02Å; P249-Q252 PolarHBondContact O-N 3.26Å
250S90.3Very high95.9Very high55 Ų5533 Ų3339%0.38518%0.182SC..THydrogen-bonded Turntrans-56.6132.2177.3-61.60000111.4H196 E197 Q252 E253H196-S250 PolarHBondContact O-N 3.37Å; H196-S250 PolarHBondContact O-OG 2.95Å; E197-S250 PolarHBondContact N-OG 3.03Å; S250-Q252 VanDerWaalsContact C-N 3.3Å; S250-E253 WeakPolarHBondContact CA-OE1 3.42Å
251G89.4Confident95.9Very high67 Ų6736.7 Ų36.769%0.69120%0.199SC*.THydrogen-bonded Turntrans84.3-3.3-177.200000114.7P249 E253P249-G251 PolarHBondContact O-N 2.96Å; G251-E253 WeakPolarHBondContact CA-OE2 3.03Å; G251-E253 VanDerWaalsContact N-CD 3.33Å; G251-E253 PolarHBondContact N-OE1 3.46Å; G251-E253 PolarHBondContact N-OE2 2.93Å
252Q93.6Very high95.9Very high62 Ų6235.3 Ų35.329%0.2919%0.193SC..  trans-103.94.9175.5-59.7-166.84000113.4P249 S250 Q254 R255 Y256P249-Q252 HydrophobicContact CB-CB 4.4Å; P249-Q252 HydrophobicContact CB-CG 4.15Å; P249-Q252 WeakPolarHBondContact O-CB 3.02Å; P249-Q252 PolarHBondContact O-N 3.26Å; S250-Q252 VanDerWaalsContact C-N 3.3Å; Q252-Q254 PolarHBondContact O-N 3.4Å; Q252-Q254 VanDerWaalsContact O-N 3.09Å; Q252-R255 WeakPolarHBondContact O-CB 3.43Å; Q252-R255 PolarHBondContact O-N 2.96Å; Q252-Y256 HydrophobicContact CB-CE2 4.44Å; Q252-Y256 WeakPolarHBondContact O-CD2 3.32Å
253E93.6Very high95.8Very high20 Ų2041.8 Ų41.89%0.09322%0.223CC..G310 helixtrans-54.5-36.1-174.4-59.178.8-175.300112.1L200 V248 S250 G251 R255 Y256 W273L200-E253 HydrophobicContact CD1-CB 4.06Å; L200-E253 HydrophobicContact CD1-CG 4.42Å; L200-E253 HydrophobicContact CD2-CG 4.29Å; V248-E253 HydrophobicContact CG2-CG 3.93Å; S250-E253 WeakPolarHBondContact CA-OE1 3.42Å; G251-E253 WeakPolarHBondContact CA-OE2 3.03Å; G251-E253 VanDerWaalsContact N-CD 3.33Å; G251-E253 PolarHBondContact N-OE1 3.46Å; G251-E253 PolarHBondContact N-OE2 2.93Å; E253-R255 VanDerWaalsContact C-N 3.25Å; E253-R255 PolarHBondContact O-N 3.43Å; E253-Y256 PolarHBondContact O-N 3.29Å; E253-Y256 VanDerWaalsContact O-N 3.16Å; E253-W273 HydrophobicContact CB-CD2 4.3Å; E253-W273 HydrophobicContact CB-CE3 3.5Å; E253-W273 VanDerWaalsContact CB-CE3 3.5Å; E253-W273 HydrophobicContact CB-CZ3 3.97Å; E253-W273 HydrophobicContact CG-CE3 3.9Å; E253-W273 HydrophobicContact CG-CZ3 4.02Å
254Q93.1Very high95.6Very high96 Ų9641.6 Ų41.645%0.44923%0.229SC..G310 helixtrans-69-18.6-179.1-64.2-57.3-43.400114.4Q252 Y256 W273Q252-Q254 PolarHBondContact O-N 3.4Å; Q252-Q254 VanDerWaalsContact O-N 3.09Å; Q254-Y256 VanDerWaalsContact C-N 3.26Å; Q254-W273 PolarHBondContact NE2-O 3.4Å
255R95.4Very high95.6Very high110 Ų11042.8 Ų42.842%0.41524%0.235SC..G310 helixtrans-77.6-17.2175.8-63.3175.267.8-176.58112R218 D219 Q252 E253R218-R255 WeakPolarHBondContact CA-O 3.15Å; R218-R255 HydrophobicContact CG-CB 4.31Å; D219-R255 PolarHBondContact N-O 2.9Å; D219-R255 IonicContact OD1-NE 3.46Å; D219-R255 PolarHBondContact OD1-NE 3.43Å; D219-R255 IonicContact OD2-CZ 3.07Å; D219-R255 IonicContact OD2-NE 2.78Å; D219-R255 PolarHBondContact OD2-NE 3.23Å; D219-R255 IonicContact OD2-NH2 2.61Å; D219-R255 PolarHBondContact OD2-NH2 3.45Å; Q252-R255 WeakPolarHBondContact O-CB 3.43Å; Q252-R255 PolarHBondContact O-N 2.96Å; E253-R255 VanDerWaalsContact C-N 3.25Å; E253-R255 PolarHBondContact O-N 3.43Å
256Y96.4Very high95.5Very high8 Ų849 Ų493%0.03128%0.276CS..EExtended strand (participates in β ladder)trans-96.8131.5-177.4-69.5-102.5000110.9Q217 R218 Q223 V246 V248 Q252 E253 Q254Q217-Y256 CarbonylContact O-C 3.59Å; Q217-Y256 VanDerWaalsContact O-CA 3.27Å; Q217-Y256 WeakPolarHBondContact O-CA 3.39Å; R218-Y256 HydrophobicContact CB-CD1 4.1Å; R218-Y256 HydrophobicContact CB-CE1 3.96Å; R218-Y256 WeakPolarHBondContact CD-OH 3.4Å; R218-Y256 HydrophobicContact CG-CD2 4.41Å; R218-Y256 HydrophobicContact CG-CE1 4.22Å; R218-Y256 HydrophobicContact CG-CE2 4.08Å; Q223-Y256 HydrophobicContact CG-CE1 4.33Å; V246-Y256 HydrophobicContact CG1-CD1 3.96Å; V246-Y256 HydrophobicContact CG1-CE1 4.4Å; V246-Y256 HydrophobicContact CG2-CD1 4.26Å; V246-Y256 HydrophobicContact CG2-CE1 3.93Å; V248-Y256 HydrophobicContact CB-CD2 4.04Å; V248-Y256 HydrophobicContact CB-CE2 3.79Å; V248-Y256 HydrophobicContact CG1-CD1 3.72Å; V248-Y256 HydrophobicContact CG1-CD2 3.59Å; V248-Y256 HydrophobicContact CG1-CE1 3.71Å; V248-Y256 HydrophobicContact CG1-CE2 3.61Å; V248-Y256 HydrophobicContact CG1-CG 3.64Å; Q252-Y256 HydrophobicContact CB-CE2 4.44Å; Q252-Y256 WeakPolarHBondContact O-CD2 3.32Å; E253-Y256 PolarHBondContact O-N 3.29Å; E253-Y256 VanDerWaalsContact O-N 3.16Å; Q254-Y256 VanDerWaalsContact C-N 3.26Å
257T97.4Very high95.5Very high10 Ų1056.8 Ų56.86%0.06131%0.309CS..EExtended strand (participates in β ladder)trans-124.3134.4176.445.50000110.5W216 Q217 H259 T270 L271 R272W216-T257 WeakPolarHBondContact CA-O 3.21Å; W216-T257 VanDerWaalsContact CE3-C 3.49Å; Q217-T257 PolarHBondContact N-O 2.89Å; Q217-T257 PolarHBondContact O-N 3.22Å; T257-H259 PolarHBondContact OG1-NE2 2.94Å; T257-T270 HydrophobicContact CG2-CG2 3.83Å; T257-L271 WeakPolarHBondContact CA-O 3.23Å; T257-R272 HydrophobicContact CG2-CG 3.5Å; T257-R272 VanDerWaalsContact CG2-CG 3.5Å; T257-R272 VanDerWaalsContact CG2-NE 3.28Å
258C97.8Very high95.5Very high0 Ų057.1 Ų57.10%031%0.313CS..EExtended strand (participates in β ladder)trans-94.2129.4168.7173.20000109.4M188 C202 T215 W216 T270 L271M188-C258 HydrophobicContact CE-CB 4.21Å; C202-C258 HydrophobicContact CB-CB 3.49Å; C202-C258 VanDerWaalsContact CB-CB 3.49Å; C202-C258 WeakPolarHBondContact CB-SG 3.32Å; C202-C258 WeakPolarHBondContact SG-CB 3.42Å; C202-C258 CovalentContact SG-SG 2.03Å; C202-C258 PolarHBondContact SG-SG 3.48Å; T215-C258 CarbonylContact O-C 3.51Å; T215-C258 WeakPolarHBondContact O-CA 3.5Å; W216-C258 HydrophobicContact CD2-CB 4.22Å; W216-C258 HydrophobicContact CE3-CB 4.2Å; W216-C258 HydrophobicContact CH2-CB 4.25Å; W216-C258 HydrophobicContact CZ2-CB 4.2Å; W216-C258 HydrophobicContact CZ3-CB 4.2Å; C258-T270 CarbonylContact O-C 3.54Å; C258-T270 WeakPolarHBondContact O-CA 3.04Å; C258-L271 HydrophobicContact CB-CB 4.26Å; C258-L271 PolarHBondContact N-O 2.94Å; C258-L271 PolarHBondContact O-N 2.98Å
259H97.8Very high95.6Very high33 Ų3360.1 Ų60.115%0.15333%0.329CS..EExtended strand (participates in β ladder)trans-108.6129.1177.3-63.8-105.9000109.5L214 T215 Q217 T257 L269 T270L214-H259 WeakPolarHBondContact CA-O 3.4Å; T215-H259 PolarHBondContact N-O 3.47Å; T215-H259 PolarHBondContact O-N 2.99Å; Q217-H259 PolarHBondContact OE1-NE2 3.29Å; Q217-H259 VanDerWaalsContact OE1-NE2 3.17Å; T257-H259 PolarHBondContact OG1-NE2 2.94Å; H259-L269 CarbonylContact C-O 3.55Å; H259-L269 WeakPolarHBondContact CA-O 3.26Å; H259-T270 PolarHBondContact ND1-OG1 2.79Å
260V98.3Very high95.7Very high0 Ų061.8 Ų61.80%034%0.339CS..EExtended strand (participates in β ladder)trans-121.4119.8-178.5-174.60000108.9P184 T186 I212 T213 L214 L265 P268 L269 L271P184-V260 HydrophobicContact CG-CG1 3.99Å; T186-V260 HydrophobicContact CG2-CG1 4.29Å; T186-V260 HydrophobicContact CG2-CG2 4.14Å; I212-V260 HydrophobicContact CD1-CG1 3.96Å; I212-V260 HydrophobicContact CG1-CG1 4.3Å; T213-V260 WeakPolarHBondContact O-CA 3.47Å; L214-V260 HydrophobicContact CD1-CG1 4.06Å; L214-V260 HydrophobicContact CG-CG2 4.31Å; V260-L265 HydrophobicContact CG1-CD1 4.17Å; V260-P268 WeakPolarHBondContact O-CA 3.3Å; V260-L269 HydrophobicContact CB-CB 4.35Å; V260-L269 PolarHBondContact N-O 3.28Å; V260-L269 PolarHBondContact O-N 2.89Å; V260-L271 HydrophobicContact CG2-CD1 3.89Å
261Q98.3Very high96Very high100 Ų10060.8 Ų60.847%0.46733%0.329SS..EExtended strand (participates in β ladder)trans-115.5128.3173.6-50-177.523.700109.1I212 T213 P268I212-Q261 VanDerWaalsContact CG1-O 3.31Å; I212-Q261 WeakPolarHBondContact CG1-O 3.38Å; T213-Q261 PolarHBondContact N-O 3.2Å; T213-Q261 PolarHBondContact O-N 2.88Å; Q261-P268 HydrophobicContact CG-CB 4.08Å; Q261-P268 HydrophobicContact CG-CG 4.15Å
262H97.9Very high96.2Very high15 Ų1565 Ų657%0.06932%0.324CS..  trans-154.9145-179.4-175.5-100.9000108.3D182 P184 F207 Y208 P209 E211 I212 G264 L265D182-H262 PolarHBondContact O-CE1 3.2Å; P184-H262 HydrophobicContact CG-CB 4.13Å; F207-H262 AromaticContact CD2-CD2 3.79Å; F207-H262 AromaticContact CD2-NE2 3.58Å; Y208-H262 PolarHBondContact O-CE1 3.34Å; P209-H262 PolarHBondContact O-NE2 3.06Å; E211-H262 PolarHBondContact O-CD2 3.46Å; E211-H262 VanDerWaalsContact O-CD2 3.27Å; I212-H262 HydrophobicContact CD1-CB 4.27Å; I212-H262 HydrophobicContact CG1-CB 4.05Å; H262-G264 WeakPolarHBondContact ND1-CA 3.33Å; H262-G264 PolarHBondContact ND1-N 3.2Å; H262-G264 PolarHBondContact O-N 2.91Å; H262-L265 HydrophobicContact CB-CD1 3.98Å; H262-L265 HydrophobicContact CB-CG 4.17Å; H262-L265 WeakPolarHBondContact O-CB 3.05Å; H262-L265 PolarHBondContact O-N 3.49Å
263E95.3Very high96.2Very high151 Ų15164.1 Ų64.171%0.70632%0.318SS*.THydrogen-bonded Turntrans-58.8-31.8-179.2-175.5174.4175.600112.6T181 L265T181-E263 HydrophobicContact CG2-CB 4.06Å; T181-E263 HydrophobicContact CG2-CG 4.16Å; E263-L265 PolarHBondContact O-N 3.39Å
264G95.1Very high95.7Very high22 Ų2270.9 Ų70.923%0.22735%0.349CS..THydrogen-bonded Turntrans-71.8-6.1177.200000114.6A183 H262A183-G264 WeakPolarHBondContact CB-O 3.49Å; H262-G264 WeakPolarHBondContact ND1-CA 3.33Å; H262-G264 PolarHBondContact ND1-N 3.2Å; H262-G264 PolarHBondContact O-N 2.91Å
265L97.3Very high95Very high24 Ų2470.1 Ų70.113%0.12635%0.353CS..SBendtrans-100.1126.3176.5-64.8170.5000109.7A183 P184 V260 H262 E263 K267 L269A183-L265 HydrophobicContact CB-CD2 3.99Å; P184-L265 HydrophobicContact CG-CD1 3.87Å; P184-L265 HydrophobicContact CG-CD2 4.41Å; P184-L265 HydrophobicContact CG-CG 4.2Å; V260-L265 HydrophobicContact CG1-CD1 4.17Å; H262-L265 HydrophobicContact CB-CD1 3.98Å; H262-L265 HydrophobicContact CB-CG 4.17Å; H262-L265 WeakPolarHBondContact O-CB 3.05Å; H262-L265 PolarHBondContact O-N 3.49Å; E263-L265 PolarHBondContact O-N 3.39Å; L265-K267 WeakPolarHBondContact CB-O 3.49Å; L265-K267 PolarHBondContact O-N 3.1Å; L265-L269 HydrophobicContact CD1-CB 4.41Å; L265-L269 HydrophobicContact CD1-CD1 3.86Å; L265-L269 HydrophobicContact CD1-CG 3.83Å; L265-L269 HydrophobicContact CD2-CD1 3.54Å; L265-L269 HydrophobicContact CD2-CG 3.87Å; L265-L269 HydrophobicContact CG-CD1 4.36Å; L265-L269 HydrophobicContact CG-CG 4.43Å
266P95.8Very high93.5Very high135 Ų13569.8 Ų69.888%0.87737%0.367SS*.SBendtrans-65.2-24.3178.127-34.8000112.5
267K96.4Very high91.2Very high165 Ų16575 Ų7572%0.71741%0.405SS*.SBendtrans-146.1151173.1-63.8-176.2-177.7178.10109L265 L269L265-K267 WeakPolarHBondContact CB-O 3.49Å; L265-K267 PolarHBondContact O-N 3.1Å; K267-L269 PolarHBondContact O-N 3.13Å
268P96.9Very high88.7Confident81 Ų8182.1 Ų82.153%0.52644%0.437SS..  trans-50.4137.4171.2-28.536.6000111.9V260 Q261V260-P268 WeakPolarHBondContact O-CA 3.3Å; Q261-P268 HydrophobicContact CG-CB 4.08Å; Q261-P268 HydrophobicContact CG-CG 4.15Å
269L97.2Very high86.1Confident63 Ų6387.1 Ų87.133%0.3347%0.47SS..EExtended strand (participates in β ladder)trans-90.5139.7173.9-68.3177000109.9T186 H259 V260 L265 K267T186-L269 HydrophobicContact CG2-CD1 4.49Å; H259-L269 CarbonylContact C-O 3.55Å; H259-L269 WeakPolarHBondContact CA-O 3.26Å; V260-L269 HydrophobicContact CB-CB 4.35Å; V260-L269 PolarHBondContact N-O 3.28Å; V260-L269 PolarHBondContact O-N 2.89Å; L265-L269 HydrophobicContact CD1-CB 4.41Å; L265-L269 HydrophobicContact CD1-CD1 3.86Å; L265-L269 HydrophobicContact CD1-CG 3.83Å; L265-L269 HydrophobicContact CD2-CD1 3.54Å; L265-L269 HydrophobicContact CD2-CG 3.87Å; L265-L269 HydrophobicContact CG-CD1 4.36Å; L265-L269 HydrophobicContact CG-CG 4.43Å; K267-L269 PolarHBondContact O-N 3.13Å
270T97.2Very high83.8Confident81 Ų8192 Ų9250%0.49750%0.502SS..EExtended strand (participates in β ladder)trans-118118.3171.3-560000108.3T257 C258 H259T257-T270 HydrophobicContact CG2-CG2 3.83Å; C258-T270 CarbonylContact O-C 3.54Å; C258-T270 WeakPolarHBondContact O-CA 3.04Å; H259-T270 PolarHBondContact ND1-OG1 2.79Å
271L96Very high81.7Confident34 Ų3496.9 Ų96.918%0.17853%0.527CS..EExtended strand (participates in β ladder)trans-106.8137.5-178.7-63.3151.1000109.4T186 M188 T257 C258 V260T186-L271 HydrophobicContact CG2-CD1 4.08Å; M188-L271 HydrophobicContact CG-CB 4.25Å; M188-L271 HydrophobicContact SD-CB 3.66Å; T257-L271 WeakPolarHBondContact CA-O 3.23Å; C258-L271 HydrophobicContact CB-CB 4.26Å; C258-L271 PolarHBondContact N-O 2.94Å; C258-L271 PolarHBondContact O-N 2.98Å; V260-L271 HydrophobicContact CG2-CD1 3.89Å
272R94.1Very high79.5Confident155 Ų15596.4 Ų96.459%0.58553%0.533SS*.EExtended strand (participates in β ladder)trans-119.3147.8168-73.5-175.9178.3156.9-0.3108.7T257 E274T257-R272 HydrophobicContact CG2-CG 3.5Å; T257-R272 VanDerWaalsContact CG2-CG 3.5Å; T257-R272 VanDerWaalsContact CG2-NE 3.28Å; R272-E274 PolarHBondContact O-N 2.79Å
273W92.3Very high77.6Confident44 Ų44101.3 Ų101.317%0.16756%0.558CS.*  trans-69125.8176.2173.971.5000109.2M188 H190 L200 E253 Q254 P275M188-W273 HydrophobicContact CE-CB 4.34Å; M188-W273 HydrophobicContact SD-CB 4.34Å; M188-W273 PolarHBondContact SD-N 3.13Å; H190-W273 HydrophobicContact CB-CZ2 4.12Å; H190-W273 AromaticContact CG-CE2 3.98Å; H190-W273 AromaticContact CG-CZ2 3.96Å; L200-W273 HydrophobicContact CD1-CB 4.24Å; L200-W273 HydrophobicContact CD2-CB 3.96Å; L200-W273 HydrophobicContact CD2-CD2 4.32Å; L200-W273 HydrophobicContact CD2-CG 3.81Å; E253-W273 HydrophobicContact CB-CD2 4.3Å; E253-W273 HydrophobicContact CB-CE3 3.5Å; E253-W273 VanDerWaalsContact CB-CE3 3.5Å; E253-W273 HydrophobicContact CB-CZ3 3.97Å; E253-W273 HydrophobicContact CG-CE3 3.9Å; E253-W273 HydrophobicContact CG-CZ3 4.02Å; Q254-W273 PolarHBondContact NE2-O 3.4Å; W273-P275 HydrophobicContact CE3-CG 4.35Å; W273-P275 HydrophobicContact CH2-CB 3.88Å; W273-P275 HydrophobicContact CH2-CG 3.7Å; W273-P275 HydrophobicContact CZ2-CB 4.1Å; W273-P275 HydrophobicContact CZ2-CG 4.28Å; W273-P275 HydrophobicContact CZ3-CB 4.41Å; W273-P275 HydrophobicContact CZ3-CG 3.73Å
274E84.5Confident75.7Confident161 Ų16199.7 Ų99.775%0.75256%0.558SS**  trans-108.2127.1170.9-71.9-176.3173.300108.9R272 S276R272-E274 PolarHBondContact O-N 2.79Å; E274-S276 PolarHBondContact O-N 3.49Å
275P77.9Confident73.9Confident81 Ų81100.8 Ų100.853%0.52657%0.57SS.*  trans-58.5127.7172.2-14.824.4000109.1W273 S277W273-P275 HydrophobicContact CE3-CG 4.35Å; W273-P275 HydrophobicContact CH2-CB 3.88Å; W273-P275 HydrophobicContact CH2-CG 3.7Å; W273-P275 HydrophobicContact CZ2-CB 4.1Å; W273-P275 HydrophobicContact CZ2-CG 4.28Å; W273-P275 HydrophobicContact CZ3-CB 4.41Å; W273-P275 HydrophobicContact CZ3-CG 3.73Å; P275-S277 PolarHBondContact O-N 3.3Å
276S62.8Low72.3Confident103 Ų103104.2 Ų104.272%0.7259%0.587SS**  trans-59.1114178.166.50000109.5E274 Q278E274-S276 PolarHBondContact O-N 3.49Å; S276-Q278 PolarHBondContact O-N 3.22Å
277S48.3Very low70.9Confident116 Ų116102.5 Ų102.581%0.81157%0.569SS**  trans-7665.316849.40000109.1P275 P279P275-S277 PolarHBondContact O-N 3.3Å; S277-P279 WeakPolarHBondContact O-CD 3.46Å
278Q45.7Very low69.5Low160 Ų16097 Ų9775%0.74856%0.555SS**  trans-66.6113.8156.8-80.3-169.3-20.200105.8S276 T280S276-Q278 PolarHBondContact O-N 3.22Å; Q278-T280 PolarHBondContact O-N 2.78Å
279P43.2Very low68.4Low105 Ų10595 Ų9568%0.68255%0.549SS*.  trans-60.6115.7168.225.2-29.3000105.3S277 I281S277-P279 WeakPolarHBondContact O-CD 3.46Å; P279-I281 PolarHBondContact O-N 3.12Å
280T50.4Low67.5Low135 Ų13597.6 Ų97.683%0.82856%0.563SS**  trans-61.786.5163.6-38.40000105.1Q278 P282Q278-T280 PolarHBondContact O-N 2.78Å; T280-P282 VanDerWaalsContact O-CD 3.26Å; T280-P282 WeakPolarHBondContact O-CD 3.43Å
281I52.5Low66.5Low104 Ų10498.5 Ų98.553%0.53357%0.568SS.*  trans-52.5117.9167.6-63.3175.3000103.3P279 I283 I286P279-I281 PolarHBondContact O-N 3.12Å; I281-I283 PolarHBondContact O-N 3.37Å; I281-I286 HydrophobicContact CG2-CD1 3.74Å
282P52.8Low65.5Low90 Ų90102.7 Ų102.758%0.58459%0.589SS**  trans-71.788.8-17628-31.6000106.6T280 V284 G285 I286T280-P282 VanDerWaalsContact O-CD 3.26Å; T280-P282 WeakPolarHBondContact O-CD 3.43Å; P282-V284 PolarHBondContact O-N 2.84Å; P282-G285 PolarHBondContact O-N 2.83Å; P282-I286 PolarHBondContact O-N 3.47Å
283I58.2Low64.6Low118 Ų118102.1 Ų102.161%0.60559%0.592SS**Hα-helixtrans-53-31.4177.6-65.2171.5000109.2I281 G285 I286 I287I281-I283 PolarHBondContact O-N 3.37Å; I283-G285 PolarHBondContact O-N 3.31Å; I283-I286 PolarHBondContact O-N 2.91Å; I283-I287 HydrophobicContact CG2-CD1 3.76Å; I283-I287 HydrophobicContact CG2-CG1 4.37Å; I283-I287 VanDerWaalsContact O-CG1 3.28Å; I283-I287 WeakPolarHBondContact O-CG1 3.34Å; I283-I287 PolarHBondContact O-N 3.14Å
284V55.3Low63.8Low117 Ų117101.9 Ų101.971%0.70960%0.603SS**Hα-helixtrans-62-39.6174.2-174.70000112.9P282 A288P282-V284 PolarHBondContact O-N 2.84Å; V284-A288 WeakPolarHBondContact O-CB 3.23Å; V284-A288 PolarHBondContact O-N 3.3Å
285G57Low63.5Low45 Ų4597.1 Ų97.146%0.46459%0.591SS.*Hα-helixtrans-69.6-36.2179.200000112.8P282 I283 G289P282-G285 PolarHBondContact O-N 2.83Å; I283-G285 PolarHBondContact O-N 3.31Å; G285-G289 PolarHBondContact O-N 2.88Å
286I64.2Low63.7Low96 Ų9698.3 Ų98.349%0.49260%0.597SS.*Hα-helixtrans-70.6-42.8176.1-61.5175.1000110.4I281 P282 I283 G289 L290I281-I286 HydrophobicContact CG2-CD1 3.74Å; P282-I286 PolarHBondContact O-N 3.47Å; I283-I286 PolarHBondContact O-N 2.91Å; I286-G289 PolarHBondContact O-N 3.08Å; I286-L290 HydrophobicContact CG2-CD1 3.93Å; I286-L290 HydrophobicContact CG2-CG 4.44Å; I286-L290 WeakPolarHBondContact O-CB 3.34Å; I286-L290 VanDerWaalsContact O-CG 3.31Å; I286-L290 WeakPolarHBondContact O-CG 3.46Å; I286-L290 PolarHBondContact O-N 3.34Å
287I65.8Low64.4Low98 Ų9897.6 Ų97.650%0.50358%0.584SS.*Hα-helixtrans-64.5-46.5177.2-66.9169.6000110.8I283 G289 L290 V291I283-I287 HydrophobicContact CG2-CD1 3.76Å; I283-I287 HydrophobicContact CG2-CG1 4.37Å; I283-I287 VanDerWaalsContact O-CG1 3.28Å; I283-I287 WeakPolarHBondContact O-CG1 3.34Å; I283-I287 PolarHBondContact O-N 3.14Å; I287-G289 VanDerWaalsContact C-N 3.32Å; I287-G289 PolarHBondContact O-N 2.9Å; I287-L290 PolarHBondContact O-N 2.86Å; I287-V291 HydrophobicContact CG2-CG2 4.32Å; I287-V291 VanDerWaalsContact O-CG2 3.28Å; I287-V291 WeakPolarHBondContact O-CG2 3.17Å; I287-V291 PolarHBondContact O-N 3.16Å
288A67.9Low65.7Low49 Ų4994.7 Ų94.741%0.40557%0.567SS.*Hα-helixtrans-60.9-41.817700000111.9V284 V291 L292V284-A288 WeakPolarHBondContact O-CB 3.23Å; V284-A288 PolarHBondContact O-N 3.3Å; A288-V291 PolarHBondContact O-N 2.91Å; A288-L292 WeakPolarHBondContact O-CB 3.44Å; A288-L292 WeakPolarHBondContact O-CG 3.33Å; A288-L292 PolarHBondContact O-N 3.12Å
289G73.1Confident67.2Low39 Ų3989 Ų8940%0.40255%0.552SS.*Hα-helixtrans-61.5-45.617500000112.9G285 I286 I287 L292 F293G285-G289 PolarHBondContact O-N 2.88Å; I286-G289 PolarHBondContact O-N 3.08Å; I287-G289 VanDerWaalsContact C-N 3.32Å; I287-G289 PolarHBondContact O-N 2.9Å; G289-L292 PolarHBondContact O-N 2.9Å; G289-F293 WeakPolarHBondContact O-CB 3.46Å; G289-F293 PolarHBondContact O-N 3.06Å
290L77.6Confident68.8Low119 Ų11986.9 Ų86.962%0.62354%0.543SS*.Hα-helixtrans-66.7-39178.5-74.5169.8000112.7I286 I287 F293 G294I286-L290 HydrophobicContact CG2-CD1 3.93Å; I286-L290 HydrophobicContact CG2-CG 4.44Å; I286-L290 WeakPolarHBondContact O-CB 3.34Å; I286-L290 VanDerWaalsContact O-CG 3.31Å; I286-L290 WeakPolarHBondContact O-CG 3.46Å; I286-L290 PolarHBondContact O-N 3.34Å; I287-L290 PolarHBondContact O-N 2.86Å; L290-F293 PolarHBondContact O-N 3.17Å; L290-G294 PolarHBondContact O-N 3.41Å
291V77.8Confident70.1Confident100 Ų10084.4 Ų84.461%0.60653%0.527SS*.Hα-helixtrans-65.1-44.9176.4171.40000110.7I287 A288 G294 A295I287-V291 HydrophobicContact CG2-CG2 4.32Å; I287-V291 VanDerWaalsContact O-CG2 3.28Å; I287-V291 WeakPolarHBondContact O-CG2 3.17Å; I287-V291 PolarHBondContact O-N 3.16Å; A288-V291 PolarHBondContact O-N 2.91Å; V291-G294 PolarHBondContact O-N 3.16Å; V291-A295 WeakPolarHBondContact O-CB 3.38Å; V291-A295 PolarHBondContact O-N 2.82Å
292L74.3Confident71.2Confident121 Ų12183.5 Ų83.563%0.63453%0.527SS*.Hα-helixtrans-62.4-44.6175.7-78.4166.4000111.5A288 G289 G294 A295 V296A288-L292 WeakPolarHBondContact O-CB 3.44Å; A288-L292 WeakPolarHBondContact O-CG 3.33Å; A288-L292 PolarHBondContact O-N 3.12Å; G289-L292 PolarHBondContact O-N 2.9Å; L292-G294 PolarHBondContact O-N 3.39Å; L292-A295 PolarHBondContact O-N 3.12Å; L292-V296 WeakPolarHBondContact O-CG2 3.33Å; L292-V296 PolarHBondContact O-N 2.83Å
293F74.5Confident72.2Confident143 Ų14382 Ų8263%0.62752%0.522SS*.Hα-helixtrans-64.3-42.4179.2-152.3-100000111.7G289 L290 V296 I297G289-F293 WeakPolarHBondContact O-CB 3.46Å; G289-F293 PolarHBondContact O-N 3.06Å; L290-F293 PolarHBondContact O-N 3.17Å; F293-V296 PolarHBondContact O-N 2.85Å; F293-I297 HydrophobicContact CD1-CD1 3.68Å; F293-I297 HydrophobicContact CD1-CG1 4.37Å; F293-I297 HydrophobicContact CE1-CD1 3.66Å; F293-I297 HydrophobicContact CE1-CG1 4.42Å; F293-I297 WeakPolarHBondContact O-CG1 3.49Å; F293-I297 PolarHBondContact O-N 3.31Å
294G76.8Confident72.9Confident40 Ų4079.1 Ų79.141%0.41252%0.515SS..Hα-helixtrans-61.3-42.5174.200000112.9L290 V291 L292 I297 A298L290-G294 PolarHBondContact O-N 3.41Å; V291-G294 PolarHBondContact O-N 3.16Å; L292-G294 PolarHBondContact O-N 3.39Å; G294-I297 PolarHBondContact O-N 3.05Å; G294-A298 WeakPolarHBondContact O-CB 3.01Å; G294-A298 PolarHBondContact O-N 3.34Å
295A78.1Confident73.8Confident61 Ų6177.3 Ų77.350%0.50450%0.504SS..Hα-helixtrans-64.7-40177.300000112.5V291 L292 A298 G299V291-A295 WeakPolarHBondContact O-CB 3.38Å; V291-A295 PolarHBondContact O-N 2.82Å; L292-A295 PolarHBondContact O-N 3.12Å; A295-A298 PolarHBondContact O-N 2.72Å; A295-G299 PolarHBondContact O-N 3.42Å
296V80.9Confident74.6Confident105 Ų10581.5 Ų81.564%0.63651%0.513SS*.Hα-helixtrans-64.7-45176.3172.30000111L292 F293 G299 A300L292-V296 WeakPolarHBondContact O-CG2 3.33Å; L292-V296 PolarHBondContact O-N 2.83Å; F293-V296 PolarHBondContact O-N 2.85Å; V296-G299 PolarHBondContact O-N 3.02Å; V296-A300 WeakPolarHBondContact O-CB 3.37Å; V296-A300 PolarHBondContact O-N 3.02Å
297I77.8Confident74.9Confident88 Ų8886.6 Ų86.645%0.45153%0.527SS..Hα-helixtrans-63.3-46.8177.5-68.1176.7000110.5F293 G294 G299 A300 V301F293-I297 HydrophobicContact CD1-CD1 3.68Å; F293-I297 HydrophobicContact CD1-CG1 4.37Å; F293-I297 HydrophobicContact CE1-CD1 3.66Å; F293-I297 HydrophobicContact CE1-CG1 4.42Å; F293-I297 WeakPolarHBondContact O-CG1 3.49Å; F293-I297 PolarHBondContact O-N 3.31Å; G294-I297 PolarHBondContact O-N 3.05Å; I297-G299 VanDerWaalsContact C-N 3.33Å; I297-G299 PolarHBondContact O-N 3.36Å; I297-A300 PolarHBondContact O-N 3Å; I297-V301 HydrophobicContact CG2-CG2 4.33Å; I297-V301 VanDerWaalsContact O-CG2 3.3Å; I297-V301 WeakPolarHBondContact O-CG2 3.33Å; I297-V301 PolarHBondContact O-N 2.77Å
298A75.8Confident74.9Confident55 Ų5591.4 Ų91.446%0.45554%0.538SS..Hα-helixtrans-59.9-44.5177.800000111.5G294 A295 A300 V301 V302G294-A298 WeakPolarHBondContact O-CB 3.01Å; G294-A298 PolarHBondContact O-N 3.34Å; A295-A298 PolarHBondContact O-N 2.72Å; A298-A300 PolarHBondContact O-N 2.98Å; A298-V301 PolarHBondContact O-N 3.38Å; A298-V302 VanDerWaalsContact O-CG2 3.29Å; A298-V302 WeakPolarHBondContact O-CG2 3.13Å; A298-V302 PolarHBondContact O-N 3.05Å
299G77.1Confident74.5Confident42 Ų4298.4 Ų98.443%0.43355%0.554SS.*Hα-helixtrans-60.4-44.4175.300000112.9A295 V296 I297 V302 A303A295-G299 PolarHBondContact O-N 3.42Å; V296-G299 PolarHBondContact O-N 3.02Å; I297-G299 VanDerWaalsContact C-N 3.33Å; I297-G299 PolarHBondContact O-N 3.36Å; G299-V302 PolarHBondContact O-N 3.03Å; G299-A303 WeakPolarHBondContact O-CB 3.38Å; G299-A303 PolarHBondContact O-N 2.92Å
300A77.4Confident73.6Confident59 Ų59105 Ų10549%0.48857%0.572SS.*Hα-helixtrans-64.5-40.9177.700000112.4V296 I297 A298 A303 A304V296-A300 WeakPolarHBondContact O-CB 3.37Å; V296-A300 PolarHBondContact O-N 3.02Å; I297-A300 PolarHBondContact O-N 3Å; A298-A300 PolarHBondContact O-N 2.98Å; A300-A303 PolarHBondContact O-N 3.22Å; A300-A304 WeakPolarHBondContact O-CB 3.25Å; A300-A304 PolarHBondContact O-N 3.37Å
301V77.4Confident72.4Confident83 Ų83102.7 Ų102.750%0.50357%0.566SS.*Hα-helixtrans-65.2-45.1176.5172.30000110.8I297 A298 A303 A304 V305I297-V301 HydrophobicContact CG2-CG2 4.33Å; I297-V301 VanDerWaalsContact O-CG2 3.3Å; I297-V301 WeakPolarHBondContact O-CG2 3.33Å; I297-V301 PolarHBondContact O-N 2.77Å; A298-V301 PolarHBondContact O-N 3.38Å; V301-A303 PolarHBondContact O-N 2.83Å; V301-A304 PolarHBondContact O-N 3.24Å; V301-V305 HydrophobicContact CG1-CG2 4.34Å; V301-V305 WeakPolarHBondContact O-CB 3.48Å; V301-V305 VanDerWaalsContact O-CG2 3.28Å; V301-V305 WeakPolarHBondContact O-CG2 3.37Å; V301-V305 PolarHBondContact O-N 3.2Å
302V76.3Confident71.2Confident86 Ų86102.1 Ų102.152%0.52157%0.566SS.*Hα-helixtrans-61.2-45.1176.8172.20000110.8A298 G299 A304 V305 M306A298-V302 VanDerWaalsContact O-CG2 3.29Å; A298-V302 WeakPolarHBondContact O-CG2 3.13Å; A298-V302 PolarHBondContact O-N 3.05Å; G299-V302 PolarHBondContact O-N 3.03Å; V302-A304 PolarHBondContact O-N 2.97Å; V302-V305 PolarHBondContact O-N 2.7Å; V302-M306 HydrophobicContact CG1-SD 4.2Å; V302-M306 WeakPolarHBondContact O-CB 3.5Å; V302-M306 WeakPolarHBondContact O-CG 3.47Å; V302-M306 PolarHBondContact O-N 3.12Å
303A72.7Confident69.9Low58 Ų58103.9 Ų103.948%0.47958%0.576SS.*Hα-helixtrans-61.4-43.6176.500000112.2G299 A300 V301 M306 W307G299-A303 WeakPolarHBondContact O-CB 3.38Å; G299-A303 PolarHBondContact O-N 2.92Å; A300-A303 PolarHBondContact O-N 3.22Å; V301-A303 PolarHBondContact O-N 2.83Å; A303-M306 PolarHBondContact O-N 3.44Å; A303-W307 WeakPolarHBondContact O-CB 3.24Å; A303-W307 PolarHBondContact O-N 3.43Å
304A74.1Confident68.5Low57 Ų57107.2 Ų107.247%0.47159%0.585SS.*Hα-helixtrans-65.4-39.7177.400000112.6A300 V301 V302 W307 R308A300-A304 WeakPolarHBondContact O-CB 3.25Å; A300-A304 PolarHBondContact O-N 3.37Å; V301-A304 PolarHBondContact O-N 3.24Å; V302-A304 PolarHBondContact O-N 2.97Å; A304-W307 PolarHBondContact O-N 3.29Å; A304-R308 WeakPolarHBondContact O-CB 3.41Å; A304-R308 PolarHBondContact O-N 3.08Å
305V73.1Confident66.6Low80 Ų80115 Ų11549%0.48561%0.607SS.*Hα-helixtrans-67.1-42.4176.1170.70000111V301 V302 W307 R308 R309V301-V305 HydrophobicContact CG1-CG2 4.34Å; V301-V305 WeakPolarHBondContact O-CB 3.48Å; V301-V305 VanDerWaalsContact O-CG2 3.28Å; V301-V305 WeakPolarHBondContact O-CG2 3.37Å; V301-V305 PolarHBondContact O-N 3.2Å; V302-V305 PolarHBondContact O-N 2.7Å; V305-W307 VanDerWaalsContact C-N 3.33Å; V305-W307 PolarHBondContact O-N 3.07Å; V305-R308 PolarHBondContact O-N 3.19Å; V305-R309 PolarHBondContact O-N 2.85Å
306M73.3Confident64.5Low132 Ų132116 Ų11665%0.6562%0.624SS**Hα-helixtrans-63.3-39.4174.3-73.3-176.16800111.9V302 A303 R309 K310V302-M306 HydrophobicContact CG1-SD 4.2Å; V302-M306 WeakPolarHBondContact O-CB 3.5Å; V302-M306 WeakPolarHBondContact O-CG 3.47Å; V302-M306 PolarHBondContact O-N 3.12Å; A303-M306 PolarHBondContact O-N 3.44Å; M306-R309 PolarHBondContact O-N 3.41Å; M306-K310 WeakPolarHBondContact O-CB 3.4Å; M306-K310 PolarHBondContact O-N 2.81Å
307W71.1Confident62.2Low204 Ų204114.8 Ų114.877%0.77363%0.633SS**Hα-helixtrans-64.3-43.7174.9-159.9-62000111.7A303 A304 V305 K310 S311A303-W307 WeakPolarHBondContact O-CB 3.24Å; A303-W307 PolarHBondContact O-N 3.43Å; A304-W307 PolarHBondContact O-N 3.29Å; V305-W307 VanDerWaalsContact C-N 3.33Å; V305-W307 PolarHBondContact O-N 3.07Å; W307-K310 PolarHBondContact O-N 3.26Å; W307-S311 PolarHBondContact O-N 3.05Å; W307-S311 PolarHBondContact O-OG 3.31Å
308R65.8Low60Low198 Ų198115.9 Ų115.975%0.74765%0.648SS**Hα-helixtrans-63.3-41.1175.3-94.5-173.7174.5176.4-0.4112.7A304 V305 K310 S311 S312A304-R308 WeakPolarHBondContact O-CB 3.41Å; A304-R308 PolarHBondContact O-N 3.08Å; V305-R308 PolarHBondContact O-N 3.19Å; R308-K310 VanDerWaalsContact C-N 3.3Å; R308-K310 PolarHBondContact O-N 3.5Å; R308-S311 PolarHBondContact O-N 2.97Å; R308-S311 PolarHBondContact O-OG 3.37Å; R308-S311 VanDerWaalsContact O-OG 3.14Å; R308-S312 WeakPolarHBondContact O-CB 3.41Å; R308-S312 PolarHBondContact O-N 3.16Å; R308-S312 PolarHBondContact O-OG 3.48Å
309R59.4Low57.9Low197 Ų197123.2 Ų123.274%0.74367%0.665SS**Hα-helixtrans-63.3-36.6174.5-103.3-176.7165.8177.3-3.7112V305 M306 S312V305-R309 PolarHBondContact O-N 2.85Å; M306-R309 PolarHBondContact O-N 3.41Å; R309-S312 PolarHBondContact O-OG 3.34Å; R309-S312 VanDerWaalsContact O-OG 3.12Å
310K54.3Low55.8Low177 Ų177126 Ų12677%0.7768%0.678SS**Hα-helixtrans-75-25.5177.3-164.5173.3-179.5179.30113.2M306 W307 R308M306-K310 WeakPolarHBondContact O-CB 3.4Å; M306-K310 PolarHBondContact O-N 2.81Å; W307-K310 PolarHBondContact O-N 3.26Å; R308-K310 VanDerWaalsContact C-N 3.3Å; R308-K310 PolarHBondContact O-N 3.5Å
311S53.3Low53.7Low70 Ų70131.7 Ų131.749%0.4970%0.695SS.*Hα-helixtrans-89.2-21.717666.90000114W307 R308W307-S311 PolarHBondContact O-N 3.05Å; W307-S311 PolarHBondContact O-OG 3.31Å; R308-S311 PolarHBondContact O-N 2.97Å; R308-S311 PolarHBondContact O-OG 3.37Å; R308-S311 VanDerWaalsContact O-OG 3.14Å
312S52.8Low51.5Low89 Ų89132.4 Ų132.462%0.62271%0.709SS**Hα-helixtrans-78-15.6176.958.30000114.5R308 R309 R314R308-S312 WeakPolarHBondContact O-CB 3.41Å; R308-S312 PolarHBondContact O-N 3.16Å; R308-S312 PolarHBondContact O-OG 3.48Å; R309-S312 PolarHBondContact O-OG 3.34Å; R309-S312 VanDerWaalsContact O-OG 3.12Å; S312-R314 VanDerWaalsContact C-N 3.26Å; S312-R314 PolarHBondContact O-N 3.39Å
313D45.6Very low49.3Very low157 Ų157132.6 Ų132.684%0.8472%0.72SS**THydrogen-bonded Turntrans-81.92.8174.6-104.7-6.2000113.8
314R44.8Very low47.4Very low213 Ų213135.4 Ų135.480%0.80474%0.736SS**SBendtrans-139.563.2-173.7-155.6176.3-174.91681.2113.3S312S312-R314 VanDerWaalsContact C-N 3.26Å; S312-R314 PolarHBondContact O-N 3.39Å
315K38.1Very low45.6Very low203 Ų203138.2 Ų138.288%0.88375%0.752SS**  trans157.696.4139.4-90170.3174.8-177.90110.6
316G33.9Very low43.7Very low84 Ų84141.6 Ų141.687%0.86677%0.767SS**  trans-88.7135.3158.500000111
317G32.3Very low42.2Very low79 Ų79141.2 Ų141.281%0.81478%0.777SS**  trans89.8113.4146.700000118.8
318S31.8Very low40.6Very low110 Ų110135.6 Ų135.677%0.76978%0.775SS**  175115.8117.8-176.60000113.5
319Y32.2Very low39.4Very low210 Ų210135.8 Ų135.882%0.82478%0.784SS**  trans37.5120.1139.7-79.3-90000124.7
320S33.1Very low38.1Very low99 Ų99129.4 Ų129.469%0.69278%0.78SS**  42144.8127.7620000120.5
321Q32.7Very low37.4Very low180 Ų180126 Ų12684%0.84178%0.778SS**  cis-176.5150.439-172172.7-3.600111
322A30.8Very low36.8Very low97 Ų97129.1 Ų129.180%0.80279%0.79SS**  trans53.8153.1157.400000119.9
323A31.3Very low36Very low91 Ų91132.4 Ų132.475%0.75280%0.797SS**  cis-157.714525.300000109.8
324S31.5Very low35.6Very low116 Ų116129.3 Ų129.381%0.81179%0.787SS**  49.9113.2112.2168.40000118
325S35.7Very low35.4Very low116 Ų116126 Ų12681%0.81179%0.785SS**  -172.5135.1118.256.60000112.6
326D33.7Very low35.5Very low152 Ų152121.9 Ų121.981%0.81378%0.777SS**  trans-51.2151.1171.1-74.7-56.1000116
327S41.6Very low35.7Very low123 Ų123121.9 Ų121.986%0.8677%0.769SS**  -171.599121.718.30000111.6
328A37.2Very low35.9Very low87 Ų87124 Ų12472%0.71977%0.769SS**  trans10.5152.4136.600000123.2
329Q40.6Very low36.3Very low201 Ų201128.2 Ų128.294%0.93977%0.774SS**  trans83.7123.2153-74170.7-13.800117.6
330G33.9Very low36.8Very low63 Ų63128.4 Ų128.465%0.64980%0.797SS**  cis-168.6143.75.500000111.6
331S38.9Very low37Very low106 Ų106129.9 Ų129.974%0.74180%0.802SS**  6.9142127.939.90000117
332D39.8Very low37.3Very low136 Ų136127.3 Ų127.373%0.72780%0.8SS**  cis-161.4134.633.2-109.3-22.3000108.9
333M36.9Very low37.6Very low158 Ų158128.9 Ų128.978%0.77880%0.8SS**  67.5109.691.8-82.7-133.5-177.600113.1
334S36.8Very low38Very low91 Ų91131.2 Ų131.264%0.63680%0.803SS**  105.9141.788.5-780000107.7
335L40.8Very low38.4Very low143 Ų143132.1 Ų132.175%0.74980%0.802SS**  cis-174.9150.331.4-125.7161.6000107.1
336T40.5Very low38.6Very low118 Ų118133.2 Ų133.272%0.72480%0.802SS**  trans53.8122.6147.231.40000119.9
337A36.8Very low38.9Very low84 Ų84131.9 Ų131.969%0.69480%0.801SS**  cis108151.646.900000111.9
338C37.4Very low38.7Very low122 Ų122132.5 Ų132.582%0.82480%0.796SS**  trans78.6106.8171.2-63.30000115.2
339K40.3Very low38.8Very low199 Ų199136.3 Ų136.387%0.86580%0.803SS**  67.191.564.2-159.9-177.4-166.2179.40111.7
340V43.3Very low38.7Very low215 Ų215130.5 Ų130.5100%1.30379%0.79SS**  -139.40113175.90000107

Retrieved 340 of 340 residues in 1519.2 ms (Link to these results)