A0A060VN81_ONCMY Loading...

Y+L amino acid transporter 2

AlphaFold DB , UniProt , Accession A0A060VN81, Species ONCMY (Oncorhynchus mykiss, Rainbow trout), Gene LOC110530061, Length 510 aa.

Structure Viewer

Loading PAE data...

(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	45.5	Very low	38	Very low	208 Å²	208	147 Å²	147	100%	1.025	74%	0.741	S	S	*	*				0	-43.1	0	-140.1	171.9	-142.3	0	0	112.4
2	R	38.7	Very low	37.5	Very low	234 Å²	234	147.8 Å²	147.8	88%	0.883	75%	0.747	S	S	*	*	H	α-helix	trans	-64.9	-31.3	169.6	-87.7	-179.9	171.7	174.5	-3.2	114.9
3	E	39	Very low	37	Very low	170 Å²	170	145.7 Å²	145.7	79%	0.794	75%	0.752	S	S	*	*	H	α-helix	trans	-74.9	-28.4	176.4	-75.7	177.5	147.2	0	0	114.4	L5 A6 A7	E3-L5 VanDerWaalsContact C-N 3.3Å; E3-L5 PolarHBondContact O-N 3.44Å; E3-A6 PolarHBondContact O-N 2.94Å; E3-A7 PolarHBondContact O-N 3.28Å
4	K	38.3	Very low	36.5	Very low	182 Å²	182	144.8 Å²	144.8	79%	0.791	76%	0.76	S	S	*	*	H	α-helix	trans	-72.4	-23.3	175.3	-82.8	-172.3	173.7	-175.6	0	112.8
5	L	39.8	Very low	36.7	Very low	135 Å²	135	140.5 Å²	140.5	71%	0.707	77%	0.765	S	S	*	*	H	α-helix	trans	-79.8	-29.1	175	-91.3	149.7	0	0	0	112.8	E3	E3-L5 VanDerWaalsContact C-N 3.3Å; E3-L5 PolarHBondContact O-N 3.44Å
6	A	39.1	Very low	36.2	Very low	53 Å²	53	139.4 Å²	139.4	44%	0.438	77%	0.771	S	S	.	*	H	α-helix	trans	-76.2	-27.3	175.4	0	0	0	0	0	113.2	E3 M8	E3-A6 PolarHBondContact O-N 2.94Å; A6-M8 VanDerWaalsContact C-N 3.35Å
7	A	35.2	Very low	36.2	Very low	71 Å²	71	142.6 Å²	142.6	59%	0.587	78%	0.779	S	S	*	*	H	α-helix	trans	-73.6	-24.3	177.7	0	0	0	0	0	113.4	E3	E3-A7 PolarHBondContact O-N 3.28Å
8	M	34.6	Very low	35.7	Very low	155 Å²	155	139.9 Å²	139.9	76%	0.764	78%	0.779	S	S	*	*	H	α-helix	trans	-83.2	-17.7	-179.4	-128.7	176.1	138.9	0	0	113.3	A6 R10	A6-M8 VanDerWaalsContact C-N 3.35Å; M8-R10 VanDerWaalsContact C-N 3.31Å; M8-R10 PolarHBondContact O-N 2.56Å
9	S	35.4	Very low	35.1	Very low	101 Å²	101	142.4 Å²	142.4	71%	0.706	78%	0.784	S	S	*	*	T	Hydrogen-bonded Turn	trans	-83.3	-3.4	177.7	96.2	0	0	0	0	113.9
10	R	36.9	Very low	35.2	Very low	218 Å²	218	140.8 Å²	140.8	82%	0.823	79%	0.79	S	S	*	*	T	Hydrogen-bonded Turn	trans	-105.5	1.5	-176.8	-68.8	-171.5	-166.6	176.2	4.3	114.9	M8	M8-R10 VanDerWaalsContact C-N 3.31Å; M8-R10 PolarHBondContact O-N 2.56Å
11	S	35.1	Very low	34.9	Very low	90 Å²	90	139.5 Å²	139.5	63%	0.629	79%	0.79	S	S	*	*	S	Bend	trans	-103.7	8.6	-174.9	76.2	0	0	0	0	116
12	L	32.7	Very low	34.4	Very low	157 Å²	157	137.5 Å²	137.5	82%	0.822	78%	0.784	S	S	*	*	S	Bend	trans	-132.1	62.4	-178.6	-83.7	154.3	0	0	0	111
13	C	30.3	Very low	34.1	Very low	120 Å²	120	133.8 Å²	133.8	81%	0.811	78%	0.782	S	S	*	*			trans	166.5	118	138.9	-90.2	0	0	0	0	109.5
14	P	29.8	Very low	33.6	Very low	133 Å²	133	133.9 Å²	133.9	86%	0.864	79%	0.787	S	S	*	*			trans	-73.7	140.3	171	18.5	-8	0	0	0	110.1
15	G	39.9	Very low	33.2	Very low	81 Å²	81	134.2 Å²	134.2	84%	0.835	79%	0.788	S	S	*	*			trans	-76.8	148.6	168.2	0	0	0	0	0	111.8
16	S	28.9	Very low	32.8	Very low	123 Å²	123	133.3 Å²	133.3	86%	0.86	79%	0.788	S	S	*	*			trans	-141.8	119.5	159.1	175.9	0	0	0	0	107.6
17	Q	36.8	Very low	32.4	Very low	193 Å²	193	136.6 Å²	136.6	90%	0.902	81%	0.805	S	S	*	*			trans	-67.5	145.9	178.9	-65.1	169.3	-38	0	0	111.4
18	A	25.9	Very low	32.2	Very low	94 Å²	94	140.7 Å²	140.7	78%	0.777	82%	0.817	S	S	*	*			trans	-162.8	117.5	141.2	0	0	0	0	0	112
19	E	25.1	Very low	32.2	Very low	187 Å²	187	137.5 Å²	137.5	87%	0.874	82%	0.824	S	S	*	*			trans	62.6	116.9	147.7	-65.1	-179.2	168.9	0	0	122.1	S21	E19-S21 PolarHBondContact O-N 3.42Å
20	A	38	Very low	31.8	Very low	111 Å²	111	135.4 Å²	135.4	92%	0.917	82%	0.819	S	S	*	*			trans	-62.3	122.3	162.7	0	0	0	0	0	110.4
21	S	27.3	Very low	31.7	Very low	113 Å²	113	133.4 Å²	133.4	79%	0.79	82%	0.819	S	S	*	*			trans	-122.5	127.1	156.2	43.1	0	0	0	0	108	E19 D23	E19-S21 PolarHBondContact O-N 3.42Å; S21-D23 PolarHBondContact O-N 3.35Å; S21-D23 VanDerWaalsContact O-N 3.15Å
22	D	36.4	Very low	31.6	Very low	166 Å²	166	138.2 Å²	138.2	89%	0.888	83%	0.831	S	S	*	*	S	Bend	trans	-53	108.1	169.7	-100.1	-32.8	0	0	0	109.6
23	D	31.4	Very low	31.8	Very low	156 Å²	156	138 Å²	138	83%	0.834	82%	0.824	S	S	*	*			trans	-176.8	59	151.9	-97.2	-27	0	0	0	110.6	S21 K25	S21-D23 PolarHBondContact O-N 3.35Å; S21-D23 VanDerWaalsContact O-N 3.15Å; D23-K25 VanDerWaalsContact C-N 3.33Å; D23-K25 PolarHBondContact O-N 2.96Å; D23-K25 VanDerWaalsContact O-N 3.17Å
24	L	28.8	Very low	32.2	Very low	173 Å²	173	141.9 Å²	141.9	91%	0.906	83%	0.833	S	S	*	*			trans	-84.9	80	166.8	-104.6	143.4	0	0	0	109.3	T26	L24-T26 PolarHBondContact O-N 3.19Å
25	K	30.9	Very low	33.1	Very low	188 Å²	188	142.8 Å²	142.8	82%	0.817	83%	0.825	S	S	*	*			trans	-64.7	116.6	152.5	-82.2	179.6	-179.8	171.7	0	107.3	D23	D23-K25 VanDerWaalsContact C-N 3.33Å; D23-K25 PolarHBondContact O-N 2.96Å; D23-K25 VanDerWaalsContact O-N 3.17Å
26	T	29.5	Very low	33.7	Very low	116 Å²	116	143.8 Å²	143.8	71%	0.712	81%	0.809	S	S	*	*			trans	-41.3	127	167.2	44.1	0	0	0	0	110.5	L24 N28	L24-T26 PolarHBondContact O-N 3.19Å; T26-N28 PolarHBondContact O-N 3.5Å; T26-N28 VanDerWaalsContact O-N 3.1Å
27	P	31.7	Very low	35.6	Very low	122 Å²	122	145.4 Å²	145.4	79%	0.792	80%	0.801	S	S	*	*			trans	-66.8	116.2	169.7	24.7	-24.6	0	0	0	107	G29	P27-G29 PolarHBondContact O-N 2.69Å
28	N	31.1	Very low	37.6	Very low	157 Å²	157	143.5 Å²	143.5	84%	0.84	79%	0.786	S	S	*	*			trans	-50.8	124.7	167.1	-95.3	-14.6	0	0	0	108.1	T26 G30	T26-N28 PolarHBondContact O-N 3.5Å; T26-N28 VanDerWaalsContact O-N 3.1Å; N28-G30 PolarHBondContact O-N 3.28Å
29	G	33.6	Very low	40.1	Very low	88 Å²	88	145.1 Å²	145.1	91%	0.907	78%	0.777	S	S	*	*			trans	-66.6	76	168.9	0	0	0	0	0	110.6	P27	P27-G29 PolarHBondContact O-N 2.69Å
30	G	28.7	Very low	42.7	Very low	58 Å²	58	137.3 Å²	137.3	60%	0.598	74%	0.741	S	S	*	*			trans	-86.6	116.5	160.3	0	0	0	0	0	107.6	N28 E32	N28-G30 PolarHBondContact O-N 3.28Å; G30-E32 PolarHBondContact O-N 3.23Å
31	E	33	Very low	45.1	Very low	176 Å²	176	133.5 Å²	133.5	82%	0.822	71%	0.707	S	S	*	*			trans	-51.4	108.9	158.6	-69.9	173.4	159.9	0	0	107.4	K33	E31-K33 PolarHBondContact O-N 3.11Å
32	E	33.2	Very low	48	Very low	191 Å²	191	130 Å²	130	89%	0.893	68%	0.68	S	S	*	*			trans	-66.4	90.2	171.5	-81.2	-168.9	159.4	0	0	107.7	G30 M34	G30-E32 PolarHBondContact O-N 3.23Å; E32-M34 PolarHBondContact O-N 2.88Å; E32-M34 VanDerWaalsContact O-N 3.12Å
33	K	37.8	Very low	50.3	Low	152 Å²	152	126.2 Å²	126.2	66%	0.661	66%	0.664	S	S	*	*			trans	-56.5	116.7	170.1	-65.3	-174.9	177.6	-170.4	0	107.7	E31 Q35	E31-K33 PolarHBondContact O-N 3.11Å; K33-Q35 VanDerWaalsContact C-N 3.28Å; K33-Q35 HydrophobicContact CB-CG 4.19Å; K33-Q35 PolarHBondContact O-N 3.23Å
34	M	39.3	Very low	52.7	Low	202 Å²	202	123 Å²	123	100%	0.995	65%	0.647	S	S	*	*			trans	-65.1	91.5	167.9	-94.8	-167.8	179.4	0	0	108.6	E32	E32-M34 PolarHBondContact O-N 2.88Å; E32-M34 VanDerWaalsContact O-N 3.12Å
35	Q	47.2	Very low	55.3	Low	151 Å²	151	115 Å²	115	71%	0.706	61%	0.606	S	S	*	*	P	Polyproline II helix	trans	-93.2	144	172.1	-66.9	-174.3	-6.3	0	0	110	K33 K37	K33-Q35 VanDerWaalsContact C-N 3.28Å; K33-Q35 HydrophobicContact CB-CG 4.19Å; K33-Q35 PolarHBondContact O-N 3.23Å; Q35-K37 PolarHBondContact O-N 2.67Å
36	M	54	Low	58	Low	103 Å²	103	107.7 Å²	107.7	51%	0.507	58%	0.576	S	S	.	*	P	Polyproline II helix	trans	-58	133.7	172.1	-68	-68.6	-78.5	0	0	109.9	E254	M36-E254 HydrophobicContact CB-CG 4.27Å; M36-E254 HydrophobicContact CE-CG 3.83Å; M36-E254 VanDerWaalsContact CE-OE1 3.24Å; M36-E254 WeakPolarHBondContact CE-OE1 3.24Å
37	K	68.3	Low	60.5	Low	157 Å²	157	104.9 Å²	104.9	68%	0.683	56%	0.56	S	S	*	*	P	Polyproline II helix	trans	-70.2	133.6	179.2	-68.6	-174.7	178.7	-178.9	0	110.2	Q35 E39	Q35-K37 PolarHBondContact O-N 2.67Å; K37-E39 HydrophobicContact CB-CG 3.86Å; K37-E39 WeakPolarHBondContact CD-OE1 3.49Å; K37-E39 PolarHBondContact O-N 2.89Å; K37-E39 VanDerWaalsContact O-N 3.09Å
38	R	77.4	Confident	62.8	Low	153 Å²	153	101.2 Å²	101.2	58%	0.577	53%	0.533	S	S	*	.			trans	-80.1	85.7	176.4	-67.1	-177.6	-178.5	-179.7	-0.2	111	E253 E254 Q256	R38-E253 WeakPolarHBondContact CG-O 3.46Å; R38-E254 CarbonylContact C-O 3.18Å; R38-E254 WeakPolarHBondContact CA-O 3.44Å; R38-Q256 HydrophobicContact CB-CG 4.31Å; R38-Q256 VanDerWaalsContact O-CG 3.23Å; R38-Q256 WeakPolarHBondContact O-CG 3.39Å; R38-Q256 PolarHBondContact O-NE2 3.2Å
39	E	78.9	Confident	65.4	Low	128 Å²	128	93.8 Å²	93.8	60%	0.598	49%	0.493	S	S	*	.			trans	-109.9	-15.5	-174	-64	-175.6	173.9	0	0	113.5	K37 S41 E254	K37-E39 HydrophobicContact CB-CG 3.86Å; K37-E39 WeakPolarHBondContact CD-OE1 3.49Å; K37-E39 PolarHBondContact O-N 2.89Å; K37-E39 VanDerWaalsContact O-N 3.09Å; E39-S41 PolarHBondContact O-N 3.48Å; E39-E254 PolarHBondContact N-O 3.13Å
40	I	80.8	Confident	67.9	Low	22 Å²	22	90.2 Å²	90.2	11%	0.113	45%	0.454	C	S	.	.	B	Isolated β-bridge	trans	-82.7	105.6	-177.1	-55.2	178.6	0	0	0	110	N44 V251 E254 I255 Q256	I40-N44 HydrophobicContact CG2-CB 4.1Å; I40-V251 HydrophobicContact CD1-CB 4.03Å; I40-V251 HydrophobicContact CD1-CG2 3.78Å; I40-E254 HydrophobicContact CD1-CB 3.74Å; I40-E254 HydrophobicContact CG1-CB 4.09Å; I40-E254 PolarHBondContact N-O 2.75Å; I40-I255 HydrophobicContact CB-CG1 4.23Å; I40-I255 HydrophobicContact CG2-CG1 4.27Å; I40-Q256 PolarHBondContact O-N 3.17Å
41	S	87.9	Confident	70.3	Confident	31 Å²	31	87.7 Å²	87.7	22%	0.217	43%	0.428	C	S	.	.			trans	-77.5	167.8	173.6	70.8	0	0	0	0	112.6	E39 N44 G45	E39-S41 PolarHBondContact O-N 3.48Å; S41-N44 WeakPolarHBondContact O-CB 3.49Å; S41-N44 PolarHBondContact O-N 3.22Å; S41-N44 PolarHBondContact OG-ND2 3.18Å; S41-N44 VanDerWaalsContact OG-ND2 3.15Å; S41-N44 PolarHBondContact OG-OD1 3.42Å; S41-G45 PolarHBondContact O-N 2.97Å
42	L	87.2	Confident	72.5	Confident	40 Å²	40	81.4 Å²	81.4	21%	0.209	40%	0.4	C	S	.	.	H	α-helix	trans	-57.6	-48	178.7	173.9	64.7	0	0	0	113.7	N44 G45 I46 N261 L264 A265	L42-N44 VanDerWaalsContact C-N 3.3Å; L42-N44 PolarHBondContact O-N 3.12Å; L42-G45 PolarHBondContact O-N 3.12Å; L42-G45 VanDerWaalsContact O-N 3.13Å; L42-I46 HydrophobicContact CD1-CD1 4.22Å; L42-I46 HydrophobicContact CD1-CG1 4.35Å; L42-I46 HydrophobicContact CG-CD1 4.2Å; L42-I46 WeakPolarHBondContact O-CG1 3.39Å; L42-I46 PolarHBondContact O-N 3.41Å; L42-N261 HydrophobicContact CB-CB 4.32Å; L42-N261 HydrophobicContact CD1-CB 4.35Å; L42-N261 WeakPolarHBondContact CD1-O 3.27Å; L42-L264 HydrophobicContact CD1-CB 3.83Å; L42-L264 HydrophobicContact CD2-CB 4.4Å; L42-L264 HydrophobicContact CD2-CD1 4.29Å; L42-A265 HydrophobicContact CD1-CB 3.98Å
43	P	85.4	Confident	75	Confident	87 Å²	87	72.5 Å²	72.5	57%	0.565	36%	0.358	S	S	*	.	H	α-helix	trans	-60.6	-39	175.5	-23.8	34.5	0	0	0	112.8	G45 I46 C47	P43-G45 VanDerWaalsContact C-N 3.3Å; P43-G45 PolarHBondContact O-N 3.35Å; P43-I46 PolarHBondContact O-N 2.72Å; P43-C47 WeakPolarHBondContact O-CB 3.46Å; P43-C47 PolarHBondContact O-N 2.87Å
44	N	81.9	Confident	77.2	Confident	89 Å²	89	65.2 Å²	65.2	48%	0.476	33%	0.327	S	S	.	.	H	α-helix	trans	-62.8	-40.8	175.4	-62.9	-6.7	0	0	0	110.3	I40 S41 L42 C47 L48	I40-N44 HydrophobicContact CG2-CB 4.1Å; S41-N44 WeakPolarHBondContact O-CB 3.49Å; S41-N44 PolarHBondContact O-N 3.22Å; S41-N44 PolarHBondContact OG-ND2 3.18Å; S41-N44 VanDerWaalsContact OG-ND2 3.15Å; S41-N44 PolarHBondContact OG-OD1 3.42Å; L42-N44 VanDerWaalsContact C-N 3.3Å; L42-N44 PolarHBondContact O-N 3.12Å; N44-C47 PolarHBondContact O-N 3.44Å; N44-L48 VanDerWaalsContact O-CB 3.26Å; N44-L48 WeakPolarHBondContact O-CB 3.45Å; N44-L48 PolarHBondContact O-N 2.82Å
45	G	83.3	Confident	79.1	Confident	3 Å²	3	56 Å²	56	3%	0.031	28%	0.284	C	S	.	.	H	α-helix	trans	-62.8	-43.9	176	0	0	0	0	0	113.4	S41 L42 P43 L48 I49	S41-G45 PolarHBondContact O-N 2.97Å; L42-G45 PolarHBondContact O-N 3.12Å; L42-G45 VanDerWaalsContact O-N 3.13Å; P43-G45 VanDerWaalsContact C-N 3.3Å; P43-G45 PolarHBondContact O-N 3.35Å; G45-L48 PolarHBondContact O-N 3.48Å; G45-I49 PolarHBondContact O-N 3.12Å
46	I	86.9	Confident	80.7	Confident	36 Å²	36	49 Å²	49	19%	0.185	25%	0.252	C	S	.	.	H	α-helix	trans	-61.8	-48.2	175.1	-65.8	164.4	0	0	0	110.3	L42 P43 L48 I49 V50 A265 I268	L42-I46 HydrophobicContact CD1-CD1 4.22Å; L42-I46 HydrophobicContact CD1-CG1 4.35Å; L42-I46 HydrophobicContact CG-CD1 4.2Å; L42-I46 WeakPolarHBondContact O-CG1 3.39Å; L42-I46 PolarHBondContact O-N 3.41Å; P43-I46 PolarHBondContact O-N 2.72Å; I46-L48 VanDerWaalsContact C-N 3.26Å; I46-L48 PolarHBondContact O-N 3.2Å; I46-I49 PolarHBondContact O-N 2.92Å; I46-V50 HydrophobicContact CG2-CG2 4.19Å; I46-V50 WeakPolarHBondContact O-CB 3.28Å; I46-V50 VanDerWaalsContact O-CG2 3.31Å; I46-V50 WeakPolarHBondContact O-CG2 3.34Å; I46-V50 PolarHBondContact O-N 3.42Å; I46-A265 HydrophobicContact CG1-CB 4.17Å; I46-I268 HydrophobicContact CD1-CB 4.27Å; I46-I268 HydrophobicContact CD1-CD1 3.87Å; I46-I268 HydrophobicContact CD1-CG2 4.05Å; I46-I268 HydrophobicContact CG1-CB 4.49Å; I46-I268 HydrophobicContact CG1-CG2 4.48Å; I46-I268 HydrophobicContact CG2-CG2 4.41Å
47	C	82.3	Confident	82.3	Confident	56 Å²	56	44.3 Å²	44.3	38%	0.378	23%	0.229	S	C	.	.	H	α-helix	trans	-59.4	-38.9	178	-169.7	0	0	0	0	111.7	P43 N44 G51	P43-C47 WeakPolarHBondContact O-CB 3.46Å; P43-C47 PolarHBondContact O-N 2.87Å; N44-C47 PolarHBondContact O-N 3.44Å; C47-G51 VanDerWaalsContact O-CA 3.29Å; C47-G51 WeakPolarHBondContact O-CA 3.27Å; C47-G51 PolarHBondContact O-N 2.96Å
48	L	80.6	Confident	83.4	Confident	46 Å²	46	36.9 Å²	36.9	24%	0.241	20%	0.197	C	C	.	.	H	α-helix	trans	-68	-44.2	178.6	-172	160.5	0	0	0	111.9	N44 G45 I46 N52 T247 L248	N44-L48 VanDerWaalsContact O-CB 3.26Å; N44-L48 WeakPolarHBondContact O-CB 3.45Å; N44-L48 PolarHBondContact O-N 2.82Å; G45-L48 PolarHBondContact O-N 3.48Å; I46-L48 VanDerWaalsContact C-N 3.26Å; I46-L48 PolarHBondContact O-N 3.2Å; L48-N52 VanDerWaalsContact O-CB 3.32Å; L48-N52 WeakPolarHBondContact O-CB 3.33Å; L48-N52 PolarHBondContact O-N 3.45Å; L48-T247 HydrophobicContact CD2-CG2 3.89Å; L48-L248 HydrophobicContact CB-CD2 4.25Å; L48-L248 HydrophobicContact CD1-CD2 3.97Å; L48-L248 HydrophobicContact CD2-CD2 3.7Å; L48-L248 HydrophobicContact CD2-CG 4.12Å; L48-L248 HydrophobicContact CG-CD2 4.19Å
49	I	85.1	Confident	84	Confident	0 Å²	0	29.6 Å²	29.6	0%	0	17%	0.17	C	C	.	.	H	α-helix	trans	-64.2	-54.4	175.4	-67.5	174.4	0	0	0	110.6	G45 I46 G51 N52 M53 L248 A265 I266 S269	G45-I49 PolarHBondContact O-N 3.12Å; I46-I49 PolarHBondContact O-N 2.92Å; I49-G51 VanDerWaalsContact C-N 3.26Å; I49-G51 PolarHBondContact O-N 3.23Å; I49-N52 PolarHBondContact O-N 2.92Å; I49-M53 HydrophobicContact CG2-CG 4.15Å; I49-M53 HydrophobicContact CG2-SD 3.54Å; I49-M53 VanDerWaalsContact CG2-SD 3.54Å; I49-M53 WeakPolarHBondContact O-CB 3.23Å; I49-M53 WeakPolarHBondContact O-CG 3.49Å; I49-M53 PolarHBondContact O-N 3.32Å; I49-L248 HydrophobicContact CD1-CD1 3.4Å; I49-L248 HydrophobicContact CD1-CG 3.95Å; I49-L248 HydrophobicContact CG1-CD1 3.63Å; I49-L248 HydrophobicContact CG1-CG 3.69Å; I49-A265 HydrophobicContact CD1-CB 4.06Å; I49-I266 HydrophobicContact CD1-CB 4.47Å; I49-I266 HydrophobicContact CD1-CG1 3.68Å; I49-S269 VanDerWaalsContact CG2-CB 3.43Å
50	V	85.8	Confident	84.5	Confident	14 Å²	14	24.3 Å²	24.3	9%	0.085	15%	0.146	C	C	.	.	H	α-helix	trans	-60.4	-42.5	-178	174.7	0	0	0	0	110	I46 I54 L195 V273	I46-V50 HydrophobicContact CG2-CG2 4.19Å; I46-V50 WeakPolarHBondContact O-CB 3.28Å; I46-V50 VanDerWaalsContact O-CG2 3.31Å; I46-V50 WeakPolarHBondContact O-CG2 3.34Å; I46-V50 PolarHBondContact O-N 3.42Å; V50-I54 HydrophobicContact CG1-CD1 3.56Å; V50-I54 HydrophobicContact CG1-CG1 4.21Å; V50-I54 WeakPolarHBondContact O-CB 3.43Å; V50-I54 VanDerWaalsContact O-CG1 3.25Å; V50-I54 WeakPolarHBondContact O-CG1 3.35Å; V50-I54 PolarHBondContact O-N 3.4Å; V50-L195 HydrophobicContact CG1-CD2 4.24Å; V50-V273 HydrophobicContact CG1-CG2 4.43Å; V50-V273 HydrophobicContact CG2-CG2 4.23Å
51	G	79.8	Confident	85.2	Confident	5 Å²	5	23.2 Å²	23.2	5%	0.052	14%	0.14	C	C	.	.	H	α-helix	trans	-62.8	-43.1	176.2	0	0	0	0	0	112.6	C47 I49 K194	C47-G51 VanDerWaalsContact O-CA 3.29Å; C47-G51 WeakPolarHBondContact O-CA 3.27Å; C47-G51 PolarHBondContact O-N 2.96Å; I49-G51 VanDerWaalsContact C-N 3.26Å; I49-G51 PolarHBondContact O-N 3.23Å; G51-K194 PolarHBondContact O-NZ 3.43Å
52	N	79.3	Confident	85.5	Confident	43 Å²	43	21.8 Å²	21.8	23%	0.23	13%	0.13	C	C	.	.	H	α-helix	trans	-76.2	-39.8	-179.1	-74.9	-6.1	0	0	0	112.7	L48 I49 T247	L48-N52 VanDerWaalsContact O-CB 3.32Å; L48-N52 WeakPolarHBondContact O-CB 3.33Å; L48-N52 PolarHBondContact O-N 3.45Å; I49-N52 PolarHBondContact O-N 2.92Å; N52-T247 WeakPolarHBondContact ND2-CB 3.3Å; N52-T247 WeakPolarHBondContact ND2-CG2 3.43Å; N52-T247 PolarHBondContact ND2-OG1 3.07Å
53	M	85.6	Confident	85.9	Confident	4 Å²	4	20.9 Å²	20.9	2%	0.02	13%	0.125	C	C	.	.	H	α-helix	trans	-66.4	-50.1	177.9	-69.8	178.9	78.7	0	0	111.5	I49 G55 Y242 W245 M270 V273 Y277	I49-M53 HydrophobicContact CG2-CG 4.15Å; I49-M53 HydrophobicContact CG2-SD 3.54Å; I49-M53 VanDerWaalsContact CG2-SD 3.54Å; I49-M53 WeakPolarHBondContact O-CB 3.23Å; I49-M53 WeakPolarHBondContact O-CG 3.49Å; I49-M53 PolarHBondContact O-N 3.32Å; M53-G55 PolarHBondContact O-N 3.29Å; M53-Y242 HydrophobicContact CE-CD1 3.79Å; M53-Y242 VanDerWaalsContact CE-O 3.28Å; M53-Y242 WeakPolarHBondContact CE-O 3.4Å; M53-W245 HydrophobicContact CE-CB 4.24Å; M53-W245 HydrophobicContact CG-CB 4.29Å; M53-W245 HydrophobicContact SD-CB 3.77Å; M53-M270 HydrophobicContact CE-CE 3.6Å; M53-M270 HydrophobicContact CE-SD 3.59Å; M53-M270 VanDerWaalsContact CE-SD 3.59Å; M53-M270 HydrophobicContact SD-CE 4.45Å; M53-M270 HydrophobicContact SD-SD 3.63Å; M53-M270 VanDerWaalsContact SD-SD 3.63Å; M53-V273 HydrophobicContact CB-CG1 4.28Å; M53-V273 HydrophobicContact CB-CG2 4.29Å; M53-V273 HydrophobicContact CE-CB 4.26Å; M53-V273 HydrophobicContact CE-CG1 3.87Å; M53-V273 HydrophobicContact CE-CG2 4.47Å; M53-V273 HydrophobicContact SD-CB 4.44Å; M53-V273 HydrophobicContact SD-CG1 4.42Å; M53-V273 HydrophobicContact SD-CG2 4.03Å; M53-Y277 VanDerWaalsContact C-OH 3.29Å; M53-Y277 PolarHBondContact O-OH 3.2Å
54	I	85.1	Confident	86.3	Confident	0 Å²	0	16.8 Å²	16.8	0%	0	10%	0.098	C	C	.	.	S	Bend	trans	-73.9	81.2	178.2	-57.9	-176	0	0	0	108.5	V50 K194 L195 L198 V273 I276 Y277	V50-I54 HydrophobicContact CG1-CD1 3.56Å; V50-I54 HydrophobicContact CG1-CG1 4.21Å; V50-I54 WeakPolarHBondContact O-CB 3.43Å; V50-I54 VanDerWaalsContact O-CG1 3.25Å; V50-I54 WeakPolarHBondContact O-CG1 3.35Å; V50-I54 PolarHBondContact O-N 3.4Å; I54-K194 HydrophobicContact CG2-CD 4.47Å; I54-K194 VanDerWaalsContact O-CD 3.23Å; I54-K194 WeakPolarHBondContact O-CD 3.21Å; I54-K194 WeakPolarHBondContact O-CE 3.36Å; I54-K194 PolarHBondContact O-NZ 2.98Å; I54-L195 HydrophobicContact CD1-CD2 3.91Å; I54-L198 HydrophobicContact CD1-CD1 4.48Å; I54-L198 HydrophobicContact CG2-CD1 3.2Å; I54-V273 HydrophobicContact CD1-CG2 4.23Å; I54-V273 HydrophobicContact CG1-CG1 4.25Å; I54-V273 HydrophobicContact CG1-CG2 4.05Å; I54-I276 HydrophobicContact CD1-CD1 3.88Å; I54-I276 HydrophobicContact CD1-CG2 4.35Å; I54-Y277 WeakPolarHBondContact CA-OH 3.29Å; I54-Y277 HydrophobicContact CG1-CE1 4.06Å
55	G	79.2	Confident	87	Confident	8 Å²	8	12.5 Å²	12.5	8%	0.082	8%	0.075	C	C	.	.	S	Bend	trans	-119.1	-140.9	-178	0	0	0	0	0	112.7	M53 G57 F59	M53-G55 PolarHBondContact O-N 3.29Å; G55-G57 VanDerWaalsContact C-N 3.27Å; G55-F59 WeakPolarHBondContact O-CD2 3.32Å; G55-F59 WeakPolarHBondContact O-CE2 3.4Å
56	S	79.4	Confident	87.6	Confident	5 Å²	5	12.4 Å²	12.4	4%	0.035	7%	0.074	C	C	.	.	S	Bend	trans	-69.9	-23.6	173.8	57	0	0	0	0	112.9	I58 F59 V60 I138	S56-I58 PolarHBondContact O-N 3.05Å; S56-F59 WeakPolarHBondContact O-CB 3.23Å; S56-F59 PolarHBondContact O-N 2.67Å; S56-V60 PolarHBondContact O-N 3.2Å; S56-I138 VanDerWaalsContact OG-CG1 3.29Å; S56-I138 WeakPolarHBondContact OG-CG1 3.25Å
57	G	87.9	Confident	87.9	Confident	4 Å²	4	15.1 Å²	15.1	4%	0.041	9%	0.087	C	C	.	.	H	α-helix	trans	-57	-45.7	-172.9	0	0	0	0	0	113.9	G55 F59 V60 S61 S241	G55-G57 VanDerWaalsContact C-N 3.27Å; G57-F59 PolarHBondContact O-N 2.83Å; G57-V60 PolarHBondContact O-N 2.6Å; G57-V60 VanDerWaalsContact O-N 3.12Å; G57-S61 WeakPolarHBondContact O-CB 3.33Å; G57-S61 PolarHBondContact O-N 3.35Å; G57-S61 PolarHBondContact O-OG 3.24Å; G57-S241 PolarHBondContact O-OG 3.3Å
58	I	91.6	Very high	88.5	Confident	0 Å²	0	14.5 Å²	14.5	0%	0	8%	0.078	C	C	.	.	H	α-helix	trans	-63.5	-17.3	179.2	-167.9	53.9	0	0	0	113.6	S56 P62 W79 L198 Y277 T280	S56-I58 PolarHBondContact O-N 3.05Å; I58-P62 WeakPolarHBondContact O-CD 3.14Å; I58-P62 WeakPolarHBondContact O-CG 3.48Å; I58-W79 HydrophobicContact CD1-CH2 3.57Å; I58-W79 HydrophobicContact CD1-CZ2 4.13Å; I58-W79 HydrophobicContact CD1-CZ3 4.01Å; I58-L198 HydrophobicContact CG1-CD2 4.46Å; I58-L198 HydrophobicContact CG2-CD2 4.17Å; I58-Y277 HydrophobicContact CB-CD1 4.11Å; I58-Y277 HydrophobicContact CB-CE1 3.74Å; I58-Y277 HydrophobicContact CD1-CD1 3.58Å; I58-Y277 HydrophobicContact CD1-CE1 4.11Å; I58-Y277 HydrophobicContact CD1-CG 3.83Å; I58-Y277 HydrophobicContact CG1-CD1 3.73Å; I58-Y277 HydrophobicContact CG1-CE1 3.89Å; I58-Y277 HydrophobicContact CG1-CG 4.47Å; I58-Y277 HydrophobicContact CG2-CE1 4.36Å; I58-T280 HydrophobicContact CD1-CG2 4.38Å; I58-T280 HydrophobicContact CG1-CG2 4.05Å
59	F	89.8	Confident	89.2	Confident	1 Å²	1	12.3 Å²	12.3	0%	0.004	7%	0.067	C	C	.	.	H	α-helix	trans	-93	-20.3	-179.7	-62.6	-55.2	0	0	0	112.9	G55 S56 G57 T141 Y145 L198 I201 A300 V319	G55-F59 WeakPolarHBondContact O-CD2 3.32Å; G55-F59 WeakPolarHBondContact O-CE2 3.4Å; S56-F59 WeakPolarHBondContact O-CB 3.23Å; S56-F59 PolarHBondContact O-N 2.67Å; G57-F59 PolarHBondContact O-N 2.83Å; F59-T141 HydrophobicContact CB-CG2 4.49Å; F59-Y145 HydrophobicContact CB-CE1 4.49Å; F59-Y145 HydrophobicContact CB-CE2 3.99Å; F59-Y145 WeakPolarHBondContact CB-OH 3.12Å; F59-Y145 PolarHBondContact O-OH 3.4Å; F59-L198 HydrophobicContact CE1-CD2 3.96Å; F59-L198 HydrophobicContact CZ-CD2 3.94Å; F59-L198 HydrophobicContact CZ-CG 4.37Å; F59-I201 HydrophobicContact CE1-CD1 4.48Å; F59-A300 HydrophobicContact CD1-CB 3.84Å; F59-A300 HydrophobicContact CE1-CB 4.18Å; F59-V319 HydrophobicContact CB-CG1 4.12Å; F59-V319 HydrophobicContact CD1-CG1 4.28Å; F59-V319 HydrophobicContact CD1-CG2 3.78Å; F59-V319 HydrophobicContact CD2-CB 4.39Å; F59-V319 HydrophobicContact CD2-CG1 3.54Å; F59-V319 HydrophobicContact CD2-CG2 4.14Å; F59-V319 HydrophobicContact CE1-CG2 3.58Å; F59-V319 HydrophobicContact CE2-CB 4.39Å; F59-V319 HydrophobicContact CE2-CG1 3.99Å; F59-V319 HydrophobicContact CE2-CG2 3.96Å; F59-V319 HydrophobicContact CG-CG1 3.7Å; F59-V319 HydrophobicContact CG-CG2 4.06Å; F59-V319 HydrophobicContact CZ-CG2 3.67Å
60	V	90.8	Very high	89.6	Confident	16 Å²	16	13.3 Å²	13.3	10%	0.097	8%	0.077	C	C	.	.	H	α-helix	trans	-104.4	-46.8	178.9	179.4	0	0	0	0	111.8	S56 G57 K63 T141 V381 F382 I385	S56-V60 PolarHBondContact O-N 3.2Å; G57-V60 PolarHBondContact O-N 2.6Å; G57-V60 VanDerWaalsContact O-N 3.12Å; V60-K63 PolarHBondContact O-N 2.8Å; V60-T141 HydrophobicContact CG2-CG2 3.55Å; V60-T141 WeakPolarHBondContact CG2-OG1 3.41Å; V60-V381 HydrophobicContact CG1-CG1 4.28Å; V60-F382 HydrophobicContact CG1-CE1 4.27Å; V60-F382 HydrophobicContact CG1-CZ 4.37Å; V60-I385 HydrophobicContact CG1-CD1 3.92Å
61	S	94.3	Very high	90	Very high	0 Å²	0	12.9 Å²	12.9	0%	0	8%	0.075	C	C	.	.	H	α-helix	trans	-63	-30.7	-169.6	-55.8	0	0	0	0	115.9	G57 K63 G64 V65 S237 S241	G57-S61 WeakPolarHBondContact O-CB 3.33Å; G57-S61 PolarHBondContact O-N 3.35Å; G57-S61 PolarHBondContact O-OG 3.24Å; S61-K63 PolarHBondContact O-N 3.27Å; S61-K63 VanDerWaalsContact O-N 3.17Å; S61-G64 PolarHBondContact O-N 3.22Å; S61-G64 VanDerWaalsContact O-N 3.08Å; S61-V65 VanDerWaalsContact O-CG2 3.29Å; S61-V65 WeakPolarHBondContact O-CG2 3.39Å; S61-V65 PolarHBondContact O-N 3.04Å; S61-S237 WeakPolarHBondContact CB-O 3.23Å; S61-S237 PolarHBondContact OG-O 3.2Å; S61-S241 WeakPolarHBondContact CB-OG 3.29Å; S61-S241 PolarHBondContact OG-OG 2.87Å
62	P	95.4	Very high	90.7	Very high	0 Å²	0	13.7 Å²	13.7	0%	0	8%	0.076	C	C	.	.	H	α-helix	trans	-53.3	-37.4	176.7	-29.2	36.4	0	0	0	113.6	I58 L66 W79 N281 Y284	I58-P62 WeakPolarHBondContact O-CD 3.14Å; I58-P62 WeakPolarHBondContact O-CG 3.48Å; P62-L66 VanDerWaalsContact O-CB 3.24Å; P62-L66 WeakPolarHBondContact O-CB 3.14Å; P62-L66 PolarHBondContact O-N 3.26Å; P62-W79 HydrophobicContact CG-CZ2 4.18Å; P62-N281 WeakPolarHBondContact CB-OD1 3.49Å; P62-Y284 HydrophobicContact CB-CD2 4.18Å; P62-Y284 HydrophobicContact CB-CE2 4.47Å; P62-Y284 HydrophobicContact CG-CD2 4.08Å; P62-Y284 HydrophobicContact CG-CE2 3.93Å
63	K	94.8	Very high	91.5	Very high	22 Å²	22	11.9 Å²	11.9	10%	0.096	7%	0.068	C	C	.	.	H	α-helix	trans	-64.4	-51.4	174.9	176.7	-178.4	-172.9	153	0	111.3	V60 S61 L66 M67 L293 L294 S296 D297 V299 F382	V60-K63 PolarHBondContact O-N 2.8Å; S61-K63 PolarHBondContact O-N 3.27Å; S61-K63 VanDerWaalsContact O-N 3.17Å; K63-L66 PolarHBondContact O-N 3.03Å; K63-M67 HydrophobicContact CG-CE 4.32Å; K63-M67 VanDerWaalsContact O-CB 3.23Å; K63-M67 WeakPolarHBondContact O-CB 3.34Å; K63-M67 PolarHBondContact O-N 3.45Å; K63-L293 HydrophobicContact CB-CD2 4.43Å; K63-L294 WeakPolarHBondContact CE-O 3.22Å; K63-L294 PolarHBondContact NZ-O 2.97Å; K63-S296 VanDerWaalsContact CD-O 3.26Å; K63-S296 WeakPolarHBondContact CD-O 3.4Å; K63-S296 WeakPolarHBondContact CE-O 3.35Å; K63-S296 PolarHBondContact NZ-O 3.38Å; K63-D297 IonicContact NZ-OD1 2.67Å; K63-D297 PolarHBondContact NZ-OD1 3.08Å; K63-V299 HydrophobicContact CB-CG2 4.24Å; K63-F382 HydrophobicContact CB-CZ 4.13Å; K63-F382 HydrophobicContact CD-CE2 4Å; K63-F382 HydrophobicContact CD-CZ 3.94Å; K63-F382 HydrophobicContact CG-CE2 4.37Å; K63-F382 HydrophobicContact CG-CZ 3.98Å
64	G	93.6	Very high	92	Very high	0 Å²	0	13.1 Å²	13.1	0%	0	8%	0.075	C	C	.	.	H	α-helix	trans	-63.9	-43.4	-179	0	0	0	0	0	113.1	S61 M67 H68 F382	S61-G64 PolarHBondContact O-N 3.22Å; S61-G64 VanDerWaalsContact O-N 3.08Å; G64-M67 PolarHBondContact O-N 3.38Å; G64-H68 PolarHBondContact O-CD2 3.47Å; G64-H68 VanDerWaalsContact O-CD2 3.23Å; G64-H68 PolarHBondContact O-N 2.96Å; G64-F382 VanDerWaalsContact CA-CE1 3.43Å
65	V	96.4	Very high	92.5	Very high	0 Å²	0	13.1 Å²	13.1	0%	0	8%	0.075	C	C	.	.	H	α-helix	trans	-63.1	-45.1	176.4	-176.7	0	0	0	0	110.5	S61 S69 S75 I78 W79 A234 A238	S61-V65 VanDerWaalsContact O-CG2 3.29Å; S61-V65 WeakPolarHBondContact O-CG2 3.39Å; S61-V65 PolarHBondContact O-N 3.04Å; V65-S69 WeakPolarHBondContact O-CB 3.37Å; V65-S69 PolarHBondContact O-N 3.36Å; V65-S69 PolarHBondContact O-OG 2.91Å; V65-S75 VanDerWaalsContact CG1-OG 3.23Å; V65-S75 WeakPolarHBondContact CG1-OG 3.32Å; V65-I78 HydrophobicContact CG1-CB 4.18Å; V65-I78 HydrophobicContact CG1-CG2 3.92Å; V65-W79 HydrophobicContact CG2-CZ2 4.23Å; V65-A234 HydrophobicContact CG1-CB 4.48Å; V65-A238 HydrophobicContact CG2-CB 3.91Å
66	L	95.8	Very high	93.4	Very high	0 Å²	0	14.3 Å²	14.3	0%	0	8%	0.079	C	C	.	.	H	α-helix	trans	-68	-39.6	179.9	-169	62.9	0	0	0	112.4	P62 K63 H68 S69 G70 Y72 Y285 M290 L293 L294	P62-L66 VanDerWaalsContact O-CB 3.24Å; P62-L66 WeakPolarHBondContact O-CB 3.14Å; P62-L66 PolarHBondContact O-N 3.26Å; K63-L66 PolarHBondContact O-N 3.03Å; L66-H68 VanDerWaalsContact C-N 3.33Å; L66-H68 PolarHBondContact O-N 2.92Å; L66-S69 WeakPolarHBondContact CA-OG 3.48Å; L66-S69 PolarHBondContact O-N 3.3Å; L66-S69 PolarHBondContact O-OG 3.2Å; L66-G70 PolarHBondContact O-N 3.44Å; L66-Y72 HydrophobicContact CD1-CD1 3.67Å; L66-Y72 HydrophobicContact CD1-CE1 4.14Å; L66-Y72 HydrophobicContact CD2-CD1 4.16Å; L66-Y72 HydrophobicContact CD2-CE1 3.85Å; L66-Y285 HydrophobicContact CD1-CE1 4.44Å; L66-Y285 HydrophobicContact CD2-CE1 4.12Å; L66-M290 HydrophobicContact CD1-CE 3.88Å; L66-M290 HydrophobicContact CD2-CE 4.4Å; L66-M290 HydrophobicContact CD2-CG 3.97Å; L66-M290 HydrophobicContact CG-CE 3.83Å; L66-M290 HydrophobicContact CG-CG 4.4Å; L66-L293 HydrophobicContact CB-CD2 4.35Å; L66-L293 HydrophobicContact CD2-CB 4.28Å; L66-L293 HydrophobicContact CD2-CD1 4.02Å; L66-L293 HydrophobicContact CD2-CD2 3.75Å; L66-L293 HydrophobicContact CD2-CG 4.22Å; L66-L294 HydrophobicContact CB-CD2 4.19Å; L66-L294 HydrophobicContact CD2-CD2 4.39Å; L66-L294 HydrophobicContact CD2-CG 4.49Å; L66-L294 HydrophobicContact CG-CD2 4.3Å
67	M	94.5	Very high	94.2	Very high	93 Å²	93	17 Å²	17	46%	0.458	10%	0.095	S	C	.	.	H	α-helix	trans	-58.3	-44.9	178.7	-175.6	-177.9	-64.5	0	0	111.8	K63 G64 L294	K63-M67 HydrophobicContact CG-CE 4.32Å; K63-M67 VanDerWaalsContact O-CB 3.23Å; K63-M67 WeakPolarHBondContact O-CB 3.34Å; K63-M67 PolarHBondContact O-N 3.45Å; G64-M67 PolarHBondContact O-N 3.38Å; M67-L294 HydrophobicContact CB-CD2 3.83Å
68	H	93.8	Very high	94.6	Very high	43 Å²	43	17 Å²	17	20%	0.199	9%	0.094	C	C	.	.	H	α-helix	trans	-87.4	-26.3	-177.6	-70.8	-60.2	0	0	0	113.8	G64 L66 S225 S230 A234	G64-H68 PolarHBondContact O-CD2 3.47Å; G64-H68 VanDerWaalsContact O-CD2 3.23Å; G64-H68 PolarHBondContact O-N 2.96Å; L66-H68 VanDerWaalsContact C-N 3.33Å; L66-H68 PolarHBondContact O-N 2.92Å; H68-S225 VanDerWaalsContact O-CB 3.27Å; H68-S225 WeakPolarHBondContact O-CB 3.15Å; H68-S230 WeakPolarHBondContact CB-O 3.23Å; H68-A234 HydrophobicContact CB-CB 3.72Å
69	S	94.9	Very high	94.9	Very high	0 Å²	0	17 Å²	17	0%	0	9%	0.094	C	C	.	.	H	α-helix	trans	-80	-28.1	176.4	62.2	0	0	0	0	113.3	V65 L66 S71 L74 S75 S225	V65-S69 WeakPolarHBondContact O-CB 3.37Å; V65-S69 PolarHBondContact O-N 3.36Å; V65-S69 PolarHBondContact O-OG 2.91Å; L66-S69 WeakPolarHBondContact CA-OG 3.48Å; L66-S69 PolarHBondContact O-N 3.3Å; L66-S69 PolarHBondContact O-OG 3.2Å; S69-S71 PolarHBondContact O-N 2.92Å; S69-S71 VanDerWaalsContact O-N 3.12Å; S69-S71 PolarHBondContact OG-O 3.22Å; S69-L74 WeakPolarHBondContact O-CD2 3.39Å; S69-S75 WeakPolarHBondContact OG-CB 3.41Å; S69-S225 PolarHBondContact O-N 2.68Å
70	G	93.5	Very high	95.3	Very high	22 Å²	22	18.3 Å²	18.3	23%	0.227	11%	0.106	C	C	.	.			trans	70.9	-0.8	178.5	0	0	0	0	0	115.1	L66 G223 M290	L66-G70 PolarHBondContact O-N 3.44Å; G70-G223 CarbonylContact C-O 3.47Å; G70-G223 CarbonylContact O-C 3.44Å; G70-M290 VanDerWaalsContact C-CE 3.44Å; G70-M290 WeakPolarHBondContact O-CE 3.45Å
71	S	94.6	Very high	95.5	Very high	4 Å²	4	21.9 Å²	21.9	3%	0.028	12%	0.123	C	C	.	.	S	Bend	trans	-154.8	153.6	177.3	76.1	0	0	0	0	112.5	S69 L74 S75 P220 E222 S224	S69-S71 PolarHBondContact O-N 2.92Å; S69-S71 VanDerWaalsContact O-N 3.12Å; S69-S71 PolarHBondContact OG-O 3.22Å; S71-L74 VanDerWaalsContact OG-CB 3.23Å; S71-L74 WeakPolarHBondContact OG-CB 3.37Å; S71-L74 PolarHBondContact OG-N 3.11Å; S71-L74 VanDerWaalsContact OG-N 3.17Å; S71-S75 VanDerWaalsContact O-CB 3.31Å; S71-S75 WeakPolarHBondContact O-CB 3.48Å; S71-S75 PolarHBondContact O-N 2.76Å; S71-P220 WeakPolarHBondContact CB-O 3.2Å; S71-P220 PolarHBondContact OG-O 3.37Å; S71-E222 WeakPolarHBondContact CB-O 3.39Å; S71-S224 PolarHBondContact OG-OG 2.93Å
72	Y	94.9	Very high	95.5	Very high	22 Å²	22	21.9 Å²	21.9	9%	0.086	12%	0.123	C	C	.	.	H	α-helix	trans	-65.7	-40.3	179.1	-56.8	-55	0	0	0	112.7	L66 S75 L76 N216 P220 Y285 M290	L66-Y72 HydrophobicContact CD1-CD1 3.67Å; L66-Y72 HydrophobicContact CD1-CE1 4.14Å; L66-Y72 HydrophobicContact CD2-CD1 4.16Å; L66-Y72 HydrophobicContact CD2-CE1 3.85Å; Y72-S75 WeakPolarHBondContact O-CB 3.31Å; Y72-S75 PolarHBondContact O-N 2.89Å; Y72-L76 WeakPolarHBondContact O-CG 3.42Å; Y72-L76 PolarHBondContact O-N 2.9Å; Y72-N216 HydrophobicContact CD2-CB 4.3Å; Y72-N216 VanDerWaalsContact CD2-O 3.23Å; Y72-N216 WeakPolarHBondContact CD2-O 3.45Å; Y72-N216 HydrophobicContact CE2-CB 3.73Å; Y72-P220 PolarHBondContact N-O 3.27Å; Y72-Y285 AromaticContact CD1-CD1 3.56Å; Y72-Y285 HydrophobicContact CD1-CD1 3.56Å; Y72-Y285 AromaticContact CD1-CD2 3.84Å; Y72-Y285 HydrophobicContact CD1-CD2 3.84Å; Y72-Y285 AromaticContact CD1-CE1 4Å; Y72-Y285 HydrophobicContact CD1-CE1 4Å; Y72-Y285 HydrophobicContact CD1-CE2 4.22Å; Y72-Y285 AromaticContact CD1-CG 3.5Å; Y72-Y285 HydrophobicContact CD1-CG 3.5Å; Y72-Y285 AromaticContact CE1-CD1 3.8Å; Y72-Y285 HydrophobicContact CE1-CD1 3.8Å; Y72-Y285 HydrophobicContact CE1-CE1 4.39Å; Y72-Y285 HydrophobicContact CE1-CG 4.05Å; Y72-Y285 HydrophobicContact CG-CD2 4.18Å; Y72-Y285 HydrophobicContact CG-CG 4.11Å; Y72-M290 HydrophobicContact CE1-CB 4.29Å; Y72-M290 WeakPolarHBondContact OH-CA 3.49Å; Y72-M290 WeakPolarHBondContact OH-CB 3.28Å; Y72-M290 PolarHBondContact OH-N 3.44Å
73	G	95	Very high	95.5	Very high	6 Å²	6	21.9 Å²	21.9	6%	0.062	12%	0.124	C	C	.	.	H	α-helix	trans	-65	-48.5	-179.1	0	0	0	0	0	111.7	S75 L76 V77 P220 F221	G73-S75 VanDerWaalsContact C-N 3.34Å; G73-L76 PolarHBondContact O-N 3.46Å; G73-V77 WeakPolarHBondContact O-CG2 3.48Å; G73-V77 PolarHBondContact O-N 3.12Å; G73-V77 VanDerWaalsContact O-N 3.11Å; G73-P220 WeakPolarHBondContact CA-O 3.47Å; G73-P220 PolarHBondContact N-O 2.84Å; G73-F221 VanDerWaalsContact C-CE1 3.44Å
74	L	96.2	Very high	95.5	Very high	30 Å²	30	25.2 Å²	25.2	16%	0.157	14%	0.142	C	C	.	.	H	α-helix	trans	-65.9	-38.5	176	-175.1	60.1	0	0	0	111.4	S69 S71 L76 V77 I78 S225	S69-L74 WeakPolarHBondContact O-CD2 3.39Å; S71-L74 VanDerWaalsContact OG-CB 3.23Å; S71-L74 WeakPolarHBondContact OG-CB 3.37Å; S71-L74 PolarHBondContact OG-N 3.11Å; S71-L74 VanDerWaalsContact OG-N 3.17Å; L74-L76 PolarHBondContact O-N 3.46Å; L74-V77 PolarHBondContact O-N 3Å; L74-I78 HydrophobicContact CD1-CD1 4.4Å; L74-I78 HydrophobicContact CD1-CG1 4.44Å; L74-I78 HydrophobicContact CG-CD1 3.96Å; L74-I78 HydrophobicContact CG-CG1 4.44Å; L74-I78 VanDerWaalsContact O-CG1 3.31Å; L74-I78 WeakPolarHBondContact O-CG1 3.43Å; L74-I78 PolarHBondContact O-N 3.4Å; L74-S225 WeakPolarHBondContact CD2-O 3.16Å
75	S	96.9	Very high	95.5	Very high	0 Å²	0	26.2 Å²	26.2	0%	0	15%	0.146	C	C	.	.	H	α-helix	trans	-55.8	-49.2	174.1	179.9	0	0	0	0	112.2	V65 S69 S71 Y72 G73 V77 I78 W79 Y285	V65-S75 VanDerWaalsContact CG1-OG 3.23Å; V65-S75 WeakPolarHBondContact CG1-OG 3.32Å; S69-S75 WeakPolarHBondContact OG-CB 3.41Å; S71-S75 VanDerWaalsContact O-CB 3.31Å; S71-S75 WeakPolarHBondContact O-CB 3.48Å; S71-S75 PolarHBondContact O-N 2.76Å; Y72-S75 WeakPolarHBondContact O-CB 3.31Å; Y72-S75 PolarHBondContact O-N 2.89Å; G73-S75 VanDerWaalsContact C-N 3.34Å; S75-V77 VanDerWaalsContact C-N 3.32Å; S75-V77 PolarHBondContact O-N 2.67Å; S75-I78 WeakPolarHBondContact O-CB 3.41Å; S75-I78 PolarHBondContact O-N 2.64Å; S75-I78 VanDerWaalsContact O-N 3.11Å; S75-W79 VanDerWaalsContact O-CD1 3.24Å; S75-W79 PolarHBondContact O-N 3.03Å; S75-Y285 WeakPolarHBondContact CB-OH 3.4Å; S75-Y285 PolarHBondContact OG-OH 2.92Å
76	L	96.9	Very high	95.3	Very high	33 Å²	33	26.2 Å²	26.2	17%	0.173	15%	0.146	C	C	.	.	H	α-helix	trans	-62.8	-37.7	178.1	-69.5	175.5	0	0	0	112.5	Y72 G73 L74 I78 W79 A80 F217 L278 N281 V282 Y285	Y72-L76 WeakPolarHBondContact O-CG 3.42Å; Y72-L76 PolarHBondContact O-N 2.9Å; G73-L76 PolarHBondContact O-N 3.46Å; L74-L76 PolarHBondContact O-N 3.46Å; L76-I78 VanDerWaalsContact C-N 3.33Å; L76-W79 PolarHBondContact O-N 3.01Å; L76-A80 PolarHBondContact O-N 3.23Å; L76-F217 HydrophobicContact CD1-CE1 3.97Å; L76-L278 HydrophobicContact CD2-CD2 4.32Å; L76-L278 WeakPolarHBondContact O-CD2 3.42Å; L76-N281 HydrophobicContact CD2-CB 3.83Å; L76-V282 HydrophobicContact CD1-CG2 3.95Å; L76-V282 HydrophobicContact CD2-CG2 3.91Å; L76-Y285 HydrophobicContact CD2-CD2 4.29Å; L76-Y285 HydrophobicContact CD2-CE2 3.96Å; L76-Y285 HydrophobicContact CG-CD2 4.27Å; L76-Y285 HydrophobicContact CG-CE2 4.01Å
77	V	97	Very high	95.2	Very high	62 Å²	62	28.1 Å²	28.1	38%	0.376	16%	0.157	S	C	.	.	H	α-helix	trans	-61.9	-42.7	173.3	171.2	0	0	0	0	110.6	G73 L74 S75 A80 L81 F221	G73-V77 WeakPolarHBondContact O-CG2 3.48Å; G73-V77 PolarHBondContact O-N 3.12Å; G73-V77 VanDerWaalsContact O-N 3.11Å; L74-V77 PolarHBondContact O-N 3Å; S75-V77 VanDerWaalsContact C-N 3.32Å; S75-V77 PolarHBondContact O-N 2.67Å; V77-A80 PolarHBondContact O-N 3.31Å; V77-L81 HydrophobicContact CG1-CD1 3.87Å; V77-L81 HydrophobicContact CG1-CG 4.19Å; V77-L81 WeakPolarHBondContact O-CB 3.46Å; V77-L81 VanDerWaalsContact O-CG 3.29Å; V77-L81 WeakPolarHBondContact O-CG 3.33Å; V77-L81 PolarHBondContact O-N 2.92Å; V77-F221 HydrophobicContact CG2-CE1 4.32Å
78	I	96.9	Very high	95.1	Very high	2 Å²	2	25.8 Å²	25.8	1%	0.01	15%	0.145	C	C	.	.	H	α-helix	trans	-64.7	-40.9	178.5	-70.4	170.3	0	0	0	111.4	V65 L74 S75 L76 L81 G82 A234 L235 A238	V65-I78 HydrophobicContact CG1-CB 4.18Å; V65-I78 HydrophobicContact CG1-CG2 3.92Å; L74-I78 HydrophobicContact CD1-CD1 4.4Å; L74-I78 HydrophobicContact CD1-CG1 4.44Å; L74-I78 HydrophobicContact CG-CD1 3.96Å; L74-I78 HydrophobicContact CG-CG1 4.44Å; L74-I78 VanDerWaalsContact O-CG1 3.31Å; L74-I78 WeakPolarHBondContact O-CG1 3.43Å; L74-I78 PolarHBondContact O-N 3.4Å; S75-I78 WeakPolarHBondContact O-CB 3.41Å; S75-I78 PolarHBondContact O-N 2.64Å; S75-I78 VanDerWaalsContact O-N 3.11Å; L76-I78 VanDerWaalsContact C-N 3.33Å; I78-L81 PolarHBondContact O-N 3.41Å; I78-G82 PolarHBondContact O-N 3.04Å; I78-A234 HydrophobicContact CD1-CB 3.6Å; I78-A234 HydrophobicContact CG2-CB 4.19Å; I78-L235 HydrophobicContact CG2-CD2 3.9Å; I78-L235 HydrophobicContact CG2-CG 4.05Å; I78-A238 HydrophobicContact CG2-CB 4.09Å
79	W	97.4	Very high	95.1	Very high	0 Å²	0	23.7 Å²	23.7	0%	0	14%	0.135	C	C	.	.	H	α-helix	trans	-59.7	-45.4	172	-82.5	101.5	0	0	0	112	I58 P62 V65 S75 L76 G82 G83 A238 S241 Y242 Y277 L278 N281	I58-W79 HydrophobicContact CD1-CH2 3.57Å; I58-W79 HydrophobicContact CD1-CZ2 4.13Å; I58-W79 HydrophobicContact CD1-CZ3 4.01Å; P62-W79 HydrophobicContact CG-CZ2 4.18Å; V65-W79 HydrophobicContact CG2-CZ2 4.23Å; S75-W79 VanDerWaalsContact O-CD1 3.24Å; S75-W79 PolarHBondContact O-N 3.03Å; L76-W79 PolarHBondContact O-N 3.01Å; W79-G82 PolarHBondContact O-N 2.86Å; W79-G83 PolarHBondContact O-N 2.79Å; W79-A238 HydrophobicContact CD2-CB 4.38Å; W79-A238 HydrophobicContact CE3-CB 4.43Å; W79-S241 WeakPolarHBondContact CH2-OG 3.49Å; W79-Y242 HydrophobicContact CE3-CD2 4.5Å; W79-Y242 AromaticContact CE3-CE2 3.65Å; W79-Y242 HydrophobicContact CE3-CE2 3.65Å; W79-Y242 HydrophobicContact CZ3-CE2 4.06Å; W79-Y242 WeakPolarHBondContact O-CE2 3.39Å; W79-Y242 PolarHBondContact O-OH 3.34Å; W79-Y277 AromaticContact CE3-CD2 3.95Å; W79-Y277 HydrophobicContact CE3-CD2 3.95Å; W79-Y277 HydrophobicContact CE3-CG 4.27Å; W79-Y277 HydrophobicContact CH2-CD2 4.47Å; W79-Y277 AromaticContact CZ3-CD2 3.43Å; W79-Y277 HydrophobicContact CZ3-CD2 3.43Å; W79-Y277 VanDerWaalsContact CZ3-CD2 3.43Å; W79-Y277 HydrophobicContact CZ3-CE2 4.09Å; W79-Y277 AromaticContact CZ3-CG 3.85Å; W79-Y277 HydrophobicContact CZ3-CG 3.85Å; W79-L278 HydrophobicContact CB-CD2 3.72Å; W79-N281 WeakPolarHBondContact CZ2-ND2 3.44Å; W79-N281 PolarHBondContact NE1-ND2 3.24Å; W79-N281 PolarHBondContact NE1-OD1 2.85Å
80	A	96.9	Very high	95	Very high	30 Å²	30	23.7 Å²	23.7	25%	0.248	14%	0.135	C	C	.	.	H	α-helix	trans	-63.7	-44	177.5	0	0	0	0	0	112.2	L76 V77 G82 G83 I84 L278	L76-A80 PolarHBondContact O-N 3.23Å; V77-A80 PolarHBondContact O-N 3.31Å; A80-G82 VanDerWaalsContact C-N 3.35Å; A80-G83 PolarHBondContact O-N 2.92Å; A80-I84 WeakPolarHBondContact O-CG1 3.14Å; A80-I84 PolarHBondContact O-N 3.42Å; A80-L278 HydrophobicContact CB-CD1 4.35Å; A80-L278 HydrophobicContact CB-CD2 4.3Å
81	L	95.4	Very high	94.9	Very high	90 Å²	90	24.5 Å²	24.5	47%	0.471	13%	0.134	S	C	.	.	H	α-helix	trans	-62.9	-40.6	175.8	-72.2	175.7	0	0	0	111.8	V77 I78 I84 F85 L235	V77-L81 HydrophobicContact CG1-CD1 3.87Å; V77-L81 HydrophobicContact CG1-CG 4.19Å; V77-L81 WeakPolarHBondContact O-CB 3.46Å; V77-L81 VanDerWaalsContact O-CG 3.29Å; V77-L81 WeakPolarHBondContact O-CG 3.33Å; V77-L81 PolarHBondContact O-N 2.92Å; I78-L81 PolarHBondContact O-N 3.41Å; L81-I84 PolarHBondContact O-N 3.08Å; L81-F85 WeakPolarHBondContact O-CB 3.23Å; L81-F85 PolarHBondContact O-N 3.37Å; L81-L235 HydrophobicContact CB-CD2 4.39Å
82	G	94.9	Very high	94.9	Very high	0 Å²	0	24.3 Å²	24.3	0%	0	13%	0.133	C	C	.	.	H	α-helix	trans	-58.2	-47.6	173.2	0	0	0	0	0	111.8	I78 W79 A80 F85 S86	I78-G82 PolarHBondContact O-N 3.04Å; W79-G82 PolarHBondContact O-N 2.86Å; A80-G82 VanDerWaalsContact C-N 3.35Å; G82-F85 PolarHBondContact O-N 3.31Å; G82-S86 PolarHBondContact O-N 3.19Å; G82-S86 PolarHBondContact O-OG 3.46Å
83	G	94.6	Very high	94.8	Very high	1 Å²	1	23.3 Å²	23.3	1%	0.01	13%	0.129	C	C	.	.	H	α-helix	trans	-60.6	-45.7	175.8	0	0	0	0	0	113.2	W79 A80 S86 V87	W79-G83 PolarHBondContact O-N 2.79Å; A80-G83 PolarHBondContact O-N 2.92Å; G83-S86 PolarHBondContact O-N 3.14Å; G83-V87 VanDerWaalsContact O-CG2 3.31Å; G83-V87 WeakPolarHBondContact O-CG2 3.47Å; G83-V87 PolarHBondContact O-N 2.91Å
84	I	94.3	Very high	94.6	Very high	92 Å²	92	23 Å²	23	47%	0.472	13%	0.126	S	C	.	.	H	α-helix	trans	-61.8	-45.7	176.8	-67.4	166.2	0	0	0	110.8	A80 L81 S86 V87 F88	A80-I84 WeakPolarHBondContact O-CG1 3.14Å; A80-I84 PolarHBondContact O-N 3.42Å; L81-I84 PolarHBondContact O-N 3.08Å; I84-S86 VanDerWaalsContact C-N 3.34Å; I84-S86 PolarHBondContact O-N 3.47Å; I84-V87 WeakPolarHBondContact O-CB 3.31Å; I84-V87 PolarHBondContact O-N 3.32Å; I84-F88 HydrophobicContact CG2-CD1 4.33Å; I84-F88 HydrophobicContact CG2-CE1 4.02Å; I84-F88 VanDerWaalsContact O-CD1 3.31Å; I84-F88 WeakPolarHBondContact O-CD1 3.43Å; I84-F88 PolarHBondContact O-N 2.85Å; I84-F88 VanDerWaalsContact O-N 3.11Å
85	F	93.8	Very high	94.4	Very high	20 Å²	20	21.7 Å²	21.7	9%	0.088	12%	0.119	C	C	.	.	H	α-helix	trans	-59.2	-45.3	176.7	173.1	-96.2	0	0	0	111.4	L81 G82 V87 F88 G89 L239 W393 Y427 C430 L434	L81-F85 WeakPolarHBondContact O-CB 3.23Å; L81-F85 PolarHBondContact O-N 3.37Å; G82-F85 PolarHBondContact O-N 3.31Å; F85-V87 PolarHBondContact O-N 2.87Å; F85-F88 PolarHBondContact O-N 3.44Å; F85-G89 PolarHBondContact O-N 3.2Å; F85-G89 VanDerWaalsContact O-N 3.07Å; F85-L239 HydrophobicContact CD1-CD1 4.01Å; F85-L239 HydrophobicContact CD1-CD2 3.44Å; F85-L239 VanDerWaalsContact CD1-CD2 3.44Å; F85-L239 HydrophobicContact CD1-CG 4.4Å; F85-L239 HydrophobicContact CE1-CD1 3.99Å; F85-L239 HydrophobicContact CE1-CD2 4.04Å; F85-L239 HydrophobicContact CG-CD2 4.36Å; F85-W393 HydrophobicContact CE1-CD2 4.32Å; F85-W393 AromaticContact CE1-CE3 3.8Å; F85-W393 HydrophobicContact CE1-CE3 3.8Å; F85-W393 HydrophobicContact CE1-CH2 4.49Å; F85-W393 AromaticContact CE1-CZ3 3.88Å; F85-W393 HydrophobicContact CE1-CZ3 3.88Å; F85-W393 HydrophobicContact CZ-CE3 4.3Å; F85-Y427 HydrophobicContact CD1-CE2 4.02Å; F85-Y427 HydrophobicContact CD2-CD2 4.01Å; F85-Y427 AromaticContact CD2-CE2 3.9Å; F85-Y427 HydrophobicContact CD2-CE2 3.9Å; F85-Y427 AromaticContact CE1-CE2 3.61Å; F85-Y427 HydrophobicContact CE1-CE2 3.61Å; F85-Y427 AromaticContact CE1-CZ 3.88Å; F85-Y427 AromaticContact CE2-CD2 3.67Å; F85-Y427 HydrophobicContact CE2-CD2 3.67Å; F85-Y427 AromaticContact CE2-CE2 3.43Å; F85-Y427 HydrophobicContact CE2-CE2 3.43Å; F85-Y427 VanDerWaalsContact CE2-CE2 3.43Å; F85-Y427 HydrophobicContact CE2-CG 4.38Å; F85-Y427 AromaticContact CE2-CZ 3.98Å; F85-Y427 HydrophobicContact CG-CE2 4.19Å; F85-Y427 HydrophobicContact CZ-CD2 4.02Å; F85-Y427 HydrophobicContact CZ-CE1 4.29Å; F85-Y427 AromaticContact CZ-CE2 3.29Å; F85-Y427 HydrophobicContact CZ-CE2 3.29Å; F85-Y427 AromaticContact CZ-CZ 3.46Å; F85-Y427 VanDerWaalsContact CZ-CZ 3.46Å; F85-Y427 WeakPolarHBondContact CZ-OH 3.34Å; F85-Y427 WeakPolarHBondContact O-CE2 3.31Å; F85-C430 HydrophobicContact CD2-CB 3.56Å; F85-C430 HydrophobicContact CE2-CB 3.42Å; F85-C430 VanDerWaalsContact CE2-CB 3.42Å; F85-L434 HydrophobicContact CE1-CD1 3.86Å; F85-L434 HydrophobicContact CE2-CD1 4.11Å; F85-L434 HydrophobicContact CZ-CD1 3.59Å
86	S	93.3	Very high	94.2	Very high	0 Å²	0	21.7 Å²	21.7	0%	0	12%	0.119	C	C	.	.	H	α-helix	trans	-66	-35.2	177.6	-58.5	0	0	0	0	112.8	G82 G83 I84 F88 G89 A90 Y242	G82-S86 PolarHBondContact O-N 3.19Å; G82-S86 PolarHBondContact O-OG 3.46Å; G83-S86 PolarHBondContact O-N 3.14Å; I84-S86 VanDerWaalsContact C-N 3.34Å; I84-S86 PolarHBondContact O-N 3.47Å; S86-F88 VanDerWaalsContact C-N 3.32Å; S86-F88 PolarHBondContact O-N 3.18Å; S86-G89 PolarHBondContact O-N 3.17Å; S86-A90 VanDerWaalsContact O-CB 3.26Å; S86-A90 WeakPolarHBondContact O-CB 3.36Å; S86-A90 PolarHBondContact O-N 3.23Å; S86-Y242 VanDerWaalsContact OG-CB 3.27Å; S86-Y242 WeakPolarHBondContact OG-CB 3.47Å
87	V	92.9	Very high	93.8	Very high	40 Å²	40	20.1 Å²	20.1	24%	0.242	11%	0.111	C	C	.	.	H	α-helix	trans	-59.3	-44.9	172.6	169	0	0	0	0	110.5	G83 I84 F85 G89 A90 L91 M270	G83-V87 VanDerWaalsContact O-CG2 3.31Å; G83-V87 WeakPolarHBondContact O-CG2 3.47Å; G83-V87 PolarHBondContact O-N 2.91Å; I84-V87 WeakPolarHBondContact O-CB 3.31Å; I84-V87 PolarHBondContact O-N 3.32Å; F85-V87 PolarHBondContact O-N 2.87Å; V87-G89 PolarHBondContact O-N 2.82Å; V87-A90 PolarHBondContact O-N 3.35Å; V87-L91 HydrophobicContact CG1-CD1 3.93Å; V87-L91 HydrophobicContact CG1-CG 4.36Å; V87-L91 WeakPolarHBondContact O-CB 3.24Å; V87-L91 VanDerWaalsContact O-CG 3.26Å; V87-L91 WeakPolarHBondContact O-CG 3.39Å; V87-L91 PolarHBondContact O-N 3.38Å; V87-M270 HydrophobicContact CG2-CB 3.61Å; V87-M270 HydrophobicContact CG2-CE 4.35Å; V87-M270 HydrophobicContact CG2-CG 4.32Å
88	F	93.3	Very high	93.5	Very high	44 Å²	44	17.5 Å²	17.5	19%	0.193	10%	0.095	C	C	.	.	H	α-helix	trans	-63.7	-43.5	-179.7	-80.1	34.8	0	0	0	111	I84 F85 S86 C92 F422 F423 V426 Y427	I84-F88 HydrophobicContact CG2-CD1 4.33Å; I84-F88 HydrophobicContact CG2-CE1 4.02Å; I84-F88 VanDerWaalsContact O-CD1 3.31Å; I84-F88 WeakPolarHBondContact O-CD1 3.43Å; I84-F88 PolarHBondContact O-N 2.85Å; I84-F88 VanDerWaalsContact O-N 3.11Å; F85-F88 PolarHBondContact O-N 3.44Å; S86-F88 VanDerWaalsContact C-N 3.32Å; S86-F88 PolarHBondContact O-N 3.18Å; F88-C92 PolarHBondContact O-N 3.39Å; F88-C92 VanDerWaalsContact O-N 3.11Å; F88-C92 PolarHBondContact O-SG 3.09Å; F88-F422 HydrophobicContact CE2-CE1 4.26Å; F88-F423 HydrophobicContact CD1-CD1 4.14Å; F88-F423 HydrophobicContact CD1-CE1 4.37Å; F88-F423 HydrophobicContact CD2-CD1 4.02Å; F88-F423 HydrophobicContact CE1-CD1 4.16Å; F88-F423 HydrophobicContact CE1-CE1 4.03Å; F88-F423 HydrophobicContact CE2-CD1 4.04Å; F88-F423 HydrophobicContact CE2-CE1 4.43Å; F88-F423 HydrophobicContact CG-CD1 4.06Å; F88-F423 HydrophobicContact CZ-CD1 4.12Å; F88-F423 HydrophobicContact CZ-CE1 4.07Å; F88-V426 HydrophobicContact CD2-CB 4.25Å; F88-V426 HydrophobicContact CD2-CG1 3.94Å; F88-V426 HydrophobicContact CE2-CB 4.25Å; F88-V426 HydrophobicContact CE2-CG1 3.86Å; F88-Y427 HydrophobicContact CB-CD2 4.06Å
89	G	92.8	Very high	93.2	Very high	0 Å²	0	18.3 Å²	18.3	0%	0	10%	0.1	C	C	.	.	H	α-helix	trans	-61.8	-48.3	175.6	0	0	0	0	0	112.4	F85 S86 V87 L91 C92 Y93 Y427	F85-G89 PolarHBondContact O-N 3.2Å; F85-G89 VanDerWaalsContact O-N 3.07Å; S86-G89 PolarHBondContact O-N 3.17Å; V87-G89 PolarHBondContact O-N 2.82Å; G89-L91 VanDerWaalsContact C-N 3.34Å; G89-L91 PolarHBondContact O-N 2.84Å; G89-C92 WeakPolarHBondContact O-CB 3.24Å; G89-C92 PolarHBondContact O-N 3.12Å; G89-C92 VanDerWaalsContact O-N 3.13Å; G89-Y93 PolarHBondContact O-N 3.18Å; G89-Y427 VanDerWaalsContact CA-CD2 3.45Å; G89-Y427 VanDerWaalsContact N-CD2 3.29Å
90	A	92.4	Very high	92.8	Very high	0 Å²	0	18.5 Å²	18.5	0%	0	10%	0.101	C	C	.	.	H	α-helix	trans	-64.2	-37.9	-178.8	0	0	0	0	0	112.4	S86 V87 Y93 A94 W245 I266 M270	S86-A90 VanDerWaalsContact O-CB 3.26Å; S86-A90 WeakPolarHBondContact O-CB 3.36Å; S86-A90 PolarHBondContact O-N 3.23Å; V87-A90 PolarHBondContact O-N 3.35Å; A90-Y93 PolarHBondContact O-N 2.65Å; A90-A94 PolarHBondContact O-N 2.67Å; A90-W245 VanDerWaalsContact CA-CE3 3.45Å; A90-W245 HydrophobicContact CB-CB 4.41Å; A90-W245 HydrophobicContact CB-CD2 3.75Å; A90-W245 HydrophobicContact CB-CE3 3.53Å; A90-W245 HydrophobicContact CB-CG 4.13Å; A90-W245 HydrophobicContact CB-CZ3 4.14Å; A90-I266 HydrophobicContact CB-CG2 3.37Å; A90-M270 HydrophobicContact CB-CG 4.15Å; A90-M270 HydrophobicContact CB-SD 4.28Å
91	L	92.2	Very high	92	Very high	39 Å²	39	20.8 Å²	20.8	20%	0.204	11%	0.112	C	C	.	.	H	α-helix	trans	-61.8	-47.3	171.6	-72.5	174.1	0	0	0	111.3	V87 G89 Y93 A94 E95 L419 F423	V87-L91 HydrophobicContact CG1-CD1 3.93Å; V87-L91 HydrophobicContact CG1-CG 4.36Å; V87-L91 WeakPolarHBondContact O-CB 3.24Å; V87-L91 VanDerWaalsContact O-CG 3.26Å; V87-L91 WeakPolarHBondContact O-CG 3.39Å; V87-L91 PolarHBondContact O-N 3.38Å; G89-L91 VanDerWaalsContact C-N 3.34Å; G89-L91 PolarHBondContact O-N 2.84Å; L91-Y93 VanDerWaalsContact C-N 3.26Å; L91-Y93 PolarHBondContact O-N 3.3Å; L91-A94 VanDerWaalsContact O-CB 3.32Å; L91-A94 WeakPolarHBondContact O-CB 3.36Å; L91-A94 PolarHBondContact O-N 3.04Å; L91-E95 PolarHBondContact O-N 2.87Å; L91-L419 HydrophobicContact CB-CD1 3.72Å; L91-L419 WeakPolarHBondContact O-CD1 3.26Å; L91-F423 HydrophobicContact CD1-CD1 4.49Å; L91-F423 HydrophobicContact CD1-CE1 4.38Å
92	C	94.1	Very high	91.2	Very high	0 Å²	0	21.6 Å²	21.6	0%	0	11%	0.112	C	C	.	.	H	α-helix	trans	-59.6	-38.5	177.1	-64.1	0	0	0	0	112.1	F88 G89 E95 L96 V400 L403 P424	F88-C92 PolarHBondContact O-N 3.39Å; F88-C92 VanDerWaalsContact O-N 3.11Å; F88-C92 PolarHBondContact O-SG 3.09Å; G89-C92 WeakPolarHBondContact O-CB 3.24Å; G89-C92 PolarHBondContact O-N 3.12Å; G89-C92 VanDerWaalsContact O-N 3.13Å; C92-E95 PolarHBondContact O-N 3.42Å; C92-L96 PolarHBondContact O-N 3.27Å; C92-V400 HydrophobicContact CB-CG1 4.02Å; C92-V400 HydrophobicContact CB-CG2 3.88Å; C92-L403 HydrophobicContact CB-CD2 4.25Å; C92-P424 VanDerWaalsContact SG-CA 3.59Å
93	Y	92.6	Very high	90.1	Very high	0 Å²	0	23 Å²	23	0%	0	12%	0.122	C	C	.	.	H	α-helix	trans	-72.3	-27.1	174.9	-93	-121.4	0	0	0	113.7	G89 A90 L91 E95 L96 G97 S106 Y109 W245 D246 N249 V396 S399 V400	G89-Y93 PolarHBondContact O-N 3.18Å; A90-Y93 PolarHBondContact O-N 2.65Å; L91-Y93 VanDerWaalsContact C-N 3.26Å; L91-Y93 PolarHBondContact O-N 3.3Å; Y93-E95 VanDerWaalsContact C-N 3.32Å; Y93-L96 HydrophobicContact CD2-CD1 4.36Å; Y93-L96 PolarHBondContact O-N 2.92Å; Y93-G97 PolarHBondContact O-N 3.47Å; Y93-S106 WeakPolarHBondContact CE1-OG 3.47Å; Y93-S106 PolarHBondContact OH-OG 3.41Å; Y93-Y109 HydrophobicContact CD1-CD2 4.4Å; Y93-Y109 AromaticContact CD1-CE2 3.75Å; Y93-Y109 HydrophobicContact CD1-CE2 3.75Å; Y93-Y109 HydrophobicContact CE1-CD2 4.13Å; Y93-Y109 AromaticContact CE1-CE2 3.85Å; Y93-Y109 HydrophobicContact CE1-CE2 3.85Å; Y93-Y109 HydrophobicContact CG-CE2 4.42Å; Y93-W245 VanDerWaalsContact CB-CZ3 3.48Å; Y93-W245 HydrophobicContact CD1-CH2 4.09Å; Y93-W245 AromaticContact CD1-CZ3 3.67Å; Y93-W245 HydrophobicContact CD1-CZ3 3.67Å; Y93-W245 AromaticContact CD2-CH2 3.54Å; Y93-W245 HydrophobicContact CD2-CH2 3.54Å; Y93-W245 AromaticContact CD2-CZ3 3.75Å; Y93-W245 HydrophobicContact CD2-CZ3 3.75Å; Y93-W245 HydrophobicContact CE1-CH2 4.37Å; Y93-W245 HydrophobicContact CE1-CZ3 4.31Å; Y93-W245 AromaticContact CE2-CH2 3.85Å; Y93-W245 HydrophobicContact CE2-CH2 3.85Å; Y93-W245 HydrophobicContact CE2-CZ3 4.37Å; Y93-W245 AromaticContact CG-CH2 3.68Å; Y93-W245 HydrophobicContact CG-CH2 3.68Å; Y93-W245 AromaticContact CG-CZ3 3.36Å; Y93-W245 HydrophobicContact CG-CZ3 3.36Å; Y93-D246 HydrophobicContact CD1-CB 3.97Å; Y93-D246 HydrophobicContact CE1-CB 4.04Å; Y93-N249 HydrophobicContact CD1-CB 4.43Å; Y93-N249 PolarHBondContact O-ND2 3.45Å; Y93-V396 HydrophobicContact CE2-CG1 3.64Å; Y93-V396 WeakPolarHBondContact OH-CA 3.41Å; Y93-S399 WeakPolarHBondContact OH-CB 3.46Å; Y93-S399 PolarHBondContact OH-OG 3.44Å; Y93-V400 HydrophobicContact CD2-CG2 4.1Å; Y93-V400 HydrophobicContact CE2-CG2 3.88Å
94	A	91.7	Very high	89.2	Confident	1 Å²	1	23.2 Å²	23.2	1%	0.008	12%	0.124	C	C	.	.	H	α-helix	trans	-64	-41	170.8	0	0	0	0	0	110.5	A90 L91 T98 P263 I266	A90-A94 PolarHBondContact O-N 2.67Å; L91-A94 VanDerWaalsContact O-CB 3.32Å; L91-A94 WeakPolarHBondContact O-CB 3.36Å; L91-A94 PolarHBondContact O-N 3.04Å; A94-T98 WeakPolarHBondContact O-CB 3.26Å; A94-T98 VanDerWaalsContact O-CG2 3.28Å; A94-T98 WeakPolarHBondContact O-CG2 3.46Å; A94-T98 PolarHBondContact O-N 3.44Å; A94-T98 VanDerWaalsContact O-N 3.07Å; A94-T98 PolarHBondContact O-OG1 3.49Å; A94-P263 HydrophobicContact CB-CB 4.29Å; A94-P263 HydrophobicContact CB-CG 4.3Å; A94-I266 HydrophobicContact CB-CD1 3.93Å
95	E	92.8	Very high	88.7	Confident	1 Å²	1	18.8 Å²	18.8	1%	0.005	10%	0.101	C	C	.	.	H	α-helix	trans	-64.5	-47	172.2	173.9	168.1	167.2	0	0	111.7	L91 C92 Y93 G97 T98 T99 L403 R407 R415 V417 L419	L91-E95 PolarHBondContact O-N 2.87Å; C92-E95 PolarHBondContact O-N 3.42Å; Y93-E95 VanDerWaalsContact C-N 3.32Å; E95-G97 PolarHBondContact O-N 3.12Å; E95-T98 PolarHBondContact O-N 3.36Å; E95-T98 PolarHBondContact O-OG1 3.45Å; E95-T98 VanDerWaalsContact O-OG1 3.1Å; E95-T99 VanDerWaalsContact O-CB 3.31Å; E95-T99 WeakPolarHBondContact O-CB 3.49Å; E95-T99 PolarHBondContact O-N 3.12Å; E95-T99 PolarHBondContact O-OG1 3.15Å; E95-L403 HydrophobicContact CB-CD2 4.37Å; E95-L403 HydrophobicContact CG-CD1 3.73Å; E95-L403 HydrophobicContact CG-CD2 4.24Å; E95-L403 WeakPolarHBondContact OE1-CD1 3.49Å; E95-R407 IonicContact OE1-CZ 2.95Å; E95-R407 IonicContact OE1-NE 2.93Å; E95-R407 PolarHBondContact OE1-NE 3.43Å; E95-R407 IonicContact OE1-NH1 3.91Å; E95-R407 IonicContact OE1-NH2 2.87Å; E95-R407 PolarHBondContact OE1-NH2 2.83Å; E95-R407 IonicContact OE2-CZ 3.97Å; E95-R407 IonicContact OE2-NH2 2.64Å; E95-R407 PolarHBondContact OE2-NH2 2.94Å; E95-R415 IonicContact OE1-NE 3.91Å; E95-V417 VanDerWaalsContact CG-O 3.31Å; E95-V417 WeakPolarHBondContact CG-O 3.45Å; E95-L419 HydrophobicContact CB-CD1 4.31Å; E95-L419 WeakPolarHBondContact OE2-CB 3.32Å; E95-L419 PolarHBondContact OE2-N 3.11Å
96	L	92.4	Very high	88.4	Confident	1 Å²	1	17.9 Å²	17.9	1%	0.005	10%	0.097	C	C	.	.	H	α-helix	trans	-60.4	-46.2	177.5	-77.4	169.1	0	0	0	112.3	C92 Y93 T98 T99 I100 Y109 L403	C92-L96 PolarHBondContact O-N 3.27Å; Y93-L96 HydrophobicContact CD2-CD1 4.36Å; Y93-L96 PolarHBondContact O-N 2.92Å; L96-T98 VanDerWaalsContact C-N 3.34Å; L96-T98 PolarHBondContact O-N 3.33Å; L96-T99 PolarHBondContact O-N 3.21Å; L96-T99 VanDerWaalsContact O-N 3.15Å; L96-I100 HydrophobicContact CD2-CD1 4.32Å; L96-I100 PolarHBondContact O-N 3.01Å; L96-Y109 HydrophobicContact CB-CD1 4.26Å; L96-Y109 HydrophobicContact CB-CD2 3.92Å; L96-Y109 HydrophobicContact CB-CE1 4.13Å; L96-Y109 HydrophobicContact CB-CE2 3.75Å; L96-Y109 HydrophobicContact CB-CG 4.17Å; L96-Y109 HydrophobicContact CD1-CD2 3.79Å; L96-Y109 HydrophobicContact CD1-CE2 4.27Å; L96-Y109 HydrophobicContact CD1-CG 4.24Å; L96-Y109 HydrophobicContact CD2-CG 4.46Å; L96-Y109 HydrophobicContact CG-CD2 4.37Å; L96-L403 HydrophobicContact CD1-CB 4.21Å; L96-L403 HydrophobicContact CD2-CB 3.79Å; L96-L403 HydrophobicContact CD2-CD1 3.69Å; L96-L403 HydrophobicContact CD2-CG 4.3Å; L96-L403 HydrophobicContact CG-CB 3.98Å; L96-L403 HydrophobicContact CG-CD1 3.95Å; L96-L403 HydrophobicContact CG-CD2 4.48Å; L96-L403 HydrophobicContact CG-CG 4.35Å
97	G	88.9	Confident	88.3	Confident	0 Å²	0	18 Å²	18	0%	0	10%	0.097	C	C	.	.	H	α-helix	trans	-69.6	-28.1	-178.3	0	0	0	0	0	114.2	Y93 E95 Y109	Y93-G97 PolarHBondContact O-N 3.47Å; E95-G97 PolarHBondContact O-N 3.12Å; G97-Y109 WeakPolarHBondContact CA-OH 3.46Å; G97-Y109 PolarHBondContact N-OH 3.43Å
98	T	90.2	Very high	88.1	Confident	7 Å²	7	16.3 Å²	16.3	4%	0.043	9%	0.088	C	C	.	.	H	α-helix	trans	-81.3	-20	172.3	54.4	0	0	0	0	113	A94 E95 L96 L262 P263 V417	A94-T98 WeakPolarHBondContact O-CB 3.26Å; A94-T98 VanDerWaalsContact O-CG2 3.28Å; A94-T98 WeakPolarHBondContact O-CG2 3.46Å; A94-T98 PolarHBondContact O-N 3.44Å; A94-T98 VanDerWaalsContact O-N 3.07Å; A94-T98 PolarHBondContact O-OG1 3.49Å; E95-T98 PolarHBondContact O-N 3.36Å; E95-T98 PolarHBondContact O-OG1 3.45Å; E95-T98 VanDerWaalsContact O-OG1 3.1Å; L96-T98 VanDerWaalsContact C-N 3.34Å; L96-T98 PolarHBondContact O-N 3.33Å; T98-L262 HydrophobicContact CG2-CD2 4.26Å; T98-P263 HydrophobicContact CG2-CG 4.35Å; T98-V417 HydrophobicContact CG2-CG2 3.91Å
99	T	90.6	Very high	88	Confident	18 Å²	18	14.3 Å²	14.3	11%	0.11	8%	0.079	C	C	.	.	H	α-helix	trans	-92.6	-35.8	178.7	-54.7	0	0	0	0	112.8	E95 L96 R413 R415	E95-T99 VanDerWaalsContact O-CB 3.31Å; E95-T99 WeakPolarHBondContact O-CB 3.49Å; E95-T99 PolarHBondContact O-N 3.12Å; E95-T99 PolarHBondContact O-OG1 3.15Å; L96-T99 PolarHBondContact O-N 3.21Å; L96-T99 VanDerWaalsContact O-N 3.15Å; T99-R413 HydrophobicContact CG2-CG 4.09Å; T99-R415 HydrophobicContact CG2-CG 3.99Å
100	I	88.1	Confident	88.1	Confident	4 Å²	4	14.3 Å²	14.3	2%	0.021	8%	0.079	C	C	.	.			trans	-121.8	89.5	-179.9	-55	167.1	0	0	0	106.8	L96 K102 Y109 E112 L406	L96-I100 HydrophobicContact CD2-CD1 4.32Å; L96-I100 PolarHBondContact O-N 3.01Å; I100-K102 HydrophobicContact CG2-CB 4.21Å; I100-K102 HydrophobicContact CG2-CG 4.39Å; I100-K102 PolarHBondContact O-N 3.49Å; I100-K102 VanDerWaalsContact O-N 3.13Å; I100-Y109 HydrophobicContact CB-CD1 3.94Å; I100-Y109 HydrophobicContact CB-CE1 4.02Å; I100-Y109 HydrophobicContact CD1-CD1 3.91Å; I100-Y109 HydrophobicContact CG2-CD1 4.09Å; I100-Y109 HydrophobicContact CG2-CE1 4.33Å; I100-E112 HydrophobicContact CD1-CB 3.99Å; I100-E112 HydrophobicContact CD1-CG 3.96Å; I100-E112 HydrophobicContact CG1-CG 4.3Å; I100-L406 HydrophobicContact CD1-CD1 3.98Å
101	T	80.4	Confident	88.1	Confident	78 Å²	78	16.2 Å²	16.2	48%	0.479	9%	0.089	S	C	.	.			trans	-81.3	17.2	-175.6	60.4	0	0	0	0	113.4	E253	T101-E253 WeakPolarHBondContact O-CG 3.28Å
102	K	78.9	Confident	88	Confident	107 Å²	107	17.1 Å²	17.1	47%	0.465	9%	0.092	S	C	.	.			trans	-77.9	137.3	177	-68	179	179.1	169.9	0	109.6	I100 A108 E112 E253	I100-K102 HydrophobicContact CG2-CB 4.21Å; I100-K102 HydrophobicContact CG2-CG 4.39Å; I100-K102 PolarHBondContact O-N 3.49Å; I100-K102 VanDerWaalsContact O-N 3.13Å; K102-A108 HydrophobicContact CB-CB 4.26Å; K102-E112 IonicContact NZ-OE2 2.9Å; K102-E112 PolarHBondContact NZ-OE2 2.83Å; K102-E253 WeakPolarHBondContact CA-OE1 3.45Å
103	S	72.5	Confident	88	Confident	30 Å²	30	17.6 Å²	17.6	21%	0.21	10%	0.096	C	C	.	.	T	Hydrogen-bonded Turn	trans	-61.4	142.1	172	-72.1	0	0	0	0	112.3	E253	S103-E253 PolarHBondContact N-OE1 3.2Å; S103-E253 PolarHBondContact OG-OE1 3.5Å; S103-E253 PolarHBondContact OG-OE2 3.07Å
104	G	74.4	Confident	88	Confident	5 Å²	5	21 Å²	21	5%	0.052	11%	0.111	C	C	.	.	T	Hydrogen-bonded Turn	trans	122.2	-1.5	178.2	0	0	0	0	0	116.1	S106 Y107	G104-S106 PolarHBondContact O-N 3.38Å; G104-Y107 PolarHBondContact O-N 3.11Å; G104-Y107 VanDerWaalsContact O-N 3.12Å
105	A	84.3	Confident	88	Confident	0 Å²	0	22.3 Å²	22.3	0%	0	13%	0.125	C	C	.	.	T	Hydrogen-bonded Turn	trans	44.9	-120.3	176.2	0	0	0	0	0	112.9	Y107 A108 Y109 N249 F250	A105-Y107 PolarHBondContact O-N 2.94Å; A105-Y107 VanDerWaalsContact O-N 3.12Å; A105-A108 PolarHBondContact O-N 3.49Å; A105-Y109 HydrophobicContact CB-CE2 4.48Å; A105-Y109 WeakPolarHBondContact O-CD1 3.47Å; A105-Y109 VanDerWaalsContact O-CD2 3.3Å; A105-Y109 WeakPolarHBondContact O-CD2 2.99Å; A105-Y109 PolarHBondContact O-N 3.29Å; A105-N249 HydrophobicContact CB-CB 3.74Å; A105-F250 HydrophobicContact CB-CD1 3.73Å; A105-F250 HydrophobicContact CB-CD2 3.59Å; A105-F250 HydrophobicContact CB-CE1 3.69Å; A105-F250 HydrophobicContact CB-CE2 3.57Å; A105-F250 HydrophobicContact CB-CG 3.7Å; A105-F250 HydrophobicContact CB-CZ 3.63Å
106	S	87.9	Confident	87.9	Confident	0 Å²	0	23.3 Å²	23.3	0%	0	14%	0.135	C	C	.	.	H	α-helix	trans	-51.4	-37.6	-177.5	-56.1	0	0	0	0	113.7	Y93 G104 I110	Y93-S106 WeakPolarHBondContact CE1-OG 3.47Å; Y93-S106 PolarHBondContact OH-OG 3.41Å; G104-S106 PolarHBondContact O-N 3.38Å; S106-I110 WeakPolarHBondContact O-CB 3.35Å; S106-I110 WeakPolarHBondContact O-CD1 3.02Å; S106-I110 VanDerWaalsContact O-CG1 3.22Å; S106-I110 WeakPolarHBondContact O-CG1 3.24Å; S106-I110 PolarHBondContact O-N 3.13Å
107	Y	90.2	Very high	87.9	Confident	2 Å²	2	26.5 Å²	26.5	1%	0.008	15%	0.149	C	C	.	.	H	α-helix	trans	-65.5	-49.6	177.3	168	-100.7	0	0	0	111.5	G104 A105 Y109 I110 L111 A119 L123 V340 E344 H346	G104-Y107 PolarHBondContact O-N 3.11Å; G104-Y107 VanDerWaalsContact O-N 3.12Å; A105-Y107 PolarHBondContact O-N 2.94Å; A105-Y107 VanDerWaalsContact O-N 3.12Å; Y107-Y109 VanDerWaalsContact C-N 3.33Å; Y107-Y109 PolarHBondContact O-N 3.3Å; Y107-I110 PolarHBondContact O-N 3.21Å; Y107-L111 HydrophobicContact CE1-CD2 4.24Å; Y107-L111 VanDerWaalsContact O-CB 3.3Å; Y107-L111 WeakPolarHBondContact O-CB 3.18Å; Y107-L111 PolarHBondContact O-N 2.85Å; Y107-A119 HydrophobicContact CD2-CB 4.04Å; Y107-A119 WeakPolarHBondContact CD2-O 3.47Å; Y107-A119 HydrophobicContact CE2-CB 3.75Å; Y107-A119 WeakPolarHBondContact CE2-O 3.45Å; Y107-L123 HydrophobicContact CD2-CB 3.9Å; Y107-L123 HydrophobicContact CD2-CD2 4.48Å; Y107-L123 HydrophobicContact CE2-CB 4.01Å; Y107-L123 HydrophobicContact CE2-CD2 3.96Å; Y107-L123 HydrophobicContact CE2-CG 4.48Å; Y107-V340 HydrophobicContact CD1-CG1 4.47Å; Y107-V340 HydrophobicContact CE1-CG1 4.29Å; Y107-E344 HydrophobicContact CE1-CG 4.11Å; Y107-E344 VanDerWaalsContact OH-CB 3.26Å; Y107-E344 WeakPolarHBondContact OH-CB 3.47Å; Y107-H346 AromaticContact CE2-ND1 3.74Å; Y107-H346 AromaticContact CZ-ND1 3.69Å; Y107-H346 PolarHBondContact OH-CE1 3.18Å; Y107-H346 PolarHBondContact OH-ND1 3.37Å
108	A	88.8	Confident	88.2	Confident	6 Å²	6	29 Å²	29	5%	0.05	16%	0.162	C	C	.	.	H	α-helix	trans	-64.6	-37.6	179.3	0	0	0	0	0	112	K102 A105 L111 E112	K102-A108 HydrophobicContact CB-CB 4.26Å; A105-A108 PolarHBondContact O-N 3.49Å; A108-L111 PolarHBondContact O-N 3.16Å; A108-E112 WeakPolarHBondContact O-CB 3.49Å; A108-E112 PolarHBondContact O-N 3.24Å
109	Y	92.1	Very high	88.3	Confident	1 Å²	1	28.7 Å²	28.7	0%	0.004	16%	0.16	C	C	.	.	H	α-helix	trans	-66.8	-43.4	177.9	-55.8	-24.7	0	0	0	112.3	Y93 L96 G97 I100 A105 Y107 S113 N249	Y93-Y109 HydrophobicContact CD1-CD2 4.4Å; Y93-Y109 AromaticContact CD1-CE2 3.75Å; Y93-Y109 HydrophobicContact CD1-CE2 3.75Å; Y93-Y109 HydrophobicContact CE1-CD2 4.13Å; Y93-Y109 AromaticContact CE1-CE2 3.85Å; Y93-Y109 HydrophobicContact CE1-CE2 3.85Å; Y93-Y109 HydrophobicContact CG-CE2 4.42Å; L96-Y109 HydrophobicContact CB-CD1 4.26Å; L96-Y109 HydrophobicContact CB-CD2 3.92Å; L96-Y109 HydrophobicContact CB-CE1 4.13Å; L96-Y109 HydrophobicContact CB-CE2 3.75Å; L96-Y109 HydrophobicContact CB-CG 4.17Å; L96-Y109 HydrophobicContact CD1-CD2 3.79Å; L96-Y109 HydrophobicContact CD1-CE2 4.27Å; L96-Y109 HydrophobicContact CD1-CG 4.24Å; L96-Y109 HydrophobicContact CD2-CG 4.46Å; L96-Y109 HydrophobicContact CG-CD2 4.37Å; G97-Y109 WeakPolarHBondContact CA-OH 3.46Å; G97-Y109 PolarHBondContact N-OH 3.43Å; I100-Y109 HydrophobicContact CB-CD1 3.94Å; I100-Y109 HydrophobicContact CB-CE1 4.02Å; I100-Y109 HydrophobicContact CD1-CD1 3.91Å; I100-Y109 HydrophobicContact CG2-CD1 4.09Å; I100-Y109 HydrophobicContact CG2-CE1 4.33Å; A105-Y109 HydrophobicContact CB-CE2 4.48Å; A105-Y109 WeakPolarHBondContact O-CD1 3.47Å; A105-Y109 VanDerWaalsContact O-CD2 3.3Å; A105-Y109 WeakPolarHBondContact O-CD2 2.99Å; A105-Y109 PolarHBondContact O-N 3.29Å; Y107-Y109 VanDerWaalsContact C-N 3.33Å; Y107-Y109 PolarHBondContact O-N 3.3Å; Y109-S113 WeakPolarHBondContact O-CB 3.48Å; Y109-S113 PolarHBondContact O-N 3.39Å; Y109-S113 PolarHBondContact O-OG 3.45Å; Y109-N249 WeakPolarHBondContact OH-CB 3.34Å; Y109-N249 PolarHBondContact OH-ND2 3.47Å
110	I	94	Very high	88.5	Confident	0 Å²	0	28 Å²	28	0%	0	16%	0.156	C	C	.	.	H	α-helix	trans	-67.8	-39	176.6	-68.3	166.6	0	0	0	110.4	S106 Y107 S113 F114 G115 L118 A119 R122 Y395 L398	S106-I110 WeakPolarHBondContact O-CB 3.35Å; S106-I110 WeakPolarHBondContact O-CD1 3.02Å; S106-I110 VanDerWaalsContact O-CG1 3.22Å; S106-I110 WeakPolarHBondContact O-CG1 3.24Å; S106-I110 PolarHBondContact O-N 3.13Å; Y107-I110 PolarHBondContact O-N 3.21Å; I110-S113 WeakPolarHBondContact CA-OG 3.27Å; I110-S113 PolarHBondContact O-N 3.16Å; I110-S113 PolarHBondContact O-OG 3.27Å; I110-F114 HydrophobicContact CG2-CD2 4.31Å; I110-F114 PolarHBondContact O-N 2.96Å; I110-G115 PolarHBondContact O-N 3.28Å; I110-L118 HydrophobicContact CG2-CB 3.69Å; I110-A119 HydrophobicContact CG2-CB 4.34Å; I110-R122 HydrophobicContact CD1-CB 4.04Å; I110-R122 HydrophobicContact CD1-CG 3.88Å; I110-Y395 HydrophobicContact CD1-CD1 4.42Å; I110-L398 HydrophobicContact CD1-CB 4.45Å; I110-L398 HydrophobicContact CD1-CD2 4.03Å; I110-L398 HydrophobicContact CD1-CG 4.28Å; I110-L398 HydrophobicContact CG1-CD2 4.4Å; I110-L398 HydrophobicContact CG1-CG 4.35Å; I110-L398 HydrophobicContact CG2-CD2 4.39Å
111	L	92.3	Very high	88.8	Confident	40 Å²	40	28.6 Å²	28.6	21%	0.209	16%	0.158	C	C	.	.	H	α-helix	trans	-59.8	-47.4	176.8	-177.7	61.1	0	0	0	111.9	Y107 A108 G115 A119	Y107-L111 HydrophobicContact CE1-CD2 4.24Å; Y107-L111 VanDerWaalsContact O-CB 3.3Å; Y107-L111 WeakPolarHBondContact O-CB 3.18Å; Y107-L111 PolarHBondContact O-N 2.85Å; A108-L111 PolarHBondContact O-N 3.16Å; L111-G115 VanDerWaalsContact O-CA 3.23Å; L111-G115 WeakPolarHBondContact O-CA 3.48Å; L111-G115 PolarHBondContact O-N 2.53Å; L111-G115 VanDerWaalsContact O-N 3.07Å; L111-A119 HydrophobicContact CB-CB 3.71Å; L111-A119 HydrophobicContact CD1-CB 3.79Å; L111-A119 HydrophobicContact CG-CB 4.34Å
112	E	91.4	Very high	89.4	Confident	58 Å²	58	25 Å²	25	27%	0.271	14%	0.136	S	C	.	.	H	α-helix	trans	-71.7	-30.7	-179.2	-170.6	80.5	-175.7	0	0	112.7	I100 K102 A108 R413	I100-E112 HydrophobicContact CD1-CB 3.99Å; I100-E112 HydrophobicContact CD1-CG 3.96Å; I100-E112 HydrophobicContact CG1-CG 4.3Å; K102-E112 IonicContact NZ-OE2 2.9Å; K102-E112 PolarHBondContact NZ-OE2 2.83Å; A108-E112 WeakPolarHBondContact O-CB 3.49Å; A108-E112 PolarHBondContact O-N 3.24Å; E112-R413 IonicContact OE1-CZ 3.4Å; E112-R413 IonicContact OE1-NH1 3Å; E112-R413 PolarHBondContact OE1-NH1 2.87Å; E112-R413 IonicContact OE1-NH2 2.95Å; E112-R413 PolarHBondContact OE1-NH2 3.03Å
113	S	93.1	Very high	90.1	Very high	10 Å²	10	20 Å²	20	7%	0.07	11%	0.114	C	C	.	.	H	α-helix	trans	-89.3	-45.2	-177	53.9	0	0	0	0	113.9	Y109 I110 Y405	Y109-S113 WeakPolarHBondContact O-CB 3.48Å; Y109-S113 PolarHBondContact O-N 3.39Å; Y109-S113 PolarHBondContact O-OG 3.45Å; I110-S113 WeakPolarHBondContact CA-OG 3.27Å; I110-S113 PolarHBondContact O-N 3.16Å; I110-S113 PolarHBondContact O-OG 3.27Å; S113-Y405 WeakPolarHBondContact O-CD1 3.24Å; S113-Y405 WeakPolarHBondContact O-CE1 3.38Å
114	F	93.9	Very high	91.1	Very high	72 Å²	72	21 Å²	21	32%	0.316	11%	0.114	S	C	.	.	H	α-helix	trans	-118.6	-4.5	-172.5	-58.3	-69	0	0	0	114.5	I110 L118 L398 A401 G402 Y405	I110-F114 HydrophobicContact CG2-CD2 4.31Å; I110-F114 PolarHBondContact O-N 2.96Å; F114-L118 HydrophobicContact CB-CB 4.26Å; F114-L118 HydrophobicContact CB-CD1 3.7Å; F114-L118 HydrophobicContact CB-CG 4.36Å; F114-L118 HydrophobicContact CD1-CD1 4.48Å; F114-L118 HydrophobicContact CD2-CD1 4.3Å; F114-L118 HydrophobicContact CG-CD1 3.94Å; F114-L398 HydrophobicContact CD2-CD1 4.18Å; F114-L398 HydrophobicContact CD2-CG 4.34Å; F114-L398 HydrophobicContact CE2-CD1 3.68Å; F114-L398 HydrophobicContact CE2-CG 4.04Å; F114-L398 WeakPolarHBondContact CE2-O 3.41Å; F114-L398 HydrophobicContact CZ-CD1 4.11Å; F114-A401 HydrophobicContact CZ-CB 4.47Å; F114-G402 VanDerWaalsContact CE2-CA 3.5Å; F114-Y405 HydrophobicContact CE1-CG 4.26Å
115	G	91.4	Very high	92.1	Very high	29 Å²	29	20.8 Å²	20.8	30%	0.299	11%	0.111	S	C	.	.			trans	88.4	-177.5	177	0	0	0	0	0	115.1	I110 L111 F117 A119	I110-G115 PolarHBondContact O-N 3.28Å; L111-G115 VanDerWaalsContact O-CA 3.23Å; L111-G115 WeakPolarHBondContact O-CA 3.48Å; L111-G115 PolarHBondContact O-N 2.53Å; L111-G115 VanDerWaalsContact O-N 3.07Å; G115-F117 PolarHBondContact O-N 3.25Å; G115-A119 PolarHBondContact O-N 2.79Å
116	G	90.3	Very high	92.4	Very high	21 Å²	21	20.8 Å²	20.8	22%	0.216	11%	0.111	C	C	.	.	H	α-helix	trans	-63.7	-31.4	-167.7	0	0	0	0	0	115.6	F120	G116-F120 WeakPolarHBondContact O-CB 3.36Å; G116-F120 PolarHBondContact O-N 2.86Å
117	F	93.2	Very high	92.6	Very high	68 Å²	68	21 Å²	21	30%	0.298	11%	0.112	S	C	.	.	H	α-helix	trans	-63.8	-56.1	-178	175.5	-109.7	0	0	0	112.4	G115 A119 F120 I121 V457 Y460 Y461	G115-F117 PolarHBondContact O-N 3.25Å; F117-A119 VanDerWaalsContact C-N 3.29Å; F117-A119 PolarHBondContact O-N 3.11Å; F117-F120 PolarHBondContact O-N 2.83Å; F117-I121 HydrophobicContact CD2-CG1 4.5Å; F117-I121 HydrophobicContact CE1-CG1 4.45Å; F117-I121 HydrophobicContact CE2-CD1 4.28Å; F117-I121 HydrophobicContact CE2-CG1 4.15Å; F117-I121 HydrophobicContact CZ-CD1 4.43Å; F117-I121 HydrophobicContact CZ-CG1 4.13Å; F117-I121 WeakPolarHBondContact O-CG1 3.41Å; F117-I121 PolarHBondContact O-N 3.23Å; F117-V457 HydrophobicContact CE2-CG1 4.33Å; F117-V457 HydrophobicContact CE2-CG2 4.34Å; F117-V457 HydrophobicContact CZ-CG1 4.38Å; F117-V457 HydrophobicContact CZ-CG2 4.01Å; F117-Y460 HydrophobicContact CB-CE1 4.05Å; F117-Y460 AromaticContact CD2-CD1 3.49Å; F117-Y460 HydrophobicContact CD2-CD1 3.49Å; F117-Y460 VanDerWaalsContact CD2-CD1 3.49Å; F117-Y460 HydrophobicContact CD2-CD2 4.43Å; F117-Y460 AromaticContact CD2-CE1 3.69Å; F117-Y460 HydrophobicContact CD2-CE1 3.69Å; F117-Y460 AromaticContact CD2-CG 3.87Å; F117-Y460 HydrophobicContact CD2-CG 3.87Å; F117-Y460 HydrophobicContact CE2-CD1 4.12Å; F117-Y460 HydrophobicContact CE2-CG 4.41Å; F117-Y460 HydrophobicContact CG-CE1 4.35Å; F117-Y460 PolarHBondContact N-OH 3.14Å; F117-Y461 HydrophobicContact CE2-CE2 4.25Å
118	L	94.1	Very high	92.7	Very high	54 Å²	54	22.8 Å²	22.8	28%	0.283	12%	0.122	S	C	.	.	H	α-helix	trans	-67.6	-32.8	179.8	-69.2	-172.6	0	0	0	111.9	I110 F114 F120 I121 R122 L398	I110-L118 HydrophobicContact CG2-CB 3.69Å; F114-L118 HydrophobicContact CB-CB 4.26Å; F114-L118 HydrophobicContact CB-CD1 3.7Å; F114-L118 HydrophobicContact CB-CG 4.36Å; F114-L118 HydrophobicContact CD1-CD1 4.48Å; F114-L118 HydrophobicContact CD2-CD1 4.3Å; F114-L118 HydrophobicContact CG-CD1 3.94Å; L118-F120 VanDerWaalsContact C-N 3.35Å; L118-I121 PolarHBondContact O-N 3.4Å; L118-R122 WeakPolarHBondContact O-CB 3.47Å; L118-R122 PolarHBondContact O-N 3.21Å; L118-L398 HydrophobicContact CD1-CD1 4.49Å; L118-L398 HydrophobicContact CD1-CD2 4.25Å
119	A	93.1	Very high	92.9	Very high	0 Å²	0	22.6 Å²	22.6	0%	0	12%	0.12	C	C	.	.	H	α-helix	trans	-62.5	-42	173.5	0	0	0	0	0	111.8	Y107 I110 L111 G115 F117 R122 L123	Y107-A119 HydrophobicContact CD2-CB 4.04Å; Y107-A119 WeakPolarHBondContact CD2-O 3.47Å; Y107-A119 HydrophobicContact CE2-CB 3.75Å; Y107-A119 WeakPolarHBondContact CE2-O 3.45Å; I110-A119 HydrophobicContact CG2-CB 4.34Å; L111-A119 HydrophobicContact CB-CB 3.71Å; L111-A119 HydrophobicContact CD1-CB 3.79Å; L111-A119 HydrophobicContact CG-CB 4.34Å; G115-A119 PolarHBondContact O-N 2.79Å; F117-A119 VanDerWaalsContact C-N 3.29Å; F117-A119 PolarHBondContact O-N 3.11Å; A119-R122 WeakPolarHBondContact O-CB 3.28Å; A119-R122 PolarHBondContact O-N 3.01Å; A119-L123 WeakPolarHBondContact O-CB 3.43Å; A119-L123 PolarHBondContact O-N 3.17Å
120	F	93.9	Very high	92.9	Very high	4 Å²	4	22.5 Å²	22.5	2%	0.018	12%	0.119	C	C	.	.	H	α-helix	trans	-63.5	-46.5	174	173.6	-92.4	0	0	0	111.9	G116 F117 L118 R122 L123 W124 H346 G456 V459 Y460 I464	G116-F120 WeakPolarHBondContact O-CB 3.36Å; G116-F120 PolarHBondContact O-N 2.86Å; F117-F120 PolarHBondContact O-N 2.83Å; L118-F120 VanDerWaalsContact C-N 3.35Å; F120-R122 VanDerWaalsContact C-N 3.28Å; F120-R122 PolarHBondContact O-N 2.91Å; F120-L123 WeakPolarHBondContact O-CB 3.45Å; F120-L123 PolarHBondContact O-N 3.02Å; F120-L123 VanDerWaalsContact O-N 3.08Å; F120-W124 HydrophobicContact CD1-CB 4.48Å; F120-W124 HydrophobicContact CE1-CB 4.08Å; F120-W124 HydrophobicContact CE1-CD2 4.32Å; F120-W124 HydrophobicContact CE1-CE3 4.3Å; F120-W124 HydrophobicContact CE1-CG 4.26Å; F120-W124 HydrophobicContact CE2-CE3 4.23Å; F120-W124 HydrophobicContact CZ-CB 4.28Å; F120-W124 HydrophobicContact CZ-CD2 4.05Å; F120-W124 AromaticContact CZ-CE3 3.59Å; F120-W124 HydrophobicContact CZ-CE3 3.59Å; F120-W124 HydrophobicContact CZ-CG 4.38Å; F120-W124 HydrophobicContact CZ-CZ3 4.25Å; F120-W124 VanDerWaalsContact O-CB 3.25Å; F120-W124 WeakPolarHBondContact O-CB 3.49Å; F120-W124 PolarHBondContact O-N 3.46Å; F120-H346 HydrophobicContact CD2-CB 4.04Å; F120-H346 WeakPolarHBondContact CD2-O 3.35Å; F120-H346 VanDerWaalsContact CE2-O 3.25Å; F120-H346 WeakPolarHBondContact CE2-O 3.24Å; F120-G456 VanDerWaalsContact CE1-O 3.26Å; F120-G456 WeakPolarHBondContact CE1-O 3.39Å; F120-V459 HydrophobicContact CZ-CB 4.3Å; F120-V459 HydrophobicContact CZ-CG1 3.98Å; F120-Y460 HydrophobicContact CB-CD2 3.52Å; F120-Y460 HydrophobicContact CB-CE2 3.85Å; F120-Y460 AromaticContact CD1-CD2 3.66Å; F120-Y460 HydrophobicContact CD1-CD2 3.66Å; F120-Y460 HydrophobicContact CD1-CG 4.08Å; F120-Y460 HydrophobicContact CD2-CD2 4.19Å; F120-Y460 HydrophobicContact CE1-CD2 4.45Å; F120-Y460 AromaticContact CG-CD2 3.5Å; F120-Y460 HydrophobicContact CG-CD2 3.5Å; F120-Y460 HydrophobicContact CG-CE2 4.29Å; F120-Y460 HydrophobicContact CG-CG 4.37Å; F120-I464 HydrophobicContact CD2-CD1 3.2Å; F120-I464 HydrophobicContact CE2-CD1 3.39Å; F120-I464 HydrophobicContact CG-CD1 3.91Å; F120-I464 HydrophobicContact CZ-CD1 4.24Å
121	I	94.9	Very high	92.8	Very high	15 Å²	15	23.8 Å²	23.8	8%	0.077	13%	0.125	C	C	.	.	H	α-helix	trans	-61.4	-39.4	179.8	-63.2	-64.4	0	0	0	111.1	F117 L118 T125 Y395 A453 V457	F117-I121 HydrophobicContact CD2-CG1 4.5Å; F117-I121 HydrophobicContact CE1-CG1 4.45Å; F117-I121 HydrophobicContact CE2-CD1 4.28Å; F117-I121 HydrophobicContact CE2-CG1 4.15Å; F117-I121 HydrophobicContact CZ-CD1 4.43Å; F117-I121 HydrophobicContact CZ-CG1 4.13Å; F117-I121 WeakPolarHBondContact O-CG1 3.41Å; F117-I121 PolarHBondContact O-N 3.23Å; L118-I121 PolarHBondContact O-N 3.4Å; I121-T125 WeakPolarHBondContact O-CB 3.34Å; I121-T125 PolarHBondContact O-N 3.39Å; I121-T125 PolarHBondContact O-OG1 3.01Å; I121-Y395 WeakPolarHBondContact CG2-OH 3.45Å; I121-Y395 PolarHBondContact O-OH 2.98Å; I121-A453 HydrophobicContact CG2-CB 4.22Å; I121-V457 HydrophobicContact CD1-CG2 3.89Å
122	R	93.4	Very high	92.8	Very high	4 Å²	4	21.9 Å²	21.9	2%	0.015	12%	0.115	C	C	.	.	H	α-helix	trans	-58.6	-48.4	170.6	169	64.1	-175.9	72	-7.1	112.3	I110 L118 A119 F120 S126 Y395	I110-R122 HydrophobicContact CD1-CB 4.04Å; I110-R122 HydrophobicContact CD1-CG 3.88Å; L118-R122 WeakPolarHBondContact O-CB 3.47Å; L118-R122 PolarHBondContact O-N 3.21Å; A119-R122 WeakPolarHBondContact O-CB 3.28Å; A119-R122 PolarHBondContact O-N 3.01Å; F120-R122 VanDerWaalsContact C-N 3.28Å; F120-R122 PolarHBondContact O-N 2.91Å; R122-S126 PolarHBondContact NH1-OG 3.38Å; R122-S126 PolarHBondContact NH2-OG 3.26Å; R122-S126 PolarHBondContact O-N 3.49Å; R122-Y395 HydrophobicContact CB-CD1 3.93Å; R122-Y395 HydrophobicContact CB-CE1 3.98Å; R122-Y395 HydrophobicContact CB-CG 4.46Å; R122-Y395 VanDerWaalsContact CD-CD1 3.4Å; R122-Y395 HydrophobicContact CG-CD1 4.28Å; R122-Y395 HydrophobicContact CG-CG 4.37Å
123	L	92.8	Very high	92.9	Very high	0 Å²	0	19.1 Å²	19.1	0%	0	10%	0.103	C	C	.	.	H	α-helix	trans	-65.3	-47.6	-178.7	179.3	63.6	0	0	0	111	Y107 A119 F120 T125 S126 I127 L337 H346 L347	Y107-L123 HydrophobicContact CD2-CB 3.9Å; Y107-L123 HydrophobicContact CD2-CD2 4.48Å; Y107-L123 HydrophobicContact CE2-CB 4.01Å; Y107-L123 HydrophobicContact CE2-CD2 3.96Å; Y107-L123 HydrophobicContact CE2-CG 4.48Å; A119-L123 WeakPolarHBondContact O-CB 3.43Å; A119-L123 PolarHBondContact O-N 3.17Å; F120-L123 WeakPolarHBondContact O-CB 3.45Å; F120-L123 PolarHBondContact O-N 3.02Å; F120-L123 VanDerWaalsContact O-N 3.08Å; L123-T125 VanDerWaalsContact C-N 3.35Å; L123-T125 PolarHBondContact O-N 3.27Å; L123-S126 WeakPolarHBondContact O-CB 3.17Å; L123-S126 PolarHBondContact O-N 3.5Å; L123-S126 VanDerWaalsContact O-N 3.12Å; L123-I127 HydrophobicContact CD1-CD1 3.87Å; L123-I127 HydrophobicContact CD1-CG1 4.43Å; L123-I127 HydrophobicContact CG-CD1 3.75Å; L123-I127 WeakPolarHBondContact O-CD1 3.27Å; L123-I127 VanDerWaalsContact O-CG1 3.26Å; L123-I127 WeakPolarHBondContact O-CG1 3.27Å; L123-I127 PolarHBondContact O-N 3.08Å; L123-L337 HydrophobicContact CD1-CD1 3.99Å; L123-L337 HydrophobicContact CD1-CD2 4.4Å; L123-L337 HydrophobicContact CD1-CG 3.86Å; L123-H346 HydrophobicContact CD2-CB 3.85Å; L123-L347 HydrophobicContact CD1-CD1 4.36Å; L123-L347 HydrophobicContact CD2-CD1 3.9Å; L123-L347 HydrophobicContact CD2-CD2 4.4Å; L123-L347 HydrophobicContact CD2-CG 3.85Å; L123-L347 HydrophobicContact CG-CD1 4.23Å; L123-L347 HydrophobicContact CG-CG 4.46Å
124	W	94.3	Very high	92.9	Very high	53 Å²	53	19.3 Å²	19.3	20%	0.201	10%	0.104	C	C	.	.	H	α-helix	trans	-54.2	-48.9	176.4	-174.7	-103	0	0	0	111.8	F120 S126 I127 L128 I452 S455 G456 V459	F120-W124 HydrophobicContact CD1-CB 4.48Å; F120-W124 HydrophobicContact CE1-CB 4.08Å; F120-W124 HydrophobicContact CE1-CD2 4.32Å; F120-W124 HydrophobicContact CE1-CE3 4.3Å; F120-W124 HydrophobicContact CE1-CG 4.26Å; F120-W124 HydrophobicContact CE2-CE3 4.23Å; F120-W124 HydrophobicContact CZ-CB 4.28Å; F120-W124 HydrophobicContact CZ-CD2 4.05Å; F120-W124 AromaticContact CZ-CE3 3.59Å; F120-W124 HydrophobicContact CZ-CE3 3.59Å; F120-W124 HydrophobicContact CZ-CG 4.38Å; F120-W124 HydrophobicContact CZ-CZ3 4.25Å; F120-W124 VanDerWaalsContact O-CB 3.25Å; F120-W124 WeakPolarHBondContact O-CB 3.49Å; F120-W124 PolarHBondContact O-N 3.46Å; W124-S126 VanDerWaalsContact C-N 3.34Å; W124-S126 PolarHBondContact O-N 3.33Å; W124-I127 PolarHBondContact O-N 3.49Å; W124-L128 HydrophobicContact CD2-CD1 3.95Å; W124-L128 HydrophobicContact CG-CD1 4.35Å; W124-L128 HydrophobicContact CH2-CD1 4.25Å; W124-L128 HydrophobicContact CZ2-CD1 3.52Å; W124-L128 WeakPolarHBondContact O-CB 3.45Å; W124-L128 PolarHBondContact O-N 3.48Å; W124-I452 PolarHBondContact NE1-O 3.22Å; W124-S455 PolarHBondContact NE1-OG 3Å; W124-G456 VanDerWaalsContact CD1-CA 3.46Å; W124-V459 HydrophobicContact CH2-CB 4.34Å; W124-V459 HydrophobicContact CH2-CG1 4.01Å; W124-V459 HydrophobicContact CH2-CG2 3.93Å; W124-V459 HydrophobicContact CZ2-CG2 3.96Å; W124-V459 HydrophobicContact CZ3-CG1 3.94Å
125	T	93.9	Very high	92.9	Very high	0 Å²	0	15.9 Å²	15.9	0%	0	9%	0.089	C	C	.	.	H	α-helix	trans	-69.5	-32.5	179.1	-47.6	0	0	0	0	112.1	I121 L123 L129 I130 Y395	I121-T125 WeakPolarHBondContact O-CB 3.34Å; I121-T125 PolarHBondContact O-N 3.39Å; I121-T125 PolarHBondContact O-OG1 3.01Å; L123-T125 VanDerWaalsContact C-N 3.35Å; L123-T125 PolarHBondContact O-N 3.27Å; T125-L129 HydrophobicContact CG2-CB 4.36Å; T125-L129 HydrophobicContact CG2-CD2 4.33Å; T125-L129 WeakPolarHBondContact O-CB 3.29Å; T125-L129 PolarHBondContact O-N 2.79Å; T125-I130 HydrophobicContact CG2-CG1 4.49Å; T125-I130 PolarHBondContact O-N 3.4Å; T125-I130 VanDerWaalsContact O-N 3.13Å; T125-Y395 HydrophobicContact CG2-CE2 3.69Å; T125-Y395 PolarHBondContact OG1-OH 3.04Å
126	S	91.9	Very high	93.1	Very high	0 Å²	0	14.5 Å²	14.5	0%	0	7%	0.074	C	C	.	.	I	π-helix	trans	-61.6	-49.2	173.8	-118.7	0	0	0	0	111.6	R122 L123 W124 L128 I130 E131	R122-S126 PolarHBondContact NH1-OG 3.38Å; R122-S126 PolarHBondContact NH2-OG 3.26Å; R122-S126 PolarHBondContact O-N 3.49Å; L123-S126 WeakPolarHBondContact O-CB 3.17Å; L123-S126 PolarHBondContact O-N 3.5Å; L123-S126 VanDerWaalsContact O-N 3.12Å; W124-S126 VanDerWaalsContact C-N 3.34Å; W124-S126 PolarHBondContact O-N 3.33Å; S126-L128 PolarHBondContact O-N 3.31Å; S126-I130 PolarHBondContact O-N 2.96Å; S126-E131 WeakPolarHBondContact O-CG 3.37Å; S126-E131 PolarHBondContact O-N 3.45Å; S126-E131 PolarHBondContact OG-OE1 3.29Å; S126-E131 VanDerWaalsContact OG-OE1 3.06Å
127	I	91.3	Very high	93.3	Very high	5 Å²	5	13.5 Å²	13.5	3%	0.026	6%	0.064	C	C	.	.	I	π-helix	trans	-65	-41.5	-175.2	-69	161.5	0	0	0	111.6	L123 W124 P132 F338 L347 F367	L123-I127 HydrophobicContact CD1-CD1 3.87Å; L123-I127 HydrophobicContact CD1-CG1 4.43Å; L123-I127 HydrophobicContact CG-CD1 3.75Å; L123-I127 WeakPolarHBondContact O-CD1 3.27Å; L123-I127 VanDerWaalsContact O-CG1 3.26Å; L123-I127 WeakPolarHBondContact O-CG1 3.27Å; L123-I127 PolarHBondContact O-N 3.08Å; W124-I127 PolarHBondContact O-N 3.49Å; I127-P132 WeakPolarHBondContact O-CG 3.38Å; I127-F338 HydrophobicContact CB-CE1 4.04Å; I127-F338 HydrophobicContact CB-CZ 4.2Å; I127-F338 HydrophobicContact CD1-CD1 4.11Å; I127-F338 HydrophobicContact CD1-CE1 4.4Å; I127-F338 HydrophobicContact CG1-CD1 3.4Å; I127-F338 VanDerWaalsContact CG1-CD1 3.4Å; I127-F338 HydrophobicContact CG1-CE1 3.25Å; I127-F338 HydrophobicContact CG1-CE2 4.49Å; I127-F338 HydrophobicContact CG1-CG 4.18Å; I127-F338 HydrophobicContact CG1-CZ 3.84Å; I127-F338 HydrophobicContact CG2-CE1 4.47Å; I127-F338 HydrophobicContact CG2-CE2 4.47Å; I127-F338 HydrophobicContact CG2-CZ 4.24Å; I127-L347 HydrophobicContact CD1-CD1 3.49Å; I127-L347 VanDerWaalsContact CD1-CD1 3.49Å; I127-L347 HydrophobicContact CD1-CD2 3.53Å; I127-L347 HydrophobicContact CD1-CG 4.09Å; I127-F367 HydrophobicContact CG2-CD1 4.17Å; I127-F367 HydrophobicContact CG2-CE1 3.25Å; I127-F367 HydrophobicContact CG2-CZ 3.84Å
128	L	92.5	Very high	93.3	Very high	39 Å²	39	10.9 Å²	10.9	20%	0.204	5%	0.053	C	C	.	.	I	π-helix	trans	-90.9	-20.6	-173	-66.5	-175.9	0	0	0	114.4	W124 S126 F367 M371 F375 I452	W124-L128 HydrophobicContact CD2-CD1 3.95Å; W124-L128 HydrophobicContact CG-CD1 4.35Å; W124-L128 HydrophobicContact CH2-CD1 4.25Å; W124-L128 HydrophobicContact CZ2-CD1 3.52Å; W124-L128 WeakPolarHBondContact O-CB 3.45Å; W124-L128 PolarHBondContact O-N 3.48Å; S126-L128 PolarHBondContact O-N 3.31Å; L128-F367 HydrophobicContact CD2-CZ 4.48Å; L128-M371 HydrophobicContact CD2-CE 4.02Å; L128-M371 HydrophobicContact CD2-SD 4.38Å; L128-M371 WeakPolarHBondContact O-CE 3.46Å; L128-F375 WeakPolarHBondContact O-CE2 3.42Å; L128-F375 WeakPolarHBondContact O-CZ 3.49Å; L128-I452 HydrophobicContact CB-CG2 3.99Å; L128-I452 HydrophobicContact CD1-CG2 4.34Å
129	L	92.4	Very high	93.4	Very high	1 Å²	1	8.3 Å²	8.3	1%	0.005	4%	0.039	C	C	.	.	I	π-helix	trans	-137.3	-55.4	-169.8	179.9	142.3	0	0	0	113.5	T125 A133 F375 Y387 S391 I452	T125-L129 HydrophobicContact CG2-CB 4.36Å; T125-L129 HydrophobicContact CG2-CD2 4.33Å; T125-L129 WeakPolarHBondContact O-CB 3.29Å; T125-L129 PolarHBondContact O-N 2.79Å; L129-A133 WeakPolarHBondContact O-CB 3.44Å; L129-A133 PolarHBondContact O-N 3.31Å; L129-F375 HydrophobicContact CB-CZ 4.49Å; L129-Y387 WeakPolarHBondContact CD2-O 3.43Å; L129-S391 WeakPolarHBondContact CD2-OG 3.3Å; L129-I452 HydrophobicContact CB-CD1 4.46Å; L129-I452 HydrophobicContact CB-CG2 4.36Å; L129-I452 HydrophobicContact CD1-CD1 3.5Å
130	I	92.3	Very high	93.5	Very high	0 Å²	0	8.4 Å²	8.4	0%	0	4%	0.04	C	C	.	.	I	π-helix	trans	-67.3	-56.2	-170.5	-56.4	174.3	0	0	0	111.6	T125 S126 S134 F388 Y392 Y395	T125-I130 HydrophobicContact CG2-CG1 4.49Å; T125-I130 PolarHBondContact O-N 3.4Å; T125-I130 VanDerWaalsContact O-N 3.13Å; S126-I130 PolarHBondContact O-N 2.96Å; I130-S134 WeakPolarHBondContact O-CB 3.14Å; I130-S134 PolarHBondContact O-N 2.99Å; I130-S134 VanDerWaalsContact O-N 3.1Å; I130-F388 HydrophobicContact CB-CD2 4.44Å; I130-F388 HydrophobicContact CG2-CD2 3.51Å; I130-F388 HydrophobicContact CG2-CE2 3.43Å; I130-F388 VanDerWaalsContact CG2-CE2 3.43Å; I130-F388 WeakPolarHBondContact O-CD2 3.31Å; I130-Y392 HydrophobicContact CG2-CD2 4.06Å; I130-Y395 HydrophobicContact CD1-CD2 4Å; I130-Y395 HydrophobicContact CD1-CE2 4.43Å
131	E	91.6	Very high	93.4	Very high	27 Å²	27	8.3 Å²	8.3	13%	0.126	4%	0.04	C	C	.	.	H	α-helix	trans	-65.7	-47.1	-176.3	-49.4	-55.6	149.1	0	0	111.9	S126 A133 S134 Q135 A334 F338	S126-E131 WeakPolarHBondContact O-CG 3.37Å; S126-E131 PolarHBondContact O-N 3.45Å; S126-E131 PolarHBondContact OG-OE1 3.29Å; S126-E131 VanDerWaalsContact OG-OE1 3.06Å; E131-A133 PolarHBondContact O-N 2.95Å; E131-S134 PolarHBondContact O-N 3.43Å; E131-Q135 VanDerWaalsContact O-CG 3.25Å; E131-Q135 WeakPolarHBondContact O-CG 3.47Å; E131-Q135 PolarHBondContact O-N 2.88Å; E131-A334 HydrophobicContact CB-CB 3.91Å; E131-A334 HydrophobicContact CG-CB 3.84Å; E131-F338 HydrophobicContact CB-CZ 4.47Å; E131-F338 HydrophobicContact CG-CE1 4.18Å; E131-F338 HydrophobicContact CG-CZ 4.31Å
132	P	93.6	Very high	93.3	Very high	0 Å²	0	9 Å²	9	0%	0	4%	0.043	C	C	.	.	H	α-helix	trans	-63.9	-40.7	179.4	-24	36.6	0	0	0	113.4	I127 Q135 A136 M371 F375	I127-P132 WeakPolarHBondContact O-CG 3.38Å; P132-Q135 PolarHBondContact O-N 3Å; P132-A136 WeakPolarHBondContact O-CB 3.43Å; P132-A136 PolarHBondContact O-N 3.4Å; P132-M371 HydrophobicContact CB-CB 3.87Å; P132-M371 HydrophobicContact CG-CB 3.53Å; P132-M371 HydrophobicContact CG-CE 4.33Å; P132-M371 HydrophobicContact CG-CG 4.39Å; P132-F375 HydrophobicContact CB-CB 4.42Å; P132-F375 HydrophobicContact CB-CD2 3.54Å; P132-F375 HydrophobicContact CB-CE2 3.87Å; P132-F375 HydrophobicContact CB-CG 3.92Å; P132-F375 HydrophobicContact CG-CE2 4.46Å
133	A	94	Very high	93.3	Very high	0 Å²	0	8.9 Å²	8.9	0%	0	4%	0.042	C	C	.	.	H	α-helix	trans	-64.5	-44	178.4	0	0	0	0	0	111.4	L129 E131 Q135 A136 V137 F375 L384 F388	L129-A133 WeakPolarHBondContact O-CB 3.44Å; L129-A133 PolarHBondContact O-N 3.31Å; E131-A133 PolarHBondContact O-N 2.95Å; A133-Q135 PolarHBondContact O-N 3.46Å; A133-A136 PolarHBondContact O-N 3.25Å; A133-V137 WeakPolarHBondContact O-CG2 3.13Å; A133-V137 PolarHBondContact O-N 2.88Å; A133-F375 HydrophobicContact CB-CD1 3.8Å; A133-F375 HydrophobicContact CB-CE1 3.89Å; A133-L384 HydrophobicContact CB-CD2 4.33Å; A133-F388 HydrophobicContact CB-CB 4.32Å
134	S	92.8	Very high	93.3	Very high	13 Å²	13	9.9 Å²	9.9	9%	0.091	5%	0.048	C	C	.	.	H	α-helix	trans	-59.7	-46.7	176.2	-175.8	0	0	0	0	111.6	I130 E131 A136 V137 I138	I130-S134 WeakPolarHBondContact O-CB 3.14Å; I130-S134 PolarHBondContact O-N 2.99Å; I130-S134 VanDerWaalsContact O-N 3.1Å; E131-S134 PolarHBondContact O-N 3.43Å; S134-A136 VanDerWaalsContact C-N 3.35Å; S134-A136 PolarHBondContact O-N 3.22Å; S134-V137 PolarHBondContact O-N 3Å; S134-I138 WeakPolarHBondContact O-CD1 3.41Å; S134-I138 VanDerWaalsContact O-CG1 3.23Å; S134-I138 WeakPolarHBondContact O-CG1 3.44Å; S134-I138 PolarHBondContact O-N 3.47Å
135	Q	94.2	Very high	93.1	Very high	0 Å²	0	7.4 Å²	7.4	0%	0	4%	0.038	C	C	.	.	H	α-helix	trans	-63.6	-38.5	177.9	-68.8	165.7	27.1	0	0	112.5	E131 P132 A133 I138 S139 L327 S330 I331 N368	E131-Q135 VanDerWaalsContact O-CG 3.25Å; E131-Q135 WeakPolarHBondContact O-CG 3.47Å; E131-Q135 PolarHBondContact O-N 2.88Å; P132-Q135 PolarHBondContact O-N 3Å; A133-Q135 PolarHBondContact O-N 3.46Å; Q135-I138 PolarHBondContact O-N 2.71Å; Q135-S139 VanDerWaalsContact O-CB 3.31Å; Q135-S139 WeakPolarHBondContact O-CB 3.45Å; Q135-S139 PolarHBondContact O-N 2.86Å; Q135-S139 PolarHBondContact O-OG 3.2Å; Q135-L327 HydrophobicContact CB-CD1 3.71Å; Q135-L327 HydrophobicContact CG-CD1 3.92Å; Q135-S330 VanDerWaalsContact CG-OG 3.31Å; Q135-S330 WeakPolarHBondContact CG-OG 3.49Å; Q135-I331 HydrophobicContact CG-CG1 4.42Å; Q135-N368 PolarHBondContact NE2-ND2 3.29Å; Q135-N368 PolarHBondContact NE2-OD1 3.17Å; Q135-N368 PolarHBondContact OE1-ND2 2.81Å; Q135-N368 PolarHBondContact OE1-OD1 3.38Å
136	A	95.5	Very high	92.9	Very high	0 Å²	0	10.3 Å²	10.3	0%	0	5%	0.053	C	C	.	.	H	α-helix	trans	-63.2	-46	174	0	0	0	0	0	111.4	P132 A133 S134 I138 S139 L140 F375 L376 L384	P132-A136 WeakPolarHBondContact O-CB 3.43Å; P132-A136 PolarHBondContact O-N 3.4Å; A133-A136 PolarHBondContact O-N 3.25Å; S134-A136 VanDerWaalsContact C-N 3.35Å; S134-A136 PolarHBondContact O-N 3.22Å; A136-I138 PolarHBondContact O-N 3.49Å; A136-S139 WeakPolarHBondContact CA-OG 3.44Å; A136-S139 PolarHBondContact O-N 3.2Å; A136-S139 PolarHBondContact O-OG 2.94Å; A136-L140 WeakPolarHBondContact O-CB 3.46Å; A136-L140 VanDerWaalsContact O-CG 3.23Å; A136-L140 WeakPolarHBondContact O-CG 3.37Å; A136-L140 PolarHBondContact O-N 2.99Å; A136-F375 HydrophobicContact CB-CB 3.76Å; A136-L376 HydrophobicContact CB-CD2 4.14Å; A136-L384 HydrophobicContact CB-CD1 3.86Å; A136-L384 HydrophobicContact CB-CD2 4.49Å
137	V	94.4	Very high	92.8	Very high	0 Å²	0	10.6 Å²	10.6	0%	0	6%	0.055	C	C	.	.	H	α-helix	trans	-60	-47.6	176.1	173.9	0	0	0	0	111.2	A133 S134 S139 L140 T141 F240 V381 L384 I385	A133-V137 WeakPolarHBondContact O-CG2 3.13Å; A133-V137 PolarHBondContact O-N 2.88Å; S134-V137 PolarHBondContact O-N 3Å; V137-S139 PolarHBondContact O-N 3.43Å; V137-L140 PolarHBondContact O-N 3.24Å; V137-T141 WeakPolarHBondContact O-CB 3.29Å; V137-T141 PolarHBondContact O-N 2.86Å; V137-T141 PolarHBondContact O-OG1 3.22Å; V137-F240 HydrophobicContact CB-CZ 3.95Å; V137-F240 HydrophobicContact CG1-CE1 3.64Å; V137-F240 HydrophobicContact CG1-CE2 4.41Å; V137-F240 HydrophobicContact CG1-CZ 3.45Å; V137-F240 VanDerWaalsContact CG1-CZ 3.45Å; V137-V381 HydrophobicContact CB-CG1 4.35Å; V137-V381 HydrophobicContact CG1-CG1 3.83Å; V137-V381 HydrophobicContact CG2-CG1 4.09Å; V137-L384 HydrophobicContact CG2-CB 3.45Å; V137-L384 VanDerWaalsContact CG2-CB 3.45Å; V137-L384 HydrophobicContact CG2-CD1 4.14Å; V137-L384 HydrophobicContact CG2-CG 4.45Å; V137-I385 HydrophobicContact CG1-CD1 4.31Å; V137-I385 HydrophobicContact CG1-CG1 4.08Å; V137-I385 HydrophobicContact CG2-CG1 3.92Å
138	I	93.1	Very high	92.6	Very high	13 Å²	13	11.5 Å²	11.5	7%	0.067	6%	0.059	C	C	.	.	H	α-helix	trans	-63.2	-44.1	-179	-60.4	159.5	0	0	0	111.1	S56 S134 Q135 A136 T141 F142 C323 L327	S56-I138 VanDerWaalsContact OG-CG1 3.29Å; S56-I138 WeakPolarHBondContact OG-CG1 3.25Å; S134-I138 WeakPolarHBondContact O-CD1 3.41Å; S134-I138 VanDerWaalsContact O-CG1 3.23Å; S134-I138 WeakPolarHBondContact O-CG1 3.44Å; S134-I138 PolarHBondContact O-N 3.47Å; Q135-I138 PolarHBondContact O-N 2.71Å; A136-I138 PolarHBondContact O-N 3.49Å; I138-T141 WeakPolarHBondContact O-CB 3.05Å; I138-T141 PolarHBondContact O-N 3.12Å; I138-F142 PolarHBondContact O-N 2.91Å; I138-C323 HydrophobicContact CG2-CB 4.06Å; I138-C323 WeakPolarHBondContact CG2-O 3.2Å; I138-L327 HydrophobicContact CB-CD1 4.45Å; I138-L327 HydrophobicContact CG2-CB 3.78Å
139	S	95.3	Very high	92.1	Very high	0 Å²	0	11.9 Å²	11.9	0%	0	7%	0.068	C	C	.	.	H	α-helix	trans	-70.5	-36.6	-179.6	59.8	0	0	0	0	113.3	Q135 A136 V137 T141 F142 A143 A165	Q135-S139 VanDerWaalsContact O-CB 3.31Å; Q135-S139 WeakPolarHBondContact O-CB 3.45Å; Q135-S139 PolarHBondContact O-N 2.86Å; Q135-S139 PolarHBondContact O-OG 3.2Å; A136-S139 WeakPolarHBondContact CA-OG 3.44Å; A136-S139 PolarHBondContact O-N 3.2Å; A136-S139 PolarHBondContact O-OG 2.94Å; V137-S139 PolarHBondContact O-N 3.43Å; S139-T141 VanDerWaalsContact C-N 3.34Å; S139-F142 WeakPolarHBondContact O-CB 3.17Å; S139-F142 PolarHBondContact O-N 2.93Å; S139-A143 PolarHBondContact O-N 3.3Å; S139-A165 WeakPolarHBondContact O-CB 3.29Å
140	L	94.7	Very high	91.8	Very high	2 Å²	2	21.4 Å²	21.4	1%	0.01	10%	0.104	C	C	.	.	H	α-helix	trans	-65.2	-40	171.4	-71.8	169.5	0	0	0	111	A136 V137 A143 N144 I161 R162 A165 L376 V381 L384	A136-L140 WeakPolarHBondContact O-CB 3.46Å; A136-L140 VanDerWaalsContact O-CG 3.23Å; A136-L140 WeakPolarHBondContact O-CG 3.37Å; A136-L140 PolarHBondContact O-N 2.99Å; V137-L140 PolarHBondContact O-N 3.24Å; L140-A143 PolarHBondContact O-N 2.91Å; L140-N144 WeakPolarHBondContact O-CB 3.31Å; L140-N144 PolarHBondContact O-N 3.24Å; L140-N144 PolarHBondContact O-ND2 3.19Å; L140-I161 HydrophobicContact CD2-CG2 3.99Å; L140-R162 HydrophobicContact CD2-CG 4.06Å; L140-A165 HydrophobicContact CD2-CB 4.16Å; L140-L376 HydrophobicContact CD1-CD2 4.2Å; L140-L376 HydrophobicContact CD2-CD2 3.91Å; L140-L376 HydrophobicContact CG-CD2 3.73Å; L140-V381 HydrophobicContact CB-CG2 4.24Å; L140-V381 HydrophobicContact CD1-CG2 3.93Å; L140-L384 HydrophobicContact CD1-CD1 3.84Å
141	T	92.5	Very high	91.4	Very high	3 Å²	3	25.8 Å²	25.8	2%	0.018	12%	0.121	C	C	.	.	H	α-helix	trans	-61.2	-46.7	174	-49.8	0	0	0	0	110.9	F59 V60 V137 I138 S139 A143 N144 Y145	F59-T141 HydrophobicContact CB-CG2 4.49Å; V60-T141 HydrophobicContact CG2-CG2 3.55Å; V60-T141 WeakPolarHBondContact CG2-OG1 3.41Å; V137-T141 WeakPolarHBondContact O-CB 3.29Å; V137-T141 PolarHBondContact O-N 2.86Å; V137-T141 PolarHBondContact O-OG1 3.22Å; I138-T141 WeakPolarHBondContact O-CB 3.05Å; I138-T141 PolarHBondContact O-N 3.12Å; S139-T141 VanDerWaalsContact C-N 3.34Å; T141-A143 VanDerWaalsContact C-N 3.3Å; T141-A143 PolarHBondContact O-N 3.33Å; T141-N144 PolarHBondContact O-N 3.22Å; T141-Y145 HydrophobicContact CG2-CD2 3.72Å; T141-Y145 HydrophobicContact CG2-CE2 3.79Å; T141-Y145 WeakPolarHBondContact O-CB 3.5Å; T141-Y145 VanDerWaalsContact O-CD2 3.26Å; T141-Y145 WeakPolarHBondContact O-CD2 3.43Å; T141-Y145 PolarHBondContact O-N 2.96Å
142	F	93.1	Very high	90.6	Very high	30 Å²	30	27.9 Å²	27.9	13%	0.132	14%	0.137	C	C	.	.	H	α-helix	trans	-52.5	-49.7	174.5	167.5	-95.7	0	0	0	111.5	I138 S139 L146 I164 C168 A320 C323 Y324	I138-F142 PolarHBondContact O-N 2.91Å; S139-F142 WeakPolarHBondContact O-CB 3.17Å; S139-F142 PolarHBondContact O-N 2.93Å; F142-L146 HydrophobicContact CE1-CD2 4.39Å; F142-L146 HydrophobicContact CZ-CD2 4.24Å; F142-L146 WeakPolarHBondContact O-CB 3.4Å; F142-L146 PolarHBondContact O-N 2.97Å; F142-L146 VanDerWaalsContact O-N 3.15Å; F142-I164 HydrophobicContact CD1-CG2 4.28Å; F142-I164 HydrophobicContact CE1-CG2 3.87Å; F142-C168 HydrophobicContact CD1-CB 3.82Å; F142-C168 HydrophobicContact CE1-CB 3.76Å; F142-A320 HydrophobicContact CD2-CB 3.88Å; F142-A320 VanDerWaalsContact CD2-O 3.3Å; F142-A320 WeakPolarHBondContact CD2-O 3.41Å; F142-A320 HydrophobicContact CE2-CB 3.88Å; F142-C323 HydrophobicContact CB-CB 3.66Å; F142-C323 HydrophobicContact CD2-CB 4.43Å; F142-Y324 HydrophobicContact CE2-CD2 4.46Å
143	A	94.2	Very high	89.8	Confident	0 Å²	0	34.4 Å²	34.4	0%	0	18%	0.177	C	C	.	.	H	α-helix	trans	-69.9	-44	-176.8	0	0	0	0	0	112.5	S139 L140 T141 Y145 L146 V147 I161 I164 A165	S139-A143 PolarHBondContact O-N 3.3Å; L140-A143 PolarHBondContact O-N 2.91Å; T141-A143 VanDerWaalsContact C-N 3.3Å; T141-A143 PolarHBondContact O-N 3.33Å; A143-Y145 PolarHBondContact O-N 3.49Å; A143-L146 PolarHBondContact O-N 3.32Å; A143-V147 WeakPolarHBondContact O-CB 3.45Å; A143-V147 VanDerWaalsContact O-CG2 3.24Å; A143-V147 WeakPolarHBondContact O-CG2 3.42Å; A143-V147 PolarHBondContact O-N 3.46Å; A143-I161 HydrophobicContact CB-CB 4.42Å; A143-I161 HydrophobicContact CB-CG2 3.79Å; A143-I161 WeakPolarHBondContact CB-O 3.14Å; A143-I164 HydrophobicContact CB-CB 3.98Å; A143-I164 HydrophobicContact CB-CG2 3.8Å; A143-A165 HydrophobicContact CB-CB 4.01Å
144	N	91.3	Very high	89.3	Confident	22 Å²	22	37.8 Å²	37.8	12%	0.118	20%	0.2	C	C	.	.	H	α-helix	trans	-55.8	-51	176.5	-82.3	-27.3	0	0	0	111.2	L140 T141 L146 V147 E148 I161	L140-N144 WeakPolarHBondContact O-CB 3.31Å; L140-N144 PolarHBondContact O-N 3.24Å; L140-N144 PolarHBondContact O-ND2 3.19Å; T141-N144 PolarHBondContact O-N 3.22Å; N144-L146 VanDerWaalsContact C-N 3.3Å; N144-L146 PolarHBondContact O-N 3.42Å; N144-V147 PolarHBondContact O-N 3.01Å; N144-E148 WeakPolarHBondContact O-CB 3.43Å; N144-E148 PolarHBondContact O-N 3.24Å; N144-I161 WeakPolarHBondContact OD1-CD1 3.43Å; N144-I161 WeakPolarHBondContact OD1-CG1 3.49Å; N144-I161 VanDerWaalsContact OD1-CG2 3.24Å; N144-I161 WeakPolarHBondContact OD1-CG2 3.14Å
145	Y	90.4	Very high	88.7	Confident	1 Å²	1	44.9 Å²	44.9	0%	0.004	23%	0.231	C	C	.	.	H	α-helix	trans	-63.7	-35.5	-179.5	-88	-100.3	0	0	0	113.2	F59 T141 A143 A298 V299 A300 V301 P316 V319	F59-Y145 HydrophobicContact CB-CE1 4.49Å; F59-Y145 HydrophobicContact CB-CE2 3.99Å; F59-Y145 WeakPolarHBondContact CB-OH 3.12Å; F59-Y145 PolarHBondContact O-OH 3.4Å; T141-Y145 HydrophobicContact CG2-CD2 3.72Å; T141-Y145 HydrophobicContact CG2-CE2 3.79Å; T141-Y145 WeakPolarHBondContact O-CB 3.5Å; T141-Y145 VanDerWaalsContact O-CD2 3.26Å; T141-Y145 WeakPolarHBondContact O-CD2 3.43Å; T141-Y145 PolarHBondContact O-N 2.96Å; A143-Y145 PolarHBondContact O-N 3.49Å; Y145-A298 HydrophobicContact CD1-CB 3.95Å; Y145-A298 HydrophobicContact CD2-CB 3.74Å; Y145-A298 HydrophobicContact CE1-CB 3.76Å; Y145-A298 HydrophobicContact CE2-CB 3.55Å; Y145-A298 HydrophobicContact CG-CB 3.94Å; Y145-V299 PolarHBondContact OH-N 3.43Å; Y145-A300 HydrophobicContact CE1-CB 3.84Å; Y145-A300 PolarHBondContact OH-N 2.91Å; Y145-V301 HydrophobicContact CD1-CG2 3.52Å; Y145-V301 HydrophobicContact CE1-CG2 3.8Å; Y145-V301 HydrophobicContact CG-CG2 4.41Å; Y145-P316 VanDerWaalsContact O-CB 3.29Å; Y145-P316 WeakPolarHBondContact O-CB 3.21Å; Y145-V319 HydrophobicContact CD1-CB 3.47Å; Y145-V319 VanDerWaalsContact CD1-CB 3.47Å; Y145-V319 HydrophobicContact CD1-CG1 3.32Å; Y145-V319 HydrophobicContact CD1-CG2 3.85Å; Y145-V319 HydrophobicContact CD2-CG1 3.93Å; Y145-V319 HydrophobicContact CE1-CB 3.86Å; Y145-V319 HydrophobicContact CE1-CG1 3.57Å; Y145-V319 HydrophobicContact CE1-CG2 3.76Å; Y145-V319 HydrophobicContact CE2-CG1 4.15Å; Y145-V319 HydrophobicContact CG-CB 4.04Å; Y145-V319 HydrophobicContact CG-CG1 3.51Å
146	L	90.3	Very high	88.3	Confident	61 Å²	61	45.7 Å²	45.7	32%	0.319	24%	0.237	S	C	.	.	H	α-helix	trans	-72	-45.3	177.4	-173.3	63.1	0	0	0	111.5	F142 A143 N144 A149 I164	F142-L146 HydrophobicContact CE1-CD2 4.39Å; F142-L146 HydrophobicContact CZ-CD2 4.24Å; F142-L146 WeakPolarHBondContact O-CB 3.4Å; F142-L146 PolarHBondContact O-N 2.97Å; F142-L146 VanDerWaalsContact O-N 3.15Å; A143-L146 PolarHBondContact O-N 3.32Å; N144-L146 VanDerWaalsContact C-N 3.3Å; N144-L146 PolarHBondContact O-N 3.42Å; L146-A149 WeakPolarHBondContact O-CB 3.48Å; L146-I164 HydrophobicContact CD2-CG2 4.28Å
147	V	90.4	Very high	88.1	Confident	6 Å²	6	48.3 Å²	48.3	4%	0.036	25%	0.254	C	S	.	.	H	α-helix	trans	-72.2	-42.2	-177.1	-178.7	0	0	0	0	110.8	A143 N144 A149 W150 Y151 P156 I161 I164	A143-V147 WeakPolarHBondContact O-CB 3.45Å; A143-V147 VanDerWaalsContact O-CG2 3.24Å; A143-V147 WeakPolarHBondContact O-CG2 3.42Å; A143-V147 PolarHBondContact O-N 3.46Å; N144-V147 PolarHBondContact O-N 3.01Å; V147-A149 PolarHBondContact O-N 2.98Å; V147-A149 VanDerWaalsContact O-N 3.13Å; V147-W150 WeakPolarHBondContact O-CA 3.42Å; V147-W150 WeakPolarHBondContact O-CB 3.44Å; V147-W150 PolarHBondContact O-N 3.14Å; V147-Y151 HydrophobicContact CG1-CD2 3.58Å; V147-Y151 HydrophobicContact CG1-CE2 3.78Å; V147-Y151 WeakPolarHBondContact O-CD2 3.39Å; V147-Y151 PolarHBondContact O-N 3.29Å; V147-P156 HydrophobicContact CB-CB 4.23Å; V147-P156 HydrophobicContact CG1-CB 3.5Å; V147-I161 HydrophobicContact CB-CG1 4.45Å; V147-I161 HydrophobicContact CG2-CG1 4.36Å; V147-I164 HydrophobicContact CG2-CD1 3.41Å; V147-I164 VanDerWaalsContact CG2-CD1 3.41Å
148	E	85.3	Confident	87.8	Confident	23 Å²	23	53 Å²	53	11%	0.107	27%	0.272	C	S	.	.	H	α-helix	trans	-60.6	-27.3	-178.8	-167.4	165.6	154.8	0	0	112.7	N144 W150 Y151 A298 V301	N144-E148 WeakPolarHBondContact O-CB 3.43Å; N144-E148 PolarHBondContact O-N 3.24Å; E148-W150 PolarHBondContact O-N 3.1Å; E148-Y151 CarbonylContact O-C 3.53Å; E148-Y151 PolarHBondContact O-N 2.93Å; E148-Y151 VanDerWaalsContact O-N 3.16Å; E148-A298 HydrophobicContact CB-CB 4.45Å; E148-A298 HydrophobicContact CG-CB 4.49Å; E148-A298 WeakPolarHBondContact OE2-CB 3.26Å; E148-A298 PolarHBondContact OE2-N 3.2Å; E148-A298 VanDerWaalsContact OE2-N 3.09Å; E148-V301 HydrophobicContact CG-CG1 4.4Å
149	A	83.2	Confident	87.8	Confident	47 Å²	47	57.7 Å²	57.7	39%	0.388	30%	0.298	S	S	.	.	T	Hydrogen-bonded Turn	trans	-59.8	-29.2	171.6	0	0	0	0	0	113.5	L146 V147 P316	L146-A149 WeakPolarHBondContact O-CB 3.48Å; V147-A149 PolarHBondContact O-N 2.98Å; V147-A149 VanDerWaalsContact O-N 3.13Å; A149-P316 HydrophobicContact CB-CB 3.86Å; A149-P316 HydrophobicContact CB-CG 3.84Å
150	W	85.5	Confident	87.7	Confident	201 Å²	201	59.2 Å²	59.2	76%	0.761	31%	0.31	S	S	*	.	T	Hydrogen-bonded Turn	trans	-94.2	-16.6	177.6	-56.5	92.9	0	0	0	113.2	V147 E148 P152	V147-W150 WeakPolarHBondContact O-CA 3.42Å; V147-W150 WeakPolarHBondContact O-CB 3.44Å; V147-W150 PolarHBondContact O-N 3.14Å; E148-W150 PolarHBondContact O-N 3.1Å; W150-P152 VanDerWaalsContact O-CD 3.28Å; W150-P152 WeakPolarHBondContact O-CD 3.23Å
151	Y	84.9	Confident	87.6	Confident	92 Å²	92	59.7 Å²	59.7	36%	0.361	31%	0.313	S	S	.	.			trans	-119.5	63.2	-179	-68.3	-101.3	0	0	0	111.1	V147 E148 T153 C154 P157	V147-Y151 HydrophobicContact CG1-CD2 3.58Å; V147-Y151 HydrophobicContact CG1-CE2 3.78Å; V147-Y151 WeakPolarHBondContact O-CD2 3.39Å; V147-Y151 PolarHBondContact O-N 3.29Å; E148-Y151 CarbonylContact O-C 3.53Å; E148-Y151 PolarHBondContact O-N 2.93Å; E148-Y151 VanDerWaalsContact O-N 3.16Å; Y151-T153 VanDerWaalsContact C-N 3.28Å; Y151-T153 PolarHBondContact O-N 3.35Å; Y151-C154 VanDerWaalsContact CD1-SG 3.59Å; Y151-P157 HydrophobicContact CE1-CG 4.15Å
152	P	73.8	Confident	87.7	Confident	72 Å²	72	61.2 Å²	61.2	47%	0.468	32%	0.318	S	S	.	.	S	Bend	trans	-72.2	-16.4	-172.7	29.5	-36.9	0	0	0	114.6	W150	W150-P152 VanDerWaalsContact O-CD 3.28Å; W150-P152 WeakPolarHBondContact O-CD 3.23Å
153	T	77.4	Confident	87.8	Confident	137 Å²	137	65.6 Å²	65.6	84%	0.84	34%	0.342	S	S	*	.	S	Bend	trans	-122.9	-4.3	-173.4	52	0	0	0	0	113.8	Y151	Y151-T153 VanDerWaalsContact C-N 3.28Å; Y151-T153 PolarHBondContact O-N 3.35Å
154	C	83.1	Confident	87.9	Confident	70 Å²	70	68.2 Å²	68.2	47%	0.473	36%	0.356	S	S	.	.	S	Bend	trans	-139.1	155.9	-176.8	44.4	0	0	0	0	110	Y151	Y151-C154 VanDerWaalsContact CD1-SG 3.59Å
155	Q	80.1	Confident	88.2	Confident	162 Å²	162	67.2 Å²	67.2	76%	0.757	35%	0.35	S	S	*	.	P	Polyproline II helix	trans	-68.4	133.5	178.9	-75.7	-178.6	-27.2	0	0	110.3
156	P	85.6	Confident	88.5	Confident	18 Å²	18	68.3 Å²	68.3	12%	0.117	36%	0.359	C	S	.	.	P	Polyproline II helix	trans	-63.1	141.5	177.7	26.1	-34.6	0	0	0	110.9	V147 Y158 I161	V147-P156 HydrophobicContact CB-CB 4.23Å; V147-P156 HydrophobicContact CG1-CB 3.5Å; P156-Y158 PolarHBondContact O-N 3.23Å; P156-I161 HydrophobicContact CB-CD1 3.85Å; P156-I161 HydrophobicContact CB-CG1 4.33Å; P156-I161 HydrophobicContact CG-CD1 3.78Å
157	P	90.9	Very high	88.8	Confident	55 Å²	55	68.1 Å²	68.1	36%	0.357	37%	0.367	S	S	.	.	P	Polyproline II helix	trans	-62.3	129.7	178.8	-21.6	31.8	0	0	0	112.1	Y151 D159 A160 I161	Y151-P157 HydrophobicContact CE1-CG 4.15Å; P157-D159 VanDerWaalsContact C-N 3.32Å; P157-D159 PolarHBondContact O-N 3.35Å; P157-A160 HydrophobicContact CB-CB 4.05Å; P157-A160 HydrophobicContact CG-CB 4.47Å; P157-A160 WeakPolarHBondContact O-CB 3.26Å; P157-A160 PolarHBondContact O-N 2.96Å; P157-A160 VanDerWaalsContact O-N 3.11Å; P157-I161 PolarHBondContact O-N 3.24Å
158	Y	89.3	Confident	89	Confident	97 Å²	97	68.2 Å²	68.2	38%	0.38	37%	0.367	S	S	.	.	H	α-helix	trans	-52.6	-45.4	-179.4	177.8	-87.7	0	0	0	113.2	P156 R162 E379	P156-Y158 PolarHBondContact O-N 3.23Å; Y158-R162 PolarHBondContact O-N 3.28Å; Y158-R162 PolarHBondContact OH-NE 3.44Å; Y158-R162 VanDerWaalsContact OH-NE 3.12Å; Y158-R162 PolarHBondContact OH-NH1 3.33Å; Y158-R162 PolarHBondContact OH-NH2 3.35Å; Y158-E379 HydrophobicContact CE2-CB 4.39Å; Y158-E379 WeakPolarHBondContact OH-CG 3.47Å
159	D	92.3	Very high	89.5	Confident	113 Å²	113	67.1 Å²	67.1	60%	0.604	36%	0.362	S	S	*	.	H	α-helix	trans	-68.4	-36	-178.7	-62.5	-37.8	0	0	0	112.2	P157 I161 R162 L163	P157-D159 VanDerWaalsContact C-N 3.32Å; P157-D159 PolarHBondContact O-N 3.35Å; D159-I161 PolarHBondContact O-N 2.94Å; D159-R162 PolarHBondContact O-N 3.47Å; D159-L163 WeakPolarHBondContact O-CB 3.33Å; D159-L163 VanDerWaalsContact O-CG 3.27Å; D159-L163 WeakPolarHBondContact O-CG 3.35Å; D159-L163 PolarHBondContact O-N 3.41Å
160	A	93.3	Very high	90.1	Very high	31 Å²	31	67.8 Å²	67.8	26%	0.256	36%	0.364	S	S	.	.	H	α-helix	trans	-64.1	-43.9	-179.5	0	0	0	0	0	111.1	P157 R162 L163 I164	P157-A160 HydrophobicContact CB-CB 4.05Å; P157-A160 HydrophobicContact CG-CB 4.47Å; P157-A160 WeakPolarHBondContact O-CB 3.26Å; P157-A160 PolarHBondContact O-N 2.96Å; P157-A160 VanDerWaalsContact O-N 3.11Å; A160-R162 PolarHBondContact O-N 3.27Å; A160-L163 PolarHBondContact O-N 2.84Å; A160-I164 WeakPolarHBondContact O-CB 3.37Å; A160-I164 WeakPolarHBondContact O-CD1 3.32Å; A160-I164 VanDerWaalsContact O-CG1 3.23Å; A160-I164 WeakPolarHBondContact O-CG1 3.46Å; A160-I164 PolarHBondContact O-N 3.42Å
161	I	93	Very high	90.4	Very high	13 Å²	13	63 Å²	63	7%	0.067	35%	0.351	C	S	.	.	H	α-helix	trans	-58.8	-48.4	177.1	-66.6	156.2	0	0	0	110.2	L140 A143 N144 V147 P156 P157 D159 I164 A165	L140-I161 HydrophobicContact CD2-CG2 3.99Å; A143-I161 HydrophobicContact CB-CB 4.42Å; A143-I161 HydrophobicContact CB-CG2 3.79Å; A143-I161 WeakPolarHBondContact CB-O 3.14Å; N144-I161 WeakPolarHBondContact OD1-CD1 3.43Å; N144-I161 WeakPolarHBondContact OD1-CG1 3.49Å; N144-I161 VanDerWaalsContact OD1-CG2 3.24Å; N144-I161 WeakPolarHBondContact OD1-CG2 3.14Å; V147-I161 HydrophobicContact CB-CG1 4.45Å; V147-I161 HydrophobicContact CG2-CG1 4.36Å; P156-I161 HydrophobicContact CB-CD1 3.85Å; P156-I161 HydrophobicContact CB-CG1 4.33Å; P156-I161 HydrophobicContact CG-CD1 3.78Å; P157-I161 PolarHBondContact O-N 3.24Å; D159-I161 PolarHBondContact O-N 2.94Å; I161-I164 PolarHBondContact O-N 3.36Å; I161-A165 WeakPolarHBondContact O-CB 3.26Å; I161-A165 PolarHBondContact O-N 3.35Å
162	R	94.5	Very high	90.7	Very high	34 Å²	34	58.7 Å²	58.7	13%	0.128	33%	0.334	C	S	.	.	H	α-helix	trans	-67.6	-41.4	-178	-79.7	177.8	172.6	66.4	6.5	113.4	L140 Y158 D159 A160 I164 A165 A166 L376 V378 E379	L140-R162 HydrophobicContact CD2-CG 4.06Å; Y158-R162 PolarHBondContact O-N 3.28Å; Y158-R162 PolarHBondContact OH-NE 3.44Å; Y158-R162 VanDerWaalsContact OH-NE 3.12Å; Y158-R162 PolarHBondContact OH-NH1 3.33Å; Y158-R162 PolarHBondContact OH-NH2 3.35Å; D159-R162 PolarHBondContact O-N 3.47Å; A160-R162 PolarHBondContact O-N 3.27Å; R162-I164 VanDerWaalsContact C-N 3.32Å; R162-I164 PolarHBondContact O-N 2.88Å; R162-A165 PolarHBondContact O-N 2.83Å; R162-A166 VanDerWaalsContact O-CB 3.26Å; R162-A166 WeakPolarHBondContact O-CB 3.08Å; R162-A166 PolarHBondContact O-N 3.06Å; R162-L376 WeakPolarHBondContact CD-O 3.38Å; R162-L376 PolarHBondContact NE-O 3.17Å; R162-V378 PolarHBondContact NH2-O 2.88Å; R162-E379 VanDerWaalsContact NH2-C 3.34Å; R162-E379 PolarHBondContact NH2-O 3.42Å
163	L	95.9	Very high	91.6	Very high	123 Å²	123	56.2 Å²	56.2	64%	0.644	32%	0.317	S	S	*	.	H	α-helix	trans	-65	-38.6	177.3	-70.6	172.8	0	0	0	111.4	D159 A160 A167	D159-L163 WeakPolarHBondContact O-CB 3.33Å; D159-L163 VanDerWaalsContact O-CG 3.27Å; D159-L163 WeakPolarHBondContact O-CG 3.35Å; D159-L163 PolarHBondContact O-N 3.41Å; A160-L163 PolarHBondContact O-N 2.84Å; L163-A167 VanDerWaalsContact O-CB 3.27Å; L163-A167 WeakPolarHBondContact O-CB 3.39Å; L163-A167 PolarHBondContact O-N 3.49Å
164	I	95.9	Very high	92.2	Very high	55 Å²	55	56.3 Å²	56.3	28%	0.282	31%	0.306	S	S	.	.	H	α-helix	trans	-69.2	-41.7	175.4	-68.9	166.7	0	0	0	111.1	F142 A143 L146 V147 A160 I161 R162 A167 C168	F142-I164 HydrophobicContact CD1-CG2 4.28Å; F142-I164 HydrophobicContact CE1-CG2 3.87Å; A143-I164 HydrophobicContact CB-CB 3.98Å; A143-I164 HydrophobicContact CB-CG2 3.8Å; L146-I164 HydrophobicContact CD2-CG2 4.28Å; V147-I164 HydrophobicContact CG2-CD1 3.41Å; V147-I164 VanDerWaalsContact CG2-CD1 3.41Å; A160-I164 WeakPolarHBondContact O-CB 3.37Å; A160-I164 WeakPolarHBondContact O-CD1 3.32Å; A160-I164 VanDerWaalsContact O-CG1 3.23Å; A160-I164 WeakPolarHBondContact O-CG1 3.46Å; A160-I164 PolarHBondContact O-N 3.42Å; I161-I164 PolarHBondContact O-N 3.36Å; R162-I164 VanDerWaalsContact C-N 3.32Å; R162-I164 PolarHBondContact O-N 2.88Å; I164-A167 PolarHBondContact O-N 2.83Å; I164-C168 WeakPolarHBondContact O-CB 3.26Å; I164-C168 PolarHBondContact O-N 3.35Å
165	A	96.3	Very high	92.5	Very high	0 Å²	0	53.9 Å²	53.9	0%	0	29%	0.289	C	S	.	.	H	α-helix	trans	-61	-46.3	175	0	0	0	0	0	111.4	S139 L140 A143 I161 R162 C168 I169 L376	S139-A165 WeakPolarHBondContact O-CB 3.29Å; L140-A165 HydrophobicContact CD2-CB 4.16Å; A143-A165 HydrophobicContact CB-CB 4.01Å; I161-A165 WeakPolarHBondContact O-CB 3.26Å; I161-A165 PolarHBondContact O-N 3.35Å; R162-A165 PolarHBondContact O-N 2.83Å; A165-C168 WeakPolarHBondContact O-CB 3.43Å; A165-C168 PolarHBondContact O-N 2.88Å; A165-I169 PolarHBondContact O-N 3.49Å; A165-L376 HydrophobicContact CB-CD1 4.17Å; A165-L376 HydrophobicContact CB-CD2 3.97Å
166	A	96.8	Very high	92.8	Very high	24 Å²	24	46.2 Å²	46.2	20%	0.198	25%	0.253	C	S	.	.	H	α-helix	trans	-61.8	-44.4	175.8	0	0	0	0	0	111.7	R162 C168 I169 C170 L373 L376	R162-A166 VanDerWaalsContact O-CB 3.26Å; R162-A166 WeakPolarHBondContact O-CB 3.08Å; R162-A166 PolarHBondContact O-N 3.06Å; A166-C168 VanDerWaalsContact C-N 3.29Å; A166-C168 PolarHBondContact O-N 2.87Å; A166-I169 PolarHBondContact O-N 3.24Å; A166-C170 WeakPolarHBondContact O-CB 3.23Å; A166-C170 PolarHBondContact O-N 3.38Å; A166-C170 PolarHBondContact O-SG 3.01Å; A166-L373 HydrophobicContact CB-CD2 3.67Å; A166-L376 HydrophobicContact CB-CD1 3.73Å
167	A	96.8	Very high	92.9	Very high	57 Å²	57	46 Å²	46	47%	0.471	25%	0.252	S	S	.	.	H	α-helix	trans	-60.5	-39.9	175.4	0	0	0	0	0	111.8	L163 I164 C170 M171	L163-A167 VanDerWaalsContact O-CB 3.27Å; L163-A167 WeakPolarHBondContact O-CB 3.39Å; L163-A167 PolarHBondContact O-N 3.49Å; I164-A167 PolarHBondContact O-N 2.83Å; A167-C170 PolarHBondContact O-N 3.05Å; A167-M171 WeakPolarHBondContact O-CB 3.29Å; A167-M171 PolarHBondContact O-N 3.29Å
168	C	94.9	Very high	92.6	Very high	8 Å²	8	44.6 Å²	44.6	5%	0.054	25%	0.245	C	C	.	.	H	α-helix	trans	-63.3	-47.8	176.4	-171.4	0	0	0	0	111.8	F142 I164 A165 A166 M171 L172	F142-C168 HydrophobicContact CD1-CB 3.82Å; F142-C168 HydrophobicContact CE1-CB 3.76Å; I164-C168 WeakPolarHBondContact O-CB 3.26Å; I164-C168 PolarHBondContact O-N 3.35Å; A165-C168 WeakPolarHBondContact O-CB 3.43Å; A165-C168 PolarHBondContact O-N 2.88Å; A166-C168 VanDerWaalsContact C-N 3.29Å; A166-C168 PolarHBondContact O-N 2.87Å; C168-M171 PolarHBondContact O-N 3Å; C168-L172 WeakPolarHBondContact O-CB 3.49Å; C168-L172 PolarHBondContact O-N 2.87Å
169	I	95.2	Very high	92	Very high	0 Å²	0	44.8 Å²	44.8	0%	0	25%	0.245	C	C	.	.	H	α-helix	trans	-58	-52.4	174.9	-70.9	178.1	0	0	0	110.5	A165 A166 M171 L172 I173 L327 L373 L376	A165-I169 PolarHBondContact O-N 3.49Å; A166-I169 PolarHBondContact O-N 3.24Å; I169-M171 VanDerWaalsContact C-N 3.32Å; I169-M171 PolarHBondContact O-N 3.33Å; I169-L172 PolarHBondContact O-N 3.13Å; I169-I173 HydrophobicContact CG2-CD1 3.5Å; I169-I173 HydrophobicContact CG2-CG1 4.39Å; I169-I173 VanDerWaalsContact O-CD1 3.3Å; I169-I173 WeakPolarHBondContact O-CD1 3.38Å; I169-I173 VanDerWaalsContact O-CG1 3.26Å; I169-I173 WeakPolarHBondContact O-CG1 3.24Å; I169-I173 PolarHBondContact O-N 3.36Å; I169-L327 HydrophobicContact CG1-CD2 4.04Å; I169-L373 HydrophobicContact CB-CD2 4.48Å; I169-L373 HydrophobicContact CG2-CD2 4.33Å; I169-L376 HydrophobicContact CD1-CD1 4.08Å; I169-L376 HydrophobicContact CD1-CG 4.35Å
170	C	95.8	Very high	90.9	Very high	62 Å²	62	41.8 Å²	41.8	42%	0.419	23%	0.231	S	C	.	.	H	α-helix	trans	-58.5	-42.5	179.9	-72.8	0	0	0	0	112.5	A166 A167 I173 F174	A166-C170 WeakPolarHBondContact O-CB 3.23Å; A166-C170 PolarHBondContact O-N 3.38Å; A166-C170 PolarHBondContact O-SG 3.01Å; A167-C170 PolarHBondContact O-N 3.05Å; C170-I173 PolarHBondContact O-N 2.88Å; C170-F174 WeakPolarHBondContact O-CB 3.44Å; C170-F174 PolarHBondContact O-N 3.39Å
171	M	93.1	Very high	89.8	Confident	101 Å²	101	46.4 Å²	46.4	50%	0.498	25%	0.246	S	C	.	.	H	α-helix	trans	-63.5	-45.6	177.5	-176.7	61.1	-179.9	0	0	111.3	A167 C168 I169 F174 V175	A167-M171 WeakPolarHBondContact O-CB 3.29Å; A167-M171 PolarHBondContact O-N 3.29Å; C168-M171 PolarHBondContact O-N 3Å; I169-M171 VanDerWaalsContact C-N 3.32Å; I169-M171 PolarHBondContact O-N 3.33Å; M171-F174 WeakPolarHBondContact O-CB 3.31Å; M171-F174 PolarHBondContact O-N 3.16Å; M171-V175 HydrophobicContact CE-CG2 4.01Å; M171-V175 WeakPolarHBondContact O-CG2 2.85Å; M171-V175 PolarHBondContact O-N 2.83Å; M171-V175 HydrophobicContact SD-CG2 4.47Å
172	L	91.4	Very high	88.6	Confident	1 Å²	1	53.8 Å²	53.8	1%	0.005	27%	0.273	C	S	.	.	H	α-helix	trans	-65.4	-40.1	178.5	-79.6	173.1	0	0	0	112.7	C168 I169 F174 V175 N176 Y324 L327 N328 I331	C168-L172 WeakPolarHBondContact O-CB 3.49Å; C168-L172 PolarHBondContact O-N 2.87Å; I169-L172 PolarHBondContact O-N 3.13Å; L172-F174 VanDerWaalsContact C-N 3.32Å; L172-V175 PolarHBondContact O-N 3.01Å; L172-N176 WeakPolarHBondContact O-CB 3.1Å; L172-N176 PolarHBondContact O-N 3.31Å; L172-N176 PolarHBondContact O-ND2 3.26Å; L172-Y324 HydrophobicContact CD1-CD2 4.38Å; L172-Y324 HydrophobicContact CD1-CE2 4.32Å; L172-Y324 HydrophobicContact CD2-CD1 4.13Å; L172-Y324 HydrophobicContact CD2-CD2 4.47Å; L172-Y324 HydrophobicContact CD2-CE1 3.46Å; L172-Y324 VanDerWaalsContact CD2-CE1 3.46Å; L172-Y324 HydrophobicContact CD2-CE2 3.83Å; L172-Y324 WeakPolarHBondContact CD2-OH 3.41Å; L172-Y324 HydrophobicContact CG-CD2 4.46Å; L172-Y324 HydrophobicContact CG-CE1 4.4Å; L172-Y324 HydrophobicContact CG-CE2 3.91Å; L172-L327 HydrophobicContact CD1-CB 3.76Å; L172-L327 HydrophobicContact CD1-CD2 3.53Å; L172-L327 HydrophobicContact CD1-CG 3.48Å; L172-L327 VanDerWaalsContact CD1-CG 3.48Å; L172-N328 HydrophobicContact CD1-CB 4.45Å; L172-N328 HydrophobicContact CD2-CB 3.81Å; L172-I331 HydrophobicContact CB-CD1 3.84Å; L172-I331 HydrophobicContact CD1-CD1 4.25Å
173	I	91.6	Very high	87	Confident	20 Å²	20	52.3 Å²	52.3	10%	0.103	27%	0.268	C	S	.	.	H	α-helix	trans	-60.4	-47	173.5	-65.5	153.5	0	0	0	109.8	I169 C170 V175 N176 C177 L365	I169-I173 HydrophobicContact CG2-CD1 3.5Å; I169-I173 HydrophobicContact CG2-CG1 4.39Å; I169-I173 VanDerWaalsContact O-CD1 3.3Å; I169-I173 WeakPolarHBondContact O-CD1 3.38Å; I169-I173 VanDerWaalsContact O-CG1 3.26Å; I169-I173 WeakPolarHBondContact O-CG1 3.24Å; I169-I173 PolarHBondContact O-N 3.36Å; C170-I173 PolarHBondContact O-N 2.88Å; I173-V175 PolarHBondContact O-N 3.01Å; I173-N176 PolarHBondContact O-N 3.33Å; I173-C177 WeakPolarHBondContact O-CB 3.47Å; I173-C177 PolarHBondContact O-N 2.83Å; I173-C177 PolarHBondContact O-SG 2.97Å; I173-L365 HydrophobicContact CG2-CB 4.45Å
174	F	91.6	Very high	85.5	Confident	139 Å²	139	49.1 Å²	49.1	61%	0.61	25%	0.254	S	S	*	.	H	α-helix	trans	-58	-47.9	178.6	175.8	-98.3	0	0	0	111.9	C170 M171 L172 N176 C177 A178	C170-F174 WeakPolarHBondContact O-CB 3.44Å; C170-F174 PolarHBondContact O-N 3.39Å; M171-F174 WeakPolarHBondContact O-CB 3.31Å; M171-F174 PolarHBondContact O-N 3.16Å; L172-F174 VanDerWaalsContact C-N 3.32Å; F174-N176 PolarHBondContact O-N 2.87Å; F174-C177 PolarHBondContact O-N 3.37Å; F174-A178 WeakPolarHBondContact O-CB 3.36Å; F174-A178 PolarHBondContact O-N 3.29Å
175	V	88.7	Confident	84.1	Confident	19 Å²	19	53.1 Å²	53.1	12%	0.115	27%	0.273	C	S	.	.	H	α-helix	trans	-61.3	-45.6	178.2	171.9	0	0	0	0	111.2	M171 L172 I173 C177 A178 Y179 W182	M171-V175 HydrophobicContact CE-CG2 4.01Å; M171-V175 WeakPolarHBondContact O-CG2 2.85Å; M171-V175 PolarHBondContact O-N 2.83Å; M171-V175 HydrophobicContact SD-CG2 4.47Å; L172-V175 PolarHBondContact O-N 3.01Å; I173-V175 PolarHBondContact O-N 3.01Å; V175-C177 PolarHBondContact O-N 3.4Å; V175-A178 PolarHBondContact O-N 2.85Å; V175-Y179 PolarHBondContact O-N 3.34Å; V175-W182 HydrophobicContact CG1-CB 4.33Å
176	N	86.9	Confident	82.7	Confident	0 Å²	0	55.8 Å²	55.8	0%	0	29%	0.289	C	S	.	.	H	α-helix	trans	-69.4	-31.6	-179.9	-76.3	-59.7	0	0	0	113.1	L172 I173 F174 V180 N328 L365	L172-N176 WeakPolarHBondContact O-CB 3.1Å; L172-N176 PolarHBondContact O-N 3.31Å; L172-N176 PolarHBondContact O-ND2 3.26Å; I173-N176 PolarHBondContact O-N 3.33Å; F174-N176 PolarHBondContact O-N 2.87Å; N176-V180 WeakPolarHBondContact O-CG2 3.07Å; N176-N328 PolarHBondContact ND2-OD1 3.26Å; N176-N328 PolarHBondContact OD1-OD1 2.88Å; N176-L365 HydrophobicContact CB-CD1 4Å; N176-L365 HydrophobicContact CB-CD2 4.15Å
177	C	85.9	Confident	81.2	Confident	15 Å²	15	56.4 Å²	56.4	10%	0.101	29%	0.288	C	S	.	.	H	α-helix	trans	-70.6	-33.4	171.5	-70.4	0	0	0	0	112.1	I173 F174 V175 R358 T360 V362	I173-C177 WeakPolarHBondContact O-CB 3.47Å; I173-C177 PolarHBondContact O-N 2.83Å; I173-C177 PolarHBondContact O-SG 2.97Å; F174-C177 PolarHBondContact O-N 3.37Å; V175-C177 PolarHBondContact O-N 3.4Å; C177-R358 WeakPolarHBondContact O-CD 3.32Å; C177-T360 PolarHBondContact O-OG1 3.4Å; C177-V362 HydrophobicContact CB-CG1 4.49Å; C177-V362 HydrophobicContact CB-CG2 3.99Å
178	A	84.8	Confident	79.8	Confident	25 Å²	25	58.4 Å²	58.4	21%	0.207	29%	0.291	C	S	.	.	H	α-helix	trans	-75.4	-57.7	-179.4	0	0	0	0	0	112.7	F174 V175 R358	F174-A178 WeakPolarHBondContact O-CB 3.36Å; F174-A178 PolarHBondContact O-N 3.29Å; V175-A178 PolarHBondContact O-N 2.85Å; A178-R358 WeakPolarHBondContact O-CD 3.29Å
179	Y	77.9	Confident	78.7	Confident	100 Å²	100	63.8 Å²	63.8	39%	0.392	32%	0.318	S	S	.	.			trans	-158.7	108.5	179.4	-165.7	-116.6	0	0	0	111.6	V175 K181 W182	V175-Y179 PolarHBondContact O-N 3.34Å; Y179-K181 HydrophobicContact CD1-CB 3.89Å; Y179-K181 HydrophobicContact CD1-CG 4.44Å; Y179-K181 HydrophobicContact CE1-CB 3.48Å; Y179-K181 VanDerWaalsContact CE1-CB 3.48Å; Y179-K181 HydrophobicContact CE1-CD 4.01Å; Y179-K181 HydrophobicContact CE1-CG 3.83Å; Y179-K181 PolarHBondContact O-N 3.2Å; Y179-K181 VanDerWaalsContact O-N 3.14Å; Y179-K181 WeakPolarHBondContact OH-CD 3.37Å; Y179-W182 AromaticContact CD1-CD1 3.42Å; Y179-W182 VanDerWaalsContact CD1-CD1 3.42Å; Y179-W182 HydrophobicContact CD1-CD2 4.5Å; Y179-W182 AromaticContact CD1-CG 3.91Å; Y179-W182 HydrophobicContact CD1-CG 3.91Å; Y179-W182 AromaticContact CD1-NE1 3.68Å; Y179-W182 AromaticContact CE1-CD1 4Å; Y179-W182 PolarHBondContact O-N 3.4Å; Y179-W182 VanDerWaalsContact O-N 3.07Å
180	V	67.8	Low	77.7	Confident	50 Å²	50	65.4 Å²	65.4	30%	0.303	33%	0.325	S	S	.	.	H	α-helix	trans	-58.1	-32.6	-174.8	171.8	0	0	0	0	112.8	N176 W182 G183 T184 T360	N176-V180 WeakPolarHBondContact O-CG2 3.07Å; V180-W182 VanDerWaalsContact C-N 3.27Å; V180-W182 PolarHBondContact O-N 3.29Å; V180-G183 PolarHBondContact O-N 3.02Å; V180-G183 VanDerWaalsContact O-N 3.12Å; V180-T184 PolarHBondContact O-N 3.48Å; V180-T360 HydrophobicContact CG2-CG2 3.51Å
181	K	70.1	Confident	76.5	Confident	129 Å²	129	63.1 Å²	63.1	56%	0.561	31%	0.31	S	S	*	.	H	α-helix	trans	-68.8	-23.4	-179.1	-49.8	-170.3	-174	169.3	0	113.6	Y179 G183 T184 M185	Y179-K181 HydrophobicContact CD1-CB 3.89Å; Y179-K181 HydrophobicContact CD1-CG 4.44Å; Y179-K181 HydrophobicContact CE1-CB 3.48Å; Y179-K181 VanDerWaalsContact CE1-CB 3.48Å; Y179-K181 HydrophobicContact CE1-CD 4.01Å; Y179-K181 HydrophobicContact CE1-CG 3.83Å; Y179-K181 PolarHBondContact O-N 3.2Å; Y179-K181 VanDerWaalsContact O-N 3.14Å; Y179-K181 WeakPolarHBondContact OH-CD 3.37Å; K181-G183 VanDerWaalsContact C-N 3.34Å; K181-T184 WeakPolarHBondContact CA-OG1 3.33Å; K181-T184 PolarHBondContact O-OG1 3.41Å; K181-M185 WeakPolarHBondContact O-CG 3.49Å; K181-M185 PolarHBondContact O-N 2.6Å; K181-M185 VanDerWaalsContact O-N 3.15Å
182	W	68.5	Low	75.6	Confident	167 Å²	167	65.8 Å²	65.8	63%	0.633	32%	0.315	S	S	*	.	H	α-helix	trans	-68.3	-39.4	172.7	-72.9	2.4	0	0	0	110.7	V175 Y179 V180 T184 V186	V175-W182 HydrophobicContact CG1-CB 4.33Å; Y179-W182 AromaticContact CD1-CD1 3.42Å; Y179-W182 VanDerWaalsContact CD1-CD1 3.42Å; Y179-W182 HydrophobicContact CD1-CD2 4.5Å; Y179-W182 AromaticContact CD1-CG 3.91Å; Y179-W182 HydrophobicContact CD1-CG 3.91Å; Y179-W182 AromaticContact CD1-NE1 3.68Å; Y179-W182 AromaticContact CE1-CD1 4Å; Y179-W182 PolarHBondContact O-N 3.4Å; Y179-W182 VanDerWaalsContact O-N 3.07Å; V180-W182 VanDerWaalsContact C-N 3.27Å; V180-W182 PolarHBondContact O-N 3.29Å; W182-T184 PolarHBondContact O-N 2.83Å; W182-V186 VanDerWaalsContact O-CG2 3.29Å; W182-V186 WeakPolarHBondContact O-CG2 3.35Å; W182-V186 PolarHBondContact O-N 3.4Å
183	G	61.2	Low	74.8	Confident	3 Å²	3	66.9 Å²	66.9	3%	0.031	33%	0.325	C	S	.	.	H	α-helix	trans	-59.9	-44.6	174.7	0	0	0	0	0	112.2	V180 K181 Q187 N328	V180-G183 PolarHBondContact O-N 3.02Å; V180-G183 VanDerWaalsContact O-N 3.12Å; K181-G183 VanDerWaalsContact C-N 3.34Å; G183-Q187 WeakPolarHBondContact O-CB 3.42Å; G183-Q187 PolarHBondContact O-N 3.42Å; G183-Q187 VanDerWaalsContact O-N 3.12Å; G183-N328 PolarHBondContact O-ND2 3.07Å
184	T	64.3	Low	74.1	Confident	57 Å²	57	66.2 Å²	66.2	35%	0.35	32%	0.321	S	S	.	.	H	α-helix	trans	-69.1	-41.1	-178.7	58.9	0	0	0	0	113	V180 K181 W182 V186 Q187 D188	V180-T184 PolarHBondContact O-N 3.48Å; K181-T184 WeakPolarHBondContact CA-OG1 3.33Å; K181-T184 PolarHBondContact O-OG1 3.41Å; W182-T184 PolarHBondContact O-N 2.83Å; T184-V186 VanDerWaalsContact C-N 3.35Å; T184-V186 PolarHBondContact O-N 3.21Å; T184-Q187 PolarHBondContact O-N 3.45Å; T184-D188 PolarHBondContact O-N 3.06Å; T184-D188 VanDerWaalsContact O-N 3.17Å
185	M	67.2	Low	73.6	Confident	138 Å²	138	61.9 Å²	61.9	68%	0.68	30%	0.304	S	S	*	.	H	α-helix	trans	-64.2	-39.3	178.1	-73.1	-176.1	71.5	0	0	112.7	K181 Q187	K181-M185 WeakPolarHBondContact O-CG 3.49Å; K181-M185 PolarHBondContact O-N 2.6Å; K181-M185 VanDerWaalsContact O-N 3.15Å; M185-Q187 VanDerWaalsContact C-N 3.35Å
186	V	66.8	Low	73.3	Confident	57 Å²	57	67 Å²	67	35%	0.345	33%	0.328	S	S	.	.	H	α-helix	trans	-68.4	-37.4	178.5	170.7	0	0	0	0	110.9	W182 T184 F190 Y324	W182-V186 VanDerWaalsContact O-CG2 3.29Å; W182-V186 WeakPolarHBondContact O-CG2 3.35Å; W182-V186 PolarHBondContact O-N 3.4Å; T184-V186 VanDerWaalsContact C-N 3.35Å; T184-V186 PolarHBondContact O-N 3.21Å; V186-F190 HydrophobicContact CG1-CD2 3.76Å; V186-F190 HydrophobicContact CG1-CE1 4.47Å; V186-F190 HydrophobicContact CG1-CE2 3.11Å; V186-F190 HydrophobicContact CG1-CZ 3.54Å; V186-F190 VanDerWaalsContact O-CD2 3.31Å; V186-F190 WeakPolarHBondContact O-CD2 3.32Å; V186-F190 VanDerWaalsContact O-CG 3.29Å; V186-F190 WeakPolarHBondContact O-CG 3.45Å; V186-F190 PolarHBondContact O-N 2.96Å; V186-Y324 HydrophobicContact CG1-CD1 4.37Å; V186-Y324 HydrophobicContact CG1-CE1 3.92Å
187	Q	66	Low	73.1	Confident	36 Å²	36	67.1 Å²	67.1	17%	0.168	33%	0.329	C	S	.	.	H	α-helix	trans	-64.2	-41	177.3	-179.8	178.7	-31.9	0	0	113.3	G183 T184 M185 L189 F190 T191 N328	G183-Q187 WeakPolarHBondContact O-CB 3.42Å; G183-Q187 PolarHBondContact O-N 3.42Å; G183-Q187 VanDerWaalsContact O-N 3.12Å; T184-Q187 PolarHBondContact O-N 3.45Å; M185-Q187 VanDerWaalsContact C-N 3.35Å; Q187-L189 PolarHBondContact O-N 3.49Å; Q187-F190 PolarHBondContact O-N 3.43Å; Q187-T191 PolarHBondContact O-N 2.72Å; Q187-T191 VanDerWaalsContact O-N 3.07Å; Q187-T191 PolarHBondContact O-OG1 3.36Å; Q187-N328 PolarHBondContact OE1-ND2 3.45Å
188	D	66.5	Low	73.2	Confident	100 Å²	100	66.6 Å²	66.6	54%	0.535	33%	0.325	S	S	.	.	H	α-helix	trans	-61.6	-44.8	-179.9	-73.7	-16.8	0	0	0	111.4	T184 F190 T191 Y192	T184-D188 PolarHBondContact O-N 3.06Å; T184-D188 VanDerWaalsContact O-N 3.17Å; D188-F190 VanDerWaalsContact C-N 3.33Å; D188-F190 PolarHBondContact O-N 3.47Å; D188-T191 PolarHBondContact O-N 2.96Å; D188-Y192 WeakPolarHBondContact O-CD2 3.34Å
189	L	71.1	Confident	73.5	Confident	120 Å²	120	69.4 Å²	69.4	63%	0.628	34%	0.336	S	S	*	.	H	α-helix	trans	-59.7	-42.9	176.5	-179	63.3	0	0	0	112	Q187 T191 Y192 A193	Q187-L189 PolarHBondContact O-N 3.49Å; L189-T191 VanDerWaalsContact C-N 3.28Å; L189-T191 PolarHBondContact O-N 3.08Å; L189-Y192 PolarHBondContact O-N 3.34Å; L189-A193 PolarHBondContact O-N 3.48Å
190	F	73.9	Confident	74.1	Confident	34 Å²	34	67.2 Å²	67.2	15%	0.149	33%	0.331	C	S	.	.	H	α-helix	trans	-71.2	-23.9	-178.2	-63.5	-20.6	0	0	0	113.5	V186 Q187 D188 A193 K194 M321 Y324	V186-F190 HydrophobicContact CG1-CD2 3.76Å; V186-F190 HydrophobicContact CG1-CE1 4.47Å; V186-F190 HydrophobicContact CG1-CE2 3.11Å; V186-F190 HydrophobicContact CG1-CZ 3.54Å; V186-F190 VanDerWaalsContact O-CD2 3.31Å; V186-F190 WeakPolarHBondContact O-CD2 3.32Å; V186-F190 VanDerWaalsContact O-CG 3.29Å; V186-F190 WeakPolarHBondContact O-CG 3.45Å; V186-F190 PolarHBondContact O-N 2.96Å; Q187-F190 PolarHBondContact O-N 3.43Å; D188-F190 VanDerWaalsContact C-N 3.33Å; D188-F190 PolarHBondContact O-N 3.47Å; F190-A193 PolarHBondContact O-N 2.84Å; F190-K194 PolarHBondContact O-N 2.86Å; F190-K194 VanDerWaalsContact O-N 3.09Å; F190-M321 HydrophobicContact CB-CB 4.3Å; F190-M321 HydrophobicContact CD1-CB 3.78Å; F190-M321 HydrophobicContact CD1-CG 3.87Å; F190-M321 HydrophobicContact CD1-SD 3.78Å; F190-M321 HydrophobicContact CD2-CB 4.47Å; F190-M321 HydrophobicContact CE1-CB 4.18Å; F190-M321 HydrophobicContact CE1-CG 3.78Å; F190-M321 HydrophobicContact CE1-SD 3.67Å; F190-M321 HydrophobicContact CG-CB 3.94Å; F190-M321 HydrophobicContact CG-CG 4.46Å; F190-M321 HydrophobicContact CZ-CG 4.28Å; F190-Y324 AromaticContact CD2-CD1 3.92Å; F190-Y324 HydrophobicContact CD2-CD1 3.92Å; F190-Y324 AromaticContact CE2-CD1 3.45Å; F190-Y324 HydrophobicContact CE2-CD1 3.45Å; F190-Y324 VanDerWaalsContact CE2-CD1 3.45Å; F190-Y324 AromaticContact CE2-CE1 3.98Å; F190-Y324 HydrophobicContact CE2-CE1 3.98Å; F190-Y324 HydrophobicContact CE2-CG 4.16Å
191	T	70.9	Confident	75.2	Confident	15 Å²	15	64.8 Å²	64.8	9%	0.092	32%	0.316	C	S	.	.	H	α-helix	trans	-67.1	-38.5	175.3	-58.2	0	0	0	0	111.8	Q187 D188 L189 K194 L195	Q187-T191 PolarHBondContact O-N 2.72Å; Q187-T191 VanDerWaalsContact O-N 3.07Å; Q187-T191 PolarHBondContact O-OG1 3.36Å; D188-T191 PolarHBondContact O-N 2.96Å; L189-T191 VanDerWaalsContact C-N 3.28Å; L189-T191 PolarHBondContact O-N 3.08Å; T191-K194 VanDerWaalsContact O-CG 3.27Å; T191-K194 WeakPolarHBondContact O-CG 3.33Å; T191-L195 WeakPolarHBondContact O-CG 3.31Å; T191-L195 PolarHBondContact O-N 2.85Å
192	Y	74.6	Confident	76.3	Confident	156 Å²	156	59.7 Å²	59.7	61%	0.612	30%	0.295	S	S	*	.	H	α-helix	trans	-68.9	-42.4	173.6	-66	-75.1	0	0	0	112	D188 L189 K194 L195 M196	D188-Y192 WeakPolarHBondContact O-CD2 3.34Å; L189-Y192 PolarHBondContact O-N 3.34Å; Y192-K194 VanDerWaalsContact C-N 3.34Å; Y192-K194 PolarHBondContact O-N 3.48Å; Y192-L195 PolarHBondContact O-N 3.17Å; Y192-M196 WeakPolarHBondContact O-CG 3.35Å; Y192-M196 PolarHBondContact O-N 3.07Å
193	A	75.2	Confident	77.6	Confident	25 Å²	25	55.9 Å²	55.9	21%	0.207	29%	0.286	C	S	.	.	H	α-helix	trans	-61.4	-40.4	-178.5	0	0	0	0	0	112.7	L189 F190 M196 S197 M321	L189-A193 PolarHBondContact O-N 3.48Å; F190-A193 PolarHBondContact O-N 2.84Å; A193-M196 PolarHBondContact O-N 3.06Å; A193-S197 PolarHBondContact O-N 3.02Å; A193-M321 HydrophobicContact CB-CE 3.68Å
194	K	76.7	Confident	79	Confident	6 Å²	6	56.7 Å²	56.7	3%	0.026	29%	0.289	C	S	.	.	H	α-helix	trans	-70.4	-37.1	178.5	72.2	-178.9	177.8	-166.3	0	113.3	G51 I54 F190 T191 Y192 M196 S197 L198 S322	G51-K194 PolarHBondContact O-NZ 3.43Å; I54-K194 HydrophobicContact CG2-CD 4.47Å; I54-K194 VanDerWaalsContact O-CD 3.23Å; I54-K194 WeakPolarHBondContact O-CD 3.21Å; I54-K194 WeakPolarHBondContact O-CE 3.36Å; I54-K194 PolarHBondContact O-NZ 2.98Å; F190-K194 PolarHBondContact O-N 2.86Å; F190-K194 VanDerWaalsContact O-N 3.09Å; T191-K194 VanDerWaalsContact O-CG 3.27Å; T191-K194 WeakPolarHBondContact O-CG 3.33Å; Y192-K194 VanDerWaalsContact C-N 3.34Å; Y192-K194 PolarHBondContact O-N 3.48Å; K194-M196 VanDerWaalsContact C-N 3.3Å; K194-M196 PolarHBondContact O-N 3.26Å; K194-S197 PolarHBondContact O-N 3.04Å; K194-S197 VanDerWaalsContact O-N 3.14Å; K194-S197 PolarHBondContact O-OG 2.7Å; K194-L198 PolarHBondContact O-N 3.42Å; K194-L198 VanDerWaalsContact O-N 3.13Å; K194-S322 WeakPolarHBondContact CD-OG 3.47Å
195	L	81.1	Confident	80.4	Confident	48 Å²	48	54 Å²	54	25%	0.251	27%	0.273	S	S	.	.	H	α-helix	trans	-62.7	-41.1	176.8	-71.7	176.1	0	0	0	110.7	V50 I54 T191 Y192 S197 L198 I199	V50-L195 HydrophobicContact CG1-CD2 4.24Å; I54-L195 HydrophobicContact CD1-CD2 3.91Å; T191-L195 WeakPolarHBondContact O-CG 3.31Å; T191-L195 PolarHBondContact O-N 2.85Å; Y192-L195 PolarHBondContact O-N 3.17Å; L195-S197 VanDerWaalsContact C-N 3.31Å; L195-S197 PolarHBondContact O-N 3.19Å; L195-L198 PolarHBondContact O-N 3.5Å; L195-I199 WeakPolarHBondContact O-CD1 3.48Å; L195-I199 VanDerWaalsContact O-CG1 3.26Å; L195-I199 WeakPolarHBondContact O-CG1 3.44Å; L195-I199 PolarHBondContact O-N 3.37Å
196	M	82.5	Confident	81.6	Confident	126 Å²	126	52 Å²	52	62%	0.621	26%	0.264	S	S	*	.	H	α-helix	trans	-60.2	-39.9	174.1	-70.4	-58.6	-62	0	0	112.5	Y192 A193 K194 I199 L200	Y192-M196 WeakPolarHBondContact O-CG 3.35Å; Y192-M196 PolarHBondContact O-N 3.07Å; A193-M196 PolarHBondContact O-N 3.06Å; K194-M196 VanDerWaalsContact C-N 3.3Å; K194-M196 PolarHBondContact O-N 3.26Å; M196-I199 PolarHBondContact O-N 3.38Å; M196-L200 WeakPolarHBondContact O-CB 3.37Å; M196-L200 PolarHBondContact O-N 3.39Å
197	S	82.7	Confident	82.9	Confident	3 Å²	3	54.4 Å²	54.4	2%	0.021	27%	0.273	C	S	.	.	H	α-helix	trans	-65.7	-38.6	178.7	74.1	0	0	0	0	113.3	A193 K194 L195 L200 I201	A193-S197 PolarHBondContact O-N 3.02Å; K194-S197 PolarHBondContact O-N 3.04Å; K194-S197 VanDerWaalsContact O-N 3.14Å; K194-S197 PolarHBondContact O-OG 2.7Å; L195-S197 VanDerWaalsContact C-N 3.31Å; L195-S197 PolarHBondContact O-N 3.19Å; S197-L200 WeakPolarHBondContact O-CB 3.08Å; S197-L200 PolarHBondContact O-N 3.43Å; S197-I201 WeakPolarHBondContact O-CG1 3.19Å; S197-I201 PolarHBondContact O-N 2.87Å; S197-I201 VanDerWaalsContact O-N 3.13Å
198	L	88.4	Confident	84.1	Confident	3 Å²	3	54.4 Å²	54.4	2%	0.016	27%	0.272	C	S	.	.	H	α-helix	trans	-71.4	-40.9	176.5	-70	173.1	0	0	0	111.7	I54 I58 F59 K194 L195 L200 I201 I202 I276 T280	I54-L198 HydrophobicContact CD1-CD1 4.48Å; I54-L198 HydrophobicContact CG2-CD1 3.2Å; I58-L198 HydrophobicContact CG1-CD2 4.46Å; I58-L198 HydrophobicContact CG2-CD2 4.17Å; F59-L198 HydrophobicContact CE1-CD2 3.96Å; F59-L198 HydrophobicContact CZ-CD2 3.94Å; F59-L198 HydrophobicContact CZ-CG 4.37Å; K194-L198 PolarHBondContact O-N 3.42Å; K194-L198 VanDerWaalsContact O-N 3.13Å; L195-L198 PolarHBondContact O-N 3.5Å; L198-L200 VanDerWaalsContact C-N 3.26Å; L198-L200 PolarHBondContact O-N 3.46Å; L198-I201 HydrophobicContact CD2-CD1 4.42Å; L198-I201 PolarHBondContact O-N 3.21Å; L198-I202 VanDerWaalsContact O-CG1 3.28Å; L198-I202 WeakPolarHBondContact O-CG1 3.48Å; L198-I202 PolarHBondContact O-N 3.46Å; L198-I276 HydrophobicContact CB-CG2 4.38Å; L198-I276 HydrophobicContact CD1-CG2 3.97Å; L198-T280 HydrophobicContact CD2-CG2 4.01Å
199	I	90.1	Very high	85.4	Confident	85 Å²	85	53 Å²	53	44%	0.436	26%	0.264	S	S	.	.	H	α-helix	trans	-58.4	-42.5	174	-69.3	166	0	0	0	110.2	L195 M196 I202 I203	L195-I199 WeakPolarHBondContact O-CD1 3.48Å; L195-I199 VanDerWaalsContact O-CG1 3.26Å; L195-I199 WeakPolarHBondContact O-CG1 3.44Å; L195-I199 PolarHBondContact O-N 3.37Å; M196-I199 PolarHBondContact O-N 3.38Å; I199-I202 PolarHBondContact O-N 2.91Å; I199-I203 HydrophobicContact CG2-CD1 3.61Å; I199-I203 HydrophobicContact CG2-CG1 4.24Å; I199-I203 WeakPolarHBondContact O-CB 3.3Å; I199-I203 VanDerWaalsContact O-CG1 3.26Å; I199-I203 WeakPolarHBondContact O-CG1 3.44Å; I199-I203 PolarHBondContact O-N 3.1Å
200	L	89.8	Confident	86.4	Confident	53 Å²	53	51.5 Å²	51.5	28%	0.277	27%	0.269	S	S	.	.	H	α-helix	trans	-59.4	-47.2	175.9	-179.5	64.8	0	0	0	112	M196 S197 L198 I202 I203 I204 L308 I314 I315	M196-L200 WeakPolarHBondContact O-CB 3.37Å; M196-L200 PolarHBondContact O-N 3.39Å; S197-L200 WeakPolarHBondContact O-CB 3.08Å; S197-L200 PolarHBondContact O-N 3.43Å; L198-L200 VanDerWaalsContact C-N 3.26Å; L198-L200 PolarHBondContact O-N 3.46Å; L200-I202 VanDerWaalsContact C-N 3.34Å; L200-I202 PolarHBondContact O-N 2.67Å; L200-I203 PolarHBondContact O-N 3.48Å; L200-I204 HydrophobicContact CD1-CD1 3.87Å; L200-I204 HydrophobicContact CD1-CG1 4.41Å; L200-I204 HydrophobicContact CG-CD1 3.9Å; L200-I204 WeakPolarHBondContact O-CD1 3.4Å; L200-I204 VanDerWaalsContact O-CG1 3.25Å; L200-I204 WeakPolarHBondContact O-CG1 3.45Å; L200-I204 PolarHBondContact O-N 3.3Å; L200-I204 VanDerWaalsContact O-N 3.1Å; L200-L308 HydrophobicContact CD2-CD1 4.27Å; L200-L308 HydrophobicContact CD2-CD2 4.34Å; L200-I314 HydrophobicContact CD2-CG2 4.47Å; L200-I315 HydrophobicContact CD2-CD1 4.21Å
201	I	91.5	Very high	87.2	Confident	0 Å²	0	57.1 Å²	57.1	0%	0	29%	0.293	C	S	.	.	H	α-helix	trans	-59.3	-46.2	177.3	-68.4	163.3	0	0	0	110.6	F59 S197 L198 I204 G205 T280 A283 Y284 A300 F303 I315	F59-I201 HydrophobicContact CE1-CD1 4.48Å; S197-I201 WeakPolarHBondContact O-CG1 3.19Å; S197-I201 PolarHBondContact O-N 2.87Å; S197-I201 VanDerWaalsContact O-N 3.13Å; L198-I201 HydrophobicContact CD2-CD1 4.42Å; L198-I201 PolarHBondContact O-N 3.21Å; I201-I204 PolarHBondContact O-N 2.92Å; I201-G205 PolarHBondContact O-N 2.95Å; I201-T280 HydrophobicContact CG2-CG2 4.09Å; I201-A283 HydrophobicContact CG2-CB 3.73Å; I201-A283 WeakPolarHBondContact O-CB 3.25Å; I201-Y284 HydrophobicContact CD1-CE1 4.2Å; I201-Y284 HydrophobicContact CG2-CD1 4.27Å; I201-Y284 HydrophobicContact CG2-CE1 3.85Å; I201-A300 HydrophobicContact CD1-CB 4.34Å; I201-F303 HydrophobicContact CB-CE1 4.18Å; I201-F303 HydrophobicContact CB-CZ 4.48Å; I201-F303 HydrophobicContact CG1-CD1 4.1Å; I201-F303 HydrophobicContact CG1-CE1 3.91Å; I201-F303 HydrophobicContact CG2-CD1 4.46Å; I201-F303 HydrophobicContact CG2-CE1 4.04Å; I201-F303 HydrophobicContact CG2-CE2 4.4Å; I201-F303 HydrophobicContact CG2-CZ 4Å; I201-I315 HydrophobicContact CD1-CD1 4.45Å; I201-I315 HydrophobicContact CG1-CD1 4.23Å
202	I	94.3	Very high	88	Confident	21 Å²	21	58.8 Å²	58.8	11%	0.108	31%	0.314	C	S	.	.	H	α-helix	trans	-63.3	-47.4	-179.5	-67.8	168.3	0	0	0	111.3	L198 I199 L200 I204 G205 I206 I276 L279	L198-I202 VanDerWaalsContact O-CG1 3.28Å; L198-I202 WeakPolarHBondContact O-CG1 3.48Å; L198-I202 PolarHBondContact O-N 3.46Å; I199-I202 PolarHBondContact O-N 2.91Å; L200-I202 VanDerWaalsContact C-N 3.34Å; L200-I202 PolarHBondContact O-N 2.67Å; I202-I204 VanDerWaalsContact C-N 3.3Å; I202-I204 PolarHBondContact O-N 3.4Å; I202-G205 PolarHBondContact O-N 3.47Å; I202-I206 HydrophobicContact CG2-CD1 3.86Å; I202-I206 HydrophobicContact CG2-CG1 4.47Å; I202-I206 WeakPolarHBondContact O-CG1 3.04Å; I202-I206 PolarHBondContact O-N 3.43Å; I202-I276 HydrophobicContact CD1-CG2 4.25Å; I202-L279 HydrophobicContact CD1-CB 3.92Å; I202-L279 HydrophobicContact CD1-CD1 4.46Å; I202-L279 HydrophobicContact CG1-CB 3.84Å; I202-L279 HydrophobicContact CG2-CB 4.04Å; I202-L279 HydrophobicContact CG2-CD1 4.06Å
203	I	94	Very high	88.7	Confident	88 Å²	88	54.9 Å²	54.9	45%	0.451	30%	0.301	S	S	.	.	H	α-helix	trans	-58.5	-45.5	179.3	-71.4	169.4	0	0	0	110.4	I199 L200 G205 I206 M207	I199-I203 HydrophobicContact CG2-CD1 3.61Å; I199-I203 HydrophobicContact CG2-CG1 4.24Å; I199-I203 WeakPolarHBondContact O-CB 3.3Å; I199-I203 VanDerWaalsContact O-CG1 3.26Å; I199-I203 WeakPolarHBondContact O-CG1 3.44Å; I199-I203 PolarHBondContact O-N 3.1Å; L200-I203 PolarHBondContact O-N 3.48Å; I203-G205 VanDerWaalsContact C-N 3.35Å; I203-G205 PolarHBondContact O-N 3.4Å; I203-I206 PolarHBondContact O-N 3Å; I203-M207 HydrophobicContact CG2-CG 4.48Å; I203-M207 HydrophobicContact CG2-SD 4.14Å; I203-M207 WeakPolarHBondContact O-CG 3.29Å; I203-M207 PolarHBondContact O-N 3.34Å
204	I	91.6	Very high	89.3	Confident	19 Å²	19	56.4 Å²	56.4	10%	0.097	31%	0.308	C	S	.	.	H	α-helix	trans	-64	-41.7	179	-68.9	167.2	0	0	0	111.2	L200 I201 I202 M207 K208 F303 V307 L308	L200-I204 HydrophobicContact CD1-CD1 3.87Å; L200-I204 HydrophobicContact CD1-CG1 4.41Å; L200-I204 HydrophobicContact CG-CD1 3.9Å; L200-I204 WeakPolarHBondContact O-CD1 3.4Å; L200-I204 VanDerWaalsContact O-CG1 3.25Å; L200-I204 WeakPolarHBondContact O-CG1 3.45Å; L200-I204 PolarHBondContact O-N 3.3Å; L200-I204 VanDerWaalsContact O-N 3.1Å; I201-I204 PolarHBondContact O-N 2.92Å; I202-I204 VanDerWaalsContact C-N 3.3Å; I202-I204 PolarHBondContact O-N 3.4Å; I204-M207 PolarHBondContact O-N 3.06Å; I204-K208 PolarHBondContact O-N 3.32Å; I204-F303 HydrophobicContact CB-CE1 4.39Å; I204-F303 HydrophobicContact CB-CZ 3.93Å; I204-F303 HydrophobicContact CD1-CE1 4.26Å; I204-F303 HydrophobicContact CG2-CE1 4.18Å; I204-F303 HydrophobicContact CG2-CE2 4.47Å; I204-F303 HydrophobicContact CG2-CZ 3.59Å; I204-V307 HydrophobicContact CG2-CB 4.05Å; I204-V307 HydrophobicContact CG2-CG1 3.34Å; I204-V307 HydrophobicContact CG2-CG2 4.45Å; I204-L308 HydrophobicContact CD1-CD2 3.35Å; I204-L308 HydrophobicContact CD1-CG 4.08Å
205	G	92.6	Very high	89.8	Confident	2 Å²	2	63 Å²	63	2%	0.021	34%	0.339	C	S	.	.	H	α-helix	trans	-57.1	-48.7	173.8	0	0	0	0	0	112.1	I201 I202 I203 M207 K208 I209	I201-G205 PolarHBondContact O-N 2.95Å; I202-G205 PolarHBondContact O-N 3.47Å; I203-G205 VanDerWaalsContact C-N 3.35Å; I203-G205 PolarHBondContact O-N 3.4Å; G205-M207 VanDerWaalsContact C-N 3.33Å; G205-M207 PolarHBondContact O-N 2.9Å; G205-K208 PolarHBondContact O-N 2.97Å; G205-I209 WeakPolarHBondContact O-CG1 3.49Å; G205-I209 PolarHBondContact O-N 3.25Å
206	I	94	Very high	89.9	Confident	95 Å²	95	63.1 Å²	63.1	49%	0.487	34%	0.34	S	S	.	.	H	α-helix	trans	-60.4	-42.9	177	-66.4	168	0	0	0	110.9	I202 I203 K208 I209 A210	I202-I206 HydrophobicContact CG2-CD1 3.86Å; I202-I206 HydrophobicContact CG2-CG1 4.47Å; I202-I206 WeakPolarHBondContact O-CG1 3.04Å; I202-I206 PolarHBondContact O-N 3.43Å; I203-I206 PolarHBondContact O-N 3Å; I206-K208 PolarHBondContact O-N 3.46Å; I206-I209 PolarHBondContact O-N 3.39Å; I206-A210 WeakPolarHBondContact O-CB 3.33Å; I206-A210 PolarHBondContact O-N 3.27Å
207	M	93.1	Very high	90.1	Very high	108 Å²	108	59.7 Å²	59.7	53%	0.532	32%	0.322	S	S	.	.	H	α-helix	trans	-62.3	-40	177.5	-72.5	179.2	69.8	0	0	112.7	I203 I204 G205 A210 K211	I203-M207 HydrophobicContact CG2-CG 4.48Å; I203-M207 HydrophobicContact CG2-SD 4.14Å; I203-M207 WeakPolarHBondContact O-CG 3.29Å; I203-M207 PolarHBondContact O-N 3.34Å; I204-M207 PolarHBondContact O-N 3.06Å; G205-M207 VanDerWaalsContact C-N 3.33Å; G205-M207 PolarHBondContact O-N 2.9Å; M207-A210 PolarHBondContact O-N 3.29Å; M207-K211 WeakPolarHBondContact O-CG 3.45Å; M207-K211 PolarHBondContact O-N 2.94Å; M207-K211 VanDerWaalsContact O-N 3.14Å
208	K	91.7	Very high	90.3	Very high	35 Å²	35	66.6 Å²	66.6	15%	0.152	35%	0.353	C	S	.	.	H	α-helix	trans	-67.3	-40.5	175.8	-81.1	-179.2	158.3	-89.5	0	112.1	I204 G205 I206 A210 K211 G212 E213 V286 A287 V307	I204-K208 PolarHBondContact O-N 3.32Å; G205-K208 PolarHBondContact O-N 2.97Å; I206-K208 PolarHBondContact O-N 3.46Å; K208-A210 VanDerWaalsContact C-N 3.32Å; K208-A210 PolarHBondContact O-N 2.94Å; K208-K211 PolarHBondContact O-N 3.29Å; K208-G212 PolarHBondContact O-N 2.9Å; K208-E213 HydrophobicContact CB-CB 4.42Å; K208-E213 IonicContact NZ-OE2 2.67Å; K208-E213 PolarHBondContact NZ-OE2 3.44Å; K208-E213 PolarHBondContact O-N 3.06Å; K208-E213 VanDerWaalsContact O-N 3.14Å; K208-V286 HydrophobicContact CB-CG1 3.42Å; K208-V286 VanDerWaalsContact CB-CG1 3.42Å; K208-V286 HydrophobicContact CD-CG1 4.16Å; K208-V286 HydrophobicContact CG-CG1 4.43Å; K208-A287 HydrophobicContact CD-CB 3.97Å; K208-V307 HydrophobicContact CD-CG1 4.45Å; K208-V307 HydrophobicContact CD-CG2 4.4Å; K208-V307 VanDerWaalsContact CE-CG2 3.43Å
209	I	92.9	Very high	90.3	Very high	72 Å²	72	71.6 Å²	71.6	37%	0.369	38%	0.38	S	S	.	.	H	α-helix	trans	-60	-45.1	172.9	-65.6	169.4	0	0	0	110.4	G205 I206 K211 G212 T214 V282 V286	G205-I209 WeakPolarHBondContact O-CG1 3.49Å; G205-I209 PolarHBondContact O-N 3.25Å; I206-I209 PolarHBondContact O-N 3.39Å; I209-K211 PolarHBondContact O-N 3.4Å; I209-G212 PolarHBondContact O-N 2.93Å; I209-T214 HydrophobicContact CG1-CG2 4.45Å; I209-T214 HydrophobicContact CG2-CG2 4.17Å; I209-V282 HydrophobicContact CD1-CG1 3.83Å; I209-V286 HydrophobicContact CD1-CG2 3.91Å; I209-V286 HydrophobicContact CG1-CG1 4.18Å; I209-V286 HydrophobicContact CG1-CG2 3.58Å
210	A	92.4	Very high	90.3	Very high	87 Å²	87	69.2 Å²	69.2	72%	0.719	37%	0.37	S	S	*	.	H	α-helix	trans	-62.9	-25.7	178.8	0	0	0	0	0	113.3	I206 M207 K208 G212	I206-A210 WeakPolarHBondContact O-CB 3.33Å; I206-A210 PolarHBondContact O-N 3.27Å; M207-A210 PolarHBondContact O-N 3.29Å; K208-A210 VanDerWaalsContact C-N 3.32Å; K208-A210 PolarHBondContact O-N 2.94Å; A210-G212 VanDerWaalsContact C-N 3.3Å
211	K	92.1	Very high	90.5	Very high	152 Å²	152	72.4 Å²	72.4	66%	0.661	38%	0.382	S	S	*	.	T	Hydrogen-bonded Turn	trans	-81	-5	172.4	-72	177.5	179.9	-177.2	0	114	M207 K208 I209 E213	M207-K211 WeakPolarHBondContact O-CG 3.45Å; M207-K211 PolarHBondContact O-N 2.94Å; M207-K211 VanDerWaalsContact O-N 3.14Å; K208-K211 PolarHBondContact O-N 3.29Å; I209-K211 PolarHBondContact O-N 3.4Å; K211-E213 HydrophobicContact CB-CG 4.43Å
212	G	87.8	Confident	90.5	Very high	51 Å²	51	78.9 Å²	78.9	53%	0.526	41%	0.412	S	S	.	.	T	Hydrogen-bonded Turn	trans	83.8	15.3	-178.6	0	0	0	0	0	114.7	K208 I209 A210 T214	K208-G212 PolarHBondContact O-N 2.9Å; I209-G212 PolarHBondContact O-N 2.93Å; A210-G212 VanDerWaalsContact C-N 3.3Å; G212-T214 PolarHBondContact O-N 3.28Å
213	E	88.3	Confident	90.2	Very high	73 Å²	73	80.8 Å²	80.8	34%	0.341	44%	0.437	S	S	.	.			trans	-78.2	52.7	178.6	-63.8	178.6	-154.7	0	0	112.1	K208 K211 V286	K208-E213 HydrophobicContact CB-CB 4.42Å; K208-E213 IonicContact NZ-OE2 2.67Å; K208-E213 PolarHBondContact NZ-OE2 3.44Å; K208-E213 PolarHBondContact O-N 3.06Å; K208-E213 VanDerWaalsContact O-N 3.14Å; K211-E213 HydrophobicContact CB-CG 4.43Å; E213-V286 WeakPolarHBondContact O-CG1 3.24Å
214	T	87.8	Confident	90.2	Very high	58 Å²	58	78.4 Å²	78.4	36%	0.356	43%	0.428	S	S	.	.			trans	-103.4	22.6	-174.7	56.3	0	0	0	0	113.8	I209 G212 N216 F217	I209-T214 HydrophobicContact CG1-CG2 4.45Å; I209-T214 HydrophobicContact CG2-CG2 4.17Å; G212-T214 PolarHBondContact O-N 3.28Å; T214-N216 VanDerWaalsContact C-N 3.27Å; T214-N216 PolarHBondContact O-N 3.07Å; T214-F217 PolarHBondContact O-N 3.5Å
215	Q	86.3	Confident	90.2	Very high	144 Å²	144	78.9 Å²	78.9	67%	0.673	43%	0.433	S	S	*	.	G	3₁₀ helix	trans	-56	-40.7	-174.6	-62.9	177.1	15	0	0	112.5	F217 Q218	Q215-F217 PolarHBondContact O-N 3.15Å; Q215-F217 VanDerWaalsContact O-N 3.12Å; Q215-Q218 WeakPolarHBondContact O-CG 3.33Å; Q215-Q218 PolarHBondContact O-N 3.38Å
216	N	84.3	Confident	90.1	Very high	50 Å²	50	85 Å²	85	27%	0.267	47%	0.47	S	S	.	.	G	3₁₀ helix	trans	-64.7	-14.8	178	-69.4	-18.8	0	0	0	113.9	Y72 T214 Y285 L288	Y72-N216 HydrophobicContact CD2-CB 4.3Å; Y72-N216 VanDerWaalsContact CD2-O 3.23Å; Y72-N216 WeakPolarHBondContact CD2-O 3.45Å; Y72-N216 HydrophobicContact CE2-CB 3.73Å; T214-N216 VanDerWaalsContact C-N 3.27Å; T214-N216 PolarHBondContact O-N 3.07Å; N216-Y285 VanDerWaalsContact CB-O 3.29Å; N216-Y285 WeakPolarHBondContact CB-O 3.38Å; N216-Y285 PolarHBondContact ND2-O 3.19Å; N216-L288 PolarHBondContact ND2-O 3.33Å
217	F	87.3	Confident	89.9	Confident	55 Å²	55	86.1 Å²	86.1	24%	0.241	47%	0.474	C	S	.	.	G	3₁₀ helix	trans	-102.6	10.1	179.1	-70.9	-79.9	0	0	0	114	L76 T214 Q215 P220 V282 Y285 V286	L76-F217 HydrophobicContact CD1-CE1 3.97Å; T214-F217 PolarHBondContact O-N 3.5Å; Q215-F217 PolarHBondContact O-N 3.15Å; Q215-F217 VanDerWaalsContact O-N 3.12Å; F217-P220 HydrophobicContact CD1-CB 4.46Å; F217-P220 WeakPolarHBondContact O-CD 3.26Å; F217-V282 HydrophobicContact CZ-CG1 4.39Å; F217-Y285 HydrophobicContact CZ-CD2 4.35Å; F217-V286 HydrophobicContact CD2-CG2 4.2Å; F217-V286 HydrophobicContact CE2-CB 4.5Å; F217-V286 HydrophobicContact CE2-CG2 3.51Å; F217-V286 HydrophobicContact CZ-CG2 4.44Å
218	Q	86.6	Confident	89.6	Confident	147 Å²	147	84.6 Å²	84.6	69%	0.687	47%	0.472	S	S	*	.	S	Bend	trans	-67.5	-44.4	177.9	-70.6	179.6	2.5	0	0	112	Q215 P220	Q215-Q218 WeakPolarHBondContact O-CG 3.33Å; Q215-Q218 PolarHBondContact O-N 3.38Å; Q218-P220 WeakPolarHBondContact O-CD 3.45Å
219	N	88.3	Confident	89.4	Confident	108 Å²	108	83.4 Å²	83.4	58%	0.578	47%	0.469	S	S	*	.	S	Bend	trans	-123.7	69.9	175	-66.3	-28.3	0	0	0	110.7	F221 E222	N219-F221 PolarHBondContact O-N 2.94Å; N219-F221 VanDerWaalsContact O-N 3.12Å; N219-E222 HydrophobicContact CB-CB 3.92Å; N219-E222 VanDerWaalsContact CB-OE2 3.24Å; N219-E222 WeakPolarHBondContact CB-OE2 3.28Å; N219-E222 PolarHBondContact ND2-OE2 3.49Å; N219-E222 PolarHBondContact O-N 3.49Å
220	P	90.1	Very high	89.3	Confident	35 Å²	35	81 Å²	81	23%	0.227	46%	0.459	C	S	.	.	T	Hydrogen-bonded Turn	trans	-67.2	-22.3	-165.7	25.4	-31.7	0	0	0	113.5	S71 Y72 G73 F217 Q218	S71-P220 WeakPolarHBondContact CB-O 3.2Å; S71-P220 PolarHBondContact OG-O 3.37Å; Y72-P220 PolarHBondContact N-O 3.27Å; G73-P220 WeakPolarHBondContact CA-O 3.47Å; G73-P220 PolarHBondContact N-O 2.84Å; F217-P220 HydrophobicContact CD1-CB 4.46Å; F217-P220 WeakPolarHBondContact O-CD 3.26Å; Q218-P220 WeakPolarHBondContact O-CD 3.45Å
221	F	93.8	Very high	89.3	Confident	120 Å²	120	79.2 Å²	79.2	53%	0.526	44%	0.437	S	S	.	.	T	Hydrogen-bonded Turn	trans	-102.3	0.3	-178	-64.7	-79.6	0	0	0	113.9	G73 V77 N219 G223 S224	G73-F221 VanDerWaalsContact C-CE1 3.44Å; V77-F221 HydrophobicContact CG2-CE1 4.32Å; N219-F221 PolarHBondContact O-N 2.94Å; N219-F221 VanDerWaalsContact O-N 3.12Å; F221-G223 PolarHBondContact O-N 2.9Å; F221-S224 WeakPolarHBondContact O-CB 3.5Å; F221-S224 PolarHBondContact O-N 3.4Å; F221-S224 PolarHBondContact O-OG 3.46Å
222	E	91.1	Very high	89.2	Confident	136 Å²	136	72 Å²	72	64%	0.636	41%	0.405	S	S	*	.	T	Hydrogen-bonded Turn	trans	-63.4	132.1	178.3	-172.1	171.5	-175	0	0	110.5	S71 N219 S224	S71-E222 WeakPolarHBondContact CB-O 3.39Å; N219-E222 HydrophobicContact CB-CB 3.92Å; N219-E222 VanDerWaalsContact CB-OE2 3.24Å; N219-E222 WeakPolarHBondContact CB-OE2 3.28Å; N219-E222 PolarHBondContact ND2-OE2 3.49Å; N219-E222 PolarHBondContact O-N 3.49Å; E222-S224 VanDerWaalsContact C-N 3.34Å
223	G	88.5	Confident	89.3	Confident	61 Å²	61	70.3 Å²	70.3	63%	0.629	39%	0.385	S	S	*	.	T	Hydrogen-bonded Turn	trans	80.1	7.6	-176.3	0	0	0	0	0	115.5	G70 F221 S225	G70-G223 CarbonylContact C-O 3.47Å; G70-G223 CarbonylContact O-C 3.44Å; F221-G223 PolarHBondContact O-N 2.9Å; G223-S225 PolarHBondContact O-N 3.48Å
224	S	93.6	Very high	89.6	Confident	38 Å²	38	66.9 Å²	66.9	27%	0.266	37%	0.368	S	S	.	.			trans	-52.8	126.2	177.6	-71.1	0	0	0	0	112.6	S71 F221 E222	S71-S224 PolarHBondContact OG-OG 2.93Å; F221-S224 WeakPolarHBondContact O-CB 3.5Å; F221-S224 PolarHBondContact O-N 3.4Å; F221-S224 PolarHBondContact O-OG 3.46Å; E222-S224 VanDerWaalsContact C-N 3.34Å
225	S	91.4	Very high	89.8	Confident	29 Å²	29	65.1 Å²	65.1	20%	0.203	36%	0.357	C	S	.	.			trans	-66.1	135.7	172.8	-172.7	0	0	0	0	110.7	H68 S69 L74 G223 E227 S230	H68-S225 VanDerWaalsContact O-CB 3.27Å; H68-S225 WeakPolarHBondContact O-CB 3.15Å; S69-S225 PolarHBondContact O-N 2.68Å; L74-S225 WeakPolarHBondContact CD2-O 3.16Å; G223-S225 PolarHBondContact O-N 3.48Å; S225-E227 PolarHBondContact OG-N 2.98Å; S225-S230 WeakPolarHBondContact OG-CB 3.45Å
226	T	90.5	Very high	90.1	Very high	131 Å²	131	58.4 Å²	58.4	80%	0.804	33%	0.325	S	S	*	.			trans	-107.3	-4.8	176.3	53.4	0	0	0	0	112.3	P228	T226-P228 WeakPolarHBondContact O-CD 3.35Å
227	E	89.5	Confident	90.5	Very high	118 Å²	118	56 Å²	56	55%	0.551	31%	0.313	S	S	*	.			trans	-79.6	124.8	-176.5	-170.8	-178.3	-166.3	0	0	110.8	S225 G229 S230 I231	S225-E227 PolarHBondContact OG-N 2.98Å; E227-G229 VanDerWaalsContact C-N 3.26Å; E227-G229 PolarHBondContact O-N 3.22Å; E227-S230 PolarHBondContact O-N 2.96Å; E227-S230 PolarHBondContact OE2-OG 3.22Å; E227-I231 WeakPolarHBondContact O-CG1 3.38Å; E227-I231 PolarHBondContact O-N 3.13Å; E227-I231 VanDerWaalsContact O-N 3.11Å
228	P	87.6	Confident	90.9	Very high	76 Å²	76	53.4 Å²	53.4	49%	0.494	30%	0.301	S	S	.	.	H	α-helix	trans	-57.6	-36.2	-179.6	-26.7	35.1	0	0	0	113.9	T226 I231 A232 V437	T226-P228 WeakPolarHBondContact O-CD 3.35Å; P228-I231 PolarHBondContact O-N 3.02Å; P228-A232 PolarHBondContact O-N 2.87Å; P228-V437 HydrophobicContact CB-CG1 4.26Å; P228-V437 WeakPolarHBondContact O-CG1 3.16Å
229	G	87.8	Confident	91.2	Very high	10 Å²	10	46.5 Å²	46.5	10%	0.103	27%	0.269	C	S	.	.	H	α-helix	trans	-61	-49.3	177.8	0	0	0	0	0	112.3	E227 I231 A232 L233	E227-G229 VanDerWaalsContact C-N 3.26Å; E227-G229 PolarHBondContact O-N 3.22Å; G229-I231 PolarHBondContact O-N 3.42Å; G229-A232 PolarHBondContact O-N 3.1Å; G229-L233 WeakPolarHBondContact O-CG 3.36Å; G229-L233 PolarHBondContact O-N 2.89Å
230	S	90.4	Very high	91.4	Very high	23 Å²	23	41.7 Å²	41.7	16%	0.161	24%	0.243	C	C	.	.	H	α-helix	trans	-60	-43.7	175.5	-70.1	0	0	0	0	111.8	H68 S225 E227 A232 L233 A234	H68-S230 WeakPolarHBondContact CB-O 3.23Å; S225-S230 WeakPolarHBondContact OG-CB 3.45Å; E227-S230 PolarHBondContact O-N 2.96Å; E227-S230 PolarHBondContact OE2-OG 3.22Å; S230-A232 VanDerWaalsContact C-N 3.31Å; S230-A232 PolarHBondContact O-N 3.43Å; S230-L233 PolarHBondContact O-N 3.49Å; S230-A234 WeakPolarHBondContact O-CB 3.29Å; S230-A234 PolarHBondContact O-N 2.99Å
231	I	91.9	Very high	91.6	Very high	48 Å²	48	40 Å²	40	25%	0.246	23%	0.232	C	C	.	.	H	α-helix	trans	-62.3	-39.3	177	-63.9	167.5	0	0	0	111.4	E227 P228 G229 A234 L235	E227-I231 WeakPolarHBondContact O-CG1 3.38Å; E227-I231 PolarHBondContact O-N 3.13Å; E227-I231 VanDerWaalsContact O-N 3.11Å; P228-I231 PolarHBondContact O-N 3.02Å; G229-I231 PolarHBondContact O-N 3.42Å; I231-A234 PolarHBondContact O-N 3.38Å; I231-L235 HydrophobicContact CG2-CD1 4.27Å; I231-L235 WeakPolarHBondContact O-CB 3.37Å; I231-L235 WeakPolarHBondContact O-CG 3.28Å; I231-L235 PolarHBondContact O-N 3.15Å
232	A	90.1	Very high	91.5	Very high	0 Å²	0	34.3 Å²	34.3	0%	0	21%	0.207	C	C	.	.	H	α-helix	trans	-66.5	-41.3	177.4	0	0	0	0	0	112.5	P228 G229 S230 L235 Y236 F433 V437 P438	P228-A232 PolarHBondContact O-N 2.87Å; G229-A232 PolarHBondContact O-N 3.1Å; S230-A232 VanDerWaalsContact C-N 3.31Å; S230-A232 PolarHBondContact O-N 3.43Å; A232-L235 WeakPolarHBondContact O-CB 3.33Å; A232-L235 PolarHBondContact O-N 3.13Å; A232-Y236 WeakPolarHBondContact O-CD1 3.38Å; A232-Y236 PolarHBondContact O-N 3.47Å; A232-F433 HydrophobicContact CB-CE1 4.31Å; A232-V437 HydrophobicContact CB-CB 4.02Å; A232-V437 HydrophobicContact CB-CG1 3.59Å; A232-P438 HydrophobicContact CB-CG 4.03Å
233	L	90.3	Very high	91.3	Very high	17 Å²	17	28.9 Å²	28.9	9%	0.089	18%	0.184	C	C	.	.	H	α-helix	trans	-68.1	-36.4	176	-66.1	176	0	0	0	112.4	G229 S230 Y236 S237 D442	G229-L233 WeakPolarHBondContact O-CG 3.36Å; G229-L233 PolarHBondContact O-N 2.89Å; S230-L233 PolarHBondContact O-N 3.49Å; L233-Y236 HydrophobicContact CD2-CD2 4.39Å; L233-Y236 WeakPolarHBondContact O-CB 3.31Å; L233-Y236 PolarHBondContact O-N 3.28Å; L233-S237 PolarHBondContact O-N 2.89Å; L233-S237 VanDerWaalsContact O-N 3.08Å; L233-S237 PolarHBondContact O-OG 2.9Å; L233-D442 HydrophobicContact CD2-CB 4.18Å
234	A	94	Very high	91.1	Very high	0 Å²	0	26.6 Å²	26.6	0%	0	16%	0.16	C	C	.	.	H	α-helix	trans	-62.1	-44.3	170.1	0	0	0	0	0	111.2	V65 H68 I78 S230 I231 Y236 S237 A238	V65-A234 HydrophobicContact CG1-CB 4.48Å; H68-A234 HydrophobicContact CB-CB 3.72Å; I78-A234 HydrophobicContact CD1-CB 3.6Å; I78-A234 HydrophobicContact CG2-CB 4.19Å; S230-A234 WeakPolarHBondContact O-CB 3.29Å; S230-A234 PolarHBondContact O-N 2.99Å; I231-A234 PolarHBondContact O-N 3.38Å; A234-Y236 VanDerWaalsContact C-N 3.34Å; A234-Y236 PolarHBondContact O-N 3.47Å; A234-S237 PolarHBondContact O-N 3.37Å; A234-A238 PolarHBondContact O-N 3.09Å
235	L	93.4	Very high	90.8	Very high	22 Å²	22	24.8 Å²	24.8	12%	0.115	15%	0.148	C	C	.	.	H	α-helix	trans	-61.9	-39.9	174.2	-82.7	166.6	0	0	0	111.8	I78 L81 I231 A232 S237 A238 L239 F433 L434	I78-L235 HydrophobicContact CG2-CD2 3.9Å; I78-L235 HydrophobicContact CG2-CG 4.05Å; L81-L235 HydrophobicContact CB-CD2 4.39Å; I231-L235 HydrophobicContact CG2-CD1 4.27Å; I231-L235 WeakPolarHBondContact O-CB 3.37Å; I231-L235 WeakPolarHBondContact O-CG 3.28Å; I231-L235 PolarHBondContact O-N 3.15Å; A232-L235 WeakPolarHBondContact O-CB 3.33Å; A232-L235 PolarHBondContact O-N 3.13Å; L235-S237 VanDerWaalsContact C-N 3.34Å; L235-S237 PolarHBondContact O-N 2.91Å; L235-A238 PolarHBondContact O-N 3.01Å; L235-L239 WeakPolarHBondContact O-CB 3.38Å; L235-L239 WeakPolarHBondContact O-CG 3.46Å; L235-L239 PolarHBondContact O-N 3.13Å; L235-F433 HydrophobicContact CD1-CE1 4.18Å; L235-L434 HydrophobicContact CB-CD2 4.06Å; L235-L434 HydrophobicContact CD1-CD2 4.35Å
236	Y	91.6	Very high	90.6	Very high	2 Å²	2	23.7 Å²	23.7	1%	0.008	14%	0.14	C	C	.	.	H	α-helix	trans	-57.1	-47.3	174.2	-83.9	15.1	0	0	0	111.9	A232 L233 A234 A238 L239 F240 F390 L434 P438	A232-Y236 WeakPolarHBondContact O-CD1 3.38Å; A232-Y236 PolarHBondContact O-N 3.47Å; L233-Y236 HydrophobicContact CD2-CD2 4.39Å; L233-Y236 WeakPolarHBondContact O-CB 3.31Å; L233-Y236 PolarHBondContact O-N 3.28Å; A234-Y236 VanDerWaalsContact C-N 3.34Å; A234-Y236 PolarHBondContact O-N 3.47Å; Y236-A238 PolarHBondContact O-N 3.49Å; Y236-L239 PolarHBondContact O-N 3.44Å; Y236-F240 WeakPolarHBondContact O-CB 3.46Å; Y236-F240 PolarHBondContact O-N 3.41Å; Y236-F390 HydrophobicContact CE2-CB 4.25Å; Y236-F390 WeakPolarHBondContact OH-CA 3.46Å; Y236-L434 HydrophobicContact CD1-CD2 4.05Å; Y236-L434 HydrophobicContact CE1-CB 4.06Å; Y236-L434 HydrophobicContact CE1-CD2 3.96Å; Y236-L434 VanDerWaalsContact CE1-O 3.27Å; Y236-L434 WeakPolarHBondContact CE1-O 3.31Å; Y236-L434 VanDerWaalsContact CZ-O 3.25Å; Y236-L434 PolarHBondContact OH-O 2.91Å; Y236-P438 HydrophobicContact CE1-CG 3.95Å; Y236-P438 HydrophobicContact CE2-CB 4.07Å; Y236-P438 HydrophobicContact CE2-CG 3.93Å; Y236-P438 WeakPolarHBondContact OH-CG 3.39Å
237	S	92.9	Very high	90.1	Very high	1 Å²	1	18.8 Å²	18.8	1%	0.007	11%	0.11	C	C	.	.	H	α-helix	trans	-60.2	-47.3	176.6	-63.5	0	0	0	0	111.4	S61 L233 A234 L235 L239 F240 S241	S61-S237 WeakPolarHBondContact CB-O 3.23Å; S61-S237 PolarHBondContact OG-O 3.2Å; L233-S237 PolarHBondContact O-N 2.89Å; L233-S237 VanDerWaalsContact O-N 3.08Å; L233-S237 PolarHBondContact O-OG 2.9Å; A234-S237 PolarHBondContact O-N 3.37Å; L235-S237 VanDerWaalsContact C-N 3.34Å; L235-S237 PolarHBondContact O-N 2.91Å; S237-L239 PolarHBondContact O-N 2.94Å; S237-F240 PolarHBondContact O-N 3.38Å; S237-S241 PolarHBondContact O-OG 3.32Å
238	A	95.2	Very high	89.7	Confident	0 Å²	0	13.2 Å²	13.2	0%	0	8%	0.084	C	C	.	.	H	α-helix	trans	-61.3	-48	177.2	0	0	0	0	0	111.5	V65 I78 W79 A234 L235 Y236 F240 S241 Y242	V65-A238 HydrophobicContact CG2-CB 3.91Å; I78-A238 HydrophobicContact CG2-CB 4.09Å; W79-A238 HydrophobicContact CD2-CB 4.38Å; W79-A238 HydrophobicContact CE3-CB 4.43Å; A234-A238 PolarHBondContact O-N 3.09Å; L235-A238 PolarHBondContact O-N 3.01Å; Y236-A238 PolarHBondContact O-N 3.49Å; A238-F240 VanDerWaalsContact C-N 3.34Å; A238-F240 PolarHBondContact O-N 3.28Å; A238-S241 VanDerWaalsContact O-CB 3.3Å; A238-S241 WeakPolarHBondContact O-CB 3.48Å; A238-S241 PolarHBondContact O-N 3.4Å; A238-Y242 VanDerWaalsContact O-CD2 3.29Å; A238-Y242 WeakPolarHBondContact O-CD2 3.46Å; A238-Y242 PolarHBondContact O-N 3.46Å
239	L	93.3	Very high	89.5	Confident	1 Å²	1	9.6 Å²	9.6	1%	0.005	6%	0.06	C	C	.	.	H	α-helix	trans	-67.6	-30.2	-176.5	-73.6	177.4	0	0	0	113.3	F85 L235 Y236 S237 S241 Y242 S243 W393 L434	F85-L239 HydrophobicContact CD1-CD1 4.01Å; F85-L239 HydrophobicContact CD1-CD2 3.44Å; F85-L239 VanDerWaalsContact CD1-CD2 3.44Å; F85-L239 HydrophobicContact CD1-CG 4.4Å; F85-L239 HydrophobicContact CE1-CD1 3.99Å; F85-L239 HydrophobicContact CE1-CD2 4.04Å; F85-L239 HydrophobicContact CG-CD2 4.36Å; L235-L239 WeakPolarHBondContact O-CB 3.38Å; L235-L239 WeakPolarHBondContact O-CG 3.46Å; L235-L239 PolarHBondContact O-N 3.13Å; Y236-L239 PolarHBondContact O-N 3.44Å; S237-L239 PolarHBondContact O-N 2.94Å; L239-S241 PolarHBondContact O-N 3.42Å; L239-Y242 CarbonylContact O-C 3.34Å; L239-Y242 PolarHBondContact O-N 3.02Å; L239-Y242 VanDerWaalsContact O-N 3.08Å; L239-S243 PolarHBondContact O-N 3.43Å; L239-W393 HydrophobicContact CB-CH2 4.43Å; L239-W393 HydrophobicContact CB-CZ2 3.52Å; L239-W393 HydrophobicContact CD1-CZ2 4.42Å; L239-W393 HydrophobicContact CD2-CZ2 4.36Å; L239-W393 HydrophobicContact CG-CZ2 4.32Å; L239-W393 WeakPolarHBondContact O-CZ2 3.42Å; L239-L434 HydrophobicContact CD1-CD1 3.44Å; L239-L434 VanDerWaalsContact CD1-CD1 3.44Å; L239-L434 HydrophobicContact CD1-CD2 4.09Å; L239-L434 HydrophobicContact CD1-CG 4.43Å
240	F	92.8	Very high	89	Confident	7 Å²	7	11.5 Å²	11.5	3%	0.031	7%	0.066	C	C	.	.	H	α-helix	trans	-55	-42.9	168.7	178.1	-105.2	0	0	0	111.1	V137 Y236 S237 A238 Y242 S243 I385 F388	V137-F240 HydrophobicContact CB-CZ 3.95Å; V137-F240 HydrophobicContact CG1-CE1 3.64Å; V137-F240 HydrophobicContact CG1-CE2 4.41Å; V137-F240 HydrophobicContact CG1-CZ 3.45Å; V137-F240 VanDerWaalsContact CG1-CZ 3.45Å; Y236-F240 WeakPolarHBondContact O-CB 3.46Å; Y236-F240 PolarHBondContact O-N 3.41Å; S237-F240 PolarHBondContact O-N 3.38Å; A238-F240 VanDerWaalsContact C-N 3.34Å; A238-F240 PolarHBondContact O-N 3.28Å; F240-Y242 VanDerWaalsContact C-N 3.3Å; F240-Y242 PolarHBondContact O-N 2.88Å; F240-S243 WeakPolarHBondContact O-CB 3.25Å; F240-S243 PolarHBondContact O-N 2.79Å; F240-S243 PolarHBondContact O-OG 3.19Å; F240-I385 HydrophobicContact CB-CG2 3.88Å; F240-I385 HydrophobicContact CD1-CD1 4.2Å; F240-I385 HydrophobicContact CD1-CG1 4.2Å; F240-I385 HydrophobicContact CD2-CG1 4.36Å; F240-I385 HydrophobicContact CD2-CG2 4.36Å; F240-I385 HydrophobicContact CE1-CD1 4.45Å; F240-I385 HydrophobicContact CE1-CG1 4.35Å; F240-I385 HydrophobicContact CG-CG1 4.21Å; F240-I385 HydrophobicContact CG-CG2 4.06Å; F240-F388 AromaticContact CD2-CD1 3.58Å; F240-F388 HydrophobicContact CD2-CD1 3.58Å; F240-F388 AromaticContact CD2-CE1 3.74Å; F240-F388 HydrophobicContact CD2-CE1 3.74Å; F240-F388 HydrophobicContact CD2-CG 4.34Å; F240-F388 HydrophobicContact CE2-CD1 4.05Å; F240-F388 HydrophobicContact CE2-CE1 4.25Å; F240-F388 HydrophobicContact CE2-CG 4.41Å
241	S	93.3	Very high	88.2	Confident	1 Å²	1	11 Å²	11	1%	0.007	6%	0.062	C	C	.	.	H	α-helix	trans	-70.1	-27.2	177.1	-43.6	0	0	0	0	113.5	G57 S61 W79 S237 A238 L239 S243 Y277	G57-S241 PolarHBondContact O-OG 3.3Å; S61-S241 WeakPolarHBondContact CB-OG 3.29Å; S61-S241 PolarHBondContact OG-OG 2.87Å; W79-S241 WeakPolarHBondContact CH2-OG 3.49Å; S237-S241 PolarHBondContact O-OG 3.32Å; A238-S241 VanDerWaalsContact O-CB 3.3Å; A238-S241 WeakPolarHBondContact O-CB 3.48Å; A238-S241 PolarHBondContact O-N 3.4Å; L239-S241 PolarHBondContact O-N 3.42Å; S241-S243 VanDerWaalsContact C-N 3.35Å; S241-Y277 VanDerWaalsContact O-CE2 3.23Å; S241-Y277 WeakPolarHBondContact O-CE2 3.23Å; S241-Y277 PolarHBondContact O-OH 2.92Å
242	Y	91.9	Very high	87.6	Confident	0 Å²	0	8.9 Å²	8.9	0%	0	5%	0.051	C	C	.	.	H	α-helix	trans	-87	-2.9	174.6	-73.7	-75.2	0	0	0	113	M53 W79 S86 A238 L239 F240 V273 Y277	M53-Y242 HydrophobicContact CE-CD1 3.79Å; M53-Y242 VanDerWaalsContact CE-O 3.28Å; M53-Y242 WeakPolarHBondContact CE-O 3.4Å; W79-Y242 HydrophobicContact CE3-CD2 4.5Å; W79-Y242 AromaticContact CE3-CE2 3.65Å; W79-Y242 HydrophobicContact CE3-CE2 3.65Å; W79-Y242 HydrophobicContact CZ3-CE2 4.06Å; W79-Y242 WeakPolarHBondContact O-CE2 3.39Å; W79-Y242 PolarHBondContact O-OH 3.34Å; S86-Y242 VanDerWaalsContact OG-CB 3.27Å; S86-Y242 WeakPolarHBondContact OG-CB 3.47Å; A238-Y242 VanDerWaalsContact O-CD2 3.29Å; A238-Y242 WeakPolarHBondContact O-CD2 3.46Å; A238-Y242 PolarHBondContact O-N 3.46Å; L239-Y242 CarbonylContact O-C 3.34Å; L239-Y242 PolarHBondContact O-N 3.02Å; L239-Y242 VanDerWaalsContact O-N 3.08Å; F240-Y242 VanDerWaalsContact C-N 3.3Å; F240-Y242 PolarHBondContact O-N 2.88Å; Y242-V273 HydrophobicContact CD1-CG1 4.24Å; Y242-V273 HydrophobicContact CE1-CG1 4.18Å; Y242-Y277 AromaticContact CD1-CD2 3.99Å; Y242-Y277 HydrophobicContact CD1-CD2 3.99Å; Y242-Y277 AromaticContact CD1-CE2 3.94Å; Y242-Y277 HydrophobicContact CD1-CE2 3.94Å; Y242-Y277 HydrophobicContact CD2-CD2 4.39Å; Y242-Y277 AromaticContact CE1-CD2 3.54Å; Y242-Y277 HydrophobicContact CE1-CD2 3.54Å; Y242-Y277 AromaticContact CE1-CE2 3.96Å; Y242-Y277 HydrophobicContact CE1-CE2 3.96Å; Y242-Y277 AromaticContact CE2-CD2 3.98Å; Y242-Y277 HydrophobicContact CE2-CD2 3.98Å; Y242-Y277 HydrophobicContact CG-CD2 4.39Å; Y242-Y277 HydrophobicContact CG-CE2 4.24Å; Y242-Y277 AromaticContact CZ-CD2 3.52Å
243	S	87.9	Confident	86.9	Confident	22 Å²	22	12.4 Å²	12.4	15%	0.154	7%	0.067	C	C	.	.	T	Hydrogen-bonded Turn	trans	-65.9	156.3	177.9	70.4	0	0	0	0	112	L239 F240 S241	L239-S243 PolarHBondContact O-N 3.43Å; F240-S243 WeakPolarHBondContact O-CB 3.25Å; F240-S243 PolarHBondContact O-N 2.79Å; F240-S243 PolarHBondContact O-OG 3.19Å; S241-S243 VanDerWaalsContact C-N 3.35Å
244	G	83.9	Confident	86.5	Confident	12 Å²	12	13.2 Å²	13.2	12%	0.124	7%	0.07	C	C	.	.	T	Hydrogen-bonded Turn	trans	97.5	-1.7	177.1	0	0	0	0	0	115.9	D246 T247	G244-D246 WeakPolarHBondContact CA-OD1 3.38Å; G244-D246 PolarHBondContact O-N 3.22Å; G244-T247 WeakPolarHBondContact O-CB 3.33Å; G244-T247 PolarHBondContact O-N 2.89Å; G244-T247 VanDerWaalsContact O-N 3.1Å; G244-T247 PolarHBondContact O-OG1 2.94Å
245	W	87.6	Confident	86	Confident	0 Å²	0	13.4 Å²	13.4	0%	0	7%	0.071	C	C	.	.	T	Hydrogen-bonded Turn	trans	-62.1	-24.1	171.1	54.9	-106.3	0	0	0	112.9	M53 A90 Y93 T247 M270 V396	M53-W245 HydrophobicContact CE-CB 4.24Å; M53-W245 HydrophobicContact CG-CB 4.29Å; M53-W245 HydrophobicContact SD-CB 3.77Å; A90-W245 VanDerWaalsContact CA-CE3 3.45Å; A90-W245 HydrophobicContact CB-CB 4.41Å; A90-W245 HydrophobicContact CB-CD2 3.75Å; A90-W245 HydrophobicContact CB-CE3 3.53Å; A90-W245 HydrophobicContact CB-CG 4.13Å; A90-W245 HydrophobicContact CB-CZ3 4.14Å; Y93-W245 VanDerWaalsContact CB-CZ3 3.48Å; Y93-W245 HydrophobicContact CD1-CH2 4.09Å; Y93-W245 AromaticContact CD1-CZ3 3.67Å; Y93-W245 HydrophobicContact CD1-CZ3 3.67Å; Y93-W245 AromaticContact CD2-CH2 3.54Å; Y93-W245 HydrophobicContact CD2-CH2 3.54Å; Y93-W245 AromaticContact CD2-CZ3 3.75Å; Y93-W245 HydrophobicContact CD2-CZ3 3.75Å; Y93-W245 HydrophobicContact CE1-CH2 4.37Å; Y93-W245 HydrophobicContact CE1-CZ3 4.31Å; Y93-W245 AromaticContact CE2-CH2 3.85Å; Y93-W245 HydrophobicContact CE2-CH2 3.85Å; Y93-W245 HydrophobicContact CE2-CZ3 4.37Å; Y93-W245 AromaticContact CG-CH2 3.68Å; Y93-W245 HydrophobicContact CG-CH2 3.68Å; Y93-W245 AromaticContact CG-CZ3 3.36Å; Y93-W245 HydrophobicContact CG-CZ3 3.36Å; W245-T247 PolarHBondContact O-N 3.46Å; W245-M270 HydrophobicContact CB-SD 3.59Å; W245-M270 VanDerWaalsContact CB-SD 3.59Å; W245-M270 HydrophobicContact CG-SD 4.13Å; W245-V396 HydrophobicContact CH2-CG1 3.97Å; W245-V396 HydrophobicContact CZ2-CG1 4.01Å
246	D	86.5	Confident	85.7	Confident	7 Å²	7	16.2 Å²	16.2	4%	0.037	8%	0.084	C	C	.	.	T	Hydrogen-bonded Turn	trans	-78.1	-1.1	176.6	60.1	-23.6	0	0	0	112.9	Y93 G244 L248 N249 F250 Y392	Y93-D246 HydrophobicContact CD1-CB 3.97Å; Y93-D246 HydrophobicContact CE1-CB 4.04Å; G244-D246 WeakPolarHBondContact CA-OD1 3.38Å; G244-D246 PolarHBondContact O-N 3.22Å; D246-L248 VanDerWaalsContact C-N 3.32Å; D246-L248 PolarHBondContact O-N 3.18Å; D246-N249 VanDerWaalsContact O-CB 3.24Å; D246-N249 WeakPolarHBondContact O-CB 3.22Å; D246-N249 PolarHBondContact O-N 3.44Å; D246-F250 WeakPolarHBondContact O-CD2 3.39Å; D246-Y392 PolarHBondContact OD1-OH 3.39Å; D246-Y392 PolarHBondContact OD2-OH 3.37Å
247	T	80.1	Confident	85.5	Confident	28 Å²	28	21.3 Å²	21.3	17%	0.172	11%	0.112	C	C	.	.	H	α-helix	trans	-62.3	-37.1	-176.7	-46.8	0	0	0	0	112.8	L48 N52 G244 W245 N249 F250	L48-T247 HydrophobicContact CD2-CG2 3.89Å; N52-T247 WeakPolarHBondContact ND2-CB 3.3Å; N52-T247 WeakPolarHBondContact ND2-CG2 3.43Å; N52-T247 PolarHBondContact ND2-OG1 3.07Å; G244-T247 WeakPolarHBondContact O-CB 3.33Å; G244-T247 PolarHBondContact O-N 2.89Å; G244-T247 VanDerWaalsContact O-N 3.1Å; G244-T247 PolarHBondContact O-OG1 2.94Å; W245-T247 PolarHBondContact O-N 3.46Å; T247-N249 PolarHBondContact O-N 3.22Å; T247-F250 WeakPolarHBondContact O-CB 3.27Å; T247-F250 PolarHBondContact O-N 3.47Å
248	L	80.4	Confident	85.2	Confident	1 Å²	1	22.1 Å²	22.1	1%	0.005	12%	0.117	C	C	.	.	H	α-helix	trans	-63.6	-25.5	176.3	-77.3	-171.7	0	0	0	113	L48 I49 D246 F250 V251 T252 I255 L262 A265	L48-L248 HydrophobicContact CB-CD2 4.25Å; L48-L248 HydrophobicContact CD1-CD2 3.97Å; L48-L248 HydrophobicContact CD2-CD2 3.7Å; L48-L248 HydrophobicContact CD2-CG 4.12Å; L48-L248 HydrophobicContact CG-CD2 4.19Å; I49-L248 HydrophobicContact CD1-CD1 3.4Å; I49-L248 HydrophobicContact CD1-CG 3.95Å; I49-L248 HydrophobicContact CG1-CD1 3.63Å; I49-L248 HydrophobicContact CG1-CG 3.69Å; D246-L248 VanDerWaalsContact C-N 3.32Å; D246-L248 PolarHBondContact O-N 3.18Å; L248-F250 PolarHBondContact O-N 3.46Å; L248-V251 HydrophobicContact CD2-CG2 4.1Å; L248-V251 CarbonylContact O-C 3.51Å; L248-V251 PolarHBondContact O-N 3.31Å; L248-T252 PolarHBondContact O-N 3.34Å; L248-T252 PolarHBondContact O-OG1 2.92Å; L248-T252 VanDerWaalsContact O-OG1 3.05Å; L248-I255 HydrophobicContact CB-CD1 4.17Å; L248-I255 HydrophobicContact CD2-CD1 4.19Å; L248-L262 HydrophobicContact CB-CD1 3.55Å; L248-L262 HydrophobicContact CD1-CD1 4.2Å; L248-A265 HydrophobicContact CD1-CB 3.65Å
249	N	84.7	Confident	84.8	Confident	0 Å²	0	27.4 Å²	27.4	0%	0	14%	0.141	C	C	.	.	H	α-helix	trans	-68.3	-22.8	175.3	-67.2	97.1	0	0	0	112.5	Y93 A105 Y109 D246 T247 T252	Y93-N249 HydrophobicContact CD1-CB 4.43Å; Y93-N249 PolarHBondContact O-ND2 3.45Å; A105-N249 HydrophobicContact CB-CB 3.74Å; Y109-N249 WeakPolarHBondContact OH-CB 3.34Å; Y109-N249 PolarHBondContact OH-ND2 3.47Å; D246-N249 VanDerWaalsContact O-CB 3.24Å; D246-N249 WeakPolarHBondContact O-CB 3.22Å; D246-N249 PolarHBondContact O-N 3.44Å; T247-N249 PolarHBondContact O-N 3.22Å; N249-T252 WeakPolarHBondContact CA-OG1 3.37Å; N249-T252 PolarHBondContact O-OG1 2.99Å
250	F	75.9	Confident	84.7	Confident	50 Å²	50	35.5 Å²	35.5	22%	0.219	17%	0.172	C	C	.	.	H	α-helix	trans	-77.2	-23.8	175	-70.2	-89.4	0	0	0	113	A105 D246 T247 L248	A105-F250 HydrophobicContact CB-CD1 3.73Å; A105-F250 HydrophobicContact CB-CD2 3.59Å; A105-F250 HydrophobicContact CB-CE1 3.69Å; A105-F250 HydrophobicContact CB-CE2 3.57Å; A105-F250 HydrophobicContact CB-CG 3.7Å; A105-F250 HydrophobicContact CB-CZ 3.63Å; D246-F250 WeakPolarHBondContact O-CD2 3.39Å; T247-F250 WeakPolarHBondContact O-CB 3.27Å; T247-F250 PolarHBondContact O-N 3.47Å; L248-F250 PolarHBondContact O-N 3.46Å
251	V	74.6	Confident	84.6	Confident	13 Å²	13	36.1 Å²	36.1	8%	0.079	18%	0.175	C	C	.	.	T	Hydrogen-bonded Turn	trans	-115.5	25.9	-176.8	-65.2	0	0	0	0	112	I40 L248 E253 E254 I255	I40-V251 HydrophobicContact CD1-CB 4.03Å; I40-V251 HydrophobicContact CD1-CG2 3.78Å; L248-V251 HydrophobicContact CD2-CG2 4.1Å; L248-V251 CarbonylContact O-C 3.51Å; L248-V251 PolarHBondContact O-N 3.31Å; V251-E253 PolarHBondContact O-N 3.04Å; V251-E254 HydrophobicContact CB-CB 4.39Å; V251-E254 HydrophobicContact CB-CG 4.48Å; V251-E254 WeakPolarHBondContact O-CB 3.4Å; V251-E254 PolarHBondContact O-N 2.82Å; V251-I255 WeakPolarHBondContact O-CG1 3.39Å; V251-I255 PolarHBondContact O-N 2.9Å
252	T	78.3	Confident	84.4	Confident	2 Å²	2	36 Å²	36	1%	0.012	18%	0.175	C	C	.	.	G	3₁₀ helix	trans	-61.2	-31.2	-175.2	-62.3	0	0	0	0	112.9	L248 N249 E254 I255 P258	L248-T252 PolarHBondContact O-N 3.34Å; L248-T252 PolarHBondContact O-OG1 2.92Å; L248-T252 VanDerWaalsContact O-OG1 3.05Å; N249-T252 WeakPolarHBondContact CA-OG1 3.37Å; N249-T252 PolarHBondContact O-OG1 2.99Å; T252-E254 PolarHBondContact O-N 3.11Å; T252-I255 PolarHBondContact O-N 3.25Å; T252-P258 HydrophobicContact CG2-CB 3.99Å
253	E	77.3	Confident	84.3	Confident	74 Å²	74	37.2 Å²	37.2	35%	0.346	18%	0.182	S	C	.	.	G	3₁₀ helix	trans	-65.1	-26	174.7	-67.7	172.7	-177.9	0	0	113.1	R38 T101 K102 S103 V251	R38-E253 WeakPolarHBondContact CG-O 3.46Å; T101-E253 WeakPolarHBondContact O-CG 3.28Å; K102-E253 WeakPolarHBondContact CA-OE1 3.45Å; S103-E253 PolarHBondContact N-OE1 3.2Å; S103-E253 PolarHBondContact OG-OE1 3.5Å; S103-E253 PolarHBondContact OG-OE2 3.07Å; V251-E253 PolarHBondContact O-N 3.04Å
254	E	81.3	Confident	84.4	Confident	34 Å²	34	39.3 Å²	39.3	16%	0.159	19%	0.192	C	C	.	.	G	3₁₀ helix	trans	-88.9	-8.7	-179.7	-56.5	177.8	-146.8	0	0	112.4	M36 R38 E39 I40 V251 T252 R336	M36-E254 HydrophobicContact CB-CG 4.27Å; M36-E254 HydrophobicContact CE-CG 3.83Å; M36-E254 VanDerWaalsContact CE-OE1 3.24Å; M36-E254 WeakPolarHBondContact CE-OE1 3.24Å; R38-E254 CarbonylContact C-O 3.18Å; R38-E254 WeakPolarHBondContact CA-O 3.44Å; E39-E254 PolarHBondContact N-O 3.13Å; I40-E254 HydrophobicContact CD1-CB 3.74Å; I40-E254 HydrophobicContact CG1-CB 4.09Å; I40-E254 PolarHBondContact N-O 2.75Å; V251-E254 HydrophobicContact CB-CB 4.39Å; V251-E254 HydrophobicContact CB-CG 4.48Å; V251-E254 WeakPolarHBondContact O-CB 3.4Å; V251-E254 PolarHBondContact O-N 2.82Å; T252-E254 PolarHBondContact O-N 3.11Å; E254-R336 IonicContact OE1-CZ 2.99Å; E254-R336 IonicContact OE1-NH1 3.99Å; E254-R336 PolarHBondContact OE1-NH1 2.75Å
255	I	83.9	Confident	84.8	Confident	4 Å²	4	38.8 Å²	38.8	2%	0.021	19%	0.186	C	C	.	.	B	Isolated β-bridge	trans	-81	133.2	-177	-63.3	173.9	0	0	0	111.4	I40 L248 V251 T252 P258 N261 L262	I40-I255 HydrophobicContact CB-CG1 4.23Å; I40-I255 HydrophobicContact CG2-CG1 4.27Å; L248-I255 HydrophobicContact CB-CD1 4.17Å; L248-I255 HydrophobicContact CD2-CD1 4.19Å; V251-I255 WeakPolarHBondContact O-CG1 3.39Å; V251-I255 PolarHBondContact O-N 2.9Å; T252-I255 PolarHBondContact O-N 3.25Å; I255-P258 HydrophobicContact CB-CB 4.35Å; I255-P258 HydrophobicContact CG2-CB 4.28Å; I255-N261 HydrophobicContact CG2-CB 4.05Å; I255-L262 HydrophobicContact CD1-CD1 4.05Å
256	Q	86.6	Confident	84.9	Confident	81 Å²	81	38.9 Å²	38.9	38%	0.379	19%	0.186	S	C	.	.	S	Bend	trans	-70.4	127.7	168.6	-66.1	178.7	-2.6	0	0	109.7	R38 I40 N261	R38-Q256 HydrophobicContact CB-CG 4.31Å; R38-Q256 VanDerWaalsContact O-CG 3.23Å; R38-Q256 WeakPolarHBondContact O-CG 3.39Å; R38-Q256 PolarHBondContact O-NE2 3.2Å; I40-Q256 PolarHBondContact O-N 3.17Å; Q256-N261 WeakPolarHBondContact O-CB 3.35Å; Q256-N261 VanDerWaalsContact O-CG 3.31Å; Q256-N261 PolarHBondContact O-ND2 3.33Å
257	N	87.6	Confident	85.1	Confident	110 Å²	110	41.1 Å²	41.1	59%	0.588	21%	0.206	S	C	*	.	S	Bend	trans	47.2	62.8	180	-62.1	-32.7	0	0	0	113.1	E259 R260 N261	N257-E259 PolarHBondContact O-N 2.92Å; N257-R260 PolarHBondContact O-N 3.35Å; N257-R260 VanDerWaalsContact O-N 3.08Å; N257-N261 WeakPolarHBondContact O-CB 3.28Å; N257-N261 PolarHBondContact O-N 2.79Å
258	P	85.6	Confident	85.6	Confident	17 Å²	17	43.1 Å²	43.1	11%	0.11	22%	0.215	C	C	.	.	H	α-helix	trans	-57.9	-35.8	-170.9	23.3	-33.3	0	0	0	112.8	T252 I255 R260 L262 P263	T252-P258 HydrophobicContact CG2-CB 3.99Å; I255-P258 HydrophobicContact CB-CB 4.35Å; I255-P258 HydrophobicContact CG2-CB 4.28Å; P258-R260 PolarHBondContact O-N 3.46Å; P258-R260 VanDerWaalsContact O-N 3.17Å; P258-L262 WeakPolarHBondContact O-CB 3.42Å; P258-L262 PolarHBondContact O-N 3Å; P258-P263 WeakPolarHBondContact O-CD 3.4Å
259	E	88.1	Confident	86.2	Confident	111 Å²	111	43.1 Å²	43.1	52%	0.519	22%	0.215	S	C	.	.	H	α-helix	trans	-56.2	-33.8	178.7	-59	-176.2	179.2	0	0	113.9	N257 P263 P416	N257-E259 PolarHBondContact O-N 2.92Å; E259-P263 WeakPolarHBondContact O-CD 3.35Å; E259-P263 WeakPolarHBondContact O-CG 3.33Å; E259-P416 HydrophobicContact CB-CB 3.91Å; E259-P416 VanDerWaalsContact CD-CG 3.49Å; E259-P416 HydrophobicContact CG-CB 3.63Å; E259-P416 HydrophobicContact CG-CG 3.72Å; E259-P416 WeakPolarHBondContact OE1-CG 3.19Å
260	R	89.9	Confident	86.5	Confident	172 Å²	172	43.2 Å²	43.2	65%	0.649	22%	0.215	S	C	*	.	H	α-helix	trans	-99.7	-45.7	179.5	176.9	178.8	173.3	-168.5	-1.2	111.8	N257 P258 P263 L264	N257-R260 PolarHBondContact O-N 3.35Å; N257-R260 VanDerWaalsContact O-N 3.08Å; P258-R260 PolarHBondContact O-N 3.46Å; P258-R260 VanDerWaalsContact O-N 3.17Å; R260-P263 WeakPolarHBondContact O-CD 3.14Å; R260-L264 HydrophobicContact CG-CD1 3.65Å; R260-L264 WeakPolarHBondContact O-CB 3.48Å; R260-L264 WeakPolarHBondContact O-CD1 3.29Å; R260-L264 VanDerWaalsContact O-CG 3.22Å; R260-L264 WeakPolarHBondContact O-CG 3.49Å; R260-L264 PolarHBondContact O-N 3.02Å
261	N	90.6	Very high	87.3	Confident	19 Å²	19	43.7 Å²	43.7	10%	0.102	22%	0.223	C	C	.	.	H	α-helix	trans	-78.4	-33.6	-169	-74.2	-5.4	0	0	0	112.6	L42 I255 Q256 N257 A265	L42-N261 HydrophobicContact CB-CB 4.32Å; L42-N261 HydrophobicContact CD1-CB 4.35Å; L42-N261 WeakPolarHBondContact CD1-O 3.27Å; I255-N261 HydrophobicContact CG2-CB 4.05Å; Q256-N261 WeakPolarHBondContact O-CB 3.35Å; Q256-N261 VanDerWaalsContact O-CG 3.31Å; Q256-N261 PolarHBondContact O-ND2 3.33Å; N257-N261 WeakPolarHBondContact O-CB 3.28Å; N257-N261 PolarHBondContact O-N 2.79Å; N261-A265 WeakPolarHBondContact O-CB 3.38Å; N261-A265 PolarHBondContact O-N 3.05Å
262	L	88.8	Confident	88.1	Confident	0 Å²	0	46.3 Å²	46.3	0%	0	24%	0.236	C	C	.	.	H	α-helix	trans	-64.5	-51	178	177.5	71.1	0	0	0	111.7	T98 L248 I255 P258 L264 A265 I266	T98-L262 HydrophobicContact CG2-CD2 4.26Å; L248-L262 HydrophobicContact CB-CD1 3.55Å; L248-L262 HydrophobicContact CD1-CD1 4.2Å; I255-L262 HydrophobicContact CD1-CD1 4.05Å; P258-L262 WeakPolarHBondContact O-CB 3.42Å; P258-L262 PolarHBondContact O-N 3Å; L262-L264 PolarHBondContact O-N 3.29Å; L262-A265 PolarHBondContact O-N 3.43Å; L262-I266 HydrophobicContact CD1-CD1 4.2Å; L262-I266 HydrophobicContact CG-CD1 4.33Å; L262-I266 WeakPolarHBondContact O-CG1 3.31Å; L262-I266 PolarHBondContact O-N 3.41Å
263	P	90.3	Very high	88.8	Confident	24 Å²	24	46.2 Å²	46.2	16%	0.156	24%	0.236	C	C	.	.	H	α-helix	trans	-64.5	-39.7	177.7	-20.4	32.2	0	0	0	113.1	A94 T98 P258 E259 R260 I266 A267 V417	A94-P263 HydrophobicContact CB-CB 4.29Å; A94-P263 HydrophobicContact CB-CG 4.3Å; T98-P263 HydrophobicContact CG2-CG 4.35Å; P258-P263 WeakPolarHBondContact O-CD 3.4Å; E259-P263 WeakPolarHBondContact O-CD 3.35Å; E259-P263 WeakPolarHBondContact O-CG 3.33Å; R260-P263 WeakPolarHBondContact O-CD 3.14Å; P263-I266 PolarHBondContact O-N 2.79Å; P263-A267 VanDerWaalsContact O-CB 3.28Å; P263-A267 WeakPolarHBondContact O-CB 3.26Å; P263-A267 PolarHBondContact O-N 3.43Å; P263-V417 HydrophobicContact CG-CG2 3.58Å
264	L	90.9	Very high	89.6	Confident	66 Å²	66	43.6 Å²	43.6	35%	0.346	23%	0.225	S	C	.	.	H	α-helix	trans	-65.8	-41.5	178.7	-74.5	174.8	0	0	0	112	L42 R260 L262 I266 A267 I268	L42-L264 HydrophobicContact CD1-CB 3.83Å; L42-L264 HydrophobicContact CD2-CB 4.4Å; L42-L264 HydrophobicContact CD2-CD1 4.29Å; R260-L264 HydrophobicContact CG-CD1 3.65Å; R260-L264 WeakPolarHBondContact O-CB 3.48Å; R260-L264 WeakPolarHBondContact O-CD1 3.29Å; R260-L264 VanDerWaalsContact O-CG 3.22Å; R260-L264 WeakPolarHBondContact O-CG 3.49Å; R260-L264 PolarHBondContact O-N 3.02Å; L262-L264 PolarHBondContact O-N 3.29Å; L264-I266 VanDerWaalsContact C-N 3.3Å; L264-I266 PolarHBondContact O-N 3.37Å; L264-A267 PolarHBondContact O-N 3.13Å; L264-I268 WeakPolarHBondContact O-CB 3.31Å; L264-I268 VanDerWaalsContact O-CG1 3.31Å; L264-I268 WeakPolarHBondContact O-CG1 3.49Å; L264-I268 PolarHBondContact O-N 3.02Å
265	A	91.4	Very high	90.3	Very high	1 Å²	1	46.8 Å²	46.8	1%	0.008	24%	0.242	C	C	.	.	H	α-helix	trans	-59.7	-44.3	176.9	0	0	0	0	0	110.9	L42 I46 I49 L248 N261 L262 S269	L42-A265 HydrophobicContact CD1-CB 3.98Å; I46-A265 HydrophobicContact CG1-CB 4.17Å; I49-A265 HydrophobicContact CD1-CB 4.06Å; L248-A265 HydrophobicContact CD1-CB 3.65Å; N261-A265 WeakPolarHBondContact O-CB 3.38Å; N261-A265 PolarHBondContact O-N 3.05Å; L262-A265 PolarHBondContact O-N 3.43Å; A265-S269 WeakPolarHBondContact O-CB 3.49Å; A265-S269 PolarHBondContact O-N 3.06Å; A265-S269 PolarHBondContact O-OG 3.49Å
266	I	90.6	Very high	90.7	Very high	2 Å²	2	48 Å²	48	1%	0.01	25%	0.249	C	C	.	.	H	α-helix	trans	-64.9	-49.8	176.7	-71.6	169	0	0	0	111.3	I49 A90 A94 L262 P263 L264 I268 S269 M270	I49-I266 HydrophobicContact CD1-CB 4.47Å; I49-I266 HydrophobicContact CD1-CG1 3.68Å; A90-I266 HydrophobicContact CB-CG2 3.37Å; A94-I266 HydrophobicContact CB-CD1 3.93Å; L262-I266 HydrophobicContact CD1-CD1 4.2Å; L262-I266 HydrophobicContact CG-CD1 4.33Å; L262-I266 WeakPolarHBondContact O-CG1 3.31Å; L262-I266 PolarHBondContact O-N 3.41Å; P263-I266 PolarHBondContact O-N 2.79Å; L264-I266 VanDerWaalsContact C-N 3.3Å; L264-I266 PolarHBondContact O-N 3.37Å; I266-I268 PolarHBondContact O-N 3.47Å; I266-S269 PolarHBondContact O-N 3.31Å; I266-M270 HydrophobicContact CG2-CG 4.05Å; I266-M270 WeakPolarHBondContact O-CB 3.25Å; I266-M270 VanDerWaalsContact O-CG 3.28Å; I266-M270 WeakPolarHBondContact O-CG 3.46Å; I266-M270 PolarHBondContact O-N 2.97Å
267	A	89.3	Confident	91.2	Very high	54 Å²	54	44.2 Å²	44.2	45%	0.446	23%	0.231	S	C	.	.	H	α-helix	trans	-61.5	-31.2	-176.7	0	0	0	0	0	113.2	P263 L264 P271	P263-A267 VanDerWaalsContact O-CB 3.28Å; P263-A267 WeakPolarHBondContact O-CB 3.26Å; P263-A267 PolarHBondContact O-N 3.43Å; L264-A267 PolarHBondContact O-N 3.13Å; A267-P271 WeakPolarHBondContact O-CD 3.27Å; A267-P271 WeakPolarHBondContact O-CG 3Å
268	I	92.1	Very high	91.6	Very high	71 Å²	71	41.1 Å²	41.1	36%	0.364	21%	0.214	S	C	.	.	H	α-helix	trans	-83.7	-44.3	176.9	-65.5	166.6	0	0	0	111.1	I46 L264 I266 P271 I272	I46-I268 HydrophobicContact CD1-CB 4.27Å; I46-I268 HydrophobicContact CD1-CD1 3.87Å; I46-I268 HydrophobicContact CD1-CG2 4.05Å; I46-I268 HydrophobicContact CG1-CB 4.49Å; I46-I268 HydrophobicContact CG1-CG2 4.48Å; I46-I268 HydrophobicContact CG2-CG2 4.41Å; L264-I268 WeakPolarHBondContact O-CB 3.31Å; L264-I268 VanDerWaalsContact O-CG1 3.31Å; L264-I268 WeakPolarHBondContact O-CG1 3.49Å; L264-I268 PolarHBondContact O-N 3.02Å; I266-I268 PolarHBondContact O-N 3.47Å; I268-P271 WeakPolarHBondContact O-CD 3.28Å; I268-I272 HydrophobicContact CG2-CD1 3.68Å; I268-I272 VanDerWaalsContact O-CD1 3.32Å; I268-I272 WeakPolarHBondContact O-CD1 3.26Å; I268-I272 VanDerWaalsContact O-CG1 3.26Å; I268-I272 WeakPolarHBondContact O-CG1 3.4Å
269	S	91.8	Very high	92.1	Very high	0 Å²	0	43.8 Å²	43.8	0%	0	23%	0.227	C	C	.	.	H	α-helix	trans	-69.8	-40.2	-172.8	-55.4	0	0	0	0	112.6	I49 A265 I266 I272 V273	I49-S269 VanDerWaalsContact CG2-CB 3.43Å; A265-S269 WeakPolarHBondContact O-CB 3.49Å; A265-S269 PolarHBondContact O-N 3.06Å; A265-S269 PolarHBondContact O-OG 3.49Å; I266-S269 PolarHBondContact O-N 3.31Å; S269-I272 PolarHBondContact O-N 2.76Å; S269-V273 WeakPolarHBondContact O-CG2 3.27Å; S269-V273 PolarHBondContact O-N 2.77Å
270	M	91.8	Very high	92.4	Very high	2 Å²	2	38.5 Å²	38.5	1%	0.01	20%	0.202	C	C	.	.	H	α-helix	trans	-63.5	-46.8	-173.9	-66.8	-57.1	-56.3	0	0	113.9	M53 V87 A90 W245 I266 T274	M53-M270 HydrophobicContact CE-CE 3.6Å; M53-M270 HydrophobicContact CE-SD 3.59Å; M53-M270 VanDerWaalsContact CE-SD 3.59Å; M53-M270 HydrophobicContact SD-CE 4.45Å; M53-M270 HydrophobicContact SD-SD 3.63Å; M53-M270 VanDerWaalsContact SD-SD 3.63Å; V87-M270 HydrophobicContact CG2-CB 3.61Å; V87-M270 HydrophobicContact CG2-CE 4.35Å; V87-M270 HydrophobicContact CG2-CG 4.32Å; A90-M270 HydrophobicContact CB-CG 4.15Å; A90-M270 HydrophobicContact CB-SD 4.28Å; W245-M270 HydrophobicContact CB-SD 3.59Å; W245-M270 VanDerWaalsContact CB-SD 3.59Å; W245-M270 HydrophobicContact CG-SD 4.13Å; I266-M270 HydrophobicContact CG2-CG 4.05Å; I266-M270 WeakPolarHBondContact O-CB 3.25Å; I266-M270 VanDerWaalsContact O-CG 3.28Å; I266-M270 WeakPolarHBondContact O-CG 3.46Å; I266-M270 PolarHBondContact O-N 2.97Å; M270-T274 WeakPolarHBondContact O-CB 3.44Å; M270-T274 PolarHBondContact O-N 3.41Å; M270-T274 PolarHBondContact O-OG1 2.7Å
271	P	91.9	Very high	92.7	Very high	60 Å²	60	30.3 Å²	30.3	39%	0.39	17%	0.171	S	C	.	.	H	α-helix	trans	-63.2	-39.9	174.2	-24	35.4	0	0	0	112.9	A267 I268 V273 T274 I275	A267-P271 WeakPolarHBondContact O-CD 3.27Å; A267-P271 WeakPolarHBondContact O-CG 3Å; I268-P271 WeakPolarHBondContact O-CD 3.28Å; P271-V273 PolarHBondContact O-N 3.12Å; P271-T274 PolarHBondContact O-N 3.29Å; P271-I275 VanDerWaalsContact O-CG1 3.29Å; P271-I275 WeakPolarHBondContact O-CG1 3.29Å; P271-I275 PolarHBondContact O-N 3.38Å
272	I	92	Very high	93	Very high	68 Å²	68	31.1 Å²	31.1	35%	0.349	18%	0.177	S	C	.	.	H	α-helix	trans	-58.7	-51.4	178.9	-69.5	171.2	0	0	0	110.2	I268 S269 T274 I275 I276	I268-I272 HydrophobicContact CG2-CD1 3.68Å; I268-I272 VanDerWaalsContact O-CD1 3.32Å; I268-I272 WeakPolarHBondContact O-CD1 3.26Å; I268-I272 VanDerWaalsContact O-CG1 3.26Å; I268-I272 WeakPolarHBondContact O-CG1 3.4Å; S269-I272 PolarHBondContact O-N 2.76Å; I272-T274 VanDerWaalsContact C-N 3.32Å; I272-T274 PolarHBondContact O-N 2.98Å; I272-I275 PolarHBondContact O-N 3.2Å; I272-I276 HydrophobicContact CG2-CD1 3.72Å; I272-I276 VanDerWaalsContact O-CG1 3.29Å; I272-I276 WeakPolarHBondContact O-CG1 3.42Å; I272-I276 PolarHBondContact O-N 3.45Å
273	V	93.3	Very high	93.3	Very high	0 Å²	0	31.1 Å²	31.1	0%	0	18%	0.177	C	C	.	.	H	α-helix	trans	-62.1	-42.2	179.5	175.8	0	0	0	0	110.8	V50 M53 I54 Y242 S269 P271 I275 I276 Y277	V50-V273 HydrophobicContact CG1-CG2 4.43Å; V50-V273 HydrophobicContact CG2-CG2 4.23Å; M53-V273 HydrophobicContact CB-CG1 4.28Å; M53-V273 HydrophobicContact CB-CG2 4.29Å; M53-V273 HydrophobicContact CE-CB 4.26Å; M53-V273 HydrophobicContact CE-CG1 3.87Å; M53-V273 HydrophobicContact CE-CG2 4.47Å; M53-V273 HydrophobicContact SD-CB 4.44Å; M53-V273 HydrophobicContact SD-CG1 4.42Å; M53-V273 HydrophobicContact SD-CG2 4.03Å; I54-V273 HydrophobicContact CD1-CG2 4.23Å; I54-V273 HydrophobicContact CG1-CG1 4.25Å; I54-V273 HydrophobicContact CG1-CG2 4.05Å; Y242-V273 HydrophobicContact CD1-CG1 4.24Å; Y242-V273 HydrophobicContact CE1-CG1 4.18Å; S269-V273 WeakPolarHBondContact O-CG2 3.27Å; S269-V273 PolarHBondContact O-N 2.77Å; P271-V273 PolarHBondContact O-N 3.12Å; V273-I275 PolarHBondContact O-N 3.04Å; V273-I276 PolarHBondContact O-N 2.9Å; V273-Y277 HydrophobicContact CG1-CD1 4.27Å; V273-Y277 HydrophobicContact CG1-CD2 3.85Å; V273-Y277 HydrophobicContact CG1-CE1 3.93Å; V273-Y277 HydrophobicContact CG1-CE2 3.47Å; V273-Y277 VanDerWaalsContact CG1-CE2 3.47Å; V273-Y277 HydrophobicContact CG1-CG 4.26Å; V273-Y277 WeakPolarHBondContact O-CB 3.45Å; V273-Y277 PolarHBondContact O-N 3.3Å
274	T	94.4	Very high	93.5	Very high	20 Å²	20	30 Å²	30	12%	0.123	17%	0.17	C	C	.	.	H	α-helix	trans	-61.3	-45.2	179.2	-56.7	0	0	0	0	112.1	M270 P271 I272 Y277 L278	M270-T274 WeakPolarHBondContact O-CB 3.44Å; M270-T274 PolarHBondContact O-N 3.41Å; M270-T274 PolarHBondContact O-OG1 2.7Å; P271-T274 PolarHBondContact O-N 3.29Å; I272-T274 VanDerWaalsContact C-N 3.32Å; I272-T274 PolarHBondContact O-N 2.98Å; T274-Y277 PolarHBondContact O-N 3.04Å; T274-L278 HydrophobicContact CG2-CD1 4.16Å; T274-L278 WeakPolarHBondContact O-CG 3.22Å; T274-L278 PolarHBondContact O-N 2.81Å
275	I	94.6	Very high	93.7	Very high	100 Å²	100	26.9 Å²	26.9	51%	0.513	15%	0.153	S	C	.	.	H	α-helix	trans	-63.9	-45.9	177.2	-69	165.9	0	0	0	110.3	P271 I272 V273 Y277 L278 L279	P271-I275 VanDerWaalsContact O-CG1 3.29Å; P271-I275 WeakPolarHBondContact O-CG1 3.29Å; P271-I275 PolarHBondContact O-N 3.38Å; I272-I275 PolarHBondContact O-N 3.2Å; V273-I275 PolarHBondContact O-N 3.04Å; I275-Y277 VanDerWaalsContact C-N 3.33Å; I275-Y277 PolarHBondContact O-N 3.38Å; I275-L278 PolarHBondContact O-N 3.33Å; I275-L279 HydrophobicContact CG2-CD1 3.69Å; I275-L279 HydrophobicContact CG2-CG 4.19Å; I275-L279 WeakPolarHBondContact O-CB 3.31Å; I275-L279 VanDerWaalsContact O-CG 3.26Å; I275-L279 WeakPolarHBondContact O-CG 3.25Å; I275-L279 PolarHBondContact O-N 3.33Å
276	I	94.1	Very high	93.8	Very high	31 Å²	31	27.2 Å²	27.2	16%	0.159	16%	0.155	C	C	.	.	H	α-helix	trans	-59.2	-45.1	178.7	-71	169.5	0	0	0	110.7	I54 L198 I202 I272 V273 L279 T280	I54-I276 HydrophobicContact CD1-CD1 3.88Å; I54-I276 HydrophobicContact CD1-CG2 4.35Å; L198-I276 HydrophobicContact CB-CG2 4.38Å; L198-I276 HydrophobicContact CD1-CG2 3.97Å; I202-I276 HydrophobicContact CD1-CG2 4.25Å; I272-I276 HydrophobicContact CG2-CD1 3.72Å; I272-I276 VanDerWaalsContact O-CG1 3.29Å; I272-I276 WeakPolarHBondContact O-CG1 3.42Å; I272-I276 PolarHBondContact O-N 3.45Å; V273-I276 PolarHBondContact O-N 2.9Å; I276-L279 PolarHBondContact O-N 3.01Å; I276-T280 VanDerWaalsContact O-CB 3.28Å; I276-T280 WeakPolarHBondContact O-CB 3.5Å; I276-T280 PolarHBondContact O-N 2.92Å; I276-T280 PolarHBondContact O-OG1 3.32Å
277	Y	95.3	Very high	93.8	Very high	0 Å²	0	27.9 Å²	27.9	0%	0	16%	0.161	C	C	.	.	H	α-helix	trans	-66	-43.4	180	-71.6	-4	0	0	0	112.6	M53 I54 I58 W79 S241 Y242 V273 T274 I275 T280 N281	M53-Y277 VanDerWaalsContact C-OH 3.29Å; M53-Y277 PolarHBondContact O-OH 3.2Å; I54-Y277 WeakPolarHBondContact CA-OH 3.29Å; I54-Y277 HydrophobicContact CG1-CE1 4.06Å; I58-Y277 HydrophobicContact CB-CD1 4.11Å; I58-Y277 HydrophobicContact CB-CE1 3.74Å; I58-Y277 HydrophobicContact CD1-CD1 3.58Å; I58-Y277 HydrophobicContact CD1-CE1 4.11Å; I58-Y277 HydrophobicContact CD1-CG 3.83Å; I58-Y277 HydrophobicContact CG1-CD1 3.73Å; I58-Y277 HydrophobicContact CG1-CE1 3.89Å; I58-Y277 HydrophobicContact CG1-CG 4.47Å; I58-Y277 HydrophobicContact CG2-CE1 4.36Å; W79-Y277 AromaticContact CE3-CD2 3.95Å; W79-Y277 HydrophobicContact CE3-CD2 3.95Å; W79-Y277 HydrophobicContact CE3-CG 4.27Å; W79-Y277 HydrophobicContact CH2-CD2 4.47Å; W79-Y277 AromaticContact CZ3-CD2 3.43Å; W79-Y277 HydrophobicContact CZ3-CD2 3.43Å; W79-Y277 VanDerWaalsContact CZ3-CD2 3.43Å; W79-Y277 HydrophobicContact CZ3-CE2 4.09Å; W79-Y277 AromaticContact CZ3-CG 3.85Å; W79-Y277 HydrophobicContact CZ3-CG 3.85Å; S241-Y277 VanDerWaalsContact O-CE2 3.23Å; S241-Y277 WeakPolarHBondContact O-CE2 3.23Å; S241-Y277 PolarHBondContact O-OH 2.92Å; Y242-Y277 AromaticContact CD1-CD2 3.99Å; Y242-Y277 HydrophobicContact CD1-CD2 3.99Å; Y242-Y277 AromaticContact CD1-CE2 3.94Å; Y242-Y277 HydrophobicContact CD1-CE2 3.94Å; Y242-Y277 HydrophobicContact CD2-CD2 4.39Å; Y242-Y277 AromaticContact CE1-CD2 3.54Å; Y242-Y277 HydrophobicContact CE1-CD2 3.54Å; Y242-Y277 AromaticContact CE1-CE2 3.96Å; Y242-Y277 HydrophobicContact CE1-CE2 3.96Å; Y242-Y277 AromaticContact CE2-CD2 3.98Å; Y242-Y277 HydrophobicContact CE2-CD2 3.98Å; Y242-Y277 HydrophobicContact CG-CD2 4.39Å; Y242-Y277 HydrophobicContact CG-CE2 4.24Å; Y242-Y277 AromaticContact CZ-CD2 3.52Å; V273-Y277 HydrophobicContact CG1-CD1 4.27Å; V273-Y277 HydrophobicContact CG1-CD2 3.85Å; V273-Y277 HydrophobicContact CG1-CE1 3.93Å; V273-Y277 HydrophobicContact CG1-CE2 3.47Å; V273-Y277 VanDerWaalsContact CG1-CE2 3.47Å; V273-Y277 HydrophobicContact CG1-CG 4.26Å; V273-Y277 WeakPolarHBondContact O-CB 3.45Å; V273-Y277 PolarHBondContact O-N 3.3Å; T274-Y277 PolarHBondContact O-N 3.04Å; I275-Y277 VanDerWaalsContact C-N 3.33Å; I275-Y277 PolarHBondContact O-N 3.38Å; Y277-T280 PolarHBondContact O-N 2.89Å; Y277-N281 PolarHBondContact O-N 2.86Å; Y277-N281 PolarHBondContact O-ND2 2.66Å
278	L	96.3	Very high	94	Very high	46 Å²	46	25.7 Å²	25.7	24%	0.241	14%	0.142	C	C	.	.	H	α-helix	trans	-61.9	-48	175.4	-73.7	171.5	0	0	0	111.4	L76 W79 A80 T274 I275 T280 N281 V282	L76-L278 HydrophobicContact CD2-CD2 4.32Å; L76-L278 WeakPolarHBondContact O-CD2 3.42Å; W79-L278 HydrophobicContact CB-CD2 3.72Å; A80-L278 HydrophobicContact CB-CD1 4.35Å; A80-L278 HydrophobicContact CB-CD2 4.3Å; T274-L278 HydrophobicContact CG2-CD1 4.16Å; T274-L278 WeakPolarHBondContact O-CG 3.22Å; T274-L278 PolarHBondContact O-N 2.81Å; I275-L278 PolarHBondContact O-N 3.33Å; L278-T280 VanDerWaalsContact C-N 3.3Å; L278-T280 PolarHBondContact O-N 3.44Å; L278-N281 PolarHBondContact O-N 3.38Å; L278-V282 VanDerWaalsContact O-CG2 3.31Å; L278-V282 WeakPolarHBondContact O-CG2 3.38Å; L278-V282 PolarHBondContact O-N 3.43Å
279	L	96.2	Very high	93.9	Very high	72 Å²	72	25.2 Å²	25.2	38%	0.377	14%	0.14	S	C	.	.	H	α-helix	trans	-63.6	-36.3	178.8	-68.8	177.3	0	0	0	112.5	I202 I275 I276 V282 A283	I202-L279 HydrophobicContact CD1-CB 3.92Å; I202-L279 HydrophobicContact CD1-CD1 4.46Å; I202-L279 HydrophobicContact CG1-CB 3.84Å; I202-L279 HydrophobicContact CG2-CB 4.04Å; I202-L279 HydrophobicContact CG2-CD1 4.06Å; I275-L279 HydrophobicContact CG2-CD1 3.69Å; I275-L279 HydrophobicContact CG2-CG 4.19Å; I275-L279 WeakPolarHBondContact O-CB 3.31Å; I275-L279 VanDerWaalsContact O-CG 3.26Å; I275-L279 WeakPolarHBondContact O-CG 3.25Å; I275-L279 PolarHBondContact O-N 3.33Å; I276-L279 PolarHBondContact O-N 3.01Å; L279-V282 PolarHBondContact O-N 3.13Å; L279-A283 WeakPolarHBondContact O-CB 3.44Å; L279-A283 PolarHBondContact O-N 2.98Å
280	T	95.3	Very high	93.9	Very high	0 Å²	0	28 Å²	28	0%	0	15%	0.154	C	C	.	.	H	α-helix	trans	-66.2	-44.9	176.6	-57.5	0	0	0	0	111.1	I58 L198 I201 I276 Y277 L278 A283 Y284	I58-T280 HydrophobicContact CD1-CG2 4.38Å; I58-T280 HydrophobicContact CG1-CG2 4.05Å; L198-T280 HydrophobicContact CD2-CG2 4.01Å; I201-T280 HydrophobicContact CG2-CG2 4.09Å; I276-T280 VanDerWaalsContact O-CB 3.28Å; I276-T280 WeakPolarHBondContact O-CB 3.5Å; I276-T280 PolarHBondContact O-N 2.92Å; I276-T280 PolarHBondContact O-OG1 3.32Å; Y277-T280 PolarHBondContact O-N 2.89Å; L278-T280 VanDerWaalsContact C-N 3.3Å; L278-T280 PolarHBondContact O-N 3.44Å; T280-A283 WeakPolarHBondContact O-CB 3.01Å; T280-A283 PolarHBondContact O-N 3Å; T280-Y284 HydrophobicContact CG2-CD2 4.26Å; T280-Y284 HydrophobicContact CG2-CE1 4.42Å; T280-Y284 HydrophobicContact CG2-CE2 3.64Å; T280-Y284 PolarHBondContact O-N 3.33Å
281	N	96.3	Very high	93.9	Very high	0 Å²	0	32 Å²	32	0%	0	18%	0.182	C	C	.	.	H	α-helix	trans	-65.5	-40.7	176.2	-78.7	-80.5	0	0	0	112	P62 L76 W79 Y277 L278 A283 Y284 Y285	P62-N281 WeakPolarHBondContact CB-OD1 3.49Å; L76-N281 HydrophobicContact CD2-CB 3.83Å; W79-N281 WeakPolarHBondContact CZ2-ND2 3.44Å; W79-N281 PolarHBondContact NE1-ND2 3.24Å; W79-N281 PolarHBondContact NE1-OD1 2.85Å; Y277-N281 PolarHBondContact O-N 2.86Å; Y277-N281 PolarHBondContact O-ND2 2.66Å; L278-N281 PolarHBondContact O-N 3.38Å; N281-A283 VanDerWaalsContact C-N 3.31Å; N281-A283 PolarHBondContact O-N 2.93Å; N281-Y284 PolarHBondContact O-N 3.33Å; N281-Y285 HydrophobicContact CB-CE2 4.11Å; N281-Y285 WeakPolarHBondContact O-CD2 3.46Å; N281-Y285 PolarHBondContact O-N 3.5Å; N281-Y285 PolarHBondContact OD1-OH 2.9Å
282	V	95.8	Very high	93.9	Very high	36 Å²	36	31.3 Å²	31.3	22%	0.218	18%	0.179	C	C	.	.	H	α-helix	trans	-57.2	-46.8	172	170	0	0	0	0	110.2	L76 I209 F217 L278 L279 Y284 Y285 V286	L76-V282 HydrophobicContact CD1-CG2 3.95Å; L76-V282 HydrophobicContact CD2-CG2 3.91Å; I209-V282 HydrophobicContact CD1-CG1 3.83Å; F217-V282 HydrophobicContact CZ-CG1 4.39Å; L278-V282 VanDerWaalsContact O-CG2 3.31Å; L278-V282 WeakPolarHBondContact O-CG2 3.38Å; L278-V282 PolarHBondContact O-N 3.43Å; L279-V282 PolarHBondContact O-N 3.13Å; V282-Y284 VanDerWaalsContact C-N 3.33Å; V282-Y284 PolarHBondContact O-N 3.14Å; V282-Y285 PolarHBondContact O-N 2.96Å; V282-V286 HydrophobicContact CG1-CG2 4.24Å; V282-V286 VanDerWaalsContact O-CG2 3.24Å; V282-V286 WeakPolarHBondContact O-CG2 3.13Å; V282-V286 PolarHBondContact O-N 3.44Å
283	A	95.4	Very high	93.9	Very high	1 Å²	1	28.1 Å²	28.1	1%	0.008	16%	0.162	C	C	.	.	H	α-helix	trans	-59.3	-41.8	177.2	0	0	0	0	0	112.6	I201 L279 T280 N281 A287 F303	I201-A283 HydrophobicContact CG2-CB 3.73Å; I201-A283 WeakPolarHBondContact O-CB 3.25Å; L279-A283 WeakPolarHBondContact O-CB 3.44Å; L279-A283 PolarHBondContact O-N 2.98Å; T280-A283 WeakPolarHBondContact O-CB 3.01Å; T280-A283 PolarHBondContact O-N 3Å; N281-A283 VanDerWaalsContact C-N 3.31Å; N281-A283 PolarHBondContact O-N 2.93Å; A283-A287 WeakPolarHBondContact O-CB 3.23Å; A283-A287 PolarHBondContact O-N 3.22Å; A283-F303 HydrophobicContact CB-CE2 4.39Å; A283-F303 WeakPolarHBondContact O-CE2 3.17Å
284	Y	94.8	Very high	93.8	Very high	0 Å²	0	30.5 Å²	30.5	0%	0	18%	0.175	C	C	.	.	H	α-helix	trans	-61.7	-46.5	174.6	-66.8	-29.6	0	0	0	112.3	P62 I201 T280 N281 V282 V286 A287 L288 V299 A300 F303	P62-Y284 HydrophobicContact CB-CD2 4.18Å; P62-Y284 HydrophobicContact CB-CE2 4.47Å; P62-Y284 HydrophobicContact CG-CD2 4.08Å; P62-Y284 HydrophobicContact CG-CE2 3.93Å; I201-Y284 HydrophobicContact CD1-CE1 4.2Å; I201-Y284 HydrophobicContact CG2-CD1 4.27Å; I201-Y284 HydrophobicContact CG2-CE1 3.85Å; T280-Y284 HydrophobicContact CG2-CD2 4.26Å; T280-Y284 HydrophobicContact CG2-CE1 4.42Å; T280-Y284 HydrophobicContact CG2-CE2 3.64Å; T280-Y284 PolarHBondContact O-N 3.33Å; N281-Y284 PolarHBondContact O-N 3.33Å; V282-Y284 VanDerWaalsContact C-N 3.33Å; V282-Y284 PolarHBondContact O-N 3.14Å; Y284-V286 VanDerWaalsContact C-N 3.34Å; Y284-V286 PolarHBondContact O-N 2.93Å; Y284-A287 PolarHBondContact O-N 3.4Å; Y284-L288 WeakPolarHBondContact O-CB 3.19Å; Y284-L288 PolarHBondContact O-N 3.37Å; Y284-V299 HydrophobicContact CD1-CG1 4.23Å; Y284-V299 HydrophobicContact CD2-CG1 3.91Å; Y284-V299 HydrophobicContact CE1-CG1 4.42Å; Y284-V299 HydrophobicContact CE2-CG1 4.09Å; Y284-V299 HydrophobicContact CG-CG1 3.99Å; Y284-A300 HydrophobicContact CE1-CB 4.28Å; Y284-A300 VanDerWaalsContact OH-CB 3.26Å; Y284-A300 WeakPolarHBondContact OH-CB 3.49Å; Y284-F303 HydrophobicContact CD1-CB 3.96Å; Y284-F303 AromaticContact CD1-CD2 3.76Å; Y284-F303 HydrophobicContact CD1-CD2 3.76Å; Y284-F303 HydrophobicContact CD1-CE2 4.48Å; Y284-F303 AromaticContact CD1-CG 3.95Å; Y284-F303 HydrophobicContact CD1-CG 3.95Å; Y284-F303 HydrophobicContact CE1-CB 3.96Å; Y284-F303 HydrophobicContact CE1-CD2 4.29Å; Y284-F303 HydrophobicContact CE1-CG 4.04Å
285	Y	94.6	Very high	93.6	Very high	0 Å²	0	33.2 Å²	33.2	0%	0	20%	0.199	C	C	.	.	H	α-helix	trans	-72.4	-25.1	-177.5	-57.3	-22	0	0	0	113.5	L66 Y72 S75 L76 N216 F217 N281 V282 L293	L66-Y285 HydrophobicContact CD1-CE1 4.44Å; L66-Y285 HydrophobicContact CD2-CE1 4.12Å; Y72-Y285 AromaticContact CD1-CD1 3.56Å; Y72-Y285 HydrophobicContact CD1-CD1 3.56Å; Y72-Y285 AromaticContact CD1-CD2 3.84Å; Y72-Y285 HydrophobicContact CD1-CD2 3.84Å; Y72-Y285 AromaticContact CD1-CE1 4Å; Y72-Y285 HydrophobicContact CD1-CE1 4Å; Y72-Y285 HydrophobicContact CD1-CE2 4.22Å; Y72-Y285 AromaticContact CD1-CG 3.5Å; Y72-Y285 HydrophobicContact CD1-CG 3.5Å; Y72-Y285 AromaticContact CE1-CD1 3.8Å; Y72-Y285 HydrophobicContact CE1-CD1 3.8Å; Y72-Y285 HydrophobicContact CE1-CE1 4.39Å; Y72-Y285 HydrophobicContact CE1-CG 4.05Å; Y72-Y285 HydrophobicContact CG-CD2 4.18Å; Y72-Y285 HydrophobicContact CG-CG 4.11Å; S75-Y285 WeakPolarHBondContact CB-OH 3.4Å; S75-Y285 PolarHBondContact OG-OH 2.92Å; L76-Y285 HydrophobicContact CD2-CD2 4.29Å; L76-Y285 HydrophobicContact CD2-CE2 3.96Å; L76-Y285 HydrophobicContact CG-CD2 4.27Å; L76-Y285 HydrophobicContact CG-CE2 4.01Å; N216-Y285 VanDerWaalsContact CB-O 3.29Å; N216-Y285 WeakPolarHBondContact CB-O 3.38Å; N216-Y285 PolarHBondContact ND2-O 3.19Å; F217-Y285 HydrophobicContact CZ-CD2 4.35Å; N281-Y285 HydrophobicContact CB-CE2 4.11Å; N281-Y285 WeakPolarHBondContact O-CD2 3.46Å; N281-Y285 PolarHBondContact O-N 3.5Å; N281-Y285 PolarHBondContact OD1-OH 2.9Å; V282-Y285 PolarHBondContact O-N 2.96Å; Y285-L293 HydrophobicContact CD1-CD1 3.68Å; Y285-L293 HydrophobicContact CE1-CD1 3.57Å
286	V	93.8	Very high	93.3	Very high	8 Å²	8	28.9 Å²	28.9	5%	0.048	18%	0.178	C	C	.	.	H	α-helix	trans	-71.8	-36.6	170.8	173.8	0	0	0	0	111.1	K208 I209 E213 F217 V282 Y284	K208-V286 HydrophobicContact CB-CG1 3.42Å; K208-V286 VanDerWaalsContact CB-CG1 3.42Å; K208-V286 HydrophobicContact CD-CG1 4.16Å; K208-V286 HydrophobicContact CG-CG1 4.43Å; I209-V286 HydrophobicContact CD1-CG2 3.91Å; I209-V286 HydrophobicContact CG1-CG1 4.18Å; I209-V286 HydrophobicContact CG1-CG2 3.58Å; E213-V286 WeakPolarHBondContact O-CG1 3.24Å; F217-V286 HydrophobicContact CD2-CG2 4.2Å; F217-V286 HydrophobicContact CE2-CB 4.5Å; F217-V286 HydrophobicContact CE2-CG2 3.51Å; F217-V286 HydrophobicContact CZ-CG2 4.44Å; V282-V286 HydrophobicContact CG1-CG2 4.24Å; V282-V286 VanDerWaalsContact O-CG2 3.24Å; V282-V286 WeakPolarHBondContact O-CG2 3.13Å; V282-V286 PolarHBondContact O-N 3.44Å; Y284-V286 VanDerWaalsContact C-N 3.34Å; Y284-V286 PolarHBondContact O-N 2.93Å
287	A	91.5	Very high	92.9	Very high	17 Å²	17	30.8 Å²	30.8	14%	0.14	19%	0.188	C	C	.	.	H	α-helix	trans	-92.9	-27.5	-171.5	0	0	0	0	0	114.6	K208 A283 Y284 F303 V307	K208-A287 HydrophobicContact CD-CB 3.97Å; A283-A287 WeakPolarHBondContact O-CB 3.23Å; A283-A287 PolarHBondContact O-N 3.22Å; Y284-A287 PolarHBondContact O-N 3.4Å; A287-F303 HydrophobicContact CB-CD2 3.47Å; A287-F303 VanDerWaalsContact CB-CD2 3.47Å; A287-F303 HydrophobicContact CB-CE2 3.4Å; A287-F303 VanDerWaalsContact CB-CE2 3.4Å; A287-V307 HydrophobicContact CB-CG2 3.95Å
288	L	92	Very high	92.6	Very high	8 Å²	8	30.8 Å²	30.8	4%	0.042	19%	0.188	C	C	.	.	S	Bend	trans	-122.7	140.6	-174.3	-57.9	176.9	0	0	0	110.5	N216 Y284 V299 T302 F303 A306	N216-L288 PolarHBondContact ND2-O 3.33Å; Y284-L288 WeakPolarHBondContact O-CB 3.19Å; Y284-L288 PolarHBondContact O-N 3.37Å; L288-V299 HydrophobicContact CD1-CG1 4.23Å; L288-T302 HydrophobicContact CD1-CG2 4.26Å; L288-T302 HydrophobicContact CD2-CG2 3.99Å; L288-F303 HydrophobicContact CD1-CB 4.23Å; L288-A306 HydrophobicContact CD2-CB 3.96Å
289	D	91.8	Very high	92.3	Very high	61 Å²	61	28.7 Å²	28.7	33%	0.326	18%	0.177	S	C	.	.			trans	-76.5	164.9	167.4	64.9	-74.6	0	0	0	111.8	S291 S292 L293	D289-S291 PolarHBondContact O-N 3.29Å; D289-S291 WeakPolarHBondContact OD2-CB 3.5Å; D289-S291 PolarHBondContact OD2-N 2.99Å; D289-S291 PolarHBondContact OD2-OG 3.4Å; D289-S292 VanDerWaalsContact CG-OG 3.25Å; D289-S292 PolarHBondContact O-N 2.99Å; D289-S292 WeakPolarHBondContact OD1-CB 3.26Å; D289-S292 PolarHBondContact OD1-OG 3.48Å; D289-S292 PolarHBondContact OD2-N 3.42Å; D289-S292 PolarHBondContact OD2-OG 2.9Å; D289-L293 PolarHBondContact O-N 2.98Å
290	M	91.6	Very high	92.1	Very high	57 Å²	57	25.2 Å²	25.2	28%	0.281	16%	0.159	S	C	.	.	H	α-helix	trans	-65.7	-41.8	-170.4	-168.6	175.8	-159.4	0	0	111.1	L66 G70 Y72 L293 L294	L66-M290 HydrophobicContact CD1-CE 3.88Å; L66-M290 HydrophobicContact CD2-CE 4.4Å; L66-M290 HydrophobicContact CD2-CG 3.97Å; L66-M290 HydrophobicContact CG-CE 3.83Å; L66-M290 HydrophobicContact CG-CG 4.4Å; G70-M290 VanDerWaalsContact C-CE 3.44Å; G70-M290 WeakPolarHBondContact O-CE 3.45Å; Y72-M290 HydrophobicContact CE1-CB 4.29Å; Y72-M290 WeakPolarHBondContact OH-CA 3.49Å; Y72-M290 WeakPolarHBondContact OH-CB 3.28Å; Y72-M290 PolarHBondContact OH-N 3.44Å; M290-L293 PolarHBondContact O-N 2.7Å; M290-L294 HydrophobicContact CE-CD1 4.34Å; M290-L294 HydrophobicContact CG-CD1 3.92Å; M290-L294 HydrophobicContact CG-CG 4.36Å; M290-L294 WeakPolarHBondContact O-CB 3.3Å; M290-L294 VanDerWaalsContact O-CG 3.25Å; M290-L294 WeakPolarHBondContact O-CG 3.26Å; M290-L294 PolarHBondContact O-N 2.88Å
291	S	91.2	Very high	91.8	Very high	86 Å²	86	25.3 Å²	25.3	60%	0.601	16%	0.16	S	C	*	.	H	α-helix	trans	-61.7	-47.1	176.6	25.7	0	0	0	0	111.8	D289 L293 L294 A295	D289-S291 PolarHBondContact O-N 3.29Å; D289-S291 WeakPolarHBondContact OD2-CB 3.5Å; D289-S291 PolarHBondContact OD2-N 2.99Å; D289-S291 PolarHBondContact OD2-OG 3.4Å; S291-L293 VanDerWaalsContact C-N 3.34Å; S291-L293 PolarHBondContact O-N 3.01Å; S291-L294 PolarHBondContact O-N 3.49Å; S291-A295 VanDerWaalsContact O-CB 3.22Å; S291-A295 WeakPolarHBondContact O-CB 3.26Å; S291-A295 PolarHBondContact O-N 3.06Å
292	S	90.9	Very high	91.5	Very high	47 Å²	47	26.8 Å²	26.8	33%	0.329	17%	0.169	S	C	.	.	H	α-helix	trans	-63.1	-39.6	178.2	-64.3	0	0	0	0	112.5	D289 S296	D289-S292 VanDerWaalsContact CG-OG 3.25Å; D289-S292 PolarHBondContact O-N 2.99Å; D289-S292 WeakPolarHBondContact OD1-CB 3.26Å; D289-S292 PolarHBondContact OD1-OG 3.48Å; D289-S292 PolarHBondContact OD2-N 3.42Å; D289-S292 PolarHBondContact OD2-OG 2.9Å; S292-S296 WeakPolarHBondContact O-CB 3.46Å; S292-S296 PolarHBondContact O-N 3.44Å
293	L	92.1	Very high	91.3	Very high	0 Å²	0	25.1 Å²	25.1	0%	0	16%	0.158	C	C	.	.	H	α-helix	trans	-68.5	-43.3	178.6	-165.2	157.5	0	0	0	111.7	K63 L66 Y285 D289 M290 S291 S296 V299	K63-L293 HydrophobicContact CB-CD2 4.43Å; L66-L293 HydrophobicContact CB-CD2 4.35Å; L66-L293 HydrophobicContact CD2-CB 4.28Å; L66-L293 HydrophobicContact CD2-CD1 4.02Å; L66-L293 HydrophobicContact CD2-CD2 3.75Å; L66-L293 HydrophobicContact CD2-CG 4.22Å; Y285-L293 HydrophobicContact CD1-CD1 3.68Å; Y285-L293 HydrophobicContact CE1-CD1 3.57Å; D289-L293 PolarHBondContact O-N 2.98Å; M290-L293 PolarHBondContact O-N 2.7Å; S291-L293 VanDerWaalsContact C-N 3.34Å; S291-L293 PolarHBondContact O-N 3.01Å; L293-S296 PolarHBondContact O-N 3.38Å; L293-V299 HydrophobicContact CD1-CG1 4.3Å; L293-V299 HydrophobicContact CD2-CG2 4.22Å; L293-V299 HydrophobicContact CG-CG1 4Å; L293-V299 HydrophobicContact CG-CG2 4.38Å
294	L	92.6	Very high	91	Very high	51 Å²	51	25 Å²	25	27%	0.267	16%	0.158	S	C	.	.	H	α-helix	trans	-71.6	-29.5	179.1	-67.1	177.9	0	0	0	113.1	K63 L66 M67 M290 S291	K63-L294 WeakPolarHBondContact CE-O 3.22Å; K63-L294 PolarHBondContact NZ-O 2.97Å; L66-L294 HydrophobicContact CB-CD2 4.19Å; L66-L294 HydrophobicContact CD2-CD2 4.39Å; L66-L294 HydrophobicContact CD2-CG 4.49Å; L66-L294 HydrophobicContact CG-CD2 4.3Å; M67-L294 HydrophobicContact CB-CD2 3.83Å; M290-L294 HydrophobicContact CE-CD1 4.34Å; M290-L294 HydrophobicContact CG-CD1 3.92Å; M290-L294 HydrophobicContact CG-CG 4.36Å; M290-L294 WeakPolarHBondContact O-CB 3.3Å; M290-L294 VanDerWaalsContact O-CG 3.25Å; M290-L294 WeakPolarHBondContact O-CG 3.26Å; M290-L294 PolarHBondContact O-N 2.88Å; S291-L294 PolarHBondContact O-N 3.49Å
295	A	90.1	Very high	90.7	Very high	76 Å²	76	28 Å²	28	63%	0.628	17%	0.174	S	C	*	.	H	α-helix	trans	-77.2	-22.6	176.3	0	0	0	0	0	113.3	S291	S291-A295 VanDerWaalsContact O-CB 3.22Å; S291-A295 WeakPolarHBondContact O-CB 3.26Å; S291-A295 PolarHBondContact O-N 3.06Å
296	S	88.6	Confident	90.4	Very high	9 Å²	9	30.9 Å²	30.9	6%	0.063	20%	0.198	C	C	.	.			trans	-77.5	137.7	-178	176.3	0	0	0	0	112.1	K63 S292 L293 A298 V299 T302	K63-S296 VanDerWaalsContact CD-O 3.26Å; K63-S296 WeakPolarHBondContact CD-O 3.4Å; K63-S296 WeakPolarHBondContact CE-O 3.35Å; K63-S296 PolarHBondContact NZ-O 3.38Å; S292-S296 WeakPolarHBondContact O-CB 3.46Å; S292-S296 PolarHBondContact O-N 3.44Å; L293-S296 PolarHBondContact O-N 3.38Å; S296-A298 PolarHBondContact OG-N 3.44Å; S296-A298 PolarHBondContact OG-O 3.3Å; S296-V299 WeakPolarHBondContact OG-CA 3.3Å; S296-V299 PolarHBondContact OG-N 2.96Å; S296-T302 VanDerWaalsContact CB-OG1 3.28Å; S296-T302 WeakPolarHBondContact CB-OG1 3.42Å; S296-T302 PolarHBondContact OG-OG1 2.87Å
297	D	84.6	Confident	90.2	Very high	71 Å²	71	32.7 Å²	32.7	38%	0.38	21%	0.209	S	C	.	.	S	Bend	trans	-94.7	-19.2	169.3	-68.6	-41.7	0	0	0	112.3	K63	K63-D297 IonicContact NZ-OD1 2.67Å; K63-D297 PolarHBondContact NZ-OD1 3.08Å
298	A	89.4	Confident	89.8	Confident	0 Å²	0	33 Å²	33	0%	0	21%	0.208	C	C	.	.	S	Bend	trans	-124.9	80.7	170.8	0	0	0	0	0	111.8	Y145 E148 S296 A300 V301 T302	Y145-A298 HydrophobicContact CD1-CB 3.95Å; Y145-A298 HydrophobicContact CD2-CB 3.74Å; Y145-A298 HydrophobicContact CE1-CB 3.76Å; Y145-A298 HydrophobicContact CE2-CB 3.55Å; Y145-A298 HydrophobicContact CG-CB 3.94Å; E148-A298 HydrophobicContact CB-CB 4.45Å; E148-A298 HydrophobicContact CG-CB 4.49Å; E148-A298 WeakPolarHBondContact OE2-CB 3.26Å; E148-A298 PolarHBondContact OE2-N 3.2Å; E148-A298 VanDerWaalsContact OE2-N 3.09Å; S296-A298 PolarHBondContact OG-N 3.44Å; S296-A298 PolarHBondContact OG-O 3.3Å; A298-A300 PolarHBondContact O-N 3.43Å; A298-V301 HydrophobicContact CB-CB 4Å; A298-V301 HydrophobicContact CB-CG2 3.86Å; A298-V301 WeakPolarHBondContact O-CA 3.22Å; A298-V301 WeakPolarHBondContact O-CB 3.34Å; A298-V301 PolarHBondContact O-N 3.47Å; A298-T302 PolarHBondContact O-N 3.11Å; A298-T302 VanDerWaalsContact O-N 3.12Å; A298-T302 PolarHBondContact O-OG1 2.9Å
299	V	91	Very high	89.5	Confident	2 Å²	2	34.6 Å²	34.6	1%	0.012	23%	0.227	C	C	.	.	H	α-helix	trans	-51.3	-39.2	-173.6	178.7	0	0	0	0	112.8	K63 Y145 Y284 L288 L293 S296 T302 F303	K63-V299 HydrophobicContact CB-CG2 4.24Å; Y145-V299 PolarHBondContact OH-N 3.43Å; Y284-V299 HydrophobicContact CD1-CG1 4.23Å; Y284-V299 HydrophobicContact CD2-CG1 3.91Å; Y284-V299 HydrophobicContact CE1-CG1 4.42Å; Y284-V299 HydrophobicContact CE2-CG1 4.09Å; Y284-V299 HydrophobicContact CG-CG1 3.99Å; L288-V299 HydrophobicContact CD1-CG1 4.23Å; L293-V299 HydrophobicContact CD1-CG1 4.3Å; L293-V299 HydrophobicContact CD2-CG2 4.22Å; L293-V299 HydrophobicContact CG-CG1 4Å; L293-V299 HydrophobicContact CG-CG2 4.38Å; S296-V299 WeakPolarHBondContact OG-CA 3.3Å; S296-V299 PolarHBondContact OG-N 2.96Å; V299-T302 PolarHBondContact O-N 3.33Å; V299-F303 WeakPolarHBondContact O-CB 3.14Å; V299-F303 PolarHBondContact O-N 3.26Å
300	A	90.5	Very high	89.1	Confident	0 Å²	0	35.8 Å²	35.8	0%	0	24%	0.238	C	C	.	.	H	α-helix	trans	-71.9	-32	-179.7	0	0	0	0	0	112.9	F59 Y145 I201 Y284 A298 F303 G304 I315 V319	F59-A300 HydrophobicContact CD1-CB 3.84Å; F59-A300 HydrophobicContact CE1-CB 4.18Å; Y145-A300 HydrophobicContact CE1-CB 3.84Å; Y145-A300 PolarHBondContact OH-N 2.91Å; I201-A300 HydrophobicContact CD1-CB 4.34Å; Y284-A300 HydrophobicContact CE1-CB 4.28Å; Y284-A300 VanDerWaalsContact OH-CB 3.26Å; Y284-A300 WeakPolarHBondContact OH-CB 3.49Å; A298-A300 PolarHBondContact O-N 3.43Å; A300-F303 WeakPolarHBondContact O-CB 3.28Å; A300-F303 PolarHBondContact O-N 2.83Å; A300-G304 PolarHBondContact O-N 3.23Å; A300-I315 HydrophobicContact CB-CG2 3.63Å; A300-I315 VanDerWaalsContact O-CG2 3.32Å; A300-I315 WeakPolarHBondContact O-CG2 3.3Å; A300-V319 HydrophobicContact CB-CG2 4.41Å
301	V	89.6	Confident	88.6	Confident	2 Å²	2	39.1 Å²	39.1	1%	0.012	25%	0.251	C	S	.	.	H	α-helix	trans	-67.8	-43.4	173.9	177.1	0	0	0	0	109.6	Y145 E148 A298 F303 G304 N305 P316	Y145-V301 HydrophobicContact CD1-CG2 3.52Å; Y145-V301 HydrophobicContact CE1-CG2 3.8Å; Y145-V301 HydrophobicContact CG-CG2 4.41Å; E148-V301 HydrophobicContact CG-CG1 4.4Å; A298-V301 HydrophobicContact CB-CB 4Å; A298-V301 HydrophobicContact CB-CG2 3.86Å; A298-V301 WeakPolarHBondContact O-CA 3.22Å; A298-V301 WeakPolarHBondContact O-CB 3.34Å; A298-V301 PolarHBondContact O-N 3.47Å; V301-F303 VanDerWaalsContact C-N 3.34Å; V301-F303 PolarHBondContact O-N 3.08Å; V301-G304 PolarHBondContact O-N 3.41Å; V301-G304 VanDerWaalsContact O-N 3.12Å; V301-N305 WeakPolarHBondContact O-CB 3.2Å; V301-N305 VanDerWaalsContact O-CG 3.27Å; V301-N305 PolarHBondContact O-N 2.87Å; V301-N305 PolarHBondContact O-ND2 3.15Å; V301-P316 HydrophobicContact CG2-CB 3.88Å; V301-P316 HydrophobicContact CG2-CG 4.45Å
302	T	90.4	Very high	88.2	Confident	31 Å²	31	39 Å²	39	19%	0.19	24%	0.239	C	C	.	.	H	α-helix	trans	-60.4	-43.2	174.7	-48.1	0	0	0	0	111.7	L288 S296 A298 V299 G304 N305 A306	L288-T302 HydrophobicContact CD1-CG2 4.26Å; L288-T302 HydrophobicContact CD2-CG2 3.99Å; S296-T302 VanDerWaalsContact CB-OG1 3.28Å; S296-T302 WeakPolarHBondContact CB-OG1 3.42Å; S296-T302 PolarHBondContact OG-OG1 2.87Å; A298-T302 PolarHBondContact O-N 3.11Å; A298-T302 VanDerWaalsContact O-N 3.12Å; A298-T302 PolarHBondContact O-OG1 2.9Å; V299-T302 PolarHBondContact O-N 3.33Å; T302-G304 PolarHBondContact O-N 3.16Å; T302-N305 PolarHBondContact O-N 3.02Å; T302-A306 WeakPolarHBondContact O-CB 3.45Å; T302-A306 PolarHBondContact O-N 3.11Å
303	F	91.5	Very high	87.9	Confident	0 Å²	0	43.8 Å²	43.8	0%	0	25%	0.25	C	S	.	.	H	α-helix	trans	-57.8	-47.5	171.3	175.1	-88.7	0	0	0	112	I201 I204 A283 Y284 A287 L288 V299 A300 V301 N305 A306 V307	I201-F303 HydrophobicContact CB-CE1 4.18Å; I201-F303 HydrophobicContact CB-CZ 4.48Å; I201-F303 HydrophobicContact CG1-CD1 4.1Å; I201-F303 HydrophobicContact CG1-CE1 3.91Å; I201-F303 HydrophobicContact CG2-CD1 4.46Å; I201-F303 HydrophobicContact CG2-CE1 4.04Å; I201-F303 HydrophobicContact CG2-CE2 4.4Å; I201-F303 HydrophobicContact CG2-CZ 4Å; I204-F303 HydrophobicContact CB-CE1 4.39Å; I204-F303 HydrophobicContact CB-CZ 3.93Å; I204-F303 HydrophobicContact CD1-CE1 4.26Å; I204-F303 HydrophobicContact CG2-CE1 4.18Å; I204-F303 HydrophobicContact CG2-CE2 4.47Å; I204-F303 HydrophobicContact CG2-CZ 3.59Å; A283-F303 HydrophobicContact CB-CE2 4.39Å; A283-F303 WeakPolarHBondContact O-CE2 3.17Å; Y284-F303 HydrophobicContact CD1-CB 3.96Å; Y284-F303 AromaticContact CD1-CD2 3.76Å; Y284-F303 HydrophobicContact CD1-CD2 3.76Å; Y284-F303 HydrophobicContact CD1-CE2 4.48Å; Y284-F303 AromaticContact CD1-CG 3.95Å; Y284-F303 HydrophobicContact CD1-CG 3.95Å; Y284-F303 HydrophobicContact CE1-CB 3.96Å; Y284-F303 HydrophobicContact CE1-CD2 4.29Å; Y284-F303 HydrophobicContact CE1-CG 4.04Å; A287-F303 HydrophobicContact CB-CD2 3.47Å; A287-F303 VanDerWaalsContact CB-CD2 3.47Å; A287-F303 HydrophobicContact CB-CE2 3.4Å; A287-F303 VanDerWaalsContact CB-CE2 3.4Å; L288-F303 HydrophobicContact CD1-CB 4.23Å; V299-F303 WeakPolarHBondContact O-CB 3.14Å; V299-F303 PolarHBondContact O-N 3.26Å; A300-F303 WeakPolarHBondContact O-CB 3.28Å; A300-F303 PolarHBondContact O-N 2.83Å; V301-F303 VanDerWaalsContact C-N 3.34Å; V301-F303 PolarHBondContact O-N 3.08Å; F303-N305 VanDerWaalsContact C-N 3.34Å; F303-N305 PolarHBondContact O-N 3.47Å; F303-A306 PolarHBondContact O-N 3.05Å; F303-V307 HydrophobicContact CE2-CG2 4.39Å; F303-V307 WeakPolarHBondContact O-CG2 3.42Å; F303-V307 PolarHBondContact O-N 3.48Å; F303-V307 VanDerWaalsContact O-N 3.15Å
304	G	89.6	Confident	87.6	Confident	0 Å²	0	47 Å²	47	0%	0	27%	0.267	C	S	.	.	H	α-helix	trans	-60.3	-42.7	178	0	0	0	0	0	112.4	A300 V301 T302 A306 V307 L308	A300-G304 PolarHBondContact O-N 3.23Å; V301-G304 PolarHBondContact O-N 3.41Å; V301-G304 VanDerWaalsContact O-N 3.12Å; T302-G304 PolarHBondContact O-N 3.16Å; G304-A306 VanDerWaalsContact C-N 3.31Å; G304-A306 PolarHBondContact O-N 3.22Å; G304-V307 PolarHBondContact O-N 3.42Å; G304-L308 VanDerWaalsContact O-CB 3.29Å; G304-L308 WeakPolarHBondContact O-CB 3.47Å; G304-L308 PolarHBondContact O-N 3.3Å
305	N	88.6	Confident	87.3	Confident	61 Å²	61	44.6 Å²	44.6	33%	0.326	25%	0.254	S	S	.	.	H	α-helix	trans	-63.5	-36.8	176.8	-71.2	-22.5	0	0	0	112.3	V301 T302 F303 K312	V301-N305 WeakPolarHBondContact O-CB 3.2Å; V301-N305 VanDerWaalsContact O-CG 3.27Å; V301-N305 PolarHBondContact O-N 2.87Å; V301-N305 PolarHBondContact O-ND2 3.15Å; T302-N305 PolarHBondContact O-N 3.02Å; F303-N305 VanDerWaalsContact C-N 3.34Å; F303-N305 PolarHBondContact O-N 3.47Å; N305-K312 WeakPolarHBondContact OD1-CD 3.37Å
306	A	87.6	Confident	87.2	Confident	61 Å²	61	41.2 Å²	41.2	50%	0.504	23%	0.226	S	C	.	.	H	α-helix	trans	-73.4	-28.8	-179.7	0	0	0	0	0	113.6	L288 T302 F303 G304	L288-A306 HydrophobicContact CD2-CB 3.96Å; T302-A306 WeakPolarHBondContact O-CB 3.45Å; T302-A306 PolarHBondContact O-N 3.11Å; F303-A306 PolarHBondContact O-N 3.05Å; G304-A306 VanDerWaalsContact C-N 3.31Å; G304-A306 PolarHBondContact O-N 3.22Å
307	V	88.7	Confident	87.2	Confident	47 Å²	47	45.4 Å²	45.4	29%	0.285	25%	0.246	S	C	.	.	H	α-helix	trans	-126.3	-29.3	-166.8	-159.9	0	0	0	0	115.5	I204 K208 A287 F303 G304	I204-V307 HydrophobicContact CG2-CB 4.05Å; I204-V307 HydrophobicContact CG2-CG1 3.34Å; I204-V307 HydrophobicContact CG2-CG2 4.45Å; K208-V307 HydrophobicContact CD-CG1 4.45Å; K208-V307 HydrophobicContact CD-CG2 4.4Å; K208-V307 VanDerWaalsContact CE-CG2 3.43Å; A287-V307 HydrophobicContact CB-CG2 3.95Å; F303-V307 HydrophobicContact CE2-CG2 4.39Å; F303-V307 WeakPolarHBondContact O-CG2 3.42Å; F303-V307 PolarHBondContact O-N 3.48Å; F303-V307 VanDerWaalsContact O-N 3.15Å; G304-V307 PolarHBondContact O-N 3.42Å
308	L	84.4	Confident	87.3	Confident	23 Å²	23	42.6 Å²	42.6	12%	0.12	23%	0.233	C	C	.	.			trans	-90.6	-10.3	-170.7	-71	172.6	0	0	0	114.7	L200 I204 G304 P310 F311 I315	L200-L308 HydrophobicContact CD2-CD1 4.27Å; L200-L308 HydrophobicContact CD2-CD2 4.34Å; I204-L308 HydrophobicContact CD1-CD2 3.35Å; I204-L308 HydrophobicContact CD1-CG 4.08Å; G304-L308 VanDerWaalsContact O-CB 3.29Å; G304-L308 WeakPolarHBondContact O-CB 3.47Å; G304-L308 PolarHBondContact O-N 3.3Å; L308-P310 VanDerWaalsContact O-N 3.16Å; L308-F311 HydrophobicContact CB-CB 4.23Å; L308-F311 PolarHBondContact O-N 2.96Å; L308-I315 HydrophobicContact CD1-CD1 3.92Å; L308-I315 HydrophobicContact CD1-CG1 3.5Å
309	G	84.9	Confident	87.2	Confident	42 Å²	42	42.6 Å²	42.6	43%	0.433	23%	0.233	S	C	.	.	G	3₁₀ helix	trans	54.1	-118.6	-179.4	0	0	0	0	0	111.6	F311 K312	G309-F311 VanDerWaalsContact C-N 3.26Å; G309-F311 PolarHBondContact O-N 3.36Å; G309-K312 WeakPolarHBondContact O-CB 3.47Å; G309-K312 WeakPolarHBondContact O-CG 3.25Å; G309-K312 PolarHBondContact O-N 3.36Å
310	P	83.2	Confident	87.1	Confident	86 Å²	86	42.9 Å²	42.9	56%	0.558	24%	0.235	S	C	*	.	G	3₁₀ helix	trans	-57.8	-35	176.8	-22.7	33.4	0	0	0	113.2	L308 K312 W313	L308-P310 VanDerWaalsContact O-N 3.16Å; P310-K312 PolarHBondContact O-N 2.84Å; P310-W313 HydrophobicContact CB-CH2 4.39Å; P310-W313 HydrophobicContact CB-CZ2 4.43Å; P310-W313 WeakPolarHBondContact O-CH2 3.31Å; P310-W313 WeakPolarHBondContact O-CZ2 3.39Å; P310-W313 VanDerWaalsContact O-CZ3 3.31Å; P310-W313 WeakPolarHBondContact O-CZ3 3.4Å
311	F	81.8	Confident	86.9	Confident	127 Å²	127	45.3 Å²	45.3	56%	0.557	25%	0.247	S	C	*	.	G	3₁₀ helix	trans	-78.8	9.9	-174.1	-60.7	-73.9	0	0	0	114.4	L308 G309 W313 I314	L308-F311 HydrophobicContact CB-CB 4.23Å; L308-F311 PolarHBondContact O-N 2.96Å; G309-F311 VanDerWaalsContact C-N 3.26Å; G309-F311 PolarHBondContact O-N 3.36Å; F311-W313 PolarHBondContact O-N 3.17Å; F311-W313 VanDerWaalsContact O-N 3.13Å; F311-I314 HydrophobicContact CB-CD1 3.99Å; F311-I314 HydrophobicContact CD1-CD1 4.04Å; F311-I314 HydrophobicContact CG-CD1 4.43Å; F311-I314 WeakPolarHBondContact O-CB 3.22Å; F311-I314 WeakPolarHBondContact O-CG1 3.46Å; F311-I314 PolarHBondContact O-N 2.92Å; F311-I314 VanDerWaalsContact O-N 3.09Å
312	K	82.7	Confident	86.7	Confident	83 Å²	83	45.3 Å²	45.3	36%	0.361	25%	0.247	S	C	.	.	G	3₁₀ helix	trans	-56.2	-29.3	-177.3	63.7	-179.7	-177.2	170.2	0	114.4	N305 G309 P310 I314 P316	N305-K312 WeakPolarHBondContact OD1-CD 3.37Å; G309-K312 WeakPolarHBondContact O-CB 3.47Å; G309-K312 WeakPolarHBondContact O-CG 3.25Å; G309-K312 PolarHBondContact O-N 3.36Å; P310-K312 PolarHBondContact O-N 2.84Å; K312-I314 VanDerWaalsContact C-N 3.26Å; K312-I314 PolarHBondContact O-N 3.22Å; K312-P316 WeakPolarHBondContact O-CD 3.26Å
313	W	83.6	Confident	86.7	Confident	147 Å²	147	43.8 Å²	43.8	56%	0.557	24%	0.238	S	C	*	.	G	3₁₀ helix	trans	-69.5	-16.7	179	39	72.1	0	0	0	114.5	P310 F311 I315 P316 I317	P310-W313 HydrophobicContact CB-CH2 4.39Å; P310-W313 HydrophobicContact CB-CZ2 4.43Å; P310-W313 WeakPolarHBondContact O-CH2 3.31Å; P310-W313 WeakPolarHBondContact O-CZ2 3.39Å; P310-W313 VanDerWaalsContact O-CZ3 3.31Å; P310-W313 WeakPolarHBondContact O-CZ3 3.4Å; F311-W313 PolarHBondContact O-N 3.17Å; F311-W313 VanDerWaalsContact O-N 3.13Å; W313-I315 VanDerWaalsContact C-N 3.32Å; W313-I315 PolarHBondContact O-N 2.71Å; W313-P316 WeakPolarHBondContact O-CD 3.3Å; W313-P316 WeakPolarHBondContact O-CG 3.26Å; W313-I317 WeakPolarHBondContact O-CD1 3.47Å; W313-I317 WeakPolarHBondContact O-CG1 3.41Å
314	I	85.6	Confident	86.5	Confident	69 Å²	69	46 Å²	46	35%	0.354	25%	0.247	S	C	.	.	H	α-helix	trans	-64.4	-40	178.2	-64.2	179.8	0	0	0	110.9	L200 F311 K312 S318	L200-I314 HydrophobicContact CD2-CG2 4.47Å; F311-I314 HydrophobicContact CB-CD1 3.99Å; F311-I314 HydrophobicContact CD1-CD1 4.04Å; F311-I314 HydrophobicContact CG-CD1 4.43Å; F311-I314 WeakPolarHBondContact O-CB 3.22Å; F311-I314 WeakPolarHBondContact O-CG1 3.46Å; F311-I314 PolarHBondContact O-N 2.92Å; F311-I314 VanDerWaalsContact O-N 3.09Å; K312-I314 VanDerWaalsContact C-N 3.26Å; K312-I314 PolarHBondContact O-N 3.22Å; I314-S318 VanDerWaalsContact O-CB 3.3Å; I314-S318 WeakPolarHBondContact O-CB 3.47Å; I314-S318 PolarHBondContact O-N 2.92Å; I314-S318 PolarHBondContact O-OG 3.41Å
315	I	87.1	Confident	86.3	Confident	0 Å²	0	46.3 Å²	46.3	0%	0	25%	0.25	C	C	.	.	H	α-helix	trans	-64.9	-57.2	-176.1	-58.1	-63.9	0	0	0	112.7	L200 I201 A300 L308 W313 I317 S318 V319	L200-I315 HydrophobicContact CD2-CD1 4.21Å; I201-I315 HydrophobicContact CD1-CD1 4.45Å; I201-I315 HydrophobicContact CG1-CD1 4.23Å; A300-I315 HydrophobicContact CB-CG2 3.63Å; A300-I315 VanDerWaalsContact O-CG2 3.32Å; A300-I315 WeakPolarHBondContact O-CG2 3.3Å; L308-I315 HydrophobicContact CD1-CD1 3.92Å; L308-I315 HydrophobicContact CD1-CG1 3.5Å; W313-I315 VanDerWaalsContact C-N 3.32Å; W313-I315 PolarHBondContact O-N 2.71Å; I315-I317 VanDerWaalsContact C-N 3.28Å; I315-I317 PolarHBondContact O-N 2.86Å; I315-S318 PolarHBondContact O-N 3.39Å; I315-S318 VanDerWaalsContact O-N 3.13Å; I315-V319 HydrophobicContact CG2-CG2 4.11Å; I315-V319 WeakPolarHBondContact O-CG2 3.19Å; I315-V319 PolarHBondContact O-N 3.36Å
316	P	88.6	Confident	86.1	Confident	5 Å²	5	44.2 Å²	44.2	3%	0.032	24%	0.242	C	C	.	.	H	α-helix	trans	-59.4	-39.1	-177.9	21.4	-31.9	0	0	0	112.4	Y145 A149 V301 K312 W313 V319 A320	Y145-P316 VanDerWaalsContact O-CB 3.29Å; Y145-P316 WeakPolarHBondContact O-CB 3.21Å; A149-P316 HydrophobicContact CB-CB 3.86Å; A149-P316 HydrophobicContact CB-CG 3.84Å; V301-P316 HydrophobicContact CG2-CB 3.88Å; V301-P316 HydrophobicContact CG2-CG 4.45Å; K312-P316 WeakPolarHBondContact O-CD 3.26Å; W313-P316 WeakPolarHBondContact O-CD 3.3Å; W313-P316 WeakPolarHBondContact O-CG 3.26Å; P316-V319 PolarHBondContact O-N 3.49Å; P316-A320 WeakPolarHBondContact O-CB 3.43Å; P316-A320 PolarHBondContact O-N 3.46Å
317	I	87.3	Confident	86.1	Confident	96 Å²	96	41.3 Å²	41.3	49%	0.492	22%	0.218	S	C	.	.	H	α-helix	trans	-64.6	-45	177.2	-64.3	173	0	0	0	110.8	W313 I315 A320 M321	W313-I317 WeakPolarHBondContact O-CD1 3.47Å; W313-I317 WeakPolarHBondContact O-CG1 3.41Å; I315-I317 VanDerWaalsContact C-N 3.28Å; I315-I317 PolarHBondContact O-N 2.86Å; I317-A320 PolarHBondContact O-N 3.4Å; I317-M321 HydrophobicContact CG2-CE 4.01Å; I317-M321 HydrophobicContact CG2-SD 4.48Å; I317-M321 WeakPolarHBondContact O-CG 3.25Å; I317-M321 PolarHBondContact O-N 3.47Å
318	S	86.6	Confident	86	Confident	13 Å²	13	39.2 Å²	39.2	9%	0.091	21%	0.206	C	C	.	.	H	α-helix	trans	-65.6	-40.8	179.6	-56.8	0	0	0	0	112.4	I314 I315 M321 S322	I314-S318 VanDerWaalsContact O-CB 3.3Å; I314-S318 WeakPolarHBondContact O-CB 3.47Å; I314-S318 PolarHBondContact O-N 2.92Å; I314-S318 PolarHBondContact O-OG 3.41Å; I315-S318 PolarHBondContact O-N 3.39Å; I315-S318 VanDerWaalsContact O-N 3.13Å; S318-M321 PolarHBondContact O-N 2.98Å; S318-S322 PolarHBondContact O-N 3.08Å
319	V	87.9	Confident	85.9	Confident	0 Å²	0	38.9 Å²	38.9	0%	0	21%	0.206	C	C	.	.	H	α-helix	trans	-69	-41.5	177.1	177.9	0	0	0	0	111.2	F59 Y145 A300 I315 P316 M321 S322 C323	F59-V319 HydrophobicContact CB-CG1 4.12Å; F59-V319 HydrophobicContact CD1-CG1 4.28Å; F59-V319 HydrophobicContact CD1-CG2 3.78Å; F59-V319 HydrophobicContact CD2-CB 4.39Å; F59-V319 HydrophobicContact CD2-CG1 3.54Å; F59-V319 HydrophobicContact CD2-CG2 4.14Å; F59-V319 HydrophobicContact CE1-CG2 3.58Å; F59-V319 HydrophobicContact CE2-CB 4.39Å; F59-V319 HydrophobicContact CE2-CG1 3.99Å; F59-V319 HydrophobicContact CE2-CG2 3.96Å; F59-V319 HydrophobicContact CG-CG1 3.7Å; F59-V319 HydrophobicContact CG-CG2 4.06Å; F59-V319 HydrophobicContact CZ-CG2 3.67Å; Y145-V319 HydrophobicContact CD1-CB 3.47Å; Y145-V319 VanDerWaalsContact CD1-CB 3.47Å; Y145-V319 HydrophobicContact CD1-CG1 3.32Å; Y145-V319 HydrophobicContact CD1-CG2 3.85Å; Y145-V319 HydrophobicContact CD2-CG1 3.93Å; Y145-V319 HydrophobicContact CE1-CB 3.86Å; Y145-V319 HydrophobicContact CE1-CG1 3.57Å; Y145-V319 HydrophobicContact CE1-CG2 3.76Å; Y145-V319 HydrophobicContact CE2-CG1 4.15Å; Y145-V319 HydrophobicContact CG-CB 4.04Å; Y145-V319 HydrophobicContact CG-CG1 3.51Å; A300-V319 HydrophobicContact CB-CG2 4.41Å; I315-V319 HydrophobicContact CG2-CG2 4.11Å; I315-V319 WeakPolarHBondContact O-CG2 3.19Å; I315-V319 PolarHBondContact O-N 3.36Å; P316-V319 PolarHBondContact O-N 3.49Å; V319-M321 PolarHBondContact O-N 3.46Å; V319-S322 VanDerWaalsContact O-CB 3.28Å; V319-S322 WeakPolarHBondContact O-CB 3.49Å; V319-S322 PolarHBondContact O-N 2.94Å; V319-S322 VanDerWaalsContact O-N 3.13Å; V319-C323 PolarHBondContact O-N 2.84Å; V319-C323 PolarHBondContact O-SG 3.06Å
320	A	88.9	Confident	85.9	Confident	8 Å²	8	37.8 Å²	37.8	7%	0.066	19%	0.192	C	C	.	.	H	α-helix	trans	-60	-45.1	175	0	0	0	0	0	111.2	F142 P316 I317 S322 C323 Y324	F142-A320 HydrophobicContact CD2-CB 3.88Å; F142-A320 VanDerWaalsContact CD2-O 3.3Å; F142-A320 WeakPolarHBondContact CD2-O 3.41Å; F142-A320 HydrophobicContact CE2-CB 3.88Å; P316-A320 WeakPolarHBondContact O-CB 3.43Å; P316-A320 PolarHBondContact O-N 3.46Å; I317-A320 PolarHBondContact O-N 3.4Å; A320-S322 VanDerWaalsContact C-N 3.31Å; A320-S322 PolarHBondContact O-N 3.16Å; A320-C323 PolarHBondContact O-N 2.76Å; A320-Y324 WeakPolarHBondContact O-CB 3.36Å; A320-Y324 PolarHBondContact O-N 3.43Å
321	M	85.8	Confident	86.2	Confident	51 Å²	51	33.7 Å²	33.7	25%	0.251	17%	0.165	S	C	.	.	H	α-helix	trans	-59.9	-40.5	173.4	-71.8	-173.8	-59.6	0	0	112.3	F190 A193 I317 S318 V319 Y324 G325	F190-M321 HydrophobicContact CB-CB 4.3Å; F190-M321 HydrophobicContact CD1-CB 3.78Å; F190-M321 HydrophobicContact CD1-CG 3.87Å; F190-M321 HydrophobicContact CD1-SD 3.78Å; F190-M321 HydrophobicContact CD2-CB 4.47Å; F190-M321 HydrophobicContact CE1-CB 4.18Å; F190-M321 HydrophobicContact CE1-CG 3.78Å; F190-M321 HydrophobicContact CE1-SD 3.67Å; F190-M321 HydrophobicContact CG-CB 3.94Å; F190-M321 HydrophobicContact CG-CG 4.46Å; F190-M321 HydrophobicContact CZ-CG 4.28Å; A193-M321 HydrophobicContact CB-CE 3.68Å; I317-M321 HydrophobicContact CG2-CE 4.01Å; I317-M321 HydrophobicContact CG2-SD 4.48Å; I317-M321 WeakPolarHBondContact O-CG 3.25Å; I317-M321 PolarHBondContact O-N 3.47Å; S318-M321 PolarHBondContact O-N 2.98Å; V319-M321 PolarHBondContact O-N 3.46Å; M321-Y324 PolarHBondContact O-N 2.87Å; M321-G325 PolarHBondContact O-N 2.96Å
322	S	87.3	Confident	86.2	Confident	1 Å²	1	28.8 Å²	28.8	1%	0.007	14%	0.144	C	C	.	.	H	α-helix	trans	-59.4	-49.2	175.2	-172.1	0	0	0	0	112	K194 S318 V319 A320 Y324 G325 G326	K194-S322 WeakPolarHBondContact CD-OG 3.47Å; S318-S322 PolarHBondContact O-N 3.08Å; V319-S322 VanDerWaalsContact O-CB 3.28Å; V319-S322 WeakPolarHBondContact O-CB 3.49Å; V319-S322 PolarHBondContact O-N 2.94Å; V319-S322 VanDerWaalsContact O-N 3.13Å; A320-S322 VanDerWaalsContact C-N 3.31Å; A320-S322 PolarHBondContact O-N 3.16Å; S322-Y324 PolarHBondContact O-N 2.95Å; S322-G325 PolarHBondContact O-N 3.35Å; S322-G326 PolarHBondContact O-N 3.46Å
323	C	89.3	Confident	86.1	Confident	0 Å²	0	26.7 Å²	26.7	0%	0	14%	0.142	C	C	.	.	H	α-helix	trans	-65.7	-39.6	-179.6	-61.4	0	0	0	0	111.3	I138 F142 V319 A320 G326 L327	I138-C323 HydrophobicContact CG2-CB 4.06Å; I138-C323 WeakPolarHBondContact CG2-O 3.2Å; F142-C323 HydrophobicContact CB-CB 3.66Å; F142-C323 HydrophobicContact CD2-CB 4.43Å; V319-C323 PolarHBondContact O-N 2.84Å; V319-C323 PolarHBondContact O-SG 3.06Å; A320-C323 PolarHBondContact O-N 2.76Å; C323-G326 PolarHBondContact O-N 2.69Å; C323-L327 VanDerWaalsContact O-CB 3.24Å; C323-L327 WeakPolarHBondContact O-CB 3.45Å; C323-L327 PolarHBondContact O-N 2.92Å
324	Y	88.1	Confident	86.2	Confident	47 Å²	47	19.7 Å²	19.7	18%	0.184	12%	0.116	C	C	.	.	H	α-helix	trans	-60.9	-46.1	175.2	-171.9	-81.9	0	0	0	111.8	F142 L172 V186 F190 A320 M321 S322 L327 N328	F142-Y324 HydrophobicContact CE2-CD2 4.46Å; L172-Y324 HydrophobicContact CD1-CD2 4.38Å; L172-Y324 HydrophobicContact CD1-CE2 4.32Å; L172-Y324 HydrophobicContact CD2-CD1 4.13Å; L172-Y324 HydrophobicContact CD2-CD2 4.47Å; L172-Y324 HydrophobicContact CD2-CE1 3.46Å; L172-Y324 VanDerWaalsContact CD2-CE1 3.46Å; L172-Y324 HydrophobicContact CD2-CE2 3.83Å; L172-Y324 WeakPolarHBondContact CD2-OH 3.41Å; L172-Y324 HydrophobicContact CG-CD2 4.46Å; L172-Y324 HydrophobicContact CG-CE1 4.4Å; L172-Y324 HydrophobicContact CG-CE2 3.91Å; V186-Y324 HydrophobicContact CG1-CD1 4.37Å; V186-Y324 HydrophobicContact CG1-CE1 3.92Å; F190-Y324 AromaticContact CD2-CD1 3.92Å; F190-Y324 HydrophobicContact CD2-CD1 3.92Å; F190-Y324 AromaticContact CE2-CD1 3.45Å; F190-Y324 HydrophobicContact CE2-CD1 3.45Å; F190-Y324 VanDerWaalsContact CE2-CD1 3.45Å; F190-Y324 AromaticContact CE2-CE1 3.98Å; F190-Y324 HydrophobicContact CE2-CE1 3.98Å; F190-Y324 HydrophobicContact CE2-CG 4.16Å; A320-Y324 WeakPolarHBondContact O-CB 3.36Å; A320-Y324 PolarHBondContact O-N 3.43Å; M321-Y324 PolarHBondContact O-N 2.87Å; S322-Y324 PolarHBondContact O-N 2.95Å; Y324-L327 PolarHBondContact O-N 3.26Å; Y324-N328 WeakPolarHBondContact O-CB 3.33Å; Y324-N328 PolarHBondContact O-N 3.28Å
325	G	83.9	Confident	86.1	Confident	6 Å²	6	16.7 Å²	16.7	6%	0.062	10%	0.101	C	C	.	.	H	α-helix	trans	-62.6	-44.5	176.3	0	0	0	0	0	112.8	M321 S322 N328 A329	M321-G325 PolarHBondContact O-N 2.96Å; S322-G325 PolarHBondContact O-N 3.35Å; G325-N328 PolarHBondContact O-N 3.5Å; G325-A329 PolarHBondContact O-N 3Å
326	G	84.2	Confident	85.7	Confident	17 Å²	17	22.3 Å²	22.3	18%	0.175	12%	0.122	C	C	.	.	H	α-helix	trans	-64.4	-40.1	176.9	0	0	0	0	0	113.1	S322 C323 A329 S330	S322-G326 PolarHBondContact O-N 3.46Å; C323-G326 PolarHBondContact O-N 2.69Å; G326-A329 PolarHBondContact O-N 3.06Å; G326-S330 WeakPolarHBondContact O-CB 3.28Å; G326-S330 PolarHBondContact O-N 3.1Å
327	L	89.4	Confident	85.4	Confident	0 Å²	0	22.3 Å²	22.3	0%	0	12%	0.122	C	C	.	.	H	α-helix	trans	-65.4	-42.9	177.2	-175.3	56.7	0	0	0	111.3	Q135 I138 I169 L172 C323 Y324 S330 I331	Q135-L327 HydrophobicContact CB-CD1 3.71Å; Q135-L327 HydrophobicContact CG-CD1 3.92Å; I138-L327 HydrophobicContact CB-CD1 4.45Å; I138-L327 HydrophobicContact CG2-CB 3.78Å; I169-L327 HydrophobicContact CG1-CD2 4.04Å; L172-L327 HydrophobicContact CD1-CB 3.76Å; L172-L327 HydrophobicContact CD1-CD2 3.53Å; L172-L327 HydrophobicContact CD1-CG 3.48Å; L172-L327 VanDerWaalsContact CD1-CG 3.48Å; C323-L327 VanDerWaalsContact O-CB 3.24Å; C323-L327 WeakPolarHBondContact O-CB 3.45Å; C323-L327 PolarHBondContact O-N 2.92Å; Y324-L327 PolarHBondContact O-N 3.26Å; L327-S330 PolarHBondContact O-N 3.36Å; L327-I331 HydrophobicContact CD1-CD1 4.17Å; L327-I331 HydrophobicContact CD1-CG1 4.41Å; L327-I331 HydrophobicContact CG-CD1 4.01Å; L327-I331 VanDerWaalsContact O-CG1 3.29Å; L327-I331 WeakPolarHBondContact O-CG1 3.07Å; L327-I331 PolarHBondContact O-N 3.34Å
328	N	86.7	Confident	85.3	Confident	3 Å²	3	17.7 Å²	17.7	2%	0.016	10%	0.099	C	C	.	.	H	α-helix	trans	-59.6	-47.3	174.8	-173.7	68.1	0	0	0	111.8	L172 N176 G183 Q187 Y324 G325 S330 I331 I332	L172-N328 HydrophobicContact CD1-CB 4.45Å; L172-N328 HydrophobicContact CD2-CB 3.81Å; N176-N328 PolarHBondContact ND2-OD1 3.26Å; N176-N328 PolarHBondContact OD1-OD1 2.88Å; G183-N328 PolarHBondContact O-ND2 3.07Å; Q187-N328 PolarHBondContact OE1-ND2 3.45Å; Y324-N328 WeakPolarHBondContact O-CB 3.33Å; Y324-N328 PolarHBondContact O-N 3.28Å; G325-N328 PolarHBondContact O-N 3.5Å; N328-S330 PolarHBondContact O-N 2.89Å; N328-I331 PolarHBondContact O-N 2.85Å; N328-I332 WeakPolarHBondContact O-CG1 3.45Å; N328-I332 PolarHBondContact O-N 3.04Å
329	A	81.1	Confident	84.9	Confident	16 Å²	16	18.5 Å²	18.5	13%	0.132	10%	0.1	C	C	.	.	H	α-helix	trans	-60	-44.6	177.8	0	0	0	0	0	111.9	G325 G326 I332 A333	G325-A329 PolarHBondContact O-N 3Å; G326-A329 PolarHBondContact O-N 3.06Å; A329-I332 PolarHBondContact O-N 2.68Å; A329-A333 WeakPolarHBondContact O-CB 3.35Å; A329-A333 PolarHBondContact O-N 2.99Å
330	S	85.9	Confident	84.4	Confident	18 Å²	18	20.1 Å²	20.1	13%	0.126	11%	0.11	C	C	.	.	H	α-helix	trans	-63	-44.3	177.6	177	0	0	0	0	112.3	Q135 G326 L327 N328 I332 A333 A334	Q135-S330 VanDerWaalsContact CG-OG 3.31Å; Q135-S330 WeakPolarHBondContact CG-OG 3.49Å; G326-S330 WeakPolarHBondContact O-CB 3.28Å; G326-S330 PolarHBondContact O-N 3.1Å; L327-S330 PolarHBondContact O-N 3.36Å; N328-S330 PolarHBondContact O-N 2.89Å; S330-I332 VanDerWaalsContact C-N 3.34Å; S330-I332 PolarHBondContact O-N 3.2Å; S330-A333 PolarHBondContact O-N 3Å; S330-A334 WeakPolarHBondContact O-CB 3.36Å; S330-A334 PolarHBondContact O-N 2.83Å
331	I	88.4	Confident	84.1	Confident	0 Å²	0	19.7 Å²	19.7	0%	0	11%	0.107	C	C	.	.	H	α-helix	trans	-60.8	-43.9	177.7	-71.7	167.7	0	0	0	111.1	Q135 L172 L327 N328 S335 L365	Q135-I331 HydrophobicContact CG-CG1 4.42Å; L172-I331 HydrophobicContact CB-CD1 3.84Å; L172-I331 HydrophobicContact CD1-CD1 4.25Å; L327-I331 HydrophobicContact CD1-CD1 4.17Å; L327-I331 HydrophobicContact CD1-CG1 4.41Å; L327-I331 HydrophobicContact CG-CD1 4.01Å; L327-I331 VanDerWaalsContact O-CG1 3.29Å; L327-I331 WeakPolarHBondContact O-CG1 3.07Å; L327-I331 PolarHBondContact O-N 3.34Å; N328-I331 PolarHBondContact O-N 2.85Å; I331-S335 WeakPolarHBondContact O-CB 3.48Å; I331-S335 PolarHBondContact O-N 3.46Å; I331-L365 HydrophobicContact CG2-CD2 3.52Å
332	I	82.3	Confident	84	Confident	24 Å²	24	17.4 Å²	17.4	12%	0.123	10%	0.096	C	C	.	.	H	α-helix	trans	-64.6	-47.3	177.5	-67.1	170.3	0	0	0	110.4	N328 A329 S330 A334 S335 R336	N328-I332 WeakPolarHBondContact O-CG1 3.45Å; N328-I332 PolarHBondContact O-N 3.04Å; A329-I332 PolarHBondContact O-N 2.68Å; S330-I332 VanDerWaalsContact C-N 3.34Å; S330-I332 PolarHBondContact O-N 3.2Å; I332-A334 PolarHBondContact O-N 3.28Å; I332-S335 PolarHBondContact O-N 2.9Å; I332-S335 PolarHBondContact O-OG 3.3Å; I332-R336 PolarHBondContact O-N 3.43Å; I332-R336 VanDerWaalsContact O-N 3.14Å
333	A	80.7	Confident	83.6	Confident	39 Å²	39	21.7 Å²	21.7	32%	0.322	11%	0.112	S	C	.	.	H	α-helix	trans	-60.3	-47	179.9	0	0	0	0	0	112.2	A329 S330 S335 R336 L337	A329-A333 WeakPolarHBondContact O-CB 3.35Å; A329-A333 PolarHBondContact O-N 2.99Å; S330-A333 PolarHBondContact O-N 3Å; A333-S335 VanDerWaalsContact C-N 3.34Å; A333-S335 PolarHBondContact O-N 3.5Å; A333-R336 PolarHBondContact O-N 2.87Å; A333-L337 PolarHBondContact O-N 2.8Å
334	A	85.9	Confident	83.2	Confident	1 Å²	1	26.8 Å²	26.8	1%	0.008	14%	0.136	C	C	.	.	H	α-helix	trans	-59.4	-44.3	176.7	0	0	0	0	0	111.5	E131 S330 I332 R336 L337 F338	E131-A334 HydrophobicContact CB-CB 3.91Å; E131-A334 HydrophobicContact CG-CB 3.84Å; S330-A334 WeakPolarHBondContact O-CB 3.36Å; S330-A334 PolarHBondContact O-N 2.83Å; I332-A334 PolarHBondContact O-N 3.28Å; A334-R336 VanDerWaalsContact C-N 3.3Å; A334-R336 PolarHBondContact O-N 2.93Å; A334-L337 WeakPolarHBondContact O-CB 3.42Å; A334-L337 PolarHBondContact O-N 3.23Å; A334-F338 HydrophobicContact CB-CE1 4.28Å; A334-F338 HydrophobicContact CB-CZ 4.05Å; A334-F338 WeakPolarHBondContact O-CD1 3.43Å; A334-F338 WeakPolarHBondContact O-CE1 3.37Å; A334-F338 WeakPolarHBondContact O-CG 3.48Å; A334-F338 PolarHBondContact O-N 2.93Å
335	S	83.4	Confident	83	Confident	5 Å²	5	26.7 Å²	26.7	4%	0.035	15%	0.149	C	C	.	.	H	α-helix	trans	-60.7	-37.5	178.4	74.8	0	0	0	0	113.1	I331 I332 A333 F338 F339	I331-S335 WeakPolarHBondContact O-CB 3.48Å; I331-S335 PolarHBondContact O-N 3.46Å; I332-S335 PolarHBondContact O-N 2.9Å; I332-S335 PolarHBondContact O-OG 3.3Å; A333-S335 VanDerWaalsContact C-N 3.34Å; A333-S335 PolarHBondContact O-N 3.5Å; S335-F338 PolarHBondContact O-N 3.44Å; S335-F339 WeakPolarHBondContact O-CB 3.26Å; S335-F339 PolarHBondContact O-N 3.49Å
336	R	78.6	Confident	83.1	Confident	118 Å²	118	27.3 Å²	27.3	45%	0.445	15%	0.15	S	C	.	.	H	α-helix	trans	-67.9	-42.6	175.1	-70.8	-177.6	-180	-159.4	-0.3	111.7	E254 I332 A333 A334 F338 F339 V340	E254-R336 IonicContact OE1-CZ 2.99Å; E254-R336 IonicContact OE1-NH1 3.99Å; E254-R336 PolarHBondContact OE1-NH1 2.75Å; I332-R336 PolarHBondContact O-N 3.43Å; I332-R336 VanDerWaalsContact O-N 3.14Å; A333-R336 PolarHBondContact O-N 2.87Å; A334-R336 VanDerWaalsContact C-N 3.3Å; A334-R336 PolarHBondContact O-N 2.93Å; R336-F338 VanDerWaalsContact C-N 3.28Å; R336-F338 PolarHBondContact O-N 2.99Å; R336-F339 PolarHBondContact O-N 3.35Å; R336-V340 WeakPolarHBondContact O-CG2 3.36Å; R336-V340 PolarHBondContact O-N 2.56Å
337	L	82.8	Confident	83.2	Confident	5 Å²	5	27.3 Å²	27.3	3%	0.026	15%	0.146	C	C	.	.	H	α-helix	trans	-59.2	-42.5	176	178	63	0	0	0	111.1	L123 A333 A334 V340 G341	L123-L337 HydrophobicContact CD1-CD1 3.99Å; L123-L337 HydrophobicContact CD1-CD2 4.4Å; L123-L337 HydrophobicContact CD1-CG 3.86Å; A333-L337 PolarHBondContact O-N 2.8Å; A334-L337 WeakPolarHBondContact O-CB 3.42Å; A334-L337 PolarHBondContact O-N 3.23Å; L337-V340 PolarHBondContact O-N 3.47Å; L337-G341 PolarHBondContact O-N 2.95Å
338	F	84.8	Confident	83	Confident	0 Å²	0	30.1 Å²	30.1	0%	0	16%	0.164	C	C	.	.	H	α-helix	trans	-69.3	-38.7	-178.7	-58.3	-2.4	0	0	0	110.8	I127 E131 A334 S335 R336 G341 A342 L347 A364 F367 N368	I127-F338 HydrophobicContact CB-CE1 4.04Å; I127-F338 HydrophobicContact CB-CZ 4.2Å; I127-F338 HydrophobicContact CD1-CD1 4.11Å; I127-F338 HydrophobicContact CD1-CE1 4.4Å; I127-F338 HydrophobicContact CG1-CD1 3.4Å; I127-F338 VanDerWaalsContact CG1-CD1 3.4Å; I127-F338 HydrophobicContact CG1-CE1 3.25Å; I127-F338 HydrophobicContact CG1-CE2 4.49Å; I127-F338 HydrophobicContact CG1-CG 4.18Å; I127-F338 HydrophobicContact CG1-CZ 3.84Å; I127-F338 HydrophobicContact CG2-CE1 4.47Å; I127-F338 HydrophobicContact CG2-CE2 4.47Å; I127-F338 HydrophobicContact CG2-CZ 4.24Å; E131-F338 HydrophobicContact CB-CZ 4.47Å; E131-F338 HydrophobicContact CG-CE1 4.18Å; E131-F338 HydrophobicContact CG-CZ 4.31Å; A334-F338 HydrophobicContact CB-CE1 4.28Å; A334-F338 HydrophobicContact CB-CZ 4.05Å; A334-F338 WeakPolarHBondContact O-CD1 3.43Å; A334-F338 WeakPolarHBondContact O-CE1 3.37Å; A334-F338 WeakPolarHBondContact O-CG 3.48Å; A334-F338 PolarHBondContact O-N 2.93Å; S335-F338 PolarHBondContact O-N 3.44Å; R336-F338 VanDerWaalsContact C-N 3.28Å; R336-F338 PolarHBondContact O-N 2.99Å; F338-G341 PolarHBondContact O-N 3.46Å; F338-A342 WeakPolarHBondContact O-CB 3.42Å; F338-A342 PolarHBondContact O-N 3.36Å; F338-L347 WeakPolarHBondContact O-CD1 3.43Å; F338-A364 HydrophobicContact CB-CB 4.21Å; F338-A364 HydrophobicContact CD2-CB 4.46Å; F338-F367 HydrophobicContact CD2-CD1 4.35Å; F338-F367 HydrophobicContact CE2-CD1 4.04Å; F338-N368 HydrophobicContact CD2-CB 4.44Å; F338-N368 HydrophobicContact CE2-CB 3.7Å; F338-N368 HydrophobicContact CZ-CB 4.49Å
339	F	77.1	Confident	82.7	Confident	29 Å²	29	33.3 Å²	33.3	13%	0.127	18%	0.182	C	C	.	.	H	α-helix	trans	-61.7	-47	174.6	179.8	-94.8	0	0	0	112.4	S335 R336 A342 R343 S352 I354 T495	S335-F339 WeakPolarHBondContact O-CB 3.26Å; S335-F339 PolarHBondContact O-N 3.49Å; R336-F339 PolarHBondContact O-N 3.35Å; F339-A342 PolarHBondContact O-N 2.95Å; F339-R343 HydrophobicContact CE1-CG 4.34Å; F339-R343 VanDerWaalsContact CE1-CZ 3.46Å; F339-R343 PolarHBondContact O-N 3.38Å; F339-S352 WeakPolarHBondContact CE2-O 3.06Å; F339-I354 HydrophobicContact CD2-CG1 4.49Å; F339-I354 HydrophobicContact CE2-CD1 3.76Å; F339-I354 HydrophobicContact CE2-CG1 3.71Å; F339-I354 HydrophobicContact CZ-CD1 3.93Å; F339-I354 HydrophobicContact CZ-CG1 4.38Å; F339-T495 HydrophobicContact CE2-CG2 4.41Å; F339-T495 HydrophobicContact CZ-CG2 4.12Å; F339-T495 WeakPolarHBondContact CZ-OG1 3.33Å
340	V	77.4	Confident	82.9	Confident	34 Å²	34	33 Å²	33	21%	0.206	18%	0.179	C	C	.	.	H	α-helix	trans	-64.6	-44.3	176.9	172.4	0	0	0	0	111	Y107 R336 L337 A342 R343 E344	Y107-V340 HydrophobicContact CD1-CG1 4.47Å; Y107-V340 HydrophobicContact CE1-CG1 4.29Å; R336-V340 WeakPolarHBondContact O-CG2 3.36Å; R336-V340 PolarHBondContact O-N 2.56Å; L337-V340 PolarHBondContact O-N 3.47Å; V340-A342 VanDerWaalsContact C-N 3.27Å; V340-A342 PolarHBondContact O-N 3.4Å; V340-R343 WeakPolarHBondContact O-CB 3.35Å; V340-R343 PolarHBondContact O-N 3.05Å; V340-R343 VanDerWaalsContact O-N 3.12Å; V340-E344 PolarHBondContact O-N 3.06Å; V340-E344 VanDerWaalsContact O-N 3.1Å
341	G	83.3	Confident	82.8	Confident	0 Å²	0	33 Å²	33	0%	0	18%	0.177	C	C	.	.	H	α-helix	trans	-60.2	-35.5	176.7	0	0	0	0	0	113.6	L337 F338 H346 L347	L337-G341 PolarHBondContact O-N 2.95Å; F338-G341 PolarHBondContact O-N 3.46Å; G341-H346 WeakPolarHBondContact O-CB 3.26Å; G341-H346 PolarHBondContact O-N 3.32Å; G341-H346 VanDerWaalsContact O-N 3.12Å; G341-L347 PolarHBondContact O-N 3.47Å
342	A	83.1	Confident	82.4	Confident	2 Å²	2	33.1 Å²	33.1	2%	0.017	18%	0.178	C	C	.	.	H	α-helix	trans	-73.4	-33.4	174.8	0	0	0	0	0	112.9	F338 F339 V340 G345 L347 L351 S352	F338-A342 WeakPolarHBondContact O-CB 3.42Å; F338-A342 PolarHBondContact O-N 3.36Å; F339-A342 PolarHBondContact O-N 2.95Å; V340-A342 VanDerWaalsContact C-N 3.27Å; V340-A342 PolarHBondContact O-N 3.4Å; A342-G345 PolarHBondContact O-N 3.43Å; A342-L347 HydrophobicContact CB-CB 3.86Å; A342-L351 HydrophobicContact CB-CB 4.25Å; A342-S352 VanDerWaalsContact CB-CB 3.5Å
343	R	78.1	Confident	82.5	Confident	92 Å²	92	32 Å²	32	35%	0.347	17%	0.172	S	C	.	.	H	α-helix	trans	-65.1	-36.9	173.7	-79.3	-176.9	159.8	-160.6	-5.2	113.2	F339 V340 G345 T495	F339-R343 HydrophobicContact CE1-CG 4.34Å; F339-R343 VanDerWaalsContact CE1-CZ 3.46Å; F339-R343 PolarHBondContact O-N 3.38Å; V340-R343 WeakPolarHBondContact O-CB 3.35Å; V340-R343 PolarHBondContact O-N 3.05Å; V340-R343 VanDerWaalsContact O-N 3.12Å; R343-G345 PolarHBondContact O-N 3.44Å; R343-G345 VanDerWaalsContact O-N 3.17Å; R343-T495 PolarHBondContact NE-OG1 2.82Å; R343-T495 VanDerWaalsContact NH2-CB 3.26Å; R343-T495 PolarHBondContact NH2-OG1 2.97Å
344	E	82.8	Confident	82.7	Confident	106 Å²	106	31.7 Å²	31.7	50%	0.495	16%	0.164	S	C	.	.	T	Hydrogen-bonded Turn	trans	-74.5	6.3	174.9	-67.1	-69.8	165.3	0	0	113.2	Y107 V340 H346	Y107-E344 HydrophobicContact CE1-CG 4.11Å; Y107-E344 VanDerWaalsContact OH-CB 3.26Å; Y107-E344 WeakPolarHBondContact OH-CB 3.47Å; V340-E344 PolarHBondContact O-N 3.06Å; V340-E344 VanDerWaalsContact O-N 3.1Å; E344-H346 PolarHBondContact O-N 3.01Å
345	G	83.4	Confident	82.7	Confident	45 Å²	45	32.9 Å²	32.9	46%	0.464	17%	0.17	S	C	.	.	T	Hydrogen-bonded Turn	trans	71.8	8.8	179.6	0	0	0	0	0	114.5	A342 R343	A342-G345 PolarHBondContact O-N 3.43Å; R343-G345 PolarHBondContact O-N 3.44Å; R343-G345 VanDerWaalsContact O-N 3.17Å
346	H	85.5	Confident	82.6	Confident	20 Å²	20	34.3 Å²	34.3	9%	0.093	18%	0.182	C	C	.	.	S	Bend	trans	-85.6	-13.2	179.3	-75.4	170.4	0	0	0	113.5	Y107 F120 L123 G341 E344 I464	Y107-H346 AromaticContact CE2-ND1 3.74Å; Y107-H346 AromaticContact CZ-ND1 3.69Å; Y107-H346 PolarHBondContact OH-CE1 3.18Å; Y107-H346 PolarHBondContact OH-ND1 3.37Å; F120-H346 HydrophobicContact CD2-CB 4.04Å; F120-H346 WeakPolarHBondContact CD2-O 3.35Å; F120-H346 VanDerWaalsContact CE2-O 3.25Å; F120-H346 WeakPolarHBondContact CE2-O 3.24Å; L123-H346 HydrophobicContact CD2-CB 3.85Å; G341-H346 WeakPolarHBondContact O-CB 3.26Å; G341-H346 PolarHBondContact O-N 3.32Å; G341-H346 VanDerWaalsContact O-N 3.12Å; E344-H346 PolarHBondContact O-N 3.01Å; H346-I464 HydrophobicContact CB-CD1 4.27Å
347	L	86.4	Confident	82.8	Confident	16 Å²	16	35.3 Å²	35.3	8%	0.084	19%	0.192	C	C	.	.	S	Bend	trans	-130.9	162	176.1	-65.3	170	0	0	0	111.1	L123 I127 F338 G341 A342 N349 L351	L123-L347 HydrophobicContact CD1-CD1 4.36Å; L123-L347 HydrophobicContact CD2-CD1 3.9Å; L123-L347 HydrophobicContact CD2-CD2 4.4Å; L123-L347 HydrophobicContact CD2-CG 3.85Å; L123-L347 HydrophobicContact CG-CD1 4.23Å; L123-L347 HydrophobicContact CG-CG 4.46Å; I127-L347 HydrophobicContact CD1-CD1 3.49Å; I127-L347 VanDerWaalsContact CD1-CD1 3.49Å; I127-L347 HydrophobicContact CD1-CD2 3.53Å; I127-L347 HydrophobicContact CD1-CG 4.09Å; F338-L347 WeakPolarHBondContact O-CD1 3.43Å; G341-L347 PolarHBondContact O-N 3.47Å; A342-L347 HydrophobicContact CB-CB 3.86Å; L347-N349 PolarHBondContact O-N 2.94Å; L347-L351 HydrophobicContact CB-CD1 4.42Å; L347-L351 HydrophobicContact CD1-CD1 4.46Å
348	P	85	Confident	82.5	Confident	59 Å²	59	40.5 Å²	40.5	38%	0.383	21%	0.211	S	C	.	.			trans	-55.2	138.6	174.4	-26.3	35.7	0	0	0	112.8	S350 L351	P348-S350 PolarHBondContact O-N 3.48Å; P348-L351 PolarHBondContact O-N 2.82Å
349	N	81.4	Confident	82.4	Confident	71 Å²	71	49.3 Å²	49.3	38%	0.38	25%	0.246	S	C	.	.	T	Hydrogen-bonded Turn	trans	-57.9	-19	178.5	-70.2	-11.8	0	0	0	114	L347 L351 S352 M353 L494	L347-N349 PolarHBondContact O-N 2.94Å; N349-L351 PolarHBondContact O-N 2.93Å; N349-S352 PolarHBondContact O-N 3.41Å; N349-S352 PolarHBondContact O-OG 3.36Å; N349-M353 WeakPolarHBondContact O-CG 3.35Å; N349-L494 HydrophobicContact CB-CD2 4.22Å
350	S	83.7	Confident	82.7	Confident	10 Å²	10	48 Å²	48	7%	0.07	24%	0.24	C	C	.	.	T	Hydrogen-bonded Turn	trans	-61.9	-30.3	172.8	55	0	0	0	0	113.1	P348 P363	P348-S350 PolarHBondContact O-N 3.48Å; S350-P363 WeakPolarHBondContact O-CB 3.37Å; S350-P363 WeakPolarHBondContact O-CG 3.48Å
351	L	84.1	Confident	83.1	Confident	17 Å²	17	47.4 Å²	47.4	9%	0.089	24%	0.237	C	C	.	.	T	Hydrogen-bonded Turn	trans	-83.9	-16.3	-178.6	-62.5	178.5	0	0	0	113.4	A342 L347 P348 N349 M353 F367	A342-L351 HydrophobicContact CB-CB 4.25Å; L347-L351 HydrophobicContact CB-CD1 4.42Å; L347-L351 HydrophobicContact CD1-CD1 4.46Å; P348-L351 PolarHBondContact O-N 2.82Å; N349-L351 PolarHBondContact O-N 2.93Å; L351-M353 VanDerWaalsContact C-N 3.34Å; L351-F367 HydrophobicContact CD2-CB 3.99Å; L351-F367 HydrophobicContact CD2-CG 4.29Å
352	S	81.1	Confident	83.3	Confident	3 Å²	3	47.7 Å²	47.7	2%	0.021	24%	0.239	C	C	.	.	T	Hydrogen-bonded Turn	trans	-90	7.2	172.3	51.7	0	0	0	0	113.7	F339 A342 N349	F339-S352 WeakPolarHBondContact CE2-O 3.06Å; A342-S352 VanDerWaalsContact CB-CB 3.5Å; N349-S352 PolarHBondContact O-N 3.41Å; N349-S352 PolarHBondContact O-OG 3.36Å
353	M	84.3	Confident	83.6	Confident	0 Å²	0	48.1 Å²	48.1	0%	0	24%	0.241	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-83.6	149.1	-179.2	-57.8	-178.5	180	0	0	112.7	N349 L351 P363 T483 T486 Q487 C492 C493 L494	N349-M353 WeakPolarHBondContact O-CG 3.35Å; L351-M353 VanDerWaalsContact C-N 3.34Å; M353-P363 HydrophobicContact CB-CG 4.29Å; M353-T483 HydrophobicContact CE-CG2 3.2Å; M353-T486 HydrophobicContact SD-CG2 3.9Å; M353-Q487 HydrophobicContact CE-CG 3.61Å; M353-Q487 HydrophobicContact SD-CG 3.6Å; M353-Q487 VanDerWaalsContact SD-CG 3.6Å; M353-C492 HydrophobicContact CB-CB 3.79Å; M353-C492 HydrophobicContact SD-CB 4.27Å; M353-C493 WeakPolarHBondContact CA-O 3.17Å; M353-L494 HydrophobicContact CE-CD1 4.1Å; M353-L494 HydrophobicContact CG-CG 4.3Å
354	I	84.9	Confident	84.1	Confident	32 Å²	32	43.8 Å²	43.8	16%	0.164	23%	0.225	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-120.1	141.4	176.8	-58.1	-170.7	0	0	0	109.2	F339 Y359 C492 C493 T495	F339-I354 HydrophobicContact CD2-CG1 4.49Å; F339-I354 HydrophobicContact CE2-CD1 3.76Å; F339-I354 HydrophobicContact CE2-CG1 3.71Å; F339-I354 HydrophobicContact CZ-CD1 3.93Å; F339-I354 HydrophobicContact CZ-CG1 4.38Å; I354-Y359 VanDerWaalsContact CG2-CA 3.4Å; I354-C492 CarbonylContact O-C 3.23Å; I354-C492 WeakPolarHBondContact O-CA 3.47Å; I354-C492 WeakPolarHBondContact O-CB 3.23Å; I354-C493 PolarHBondContact N-O 2.79Å; I354-C493 PolarHBondContact O-N 2.81Å; I354-T495 HydrophobicContact CB-CG2 4.5Å; I354-T495 HydrophobicContact CD1-CG2 3.32Å; I354-T495 HydrophobicContact CG1-CG2 3.84Å
355	Q	85.1	Confident	84.5	Confident	27 Å²	27	38.8 Å²	38.8	13%	0.126	20%	0.202	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-70.7	129.7	175.3	-174	160	-5.4	0	0	111.6	E357 R358 Y359 T360 V362	Q355-E357 PolarHBondContact O-N 3.4Å; Q355-R358 PolarHBondContact O-N 3.26Å; Q355-Y359 WeakPolarHBondContact O-CA 3.46Å; Q355-Y359 PolarHBondContact O-N 3.07Å; Q355-T360 PolarHBondContact N-O 3.39Å; Q355-V362 HydrophobicContact CB-CG2 4.11Å
356	A	81.8	Confident	84.9	Confident	35 Å²	35	40.4 Å²	40.4	29%	0.289	20%	0.199	S	C	.	.	T	Hydrogen-bonded Turn	trans	-64.8	-32.6	-166.7	0	0	0	0	0	114.7	Y491	A356-Y491 HydrophobicContact CB-CD1 3.87Å; A356-Y491 HydrophobicContact CB-CE1 3.74Å; A356-Y491 PolarHBondContact N-O 2.87Å
357	E	81.8	Confident	85.2	Confident	139 Å²	139	42.6 Å²	42.6	65%	0.65	21%	0.208	S	C	*	.	T	Hydrogen-bonded Turn	trans	-89	-32	-178.2	-64.3	-178.3	168	0	0	113.1	Q355 Y491	Q355-E357 PolarHBondContact O-N 3.4Å; E357-Y491 HydrophobicContact CG-CD1 4.36Å; E357-Y491 HydrophobicContact CG-CE1 4.17Å
358	R	78.2	Confident	85.4	Confident	113 Å²	113	41.8 Å²	41.8	43%	0.426	20%	0.204	S	C	.	.	T	Hydrogen-bonded Turn	trans	-107	-15.2	-167.5	-63.5	174.2	-176.9	-175.1	0.5	113.3	C177 A178 Q355 T360	C177-R358 WeakPolarHBondContact O-CD 3.32Å; A178-R358 WeakPolarHBondContact O-CD 3.29Å; Q355-R358 PolarHBondContact O-N 3.26Å; R358-T360 HydrophobicContact CB-CG2 4.14Å; R358-T360 WeakPolarHBondContact O-CG2 3.3Å; R358-T360 PolarHBondContact O-N 3.09Å
359	Y	82.4	Confident	85.7	Confident	185 Å²	185	39 Å²	39	73%	0.725	19%	0.186	S	C	*	.			trans	57.3	36	-177.2	-56.2	-87.5	0	0	0	113.1	I354 Q355	I354-Y359 VanDerWaalsContact CG2-CA 3.4Å; Q355-Y359 WeakPolarHBondContact O-CA 3.46Å; Q355-Y359 PolarHBondContact O-N 3.07Å
360	T	82.3	Confident	86.3	Confident	2 Å²	2	40.5 Å²	40.5	1%	0.012	19%	0.194	C	C	.	.			trans	-113.3	143.1	-179.3	58	0	0	0	0	112	C177 V180 Q355 R358 V362	C177-T360 PolarHBondContact O-OG1 3.4Å; V180-T360 HydrophobicContact CG2-CG2 3.51Å; Q355-T360 PolarHBondContact N-O 3.39Å; R358-T360 HydrophobicContact CB-CG2 4.14Å; R358-T360 WeakPolarHBondContact O-CG2 3.3Å; R358-T360 PolarHBondContact O-N 3.09Å; T360-V362 VanDerWaalsContact C-N 3.26Å; T360-V362 PolarHBondContact O-N 3.26Å; T360-V362 WeakPolarHBondContact OG1-CG2 3.4Å
361	P	86.4	Confident	86.8	Confident	22 Å²	22	41.2 Å²	41.2	14%	0.143	20%	0.196	C	C	.	.			trans	-82.2	65.6	-179.2	34.5	-36.1	0	0	0	111.6	A364 L365	P361-A364 HydrophobicContact CB-CB 4.4Å; P361-A364 PolarHBondContact O-N 3.34Å; P361-L365 WeakPolarHBondContact O-CG 3.45Å; P361-L365 PolarHBondContact O-N 3.26Å; P361-L365 VanDerWaalsContact O-N 3.11Å
362	V	88.5	Confident	87.2	Confident	6 Å²	6	40.4 Å²	40.4	4%	0.036	19%	0.192	C	C	.	.	H	α-helix	trans	-56.6	-44	-172.9	175.7	0	0	0	0	114.4	C177 Q355 T360 A364 L365 I366 L490	C177-V362 HydrophobicContact CB-CG1 4.49Å; C177-V362 HydrophobicContact CB-CG2 3.99Å; Q355-V362 HydrophobicContact CB-CG2 4.11Å; T360-V362 VanDerWaalsContact C-N 3.26Å; T360-V362 PolarHBondContact O-N 3.26Å; T360-V362 WeakPolarHBondContact OG1-CG2 3.4Å; V362-A364 VanDerWaalsContact C-N 3.33Å; V362-A364 PolarHBondContact O-N 3.39Å; V362-L365 PolarHBondContact O-N 2.96Å; V362-I366 HydrophobicContact CG1-CD1 3.61Å; V362-I366 HydrophobicContact CG1-CG1 4.16Å; V362-I366 WeakPolarHBondContact O-CG1 3.29Å; V362-I366 PolarHBondContact O-N 2.85Å; V362-L490 HydrophobicContact CG1-CD1 4.16Å; V362-L490 HydrophobicContact CG1-CD2 4.16Å
363	P	89.6	Confident	87.9	Confident	11 Å²	11	42.8 Å²	42.8	7%	0.071	20%	0.204	C	C	.	.	H	α-helix	trans	-61.4	-40.1	179.7	-24.8	35.9	0	0	0	113.2	S350 M353 I366 F367 T486 L490	S350-P363 WeakPolarHBondContact O-CB 3.37Å; S350-P363 WeakPolarHBondContact O-CG 3.48Å; M353-P363 HydrophobicContact CB-CG 4.29Å; P363-I366 PolarHBondContact O-N 3.31Å; P363-F367 WeakPolarHBondContact O-CB 3.46Å; P363-F367 PolarHBondContact O-N 3.29Å; P363-T486 HydrophobicContact CB-CG2 3.91Å; P363-T486 HydrophobicContact CG-CG2 3.44Å; P363-T486 VanDerWaalsContact CG-CG2 3.44Å; P363-L490 HydrophobicContact CB-CD1 4.44Å; P363-L490 HydrophobicContact CG-CD1 3.89Å
364	A	88.1	Confident	88.4	Confident	0 Å²	0	47.2 Å²	47.2	0%	0	23%	0.227	C	C	.	.	H	α-helix	trans	-66.4	-40.9	176.9	0	0	0	0	0	111.7	F338 P361 V362 F367 N368	F338-A364 HydrophobicContact CB-CB 4.21Å; F338-A364 HydrophobicContact CD2-CB 4.46Å; P361-A364 HydrophobicContact CB-CB 4.4Å; P361-A364 PolarHBondContact O-N 3.34Å; V362-A364 VanDerWaalsContact C-N 3.33Å; V362-A364 PolarHBondContact O-N 3.39Å; A364-F367 PolarHBondContact O-N 3.43Å; A364-N368 VanDerWaalsContact O-CB 3.27Å; A364-N368 WeakPolarHBondContact O-CB 3.27Å; A364-N368 PolarHBondContact O-N 3.41Å
365	L	90	Very high	88.8	Confident	2 Å²	2	46.8 Å²	46.8	1%	0.01	22%	0.224	C	C	.	.	H	α-helix	trans	-63	-44.3	176.2	-71.7	168.5	0	0	0	112.2	I173 N176 I331 P361 V362 G369	I173-L365 HydrophobicContact CG2-CB 4.45Å; N176-L365 HydrophobicContact CB-CD1 4Å; N176-L365 HydrophobicContact CB-CD2 4.15Å; I331-L365 HydrophobicContact CG2-CD2 3.52Å; P361-L365 WeakPolarHBondContact O-CG 3.45Å; P361-L365 PolarHBondContact O-N 3.26Å; P361-L365 VanDerWaalsContact O-N 3.11Å; V362-L365 PolarHBondContact O-N 2.96Å; L365-G369 PolarHBondContact O-N 2.88Å
366	I	91.9	Very high	89.3	Confident	79 Å²	79	46 Å²	46	41%	0.405	22%	0.22	S	C	.	.	H	α-helix	trans	-64.5	-45.1	177.6	-67.8	172.1	0	0	0	110.5	V362 P363 G369 L370 L490	V362-I366 HydrophobicContact CG1-CD1 3.61Å; V362-I366 HydrophobicContact CG1-CG1 4.16Å; V362-I366 WeakPolarHBondContact O-CG1 3.29Å; V362-I366 PolarHBondContact O-N 2.85Å; P363-I366 PolarHBondContact O-N 3.31Å; I366-G369 PolarHBondContact O-N 3.27Å; I366-L370 WeakPolarHBondContact O-CB 3.37Å; I366-L370 PolarHBondContact O-N 3.01Å; I366-L490 HydrophobicContact CD1-CD1 4.12Å; I366-L490 HydrophobicContact CD1-CD2 4.09Å
367	F	91.5	Very high	89.7	Confident	65 Å²	65	49.1 Å²	49.1	29%	0.285	24%	0.239	S	C	.	.	H	α-helix	trans	-61.1	-49.4	178.3	179.6	-85.5	0	0	0	111.5	I127 L128 F338 L351 P363 A364 G369 L370 M371	I127-F367 HydrophobicContact CG2-CD1 4.17Å; I127-F367 HydrophobicContact CG2-CE1 3.25Å; I127-F367 HydrophobicContact CG2-CZ 3.84Å; L128-F367 HydrophobicContact CD2-CZ 4.48Å; F338-F367 HydrophobicContact CD2-CD1 4.35Å; F338-F367 HydrophobicContact CE2-CD1 4.04Å; L351-F367 HydrophobicContact CD2-CB 3.99Å; L351-F367 HydrophobicContact CD2-CG 4.29Å; P363-F367 WeakPolarHBondContact O-CB 3.46Å; P363-F367 PolarHBondContact O-N 3.29Å; A364-F367 PolarHBondContact O-N 3.43Å; F367-G369 VanDerWaalsContact C-N 3.28Å; F367-G369 PolarHBondContact O-N 2.92Å; F367-L370 PolarHBondContact O-N 3.49Å; F367-M371 HydrophobicContact CD1-CG 4.22Å; F367-M371 HydrophobicContact CE1-CG 3.58Å; F367-M371 HydrophobicContact CZ-CG 3.79Å; F367-M371 HydrophobicContact CZ-SD 4.17Å; F367-M371 WeakPolarHBondContact O-CG 3.27Å; F367-M371 PolarHBondContact O-N 3.2Å
368	N	90.9	Very high	90.1	Very high	0 Å²	0	43.8 Å²	43.8	0%	0	22%	0.216	C	C	.	.	H	α-helix	trans	-57.1	-44.7	176.8	-175.2	51.8	0	0	0	111.3	Q135 F338 A364 M371 G372	Q135-N368 PolarHBondContact NE2-ND2 3.29Å; Q135-N368 PolarHBondContact NE2-OD1 3.17Å; Q135-N368 PolarHBondContact OE1-ND2 2.81Å; Q135-N368 PolarHBondContact OE1-OD1 3.38Å; F338-N368 HydrophobicContact CD2-CB 4.44Å; F338-N368 HydrophobicContact CE2-CB 3.7Å; F338-N368 HydrophobicContact CZ-CB 4.49Å; A364-N368 VanDerWaalsContact O-CB 3.27Å; A364-N368 WeakPolarHBondContact O-CB 3.27Å; A364-N368 PolarHBondContact O-N 3.41Å; N368-M371 PolarHBondContact O-N 3.04Å; N368-G372 PolarHBondContact O-N 3.4Å
369	G	91.9	Very high	90.4	Very high	1 Å²	1	45.4 Å²	45.4	1%	0.01	23%	0.228	C	C	.	.	H	α-helix	trans	-61.3	-46.1	177.6	0	0	0	0	0	114.6	L365 I366 F367 M371 G372 L373	L365-G369 PolarHBondContact O-N 2.88Å; I366-G369 PolarHBondContact O-N 3.27Å; F367-G369 VanDerWaalsContact C-N 3.28Å; F367-G369 PolarHBondContact O-N 2.92Å; G369-M371 VanDerWaalsContact C-N 3.3Å; G369-M371 PolarHBondContact O-N 3.06Å; G369-G372 PolarHBondContact O-N 2.84Å; G369-L373 WeakPolarHBondContact O-CG 3.37Å; G369-L373 PolarHBondContact O-N 3.38Å
370	L	94.2	Very high	90.7	Very high	101 Å²	101	40.2 Å²	40.2	53%	0.529	21%	0.213	S	C	.	.	H	α-helix	trans	-60.3	-43.3	176.4	-178.7	65	0	0	0	111	I366 F367 L373 I374	I366-L370 WeakPolarHBondContact O-CB 3.37Å; I366-L370 PolarHBondContact O-N 3.01Å; F367-L370 PolarHBondContact O-N 3.49Å; L370-L373 PolarHBondContact O-N 3.33Å; L370-I374 HydrophobicContact CG-CD1 4.42Å; L370-I374 WeakPolarHBondContact O-CG1 3.37Å; L370-I374 PolarHBondContact O-N 3.18Å
371	M	93.6	Very high	91	Very high	25 Å²	25	41.2 Å²	41.2	12%	0.123	22%	0.219	C	C	.	.	H	α-helix	trans	-62.6	-43.3	174.9	-70.9	-59.9	-56.4	0	0	111.7	L128 P132 F367 N368 G369 L373 I374 F375	L128-M371 HydrophobicContact CD2-CE 4.02Å; L128-M371 HydrophobicContact CD2-SD 4.38Å; L128-M371 WeakPolarHBondContact O-CE 3.46Å; P132-M371 HydrophobicContact CB-CB 3.87Å; P132-M371 HydrophobicContact CG-CB 3.53Å; P132-M371 HydrophobicContact CG-CE 4.33Å; P132-M371 HydrophobicContact CG-CG 4.39Å; F367-M371 HydrophobicContact CD1-CG 4.22Å; F367-M371 HydrophobicContact CE1-CG 3.58Å; F367-M371 HydrophobicContact CZ-CG 3.79Å; F367-M371 HydrophobicContact CZ-SD 4.17Å; F367-M371 WeakPolarHBondContact O-CG 3.27Å; F367-M371 PolarHBondContact O-N 3.2Å; N368-M371 PolarHBondContact O-N 3.04Å; G369-M371 VanDerWaalsContact C-N 3.3Å; G369-M371 PolarHBondContact O-N 3.06Å; M371-L373 VanDerWaalsContact C-N 3.3Å; M371-L373 PolarHBondContact O-N 3.07Å; M371-I374 PolarHBondContact O-N 2.65Å; M371-I374 VanDerWaalsContact O-N 3.15Å; M371-I374 HydrophobicContact SD-CD1 4.15Å; M371-F375 HydrophobicContact CE-CD2 4.41Å; M371-F375 HydrophobicContact CE-CE2 3.88Å; M371-F375 WeakPolarHBondContact O-CD2 3.49Å; M371-F375 PolarHBondContact O-N 3.39Å; M371-F375 VanDerWaalsContact O-N 3.07Å
372	G	93.4	Very high	91.1	Very high	0 Å²	0	41.7 Å²	41.7	0%	0	22%	0.219	C	C	.	.	H	α-helix	trans	-56.9	-42.4	174.4	0	0	0	0	0	112.6	N368 G369 F375 L376	N368-G372 PolarHBondContact O-N 3.4Å; G369-G372 PolarHBondContact O-N 2.84Å; G372-F375 PolarHBondContact O-N 3.06Å; G372-L376 PolarHBondContact O-N 3.04Å
373	L	95.3	Very high	91.2	Very high	54 Å²	54	43.9 Å²	43.9	28%	0.283	23%	0.229	S	C	.	.	H	α-helix	trans	-64.4	-38.1	175.7	-66.9	177.4	0	0	0	112.9	A166 I169 G369 L370 M371 F375 L376	A166-L373 HydrophobicContact CB-CD2 3.67Å; I169-L373 HydrophobicContact CB-CD2 4.48Å; I169-L373 HydrophobicContact CG2-CD2 4.33Å; G369-L373 WeakPolarHBondContact O-CG 3.37Å; G369-L373 PolarHBondContact O-N 3.38Å; L370-L373 PolarHBondContact O-N 3.33Å; M371-L373 VanDerWaalsContact C-N 3.3Å; M371-L373 PolarHBondContact O-N 3.07Å; L373-F375 VanDerWaalsContact C-N 3.32Å; L373-F375 PolarHBondContact O-N 3.1Å; L373-L376 HydrophobicContact CD2-CD1 4.08Å; L373-L376 WeakPolarHBondContact O-CB 3.46Å; L373-L376 PolarHBondContact O-N 3.35Å
374	I	95.1	Very high	91.2	Very high	92 Å²	92	43.3 Å²	43.3	47%	0.472	23%	0.225	S	C	.	.	H	α-helix	trans	-63	-41.3	175.5	-68.4	165.7	0	0	0	110.5	L370 M371 L376 C377	L370-I374 HydrophobicContact CG-CD1 4.42Å; L370-I374 WeakPolarHBondContact O-CG1 3.37Å; L370-I374 PolarHBondContact O-N 3.18Å; M371-I374 PolarHBondContact O-N 2.65Å; M371-I374 VanDerWaalsContact O-N 3.15Å; M371-I374 HydrophobicContact SD-CD1 4.15Å; I374-L376 VanDerWaalsContact C-N 3.26Å; I374-L376 PolarHBondContact O-N 3.13Å; I374-C377 VanDerWaalsContact O-CB 3.26Å; I374-C377 WeakPolarHBondContact O-CB 3.31Å; I374-C377 PolarHBondContact O-N 3.05Å; I374-C377 VanDerWaalsContact O-N 3.1Å
375	F	93.6	Very high	91.4	Very high	24 Å²	24	43.3 Å²	43.3	11%	0.105	23%	0.225	C	C	.	.	H	α-helix	trans	-70.6	-18.8	179.6	-86.6	-106.3	0	0	0	113.5	L128 L129 P132 A133 A136 M371 G372 L373 C377 V378 L384	L128-F375 WeakPolarHBondContact O-CE2 3.42Å; L128-F375 WeakPolarHBondContact O-CZ 3.49Å; L129-F375 HydrophobicContact CB-CZ 4.49Å; P132-F375 HydrophobicContact CB-CB 4.42Å; P132-F375 HydrophobicContact CB-CD2 3.54Å; P132-F375 HydrophobicContact CB-CE2 3.87Å; P132-F375 HydrophobicContact CB-CG 3.92Å; P132-F375 HydrophobicContact CG-CE2 4.46Å; A133-F375 HydrophobicContact CB-CD1 3.8Å; A133-F375 HydrophobicContact CB-CE1 3.89Å; A136-F375 HydrophobicContact CB-CB 3.76Å; M371-F375 HydrophobicContact CE-CD2 4.41Å; M371-F375 HydrophobicContact CE-CE2 3.88Å; M371-F375 WeakPolarHBondContact O-CD2 3.49Å; M371-F375 PolarHBondContact O-N 3.39Å; M371-F375 VanDerWaalsContact O-N 3.07Å; G372-F375 PolarHBondContact O-N 3.06Å; L373-F375 VanDerWaalsContact C-N 3.32Å; L373-F375 PolarHBondContact O-N 3.1Å; F375-C377 PolarHBondContact O-N 3.32Å; F375-V378 WeakPolarHBondContact O-CB 3.29Å; F375-V378 WeakPolarHBondContact O-CG2 3.48Å; F375-V378 PolarHBondContact O-N 3.45Å; F375-L384 HydrophobicContact CB-CD2 4.31Å; F375-L384 HydrophobicContact CD1-CD2 3.62Å; F375-L384 HydrophobicContact CE1-CD2 4.49Å; F375-L384 HydrophobicContact CG-CD2 4.46Å
376	L	94.2	Very high	91.3	Very high	9 Å²	9	44 Å²	44	5%	0.047	23%	0.229	C	C	.	.	T	Hydrogen-bonded Turn	trans	-66.3	-18	169.5	-67.7	-179.6	0	0	0	113.4	A136 L140 R162 A165 A166 I169 G372 L373 I374 V378	A136-L376 HydrophobicContact CB-CD2 4.14Å; L140-L376 HydrophobicContact CD1-CD2 4.2Å; L140-L376 HydrophobicContact CD2-CD2 3.91Å; L140-L376 HydrophobicContact CG-CD2 3.73Å; R162-L376 WeakPolarHBondContact CD-O 3.38Å; R162-L376 PolarHBondContact NE-O 3.17Å; A165-L376 HydrophobicContact CB-CD1 4.17Å; A165-L376 HydrophobicContact CB-CD2 3.97Å; A166-L376 HydrophobicContact CB-CD1 3.73Å; I169-L376 HydrophobicContact CD1-CD1 4.08Å; I169-L376 HydrophobicContact CD1-CG 4.35Å; G372-L376 PolarHBondContact O-N 3.04Å; L373-L376 HydrophobicContact CD2-CD1 4.08Å; L373-L376 WeakPolarHBondContact O-CB 3.46Å; L373-L376 PolarHBondContact O-N 3.35Å; I374-L376 VanDerWaalsContact C-N 3.26Å; I374-L376 PolarHBondContact O-N 3.13Å; L376-V378 PolarHBondContact O-N 3.3Å
377	C	91.3	Very high	91.1	Very high	102 Å²	102	41.4 Å²	41.4	69%	0.689	21%	0.214	S	C	*	.	T	Hydrogen-bonded Turn	trans	-71.6	-13.8	174.1	-61	0	0	0	0	112.9	I374 F375	I374-C377 VanDerWaalsContact O-CB 3.26Å; I374-C377 WeakPolarHBondContact O-CB 3.31Å; I374-C377 PolarHBondContact O-N 3.05Å; I374-C377 VanDerWaalsContact O-N 3.1Å; F375-C377 PolarHBondContact O-N 3.32Å
378	V	90.6	Very high	91.1	Very high	27 Å²	27	38.7 Å²	38.7	16%	0.164	20%	0.202	C	C	.	.			trans	-71.6	129.3	172.8	-178	0	0	0	0	108.8	R162 F375 L376 Q383 L384 Y387	R162-V378 PolarHBondContact NH2-O 2.88Å; F375-V378 WeakPolarHBondContact O-CB 3.29Å; F375-V378 WeakPolarHBondContact O-CG2 3.48Å; F375-V378 PolarHBondContact O-N 3.45Å; L376-V378 PolarHBondContact O-N 3.3Å; V378-Q383 HydrophobicContact CG1-CB 4.35Å; V378-Q383 HydrophobicContact CG1-CG 4.27Å; V378-L384 HydrophobicContact CB-CD1 4.42Å; V378-L384 HydrophobicContact CB-CD2 3.78Å; V378-L384 HydrophobicContact CB-CG 4.03Å; V378-L384 HydrophobicContact CG1-CD2 4.01Å; V378-L384 HydrophobicContact CG1-CG 3.93Å; V378-L384 HydrophobicContact CG2-CD2 3.83Å; V378-Y387 HydrophobicContact CG1-CE2 4.49Å
379	E	84.5	Confident	91.1	Very high	146 Å²	146	38.7 Å²	38.7	68%	0.682	20%	0.202	S	C	*	.	S	Bend	trans	-72.2	-42.7	-172.2	-54.3	-157.3	154.4	0	0	112.2	Y158 R162	Y158-E379 HydrophobicContact CE2-CB 4.39Å; Y158-E379 WeakPolarHBondContact OH-CG 3.47Å; R162-E379 VanDerWaalsContact NH2-C 3.34Å; R162-E379 PolarHBondContact NH2-O 3.42Å
380	D	87.6	Confident	91.1	Very high	77 Å²	77	38.9 Å²	38.9	41%	0.412	20%	0.203	S	C	.	.			trans	-100.7	126.8	-172.6	-175.7	4.3	0	0	0	112.7	F382 Q383 L384	D380-F382 PolarHBondContact OD1-N 3.05Å; D380-Q383 HydrophobicContact CB-CB 3.93Å; D380-Q383 WeakPolarHBondContact O-CB 3.4Å; D380-Q383 PolarHBondContact O-N 3.45Å; D380-L384 PolarHBondContact O-N 2.92Å
381	V	88.9	Confident	90.9	Very high	23 Å²	23	34.2 Å²	34.2	14%	0.139	18%	0.179	C	C	.	.	H	α-helix	trans	-67.8	-34.9	176.6	-175.8	0	0	0	0	111.4	V60 V137 L140 Q383 L384 I385	V60-V381 HydrophobicContact CG1-CG1 4.28Å; V137-V381 HydrophobicContact CB-CG1 4.35Å; V137-V381 HydrophobicContact CG1-CG1 3.83Å; V137-V381 HydrophobicContact CG2-CG1 4.09Å; L140-V381 HydrophobicContact CB-CG2 4.24Å; L140-V381 HydrophobicContact CD1-CG2 3.93Å; V381-Q383 VanDerWaalsContact C-N 3.33Å; V381-L384 WeakPolarHBondContact O-CB 3.34Å; V381-L384 PolarHBondContact O-N 2.92Å; V381-I385 HydrophobicContact CG1-CD1 4.37Å; V381-I385 WeakPolarHBondContact O-CG1 3.14Å; V381-I385 PolarHBondContact O-N 3.4Å
382	F	87.9	Confident	90.8	Very high	31 Å²	31	33.7 Å²	33.7	14%	0.136	18%	0.175	C	C	.	.	H	α-helix	trans	-70.5	-32.9	178.4	-68.2	-71.3	0	0	0	111.8	V60 K63 G64 D380 L384 I385 N386	V60-F382 HydrophobicContact CG1-CE1 4.27Å; V60-F382 HydrophobicContact CG1-CZ 4.37Å; K63-F382 HydrophobicContact CB-CZ 4.13Å; K63-F382 HydrophobicContact CD-CE2 4Å; K63-F382 HydrophobicContact CD-CZ 3.94Å; K63-F382 HydrophobicContact CG-CE2 4.37Å; K63-F382 HydrophobicContact CG-CZ 3.98Å; G64-F382 VanDerWaalsContact CA-CE1 3.43Å; D380-F382 PolarHBondContact OD1-N 3.05Å; F382-L384 VanDerWaalsContact C-N 3.33Å; F382-L384 PolarHBondContact O-N 3.4Å; F382-I385 HydrophobicContact CD1-CD1 4.06Å; F382-I385 HydrophobicContact CE1-CD1 4.39Å; F382-I385 PolarHBondContact O-N 2.9Å; F382-N386 VanDerWaalsContact O-CG 3.26Å; F382-N386 PolarHBondContact O-N 2.85Å; F382-N386 PolarHBondContact O-OD1 3.01Å
383	Q	90.1	Very high	90.7	Very high	52 Å²	52	33.7 Å²	33.7	24%	0.243	18%	0.175	C	C	.	.	H	α-helix	trans	-60.2	-43.2	170.1	-176.1	173.3	34.5	0	0	111.6	V378 D380 V381 N386 Y387 N445	V378-Q383 HydrophobicContact CG1-CB 4.35Å; V378-Q383 HydrophobicContact CG1-CG 4.27Å; D380-Q383 HydrophobicContact CB-CB 3.93Å; D380-Q383 WeakPolarHBondContact O-CB 3.4Å; D380-Q383 PolarHBondContact O-N 3.45Å; V381-Q383 VanDerWaalsContact C-N 3.33Å; Q383-N386 PolarHBondContact O-N 3.35Å; Q383-Y387 HydrophobicContact CG-CD2 4.3Å; Q383-Y387 HydrophobicContact CG-CE1 4.31Å; Q383-Y387 HydrophobicContact CG-CE2 3.63Å; Q383-Y387 PolarHBondContact NE2-OH 2.9Å; Q383-Y387 WeakPolarHBondContact O-CD2 3.08Å; Q383-Y387 PolarHBondContact O-N 3.31Å; Q383-N445 PolarHBondContact NE2-OD1 3.07Å
384	L	91.6	Very high	90.6	Very high	0 Å²	0	34.2 Å²	34.2	0%	0	18%	0.178	C	C	.	.	H	α-helix	trans	-62.1	-41.9	173.9	-68.2	170.6	0	0	0	112.3	A133 A136 V137 L140 F375 V378 D380 V381 F382 N386 Y387 F388	A133-L384 HydrophobicContact CB-CD2 4.33Å; A136-L384 HydrophobicContact CB-CD1 3.86Å; A136-L384 HydrophobicContact CB-CD2 4.49Å; V137-L384 HydrophobicContact CG2-CB 3.45Å; V137-L384 VanDerWaalsContact CG2-CB 3.45Å; V137-L384 HydrophobicContact CG2-CD1 4.14Å; V137-L384 HydrophobicContact CG2-CG 4.45Å; L140-L384 HydrophobicContact CD1-CD1 3.84Å; F375-L384 HydrophobicContact CB-CD2 4.31Å; F375-L384 HydrophobicContact CD1-CD2 3.62Å; F375-L384 HydrophobicContact CE1-CD2 4.49Å; F375-L384 HydrophobicContact CG-CD2 4.46Å; V378-L384 HydrophobicContact CB-CD1 4.42Å; V378-L384 HydrophobicContact CB-CD2 3.78Å; V378-L384 HydrophobicContact CB-CG 4.03Å; V378-L384 HydrophobicContact CG1-CD2 4.01Å; V378-L384 HydrophobicContact CG1-CG 3.93Å; V378-L384 HydrophobicContact CG2-CD2 3.83Å; D380-L384 PolarHBondContact O-N 2.92Å; V381-L384 WeakPolarHBondContact O-CB 3.34Å; V381-L384 PolarHBondContact O-N 2.92Å; F382-L384 VanDerWaalsContact C-N 3.33Å; F382-L384 PolarHBondContact O-N 3.4Å; L384-N386 VanDerWaalsContact C-N 3.3Å; L384-N386 PolarHBondContact O-N 3.29Å; L384-Y387 HydrophobicContact CD2-CD2 4.39Å; L384-Y387 PolarHBondContact O-N 3.24Å; L384-F388 WeakPolarHBondContact O-CB 3.32Å; L384-F388 PolarHBondContact O-N 2.8Å
385	I	91	Very high	90.5	Very high	0 Å²	0	30.3 Å²	30.3	0%	0	16%	0.158	C	C	.	.	H	α-helix	trans	-61.3	-40.1	175.3	-69.6	169.6	0	0	0	110.7	V60 V137 F240 V381 F382 S389	V60-I385 HydrophobicContact CG1-CD1 3.92Å; V137-I385 HydrophobicContact CG1-CD1 4.31Å; V137-I385 HydrophobicContact CG1-CG1 4.08Å; V137-I385 HydrophobicContact CG2-CG1 3.92Å; F240-I385 HydrophobicContact CB-CG2 3.88Å; F240-I385 HydrophobicContact CD1-CD1 4.2Å; F240-I385 HydrophobicContact CD1-CG1 4.2Å; F240-I385 HydrophobicContact CD2-CG1 4.36Å; F240-I385 HydrophobicContact CD2-CG2 4.36Å; F240-I385 HydrophobicContact CE1-CD1 4.45Å; F240-I385 HydrophobicContact CE1-CG1 4.35Å; F240-I385 HydrophobicContact CG-CG1 4.21Å; F240-I385 HydrophobicContact CG-CG2 4.06Å; V381-I385 HydrophobicContact CG1-CD1 4.37Å; V381-I385 WeakPolarHBondContact O-CG1 3.14Å; V381-I385 PolarHBondContact O-N 3.4Å; F382-I385 HydrophobicContact CD1-CD1 4.06Å; F382-I385 HydrophobicContact CE1-CD1 4.39Å; F382-I385 PolarHBondContact O-N 2.9Å; I385-S389 WeakPolarHBondContact O-CB 3.26Å; I385-S389 PolarHBondContact O-N 3.45Å; I385-S389 PolarHBondContact O-OG 3.12Å
386	N	88.9	Confident	90.4	Very high	17 Å²	17	29.1 Å²	29.1	9%	0.091	15%	0.153	C	C	.	.	H	α-helix	trans	-68.7	-43.5	178.7	-69.7	-7.9	0	0	0	111.8	F382 Q383 L384 F388 S389 F390 D442	F382-N386 VanDerWaalsContact O-CG 3.26Å; F382-N386 PolarHBondContact O-N 2.85Å; F382-N386 PolarHBondContact O-OD1 3.01Å; Q383-N386 PolarHBondContact O-N 3.35Å; L384-N386 VanDerWaalsContact C-N 3.3Å; L384-N386 PolarHBondContact O-N 3.29Å; N386-F388 PolarHBondContact O-N 3.28Å; N386-S389 PolarHBondContact O-N 2.85Å; N386-F390 WeakPolarHBondContact O-CB 3.43Å; N386-F390 PolarHBondContact O-N 3.3Å; N386-D442 PolarHBondContact ND2-OD2 3.42Å
387	Y	87.8	Confident	90.5	Very high	23 Å²	23	29.1 Å²	29.1	9%	0.09	16%	0.155	C	C	.	.	H	α-helix	trans	-54.9	-53.6	172.7	-67.8	-34.7	0	0	0	111	L129 V378 Q383 L384 S389 N445 I448	L129-Y387 WeakPolarHBondContact CD2-O 3.43Å; V378-Y387 HydrophobicContact CG1-CE2 4.49Å; Q383-Y387 HydrophobicContact CG-CD2 4.3Å; Q383-Y387 HydrophobicContact CG-CE1 4.31Å; Q383-Y387 HydrophobicContact CG-CE2 3.63Å; Q383-Y387 PolarHBondContact NE2-OH 2.9Å; Q383-Y387 WeakPolarHBondContact O-CD2 3.08Å; Q383-Y387 PolarHBondContact O-N 3.31Å; L384-Y387 HydrophobicContact CD2-CD2 4.39Å; L384-Y387 PolarHBondContact O-N 3.24Å; Y387-S389 PolarHBondContact O-N 3.42Å; Y387-N445 HydrophobicContact CD1-CB 3.92Å; Y387-N445 HydrophobicContact CE1-CB 3.58Å; Y387-N445 WeakPolarHBondContact CE1-OD1 3.45Å; Y387-N445 PolarHBondContact OH-OD1 3.27Å; Y387-I448 HydrophobicContact CE1-CB 4.15Å; Y387-I448 HydrophobicContact CE1-CD1 4.06Å; Y387-I448 HydrophobicContact CE1-CG2 4.12Å; Y387-I448 WeakPolarHBondContact OH-CD1 3.33Å
388	F	91.5	Very high	90.7	Very high	8 Å²	8	26.3 Å²	26.3	4%	0.035	13%	0.133	C	C	.	.	H	α-helix	trans	-55.5	-53.3	177.5	169.1	-91.9	0	0	0	111.3	I130 A133 F240 L384 N386 F390 S391 Y392	I130-F388 HydrophobicContact CB-CD2 4.44Å; I130-F388 HydrophobicContact CG2-CD2 3.51Å; I130-F388 HydrophobicContact CG2-CE2 3.43Å; I130-F388 VanDerWaalsContact CG2-CE2 3.43Å; I130-F388 WeakPolarHBondContact O-CD2 3.31Å; A133-F388 HydrophobicContact CB-CB 4.32Å; F240-F388 AromaticContact CD2-CD1 3.58Å; F240-F388 HydrophobicContact CD2-CD1 3.58Å; F240-F388 AromaticContact CD2-CE1 3.74Å; F240-F388 HydrophobicContact CD2-CE1 3.74Å; F240-F388 HydrophobicContact CD2-CG 4.34Å; F240-F388 HydrophobicContact CE2-CD1 4.05Å; F240-F388 HydrophobicContact CE2-CE1 4.25Å; F240-F388 HydrophobicContact CE2-CG 4.41Å; L384-F388 WeakPolarHBondContact O-CB 3.32Å; L384-F388 PolarHBondContact O-N 2.8Å; N386-F388 PolarHBondContact O-N 3.28Å; F388-F390 PolarHBondContact O-N 3.12Å; F388-S391 PolarHBondContact O-N 3.01Å; F388-Y392 HydrophobicContact CE1-CD1 4.16Å; F388-Y392 HydrophobicContact CE1-CG 4.1Å; F388-Y392 HydrophobicContact CE2-CD2 4.13Å; F388-Y392 HydrophobicContact CE2-CG 4.24Å; F388-Y392 HydrophobicContact CZ-CD1 4.06Å; F388-Y392 AromaticContact CZ-CD2 3.9Å; F388-Y392 HydrophobicContact CZ-CD2 3.9Å; F388-Y392 HydrophobicContact CZ-CE1 4.48Å; F388-Y392 HydrophobicContact CZ-CE2 4.36Å; F388-Y392 AromaticContact CZ-CG 3.74Å; F388-Y392 HydrophobicContact CZ-CG 3.74Å; F388-Y392 WeakPolarHBondContact O-CB 3.45Å; F388-Y392 PolarHBondContact O-N 3.2Å
389	S	90.8	Very high	90.9	Very high	0 Å²	0	25 Å²	25	0%	0	13%	0.125	C	C	.	.	H	α-helix	trans	-64.4	-46.2	-169.7	-63.6	0	0	0	0	112	I385 N386 Y387 S391 Y392 W393	I385-S389 WeakPolarHBondContact O-CB 3.26Å; I385-S389 PolarHBondContact O-N 3.45Å; I385-S389 PolarHBondContact O-OG 3.12Å; N386-S389 PolarHBondContact O-N 2.85Å; Y387-S389 PolarHBondContact O-N 3.42Å; S389-S391 PolarHBondContact O-N 3.3Å; S389-Y392 PolarHBondContact O-N 2.77Å; S389-W393 WeakPolarHBondContact O-CB 3.23Å; S389-W393 PolarHBondContact O-N 3.03Å
390	F	90.2	Very high	91.4	Very high	6 Å²	6	18.1 Å²	18.1	3%	0.026	9%	0.092	C	C	.	.	H	α-helix	trans	-56.7	-53.7	-179.5	176.5	-90.6	0	0	0	111.6	Y236 N386 F388 L394 V435 L439 I450	Y236-F390 HydrophobicContact CE2-CB 4.25Å; Y236-F390 WeakPolarHBondContact OH-CA 3.46Å; N386-F390 WeakPolarHBondContact O-CB 3.43Å; N386-F390 PolarHBondContact O-N 3.3Å; F388-F390 PolarHBondContact O-N 3.12Å; F390-L394 WeakPolarHBondContact O-CB 3.45Å; F390-L394 PolarHBondContact O-N 3.24Å; F390-L394 VanDerWaalsContact O-N 3.16Å; F390-V435 HydrophobicContact CE2-CB 4.43Å; F390-V435 HydrophobicContact CE2-CG1 3.76Å; F390-V435 WeakPolarHBondContact CE2-O 3.38Å; F390-V435 HydrophobicContact CZ-CG1 3.96Å; F390-L439 HydrophobicContact CE2-CD2 4.2Å; F390-L439 HydrophobicContact CE2-CG 4.37Å; F390-L439 HydrophobicContact CZ-CD2 4.36Å; F390-I450 HydrophobicContact CE1-CD1 4.44Å; F390-I450 HydrophobicContact CE1-CG1 3.8Å; F390-I450 HydrophobicContact CZ-CD1 3.97Å; F390-I450 HydrophobicContact CZ-CG1 3.82Å
391	S	91.3	Very high	91.8	Very high	2 Å²	2	16 Å²	16	1%	0.014	9%	0.086	C	C	.	.	H	α-helix	trans	-70.5	-40.7	-178.5	-67.1	0	0	0	0	112.2	L129 F388 S389 L394 Y395	L129-S391 WeakPolarHBondContact CD2-OG 3.3Å; F388-S391 PolarHBondContact O-N 3.01Å; S389-S391 PolarHBondContact O-N 3.3Å; S391-L394 PolarHBondContact O-N 3.29Å; S391-Y395 WeakPolarHBondContact O-CD2 3.34Å; S391-Y395 PolarHBondContact O-N 3.2Å
392	Y	91.4	Very high	92.1	Very high	14 Å²	14	15 Å²	15	6%	0.055	8%	0.08	C	C	.	.	H	α-helix	trans	-60.7	-51.2	-179.9	-176	-101.9	0	0	0	111.3	I130 D246 F388 S389 L394 Y395 V396	I130-Y392 HydrophobicContact CG2-CD2 4.06Å; D246-Y392 PolarHBondContact OD1-OH 3.39Å; D246-Y392 PolarHBondContact OD2-OH 3.37Å; F388-Y392 HydrophobicContact CE1-CD1 4.16Å; F388-Y392 HydrophobicContact CE1-CG 4.1Å; F388-Y392 HydrophobicContact CE2-CD2 4.13Å; F388-Y392 HydrophobicContact CE2-CG 4.24Å; F388-Y392 HydrophobicContact CZ-CD1 4.06Å; F388-Y392 AromaticContact CZ-CD2 3.9Å; F388-Y392 HydrophobicContact CZ-CD2 3.9Å; F388-Y392 HydrophobicContact CZ-CE1 4.48Å; F388-Y392 HydrophobicContact CZ-CE2 4.36Å; F388-Y392 AromaticContact CZ-CG 3.74Å; F388-Y392 HydrophobicContact CZ-CG 3.74Å; F388-Y392 WeakPolarHBondContact O-CB 3.45Å; F388-Y392 PolarHBondContact O-N 3.2Å; S389-Y392 PolarHBondContact O-N 2.77Å; Y392-L394 PolarHBondContact O-N 3.24Å; Y392-Y395 PolarHBondContact O-N 3.43Å; Y392-V396 HydrophobicContact CD1-CG2 4.15Å; Y392-V396 HydrophobicContact CD2-CG2 4.45Å; Y392-V396 HydrophobicContact CE1-CG2 3.87Å; Y392-V396 HydrophobicContact CE2-CG2 4.19Å; Y392-V396 HydrophobicContact CG-CG2 4.43Å; Y392-V396 VanDerWaalsContact O-CG2 3.27Å; Y392-V396 WeakPolarHBondContact O-CG2 3.41Å; Y392-V396 PolarHBondContact O-N 3.49Å
393	W	90.9	Very high	92.4	Very high	0 Å²	0	13.7 Å²	13.7	0%	0	7%	0.074	C	C	.	.	H	α-helix	trans	-69.6	-31.6	-178.7	-60.8	122.2	0	0	0	113.4	F85 L239 S389 Y395 V396 G397 Y427 L434	F85-W393 HydrophobicContact CE1-CD2 4.32Å; F85-W393 AromaticContact CE1-CE3 3.8Å; F85-W393 HydrophobicContact CE1-CE3 3.8Å; F85-W393 HydrophobicContact CE1-CH2 4.49Å; F85-W393 AromaticContact CE1-CZ3 3.88Å; F85-W393 HydrophobicContact CE1-CZ3 3.88Å; F85-W393 HydrophobicContact CZ-CE3 4.3Å; L239-W393 HydrophobicContact CB-CH2 4.43Å; L239-W393 HydrophobicContact CB-CZ2 3.52Å; L239-W393 HydrophobicContact CD1-CZ2 4.42Å; L239-W393 HydrophobicContact CD2-CZ2 4.36Å; L239-W393 HydrophobicContact CG-CZ2 4.32Å; L239-W393 WeakPolarHBondContact O-CZ2 3.42Å; S389-W393 WeakPolarHBondContact O-CB 3.23Å; S389-W393 PolarHBondContact O-N 3.03Å; W393-Y395 VanDerWaalsContact C-N 3.33Å; W393-Y395 PolarHBondContact O-N 2.63Å; W393-V396 HydrophobicContact CE3-CB 4.38Å; W393-G397 PolarHBondContact O-N 3.35Å; W393-Y427 WeakPolarHBondContact CZ3-OH 3.37Å; W393-L434 HydrophobicContact CG-CD1 4.34Å
394	L	92.3	Very high	92.6	Very high	65 Å²	65	12 Å²	12	34%	0.34	7%	0.067	S	C	.	.	H	α-helix	trans	-56.6	-48.5	170.9	176.2	66.6	0	0	0	111.2	F390 S391 Y392 L398 V435	F390-L394 WeakPolarHBondContact O-CB 3.45Å; F390-L394 PolarHBondContact O-N 3.24Å; F390-L394 VanDerWaalsContact O-N 3.16Å; S391-L394 PolarHBondContact O-N 3.29Å; Y392-L394 PolarHBondContact O-N 3.24Å; L394-L398 WeakPolarHBondContact O-CB 3.07Å; L394-L398 PolarHBondContact O-N 3.32Å; L394-V435 HydrophobicContact CB-CG2 3.9Å; L394-V435 HydrophobicContact CD1-CG1 4.19Å; L394-V435 HydrophobicContact CD1-CG2 3.97Å
395	Y	93.3	Very high	92.8	Very high	10 Å²	10	17.3 Å²	17.3	4%	0.039	9%	0.088	C	C	.	.	H	α-helix	trans	-79.2	-31.3	-175.8	-73.9	-55.8	0	0	0	114.4	I110 I121 R122 T125 I130 S391 Y392 W393 G397 L398 S399	I110-Y395 HydrophobicContact CD1-CD1 4.42Å; I121-Y395 WeakPolarHBondContact CG2-OH 3.45Å; I121-Y395 PolarHBondContact O-OH 2.98Å; R122-Y395 HydrophobicContact CB-CD1 3.93Å; R122-Y395 HydrophobicContact CB-CE1 3.98Å; R122-Y395 HydrophobicContact CB-CG 4.46Å; R122-Y395 VanDerWaalsContact CD-CD1 3.4Å; R122-Y395 HydrophobicContact CG-CD1 4.28Å; R122-Y395 HydrophobicContact CG-CG 4.37Å; T125-Y395 HydrophobicContact CG2-CE2 3.69Å; T125-Y395 PolarHBondContact OG1-OH 3.04Å; I130-Y395 HydrophobicContact CD1-CD2 4Å; I130-Y395 HydrophobicContact CD1-CE2 4.43Å; S391-Y395 WeakPolarHBondContact O-CD2 3.34Å; S391-Y395 PolarHBondContact O-N 3.2Å; Y392-Y395 PolarHBondContact O-N 3.43Å; W393-Y395 VanDerWaalsContact C-N 3.33Å; W393-Y395 PolarHBondContact O-N 2.63Å; Y395-G397 VanDerWaalsContact C-N 3.35Å; Y395-L398 HydrophobicContact CD1-CD2 4.25Å; Y395-L398 PolarHBondContact O-N 3.35Å; Y395-S399 PolarHBondContact O-N 3.47Å; Y395-S399 PolarHBondContact O-OG 3.18Å
396	V	93.1	Very high	92.9	Very high	0 Å²	0	17.4 Å²	17.4	0%	0	9%	0.088	C	C	.	.	H	α-helix	trans	-66	-43.9	170.6	177.8	0	0	0	0	109.4	Y93 W245 Y392 W393 L398 S399 V400 Y427	Y93-V396 HydrophobicContact CE2-CG1 3.64Å; Y93-V396 WeakPolarHBondContact OH-CA 3.41Å; W245-V396 HydrophobicContact CH2-CG1 3.97Å; W245-V396 HydrophobicContact CZ2-CG1 4.01Å; Y392-V396 HydrophobicContact CD1-CG2 4.15Å; Y392-V396 HydrophobicContact CD2-CG2 4.45Å; Y392-V396 HydrophobicContact CE1-CG2 3.87Å; Y392-V396 HydrophobicContact CE2-CG2 4.19Å; Y392-V396 HydrophobicContact CG-CG2 4.43Å; Y392-V396 VanDerWaalsContact O-CG2 3.27Å; Y392-V396 WeakPolarHBondContact O-CG2 3.41Å; Y392-V396 PolarHBondContact O-N 3.49Å; W393-V396 HydrophobicContact CE3-CB 4.38Å; V396-L398 VanDerWaalsContact C-N 3.34Å; V396-L398 PolarHBondContact O-N 2.98Å; V396-S399 WeakPolarHBondContact O-CB 3.32Å; V396-S399 PolarHBondContact O-N 2.92Å; V396-V400 WeakPolarHBondContact O-CG2 3.37Å; V396-V400 PolarHBondContact O-N 3.03Å; V396-Y427 HydrophobicContact CG1-CE1 3.87Å; V396-Y427 WeakPolarHBondContact CG1-OH 3.38Å
397	G	94.8	Very high	93.1	Very high	9 Å²	9	17.9 Å²	17.9	9%	0.093	9%	0.089	C	C	.	.	H	α-helix	trans	-57.2	-43.6	170.9	0	0	0	0	0	112.8	W393 Y395 S399 V400 A401	W393-G397 PolarHBondContact O-N 3.35Å; Y395-G397 VanDerWaalsContact C-N 3.35Å; G397-S399 VanDerWaalsContact C-N 3.35Å; G397-S399 PolarHBondContact O-N 3.12Å; G397-V400 PolarHBondContact O-N 2.91Å; G397-A401 WeakPolarHBondContact O-CB 3.3Å; G397-A401 PolarHBondContact O-N 3.34Å
398	L	95.3	Very high	93.4	Very high	43 Å²	43	23.5 Å²	23.5	23%	0.225	11%	0.114	C	C	.	.	H	α-helix	trans	-62.8	-40.1	175.6	-175.4	62.4	0	0	0	112	I110 F114 L118 L394 Y395 V396 V400 A401 G402	I110-L398 HydrophobicContact CD1-CB 4.45Å; I110-L398 HydrophobicContact CD1-CD2 4.03Å; I110-L398 HydrophobicContact CD1-CG 4.28Å; I110-L398 HydrophobicContact CG1-CD2 4.4Å; I110-L398 HydrophobicContact CG1-CG 4.35Å; I110-L398 HydrophobicContact CG2-CD2 4.39Å; F114-L398 HydrophobicContact CD2-CD1 4.18Å; F114-L398 HydrophobicContact CD2-CG 4.34Å; F114-L398 HydrophobicContact CE2-CD1 3.68Å; F114-L398 HydrophobicContact CE2-CG 4.04Å; F114-L398 WeakPolarHBondContact CE2-O 3.41Å; F114-L398 HydrophobicContact CZ-CD1 4.11Å; L118-L398 HydrophobicContact CD1-CD1 4.49Å; L118-L398 HydrophobicContact CD1-CD2 4.25Å; L394-L398 WeakPolarHBondContact O-CB 3.07Å; L394-L398 PolarHBondContact O-N 3.32Å; Y395-L398 HydrophobicContact CD1-CD2 4.25Å; Y395-L398 PolarHBondContact O-N 3.35Å; V396-L398 VanDerWaalsContact C-N 3.34Å; V396-L398 PolarHBondContact O-N 2.98Å; L398-V400 PolarHBondContact O-N 3.31Å; L398-A401 WeakPolarHBondContact O-CB 3.41Å; L398-A401 PolarHBondContact O-N 2.95Å; L398-G402 PolarHBondContact O-N 3.31Å
399	S	94.8	Very high	93.5	Very high	0 Å²	0	26.3 Å²	26.3	0%	0	13%	0.132	C	C	.	.	H	α-helix	trans	-62.8	-42.3	176.5	-56.5	0	0	0	0	111.5	Y93 Y395 V396 G397 G402 L403	Y93-S399 WeakPolarHBondContact OH-CB 3.46Å; Y93-S399 PolarHBondContact OH-OG 3.44Å; Y395-S399 PolarHBondContact O-N 3.47Å; Y395-S399 PolarHBondContact O-OG 3.18Å; V396-S399 WeakPolarHBondContact O-CB 3.32Å; V396-S399 PolarHBondContact O-N 2.92Å; G397-S399 VanDerWaalsContact C-N 3.35Å; G397-S399 PolarHBondContact O-N 3.12Å; S399-G402 WeakPolarHBondContact O-CA 3.3Å; S399-G402 PolarHBondContact O-N 3.03Å; S399-G402 VanDerWaalsContact O-N 3.16Å; S399-L403 PolarHBondContact O-N 3.46Å; S399-L403 VanDerWaalsContact O-N 3.1Å
400	V	95.7	Very high	93.6	Very high	0 Å²	0	30 Å²	30	0%	0	15%	0.149	C	C	.	.	H	α-helix	trans	-69.4	-35	175.1	-179.8	0	0	0	0	111.9	C92 Y93 V396 G397 L398 G402 L403 I404 P424 Y427	C92-V400 HydrophobicContact CB-CG1 4.02Å; C92-V400 HydrophobicContact CB-CG2 3.88Å; Y93-V400 HydrophobicContact CD2-CG2 4.1Å; Y93-V400 HydrophobicContact CE2-CG2 3.88Å; V396-V400 WeakPolarHBondContact O-CG2 3.37Å; V396-V400 PolarHBondContact O-N 3.03Å; G397-V400 PolarHBondContact O-N 2.91Å; L398-V400 PolarHBondContact O-N 3.31Å; V400-G402 PolarHBondContact O-N 3.41Å; V400-L403 VanDerWaalsContact O-CB 3.25Å; V400-L403 WeakPolarHBondContact O-CB 3.43Å; V400-L403 PolarHBondContact O-N 2.99Å; V400-L403 VanDerWaalsContact O-N 3.08Å; V400-I404 PolarHBondContact O-N 3.18Å; V400-P424 HydrophobicContact CG1-CB 3.47Å; V400-P424 VanDerWaalsContact CG1-CB 3.47Å; V400-Y427 HydrophobicContact CB-CD1 3.93Å; V400-Y427 HydrophobicContact CB-CE1 4.44Å; V400-Y427 HydrophobicContact CG1-CD1 4.03Å; V400-Y427 HydrophobicContact CG2-CD1 3.62Å; V400-Y427 HydrophobicContact CG2-CE1 3.81Å
401	A	96.2	Very high	93.5	Very high	34 Å²	34	33.3 Å²	33.3	28%	0.281	17%	0.171	S	C	.	.	H	α-helix	trans	-62.1	-36.2	169.8	0	0	0	0	0	111.3	F114 G397 L398 L403 I404 Y405	F114-A401 HydrophobicContact CZ-CB 4.47Å; G397-A401 WeakPolarHBondContact O-CB 3.3Å; G397-A401 PolarHBondContact O-N 3.34Å; L398-A401 WeakPolarHBondContact O-CB 3.41Å; L398-A401 PolarHBondContact O-N 2.95Å; A401-L403 VanDerWaalsContact C-N 3.3Å; A401-L403 PolarHBondContact O-N 3.47Å; A401-I404 PolarHBondContact O-N 2.97Å; A401-Y405 PolarHBondContact O-N 3.01Å
402	G	94.6	Very high	93.5	Very high	1 Å²	1	40.7 Å²	40.7	1%	0.01	21%	0.21	C	C	.	.	H	α-helix	trans	-59.4	-37.6	170.7	0	0	0	0	0	112.8	F114 L398 S399 V400 Y405 L406	F114-G402 VanDerWaalsContact CE2-CA 3.5Å; L398-G402 PolarHBondContact O-N 3.31Å; S399-G402 WeakPolarHBondContact O-CA 3.3Å; S399-G402 PolarHBondContact O-N 3.03Å; S399-G402 VanDerWaalsContact O-N 3.16Å; V400-G402 PolarHBondContact O-N 3.41Å; G402-Y405 PolarHBondContact O-N 2.96Å; G402-L406 WeakPolarHBondContact O-CB 3.48Å; G402-L406 VanDerWaalsContact O-CG 3.3Å; G402-L406 WeakPolarHBondContact O-CG 3.28Å; G402-L406 PolarHBondContact O-N 3.22Å
403	L	94.6	Very high	93.4	Very high	3 Å²	3	43.1 Å²	43.1	2%	0.016	22%	0.219	C	C	.	.	H	α-helix	trans	-60.7	-47.3	172.8	-178.9	64.7	0	0	0	111.7	C92 E95 L96 S399 V400 A401 Y405 L406 R407 P424	C92-L403 HydrophobicContact CB-CD2 4.25Å; E95-L403 HydrophobicContact CB-CD2 4.37Å; E95-L403 HydrophobicContact CG-CD1 3.73Å; E95-L403 HydrophobicContact CG-CD2 4.24Å; E95-L403 WeakPolarHBondContact OE1-CD1 3.49Å; L96-L403 HydrophobicContact CD1-CB 4.21Å; L96-L403 HydrophobicContact CD2-CB 3.79Å; L96-L403 HydrophobicContact CD2-CD1 3.69Å; L96-L403 HydrophobicContact CD2-CG 4.3Å; L96-L403 HydrophobicContact CG-CB 3.98Å; L96-L403 HydrophobicContact CG-CD1 3.95Å; L96-L403 HydrophobicContact CG-CD2 4.48Å; L96-L403 HydrophobicContact CG-CG 4.35Å; S399-L403 PolarHBondContact O-N 3.46Å; S399-L403 VanDerWaalsContact O-N 3.1Å; V400-L403 VanDerWaalsContact O-CB 3.25Å; V400-L403 WeakPolarHBondContact O-CB 3.43Å; V400-L403 PolarHBondContact O-N 2.99Å; V400-L403 VanDerWaalsContact O-N 3.08Å; A401-L403 VanDerWaalsContact C-N 3.3Å; A401-L403 PolarHBondContact O-N 3.47Å; L403-Y405 VanDerWaalsContact C-N 3.33Å; L403-L406 PolarHBondContact O-N 3.29Å; L403-R407 VanDerWaalsContact O-CG 3.26Å; L403-R407 WeakPolarHBondContact O-CG 3.41Å; L403-R407 PolarHBondContact O-N 2.99Å; L403-P424 HydrophobicContact CD2-CB 4.34Å
404	I	95.5	Very high	93.4	Very high	18 Å²	18	49.9 Å²	49.9	9%	0.092	25%	0.251	C	S	.	.	H	α-helix	trans	-62.2	-44.3	177.2	-59.1	175.4	0	0	0	109.9	V400 A401 L406 R407 F408 P424 F425	V400-I404 PolarHBondContact O-N 3.18Å; A401-I404 PolarHBondContact O-N 2.97Å; I404-L406 PolarHBondContact O-N 3.07Å; I404-R407 VanDerWaalsContact O-CB 3.31Å; I404-R407 WeakPolarHBondContact O-CB 3.26Å; I404-R407 PolarHBondContact O-N 3.05Å; I404-F408 HydrophobicContact CG2-CD2 3.99Å; I404-F408 HydrophobicContact CG2-CE2 3.58Å; I404-F408 WeakPolarHBondContact O-CD2 3.5Å; I404-F408 PolarHBondContact O-N 2.88Å; I404-P424 HydrophobicContact CD1-CB 4.03Å; I404-P424 HydrophobicContact CG1-CB 3.81Å; I404-P424 HydrophobicContact CG1-CG 4.17Å; I404-F425 HydrophobicContact CD1-CD1 3.96Å; I404-F425 HydrophobicContact CD1-CE1 4.06Å; I404-F425 HydrophobicContact CD1-CG 4.22Å; I404-F425 HydrophobicContact CD1-CZ 4.41Å; I404-F425 HydrophobicContact CG2-CE1 4.31Å; I404-F425 HydrophobicContact CG2-CE2 4.48Å; I404-F425 HydrophobicContact CG2-CZ 3.94Å
405	Y	95.3	Very high	93.3	Very high	110 Å²	110	48.1 Å²	48.1	43%	0.431	24%	0.24	S	C	.	.	H	α-helix	trans	-58.6	-49.2	177.1	175.4	-102.9	0	0	0	112	S113 F114 A401 G402 L403 R407 F408 T409	S113-Y405 WeakPolarHBondContact O-CD1 3.24Å; S113-Y405 WeakPolarHBondContact O-CE1 3.38Å; F114-Y405 HydrophobicContact CE1-CG 4.26Å; A401-Y405 PolarHBondContact O-N 3.01Å; G402-Y405 PolarHBondContact O-N 2.96Å; L403-Y405 VanDerWaalsContact C-N 3.33Å; Y405-R407 PolarHBondContact O-N 3.32Å; Y405-F408 PolarHBondContact O-N 3.4Å; Y405-T409 HydrophobicContact CD1-CG2 4.4Å; Y405-T409 HydrophobicContact CD2-CG2 3.92Å; Y405-T409 HydrophobicContact CE1-CG2 3.95Å; Y405-T409 HydrophobicContact CE2-CG2 3.42Å; Y405-T409 VanDerWaalsContact CE2-CG2 3.42Å; Y405-T409 HydrophobicContact CG-CG2 4.4Å; Y405-T409 VanDerWaalsContact CZ-CG2 3.46Å; Y405-T409 PolarHBondContact O-N 3.49Å; Y405-T409 PolarHBondContact O-OG1 3.14Å
406	L	93.5	Very high	93.1	Very high	3 Å²	3	49.7 Å²	49.7	2%	0.016	25%	0.251	C	S	.	.	H	α-helix	trans	-62.6	-28.9	177.8	-71.9	172.3	0	0	0	112.6	I100 G402 L403 I404 F408 Q410 R415	I100-L406 HydrophobicContact CD1-CD1 3.98Å; G402-L406 WeakPolarHBondContact O-CB 3.48Å; G402-L406 VanDerWaalsContact O-CG 3.3Å; G402-L406 WeakPolarHBondContact O-CG 3.28Å; G402-L406 PolarHBondContact O-N 3.22Å; L403-L406 PolarHBondContact O-N 3.29Å; I404-L406 PolarHBondContact O-N 3.07Å; L406-F408 VanDerWaalsContact C-N 3.29Å; L406-F408 PolarHBondContact O-N 2.95Å; L406-Q410 CarbonylContact O-C 3.43Å; L406-Q410 VanDerWaalsContact O-C 3.23Å; L406-Q410 WeakPolarHBondContact O-CA 3.34Å; L406-Q410 PolarHBondContact O-N 3.48Å; L406-R415 PolarHBondContact O-NH2 3.37Å
407	R	92.5	Very high	92.9	Very high	26 Å²	26	51 Å²	51	10%	0.098	26%	0.259	C	S	.	.	H	α-helix	trans	-63.1	-36	173.5	-74.6	-84.7	-168.4	-179.5	15.5	112.4	E95 L403 I404 Y405 K418 L419 L421	E95-R407 IonicContact OE1-CZ 2.95Å; E95-R407 IonicContact OE1-NE 2.93Å; E95-R407 PolarHBondContact OE1-NE 3.43Å; E95-R407 IonicContact OE1-NH1 3.91Å; E95-R407 IonicContact OE1-NH2 2.87Å; E95-R407 PolarHBondContact OE1-NH2 2.83Å; E95-R407 IonicContact OE2-CZ 3.97Å; E95-R407 IonicContact OE2-NH2 2.64Å; E95-R407 PolarHBondContact OE2-NH2 2.94Å; L403-R407 VanDerWaalsContact O-CG 3.26Å; L403-R407 WeakPolarHBondContact O-CG 3.41Å; L403-R407 PolarHBondContact O-N 2.99Å; I404-R407 VanDerWaalsContact O-CB 3.31Å; I404-R407 WeakPolarHBondContact O-CB 3.26Å; I404-R407 PolarHBondContact O-N 3.05Å; Y405-R407 PolarHBondContact O-N 3.32Å; R407-K418 VanDerWaalsContact NH2-CG 3.3Å; R407-L419 PolarHBondContact NH2-O 3.23Å; R407-L421 HydrophobicContact CB-CD2 4.28Å; R407-L421 HydrophobicContact CG-CD2 3.95Å
408	F	93.3	Very high	92.6	Very high	141 Å²	141	58.1 Å²	58.1	62%	0.618	29%	0.288	S	S	*	.	H	α-helix	trans	-87.3	-40.7	-179.8	-69.5	-67.7	0	0	0	112.9	I404 Y405 L406	I404-F408 HydrophobicContact CG2-CD2 3.99Å; I404-F408 HydrophobicContact CG2-CE2 3.58Å; I404-F408 WeakPolarHBondContact O-CD2 3.5Å; I404-F408 PolarHBondContact O-N 2.88Å; Y405-F408 PolarHBondContact O-N 3.4Å; L406-F408 VanDerWaalsContact C-N 3.29Å; L406-F408 PolarHBondContact O-N 2.95Å
409	T	93.8	Very high	92.4	Very high	67 Å²	67	57.8 Å²	57.8	41%	0.411	29%	0.286	S	S	.	.	H	α-helix	trans	-84.5	-31.8	-175.9	55.4	0	0	0	0	113.8	Y405	Y405-T409 HydrophobicContact CD1-CG2 4.4Å; Y405-T409 HydrophobicContact CD2-CG2 3.92Å; Y405-T409 HydrophobicContact CE1-CG2 3.95Å; Y405-T409 HydrophobicContact CE2-CG2 3.42Å; Y405-T409 VanDerWaalsContact CE2-CG2 3.42Å; Y405-T409 HydrophobicContact CG-CG2 4.4Å; Y405-T409 VanDerWaalsContact CZ-CG2 3.46Å; Y405-T409 PolarHBondContact O-N 3.49Å; Y405-T409 PolarHBondContact O-OG1 3.14Å
410	Q	92.6	Very high	92.4	Very high	78 Å²	78	61.3 Å²	61.3	36%	0.364	31%	0.31	S	S	.	.			trans	-128.6	70.2	179.9	-62	-179.9	8.9	0	0	110.1	L406 D412 R413 R415	L406-Q410 CarbonylContact O-C 3.43Å; L406-Q410 VanDerWaalsContact O-C 3.23Å; L406-Q410 WeakPolarHBondContact O-CA 3.34Å; L406-Q410 PolarHBondContact O-N 3.48Å; Q410-D412 VanDerWaalsContact C-N 3.33Å; Q410-D412 PolarHBondContact O-N 3.47Å; Q410-R413 HydrophobicContact CB-CB 4.35Å; Q410-R415 PolarHBondContact O-NH2 3.27Å
411	P	89.7	Confident	92.2	Very high	76 Å²	76	64.1 Å²	64.1	49%	0.494	33%	0.325	S	S	.	.	T	Hydrogen-bonded Turn	trans	-65.1	-36.9	-176	25.6	-33.4	0	0	0	112.4	R413 R415	P411-R413 VanDerWaalsContact C-N 3.3Å; P411-R413 PolarHBondContact O-N 2.84Å; P411-R415 PolarHBondContact O-NH1 2.91Å; P411-R415 VanDerWaalsContact O-NH1 3.12Å
412	D	90	Very high	92.1	Very high	156 Å²	156	68.3 Å²	68.3	83%	0.834	34%	0.337	S	S	*	.	T	Hydrogen-bonded Turn	trans	-83.5	0.5	-173.6	-57.6	-43.1	0	0	0	114.4	Q410 H414	Q410-D412 VanDerWaalsContact C-N 3.33Å; Q410-D412 PolarHBondContact O-N 3.47Å; D412-H414 PolarHBondContact O-N 2.7Å
413	R	90.6	Very high	92.1	Very high	65 Å²	65	71 Å²	71	25%	0.245	35%	0.349	C	S	.	.	S	Bend	trans	-60.1	134	176.3	-169	171	-174.6	135.4	-1	109.8	T99 E112 Q410 P411 R415	T99-R413 HydrophobicContact CG2-CG 4.09Å; E112-R413 IonicContact OE1-CZ 3.4Å; E112-R413 IonicContact OE1-NH1 3Å; E112-R413 PolarHBondContact OE1-NH1 2.87Å; E112-R413 IonicContact OE1-NH2 2.95Å; E112-R413 PolarHBondContact OE1-NH2 3.03Å; Q410-R413 HydrophobicContact CB-CB 4.35Å; P411-R413 VanDerWaalsContact C-N 3.3Å; P411-R413 PolarHBondContact O-N 2.84Å; R413-R415 PolarHBondContact O-N 3.4Å
414	H	89.5	Confident	92.1	Very high	142 Å²	142	71 Å²	71	66%	0.657	35%	0.349	S	S	*	.			trans	-61.9	122	177.1	-172.7	68.2	0	0	0	110.2	D412	D412-H414 PolarHBondContact O-N 2.7Å
415	R	91	Very high	92.1	Very high	29 Å²	29	75.1 Å²	75.1	11%	0.109	37%	0.366	C	S	.	.			trans	-128	96.6	-179.2	-68.4	-179	-178.6	108.6	2.7	108.7	E95 T99 L406 Q410 P411 R413 V417	E95-R415 IonicContact OE1-NE 3.91Å; T99-R415 HydrophobicContact CG2-CG 3.99Å; L406-R415 PolarHBondContact O-NH2 3.37Å; Q410-R415 PolarHBondContact O-NH2 3.27Å; P411-R415 PolarHBondContact O-NH1 2.91Å; P411-R415 VanDerWaalsContact O-NH1 3.12Å; R413-R415 PolarHBondContact O-N 3.4Å; R415-V417 PolarHBondContact O-N 3.38Å
416	P	88.3	Confident	92.1	Very high	43 Å²	43	71.9 Å²	71.9	28%	0.279	36%	0.358	S	S	.	.	S	Bend	trans	-58.8	-37.9	179.1	-25.1	34.4	0	0	0	112.2	E259	E259-P416 HydrophobicContact CB-CB 3.91Å; E259-P416 VanDerWaalsContact CD-CG 3.49Å; E259-P416 HydrophobicContact CG-CB 3.63Å; E259-P416 HydrophobicContact CG-CG 3.72Å; E259-P416 WeakPolarHBondContact OE1-CG 3.19Å
417	V	88.6	Confident	92.1	Very high	27 Å²	27	71.8 Å²	71.8	16%	0.164	36%	0.357	C	S	.	.	S	Bend	trans	-111.9	123.8	173.6	-177.5	0	0	0	0	108.2	E95 T98 P263 R415	E95-V417 VanDerWaalsContact CG-O 3.31Å; E95-V417 WeakPolarHBondContact CG-O 3.45Å; T98-V417 HydrophobicContact CG2-CG2 3.91Å; P263-V417 HydrophobicContact CG-CG2 3.58Å; R415-V417 PolarHBondContact O-N 3.38Å
418	K	90.4	Very high	92.2	Very high	159 Å²	159	71.5 Å²	71.5	69%	0.691	36%	0.359	S	S	*	.			trans	-127.5	103.3	-178.3	162	153	-169.6	-179.9	0	109	R407	R407-K418 VanDerWaalsContact NH2-CG 3.3Å
419	L	90.3	Very high	92.3	Very high	35 Å²	35	70.6 Å²	70.6	18%	0.183	36%	0.36	C	S	.	.			trans	-83.3	156.8	174.6	-65.3	169.1	0	0	0	111	L91 E95 R407	L91-L419 HydrophobicContact CB-CD1 3.72Å; L91-L419 WeakPolarHBondContact O-CD1 3.26Å; E95-L419 HydrophobicContact CB-CD1 4.31Å; E95-L419 WeakPolarHBondContact OE2-CB 3.32Å; E95-L419 PolarHBondContact OE2-N 3.11Å; R407-L419 PolarHBondContact NH2-O 3.23Å
420	S	93.5	Very high	92.2	Very high	74 Å²	74	69.7 Å²	69.7	52%	0.517	36%	0.356	S	S	.	.			trans	-63.1	139.5	167	177.4	0	0	0	0	109.7	F422 F423 P424	S420-F422 PolarHBondContact O-N 2.7Å; S420-F422 PolarHBondContact OG-N 3.25Å; S420-F423 PolarHBondContact O-N 2.95Å; S420-P424 VanDerWaalsContact O-CD 3.28Å; S420-P424 WeakPolarHBondContact O-CD 3.5Å
421	L	93.4	Very high	92.2	Very high	59 Å²	59	66.2 Å²	66.2	31%	0.309	34%	0.34	S	S	.	.	T	Hydrogen-bonded Turn	trans	-60.2	-17.8	177.6	-72.9	174	0	0	0	113.1	R407 F423 P424 F425	R407-L421 HydrophobicContact CB-CD2 4.28Å; R407-L421 HydrophobicContact CG-CD2 3.95Å; L421-F423 VanDerWaalsContact C-N 3.29Å; L421-F423 PolarHBondContact O-N 2.92Å; L421-P424 HydrophobicContact CD2-CG 4.36Å; L421-P424 WeakPolarHBondContact O-CD 3.45Å; L421-P424 VanDerWaalsContact O-CG 3.3Å; L421-P424 WeakPolarHBondContact O-CG 3.44Å; L421-F425 HydrophobicContact CB-CD2 3.98Å; L421-F425 HydrophobicContact CB-CE2 4.01Å; L421-F425 HydrophobicContact CD1-CE2 4.48Å; L421-F425 WeakPolarHBondContact O-CB 3.11Å; L421-F425 WeakPolarHBondContact O-CD2 3.38Å; L421-F425 PolarHBondContact O-N 3.4Å; L421-F425 VanDerWaalsContact O-N 3.11Å
422	F	94.3	Very high	92.2	Very high	123 Å²	123	67.3 Å²	67.3	54%	0.539	34%	0.342	S	S	.	.	H	α-helix	trans	-51.3	-46.8	173.2	175.6	-100.7	0	0	0	112.6	F88 S420 F425 V426	F88-F422 HydrophobicContact CE2-CE1 4.26Å; S420-F422 PolarHBondContact O-N 2.7Å; S420-F422 PolarHBondContact OG-N 3.25Å; F422-F425 PolarHBondContact O-N 3.2Å; F422-V426 HydrophobicContact CD1-CG2 4.49Å; F422-V426 HydrophobicContact CD2-CG2 4.08Å; F422-V426 HydrophobicContact CE1-CG2 4.16Å; F422-V426 HydrophobicContact CE2-CG2 3.7Å; F422-V426 HydrophobicContact CG-CG2 4.46Å; F422-V426 HydrophobicContact CZ-CG2 3.75Å; F422-V426 VanDerWaalsContact O-CG2 3.28Å; F422-V426 WeakPolarHBondContact O-CG2 3.4Å; F422-V426 PolarHBondContact O-N 3.46Å
423	F	94	Very high	92.3	Very high	57 Å²	57	63.8 Å²	63.8	25%	0.25	32%	0.319	C	S	.	.	H	α-helix	trans	-61.9	-54.4	-177.8	-67	-82.9	0	0	0	113.3	F88 L91 S420 L421 F425 V426 Y427	F88-F423 HydrophobicContact CD1-CD1 4.14Å; F88-F423 HydrophobicContact CD1-CE1 4.37Å; F88-F423 HydrophobicContact CD2-CD1 4.02Å; F88-F423 HydrophobicContact CE1-CD1 4.16Å; F88-F423 HydrophobicContact CE1-CE1 4.03Å; F88-F423 HydrophobicContact CE2-CD1 4.04Å; F88-F423 HydrophobicContact CE2-CE1 4.43Å; F88-F423 HydrophobicContact CG-CD1 4.06Å; F88-F423 HydrophobicContact CZ-CD1 4.12Å; F88-F423 HydrophobicContact CZ-CE1 4.07Å; L91-F423 HydrophobicContact CD1-CD1 4.49Å; L91-F423 HydrophobicContact CD1-CE1 4.38Å; S420-F423 PolarHBondContact O-N 2.95Å; L421-F423 VanDerWaalsContact C-N 3.29Å; L421-F423 PolarHBondContact O-N 2.92Å; F423-F425 VanDerWaalsContact C-N 3.34Å; F423-F425 PolarHBondContact O-N 3.49Å; F423-V426 PolarHBondContact O-N 2.97Å; F423-Y427 WeakPolarHBondContact O-CB 3.47Å; F423-Y427 PolarHBondContact O-N 3.2Å
424	P	95	Very high	92.1	Very high	3 Å²	3	60.9 Å²	60.9	2%	0.019	31%	0.308	C	S	.	.	H	α-helix	trans	-66.4	-33.3	179.4	25.5	-35.1	0	0	0	112.9	C92 V400 L403 I404 S420 L421 Y427 C428	C92-P424 VanDerWaalsContact SG-CA 3.59Å; V400-P424 HydrophobicContact CG1-CB 3.47Å; V400-P424 VanDerWaalsContact CG1-CB 3.47Å; L403-P424 HydrophobicContact CD2-CB 4.34Å; I404-P424 HydrophobicContact CD1-CB 4.03Å; I404-P424 HydrophobicContact CG1-CB 3.81Å; I404-P424 HydrophobicContact CG1-CG 4.17Å; S420-P424 VanDerWaalsContact O-CD 3.28Å; S420-P424 WeakPolarHBondContact O-CD 3.5Å; L421-P424 HydrophobicContact CD2-CG 4.36Å; L421-P424 WeakPolarHBondContact O-CD 3.45Å; L421-P424 VanDerWaalsContact O-CG 3.3Å; L421-P424 WeakPolarHBondContact O-CG 3.44Å; P424-Y427 PolarHBondContact O-N 2.89Å; P424-C428 WeakPolarHBondContact O-CB 3.38Å; P424-C428 PolarHBondContact O-N 2.81Å; P424-C428 PolarHBondContact O-SG 3.24Å
425	F	95.1	Very high	92.1	Very high	104 Å²	104	55 Å²	55	46%	0.456	28%	0.282	S	S	.	.	H	α-helix	trans	-64.5	-47.5	175.3	-86.2	-64.8	0	0	0	112.4	I404 L421 F422 F423 Y427 C428 L429	I404-F425 HydrophobicContact CD1-CD1 3.96Å; I404-F425 HydrophobicContact CD1-CE1 4.06Å; I404-F425 HydrophobicContact CD1-CG 4.22Å; I404-F425 HydrophobicContact CD1-CZ 4.41Å; I404-F425 HydrophobicContact CG2-CE1 4.31Å; I404-F425 HydrophobicContact CG2-CE2 4.48Å; I404-F425 HydrophobicContact CG2-CZ 3.94Å; L421-F425 HydrophobicContact CB-CD2 3.98Å; L421-F425 HydrophobicContact CB-CE2 4.01Å; L421-F425 HydrophobicContact CD1-CE2 4.48Å; L421-F425 WeakPolarHBondContact O-CB 3.11Å; L421-F425 WeakPolarHBondContact O-CD2 3.38Å; L421-F425 PolarHBondContact O-N 3.4Å; L421-F425 VanDerWaalsContact O-N 3.11Å; F422-F425 PolarHBondContact O-N 3.2Å; F423-F425 VanDerWaalsContact C-N 3.34Å; F423-F425 PolarHBondContact O-N 3.49Å; F425-Y427 VanDerWaalsContact C-N 3.3Å; F425-Y427 PolarHBondContact O-N 3.37Å; F425-C428 PolarHBondContact O-N 2.96Å; F425-L429 PolarHBondContact O-N 3.48Å
426	V	95	Very high	92	Very high	42 Å²	42	57.5 Å²	57.5	26%	0.255	30%	0.297	S	S	.	.	H	α-helix	trans	-61.8	-42.7	176.6	172.7	0	0	0	0	110.3	F88 F422 F423 L429 C430	F88-V426 HydrophobicContact CD2-CB 4.25Å; F88-V426 HydrophobicContact CD2-CG1 3.94Å; F88-V426 HydrophobicContact CE2-CB 4.25Å; F88-V426 HydrophobicContact CE2-CG1 3.86Å; F422-V426 HydrophobicContact CD1-CG2 4.49Å; F422-V426 HydrophobicContact CD2-CG2 4.08Å; F422-V426 HydrophobicContact CE1-CG2 4.16Å; F422-V426 HydrophobicContact CE2-CG2 3.7Å; F422-V426 HydrophobicContact CG-CG2 4.46Å; F422-V426 HydrophobicContact CZ-CG2 3.75Å; F422-V426 VanDerWaalsContact O-CG2 3.28Å; F422-V426 WeakPolarHBondContact O-CG2 3.4Å; F422-V426 PolarHBondContact O-N 3.46Å; F423-V426 PolarHBondContact O-N 2.97Å; V426-L429 PolarHBondContact O-N 3.31Å; V426-C430 PolarHBondContact O-N 3.19Å; V426-C430 PolarHBondContact O-SG 3.28Å
427	Y	94.1	Very high	92	Very high	1 Å²	1	56.6 Å²	56.6	0%	0.004	29%	0.291	C	S	.	.	H	α-helix	trans	-63.3	-44	178.9	-170	-92.4	0	0	0	112.8	F85 F88 G89 W393 V396 V400 F423 P424 F425 L429 C430 S431	F85-Y427 HydrophobicContact CD1-CE2 4.02Å; F85-Y427 HydrophobicContact CD2-CD2 4.01Å; F85-Y427 AromaticContact CD2-CE2 3.9Å; F85-Y427 HydrophobicContact CD2-CE2 3.9Å; F85-Y427 AromaticContact CE1-CE2 3.61Å; F85-Y427 HydrophobicContact CE1-CE2 3.61Å; F85-Y427 AromaticContact CE1-CZ 3.88Å; F85-Y427 AromaticContact CE2-CD2 3.67Å; F85-Y427 HydrophobicContact CE2-CD2 3.67Å; F85-Y427 AromaticContact CE2-CE2 3.43Å; F85-Y427 HydrophobicContact CE2-CE2 3.43Å; F85-Y427 VanDerWaalsContact CE2-CE2 3.43Å; F85-Y427 HydrophobicContact CE2-CG 4.38Å; F85-Y427 AromaticContact CE2-CZ 3.98Å; F85-Y427 HydrophobicContact CG-CE2 4.19Å; F85-Y427 HydrophobicContact CZ-CD2 4.02Å; F85-Y427 HydrophobicContact CZ-CE1 4.29Å; F85-Y427 AromaticContact CZ-CE2 3.29Å; F85-Y427 HydrophobicContact CZ-CE2 3.29Å; F85-Y427 AromaticContact CZ-CZ 3.46Å; F85-Y427 VanDerWaalsContact CZ-CZ 3.46Å; F85-Y427 WeakPolarHBondContact CZ-OH 3.34Å; F85-Y427 WeakPolarHBondContact O-CE2 3.31Å; F88-Y427 HydrophobicContact CB-CD2 4.06Å; G89-Y427 VanDerWaalsContact CA-CD2 3.45Å; G89-Y427 VanDerWaalsContact N-CD2 3.29Å; W393-Y427 WeakPolarHBondContact CZ3-OH 3.37Å; V396-Y427 HydrophobicContact CG1-CE1 3.87Å; V396-Y427 WeakPolarHBondContact CG1-OH 3.38Å; V400-Y427 HydrophobicContact CB-CD1 3.93Å; V400-Y427 HydrophobicContact CB-CE1 4.44Å; V400-Y427 HydrophobicContact CG1-CD1 4.03Å; V400-Y427 HydrophobicContact CG2-CD1 3.62Å; V400-Y427 HydrophobicContact CG2-CE1 3.81Å; F423-Y427 WeakPolarHBondContact O-CB 3.47Å; F423-Y427 PolarHBondContact O-N 3.2Å; P424-Y427 PolarHBondContact O-N 2.89Å; F425-Y427 VanDerWaalsContact C-N 3.3Å; F425-Y427 PolarHBondContact O-N 3.37Å; Y427-L429 VanDerWaalsContact C-N 3.34Å; Y427-L429 PolarHBondContact O-N 3.12Å; Y427-C430 PolarHBondContact O-N 3.47Å; Y427-S431 VanDerWaalsContact CE1-OG 3.29Å; Y427-S431 WeakPolarHBondContact CE1-OG 3.11Å; Y427-S431 WeakPolarHBondContact O-CB 3.17Å; Y427-S431 PolarHBondContact O-N 2.83Å; Y427-S431 PolarHBondContact O-OG 2.95Å
428	C	94.7	Very high	91.7	Very high	20 Å²	20	55.4 Å²	55.4	14%	0.135	28%	0.283	C	S	.	.	H	α-helix	trans	-61.7	-41.3	174.8	-75	0	0	0	0	111.8	P424 F425 S431 L432	P424-C428 WeakPolarHBondContact O-CB 3.38Å; P424-C428 PolarHBondContact O-N 2.81Å; P424-C428 PolarHBondContact O-SG 3.24Å; F425-C428 PolarHBondContact O-N 2.96Å; C428-S431 PolarHBondContact O-N 3.3Å; C428-L432 WeakPolarHBondContact O-CG 3.21Å; C428-L432 PolarHBondContact O-N 3.49Å
429	L	93.8	Very high	91.5	Very high	122 Å²	122	50.3 Å²	50.3	64%	0.639	26%	0.263	S	S	*	.	H	α-helix	trans	-63.2	-45.8	177	-176.7	64.8	0	0	0	111.7	F425 V426 Y427 S431 L432 F433	F425-L429 PolarHBondContact O-N 3.48Å; V426-L429 PolarHBondContact O-N 3.31Å; Y427-L429 VanDerWaalsContact C-N 3.34Å; Y427-L429 PolarHBondContact O-N 3.12Å; L429-S431 VanDerWaalsContact C-N 3.34Å; L429-L432 WeakPolarHBondContact O-CB 3.47Å; L429-L432 PolarHBondContact O-N 3.45Å; L429-F433 PolarHBondContact O-N 3.17Å
430	C	92.3	Very high	91.2	Very high	49 Å²	49	57.7 Å²	57.7	33%	0.331	29%	0.29	S	S	.	.	H	α-helix	trans	-65.5	-37.4	175.7	-69.8	0	0	0	0	112	F85 V426 Y427 L432 F433 L434	F85-C430 HydrophobicContact CD2-CB 3.56Å; F85-C430 HydrophobicContact CE2-CB 3.42Å; F85-C430 VanDerWaalsContact CE2-CB 3.42Å; V426-C430 PolarHBondContact O-N 3.19Å; V426-C430 PolarHBondContact O-SG 3.28Å; Y427-C430 PolarHBondContact O-N 3.47Å; C430-L432 VanDerWaalsContact C-N 3.35Å; C430-F433 WeakPolarHBondContact O-CB 3.48Å; C430-F433 PolarHBondContact O-N 2.96Å; C430-L434 WeakPolarHBondContact O-CG 3.26Å; C430-L434 PolarHBondContact O-N 2.97Å
431	S	91.9	Very high	90.4	Very high	5 Å²	5	56 Å²	56	4%	0.035	28%	0.284	C	S	.	.	H	α-helix	trans	-64.9	-39.1	175.1	-57.9	0	0	0	0	111.5	Y427 C428 L429 L434 V435	Y427-S431 VanDerWaalsContact CE1-OG 3.29Å; Y427-S431 WeakPolarHBondContact CE1-OG 3.11Å; Y427-S431 WeakPolarHBondContact O-CB 3.17Å; Y427-S431 PolarHBondContact O-N 2.83Å; Y427-S431 PolarHBondContact O-OG 2.95Å; C428-S431 PolarHBondContact O-N 3.3Å; L429-S431 VanDerWaalsContact C-N 3.34Å; S431-L434 PolarHBondContact O-N 2.93Å; S431-V435 WeakPolarHBondContact O-CG2 3.29Å; S431-V435 PolarHBondContact O-N 3.19Å
432	L	91.4	Very high	89.8	Confident	99 Å²	99	54.5 Å²	54.5	52%	0.518	28%	0.277	S	S	.	.	H	α-helix	trans	-62.7	-42.6	172.8	-76.4	169.1	0	0	0	111.7	C428 L429 C430 L434 V435 I436	C428-L432 WeakPolarHBondContact O-CG 3.21Å; C428-L432 PolarHBondContact O-N 3.49Å; L429-L432 WeakPolarHBondContact O-CB 3.47Å; L429-L432 PolarHBondContact O-N 3.45Å; C430-L432 VanDerWaalsContact C-N 3.35Å; L432-L434 VanDerWaalsContact C-N 3.32Å; L432-L434 PolarHBondContact O-N 3.36Å; L432-V435 PolarHBondContact O-N 3.49Å; L432-V435 VanDerWaalsContact O-N 3.16Å; L432-I436 HydrophobicContact CB-CD1 4.32Å; L432-I436 WeakPolarHBondContact O-CB 3.3Å; L432-I436 VanDerWaalsContact O-CG1 3.24Å; L432-I436 WeakPolarHBondContact O-CG1 3.46Å; L432-I436 PolarHBondContact O-N 3.48Å
433	F	90.4	Very high	89.5	Confident	82 Å²	82	51.7 Å²	51.7	36%	0.36	27%	0.27	S	S	.	.	H	α-helix	trans	-57.5	-46.5	173.2	171	-91.2	0	0	0	111.4	A232 L235 L429 C430 V435 I436 V437	A232-F433 HydrophobicContact CB-CE1 4.31Å; L235-F433 HydrophobicContact CD1-CE1 4.18Å; L429-F433 PolarHBondContact O-N 3.17Å; C430-F433 WeakPolarHBondContact O-CB 3.48Å; C430-F433 PolarHBondContact O-N 2.96Å; F433-V435 PolarHBondContact O-N 3.22Å; F433-I436 PolarHBondContact O-N 3.05Å; F433-V437 HydrophobicContact CD2-CG2 3.59Å; F433-V437 HydrophobicContact CE2-CB 4.43Å; F433-V437 HydrophobicContact CE2-CG2 3.47Å; F433-V437 VanDerWaalsContact CE2-CG2 3.47Å; F433-V437 HydrophobicContact CG-CG2 4.23Å; F433-V437 HydrophobicContact CZ-CB 4.5Å; F433-V437 HydrophobicContact CZ-CG2 3.99Å; F433-V437 WeakPolarHBondContact O-CB 3.41Å; F433-V437 WeakPolarHBondContact O-CG2 3.26Å; F433-V437 PolarHBondContact O-N 2.86Å
434	L	87.9	Confident	89.2	Confident	4 Å²	4	55 Å²	55	2%	0.021	29%	0.289	C	S	.	.	H	α-helix	trans	-65.1	-22.3	178.1	-71.9	175.5	0	0	0	113.2	F85 L235 Y236 L239 W393 C430 S431 L432 P438	F85-L434 HydrophobicContact CE1-CD1 3.86Å; F85-L434 HydrophobicContact CE2-CD1 4.11Å; F85-L434 HydrophobicContact CZ-CD1 3.59Å; L235-L434 HydrophobicContact CB-CD2 4.06Å; L235-L434 HydrophobicContact CD1-CD2 4.35Å; Y236-L434 HydrophobicContact CD1-CD2 4.05Å; Y236-L434 HydrophobicContact CE1-CB 4.06Å; Y236-L434 HydrophobicContact CE1-CD2 3.96Å; Y236-L434 VanDerWaalsContact CE1-O 3.27Å; Y236-L434 WeakPolarHBondContact CE1-O 3.31Å; Y236-L434 VanDerWaalsContact CZ-O 3.25Å; Y236-L434 PolarHBondContact OH-O 2.91Å; L239-L434 HydrophobicContact CD1-CD1 3.44Å; L239-L434 VanDerWaalsContact CD1-CD1 3.44Å; L239-L434 HydrophobicContact CD1-CD2 4.09Å; L239-L434 HydrophobicContact CD1-CG 4.43Å; W393-L434 HydrophobicContact CG-CD1 4.34Å; C430-L434 WeakPolarHBondContact O-CG 3.26Å; C430-L434 PolarHBondContact O-N 2.97Å; S431-L434 PolarHBondContact O-N 2.93Å; L432-L434 VanDerWaalsContact C-N 3.32Å; L432-L434 PolarHBondContact O-N 3.36Å; L434-P438 WeakPolarHBondContact O-CD 3.29Å; L434-P438 VanDerWaalsContact O-CG 3.27Å; L434-P438 WeakPolarHBondContact O-CG 3.37Å
435	V	89.1	Confident	88.7	Confident	19 Å²	19	55.7 Å²	55.7	12%	0.115	29%	0.292	C	S	.	.	H	α-helix	trans	-90.7	-41.5	175.2	171.6	0	0	0	0	111.2	F390 L394 S431 L432 F433 L439	F390-V435 HydrophobicContact CE2-CB 4.43Å; F390-V435 HydrophobicContact CE2-CG1 3.76Å; F390-V435 WeakPolarHBondContact CE2-O 3.38Å; F390-V435 HydrophobicContact CZ-CG1 3.96Å; L394-V435 HydrophobicContact CB-CG2 3.9Å; L394-V435 HydrophobicContact CD1-CG1 4.19Å; L394-V435 HydrophobicContact CD1-CG2 3.97Å; S431-V435 WeakPolarHBondContact O-CG2 3.29Å; S431-V435 PolarHBondContact O-N 3.19Å; L432-V435 PolarHBondContact O-N 3.49Å; L432-V435 VanDerWaalsContact O-N 3.16Å; F433-V435 PolarHBondContact O-N 3.22Å; V435-L439 WeakPolarHBondContact O-CG 3.4Å
436	I	89.6	Confident	88.3	Confident	80 Å²	80	50.9 Å²	50.9	41%	0.41	27%	0.272	S	S	.	.	H	α-helix	trans	-76.1	-44.8	-171.8	-67.5	167.7	0	0	0	111.7	L432 F433 L439 Y440	L432-I436 HydrophobicContact CB-CD1 4.32Å; L432-I436 WeakPolarHBondContact O-CB 3.3Å; L432-I436 VanDerWaalsContact O-CG1 3.24Å; L432-I436 WeakPolarHBondContact O-CG1 3.46Å; L432-I436 PolarHBondContact O-N 3.48Å; F433-I436 PolarHBondContact O-N 3.05Å; I436-L439 WeakPolarHBondContact O-CB 3.35Å; I436-L439 PolarHBondContact O-N 3.37Å; I436-Y440 HydrophobicContact CG2-CE2 4.06Å; I436-Y440 WeakPolarHBondContact O-CD2 3.48Å
437	V	87.1	Confident	88	Confident	25 Å²	25	53.6 Å²	53.6	15%	0.152	28%	0.284	C	S	.	.	H	α-helix	trans	-66	-41.6	-173.9	174.9	0	0	0	0	112.3	P228 A232 F433 L439 Y440 G441	P228-V437 HydrophobicContact CB-CG1 4.26Å; P228-V437 WeakPolarHBondContact O-CG1 3.16Å; A232-V437 HydrophobicContact CB-CB 4.02Å; A232-V437 HydrophobicContact CB-CG1 3.59Å; F433-V437 HydrophobicContact CD2-CG2 3.59Å; F433-V437 HydrophobicContact CE2-CB 4.43Å; F433-V437 HydrophobicContact CE2-CG2 3.47Å; F433-V437 VanDerWaalsContact CE2-CG2 3.47Å; F433-V437 HydrophobicContact CG-CG2 4.23Å; F433-V437 HydrophobicContact CZ-CB 4.5Å; F433-V437 HydrophobicContact CZ-CG2 3.99Å; F433-V437 WeakPolarHBondContact O-CB 3.41Å; F433-V437 WeakPolarHBondContact O-CG2 3.26Å; F433-V437 PolarHBondContact O-N 2.86Å; V437-L439 PolarHBondContact O-N 3.03Å; V437-Y440 PolarHBondContact O-N 2.93Å; V437-G441 PolarHBondContact O-N 2.83Å; V437-G441 VanDerWaalsContact O-N 3.08Å
438	P	83.2	Confident	87.8	Confident	1 Å²	1	56.7 Å²	56.7	1%	0.006	30%	0.3	C	S	.	.	H	α-helix	trans	-67	-18.3	176.4	-29.5	44.1	0	0	0	114.5	A232 Y236 L434 Y440 G441 D442 S446	A232-P438 HydrophobicContact CB-CG 4.03Å; Y236-P438 HydrophobicContact CE1-CG 3.95Å; Y236-P438 HydrophobicContact CE2-CB 4.07Å; Y236-P438 HydrophobicContact CE2-CG 3.93Å; Y236-P438 WeakPolarHBondContact OH-CG 3.39Å; L434-P438 WeakPolarHBondContact O-CD 3.29Å; L434-P438 VanDerWaalsContact O-CG 3.27Å; L434-P438 WeakPolarHBondContact O-CG 3.37Å; P438-Y440 PolarHBondContact O-N 2.64Å; P438-G441 PolarHBondContact O-N 2.99Å; P438-D442 CarbonylContact O-C 3.46Å; P438-D442 WeakPolarHBondContact O-CA 3.28Å; P438-D442 PolarHBondContact O-N 2.72Å; P438-S446 PolarHBondContact O-OG 2.87Å
439	L	85.6	Confident	87.4	Confident	52 Å²	52	55.8 Å²	55.8	27%	0.272	29%	0.294	S	S	.	.	H	α-helix	trans	-61.5	-26.5	169.9	-68.3	168	0	0	0	112.4	F390 V435 I436 V437 T443 I450	F390-L439 HydrophobicContact CE2-CD2 4.2Å; F390-L439 HydrophobicContact CE2-CG 4.37Å; F390-L439 HydrophobicContact CZ-CD2 4.36Å; V435-L439 WeakPolarHBondContact O-CG 3.4Å; I436-L439 WeakPolarHBondContact O-CB 3.35Å; I436-L439 PolarHBondContact O-N 3.37Å; V437-L439 PolarHBondContact O-N 3.03Å; L439-T443 WeakPolarHBondContact O-CA 3.31Å; L439-T443 VanDerWaalsContact O-CB 3.28Å; L439-T443 WeakPolarHBondContact O-CB 3.31Å; L439-T443 WeakPolarHBondContact O-CG2 3.41Å; L439-T443 PolarHBondContact O-OG1 3.1Å; L439-I450 HydrophobicContact CD2-CD1 3.71Å
440	Y	83.5	Confident	87.2	Confident	190 Å²	190	52.6 Å²	52.6	75%	0.745	28%	0.277	S	S	*	.	H	α-helix	trans	-95.8	-37.8	174.7	-56.3	-80.1	0	0	0	112.3	I436 V437 P438	I436-Y440 HydrophobicContact CG2-CE2 4.06Å; I436-Y440 WeakPolarHBondContact O-CD2 3.48Å; V437-Y440 PolarHBondContact O-N 2.93Å; P438-Y440 PolarHBondContact O-N 2.64Å
441	G	76.7	Confident	87.3	Confident	39 Å²	39	52.1 Å²	52.1	40%	0.402	28%	0.28	S	S	.	.	H	α-helix	trans	-77.2	-33.9	-177.6	0	0	0	0	0	114.8	V437 P438	V437-G441 PolarHBondContact O-N 2.83Å; V437-G441 VanDerWaalsContact O-N 3.08Å; P438-G441 PolarHBondContact O-N 2.99Å
442	D	81.7	Confident	87.3	Confident	28 Å²	28	53.8 Å²	53.8	15%	0.15	29%	0.288	C	S	.	.	S	Bend	trans	-144.3	64.6	-179.5	-169.9	2.8	0	0	0	110	L233 N386 P438 I444 N445 S446	L233-D442 HydrophobicContact CD2-CB 4.18Å; N386-D442 PolarHBondContact ND2-OD2 3.42Å; P438-D442 CarbonylContact O-C 3.46Å; P438-D442 WeakPolarHBondContact O-CA 3.28Å; P438-D442 PolarHBondContact O-N 2.72Å; D442-I444 PolarHBondContact O-N 3.01Å; D442-N445 PolarHBondContact O-N 3.43Å; D442-N445 WeakPolarHBondContact OD1-CB 3.04Å; D442-N445 PolarHBondContact OD1-ND2 3.04Å; D442-N445 WeakPolarHBondContact OD2-CB 3.28Å; D442-N445 PolarHBondContact OD2-ND2 3.48Å; D442-S446 WeakPolarHBondContact O-CB 3.43Å; D442-S446 PolarHBondContact O-N 3.15Å; D442-S446 VanDerWaalsContact O-N 3.12Å; D442-S446 PolarHBondContact O-OG 3.4Å
443	T	86.6	Confident	87.3	Confident	64 Å²	64	49.7 Å²	49.7	39%	0.393	27%	0.269	S	S	.	.	H	α-helix	trans	-59.9	-44.1	-170	-50.1	0	0	0	0	112.6	L439 S446 L447	L439-T443 WeakPolarHBondContact O-CA 3.31Å; L439-T443 VanDerWaalsContact O-CB 3.28Å; L439-T443 WeakPolarHBondContact O-CB 3.31Å; L439-T443 WeakPolarHBondContact O-CG2 3.41Å; L439-T443 PolarHBondContact O-OG1 3.1Å; T443-S446 PolarHBondContact O-N 2.77Å; T443-L447 HydrophobicContact CG2-CD1 3.79Å; T443-L447 HydrophobicContact CG2-CG 4.18Å; T443-L447 VanDerWaalsContact O-CB 3.32Å; T443-L447 WeakPolarHBondContact O-CB 3.5Å; T443-L447 WeakPolarHBondContact O-CG 3.47Å; T443-L447 PolarHBondContact O-N 3.21Å
444	I	88.1	Confident	87.5	Confident	125 Å²	125	50.9 Å²	50.9	64%	0.641	28%	0.279	S	S	*	.	H	α-helix	trans	-63.7	-48.4	-175.5	-63.6	175.8	0	0	0	109.8	D442 S446 L447 I448	D442-I444 PolarHBondContact O-N 3.01Å; I444-S446 VanDerWaalsContact C-N 3.33Å; I444-S446 PolarHBondContact O-N 2.81Å; I444-L447 PolarHBondContact O-N 3.26Å; I444-I448 HydrophobicContact CG2-CD1 3.99Å; I444-I448 WeakPolarHBondContact O-CG1 3.44Å; I444-I448 PolarHBondContact O-N 3.13Å
445	N	85.4	Confident	87.8	Confident	18 Å²	18	53.1 Å²	53.1	10%	0.096	29%	0.294	C	S	.	.	H	α-helix	trans	-68.1	-37.7	-176.3	-65.9	-31	0	0	0	111.9	Q383 Y387 D442 I448 G449	Q383-N445 PolarHBondContact NE2-OD1 3.07Å; Y387-N445 HydrophobicContact CD1-CB 3.92Å; Y387-N445 HydrophobicContact CE1-CB 3.58Å; Y387-N445 WeakPolarHBondContact CE1-OD1 3.45Å; Y387-N445 PolarHBondContact OH-OD1 3.27Å; D442-N445 PolarHBondContact O-N 3.43Å; D442-N445 WeakPolarHBondContact OD1-CB 3.04Å; D442-N445 PolarHBondContact OD1-ND2 3.04Å; D442-N445 WeakPolarHBondContact OD2-CB 3.28Å; D442-N445 PolarHBondContact OD2-ND2 3.48Å; N445-I448 PolarHBondContact O-N 3.05Å; N445-G449 PolarHBondContact O-N 3.42Å
446	S	86.1	Confident	88	Confident	4 Å²	4	52.2 Å²	52.2	3%	0.028	29%	0.289	C	S	.	.	H	α-helix	trans	-64.9	-41.5	174.9	-55.9	0	0	0	0	112	P438 D442 T443 I444 I448 G449 I450	P438-S446 PolarHBondContact O-OG 2.87Å; D442-S446 WeakPolarHBondContact O-CB 3.43Å; D442-S446 PolarHBondContact O-N 3.15Å; D442-S446 VanDerWaalsContact O-N 3.12Å; D442-S446 PolarHBondContact O-OG 3.4Å; T443-S446 PolarHBondContact O-N 2.77Å; I444-S446 VanDerWaalsContact C-N 3.33Å; I444-S446 PolarHBondContact O-N 2.81Å; S446-I448 PolarHBondContact O-N 2.85Å; S446-G449 PolarHBondContact O-N 2.91Å; S446-I450 WeakPolarHBondContact O-CG1 3.16Å; S446-I450 PolarHBondContact O-N 3.46Å
447	L	89.7	Confident	88.2	Confident	98 Å²	98	50.3 Å²	50.3	51%	0.513	28%	0.281	S	S	.	.	H	α-helix	trans	-65.8	-35.5	176.7	-75.5	176.6	0	0	0	112.6	T443 I444 G449 I450 G451	T443-L447 HydrophobicContact CG2-CD1 3.79Å; T443-L447 HydrophobicContact CG2-CG 4.18Å; T443-L447 VanDerWaalsContact O-CB 3.32Å; T443-L447 WeakPolarHBondContact O-CB 3.5Å; T443-L447 WeakPolarHBondContact O-CG 3.47Å; T443-L447 PolarHBondContact O-N 3.21Å; I444-L447 PolarHBondContact O-N 3.26Å; L447-G449 VanDerWaalsContact C-N 3.35Å; L447-I450 PolarHBondContact O-N 3.33Å; L447-G451 PolarHBondContact O-N 3.18Å
448	I	88.1	Confident	88.5	Confident	66 Å²	66	52.9 Å²	52.9	34%	0.338	30%	0.298	S	S	.	.	H	α-helix	trans	-61.6	-45.7	173.1	-69.3	165.8	0	0	0	110.1	Y387 I444 N445 S446 I450 G451 I452	Y387-I448 HydrophobicContact CE1-CB 4.15Å; Y387-I448 HydrophobicContact CE1-CD1 4.06Å; Y387-I448 HydrophobicContact CE1-CG2 4.12Å; Y387-I448 WeakPolarHBondContact OH-CD1 3.33Å; I444-I448 HydrophobicContact CG2-CD1 3.99Å; I444-I448 WeakPolarHBondContact O-CG1 3.44Å; I444-I448 PolarHBondContact O-N 3.13Å; N445-I448 PolarHBondContact O-N 3.05Å; S446-I448 PolarHBondContact O-N 2.85Å; I448-I450 PolarHBondContact O-N 3.17Å; I448-G451 PolarHBondContact O-N 3.1Å; I448-I452 HydrophobicContact CG2-CD1 3.88Å; I448-I452 WeakPolarHBondContact O-CG1 3.39Å; I448-I452 PolarHBondContact O-N 3.24Å
449	G	86.9	Confident	88.9	Confident	1 Å²	1	55.3 Å²	55.3	1%	0.01	31%	0.313	C	S	.	.	H	α-helix	trans	-58.7	-45.4	175.7	0	0	0	0	0	112.9	N445 S446 L447 I452 A453	N445-G449 PolarHBondContact O-N 3.42Å; S446-G449 PolarHBondContact O-N 2.91Å; L447-G449 VanDerWaalsContact C-N 3.35Å; G449-I452 PolarHBondContact O-N 3.12Å; G449-A453 PolarHBondContact O-N 3.37Å
450	I	90.9	Very high	89.1	Confident	56 Å²	56	54.1 Å²	54.1	29%	0.287	31%	0.305	S	S	.	.	H	α-helix	trans	-63.1	-44.3	174.6	-66.7	169.2	0	0	0	111	F390 L439 S446 L447 I448 I452 A453 L454	F390-I450 HydrophobicContact CE1-CD1 4.44Å; F390-I450 HydrophobicContact CE1-CG1 3.8Å; F390-I450 HydrophobicContact CZ-CD1 3.97Å; F390-I450 HydrophobicContact CZ-CG1 3.82Å; L439-I450 HydrophobicContact CD2-CD1 3.71Å; S446-I450 WeakPolarHBondContact O-CG1 3.16Å; S446-I450 PolarHBondContact O-N 3.46Å; L447-I450 PolarHBondContact O-N 3.33Å; I448-I450 PolarHBondContact O-N 3.17Å; I450-I452 VanDerWaalsContact C-N 3.33Å; I450-I452 PolarHBondContact O-N 3.05Å; I450-A453 PolarHBondContact O-N 2.97Å; I450-L454 HydrophobicContact CG2-CD1 3.73Å; I450-L454 HydrophobicContact CG2-CG 4.1Å; I450-L454 WeakPolarHBondContact O-CB 3.21Å; I450-L454 WeakPolarHBondContact O-CG 3.31Å; I450-L454 PolarHBondContact O-N 3.35Å
451	G	93.1	Very high	89.3	Confident	38 Å²	38	50.4 Å²	50.4	39%	0.392	29%	0.291	S	S	.	.	H	α-helix	trans	-59.7	-42.5	179.1	0	0	0	0	0	112.3	L447 I448 L454 S455	L447-G451 PolarHBondContact O-N 3.18Å; I448-G451 PolarHBondContact O-N 3.1Å; G451-L454 PolarHBondContact O-N 3.31Å; G451-S455 WeakPolarHBondContact O-CB 3.39Å; G451-S455 PolarHBondContact O-N 3.4Å
452	I	91.7	Very high	89.8	Confident	40 Å²	40	51 Å²	51	21%	0.205	29%	0.286	C	S	.	.	H	α-helix	trans	-65.8	-43.3	175.5	-70.2	165.5	0	0	0	110.8	W124 L128 L129 I448 G449 I450 L454 S455	W124-I452 PolarHBondContact NE1-O 3.22Å; L128-I452 HydrophobicContact CB-CG2 3.99Å; L128-I452 HydrophobicContact CD1-CG2 4.34Å; L129-I452 HydrophobicContact CB-CD1 4.46Å; L129-I452 HydrophobicContact CB-CG2 4.36Å; L129-I452 HydrophobicContact CD1-CD1 3.5Å; I448-I452 HydrophobicContact CG2-CD1 3.88Å; I448-I452 WeakPolarHBondContact O-CG1 3.39Å; I448-I452 PolarHBondContact O-N 3.24Å; G449-I452 PolarHBondContact O-N 3.12Å; I450-I452 VanDerWaalsContact C-N 3.33Å; I450-I452 PolarHBondContact O-N 3.05Å; I452-L454 PolarHBondContact O-N 3.13Å; I452-S455 WeakPolarHBondContact O-CB 3.49Å; I452-S455 PolarHBondContact O-N 2.99Å; I452-S455 PolarHBondContact O-OG 3.24Å
453	A	92.3	Very high	89.9	Confident	14 Å²	14	51.4 Å²	51.4	12%	0.116	29%	0.293	C	S	.	.	H	α-helix	trans	-60.7	-46.2	174.9	0	0	0	0	0	111.7	I121 G449 I450 S455 G456	I121-A453 HydrophobicContact CG2-CB 4.22Å; G449-A453 PolarHBondContact O-N 3.37Å; I450-A453 PolarHBondContact O-N 2.97Å; A453-S455 VanDerWaalsContact C-N 3.31Å; A453-S455 PolarHBondContact O-N 3.39Å; A453-G456 PolarHBondContact O-N 2.92Å; A453-G456 VanDerWaalsContact O-N 3.13Å
454	L	93.9	Very high	89.8	Confident	107 Å²	107	49.9 Å²	49.9	56%	0.56	28%	0.282	S	S	*	.	H	α-helix	trans	-66.8	-29.1	178.5	-70	178.6	0	0	0	113	I450 G451 I452 G456 V457 P458	I450-L454 HydrophobicContact CG2-CD1 3.73Å; I450-L454 HydrophobicContact CG2-CG 4.1Å; I450-L454 WeakPolarHBondContact O-CB 3.21Å; I450-L454 WeakPolarHBondContact O-CG 3.31Å; I450-L454 PolarHBondContact O-N 3.35Å; G451-L454 PolarHBondContact O-N 3.31Å; I452-L454 PolarHBondContact O-N 3.13Å; L454-G456 PolarHBondContact O-N 2.88Å; L454-V457 HydrophobicContact CD2-CG2 4.4Å; L454-V457 WeakPolarHBondContact O-CB 3.41Å; L454-V457 WeakPolarHBondContact O-CG2 3.35Å; L454-V457 PolarHBondContact O-N 3.46Å; L454-P458 VanDerWaalsContact O-CD 3.31Å; L454-P458 WeakPolarHBondContact O-CD 3.46Å
455	S	95.2	Very high	89.6	Confident	50 Å²	50	51.5 Å²	51.5	35%	0.35	28%	0.282	S	S	.	.	H	α-helix	trans	-61.6	-22.7	173.7	78.7	0	0	0	0	112.8	W124 G451 I452 A453 V457 P458	W124-S455 PolarHBondContact NE1-OG 3Å; G451-S455 WeakPolarHBondContact O-CB 3.39Å; G451-S455 PolarHBondContact O-N 3.4Å; I452-S455 WeakPolarHBondContact O-CB 3.49Å; I452-S455 PolarHBondContact O-N 2.99Å; I452-S455 PolarHBondContact O-OG 3.24Å; A453-S455 VanDerWaalsContact C-N 3.31Å; A453-S455 PolarHBondContact O-N 3.39Å; S455-V457 VanDerWaalsContact C-N 3.33Å; S455-P458 VanDerWaalsContact O-CD 3.31Å; S455-P458 WeakPolarHBondContact O-CD 3.28Å; S455-P458 WeakPolarHBondContact O-CG 3.12Å
456	G	92.8	Very high	89.5	Confident	0 Å²	0	53.1 Å²	53.1	0%	0	29%	0.29	C	S	.	.	H	α-helix	trans	-70.7	-27.1	173.8	0	0	0	0	0	113.1	F120 W124 A453 L454 V459 Y460	F120-G456 VanDerWaalsContact CE1-O 3.26Å; F120-G456 WeakPolarHBondContact CE1-O 3.39Å; W124-G456 VanDerWaalsContact CD1-CA 3.46Å; A453-G456 PolarHBondContact O-N 2.92Å; A453-G456 VanDerWaalsContact O-N 3.13Å; L454-G456 PolarHBondContact O-N 2.88Å; G456-V459 PolarHBondContact O-N 3.16Å; G456-Y460 WeakPolarHBondContact O-CB 3.47Å; G456-Y460 PolarHBondContact O-N 3.38Å
457	V	93.9	Very high	89	Confident	41 Å²	41	56.1 Å²	56.1	25%	0.248	31%	0.31	C	S	.	.	H	α-helix	trans	-58.1	-54.7	-177.6	-178.7	0	0	0	0	112.6	F117 I121 L454 S455 V459 Y460 Y461	F117-V457 HydrophobicContact CE2-CG1 4.33Å; F117-V457 HydrophobicContact CE2-CG2 4.34Å; F117-V457 HydrophobicContact CZ-CG1 4.38Å; F117-V457 HydrophobicContact CZ-CG2 4.01Å; I121-V457 HydrophobicContact CD1-CG2 3.89Å; L454-V457 HydrophobicContact CD2-CG2 4.4Å; L454-V457 WeakPolarHBondContact O-CB 3.41Å; L454-V457 WeakPolarHBondContact O-CG2 3.35Å; L454-V457 PolarHBondContact O-N 3.46Å; S455-V457 VanDerWaalsContact C-N 3.33Å; V457-V459 VanDerWaalsContact C-N 3.26Å; V457-V459 PolarHBondContact O-N 2.96Å; V457-Y460 PolarHBondContact O-N 3.48Å; V457-Y461 HydrophobicContact CG1-CD2 3.9Å; V457-Y461 HydrophobicContact CG1-CE2 3.77Å; V457-Y461 VanDerWaalsContact O-CD2 3.27Å; V457-Y461 WeakPolarHBondContact O-CD2 3.21Å; V457-Y461 PolarHBondContact O-N 3.03Å
458	P	92.9	Very high	88.2	Confident	79 Å²	79	58.4 Å²	58.4	51%	0.513	32%	0.318	S	S	.	.	H	α-helix	trans	-62.2	-35.3	177.7	24.4	-34.4	0	0	0	112.2	L454 S455 Y461 V462	L454-P458 VanDerWaalsContact O-CD 3.31Å; L454-P458 WeakPolarHBondContact O-CD 3.46Å; S455-P458 VanDerWaalsContact O-CD 3.31Å; S455-P458 WeakPolarHBondContact O-CD 3.28Å; S455-P458 WeakPolarHBondContact O-CG 3.12Å; P458-Y461 PolarHBondContact O-N 3.23Å; P458-V462 WeakPolarHBondContact O-CB 3.36Å; P458-V462 VanDerWaalsContact O-CG2 3.26Å; P458-V462 WeakPolarHBondContact O-CG2 3.45Å; P458-V462 PolarHBondContact O-N 2.9Å; P458-V462 VanDerWaalsContact O-N 3.07Å
459	V	91.1	Very high	87.5	Confident	52 Å²	52	63 Å²	63	32%	0.315	34%	0.343	S	S	.	.	H	α-helix	trans	-65.4	-44.2	178.3	-179.5	0	0	0	0	110.9	F120 W124 G456 V457 Y461 V462 A463	F120-V459 HydrophobicContact CZ-CB 4.3Å; F120-V459 HydrophobicContact CZ-CG1 3.98Å; W124-V459 HydrophobicContact CH2-CB 4.34Å; W124-V459 HydrophobicContact CH2-CG1 4.01Å; W124-V459 HydrophobicContact CH2-CG2 3.93Å; W124-V459 HydrophobicContact CZ2-CG2 3.96Å; W124-V459 HydrophobicContact CZ3-CG1 3.94Å; G456-V459 PolarHBondContact O-N 3.16Å; V457-V459 VanDerWaalsContact C-N 3.26Å; V457-V459 PolarHBondContact O-N 2.96Å; V459-Y461 PolarHBondContact O-N 3.3Å; V459-V462 PolarHBondContact O-N 3.15Å; V459-A463 HydrophobicContact CG1-CB 4.46Å; V459-A463 WeakPolarHBondContact O-CB 3.45Å; V459-A463 PolarHBondContact O-N 3.05Å
460	Y	90.4	Very high	87.1	Confident	27 Å²	27	72 Å²	72	11%	0.106	38%	0.377	C	S	.	.	H	α-helix	trans	-58.4	-49.3	177.2	-179.2	-96.8	0	0	0	111.8	F117 F120 G456 V457 V462 I464 Y465	F117-Y460 HydrophobicContact CB-CE1 4.05Å; F117-Y460 AromaticContact CD2-CD1 3.49Å; F117-Y460 HydrophobicContact CD2-CD1 3.49Å; F117-Y460 VanDerWaalsContact CD2-CD1 3.49Å; F117-Y460 HydrophobicContact CD2-CD2 4.43Å; F117-Y460 AromaticContact CD2-CE1 3.69Å; F117-Y460 HydrophobicContact CD2-CE1 3.69Å; F117-Y460 AromaticContact CD2-CG 3.87Å; F117-Y460 HydrophobicContact CD2-CG 3.87Å; F117-Y460 HydrophobicContact CE2-CD1 4.12Å; F117-Y460 HydrophobicContact CE2-CG 4.41Å; F117-Y460 HydrophobicContact CG-CE1 4.35Å; F117-Y460 PolarHBondContact N-OH 3.14Å; F120-Y460 HydrophobicContact CB-CD2 3.52Å; F120-Y460 HydrophobicContact CB-CE2 3.85Å; F120-Y460 AromaticContact CD1-CD2 3.66Å; F120-Y460 HydrophobicContact CD1-CD2 3.66Å; F120-Y460 HydrophobicContact CD1-CG 4.08Å; F120-Y460 HydrophobicContact CD2-CD2 4.19Å; F120-Y460 HydrophobicContact CE1-CD2 4.45Å; F120-Y460 AromaticContact CG-CD2 3.5Å; F120-Y460 HydrophobicContact CG-CD2 3.5Å; F120-Y460 HydrophobicContact CG-CE2 4.29Å; F120-Y460 HydrophobicContact CG-CG 4.37Å; G456-Y460 WeakPolarHBondContact O-CB 3.47Å; G456-Y460 PolarHBondContact O-N 3.38Å; V457-Y460 PolarHBondContact O-N 3.48Å; Y460-V462 PolarHBondContact O-N 3.35Å; Y460-I464 HydrophobicContact CD2-CB 4.07Å; Y460-I464 HydrophobicContact CD2-CD1 3.69Å; Y460-I464 HydrophobicContact CD2-CG1 4.48Å; Y460-I464 HydrophobicContact CD2-CG2 4.27Å; Y460-I464 HydrophobicContact CE2-CB 4.14Å; Y460-I464 HydrophobicContact CE2-CD1 4.16Å; Y460-I464 HydrophobicContact CE2-CG2 3.83Å; Y460-I464 WeakPolarHBondContact O-CA 3.27Å; Y460-I464 WeakPolarHBondContact O-CB 3.46Å; Y460-I464 PolarHBondContact O-N 3.35Å; Y460-Y465 HydrophobicContact CE1-CD2 4.41Å; Y460-Y465 PolarHBondContact O-N 3.01Å
461	Y	89.1	Confident	86.7	Confident	112 Å²	112	72.5 Å²	72.5	44%	0.439	38%	0.375	S	S	.	.	I	π-helix	trans	-64.9	-42	-177.7	-79.7	-70.9	0	0	0	111.8	F117 V457 P458 V459 Y465 L466	F117-Y461 HydrophobicContact CE2-CE2 4.25Å; V457-Y461 HydrophobicContact CG1-CD2 3.9Å; V457-Y461 HydrophobicContact CG1-CE2 3.77Å; V457-Y461 VanDerWaalsContact O-CD2 3.27Å; V457-Y461 WeakPolarHBondContact O-CD2 3.21Å; V457-Y461 PolarHBondContact O-N 3.03Å; P458-Y461 PolarHBondContact O-N 3.23Å; V459-Y461 PolarHBondContact O-N 3.3Å; Y461-Y465 AromaticContact CD1-CD1 3.77Å; Y461-Y465 HydrophobicContact CD1-CD1 3.77Å; Y461-Y465 HydrophobicContact CD1-CE1 4.44Å; Y461-Y465 AromaticContact CD1-CG 3.88Å; Y461-Y465 HydrophobicContact CD1-CG 3.88Å; Y461-Y465 HydrophobicContact CE1-CD1 4.19Å; Y461-Y465 HydrophobicContact CE1-CG 4.21Å; Y461-L466 VanDerWaalsContact O-CD1 3.3Å; Y461-L466 WeakPolarHBondContact O-CD1 3.41Å; Y461-L466 PolarHBondContact O-N 3.12Å; Y461-L466 VanDerWaalsContact O-N 3.16Å
462	V	86.6	Confident	86.3	Confident	51 Å²	51	73.5 Å²	73.5	31%	0.309	37%	0.374	S	S	.	.	I	π-helix	trans	-74.7	-41.5	-177.8	174.6	0	0	0	0	113.1	P458 V459 Y460 P472 I475	P458-V462 WeakPolarHBondContact O-CB 3.36Å; P458-V462 VanDerWaalsContact O-CG2 3.26Å; P458-V462 WeakPolarHBondContact O-CG2 3.45Å; P458-V462 PolarHBondContact O-N 2.9Å; P458-V462 VanDerWaalsContact O-N 3.07Å; V459-V462 PolarHBondContact O-N 3.15Å; Y460-V462 PolarHBondContact O-N 3.35Å; V462-P472 HydrophobicContact CG1-CG 3.89Å; V462-I475 HydrophobicContact CG1-CD1 3.51Å
463	A	83.2	Confident	85.9	Confident	36 Å²	36	79 Å²	79	30%	0.298	40%	0.397	S	S	.	.	I	π-helix	trans	-96.4	-28.3	-170	0	0	0	0	0	114	V459 R471	V459-A463 HydrophobicContact CG1-CB 4.46Å; V459-A463 WeakPolarHBondContact O-CB 3.45Å; V459-A463 PolarHBondContact O-N 3.05Å; A463-R471 PolarHBondContact O-NE 3.24Å; A463-R471 PolarHBondContact O-NH2 2.87Å
464	I	84	Confident	85.5	Confident	32 Å²	32	85.5 Å²	85.5	16%	0.164	42%	0.422	C	S	.	.	I	π-helix	trans	-116.4	-57.4	-170.9	-61	163.3	0	0	0	110.8	F120 H346 Y460 L466 R471	F120-I464 HydrophobicContact CD2-CD1 3.2Å; F120-I464 HydrophobicContact CE2-CD1 3.39Å; F120-I464 HydrophobicContact CG-CD1 3.91Å; F120-I464 HydrophobicContact CZ-CD1 4.24Å; H346-I464 HydrophobicContact CB-CD1 4.27Å; Y460-I464 HydrophobicContact CD2-CB 4.07Å; Y460-I464 HydrophobicContact CD2-CD1 3.69Å; Y460-I464 HydrophobicContact CD2-CG1 4.48Å; Y460-I464 HydrophobicContact CD2-CG2 4.27Å; Y460-I464 HydrophobicContact CE2-CB 4.14Å; Y460-I464 HydrophobicContact CE2-CD1 4.16Å; Y460-I464 HydrophobicContact CE2-CG2 3.83Å; Y460-I464 WeakPolarHBondContact O-CA 3.27Å; Y460-I464 WeakPolarHBondContact O-CB 3.46Å; Y460-I464 PolarHBondContact O-N 3.35Å; I464-L466 PolarHBondContact O-N 3.31Å; I464-R471 PolarHBondContact O-NH2 2.95Å
465	Y	85.4	Confident	84.9	Confident	159 Å²	159	83.7 Å²	83.7	62%	0.624	41%	0.413	S	S	*	.	I	π-helix	trans	-65.6	-38.1	-174.2	-175.4	-99.1	0	0	0	113.4	Y460 Y461	Y460-Y465 HydrophobicContact CE1-CD2 4.41Å; Y460-Y465 PolarHBondContact O-N 3.01Å; Y461-Y465 AromaticContact CD1-CD1 3.77Å; Y461-Y465 HydrophobicContact CD1-CD1 3.77Å; Y461-Y465 HydrophobicContact CD1-CE1 4.44Å; Y461-Y465 AromaticContact CD1-CG 3.88Å; Y461-Y465 HydrophobicContact CD1-CG 3.88Å; Y461-Y465 HydrophobicContact CE1-CD1 4.19Å; Y461-Y465 HydrophobicContact CE1-CG 4.21Å
466	L	82.4	Confident	84.3	Confident	52 Å²	52	83.9 Å²	83.9	27%	0.272	41%	0.413	S	S	.	.	S	Bend	trans	-66.4	127.7	176.5	-93.1	148.8	0	0	0	110.3	Y461 I464 R470 R471	Y461-L466 VanDerWaalsContact O-CD1 3.3Å; Y461-L466 WeakPolarHBondContact O-CD1 3.41Å; Y461-L466 PolarHBondContact O-N 3.12Å; Y461-L466 VanDerWaalsContact O-N 3.16Å; I464-L466 PolarHBondContact O-N 3.31Å; L466-R470 HydrophobicContact CD2-CB 3.48Å; L466-R470 VanDerWaalsContact CD2-CB 3.48Å; L466-R471 HydrophobicContact CB-CG 4.19Å; L466-R471 PolarHBondContact O-NE 3.34Å
467	P	76.2	Confident	83.9	Confident	68 Å²	68	92.2 Å²	92.2	44%	0.442	45%	0.445	S	S	.	.			trans	-59.6	149.3	174.4	23.1	-31.6	0	0	0	110.1	D469 R470 R471	P467-D469 PolarHBondContact O-N 3.06Å; P467-R470 HydrophobicContact CG-CB 4.29Å; P467-R470 HydrophobicContact CG-CG 4.19Å; P467-R470 PolarHBondContact O-N 3.07Å; P467-R471 PolarHBondContact O-N 3.12Å
468	E	72.8	Confident	83.5	Confident	146 Å²	146	94.2 Å²	94.2	68%	0.682	45%	0.454	S	S	*	.	G	3₁₀ helix	trans	-51.3	-36.4	-170.6	-64.9	-160.9	147.5	0	0	113.4	R470 R471	E468-R470 VanDerWaalsContact C-N 3.27Å; E468-R470 PolarHBondContact O-N 3.44Å; E468-R471 PolarHBondContact O-N 3.39Å; E468-R471 IonicContact OE1-NH1 3.72Å
469	D	72.4	Confident	83.2	Confident	161 Å²	161	93.1 Å²	93.1	86%	0.861	44%	0.443	S	S	*	.	G	3₁₀ helix	trans	-64.4	-27.5	179.3	-55.4	-43.1	0	0	0	114.1	P467	P467-D469 PolarHBondContact O-N 3.06Å
470	R	78.8	Confident	82.9	Confident	192 Å²	192	93.5 Å²	93.5	73%	0.725	45%	0.452	S	S	*	.	G	3₁₀ helix	trans	-101.1	-4.4	-178.8	-63.8	-172	-178.8	-175.6	1.4	113.1	L466 P467 E468	L466-R470 HydrophobicContact CD2-CB 3.48Å; L466-R470 VanDerWaalsContact CD2-CB 3.48Å; P467-R470 HydrophobicContact CG-CB 4.29Å; P467-R470 HydrophobicContact CG-CG 4.19Å; P467-R470 PolarHBondContact O-N 3.07Å; E468-R470 VanDerWaalsContact C-N 3.27Å; E468-R470 PolarHBondContact O-N 3.44Å
471	R	82.8	Confident	82.8	Confident	66 Å²	66	98.8 Å²	98.8	25%	0.249	47%	0.472	C	S	.	.	S	Bend	trans	-66.2	141.5	176.9	-67.6	-179.1	-172.9	174.5	-6.2	110.1	A463 I464 L466 P467 E468 K473	A463-R471 PolarHBondContact O-NE 3.24Å; A463-R471 PolarHBondContact O-NH2 2.87Å; I464-R471 PolarHBondContact O-NH2 2.95Å; L466-R471 HydrophobicContact CB-CG 4.19Å; L466-R471 PolarHBondContact O-NE 3.34Å; P467-R471 PolarHBondContact O-N 3.12Å; E468-R471 PolarHBondContact O-N 3.39Å; E468-R471 IonicContact OE1-NH1 3.72Å; R471-K473 PolarHBondContact O-N 3.08Å; R471-K473 VanDerWaalsContact O-N 3.07Å
472	P	83.8	Confident	82.7	Confident	58 Å²	58	95.9 Å²	95.9	38%	0.377	47%	0.466	S	S	.	.			trans	-56.1	119.4	177.6	-25.6	34.3	0	0	0	111	V462 F474 I475 C476	V462-P472 HydrophobicContact CG1-CG 3.89Å; P472-F474 PolarHBondContact O-N 2.9Å; P472-I475 HydrophobicContact CB-CD1 4.04Å; P472-I475 HydrophobicContact CB-CG1 4.16Å; P472-I475 HydrophobicContact CG-CD1 3.92Å; P472-I475 PolarHBondContact O-N 3.18Å; P472-C476 PolarHBondContact O-N 3.17Å
473	K	83.3	Confident	82.7	Confident	157 Å²	157	94.4 Å²	94.4	68%	0.683	46%	0.457	S	S	*	.	H	α-helix	trans	-53.9	-30.1	-176.3	-67.8	-177.2	179.9	178.4	0	113	R471 R477	R471-K473 PolarHBondContact O-N 3.08Å; R471-K473 VanDerWaalsContact O-N 3.07Å; K473-R477 WeakPolarHBondContact O-CB 3.2Å; K473-R477 VanDerWaalsContact O-CG 3.26Å; K473-R477 WeakPolarHBondContact O-CG 3.48Å; K473-R477 PolarHBondContact O-N 2.95Å
474	F	84.4	Confident	82.9	Confident	149 Å²	149	98.7 Å²	98.7	65%	0.654	47%	0.469	S	S	*	.	H	α-helix	trans	-63.3	-44.5	174.7	175.5	-101.4	0	0	0	112.5	P472 R477 L478	P472-F474 PolarHBondContact O-N 2.9Å; F474-R477 PolarHBondContact O-N 3.41Å; F474-L478 HydrophobicContact CE1-CD2 4.39Å; F474-L478 WeakPolarHBondContact O-CB 3.39Å; F474-L478 PolarHBondContact O-N 3.35Å
475	I	82.4	Confident	83.2	Confident	69 Å²	69	102.6 Å²	102.6	35%	0.354	48%	0.482	S	S	.	.	H	α-helix	trans	-65.5	-43.6	178.9	-63.7	176	0	0	0	110.1	V462 P472 R477 L478 N479	V462-I475 HydrophobicContact CG1-CD1 3.51Å; P472-I475 HydrophobicContact CB-CD1 4.04Å; P472-I475 HydrophobicContact CB-CG1 4.16Å; P472-I475 HydrophobicContact CG-CD1 3.92Å; P472-I475 PolarHBondContact O-N 3.18Å; I475-R477 PolarHBondContact O-N 3.26Å; I475-L478 PolarHBondContact O-N 3.02Å; I475-N479 WeakPolarHBondContact O-CB 3.38Å; I475-N479 PolarHBondContact O-N 2.89Å
476	C	81.3	Confident	83.3	Confident	54 Å²	54	96.1 Å²	96.1	37%	0.365	46%	0.46	S	S	.	.	H	α-helix	trans	-62.3	-43	176.7	-59.8	0	0	0	0	111.8	P472 N479 A480	P472-C476 PolarHBondContact O-N 3.17Å; C476-N479 PolarHBondContact O-N 2.74Å; C476-A480 WeakPolarHBondContact O-CB 3.41Å; C476-A480 PolarHBondContact O-N 2.95Å
477	R	85.1	Confident	83.5	Confident	175 Å²	175	97.1 Å²	97.1	66%	0.66	46%	0.463	S	S	*	.	H	α-helix	trans	-63.7	-42.9	174.9	-74.6	-179.8	-149.8	164.1	3.9	112.1	K473 F474 I475 A480 W481	K473-R477 WeakPolarHBondContact O-CB 3.2Å; K473-R477 VanDerWaalsContact O-CG 3.26Å; K473-R477 WeakPolarHBondContact O-CG 3.48Å; K473-R477 PolarHBondContact O-N 2.95Å; F474-R477 PolarHBondContact O-N 3.41Å; I475-R477 PolarHBondContact O-N 3.26Å; R477-A480 PolarHBondContact O-N 3.22Å; R477-W481 WeakPolarHBondContact O-CB 3.38Å; R477-W481 PolarHBondContact O-N 2.9Å
478	L	85.9	Confident	84.1	Confident	83 Å²	83	99.3 Å²	99.3	44%	0.435	47%	0.469	S	S	.	.	H	α-helix	trans	-62.9	-47.2	177.7	-178.8	64.8	0	0	0	110.6	F474 I475 A480 W481 V482	F474-L478 HydrophobicContact CE1-CD2 4.39Å; F474-L478 WeakPolarHBondContact O-CB 3.39Å; F474-L478 PolarHBondContact O-N 3.35Å; I475-L478 PolarHBondContact O-N 3.02Å; L478-A480 PolarHBondContact O-N 3.21Å; L478-W481 PolarHBondContact O-N 3.45Å; L478-V482 HydrophobicContact CD1-CG2 4.2Å; L478-V482 HydrophobicContact CG-CG2 4.39Å; L478-V482 WeakPolarHBondContact O-CB 3.22Å; L478-V482 VanDerWaalsContact O-CG2 3.3Å; L478-V482 WeakPolarHBondContact O-CG2 3.48Å; L478-V482 PolarHBondContact O-N 2.99Å
479	N	85.3	Confident	85	Confident	56 Å²	56	97.6 Å²	97.6	30%	0.299	47%	0.469	S	S	.	.	H	α-helix	trans	-61.5	-44.8	178.1	-171.2	22.9	0	0	0	111.5	I475 C476 W481 V482 T483	I475-N479 WeakPolarHBondContact O-CB 3.38Å; I475-N479 PolarHBondContact O-N 2.89Å; C476-N479 PolarHBondContact O-N 2.74Å; N479-W481 VanDerWaalsContact C-N 3.35Å; N479-W481 PolarHBondContact O-N 3.35Å; N479-V482 PolarHBondContact O-N 3.23Å; N479-T483 WeakPolarHBondContact O-CB 3.15Å; N479-T483 PolarHBondContact O-N 2.93Å; N479-T483 PolarHBondContact O-OG1 2.89Å
480	A	85.3	Confident	85.7	Confident	61 Å²	61	91.9 Å²	91.9	50%	0.504	44%	0.438	S	S	.	.	H	α-helix	trans	-64.4	-39.1	176	0	0	0	0	0	112.3	C476 R477 L478 K484	C476-A480 WeakPolarHBondContact O-CB 3.41Å; C476-A480 PolarHBondContact O-N 2.95Å; R477-A480 PolarHBondContact O-N 3.22Å; L478-A480 PolarHBondContact O-N 3.21Å; A480-K484 VanDerWaalsContact O-CB 3.29Å; A480-K484 WeakPolarHBondContact O-CB 3.47Å; A480-K484 PolarHBondContact O-N 3.23Å
481	W	88.2	Confident	86.2	Confident	138 Å²	138	89.5 Å²	89.5	52%	0.523	43%	0.43	S	S	.	.	H	α-helix	trans	-64.8	-52.1	176	-175	91.5	0	0	0	111	R477 L478 N479 T483 K484 Y485	R477-W481 WeakPolarHBondContact O-CB 3.38Å; R477-W481 PolarHBondContact O-N 2.9Å; L478-W481 PolarHBondContact O-N 3.45Å; N479-W481 VanDerWaalsContact C-N 3.35Å; N479-W481 PolarHBondContact O-N 3.35Å; W481-T483 VanDerWaalsContact C-N 3.34Å; W481-T483 PolarHBondContact O-N 2.85Å; W481-K484 PolarHBondContact O-N 3.41Å; W481-Y485 AromaticContact CD1-CD2 3.96Å; W481-Y485 AromaticContact CD1-CE2 3.57Å; W481-Y485 AromaticContact CD2-CD2 3.75Å; W481-Y485 HydrophobicContact CD2-CD2 3.75Å; W481-Y485 AromaticContact CD2-CE2 3.93Å; W481-Y485 HydrophobicContact CD2-CE2 3.93Å; W481-Y485 AromaticContact CE2-CD2 3.5Å; W481-Y485 VanDerWaalsContact CE2-CD2 3.5Å; W481-Y485 AromaticContact CE2-CE2 3.24Å; W481-Y485 AromaticContact CE2-CZ 3.87Å; W481-Y485 HydrophobicContact CE3-CD2 4.34Å; W481-Y485 HydrophobicContact CG-CD2 4.04Å; W481-Y485 HydrophobicContact CG-CE2 4.1Å; W481-Y485 HydrophobicContact CH2-CD2 4.44Å; W481-Y485 AromaticContact CZ2-CD2 3.87Å; W481-Y485 HydrophobicContact CZ2-CD2 3.87Å; W481-Y485 HydrophobicContact CZ2-CE1 4.28Å; W481-Y485 AromaticContact CZ2-CE2 3.64Å; W481-Y485 HydrophobicContact CZ2-CE2 3.64Å; W481-Y485 HydrophobicContact CZ2-CG 4.3Å; W481-Y485 AromaticContact CZ2-CZ 3.81Å; W481-Y485 AromaticContact NE1-CD2 3.67Å; W481-Y485 AromaticContact NE1-CE2 3.03Å; W481-Y485 AromaticContact NE1-CZ 3.75Å; W481-Y485 VanDerWaalsContact O-CD2 3.31Å; W481-Y485 WeakPolarHBondContact O-CD2 3.49Å; W481-Y485 PolarHBondContact O-N 3.15Å
482	V	87.4	Confident	86.3	Confident	51 Å²	51	86.9 Å²	86.9	31%	0.309	42%	0.422	S	S	.	.	H	α-helix	trans	-55.9	-50.9	176.3	170.4	0	0	0	0	109.8	L478 N479 K484 Y485 T486	L478-V482 HydrophobicContact CD1-CG2 4.2Å; L478-V482 HydrophobicContact CG-CG2 4.39Å; L478-V482 WeakPolarHBondContact O-CB 3.22Å; L478-V482 VanDerWaalsContact O-CG2 3.3Å; L478-V482 WeakPolarHBondContact O-CG2 3.48Å; L478-V482 PolarHBondContact O-N 2.99Å; N479-V482 PolarHBondContact O-N 3.23Å; V482-K484 PolarHBondContact O-N 3.28Å; V482-Y485 PolarHBondContact O-N 2.88Å; V482-T486 WeakPolarHBondContact O-CB 3.42Å; V482-T486 PolarHBondContact O-N 3.16Å; V482-T486 PolarHBondContact O-OG1 3.42Å
483	T	86.7	Confident	86.3	Confident	19 Å²	19	87.1 Å²	87.1	12%	0.117	42%	0.424	C	S	.	.	H	α-helix	trans	-52.8	-51.1	177.1	-66.2	0	0	0	0	111.2	M353 N479 W481 Y485 T486 Q487	M353-T483 HydrophobicContact CE-CG2 3.2Å; N479-T483 WeakPolarHBondContact O-CB 3.15Å; N479-T483 PolarHBondContact O-N 2.93Å; N479-T483 PolarHBondContact O-OG1 2.89Å; W481-T483 VanDerWaalsContact C-N 3.34Å; W481-T483 PolarHBondContact O-N 2.85Å; T483-Y485 PolarHBondContact O-N 3.4Å; T483-T486 PolarHBondContact O-N 2.71Å; T483-Q487 VanDerWaalsContact O-CG 3.28Å; T483-Q487 WeakPolarHBondContact O-CG 3.46Å; T483-Q487 PolarHBondContact O-N 3.09Å
484	K	87.9	Confident	86	Confident	126 Å²	126	82.8 Å²	82.8	55%	0.548	41%	0.408	S	S	.	.	H	α-helix	trans	-61.8	-44.7	179.2	-175.8	-178.6	179.7	-179.2	0	112.3	A480 W481 V482 Q487 I488	A480-K484 VanDerWaalsContact O-CB 3.29Å; A480-K484 WeakPolarHBondContact O-CB 3.47Å; A480-K484 PolarHBondContact O-N 3.23Å; W481-K484 PolarHBondContact O-N 3.41Å; V482-K484 PolarHBondContact O-N 3.28Å; K484-Q487 PolarHBondContact O-N 3.23Å; K484-I488 HydrophobicContact CG-CD1 3.88Å; K484-I488 VanDerWaalsContact O-CG1 3.27Å; K484-I488 WeakPolarHBondContact O-CG1 3.44Å; K484-I488 PolarHBondContact O-N 3.41Å
485	Y	89.6	Confident	85.1	Confident	114 Å²	114	77.2 Å²	77.2	45%	0.447	39%	0.386	S	S	.	.	H	α-helix	trans	-69	-39	179.4	-86.5	-95.6	0	0	0	112	W481 V482 T483 Q487 I488 V489	W481-Y485 AromaticContact CD1-CD2 3.96Å; W481-Y485 AromaticContact CD1-CE2 3.57Å; W481-Y485 AromaticContact CD2-CD2 3.75Å; W481-Y485 HydrophobicContact CD2-CD2 3.75Å; W481-Y485 AromaticContact CD2-CE2 3.93Å; W481-Y485 HydrophobicContact CD2-CE2 3.93Å; W481-Y485 AromaticContact CE2-CD2 3.5Å; W481-Y485 VanDerWaalsContact CE2-CD2 3.5Å; W481-Y485 AromaticContact CE2-CE2 3.24Å; W481-Y485 AromaticContact CE2-CZ 3.87Å; W481-Y485 HydrophobicContact CE3-CD2 4.34Å; W481-Y485 HydrophobicContact CG-CD2 4.04Å; W481-Y485 HydrophobicContact CG-CE2 4.1Å; W481-Y485 HydrophobicContact CH2-CD2 4.44Å; W481-Y485 AromaticContact CZ2-CD2 3.87Å; W481-Y485 HydrophobicContact CZ2-CD2 3.87Å; W481-Y485 HydrophobicContact CZ2-CE1 4.28Å; W481-Y485 AromaticContact CZ2-CE2 3.64Å; W481-Y485 HydrophobicContact CZ2-CE2 3.64Å; W481-Y485 HydrophobicContact CZ2-CG 4.3Å; W481-Y485 AromaticContact CZ2-CZ 3.81Å; W481-Y485 AromaticContact NE1-CD2 3.67Å; W481-Y485 AromaticContact NE1-CE2 3.03Å; W481-Y485 AromaticContact NE1-CZ 3.75Å; W481-Y485 VanDerWaalsContact O-CD2 3.31Å; W481-Y485 WeakPolarHBondContact O-CD2 3.49Å; W481-Y485 PolarHBondContact O-N 3.15Å; V482-Y485 PolarHBondContact O-N 2.88Å; T483-Y485 PolarHBondContact O-N 3.4Å; Y485-Q487 VanDerWaalsContact C-N 3.33Å; Y485-Q487 PolarHBondContact O-N 2.76Å; Y485-I488 PolarHBondContact O-N 3Å; Y485-V489 VanDerWaalsContact O-CB 3.28Å; Y485-V489 WeakPolarHBondContact O-CB 3.41Å; Y485-V489 VanDerWaalsContact O-CG2 3.26Å; Y485-V489 WeakPolarHBondContact O-CG2 3.37Å; Y485-V489 PolarHBondContact O-N 3.12Å
486	T	87.4	Confident	83.8	Confident	24 Å²	24	82.7 Å²	82.7	15%	0.147	41%	0.41	C	S	.	.	H	α-helix	trans	-58.2	-46.1	171.8	-58.3	0	0	0	0	110.6	M353 P363 V482 T483 I488 L490	M353-T486 HydrophobicContact SD-CG2 3.9Å; P363-T486 HydrophobicContact CB-CG2 3.91Å; P363-T486 HydrophobicContact CG-CG2 3.44Å; P363-T486 VanDerWaalsContact CG-CG2 3.44Å; V482-T486 WeakPolarHBondContact O-CB 3.42Å; V482-T486 PolarHBondContact O-N 3.16Å; V482-T486 PolarHBondContact O-OG1 3.42Å; T483-T486 PolarHBondContact O-N 2.71Å; T486-I488 PolarHBondContact O-N 2.75Å; T486-L490 HydrophobicContact CG2-CD1 3.87Å; T486-L490 VanDerWaalsContact O-CB 3.3Å; T486-L490 WeakPolarHBondContact O-CB 3.33Å; T486-L490 PolarHBondContact O-N 3.47Å
487	Q	87.8	Confident	82	Confident	72 Å²	72	85.4 Å²	85.4	34%	0.336	42%	0.421	S	S	.	.	H	α-helix	trans	-59.8	-45.3	176.7	-72.3	174.2	-24.5	0	0	112.4	M353 T483 K484 Y485 Y491 C492	M353-Q487 HydrophobicContact CE-CG 3.61Å; M353-Q487 HydrophobicContact SD-CG 3.6Å; M353-Q487 VanDerWaalsContact SD-CG 3.6Å; T483-Q487 VanDerWaalsContact O-CG 3.28Å; T483-Q487 WeakPolarHBondContact O-CG 3.46Å; T483-Q487 PolarHBondContact O-N 3.09Å; K484-Q487 PolarHBondContact O-N 3.23Å; Y485-Q487 VanDerWaalsContact C-N 3.33Å; Y485-Q487 PolarHBondContact O-N 2.76Å; Q487-Y491 WeakPolarHBondContact O-CA 3.45Å; Q487-Y491 PolarHBondContact O-N 2.99Å; Q487-C492 WeakPolarHBondContact CG-O 3.24Å; Q487-C492 PolarHBondContact O-N 2.84Å
488	I	88.3	Confident	79.8	Confident	114 Å²	114	84.1 Å²	84.1	59%	0.585	43%	0.427	S	S	*	.	H	α-helix	trans	-70.6	-48.5	-177.8	-66	166.5	0	0	0	111.4	K484 Y485 T486	K484-I488 HydrophobicContact CG-CD1 3.88Å; K484-I488 VanDerWaalsContact O-CG1 3.27Å; K484-I488 WeakPolarHBondContact O-CG1 3.44Å; K484-I488 PolarHBondContact O-N 3.41Å; Y485-I488 PolarHBondContact O-N 3Å; T486-I488 PolarHBondContact O-N 2.75Å
489	V	90.8	Very high	77.3	Confident	110 Å²	110	85.4 Å²	85.4	67%	0.667	44%	0.438	S	S	*	.	H	α-helix	trans	-73.9	-40.2	-173	174.1	0	0	0	0	111.5	Y485	Y485-V489 VanDerWaalsContact O-CB 3.28Å; Y485-V489 WeakPolarHBondContact O-CB 3.41Å; Y485-V489 VanDerWaalsContact O-CG2 3.26Å; Y485-V489 WeakPolarHBondContact O-CG2 3.37Å; Y485-V489 PolarHBondContact O-N 3.12Å
490	L	88.1	Confident	74.8	Confident	42 Å²	42	91 Å²	91	22%	0.22	46%	0.462	C	S	.	.	H	α-helix	trans	-101.4	1.2	-174.4	-57.4	175.5	0	0	0	113.2	V362 P363 I366 T486 C492	V362-L490 HydrophobicContact CG1-CD1 4.16Å; V362-L490 HydrophobicContact CG1-CD2 4.16Å; P363-L490 HydrophobicContact CB-CD1 4.44Å; P363-L490 HydrophobicContact CG-CD1 3.89Å; I366-L490 HydrophobicContact CD1-CD1 4.12Å; I366-L490 HydrophobicContact CD1-CD2 4.09Å; T486-L490 HydrophobicContact CG2-CD1 3.87Å; T486-L490 VanDerWaalsContact O-CB 3.3Å; T486-L490 WeakPolarHBondContact O-CB 3.33Å; T486-L490 PolarHBondContact O-N 3.47Å; L490-C492 VanDerWaalsContact C-N 3.27Å; L490-C492 VanDerWaalsContact CB-SG 3.51Å; L490-C492 PolarHBondContact O-N 2.89Å; L490-C492 PolarHBondContact O-SG 2.9Å
491	Y	88.8	Confident	72.2	Confident	142 Å²	142	93.5 Å²	93.5	56%	0.557	47%	0.473	S	S	*	.	T	Hydrogen-bonded Turn	trans	49	50.4	-177.3	-162.7	-114.2	0	0	0	112.1	A356 E357 Q487	A356-Y491 HydrophobicContact CB-CD1 3.87Å; A356-Y491 HydrophobicContact CB-CE1 3.74Å; A356-Y491 PolarHBondContact N-O 2.87Å; E357-Y491 HydrophobicContact CG-CD1 4.36Å; E357-Y491 HydrophobicContact CG-CE1 4.17Å; Q487-Y491 WeakPolarHBondContact O-CA 3.45Å; Q487-Y491 PolarHBondContact O-N 2.99Å
492	C	85.7	Confident	69.4	Low	10 Å²	10	95.7 Å²	95.7	7%	0.068	49%	0.489	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-108	148.7	-175.8	-65.2	0	0	0	0	111.7	M353 I354 Q487 L490	M353-C492 HydrophobicContact CB-CB 3.79Å; M353-C492 HydrophobicContact SD-CB 4.27Å; I354-C492 CarbonylContact O-C 3.23Å; I354-C492 WeakPolarHBondContact O-CA 3.47Å; I354-C492 WeakPolarHBondContact O-CB 3.23Å; Q487-C492 WeakPolarHBondContact CG-O 3.24Å; Q487-C492 PolarHBondContact O-N 2.84Å; L490-C492 VanDerWaalsContact C-N 3.27Å; L490-C492 VanDerWaalsContact CB-SG 3.51Å; L490-C492 PolarHBondContact O-N 2.89Å; L490-C492 PolarHBondContact O-SG 2.9Å
493	C	82	Confident	66.6	Low	63 Å²	63	102.9 Å²	102.9	43%	0.426	52%	0.516	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-120.5	153.7	173.4	54.3	0	0	0	0	110.8	M353 I354	M353-C493 WeakPolarHBondContact CA-O 3.17Å; I354-C493 PolarHBondContact N-O 2.79Å; I354-C493 PolarHBondContact O-N 2.81Å
494	L	77.2	Confident	63.8	Low	66 Å²	66	112.6 Å²	112.6	35%	0.346	55%	0.551	S	S	.	*	E	Extended strand (participates in β ladder)	trans	-71.7	138.8	167	-92.2	126.4	0	0	0	108.6	N349 M353	N349-L494 HydrophobicContact CB-CD2 4.22Å; M353-L494 HydrophobicContact CE-CD1 4.1Å; M353-L494 HydrophobicContact CG-CG 4.3Å
495	T	66.8	Low	61	Low	33 Å²	33	115.6 Å²	115.6	20%	0.202	57%	0.567	C	S	.	*	P	Polyproline II helix	trans	-71.1	140.2	165.6	46	0	0	0	0	108.7	F339 R343 I354 L497	F339-T495 HydrophobicContact CE2-CG2 4.41Å; F339-T495 HydrophobicContact CZ-CG2 4.12Å; F339-T495 WeakPolarHBondContact CZ-OG1 3.33Å; R343-T495 PolarHBondContact NE-OG1 2.82Å; R343-T495 VanDerWaalsContact NH2-CB 3.26Å; R343-T495 PolarHBondContact NH2-OG1 2.97Å; I354-T495 HydrophobicContact CB-CG2 4.5Å; I354-T495 HydrophobicContact CD1-CG2 3.32Å; I354-T495 HydrophobicContact CG1-CG2 3.84Å; T495-L497 PolarHBondContact O-N 2.9Å
496	E	54.3	Low	58.2	Low	184 Å²	184	116.8 Å²	116.8	86%	0.86	58%	0.581	S	S	*	*	P	Polyproline II helix	trans	-54.1	128.3	174	-71.5	-177.9	165.6	0	0	108.7	D498	E496-D498 PolarHBondContact O-N 2.8Å
497	L	44.1	Very low	55.5	Low	110 Å²	110	120.9 Å²	120.9	58%	0.576	61%	0.611	S	S	*	*	P	Polyproline II helix	trans	-68.3	126.5	174.8	-77.6	150.9	0	0	0	106.9	T495 V499	T495-L497 PolarHBondContact O-N 2.9Å; L497-V499 HydrophobicContact CB-CG2 3.7Å; L497-V499 PolarHBondContact O-N 3.47Å
498	D	37.4	Very low	52.7	Low	149 Å²	149	127 Å²	127	80%	0.797	64%	0.636	S	S	*	*			trans	-66.5	74.4	163.7	-70.4	-47.8	0	0	0	107.9	E496 E500	E496-D498 PolarHBondContact O-N 2.8Å; D498-E500 PolarHBondContact O-N 3.21Å; D498-E500 VanDerWaalsContact O-N 3.16Å
499	V	35	Very low	50.1	Low	109 Å²	109	125.7 Å²	125.7	66%	0.661	64%	0.642	S	S	*	*			trans	-76.5	101.5	172.3	-174.9	0	0	0	0	105.7	L497 P501	L497-V499 HydrophobicContact CB-CG2 3.7Å; L497-V499 PolarHBondContact O-N 3.47Å; V499-P501 VanDerWaalsContact O-CD 3.28Å; V499-P501 WeakPolarHBondContact O-CD 3.28Å; V499-P501 VanDerWaalsContact O-N 3.14Å
500	E	31.6	Very low	47.3	Very low	174 Å²	174	133 Å²	133	81%	0.813	67%	0.669	S	S	*	*			trans	-54.7	119	159.4	-77.4	-171	157.8	0	0	106.7	D498 E502	D498-E500 PolarHBondContact O-N 3.21Å; D498-E500 VanDerWaalsContact O-N 3.16Å; E500-E502 PolarHBondContact O-N 3.1Å
501	P	30.8	Very low	45.3	Very low	113 Å²	113	137.5 Å²	137.5	73%	0.734	69%	0.691	S	S	*	*			trans	-64	115.2	174.6	24.2	-29	0	0	0	106.8	V499 K503	V499-P501 VanDerWaalsContact O-CD 3.28Å; V499-P501 WeakPolarHBondContact O-CD 3.28Å; V499-P501 VanDerWaalsContact O-N 3.14Å; P501-K503 PolarHBondContact O-N 3.44Å
502	E	29.6	Very low	43	Very low	185 Å²	185	137.3 Å²	137.3	86%	0.864	70%	0.698	S	S	*	*			trans	-42.7	117.6	163.2	-91.6	-177.7	150.6	0	0	107.1	E500 R504	E500-E502 PolarHBondContact O-N 3.1Å; E502-R504 VanDerWaalsContact C-N 3.25Å; E502-R504 PolarHBondContact O-N 3.5Å
503	K	28.9	Very low	40.6	Very low	201 Å²	201	144.3 Å²	144.3	87%	0.874	73%	0.733	S	S	*	*			trans	-57.2	99.4	167.1	-83.6	178.9	175.3	175.9	0	106.3	P501 E505	P501-K503 PolarHBondContact O-N 3.44Å; K503-E505 VanDerWaalsContact C-N 3.3Å; K503-E505 PolarHBondContact O-N 3.37Å
504	R	27.3	Very low	38.1	Very low	224 Å²	224	149.1 Å²	149.1	85%	0.845	75%	0.752	S	S	*	*			trans	-56.1	104.2	158.1	-86.3	-176.8	175.7	-178.5	-0.6	105.6	E502 D506	E502-R504 VanDerWaalsContact C-N 3.25Å; E502-R504 PolarHBondContact O-N 3.5Å; R504-D506 PolarHBondContact O-N 3.28Å
505	E	30.4	Very low	35.7	Very low	189 Å²	189	154.3 Å²	154.3	88%	0.883	78%	0.777	S	S	*	*			trans	-60.5	96.8	158.9	-76.2	-173.5	155.5	0	0	106.2	K503 S507	K503-E505 VanDerWaalsContact C-N 3.3Å; K503-E505 PolarHBondContact O-N 3.37Å; E505-S507 VanDerWaalsContact C-N 3.26Å; E505-S507 PolarHBondContact O-N 3.17Å
506	D	29.7	Very low	33.6	Very low	139 Å²	139	162.4 Å²	162.4	74%	0.743	82%	0.815	S	S	*	*			trans	-61	98	164	-80.2	-27.6	0	0	0	107	R504 K508	R504-D506 PolarHBondContact O-N 3.28Å; D506-K508 PolarHBondContact O-N 3.15Å
507	S	30.6	Very low	32.2	Very low	110 Å²	110	160.9 Å²	160.9	77%	0.769	81%	0.812	S	S	*	*			trans	-51.8	93	157.3	162.7	0	0	0	0	107.9	E505 A509	E505-S507 VanDerWaalsContact C-N 3.26Å; E505-S507 PolarHBondContact O-N 3.17Å; S507-A509 VanDerWaalsContact C-N 3.28Å; S507-A509 PolarHBondContact O-N 3.45Å
508	K	30.4	Very low	31.2	Very low	200 Å²	200	164.8 Å²	164.8	87%	0.87	83%	0.83	S	S	*	*			trans	-65.9	92.5	165	-78	-174.4	175.8	-178.6	0	108.5	D506	D506-K508 PolarHBondContact O-N 3.15Å
509	A	32.9	Very low	30.7	Very low	86 Å²	86	166.1 Å²	166.1	71%	0.711	83%	0.833	S	S	*	*			trans	-88.5	97.4	150.5	0	0	0	0	0	107.6	S507	S507-A509 VanDerWaalsContact C-N 3.28Å; S507-A509 PolarHBondContact O-N 3.45Å
510	Q	31.6	Very low	30.3	Very low	263 Å²	263	171.3 Å²	171.3	100%	1.229	85%	0.849	S	S	*	*			trans	-176.3	0	138.9	-106.1	177.9	-6.5	0	0	110.2

Retrieved 510 of 510 residues in 2304.5 ms (Link to these results)

U.S. Privacy Notice - Disclaimer / Registrations / Copyright Statement - Linking Policy - Notice of Privacy Practices (HIPAA) - Notice of Non‑Discrimination
© Copyright 2026 St. Jude Children's Research Hospital, a not-for-profit, section 501(c)(3).