A0A060VVF8_ONCMY Loading...

Type-1 angiotensin II receptor

Receptor for angiotensin II, a vasoconstricting peptide, which acts as a key regulator of blood pressure and sodium retention by the kidney. The activated receptor in turn couples to G-alpha proteins G(q) (GNAQ, GNA11, GNA14 or GNA15) and thus activates phospholipase C and increases the cytosolic Ca(2+) concentrations, which in turn triggers cellular responses such as stimulation of protein kinase C. Receptor for angiotensin II, a vasoconstricting peptide, which acts as a key regulator of blood pressure and sodium retention by the kidney. The activated receptor in turn couples to G-alpha proteins G(q) and thus activates phospholipase C and increases the cytosolic Ca(2+) concentrations, which in turn triggers cellular responses such as stimulation of protein kinase C.

AlphaFold DB , UniProt , Accession A0A060VVF8, Species ONCMY (Oncorhynchus mykiss, Rainbow trout), Gene agtr2, Length 369 aa.

Structure Viewer

Loading PAE data...

(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	33.1	Very low	29.1	Very low	60 Å²	60	81.6 Å²	81.6	30%	0.296	49%	0.486	S	S	.	.				0	-12.8	0	-119.8	169.4	-174	0	0	114.7	S3 Y95 Y99 P293	M1-S3 VanDerWaalsContact C-N 3.34Å; M1-Y95 HydrophobicContact CE-CE1 4.27Å; M1-Y95 HydrophobicContact SD-CE1 3.62Å; M1-Y95 PolarHBondContact SD-OH 3.42Å; M1-Y99 HydrophobicContact CE-CE1 3.54Å; M1-Y99 VanDerWaalsContact CE-OH 3.31Å; M1-Y99 WeakPolarHBondContact CE-OH 2.96Å; M1-Y99 HydrophobicContact SD-CE1 3.75Å; M1-P293 HydrophobicContact CE-CB 4.08Å; M1-P293 HydrophobicContact CE-CG 3.28Å; M1-P293 HydrophobicContact CG-CG 4.39Å; M1-P293 HydrophobicContact SD-CB 4.12Å; M1-P293 HydrophobicContact SD-CG 3.68Å
2	A	25.7	Very low	29	Very low	20 Å²	20	86.2 Å²	86.2	17%	0.165	52%	0.515	C	S	.	.			trans	-81.1	-10.7	168.5	0	0	0	0	0	113.9	L189	A2-L189 HydrophobicContact CB-CB 3.91Å; A2-L189 HydrophobicContact CB-CD1 4.05Å; A2-L189 HydrophobicContact CB-CG 4.25Å
3	S	28.4	Very low	28.9	Very low	18 Å²	18	92.3 Å²	92.3	13%	0.126	54%	0.544	C	S	.	.	S	Bend	trans	-91.2	-10.7	179.9	44.7	0	0	0	0	114.4	M1 S6 D271	M1-S3 VanDerWaalsContact C-N 3.34Å; S3-S6 PolarHBondContact O-OG 2.73Å; S3-D271 WeakPolarHBondContact CB-OD2 3.49Å; S3-D271 PolarHBondContact OG-OD2 3.45Å
4	T	34.3	Very low	28.9	Very low	57 Å²	57	94.6 Å²	94.6	35%	0.35	57%	0.567	S	S	.	*	S	Bend	trans	-86.5	-14.8	-175.5	-30.2	0	0	0	0	113.3	I289	T4-I289 HydrophobicContact CG2-CD1 4.03Å; T4-I289 HydrophobicContact CG2-CG1 3.84Å; T4-I289 HydrophobicContact CG2-CG2 4.19Å
5	H	33.4	Very low	29	Very low	72 Å²	72	95.7 Å²	95.7	33%	0.333	58%	0.581	S	S	.	*	S	Bend	trans	-106.1	-1.1	-179.4	-71.7	-66.1	0	0	0	114.7	N7 L179	H5-N7 PolarHBondContact O-N 3.3Å; H5-L179 HydrophobicContact CB-CD2 4.38Å; H5-L179 VanDerWaalsContact CE1-CD2 3.48Å; H5-L179 WeakPolarHBondContact CE1-CD2 3.26Å; H5-L179 WeakPolarHBondContact ND1-CD2 3.37Å
6	S	29.5	Very low	29	Very low	79 Å²	79	101.3 Å²	101.3	55%	0.552	60%	0.599	S	S	*	*	T	Hydrogen-bonded Turn	trans	-77.8	-2.4	175.8	53.9	0	0	0	0	114.3	S3	S3-S6 PolarHBondContact O-OG 2.73Å
7	N	27.2	Very low	28.9	Very low	113 Å²	113	104.2 Å²	104.2	60%	0.604	61%	0.611	S	S	*	*	T	Hydrogen-bonded Turn	trans	-112.1	12.4	-177.3	-71.9	9.3	0	0	0	114.1	H5	H5-N7 PolarHBondContact O-N 3.3Å
8	L	26.6	Very low	28.8	Very low	88 Å²	88	106.5 Å²	106.5	46%	0.461	62%	0.62	S	S	.	*			trans	-103.6	44.9	-178.6	-156.3	68.7	0	0	0	111.8	E181	L8-E181 VanDerWaalsContact CD2-CD 3.46Å; L8-E181 HydrophobicContact CD2-CG 4.44Å; L8-E181 WeakPolarHBondContact CD2-OE2 3.31Å; L8-E181 WeakPolarHBondContact CG-OE1 3.3Å; L8-E181 WeakPolarHBondContact CG-OE2 3.09Å
9	S	27.3	Very low	28.6	Very low	95 Å²	95	109.7 Å²	109.7	66%	0.664	63%	0.63	S	S	*	*			trans	-150.9	78.1	173	66.8	0	0	0	0	110.8
10	M	28.1	Very low	29.2	Very low	195 Å²	195	113.1 Å²	113.1	96%	0.961	64%	0.644	S	S	*	*			trans	178.6	89.3	149.8	-102.8	174.9	-155.6	0	0	109
11	A	27	Very low	29.3	Very low	101 Å²	101	114.9 Å²	114.9	84%	0.835	65%	0.652	S	S	*	*			trans	-151.8	91.5	157.4	0	0	0	0	0	108.4
12	T	27.8	Very low	29.5	Very low	136 Å²	136	116.8 Å²	116.8	83%	0.834	67%	0.671	S	S	*	*			trans	-132.5	109.3	164.5	44.9	0	0	0	0	109.4
13	N	27.5	Very low	30.2	Very low	166 Å²	166	120.9 Å²	120.9	89%	0.888	70%	0.698	S	S	*	*			trans	36.1	120	153.7	-65.7	-3.1	0	0	0	121.6
14	S	28.3	Very low	31.3	Very low	124 Å²	124	124.2 Å²	124.2	87%	0.867	72%	0.722	S	S	*	*				-166.7	146.7	117.6	55.6	0	0	0	0	111.5
15	S	30.4	Very low	32.7	Very low	112 Å²	112	123.3 Å²	123.3	78%	0.783	72%	0.718	S	S	*	*			trans	-74.8	162.3	-168.4	-19.3	0	0	0	0	115.9
16	E	29.6	Very low	33.8	Very low	184 Å²	184	126.9 Å²	126.9	86%	0.86	74%	0.739	S	S	*	*			trans	83.4	102.3	156.4	-70.5	178.8	161.2	0	0	120.9
17	D	28.3	Very low	34.9	Very low	152 Å²	152	128 Å²	128	81%	0.813	75%	0.747	S	S	*	*			trans	59.9	135.1	141.3	-75.3	-17.1	0	0	0	125.1
18	L	26.8	Very low	36	Very low	145 Å²	145	128.1 Å²	128.1	76%	0.759	75%	0.746	S	S	*	*			trans	94.6	122.4	155.1	-83.9	139.4	0	0	0	120.5
19	M	24.9	Very low	37.2	Very low	167 Å²	167	128.2 Å²	128.2	82%	0.823	75%	0.754	S	S	*	*			trans	93.8	95	162	-55.8	-61.3	-179.5	0	0	117.3	N21	M19-N21 PolarHBondContact O-N 3.38Å; M19-N21 VanDerWaalsContact O-N 3.1Å
20	I	39.3	Very low	38.5	Very low	177 Å²	177	128 Å²	128	91%	0.908	75%	0.75	S	S	*	*			trans	-30.9	103.1	155.6	-58.3	166.4	0	0	0	111.6
21	N	32.3	Very low	39.9	Very low	152 Å²	152	121.2 Å²	121.2	81%	0.813	72%	0.722	S	S	*	*			trans	-164.8	77.3	142.8	-146.3	11.6	0	0	0	111.2	M19	M19-N21 PolarHBondContact O-N 3.38Å; M19-N21 VanDerWaalsContact O-N 3.1Å
22	S	36.7	Very low	41.4	Very low	100 Å²	100	123.4 Å²	123.4	70%	0.699	72%	0.719	S	S	*	*			trans	-122	94.6	165.4	51.1	0	0	0	0	109.2	S24	S22-S24 PolarHBondContact O-N 3.49Å
23	S	41.9	Very low	43.5	Very low	105 Å²	105	123.5 Å²	123.5	73%	0.734	71%	0.71	S	S	*	*			trans	-69.7	60	161.9	47.1	0	0	0	0	110	C25	S23-C25 PolarHBondContact O-N 2.97Å; S23-C25 VanDerWaalsContact O-N 3.09Å
24	S	51.4	Low	46.1	Very low	89 Å²	89	116.1 Å²	116.1	62%	0.622	67%	0.67	S	S	*	*			trans	-70	102.3	169.1	-66.1	0	0	0	0	107.1	S22 D26	S22-S24 PolarHBondContact O-N 3.49Å; S24-D26 PolarHBondContact O-N 3.08Å
25	C	62.8	Low	48.8	Very low	38 Å²	38	111.6 Å²	111.6	26%	0.257	64%	0.636	S	S	.	*			trans	-60.4	110.4	172	-45.8	0	0	0	0	107.5	S23 S27 C282	S23-C25 PolarHBondContact O-N 2.97Å; S23-C25 VanDerWaalsContact O-N 3.09Å; C25-S27 PolarHBondContact O-N 3.21Å; C25-C282 HydrophobicContact CB-CB 3.85Å; C25-C282 WeakPolarHBondContact CB-SG 3.4Å; C25-C282 WeakPolarHBondContact SG-CA 3.34Å; C25-C282 WeakPolarHBondContact SG-CB 3.45Å; C25-C282 CovalentContact SG-SG 2.05Å; C25-C282 PolarHBondContact SG-SG 3.35Å
26	D	55.9	Low	51.5	Low	146 Å²	146	114 Å²	114	78%	0.781	63%	0.633	S	S	*	*			trans	-55.7	115	176.9	-73.6	-34.2	0	0	0	109.7	S24 I28	S24-D26 PolarHBondContact O-N 3.08Å; D26-I28 PolarHBondContact O-N 3.03Å; D26-I28 VanDerWaalsContact O-N 3.15Å
27	S	53.4	Low	54.5	Low	102 Å²	102	109.1 Å²	109.1	71%	0.713	61%	0.612	S	S	*	*			trans	-72.3	105.1	175.5	51.9	0	0	0	0	109.1	C25 S29	C25-S27 PolarHBondContact O-N 3.21Å; S27-S29 PolarHBondContact O-N 3.2Å
28	I	50.7	Low	57.5	Low	117 Å²	117	101.9 Å²	101.9	60%	0.6	57%	0.573	S	S	*	*	P	Polyproline II helix	trans	-62.7	120.8	166.8	-59.4	174.1	0	0	0	107.3	D26	D26-I28 PolarHBondContact O-N 3.03Å; D26-I28 VanDerWaalsContact O-N 3.15Å
29	S	51.7	Low	60.8	Low	90 Å²	90	95.6 Å²	95.6	63%	0.629	54%	0.541	S	S	*	.	P	Polyproline II helix	trans	-48.6	137.7	175.4	51	0	0	0	0	111	S27 S31	S27-S29 PolarHBondContact O-N 3.2Å; S29-S31 PolarHBondContact O-N 2.74Å
30	P	54.6	Low	64.1	Low	89 Å²	89	91.7 Å²	91.7	58%	0.578	53%	0.527	S	S	*	.	P	Polyproline II helix	trans	-51.6	120.1	173.5	12.8	-20.4	0	0	0	108.8	L32	P30-L32 PolarHBondContact O-N 3.28Å
31	S	57.6	Low	66.8	Low	53 Å²	53	85.5 Å²	85.5	37%	0.371	50%	0.495	S	S	.	.	P	Polyproline II helix	trans	-56.1	132.2	-173.4	59.6	0	0	0	0	109.5	S29 H33 Q34	S29-S31 PolarHBondContact O-N 2.74Å; S31-H33 PolarHBondContact O-N 3.05Å; S31-Q34 PolarHBondContact O-N 2.93Å
32	L	57.7	Low	69.9	Low	147 Å²	147	78.3 Å²	78.3	77%	0.77	46%	0.456	S	S	*	.	T	Hydrogen-bonded Turn	trans	-44.9	-21.8	177.2	-174.1	66.8	0	0	0	114.2	P30	P30-L32 PolarHBondContact O-N 3.28Å
33	H	72.4	Confident	72.8	Confident	139 Å²	139	76.5 Å²	76.5	64%	0.644	44%	0.444	S	S	*	.	T	Hydrogen-bonded Turn	trans	-75	-21.2	177.7	-59	-64.5	0	0	0	115.2	S31 N35 K36 L37	S31-H33 PolarHBondContact O-N 3.05Å; H33-N35 PolarHBondContact O-N 3.47Å; H33-K36 PolarHBondContact O-N 3.46Å; H33-L37 VanDerWaalsContact O-CB 3.24Å; H33-L37 WeakPolarHBondContact O-CB 3.37Å; H33-L37 PolarHBondContact O-N 2.87Å
34	Q	81.4	Confident	75.4	Confident	10 Å²	10	75.1 Å²	75.1	5%	0.047	43%	0.431	C	S	.	.	H	α-helix	trans	-64	-39.6	-176.5	-76.1	-178.8	0.7	0	0	112.3	S31 K36 L37 I38 Y99 F294	S31-Q34 PolarHBondContact O-N 2.93Å; Q34-K36 PolarHBondContact O-N 3.08Å; Q34-L37 PolarHBondContact O-N 3.29Å; Q34-I38 HydrophobicContact CB-CD1 3.99Å; Q34-I38 HydrophobicContact CG-CD1 4.28Å; Q34-I38 WeakPolarHBondContact O-CB 3.33Å; Q34-I38 WeakPolarHBondContact O-CG1 3.42Å; Q34-I38 PolarHBondContact O-N 3.46Å; Q34-Y99 PolarHBondContact OE1-OH 3.33Å; Q34-F294 HydrophobicContact CG-CZ 4.16Å
35	N	84.1	Confident	77.6	Confident	29 Å²	29	71.2 Å²	71.2	16%	0.155	40%	0.403	C	S	.	.	H	α-helix	trans	-72.3	-9.8	-176.5	-56.7	-10.9	0	0	0	112.9	H33 P39 Y95 D98 Y99	H33-N35 PolarHBondContact O-N 3.47Å; N35-P39 VanDerWaalsContact O-CG 3.31Å; N35-P39 WeakPolarHBondContact O-CG 3.48Å; N35-Y95 WeakPolarHBondContact CA-O 3.45Å; N35-Y95 WeakPolarHBondContact CB-O 3.22Å; N35-D98 PolarHBondContact ND2-OD1 2.92Å; N35-Y99 VanDerWaalsContact OD1-CE2 3.29Å; N35-Y99 WeakPolarHBondContact OD1-CE2 3.36Å
36	K	88.3	Confident	79.3	Confident	164 Å²	164	72.2 Å²	72.2	71%	0.713	40%	0.403	S	S	*	.	H	α-helix	trans	-105.9	-43.6	171.5	-65.7	-177	179.7	-179.8	0	112	H33 Q34 T40	H33-K36 PolarHBondContact O-N 3.46Å; Q34-K36 PolarHBondContact O-N 3.08Å; K36-T40 WeakPolarHBondContact O-CB 3.34Å; K36-T40 PolarHBondContact O-N 3.27Å; K36-T40 PolarHBondContact O-OG1 2.99Å
37	L	91.4	Very high	81.2	Confident	80 Å²	80	69.2 Å²	69.2	42%	0.419	39%	0.389	S	S	.	.	H	α-helix	trans	-71.2	-46.6	-174.2	-178.1	57.7	0	0	0	112.5	H33 Q34 T40 I41 F294	H33-L37 VanDerWaalsContact O-CB 3.24Å; H33-L37 WeakPolarHBondContact O-CB 3.37Å; H33-L37 PolarHBondContact O-N 2.87Å; Q34-L37 PolarHBondContact O-N 3.29Å; L37-T40 WeakPolarHBondContact O-CB 3.37Å; L37-T40 PolarHBondContact O-N 3.36Å; L37-I41 HydrophobicContact CD1-CD1 3.95Å; L37-I41 HydrophobicContact CD1-CG1 4.26Å; L37-I41 HydrophobicContact CG-CD1 3.9Å; L37-I41 WeakPolarHBondContact O-CG1 3.47Å; L37-I41 PolarHBondContact O-N 2.96Å; L37-F294 HydrophobicContact CD2-CE1 3.81Å; L37-F294 HydrophobicContact CD2-CZ 4.48Å
38	I	92.9	Very high	83.3	Confident	0 Å²	0	68.2 Å²	68.2	0%	0	38%	0.376	C	S	.	.	H	α-helix	trans	-63.6	-48.9	-177.6	-63.6	170.2	0	0	0	111.3	Q34 T40 I41 Y42 Y95 P293	Q34-I38 HydrophobicContact CB-CD1 3.99Å; Q34-I38 HydrophobicContact CG-CD1 4.28Å; Q34-I38 WeakPolarHBondContact O-CB 3.33Å; Q34-I38 WeakPolarHBondContact O-CG1 3.42Å; Q34-I38 PolarHBondContact O-N 3.46Å; I38-T40 VanDerWaalsContact C-N 3.29Å; I38-T40 PolarHBondContact O-N 3.03Å; I38-I41 PolarHBondContact O-N 3.49Å; I38-Y42 HydrophobicContact CG2-CD1 4.32Å; I38-Y42 HydrophobicContact CG2-CD2 4.14Å; I38-Y42 HydrophobicContact CG2-CE1 3.94Å; I38-Y42 HydrophobicContact CG2-CE2 3.73Å; I38-Y42 HydrophobicContact CG2-CG 4.41Å; I38-Y42 PolarHBondContact O-N 2.77Å; I38-Y95 HydrophobicContact CB-CD1 4.17Å; I38-Y95 HydrophobicContact CB-CG 4.26Å; I38-Y95 HydrophobicContact CD1-CD1 3.76Å; I38-Y95 HydrophobicContact CD1-CE1 3.68Å; I38-Y95 HydrophobicContact CG2-CD1 3.82Å; I38-Y95 HydrophobicContact CG2-CD2 3.77Å; I38-Y95 HydrophobicContact CG2-CE1 4.04Å; I38-Y95 HydrophobicContact CG2-CE2 4.09Å; I38-Y95 HydrophobicContact CG2-CG 3.67Å; I38-P293 HydrophobicContact CD1-CB 3.63Å
39	P	94.6	Very high	85.4	Confident	13 Å²	13	62.6 Å²	62.6	8%	0.084	35%	0.347	C	S	.	.	H	α-helix	trans	-58	-41	175.2	-26.3	36.1	0	0	0	112.8	N35 I41 Y42 S43 A92	N35-P39 VanDerWaalsContact O-CG 3.31Å; N35-P39 WeakPolarHBondContact O-CG 3.48Å; P39-I41 PolarHBondContact O-N 3Å; P39-Y42 PolarHBondContact O-N 3.37Å; P39-S43 PolarHBondContact O-N 3.42Å; P39-S43 PolarHBondContact O-OG 3.39Å; P39-S43 VanDerWaalsContact O-OG 3.07Å; P39-A92 HydrophobicContact CB-CB 4.25Å; P39-A92 WeakPolarHBondContact CG-O 3.48Å
40	T	95.3	Very high	87.6	Confident	85 Å²	85	61.3 Å²	61.3	52%	0.521	33%	0.33	S	S	.	.	H	α-helix	trans	-59.9	-46.7	177.8	-58.3	0	0	0	0	111.2	K36 L37 I38 Y42 S43 V44	K36-T40 WeakPolarHBondContact O-CB 3.34Å; K36-T40 PolarHBondContact O-N 3.27Å; K36-T40 PolarHBondContact O-OG1 2.99Å; L37-T40 WeakPolarHBondContact O-CB 3.37Å; L37-T40 PolarHBondContact O-N 3.36Å; I38-T40 VanDerWaalsContact C-N 3.29Å; I38-T40 PolarHBondContact O-N 3.03Å; T40-Y42 PolarHBondContact O-N 2.98Å; T40-S43 PolarHBondContact O-N 3.35Å; T40-V44 WeakPolarHBondContact O-CG2 3.46Å; T40-V44 PolarHBondContact O-N 2.83Å
41	I	96.1	Very high	89.5	Confident	47 Å²	47	61.7 Å²	61.7	24%	0.241	33%	0.33	C	S	.	.	H	α-helix	trans	-61.7	-45	176.8	-66.3	165.1	0	0	0	110.5	L37 I38 P39 S43 V44 I45 C297	L37-I41 HydrophobicContact CD1-CD1 3.95Å; L37-I41 HydrophobicContact CD1-CG1 4.26Å; L37-I41 HydrophobicContact CG-CD1 3.9Å; L37-I41 WeakPolarHBondContact O-CG1 3.47Å; L37-I41 PolarHBondContact O-N 2.96Å; I38-I41 PolarHBondContact O-N 3.49Å; P39-I41 PolarHBondContact O-N 3Å; I41-S43 VanDerWaalsContact C-N 3.35Å; I41-S43 PolarHBondContact O-N 2.86Å; I41-V44 PolarHBondContact O-N 2.86Å; I41-I45 HydrophobicContact CG2-CD1 3.66Å; I41-I45 HydrophobicContact CG2-CG1 4.27Å; I41-I45 VanDerWaalsContact O-CG1 3.28Å; I41-I45 WeakPolarHBondContact O-CG1 3.38Å; I41-I45 PolarHBondContact O-N 3.09Å; I41-C297 HydrophobicContact CG2-CB 3.95Å
42	Y	96.8	Very high	91.2	Very high	2 Å²	2	59.8 Å²	59.8	1%	0.008	32%	0.32	C	S	.	.	H	α-helix	trans	-62.4	-39.6	178	-75.3	4.9	0	0	0	112.6	I38 P39 T40 I45 F46 L88 W91 A92 Y95 C297 F300	I38-Y42 HydrophobicContact CG2-CD1 4.32Å; I38-Y42 HydrophobicContact CG2-CD2 4.14Å; I38-Y42 HydrophobicContact CG2-CE1 3.94Å; I38-Y42 HydrophobicContact CG2-CE2 3.73Å; I38-Y42 HydrophobicContact CG2-CG 4.41Å; I38-Y42 PolarHBondContact O-N 2.77Å; P39-Y42 PolarHBondContact O-N 3.37Å; T40-Y42 PolarHBondContact O-N 2.98Å; Y42-I45 HydrophobicContact CD1-CD1 4.46Å; Y42-I45 PolarHBondContact O-N 3.47Å; Y42-F46 VanDerWaalsContact O-CB 3.31Å; Y42-F46 WeakPolarHBondContact O-CB 3.5Å; Y42-F46 PolarHBondContact O-N 2.94Å; Y42-L88 HydrophobicContact CD1-CD1 4.33Å; Y42-L88 HydrophobicContact CD2-CD1 4.16Å; Y42-L88 HydrophobicContact CG-CD1 4.05Å; Y42-L88 HydrophobicContact CG-CG 4.21Å; Y42-L88 VanDerWaalsContact O-CD2 3.29Å; Y42-L88 WeakPolarHBondContact O-CD2 3.47Å; Y42-W91 HydrophobicContact CD2-CB 3.91Å; Y42-W91 HydrophobicContact CE2-CB 3.79Å; Y42-A92 HydrophobicContact CD2-CB 4.4Å; Y42-Y95 HydrophobicContact CD2-CD2 4.37Å; Y42-Y95 AromaticContact CE2-CD2 3.67Å; Y42-Y95 HydrophobicContact CE2-CD2 3.67Å; Y42-Y95 AromaticContact CE2-CE2 3.62Å; Y42-Y95 HydrophobicContact CE2-CE2 3.62Å; Y42-C297 HydrophobicContact CE1-CB 4.31Å; Y42-C297 WeakPolarHBondContact CE1-SG 3.48Å; Y42-F300 HydrophobicContact CD1-CD2 4.14Å; Y42-F300 AromaticContact CE1-CD2 3.48Å; Y42-F300 HydrophobicContact CE1-CD2 3.48Å; Y42-F300 VanDerWaalsContact CE1-CD2 3.48Å; Y42-F300 AromaticContact CE1-CE2 3.88Å; Y42-F300 HydrophobicContact CE1-CE2 3.88Å; Y42-F300 HydrophobicContact CE2-CE2 4.27Å; Y42-F300 AromaticContact CZ-CD2 3.74Å; Y42-F300 AromaticContact CZ-CE2 3.62Å; Y42-F300 WeakPolarHBondContact OH-CE2 3.27Å
43	S	96.9	Very high	93	Very high	62 Å²	62	52.8 Å²	52.8	43%	0.434	28%	0.283	S	S	.	.	H	α-helix	trans	-63.1	-41.6	174.4	-63.5	0	0	0	0	112	P39 T40 I41 F46 V47	P39-S43 PolarHBondContact O-N 3.42Å; P39-S43 PolarHBondContact O-OG 3.39Å; P39-S43 VanDerWaalsContact O-OG 3.07Å; T40-S43 PolarHBondContact O-N 3.35Å; I41-S43 VanDerWaalsContact C-N 3.35Å; I41-S43 PolarHBondContact O-N 2.86Å; S43-F46 PolarHBondContact O-N 3.39Å; S43-V47 WeakPolarHBondContact O-CG2 3.46Å; S43-V47 PolarHBondContact O-N 3.25Å
44	V	97.2	Very high	94.1	Very high	76 Å²	76	49.9 Å²	49.9	46%	0.461	27%	0.271	S	S	.	.	H	α-helix	trans	-64.7	-47.2	175.8	172.7	0	0	0	0	111.1	T40 I41 F46 V47 L48	T40-V44 WeakPolarHBondContact O-CG2 3.46Å; T40-V44 PolarHBondContact O-N 2.83Å; I41-V44 PolarHBondContact O-N 2.86Å; V44-F46 VanDerWaalsContact C-N 3.28Å; V44-F46 PolarHBondContact O-N 3.26Å; V44-V47 PolarHBondContact O-N 3.42Å; V44-L48 HydrophobicContact CG1-CD1 3.73Å; V44-L48 HydrophobicContact CG1-CG 4.24Å; V44-L48 WeakPolarHBondContact O-CB 3.28Å; V44-L48 WeakPolarHBondContact O-CG 3.25Å; V44-L48 PolarHBondContact O-N 3.29Å
45	I	97.6	Very high	94.6	Very high	6 Å²	6	52.6 Å²	52.6	3%	0.031	29%	0.286	C	S	.	.	H	α-helix	trans	-58.8	-43.1	176.4	-67.3	167.6	0	0	0	110.3	I41 Y42 G49 L85 L88 F300 S301 A304	I41-I45 HydrophobicContact CG2-CD1 3.66Å; I41-I45 HydrophobicContact CG2-CG1 4.27Å; I41-I45 VanDerWaalsContact O-CG1 3.28Å; I41-I45 WeakPolarHBondContact O-CG1 3.38Å; I41-I45 PolarHBondContact O-N 3.09Å; Y42-I45 HydrophobicContact CD1-CD1 4.46Å; Y42-I45 PolarHBondContact O-N 3.47Å; I45-G49 WeakPolarHBondContact O-CA 2.95Å; I45-G49 PolarHBondContact O-N 2.92Å; I45-L85 HydrophobicContact CG2-CD2 3.93Å; I45-L88 HydrophobicContact CB-CD2 3.78Å; I45-L88 HydrophobicContact CG2-CD2 3.49Å; I45-L88 VanDerWaalsContact CG2-CD2 3.49Å; I45-F300 HydrophobicContact CD1-CB 3.96Å; I45-F300 WeakPolarHBondContact CG2-O 3.23Å; I45-S301 WeakPolarHBondContact CD1-OG 3.28Å; I45-A304 HydrophobicContact CG2-CB 4.15Å
46	F	97.9	Very high	94.9	Very high	60 Å²	60	51.3 Å²	51.3	26%	0.263	28%	0.279	S	S	.	.	H	α-helix	trans	-58.9	-55	177	172.9	-107.3	0	0	0	111.2	Y42 S43 V44 F50 L85 L88 P89	Y42-F46 VanDerWaalsContact O-CB 3.31Å; Y42-F46 WeakPolarHBondContact O-CB 3.5Å; Y42-F46 PolarHBondContact O-N 2.94Å; S43-F46 PolarHBondContact O-N 3.39Å; V44-F46 VanDerWaalsContact C-N 3.28Å; V44-F46 PolarHBondContact O-N 3.26Å; F46-F50 HydrophobicContact CD2-CB 4.35Å; F46-F50 HydrophobicContact CE2-CB 4.2Å; F46-F50 HydrophobicContact CE2-CD2 4.05Å; F46-F50 HydrophobicContact CE2-CG 4.11Å; F46-F50 HydrophobicContact CZ-CG 4.38Å; F46-F50 WeakPolarHBondContact O-CA 3.24Å; F46-F50 WeakPolarHBondContact O-CB 3.42Å; F46-F50 PolarHBondContact O-N 2.99Å; F46-L85 HydrophobicContact CD2-CB 4.49Å; F46-L85 VanDerWaalsContact CD2-O 3.26Å; F46-L85 WeakPolarHBondContact CD2-O 3.28Å; F46-L88 HydrophobicContact CB-CD2 4.22Å; F46-P89 HydrophobicContact CD1-CG 4.41Å; F46-P89 HydrophobicContact CD2-CG 3.9Å; F46-P89 HydrophobicContact CE1-CG 4.42Å; F46-P89 HydrophobicContact CE2-CG 3.91Å; F46-P89 HydrophobicContact CG-CG 4.15Å; F46-P89 HydrophobicContact CZ-CG 4.18Å
47	V	97.3	Very high	95.1	Very high	82 Å²	82	45 Å²	45	50%	0.497	25%	0.254	S	S	.	.	H	α-helix	trans	-61.9	-52.5	-176.5	172.6	0	0	0	0	111.2	S43 V44 V51	S43-V47 WeakPolarHBondContact O-CG2 3.46Å; S43-V47 PolarHBondContact O-N 3.25Å; V44-V47 PolarHBondContact O-N 3.42Å; V47-V51 WeakPolarHBondContact O-CB 3.02Å; V47-V51 VanDerWaalsContact O-CG2 3.25Å; V47-V51 WeakPolarHBondContact O-CG2 3.43Å; V47-V51 PolarHBondContact O-N 3.31Å; V47-V51 VanDerWaalsContact O-N 3.16Å
48	L	95.9	Very high	95	Very high	81 Å²	81	46.4 Å²	46.4	42%	0.424	26%	0.257	S	S	.	.	H	α-helix	trans	-66.6	-45.9	-176.6	-63.5	-177.9	0	0	0	111.6	V44 G52 A304 F308	V44-L48 HydrophobicContact CG1-CD1 3.73Å; V44-L48 HydrophobicContact CG1-CG 4.24Å; V44-L48 WeakPolarHBondContact O-CB 3.28Å; V44-L48 WeakPolarHBondContact O-CG 3.25Å; V44-L48 PolarHBondContact O-N 3.29Å; L48-G52 PolarHBondContact O-N 2.89Å; L48-A304 HydrophobicContact CB-CB 4.39Å; L48-F308 HydrophobicContact CB-CE2 4.29Å; L48-F308 HydrophobicContact CB-CZ 4.39Å; L48-F308 HydrophobicContact CD1-CZ 4.46Å; L48-F308 HydrophobicContact CD2-CZ 4.36Å
49	G	96.4	Very high	94.6	Very high	0 Å²	0	46.4 Å²	46.4	0%	0	26%	0.257	C	S	.	.	H	α-helix	trans	-67.7	-43	-179.7	0	0	0	0	0	112.7	I45 N53	I45-G49 WeakPolarHBondContact O-CA 2.95Å; I45-G49 PolarHBondContact O-N 2.92Å; G49-N53 VanDerWaalsContact O-CB 3.28Å; G49-N53 WeakPolarHBondContact O-CB 3.35Å; G49-N53 PolarHBondContact O-N 2.8Å; G49-N53 PolarHBondContact O-ND2 3.35Å
50	F	96.6	Very high	94.2	Very high	63 Å²	63	46.1 Å²	46.1	28%	0.276	26%	0.255	S	S	.	.	H	α-helix	trans	-69.3	-48.1	-175.6	-169	-99.6	0	0	0	110.9	F46 I54 L82 L85 I86	F46-F50 HydrophobicContact CD2-CB 4.35Å; F46-F50 HydrophobicContact CE2-CB 4.2Å; F46-F50 HydrophobicContact CE2-CD2 4.05Å; F46-F50 HydrophobicContact CE2-CG 4.11Å; F46-F50 HydrophobicContact CZ-CG 4.38Å; F46-F50 WeakPolarHBondContact O-CA 3.24Å; F46-F50 WeakPolarHBondContact O-CB 3.42Å; F46-F50 PolarHBondContact O-N 2.99Å; F50-I54 HydrophobicContact CD1-CD1 3.6Å; F50-I54 HydrophobicContact CE1-CD1 3.22Å; F50-I54 HydrophobicContact CE1-CG1 4.46Å; F50-I54 HydrophobicContact CE2-CD1 4.3Å; F50-I54 HydrophobicContact CG-CD1 4.29Å; F50-I54 HydrophobicContact CZ-CD1 3.62Å; F50-I54 WeakPolarHBondContact O-CB 3.37Å; F50-I54 WeakPolarHBondContact O-CG1 3.41Å; F50-I54 PolarHBondContact O-N 2.85Å; F50-L82 HydrophobicContact CD2-CD2 3.7Å; F50-L82 HydrophobicContact CE2-CD2 4.04Å; F50-L82 HydrophobicContact CG-CD2 4.26Å; F50-L85 HydrophobicContact CD2-CB 4.38Å; F50-I86 HydrophobicContact CE2-CD1 4.45Å; F50-I86 HydrophobicContact CE2-CG1 3.88Å
51	V	95.5	Very high	93.7	Very high	96 Å²	96	45.1 Å²	45.1	58%	0.582	25%	0.25	S	S	*	.	H	α-helix	trans	-61.6	-47.4	176.1	175.1	0	0	0	0	110.5	V47 L55	V47-V51 WeakPolarHBondContact O-CB 3.02Å; V47-V51 VanDerWaalsContact O-CG2 3.25Å; V47-V51 WeakPolarHBondContact O-CG2 3.43Å; V47-V51 PolarHBondContact O-N 3.31Å; V47-V51 VanDerWaalsContact O-N 3.16Å; V51-L55 WeakPolarHBondContact O-CB 3.26Å; V51-L55 PolarHBondContact O-N 3.08Å
52	G	93.6	Very high	92.9	Very high	14 Å²	14	44.3 Å²	44.3	14%	0.144	25%	0.246	C	C	.	.	H	α-helix	trans	-61.2	-49.1	-179.2	0	0	0	0	0	112.8	L48 L55 V56 P307	L48-G52 PolarHBondContact O-N 2.89Å; G52-L55 WeakPolarHBondContact O-CB 3.36Å; G52-L55 PolarHBondContact O-N 3.49Å; G52-V56 VanDerWaalsContact O-CG2 3.28Å; G52-V56 WeakPolarHBondContact O-CG2 3.34Å; G52-V56 PolarHBondContact O-N 2.92Å; G52-P307 VanDerWaalsContact C-CG 3.41Å
53	N	95.4	Very high	91.6	Very high	0 Å²	0	54.5 Å²	54.5	0%	0	29%	0.29	C	S	.	.	H	α-helix	trans	-72.1	-33.3	-177.2	-73.6	-67.6	0	0	0	112.6	G49 L55 V56 V57 A78 L82 S303 P307	G49-N53 VanDerWaalsContact O-CB 3.28Å; G49-N53 WeakPolarHBondContact O-CB 3.35Å; G49-N53 PolarHBondContact O-N 2.8Å; G49-N53 PolarHBondContact O-ND2 3.35Å; N53-L55 VanDerWaalsContact C-N 3.33Å; N53-L55 PolarHBondContact O-N 3.38Å; N53-V56 PolarHBondContact O-N 3.17Å; N53-V57 WeakPolarHBondContact O-CG2 3.38Å; N53-V57 PolarHBondContact O-N 3.46Å; N53-A78 HydrophobicContact CB-CB 4.21Å; N53-L82 HydrophobicContact CB-CD1 4.26Å; N53-L82 HydrophobicContact CB-CD2 3.75Å; N53-L82 HydrophobicContact CB-CG 3.7Å; N53-S303 PolarHBondContact ND2-O 3.45Å; N53-P307 HydrophobicContact CB-CG 4.34Å; N53-P307 WeakPolarHBondContact OD1-CG 3.45Å
54	I	95.2	Very high	90.2	Very high	78 Å²	78	55.7 Å²	55.7	40%	0.4	30%	0.298	S	S	.	.	H	α-helix	trans	-60.2	-45.7	169.7	-76.7	173.1	0	0	0	110.4	F50 V56 V57 F58 L82	F50-I54 HydrophobicContact CD1-CD1 3.6Å; F50-I54 HydrophobicContact CE1-CD1 3.22Å; F50-I54 HydrophobicContact CE1-CG1 4.46Å; F50-I54 HydrophobicContact CE2-CD1 4.3Å; F50-I54 HydrophobicContact CG-CD1 4.29Å; F50-I54 HydrophobicContact CZ-CD1 3.62Å; F50-I54 WeakPolarHBondContact O-CB 3.37Å; F50-I54 WeakPolarHBondContact O-CG1 3.41Å; F50-I54 PolarHBondContact O-N 2.85Å; I54-V56 VanDerWaalsContact C-N 3.3Å; I54-V56 PolarHBondContact O-N 3.44Å; I54-V57 PolarHBondContact O-N 2.94Å; I54-F58 VanDerWaalsContact O-CB 3.28Å; I54-F58 WeakPolarHBondContact O-CB 3.24Å; I54-F58 PolarHBondContact O-N 2.95Å; I54-L82 HydrophobicContact CD1-CD2 4.49Å; I54-L82 HydrophobicContact CG1-CD1 4.15Å; I54-L82 HydrophobicContact CG1-CD2 3.77Å
55	L	91.6	Very high	88.8	Confident	67 Å²	67	53 Å²	53	35%	0.351	28%	0.281	S	S	.	.	H	α-helix	trans	-61	-42	178.7	-174.8	63.9	0	0	0	111.1	V51 G52 N53 F58 V59 F317 L321	V51-L55 WeakPolarHBondContact O-CB 3.26Å; V51-L55 PolarHBondContact O-N 3.08Å; G52-L55 WeakPolarHBondContact O-CB 3.36Å; G52-L55 PolarHBondContact O-N 3.49Å; N53-L55 VanDerWaalsContact C-N 3.33Å; N53-L55 PolarHBondContact O-N 3.38Å; L55-F58 PolarHBondContact O-N 2.78Å; L55-V59 HydrophobicContact CD1-CG2 4.18Å; L55-V59 HydrophobicContact CG-CG2 4.42Å; L55-V59 WeakPolarHBondContact O-CB 3.26Å; L55-V59 VanDerWaalsContact O-CG2 3.29Å; L55-V59 WeakPolarHBondContact O-CG2 3.44Å; L55-V59 PolarHBondContact O-N 2.8Å; L55-F317 HydrophobicContact CD2-CE1 4.31Å; L55-F317 HydrophobicContact CG-CE1 4.34Å; L55-F317 HydrophobicContact CG-CZ 4.1Å; L55-L321 HydrophobicContact CD1-CD2 4.11Å
56	V	90.6	Very high	87.5	Confident	1 Å²	1	62.9 Å²	62.9	1%	0.006	32%	0.318	C	S	.	.	H	α-helix	trans	-58.3	-51.7	176	170.9	0	0	0	0	111.2	G52 N53 I54 F58 V59 L60 I74 A78 P307 Y310 F317	G52-V56 VanDerWaalsContact O-CG2 3.28Å; G52-V56 WeakPolarHBondContact O-CG2 3.34Å; G52-V56 PolarHBondContact O-N 2.92Å; N53-V56 PolarHBondContact O-N 3.17Å; I54-V56 VanDerWaalsContact C-N 3.3Å; I54-V56 PolarHBondContact O-N 3.44Å; V56-F58 PolarHBondContact O-N 2.72Å; V56-V59 PolarHBondContact O-N 3.4Å; V56-L60 HydrophobicContact CG1-CD1 3.86Å; V56-L60 WeakPolarHBondContact O-CB 3.42Å; V56-L60 WeakPolarHBondContact O-CG 3.39Å; V56-L60 PolarHBondContact O-N 3.34Å; V56-I74 HydrophobicContact CG1-CG2 3.79Å; V56-A78 HydrophobicContact CB-CB 4.31Å; V56-A78 HydrophobicContact CG1-CB 3.91Å; V56-P307 HydrophobicContact CG2-CB 4.04Å; V56-P307 HydrophobicContact CG2-CG 4.36Å; V56-Y310 HydrophobicContact CG1-CD2 4.05Å; V56-Y310 HydrophobicContact CG1-CE2 4.37Å; V56-Y310 HydrophobicContact CG2-CD2 3.76Å; V56-F317 HydrophobicContact CB-CE2 4.49Å; V56-F317 HydrophobicContact CG2-CE2 4.32Å; V56-F317 HydrophobicContact CG2-CZ 4.17Å
57	V	91.8	Very high	86.6	Confident	31 Å²	31	64.3 Å²	64.3	19%	0.188	32%	0.324	C	S	.	.	H	α-helix	trans	-60.4	-47.7	177.6	173.8	0	0	0	0	110.4	N53 I54 V59 L60 C61 A78 L79 L82	N53-V57 WeakPolarHBondContact O-CG2 3.38Å; N53-V57 PolarHBondContact O-N 3.46Å; I54-V57 PolarHBondContact O-N 2.94Å; V57-V59 PolarHBondContact O-N 2.99Å; V57-L60 PolarHBondContact O-N 2.89Å; V57-C61 WeakPolarHBondContact O-CB 3.14Å; V57-C61 PolarHBondContact O-N 3.18Å; V57-C61 PolarHBondContact O-SG 3.33Å; V57-A78 HydrophobicContact CG2-CB 3.74Å; V57-L79 HydrophobicContact CG2-CD2 4.34Å; V57-L79 HydrophobicContact CG2-CG 4.46Å; V57-L82 HydrophobicContact CG2-CD1 4.15Å
58	F	89.1	Confident	85.9	Confident	110 Å²	110	62.8 Å²	62.8	48%	0.482	32%	0.315	S	S	.	.	H	α-helix	trans	-57.7	-49.7	-179.3	174.8	-103.2	0	0	0	112.3	I54 L55 V56 Q62	I54-F58 VanDerWaalsContact O-CB 3.28Å; I54-F58 WeakPolarHBondContact O-CB 3.24Å; I54-F58 PolarHBondContact O-N 2.95Å; L55-F58 PolarHBondContact O-N 2.78Å; V56-F58 PolarHBondContact O-N 2.72Å; F58-Q62 WeakPolarHBondContact O-CG 3.43Å; F58-Q62 PolarHBondContact O-N 2.98Å
59	V	85.6	Confident	85.5	Confident	0 Å²	0	59.4 Å²	59.4	0%	0	30%	0.298	C	S	.	.	H	α-helix	trans	-64.9	-53.1	-179.6	170.8	0	0	0	0	110.4	L55 V56 V57 C61 Q62 N65 F317 Q320 L321 L324	L55-V59 HydrophobicContact CD1-CG2 4.18Å; L55-V59 HydrophobicContact CG-CG2 4.42Å; L55-V59 WeakPolarHBondContact O-CB 3.26Å; L55-V59 VanDerWaalsContact O-CG2 3.29Å; L55-V59 WeakPolarHBondContact O-CG2 3.44Å; L55-V59 PolarHBondContact O-N 2.8Å; V56-V59 PolarHBondContact O-N 3.4Å; V57-V59 PolarHBondContact O-N 2.99Å; V59-C61 VanDerWaalsContact C-N 3.3Å; V59-C61 PolarHBondContact O-N 2.86Å; V59-Q62 PolarHBondContact O-N 3.33Å; V59-N65 PolarHBondContact O-ND2 3.44Å; V59-F317 HydrophobicContact CB-CD2 4.26Å; V59-F317 HydrophobicContact CB-CE2 3.41Å; V59-F317 VanDerWaalsContact CB-CE2 3.41Å; V59-F317 HydrophobicContact CB-CZ 3.74Å; V59-F317 HydrophobicContact CG1-CD2 3.83Å; V59-F317 HydrophobicContact CG1-CE2 3.49Å; V59-F317 VanDerWaalsContact CG1-CE2 3.49Å; V59-F317 HydrophobicContact CG1-CZ 4.09Å; V59-F317 HydrophobicContact CG2-CE1 4.44Å; V59-F317 HydrophobicContact CG2-CE2 3.88Å; V59-F317 HydrophobicContact CG2-CZ 3.64Å; V59-Q320 HydrophobicContact CG1-CB 4.02Å; V59-L321 HydrophobicContact CG2-CD2 3.34Å; V59-L321 HydrophobicContact CG2-CG 3.84Å; V59-L324 HydrophobicContact CB-CD1 4.4Å; V59-L324 HydrophobicContact CG1-CD1 3.95Å; V59-L324 HydrophobicContact CG2-CD1 4.24Å
60	L	84.8	Confident	84.9	Confident	8 Å²	8	59.8 Å²	59.8	4%	0.042	30%	0.301	C	S	.	.	H	α-helix	trans	-70.6	-25.1	-173.8	-64.2	-179.5	0	0	0	113.4	V56 V57 K67 I74 V75 F317	V56-L60 HydrophobicContact CG1-CD1 3.86Å; V56-L60 WeakPolarHBondContact O-CB 3.42Å; V56-L60 WeakPolarHBondContact O-CG 3.39Å; V56-L60 PolarHBondContact O-N 3.34Å; V57-L60 PolarHBondContact O-N 2.89Å; L60-K67 PolarHBondContact O-NZ 2.88Å; L60-I74 HydrophobicContact CD1-CB 3.98Å; L60-I74 HydrophobicContact CD1-CG2 3.48Å; L60-I74 VanDerWaalsContact CD1-CG2 3.48Å; L60-V75 HydrophobicContact CB-CG2 3.63Å; L60-V75 HydrophobicContact CD1-CG2 3.97Å; L60-V75 HydrophobicContact CG-CG2 4.47Å; L60-F317 HydrophobicContact CD2-CD2 4.45Å; L60-F317 HydrophobicContact CG-CE2 4.46Å
61	C	85.6	Confident	84.4	Confident	63 Å²	63	57.5 Å²	57.5	43%	0.426	29%	0.291	S	S	.	.	H	α-helix	trans	-80.3	-15.5	178.5	-73.3	0	0	0	0	113.9	V57 V59 K67	V57-C61 WeakPolarHBondContact O-CB 3.14Å; V57-C61 PolarHBondContact O-N 3.18Å; V57-C61 PolarHBondContact O-SG 3.33Å; V59-C61 VanDerWaalsContact C-N 3.3Å; V59-C61 PolarHBondContact O-N 2.86Å; C61-K67 VanDerWaalsContact C-NZ 3.29Å; C61-K67 VanDerWaalsContact CA-NZ 3.34Å; C61-K67 PolarHBondContact O-NZ 2.84Å
62	Q	79.1	Confident	84.1	Confident	31 Å²	31	54 Å²	54	15%	0.145	27%	0.271	C	S	.	.	S	Bend	trans	-57.9	144	-179.6	-82.8	-178.8	105.6	0	0	113.6	F58 V59 S64 N65 L324	F58-Q62 WeakPolarHBondContact O-CG 3.43Å; F58-Q62 PolarHBondContact O-N 2.98Å; V59-Q62 PolarHBondContact O-N 3.33Å; Q62-S64 VanDerWaalsContact C-N 3.26Å; Q62-S64 PolarHBondContact O-N 3.29Å; Q62-N65 PolarHBondContact O-N 2.94Å; Q62-N65 VanDerWaalsContact O-N 3.12Å; Q62-L324 HydrophobicContact CB-CD2 4.49Å; Q62-L324 VanDerWaalsContact OE1-CD2 3.3Å
63	K	69.3	Low	84.1	Confident	216 Å²	216	54 Å²	54	94%	0.939	27%	0.266	S	S	*	.	T	Hydrogen-bonded Turn	trans	-61.9	-33.2	-176.5	-67.2	-175.4	179.9	-178.6	0	112.9	N65	K63-N65 PolarHBondContact O-N 2.83Å
64	S	67.1	Low	83.9	Confident	86 Å²	86	54.3 Å²	54.3	60%	0.601	27%	0.268	S	S	*	.	T	Hydrogen-bonded Turn	trans	-67.9	-21.6	178.2	-174	0	0	0	0	112.9	Q62	Q62-S64 VanDerWaalsContact C-N 3.26Å; Q62-S64 PolarHBondContact O-N 3.29Å
65	N	69	Low	83.8	Confident	19 Å²	19	51.7 Å²	51.7	10%	0.102	26%	0.255	C	S	.	.	S	Bend	trans	-85.5	134.8	-176.7	-85.8	-22.7	0	0	0	112.8	V59 Q62 K63 K67 Q320	V59-N65 PolarHBondContact O-ND2 3.44Å; Q62-N65 PolarHBondContact O-N 2.94Å; Q62-N65 VanDerWaalsContact O-N 3.12Å; K63-N65 PolarHBondContact O-N 2.83Å; N65-K67 PolarHBondContact O-N 2.82Å; N65-Q320 PolarHBondContact ND2-OE1 3.42Å; N65-Q320 WeakPolarHBondContact OD1-CG 3.46Å
66	R	70.6	Confident	84	Confident	214 Å²	214	49.6 Å²	49.6	81%	0.808	25%	0.245	S	C	*	.	P	Polyproline II helix	trans	-61.6	126.9	175.5	-70.1	-171.3	179.1	-173.9	0.1	110.3	T68 N71	R66-T68 PolarHBondContact O-N 2.8Å; R66-N71 PolarHBondContact O-ND2 3.21Å
67	K	78.5	Confident	84.3	Confident	91 Å²	91	49.6 Å²	49.6	40%	0.396	24%	0.244	S	C	.	.	P	Polyproline II helix	trans	-81.5	118	174	-56.7	-59.6	176	-178.2	0	108.8	L60 C61 N65 L149	L60-K67 PolarHBondContact O-NZ 2.88Å; C61-K67 VanDerWaalsContact C-NZ 3.29Å; C61-K67 VanDerWaalsContact CA-NZ 3.34Å; C61-K67 PolarHBondContact O-NZ 2.84Å; N65-K67 PolarHBondContact O-N 2.82Å; K67-L149 HydrophobicContact CB-CD1 3.81Å; K67-L149 HydrophobicContact CB-CD2 4.27Å
68	T	83.6	Confident	84.5	Confident	50 Å²	50	48.1 Å²	48.1	31%	0.307	24%	0.235	S	C	.	.			trans	-122.1	160.5	176.9	71.2	0	0	0	0	109.7	R66 A70 N71 T72	R66-T68 PolarHBondContact O-N 2.8Å; T68-A70 VanDerWaalsContact C-N 3.26Å; T68-A70 PolarHBondContact O-N 3.36Å; T68-N71 PolarHBondContact O-N 3.41Å; T68-N71 WeakPolarHBondContact OG1-CB 3.5Å; T68-N71 PolarHBondContact OG1-N 2.94Å; T68-N71 PolarHBondContact OG1-ND2 2.72Å; T68-N71 PolarHBondContact OG1-OD1 3.5Å; T68-T72 PolarHBondContact O-N 3.3Å; T68-T72 PolarHBondContact O-OG1 2.89Å
69	V	86.1	Confident	84.8	Confident	9 Å²	9	46.3 Å²	46.3	6%	0.055	23%	0.23	C	C	.	.	H	α-helix	trans	-56.1	-44.4	174.1	175.7	0	0	0	0	110.6	T72 Y73 D132 R147 A152	V69-T72 WeakPolarHBondContact O-CB 3.31Å; V69-T72 PolarHBondContact O-N 3.12Å; V69-Y73 HydrophobicContact CG1-CD2 4.05Å; V69-Y73 HydrophobicContact CG1-CE2 3.41Å; V69-Y73 VanDerWaalsContact CG1-CE2 3.41Å; V69-Y73 PolarHBondContact O-N 3.33Å; V69-Y73 VanDerWaalsContact O-N 3.14Å; V69-D132 WeakPolarHBondContact CG1-OD1 3.42Å; V69-R147 HydrophobicContact CG2-CB 4.1Å; V69-A152 HydrophobicContact CB-CB 4.35Å; V69-A152 HydrophobicContact CG1-CB 3.92Å; V69-A152 HydrophobicContact CG2-CB 4.18Å
70	A	83.7	Confident	85.4	Confident	8 Å²	8	46.3 Å²	46.3	7%	0.066	23%	0.231	C	C	.	.	H	α-helix	trans	-60.3	-47.8	176	0	0	0	0	0	112.4	T68 T72 Y73 I74	T68-A70 VanDerWaalsContact C-N 3.26Å; T68-A70 PolarHBondContact O-N 3.36Å; A70-T72 PolarHBondContact O-N 3.37Å; A70-Y73 PolarHBondContact O-N 3.32Å; A70-I74 VanDerWaalsContact O-CG1 3.29Å; A70-I74 WeakPolarHBondContact O-CG1 3.29Å; A70-I74 PolarHBondContact O-N 3.43Å
71	N	86.1	Confident	86	Confident	15 Å²	15	46 Å²	46	8%	0.08	23%	0.229	C	C	.	.	H	α-helix	trans	-62	-32.4	177.9	-67	-4.2	0	0	0	111.7	R66 T68 V75	R66-N71 PolarHBondContact O-ND2 3.21Å; T68-N71 PolarHBondContact O-N 3.41Å; T68-N71 WeakPolarHBondContact OG1-CB 3.5Å; T68-N71 PolarHBondContact OG1-N 2.94Å; T68-N71 PolarHBondContact OG1-ND2 2.72Å; T68-N71 PolarHBondContact OG1-OD1 3.5Å; N71-V75 WeakPolarHBondContact O-CB 3.32Å; N71-V75 VanDerWaalsContact O-CG2 3.27Å; N71-V75 WeakPolarHBondContact O-CG2 3.45Å; N71-V75 PolarHBondContact O-N 3.11Å
72	T	90.6	Very high	86.6	Confident	24 Å²	24	44 Å²	44	15%	0.147	21%	0.214	C	C	.	.	H	α-helix	trans	-65	-46.3	176.5	-56	0	0	0	0	110.7	T68 V69 A70 V75 N76 A152	T68-T72 PolarHBondContact O-N 3.3Å; T68-T72 PolarHBondContact O-OG1 2.89Å; V69-T72 WeakPolarHBondContact O-CB 3.31Å; V69-T72 PolarHBondContact O-N 3.12Å; A70-T72 PolarHBondContact O-N 3.37Å; T72-V75 PolarHBondContact O-N 3.2Å; T72-N76 PolarHBondContact O-N 2.67Å; T72-N76 VanDerWaalsContact O-N 3.15Å; T72-N76 PolarHBondContact O-ND2 3.33Å; T72-A152 HydrophobicContact CG2-CB 4.24Å
73	Y	92.6	Very high	87.5	Confident	12 Å²	12	45.9 Å²	45.9	5%	0.047	23%	0.225	C	C	.	.	H	α-helix	trans	-68.5	-38.7	177.5	-61.1	-35.9	0	0	0	112.7	V69 A70 V75 N76 L77 F125 C128 M129 D132 A152 I155	V69-Y73 HydrophobicContact CG1-CD2 4.05Å; V69-Y73 HydrophobicContact CG1-CE2 3.41Å; V69-Y73 VanDerWaalsContact CG1-CE2 3.41Å; V69-Y73 PolarHBondContact O-N 3.33Å; V69-Y73 VanDerWaalsContact O-N 3.14Å; A70-Y73 PolarHBondContact O-N 3.32Å; Y73-V75 PolarHBondContact O-N 3.47Å; Y73-N76 PolarHBondContact O-N 3.5Å; Y73-L77 WeakPolarHBondContact O-CB 3.43Å; Y73-L77 PolarHBondContact O-N 3.49Å; Y73-F125 AromaticContact CD1-CD1 3.91Å; Y73-F125 HydrophobicContact CD1-CD1 3.91Å; Y73-F125 HydrophobicContact CD1-CE1 4.15Å; Y73-F125 HydrophobicContact CG-CD1 4.44Å; Y73-C128 HydrophobicContact CD2-CB 4.47Å; Y73-C128 HydrophobicContact CE2-CB 4.14Å; Y73-M129 HydrophobicContact CD2-CG 3.98Å; Y73-M129 HydrophobicContact CG-CG 4.23Å; Y73-D132 HydrophobicContact CE2-CB 4.35Å; Y73-A152 HydrophobicContact CE1-CB 4.29Å; Y73-I155 HydrophobicContact CE1-CG2 4.15Å
74	I	91.6	Very high	88.9	Confident	8 Å²	8	35.6 Å²	35.6	4%	0.041	18%	0.18	C	C	.	.	H	α-helix	trans	-61.7	-43.1	175.7	-64.9	165.1	0	0	0	111.1	V56 L60 A70 L77 A78 M129 M249 Y310	V56-I74 HydrophobicContact CG1-CG2 3.79Å; L60-I74 HydrophobicContact CD1-CB 3.98Å; L60-I74 HydrophobicContact CD1-CG2 3.48Å; L60-I74 VanDerWaalsContact CD1-CG2 3.48Å; A70-I74 VanDerWaalsContact O-CG1 3.29Å; A70-I74 WeakPolarHBondContact O-CG1 3.29Å; A70-I74 PolarHBondContact O-N 3.43Å; I74-L77 PolarHBondContact O-N 3.05Å; I74-A78 WeakPolarHBondContact O-CB 3.46Å; I74-A78 PolarHBondContact O-N 3.49Å; I74-M129 HydrophobicContact CG1-SD 4.02Å; I74-M249 HydrophobicContact CD1-CE 3.78Å; I74-M249 HydrophobicContact CD1-SD 4.24Å; I74-M249 HydrophobicContact CG1-CE 4.49Å; I74-Y310 HydrophobicContact CG1-CE1 4.32Å; I74-Y310 HydrophobicContact CG2-CD1 4.35Å; I74-Y310 HydrophobicContact CG2-CD2 3.97Å; I74-Y310 HydrophobicContact CG2-CE1 4.17Å; I74-Y310 HydrophobicContact CG2-CE2 3.78Å; I74-Y310 HydrophobicContact CG2-CG 4.28Å
75	V	93.3	Very high	90.4	Very high	22 Å²	22	31.5 Å²	31.5	13%	0.133	15%	0.151	C	C	.	.	H	α-helix	trans	-63.1	-43.2	176.8	168.3	0	0	0	0	111.2	L60 N71 T72 Y73 L77 A78 L79	L60-V75 HydrophobicContact CB-CG2 3.63Å; L60-V75 HydrophobicContact CD1-CG2 3.97Å; L60-V75 HydrophobicContact CG-CG2 4.47Å; N71-V75 WeakPolarHBondContact O-CB 3.32Å; N71-V75 VanDerWaalsContact O-CG2 3.27Å; N71-V75 WeakPolarHBondContact O-CG2 3.45Å; N71-V75 PolarHBondContact O-N 3.11Å; T72-V75 PolarHBondContact O-N 3.2Å; Y73-V75 PolarHBondContact O-N 3.47Å; V75-L77 VanDerWaalsContact C-N 3.34Å; V75-L77 PolarHBondContact O-N 2.91Å; V75-A78 PolarHBondContact O-N 3.32Å; V75-L79 HydrophobicContact CG1-CD1 4.11Å; V75-L79 HydrophobicContact CG1-CG 4.44Å; V75-L79 VanDerWaalsContact O-CG 3.29Å; V75-L79 WeakPolarHBondContact O-CG 3.36Å; V75-L79 PolarHBondContact O-N 3.36Å
76	N	96.4	Very high	91.7	Very high	24 Å²	24	34.8 Å²	34.8	13%	0.128	17%	0.168	C	C	.	.	H	α-helix	trans	-66.2	-37	178.2	-78.4	-88.9	0	0	0	112.5	T72 Y73 L79 S80 F125 S156 W160	T72-N76 PolarHBondContact O-N 2.67Å; T72-N76 VanDerWaalsContact O-N 3.15Å; T72-N76 PolarHBondContact O-ND2 3.33Å; Y73-N76 PolarHBondContact O-N 3.5Å; N76-L79 WeakPolarHBondContact O-CB 3.25Å; N76-L79 PolarHBondContact O-N 2.85Å; N76-S80 PolarHBondContact O-N 3.31Å; N76-S80 PolarHBondContact O-OG 2.83Å; N76-F125 HydrophobicContact CB-CD1 3.99Å; N76-F125 HydrophobicContact CB-CD2 4.08Å; N76-F125 HydrophobicContact CB-CE1 3.46Å; N76-F125 VanDerWaalsContact CB-CE1 3.46Å; N76-F125 HydrophobicContact CB-CE2 3.58Å; N76-F125 HydrophobicContact CB-CG 4.31Å; N76-F125 HydrophobicContact CB-CZ 3.27Å; N76-S156 PolarHBondContact ND2-OG 3.32Å; N76-W160 PolarHBondContact OD1-NE1 3.42Å
77	L	94.9	Very high	93	Very high	0 Å²	0	24.6 Å²	24.6	0%	0	13%	0.13	C	C	.	.	H	α-helix	trans	-63.9	-43.6	174.1	-176.8	55.8	0	0	0	111.5	Y73 I74 V75 L79 S80 D81 S122 F125 I126 M129 Y310	Y73-L77 WeakPolarHBondContact O-CB 3.43Å; Y73-L77 PolarHBondContact O-N 3.49Å; I74-L77 PolarHBondContact O-N 3.05Å; V75-L77 VanDerWaalsContact C-N 3.34Å; V75-L77 PolarHBondContact O-N 2.91Å; L77-L79 VanDerWaalsContact C-N 3.3Å; L77-L79 PolarHBondContact O-N 3.44Å; L77-S80 PolarHBondContact O-N 2.99Å; L77-S80 PolarHBondContact O-OG 3.02Å; L77-D81 WeakPolarHBondContact O-CB 3.46Å; L77-D81 PolarHBondContact O-N 3.3Å; L77-S122 VanDerWaalsContact CD1-CA 3.45Å; L77-S122 WeakPolarHBondContact CD1-OG 3.26Å; L77-F125 HydrophobicContact CB-CB 4.36Å; L77-I126 HydrophobicContact CD2-CG1 4.01Å; L77-M129 HydrophobicContact CD2-CE 3.6Å; L77-Y310 WeakPolarHBondContact CD2-OH 3.46Å
78	A	96	Very high	93.8	Very high	0 Å²	0	20.3 Å²	20.3	0%	0	11%	0.111	C	C	.	.	H	α-helix	trans	-63.5	-35.7	173.5	0	0	0	0	0	112.2	N53 V56 V57 I74 V75 D81 L82	N53-A78 HydrophobicContact CB-CB 4.21Å; V56-A78 HydrophobicContact CB-CB 4.31Å; V56-A78 HydrophobicContact CG1-CB 3.91Å; V57-A78 HydrophobicContact CG2-CB 3.74Å; I74-A78 WeakPolarHBondContact O-CB 3.46Å; I74-A78 PolarHBondContact O-N 3.49Å; V75-A78 PolarHBondContact O-N 3.32Å; A78-D81 PolarHBondContact O-N 2.89Å; A78-L82 WeakPolarHBondContact O-CB 3.19Å; A78-L82 VanDerWaalsContact O-CG 3.24Å; A78-L82 WeakPolarHBondContact O-CG 3.34Å; A78-L82 PolarHBondContact O-N 3.48Å
79	L	97.4	Very high	94.4	Very high	72 Å²	72	20.1 Å²	20.1	38%	0.377	11%	0.11	S	C	.	.	H	α-helix	trans	-66.9	-43.5	174.5	-72.2	171.8	0	0	0	112.1	V57 V75 N76 L77 D81 L82 L83 W160	V57-L79 HydrophobicContact CG2-CD2 4.34Å; V57-L79 HydrophobicContact CG2-CG 4.46Å; V75-L79 HydrophobicContact CG1-CD1 4.11Å; V75-L79 HydrophobicContact CG1-CG 4.44Å; V75-L79 VanDerWaalsContact O-CG 3.29Å; V75-L79 WeakPolarHBondContact O-CG 3.36Å; V75-L79 PolarHBondContact O-N 3.36Å; N76-L79 WeakPolarHBondContact O-CB 3.25Å; N76-L79 PolarHBondContact O-N 2.85Å; L77-L79 VanDerWaalsContact C-N 3.3Å; L77-L79 PolarHBondContact O-N 3.44Å; L79-D81 VanDerWaalsContact C-N 3.29Å; L79-D81 PolarHBondContact O-N 3.48Å; L79-L82 PolarHBondContact O-N 3.02Å; L79-L83 VanDerWaalsContact O-CG 3.31Å; L79-L83 WeakPolarHBondContact O-CG 3.34Å; L79-L83 PolarHBondContact O-N 3.1Å; L79-W160 HydrophobicContact CB-CZ2 4.41Å
80	S	97.8	Very high	95	Very high	1 Å²	1	22.6 Å²	22.6	1%	0.007	12%	0.121	C	C	.	.	H	α-helix	trans	-63.5	-37.1	175.1	57.9	0	0	0	0	111.9	N76 L77 F84 N118 S122	N76-S80 PolarHBondContact O-N 3.31Å; N76-S80 PolarHBondContact O-OG 2.83Å; L77-S80 PolarHBondContact O-N 2.99Å; L77-S80 PolarHBondContact O-OG 3.02Å; S80-F84 PolarHBondContact O-N 3.12Å; S80-N118 PolarHBondContact O-ND2 3.35Å; S80-S122 PolarHBondContact OG-OG 3.11Å
81	D	97.7	Very high	95.5	Very high	0 Å²	0	23.1 Å²	23.1	0%	0	12%	0.121	C	C	.	.	H	α-helix	trans	-64.4	-47.4	174.3	-74.3	-24.5	0	0	0	111.5	L77 A78 L79 L83 F84 L85 N118 S303 N306	L77-D81 WeakPolarHBondContact O-CB 3.46Å; L77-D81 PolarHBondContact O-N 3.3Å; A78-D81 PolarHBondContact O-N 2.89Å; L79-D81 VanDerWaalsContact C-N 3.29Å; L79-D81 PolarHBondContact O-N 3.48Å; D81-L83 PolarHBondContact O-N 2.98Å; D81-F84 PolarHBondContact O-N 3.42Å; D81-L85 HydrophobicContact CB-CD1 4.42Å; D81-L85 WeakPolarHBondContact O-CB 3.34Å; D81-L85 WeakPolarHBondContact O-CD1 3.43Å; D81-L85 WeakPolarHBondContact O-CG 3.28Å; D81-L85 PolarHBondContact O-N 3.2Å; D81-N118 WeakPolarHBondContact CA-ND2 3.45Å; D81-N118 PolarHBondContact N-ND2 2.84Å; D81-N118 PolarHBondContact OD1-ND2 2.85Å; D81-S303 VanDerWaalsContact OD1-CB 3.3Å; D81-S303 WeakPolarHBondContact OD1-CB 2.86Å; D81-S303 PolarHBondContact OD1-OG 3.21Å; D81-N306 PolarHBondContact OD2-ND2 3.21Å
82	L	98.3	Very high	96	Very high	21 Å²	21	22.8 Å²	22.8	11%	0.11	12%	0.12	C	C	.	.	H	α-helix	trans	-60.4	-43	177.8	-72.8	169.3	0	0	0	112.9	F50 N53 I54 V57 A78 L79 F84 L85 I86	F50-L82 HydrophobicContact CD2-CD2 3.7Å; F50-L82 HydrophobicContact CE2-CD2 4.04Å; F50-L82 HydrophobicContact CG-CD2 4.26Å; N53-L82 HydrophobicContact CB-CD1 4.26Å; N53-L82 HydrophobicContact CB-CD2 3.75Å; N53-L82 HydrophobicContact CB-CG 3.7Å; I54-L82 HydrophobicContact CD1-CD2 4.49Å; I54-L82 HydrophobicContact CG1-CD1 4.15Å; I54-L82 HydrophobicContact CG1-CD2 3.77Å; V57-L82 HydrophobicContact CG2-CD1 4.15Å; A78-L82 WeakPolarHBondContact O-CB 3.19Å; A78-L82 VanDerWaalsContact O-CG 3.24Å; A78-L82 WeakPolarHBondContact O-CG 3.34Å; A78-L82 PolarHBondContact O-N 3.48Å; L79-L82 PolarHBondContact O-N 3.02Å; L82-F84 VanDerWaalsContact C-N 3.3Å; L82-F84 PolarHBondContact O-N 2.98Å; L82-L85 PolarHBondContact O-N 3.38Å; L82-I86 WeakPolarHBondContact O-CG1 3.42Å; L82-I86 PolarHBondContact O-N 3.01Å; L82-I86 VanDerWaalsContact O-N 3.11Å
83	L	97.7	Very high	96.2	Very high	71 Å²	71	24.5 Å²	24.5	37%	0.372	13%	0.128	S	C	.	.	H	α-helix	trans	-58.6	-43	176.8	-74.8	175.6	0	0	0	111.7	L79 D81 L114 W160	L79-L83 VanDerWaalsContact O-CG 3.31Å; L79-L83 WeakPolarHBondContact O-CG 3.34Å; L79-L83 PolarHBondContact O-N 3.1Å; D81-L83 PolarHBondContact O-N 2.98Å; L83-L114 HydrophobicContact CB-CD2 4.09Å; L83-W160 HydrophobicContact CD1-CH2 3.93Å; L83-W160 HydrophobicContact CD1-CZ3 4.17Å
84	F	97.8	Very high	96.3	Very high	1 Å²	1	24.8 Å²	24.8	0%	0.004	13%	0.129	C	C	.	.	H	α-helix	trans	-68.9	-45	174.8	155.1	-109.9	0	0	0	112.6	S80 D81 L82 I86 S87 L88 L115 N118 F300	S80-F84 PolarHBondContact O-N 3.12Å; D81-F84 PolarHBondContact O-N 3.42Å; L82-F84 VanDerWaalsContact C-N 3.3Å; L82-F84 PolarHBondContact O-N 2.98Å; F84-I86 PolarHBondContact O-N 3.31Å; F84-S87 WeakPolarHBondContact O-CA 3.28Å; F84-S87 WeakPolarHBondContact O-CB 3.46Å; F84-S87 PolarHBondContact O-N 3.5Å; F84-S87 PolarHBondContact O-OG 3.28Å; F84-L88 HydrophobicContact CE2-CD1 3.95Å; F84-L88 HydrophobicContact CZ-CD1 3.63Å; F84-L88 HydrophobicContact CZ-CD2 4.48Å; F84-L115 HydrophobicContact CD2-CB 4.25Å; F84-L115 HydrophobicContact CD2-CD1 4.01Å; F84-L115 HydrophobicContact CE2-CD1 3.79Å; F84-N118 HydrophobicContact CB-CB 3.5Å; F84-N118 HydrophobicContact CG-CB 4.14Å; F84-F300 HydrophobicContact CE1-CB 4.18Å; F84-F300 HydrophobicContact CE1-CD1 4.47Å; F84-F300 HydrophobicContact CE1-CG 4.29Å; F84-F300 HydrophobicContact CE2-CD1 4.11Å; F84-F300 HydrophobicContact CE2-CD2 4.31Å; F84-F300 HydrophobicContact CE2-CE1 4.15Å; F84-F300 HydrophobicContact CE2-CE2 4.29Å; F84-F300 HydrophobicContact CE2-CG 4.21Å; F84-F300 HydrophobicContact CE2-CZ 4.2Å; F84-F300 HydrophobicContact CZ-CB 3.77Å; F84-F300 AromaticContact CZ-CD1 3.63Å; F84-F300 HydrophobicContact CZ-CD1 3.63Å; F84-F300 AromaticContact CZ-CD2 3.78Å; F84-F300 HydrophobicContact CZ-CD2 3.78Å; F84-F300 HydrophobicContact CZ-CE1 4.14Å; F84-F300 HydrophobicContact CZ-CE2 4.21Å; F84-F300 AromaticContact CZ-CG 3.44Å; F84-F300 HydrophobicContact CZ-CG 3.44Å; F84-F300 VanDerWaalsContact CZ-CG 3.44Å; F84-F300 HydrophobicContact CZ-CZ 4.38Å
85	L	98.1	Very high	96.2	Very high	0 Å²	0	24.8 Å²	24.8	0%	0	13%	0.129	C	C	.	.	H	α-helix	trans	-60.7	-31.7	-176.3	-71.9	162.7	0	0	0	112.2	I45 F46 F50 D81 L82 S87 L88 P89	I45-L85 HydrophobicContact CG2-CD2 3.93Å; F46-L85 HydrophobicContact CD2-CB 4.49Å; F46-L85 VanDerWaalsContact CD2-O 3.26Å; F46-L85 WeakPolarHBondContact CD2-O 3.28Å; F50-L85 HydrophobicContact CD2-CB 4.38Å; D81-L85 HydrophobicContact CB-CD1 4.42Å; D81-L85 WeakPolarHBondContact O-CB 3.34Å; D81-L85 WeakPolarHBondContact O-CD1 3.43Å; D81-L85 WeakPolarHBondContact O-CG 3.28Å; D81-L85 PolarHBondContact O-N 3.2Å; L82-L85 PolarHBondContact O-N 3.38Å; L85-S87 PolarHBondContact O-N 3.06Å; L85-L88 HydrophobicContact CD2-CD2 4.12Å; L85-L88 VanDerWaalsContact O-CB 3.26Å; L85-L88 WeakPolarHBondContact O-CB 3.4Å; L85-L88 PolarHBondContact O-N 2.83Å; L85-P89 WeakPolarHBondContact O-CD 3.36Å
86	I	97.4	Very high	96.2	Very high	87 Å²	87	26.3 Å²	26.3	45%	0.446	14%	0.14	S	C	.	.	H	α-helix	trans	-60.7	-29.7	173.2	-68.8	164.1	0	0	0	112.2	F50 L82 F84 L88 P89 F90	F50-I86 HydrophobicContact CE2-CD1 4.45Å; F50-I86 HydrophobicContact CE2-CG1 3.88Å; L82-I86 WeakPolarHBondContact O-CG1 3.42Å; L82-I86 PolarHBondContact O-N 3.01Å; L82-I86 VanDerWaalsContact O-N 3.11Å; F84-I86 PolarHBondContact O-N 3.31Å; I86-L88 VanDerWaalsContact C-N 3.35Å; I86-P89 WeakPolarHBondContact O-CD 3.08Å; I86-F90 WeakPolarHBondContact O-CE2 3.36Å
87	S	96.8	Very high	96	Very high	1 Å²	1	30.5 Å²	30.5	1%	0.007	16%	0.157	C	C	.	.	H	α-helix	trans	-78.3	-19.1	176.1	77.6	0	0	0	0	113.5	F84 L85 F90 W91	F84-S87 WeakPolarHBondContact O-CA 3.28Å; F84-S87 WeakPolarHBondContact O-CB 3.46Å; F84-S87 PolarHBondContact O-N 3.5Å; F84-S87 PolarHBondContact O-OG 3.28Å; L85-S87 PolarHBondContact O-N 3.06Å; S87-F90 WeakPolarHBondContact O-CB 3.39Å; S87-F90 PolarHBondContact O-N 3.16Å; S87-W91 PolarHBondContact O-N 2.81Å
88	L	96.1	Very high	95.7	Very high	1 Å²	1	35.2 Å²	35.2	1%	0.005	18%	0.183	C	C	.	.	H	α-helix	trans	-65	-38.1	-169.4	-153.8	62.5	0	0	0	114.6	Y42 I45 F46 F84 L85 I86 F90 W91 A92 F300	Y42-L88 HydrophobicContact CD1-CD1 4.33Å; Y42-L88 HydrophobicContact CD2-CD1 4.16Å; Y42-L88 HydrophobicContact CG-CD1 4.05Å; Y42-L88 HydrophobicContact CG-CG 4.21Å; Y42-L88 VanDerWaalsContact O-CD2 3.29Å; Y42-L88 WeakPolarHBondContact O-CD2 3.47Å; I45-L88 HydrophobicContact CB-CD2 3.78Å; I45-L88 HydrophobicContact CG2-CD2 3.49Å; I45-L88 VanDerWaalsContact CG2-CD2 3.49Å; F46-L88 HydrophobicContact CB-CD2 4.22Å; F84-L88 HydrophobicContact CE2-CD1 3.95Å; F84-L88 HydrophobicContact CZ-CD1 3.63Å; F84-L88 HydrophobicContact CZ-CD2 4.48Å; L85-L88 HydrophobicContact CD2-CD2 4.12Å; L85-L88 VanDerWaalsContact O-CB 3.26Å; L85-L88 WeakPolarHBondContact O-CB 3.4Å; L85-L88 PolarHBondContact O-N 2.83Å; I86-L88 VanDerWaalsContact C-N 3.35Å; L88-F90 VanDerWaalsContact C-N 3.28Å; L88-F90 PolarHBondContact O-N 3.47Å; L88-W91 PolarHBondContact O-N 3.45Å; L88-A92 PolarHBondContact O-N 2.89Å; L88-F300 HydrophobicContact CD1-CD2 3.69Å; L88-F300 HydrophobicContact CD1-CE2 4.01Å
89	P	97.2	Very high	95.4	Very high	45 Å²	45	36.7 Å²	36.7	29%	0.292	19%	0.188	S	C	.	.	H	α-helix	trans	-58.6	-36.7	172.9	-26.9	36.2	0	0	0	113.6	F46 L85 I86 A92 I93	F46-P89 HydrophobicContact CD1-CG 4.41Å; F46-P89 HydrophobicContact CD2-CG 3.9Å; F46-P89 HydrophobicContact CE1-CG 4.42Å; F46-P89 HydrophobicContact CE2-CG 3.91Å; F46-P89 HydrophobicContact CG-CG 4.15Å; F46-P89 HydrophobicContact CZ-CG 4.18Å; L85-P89 WeakPolarHBondContact O-CD 3.36Å; I86-P89 WeakPolarHBondContact O-CD 3.08Å; P89-A92 PolarHBondContact O-N 2.83Å; P89-I93 WeakPolarHBondContact O-CG1 3.45Å; P89-I93 PolarHBondContact O-N 3.26Å
90	F	97	Very high	95.2	Very high	62 Å²	62	35.4 Å²	35.4	27%	0.272	18%	0.182	S	C	.	.	H	α-helix	trans	-65.8	-40.8	177.7	-60.1	-88.4	0	0	0	111.3	I86 S87 L88 I93 Y94 W101 F103	I86-F90 WeakPolarHBondContact O-CE2 3.36Å; S87-F90 WeakPolarHBondContact O-CB 3.39Å; S87-F90 PolarHBondContact O-N 3.16Å; L88-F90 VanDerWaalsContact C-N 3.28Å; L88-F90 PolarHBondContact O-N 3.47Å; F90-I93 PolarHBondContact O-N 2.98Å; F90-Y94 WeakPolarHBondContact O-CB 3.21Å; F90-Y94 PolarHBondContact O-N 3.07Å; F90-W101 HydrophobicContact CB-CH2 3.87Å; F90-W101 HydrophobicContact CB-CZ3 4.33Å; F90-F103 HydrophobicContact CB-CD2 4.24Å; F90-F103 HydrophobicContact CB-CE2 4.06Å; F90-F103 AromaticContact CD1-CD1 3.76Å; F90-F103 HydrophobicContact CD1-CD1 3.76Å; F90-F103 AromaticContact CD1-CD2 3.85Å; F90-F103 HydrophobicContact CD1-CD2 3.85Å; F90-F103 AromaticContact CD1-CE1 3.8Å; F90-F103 HydrophobicContact CD1-CE1 3.8Å; F90-F103 AromaticContact CD1-CE2 3.9Å; F90-F103 HydrophobicContact CD1-CE2 3.9Å; F90-F103 AromaticContact CD1-CG 3.77Å; F90-F103 HydrophobicContact CD1-CG 3.77Å; F90-F103 AromaticContact CD1-CZ 3.87Å; F90-F103 HydrophobicContact CD1-CZ 3.87Å; F90-F103 HydrophobicContact CE1-CD1 4.05Å; F90-F103 HydrophobicContact CE1-CE1 4.19Å; F90-F103 HydrophobicContact CE1-CG 4.39Å; F90-F103 HydrophobicContact CG-CE2 4.49Å
91	W	95.6	Very high	95.1	Very high	18 Å²	18	35.7 Å²	35.7	7%	0.068	18%	0.183	C	C	.	.	H	α-helix	trans	-64.7	-42.3	172.3	-62.2	114.6	0	0	0	111.7	Y42 S87 L88 I93 Y94 Y95 W101 C111	Y42-W91 HydrophobicContact CD2-CB 3.91Å; Y42-W91 HydrophobicContact CE2-CB 3.79Å; S87-W91 PolarHBondContact O-N 2.81Å; L88-W91 PolarHBondContact O-N 3.45Å; W91-I93 VanDerWaalsContact C-N 3.33Å; W91-I93 PolarHBondContact O-N 2.94Å; W91-Y94 HydrophobicContact CE3-CD1 4.33Å; W91-Y94 WeakPolarHBondContact O-CB 3.4Å; W91-Y94 PolarHBondContact O-N 3.43Å; W91-Y95 VanDerWaalsContact O-CD2 3.23Å; W91-Y95 WeakPolarHBondContact O-CD2 3.39Å; W91-Y95 PolarHBondContact O-N 2.79Å; W91-W101 HydrophobicContact CD2-CZ3 4.34Å; W91-W101 AromaticContact CE3-CZ3 3.88Å; W91-W101 HydrophobicContact CE3-CZ3 3.88Å; W91-W101 HydrophobicContact CH2-CZ3 4.4Å; W91-W101 HydrophobicContact CZ3-CE3 4.42Å; W91-W101 AromaticContact CZ3-CZ3 3.91Å; W91-W101 HydrophobicContact CZ3-CZ3 3.91Å; W91-C111 HydrophobicContact CZ2-CB 3.7Å
92	A	95.4	Very high	94.9	Very high	8 Å²	8	40.3 Å²	40.3	7%	0.066	21%	0.206	C	C	.	.	H	α-helix	trans	-59.6	-44.4	177.6	0	0	0	0	0	111.6	P39 Y42 L88 P89 Y95 S96	P39-A92 HydrophobicContact CB-CB 4.25Å; P39-A92 WeakPolarHBondContact CG-O 3.48Å; Y42-A92 HydrophobicContact CD2-CB 4.4Å; L88-A92 PolarHBondContact O-N 2.89Å; P89-A92 PolarHBondContact O-N 2.83Å; A92-Y95 PolarHBondContact O-N 2.98Å; A92-S96 WeakPolarHBondContact O-CB 3.43Å; A92-S96 PolarHBondContact O-N 3.03Å; A92-S96 PolarHBondContact O-OG 3.42Å
93	I	95.4	Very high	94.8	Very high	61 Å²	61	42.3 Å²	42.3	31%	0.313	21%	0.214	S	C	.	.	H	α-helix	trans	-61.9	-46.9	175.5	-66.9	166.7	0	0	0	110.3	P89 F90 W91 Y95 S96 F97 M102 F103	P89-I93 WeakPolarHBondContact O-CG1 3.45Å; P89-I93 PolarHBondContact O-N 3.26Å; F90-I93 PolarHBondContact O-N 2.98Å; W91-I93 VanDerWaalsContact C-N 3.33Å; W91-I93 PolarHBondContact O-N 2.94Å; I93-Y95 VanDerWaalsContact C-N 3.33Å; I93-Y95 PolarHBondContact O-N 3.28Å; I93-S96 WeakPolarHBondContact CA-OG 3.28Å; I93-S96 PolarHBondContact O-N 3.33Å; I93-S96 PolarHBondContact O-OG 2.8Å; I93-F97 HydrophobicContact CG2-CD2 3.66Å; I93-F97 HydrophobicContact CG2-CE2 3.91Å; I93-F97 WeakPolarHBondContact O-CD2 3.07Å; I93-F97 PolarHBondContact O-N 2.84Å; I93-M102 HydrophobicContact CG2-CE 3.81Å; I93-F103 HydrophobicContact CB-CE2 4.15Å; I93-F103 HydrophobicContact CB-CZ 3.88Å; I93-F103 HydrophobicContact CD1-CE1 4.49Å; I93-F103 HydrophobicContact CD1-CZ 3.77Å; I93-F103 HydrophobicContact CG1-CZ 4.43Å; I93-F103 HydrophobicContact CG2-CE2 4.06Å; I93-F103 HydrophobicContact CG2-CZ 3.68Å
94	Y	93.7	Very high	94.7	Very high	17 Å²	17	40.7 Å²	40.7	7%	0.067	21%	0.214	C	C	.	.	H	α-helix	trans	-53	-46.3	176.3	168.1	-101.5	0	0	0	113.2	F90 W91 Y99 W101	F90-Y94 WeakPolarHBondContact O-CB 3.21Å; F90-Y94 PolarHBondContact O-N 3.07Å; W91-Y94 HydrophobicContact CE3-CD1 4.33Å; W91-Y94 WeakPolarHBondContact O-CB 3.4Å; W91-Y94 PolarHBondContact O-N 3.43Å; Y94-Y99 AromaticContact CE1-CD1 3.7Å; Y94-Y99 HydrophobicContact CE1-CD1 3.7Å; Y94-Y99 HydrophobicContact CE1-CG 4.46Å; Y94-Y99 WeakPolarHBondContact CE2-O 3.28Å; Y94-Y99 AromaticContact CZ-CD1 3.91Å; Y94-Y99 VanDerWaalsContact O-CA 3.22Å; Y94-Y99 WeakPolarHBondContact O-CA 3.05Å; Y94-Y99 PolarHBondContact O-N 2.86Å; Y94-W101 HydrophobicContact CD2-CB 3.88Å; Y94-W101 AromaticContact CD2-CE3 3.84Å; Y94-W101 HydrophobicContact CD2-CE3 3.84Å; Y94-W101 HydrophobicContact CE2-CB 4.16Å; Y94-W101 HydrophobicContact CG-CE3 4.02Å
95	Y	91.1	Very high	94.6	Very high	9 Å²	9	41.7 Å²	41.7	4%	0.035	23%	0.225	C	C	.	.	H	α-helix	trans	-71.7	-29.6	176.8	-79.6	-85.6	0	0	0	113	M1 N35 I38 Y42 W91 A92 I93 Y99	M1-Y95 HydrophobicContact CE-CE1 4.27Å; M1-Y95 HydrophobicContact SD-CE1 3.62Å; M1-Y95 PolarHBondContact SD-OH 3.42Å; N35-Y95 WeakPolarHBondContact CA-O 3.45Å; N35-Y95 WeakPolarHBondContact CB-O 3.22Å; I38-Y95 HydrophobicContact CB-CD1 4.17Å; I38-Y95 HydrophobicContact CB-CG 4.26Å; I38-Y95 HydrophobicContact CD1-CD1 3.76Å; I38-Y95 HydrophobicContact CD1-CE1 3.68Å; I38-Y95 HydrophobicContact CG2-CD1 3.82Å; I38-Y95 HydrophobicContact CG2-CD2 3.77Å; I38-Y95 HydrophobicContact CG2-CE1 4.04Å; I38-Y95 HydrophobicContact CG2-CE2 4.09Å; I38-Y95 HydrophobicContact CG2-CG 3.67Å; Y42-Y95 HydrophobicContact CD2-CD2 4.37Å; Y42-Y95 AromaticContact CE2-CD2 3.67Å; Y42-Y95 HydrophobicContact CE2-CD2 3.67Å; Y42-Y95 AromaticContact CE2-CE2 3.62Å; Y42-Y95 HydrophobicContact CE2-CE2 3.62Å; W91-Y95 VanDerWaalsContact O-CD2 3.23Å; W91-Y95 WeakPolarHBondContact O-CD2 3.39Å; W91-Y95 PolarHBondContact O-N 2.79Å; A92-Y95 PolarHBondContact O-N 2.98Å; I93-Y95 VanDerWaalsContact C-N 3.33Å; I93-Y95 PolarHBondContact O-N 3.28Å; Y95-Y99 HydrophobicContact CD1-CD1 4.1Å; Y95-Y99 AromaticContact CD1-CE1 3.43Å; Y95-Y99 HydrophobicContact CD1-CE1 3.43Å; Y95-Y99 VanDerWaalsContact CD1-CE1 3.43Å; Y95-Y99 AromaticContact CD1-CZ 3.93Å; Y95-Y99 HydrophobicContact CE1-CD1 4.15Å; Y95-Y99 AromaticContact CE1-CE1 3.36Å; Y95-Y99 HydrophobicContact CE1-CE1 3.36Å
96	S	92.8	Very high	94.6	Very high	54 Å²	54	48 Å²	48	38%	0.378	26%	0.258	S	S	.	.	H	α-helix	trans	-74.8	-26.4	178.7	68.9	0	0	0	0	113.9	A92 I93	A92-S96 WeakPolarHBondContact O-CB 3.43Å; A92-S96 PolarHBondContact O-N 3.03Å; A92-S96 PolarHBondContact O-OG 3.42Å; I93-S96 WeakPolarHBondContact CA-OG 3.28Å; I93-S96 PolarHBondContact O-N 3.33Å; I93-S96 PolarHBondContact O-OG 2.8Å
97	F	91.9	Very high	94.5	Very high	111 Å²	111	46.6 Å²	46.6	49%	0.487	25%	0.25	S	S	.	.	T	Hydrogen-bonded Turn	trans	-100.2	43.9	177	-77.5	-92.7	0	0	0	111.1	I93 Y99 N100 M102	I93-F97 HydrophobicContact CG2-CD2 3.66Å; I93-F97 HydrophobicContact CG2-CE2 3.91Å; I93-F97 WeakPolarHBondContact O-CD2 3.07Å; I93-F97 PolarHBondContact O-N 2.84Å; F97-Y99 VanDerWaalsContact C-N 3.28Å; F97-Y99 PolarHBondContact O-N 3.18Å; F97-Y99 VanDerWaalsContact O-N 3.14Å; F97-N100 HydrophobicContact CB-CB 4.35Å; F97-N100 WeakPolarHBondContact O-CB 3.48Å; F97-N100 PolarHBondContact O-N 3.45Å; F97-M102 HydrophobicContact CD1-CE 4.17Å; F97-M102 HydrophobicContact CD1-SD 4.47Å; F97-M102 HydrophobicContact CD2-CE 3.82Å; F97-M102 HydrophobicContact CE1-CE 4.3Å; F97-M102 HydrophobicContact CE2-CE 3.97Å; F97-M102 HydrophobicContact CG-CE 3.93Å; F97-M102 HydrophobicContact CZ-CE 4.2Å
98	D	88.7	Confident	94.6	Very high	99 Å²	99	46.6 Å²	46.6	53%	0.529	25%	0.25	S	C	.	.	T	Hydrogen-bonded Turn	trans	49.5	45.7	174.3	-56.2	-53.9	0	0	0	113.7	N35 N100	N35-D98 PolarHBondContact ND2-OD1 2.92Å; D98-N100 VanDerWaalsContact C-N 3.29Å; D98-N100 PolarHBondContact O-N 2.72Å
99	Y	89.5	Confident	94.6	Very high	31 Å²	31	49.3 Å²	49.3	12%	0.122	26%	0.262	C	S	.	.	T	Hydrogen-bonded Turn	trans	66.1	26.2	-179.7	-50.9	-91.7	0	0	0	114.3	M1 Q34 N35 Y94 Y95 F97	M1-Y99 HydrophobicContact CE-CE1 3.54Å; M1-Y99 VanDerWaalsContact CE-OH 3.31Å; M1-Y99 WeakPolarHBondContact CE-OH 2.96Å; M1-Y99 HydrophobicContact SD-CE1 3.75Å; Q34-Y99 PolarHBondContact OE1-OH 3.33Å; N35-Y99 VanDerWaalsContact OD1-CE2 3.29Å; N35-Y99 WeakPolarHBondContact OD1-CE2 3.36Å; Y94-Y99 AromaticContact CE1-CD1 3.7Å; Y94-Y99 HydrophobicContact CE1-CD1 3.7Å; Y94-Y99 HydrophobicContact CE1-CG 4.46Å; Y94-Y99 WeakPolarHBondContact CE2-O 3.28Å; Y94-Y99 AromaticContact CZ-CD1 3.91Å; Y94-Y99 VanDerWaalsContact O-CA 3.22Å; Y94-Y99 WeakPolarHBondContact O-CA 3.05Å; Y94-Y99 PolarHBondContact O-N 2.86Å; Y95-Y99 HydrophobicContact CD1-CD1 4.1Å; Y95-Y99 AromaticContact CD1-CE1 3.43Å; Y95-Y99 HydrophobicContact CD1-CE1 3.43Å; Y95-Y99 VanDerWaalsContact CD1-CE1 3.43Å; Y95-Y99 AromaticContact CD1-CZ 3.93Å; Y95-Y99 HydrophobicContact CE1-CD1 4.15Å; Y95-Y99 AromaticContact CE1-CE1 3.36Å; Y95-Y99 HydrophobicContact CE1-CE1 3.36Å; F97-Y99 VanDerWaalsContact C-N 3.28Å; F97-Y99 PolarHBondContact O-N 3.18Å; F97-Y99 VanDerWaalsContact O-N 3.14Å
100	N	92.7	Very high	94.7	Very high	46 Å²	46	51 Å²	51	25%	0.246	27%	0.268	C	S	.	.			trans	-92.8	116.5	173.3	-167.3	29.8	0	0	0	111.8	F97 D98 V184 T185	F97-N100 HydrophobicContact CB-CB 4.35Å; F97-N100 WeakPolarHBondContact O-CB 3.48Å; F97-N100 PolarHBondContact O-N 3.45Å; D98-N100 VanDerWaalsContact C-N 3.29Å; D98-N100 PolarHBondContact O-N 2.72Å; N100-V184 HydrophobicContact CB-CB 4.19Å; N100-V184 HydrophobicContact CB-CG1 4.14Å; N100-T185 PolarHBondContact OD1-N 3.03Å
101	W	95.6	Very high	94.7	Very high	6 Å²	6	48.2 Å²	48.2	2%	0.023	26%	0.256	C	S	.	.			trans	-90.6	105.7	178.4	-174.2	-90.6	0	0	0	111.5	F90 W91 Y94 F103 G104 M107 C108 C111 T176 T185 C187	F90-W101 HydrophobicContact CB-CH2 3.87Å; F90-W101 HydrophobicContact CB-CZ3 4.33Å; W91-W101 HydrophobicContact CD2-CZ3 4.34Å; W91-W101 AromaticContact CE3-CZ3 3.88Å; W91-W101 HydrophobicContact CE3-CZ3 3.88Å; W91-W101 HydrophobicContact CH2-CZ3 4.4Å; W91-W101 HydrophobicContact CZ3-CE3 4.42Å; W91-W101 AromaticContact CZ3-CZ3 3.91Å; W91-W101 HydrophobicContact CZ3-CZ3 3.91Å; Y94-W101 HydrophobicContact CD2-CB 3.88Å; Y94-W101 AromaticContact CD2-CE3 3.84Å; Y94-W101 HydrophobicContact CD2-CE3 3.84Å; Y94-W101 HydrophobicContact CE2-CB 4.16Å; Y94-W101 HydrophobicContact CG-CE3 4.02Å; W101-F103 HydrophobicContact CD2-CD2 4.09Å; W101-F103 AromaticContact CE2-CD2 3.87Å; W101-F103 HydrophobicContact CE3-CD2 4.27Å; W101-F103 HydrophobicContact CH2-CD2 4.04Å; W101-F103 HydrophobicContact CZ2-CB 3.9Å; W101-F103 AromaticContact CZ2-CD2 3.84Å; W101-F103 HydrophobicContact CZ2-CD2 3.84Å; W101-F103 HydrophobicContact CZ2-CG 4.32Å; W101-F103 HydrophobicContact CZ3-CD2 4.25Å; W101-G104 PolarHBondContact NE1-O 3.47Å; W101-M107 VanDerWaalsContact CZ2-C 3.49Å; W101-M107 HydrophobicContact CZ2-CB 3.88Å; W101-C108 HydrophobicContact CD2-CB 4.48Å; W101-C108 HydrophobicContact CZ2-CB 4.16Å; W101-C111 HydrophobicContact CH2-CB 4.05Å; W101-T176 HydrophobicContact CG-CG2 4.41Å; W101-T185 WeakPolarHBondContact CA-O 3.43Å; W101-T185 VanDerWaalsContact CB-O 3.24Å; W101-T185 WeakPolarHBondContact CB-O 3.28Å; W101-T185 PolarHBondContact N-O 3.33Å; W101-C187 HydrophobicContact CB-CB 3.96Å; W101-C187 HydrophobicContact CD2-CB 3.58Å; W101-C187 HydrophobicContact CE3-CB 3.72Å; W101-C187 HydrophobicContact CG-CB 3.67Å; W101-C187 HydrophobicContact CZ3-CB 4.49Å
102	M	95	Very high	94.7	Very high	98 Å²	98	47.5 Å²	47.5	48%	0.483	26%	0.255	S	S	.	.			trans	-95.5	-3.5	-174.3	-57.2	-176.4	-69.4	0	0	114.4	I93 F97	I93-M102 HydrophobicContact CG2-CE 3.81Å; F97-M102 HydrophobicContact CD1-CE 4.17Å; F97-M102 HydrophobicContact CD1-SD 4.47Å; F97-M102 HydrophobicContact CD2-CE 3.82Å; F97-M102 HydrophobicContact CE1-CE 4.3Å; F97-M102 HydrophobicContact CE2-CE 3.97Å; F97-M102 HydrophobicContact CG-CE 3.93Å; F97-M102 HydrophobicContact CZ-CE 4.2Å
103	F	96.1	Very high	94.8	Very high	62 Å²	62	47.6 Å²	47.6	27%	0.272	26%	0.255	S	S	.	.	S	Bend	trans	-94.8	7	-169.1	-49.9	-73.8	0	0	0	114.4	F90 I93 W101 M107	F90-F103 HydrophobicContact CB-CD2 4.24Å; F90-F103 HydrophobicContact CB-CE2 4.06Å; F90-F103 AromaticContact CD1-CD1 3.76Å; F90-F103 HydrophobicContact CD1-CD1 3.76Å; F90-F103 AromaticContact CD1-CD2 3.85Å; F90-F103 HydrophobicContact CD1-CD2 3.85Å; F90-F103 AromaticContact CD1-CE1 3.8Å; F90-F103 HydrophobicContact CD1-CE1 3.8Å; F90-F103 AromaticContact CD1-CE2 3.9Å; F90-F103 HydrophobicContact CD1-CE2 3.9Å; F90-F103 AromaticContact CD1-CG 3.77Å; F90-F103 HydrophobicContact CD1-CG 3.77Å; F90-F103 AromaticContact CD1-CZ 3.87Å; F90-F103 HydrophobicContact CD1-CZ 3.87Å; F90-F103 HydrophobicContact CE1-CD1 4.05Å; F90-F103 HydrophobicContact CE1-CE1 4.19Å; F90-F103 HydrophobicContact CE1-CG 4.39Å; F90-F103 HydrophobicContact CG-CE2 4.49Å; I93-F103 HydrophobicContact CB-CE2 4.15Å; I93-F103 HydrophobicContact CB-CZ 3.88Å; I93-F103 HydrophobicContact CD1-CE1 4.49Å; I93-F103 HydrophobicContact CD1-CZ 3.77Å; I93-F103 HydrophobicContact CG1-CZ 4.43Å; I93-F103 HydrophobicContact CG2-CE2 4.06Å; I93-F103 HydrophobicContact CG2-CZ 3.68Å; W101-F103 HydrophobicContact CD2-CD2 4.09Å; W101-F103 AromaticContact CE2-CD2 3.87Å; W101-F103 HydrophobicContact CE3-CD2 4.27Å; W101-F103 HydrophobicContact CH2-CD2 4.04Å; W101-F103 HydrophobicContact CZ2-CB 3.9Å; W101-F103 AromaticContact CZ2-CD2 3.84Å; W101-F103 HydrophobicContact CZ2-CD2 3.84Å; W101-F103 HydrophobicContact CZ2-CG 4.32Å; W101-F103 HydrophobicContact CZ3-CD2 4.25Å; F103-M107 HydrophobicContact CB-CB 3.67Å; F103-M107 HydrophobicContact CB-CG 4.08Å; F103-M107 WeakPolarHBondContact O-CB 3.49Å; F103-M107 WeakPolarHBondContact O-CG 3.17Å
104	G	95.5	Very high	95	Very high	37 Å²	37	46.1 Å²	46.1	38%	0.381	25%	0.247	S	C	.	.	H	α-helix	trans	73.6	172.8	-179.3	0	0	0	0	0	115	W101 L106 M107 C108	W101-G104 PolarHBondContact NE1-O 3.47Å; G104-L106 PolarHBondContact O-N 3.48Å; G104-M107 PolarHBondContact O-N 3.01Å; G104-C108 PolarHBondContact O-N 3.26Å
105	G	95.7	Very high	95.1	Very high	22 Å²	22	46.9 Å²	46.9	23%	0.227	25%	0.252	C	S	.	.	H	α-helix	trans	-63.5	-38.2	-174.2	0	0	0	0	0	114.4	M107 C108 K109	G105-M107 PolarHBondContact O-N 2.98Å; G105-C108 WeakPolarHBondContact O-CB 3.24Å; G105-C108 PolarHBondContact O-N 3.4Å; G105-K109 PolarHBondContact O-N 3.19Å
106	L	96.3	Very high	95.3	Very high	132 Å²	132	46.9 Å²	46.9	69%	0.691	25%	0.253	S	S	*	.	H	α-helix	trans	-60.6	-48.3	179.4	178.2	62.8	0	0	0	111.8	G104 C108 K109 L110	G104-L106 PolarHBondContact O-N 3.48Å; L106-C108 VanDerWaalsContact C-N 3.32Å; L106-C108 PolarHBondContact O-N 2.92Å; L106-K109 PolarHBondContact O-N 3.07Å; L106-L110 WeakPolarHBondContact O-CB 3.48Å; L106-L110 PolarHBondContact O-N 2.91Å
107	M	97.1	Very high	95.5	Very high	59 Å²	59	45.8 Å²	45.8	29%	0.291	24%	0.243	S	C	.	.	H	α-helix	trans	-68.8	-33	179.2	-69.5	-65.1	138.4	0	0	111.8	W101 F103 G104 G105 K109 L110 C111	W101-M107 VanDerWaalsContact CZ2-C 3.49Å; W101-M107 HydrophobicContact CZ2-CB 3.88Å; F103-M107 HydrophobicContact CB-CB 3.67Å; F103-M107 HydrophobicContact CB-CG 4.08Å; F103-M107 WeakPolarHBondContact O-CB 3.49Å; F103-M107 WeakPolarHBondContact O-CG 3.17Å; G104-M107 PolarHBondContact O-N 3.01Å; G105-M107 PolarHBondContact O-N 2.98Å; M107-K109 VanDerWaalsContact C-N 3.35Å; M107-L110 HydrophobicContact CE-CD2 4.19Å; M107-L110 PolarHBondContact O-N 3.04Å; M107-L110 HydrophobicContact SD-CD2 4.13Å; M107-C111 VanDerWaalsContact O-CB 3.26Å; M107-C111 WeakPolarHBondContact O-CB 3.29Å; M107-C111 PolarHBondContact O-N 3.25Å; M107-C111 PolarHBondContact O-SG 3.05Å
108	C	97.4	Very high	95.8	Very high	0 Å²	0	40.6 Å²	40.6	0%	0	22%	0.22	C	C	.	.	H	α-helix	trans	-60.1	-45.9	174.6	173.6	0	0	0	0	111.2	W101 G104 G105 L106 G112 R174 T176 C187	W101-C108 HydrophobicContact CD2-CB 4.48Å; W101-C108 HydrophobicContact CZ2-CB 4.16Å; G104-C108 PolarHBondContact O-N 3.26Å; G105-C108 WeakPolarHBondContact O-CB 3.24Å; G105-C108 PolarHBondContact O-N 3.4Å; L106-C108 VanDerWaalsContact C-N 3.32Å; L106-C108 PolarHBondContact O-N 2.92Å; C108-G112 PolarHBondContact O-N 2.71Å; C108-G112 VanDerWaalsContact O-N 3.11Å; C108-R174 VanDerWaalsContact SG-CG 3.59Å; C108-T176 HydrophobicContact CB-CG2 4.03Å; C108-C187 WeakPolarHBondContact CA-SG 3.3Å; C108-C187 HydrophobicContact CB-CB 3.88Å; C108-C187 WeakPolarHBondContact CB-SG 3.41Å; C108-C187 WeakPolarHBondContact SG-CA 3.26Å; C108-C187 WeakPolarHBondContact SG-CB 3.46Å; C108-C187 CovalentContact SG-SG 2.03Å; C108-C187 PolarHBondContact SG-SG 3.44Å
109	K	97.4	Very high	96.1	Very high	59 Å²	59	36.3 Å²	36.3	26%	0.257	20%	0.198	S	C	.	.	H	α-helix	trans	-63.6	-52.3	174.5	-73.7	176.6	-177.8	175	0	111.2	G105 L106 M107 C111 G112 C113 R174 D175	G105-K109 PolarHBondContact O-N 3.19Å; L106-K109 PolarHBondContact O-N 3.07Å; M107-K109 VanDerWaalsContact C-N 3.35Å; K109-C111 PolarHBondContact O-N 3.42Å; K109-G112 PolarHBondContact O-N 3.39Å; K109-C113 WeakPolarHBondContact O-CB 3.49Å; K109-C113 PolarHBondContact O-N 2.83Å; K109-C113 PolarHBondContact O-SG 3.39Å; K109-R174 WeakPolarHBondContact CE-O 3.33Å; K109-R174 WeakPolarHBondContact CG-O 3.42Å; K109-D175 WeakPolarHBondContact CE-OD2 3.23Å; K109-D175 IonicContact NZ-OD2 2.81Å; K109-D175 PolarHBondContact NZ-OD2 3.27Å
110	L	97.8	Very high	96.5	Very high	80 Å²	80	35.3 Å²	35.3	42%	0.419	19%	0.194	S	C	.	.	H	α-helix	trans	-59	-50	-177.5	-176.4	64.3	0	0	0	112.2	L106 M107 G112 C113 L114	L106-L110 WeakPolarHBondContact O-CB 3.48Å; L106-L110 PolarHBondContact O-N 2.91Å; M107-L110 HydrophobicContact CE-CD2 4.19Å; M107-L110 PolarHBondContact O-N 3.04Å; M107-L110 HydrophobicContact SD-CD2 4.13Å; L110-G112 VanDerWaalsContact C-N 3.33Å; L110-G112 PolarHBondContact O-N 2.99Å; L110-C113 PolarHBondContact O-N 3.49Å; L110-L114 HydrophobicContact CD1-CD1 4.44Å; L110-L114 HydrophobicContact CD1-CG 4.43Å; L110-L114 HydrophobicContact CG-CD1 4.12Å; L110-L114 VanDerWaalsContact O-CG 3.31Å; L110-L114 WeakPolarHBondContact O-CG 3.43Å; L110-L114 PolarHBondContact O-N 3.33Å
111	C	97.6	Very high	96.8	Very high	3 Å²	3	33.1 Å²	33.1	2%	0.02	18%	0.182	C	C	.	.	H	α-helix	trans	-63.3	-40	179.1	-66.5	0	0	0	0	111.6	W91 W101 M107 K109 L115	W91-C111 HydrophobicContact CZ2-CB 3.7Å; W101-C111 HydrophobicContact CH2-CB 4.05Å; M107-C111 VanDerWaalsContact O-CB 3.26Å; M107-C111 WeakPolarHBondContact O-CB 3.29Å; M107-C111 PolarHBondContact O-N 3.25Å; M107-C111 PolarHBondContact O-SG 3.05Å; K109-C111 PolarHBondContact O-N 3.42Å; C111-L115 PolarHBondContact O-N 3.22Å; C111-L115 VanDerWaalsContact O-N 3.14Å
112	G	96.3	Very high	96.8	Very high	4 Å²	4	32.9 Å²	32.9	4%	0.041	18%	0.181	C	C	.	.	H	α-helix	trans	-62.4	-42.7	174.1	0	0	0	0	0	112.4	C108 K109 L110 L115 S116	C108-G112 PolarHBondContact O-N 2.71Å; C108-G112 VanDerWaalsContact O-N 3.11Å; K109-G112 PolarHBondContact O-N 3.39Å; L110-G112 VanDerWaalsContact C-N 3.33Å; L110-G112 PolarHBondContact O-N 2.99Å; G112-L115 PolarHBondContact O-N 3.44Å; G112-S116 WeakPolarHBondContact O-CB 3.27Å; G112-S116 PolarHBondContact O-N 3.33Å
113	C	97.8	Very high	96.9	Very high	10 Å²	10	28.2 Å²	28.2	7%	0.068	16%	0.158	C	C	.	.	H	α-helix	trans	-66.9	-42.6	177.6	-72.7	0	0	0	0	112.6	K109 L110 L115 S116 L117 T167 M171	K109-C113 WeakPolarHBondContact O-CB 3.49Å; K109-C113 PolarHBondContact O-N 2.83Å; K109-C113 PolarHBondContact O-SG 3.39Å; L110-C113 PolarHBondContact O-N 3.49Å; C113-L115 VanDerWaalsContact C-N 3.29Å; C113-L115 PolarHBondContact O-N 3.22Å; C113-S116 PolarHBondContact O-N 2.93Å; C113-L117 WeakPolarHBondContact O-CB 3.28Å; C113-L117 PolarHBondContact O-N 3.46Å; C113-T167 HydrophobicContact CB-CG2 3.64Å; C113-M171 HydrophobicContact CB-CE 4.41Å
114	L	98.1	Very high	97	Very high	30 Å²	30	26.9 Å²	26.9	16%	0.157	15%	0.152	C	C	.	.	H	α-helix	trans	-60.7	-40.5	176.5	-70.6	169.9	0	0	0	111.6	L83 L110 N118	L83-L114 HydrophobicContact CB-CD2 4.09Å; L110-L114 HydrophobicContact CD1-CD1 4.44Å; L110-L114 HydrophobicContact CD1-CG 4.43Å; L110-L114 HydrophobicContact CG-CD1 4.12Å; L110-L114 VanDerWaalsContact O-CG 3.31Å; L110-L114 WeakPolarHBondContact O-CG 3.43Å; L110-L114 PolarHBondContact O-N 3.33Å; L114-N118 WeakPolarHBondContact O-CB 3.29Å; L114-N118 PolarHBondContact O-N 2.92Å
115	L	95.9	Very high	97.1	Very high	33 Å²	33	25.1 Å²	25.1	17%	0.173	13%	0.134	C	C	.	.	H	α-helix	trans	-61.7	-52.5	172.5	168.6	58.6	0	0	0	111.8	F84 C111 G112 C113 L117 N118 V119 F300	F84-L115 HydrophobicContact CD2-CB 4.25Å; F84-L115 HydrophobicContact CD2-CD1 4.01Å; F84-L115 HydrophobicContact CE2-CD1 3.79Å; C111-L115 PolarHBondContact O-N 3.22Å; C111-L115 VanDerWaalsContact O-N 3.14Å; G112-L115 PolarHBondContact O-N 3.44Å; C113-L115 VanDerWaalsContact C-N 3.29Å; C113-L115 PolarHBondContact O-N 3.22Å; L115-L117 VanDerWaalsContact C-N 3.33Å; L115-L117 PolarHBondContact O-N 3.35Å; L115-N118 PolarHBondContact O-N 3.37Å; L115-V119 HydrophobicContact CD1-CG2 4.31Å; L115-V119 WeakPolarHBondContact O-CG2 3.49Å; L115-V119 PolarHBondContact O-N 2.99Å; L115-V119 VanDerWaalsContact O-N 3.11Å; L115-F300 HydrophobicContact CD1-CD1 4.06Å; L115-F300 HydrophobicContact CD1-CE1 3.21Å; L115-F300 HydrophobicContact CD1-CZ 3.69Å; L115-F300 HydrophobicContact CD2-CE1 4.06Å; L115-F300 HydrophobicContact CD2-CZ 3.77Å; L115-F300 HydrophobicContact CG-CE1 4.27Å; L115-F300 HydrophobicContact CG-CZ 4.37Å
116	S	96.1	Very high	97.1	Very high	8 Å²	8	24.1 Å²	24.1	6%	0.056	12%	0.123	C	C	.	.	H	α-helix	trans	-60.9	-44	-178.4	-158	0	0	0	0	111.5	G112 C113 N118 V119 Y120 T170	G112-S116 WeakPolarHBondContact O-CB 3.27Å; G112-S116 PolarHBondContact O-N 3.33Å; C113-S116 PolarHBondContact O-N 2.93Å; S116-N118 PolarHBondContact O-N 3.33Å; S116-V119 PolarHBondContact O-N 3.16Å; S116-Y120 WeakPolarHBondContact O-CD2 3.44Å; S116-Y120 PolarHBondContact O-N 3.17Å; S116-T170 PolarHBondContact OG-OG1 3.35Å; S116-T170 VanDerWaalsContact OG-OG1 3.07Å
117	L	97.9	Very high	97.1	Very high	32 Å²	32	18.7 Å²	18.7	17%	0.168	10%	0.095	C	C	.	.	H	α-helix	trans	-59.1	-45.1	176.7	-176.7	70.7	0	0	0	111.4	C113 L115 Y120 A121 W160 A163 T167	C113-L117 WeakPolarHBondContact O-CB 3.28Å; C113-L117 PolarHBondContact O-N 3.46Å; L115-L117 VanDerWaalsContact C-N 3.33Å; L115-L117 PolarHBondContact O-N 3.35Å; L117-Y120 PolarHBondContact O-N 2.95Å; L117-A121 WeakPolarHBondContact O-CB 3.4Å; L117-A121 PolarHBondContact O-N 2.9Å; L117-W160 HydrophobicContact CD1-CE3 4.31Å; L117-W160 HydrophobicContact CD1-CZ3 4.38Å; L117-W160 HydrophobicContact CD2-CE3 4.43Å; L117-W160 HydrophobicContact CD2-CZ3 3.9Å; L117-W160 HydrophobicContact CG-CE3 4.49Å; L117-W160 HydrophobicContact CG-CZ3 4.07Å; L117-A163 HydrophobicContact CD1-CB 3.79Å; L117-T167 WeakPolarHBondContact CA-OG1 3.4Å; L117-T167 PolarHBondContact N-OG1 2.93Å
118	N	97.6	Very high	97	Very high	1 Å²	1	17.3 Å²	17.3	1%	0.005	9%	0.091	C	C	.	.	H	α-helix	trans	-61.2	-46.1	177.6	174.4	-85.2	0	0	0	111.9	S80 D81 F84 L114 L115 S116 Y120 A121 S122	S80-N118 PolarHBondContact O-ND2 3.35Å; D81-N118 WeakPolarHBondContact CA-ND2 3.45Å; D81-N118 PolarHBondContact N-ND2 2.84Å; D81-N118 PolarHBondContact OD1-ND2 2.85Å; F84-N118 HydrophobicContact CB-CB 3.5Å; F84-N118 HydrophobicContact CG-CB 4.14Å; L114-N118 WeakPolarHBondContact O-CB 3.29Å; L114-N118 PolarHBondContact O-N 2.92Å; L115-N118 PolarHBondContact O-N 3.37Å; S116-N118 PolarHBondContact O-N 3.33Å; N118-Y120 VanDerWaalsContact C-N 3.32Å; N118-Y120 PolarHBondContact O-N 3.36Å; N118-A121 PolarHBondContact O-N 2.67Å; N118-S122 PolarHBondContact ND2-OG 2.84Å; N118-S122 WeakPolarHBondContact O-CB 3.37Å; N118-S122 PolarHBondContact O-N 2.84Å; N118-S122 PolarHBondContact O-OG 3.05Å
119	V	95.5	Very high	96.7	Very high	9 Å²	9	17.6 Å²	17.6	6%	0.055	9%	0.093	C	C	.	.	H	α-helix	trans	-54	-50.5	179.7	170.7	0	0	0	0	111	L115 S116 I123 A210 W261	L115-V119 HydrophobicContact CD1-CG2 4.31Å; L115-V119 WeakPolarHBondContact O-CG2 3.49Å; L115-V119 PolarHBondContact O-N 2.99Å; L115-V119 VanDerWaalsContact O-N 3.11Å; S116-V119 PolarHBondContact O-N 3.16Å; V119-I123 VanDerWaalsContact O-CG2 3.3Å; V119-I123 WeakPolarHBondContact O-CG2 3.5Å; V119-I123 PolarHBondContact O-N 3.48Å; V119-A210 HydrophobicContact CG1-CB 3.84Å; V119-W261 HydrophobicContact CG2-CH2 3.35Å; V119-W261 HydrophobicContact CG2-CZ2 3.84Å; V119-W261 HydrophobicContact CG2-CZ3 3.76Å
120	Y	97.8	Very high	96.5	Very high	11 Å²	11	14.8 Å²	14.8	4%	0.043	8%	0.08	C	C	.	.	H	α-helix	trans	-72.2	-48.2	-179.2	-67.6	-67.1	0	0	0	112.8	S116 L117 N118 S122 I123 Y124 M166 L209 A210	S116-Y120 WeakPolarHBondContact O-CD2 3.44Å; S116-Y120 PolarHBondContact O-N 3.17Å; L117-Y120 PolarHBondContact O-N 2.95Å; N118-Y120 VanDerWaalsContact C-N 3.32Å; N118-Y120 PolarHBondContact O-N 3.36Å; Y120-S122 VanDerWaalsContact C-N 3.34Å; Y120-S122 PolarHBondContact O-N 3.02Å; Y120-I123 WeakPolarHBondContact O-CG2 3.31Å; Y120-Y124 HydrophobicContact CD1-CE2 4.31Å; Y120-Y124 WeakPolarHBondContact O-CB 3.29Å; Y120-Y124 WeakPolarHBondContact O-CD2 3.35Å; Y120-Y124 PolarHBondContact O-N 3.34Å; Y120-Y124 VanDerWaalsContact O-N 3.09Å; Y120-M166 HydrophobicContact CD1-CB 4.03Å; Y120-M166 HydrophobicContact CD1-CG 4.28Å; Y120-M166 HydrophobicContact CD2-CB 3.56Å; Y120-M166 HydrophobicContact CE1-CB 3.97Å; Y120-M166 HydrophobicContact CE1-CG 4.28Å; Y120-M166 HydrophobicContact CE2-CB 3.5Å; Y120-M166 HydrophobicContact CG-CB 3.84Å; Y120-M166 HydrophobicContact CG-CG 4.44Å; Y120-L209 HydrophobicContact CE1-CB 4.26Å; Y120-A210 HydrophobicContact CD1-CB 3.91Å; Y120-A210 HydrophobicContact CE1-CB 3.71Å
121	A	98.1	Very high	96.3	Very high	0 Å²	0	12.9 Å²	12.9	0%	0	7%	0.072	C	C	.	.	H	α-helix	trans	-60.2	-46.5	-178.5	0	0	0	0	0	110.9	L117 N118 I123 Y124 F125 W160 A163	L117-A121 WeakPolarHBondContact O-CB 3.4Å; L117-A121 PolarHBondContact O-N 2.9Å; N118-A121 PolarHBondContact O-N 2.67Å; A121-I123 PolarHBondContact O-N 3.28Å; A121-Y124 PolarHBondContact O-N 2.9Å; A121-F125 HydrophobicContact CB-CD2 4.43Å; A121-F125 HydrophobicContact CB-CE2 4.34Å; A121-F125 WeakPolarHBondContact O-CD2 3.48Å; A121-F125 PolarHBondContact O-N 2.84Å; A121-W160 HydrophobicContact CB-CE3 4.47Å; A121-W160 HydrophobicContact CB-CZ3 4.18Å; A121-A163 HydrophobicContact CB-CB 4.03Å
122	S	96.8	Very high	95.8	Very high	0 Å²	0	13.4 Å²	13.4	0%	0	8%	0.075	C	C	.	.	H	α-helix	trans	-60.7	-48.8	-176.3	-66.4	0	0	0	0	112	L77 S80 N118 Y120 Y124 F125 I126	L77-S122 VanDerWaalsContact CD1-CA 3.45Å; L77-S122 WeakPolarHBondContact CD1-OG 3.26Å; S80-S122 PolarHBondContact OG-OG 3.11Å; N118-S122 PolarHBondContact ND2-OG 2.84Å; N118-S122 WeakPolarHBondContact O-CB 3.37Å; N118-S122 PolarHBondContact O-N 2.84Å; N118-S122 PolarHBondContact O-OG 3.05Å; Y120-S122 VanDerWaalsContact C-N 3.34Å; Y120-S122 PolarHBondContact O-N 3.02Å; S122-Y124 PolarHBondContact O-N 3.28Å; S122-F125 PolarHBondContact O-N 2.88Å; S122-I126 VanDerWaalsContact O-CG1 3.26Å; S122-I126 WeakPolarHBondContact O-CG1 3.36Å; S122-I126 PolarHBondContact O-N 3.21Å
123	I	97	Very high	95.5	Very high	0 Å²	0	13.7 Å²	13.7	0%	0	7%	0.074	C	C	.	.	H	α-helix	trans	-69.4	-34.1	-179.5	-168.1	46.3	0	0	0	112.8	V119 Y120 A121 I126 T127 P214 I218 F257	V119-I123 VanDerWaalsContact O-CG2 3.3Å; V119-I123 WeakPolarHBondContact O-CG2 3.5Å; V119-I123 PolarHBondContact O-N 3.48Å; Y120-I123 WeakPolarHBondContact O-CG2 3.31Å; A121-I123 PolarHBondContact O-N 3.28Å; I123-I126 HydrophobicContact CD1-CB 4.37Å; I123-I126 HydrophobicContact CD1-CG2 4.49Å; I123-I126 PolarHBondContact O-N 3.41Å; I123-T127 WeakPolarHBondContact O-CB 3.42Å; I123-T127 PolarHBondContact O-N 3.45Å; I123-T127 PolarHBondContact O-OG1 3.41Å; I123-P214 HydrophobicContact CD1-CB 3.82Å; I123-P214 HydrophobicContact CG1-CB 3.35Å; I123-P214 HydrophobicContact CG1-CG 3.66Å; I123-P214 HydrophobicContact CG2-CG 4.18Å; I123-I218 HydrophobicContact CD1-CD1 3.96Å; I123-F257 HydrophobicContact CB-CE1 4.15Å; I123-F257 HydrophobicContact CB-CE2 3.75Å; I123-F257 HydrophobicContact CB-CZ 3.49Å; I123-F257 VanDerWaalsContact CB-CZ 3.49Å; I123-F257 HydrophobicContact CD1-CD1 3.52Å; I123-F257 HydrophobicContact CD1-CD2 4.24Å; I123-F257 HydrophobicContact CD1-CE1 3.27Å; I123-F257 HydrophobicContact CD1-CE2 4.02Å; I123-F257 HydrophobicContact CD1-CG 4.03Å; I123-F257 HydrophobicContact CD1-CZ 3.56Å; I123-F257 HydrophobicContact CG1-CD1 4.41Å; I123-F257 HydrophobicContact CG1-CE1 3.68Å; I123-F257 HydrophobicContact CG1-CE2 4.19Å; I123-F257 HydrophobicContact CG1-CZ 3.56Å
124	Y	98.1	Very high	95.1	Very high	35 Å²	35	14.5 Å²	14.5	14%	0.137	8%	0.076	C	C	.	.	H	α-helix	trans	-68.7	-39.2	175.5	-64.3	-21.8	0	0	0	111.9	Y120 A121 S122 T127 C128 I159 I162 L209 P214	Y120-Y124 HydrophobicContact CD1-CE2 4.31Å; Y120-Y124 WeakPolarHBondContact O-CB 3.29Å; Y120-Y124 WeakPolarHBondContact O-CD2 3.35Å; Y120-Y124 PolarHBondContact O-N 3.34Å; Y120-Y124 VanDerWaalsContact O-N 3.09Å; A121-Y124 PolarHBondContact O-N 2.9Å; S122-Y124 PolarHBondContact O-N 3.28Å; Y124-T127 PolarHBondContact O-N 2.85Å; Y124-C128 PolarHBondContact O-N 2.93Å; Y124-C128 PolarHBondContact O-SG 3.34Å; Y124-I159 HydrophobicContact CD2-CG2 4.42Å; Y124-I162 HydrophobicContact CD2-CG2 4.42Å; Y124-I162 HydrophobicContact CE2-CG2 3.77Å; Y124-L209 WeakPolarHBondContact CE1-O 3.31Å; Y124-L209 PolarHBondContact OH-O 3.3Å; Y124-L209 VanDerWaalsContact OH-O 3.07Å; Y124-P214 HydrophobicContact CD1-CG 4.39Å; Y124-P214 HydrophobicContact CE1-CG 4.12Å
125	F	96.8	Very high	94.6	Very high	0 Å²	0	18.6 Å²	18.6	0%	0	9%	0.09	C	C	.	.	H	α-helix	trans	-63.8	-41.5	171.4	-77.4	-60.8	0	0	0	112.1	Y73 N76 L77 A121 S122 T127 C128 M129 I159 W160	Y73-F125 AromaticContact CD1-CD1 3.91Å; Y73-F125 HydrophobicContact CD1-CD1 3.91Å; Y73-F125 HydrophobicContact CD1-CE1 4.15Å; Y73-F125 HydrophobicContact CG-CD1 4.44Å; N76-F125 HydrophobicContact CB-CD1 3.99Å; N76-F125 HydrophobicContact CB-CD2 4.08Å; N76-F125 HydrophobicContact CB-CE1 3.46Å; N76-F125 VanDerWaalsContact CB-CE1 3.46Å; N76-F125 HydrophobicContact CB-CE2 3.58Å; N76-F125 HydrophobicContact CB-CG 4.31Å; N76-F125 HydrophobicContact CB-CZ 3.27Å; L77-F125 HydrophobicContact CB-CB 4.36Å; A121-F125 HydrophobicContact CB-CD2 4.43Å; A121-F125 HydrophobicContact CB-CE2 4.34Å; A121-F125 WeakPolarHBondContact O-CD2 3.48Å; A121-F125 PolarHBondContact O-N 2.84Å; S122-F125 PolarHBondContact O-N 2.88Å; F125-T127 VanDerWaalsContact C-N 3.32Å; F125-T127 PolarHBondContact O-N 3.31Å; F125-C128 PolarHBondContact O-N 3.22Å; F125-M129 VanDerWaalsContact O-CG 3.32Å; F125-M129 WeakPolarHBondContact O-CG 3.5Å; F125-M129 PolarHBondContact O-N 3.35Å; F125-I159 HydrophobicContact CD1-CD1 3.63Å; F125-I159 HydrophobicContact CD2-CG2 4.01Å; F125-I159 HydrophobicContact CE1-CB 4.26Å; F125-I159 HydrophobicContact CE1-CD1 3.55Å; F125-I159 HydrophobicContact CE1-CG2 4.18Å; F125-I159 HydrophobicContact CE2-CB 4.42Å; F125-I159 HydrophobicContact CE2-CG2 3.6Å; F125-I159 HydrophobicContact CG-CD1 4.3Å; F125-I159 HydrophobicContact CG-CG2 4.41Å; F125-I159 HydrophobicContact CZ-CB 3.97Å; F125-I159 HydrophobicContact CZ-CD1 4.14Å; F125-I159 HydrophobicContact CZ-CG2 3.67Å; F125-W160 HydrophobicContact CE2-CZ2 4.31Å; F125-W160 AromaticContact CZ-NE1 3.82Å
126	I	94.9	Very high	94	Very high	0 Å²	0	17.6 Å²	17.6	0%	0	9%	0.086	C	C	.	.	H	α-helix	trans	-62.2	-40.4	174.9	-67	169.2	0	0	0	111.7	L77 S122 I123 M129 S130 I218 V253 V254 F257	L77-I126 HydrophobicContact CD2-CG1 4.01Å; S122-I126 VanDerWaalsContact O-CG1 3.26Å; S122-I126 WeakPolarHBondContact O-CG1 3.36Å; S122-I126 PolarHBondContact O-N 3.21Å; I123-I126 HydrophobicContact CD1-CB 4.37Å; I123-I126 HydrophobicContact CD1-CG2 4.49Å; I123-I126 PolarHBondContact O-N 3.41Å; I126-M129 HydrophobicContact CB-CE 4.27Å; I126-M129 HydrophobicContact CG1-CE 3.8Å; I126-M129 PolarHBondContact O-N 3.46Å; I126-S130 PolarHBondContact O-N 2.97Å; I126-S130 PolarHBondContact O-OG 3.34Å; I126-I218 HydrophobicContact CG2-CD1 3.97Å; I126-V253 HydrophobicContact CD1-CG1 3.86Å; I126-V253 HydrophobicContact CG1-CG1 3.84Å; I126-V254 HydrophobicContact CG2-CG2 3.59Å; I126-F257 HydrophobicContact CD1-CB 3.84Å; I126-F257 HydrophobicContact CD1-CD2 3.65Å; I126-F257 HydrophobicContact CD1-CG 3.92Å
127	T	96.5	Very high	93.5	Very high	18 Å²	18	18.2 Å²	18.2	11%	0.11	9%	0.088	C	C	.	.	H	α-helix	trans	-62.2	-48.2	175.4	-56.1	0	0	0	0	110.9	I123 Y124 F125 M129 S130 V131 V217 I218	I123-T127 WeakPolarHBondContact O-CB 3.42Å; I123-T127 PolarHBondContact O-N 3.45Å; I123-T127 PolarHBondContact O-OG1 3.41Å; Y124-T127 PolarHBondContact O-N 2.85Å; F125-T127 VanDerWaalsContact C-N 3.32Å; F125-T127 PolarHBondContact O-N 3.31Å; T127-M129 VanDerWaalsContact C-N 3.34Å; T127-M129 PolarHBondContact O-N 3.01Å; T127-S130 WeakPolarHBondContact O-CB 3.32Å; T127-S130 PolarHBondContact O-N 3.26Å; T127-S130 VanDerWaalsContact O-N 3.13Å; T127-V131 WeakPolarHBondContact O-CG2 3.31Å; T127-V131 PolarHBondContact O-N 3.49Å; T127-V217 HydrophobicContact CG2-CB 3.95Å; T127-V217 HydrophobicContact CG2-CG1 3.54Å; T127-I218 HydrophobicContact CG2-CG1 4.38Å
128	C	94.8	Very high	92.8	Very high	31 Å²	31	17.7 Å²	17.7	21%	0.209	9%	0.087	C	C	.	.	H	α-helix	trans	-63.9	-37.1	176.9	-74	0	0	0	0	112.8	Y73 Y124 F125 S130 V131 D132 I159	Y73-C128 HydrophobicContact CD2-CB 4.47Å; Y73-C128 HydrophobicContact CE2-CB 4.14Å; Y124-C128 PolarHBondContact O-N 2.93Å; Y124-C128 PolarHBondContact O-SG 3.34Å; F125-C128 PolarHBondContact O-N 3.22Å; C128-S130 VanDerWaalsContact C-N 3.32Å; C128-S130 PolarHBondContact O-N 2.91Å; C128-V131 PolarHBondContact O-N 2.92Å; C128-D132 VanDerWaalsContact O-CB 3.3Å; C128-D132 WeakPolarHBondContact O-CB 3.33Å; C128-D132 PolarHBondContact O-N 2.92Å; C128-I159 HydrophobicContact CB-CD1 4.34Å
129	M	92	Very high	92.2	Very high	5 Å²	5	22.5 Å²	22.5	3%	0.025	11%	0.106	C	C	.	.	H	α-helix	trans	-60.9	-41.7	171.8	-73.9	-170.4	-66	0	0	111.6	Y73 I74 L77 F125 I126 T127 D132 R133 V250 V253	Y73-M129 HydrophobicContact CD2-CG 3.98Å; Y73-M129 HydrophobicContact CG-CG 4.23Å; I74-M129 HydrophobicContact CG1-SD 4.02Å; L77-M129 HydrophobicContact CD2-CE 3.6Å; F125-M129 VanDerWaalsContact O-CG 3.32Å; F125-M129 WeakPolarHBondContact O-CG 3.5Å; F125-M129 PolarHBondContact O-N 3.35Å; I126-M129 HydrophobicContact CB-CE 4.27Å; I126-M129 HydrophobicContact CG1-CE 3.8Å; I126-M129 PolarHBondContact O-N 3.46Å; T127-M129 VanDerWaalsContact C-N 3.34Å; T127-M129 PolarHBondContact O-N 3.01Å; M129-D132 PolarHBondContact O-N 3.42Å; M129-R133 WeakPolarHBondContact O-CG 3.47Å; M129-R133 PolarHBondContact O-N 2.92Å; M129-V250 HydrophobicContact CB-CG1 4.01Å; M129-V250 HydrophobicContact CB-CG2 4.44Å; M129-V253 HydrophobicContact CE-CG1 4.34Å
130	S	92.9	Very high	91.3	Very high	0 Å²	0	25 Å²	25	0%	0	12%	0.122	C	C	.	.	H	α-helix	trans	-65.2	-42.7	177.8	-56.4	0	0	0	0	112	I126 T127 C128 R133 Y134	I126-S130 PolarHBondContact O-N 2.97Å; I126-S130 PolarHBondContact O-OG 3.34Å; T127-S130 WeakPolarHBondContact O-CB 3.32Å; T127-S130 PolarHBondContact O-N 3.26Å; T127-S130 VanDerWaalsContact O-N 3.13Å; C128-S130 VanDerWaalsContact C-N 3.32Å; C128-S130 PolarHBondContact O-N 2.91Å; S130-R133 PolarHBondContact O-N 3.15Å; S130-Y134 PolarHBondContact O-N 2.82Å
131	V	93.1	Very high	90.1	Very high	41 Å²	41	30.5 Å²	30.5	25%	0.248	15%	0.152	C	C	.	.	H	α-helix	trans	-65.4	-40.9	174.9	174.2	0	0	0	0	111.6	T127 C128 R133 Y134 R135 V217	T127-V131 WeakPolarHBondContact O-CG2 3.31Å; T127-V131 PolarHBondContact O-N 3.49Å; C128-V131 PolarHBondContact O-N 2.92Å; V131-R133 VanDerWaalsContact C-N 3.3Å; V131-R133 PolarHBondContact O-N 2.94Å; V131-Y134 PolarHBondContact O-N 2.82Å; V131-R135 WeakPolarHBondContact O-CG 3.46Å; V131-R135 PolarHBondContact O-N 2.77Å; V131-V217 HydrophobicContact CG2-CG1 3.99Å
132	D	88.8	Confident	88.7	Confident	13 Å²	13	37.1 Å²	37.1	7%	0.07	18%	0.182	C	C	.	.	H	α-helix	trans	-59.8	-40.9	175.1	176.2	74	0	0	0	111.6	V69 Y73 C128 M129 A136 R147	V69-D132 WeakPolarHBondContact CG1-OD1 3.42Å; Y73-D132 HydrophobicContact CE2-CB 4.35Å; C128-D132 VanDerWaalsContact O-CB 3.3Å; C128-D132 WeakPolarHBondContact O-CB 3.33Å; C128-D132 PolarHBondContact O-N 2.92Å; M129-D132 PolarHBondContact O-N 3.42Å; D132-A136 WeakPolarHBondContact O-CB 3.49Å; D132-A136 PolarHBondContact O-N 3.45Å; D132-A136 VanDerWaalsContact O-N 3.07Å; D132-R147 PolarHBondContact O-NH1 3.27Å; D132-R147 IonicContact OD1-CZ 3.92Å; D132-R147 IonicContact OD1-NH1 3.59Å; D132-R147 PolarHBondContact OD1-NH1 3.3Å; D132-R147 IonicContact OD1-NH2 3.58Å; D132-R147 IonicContact OD2-CZ 2.83Å; D132-R147 IonicContact OD2-NH1 3.38Å; D132-R147 PolarHBondContact OD2-NH1 2.93Å; D132-R147 IonicContact OD2-NH2 3.93Å
133	R	88.6	Confident	87.3	Confident	10 Å²	10	37.7 Å²	37.7	4%	0.038	19%	0.186	C	C	.	.	H	α-helix	trans	-66.1	-47.5	174.5	-71	-53.4	91.9	173.9	12.9	112.6	M129 S130 V131 R135 A136 I137 L243 V246 V250	M129-R133 WeakPolarHBondContact O-CG 3.47Å; M129-R133 PolarHBondContact O-N 2.92Å; S130-R133 PolarHBondContact O-N 3.15Å; V131-R133 VanDerWaalsContact C-N 3.3Å; V131-R133 PolarHBondContact O-N 2.94Å; R133-R135 VanDerWaalsContact C-N 3.32Å; R133-R135 PolarHBondContact O-N 3.17Å; R133-A136 PolarHBondContact O-N 3.14Å; R133-I137 WeakPolarHBondContact O-CG1 3.36Å; R133-I137 PolarHBondContact O-N 2.8Å; R133-I137 VanDerWaalsContact O-N 3.08Å; R133-L243 VanDerWaalsContact NH1-CD1 3.32Å; R133-V246 VanDerWaalsContact NH1-CG1 3.34Å; R133-V250 HydrophobicContact CG-CB 4.18Å; R133-V250 HydrophobicContact CG-CG1 4.36Å; R133-V250 HydrophobicContact CG-CG2 3.85Å
134	Y	89.6	Confident	85.9	Confident	27 Å²	27	45.1 Å²	45.1	11%	0.106	22%	0.221	C	C	.	.	H	α-helix	trans	-54.5	-49.3	176.6	165.5	-110	0	0	0	111.5	S130 V131 A136 I137 V138 Y139 C221 R224 I225	S130-Y134 PolarHBondContact O-N 2.82Å; V131-Y134 PolarHBondContact O-N 2.82Å; Y134-A136 PolarHBondContact O-N 3.3Å; Y134-I137 PolarHBondContact O-N 3.24Å; Y134-V138 HydrophobicContact CD2-CB 4.21Å; Y134-V138 HydrophobicContact CD2-CG2 3.65Å; Y134-V138 HydrophobicContact CE2-CB 3.95Å; Y134-V138 HydrophobicContact CE2-CG1 4.1Å; Y134-V138 HydrophobicContact CE2-CG2 3.62Å; Y134-V138 WeakPolarHBondContact O-CB 3.38Å; Y134-V138 WeakPolarHBondContact O-CG2 3.14Å; Y134-V138 PolarHBondContact O-N 2.91Å; Y134-Y139 HydrophobicContact CE1-CE2 4.09Å; Y134-Y139 AromaticContact CZ-CE2 3.86Å; Y134-C221 HydrophobicContact CG-CB 4.48Å; Y134-R224 HydrophobicContact CD2-CB 4.05Å; Y134-R224 HydrophobicContact CE2-CB 3.54Å; Y134-R224 HydrophobicContact CE2-CG 4.32Å; Y134-R224 PolarHBondContact OH-NH1 3.49Å; Y134-I225 HydrophobicContact CD2-CG1 4.11Å
135	R	87.9	Confident	84	Confident	117 Å²	117	49.1 Å²	49.1	44%	0.442	25%	0.253	S	S	.	.	H	α-helix	trans	-63.7	-39.8	179.1	-72.7	-178.7	171.7	-172.6	-1.8	112.9	V131 R133 I137 Y139 S143	V131-R135 WeakPolarHBondContact O-CG 3.46Å; V131-R135 PolarHBondContact O-N 2.77Å; R133-R135 VanDerWaalsContact C-N 3.32Å; R133-R135 PolarHBondContact O-N 3.17Å; R135-I137 VanDerWaalsContact C-N 3.33Å; R135-I137 PolarHBondContact O-N 3.03Å; R135-Y139 CarbonylContact O-C 3.59Å; R135-Y139 WeakPolarHBondContact O-CA 3.39Å; R135-Y139 PolarHBondContact O-N 3.49Å; R135-Y139 VanDerWaalsContact O-N 3.08Å; R135-S143 WeakPolarHBondContact O-CB 3.49Å
136	A	84.1	Confident	82.2	Confident	12 Å²	12	50.9 Å²	50.9	10%	0.099	27%	0.265	C	S	.	.	H	α-helix	trans	-65.6	-34.7	179.9	0	0	0	0	0	113.4	D132 R133 Y134 L243	D132-A136 WeakPolarHBondContact O-CB 3.49Å; D132-A136 PolarHBondContact O-N 3.45Å; D132-A136 VanDerWaalsContact O-N 3.07Å; R133-A136 PolarHBondContact O-N 3.14Å; Y134-A136 PolarHBondContact O-N 3.3Å; A136-L243 HydrophobicContact CB-CD1 4.46Å
137	I	84	Confident	81	Confident	20 Å²	20	54.6 Å²	54.6	10%	0.103	28%	0.279	C	S	.	.	H	α-helix	trans	-88.1	-45.3	-175.6	-64.6	167.6	0	0	0	111.2	R133 Y134 R135 I225 L229 L243 M247	R133-I137 WeakPolarHBondContact O-CG1 3.36Å; R133-I137 PolarHBondContact O-N 2.8Å; R133-I137 VanDerWaalsContact O-N 3.08Å; Y134-I137 PolarHBondContact O-N 3.24Å; R135-I137 VanDerWaalsContact C-N 3.33Å; R135-I137 PolarHBondContact O-N 3.03Å; I137-I225 HydrophobicContact CD1-CD1 4.32Å; I137-I225 HydrophobicContact CD1-CG1 4.47Å; I137-I225 HydrophobicContact CD1-CG2 4.02Å; I137-I225 HydrophobicContact CG2-CG2 4.33Å; I137-L229 HydrophobicContact CG2-CD2 4.4Å; I137-L243 HydrophobicContact CG1-CD1 4.45Å; I137-L243 HydrophobicContact CG1-CD2 4.21Å; I137-L243 HydrophobicContact CG1-CG 4.45Å; I137-M247 HydrophobicContact CD1-CG 4.33Å; I137-M247 HydrophobicContact CD1-SD 3.88Å
138	V	85	Confident	80.3	Confident	22 Å²	22	57.7 Å²	57.7	13%	0.133	30%	0.295	C	S	.	.	H	α-helix	trans	-86.1	-26.8	-172.7	-179.5	0	0	0	0	112.3	Y134 I225 H228	Y134-V138 HydrophobicContact CD2-CB 4.21Å; Y134-V138 HydrophobicContact CD2-CG2 3.65Å; Y134-V138 HydrophobicContact CE2-CB 3.95Å; Y134-V138 HydrophobicContact CE2-CG1 4.1Å; Y134-V138 HydrophobicContact CE2-CG2 3.62Å; Y134-V138 WeakPolarHBondContact O-CB 3.38Å; Y134-V138 WeakPolarHBondContact O-CG2 3.14Å; Y134-V138 PolarHBondContact O-N 2.91Å; V138-I225 HydrophobicContact CG2-CG1 4.49Å; V138-H228 HydrophobicContact CG2-CB 4.02Å
139	Y	83.3	Confident	79.8	Confident	102 Å²	102	58.7 Å²	58.7	40%	0.4	30%	0.298	S	S	.	.			trans	-132.9	59.8	-178.7	-55.3	-74	0	0	0	112.4	Y134 R135 L141 Q142 S143	Y134-Y139 HydrophobicContact CE1-CE2 4.09Å; Y134-Y139 AromaticContact CZ-CE2 3.86Å; R135-Y139 CarbonylContact O-C 3.59Å; R135-Y139 WeakPolarHBondContact O-CA 3.39Å; R135-Y139 PolarHBondContact O-N 3.49Å; R135-Y139 VanDerWaalsContact O-N 3.08Å; Y139-L141 PolarHBondContact O-N 3.3Å; Y139-Q142 PolarHBondContact O-N 2.7Å; Y139-S143 WeakPolarHBondContact O-CB 3.02Å; Y139-S143 PolarHBondContact O-N 3.08Å; Y139-S143 PolarHBondContact O-OG 3.18Å
140	P	77.6	Confident	79.6	Confident	62 Å²	62	62 Å²	62	40%	0.403	32%	0.321	S	S	.	.	H	α-helix	trans	-56	-47.9	-169.8	20.7	-32.5	0	0	0	113.3	S143 Q144	P140-S143 PolarHBondContact O-N 2.92Å; P140-S143 PolarHBondContact O-OG 3.35Å; P140-Q144 PolarHBondContact O-N 3.41Å
141	L	72.3	Confident	79.4	Confident	126 Å²	126	67.3 Å²	67.3	66%	0.66	34%	0.341	S	S	*	.	H	α-helix	trans	-64.6	-44	-178.5	-62.4	174.8	0	0	0	112.9	Y139 S143	Y139-L141 PolarHBondContact O-N 3.3Å; L141-S143 VanDerWaalsContact C-N 3.34Å
142	Q	68.6	Low	79.3	Confident	138 Å²	138	65.4 Å²	65.4	65%	0.645	33%	0.33	S	S	*	.	H	α-helix	trans	-70.2	-33.9	175.8	-64.3	176.5	1.7	0	0	111.5	Y139 Q144 C145 S146	Y139-Q142 PolarHBondContact O-N 2.7Å; Q142-Q144 VanDerWaalsContact C-N 3.32Å; Q142-Q144 PolarHBondContact O-N 2.84Å; Q142-C145 PolarHBondContact O-N 2.69Å; Q142-S146 WeakPolarHBondContact O-CB 3.38Å; Q142-S146 PolarHBondContact O-N 3.13Å; Q142-S146 VanDerWaalsContact O-N 3.11Å
143	S	68	Low	79.5	Confident	12 Å²	12	72.6 Å²	72.6	8%	0.084	36%	0.356	C	S	.	.	H	α-helix	trans	-67.5	-33.4	179.8	85.4	0	0	0	0	112.2	R135 Y139 P140 L141 C145 S146 R147	R135-S143 WeakPolarHBondContact O-CB 3.49Å; Y139-S143 WeakPolarHBondContact O-CB 3.02Å; Y139-S143 PolarHBondContact O-N 3.08Å; Y139-S143 PolarHBondContact O-OG 3.18Å; P140-S143 PolarHBondContact O-N 2.92Å; P140-S143 PolarHBondContact O-OG 3.35Å; L141-S143 VanDerWaalsContact C-N 3.34Å; S143-C145 VanDerWaalsContact C-N 3.33Å; S143-C145 PolarHBondContact O-N 2.81Å; S143-S146 PolarHBondContact O-N 3.11Å; S143-S146 VanDerWaalsContact O-N 3.13Å; S143-R147 VanDerWaalsContact O-CB 3.26Å; S143-R147 WeakPolarHBondContact O-CB 3.29Å; S143-R147 WeakPolarHBondContact O-CD 3.33Å; S143-R147 WeakPolarHBondContact O-CG 3.36Å; S143-R147 PolarHBondContact O-N 3.48Å
144	Q	67.8	Low	79.8	Confident	156 Å²	156	76.4 Å²	76.4	73%	0.729	38%	0.38	S	S	*	.	H	α-helix	trans	-63.7	-38.8	-179.9	-169.1	163.3	-9	0	0	111.9	P140 Q142	P140-Q144 PolarHBondContact O-N 3.41Å; Q142-Q144 VanDerWaalsContact C-N 3.32Å; Q142-Q144 PolarHBondContact O-N 2.84Å
145	C	58.3	Low	80.1	Confident	120 Å²	120	78 Å²	78	81%	0.811	39%	0.39	S	S	*	.	H	α-helix	trans	-77.3	-27.7	173	-62	0	0	0	0	113.1	Q142 S143	Q142-C145 PolarHBondContact O-N 2.69Å; S143-C145 VanDerWaalsContact C-N 3.33Å; S143-C145 PolarHBondContact O-N 2.81Å
146	S	59.4	Low	80.6	Confident	36 Å²	36	72.6 Å²	72.6	25%	0.252	37%	0.37	S	S	.	.	H	α-helix	trans	-86.9	-30.4	-173.6	-173.4	0	0	0	0	113.4	Q142 S143 N148 R151	Q142-S146 WeakPolarHBondContact O-CB 3.38Å; Q142-S146 PolarHBondContact O-N 3.13Å; Q142-S146 VanDerWaalsContact O-N 3.11Å; S143-S146 PolarHBondContact O-N 3.11Å; S143-S146 VanDerWaalsContact O-N 3.13Å; S146-N148 PolarHBondContact O-N 2.9Å; S146-R151 PolarHBondContact O-NH1 3.44Å; S146-R151 PolarHBondContact OG-NH1 3.5Å
147	R	68.1	Low	81.2	Confident	78 Å²	78	73.8 Å²	73.8	29%	0.294	38%	0.383	S	S	.	.			trans	-76.6	67.9	-177	-73.5	167.6	67.2	98.1	7.4	112.1	V69 D132 S143	V69-R147 HydrophobicContact CG2-CB 4.1Å; D132-R147 PolarHBondContact O-NH1 3.27Å; D132-R147 IonicContact OD1-CZ 3.92Å; D132-R147 IonicContact OD1-NH1 3.59Å; D132-R147 PolarHBondContact OD1-NH1 3.3Å; D132-R147 IonicContact OD1-NH2 3.58Å; D132-R147 IonicContact OD2-CZ 2.83Å; D132-R147 IonicContact OD2-NH1 3.38Å; D132-R147 PolarHBondContact OD2-NH1 2.93Å; D132-R147 IonicContact OD2-NH2 3.93Å; S143-R147 VanDerWaalsContact O-CB 3.26Å; S143-R147 WeakPolarHBondContact O-CB 3.29Å; S143-R147 WeakPolarHBondContact O-CD 3.33Å; S143-R147 WeakPolarHBondContact O-CG 3.36Å; S143-R147 PolarHBondContact O-N 3.48Å
148	N	81.6	Confident	81.9	Confident	84 Å²	84	76.3 Å²	76.3	45%	0.449	40%	0.399	S	S	.	.			trans	-92.4	133.2	175.6	-175.2	-15.9	0	0	0	111.1	S146 C150 R151 A152	S146-N148 PolarHBondContact O-N 2.9Å; N148-C150 VanDerWaalsContact C-N 3.27Å; N148-C150 PolarHBondContact O-N 3.41Å; N148-C150 WeakPolarHBondContact OD1-CB 3.31Å; N148-C150 PolarHBondContact OD1-N 3Å; N148-R151 HydrophobicContact CB-CB 4.39Å; N148-R151 HydrophobicContact CB-CG 4.17Å; N148-R151 PolarHBondContact O-N 3.17Å; N148-A152 PolarHBondContact O-N 2.87Å; N148-A152 VanDerWaalsContact O-N 3.08Å
149	L	84.6	Confident	82.6	Confident	52 Å²	52	75.8 Å²	75.8	27%	0.272	40%	0.395	S	S	.	.	H	α-helix	trans	-59.3	-35	175	-68.7	174.7	0	0	0	113	K67 A152 R153	K67-L149 HydrophobicContact CB-CD1 3.81Å; K67-L149 HydrophobicContact CB-CD2 4.27Å; L149-A152 PolarHBondContact O-N 3.17Å; L149-R153 WeakPolarHBondContact O-CG 3.48Å; L149-R153 PolarHBondContact O-N 3.28Å
150	C	88.2	Confident	83.3	Confident	74 Å²	74	73.8 Å²	73.8	50%	0.5	39%	0.387	S	S	.	.	H	α-helix	trans	-60.7	-46.9	175.6	-175.6	0	0	0	0	110.6	N148 A152 R153 V154	N148-C150 VanDerWaalsContact C-N 3.27Å; N148-C150 PolarHBondContact O-N 3.41Å; N148-C150 WeakPolarHBondContact OD1-CB 3.31Å; N148-C150 PolarHBondContact OD1-N 3Å; C150-A152 VanDerWaalsContact C-N 3.34Å; C150-A152 PolarHBondContact O-N 3.3Å; C150-R153 WeakPolarHBondContact O-CB 3.37Å; C150-R153 PolarHBondContact O-N 2.99Å; C150-R153 VanDerWaalsContact O-N 3.17Å; C150-V154 WeakPolarHBondContact O-CG2 3.5Å; C150-V154 PolarHBondContact O-N 3.3Å
151	R	89.4	Confident	84.3	Confident	111 Å²	111	75.7 Å²	75.7	42%	0.419	40%	0.398	S	S	.	.	H	α-helix	trans	-62.1	-41.2	176.1	-68.4	179.9	67.7	-155.8	10.7	112.1	S146 N148 R153 V154 I155	S146-R151 PolarHBondContact O-NH1 3.44Å; S146-R151 PolarHBondContact OG-NH1 3.5Å; N148-R151 HydrophobicContact CB-CB 4.39Å; N148-R151 HydrophobicContact CB-CG 4.17Å; N148-R151 PolarHBondContact O-N 3.17Å; R151-R153 VanDerWaalsContact C-N 3.3Å; R151-R153 PolarHBondContact O-N 3.41Å; R151-V154 PolarHBondContact O-N 3.03Å; R151-I155 WeakPolarHBondContact O-CB 3.43Å; R151-I155 VanDerWaalsContact O-CG1 3.25Å; R151-I155 WeakPolarHBondContact O-CG1 3.45Å; R151-I155 PolarHBondContact O-N 2.98Å
152	A	90.9	Very high	85.5	Confident	2 Å²	2	73 Å²	73	2%	0.017	38%	0.383	C	S	.	.	H	α-helix	trans	-60.6	-39.6	176.1	0	0	0	0	0	112.2	V69 T72 Y73 N148 L149 C150 S156	V69-A152 HydrophobicContact CB-CB 4.35Å; V69-A152 HydrophobicContact CG1-CB 3.92Å; V69-A152 HydrophobicContact CG2-CB 4.18Å; T72-A152 HydrophobicContact CG2-CB 4.24Å; Y73-A152 HydrophobicContact CE1-CB 4.29Å; N148-A152 PolarHBondContact O-N 2.87Å; N148-A152 VanDerWaalsContact O-N 3.08Å; L149-A152 PolarHBondContact O-N 3.17Å; C150-A152 VanDerWaalsContact C-N 3.34Å; C150-A152 PolarHBondContact O-N 3.3Å; A152-S156 WeakPolarHBondContact O-CB 3.4Å; A152-S156 PolarHBondContact O-N 3.01Å; A152-S156 PolarHBondContact O-OG 3.14Å
153	R	92.8	Very high	86.9	Confident	164 Å²	164	66.4 Å²	66.4	62%	0.619	35%	0.353	S	S	*	.	H	α-helix	trans	-67.1	-44.1	174.8	-70.6	175.8	-176.7	157	0.1	112.4	L149 C150 R151 S156 G157	L149-R153 WeakPolarHBondContact O-CG 3.48Å; L149-R153 PolarHBondContact O-N 3.28Å; C150-R153 WeakPolarHBondContact O-CB 3.37Å; C150-R153 PolarHBondContact O-N 2.99Å; C150-R153 VanDerWaalsContact O-N 3.17Å; R151-R153 VanDerWaalsContact C-N 3.3Å; R151-R153 PolarHBondContact O-N 3.41Å; R153-S156 WeakPolarHBondContact O-CB 3.26Å; R153-S156 PolarHBondContact O-N 2.93Å; R153-G157 PolarHBondContact O-N 2.92Å
154	V	95.5	Very high	88.4	Confident	90 Å²	90	67.3 Å²	67.3	55%	0.545	36%	0.364	S	S	.	.	H	α-helix	trans	-59.4	-48.4	175	172.3	0	0	0	0	110.5	C150 R151 S156 G157 V158	C150-V154 WeakPolarHBondContact O-CG2 3.5Å; C150-V154 PolarHBondContact O-N 3.3Å; R151-V154 PolarHBondContact O-N 3.03Å; V154-S156 VanDerWaalsContact C-N 3.28Å; V154-S156 PolarHBondContact O-N 3.22Å; V154-G157 PolarHBondContact O-N 3.36Å; V154-G157 VanDerWaalsContact O-N 3.14Å; V154-V158 WeakPolarHBondContact O-CG2 3.17Å; V154-V158 PolarHBondContact O-N 3.18Å
155	I	95.8	Very high	89.8	Confident	60 Å²	60	64.8 Å²	64.8	31%	0.308	36%	0.355	S	S	.	.	H	α-helix	trans	-58.2	-42	175.7	-69.6	165.4	0	0	0	110.8	Y73 R151 G157 V158 I159	Y73-I155 HydrophobicContact CE1-CG2 4.15Å; R151-I155 WeakPolarHBondContact O-CB 3.43Å; R151-I155 VanDerWaalsContact O-CG1 3.25Å; R151-I155 WeakPolarHBondContact O-CG1 3.45Å; R151-I155 PolarHBondContact O-N 2.98Å; I155-G157 PolarHBondContact O-N 3.34Å; I155-V158 PolarHBondContact O-N 3.23Å; I155-I159 HydrophobicContact CG2-CD1 3.89Å; I155-I159 HydrophobicContact CG2-CG1 4.42Å; I155-I159 VanDerWaalsContact O-CG1 3.31Å; I155-I159 WeakPolarHBondContact O-CG1 3.2Å; I155-I159 PolarHBondContact O-N 3.46Å
156	S	97.2	Very high	91.6	Very high	4 Å²	4	61.4 Å²	61.4	3%	0.028	33%	0.328	C	S	.	.	H	α-helix	trans	-62	-43.6	177	-54.3	0	0	0	0	111.5	N76 A152 R153 V154 V158 I159 W160	N76-S156 PolarHBondContact ND2-OG 3.32Å; A152-S156 WeakPolarHBondContact O-CB 3.4Å; A152-S156 PolarHBondContact O-N 3.01Å; A152-S156 PolarHBondContact O-OG 3.14Å; R153-S156 WeakPolarHBondContact O-CB 3.26Å; R153-S156 PolarHBondContact O-N 2.93Å; V154-S156 VanDerWaalsContact C-N 3.28Å; V154-S156 PolarHBondContact O-N 3.22Å; S156-V158 PolarHBondContact O-N 2.82Å; S156-I159 PolarHBondContact O-N 3.03Å; S156-W160 PolarHBondContact O-N 2.91Å
157	G	97.9	Very high	93.4	Very high	36 Å²	36	60 Å²	60	37%	0.371	32%	0.318	S	S	.	.	H	α-helix	trans	-59.7	-43.8	174	0	0	0	0	0	112.5	R153 V154 I155 I159 W160 T161	R153-G157 PolarHBondContact O-N 2.92Å; V154-G157 PolarHBondContact O-N 3.36Å; V154-G157 VanDerWaalsContact O-N 3.14Å; I155-G157 PolarHBondContact O-N 3.34Å; G157-I159 PolarHBondContact O-N 3.28Å; G157-W160 PolarHBondContact O-N 3.45Å; G157-T161 PolarHBondContact O-N 3.39Å; G157-T161 PolarHBondContact O-OG1 3.16Å; G157-T161 VanDerWaalsContact O-OG1 3.05Å
158	V	98.3	Very high	94.8	Very high	74 Å²	74	60.9 Å²	60.9	45%	0.448	33%	0.327	S	S	.	.	H	α-helix	trans	-60.9	-43.6	175.3	172.2	0	0	0	0	111.4	V154 I155 S156 W160 T161 I162	V154-V158 WeakPolarHBondContact O-CG2 3.17Å; V154-V158 PolarHBondContact O-N 3.18Å; I155-V158 PolarHBondContact O-N 3.23Å; S156-V158 PolarHBondContact O-N 2.82Å; V158-W160 PolarHBondContact O-N 3.44Å; V158-T161 PolarHBondContact O-N 3.29Å; V158-I162 HydrophobicContact CG1-CD1 3.65Å; V158-I162 HydrophobicContact CG1-CG1 4.28Å; V158-I162 VanDerWaalsContact O-CG1 3.31Å; V158-I162 WeakPolarHBondContact O-CG1 3.41Å; V158-I162 PolarHBondContact O-N 2.91Å
159	I	98.4	Very high	95.4	Very high	10 Å²	10	58.8 Å²	58.8	5%	0.051	32%	0.318	C	S	.	.	H	α-helix	trans	-59.7	-46.8	176.8	-70.6	165.6	0	0	0	110.8	Y124 F125 C128 I155 S156 G157 T161 I162 A163	Y124-I159 HydrophobicContact CD2-CG2 4.42Å; F125-I159 HydrophobicContact CD1-CD1 3.63Å; F125-I159 HydrophobicContact CD2-CG2 4.01Å; F125-I159 HydrophobicContact CE1-CB 4.26Å; F125-I159 HydrophobicContact CE1-CD1 3.55Å; F125-I159 HydrophobicContact CE1-CG2 4.18Å; F125-I159 HydrophobicContact CE2-CB 4.42Å; F125-I159 HydrophobicContact CE2-CG2 3.6Å; F125-I159 HydrophobicContact CG-CD1 4.3Å; F125-I159 HydrophobicContact CG-CG2 4.41Å; F125-I159 HydrophobicContact CZ-CB 3.97Å; F125-I159 HydrophobicContact CZ-CD1 4.14Å; F125-I159 HydrophobicContact CZ-CG2 3.67Å; C128-I159 HydrophobicContact CB-CD1 4.34Å; I155-I159 HydrophobicContact CG2-CD1 3.89Å; I155-I159 HydrophobicContact CG2-CG1 4.42Å; I155-I159 VanDerWaalsContact O-CG1 3.31Å; I155-I159 WeakPolarHBondContact O-CG1 3.2Å; I155-I159 PolarHBondContact O-N 3.46Å; S156-I159 PolarHBondContact O-N 3.03Å; G157-I159 PolarHBondContact O-N 3.28Å; I159-T161 VanDerWaalsContact C-N 3.33Å; I159-T161 PolarHBondContact O-N 2.99Å; I159-I162 PolarHBondContact O-N 3.09Å; I159-A163 VanDerWaalsContact O-CB 3.28Å; I159-A163 WeakPolarHBondContact O-CB 3.41Å; I159-A163 PolarHBondContact O-N 3.46Å
160	W	98.6	Very high	95.8	Very high	61 Å²	61	57.1 Å²	57.1	23%	0.231	31%	0.31	C	S	.	.	H	α-helix	trans	-59.9	-43.7	177.2	-77.5	116.3	0	0	0	112.1	N76 L79 L83 L117 A121 F125 S156 G157 V158 A163 G164	N76-W160 PolarHBondContact OD1-NE1 3.42Å; L79-W160 HydrophobicContact CB-CZ2 4.41Å; L83-W160 HydrophobicContact CD1-CH2 3.93Å; L83-W160 HydrophobicContact CD1-CZ3 4.17Å; L117-W160 HydrophobicContact CD1-CE3 4.31Å; L117-W160 HydrophobicContact CD1-CZ3 4.38Å; L117-W160 HydrophobicContact CD2-CE3 4.43Å; L117-W160 HydrophobicContact CD2-CZ3 3.9Å; L117-W160 HydrophobicContact CG-CE3 4.49Å; L117-W160 HydrophobicContact CG-CZ3 4.07Å; A121-W160 HydrophobicContact CB-CE3 4.47Å; A121-W160 HydrophobicContact CB-CZ3 4.18Å; F125-W160 HydrophobicContact CE2-CZ2 4.31Å; F125-W160 AromaticContact CZ-NE1 3.82Å; S156-W160 PolarHBondContact O-N 2.91Å; G157-W160 PolarHBondContact O-N 3.45Å; V158-W160 PolarHBondContact O-N 3.44Å; W160-A163 PolarHBondContact O-N 2.98Å; W160-G164 PolarHBondContact O-N 2.74Å
161	T	98.4	Very high	96.2	Very high	102 Å²	102	58.5 Å²	58.5	63%	0.626	31%	0.311	S	S	*	.	H	α-helix	trans	-62.3	-47.2	176.9	-57.5	0	0	0	0	111.7	G157 V158 I159 G164 L165	G157-T161 PolarHBondContact O-N 3.39Å; G157-T161 PolarHBondContact O-OG1 3.16Å; G157-T161 VanDerWaalsContact O-OG1 3.05Å; V158-T161 PolarHBondContact O-N 3.29Å; I159-T161 VanDerWaalsContact C-N 3.33Å; I159-T161 PolarHBondContact O-N 2.99Å; T161-G164 PolarHBondContact O-N 3.4Å; T161-L165 WeakPolarHBondContact O-CB 3.4Å; T161-L165 PolarHBondContact O-N 3.38Å
162	I	98.2	Very high	96.4	Very high	68 Å²	68	56.5 Å²	56.5	35%	0.349	32%	0.317	S	S	.	.	H	α-helix	trans	-64.9	-45.4	179.3	-65.3	170.4	0	0	0	110.4	Y124 V158 I159 G164 L165 M166	Y124-I162 HydrophobicContact CD2-CG2 4.42Å; Y124-I162 HydrophobicContact CE2-CG2 3.77Å; V158-I162 HydrophobicContact CG1-CD1 3.65Å; V158-I162 HydrophobicContact CG1-CG1 4.28Å; V158-I162 VanDerWaalsContact O-CG1 3.31Å; V158-I162 WeakPolarHBondContact O-CG1 3.41Å; V158-I162 PolarHBondContact O-N 2.91Å; I159-I162 PolarHBondContact O-N 3.09Å; I162-G164 VanDerWaalsContact C-N 3.3Å; I162-G164 PolarHBondContact O-N 2.98Å; I162-L165 WeakPolarHBondContact O-CB 3.48Å; I162-L165 PolarHBondContact O-N 3.26Å; I162-M166 HydrophobicContact CG2-CE 4.29Å; I162-M166 HydrophobicContact CG2-CG 4.39Å; I162-M166 VanDerWaalsContact O-CG 3.31Å; I162-M166 WeakPolarHBondContact O-CG 3.45Å; I162-M166 PolarHBondContact O-N 3.21Å
163	A	98.3	Very high	96.6	Very high	0 Å²	0	58.1 Å²	58.1	0%	0	32%	0.324	C	S	.	.	H	α-helix	trans	-62.2	-38.7	177.7	0	0	0	0	0	111.9	L117 A121 I159 W160 M166 T167	L117-A163 HydrophobicContact CD1-CB 3.79Å; A121-A163 HydrophobicContact CB-CB 4.03Å; I159-A163 VanDerWaalsContact O-CB 3.28Å; I159-A163 WeakPolarHBondContact O-CB 3.41Å; I159-A163 PolarHBondContact O-N 3.46Å; W160-A163 PolarHBondContact O-N 2.98Å; A163-M166 PolarHBondContact O-N 3.26Å; A163-T167 WeakPolarHBondContact O-CB 3.35Å; A163-T167 PolarHBondContact O-N 3Å; A163-T167 VanDerWaalsContact O-N 3.13Å; A163-T167 PolarHBondContact O-OG1 2.94Å
164	G	98.1	Very high	96.7	Very high	31 Å²	31	51.5 Å²	51.5	32%	0.32	30%	0.299	S	S	.	.	H	α-helix	trans	-62.4	-45	172.6	0	0	0	0	0	112.6	W160 T161 I162 M166 T167 I168	W160-G164 PolarHBondContact O-N 2.74Å; T161-G164 PolarHBondContact O-N 3.4Å; I162-G164 VanDerWaalsContact C-N 3.3Å; I162-G164 PolarHBondContact O-N 2.98Å; G164-M166 PolarHBondContact O-N 3.32Å; G164-T167 WeakPolarHBondContact O-CB 3.41Å; G164-T167 PolarHBondContact O-N 3.48Å; G164-T167 VanDerWaalsContact O-N 3.08Å; G164-I168 PolarHBondContact O-N 3.36Å
165	L	97.7	Very high	96.7	Very high	103 Å²	103	49.9 Å²	49.9	54%	0.539	29%	0.287	S	S	.	.	H	α-helix	trans	-60.1	-44.8	175.6	179.9	61.9	0	0	0	111.6	T161 I162 T167 I168	T161-L165 WeakPolarHBondContact O-CB 3.4Å; T161-L165 PolarHBondContact O-N 3.38Å; I162-L165 WeakPolarHBondContact O-CB 3.48Å; I162-L165 PolarHBondContact O-N 3.26Å; L165-T167 PolarHBondContact O-N 3.42Å; L165-I168 HydrophobicContact CD1-CD1 3.57Å; L165-I168 WeakPolarHBondContact O-CB 3.24Å; L165-I168 WeakPolarHBondContact O-CG1 3.47Å; L165-I168 PolarHBondContact O-N 3.25Å; L165-I168 VanDerWaalsContact O-N 3.17Å
166	M	96.5	Very high	96.7	Very high	49 Å²	49	49.3 Å²	49.3	24%	0.241	29%	0.287	C	S	.	.	H	α-helix	trans	-67.4	-17	177.1	-63.2	-57.4	160.2	0	0	113.5	Y120 I162 A163 G164 P169 L209	Y120-M166 HydrophobicContact CD1-CB 4.03Å; Y120-M166 HydrophobicContact CD1-CG 4.28Å; Y120-M166 HydrophobicContact CD2-CB 3.56Å; Y120-M166 HydrophobicContact CE1-CB 3.97Å; Y120-M166 HydrophobicContact CE1-CG 4.28Å; Y120-M166 HydrophobicContact CE2-CB 3.5Å; Y120-M166 HydrophobicContact CG-CB 3.84Å; Y120-M166 HydrophobicContact CG-CG 4.44Å; I162-M166 HydrophobicContact CG2-CE 4.29Å; I162-M166 HydrophobicContact CG2-CG 4.39Å; I162-M166 VanDerWaalsContact O-CG 3.31Å; I162-M166 WeakPolarHBondContact O-CG 3.45Å; I162-M166 PolarHBondContact O-N 3.21Å; A163-M166 PolarHBondContact O-N 3.26Å; G164-M166 PolarHBondContact O-N 3.32Å; M166-P169 WeakPolarHBondContact O-CD 3.31Å; M166-L209 HydrophobicContact CE-CD1 3.75Å; M166-L209 HydrophobicContact SD-CD1 3.5Å; M166-L209 VanDerWaalsContact SD-CD1 3.5Å
167	T	97.1	Very high	96.5	Very high	8 Å²	8	55.4 Å²	55.4	5%	0.049	31%	0.31	C	S	.	.	H	α-helix	trans	-83.4	-16.4	177	-61.5	0	0	0	0	112.7	C113 L117 A163 G164 L165 T170 M171	C113-T167 HydrophobicContact CB-CG2 3.64Å; L117-T167 WeakPolarHBondContact CA-OG1 3.4Å; L117-T167 PolarHBondContact N-OG1 2.93Å; A163-T167 WeakPolarHBondContact O-CB 3.35Å; A163-T167 PolarHBondContact O-N 3Å; A163-T167 VanDerWaalsContact O-N 3.13Å; A163-T167 PolarHBondContact O-OG1 2.94Å; G164-T167 WeakPolarHBondContact O-CB 3.41Å; G164-T167 PolarHBondContact O-N 3.48Å; G164-T167 VanDerWaalsContact O-N 3.08Å; L165-T167 PolarHBondContact O-N 3.42Å; T167-T170 WeakPolarHBondContact O-CA 3.29Å; T167-T170 VanDerWaalsContact O-CB 3.28Å; T167-T170 WeakPolarHBondContact O-CB 3.49Å; T167-T170 PolarHBondContact O-N 2.91Å; T167-M171 PolarHBondContact O-N 3.24Å; T167-M171 VanDerWaalsContact O-N 3.15Å
168	I	96.6	Very high	96.2	Very high	96 Å²	96	58.4 Å²	58.4	49%	0.492	31%	0.314	S	S	.	.	H	α-helix	trans	-53.6	-45.5	-177.1	-70.4	171.4	0	0	0	113.4	G164 L165 T170 M171 A172	G164-I168 PolarHBondContact O-N 3.36Å; L165-I168 HydrophobicContact CD1-CD1 3.57Å; L165-I168 WeakPolarHBondContact O-CB 3.24Å; L165-I168 WeakPolarHBondContact O-CG1 3.47Å; L165-I168 PolarHBondContact O-N 3.25Å; L165-I168 VanDerWaalsContact O-N 3.17Å; I168-T170 PolarHBondContact O-N 3Å; I168-M171 WeakPolarHBondContact O-CB 3.38Å; I168-M171 PolarHBondContact O-N 2.64Å; I168-A172 PolarHBondContact O-N 3.46Å
169	P	94.3	Very high	95.8	Very high	39 Å²	39	55.4 Å²	55.4	25%	0.253	30%	0.296	S	S	.	.	H	α-helix	trans	-60.4	-32.3	177.2	-24.7	35	0	0	0	112.9	M166 A172 F173 L202	M166-P169 WeakPolarHBondContact O-CD 3.31Å; P169-A172 PolarHBondContact O-N 2.83Å; P169-F173 HydrophobicContact CB-CD2 4.26Å; P169-F173 HydrophobicContact CB-CE2 4.46Å; P169-F173 WeakPolarHBondContact O-CB 3.36Å; P169-F173 WeakPolarHBondContact O-CD2 3.47Å; P169-F173 PolarHBondContact O-N 3.44Å; P169-L202 HydrophobicContact CB-CD1 4.05Å; P169-L202 HydrophobicContact CB-CD2 3.62Å; P169-L202 HydrophobicContact CG-CD2 3.81Å
170	T	94.1	Very high	95.2	Very high	17 Å²	17	64 Å²	64	10%	0.104	33%	0.333	C	S	.	.	H	α-helix	trans	-67.4	-42.9	175.1	-53.3	0	0	0	0	110.6	S116 T167 I168 A172 R174	S116-T170 PolarHBondContact OG-OG1 3.35Å; S116-T170 VanDerWaalsContact OG-OG1 3.07Å; T167-T170 WeakPolarHBondContact O-CA 3.29Å; T167-T170 VanDerWaalsContact O-CB 3.28Å; T167-T170 WeakPolarHBondContact O-CB 3.49Å; T167-T170 PolarHBondContact O-N 2.91Å; I168-T170 PolarHBondContact O-N 3Å; T170-A172 VanDerWaalsContact C-N 3.32Å; T170-A172 PolarHBondContact O-N 2.92Å; T170-R174 HydrophobicContact CG2-CB 4.39Å; T170-R174 WeakPolarHBondContact O-CB 3.36Å; T170-R174 PolarHBondContact O-N 3.21Å
171	M	95.5	Very high	94.6	Very high	104 Å²	104	67.6 Å²	67.6	51%	0.512	35%	0.352	S	S	.	.	H	α-helix	trans	-61.2	-41.5	175.9	-168.4	84	72.5	0	0	112	C113 T167 I168	C113-M171 HydrophobicContact CB-CE 4.41Å; T167-M171 PolarHBondContact O-N 3.24Å; T167-M171 VanDerWaalsContact O-N 3.15Å; I168-M171 WeakPolarHBondContact O-CB 3.38Å; I168-M171 PolarHBondContact O-N 2.64Å
172	A	95	Very high	93.9	Very high	68 Å²	68	68 Å²	68	56%	0.562	35%	0.35	S	S	*	.	H	α-helix	trans	-73.1	-43.6	-175.5	0	0	0	0	0	112.9	I168 P169 T170	I168-A172 PolarHBondContact O-N 3.46Å; P169-A172 PolarHBondContact O-N 2.83Å; T170-A172 VanDerWaalsContact C-N 3.32Å; T170-A172 PolarHBondContact O-N 2.92Å
173	F	94.6	Very high	93.4	Very high	36 Å²	36	67.3 Å²	67.3	16%	0.158	36%	0.359	C	S	.	.	H	α-helix	trans	-100.2	-14.8	-171.8	-64	-62.1	0	0	0	114.6	P169 L189 T190 Y191 P192 W198 L202	P169-F173 HydrophobicContact CB-CD2 4.26Å; P169-F173 HydrophobicContact CB-CE2 4.46Å; P169-F173 WeakPolarHBondContact O-CB 3.36Å; P169-F173 WeakPolarHBondContact O-CD2 3.47Å; P169-F173 PolarHBondContact O-N 3.44Å; F173-L189 HydrophobicContact CB-CD2 4.09Å; F173-T190 PolarHBondContact O-N 2.94Å; F173-Y191 HydrophobicContact CB-CD1 4.26Å; F173-Y191 HydrophobicContact CB-CE1 4.09Å; F173-Y191 HydrophobicContact CD1-CD1 4.16Å; F173-Y191 HydrophobicContact CD2-CD1 4.31Å; F173-Y191 HydrophobicContact CD2-CE1 4.14Å; F173-Y191 AromaticContact CG-CD1 3.99Å; F173-Y191 HydrophobicContact CG-CD1 3.99Å; F173-Y191 HydrophobicContact CG-CE1 4.07Å; F173-P192 HydrophobicContact CE1-CG 4.47Å; F173-W198 HydrophobicContact CE1-CD2 4.46Å; F173-W198 HydrophobicContact CE2-CD2 4.2Å; F173-W198 AromaticContact CE2-CE3 3.67Å; F173-W198 HydrophobicContact CE2-CE3 3.67Å; F173-W198 HydrophobicContact CE2-CH2 4.44Å; F173-W198 AromaticContact CE2-CZ3 3.8Å; F173-W198 HydrophobicContact CE2-CZ3 3.8Å; F173-W198 AromaticContact CZ-CD2 3.71Å; F173-W198 HydrophobicContact CZ-CD2 3.71Å; F173-W198 AromaticContact CZ-CE2 3.93Å; F173-W198 AromaticContact CZ-CE3 3.6Å; F173-W198 HydrophobicContact CZ-CE3 3.6Å; F173-W198 HydrophobicContact CZ-CG 4.41Å; F173-W198 AromaticContact CZ-CH2 3.98Å; F173-W198 HydrophobicContact CZ-CH2 3.98Å; F173-W198 HydrophobicContact CZ-CZ2 4.08Å; F173-W198 AromaticContact CZ-CZ3 3.74Å; F173-W198 HydrophobicContact CZ-CZ3 3.74Å; F173-L202 HydrophobicContact CD2-CD1 3.85Å; F173-L202 HydrophobicContact CE2-CD1 3.91Å
174	R	95.6	Very high	93.1	Very high	25 Å²	25	68.3 Å²	68.3	9%	0.094	37%	0.365	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-79.7	124.8	179.3	-176.8	127.6	-83.3	-111.8	1.4	109.9	C108 K109 T170 C187 V188 L189	C108-R174 VanDerWaalsContact SG-CG 3.59Å; K109-R174 WeakPolarHBondContact CE-O 3.33Å; K109-R174 WeakPolarHBondContact CG-O 3.42Å; T170-R174 HydrophobicContact CG2-CB 4.39Å; T170-R174 WeakPolarHBondContact O-CB 3.36Å; T170-R174 PolarHBondContact O-N 3.21Å; R174-C187 VanDerWaalsContact NH1-C 3.34Å; R174-C187 PolarHBondContact NH1-O 3.37Å; R174-C187 PolarHBondContact NH1-SG 3.18Å; R174-C187 PolarHBondContact NH2-O 3Å; R174-V188 WeakPolarHBondContact CA-O 3.37Å; R174-V188 VanDerWaalsContact CZ-C 3.45Å; R174-V188 PolarHBondContact NE-O 3.39Å; R174-L189 HydrophobicContact CB-CD2 4.01Å; R174-L189 VanDerWaalsContact NH2-N 3.13Å
175	D	95.1	Very high	92.9	Very high	56 Å²	56	68.8 Å²	68.8	30%	0.299	36%	0.362	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-152	172.8	173.6	-137.5	-41.1	0	0	0	111.6	K109 V188	K109-D175 WeakPolarHBondContact CE-OD2 3.23Å; K109-D175 IonicContact NZ-OD2 2.81Å; K109-D175 PolarHBondContact NZ-OD2 3.27Å; D175-V188 PolarHBondContact N-O 2.65Å; D175-V188 PolarHBondContact O-N 2.86Å
176	T	94.8	Very high	92.7	Very high	48 Å²	48	64 Å²	64	29%	0.294	34%	0.337	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-80.3	133.2	169.7	47.8	0	0	0	0	110.5	W101 C108 T185 A186	W101-T176 HydrophobicContact CG-CG2 4.41Å; C108-T176 HydrophobicContact CB-CG2 4.03Å; T176-T185 HydrophobicContact CG2-CG2 4.22Å; T176-A186 CarbonylContact C-O 3.6Å; T176-A186 VanDerWaalsContact CA-O 3.32Å; T176-A186 WeakPolarHBondContact CA-O 3.02Å
177	Y	93.3	Very high	92.7	Very high	133 Å²	133	61.8 Å²	61.8	52%	0.522	33%	0.327	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-129.1	133	177.4	-173.2	-99.7	0	0	0	109.9	L179 T185 A186	Y177-L179 HydrophobicContact CD1-CD1 3.8Å; Y177-L179 HydrophobicContact CD1-CG 4.23Å; Y177-L179 HydrophobicContact CE1-CG 4.48Å; Y177-T185 CarbonylContact O-C 3.55Å; Y177-T185 WeakPolarHBondContact O-CA 3.47Å; Y177-A186 PolarHBondContact N-O 3.49Å; Y177-A186 PolarHBondContact O-N 3.13Å
178	H	92.8	Very high	92.4	Very high	98 Å²	98	62 Å²	62	45%	0.454	33%	0.328	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-91.6	114.4	-178.8	-169.9	61	0	0	0	110.8	K180 V184 T185	H178-K180 PolarHBondContact O-N 2.91Å; H178-V184 PolarHBondContact ND1-O 2.92Å; H178-T185 PolarHBondContact ND1-OG1 3.32Å; H178-T185 VanDerWaalsContact ND1-OG1 3.12Å
179	L	88.6	Confident	92.2	Very high	11 Å²	11	59 Å²	59	6%	0.058	31%	0.313	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-89.4	99.2	177.8	-76.5	83.9	0	0	0	109.1	H5 Y177 E181 L182 G183 V184 A186	H5-L179 HydrophobicContact CB-CD2 4.38Å; H5-L179 VanDerWaalsContact CE1-CD2 3.48Å; H5-L179 WeakPolarHBondContact CE1-CD2 3.26Å; H5-L179 WeakPolarHBondContact ND1-CD2 3.37Å; Y177-L179 HydrophobicContact CD1-CD1 3.8Å; Y177-L179 HydrophobicContact CD1-CG 4.23Å; Y177-L179 HydrophobicContact CE1-CG 4.48Å; L179-E181 PolarHBondContact O-N 2.9Å; L179-L182 HydrophobicContact CB-CB 4.47Å; L179-L182 HydrophobicContact CD2-CD1 4.12Å; L179-L182 PolarHBondContact O-N 3.48Å; L179-G183 PolarHBondContact O-N 2.99Å; L179-V184 HydrophobicContact CB-CG2 4.29Å; L179-V184 PolarHBondContact N-O 3.36Å; L179-V184 PolarHBondContact O-N 2.96Å; L179-A186 HydrophobicContact CD1-CB 3.57Å
180	K	87.3	Confident	91.9	Very high	192 Å²	192	60.1 Å²	60.1	84%	0.835	32%	0.319	S	S	*	.	T	Hydrogen-bonded Turn	trans	-56	-37.9	-178.7	-67.2	-176	179.9	-179.6	0	113.1	H178 L182 G183	H178-K180 PolarHBondContact O-N 2.91Å; K180-L182 VanDerWaalsContact C-N 3.27Å; K180-L182 PolarHBondContact O-N 3.37Å; K180-G183 PolarHBondContact O-N 2.9Å
181	E	85.4	Confident	91.7	Very high	136 Å²	136	61.6 Å²	61.6	64%	0.636	32%	0.323	S	S	*	.	T	Hydrogen-bonded Turn	trans	-66.6	-27.9	-176.8	-63	-177.5	-158.6	0	0	113.5	L8 L179	L8-E181 VanDerWaalsContact CD2-CD 3.46Å; L8-E181 HydrophobicContact CD2-CG 4.44Å; L8-E181 WeakPolarHBondContact CD2-OE2 3.31Å; L8-E181 WeakPolarHBondContact CG-OE1 3.3Å; L8-E181 WeakPolarHBondContact CG-OE2 3.09Å; L179-E181 PolarHBondContact O-N 2.9Å
182	L	83.1	Confident	91.2	Very high	110 Å²	110	58.9 Å²	58.9	58%	0.576	31%	0.313	S	S	*	.	T	Hydrogen-bonded Turn	trans	-108.7	-8.6	-179	-66.7	172.1	0	0	0	112.4	L179 K180 V184	L179-L182 HydrophobicContact CB-CB 4.47Å; L179-L182 HydrophobicContact CD2-CD1 4.12Å; L179-L182 PolarHBondContact O-N 3.48Å; K180-L182 VanDerWaalsContact C-N 3.27Å; K180-L182 PolarHBondContact O-N 3.37Å; L182-V184 HydrophobicContact CB-CG2 3.84Å; L182-V184 PolarHBondContact O-N 3.35Å
183	G	89	Confident	90.4	Very high	53 Å²	53	61.8 Å²	61.8	55%	0.546	33%	0.326	S	S	.	.	T	Hydrogen-bonded Turn	trans	65.5	17.8	-175.5	0	0	0	0	0	114.3	L179 K180	L179-G183 PolarHBondContact O-N 2.99Å; K180-G183 PolarHBondContact O-N 2.9Å
184	V	91.5	Very high	89.8	Confident	21 Å²	21	65.8 Å²	65.8	13%	0.127	35%	0.354	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-112.5	151.1	-175.6	-59.1	0	0	0	0	112.4	N100 H178 L179 L182	N100-V184 HydrophobicContact CB-CB 4.19Å; N100-V184 HydrophobicContact CB-CG1 4.14Å; H178-V184 PolarHBondContact ND1-O 2.92Å; L179-V184 HydrophobicContact CB-CG2 4.29Å; L179-V184 PolarHBondContact N-O 3.36Å; L179-V184 PolarHBondContact O-N 2.96Å; L182-V184 HydrophobicContact CB-CG2 3.84Å; L182-V184 PolarHBondContact O-N 3.35Å
185	T	94	Very high	89.2	Confident	42 Å²	42	69.2 Å²	69.2	26%	0.258	37%	0.371	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-100.8	106.6	171	-62.9	0	0	0	0	108.8	N100 W101 T176 Y177 H178	N100-T185 PolarHBondContact OD1-N 3.03Å; W101-T185 WeakPolarHBondContact CA-O 3.43Å; W101-T185 VanDerWaalsContact CB-O 3.24Å; W101-T185 WeakPolarHBondContact CB-O 3.28Å; W101-T185 PolarHBondContact N-O 3.33Å; T176-T185 HydrophobicContact CG2-CG2 4.22Å; Y177-T185 CarbonylContact O-C 3.55Å; Y177-T185 WeakPolarHBondContact O-CA 3.47Å; H178-T185 PolarHBondContact ND1-OG1 3.32Å; H178-T185 VanDerWaalsContact ND1-OG1 3.12Å
186	A	93.1	Very high	88.6	Confident	1 Å²	1	70.4 Å²	70.4	1%	0.008	38%	0.382	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-91.9	149.5	-178.3	0	0	0	0	0	112.1	T176 Y177 L179 V188	T176-A186 CarbonylContact C-O 3.6Å; T176-A186 VanDerWaalsContact CA-O 3.32Å; T176-A186 WeakPolarHBondContact CA-O 3.02Å; Y177-A186 PolarHBondContact N-O 3.49Å; Y177-A186 PolarHBondContact O-N 3.13Å; L179-A186 HydrophobicContact CD1-CB 3.57Å; A186-V188 HydrophobicContact CB-CG1 3.83Å
187	C	95.3	Very high	88.4	Confident	4 Å²	4	76.2 Å²	76.2	3%	0.027	40%	0.399	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-94.1	103.2	169.8	174.6	0	0	0	0	109.3	W101 C108 R174	W101-C187 HydrophobicContact CB-CB 3.96Å; W101-C187 HydrophobicContact CD2-CB 3.58Å; W101-C187 HydrophobicContact CE3-CB 3.72Å; W101-C187 HydrophobicContact CG-CB 3.67Å; W101-C187 HydrophobicContact CZ3-CB 4.49Å; C108-C187 WeakPolarHBondContact CA-SG 3.3Å; C108-C187 HydrophobicContact CB-CB 3.88Å; C108-C187 WeakPolarHBondContact CB-SG 3.41Å; C108-C187 WeakPolarHBondContact SG-CA 3.26Å; C108-C187 WeakPolarHBondContact SG-CB 3.46Å; C108-C187 CovalentContact SG-SG 2.03Å; C108-C187 PolarHBondContact SG-SG 3.44Å; R174-C187 VanDerWaalsContact NH1-C 3.34Å; R174-C187 PolarHBondContact NH1-O 3.37Å; R174-C187 PolarHBondContact NH1-SG 3.18Å; R174-C187 PolarHBondContact NH2-O 3Å
188	V	92.1	Very high	88.3	Confident	12 Å²	12	74.3 Å²	74.3	7%	0.073	39%	0.391	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-127.1	169.7	-169.5	-63.8	0	0	0	0	112.4	R174 D175 A186	R174-V188 WeakPolarHBondContact CA-O 3.37Å; R174-V188 VanDerWaalsContact CZ-C 3.45Å; R174-V188 PolarHBondContact NE-O 3.39Å; D175-V188 PolarHBondContact N-O 2.65Å; D175-V188 PolarHBondContact O-N 2.86Å; A186-V188 HydrophobicContact CB-CG1 3.83Å
189	L	91.4	Very high	88.2	Confident	34 Å²	34	71.3 Å²	71.3	18%	0.178	38%	0.377	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-93.4	119.2	165.8	-74.4	157	0	0	0	105.9	A2 F173 R174 Y191	A2-L189 HydrophobicContact CB-CB 3.91Å; A2-L189 HydrophobicContact CB-CD1 4.05Å; A2-L189 HydrophobicContact CB-CG 4.25Å; F173-L189 HydrophobicContact CB-CD2 4.09Å; R174-L189 HydrophobicContact CB-CD2 4.01Å; R174-L189 VanDerWaalsContact NH2-N 3.13Å; L189-Y191 HydrophobicContact CB-CE1 4.41Å; L189-Y191 HydrophobicContact CB-CE2 3.94Å; L189-Y191 WeakPolarHBondContact CD1-OH 3.39Å
190	T	88.6	Confident	88.4	Confident	61 Å²	61	70.9 Å²	70.9	37%	0.374	38%	0.375	S	S	.	.			trans	-107.1	110.6	-177.9	-51.3	0	0	0	0	108.1	F173	F173-T190 PolarHBondContact O-N 2.94Å
191	Y	88.8	Confident	88.8	Confident	48 Å²	48	63.4 Å²	63.4	19%	0.188	35%	0.352	C	S	.	.			trans	-96.8	149.6	177	-55	-67.1	0	0	0	110.5	F173 L189 W198 F199 L202	F173-Y191 HydrophobicContact CB-CD1 4.26Å; F173-Y191 HydrophobicContact CB-CE1 4.09Å; F173-Y191 HydrophobicContact CD1-CD1 4.16Å; F173-Y191 HydrophobicContact CD2-CD1 4.31Å; F173-Y191 HydrophobicContact CD2-CE1 4.14Å; F173-Y191 AromaticContact CG-CD1 3.99Å; F173-Y191 HydrophobicContact CG-CD1 3.99Å; F173-Y191 HydrophobicContact CG-CE1 4.07Å; L189-Y191 HydrophobicContact CB-CE1 4.41Å; L189-Y191 HydrophobicContact CB-CE2 3.94Å; L189-Y191 WeakPolarHBondContact CD1-OH 3.39Å; Y191-W198 HydrophobicContact CD1-CB 3.69Å; Y191-W198 HydrophobicContact CD1-CG 4.49Å; Y191-W198 HydrophobicContact CE1-CB 4.4Å; Y191-W198 HydrophobicContact CG-CB 4.04Å; Y191-F199 HydrophobicContact CD2-CB 3.85Å; Y191-F199 HydrophobicContact CE2-CB 3.66Å; Y191-F199 AromaticContact CE2-CD2 3.64Å; Y191-F199 HydrophobicContact CE2-CD2 3.64Å; Y191-F199 HydrophobicContact CE2-CG 4.12Å; Y191-L202 HydrophobicContact CE1-CD1 3.7Å
192	P	86.2	Confident	89.2	Confident	47 Å²	47	58.6 Å²	58.6	31%	0.305	33%	0.331	S	S	.	.			trans	-57.9	124.7	172.8	-23.1	33	0	0	0	110.9	F173 T194 Q195	F173-P192 HydrophobicContact CE1-CG 4.47Å; P192-T194 PolarHBondContact O-N 3.34Å; P192-Q195 PolarHBondContact O-N 3.08Å
193	P	78.4	Confident	89.7	Confident	130 Å²	130	53.6 Å²	53.6	84%	0.844	31%	0.306	S	S	*	.	T	Hydrogen-bonded Turn	trans	-65.2	-23.8	-176.7	24.6	-33.1	0	0	0	112.7	Q195	P193-Q195 PolarHBondContact O-N 3.21Å
194	T	81.6	Confident	90	Very high	119 Å²	119	53.3 Å²	53.3	73%	0.73	29%	0.291	S	S	*	.	T	Hydrogen-bonded Turn	trans	-72.2	-9.3	176.4	50.6	0	0	0	0	113.5	P192	P192-T194 PolarHBondContact O-N 3.34Å
195	Q	83.9	Confident	90.2	Very high	97 Å²	97	55.2 Å²	55.2	45%	0.453	30%	0.303	S	S	.	.			trans	-132.9	84.2	-173.9	-65.8	-172.1	18.5	0	0	110.9	P192 P193 Y197 W198	P192-Q195 PolarHBondContact O-N 3.08Å; P193-Q195 PolarHBondContact O-N 3.21Å; Q195-Y197 PolarHBondContact O-N 3.39Å; Q195-Y197 VanDerWaalsContact O-N 3.07Å; Q195-W198 VanDerWaalsContact CB-CD1 3.46Å; Q195-W198 PolarHBondContact O-N 3.31Å
196	P	81.4	Confident	90.3	Very high	82 Å²	82	55.7 Å²	55.7	53%	0.532	30%	0.301	S	S	.	.	T	Hydrogen-bonded Turn	trans	-67.4	-13.2	-173	27.8	-35.6	0	0	0	113.8	P200	P196-P200 VanDerWaalsContact O-CD 3.28Å; P196-P200 WeakPolarHBondContact O-CD 3.35Å
197	Y	90.3	Very high	90.4	Very high	169 Å²	169	56.4 Å²	56.4	66%	0.663	31%	0.305	S	S	*	.	T	Hydrogen-bonded Turn	trans	-83.2	-11.4	-174.6	-54.5	-68.7	0	0	0	114.6	Q195 P200 G201 L276	Q195-Y197 PolarHBondContact O-N 3.39Å; Q195-Y197 VanDerWaalsContact O-N 3.07Å; Y197-P200 WeakPolarHBondContact O-CD 3.48Å; Y197-G201 PolarHBondContact O-N 3.37Å; Y197-L276 HydrophobicContact CD1-CD2 4.22Å
198	W	91.6	Very high	90.5	Very high	94 Å²	94	60.1 Å²	60.1	36%	0.356	32%	0.324	S	S	.	.	H	α-helix	trans	-61.7	-49.8	-178.7	-83.5	110.5	0	0	0	113.1	F173 Y191 Q195 L202	F173-W198 HydrophobicContact CE1-CD2 4.46Å; F173-W198 HydrophobicContact CE2-CD2 4.2Å; F173-W198 AromaticContact CE2-CE3 3.67Å; F173-W198 HydrophobicContact CE2-CE3 3.67Å; F173-W198 HydrophobicContact CE2-CH2 4.44Å; F173-W198 AromaticContact CE2-CZ3 3.8Å; F173-W198 HydrophobicContact CE2-CZ3 3.8Å; F173-W198 AromaticContact CZ-CD2 3.71Å; F173-W198 HydrophobicContact CZ-CD2 3.71Å; F173-W198 AromaticContact CZ-CE2 3.93Å; F173-W198 AromaticContact CZ-CE3 3.6Å; F173-W198 HydrophobicContact CZ-CE3 3.6Å; F173-W198 HydrophobicContact CZ-CG 4.41Å; F173-W198 AromaticContact CZ-CH2 3.98Å; F173-W198 HydrophobicContact CZ-CH2 3.98Å; F173-W198 HydrophobicContact CZ-CZ2 4.08Å; F173-W198 AromaticContact CZ-CZ3 3.74Å; F173-W198 HydrophobicContact CZ-CZ3 3.74Å; Y191-W198 HydrophobicContact CD1-CB 3.69Å; Y191-W198 HydrophobicContact CD1-CG 4.49Å; Y191-W198 HydrophobicContact CE1-CB 4.4Å; Y191-W198 HydrophobicContact CG-CB 4.04Å; Q195-W198 VanDerWaalsContact CB-CD1 3.46Å; Q195-W198 PolarHBondContact O-N 3.31Å; W198-L202 HydrophobicContact CE3-CD1 4.17Å; W198-L202 HydrophobicContact CE3-CG 4.4Å; W198-L202 WeakPolarHBondContact O-CB 3.48Å; W198-L202 VanDerWaalsContact O-CG 3.27Å; W198-L202 WeakPolarHBondContact O-CG 3.41Å; W198-L202 PolarHBondContact O-N 3.48Å
199	F	91	Very high	90.7	Very high	34 Å²	34	61.8 Å²	61.8	15%	0.149	33%	0.332	C	S	.	.	H	α-helix	trans	-59.6	-59.4	179.6	172.6	-103.4	0	0	0	112.3	Y191 G201 L202 A203 D271 T275	Y191-F199 HydrophobicContact CD2-CB 3.85Å; Y191-F199 HydrophobicContact CE2-CB 3.66Å; Y191-F199 AromaticContact CE2-CD2 3.64Å; Y191-F199 HydrophobicContact CE2-CD2 3.64Å; Y191-F199 HydrophobicContact CE2-CG 4.12Å; F199-G201 VanDerWaalsContact C-N 3.31Å; F199-G201 PolarHBondContact O-N 3.44Å; F199-L202 PolarHBondContact O-N 3.46Å; F199-A203 VanDerWaalsContact O-CB 3.26Å; F199-A203 WeakPolarHBondContact O-CB 3.26Å; F199-A203 PolarHBondContact O-N 3.44Å; F199-D271 HydrophobicContact CE1-CB 4.41Å; F199-D271 HydrophobicContact CZ-CB 4.28Å; F199-D271 VanDerWaalsContact CZ-OD2 3.28Å; F199-D271 WeakPolarHBondContact CZ-OD2 3.28Å; F199-T275 HydrophobicContact CD1-CG2 4.08Å; F199-T275 WeakPolarHBondContact CE1-OG1 3.34Å
200	P	93.4	Very high	90.9	Very high	2 Å²	2	60.2 Å²	60.2	1%	0.013	32%	0.324	C	S	.	.	H	α-helix	trans	-64	-36.8	-178.1	25.4	-34	0	0	0	111.7	P196 Y197 L202 A203 L204 A272 T275 L276	P196-P200 VanDerWaalsContact O-CD 3.28Å; P196-P200 WeakPolarHBondContact O-CD 3.35Å; Y197-P200 WeakPolarHBondContact O-CD 3.48Å; P200-L202 PolarHBondContact O-N 3.07Å; P200-A203 PolarHBondContact O-N 2.97Å; P200-L204 WeakPolarHBondContact O-CB 3.42Å; P200-L204 WeakPolarHBondContact O-CG 3.43Å; P200-L204 PolarHBondContact O-N 2.95Å; P200-A272 HydrophobicContact CB-CB 4.05Å; P200-T275 HydrophobicContact CG-CG2 4.34Å; P200-L276 HydrophobicContact CB-CD1 4.03Å; P200-L276 HydrophobicContact CB-CD2 4.04Å; P200-L276 HydrophobicContact CB-CG 3.76Å; P200-L276 HydrophobicContact CG-CD2 3.83Å; P200-L276 HydrophobicContact CG-CG 4.07Å
201	G	94.4	Very high	91.2	Very high	35 Å²	35	58.5 Å²	58.5	36%	0.361	31%	0.311	S	S	.	.	H	α-helix	trans	-60.7	-47.1	177	0	0	0	0	0	112.8	Y197 F199 T205	Y197-G201 PolarHBondContact O-N 3.37Å; F199-G201 VanDerWaalsContact C-N 3.31Å; F199-G201 PolarHBondContact O-N 3.44Å; G201-T205 VanDerWaalsContact O-CB 3.3Å; G201-T205 WeakPolarHBondContact O-CB 3.32Å; G201-T205 PolarHBondContact O-N 3.08Å; G201-T205 PolarHBondContact O-OG1 3.21Å
202	L	94	Very high	91.5	Very high	36 Å²	36	60.7 Å²	60.7	19%	0.188	33%	0.325	C	S	.	.	H	α-helix	trans	-71.3	-35.9	178.2	-69.7	172.5	0	0	0	112.4	P169 F173 Y191 W198 F199 P200 K206	P169-L202 HydrophobicContact CB-CD1 4.05Å; P169-L202 HydrophobicContact CB-CD2 3.62Å; P169-L202 HydrophobicContact CG-CD2 3.81Å; F173-L202 HydrophobicContact CD2-CD1 3.85Å; F173-L202 HydrophobicContact CE2-CD1 3.91Å; Y191-L202 HydrophobicContact CE1-CD1 3.7Å; W198-L202 HydrophobicContact CE3-CD1 4.17Å; W198-L202 HydrophobicContact CE3-CG 4.4Å; W198-L202 WeakPolarHBondContact O-CB 3.48Å; W198-L202 VanDerWaalsContact O-CG 3.27Å; W198-L202 WeakPolarHBondContact O-CG 3.41Å; W198-L202 PolarHBondContact O-N 3.48Å; F199-L202 PolarHBondContact O-N 3.46Å; P200-L202 PolarHBondContact O-N 3.07Å; L202-K206 WeakPolarHBondContact O-CB 3.39Å; L202-K206 PolarHBondContact O-N 3.03Å
203	A	93.9	Very high	92	Very high	5 Å²	5	61.8 Å²	61.8	4%	0.041	33%	0.331	C	S	.	.	H	α-helix	trans	-63.2	-45.8	174.4	0	0	0	0	0	111.7	F199 P200 K206 N207 T268 A272	F199-A203 VanDerWaalsContact O-CB 3.26Å; F199-A203 WeakPolarHBondContact O-CB 3.26Å; F199-A203 PolarHBondContact O-N 3.44Å; P200-A203 PolarHBondContact O-N 2.97Å; A203-K206 PolarHBondContact O-N 3.22Å; A203-N207 PolarHBondContact O-N 2.91Å; A203-N207 PolarHBondContact O-ND2 2.86Å; A203-T268 HydrophobicContact CB-CG2 3.81Å; A203-A272 HydrophobicContact CB-CB 3.98Å
204	L	95.9	Very high	92.9	Very high	47 Å²	47	55.7 Å²	55.7	25%	0.246	29%	0.292	C	S	.	.	H	α-helix	trans	-66.8	-42.8	175.9	-69.9	173.9	0	0	0	111.7	P200 K206 N207 I208 F269 A272 L276	P200-L204 WeakPolarHBondContact O-CB 3.42Å; P200-L204 WeakPolarHBondContact O-CG 3.43Å; P200-L204 PolarHBondContact O-N 2.95Å; L204-K206 VanDerWaalsContact C-N 3.29Å; L204-K206 PolarHBondContact O-N 3.42Å; L204-N207 WeakPolarHBondContact O-CB 3.38Å; L204-N207 PolarHBondContact O-N 3.31Å; L204-N207 VanDerWaalsContact O-N 3.12Å; L204-I208 WeakPolarHBondContact O-CG1 3.09Å; L204-I208 PolarHBondContact O-N 2.82Å; L204-F269 HydrophobicContact CD2-CD2 3.59Å; L204-F269 HydrophobicContact CD2-CE2 3.75Å; L204-A272 HydrophobicContact CD2-CB 4.16Å; L204-A272 HydrophobicContact CG-CB 4.06Å; L204-L276 HydrophobicContact CD1-CD1 4.3Å
205	T	95.5	Very high	93.5	Very high	60 Å²	60	54.4 Å²	54.4	37%	0.368	28%	0.276	S	S	.	.	H	α-helix	trans	-56.4	-45.9	174.5	-62.1	0	0	0	0	110.9	G201 I208 L209	G201-T205 VanDerWaalsContact O-CB 3.3Å; G201-T205 WeakPolarHBondContact O-CB 3.32Å; G201-T205 PolarHBondContact O-N 3.08Å; G201-T205 PolarHBondContact O-OG1 3.21Å; T205-I208 PolarHBondContact O-N 3.31Å; T205-L209 HydrophobicContact CG2-CD1 3.64Å; T205-L209 HydrophobicContact CG2-CG 4.24Å; T205-L209 WeakPolarHBondContact O-CB 3.37Å; T205-L209 WeakPolarHBondContact O-CG 3.49Å; T205-L209 PolarHBondContact O-N 3.48Å
206	K	94.8	Very high	94.1	Very high	53 Å²	53	53.1 Å²	53.1	23%	0.23	28%	0.275	C	S	.	.	H	α-helix	trans	-61.6	-44.6	175.7	-174.2	-175.9	-59.7	178.1	0	111.9	L202 A203 L204 I208 A210 F264	L202-K206 WeakPolarHBondContact O-CB 3.39Å; L202-K206 PolarHBondContact O-N 3.03Å; A203-K206 PolarHBondContact O-N 3.22Å; L204-K206 VanDerWaalsContact C-N 3.29Å; L204-K206 PolarHBondContact O-N 3.42Å; K206-I208 VanDerWaalsContact C-N 3.32Å; K206-I208 PolarHBondContact O-N 3.32Å; K206-A210 HydrophobicContact CG-CB 4.31Å; K206-A210 WeakPolarHBondContact O-CA 3.16Å; K206-A210 WeakPolarHBondContact O-CB 3.08Å; K206-A210 PolarHBondContact O-N 3.26Å; K206-F264 HydrophobicContact CD-CE1 4.35Å
207	N	96.3	Very high	94.9	Very high	15 Å²	15	51.6 Å²	51.6	8%	0.08	26%	0.264	C	S	.	.	H	α-helix	trans	-60.2	-40.8	175.6	-84.2	-68.5	0	0	0	112.6	A203 L204 F211 L212 H265	A203-N207 PolarHBondContact O-N 2.91Å; A203-N207 PolarHBondContact O-ND2 2.86Å; L204-N207 WeakPolarHBondContact O-CB 3.38Å; L204-N207 PolarHBondContact O-N 3.31Å; L204-N207 VanDerWaalsContact O-N 3.12Å; N207-F211 VanDerWaalsContact O-CB 3.24Å; N207-F211 WeakPolarHBondContact O-CB 3.3Å; N207-F211 PolarHBondContact O-N 3.48Å; N207-L212 PolarHBondContact O-N 3.35Å; N207-H265 WeakPolarHBondContact OD1-CA 3.26Å; N207-H265 VanDerWaalsContact OD1-CB 3.26Å; N207-H265 WeakPolarHBondContact OD1-CB 3.03Å; N207-H265 PolarHBondContact OD1-ND1 3.09Å; N207-H265 PolarHBondContact OD1-O 3.28Å
208	I	96.9	Very high	95.1	Very high	82 Å²	82	43.7 Å²	43.7	42%	0.421	23%	0.233	S	C	.	.	I	π-helix	trans	-69.9	-52	179.4	-66.3	166.8	0	0	0	110.3	L204 T205 K206 L212 V213	L204-I208 WeakPolarHBondContact O-CG1 3.09Å; L204-I208 PolarHBondContact O-N 2.82Å; T205-I208 PolarHBondContact O-N 3.31Å; K206-I208 VanDerWaalsContact C-N 3.32Å; K206-I208 PolarHBondContact O-N 3.32Å; I208-L212 PolarHBondContact O-N 3.18Å; I208-V213 HydrophobicContact CG2-CG2 3.93Å; I208-V213 WeakPolarHBondContact O-CB 3.45Å; I208-V213 PolarHBondContact O-N 3Å
209	L	96.8	Very high	95.2	Very high	48 Å²	48	40.8 Å²	40.8	25%	0.251	23%	0.23	S	C	.	.	I	π-helix	trans	-84.3	-29.8	-168.1	-62.7	-176.9	0	0	0	114.4	Y120 Y124 M166 T205 P214	Y120-L209 HydrophobicContact CE1-CB 4.26Å; Y124-L209 WeakPolarHBondContact CE1-O 3.31Å; Y124-L209 PolarHBondContact OH-O 3.3Å; Y124-L209 VanDerWaalsContact OH-O 3.07Å; M166-L209 HydrophobicContact CE-CD1 3.75Å; M166-L209 HydrophobicContact SD-CD1 3.5Å; M166-L209 VanDerWaalsContact SD-CD1 3.5Å; T205-L209 HydrophobicContact CG2-CD1 3.64Å; T205-L209 HydrophobicContact CG2-CG 4.24Å; T205-L209 WeakPolarHBondContact O-CB 3.37Å; T205-L209 WeakPolarHBondContact O-CG 3.49Å; T205-L209 PolarHBondContact O-N 3.48Å; L209-P214 WeakPolarHBondContact O-CD 3.42Å; L209-P214 WeakPolarHBondContact O-CG 3.48Å
210	A	95.1	Very high	95.4	Very high	0 Å²	0	41.9 Å²	41.9	0%	0	24%	0.241	C	C	.	.	I	π-helix	trans	-97.3	-10.4	178.2	0	0	0	0	0	113.3	V119 Y120 K206	V119-A210 HydrophobicContact CG1-CB 3.84Å; Y120-A210 HydrophobicContact CD1-CB 3.91Å; Y120-A210 HydrophobicContact CE1-CB 3.71Å; K206-A210 HydrophobicContact CG-CB 4.31Å; K206-A210 WeakPolarHBondContact O-CA 3.16Å; K206-A210 WeakPolarHBondContact O-CB 3.08Å; K206-A210 PolarHBondContact O-N 3.26Å
211	F	94.4	Very high	95.4	Very high	26 Å²	26	42.1 Å²	42.1	11%	0.114	24%	0.243	C	C	.	.	I	π-helix	trans	-132.1	-66.8	-176.1	-167.6	-93.6	0	0	0	113.5	N207 P214 F215 F258 F262 H265	N207-F211 VanDerWaalsContact O-CB 3.24Å; N207-F211 WeakPolarHBondContact O-CB 3.3Å; N207-F211 PolarHBondContact O-N 3.48Å; F211-P214 WeakPolarHBondContact O-CD 3.44Å; F211-F215 WeakPolarHBondContact O-CB 3.31Å; F211-F215 PolarHBondContact O-N 2.99Å; F211-F258 HydrophobicContact CD2-CD1 4.26Å; F211-F258 HydrophobicContact CD2-CE1 4.08Å; F211-F258 AromaticContact CE2-CD1 3.4Å; F211-F258 HydrophobicContact CE2-CD1 3.4Å; F211-F258 VanDerWaalsContact CE2-CD1 3.4Å; F211-F258 AromaticContact CE2-CE1 3.63Å; F211-F258 HydrophobicContact CE2-CE1 3.63Å; F211-F258 AromaticContact CZ-CD1 3.61Å; F211-F258 HydrophobicContact CZ-CD1 3.61Å; F211-F258 AromaticContact CZ-CE1 3.87Å; F211-F258 HydrophobicContact CZ-CE1 3.87Å; F211-F262 AromaticContact CE1-CD2 3.91Å; F211-F262 HydrophobicContact CE1-CD2 3.91Å; F211-F262 HydrophobicContact CE1-CE2 4.44Å; F211-F262 HydrophobicContact CE2-CB 4.01Å; F211-F262 HydrophobicContact CE2-CD2 4.16Å; F211-F262 HydrophobicContact CZ-CB 4.02Å; F211-F262 AromaticContact CZ-CD2 3.4Å; F211-F262 HydrophobicContact CZ-CD2 3.4Å; F211-F262 HydrophobicContact CZ-CE2 4.3Å; F211-F262 HydrophobicContact CZ-CG 4.18Å; F211-H265 HydrophobicContact CB-CB 4.38Å; F211-H265 HydrophobicContact CD2-CB 4.13Å; F211-H265 AromaticContact CD2-CD2 3.29Å; F211-H265 WeakPolarHBondContact CD2-CD2 3.41Å; F211-H265 AromaticContact CD2-CG 3.78Å; F211-H265 HydrophobicContact CG-CB 4.09Å; F211-H265 AromaticContact CG-CD2 3.76Å; F211-H265 AromaticContact CG-CG 3.83Å
212	L	96.1	Very high	95.2	Very high	93 Å²	93	42.6 Å²	42.6	49%	0.487	23%	0.234	S	C	.	.	I	π-helix	trans	-65.4	-48.4	-169.4	-174.8	62.5	0	0	0	113.3	N207 I208 F215 T216	N207-L212 PolarHBondContact O-N 3.35Å; I208-L212 PolarHBondContact O-N 3.18Å; L212-F215 PolarHBondContact O-N 2.93Å; L212-T216 HydrophobicContact CD1-CG2 4.32Å; L212-T216 VanDerWaalsContact O-CG2 3.3Å; L212-T216 WeakPolarHBondContact O-CG2 3.43Å; L212-T216 PolarHBondContact O-N 3.43Å; L212-T216 PolarHBondContact O-OG1 3.25Å; L212-T216 VanDerWaalsContact O-OG1 3.06Å
213	V	96.9	Very high	95	Very high	70 Å²	70	44.7 Å²	44.7	42%	0.424	25%	0.251	S	S	.	.	H	α-helix	trans	-63.5	-51	179	169.4	0	0	0	0	110.9	I208 F215 T216 V217	I208-V213 HydrophobicContact CG2-CG2 3.93Å; I208-V213 WeakPolarHBondContact O-CB 3.45Å; I208-V213 PolarHBondContact O-N 3Å; V213-F215 PolarHBondContact O-N 3.14Å; V213-T216 PolarHBondContact O-N 2.87Å; V213-T216 PolarHBondContact O-OG1 3.48Å; V213-V217 WeakPolarHBondContact O-CG2 3.47Å; V213-V217 PolarHBondContact O-N 2.9Å; V213-V217 VanDerWaalsContact O-N 3.14Å
214	P	96.4	Very high	94.9	Very high	3 Å²	3	51.5 Å²	51.5	2%	0.019	28%	0.275	C	S	.	.	H	α-helix	trans	-57.2	-44.4	173.1	-28.8	36.6	0	0	0	114.4	I123 Y124 L209 F211 T216 V217 I218	I123-P214 HydrophobicContact CD1-CB 3.82Å; I123-P214 HydrophobicContact CG1-CB 3.35Å; I123-P214 HydrophobicContact CG1-CG 3.66Å; I123-P214 HydrophobicContact CG2-CG 4.18Å; Y124-P214 HydrophobicContact CD1-CG 4.39Å; Y124-P214 HydrophobicContact CE1-CG 4.12Å; L209-P214 WeakPolarHBondContact O-CD 3.42Å; L209-P214 WeakPolarHBondContact O-CG 3.48Å; F211-P214 WeakPolarHBondContact O-CD 3.44Å; P214-T216 PolarHBondContact O-N 2.64Å; P214-V217 PolarHBondContact O-N 2.75Å; P214-I218 WeakPolarHBondContact O-CB 3.14Å; P214-I218 WeakPolarHBondContact O-CD1 3.49Å; P214-I218 WeakPolarHBondContact O-CG1 3.4Å; P214-I218 PolarHBondContact O-N 3.05Å
215	F	95.3	Very high	94.6	Very high	91 Å²	91	49.4 Å²	49.4	40%	0.399	27%	0.265	S	S	.	.	H	α-helix	trans	-58.2	-48	179.1	175.9	-100.2	0	0	0	111.8	F211 L212 V213 V217 I218 A219 F258	F211-F215 WeakPolarHBondContact O-CB 3.31Å; F211-F215 PolarHBondContact O-N 2.99Å; L212-F215 PolarHBondContact O-N 2.93Å; V213-F215 PolarHBondContact O-N 3.14Å; F215-V217 PolarHBondContact O-N 2.86Å; F215-I218 PolarHBondContact O-N 2.78Å; F215-A219 WeakPolarHBondContact O-CB 3.4Å; F215-A219 PolarHBondContact O-N 3.37Å; F215-F258 HydrophobicContact CB-CE1 3.67Å; F215-F258 HydrophobicContact CB-CZ 3.67Å; F215-F258 AromaticContact CD2-CD1 3.86Å; F215-F258 HydrophobicContact CD2-CD1 3.86Å; F215-F258 HydrophobicContact CD2-CD2 4.28Å; F215-F258 AromaticContact CD2-CE1 3.47Å; F215-F258 HydrophobicContact CD2-CE1 3.47Å; F215-F258 VanDerWaalsContact CD2-CE1 3.47Å; F215-F258 AromaticContact CD2-CE2 3.89Å; F215-F258 HydrophobicContact CD2-CE2 3.89Å; F215-F258 HydrophobicContact CD2-CG 4.3Å; F215-F258 AromaticContact CD2-CZ 3.52Å; F215-F258 HydrophobicContact CD2-CZ 3.52Å; F215-F258 HydrophobicContact CG-CE1 4.01Å; F215-F258 HydrophobicContact CG-CZ 4.08Å
216	T	95.8	Very high	94.1	Very high	71 Å²	71	47.8 Å²	47.8	44%	0.436	26%	0.259	S	S	.	.	H	α-helix	trans	-63.2	-41.6	179.6	53.2	0	0	0	0	111.8	L212 V213 P214 S220	L212-T216 HydrophobicContact CD1-CG2 4.32Å; L212-T216 VanDerWaalsContact O-CG2 3.3Å; L212-T216 WeakPolarHBondContact O-CG2 3.43Å; L212-T216 PolarHBondContact O-N 3.43Å; L212-T216 PolarHBondContact O-OG1 3.25Å; L212-T216 VanDerWaalsContact O-OG1 3.06Å; V213-T216 PolarHBondContact O-N 2.87Å; V213-T216 PolarHBondContact O-OG1 3.48Å; P214-T216 PolarHBondContact O-N 2.64Å; T216-S220 VanDerWaalsContact O-CB 3.27Å; T216-S220 WeakPolarHBondContact O-CB 3.25Å; T216-S220 PolarHBondContact O-N 2.93Å; T216-S220 PolarHBondContact O-OG 3.17Å
217	V	97.4	Very high	93.8	Very high	50 Å²	50	53.1 Å²	53.1	30%	0.303	28%	0.283	S	S	.	.	H	α-helix	trans	-62.8	-49.8	175.5	175.5	0	0	0	0	110.8	T127 V131 V213 P214 F215 S220 C221	T127-V217 HydrophobicContact CG2-CB 3.95Å; T127-V217 HydrophobicContact CG2-CG1 3.54Å; V131-V217 HydrophobicContact CG2-CG1 3.99Å; V213-V217 WeakPolarHBondContact O-CG2 3.47Å; V213-V217 PolarHBondContact O-N 2.9Å; V213-V217 VanDerWaalsContact O-N 3.14Å; P214-V217 PolarHBondContact O-N 2.75Å; F215-V217 PolarHBondContact O-N 2.86Å; V217-S220 PolarHBondContact O-N 3.22Å; V217-S220 PolarHBondContact O-OG 3.44Å; V217-C221 PolarHBondContact O-N 3Å; V217-C221 PolarHBondContact O-SG 2.89Å
218	I	95.4	Very high	93.2	Very high	3 Å²	3	54.1 Å²	54.1	2%	0.015	29%	0.287	C	S	.	.	H	α-helix	trans	-61.2	-50.4	180	-69	167.4	0	0	0	110.5	I123 I126 T127 P214 F215 S220 C221 Y222 V254 F258	I123-I218 HydrophobicContact CD1-CD1 3.96Å; I126-I218 HydrophobicContact CG2-CD1 3.97Å; T127-I218 HydrophobicContact CG2-CG1 4.38Å; P214-I218 WeakPolarHBondContact O-CB 3.14Å; P214-I218 WeakPolarHBondContact O-CD1 3.49Å; P214-I218 WeakPolarHBondContact O-CG1 3.4Å; P214-I218 PolarHBondContact O-N 3.05Å; F215-I218 PolarHBondContact O-N 2.78Å; I218-S220 VanDerWaalsContact C-N 3.31Å; I218-S220 PolarHBondContact O-N 3.2Å; I218-C221 WeakPolarHBondContact O-CB 3.43Å; I218-C221 PolarHBondContact O-N 2.9Å; I218-C221 VanDerWaalsContact O-N 3.12Å; I218-Y222 HydrophobicContact CG2-CD2 3.72Å; I218-Y222 HydrophobicContact CG2-CE2 3.81Å; I218-Y222 VanDerWaalsContact O-CD2 3.27Å; I218-Y222 WeakPolarHBondContact O-CD2 3.37Å; I218-Y222 PolarHBondContact O-N 3.25Å; I218-V254 HydrophobicContact CG2-CB 4.45Å; I218-V254 HydrophobicContact CG2-CG1 3.6Å; I218-V254 HydrophobicContact CG2-CG2 3.93Å; I218-F258 HydrophobicContact CD1-CE2 4.09Å; I218-F258 HydrophobicContact CD1-CZ 4.16Å; I218-F258 HydrophobicContact CG2-CE2 4.43Å
219	A	93.9	Very high	92.5	Very high	33 Å²	33	55 Å²	55	27%	0.273	29%	0.292	S	S	.	.	H	α-helix	trans	-57.7	-45	178	0	0	0	0	0	111.1	F215 C221 Y222 C223	F215-A219 WeakPolarHBondContact O-CB 3.4Å; F215-A219 PolarHBondContact O-N 3.37Å; A219-C221 VanDerWaalsContact C-N 3.32Å; A219-C221 PolarHBondContact O-N 3.46Å; A219-Y222 PolarHBondContact O-N 3.27Å; A219-C223 VanDerWaalsContact O-CB 3.3Å; A219-C223 WeakPolarHBondContact O-CB 3.29Å; A219-C223 PolarHBondContact O-N 3.47Å; A219-C223 PolarHBondContact O-SG 2.9Å
220	S	94.8	Very high	91.8	Very high	56 Å²	56	60.1 Å²	60.1	39%	0.392	32%	0.319	S	S	.	.	H	α-helix	trans	-61.1	-39.6	177.2	77.6	0	0	0	0	112.7	T216 V217 I218 R224	T216-S220 VanDerWaalsContact O-CB 3.27Å; T216-S220 WeakPolarHBondContact O-CB 3.25Å; T216-S220 PolarHBondContact O-N 2.93Å; T216-S220 PolarHBondContact O-OG 3.17Å; V217-S220 PolarHBondContact O-N 3.22Å; V217-S220 PolarHBondContact O-OG 3.44Å; I218-S220 VanDerWaalsContact C-N 3.31Å; I218-S220 PolarHBondContact O-N 3.2Å; S220-R224 WeakPolarHBondContact O-CB 3.29Å; S220-R224 VanDerWaalsContact O-CG 3.32Å; S220-R224 WeakPolarHBondContact O-CG 3.43Å; S220-R224 PolarHBondContact O-N 2.89Å; S220-R224 VanDerWaalsContact O-N 3.09Å
221	C	93.9	Very high	90.9	Very high	7 Å²	7	62.9 Å²	62.9	5%	0.047	35%	0.348	C	S	.	.	H	α-helix	trans	-61.2	-51.1	176.3	-69.8	0	0	0	0	110.6	Y134 V217 I218 A219 R224 I225	Y134-C221 HydrophobicContact CG-CB 4.48Å; V217-C221 PolarHBondContact O-N 3Å; V217-C221 PolarHBondContact O-SG 2.89Å; I218-C221 WeakPolarHBondContact O-CB 3.43Å; I218-C221 PolarHBondContact O-N 2.9Å; I218-C221 VanDerWaalsContact O-N 3.12Å; A219-C221 VanDerWaalsContact C-N 3.32Å; A219-C221 PolarHBondContact O-N 3.46Å; C221-R224 PolarHBondContact O-N 3.4Å; C221-I225 VanDerWaalsContact O-CG1 3.25Å; C221-I225 WeakPolarHBondContact O-CG1 3.03Å; C221-I225 PolarHBondContact O-N 3.39Å
222	Y	90.2	Very high	89.4	Confident	45 Å²	45	64.8 Å²	64.8	18%	0.176	37%	0.374	C	S	.	.	H	α-helix	trans	-71	-35.6	-177.4	-77.6	-71.1	0	0	0	113.7	I218 A219 R224 I225 G226 V250 V251 V254	I218-Y222 HydrophobicContact CG2-CD2 3.72Å; I218-Y222 HydrophobicContact CG2-CE2 3.81Å; I218-Y222 VanDerWaalsContact O-CD2 3.27Å; I218-Y222 WeakPolarHBondContact O-CD2 3.37Å; I218-Y222 PolarHBondContact O-N 3.25Å; A219-Y222 PolarHBondContact O-N 3.27Å; Y222-R224 VanDerWaalsContact C-N 3.33Å; Y222-R224 PolarHBondContact O-N 2.9Å; Y222-I225 HydrophobicContact CD1-CD1 4.03Å; Y222-I225 HydrophobicContact CE1-CD1 4.22Å; Y222-I225 PolarHBondContact O-N 3.38Å; Y222-G226 PolarHBondContact O-N 3.07Å; Y222-V250 WeakPolarHBondContact OH-CB 3.16Å; Y222-V250 WeakPolarHBondContact OH-CG1 3.42Å; Y222-V251 HydrophobicContact CD1-CG2 3.96Å; Y222-V251 HydrophobicContact CE1-CG2 3.28Å; Y222-V251 PolarHBondContact OH-N 2.85Å; Y222-V254 HydrophobicContact CE2-CG2 4.03Å
223	C	90.1	Very high	87.7	Confident	81 Å²	81	66.9 Å²	66.9	55%	0.547	38%	0.382	S	S	.	.	H	α-helix	trans	-60.4	-43.2	172.1	-73.3	0	0	0	0	111.5	A219 G226 K227	A219-C223 VanDerWaalsContact O-CB 3.3Å; A219-C223 WeakPolarHBondContact O-CB 3.29Å; A219-C223 PolarHBondContact O-N 3.47Å; A219-C223 PolarHBondContact O-SG 2.9Å; C223-G226 PolarHBondContact O-N 3.44Å; C223-K227 WeakPolarHBondContact O-CG 3.38Å; C223-K227 PolarHBondContact O-N 3.47Å
224	R	91	Very high	85.6	Confident	147 Å²	147	69.2 Å²	69.2	56%	0.555	40%	0.398	S	S	*	.	H	α-helix	trans	-70.5	-38.4	177.8	-70	-177.7	-179.5	-161	1.5	112.6	Y134 S220 C221 Y222 G226 K227 H228	Y134-R224 HydrophobicContact CD2-CB 4.05Å; Y134-R224 HydrophobicContact CE2-CB 3.54Å; Y134-R224 HydrophobicContact CE2-CG 4.32Å; Y134-R224 PolarHBondContact OH-NH1 3.49Å; S220-R224 WeakPolarHBondContact O-CB 3.29Å; S220-R224 VanDerWaalsContact O-CG 3.32Å; S220-R224 WeakPolarHBondContact O-CG 3.43Å; S220-R224 PolarHBondContact O-N 2.89Å; S220-R224 VanDerWaalsContact O-N 3.09Å; C221-R224 PolarHBondContact O-N 3.4Å; Y222-R224 VanDerWaalsContact C-N 3.33Å; Y222-R224 PolarHBondContact O-N 2.9Å; R224-G226 VanDerWaalsContact C-N 3.33Å; R224-K227 PolarHBondContact O-N 3.43Å; R224-H228 WeakPolarHBondContact O-CB 3.48Å; R224-H228 PolarHBondContact O-N 3.47Å
225	I	88.9	Confident	83.6	Confident	4 Å²	4	72.4 Å²	72.4	2%	0.021	42%	0.42	C	S	.	.	H	α-helix	trans	-57.9	-48.9	171.6	-68.8	164.1	0	0	0	109.8	Y134 I137 V138 C221 Y222 K227 H228 L229 M247	Y134-I225 HydrophobicContact CD2-CG1 4.11Å; I137-I225 HydrophobicContact CD1-CD1 4.32Å; I137-I225 HydrophobicContact CD1-CG1 4.47Å; I137-I225 HydrophobicContact CD1-CG2 4.02Å; I137-I225 HydrophobicContact CG2-CG2 4.33Å; V138-I225 HydrophobicContact CG2-CG1 4.49Å; C221-I225 VanDerWaalsContact O-CG1 3.25Å; C221-I225 WeakPolarHBondContact O-CG1 3.03Å; C221-I225 PolarHBondContact O-N 3.39Å; Y222-I225 HydrophobicContact CD1-CD1 4.03Å; Y222-I225 HydrophobicContact CE1-CD1 4.22Å; Y222-I225 PolarHBondContact O-N 3.38Å; I225-K227 PolarHBondContact O-N 3.34Å; I225-H228 PolarHBondContact O-N 3.31Å; I225-L229 HydrophobicContact CG2-CD1 3.86Å; I225-L229 HydrophobicContact CG2-CG 4.36Å; I225-L229 WeakPolarHBondContact O-CG 3.46Å; I225-L229 PolarHBondContact O-N 2.94Å; I225-M247 HydrophobicContact CG2-SD 4.32Å
226	G	86.2	Confident	81.5	Confident	25 Å²	25	75.1 Å²	75.1	26%	0.258	44%	0.438	S	S	.	.	H	α-helix	trans	-57.1	-50.4	178	0	0	0	0	0	112.1	Y222 C223 R224 H228 L229 L230	Y222-G226 PolarHBondContact O-N 3.07Å; C223-G226 PolarHBondContact O-N 3.44Å; R224-G226 VanDerWaalsContact C-N 3.33Å; G226-H228 VanDerWaalsContact C-N 3.31Å; G226-H228 PolarHBondContact O-N 2.95Å; G226-L229 PolarHBondContact O-N 3.32Å; G226-L229 VanDerWaalsContact O-N 3.17Å; G226-L230 WeakPolarHBondContact O-CD1 3.31Å; G226-L230 PolarHBondContact O-N 3Å
227	K	87.3	Confident	79.2	Confident	165 Å²	165	78.2 Å²	78.2	72%	0.717	45%	0.452	S	S	*	.	H	α-helix	trans	-57.8	-41.6	176.4	-73.5	-178.5	177.6	-173.8	0	112.9	C223 R224 I225 L230 G231	C223-K227 WeakPolarHBondContact O-CG 3.38Å; C223-K227 PolarHBondContact O-N 3.47Å; R224-K227 PolarHBondContact O-N 3.43Å; I225-K227 PolarHBondContact O-N 3.34Å; K227-L230 PolarHBondContact O-N 3.17Å; K227-G231 PolarHBondContact O-N 3.43Å
228	H	84.4	Confident	76.7	Confident	37 Å²	37	85.3 Å²	85.3	17%	0.171	48%	0.479	C	S	.	.	H	α-helix	trans	-64.4	-40.4	177.8	-176.4	-81.4	0	0	0	112.1	V138 R224 I225 G226	V138-H228 HydrophobicContact CG2-CB 4.02Å; R224-H228 WeakPolarHBondContact O-CB 3.48Å; R224-H228 PolarHBondContact O-N 3.47Å; I225-H228 PolarHBondContact O-N 3.31Å; G226-H228 VanDerWaalsContact C-N 3.31Å; G226-H228 PolarHBondContact O-N 2.95Å
229	L	82.6	Confident	74.8	Confident	100 Å²	100	87.4 Å²	87.4	52%	0.524	49%	0.494	S	S	.	.	H	α-helix	trans	-71.3	-36.8	178.2	-66.9	174.2	0	0	0	112.7	I137 I225 G226	I137-L229 HydrophobicContact CG2-CD2 4.4Å; I225-L229 HydrophobicContact CG2-CD1 3.86Å; I225-L229 HydrophobicContact CG2-CG 4.36Å; I225-L229 WeakPolarHBondContact O-CG 3.46Å; I225-L229 PolarHBondContact O-N 2.94Å; G226-L229 PolarHBondContact O-N 3.32Å; G226-L229 VanDerWaalsContact O-N 3.17Å
230	L	81.8	Confident	73.2	Confident	155 Å²	155	88.9 Å²	88.9	81%	0.812	50%	0.502	S	S	*	.	H	α-helix	trans	-74.8	-28.3	176.8	-85.2	85.2	0	0	0	113.1	G226 K227 G232	G226-L230 WeakPolarHBondContact O-CD1 3.31Å; G226-L230 PolarHBondContact O-N 3Å; K227-L230 PolarHBondContact O-N 3.17Å; L230-G232 PolarHBondContact O-N 2.99Å; L230-G232 VanDerWaalsContact O-N 3.14Å
231	G	76.4	Confident	71.8	Confident	59 Å²	59	89.5 Å²	89.5	61%	0.608	51%	0.507	S	S	*	.	T	Hydrogen-bonded Turn	trans	-73.3	5.5	-177.4	0	0	0	0	0	115.7	K227 Q233	K227-G231 PolarHBondContact O-N 3.43Å; G231-Q233 PolarHBondContact O-N 2.87Å; G231-Q233 VanDerWaalsContact O-N 3.08Å
232	G	62.3	Low	70.4	Confident	65 Å²	65	92.9 Å²	92.9	67%	0.67	52%	0.524	S	S	*	.	T	Hydrogen-bonded Turn	trans	65.6	12.7	170.4	0	0	0	0	0	116	L230	L230-G232 PolarHBondContact O-N 2.99Å; L230-G232 VanDerWaalsContact O-N 3.14Å
233	Q	61	Low	69.5	Low	138 Å²	138	92.8 Å²	92.8	65%	0.645	53%	0.527	S	S	*	.			trans	-63.5	128.4	174.5	-84.7	-153.3	-19.3	0	0	109.4	G231 S235	G231-Q233 PolarHBondContact O-N 2.87Å; G231-Q233 VanDerWaalsContact O-N 3.08Å; Q233-S235 VanDerWaalsContact C-N 3.34Å; Q233-S235 PolarHBondContact O-N 2.97Å
234	P	53	Low	68.7	Low	119 Å²	119	92.1 Å²	92.1	77%	0.773	52%	0.517	S	S	*	.			trans	-66.6	99.5	176	26.9	-30.3	0	0	0	107	L236	P234-L236 PolarHBondContact O-N 3.48Å
235	S	54.4	Low	67.8	Low	69 Å²	69	88.4 Å²	88.4	48%	0.483	50%	0.503	S	S	.	.			trans	-54.4	116.5	161.6	52.9	0	0	0	0	105.8	Q233 D237	Q233-S235 VanDerWaalsContact C-N 3.34Å; Q233-S235 PolarHBondContact O-N 2.97Å; S235-D237 CarbonylContact O-C 3.53Å; S235-D237 PolarHBondContact O-N 3.14Å; S235-D237 PolarHBondContact OG-O 3.08Å
236	L	51	Low	67.2	Low	149 Å²	149	89.8 Å²	89.8	78%	0.78	51%	0.512	S	S	*	.	S	Bend	trans	-56.3	6.8	-173	-99.3	160.5	0	0	0	115.7	P234	P234-L236 PolarHBondContact O-N 3.48Å
237	D	46.8	Very low	66.9	Low	135 Å²	135	90.4 Å²	90.4	72%	0.722	51%	0.509	S	S	*	.	S	Bend	trans	-149.6	141.3	158.8	-121.6	-28.6	0	0	0	108.8	S235 S239	S235-D237 CarbonylContact O-C 3.53Å; S235-D237 PolarHBondContact O-N 3.14Å; S235-D237 PolarHBondContact OG-O 3.08Å; D237-S239 PolarHBondContact O-N 2.9Å
238	K	45.8	Very low	66.6	Low	199 Å²	199	88.8 Å²	88.8	87%	0.865	50%	0.502	S	S	*	.			trans	-40.7	104.1	164.5	-159.7	174.9	-169.6	174.3	0	107.5	S240	K238-S240 PolarHBondContact O-N 3.41Å
239	S	55.1	Low	66.6	Low	47 Å²	47	87.7 Å²	87.7	33%	0.329	50%	0.497	S	S	.	.			trans	-39.5	111.4	-169.7	-177.2	0	0	0	0	109.7	D237 S241 D244	D237-S239 PolarHBondContact O-N 2.9Å; S239-S241 PolarHBondContact O-N 3.14Å; S239-D244 PolarHBondContact OG-OD1 3.02Å
240	S	60.2	Low	66.6	Low	65 Å²	65	83 Å²	83	46%	0.455	47%	0.473	S	S	.	.			trans	-52.8	131.5	-178.7	69.6	0	0	0	0	107.5	K238 N242 L243	K238-S240 PolarHBondContact O-N 3.41Å; S240-N242 CarbonylContact O-C 3.35Å; S240-N242 PolarHBondContact O-N 2.98Å; S240-L243 PolarHBondContact O-N 3.35Å; S240-L243 PolarHBondContact OG-N 3.37Å
241	S	64.5	Low	66.8	Low	69 Å²	69	78 Å²	78	48%	0.483	45%	0.448	S	S	.	.	H	α-helix	trans	-50.2	-25.4	-178.8	57.7	0	0	0	0	112.9	S239 R245	S239-S241 PolarHBondContact O-N 3.14Å; S241-R245 WeakPolarHBondContact O-CD 3.4Å; S241-R245 WeakPolarHBondContact O-CG 3.35Å; S241-R245 PolarHBondContact O-N 3.46Å; S241-R245 PolarHBondContact O-NE 2.95Å
242	N	66.2	Low	67.4	Low	78 Å²	78	76.3 Å²	76.3	42%	0.417	43%	0.428	S	S	.	.	H	α-helix	trans	-67.5	-39.6	173	-69.4	-46.6	0	0	0	114.7	S240 R245 V246	S240-N242 CarbonylContact O-C 3.35Å; S240-N242 PolarHBondContact O-N 2.98Å; N242-R245 PolarHBondContact O-N 3.37Å; N242-V246 VanDerWaalsContact O-CG2 3.3Å; N242-V246 WeakPolarHBondContact O-CG2 3.26Å; N242-V246 PolarHBondContact O-N 3.21Å
243	L	69.8	Low	68.6	Low	43 Å²	43	73.2 Å²	73.2	23%	0.225	40%	0.396	C	S	.	.	H	α-helix	trans	-67.4	-44.4	-179	-176.9	59	0	0	0	111.3	R133 A136 I137 S240 R245 V246 M247	R133-L243 VanDerWaalsContact NH1-CD1 3.32Å; A136-L243 HydrophobicContact CB-CD1 4.46Å; I137-L243 HydrophobicContact CG1-CD1 4.45Å; I137-L243 HydrophobicContact CG1-CD2 4.21Å; I137-L243 HydrophobicContact CG1-CG 4.45Å; S240-L243 PolarHBondContact O-N 3.35Å; S240-L243 PolarHBondContact OG-N 3.37Å; L243-R245 VanDerWaalsContact C-N 3.34Å; L243-R245 PolarHBondContact O-N 3.29Å; L243-V246 PolarHBondContact O-N 2.96Å; L243-M247 WeakPolarHBondContact O-CB 3.39Å; L243-M247 PolarHBondContact O-N 2.71Å
244	D	73	Confident	69.9	Low	66 Å²	66	67.2 Å²	67.2	35%	0.353	37%	0.369	S	S	.	.	H	α-helix	trans	-61.1	-41.5	175.3	-75.4	1.5	0	0	0	111.9	S239 M247 K248	S239-D244 PolarHBondContact OG-OD1 3.02Å; D244-M247 PolarHBondContact O-N 3.12Å; D244-K248 WeakPolarHBondContact O-CG 3.41Å; D244-K248 PolarHBondContact O-N 3.43Å
245	R	73.9	Confident	71.8	Confident	69 Å²	69	66.7 Å²	66.7	26%	0.26	36%	0.359	S	S	.	.	H	α-helix	trans	-61.9	-48.6	176	-72.7	164.8	-168.4	-163.7	-1.7	111.7	S241 N242 L243 M247 K248 M249 E319	S241-R245 WeakPolarHBondContact O-CD 3.4Å; S241-R245 WeakPolarHBondContact O-CG 3.35Å; S241-R245 PolarHBondContact O-N 3.46Å; S241-R245 PolarHBondContact O-NE 2.95Å; N242-R245 PolarHBondContact O-N 3.37Å; L243-R245 VanDerWaalsContact C-N 3.34Å; L243-R245 PolarHBondContact O-N 3.29Å; R245-M247 VanDerWaalsContact C-N 3.29Å; R245-M247 PolarHBondContact O-N 3.34Å; R245-K248 PolarHBondContact O-N 3.26Å; R245-M249 WeakPolarHBondContact O-CB 3.21Å; R245-M249 PolarHBondContact O-N 3.28Å; R245-E319 IonicContact CZ-OE1 3.89Å; R245-E319 IonicContact NH1-OE1 2.82Å; R245-E319 PolarHBondContact NH1-OE1 3.27Å; R245-E319 IonicContact NH1-OE2 3.9Å
246	V	75.3	Confident	73.6	Confident	34 Å²	34	64.1 Å²	64.1	21%	0.206	34%	0.342	C	S	.	.	H	α-helix	trans	-63.7	-38.6	178.1	-180	0	0	0	0	110.3	R133 N242 L243 M249 V250	R133-V246 VanDerWaalsContact NH1-CG1 3.34Å; N242-V246 VanDerWaalsContact O-CG2 3.3Å; N242-V246 WeakPolarHBondContact O-CG2 3.26Å; N242-V246 PolarHBondContact O-N 3.21Å; L243-V246 PolarHBondContact O-N 2.96Å; V246-M249 HydrophobicContact CG1-CE 4.25Å; V246-M249 PolarHBondContact O-N 3.44Å; V246-V250 HydrophobicContact CG1-CG2 4.36Å; V246-V250 WeakPolarHBondContact O-CG2 3.46Å; V246-V250 PolarHBondContact O-N 3.46Å
247	M	79.1	Confident	75.5	Confident	38 Å²	38	57 Å²	57	19%	0.187	31%	0.305	C	S	.	.	H	α-helix	trans	-60.6	-50.5	174.9	-176.2	-173.6	70.7	0	0	111.9	I137 I225 L243 D244 R245 M249 V250 V251	I137-M247 HydrophobicContact CD1-CG 4.33Å; I137-M247 HydrophobicContact CD1-SD 3.88Å; I225-M247 HydrophobicContact CG2-SD 4.32Å; L243-M247 WeakPolarHBondContact O-CB 3.39Å; L243-M247 PolarHBondContact O-N 2.71Å; D244-M247 PolarHBondContact O-N 3.12Å; R245-M247 VanDerWaalsContact C-N 3.29Å; R245-M247 PolarHBondContact O-N 3.34Å; M247-M249 VanDerWaalsContact C-N 3.27Å; M247-M249 PolarHBondContact O-N 3.33Å; M247-V250 PolarHBondContact O-N 2.73Å; M247-V250 VanDerWaalsContact O-N 3.17Å; M247-V251 HydrophobicContact CG-CG2 4.49Å; M247-V251 WeakPolarHBondContact O-CG2 3.37Å; M247-V251 PolarHBondContact O-N 3.04Å
248	K	82.3	Confident	77.7	Confident	131 Å²	131	51.9 Å²	51.9	57%	0.57	28%	0.276	S	S	*	.	H	α-helix	trans	-56.2	-42.7	176.7	-74.3	175.5	-179.4	179.7	0	111.7	D244 R245 V251 A252 V313	D244-K248 WeakPolarHBondContact O-CG 3.41Å; D244-K248 PolarHBondContact O-N 3.43Å; R245-K248 PolarHBondContact O-N 3.26Å; K248-V251 PolarHBondContact O-N 3.11Å; K248-A252 WeakPolarHBondContact O-CB 3.37Å; K248-A252 PolarHBondContact O-N 3.44Å; K248-V313 HydrophobicContact CB-CG1 4.14Å
249	M	83.1	Confident	80.1	Confident	13 Å²	13	47 Å²	47	6%	0.064	26%	0.263	C	S	.	.	H	α-helix	trans	-61.9	-48.2	175.6	-178.4	-156.4	76.4	0	0	112	I74 R245 V246 M247 V251 A252 V253 Y310 V313	I74-M249 HydrophobicContact CD1-CE 3.78Å; I74-M249 HydrophobicContact CD1-SD 4.24Å; I74-M249 HydrophobicContact CG1-CE 4.49Å; R245-M249 WeakPolarHBondContact O-CB 3.21Å; R245-M249 PolarHBondContact O-N 3.28Å; V246-M249 HydrophobicContact CG1-CE 4.25Å; V246-M249 PolarHBondContact O-N 3.44Å; M247-M249 VanDerWaalsContact C-N 3.27Å; M247-M249 PolarHBondContact O-N 3.33Å; M249-V251 PolarHBondContact O-N 2.85Å; M249-A252 PolarHBondContact O-N 2.95Å; M249-V253 VanDerWaalsContact O-CG2 3.31Å; M249-V253 WeakPolarHBondContact O-CG2 3.4Å; M249-V253 PolarHBondContact O-N 3.22Å; M249-Y310 HydrophobicContact CG-CD1 4.13Å; M249-Y310 HydrophobicContact SD-CD1 3.8Å; M249-Y310 HydrophobicContact SD-CE1 4.49Å; M249-V313 HydrophobicContact CB-CG1 4.4Å
250	V	82.9	Confident	82	Confident	3 Å²	3	44.9 Å²	44.9	2%	0.018	25%	0.248	C	C	.	.	H	α-helix	trans	-64.9	-40.2	179.3	-174.6	0	0	0	0	111	M129 R133 Y222 V246 M247 A252 V253 V254	M129-V250 HydrophobicContact CB-CG1 4.01Å; M129-V250 HydrophobicContact CB-CG2 4.44Å; R133-V250 HydrophobicContact CG-CB 4.18Å; R133-V250 HydrophobicContact CG-CG1 4.36Å; R133-V250 HydrophobicContact CG-CG2 3.85Å; Y222-V250 WeakPolarHBondContact OH-CB 3.16Å; Y222-V250 WeakPolarHBondContact OH-CG1 3.42Å; V246-V250 HydrophobicContact CG1-CG2 4.36Å; V246-V250 WeakPolarHBondContact O-CG2 3.46Å; V246-V250 PolarHBondContact O-N 3.46Å; M247-V250 PolarHBondContact O-N 2.73Å; M247-V250 VanDerWaalsContact O-N 3.17Å; V250-A252 VanDerWaalsContact C-N 3.34Å; V250-A252 PolarHBondContact O-N 3.41Å; V250-V253 PolarHBondContact O-N 2.88Å; V250-V254 HydrophobicContact CG1-CG2 4.39Å; V250-V254 WeakPolarHBondContact O-CB 3.13Å; V250-V254 VanDerWaalsContact O-CG2 3.26Å; V250-V254 WeakPolarHBondContact O-CG2 3.22Å; V250-V254 PolarHBondContact O-N 3.46Å
251	V	87.2	Confident	83.7	Confident	50 Å²	50	41.9 Å²	41.9	30%	0.303	23%	0.227	S	C	.	.	H	α-helix	trans	-59.2	-45.9	174	172.1	0	0	0	0	111	Y222 M247 K248 M249 V253 V254 L255	Y222-V251 HydrophobicContact CD1-CG2 3.96Å; Y222-V251 HydrophobicContact CE1-CG2 3.28Å; Y222-V251 PolarHBondContact OH-N 2.85Å; M247-V251 HydrophobicContact CG-CG2 4.49Å; M247-V251 WeakPolarHBondContact O-CG2 3.37Å; M247-V251 PolarHBondContact O-N 3.04Å; K248-V251 PolarHBondContact O-N 3.11Å; M249-V251 PolarHBondContact O-N 2.85Å; V251-V253 VanDerWaalsContact C-N 3.34Å; V251-V253 PolarHBondContact O-N 3.49Å; V251-V254 WeakPolarHBondContact O-CB 3.31Å; V251-V254 PolarHBondContact O-N 3.32Å; V251-L255 HydrophobicContact CG1-CD1 4Å; V251-L255 HydrophobicContact CG1-CG 4.36Å; V251-L255 WeakPolarHBondContact O-CG 3.27Å; V251-L255 PolarHBondContact O-N 3.46Å
252	A	88.4	Confident	85.2	Confident	22 Å²	22	43.9 Å²	43.9	18%	0.182	23%	0.227	C	C	.	.	H	α-helix	trans	-62.2	-41.5	178.9	0	0	0	0	0	112	K248 M249 V250 L255 A256 L309 V313	K248-A252 WeakPolarHBondContact O-CB 3.37Å; K248-A252 PolarHBondContact O-N 3.44Å; M249-A252 PolarHBondContact O-N 2.95Å; V250-A252 VanDerWaalsContact C-N 3.34Å; V250-A252 PolarHBondContact O-N 3.41Å; A252-L255 PolarHBondContact O-N 3.2Å; A252-A256 WeakPolarHBondContact O-CB 3.41Å; A252-A256 PolarHBondContact O-N 3.2Å; A252-L309 HydrophobicContact CB-CD1 4.45Å; A252-L309 HydrophobicContact CB-CD2 4.05Å; A252-V313 HydrophobicContact CB-CG1 4.16Å; A252-V313 HydrophobicContact CB-CG2 4.2Å
253	V	86.9	Confident	86.6	Confident	1 Å²	1	42.1 Å²	42.1	1%	0.006	22%	0.22	C	C	.	.	H	α-helix	trans	-64.1	-41.4	176.2	171.6	0	0	0	0	111.3	I126 M129 M249 V250 V251 A256 F257 L309 Y310	I126-V253 HydrophobicContact CD1-CG1 3.86Å; I126-V253 HydrophobicContact CG1-CG1 3.84Å; M129-V253 HydrophobicContact CE-CG1 4.34Å; M249-V253 VanDerWaalsContact O-CG2 3.31Å; M249-V253 WeakPolarHBondContact O-CG2 3.4Å; M249-V253 PolarHBondContact O-N 3.22Å; V250-V253 PolarHBondContact O-N 2.88Å; V251-V253 VanDerWaalsContact C-N 3.34Å; V251-V253 PolarHBondContact O-N 3.49Å; V253-A256 PolarHBondContact O-N 3.11Å; V253-F257 WeakPolarHBondContact O-CB 3.25Å; V253-F257 PolarHBondContact O-N 3.48Å; V253-L309 HydrophobicContact CB-CD1 4.32Å; V253-L309 HydrophobicContact CG2-CB 4.05Å; V253-L309 HydrophobicContact CG2-CD1 3.83Å; V253-Y310 HydrophobicContact CG2-CD1 4.44Å; V253-Y310 HydrophobicContact CG2-CE1 3.77Å
254	V	89.5	Confident	87.9	Confident	12 Å²	12	41.1 Å²	41.1	7%	0.073	21%	0.213	C	C	.	.	H	α-helix	trans	-60.9	-48.8	175.3	164	0	0	0	0	111	I126 I218 Y222 V250 V251 F257 F258	I126-V254 HydrophobicContact CG2-CG2 3.59Å; I218-V254 HydrophobicContact CG2-CB 4.45Å; I218-V254 HydrophobicContact CG2-CG1 3.6Å; I218-V254 HydrophobicContact CG2-CG2 3.93Å; Y222-V254 HydrophobicContact CE2-CG2 4.03Å; V250-V254 HydrophobicContact CG1-CG2 4.39Å; V250-V254 WeakPolarHBondContact O-CB 3.13Å; V250-V254 VanDerWaalsContact O-CG2 3.26Å; V250-V254 WeakPolarHBondContact O-CG2 3.22Å; V250-V254 PolarHBondContact O-N 3.46Å; V251-V254 WeakPolarHBondContact O-CB 3.31Å; V251-V254 PolarHBondContact O-N 3.32Å; V254-F257 PolarHBondContact O-N 3.26Å; V254-F258 HydrophobicContact CG1-CD2 3.82Å; V254-F258 HydrophobicContact CG1-CE2 3.86Å; V254-F258 WeakPolarHBondContact O-CD2 3.24Å; V254-F258 PolarHBondContact O-N 2.86Å; V254-F258 VanDerWaalsContact O-N 3.07Å
255	L	92.5	Very high	88.9	Confident	107 Å²	107	38.1 Å²	38.1	56%	0.56	20%	0.197	S	C	*	.	H	α-helix	trans	-62.2	-44.9	178.7	-70.2	174.6	0	0	0	111.5	V251 A252 F257 F258 V259	V251-L255 HydrophobicContact CG1-CD1 4Å; V251-L255 HydrophobicContact CG1-CG 4.36Å; V251-L255 WeakPolarHBondContact O-CG 3.27Å; V251-L255 PolarHBondContact O-N 3.46Å; A252-L255 PolarHBondContact O-N 3.2Å; L255-F257 VanDerWaalsContact C-N 3.34Å; L255-F257 PolarHBondContact O-N 3.42Å; L255-F258 PolarHBondContact O-N 2.86Å; L255-V259 WeakPolarHBondContact O-CB 3.3Å; L255-V259 VanDerWaalsContact O-CG2 3.29Å; L255-V259 WeakPolarHBondContact O-CG2 3.49Å; L255-V259 PolarHBondContact O-N 2.82Å
256	A	92.3	Very high	90	Very high	15 Å²	15	37.3 Å²	37.3	12%	0.124	20%	0.2	C	C	.	.	H	α-helix	trans	-59.9	-43.9	177	0	0	0	0	0	111.8	A252 V253 F258 V259 C260 I305 L309	A252-A256 WeakPolarHBondContact O-CB 3.41Å; A252-A256 PolarHBondContact O-N 3.2Å; V253-A256 PolarHBondContact O-N 3.11Å; A256-F258 PolarHBondContact O-N 3.21Å; A256-V259 PolarHBondContact O-N 2.98Å; A256-C260 VanDerWaalsContact O-CB 3.26Å; A256-C260 WeakPolarHBondContact O-CB 3.4Å; A256-C260 PolarHBondContact O-N 3.47Å; A256-C260 PolarHBondContact O-SG 3.14Å; A256-I305 HydrophobicContact CB-CG2 3.91Å; A256-L309 HydrophobicContact CB-CD1 3.67Å
257	F	91	Very high	91	Very high	0 Å²	0	36.4 Å²	36.4	0%	0	19%	0.194	C	C	.	.	H	α-helix	trans	-58.2	-50.2	176.3	-179.1	-85.4	0	0	0	111.7	I123 I126 V253 V254 L255 C260 W261 N302	I123-F257 HydrophobicContact CB-CE1 4.15Å; I123-F257 HydrophobicContact CB-CE2 3.75Å; I123-F257 HydrophobicContact CB-CZ 3.49Å; I123-F257 VanDerWaalsContact CB-CZ 3.49Å; I123-F257 HydrophobicContact CD1-CD1 3.52Å; I123-F257 HydrophobicContact CD1-CD2 4.24Å; I123-F257 HydrophobicContact CD1-CE1 3.27Å; I123-F257 HydrophobicContact CD1-CE2 4.02Å; I123-F257 HydrophobicContact CD1-CG 4.03Å; I123-F257 HydrophobicContact CD1-CZ 3.56Å; I123-F257 HydrophobicContact CG1-CD1 4.41Å; I123-F257 HydrophobicContact CG1-CE1 3.68Å; I123-F257 HydrophobicContact CG1-CE2 4.19Å; I123-F257 HydrophobicContact CG1-CZ 3.56Å; I126-F257 HydrophobicContact CD1-CB 3.84Å; I126-F257 HydrophobicContact CD1-CD2 3.65Å; I126-F257 HydrophobicContact CD1-CG 3.92Å; V253-F257 WeakPolarHBondContact O-CB 3.25Å; V253-F257 PolarHBondContact O-N 3.48Å; V254-F257 PolarHBondContact O-N 3.26Å; L255-F257 VanDerWaalsContact C-N 3.34Å; L255-F257 PolarHBondContact O-N 3.42Å; F257-C260 PolarHBondContact O-N 3.44Å; F257-W261 AromaticContact CD2-CD1 3.5Å; F257-W261 VanDerWaalsContact CD2-CD1 3.5Å; F257-W261 HydrophobicContact CD2-CG 4.47Å; F257-W261 AromaticContact CD2-NE1 3.96Å; F257-W261 HydrophobicContact CE1-CB 4.15Å; F257-W261 HydrophobicContact CE1-CG 4.36Å; F257-W261 AromaticContact CE2-CD1 3.33Å; F257-W261 HydrophobicContact CE2-CG 4.02Å; F257-W261 AromaticContact CE2-NE1 3.67Å; F257-W261 HydrophobicContact CZ-CB 4.17Å; F257-W261 AromaticContact CZ-CD1 3.69Å; F257-W261 AromaticContact CZ-CG 3.93Å; F257-W261 HydrophobicContact CZ-CG 3.93Å; F257-W261 WeakPolarHBondContact O-CB 3.49Å; F257-W261 PolarHBondContact O-N 3.46Å; F257-N302 VanDerWaalsContact CA-OD1 3.31Å; F257-N302 WeakPolarHBondContact CA-OD1 3.21Å
258	F	93.1	Very high	91.7	Very high	27 Å²	27	35.1 Å²	35.1	12%	0.118	19%	0.188	C	C	.	.	H	α-helix	trans	-67.3	-41.9	-178.1	-76.3	-63.1	0	0	0	112.3	F211 F215 I218 V254 L255 A256 C260 F262	F211-F258 HydrophobicContact CD2-CD1 4.26Å; F211-F258 HydrophobicContact CD2-CE1 4.08Å; F211-F258 AromaticContact CE2-CD1 3.4Å; F211-F258 HydrophobicContact CE2-CD1 3.4Å; F211-F258 VanDerWaalsContact CE2-CD1 3.4Å; F211-F258 AromaticContact CE2-CE1 3.63Å; F211-F258 HydrophobicContact CE2-CE1 3.63Å; F211-F258 AromaticContact CZ-CD1 3.61Å; F211-F258 HydrophobicContact CZ-CD1 3.61Å; F211-F258 AromaticContact CZ-CE1 3.87Å; F211-F258 HydrophobicContact CZ-CE1 3.87Å; F215-F258 HydrophobicContact CB-CE1 3.67Å; F215-F258 HydrophobicContact CB-CZ 3.67Å; F215-F258 AromaticContact CD2-CD1 3.86Å; F215-F258 HydrophobicContact CD2-CD1 3.86Å; F215-F258 HydrophobicContact CD2-CD2 4.28Å; F215-F258 AromaticContact CD2-CE1 3.47Å; F215-F258 HydrophobicContact CD2-CE1 3.47Å; F215-F258 VanDerWaalsContact CD2-CE1 3.47Å; F215-F258 AromaticContact CD2-CE2 3.89Å; F215-F258 HydrophobicContact CD2-CE2 3.89Å; F215-F258 HydrophobicContact CD2-CG 4.3Å; F215-F258 AromaticContact CD2-CZ 3.52Å; F215-F258 HydrophobicContact CD2-CZ 3.52Å; F215-F258 HydrophobicContact CG-CE1 4.01Å; F215-F258 HydrophobicContact CG-CZ 4.08Å; I218-F258 HydrophobicContact CD1-CE2 4.09Å; I218-F258 HydrophobicContact CD1-CZ 4.16Å; I218-F258 HydrophobicContact CG2-CE2 4.43Å; V254-F258 HydrophobicContact CG1-CD2 3.82Å; V254-F258 HydrophobicContact CG1-CE2 3.86Å; V254-F258 WeakPolarHBondContact O-CD2 3.24Å; V254-F258 PolarHBondContact O-N 2.86Å; V254-F258 VanDerWaalsContact O-N 3.07Å; L255-F258 PolarHBondContact O-N 2.86Å; A256-F258 PolarHBondContact O-N 3.21Å; F258-C260 VanDerWaalsContact C-N 3.27Å; F258-C260 PolarHBondContact O-N 3.25Å; F258-F262 WeakPolarHBondContact O-CA 3.42Å; F258-F262 WeakPolarHBondContact O-CB 3.43Å; F258-F262 PolarHBondContact O-N 3.24Å
259	V	95.4	Very high	92.3	Very high	98 Å²	98	33 Å²	33	59%	0.594	18%	0.179	S	C	*	.	H	α-helix	trans	-59.8	-40.6	174.2	170	0	0	0	0	111	L255 A256 P263	L255-V259 WeakPolarHBondContact O-CB 3.3Å; L255-V259 VanDerWaalsContact O-CG2 3.29Å; L255-V259 WeakPolarHBondContact O-CG2 3.49Å; L255-V259 PolarHBondContact O-N 2.82Å; A256-V259 PolarHBondContact O-N 2.98Å; V259-P263 WeakPolarHBondContact O-CD 3.37Å
260	C	95.8	Very high	92.8	Very high	2 Å²	2	34.3 Å²	34.3	1%	0.014	19%	0.186	C	C	.	.	H	α-helix	trans	-73.3	-44.5	-177.1	-68.4	0	0	0	0	113.1	A256 F257 F258 L298 G299 N302	A256-C260 VanDerWaalsContact O-CB 3.26Å; A256-C260 WeakPolarHBondContact O-CB 3.4Å; A256-C260 PolarHBondContact O-N 3.47Å; A256-C260 PolarHBondContact O-SG 3.14Å; F257-C260 PolarHBondContact O-N 3.44Å; F258-C260 VanDerWaalsContact C-N 3.27Å; F258-C260 PolarHBondContact O-N 3.25Å; C260-L298 WeakPolarHBondContact CB-O 3.49Å; C260-G299 WeakPolarHBondContact O-CA 3.19Å; C260-G299 PolarHBondContact O-N 3.02Å; C260-N302 HydrophobicContact CB-CB 3.88Å
261	W	95.6	Very high	93.3	Very high	2 Å²	2	35 Å²	35	1%	0.008	19%	0.19	C	C	.	.	H	α-helix	trans	-97.5	-23.6	-169.5	-74.2	101.4	0	0	0	114.6	V119 F257 F264 H265 G299 F300	V119-W261 HydrophobicContact CG2-CH2 3.35Å; V119-W261 HydrophobicContact CG2-CZ2 3.84Å; V119-W261 HydrophobicContact CG2-CZ3 3.76Å; F257-W261 AromaticContact CD2-CD1 3.5Å; F257-W261 VanDerWaalsContact CD2-CD1 3.5Å; F257-W261 HydrophobicContact CD2-CG 4.47Å; F257-W261 AromaticContact CD2-NE1 3.96Å; F257-W261 HydrophobicContact CE1-CB 4.15Å; F257-W261 HydrophobicContact CE1-CG 4.36Å; F257-W261 AromaticContact CE2-CD1 3.33Å; F257-W261 HydrophobicContact CE2-CG 4.02Å; F257-W261 AromaticContact CE2-NE1 3.67Å; F257-W261 HydrophobicContact CZ-CB 4.17Å; F257-W261 AromaticContact CZ-CD1 3.69Å; F257-W261 AromaticContact CZ-CG 3.93Å; F257-W261 HydrophobicContact CZ-CG 3.93Å; F257-W261 WeakPolarHBondContact O-CB 3.49Å; F257-W261 PolarHBondContact O-N 3.46Å; W261-F264 HydrophobicContact CE3-CB 4.41Å; W261-F264 AromaticContact CE3-CD1 3.91Å; W261-F264 HydrophobicContact CE3-CD1 3.91Å; W261-F264 HydrophobicContact CE3-CG 4.34Å; W261-F264 HydrophobicContact CZ3-CD1 4.01Å; W261-F264 HydrophobicContact CZ3-CE1 4.37Å; W261-F264 HydrophobicContact CZ3-CG 4.4Å; W261-F264 PolarHBondContact O-N 2.85Å; W261-H265 PolarHBondContact O-CD2 3.31Å; W261-H265 PolarHBondContact O-N 2.79Å; W261-G299 VanDerWaalsContact CE2-O 3.32Å; W261-G299 VanDerWaalsContact CZ2-O 3.31Å; W261-G299 WeakPolarHBondContact CZ2-O 3.39Å; W261-G299 PolarHBondContact NE1-O 3.07Å; W261-F300 HydrophobicContact CH2-CD1 4.09Å; W261-F300 HydrophobicContact CH2-CE1 4.24Å
262	F	95.9	Very high	93.5	Very high	111 Å²	111	32.6 Å²	32.6	49%	0.487	18%	0.175	S	C	.	.	H	α-helix	trans	-55.6	-46.7	-178.8	175.3	-109.2	0	0	0	113.1	F211 F258 F264 H265 V266	F211-F262 AromaticContact CE1-CD2 3.91Å; F211-F262 HydrophobicContact CE1-CD2 3.91Å; F211-F262 HydrophobicContact CE1-CE2 4.44Å; F211-F262 HydrophobicContact CE2-CB 4.01Å; F211-F262 HydrophobicContact CE2-CD2 4.16Å; F211-F262 HydrophobicContact CZ-CB 4.02Å; F211-F262 AromaticContact CZ-CD2 3.4Å; F211-F262 HydrophobicContact CZ-CD2 3.4Å; F211-F262 HydrophobicContact CZ-CE2 4.3Å; F211-F262 HydrophobicContact CZ-CG 4.18Å; F258-F262 WeakPolarHBondContact O-CA 3.42Å; F258-F262 WeakPolarHBondContact O-CB 3.43Å; F258-F262 PolarHBondContact O-N 3.24Å; F262-F264 VanDerWaalsContact C-N 3.28Å; F262-F264 PolarHBondContact O-N 3.47Å; F262-H265 PolarHBondContact O-N 3.41Å; F262-V266 HydrophobicContact CD1-CG2 4.19Å; F262-V266 HydrophobicContact CD2-CG2 3.87Å; F262-V266 HydrophobicContact CE1-CG2 3.83Å; F262-V266 HydrophobicContact CE2-CG2 3.53Å; F262-V266 HydrophobicContact CG-CG2 4.23Å; F262-V266 HydrophobicContact CZ-CG2 3.51Å; F262-V266 WeakPolarHBondContact O-CG2 3.16Å; F262-V266 PolarHBondContact O-N 3.5Å
263	P	96.5	Very high	93.7	Very high	40 Å²	40	33.2 Å²	33.2	26%	0.26	18%	0.175	S	C	.	.	H	α-helix	trans	-60.8	-37.5	179.9	-26.1	38.6	0	0	0	112.8	V259 L267 T295 L298	V259-P263 WeakPolarHBondContact O-CD 3.37Å; P263-L267 WeakPolarHBondContact O-CG 3.14Å; P263-L267 PolarHBondContact O-N 3.03Å; P263-L267 VanDerWaalsContact O-N 3.1Å; P263-T295 HydrophobicContact CB-CG2 3.53Å; P263-L298 HydrophobicContact CG-CD2 3.91Å
264	F	95.4	Very high	93.9	Very high	22 Å²	22	34.6 Å²	34.6	10%	0.096	19%	0.185	C	C	.	.	H	α-helix	trans	-65.8	-44.7	176.8	172.2	-96.9	0	0	0	111.9	K206 W261 F262 L267 T268 L296	K206-F264 HydrophobicContact CD-CE1 4.35Å; W261-F264 HydrophobicContact CE3-CB 4.41Å; W261-F264 AromaticContact CE3-CD1 3.91Å; W261-F264 HydrophobicContact CE3-CD1 3.91Å; W261-F264 HydrophobicContact CE3-CG 4.34Å; W261-F264 HydrophobicContact CZ3-CD1 4.01Å; W261-F264 HydrophobicContact CZ3-CE1 4.37Å; W261-F264 HydrophobicContact CZ3-CG 4.4Å; W261-F264 PolarHBondContact O-N 2.85Å; F262-F264 VanDerWaalsContact C-N 3.28Å; F262-F264 PolarHBondContact O-N 3.47Å; F264-L267 PolarHBondContact O-N 2.9Å; F264-T268 WeakPolarHBondContact O-CB 3.14Å; F264-T268 PolarHBondContact O-N 2.88Å; F264-T268 PolarHBondContact O-OG1 3.35Å; F264-L296 HydrophobicContact CD2-CD1 4.03Å; F264-L296 HydrophobicContact CE2-CD1 3.82Å; F264-L296 HydrophobicContact CZ-CD1 4.48Å
265	H	95.8	Very high	93.8	Very high	3 Å²	3	37.4 Å²	37.4	1%	0.014	20%	0.202	C	C	.	.	H	α-helix	trans	-64.8	-43.3	178.2	-79.6	-64.9	0	0	0	112.2	N207 F211 W261 F262 L267 T268 F269	N207-H265 WeakPolarHBondContact OD1-CA 3.26Å; N207-H265 VanDerWaalsContact OD1-CB 3.26Å; N207-H265 WeakPolarHBondContact OD1-CB 3.03Å; N207-H265 PolarHBondContact OD1-ND1 3.09Å; N207-H265 PolarHBondContact OD1-O 3.28Å; F211-H265 HydrophobicContact CB-CB 4.38Å; F211-H265 HydrophobicContact CD2-CB 4.13Å; F211-H265 AromaticContact CD2-CD2 3.29Å; F211-H265 WeakPolarHBondContact CD2-CD2 3.41Å; F211-H265 AromaticContact CD2-CG 3.78Å; F211-H265 HydrophobicContact CG-CB 4.09Å; F211-H265 AromaticContact CG-CD2 3.76Å; F211-H265 AromaticContact CG-CG 3.83Å; W261-H265 PolarHBondContact O-CD2 3.31Å; W261-H265 PolarHBondContact O-N 2.79Å; F262-H265 PolarHBondContact O-N 3.41Å; H265-L267 PolarHBondContact O-N 3.35Å; H265-T268 PolarHBondContact O-N 3.4Å; H265-F269 WeakPolarHBondContact O-CB 3.44Å; H265-F269 PolarHBondContact O-N 3.44Å
266	V	96.3	Very high	93.7	Very high	53 Å²	53	35.8 Å²	35.8	32%	0.321	19%	0.194	S	C	.	.	H	α-helix	trans	-57.1	-51.8	174.5	171	0	0	0	0	110.9	F262 T268 F269 L270	F262-V266 HydrophobicContact CD1-CG2 4.19Å; F262-V266 HydrophobicContact CD2-CG2 3.87Å; F262-V266 HydrophobicContact CE1-CG2 3.83Å; F262-V266 HydrophobicContact CE2-CG2 3.53Å; F262-V266 HydrophobicContact CG-CG2 4.23Å; F262-V266 HydrophobicContact CZ-CG2 3.51Å; F262-V266 WeakPolarHBondContact O-CG2 3.16Å; F262-V266 PolarHBondContact O-N 3.5Å; V266-T268 VanDerWaalsContact C-N 3.33Å; V266-T268 PolarHBondContact O-N 2.92Å; V266-F269 WeakPolarHBondContact O-CB 3.48Å; V266-F269 PolarHBondContact O-N 3.48Å; V266-L270 HydrophobicContact CG1-CD1 4.04Å; V266-L270 HydrophobicContact CG1-CG 4.48Å; V266-L270 WeakPolarHBondContact O-CG 3.38Å; V266-L270 PolarHBondContact O-N 3.44Å
267	L	95.1	Very high	93.4	Very high	15 Å²	15	36.8 Å²	36.8	8%	0.079	21%	0.205	C	C	.	.	H	α-helix	trans	-65.2	-36.9	-179.8	-66.3	-178.1	0	0	0	112.4	P263 F264 H265 F269 L270 D271 I288 L291 M292 T295	P263-L267 WeakPolarHBondContact O-CG 3.14Å; P263-L267 PolarHBondContact O-N 3.03Å; P263-L267 VanDerWaalsContact O-N 3.1Å; F264-L267 PolarHBondContact O-N 2.9Å; H265-L267 PolarHBondContact O-N 3.35Å; L267-F269 VanDerWaalsContact C-N 3.33Å; L267-L270 HydrophobicContact CD2-CD1 4.41Å; L267-L270 PolarHBondContact O-N 3.26Å; L267-D271 WeakPolarHBondContact O-CB 3.43Å; L267-D271 PolarHBondContact O-N 2.78Å; L267-I288 HydrophobicContact CD2-CG1 4.48Å; L267-L291 HydrophobicContact CD1-CB 3.61Å; L267-M292 HydrophobicContact CB-CE 3.38Å; L267-M292 HydrophobicContact CD1-CB 4.47Å; L267-M292 HydrophobicContact CD1-CE 4.47Å; L267-T295 HydrophobicContact CD1-CG2 3.56Å; L267-T295 HydrophobicContact CG-CG2 4.45Å
268	T	94.4	Very high	93.3	Very high	10 Å²	10	41.7 Å²	41.7	6%	0.061	24%	0.235	C	C	.	.	H	α-helix	trans	-66.4	-36.2	176.4	-57.6	0	0	0	0	111.8	A203 F264 H265 V266 A272	A203-T268 HydrophobicContact CB-CG2 3.81Å; F264-T268 WeakPolarHBondContact O-CB 3.14Å; F264-T268 PolarHBondContact O-N 2.88Å; F264-T268 PolarHBondContact O-OG1 3.35Å; H265-T268 PolarHBondContact O-N 3.4Å; V266-T268 VanDerWaalsContact C-N 3.33Å; V266-T268 PolarHBondContact O-N 2.92Å; T268-A272 PolarHBondContact O-N 3.47Å; T268-A272 VanDerWaalsContact O-N 3.1Å
269	F	95.4	Very high	92.8	Very high	88 Å²	88	43.1 Å²	43.1	39%	0.386	24%	0.243	S	C	.	.	H	α-helix	trans	-67.2	-45.3	174.1	176.2	-103.3	0	0	0	111.4	L204 H265 V266 L267 D271 A272 L273	L204-F269 HydrophobicContact CD2-CD2 3.59Å; L204-F269 HydrophobicContact CD2-CE2 3.75Å; H265-F269 WeakPolarHBondContact O-CB 3.44Å; H265-F269 PolarHBondContact O-N 3.44Å; V266-F269 WeakPolarHBondContact O-CB 3.48Å; V266-F269 PolarHBondContact O-N 3.48Å; L267-F269 VanDerWaalsContact C-N 3.33Å; F269-D271 VanDerWaalsContact C-N 3.32Å; F269-D271 PolarHBondContact O-N 3.33Å; F269-A272 WeakPolarHBondContact O-CB 3.46Å; F269-A272 PolarHBondContact O-N 2.9Å; F269-L273 HydrophobicContact CD1-CD1 4.09Å; F269-L273 HydrophobicContact CD1-CG 4.48Å; F269-L273 HydrophobicContact CE1-CD1 3.44Å; F269-L273 VanDerWaalsContact CE1-CD1 3.44Å; F269-L273 HydrophobicContact CE1-CG 4.08Å; F269-L273 HydrophobicContact CE2-CD2 4.47Å; F269-L273 HydrophobicContact CE2-CG 4.43Å; F269-L273 HydrophobicContact CZ-CD1 3.69Å; F269-L273 HydrophobicContact CZ-CD2 4.22Å; F269-L273 HydrophobicContact CZ-CG 4.05Å; F269-L273 WeakPolarHBondContact O-CG 3.4Å; F269-L273 PolarHBondContact O-N 3.13Å
270	L	94.2	Very high	92	Very high	40 Å²	40	46.1 Å²	46.1	21%	0.209	25%	0.25	C	S	.	.	H	α-helix	trans	-61.8	-39.4	175.7	-67.5	174.5	0	0	0	112.1	V266 L267 A272 L273 S274 M279 V284 I288	V266-L270 HydrophobicContact CG1-CD1 4.04Å; V266-L270 HydrophobicContact CG1-CG 4.48Å; V266-L270 WeakPolarHBondContact O-CG 3.38Å; V266-L270 PolarHBondContact O-N 3.44Å; L267-L270 HydrophobicContact CD2-CD1 4.41Å; L267-L270 PolarHBondContact O-N 3.26Å; L270-A272 VanDerWaalsContact C-N 3.35Å; L270-L273 PolarHBondContact O-N 3.49Å; L270-S274 WeakPolarHBondContact O-CB 3.49Å; L270-S274 PolarHBondContact O-N 2.84Å; L270-M279 HydrophobicContact CD2-CE 3.94Å; L270-M279 HydrophobicContact CD2-SD 4.14Å; L270-V284 HydrophobicContact CB-CG1 4.14Å; L270-V284 HydrophobicContact CD1-CG1 4.39Å; L270-I288 HydrophobicContact CB-CD1 4.18Å
271	D	91.6	Very high	91.5	Very high	17 Å²	17	48.5 Å²	48.5	9%	0.091	27%	0.267	C	S	.	.	H	α-helix	trans	-63.8	-39.9	176.1	-161.2	14	0	0	0	111.8	S3 F199 L267 F269 S274 T275 I288	S3-D271 WeakPolarHBondContact CB-OD2 3.49Å; S3-D271 PolarHBondContact OG-OD2 3.45Å; F199-D271 HydrophobicContact CE1-CB 4.41Å; F199-D271 HydrophobicContact CZ-CB 4.28Å; F199-D271 VanDerWaalsContact CZ-OD2 3.28Å; F199-D271 WeakPolarHBondContact CZ-OD2 3.28Å; L267-D271 WeakPolarHBondContact O-CB 3.43Å; L267-D271 PolarHBondContact O-N 2.78Å; F269-D271 VanDerWaalsContact C-N 3.32Å; F269-D271 PolarHBondContact O-N 3.33Å; D271-S274 PolarHBondContact O-N 3.28Å; D271-T275 WeakPolarHBondContact O-CB 3.31Å; D271-T275 PolarHBondContact O-N 3.01Å; D271-T275 PolarHBondContact O-OG1 3.45Å; D271-I288 HydrophobicContact CB-CD1 4.01Å; D271-I288 HydrophobicContact CB-CG1 4.48Å; D271-I288 HydrophobicContact CB-CG2 4.1Å
272	A	92.6	Very high	91	Very high	0 Å²	0	51 Å²	51	0%	0	28%	0.284	C	S	.	.	H	α-helix	trans	-63.9	-44.5	173.2	0	0	0	0	0	112.2	P200 A203 L204 T268 F269 L270 T275 L276	P200-A272 HydrophobicContact CB-CB 4.05Å; A203-A272 HydrophobicContact CB-CB 3.98Å; L204-A272 HydrophobicContact CD2-CB 4.16Å; L204-A272 HydrophobicContact CG-CB 4.06Å; T268-A272 PolarHBondContact O-N 3.47Å; T268-A272 VanDerWaalsContact O-N 3.1Å; F269-A272 WeakPolarHBondContact O-CB 3.46Å; F269-A272 PolarHBondContact O-N 2.9Å; L270-A272 VanDerWaalsContact C-N 3.35Å; A272-T275 PolarHBondContact O-N 2.88Å; A272-L276 WeakPolarHBondContact O-CG 3.47Å; A272-L276 PolarHBondContact O-N 2.9Å
273	L	92.5	Very high	90.5	Very high	34 Å²	34	55.2 Å²	55.2	18%	0.178	30%	0.297	C	S	.	.	H	α-helix	trans	-64.9	-38.9	176.9	-69.2	-173.6	0	0	0	112.6	F269 L270 L276 G277 V278 M279	F269-L273 HydrophobicContact CD1-CD1 4.09Å; F269-L273 HydrophobicContact CD1-CG 4.48Å; F269-L273 HydrophobicContact CE1-CD1 3.44Å; F269-L273 VanDerWaalsContact CE1-CD1 3.44Å; F269-L273 HydrophobicContact CE1-CG 4.08Å; F269-L273 HydrophobicContact CE2-CD2 4.47Å; F269-L273 HydrophobicContact CE2-CG 4.43Å; F269-L273 HydrophobicContact CZ-CD1 3.69Å; F269-L273 HydrophobicContact CZ-CD2 4.22Å; F269-L273 HydrophobicContact CZ-CG 4.05Å; F269-L273 WeakPolarHBondContact O-CG 3.4Å; F269-L273 PolarHBondContact O-N 3.13Å; L270-L273 PolarHBondContact O-N 3.49Å; L273-L276 PolarHBondContact O-N 3.01Å; L273-G277 PolarHBondContact O-N 3.08Å; L273-V278 HydrophobicContact CB-CB 4.46Å; L273-V278 HydrophobicContact CD2-CB 4.46Å; L273-V278 PolarHBondContact O-N 3.17Å; L273-M279 HydrophobicContact CD1-CE 4.36Å
274	S	90.4	Very high	90	Very high	31 Å²	31	54.1 Å²	54.1	22%	0.217	29%	0.289	C	S	.	.	H	α-helix	trans	-65.5	-42	176.4	-169.6	0	0	0	0	111.2	L270 D271 L276 G277 M279	L270-S274 WeakPolarHBondContact O-CB 3.49Å; L270-S274 PolarHBondContact O-N 2.84Å; D271-S274 PolarHBondContact O-N 3.28Å; S274-L276 VanDerWaalsContact C-N 3.29Å; S274-L276 PolarHBondContact O-N 3.29Å; S274-G277 PolarHBondContact O-N 3.02Å; S274-G277 VanDerWaalsContact O-N 3.12Å; S274-M279 WeakPolarHBondContact CA-O 3.27Å; S274-M279 PolarHBondContact OG-O 3.19Å
275	T	87.8	Confident	89.5	Confident	71 Å²	71	57.9 Å²	57.9	44%	0.436	30%	0.303	S	S	.	.	H	α-helix	trans	-64.2	-33.6	175.9	-55.6	0	0	0	0	112.5	F199 P200 D271 A272 G277	F199-T275 HydrophobicContact CD1-CG2 4.08Å; F199-T275 WeakPolarHBondContact CE1-OG1 3.34Å; P200-T275 HydrophobicContact CG-CG2 4.34Å; D271-T275 WeakPolarHBondContact O-CB 3.31Å; D271-T275 PolarHBondContact O-N 3.01Å; D271-T275 PolarHBondContact O-OG1 3.45Å; A272-T275 PolarHBondContact O-N 2.88Å; T275-G277 PolarHBondContact O-N 3.27Å
276	L	90.1	Very high	89.1	Confident	73 Å²	73	59.8 Å²	59.8	38%	0.382	31%	0.312	S	S	.	.	T	Hydrogen-bonded Turn	trans	-77.9	-0.8	176.4	-71.6	171	0	0	0	113.9	Y197 P200 L204 A272 L273 S274 V278	Y197-L276 HydrophobicContact CD1-CD2 4.22Å; P200-L276 HydrophobicContact CB-CD1 4.03Å; P200-L276 HydrophobicContact CB-CD2 4.04Å; P200-L276 HydrophobicContact CB-CG 3.76Å; P200-L276 HydrophobicContact CG-CD2 3.83Å; P200-L276 HydrophobicContact CG-CG 4.07Å; L204-L276 HydrophobicContact CD1-CD1 4.3Å; A272-L276 WeakPolarHBondContact O-CG 3.47Å; A272-L276 PolarHBondContact O-N 2.9Å; L273-L276 PolarHBondContact O-N 3.01Å; S274-L276 VanDerWaalsContact C-N 3.29Å; S274-L276 PolarHBondContact O-N 3.29Å; L276-V278 HydrophobicContact CB-CG2 4.09Å; L276-V278 PolarHBondContact O-N 3.28Å
277	G	87	Confident	88.6	Confident	35 Å²	35	58.2 Å²	58.2	36%	0.361	31%	0.305	S	S	.	.	T	Hydrogen-bonded Turn	trans	70.5	16.4	-177.7	0	0	0	0	0	114.2	L273 S274 T275 M279 H280	L273-G277 PolarHBondContact O-N 3.08Å; S274-G277 PolarHBondContact O-N 3.02Å; S274-G277 VanDerWaalsContact O-N 3.12Å; T275-G277 PolarHBondContact O-N 3.27Å; G277-M279 VanDerWaalsContact C-N 3.35Å; G277-H280 PolarHBondContact O-NE2 3.05Å; G277-H280 VanDerWaalsContact O-NE2 3.07Å
278	V	89.3	Confident	88.3	Confident	104 Å²	104	57.8 Å²	57.8	63%	0.63	30%	0.302	S	S	*	.	S	Bend	trans	-78.8	-26.2	175.7	180	0	0	0	0	110.7	L273 L276	L273-V278 HydrophobicContact CB-CB 4.46Å; L273-V278 HydrophobicContact CD2-CB 4.46Å; L273-V278 PolarHBondContact O-N 3.17Å; L276-V278 HydrophobicContact CB-CG2 4.09Å; L276-V278 PolarHBondContact O-N 3.28Å
279	M	82.4	Confident	87.7	Confident	57 Å²	57	59.6 Å²	59.6	28%	0.281	31%	0.311	S	S	.	.			trans	-137.6	121.7	-175	-171.4	-179.7	-65	0	0	111.8	L270 L273 S274 G277 V284	L270-M279 HydrophobicContact CD2-CE 3.94Å; L270-M279 HydrophobicContact CD2-SD 4.14Å; L273-M279 HydrophobicContact CD1-CE 4.36Å; S274-M279 WeakPolarHBondContact CA-O 3.27Å; S274-M279 PolarHBondContact OG-O 3.19Å; G277-M279 VanDerWaalsContact C-N 3.35Å; M279-V284 HydrophobicContact SD-CB 4.12Å; M279-V284 HydrophobicContact SD-CG1 3.77Å; M279-V284 HydrophobicContact SD-CG2 3.75Å
280	H	78.3	Confident	87.2	Confident	160 Å²	160	58 Å²	58	74%	0.741	31%	0.308	S	S	*	.			trans	-116.3	27	-174.5	-67.2	-66.9	0	0	0	114.6	G277	G277-H280 PolarHBondContact O-NE2 3.05Å; G277-H280 VanDerWaalsContact O-NE2 3.07Å
281	S	84.6	Confident	87	Confident	52 Å²	52	60 Å²	60	36%	0.364	32%	0.319	S	S	.	.			trans	-81.8	120.7	-179.7	177	0	0	0	0	112.2	W283 V284 R285	S281-W283 PolarHBondContact O-N 3.2Å; S281-W283 PolarHBondContact OG-N 3.28Å; S281-V284 PolarHBondContact O-N 3.21Å; S281-V284 VanDerWaalsContact O-N 3.12Å; S281-R285 PolarHBondContact O-N 3.45Å; S281-R285 VanDerWaalsContact O-N 3.13Å
282	C	84.8	Confident	86.9	Confident	55 Å²	55	59.9 Å²	59.9	37%	0.372	32%	0.318	S	S	.	.	H	α-helix	trans	-56.6	-35.8	172.4	-76.9	0	0	0	0	112.2	C25 V284 R285 Q286	C25-C282 HydrophobicContact CB-CB 3.85Å; C25-C282 WeakPolarHBondContact CB-SG 3.4Å; C25-C282 WeakPolarHBondContact SG-CA 3.34Å; C25-C282 WeakPolarHBondContact SG-CB 3.45Å; C25-C282 CovalentContact SG-SG 2.05Å; C25-C282 PolarHBondContact SG-SG 3.35Å; C282-V284 VanDerWaalsContact C-N 3.33Å; C282-V284 PolarHBondContact O-N 2.9Å; C282-R285 PolarHBondContact O-N 2.79Å; C282-Q286 WeakPolarHBondContact O-CB 2.97Å; C282-Q286 PolarHBondContact O-N 3.45Å
283	W	85.8	Confident	86.7	Confident	200 Å²	200	59.9 Å²	59.9	76%	0.758	32%	0.318	S	S	*	.	H	α-helix	trans	-63.1	-40.5	177.8	-178.1	80	0	0	0	111.9	S281 Q286 A287	S281-W283 PolarHBondContact O-N 3.2Å; S281-W283 PolarHBondContact OG-N 3.28Å; W283-Q286 PolarHBondContact O-N 3.4Å; W283-A287 WeakPolarHBondContact O-CB 3.47Å; W283-A287 PolarHBondContact O-N 3.09Å
284	V	86.3	Confident	86.7	Confident	16 Å²	16	61.5 Å²	61.5	10%	0.097	32%	0.324	C	S	.	.	H	α-helix	trans	-66.4	-45.4	177.2	174.4	0	0	0	0	110.7	L270 M279 S281 C282 Q286 A287 I288	L270-V284 HydrophobicContact CB-CG1 4.14Å; L270-V284 HydrophobicContact CD1-CG1 4.39Å; M279-V284 HydrophobicContact SD-CB 4.12Å; M279-V284 HydrophobicContact SD-CG1 3.77Å; M279-V284 HydrophobicContact SD-CG2 3.75Å; S281-V284 PolarHBondContact O-N 3.21Å; S281-V284 VanDerWaalsContact O-N 3.12Å; C282-V284 VanDerWaalsContact C-N 3.33Å; C282-V284 PolarHBondContact O-N 2.9Å; V284-Q286 VanDerWaalsContact C-N 3.3Å; V284-Q286 PolarHBondContact O-N 3.35Å; V284-A287 PolarHBondContact O-N 3.34Å; V284-I288 HydrophobicContact CG1-CD1 3.84Å; V284-I288 HydrophobicContact CG1-CG1 4.47Å; V284-I288 WeakPolarHBondContact O-CD1 3.5Å; V284-I288 VanDerWaalsContact O-CG1 3.29Å; V284-I288 WeakPolarHBondContact O-CG1 2.94Å; V284-I288 PolarHBondContact O-N 2.91Å
285	R	85.6	Confident	86.9	Confident	101 Å²	101	60.7 Å²	60.7	38%	0.381	32%	0.318	S	S	.	.	H	α-helix	trans	-60	-42.4	176.4	-170.5	169	-178.5	-129	-2.4	111.6	S281 C282 I288 I289	S281-R285 PolarHBondContact O-N 3.45Å; S281-R285 VanDerWaalsContact O-N 3.13Å; C282-R285 PolarHBondContact O-N 2.79Å; R285-I288 PolarHBondContact O-N 3.38Å; R285-I289 HydrophobicContact CG-CD1 4.25Å; R285-I289 WeakPolarHBondContact O-CG1 3.42Å; R285-I289 PolarHBondContact O-N 2.96Å; R285-I289 VanDerWaalsContact O-N 3.08Å
286	Q	85.8	Confident	87.1	Confident	43 Å²	43	58.7 Å²	58.7	20%	0.201	30%	0.304	C	S	.	.	H	α-helix	trans	-64.9	-42.2	176.7	-172	58.5	28.4	0	0	112.2	C282 W283 V284 I289 T290	C282-Q286 WeakPolarHBondContact O-CB 2.97Å; C282-Q286 PolarHBondContact O-N 3.45Å; W283-Q286 PolarHBondContact O-N 3.4Å; V284-Q286 VanDerWaalsContact C-N 3.3Å; V284-Q286 PolarHBondContact O-N 3.35Å; Q286-I289 PolarHBondContact O-N 3.46Å; Q286-T290 PolarHBondContact NE2-OG1 2.85Å; Q286-T290 VanDerWaalsContact NE2-OG1 3.1Å; Q286-T290 VanDerWaalsContact O-CB 3.3Å; Q286-T290 WeakPolarHBondContact O-CB 3.16Å; Q286-T290 PolarHBondContact O-N 3.12Å; Q286-T290 PolarHBondContact O-OG1 2.84Å
287	A	87.3	Confident	87.3	Confident	21 Å²	21	55.4 Å²	55.4	17%	0.174	29%	0.287	C	S	.	.	H	α-helix	trans	-61.7	-42.6	175.6	0	0	0	0	0	111.5	W283 V284 T290 L291	W283-A287 WeakPolarHBondContact O-CB 3.47Å; W283-A287 PolarHBondContact O-N 3.09Å; V284-A287 PolarHBondContact O-N 3.34Å; A287-T290 PolarHBondContact O-N 3.36Å; A287-L291 HydrophobicContact CB-CD1 4.32Å; A287-L291 WeakPolarHBondContact O-CB 3.29Å; A287-L291 WeakPolarHBondContact O-CG 3.13Å; A287-L291 PolarHBondContact O-N 2.84Å
288	I	87.9	Confident	87.8	Confident	6 Å²	6	56.9 Å²	56.9	3%	0.031	29%	0.286	C	S	.	.	H	α-helix	trans	-59.1	-51.8	176.1	-69.2	159.7	0	0	0	110.5	L267 L270 D271 V284 R285 T290 M292	L267-I288 HydrophobicContact CD2-CG1 4.48Å; L270-I288 HydrophobicContact CB-CD1 4.18Å; D271-I288 HydrophobicContact CB-CD1 4.01Å; D271-I288 HydrophobicContact CB-CG1 4.48Å; D271-I288 HydrophobicContact CB-CG2 4.1Å; V284-I288 HydrophobicContact CG1-CD1 3.84Å; V284-I288 HydrophobicContact CG1-CG1 4.47Å; V284-I288 WeakPolarHBondContact O-CD1 3.5Å; V284-I288 VanDerWaalsContact O-CG1 3.29Å; V284-I288 WeakPolarHBondContact O-CG1 2.94Å; V284-I288 PolarHBondContact O-N 2.91Å; R285-I288 PolarHBondContact O-N 3.38Å; I288-T290 VanDerWaalsContact C-N 3.34Å; I288-T290 PolarHBondContact O-N 2.8Å; I288-M292 HydrophobicContact CG2-CE 4.4Å; I288-M292 WeakPolarHBondContact O-CB 3.49Å; I288-M292 PolarHBondContact O-N 2.75Å; I288-M292 VanDerWaalsContact O-N 3.13Å
289	I	83.1	Confident	88.1	Confident	47 Å²	47	51.9 Å²	51.9	24%	0.241	26%	0.256	C	S	.	.	H	α-helix	trans	-61.9	-43.7	-177.9	-66.5	171.5	0	0	0	111	T4 R285 Q286	T4-I289 HydrophobicContact CG2-CD1 4.03Å; T4-I289 HydrophobicContact CG2-CG1 3.84Å; T4-I289 HydrophobicContact CG2-CG2 4.19Å; R285-I289 HydrophobicContact CG-CD1 4.25Å; R285-I289 WeakPolarHBondContact O-CG1 3.42Å; R285-I289 PolarHBondContact O-N 2.96Å; R285-I289 VanDerWaalsContact O-N 3.08Å; Q286-I289 PolarHBondContact O-N 3.46Å
290	T	84.3	Confident	88.7	Confident	54 Å²	54	49.3 Å²	49.3	33%	0.331	24%	0.243	S	C	.	.	H	α-helix	trans	-77.1	-44.7	-173.4	-52.1	0	0	0	0	112.4	Q286 A287 I288 F294	Q286-T290 PolarHBondContact NE2-OG1 2.85Å; Q286-T290 VanDerWaalsContact NE2-OG1 3.1Å; Q286-T290 VanDerWaalsContact O-CB 3.3Å; Q286-T290 WeakPolarHBondContact O-CB 3.16Å; Q286-T290 PolarHBondContact O-N 3.12Å; Q286-T290 PolarHBondContact O-OG1 2.84Å; A287-T290 PolarHBondContact O-N 3.36Å; I288-T290 VanDerWaalsContact C-N 3.34Å; I288-T290 PolarHBondContact O-N 2.8Å; T290-F294 VanDerWaalsContact O-CD2 3.27Å; T290-F294 WeakPolarHBondContact O-CD2 3.49Å; T290-F294 WeakPolarHBondContact O-CE2 3.32Å
291	L	90	Very high	89.5	Confident	84 Å²	84	43 Å²	43	44%	0.44	22%	0.217	S	C	.	.	H	α-helix	trans	-91.8	-24.7	-168.8	-61.1	177.4	0	0	0	113.5	L267 A287 P293 F294 T295	L267-L291 HydrophobicContact CD1-CB 3.61Å; A287-L291 HydrophobicContact CB-CD1 4.32Å; A287-L291 WeakPolarHBondContact O-CB 3.29Å; A287-L291 WeakPolarHBondContact O-CG 3.13Å; A287-L291 PolarHBondContact O-N 2.84Å; L291-P293 VanDerWaalsContact C-CD 3.41Å; L291-F294 PolarHBondContact O-N 2.97Å; L291-T295 WeakPolarHBondContact O-CG2 3.3Å; L291-T295 PolarHBondContact O-N 3.33Å
292	M	89.6	Confident	90	Very high	13 Å²	13	40.5 Å²	40.5	6%	0.064	20%	0.2	C	C	.	.	H	α-helix	trans	-55.5	-39.8	-175.3	-174.8	145.7	-68.9	0	0	115.1	L267 I288 F294 T295 L296	L267-M292 HydrophobicContact CB-CE 3.38Å; L267-M292 HydrophobicContact CD1-CB 4.47Å; L267-M292 HydrophobicContact CD1-CE 4.47Å; I288-M292 HydrophobicContact CG2-CE 4.4Å; I288-M292 WeakPolarHBondContact O-CB 3.49Å; I288-M292 PolarHBondContact O-N 2.75Å; I288-M292 VanDerWaalsContact O-N 3.13Å; M292-F294 VanDerWaalsContact C-N 3.3Å; M292-F294 PolarHBondContact O-N 2.85Å; M292-T295 WeakPolarHBondContact CA-OG1 3.32Å; M292-T295 PolarHBondContact O-OG1 3.16Å; M292-T295 VanDerWaalsContact O-OG1 3.08Å; M292-L296 WeakPolarHBondContact O-CB 3.49Å; M292-L296 PolarHBondContact O-N 3.32Å
293	P	88.5	Confident	90.5	Very high	1 Å²	1	37.9 Å²	37.9	1%	0.006	18%	0.182	C	C	.	.	H	α-helix	trans	-65	-36.7	176.7	-19.8	33.9	0	0	0	112	M1 I38 L291 L296 C297	M1-P293 HydrophobicContact CE-CB 4.08Å; M1-P293 HydrophobicContact CE-CG 3.28Å; M1-P293 HydrophobicContact CG-CG 4.39Å; M1-P293 HydrophobicContact SD-CB 4.12Å; M1-P293 HydrophobicContact SD-CG 3.68Å; I38-P293 HydrophobicContact CD1-CB 3.63Å; L291-P293 VanDerWaalsContact C-CD 3.41Å; P293-L296 WeakPolarHBondContact O-CB 3.04Å; P293-L296 PolarHBondContact O-N 2.85Å; P293-C297 PolarHBondContact O-N 3.41Å; P293-C297 PolarHBondContact O-SG 3.14Å
294	F	91.1	Very high	91	Very high	68 Å²	68	28.7 Å²	28.7	30%	0.298	15%	0.149	S	C	.	.	H	α-helix	trans	-74.3	-39.6	178.9	-62.1	-71.3	0	0	0	112.4	Q34 L37 T290 L291 M292 L296 C297 L298	Q34-F294 HydrophobicContact CG-CZ 4.16Å; L37-F294 HydrophobicContact CD2-CE1 3.81Å; L37-F294 HydrophobicContact CD2-CZ 4.48Å; T290-F294 VanDerWaalsContact O-CD2 3.27Å; T290-F294 WeakPolarHBondContact O-CD2 3.49Å; T290-F294 WeakPolarHBondContact O-CE2 3.32Å; L291-F294 PolarHBondContact O-N 2.97Å; M292-F294 VanDerWaalsContact C-N 3.3Å; M292-F294 PolarHBondContact O-N 2.85Å; F294-L296 PolarHBondContact O-N 3.4Å; F294-C297 WeakPolarHBondContact O-CB 3.46Å; F294-C297 PolarHBondContact O-N 3.3Å; F294-L298 PolarHBondContact O-N 3.01Å
295	T	94.6	Very high	91.3	Very high	14 Å²	14	30.6 Å²	30.6	9%	0.086	16%	0.158	C	C	.	.	H	α-helix	trans	-66.4	-29.7	173.5	62.7	0	0	0	0	111.7	P263 L267 L291 M292 L298 G299	P263-T295 HydrophobicContact CB-CG2 3.53Å; L267-T295 HydrophobicContact CD1-CG2 3.56Å; L267-T295 HydrophobicContact CG-CG2 4.45Å; L291-T295 WeakPolarHBondContact O-CG2 3.3Å; L291-T295 PolarHBondContact O-N 3.33Å; M292-T295 WeakPolarHBondContact CA-OG1 3.32Å; M292-T295 PolarHBondContact O-OG1 3.16Å; M292-T295 VanDerWaalsContact O-OG1 3.08Å; T295-L298 PolarHBondContact O-N 2.73Å; T295-G299 PolarHBondContact O-N 3.36Å
296	L	92.8	Very high	91.5	Very high	28 Å²	28	25.8 Å²	25.8	15%	0.147	14%	0.14	C	C	.	.	H	α-helix	trans	-68.1	-44.2	171	-167.9	69	0	0	0	111.8	F264 M292 P293 F294 L298 G299 F300	F264-L296 HydrophobicContact CD2-CD1 4.03Å; F264-L296 HydrophobicContact CE2-CD1 3.82Å; F264-L296 HydrophobicContact CZ-CD1 4.48Å; M292-L296 WeakPolarHBondContact O-CB 3.49Å; M292-L296 PolarHBondContact O-N 3.32Å; P293-L296 WeakPolarHBondContact O-CB 3.04Å; P293-L296 PolarHBondContact O-N 2.85Å; F294-L296 PolarHBondContact O-N 3.4Å; L296-L298 VanDerWaalsContact C-N 3.26Å; L296-L298 PolarHBondContact O-N 3.34Å; L296-G299 PolarHBondContact O-N 3.07Å; L296-F300 HydrophobicContact CD1-CD1 4.23Å; L296-F300 HydrophobicContact CD1-CE1 3.34Å; L296-F300 HydrophobicContact CD1-CE2 4.43Å; L296-F300 HydrophobicContact CD1-CZ 3.51Å; L296-F300 HydrophobicContact CD2-CE1 4.35Å; L296-F300 HydrophobicContact CD2-CE2 4.01Å; L296-F300 HydrophobicContact CD2-CZ 3.64Å; L296-F300 HydrophobicContact CG-CD1 4.29Å; L296-F300 HydrophobicContact CG-CD2 4.42Å; L296-F300 HydrophobicContact CG-CE1 3.58Å; L296-F300 HydrophobicContact CG-CE2 3.8Å; L296-F300 HydrophobicContact CG-CZ 3.33Å; L296-F300 VanDerWaalsContact O-CD1 3.31Å; L296-F300 WeakPolarHBondContact O-CD1 3.45Å; L296-F300 WeakPolarHBondContact O-CG 3.18Å; L296-F300 PolarHBondContact O-N 2.87Å
297	C	95.1	Very high	91.5	Very high	5 Å²	5	24 Å²	24	3%	0.034	13%	0.132	C	C	.	.	H	α-helix	trans	-55.9	-43.3	172	-66.6	0	0	0	0	111.8	I41 Y42 P293 F294 F300 S301	I41-C297 HydrophobicContact CG2-CB 3.95Å; Y42-C297 HydrophobicContact CE1-CB 4.31Å; Y42-C297 WeakPolarHBondContact CE1-SG 3.48Å; P293-C297 PolarHBondContact O-N 3.41Å; P293-C297 PolarHBondContact O-SG 3.14Å; F294-C297 WeakPolarHBondContact O-CB 3.46Å; F294-C297 PolarHBondContact O-N 3.3Å; C297-F300 PolarHBondContact O-N 2.84Å; C297-S301 PolarHBondContact O-N 3.45Å; C297-S301 PolarHBondContact O-OG 2.99Å
298	L	96.4	Very high	91.3	Very high	65 Å²	65	27 Å²	27	34%	0.34	14%	0.142	S	C	.	.	H	α-helix	trans	-64.7	-45.2	176.9	-175.7	64.8	0	0	0	111.4	C260 P263 F294 T295 L296 F300 S301	C260-L298 WeakPolarHBondContact CB-O 3.49Å; P263-L298 HydrophobicContact CG-CD2 3.91Å; F294-L298 PolarHBondContact O-N 3.01Å; T295-L298 PolarHBondContact O-N 2.73Å; L296-L298 VanDerWaalsContact C-N 3.26Å; L296-L298 PolarHBondContact O-N 3.34Å; L298-F300 VanDerWaalsContact C-N 3.32Å; L298-F300 PolarHBondContact O-N 2.03Å; L298-S301 VanDerWaalsContact O-CB 3.29Å; L298-S301 WeakPolarHBondContact O-CB 2.96Å; L298-S301 PolarHBondContact O-N 3.46Å; L298-S301 VanDerWaalsContact O-N 3.14Å
299	G	95.4	Very high	91.2	Very high	0 Å²	0	28.1 Å²	28.1	0%	0	15%	0.147	C	C	.	.	H	α-helix	trans	-56.4	-44.7	173.6	0	0	0	0	0	112.5	C260 W261 T295 L296 S301 N302	C260-G299 WeakPolarHBondContact O-CA 3.19Å; C260-G299 PolarHBondContact O-N 3.02Å; W261-G299 VanDerWaalsContact CE2-O 3.32Å; W261-G299 VanDerWaalsContact CZ2-O 3.31Å; W261-G299 WeakPolarHBondContact CZ2-O 3.39Å; W261-G299 PolarHBondContact NE1-O 3.07Å; T295-G299 PolarHBondContact O-N 3.36Å; L296-G299 PolarHBondContact O-N 3.07Å; G299-S301 VanDerWaalsContact C-N 3.27Å; G299-S301 PolarHBondContact O-N 2.92Å; G299-N302 WeakPolarHBondContact O-CB 3.32Å; G299-N302 PolarHBondContact O-N 3.22Å; G299-N302 VanDerWaalsContact O-N 3.16Å
300	F	95.1	Very high	91	Very high	2 Å²	2	26.1 Å²	26.1	1%	0.009	14%	0.137	C	C	.	.	H	α-helix	trans	-67.3	-28.7	179.1	-65.8	-2.8	0	0	0	112.9	Y42 I45 F84 L88 L115 W261 L296 C297 L298 N302 S303	Y42-F300 HydrophobicContact CD1-CD2 4.14Å; Y42-F300 AromaticContact CE1-CD2 3.48Å; Y42-F300 HydrophobicContact CE1-CD2 3.48Å; Y42-F300 VanDerWaalsContact CE1-CD2 3.48Å; Y42-F300 AromaticContact CE1-CE2 3.88Å; Y42-F300 HydrophobicContact CE1-CE2 3.88Å; Y42-F300 HydrophobicContact CE2-CE2 4.27Å; Y42-F300 AromaticContact CZ-CD2 3.74Å; Y42-F300 AromaticContact CZ-CE2 3.62Å; Y42-F300 WeakPolarHBondContact OH-CE2 3.27Å; I45-F300 HydrophobicContact CD1-CB 3.96Å; I45-F300 WeakPolarHBondContact CG2-O 3.23Å; F84-F300 HydrophobicContact CE1-CB 4.18Å; F84-F300 HydrophobicContact CE1-CD1 4.47Å; F84-F300 HydrophobicContact CE1-CG 4.29Å; F84-F300 HydrophobicContact CE2-CD1 4.11Å; F84-F300 HydrophobicContact CE2-CD2 4.31Å; F84-F300 HydrophobicContact CE2-CE1 4.15Å; F84-F300 HydrophobicContact CE2-CE2 4.29Å; F84-F300 HydrophobicContact CE2-CG 4.21Å; F84-F300 HydrophobicContact CE2-CZ 4.2Å; F84-F300 HydrophobicContact CZ-CB 3.77Å; F84-F300 AromaticContact CZ-CD1 3.63Å; F84-F300 HydrophobicContact CZ-CD1 3.63Å; F84-F300 AromaticContact CZ-CD2 3.78Å; F84-F300 HydrophobicContact CZ-CD2 3.78Å; F84-F300 HydrophobicContact CZ-CE1 4.14Å; F84-F300 HydrophobicContact CZ-CE2 4.21Å; F84-F300 AromaticContact CZ-CG 3.44Å; F84-F300 HydrophobicContact CZ-CG 3.44Å; F84-F300 VanDerWaalsContact CZ-CG 3.44Å; F84-F300 HydrophobicContact CZ-CZ 4.38Å; L88-F300 HydrophobicContact CD1-CD2 3.69Å; L88-F300 HydrophobicContact CD1-CE2 4.01Å; L115-F300 HydrophobicContact CD1-CD1 4.06Å; L115-F300 HydrophobicContact CD1-CE1 3.21Å; L115-F300 HydrophobicContact CD1-CZ 3.69Å; L115-F300 HydrophobicContact CD2-CE1 4.06Å; L115-F300 HydrophobicContact CD2-CZ 3.77Å; L115-F300 HydrophobicContact CG-CE1 4.27Å; L115-F300 HydrophobicContact CG-CZ 4.37Å; W261-F300 HydrophobicContact CH2-CD1 4.09Å; W261-F300 HydrophobicContact CH2-CE1 4.24Å; L296-F300 HydrophobicContact CD1-CD1 4.23Å; L296-F300 HydrophobicContact CD1-CE1 3.34Å; L296-F300 HydrophobicContact CD1-CE2 4.43Å; L296-F300 HydrophobicContact CD1-CZ 3.51Å; L296-F300 HydrophobicContact CD2-CE1 4.35Å; L296-F300 HydrophobicContact CD2-CE2 4.01Å; L296-F300 HydrophobicContact CD2-CZ 3.64Å; L296-F300 HydrophobicContact CG-CD1 4.29Å; L296-F300 HydrophobicContact CG-CD2 4.42Å; L296-F300 HydrophobicContact CG-CE1 3.58Å; L296-F300 HydrophobicContact CG-CE2 3.8Å; L296-F300 HydrophobicContact CG-CZ 3.33Å; L296-F300 VanDerWaalsContact O-CD1 3.31Å; L296-F300 WeakPolarHBondContact O-CD1 3.45Å; L296-F300 WeakPolarHBondContact O-CG 3.18Å; L296-F300 PolarHBondContact O-N 2.87Å; C297-F300 PolarHBondContact O-N 2.84Å; L298-F300 VanDerWaalsContact C-N 3.32Å; L298-F300 PolarHBondContact O-N 2.03Å; F300-N302 PolarHBondContact O-N 2.93Å; F300-S303 PolarHBondContact O-N 2.81Å
301	S	96.4	Very high	90.3	Very high	27 Å²	27	24.9 Å²	24.9	19%	0.189	13%	0.13	C	C	.	.	H	α-helix	trans	-61.7	-23.1	175.8	-58.5	0	0	0	0	112.1	I45 C297 L298 G299 S303 A304 I305	I45-S301 WeakPolarHBondContact CD1-OG 3.28Å; C297-S301 PolarHBondContact O-N 3.45Å; C297-S301 PolarHBondContact O-OG 2.99Å; L298-S301 VanDerWaalsContact O-CB 3.29Å; L298-S301 WeakPolarHBondContact O-CB 2.96Å; L298-S301 PolarHBondContact O-N 3.46Å; L298-S301 VanDerWaalsContact O-N 3.14Å; G299-S301 VanDerWaalsContact C-N 3.27Å; G299-S301 PolarHBondContact O-N 2.92Å; S301-S303 VanDerWaalsContact C-N 3.28Å; S301-S303 PolarHBondContact O-N 3.04Å; S301-A304 WeakPolarHBondContact O-CA 3.33Å; S301-A304 PolarHBondContact O-N 3.15Å; S301-I305 VanDerWaalsContact O-CG1 3.29Å; S301-I305 WeakPolarHBondContact O-CG1 3.35Å; S301-I305 PolarHBondContact O-N 3.47Å
302	N	95	Very high	89.1	Confident	0 Å²	0	28.1 Å²	28.1	0%	0	14%	0.14	C	C	.	.	H	α-helix	trans	-52	-44.7	174.2	-176.8	69.8	0	0	0	112.6	F257 C260 G299 F300 A304 I305 N306	F257-N302 VanDerWaalsContact CA-OD1 3.31Å; F257-N302 WeakPolarHBondContact CA-OD1 3.21Å; C260-N302 HydrophobicContact CB-CB 3.88Å; G299-N302 WeakPolarHBondContact O-CB 3.32Å; G299-N302 PolarHBondContact O-N 3.22Å; G299-N302 VanDerWaalsContact O-N 3.16Å; F300-N302 PolarHBondContact O-N 2.93Å; N302-A304 VanDerWaalsContact C-N 3.26Å; N302-A304 PolarHBondContact O-N 3.08Å; N302-I305 PolarHBondContact O-N 2.93Å; N302-N306 VanDerWaalsContact O-CG 3.32Å; N302-N306 PolarHBondContact O-N 3.2Å; N302-N306 VanDerWaalsContact O-N 3.16Å; N302-N306 PolarHBondContact O-ND2 3.17Å
303	S	95.1	Very high	87.7	Confident	0 Å²	0	29.9 Å²	29.9	0%	0	15%	0.152	C	C	.	.	H	α-helix	trans	-66.1	-28.6	179	-62.8	0	0	0	0	112.7	N53 D81 F300 S301	N53-S303 PolarHBondContact ND2-O 3.45Å; D81-S303 VanDerWaalsContact OD1-CB 3.3Å; D81-S303 WeakPolarHBondContact OD1-CB 2.86Å; D81-S303 PolarHBondContact OD1-OG 3.21Å; F300-S303 PolarHBondContact O-N 2.81Å; S301-S303 VanDerWaalsContact C-N 3.28Å; S301-S303 PolarHBondContact O-N 3.04Å
304	A	94.9	Very high	86.3	Confident	8 Å²	8	30.1 Å²	30.1	7%	0.066	15%	0.154	C	C	.	.	H	α-helix	trans	-80.2	-33.1	174.5	0	0	0	0	0	112.5	I45 L48 S301 N302 P307 F308	I45-A304 HydrophobicContact CG2-CB 4.15Å; L48-A304 HydrophobicContact CB-CB 4.39Å; S301-A304 WeakPolarHBondContact O-CA 3.33Å; S301-A304 PolarHBondContact O-N 3.15Å; N302-A304 VanDerWaalsContact C-N 3.26Å; N302-A304 PolarHBondContact O-N 3.08Å; A304-P307 WeakPolarHBondContact O-CD 3.11Å; A304-F308 WeakPolarHBondContact O-CD2 3.31Å; A304-F308 WeakPolarHBondContact O-CE2 3.48Å
305	I	93.9	Very high	84.8	Confident	56 Å²	56	29.7 Å²	29.7	29%	0.287	16%	0.155	S	C	.	.	H	α-helix	trans	-72.4	-35.9	-178	-69.1	162	0	0	0	112.1	A256 S301 N302 F308 L309	A256-I305 HydrophobicContact CB-CG2 3.91Å; S301-I305 VanDerWaalsContact O-CG1 3.29Å; S301-I305 WeakPolarHBondContact O-CG1 3.35Å; S301-I305 PolarHBondContact O-N 3.47Å; N302-I305 PolarHBondContact O-N 2.93Å; I305-F308 WeakPolarHBondContact O-CB 3.33Å; I305-F308 PolarHBondContact O-N 3.46Å; I305-L309 HydrophobicContact CG2-CD1 3.76Å; I305-L309 HydrophobicContact CG2-CD2 4.4Å; I305-L309 HydrophobicContact CG2-CG 3.83Å; I305-L309 PolarHBondContact O-N 3.48Å; I305-L309 VanDerWaalsContact O-N 3.1Å
306	N	89.4	Confident	83.1	Confident	0 Å²	0	32.3 Å²	32.3	0%	0	17%	0.166	C	C	.	.	H	α-helix	trans	-48.9	-53.3	-176	-78	-21.8	0	0	0	114	D81 N302 F308 L309 Y310	D81-N306 PolarHBondContact OD2-ND2 3.21Å; N302-N306 VanDerWaalsContact O-CG 3.32Å; N302-N306 PolarHBondContact O-N 3.2Å; N302-N306 VanDerWaalsContact O-N 3.16Å; N302-N306 PolarHBondContact O-ND2 3.17Å; N306-F308 VanDerWaalsContact C-N 3.32Å; N306-F308 PolarHBondContact O-N 2.95Å; N306-L309 PolarHBondContact O-N 3.45Å; N306-L309 VanDerWaalsContact O-N 3.12Å; N306-Y310 HydrophobicContact CB-CE2 3.91Å; N306-Y310 WeakPolarHBondContact O-CD2 3.42Å; N306-Y310 WeakPolarHBondContact O-CE2 3.36Å; N306-Y310 VanDerWaalsContact O-CG 3.3Å; N306-Y310 PolarHBondContact O-N 2.92Å
307	P	85.4	Confident	81.5	Confident	4 Å²	4	31.5 Å²	31.5	3%	0.026	16%	0.162	C	C	.	.	H	α-helix	trans	-54.7	-40.5	174.9	-28.8	34.9	0	0	0	114.8	G52 N53 V56 A304 L309 Y310 C311	G52-P307 VanDerWaalsContact C-CG 3.41Å; N53-P307 HydrophobicContact CB-CG 4.34Å; N53-P307 WeakPolarHBondContact OD1-CG 3.45Å; V56-P307 HydrophobicContact CG2-CB 4.04Å; V56-P307 HydrophobicContact CG2-CG 4.36Å; A304-P307 WeakPolarHBondContact O-CD 3.11Å; P307-L309 VanDerWaalsContact C-N 3.34Å; P307-Y310 PolarHBondContact O-N 2.85Å; P307-C311 WeakPolarHBondContact O-CB 3.31Å; P307-C311 PolarHBondContact O-N 2.78Å; P307-C311 PolarHBondContact O-SG 3.18Å
308	F	83.9	Confident	80.1	Confident	86 Å²	86	39.2 Å²	39.2	38%	0.377	19%	0.19	S	C	.	.	H	α-helix	trans	-64.1	-42.3	177.9	-64.2	-90.7	0	0	0	110.4	L48 A304 I305 N306 Y310 C311 F312	L48-F308 HydrophobicContact CB-CE2 4.29Å; L48-F308 HydrophobicContact CB-CZ 4.39Å; L48-F308 HydrophobicContact CD1-CZ 4.46Å; L48-F308 HydrophobicContact CD2-CZ 4.36Å; A304-F308 WeakPolarHBondContact O-CD2 3.31Å; A304-F308 WeakPolarHBondContact O-CE2 3.48Å; I305-F308 WeakPolarHBondContact O-CB 3.33Å; I305-F308 PolarHBondContact O-N 3.46Å; N306-F308 VanDerWaalsContact C-N 3.32Å; N306-F308 PolarHBondContact O-N 2.95Å; F308-Y310 VanDerWaalsContact C-N 3.3Å; F308-Y310 PolarHBondContact O-N 3.42Å; F308-C311 PolarHBondContact O-N 3.13Å; F308-F312 HydrophobicContact CB-CD2 4.07Å; F308-F312 HydrophobicContact CB-CE2 4.45Å; F308-F312 HydrophobicContact CD1-CD2 4.18Å; F308-F312 AromaticContact CD1-CE2 3.73Å; F308-F312 HydrophobicContact CD1-CE2 3.73Å; F308-F312 WeakPolarHBondContact O-CB 3.3Å; F308-F312 WeakPolarHBondContact O-CD2 3.4Å; F308-F312 PolarHBondContact O-N 3.1Å
309	L	85.2	Confident	78.8	Confident	28 Å²	28	39.2 Å²	39.2	15%	0.147	19%	0.188	C	C	.	.	H	α-helix	trans	-62.7	-38.8	176.9	-62	179.3	0	0	0	112	A252 V253 A256 I305 N306 P307 V313 G314	A252-L309 HydrophobicContact CB-CD1 4.45Å; A252-L309 HydrophobicContact CB-CD2 4.05Å; V253-L309 HydrophobicContact CB-CD1 4.32Å; V253-L309 HydrophobicContact CG2-CB 4.05Å; V253-L309 HydrophobicContact CG2-CD1 3.83Å; A256-L309 HydrophobicContact CB-CD1 3.67Å; I305-L309 HydrophobicContact CG2-CD1 3.76Å; I305-L309 HydrophobicContact CG2-CD2 4.4Å; I305-L309 HydrophobicContact CG2-CG 3.83Å; I305-L309 PolarHBondContact O-N 3.48Å; I305-L309 VanDerWaalsContact O-N 3.1Å; N306-L309 PolarHBondContact O-N 3.45Å; N306-L309 VanDerWaalsContact O-N 3.12Å; P307-L309 VanDerWaalsContact C-N 3.34Å; L309-V313 HydrophobicContact CD2-CG2 3.98Å; L309-V313 VanDerWaalsContact O-CB 3.28Å; L309-V313 WeakPolarHBondContact O-CB 3.19Å; L309-V313 PolarHBondContact O-N 3.43Å; L309-G314 PolarHBondContact O-N 2.92Å
310	Y	78.6	Confident	77.4	Confident	6 Å²	6	39.6 Å²	39.6	2%	0.024	19%	0.19	C	C	.	.	H	α-helix	trans	-66.4	-39.7	175.1	-52.8	-37.3	0	0	0	112.5	V56 I74 L77 M249 V253 N306 P307 F308 F317	V56-Y310 HydrophobicContact CG1-CD2 4.05Å; V56-Y310 HydrophobicContact CG1-CE2 4.37Å; V56-Y310 HydrophobicContact CG2-CD2 3.76Å; I74-Y310 HydrophobicContact CG1-CE1 4.32Å; I74-Y310 HydrophobicContact CG2-CD1 4.35Å; I74-Y310 HydrophobicContact CG2-CD2 3.97Å; I74-Y310 HydrophobicContact CG2-CE1 4.17Å; I74-Y310 HydrophobicContact CG2-CE2 3.78Å; I74-Y310 HydrophobicContact CG2-CG 4.28Å; L77-Y310 WeakPolarHBondContact CD2-OH 3.46Å; M249-Y310 HydrophobicContact CG-CD1 4.13Å; M249-Y310 HydrophobicContact SD-CD1 3.8Å; M249-Y310 HydrophobicContact SD-CE1 4.49Å; V253-Y310 HydrophobicContact CG2-CD1 4.44Å; V253-Y310 HydrophobicContact CG2-CE1 3.77Å; N306-Y310 HydrophobicContact CB-CE2 3.91Å; N306-Y310 WeakPolarHBondContact O-CD2 3.42Å; N306-Y310 WeakPolarHBondContact O-CE2 3.36Å; N306-Y310 VanDerWaalsContact O-CG 3.3Å; N306-Y310 PolarHBondContact O-N 2.92Å; P307-Y310 PolarHBondContact O-N 2.85Å; F308-Y310 VanDerWaalsContact C-N 3.3Å; F308-Y310 PolarHBondContact O-N 3.42Å; Y310-F317 WeakPolarHBondContact O-CB 3.36Å
311	C	69.6	Low	76.2	Confident	27 Å²	27	42 Å²	42	18%	0.182	20%	0.203	C	C	.	.	H	α-helix	trans	-72.7	-46.6	-179.1	-65.8	0	0	0	0	113	P307 F308 F317	P307-C311 WeakPolarHBondContact O-CB 3.31Å; P307-C311 PolarHBondContact O-N 2.78Å; P307-C311 PolarHBondContact O-SG 3.18Å; F308-C311 PolarHBondContact O-N 3.13Å; C311-F317 HydrophobicContact CB-CD1 4.21Å; C311-F317 WeakPolarHBondContact SG-CD1 3.48Å; C311-F317 WeakPolarHBondContact SG-CE1 3.24Å
312	F	65.5	Low	75	Confident	152 Å²	152	48.2 Å²	48.2	67%	0.667	22%	0.222	S	C	*	.	H	α-helix	trans	-98.6	-30.5	-166.5	-67.3	-77.2	0	0	0	113.9	F308	F308-F312 HydrophobicContact CB-CD2 4.07Å; F308-F312 HydrophobicContact CB-CE2 4.45Å; F308-F312 HydrophobicContact CD1-CD2 4.18Å; F308-F312 AromaticContact CD1-CE2 3.73Å; F308-F312 HydrophobicContact CD1-CE2 3.73Å; F308-F312 WeakPolarHBondContact O-CB 3.3Å; F308-F312 WeakPolarHBondContact O-CD2 3.4Å; F308-F312 PolarHBondContact O-N 3.1Å
313	V	59.9	Low	73.9	Confident	51 Å²	51	56.3 Å²	56.3	31%	0.309	25%	0.253	S	S	.	.	T	Hydrogen-bonded Turn	trans	-93.7	-31.4	-179.8	-172.4	0	0	0	0	111.4	K248 M249 A252 L309	K248-V313 HydrophobicContact CB-CG1 4.14Å; M249-V313 HydrophobicContact CB-CG1 4.4Å; A252-V313 HydrophobicContact CB-CG1 4.16Å; A252-V313 HydrophobicContact CB-CG2 4.2Å; L309-V313 HydrophobicContact CD2-CG2 3.98Å; L309-V313 VanDerWaalsContact O-CB 3.28Å; L309-V313 WeakPolarHBondContact O-CB 3.19Å; L309-V313 PolarHBondContact O-N 3.43Å
314	G	59.5	Low	72.7	Confident	5 Å²	5	56.9 Å²	56.9	5%	0.052	26%	0.256	C	S	.	.	S	Bend	trans	-76.5	-27.3	-174.3	0	0	0	0	0	115.9	L309 H316	L309-G314 PolarHBondContact O-N 2.92Å; G314-H316 PolarHBondContact O-N 3.35Å
315	N	58.6	Low	71.7	Confident	60 Å²	60	63.8 Å²	63.8	32%	0.321	28%	0.281	S	S	.	.	S	Bend	trans	50.2	-30.9	-164.2	-85.2	-0.5	0	0	0	116.3	F317 R318 E319	N315-F317 PolarHBondContact O-N 3.19Å; N315-R318 WeakPolarHBondContact O-CB 3.34Å; N315-R318 PolarHBondContact O-N 3.25Å; N315-E319 WeakPolarHBondContact O-CG 3.26Å; N315-E319 PolarHBondContact O-N 2.77Å
316	H	58.6	Low	70.9	Confident	69 Å²	69	66.8 Å²	66.8	32%	0.319	29%	0.294	S	S	.	.	H	α-helix	trans	-65	-37.4	-179.2	-169.1	58.9	0	0	0	112.7	G314 R318 E319 Q320	G314-H316 PolarHBondContact O-N 3.35Å; H316-R318 VanDerWaalsContact C-N 3.33Å; H316-E319 IonicContact ND1-OE2 2.82Å; H316-E319 PolarHBondContact O-N 2.93Å; H316-Q320 PolarHBondContact CD2-NE2 2.84Å; H316-Q320 VanDerWaalsContact CD2-NE2 3.31Å; H316-Q320 PolarHBondContact NE2-NE2 2.87Å; H316-Q320 WeakPolarHBondContact O-CB 3.05Å; H316-Q320 VanDerWaalsContact O-CG 3.28Å; H316-Q320 WeakPolarHBondContact O-CG 3.39Å; H316-Q320 PolarHBondContact O-N 3.22Å
317	F	60.2	Low	70.1	Confident	10 Å²	10	70.5 Å²	70.5	4%	0.044	31%	0.311	C	S	.	.	H	α-helix	trans	-65	-40	174.4	-170.1	-102.2	0	0	0	111.4	L55 V56 V59 L60 Y310 C311 N315 Q320 L321	L55-F317 HydrophobicContact CD2-CE1 4.31Å; L55-F317 HydrophobicContact CG-CE1 4.34Å; L55-F317 HydrophobicContact CG-CZ 4.1Å; V56-F317 HydrophobicContact CB-CE2 4.49Å; V56-F317 HydrophobicContact CG2-CE2 4.32Å; V56-F317 HydrophobicContact CG2-CZ 4.17Å; V59-F317 HydrophobicContact CB-CD2 4.26Å; V59-F317 HydrophobicContact CB-CE2 3.41Å; V59-F317 VanDerWaalsContact CB-CE2 3.41Å; V59-F317 HydrophobicContact CB-CZ 3.74Å; V59-F317 HydrophobicContact CG1-CD2 3.83Å; V59-F317 HydrophobicContact CG1-CE2 3.49Å; V59-F317 VanDerWaalsContact CG1-CE2 3.49Å; V59-F317 HydrophobicContact CG1-CZ 4.09Å; V59-F317 HydrophobicContact CG2-CE1 4.44Å; V59-F317 HydrophobicContact CG2-CE2 3.88Å; V59-F317 HydrophobicContact CG2-CZ 3.64Å; L60-F317 HydrophobicContact CD2-CD2 4.45Å; L60-F317 HydrophobicContact CG-CE2 4.46Å; Y310-F317 WeakPolarHBondContact O-CB 3.36Å; C311-F317 HydrophobicContact CB-CD1 4.21Å; C311-F317 WeakPolarHBondContact SG-CD1 3.48Å; C311-F317 WeakPolarHBondContact SG-CE1 3.24Å; N315-F317 PolarHBondContact O-N 3.19Å; F317-Q320 PolarHBondContact O-N 2.95Å; F317-L321 HydrophobicContact CD1-CD1 3.49Å; F317-L321 VanDerWaalsContact CD1-CD1 3.49Å; F317-L321 HydrophobicContact CD1-CG 4.06Å; F317-L321 HydrophobicContact CE1-CD1 3.28Å; F317-L321 HydrophobicContact CE1-CG 3.83Å; F317-L321 HydrophobicContact CZ-CD1 4.2Å; F317-L321 HydrophobicContact CZ-CG 4.34Å; F317-L321 VanDerWaalsContact O-CB 3.31Å; F317-L321 WeakPolarHBondContact O-CB 3.39Å; F317-L321 WeakPolarHBondContact O-CG 3.24Å; F317-L321 PolarHBondContact O-N 3.41Å
318	R	65.8	Low	69.3	Low	167 Å²	167	73.7 Å²	73.7	63%	0.63	33%	0.325	S	S	*	.	H	α-helix	trans	-65.5	-42.9	175.3	-160.3	179.2	86.2	-170.4	8.3	111.6	N315 H316 L321 W322	N315-R318 WeakPolarHBondContact O-CB 3.34Å; N315-R318 PolarHBondContact O-N 3.25Å; H316-R318 VanDerWaalsContact C-N 3.33Å; R318-L321 PolarHBondContact O-N 3.12Å; R318-W322 VanDerWaalsContact O-CB 3.24Å; R318-W322 WeakPolarHBondContact O-CB 3.3Å; R318-W322 PolarHBondContact O-N 3.43Å
319	E	68.2	Low	68.8	Low	66 Å²	66	71.1 Å²	71.1	31%	0.308	32%	0.319	S	S	.	.	H	α-helix	trans	-61.7	-41.9	174.4	-71.4	169.4	-170.6	0	0	111.6	R245 N315 H316 R323	R245-E319 IonicContact CZ-OE1 3.89Å; R245-E319 IonicContact NH1-OE1 2.82Å; R245-E319 PolarHBondContact NH1-OE1 3.27Å; R245-E319 IonicContact NH1-OE2 3.9Å; N315-E319 WeakPolarHBondContact O-CG 3.26Å; N315-E319 PolarHBondContact O-N 2.77Å; H316-E319 IonicContact ND1-OE2 2.82Å; H316-E319 PolarHBondContact O-N 2.93Å; E319-R323 WeakPolarHBondContact O-CB 3.35Å; E319-R323 VanDerWaalsContact O-CG 3.26Å; E319-R323 WeakPolarHBondContact O-CG 3.48Å; E319-R323 PolarHBondContact O-N 2.93Å
320	Q	67.5	Low	67.9	Low	7 Å²	7	73.5 Å²	73.5	3%	0.033	34%	0.336	C	S	.	.	H	α-helix	trans	-67.6	-45.8	175.5	-73.1	179.9	-1.5	0	0	112	V59 N65 H316 F317 W322 R323 L324	V59-Q320 HydrophobicContact CG1-CB 4.02Å; N65-Q320 PolarHBondContact ND2-OE1 3.42Å; N65-Q320 WeakPolarHBondContact OD1-CG 3.46Å; H316-Q320 PolarHBondContact CD2-NE2 2.84Å; H316-Q320 VanDerWaalsContact CD2-NE2 3.31Å; H316-Q320 PolarHBondContact NE2-NE2 2.87Å; H316-Q320 WeakPolarHBondContact O-CB 3.05Å; H316-Q320 VanDerWaalsContact O-CG 3.28Å; H316-Q320 WeakPolarHBondContact O-CG 3.39Å; H316-Q320 PolarHBondContact O-N 3.22Å; F317-Q320 PolarHBondContact O-N 2.95Å; Q320-W322 VanDerWaalsContact C-N 3.31Å; Q320-W322 PolarHBondContact O-N 3.36Å; Q320-R323 PolarHBondContact O-N 3.32Å; Q320-L324 WeakPolarHBondContact O-CB 3.47Å; Q320-L324 WeakPolarHBondContact O-CD1 3.48Å; Q320-L324 WeakPolarHBondContact O-CG 3.34Å; Q320-L324 PolarHBondContact O-N 2.95Å
321	L	68.1	Low	67.1	Low	54 Å²	54	80.2 Å²	80.2	28%	0.283	36%	0.362	S	S	.	.	H	α-helix	trans	-56.8	-45.2	174	-88.9	173.7	0	0	0	111.7	L55 V59 F317 R318 L324 Y325	L55-L321 HydrophobicContact CD1-CD2 4.11Å; V59-L321 HydrophobicContact CG2-CD2 3.34Å; V59-L321 HydrophobicContact CG2-CG 3.84Å; F317-L321 HydrophobicContact CD1-CD1 3.49Å; F317-L321 VanDerWaalsContact CD1-CD1 3.49Å; F317-L321 HydrophobicContact CD1-CG 4.06Å; F317-L321 HydrophobicContact CE1-CD1 3.28Å; F317-L321 HydrophobicContact CE1-CG 3.83Å; F317-L321 HydrophobicContact CZ-CD1 4.2Å; F317-L321 HydrophobicContact CZ-CG 4.34Å; F317-L321 VanDerWaalsContact O-CB 3.31Å; F317-L321 WeakPolarHBondContact O-CB 3.39Å; F317-L321 WeakPolarHBondContact O-CG 3.24Å; F317-L321 PolarHBondContact O-N 3.41Å; R318-L321 PolarHBondContact O-N 3.12Å; L321-L324 PolarHBondContact O-N 2.99Å; L321-Y325 WeakPolarHBondContact O-CB 3.39Å; L321-Y325 PolarHBondContact O-N 2.86Å
322	W	72.2	Confident	66.6	Low	157 Å²	157	84.3 Å²	84.3	60%	0.595	38%	0.381	S	S	*	.	H	α-helix	trans	-63	-47	178.5	-173.8	-95.6	0	0	0	111.4	R318 Q320 L324 Y325 E326	R318-W322 VanDerWaalsContact O-CB 3.24Å; R318-W322 WeakPolarHBondContact O-CB 3.3Å; R318-W322 PolarHBondContact O-N 3.43Å; Q320-W322 VanDerWaalsContact C-N 3.31Å; Q320-W322 PolarHBondContact O-N 3.36Å; W322-L324 VanDerWaalsContact C-N 3.28Å; W322-L324 PolarHBondContact O-N 3.41Å; W322-Y325 HydrophobicContact CZ3-CD1 4.43Å; W322-Y325 WeakPolarHBondContact O-CB 3.36Å; W322-Y325 PolarHBondContact O-N 2.9Å; W322-E326 WeakPolarHBondContact O-CB 3.21Å; W322-E326 PolarHBondContact O-N 2.82Å
323	R	71.9	Confident	66.6	Low	170 Å²	170	79 Å²	79	64%	0.642	36%	0.363	S	S	*	.	H	α-helix	trans	-59.5	-39	174.9	-73.2	175.3	-170.6	-166.4	2.9	112.6	E319 Q320 E326 E327	E319-R323 WeakPolarHBondContact O-CB 3.35Å; E319-R323 VanDerWaalsContact O-CG 3.26Å; E319-R323 WeakPolarHBondContact O-CG 3.48Å; E319-R323 PolarHBondContact O-N 2.93Å; Q320-R323 PolarHBondContact O-N 3.32Å; R323-E326 PolarHBondContact O-N 2.99Å; R323-E327 WeakPolarHBondContact O-CB 3.45Å; R323-E327 PolarHBondContact O-N 3.1Å
324	L	69.5	Low	66.7	Low	12 Å²	12	83.3 Å²	83.3	6%	0.063	38%	0.38	C	S	.	.	H	α-helix	trans	-69.3	-38.8	177.4	-70.8	163.3	0	0	0	112.2	V59 Q62 Q320 L321 W322 K328	V59-L324 HydrophobicContact CB-CD1 4.4Å; V59-L324 HydrophobicContact CG1-CD1 3.95Å; V59-L324 HydrophobicContact CG2-CD1 4.24Å; Q62-L324 HydrophobicContact CB-CD2 4.49Å; Q62-L324 VanDerWaalsContact OE1-CD2 3.3Å; Q320-L324 WeakPolarHBondContact O-CB 3.47Å; Q320-L324 WeakPolarHBondContact O-CD1 3.48Å; Q320-L324 WeakPolarHBondContact O-CG 3.34Å; Q320-L324 PolarHBondContact O-N 2.95Å; L321-L324 PolarHBondContact O-N 2.99Å; W322-L324 VanDerWaalsContact C-N 3.28Å; W322-L324 PolarHBondContact O-N 3.41Å; L324-K328 VanDerWaalsContact O-CB 3.26Å; L324-K328 WeakPolarHBondContact O-CB 3.35Å; L324-K328 WeakPolarHBondContact O-CG 3.36Å; L324-K328 PolarHBondContact O-N 3.15Å
325	Y	74.9	Confident	66.9	Low	153 Å²	153	89.8 Å²	89.8	60%	0.6	41%	0.406	S	S	*	.	H	α-helix	trans	-62.2	-46.9	171.8	177.8	-101	0	0	0	110.1	L321 W322 E327 K328 A329	L321-Y325 WeakPolarHBondContact O-CB 3.39Å; L321-Y325 PolarHBondContact O-N 2.86Å; W322-Y325 HydrophobicContact CZ3-CD1 4.43Å; W322-Y325 WeakPolarHBondContact O-CB 3.36Å; W322-Y325 PolarHBondContact O-N 2.9Å; Y325-E327 PolarHBondContact O-N 2.87Å; Y325-K328 PolarHBondContact O-N 3.27Å; Y325-A329 HydrophobicContact CE1-CB 4.38Å; Y325-A329 HydrophobicContact CE2-CB 4.4Å; Y325-A329 WeakPolarHBondContact O-CA 3.48Å; Y325-A329 WeakPolarHBondContact O-CB 3.29Å; Y325-A329 PolarHBondContact O-N 3.06Å
326	E	76.3	Confident	67.1	Low	119 Å²	119	95 Å²	95	56%	0.556	42%	0.422	S	S	*	.	H	α-helix	trans	-66.6	-34.7	179.9	-162	168.6	-160.8	0	0	112.9	W322 R323 P330	W322-E326 WeakPolarHBondContact O-CB 3.21Å; W322-E326 PolarHBondContact O-N 2.82Å; R323-E326 PolarHBondContact O-N 2.99Å; E326-P330 WeakPolarHBondContact O-CD 3.32Å; E326-P330 WeakPolarHBondContact O-CG 3.36Å
327	E	73.6	Confident	67.6	Low	78 Å²	78	95.7 Å²	95.7	36%	0.364	43%	0.427	S	S	.	.	H	α-helix	trans	-76.1	-34.5	175.6	-160.4	-165.5	149.6	0	0	112.5	R323 Y325 R331	R323-E327 WeakPolarHBondContact O-CB 3.45Å; R323-E327 PolarHBondContact O-N 3.1Å; Y325-E327 PolarHBondContact O-N 2.87Å; E327-R331 IonicContact OE1-CZ 3.29Å; E327-R331 VanDerWaalsContact OE1-CZ 3.29Å; E327-R331 IonicContact OE1-NH1 2.88Å; E327-R331 PolarHBondContact OE1-NH1 3.4Å; E327-R331 IonicContact OE1-NH2 2.89Å; E327-R331 PolarHBondContact OE1-NH2 3.41Å
328	K	68.3	Low	67.9	Low	71 Å²	71	98 Å²	98	31%	0.309	45%	0.445	S	S	.	.	H	α-helix	trans	-92.7	-27.3	-177.1	-70.1	-175.7	-177.7	175	0	114	L324 Y325 R331 L332	L324-K328 VanDerWaalsContact O-CB 3.26Å; L324-K328 WeakPolarHBondContact O-CB 3.35Å; L324-K328 WeakPolarHBondContact O-CG 3.36Å; L324-K328 PolarHBondContact O-N 3.15Å; Y325-K328 PolarHBondContact O-N 3.27Å; K328-R331 CarbonylContact O-C 3.42Å; K328-R331 PolarHBondContact O-N 2.88Å; K328-R331 VanDerWaalsContact O-N 3.17Å; K328-L332 HydrophobicContact CB-CD1 4.31Å; K328-L332 WeakPolarHBondContact O-CB 3.5Å; K328-L332 WeakPolarHBondContact O-CG 3.03Å; K328-L332 PolarHBondContact O-N 3.4Å
329	A	72.1	Confident	67.9	Low	31 Å²	31	94.3 Å²	94.3	26%	0.256	44%	0.437	S	S	.	.	H	α-helix	trans	-59.5	-43.5	-179.2	0	0	0	0	0	112.7	Y325 R331 L332 S333	Y325-A329 HydrophobicContact CE1-CB 4.38Å; Y325-A329 HydrophobicContact CE2-CB 4.4Å; Y325-A329 WeakPolarHBondContact O-CA 3.48Å; Y325-A329 WeakPolarHBondContact O-CB 3.29Å; Y325-A329 PolarHBondContact O-N 3.06Å; A329-R331 PolarHBondContact O-N 3.36Å; A329-L332 PolarHBondContact O-N 2.92Å; A329-S333 WeakPolarHBondContact O-CB 3.34Å; A329-S333 PolarHBondContact O-N 3.24Å
330	P	66.5	Low	67.9	Low	78 Å²	78	94.5 Å²	94.5	51%	0.506	45%	0.445	S	S	.	.	H	α-helix	trans	-63.9	-41.7	173.7	-18.5	30.2	0	0	0	111.7	E326 S333 Q334	E326-P330 WeakPolarHBondContact O-CD 3.32Å; E326-P330 WeakPolarHBondContact O-CG 3.36Å; P330-S333 PolarHBondContact O-N 2.88Å; P330-Q334 VanDerWaalsContact O-CB 3.28Å; P330-Q334 WeakPolarHBondContact O-CB 3.08Å; P330-Q334 PolarHBondContact O-N 3.38Å
331	R	61.4	Low	68	Low	147 Å²	147	98.3 Å²	98.3	56%	0.555	47%	0.469	S	S	*	.	H	α-helix	trans	-67.7	-36.7	179.6	-64.2	-176.8	-176.3	148.7	9.3	112.5	E327 K328 A329 K335	E327-R331 IonicContact OE1-CZ 3.29Å; E327-R331 VanDerWaalsContact OE1-CZ 3.29Å; E327-R331 IonicContact OE1-NH1 2.88Å; E327-R331 PolarHBondContact OE1-NH1 3.4Å; E327-R331 IonicContact OE1-NH2 2.89Å; E327-R331 PolarHBondContact OE1-NH2 3.41Å; K328-R331 CarbonylContact O-C 3.42Å; K328-R331 PolarHBondContact O-N 2.88Å; K328-R331 VanDerWaalsContact O-N 3.17Å; A329-R331 PolarHBondContact O-N 3.36Å; R331-K335 VanDerWaalsContact O-CB 3.25Å; R331-K335 WeakPolarHBondContact O-CB 3.33Å; R331-K335 PolarHBondContact O-N 2.93Å
332	L	60.5	Low	68	Low	113 Å²	113	104.5 Å²	104.5	59%	0.592	49%	0.489	S	S	*	.	H	α-helix	trans	-71.9	-38.8	175.5	-76.4	167.7	0	0	0	111.3	K328 A329 R336	K328-L332 HydrophobicContact CB-CD1 4.31Å; K328-L332 WeakPolarHBondContact O-CB 3.5Å; K328-L332 WeakPolarHBondContact O-CG 3.03Å; K328-L332 PolarHBondContact O-N 3.4Å; A329-L332 PolarHBondContact O-N 2.92Å; L332-R336 VanDerWaalsContact O-CB 3.28Å; L332-R336 WeakPolarHBondContact O-CB 3.26Å; L332-R336 PolarHBondContact O-N 3.4Å
333	S	65.3	Low	67.9	Low	40 Å²	40	102.6 Å²	102.6	28%	0.28	49%	0.49	S	S	.	.	H	α-helix	trans	-62.7	-50.2	171.6	-162.5	0	0	0	0	110.7	A329 P330 K335 R336 D337	A329-S333 WeakPolarHBondContact O-CB 3.34Å; A329-S333 PolarHBondContact O-N 3.24Å; P330-S333 PolarHBondContact O-N 2.88Å; S333-K335 VanDerWaalsContact C-N 3.31Å; S333-K335 PolarHBondContact O-N 3.08Å; S333-R336 CarbonylContact O-C 3.6Å; S333-R336 WeakPolarHBondContact O-CB 3.45Å; S333-R336 PolarHBondContact O-N 2.9Å; S333-R336 VanDerWaalsContact O-N 3.08Å; S333-D337 WeakPolarHBondContact O-CB 3.21Å; S333-D337 PolarHBondContact O-N 2.58Å; S333-D337 VanDerWaalsContact O-OD2 3.06Å; S333-D337 PolarHBondContact OG-OD2 3.44Å
334	Q	62.1	Low	67.9	Low	142 Å²	142	96.5 Å²	96.5	66%	0.664	47%	0.473	S	S	*	.	H	α-helix	trans	-63.6	-34.6	-179.4	-159.2	176.4	20.9	0	0	112.8	P330 S338	P330-Q334 VanDerWaalsContact O-CB 3.28Å; P330-Q334 WeakPolarHBondContact O-CB 3.08Å; P330-Q334 PolarHBondContact O-N 3.38Å; Q334-S338 VanDerWaalsContact O-CB 3.24Å; Q334-S338 WeakPolarHBondContact O-CB 3.28Å; Q334-S338 PolarHBondContact O-N 2.99Å
335	K	62.6	Low	67.9	Low	142 Å²	142	98.5 Å²	98.5	62%	0.617	49%	0.488	S	S	*	.	H	α-helix	trans	-70.6	-39.3	173.4	-164.4	-179.7	-174	-174.2	0	111.9	R331 S333 I339	R331-K335 VanDerWaalsContact O-CB 3.25Å; R331-K335 WeakPolarHBondContact O-CB 3.33Å; R331-K335 PolarHBondContact O-N 2.93Å; S333-K335 VanDerWaalsContact C-N 3.31Å; S333-K335 PolarHBondContact O-N 3.08Å; K335-I339 HydrophobicContact CG-CD1 4.2Å; K335-I339 WeakPolarHBondContact O-CB 3.34Å; K335-I339 WeakPolarHBondContact O-CD1 3.5Å; K335-I339 VanDerWaalsContact O-CG1 3.23Å; K335-I339 WeakPolarHBondContact O-CG1 3.47Å; K335-I339 PolarHBondContact O-N 3.23Å
336	R	64.1	Low	67.8	Low	170 Å²	170	98.2 Å²	98.2	64%	0.642	49%	0.49	S	S	*	.	H	α-helix	trans	-63.7	-43.5	173.4	178.9	175.8	61.5	178	-2.7	111.3	L332 S333 I339 S340	L332-R336 VanDerWaalsContact O-CB 3.28Å; L332-R336 WeakPolarHBondContact O-CB 3.26Å; L332-R336 PolarHBondContact O-N 3.4Å; S333-R336 CarbonylContact O-C 3.6Å; S333-R336 WeakPolarHBondContact O-CB 3.45Å; S333-R336 PolarHBondContact O-N 2.9Å; S333-R336 VanDerWaalsContact O-N 3.08Å; R336-I339 PolarHBondContact O-N 3.29Å; R336-S340 WeakPolarHBondContact O-CB 3.27Å; R336-S340 PolarHBondContact O-N 3.49Å
337	D	67.8	Low	67.6	Low	82 Å²	82	96.1 Å²	96.1	44%	0.439	49%	0.489	S	S	.	.	H	α-helix	trans	-65.8	-43.4	177.7	-60.6	-27.7	0	0	0	110.4	S333 I339 S340 T341	S333-D337 WeakPolarHBondContact O-CB 3.21Å; S333-D337 PolarHBondContact O-N 2.58Å; S333-D337 VanDerWaalsContact O-OD2 3.06Å; S333-D337 PolarHBondContact OG-OD2 3.44Å; D337-I339 PolarHBondContact O-N 3.1Å; D337-S340 WeakPolarHBondContact O-CB 3.32Å; D337-S340 PolarHBondContact O-N 3.24Å; D337-T341 PolarHBondContact O-N 3.33Å; D337-T341 PolarHBondContact O-OG1 2.73Å
338	S	67.1	Low	67.5	Low	60 Å²	60	99.8 Å²	99.8	42%	0.42	50%	0.5	S	S	.	.	H	α-helix	trans	-59.1	-42.5	173.9	-178.6	0	0	0	0	113.3	Q334 R342	Q334-S338 VanDerWaalsContact O-CB 3.24Å; Q334-S338 WeakPolarHBondContact O-CB 3.28Å; Q334-S338 PolarHBondContact O-N 2.99Å; S338-R342 WeakPolarHBondContact O-CG 3.35Å; S338-R342 PolarHBondContact O-N 2.9Å; S338-R342 VanDerWaalsContact O-N 3.09Å
339	I	66.2	Low	67.8	Low	88 Å²	88	103.3 Å²	103.3	45%	0.451	52%	0.515	S	S	.	.	H	α-helix	trans	-67.6	-43.1	176.7	-70.7	166.1	0	0	0	110.7	K335 R336 D337 R342 L343	K335-I339 HydrophobicContact CG-CD1 4.2Å; K335-I339 WeakPolarHBondContact O-CB 3.34Å; K335-I339 WeakPolarHBondContact O-CD1 3.5Å; K335-I339 VanDerWaalsContact O-CG1 3.23Å; K335-I339 WeakPolarHBondContact O-CG1 3.47Å; K335-I339 PolarHBondContact O-N 3.23Å; R336-I339 PolarHBondContact O-N 3.29Å; D337-I339 PolarHBondContact O-N 3.1Å; I339-R342 PolarHBondContact O-N 3.38Å; I339-L343 HydrophobicContact CG2-CD1 3.77Å; I339-L343 PolarHBondContact O-N 2.91Å
340	S	68.8	Low	67.6	Low	70 Å²	70	107.1 Å²	107.1	49%	0.49	53%	0.53	S	S	.	.	H	α-helix	trans	-59.4	-45.9	175.1	-175.9	0	0	0	0	111.7	R336 D337 R342 L343 S344	R336-S340 WeakPolarHBondContact O-CB 3.27Å; R336-S340 PolarHBondContact O-N 3.49Å; D337-S340 WeakPolarHBondContact O-CB 3.32Å; D337-S340 PolarHBondContact O-N 3.24Å; S340-R342 VanDerWaalsContact C-N 3.34Å; S340-R342 PolarHBondContact O-N 2.85Å; S340-L343 PolarHBondContact O-N 3.37Å; S340-S344 WeakPolarHBondContact O-CB 3.3Å; S340-S344 PolarHBondContact O-N 3.28Å
341	T	68.9	Low	67.8	Low	87 Å²	87	106 Å²	106	53%	0.534	52%	0.524	S	S	.	.	H	α-helix	trans	-62.3	-40.4	177.7	-48.7	0	0	0	0	111.6	D337 S344 S345	D337-T341 PolarHBondContact O-N 3.33Å; D337-T341 PolarHBondContact O-OG1 2.73Å; T341-S344 PolarHBondContact O-N 3.39Å; T341-S344 PolarHBondContact O-OG 3.05Å; T341-S345 PolarHBondContact O-N 2.05Å; T341-S345 PolarHBondContact O-OG 3Å
342	R	68.4	Low	68.3	Low	185 Å²	185	103.6 Å²	103.6	70%	0.698	52%	0.522	S	S	*	.	H	α-helix	trans	-66.4	-39.8	175.6	-75.5	179.6	173.6	-155	-2.1	113.2	S338 I339 S340 S344 S345 F346	S338-R342 WeakPolarHBondContact O-CG 3.35Å; S338-R342 PolarHBondContact O-N 2.9Å; S338-R342 VanDerWaalsContact O-N 3.09Å; I339-R342 PolarHBondContact O-N 3.38Å; S340-R342 VanDerWaalsContact C-N 3.34Å; S340-R342 PolarHBondContact O-N 2.85Å; R342-S344 VanDerWaalsContact C-N 3.35Å; R342-S345 PolarHBondContact O-N 3.35Å; R342-S345 PolarHBondContact O-OG 3.45Å; R342-F346 WeakPolarHBondContact O-CB 3.07Å; R342-F346 PolarHBondContact O-N 3.12Å
343	L	69.1	Low	68.4	Low	116 Å²	116	104.1 Å²	104.1	61%	0.607	53%	0.525	S	S	*	.	H	α-helix	trans	-65.4	-40.1	173.5	-87.6	148.6	0	0	0	111.2	I339 S340 S345 F346 S347	I339-L343 HydrophobicContact CG2-CD1 3.77Å; I339-L343 PolarHBondContact O-N 2.91Å; S340-L343 PolarHBondContact O-N 3.37Å; L343-S345 PolarHBondContact O-N 3.13Å; L343-F346 PolarHBondContact O-N 3Å; L343-S347 WeakPolarHBondContact O-CB 3.46Å; L343-S347 PolarHBondContact O-N 3.38Å
344	S	71.8	Confident	68.2	Low	42 Å²	42	110.8 Å²	110.8	29%	0.294	55%	0.549	S	S	.	.	H	α-helix	trans	-67.1	-34.2	177.1	84.1	0	0	0	0	113.2	S340 T341 R342 R348	S340-S344 WeakPolarHBondContact O-CB 3.3Å; S340-S344 PolarHBondContact O-N 3.28Å; T341-S344 PolarHBondContact O-N 3.39Å; T341-S344 PolarHBondContact O-OG 3.05Å; R342-S344 VanDerWaalsContact C-N 3.35Å; S344-R348 PolarHBondContact O-N 3.3Å; S344-R348 VanDerWaalsContact O-N 3.08Å; S344-R348 PolarHBondContact O-NE 2.95Å; S344-R348 PolarHBondContact OG-NH2 3.45Å
345	S	70.6	Confident	68	Low	55 Å²	55	110.6 Å²	110.6	39%	0.385	55%	0.553	S	S	.	*	H	α-helix	trans	-77.5	-34.5	177.2	66.1	0	0	0	0	111.7	T341 R342 L343 R348 K349	T341-S345 PolarHBondContact O-N 2.05Å; T341-S345 PolarHBondContact O-OG 3Å; R342-S345 PolarHBondContact O-N 3.35Å; R342-S345 PolarHBondContact O-OG 3.45Å; L343-S345 PolarHBondContact O-N 3.13Å; S345-R348 PolarHBondContact O-N 3.36Å; S345-K349 PolarHBondContact O-N 3.03Å
346	F	71.9	Confident	67.8	Low	146 Å²	146	109.2 Å²	109.2	64%	0.64	56%	0.556	S	S	*	*	H	α-helix	trans	-66.2	-42.6	171.9	-162.1	-97.5	0	0	0	111.5	R342 L343 R348 K349 L350	R342-F346 WeakPolarHBondContact O-CB 3.07Å; R342-F346 PolarHBondContact O-N 3.12Å; L343-F346 PolarHBondContact O-N 3Å; F346-R348 PolarHBondContact O-N 2.81Å; F346-K349 PolarHBondContact O-N 3.05Å; F346-L350 WeakPolarHBondContact O-CB 3.5Å; F346-L350 PolarHBondContact O-N 3.2Å
347	S	73.1	Confident	66.9	Low	76 Å²	76	103.9 Å²	103.9	53%	0.531	55%	0.554	S	S	.	*	H	α-helix	trans	-61.2	-41.8	174.3	-172.5	0	0	0	0	112.2	L343 L350 S351	L343-S347 WeakPolarHBondContact O-CB 3.46Å; L343-S347 PolarHBondContact O-N 3.38Å; S347-L350 PolarHBondContact O-N 2.87Å; S347-S351 PolarHBondContact O-N 3.47Å; S347-S351 PolarHBondContact O-OG 3.37Å
348	R	71.1	Confident	65.9	Low	155 Å²	155	105.9 Å²	105.9	59%	0.585	57%	0.572	S	S	*	*	H	α-helix	trans	-64	-44.4	176.3	-86.6	-178.7	-89.8	-174.6	-8.8	112.6	S344 S345 F346 L350 S351 D352	S344-R348 PolarHBondContact O-N 3.3Å; S344-R348 VanDerWaalsContact O-N 3.08Å; S344-R348 PolarHBondContact O-NE 2.95Å; S344-R348 PolarHBondContact OG-NH2 3.45Å; S345-R348 PolarHBondContact O-N 3.36Å; F346-R348 PolarHBondContact O-N 2.81Å; R348-L350 PolarHBondContact O-N 3.37Å; R348-S351 WeakPolarHBondContact CA-OG 3.43Å; R348-S351 PolarHBondContact O-N 3.07Å; R348-S351 PolarHBondContact O-OG 3.12Å; R348-D352 PolarHBondContact O-N 3.4Å
349	K	74.6	Confident	64.9	Low	145 Å²	145	111.2 Å²	111.2	63%	0.63	60%	0.595	S	S	*	*	H	α-helix	trans	-60.9	-35.1	173.6	-79.7	-174.8	173.9	-170.8	0	112.7	S345 F346 L353	S345-K349 PolarHBondContact O-N 3.03Å; F346-K349 PolarHBondContact O-N 3.05Å; K349-L353 WeakPolarHBondContact O-CB 3.33Å; K349-L353 WeakPolarHBondContact O-CD1 3.42Å; K349-L353 WeakPolarHBondContact O-CG 3.16Å; K349-L353 PolarHBondContact O-N 3.06Å
350	L	67.6	Low	63.7	Low	110 Å²	110	115.7 Å²	115.7	58%	0.576	61%	0.614	S	S	*	*	H	α-helix	trans	-71.8	-33.9	178.4	-155.8	76.6	0	0	0	112.1	F346 S347 R348 K354	F346-L350 WeakPolarHBondContact O-CB 3.5Å; F346-L350 PolarHBondContact O-N 3.2Å; S347-L350 PolarHBondContact O-N 2.87Å; R348-L350 PolarHBondContact O-N 3.37Å; L350-K354 PolarHBondContact O-N 3.37Å
351	S	71.1	Confident	62.5	Low	54 Å²	54	118.3 Å²	118.3	38%	0.378	63%	0.627	S	S	.	*	H	α-helix	trans	-70.1	-41.6	170.7	43.6	0	0	0	0	112.2	S347 R348 L353 K354 D355	S347-S351 PolarHBondContact O-N 3.47Å; S347-S351 PolarHBondContact O-OG 3.37Å; R348-S351 WeakPolarHBondContact CA-OG 3.43Å; R348-S351 PolarHBondContact O-N 3.07Å; R348-S351 PolarHBondContact O-OG 3.12Å; S351-L353 VanDerWaalsContact C-N 3.29Å; S351-L353 PolarHBondContact O-N 2.94Å; S351-K354 WeakPolarHBondContact O-CA 3.46Å; S351-K354 WeakPolarHBondContact O-CB 3.47Å; S351-K354 PolarHBondContact O-N 2.84Å; S351-D355 PolarHBondContact O-N 3.09Å; S351-D355 VanDerWaalsContact O-N 3.08Å
352	D	70.8	Confident	61.1	Low	97 Å²	97	121.6 Å²	121.6	52%	0.519	64%	0.64	S	S	.	*	H	α-helix	trans	-63.9	-35.1	177.8	-62.5	-21.5	0	0	0	111.9	R348 K354 D355 T356	R348-D352 PolarHBondContact O-N 3.4Å; D352-K354 VanDerWaalsContact C-N 3.28Å; D352-K354 PolarHBondContact O-N 3.34Å; D352-D355 PolarHBondContact O-N 3.36Å; D352-T356 PolarHBondContact O-N 3.31Å; D352-T356 PolarHBondContact O-OG1 3.07Å
353	L	63.5	Low	59.6	Low	125 Å²	125	119.8 Å²	119.8	65%	0.654	64%	0.644	S	S	*	*	H	α-helix	trans	-69.4	-24.2	172.7	-81	163.3	0	0	0	113.3	K349 S351 T356	K349-L353 WeakPolarHBondContact O-CB 3.33Å; K349-L353 WeakPolarHBondContact O-CD1 3.42Å; K349-L353 WeakPolarHBondContact O-CG 3.16Å; K349-L353 PolarHBondContact O-N 3.06Å; S351-L353 VanDerWaalsContact C-N 3.29Å; S351-L353 PolarHBondContact O-N 2.94Å; L353-T356 WeakPolarHBondContact CA-OG1 3.28Å
354	K	60.9	Low	58.4	Low	179 Å²	179	122.6 Å²	122.6	78%	0.778	65%	0.654	S	S	*	*	H	α-helix	trans	-80.5	-27.5	175.7	-165.9	174	179.4	-176.5	0	111.7	L350 S351 D352	L350-K354 PolarHBondContact O-N 3.37Å; S351-K354 WeakPolarHBondContact O-CA 3.46Å; S351-K354 WeakPolarHBondContact O-CB 3.47Å; S351-K354 PolarHBondContact O-N 2.84Å; D352-K354 VanDerWaalsContact C-N 3.28Å; D352-K354 PolarHBondContact O-N 3.34Å
355	D	58.5	Low	56.9	Low	139 Å²	139	127.6 Å²	127.6	74%	0.743	67%	0.673	S	S	*	*	H	α-helix	trans	-85.4	-8.9	176.5	-72.1	-21.8	0	0	0	113.5	S351 D352	S351-D355 PolarHBondContact O-N 3.09Å; S351-D355 VanDerWaalsContact O-N 3.08Å; D352-D355 PolarHBondContact O-N 3.36Å
356	T	57.4	Low	55.4	Low	112 Å²	112	130.8 Å²	130.8	69%	0.687	70%	0.695	S	S	*	*	S	Bend	trans	-104	35.7	-176.6	38.3	0	0	0	0	115.5	D352 L353	D352-T356 PolarHBondContact O-N 3.31Å; D352-T356 PolarHBondContact O-OG1 3.07Å; L353-T356 WeakPolarHBondContact CA-OG1 3.28Å
357	G	45.1	Very low	54.5	Low	58 Å²	58	133.5 Å²	133.5	60%	0.598	70%	0.701	S	S	*	*	S	Bend	trans	-154.1	144.1	165.4	0	0	0	0	0	115
358	P	47.8	Very low	53.1	Low	124 Å²	124	133.2 Å²	133.2	81%	0.805	71%	0.71	S	S	*	*			cis	-107.6	140.9	-48.7	31.7	-19.3	0	0	0	110.7
359	L	45	Very low	52.1	Low	172 Å²	172	135.9 Å²	135.9	90%	0.901	75%	0.748	S	S	*	*			trans	-113.4	77.8	161.1	-133.6	119.2	0	0	0	107.9
360	E	42.6	Very low	51	Low	183 Å²	183	135.5 Å²	135.5	86%	0.855	75%	0.754	S	S	*	*			trans	-100.6	113.8	159	-95.8	-172.9	160.9	0	0	109.1
361	T	42.7	Very low	50.1	Low	125 Å²	125	136.8 Å²	136.8	77%	0.767	76%	0.763	S	S	*	*			trans	-70.4	124.5	163.9	44.1	0	0	0	0	110.7
362	L	38.7	Very low	49	Very low	155 Å²	155	141.4 Å²	141.4	81%	0.812	78%	0.784	S	S	*	*			trans	-121.6	130.6	151.3	-89.1	143.8	0	0	0	104.1
363	D	37.4	Very low	47.7	Very low	147 Å²	147	144 Å²	144	79%	0.786	80%	0.8	S	S	*	*			cis	-164.1	147.9	20.6	-147.9	-16.6	0	0	0	108
364	Q	43.3	Very low	46.7	Very low	175 Å²	175	145.2 Å²	145.2	82%	0.818	81%	0.809	S	S	*	*			trans	-101.5	129.7	176.3	-123.2	-176.5	6.7	0	0	109.9
365	H	42.3	Very low	45.7	Very low	147 Å²	147	142.9 Å²	142.9	68%	0.681	81%	0.811	S	S	*	*			trans	74	111	150.6	-107.8	53.7	0	0	0	119.9	R367	H365-R367 PolarHBondContact NE2-NE 3.1Å
366	S	37.8	Very low	44.8	Very low	122 Å²	122	143.2 Å²	143.2	85%	0.853	82%	0.816	S	S	*	*			trans	-137.1	121.3	133.9	-177.3	0	0	0	0	109.2
367	R	53.7	Low	43.9	Very low	204 Å²	204	145.6 Å²	145.6	77%	0.77	83%	0.826	S	S	*	*			trans	-80.1	150.4	167	-71.5	-179.9	-171.9	-175	-1.2	108.7	H365	H365-R367 PolarHBondContact NE2-NE 3.1Å
368	G	44	Very low	43.8	Very low	70 Å²	70	152.9 Å²	152.9	72%	0.722	85%	0.845	S	S	*	*			trans	-59.6	-179.1	-179.3	0	0	0	0	0	116.1
369	P	49.8	Very low	43.4	Very low	211 Å²	211	155.5 Å²	155.5	100%	1.37	85%	0.848	S	S	*	*				-109	0	67.4	0.7	18.4	0	0	0	115.6

Retrieved 369 of 369 residues in 717.9 ms (Link to these results)

U.S. Privacy Notice - Disclaimer / Registrations / Copyright Statement - Linking Policy - Notice of Privacy Practices (HIPAA) - Notice of Non‑Discrimination
© Copyright 2026 St. Jude Children's Research Hospital, a not-for-profit, section 501(c)(3).