A0A060WBE6_ONCMY Loading...

Gem-associated protein 2

The SMN complex catalyzes the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome, and thereby plays an important role in the splicing of cellular pre-mRNAs.

AlphaFold DB , UniProt , Accession A0A060WBE6, Species ONCMY (Oncorhynchus mykiss, Rainbow trout), Gene LOC110497723, Length 266 aa.

Structure Viewer

Loading PAE data...

(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	38.1	Very low	67	Low	247 Å²	247	154.8 Å²	154.8	100%	1.217	79%	0.789	S	S	*	*				0	97.4	0	-67.1	167.8	87.7	0	0	106.2	S3	M1-S3 PolarHBondContact O-N 3.28Å
2	K	43.5	Very low	68.9	Low	201 Å²	201	154.5 Å²	154.5	87%	0.874	79%	0.789	S	S	*	*			trans	-71.6	124.8	174.4	-82.9	176.7	172.8	180	0	106.1	D4	K2-D4 PolarHBondContact O-N 2.69Å; K2-D4 VanDerWaalsContact O-N 3.11Å
3	S	48.4	Very low	70.4	Confident	106 Å²	106	151.2 Å²	151.2	74%	0.741	77%	0.773	S	S	*	*			trans	-63.9	107.6	170.9	48.2	0	0	0	0	107.7	M1 A5	M1-S3 PolarHBondContact O-N 3.28Å; S3-A5 PolarHBondContact O-N 3.16Å
4	D	47.5	Very low	71.2	Confident	163 Å²	163	148.1 Å²	148.1	87%	0.872	77%	0.768	S	S	*	*			trans	-68.4	57.7	163.1	-69	-30.6	0	0	0	109	K2 E6	K2-D4 PolarHBondContact O-N 2.69Å; K2-D4 VanDerWaalsContact O-N 3.11Å; D4-E6 PolarHBondContact O-N 3.27Å
5	A	61.1	Low	71.6	Confident	75 Å²	75	140.5 Å²	140.5	62%	0.62	73%	0.73	S	S	*	*			trans	-76.6	113.8	162.7	0	0	0	0	0	105.4	S3 E7	S3-A5 PolarHBondContact O-N 3.16Å; A5-E7 PolarHBondContact O-N 2.97Å
6	E	75.5	Confident	71.3	Confident	192 Å²	192	139.2 Å²	139.2	90%	0.897	72%	0.72	S	S	*	*			trans	-51.4	107.5	166.1	-71.7	179.5	158.4	0	0	107.8	D4 L8	D4-E6 PolarHBondContact O-N 3.27Å; E6-L8 PolarHBondContact O-N 3.09Å
7	E	80.9	Confident	70.6	Confident	117 Å²	117	138 Å²	138	55%	0.547	72%	0.72	S	S	.	*			trans	-66.7	120.2	-177.1	-170.7	176.2	-169.2	0	0	107.8	A5 M9 P10	A5-E7 PolarHBondContact O-N 2.97Å; E7-M9 PolarHBondContact O-N 3.41Å; E7-M9 VanDerWaalsContact O-N 3.17Å; E7-P10 HydrophobicContact CB-CB 4.22Å; E7-P10 VanDerWaalsContact O-CD 3.3Å; E7-P10 WeakPolarHBondContact O-CD 3.36Å; E7-P10 WeakPolarHBondContact OE2-CA 3.49Å
8	L	83.1	Confident	69.1	Low	175 Å²	175	136.6 Å²	136.6	92%	0.916	72%	0.722	S	S	*	*	S	Bend	trans	-59.4	-28.4	-176.1	-72.1	169.7	0	0	0	113	E6	E6-L8 PolarHBondContact O-N 3.09Å
9	M	85.3	Confident	68	Low	165 Å²	165	130.9 Å²	130.9	81%	0.813	70%	0.7	S	S	*	*	S	Bend	trans	-135.6	81.1	173.5	-67.7	-166.4	-63.3	0	0	108.7	E7	E7-M9 PolarHBondContact O-N 3.41Å; E7-M9 VanDerWaalsContact O-N 3.17Å
10	P	89.1	Confident	66.9	Low	71 Å²	71	132.7 Å²	132.7	46%	0.461	71%	0.708	S	S	.	*			trans	-69.6	142.4	-175.1	29.3	-31.1	0	0	0	110.6	E7 L12	E7-P10 HydrophobicContact CB-CB 4.22Å; E7-P10 VanDerWaalsContact O-CD 3.3Å; E7-P10 WeakPolarHBondContact O-CD 3.36Å; E7-P10 WeakPolarHBondContact OE2-CA 3.49Å; P10-L12 HydrophobicContact CG-CD2 4.33Å; P10-L12 PolarHBondContact O-N 2.88Å; P10-L12 VanDerWaalsContact O-N 3.09Å
11	R	85.1	Confident	65.8	Low	191 Å²	191	135.7 Å²	135.7	72%	0.721	72%	0.718	S	S	*	*			trans	-72.2	104.6	174.8	-63	-178.6	-177.1	-170.4	-1.5	109.8
12	L	88.8	Confident	66.2	Low	151 Å²	151	127.9 Å²	127.9	79%	0.791	68%	0.684	S	S	*	*			trans	-87.6	-21.7	-179.4	-62.4	179.3	0	0	0	113.8	P10	P10-L12 HydrophobicContact CG-CD2 4.33Å; P10-L12 PolarHBondContact O-N 2.88Å; P10-L12 VanDerWaalsContact O-N 3.09Å
13	L	88.6	Confident	66.4	Low	111 Å²	111	122 Å²	122	58%	0.581	68%	0.681	S	S	*	*	S	Bend	trans	-105.2	130.4	179.9	-64.2	175.8	0	0	0	109.8	V15 L39	L13-V15 PolarHBondContact O-N 3.13Å; L13-L39 HydrophobicContact CB-CD1 3.83Å; L13-L39 HydrophobicContact CD1-CD1 4.04Å; L13-L39 HydrophobicContact CD1-CD2 3.83Å
14	P	82.5	Confident	66.7	Low	108 Å²	108	124 Å²	124	70%	0.701	68%	0.678	S	S	*	*			trans	-69.7	120.2	175.3	29.1	-32.3	0	0	0	108.8
15	V	76.6	Confident	67.2	Low	34 Å²	34	123.8 Å²	123.8	21%	0.206	68%	0.677	C	S	.	*			trans	-114.7	116.6	166.8	-175.9	0	0	0	0	105.9	L13 T17 L39 R40	L13-V15 PolarHBondContact O-N 3.13Å; V15-T17 PolarHBondContact O-N 2.66Å; V15-T17 VanDerWaalsContact O-N 3.15Å; V15-L39 HydrophobicContact CG2-CB 3.72Å; V15-L39 HydrophobicContact CG2-CD1 3.7Å; V15-L39 HydrophobicContact CG2-CG 4.29Å; V15-R40 HydrophobicContact CG1-CG 4.09Å
16	E	67	Low	67.2	Low	120 Å²	120	122.7 Å²	122.7	56%	0.561	66%	0.663	S	S	*	*			trans	-63.1	116.1	176.6	-67.8	176.7	-158.4	0	0	108.4	C18 Q36	E16-C18 PolarHBondContact O-N 3.09Å; E16-Q36 PolarHBondContact OE1-NE2 3.46Å
17	T	58.6	Low	66.8	Low	119 Å²	119	117.6 Å²	117.6	73%	0.73	64%	0.642	S	S	*	*			trans	-74.2	4.5	174.2	53.8	0	0	0	0	112.4	V15 G19	V15-T17 PolarHBondContact O-N 2.66Å; V15-T17 VanDerWaalsContact O-N 3.15Å; T17-G19 PolarHBondContact O-N 3.43Å; T17-G19 VanDerWaalsContact O-N 3.09Å
18	C	44.4	Very low	66.2	Low	112 Å²	112	115.6 Å²	115.6	76%	0.757	63%	0.634	S	S	*	*	T	Hydrogen-bonded Turn	trans	-77.9	92.3	-178.7	-155.9	0	0	0	0	108.5	E16	E16-C18 PolarHBondContact O-N 3.09Å
19	G	47.7	Very low	65.8	Low	29 Å²	29	114.4 Å²	114.4	30%	0.299	63%	0.629	S	S	.	*	T	Hydrogen-bonded Turn	trans	162.8	0.7	177.4	0	0	0	0	0	117.5	T17 E21 T22	T17-G19 PolarHBondContact O-N 3.43Å; T17-G19 VanDerWaalsContact O-N 3.09Å; G19-E21 PolarHBondContact O-N 3.07Å; G19-E21 VanDerWaalsContact O-N 3.16Å; G19-T22 PolarHBondContact O-N 3.15Å; G19-T22 VanDerWaalsContact O-O 3.13Å; G19-T22 PolarHBondContact O-OG1 3.42Å
20	I	47.3	Very low	65.7	Low	166 Å²	166	111.7 Å²	111.7	85%	0.851	61%	0.614	S	S	*	*	T	Hydrogen-bonded Turn	trans	-63.6	-16.9	170.1	-56.7	179.2	0	0	0	110.9
21	E	43.9	Very low	65.5	Low	196 Å²	196	113.5 Å²	113.5	92%	0.916	63%	0.626	S	S	*	*	T	Hydrogen-bonded Turn	trans	-94.3	-16	177.7	-64.4	-173.5	172.6	0	0	114.9	G19	G19-E21 PolarHBondContact O-N 3.07Å; G19-E21 VanDerWaalsContact O-N 3.16Å
22	T	45.2	Very low	65.6	Low	84 Å²	84	106.9 Å²	106.9	52%	0.515	61%	0.608	S	S	.	*	S	Bend	trans	-101.3	100.2	172.4	46.2	0	0	0	0	107.3	G19 E24	G19-T22 PolarHBondContact O-N 3.15Å; G19-T22 VanDerWaalsContact O-O 3.13Å; G19-T22 PolarHBondContact O-OG1 3.42Å; T22-E24 PolarHBondContact O-N 3.11Å
23	G	48.6	Very low	65.4	Low	78 Å²	78	110 Å²	110	80%	0.804	61%	0.609	S	S	*	*			trans	-64.1	53.6	177.1	0	0	0	0	0	113.9	D25	G23-D25 PolarHBondContact O-N 3.22Å
24	E	54.9	Low	65.3	Low	147 Å²	147	107.5 Å²	107.5	69%	0.687	60%	0.596	S	S	*	*			trans	-78.4	97.4	165.8	-66.2	-172.5	166.1	0	0	106.8	T22 V26	T22-E24 PolarHBondContact O-N 3.11Å; E24-V26 PolarHBondContact O-N 3.13Å
25	D	57.3	Low	65.5	Low	158 Å²	158	107.2 Å²	107.2	85%	0.845	60%	0.595	S	S	*	*			trans	-55.5	100	169.2	-73.1	-38.5	0	0	0	108.7	G23 N27	G23-D25 PolarHBondContact O-N 3.22Å; D25-N27 PolarHBondContact O-N 3.44Å
26	V	61.2	Low	65.9	Low	53 Å²	53	109.1 Å²	109.1	32%	0.321	60%	0.601	S	S	.	*			trans	-63.1	107.5	176.7	178.3	0	0	0	0	107.7	E24 L28 L44	E24-V26 PolarHBondContact O-N 3.13Å; V26-L28 PolarHBondContact O-N 3.1Å; V26-L28 VanDerWaalsContact O-N 3.13Å; V26-L44 HydrophobicContact CB-CD1 3.81Å; V26-L44 HydrophobicContact CG1-CD1 4.26Å; V26-L44 HydrophobicContact CG2-CD1 4.15Å
27	N	67.6	Low	66.7	Low	84 Å²	84	106.6 Å²	106.6	45%	0.449	59%	0.589	S	S	.	*			trans	-73.4	105.5	-177.2	-170.4	-10.4	0	0	0	110.3	D25 N29 E30	D25-N27 PolarHBondContact O-N 3.44Å; N27-N29 PolarHBondContact O-N 3.15Å; N27-N29 VanDerWaalsContact O-N 3.11Å; N27-N29 WeakPolarHBondContact OD1-CB 3.39Å; N27-N29 PolarHBondContact OD1-N 3.45Å; N27-N29 VanDerWaalsContact OD1-N 3.15Å; N27-E30 PolarHBondContact O-N 3.18Å
28	L	68.5	Low	68	Low	75 Å²	75	107.2 Å²	107.2	39%	0.393	58%	0.579	S	S	.	*	T	Hydrogen-bonded Turn	trans	-63.3	-13.7	-179.9	-68.3	166.6	0	0	0	113.8	V26 Q41 L48	V26-L28 PolarHBondContact O-N 3.1Å; V26-L28 VanDerWaalsContact O-N 3.13Å; L28-Q41 HydrophobicContact CD2-CG 3.53Å; L28-Q41 PolarHBondContact O-NE2 3.26Å; L28-L48 HydrophobicContact CD1-CD1 4.1Å
29	N	74.3	Confident	70.1	Confident	151 Å²	151	103.6 Å²	103.6	81%	0.807	55%	0.552	S	S	*	*	T	Hydrogen-bonded Turn	trans	-93.6	-7.1	-174.9	-66.4	-44.1	0	0	0	114.4	N27	N27-N29 PolarHBondContact O-N 3.15Å; N27-N29 VanDerWaalsContact O-N 3.11Å; N27-N29 WeakPolarHBondContact OD1-CB 3.39Å; N27-N29 PolarHBondContact OD1-N 3.45Å; N27-N29 VanDerWaalsContact OD1-N 3.15Å
30	E	82.5	Confident	71.8	Confident	107 Å²	107	105.7 Å²	105.7	50%	0.5	55%	0.551	S	S	.	*	S	Bend	trans	-103.5	144.8	176.3	-69.1	-173.2	-156.2	0	0	111.2	N27	N27-E30 PolarHBondContact O-N 3.18Å
31	P	85.6	Confident	73.7	Confident	110 Å²	110	99.3 Å²	99.3	71%	0.714	52%	0.518	S	S	*	.	P	Polyproline II helix	trans	-64.6	132.5	173	-17.1	29.8	0	0	0	110.7
32	P	86.3	Confident	75.8	Confident	51 Å²	51	92.4 Å²	92.4	33%	0.331	49%	0.489	S	S	.	.	P	Polyproline II helix	trans	-67.2	140	179.5	22.6	-27	0	0	0	110.6	E37 Y38	P32-E37 HydrophobicContact CB-CB 4.05Å; P32-Y38 HydrophobicContact CG-CD2 3.74Å; P32-Y38 HydrophobicContact CG-CG 4.3Å
33	R	85.4	Confident	77.8	Confident	216 Å²	216	92.8 Å²	92.8	82%	0.815	49%	0.485	S	S	*	.	S	Bend	trans	-96.7	-14.6	-175.9	-63	-177	-174.8	-174.5	5.1	112.5	E37	R33-E37 PolarHBondContact N-OE2 3.47Å
34	N	86.3	Confident	79.6	Confident	60 Å²	60	92.7 Å²	92.7	32%	0.321	47%	0.465	S	S	.	.	S	Bend	trans	-138.1	161.9	175.6	66.8	49.8	0	0	0	112.9	Q36 E37 Y38	N34-Q36 VanDerWaalsContact C-N 3.32Å; N34-Q36 PolarHBondContact O-N 3.04Å; N34-Q36 PolarHBondContact OD1-N 2.78Å; N34-E37 VanDerWaalsContact CG-CD 3.44Å; N34-E37 PolarHBondContact N-OE2 2.97Å; N34-E37 PolarHBondContact ND2-OE1 3.22Å; N34-E37 PolarHBondContact O-N 3.39Å; N34-E37 WeakPolarHBondContact OD1-CB 3.46Å; N34-E37 WeakPolarHBondContact OD1-CG 3.31Å; N34-E37 PolarHBondContact OD1-N 3.25Å; N34-Y38 PolarHBondContact O-N 3.5Å; N34-Y38 VanDerWaalsContact O-N 3.16Å
35	P	85.8	Confident	81.3	Confident	102 Å²	102	91.2 Å²	91.2	66%	0.662	46%	0.458	S	S	*	.	H	α-helix	trans	-64.7	-29.6	-178.8	-24	35.1	0	0	0	114.7	L39	P35-L39 WeakPolarHBondContact O-CG 3.38Å; P35-L39 PolarHBondContact O-N 3.37Å
36	Q	85.3	Confident	82.8	Confident	73 Å²	73	86.6 Å²	86.6	34%	0.341	44%	0.442	S	S	.	.	H	α-helix	trans	-74.3	-38	-179.4	-70.5	-176.8	-22.5	0	0	112.3	E16 N34 L39 R40	E16-Q36 PolarHBondContact OE1-NE2 3.46Å; N34-Q36 VanDerWaalsContact C-N 3.32Å; N34-Q36 PolarHBondContact O-N 3.04Å; N34-Q36 PolarHBondContact OD1-N 2.78Å; Q36-L39 PolarHBondContact O-N 2.96Å; Q36-R40 WeakPolarHBondContact O-CG 3.41Å; Q36-R40 PolarHBondContact O-N 3.25Å
37	E	83.4	Confident	84.1	Confident	68 Å²	68	88.2 Å²	88.2	32%	0.318	46%	0.456	S	S	.	.	H	α-helix	trans	-62.4	-44.4	170.3	-78.4	164.9	-164.2	0	0	110.5	P32 R33 N34 L39 R40 Q41	P32-E37 HydrophobicContact CB-CB 4.05Å; R33-E37 PolarHBondContact N-OE2 3.47Å; N34-E37 VanDerWaalsContact CG-CD 3.44Å; N34-E37 PolarHBondContact N-OE2 2.97Å; N34-E37 PolarHBondContact ND2-OE1 3.22Å; N34-E37 PolarHBondContact O-N 3.39Å; N34-E37 WeakPolarHBondContact OD1-CB 3.46Å; N34-E37 WeakPolarHBondContact OD1-CG 3.31Å; N34-E37 PolarHBondContact OD1-N 3.25Å; E37-L39 PolarHBondContact O-N 2.84Å; E37-R40 PolarHBondContact O-N 3.05Å; E37-Q41 WeakPolarHBondContact O-CB 3.19Å; E37-Q41 PolarHBondContact O-N 3.47Å
38	Y	86.1	Confident	85.1	Confident	132 Å²	132	90.4 Å²	90.4	52%	0.518	47%	0.467	S	S	.	.	H	α-helix	trans	-58	-49	175.6	176.5	-101.6	0	0	0	111.6	P32 N34 R40 Q41 V42	P32-Y38 HydrophobicContact CG-CD2 3.74Å; P32-Y38 HydrophobicContact CG-CG 4.3Å; N34-Y38 PolarHBondContact O-N 3.5Å; N34-Y38 VanDerWaalsContact O-N 3.16Å; Y38-R40 VanDerWaalsContact C-N 3.32Å; Y38-R40 PolarHBondContact O-N 3.37Å; Y38-Q41 PolarHBondContact O-N 2.84Å; Y38-V42 HydrophobicContact CD1-CG2 4.33Å; Y38-V42 HydrophobicContact CD2-CG2 4.38Å; Y38-V42 HydrophobicContact CE1-CG2 3.91Å; Y38-V42 HydrophobicContact CE2-CG2 3.96Å; Y38-V42 VanDerWaalsContact O-CG2 3.32Å; Y38-V42 WeakPolarHBondContact O-CG2 3.48Å; Y38-V42 PolarHBondContact O-N 2.83Å
39	L	88.1	Confident	86.2	Confident	36 Å²	36	90.3 Å²	90.3	19%	0.188	47%	0.472	C	S	.	.	H	α-helix	trans	-64.4	-34.8	178.9	-69.3	176.1	0	0	0	112.8	L13 V15 P35 Q36 E37 Q43	L13-L39 HydrophobicContact CB-CD1 3.83Å; L13-L39 HydrophobicContact CD1-CD1 4.04Å; L13-L39 HydrophobicContact CD1-CD2 3.83Å; V15-L39 HydrophobicContact CG2-CB 3.72Å; V15-L39 HydrophobicContact CG2-CD1 3.7Å; V15-L39 HydrophobicContact CG2-CG 4.29Å; P35-L39 WeakPolarHBondContact O-CG 3.38Å; P35-L39 PolarHBondContact O-N 3.37Å; Q36-L39 PolarHBondContact O-N 2.96Å; E37-L39 PolarHBondContact O-N 2.84Å; L39-Q43 WeakPolarHBondContact O-CB 3.45Å; L39-Q43 VanDerWaalsContact O-CG 3.31Å; L39-Q43 WeakPolarHBondContact O-CG 3.42Å; L39-Q43 PolarHBondContact O-N 2.86Å
40	R	84.3	Confident	87.1	Confident	73 Å²	73	87.6 Å²	87.6	28%	0.275	46%	0.462	S	S	.	.	H	α-helix	trans	-66.7	-43.8	172.9	-77.4	-173.6	-81.5	177	-5	112	V15 Q36 E37 Y38 V42 Q43 L44	V15-R40 HydrophobicContact CG1-CG 4.09Å; Q36-R40 WeakPolarHBondContact O-CG 3.41Å; Q36-R40 PolarHBondContact O-N 3.25Å; E37-R40 PolarHBondContact O-N 3.05Å; Y38-R40 VanDerWaalsContact C-N 3.32Å; Y38-R40 PolarHBondContact O-N 3.37Å; R40-V42 VanDerWaalsContact C-N 3.32Å; R40-V42 PolarHBondContact O-N 3.37Å; R40-Q43 PolarHBondContact O-N 3.41Å; R40-L44 WeakPolarHBondContact O-CG 3.4Å; R40-L44 PolarHBondContact O-N 3.28Å
41	Q	86.4	Confident	87.5	Confident	32 Å²	32	90.4 Å²	90.4	15%	0.15	48%	0.481	C	S	.	.	H	α-helix	trans	-60.4	-43.1	176.3	-167.1	176.4	0.9	0	0	111.2	L28 E37 Y38 L44 E45	L28-Q41 HydrophobicContact CD2-CG 3.53Å; L28-Q41 PolarHBondContact O-NE2 3.26Å; E37-Q41 WeakPolarHBondContact O-CB 3.19Å; E37-Q41 PolarHBondContact O-N 3.47Å; Y38-Q41 PolarHBondContact O-N 2.84Å; Q41-L44 PolarHBondContact O-N 3.49Å; Q41-E45 WeakPolarHBondContact O-CB 3.17Å; Q41-E45 PolarHBondContact O-N 2.96Å
42	V	88.6	Confident	87.9	Confident	51 Å²	51	90.6 Å²	90.6	31%	0.309	48%	0.479	S	S	.	.	H	α-helix	trans	-65.8	-40.6	175.7	171.2	0	0	0	0	111.9	Y38 R40 L44 E45 A46	Y38-V42 HydrophobicContact CD1-CG2 4.33Å; Y38-V42 HydrophobicContact CD2-CG2 4.38Å; Y38-V42 HydrophobicContact CE1-CG2 3.91Å; Y38-V42 HydrophobicContact CE2-CG2 3.96Å; Y38-V42 VanDerWaalsContact O-CG2 3.32Å; Y38-V42 WeakPolarHBondContact O-CG2 3.48Å; Y38-V42 PolarHBondContact O-N 2.83Å; R40-V42 VanDerWaalsContact C-N 3.32Å; R40-V42 PolarHBondContact O-N 3.37Å; V42-L44 VanDerWaalsContact C-N 3.34Å; V42-E45 PolarHBondContact O-N 3.05Å; V42-A46 WeakPolarHBondContact O-CB 3.33Å; V42-A46 PolarHBondContact O-N 2.73Å
43	Q	87.6	Confident	88.2	Confident	92 Å²	92	93.6 Å²	93.6	43%	0.43	50%	0.497	S	S	.	.	H	α-helix	trans	-63	-41	175.3	-78.6	177.5	-7.5	0	0	112	L39 R40 S47	L39-Q43 WeakPolarHBondContact O-CB 3.45Å; L39-Q43 VanDerWaalsContact O-CG 3.31Å; L39-Q43 WeakPolarHBondContact O-CG 3.42Å; L39-Q43 PolarHBondContact O-N 2.86Å; R40-Q43 PolarHBondContact O-N 3.41Å; Q43-S47 WeakPolarHBondContact O-CB 3.32Å; Q43-S47 PolarHBondContact O-N 3.5Å
44	L	87.2	Confident	88.6	Confident	76 Å²	76	89.7 Å²	89.7	40%	0.398	50%	0.497	S	S	.	.	H	α-helix	trans	-67.8	-48.6	175.9	-70.9	170.1	0	0	0	111.4	V26 R40 Q41 V42 A46 S47 L48	V26-L44 HydrophobicContact CB-CD1 3.81Å; V26-L44 HydrophobicContact CG1-CD1 4.26Å; V26-L44 HydrophobicContact CG2-CD1 4.15Å; R40-L44 WeakPolarHBondContact O-CG 3.4Å; R40-L44 PolarHBondContact O-N 3.28Å; Q41-L44 PolarHBondContact O-N 3.49Å; V42-L44 VanDerWaalsContact C-N 3.34Å; L44-A46 PolarHBondContact O-N 3.06Å; L44-S47 WeakPolarHBondContact O-CB 3.25Å; L44-S47 PolarHBondContact O-N 3.23Å; L44-S47 VanDerWaalsContact O-N 3.09Å; L44-S47 PolarHBondContact O-OG 3.46Å; L44-L48 WeakPolarHBondContact O-CG 3.19Å; L44-L48 PolarHBondContact O-N 3.38Å; L44-L48 VanDerWaalsContact O-N 3.07Å
45	E	89.1	Confident	88.9	Confident	116 Å²	116	90.8 Å²	90.8	54%	0.542	51%	0.514	S	S	.	.	H	α-helix	trans	-56.9	-48.1	176.2	-177.3	-179.5	-160.2	0	0	111.4	Q41 V42 S47 L48 C49	Q41-E45 WeakPolarHBondContact O-CB 3.17Å; Q41-E45 PolarHBondContact O-N 2.96Å; V42-E45 PolarHBondContact O-N 3.05Å; E45-S47 VanDerWaalsContact C-N 3.3Å; E45-S47 PolarHBondContact O-N 3.16Å; E45-L48 WeakPolarHBondContact O-CB 3.38Å; E45-L48 PolarHBondContact O-N 3.11Å; E45-L48 VanDerWaalsContact O-N 3.1Å; E45-C49 PolarHBondContact O-N 3.43Å; E45-C49 VanDerWaalsContact O-N 3.13Å; E45-C49 PolarHBondContact O-SG 2.92Å; E45-C49 VanDerWaalsContact O-SG 3.41Å
46	A	88.5	Confident	89.1	Confident	61 Å²	61	96 Å²	96	50%	0.504	53%	0.526	S	S	.	.	H	α-helix	trans	-62.5	-34.5	175.9	0	0	0	0	0	112.7	V42 L44 L48 C49	V42-A46 WeakPolarHBondContact O-CB 3.33Å; V42-A46 PolarHBondContact O-N 2.73Å; L44-A46 PolarHBondContact O-N 3.06Å; A46-L48 VanDerWaalsContact C-N 3.27Å; A46-L48 PolarHBondContact O-N 2.81Å; A46-C49 WeakPolarHBondContact O-CB 3.37Å; A46-C49 PolarHBondContact O-N 2.9Å
47	S	88.3	Confident	89.2	Confident	86 Å²	86	98.4 Å²	98.4	60%	0.601	54%	0.54	S	S	*	.	H	α-helix	trans	-69.2	-24.1	175.2	77.7	0	0	0	0	113.7	Q43 L44 E45	Q43-S47 WeakPolarHBondContact O-CB 3.32Å; Q43-S47 PolarHBondContact O-N 3.5Å; L44-S47 WeakPolarHBondContact O-CB 3.25Å; L44-S47 PolarHBondContact O-N 3.23Å; L44-S47 VanDerWaalsContact O-N 3.09Å; L44-S47 PolarHBondContact O-OG 3.46Å; E45-S47 VanDerWaalsContact C-N 3.3Å; E45-S47 PolarHBondContact O-N 3.16Å
48	L	89.8	Confident	89.4	Confident	130 Å²	130	98.7 Å²	98.7	68%	0.681	54%	0.544	S	S	*	.	H	α-helix	trans	-80.9	-25.1	173.2	-64.3	170.3	0	0	0	111.8	L28 L44 E45 A46	L28-L48 HydrophobicContact CD1-CD1 4.1Å; L44-L48 WeakPolarHBondContact O-CG 3.19Å; L44-L48 PolarHBondContact O-N 3.38Å; L44-L48 VanDerWaalsContact O-N 3.07Å; E45-L48 WeakPolarHBondContact O-CB 3.38Å; E45-L48 PolarHBondContact O-N 3.11Å; E45-L48 VanDerWaalsContact O-N 3.1Å; A46-L48 VanDerWaalsContact C-N 3.27Å; A46-L48 PolarHBondContact O-N 2.81Å
49	C	91.3	Very high	89.2	Confident	74 Å²	74	96.2 Å²	96.2	50%	0.5	54%	0.544	S	S	.	.	S	Bend	trans	-71.5	142.7	173.8	-66.5	0	0	0	0	111.1	E45 A46 D51	E45-C49 PolarHBondContact O-N 3.43Å; E45-C49 VanDerWaalsContact O-N 3.13Å; E45-C49 PolarHBondContact O-SG 2.92Å; E45-C49 VanDerWaalsContact O-SG 3.41Å; A46-C49 WeakPolarHBondContact O-CB 3.37Å; A46-C49 PolarHBondContact O-N 2.9Å; C49-D51 PolarHBondContact O-N 3.09Å
50	P	92.6	Very high	88.9	Confident	93 Å²	93	102 Å²	102	60%	0.604	57%	0.567	S	S	*	*			trans	-64.5	128.7	170.8	26.8	-33.8	0	0	0	110.5	V52 V53	P50-V52 VanDerWaalsContact C-N 3.25Å; P50-V52 PolarHBondContact O-N 3.27Å; P50-V53 HydrophobicContact CB-CG1 4.09Å; P50-V53 HydrophobicContact CG-CG1 3.45Å; P50-V53 VanDerWaalsContact CG-CG1 3.45Å
51	D	91.1	Very high	88.7	Confident	167 Å²	167	105.8 Å²	105.8	89%	0.893	59%	0.586	S	S	*	*	S	Bend	trans	-59.9	-34.7	-178.1	-170.4	44.4	0	0	0	112.9	C49	C49-D51 PolarHBondContact O-N 3.09Å
52	V	93.7	Very high	88.3	Confident	113 Å²	113	109.9 Å²	109.9	69%	0.685	61%	0.608	S	S	*	*			trans	-129.2	127.3	175.8	-177.7	0	0	0	0	110.1	P50 V54	P50-V52 VanDerWaalsContact C-N 3.25Å; P50-V52 PolarHBondContact O-N 3.27Å; V52-V54 HydrophobicContact CG1-CG2 4.45Å
53	V	94.1	Very high	87.9	Confident	115 Å²	115	117.2 Å²	117.2	70%	0.697	63%	0.63	S	S	*	*			trans	-118.9	137.8	173.4	-64.7	0	0	0	0	110.5	P50	P50-V53 HydrophobicContact CB-CG1 4.09Å; P50-V53 HydrophobicContact CG-CG1 3.45Å; P50-V53 VanDerWaalsContact CG-CG1 3.45Å
54	V	93.8	Very high	87.5	Confident	134 Å²	134	121.6 Å²	121.6	81%	0.812	65%	0.648	S	S	*	*			trans	-121.1	114.1	179.1	-177.2	0	0	0	0	109.9	V52	V52-V54 HydrophobicContact CG1-CG2 4.45Å
55	A	92.4	Very high	87.3	Confident	82 Å²	82	126.8 Å²	126.8	68%	0.678	67%	0.667	S	S	*	*			trans	-84.4	131.2	175.2	0	0	0	0	0	111.2	I57	A55-I57 PolarHBondContact O-N 3.17Å
56	K	89.2	Confident	87	Confident	211 Å²	211	128.9 Å²	128.9	92%	0.917	68%	0.677	S	S	*	*			trans	-80.5	117.4	175.5	-65.7	-177.9	-177.5	177	0	110
57	I	87.4	Confident	87	Confident	125 Å²	125	131.4 Å²	131.4	64%	0.641	69%	0.686	S	S	*	*			trans	-116.5	147.3	178.3	-56.8	172	0	0	0	108.9	A55 P59	A55-I57 PolarHBondContact O-N 3.17Å; I57-P59 VanDerWaalsContact O-CD 3.25Å; I57-P59 WeakPolarHBondContact O-CD 3.3Å
58	D	87.3	Confident	87	Confident	74 Å²	74	133.5 Å²	133.5	40%	0.396	70%	0.695	S	S	.	*			trans	-69	112.5	174.9	179.1	5.6	0	0	0	111.3	K60 K61	D58-K60 PolarHBondContact O-N 3.03Å; D58-K60 WeakPolarHBondContact OD1-CB 3.45Å; D58-K60 PolarHBondContact OD1-N 3.22Å; D58-K61 PolarHBondContact O-N 3.25Å
59	P	82.3	Confident	87	Confident	80 Å²	80	134.1 Å²	134.1	52%	0.519	70%	0.699	S	S	.	*	H	α-helix	trans	-68.5	-19.2	-175.7	28.3	-35.4	0	0	0	113.3	I57 K61 L62 R63	I57-P59 VanDerWaalsContact O-CD 3.25Å; I57-P59 WeakPolarHBondContact O-CD 3.3Å; P59-K61 PolarHBondContact O-N 3.26Å; P59-L62 PolarHBondContact O-N 3.32Å; P59-R63 PolarHBondContact O-N 2.95Å
60	K	82.7	Confident	86.9	Confident	157 Å²	157	137 Å²	137	68%	0.683	71%	0.714	S	S	*	*	H	α-helix	trans	-66.7	-27	-179.1	-64.6	179.3	-178.7	177.4	0	112.4	D58	D58-K60 PolarHBondContact O-N 3.03Å; D58-K60 WeakPolarHBondContact OD1-CB 3.45Å; D58-K60 PolarHBondContact OD1-N 3.22Å
61	K	78.6	Confident	86.6	Confident	152 Å²	152	137.3 Å²	137.3	66%	0.661	72%	0.719	S	S	*	*	H	α-helix	trans	-74.1	-29.6	178.2	-64.7	-177.5	-178.4	179	0	112.5	D58 P59	D58-K61 PolarHBondContact O-N 3.25Å; P59-K61 PolarHBondContact O-N 3.26Å
62	L	79.1	Confident	86.3	Confident	119 Å²	119	135.1 Å²	135.1	62%	0.623	71%	0.707	S	S	*	*	H	α-helix	trans	-85	-39.8	-176.9	-62.5	173.6	0	0	0	112.3	P59 K64 K65	P59-L62 PolarHBondContact O-N 3.32Å; L62-K64 PolarHBondContact O-N 3.37Å; L62-K65 PolarHBondContact O-N 3.36Å
63	R	78.8	Confident	85.8	Confident	204 Å²	204	136.8 Å²	136.8	77%	0.77	71%	0.709	S	S	*	*	H	α-helix	trans	-61.6	-27.5	-179.5	-75.9	-173	168.9	-178.8	-2.6	114.4	P59 K65	P59-R63 PolarHBondContact O-N 2.95Å; R63-K65 VanDerWaalsContact C-N 3.26Å; R63-K65 PolarHBondContact O-N 3.08Å
64	K	81.3	Confident	85.4	Confident	184 Å²	184	133 Å²	133	80%	0.8	69%	0.692	S	S	*	*	T	Hydrogen-bonded Turn	trans	-72.3	-13.5	-178.6	-71.7	-175.3	178.6	-173.4	0	114.4	L62	L62-K64 PolarHBondContact O-N 3.37Å
65	K	81.2	Confident	85.3	Confident	185 Å²	185	127.9 Å²	127.9	80%	0.804	66%	0.662	S	S	*	*	T	Hydrogen-bonded Turn	trans	-124.1	18.1	-174.4	-62.7	-172.4	177.6	-174.1	0	113.2	L62 R63 T67	L62-K65 PolarHBondContact O-N 3.36Å; R63-K65 VanDerWaalsContact C-N 3.26Å; R63-K65 PolarHBondContact O-N 3.08Å; K65-T67 PolarHBondContact O-N 3.36Å
66	Q	83.6	Confident	85.1	Confident	160 Å²	160	128.3 Å²	128.3	75%	0.748	65%	0.65	S	S	*	*	P	Polyproline II helix	trans	-73.9	125.5	-179.6	-170.5	171.2	7.7	0	0	110.1
67	T	88.9	Confident	85.1	Confident	114 Å²	114	122.1 Å²	122.1	70%	0.699	64%	0.639	S	S	*	*	P	Polyproline II helix	trans	-77.4	150.4	171	45.5	0	0	0	0	110.6	K65	K65-T67 PolarHBondContact O-N 3.36Å
68	V	87.9	Confident	85.2	Confident	131 Å²	131	117 Å²	117	79%	0.794	62%	0.615	S	S	*	*	P	Polyproline II helix	trans	-84.1	137.4	174.9	-69.1	0	0	0	0	110.2
69	N	89.9	Confident	85.3	Confident	142 Å²	142	115.4 Å²	115.4	76%	0.759	61%	0.609	S	S	*	*			trans	-92.2	113.3	167	-68.6	-38.3	0	0	0	107.9	S71	N69-S71 PolarHBondContact O-N 3.41Å
70	V	88.7	Confident	85.4	Confident	135 Å²	135	120.1 Å²	120.1	82%	0.818	62%	0.624	S	S	*	*			trans	-72.9	111.9	178.3	-177.5	0	0	0	0	108.3
71	S	86.1	Confident	85.6	Confident	100 Å²	100	115 Å²	115	70%	0.699	62%	0.615	S	S	*	*	P	Polyproline II helix	trans	-103.3	129.7	176.2	-58.5	0	0	0	0	108.8	N69	N69-S71 PolarHBondContact O-N 3.41Å
72	L	84.4	Confident	86.2	Confident	121 Å²	121	108.7 Å²	108.7	63%	0.634	59%	0.588	S	S	*	*	P	Polyproline II helix	trans	-69.4	134.1	175.4	-64.4	173.7	0	0	0	109.7	R225	L72-R225 VanDerWaalsContact CB-NH2 3.32Å
73	M	83.8	Confident	86.7	Confident	148 Å²	148	104.5 Å²	104.5	73%	0.729	57%	0.569	S	S	*	*	P	Polyproline II helix	trans	-64.2	160.1	177.5	-64.5	-66.6	-72.3	0	0	111.6	R225	M73-R225 PolarHBondContact O-NE 2.73Å; M73-R225 PolarHBondContact O-NH2 3.12Å
74	G	86.9	Confident	87.4	Confident	34 Å²	34	95.5 Å²	95.5	35%	0.351	54%	0.537	S	S	.	.			trans	-74.6	-168	171.2	0	0	0	0	0	112.7
75	C	90.3	Very high	88	Confident	28 Å²	28	89.6 Å²	89.6	19%	0.189	52%	0.518	C	S	.	.	P	Polyproline II helix	trans	-69.1	148.4	170.5	-75	0	0	0	0	111.1	A224 S228 L261	C75-A224 PolarHBondContact SG-O 2.8Å; C75-A224 VanDerWaalsContact SG-O 3.33Å; C75-S228 WeakPolarHBondContact CA-OG 3.48Å; C75-L261 HydrophobicContact CB-CD2 4.43Å
76	Q	89.3	Confident	88.6	Confident	91 Å²	91	82.7 Å²	82.7	43%	0.425	49%	0.49	S	S	.	.	P	Polyproline II helix	trans	-69	137.5	170.3	-59.7	-59.3	-32.9	0	0	109.9	S228 E229 R231 T232	Q76-S228 PolarHBondContact N-OG 3.36Å; Q76-E229 HydrophobicContact CG-CG 4.32Å; Q76-R231 PolarHBondContact O-NH2 2.83Å; Q76-R231 VanDerWaalsContact O-NH2 3.11Å; Q76-T232 HydrophobicContact CB-CG2 3.76Å
77	A	88.8	Confident	89.2	Confident	81 Å²	81	83.5 Å²	83.5	67%	0.669	49%	0.491	S	S	*	.	P	Polyproline II helix	trans	-60.3	141.1	176.3	0	0	0	0	0	110.2
78	A	89	Confident	89.5	Confident	18 Å²	18	81.8 Å²	81.8	15%	0.149	47%	0.472	C	S	.	.	P	Polyproline II helix	trans	-62.7	140.2	174.8	0	0	0	0	0	110	F82	A78-F82 HydrophobicContact CB-CB 4.34Å
79	P	88.9	Confident	89.9	Confident	40 Å²	40	75.8 Å²	75.8	26%	0.26	44%	0.435	S	S	.	.	P	Polyproline II helix	trans	-56.6	157	166.9	-22.8	33	0	0	0	111.5	G81 F82 T232	P79-G81 PolarHBondContact O-N 3.26Å; P79-G81 VanDerWaalsContact O-N 3.17Å; P79-F82 HydrophobicContact CB-CB 4.41Å; P79-F82 HydrophobicContact CB-CD2 3.78Å; P79-F82 HydrophobicContact CB-CE2 4.22Å; P79-F82 HydrophobicContact CB-CG 4.08Å; P79-F82 HydrophobicContact CG-CG 4.37Å; P79-F82 WeakPolarHBondContact O-CB 3.32Å; P79-F82 PolarHBondContact O-N 3.05Å; P79-T232 HydrophobicContact CG-CG2 4.48Å
80	Q	85.9	Confident	90.1	Very high	179 Å²	179	77.2 Å²	77.2	84%	0.836	43%	0.43	S	S	*	.	T	Hydrogen-bonded Turn	trans	-58	123.2	-175.5	-168.5	174.5	15.7	0	0	111.4	F82	Q80-F82 WeakPolarHBondContact O-CD2 3.4Å
81	G	86.8	Confident	90.5	Very high	49 Å²	49	75.6 Å²	75.6	51%	0.505	41%	0.414	S	S	.	.	T	Hydrogen-bonded Turn	trans	84.6	-2	-177.6	0	0	0	0	0	115.7	P79	P79-G81 PolarHBondContact O-N 3.26Å; P79-G81 VanDerWaalsContact O-N 3.17Å
82	F	90	Very high	91.1	Very high	19 Å²	19	72.7 Å²	72.7	8%	0.083	39%	0.389	C	S	.	.	T	Hydrogen-bonded Turn	trans	-93.6	-15	176.5	-70.9	-119.7	0	0	0	112.3	A78 P79 Q80 L234 Q237 L242 N246	A78-F82 HydrophobicContact CB-CB 4.34Å; P79-F82 HydrophobicContact CB-CB 4.41Å; P79-F82 HydrophobicContact CB-CD2 3.78Å; P79-F82 HydrophobicContact CB-CE2 4.22Å; P79-F82 HydrophobicContact CB-CG 4.08Å; P79-F82 HydrophobicContact CG-CG 4.37Å; P79-F82 WeakPolarHBondContact O-CB 3.32Å; P79-F82 PolarHBondContact O-N 3.05Å; Q80-F82 WeakPolarHBondContact O-CD2 3.4Å; F82-L234 HydrophobicContact CE1-CB 3.97Å; F82-Q237 HydrophobicContact CD2-CG 3.84Å; F82-Q237 HydrophobicContact CE1-CG 4.31Å; F82-Q237 HydrophobicContact CE2-CG 3.5Å; F82-Q237 VanDerWaalsContact CE2-CG 3.5Å; F82-Q237 HydrophobicContact CG-CG 4.39Å; F82-Q237 HydrophobicContact CZ-CG 3.76Å; F82-L242 HydrophobicContact CB-CD1 4.14Å; F82-L242 HydrophobicContact CB-CD2 4.45Å; F82-L242 HydrophobicContact CD1-CD1 3.7Å; F82-L242 HydrophobicContact CD1-CD2 3.69Å; F82-L242 HydrophobicContact CD1-CG 4.32Å; F82-L242 HydrophobicContact CE1-CD2 4.25Å; F82-L242 HydrophobicContact CG-CD1 4.38Å; F82-L242 HydrophobicContact CG-CD2 4.25Å; F82-N246 PolarHBondContact O-ND2 3Å
83	S	91.3	Very high	91.7	Very high	32 Å²	32	68.5 Å²	68.5	22%	0.224	37%	0.368	C	S	.	.	S	Bend	trans	-70.9	129.8	178.1	-169.5	0	0	0	0	111.2	K264	S83-K264 PolarHBondContact OG-O 3Å
84	P	92.8	Very high	92.3	Very high	15 Å²	15	64.2 Å²	64.2	10%	0.097	35%	0.353	C	S	.	.	P	Polyproline II helix	trans	-77	140.8	176.8	31.7	-34	0	0	0	111.6	W88 Q89 N246	P84-W88 HydrophobicContact CB-CD2 4.15Å; P84-W88 HydrophobicContact CB-CE3 3.5Å; P84-W88 VanDerWaalsContact CB-CE3 3.5Å; P84-W88 HydrophobicContact CB-CZ3 3.83Å; P84-W88 HydrophobicContact CG-CE3 4.14Å; P84-W88 HydrophobicContact CG-CZ3 4.09Å; P84-Q89 HydrophobicContact CB-CG 4.46Å; P84-Q89 HydrophobicContact CG-CG 4.1Å; P84-Q89 PolarHBondContact O-NE2 3.35Å; P84-N246 HydrophobicContact CG-CB 4.15Å
85	S	94.1	Very high	92.8	Very high	59 Å²	59	65.1 Å²	65.1	41%	0.413	35%	0.349	S	S	.	.	P	Polyproline II helix	trans	-56.7	149.5	174.2	69	0	0	0	0	112.8	K87 W88 Q89	S85-K87 PolarHBondContact O-N 3.06Å; S85-W88 WeakPolarHBondContact O-CB 3.4Å; S85-W88 PolarHBondContact O-N 3.04Å; S85-W88 WeakPolarHBondContact OG-CB 3.25Å; S85-W88 PolarHBondContact OG-N 3.28Å; S85-Q89 WeakPolarHBondContact O-CG 3.49Å; S85-Q89 PolarHBondContact O-N 3.28Å
86	L	93.6	Very high	93.2	Very high	40 Å²	40	63.8 Å²	63.8	21%	0.209	34%	0.34	C	S	.	.	H	α-helix	trans	-61.9	-33.9	178.1	-175.2	65.9	0	0	0	111.9	W88 Q89 R90 E265	L86-W88 VanDerWaalsContact C-N 3.34Å; L86-Q89 PolarHBondContact O-N 2.96Å; L86-R90 WeakPolarHBondContact O-CB 3.18Å; L86-R90 VanDerWaalsContact O-CG 3.32Å; L86-R90 WeakPolarHBondContact O-CG 3.32Å; L86-R90 PolarHBondContact O-N 3.27Å; L86-E265 VanDerWaalsContact CB-CD 3.45Å; L86-E265 HydrophobicContact CB-CG 4.1Å; L86-E265 VanDerWaalsContact CB-OE1 3.25Å; L86-E265 WeakPolarHBondContact CB-OE1 3.41Å; L86-E265 PolarHBondContact N-OE1 2.73Å
87	K	95.8	Very high	93.5	Very high	178 Å²	178	62 Å²	62	77%	0.774	34%	0.339	S	S	*	.	H	α-helix	trans	-60.8	-45.3	173.8	-177.4	179.7	177.2	-176.4	0	110.8	S85 Q91	S85-K87 PolarHBondContact O-N 3.06Å; K87-Q91 PolarHBondContact O-N 3.22Å; K87-Q91 VanDerWaalsContact O-N 3.08Å
88	W	95.5	Very high	93.9	Very high	78 Å²	78	62.9 Å²	62.9	30%	0.295	33%	0.328	S	S	.	.	H	α-helix	trans	-63.3	-47	175.8	-178.7	95.6	0	0	0	111	P84 S85 L86 R90 Q91 Q92 N246 L247 C250	P84-W88 HydrophobicContact CB-CD2 4.15Å; P84-W88 HydrophobicContact CB-CE3 3.5Å; P84-W88 VanDerWaalsContact CB-CE3 3.5Å; P84-W88 HydrophobicContact CB-CZ3 3.83Å; P84-W88 HydrophobicContact CG-CE3 4.14Å; P84-W88 HydrophobicContact CG-CZ3 4.09Å; S85-W88 WeakPolarHBondContact O-CB 3.4Å; S85-W88 PolarHBondContact O-N 3.04Å; S85-W88 WeakPolarHBondContact OG-CB 3.25Å; S85-W88 PolarHBondContact OG-N 3.28Å; L86-W88 VanDerWaalsContact C-N 3.34Å; W88-R90 PolarHBondContact O-N 3.26Å; W88-Q91 WeakPolarHBondContact O-CB 3.3Å; W88-Q91 PolarHBondContact O-N 3.2Å; W88-Q91 VanDerWaalsContact O-N 3.12Å; W88-Q92 HydrophobicContact CD2-CG 3.75Å; W88-Q92 HydrophobicContact CE3-CG 3.84Å; W88-Q92 HydrophobicContact CH2-CG 3.75Å; W88-Q92 HydrophobicContact CZ2-CG 3.61Å; W88-Q92 HydrophobicContact CZ3-CG 3.85Å; W88-Q92 WeakPolarHBondContact O-CG 3.48Å; W88-Q92 PolarHBondContact O-N 3.33Å; W88-N246 HydrophobicContact CH2-CB 4.31Å; W88-N246 HydrophobicContact CZ3-CB 4.49Å; W88-L247 HydrophobicContact CH2-CB 4.03Å; W88-L247 HydrophobicContact CH2-CD1 4.31Å; W88-C250 HydrophobicContact CZ3-CB 4.2Å
89	Q	95.6	Very high	94.3	Very high	4 Å²	4	65 Å²	65	2%	0.019	34%	0.337	C	S	.	.	H	α-helix	trans	-55.5	-49.2	178.7	-67.9	-178.7	35.8	0	0	111.6	P84 S85 L86 Q91 Q92 V93 C250 D263	P84-Q89 HydrophobicContact CB-CG 4.46Å; P84-Q89 HydrophobicContact CG-CG 4.1Å; P84-Q89 PolarHBondContact O-NE2 3.35Å; S85-Q89 WeakPolarHBondContact O-CG 3.49Å; S85-Q89 PolarHBondContact O-N 3.28Å; L86-Q89 PolarHBondContact O-N 2.96Å; Q89-Q91 VanDerWaalsContact C-N 3.32Å; Q89-Q91 PolarHBondContact O-N 2.83Å; Q89-Q92 PolarHBondContact O-N 2.91Å; Q89-V93 VanDerWaalsContact O-CG2 3.31Å; Q89-V93 WeakPolarHBondContact O-CG2 3.41Å; Q89-V93 PolarHBondContact O-N 3.36Å; Q89-C250 VanDerWaalsContact CA-SG 3.53Å; Q89-C250 VanDerWaalsContact CB-SG 3.55Å; Q89-C250 HydrophobicContact CG-CB 4.49Å; Q89-D263 PolarHBondContact NE2-O 3.45Å
90	R	95.4	Very high	94.6	Very high	173 Å²	173	64 Å²	64	65%	0.653	33%	0.328	S	S	*	.	H	α-helix	trans	-60.7	-40.8	178	-72.9	174.4	178.4	177.3	1.1	112.3	L86 W88 V93 S94	L86-R90 WeakPolarHBondContact O-CB 3.18Å; L86-R90 VanDerWaalsContact O-CG 3.32Å; L86-R90 WeakPolarHBondContact O-CG 3.32Å; L86-R90 PolarHBondContact O-N 3.27Å; W88-R90 PolarHBondContact O-N 3.26Å; R90-V93 PolarHBondContact O-N 3.34Å; R90-S94 PolarHBondContact O-N 3.11Å
91	Q	97.3	Very high	95	Very high	101 Å²	101	63.2 Å²	63.2	47%	0.472	32%	0.317	S	S	.	.	H	α-helix	trans	-62.9	-43.9	176.7	-172.5	63.4	49	0	0	111.5	K87 W88 Q89 S94 N95	K87-Q91 PolarHBondContact O-N 3.22Å; K87-Q91 VanDerWaalsContact O-N 3.08Å; W88-Q91 WeakPolarHBondContact O-CB 3.3Å; W88-Q91 PolarHBondContact O-N 3.2Å; W88-Q91 VanDerWaalsContact O-N 3.12Å; Q89-Q91 VanDerWaalsContact C-N 3.32Å; Q89-Q91 PolarHBondContact O-N 2.83Å; Q91-S94 WeakPolarHBondContact O-CB 3.31Å; Q91-S94 PolarHBondContact O-N 3.28Å; Q91-N95 PolarHBondContact NE2-OD1 3.15Å; Q91-N95 VanDerWaalsContact O-CG 3.22Å; Q91-N95 PolarHBondContact O-N 3.05Å; Q91-N95 PolarHBondContact O-OD1 2.86Å
92	Q	97.1	Very high	95.4	Very high	38 Å²	38	63.9 Å²	63.9	18%	0.178	31%	0.314	C	S	.	.	H	α-helix	trans	-64.5	-41.7	178.8	-62.4	-47.1	-39.5	0	0	112.2	W88 Q89 S94 N95 F96 L247	W88-Q92 HydrophobicContact CD2-CG 3.75Å; W88-Q92 HydrophobicContact CE3-CG 3.84Å; W88-Q92 HydrophobicContact CH2-CG 3.75Å; W88-Q92 HydrophobicContact CZ2-CG 3.61Å; W88-Q92 HydrophobicContact CZ3-CG 3.85Å; W88-Q92 WeakPolarHBondContact O-CG 3.48Å; W88-Q92 PolarHBondContact O-N 3.33Å; Q89-Q92 PolarHBondContact O-N 2.91Å; Q92-S94 VanDerWaalsContact C-N 3.31Å; Q92-S94 PolarHBondContact O-N 3.02Å; Q92-N95 PolarHBondContact O-N 3.03Å; Q92-F96 VanDerWaalsContact O-CB 3.25Å; Q92-F96 WeakPolarHBondContact O-CB 3.46Å; Q92-F96 PolarHBondContact O-N 3.44Å; Q92-L247 HydrophobicContact CB-CD1 3.82Å; Q92-L247 HydrophobicContact CG-CD1 3.91Å
93	V	96.8	Very high	95.6	Very high	34 Å²	34	63.8 Å²	63.8	21%	0.206	31%	0.314	C	S	.	.	H	α-helix	trans	-60	-42.9	175	172.7	0	0	0	0	111	Q89 R90 S97 R254 Y255	Q89-V93 VanDerWaalsContact O-CG2 3.31Å; Q89-V93 WeakPolarHBondContact O-CG2 3.41Å; Q89-V93 PolarHBondContact O-N 3.36Å; R90-V93 PolarHBondContact O-N 3.34Å; V93-S97 PolarHBondContact O-N 3.31Å; V93-R254 HydrophobicContact CG2-CB 3.55Å; V93-R254 HydrophobicContact CG2-CG 4.45Å; V93-Y255 HydrophobicContact CG1-CD2 3.99Å
94	S	97.6	Very high	95.6	Very high	57 Å²	57	65.9 Å²	65.9	40%	0.399	33%	0.329	S	S	.	.	H	α-helix	trans	-62	-52.7	175.5	-169.7	0	0	0	0	111.5	R90 Q91 Q92 F96 S97 E98	R90-S94 PolarHBondContact O-N 3.11Å; Q91-S94 WeakPolarHBondContact O-CB 3.31Å; Q91-S94 PolarHBondContact O-N 3.28Å; Q92-S94 VanDerWaalsContact C-N 3.31Å; Q92-S94 PolarHBondContact O-N 3.02Å; S94-F96 VanDerWaalsContact C-N 3.27Å; S94-F96 PolarHBondContact O-N 3.45Å; S94-S97 VanDerWaalsContact O-CB 3.32Å; S94-S97 WeakPolarHBondContact O-CB 3.38Å; S94-S97 PolarHBondContact O-N 3.46Å; S94-S97 VanDerWaalsContact O-N 3.11Å; S94-E98 PolarHBondContact O-N 3.22Å; S94-E98 VanDerWaalsContact O-N 3.15Å
95	N	97.7	Very high	95.7	Very high	53 Å²	53	73 Å²	73	28%	0.283	36%	0.358	S	S	.	.	H	α-helix	trans	-57.7	-42.2	179.4	-68.8	-3.9	0	0	0	111.5	Q91 Q92 S97 E98 I99	Q91-N95 PolarHBondContact NE2-OD1 3.15Å; Q91-N95 VanDerWaalsContact O-CG 3.22Å; Q91-N95 PolarHBondContact O-N 3.05Å; Q91-N95 PolarHBondContact O-OD1 2.86Å; Q92-N95 PolarHBondContact O-N 3.03Å; N95-S97 VanDerWaalsContact C-N 3.34Å; N95-S97 PolarHBondContact O-N 2.71Å; N95-E98 PolarHBondContact O-N 3.12Å; N95-I99 WeakPolarHBondContact O-CG1 3.28Å; N95-I99 PolarHBondContact O-N 2.86Å
96	F	97.5	Very high	95.6	Very high	0 Å²	0	73.5 Å²	73.5	0%	0	35%	0.354	C	S	.	.	H	α-helix	trans	-64.5	-38.8	178.6	-173	-111.1	0	0	0	112.1	Q92 S94 E98 I99 R100 Y202 L205 A206 L251 Y255 F256	Q92-F96 VanDerWaalsContact O-CB 3.25Å; Q92-F96 WeakPolarHBondContact O-CB 3.46Å; Q92-F96 PolarHBondContact O-N 3.44Å; S94-F96 VanDerWaalsContact C-N 3.27Å; S94-F96 PolarHBondContact O-N 3.45Å; F96-E98 VanDerWaalsContact C-N 3.31Å; F96-E98 PolarHBondContact O-N 3.4Å; F96-I99 PolarHBondContact O-N 2.89Å; F96-R100 HydrophobicContact CD1-CG 4.36Å; F96-R100 HydrophobicContact CE1-CG 4.15Å; F96-R100 HydrophobicContact CZ-CG 4.23Å; F96-R100 WeakPolarHBondContact O-CB 3.22Å; F96-R100 VanDerWaalsContact O-CG 3.31Å; F96-R100 WeakPolarHBondContact O-CG 3.26Å; F96-R100 PolarHBondContact O-N 2.99Å; F96-Y202 HydrophobicContact CD2-CE1 4.27Å; F96-Y202 AromaticContact CD2-CE2 3.77Å; F96-Y202 HydrophobicContact CD2-CE2 3.77Å; F96-Y202 AromaticContact CD2-CZ 3.61Å; F96-Y202 HydrophobicContact CE2-CD2 4.43Å; F96-Y202 HydrophobicContact CE2-CE1 4.37Å; F96-Y202 HydrophobicContact CE2-CE2 4.07Å; F96-L205 HydrophobicContact CE2-CB 4.49Å; F96-L205 HydrophobicContact CZ-CB 3.93Å; F96-A206 HydrophobicContact CE2-CB 3.82Å; F96-A206 HydrophobicContact CZ-CB 4.19Å; F96-L251 HydrophobicContact CB-CD2 3.62Å; F96-L251 HydrophobicContact CD1-CD1 4.43Å; F96-L251 HydrophobicContact CD1-CD2 3.8Å; F96-L251 HydrophobicContact CD2-CD1 3.76Å; F96-L251 HydrophobicContact CD2-CD2 4.14Å; F96-L251 HydrophobicContact CE1-CD1 4.45Å; F96-L251 HydrophobicContact CE1-CD2 4.43Å; F96-L251 HydrophobicContact CE2-CD1 3.79Å; F96-L251 HydrophobicContact CG-CD1 4.07Å; F96-L251 HydrophobicContact CG-CD2 3.6Å; F96-L251 HydrophobicContact CG-CG 4.47Å; F96-L251 HydrophobicContact CZ-CD1 4.14Å; F96-Y255 AromaticContact CD1-CD1 3.6Å; F96-Y255 HydrophobicContact CD1-CD1 3.6Å; F96-Y255 AromaticContact CD1-CD2 3.61Å; F96-Y255 HydrophobicContact CD1-CD2 3.61Å; F96-Y255 AromaticContact CD1-CE1 3.75Å; F96-Y255 HydrophobicContact CD1-CE1 3.75Å; F96-Y255 AromaticContact CD1-CE2 3.76Å; F96-Y255 HydrophobicContact CD1-CE2 3.76Å; F96-Y255 AromaticContact CD1-CG 3.53Å; F96-Y255 HydrophobicContact CD1-CG 3.53Å; F96-Y255 AromaticContact CD1-CZ 3.83Å; F96-Y255 AromaticContact CE1-CD1 3.44Å; F96-Y255 HydrophobicContact CE1-CD1 3.44Å; F96-Y255 VanDerWaalsContact CE1-CD1 3.44Å; F96-Y255 HydrophobicContact CE1-CD2 4.32Å; F96-Y255 AromaticContact CE1-CE1 3.54Å; F96-Y255 HydrophobicContact CE1-CE1 3.54Å; F96-Y255 HydrophobicContact CE1-CE2 4.41Å; F96-Y255 AromaticContact CE1-CG 3.86Å; F96-Y255 HydrophobicContact CE1-CG 3.86Å; F96-F256 HydrophobicContact CE1-CE2 4.01Å; F96-F256 HydrophobicContact CE1-CZ 4.04Å; F96-F256 HydrophobicContact CZ-CE2 4.31Å; F96-F256 HydrophobicContact CZ-CZ 4.31Å
97	S	96.8	Very high	95.5	Very high	55 Å²	55	73.9 Å²	73.9	39%	0.385	35%	0.352	S	S	.	.	H	α-helix	trans	-59	-43.1	173	-168.3	0	0	0	0	112	V93 S94 N95 R100 R101	V93-S97 PolarHBondContact O-N 3.31Å; S94-S97 VanDerWaalsContact O-CB 3.32Å; S94-S97 WeakPolarHBondContact O-CB 3.38Å; S94-S97 PolarHBondContact O-N 3.46Å; S94-S97 VanDerWaalsContact O-N 3.11Å; N95-S97 VanDerWaalsContact C-N 3.34Å; N95-S97 PolarHBondContact O-N 2.71Å; S97-R100 PolarHBondContact O-N 2.96Å; S97-R101 WeakPolarHBondContact O-CB 3.46Å; S97-R101 PolarHBondContact O-N 3.1Å
98	E	97.3	Very high	95.2	Very high	98 Å²	98	72.6 Å²	72.6	46%	0.458	35%	0.353	S	S	.	.	H	α-helix	trans	-65.9	-42.4	178.2	-62.2	-174.4	164.6	0	0	112.5	S94 N95 F96 R100 R101 S102	S94-E98 PolarHBondContact O-N 3.22Å; S94-E98 VanDerWaalsContact O-N 3.15Å; N95-E98 PolarHBondContact O-N 3.12Å; F96-E98 VanDerWaalsContact C-N 3.31Å; F96-E98 PolarHBondContact O-N 3.4Å; E98-R100 VanDerWaalsContact C-N 3.34Å; E98-R100 PolarHBondContact O-N 3.03Å; E98-R101 PolarHBondContact O-N 3.46Å; E98-S102 WeakPolarHBondContact O-CB 3.42Å; E98-S102 PolarHBondContact O-N 3.15Å
99	I	96	Very high	95.1	Very high	62 Å²	62	74.2 Å²	74.2	32%	0.318	36%	0.364	S	S	.	.	H	α-helix	trans	-59.4	-48	175.9	-73.1	164.6	0	0	0	109.9	N95 F96 R101 S102 I103 Y202 A206	N95-I99 WeakPolarHBondContact O-CG1 3.28Å; N95-I99 PolarHBondContact O-N 2.86Å; F96-I99 PolarHBondContact O-N 2.89Å; I99-R101 PolarHBondContact O-N 2.88Å; I99-S102 WeakPolarHBondContact O-CB 3.23Å; I99-S102 PolarHBondContact O-N 3.39Å; I99-S102 VanDerWaalsContact O-N 3.13Å; I99-I103 HydrophobicContact CG2-CD1 3.78Å; I99-I103 HydrophobicContact CG2-CG1 4.42Å; I99-I103 WeakPolarHBondContact O-CG1 3.16Å; I99-I103 PolarHBondContact O-N 2.8Å; I99-Y202 HydrophobicContact CD1-CE1 4.27Å; I99-Y202 WeakPolarHBondContact CD1-OH 3.39Å; I99-A206 HydrophobicContact CG2-CB 4.4Å
100	R	95.4	Very high	94.8	Very high	20 Å²	20	77.5 Å²	77.5	8%	0.075	38%	0.376	C	S	.	.	H	α-helix	trans	-61.5	-44.6	178.1	-72.5	-173.1	50.5	122.5	7.5	112.4	F96 S97 E98 S102 I103 S104 L205 A206 L208 Y255	F96-R100 HydrophobicContact CD1-CG 4.36Å; F96-R100 HydrophobicContact CE1-CG 4.15Å; F96-R100 HydrophobicContact CZ-CG 4.23Å; F96-R100 WeakPolarHBondContact O-CB 3.22Å; F96-R100 VanDerWaalsContact O-CG 3.31Å; F96-R100 WeakPolarHBondContact O-CG 3.26Å; F96-R100 PolarHBondContact O-N 2.99Å; S97-R100 PolarHBondContact O-N 2.96Å; E98-R100 VanDerWaalsContact C-N 3.34Å; E98-R100 PolarHBondContact O-N 3.03Å; R100-S102 VanDerWaalsContact C-N 3.26Å; R100-S102 PolarHBondContact O-N 2.98Å; R100-I103 PolarHBondContact O-N 2.72Å; R100-S104 WeakPolarHBondContact O-CB 3.49Å; R100-S104 PolarHBondContact O-N 2.73Å; R100-S104 PolarHBondContact O-OG 3.14Å; R100-S104 VanDerWaalsContact O-OG 3.11Å; R100-L205 PolarHBondContact NH1-O 3.24Å; R100-A206 HydrophobicContact CG-CB 4.1Å; R100-A206 WeakPolarHBondContact CG-O 3.47Å; R100-L208 PolarHBondContact NH1-O 3.06Å; R100-L208 PolarHBondContact NH2-O 3.11Å; R100-Y255 VanDerWaalsContact CD-OH 3.23Å; R100-Y255 WeakPolarHBondContact CD-OH 3.34Å; R100-Y255 PolarHBondContact NE-OH 3.49Å; R100-Y255 VanDerWaalsContact NE-OH 3.16Å
101	R	94.8	Very high	94.4	Very high	163 Å²	163	71 Å²	71	62%	0.615	36%	0.357	S	S	*	.	H	α-helix	trans	-57.9	-41.6	174.2	-177	-179.1	63.8	-154	-4	111.4	S97 E98 I99 K105	S97-R101 WeakPolarHBondContact O-CB 3.46Å; S97-R101 PolarHBondContact O-N 3.1Å; E98-R101 PolarHBondContact O-N 3.46Å; I99-R101 PolarHBondContact O-N 2.88Å; R101-K105 VanDerWaalsContact O-CB 3.24Å; R101-K105 WeakPolarHBondContact O-CB 3.31Å; R101-K105 PolarHBondContact O-N 3.11Å
102	S	95.2	Very high	93.8	Very high	62 Å²	62	69.1 Å²	69.1	43%	0.434	37%	0.365	S	S	.	.	H	α-helix	trans	-64.8	-48	177	-169.5	0	0	0	0	111.9	E98 I99 R100 S104 K105 H106	E98-S102 WeakPolarHBondContact O-CB 3.42Å; E98-S102 PolarHBondContact O-N 3.15Å; I99-S102 WeakPolarHBondContact O-CB 3.23Å; I99-S102 PolarHBondContact O-N 3.39Å; I99-S102 VanDerWaalsContact O-N 3.13Å; R100-S102 VanDerWaalsContact C-N 3.26Å; R100-S102 PolarHBondContact O-N 2.98Å; S102-S104 PolarHBondContact O-N 2.69Å; S102-K105 PolarHBondContact O-N 3.17Å; S102-H106 PolarHBondContact O-CD2 3.32Å; S102-H106 VanDerWaalsContact O-CD2 3.28Å; S102-H106 PolarHBondContact O-N 2.93Å
103	I	93.6	Very high	93.4	Very high	17 Å²	17	70.6 Å²	70.6	9%	0.087	37%	0.372	C	S	.	.	H	α-helix	trans	-58.6	-50	177.5	-67.2	168.2	0	0	0	110.1	I99 R100 K105 H106 R107 L166 A206	I99-I103 HydrophobicContact CG2-CD1 3.78Å; I99-I103 HydrophobicContact CG2-CG1 4.42Å; I99-I103 WeakPolarHBondContact O-CG1 3.16Å; I99-I103 PolarHBondContact O-N 2.8Å; R100-I103 PolarHBondContact O-N 2.72Å; I103-K105 VanDerWaalsContact C-N 3.33Å; I103-K105 PolarHBondContact O-N 3.19Å; I103-H106 PolarHBondContact O-N 3.17Å; I103-R107 WeakPolarHBondContact O-CA 3.38Å; I103-R107 WeakPolarHBondContact O-CB 3.25Å; I103-R107 PolarHBondContact O-N 2.98Å; I103-L166 HydrophobicContact CD1-CD2 4.42Å; I103-L166 HydrophobicContact CG1-CD2 3.88Å; I103-A206 HydrophobicContact CD1-CB 3.65Å
104	S	92	Very high	92.6	Very high	76 Å²	76	73.5 Å²	73.5	53%	0.531	40%	0.4	S	S	.	.	H	α-helix	trans	-60.5	-41.3	178.5	-60.6	0	0	0	0	112.2	R100 S102	R100-S104 WeakPolarHBondContact O-CB 3.49Å; R100-S104 PolarHBondContact O-N 2.73Å; R100-S104 PolarHBondContact O-OG 3.14Å; R100-S104 VanDerWaalsContact O-OG 3.11Å; S102-S104 PolarHBondContact O-N 2.69Å
105	K	94.1	Very high	91.9	Very high	165 Å²	165	72.8 Å²	72.8	72%	0.717	39%	0.391	S	S	*	.	H	α-helix	trans	-64.6	-40.5	179.2	-179	-179.3	176.4	-172.5	0	112.6	R101 S102 I103	R101-K105 VanDerWaalsContact O-CB 3.24Å; R101-K105 WeakPolarHBondContact O-CB 3.31Å; R101-K105 PolarHBondContact O-N 3.11Å; S102-K105 PolarHBondContact O-N 3.17Å; I103-K105 VanDerWaalsContact C-N 3.33Å; I103-K105 PolarHBondContact O-N 3.19Å
106	H	92.8	Very high	90.9	Very high	70 Å²	70	76.1 Å²	76.1	32%	0.324	41%	0.409	S	S	.	.	H	α-helix	trans	-101	7.7	-174.3	-65.2	-86	0	0	0	113.4	S102 I103 L108 H109 W110	S102-H106 PolarHBondContact O-CD2 3.32Å; S102-H106 VanDerWaalsContact O-CD2 3.28Å; S102-H106 PolarHBondContact O-N 2.93Å; I103-H106 PolarHBondContact O-N 3.17Å; H106-L108 PolarHBondContact O-N 3.42Å; H106-H109 WeakPolarHBondContact O-CB 3.47Å; H106-H109 PolarHBondContact O-N 2.94Å; H106-H109 VanDerWaalsContact O-N 3.09Å; H106-W110 PolarHBondContact O-N 3.46Å; H106-W110 VanDerWaalsContact O-N 3.08Å
107	R	91.6	Very high	89.7	Confident	47 Å²	47	83.7 Å²	83.7	18%	0.177	45%	0.45	C	S	.	.	H	α-helix	trans	-54.4	-49.4	-173.9	-168.4	174.9	-173.8	135.5	11.3	113.1	I103 H109 W110 S111 S170 L172 E209	I103-R107 WeakPolarHBondContact O-CA 3.38Å; I103-R107 WeakPolarHBondContact O-CB 3.25Å; I103-R107 PolarHBondContact O-N 2.98Å; R107-H109 VanDerWaalsContact C-N 3.3Å; R107-H109 PolarHBondContact O-N 3.15Å; R107-W110 PolarHBondContact O-N 2.96Å; R107-S111 WeakPolarHBondContact O-CB 3.49Å; R107-S111 PolarHBondContact O-N 3.16Å; R107-S111 PolarHBondContact O-OG 3.35Å; R107-S111 VanDerWaalsContact O-OG 3.13Å; R107-S170 PolarHBondContact NE-O 3.34Å; R107-L172 PolarHBondContact NH2-O 3.5Å; R107-E209 IonicContact CZ-OE1 3.88Å; R107-E209 IonicContact NH1-OE1 2.95Å; R107-E209 PolarHBondContact NH1-OE1 3.49Å
108	L	89.8	Confident	88.8	Confident	152 Å²	152	87.3 Å²	87.3	80%	0.796	46%	0.464	S	S	*	.	H	α-helix	trans	-64	-36.1	-179.8	-66.7	176	0	0	0	112.5	H106 S111 G112	H106-L108 PolarHBondContact O-N 3.42Å; L108-S111 WeakPolarHBondContact CA-OG 3.4Å; L108-S111 PolarHBondContact O-OG 3.03Å; L108-S111 VanDerWaalsContact O-OG 3.08Å; L108-G112 PolarHBondContact O-N 3.21Å
109	H	92.1	Very high	88.1	Confident	111 Å²	111	83.6 Å²	83.6	51%	0.514	45%	0.449	S	S	.	.	H	α-helix	trans	-64.5	-49.5	177.8	174.4	73.9	0	0	0	110.6	H106 R107 G112 Q113	H106-H109 WeakPolarHBondContact O-CB 3.47Å; H106-H109 PolarHBondContact O-N 2.94Å; H106-H109 VanDerWaalsContact O-N 3.09Å; R107-H109 VanDerWaalsContact C-N 3.3Å; R107-H109 PolarHBondContact O-N 3.15Å; H109-G112 PolarHBondContact O-N 3.43Å; H109-Q113 PolarHBondContact NE2-NE2 3.41Å
110	W	89.9	Confident	87.6	Confident	73 Å²	73	87.5 Å²	87.5	28%	0.277	47%	0.469	S	S	.	.	H	α-helix	trans	-71.8	-34.7	-179	-65.6	117.1	0	0	0	113.2	H106 R107 G112 Q113 L166	H106-W110 PolarHBondContact O-N 3.46Å; H106-W110 VanDerWaalsContact O-N 3.08Å; R107-W110 PolarHBondContact O-N 2.96Å; W110-G112 PolarHBondContact O-N 2.94Å; W110-Q113 VanDerWaalsContact CE3-CD 3.47Å; W110-Q113 VanDerWaalsContact CE3-NE2 3.32Å; W110-Q113 VanDerWaalsContact CE3-OE1 3.24Å; W110-Q113 VanDerWaalsContact CZ3-OE1 3.25Å; W110-Q113 PolarHBondContact O-N 3.44Å; W110-L166 HydrophobicContact CB-CB 4.32Å; W110-L166 HydrophobicContact CD2-CB 3.85Å; W110-L166 HydrophobicContact CD2-CD1 4.39Å; W110-L166 HydrophobicContact CE3-CB 4.32Å; W110-L166 HydrophobicContact CG-CB 3.82Å; W110-L166 HydrophobicContact CZ2-CD1 4.11Å
111	S	87.4	Confident	87.2	Confident	37 Å²	37	89.8 Å²	89.8	26%	0.259	48%	0.482	S	S	.	.	H	α-helix	trans	-67.8	-22.6	176	63.8	0	0	0	0	113.3	R107 L108 R171	R107-S111 WeakPolarHBondContact O-CB 3.49Å; R107-S111 PolarHBondContact O-N 3.16Å; R107-S111 PolarHBondContact O-OG 3.35Å; R107-S111 VanDerWaalsContact O-OG 3.13Å; L108-S111 WeakPolarHBondContact CA-OG 3.4Å; L108-S111 PolarHBondContact O-OG 3.03Å; L108-S111 VanDerWaalsContact O-OG 3.08Å; S111-R171 PolarHBondContact O-NH1 2.86Å; S111-R171 PolarHBondContact O-NH2 3.47Å; S111-R171 VanDerWaalsContact O-NH2 3.08Å
112	G	84.9	Confident	87	Confident	62 Å²	62	83.1 Å²	83.1	64%	0.639	46%	0.459	S	S	*	.	T	Hydrogen-bonded Turn	trans	-86.1	-14.1	179.6	0	0	0	0	0	115	L108 H109 W110	L108-G112 PolarHBondContact O-N 3.21Å; H109-G112 PolarHBondContact O-N 3.43Å; W110-G112 PolarHBondContact O-N 2.94Å
113	Q	87.5	Confident	86.8	Confident	69 Å²	69	88.2 Å²	88.2	32%	0.322	47%	0.474	S	S	.	.	S	Bend	trans	-75.2	133.3	-179.1	-70.1	-175.9	0.7	0	0	111.4	H109 W110 L115 R171	H109-Q113 PolarHBondContact NE2-NE2 3.41Å; W110-Q113 VanDerWaalsContact CE3-CD 3.47Å; W110-Q113 VanDerWaalsContact CE3-NE2 3.32Å; W110-Q113 VanDerWaalsContact CE3-OE1 3.24Å; W110-Q113 VanDerWaalsContact CZ3-OE1 3.25Å; W110-Q113 PolarHBondContact O-N 3.44Å; Q113-L115 PolarHBondContact O-N 3.29Å; Q113-R171 PolarHBondContact O-NH2 3.4Å
114	A	81.2	Confident	86.6	Confident	95 Å²	95	90.8 Å²	90.8	79%	0.785	49%	0.485	S	S	*	.	P	Polyproline II helix	trans	-54.2	138.1	174.5	0	0	0	0	0	110.9
115	L	81.9	Confident	86.6	Confident	42 Å²	42	93.5 Å²	93.5	22%	0.22	49%	0.494	C	S	.	.	P	Polyproline II helix	trans	-85.7	150.8	169.6	-63.8	175.9	0	0	0	108.2	Q113 V119 M121 I168	Q113-L115 PolarHBondContact O-N 3.29Å; L115-V119 HydrophobicContact CB-CB 4.16Å; L115-V119 HydrophobicContact CD1-CB 4.42Å; L115-V119 HydrophobicContact CD1-CG1 4.06Å; L115-M121 HydrophobicContact CD1-CG 4.36Å; L115-M121 HydrophobicContact CD1-SD 4.11Å; L115-I168 HydrophobicContact CD2-CG1 4.35Å
116	D	77.1	Confident	86.6	Confident	123 Å²	123	86.7 Å²	86.7	66%	0.658	47%	0.468	S	S	*	.	P	Polyproline II helix	trans	-61.1	147.3	169.9	-61	-29.2	0	0	0	109.6	N118 V119	D116-N118 PolarHBondContact O-N 3.47Å; D116-V119 HydrophobicContact CB-CG2 4.34Å; D116-V119 PolarHBondContact O-N 3.01Å
117	D	72.8	Confident	86.6	Confident	159 Å²	159	86.3 Å²	86.3	85%	0.85	47%	0.467	S	S	*	.	T	Hydrogen-bonded Turn	trans	-55.5	-23.3	-177.1	-70.2	-23.9	0	0	0	113.1	V119	D117-V119 VanDerWaalsContact C-N 3.3Å; D117-V119 PolarHBondContact O-N 3.11Å
118	N	78.3	Confident	86.6	Confident	130 Å²	130	87.9 Å²	87.9	70%	0.695	48%	0.476	S	S	*	.	T	Hydrogen-bonded Turn	trans	-76.9	-12.6	179.8	-61.4	-14.9	0	0	0	113.4	D116 L120 F162	D116-N118 PolarHBondContact O-N 3.47Å; N118-L120 PolarHBondContact O-N 2.91Å; N118-F162 WeakPolarHBondContact O-CZ 3.49Å
119	V	82.5	Confident	86.7	Confident	21 Å²	21	86.1 Å²	86.1	13%	0.127	46%	0.464	C	S	.	.			trans	-92.4	88.9	-176.8	-171.5	0	0	0	0	110.5	L115 D116 D117 F133 F162 I168	L115-V119 HydrophobicContact CB-CB 4.16Å; L115-V119 HydrophobicContact CD1-CB 4.42Å; L115-V119 HydrophobicContact CD1-CG1 4.06Å; D116-V119 HydrophobicContact CB-CG2 4.34Å; D116-V119 PolarHBondContact O-N 3.01Å; D117-V119 VanDerWaalsContact C-N 3.3Å; D117-V119 PolarHBondContact O-N 3.11Å; V119-F133 HydrophobicContact CG1-CE2 4.22Å; V119-F133 HydrophobicContact CG1-CZ 4.11Å; V119-F162 HydrophobicContact CB-CE1 4.47Å; V119-F162 HydrophobicContact CG2-CD1 4.29Å; V119-F162 HydrophobicContact CG2-CE1 3.76Å; V119-F162 HydrophobicContact CG2-CZ 4.45Å; V119-I168 HydrophobicContact CG1-CD1 4.28Å; V119-I168 HydrophobicContact CG1-CG1 4.33Å
120	L	84.5	Confident	86.8	Confident	143 Å²	143	80.9 Å²	80.9	75%	0.749	44%	0.439	S	S	*	.			trans	-93	103.1	172.5	-63.2	175.9	0	0	0	110.2	N118 P122	N118-L120 PolarHBondContact O-N 2.91Å; L120-P122 WeakPolarHBondContact O-CD 3.32Å
121	M	87.1	Confident	86.9	Confident	69 Å²	69	78.3 Å²	78.3	34%	0.34	43%	0.43	S	S	.	.	P	Polyproline II helix	trans	-69.3	124.7	178.3	-67.1	-172.6	70.4	0	0	111	L115 W130 I168 R171 L172	L115-M121 HydrophobicContact CD1-CG 4.36Å; L115-M121 HydrophobicContact CD1-SD 4.11Å; M121-W130 HydrophobicContact CE-CH2 4.22Å; M121-I168 HydrophobicContact CE-CG2 4.38Å; M121-R171 HydrophobicContact CE-CB 4.33Å; M121-R171 HydrophobicContact SD-CB 4.32Å; M121-L172 HydrophobicContact CE-CD2 3.34Å; M121-L172 HydrophobicContact CE-CG 4.35Å
122	P	91.2	Very high	87	Confident	22 Å²	22	80.2 Å²	80.2	14%	0.143	43%	0.434	C	S	.	.	P	Polyproline II helix	trans	-63.9	160.1	176.2	-20.7	32.5	0	0	0	112.7	L120 A126 Q129 W130 F133	L120-P122 WeakPolarHBondContact O-CD 3.32Å; P122-A126 HydrophobicContact CB-CB 4.46Å; P122-Q129 HydrophobicContact CB-CB 3.82Å; P122-Q129 HydrophobicContact CG-CB 4.08Å; P122-W130 HydrophobicContact CB-CD2 4.03Å; P122-W130 HydrophobicContact CB-CG 4.19Å; P122-W130 HydrophobicContact CB-CZ2 4.22Å; P122-W130 HydrophobicContact CG-CD2 3.99Å; P122-W130 HydrophobicContact CG-CE3 4.19Å; P122-W130 HydrophobicContact CG-CG 4.37Å; P122-W130 HydrophobicContact CG-CZ2 4.47Å; P122-W130 WeakPolarHBondContact O-CZ2 3.39Å; P122-F133 HydrophobicContact CG-CB 3.93Å; P122-F133 HydrophobicContact CG-CD2 4.23Å; P122-F133 HydrophobicContact CG-CG 4.13Å
123	K	91.3	Very high	87.4	Confident	170 Å²	170	78 Å²	78	74%	0.739	41%	0.407	S	S	*	.	P	Polyproline II helix	trans	-69.9	153.3	170	-66.8	-175.9	179.4	-179.3	0	110.1	D125 A126 W130	K123-D125 VanDerWaalsContact C-N 3.28Å; K123-D125 PolarHBondContact O-N 3.32Å; K123-A126 HydrophobicContact CB-CB 4.4Å; K123-A126 WeakPolarHBondContact O-CB 3.34Å; K123-A126 PolarHBondContact O-N 3.5Å; K123-A126 VanDerWaalsContact O-N 3.09Å; K123-W130 PolarHBondContact O-NE1 3.24Å
124	Q	89.4	Confident	87.6	Confident	71 Å²	71	74.8 Å²	74.8	33%	0.332	39%	0.391	S	S	.	.	T	Hydrogen-bonded Turn	trans	-51.8	-45.5	-178.6	-175.6	-179	-54.4	0	0	112.6	A126 T176 A179 Y183	Q124-A126 PolarHBondContact O-N 3.49Å; Q124-T176 PolarHBondContact OE1-OG1 3Å; Q124-A179 HydrophobicContact CG-CB 4.25Å; Q124-Y183 WeakPolarHBondContact O-CE2 3.47Å; Q124-Y183 PolarHBondContact O-OH 2.97Å
125	D	91.2	Very high	88	Confident	133 Å²	133	70.2 Å²	70.2	71%	0.711	35%	0.354	S	S	*	.	T	Hydrogen-bonded Turn	trans	-81.6	0.7	-174.1	-47.7	-42.5	0	0	0	114	K123 E127	K123-D125 VanDerWaalsContact C-N 3.28Å; K123-D125 PolarHBondContact O-N 3.32Å; D125-E127 PolarHBondContact O-N 2.93Å; D125-E127 VanDerWaalsContact O-N 3.15Å
126	A	93.8	Very high	88.3	Confident	21 Å²	21	68.2 Å²	68.2	17%	0.174	34%	0.344	C	S	.	.			trans	-90.6	69.8	-174.8	0	0	0	0	0	111.6	P122 K123 Q124 E128 Q129 W130	P122-A126 HydrophobicContact CB-CB 4.46Å; K123-A126 HydrophobicContact CB-CB 4.4Å; K123-A126 WeakPolarHBondContact O-CB 3.34Å; K123-A126 PolarHBondContact O-N 3.5Å; K123-A126 VanDerWaalsContact O-N 3.09Å; Q124-A126 PolarHBondContact O-N 3.49Å; A126-E128 PolarHBondContact O-N 3.3Å; A126-Q129 HydrophobicContact CB-CB 3.91Å; A126-Q129 HydrophobicContact CB-CG 4.06Å; A126-Q129 VanDerWaalsContact CB-OE1 3.25Å; A126-Q129 PolarHBondContact O-N 3.24Å; A126-Q129 VanDerWaalsContact O-N 3.09Å; A126-W130 PolarHBondContact O-N 3.11Å
127	E	93.1	Very high	88.5	Confident	63 Å²	63	66 Å²	66	29%	0.294	33%	0.329	S	S	.	.	H	α-helix	trans	-48.2	-53.7	-176.7	175.2	170.1	-177.4	0	0	113.4	D125 Q129 W130 K131 Y183	D125-E127 PolarHBondContact O-N 2.93Å; D125-E127 VanDerWaalsContact O-N 3.15Å; E127-Q129 VanDerWaalsContact C-N 3.28Å; E127-Q129 PolarHBondContact O-N 3.4Å; E127-W130 PolarHBondContact O-N 2.97Å; E127-K131 HydrophobicContact CG-CD 4.25Å; E127-K131 WeakPolarHBondContact O-CG 3.43Å; E127-K131 PolarHBondContact O-N 3.29Å; E127-K131 WeakPolarHBondContact OE1-CE 3.42Å; E127-K131 IonicContact OE1-NZ 3.17Å; E127-K131 PolarHBondContact OE1-NZ 3.44Å; E127-Y183 HydrophobicContact CB-CD1 3.84Å; E127-Y183 HydrophobicContact CB-CD2 4.18Å; E127-Y183 HydrophobicContact CB-CE1 3.79Å; E127-Y183 HydrophobicContact CB-CE2 4.13Å; E127-Y183 HydrophobicContact CB-CG 4.05Å; E127-Y183 HydrophobicContact CG-CD1 3.5Å; E127-Y183 HydrophobicContact CG-CD2 4.27Å; E127-Y183 HydrophobicContact CG-CE1 3.96Å; E127-Y183 HydrophobicContact CG-CG 3.69Å
128	E	91.4	Very high	88.8	Confident	80 Å²	80	60.6 Å²	60.6	37%	0.374	30%	0.3	S	S	.	.	H	α-helix	trans	-67.2	-29.8	-176.8	-61.4	-52.3	146.5	0	0	113.2	A126 K131 K132 Y140	A126-E128 PolarHBondContact O-N 3.3Å; E128-K131 IonicContact OE1-NZ 2.69Å; E128-K131 PolarHBondContact OE1-NZ 2.89Å; E128-K131 VanDerWaalsContact OE1-NZ 3.15Å; E128-K131 IonicContact OE2-NZ 3.39Å; E128-K132 WeakPolarHBondContact O-CG 3.4Å; E128-K132 PolarHBondContact O-N 3.36Å; E128-K132 VanDerWaalsContact O-N 3.15Å; E128-Y140 WeakPolarHBondContact OE2-CE2 3.35Å; E128-Y140 PolarHBondContact OE2-OH 3.41Å
129	Q	91.8	Very high	88.7	Confident	114 Å²	114	55.8 Å²	55.8	53%	0.533	28%	0.275	S	S	.	.	H	α-helix	trans	-72.5	-38	175.6	-64.2	177.8	-5.4	0	0	110.7	P122 A126 E127 K132 F133	P122-Q129 HydrophobicContact CB-CB 3.82Å; P122-Q129 HydrophobicContact CG-CB 4.08Å; A126-Q129 HydrophobicContact CB-CB 3.91Å; A126-Q129 HydrophobicContact CB-CG 4.06Å; A126-Q129 VanDerWaalsContact CB-OE1 3.25Å; A126-Q129 PolarHBondContact O-N 3.24Å; A126-Q129 VanDerWaalsContact O-N 3.09Å; E127-Q129 VanDerWaalsContact C-N 3.28Å; E127-Q129 PolarHBondContact O-N 3.4Å; Q129-K132 PolarHBondContact O-N 3.42Å; Q129-F133 WeakPolarHBondContact O-CB 3.09Å; Q129-F133 PolarHBondContact O-N 2.81Å
130	W	93.9	Very high	88.4	Confident	2 Å²	2	57.1 Å²	57.1	1%	0.008	28%	0.279	C	S	.	.	H	α-helix	trans	-64.8	-42.9	174	-82.1	112.9	0	0	0	112.6	M121 P122 K123 A126 E127 K132 F133 C134 L172 T176 V180 Y183	M121-W130 HydrophobicContact CE-CH2 4.22Å; P122-W130 HydrophobicContact CB-CD2 4.03Å; P122-W130 HydrophobicContact CB-CG 4.19Å; P122-W130 HydrophobicContact CB-CZ2 4.22Å; P122-W130 HydrophobicContact CG-CD2 3.99Å; P122-W130 HydrophobicContact CG-CE3 4.19Å; P122-W130 HydrophobicContact CG-CG 4.37Å; P122-W130 HydrophobicContact CG-CZ2 4.47Å; P122-W130 WeakPolarHBondContact O-CZ2 3.39Å; K123-W130 PolarHBondContact O-NE1 3.24Å; A126-W130 PolarHBondContact O-N 3.11Å; E127-W130 PolarHBondContact O-N 2.97Å; W130-K132 PolarHBondContact O-N 3.33Å; W130-F133 HydrophobicContact CE3-CD1 4.1Å; W130-F133 AromaticContact CZ3-CD1 3.95Å; W130-F133 HydrophobicContact CZ3-CD1 3.95Å; W130-F133 HydrophobicContact CZ3-CE1 4.21Å; W130-F133 PolarHBondContact O-N 2.98Å; W130-C134 WeakPolarHBondContact O-CB 3.46Å; W130-C134 PolarHBondContact O-N 3.38Å; W130-C134 PolarHBondContact O-SG 2.63Å; W130-L172 HydrophobicContact CH2-CD2 3.63Å; W130-L172 HydrophobicContact CZ2-CD2 4.33Å; W130-L172 HydrophobicContact CZ3-CD2 4.39Å; W130-T176 HydrophobicContact CH2-CG2 4.31Å; W130-T176 HydrophobicContact CZ2-CG2 3.73Å; W130-V180 HydrophobicContact CB-CG2 4.45Å; W130-V180 HydrophobicContact CD2-CG1 4.43Å; W130-V180 HydrophobicContact CD2-CG2 3.41Å; W130-V180 VanDerWaalsContact CD2-CG2 3.41Å; W130-V180 HydrophobicContact CE3-CG1 4.13Å; W130-V180 HydrophobicContact CE3-CG2 3.71Å; W130-V180 HydrophobicContact CG-CG2 3.76Å; W130-V180 HydrophobicContact CH2-CG2 4.36Å; W130-V180 HydrophobicContact CZ2-CG2 4.1Å; W130-V180 HydrophobicContact CZ3-CG2 4.17Å; W130-Y183 HydrophobicContact CB-CD2 4.06Å; W130-Y183 AromaticContact CD1-CE2 3.98Å; W130-Y183 HydrophobicContact CG-CD2 4.32Å
131	K	92.2	Very high	87.9	Confident	19 Å²	19	54.8 Å²	54.8	8%	0.083	27%	0.267	C	S	.	.	H	α-helix	trans	-58.6	-47.8	175.7	-69.5	171.3	-176.6	168.2	0	111.1	E127 E128 C134 L135 Y140 Y183 W187	E127-K131 HydrophobicContact CG-CD 4.25Å; E127-K131 WeakPolarHBondContact O-CG 3.43Å; E127-K131 PolarHBondContact O-N 3.29Å; E127-K131 WeakPolarHBondContact OE1-CE 3.42Å; E127-K131 IonicContact OE1-NZ 3.17Å; E127-K131 PolarHBondContact OE1-NZ 3.44Å; E128-K131 IonicContact OE1-NZ 2.69Å; E128-K131 PolarHBondContact OE1-NZ 2.89Å; E128-K131 VanDerWaalsContact OE1-NZ 3.15Å; E128-K131 IonicContact OE2-NZ 3.39Å; K131-C134 PolarHBondContact O-N 3.01Å; K131-L135 VanDerWaalsContact O-CB 3.3Å; K131-L135 WeakPolarHBondContact O-CB 3.42Å; K131-L135 WeakPolarHBondContact O-CG 3.36Å; K131-L135 PolarHBondContact O-N 2.93Å; K131-Y140 HydrophobicContact CB-CD2 3.88Å; K131-Y140 HydrophobicContact CB-CE2 3.89Å; K131-Y140 HydrophobicContact CD-CE2 4.08Å; K131-Y183 WeakPolarHBondContact CE-O 3.39Å; K131-W187 HydrophobicContact CD-CB 4.37Å; K131-W187 HydrophobicContact CD-CG 4.5Å
132	K	91.1	Very high	87	Confident	76 Å²	76	57 Å²	57	33%	0.33	28%	0.28	S	S	.	.	H	α-helix	trans	-64.8	-41.1	175.9	-70.7	178.8	-179.6	-168.1	0	112.8	E128 Q129 W130 C134 G136 Y140	E128-K132 WeakPolarHBondContact O-CG 3.4Å; E128-K132 PolarHBondContact O-N 3.36Å; E128-K132 VanDerWaalsContact O-N 3.15Å; Q129-K132 PolarHBondContact O-N 3.42Å; W130-K132 PolarHBondContact O-N 3.33Å; K132-C134 PolarHBondContact O-N 2.97Å; K132-G136 WeakPolarHBondContact O-CA 3.27Å; K132-G136 PolarHBondContact O-N 2.99Å; K132-Y140 HydrophobicContact CD-CD1 4.42Å; K132-Y140 HydrophobicContact CG-CD1 3.87Å; K132-Y140 HydrophobicContact CG-CD2 4.25Å; K132-Y140 HydrophobicContact CG-CE1 4.27Å; K132-Y140 HydrophobicContact CG-CG 3.88Å
133	F	92.2	Very high	85.4	Confident	16 Å²	16	58.6 Å²	58.6	7%	0.07	29%	0.291	C	S	.	.	H	α-helix	trans	-61.2	-44.8	178.5	-178.7	-89.9	0	0	0	111.6	V119 P122 Q129 W130 F162 I168 W200	V119-F133 HydrophobicContact CG1-CE2 4.22Å; V119-F133 HydrophobicContact CG1-CZ 4.11Å; P122-F133 HydrophobicContact CG-CB 3.93Å; P122-F133 HydrophobicContact CG-CD2 4.23Å; P122-F133 HydrophobicContact CG-CG 4.13Å; Q129-F133 WeakPolarHBondContact O-CB 3.09Å; Q129-F133 PolarHBondContact O-N 2.81Å; W130-F133 HydrophobicContact CE3-CD1 4.1Å; W130-F133 AromaticContact CZ3-CD1 3.95Å; W130-F133 HydrophobicContact CZ3-CD1 3.95Å; W130-F133 HydrophobicContact CZ3-CE1 4.21Å; W130-F133 PolarHBondContact O-N 2.98Å; F133-F162 HydrophobicContact CD1-CB 4.35Å; F133-F162 AromaticContact CD2-CD2 3.6Å; F133-F162 HydrophobicContact CD2-CD2 3.6Å; F133-F162 HydrophobicContact CD2-CE2 4.07Å; F133-F162 HydrophobicContact CD2-CG 4.38Å; F133-F162 HydrophobicContact CE1-CB 3.9Å; F133-F162 HydrophobicContact CE1-CD2 4.46Å; F133-F162 HydrophobicContact CE1-CG 4.37Å; F133-F162 HydrophobicContact CE2-CB 4.29Å; F133-F162 AromaticContact CE2-CD2 3.44Å; F133-F162 HydrophobicContact CE2-CD2 3.44Å; F133-F162 VanDerWaalsContact CE2-CD2 3.44Å; F133-F162 AromaticContact CE2-CE2 3.88Å; F133-F162 HydrophobicContact CE2-CE2 3.88Å; F133-F162 AromaticContact CE2-CG 3.87Å; F133-F162 HydrophobicContact CE2-CG 3.87Å; F133-F162 HydrophobicContact CG-CD2 4.19Å; F133-F162 HydrophobicContact CZ-CB 3.86Å; F133-F162 AromaticContact CZ-CD2 3.91Å; F133-F162 HydrophobicContact CZ-CD2 3.91Å; F133-F162 AromaticContact CZ-CG 3.86Å; F133-F162 HydrophobicContact CZ-CG 3.86Å; F133-F162 PolarHBondContact O-N 2.9Å; F133-I168 HydrophobicContact CE1-CG2 4.2Å; F133-I168 HydrophobicContact CZ-CD1 4.25Å; F133-I168 HydrophobicContact CZ-CG2 4.3Å; F133-W200 HydrophobicContact CD1-CH2 4.39Å; F133-W200 HydrophobicContact CD1-CZ2 4.21Å; F133-W200 AromaticContact CE1-CH2 3.94Å; F133-W200 HydrophobicContact CE1-CH2 3.94Å; F133-W200 AromaticContact CE1-CZ2 3.94Å; F133-W200 HydrophobicContact CE1-CZ2 3.94Å
134	C	92.4	Very high	83.7	Confident	1 Å²	1	55.3 Å²	55.3	1%	0.007	29%	0.287	C	S	.	.	H	α-helix	trans	-78.7	-40.2	-176.7	-65	0	0	0	0	113.5	W130 K131 K132 L184 W200	W130-C134 WeakPolarHBondContact O-CB 3.46Å; W130-C134 PolarHBondContact O-N 3.38Å; W130-C134 PolarHBondContact O-SG 2.63Å; K131-C134 PolarHBondContact O-N 3.01Å; K132-C134 PolarHBondContact O-N 2.97Å; C134-L184 HydrophobicContact CB-CD1 4.48Å; C134-L184 HydrophobicContact CB-CD2 4.03Å; C134-W200 HydrophobicContact CB-CD2 3.96Å; C134-W200 HydrophobicContact CB-CG 3.9Å; C134-W200 HydrophobicContact CB-CZ2 4.45Å; C134-W200 PolarHBondContact O-NE1 2.85Å; C134-W200 VanDerWaalsContact O-NE1 3.12Å
135	L	89.9	Confident	82.1	Confident	0 Å²	0	56.9 Å²	56.9	0%	0	30%	0.303	C	S	.	.	H	α-helix	trans	-104.2	-18.9	-170	-55.4	177.1	0	0	0	113.7	K131 V139 L184 W187 V194 Q196 L197	K131-L135 VanDerWaalsContact O-CB 3.3Å; K131-L135 WeakPolarHBondContact O-CB 3.42Å; K131-L135 WeakPolarHBondContact O-CG 3.36Å; K131-L135 PolarHBondContact O-N 2.93Å; L135-V139 HydrophobicContact CB-CB 4.24Å; L135-V139 HydrophobicContact CB-CG1 4.23Å; L135-V139 WeakPolarHBondContact O-CB 3.39Å; L135-V139 WeakPolarHBondContact O-CG2 3.46Å; L135-L184 HydrophobicContact CD1-CD2 4.37Å; L135-L184 HydrophobicContact CG-CD2 4.32Å; L135-W187 HydrophobicContact CD1-CD2 3.49Å; L135-W187 VanDerWaalsContact CD1-CD2 3.49Å; L135-W187 HydrophobicContact CD1-CE3 3.69Å; L135-W187 HydrophobicContact CD1-CG 4.08Å; L135-W187 HydrophobicContact CD1-CH2 3.99Å; L135-W187 HydrophobicContact CD1-CZ2 3.8Å; L135-W187 HydrophobicContact CD1-CZ3 3.94Å; L135-V194 HydrophobicContact CD2-CG2 4.28Å; L135-Q196 HydrophobicContact CD2-CB 4.35Å; L135-L197 HydrophobicContact CD2-CB 3.85Å; L135-L197 HydrophobicContact CD2-CD1 4.19Å
136	G	87.6	Confident	80.3	Confident	0 Å²	0	54.8 Å²	54.8	0%	0	30%	0.296	C	S	.	.	H	α-helix	trans	81.6	159.8	-173.8	0	0	0	0	0	113.5	K132 N138 Y140 K159 G161	K132-G136 WeakPolarHBondContact O-CA 3.27Å; K132-G136 PolarHBondContact O-N 2.99Å; G136-N138 VanDerWaalsContact C-N 3.3Å; G136-N138 PolarHBondContact O-N 3.25Å; G136-Y140 WeakPolarHBondContact O-CB 3.49Å; G136-Y140 PolarHBondContact O-N 3.33Å; G136-Y140 VanDerWaalsContact O-N 3.07Å; G136-K159 CarbonylContact C-O 3.19Å; G136-K159 WeakPolarHBondContact CA-O 3.5Å; G136-G161 VanDerWaalsContact CA-CA 3.43Å; G136-G161 VanDerWaalsContact N-CA 3.29Å
137	E	82	Confident	78.1	Confident	76 Å²	76	61 Å²	61	36%	0.355	33%	0.326	S	S	.	.	H	α-helix	trans	-64	-33.1	177.8	-69	-165.6	151.7	0	0	113.1	V139 Y140 L141 V158 K159	E137-V139 PolarHBondContact O-N 3.35Å; E137-Y140 PolarHBondContact O-N 3.47Å; E137-L141 HydrophobicContact CB-CD1 4.33Å; E137-L141 VanDerWaalsContact O-CB 3.26Å; E137-L141 WeakPolarHBondContact O-CB 3.5Å; E137-L141 WeakPolarHBondContact O-CG 3.4Å; E137-L141 PolarHBondContact O-N 2.79Å; E137-V158 PolarHBondContact N-O 2.98Å; E137-K159 PolarHBondContact N-O 2.74Å
138	N	77.3	Confident	75.9	Confident	45 Å²	45	65.1 Å²	65.1	24%	0.241	35%	0.345	C	S	.	.	H	α-helix	trans	-62.9	-47.4	-178.1	-67.1	-14.3	0	0	0	111.7	G136 N142 S143 K159	G136-N138 VanDerWaalsContact C-N 3.3Å; G136-N138 PolarHBondContact O-N 3.25Å; N138-N142 WeakPolarHBondContact O-CA 3.09Å; N138-N142 PolarHBondContact O-N 3.39Å; N138-N142 VanDerWaalsContact O-N 3.16Å; N138-S143 PolarHBondContact O-N 3.27Å; N138-S143 VanDerWaalsContact O-N 3.14Å; N138-K159 WeakPolarHBondContact CB-O 3.49Å; N138-K159 VanDerWaalsContact CG-O 3.32Å; N138-K159 PolarHBondContact N-O 3.36Å; N138-K159 VanDerWaalsContact N-O 3.1Å; N138-K159 PolarHBondContact ND2-O 3.43Å
139	V	76.7	Confident	73.7	Confident	29 Å²	29	67.6 Å²	67.6	18%	0.176	37%	0.365	C	S	.	.	H	α-helix	trans	-74	-38	179.2	179.9	0	0	0	0	110.8	L135 E137 N142 W187 V194	L135-V139 HydrophobicContact CB-CB 4.24Å; L135-V139 HydrophobicContact CB-CG1 4.23Å; L135-V139 WeakPolarHBondContact O-CB 3.39Å; L135-V139 WeakPolarHBondContact O-CG2 3.46Å; E137-V139 PolarHBondContact O-N 3.35Å; V139-N142 PolarHBondContact O-OD1 3.03Å; V139-W187 HydrophobicContact CG1-CH2 3.76Å; V139-W187 HydrophobicContact CG1-CZ2 3.89Å; V139-V194 HydrophobicContact CG1-CG1 4.1Å; V139-V194 HydrophobicContact CG1-CG2 4.1Å
140	Y	75.5	Confident	71.5	Confident	50 Å²	50	66.8 Å²	66.8	20%	0.196	37%	0.368	C	S	.	.	H	α-helix	trans	-69.9	-41.6	-178.3	-179.2	-91.4	0	0	0	112.7	E128 K131 K132 G136 E137	E128-Y140 WeakPolarHBondContact OE2-CE2 3.35Å; E128-Y140 PolarHBondContact OE2-OH 3.41Å; K131-Y140 HydrophobicContact CB-CD2 3.88Å; K131-Y140 HydrophobicContact CB-CE2 3.89Å; K131-Y140 HydrophobicContact CD-CE2 4.08Å; K132-Y140 HydrophobicContact CD-CD1 4.42Å; K132-Y140 HydrophobicContact CG-CD1 3.87Å; K132-Y140 HydrophobicContact CG-CD2 4.25Å; K132-Y140 HydrophobicContact CG-CE1 4.27Å; K132-Y140 HydrophobicContact CG-CG 3.88Å; G136-Y140 WeakPolarHBondContact O-CB 3.49Å; G136-Y140 PolarHBondContact O-N 3.33Å; G136-Y140 VanDerWaalsContact O-N 3.07Å; E137-Y140 PolarHBondContact O-N 3.47Å
141	L	74.9	Confident	69.3	Low	94 Å²	94	76.2 Å²	76.2	49%	0.492	41%	0.413	S	S	.	.	T	Hydrogen-bonded Turn	trans	-90.5	-1.4	-179.2	-62.7	174.5	0	0	0	113.8	E137 S143	E137-L141 HydrophobicContact CB-CD1 4.33Å; E137-L141 VanDerWaalsContact O-CB 3.26Å; E137-L141 WeakPolarHBondContact O-CB 3.5Å; E137-L141 WeakPolarHBondContact O-CG 3.4Å; E137-L141 PolarHBondContact O-N 2.79Å; L141-S143 PolarHBondContact O-N 3.33Å; L141-S143 VanDerWaalsContact O-N 3.16Å
142	N	67.9	Low	67.3	Low	116 Å²	116	81.2 Å²	81.2	62%	0.62	44%	0.44	S	S	*	.	T	Hydrogen-bonded Turn	trans	49.8	32.3	-168.4	-60.2	-20.3	0	0	0	112.8	N138 V139 R191	N138-N142 WeakPolarHBondContact O-CA 3.09Å; N138-N142 PolarHBondContact O-N 3.39Å; N138-N142 VanDerWaalsContact O-N 3.16Å; V139-N142 PolarHBondContact O-OD1 3.03Å; N142-R191 PolarHBondContact ND2-NH1 2.99Å; N142-R191 PolarHBondContact OD1-NH1 3.31Å; N142-R191 VanDerWaalsContact OD1-NH1 3.1Å
143	S	58.6	Low	65.5	Low	54 Å²	54	84 Å²	84	38%	0.378	47%	0.466	S	S	.	.	P	Polyproline II helix	trans	-77.2	135.6	179.5	-72.2	0	0	0	0	109.4	N138 L141	N138-S143 PolarHBondContact O-N 3.27Å; N138-S143 VanDerWaalsContact O-N 3.14Å; L141-S143 PolarHBondContact O-N 3.33Å; L141-S143 VanDerWaalsContact O-N 3.16Å
144	P	55.3	Low	64	Low	101 Å²	101	85.7 Å²	85.7	66%	0.656	49%	0.488	S	S	*	.	P	Polyproline II helix	trans	-58.7	147.5	174	25.1	-32.1	0	0	0	109.3	T146	P144-T146 PolarHBondContact O-N 3.38Å
145	P	55.7	Low	62.7	Low	104 Å²	104	91.6 Å²	91.6	68%	0.675	52%	0.519	S	S	*	.	P	Polyproline II helix	trans	-54.8	116.3	175.3	22.9	-31.2	0	0	0	108.1	D147	P145-D147 PolarHBondContact O-N 3.28Å
146	T	52.3	Low	62.1	Low	89 Å²	89	94.8 Å²	94.8	55%	0.546	54%	0.536	S	S	.	.			trans	-77	109.2	176.8	5.3	0	0	0	0	107.2	P144 H148	P144-T146 PolarHBondContact O-N 3.38Å; T146-H148 PolarHBondContact O-N 3.37Å
147	D	47.8	Very low	61.6	Low	151 Å²	151	98.2 Å²	98.2	81%	0.807	55%	0.549	S	S	*	.			trans	-66.2	26.9	172.7	-76.6	-27	0	0	0	113.3	P145 V149	P145-D147 PolarHBondContact O-N 3.28Å; D147-V149 VanDerWaalsContact C-N 3.29Å; D147-V149 PolarHBondContact O-N 2.87Å
148	H	47.8	Very low	61.3	Low	150 Å²	150	98.5 Å²	98.5	69%	0.694	56%	0.556	S	S	*	*			trans	-79.9	88.2	168.5	-72.1	-60.5	0	0	0	108.1	T146 T150	T146-H148 PolarHBondContact O-N 3.37Å; H148-T150 PolarHBondContact O-N 3.28Å; H148-T150 PolarHBondContact O-OG1 3.23Å
149	V	44.5	Very low	61.3	Low	133 Å²	133	99.7 Å²	99.7	81%	0.806	56%	0.559	S	S	*	*			trans	-49	95.4	162.1	-174.4	0	0	0	0	106.8	D147	D147-V149 VanDerWaalsContact C-N 3.29Å; D147-V149 PolarHBondContact O-N 2.87Å
150	T	46.3	Very low	61.5	Low	97 Å²	97	101.4 Å²	101.4	60%	0.595	57%	0.569	S	S	*	*			trans	-76.7	129.4	167.7	-20.6	0	0	0	0	103.9	H148 D152	H148-T150 PolarHBondContact O-N 3.28Å; H148-T150 PolarHBondContact O-OG1 3.23Å; T150-D152 PolarHBondContact O-N 3.46Å
151	E	48.1	Very low	62.1	Low	200 Å²	200	99.3 Å²	99.3	94%	0.935	56%	0.563	S	S	*	*	S	Bend	trans	-68.2	26	-169	-62.2	-178	150.2	0	0	114.6
152	D	48.5	Very low	62.8	Low	124 Å²	124	95.5 Å²	95.5	66%	0.663	54%	0.543	S	S	*	.			trans	-119.2	122.1	175.5	-158	2	0	0	0	109.1	T150 G154	T150-D152 PolarHBondContact O-N 3.46Å; D152-G154 PolarHBondContact O-N 3.13Å
153	P	53.8	Low	64	Low	134 Å²	134	91.6 Å²	91.6	87%	0.87	52%	0.523	S	S	*	.			trans	-66.3	0.1	179.3	-16.6	30	0	0	0	114.2
154	G	60	Low	65.6	Low	52 Å²	52	90.3 Å²	90.3	54%	0.536	51%	0.514	S	S	.	.	S	Bend	trans	-71.2	132.2	179	0	0	0	0	0	112.6	D152 D156	D152-G154 PolarHBondContact O-N 3.13Å; G154-D156 PolarHBondContact O-N 3.36Å
155	L	66.1	Low	67.4	Low	125 Å²	125	89.8 Å²	89.8	65%	0.654	50%	0.502	S	S	*	.			trans	-63.6	118.7	170.3	-83.5	133.8	0	0	0	110.2	Y157	L155-Y157 HydrophobicContact CB-CE2 4.43Å; L155-Y157 PolarHBondContact O-N 2.88Å; L155-Y157 VanDerWaalsContact O-N 3.09Å
156	D	77.3	Confident	69.1	Low	66 Å²	66	88 Å²	88	35%	0.353	49%	0.486	S	S	.	.			trans	-79.2	91.2	173	-172.1	-7.8	0	0	0	110.4	G154 V158 K159 V160	G154-D156 PolarHBondContact O-N 3.36Å; D156-V158 PolarHBondContact O-N 2.97Å; D156-V158 VanDerWaalsContact OD1-CB 3.27Å; D156-V158 WeakPolarHBondContact OD1-CB 3.48Å; D156-V158 PolarHBondContact OD1-N 2.7Å; D156-K159 HydrophobicContact CB-CB 4.47Å; D156-K159 HydrophobicContact CB-CD 4.21Å; D156-K159 HydrophobicContact CB-CG 4.44Å; D156-K159 PolarHBondContact O-N 3.39Å; D156-K159 VanDerWaalsContact O-N 3.14Å; D156-K159 WeakPolarHBondContact OD2-CD 3.33Å; D156-K159 WeakPolarHBondContact OD2-CE 3.47Å; D156-K159 WeakPolarHBondContact OD2-CG 3.45Å; D156-K159 IonicContact OD2-NZ 3.46Å; D156-K159 PolarHBondContact OD2-NZ 2.9Å; D156-V160 PolarHBondContact O-N 3.11Å; D156-V160 VanDerWaalsContact O-N 3.13Å
157	Y	77.3	Confident	71	Confident	73 Å²	73	85 Å²	85	29%	0.286	47%	0.468	S	S	.	.	H	α-helix	trans	-63.7	-16.2	177.9	-68.2	-68.7	0	0	0	113.7	L155 G161 F162 P163	L155-Y157 HydrophobicContact CB-CE2 4.43Å; L155-Y157 PolarHBondContact O-N 2.88Å; L155-Y157 VanDerWaalsContact O-N 3.09Å; Y157-G161 CarbonylContact O-C 3.52Å; Y157-G161 WeakPolarHBondContact O-CA 3.5Å; Y157-G161 PolarHBondContact O-N 2.66Å; Y157-F162 HydrophobicContact CD1-CD1 4.27Å; Y157-F162 HydrophobicContact CD2-CD1 4.28Å; Y157-F162 AromaticContact CD2-CE1 3.95Å; Y157-F162 HydrophobicContact CD2-CE1 3.95Å; Y157-F162 AromaticContact CG-CD1 3.81Å; Y157-F162 HydrophobicContact CG-CD1 3.81Å; Y157-F162 AromaticContact CG-CE1 3.77Å; Y157-F162 HydrophobicContact CG-CE1 3.77Å; Y157-F162 HydrophobicContact CG-CG 4.46Å; Y157-F162 HydrophobicContact CG-CZ 4.4Å; Y157-P163 HydrophobicContact CE1-CG 4.18Å
158	V	75.9	Confident	73.1	Confident	81 Å²	81	77.9 Å²	77.9	49%	0.491	43%	0.43	S	S	.	.	H	α-helix	trans	-69.5	-40.7	173.9	-174.8	0	0	0	0	110	E137 D156	E137-V158 PolarHBondContact N-O 2.98Å; D156-V158 PolarHBondContact O-N 2.97Å; D156-V158 VanDerWaalsContact OD1-CB 3.27Å; D156-V158 WeakPolarHBondContact OD1-CB 3.48Å; D156-V158 PolarHBondContact OD1-N 2.7Å
159	K	77.4	Confident	75.3	Confident	71 Å²	71	70.8 Å²	70.8	31%	0.309	40%	0.398	S	S	.	.	H	α-helix	trans	-76.8	-42.9	179.1	-67.8	175.4	-175.3	163.5	0	112.8	G136 E137 N138 D156	G136-K159 CarbonylContact C-O 3.19Å; G136-K159 WeakPolarHBondContact CA-O 3.5Å; E137-K159 PolarHBondContact N-O 2.74Å; N138-K159 WeakPolarHBondContact CB-O 3.49Å; N138-K159 VanDerWaalsContact CG-O 3.32Å; N138-K159 PolarHBondContact N-O 3.36Å; N138-K159 VanDerWaalsContact N-O 3.1Å; N138-K159 PolarHBondContact ND2-O 3.43Å; D156-K159 HydrophobicContact CB-CB 4.47Å; D156-K159 HydrophobicContact CB-CD 4.21Å; D156-K159 HydrophobicContact CB-CG 4.44Å; D156-K159 PolarHBondContact O-N 3.39Å; D156-K159 VanDerWaalsContact O-N 3.14Å; D156-K159 WeakPolarHBondContact OD2-CD 3.33Å; D156-K159 WeakPolarHBondContact OD2-CE 3.47Å; D156-K159 WeakPolarHBondContact OD2-CG 3.45Å; D156-K159 IonicContact OD2-NZ 3.46Å; D156-K159 PolarHBondContact OD2-NZ 2.9Å
160	V	80.8	Confident	77.6	Confident	64 Å²	64	64.7 Å²	64.7	39%	0.388	36%	0.361	S	S	.	.	H	α-helix	trans	-93.5	-20.1	-171.8	-173.8	0	0	0	0	113.2	D156	D156-V160 PolarHBondContact O-N 3.11Å; D156-V160 VanDerWaalsContact O-N 3.13Å
161	G	87	Confident	79.8	Confident	7 Å²	7	64.7 Å²	64.7	7%	0.072	35%	0.35	C	S	.	.			trans	92.6	143.9	-174.7	0	0	0	0	0	112.1	G136 Y157	G136-G161 VanDerWaalsContact CA-CA 3.43Å; G136-G161 VanDerWaalsContact N-CA 3.29Å; Y157-G161 CarbonylContact O-C 3.52Å; Y157-G161 WeakPolarHBondContact O-CA 3.5Å; Y157-G161 PolarHBondContact O-N 2.66Å
162	F	90.4	Very high	81.9	Confident	14 Å²	14	55.4 Å²	55.4	6%	0.061	31%	0.306	C	S	.	.			trans	-73.5	132.1	174.8	-73.2	-85.5	0	0	0	109.8	N118 V119 F133 Y157 I168 W200	N118-F162 WeakPolarHBondContact O-CZ 3.49Å; V119-F162 HydrophobicContact CB-CE1 4.47Å; V119-F162 HydrophobicContact CG2-CD1 4.29Å; V119-F162 HydrophobicContact CG2-CE1 3.76Å; V119-F162 HydrophobicContact CG2-CZ 4.45Å; F133-F162 HydrophobicContact CD1-CB 4.35Å; F133-F162 AromaticContact CD2-CD2 3.6Å; F133-F162 HydrophobicContact CD2-CD2 3.6Å; F133-F162 HydrophobicContact CD2-CE2 4.07Å; F133-F162 HydrophobicContact CD2-CG 4.38Å; F133-F162 HydrophobicContact CE1-CB 3.9Å; F133-F162 HydrophobicContact CE1-CD2 4.46Å; F133-F162 HydrophobicContact CE1-CG 4.37Å; F133-F162 HydrophobicContact CE2-CB 4.29Å; F133-F162 AromaticContact CE2-CD2 3.44Å; F133-F162 HydrophobicContact CE2-CD2 3.44Å; F133-F162 VanDerWaalsContact CE2-CD2 3.44Å; F133-F162 AromaticContact CE2-CE2 3.88Å; F133-F162 HydrophobicContact CE2-CE2 3.88Å; F133-F162 AromaticContact CE2-CG 3.87Å; F133-F162 HydrophobicContact CE2-CG 3.87Å; F133-F162 HydrophobicContact CG-CD2 4.19Å; F133-F162 HydrophobicContact CZ-CB 3.86Å; F133-F162 AromaticContact CZ-CD2 3.91Å; F133-F162 HydrophobicContact CZ-CD2 3.91Å; F133-F162 AromaticContact CZ-CG 3.86Å; F133-F162 HydrophobicContact CZ-CG 3.86Å; F133-F162 PolarHBondContact O-N 2.9Å; Y157-F162 HydrophobicContact CD1-CD1 4.27Å; Y157-F162 HydrophobicContact CD2-CD1 4.28Å; Y157-F162 AromaticContact CD2-CE1 3.95Å; Y157-F162 HydrophobicContact CD2-CE1 3.95Å; Y157-F162 AromaticContact CG-CD1 3.81Å; Y157-F162 HydrophobicContact CG-CD1 3.81Å; Y157-F162 AromaticContact CG-CE1 3.77Å; Y157-F162 HydrophobicContact CG-CE1 3.77Å; Y157-F162 HydrophobicContact CG-CG 4.46Å; Y157-F162 HydrophobicContact CG-CZ 4.4Å; F162-I168 HydrophobicContact CB-CD1 4.46Å; F162-W200 VanDerWaalsContact O-CE2 3.26Å; F162-W200 VanDerWaalsContact O-CZ2 3.28Å; F162-W200 WeakPolarHBondContact O-CZ2 3.5Å; F162-W200 PolarHBondContact O-NE1 3.33Å
163	P	92.1	Very high	84	Confident	33 Å²	33	53.6 Å²	53.6	21%	0.214	30%	0.297	C	S	.	.			trans	-73.4	158.7	170.2	32.7	-36.3	0	0	0	110.6	Y157 F165	Y157-P163 HydrophobicContact CE1-CG 4.18Å; P163-F165 HydrophobicContact CB-CE1 4.39Å; P163-F165 HydrophobicContact CB-CZ 4.42Å; P163-F165 HydrophobicContact CG-CD1 4.07Å; P163-F165 HydrophobicContact CG-CD2 3.91Å; P163-F165 HydrophobicContact CG-CE1 3.54Å; P163-F165 HydrophobicContact CG-CE2 3.38Å; P163-F165 HydrophobicContact CG-CG 4.24Å; P163-F165 HydrophobicContact CG-CZ 3.18Å; P163-F165 PolarHBondContact O-N 3.3Å
164	P	93.9	Very high	85.9	Confident	27 Å²	27	49.6 Å²	49.6	18%	0.175	27%	0.267	C	S	.	.			trans	-76.5	69.9	-178.8	32.1	-36.8	0	0	0	111.9	V169 R199 W200 A203	P164-V169 HydrophobicContact CB-CG1 3.82Å; P164-R199 HydrophobicContact CG-CB 4.11Å; P164-W200 HydrophobicContact CB-CD2 3.78Å; P164-W200 HydrophobicContact CB-CE3 3.78Å; P164-W200 HydrophobicContact CB-CG 4.39Å; P164-W200 HydrophobicContact CB-CH2 4.13Å; P164-W200 HydrophobicContact CB-CZ2 4.14Å; P164-W200 HydrophobicContact CB-CZ3 3.95Å; P164-W200 HydrophobicContact CG-CD2 4.32Å; P164-W200 HydrophobicContact CG-CG 4.45Å; P164-A203 HydrophobicContact CB-CB 3.45Å; P164-A203 VanDerWaalsContact CB-CB 3.45Å; P164-A203 HydrophobicContact CG-CB 3.76Å
165	F	92.8	Very high	87.5	Confident	91 Å²	91	49.6 Å²	49.6	40%	0.399	26%	0.261	S	S	.	.			trans	-64.5	148.7	175.8	-65	-51.1	0	0	0	111.5	P163 S167 I168 V169	P163-F165 HydrophobicContact CB-CE1 4.39Å; P163-F165 HydrophobicContact CB-CZ 4.42Å; P163-F165 HydrophobicContact CG-CD1 4.07Å; P163-F165 HydrophobicContact CG-CD2 3.91Å; P163-F165 HydrophobicContact CG-CE1 3.54Å; P163-F165 HydrophobicContact CG-CE2 3.38Å; P163-F165 HydrophobicContact CG-CG 4.24Å; P163-F165 HydrophobicContact CG-CZ 3.18Å; P163-F165 PolarHBondContact O-N 3.3Å; F165-S167 PolarHBondContact O-N 3.41Å; F165-I168 HydrophobicContact CB-CD1 4.18Å; F165-I168 HydrophobicContact CB-CG1 4.28Å; F165-I168 HydrophobicContact CD2-CD1 3.98Å; F165-I168 WeakPolarHBondContact O-CA 3.24Å; F165-I168 WeakPolarHBondContact O-CB 3.37Å; F165-I168 PolarHBondContact O-N 3.19Å; F165-V169 PolarHBondContact O-N 3.28Å
166	L	91.8	Very high	88.9	Confident	67 Å²	67	44.3 Å²	44.3	35%	0.351	23%	0.234	S	C	.	.	H	α-helix	trans	-58.4	-34.6	176.8	-69.4	176.5	0	0	0	112.4	I103 W110 I168 V169 S170	I103-L166 HydrophobicContact CD1-CD2 4.42Å; I103-L166 HydrophobicContact CG1-CD2 3.88Å; W110-L166 HydrophobicContact CB-CB 4.32Å; W110-L166 HydrophobicContact CD2-CB 3.85Å; W110-L166 HydrophobicContact CD2-CD1 4.39Å; W110-L166 HydrophobicContact CE3-CB 4.32Å; W110-L166 HydrophobicContact CG-CB 3.82Å; W110-L166 HydrophobicContact CZ2-CD1 4.11Å; L166-I168 PolarHBondContact O-N 3.04Å; L166-V169 HydrophobicContact CD2-CG2 4.37Å; L166-S170 WeakPolarHBondContact O-CB 3.45Å; L166-S170 PolarHBondContact O-N 3.06Å; L166-S170 VanDerWaalsContact O-N 3.09Å; L166-S170 PolarHBondContact O-OG 3.1Å
167	S	91.1	Very high	89.7	Confident	25 Å²	25	41.1 Å²	41.1	18%	0.175	22%	0.217	C	C	.	.	H	α-helix	trans	-61.9	-28.5	174.1	54	0	0	0	0	113	F165 R171	F165-S167 PolarHBondContact O-N 3.41Å; S167-R171 WeakPolarHBondContact O-CD 3.36Å; S167-R171 VanDerWaalsContact O-CG 3.32Å; S167-R171 WeakPolarHBondContact O-CG 3.35Å; S167-R171 PolarHBondContact O-NE 3.02Å
168	I	92.3	Very high	90.6	Very high	1 Å²	1	39.3 Å²	39.3	1%	0.005	22%	0.215	C	C	.	.	H	α-helix	trans	-88.2	-59.4	178	-58.8	170.8	0	0	0	109.9	L115 V119 M121 F133 F162 F165 L166 S170 R171 W200	L115-I168 HydrophobicContact CD2-CG1 4.35Å; V119-I168 HydrophobicContact CG1-CD1 4.28Å; V119-I168 HydrophobicContact CG1-CG1 4.33Å; M121-I168 HydrophobicContact CE-CG2 4.38Å; F133-I168 HydrophobicContact CE1-CG2 4.2Å; F133-I168 HydrophobicContact CZ-CD1 4.25Å; F133-I168 HydrophobicContact CZ-CG2 4.3Å; F162-I168 HydrophobicContact CB-CD1 4.46Å; F165-I168 HydrophobicContact CB-CD1 4.18Å; F165-I168 HydrophobicContact CB-CG1 4.28Å; F165-I168 HydrophobicContact CD2-CD1 3.98Å; F165-I168 WeakPolarHBondContact O-CA 3.24Å; F165-I168 WeakPolarHBondContact O-CB 3.37Å; F165-I168 PolarHBondContact O-N 3.19Å; L166-I168 PolarHBondContact O-N 3.04Å; I168-S170 VanDerWaalsContact C-N 3.27Å; I168-S170 PolarHBondContact O-N 3.21Å; I168-R171 WeakPolarHBondContact O-CB 3.48Å; I168-R171 PolarHBondContact O-N 3.44Å; I168-W200 HydrophobicContact CG2-CH2 4.13Å
169	V	94.1	Very high	91.5	Very high	2 Å²	2	36 Å²	36	1%	0.012	20%	0.196	C	C	.	.	H	α-helix	trans	-66.4	-28	-171.2	-59.4	0	0	0	0	113.1	P164 F165 L166 R171 L172 W200 A203	P164-V169 HydrophobicContact CB-CG1 3.82Å; F165-V169 PolarHBondContact O-N 3.28Å; L166-V169 HydrophobicContact CD2-CG2 4.37Å; V169-R171 PolarHBondContact O-N 2.94Å; V169-L172 HydrophobicContact CB-CD1 4.44Å; V169-L172 HydrophobicContact CG1-CD1 4.46Å; V169-L172 PolarHBondContact O-N 3.43Å; V169-W200 HydrophobicContact CG1-CH2 4.42Å; V169-W200 HydrophobicContact CG1-CZ3 3.93Å; V169-A203 HydrophobicContact CG1-CB 4.37Å
170	S	92.4	Very high	92.4	Very high	4 Å²	4	32.6 Å²	32.6	3%	0.028	18%	0.182	C	C	.	.	T	Hydrogen-bonded Turn	trans	-68.7	-20.7	176.6	-57.2	0	0	0	0	113.2	R107 L166 I168	R107-S170 PolarHBondContact NE-O 3.34Å; L166-S170 WeakPolarHBondContact O-CB 3.45Å; L166-S170 PolarHBondContact O-N 3.06Å; L166-S170 VanDerWaalsContact O-N 3.09Å; L166-S170 PolarHBondContact O-OG 3.1Å; I168-S170 VanDerWaalsContact C-N 3.27Å; I168-S170 PolarHBondContact O-N 3.21Å
171	R	92.3	Very high	93.1	Very high	98 Å²	98	29.6 Å²	29.6	37%	0.37	16%	0.163	S	C	.	.	T	Hydrogen-bonded Turn	trans	-84.1	-19.4	178.1	-64.6	171.7	172.3	-89.5	-1.1	113.4	S111 Q113 M121 S167 I168 V169 N173	S111-R171 PolarHBondContact O-NH1 2.86Å; S111-R171 PolarHBondContact O-NH2 3.47Å; S111-R171 VanDerWaalsContact O-NH2 3.08Å; Q113-R171 PolarHBondContact O-NH2 3.4Å; M121-R171 HydrophobicContact CE-CB 4.33Å; M121-R171 HydrophobicContact SD-CB 4.32Å; S167-R171 WeakPolarHBondContact O-CD 3.36Å; S167-R171 VanDerWaalsContact O-CG 3.32Å; S167-R171 WeakPolarHBondContact O-CG 3.35Å; S167-R171 PolarHBondContact O-NE 3.02Å; I168-R171 WeakPolarHBondContact O-CB 3.48Å; I168-R171 PolarHBondContact O-N 3.44Å; V169-R171 PolarHBondContact O-N 2.94Å; R171-N173 PolarHBondContact O-N 3.1Å
172	L	92.9	Very high	93.5	Very high	4 Å²	4	33.2 Å²	33.2	2%	0.021	18%	0.178	C	C	.	.			trans	-69.5	131.1	-178.8	-56.5	176.9	0	0	0	109.6	R107 M121 W130 V169 T176 V177 L204	R107-L172 PolarHBondContact NH2-O 3.5Å; M121-L172 HydrophobicContact CE-CD2 3.34Å; M121-L172 HydrophobicContact CE-CG 4.35Å; W130-L172 HydrophobicContact CH2-CD2 3.63Å; W130-L172 HydrophobicContact CZ2-CD2 4.33Å; W130-L172 HydrophobicContact CZ3-CD2 4.39Å; V169-L172 HydrophobicContact CB-CD1 4.44Å; V169-L172 HydrophobicContact CG1-CD1 4.46Å; V169-L172 PolarHBondContact O-N 3.43Å; L172-T176 HydrophobicContact CD2-CG2 3.85Å; L172-V177 HydrophobicContact CB-CG2 3.69Å; L172-V177 HydrophobicContact CD1-CG2 4.32Å; L172-L204 HydrophobicContact CD1-CD2 4.09Å
173	N	93.1	Very high	93.8	Very high	86 Å²	86	33.9 Å²	33.9	46%	0.46	18%	0.18	S	C	.	.			trans	-76.8	167.7	169	69.7	19.4	0	0	0	110.4	R171 A175 T176 V177	R171-N173 PolarHBondContact O-N 3.1Å; N173-A175 VanDerWaalsContact C-N 3.31Å; N173-A175 PolarHBondContact O-N 3.46Å; N173-A175 PolarHBondContact OD1-N 2.99Å; N173-T176 PolarHBondContact O-N 3.09Å; N173-T176 VanDerWaalsContact OD1-CB 3.22Å; N173-T176 WeakPolarHBondContact OD1-CB 3.43Å; N173-T176 PolarHBondContact OD1-N 3Å; N173-T176 PolarHBondContact OD1-OG1 2.88Å; N173-V177 WeakPolarHBondContact O-CG2 3.46Å; N173-V177 PolarHBondContact O-N 3.03Å
174	Q	93.2	Very high	93.9	Very high	51 Å²	51	32.3 Å²	32.3	24%	0.238	17%	0.17	C	C	.	.	H	α-helix	trans	-62	-36.6	-177.1	-69.4	-57.1	-43.3	0	0	113.1	T176 V177 S178 C207 E209	Q174-T176 PolarHBondContact O-N 3.27Å; Q174-V177 PolarHBondContact O-N 3.41Å; Q174-S178 PolarHBondContact O-N 3.07Å; Q174-S178 PolarHBondContact O-OG 2.83Å; Q174-C207 PolarHBondContact NE2-O 3.29Å; Q174-E209 HydrophobicContact CG-CB 4.36Å; Q174-E209 HydrophobicContact CG-CG 4.48Å; Q174-E209 VanDerWaalsContact NE2-CG 3.27Å; Q174-E209 PolarHBondContact NE2-OE1 3.31Å
175	A	93.6	Very high	93.9	Very high	51 Å²	51	31 Å²	31	42%	0.421	16%	0.162	S	C	.	.	H	α-helix	trans	-62.5	-41.7	176.5	0	0	0	0	0	112.4	N173 S178 A179	N173-A175 VanDerWaalsContact C-N 3.31Å; N173-A175 PolarHBondContact O-N 3.46Å; N173-A175 PolarHBondContact OD1-N 2.99Å; A175-S178 PolarHBondContact O-N 2.97Å; A175-A179 WeakPolarHBondContact O-CB 3.41Å; A175-A179 PolarHBondContact O-N 2.91Å
176	T	95.1	Very high	94	Very high	14 Å²	14	29.2 Å²	29.2	9%	0.086	16%	0.156	C	C	.	.	H	α-helix	trans	-70.5	-39.6	176.8	-54.5	0	0	0	0	110.8	Q124 W130 L172 N173 Q174 S178 A179 V180	Q124-T176 PolarHBondContact OE1-OG1 3Å; W130-T176 HydrophobicContact CH2-CG2 4.31Å; W130-T176 HydrophobicContact CZ2-CG2 3.73Å; L172-T176 HydrophobicContact CD2-CG2 3.85Å; N173-T176 PolarHBondContact O-N 3.09Å; N173-T176 VanDerWaalsContact OD1-CB 3.22Å; N173-T176 WeakPolarHBondContact OD1-CB 3.43Å; N173-T176 PolarHBondContact OD1-N 3Å; N173-T176 PolarHBondContact OD1-OG1 2.88Å; Q174-T176 PolarHBondContact O-N 3.27Å; T176-S178 VanDerWaalsContact C-N 3.32Å; T176-S178 PolarHBondContact O-N 3.36Å; T176-A179 PolarHBondContact O-N 3.43Å; T176-V180 HydrophobicContact CG2-CG2 3.93Å; T176-V180 WeakPolarHBondContact O-CB 3.44Å; T176-V180 WeakPolarHBondContact O-CG2 3.3Å; T176-V180 PolarHBondContact O-N 2.97Å
177	V	95.4	Very high	94	Very high	0 Å²	0	26.8 Å²	26.8	0%	0	14%	0.143	C	C	.	.	H	α-helix	trans	-58.6	-46.4	174.3	171.4	0	0	0	0	110.5	L172 N173 Q174 L181 L204 C207 L208	L172-V177 HydrophobicContact CB-CG2 3.69Å; L172-V177 HydrophobicContact CD1-CG2 4.32Å; N173-V177 WeakPolarHBondContact O-CG2 3.46Å; N173-V177 PolarHBondContact O-N 3.03Å; Q174-V177 PolarHBondContact O-N 3.41Å; V177-L181 VanDerWaalsContact O-CB 3.22Å; V177-L181 WeakPolarHBondContact O-CB 3.09Å; V177-L181 PolarHBondContact O-N 3.1Å; V177-L204 HydrophobicContact CG1-CB 4.4Å; V177-L204 HydrophobicContact CG1-CD2 4.15Å; V177-C207 HydrophobicContact CG1-CB 4.31Å; V177-C207 HydrophobicContact CG2-CB 4.1Å; V177-L208 HydrophobicContact CG1-CB 4.25Å
178	S	94.4	Very high	94.2	Very high	34 Å²	34	25.6 Å²	25.6	24%	0.238	13%	0.134	C	C	.	.	H	α-helix	trans	-64	-47	176.8	-66.5	0	0	0	0	112.6	Q174 A175 T176 L181 E182	Q174-S178 PolarHBondContact O-N 3.07Å; Q174-S178 PolarHBondContact O-OG 2.83Å; A175-S178 PolarHBondContact O-N 2.97Å; T176-S178 VanDerWaalsContact C-N 3.32Å; T176-S178 PolarHBondContact O-N 3.36Å; S178-L181 PolarHBondContact O-N 3Å; S178-E182 PolarHBondContact O-N 3.27Å
179	A	95.3	Very high	94.1	Very high	11 Å²	11	30 Å²	30	9%	0.091	16%	0.155	C	C	.	.	H	α-helix	trans	-63	-45.8	179.8	0	0	0	0	0	112.2	Q124 A175 T176 L181 E182 Y183	Q124-A179 HydrophobicContact CG-CB 4.25Å; A175-A179 WeakPolarHBondContact O-CB 3.41Å; A175-A179 PolarHBondContact O-N 2.91Å; T176-A179 PolarHBondContact O-N 3.43Å; A179-L181 VanDerWaalsContact C-N 3.33Å; A179-L181 PolarHBondContact O-N 3.28Å; A179-E182 WeakPolarHBondContact O-CB 3.41Å; A179-E182 PolarHBondContact O-N 3.48Å; A179-Y183 HydrophobicContact CB-CE2 4.1Å; A179-Y183 WeakPolarHBondContact O-CD1 3.37Å; A179-Y183 VanDerWaalsContact O-CD2 3.24Å; A179-Y183 WeakPolarHBondContact O-CD2 3.4Å; A179-Y183 PolarHBondContact O-N 3.39Å
180	V	96.1	Very high	93.5	Very high	1 Å²	1	38.2 Å²	38.2	1%	0.006	19%	0.193	C	C	.	.	H	α-helix	trans	-66.4	-38.2	178.3	179.6	0	0	0	0	110.8	W130 T176 E182 Y183 L184 L204	W130-V180 HydrophobicContact CB-CG2 4.45Å; W130-V180 HydrophobicContact CD2-CG1 4.43Å; W130-V180 HydrophobicContact CD2-CG2 3.41Å; W130-V180 VanDerWaalsContact CD2-CG2 3.41Å; W130-V180 HydrophobicContact CE3-CG1 4.13Å; W130-V180 HydrophobicContact CE3-CG2 3.71Å; W130-V180 HydrophobicContact CG-CG2 3.76Å; W130-V180 HydrophobicContact CH2-CG2 4.36Å; W130-V180 HydrophobicContact CZ2-CG2 4.1Å; W130-V180 HydrophobicContact CZ3-CG2 4.17Å; T176-V180 HydrophobicContact CG2-CG2 3.93Å; T176-V180 WeakPolarHBondContact O-CB 3.44Å; T176-V180 WeakPolarHBondContact O-CG2 3.3Å; T176-V180 PolarHBondContact O-N 2.97Å; V180-E182 VanDerWaalsContact C-N 3.33Å; V180-E182 PolarHBondContact O-N 3.18Å; V180-Y183 PolarHBondContact O-N 3.47Å; V180-L184 HydrophobicContact CG1-CD1 4.21Å; V180-L184 HydrophobicContact CG1-CG 4.37Å; V180-L184 VanDerWaalsContact O-CG 3.3Å; V180-L184 WeakPolarHBondContact O-CG 3.44Å; V180-L184 PolarHBondContact O-N 3.39Å; V180-L204 HydrophobicContact CB-CD1 4.33Å; V180-L204 HydrophobicContact CB-CD2 4.44Å; V180-L204 HydrophobicContact CG1-CD1 3.83Å; V180-L204 HydrophobicContact CG1-CD2 4.39Å
181	L	96.1	Very high	93.3	Very high	1 Å²	1	42.2 Å²	42.2	1%	0.005	21%	0.208	C	C	.	.	H	α-helix	trans	-60.7	-44.3	174.3	-176.8	63.1	0	0	0	111	V177 S178 A179 L184 I185 L204 L205 L208 I220	V177-L181 VanDerWaalsContact O-CB 3.22Å; V177-L181 WeakPolarHBondContact O-CB 3.09Å; V177-L181 PolarHBondContact O-N 3.1Å; S178-L181 PolarHBondContact O-N 3Å; A179-L181 VanDerWaalsContact C-N 3.33Å; A179-L181 PolarHBondContact O-N 3.28Å; L181-L184 PolarHBondContact O-N 3.23Å; L181-I185 HydrophobicContact CD1-CD1 4.05Å; L181-I185 HydrophobicContact CD1-CG1 4.4Å; L181-I185 HydrophobicContact CD2-CD1 4.5Å; L181-I185 HydrophobicContact CG-CD1 3.78Å; L181-I185 WeakPolarHBondContact O-CB 3.19Å; L181-I185 WeakPolarHBondContact O-CD1 3.03Å; L181-I185 WeakPolarHBondContact O-CG1 3.49Å; L181-I185 PolarHBondContact O-N 2.71Å; L181-L204 HydrophobicContact CB-CB 4.47Å; L181-L204 HydrophobicContact CB-CD1 4.25Å; L181-L204 HydrophobicContact CD1-CB 4.18Å; L181-L204 HydrophobicContact CD1-CD1 4.34Å; L181-L205 HydrophobicContact CD2-CD2 4.27Å; L181-L208 HydrophobicContact CD2-CD1 3.71Å; L181-I220 HydrophobicContact CD2-CG2 4.04Å
182	E	95.9	Very high	93.1	Very high	82 Å²	82	44.5 Å²	44.5	38%	0.383	22%	0.222	S	C	.	.	H	α-helix	trans	-59.4	-49.7	174.2	-179.9	175.4	-178.7	0	0	111.8	S178 A179 V180 L184 I185 N186 L219	S178-E182 PolarHBondContact O-N 3.27Å; A179-E182 WeakPolarHBondContact O-CB 3.41Å; A179-E182 PolarHBondContact O-N 3.48Å; V180-E182 VanDerWaalsContact C-N 3.33Å; V180-E182 PolarHBondContact O-N 3.18Å; E182-L184 VanDerWaalsContact C-N 3.27Å; E182-L184 PolarHBondContact O-N 2.73Å; E182-I185 PolarHBondContact O-N 3.08Å; E182-I185 VanDerWaalsContact O-N 3.11Å; E182-N186 WeakPolarHBondContact O-CB 3.42Å; E182-N186 PolarHBondContact O-N 3.31Å; E182-N186 PolarHBondContact O-OD1 2.9Å; E182-L219 HydrophobicContact CB-CD1 4Å; E182-L219 HydrophobicContact CB-CD2 4Å; E182-L219 HydrophobicContact CG-CD2 3.81Å
183	Y	95.4	Very high	93	Very high	28 Å²	28	44.7 Å²	44.7	11%	0.11	22%	0.223	C	C	.	.	H	α-helix	trans	-58.1	-39.1	179.1	-58.2	-28	0	0	0	113	Q124 E127 W130 K131 A179 V180 W187	Q124-Y183 WeakPolarHBondContact O-CE2 3.47Å; Q124-Y183 PolarHBondContact O-OH 2.97Å; E127-Y183 HydrophobicContact CB-CD1 3.84Å; E127-Y183 HydrophobicContact CB-CD2 4.18Å; E127-Y183 HydrophobicContact CB-CE1 3.79Å; E127-Y183 HydrophobicContact CB-CE2 4.13Å; E127-Y183 HydrophobicContact CB-CG 4.05Å; E127-Y183 HydrophobicContact CG-CD1 3.5Å; E127-Y183 HydrophobicContact CG-CD2 4.27Å; E127-Y183 HydrophobicContact CG-CE1 3.96Å; E127-Y183 HydrophobicContact CG-CG 3.69Å; W130-Y183 HydrophobicContact CB-CD2 4.06Å; W130-Y183 AromaticContact CD1-CE2 3.98Å; W130-Y183 HydrophobicContact CG-CD2 4.32Å; K131-Y183 WeakPolarHBondContact CE-O 3.39Å; A179-Y183 HydrophobicContact CB-CE2 4.1Å; A179-Y183 WeakPolarHBondContact O-CD1 3.37Å; A179-Y183 VanDerWaalsContact O-CD2 3.24Å; A179-Y183 WeakPolarHBondContact O-CD2 3.4Å; A179-Y183 PolarHBondContact O-N 3.39Å; V180-Y183 PolarHBondContact O-N 3.47Å; Y183-W187 WeakPolarHBondContact O-CB 3.33Å; Y183-W187 PolarHBondContact O-N 2.8Å
184	L	95	Very high	93	Very high	1 Å²	1	42 Å²	42	1%	0.005	21%	0.209	C	C	.	.	H	α-helix	trans	-75.2	-33.3	178.1	-67.4	-177	0	0	0	112.7	C134 L135 V180 L181 E182 F188 L197 W200 L204	C134-L184 HydrophobicContact CB-CD1 4.48Å; C134-L184 HydrophobicContact CB-CD2 4.03Å; L135-L184 HydrophobicContact CD1-CD2 4.37Å; L135-L184 HydrophobicContact CG-CD2 4.32Å; V180-L184 HydrophobicContact CG1-CD1 4.21Å; V180-L184 HydrophobicContact CG1-CG 4.37Å; V180-L184 VanDerWaalsContact O-CG 3.3Å; V180-L184 WeakPolarHBondContact O-CG 3.44Å; V180-L184 PolarHBondContact O-N 3.39Å; L181-L184 PolarHBondContact O-N 3.23Å; E182-L184 VanDerWaalsContact C-N 3.27Å; E182-L184 PolarHBondContact O-N 2.73Å; L184-F188 WeakPolarHBondContact O-CB 3.46Å; L184-F188 PolarHBondContact O-N 2.96Å; L184-F188 VanDerWaalsContact O-N 3.1Å; L184-L197 HydrophobicContact CB-CD1 3.85Å; L184-L197 HydrophobicContact CD2-CD1 4.14Å; L184-L197 HydrophobicContact CG-CD1 4.4Å; L184-W200 HydrophobicContact CD1-CB 3.64Å; L184-W200 HydrophobicContact CD1-CG 4.32Å; L184-L204 HydrophobicContact CD1-CD1 3.71Å
185	I	94.7	Very high	92.8	Very high	0 Å²	0	42.8 Å²	42.8	0%	0	22%	0.219	C	C	.	.	H	α-helix	trans	-67.5	-48	173.2	-69.6	166.6	0	0	0	109.7	L181 E182 W187 F188 E189 L219 Q222 L223	L181-I185 HydrophobicContact CD1-CD1 4.05Å; L181-I185 HydrophobicContact CD1-CG1 4.4Å; L181-I185 HydrophobicContact CD2-CD1 4.5Å; L181-I185 HydrophobicContact CG-CD1 3.78Å; L181-I185 WeakPolarHBondContact O-CB 3.19Å; L181-I185 WeakPolarHBondContact O-CD1 3.03Å; L181-I185 WeakPolarHBondContact O-CG1 3.49Å; L181-I185 PolarHBondContact O-N 2.71Å; E182-I185 PolarHBondContact O-N 3.08Å; E182-I185 VanDerWaalsContact O-N 3.11Å; I185-W187 VanDerWaalsContact C-N 3.29Å; I185-W187 PolarHBondContact O-N 3.09Å; I185-F188 CarbonylContact O-C 3.55Å; I185-F188 WeakPolarHBondContact O-CA 3.41Å; I185-F188 WeakPolarHBondContact O-CB 3.47Å; I185-F188 PolarHBondContact O-N 3.33Å; I185-E189 PolarHBondContact O-N 2.97Å; I185-L219 HydrophobicContact CD1-CB 4.18Å; I185-Q222 HydrophobicContact CG2-CB 4.39Å; I185-L223 HydrophobicContact CD1-CB 3.88Å; I185-L223 HydrophobicContact CG1-CB 4Å; I185-L223 HydrophobicContact CG1-CD1 4.27Å; I185-L223 HydrophobicContact CG1-CG 4.5Å
186	N	93.8	Very high	92.7	Very high	52 Å²	52	43.1 Å²	43.1	28%	0.278	21%	0.212	S	C	.	.	H	α-helix	trans	-59	-41.6	177.5	-66	-8.5	0	0	0	111.2	E182 F188 E189	E182-N186 WeakPolarHBondContact O-CB 3.42Å; E182-N186 PolarHBondContact O-N 3.31Å; E182-N186 PolarHBondContact O-OD1 2.9Å; N186-F188 VanDerWaalsContact C-N 3.29Å; N186-F188 PolarHBondContact O-N 2.65Å; N186-E189 PolarHBondContact O-N 2.94Å
187	W	92.8	Very high	92.7	Very high	17 Å²	17	42.4 Å²	42.4	6%	0.064	21%	0.208	C	C	.	.	H	α-helix	trans	-62	-37.3	173.8	-173.5	88.5	0	0	0	112.4	K131 L135 V139 Y183 I185 E189 R191 V194 L197	K131-W187 HydrophobicContact CD-CB 4.37Å; K131-W187 HydrophobicContact CD-CG 4.5Å; L135-W187 HydrophobicContact CD1-CD2 3.49Å; L135-W187 VanDerWaalsContact CD1-CD2 3.49Å; L135-W187 HydrophobicContact CD1-CE3 3.69Å; L135-W187 HydrophobicContact CD1-CG 4.08Å; L135-W187 HydrophobicContact CD1-CH2 3.99Å; L135-W187 HydrophobicContact CD1-CZ2 3.8Å; L135-W187 HydrophobicContact CD1-CZ3 3.94Å; V139-W187 HydrophobicContact CG1-CH2 3.76Å; V139-W187 HydrophobicContact CG1-CZ2 3.89Å; Y183-W187 WeakPolarHBondContact O-CB 3.33Å; Y183-W187 PolarHBondContact O-N 2.8Å; I185-W187 VanDerWaalsContact C-N 3.29Å; I185-W187 PolarHBondContact O-N 3.09Å; W187-E189 VanDerWaalsContact C-N 3.33Å; W187-E189 PolarHBondContact O-N 3.03Å; W187-R191 HydrophobicContact CD2-CB 4.1Å; W187-R191 HydrophobicContact CD2-CG 3.98Å; W187-R191 HydrophobicContact CE3-CB 3.95Å; W187-R191 HydrophobicContact CE3-CG 4.36Å; W187-R191 HydrophobicContact CG-CG 4.46Å; W187-R191 HydrophobicContact CH2-CB 3.74Å; W187-R191 HydrophobicContact CH2-CG 4.23Å; W187-R191 HydrophobicContact CZ2-CB 3.9Å; W187-R191 HydrophobicContact CZ2-CG 3.85Å; W187-R191 HydrophobicContact CZ3-CB 3.77Å; W187-R191 HydrophobicContact CZ3-CG 4.47Å; W187-R191 VanDerWaalsContact O-CB 3.27Å; W187-R191 WeakPolarHBondContact O-CB 3.36Å; W187-R191 VanDerWaalsContact O-CG 3.23Å; W187-R191 WeakPolarHBondContact O-CG 3.12Å; W187-R191 PolarHBondContact O-N 2.86Å; W187-V194 HydrophobicContact CH2-CG2 4.28Å; W187-V194 HydrophobicContact CZ3-CG2 4.25Å; W187-L197 HydrophobicContact CE3-CD1 4.27Å; W187-L197 HydrophobicContact CE3-CD2 4.21Å; W187-L197 HydrophobicContact CZ3-CD2 4.08Å
188	F	94.1	Very high	92.6	Very high	0 Å²	0	42.8 Å²	42.8	0%	0	21%	0.211	C	C	.	.	H	α-helix	trans	-74.4	-17.7	179.7	-177.8	-134.9	0	0	0	114.2	L184 I185 N186 E190 F193 L197 L223 R226 V230 L245	L184-F188 WeakPolarHBondContact O-CB 3.46Å; L184-F188 PolarHBondContact O-N 2.96Å; L184-F188 VanDerWaalsContact O-N 3.1Å; I185-F188 CarbonylContact O-C 3.55Å; I185-F188 WeakPolarHBondContact O-CA 3.41Å; I185-F188 WeakPolarHBondContact O-CB 3.47Å; I185-F188 PolarHBondContact O-N 3.33Å; N186-F188 VanDerWaalsContact C-N 3.29Å; N186-F188 PolarHBondContact O-N 2.65Å; F188-E190 VanDerWaalsContact C-N 3.32Å; F188-E190 PolarHBondContact O-N 3.32Å; F188-F193 HydrophobicContact CD2-CD2 4.44Å; F188-F193 HydrophobicContact CE1-CD2 4.48Å; F188-F193 HydrophobicContact CE2-CB 3.66Å; F188-F193 AromaticContact CE2-CD2 3.78Å; F188-F193 HydrophobicContact CE2-CD2 3.78Å; F188-F193 HydrophobicContact CE2-CG 4.23Å; F188-F193 HydrophobicContact CZ-CB 4.21Å; F188-F193 AromaticContact CZ-CD2 3.79Å; F188-F193 HydrophobicContact CZ-CD2 3.79Å; F188-F193 HydrophobicContact CZ-CG 4.47Å; F188-L197 HydrophobicContact CB-CD2 3.75Å; F188-L197 HydrophobicContact CD2-CD2 3.62Å; F188-L197 HydrophobicContact CE2-CD2 4.41Å; F188-L197 HydrophobicContact CG-CD2 3.69Å; F188-L223 HydrophobicContact CD1-CD1 3.95Å; F188-L223 HydrophobicContact CE1-CD1 4.15Å; F188-R226 HydrophobicContact CD1-CB 4.09Å; F188-R226 HydrophobicContact CD1-CG 3.53Å; F188-R226 HydrophobicContact CE1-CB 3.87Å; F188-R226 HydrophobicContact CE1-CG 3.4Å; F188-R226 VanDerWaalsContact CE1-CG 3.4Å; F188-R226 HydrophobicContact CE2-CG 4.43Å; F188-R226 HydrophobicContact CG-CG 4.14Å; F188-R226 HydrophobicContact CZ-CG 3.88Å; F188-R226 PolarHBondContact O-NE 3.18Å; F188-R226 VanDerWaalsContact O-NE 3.08Å; F188-V230 HydrophobicContact CE2-CG2 3.99Å; F188-V230 HydrophobicContact CZ-CB 4.41Å; F188-V230 HydrophobicContact CZ-CG2 3.79Å; F188-L245 HydrophobicContact CZ-CD2 4.17Å
189	E	89.7	Confident	92.7	Very high	94 Å²	94	48.5 Å²	48.5	44%	0.439	23%	0.228	S	C	.	.	H	α-helix	trans	-62.3	-41.4	176	-68.5	-168.2	155.8	0	0	111.6	I185 N186 W187 R226	I185-E189 PolarHBondContact O-N 2.97Å; N186-E189 PolarHBondContact O-N 2.94Å; W187-E189 VanDerWaalsContact C-N 3.33Å; W187-E189 PolarHBondContact O-N 3.03Å; E189-R226 PolarHBondContact O-NE 2.91Å; E189-R226 VanDerWaalsContact O-NE 3.14Å; E189-R226 PolarHBondContact O-NH2 3.45Å
190	E	83.3	Confident	92.7	Very high	173 Å²	173	48.1 Å²	48.1	81%	0.808	22%	0.224	S	C	*	.	H	α-helix	trans	-102.8	-9.7	-174.6	-60.6	-174.9	167.4	0	0	114.2	F188	F188-E190 VanDerWaalsContact C-N 3.32Å; F188-E190 PolarHBondContact O-N 3.32Å
191	R	87.8	Confident	92.7	Very high	89 Å²	89	48 Å²	48	34%	0.336	22%	0.223	S	C	.	.	S	Bend	trans	-117.6	166.7	-171.7	-59	-73.5	-177.2	141.3	-1.6	112.3	N142 W187	N142-R191 PolarHBondContact ND2-NH1 2.99Å; N142-R191 PolarHBondContact OD1-NH1 3.31Å; N142-R191 VanDerWaalsContact OD1-NH1 3.1Å; W187-R191 HydrophobicContact CD2-CB 4.1Å; W187-R191 HydrophobicContact CD2-CG 3.98Å; W187-R191 HydrophobicContact CE3-CB 3.95Å; W187-R191 HydrophobicContact CE3-CG 4.36Å; W187-R191 HydrophobicContact CG-CG 4.46Å; W187-R191 HydrophobicContact CH2-CB 3.74Å; W187-R191 HydrophobicContact CH2-CG 4.23Å; W187-R191 HydrophobicContact CZ2-CB 3.9Å; W187-R191 HydrophobicContact CZ2-CG 3.85Å; W187-R191 HydrophobicContact CZ3-CB 3.77Å; W187-R191 HydrophobicContact CZ3-CG 4.47Å; W187-R191 VanDerWaalsContact O-CB 3.27Å; W187-R191 WeakPolarHBondContact O-CB 3.36Å; W187-R191 VanDerWaalsContact O-CG 3.23Å; W187-R191 WeakPolarHBondContact O-CG 3.12Å; W187-R191 PolarHBondContact O-N 2.86Å
192	E	88.6	Confident	92.8	Very high	145 Å²	145	50.5 Å²	50.5	68%	0.678	23%	0.233	S	C	*	.			trans	-73.7	154.2	175.9	-64.1	-171.8	176.2	0	0	112.1	V194	E192-V194 PolarHBondContact O-N 3.46Å
193	F	90.8	Very high	92.8	Very high	9 Å²	9	47.2 Å²	47.2	4%	0.039	22%	0.22	C	C	.	.			trans	-72.1	121.7	174.2	-174.2	-95.1	0	0	0	110.5	F188 L197 V230 R241 P244 L245	F188-F193 HydrophobicContact CD2-CD2 4.44Å; F188-F193 HydrophobicContact CE1-CD2 4.48Å; F188-F193 HydrophobicContact CE2-CB 3.66Å; F188-F193 AromaticContact CE2-CD2 3.78Å; F188-F193 HydrophobicContact CE2-CD2 3.78Å; F188-F193 HydrophobicContact CE2-CG 4.23Å; F188-F193 HydrophobicContact CZ-CB 4.21Å; F188-F193 AromaticContact CZ-CD2 3.79Å; F188-F193 HydrophobicContact CZ-CD2 3.79Å; F188-F193 HydrophobicContact CZ-CG 4.47Å; F193-L197 HydrophobicContact CD2-CD2 4.23Å; F193-V230 HydrophobicContact CB-CG1 4.39Å; F193-R241 HydrophobicContact CD1-CB 4.09Å; F193-R241 HydrophobicContact CD1-CG 4.02Å; F193-P244 HydrophobicContact CE1-CB 3.62Å; F193-P244 HydrophobicContact CE1-CG 4.12Å; F193-P244 HydrophobicContact CZ-CB 3.53Å; F193-P244 HydrophobicContact CZ-CG 4.46Å; F193-L245 HydrophobicContact CD2-CD2 3.86Å; F193-L245 HydrophobicContact CE2-CD2 4.2Å; F193-L245 HydrophobicContact CG-CD2 4.1Å
194	V	91.3	Very high	92.9	Very high	28 Å²	28	45.9 Å²	45.9	17%	0.17	22%	0.215	C	C	.	.			trans	-112.8	148.4	173.8	-63.4	0	0	0	0	111.6	L135 V139 W187 E192 Q196 L197 G198	L135-V194 HydrophobicContact CD2-CG2 4.28Å; V139-V194 HydrophobicContact CG1-CG1 4.1Å; V139-V194 HydrophobicContact CG1-CG2 4.1Å; W187-V194 HydrophobicContact CH2-CG2 4.28Å; W187-V194 HydrophobicContact CZ3-CG2 4.25Å; E192-V194 PolarHBondContact O-N 3.46Å; V194-Q196 VanDerWaalsContact C-N 3.27Å; V194-Q196 HydrophobicContact CG2-CB 4.49Å; V194-Q196 PolarHBondContact O-N 2.96Å; V194-L197 HydrophobicContact CG2-CB 3.51Å; V194-L197 WeakPolarHBondContact O-CB 3.46Å; V194-L197 PolarHBondContact O-N 3.27Å; V194-L197 VanDerWaalsContact O-N 3.16Å; V194-G198 PolarHBondContact O-N 3.35Å; V194-G198 VanDerWaalsContact O-N 3.15Å
195	P	90.2	Very high	93	Very high	68 Å²	68	45.8 Å²	45.8	44%	0.442	21%	0.214	S	C	.	.	H	α-helix	trans	-58.6	-34.4	179.5	-26.7	35.5	0	0	0	114.3	L197 G198 R199	P195-L197 VanDerWaalsContact C-N 3.34Å; P195-G198 PolarHBondContact O-N 3.34Å; P195-R199 WeakPolarHBondContact O-CG 3.46Å; P195-R199 PolarHBondContact O-N 2.95Å
196	Q	91.4	Very high	93	Very high	58 Å²	58	46 Å²	46	27%	0.271	22%	0.216	S	C	.	.	H	α-helix	trans	-60.4	-45.5	177.1	-64.8	83.5	-15.6	0	0	111	L135 V194 R199 W200	L135-Q196 HydrophobicContact CD2-CB 4.35Å; V194-Q196 VanDerWaalsContact C-N 3.27Å; V194-Q196 HydrophobicContact CG2-CB 4.49Å; V194-Q196 PolarHBondContact O-N 2.96Å; Q196-R199 PolarHBondContact O-N 3.48Å; Q196-W200 PolarHBondContact O-N 2.9Å; Q196-W200 VanDerWaalsContact O-N 3.08Å
197	L	93.7	Very high	93.1	Very high	0 Å²	0	43.7 Å²	43.7	0%	0	20%	0.204	C	C	.	.	H	α-helix	trans	-59.7	-48.1	175.7	176.8	73.9	0	0	0	110.3	L135 L184 W187 F188 F193 V194 P195 R199 W200 Q201	L135-L197 HydrophobicContact CD2-CB 3.85Å; L135-L197 HydrophobicContact CD2-CD1 4.19Å; L184-L197 HydrophobicContact CB-CD1 3.85Å; L184-L197 HydrophobicContact CD2-CD1 4.14Å; L184-L197 HydrophobicContact CG-CD1 4.4Å; W187-L197 HydrophobicContact CE3-CD1 4.27Å; W187-L197 HydrophobicContact CE3-CD2 4.21Å; W187-L197 HydrophobicContact CZ3-CD2 4.08Å; F188-L197 HydrophobicContact CB-CD2 3.75Å; F188-L197 HydrophobicContact CD2-CD2 3.62Å; F188-L197 HydrophobicContact CE2-CD2 4.41Å; F188-L197 HydrophobicContact CG-CD2 3.69Å; F193-L197 HydrophobicContact CD2-CD2 4.23Å; V194-L197 HydrophobicContact CG2-CB 3.51Å; V194-L197 WeakPolarHBondContact O-CB 3.46Å; V194-L197 PolarHBondContact O-N 3.27Å; V194-L197 VanDerWaalsContact O-N 3.16Å; P195-L197 VanDerWaalsContact C-N 3.34Å; L197-R199 VanDerWaalsContact C-N 3.33Å; L197-R199 PolarHBondContact O-N 3.22Å; L197-W200 PolarHBondContact O-N 3.43Å; L197-Q201 HydrophobicContact CD1-CG 4.26Å; L197-Q201 HydrophobicContact CG-CG 4.28Å; L197-Q201 WeakPolarHBondContact O-CB 3.44Å; L197-Q201 WeakPolarHBondContact O-CG 3.25Å; L197-Q201 PolarHBondContact O-N 2.95Å
198	G	94.5	Very high	93.2	Very high	7 Å²	7	43 Å²	43	7%	0.072	20%	0.202	C	C	.	.	H	α-helix	trans	-58.6	-41.4	178.1	0	0	0	0	0	113.3	V194 P195 Y202 M248	V194-G198 PolarHBondContact O-N 3.35Å; V194-G198 VanDerWaalsContact O-N 3.15Å; P195-G198 PolarHBondContact O-N 3.34Å; G198-Y202 VanDerWaalsContact O-CB 3.3Å; G198-Y202 WeakPolarHBondContact O-CB 3.38Å; G198-Y202 PolarHBondContact O-N 3.44Å; G198-M248 WeakPolarHBondContact O-CE 3.41Å
199	R	95.4	Very high	93	Very high	155 Å²	155	47.5 Å²	47.5	59%	0.585	22%	0.222	S	C	*	.	H	α-helix	trans	-62.6	-45.3	175.6	-69.1	171.4	-171.1	171.3	3	111.5	P164 P195 Q196 L197 Y202 A203	P164-R199 HydrophobicContact CG-CB 4.11Å; P195-R199 WeakPolarHBondContact O-CG 3.46Å; P195-R199 PolarHBondContact O-N 2.95Å; Q196-R199 PolarHBondContact O-N 3.48Å; L197-R199 VanDerWaalsContact C-N 3.33Å; L197-R199 PolarHBondContact O-N 3.22Å; R199-Y202 PolarHBondContact O-N 3.46Å; R199-A203 WeakPolarHBondContact O-CB 3.39Å; R199-A203 PolarHBondContact O-N 3.38Å
200	W	96.4	Very high	92.9	Very high	2 Å²	2	47.4 Å²	47.4	1%	0.008	22%	0.221	C	C	.	.	H	α-helix	trans	-65.7	-47.5	178.2	-89	104.8	0	0	0	112.5	F133 C134 F162 P164 I168 V169 L184 Q196 L197 Y202 A203 L204	F133-W200 HydrophobicContact CD1-CH2 4.39Å; F133-W200 HydrophobicContact CD1-CZ2 4.21Å; F133-W200 AromaticContact CE1-CH2 3.94Å; F133-W200 HydrophobicContact CE1-CH2 3.94Å; F133-W200 AromaticContact CE1-CZ2 3.94Å; F133-W200 HydrophobicContact CE1-CZ2 3.94Å; C134-W200 HydrophobicContact CB-CD2 3.96Å; C134-W200 HydrophobicContact CB-CG 3.9Å; C134-W200 HydrophobicContact CB-CZ2 4.45Å; C134-W200 PolarHBondContact O-NE1 2.85Å; C134-W200 VanDerWaalsContact O-NE1 3.12Å; F162-W200 VanDerWaalsContact O-CE2 3.26Å; F162-W200 VanDerWaalsContact O-CZ2 3.28Å; F162-W200 WeakPolarHBondContact O-CZ2 3.5Å; F162-W200 PolarHBondContact O-NE1 3.33Å; P164-W200 HydrophobicContact CB-CD2 3.78Å; P164-W200 HydrophobicContact CB-CE3 3.78Å; P164-W200 HydrophobicContact CB-CG 4.39Å; P164-W200 HydrophobicContact CB-CH2 4.13Å; P164-W200 HydrophobicContact CB-CZ2 4.14Å; P164-W200 HydrophobicContact CB-CZ3 3.95Å; P164-W200 HydrophobicContact CG-CD2 4.32Å; P164-W200 HydrophobicContact CG-CG 4.45Å; I168-W200 HydrophobicContact CG2-CH2 4.13Å; V169-W200 HydrophobicContact CG1-CH2 4.42Å; V169-W200 HydrophobicContact CG1-CZ3 3.93Å; L184-W200 HydrophobicContact CD1-CB 3.64Å; L184-W200 HydrophobicContact CD1-CG 4.32Å; Q196-W200 PolarHBondContact O-N 2.9Å; Q196-W200 VanDerWaalsContact O-N 3.08Å; L197-W200 PolarHBondContact O-N 3.43Å; W200-Y202 VanDerWaalsContact C-N 3.3Å; W200-Y202 PolarHBondContact O-N 3Å; W200-A203 PolarHBondContact O-N 3.32Å; W200-L204 HydrophobicContact CE3-CD1 4.4Å; W200-L204 HydrophobicContact CE3-CG 4.3Å; W200-L204 WeakPolarHBondContact O-CB 3.4Å; W200-L204 WeakPolarHBondContact O-CG 3.34Å; W200-L204 PolarHBondContact O-N 3.01Å
201	Q	96.4	Very high	93.3	Very high	0 Å²	0	45.4 Å²	45.4	0%	0	22%	0.222	C	C	.	.	H	α-helix	trans	-56.5	-46.1	175.4	-73	172.7	-13.7	0	0	110.8	L197 A203 L204 L205 M248	L197-Q201 HydrophobicContact CD1-CG 4.26Å; L197-Q201 HydrophobicContact CG-CG 4.28Å; L197-Q201 WeakPolarHBondContact O-CB 3.44Å; L197-Q201 WeakPolarHBondContact O-CG 3.25Å; L197-Q201 PolarHBondContact O-N 2.95Å; Q201-A203 PolarHBondContact O-N 3.37Å; Q201-L204 PolarHBondContact O-N 2.83Å; Q201-L205 WeakPolarHBondContact O-CB 3.22Å; Q201-L205 WeakPolarHBondContact O-CG 3.38Å; Q201-L205 PolarHBondContact O-N 3.49Å; Q201-M248 HydrophobicContact CB-CE 3.94Å; Q201-M248 HydrophobicContact CB-SD 4.2Å
202	Y	97.3	Very high	93.4	Very high	52 Å²	52	42.3 Å²	42.3	20%	0.204	21%	0.212	C	C	.	.	H	α-helix	trans	-61.2	-46.7	177.4	-174.4	-91.5	0	0	0	112.1	F96 I99 G198 R199 W200 L205 A206 L247 L251	F96-Y202 HydrophobicContact CD2-CE1 4.27Å; F96-Y202 AromaticContact CD2-CE2 3.77Å; F96-Y202 HydrophobicContact CD2-CE2 3.77Å; F96-Y202 AromaticContact CD2-CZ 3.61Å; F96-Y202 HydrophobicContact CE2-CD2 4.43Å; F96-Y202 HydrophobicContact CE2-CE1 4.37Å; F96-Y202 HydrophobicContact CE2-CE2 4.07Å; I99-Y202 HydrophobicContact CD1-CE1 4.27Å; I99-Y202 WeakPolarHBondContact CD1-OH 3.39Å; G198-Y202 VanDerWaalsContact O-CB 3.3Å; G198-Y202 WeakPolarHBondContact O-CB 3.38Å; G198-Y202 PolarHBondContact O-N 3.44Å; R199-Y202 PolarHBondContact O-N 3.46Å; W200-Y202 VanDerWaalsContact C-N 3.3Å; W200-Y202 PolarHBondContact O-N 3Å; Y202-L205 PolarHBondContact O-N 3.47Å; Y202-A206 WeakPolarHBondContact O-CB 3.22Å; Y202-A206 PolarHBondContact O-N 2.95Å; Y202-L247 HydrophobicContact CD2-CD2 3.9Å; Y202-L247 HydrophobicContact CD2-CG 4.41Å; Y202-L247 HydrophobicContact CE2-CD1 4.48Å; Y202-L247 HydrophobicContact CE2-CD2 3.81Å; Y202-L247 HydrophobicContact CE2-CG 4.31Å; Y202-L251 HydrophobicContact CD2-CD1 3.8Å; Y202-L251 HydrophobicContact CE2-CD1 3.65Å
203	A	97.1	Very high	93.6	Very high	13 Å²	13	41 Å²	41	11%	0.107	21%	0.209	C	C	.	.	H	α-helix	trans	-65.8	-40.3	-179.3	0	0	0	0	0	112.3	P164 V169 R199 W200 Q201 A206 C207	P164-A203 HydrophobicContact CB-CB 3.45Å; P164-A203 VanDerWaalsContact CB-CB 3.45Å; P164-A203 HydrophobicContact CG-CB 3.76Å; V169-A203 HydrophobicContact CG1-CB 4.37Å; R199-A203 WeakPolarHBondContact O-CB 3.39Å; R199-A203 PolarHBondContact O-N 3.38Å; W200-A203 PolarHBondContact O-N 3.32Å; Q201-A203 PolarHBondContact O-N 3.37Å; A203-A206 WeakPolarHBondContact O-CB 3.38Å; A203-A206 PolarHBondContact O-N 3.22Å; A203-C207 PolarHBondContact O-N 2.94Å; A203-C207 PolarHBondContact O-SG 3.35Å
204	L	96.5	Very high	93.7	Very high	0 Å²	0	45 Å²	45	0%	0	24%	0.236	C	C	.	.	H	α-helix	trans	-66.4	-44.3	176	-68.8	168.4	0	0	0	111	L172 V177 V180 L181 L184 W200 Q201 A206 C207 L208	L172-L204 HydrophobicContact CD1-CD2 4.09Å; V177-L204 HydrophobicContact CG1-CB 4.4Å; V177-L204 HydrophobicContact CG1-CD2 4.15Å; V180-L204 HydrophobicContact CB-CD1 4.33Å; V180-L204 HydrophobicContact CB-CD2 4.44Å; V180-L204 HydrophobicContact CG1-CD1 3.83Å; V180-L204 HydrophobicContact CG1-CD2 4.39Å; L181-L204 HydrophobicContact CB-CB 4.47Å; L181-L204 HydrophobicContact CB-CD1 4.25Å; L181-L204 HydrophobicContact CD1-CB 4.18Å; L181-L204 HydrophobicContact CD1-CD1 4.34Å; L184-L204 HydrophobicContact CD1-CD1 3.71Å; W200-L204 HydrophobicContact CE3-CD1 4.4Å; W200-L204 HydrophobicContact CE3-CG 4.3Å; W200-L204 WeakPolarHBondContact O-CB 3.4Å; W200-L204 WeakPolarHBondContact O-CG 3.34Å; W200-L204 PolarHBondContact O-N 3.01Å; Q201-L204 PolarHBondContact O-N 2.83Å; L204-A206 PolarHBondContact O-N 3.41Å; L204-C207 PolarHBondContact O-N 3.15Å; L204-L208 WeakPolarHBondContact O-CB 3.13Å; L204-L208 PolarHBondContact O-N 2.96Å
205	L	96.6	Very high	93.8	Very high	0 Å²	0	49.5 Å²	49.5	0%	0	26%	0.256	C	S	.	.	H	α-helix	trans	-57.6	-37.6	171.3	-71.5	173.1	0	0	0	111.2	F96 R100 L181 Q201 Y202 C207 I220 L223 M248 F256	F96-L205 HydrophobicContact CE2-CB 4.49Å; F96-L205 HydrophobicContact CZ-CB 3.93Å; R100-L205 PolarHBondContact NH1-O 3.24Å; L181-L205 HydrophobicContact CD2-CD2 4.27Å; Q201-L205 WeakPolarHBondContact O-CB 3.22Å; Q201-L205 WeakPolarHBondContact O-CG 3.38Å; Q201-L205 PolarHBondContact O-N 3.49Å; Y202-L205 PolarHBondContact O-N 3.47Å; L205-C207 VanDerWaalsContact C-N 3.32Å; L205-I220 HydrophobicContact CD2-CG2 3.61Å; L205-L223 HydrophobicContact CD1-CD2 4.35Å; L205-M248 HydrophobicContact CD1-SD 3.8Å; L205-F256 HydrophobicContact CB-CE2 4.21Å; L205-F256 HydrophobicContact CB-CZ 4.27Å; L205-F256 HydrophobicContact CD2-CE2 3.83Å; L205-F256 HydrophobicContact CD2-CZ 4.13Å; L205-F256 HydrophobicContact CG-CE2 4.47Å; L205-F256 WeakPolarHBondContact O-CZ 3.09Å
206	A	96.3	Very high	93.9	Very high	3 Å²	3	46.7 Å²	46.7	3%	0.025	24%	0.238	C	C	.	.	H	α-helix	trans	-67.4	-33.7	176.4	0	0	0	0	0	112.3	F96 I99 R100 I103 Y202 A203 L204	F96-A206 HydrophobicContact CE2-CB 3.82Å; F96-A206 HydrophobicContact CZ-CB 4.19Å; I99-A206 HydrophobicContact CG2-CB 4.4Å; R100-A206 HydrophobicContact CG-CB 4.1Å; R100-A206 WeakPolarHBondContact CG-O 3.47Å; I103-A206 HydrophobicContact CD1-CB 3.65Å; Y202-A206 WeakPolarHBondContact O-CB 3.22Å; Y202-A206 PolarHBondContact O-N 2.95Å; A203-A206 WeakPolarHBondContact O-CB 3.38Å; A203-A206 PolarHBondContact O-N 3.22Å; L204-A206 PolarHBondContact O-N 3.41Å
207	C	95.3	Very high	94.1	Very high	4 Å²	4	46.2 Å²	46.2	3%	0.027	24%	0.236	C	C	.	.	H	α-helix	trans	-83.3	-14.4	179.9	-63.2	0	0	0	0	114.4	Q174 V177 A203 L204 L205 E209	Q174-C207 PolarHBondContact NE2-O 3.29Å; V177-C207 HydrophobicContact CG1-CB 4.31Å; V177-C207 HydrophobicContact CG2-CB 4.1Å; A203-C207 PolarHBondContact O-N 2.94Å; A203-C207 PolarHBondContact O-SG 3.35Å; L204-C207 PolarHBondContact O-N 3.15Å; L205-C207 VanDerWaalsContact C-N 3.32Å; C207-E209 PolarHBondContact O-N 3.41Å
208	L	94.1	Very high	94.1	Very high	4 Å²	4	48.7 Å²	48.7	2%	0.021	25%	0.253	C	S	.	.			trans	-75.5	110.8	-173.6	-168.9	141.4	0	0	0	111.9	R100 V177 L181 L204 L212 F256	R100-L208 PolarHBondContact NH1-O 3.06Å; R100-L208 PolarHBondContact NH2-O 3.11Å; V177-L208 HydrophobicContact CG1-CB 4.25Å; L181-L208 HydrophobicContact CD2-CD1 3.71Å; L204-L208 WeakPolarHBondContact O-CB 3.13Å; L204-L208 PolarHBondContact O-N 2.96Å; L208-L212 HydrophobicContact CD2-CD1 3.53Å; L208-L212 HydrophobicContact CD2-CD2 3.46Å; L208-L212 VanDerWaalsContact CD2-CD2 3.46Å; L208-L212 HydrophobicContact CD2-CG 3.35Å; L208-F256 HydrophobicContact CD2-CE1 3.93Å
209	E	90.1	Very high	94.1	Very high	93 Å²	93	49.3 Å²	49.3	44%	0.435	25%	0.254	S	S	.	.	P	Polyproline II helix	trans	-75.8	151	-171.3	-77.4	162.8	-155.8	0	0	114	R107 Q174 C207	R107-E209 IonicContact CZ-OE1 3.88Å; R107-E209 IonicContact NH1-OE1 2.95Å; R107-E209 PolarHBondContact NH1-OE1 3.49Å; Q174-E209 HydrophobicContact CG-CB 4.36Å; Q174-E209 HydrophobicContact CG-CG 4.48Å; Q174-E209 VanDerWaalsContact NE2-CG 3.27Å; Q174-E209 PolarHBondContact NE2-OE1 3.31Å; C207-E209 PolarHBondContact O-N 3.41Å
210	K	88.6	Confident	94.2	Very high	93 Å²	93	42 Å²	42	40%	0.404	23%	0.227	S	C	.	.	S	Bend	trans	-100.6	145.3	172.9	-72.9	-168.2	174.1	-161.5	0	109.4	L212 Y255 D257	K210-L212 HydrophobicContact CB-CD1 4.35Å; K210-L212 HydrophobicContact CG-CD1 3.53Å; K210-Y255 WeakPolarHBondContact CE-O 3.45Å; K210-Y255 PolarHBondContact NZ-O 2.47Å; K210-D257 IonicContact NZ-OD2 2.86Å; K210-D257 PolarHBondContact NZ-OD2 3.47Å
211	P	91	Very high	94.1	Very high	130 Å²	130	43.9 Å²	43.9	84%	0.844	23%	0.234	S	C	*	.	S	Bend	cis	-73.6	141.4	2.6	30.8	-35	0	0	0	112.7
212	L	90.7	Very high	94.1	Very high	24 Å²	24	46.6 Å²	46.6	13%	0.126	25%	0.247	C	C	.	.	P	Polyproline II helix	trans	-75.7	144.6	178.5	-89.7	73.5	0	0	0	110.5	L208 K210 A216 H217 I220 F256	L208-L212 HydrophobicContact CD2-CD1 3.53Å; L208-L212 HydrophobicContact CD2-CD2 3.46Å; L208-L212 VanDerWaalsContact CD2-CD2 3.46Å; L208-L212 HydrophobicContact CD2-CG 3.35Å; K210-L212 HydrophobicContact CB-CD1 4.35Å; K210-L212 HydrophobicContact CG-CD1 3.53Å; L212-A216 HydrophobicContact CB-CB 4.43Å; L212-A216 HydrophobicContact CD2-CB 4.2Å; L212-A216 HydrophobicContact CG-CB 4.3Å; L212-H217 WeakPolarHBondContact CB-NE2 3.17Å; L212-I220 HydrophobicContact CD2-CD1 3.82Å; L212-F256 HydrophobicContact CD1-CD1 3.8Å; L212-F256 HydrophobicContact CD1-CE1 4.03Å; L212-F256 HydrophobicContact CD2-CD1 3.77Å; L212-F256 HydrophobicContact CD2-CE1 4.28Å; L212-F256 HydrophobicContact CG-CD1 4.47Å
213	L	92.1	Very high	94	Very high	117 Å²	117	44.1 Å²	44.1	61%	0.613	24%	0.237	S	C	*	.	P	Polyproline II helix	trans	-70.4	150.9	165.6	-63.9	175	0	0	0	110.5	E215 A216 H217	L213-E215 WeakPolarHBondContact CB-OE2 3.47Å; L213-E215 PolarHBondContact O-N 3.08Å; L213-A216 WeakPolarHBondContact O-CB 3.41Å; L213-A216 PolarHBondContact O-N 3.03Å; L213-H217 PolarHBondContact O-N 3.14Å
214	P	93.7	Very high	93.9	Very high	93 Å²	93	43.5 Å²	43.5	60%	0.604	23%	0.232	S	C	*	.	H	α-helix	trans	-54.2	-35.6	176.4	-26.8	35.8	0	0	0	113.6	H217 S218	P214-H217 WeakPolarHBondContact O-CB 3.34Å; P214-H217 PolarHBondContact O-N 3.09Å; P214-S218 PolarHBondContact O-N 2.95Å
215	E	92.6	Very high	93.9	Very high	124 Å²	124	45 Å²	45	58%	0.579	24%	0.238	S	C	*	.	H	α-helix	trans	-64.3	-44.9	177.3	-61.3	73.4	-160.6	0	0	110.7	L213 H217 S218 L219	L213-E215 WeakPolarHBondContact CB-OE2 3.47Å; L213-E215 PolarHBondContact O-N 3.08Å; E215-H217 VanDerWaalsContact C-N 3.31Å; E215-H217 PolarHBondContact O-N 3.36Å; E215-S218 WeakPolarHBondContact O-CB 3.18Å; E215-S218 PolarHBondContact O-N 3.25Å; E215-S218 VanDerWaalsContact O-N 3.1Å; E215-L219 WeakPolarHBondContact O-CG 3.48Å; E215-L219 PolarHBondContact O-N 2.67Å
216	A	92.6	Very high	93.8	Very high	8 Å²	8	47.7 Å²	47.7	7%	0.066	25%	0.248	C	C	.	.	H	α-helix	trans	-62.6	-38.8	175.6	0	0	0	0	0	111.5	L212 L213 L219 I220	L212-A216 HydrophobicContact CB-CB 4.43Å; L212-A216 HydrophobicContact CD2-CB 4.2Å; L212-A216 HydrophobicContact CG-CB 4.3Å; L213-A216 WeakPolarHBondContact O-CB 3.41Å; L213-A216 PolarHBondContact O-N 3.03Å; A216-L219 PolarHBondContact O-N 2.91Å; A216-I220 WeakPolarHBondContact O-CG1 3.08Å; A216-I220 WeakPolarHBondContact O-CG2 3.48Å; A216-I220 PolarHBondContact O-N 3.31Å; A216-I220 VanDerWaalsContact O-N 3.1Å
217	H	94.7	Very high	93.7	Very high	49 Å²	49	47.6 Å²	47.6	23%	0.227	25%	0.246	C	C	.	.	H	α-helix	trans	-61.2	-44.4	171.4	-83.5	-64.4	0	0	0	112	L212 L213 P214 E215 L219 I220 R221 F256 Q258	L212-H217 WeakPolarHBondContact CB-NE2 3.17Å; L213-H217 PolarHBondContact O-N 3.14Å; P214-H217 WeakPolarHBondContact O-CB 3.34Å; P214-H217 PolarHBondContact O-N 3.09Å; E215-H217 VanDerWaalsContact C-N 3.31Å; E215-H217 PolarHBondContact O-N 3.36Å; H217-L219 PolarHBondContact O-N 3.37Å; H217-I220 VanDerWaalsContact O-CG1 3.27Å; H217-I220 WeakPolarHBondContact O-CG1 3.4Å; H217-R221 WeakPolarHBondContact O-CB 3.42Å; H217-R221 WeakPolarHBondContact O-CD 3.22Å; H217-R221 WeakPolarHBondContact O-CG 3.37Å; H217-R221 PolarHBondContact O-N 3.08Å; H217-R221 VanDerWaalsContact O-N 3.11Å; H217-F256 PolarHBondContact CE1-O 3.16Å; H217-Q258 PolarHBondContact CE1-NE2 3.42Å; H217-Q258 VanDerWaalsContact CE1-NE2 3.35Å; H217-Q258 PolarHBondContact ND1-NE2 3.13Å
218	S	94.4	Very high	93.7	Very high	52 Å²	52	47.4 Å²	47.4	36%	0.364	25%	0.245	S	C	.	.	H	α-helix	trans	-60.1	-45	177.3	-171.5	0	0	0	0	112	P214 E215 R221 Q222	P214-S218 PolarHBondContact O-N 2.95Å; E215-S218 WeakPolarHBondContact O-CB 3.18Å; E215-S218 PolarHBondContact O-N 3.25Å; E215-S218 VanDerWaalsContact O-N 3.1Å; S218-R221 WeakPolarHBondContact O-CB 3.47Å; S218-R221 PolarHBondContact O-N 3.05Å; S218-Q222 WeakPolarHBondContact O-CG 3.18Å; S218-Q222 PolarHBondContact O-N 2.92Å
219	L	94.8	Very high	93.6	Very high	20 Å²	20	50.8 Å²	50.8	11%	0.105	26%	0.261	C	S	.	.	H	α-helix	trans	-60.6	-51.9	179.1	-71.7	172	0	0	0	112	E182 I185 E215 A216 H217 R221 Q222 L223	E182-L219 HydrophobicContact CB-CD1 4Å; E182-L219 HydrophobicContact CB-CD2 4Å; E182-L219 HydrophobicContact CG-CD2 3.81Å; I185-L219 HydrophobicContact CD1-CB 4.18Å; E215-L219 WeakPolarHBondContact O-CG 3.48Å; E215-L219 PolarHBondContact O-N 2.67Å; A216-L219 PolarHBondContact O-N 2.91Å; H217-L219 PolarHBondContact O-N 3.37Å; L219-R221 PolarHBondContact O-N 3.25Å; L219-Q222 WeakPolarHBondContact O-CB 3.37Å; L219-Q222 PolarHBondContact O-N 3.5Å; L219-Q222 VanDerWaalsContact O-N 3.09Å; L219-L223 PolarHBondContact O-N 3.34Å
220	I	95.9	Very high	93.8	Very high	0 Å²	0	47 Å²	47	0%	0	25%	0.245	C	C	.	.	H	α-helix	trans	-65.2	-28.6	-179.6	66.1	176.3	0	0	0	112.2	L181 L205 L212 A216 H217 L223 A224 V252 F256	L181-I220 HydrophobicContact CD2-CG2 4.04Å; L205-I220 HydrophobicContact CD2-CG2 3.61Å; L212-I220 HydrophobicContact CD2-CD1 3.82Å; A216-I220 WeakPolarHBondContact O-CG1 3.08Å; A216-I220 WeakPolarHBondContact O-CG2 3.48Å; A216-I220 PolarHBondContact O-N 3.31Å; A216-I220 VanDerWaalsContact O-N 3.1Å; H217-I220 VanDerWaalsContact O-CG1 3.27Å; H217-I220 WeakPolarHBondContact O-CG1 3.4Å; I220-L223 WeakPolarHBondContact O-CB 3.36Å; I220-L223 PolarHBondContact O-N 2.92Å; I220-A224 PolarHBondContact O-N 2.75Å; I220-V252 HydrophobicContact CB-CG1 4.26Å; I220-V252 HydrophobicContact CB-CG2 3.98Å; I220-V252 HydrophobicContact CD1-CG1 4.28Å; I220-V252 HydrophobicContact CG1-CG1 4.04Å; I220-V252 WeakPolarHBondContact O-CG1 3.47Å; I220-V252 WeakPolarHBondContact O-CG2 3.5Å; I220-F256 HydrophobicContact CD1-CB 3.44Å; I220-F256 VanDerWaalsContact CD1-CB 3.44Å; I220-F256 HydrophobicContact CD1-CD1 4.24Å; I220-F256 HydrophobicContact CD1-CD2 4.16Å; I220-F256 HydrophobicContact CD1-CG 3.71Å
221	R	95.9	Very high	94	Very high	42 Å²	42	42.6 Å²	42.6	16%	0.158	23%	0.225	C	C	.	.	H	α-helix	trans	-69.2	-40.2	173.1	-68.7	170.3	70.9	72.7	6.2	111.6	H217 S218 L219 L223 A224 R225 Q258 D260 L261	H217-R221 WeakPolarHBondContact O-CB 3.42Å; H217-R221 WeakPolarHBondContact O-CD 3.22Å; H217-R221 WeakPolarHBondContact O-CG 3.37Å; H217-R221 PolarHBondContact O-N 3.08Å; H217-R221 VanDerWaalsContact O-N 3.11Å; S218-R221 WeakPolarHBondContact O-CB 3.47Å; S218-R221 PolarHBondContact O-N 3.05Å; L219-R221 PolarHBondContact O-N 3.25Å; R221-L223 VanDerWaalsContact C-N 3.32Å; R221-A224 PolarHBondContact O-N 3.23Å; R221-R225 WeakPolarHBondContact O-CG 3.22Å; R221-R225 PolarHBondContact O-N 3.09Å; R221-Q258 VanDerWaalsContact CD-OE1 3.24Å; R221-Q258 HydrophobicContact CG-CG 3.97Å; R221-D260 IonicContact CZ-OD1 2.72Å; R221-D260 IonicContact CZ-OD2 3.77Å; R221-D260 IonicContact NH1-OD1 3.78Å; R221-D260 PolarHBondContact NH1-OD1 3.03Å; R221-D260 IonicContact NH1-OD2 2.8Å; R221-D260 PolarHBondContact NH1-OD2 3.46Å; R221-D260 VanDerWaalsContact NH1-OD2 3.17Å; R221-D260 IonicContact NH2-OD1 3.7Å; R221-D260 IonicContact NH2-OD2 3.83Å; R221-D260 PolarHBondContact NH2-OD2 2.83Å; R221-L261 HydrophobicContact CB-CD1 3.87Å; R221-L261 HydrophobicContact CG-CD1 3.7Å
222	Q	94.8	Very high	94	Very high	58 Å²	58	38.9 Å²	38.9	27%	0.271	20%	0.2	S	C	.	.	H	α-helix	trans	-60.6	-44	172.7	-72	167.3	-12.6	0	0	110.8	I185 S218 L219 A224 R225 R226	I185-Q222 HydrophobicContact CG2-CB 4.39Å; S218-Q222 WeakPolarHBondContact O-CG 3.18Å; S218-Q222 PolarHBondContact O-N 2.92Å; L219-Q222 WeakPolarHBondContact O-CB 3.37Å; L219-Q222 PolarHBondContact O-N 3.5Å; L219-Q222 VanDerWaalsContact O-N 3.09Å; Q222-A224 PolarHBondContact O-N 3.21Å; Q222-R225 PolarHBondContact O-N 3.37Å; Q222-R226 PolarHBondContact O-N 3.08Å
223	L	95.9	Very high	94	Very high	0 Å²	0	43.8 Å²	43.8	0%	0	23%	0.227	C	C	.	.	H	α-helix	trans	-54.9	-51.1	173.2	175.8	59.8	0	0	0	111.8	I185 F188 L205 L219 I220 R221 R225 R226 S227	I185-L223 HydrophobicContact CD1-CB 3.88Å; I185-L223 HydrophobicContact CG1-CB 4Å; I185-L223 HydrophobicContact CG1-CD1 4.27Å; I185-L223 HydrophobicContact CG1-CG 4.5Å; F188-L223 HydrophobicContact CD1-CD1 3.95Å; F188-L223 HydrophobicContact CE1-CD1 4.15Å; L205-L223 HydrophobicContact CD1-CD2 4.35Å; L219-L223 PolarHBondContact O-N 3.34Å; I220-L223 WeakPolarHBondContact O-CB 3.36Å; I220-L223 PolarHBondContact O-N 2.92Å; R221-L223 VanDerWaalsContact C-N 3.32Å; L223-R225 VanDerWaalsContact C-N 3.34Å; L223-R225 PolarHBondContact O-N 3.31Å; L223-R226 PolarHBondContact O-N 2.93Å; L223-S227 WeakPolarHBondContact O-CB 3.35Å; L223-S227 PolarHBondContact O-N 2.75Å; L223-S227 PolarHBondContact O-OG 3.45Å; L223-S227 VanDerWaalsContact O-OG 3.07Å
224	A	96.3	Very high	93.9	Very high	0 Å²	0	38.8 Å²	38.8	0%	0	20%	0.201	C	C	.	.	H	α-helix	trans	-62.7	-38.3	-179.9	0	0	0	0	0	112.8	C75 I220 R221 Q222 S227 S228 I249 V252 L261	C75-A224 PolarHBondContact SG-O 2.8Å; C75-A224 VanDerWaalsContact SG-O 3.33Å; I220-A224 PolarHBondContact O-N 2.75Å; R221-A224 PolarHBondContact O-N 3.23Å; Q222-A224 PolarHBondContact O-N 3.21Å; A224-S227 PolarHBondContact O-N 2.86Å; A224-S228 WeakPolarHBondContact O-CB 3.38Å; A224-S228 PolarHBondContact O-N 3.16Å; A224-I249 HydrophobicContact CB-CG1 4.49Å; A224-V252 HydrophobicContact CB-CB 3.96Å; A224-V252 HydrophobicContact CB-CG1 3.83Å; A224-V252 HydrophobicContact CB-CG2 4.23Å; A224-L261 HydrophobicContact CB-CD1 4.16Å
225	R	94.9	Very high	93.6	Very high	32 Å²	32	42.4 Å²	42.4	12%	0.121	21%	0.209	C	C	.	.	H	α-helix	trans	-62	-50.8	173.8	-71.6	176.1	-170.7	130.1	-2.5	110.8	L72 M73 R221 Q222 L223 S227 S228 E229	L72-R225 VanDerWaalsContact CB-NH2 3.32Å; M73-R225 PolarHBondContact O-NE 2.73Å; M73-R225 PolarHBondContact O-NH2 3.12Å; R221-R225 WeakPolarHBondContact O-CG 3.22Å; R221-R225 PolarHBondContact O-N 3.09Å; Q222-R225 PolarHBondContact O-N 3.37Å; L223-R225 VanDerWaalsContact C-N 3.34Å; L223-R225 PolarHBondContact O-N 3.31Å; R225-S227 VanDerWaalsContact C-N 3.3Å; R225-S227 PolarHBondContact O-N 3.03Å; R225-S228 WeakPolarHBondContact O-CA 3.34Å; R225-S228 WeakPolarHBondContact O-CB 3.35Å; R225-S228 PolarHBondContact O-N 3.03Å; R225-S228 PolarHBondContact O-OG 3.4Å; R225-E229 WeakPolarHBondContact O-CG 3.3Å; R225-E229 PolarHBondContact O-N 2.91Å
226	R	94.6	Very high	93.4	Very high	56 Å²	56	42.5 Å²	42.5	21%	0.211	21%	0.209	C	C	.	.	H	α-helix	trans	-60.6	-41.4	179	-173.1	63.5	-172.8	147.5	-2.5	111.6	F188 E189 Q222 L223 S228 E229 V230	F188-R226 HydrophobicContact CD1-CB 4.09Å; F188-R226 HydrophobicContact CD1-CG 3.53Å; F188-R226 HydrophobicContact CE1-CB 3.87Å; F188-R226 HydrophobicContact CE1-CG 3.4Å; F188-R226 VanDerWaalsContact CE1-CG 3.4Å; F188-R226 HydrophobicContact CE2-CG 4.43Å; F188-R226 HydrophobicContact CG-CG 4.14Å; F188-R226 HydrophobicContact CZ-CG 3.88Å; F188-R226 PolarHBondContact O-NE 3.18Å; F188-R226 VanDerWaalsContact O-NE 3.08Å; E189-R226 PolarHBondContact O-NE 2.91Å; E189-R226 VanDerWaalsContact O-NE 3.14Å; E189-R226 PolarHBondContact O-NH2 3.45Å; Q222-R226 PolarHBondContact O-N 3.08Å; L223-R226 PolarHBondContact O-N 2.93Å; R226-S228 VanDerWaalsContact C-N 3.29Å; R226-S228 PolarHBondContact O-N 2.84Å; R226-E229 IonicContact CZ-OE2 2.8Å; R226-E229 IonicContact NH1-OE2 3.93Å; R226-E229 PolarHBondContact NH1-OE2 3.08Å; R226-E229 PolarHBondContact O-N 3.19Å; R226-V230 WeakPolarHBondContact O-CG2 3.24Å; R226-V230 PolarHBondContact O-N 3.35Å
227	S	94.8	Very high	93	Very high	0 Å²	0	47.6 Å²	47.6	0%	0	23%	0.232	C	C	.	.	H	α-helix	trans	-60.5	-38.7	174.2	-63.9	0	0	0	0	112.3	L223 A224 R225 R231	L223-S227 WeakPolarHBondContact O-CB 3.35Å; L223-S227 PolarHBondContact O-N 2.75Å; L223-S227 PolarHBondContact O-OG 3.45Å; L223-S227 VanDerWaalsContact O-OG 3.07Å; A224-S227 PolarHBondContact O-N 2.86Å; R225-S227 VanDerWaalsContact C-N 3.3Å; R225-S227 PolarHBondContact O-N 3.03Å; S227-R231 VanDerWaalsContact O-CB 3.25Å; S227-R231 WeakPolarHBondContact O-CB 3.43Å; S227-R231 PolarHBondContact O-N 3.24Å
228	S	94.3	Very high	92.5	Very high	1 Å²	1	54.1 Å²	54.1	1%	0.007	26%	0.263	C	S	.	.	H	α-helix	trans	-69.2	-37.3	177.4	73	0	0	0	0	112.8	C75 Q76 A224 R225 R226 R231 T232	C75-S228 WeakPolarHBondContact CA-OG 3.48Å; Q76-S228 PolarHBondContact N-OG 3.36Å; A224-S228 WeakPolarHBondContact O-CB 3.38Å; A224-S228 PolarHBondContact O-N 3.16Å; R225-S228 WeakPolarHBondContact O-CA 3.34Å; R225-S228 WeakPolarHBondContact O-CB 3.35Å; R225-S228 PolarHBondContact O-N 3.03Å; R225-S228 PolarHBondContact O-OG 3.4Å; R226-S228 VanDerWaalsContact C-N 3.29Å; R226-S228 PolarHBondContact O-N 2.84Å; S228-R231 WeakPolarHBondContact O-CB 3.45Å; S228-R231 PolarHBondContact O-N 3.1Å; S228-T232 WeakPolarHBondContact O-CG2 3.45Å; S228-T232 PolarHBondContact O-N 3.22Å; S228-T232 PolarHBondContact O-OG1 3.25Å
229	E	93.6	Very high	92.3	Very high	74 Å²	74	53.6 Å²	53.6	35%	0.346	26%	0.256	S	S	.	.	H	α-helix	trans	-65.8	-44.5	175.4	-68.9	167.9	-170.4	0	0	112	Q76 R225 R226 R231 T232 N233	Q76-E229 HydrophobicContact CG-CG 4.32Å; R225-E229 WeakPolarHBondContact O-CG 3.3Å; R225-E229 PolarHBondContact O-N 2.91Å; R226-E229 IonicContact CZ-OE2 2.8Å; R226-E229 IonicContact NH1-OE2 3.93Å; R226-E229 PolarHBondContact NH1-OE2 3.08Å; R226-E229 PolarHBondContact O-N 3.19Å; E229-R231 VanDerWaalsContact C-N 3.3Å; E229-R231 PolarHBondContact O-N 3.44Å; E229-T232 PolarHBondContact O-N 3.29Å; E229-T232 PolarHBondContact O-OG1 3.39Å; E229-N233 PolarHBondContact O-N 3.42Å; E229-N233 PolarHBondContact O-ND2 3.33Å
230	V	93	Very high	92	Very high	15 Å²	15	60.6 Å²	60.6	9%	0.091	29%	0.288	C	S	.	.	H	α-helix	trans	-64.8	-40	176.3	176.4	0	0	0	0	110.1	F188 F193 R226 T232 N233 L245	F188-V230 HydrophobicContact CE2-CG2 3.99Å; F188-V230 HydrophobicContact CZ-CB 4.41Å; F188-V230 HydrophobicContact CZ-CG2 3.79Å; F193-V230 HydrophobicContact CB-CG1 4.39Å; R226-V230 WeakPolarHBondContact O-CG2 3.24Å; R226-V230 PolarHBondContact O-N 3.35Å; V230-T232 VanDerWaalsContact C-N 3.33Å; V230-T232 PolarHBondContact O-N 3.23Å; V230-N233 PolarHBondContact O-N 3.41Å; V230-L245 HydrophobicContact CB-CD1 4.26Å; V230-L245 HydrophobicContact CB-CD2 4.38Å; V230-L245 HydrophobicContact CG1-CD1 3.84Å; V230-L245 HydrophobicContact CG1-CD2 4.42Å
231	R	93.6	Very high	91.8	Very high	0 Å²	0	64.2 Å²	64.2	0%	0	30%	0.301	C	S	.	.	H	α-helix	trans	-60.4	-38.8	176.4	-179	179.4	66.2	-179.3	1.3	112.8	Q76 S227 S228 E229 N233 L234 L242 L245 N246 D263	Q76-R231 PolarHBondContact O-NH2 2.83Å; Q76-R231 VanDerWaalsContact O-NH2 3.11Å; S227-R231 VanDerWaalsContact O-CB 3.25Å; S227-R231 WeakPolarHBondContact O-CB 3.43Å; S227-R231 PolarHBondContact O-N 3.24Å; S228-R231 WeakPolarHBondContact O-CB 3.45Å; S228-R231 PolarHBondContact O-N 3.1Å; E229-R231 VanDerWaalsContact C-N 3.3Å; E229-R231 PolarHBondContact O-N 3.44Å; R231-N233 PolarHBondContact O-N 2.6Å; R231-L234 WeakPolarHBondContact O-CB 3.27Å; R231-L234 PolarHBondContact O-N 3.17Å; R231-L242 HydrophobicContact CG-CD1 3.87Å; R231-L245 HydrophobicContact CB-CD1 4.25Å; R231-N246 WeakPolarHBondContact CD-OD1 3.41Å; R231-N246 PolarHBondContact NH1-OD1 3.32Å; R231-D263 IonicContact CZ-OD1 3.23Å; R231-D263 IonicContact CZ-OD2 3.38Å; R231-D263 IonicContact NH1-OD1 2.71Å; R231-D263 PolarHBondContact NH1-OD1 2.97Å; R231-D263 VanDerWaalsContact NH1-OD1 3.14Å; R231-D263 IonicContact NH1-OD2 2.73Å; R231-D263 PolarHBondContact NH1-OD2 3.2Å; R231-D263 IonicContact NH2-OD1 3.39Å; R231-D263 PolarHBondContact NH2-OD1 2.76Å; R231-D263 IonicContact NH2-OD2 3.14Å
232	T	91.4	Very high	91.6	Very high	52 Å²	52	62.9 Å²	62.9	32%	0.319	30%	0.297	S	S	.	.	H	α-helix	trans	-68.1	-21.7	178.6	46.3	0	0	0	0	113.8	Q76 P79 S228 E229 V230 L234	Q76-T232 HydrophobicContact CB-CG2 3.76Å; P79-T232 HydrophobicContact CG-CG2 4.48Å; S228-T232 WeakPolarHBondContact O-CG2 3.45Å; S228-T232 PolarHBondContact O-N 3.22Å; S228-T232 PolarHBondContact O-OG1 3.25Å; E229-T232 PolarHBondContact O-N 3.29Å; E229-T232 PolarHBondContact O-OG1 3.39Å; V230-T232 VanDerWaalsContact C-N 3.33Å; V230-T232 PolarHBondContact O-N 3.23Å; T232-L234 VanDerWaalsContact C-N 3.32Å
233	N	90.6	Very high	91.5	Very high	127 Å²	127	63.9 Å²	63.9	68%	0.679	31%	0.311	S	S	*	.	T	Hydrogen-bonded Turn	trans	-88.1	0.3	178.3	-63.6	-23.1	0	0	0	113	E229 V230 R231	E229-N233 PolarHBondContact O-N 3.42Å; E229-N233 PolarHBondContact O-ND2 3.33Å; V230-N233 PolarHBondContact O-N 3.41Å; R231-N233 PolarHBondContact O-N 2.6Å
234	L	89.8	Confident	91.5	Very high	12 Å²	12	65.7 Å²	65.7	6%	0.063	32%	0.322	C	S	.	.			trans	-79.7	132.2	177.9	-59.7	-179	0	0	0	110.8	F82 R231 T232 D239 R241 L242 L245	F82-L234 HydrophobicContact CE1-CB 3.97Å; R231-L234 WeakPolarHBondContact O-CB 3.27Å; R231-L234 PolarHBondContact O-N 3.17Å; T232-L234 VanDerWaalsContact C-N 3.32Å; L234-D239 HydrophobicContact CD1-CB 4.46Å; L234-D239 WeakPolarHBondContact CD2-OD2 3.32Å; L234-R241 VanDerWaalsContact CD2-NH2 3.31Å; L234-L242 HydrophobicContact CD1-CB 4.04Å; L234-L242 HydrophobicContact CD1-CD1 4.22Å; L234-L245 HydrophobicContact CD1-CD1 4.09Å
235	E	86.6	Confident	91.4	Very high	168 Å²	168	65.7 Å²	65.7	79%	0.785	32%	0.322	S	S	*	.			trans	-86.2	-29.3	-179.2	-60.2	-175.4	167.3	0	0	112.6
236	H	88.3	Confident	91.5	Very high	126 Å²	126	64.6 Å²	64.6	58%	0.583	32%	0.319	S	S	*	.			trans	-126.5	142.6	-170.6	-58.9	-53.5	0	0	0	112.5	E238 D239	H236-E238 PolarHBondContact O-N 2.85Å; H236-D239 WeakPolarHBondContact O-CB 3.09Å; H236-D239 PolarHBondContact O-N 2.93Å
237	Q	85.3	Confident	91.6	Very high	115 Å²	115	63.4 Å²	63.4	54%	0.537	32%	0.317	S	S	.	.	T	Hydrogen-bonded Turn	trans	-70.8	-19.4	175.4	-68	-179.8	3	0	0	112.9	F82 D239 L242	F82-Q237 HydrophobicContact CD2-CG 3.84Å; F82-Q237 HydrophobicContact CE1-CG 4.31Å; F82-Q237 HydrophobicContact CE2-CG 3.5Å; F82-Q237 VanDerWaalsContact CE2-CG 3.5Å; F82-Q237 HydrophobicContact CG-CG 4.39Å; F82-Q237 HydrophobicContact CZ-CG 3.76Å; Q237-D239 VanDerWaalsContact C-N 3.27Å; Q237-L242 WeakPolarHBondContact O-CD2 3.23Å
238	E	84.8	Confident	91.7	Very high	187 Å²	187	63.5 Å²	63.5	87%	0.874	32%	0.317	S	S	*	.	T	Hydrogen-bonded Turn	trans	-85.1	-0.1	179.8	-65	171.2	-172.3	0	0	112.6	H236 E240	H236-E238 PolarHBondContact O-N 2.85Å; E238-E240 PolarHBondContact O-N 3.26Å
239	D	88.8	Confident	91.7	Very high	41 Å²	41	63.5 Å²	63.5	22%	0.219	32%	0.317	C	S	.	.			trans	-62.7	124.4	176.5	-166.6	-53.4	0	0	0	110.4	L234 H236 Q237 R241 L242	L234-D239 HydrophobicContact CD1-CB 4.46Å; L234-D239 WeakPolarHBondContact CD2-OD2 3.32Å; H236-D239 WeakPolarHBondContact O-CB 3.09Å; H236-D239 PolarHBondContact O-N 2.93Å; Q237-D239 VanDerWaalsContact C-N 3.27Å; D239-R241 PolarHBondContact O-N 3.46Å; D239-R241 WeakPolarHBondContact OD1-CB 3.4Å; D239-R241 WeakPolarHBondContact OD1-CG 3.28Å; D239-R241 IonicContact OD1-CZ 3.15Å; D239-R241 PolarHBondContact OD1-N 3Å; D239-R241 IonicContact OD1-NE 2.66Å; D239-R241 PolarHBondContact OD1-NE 3.48Å; D239-R241 IonicContact OD1-NH2 3.98Å; D239-R241 IonicContact OD2-CZ 3.97Å; D239-R241 IonicContact OD2-NE 2.96Å; D239-R241 PolarHBondContact OD2-NE 3.5Å; D239-R241 IonicContact OD2-NH2 3.86Å; D239-R241 PolarHBondContact OD2-NH2 3.28Å; D239-L242 WeakPolarHBondContact O-CB 3.43Å; D239-L242 PolarHBondContact O-N 3.17Å
240	E	89.3	Confident	91.9	Very high	166 Å²	166	60.1 Å²	60.1	78%	0.776	30%	0.301	S	S	*	.	T	Hydrogen-bonded Turn	trans	-57.7	-23.3	-178.5	-61.8	-170.1	161	0	0	112.9	E238 P244	E238-E240 PolarHBondContact O-N 3.26Å; E240-P244 WeakPolarHBondContact O-CD 3.35Å
241	R	90.4	Very high	92.1	Very high	77 Å²	77	59.4 Å²	59.4	29%	0.291	30%	0.297	S	S	.	.	T	Hydrogen-bonded Turn	trans	-76.5	-22.3	179.9	-56.3	174.8	-70.3	-179.2	0.4	112.5	F193 L234 D239 S243 P244 L245	F193-R241 HydrophobicContact CD1-CB 4.09Å; F193-R241 HydrophobicContact CD1-CG 4.02Å; L234-R241 VanDerWaalsContact CD2-NH2 3.31Å; D239-R241 PolarHBondContact O-N 3.46Å; D239-R241 WeakPolarHBondContact OD1-CB 3.4Å; D239-R241 WeakPolarHBondContact OD1-CG 3.28Å; D239-R241 IonicContact OD1-CZ 3.15Å; D239-R241 PolarHBondContact OD1-N 3Å; D239-R241 IonicContact OD1-NE 2.66Å; D239-R241 PolarHBondContact OD1-NE 3.48Å; D239-R241 IonicContact OD1-NH2 3.98Å; D239-R241 IonicContact OD2-CZ 3.97Å; D239-R241 IonicContact OD2-NE 2.96Å; D239-R241 PolarHBondContact OD2-NE 3.5Å; D239-R241 IonicContact OD2-NH2 3.86Å; D239-R241 PolarHBondContact OD2-NH2 3.28Å; R241-S243 PolarHBondContact O-N 2.96Å; R241-P244 WeakPolarHBondContact O-CD 3.39Å; R241-L245 HydrophobicContact CB-CD1 4.19Å; R241-L245 WeakPolarHBondContact O-CB 3.46Å; R241-L245 WeakPolarHBondContact O-CD1 3.35Å; R241-L245 WeakPolarHBondContact O-CG 3.16Å; R241-L245 PolarHBondContact O-N 3.1Å; R241-L245 VanDerWaalsContact O-N 3.1Å
242	L	93.1	Very high	92.2	Very high	13 Å²	13	59.4 Å²	59.4	7%	0.068	30%	0.297	C	S	.	.	H	α-helix	trans	-60.3	-48.1	-176.3	178.5	55.8	0	0	0	112.1	F82 R231 L234 Q237 D239 L245 N246	F82-L242 HydrophobicContact CB-CD1 4.14Å; F82-L242 HydrophobicContact CB-CD2 4.45Å; F82-L242 HydrophobicContact CD1-CD1 3.7Å; F82-L242 HydrophobicContact CD1-CD2 3.69Å; F82-L242 HydrophobicContact CD1-CG 4.32Å; F82-L242 HydrophobicContact CE1-CD2 4.25Å; F82-L242 HydrophobicContact CG-CD1 4.38Å; F82-L242 HydrophobicContact CG-CD2 4.25Å; R231-L242 HydrophobicContact CG-CD1 3.87Å; L234-L242 HydrophobicContact CD1-CB 4.04Å; L234-L242 HydrophobicContact CD1-CD1 4.22Å; Q237-L242 WeakPolarHBondContact O-CD2 3.23Å; D239-L242 WeakPolarHBondContact O-CB 3.43Å; D239-L242 PolarHBondContact O-N 3.17Å; L242-L245 PolarHBondContact O-N 3.32Å; L242-N246 WeakPolarHBondContact CD1-ND2 3.38Å; L242-N246 WeakPolarHBondContact O-CB 3.4Å; L242-N246 PolarHBondContact O-N 3.15Å
243	S	93	Very high	92.4	Very high	79 Å²	79	56.9 Å²	56.9	55%	0.552	28%	0.282	S	S	*	.	H	α-helix	trans	-63.2	-48.4	-177.5	-70.8	0	0	0	0	112.8	R241 L245 N246 L247	R241-S243 PolarHBondContact O-N 2.96Å; S243-L245 PolarHBondContact O-N 3.15Å; S243-N246 PolarHBondContact O-N 2.66Å; S243-L247 WeakPolarHBondContact O-CB 3.48Å; S243-L247 PolarHBondContact O-N 3.41Å
244	P	95.1	Very high	92.7	Very high	38 Å²	38	55 Å²	55	25%	0.247	27%	0.265	C	S	.	.	H	α-helix	trans	-57.9	-43.4	172.3	-26.7	33.9	0	0	0	114.3	F193 E240 R241 L247 M248	F193-P244 HydrophobicContact CE1-CB 3.62Å; F193-P244 HydrophobicContact CE1-CG 4.12Å; F193-P244 HydrophobicContact CZ-CB 3.53Å; F193-P244 HydrophobicContact CZ-CG 4.46Å; E240-P244 WeakPolarHBondContact O-CD 3.35Å; R241-P244 WeakPolarHBondContact O-CD 3.39Å; P244-L247 WeakPolarHBondContact O-CB 3.42Å; P244-L247 PolarHBondContact O-N 3.09Å; P244-M248 WeakPolarHBondContact O-CG 3.14Å; P244-M248 PolarHBondContact O-N 3.2Å
245	L	95.3	Very high	92.9	Very high	0 Å²	0	56.1 Å²	56.1	0%	0	27%	0.269	C	S	.	.	H	α-helix	trans	-64.4	-45.1	-179.4	-66.8	167.9	0	0	0	111.3	F188 F193 V230 R231 L234 R241 L242 S243 L247 M248 I249	F188-L245 HydrophobicContact CZ-CD2 4.17Å; F193-L245 HydrophobicContact CD2-CD2 3.86Å; F193-L245 HydrophobicContact CE2-CD2 4.2Å; F193-L245 HydrophobicContact CG-CD2 4.1Å; V230-L245 HydrophobicContact CB-CD1 4.26Å; V230-L245 HydrophobicContact CB-CD2 4.38Å; V230-L245 HydrophobicContact CG1-CD1 3.84Å; V230-L245 HydrophobicContact CG1-CD2 4.42Å; R231-L245 HydrophobicContact CB-CD1 4.25Å; L234-L245 HydrophobicContact CD1-CD1 4.09Å; R241-L245 HydrophobicContact CB-CD1 4.19Å; R241-L245 WeakPolarHBondContact O-CB 3.46Å; R241-L245 WeakPolarHBondContact O-CD1 3.35Å; R241-L245 WeakPolarHBondContact O-CG 3.16Å; R241-L245 PolarHBondContact O-N 3.1Å; R241-L245 VanDerWaalsContact O-N 3.1Å; L242-L245 PolarHBondContact O-N 3.32Å; S243-L245 PolarHBondContact O-N 3.15Å; L245-L247 VanDerWaalsContact C-N 3.3Å; L245-L247 PolarHBondContact O-N 3.09Å; L245-M248 PolarHBondContact O-N 3.13Å; L245-I249 WeakPolarHBondContact O-CG1 3.3Å; L245-I249 PolarHBondContact O-N 3.14Å; L245-I249 VanDerWaalsContact O-N 3.11Å
246	N	95.5	Very high	93.4	Very high	9 Å²	9	48.1 Å²	48.1	5%	0.048	23%	0.232	C	C	.	.	H	α-helix	trans	-61.2	-38.3	174.2	-79.1	-15.4	0	0	0	112.1	F82 P84 W88 R231 L242 S243 C250	F82-N246 PolarHBondContact O-ND2 3Å; P84-N246 HydrophobicContact CG-CB 4.15Å; W88-N246 HydrophobicContact CH2-CB 4.31Å; W88-N246 HydrophobicContact CZ3-CB 4.49Å; R231-N246 WeakPolarHBondContact CD-OD1 3.41Å; R231-N246 PolarHBondContact NH1-OD1 3.32Å; L242-N246 WeakPolarHBondContact CD1-ND2 3.38Å; L242-N246 WeakPolarHBondContact O-CB 3.4Å; L242-N246 PolarHBondContact O-N 3.15Å; S243-N246 PolarHBondContact O-N 2.66Å; N246-C250 WeakPolarHBondContact O-CB 3.17Å; N246-C250 PolarHBondContact O-N 2.86Å
247	L	96.7	Very high	93.6	Very high	31 Å²	31	46.8 Å²	46.8	16%	0.162	23%	0.229	C	C	.	.	H	α-helix	trans	-64.2	-45.8	176.5	179.1	61	0	0	0	111.5	W88 Q92 Y202 S243 P244 L245 C250 L251	W88-L247 HydrophobicContact CH2-CB 4.03Å; W88-L247 HydrophobicContact CH2-CD1 4.31Å; Q92-L247 HydrophobicContact CB-CD1 3.82Å; Q92-L247 HydrophobicContact CG-CD1 3.91Å; Y202-L247 HydrophobicContact CD2-CD2 3.9Å; Y202-L247 HydrophobicContact CD2-CG 4.41Å; Y202-L247 HydrophobicContact CE2-CD1 4.48Å; Y202-L247 HydrophobicContact CE2-CD2 3.81Å; Y202-L247 HydrophobicContact CE2-CG 4.31Å; S243-L247 WeakPolarHBondContact O-CB 3.48Å; S243-L247 PolarHBondContact O-N 3.41Å; P244-L247 WeakPolarHBondContact O-CB 3.42Å; P244-L247 PolarHBondContact O-N 3.09Å; L245-L247 VanDerWaalsContact C-N 3.3Å; L245-L247 PolarHBondContact O-N 3.09Å; L247-C250 PolarHBondContact O-N 2.81Å; L247-L251 HydrophobicContact CD1-CD1 4.19Å; L247-L251 HydrophobicContact CD1-CD2 4.44Å; L247-L251 HydrophobicContact CD1-CG 4.08Å; L247-L251 HydrophobicContact CG-CD1 4.29Å; L247-L251 VanDerWaalsContact O-CG 3.32Å; L247-L251 WeakPolarHBondContact O-CG 3.19Å; L247-L251 PolarHBondContact O-N 3.46Å
248	M	96.4	Very high	94	Very high	3 Å²	3	42.6 Å²	42.6	2%	0.015	21%	0.209	C	C	.	.	H	α-helix	trans	-59.8	-50.3	178.1	-67	-57.4	162.8	0	0	111.5	G198 Q201 L205 P244 L245 C250 L251 V252	G198-M248 WeakPolarHBondContact O-CE 3.41Å; Q201-M248 HydrophobicContact CB-CE 3.94Å; Q201-M248 HydrophobicContact CB-SD 4.2Å; L205-M248 HydrophobicContact CD1-SD 3.8Å; P244-M248 WeakPolarHBondContact O-CG 3.14Å; P244-M248 PolarHBondContact O-N 3.2Å; L245-M248 PolarHBondContact O-N 3.13Å; M248-C250 VanDerWaalsContact C-N 3.32Å; M248-C250 PolarHBondContact O-N 2.83Å; M248-L251 PolarHBondContact O-N 3Å; M248-V252 WeakPolarHBondContact O-CG2 3.21Å; M248-V252 PolarHBondContact O-N 3.31Å
249	I	96.3	Very high	94.4	Very high	0 Å²	0	38.1 Å²	38.1	0%	0	19%	0.191	C	C	.	.	H	α-helix	trans	-58.4	-46.5	177.8	-63.5	164.7	0	0	0	110.3	A224 L245 L251 V252 A253	A224-I249 HydrophobicContact CB-CG1 4.49Å; L245-I249 WeakPolarHBondContact O-CG1 3.3Å; L245-I249 PolarHBondContact O-N 3.14Å; L245-I249 VanDerWaalsContact O-N 3.11Å; I249-L251 PolarHBondContact O-N 3.09Å; I249-V252 PolarHBondContact O-N 3.18Å; I249-A253 VanDerWaalsContact O-CB 3.22Å; I249-A253 WeakPolarHBondContact O-CB 3.21Å; I249-A253 PolarHBondContact O-N 3.1Å
250	C	96.9	Very high	94.6	Very high	3 Å²	3	41 Å²	41	2%	0.02	21%	0.206	C	C	.	.	H	α-helix	trans	-58.9	-46.5	179	178.6	0	0	0	0	112.4	W88 Q89 N246 L247 M248 R254	W88-C250 HydrophobicContact CZ3-CB 4.2Å; Q89-C250 VanDerWaalsContact CA-SG 3.53Å; Q89-C250 VanDerWaalsContact CB-SG 3.55Å; Q89-C250 HydrophobicContact CG-CB 4.49Å; N246-C250 WeakPolarHBondContact O-CB 3.17Å; N246-C250 PolarHBondContact O-N 2.86Å; L247-C250 PolarHBondContact O-N 2.81Å; M248-C250 VanDerWaalsContact C-N 3.32Å; M248-C250 PolarHBondContact O-N 2.83Å; C250-R254 VanDerWaalsContact O-CB 3.28Å; C250-R254 WeakPolarHBondContact O-CB 3.41Å; C250-R254 PolarHBondContact O-N 3.07Å
251	L	97	Very high	94.8	Very high	0 Å²	0	33.2 Å²	33.2	0%	0	17%	0.17	C	C	.	.	I	π-helix	trans	-66.2	-45.6	-179.8	-67.6	-178.6	0	0	0	111.4	F96 Y202 L247 M248 I249 A253 Y255 F256	F96-L251 HydrophobicContact CB-CD2 3.62Å; F96-L251 HydrophobicContact CD1-CD1 4.43Å; F96-L251 HydrophobicContact CD1-CD2 3.8Å; F96-L251 HydrophobicContact CD2-CD1 3.76Å; F96-L251 HydrophobicContact CD2-CD2 4.14Å; F96-L251 HydrophobicContact CE1-CD1 4.45Å; F96-L251 HydrophobicContact CE1-CD2 4.43Å; F96-L251 HydrophobicContact CE2-CD1 3.79Å; F96-L251 HydrophobicContact CG-CD1 4.07Å; F96-L251 HydrophobicContact CG-CD2 3.6Å; F96-L251 HydrophobicContact CG-CG 4.47Å; F96-L251 HydrophobicContact CZ-CD1 4.14Å; Y202-L251 HydrophobicContact CD2-CD1 3.8Å; Y202-L251 HydrophobicContact CE2-CD1 3.65Å; L247-L251 HydrophobicContact CD1-CD1 4.19Å; L247-L251 HydrophobicContact CD1-CD2 4.44Å; L247-L251 HydrophobicContact CD1-CG 4.08Å; L247-L251 HydrophobicContact CG-CD1 4.29Å; L247-L251 VanDerWaalsContact O-CG 3.32Å; L247-L251 WeakPolarHBondContact O-CG 3.19Å; L247-L251 PolarHBondContact O-N 3.46Å; M248-L251 PolarHBondContact O-N 3Å; I249-L251 PolarHBondContact O-N 3.09Å; L251-A253 VanDerWaalsContact C-N 3.35Å; L251-A253 PolarHBondContact O-N 3.45Å; L251-Y255 CarbonylContact O-C 3.56Å; L251-Y255 VanDerWaalsContact O-CA 3.3Å; L251-Y255 WeakPolarHBondContact O-CA 3.47Å; L251-Y255 WeakPolarHBondContact O-CB 3.26Å; L251-Y255 PolarHBondContact O-N 3.15Å; L251-F256 WeakPolarHBondContact O-CD2 3.27Å; L251-F256 PolarHBondContact O-N 3.14Å
252	V	96.6	Very high	94.8	Very high	0 Å²	0	30.2 Å²	30.2	0%	0	16%	0.162	C	C	.	.	I	π-helix	trans	-59.6	-48.9	177.1	174.3	0	0	0	0	110.6	I220 A224 M248 I249 F256 Q258 L261	I220-V252 HydrophobicContact CB-CG1 4.26Å; I220-V252 HydrophobicContact CB-CG2 3.98Å; I220-V252 HydrophobicContact CD1-CG1 4.28Å; I220-V252 HydrophobicContact CG1-CG1 4.04Å; I220-V252 WeakPolarHBondContact O-CG1 3.47Å; I220-V252 WeakPolarHBondContact O-CG2 3.5Å; A224-V252 HydrophobicContact CB-CB 3.96Å; A224-V252 HydrophobicContact CB-CG1 3.83Å; A224-V252 HydrophobicContact CB-CG2 4.23Å; M248-V252 WeakPolarHBondContact O-CG2 3.21Å; M248-V252 PolarHBondContact O-N 3.31Å; I249-V252 PolarHBondContact O-N 3.18Å; V252-F256 CarbonylContact O-C 3.33Å; V252-Q258 HydrophobicContact CG1-CB 4.12Å; V252-Q258 HydrophobicContact CG1-CG 4.01Å; V252-Q258 WeakPolarHBondContact O-CB 3.18Å; V252-Q258 PolarHBondContact O-N 3.16Å; V252-L261 HydrophobicContact CG1-CD1 4.33Å
253	A	95.7	Very high	94.7	Very high	0 Å²	0	30.1 Å²	30.1	0%	0	16%	0.162	C	C	.	.	I	π-helix	trans	-72.5	-41.8	-173.4	0	0	0	0	0	113.7	I249 L251 Q258 N259 L261 A262	I249-A253 VanDerWaalsContact O-CB 3.22Å; I249-A253 WeakPolarHBondContact O-CB 3.21Å; I249-A253 PolarHBondContact O-N 3.1Å; L251-A253 VanDerWaalsContact C-N 3.35Å; L251-A253 PolarHBondContact O-N 3.45Å; A253-Q258 VanDerWaalsContact CA-O 3.26Å; A253-Q258 WeakPolarHBondContact CA-O 3.34Å; A253-Q258 CarbonylContact O-C 3.59Å; A253-Q258 PolarHBondContact O-N 3.25Å; A253-Q258 VanDerWaalsContact O-N 3.1Å; A253-N259 PolarHBondContact O-N 3.42Å; A253-N259 PolarHBondContact O-OD1 2.98Å; A253-L261 HydrophobicContact CB-CB 4.32Å; A253-A262 VanDerWaalsContact CB-CA 3.43Å; A253-A262 HydrophobicContact CB-CB 3.72Å
254	R	95	Very high	94.1	Very high	88 Å²	88	34.4 Å²	34.4	33%	0.332	17%	0.17	S	C	.	.	I	π-helix	trans	-102	-39.3	-172.5	-59.1	-65.7	-167.5	173.8	-1.9	113.6	V93 C250	V93-R254 HydrophobicContact CG2-CB 3.55Å; V93-R254 HydrophobicContact CG2-CG 4.45Å; C250-R254 VanDerWaalsContact O-CB 3.28Å; C250-R254 WeakPolarHBondContact O-CB 3.41Å; C250-R254 PolarHBondContact O-N 3.07Å
255	Y	95.8	Very high	92.8	Very high	35 Å²	35	37.9 Å²	37.9	14%	0.137	18%	0.183	C	C	.	.	I	π-helix	trans	-84.3	-37.5	-178.5	-171.8	-87.9	0	0	0	112.1	V93 F96 R100 K210 L251	V93-Y255 HydrophobicContact CG1-CD2 3.99Å; F96-Y255 AromaticContact CD1-CD1 3.6Å; F96-Y255 HydrophobicContact CD1-CD1 3.6Å; F96-Y255 AromaticContact CD1-CD2 3.61Å; F96-Y255 HydrophobicContact CD1-CD2 3.61Å; F96-Y255 AromaticContact CD1-CE1 3.75Å; F96-Y255 HydrophobicContact CD1-CE1 3.75Å; F96-Y255 AromaticContact CD1-CE2 3.76Å; F96-Y255 HydrophobicContact CD1-CE2 3.76Å; F96-Y255 AromaticContact CD1-CG 3.53Å; F96-Y255 HydrophobicContact CD1-CG 3.53Å; F96-Y255 AromaticContact CD1-CZ 3.83Å; F96-Y255 AromaticContact CE1-CD1 3.44Å; F96-Y255 HydrophobicContact CE1-CD1 3.44Å; F96-Y255 VanDerWaalsContact CE1-CD1 3.44Å; F96-Y255 HydrophobicContact CE1-CD2 4.32Å; F96-Y255 AromaticContact CE1-CE1 3.54Å; F96-Y255 HydrophobicContact CE1-CE1 3.54Å; F96-Y255 HydrophobicContact CE1-CE2 4.41Å; F96-Y255 AromaticContact CE1-CG 3.86Å; F96-Y255 HydrophobicContact CE1-CG 3.86Å; R100-Y255 VanDerWaalsContact CD-OH 3.23Å; R100-Y255 WeakPolarHBondContact CD-OH 3.34Å; R100-Y255 PolarHBondContact NE-OH 3.49Å; R100-Y255 VanDerWaalsContact NE-OH 3.16Å; K210-Y255 WeakPolarHBondContact CE-O 3.45Å; K210-Y255 PolarHBondContact NZ-O 2.47Å; L251-Y255 CarbonylContact O-C 3.56Å; L251-Y255 VanDerWaalsContact O-CA 3.3Å; L251-Y255 WeakPolarHBondContact O-CA 3.47Å; L251-Y255 WeakPolarHBondContact O-CB 3.26Å; L251-Y255 PolarHBondContact O-N 3.15Å
256	F	95.6	Very high	90.9	Very high	0 Å²	0	47.2 Å²	47.2	0%	0	23%	0.233	C	C	.	.	S	Bend	trans	-98.6	21.2	176.9	-62.3	-79.6	0	0	0	113.5	F96 L205 L208 L212 H217 I220 L251 V252 Q258	F96-F256 HydrophobicContact CE1-CE2 4.01Å; F96-F256 HydrophobicContact CE1-CZ 4.04Å; F96-F256 HydrophobicContact CZ-CE2 4.31Å; F96-F256 HydrophobicContact CZ-CZ 4.31Å; L205-F256 HydrophobicContact CB-CE2 4.21Å; L205-F256 HydrophobicContact CB-CZ 4.27Å; L205-F256 HydrophobicContact CD2-CE2 3.83Å; L205-F256 HydrophobicContact CD2-CZ 4.13Å; L205-F256 HydrophobicContact CG-CE2 4.47Å; L205-F256 WeakPolarHBondContact O-CZ 3.09Å; L208-F256 HydrophobicContact CD2-CE1 3.93Å; L212-F256 HydrophobicContact CD1-CD1 3.8Å; L212-F256 HydrophobicContact CD1-CE1 4.03Å; L212-F256 HydrophobicContact CD2-CD1 3.77Å; L212-F256 HydrophobicContact CD2-CE1 4.28Å; L212-F256 HydrophobicContact CG-CD1 4.47Å; H217-F256 PolarHBondContact CE1-O 3.16Å; I220-F256 HydrophobicContact CD1-CB 3.44Å; I220-F256 VanDerWaalsContact CD1-CB 3.44Å; I220-F256 HydrophobicContact CD1-CD1 4.24Å; I220-F256 HydrophobicContact CD1-CD2 4.16Å; I220-F256 HydrophobicContact CD1-CG 3.71Å; L251-F256 WeakPolarHBondContact O-CD2 3.27Å; L251-F256 PolarHBondContact O-N 3.14Å; V252-F256 CarbonylContact O-C 3.33Å; F256-Q258 PolarHBondContact O-N 2.84Å; F256-Q258 VanDerWaalsContact O-N 3.15Å; F256-Q258 PolarHBondContact O-NE2 3.41Å
257	D	93.9	Very high	90.7	Very high	98 Å²	98	49.2 Å²	49.2	52%	0.524	24%	0.242	S	C	.	.	S	Bend	trans	65	18	167.5	-50.6	-63.8	0	0	0	114.9	K210 N259	K210-D257 IonicContact NZ-OD2 2.86Å; K210-D257 PolarHBondContact NZ-OD2 3.47Å; D257-N259 VanDerWaalsContact C-N 3.29Å; D257-N259 PolarHBondContact O-N 2.95Å; D257-N259 VanDerWaalsContact O-N 3.15Å
258	Q	93.6	Very high	90.4	Very high	27 Å²	27	50.1 Å²	50.1	13%	0.126	25%	0.247	C	C	.	.			trans	-87.7	56.2	176.9	-52.8	-53.9	-66.2	0	0	112.3	H217 R221 V252 A253 F256 D260 L261	H217-Q258 PolarHBondContact CE1-NE2 3.42Å; H217-Q258 VanDerWaalsContact CE1-NE2 3.35Å; H217-Q258 PolarHBondContact ND1-NE2 3.13Å; R221-Q258 VanDerWaalsContact CD-OE1 3.24Å; R221-Q258 HydrophobicContact CG-CG 3.97Å; V252-Q258 HydrophobicContact CG1-CB 4.12Å; V252-Q258 HydrophobicContact CG1-CG 4.01Å; V252-Q258 WeakPolarHBondContact O-CB 3.18Å; V252-Q258 PolarHBondContact O-N 3.16Å; A253-Q258 VanDerWaalsContact CA-O 3.26Å; A253-Q258 WeakPolarHBondContact CA-O 3.34Å; A253-Q258 CarbonylContact O-C 3.59Å; A253-Q258 PolarHBondContact O-N 3.25Å; A253-Q258 VanDerWaalsContact O-N 3.1Å; F256-Q258 PolarHBondContact O-N 2.84Å; F256-Q258 VanDerWaalsContact O-N 3.15Å; F256-Q258 PolarHBondContact O-NE2 3.41Å; Q258-D260 PolarHBondContact O-N 3.26Å; Q258-L261 HydrophobicContact CB-CD1 4.22Å; Q258-L261 HydrophobicContact CB-CG 4.48Å; Q258-L261 PolarHBondContact O-N 3.24Å
259	N	92.3	Very high	90	Very high	92 Å²	92	52.7 Å²	52.7	49%	0.492	26%	0.259	S	S	.	.	G	3₁₀ helix	trans	-60.9	-20.9	-169.4	-71.5	-60.1	0	0	0	114.8	A253 D257 L261 A262	A253-N259 PolarHBondContact O-N 3.42Å; A253-N259 PolarHBondContact O-OD1 2.98Å; D257-N259 VanDerWaalsContact C-N 3.29Å; D257-N259 PolarHBondContact O-N 2.95Å; D257-N259 VanDerWaalsContact O-N 3.15Å; N259-L261 PolarHBondContact O-N 2.9Å; N259-A262 WeakPolarHBondContact O-CB 3.37Å; N259-A262 PolarHBondContact O-N 3.45Å
260	D	92.8	Very high	89.7	Confident	102 Å²	102	55.8 Å²	55.8	55%	0.545	28%	0.275	S	S	.	.	G	3₁₀ helix	trans	-67	-20	175.5	66.4	-55.7	0	0	0	113.1	R221 Q258	R221-D260 IonicContact CZ-OD1 2.72Å; R221-D260 IonicContact CZ-OD2 3.77Å; R221-D260 IonicContact NH1-OD1 3.78Å; R221-D260 PolarHBondContact NH1-OD1 3.03Å; R221-D260 IonicContact NH1-OD2 2.8Å; R221-D260 PolarHBondContact NH1-OD2 3.46Å; R221-D260 VanDerWaalsContact NH1-OD2 3.17Å; R221-D260 IonicContact NH2-OD1 3.7Å; R221-D260 IonicContact NH2-OD2 3.83Å; R221-D260 PolarHBondContact NH2-OD2 2.83Å; Q258-D260 PolarHBondContact O-N 3.26Å
261	L	92.9	Very high	89.2	Confident	3 Å²	3	59.1 Å²	59.1	2%	0.016	29%	0.291	C	S	.	.	G	3₁₀ helix	trans	-96.6	0.2	177.7	-57.9	-177.3	0	0	0	113.4	C75 R221 A224 V252 A253 Q258 N259	C75-L261 HydrophobicContact CB-CD2 4.43Å; R221-L261 HydrophobicContact CB-CD1 3.87Å; R221-L261 HydrophobicContact CG-CD1 3.7Å; A224-L261 HydrophobicContact CB-CD1 4.16Å; V252-L261 HydrophobicContact CG1-CD1 4.33Å; A253-L261 HydrophobicContact CB-CB 4.32Å; Q258-L261 HydrophobicContact CB-CD1 4.22Å; Q258-L261 HydrophobicContact CB-CG 4.48Å; Q258-L261 PolarHBondContact O-N 3.24Å; N259-L261 PolarHBondContact O-N 2.9Å
262	A	91.8	Very high	88.7	Confident	14 Å²	14	63.1 Å²	63.1	12%	0.116	31%	0.31	C	S	.	.	P	Polyproline II helix	trans	-70.8	137.6	-175	0	0	0	0	0	111.9	A253 N259 K264	A253-A262 VanDerWaalsContact CB-CA 3.43Å; A253-A262 HydrophobicContact CB-CB 3.72Å; N259-A262 WeakPolarHBondContact O-CB 3.37Å; N259-A262 PolarHBondContact O-N 3.45Å; A262-K264 PolarHBondContact O-N 2.78Å
263	D	89.4	Confident	88.1	Confident	11 Å²	11	67.6 Å²	67.6	6%	0.059	33%	0.332	C	S	.	.	P	Polyproline II helix	trans	-63.1	122.9	164.4	-65.9	-46.4	0	0	0	109.4	Q89 R231	Q89-D263 PolarHBondContact NE2-O 3.45Å; R231-D263 IonicContact CZ-OD1 3.23Å; R231-D263 IonicContact CZ-OD2 3.38Å; R231-D263 IonicContact NH1-OD1 2.71Å; R231-D263 PolarHBondContact NH1-OD1 2.97Å; R231-D263 VanDerWaalsContact NH1-OD1 3.14Å; R231-D263 IonicContact NH1-OD2 2.73Å; R231-D263 PolarHBondContact NH1-OD2 3.2Å; R231-D263 IonicContact NH2-OD1 3.39Å; R231-D263 PolarHBondContact NH2-OD1 2.76Å; R231-D263 IonicContact NH2-OD2 3.14Å
264	K	82	Confident	87.5	Confident	168 Å²	168	72.8 Å²	72.8	73%	0.73	36%	0.358	S	S	*	.	P	Polyproline II helix	trans	-87.1	145.2	172.2	-61.8	179.9	-175.6	174.1	0	108	S83 A262	S83-K264 PolarHBondContact OG-O 3Å; A262-K264 PolarHBondContact O-N 2.78Å
265	E	67.1	Low	86.9	Confident	111 Å²	111	71.5 Å²	71.5	52%	0.519	36%	0.36	S	S	.	.	P	Polyproline II helix	trans	-67	133	165.2	-74.1	-178.5	151.5	0	0	107.6	L86	L86-E265 VanDerWaalsContact CB-CD 3.45Å; L86-E265 HydrophobicContact CB-CG 4.1Å; L86-E265 VanDerWaalsContact CB-OE1 3.25Å; L86-E265 WeakPolarHBondContact CB-OE1 3.41Å; L86-E265 PolarHBondContact N-OE1 2.73Å
266	D	55.6	Low	86.1	Confident	197 Å²	197	74.8 Å²	74.8	100%	1.053	38%	0.38	S	S	*	.			trans	-70.2	0	167.1	-69.4	-37.8	0	0	0	110.7

Retrieved 266 of 266 residues in 1825.8 ms (Link to these results)

U.S. Privacy Notice - Disclaimer / Registrations / Copyright Statement - Linking Policy - Notice of Privacy Practices (HIPAA) - Notice of Non‑Discrimination
© Copyright 2026 St. Jude Children's Research Hospital, a not-for-profit, section 501(c)(3).