A0A060WDP9_ONCMY Loading...

Solute carrier family 22 member 3

AlphaFold DB , UniProt , Accession A0A060WDP9, Species ONCMY (Oncorhynchus mykiss, Rainbow trout), Gene LOC110529598, Length 561 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M46.4Very low70.1Confident190 Ų19049.1 Ų49.194%0.93625%0.248SC*.  0136.60-89.9151.2164.300107.2
2T56.8Low70.9Confident37 Ų3745.9 Ų45.923%0.22724%0.237CC..  trans-86.7117.9173.947.70000107.8K317 L322T2-K317 HydrophobicContact CG2-CB 4.4Å; T2-K317 HydrophobicContact CG2-CD 3.49Å; T2-K317 VanDerWaalsContact CG2-CD 3.49Å; T2-K317 HydrophobicContact CG2-CG 3.91Å; T2-L322 WeakPolarHBondContact O-CD2 3.16Å
3T67.7Low71.3Confident51 Ų5145.1 Ų45.131%0.31323%0.233SC..  trans-71.8154.2179.759.70000110.8D5 E6 I7T3-D5 PolarHBondContact O-N 3.15Å; T3-E6 PolarHBondContact N-OE1 3.49Å; T3-E6 WeakPolarHBondContact O-CB 3.46Å; T3-E6 PolarHBondContact O-N 2.94Å; T3-E6 VanDerWaalsContact OG1-CD 3.23Å; T3-E6 VanDerWaalsContact OG1-CG 3.22Å; T3-E6 WeakPolarHBondContact OG1-CG 3.4Å; T3-E6 PolarHBondContact OG1-N 3.43Å; T3-E6 PolarHBondContact OG1-OE1 3.32Å; T3-I7 PolarHBondContact O-N 2.92Å
4F70.8Confident72.1Confident29 Ų2944 Ų4413%0.12723%0.226CC..Hα-helixtrans-58-37.5174.9176.9-87.6000111.7E6 I7 L8 P288 R289 L292 I304F4-E6 VanDerWaalsContact C-N 3.33Å; F4-E6 PolarHBondContact O-N 2.89Å; F4-I7 PolarHBondContact O-N 3.42Å; F4-L8 HydrophobicContact CE1-CB 4.24Å; F4-L8 HydrophobicContact CE1-CD2 4.13Å; F4-L8 PolarHBondContact O-N 3.25Å; F4-P288 HydrophobicContact CE2-CB 3.78Å; F4-P288 HydrophobicContact CZ-CB 3.85Å; F4-P288 HydrophobicContact CZ-CG 4.48Å; F4-R289 HydrophobicContact CD1-CG 3.47Å; F4-R289 VanDerWaalsContact CD1-CG 3.47Å; F4-R289 VanDerWaalsContact CD1-CZ 3.46Å; F4-R289 VanDerWaalsContact CD1-NE 3.33Å; F4-R289 HydrophobicContact CD2-CG 4.16Å; F4-R289 HydrophobicContact CE1-CG 3.21Å; F4-R289 VanDerWaalsContact CE1-NH2 3.34Å; F4-R289 HydrophobicContact CE2-CG 3.92Å; F4-R289 HydrophobicContact CG-CG 3.94Å; F4-R289 HydrophobicContact CZ-CG 3.45Å; F4-R289 VanDerWaalsContact CZ-CG 3.45Å; F4-L292 HydrophobicContact CD2-CD1 3.42Å; F4-L292 VanDerWaalsContact CD2-CD1 3.42Å; F4-L292 HydrophobicContact CE2-CD1 3.84Å; F4-I304 HydrophobicContact CE2-CD1 4Å
5D71.4Confident73.1Confident46 Ų4642.4 Ų42.425%0.24622%0.224CC..Hα-helixtrans-59.6-42.4177.9-75.7-54000111.4T3 I7 L8 E9 V232 R235 R289T3-D5 PolarHBondContact O-N 3.15Å; D5-I7 VanDerWaalsContact C-N 3.34Å; D5-I7 PolarHBondContact O-N 3.28Å; D5-L8 PolarHBondContact O-N 3.46Å; D5-E9 WeakPolarHBondContact O-CG 3.25Å; D5-E9 PolarHBondContact O-N 3.06Å; D5-V232 HydrophobicContact CB-CG2 4.11Å; D5-V232 VanDerWaalsContact OD1-CG2 3.29Å; D5-V232 WeakPolarHBondContact OD1-CG2 3.45Å; D5-R235 IonicContact OD1-CZ 2.75Å; D5-R235 IonicContact OD1-NH2 2.77Å; D5-R235 PolarHBondContact OD1-NH2 3.31Å; D5-R289 IonicContact OD1-CZ 2.61Å; D5-R289 IonicContact OD1-NH1 3.54Å; D5-R289 IonicContact OD1-NH2 2.91Å; D5-R289 PolarHBondContact OD1-NH2 3.21Å; D5-R289 IonicContact OD2-NH1 2.72Å
6E72.1Confident74Confident60 Ų6051.8 Ų51.828%0.2826%0.256SS..Hα-helixtrans-62.5-36.4176.8-74.9162-133.100113.7T3 F4 E9 E10 K317T3-E6 PolarHBondContact N-OE1 3.49Å; T3-E6 WeakPolarHBondContact O-CB 3.46Å; T3-E6 PolarHBondContact O-N 2.94Å; T3-E6 VanDerWaalsContact OG1-CD 3.23Å; T3-E6 VanDerWaalsContact OG1-CG 3.22Å; T3-E6 WeakPolarHBondContact OG1-CG 3.4Å; T3-E6 PolarHBondContact OG1-N 3.43Å; T3-E6 PolarHBondContact OG1-OE1 3.32Å; F4-E6 VanDerWaalsContact C-N 3.33Å; F4-E6 PolarHBondContact O-N 2.89Å; E6-E9 WeakPolarHBondContact O-CB 3.34Å; E6-E9 PolarHBondContact O-N 3.34Å; E6-E10 PolarHBondContact O-N 3.45Å; E6-E10 VanDerWaalsContact O-N 3.1Å; E6-K317 IonicContact OE2-NZ 2.69Å; E6-K317 PolarHBondContact OE2-NZ 3.45Å
7I75.2Confident74.8Confident1 Ų149.2 Ų49.21%0.00524%0.243CC..Hα-helixtrans-75.3-35.5178.6-68.8179.3000110.9T3 F4 D5 E9 E10 A11 I304 L315 K317 I319 L322T3-I7 PolarHBondContact O-N 2.92Å; F4-I7 PolarHBondContact O-N 3.42Å; D5-I7 VanDerWaalsContact C-N 3.34Å; D5-I7 PolarHBondContact O-N 3.28Å; I7-E9 PolarHBondContact O-N 3.46Å; I7-E10 PolarHBondContact O-N 3.26Å; I7-A11 WeakPolarHBondContact O-CB 3.37Å; I7-A11 PolarHBondContact O-N 3.1Å; I7-I304 HydrophobicContact CG2-CG2 3.99Å; I7-L315 HydrophobicContact CG2-CD2 4.46Å; I7-K317 HydrophobicContact CD1-CB 4.2Å; I7-K317 HydrophobicContact CG1-CB 4.05Å; I7-K317 HydrophobicContact CG1-CD 4.16Å; I7-I319 HydrophobicContact CD1-CG1 4.42Å; I7-I319 HydrophobicContact CG2-CG1 4.45Å; I7-L322 HydrophobicContact CD1-CD1 3.43Å; I7-L322 VanDerWaalsContact CD1-CD1 3.43Å; I7-L322 HydrophobicContact CD1-CD2 3.52Å; I7-L322 HydrophobicContact CD1-CG 3.7Å
8L77.9Confident75.7Confident4 Ų446.6 Ų46.62%0.02123%0.231CC..Hα-helixtrans-64-34.4171.9-168.466.3000110.9F4 D5 A11 G12 V230F4-L8 HydrophobicContact CE1-CB 4.24Å; F4-L8 HydrophobicContact CE1-CD2 4.13Å; F4-L8 PolarHBondContact O-N 3.25Å; D5-L8 PolarHBondContact O-N 3.46Å; L8-A11 PolarHBondContact O-N 3.47Å; L8-G12 CarbonylContact O-C 3.53Å; L8-G12 PolarHBondContact O-N 3.1Å; L8-V230 VanDerWaalsContact CD2-C 3.49Å; L8-V230 WeakPolarHBondContact CD2-O 3.31Å
9E78.3Confident76.5Confident88 Ų8850.1 Ų50.141%0.41124%0.244SC..Hα-helixtrans-64.8-42173.2-71.7179.2175.600112.5D5 E6 I7 G12 N13D5-E9 WeakPolarHBondContact O-CG 3.25Å; D5-E9 PolarHBondContact O-N 3.06Å; E6-E9 WeakPolarHBondContact O-CB 3.34Å; E6-E9 PolarHBondContact O-N 3.34Å; I7-E9 PolarHBondContact O-N 3.46Å; E9-G12 WeakPolarHBondContact O-CA 3.31Å; E9-G12 PolarHBondContact O-N 2.86Å; E9-G12 VanDerWaalsContact O-N 3.1Å; E9-N13 WeakPolarHBondContact CA-OD1 3.42Å; E9-N13 WeakPolarHBondContact CB-OD1 3.49Å; E9-N13 WeakPolarHBondContact CG-OD1 3.48Å; E9-N13 PolarHBondContact O-OD1 3.49Å
10E78.3Confident77.3Confident34 Ų3453.5 Ų53.516%0.15926%0.255CS..Hα-helixtrans-63.5-41.3174.1-72.3-179.1-172.200112.6E6 I7 G12 K313 L315 Y316 K317E6-E10 PolarHBondContact O-N 3.45Å; E6-E10 VanDerWaalsContact O-N 3.1Å; I7-E10 PolarHBondContact O-N 3.26Å; E10-G12 PolarHBondContact O-N 2.69Å; E10-K313 WeakPolarHBondContact O-CB 3.32Å; E10-L315 HydrophobicContact CB-CD2 4.3Å; E10-Y316 HydrophobicContact CB-CE2 4.36Å; E10-Y316 VanDerWaalsContact CD-CD2 3.45Å; E10-Y316 HydrophobicContact CG-CD2 4Å; E10-Y316 HydrophobicContact CG-CE2 3.98Å; E10-Y316 WeakPolarHBondContact OE2-CD2 2.97Å; E10-Y316 PolarHBondContact OE2-N 3.13Å; E10-K317 WeakPolarHBondContact OE1-CD 3.23Å; E10-K317 WeakPolarHBondContact OE1-CE 3.47Å; E10-K317 WeakPolarHBondContact OE1-CG 3.23Å; E10-K317 IonicContact OE1-NZ 3.6Å; E10-K317 PolarHBondContact OE2-N 3.26Å
11A76.3Confident78Confident0 Ų051.2 Ų51.20%024%0.244CC..Hα-helixtrans-66.7-18.5174.700000112.9I7 L8 I304 I307 A308 N311 L315I7-A11 WeakPolarHBondContact O-CB 3.37Å; I7-A11 PolarHBondContact O-N 3.1Å; L8-A11 PolarHBondContact O-N 3.47Å; A11-I304 HydrophobicContact CB-CG2 4.44Å; A11-I307 HydrophobicContact CB-CG2 4.36Å; A11-A308 HydrophobicContact CB-CB 4.29Å; A11-N311 WeakPolarHBondContact O-CB 3.05Å; A11-N311 PolarHBondContact O-ND2 2.77Å; A11-L315 HydrophobicContact CB-CD2 4.04Å
12G79.8Confident80.2Confident11 Ų1143 Ų4311%0.11320%0.203CC..  trans112.7124.2-179.100000112.2L8 E9 E10 F14 Q18L8-G12 CarbonylContact O-C 3.53Å; L8-G12 PolarHBondContact O-N 3.1Å; E9-G12 WeakPolarHBondContact O-CA 3.31Å; E9-G12 PolarHBondContact O-N 2.86Å; E9-G12 VanDerWaalsContact O-N 3.1Å; E10-G12 PolarHBondContact O-N 2.69Å; G12-F14 VanDerWaalsContact C-N 3.34Å; G12-F14 PolarHBondContact O-N 3.48Å; G12-Q18 PolarHBondContact O-NE2 3.28Å; G12-Q18 PolarHBondContact O-OE1 2.93Å
13N76.4Confident81.9Confident35 Ų3543.3 Ų43.319%0.18721%0.209CC..THydrogen-bonded Turntrans-59.5-39.4-176.4-6112.9000113.3E9 G231 E233 Y234E9-N13 WeakPolarHBondContact CA-OD1 3.42Å; E9-N13 WeakPolarHBondContact CB-OD1 3.49Å; E9-N13 WeakPolarHBondContact CG-OD1 3.48Å; E9-N13 PolarHBondContact O-OD1 3.49Å; N13-G231 PolarHBondContact O-N 3.04Å; N13-E233 PolarHBondContact ND2-OE2 2.93Å; N13-Y234 HydrophobicContact CB-CD2 3.73Å; N13-Y234 HydrophobicContact CB-CE2 3.57Å
14F82.7Confident83.1Confident30 Ų3042.8 Ų42.813%0.13220%0.204CC..THydrogen-bonded Turntrans-156.360.6179.8-163.4-123.2000111.6G12 Q18 K19 F22 V230 Y234 M237 V238G12-F14 VanDerWaalsContact C-N 3.34Å; G12-F14 PolarHBondContact O-N 3.48Å; F14-Q18 VanDerWaalsContact CA-OE1 3.24Å; F14-Q18 HydrophobicContact CD2-CB 4.12Å; F14-Q18 HydrophobicContact CE2-CB 4.48Å; F14-K19 HydrophobicContact CD1-CD 4.25Å; F14-K19 HydrophobicContact CD1-CG 3.77Å; F14-K19 HydrophobicContact CE1-CD 4.16Å; F14-K19 HydrophobicContact CE1-CG 3.45Å; F14-K19 VanDerWaalsContact CE1-CG 3.45Å; F14-K19 HydrophobicContact CE2-CG 4.25Å; F14-K19 HydrophobicContact CG-CG 4.3Å; F14-K19 HydrophobicContact CZ-CG 3.72Å; F14-K19 VanDerWaalsContact O-CE 3.23Å; F14-K19 WeakPolarHBondContact O-CE 3.43Å; F14-F22 HydrophobicContact CE2-CB 4.29Å; F14-F22 HydrophobicContact CE2-CG 4.39Å; F14-F22 HydrophobicContact CZ-CB 4.42Å; F14-F22 HydrophobicContact CZ-CD1 4.03Å; F14-F22 HydrophobicContact CZ-CG 4.26Å; F14-V230 HydrophobicContact CD2-CG1 3.88Å; F14-V230 HydrophobicContact CD2-CG2 3.92Å; F14-V230 HydrophobicContact CE2-CG1 4.48Å; F14-V230 HydrophobicContact CE2-CG2 4.02Å; F14-Y234 HydrophobicContact CB-CD1 4.05Å; F14-Y234 HydrophobicContact CB-CD2 3.88Å; F14-Y234 HydrophobicContact CB-CE1 4.28Å; F14-Y234 HydrophobicContact CB-CE2 4.15Å; F14-Y234 HydrophobicContact CB-CG 3.84Å; F14-Y234 HydrophobicContact CD1-CD1 4.28Å; F14-Y234 HydrophobicContact CG-CD1 4.3Å; F14-Y234 HydrophobicContact CG-CG 4.31Å; F14-M237 HydrophobicContact CD1-CE 4.05Å; F14-M237 HydrophobicContact CE1-CE 3.7Å; F14-M237 HydrophobicContact CZ-CE 4.23Å; F14-V238 HydrophobicContact CE2-CG2 3.88Å; F14-V238 HydrophobicContact CZ-CG2 4.13Å
15G85.9Confident84.1Confident20 Ų2041.4 Ų41.421%0.20620%0.198CC..  trans-75.9-172.7179.500000114.6C17 Q18 K19 N311G15-C17 PolarHBondContact O-N 3.42Å; G15-Q18 PolarHBondContact O-N 3.21Å; G15-K19 WeakPolarHBondContact O-CB 3.05Å; G15-K19 WeakPolarHBondContact O-CG 3.43Å; G15-K19 PolarHBondContact O-N 2.95Å; G15-N311 VanDerWaalsContact C-OD1 3.32Å; G15-N311 WeakPolarHBondContact CA-OD1 3.38Å
16R88.2Confident85Confident193 Ų19339.2 Ų39.273%0.72819%0.187SC*.Hα-helixtrans-62.6-40-174.1-171.8178-178.5176.60.3112.6K19 R20 N311R16-K19 PolarHBondContact O-N 2.87Å; R16-R20 PolarHBondContact O-N 3.41Å; R16-N311 PolarHBondContact N-OD1 3.26Å
17C88Confident86Confident7 Ų740 Ų405%0.04719%0.191CC..Hα-helixtrans-62.8-50.9179-170.70000111.2G15 K19 R20 I21 E310 N311G15-C17 PolarHBondContact O-N 3.42Å; C17-K19 PolarHBondContact O-N 3.32Å; C17-R20 PolarHBondContact O-N 2.68Å; C17-I21 WeakPolarHBondContact O-CG1 3.37Å; C17-I21 PolarHBondContact O-N 2.94Å; C17-E310 HydrophobicContact CB-CB 4.05Å; C17-E310 HydrophobicContact CB-CG 3.92Å; C17-E310 WeakPolarHBondContact CB-OE2 3.5Å; C17-E310 PolarHBondContact SG-OE2 3.06Å; C17-N311 PolarHBondContact N-OD1 3.18Å
18Q89.6Confident86.8Confident3 Ų340.5 Ų40.51%0.01419%0.194CC..Hα-helixtrans-61.6-42178.4-71.6150.5-40.900111.5G12 F14 G15 R20 I21 F22 L229G12-Q18 PolarHBondContact O-NE2 3.28Å; G12-Q18 PolarHBondContact O-OE1 2.93Å; F14-Q18 VanDerWaalsContact CA-OE1 3.24Å; F14-Q18 HydrophobicContact CD2-CB 4.12Å; F14-Q18 HydrophobicContact CE2-CB 4.48Å; G15-Q18 PolarHBondContact O-N 3.21Å; Q18-R20 VanDerWaalsContact C-N 3.35Å; Q18-R20 PolarHBondContact O-N 2.77Å; Q18-I21 PolarHBondContact O-N 2.99Å; Q18-F22 WeakPolarHBondContact O-CB 3.08Å; Q18-F22 PolarHBondContact O-N 3.05Å; Q18-L229 WeakPolarHBondContact CG-O 3.33Å; Q18-L229 PolarHBondContact NE2-O 3.43Å
19K91.1Very high87.4Confident113 Ų11340.3 Ų40.349%0.49119%0.193SC..Hα-helixtrans-59.9-41.5175.1-75.9175.5-179.9178.30112.6F14 G15 R16 C17 A23F14-K19 HydrophobicContact CD1-CD 4.25Å; F14-K19 HydrophobicContact CD1-CG 3.77Å; F14-K19 HydrophobicContact CE1-CD 4.16Å; F14-K19 HydrophobicContact CE1-CG 3.45Å; F14-K19 VanDerWaalsContact CE1-CG 3.45Å; F14-K19 HydrophobicContact CE2-CG 4.25Å; F14-K19 HydrophobicContact CG-CG 4.3Å; F14-K19 HydrophobicContact CZ-CG 3.72Å; F14-K19 VanDerWaalsContact O-CE 3.23Å; F14-K19 WeakPolarHBondContact O-CE 3.43Å; G15-K19 WeakPolarHBondContact O-CB 3.05Å; G15-K19 WeakPolarHBondContact O-CG 3.43Å; G15-K19 PolarHBondContact O-N 2.95Å; R16-K19 PolarHBondContact O-N 2.87Å; C17-K19 PolarHBondContact O-N 3.32Å; K19-A23 WeakPolarHBondContact O-CB 3.34Å; K19-A23 PolarHBondContact O-N 3.26Å
20R92.9Very high88.1Confident118 Ų11838 Ų3845%0.44518%0.183SC..Hα-helixtrans-64-49.6175.9-178-176.867.3-143-13.4111.2R16 C17 Q18 F22 A23 L24 E310R16-R20 PolarHBondContact O-N 3.41Å; C17-R20 PolarHBondContact O-N 2.68Å; Q18-R20 VanDerWaalsContact C-N 3.35Å; Q18-R20 PolarHBondContact O-N 2.77Å; R20-F22 VanDerWaalsContact C-N 3.31Å; R20-F22 PolarHBondContact O-N 3.11Å; R20-A23 PolarHBondContact O-N 2.88Å; R20-L24 HydrophobicContact CG-CD1 4.41Å; R20-L24 WeakPolarHBondContact O-CG 3.34Å; R20-L24 PolarHBondContact O-N 3.39Å; R20-E310 IonicContact CZ-OE1 2.73Å; R20-E310 IonicContact CZ-OE2 3.2Å; R20-E310 IonicContact NH1-OE1 2.78Å; R20-E310 PolarHBondContact NH1-OE1 3.15Å; R20-E310 IonicContact NH1-OE2 2.68Å; R20-E310 IonicContact NH2-OE1 3.23Å; R20-E310 PolarHBondContact NH2-OE1 2.95Å; R20-E310 IonicContact NH2-OE2 3.26Å; R20-E310 PolarHBondContact NH2-OE2 3.26Å
21I91.6Very high88.9Confident5 Ų536.9 Ų36.93%0.02618%0.179CC..Hα-helixtrans-61.6-44.1179.7-66163.3000110.3C17 Q18 L24 L25 L229 I284 P285C17-I21 WeakPolarHBondContact O-CG1 3.37Å; C17-I21 PolarHBondContact O-N 2.94Å; Q18-I21 PolarHBondContact O-N 2.99Å; I21-L24 PolarHBondContact O-N 2.99Å; I21-L25 HydrophobicContact CG2-CD1 3.75Å; I21-L25 HydrophobicContact CG2-CG 4.35Å; I21-L25 WeakPolarHBondContact O-CB 3.41Å; I21-L25 WeakPolarHBondContact O-CG 3.09Å; I21-L25 PolarHBondContact O-N 2.87Å; I21-L229 HydrophobicContact CD1-CD1 4.49Å; I21-L229 HydrophobicContact CG2-CD1 3.89Å; I21-I284 HydrophobicContact CG2-CG2 4.04Å; I21-P285 HydrophobicContact CD1-CG 3.73Å
22F92.3Very high89.7Confident18 Ų1838 Ų388%0.07918%0.184CC..Hα-helixtrans-58.2-48.8176176.3-107.5000111.9F14 Q18 R20 L24 L25 C26 I226 V238 L241F14-F22 HydrophobicContact CE2-CB 4.29Å; F14-F22 HydrophobicContact CE2-CG 4.39Å; F14-F22 HydrophobicContact CZ-CB 4.42Å; F14-F22 HydrophobicContact CZ-CD1 4.03Å; F14-F22 HydrophobicContact CZ-CG 4.26Å; Q18-F22 WeakPolarHBondContact O-CB 3.08Å; Q18-F22 PolarHBondContact O-N 3.05Å; R20-F22 VanDerWaalsContact C-N 3.31Å; R20-F22 PolarHBondContact O-N 3.11Å; F22-L24 VanDerWaalsContact C-N 3.34Å; F22-L24 PolarHBondContact O-N 3.27Å; F22-L25 PolarHBondContact O-N 3.5Å; F22-C26 WeakPolarHBondContact CE2-SG 3.39Å; F22-C26 WeakPolarHBondContact CZ-SG 3.35Å; F22-C26 WeakPolarHBondContact O-CB 3.34Å; F22-C26 PolarHBondContact O-N 3.28Å; F22-C26 PolarHBondContact O-SG 2.86Å; F22-I226 HydrophobicContact CD2-CD1 4.07Å; F22-I226 HydrophobicContact CD2-CG1 4.49Å; F22-I226 HydrophobicContact CD2-CG2 3.82Å; F22-I226 HydrophobicContact CE2-CD1 4.33Å; F22-I226 HydrophobicContact CE2-CG2 4.29Å; F22-V238 HydrophobicContact CD2-CG1 3.82Å; F22-V238 HydrophobicContact CD2-CG2 4.24Å; F22-V238 HydrophobicContact CE2-CB 4.1Å; F22-V238 HydrophobicContact CE2-CG1 3.55Å; F22-V238 HydrophobicContact CE2-CG2 4.14Å; F22-V238 HydrophobicContact CZ-CG1 4.45Å; F22-V238 HydrophobicContact CZ-CG2 4.46Å; F22-L241 HydrophobicContact CE1-CB 4.05Å; F22-L241 HydrophobicContact CE1-CD1 3.93Å; F22-L241 HydrophobicContact CZ-CB 3.52Å; F22-L241 HydrophobicContact CZ-CD1 4.1Å; F22-L241 HydrophobicContact CZ-CG 4.48Å
23A92.5Very high90.3Very high44 Ų4437.6 Ų37.636%0.36418%0.179SC..Hα-helixtrans-61-40.4178.700000112.6K19 R20K19-A23 WeakPolarHBondContact O-CB 3.34Å; K19-A23 PolarHBondContact O-N 3.26Å; R20-A23 PolarHBondContact O-N 2.88Å
24L92.9Very high91.1Very high40 Ų4036 Ų3621%0.20917%0.171CC..Hα-helixtrans-62.7-51174.8-71.3171.7000111R20 I21 F22 C26 M27 Y280 L283 I284R20-L24 HydrophobicContact CG-CD1 4.41Å; R20-L24 WeakPolarHBondContact O-CG 3.34Å; R20-L24 PolarHBondContact O-N 3.39Å; I21-L24 PolarHBondContact O-N 2.99Å; F22-L24 VanDerWaalsContact C-N 3.34Å; F22-L24 PolarHBondContact O-N 3.27Å; L24-C26 VanDerWaalsContact C-N 3.27Å; L24-C26 PolarHBondContact O-N 3.22Å; L24-M27 WeakPolarHBondContact O-CB 3.22Å; L24-M27 PolarHBondContact O-N 3.47Å; L24-M27 VanDerWaalsContact O-N 3.12Å; L24-Y280 HydrophobicContact CB-CE2 3.93Å; L24-Y280 HydrophobicContact CD2-CE1 4.26Å; L24-Y280 VanDerWaalsContact O-CE2 3.29Å; L24-Y280 WeakPolarHBondContact O-CE2 3.36Å; L24-Y280 PolarHBondContact O-OH 3.05Å; L24-Y280 VanDerWaalsContact O-OH 3.13Å; L24-L283 HydrophobicContact CD1-CB 3.98Å; L24-L283 HydrophobicContact CD1-CD1 4.28Å; L24-I284 HydrophobicContact CB-CD1 4.5Å
25L91.9Very high91.6Very high0 Ų034.5 Ų34.50%017%0.165CC..Hα-helixtrans-65.5-30.1-177.6-71.9175.2000113.2I21 F22 M27 V28 F181 V222 L225 I226 I284I21-L25 HydrophobicContact CG2-CD1 3.75Å; I21-L25 HydrophobicContact CG2-CG 4.35Å; I21-L25 WeakPolarHBondContact O-CB 3.41Å; I21-L25 WeakPolarHBondContact O-CG 3.09Å; I21-L25 PolarHBondContact O-N 2.87Å; F22-L25 PolarHBondContact O-N 3.5Å; L25-M27 VanDerWaalsContact C-N 3.26Å; L25-M27 PolarHBondContact O-N 3.42Å; L25-V28 WeakPolarHBondContact O-CB 3.13Å; L25-V28 WeakPolarHBondContact O-CG2 3.36Å; L25-V28 PolarHBondContact O-N 2.94Å; L25-F181 HydrophobicContact CD2-CZ 4.34Å; L25-V222 HydrophobicContact CB-CG1 3.86Å; L25-V222 HydrophobicContact CD2-CG1 4.31Å; L25-V222 HydrophobicContact CD2-CG2 4.15Å; L25-V222 HydrophobicContact CG-CG1 4.48Å; L25-L225 HydrophobicContact CD1-CD2 4.03Å; L25-L225 HydrophobicContact CD1-CG 4.35Å; L25-I226 HydrophobicContact CB-CD1 3.73Å; L25-I226 HydrophobicContact CB-CG1 4.03Å; L25-I226 HydrophobicContact CD1-CD1 4.12Å; L25-I226 HydrophobicContact CD1-CG1 3.44Å; L25-I226 VanDerWaalsContact CD1-CG1 3.44Å; L25-I226 HydrophobicContact CG-CG1 4.36Å; L25-I284 HydrophobicContact CD1-CD1 4.3Å; L25-I284 HydrophobicContact CD2-CD1 3.31Å; L25-I284 HydrophobicContact CG-CD1 3.62Å
26C91.7Very high91.9Very high0 Ų034.6 Ų34.60%016%0.159CC..Hα-helixtrans-63.6-29174.3-73.80000113.6F22 L24 V28 S29 L242 F245F22-C26 WeakPolarHBondContact CE2-SG 3.39Å; F22-C26 WeakPolarHBondContact CZ-SG 3.35Å; F22-C26 WeakPolarHBondContact O-CB 3.34Å; F22-C26 PolarHBondContact O-N 3.28Å; F22-C26 PolarHBondContact O-SG 2.86Å; L24-C26 VanDerWaalsContact C-N 3.27Å; L24-C26 PolarHBondContact O-N 3.22Å; C26-V28 PolarHBondContact O-N 3.32Å; C26-S29 WeakPolarHBondContact O-CB 3.49Å; C26-S29 PolarHBondContact O-N 3.29Å; C26-S29 VanDerWaalsContact O-N 3.07Å; C26-L242 HydrophobicContact CB-CD1 4.49Å; C26-F245 HydrophobicContact CB-CB 4.29Å; C26-F245 HydrophobicContact CB-CD1 3.82Å; C26-F245 HydrophobicContact CB-CD2 3.58Å; C26-F245 HydrophobicContact CB-CE1 3.96Å; C26-F245 HydrophobicContact CB-CE2 3.72Å; C26-F245 HydrophobicContact CB-CG 3.63Å; C26-F245 HydrophobicContact CB-CZ 3.91Å
27M92.6Very high92Very high77 Ų7725.5 Ų25.538%0.37913%0.125SC..THydrogen-bonded Turntrans-63.5-23.2177.8-64.3-63.5171.300112.4L24 L25 S29 L30 P31 F245 F277L24-M27 WeakPolarHBondContact O-CB 3.22Å; L24-M27 PolarHBondContact O-N 3.47Å; L24-M27 VanDerWaalsContact O-N 3.12Å; L25-M27 VanDerWaalsContact C-N 3.26Å; L25-M27 PolarHBondContact O-N 3.42Å; M27-S29 VanDerWaalsContact C-N 3.26Å; M27-S29 PolarHBondContact O-N 3.32Å; M27-L30 WeakPolarHBondContact O-CB 3.14Å; M27-L30 PolarHBondContact O-N 3.15Å; M27-L30 HydrophobicContact SD-CD1 3.72Å; M27-P31 VanDerWaalsContact O-CD 3.31Å; M27-P31 WeakPolarHBondContact O-CD 3.49Å; M27-F245 HydrophobicContact CE-CE1 3.97Å; M27-F245 HydrophobicContact SD-CE1 4.14Å; M27-F277 HydrophobicContact CB-CE1 4.18Å; M27-F277 HydrophobicContact CB-CZ 4.47Å; M27-F277 WeakPolarHBondContact O-CZ 3.36Å
28V91.8Very high92.2Very high10 Ų1025.2 Ų25.26%0.06112%0.123CC..THydrogen-bonded Turntrans-67.5-28.8176.5-175.30000111.8L25 C26 L30 P31 F181 V222 F277 Y280L25-V28 WeakPolarHBondContact O-CB 3.13Å; L25-V28 WeakPolarHBondContact O-CG2 3.36Å; L25-V28 PolarHBondContact O-N 2.94Å; C26-V28 PolarHBondContact O-N 3.32Å; V28-L30 PolarHBondContact O-N 2.99Å; V28-P31 WeakPolarHBondContact O-CD 3.43Å; V28-F181 HydrophobicContact CG1-CE2 4.08Å; V28-F181 HydrophobicContact CG2-CE2 3.86Å; V28-F181 HydrophobicContact CG2-CZ 3.74Å; V28-V222 HydrophobicContact CG1-CG2 4.44Å; V28-F277 HydrophobicContact CB-CD2 4.38Å; V28-F277 HydrophobicContact CB-CE2 4.17Å; V28-F277 HydrophobicContact CG1-CD2 4.22Å; V28-F277 HydrophobicContact CG1-CE2 4.21Å; V28-F277 HydrophobicContact CG2-CD1 4.27Å; V28-F277 HydrophobicContact CG2-CD2 3.94Å; V28-F277 HydrophobicContact CG2-CE1 4.39Å; V28-F277 HydrophobicContact CG2-CE2 4.07Å; V28-F277 HydrophobicContact CG2-CG 4.06Å; V28-F277 HydrophobicContact CG2-CZ 4.3Å; V28-Y280 HydrophobicContact CG2-CE2 4.27Å
29S91.3Very high92.3Very high1 Ų125.2 Ų25.21%0.00712%0.123CC..Hα-helixtrans-69.1-21.1176.9-62.60000113.1C26 M27 F32 L242C26-S29 WeakPolarHBondContact O-CB 3.49Å; C26-S29 PolarHBondContact O-N 3.29Å; C26-S29 VanDerWaalsContact O-N 3.07Å; M27-S29 VanDerWaalsContact C-N 3.26Å; M27-S29 PolarHBondContact O-N 3.32Å; S29-F32 WeakPolarHBondContact O-CB 3.43Å; S29-F32 PolarHBondContact O-N 3.44Å; S29-L242 VanDerWaalsContact OG-CD1 3.24Å; S29-L242 WeakPolarHBondContact OG-CD1 3.45Å; S29-L242 PolarHBondContact OG-O 2.8Å
30L93.3Very high92.2Very high38 Ų3820.1 Ų20.120%0.19910%0.101CC..Hα-helixtrans-62.4-61-179.9-60.8178.2000111.8M27 V28 F32 S33 F245 V248 I252M27-L30 WeakPolarHBondContact O-CB 3.14Å; M27-L30 PolarHBondContact O-N 3.15Å; M27-L30 HydrophobicContact SD-CD1 3.72Å; V28-L30 PolarHBondContact O-N 2.99Å; L30-F32 PolarHBondContact O-N 3.38Å; L30-S33 PolarHBondContact O-N 2.92Å; L30-S33 PolarHBondContact O-OG 2.81Å; L30-F245 HydrophobicContact CD2-CD1 4.11Å; L30-F245 WeakPolarHBondContact CD2-O 3.49Å; L30-F245 HydrophobicContact CG-CD1 4.49Å; L30-V248 HydrophobicContact CD2-CB 4.03Å; L30-V248 HydrophobicContact CD2-CG1 3.88Å; L30-I252 HydrophobicContact CD1-CD1 4.44Å; L30-I252 HydrophobicContact CD2-CD1 4.28Å
31P93.7Very high92.2Very high11 Ų1115.5 Ų15.57%0.0718%0.084CC..Hα-helixtrans-66.3-22.2179.526.3-34.7000113M27 V28 S33 G34 V35 P273 Y274 F277M27-P31 VanDerWaalsContact O-CD 3.31Å; M27-P31 WeakPolarHBondContact O-CD 3.49Å; V28-P31 WeakPolarHBondContact O-CD 3.43Å; P31-S33 PolarHBondContact O-N 3.41Å; P31-G34 PolarHBondContact O-N 3.47Å; P31-G34 VanDerWaalsContact O-N 3.08Å; P31-V35 WeakPolarHBondContact O-CG2 3.19Å; P31-V35 PolarHBondContact O-N 3.06Å; P31-V35 VanDerWaalsContact O-N 3.12Å; P31-P273 HydrophobicContact CB-CB 4.35Å; P31-P273 HydrophobicContact CG-CB 4.19Å; P31-Y274 HydrophobicContact CB-CE2 3.94Å; P31-Y274 HydrophobicContact CG-CE1 4.14Å; P31-Y274 HydrophobicContact CG-CE2 4.27Å; P31-F277 HydrophobicContact CG-CE2 3.71Å; P31-F277 HydrophobicContact CG-CZ 4.15Å
32F93.3Very high92.2Very high24 Ų2415.3 Ų15.311%0.1058%0.083CC..Hα-helixtrans-57.4-36.9175175.8-134.5000112.3S29 L30 V35 Y36 F161 V215 W219 F246 Y274S29-F32 WeakPolarHBondContact O-CB 3.43Å; S29-F32 PolarHBondContact O-N 3.44Å; L30-F32 PolarHBondContact O-N 3.38Å; F32-V35 PolarHBondContact O-N 3.32Å; F32-Y36 PolarHBondContact O-N 3.38Å; F32-F161 HydrophobicContact CE2-CE1 4.47Å; F32-F161 HydrophobicContact CE2-CE2 4.39Å; F32-F161 AromaticContact CE2-CZ 3.79Å; F32-F161 HydrophobicContact CE2-CZ 3.79Å; F32-F161 HydrophobicContact CZ-CZ 4.43Å; F32-V215 HydrophobicContact CD2-CG1 3.11Å; F32-V215 HydrophobicContact CE2-CG1 3.27Å; F32-V215 HydrophobicContact CG-CG1 4.25Å; F32-W219 AromaticContact CD1-CD1 3.72Å; F32-W219 HydrophobicContact CD1-CG 4.43Å; F32-W219 AromaticContact CE1-CD1 3.91Å; F32-W219 HydrophobicContact CE1-CG 4.31Å; F32-F246 HydrophobicContact CB-CD2 4.43Å; F32-F246 AromaticContact CD1-CD2 3.41Å; F32-F246 HydrophobicContact CD1-CD2 3.41Å; F32-F246 VanDerWaalsContact CD1-CD2 3.41Å; F32-F246 AromaticContact CD1-CE2 3.58Å; F32-F246 HydrophobicContact CD1-CE2 3.58Å; F32-F246 AromaticContact CE1-CD2 3.92Å; F32-F246 HydrophobicContact CE1-CD2 3.92Å; F32-F246 AromaticContact CE1-CE2 3.79Å; F32-F246 HydrophobicContact CE1-CE2 3.79Å; F32-F246 HydrophobicContact CG-CD2 4.14Å; F32-F246 HydrophobicContact CG-CE2 4.15Å; F32-Y274 PolarHBondContact N-OH 3.27Å
33S92.6Very high92Very high2 Ų214.9 Ų14.91%0.0148%0.084CC..Hα-helixtrans-57.7-49.117368.80000112L30 P31 V35 Y36 V37 G249 I250L30-S33 PolarHBondContact O-N 2.92Å; L30-S33 PolarHBondContact O-OG 2.81Å; P31-S33 PolarHBondContact O-N 3.41Å; S33-V35 VanDerWaalsContact C-N 3.26Å; S33-V35 PolarHBondContact O-N 3.2Å; S33-Y36 PolarHBondContact O-N 3.45Å; S33-Y36 VanDerWaalsContact O-N 3.09Å; S33-V37 WeakPolarHBondContact O-CG2 3.3Å; S33-V37 PolarHBondContact O-N 3.37Å; S33-G249 WeakPolarHBondContact OG-CA 3.08Å; S33-G249 PolarHBondContact OG-O 3.45Å; S33-I250 PolarHBondContact OG-N 2.83Å
34G92.4Very high91.7Very high1 Ų114.7 Ų14.71%0.018%0.075CC..Hα-helixtrans-55.9-40.7175.200000112.6P31 G38P31-G34 PolarHBondContact O-N 3.47Å; P31-G34 VanDerWaalsContact O-N 3.08Å; G34-G38 WeakPolarHBondContact O-CA 3.28Å; G34-G38 PolarHBondContact O-N 2.81Å
35V93.6Very high91.4Very high0 Ų016 Ų160%09%0.085CC..Hα-helixtrans-66.7-43.7176.2-175.40000112.1P31 F32 S33 L157 R208 F211 V215 Y274P31-V35 WeakPolarHBondContact O-CG2 3.19Å; P31-V35 PolarHBondContact O-N 3.06Å; P31-V35 VanDerWaalsContact O-N 3.12Å; F32-V35 PolarHBondContact O-N 3.32Å; S33-V35 VanDerWaalsContact C-N 3.26Å; S33-V35 PolarHBondContact O-N 3.2Å; V35-L157 HydrophobicContact CG1-CD1 4.03Å; V35-L157 HydrophobicContact CG1-CD2 4.46Å; V35-L157 WeakPolarHBondContact O-CD2 3.29Å; V35-R208 VanDerWaalsContact CG1-NH1 3.29Å; V35-R208 PolarHBondContact O-NH1 3.44Å; V35-R208 VanDerWaalsContact O-NH1 3.11Å; V35-R208 PolarHBondContact O-NH2 3.48Å; V35-F211 HydrophobicContact CB-CE1 4.13Å; V35-F211 HydrophobicContact CB-CZ 4.23Å; V35-F211 HydrophobicContact CG1-CD1 3.9Å; V35-F211 HydrophobicContact CG1-CE1 3.62Å; V35-F211 HydrophobicContact CG1-CG 4.45Å; V35-F211 HydrophobicContact CG1-CZ 4Å; V35-F211 HydrophobicContact CG2-CE1 3.5Å; V35-F211 HydrophobicContact CG2-CE2 4Å; V35-F211 HydrophobicContact CG2-CZ 3.2Å; V35-V215 HydrophobicContact CB-CG2 4.32Å; V35-V215 HydrophobicContact CG1-CB 4.45Å; V35-V215 HydrophobicContact CG1-CG1 4.38Å; V35-V215 HydrophobicContact CG1-CG2 3.89Å; V35-V215 HydrophobicContact CG2-CG2 4.08Å; V35-Y274 HydrophobicContact CG2-CE2 4.16Å
36Y91.9Very high91.1Very high22 Ų2216.3 Ų16.39%0.0869%0.087CC..Hα-helixtrans-77.5-44.9-173.3-172.7-118.5000112.9F32 S33 Q154 F161 F246 Y361 Q362 I365F32-Y36 PolarHBondContact O-N 3.38Å; S33-Y36 PolarHBondContact O-N 3.45Å; S33-Y36 VanDerWaalsContact O-N 3.09Å; Y36-Q154 PolarHBondContact O-NE2 3.2Å; Y36-F161 AromaticContact CD2-CE2 3.54Å; Y36-F161 HydrophobicContact CD2-CE2 3.54Å; Y36-F161 HydrophobicContact CD2-CZ 4.04Å; Y36-F161 AromaticContact CE2-CE2 3.82Å; Y36-F161 HydrophobicContact CE2-CE2 3.82Å; Y36-F246 AromaticContact CD1-CZ 3.92Å; Y36-F246 HydrophobicContact CD1-CZ 3.92Å; Y36-Y361 HydrophobicContact CE1-CD1 4.21Å; Y36-Y361 AromaticContact CE1-CE1 3.9Å; Y36-Y361 HydrophobicContact CE1-CE1 3.9Å; Y36-Q362 PolarHBondContact OH-OE1 2.94Å; Y36-I365 HydrophobicContact CE1-CD1 4.45Å
37V91.6Very high90.8Very high2 Ų221.4 Ų21.41%0.01211%0.111CC..Hα-helixtrans-110.6-4.1-172.1-59.90000114.1S33 I39 V40 I250 L253 I365 F379S33-V37 WeakPolarHBondContact O-CG2 3.3Å; S33-V37 PolarHBondContact O-N 3.37Å; V37-I39 PolarHBondContact O-N 3.44Å; V37-V40 PolarHBondContact O-N 2.95Å; V37-I250 HydrophobicContact CG2-CG1 4.24Å; V37-L253 HydrophobicContact CG2-CD2 3.5Å; V37-I365 HydrophobicContact CB-CG2 3.97Å; V37-I365 HydrophobicContact CG1-CD1 3.55Å; V37-I365 HydrophobicContact CG1-CG1 4.48Å; V37-I365 HydrophobicContact CG1-CG2 3.78Å; V37-F379 HydrophobicContact CB-CE2 4.46Å; V37-F379 HydrophobicContact CB-CZ 3.83Å; V37-F379 HydrophobicContact CG2-CE1 4.26Å; V37-F379 HydrophobicContact CG2-CZ 3.63Å
38G90.8Very high90.6Very high0 Ų018.4 Ų18.40%010%0.096CC..THydrogen-bonded Turntrans-60.2-18.5-178.800000115.3G34 V40 F41 Q42G34-G38 WeakPolarHBondContact O-CA 3.28Å; G34-G38 PolarHBondContact O-N 2.81Å; G38-V40 PolarHBondContact O-N 2.77Å; G38-V40 VanDerWaalsContact O-N 3.15Å; G38-F41 PolarHBondContact O-N 3.02Å; G38-Q42 WeakPolarHBondContact O-CG 3.33Å; G38-Q42 PolarHBondContact O-N 3.42Å
39I91.8Very high90.4Very high4 Ų418.6 Ų18.62%0.02110%0.095CC..Hα-helixtrans-53.3-34.3174.4-173.3174.5000112.6V37 F41 Q42 G43 Y153 Q154 M366V37-I39 PolarHBondContact O-N 3.44Å; I39-F41 PolarHBondContact O-N 3.26Å; I39-Q42 PolarHBondContact O-N 3.35Å; I39-G43 WeakPolarHBondContact O-CA 3.41Å; I39-G43 PolarHBondContact O-N 2.89Å; I39-Y153 HydrophobicContact CB-CD1 4.28Å; I39-Y153 HydrophobicContact CB-CE1 4.48Å; I39-Y153 HydrophobicContact CD1-CD1 3.96Å; I39-Y153 HydrophobicContact CG1-CD1 4.01Å; I39-Q154 HydrophobicContact CD1-CB 3.73Å; I39-M366 HydrophobicContact CG2-CG 4.42Å
40V90.8Very high90.2Very high5 Ų518.8 Ų18.83%0.0310%0.096CC..Hα-helixtrans-59.9-30.9-179.8175.30000111.9V37 G38 I365 V375 F379V37-V40 PolarHBondContact O-N 2.95Å; G38-V40 PolarHBondContact O-N 2.77Å; G38-V40 VanDerWaalsContact O-N 3.15Å; V40-I365 HydrophobicContact CG2-CG2 4.13Å; V40-V375 HydrophobicContact CG1-CG1 3.64Å; V40-F379 HydrophobicContact CB-CD2 4.42Å; V40-F379 HydrophobicContact CB-CE2 4.01Å; V40-F379 HydrophobicContact CG1-CD2 4.01Å; V40-F379 HydrophobicContact CG1-CE2 4.11Å; V40-F379 HydrophobicContact CG2-CE2 3.96Å
41F91.3Very high89.9Confident22 Ų2222.1 Ų22.110%0.09611%0.106CC..Hα-helixtrans-97.1-37.2177.5-58.8-70.7000112.5G38 I39 L253 T254 A257 L266 V375 Y376 F379G38-F41 PolarHBondContact O-N 3.02Å; I39-F41 PolarHBondContact O-N 3.26Å; F41-L253 HydrophobicContact CD2-CD1 4.33Å; F41-L253 HydrophobicContact CD2-CD2 4.37Å; F41-L253 HydrophobicContact CD2-CG 4.2Å; F41-L253 HydrophobicContact CE2-CD2 4.15Å; F41-L253 HydrophobicContact CE2-CG 3.98Å; F41-T254 HydrophobicContact CZ-CG2 4.36Å; F41-A257 HydrophobicContact CB-CB 3.98Å; F41-A257 HydrophobicContact CD1-CB 3.64Å; F41-A257 HydrophobicContact CD2-CB 3.82Å; F41-A257 HydrophobicContact CE1-CB 4.03Å; F41-A257 HydrophobicContact CE2-CB 4.2Å; F41-A257 HydrophobicContact CG-CB 3.52Å; F41-A257 HydrophobicContact CZ-CB 4.3Å; F41-L266 HydrophobicContact CB-CD2 3.83Å; F41-V375 HydrophobicContact CD1-CG1 4.44Å; F41-V375 HydrophobicContact CE1-CG1 4.01Å; F41-Y376 HydrophobicContact CD1-CD1 4.24Å; F41-Y376 AromaticContact CD1-CE1 3.85Å; F41-Y376 HydrophobicContact CD1-CE1 3.85Å; F41-Y376 AromaticContact CE1-CD1 3.61Å; F41-Y376 HydrophobicContact CE1-CD1 3.61Å; F41-Y376 AromaticContact CE1-CE1 3.7Å; F41-Y376 HydrophobicContact CE1-CE1 3.7Å; F41-Y376 HydrophobicContact CZ-CD1 4.45Å; F41-F379 AromaticContact CE2-CD1 3.88Å; F41-F379 HydrophobicContact CE2-CD1 3.88Å; F41-F379 HydrophobicContact CE2-CD2 4.39Å; F41-F379 AromaticContact CE2-CE1 3.75Å; F41-F379 HydrophobicContact CE2-CE1 3.75Å; F41-F379 HydrophobicContact CE2-CE2 4.32Å; F41-F379 HydrophobicContact CE2-CG 4.15Å; F41-F379 AromaticContact CE2-CZ 3.97Å; F41-F379 HydrophobicContact CE2-CZ 3.97Å; F41-F379 HydrophobicContact CZ-CB 4.04Å; F41-F379 AromaticContact CZ-CD1 3.81Å; F41-F379 HydrophobicContact CZ-CD1 3.81Å; F41-F379 HydrophobicContact CZ-CD2 4.29Å; F41-F379 HydrophobicContact CZ-CE1 4.17Å; F41-F379 AromaticContact CZ-CG 3.81Å; F41-F379 HydrophobicContact CZ-CG 3.81Å
42Q91.9Very high89.4Confident0 Ų022.5 Ų22.50%011%0.108CC..Hα-helixtrans-75.7-31.2-176.9-67.1172.9-35.500113.2G38 I39 S135 F136 Y153 W263 L266G38-Q42 WeakPolarHBondContact O-CG 3.33Å; G38-Q42 PolarHBondContact O-N 3.42Å; I39-Q42 PolarHBondContact O-N 3.35Å; Q42-S135 WeakPolarHBondContact O-CA 3.27Å; Q42-S135 VanDerWaalsContact O-CB 3.26Å; Q42-S135 WeakPolarHBondContact O-CB 3.48Å; Q42-F136 VanDerWaalsContact C-CD1 3.49Å; Q42-F136 HydrophobicContact CB-CD1 4.06Å; Q42-F136 HydrophobicContact CB-CE1 4.17Å; Q42-F136 WeakPolarHBondContact O-CD1 3.44Å; Q42-F136 PolarHBondContact O-N 3.07Å; Q42-Y153 PolarHBondContact OE1-OH 3.31Å; Q42-W263 HydrophobicContact CB-CB 4.27Å; Q42-W263 HydrophobicContact CG-CB 4.35Å; Q42-L266 HydrophobicContact CG-CD2 4.09Å
43G87.7Confident88.9Confident10 Ų1023.5 Ų23.510%0.10312%0.118CC..THydrogen-bonded Turntrans-113.124.7-171.400000114.3I39 T45I39-G43 WeakPolarHBondContact O-CA 3.41Å; I39-G43 PolarHBondContact O-N 2.89Å; G43-T45 PolarHBondContact O-N 3.18Å
44F86.7Confident88.3Confident40 Ų4025.9 Ų25.918%0.17513%0.132CC..  trans-61.6134175.7173-104.6000110.9P46 R133 S135F44-P46 HydrophobicContact CD1-CB 4.41Å; F44-P46 HydrophobicContact CE1-CB 3.82Å; F44-P46 VanDerWaalsContact O-CD 3.24Å; F44-P46 WeakPolarHBondContact O-CD 3.43Å; F44-R133 VanDerWaalsContact CE1-NH2 3.26Å; F44-R133 VanDerWaalsContact CZ-NH2 3.3Å; F44-S135 WeakPolarHBondContact O-CB 3.35Å; F44-S135 PolarHBondContact O-OG 3Å
45T86.6Confident87.7Confident68 Ų6826 Ų2642%0.41713%0.133SC..  trans-97.9101.7174.848.40000109.4G43 V137G43-T45 PolarHBondContact O-N 3.18Å; T45-V137 HydrophobicContact CG2-CB 4.46Å; T45-V137 HydrophobicContact CG2-CG1 3.82Å; T45-V137 HydrophobicContact CG2-CG2 4.33Å
46P86.3Confident87.1Confident5 Ų527.2 Ų27.23%0.03214%0.141CC..  trans-68.1166.4171.824.4-28.6000111.9F44 H48 Y128 D129 T138F44-P46 HydrophobicContact CD1-CB 4.41Å; F44-P46 HydrophobicContact CE1-CB 3.82Å; F44-P46 VanDerWaalsContact O-CD 3.24Å; F44-P46 WeakPolarHBondContact O-CD 3.43Å; P46-H48 PolarHBondContact O-N 3.07Å; P46-H48 PolarHBondContact O-ND1 3.31Å; P46-Y128 HydrophobicContact CG-CD1 3.96Å; P46-Y128 HydrophobicContact CG-CG 4.42Å; P46-D129 WeakPolarHBondContact CB-O 3.36Å; P46-T138 HydrophobicContact CG-CG2 3.31Å
47E85.8Confident86.7Confident108 Ų10832.3 Ų32.351%0.50517%0.166SC..  trans-59.2137.2166.2-63.9-163.8164.200110.1W49 D129E47-W49 HydrophobicContact CB-CH2 3.45Å; E47-W49 VanDerWaalsContact CB-CH2 3.45Å; E47-W49 HydrophobicContact CB-CZ2 3.91Å; E47-W49 HydrophobicContact CB-CZ3 4.14Å; E47-D129 PolarHBondContact O-N 2.97Å
48H88.1Confident86.1Confident13 Ų1333.5 Ų33.56%0.0617%0.172CC..EExtended strand (participates in β ladder)trans-143.9154.2-172.355.6-82000111.1P46 Q87 W126 E127 Y128 C144P46-H48 PolarHBondContact O-N 3.07Å; P46-H48 PolarHBondContact O-ND1 3.31Å; H48-Q87 WeakPolarHBondContact O-CA 3.41Å; H48-Q87 WeakPolarHBondContact O-CB 3Å; H48-Q87 WeakPolarHBondContact O-CG 3.42Å; H48-W126 AromaticContact CD2-CE3 3.77Å; H48-W126 AromaticContact CD2-CZ3 3.83Å; H48-E127 VanDerWaalsContact CA-O 3.3Å; H48-E127 WeakPolarHBondContact CA-O 3.37Å; H48-Y128 HydrophobicContact CB-CD1 3.5Å; H48-Y128 HydrophobicContact CB-CE1 3.65Å; H48-Y128 HydrophobicContact CB-CG 4.47Å; H48-C144 PolarHBondContact NE2-SG 3.49Å; H48-C144 VanDerWaalsContact NE2-SG 3.43Å
49W87.4Confident85.6Confident14 Ų1436.5 Ų36.55%0.05318%0.183CC..EExtended strand (participates in β ladder)trans-141.2160.3178.3-57.3-83.3000110.3E47 R51 R70 V74 W126 E127 D129E47-W49 HydrophobicContact CB-CH2 3.45Å; E47-W49 VanDerWaalsContact CB-CH2 3.45Å; E47-W49 HydrophobicContact CB-CZ2 3.91Å; E47-W49 HydrophobicContact CB-CZ3 4.14Å; W49-R51 PolarHBondContact O-N 3Å; W49-R70 HydrophobicContact CD2-CG 4.43Å; W49-R70 VanDerWaalsContact CD2-NE 3.35Å; W49-R70 HydrophobicContact CG-CG 4.34Å; W49-V74 HydrophobicContact CB-CG2 4.19Å; W49-V74 HydrophobicContact CG-CG2 4.45Å; W49-W126 CarbonylContact O-C 3.6Å; W49-W126 WeakPolarHBondContact O-CA 3.42Å; W49-E127 PolarHBondContact N-O 3.28Å; W49-E127 PolarHBondContact O-N 3.31Å; W49-D129 HydrophobicContact CH2-CB 4.14Å; W49-D129 HydrophobicContact CZ3-CB 3.96Å
50C87.4Confident85.2Confident5 Ų543.8 Ų43.83%0.03422%0.217CC..EExtended strand (participates in β ladder)trans-61.4132.4172.9-55.90000110.6E89 Q90 C122C50-E89 VanDerWaalsContact SG-C 3.5Å; C50-Q90 HydrophobicContact CB-CB 3.8Å; C50-Q90 HydrophobicContact CB-CG 4.06Å; C50-Q90 VanDerWaalsContact CB-OE1 3.26Å; C50-Q90 VanDerWaalsContact SG-CB 3.51Å; C50-C122 WeakPolarHBondContact CA-SG 3.21Å; C50-C122 HydrophobicContact CB-CB 3.62Å; C50-C122 WeakPolarHBondContact CB-SG 3.38Å; C50-C122 VanDerWaalsContact SG-CA 3.54Å; C50-C122 WeakPolarHBondContact SG-CB 3.47Å; C50-C122 CovalentContact SG-SG 2Å; C50-C122 PolarHBondContact SG-SG 3.17Å
51R85.3Confident84.8Confident108 Ų10847.9 Ų47.941%0.40825%0.246SC..  trans-83.7131.5168.4-173.9173.862.8-163.8-3.4109.3W49 E124 G125 E127W49-R51 PolarHBondContact O-N 3Å; R51-E124 VanDerWaalsContact CZ-O 3.3Å; R51-E124 PolarHBondContact NE-O 3.14Å; R51-E124 PolarHBondContact NH2-O 3.03Å; R51-E124 WeakPolarHBondContact O-CB 3.46Å; R51-G125 PolarHBondContact N-O 3.33Å; R51-E127 HydrophobicContact CB-CG 4.03Å; R51-E127 HydrophobicContact CG-CG 4.02Å
52D84.4Confident84.3Confident20 Ų2048.4 Ų48.411%0.10725%0.252CS..  trans-116.9119170.1-174.2-62.5000108.5V54 V55 S56 T73 W95D52-V54 VanDerWaalsContact C-N 3.3Å; D52-V54 PolarHBondContact O-N 3.45Å; D52-V54 PolarHBondContact OD1-N 3.07Å; D52-V55 HydrophobicContact CB-CB 4.21Å; D52-V55 HydrophobicContact CB-CG2 4.27Å; D52-V55 PolarHBondContact O-N 3.35Å; D52-V55 PolarHBondContact OD1-N 3.4Å; D52-V55 VanDerWaalsContact OD1-N 3.16Å; D52-S56 VanDerWaalsContact O-CB 3.22Å; D52-S56 WeakPolarHBondContact O-CB 3.4Å; D52-S56 PolarHBondContact O-N 3.36Å; D52-T73 HydrophobicContact CB-CG2 3.92Å; D52-W95 VanDerWaalsContact CG-NE1 3.26Å; D52-W95 PolarHBondContact OD1-NE1 3.29Å; D52-W95 VanDerWaalsContact OD1-NE1 3.16Å; D52-W95 PolarHBondContact OD2-NE1 2.92Å
53S82.5Confident83.7Confident44 Ų4451.3 Ų51.331%0.30828%0.282SS..Hα-helixtrans-64.1-33.5-173.359.40000113.2Q57 E124S53-Q57 WeakPolarHBondContact O-CB 3.4Å; S53-Q57 VanDerWaalsContact O-CG 3.22Å; S53-Q57 WeakPolarHBondContact O-CG 3.29Å; S53-Q57 PolarHBondContact O-N 2.98Å; S53-E124 WeakPolarHBondContact CB-OE2 3.35Å; S53-E124 PolarHBondContact N-OE2 3.12Å; S53-E124 PolarHBondContact OG-OE2 3.49Å
54V80Confident83.2Confident53 Ų5352.1 Ų52.132%0.32128%0.282SS..Hα-helixtrans-71.9-48.2-179.5-178.50000109.8D52 S56 Q57 I58 W95D52-V54 VanDerWaalsContact C-N 3.3Å; D52-V54 PolarHBondContact O-N 3.45Å; D52-V54 PolarHBondContact OD1-N 3.07Å; V54-S56 VanDerWaalsContact C-N 3.33Å; V54-S56 PolarHBondContact O-N 3.2Å; V54-Q57 PolarHBondContact O-N 3.33Å; V54-I58 HydrophobicContact CG1-CD1 4.05Å; V54-I58 WeakPolarHBondContact O-CG1 3.34Å; V54-I58 PolarHBondContact O-N 3.17Å; V54-W95 HydrophobicContact CB-CB 4.29Å; V54-W95 HydrophobicContact CB-CG 3.94Å; V54-W95 HydrophobicContact CG1-CB 3.77Å; V54-W95 HydrophobicContact CG1-CG 3.84Å; V54-W95 HydrophobicContact CG2-CB 4.39Å; V54-W95 HydrophobicContact CG2-CG 4.27Å
55V79.7Confident82.8Confident4 Ų455.6 Ų55.62%0.02430%0.303CS..Hα-helixtrans-66.9-36.9178.3-178.30000111.1D52 Q57 I58 R59 A69 T73 W95D52-V55 HydrophobicContact CB-CB 4.21Å; D52-V55 HydrophobicContact CB-CG2 4.27Å; D52-V55 PolarHBondContact O-N 3.35Å; D52-V55 PolarHBondContact OD1-N 3.4Å; D52-V55 VanDerWaalsContact OD1-N 3.16Å; V55-Q57 VanDerWaalsContact C-N 3.35Å; V55-Q57 PolarHBondContact O-N 3.41Å; V55-I58 PolarHBondContact O-N 3.27Å; V55-R59 WeakPolarHBondContact O-CB 3.2Å; V55-R59 PolarHBondContact O-N 3.07Å; V55-A69 HydrophobicContact CG1-CB 3.77Å; V55-T73 HydrophobicContact CB-CG2 3.99Å; V55-T73 HydrophobicContact CG1-CG2 4.06Å; V55-T73 HydrophobicContact CG2-CG2 3.66Å; V55-W95 HydrophobicContact CG2-CD2 4.18Å; V55-W95 HydrophobicContact CG2-CE3 4.32Å; V55-W95 HydrophobicContact CG2-CH2 3.54Å; V55-W95 HydrophobicContact CG2-CZ2 3.31Å; V55-W95 HydrophobicContact CG2-CZ3 4.02Å
56S81.6Confident82.3Confident25 Ų2554.8 Ų54.818%0.17530%0.296CS..Hα-helixtrans-63.2-38.5174.7178.70000112.4D52 V54 Q60D52-S56 VanDerWaalsContact O-CB 3.22Å; D52-S56 WeakPolarHBondContact O-CB 3.4Å; D52-S56 PolarHBondContact O-N 3.36Å; V54-S56 VanDerWaalsContact C-N 3.33Å; V54-S56 PolarHBondContact O-N 3.2Å; S56-Q60 WeakPolarHBondContact O-CG 3.3Å; S56-Q60 PolarHBondContact O-N 2.65Å; S56-Q60 VanDerWaalsContact O-N 3.13Å
57Q82.3Confident81.8Confident129 Ų12960.2 Ų60.260%0.60332%0.322SS*.Hα-helixtrans-69.2-45.5177.3-76.7173.316.100111.8S53 V54 V55 R59 Q60 S61S53-Q57 WeakPolarHBondContact O-CB 3.4Å; S53-Q57 VanDerWaalsContact O-CG 3.22Å; S53-Q57 WeakPolarHBondContact O-CG 3.29Å; S53-Q57 PolarHBondContact O-N 2.98Å; V54-Q57 PolarHBondContact O-N 3.33Å; V55-Q57 VanDerWaalsContact C-N 3.35Å; V55-Q57 PolarHBondContact O-N 3.41Å; Q57-R59 VanDerWaalsContact C-N 3.29Å; Q57-R59 PolarHBondContact O-N 3.13Å; Q57-Q60 PolarHBondContact O-N 3.33Å; Q57-S61 PolarHBondContact O-N 3.41Å; Q57-S61 PolarHBondContact O-OG 2.91Å
58I78.9Confident81.4Confident27 Ų2757.1 Ų57.114%0.13831%0.309CS..Hα-helixtrans-62.1-40.6176.5-67.2174.2000110.3V54 V55 Q60 S61 C62 W64 L100V54-I58 HydrophobicContact CG1-CD1 4.05Å; V54-I58 WeakPolarHBondContact O-CG1 3.34Å; V54-I58 PolarHBondContact O-N 3.17Å; V55-I58 PolarHBondContact O-N 3.27Å; I58-Q60 VanDerWaalsContact C-N 3.33Å; I58-Q60 PolarHBondContact O-N 3.19Å; I58-S61 WeakPolarHBondContact CA-OG 3.36Å; I58-S61 PolarHBondContact O-N 3.49Å; I58-S61 PolarHBondContact O-OG 3.38Å; I58-S61 VanDerWaalsContact O-OG 3.05Å; I58-C62 VanDerWaalsContact CG2-SG 3.57Å; I58-C62 WeakPolarHBondContact O-CB 3.48Å; I58-C62 PolarHBondContact O-N 3.35Å; I58-C62 PolarHBondContact O-SG 3.28Å; I58-W64 HydrophobicContact CG2-CD2 4.49Å; I58-W64 HydrophobicContact CG2-CE3 4.3Å; I58-W64 HydrophobicContact CG2-CH2 3.91Å; I58-W64 HydrophobicContact CG2-CZ2 4.1Å; I58-W64 HydrophobicContact CG2-CZ3 4.01Å; I58-L100 HydrophobicContact CD1-CB 3.87Å; I58-L100 HydrophobicContact CD1-CD2 3.78Å; I58-L100 HydrophobicContact CD1-CG 4.37Å; I58-L100 HydrophobicContact CG2-CD2 4.43Å
59R82.3Confident80.8Confident62 Ų6256.9 Ų56.923%0.23431%0.309CS..Hα-helixtrans-59.1-43.8174.9175.8178.8168.3-147.2-11.7112.2V55 Q57 G63 W64 L66 E127V55-R59 WeakPolarHBondContact O-CB 3.2Å; V55-R59 PolarHBondContact O-N 3.07Å; Q57-R59 VanDerWaalsContact C-N 3.29Å; Q57-R59 PolarHBondContact O-N 3.13Å; R59-G63 WeakPolarHBondContact O-CA 3.45Å; R59-G63 PolarHBondContact O-N 3.39Å; R59-W64 HydrophobicContact CB-CB 4.36Å; R59-W64 HydrophobicContact CG-CB 4.1Å; R59-W64 WeakPolarHBondContact CG-O 3.48Å; R59-W64 PolarHBondContact O-N 3.17Å; R59-L66 VanDerWaalsContact NH1-CD1 3.33Å; R59-L66 VanDerWaalsContact NH1-CG 3.29Å; R59-E127 IonicContact NH1-OE1 3.38Å; R59-E127 IonicContact NH1-OE2 3.25Å; R59-E127 PolarHBondContact NH1-OE2 2.78Å
60Q83Confident80.3Confident157 Ų15758.1 Ų58.173%0.73431%0.314SS*.Hα-helixtrans-68.7-36.2178.3-74.71781.200112.7S56 Q57 I58S56-Q60 WeakPolarHBondContact O-CG 3.3Å; S56-Q60 PolarHBondContact O-N 2.65Å; S56-Q60 VanDerWaalsContact O-N 3.13Å; Q57-Q60 PolarHBondContact O-N 3.33Å; I58-Q60 VanDerWaalsContact C-N 3.33Å; I58-Q60 PolarHBondContact O-N 3.19Å
61S82.3Confident79.8Confident91 Ų9161.4 Ų61.464%0.63633%0.327SS*.Hα-helixtrans-79.4-38.3-179.6630000113.3Q57 I58Q57-S61 PolarHBondContact O-N 3.41Å; Q57-S61 PolarHBondContact O-OG 2.91Å; I58-S61 WeakPolarHBondContact CA-OG 3.36Å; I58-S61 PolarHBondContact O-N 3.49Å; I58-S61 PolarHBondContact O-OG 3.38Å; I58-S61 VanDerWaalsContact O-OG 3.05Å
62C79.9Confident79.4Confident34 Ų3456.4 Ų56.423%0.2331%0.309CS..Hα-helixtrans-94.1-7.9-177.1-50.70000113.6I58 W64 C102I58-C62 VanDerWaalsContact CG2-SG 3.57Å; I58-C62 WeakPolarHBondContact O-CB 3.48Å; I58-C62 PolarHBondContact O-N 3.35Å; I58-C62 PolarHBondContact O-SG 3.28Å; C62-W64 HydrophobicContact CB-CG 4.28Å; C62-C102 HydrophobicContact CB-CB 3.63Å; C62-C102 WeakPolarHBondContact CB-SG 3.4Å; C62-C102 WeakPolarHBondContact SG-CA 3.29Å; C62-C102 WeakPolarHBondContact SG-CB 3.5Å; C62-C102 CovalentContact SG-SG 2.03Å; C62-C102 PolarHBondContact SG-SG 2.96Å
63G80.1Confident79Confident61 Ų6156 Ų5663%0.62931%0.307SS*.THydrogen-bonded Turntrans70.231.1179.900000114.5R59R59-G63 WeakPolarHBondContact O-CA 3.45Å; R59-G63 PolarHBondContact O-N 3.39Å
64W76.8Confident79Confident26 Ų2654 Ų5410%0.09829%0.293CS..  trans-69.6149.1-178.4-68.6-3.2000113I58 R59 C62 I72 L100 T101 C102 P105I58-W64 HydrophobicContact CG2-CD2 4.49Å; I58-W64 HydrophobicContact CG2-CE3 4.3Å; I58-W64 HydrophobicContact CG2-CH2 3.91Å; I58-W64 HydrophobicContact CG2-CZ2 4.1Å; I58-W64 HydrophobicContact CG2-CZ3 4.01Å; R59-W64 HydrophobicContact CB-CB 4.36Å; R59-W64 HydrophobicContact CG-CB 4.1Å; R59-W64 WeakPolarHBondContact CG-O 3.48Å; R59-W64 PolarHBondContact O-N 3.17Å; C62-W64 HydrophobicContact CB-CG 4.28Å; W64-I72 HydrophobicContact CE3-CD1 4.48Å; W64-I72 HydrophobicContact CH2-CD1 4.42Å; W64-I72 HydrophobicContact CZ3-CD1 3.77Å; W64-L100 HydrophobicContact CH2-CD2 3.71Å; W64-L100 HydrophobicContact CH2-CG 4.01Å; W64-L100 HydrophobicContact CZ3-CD2 3.76Å; W64-T101 WeakPolarHBondContact CZ2-O 3.47Å; W64-C102 PolarHBondContact NE1-O 3.3Å; W64-P105 HydrophobicContact CD2-CB 4.2Å; W64-P105 HydrophobicContact CE3-CB 4.25Å; W64-P105 HydrophobicContact CH2-CB 3.71Å; W64-P105 HydrophobicContact CZ2-CB 3.64Å; W64-P105 HydrophobicContact CZ2-CG 4.36Å; W64-P105 HydrophobicContact CZ3-CB 4.02Å
65N78.6Confident79.1Confident114 Ų11451.4 Ų51.461%0.6128%0.277SS*.  trans-71.8149.2171.2-78.5-17.6000110.6M67 D68 A69N65-M67 PolarHBondContact O-N 3.21Å; N65-D68 PolarHBondContact O-N 3.33Å; N65-A69 PolarHBondContact O-N 3.19Å
66L76.6Confident79.1Confident51 Ų5155.5 Ų55.527%0.26730%0.298SS..Hα-helixtrans-61.4-32.9-178.4-159.9155.9000111.6R59 D68 A69 R70R59-L66 VanDerWaalsContact NH1-CD1 3.33Å; R59-L66 VanDerWaalsContact NH1-CG 3.29Å; L66-D68 VanDerWaalsContact C-N 3.33Å; L66-D68 PolarHBondContact O-N 3.39Å; L66-A69 PolarHBondContact O-N 3.14Å; L66-R70 HydrophobicContact CD2-CG 3.98Å; L66-R70 WeakPolarHBondContact O-CG 3.39Å; L66-R70 PolarHBondContact O-N 3.13Å
67M76.1Confident78.9Confident119 Ų11956.8 Ų56.859%0.58631%0.305SS*.Hα-helixtrans-59.9-38.9173.8-76.3-87.6-75.900113.4N65 R70 K71N65-M67 PolarHBondContact O-N 3.21Å; M67-R70 PolarHBondContact O-N 2.96Å; M67-K71 WeakPolarHBondContact O-CG 3.44Å; M67-K71 PolarHBondContact O-N 3.09Å; M67-K71 VanDerWaalsContact O-N 3.08Å
68D76.1Confident78.6Confident42 Ų4255.9 Ų55.923%0.22530%0.304CS..Hα-helixtrans-72.6-39.1-177.8-58.7-39.4000110.3N65 L66 R70 K71 I72N65-D68 PolarHBondContact O-N 3.33Å; L66-D68 VanDerWaalsContact C-N 3.33Å; L66-D68 PolarHBondContact O-N 3.39Å; D68-R70 PolarHBondContact O-N 3.08Å; D68-K71 PolarHBondContact O-N 3.16Å; D68-K71 IonicContact OD1-NZ 3.57Å; D68-I72 WeakPolarHBondContact O-CD1 3.37Å; D68-I72 VanDerWaalsContact O-CG1 3.25Å; D68-I72 WeakPolarHBondContact O-CG1 3.33Å; D68-I72 PolarHBondContact O-N 3.28Å
69A75.6Confident78.1Confident9 Ų958.3 Ų58.37%0.07432%0.321CS..Hα-helixtrans-59.9-45.517100000112.1V55 N65 L66 K71 I72 T73V55-A69 HydrophobicContact CG1-CB 3.77Å; N65-A69 PolarHBondContact O-N 3.19Å; L66-A69 PolarHBondContact O-N 3.14Å; A69-K71 PolarHBondContact O-N 3.14Å; A69-I72 PolarHBondContact O-N 3.48Å; A69-I72 VanDerWaalsContact O-N 3.13Å; A69-T73 PolarHBondContact O-N 3.37Å; A69-T73 VanDerWaalsContact O-N 3.11Å; A69-T73 PolarHBondContact O-OG1 3.05Å; A69-T73 VanDerWaalsContact O-OG1 3.1Å
70R77.6Confident77.2Confident39 Ų3961.4 Ų61.415%0.14735%0.352CS..Hα-helixtrans-59.4-42.6178.3-74.2176.6-174.5163.39.7112.6W49 L66 M67 D68 I72 V74W49-R70 HydrophobicContact CD2-CG 4.43Å; W49-R70 VanDerWaalsContact CD2-NE 3.35Å; W49-R70 HydrophobicContact CG-CG 4.34Å; L66-R70 HydrophobicContact CD2-CG 3.98Å; L66-R70 WeakPolarHBondContact O-CG 3.39Å; L66-R70 PolarHBondContact O-N 3.13Å; M67-R70 PolarHBondContact O-N 2.96Å; D68-R70 PolarHBondContact O-N 3.08Å; R70-I72 PolarHBondContact O-N 3.13Å; R70-V74 VanDerWaalsContact O-CB 3.29Å; R70-V74 WeakPolarHBondContact O-CB 3.26Å; R70-V74 PolarHBondContact O-N 2.63Å
71K77.3Confident76.3Confident74 Ų7457 Ų5732%0.32235%0.349SS..Hα-helixtrans-58.2-30.6178.1-77.7174176.9173.90112.7M67 D68 A69 E106 R114M67-K71 WeakPolarHBondContact O-CG 3.44Å; M67-K71 PolarHBondContact O-N 3.09Å; M67-K71 VanDerWaalsContact O-N 3.08Å; D68-K71 PolarHBondContact O-N 3.16Å; D68-K71 IonicContact OD1-NZ 3.57Å; A69-K71 PolarHBondContact O-N 3.14Å; K71-E106 IonicContact NZ-OE1 3.56Å; K71-E106 PolarHBondContact NZ-OE1 2.77Å; K71-R114 VanDerWaalsContact O-CZ 3.22Å; K71-R114 PolarHBondContact O-NH1 3.11Å
72I76Confident75.8Confident4 Ų457.1 Ų57.12%0.02135%0.346CS..Hα-helixtrans-87.2-44.6-174.1-58.8166000110.3W64 D68 A69 R70 W95 P105 L109W64-I72 HydrophobicContact CE3-CD1 4.48Å; W64-I72 HydrophobicContact CH2-CD1 4.42Å; W64-I72 HydrophobicContact CZ3-CD1 3.77Å; D68-I72 WeakPolarHBondContact O-CD1 3.37Å; D68-I72 VanDerWaalsContact O-CG1 3.25Å; D68-I72 WeakPolarHBondContact O-CG1 3.33Å; D68-I72 PolarHBondContact O-N 3.28Å; A69-I72 PolarHBondContact O-N 3.48Å; A69-I72 VanDerWaalsContact O-N 3.13Å; R70-I72 PolarHBondContact O-N 3.13Å; I72-W95 HydrophobicContact CG2-CH2 3.45Å; I72-W95 VanDerWaalsContact CG2-CH2 3.45Å; I72-W95 HydrophobicContact CG2-CZ3 3.76Å; I72-P105 HydrophobicContact CD1-CB 4.32Å; I72-P105 VanDerWaalsContact CD1-O 3.31Å; I72-P105 WeakPolarHBondContact CD1-O 3.48Å; I72-L109 HydrophobicContact CG2-CD1 3.53Å
73T76.6Confident75.5Confident10 Ų1061.3 Ų61.36%0.06137%0.365CS..Hα-helixtrans-87.8-28.8-17354.90000113.9D52 V55 A69 Q90 Y91 W95D52-T73 HydrophobicContact CB-CG2 3.92Å; V55-T73 HydrophobicContact CB-CG2 3.99Å; V55-T73 HydrophobicContact CG1-CG2 4.06Å; V55-T73 HydrophobicContact CG2-CG2 3.66Å; A69-T73 PolarHBondContact O-N 3.37Å; A69-T73 VanDerWaalsContact O-N 3.11Å; A69-T73 PolarHBondContact O-OG1 3.05Å; A69-T73 VanDerWaalsContact O-OG1 3.1Å; T73-Q90 WeakPolarHBondContact O-CA 3.22Å; T73-Y91 PolarHBondContact O-N 3.11Å; T73-W95 HydrophobicContact CG2-CH2 4.38Å; T73-W95 HydrophobicContact CG2-CZ2 4.07Å
74V82.1Confident75.4Confident2 Ų261.8 Ų61.81%0.01236%0.356CS..SBendtrans-109.2125.3-166.4-173.30000112.5W49 R70 H85 S86W49-V74 HydrophobicContact CB-CG2 4.19Å; W49-V74 HydrophobicContact CG-CG2 4.45Å; R70-V74 VanDerWaalsContact O-CB 3.29Å; R70-V74 WeakPolarHBondContact O-CB 3.26Å; R70-V74 PolarHBondContact O-N 2.63Å; V74-H85 HydrophobicContact CB-CB 4.41Å; V74-H85 HydrophobicContact CG1-CB 3.76Å; V74-H85 PolarHBondContact O-ND1 2.68Å; V74-S86 WeakPolarHBondContact CG1-O 3.42Å
75P82.1Confident75.6Confident0 Ų063.1 Ų63.10%036%0.363CS..  trans-68150.5176.228.2-33.1000112.8H85 S86 E89 Y91 M119P75-H85 CarbonylContact O-C 3.6Å; P75-H85 WeakPolarHBondContact O-CA 2.95Å; P75-S86 PolarHBondContact O-N 3.08Å; P75-E89 VanDerWaalsContact CD-O 3.24Å; P75-E89 WeakPolarHBondContact CD-O 3.41Å; P75-E89 HydrophobicContact CG-CB 4.14Å; P75-Y91 VanDerWaalsContact CA-CE2 3.43Å; P75-Y91 VanDerWaalsContact CA-CZ 3.49Å; P75-Y91 WeakPolarHBondContact CA-OH 3.09Å; P75-Y91 HydrophobicContact CB-CE1 3.92Å; P75-Y91 HydrophobicContact CB-CE2 3.87Å; P75-M119 HydrophobicContact CB-CE 4.14Å
76L79.8Confident75.8Confident89 Ų8958.5 Ų58.547%0.46634%0.339SS..EExtended strand (participates in β ladder)trans-86.4121.1170.1-69.7165.7000109.2L83L76-L83 HydrophobicContact CB-CD2 4.12Å
77V77.8Confident76.2Confident52 Ų5259.6 Ų59.632%0.31534%0.343SS..EExtended strand (participates in β ladder)trans-110.9141.1176.4179.90000108.4T79 V84V77-T79 PolarHBondContact O-N 3.09Å; V77-V84 PolarHBondContact N-O 3.2Å; V77-V84 PolarHBondContact O-N 3.29Å; V77-V84 VanDerWaalsContact O-O 3.06Å
78N76.3Confident76.7Confident110 Ų11056.2 Ų56.259%0.58833%0.33SS*.EExtended strand (participates in β ladder)trans-80.5100175.3-174.2-2.2000109.3G81 V82N78-G81 WeakPolarHBondContact OD1-CA 3.36Å; N78-G81 PolarHBondContact OD1-N 2.66Å; N78-V82 PolarHBondContact OD1-N 3.22Å
79T67.7Low77.2Confident79 Ų7958 Ų5849%0.48534%0.338SS..EExtended strand (participates in β ladder)trans-103.3113.9174.3-53.70000107.9V77 G81 V82V77-T79 PolarHBondContact O-N 3.09Å; T79-G81 PolarHBondContact O-N 3.48Å; T79-G81 VanDerWaalsContact O-N 3.17Å; T79-V82 PolarHBondContact N-O 2.87Å; T79-V82 PolarHBondContact O-N 2.86Å; T79-V82 VanDerWaalsContact O-N 3.1Å
80S63.8Low77.7Confident126 Ų12658 Ų5888%0.88134%0.336SS*.THydrogen-bonded Turntrans58.429.6174.7-50.30000115.2
81G63.1Low78Confident65 Ų6557.3 Ų57.367%0.6733%0.334SS*.THydrogen-bonded Turntrans89.60.3179.500000114.6N78 T79N78-G81 WeakPolarHBondContact OD1-CA 3.36Å; N78-G81 PolarHBondContact OD1-N 2.66Å; T79-G81 PolarHBondContact O-N 3.48Å; T79-G81 VanDerWaalsContact O-N 3.17Å
82V72Confident78.2Confident94 Ų9457 Ų5757%0.5734%0.336SS*.EExtended strand (participates in β ladder)trans-114.7134.6174.9-176.70000109.1N78 T79 V84N78-V82 PolarHBondContact OD1-N 3.22Å; T79-V82 PolarHBondContact N-O 2.87Å; T79-V82 PolarHBondContact O-N 2.86Å; T79-V82 VanDerWaalsContact O-N 3.1Å; V82-V84 HydrophobicContact CB-CG2 4.29Å; V82-V84 HydrophobicContact CG1-CG2 3.95Å; V82-V84 PolarHBondContact O-N 3.25Å
83L73.8Confident78.3Confident121 Ų12158.1 Ų58.163%0.63434%0.341SS*.EExtended strand (participates in β ladder)trans-75.2110.4172.8-76.5157.3000108.7L76L76-L83 HydrophobicContact CB-CD2 4.12Å
84V78.7Confident78.2Confident72 Ų7262.4 Ų62.444%0.43636%0.364SS..EExtended strand (participates in β ladder)trans-123147.5178.6-173.20000108.5V77 V82 S86V77-V84 PolarHBondContact N-O 3.2Å; V77-V84 PolarHBondContact O-N 3.29Å; V77-V84 VanDerWaalsContact O-O 3.06Å; V82-V84 HydrophobicContact CB-CG2 4.29Å; V82-V84 HydrophobicContact CG1-CG2 3.95Å; V82-V84 PolarHBondContact O-N 3.25Å; V84-S86 PolarHBondContact O-N 2.71Å
85H81.2Confident77.8Confident53 Ų5363.5 Ų63.525%0.24537%0.368CS..EExtended strand (participates in β ladder)trans-61.7133.1173.8-74.4-73000110.7V74 P75V74-H85 HydrophobicContact CB-CB 4.41Å; V74-H85 HydrophobicContact CG1-CB 3.76Å; V74-H85 PolarHBondContact O-ND1 2.68Å; P75-H85 CarbonylContact O-C 3.6Å; P75-H85 WeakPolarHBondContact O-CA 2.95Å
86S82.3Confident77.3Confident17 Ų1770.6 Ų70.612%0.11941%0.406CS..  trans-61.1134.2175.3-168.10000110.6V74 P75 V84 E89V74-S86 WeakPolarHBondContact CG1-O 3.42Å; P75-S86 PolarHBondContact O-N 3.08Å; V84-S86 PolarHBondContact O-N 2.71Å; S86-E89 PolarHBondContact OG-N 3.29Å
87Q84.2Confident76.7Confident75 Ų7573 Ų7335%0.3542%0.419SS..SBendtrans-83.7-22.4177.1-68.3-176.6-20.300112.4H48 W126H48-Q87 WeakPolarHBondContact O-CA 3.41Å; H48-Q87 WeakPolarHBondContact O-CB 3Å; H48-Q87 WeakPolarHBondContact O-CG 3.42Å; Q87-W126 WeakPolarHBondContact O-CZ3 3.41Å
88C86.7Confident76.1Confident47 Ų4772.1 Ų72.132%0.31841%0.414SS..SBendtrans-117.2-7-167.1-64.10000115.4C144C88-C144 WeakPolarHBondContact CA-SG 3.43Å; C88-C144 HydrophobicContact CB-CB 3.7Å; C88-C144 WeakPolarHBondContact CB-SG 3.15Å; C88-C144 WeakPolarHBondContact SG-CB 3.29Å; C88-C144 CovalentContact SG-SG 2.02Å; C88-C144 PolarHBondContact SG-SG 2.49Å
89E86.4Confident75.5Confident81 Ų8169 Ų6938%0.37941%0.408SS..EExtended strand (participates in β ladder)trans-125.2149.3-175.6-60.9179.2149.400110.3C50 P75 S86C50-E89 VanDerWaalsContact SG-C 3.5Å; P75-E89 VanDerWaalsContact CD-O 3.24Å; P75-E89 WeakPolarHBondContact CD-O 3.41Å; P75-E89 HydrophobicContact CG-CB 4.14Å; S86-E89 PolarHBondContact OG-N 3.29Å
90Q86.3Confident75.6Confident9 Ų966.7 Ų66.74%0.04239%0.392CS..EExtended strand (participates in β ladder)trans-132.4158.9173.654.9179.74.800111C50 T73 T120C50-Q90 HydrophobicContact CB-CB 3.8Å; C50-Q90 HydrophobicContact CB-CG 4.06Å; C50-Q90 VanDerWaalsContact CB-OE1 3.26Å; C50-Q90 VanDerWaalsContact SG-CB 3.51Å; T73-Q90 WeakPolarHBondContact O-CA 3.22Å; Q90-T120 PolarHBondContact N-O 3.36Å; Q90-T120 PolarHBondContact O-N 3.36Å
91Y83.4Confident75.8Confident24 Ų2464.2 Ų64.29%0.09437%0.372CS..EExtended strand (participates in β ladder)trans-70.3130.6167.2-66.2-67.3000110.3T73 P75 L93 R114 A117 M119T73-Y91 PolarHBondContact O-N 3.11Å; P75-Y91 VanDerWaalsContact CA-CE2 3.43Å; P75-Y91 VanDerWaalsContact CA-CZ 3.49Å; P75-Y91 WeakPolarHBondContact CA-OH 3.09Å; P75-Y91 HydrophobicContact CB-CE1 3.92Å; P75-Y91 HydrophobicContact CB-CE2 3.87Å; Y91-L93 PolarHBondContact O-N 3.31Å; Y91-L93 VanDerWaalsContact O-N 3.1Å; Y91-R114 HydrophobicContact CD1-CG 4.4Å; Y91-R114 HydrophobicContact CD2-CG 4.07Å; Y91-R114 HydrophobicContact CE1-CG 3.85Å; Y91-R114 VanDerWaalsContact CE1-O 3.3Å; Y91-R114 WeakPolarHBondContact CE1-O 3.32Å; Y91-R114 HydrophobicContact CE2-CG 3.47Å; Y91-R114 VanDerWaalsContact CE2-CG 3.47Å; Y91-R114 HydrophobicContact CG-CG 4.49Å; Y91-A117 HydrophobicContact CD1-CB 3.88Å; Y91-A117 HydrophobicContact CG-CB 4.48Å; Y91-M119 HydrophobicContact CE1-CE 4.35Å
92D82Confident76.2Confident68 Ų6864.2 Ų64.236%0.36436%0.361SS..  trans-8384.7172.7-156.817.5000108.4P118 T120 K123D92-P118 HydrophobicContact CB-CG 4.23Å; D92-P118 WeakPolarHBondContact CB-O 3.39Å; D92-P118 PolarHBondContact N-O 2.92Å; D92-T120 HydrophobicContact CB-CG2 3.82Å; D92-K123 IonicContact OD1-NZ 3.99Å; D92-K123 PolarHBondContact OD1-NZ 3.24Å; D92-K123 IonicContact OD2-NZ 3.72Å; D92-K123 PolarHBondContact OD2-NZ 3.22Å
93L77.5Confident75.9Confident27 Ų2766.7 Ų66.714%0.14137%0.371CS..  trans-104.1134.4-178.3-64.3172.8000110.3Y91 W95 L109 A117Y91-L93 PolarHBondContact O-N 3.31Å; Y91-L93 VanDerWaalsContact O-N 3.1Å; L93-W95 HydrophobicContact CB-CH2 4.32Å; L93-W95 HydrophobicContact CB-CZ2 4.1Å; L93-W95 HydrophobicContact CD1-CH2 3.64Å; L93-W95 HydrophobicContact CD1-CZ2 4.06Å; L93-W95 HydrophobicContact CD1-CZ3 4.21Å; L93-W95 PolarHBondContact O-N 3.35Å; L93-L109 HydrophobicContact CD1-CD1 4.41Å; L93-L109 HydrophobicContact CD1-CD2 4Å; L93-L109 HydrophobicContact CD2-CD2 4.18Å; L93-A117 HydrophobicContact CD2-CB 3.74Å
94D75.9Confident75.3Confident100 Ų10065.2 Ų65.254%0.53536%0.364SS..  trans-92.195.6174.5-159.5-8.1000109.4N96 N97D94-N96 PolarHBondContact O-N 3.24Å; D94-N96 VanDerWaalsContact O-N 3.14Å; D94-N97 PolarHBondContact O-N 3.38Å
95W73.9Confident74.3Confident25 Ų2563.4 Ų63.410%0.09535%0.354CS..Hα-helixtrans-62-22.9-170.6-60.9108.3000114.6D52 V54 V55 I72 T73 L93 N97 T98 G99 L100 L109D52-W95 VanDerWaalsContact CG-NE1 3.26Å; D52-W95 PolarHBondContact OD1-NE1 3.29Å; D52-W95 VanDerWaalsContact OD1-NE1 3.16Å; D52-W95 PolarHBondContact OD2-NE1 2.92Å; V54-W95 HydrophobicContact CB-CB 4.29Å; V54-W95 HydrophobicContact CB-CG 3.94Å; V54-W95 HydrophobicContact CG1-CB 3.77Å; V54-W95 HydrophobicContact CG1-CG 3.84Å; V54-W95 HydrophobicContact CG2-CB 4.39Å; V54-W95 HydrophobicContact CG2-CG 4.27Å; V55-W95 HydrophobicContact CG2-CD2 4.18Å; V55-W95 HydrophobicContact CG2-CE3 4.32Å; V55-W95 HydrophobicContact CG2-CH2 3.54Å; V55-W95 HydrophobicContact CG2-CZ2 3.31Å; V55-W95 HydrophobicContact CG2-CZ3 4.02Å; I72-W95 HydrophobicContact CG2-CH2 3.45Å; I72-W95 VanDerWaalsContact CG2-CH2 3.45Å; I72-W95 HydrophobicContact CG2-CZ3 3.76Å; T73-W95 HydrophobicContact CG2-CH2 4.38Å; T73-W95 HydrophobicContact CG2-CZ2 4.07Å; L93-W95 HydrophobicContact CB-CH2 4.32Å; L93-W95 HydrophobicContact CB-CZ2 4.1Å; L93-W95 HydrophobicContact CD1-CH2 3.64Å; L93-W95 HydrophobicContact CD1-CZ2 4.06Å; L93-W95 HydrophobicContact CD1-CZ3 4.21Å; L93-W95 PolarHBondContact O-N 3.35Å; W95-N97 PolarHBondContact O-N 3.45Å; W95-T98 WeakPolarHBondContact CA-OG1 3.06Å; W95-T98 PolarHBondContact O-N 3.12Å; W95-T98 PolarHBondContact O-OG1 3.01Å; W95-G99 PolarHBondContact O-N 3.25Å; W95-L100 HydrophobicContact CE3-CD1 4.21Å; W95-L100 HydrophobicContact CE3-CD2 4.29Å; W95-L100 HydrophobicContact CZ3-CD1 3.87Å; W95-L100 HydrophobicContact CZ3-CD2 4.14Å; W95-L109 HydrophobicContact CZ3-CD1 4.11Å
96N70.1Confident73.1Confident149 Ų14966.6 Ų66.680%0.79737%0.369SS*.Hα-helixtrans-63.8-28.4175.5-76.4-23.5000112.6D94D94-N96 PolarHBondContact O-N 3.24Å; D94-N96 VanDerWaalsContact O-N 3.14Å
97N67.2Low71.7Confident138 Ų13868.5 Ų68.574%0.73838%0.382SS*.Hα-helixtrans-92.2-17.8-179.8-67.7-34.9000112.9D94 W95D94-N97 PolarHBondContact O-N 3.38Å; W95-N97 PolarHBondContact O-N 3.45Å
98T66.5Low70.2Confident35 Ų3569.8 Ų69.822%0.21539%0.391CS..Hα-helixtrans-92.2-15.3-175.258.10000113.8W95 L100 L109W95-T98 WeakPolarHBondContact CA-OG1 3.06Å; W95-T98 PolarHBondContact O-N 3.12Å; W95-T98 PolarHBondContact O-OG1 3.01Å; T98-L100 VanDerWaalsContact C-N 3.32Å; T98-L100 PolarHBondContact O-N 3.37Å; T98-L109 HydrophobicContact CG2-CD2 4.47Å
99G63.3Low68.8Low45 Ų4568 Ų6846%0.46438%0.379SS..THydrogen-bonded Turntrans61.336.2169.800000114.3W95 T101W95-G99 PolarHBondContact O-N 3.25Å; G99-T101 PolarHBondContact O-N 3.13Å
100L69.2Low67.4Low29 Ų2967.9 Ų67.915%0.15238%0.383CS..  trans-58.4121.6-175.8-142.783.2000111.3I58 W64 W95 T98 L109I58-L100 HydrophobicContact CD1-CB 3.87Å; I58-L100 HydrophobicContact CD1-CD2 3.78Å; I58-L100 HydrophobicContact CD1-CG 4.37Å; I58-L100 HydrophobicContact CG2-CD2 4.43Å; W64-L100 HydrophobicContact CH2-CD2 3.71Å; W64-L100 HydrophobicContact CH2-CG 4.01Å; W64-L100 HydrophobicContact CZ3-CD2 3.76Å; W95-L100 HydrophobicContact CE3-CD1 4.21Å; W95-L100 HydrophobicContact CE3-CD2 4.29Å; W95-L100 HydrophobicContact CZ3-CD1 3.87Å; W95-L100 HydrophobicContact CZ3-CD2 4.14Å; T98-L100 VanDerWaalsContact C-N 3.32Å; T98-L100 PolarHBondContact O-N 3.37Å; L100-L109 HydrophobicContact CD1-CD1 4.17Å
101T68.4Low66.1Low75 Ų7573.4 Ų73.446%0.4641%0.413SS..  trans-122.5159.2-18054.20000111.6W64 G99 D103W64-T101 WeakPolarHBondContact CZ2-O 3.47Å; G99-T101 PolarHBondContact O-N 3.13Å; T101-D103 PolarHBondContact O-N 3.49Å
102C70.8Confident64.6Low64 Ų6474.9 Ų74.943%0.43243%0.431SS..THydrogen-bonded Turntrans-60.6-26.5-178.1-65.40000114.3C62 W64C62-C102 HydrophobicContact CB-CB 3.63Å; C62-C102 WeakPolarHBondContact CB-SG 3.4Å; C62-C102 WeakPolarHBondContact SG-CA 3.29Å; C62-C102 WeakPolarHBondContact SG-CB 3.5Å; C62-C102 CovalentContact SG-SG 2.03Å; C62-C102 PolarHBondContact SG-SG 2.96Å; W64-C102 PolarHBondContact NE1-O 3.3Å
103D66.3Low63.6Low147 Ų14777.7 Ų77.779%0.78644%0.441SS*.THydrogen-bonded Turntrans-82.9-15.7-167.2-66.3-36.2000113.9T101T101-D103 PolarHBondContact O-N 3.49Å
104N61.6Low63Low89 Ų8978.4 Ų78.448%0.47644%0.442SS..  trans-150.792.8177.3-102.6-17.4000113E106 S107N104-E106 PolarHBondContact O-N 2.96Å; N104-S107 WeakPolarHBondContact CB-OG 3.48Å; N104-S107 VanDerWaalsContact CG-OG 3.28Å; N104-S107 WeakPolarHBondContact ND2-CB 3.43Å; N104-S107 PolarHBondContact ND2-OG 3.36Å
105P56.8Low62.4Low35 Ų3578.1 Ų78.123%0.22745%0.448CS..SBendtrans-66.7-23.1175.422.4-30.2000113.8W64 I72W64-P105 HydrophobicContact CD2-CB 4.2Å; W64-P105 HydrophobicContact CE3-CB 4.25Å; W64-P105 HydrophobicContact CH2-CB 3.71Å; W64-P105 HydrophobicContact CZ2-CB 3.64Å; W64-P105 HydrophobicContact CZ2-CG 4.36Å; W64-P105 HydrophobicContact CZ3-CB 4.02Å; I72-P105 HydrophobicContact CD1-CB 4.32Å; I72-P105 VanDerWaalsContact CD1-O 3.31Å; I72-P105 WeakPolarHBondContact CD1-O 3.48Å
106E56.9Low62.1Low119 Ų11985.3 Ų85.356%0.55648%0.48SS*.SBendtrans-108.2-16.2-172.6-68.9-173.9158.700114.7K71 N104K71-E106 IonicContact NZ-OE1 3.56Å; K71-E106 PolarHBondContact NZ-OE1 2.77Å; N104-E106 PolarHBondContact O-N 2.96Å
107S52.8Low62.2Low57 Ų5779 Ų7940%0.39945%0.448SS..SBendtrans-90.8-18.4-161.381.10000117.8N104N104-S107 WeakPolarHBondContact CB-OG 3.48Å; N104-S107 VanDerWaalsContact CG-OG 3.28Å; N104-S107 WeakPolarHBondContact ND2-CB 3.43Å; N104-S107 PolarHBondContact ND2-OG 3.36Å
108D51.8Low62.8Low103 Ų10376.3 Ų76.355%0.55144%0.438SS*.SBendtrans-105.9-9.5-173.2-77.81000114.5T110D108-T110 PolarHBondContact O-N 2.69Å
109L58.3Low63.6Low10 Ų1079.7 Ų79.75%0.05245%0.453CS..SBendtrans-97.478.7167-83.5149.7000108.8I72 L93 W95 T98 L100 D111I72-L109 HydrophobicContact CG2-CD1 3.53Å; L93-L109 HydrophobicContact CD1-CD1 4.41Å; L93-L109 HydrophobicContact CD1-CD2 4Å; L93-L109 HydrophobicContact CD2-CD2 4.18Å; W95-L109 HydrophobicContact CZ3-CD1 4.11Å; T98-L109 HydrophobicContact CG2-CD2 4.47Å; L100-L109 HydrophobicContact CD1-CD1 4.17Å; L109-D111 PolarHBondContact O-N 2.83Å
110T56.8Low64.6Low77 Ų7779.1 Ų79.147%0.47244%0.44SS..  trans-49.6135169.9480000109.2D108 A112 H113 R114D108-T110 PolarHBondContact O-N 2.69Å; T110-A112 PolarHBondContact O-N 3.26Å; T110-H113 PolarHBondContact O-N 3.47Å; T110-H113 PolarHBondContact OG1-ND1 3.22Å; T110-R114 PolarHBondContact O-N 2.78Å
111D58Low65.4Low125 Ų12581 Ų8167%0.66846%0.456SS*.Hα-helixtrans-50-25.6178.6-70.9-42.5000112.4L109 R114 S115L109-D111 PolarHBondContact O-N 2.83Å; D111-R114 PolarHBondContact O-N 3.25Å; D111-S115 WeakPolarHBondContact O-CB 3.41Å; D111-S115 PolarHBondContact O-N 2.94Å; D111-S115 PolarHBondContact O-OG 3.49Å
112A52.5Low66.2Low56 Ų5678.5 Ų78.546%0.46344%0.441SS..Hα-helixtrans-63.5-40.8172.100000114.5T110 S115T110-A112 PolarHBondContact O-N 3.26Å; A112-S115 PolarHBondContact O-OG 2.89Å
113H62.2Low66.7Low126 Ų12681.4 Ų81.458%0.58345%0.447SS*.Hα-helixtrans-71.6-38.1173.7-72.5154.5000111.5T110 K116 A117T110-H113 PolarHBondContact O-N 3.47Å; T110-H113 PolarHBondContact OG1-ND1 3.22Å; H113-K116 PolarHBondContact O-N 3.19Å; H113-A117 PolarHBondContact O-N 2.91Å
114R64.8Low67.5Low43 Ų4378.7 Ų78.716%0.16243%0.429CS..Hα-helixtrans-64.5-40.6176.5-167.6-176.3-61.6177.54.9112.4K71 Y91 T110 D111 K116 A117K71-R114 VanDerWaalsContact O-CZ 3.22Å; K71-R114 PolarHBondContact O-NH1 3.11Å; Y91-R114 HydrophobicContact CD1-CG 4.4Å; Y91-R114 HydrophobicContact CD2-CG 4.07Å; Y91-R114 HydrophobicContact CE1-CG 3.85Å; Y91-R114 VanDerWaalsContact CE1-O 3.3Å; Y91-R114 WeakPolarHBondContact CE1-O 3.32Å; Y91-R114 HydrophobicContact CE2-CG 3.47Å; Y91-R114 VanDerWaalsContact CE2-CG 3.47Å; Y91-R114 HydrophobicContact CG-CG 4.49Å; T110-R114 PolarHBondContact O-N 2.78Å; D111-R114 PolarHBondContact O-N 3.25Å; R114-K116 PolarHBondContact O-N 3.46Å; R114-A117 PolarHBondContact O-N 3.18Å
115S62.9Low68.6Low94 Ų9475.2 Ų75.266%0.65741%0.414SS*.Hα-helixtrans-67.4-19.7177.470.30000114.4D111 A112D111-S115 WeakPolarHBondContact O-CB 3.41Å; D111-S115 PolarHBondContact O-N 2.94Å; D111-S115 PolarHBondContact O-OG 3.49Å; A112-S115 PolarHBondContact O-OG 2.89Å
116K66.5Low70.1Confident176 Ų17675.3 Ų75.377%0.76541%0.41SS*.Hα-helixtrans-103.2-9.9178.8-72.9-179.91791770113.6H113 R114H113-K116 PolarHBondContact O-N 3.19Å; R114-K116 PolarHBondContact O-N 3.46Å
117A72.9Confident71.5Confident15 Ų1571.7 Ų71.712%0.12439%0.393CS..SBendtrans-67.5130.9179.500000109.8Y91 L93 H113 R114Y91-A117 HydrophobicContact CD1-CB 3.88Å; Y91-A117 HydrophobicContact CG-CB 4.48Å; L93-A117 HydrophobicContact CD2-CB 3.74Å; H113-A117 PolarHBondContact O-N 2.91Å; R114-A117 PolarHBondContact O-N 3.18Å
118P80.3Confident73.1Confident82 Ų8269.8 Ų69.853%0.53238%0.377SS..PPolyproline II helixtrans-64.4141.5175.622.9-25.9000110.2D92D92-P118 HydrophobicContact CB-CG 4.23Å; D92-P118 WeakPolarHBondContact CB-O 3.39Å; D92-P118 PolarHBondContact N-O 2.92Å
119M82.8Confident74.7Confident107 Ų10768.2 Ų68.253%0.52737%0.369SS..EExtended strand (participates in β ladder)trans-90.2136.2176.1-62.4170.6-176.300109.1P75 Y91P75-M119 HydrophobicContact CB-CE 4.14Å; Y91-M119 HydrophobicContact CE1-CE 4.35Å
120T85Confident75.5Confident33 Ų3372.9 Ų72.920%0.20239%0.387CS..EExtended strand (participates in β ladder)trans-135.7159.2175.460.10000111.2Q90 D92Q90-T120 PolarHBondContact N-O 3.36Å; Q90-T120 PolarHBondContact O-N 3.36Å; D92-T120 HydrophobicContact CB-CG2 3.82Å
121S84.7Confident76.4Confident69 Ų6975 Ų7548%0.48339%0.391SS..EExtended strand (participates in β ladder)trans-64.7150.7170.657.50000110.7K123S121-K123 PolarHBondContact O-N 3.31Å
122C85.6Confident77.4Confident21 Ų2171.9 Ų71.914%0.14239%0.389CS..  trans-53.7126.8178.3-46.50000111.8C50 W126C50-C122 WeakPolarHBondContact CA-SG 3.21Å; C50-C122 HydrophobicContact CB-CB 3.62Å; C50-C122 WeakPolarHBondContact CB-SG 3.38Å; C50-C122 VanDerWaalsContact SG-CA 3.54Å; C50-C122 WeakPolarHBondContact SG-CB 3.47Å; C50-C122 CovalentContact SG-SG 2Å; C50-C122 PolarHBondContact SG-SG 3.17Å; C122-W126 HydrophobicContact CB-CE3 4.4Å; C122-W126 HydrophobicContact CB-CH2 3.82Å; C122-W126 HydrophobicContact CB-CZ2 4.06Å; C122-W126 HydrophobicContact CB-CZ3 4.03Å; C122-W126 WeakPolarHBondContact SG-CH2 3.44Å; C122-W126 WeakPolarHBondContact SG-CZ3 3.41Å
123K82.6Confident78.9Confident126 Ų12671.5 Ų71.555%0.54838%0.375SS..SBendtrans-99.7-34.7-177.4-63.9176-172.4163.60113D92 S121D92-K123 IonicContact OD1-NZ 3.99Å; D92-K123 PolarHBondContact OD1-NZ 3.24Å; D92-K123 IonicContact OD2-NZ 3.72Å; D92-K123 PolarHBondContact OD2-NZ 3.22Å; S121-K123 PolarHBondContact O-N 3.31Å
124E82.4Confident80Confident90 Ų9070.4 Ų70.442%0.42137%0.37SS..SBendtrans-110.325-167.5-54.8-170.115600113.8R51 S53R51-E124 VanDerWaalsContact CZ-O 3.3Å; R51-E124 PolarHBondContact NE-O 3.14Å; R51-E124 PolarHBondContact NH2-O 3.03Å; R51-E124 WeakPolarHBondContact O-CB 3.46Å; S53-E124 WeakPolarHBondContact CB-OE2 3.35Å; S53-E124 PolarHBondContact N-OE2 3.12Å; S53-E124 PolarHBondContact OG-OE2 3.49Å
125G84.2Confident81.3Confident16 Ų1668.6 Ų68.617%0.16536%0.364CS..  trans90.6-158.117900000113.5R51R51-G125 PolarHBondContact N-O 3.33Å
126W88Confident82.8Confident37 Ų3764.1 Ų64.114%0.1433%0.333CS..EExtended strand (participates in β ladder)trans-129.8147.3-167.3-52.995.2000112.3H48 W49 Q87 C122 Y128 V143 C144H48-W126 AromaticContact CD2-CE3 3.77Å; H48-W126 AromaticContact CD2-CZ3 3.83Å; W49-W126 CarbonylContact O-C 3.6Å; W49-W126 WeakPolarHBondContact O-CA 3.42Å; Q87-W126 WeakPolarHBondContact O-CZ3 3.41Å; C122-W126 HydrophobicContact CB-CE3 4.4Å; C122-W126 HydrophobicContact CB-CH2 3.82Å; C122-W126 HydrophobicContact CB-CZ2 4.06Å; C122-W126 HydrophobicContact CB-CZ3 4.03Å; C122-W126 WeakPolarHBondContact SG-CH2 3.44Å; C122-W126 WeakPolarHBondContact SG-CZ3 3.41Å; W126-Y128 HydrophobicContact CB-CD2 4.4Å; W126-Y128 HydrophobicContact CB-CE1 4.15Å; W126-Y128 HydrophobicContact CB-CE2 3.66Å; W126-Y128 VanDerWaalsContact CB-CZ 3.49Å; W126-Y128 WeakPolarHBondContact CB-OH 3.31Å; W126-V143 HydrophobicContact CD2-CG2 3.35Å; W126-V143 HydrophobicContact CE3-CG2 3.7Å; W126-V143 HydrophobicContact CG-CG2 3.82Å; W126-V143 HydrophobicContact CH2-CG2 4.02Å; W126-V143 HydrophobicContact CZ2-CG2 3.69Å; W126-V143 HydrophobicContact CZ3-CG2 3.99Å; W126-C144 HydrophobicContact CH2-CB 3.64Å; W126-C144 WeakPolarHBondContact CH2-SG 3.22Å; W126-C144 HydrophobicContact CZ2-CB 4.12Å; W126-C144 HydrophobicContact CZ3-CB 4.46Å; W126-C144 WeakPolarHBondContact CZ3-SG 3.06Å
127E86.2Confident83.9Confident43 Ų4355.7 Ų55.720%0.20130%0.296CS..EExtended strand (participates in β ladder)trans-108126.6162.8-74.8-169.2-169.600108.9H48 W49 R51 R59H48-E127 VanDerWaalsContact CA-O 3.3Å; H48-E127 WeakPolarHBondContact CA-O 3.37Å; W49-E127 PolarHBondContact N-O 3.28Å; W49-E127 PolarHBondContact O-N 3.31Å; R51-E127 HydrophobicContact CB-CG 4.03Å; R51-E127 HydrophobicContact CG-CG 4.02Å; R59-E127 IonicContact NH1-OE1 3.38Å; R59-E127 IonicContact NH1-OE2 3.25Å; R59-E127 PolarHBondContact NH1-OE2 2.78Å
128Y87.2Confident84.7Confident16 Ų1655.5 Ų55.56%0.06329%0.293CS..EExtended strand (participates in β ladder)trans-107.9143.5-178.8-59.4-81000111.4P46 H48 W126 Y130 T138 D141 V143P46-Y128 HydrophobicContact CG-CD1 3.96Å; P46-Y128 HydrophobicContact CG-CG 4.42Å; H48-Y128 HydrophobicContact CB-CD1 3.5Å; H48-Y128 HydrophobicContact CB-CE1 3.65Å; H48-Y128 HydrophobicContact CB-CG 4.47Å; W126-Y128 HydrophobicContact CB-CD2 4.4Å; W126-Y128 HydrophobicContact CB-CE1 4.15Å; W126-Y128 HydrophobicContact CB-CE2 3.66Å; W126-Y128 VanDerWaalsContact CB-CZ 3.49Å; W126-Y128 WeakPolarHBondContact CB-OH 3.31Å; Y128-Y130 WeakPolarHBondContact O-CD2 3.44Å; Y128-Y130 PolarHBondContact O-N 2.88Å; Y128-T138 HydrophobicContact CD1-CG2 3.78Å; Y128-T138 HydrophobicContact CD2-CG2 4.19Å; Y128-T138 HydrophobicContact CE1-CG2 4.2Å; Y128-T138 HydrophobicContact CG-CG2 3.79Å; Y128-D141 VanDerWaalsContact CE2-OD1 3.25Å; Y128-D141 WeakPolarHBondContact CE2-OD1 3.39Å; Y128-D141 WeakPolarHBondContact OH-CA 3.39Å; Y128-D141 PolarHBondContact OH-OD1 3.14Å; Y128-V143 HydrophobicContact CE1-CG1 3.9Å; Y128-V143 HydrophobicContact CE1-CG2 4.41Å
129D84.1Confident85.2Confident70 Ų7055.5 Ų55.537%0.37429%0.286SS..  trans-85.296.5161.4-162.3-20.4000109.5P46 E47 W49 E131P46-D129 WeakPolarHBondContact CB-O 3.36Å; E47-D129 PolarHBondContact O-N 2.97Å; W49-D129 HydrophobicContact CH2-CB 4.14Å; W49-D129 HydrophobicContact CZ3-CB 3.96Å; D129-E131 PolarHBondContact O-N 3.42Å; D129-E131 PolarHBondContact OD1-N 3.19Å
130Y76Confident85.6Confident109 Ų10952.4 Ų52.443%0.42727%0.27SS..  trans-67-21.1-171.4-68.4-83.8000113.5Y128 G132 R133 T138Y128-Y130 WeakPolarHBondContact O-CD2 3.44Å; Y128-Y130 PolarHBondContact O-N 2.88Å; Y130-G132 PolarHBondContact O-N 3.36Å; Y130-R133 PolarHBondContact O-N 3.25Å; Y130-R133 VanDerWaalsContact O-O 3.12Å; Y130-T138 HydrophobicContact CE1-CG2 4.23Å
131E76.3Confident85.9Confident122 Ų12253.9 Ų53.957%0.5728%0.276SS*.THydrogen-bonded Turntrans46.427.2-173.2-60.2-175.5159.100113.9D129 R133D129-E131 PolarHBondContact O-N 3.42Å; D129-E131 PolarHBondContact OD1-N 3.19Å; E131-R133 IonicContact OE2-CZ 2.82Å; E131-R133 IonicContact OE2-NH2 3.94Å; E131-R133 PolarHBondContact OE2-NH2 3.22Å
132G79Confident86.2Confident59 Ų5951.1 Ų51.161%0.60826%0.256SS*.THydrogen-bonded Turntrans76.111.8-17500000116.2Y130 T261Y130-G132 PolarHBondContact O-N 3.36Å; G132-T261 VanDerWaalsContact O-CB 3.31Å; G132-T261 WeakPolarHBondContact O-CB 3.43Å; G132-T261 PolarHBondContact O-OG1 2.98Å
133R82.9Confident86.4Confident47 Ų4750.3 Ų50.318%0.17725%0.251CS..  trans-120.7142.7-178.6-63-178.5-73.4159.3-2.9111.7F44 Y130 E131 T261F44-R133 VanDerWaalsContact CE1-NH2 3.26Å; F44-R133 VanDerWaalsContact CZ-NH2 3.3Å; Y130-R133 PolarHBondContact O-N 3.25Å; Y130-R133 VanDerWaalsContact O-O 3.12Å; E131-R133 IonicContact OE2-CZ 2.82Å; E131-R133 IonicContact OE2-NH2 3.94Å; E131-R133 PolarHBondContact OE2-NH2 3.22Å; R133-T261 HydrophobicContact CG-CG2 4.22Å
134Q86.6Confident86.6Confident104 Ų10445.7 Ų45.749%0.48623%0.234SC..BIsolated β-bridgetrans-116.3126.5174.5-63.7-170.7-3.600109.7T261 D262 W263Q134-T261 PolarHBondContact N-O 3.38Å; Q134-D262 PolarHBondContact OE1-OD1 3.03Å; Q134-W263 WeakPolarHBondContact O-CB 3.24Å; Q134-W263 PolarHBondContact O-N 3.12Å
135S91.9Very high86.8Confident4 Ų447.4 Ų47.43%0.02825%0.246CC..  trans-117.5157.3178.374.90000111Q42 F44 V137 T138 E139Q42-S135 WeakPolarHBondContact O-CA 3.27Å; Q42-S135 VanDerWaalsContact O-CB 3.26Å; Q42-S135 WeakPolarHBondContact O-CB 3.48Å; F44-S135 WeakPolarHBondContact O-CB 3.35Å; F44-S135 PolarHBondContact O-OG 3Å; S135-V137 PolarHBondContact O-N 3.18Å; S135-V137 PolarHBondContact OG-N 3.32Å; S135-T138 PolarHBondContact N-OG1 3.07Å; S135-T138 VanDerWaalsContact N-OG1 3.16Å; S135-T138 PolarHBondContact O-N 3.28Å; S135-T138 VanDerWaalsContact O-N 3.14Å; S135-T138 PolarHBondContact O-OG1 2.95Å; S135-T138 PolarHBondContact OG-N 3.02Å; S135-T138 PolarHBondContact OG-OG1 3.41Å; S135-E139 PolarHBondContact O-N 2.98Å; S135-E139 VanDerWaalsContact O-N 3.11Å
136F92.8Very high87Confident0 Ų050.6 Ų50.60%026%0.259CS..Hα-helixtrans-63.6-22.9174.370.5-103.1000111.5Q42 E139 F140 L142 V150 Y153 Y201 M204 W263Q42-F136 VanDerWaalsContact C-CD1 3.49Å; Q42-F136 HydrophobicContact CB-CD1 4.06Å; Q42-F136 HydrophobicContact CB-CE1 4.17Å; Q42-F136 WeakPolarHBondContact O-CD1 3.44Å; Q42-F136 PolarHBondContact O-N 3.07Å; F136-E139 PolarHBondContact O-N 2.98Å; F136-F140 HydrophobicContact CB-CD2 4.22Å; F136-F140 HydrophobicContact CB-CE2 4.36Å; F136-F140 VanDerWaalsContact O-CD2 3.27Å; F136-F140 WeakPolarHBondContact O-CD2 3.49Å; F136-F140 PolarHBondContact O-N 2.95Å; F136-L142 HydrophobicContact CD2-CD1 3.99Å; F136-L142 HydrophobicContact CE2-CD1 4.15Å; F136-V150 HydrophobicContact CE2-CG1 3.97Å; F136-V150 HydrophobicContact CZ-CG1 3.92Å; F136-Y153 HydrophobicContact CE1-CD1 4.16Å; F136-Y153 HydrophobicContact CE1-CD2 4.39Å; F136-Y153 HydrophobicContact CE1-CE1 4.29Å; F136-Y153 HydrophobicContact CE1-CG 4.19Å; F136-Y153 HydrophobicContact CZ-CD1 4.23Å; F136-Y153 HydrophobicContact CZ-CD2 4.29Å; F136-Y153 AromaticContact CZ-CG 3.95Å; F136-Y153 HydrophobicContact CZ-CG 3.95Å; F136-Y201 AromaticContact CD2-CE2 3.92Å; F136-Y201 HydrophobicContact CD2-CE2 3.92Å; F136-Y201 AromaticContact CE2-CE2 3.97Å; F136-Y201 HydrophobicContact CE2-CE2 3.97Å; F136-M204 HydrophobicContact CB-CE 3.98Å; F136-M204 HydrophobicContact CB-SD 4.25Å; F136-M204 HydrophobicContact CD1-CE 4.5Å; F136-M204 HydrophobicContact CD2-CE 3.72Å; F136-M204 HydrophobicContact CE2-CE 4.35Å; F136-M204 HydrophobicContact CG-CE 3.82Å; F136-W263 HydrophobicContact CB-CD2 3.89Å; F136-W263 HydrophobicContact CB-CE3 4.2Å; F136-W263 HydrophobicContact CB-CG 4.44Å; F136-W263 HydrophobicContact CB-CH2 4.2Å; F136-W263 HydrophobicContact CB-CZ2 3.88Å; F136-W263 HydrophobicContact CB-CZ3 4.35Å
137V91Very high86.9Confident0 Ų050.5 Ų50.50%027%0.267CS..Hα-helixtrans-66-45.3175.4179.30000110.5T45 S135 E139 D141 L142 V143 V150T45-V137 HydrophobicContact CG2-CB 4.46Å; T45-V137 HydrophobicContact CG2-CG1 3.82Å; T45-V137 HydrophobicContact CG2-CG2 4.33Å; S135-V137 PolarHBondContact O-N 3.18Å; S135-V137 PolarHBondContact OG-N 3.32Å; V137-E139 VanDerWaalsContact C-N 3.31Å; V137-E139 PolarHBondContact O-N 2.95Å; V137-D141 WeakPolarHBondContact O-CA 3.23Å; V137-D141 PolarHBondContact O-N 3.29Å; V137-L142 HydrophobicContact CG1-CB 4.09Å; V137-L142 WeakPolarHBondContact CG1-O 3.3Å; V137-L142 PolarHBondContact O-N 3.49Å; V137-V143 HydrophobicContact CG1-CG1 3.86Å; V137-V150 HydrophobicContact CG1-CG2 4.37Å; V137-V150 HydrophobicContact CG2-CG1 3.87Å; V137-V150 HydrophobicContact CG2-CG2 3.82Å
138T89.8Confident87Confident11 Ų1153.7 Ų53.77%0.06728%0.277CS..Hα-helixtrans-70-26.6175.956.10000113.7P46 Y128 Y130 S135P46-T138 HydrophobicContact CG-CG2 3.31Å; Y128-T138 HydrophobicContact CD1-CG2 3.78Å; Y128-T138 HydrophobicContact CD2-CG2 4.19Å; Y128-T138 HydrophobicContact CE1-CG2 4.2Å; Y128-T138 HydrophobicContact CG-CG2 3.79Å; Y130-T138 HydrophobicContact CE1-CG2 4.23Å; S135-T138 PolarHBondContact N-OG1 3.07Å; S135-T138 VanDerWaalsContact N-OG1 3.16Å; S135-T138 PolarHBondContact O-N 3.28Å; S135-T138 VanDerWaalsContact O-N 3.14Å; S135-T138 PolarHBondContact O-OG1 2.95Å; S135-T138 PolarHBondContact OG-N 3.02Å; S135-T138 PolarHBondContact OG-OG1 3.41Å
139E90.9Very high87.2Confident82 Ų8253.9 Ų53.938%0.38328%0.279SS..Hα-helixtrans-80.8-33.6-178.9-170.7173.1164.100112.7S135 F136 V137 W263 R264S135-E139 PolarHBondContact O-N 2.98Å; S135-E139 VanDerWaalsContact O-N 3.11Å; F136-E139 PolarHBondContact O-N 2.98Å; V137-E139 VanDerWaalsContact C-N 3.31Å; V137-E139 PolarHBondContact O-N 2.95Å; E139-W263 VanDerWaalsContact OE2-CE2 3.23Å; E139-W263 WeakPolarHBondContact OE2-CZ2 3.47Å; E139-W263 PolarHBondContact OE2-NE1 3.39Å; E139-R264 IonicContact OE1-CZ 3.56Å; E139-R264 VanDerWaalsContact OE1-CZ 3.25Å; E139-R264 IonicContact OE1-NE 2.86Å; E139-R264 PolarHBondContact OE1-NE 3.4Å; E139-R264 VanDerWaalsContact OE1-NE 3.1Å; E139-R264 IonicContact OE1-NH2 2.74Å; E139-R264 PolarHBondContact OE1-NH2 2.85Å; E139-R264 IonicContact OE2-CZ 3.86Å; E139-R264 IonicContact OE2-NE 3.96Å; E139-R264 PolarHBondContact OE2-NE 3.44Å; E139-R264 VanDerWaalsContact OE2-NE 3.16Å; E139-R264 IonicContact OE2-NH2 3.05Å
140F91.4Very high87.5Confident42 Ų4251 Ų5118%0.18426%0.264CS..THydrogen-bonded Turntrans-106.210.6-179.4-63-61.4000113.9F136 L142 Y201 M204 W263F136-F140 HydrophobicContact CB-CD2 4.22Å; F136-F140 HydrophobicContact CB-CE2 4.36Å; F136-F140 VanDerWaalsContact O-CD2 3.27Å; F136-F140 WeakPolarHBondContact O-CD2 3.49Å; F136-F140 PolarHBondContact O-N 2.95Å; F140-L142 HydrophobicContact CB-CD1 3.98Å; F140-L142 HydrophobicContact CB-CD2 4.15Å; F140-L142 HydrophobicContact CB-CG 3.79Å; F140-L142 PolarHBondContact O-N 3.31Å; F140-Y201 HydrophobicContact CB-CD2 4.46Å; F140-Y201 AromaticContact CD2-CD2 3.82Å; F140-Y201 HydrophobicContact CD2-CD2 3.82Å; F140-Y201 HydrophobicContact CE2-CD2 4.38Å; F140-Y201 HydrophobicContact CG-CD2 4.27Å; F140-M204 HydrophobicContact CD2-CE 4.24Å; F140-M204 HydrophobicContact CE2-CE 4Å; F140-M204 HydrophobicContact CE2-SD 3.92Å; F140-W263 HydrophobicContact CE2-CH2 4.42Å; F140-W263 HydrophobicContact CE2-CZ2 4.23Å
141D90.9Very high88.3Confident63 Ų6346 Ų4634%0.33725%0.245SC..THydrogen-bonded Turntrans54.242.9178.6-72.5-38.9000115.2Y128 V137 V143Y128-D141 VanDerWaalsContact CE2-OD1 3.25Å; Y128-D141 WeakPolarHBondContact CE2-OD1 3.39Å; Y128-D141 WeakPolarHBondContact OH-CA 3.39Å; Y128-D141 PolarHBondContact OH-OD1 3.14Å; V137-D141 WeakPolarHBondContact O-CA 3.23Å; V137-D141 PolarHBondContact O-N 3.29Å; D141-V143 VanDerWaalsContact C-N 3.32Å; D141-V143 PolarHBondContact O-N 3.1Å; D141-V143 VanDerWaalsContact O-N 3.11Å
142L90.8Very high89.1Confident12 Ų1243.1 Ų43.16%0.06323%0.232CC..  trans-90.555.8-171.7-53.9171.5000113.1F136 V137 F140 V149 V150 Y201F136-L142 HydrophobicContact CD2-CD1 3.99Å; F136-L142 HydrophobicContact CE2-CD1 4.15Å; V137-L142 HydrophobicContact CG1-CB 4.09Å; V137-L142 WeakPolarHBondContact CG1-O 3.3Å; V137-L142 PolarHBondContact O-N 3.49Å; F140-L142 HydrophobicContact CB-CD1 3.98Å; F140-L142 HydrophobicContact CB-CD2 4.15Å; F140-L142 HydrophobicContact CB-CG 3.79Å; F140-L142 PolarHBondContact O-N 3.31Å; L142-V149 HydrophobicContact CD2-CB 4.48Å; L142-V149 HydrophobicContact CD2-CG1 4.21Å; L142-V150 HydrophobicContact CB-CG2 3.6Å; L142-V150 HydrophobicContact CD1-CG2 4.19Å; L142-V150 WeakPolarHBondContact O-CG2 3.26Å; L142-Y201 HydrophobicContact CD1-CD2 3.45Å; L142-Y201 VanDerWaalsContact CD1-CD2 3.45Å; L142-Y201 HydrophobicContact CD1-CE1 4.39Å; L142-Y201 HydrophobicContact CD1-CE2 3.25Å; L142-Y201 HydrophobicContact CD1-CG 4.1Å; L142-Y201 HydrophobicContact CD2-CG 4.45Å
143V89.3Confident89.9Confident4 Ų440.3 Ų40.32%0.02420%0.203CC..  trans-117.8167-179.3-64.30000112.2W126 Y128 V137 D141 N145 D146W126-V143 HydrophobicContact CD2-CG2 3.35Å; W126-V143 HydrophobicContact CE3-CG2 3.7Å; W126-V143 HydrophobicContact CG-CG2 3.82Å; W126-V143 HydrophobicContact CH2-CG2 4.02Å; W126-V143 HydrophobicContact CZ2-CG2 3.69Å; W126-V143 HydrophobicContact CZ3-CG2 3.99Å; Y128-V143 HydrophobicContact CE1-CG1 3.9Å; Y128-V143 HydrophobicContact CE1-CG2 4.41Å; V137-V143 HydrophobicContact CG1-CG1 3.86Å; D141-V143 VanDerWaalsContact C-N 3.32Å; D141-V143 PolarHBondContact O-N 3.1Å; D141-V143 VanDerWaalsContact O-N 3.11Å; V143-N145 PolarHBondContact O-N 3.28Å; V143-N145 VanDerWaalsContact O-N 3.07Å; V143-D146 PolarHBondContact O-N 2.86Å
144C86.6Confident90.3Very high28 Ų2838.1 Ų38.119%0.18920%0.195CC..G310 helixtrans54.4-110.1177.2-57.50000113.6H48 C88 W126 D146 A147H48-C144 PolarHBondContact NE2-SG 3.49Å; H48-C144 VanDerWaalsContact NE2-SG 3.43Å; C88-C144 WeakPolarHBondContact CA-SG 3.43Å; C88-C144 HydrophobicContact CB-CB 3.7Å; C88-C144 WeakPolarHBondContact CB-SG 3.15Å; C88-C144 WeakPolarHBondContact SG-CB 3.29Å; C88-C144 CovalentContact SG-SG 2.02Å; C88-C144 PolarHBondContact SG-SG 2.49Å; W126-C144 HydrophobicContact CH2-CB 3.64Å; W126-C144 WeakPolarHBondContact CH2-SG 3.22Å; W126-C144 HydrophobicContact CZ2-CB 4.12Å; W126-C144 HydrophobicContact CZ3-CB 4.46Å; W126-C144 WeakPolarHBondContact CZ3-SG 3.06Å; C144-D146 PolarHBondContact O-N 3.13Å; C144-A147 VanDerWaalsContact O-CB 3.26Å; C144-A147 WeakPolarHBondContact O-CB 3.32Å; C144-A147 PolarHBondContact O-N 2.74Å; C144-A147 VanDerWaalsContact O-N 3.15Å
145N86.4Confident90.8Very high127 Ų12733.4 Ų33.468%0.67917%0.174SC*.G310 helixtrans-61.7-29.5-179.2-74-21.6000112.7V143 W148V143-N145 PolarHBondContact O-N 3.28Å; V143-N145 VanDerWaalsContact O-N 3.07Å; N145-W148 PolarHBondContact O-NE1 2.98Å
146D87.9Confident91Very high82 Ų8234.5 Ų34.544%0.43918%0.181SC..G310 helixtrans-97.44.6-179.3-66.6-42.3000113V143 C144 W148 V149V143-D146 PolarHBondContact O-N 2.86Å; C144-D146 PolarHBondContact O-N 3.13Å; D146-W148 PolarHBondContact O-N 3.41Å; D146-W148 VanDerWaalsContact O-N 3.17Å; D146-V149 HydrophobicContact CB-CG2 4.48Å; D146-V149 WeakPolarHBondContact O-CB 3.38Å; D146-V149 WeakPolarHBondContact O-CG2 3.32Å; D146-V149 PolarHBondContact O-N 2.97Å
147A86.8Confident91.1Very high36 Ų3634.5 Ų34.530%0.29818%0.181SC..Hα-helixtrans-59.5-31.8-179.100000113.5C144 V149 V150C144-A147 VanDerWaalsContact O-CB 3.26Å; C144-A147 WeakPolarHBondContact O-CB 3.32Å; C144-A147 PolarHBondContact O-N 2.74Å; C144-A147 VanDerWaalsContact O-N 3.15Å; A147-V149 PolarHBondContact O-N 3.34Å; A147-V150 WeakPolarHBondContact O-CB 3.38Å; A147-V150 WeakPolarHBondContact O-CG2 3.35Å; A147-V150 PolarHBondContact O-N 3.23Å
148W88.3Confident91.3Very high110 Ų11034.7 Ų34.742%0.41718%0.182SC..Hα-helixtrans-65.6-21.417770.3-83.3000113N145 D146 V150 D151 M152N145-W148 PolarHBondContact O-NE1 2.98Å; D146-W148 PolarHBondContact O-N 3.41Å; D146-W148 VanDerWaalsContact O-N 3.17Å; W148-V150 VanDerWaalsContact C-N 3.26Å; W148-V150 PolarHBondContact O-N 3.15Å; W148-D151 WeakPolarHBondContact O-CB 3.3Å; W148-D151 PolarHBondContact O-N 3.15Å; W148-M152 HydrophobicContact CE3-CE 4.42Å; W148-M152 HydrophobicContact CE3-SD 4.31Å; W148-M152 HydrophobicContact CH2-CE 4.12Å; W148-M152 HydrophobicContact CH2-SD 4.22Å; W148-M152 HydrophobicContact CZ3-CE 3.48Å; W148-M152 VanDerWaalsContact CZ3-CE 3.48Å; W148-M152 HydrophobicContact CZ3-CG 4.36Å; W148-M152 HydrophobicContact CZ3-SD 3.67Å
149V91.5Very high91.6Very high19 Ų1937 Ų3712%0.11520%0.195CC..Hα-helixtrans-71.7-27.3179.8179.40000110.1L142 D146 A147 D151 M152 Y201L142-V149 HydrophobicContact CD2-CB 4.48Å; L142-V149 HydrophobicContact CD2-CG1 4.21Å; D146-V149 HydrophobicContact CB-CG2 4.48Å; D146-V149 WeakPolarHBondContact O-CB 3.38Å; D146-V149 WeakPolarHBondContact O-CG2 3.32Å; D146-V149 PolarHBondContact O-N 2.97Å; A147-V149 PolarHBondContact O-N 3.34Å; V149-D151 VanDerWaalsContact C-N 3.31Å; V149-D151 PolarHBondContact O-N 3.06Å; V149-M152 HydrophobicContact CG1-SD 4.49Å; V149-M152 VanDerWaalsContact O-CB 3.25Å; V149-M152 WeakPolarHBondContact O-CB 3.18Å; V149-M152 PolarHBondContact O-N 3.43Å; V149-Y201 HydrophobicContact CB-CE1 4.4Å; V149-Y201 HydrophobicContact CG1-CD1 3.55Å; V149-Y201 HydrophobicContact CG1-CE1 3.09Å; V149-Y201 PolarHBondContact O-OH 3.02Å
150V91.4Very high91.8Very high10 Ų1033.1 Ų33.16%0.06118%0.178CC..Hα-helixtrans-61.3-40.2173.6-1770000111.1F136 V137 L142 A147 W148 M152 Y153F136-V150 HydrophobicContact CE2-CG1 3.97Å; F136-V150 HydrophobicContact CZ-CG1 3.92Å; V137-V150 HydrophobicContact CG1-CG2 4.37Å; V137-V150 HydrophobicContact CG2-CG1 3.87Å; V137-V150 HydrophobicContact CG2-CG2 3.82Å; L142-V150 HydrophobicContact CB-CG2 3.6Å; L142-V150 HydrophobicContact CD1-CG2 4.19Å; L142-V150 WeakPolarHBondContact O-CG2 3.26Å; A147-V150 WeakPolarHBondContact O-CB 3.38Å; A147-V150 WeakPolarHBondContact O-CG2 3.35Å; A147-V150 PolarHBondContact O-N 3.23Å; W148-V150 VanDerWaalsContact C-N 3.26Å; W148-V150 PolarHBondContact O-N 3.15Å; V150-M152 PolarHBondContact O-N 3.41Å; V150-Y153 WeakPolarHBondContact O-CB 3.45Å; V150-Y153 PolarHBondContact O-N 3.05Å
151D91.8Very high91.9Very high4 Ų431.3 Ų31.32%0.02117%0.17CC..Hα-helixtrans-59.2-31.4178.2-55.3-20.4000111.8W148 V149 Y153 Q154 A155 P481 F482 Y485W148-D151 WeakPolarHBondContact O-CB 3.3Å; W148-D151 PolarHBondContact O-N 3.15Å; V149-D151 VanDerWaalsContact C-N 3.31Å; V149-D151 PolarHBondContact O-N 3.06Å; D151-Y153 PolarHBondContact O-N 3.25Å; D151-Q154 PolarHBondContact O-N 3.03Å; D151-A155 PolarHBondContact O-N 2.89Å; D151-A155 VanDerWaalsContact O-N 3.12Å; D151-P481 HydrophobicContact CB-CB 4.15Å; D151-F482 HydrophobicContact CB-CD1 3.58Å; D151-F482 HydrophobicContact CB-CE1 3.51Å; D151-F482 HydrophobicContact CB-CG 4.26Å; D151-F482 HydrophobicContact CB-CZ 4.15Å; D151-Y485 WeakPolarHBondContact OD1-CB 3.25Å; D151-Y485 WeakPolarHBondContact OD1-CD2 3.19Å
152M94Very high92Very high61 Ų6130.1 Ų30.130%0.316%0.163SC..Hα-helixtrans-62.3-26.3177.2-59.3-174.6124.900112.4W148 V149 V150 Q154 A155 T156 L205 F482W148-M152 HydrophobicContact CE3-CE 4.42Å; W148-M152 HydrophobicContact CE3-SD 4.31Å; W148-M152 HydrophobicContact CH2-CE 4.12Å; W148-M152 HydrophobicContact CH2-SD 4.22Å; W148-M152 HydrophobicContact CZ3-CE 3.48Å; W148-M152 VanDerWaalsContact CZ3-CE 3.48Å; W148-M152 HydrophobicContact CZ3-CG 4.36Å; W148-M152 HydrophobicContact CZ3-SD 3.67Å; V149-M152 HydrophobicContact CG1-SD 4.49Å; V149-M152 VanDerWaalsContact O-CB 3.25Å; V149-M152 WeakPolarHBondContact O-CB 3.18Å; V149-M152 PolarHBondContact O-N 3.43Å; V150-M152 PolarHBondContact O-N 3.41Å; M152-Q154 VanDerWaalsContact C-N 3.32Å; M152-Q154 PolarHBondContact O-N 3.4Å; M152-A155 PolarHBondContact O-N 3Å; M152-T156 VanDerWaalsContact O-CB 3.28Å; M152-T156 WeakPolarHBondContact O-CB 3.39Å; M152-T156 WeakPolarHBondContact O-CG2 3.48Å; M152-T156 PolarHBondContact O-N 3.13Å; M152-T156 PolarHBondContact O-OG1 3.32Å; M152-L205 HydrophobicContact CB-CD1 4.08Å; M152-L205 HydrophobicContact CB-CD2 4.23Å; M152-L205 HydrophobicContact SD-CD1 4.43Å; M152-F482 HydrophobicContact CG-CE1 4.45Å; M152-F482 HydrophobicContact CG-CZ 4.15Å
153Y94.1Very high92.1Very high0 Ų032.9 Ų32.90%018%0.181CC..Hα-helixtrans-59.3-43.6179-172.9-99000112.1I39 Q42 F136 V150 D151 T156 M204 L205 R208I39-Y153 HydrophobicContact CB-CD1 4.28Å; I39-Y153 HydrophobicContact CB-CE1 4.48Å; I39-Y153 HydrophobicContact CD1-CD1 3.96Å; I39-Y153 HydrophobicContact CG1-CD1 4.01Å; Q42-Y153 PolarHBondContact OE1-OH 3.31Å; F136-Y153 HydrophobicContact CE1-CD1 4.16Å; F136-Y153 HydrophobicContact CE1-CD2 4.39Å; F136-Y153 HydrophobicContact CE1-CE1 4.29Å; F136-Y153 HydrophobicContact CE1-CG 4.19Å; F136-Y153 HydrophobicContact CZ-CD1 4.23Å; F136-Y153 HydrophobicContact CZ-CD2 4.29Å; F136-Y153 AromaticContact CZ-CG 3.95Å; F136-Y153 HydrophobicContact CZ-CG 3.95Å; V150-Y153 WeakPolarHBondContact O-CB 3.45Å; V150-Y153 PolarHBondContact O-N 3.05Å; D151-Y153 PolarHBondContact O-N 3.25Å; Y153-T156 PolarHBondContact O-OG1 2.94Å; Y153-M204 HydrophobicContact CD2-CE 3.74Å; Y153-M204 HydrophobicContact CE2-CE 3.78Å; Y153-M204 HydrophobicContact CE2-CG 4.05Å; Y153-M204 HydrophobicContact CE2-SD 3.99Å; Y153-L205 HydrophobicContact CD2-CD2 4.41Å; Y153-R208 HydrophobicContact CD2-CG 4.24Å; Y153-R208 HydrophobicContact CE2-CB 4.45Å; Y153-R208 HydrophobicContact CE2-CG 4.04Å; Y153-R208 VanDerWaalsContact CZ-NE 3.27Å; Y153-R208 WeakPolarHBondContact O-CG 3.28Å; Y153-R208 PolarHBondContact OH-NE 3.11Å
154Q93.2Very high92.2Very high1 Ų132.7 Ų32.71%0.00518%0.179CC..Hα-helixtrans-84.7-33.2177.6-165.164.924.100112.1Y36 I39 D151 M152 L157 N158 M366 P481Y36-Q154 PolarHBondContact O-NE2 3.2Å; I39-Q154 HydrophobicContact CD1-CB 3.73Å; D151-Q154 PolarHBondContact O-N 3.03Å; M152-Q154 VanDerWaalsContact C-N 3.32Å; M152-Q154 PolarHBondContact O-N 3.4Å; Q154-L157 WeakPolarHBondContact O-CB 3.24Å; Q154-L157 PolarHBondContact O-N 3.03Å; Q154-N158 PolarHBondContact O-N 2.82Å; Q154-N158 PolarHBondContact O-ND2 3.16Å; Q154-M366 HydrophobicContact CG-SD 4.16Å; Q154-P481 HydrophobicContact CB-CB 4.36Å; Q154-P481 HydrophobicContact CB-CG 3.69Å; Q154-P481 HydrophobicContact CG-CG 3.91Å
155A95.3Very high92.2Very high6 Ų631.7 Ų31.75%0.0517%0.172CC..Hα-helixtrans-62.9-45.2176.900000111.8D151 M152 L157 N158 V159 I478 F482D151-A155 PolarHBondContact O-N 2.89Å; D151-A155 VanDerWaalsContact O-N 3.12Å; M152-A155 PolarHBondContact O-N 3Å; A155-L157 VanDerWaalsContact C-N 3.33Å; A155-L157 PolarHBondContact O-N 3.47Å; A155-N158 PolarHBondContact O-N 3.2Å; A155-N158 VanDerWaalsContact O-N 3.12Å; A155-V159 WeakPolarHBondContact O-CG2 3.48Å; A155-V159 PolarHBondContact O-N 2.81Å; A155-I478 HydrophobicContact CB-CG2 4.27Å; A155-F482 HydrophobicContact CB-CD2 4.43Å; A155-F482 HydrophobicContact CB-CE2 3.48Å; A155-F482 VanDerWaalsContact CB-CE2 3.48Å; A155-F482 HydrophobicContact CB-CZ 3.98Å
156T96Very high92.1Very high27 Ų2730.6 Ų30.617%0.16617%0.166CC..Hα-helixtrans-65.2-34.3178.154.30000112.7M152 Y153 N158 V159 G160 L205 T209M152-T156 VanDerWaalsContact O-CB 3.28Å; M152-T156 WeakPolarHBondContact O-CB 3.39Å; M152-T156 WeakPolarHBondContact O-CG2 3.48Å; M152-T156 PolarHBondContact O-N 3.13Å; M152-T156 PolarHBondContact O-OG1 3.32Å; Y153-T156 PolarHBondContact O-OG1 2.94Å; T156-N158 VanDerWaalsContact C-N 3.34Å; T156-N158 PolarHBondContact O-N 3.18Å; T156-V159 PolarHBondContact O-N 3.08Å; T156-G160 PolarHBondContact O-N 3.21Å; T156-L205 HydrophobicContact CG2-CB 4.38Å; T156-L205 HydrophobicContact CG2-CD2 4.34Å; T156-T209 WeakPolarHBondContact CB-OG1 3.43Å
157L95.3Very high92.2Very high0 Ų029.1 Ų29.10%016%0.16CC..Hα-helixtrans-57.9-47.6169.7-175.473.7000111.4V35 Q154 A155 G160 F161 R208V35-L157 HydrophobicContact CG1-CD1 4.03Å; V35-L157 HydrophobicContact CG1-CD2 4.46Å; V35-L157 WeakPolarHBondContact O-CD2 3.29Å; Q154-L157 WeakPolarHBondContact O-CB 3.24Å; Q154-L157 PolarHBondContact O-N 3.03Å; A155-L157 VanDerWaalsContact C-N 3.33Å; A155-L157 PolarHBondContact O-N 3.47Å; L157-G160 CarbonylContact O-C 3.58Å; L157-G160 WeakPolarHBondContact O-CA 3.2Å; L157-G160 PolarHBondContact O-N 3.26Å; L157-G160 VanDerWaalsContact O-N 3.1Å; L157-F161 HydrophobicContact CD1-CE1 4.17Å; L157-F161 HydrophobicContact CD1-CZ 4.47Å; L157-F161 HydrophobicContact CD2-CE1 4.4Å; L157-F161 HydrophobicContact CD2-CE2 4.37Å; L157-F161 HydrophobicContact CD2-CZ 3.9Å; L157-F161 HydrophobicContact CG-CE1 4.01Å; L157-F161 HydrophobicContact CG-CZ 3.98Å; L157-F161 PolarHBondContact O-N 3.38Å; L157-R208 HydrophobicContact CB-CG 4.28Å; L157-R208 HydrophobicContact CD1-CG 4.4Å; L157-R208 VanDerWaalsContact CD1-NH1 3.33Å
158N95Very high92.1Very high3 Ų327.5 Ų27.52%0.01615%0.146CC..Hα-helixtrans-70.3-31.3-179.8-73.4-61.1000112.7Q154 A155 T156 G160 F161 L162 Q362 G477 I478Q154-N158 PolarHBondContact O-N 2.82Å; Q154-N158 PolarHBondContact O-ND2 3.16Å; A155-N158 PolarHBondContact O-N 3.2Å; A155-N158 VanDerWaalsContact O-N 3.12Å; T156-N158 VanDerWaalsContact C-N 3.34Å; T156-N158 PolarHBondContact O-N 3.18Å; N158-G160 VanDerWaalsContact C-N 3.29Å; N158-F161 WeakPolarHBondContact O-CB 3.3Å; N158-F161 PolarHBondContact O-N 3.33Å; N158-F161 WeakPolarHBondContact OD1-CD2 3.35Å; N158-L162 PolarHBondContact O-N 3.38Å; N158-Q362 PolarHBondContact ND2-NE2 3.43Å; N158-Q362 PolarHBondContact ND2-OE1 2.75Å; N158-G477 VanDerWaalsContact ND2-C 3.27Å; N158-G477 PolarHBondContact ND2-O 3.38Å; N158-I478 HydrophobicContact CB-CB 4.5Å; N158-I478 HydrophobicContact CB-CG1 3.6Å
159V96.1Very high91.8Very high59 Ų5923.5 Ų23.536%0.35814%0.138SC..Hα-helixtrans-59.6-44.1166.4173.10000110.2A155 T156 F161 L162 V163 T209 I478A155-V159 WeakPolarHBondContact O-CG2 3.48Å; A155-V159 PolarHBondContact O-N 2.81Å; T156-V159 PolarHBondContact O-N 3.08Å; V159-F161 VanDerWaalsContact C-N 3.35Å; V159-F161 PolarHBondContact O-N 3.35Å; V159-L162 WeakPolarHBondContact O-CB 3.42Å; V159-L162 PolarHBondContact O-N 2.57Å; V159-V163 WeakPolarHBondContact O-CG2 3.27Å; V159-V163 PolarHBondContact O-N 3.38Å; V159-V163 VanDerWaalsContact O-N 3.11Å; V159-T209 HydrophobicContact CG1-CG2 4.49Å; V159-I478 HydrophobicContact CB-CD1 4.43Å; V159-I478 HydrophobicContact CG2-CD1 3.61Å; V159-I478 HydrophobicContact CG2-CG1 3.97Å
160G95.6Very high91.4Very high1 Ų129 Ų291%0.0116%0.158CC..Hα-helixtrans-55-48.7171.200000111.9T156 L157 N158 L162 V163 G164 T209 F213T156-G160 PolarHBondContact O-N 3.21Å; L157-G160 CarbonylContact O-C 3.58Å; L157-G160 WeakPolarHBondContact O-CA 3.2Å; L157-G160 PolarHBondContact O-N 3.26Å; L157-G160 VanDerWaalsContact O-N 3.1Å; N158-G160 VanDerWaalsContact C-N 3.29Å; G160-L162 PolarHBondContact O-N 3.44Å; G160-V163 PolarHBondContact O-N 3.16Å; G160-G164 WeakPolarHBondContact O-CA 3.47Å; G160-G164 PolarHBondContact O-N 3.22Å; G160-T209 WeakPolarHBondContact CA-O 3.31Å; G160-F213 WeakPolarHBondContact O-CA 3.42Å; G160-F213 PolarHBondContact O-N 3.4Å
161F93.9Very high91.1Very high5 Ų530 Ų302%0.02216%0.163CC..Hα-helixtrans-57.2-46.7177.1-70.5-4.8000112.7F32 Y36 L157 N158 V159 V163 G164 S165 G212 V215 K216F32-F161 HydrophobicContact CE2-CE1 4.47Å; F32-F161 HydrophobicContact CE2-CE2 4.39Å; F32-F161 AromaticContact CE2-CZ 3.79Å; F32-F161 HydrophobicContact CE2-CZ 3.79Å; F32-F161 HydrophobicContact CZ-CZ 4.43Å; Y36-F161 AromaticContact CD2-CE2 3.54Å; Y36-F161 HydrophobicContact CD2-CE2 3.54Å; Y36-F161 HydrophobicContact CD2-CZ 4.04Å; Y36-F161 AromaticContact CE2-CE2 3.82Å; Y36-F161 HydrophobicContact CE2-CE2 3.82Å; L157-F161 HydrophobicContact CD1-CE1 4.17Å; L157-F161 HydrophobicContact CD1-CZ 4.47Å; L157-F161 HydrophobicContact CD2-CE1 4.4Å; L157-F161 HydrophobicContact CD2-CE2 4.37Å; L157-F161 HydrophobicContact CD2-CZ 3.9Å; L157-F161 HydrophobicContact CG-CE1 4.01Å; L157-F161 HydrophobicContact CG-CZ 3.98Å; L157-F161 PolarHBondContact O-N 3.38Å; N158-F161 WeakPolarHBondContact O-CB 3.3Å; N158-F161 PolarHBondContact O-N 3.33Å; N158-F161 WeakPolarHBondContact OD1-CD2 3.35Å; V159-F161 VanDerWaalsContact C-N 3.35Å; V159-F161 PolarHBondContact O-N 3.35Å; F161-V163 PolarHBondContact O-N 3.28Å; F161-G164 PolarHBondContact O-N 3.45Å; F161-S165 WeakPolarHBondContact O-CB 3.46Å; F161-S165 PolarHBondContact O-N 3.25Å; F161-G212 WeakPolarHBondContact CD1-O 3.36Å; F161-G212 WeakPolarHBondContact CE1-O 3.37Å; F161-V215 HydrophobicContact CE1-CB 4.13Å; F161-V215 HydrophobicContact CE1-CG1 3.88Å; F161-V215 HydrophobicContact CZ-CG1 4.23Å; F161-K216 HydrophobicContact CB-CB 4.06Å; F161-K216 HydrophobicContact CB-CD 4.08Å; F161-K216 HydrophobicContact CB-CG 4.16Å; F161-K216 HydrophobicContact CD1-CB 3.73Å; F161-K216 HydrophobicContact CE1-CB 4.43Å; F161-K216 HydrophobicContact CG-CB 4.07Å; F161-K216 HydrophobicContact CG-CD 4.22Å; F161-K216 HydrophobicContact CG-CG 4.5Å; F161-K216 WeakPolarHBondContact O-CG 3.14Å
162L92.6Very high90.8Very high37 Ų3730.1 Ų30.119%0.19416%0.164CC..Hα-helixtrans-56.3-53.2178.8175.559.4000111.4N158 V159 G160 G164 S165 T471 D474 I475N158-L162 PolarHBondContact O-N 3.38Å; V159-L162 WeakPolarHBondContact O-CB 3.42Å; V159-L162 PolarHBondContact O-N 2.57Å; G160-L162 PolarHBondContact O-N 3.44Å; L162-G164 VanDerWaalsContact C-N 3.34Å; L162-G164 PolarHBondContact O-N 3.17Å; L162-S165 PolarHBondContact O-N 3.37Å; L162-S165 PolarHBondContact O-OG 3.31Å; L162-T471 HydrophobicContact CD1-CG2 3.33Å; L162-D474 HydrophobicContact CB-CB 3.9Å; L162-D474 HydrophobicContact CD1-CB 4.29Å; L162-I475 HydrophobicContact CD2-CG1 4.49Å
163V92.9Very high90.3Very high71 Ų7131.5 Ų31.543%0.4317%0.173SC..Hα-helixtrans-67.6-37.7-179.9-179.10000111.3V159 G160 F161 T167 F213V159-V163 WeakPolarHBondContact O-CG2 3.27Å; V159-V163 PolarHBondContact O-N 3.38Å; V159-V163 VanDerWaalsContact O-N 3.11Å; G160-V163 PolarHBondContact O-N 3.16Å; F161-V163 PolarHBondContact O-N 3.28Å; V163-T167 WeakPolarHBondContact O-CB 3.44Å; V163-T167 PolarHBondContact O-N 3.5Å; V163-T167 VanDerWaalsContact O-N 3.07Å; V163-T167 PolarHBondContact O-OG1 2.98Å; V163-F213 HydrophobicContact CB-CD2 4.26Å; V163-F213 HydrophobicContact CG1-CD2 3.96Å; V163-F213 HydrophobicContact CG1-CE2 4.08Å
164G91.2Very high89.8Confident0 Ų038.6 Ų38.60%020%0.2CC..Hα-helixtrans-64-39.8179.200000112.2G160 F161 L162 T167 F168 F213G160-G164 WeakPolarHBondContact O-CA 3.47Å; G160-G164 PolarHBondContact O-N 3.22Å; F161-G164 PolarHBondContact O-N 3.45Å; L162-G164 VanDerWaalsContact C-N 3.34Å; L162-G164 PolarHBondContact O-N 3.17Å; G164-T167 PolarHBondContact O-N 3.48Å; G164-F168 WeakPolarHBondContact O-CB 3.18Å; G164-F168 PolarHBondContact O-N 3.33Å; G164-F213 WeakPolarHBondContact CA-O 3.4Å
165S86.4Confident89.4Confident6 Ų643.2 Ų43.24%0.04222%0.22CC..Hα-helixtrans-60.6-49.917971.70000111.7F161 L162 T167 G169 M220F161-S165 WeakPolarHBondContact O-CB 3.46Å; F161-S165 PolarHBondContact O-N 3.25Å; L162-S165 PolarHBondContact O-N 3.37Å; L162-S165 PolarHBondContact O-OG 3.31Å; S165-T167 PolarHBondContact O-N 3.4Å; S165-G169 PolarHBondContact O-N 3.29Å; S165-M220 VanDerWaalsContact CA-CE 3.41Å; S165-M220 WeakPolarHBondContact O-CE 3.35Å
166I85.6Confident89Confident105 Ų10543 Ų4354%0.53822%0.218SC..Hα-helixtrans-64.1-46.3-180-61.3168000110.5Y170I166-Y170 PolarHBondContact O-N 3.31Å
167T88.9Confident88.7Confident51 Ų5142.5 Ų42.531%0.31321%0.213SC..Hα-helixtrans-71.4-49.2-173.4-50.70000112.2V163 G164 S165 G169 Y170 L171 F213V163-T167 WeakPolarHBondContact O-CB 3.44Å; V163-T167 PolarHBondContact O-N 3.5Å; V163-T167 VanDerWaalsContact O-N 3.07Å; V163-T167 PolarHBondContact O-OG1 2.98Å; G164-T167 PolarHBondContact O-N 3.48Å; S165-T167 PolarHBondContact O-N 3.4Å; T167-G169 VanDerWaalsContact C-N 3.34Å; T167-Y170 PolarHBondContact O-N 3.32Å; T167-L171 HydrophobicContact CG2-CD1 3.93Å; T167-L171 HydrophobicContact CG2-CG 4.45Å; T167-L171 VanDerWaalsContact O-CG 3.3Å; T167-L171 WeakPolarHBondContact O-CG 3.21Å; T167-L171 PolarHBondContact O-N 2.87Å; T167-F213 HydrophobicContact CG2-CE2 3.93Å; T167-F213 HydrophobicContact CG2-CZ 3.79Å
168F85.7Confident88.6Confident2 Ų244.2 Ų44.21%0.00922%0.221CC..Hα-helixtrans-74.9-23.4-178.7-82.5-85000113.1G164 L171 A172 S180 M183 F213 G217G164-F168 WeakPolarHBondContact O-CB 3.18Å; G164-F168 PolarHBondContact O-N 3.33Å; F168-L171 HydrophobicContact CD1-CD1 4.05Å; F168-L171 HydrophobicContact CE1-CD1 4.24Å; F168-L171 HydrophobicContact CG-CD1 4.34Å; F168-L171 PolarHBondContact O-N 3.28Å; F168-A172 WeakPolarHBondContact O-CB 3.37Å; F168-A172 PolarHBondContact O-N 3.11Å; F168-S180 WeakPolarHBondContact CD1-OG 3.45Å; F168-M183 HydrophobicContact CE1-CE 3.95Å; F168-M183 HydrophobicContact CZ-CE 4.38Å; F168-F213 HydrophobicContact CD2-CE1 4.14Å; F168-F213 HydrophobicContact CD2-CE2 4.44Å; F168-F213 HydrophobicContact CD2-CZ 4.03Å; F168-F213 AromaticContact CE2-CD1 3.78Å; F168-F213 HydrophobicContact CE2-CD1 3.78Å; F168-F213 AromaticContact CE2-CE1 3.32Å; F168-F213 HydrophobicContact CE2-CE1 3.32Å; F168-F213 HydrophobicContact CE2-CE2 4.38Å; F168-F213 HydrophobicContact CE2-CG 4.47Å; F168-F213 AromaticContact CE2-CZ 3.66Å; F168-F213 HydrophobicContact CE2-CZ 3.66Å; F168-F213 HydrophobicContact CZ-CE1 4.05Å; F168-G217 VanDerWaalsContact CG-CA 3.41Å
169G80.8Confident88.4Confident25 Ų2552 Ų5226%0.25825%0.25SS..Hα-helixtrans-57.7-52.8166.300000110.8S165 T167 L171 A172 D173S165-G169 PolarHBondContact O-N 3.29Å; T167-G169 VanDerWaalsContact C-N 3.34Å; G169-L171 PolarHBondContact O-N 3.07Å; G169-A172 PolarHBondContact O-N 2.76Å; G169-D173 PolarHBondContact O-N 2.98Å; G169-D173 VanDerWaalsContact O-N 3.16Å
170Y83.4Confident88.2Confident136 Ų13649.4 Ų49.453%0.53323%0.234SC..Hα-helixtrans-61-43.8176.1179.9-99000113.2I166 T167 D173 R174I166-Y170 PolarHBondContact O-N 3.31Å; T167-Y170 PolarHBondContact O-N 3.32Å; Y170-D173 PolarHBondContact O-N 3.36Å; Y170-R174 HydrophobicContact CE1-CB 4.46Å; Y170-R174 WeakPolarHBondContact O-CB 3.35Å; Y170-R174 PolarHBondContact O-N 3.48Å; Y170-R174 WeakPolarHBondContact OH-CD 3.3Å; Y170-R174 PolarHBondContact OH-NH1 3.49Å
171L85.1Confident88.1Confident29 Ų2949.5 Ų49.515%0.15223%0.234CC..Hα-helixtrans-65.5-39.3179.4-68.5167.6000112.4T167 F168 G169 D173 R174 F175 M183T167-L171 HydrophobicContact CG2-CD1 3.93Å; T167-L171 HydrophobicContact CG2-CG 4.45Å; T167-L171 VanDerWaalsContact O-CG 3.3Å; T167-L171 WeakPolarHBondContact O-CG 3.21Å; T167-L171 PolarHBondContact O-N 2.87Å; F168-L171 HydrophobicContact CD1-CD1 4.05Å; F168-L171 HydrophobicContact CE1-CD1 4.24Å; F168-L171 HydrophobicContact CG-CD1 4.34Å; F168-L171 PolarHBondContact O-N 3.28Å; G169-L171 PolarHBondContact O-N 3.07Å; L171-D173 VanDerWaalsContact C-N 3.31Å; L171-D173 PolarHBondContact O-N 2.58Å; L171-R174 PolarHBondContact O-N 3.03Å; L171-F175 HydrophobicContact CB-CD2 4.44Å; L171-F175 HydrophobicContact CD2-CD2 3.59Å; L171-F175 HydrophobicContact CD2-CE2 3.55Å; L171-F175 WeakPolarHBondContact O-CB 3.42Å; L171-F175 PolarHBondContact O-N 3.04Å; L171-M183 HydrophobicContact CD1-CE 3.57Å
172A85.1Confident88.2Confident7 Ų750.4 Ų50.46%0.05824%0.239CC..Hα-helixtrans-65.6-35177.900000112.1F168 G169 G176 R177F168-A172 WeakPolarHBondContact O-CB 3.37Å; F168-A172 PolarHBondContact O-N 3.11Å; G169-A172 PolarHBondContact O-N 2.76Å; A172-G176 CarbonylContact O-C 3.44Å; A172-G176 VanDerWaalsContact O-C 3.27Å; A172-G176 VanDerWaalsContact O-CA 3.3Å; A172-G176 WeakPolarHBondContact O-CA 3.47Å; A172-G176 PolarHBondContact O-N 3.31Å; A172-R177 PolarHBondContact O-NE 3.33Å
173D83.2Confident88.3Confident91 Ų9153.2 Ų53.249%0.48725%0.253SS..Hα-helixtrans-76.7-35.6176.5-70.6-18.4000112.5G169 Y170 L171 R177 W290 Q294G169-D173 PolarHBondContact O-N 2.98Å; G169-D173 VanDerWaalsContact O-N 3.16Å; Y170-D173 PolarHBondContact O-N 3.36Å; L171-D173 VanDerWaalsContact C-N 3.31Å; L171-D173 PolarHBondContact O-N 2.58Å; D173-R177 IonicContact OD1-CZ 3.49Å; D173-R177 IonicContact OD1-NE 2.65Å; D173-R177 IonicContact OD1-NH2 3.97Å; D173-R177 PolarHBondContact OD1-NH2 3.41Å; D173-W290 PolarHBondContact O-NE1 3.45Å; D173-Q294 PolarHBondContact O-NE2 2.93Å
174R83.5Confident88.3Confident148 Ų14849.9 Ų49.956%0.55823%0.232SC*.Hα-helixtrans-83.2-43.9-178.6-174.9167.7-175.8166.10.4114.1Y170 L171Y170-R174 HydrophobicContact CE1-CB 4.46Å; Y170-R174 WeakPolarHBondContact O-CB 3.35Å; Y170-R174 PolarHBondContact O-N 3.48Å; Y170-R174 WeakPolarHBondContact OH-CD 3.3Å; Y170-R174 PolarHBondContact OH-NH1 3.49Å; L171-R174 PolarHBondContact O-N 3.03Å
175F86.7Confident88.5Confident99 Ų9949.9 Ų49.943%0.43423%0.232SC..Hα-helixtrans-106.4-9.7-171.7-65-70.5000113.9L171 R179 W290L171-F175 HydrophobicContact CB-CD2 4.44Å; L171-F175 HydrophobicContact CD2-CD2 3.59Å; L171-F175 HydrophobicContact CD2-CE2 3.55Å; L171-F175 WeakPolarHBondContact O-CB 3.42Å; L171-F175 PolarHBondContact O-N 3.04Å; F175-R179 WeakPolarHBondContact O-CD 3.38Å; F175-W290 VanDerWaalsContact C-CZ2 3.48Å
176G86.8Confident89Confident0 Ų053.7 Ų53.70%025%0.252CS..  trans102.9154.3-178.800000112.7A172 S180 W290A172-G176 CarbonylContact O-C 3.44Å; A172-G176 VanDerWaalsContact O-C 3.27Å; A172-G176 VanDerWaalsContact O-CA 3.3Å; A172-G176 WeakPolarHBondContact O-CA 3.47Å; A172-G176 PolarHBondContact O-N 3.31Å; G176-S180 VanDerWaalsContact O-CB 3.22Å; G176-S180 WeakPolarHBondContact O-CB 3.23Å; G176-S180 PolarHBondContact O-N 3.46Å; G176-S180 VanDerWaalsContact O-N 3.09Å; G176-W290 VanDerWaalsContact CA-CZ2 3.47Å
177R89.5Confident89.5Confident17 Ų1751.4 Ų51.46%0.06424%0.24CC..Hα-helixtrans-72.8-41.3-171-69.881.1-151.6-130.43110.5A172 D173 F181 V224 L225 E228 E286A172-R177 PolarHBondContact O-NE 3.33Å; D173-R177 IonicContact OD1-CZ 3.49Å; D173-R177 IonicContact OD1-NE 2.65Å; D173-R177 IonicContact OD1-NH2 3.97Å; D173-R177 PolarHBondContact OD1-NH2 3.41Å; R177-F181 VanDerWaalsContact O-CB 3.28Å; R177-F181 WeakPolarHBondContact O-CB 3.16Å; R177-F181 PolarHBondContact O-N 3.49Å; R177-V224 HydrophobicContact CG-CG1 4.12Å; R177-L225 HydrophobicContact CB-CB 4.19Å; R177-L225 HydrophobicContact CB-CD1 4.24Å; R177-E228 IonicContact CZ-OE1 2.64Å; R177-E228 IonicContact CZ-OE2 3.87Å; R177-E228 IonicContact NE-OE2 3.77Å; R177-E228 IonicContact NH1-OE1 2.64Å; R177-E228 PolarHBondContact NH1-OE1 3.47Å; R177-E228 IonicContact NH1-OE2 3.25Å; R177-E228 PolarHBondContact NH1-OE2 2.88Å; R177-E286 PolarHBondContact N-OE1 3.38Å
178K91.8Very high89.8Confident36 Ų3649 Ų4916%0.15723%0.226CC..Hα-helixtrans-65.1-44.1177.3-179.9-178.5174.4170.60112.6F181 L182 F281 I284 E286K178-F181 PolarHBondContact O-N 2.85Å; K178-L182 HydrophobicContact CG-CD1 4.15Å; K178-L182 VanDerWaalsContact O-CG 3.31Å; K178-L182 WeakPolarHBondContact O-CG 3.28Å; K178-L182 PolarHBondContact O-N 3.26Å; K178-F281 WeakPolarHBondContact CE-O 3.34Å; K178-F281 PolarHBondContact NZ-O 3.49Å; K178-I284 WeakPolarHBondContact CD-O 3.48Å; K178-I284 WeakPolarHBondContact CE-O 3.48Å; K178-I284 PolarHBondContact NZ-O 3.49Å; K178-E286 VanDerWaalsContact CB-OE2 3.26Å; K178-E286 WeakPolarHBondContact CB-OE2 3.41Å; K178-E286 PolarHBondContact N-OE1 3.25Å; K178-E286 PolarHBondContact N-OE2 3.15Å
179R91.7Very high90.3Very high168 Ų16849 Ų4963%0.63423%0.225SC*.Hα-helixtrans-67.3-44179.1-71-174.1179.4170.1-3.4111.8F175 F181 L182 M183F175-R179 WeakPolarHBondContact O-CD 3.38Å; R179-F181 VanDerWaalsContact C-N 3.33Å; R179-F181 PolarHBondContact O-N 3.15Å; R179-L182 PolarHBondContact O-N 3.18Å; R179-M183 WeakPolarHBondContact O-CB 3.29Å; R179-M183 PolarHBondContact O-N 3.4Å
180S92.4Very high91.1Very high3 Ų350.8 Ų50.82%0.02123%0.231CC..Hα-helixtrans-56.6-47.9174.5-172.90000111.4F168 G176 L182 M183 S184 S221F168-S180 WeakPolarHBondContact CD1-OG 3.45Å; G176-S180 VanDerWaalsContact O-CB 3.22Å; G176-S180 WeakPolarHBondContact O-CB 3.23Å; G176-S180 PolarHBondContact O-N 3.46Å; G176-S180 VanDerWaalsContact O-N 3.09Å; S180-L182 PolarHBondContact O-N 3.18Å; S180-M183 PolarHBondContact O-N 3.06Å; S180-S184 WeakPolarHBondContact O-CB 3.39Å; S180-S184 PolarHBondContact O-N 2.92Å; S180-S184 PolarHBondContact O-OG 3.23Å; S180-S221 PolarHBondContact OG-OG 2.97Å; S180-S221 VanDerWaalsContact OG-OG 3.12Å
181F93.7Very high91.8Very high4 Ų444.4 Ų44.42%0.01821%0.207CC..Hα-helixtrans-55.2-52.2173.5170.8-104.7000112.3L25 V28 R177 K178 R179 M183 S184 N185 V222 F277 Y280L25-F181 HydrophobicContact CD2-CZ 4.34Å; V28-F181 HydrophobicContact CG1-CE2 4.08Å; V28-F181 HydrophobicContact CG2-CE2 3.86Å; V28-F181 HydrophobicContact CG2-CZ 3.74Å; R177-F181 VanDerWaalsContact O-CB 3.28Å; R177-F181 WeakPolarHBondContact O-CB 3.16Å; R177-F181 PolarHBondContact O-N 3.49Å; K178-F181 PolarHBondContact O-N 2.85Å; R179-F181 VanDerWaalsContact C-N 3.33Å; R179-F181 PolarHBondContact O-N 3.15Å; F181-M183 PolarHBondContact O-N 3.4Å; F181-S184 PolarHBondContact O-N 3.15Å; F181-S184 PolarHBondContact O-OG 3.23Å; F181-N185 WeakPolarHBondContact CD2-ND2 3.25Å; F181-N185 WeakPolarHBondContact CE2-ND2 3.49Å; F181-N185 WeakPolarHBondContact CZ-ND2 3.4Å; F181-N185 PolarHBondContact O-N 3.09Å; F181-N185 PolarHBondContact O-ND2 3.49Å; F181-V222 HydrophobicContact CD2-CG2 3.31Å; F181-V222 HydrophobicContact CE2-CG2 3.21Å; F181-V222 HydrophobicContact CG-CG2 4.42Å; F181-V222 HydrophobicContact CZ-CG2 4.29Å; F181-F277 HydrophobicContact CZ-CB 4.35Å; F181-Y280 HydrophobicContact CE1-CD2 4.17Å; F181-Y280 HydrophobicContact CZ-CD2 4.17Å
182L94.5Very high92.3Very high24 Ų2443 Ų4313%0.12620%0.2CC..Hα-helixtrans-64.8-40.8-177.5-67.9165.5000112.9K178 R179 S180 S184 N185 L186 L278 F281K178-L182 HydrophobicContact CG-CD1 4.15Å; K178-L182 VanDerWaalsContact O-CG 3.31Å; K178-L182 WeakPolarHBondContact O-CG 3.28Å; K178-L182 PolarHBondContact O-N 3.26Å; R179-L182 PolarHBondContact O-N 3.18Å; S180-L182 PolarHBondContact O-N 3.18Å; L182-S184 VanDerWaalsContact C-N 3.3Å; L182-S184 PolarHBondContact O-N 3.38Å; L182-N185 PolarHBondContact O-N 3.28Å; L182-L186 PolarHBondContact O-N 3.26Å; L182-L278 HydrophobicContact CD2-CD2 4.44Å; L182-L278 WeakPolarHBondContact O-CD2 3.39Å; L182-F281 HydrophobicContact CD1-CB 3.71Å; L182-F281 HydrophobicContact CD1-CD2 3.48Å; L182-F281 VanDerWaalsContact CD1-CD2 3.48Å; L182-F281 HydrophobicContact CD1-CG 4.07Å; L182-F281 HydrophobicContact CD2-CB 4.19Å
183M94.5Very high92.9Very high96 Ų9645.8 Ų45.847%0.47321%0.213SC..Hα-helixtrans-62.4-40.9176.4-169.31737600111.3F168 L171 R179 S180 F181 L186 L187F168-M183 HydrophobicContact CE1-CE 3.95Å; F168-M183 HydrophobicContact CZ-CE 4.38Å; L171-M183 HydrophobicContact CD1-CE 3.57Å; R179-M183 WeakPolarHBondContact O-CB 3.29Å; R179-M183 PolarHBondContact O-N 3.4Å; S180-M183 PolarHBondContact O-N 3.06Å; F181-M183 PolarHBondContact O-N 3.4Å; M183-L186 PolarHBondContact O-N 3.45Å; M183-L187 WeakPolarHBondContact O-CB 3.5Å; M183-L187 PolarHBondContact O-N 2.78Å
184S95Very high93.6Very high0 Ų044.8 Ų44.80%021%0.207CC..Hα-helixtrans-63.7-41.5175.777.20000112.4S180 F181 L182 L187 N188 A214 G218S180-S184 WeakPolarHBondContact O-CB 3.39Å; S180-S184 PolarHBondContact O-N 2.92Å; S180-S184 PolarHBondContact O-OG 3.23Å; F181-S184 PolarHBondContact O-N 3.15Å; F181-S184 PolarHBondContact O-OG 3.23Å; L182-S184 VanDerWaalsContact C-N 3.3Å; L182-S184 PolarHBondContact O-N 3.38Å; S184-L187 PolarHBondContact O-N 2.91Å; S184-N188 WeakPolarHBondContact O-CB 3.34Å; S184-N188 PolarHBondContact O-N 2.99Å; S184-N188 PolarHBondContact O-ND2 3.07Å; S184-N188 VanDerWaalsContact O-ND2 3.08Å; S184-A214 WeakPolarHBondContact CB-O 3.48Å; S184-G218 WeakPolarHBondContact OG-CA 3.44Å; S184-G218 PolarHBondContact OG-N 3Å
185N95.1Very high94.2Very high0 Ų037.7 Ų37.70%018%0.18CC..Hα-helixtrans-66.6-40.1178.2-77.9-85.2000112.3F181 L182 L187 N188 G189 Y274 F277 L278F181-N185 WeakPolarHBondContact CD2-ND2 3.25Å; F181-N185 WeakPolarHBondContact CE2-ND2 3.49Å; F181-N185 WeakPolarHBondContact CZ-ND2 3.4Å; F181-N185 PolarHBondContact O-N 3.09Å; F181-N185 PolarHBondContact O-ND2 3.49Å; L182-N185 PolarHBondContact O-N 3.28Å; N185-L187 VanDerWaalsContact C-N 3.34Å; N185-N188 WeakPolarHBondContact O-CB 3.44Å; N185-N188 PolarHBondContact O-N 3.43Å; N185-G189 PolarHBondContact O-N 2.92Å; N185-Y274 WeakPolarHBondContact OD1-CD1 2.95Å; N185-F277 WeakPolarHBondContact OD1-CD2 3.49Å; N185-L278 HydrophobicContact CB-CD2 4.02Å
186L96.2Very high94.7Very high87 Ų8733.2 Ų33.246%0.45516%0.161SC..Hα-helixtrans-61.2-47.3175.117962.7000110.5L182 M183 N188 G189 V190 F275 L278L182-L186 PolarHBondContact O-N 3.26Å; M183-L186 PolarHBondContact O-N 3.45Å; L186-N188 VanDerWaalsContact C-N 3.31Å; L186-N188 PolarHBondContact O-N 3.2Å; L186-G189 PolarHBondContact O-N 2.63Å; L186-V190 HydrophobicContact CD1-CG2 4.38Å; L186-V190 WeakPolarHBondContact O-CG2 3.33Å; L186-V190 PolarHBondContact O-N 3.41Å; L186-F275 HydrophobicContact CD1-CE1 4.37Å; L186-L278 HydrophobicContact CB-CD2 4.03Å; L186-L278 HydrophobicContact CD1-CD1 4Å
187L96.6Very high95.1Very high56 Ų5638 Ų3829%0.29319%0.19SC..Hα-helixtrans-64.8-36.3178.2-171.458.5000111.7M183 S184 N185 A191 I210 F213 A214M183-L187 WeakPolarHBondContact O-CB 3.5Å; M183-L187 PolarHBondContact O-N 2.78Å; S184-L187 PolarHBondContact O-N 2.91Å; N185-L187 VanDerWaalsContact C-N 3.34Å; L187-A191 WeakPolarHBondContact O-CB 3.46Å; L187-A191 PolarHBondContact O-N 3.29Å; L187-I210 HydrophobicContact CD1-CG2 3.82Å; L187-I210 HydrophobicContact CD2-CG2 4.33Å; L187-I210 HydrophobicContact CG-CG2 4.08Å; L187-F213 HydrophobicContact CD2-CD1 3.75Å; L187-F213 HydrophobicContact CD2-CE1 3.81Å; L187-A214 HydrophobicContact CB-CB 3.75Å; L187-A214 HydrophobicContact CD2-CB 3.82Å; L187-A214 HydrophobicContact CG-CB 3.67Å
188N95.3Very high95.5Very high2 Ų237.2 Ų37.21%0.01119%0.187CC..Hα-helixtrans-61.3-50.3174.1-79.6-34.1000112.6S184 N185 L186 V190 G192 F211 A214 V215 Y274S184-N188 WeakPolarHBondContact O-CB 3.34Å; S184-N188 PolarHBondContact O-N 2.99Å; S184-N188 PolarHBondContact O-ND2 3.07Å; S184-N188 VanDerWaalsContact O-ND2 3.08Å; N185-N188 WeakPolarHBondContact O-CB 3.44Å; N185-N188 PolarHBondContact O-N 3.43Å; L186-N188 VanDerWaalsContact C-N 3.31Å; L186-N188 PolarHBondContact O-N 3.2Å; N188-V190 PolarHBondContact O-N 3.05Å; N188-G192 WeakPolarHBondContact O-CA 3.2Å; N188-G192 PolarHBondContact O-N 3.43Å; N188-F211 HydrophobicContact CB-CD2 4.31Å; N188-F211 HydrophobicContact CB-CE2 3.99Å; N188-F211 WeakPolarHBondContact O-CD2 3.24Å; N188-F211 VanDerWaalsContact O-CE2 3.27Å; N188-F211 WeakPolarHBondContact O-CE2 3.47Å; N188-F211 PolarHBondContact OD1-O 3.18Å; N188-A214 HydrophobicContact CB-CB 4.44Å; N188-A214 PolarHBondContact ND2-O 3.37Å; N188-A214 WeakPolarHBondContact OD1-CB 3.3Å; N188-V215 WeakPolarHBondContact ND2-CA 3.21Å; N188-V215 VanDerWaalsContact OD1-CA 3.31Å; N188-V215 WeakPolarHBondContact OD1-CA 3.39Å; N188-V215 WeakPolarHBondContact OD1-CG2 3.1Å; N188-V215 PolarHBondContact OD1-N 3.02Å; N188-Y274 HydrophobicContact CB-CD1 3.83Å; N188-Y274 HydrophobicContact CB-CD2 3.94Å; N188-Y274 HydrophobicContact CB-CE1 4.23Å; N188-Y274 HydrophobicContact CB-CE2 4.33Å; N188-Y274 HydrophobicContact CB-CG 3.68Å
189G96.4Very high95.5Very high0 Ų040.3 Ų40.30%021%0.211CC..Hα-helixtrans-60.7-45.7178.900000111.7N185 L186 I193 F275N185-G189 PolarHBondContact O-N 2.92Å; L186-G189 PolarHBondContact O-N 2.63Å; G189-I193 WeakPolarHBondContact O-CG1 3.2Å; G189-I193 PolarHBondContact O-N 3.4Å; G189-I193 VanDerWaalsContact O-N 3.15Å; G189-F275 VanDerWaalsContact C-CE2 3.49Å; G189-F275 VanDerWaalsContact CA-CE2 3.41Å
190V97.5Very high95.7Very high64 Ų6435.9 Ų35.939%0.38820%0.2SC..Hα-helixtrans-66.6-52.1179.6174.40000111.4L186 N188 G192 I193 L194 F275L186-V190 HydrophobicContact CD1-CG2 4.38Å; L186-V190 WeakPolarHBondContact O-CG2 3.33Å; L186-V190 PolarHBondContact O-N 3.41Å; N188-V190 PolarHBondContact O-N 3.05Å; V190-G192 VanDerWaalsContact C-N 3.31Å; V190-G192 PolarHBondContact O-N 3.37Å; V190-I193 PolarHBondContact O-N 3.37Å; V190-L194 HydrophobicContact CG1-CD1 3.99Å; V190-L194 HydrophobicContact CG1-CG 4.46Å; V190-L194 WeakPolarHBondContact O-CG 3.05Å; V190-L194 PolarHBondContact O-N 2.96Å; V190-F275 HydrophobicContact CG2-CE1 4.32Å; V190-F275 HydrophobicContact CG2-CZ 4.3Å
191A97.3Very high95.8Very high2 Ų236.5 Ų36.52%0.01720%0.202CC..Hα-helixtrans-63.2-38.5-179.700000111.8L187 I193 L194 V195 I210 F211L187-A191 WeakPolarHBondContact O-CB 3.46Å; L187-A191 PolarHBondContact O-N 3.29Å; A191-I193 PolarHBondContact O-N 3.36Å; A191-L194 PolarHBondContact O-N 3.24Å; A191-V195 WeakPolarHBondContact O-CG2 3.36Å; A191-V195 PolarHBondContact O-N 3.48Å; A191-I210 HydrophobicContact CB-CB 4.25Å; A191-I210 HydrophobicContact CB-CG2 3.83Å; A191-F211 HydrophobicContact CB-CB 3.9Å; A191-F211 HydrophobicContact CB-CD2 4.4Å; A191-F211 HydrophobicContact CB-CG 4.48Å
192G96.4Very high95.8Very high0 Ų041.9 Ų41.90%023%0.23CC..Hα-helixtrans-61.2-43176.300000113.1N188 V190 V195 A196 Q267N188-G192 WeakPolarHBondContact O-CA 3.2Å; N188-G192 PolarHBondContact O-N 3.43Å; V190-G192 VanDerWaalsContact C-N 3.31Å; V190-G192 PolarHBondContact O-N 3.37Å; G192-V195 PolarHBondContact O-N 3.22Å; G192-A196 PolarHBondContact O-N 3.37Å; G192-Q267 WeakPolarHBondContact O-CG 3.43Å; G192-Q267 PolarHBondContact O-NE2 2.95Å
193I97.6Very high95.9Very high64 Ų6442.4 Ų42.433%0.32824%0.236SC..Hα-helixtrans-66.5-41.3173.5-68.1172.8000110.9G189 V190 A191 V195 A196 V197 A271 F275G189-I193 WeakPolarHBondContact O-CG1 3.2Å; G189-I193 PolarHBondContact O-N 3.4Å; G189-I193 VanDerWaalsContact O-N 3.15Å; V190-I193 PolarHBondContact O-N 3.37Å; A191-I193 PolarHBondContact O-N 3.36Å; I193-V195 VanDerWaalsContact C-N 3.29Å; I193-V195 PolarHBondContact O-N 2.95Å; I193-A196 WeakPolarHBondContact O-CB 3.48Å; I193-A196 PolarHBondContact O-N 2.84Å; I193-V197 HydrophobicContact CG2-CG2 4.3Å; I193-V197 WeakPolarHBondContact O-CG2 3.38Å; I193-V197 PolarHBondContact O-N 3.26Å; I193-A271 HydrophobicContact CG1-CB 4.14Å; I193-F275 HydrophobicContact CD1-CE2 3.5Å; I193-F275 HydrophobicContact CD1-CZ 3.84Å; I193-F275 HydrophobicContact CG1-CE2 4.36Å
194L97.5Very high96Very high70 Ų7037.9 Ų37.937%0.36621%0.213SC..Hα-helixtrans-61.7-36.7177.7-71.3173000112.3V190 A191 A196 V197 A198 F207V190-L194 HydrophobicContact CG1-CD1 3.99Å; V190-L194 HydrophobicContact CG1-CG 4.46Å; V190-L194 WeakPolarHBondContact O-CG 3.05Å; V190-L194 PolarHBondContact O-N 2.96Å; A191-L194 PolarHBondContact O-N 3.24Å; L194-A196 VanDerWaalsContact C-N 3.34Å; L194-V197 PolarHBondContact O-N 3.42Å; L194-A198 PolarHBondContact O-N 2.94Å; L194-F207 HydrophobicContact CB-CB 4.12Å; L194-F207 HydrophobicContact CB-CD1 3.91Å; L194-F207 HydrophobicContact CB-CD2 3.73Å; L194-F207 HydrophobicContact CB-CE1 4.23Å; L194-F207 HydrophobicContact CB-CE2 4.05Å; L194-F207 HydrophobicContact CB-CG 3.66Å; L194-F207 HydrophobicContact CB-CZ 4.3Å; L194-F207 HydrophobicContact CD1-CD1 4.03Å; L194-F207 HydrophobicContact CD1-CE1 3.99Å; L194-F207 HydrophobicContact CD2-CZ 4.41Å; L194-F207 VanDerWaalsContact O-CD2 3.26Å; L194-F207 WeakPolarHBondContact O-CD2 3.38Å
195V96.9Very high96.1Very high0 Ų038.7 Ų38.70%022%0.217CC..Hα-helixtrans-59.9-44.9170.7173.40000110.6A191 G192 I193 V197 A198 M204 F207 R208 Q267A191-V195 WeakPolarHBondContact O-CG2 3.36Å; A191-V195 PolarHBondContact O-N 3.48Å; G192-V195 PolarHBondContact O-N 3.22Å; I193-V195 VanDerWaalsContact C-N 3.29Å; I193-V195 PolarHBondContact O-N 2.95Å; V195-V197 VanDerWaalsContact C-N 3.3Å; V195-V197 PolarHBondContact O-N 3.34Å; V195-A198 WeakPolarHBondContact O-CB 3.37Å; V195-A198 PolarHBondContact O-N 3.24Å; V195-M204 HydrophobicContact CG1-CG 4.02Å; V195-F207 HydrophobicContact CG2-CB 3.59Å; V195-R208 HydrophobicContact CG2-CB 4.32Å; V195-Q267 HydrophobicContact CB-CG 4.17Å; V195-Q267 HydrophobicContact CG1-CG 3.94Å
196A95.8Very high96.2Very high4 Ų442.3 Ų42.33%0.03324%0.239CC..Hα-helixtrans-68.4-24.8-178.100000114.1G192 I193 L194 R264 Q267 V268G192-A196 PolarHBondContact O-N 3.37Å; I193-A196 WeakPolarHBondContact O-CB 3.48Å; I193-A196 PolarHBondContact O-N 2.84Å; L194-A196 VanDerWaalsContact C-N 3.34Å; A196-R264 WeakPolarHBondContact O-CD 3.14Å; A196-R264 WeakPolarHBondContact O-CG 3.48Å; A196-R264 PolarHBondContact O-NH1 3.46Å; A196-Q267 HydrophobicContact CB-CB 4.03Å; A196-Q267 HydrophobicContact CB-CG 3.8Å; A196-V268 HydrophobicContact CB-CG2 3.6Å
197V96.4Very high96.2Very high101 Ų10140.4 Ų40.461%0.61223%0.228SC*.THydrogen-bonded Turntrans-1054.5-179-172.20000111.7I193 L194 V195I193-V197 HydrophobicContact CG2-CG2 4.3Å; I193-V197 WeakPolarHBondContact O-CG2 3.38Å; I193-V197 PolarHBondContact O-N 3.26Å; L194-V197 PolarHBondContact O-N 3.42Å; V195-V197 VanDerWaalsContact C-N 3.3Å; V195-V197 PolarHBondContact O-N 3.34Å
198A96.1Very high96.2Very high0 Ų037.8 Ų37.80%021%0.214CC..  trans-57.2129.9-177.600000111.4L194 V195 M204 F207 R264L194-A198 PolarHBondContact O-N 2.94Å; V195-A198 WeakPolarHBondContact O-CB 3.37Å; V195-A198 PolarHBondContact O-N 3.24Å; A198-M204 HydrophobicContact CB-CB 3.69Å; A198-M204 HydrophobicContact CB-CG 4.19Å; A198-F207 HydrophobicContact CB-CD2 4.21Å; A198-F207 HydrophobicContact CB-CE2 4.49Å; A198-R264 PolarHBondContact O-NH1 3.04Å; A198-R264 VanDerWaalsContact O-NH1 3.12Å; A198-R264 PolarHBondContact O-NH2 3.47Å
199P93.4Very high96.3Very high102 Ų10239.6 Ų39.666%0.66223%0.225SC*.SBendtrans-86.4-21.8-177.432.5-35.5000113.3
200N94.8Very high96.3Very high74 Ų7442.7 Ų42.740%0.39624%0.241SC..SBendtrans-139.5161.6179.165.945.9000110.2I202 S203 M204N200-I202 PolarHBondContact O-N 3.21Å; N200-I202 PolarHBondContact OD1-N 3.22Å; N200-S203 PolarHBondContact O-N 2.73Å; N200-S203 WeakPolarHBondContact OD1-CB 3.34Å; N200-S203 PolarHBondContact OD1-N 3.16Å; N200-S203 PolarHBondContact OD1-OG 3.12Å; N200-M204 PolarHBondContact O-N 3.05Å; N200-M204 VanDerWaalsContact O-N 3.09Å
201Y94Very high96.3Very high17 Ų1739.6 Ų39.67%0.06722%0.222CC..Hα-helixtrans-64.7-38.6-174.7-170-105.4000113.3F136 F140 L142 V149 M204 L205F136-Y201 AromaticContact CD2-CE2 3.92Å; F136-Y201 HydrophobicContact CD2-CE2 3.92Å; F136-Y201 AromaticContact CE2-CE2 3.97Å; F136-Y201 HydrophobicContact CE2-CE2 3.97Å; F140-Y201 HydrophobicContact CB-CD2 4.46Å; F140-Y201 AromaticContact CD2-CD2 3.82Å; F140-Y201 HydrophobicContact CD2-CD2 3.82Å; F140-Y201 HydrophobicContact CE2-CD2 4.38Å; F140-Y201 HydrophobicContact CG-CD2 4.27Å; L142-Y201 HydrophobicContact CD1-CD2 3.45Å; L142-Y201 VanDerWaalsContact CD1-CD2 3.45Å; L142-Y201 HydrophobicContact CD1-CE1 4.39Å; L142-Y201 HydrophobicContact CD1-CE2 3.25Å; L142-Y201 HydrophobicContact CD1-CG 4.1Å; L142-Y201 HydrophobicContact CD2-CG 4.45Å; V149-Y201 HydrophobicContact CB-CE1 4.4Å; V149-Y201 HydrophobicContact CG1-CD1 3.55Å; V149-Y201 HydrophobicContact CG1-CE1 3.09Å; V149-Y201 PolarHBondContact O-OH 3.02Å; Y201-M204 HydrophobicContact CD2-CE 3.28Å; Y201-M204 HydrophobicContact CE2-CE 3.17Å; Y201-M204 HydrophobicContact CG-CE 4.47Å; Y201-M204 WeakPolarHBondContact O-CA 3.21Å; Y201-M204 VanDerWaalsContact O-CB 3.3Å; Y201-M204 WeakPolarHBondContact O-CB 3.36Å; Y201-M204 PolarHBondContact O-N 3.1Å; Y201-M204 VanDerWaalsContact O-N 3.16Å; Y201-L205 HydrophobicContact CD1-CD1 4.02Å; Y201-L205 HydrophobicContact CD1-CG 4.04Å; Y201-L205 HydrophobicContact CE1-CD1 3.57Å; Y201-L205 HydrophobicContact CE1-CD2 3.76Å; Y201-L205 HydrophobicContact CE1-CG 3.63Å; Y201-L205 HydrophobicContact CE2-CD2 4.49Å; Y201-L205 WeakPolarHBondContact O-CG 3.35Å; Y201-L205 PolarHBondContact O-N 2.8Å
202I95.3Very high96.2Very high116 Ų11639.5 Ų39.560%0.59522%0.221SC*.Hα-helixtrans-65.3-45.1-179.4-58.5-58.2000111.4N200 M204 L205 V206N200-I202 PolarHBondContact O-N 3.21Å; N200-I202 PolarHBondContact OD1-N 3.22Å; I202-M204 VanDerWaalsContact C-N 3.26Å; I202-M204 PolarHBondContact O-N 2.97Å; I202-L205 PolarHBondContact O-N 3.2Å; I202-V206 WeakPolarHBondContact O-CG2 3.46Å; I202-V206 PolarHBondContact O-N 3.02Å
203S96.2Very high96.1Very high36 Ų3641.7 Ų41.725%0.25223%0.231SC..Hα-helixtrans-60.1-39.3173.2-65.60000111N200 L205 V206 F207N200-S203 PolarHBondContact O-N 2.73Å; N200-S203 WeakPolarHBondContact OD1-CB 3.34Å; N200-S203 PolarHBondContact OD1-N 3.16Å; N200-S203 PolarHBondContact OD1-OG 3.12Å; S203-L205 PolarHBondContact O-N 2.76Å; S203-V206 PolarHBondContact O-N 2.62Å; S203-F207 WeakPolarHBondContact O-CD2 2.98Å; S203-F207 VanDerWaalsContact O-CG 3.25Å; S203-F207 WeakPolarHBondContact O-CG 3.28Å; S203-F207 PolarHBondContact O-N 3.25Å
204M95.8Very high96Very high0 Ų038.6 Ų38.60%022%0.215CC..Hα-helixtrans-59.8-45.8174.8-169.9174.171.300111.8F136 F140 Y153 V195 A198 N200 Y201 I202 V206 F207 R208 W263F136-M204 HydrophobicContact CB-CE 3.98Å; F136-M204 HydrophobicContact CB-SD 4.25Å; F136-M204 HydrophobicContact CD1-CE 4.5Å; F136-M204 HydrophobicContact CD2-CE 3.72Å; F136-M204 HydrophobicContact CE2-CE 4.35Å; F136-M204 HydrophobicContact CG-CE 3.82Å; F140-M204 HydrophobicContact CD2-CE 4.24Å; F140-M204 HydrophobicContact CE2-CE 4Å; F140-M204 HydrophobicContact CE2-SD 3.92Å; Y153-M204 HydrophobicContact CD2-CE 3.74Å; Y153-M204 HydrophobicContact CE2-CE 3.78Å; Y153-M204 HydrophobicContact CE2-CG 4.05Å; Y153-M204 HydrophobicContact CE2-SD 3.99Å; V195-M204 HydrophobicContact CG1-CG 4.02Å; A198-M204 HydrophobicContact CB-CB 3.69Å; A198-M204 HydrophobicContact CB-CG 4.19Å; N200-M204 PolarHBondContact O-N 3.05Å; N200-M204 VanDerWaalsContact O-N 3.09Å; Y201-M204 HydrophobicContact CD2-CE 3.28Å; Y201-M204 HydrophobicContact CE2-CE 3.17Å; Y201-M204 HydrophobicContact CG-CE 4.47Å; Y201-M204 WeakPolarHBondContact O-CA 3.21Å; Y201-M204 VanDerWaalsContact O-CB 3.3Å; Y201-M204 WeakPolarHBondContact O-CB 3.36Å; Y201-M204 PolarHBondContact O-N 3.1Å; Y201-M204 VanDerWaalsContact O-N 3.16Å; I202-M204 VanDerWaalsContact C-N 3.26Å; I202-M204 PolarHBondContact O-N 2.97Å; M204-V206 PolarHBondContact O-N 3.32Å; M204-F207 PolarHBondContact O-N 3.43Å; M204-R208 WeakPolarHBondContact O-CB 3.42Å; M204-R208 PolarHBondContact O-N 3.48Å; M204-W263 HydrophobicContact SD-CH2 3.61Å; M204-W263 HydrophobicContact SD-CZ3 3.81Å
205L96.8Very high95.8Very high17 Ų1735.5 Ų35.59%0.08920%0.199CC..Hα-helixtrans-61.8-41.2176-68.3-173.9000112.9M152 Y153 T156 Y201 I202 S203 R208 T209M152-L205 HydrophobicContact CB-CD1 4.08Å; M152-L205 HydrophobicContact CB-CD2 4.23Å; M152-L205 HydrophobicContact SD-CD1 4.43Å; Y153-L205 HydrophobicContact CD2-CD2 4.41Å; T156-L205 HydrophobicContact CG2-CB 4.38Å; T156-L205 HydrophobicContact CG2-CD2 4.34Å; Y201-L205 HydrophobicContact CD1-CD1 4.02Å; Y201-L205 HydrophobicContact CD1-CG 4.04Å; Y201-L205 HydrophobicContact CE1-CD1 3.57Å; Y201-L205 HydrophobicContact CE1-CD2 3.76Å; Y201-L205 HydrophobicContact CE1-CG 3.63Å; Y201-L205 HydrophobicContact CE2-CD2 4.49Å; Y201-L205 WeakPolarHBondContact O-CG 3.35Å; Y201-L205 PolarHBondContact O-N 2.8Å; I202-L205 PolarHBondContact O-N 3.2Å; S203-L205 PolarHBondContact O-N 2.76Å; L205-R208 PolarHBondContact O-N 3.47Å; L205-T209 PolarHBondContact O-N 2.95Å; L205-T209 PolarHBondContact O-OG1 3.26Å
206V97.6Very high95.4Very high76 Ų7636.8 Ų36.846%0.46121%0.205SC..Hα-helixtrans-62.6-49.9177172.40000110.3I202 S203 M204 R208 T209 I210I202-V206 WeakPolarHBondContact O-CG2 3.46Å; I202-V206 PolarHBondContact O-N 3.02Å; S203-V206 PolarHBondContact O-N 2.62Å; M204-V206 PolarHBondContact O-N 3.32Å; V206-R208 VanDerWaalsContact C-N 3.28Å; V206-R208 PolarHBondContact O-N 2.97Å; V206-T209 WeakPolarHBondContact O-CB 3.22Å; V206-T209 PolarHBondContact O-N 3.48Å; V206-I210 HydrophobicContact CG1-CD1 4.23Å; V206-I210 WeakPolarHBondContact O-CG1 3.48Å; V206-I210 PolarHBondContact O-N 3.32Å; V206-I210 VanDerWaalsContact O-N 3.08Å
207F97.4Very high95Very high48 Ų4836.6 Ų36.621%0.21120%0.203CC..Hα-helixtrans-64.1-35177.5-59.5-38.5000112L194 V195 A198 S203 M204 T209 I210 F211L194-F207 HydrophobicContact CB-CB 4.12Å; L194-F207 HydrophobicContact CB-CD1 3.91Å; L194-F207 HydrophobicContact CB-CD2 3.73Å; L194-F207 HydrophobicContact CB-CE1 4.23Å; L194-F207 HydrophobicContact CB-CE2 4.05Å; L194-F207 HydrophobicContact CB-CG 3.66Å; L194-F207 HydrophobicContact CB-CZ 4.3Å; L194-F207 HydrophobicContact CD1-CD1 4.03Å; L194-F207 HydrophobicContact CD1-CE1 3.99Å; L194-F207 HydrophobicContact CD2-CZ 4.41Å; L194-F207 VanDerWaalsContact O-CD2 3.26Å; L194-F207 WeakPolarHBondContact O-CD2 3.38Å; V195-F207 HydrophobicContact CG2-CB 3.59Å; A198-F207 HydrophobicContact CB-CD2 4.21Å; A198-F207 HydrophobicContact CB-CE2 4.49Å; S203-F207 WeakPolarHBondContact O-CD2 2.98Å; S203-F207 VanDerWaalsContact O-CG 3.25Å; S203-F207 WeakPolarHBondContact O-CG 3.28Å; S203-F207 PolarHBondContact O-N 3.25Å; M204-F207 PolarHBondContact O-N 3.43Å; F207-T209 VanDerWaalsContact C-N 3.34Å; F207-T209 PolarHBondContact O-N 3.09Å; F207-I210 HydrophobicContact CD1-CD1 4.45Å; F207-I210 PolarHBondContact O-N 3.01Å; F207-F211 WeakPolarHBondContact O-CB 3.31Å; F207-F211 PolarHBondContact O-N 2.97Å
208R95.8Very high94.6Very high0 Ų031.9 Ų31.90%018%0.175CC..Hα-helixtrans-64.1-38.4175.1-171.262.3167.3143.3-1.2112.1V35 Y153 L157 V195 M204 L205 V206 F211 G212V35-R208 VanDerWaalsContact CG1-NH1 3.29Å; V35-R208 PolarHBondContact O-NH1 3.44Å; V35-R208 VanDerWaalsContact O-NH1 3.11Å; V35-R208 PolarHBondContact O-NH2 3.48Å; Y153-R208 HydrophobicContact CD2-CG 4.24Å; Y153-R208 HydrophobicContact CE2-CB 4.45Å; Y153-R208 HydrophobicContact CE2-CG 4.04Å; Y153-R208 VanDerWaalsContact CZ-NE 3.27Å; Y153-R208 WeakPolarHBondContact O-CG 3.28Å; Y153-R208 PolarHBondContact OH-NE 3.11Å; L157-R208 HydrophobicContact CB-CG 4.28Å; L157-R208 HydrophobicContact CD1-CG 4.4Å; L157-R208 VanDerWaalsContact CD1-NH1 3.33Å; V195-R208 HydrophobicContact CG2-CB 4.32Å; M204-R208 WeakPolarHBondContact O-CB 3.42Å; M204-R208 PolarHBondContact O-N 3.48Å; L205-R208 PolarHBondContact O-N 3.47Å; V206-R208 VanDerWaalsContact C-N 3.28Å; V206-R208 PolarHBondContact O-N 2.97Å; R208-F211 PolarHBondContact O-N 3.42Å; R208-G212 PolarHBondContact O-N 2.98Å
209T97.4Very high94.3Very high41 Ų4135.2 Ų35.225%0.25219%0.187SC..Hα-helixtrans-63.7-46.8173.9-51.90000111.2T156 V159 G160 L205 V206 F207 F211 G212 F213T156-T209 WeakPolarHBondContact CB-OG1 3.43Å; V159-T209 HydrophobicContact CG1-CG2 4.49Å; G160-T209 WeakPolarHBondContact CA-O 3.31Å; L205-T209 PolarHBondContact O-N 2.95Å; L205-T209 PolarHBondContact O-OG1 3.26Å; V206-T209 WeakPolarHBondContact O-CB 3.22Å; V206-T209 PolarHBondContact O-N 3.48Å; F207-T209 VanDerWaalsContact C-N 3.34Å; F207-T209 PolarHBondContact O-N 3.09Å; T209-F211 VanDerWaalsContact C-N 3.27Å; T209-F211 PolarHBondContact O-N 3.23Å; T209-G212 PolarHBondContact O-N 3.24Å; T209-F213 WeakPolarHBondContact O-CB 3.3Å; T209-F213 PolarHBondContact O-N 2.96Å
210I97.4Very high93.9Very high64 Ų6432.3 Ų32.333%0.32817%0.166SC..Hα-helixtrans-62.7-38.7176.8-62.3168.7000110.4L187 A191 V206 F207 F213 A214L187-I210 HydrophobicContact CD1-CG2 3.82Å; L187-I210 HydrophobicContact CD2-CG2 4.33Å; L187-I210 HydrophobicContact CG-CG2 4.08Å; A191-I210 HydrophobicContact CB-CB 4.25Å; A191-I210 HydrophobicContact CB-CG2 3.83Å; V206-I210 HydrophobicContact CG1-CD1 4.23Å; V206-I210 WeakPolarHBondContact O-CG1 3.48Å; V206-I210 PolarHBondContact O-N 3.32Å; V206-I210 VanDerWaalsContact O-N 3.08Å; F207-I210 HydrophobicContact CD1-CD1 4.45Å; F207-I210 PolarHBondContact O-N 3.01Å; I210-F213 WeakPolarHBondContact O-CB 3.45Å; I210-F213 PolarHBondContact O-N 3.16Å; I210-A214 PolarHBondContact O-N 2.79Å
211F95.9Very high93.6Very high0 Ų028.9 Ų28.90%015%0.147CC..Hα-helixtrans-64.5-43.2177-169.1-154.3000111.4V35 N188 A191 F207 R208 T209 A214 V215 Y274V35-F211 HydrophobicContact CB-CE1 4.13Å; V35-F211 HydrophobicContact CB-CZ 4.23Å; V35-F211 HydrophobicContact CG1-CD1 3.9Å; V35-F211 HydrophobicContact CG1-CE1 3.62Å; V35-F211 HydrophobicContact CG1-CG 4.45Å; V35-F211 HydrophobicContact CG1-CZ 4Å; V35-F211 HydrophobicContact CG2-CE1 3.5Å; V35-F211 HydrophobicContact CG2-CE2 4Å; V35-F211 HydrophobicContact CG2-CZ 3.2Å; N188-F211 HydrophobicContact CB-CD2 4.31Å; N188-F211 HydrophobicContact CB-CE2 3.99Å; N188-F211 WeakPolarHBondContact O-CD2 3.24Å; N188-F211 VanDerWaalsContact O-CE2 3.27Å; N188-F211 WeakPolarHBondContact O-CE2 3.47Å; N188-F211 PolarHBondContact OD1-O 3.18Å; A191-F211 HydrophobicContact CB-CB 3.9Å; A191-F211 HydrophobicContact CB-CD2 4.4Å; A191-F211 HydrophobicContact CB-CG 4.48Å; F207-F211 WeakPolarHBondContact O-CB 3.31Å; F207-F211 PolarHBondContact O-N 2.97Å; R208-F211 PolarHBondContact O-N 3.42Å; T209-F211 VanDerWaalsContact C-N 3.27Å; T209-F211 PolarHBondContact O-N 3.23Å; F211-A214 PolarHBondContact O-N 3.02Å; F211-V215 HydrophobicContact CD2-CG2 3.93Å; F211-V215 HydrophobicContact CE2-CG2 3.77Å; F211-V215 HydrophobicContact CZ-CG2 4.42Å; F211-V215 WeakPolarHBondContact O-CB 3.39Å; F211-V215 WeakPolarHBondContact O-CG2 3.45Å; F211-V215 PolarHBondContact O-N 2.93Å; F211-Y274 HydrophobicContact CE2-CD2 4.47Å; F211-Y274 HydrophobicContact CE2-CE2 4.09Å; F211-Y274 HydrophobicContact CZ-CE2 4.15Å
212G95.3Very high93.4Very high0 Ų028.1 Ų28.10%015%0.145CC..Hα-helixtrans-58.3-51.4172.300000112.3F161 R208 T209 A214 V215 K216F161-G212 WeakPolarHBondContact CD1-O 3.36Å; F161-G212 WeakPolarHBondContact CE1-O 3.37Å; R208-G212 PolarHBondContact O-N 2.98Å; T209-G212 PolarHBondContact O-N 3.24Å; G212-A214 VanDerWaalsContact C-N 3.26Å; G212-A214 PolarHBondContact O-N 3.01Å; G212-V215 PolarHBondContact O-N 3.14Å; G212-V215 VanDerWaalsContact O-N 3.11Å; G212-K216 PolarHBondContact O-N 3.34Å
213F95Very high93Very high45 Ų4525.7 Ų25.720%0.19713%0.128CC..Hα-helixtrans-49.5-47177.5169.5-92.8000112.8G160 V163 G164 T167 F168 L187 T209 I210 G217G160-F213 WeakPolarHBondContact O-CA 3.42Å; G160-F213 PolarHBondContact O-N 3.4Å; V163-F213 HydrophobicContact CB-CD2 4.26Å; V163-F213 HydrophobicContact CG1-CD2 3.96Å; V163-F213 HydrophobicContact CG1-CE2 4.08Å; G164-F213 WeakPolarHBondContact CA-O 3.4Å; T167-F213 HydrophobicContact CG2-CE2 3.93Å; T167-F213 HydrophobicContact CG2-CZ 3.79Å; F168-F213 HydrophobicContact CD2-CE1 4.14Å; F168-F213 HydrophobicContact CD2-CE2 4.44Å; F168-F213 HydrophobicContact CD2-CZ 4.03Å; F168-F213 AromaticContact CE2-CD1 3.78Å; F168-F213 HydrophobicContact CE2-CD1 3.78Å; F168-F213 AromaticContact CE2-CE1 3.32Å; F168-F213 HydrophobicContact CE2-CE1 3.32Å; F168-F213 HydrophobicContact CE2-CE2 4.38Å; F168-F213 HydrophobicContact CE2-CG 4.47Å; F168-F213 AromaticContact CE2-CZ 3.66Å; F168-F213 HydrophobicContact CE2-CZ 3.66Å; F168-F213 HydrophobicContact CZ-CE1 4.05Å; L187-F213 HydrophobicContact CD2-CD1 3.75Å; L187-F213 HydrophobicContact CD2-CE1 3.81Å; T209-F213 WeakPolarHBondContact O-CB 3.3Å; T209-F213 PolarHBondContact O-N 2.96Å; I210-F213 WeakPolarHBondContact O-CB 3.45Å; I210-F213 PolarHBondContact O-N 3.16Å; F213-G217 PolarHBondContact O-N 2.74Å
214A95.3Very high92.5Very high0 Ų026.4 Ų26.40%013%0.131CC..Hα-helixtrans-73.1-38.1179.800000113.1S184 L187 N188 I210 F211 G212 G217 G218S184-A214 WeakPolarHBondContact CB-O 3.48Å; L187-A214 HydrophobicContact CB-CB 3.75Å; L187-A214 HydrophobicContact CD2-CB 3.82Å; L187-A214 HydrophobicContact CG-CB 3.67Å; N188-A214 HydrophobicContact CB-CB 4.44Å; N188-A214 PolarHBondContact ND2-O 3.37Å; N188-A214 WeakPolarHBondContact OD1-CB 3.3Å; I210-A214 PolarHBondContact O-N 2.79Å; F211-A214 PolarHBondContact O-N 3.02Å; G212-A214 VanDerWaalsContact C-N 3.26Å; G212-A214 PolarHBondContact O-N 3.01Å; A214-G217 PolarHBondContact O-N 2.91Å; A214-G218 PolarHBondContact O-N 3.32Å
215V93.1Very high92.2Very high4 Ų426.4 Ų26.42%0.02413%0.131CC..Hα-helixtrans-67-47.6-177158.20000111.3F32 V35 F161 N188 F211 G212 G217 G218 W219F32-V215 HydrophobicContact CD2-CG1 3.11Å; F32-V215 HydrophobicContact CE2-CG1 3.27Å; F32-V215 HydrophobicContact CG-CG1 4.25Å; V35-V215 HydrophobicContact CB-CG2 4.32Å; V35-V215 HydrophobicContact CG1-CB 4.45Å; V35-V215 HydrophobicContact CG1-CG1 4.38Å; V35-V215 HydrophobicContact CG1-CG2 3.89Å; V35-V215 HydrophobicContact CG2-CG2 4.08Å; F161-V215 HydrophobicContact CE1-CB 4.13Å; F161-V215 HydrophobicContact CE1-CG1 3.88Å; F161-V215 HydrophobicContact CZ-CG1 4.23Å; N188-V215 WeakPolarHBondContact ND2-CA 3.21Å; N188-V215 VanDerWaalsContact OD1-CA 3.31Å; N188-V215 WeakPolarHBondContact OD1-CA 3.39Å; N188-V215 WeakPolarHBondContact OD1-CG2 3.1Å; N188-V215 PolarHBondContact OD1-N 3.02Å; F211-V215 HydrophobicContact CD2-CG2 3.93Å; F211-V215 HydrophobicContact CE2-CG2 3.77Å; F211-V215 HydrophobicContact CZ-CG2 4.42Å; F211-V215 WeakPolarHBondContact O-CB 3.39Å; F211-V215 WeakPolarHBondContact O-CG2 3.45Å; F211-V215 PolarHBondContact O-N 2.93Å; G212-V215 PolarHBondContact O-N 3.14Å; G212-V215 VanDerWaalsContact O-N 3.11Å; V215-G217 VanDerWaalsContact C-N 3.3Å; V215-G217 PolarHBondContact O-N 3.34Å; V215-G218 PolarHBondContact O-N 3.12Å; V215-W219 PolarHBondContact O-N 2.86Å
216K89.7Confident91.9Very high28 Ų2825.8 Ų25.812%0.12213%0.128CC..Hα-helixtrans-60.4-43.5178.5-174.277.8172.3-1480110.9F161 G212 G218 W219 M220 D474F161-K216 HydrophobicContact CB-CB 4.06Å; F161-K216 HydrophobicContact CB-CD 4.08Å; F161-K216 HydrophobicContact CB-CG 4.16Å; F161-K216 HydrophobicContact CD1-CB 3.73Å; F161-K216 HydrophobicContact CE1-CB 4.43Å; F161-K216 HydrophobicContact CG-CB 4.07Å; F161-K216 HydrophobicContact CG-CD 4.22Å; F161-K216 HydrophobicContact CG-CG 4.5Å; F161-K216 WeakPolarHBondContact O-CG 3.14Å; G212-K216 PolarHBondContact O-N 3.34Å; K216-G218 VanDerWaalsContact C-N 3.35Å; K216-G218 PolarHBondContact O-N 3.09Å; K216-W219 PolarHBondContact O-N 2.85Å; K216-M220 WeakPolarHBondContact O-CG 3.33Å; K216-M220 PolarHBondContact O-N 2.93Å; K216-D474 IonicContact NZ-OD1 3.17Å; K216-D474 PolarHBondContact NZ-OD1 3.41Å; K216-D474 IonicContact NZ-OD2 3.47Å
217G86.5Confident91.2Very high0 Ų023.2 Ų23.20%011%0.112CC..Hα-helixtrans-61.4-41.2178.700000113.7F168 F213 A214 V215 S221F168-G217 VanDerWaalsContact CG-CA 3.41Å; F213-G217 PolarHBondContact O-N 2.74Å; A214-G217 PolarHBondContact O-N 2.91Å; V215-G217 VanDerWaalsContact C-N 3.3Å; V215-G217 PolarHBondContact O-N 3.34Å; G217-S221 WeakPolarHBondContact O-CB 3.48Å; G217-S221 PolarHBondContact O-N 3.47Å; G217-S221 PolarHBondContact O-OG 3.41Å
218G88.8Confident90.7Very high2 Ų222.3 Ų22.32%0.02111%0.109CC..Hα-helixtrans-64.4-49.9175.100000112.3S184 A214 V215 K216 M220 S221 V222S184-G218 WeakPolarHBondContact OG-CA 3.44Å; S184-G218 PolarHBondContact OG-N 3Å; A214-G218 PolarHBondContact O-N 3.32Å; V215-G218 PolarHBondContact O-N 3.12Å; K216-G218 VanDerWaalsContact C-N 3.35Å; K216-G218 PolarHBondContact O-N 3.09Å; G218-M220 VanDerWaalsContact C-N 3.34Å; G218-M220 PolarHBondContact O-N 3.48Å; G218-S221 PolarHBondContact O-N 2.99Å; G218-V222 WeakPolarHBondContact O-CG2 3.36Å; G218-V222 PolarHBondContact O-N 3.09Å
219W88.2Confident90.2Very high69 Ų6922.5 Ų22.526%0.26111%0.11SC..Hα-helixtrans-58.4-44.7179.4-17487.7000112.2F32 V215 K216 V222 Y223F32-W219 AromaticContact CD1-CD1 3.72Å; F32-W219 HydrophobicContact CD1-CG 4.43Å; F32-W219 AromaticContact CE1-CD1 3.91Å; F32-W219 HydrophobicContact CE1-CG 4.31Å; V215-W219 PolarHBondContact O-N 2.86Å; K216-W219 PolarHBondContact O-N 2.85Å; W219-V222 PolarHBondContact O-N 3.31Å; W219-Y223 PolarHBondContact O-N 3.36Å
220M85.3Confident89.7Confident42 Ų4220.7 Ų20.721%0.20710%0.098CC..Hα-helixtrans-66.1-42.1176.7-67.6-161.4-3700112.8S165 K216 G218 V222 Y223 V224S165-M220 VanDerWaalsContact CA-CE 3.41Å; S165-M220 WeakPolarHBondContact O-CE 3.35Å; K216-M220 WeakPolarHBondContact O-CG 3.33Å; K216-M220 PolarHBondContact O-N 2.93Å; G218-M220 VanDerWaalsContact C-N 3.34Å; G218-M220 PolarHBondContact O-N 3.48Å; M220-V222 VanDerWaalsContact C-N 3.26Å; M220-V222 PolarHBondContact O-N 3.31Å; M220-Y223 PolarHBondContact O-N 3.01Å; M220-V224 WeakPolarHBondContact O-CG2 3.44Å; M220-V224 PolarHBondContact O-N 3.46Å
221S88.8Confident88.8Confident1 Ų117.7 Ų17.71%0.0078%0.083CC..Hα-helixtrans-61.3-38.2177.5-60.30000111.4S180 G217 G218 L225S180-S221 PolarHBondContact OG-OG 2.97Å; S180-S221 VanDerWaalsContact OG-OG 3.12Å; G217-S221 WeakPolarHBondContact O-CB 3.48Å; G217-S221 PolarHBondContact O-N 3.47Å; G217-S221 PolarHBondContact O-OG 3.41Å; G218-S221 PolarHBondContact O-N 2.99Å; S221-L225 VanDerWaalsContact O-CB 3.22Å; S221-L225 WeakPolarHBondContact O-CB 3.4Å; S221-L225 PolarHBondContact O-N 3.25Å
222V90.5Very high87.8Confident2 Ų220.9 Ų20.91%0.01210%0.103CC..Hα-helixtrans-63.5-51.6173.3170.70000111.3L25 V28 F181 G218 W219 M220 V224 L225 I226 L242L25-V222 HydrophobicContact CB-CG1 3.86Å; L25-V222 HydrophobicContact CD2-CG1 4.31Å; L25-V222 HydrophobicContact CD2-CG2 4.15Å; L25-V222 HydrophobicContact CG-CG1 4.48Å; V28-V222 HydrophobicContact CG1-CG2 4.44Å; F181-V222 HydrophobicContact CD2-CG2 3.31Å; F181-V222 HydrophobicContact CE2-CG2 3.21Å; F181-V222 HydrophobicContact CG-CG2 4.42Å; F181-V222 HydrophobicContact CZ-CG2 4.29Å; G218-V222 WeakPolarHBondContact O-CG2 3.36Å; G218-V222 PolarHBondContact O-N 3.09Å; W219-V222 PolarHBondContact O-N 3.31Å; M220-V222 VanDerWaalsContact C-N 3.26Å; M220-V222 PolarHBondContact O-N 3.31Å; V222-V224 VanDerWaalsContact C-N 3.34Å; V222-V224 PolarHBondContact O-N 3.39Å; V222-L225 PolarHBondContact O-N 3.15Å; V222-I226 HydrophobicContact CG1-CD1 3.53Å; V222-I226 HydrophobicContact CG1-CG1 4.23Å; V222-I226 WeakPolarHBondContact O-CB 3.43Å; V222-I226 VanDerWaalsContact O-CG1 3.27Å; V222-I226 WeakPolarHBondContact O-CG1 3.32Å; V222-I226 PolarHBondContact O-N 2.9Å; V222-L242 HydrophobicContact CG1-CD1 4.35Å
223Y87.5Confident87Confident65 Ų6526.6 Ų26.626%0.25513%0.129SC..Hα-helixtrans-58.6-45.8-177.8-179.2-98000112W219 M220 T227 L242W219-Y223 PolarHBondContact O-N 3.36Å; M220-Y223 PolarHBondContact O-N 3.01Å; Y223-T227 HydrophobicContact CE1-CG2 4.2Å; Y223-T227 HydrophobicContact CE2-CG2 4.3Å; Y223-T227 WeakPolarHBondContact O-CG2 3.22Å; Y223-T227 PolarHBondContact O-N 3.21Å; Y223-T227 PolarHBondContact O-OG1 3.03Å; Y223-L242 HydrophobicContact CD2-CD2 3.93Å
224V85.8Confident86.4Confident50 Ų5028.7 Ų28.730%0.30314%0.137SC..Hα-helixtrans-64.1-49.1176.81760000110.7R177 M220 V222 I226 T227 E228R177-V224 HydrophobicContact CG-CG1 4.12Å; M220-V224 WeakPolarHBondContact O-CG2 3.44Å; M220-V224 PolarHBondContact O-N 3.46Å; V222-V224 VanDerWaalsContact C-N 3.34Å; V222-V224 PolarHBondContact O-N 3.39Å; V224-I226 VanDerWaalsContact C-N 3.3Å; V224-I226 PolarHBondContact O-N 3.38Å; V224-T227 WeakPolarHBondContact CA-OG1 3.1Å; V224-T227 PolarHBondContact O-N 3.4Å; V224-T227 PolarHBondContact O-OG1 2.89Å; V224-E228 HydrophobicContact CG1-CG 4.17Å; V224-E228 VanDerWaalsContact O-CG 3.3Å; V224-E228 WeakPolarHBondContact O-CG 3.44Å; V224-E228 PolarHBondContact O-N 3.39Å
225L89.4Confident85.8Confident1 Ų131.5 Ų31.51%0.00515%0.147CC..Hα-helixtrans-57.3-44.6-179.5-179.960.1000112.1L25 R177 S221 V222 E228 L229 I284L25-L225 HydrophobicContact CD1-CD2 4.03Å; L25-L225 HydrophobicContact CD1-CG 4.35Å; R177-L225 HydrophobicContact CB-CB 4.19Å; R177-L225 HydrophobicContact CB-CD1 4.24Å; S221-L225 VanDerWaalsContact O-CB 3.22Å; S221-L225 WeakPolarHBondContact O-CB 3.4Å; S221-L225 PolarHBondContact O-N 3.25Å; V222-L225 PolarHBondContact O-N 3.15Å; L225-E228 PolarHBondContact O-N 3.08Å; L225-L229 HydrophobicContact CD1-CD1 3.99Å; L225-L229 HydrophobicContact CD1-CG 4.33Å; L225-L229 HydrophobicContact CG-CD1 4.03Å; L225-L229 WeakPolarHBondContact O-CB 3.39Å; L225-L229 VanDerWaalsContact O-CG 3.23Å; L225-L229 WeakPolarHBondContact O-CG 3.47Å; L225-L229 PolarHBondContact O-N 3.18Å; L225-I284 HydrophobicContact CD2-CG2 3.8Å
226I89.1Confident85.1Confident4 Ų435.6 Ų35.62%0.02116%0.162CC..Hα-helixtrans-62.4-48.2178.3-71.6172.5000111F22 L25 V222 V224 E228 L229 V230 V238 L242F22-I226 HydrophobicContact CD2-CD1 4.07Å; F22-I226 HydrophobicContact CD2-CG1 4.49Å; F22-I226 HydrophobicContact CD2-CG2 3.82Å; F22-I226 HydrophobicContact CE2-CD1 4.33Å; F22-I226 HydrophobicContact CE2-CG2 4.29Å; L25-I226 HydrophobicContact CB-CD1 3.73Å; L25-I226 HydrophobicContact CB-CG1 4.03Å; L25-I226 HydrophobicContact CD1-CD1 4.12Å; L25-I226 HydrophobicContact CD1-CG1 3.44Å; L25-I226 VanDerWaalsContact CD1-CG1 3.44Å; L25-I226 HydrophobicContact CG-CG1 4.36Å; V222-I226 HydrophobicContact CG1-CD1 3.53Å; V222-I226 HydrophobicContact CG1-CG1 4.23Å; V222-I226 WeakPolarHBondContact O-CB 3.43Å; V222-I226 VanDerWaalsContact O-CG1 3.27Å; V222-I226 WeakPolarHBondContact O-CG1 3.32Å; V222-I226 PolarHBondContact O-N 2.9Å; V224-I226 VanDerWaalsContact C-N 3.3Å; V224-I226 PolarHBondContact O-N 3.38Å; I226-E228 VanDerWaalsContact C-N 3.28Å; I226-E228 PolarHBondContact O-N 2.95Å; I226-L229 PolarHBondContact O-N 2.94Å; I226-V230 WeakPolarHBondContact O-CG2 3.37Å; I226-V230 PolarHBondContact O-N 2.99Å; I226-V238 HydrophobicContact CB-CG1 4.41Å; I226-V238 HydrophobicContact CG2-CB 4.44Å; I226-V238 HydrophobicContact CG2-CG1 3Å; I226-L242 HydrophobicContact CD1-CD1 4.1Å
227T84.2Confident84.7Confident22 Ų2237.3 Ų37.314%0.13517%0.172CC..Hα-helixtrans-68.7-27.6-176.251.70000112.8Y223 V224 R235Y223-T227 HydrophobicContact CE1-CG2 4.2Å; Y223-T227 HydrophobicContact CE2-CG2 4.3Å; Y223-T227 WeakPolarHBondContact O-CG2 3.22Å; Y223-T227 PolarHBondContact O-N 3.21Å; Y223-T227 PolarHBondContact O-OG1 3.03Å; V224-T227 WeakPolarHBondContact CA-OG1 3.1Å; V224-T227 PolarHBondContact O-N 3.4Å; V224-T227 PolarHBondContact O-OG1 2.89Å; T227-R235 PolarHBondContact O-NE 3.23Å
228E85.6Confident84.7Confident28 Ų2837.4 Ų37.413%0.13117%0.172CC..Hα-helixtrans-76.1-27.1174.3-67.8-173.6150.100113.3R177 V224 L225 I226 S287 R289R177-E228 IonicContact CZ-OE1 2.64Å; R177-E228 IonicContact CZ-OE2 3.87Å; R177-E228 IonicContact NE-OE2 3.77Å; R177-E228 IonicContact NH1-OE1 2.64Å; R177-E228 PolarHBondContact NH1-OE1 3.47Å; R177-E228 IonicContact NH1-OE2 3.25Å; R177-E228 PolarHBondContact NH1-OE2 2.88Å; V224-E228 HydrophobicContact CG1-CG 4.17Å; V224-E228 VanDerWaalsContact O-CG 3.3Å; V224-E228 WeakPolarHBondContact O-CG 3.44Å; V224-E228 PolarHBondContact O-N 3.39Å; L225-E228 PolarHBondContact O-N 3.08Å; I226-E228 VanDerWaalsContact C-N 3.28Å; I226-E228 PolarHBondContact O-N 2.95Å; E228-S287 WeakPolarHBondContact OE2-CB 3.36Å; E228-S287 PolarHBondContact OE2-OG 3.46Å; E228-R289 HydrophobicContact CB-CG 4.35Å; E228-R289 PolarHBondContact O-NE 3.32Å; E228-R289 VanDerWaalsContact O-NE 3.14Å
229L85.6Confident84.4Confident4 Ų437.9 Ų37.92%0.02118%0.177CC..Hα-helixtrans-85.5-18.3178.7-73.1173.3000113.9Q18 I21 L225 I226 P288 I307Q18-L229 WeakPolarHBondContact CG-O 3.33Å; Q18-L229 PolarHBondContact NE2-O 3.43Å; I21-L229 HydrophobicContact CD1-CD1 4.49Å; I21-L229 HydrophobicContact CG2-CD1 3.89Å; L225-L229 HydrophobicContact CD1-CD1 3.99Å; L225-L229 HydrophobicContact CD1-CG 4.33Å; L225-L229 HydrophobicContact CG-CD1 4.03Å; L225-L229 WeakPolarHBondContact O-CB 3.39Å; L225-L229 VanDerWaalsContact O-CG 3.23Å; L225-L229 WeakPolarHBondContact O-CG 3.47Å; L225-L229 PolarHBondContact O-N 3.18Å; I226-L229 PolarHBondContact O-N 2.94Å; L229-P288 HydrophobicContact CD2-CG 4.2Å; L229-I307 HydrophobicContact CD2-CD1 4.33Å
230V86.3Confident84.2Confident3 Ų334.8 Ų34.82%0.01817%0.166CC..SBendtrans-108.3144.5-174.71770000111.1L8 F14 I226 Y234 V238L8-V230 VanDerWaalsContact CD2-C 3.49Å; L8-V230 WeakPolarHBondContact CD2-O 3.31Å; F14-V230 HydrophobicContact CD2-CG1 3.88Å; F14-V230 HydrophobicContact CD2-CG2 3.92Å; F14-V230 HydrophobicContact CE2-CG1 4.48Å; F14-V230 HydrophobicContact CE2-CG2 4.02Å; I226-V230 WeakPolarHBondContact O-CG2 3.37Å; I226-V230 PolarHBondContact O-N 2.99Å; V230-Y234 VanDerWaalsContact CG1-CB 3.45Å; V230-V238 HydrophobicContact CG1-CG2 4.24Å; V230-V238 HydrophobicContact CG2-CG2 4.44Å
231G78.8Confident84.3Confident1 Ų135 Ų351%0.0117%0.168CC..  trans-60.1152.7176.500000112.8N13 E233 Y234 R235N13-G231 PolarHBondContact O-N 3.04Å; G231-E233 PolarHBondContact O-N 3.37Å; G231-E233 VanDerWaalsContact O-N 3.13Å; G231-Y234 PolarHBondContact O-N 3.32Å; G231-Y234 VanDerWaalsContact O-N 3.07Å; G231-R235 PolarHBondContact O-N 2.97Å
232V76.4Confident84.2Confident67 Ų6735.2 Ų35.241%0.40617%0.168SC..G310 helixtrans-52.7-40-172.9-174.50000112.4D5 Y234 R235D5-V232 HydrophobicContact CB-CG2 4.11Å; D5-V232 VanDerWaalsContact OD1-CG2 3.29Å; D5-V232 WeakPolarHBondContact OD1-CG2 3.45Å; V232-Y234 VanDerWaalsContact C-N 3.32Å; V232-Y234 PolarHBondContact O-N 3.04Å; V232-R235 PolarHBondContact O-N 3.4Å
233E77.2Confident84Confident120 Ų12036.6 Ų36.656%0.56118%0.175SC*.G310 helixtrans-60.7-37-178.5-60.7-179.7145.800113.6N13 G231N13-E233 PolarHBondContact ND2-OE2 2.93Å; G231-E233 PolarHBondContact O-N 3.37Å; G231-E233 VanDerWaalsContact O-N 3.13Å
234Y82.2Confident84.2Confident89 Ų8934.8 Ų34.835%0.34917%0.169SC..G310 helixtrans-95.4-10.5-172.4-68.3-87.4000113.5N13 F14 V230 G231 V232 R236 M237 V238N13-Y234 HydrophobicContact CB-CD2 3.73Å; N13-Y234 HydrophobicContact CB-CE2 3.57Å; F14-Y234 HydrophobicContact CB-CD1 4.05Å; F14-Y234 HydrophobicContact CB-CD2 3.88Å; F14-Y234 HydrophobicContact CB-CE1 4.28Å; F14-Y234 HydrophobicContact CB-CE2 4.15Å; F14-Y234 HydrophobicContact CB-CG 3.84Å; F14-Y234 HydrophobicContact CD1-CD1 4.28Å; F14-Y234 HydrophobicContact CG-CD1 4.3Å; F14-Y234 HydrophobicContact CG-CG 4.31Å; V230-Y234 VanDerWaalsContact CG1-CB 3.45Å; G231-Y234 PolarHBondContact O-N 3.32Å; G231-Y234 VanDerWaalsContact O-N 3.07Å; V232-Y234 VanDerWaalsContact C-N 3.32Å; V232-Y234 PolarHBondContact O-N 3.04Å; Y234-R236 PolarHBondContact O-N 3.48Å; Y234-M237 HydrophobicContact CD1-CE 3.73Å; Y234-M237 HydrophobicContact CD1-SD 4.29Å; Y234-M237 HydrophobicContact CE1-CE 4.49Å; Y234-M237 PolarHBondContact O-N 2.92Å; Y234-M237 VanDerWaalsContact O-N 3.17Å; Y234-V238 WeakPolarHBondContact O-CB 3.46Å; Y234-V238 WeakPolarHBondContact O-CG2 3.41Å; Y234-V238 PolarHBondContact O-N 3.48Å
235R82.2Confident84.5Confident59 Ų5935.1 Ų35.122%0.22317%0.166CC..Hα-helixtrans-53.7-39.6179.8-70-173.3-175.8135.124.8112.6D5 T227 G231 V232 G239 R289D5-R235 IonicContact OD1-CZ 2.75Å; D5-R235 IonicContact OD1-NH2 2.77Å; D5-R235 PolarHBondContact OD1-NH2 3.31Å; T227-R235 PolarHBondContact O-NE 3.23Å; G231-R235 PolarHBondContact O-N 2.97Å; V232-R235 PolarHBondContact O-N 3.4Å; R235-G239 PolarHBondContact O-N 3.02Å; R235-R289 VanDerWaalsContact NH2-CZ 3.27Å
236R78.4Confident84.6Confident90 Ų9035.3 Ų35.334%0.3417%0.167SC..Hα-helixtrans-61.5-54.7177.3-67.5-172.9-72145.9-3.5111.6Y234 V238 G239 V240 D398 F451Y234-R236 PolarHBondContact O-N 3.48Å; R236-V238 VanDerWaalsContact C-N 3.27Å; R236-V238 PolarHBondContact O-N 3.16Å; R236-G239 PolarHBondContact O-N 3.47Å; R236-V240 WeakPolarHBondContact O-CG2 3.39Å; R236-V240 PolarHBondContact O-N 3.31Å; R236-V240 VanDerWaalsContact O-N 3.17Å; R236-D398 IonicContact CZ-OD1 3.78Å; R236-D398 IonicContact NH1-OD1 3.16Å; R236-D398 PolarHBondContact NH1-OD1 3.34Å; R236-D398 IonicContact NH1-OD2 3.63Å; R236-D398 IonicContact NH2-OD1 3.1Å; R236-F451 HydrophobicContact CB-CE1 4.2Å; R236-F451 HydrophobicContact CG-CD1 4.48Å; R236-F451 HydrophobicContact CG-CE1 4.09Å
237M82.9Confident84.7Confident65 Ų6535.2 Ų35.232%0.3217%0.167SC..Hα-helixtrans-57.3-43.2179.9-177.6-170.776.600111.5F14 Y234 V240 L241F14-M237 HydrophobicContact CD1-CE 4.05Å; F14-M237 HydrophobicContact CE1-CE 3.7Å; F14-M237 HydrophobicContact CZ-CE 4.23Å; Y234-M237 HydrophobicContact CD1-CE 3.73Å; Y234-M237 HydrophobicContact CD1-SD 4.29Å; Y234-M237 HydrophobicContact CE1-CE 4.49Å; Y234-M237 PolarHBondContact O-N 2.92Å; Y234-M237 VanDerWaalsContact O-N 3.17Å; M237-V240 PolarHBondContact O-N 3.42Å; M237-L241 HydrophobicContact CE-CD1 4.1Å; M237-L241 HydrophobicContact CG-CD1 3.86Å; M237-L241 HydrophobicContact CG-CG 4.38Å; M237-L241 WeakPolarHBondContact O-CB 3.35Å; M237-L241 VanDerWaalsContact O-CG 3.29Å; M237-L241 WeakPolarHBondContact O-CG 3.01Å; M237-L241 PolarHBondContact O-N 3.37Å; M237-L241 HydrophobicContact SD-CD1 4.39Å
238V85.7Confident85.2Confident2 Ų236.5 Ų36.51%0.01218%0.175CC..Hα-helixtrans-65.3-38.7-179.2157.20000112.5F14 F22 I226 V230 Y234 R236 L242F14-V238 HydrophobicContact CE2-CG2 3.88Å; F14-V238 HydrophobicContact CZ-CG2 4.13Å; F22-V238 HydrophobicContact CD2-CG1 3.82Å; F22-V238 HydrophobicContact CD2-CG2 4.24Å; F22-V238 HydrophobicContact CE2-CB 4.1Å; F22-V238 HydrophobicContact CE2-CG1 3.55Å; F22-V238 HydrophobicContact CE2-CG2 4.14Å; F22-V238 HydrophobicContact CZ-CG1 4.45Å; F22-V238 HydrophobicContact CZ-CG2 4.46Å; I226-V238 HydrophobicContact CB-CG1 4.41Å; I226-V238 HydrophobicContact CG2-CB 4.44Å; I226-V238 HydrophobicContact CG2-CG1 3Å; V230-V238 HydrophobicContact CG1-CG2 4.24Å; V230-V238 HydrophobicContact CG2-CG2 4.44Å; Y234-V238 WeakPolarHBondContact O-CB 3.46Å; Y234-V238 WeakPolarHBondContact O-CG2 3.41Å; Y234-V238 PolarHBondContact O-N 3.48Å; R236-V238 VanDerWaalsContact C-N 3.27Å; R236-V238 PolarHBondContact O-N 3.16Å; V238-L242 WeakPolarHBondContact O-CB 3.33Å; V238-L242 PolarHBondContact O-N 2.96Å
239G82.8Confident85.7Confident12 Ų1235.3 Ų35.312%0.12417%0.17CC..Hα-helixtrans-62.4-47.6172.300000112.7R235 R236 L241 L242 Q243R235-G239 PolarHBondContact O-N 3.02Å; R236-G239 PolarHBondContact O-N 3.47Å; G239-L241 PolarHBondContact O-N 3.43Å; G239-L242 PolarHBondContact O-N 3.05Å; G239-Q243 PolarHBondContact O-N 3.3Å
240V84Confident86Confident3 Ų335.3 Ų35.32%0.01817%0.17CC..Hα-helixtrans-63.7-42.5177.5-176.10000111R236 M237 L242 Q243 M244 A390 L394 F451R236-V240 WeakPolarHBondContact O-CG2 3.39Å; R236-V240 PolarHBondContact O-N 3.31Å; R236-V240 VanDerWaalsContact O-N 3.17Å; M237-V240 PolarHBondContact O-N 3.42Å; V240-L242 PolarHBondContact O-N 3.38Å; V240-Q243 WeakPolarHBondContact O-CB 3.49Å; V240-Q243 PolarHBondContact O-N 3.49Å; V240-M244 HydrophobicContact CB-CE 4.4Å; V240-M244 HydrophobicContact CG1-CE 3.61Å; V240-M244 WeakPolarHBondContact O-CG 3.3Å; V240-M244 PolarHBondContact O-N 2.65Å; V240-A390 HydrophobicContact CG1-CB 3.95Å; V240-L394 HydrophobicContact CB-CD2 4.36Å; V240-L394 HydrophobicContact CG1-CD1 4.36Å; V240-L394 HydrophobicContact CG1-CD2 4.4Å; V240-L394 HydrophobicContact CG1-CG 4.27Å; V240-L394 HydrophobicContact CG2-CD2 4.04Å; V240-F451 HydrophobicContact CG2-CE2 4.05Å; V240-F451 HydrophobicContact CG2-CZ 3.81Å
241L87.3Confident86.4Confident48 Ų4837.1 Ų37.125%0.25118%0.179SC..Hα-helixtrans-63.5-39.9177.5-75.5170.9000112F22 M237 G239 Q243 M244 F245F22-L241 HydrophobicContact CE1-CB 4.05Å; F22-L241 HydrophobicContact CE1-CD1 3.93Å; F22-L241 HydrophobicContact CZ-CB 3.52Å; F22-L241 HydrophobicContact CZ-CD1 4.1Å; F22-L241 HydrophobicContact CZ-CG 4.48Å; M237-L241 HydrophobicContact CE-CD1 4.1Å; M237-L241 HydrophobicContact CG-CD1 3.86Å; M237-L241 HydrophobicContact CG-CG 4.38Å; M237-L241 WeakPolarHBondContact O-CB 3.35Å; M237-L241 VanDerWaalsContact O-CG 3.29Å; M237-L241 WeakPolarHBondContact O-CG 3.01Å; M237-L241 PolarHBondContact O-N 3.37Å; M237-L241 HydrophobicContact SD-CD1 4.39Å; G239-L241 PolarHBondContact O-N 3.43Å; L241-Q243 PolarHBondContact O-N 3.05Å; L241-M244 HydrophobicContact CD2-CE 3.6Å; L241-M244 HydrophobicContact CD2-SD 3.95Å; L241-M244 HydrophobicContact CG-CE 4.14Å; L241-M244 WeakPolarHBondContact O-CB 3.39Å; L241-M244 PolarHBondContact O-N 3.17Å; L241-M244 VanDerWaalsContact O-N 3.11Å; L241-F245 WeakPolarHBondContact O-CD2 3.48Å; L241-F245 PolarHBondContact O-N 3.04Å; L241-F245 VanDerWaalsContact O-N 3.12Å
242L87.4Confident87.1Confident4 Ų440.5 Ų40.52%0.02120%0.196CC..Hα-helixtrans-58.5-37.3175.5-173.369.6000111.6C26 S29 V222 Y223 I226 V238 G239 V240 F245 F246C26-L242 HydrophobicContact CB-CD1 4.49Å; S29-L242 VanDerWaalsContact OG-CD1 3.24Å; S29-L242 WeakPolarHBondContact OG-CD1 3.45Å; S29-L242 PolarHBondContact OG-O 2.8Å; V222-L242 HydrophobicContact CG1-CD1 4.35Å; Y223-L242 HydrophobicContact CD2-CD2 3.93Å; I226-L242 HydrophobicContact CD1-CD1 4.1Å; V238-L242 WeakPolarHBondContact O-CB 3.33Å; V238-L242 PolarHBondContact O-N 2.96Å; G239-L242 PolarHBondContact O-N 3.05Å; V240-L242 PolarHBondContact O-N 3.38Å; L242-F245 PolarHBondContact O-N 3.34Å; L242-F246 PolarHBondContact O-N 3.09Å
243Q86.4Confident88Confident32 Ų3237.5 Ų37.515%0.1518%0.178CC..Hα-helixtrans-70.4-39.9174.3-173.861.622.600112.2G239 V240 L241 F245 F246 S247 E447G239-Q243 PolarHBondContact O-N 3.3Å; V240-Q243 WeakPolarHBondContact O-CB 3.49Å; V240-Q243 PolarHBondContact O-N 3.49Å; L241-Q243 PolarHBondContact O-N 3.05Å; Q243-F245 PolarHBondContact O-N 3.23Å; Q243-F246 WeakPolarHBondContact O-CA 3.45Å; Q243-F246 VanDerWaalsContact O-CB 3.23Å; Q243-F246 WeakPolarHBondContact O-CB 3.3Å; Q243-F246 PolarHBondContact O-N 3.39Å; Q243-S247 PolarHBondContact O-N 3.04Å; Q243-S247 PolarHBondContact O-OG 3.27Å; Q243-E447 HydrophobicContact CG-CG 4.37Å; Q243-E447 WeakPolarHBondContact CG-OE1 3.29Å
244M89.7Confident88.7Confident27 Ų2732.1 Ų32.113%0.13315%0.153CC..Hα-helixtrans-58.5-35174.2-67.5-176.2-131.300112.2V240 L241 F246 S247 V248 A390 L394V240-M244 HydrophobicContact CB-CE 4.4Å; V240-M244 HydrophobicContact CG1-CE 3.61Å; V240-M244 WeakPolarHBondContact O-CG 3.3Å; V240-M244 PolarHBondContact O-N 2.65Å; L241-M244 HydrophobicContact CD2-CE 3.6Å; L241-M244 HydrophobicContact CD2-SD 3.95Å; L241-M244 HydrophobicContact CG-CE 4.14Å; L241-M244 WeakPolarHBondContact O-CB 3.39Å; L241-M244 PolarHBondContact O-N 3.17Å; L241-M244 VanDerWaalsContact O-N 3.11Å; M244-F246 VanDerWaalsContact C-N 3.33Å; M244-S247 WeakPolarHBondContact O-CB 3.28Å; M244-S247 PolarHBondContact O-N 2.82Å; M244-V248 WeakPolarHBondContact O-CG2 3.38Å; M244-V248 PolarHBondContact O-N 2.99Å; M244-A390 HydrophobicContact CE-CB 4.31Å; M244-A390 HydrophobicContact CG-CB 4.02Å; M244-L394 HydrophobicContact CE-CD1 4.25Å
245F92.8Very high89.2Confident56 Ų5633.1 Ų33.125%0.24616%0.164CC..Hα-helixtrans-66-35.8172.9-87.2-97.3000112.1C26 M27 L30 L241 L242 Q243 S247 V248 G249C26-F245 HydrophobicContact CB-CB 4.29Å; C26-F245 HydrophobicContact CB-CD1 3.82Å; C26-F245 HydrophobicContact CB-CD2 3.58Å; C26-F245 HydrophobicContact CB-CE1 3.96Å; C26-F245 HydrophobicContact CB-CE2 3.72Å; C26-F245 HydrophobicContact CB-CG 3.63Å; C26-F245 HydrophobicContact CB-CZ 3.91Å; M27-F245 HydrophobicContact CE-CE1 3.97Å; M27-F245 HydrophobicContact SD-CE1 4.14Å; L30-F245 HydrophobicContact CD2-CD1 4.11Å; L30-F245 WeakPolarHBondContact CD2-O 3.49Å; L30-F245 HydrophobicContact CG-CD1 4.49Å; L241-F245 WeakPolarHBondContact O-CD2 3.48Å; L241-F245 PolarHBondContact O-N 3.04Å; L241-F245 VanDerWaalsContact O-N 3.12Å; L242-F245 PolarHBondContact O-N 3.34Å; Q243-F245 PolarHBondContact O-N 3.23Å; F245-S247 VanDerWaalsContact C-N 3.31Å; F245-S247 PolarHBondContact O-N 2.82Å; F245-V248 PolarHBondContact O-N 2.98Å; F245-G249 PolarHBondContact O-N 2.92Å
246F91.8Very high89.8Confident5 Ų532.2 Ų32.22%0.02216%0.163CC..Hα-helixtrans-59.6-43.4170.6174.4-92.8000111.4F32 Y36 L242 Q243 M244 V248 G249 I250 Y361F32-F246 HydrophobicContact CB-CD2 4.43Å; F32-F246 AromaticContact CD1-CD2 3.41Å; F32-F246 HydrophobicContact CD1-CD2 3.41Å; F32-F246 VanDerWaalsContact CD1-CD2 3.41Å; F32-F246 AromaticContact CD1-CE2 3.58Å; F32-F246 HydrophobicContact CD1-CE2 3.58Å; F32-F246 AromaticContact CE1-CD2 3.92Å; F32-F246 HydrophobicContact CE1-CD2 3.92Å; F32-F246 AromaticContact CE1-CE2 3.79Å; F32-F246 HydrophobicContact CE1-CE2 3.79Å; F32-F246 HydrophobicContact CG-CD2 4.14Å; F32-F246 HydrophobicContact CG-CE2 4.15Å; Y36-F246 AromaticContact CD1-CZ 3.92Å; Y36-F246 HydrophobicContact CD1-CZ 3.92Å; L242-F246 PolarHBondContact O-N 3.09Å; Q243-F246 WeakPolarHBondContact O-CA 3.45Å; Q243-F246 VanDerWaalsContact O-CB 3.23Å; Q243-F246 WeakPolarHBondContact O-CB 3.3Å; Q243-F246 PolarHBondContact O-N 3.39Å; M244-F246 VanDerWaalsContact C-N 3.33Å; F246-V248 PolarHBondContact O-N 3.27Å; F246-G249 VanDerWaalsContact O-CA 3.3Å; F246-G249 WeakPolarHBondContact O-CA 3.22Å; F246-G249 PolarHBondContact O-N 3.36Å; F246-I250 HydrophobicContact CD1-CD1 4.17Å; F246-I250 HydrophobicContact CE1-CD1 3.7Å; F246-I250 HydrophobicContact CE1-CG1 4.21Å; F246-I250 HydrophobicContact CZ-CD1 4.42Å; F246-I250 PolarHBondContact O-N 3.11Å; F246-I250 VanDerWaalsContact O-N 3.07Å; F246-Y361 WeakPolarHBondContact CE1-OH 3.44Å
247S92Very high90.5Very high2 Ų228 Ų281%0.01415%0.148CC..Hα-helixtrans-63.6-39175.4-46.70000113Q243 M244 F245 G249 I250 L251 E386Q243-S247 PolarHBondContact O-N 3.04Å; Q243-S247 PolarHBondContact O-OG 3.27Å; M244-S247 WeakPolarHBondContact O-CB 3.28Å; M244-S247 PolarHBondContact O-N 2.82Å; F245-S247 VanDerWaalsContact C-N 3.31Å; F245-S247 PolarHBondContact O-N 2.82Å; S247-G249 PolarHBondContact O-N 3.25Å; S247-I250 WeakPolarHBondContact O-CB 3.48Å; S247-I250 PolarHBondContact O-N 2.85Å; S247-I250 VanDerWaalsContact O-N 3.15Å; S247-L251 PolarHBondContact O-N 3.09Å; S247-E386 VanDerWaalsContact CB-OE2 3.29Å; S247-E386 WeakPolarHBondContact CB-OE2 3.46Å; S247-E386 WeakPolarHBondContact OG-CB 3.26Å; S247-E386 PolarHBondContact OG-OE2 3.4Å
248V94.6Very high90.9Very high50 Ų5032.1 Ų32.130%0.30316%0.161SC..Hα-helixtrans-60.5-38.7170.4173.60000110.6L30 M244 F245 F246 I250 L251 I252 F387L30-V248 HydrophobicContact CD2-CB 4.03Å; L30-V248 HydrophobicContact CD2-CG1 3.88Å; M244-V248 WeakPolarHBondContact O-CG2 3.38Å; M244-V248 PolarHBondContact O-N 2.99Å; F245-V248 PolarHBondContact O-N 2.98Å; F246-V248 PolarHBondContact O-N 3.27Å; V248-I250 VanDerWaalsContact C-N 3.32Å; V248-I250 PolarHBondContact O-N 3.21Å; V248-L251 PolarHBondContact O-N 3.08Å; V248-I252 HydrophobicContact CG1-CD1 3.81Å; V248-I252 HydrophobicContact CG1-CG1 4.34Å; V248-I252 WeakPolarHBondContact O-CG1 3.48Å; V248-I252 PolarHBondContact O-N 3.39Å; V248-F387 HydrophobicContact CG2-CE1 3.79Å; V248-F387 HydrophobicContact CG2-CZ 3.71Å
249G94.4Very high91.3Very high2 Ų238 Ų382%0.02119%0.191CC..Hα-helixtrans-56.4-43.3172.800000112.7S33 F245 F246 S247 L251 I252 L253S33-G249 WeakPolarHBondContact OG-CA 3.08Å; S33-G249 PolarHBondContact OG-O 3.45Å; F245-G249 PolarHBondContact O-N 2.92Å; F246-G249 VanDerWaalsContact O-CA 3.3Å; F246-G249 WeakPolarHBondContact O-CA 3.22Å; F246-G249 PolarHBondContact O-N 3.36Å; S247-G249 PolarHBondContact O-N 3.25Å; G249-L251 VanDerWaalsContact C-N 3.33Å; G249-L251 PolarHBondContact O-N 3.28Å; G249-I252 PolarHBondContact O-N 2.97Å; G249-L253 WeakPolarHBondContact O-CB 3.3Å; G249-L253 PolarHBondContact O-N 3.25Å
250I92.4Very high91.8Very high5 Ų539.8 Ų39.83%0.02620%0.198CC..Hα-helixtrans-59.6-42.8176.2-63.3178.6000111.1S33 V37 F246 S247 V248 L253 T254 F379 E386S33-I250 PolarHBondContact OG-N 2.83Å; V37-I250 HydrophobicContact CG2-CG1 4.24Å; F246-I250 HydrophobicContact CD1-CD1 4.17Å; F246-I250 HydrophobicContact CE1-CD1 3.7Å; F246-I250 HydrophobicContact CE1-CG1 4.21Å; F246-I250 HydrophobicContact CZ-CD1 4.42Å; F246-I250 PolarHBondContact O-N 3.11Å; F246-I250 VanDerWaalsContact O-N 3.07Å; S247-I250 WeakPolarHBondContact O-CB 3.48Å; S247-I250 PolarHBondContact O-N 2.85Å; S247-I250 VanDerWaalsContact O-N 3.15Å; V248-I250 VanDerWaalsContact C-N 3.32Å; V248-I250 PolarHBondContact O-N 3.21Å; I250-L253 WeakPolarHBondContact O-CB 3.46Å; I250-L253 PolarHBondContact O-N 2.98Å; I250-T254 PolarHBondContact O-N 3.12Å; I250-T254 PolarHBondContact O-OG1 2.99Å; I250-F379 HydrophobicContact CB-CE1 4.5Å; I250-F379 HydrophobicContact CG2-CD1 3.83Å; I250-F379 HydrophobicContact CG2-CE1 3.37Å; I250-F379 HydrophobicContact CG2-CZ 4.19Å; I250-E386 WeakPolarHBondContact CD1-OE1 3.48Å
251L94.6Very high92Very high40 Ų4042.5 Ų42.521%0.20921%0.214CC..Hα-helixtrans-65.3-45.7177.5-60.2-178.8000111.6S247 V248 G249 L253 T254 L255 L380 L384 F387S247-L251 PolarHBondContact O-N 3.09Å; V248-L251 PolarHBondContact O-N 3.08Å; G249-L251 VanDerWaalsContact C-N 3.33Å; G249-L251 PolarHBondContact O-N 3.28Å; L251-L253 VanDerWaalsContact C-N 3.33Å; L251-L253 PolarHBondContact O-N 2.91Å; L251-T254 WeakPolarHBondContact O-CB 3.21Å; L251-T254 PolarHBondContact O-N 3Å; L251-L255 PolarHBondContact O-N 3.47Å; L251-L380 HydrophobicContact CD2-CD1 3.82Å; L251-L384 HydrophobicContact CD1-CD2 4.19Å; L251-L384 HydrophobicContact CD2-CD2 4.2Å; L251-L384 HydrophobicContact CD2-CG 4.09Å; L251-F387 HydrophobicContact CD1-CE2 3.62Å; L251-F387 HydrophobicContact CD1-CZ 3.85Å; L251-F387 HydrophobicContact CG-CE2 4.25Å
252I94.8Very high92.2Very high73 Ų7342.9 Ų42.937%0.37422%0.217SC..Hα-helixtrans-62.6-43177.2-67.5170.5000110.4L30 V248 G249 T254 L255 I256L30-I252 HydrophobicContact CD1-CD1 4.44Å; L30-I252 HydrophobicContact CD2-CD1 4.28Å; V248-I252 HydrophobicContact CG1-CD1 3.81Å; V248-I252 HydrophobicContact CG1-CG1 4.34Å; V248-I252 WeakPolarHBondContact O-CG1 3.48Å; V248-I252 PolarHBondContact O-N 3.39Å; G249-I252 PolarHBondContact O-N 2.97Å; I252-T254 VanDerWaalsContact C-N 3.29Å; I252-T254 PolarHBondContact O-N 3.44Å; I252-L255 WeakPolarHBondContact O-CB 3.29Å; I252-L255 PolarHBondContact O-N 3.29Å; I252-I256 HydrophobicContact CG2-CD1 3.62Å; I252-I256 HydrophobicContact CG2-CG1 4.19Å; I252-I256 WeakPolarHBondContact O-CG1 3.47Å; I252-I256 PolarHBondContact O-N 2.87Å
253L93.8Very high92.5Very high3 Ų342.8 Ų42.82%0.01622%0.216CC..Hα-helixtrans-55.2-46176166.765.7000111.3V37 F41 G249 I250 L251 L255 I256 A257 F270 F379V37-L253 HydrophobicContact CG2-CD2 3.5Å; F41-L253 HydrophobicContact CD2-CD1 4.33Å; F41-L253 HydrophobicContact CD2-CD2 4.37Å; F41-L253 HydrophobicContact CD2-CG 4.2Å; F41-L253 HydrophobicContact CE2-CD2 4.15Å; F41-L253 HydrophobicContact CE2-CG 3.98Å; G249-L253 WeakPolarHBondContact O-CB 3.3Å; G249-L253 PolarHBondContact O-N 3.25Å; I250-L253 WeakPolarHBondContact O-CB 3.46Å; I250-L253 PolarHBondContact O-N 2.98Å; L251-L253 VanDerWaalsContact C-N 3.33Å; L251-L253 PolarHBondContact O-N 2.91Å; L253-L255 VanDerWaalsContact C-N 3.3Å; L253-L255 PolarHBondContact O-N 3.16Å; L253-I256 PolarHBondContact O-N 3.39Å; L253-A257 VanDerWaalsContact O-CB 3.28Å; L253-A257 WeakPolarHBondContact O-CB 3.22Å; L253-A257 PolarHBondContact O-N 3.38Å; L253-F270 HydrophobicContact CD1-CE1 3.37Å; L253-F270 HydrophobicContact CD1-CE2 4.03Å; L253-F270 HydrophobicContact CD1-CZ 3.05Å; L253-F379 HydrophobicContact CD2-CE1 4.04Å; L253-F379 HydrophobicContact CD2-CZ 4.23Å
254T92.8Very high92.9Very high7 Ų744.2 Ų44.24%0.04322%0.22CC..Hα-helixtrans-59.4-43.7179.6-49.40000111.2F41 I250 L251 I252 Y258 Y376 F379 L380F41-T254 HydrophobicContact CZ-CG2 4.36Å; I250-T254 PolarHBondContact O-N 3.12Å; I250-T254 PolarHBondContact O-OG1 2.99Å; L251-T254 WeakPolarHBondContact O-CB 3.21Å; L251-T254 PolarHBondContact O-N 3Å; I252-T254 VanDerWaalsContact C-N 3.29Å; I252-T254 PolarHBondContact O-N 3.44Å; T254-Y258 PolarHBondContact O-N 2.82Å; T254-Y258 VanDerWaalsContact O-N 3.09Å; T254-Y376 HydrophobicContact CG2-CD1 4.44Å; T254-Y376 WeakPolarHBondContact CG2-O 3.43Å; T254-F379 VanDerWaalsContact OG1-CD1 3.3Å; T254-F379 WeakPolarHBondContact OG1-CD1 3.35Å; T254-L380 HydrophobicContact CG2-CB 4.28Å
255L93.6Very high93.2Very high110 Ų11050.8 Ų50.858%0.57624%0.243SC*.Hα-helixtrans-65.5-45177179.662.8000111.8L251 I252 L253 Y258 L259L251-L255 PolarHBondContact O-N 3.47Å; I252-L255 WeakPolarHBondContact O-CB 3.29Å; I252-L255 PolarHBondContact O-N 3.29Å; L253-L255 VanDerWaalsContact C-N 3.3Å; L253-L255 PolarHBondContact O-N 3.16Å; L255-Y258 WeakPolarHBondContact O-CB 3.28Å; L255-Y258 PolarHBondContact O-N 3.03Å; L255-L259 HydrophobicContact CD1-CD1 4.48Å; L255-L259 HydrophobicContact CG-CD1 4.4Å; L255-L259 WeakPolarHBondContact O-CG 3.02Å; L255-L259 PolarHBondContact O-N 3.21Å
256I94.4Very high93.3Very high41 Ų4148.3 Ų48.321%0.2123%0.233CC..Hα-helixtrans-63.6-43.5178.7-66.3172.4000110.6I252 L253 Y258 L259 I260 L266 T269I252-I256 HydrophobicContact CG2-CD1 3.62Å; I252-I256 HydrophobicContact CG2-CG1 4.19Å; I252-I256 WeakPolarHBondContact O-CG1 3.47Å; I252-I256 PolarHBondContact O-N 2.87Å; L253-I256 PolarHBondContact O-N 3.39Å; I256-Y258 PolarHBondContact O-N 3.28Å; I256-L259 PolarHBondContact O-N 3.08Å; I256-L259 VanDerWaalsContact O-N 3.11Å; I256-I260 HydrophobicContact CG2-CD1 3.89Å; I256-I260 HydrophobicContact CG2-CG1 4.42Å; I256-I260 PolarHBondContact O-N 3.25Å; I256-L266 HydrophobicContact CG2-CD1 3.7Å; I256-T269 HydrophobicContact CD1-CG2 4.09Å; I256-T269 HydrophobicContact CG2-CG2 3.86Å
257A92.6Very high93.5Very high2 Ų248 Ų482%0.01723%0.232CC..Hα-helixtrans-67.3-23.3178.800000113.1F41 L253 L266 Y376F41-A257 HydrophobicContact CB-CB 3.98Å; F41-A257 HydrophobicContact CD1-CB 3.64Å; F41-A257 HydrophobicContact CD2-CB 3.82Å; F41-A257 HydrophobicContact CE1-CB 4.03Å; F41-A257 HydrophobicContact CE2-CB 4.2Å; F41-A257 HydrophobicContact CG-CB 3.52Å; F41-A257 HydrophobicContact CZ-CB 4.3Å; L253-A257 VanDerWaalsContact O-CB 3.28Å; L253-A257 WeakPolarHBondContact O-CB 3.22Å; L253-A257 PolarHBondContact O-N 3.38Å; A257-L266 HydrophobicContact CB-CD1 4.21Å; A257-L266 HydrophobicContact CB-CD2 4.14Å; A257-Y376 VanDerWaalsContact C-CE1 3.43Å; A257-Y376 HydrophobicContact CB-CE1 4.04Å; A257-Y376 VanDerWaalsContact O-CE1 3.29Å; A257-Y376 WeakPolarHBondContact O-CE1 3.38Å; A257-Y376 PolarHBondContact O-OH 3.27Å; A257-Y376 VanDerWaalsContact O-OH 3.04Å
258Y91.8Very high93.7Very high150 Ų15049.7 Ų49.759%0.58824%0.241SC*.Hα-helixtrans-74.9-35.6171.4179.9-100.8000111.7T254 L255 I256 Y376T254-Y258 PolarHBondContact O-N 2.82Å; T254-Y258 VanDerWaalsContact O-N 3.09Å; L255-Y258 WeakPolarHBondContact O-CB 3.28Å; L255-Y258 PolarHBondContact O-N 3.03Å; I256-Y258 PolarHBondContact O-N 3.28Å; Y258-Y376 HydrophobicContact CD2-CD1 4.4Å; Y258-Y376 HydrophobicContact CD2-CD2 4.08Å; Y258-Y376 HydrophobicContact CD2-CE2 4.21Å; Y258-Y376 HydrophobicContact CD2-CG 4.17Å
259L93.2Very high93.7Very high126 Ų12649.5 Ų49.566%0.6624%0.24SC*.Hα-helixtrans-82.6-32.5-179.9-64.3173.7000113.3L255 I256L255-L259 HydrophobicContact CD1-CD1 4.48Å; L255-L259 HydrophobicContact CG-CD1 4.4Å; L255-L259 WeakPolarHBondContact O-CG 3.02Å; L255-L259 PolarHBondContact O-N 3.21Å; I256-L259 PolarHBondContact O-N 3.08Å; I256-L259 VanDerWaalsContact O-N 3.11Å
260I93.3Very high93.6Very high49 Ų4949.8 Ų49.825%0.25124%0.241SC..  trans-114.6104.6-177.8-55.2178.4000108.3I256 W265 L266I256-I260 HydrophobicContact CG2-CD1 3.89Å; I256-I260 HydrophobicContact CG2-CG1 4.42Å; I256-I260 PolarHBondContact O-N 3.25Å; I260-W265 HydrophobicContact CG2-CB 3.71Å; I260-L266 HydrophobicContact CG2-CB 4.29Å
261T88.3Confident93.7Very high61 Ų6149.6 Ų49.637%0.37424%0.24SC..  trans-87.1-15.5-178.254.20000113.7G132 R133 Q134G132-T261 VanDerWaalsContact O-CB 3.31Å; G132-T261 WeakPolarHBondContact O-CB 3.43Å; G132-T261 PolarHBondContact O-OG1 2.98Å; R133-T261 HydrophobicContact CG-CG2 4.22Å; Q134-T261 PolarHBondContact N-O 3.38Å
262D92.6Very high93.7Very high55 Ų5550.9 Ų50.929%0.29425%0.25SC..BIsolated β-bridgetrans-84.4118.4175.8-69.2-41000111.7Q134 R264 W265 L266Q134-D262 PolarHBondContact OE1-OD1 3.03Å; D262-R264 VanDerWaalsContact C-N 3.27Å; D262-R264 PolarHBondContact O-N 3.45Å; D262-W265 HydrophobicContact CB-CB 4.36Å; D262-W265 PolarHBondContact O-N 3.27Å; D262-L266 WeakPolarHBondContact O-CB 3.36Å; D262-L266 PolarHBondContact O-N 3.45Å
263W93.5Very high93.7Very high3 Ų349.1 Ų49.11%0.01124%0.243CC..Hα-helixtrans-60-32.5-177.674.9-89000114Q42 Q134 F136 E139 F140 M204 Q267Q42-W263 HydrophobicContact CB-CB 4.27Å; Q42-W263 HydrophobicContact CG-CB 4.35Å; Q134-W263 WeakPolarHBondContact O-CB 3.24Å; Q134-W263 PolarHBondContact O-N 3.12Å; F136-W263 HydrophobicContact CB-CD2 3.89Å; F136-W263 HydrophobicContact CB-CE3 4.2Å; F136-W263 HydrophobicContact CB-CG 4.44Å; F136-W263 HydrophobicContact CB-CH2 4.2Å; F136-W263 HydrophobicContact CB-CZ2 3.88Å; F136-W263 HydrophobicContact CB-CZ3 4.35Å; E139-W263 VanDerWaalsContact OE2-CE2 3.23Å; E139-W263 WeakPolarHBondContact OE2-CZ2 3.47Å; E139-W263 PolarHBondContact OE2-NE1 3.39Å; F140-W263 HydrophobicContact CE2-CH2 4.42Å; F140-W263 HydrophobicContact CE2-CZ2 4.23Å; M204-W263 HydrophobicContact SD-CH2 3.61Å; M204-W263 HydrophobicContact SD-CZ3 3.81Å; W263-Q267 WeakPolarHBondContact O-CB 3.47Å; W263-Q267 PolarHBondContact O-N 3.15Å
264R95.3Very high93.8Very high62 Ų6249.1 Ų49.123%0.23424%0.243CC..Hα-helixtrans-66.4-47.1178.5-67.7-175.4173.6-97.44.6111.4E139 A196 A198 D262 L266 Q267 V268E139-R264 IonicContact OE1-CZ 3.56Å; E139-R264 VanDerWaalsContact OE1-CZ 3.25Å; E139-R264 IonicContact OE1-NE 2.86Å; E139-R264 PolarHBondContact OE1-NE 3.4Å; E139-R264 VanDerWaalsContact OE1-NE 3.1Å; E139-R264 IonicContact OE1-NH2 2.74Å; E139-R264 PolarHBondContact OE1-NH2 2.85Å; E139-R264 IonicContact OE2-CZ 3.86Å; E139-R264 IonicContact OE2-NE 3.96Å; E139-R264 PolarHBondContact OE2-NE 3.44Å; E139-R264 VanDerWaalsContact OE2-NE 3.16Å; E139-R264 IonicContact OE2-NH2 3.05Å; A196-R264 WeakPolarHBondContact O-CD 3.14Å; A196-R264 WeakPolarHBondContact O-CG 3.48Å; A196-R264 PolarHBondContact O-NH1 3.46Å; A198-R264 PolarHBondContact O-NH1 3.04Å; A198-R264 VanDerWaalsContact O-NH1 3.12Å; A198-R264 PolarHBondContact O-NH2 3.47Å; D262-R264 VanDerWaalsContact C-N 3.27Å; D262-R264 PolarHBondContact O-N 3.45Å; R264-L266 VanDerWaalsContact C-N 3.35Å; R264-Q267 WeakPolarHBondContact O-CB 3.41Å; R264-Q267 PolarHBondContact O-N 3.38Å; R264-V268 WeakPolarHBondContact O-CG2 3.23Å; R264-V268 PolarHBondContact O-N 2.85Å
265W95.4Very high93.9Very high164 Ų16452.1 Ų52.162%0.62126%0.255SS*.Hα-helixtrans-68.9-35.2176.6-75.4111.2000112.4I260 D262 Q267 V268 T269I260-W265 HydrophobicContact CG2-CB 3.71Å; D262-W265 HydrophobicContact CB-CB 4.36Å; D262-W265 PolarHBondContact O-N 3.27Å; W265-Q267 VanDerWaalsContact C-N 3.31Å; W265-Q267 PolarHBondContact O-N 3.16Å; W265-V268 PolarHBondContact O-N 3.36Å; W265-T269 PolarHBondContact O-N 3.48Å; W265-T269 PolarHBondContact O-OG1 3.44Å
266L95Very high93.9Very high4 Ų451.8 Ų51.82%0.02125%0.253CS..Hα-helixtrans-59.4-44.7172.4-172.860.9000110.8F41 Q42 I256 A257 I260 D262 R264 T269 F270F41-L266 HydrophobicContact CB-CD2 3.83Å; Q42-L266 HydrophobicContact CG-CD2 4.09Å; I256-L266 HydrophobicContact CG2-CD1 3.7Å; A257-L266 HydrophobicContact CB-CD1 4.21Å; A257-L266 HydrophobicContact CB-CD2 4.14Å; I260-L266 HydrophobicContact CG2-CB 4.29Å; D262-L266 WeakPolarHBondContact O-CB 3.36Å; D262-L266 PolarHBondContact O-N 3.45Å; R264-L266 VanDerWaalsContact C-N 3.35Å; L266-T269 WeakPolarHBondContact O-CB 3.24Å; L266-T269 PolarHBondContact O-N 3.3Å; L266-F270 HydrophobicContact CD1-CE1 4.01Å; L266-F270 HydrophobicContact CD1-CE2 4.27Å; L266-F270 HydrophobicContact CD1-CZ 3.45Å; L266-F270 VanDerWaalsContact CD1-CZ 3.45Å; L266-F270 HydrophobicContact CD2-CZ 4.29Å; L266-F270 HydrophobicContact CG-CE1 4.44Å; L266-F270 HydrophobicContact CG-CE2 3.82Å; L266-F270 HydrophobicContact CG-CZ 3.5Å; L266-F270 WeakPolarHBondContact O-CD2 3.38Å; L266-F270 WeakPolarHBondContact O-CE2 3.42Å; L266-F270 PolarHBondContact O-N 3.05Å
267Q95.3Very high93.9Very high0 Ų050.5 Ų50.50%025%0.246CC..Hα-helixtrans-62-43.3174.9179.363.514.900112.9G192 V195 A196 W263 R264 W265 T269 F270 A271G192-Q267 WeakPolarHBondContact O-CG 3.43Å; G192-Q267 PolarHBondContact O-NE2 2.95Å; V195-Q267 HydrophobicContact CB-CG 4.17Å; V195-Q267 HydrophobicContact CG1-CG 3.94Å; A196-Q267 HydrophobicContact CB-CB 4.03Å; A196-Q267 HydrophobicContact CB-CG 3.8Å; W263-Q267 WeakPolarHBondContact O-CB 3.47Å; W263-Q267 PolarHBondContact O-N 3.15Å; R264-Q267 WeakPolarHBondContact O-CB 3.41Å; R264-Q267 PolarHBondContact O-N 3.38Å; W265-Q267 VanDerWaalsContact C-N 3.31Å; W265-Q267 PolarHBondContact O-N 3.16Å; Q267-T269 VanDerWaalsContact C-N 3.26Å; Q267-T269 PolarHBondContact O-N 2.82Å; Q267-F270 PolarHBondContact O-N 3.27Å; Q267-A271 PolarHBondContact O-N 3.45Å; Q267-A271 VanDerWaalsContact O-N 3.16Å
268V96.3Very high94Very high36 Ų3652.9 Ų52.922%0.21826%0.258CS..Hα-helixtrans-59.7-40.1175.81730000111A196 R264 W265 F270 A271 V272A196-V268 HydrophobicContact CB-CG2 3.6Å; R264-V268 WeakPolarHBondContact O-CG2 3.23Å; R264-V268 PolarHBondContact O-N 2.85Å; W265-V268 PolarHBondContact O-N 3.36Å; V268-F270 PolarHBondContact O-N 3.34Å; V268-A271 PolarHBondContact O-N 3.48Å; V268-V272 HydrophobicContact CG1-CG2 3.84Å; V268-V272 WeakPolarHBondContact O-CG2 3.41Å; V268-V272 PolarHBondContact O-N 3.37Å
269T94.8Very high94.1Very high46 Ų4649.2 Ų49.228%0.28225%0.251SS..Hα-helixtrans-60.4-33.6179.6-570000112.2I256 W265 L266 Q267 P273I256-T269 HydrophobicContact CD1-CG2 4.09Å; I256-T269 HydrophobicContact CG2-CG2 3.86Å; W265-T269 PolarHBondContact O-N 3.48Å; W265-T269 PolarHBondContact O-OG1 3.44Å; L266-T269 WeakPolarHBondContact O-CB 3.24Å; L266-T269 PolarHBondContact O-N 3.3Å; Q267-T269 VanDerWaalsContact C-N 3.26Å; Q267-T269 PolarHBondContact O-N 2.82Å; T269-P273 WeakPolarHBondContact O-CD 3.31Å
270F91.5Very high94Very high9 Ų944.1 Ų44.14%0.03922%0.223CC..Hα-helixtrans-77.8-31.3174.3-49.9-34.6000113L253 L266 Q267 V268 Y274L253-F270 HydrophobicContact CD1-CE1 3.37Å; L253-F270 HydrophobicContact CD1-CE2 4.03Å; L253-F270 HydrophobicContact CD1-CZ 3.05Å; L266-F270 HydrophobicContact CD1-CE1 4.01Å; L266-F270 HydrophobicContact CD1-CE2 4.27Å; L266-F270 HydrophobicContact CD1-CZ 3.45Å; L266-F270 VanDerWaalsContact CD1-CZ 3.45Å; L266-F270 HydrophobicContact CD2-CZ 4.29Å; L266-F270 HydrophobicContact CG-CE1 4.44Å; L266-F270 HydrophobicContact CG-CE2 3.82Å; L266-F270 HydrophobicContact CG-CZ 3.5Å; L266-F270 WeakPolarHBondContact O-CD2 3.38Å; L266-F270 WeakPolarHBondContact O-CE2 3.42Å; L266-F270 PolarHBondContact O-N 3.05Å; Q267-F270 PolarHBondContact O-N 3.27Å; V268-F270 PolarHBondContact O-N 3.34Å; F270-Y274 VanDerWaalsContact O-CD2 3.24Å; F270-Y274 WeakPolarHBondContact O-CD2 3.27Å; F270-Y274 VanDerWaalsContact O-CE2 3.23Å; F270-Y274 WeakPolarHBondContact O-CE2 2.99Å
271A94.8Very high93.9Very high0 Ų046.6 Ų46.60%023%0.232CC..Hα-helixtrans-75.2-40.1-177.600000112.8I193 Q267 V268 Y274I193-A271 HydrophobicContact CG1-CB 4.14Å; Q267-A271 PolarHBondContact O-N 3.45Å; Q267-A271 VanDerWaalsContact O-N 3.16Å; V268-A271 PolarHBondContact O-N 3.48Å; A271-Y274 WeakPolarHBondContact O-CB 3.49Å; A271-Y274 PolarHBondContact O-N 2.95Å
272V95.1Very high94Very high68 Ų6854 Ų5441%0.41225%0.254SS..Hα-helixtrans-58-45-173.9168.30000114V268 Y274 F275V268-V272 HydrophobicContact CG1-CG2 3.84Å; V268-V272 WeakPolarHBondContact O-CG2 3.41Å; V268-V272 PolarHBondContact O-N 3.37Å; V272-Y274 PolarHBondContact O-N 2.82Å; V272-Y274 VanDerWaalsContact O-N 3.1Å; V272-F275 PolarHBondContact O-N 3.4Å
273P95Very high93.9Very high35 Ų3555.5 Ų55.523%0.22726%0.261CS..Hα-helixtrans-54.6-30.7178.3-29.436.2000114.3P31 T269 F275 I276 F277P31-P273 HydrophobicContact CB-CB 4.35Å; P31-P273 HydrophobicContact CG-CB 4.19Å; T269-P273 WeakPolarHBondContact O-CD 3.31Å; P273-F275 VanDerWaalsContact C-N 3.27Å; P273-F275 PolarHBondContact O-N 2.95Å; P273-I276 WeakPolarHBondContact O-CB 3.16Å; P273-I276 PolarHBondContact O-N 3.06Å; P273-F277 HydrophobicContact CB-CE2 4.23Å; P273-F277 HydrophobicContact CB-CZ 4.22Å; P273-F277 WeakPolarHBondContact O-CD2 3.46Å; P273-F277 WeakPolarHBondContact O-CG 3.35Å; P273-F277 PolarHBondContact O-N 2.62Å; P273-F277 VanDerWaalsContact O-N 3.15Å
274Y95.1Very high93.8Very high4 Ų455.7 Ų55.72%0.01626%0.262CS..Hα-helixtrans-64.3-29.6179.1-67.7-71.4000113.3P31 F32 V35 N185 N188 F211 F270 A271 V272 F277P31-Y274 HydrophobicContact CB-CE2 3.94Å; P31-Y274 HydrophobicContact CG-CE1 4.14Å; P31-Y274 HydrophobicContact CG-CE2 4.27Å; F32-Y274 PolarHBondContact N-OH 3.27Å; V35-Y274 HydrophobicContact CG2-CE2 4.16Å; N185-Y274 WeakPolarHBondContact OD1-CD1 2.95Å; N188-Y274 HydrophobicContact CB-CD1 3.83Å; N188-Y274 HydrophobicContact CB-CD2 3.94Å; N188-Y274 HydrophobicContact CB-CE1 4.23Å; N188-Y274 HydrophobicContact CB-CE2 4.33Å; N188-Y274 HydrophobicContact CB-CG 3.68Å; F211-Y274 HydrophobicContact CE2-CD2 4.47Å; F211-Y274 HydrophobicContact CE2-CE2 4.09Å; F211-Y274 HydrophobicContact CZ-CE2 4.15Å; F270-Y274 VanDerWaalsContact O-CD2 3.24Å; F270-Y274 WeakPolarHBondContact O-CD2 3.27Å; F270-Y274 VanDerWaalsContact O-CE2 3.23Å; F270-Y274 WeakPolarHBondContact O-CE2 2.99Å; A271-Y274 WeakPolarHBondContact O-CB 3.49Å; A271-Y274 PolarHBondContact O-N 2.95Å; V272-Y274 PolarHBondContact O-N 2.82Å; V272-Y274 VanDerWaalsContact O-N 3.1Å; Y274-F277 HydrophobicContact CD1-CD2 4.03Å; Y274-F277 HydrophobicContact CD1-CE2 4.31Å; Y274-F277 PolarHBondContact O-N 3.27Å
275F95.6Very high93.6Very high70 Ų7054.1 Ų54.131%0.30726%0.26SS..Hα-helixtrans-70.7-35.3172.7-66.6-75.5000112.1L186 G189 V190 I193 V272 P273 F277 L278L186-F275 HydrophobicContact CD1-CE1 4.37Å; G189-F275 VanDerWaalsContact C-CE2 3.49Å; G189-F275 VanDerWaalsContact CA-CE2 3.41Å; V190-F275 HydrophobicContact CG2-CE1 4.32Å; V190-F275 HydrophobicContact CG2-CZ 4.3Å; I193-F275 HydrophobicContact CD1-CE2 3.5Å; I193-F275 HydrophobicContact CD1-CZ 3.84Å; I193-F275 HydrophobicContact CG1-CE2 4.36Å; V272-F275 PolarHBondContact O-N 3.4Å; P273-F275 VanDerWaalsContact C-N 3.27Å; P273-F275 PolarHBondContact O-N 2.95Å; F275-F277 VanDerWaalsContact C-N 3.26Å; F275-F277 PolarHBondContact O-N 2.87Å; F275-L278 HydrophobicContact CD1-CD1 4.16Å; F275-L278 VanDerWaalsContact O-CB 3.28Å; F275-L278 WeakPolarHBondContact O-CB 2.97Å; F275-L278 WeakPolarHBondContact O-CG 3.44Å; F275-L278 PolarHBondContact O-N 3.17Å; F275-L278 VanDerWaalsContact O-N 3.13Å
276I94Very high93.5Very high102 Ų10247.4 Ų47.452%0.52324%0.236SC..Hα-helixtrans-63.3-38.2176.1-56.4176.4000109.6P273 L278 T279P273-I276 WeakPolarHBondContact O-CB 3.16Å; P273-I276 PolarHBondContact O-N 3.06Å; I276-L278 PolarHBondContact O-N 3.05Å; I276-L278 VanDerWaalsContact O-N 3.15Å; I276-T279 WeakPolarHBondContact O-CB 3.33Å; I276-T279 WeakPolarHBondContact O-CG2 3.44Å; I276-T279 PolarHBondContact O-N 3.46Å; I276-T279 PolarHBondContact O-OG1 3.05Å
277F93.8Very high93.2Very high14 Ų1447.2 Ų47.26%0.06124%0.235CC..G310 helixtrans-65.9-13.5177.3-56.2-35.7000114.2M27 V28 P31 F181 N185 P273 Y274 F275 T279 Y280M27-F277 HydrophobicContact CB-CE1 4.18Å; M27-F277 HydrophobicContact CB-CZ 4.47Å; M27-F277 WeakPolarHBondContact O-CZ 3.36Å; V28-F277 HydrophobicContact CB-CD2 4.38Å; V28-F277 HydrophobicContact CB-CE2 4.17Å; V28-F277 HydrophobicContact CG1-CD2 4.22Å; V28-F277 HydrophobicContact CG1-CE2 4.21Å; V28-F277 HydrophobicContact CG2-CD1 4.27Å; V28-F277 HydrophobicContact CG2-CD2 3.94Å; V28-F277 HydrophobicContact CG2-CE1 4.39Å; V28-F277 HydrophobicContact CG2-CE2 4.07Å; V28-F277 HydrophobicContact CG2-CG 4.06Å; V28-F277 HydrophobicContact CG2-CZ 4.3Å; P31-F277 HydrophobicContact CG-CE2 3.71Å; P31-F277 HydrophobicContact CG-CZ 4.15Å; F181-F277 HydrophobicContact CZ-CB 4.35Å; N185-F277 WeakPolarHBondContact OD1-CD2 3.49Å; P273-F277 HydrophobicContact CB-CE2 4.23Å; P273-F277 HydrophobicContact CB-CZ 4.22Å; P273-F277 WeakPolarHBondContact O-CD2 3.46Å; P273-F277 WeakPolarHBondContact O-CG 3.35Å; P273-F277 PolarHBondContact O-N 2.62Å; P273-F277 VanDerWaalsContact O-N 3.15Å; Y274-F277 HydrophobicContact CD1-CD2 4.03Å; Y274-F277 HydrophobicContact CD1-CE2 4.31Å; Y274-F277 PolarHBondContact O-N 3.27Å; F275-F277 VanDerWaalsContact C-N 3.26Å; F275-F277 PolarHBondContact O-N 2.87Å; F277-T279 PolarHBondContact O-N 3.43Å; F277-Y280 HydrophobicContact CD1-CE1 4.15Å; F277-Y280 HydrophobicContact CD1-CE2 4.01Å; F277-Y280 AromaticContact CD1-CZ 3.76Å; F277-Y280 WeakPolarHBondContact O-CB 3.43Å; F277-Y280 PolarHBondContact O-N 2.92Å
278L94.1Very high92.8Very high53 Ų5347.2 Ų47.228%0.27724%0.235SC..G310 helixtrans-64.3-27.5170.6-60.2177.1000112.2L182 N185 L186 F275 I276 Y280 F281L182-L278 HydrophobicContact CD2-CD2 4.44Å; L182-L278 WeakPolarHBondContact O-CD2 3.39Å; N185-L278 HydrophobicContact CB-CD2 4.02Å; L186-L278 HydrophobicContact CB-CD2 4.03Å; L186-L278 HydrophobicContact CD1-CD1 4Å; F275-L278 HydrophobicContact CD1-CD1 4.16Å; F275-L278 VanDerWaalsContact O-CB 3.28Å; F275-L278 WeakPolarHBondContact O-CB 2.97Å; F275-L278 WeakPolarHBondContact O-CG 3.44Å; F275-L278 PolarHBondContact O-N 3.17Å; F275-L278 VanDerWaalsContact O-N 3.13Å; I276-L278 PolarHBondContact O-N 3.05Å; I276-L278 VanDerWaalsContact O-N 3.15Å; L278-Y280 PolarHBondContact O-N 3.33Å; L278-Y280 VanDerWaalsContact O-N 3.13Å; L278-F281 WeakPolarHBondContact O-CB 3.37Å; L278-F281 PolarHBondContact O-N 3.04Å
279T93.8Very high92.2Very high73 Ų7347.8 Ų47.845%0.44823%0.233SC..G310 helixtrans-63-17.3174670000112.5I276 F277 F281 W282I276-T279 WeakPolarHBondContact O-CB 3.33Å; I276-T279 WeakPolarHBondContact O-CG2 3.44Å; I276-T279 PolarHBondContact O-N 3.46Å; I276-T279 PolarHBondContact O-OG1 3.05Å; F277-T279 PolarHBondContact O-N 3.43Å; T279-F281 PolarHBondContact O-N 3.27Å; T279-F281 VanDerWaalsContact O-N 3.11Å; T279-W282 PolarHBondContact O-N 3.1Å; T279-W282 VanDerWaalsContact O-N 3.09Å
280Y92.6Very high91.8Very high19 Ų1946.9 Ų46.98%0.07523%0.225CC..Hα-helixtrans-68.6-10.7178.7-70.313.5000112.7L24 V28 F181 F277 L278 W282 L283 I284L24-Y280 HydrophobicContact CB-CE2 3.93Å; L24-Y280 HydrophobicContact CD2-CE1 4.26Å; L24-Y280 VanDerWaalsContact O-CE2 3.29Å; L24-Y280 WeakPolarHBondContact O-CE2 3.36Å; L24-Y280 PolarHBondContact O-OH 3.05Å; L24-Y280 VanDerWaalsContact O-OH 3.13Å; V28-Y280 HydrophobicContact CG2-CE2 4.27Å; F181-Y280 HydrophobicContact CE1-CD2 4.17Å; F181-Y280 HydrophobicContact CZ-CD2 4.17Å; F277-Y280 HydrophobicContact CD1-CE1 4.15Å; F277-Y280 HydrophobicContact CD1-CE2 4.01Å; F277-Y280 AromaticContact CD1-CZ 3.76Å; F277-Y280 WeakPolarHBondContact O-CB 3.43Å; F277-Y280 PolarHBondContact O-N 2.92Å; L278-Y280 PolarHBondContact O-N 3.33Å; L278-Y280 VanDerWaalsContact O-N 3.13Å; Y280-W282 PolarHBondContact O-N 3.46Å; Y280-W282 VanDerWaalsContact O-N 3.14Å; Y280-L283 HydrophobicContact CD1-CD1 3.89Å; Y280-L283 HydrophobicContact CE1-CD1 4.19Å; Y280-L283 PolarHBondContact O-N 2.99Å; Y280-L283 VanDerWaalsContact O-N 3.16Å; Y280-I284 HydrophobicContact CD2-CD1 3.47Å; Y280-I284 VanDerWaalsContact CD2-CD1 3.47Å; Y280-I284 HydrophobicContact CD2-CG1 4.45Å; Y280-I284 HydrophobicContact CE2-CD1 4.26Å; Y280-I284 HydrophobicContact CG-CD1 3.94Å; Y280-I284 HydrophobicContact CG-CG1 4.49Å; Y280-I284 PolarHBondContact O-N 3.26Å; Y280-I284 VanDerWaalsContact O-N 3.09Å
281F90.2Very high91.4Very high100 Ų10046.9 Ų46.944%0.43923%0.225SC..Hα-helixtrans-51-33.7166.3178.6-99.4000112.3K178 L182 L278 T279K178-F281 WeakPolarHBondContact CE-O 3.34Å; K178-F281 PolarHBondContact NZ-O 3.49Å; L182-F281 HydrophobicContact CD1-CB 3.71Å; L182-F281 HydrophobicContact CD1-CD2 3.48Å; L182-F281 VanDerWaalsContact CD1-CD2 3.48Å; L182-F281 HydrophobicContact CD1-CG 4.07Å; L182-F281 HydrophobicContact CD2-CB 4.19Å; L278-F281 WeakPolarHBondContact O-CB 3.37Å; L278-F281 PolarHBondContact O-N 3.04Å; T279-F281 PolarHBondContact O-N 3.27Å; T279-F281 VanDerWaalsContact O-N 3.11Å
282W90.8Very high90.9Very high217 Ų21747.5 Ų47.582%0.82223%0.228SC*.Hα-helixtrans-91.3-25-179.1-5690.5000113.3T279 Y280T279-W282 PolarHBondContact O-N 3.1Å; T279-W282 VanDerWaalsContact O-N 3.09Å; Y280-W282 PolarHBondContact O-N 3.46Å; Y280-W282 VanDerWaalsContact O-N 3.14Å
283L89.1Confident90.1Very high87 Ų8746.5 Ų46.546%0.45522%0.224SC..Hα-helixtrans-93.3-22.1-170.2-60.8173.6000113.6L24 Y280L24-L283 HydrophobicContact CD1-CB 3.98Å; L24-L283 HydrophobicContact CD1-CD1 4.28Å; Y280-L283 HydrophobicContact CD1-CD1 3.89Å; Y280-L283 HydrophobicContact CE1-CD1 4.19Å; Y280-L283 PolarHBondContact O-N 2.99Å; Y280-L283 VanDerWaalsContact O-N 3.16Å
284I91.8Very high89.4Confident6 Ų649.2 Ų49.23%0.03123%0.234CC..  trans-119.9131.2-168.9-55.6-172.8000110.8I21 L24 L25 K178 L225 Y280I21-I284 HydrophobicContact CG2-CG2 4.04Å; L24-I284 HydrophobicContact CB-CD1 4.5Å; L25-I284 HydrophobicContact CD1-CD1 4.3Å; L25-I284 HydrophobicContact CD2-CD1 3.31Å; L25-I284 HydrophobicContact CG-CD1 3.62Å; K178-I284 WeakPolarHBondContact CD-O 3.48Å; K178-I284 WeakPolarHBondContact CE-O 3.48Å; K178-I284 PolarHBondContact NZ-O 3.49Å; L225-I284 HydrophobicContact CD2-CG2 3.8Å; Y280-I284 HydrophobicContact CD2-CD1 3.47Å; Y280-I284 VanDerWaalsContact CD2-CD1 3.47Å; Y280-I284 HydrophobicContact CD2-CG1 4.45Å; Y280-I284 HydrophobicContact CE2-CD1 4.26Å; Y280-I284 HydrophobicContact CG-CD1 3.94Å; Y280-I284 HydrophobicContact CG-CG1 4.49Å; Y280-I284 PolarHBondContact O-N 3.26Å; Y280-I284 VanDerWaalsContact O-N 3.09Å
285P92.2Very high88.7Confident29 Ų2956 Ų5619%0.18827%0.271CS..PPolyproline II helixtrans-75.2161.9174.132.2-34.8000111.9I21 I303I21-P285 HydrophobicContact CD1-CG 3.73Å; P285-I303 HydrophobicContact CB-CD1 4.29Å; P285-I303 HydrophobicContact CB-CG1 4.47Å; P285-I303 HydrophobicContact CB-CG2 3.83Å; P285-I303 HydrophobicContact CG-CG2 4.39Å
286E92.6Very high88.2Confident23 Ų2355.3 Ų55.311%0.10727%0.27CS..PPolyproline II helixtrans-75158.7167.2-17359.4-86.100110.2R177 K178 P288 W290 L291R177-E286 PolarHBondContact N-OE1 3.38Å; K178-E286 VanDerWaalsContact CB-OE2 3.26Å; K178-E286 WeakPolarHBondContact CB-OE2 3.41Å; K178-E286 PolarHBondContact N-OE1 3.25Å; K178-E286 PolarHBondContact N-OE2 3.15Å; E286-P288 WeakPolarHBondContact O-CD 3.34Å; E286-W290 HydrophobicContact CG-CE3 3.76Å; E286-W290 HydrophobicContact CG-CZ3 4.12Å; E286-L291 HydrophobicContact CB-CD1 4.37Å; E286-L291 HydrophobicContact CG-CD1 4.5Å; E286-L291 HydrophobicContact CG-CD2 4.46Å; E286-L291 HydrophobicContact CG-CG 4.31Å
287S89.4Confident87.6Confident0 Ų052.6 Ų52.60%026%0.26CS..PPolyproline II helixtrans-62.1122.9177.4171.50000112.2E228 R289 W290 L291E228-S287 WeakPolarHBondContact OE2-CB 3.36Å; E228-S287 PolarHBondContact OE2-OG 3.46Å; S287-R289 VanDerWaalsContact C-N 3.28Å; S287-R289 PolarHBondContact O-N 3.38Å; S287-R289 PolarHBondContact OG-N 2.93Å; S287-W290 PolarHBondContact O-N 2.8Å; S287-W290 PolarHBondContact OG-N 3.42Å; S287-L291 WeakPolarHBondContact O-CG 3.31Å; S287-L291 PolarHBondContact O-N 2.66Å; S287-L291 VanDerWaalsContact O-N 3.11Å
288P87.1Confident87.2Confident1 Ų156.6 Ų56.61%0.00629%0.286CS..Hα-helixtrans-63.9-32.5174.9-21.432.9000112.8F4 L229 E286 L291 L292 I303 I304F4-P288 HydrophobicContact CE2-CB 3.78Å; F4-P288 HydrophobicContact CZ-CB 3.85Å; F4-P288 HydrophobicContact CZ-CG 4.48Å; L229-P288 HydrophobicContact CD2-CG 4.2Å; E286-P288 WeakPolarHBondContact O-CD 3.34Å; P288-L291 PolarHBondContact O-N 2.96Å; P288-L292 WeakPolarHBondContact O-CG 3.49Å; P288-L292 PolarHBondContact O-N 3.48Å; P288-L292 VanDerWaalsContact O-N 3.08Å; P288-I303 HydrophobicContact CG-CB 4.43Å; P288-I303 HydrophobicContact CG-CG2 3.8Å; P288-I304 HydrophobicContact CB-CD1 4.14Å; P288-I304 HydrophobicContact CB-CG1 3.95Å; P288-I304 HydrophobicContact CG-CG1 4.27Å
289R83Confident86.9Confident47 Ų4759.4 Ų59.418%0.17730%0.296CS..Hα-helixtrans-63.7-47.2176.1-66.1-174-161.6-131.9-25.3111.4F4 D5 E228 R235 S287 L291 L292 S293F4-R289 HydrophobicContact CD1-CG 3.47Å; F4-R289 VanDerWaalsContact CD1-CG 3.47Å; F4-R289 VanDerWaalsContact CD1-CZ 3.46Å; F4-R289 VanDerWaalsContact CD1-NE 3.33Å; F4-R289 HydrophobicContact CD2-CG 4.16Å; F4-R289 HydrophobicContact CE1-CG 3.21Å; F4-R289 VanDerWaalsContact CE1-NH2 3.34Å; F4-R289 HydrophobicContact CE2-CG 3.92Å; F4-R289 HydrophobicContact CG-CG 3.94Å; F4-R289 HydrophobicContact CZ-CG 3.45Å; F4-R289 VanDerWaalsContact CZ-CG 3.45Å; D5-R289 IonicContact OD1-CZ 2.61Å; D5-R289 IonicContact OD1-NH1 3.54Å; D5-R289 IonicContact OD1-NH2 2.91Å; D5-R289 PolarHBondContact OD1-NH2 3.21Å; D5-R289 IonicContact OD2-NH1 2.72Å; E228-R289 HydrophobicContact CB-CG 4.35Å; E228-R289 PolarHBondContact O-NE 3.32Å; E228-R289 VanDerWaalsContact O-NE 3.14Å; R235-R289 VanDerWaalsContact NH2-CZ 3.27Å; S287-R289 VanDerWaalsContact C-N 3.28Å; S287-R289 PolarHBondContact O-N 3.38Å; S287-R289 PolarHBondContact OG-N 2.93Å; R289-L291 VanDerWaalsContact C-N 3.29Å; R289-L291 PolarHBondContact O-N 3.48Å; R289-L292 PolarHBondContact O-N 2.83Å; R289-S293 PolarHBondContact O-N 3.2Å
290W85.4Confident86.5Confident28 Ų2855.9 Ų55.911%0.10627%0.274CS..Hα-helixtrans-58.7-43.2176.1-172.265.3000112.1D173 F175 G176 E286 S287 L292 S293 Q294D173-W290 PolarHBondContact O-NE1 3.45Å; F175-W290 VanDerWaalsContact C-CZ2 3.48Å; G176-W290 VanDerWaalsContact CA-CZ2 3.47Å; E286-W290 HydrophobicContact CG-CE3 3.76Å; E286-W290 HydrophobicContact CG-CZ3 4.12Å; S287-W290 PolarHBondContact O-N 2.8Å; S287-W290 PolarHBondContact OG-N 3.42Å; W290-L292 VanDerWaalsContact C-N 3.29Å; W290-L292 PolarHBondContact O-N 3.32Å; W290-S293 PolarHBondContact O-N 3.28Å; W290-S293 PolarHBondContact O-OG 3.04Å; W290-Q294 HydrophobicContact CD2-CG 3.99Å; W290-Q294 HydrophobicContact CE3-CG 4.39Å; W290-Q294 HydrophobicContact CH2-CG 4.06Å; W290-Q294 HydrophobicContact CZ2-CG 3.61Å; W290-Q294 HydrophobicContact CZ3-CG 4.43Å; W290-Q294 VanDerWaalsContact O-CG 3.3Å; W290-Q294 WeakPolarHBondContact O-CG 3.42Å; W290-Q294 PolarHBondContact O-N 2.92Å
291L84.8Confident86.2Confident9 Ų957.8 Ų57.85%0.04728%0.283CS..Hα-helixtrans-63.6-37.7-179.8-72.5169000111.5E286 S287 P288 R289 Q294 N295 N296 K299 A300 I303E286-L291 HydrophobicContact CB-CD1 4.37Å; E286-L291 HydrophobicContact CG-CD1 4.5Å; E286-L291 HydrophobicContact CG-CD2 4.46Å; E286-L291 HydrophobicContact CG-CG 4.31Å; S287-L291 WeakPolarHBondContact O-CG 3.31Å; S287-L291 PolarHBondContact O-N 2.66Å; S287-L291 VanDerWaalsContact O-N 3.11Å; P288-L291 PolarHBondContact O-N 2.96Å; R289-L291 VanDerWaalsContact C-N 3.29Å; R289-L291 PolarHBondContact O-N 3.48Å; L291-Q294 PolarHBondContact O-N 3.36Å; L291-N295 PolarHBondContact O-N 3.28Å; L291-N296 HydrophobicContact CD2-CB 4.28Å; L291-N296 CarbonylContact O-C 3.45Å; L291-N296 WeakPolarHBondContact O-CA 3.3Å; L291-N296 WeakPolarHBondContact O-CB 3.2Å; L291-N296 PolarHBondContact O-N 3.38Å; L291-K299 HydrophobicContact CD1-CB 4.03Å; L291-K299 HydrophobicContact CD2-CB 4.36Å; L291-A300 HydrophobicContact CB-CB 3.88Å; L291-I303 HydrophobicContact CD1-CD1 3.51Å
292L82.7Confident86.2Confident12 Ų1258.6 Ų58.66%0.06329%0.288CS..Hα-helixtrans-66.3-42.4173.5-69.4168.3000112F4 P288 R289 W290 Q294 N295 A300 L322F4-L292 HydrophobicContact CD2-CD1 3.42Å; F4-L292 VanDerWaalsContact CD2-CD1 3.42Å; F4-L292 HydrophobicContact CE2-CD1 3.84Å; P288-L292 WeakPolarHBondContact O-CG 3.49Å; P288-L292 PolarHBondContact O-N 3.48Å; P288-L292 VanDerWaalsContact O-N 3.08Å; R289-L292 PolarHBondContact O-N 2.83Å; W290-L292 VanDerWaalsContact C-N 3.29Å; W290-L292 PolarHBondContact O-N 3.32Å; L292-Q294 PolarHBondContact O-N 3.07Å; L292-N295 PolarHBondContact O-N 3.3Å; L292-A300 HydrophobicContact CD2-CB 3.91Å; L292-A300 HydrophobicContact CG-CB 3.82Å; L292-L322 HydrophobicContact CD1-CB 4.49Å; L292-L322 HydrophobicContact CD1-CD1 4.23Å; L292-L322 HydrophobicContact CD2-CB 4.23Å
293S78.5Confident86.1Confident48 Ų4849.8 Ų49.834%0.33626%0.257SS..Hα-helixtrans-64.6-25.3177.180.20000112.7R289 W290 N295 D324R289-S293 PolarHBondContact O-N 3.2Å; W290-S293 PolarHBondContact O-N 3.28Å; W290-S293 PolarHBondContact O-OG 3.04Å; S293-N295 VanDerWaalsContact C-N 3.33Å; S293-D324 VanDerWaalsContact CB-OD2 3.32Å; S293-D324 WeakPolarHBondContact CB-OD2 3.34Å
294Q80.6Confident86.1Confident92 Ų9245.8 Ų45.843%0.4324%0.236SC..THydrogen-bonded Turntrans-90.113.6174.5-63.2-64.3-20.200113.7D173 W290 L291 L292 N296D173-Q294 PolarHBondContact O-NE2 2.93Å; W290-Q294 HydrophobicContact CD2-CG 3.99Å; W290-Q294 HydrophobicContact CE3-CG 4.39Å; W290-Q294 HydrophobicContact CH2-CG 4.06Å; W290-Q294 HydrophobicContact CZ2-CG 3.61Å; W290-Q294 HydrophobicContact CZ3-CG 4.43Å; W290-Q294 VanDerWaalsContact O-CG 3.3Å; W290-Q294 WeakPolarHBondContact O-CG 3.42Å; W290-Q294 PolarHBondContact O-N 2.92Å; L291-Q294 PolarHBondContact O-N 3.36Å; L292-Q294 PolarHBondContact O-N 3.07Å; Q294-N296 PolarHBondContact O-N 2.99Å
295N81.4Confident85.9Confident147 Ų14749.9 Ų49.979%0.78626%0.255SS*.THydrogen-bonded Turntrans57.224.5-176-63.8-47.4000114.5L291 L292 S293 S297L291-N295 PolarHBondContact O-N 3.28Å; L292-N295 PolarHBondContact O-N 3.3Å; S293-N295 VanDerWaalsContact C-N 3.33Å; N295-S297 PolarHBondContact O-N 2.92Å
296N83.7Confident85.7Confident54 Ų5451.2 Ų51.229%0.28927%0.268SS..  trans-101.858.8178.6-159.1-21.9000111.6L291 Q294 T298 K299 A300L291-N296 HydrophobicContact CD2-CB 4.28Å; L291-N296 CarbonylContact O-C 3.45Å; L291-N296 WeakPolarHBondContact O-CA 3.3Å; L291-N296 WeakPolarHBondContact O-CB 3.2Å; L291-N296 PolarHBondContact O-N 3.38Å; Q294-N296 PolarHBondContact O-N 2.99Å; N296-T298 VanDerWaalsContact C-N 3.26Å; N296-T298 PolarHBondContact O-N 2.99Å; N296-K299 PolarHBondContact O-N 3.39Å; N296-A300 PolarHBondContact O-N 3.24Å
297S82.3Confident85.6Confident45 Ų4550.3 Ų50.332%0.31526%0.264SS..Hα-helixtrans-63.9-28.1-173.8-51.20000113.6N295 A300 K301N295-S297 PolarHBondContact O-N 2.92Å; S297-A300 PolarHBondContact O-N 2.84Å; S297-K301 WeakPolarHBondContact O-CB 3.34Å; S297-K301 PolarHBondContact O-N 2.96Å
298T86Confident85.5Confident98 Ų9850.4 Ų50.460%0.60127%0.265SS*.Hα-helixtrans-63.2-49.8178.7-46.50000111.7N296 A300 K301 E302N296-T298 VanDerWaalsContact C-N 3.26Å; N296-T298 PolarHBondContact O-N 2.99Å; T298-A300 VanDerWaalsContact C-N 3.34Å; T298-A300 PolarHBondContact O-N 3.27Å; T298-K301 WeakPolarHBondContact O-CB 3.49Å; T298-K301 PolarHBondContact O-N 2.86Å; T298-E302 WeakPolarHBondContact O-CG 3.35Å; T298-E302 PolarHBondContact O-N 2.98Å; T298-E302 VanDerWaalsContact O-N 3.07Å
299K86.7Confident85.6Confident112 Ų11258.8 Ų58.849%0.48730%0.301SS..Hα-helixtrans-68.2-34.9177.4-70.4-172.7-177.4179.10112.3L291 N296 K301 E302 I303L291-K299 HydrophobicContact CD1-CB 4.03Å; L291-K299 HydrophobicContact CD2-CB 4.36Å; N296-K299 PolarHBondContact O-N 3.39Å; K299-K301 VanDerWaalsContact C-N 3.32Å; K299-E302 PolarHBondContact O-N 3.06Å; K299-I303 WeakPolarHBondContact O-CG1 3.46Å; K299-I303 PolarHBondContact O-N 3.07Å; K299-I303 VanDerWaalsContact O-N 3.14Å
300A85.8Confident85.8Confident0 Ų059.5 Ų59.50%031%0.307CS..Hα-helixtrans-60.8-44.2174.500000111L291 L292 N296 S297 T298 I303 I304L291-A300 HydrophobicContact CB-CB 3.88Å; L292-A300 HydrophobicContact CD2-CB 3.91Å; L292-A300 HydrophobicContact CG-CB 3.82Å; N296-A300 PolarHBondContact O-N 3.24Å; S297-A300 PolarHBondContact O-N 2.84Å; T298-A300 VanDerWaalsContact C-N 3.34Å; T298-A300 PolarHBondContact O-N 3.27Å; A300-I303 PolarHBondContact O-N 2.74Å; A300-I304 VanDerWaalsContact O-CG1 3.28Å; A300-I304 WeakPolarHBondContact O-CG1 3.5Å; A300-I304 PolarHBondContact O-N 2.85Å
301K86.3Confident86Confident58 Ų5859.3 Ų59.325%0.25231%0.308SS..Hα-helixtrans-59.4-49.9176.1-172.6176.5-177.3-178.60111.7S297 T298 K299 I303 I304 E305 I319 E320S297-K301 WeakPolarHBondContact O-CB 3.34Å; S297-K301 PolarHBondContact O-N 2.96Å; T298-K301 WeakPolarHBondContact O-CB 3.49Å; T298-K301 PolarHBondContact O-N 2.86Å; K299-K301 VanDerWaalsContact C-N 3.32Å; K301-I303 VanDerWaalsContact C-N 3.28Å; K301-I303 PolarHBondContact O-N 3.48Å; K301-I304 PolarHBondContact O-N 3.38Å; K301-E305 WeakPolarHBondContact CE-OE1 3.25Å; K301-E305 HydrophobicContact CG-CG 4.36Å; K301-E305 WeakPolarHBondContact CG-OE1 3.46Å; K301-E305 WeakPolarHBondContact O-CB 3.39Å; K301-E305 WeakPolarHBondContact O-CG 3.31Å; K301-E305 PolarHBondContact O-N 2.76Å; K301-I319 HydrophobicContact CB-CD1 4.48Å; K301-I319 HydrophobicContact CB-CG2 3.81Å; K301-I319 HydrophobicContact CD-CB 4.45Å; K301-I319 HydrophobicContact CD-CG2 4.49Å; K301-I319 HydrophobicContact CG-CB 4.18Å; K301-I319 HydrophobicContact CG-CD1 3.86Å; K301-I319 HydrophobicContact CG-CG2 3.99Å; K301-E320 IonicContact NZ-OE1 3.55Å; K301-E320 PolarHBondContact NZ-OE1 3.44Å
302E89.9Confident86.1Confident118 Ų11867.8 Ų67.855%0.55134%0.344SS*.Hα-helixtrans-55.1-42.9177.5-72.4172.6-175.800112.3T298 K299 A306T298-E302 WeakPolarHBondContact O-CG 3.35Å; T298-E302 PolarHBondContact O-N 2.98Å; T298-E302 VanDerWaalsContact O-N 3.07Å; K299-E302 PolarHBondContact O-N 3.06Å; E302-A306 WeakPolarHBondContact O-CB 3.35Å; E302-A306 PolarHBondContact O-N 3.13Å
303I89.8Confident86.3Confident32 Ų3272.6 Ų72.616%0.16437%0.365CS..Hα-helixtrans-70.2-44.4179.8-65.1171.7000111.2P285 P288 L291 K299 A300 K301 A306 I307P285-I303 HydrophobicContact CB-CD1 4.29Å; P285-I303 HydrophobicContact CB-CG1 4.47Å; P285-I303 HydrophobicContact CB-CG2 3.83Å; P285-I303 HydrophobicContact CG-CG2 4.39Å; P288-I303 HydrophobicContact CG-CB 4.43Å; P288-I303 HydrophobicContact CG-CG2 3.8Å; L291-I303 HydrophobicContact CD1-CD1 3.51Å; K299-I303 WeakPolarHBondContact O-CG1 3.46Å; K299-I303 PolarHBondContact O-N 3.07Å; K299-I303 VanDerWaalsContact O-N 3.14Å; A300-I303 PolarHBondContact O-N 2.74Å; K301-I303 VanDerWaalsContact C-N 3.28Å; K301-I303 PolarHBondContact O-N 3.48Å; I303-A306 PolarHBondContact O-N 3.3Å; I303-I307 HydrophobicContact CG2-CD1 3.95Å; I303-I307 HydrophobicContact CG2-CG1 4.5Å; I303-I307 VanDerWaalsContact O-CG1 3.3Å; I303-I307 WeakPolarHBondContact O-CG1 3.47Å; I303-I307 PolarHBondContact O-N 3.32Å
304I87.9Confident86.3Confident3 Ų374.8 Ų74.82%0.01538%0.376CS..Hα-helixtrans-64.1-42.3179.2-66.7167000110.6F4 I7 A11 P288 A300 K301 A306 I307 A308 L315 I319F4-I304 HydrophobicContact CE2-CD1 4Å; I7-I304 HydrophobicContact CG2-CG2 3.99Å; A11-I304 HydrophobicContact CB-CG2 4.44Å; P288-I304 HydrophobicContact CB-CD1 4.14Å; P288-I304 HydrophobicContact CB-CG1 3.95Å; P288-I304 HydrophobicContact CG-CG1 4.27Å; A300-I304 VanDerWaalsContact O-CG1 3.28Å; A300-I304 WeakPolarHBondContact O-CG1 3.5Å; A300-I304 PolarHBondContact O-N 2.85Å; K301-I304 PolarHBondContact O-N 3.38Å; I304-A306 VanDerWaalsContact C-N 3.35Å; I304-A306 PolarHBondContact O-N 2.71Å; I304-I307 PolarHBondContact O-N 3.18Å; I304-A308 WeakPolarHBondContact O-CB 3.2Å; I304-A308 PolarHBondContact O-N 2.93Å; I304-L315 HydrophobicContact CG2-CD1 3.96Å; I304-L315 HydrophobicContact CG2-CD2 4.23Å; I304-I319 HydrophobicContact CB-CD1 4.27Å; I304-I319 HydrophobicContact CG2-CD1 3.99Å
305E88.1Confident86.1Confident91 Ų9172.7 Ų72.743%0.42537%0.367SS..Hα-helixtrans-62.9-40.4175-73.7177.3-179.600111.7K301 A308 K309 L315K301-E305 WeakPolarHBondContact CE-OE1 3.25Å; K301-E305 HydrophobicContact CG-CG 4.36Å; K301-E305 WeakPolarHBondContact CG-OE1 3.46Å; K301-E305 WeakPolarHBondContact O-CB 3.39Å; K301-E305 WeakPolarHBondContact O-CG 3.31Å; K301-E305 PolarHBondContact O-N 2.76Å; E305-A308 PolarHBondContact O-N 2.88Å; E305-K309 VanDerWaalsContact O-CB 3.25Å; E305-K309 WeakPolarHBondContact O-CB 3.27Å; E305-K309 PolarHBondContact O-N 3.21Å; E305-L315 HydrophobicContact CG-CD1 3.95Å
306A88.8Confident85.3Confident57 Ų5773.3 Ų73.347%0.47136%0.36SS..Hα-helixtrans-62.6-42.1174.100000112.2E302 I303 I304 K309 E310E302-A306 WeakPolarHBondContact O-CB 3.35Å; E302-A306 PolarHBondContact O-N 3.13Å; I303-A306 PolarHBondContact O-N 3.3Å; I304-A306 VanDerWaalsContact C-N 3.35Å; I304-A306 PolarHBondContact O-N 2.71Å; A306-K309 PolarHBondContact O-N 2.71Å; A306-E310 PolarHBondContact O-N 3.02Å
307I89.1Confident84.5Confident4 Ų473.7 Ų73.72%0.02136%0.359CS..Hα-helixtrans-62.4-48.6175.3-68.5166.5000110.3A11 L229 I303 I304 K309 E310 N311A11-I307 HydrophobicContact CB-CG2 4.36Å; L229-I307 HydrophobicContact CD2-CD1 4.33Å; I303-I307 HydrophobicContact CG2-CD1 3.95Å; I303-I307 HydrophobicContact CG2-CG1 4.5Å; I303-I307 VanDerWaalsContact O-CG1 3.3Å; I303-I307 WeakPolarHBondContact O-CG1 3.47Å; I303-I307 PolarHBondContact O-N 3.32Å; I304-I307 PolarHBondContact O-N 3.18Å; I307-K309 PolarHBondContact O-N 3.18Å; I307-E310 PolarHBondContact O-N 3.23Å; I307-N311 VanDerWaalsContact O-CB 3.31Å; I307-N311 WeakPolarHBondContact O-CB 3.42Å; I307-N311 VanDerWaalsContact O-CG 3.28Å; I307-N311 PolarHBondContact O-N 2.89Å
308A87.6Confident83.7Confident3 Ų376.7 Ų76.73%0.02537%0.372CS..Hα-helixtrans-62.2-42.1179.800000111.8A11 I304 E305 N311 K312 K313 L315A11-A308 HydrophobicContact CB-CB 4.29Å; I304-A308 WeakPolarHBondContact O-CB 3.2Å; I304-A308 PolarHBondContact O-N 2.93Å; E305-A308 PolarHBondContact O-N 2.88Å; A308-N311 CarbonylContact O-C 3.27Å; A308-N311 PolarHBondContact O-N 2.95Å; A308-K312 PolarHBondContact O-N 2.88Å; A308-K313 PolarHBondContact O-N 3.43Å; A308-L315 HydrophobicContact CB-CD1 3.78Å; A308-L315 HydrophobicContact CB-CD2 4.03Å; A308-L315 HydrophobicContact CB-CG 3.75Å
309K88.9Confident82.7Confident177 Ų17772.4 Ų72.477%0.7735%0.345SS*.Hα-helixtrans-60.9-45.8176.4-174.5177.7-178.1178.20112E305 A306 I307 N311 K312E305-K309 VanDerWaalsContact O-CB 3.25Å; E305-K309 WeakPolarHBondContact O-CB 3.27Å; E305-K309 PolarHBondContact O-N 3.21Å; A306-K309 PolarHBondContact O-N 2.71Å; I307-K309 PolarHBondContact O-N 3.18Å; K309-N311 VanDerWaalsContact C-N 3.32Å; K309-K312 PolarHBondContact O-N 3.46Å
310E88.4Confident81.3Confident62 Ų6273.8 Ų73.829%0.2935%0.353SS..Hα-helixtrans-68.9-32.8177.7-175.3166.2-172.300112.3C17 R20 A306 I307 K312C17-E310 HydrophobicContact CB-CB 4.05Å; C17-E310 HydrophobicContact CB-CG 3.92Å; C17-E310 WeakPolarHBondContact CB-OE2 3.5Å; C17-E310 PolarHBondContact SG-OE2 3.06Å; R20-E310 IonicContact CZ-OE1 2.73Å; R20-E310 IonicContact CZ-OE2 3.2Å; R20-E310 IonicContact NH1-OE1 2.78Å; R20-E310 PolarHBondContact NH1-OE1 3.15Å; R20-E310 IonicContact NH1-OE2 2.68Å; R20-E310 IonicContact NH2-OE1 3.23Å; R20-E310 PolarHBondContact NH2-OE1 2.95Å; R20-E310 IonicContact NH2-OE2 3.26Å; R20-E310 PolarHBondContact NH2-OE2 3.26Å; A306-E310 PolarHBondContact O-N 3.02Å; I307-E310 PolarHBondContact O-N 3.23Å; E310-K312 VanDerWaalsContact C-N 3.26Å; E310-K312 PolarHBondContact O-N 2.9Å
311N88.9Confident80.1Confident23 Ų2378.5 Ų78.512%0.12338%0.382CS..THydrogen-bonded Turntrans-79.9-3.7174.5-71.1-14.6000113.8A11 G15 R16 C17 I307 A308 K309 K313A11-N311 WeakPolarHBondContact O-CB 3.05Å; A11-N311 PolarHBondContact O-ND2 2.77Å; G15-N311 VanDerWaalsContact C-OD1 3.32Å; G15-N311 WeakPolarHBondContact CA-OD1 3.38Å; R16-N311 PolarHBondContact N-OD1 3.26Å; C17-N311 PolarHBondContact N-OD1 3.18Å; I307-N311 VanDerWaalsContact O-CB 3.31Å; I307-N311 WeakPolarHBondContact O-CB 3.42Å; I307-N311 VanDerWaalsContact O-CG 3.28Å; I307-N311 PolarHBondContact O-N 2.89Å; A308-N311 CarbonylContact O-C 3.27Å; A308-N311 PolarHBondContact O-N 2.95Å; K309-N311 VanDerWaalsContact C-N 3.32Å; N311-K313 VanDerWaalsContact C-N 3.28Å; N311-K313 HydrophobicContact CB-CG 4.29Å; N311-K313 PolarHBondContact O-N 2.78Å
312K87.5Confident78.8Confident188 Ų18876.2 Ų76.282%0.81737%0.372SS*.THydrogen-bonded Turntrans55.939.8-174.9-53.9-179.1179.6-177.50112.9A308 K309 E310A308-K312 PolarHBondContact O-N 2.88Å; K309-K312 PolarHBondContact O-N 3.46Å; E310-K312 VanDerWaalsContact C-N 3.26Å; E310-K312 PolarHBondContact O-N 2.9Å
313K85.3Confident77.3Confident113 Ų11380.9 Ų80.949%0.49139%0.385SS..  trans-112.1147.1177.2-69.7-71.2-175170.80110.4E10 A308 N311E10-K313 WeakPolarHBondContact O-CB 3.32Å; A308-K313 PolarHBondContact O-N 3.43Å; N311-K313 VanDerWaalsContact C-N 3.28Å; N311-K313 HydrophobicContact CB-CG 4.29Å; N311-K313 PolarHBondContact O-N 2.78Å
314T79.3Confident75.6Confident93 Ų9381.8 Ų81.857%0.57139%0.39SS*.  trans-99.5135.717446.90000109.4Y316T314-Y316 WeakPolarHBondContact O-CE2 3.25Å; T314-Y316 PolarHBondContact O-OH 2.93Å; T314-Y316 WeakPolarHBondContact OG1-CE1 3.48Å
315L76.9Confident73.9Confident48 Ų4885.6 Ų85.625%0.25141%0.411SS..  trans-92.2127.6176.6-62.2165.3000108.5I7 E10 A11 I304 E305 A308 I319I7-L315 HydrophobicContact CG2-CD2 4.46Å; E10-L315 HydrophobicContact CB-CD2 4.3Å; A11-L315 HydrophobicContact CB-CD2 4.04Å; I304-L315 HydrophobicContact CG2-CD1 3.96Å; I304-L315 HydrophobicContact CG2-CD2 4.23Å; E305-L315 HydrophobicContact CG-CD1 3.95Å; A308-L315 HydrophobicContact CB-CD1 3.78Å; A308-L315 HydrophobicContact CB-CD2 4.03Å; A308-L315 HydrophobicContact CB-CG 3.75Å; L315-I319 HydrophobicContact CD1-CD1 4.1Å
316Y63.8Low72.1Confident160 Ų16085.7 Ų85.763%0.62741%0.414SS*.  trans-105.5-30.2-178.2-25.5-86.8000111.2E10 T314E10-Y316 HydrophobicContact CB-CE2 4.36Å; E10-Y316 VanDerWaalsContact CD-CD2 3.45Å; E10-Y316 HydrophobicContact CG-CD2 4Å; E10-Y316 HydrophobicContact CG-CE2 3.98Å; E10-Y316 WeakPolarHBondContact OE2-CD2 2.97Å; E10-Y316 PolarHBondContact OE2-N 3.13Å; T314-Y316 WeakPolarHBondContact O-CE2 3.25Å; T314-Y316 PolarHBondContact O-OH 2.93Å; T314-Y316 WeakPolarHBondContact OG1-CE1 3.48Å
317K68.1Low70Confident63 Ų6387.1 Ų87.127%0.27443%0.426SS..SBendtrans-80.3138.2178.8-73.8173-1791740112.2T2 E6 I7 E10 I319T2-K317 HydrophobicContact CG2-CB 4.4Å; T2-K317 HydrophobicContact CG2-CD 3.49Å; T2-K317 VanDerWaalsContact CG2-CD 3.49Å; T2-K317 HydrophobicContact CG2-CG 3.91Å; E6-K317 IonicContact OE2-NZ 2.69Å; E6-K317 PolarHBondContact OE2-NZ 3.45Å; I7-K317 HydrophobicContact CD1-CB 4.2Å; I7-K317 HydrophobicContact CG1-CB 4.05Å; I7-K317 HydrophobicContact CG1-CD 4.16Å; E10-K317 WeakPolarHBondContact OE1-CD 3.23Å; E10-K317 WeakPolarHBondContact OE1-CE 3.47Å; E10-K317 WeakPolarHBondContact OE1-CG 3.23Å; E10-K317 IonicContact OE1-NZ 3.6Å; E10-K317 PolarHBondContact OE2-N 3.26Å; K317-I319 PolarHBondContact O-N 3.07Å
318N65.1Low67.7Low108 Ų10895.9 Ų95.958%0.57847%0.467SS*.  trans-71.6115.8176-107.5-23.1000110.6E320 T321N318-E320 PolarHBondContact O-N 3.01Å; N318-T321 PolarHBondContact O-N 2.85Å; N318-T321 PolarHBondContact O-OG1 3.2Å; N318-T321 VanDerWaalsContact O-OG1 3.07Å
319I64.6Low65.8Low7 Ų799 Ų994%0.03649%0.485CS..G310 helixtrans-66.3-22.5178-65.5171.1000111.2I7 K301 I304 L315 K317 T321 L322I7-I319 HydrophobicContact CD1-CG1 4.42Å; I7-I319 HydrophobicContact CG2-CG1 4.45Å; K301-I319 HydrophobicContact CB-CD1 4.48Å; K301-I319 HydrophobicContact CB-CG2 3.81Å; K301-I319 HydrophobicContact CD-CB 4.45Å; K301-I319 HydrophobicContact CD-CG2 4.49Å; K301-I319 HydrophobicContact CG-CB 4.18Å; K301-I319 HydrophobicContact CG-CD1 3.86Å; K301-I319 HydrophobicContact CG-CG2 3.99Å; I304-I319 HydrophobicContact CB-CD1 4.27Å; I304-I319 HydrophobicContact CG2-CD1 3.99Å; L315-I319 HydrophobicContact CD1-CD1 4.1Å; K317-I319 PolarHBondContact O-N 3.07Å; I319-T321 VanDerWaalsContact C-N 3.31Å; I319-T321 PolarHBondContact O-N 3.02Å; I319-L322 HydrophobicContact CB-CD1 4.14Å; I319-L322 HydrophobicContact CG1-CD1 4.42Å; I319-L322 HydrophobicContact CG2-CD1 3.71Å; I319-L322 VanDerWaalsContact O-CB 3.26Å; I319-L322 WeakPolarHBondContact O-CB 3.47Å; I319-L322 WeakPolarHBondContact O-CD1 3.42Å; I319-L322 WeakPolarHBondContact O-CG 3.27Å; I319-L322 PolarHBondContact O-N 2.93Å
320E57.9Low64.1Low141 Ų14194.4 Ų94.466%0.65948%0.475SS*.G310 helixtrans-70.6-20.1-177-74.5165.6-153.600114.4K301 N318 L322K301-E320 IonicContact NZ-OE1 3.55Å; K301-E320 PolarHBondContact NZ-OE1 3.44Å; N318-E320 PolarHBondContact O-N 3.01Å; E320-L322 VanDerWaalsContact C-N 3.31Å
321T60.6Low62.9Low99 Ų9998 Ų9861%0.60750%0.502SS*.G310 helixtrans-881.5174.251.70000113.4N318 I319 R323N318-T321 PolarHBondContact O-N 2.85Å; N318-T321 PolarHBondContact O-OG1 3.2Å; N318-T321 VanDerWaalsContact O-OG1 3.07Å; I319-T321 VanDerWaalsContact C-N 3.31Å; I319-T321 PolarHBondContact O-N 3.02Å; T321-R323 PolarHBondContact O-N 3.38Å
322L59.1Low61.9Low10 Ų1098.7 Ų98.75%0.05251%0.511CS..  trans-75.5113.8177.8-66.5167.4000110.5T2 I7 L292 I319 E320T2-L322 WeakPolarHBondContact O-CD2 3.16Å; I7-L322 HydrophobicContact CD1-CD1 3.43Å; I7-L322 VanDerWaalsContact CD1-CD1 3.43Å; I7-L322 HydrophobicContact CD1-CD2 3.52Å; I7-L322 HydrophobicContact CD1-CG 3.7Å; L292-L322 HydrophobicContact CD1-CB 4.49Å; L292-L322 HydrophobicContact CD1-CD1 4.23Å; L292-L322 HydrophobicContact CD2-CB 4.23Å; I319-L322 HydrophobicContact CB-CD1 4.14Å; I319-L322 HydrophobicContact CG1-CD1 4.42Å; I319-L322 HydrophobicContact CG2-CD1 3.71Å; I319-L322 VanDerWaalsContact O-CB 3.26Å; I319-L322 WeakPolarHBondContact O-CB 3.47Å; I319-L322 WeakPolarHBondContact O-CD1 3.42Å; I319-L322 WeakPolarHBondContact O-CG 3.27Å; I319-L322 PolarHBondContact O-N 2.93Å; E320-L322 VanDerWaalsContact C-N 3.31Å
323R56.8Low61.7Low217 Ų21792.4 Ų92.482%0.81949%0.491SS*.  trans-110.6147.3156-73.4-175.2172.7-172.4-2.3107.8T321 D325T321-R323 PolarHBondContact O-N 3.38Å; R323-D325 PolarHBondContact O-N 2.75Å; R323-D325 VanDerWaalsContact O-N 3.13Å
324D54.3Low61.5Low51 Ų5193.6 Ų93.627%0.27350%0.496SS..  trans-68.8107.6170.8-166.31.7000107.8S293 N326 A327S293-D324 VanDerWaalsContact CB-OD2 3.32Å; S293-D324 WeakPolarHBondContact CB-OD2 3.34Å; D324-N326 PolarHBondContact O-N 3.28Å; D324-N326 VanDerWaalsContact O-N 3.1Å; D324-N326 WeakPolarHBondContact OD1-CB 3.49Å; D324-N326 PolarHBondContact OD1-N 3.47Å; D324-N326 PolarHBondContact OD1-ND2 2.84Å; D324-A327 VanDerWaalsContact O-CB 3.32Å; D324-A327 WeakPolarHBondContact O-CB 3.13Å; D324-A327 PolarHBondContact O-N 3.34Å
325D51.9Low61.7Low83 Ų8394.2 Ų94.244%0.44450%0.496SS..G310 helixtrans-59.7-18.4176-72.5-27000111.2R323 A327R323-D325 PolarHBondContact O-N 2.75Å; R323-D325 VanDerWaalsContact O-N 3.13Å; D325-A327 VanDerWaalsContact C-N 3.29Å; D325-A327 PolarHBondContact O-N 3.11Å
326N50.8Low62Low93 Ų9393.2 Ų93.250%0.49749%0.49SS..G310 helixtrans-75-10.9173.8-58.2-56.9000114.1D324 Q328 T329D324-N326 PolarHBondContact O-N 3.28Å; D324-N326 VanDerWaalsContact O-N 3.1Å; D324-N326 WeakPolarHBondContact OD1-CB 3.49Å; D324-N326 PolarHBondContact OD1-N 3.47Å; D324-N326 PolarHBondContact OD1-ND2 2.84Å; N326-Q328 PolarHBondContact O-N 2.79Å; N326-Q328 VanDerWaalsContact O-N 3.16Å; N326-T329 PolarHBondContact O-N 3.17Å; N326-T329 PolarHBondContact O-OG1 3.21Å
327A45Very low62.9Low87 Ų8785.8 Ų85.872%0.71946%0.461SS*.G310 helixtrans-66.2-15.9176.500000112.7D324 D325D324-A327 VanDerWaalsContact O-CB 3.32Å; D324-A327 WeakPolarHBondContact O-CB 3.13Å; D324-A327 PolarHBondContact O-N 3.34Å; D325-A327 VanDerWaalsContact C-N 3.29Å; D325-A327 PolarHBondContact O-N 3.11Å
328Q40.1Very low64Low187 Ų18785.3 Ų85.387%0.87446%0.464SS*.G310 helixtrans-105.50.8177.7-74.1-177.3-4.100114.4N326 S330N326-Q328 PolarHBondContact O-N 2.79Å; N326-Q328 VanDerWaalsContact O-N 3.16Å; Q328-S330 PolarHBondContact O-N 3.41Å
329T49.3Very low65Low69 Ų6988.3 Ų88.342%0.42347%0.467SS..SBendtrans-69.4126.7177.244.80000110.8N326 T331 F460N326-T329 PolarHBondContact O-N 3.17Å; N326-T329 PolarHBondContact O-OG1 3.21Å; T329-T331 PolarHBondContact O-N 3.26Å; T329-F460 HydrophobicContact CG2-CB 4.35Å
330S52.3Low66.1Low80 Ų8089.3 Ų89.356%0.55947%0.473SS*.  trans-42.2133.5171.847.30000111.3Q328 A332Q328-S330 PolarHBondContact O-N 3.41Å; S330-A332 PolarHBondContact O-N 2.96Å
331T62.9Low67.6Low137 Ų13786.9 Ų86.984%0.8447%0.47SS*.  trans-57.8110.217747.80000109.6T329 S333T329-T331 PolarHBondContact O-N 3.26Å; T331-S333 PolarHBondContact O-N 3.29Å
332A68.6Low68.9Low39 Ų3984.9 Ų84.932%0.32246%0.455SS..  trans-60131.1177.800000110.5S330 F460 V461 L464S330-A332 PolarHBondContact O-N 2.96Å; A332-F460 HydrophobicContact CB-CD2 4.47Å; A332-F460 WeakPolarHBondContact CB-O 3.43Å; A332-V461 HydrophobicContact CB-CG2 4.31Å; A332-L464 HydrophobicContact CB-CD2 4.02Å
333S81.9Confident70.3Confident56 Ų5684.4 Ų84.439%0.39245%0.453SS..  trans-105.9148.2176.6-176.90000110.9T331 L335 D336T331-S333 PolarHBondContact O-N 3.29Å; S333-L335 PolarHBondContact O-N 2.97Å; S333-L335 VanDerWaalsContact O-N 3.15Å; S333-L335 PolarHBondContact OG-N 2.92Å; S333-D336 WeakPolarHBondContact CB-OD2 3.44Å; S333-D336 PolarHBondContact N-OD2 3.38Å; S333-D336 WeakPolarHBondContact O-CB 3.27Å; S333-D336 PolarHBondContact O-N 3.28Å
334F81.7Confident72.1Confident138 Ų13879.7 Ų79.761%0.60544%0.435SS*.Hα-helixtrans-55.8-29.6169.8-70.5-82.2000112D336 L337 L464 V468F334-D336 PolarHBondContact O-N 3.11Å; F334-L337 PolarHBondContact O-N 3.49Å; F334-L464 HydrophobicContact CD1-CD1 4.19Å; F334-L464 HydrophobicContact CE1-CD1 3.74Å; F334-L464 HydrophobicContact CE2-CD1 4.4Å; F334-L464 HydrophobicContact CZ-CD1 3.86Å; F334-V468 HydrophobicContact CD1-CG2 3.68Å; F334-V468 HydrophobicContact CE1-CG2 3.46Å; F334-V468 VanDerWaalsContact CE1-CG2 3.46Å
335L83.9Confident73.9Confident106 Ų10681.5 Ų81.556%0.55544%0.441SS*.Hα-helixtrans-63.8-32.1178-169.464.7000111.7S333 L337 V338 R339S333-L335 PolarHBondContact O-N 2.97Å; S333-L335 VanDerWaalsContact O-N 3.15Å; S333-L335 PolarHBondContact OG-N 2.92Å; L335-L337 PolarHBondContact O-N 3.23Å; L335-V338 HydrophobicContact CD1-CG2 4.17Å; L335-V338 WeakPolarHBondContact O-CG2 3.06Å; L335-V338 PolarHBondContact O-N 3.06Å; L335-V338 VanDerWaalsContact O-N 3.12Å; L335-R339 VanDerWaalsContact O-CB 3.22Å; L335-R339 WeakPolarHBondContact O-CB 3.32Å; L335-R339 PolarHBondContact O-N 3.25Å
336D82.8Confident75.8Confident26 Ų2678.3 Ų78.314%0.13942%0.423CS..Hα-helixtrans-66.7-23.1-177.3-61.8-36.9000112.7S333 F334 V461 I525S333-D336 WeakPolarHBondContact CB-OD2 3.44Å; S333-D336 PolarHBondContact N-OD2 3.38Å; S333-D336 WeakPolarHBondContact O-CB 3.27Å; S333-D336 PolarHBondContact O-N 3.28Å; F334-D336 PolarHBondContact O-N 3.11Å; D336-V461 HydrophobicContact CB-CG2 4.41Å; D336-I525 HydrophobicContact CB-CD1 4.01Å
337L83.3Confident77.8Confident4 Ų474 Ų742%0.02140%0.4CS..Hα-helixtrans-72.2-31.2174.5-77123.7000113.7F334 L335 M343 R344 T347 Y457 V461 L464F334-L337 PolarHBondContact O-N 3.49Å; L335-L337 PolarHBondContact O-N 3.23Å; L337-M343 CarbonylContact O-C 3.54Å; L337-R344 PolarHBondContact O-N 3.07Å; L337-T347 HydrophobicContact CB-CG2 4.48Å; L337-T347 HydrophobicContact CD2-CG2 4.11Å; L337-T347 PolarHBondContact O-OG1 2.97Å; L337-Y457 HydrophobicContact CD2-CD1 4.24Å; L337-Y457 HydrophobicContact CD2-CE1 3.39Å; L337-Y457 HydrophobicContact CG-CE1 4.42Å; L337-V461 HydrophobicContact CD1-CG1 3.98Å; L337-V461 HydrophobicContact CD2-CG1 4.49Å; L337-V461 HydrophobicContact CG-CG1 3.92Å; L337-L464 HydrophobicContact CD1-CD2 3.71Å; L337-L464 HydrophobicContact CD1-CG 3.86Å
338V90.3Very high80.2Confident53 Ų5375.3 Ų75.332%0.32139%0.39SS..Hα-helixtrans-111-9.6-172.8-65.30000112.9L335 R344L335-V338 HydrophobicContact CD1-CG2 4.17Å; L335-V338 WeakPolarHBondContact O-CG2 3.06Å; L335-V338 PolarHBondContact O-N 3.06Å; L335-V338 VanDerWaalsContact O-N 3.12Å; V338-R344 VanDerWaalsContact O-CZ 3.26Å; V338-R344 PolarHBondContact O-NE 3.27Å; V338-R344 PolarHBondContact O-NH2 3.03Å
339R87Confident82.9Confident171 Ų17167 Ų6765%0.64535%0.351SS*.Hα-helixtrans-63.9-50.1-173.5-174.9173-175.6175.4-0.1112.5L335L335-R339 VanDerWaalsContact O-CB 3.22Å; L335-R339 WeakPolarHBondContact O-CB 3.32Å; L335-R339 PolarHBondContact O-N 3.25Å
340T88.3Confident85.1Confident28 Ų2863.7 Ų63.717%0.17233%0.331CS..SBendtrans-100.5149.9-173.664.10000111.7M343 R344 I525 E529T340-M343 VanDerWaalsContact OG1-CB 3.22Å; T340-M343 WeakPolarHBondContact OG1-CB 3.48Å; T340-M343 WeakPolarHBondContact OG1-CG 3.34Å; T340-R344 VanDerWaalsContact O-CB 3.23Å; T340-R344 WeakPolarHBondContact O-CB 3.49Å; T340-R344 PolarHBondContact O-N 3.33Å; T340-I525 HydrophobicContact CG2-CG2 3.86Å; T340-E529 WeakPolarHBondContact CB-OE1 3.3Å; T340-E529 HydrophobicContact CG2-CG 4.21Å; T340-E529 PolarHBondContact OG1-OE1 3.31Å
341P88.6Confident87.1Confident91 Ų9161.8 Ų61.859%0.59131%0.314SS*.Hα-helixtrans-68.7-41.8-165.825.6-33.6000113.5K345 E529P341-K345 WeakPolarHBondContact O-CB 3.44Å; P341-K345 PolarHBondContact O-N 3.3Å; P341-E529 WeakPolarHBondContact CD-OE2 3.34Å; P341-E529 WeakPolarHBondContact CG-OE2 3.4Å
342N88.6Confident88.7Confident56 Ų5658.3 Ų58.330%0.29929%0.287SS..Hα-helixtrans-69.1-45.5177-70.1-28.3000110.1R344 K345 H346 I528 E529N342-R344 VanDerWaalsContact C-N 3.31Å; N342-R344 PolarHBondContact O-N 3.3Å; N342-K345 WeakPolarHBondContact O-CB 3.31Å; N342-K345 PolarHBondContact O-N 3.5Å; N342-K345 VanDerWaalsContact O-N 3.13Å; N342-H346 VanDerWaalsContact C-ND1 3.34Å; N342-H346 PolarHBondContact O-N 3.4Å; N342-H346 PolarHBondContact O-ND1 3.23Å; N342-I528 HydrophobicContact CB-CG2 4.32Å; N342-I528 PolarHBondContact ND2-O 3.17Å; N342-E529 WeakPolarHBondContact CA-OE1 3.37Å; N342-E529 WeakPolarHBondContact CB-OE1 3.22Å; N342-E529 WeakPolarHBondContact CB-OE2 2.96Å; N342-E529 PolarHBondContact N-OE1 2.91Å; N342-E529 PolarHBondContact N-OE2 3.39Å; N342-E529 PolarHBondContact ND2-O 3.3Å; N342-E529 PolarHBondContact ND2-OE2 2.87Å
343M88.8Confident90Very high1 Ų156.4 Ų56.41%0.00527%0.272CS..Hα-helixtrans-55.3-45.1175.2-73.1-64.9-69.100113L337 T340 K345 H346 T347 Y457 P458 I525 I528 E529L337-M343 CarbonylContact O-C 3.54Å; T340-M343 VanDerWaalsContact OG1-CB 3.22Å; T340-M343 WeakPolarHBondContact OG1-CB 3.48Å; T340-M343 WeakPolarHBondContact OG1-CG 3.34Å; M343-K345 VanDerWaalsContact C-N 3.35Å; M343-K345 PolarHBondContact O-N 3.45Å; M343-H346 PolarHBondContact O-N 2.93Å; M343-T347 WeakPolarHBondContact O-CB 3.27Å; M343-T347 PolarHBondContact O-N 2.83Å; M343-T347 PolarHBondContact O-OG1 3.43Å; M343-Y457 HydrophobicContact CE-CD1 3.61Å; M343-Y457 HydrophobicContact CE-CE1 3.72Å; M343-P458 HydrophobicContact CE-CG 4.44Å; M343-I525 HydrophobicContact CG-CG2 3.97Å; M343-I528 HydrophobicContact CE-CD1 4.39Å; M343-I528 HydrophobicContact CG-CG2 4.28Å; M343-I528 HydrophobicContact SD-CB 4.07Å; M343-I528 HydrophobicContact SD-CD1 3.3Å; M343-I528 WeakPolarHBondContact SD-CD1 3.07Å; M343-I528 HydrophobicContact SD-CG1 4.26Å; M343-I528 HydrophobicContact SD-CG2 3.76Å; M343-E529 PolarHBondContact N-OE1 3.47Å
344R92.9Very high90.7Very high118 Ų11854.8 Ų54.845%0.44526%0.257SS..Hα-helixtrans-60.4-45.1176.6-176.6-173-58.3175.85.2111.4L337 V338 T340 N342 T347 F348L337-R344 PolarHBondContact O-N 3.07Å; V338-R344 VanDerWaalsContact O-CZ 3.26Å; V338-R344 PolarHBondContact O-NE 3.27Å; V338-R344 PolarHBondContact O-NH2 3.03Å; T340-R344 VanDerWaalsContact O-CB 3.23Å; T340-R344 WeakPolarHBondContact O-CB 3.49Å; T340-R344 PolarHBondContact O-N 3.33Å; N342-R344 VanDerWaalsContact C-N 3.31Å; N342-R344 PolarHBondContact O-N 3.3Å; R344-T347 PolarHBondContact O-N 3.05Å; R344-F348 HydrophobicContact CG-CD2 3.65Å; R344-F348 HydrophobicContact CG-CE2 3.34Å; R344-F348 HydrophobicContact CG-CZ 4.35Å; R344-F348 VanDerWaalsContact O-CD2 3.31Å; R344-F348 WeakPolarHBondContact O-CD2 3.48Å; R344-F348 PolarHBondContact O-N 2.79Å
345K93.3Very high91.4Very high88 Ų8850.8 Ų50.838%0.38324%0.239SC..Hα-helixtrans-61.1-49.9177.6179.5-174.5168.8-163.40111.4P341 N342 M343 T347 F348 I349 L512P341-K345 WeakPolarHBondContact O-CB 3.44Å; P341-K345 PolarHBondContact O-N 3.3Å; N342-K345 WeakPolarHBondContact O-CB 3.31Å; N342-K345 PolarHBondContact O-N 3.5Å; N342-K345 VanDerWaalsContact O-N 3.13Å; M343-K345 VanDerWaalsContact C-N 3.35Å; M343-K345 PolarHBondContact O-N 3.45Å; K345-T347 VanDerWaalsContact C-N 3.32Å; K345-T347 PolarHBondContact O-N 2.84Å; K345-F348 PolarHBondContact O-N 3.25Å; K345-I349 HydrophobicContact CG-CD1 3.81Å; K345-I349 WeakPolarHBondContact O-CD1 3.15Å; K345-I349 VanDerWaalsContact O-CG1 3.26Å; K345-I349 WeakPolarHBondContact O-CG1 3.47Å; K345-I349 PolarHBondContact O-N 3.15Å; K345-I349 VanDerWaalsContact O-N 3.14Å; K345-L512 WeakPolarHBondContact CE-O 3.44Å; K345-L512 PolarHBondContact NZ-O 3.37Å
346H92.6Very high92Very high16 Ų1645.7 Ų45.77%0.07421%0.213CC..Hα-helixtrans-58.3-46.3177.2-62.1115000110.9N342 M343 I349 L350 L513 P514N342-H346 VanDerWaalsContact C-ND1 3.34Å; N342-H346 PolarHBondContact O-N 3.4Å; N342-H346 PolarHBondContact O-ND1 3.23Å; M343-H346 PolarHBondContact O-N 2.93Å; H346-I349 PolarHBondContact O-N 3.29Å; H346-L350 WeakPolarHBondContact O-CB 3.47Å; H346-L350 VanDerWaalsContact O-CG 3.27Å; H346-L350 WeakPolarHBondContact O-CG 3.47Å; H346-L350 PolarHBondContact O-N 3.07Å; H346-L513 HydrophobicContact CB-CD2 4.47Å; H346-P514 WeakPolarHBondContact NE2-CD 3.42Å; H346-P514 WeakPolarHBondContact NE2-CG 3.06Å
347T92.7Very high92.6Very high3 Ų344.5 Ų44.52%0.01821%0.206CC..Hα-helixtrans-60.5-49.8-179-56.40000112.3L337 M343 R344 K345 I349 L350 M351 Y457L337-T347 HydrophobicContact CB-CG2 4.48Å; L337-T347 HydrophobicContact CD2-CG2 4.11Å; L337-T347 PolarHBondContact O-OG1 2.97Å; M343-T347 WeakPolarHBondContact O-CB 3.27Å; M343-T347 PolarHBondContact O-N 2.83Å; M343-T347 PolarHBondContact O-OG1 3.43Å; R344-T347 PolarHBondContact O-N 3.05Å; K345-T347 VanDerWaalsContact C-N 3.32Å; K345-T347 PolarHBondContact O-N 2.84Å; T347-I349 PolarHBondContact O-N 3.37Å; T347-L350 PolarHBondContact O-N 3.34Å; T347-M351 HydrophobicContact CG2-CG 4.27Å; T347-M351 HydrophobicContact CG2-SD 3.81Å; T347-M351 WeakPolarHBondContact O-CB 3.14Å; T347-M351 WeakPolarHBondContact O-CG 3.47Å; T347-M351 PolarHBondContact O-N 3.42Å; T347-Y457 WeakPolarHBondContact CA-OH 3.38Å; T347-Y457 WeakPolarHBondContact CB-OH 3.45Å; T347-Y457 WeakPolarHBondContact CG2-OH 3.27Å; T347-Y457 PolarHBondContact OG1-OH 2.98Å
348F95Very high93.1Very high115 Ų11544.3 Ų44.350%0.50421%0.205SC..Hα-helixtrans-66-37.8179.9-73.9-49.1000113.4R344 K345 M351 F352R344-F348 HydrophobicContact CG-CD2 3.65Å; R344-F348 HydrophobicContact CG-CE2 3.34Å; R344-F348 HydrophobicContact CG-CZ 4.35Å; R344-F348 VanDerWaalsContact O-CD2 3.31Å; R344-F348 WeakPolarHBondContact O-CD2 3.48Å; R344-F348 PolarHBondContact O-N 2.79Å; K345-F348 PolarHBondContact O-N 3.25Å; F348-M351 HydrophobicContact CD1-SD 4.13Å; F348-F352 WeakPolarHBondContact O-CB 3.42Å; F348-F352 PolarHBondContact O-N 2.94Å
349I96.1Very high93.4Very high11 Ų1141.9 Ų41.96%0.05619%0.191CC..Hα-helixtrans-64.2-44.4176.3-66.4167.4000110.3K345 H346 T347 F352 N353 L509 L512 L513K345-I349 HydrophobicContact CG-CD1 3.81Å; K345-I349 WeakPolarHBondContact O-CD1 3.15Å; K345-I349 VanDerWaalsContact O-CG1 3.26Å; K345-I349 WeakPolarHBondContact O-CG1 3.47Å; K345-I349 PolarHBondContact O-N 3.15Å; K345-I349 VanDerWaalsContact O-N 3.14Å; H346-I349 PolarHBondContact O-N 3.29Å; T347-I349 PolarHBondContact O-N 3.37Å; I349-F352 PolarHBondContact O-N 3.08Å; I349-N353 WeakPolarHBondContact O-CB 3.44Å; I349-N353 PolarHBondContact O-N 3.08Å; I349-N353 PolarHBondContact O-ND2 3.44Å; I349-L509 HydrophobicContact CG1-CB 4.39Å; I349-L509 HydrophobicContact CG2-CB 4.08Å; I349-L512 HydrophobicContact CD1-CB 4.06Å; I349-L513 HydrophobicContact CB-CD2 4.02Å; I349-L513 HydrophobicContact CD1-CD2 3.83Å; I349-L513 HydrophobicContact CD1-CG 4.37Å; I349-L513 HydrophobicContact CG2-CD1 3.88Å; I349-L513 HydrophobicContact CG2-CD2 3.88Å; I349-L513 HydrophobicContact CG2-CG 3.91Å
350L94.8Very high93.8Very high0 Ų033.8 Ų33.80%016%0.16CC..Hα-helixtrans-67-44.1178.6-70.7172.6000111.8H346 T347 F352 N353 W354 V452 N453 L456 Y457 L513H346-L350 WeakPolarHBondContact O-CB 3.47Å; H346-L350 VanDerWaalsContact O-CG 3.27Å; H346-L350 WeakPolarHBondContact O-CG 3.47Å; H346-L350 PolarHBondContact O-N 3.07Å; T347-L350 PolarHBondContact O-N 3.34Å; L350-F352 VanDerWaalsContact C-N 3.32Å; L350-F352 PolarHBondContact O-N 3.24Å; L350-N353 PolarHBondContact O-N 2.69Å; L350-N353 VanDerWaalsContact O-N 3.15Å; L350-W354 VanDerWaalsContact O-CD1 3.26Å; L350-W354 PolarHBondContact O-N 3.38Å; L350-V452 HydrophobicContact CD2-CG1 4.13Å; L350-N453 HydrophobicContact CD1-CB 4.32Å; L350-N453 HydrophobicContact CD2-CB 4.43Å; L350-L456 HydrophobicContact CD1-CD1 3.99Å; L350-L456 HydrophobicContact CD2-CD1 4.35Å; L350-L456 HydrophobicContact CG-CD1 4.43Å; L350-Y457 HydrophobicContact CD1-CE2 3.71Å; L350-L513 HydrophobicContact CD2-CD1 4.41Å
351M95.4Very high94.1Very high41 Ų4132.6 Ų32.620%0.20215%0.152CC..Hα-helixtrans-55.4-46.9174.4-74.7174.178.400111.6T347 F348 N353 W354 F355 V468 C469 L472T347-M351 HydrophobicContact CG2-CG 4.27Å; T347-M351 HydrophobicContact CG2-SD 3.81Å; T347-M351 WeakPolarHBondContact O-CB 3.14Å; T347-M351 WeakPolarHBondContact O-CG 3.47Å; T347-M351 PolarHBondContact O-N 3.42Å; F348-M351 HydrophobicContact CD1-SD 4.13Å; M351-N353 VanDerWaalsContact C-N 3.34Å; M351-N353 PolarHBondContact O-N 3.36Å; M351-W354 PolarHBondContact O-N 2.87Å; M351-F355 WeakPolarHBondContact O-CB 3.45Å; M351-F355 PolarHBondContact O-N 3.12Å; M351-V468 HydrophobicContact SD-CG1 4.49Å; M351-C469 HydrophobicContact CG-CB 4.34Å; M351-L472 HydrophobicContact CB-CG 4.27Å; M351-L472 HydrophobicContact CE-CD2 3.42Å; M351-L472 VanDerWaalsContact CE-CD2 3.42Å; M351-L472 HydrophobicContact CE-CG 3.77Å; M351-L472 HydrophobicContact CG-CG 4.5Å
352F96.6Very high94.4Very high63 Ų6328.4 Ų28.428%0.27613%0.125SC..Hα-helixtrans-65-37.9177.6-176.1-106000112.4F348 I349 L350 T356 I505 A506 L509F348-F352 WeakPolarHBondContact O-CB 3.42Å; F348-F352 PolarHBondContact O-N 2.94Å; I349-F352 PolarHBondContact O-N 3.08Å; L350-F352 VanDerWaalsContact C-N 3.32Å; L350-F352 PolarHBondContact O-N 3.24Å; F352-T356 VanDerWaalsContact O-CB 3.26Å; F352-T356 WeakPolarHBondContact O-CB 3.49Å; F352-T356 PolarHBondContact O-N 3.46Å; F352-T356 PolarHBondContact O-OG1 3Å; F352-I505 HydrophobicContact CE1-CB 4.34Å; F352-I505 HydrophobicContact CE1-CG2 3.86Å; F352-I505 HydrophobicContact CZ-CG2 4.13Å; F352-A506 HydrophobicContact CD1-CB 4.01Å; F352-A506 HydrophobicContact CE1-CB 3.77Å; F352-L509 HydrophobicContact CD1-CD1 3.71Å; F352-L509 HydrophobicContact CE1-CD1 4.08Å; F352-L509 HydrophobicContact CG-CD1 4.43Å
353N96.6Very high94.6Very high0 Ų025.8 Ų25.80%011%0.111CC..Hα-helixtrans-69.7-38.6177.1-88.3-91.2000112.9I349 L350 M351 T356 S357 F406 N410 V449 V510I349-N353 WeakPolarHBondContact O-CB 3.44Å; I349-N353 PolarHBondContact O-N 3.08Å; I349-N353 PolarHBondContact O-ND2 3.44Å; L350-N353 PolarHBondContact O-N 2.69Å; L350-N353 VanDerWaalsContact O-N 3.15Å; M351-N353 VanDerWaalsContact C-N 3.34Å; M351-N353 PolarHBondContact O-N 3.36Å; N353-T356 PolarHBondContact O-N 3.25Å; N353-S357 VanDerWaalsContact O-CB 3.23Å; N353-S357 WeakPolarHBondContact O-CB 3.32Å; N353-S357 PolarHBondContact O-N 3.29Å; N353-S357 PolarHBondContact O-OG 3.5Å; N353-F406 HydrophobicContact CB-CZ 3.85Å; N353-F406 VanDerWaalsContact OD1-CZ 3.27Å; N353-F406 WeakPolarHBondContact OD1-CZ 3.5Å; N353-N410 PolarHBondContact OD1-ND2 3.12Å; N353-V449 HydrophobicContact CB-CG2 3.87Å; N353-V510 WeakPolarHBondContact ND2-CG2 3.22Å; N353-V510 VanDerWaalsContact OD1-CG2 3.25Å; N353-V510 WeakPolarHBondContact OD1-CG2 3.39Å
354W95.6Very high94.8Very high21 Ų2126.5 Ų26.58%0.0812%0.115CC..Hα-helixtrans-61-48.1172.5-88.8101.9000111.6L350 M351 S357 A358 F446 V449 V450 N453 C469 C473L350-W354 VanDerWaalsContact O-CD1 3.26Å; L350-W354 PolarHBondContact O-N 3.38Å; M351-W354 PolarHBondContact O-N 2.87Å; W354-S357 PolarHBondContact O-N 3.01Å; W354-A358 WeakPolarHBondContact O-CB 3.19Å; W354-A358 PolarHBondContact O-N 3.43Å; W354-F446 AromaticContact CE3-CE2 3.81Å; W354-F446 HydrophobicContact CE3-CE2 3.81Å; W354-F446 AromaticContact CZ3-CE2 3.78Å; W354-F446 HydrophobicContact CZ3-CE2 3.78Å; W354-F446 HydrophobicContact CZ3-CZ 4.26Å; W354-V449 HydrophobicContact CB-CG1 4.49Å; W354-V449 HydrophobicContact CD2-CG1 3.3Å; W354-V449 HydrophobicContact CE3-CG1 3.94Å; W354-V449 HydrophobicContact CG-CG1 3.5Å; W354-V449 HydrophobicContact CH2-CG1 4.44Å; W354-V449 HydrophobicContact CZ2-CG1 3.81Å; W354-V449 HydrophobicContact CZ3-CG1 4.48Å; W354-V450 HydrophobicContact CH2-CG2 3.62Å; W354-V450 HydrophobicContact CZ2-CG2 4.01Å; W354-V450 HydrophobicContact CZ3-CG2 4.38Å; W354-N453 PolarHBondContact NE1-ND2 3.22Å; W354-C469 VanDerWaalsContact CB-O 3.27Å; W354-C469 WeakPolarHBondContact CB-O 3.44Å; W354-C469 VanDerWaalsContact CD1-CB 3.43Å; W354-C469 HydrophobicContact CG-CB 4.29Å; W354-C473 HydrophobicContact CB-CB 4.32Å; W354-C473 HydrophobicContact CD2-CB 4.28Å; W354-C473 HydrophobicContact CE3-CB 3.48Å; W354-C473 VanDerWaalsContact CE3-CB 3.48Å; W354-C473 HydrophobicContact CZ3-CB 4.09Å
355F96.1Very high94.7Very high54 Ų5421.2 Ų21.224%0.23710%0.095CC..Hα-helixtrans-59-48.9176.2177.5-100.3000111.9M351 A358 I359 L472 I475M351-F355 WeakPolarHBondContact O-CB 3.45Å; M351-F355 PolarHBondContact O-N 3.12Å; F355-A358 PolarHBondContact O-N 3.37Å; F355-I359 HydrophobicContact CD1-CD1 3.79Å; F355-I359 HydrophobicContact CD2-CD1 4.23Å; F355-I359 HydrophobicContact CE1-CD1 3.24Å; F355-I359 HydrophobicContact CE2-CD1 3.72Å; F355-I359 HydrophobicContact CG-CD1 4.27Å; F355-I359 HydrophobicContact CZ-CD1 3.21Å; F355-I359 HydrophobicContact CZ-CG1 4.47Å; F355-I359 WeakPolarHBondContact O-CG1 3.44Å; F355-I359 PolarHBondContact O-N 3.24Å; F355-L472 WeakPolarHBondContact CA-O 3.17Å; F355-L472 HydrophobicContact CB-CB 4.37Å; F355-I475 HydrophobicContact CD2-CG2 4.5Å; F355-I475 HydrophobicContact CE2-CG2 4.21Å
356T96.7Very high94.6Very high0 Ų017.1 Ų17.10%08%0.078CC..Hα-helixtrans-63-45.5179.6-61.70000111.6F352 N353 A358 I359 V360 I502 A503 A506F352-T356 VanDerWaalsContact O-CB 3.26Å; F352-T356 WeakPolarHBondContact O-CB 3.49Å; F352-T356 PolarHBondContact O-N 3.46Å; F352-T356 PolarHBondContact O-OG1 3Å; N353-T356 PolarHBondContact O-N 3.25Å; T356-A358 VanDerWaalsContact C-N 3.31Å; T356-A358 PolarHBondContact O-N 3.04Å; T356-I359 PolarHBondContact O-N 3.16Å; T356-V360 HydrophobicContact CG2-CG2 4.17Å; T356-V360 WeakPolarHBondContact O-CG2 3.38Å; T356-V360 PolarHBondContact O-N 3.45Å; T356-I502 HydrophobicContact CG2-CB 4.23Å; T356-I502 HydrophobicContact CG2-CD1 4.27Å; T356-I502 HydrophobicContact CG2-CG1 3.93Å; T356-A503 HydrophobicContact CG2-CB 4.43Å; T356-A506 HydrophobicContact CG2-CB 3.81Å
357S95.6Very high94.5Very high0 Ų017.4 Ų17.40%08%0.078CC..Hα-helixtrans-62.1-41.6-179.9-57.90000111.2N353 W354 Y361N353-S357 VanDerWaalsContact O-CB 3.23Å; N353-S357 WeakPolarHBondContact O-CB 3.32Å; N353-S357 PolarHBondContact O-N 3.29Å; N353-S357 PolarHBondContact O-OG 3.5Å; W354-S357 PolarHBondContact O-N 3.01Å; S357-Y361 WeakPolarHBondContact O-CA 3.13Å; S357-Y361 WeakPolarHBondContact O-CB 3.49Å; S357-Y361 PolarHBondContact O-N 3.46Å
358A94.6Very high94.3Very high0 Ų018.3 Ų18.30%08%0.083CC..Hα-helixtrans-61.9-48.1175.700000112.5W354 F355 T356 Q362 C473W354-A358 WeakPolarHBondContact O-CB 3.19Å; W354-A358 PolarHBondContact O-N 3.43Å; F355-A358 PolarHBondContact O-N 3.37Å; T356-A358 VanDerWaalsContact C-N 3.31Å; T356-A358 PolarHBondContact O-N 3.04Å; A358-Q362 WeakPolarHBondContact O-CB 3.3Å; A358-Q362 PolarHBondContact O-N 2.92Å; A358-C473 HydrophobicContact CB-CB 4.37Å; A358-C473 WeakPolarHBondContact CB-O 3.47Å; A358-C473 VanDerWaalsContact CB-SG 3.58Å
359I95.4Very high93.7Very high3 Ų313.4 Ų13.42%0.0157%0.065CC..Hα-helixtrans-61.6-50.7-179.4-74.3173.7000111.2F355 T356 G363 G476 V479 A480 L483 F499 I502F355-I359 HydrophobicContact CD1-CD1 3.79Å; F355-I359 HydrophobicContact CD2-CD1 4.23Å; F355-I359 HydrophobicContact CE1-CD1 3.24Å; F355-I359 HydrophobicContact CE2-CD1 3.72Å; F355-I359 HydrophobicContact CG-CD1 4.27Å; F355-I359 HydrophobicContact CZ-CD1 3.21Å; F355-I359 HydrophobicContact CZ-CG1 4.47Å; F355-I359 WeakPolarHBondContact O-CG1 3.44Å; F355-I359 PolarHBondContact O-N 3.24Å; T356-I359 PolarHBondContact O-N 3.16Å; I359-G363 VanDerWaalsContact O-CA 3.29Å; I359-G363 WeakPolarHBondContact O-CA 3.44Å; I359-G363 PolarHBondContact O-N 2.95Å; I359-G476 VanDerWaalsContact CG1-O 3.29Å; I359-G476 WeakPolarHBondContact CG1-O 3.33Å; I359-V479 HydrophobicContact CD1-CG1 4.48Å; I359-A480 HydrophobicContact CG1-CB 4.41Å; I359-L483 HydrophobicContact CG2-CD2 3.73Å; I359-F499 HydrophobicContact CG2-CD1 3.76Å; I359-F499 HydrophobicContact CG2-CE1 3.56Å; I359-I502 HydrophobicContact CB-CD1 4.21Å; I359-I502 HydrophobicContact CG2-CD1 3.69Å
360V96.6Very high93Very high0 Ų014.8 Ų14.80%07%0.072CC..Hα-helixtrans-73.5-40.5-174.8-179.10000110.4T356 L364 I442 F499 I502 A503T356-V360 HydrophobicContact CG2-CG2 4.17Å; T356-V360 WeakPolarHBondContact O-CG2 3.38Å; T356-V360 PolarHBondContact O-N 3.45Å; V360-L364 HydrophobicContact CG1-CD1 3.85Å; V360-L364 HydrophobicContact CG1-CG 4.19Å; V360-L364 VanDerWaalsContact O-CB 3.25Å; V360-L364 WeakPolarHBondContact O-CB 3.48Å; V360-L364 WeakPolarHBondContact O-CG 3.33Å; V360-L364 PolarHBondContact O-N 2.92Å; V360-I442 HydrophobicContact CB-CD1 3.72Å; V360-I442 HydrophobicContact CB-CG1 3.81Å; V360-I442 HydrophobicContact CG1-CB 4.14Å; V360-I442 HydrophobicContact CG1-CD1 3.79Å; V360-I442 HydrophobicContact CG1-CG1 3.69Å; V360-F499 HydrophobicContact CG1-CB 4.31Å; V360-F499 HydrophobicContact CG2-CB 3.96Å; V360-F499 HydrophobicContact CG2-CD1 4.43Å; V360-F499 HydrophobicContact CG2-CG 4.33Å; V360-I502 HydrophobicContact CG2-CD1 3.8Å; V360-I502 HydrophobicContact CG2-CG1 3.95Å; V360-A503 HydrophobicContact CG2-CB 4.42Å
361Y94.5Very high92.2Very high4 Ų417.4 Ų17.42%0.0169%0.094CC..Hα-helixtrans-63.6-51.8177.4-178.4-99.2000111.1Y36 F246 S357 I365 E386 R439 I442Y36-Y361 HydrophobicContact CE1-CD1 4.21Å; Y36-Y361 AromaticContact CE1-CE1 3.9Å; Y36-Y361 HydrophobicContact CE1-CE1 3.9Å; F246-Y361 WeakPolarHBondContact CE1-OH 3.44Å; S357-Y361 WeakPolarHBondContact O-CA 3.13Å; S357-Y361 WeakPolarHBondContact O-CB 3.49Å; S357-Y361 PolarHBondContact O-N 3.46Å; Y361-I365 HydrophobicContact CD1-CD1 3.96Å; Y361-I365 HydrophobicContact CE1-CD1 3.56Å; Y361-I365 WeakPolarHBondContact O-CG1 3.31Å; Y361-I365 PolarHBondContact O-N 2.88Å; Y361-E386 PolarHBondContact OH-OE1 3.44Å; Y361-R439 PolarHBondContact O-NH1 3.26Å; Y361-R439 PolarHBondContact OH-NH2 2.87Å; Y361-I442 HydrophobicContact CD2-CG2 4.3Å
362Q93.1Very high90.9Very high3 Ų319.3 Ų19.31%0.01412%0.124CC..Hα-helixtrans-69.2-42.1-179.8-162.4-179.7-50.900111.5Y36 N158 A358 L364 I365 M366 G477 A480Y36-Q362 PolarHBondContact OH-OE1 2.94Å; N158-Q362 PolarHBondContact ND2-NE2 3.43Å; N158-Q362 PolarHBondContact ND2-OE1 2.75Å; A358-Q362 WeakPolarHBondContact O-CB 3.3Å; A358-Q362 PolarHBondContact O-N 2.92Å; Q362-L364 PolarHBondContact O-N 3.29Å; Q362-I365 WeakPolarHBondContact O-CB 3.38Å; Q362-I365 PolarHBondContact O-N 2.86Å; Q362-M366 HydrophobicContact CB-CE 4.38Å; Q362-M366 HydrophobicContact CG-CE 3.83Å; Q362-M366 HydrophobicContact CG-SD 4.27Å; Q362-M366 PolarHBondContact O-N 3.11Å; Q362-G477 PolarHBondContact NE2-O 3.2Å; Q362-G477 VanDerWaalsContact NE2-O 3.1Å; Q362-A480 HydrophobicContact CB-CB 4.11Å; Q362-A480 HydrophobicContact CG-CB 4.49Å
363G93.5Very high90Very high0 Ų017.9 Ų17.90%013%0.127CC..Hα-helixtrans-60.6-42.6179.100000112.9I359 I365 M366 R367I359-G363 VanDerWaalsContact O-CA 3.29Å; I359-G363 WeakPolarHBondContact O-CA 3.44Å; I359-G363 PolarHBondContact O-N 2.95Å; G363-I365 VanDerWaalsContact C-N 3.34Å; G363-I365 PolarHBondContact O-N 2.61Å; G363-M366 PolarHBondContact O-N 2.91Å; G363-R367 WeakPolarHBondContact O-CB 3.3Å; G363-R367 PolarHBondContact O-N 3.02Å
364L92.9Very high89.5Confident17 Ų1721.9 Ų21.99%0.08915%0.149CC..Hα-helixtrans-66.8-32.9175.5-72.8178.6000112.8V360 Q362 I442 L496 F499V360-L364 HydrophobicContact CG1-CD1 3.85Å; V360-L364 HydrophobicContact CG1-CG 4.19Å; V360-L364 VanDerWaalsContact O-CB 3.25Å; V360-L364 WeakPolarHBondContact O-CB 3.48Å; V360-L364 WeakPolarHBondContact O-CG 3.33Å; V360-L364 PolarHBondContact O-N 2.92Å; Q362-L364 PolarHBondContact O-N 3.29Å; L364-I442 HydrophobicContact CD1-CG2 3.98Å; L364-L496 HydrophobicContact CD2-CD2 3.72Å; L364-F499 HydrophobicContact CD2-CD2 4.44Å
365I90.9Very high89.1Confident6 Ų621.4 Ų21.43%0.03115%0.148CC..Hα-helixtrans-65.7-51.8173.8-64.6167.4000110.2Y36 V37 V40 Y361 Q362 G363 R367 V368 F379 R439Y36-I365 HydrophobicContact CE1-CD1 4.45Å; V37-I365 HydrophobicContact CB-CG2 3.97Å; V37-I365 HydrophobicContact CG1-CD1 3.55Å; V37-I365 HydrophobicContact CG1-CG1 4.48Å; V37-I365 HydrophobicContact CG1-CG2 3.78Å; V40-I365 HydrophobicContact CG2-CG2 4.13Å; Y361-I365 HydrophobicContact CD1-CD1 3.96Å; Y361-I365 HydrophobicContact CE1-CD1 3.56Å; Y361-I365 WeakPolarHBondContact O-CG1 3.31Å; Y361-I365 PolarHBondContact O-N 2.88Å; Q362-I365 WeakPolarHBondContact O-CB 3.38Å; Q362-I365 PolarHBondContact O-N 2.86Å; G363-I365 VanDerWaalsContact C-N 3.34Å; G363-I365 PolarHBondContact O-N 2.61Å; I365-R367 PolarHBondContact O-N 3.14Å; I365-V368 WeakPolarHBondContact O-CB 3.49Å; I365-V368 PolarHBondContact O-N 3.06Å; I365-V368 VanDerWaalsContact O-N 3.12Å; I365-F379 HydrophobicContact CG2-CE2 3.72Å; I365-F379 HydrophobicContact CG2-CZ 4.32Å; I365-R439 VanDerWaalsContact CG1-NH1 3.32Å
366M91.3Very high88.8Confident3 Ų320.5 Ų20.52%0.01514%0.143CC..Hα-helixtrans-64.7-30.7-177.5-68.4-180-58.800111.3I39 Q154 Q362 G363 V368 G369 A480 P481 L484 Y485I39-M366 HydrophobicContact CG2-CG 4.42Å; Q154-M366 HydrophobicContact CG-SD 4.16Å; Q362-M366 HydrophobicContact CB-CE 4.38Å; Q362-M366 HydrophobicContact CG-CE 3.83Å; Q362-M366 HydrophobicContact CG-SD 4.27Å; Q362-M366 PolarHBondContact O-N 3.11Å; G363-M366 PolarHBondContact O-N 2.91Å; M366-V368 VanDerWaalsContact C-N 3.25Å; M366-V368 PolarHBondContact O-N 3.22Å; M366-G369 PolarHBondContact O-N 2.92Å; M366-A480 HydrophobicContact CE-CB 4Å; M366-P481 HydrophobicContact CE-CB 4.11Å; M366-P481 HydrophobicContact CE-CG 3.92Å; M366-P481 HydrophobicContact SD-CB 4.01Å; M366-P481 HydrophobicContact SD-CG 3.9Å; M366-L484 VanDerWaalsContact C-CD2 3.49Å; M366-L484 HydrophobicContact CB-CD2 3.28Å; M366-L484 HydrophobicContact CE-CD2 4.4Å; M366-Y485 HydrophobicContact CB-CE2 4.48Å; M366-Y485 HydrophobicContact SD-CE2 4.23Å
367R90.5Very high88.5Confident22 Ų2224.8 Ų24.88%0.08317%0.165CC..Hα-helixtrans-60-34.1174.9-174.1175.4178-126.80.1113G363 I365 G369 I370 A371 L484 E493G363-R367 WeakPolarHBondContact O-CB 3.3Å; G363-R367 PolarHBondContact O-N 3.02Å; I365-R367 PolarHBondContact O-N 3.14Å; R367-G369 PolarHBondContact O-N 3.15Å; R367-I370 HydrophobicContact CG-CG1 4.35Å; R367-I370 VanDerWaalsContact O-CG1 3.24Å; R367-I370 WeakPolarHBondContact O-CG1 3.4Å; R367-I370 PolarHBondContact O-N 3.37Å; R367-A371 PolarHBondContact O-N 3.47Å; R367-A371 VanDerWaalsContact O-N 3.15Å; R367-L484 HydrophobicContact CB-CD1 3.96Å; R367-L484 HydrophobicContact CB-CD2 4.39Å; R367-L484 HydrophobicContact CG-CD1 4.39Å; R367-E493 IonicContact CZ-OE2 2.83Å; R367-E493 IonicContact NH2-OE1 3.71Å; R367-E493 PolarHBondContact NH2-OE1 3.3Å; R367-E493 IonicContact NH2-OE2 3.93Å; R367-E493 PolarHBondContact NH2-OE2 3.12Å
368V87.5Confident88.2Confident21 Ų2125.8 Ų25.813%0.12717%0.171CC..Hα-helixtrans-56.9-33.6175.4175.30000111.1I365 M366 I370 D378 F379I365-V368 WeakPolarHBondContact O-CB 3.49Å; I365-V368 PolarHBondContact O-N 3.06Å; I365-V368 VanDerWaalsContact O-N 3.12Å; M366-V368 VanDerWaalsContact C-N 3.25Å; M366-V368 PolarHBondContact O-N 3.22Å; V368-I370 VanDerWaalsContact C-N 3.29Å; V368-I370 PolarHBondContact O-N 3.47Å; V368-D378 HydrophobicContact CG1-CB 3.59Å; V368-F379 HydrophobicContact CG1-CB 4.19Å; V368-F379 HydrophobicContact CG1-CD2 4.2Å
369G83.2Confident88Confident13 Ų1325.9 Ų25.913%0.13417%0.171CC..Hα-helixtrans-68-23.2178.100000115M366 R367M366-G369 PolarHBondContact O-N 2.92Å; R367-G369 PolarHBondContact O-N 3.15Å
370I81.4Confident87.8Confident39 Ų3929.3 Ų29.320%0.219%0.189CC..Hα-helixtrans-110.3-0.2-177.561.9171.2000113.5R367 V368 G372 L484 Y485 A488 L492R367-I370 HydrophobicContact CG-CG1 4.35Å; R367-I370 VanDerWaalsContact O-CG1 3.24Å; R367-I370 WeakPolarHBondContact O-CG1 3.4Å; R367-I370 PolarHBondContact O-N 3.37Å; V368-I370 VanDerWaalsContact C-N 3.29Å; V368-I370 PolarHBondContact O-N 3.47Å; I370-G372 PolarHBondContact O-N 2.91Å; I370-G372 VanDerWaalsContact O-N 3.11Å; I370-L484 HydrophobicContact CD1-CD1 4.3Å; I370-L484 HydrophobicContact CD1-CG 4.32Å; I370-Y485 HydrophobicContact CG2-CD1 4.11Å; I370-Y485 HydrophobicContact CG2-CE1 3.59Å; I370-A488 HydrophobicContact CD1-CB 3.83Å; I370-L492 HydrophobicContact CD1-CD1 3.95Å; I370-L492 HydrophobicContact CG1-CD1 4.36Å
371A77.9Confident87.5Confident55 Ų5531.3 Ų31.346%0.45520%0.199SC..SBendtrans-731.5-174.100000114.3R367 G373R367-A371 PolarHBondContact O-N 3.47Å; R367-A371 VanDerWaalsContact O-N 3.15Å; A371-G373 PolarHBondContact O-N 3.43Å; A371-G373 VanDerWaalsContact O-N 3.14Å
372G67.7Low87.2Confident81 Ų8131.7 Ų31.784%0.83520%0.202SC*.SBendtrans72.5-1.3172.800000116.1I370I370-G372 PolarHBondContact O-N 2.91Å; I370-G372 VanDerWaalsContact O-N 3.11Å
373G77.6Confident87.1Confident33 Ų3331.5 Ų31.534%0.3420%0.202SC..SBendtrans-88.2-167.5176.100000113.9A371 V375A371-G373 PolarHBondContact O-N 3.43Å; A371-G373 VanDerWaalsContact O-N 3.14Å; G373-V375 PolarHBondContact O-N 2.94Å; G373-V375 VanDerWaalsContact O-N 3.07Å
374N86.9Confident87Confident84 Ų8435.9 Ų35.945%0.44923%0.225SC..  trans-75.499.8170.2-174.9-34.3000109.2Y376 I377 D378N374-Y376 PolarHBondContact O-N 2.8Å; N374-Y376 WeakPolarHBondContact OD1-CB 3.32Å; N374-Y376 WeakPolarHBondContact OD1-CD2 3.43Å; N374-Y376 PolarHBondContact OD1-N 2.84Å; N374-I377 HydrophobicContact CB-CB 4.32Å; N374-I377 HydrophobicContact CB-CD1 4.2Å; N374-I377 HydrophobicContact CB-CG1 4.26Å; N374-I377 PolarHBondContact O-N 3.46Å; N374-I377 PolarHBondContact OD1-N 2.78Å; N374-D378 PolarHBondContact O-N 3.29Å
375V87.7Confident86.9Confident11 Ų1136 Ų367%0.06723%0.226CC..Hα-helixtrans-50.6-36.8-177.6-178.30000112.2V40 F41 G373 F379V40-V375 HydrophobicContact CG1-CG1 3.64Å; F41-V375 HydrophobicContact CD1-CG1 4.44Å; F41-V375 HydrophobicContact CE1-CG1 4.01Å; G373-V375 PolarHBondContact O-N 2.94Å; G373-V375 VanDerWaalsContact O-N 3.07Å; V375-F379 WeakPolarHBondContact O-CB 3.35Å; V375-F379 PolarHBondContact O-N 2.87Å
376Y90.3Very high86.9Confident36 Ų3635.8 Ų35.814%0.14123%0.225CC..Hα-helixtrans-67-43.9179.4-58.5-74.7000112.4F41 T254 A257 Y258 N374 L380F41-Y376 HydrophobicContact CD1-CD1 4.24Å; F41-Y376 AromaticContact CD1-CE1 3.85Å; F41-Y376 HydrophobicContact CD1-CE1 3.85Å; F41-Y376 AromaticContact CE1-CD1 3.61Å; F41-Y376 HydrophobicContact CE1-CD1 3.61Å; F41-Y376 AromaticContact CE1-CE1 3.7Å; F41-Y376 HydrophobicContact CE1-CE1 3.7Å; F41-Y376 HydrophobicContact CZ-CD1 4.45Å; T254-Y376 HydrophobicContact CG2-CD1 4.44Å; T254-Y376 WeakPolarHBondContact CG2-O 3.43Å; A257-Y376 VanDerWaalsContact C-CE1 3.43Å; A257-Y376 HydrophobicContact CB-CE1 4.04Å; A257-Y376 VanDerWaalsContact O-CE1 3.29Å; A257-Y376 WeakPolarHBondContact O-CE1 3.38Å; A257-Y376 PolarHBondContact O-OH 3.27Å; A257-Y376 VanDerWaalsContact O-OH 3.04Å; Y258-Y376 HydrophobicContact CD2-CD1 4.4Å; Y258-Y376 HydrophobicContact CD2-CD2 4.08Å; Y258-Y376 HydrophobicContact CD2-CE2 4.21Å; Y258-Y376 HydrophobicContact CD2-CG 4.17Å; N374-Y376 PolarHBondContact O-N 2.8Å; N374-Y376 WeakPolarHBondContact OD1-CB 3.32Å; N374-Y376 WeakPolarHBondContact OD1-CD2 3.43Å; N374-Y376 PolarHBondContact OD1-N 2.84Å; Y376-L380 VanDerWaalsContact O-CB 3.28Å; Y376-L380 WeakPolarHBondContact O-CB 3.29Å; Y376-L380 PolarHBondContact O-N 2.86Å
377I89.9Confident86.9Confident90 Ų9037.8 Ų37.846%0.46223%0.234SC..Hα-helixtrans-69.6-45.3179.4-62.8179000109.9N374 F379 L380 I381N374-I377 HydrophobicContact CB-CB 4.32Å; N374-I377 HydrophobicContact CB-CD1 4.2Å; N374-I377 HydrophobicContact CB-CG1 4.26Å; N374-I377 PolarHBondContact O-N 3.46Å; N374-I377 PolarHBondContact OD1-N 2.78Å; I377-F379 VanDerWaalsContact C-N 3.29Å; I377-F379 PolarHBondContact O-N 3.43Å; I377-L380 WeakPolarHBondContact O-CB 3.28Å; I377-L380 PolarHBondContact O-N 3.41Å; I377-I381 HydrophobicContact CG2-CD1 3.87Å; I377-I381 HydrophobicContact CG2-CG1 4.42Å; I377-I381 VanDerWaalsContact O-CG1 3.31Å; I377-I381 WeakPolarHBondContact O-CG1 3.18Å; I377-I381 PolarHBondContact O-N 2.99Å
378D88.6Confident87Confident21 Ų2139.7 Ų39.711%0.11225%0.248CC..Hα-helixtrans-63.9-38.4-178.4-65.2-26.2000111.3V368 N374 S382V368-D378 HydrophobicContact CG1-CB 3.59Å; N374-D378 PolarHBondContact O-N 3.29Å; D378-S382 WeakPolarHBondContact O-CB 3.45Å; D378-S382 PolarHBondContact O-N 3.49Å
379F89.8Confident87.1Confident2 Ų238.7 Ų38.71%0.00924%0.242CC..Hα-helixtrans-73.1-35.2176.3-156.6-89.3000112.5V37 V40 F41 I250 L253 T254 I365 V368 V375 I377 S382 G383V37-F379 HydrophobicContact CB-CE2 4.46Å; V37-F379 HydrophobicContact CB-CZ 3.83Å; V37-F379 HydrophobicContact CG2-CE1 4.26Å; V37-F379 HydrophobicContact CG2-CZ 3.63Å; V40-F379 HydrophobicContact CB-CD2 4.42Å; V40-F379 HydrophobicContact CB-CE2 4.01Å; V40-F379 HydrophobicContact CG1-CD2 4.01Å; V40-F379 HydrophobicContact CG1-CE2 4.11Å; V40-F379 HydrophobicContact CG2-CE2 3.96Å; F41-F379 AromaticContact CE2-CD1 3.88Å; F41-F379 HydrophobicContact CE2-CD1 3.88Å; F41-F379 HydrophobicContact CE2-CD2 4.39Å; F41-F379 AromaticContact CE2-CE1 3.75Å; F41-F379 HydrophobicContact CE2-CE1 3.75Å; F41-F379 HydrophobicContact CE2-CE2 4.32Å; F41-F379 HydrophobicContact CE2-CG 4.15Å; F41-F379 AromaticContact CE2-CZ 3.97Å; F41-F379 HydrophobicContact CE2-CZ 3.97Å; F41-F379 HydrophobicContact CZ-CB 4.04Å; F41-F379 AromaticContact CZ-CD1 3.81Å; F41-F379 HydrophobicContact CZ-CD1 3.81Å; F41-F379 HydrophobicContact CZ-CD2 4.29Å; F41-F379 HydrophobicContact CZ-CE1 4.17Å; F41-F379 AromaticContact CZ-CG 3.81Å; F41-F379 HydrophobicContact CZ-CG 3.81Å; I250-F379 HydrophobicContact CB-CE1 4.5Å; I250-F379 HydrophobicContact CG2-CD1 3.83Å; I250-F379 HydrophobicContact CG2-CE1 3.37Å; I250-F379 HydrophobicContact CG2-CZ 4.19Å; L253-F379 HydrophobicContact CD2-CE1 4.04Å; L253-F379 HydrophobicContact CD2-CZ 4.23Å; T254-F379 VanDerWaalsContact OG1-CD1 3.3Å; T254-F379 WeakPolarHBondContact OG1-CD1 3.35Å; I365-F379 HydrophobicContact CG2-CE2 3.72Å; I365-F379 HydrophobicContact CG2-CZ 4.32Å; V368-F379 HydrophobicContact CG1-CB 4.19Å; V368-F379 HydrophobicContact CG1-CD2 4.2Å; V375-F379 WeakPolarHBondContact O-CB 3.35Å; V375-F379 PolarHBondContact O-N 2.87Å; I377-F379 VanDerWaalsContact C-N 3.29Å; I377-F379 PolarHBondContact O-N 3.43Å; F379-S382 WeakPolarHBondContact O-CB 3.29Å; F379-S382 PolarHBondContact O-N 3.4Å; F379-G383 PolarHBondContact O-N 3.02Å
380L92.3Very high87.3Confident74 Ų7438.1 Ų38.139%0.38724%0.237SC..Hα-helixtrans-61.2-46.8171.7-173.374.3000111.2L251 T254 Y376 I377 S382 G383 L384L251-L380 HydrophobicContact CD2-CD1 3.82Å; T254-L380 HydrophobicContact CG2-CB 4.28Å; Y376-L380 VanDerWaalsContact O-CB 3.28Å; Y376-L380 WeakPolarHBondContact O-CB 3.29Å; Y376-L380 PolarHBondContact O-N 2.86Å; I377-L380 WeakPolarHBondContact O-CB 3.28Å; I377-L380 PolarHBondContact O-N 3.41Å; L380-S382 VanDerWaalsContact C-N 3.33Å; L380-S382 PolarHBondContact O-N 3.49Å; L380-G383 PolarHBondContact O-N 3.15Å; L380-L384 HydrophobicContact CG-CD1 4.46Å; L380-L384 WeakPolarHBondContact O-CG 3.18Å; L380-L384 PolarHBondContact O-N 3.32Å
381I90.6Very high87.7Confident42 Ų4242.5 Ų42.522%0.21525%0.254CS..Hα-helixtrans-60.1-46.2175.5-67.6168.7000109.8I377 G383 L384 V385 T432 C436I377-I381 HydrophobicContact CG2-CD1 3.87Å; I377-I381 HydrophobicContact CG2-CG1 4.42Å; I377-I381 VanDerWaalsContact O-CG1 3.31Å; I377-I381 WeakPolarHBondContact O-CG1 3.18Å; I377-I381 PolarHBondContact O-N 2.99Å; I381-G383 VanDerWaalsContact C-N 3.34Å; I381-G383 PolarHBondContact O-N 2.85Å; I381-L384 PolarHBondContact O-N 2.96Å; I381-V385 WeakPolarHBondContact O-CG2 3.33Å; I381-V385 PolarHBondContact O-N 3.45Å; I381-T432 HydrophobicContact CD1-CG2 4.4Å; I381-T432 HydrophobicContact CG2-CG2 4.39Å; I381-C436 WeakPolarHBondContact CG2-SG 3.39Å
382S87.5Confident88.2Confident12 Ų1243.2 Ų43.28%0.08425%0.25CS..Hα-helixtrans-57.9-42.9177.1-173.50000112.6D378 F379 L380 V385 R439D378-S382 WeakPolarHBondContact O-CB 3.45Å; D378-S382 PolarHBondContact O-N 3.49Å; F379-S382 WeakPolarHBondContact O-CB 3.29Å; F379-S382 PolarHBondContact O-N 3.4Å; L380-S382 VanDerWaalsContact C-N 3.33Å; L380-S382 PolarHBondContact O-N 3.49Å; S382-V385 PolarHBondContact O-N 3.39Å; S382-R439 PolarHBondContact OG-NE 3.46Å
383G90.3Very high89.1Confident0 Ų039.4 Ų39.40%021%0.211CC..Hα-helixtrans-67.3-38176.300000113.4F379 L380 I381 V385 E386F379-G383 PolarHBondContact O-N 3.02Å; L380-G383 PolarHBondContact O-N 3.15Å; I381-G383 VanDerWaalsContact C-N 3.34Å; I381-G383 PolarHBondContact O-N 2.85Å; G383-V385 VanDerWaalsContact C-N 3.27Å; G383-V385 PolarHBondContact O-N 3.14Å; G383-E386 PolarHBondContact O-N 3.49Å
384L92.5Very high89.5Confident92 Ų9241 Ų4148%0.48221%0.211SC..Hα-helixtrans-65.2-30.3177.5-74.8172.8000112.7L251 L380 I381 E386 F387 P388L251-L384 HydrophobicContact CD1-CD2 4.19Å; L251-L384 HydrophobicContact CD2-CD2 4.2Å; L251-L384 HydrophobicContact CD2-CG 4.09Å; L380-L384 HydrophobicContact CG-CD1 4.46Å; L380-L384 WeakPolarHBondContact O-CG 3.18Å; L380-L384 PolarHBondContact O-N 3.32Å; I381-L384 PolarHBondContact O-N 2.96Å; L384-E386 PolarHBondContact O-N 2.99Å; L384-F387 PolarHBondContact O-N 2.91Å; L384-P388 WeakPolarHBondContact O-CD 3.47Å
385V91.5Very high89.5Confident19 Ų1942 Ų4212%0.11521%0.212CC..Hα-helixtrans-67.1-21.5178.9170.30000112.9I381 S382 G383 F387 P388 A389 C436 R439 L440I381-V385 WeakPolarHBondContact O-CG2 3.33Å; I381-V385 PolarHBondContact O-N 3.45Å; S382-V385 PolarHBondContact O-N 3.39Å; G383-V385 VanDerWaalsContact C-N 3.27Å; G383-V385 PolarHBondContact O-N 3.14Å; V385-F387 PolarHBondContact O-N 3.4Å; V385-P388 WeakPolarHBondContact O-CD 3.39Å; V385-A389 PolarHBondContact O-N 3.47Å; V385-C436 WeakPolarHBondContact CG1-O 3.47Å; V385-C436 HydrophobicContact CG2-CB 3.78Å; V385-R439 HydrophobicContact CB-CG 4.49Å; V385-R439 HydrophobicContact CG1-CB 4.08Å; V385-R439 HydrophobicContact CG1-CG 4.07Å; V385-L440 HydrophobicContact CG1-CB 3.66Å; V385-L440 HydrophobicContact CG1-CG 4.48Å
386E90.1Very high89.5Confident1 Ų142.3 Ų42.31%0.00521%0.213CC..Hα-helixtrans-69.4-31178.4-59.8-161.5170.200112.9S247 I250 Y361 G383 L384 A389 A390 R439 T443S247-E386 VanDerWaalsContact CB-OE2 3.29Å; S247-E386 WeakPolarHBondContact CB-OE2 3.46Å; S247-E386 WeakPolarHBondContact OG-CB 3.26Å; S247-E386 PolarHBondContact OG-OE2 3.4Å; I250-E386 WeakPolarHBondContact CD1-OE1 3.48Å; Y361-E386 PolarHBondContact OH-OE1 3.44Å; G383-E386 PolarHBondContact O-N 3.49Å; L384-E386 PolarHBondContact O-N 2.99Å; E386-A389 WeakPolarHBondContact O-CB 3.24Å; E386-A389 PolarHBondContact O-N 3.13Å; E386-A390 PolarHBondContact O-N 3.34Å; E386-A390 VanDerWaalsContact O-N 3.11Å; E386-R439 IonicContact OE1-NH2 3.89Å; E386-R439 PolarHBondContact OE1-NH2 3.27Å; E386-T443 HydrophobicContact CB-CG2 4.46Å; E386-T443 HydrophobicContact CG-CG2 4.37Å
387F91.5Very high89.1Confident46 Ų4640.9 Ų40.920%0.20221%0.208CC..Hα-helixtrans-67.5-51-179.9-59.6-93.2000112.4V248 L251 L384 V385 A389 A390 F391V248-F387 HydrophobicContact CG2-CE1 3.79Å; V248-F387 HydrophobicContact CG2-CZ 3.71Å; L251-F387 HydrophobicContact CD1-CE2 3.62Å; L251-F387 HydrophobicContact CD1-CZ 3.85Å; L251-F387 HydrophobicContact CG-CE2 4.25Å; L384-F387 PolarHBondContact O-N 2.91Å; V385-F387 PolarHBondContact O-N 3.4Å; F387-A389 PolarHBondContact O-N 3.04Å; F387-A390 PolarHBondContact O-N 2.91Å; F387-F391 HydrophobicContact CB-CE2 4.39Å; F387-F391 WeakPolarHBondContact O-CD2 3.21Å; F387-F391 PolarHBondContact O-N 2.91Å; F387-F391 VanDerWaalsContact O-N 3.12Å
388P92.1Very high88.7Confident61 Ų6140.5 Ų40.540%0.39621%0.207SC..Hα-helixtrans-54.6-38.3172.4-26.534.1000113.3L384 V385 F391 L392 L440L384-P388 WeakPolarHBondContact O-CD 3.47Å; V385-P388 WeakPolarHBondContact O-CD 3.39Å; P388-F391 PolarHBondContact O-N 3.45Å; P388-L392 WeakPolarHBondContact O-CB 3.43Å; P388-L392 VanDerWaalsContact O-CG 3.24Å; P388-L392 WeakPolarHBondContact O-CG 3.34Å; P388-L392 PolarHBondContact O-N 2.98Å; P388-L440 HydrophobicContact CB-CD1 4.14Å
389A90.2Very high88.5Confident0 Ų047.2 Ų47.20%023%0.231CC..Hα-helixtrans-59-48.517700000111.5V385 E386 F387 F391 L392 I393 L440 T443 M444V385-A389 PolarHBondContact O-N 3.47Å; E386-A389 WeakPolarHBondContact O-CB 3.24Å; E386-A389 PolarHBondContact O-N 3.13Å; F387-A389 PolarHBondContact O-N 3.04Å; A389-F391 PolarHBondContact O-N 2.75Å; A389-L392 PolarHBondContact O-N 3.2Å; A389-I393 WeakPolarHBondContact O-CG1 3.34Å; A389-I393 PolarHBondContact O-N 2.59Å; A389-L440 HydrophobicContact CB-CG 4.15Å; A389-T443 HydrophobicContact CB-CG2 3.84Å; A389-M444 HydrophobicContact CB-CG 3.81Å
390A87.6Confident88.4Confident2 Ų251.2 Ų51.22%0.01725%0.252CS..Hα-helixtrans-60.9-42.6177.800000112.6V240 M244 E386 F387 I393 L394V240-A390 HydrophobicContact CG1-CB 3.95Å; M244-A390 HydrophobicContact CE-CB 4.31Å; M244-A390 HydrophobicContact CG-CB 4.02Å; E386-A390 PolarHBondContact O-N 3.34Å; E386-A390 VanDerWaalsContact O-N 3.11Å; F387-A390 PolarHBondContact O-N 2.91Å; A390-I393 PolarHBondContact O-N 2.72Å; A390-L394 WeakPolarHBondContact O-CG 3.43Å; A390-L394 PolarHBondContact O-N 3.39Å; A390-L394 VanDerWaalsContact O-N 3.13Å
391F88.4Confident88.2Confident130 Ų13047.7 Ų47.757%0.5723%0.233SC*.Hα-helixtrans-64.9-40.6175.9-71.6-66.2000112.5F387 P388 A389 I393 L394 F395F387-F391 HydrophobicContact CB-CE2 4.39Å; F387-F391 WeakPolarHBondContact O-CD2 3.21Å; F387-F391 PolarHBondContact O-N 2.91Å; F387-F391 VanDerWaalsContact O-N 3.12Å; P388-F391 PolarHBondContact O-N 3.45Å; A389-F391 PolarHBondContact O-N 2.75Å; F391-I393 VanDerWaalsContact C-N 3.33Å; F391-I393 PolarHBondContact O-N 3.01Å; F391-L394 PolarHBondContact O-N 3.04Å; F391-F395 WeakPolarHBondContact O-CB 3.2Å; F391-F395 PolarHBondContact O-N 2.96Å
392L89.8Confident88.1Confident71 Ų7146.7 Ų46.737%0.37223%0.227SC..Hα-helixtrans-64.1-38.1176.5-73.9170000111.6P388 A389 F395 T396 L440 M444P388-L392 WeakPolarHBondContact O-CB 3.43Å; P388-L392 VanDerWaalsContact O-CG 3.24Å; P388-L392 WeakPolarHBondContact O-CG 3.34Å; P388-L392 PolarHBondContact O-N 2.98Å; A389-L392 PolarHBondContact O-N 3.2Å; L392-F395 PolarHBondContact O-N 3.2Å; L392-T396 VanDerWaalsContact O-CB 3.29Å; L392-T396 WeakPolarHBondContact O-CB 3.38Å; L392-T396 WeakPolarHBondContact O-CG2 3.18Å; L392-T396 PolarHBondContact O-N 3.05Å; L392-T396 PolarHBondContact O-OG1 3Å; L392-L440 HydrophobicContact CD1-CD1 4.02Å; L392-L440 HydrophobicContact CD1-CD2 3.83Å; L392-L440 HydrophobicContact CD1-CG 4.37Å; L392-M444 HydrophobicContact CB-CE 3.92Å; L392-M444 HydrophobicContact CB-SD 3.78Å; L392-M444 HydrophobicContact CD1-SD 4Å
393I86.8Confident88.3Confident1 Ų150.5 Ų50.51%0.00524%0.239CC..Hα-helixtrans-60.3-52.5173.9-71.9159.6000110.9A389 A390 F391 F395 T396 I397 M444 E447 M448A389-I393 WeakPolarHBondContact O-CG1 3.34Å; A389-I393 PolarHBondContact O-N 2.59Å; A390-I393 PolarHBondContact O-N 2.72Å; F391-I393 VanDerWaalsContact C-N 3.33Å; F391-I393 PolarHBondContact O-N 3.01Å; I393-F395 PolarHBondContact O-N 3.44Å; I393-T396 PolarHBondContact O-N 3.36Å; I393-T396 PolarHBondContact O-OG1 3Å; I393-I397 VanDerWaalsContact O-CB 3.32Å; I393-I397 WeakPolarHBondContact O-CB 3.29Å; I393-I397 WeakPolarHBondContact O-CG2 3.26Å; I393-I397 PolarHBondContact O-N 3.06Å; I393-M444 HydrophobicContact CD1-CB 4.33Å; I393-M444 HydrophobicContact CD1-CG 4.17Å; I393-M444 HydrophobicContact CG1-CB 4.25Å; I393-M444 HydrophobicContact CG1-CE 4.21Å; I393-M444 HydrophobicContact CG1-CG 3.98Å; I393-E447 HydrophobicContact CD1-CB 3.64Å; I393-E447 HydrophobicContact CD1-CG 4.11Å; I393-E447 WeakPolarHBondContact CD1-OE2 3.48Å; I393-M448 HydrophobicContact CB-CE 4.17Å; I393-M448 HydrophobicContact CG1-CE 4.08Å; I393-M448 HydrophobicContact CG2-CE 3.78Å; I393-M448 HydrophobicContact CG2-SD 4.4Å
394L85.1Confident88.5Confident65 Ų6554.7 Ų54.734%0.3426%0.261SS..Hα-helixtrans-58.1-37.7179.8-69.2174.5000111.8V240 M244 A390 F391V240-L394 HydrophobicContact CB-CD2 4.36Å; V240-L394 HydrophobicContact CG1-CD1 4.36Å; V240-L394 HydrophobicContact CG1-CD2 4.4Å; V240-L394 HydrophobicContact CG1-CG 4.27Å; V240-L394 HydrophobicContact CG2-CD2 4.04Å; M244-L394 HydrophobicContact CE-CD1 4.25Å; A390-L394 WeakPolarHBondContact O-CG 3.43Å; A390-L394 PolarHBondContact O-N 3.39Å; A390-L394 VanDerWaalsContact O-N 3.13Å; F391-L394 PolarHBondContact O-N 3.04Å
395F86.4Confident88.5Confident106 Ų10650.6 Ų50.647%0.46524%0.24SC..Hα-helixtrans-73.9-40.6178.6-176.3-94.2000113.5F391 L392 I393 R399F391-F395 WeakPolarHBondContact O-CB 3.2Å; F391-F395 PolarHBondContact O-N 2.96Å; L392-F395 PolarHBondContact O-N 3.2Å; I393-F395 PolarHBondContact O-N 3.44Å; F395-R399 VanDerWaalsContact CZ-CZ 3.43Å; F395-R399 WeakPolarHBondContact O-CG 3.31Å
396T87.6Confident88.7Confident17 Ų1749.7 Ų49.710%0.10423%0.234CC..Hα-helixtrans-81.1-35.7-173530000112.9L392 I393 D398 R399 I400L392-T396 VanDerWaalsContact O-CB 3.29Å; L392-T396 WeakPolarHBondContact O-CB 3.38Å; L392-T396 WeakPolarHBondContact O-CG2 3.18Å; L392-T396 PolarHBondContact O-N 3.05Å; L392-T396 PolarHBondContact O-OG1 3Å; I393-T396 PolarHBondContact O-N 3.36Å; I393-T396 PolarHBondContact O-OG1 3Å; T396-D398 VanDerWaalsContact C-N 3.33Å; T396-D398 PolarHBondContact O-N 3.12Å; T396-R399 PolarHBondContact O-N 3.24Å; T396-I400 HydrophobicContact CG2-CD1 3.9Å; T396-I400 PolarHBondContact O-N 2.87Å
397I82.7Confident89Confident7 Ų749.7 Ų49.74%0.03624%0.235CC..Hα-helixtrans-59.6-41.4-172.1-158.8168.2000112.6I393 R402 M448 F451I393-I397 VanDerWaalsContact O-CB 3.32Å; I393-I397 WeakPolarHBondContact O-CB 3.29Å; I393-I397 WeakPolarHBondContact O-CG2 3.26Å; I393-I397 PolarHBondContact O-N 3.06Å; I397-R402 HydrophobicContact CD1-CG 4.42Å; I397-R402 HydrophobicContact CG1-CG 3.98Å; I397-R402 PolarHBondContact O-NH1 3.23Å; I397-M448 HydrophobicContact CB-CE 4.19Å; I397-M448 HydrophobicContact CD1-SD 4.31Å; I397-M448 HydrophobicContact CG1-CE 4.4Å; I397-F451 HydrophobicContact CD1-CD2 4.32Å; I397-F451 HydrophobicContact CD1-CG 4.37Å
398D80.4Confident89.2Confident82 Ų8251 Ų5144%0.43925%0.247SC..Hα-helixtrans-88-21.7-177.3-71.3-23.1000113R236 T396 R517R236-D398 IonicContact CZ-OD1 3.78Å; R236-D398 IonicContact NH1-OD1 3.16Å; R236-D398 PolarHBondContact NH1-OD1 3.34Å; R236-D398 IonicContact NH1-OD2 3.63Å; R236-D398 IonicContact NH2-OD1 3.1Å; T396-D398 VanDerWaalsContact C-N 3.33Å; T396-D398 PolarHBondContact O-N 3.12Å; D398-R517 PolarHBondContact O-NE 3.49Å; D398-R517 VanDerWaalsContact O-NE 3.08Å; D398-R517 PolarHBondContact O-NH2 3Å
399R85.9Confident89.4Confident162 Ų16248.3 Ų48.361%0.61123%0.23SC*.Hα-helixtrans-97.9-38.7-175.9-69.7-172.9-176.7-161.14114.9F395 T396 R517F395-R399 VanDerWaalsContact CZ-CZ 3.43Å; F395-R399 WeakPolarHBondContact O-CG 3.31Å; T396-R399 PolarHBondContact O-N 3.24Å; R399-R517 VanDerWaalsContact O-CZ 3.25Å; R399-R517 PolarHBondContact O-NH1 3.43Å; R399-R517 PolarHBondContact O-NH2 2Å
400I87.4Confident89.7Confident86 Ų8648.3 Ų48.344%0.44123%0.23SC..THydrogen-bonded Turntrans-103.6-38.8-173.5-55.9-179.5000110T396 L404 P405T396-I400 HydrophobicContact CG2-CD1 3.9Å; T396-I400 PolarHBondContact O-N 2.87Å; I400-L404 HydrophobicContact CG2-CB 4.08Å; I400-L404 HydrophobicContact CG2-CD1 4.31Å; I400-P405 HydrophobicContact CB-CG 3.99Å; I400-P405 HydrophobicContact CG2-CG 3.99Å
401G87.2Confident90.2Very high0 Ų051.1 Ų51.10%024%0.244CC..  trans123.1-173.8-168.300000110.7P405 E515G401-P405 WeakPolarHBondContact O-CD 3.45Å; G401-P405 VanDerWaalsContact O-CG 3.27Å; G401-P405 WeakPolarHBondContact O-CG 3.18Å; G401-E515 WeakPolarHBondContact CA-OE1 3.24Å
402R89Confident90.6Very high20 Ų2047.8 Ų47.88%0.07523%0.234CC..SBendtrans-100.8-37.8177.8-70.669.4167.5147.91.6111.3I397 F406 V452 E455 E515 T516I397-R402 HydrophobicContact CD1-CG 4.42Å; I397-R402 HydrophobicContact CG1-CG 3.98Å; I397-R402 PolarHBondContact O-NH1 3.23Å; R402-F406 WeakPolarHBondContact O-CB 3.12Å; R402-F406 PolarHBondContact O-N 3.1Å; R402-F406 VanDerWaalsContact O-N 3.15Å; R402-V452 HydrophobicContact CB-CG2 3.8Å; R402-V452 HydrophobicContact CG-CG2 4.39Å; R402-E455 IonicContact CZ-OE1 3.6Å; R402-E455 IonicContact NE-OE1 2.78Å; R402-E455 PolarHBondContact NE-OE1 2.89Å; R402-E455 IonicContact NE-OE2 3.86Å; R402-E455 PolarHBondContact NE-OE2 3.46Å; R402-E455 IonicContact NH2-OE1 2.86Å; R402-E455 PolarHBondContact NH2-OE1 2.77Å; R402-E515 PolarHBondContact N-OE1 2.94Å; R402-E515 PolarHBondContact N-OE2 2.87Å; R402-T516 WeakPolarHBondContact CD-OG1 3.33Å; R402-T516 WeakPolarHBondContact CG-OG1 3.23Å
403R92.3Very high91Very high93 Ų9344.4 Ų44.435%0.35122%0.216SC..Hα-helixtrans-63.9-51-173179.7-174.2171.6-169.3-6.9112.6A407 L511 L513 E515R403-A407 WeakPolarHBondContact O-CB 3.22Å; R403-A407 PolarHBondContact O-N 2.92Å; R403-L511 PolarHBondContact NE-O 2.83Å; R403-L511 VanDerWaalsContact NE-O 3.12Å; R403-L511 PolarHBondContact NH2-O 3.24Å; R403-L513 WeakPolarHBondContact CD-O 3.34Å; R403-L513 PolarHBondContact NE-O 3.36Å; R403-L513 VanDerWaalsContact NE-O 3.09Å; R403-E515 VanDerWaalsContact CB-OE2 3.3Å; R403-E515 WeakPolarHBondContact CB-OE2 3.11Å; R403-E515 PolarHBondContact N-OE2 3.34Å; R403-E515 VanDerWaalsContact N-OE2 3.16Å
404L93.1Very high91.5Very high88 Ų8844.4 Ų44.446%0.46122%0.216SC..Hα-helixtrans-69.3-48.8-175.7-70.6173.5000112.8I400 F406 A407 T408 L511I400-L404 HydrophobicContact CG2-CB 4.08Å; I400-L404 HydrophobicContact CG2-CD1 4.31Å; L404-F406 PolarHBondContact O-N 3.24Å; L404-A407 PolarHBondContact O-N 2.96Å; L404-T408 WeakPolarHBondContact O-CB 3.45Å; L404-T408 VanDerWaalsContact O-CG2 3.31Å; L404-T408 WeakPolarHBondContact O-CG2 3.44Å; L404-T408 PolarHBondContact O-N 2.92Å; L404-T408 PolarHBondContact O-OG1 3.43Å; L404-L511 HydrophobicContact CD2-CD2 4.34Å
405P93.8Very high92.1Very high5 Ų544.3 Ų44.33%0.03222%0.218CC..Hα-helixtrans-58.4-38.6175.1-28.740000112.4I400 G401 T408 A409 M448I400-P405 HydrophobicContact CB-CG 3.99Å; I400-P405 HydrophobicContact CG2-CG 3.99Å; G401-P405 WeakPolarHBondContact O-CD 3.45Å; G401-P405 VanDerWaalsContact O-CG 3.27Å; G401-P405 WeakPolarHBondContact O-CG 3.18Å; P405-T408 WeakPolarHBondContact CA-OG1 3.22Å; P405-T408 PolarHBondContact O-OG1 3.12Å; P405-A409 WeakPolarHBondContact O-CB 2.97Å; P405-A409 PolarHBondContact O-N 3.03Å; P405-M448 HydrophobicContact CB-CE 4.01Å
406F95Very high92.5Very high0 Ų039.7 Ų39.70%020%0.199CC..Hα-helixtrans-67.9-43.8179.2-178-152.5000113.1N353 R402 L404 N410 A445 M448 V449 V452 V510 L513N353-F406 HydrophobicContact CB-CZ 3.85Å; N353-F406 VanDerWaalsContact OD1-CZ 3.27Å; N353-F406 WeakPolarHBondContact OD1-CZ 3.5Å; R402-F406 WeakPolarHBondContact O-CB 3.12Å; R402-F406 PolarHBondContact O-N 3.1Å; R402-F406 VanDerWaalsContact O-N 3.15Å; L404-F406 PolarHBondContact O-N 3.24Å; F406-N410 WeakPolarHBondContact CE2-ND2 3.38Å; F406-N410 PolarHBondContact O-N 3.18Å; F406-N410 PolarHBondContact O-ND2 3.39Å; F406-A445 HydrophobicContact CD2-CB 4.42Å; F406-A445 HydrophobicContact CE2-CB 4.37Å; F406-A445 WeakPolarHBondContact CE2-O 3.49Å; F406-M448 HydrophobicContact CB-CB 3.97Å; F406-M448 HydrophobicContact CB-CG 4.44Å; F406-M448 HydrophobicContact CD2-CB 3.77Å; F406-M448 HydrophobicContact CG-CB 3.95Å; F406-V449 HydrophobicContact CE1-CG2 4.27Å; F406-V449 HydrophobicContact CE2-CB 4.43Å; F406-V449 HydrophobicContact CE2-CG2 3.38Å; F406-V449 HydrophobicContact CZ-CB 4.29Å; F406-V449 HydrophobicContact CZ-CG2 3.23Å; F406-V452 HydrophobicContact CD1-CB 4.36Å; F406-V452 HydrophobicContact CD1-CG1 4.38Å; F406-V452 HydrophobicContact CD1-CG2 3.98Å; F406-V452 HydrophobicContact CE1-CG1 4.44Å; F406-V510 HydrophobicContact CB-CG1 4.01Å; F406-V510 HydrophobicContact CD1-CB 4.18Å; F406-V510 HydrophobicContact CD1-CG1 3.3Å; F406-V510 HydrophobicContact CD1-CG2 3.69Å; F406-V510 HydrophobicContact CD2-CG2 4.44Å; F406-V510 HydrophobicContact CE1-CB 4.24Å; F406-V510 HydrophobicContact CE1-CG1 3.81Å; F406-V510 HydrophobicContact CE1-CG2 3.3Å; F406-V510 HydrophobicContact CE2-CG2 4.09Å; F406-V510 HydrophobicContact CG-CG1 3.77Å; F406-V510 HydrophobicContact CG-CG2 4.21Å; F406-V510 HydrophobicContact CZ-CG2 3.49Å; F406-V510 VanDerWaalsContact CZ-CG2 3.49Å; F406-L513 HydrophobicContact CE1-CD1 4.41Å
407A96.4Very high92.9Very high1 Ų139 Ų391%0.00820%0.195CC..Hα-helixtrans-66.5-46.4176.300000112R403 L404 N410 I411 G507 V510 L511R403-A407 WeakPolarHBondContact O-CB 3.22Å; R403-A407 PolarHBondContact O-N 2.92Å; L404-A407 PolarHBondContact O-N 2.96Å; A407-N410 PolarHBondContact O-N 3.19Å; A407-I411 WeakPolarHBondContact O-CG1 3.42Å; A407-I411 PolarHBondContact O-N 2.96Å; A407-G507 WeakPolarHBondContact CB-O 3.38Å; A407-V510 HydrophobicContact CB-CB 4.09Å; A407-V510 HydrophobicContact CB-CG1 3.85Å; A407-L511 HydrophobicContact CB-CD2 3.46Å; A407-L511 VanDerWaalsContact CB-CD2 3.46Å; A407-L511 HydrophobicContact CB-CG 3.81Å
408T95.8Very high93.5Very high74 Ų7442 Ų4245%0.45421%0.208SC..Hα-helixtrans-65.3-39.3-179.152.40000112L404 P405 N410 I411 V412L404-T408 WeakPolarHBondContact O-CB 3.45Å; L404-T408 VanDerWaalsContact O-CG2 3.31Å; L404-T408 WeakPolarHBondContact O-CG2 3.44Å; L404-T408 PolarHBondContact O-N 2.92Å; L404-T408 PolarHBondContact O-OG1 3.43Å; P405-T408 WeakPolarHBondContact CA-OG1 3.22Å; P405-T408 PolarHBondContact O-OG1 3.12Å; T408-N410 PolarHBondContact O-N 3.41Å; T408-I411 PolarHBondContact O-N 3.29Å; T408-V412 VanDerWaalsContact O-CB 3.31Å; T408-V412 WeakPolarHBondContact O-CB 3.46Å; T408-V412 WeakPolarHBondContact O-CG2 3.37Å; T408-V412 PolarHBondContact O-N 3.33Å
409A96.3Very high94.2Very high5 Ų541.8 Ų41.84%0.04121%0.206CC..Hα-helixtrans-58.1-46175.700000112.4P405 A413 G441 M444 A445P405-A409 WeakPolarHBondContact O-CB 2.97Å; P405-A409 PolarHBondContact O-N 3.03Å; A409-A413 WeakPolarHBondContact O-CB 3.41Å; A409-A413 PolarHBondContact O-N 3Å; A409-G441 WeakPolarHBondContact CB-O 3.44Å; A409-G441 CarbonylContact O-C 3.34Å; A409-M444 HydrophobicContact CB-CB 3.83Å; A409-A445 HydrophobicContact CB-CB 4.1Å
410N96.8Very high94.6Very high0 Ų034.2 Ų34.20%018%0.177CC..Hα-helixtrans-64.2-44.1175.3-88.8-62.1000113N353 F406 A407 T408 A413 G414N353-N410 PolarHBondContact OD1-ND2 3.12Å; F406-N410 WeakPolarHBondContact CE2-ND2 3.38Å; F406-N410 PolarHBondContact O-N 3.18Å; F406-N410 PolarHBondContact O-ND2 3.39Å; A407-N410 PolarHBondContact O-N 3.19Å; T408-N410 PolarHBondContact O-N 3.41Å; N410-A413 WeakPolarHBondContact O-CB 3.46Å; N410-A413 PolarHBondContact O-N 3.16Å; N410-G414 PolarHBondContact O-N 3.36Å
411I97.6Very high94.8Very high61 Ų6130.7 Ų30.731%0.31316%0.161SC..Hα-helixtrans-65.9-43.8179-67.1167.5000110.5A407 T408 A413 G414 V415A407-I411 WeakPolarHBondContact O-CG1 3.42Å; A407-I411 PolarHBondContact O-N 2.96Å; T408-I411 PolarHBondContact O-N 3.29Å; I411-A413 VanDerWaalsContact C-N 3.33Å; I411-A413 PolarHBondContact O-N 3.3Å; I411-G414 PolarHBondContact O-N 3.37Å; I411-V415 HydrophobicContact CG2-CG2 4.08Å; I411-V415 WeakPolarHBondContact O-CB 3.02Å; I411-V415 VanDerWaalsContact O-CG2 3.3Å; I411-V415 WeakPolarHBondContact O-CG2 3.47Å; I411-V415 PolarHBondContact O-N 3.15Å
412V97.2Very high94.9Very high60 Ų6038.4 Ų38.436%0.36420%0.199SC..Hα-helixtrans-61.5-43.2176.2168.70000110.4T408 G414 S416 I437T408-V412 VanDerWaalsContact O-CB 3.31Å; T408-V412 WeakPolarHBondContact O-CB 3.46Å; T408-V412 WeakPolarHBondContact O-CG2 3.37Å; T408-V412 PolarHBondContact O-N 3.33Å; V412-G414 VanDerWaalsContact C-N 3.34Å; V412-G414 PolarHBondContact O-N 3.36Å; V412-S416 WeakPolarHBondContact O-CB 3.32Å; V412-S416 PolarHBondContact O-N 3.2Å; V412-S416 PolarHBondContact O-OG 3.18Å; V412-I437 HydrophobicContact CG1-CG2 3.6Å
413A97.3Very high95Very high0 Ų038.8 Ų38.80%020%0.203CC..Hα-helixtrans-56.9-49.3173.300000111.3A409 N410 I411 S416 C417 I442A409-A413 WeakPolarHBondContact O-CB 3.41Å; A409-A413 PolarHBondContact O-N 3Å; N410-A413 WeakPolarHBondContact O-CB 3.46Å; N410-A413 PolarHBondContact O-N 3.16Å; I411-A413 VanDerWaalsContact C-N 3.33Å; I411-A413 PolarHBondContact O-N 3.3Å; A413-S416 PolarHBondContact O-N 2.9Å; A413-C417 PolarHBondContact O-N 3.12Å; A413-C417 PolarHBondContact O-SG 3.07Å; A413-I442 HydrophobicContact CB-CB 4.05Å; A413-I442 HydrophobicContact CB-CD1 4.43Å
414G97.3Very high94.7Very high0 Ų038 Ų380%021%0.209CC..Hα-helixtrans-67.4-46.1-176.300000114N410 I411 V412 S416 C417 F418 G500N410-G414 PolarHBondContact O-N 3.36Å; I411-G414 PolarHBondContact O-N 3.37Å; V412-G414 VanDerWaalsContact C-N 3.34Å; V412-G414 PolarHBondContact O-N 3.36Å; G414-S416 VanDerWaalsContact C-N 3.32Å; G414-S416 PolarHBondContact O-N 3.36Å; G414-C417 WeakPolarHBondContact O-CB 3.26Å; G414-C417 PolarHBondContact O-N 3.49Å; G414-F418 VanDerWaalsContact O-CD2 3.28Å; G414-F418 WeakPolarHBondContact O-CD2 3.36Å; G414-F418 PolarHBondContact O-N 2.91Å; G414-F418 VanDerWaalsContact O-N 3.12Å; G414-G500 WeakPolarHBondContact O-CA 3.45Å
415V97.6Very high94Very high64 Ų6439.2 Ų39.239%0.38822%0.217SC..Hα-helixtrans-62.3-40.9176.1172.40000110.8I411 C417 F418 I419I411-V415 HydrophobicContact CG2-CG2 4.08Å; I411-V415 WeakPolarHBondContact O-CB 3.02Å; I411-V415 VanDerWaalsContact O-CG2 3.3Å; I411-V415 WeakPolarHBondContact O-CG2 3.47Å; I411-V415 PolarHBondContact O-N 3.15Å; V415-C417 VanDerWaalsContact C-N 3.34Å; V415-C417 PolarHBondContact O-N 3.1Å; V415-F418 PolarHBondContact O-N 3.4Å; V415-I419 HydrophobicContact CG1-CD1 3.72Å; V415-I419 HydrophobicContact CG1-CG1 4.31Å; V415-I419 VanDerWaalsContact O-CG1 3.31Å; V415-I419 WeakPolarHBondContact O-CG1 3.18Å; V415-I419 PolarHBondContact O-N 3.44Å
416S96.6Very high93.5Very high9 Ų943.5 Ų43.56%0.06325%0.246CC..Hα-helixtrans-64.5-38.1177.1-57.80000112.1V412 A413 G414 I419 T420 V434 I437 G438V412-S416 WeakPolarHBondContact O-CB 3.32Å; V412-S416 PolarHBondContact O-N 3.2Å; V412-S416 PolarHBondContact O-OG 3.18Å; A413-S416 PolarHBondContact O-N 2.9Å; G414-S416 VanDerWaalsContact C-N 3.32Å; G414-S416 PolarHBondContact O-N 3.36Å; S416-I419 PolarHBondContact O-N 2.94Å; S416-T420 VanDerWaalsContact O-CB 3.32Å; S416-T420 WeakPolarHBondContact O-CB 3.46Å; S416-T420 PolarHBondContact O-N 3.2Å; S416-T420 PolarHBondContact O-OG1 2.76Å; S416-V434 WeakPolarHBondContact O-CG1 3.49Å; S416-I437 WeakPolarHBondContact OG-CG2 3.37Å; S416-G438 VanDerWaalsContact CB-CA 3.44Å
417C95.6Very high93Very high3 Ų348.9 Ų48.92%0.0227%0.271CS..Hα-helixtrans-61-44.3172.6-70.80000111.8A413 G414 V415 T420 A421 L496A413-C417 PolarHBondContact O-N 3.12Å; A413-C417 PolarHBondContact O-SG 3.07Å; G414-C417 WeakPolarHBondContact O-CB 3.26Å; G414-C417 PolarHBondContact O-N 3.49Å; V415-C417 VanDerWaalsContact C-N 3.34Å; V415-C417 PolarHBondContact O-N 3.1Å; C417-T420 PolarHBondContact O-N 3.47Å; C417-A421 PolarHBondContact O-N 3.46Å; C417-A421 VanDerWaalsContact O-N 3.08Å; C417-L496 HydrophobicContact CB-CB 4.33Å; C417-L496 HydrophobicContact CB-CD2 4.31Å; C417-L496 WeakPolarHBondContact CB-O 3.46Å; C417-L496 WeakPolarHBondContact O-CD1 3.5Å
418F95.8Very high92.4Very high69 Ų6953.1 Ų53.130%0.30329%0.29SS..Hα-helixtrans-62.3-46.3175.9-70.6-53000112.6G414 V415 T420 A421 M422 I497 G500 A501G414-F418 VanDerWaalsContact O-CD2 3.28Å; G414-F418 WeakPolarHBondContact O-CD2 3.36Å; G414-F418 PolarHBondContact O-N 2.91Å; G414-F418 VanDerWaalsContact O-N 3.12Å; V415-F418 PolarHBondContact O-N 3.4Å; F418-T420 VanDerWaalsContact C-N 3.31Å; F418-T420 PolarHBondContact O-N 3.45Å; F418-A421 WeakPolarHBondContact O-CB 3.37Å; F418-A421 PolarHBondContact O-N 3.42Å; F418-M422 WeakPolarHBondContact O-CG 3.46Å; F418-M422 PolarHBondContact O-N 3.19Å; F418-I497 HydrophobicContact CD1-CG2 4.34Å; F418-I497 HydrophobicContact CE1-CB 4.34Å; F418-I497 HydrophobicContact CE1-CG2 3.83Å; F418-I497 WeakPolarHBondContact CE1-O 3.18Å; F418-G500 VanDerWaalsContact CZ-C 3.43Å; F418-A501 HydrophobicContact CZ-CB 4.02Å
419I95.2Very high91.9Very high78 Ų7858.5 Ų58.540%0.430%0.302SS..Hα-helixtrans-62.4-42.8179-64.8168.2000110.1V415 S416 A421 M422 I423 V434V415-I419 HydrophobicContact CG1-CD1 3.72Å; V415-I419 HydrophobicContact CG1-CG1 4.31Å; V415-I419 VanDerWaalsContact O-CG1 3.31Å; V415-I419 WeakPolarHBondContact O-CG1 3.18Å; V415-I419 PolarHBondContact O-N 3.44Å; S416-I419 PolarHBondContact O-N 2.94Å; I419-A421 VanDerWaalsContact C-N 3.28Å; I419-A421 PolarHBondContact O-N 3.42Å; I419-M422 PolarHBondContact O-N 3.31Å; I419-I423 HydrophobicContact CG2-CD1 3.89Å; I419-I423 HydrophobicContact CG2-CG1 4.45Å; I419-I423 WeakPolarHBondContact O-CG1 3.39Å; I419-I423 PolarHBondContact O-N 2.91Å; I419-V434 HydrophobicContact CB-CG1 3.88Å; I419-V434 HydrophobicContact CG2-CG1 3.78Å; I419-V434 HydrophobicContact CG2-CG2 4.22Å
420T92.7Very high91.6Very high2 Ų262.1 Ų62.11%0.01232%0.323CS..Hα-helixtrans-60.6-37.5178.6-55.50000111.9S416 C417 F418 M422 I423 K431 V434 A435 L496S416-T420 VanDerWaalsContact O-CB 3.32Å; S416-T420 WeakPolarHBondContact O-CB 3.46Å; S416-T420 PolarHBondContact O-N 3.2Å; S416-T420 PolarHBondContact O-OG1 2.76Å; C417-T420 PolarHBondContact O-N 3.47Å; F418-T420 VanDerWaalsContact C-N 3.31Å; F418-T420 PolarHBondContact O-N 3.45Å; T420-M422 PolarHBondContact O-N 3.49Å; T420-I423 PolarHBondContact O-N 3.49Å; T420-K431 HydrophobicContact CG2-CG 3.82Å; T420-V434 WeakPolarHBondContact OG1-CG1 3.44Å; T420-A435 HydrophobicContact CG2-CB 4.25Å; T420-L496 HydrophobicContact CG2-CD1 3.74Å
421A91.6Very high91.3Very high12 Ų1263.4 Ų63.410%0.09933%0.329CS..Hα-helixtrans-67.1-23.7177.200000113.5C417 F418 I419 E493 L496 I497C417-A421 PolarHBondContact O-N 3.46Å; C417-A421 VanDerWaalsContact O-N 3.08Å; F418-A421 WeakPolarHBondContact O-CB 3.37Å; F418-A421 PolarHBondContact O-N 3.42Å; I419-A421 VanDerWaalsContact C-N 3.28Å; I419-A421 PolarHBondContact O-N 3.42Å; A421-E493 HydrophobicContact CB-CB 4.14Å; A421-L496 HydrophobicContact CB-CB 4.19Å; A421-L496 HydrophobicContact CB-CD1 3.97Å; A421-I497 HydrophobicContact CB-CG1 4.02Å
422M90.9Very high90.8Very high163 Ų16361.7 Ų61.780%0.80332%0.321SS*.Hα-helixtrans-91.5-12.9179.7-62.3-169.780.700113.5F418 I419 T420 P424F418-M422 WeakPolarHBondContact O-CG 3.46Å; F418-M422 PolarHBondContact O-N 3.19Å; I419-M422 PolarHBondContact O-N 3.31Å; T420-M422 PolarHBondContact O-N 3.49Å; M422-P424 WeakPolarHBondContact O-CD 3.5Å
423I90.1Very high90.5Very high28 Ų2862.8 Ų62.814%0.14433%0.328CS..SBendtrans-83.6123.6-177.8-68163.7000109.6I419 T420 H427 V430 K431 V434I419-I423 HydrophobicContact CG2-CD1 3.89Å; I419-I423 HydrophobicContact CG2-CG1 4.45Å; I419-I423 WeakPolarHBondContact O-CG1 3.39Å; I419-I423 PolarHBondContact O-N 2.91Å; T420-I423 PolarHBondContact O-N 3.49Å; I423-H427 HydrophobicContact CG2-CB 4.24Å; I423-V430 HydrophobicContact CD1-CG1 4.06Å; I423-K431 HydrophobicContact CB-CB 4.43Å; I423-K431 HydrophobicContact CB-CG 4.39Å; I423-K431 HydrophobicContact CG2-CB 3.82Å; I423-K431 HydrophobicContact CG2-CG 4.25Å; I423-V434 HydrophobicContact CD1-CB 4.29Å; I423-V434 HydrophobicContact CD1-CG2 3.93Å
424P85.6Confident90.4Very high76 Ų7663.9 Ų63.949%0.49433%0.334SS..  trans-66152.8173.9-17.130.1000112.4M422 S426 H427M422-P424 WeakPolarHBondContact O-CD 3.5Å; P424-S426 PolarHBondContact O-N 2.95Å; P424-S426 VanDerWaalsContact O-N 3.08Å; P424-H427 PolarHBondContact O-N 2.78Å; P424-H427 VanDerWaalsContact O-N 3.15Å
425D79.5Confident90.1Very high114 Ų11465.5 Ų65.561%0.6135%0.348SS*.G310 helixtrans-64.9-14.9-179.1-60-41.6000113.9H427 K431D425-H427 PolarHBondContact O-N 3.36Å; D425-K431 IonicContact OD1-NZ 2.77Å; D425-K431 PolarHBondContact OD1-NZ 3.35Å
426S82.1Confident89.9Confident94 Ų9463.8 Ų63.866%0.65734%0.338SS*.G310 helixtrans-61.7-25.4173.560.10000113.4P424P424-S426 PolarHBondContact O-N 2.95Å; P424-S426 VanDerWaalsContact O-N 3.08Å
427H85.7Confident89.8Confident113 Ų11367.1 Ų67.152%0.52336%0.355SS..G310 helixtrans-108.157.6-179.2-65.7-62.1000112.2I423 P424 D425 W429 V430 K431I423-H427 HydrophobicContact CG2-CB 4.24Å; P424-H427 PolarHBondContact O-N 2.78Å; P424-H427 VanDerWaalsContact O-N 3.15Å; D425-H427 PolarHBondContact O-N 3.36Å; H427-W429 PolarHBondContact O-N 2.76Å; H427-V430 HydrophobicContact CB-CB 4.27Å; H427-V430 HydrophobicContact CB-CG2 4.34Å; H427-V430 PolarHBondContact O-N 3.1Å; H427-V430 VanDerWaalsContact O-N 3.1Å; H427-K431 PolarHBondContact O-N 2.64Å
428F82.5Confident89.7Confident90 Ų9067 Ų6740%0.39536%0.355SS..Hα-helixtrans-45.1-55.3-177.7178.6-99.9000113.8V430 K431 T432F428-V430 VanDerWaalsContact C-N 3.31Å; F428-V430 PolarHBondContact O-N 2.88Å; F428-K431 WeakPolarHBondContact O-CB 3.49Å; F428-K431 PolarHBondContact O-N 2.7Å; F428-T432 PolarHBondContact O-N 3.4Å; F428-T432 PolarHBondContact O-OG1 3.11Å; F428-T432 VanDerWaalsContact O-OG1 3.05Å
429W85.9Confident89.6Confident188 Ų18864.2 Ų64.271%0.71234%0.342SS*.Hα-helixtrans-60.9-37.1-176.9-75.1109000113.5H427 V433H427-W429 PolarHBondContact O-N 2.76Å; W429-V433 WeakPolarHBondContact O-CB 3.41Å; W429-V433 VanDerWaalsContact O-CG2 3.24Å; W429-V433 WeakPolarHBondContact O-CG2 3.49Å; W429-V433 PolarHBondContact O-N 3.16Å
430V90.6Very high89.6Confident80 Ų8062.4 Ų62.449%0.48533%0.333SS..Hα-helixtrans-69.5-45.2178.1-176.40000109.8I423 H427 F428 T432 V433 V434I423-V430 HydrophobicContact CD1-CG1 4.06Å; H427-V430 HydrophobicContact CB-CB 4.27Å; H427-V430 HydrophobicContact CB-CG2 4.34Å; H427-V430 PolarHBondContact O-N 3.1Å; H427-V430 VanDerWaalsContact O-N 3.1Å; F428-V430 VanDerWaalsContact C-N 3.31Å; F428-V430 PolarHBondContact O-N 2.88Å; V430-T432 VanDerWaalsContact C-N 3.33Å; V430-T432 PolarHBondContact O-N 3.04Å; V430-V433 PolarHBondContact O-N 3.37Å; V430-V434 WeakPolarHBondContact O-CG2 3.2Å; V430-V434 PolarHBondContact O-N 3.38Å
431K89.2Confident89.7Confident27 Ų2762.4 Ų62.412%0.11733%0.333CS..Hα-helixtrans-57.7-46.2176.1-163.5177.2-173.4-176.50111T420 I423 D425 H427 F428 V434 A435 E493T420-K431 HydrophobicContact CG2-CG 3.82Å; I423-K431 HydrophobicContact CB-CB 4.43Å; I423-K431 HydrophobicContact CB-CG 4.39Å; I423-K431 HydrophobicContact CG2-CB 3.82Å; I423-K431 HydrophobicContact CG2-CG 4.25Å; D425-K431 IonicContact OD1-NZ 2.77Å; D425-K431 PolarHBondContact OD1-NZ 3.35Å; H427-K431 PolarHBondContact O-N 2.64Å; F428-K431 WeakPolarHBondContact O-CB 3.49Å; F428-K431 PolarHBondContact O-N 2.7Å; K431-V434 PolarHBondContact O-N 3.31Å; K431-A435 VanDerWaalsContact O-CB 3.3Å; K431-A435 WeakPolarHBondContact O-CB 3.25Å; K431-A435 PolarHBondContact O-N 3.48Å; K431-E493 WeakPolarHBondContact CE-OE1 3.44Å; K431-E493 IonicContact NZ-OE1 3.84Å; K431-E493 PolarHBondContact NZ-OE1 3.12Å
432T88.3Confident89.9Confident25 Ų2561.9 Ų61.915%0.15333%0.329CS..Hα-helixtrans-64.6-44.2178.9-58.20000112.2I381 F428 V430 V434 A435 C436I381-T432 HydrophobicContact CD1-CG2 4.4Å; I381-T432 HydrophobicContact CG2-CG2 4.39Å; F428-T432 PolarHBondContact O-N 3.4Å; F428-T432 PolarHBondContact O-OG1 3.11Å; F428-T432 VanDerWaalsContact O-OG1 3.05Å; V430-T432 VanDerWaalsContact C-N 3.33Å; V430-T432 PolarHBondContact O-N 3.04Å; T432-V434 PolarHBondContact O-N 3.4Å; T432-A435 PolarHBondContact O-N 3.08Å; T432-C436 WeakPolarHBondContact O-CB 3.26Å; T432-C436 PolarHBondContact O-N 3.37Å; T432-C436 PolarHBondContact O-SG 2.64Å
433V91.2Very high90Very high84 Ų8454.2 Ų54.251%0.50929%0.291SS..Hα-helixtrans-62.1-45.6177.9168.30000111.3W429 V430 C436 I437W429-V433 WeakPolarHBondContact O-CB 3.41Å; W429-V433 VanDerWaalsContact O-CG2 3.24Å; W429-V433 WeakPolarHBondContact O-CG2 3.49Å; W429-V433 PolarHBondContact O-N 3.16Å; V430-V433 PolarHBondContact O-N 3.37Å; V433-C436 WeakPolarHBondContact O-CB 3.26Å; V433-C436 PolarHBondContact O-N 3.38Å; V433-I437 HydrophobicContact CG1-CD1 4.28Å; V433-I437 WeakPolarHBondContact O-CG1 3.48Å; V433-I437 PolarHBondContact O-N 2.83Å
434V93.7Very high90.2Very high22 Ų2253.6 Ų53.613%0.13329%0.288CS..Hα-helixtrans-65.1-41.9177.7179.40000110.9S416 I419 T420 I423 V430 K431 T432 C436 I437 G438S416-V434 WeakPolarHBondContact O-CG1 3.49Å; I419-V434 HydrophobicContact CB-CG1 3.88Å; I419-V434 HydrophobicContact CG2-CG1 3.78Å; I419-V434 HydrophobicContact CG2-CG2 4.22Å; T420-V434 WeakPolarHBondContact OG1-CG1 3.44Å; I423-V434 HydrophobicContact CD1-CB 4.29Å; I423-V434 HydrophobicContact CD1-CG2 3.93Å; V430-V434 WeakPolarHBondContact O-CG2 3.2Å; V430-V434 PolarHBondContact O-N 3.38Å; K431-V434 PolarHBondContact O-N 3.31Å; T432-V434 PolarHBondContact O-N 3.4Å; V434-C436 VanDerWaalsContact C-N 3.28Å; V434-C436 PolarHBondContact O-N 2.95Å; V434-I437 PolarHBondContact O-N 3.36Å; V434-I437 VanDerWaalsContact O-N 3.16Å; V434-G438 PolarHBondContact O-N 3.44Å
435A91.5Very high90.6Very high34 Ų3450 Ų5028%0.28126%0.264SS..Hα-helixtrans-60.4-38.4174.600000112T420 K431 T432 G438 R439T420-A435 HydrophobicContact CG2-CB 4.25Å; K431-A435 VanDerWaalsContact O-CB 3.3Å; K431-A435 WeakPolarHBondContact O-CB 3.25Å; K431-A435 PolarHBondContact O-N 3.48Å; T432-A435 PolarHBondContact O-N 3.08Å; A435-G438 PolarHBondContact O-N 3.15Å; A435-R439 WeakPolarHBondContact O-CB 3.47Å; A435-R439 PolarHBondContact O-N 3.43Å
436C93Very high91.2Very high28 Ų2846.4 Ų46.419%0.18924%0.243CC..Hα-helixtrans-64.7-39.7174.6-69.70000112.3I381 V385 T432 V433 V434 G438 R439 L440I381-C436 WeakPolarHBondContact CG2-SG 3.39Å; V385-C436 WeakPolarHBondContact CG1-O 3.47Å; V385-C436 HydrophobicContact CG2-CB 3.78Å; T432-C436 WeakPolarHBondContact O-CB 3.26Å; T432-C436 PolarHBondContact O-N 3.37Å; T432-C436 PolarHBondContact O-SG 2.64Å; V433-C436 WeakPolarHBondContact O-CB 3.26Å; V433-C436 PolarHBondContact O-N 3.38Å; V434-C436 VanDerWaalsContact C-N 3.28Å; V434-C436 PolarHBondContact O-N 2.95Å; C436-G438 VanDerWaalsContact C-N 3.3Å; C436-G438 PolarHBondContact O-N 3.02Å; C436-R439 WeakPolarHBondContact O-CB 3.41Å; C436-R439 PolarHBondContact O-N 3.05Å; C436-L440 WeakPolarHBondContact O-CB 3.11Å; C436-L440 PolarHBondContact O-N 3.3Å
437I95.2Very high91.5Very high79 Ų7942.8 Ų42.841%0.40522%0.216SC..Hα-helixtrans-62.7-42.3174.1-65.4166.2000110.1V412 S416 V433 V434 L440 G441V412-I437 HydrophobicContact CG1-CG2 3.6Å; S416-I437 WeakPolarHBondContact OG-CG2 3.37Å; V433-I437 HydrophobicContact CG1-CD1 4.28Å; V433-I437 WeakPolarHBondContact O-CG1 3.48Å; V433-I437 PolarHBondContact O-N 2.83Å; V434-I437 PolarHBondContact O-N 3.36Å; V434-I437 VanDerWaalsContact O-N 3.16Å; I437-L440 PolarHBondContact O-N 3.15Å; I437-G441 PolarHBondContact O-N 2.94Å
438G94.5Very high91.7Very high2 Ų237.4 Ų37.42%0.02119%0.191CC..Hα-helixtrans-62.1-43.5175.400000112.7S416 V434 A435 C436 G441 I442S416-G438 VanDerWaalsContact CB-CA 3.44Å; V434-G438 PolarHBondContact O-N 3.44Å; A435-G438 PolarHBondContact O-N 3.15Å; C436-G438 VanDerWaalsContact C-N 3.3Å; C436-G438 PolarHBondContact O-N 3.02Å; G438-G441 PolarHBondContact O-N 2.83Å; G438-I442 PolarHBondContact O-N 2.97Å
439R93.1Very high92.2Very high9 Ų933.1 Ų33.13%0.03417%0.172CC..Hα-helixtrans-60.6-46.8175.9-172.771.8-173.7149.99.4111.9Y361 I365 S382 V385 E386 A435 C436 G441 I442 T443Y361-R439 PolarHBondContact O-NH1 3.26Å; Y361-R439 PolarHBondContact OH-NH2 2.87Å; I365-R439 VanDerWaalsContact CG1-NH1 3.32Å; S382-R439 PolarHBondContact OG-NE 3.46Å; V385-R439 HydrophobicContact CB-CG 4.49Å; V385-R439 HydrophobicContact CG1-CB 4.08Å; V385-R439 HydrophobicContact CG1-CG 4.07Å; E386-R439 IonicContact OE1-NH2 3.89Å; E386-R439 PolarHBondContact OE1-NH2 3.27Å; A435-R439 WeakPolarHBondContact O-CB 3.47Å; A435-R439 PolarHBondContact O-N 3.43Å; C436-R439 WeakPolarHBondContact O-CB 3.41Å; C436-R439 PolarHBondContact O-N 3.05Å; R439-G441 VanDerWaalsContact C-N 3.35Å; R439-G441 PolarHBondContact O-N 2.84Å; R439-I442 VanDerWaalsContact O-CG2 3.32Å; R439-I442 WeakPolarHBondContact O-CG2 3.44Å; R439-I442 PolarHBondContact O-N 3.13Å; R439-T443 PolarHBondContact O-N 2.74Å; R439-T443 PolarHBondContact O-OG1 3.44Å
440L94.6Very high92.2Very high41 Ų4126.1 Ų26.122%0.21515%0.15CC..Hα-helixtrans-58.2-48.6175.5-174.1153000110.7V385 P388 A389 L392 C436 I437 I442 T443 M444V385-L440 HydrophobicContact CG1-CB 3.66Å; V385-L440 HydrophobicContact CG1-CG 4.48Å; P388-L440 HydrophobicContact CB-CD1 4.14Å; A389-L440 HydrophobicContact CB-CG 4.15Å; L392-L440 HydrophobicContact CD1-CD1 4.02Å; L392-L440 HydrophobicContact CD1-CD2 3.83Å; L392-L440 HydrophobicContact CD1-CG 4.37Å; C436-L440 WeakPolarHBondContact O-CB 3.11Å; C436-L440 PolarHBondContact O-N 3.3Å; I437-L440 PolarHBondContact O-N 3.15Å; L440-I442 PolarHBondContact O-N 3.38Å; L440-T443 PolarHBondContact O-N 2.97Å; L440-M444 HydrophobicContact CD2-CG 4.19Å; L440-M444 HydrophobicContact CD2-SD 3.53Å; L440-M444 VanDerWaalsContact CD2-SD 3.53Å; L440-M444 WeakPolarHBondContact O-CG 3.2Å; L440-M444 PolarHBondContact O-N 3.34Å
441G95.7Very high92Very high2 Ų223.3 Ų23.32%0.02113%0.132CC..Hα-helixtrans-58.6-46.1179.200000112.6A409 I437 G438 R439 M444 A445A409-G441 WeakPolarHBondContact CB-O 3.44Å; A409-G441 CarbonylContact O-C 3.34Å; I437-G441 PolarHBondContact O-N 2.94Å; G438-G441 PolarHBondContact O-N 2.83Å; R439-G441 VanDerWaalsContact C-N 3.35Å; R439-G441 PolarHBondContact O-N 2.84Å; G441-M444 PolarHBondContact O-N 2.9Å; G441-A445 WeakPolarHBondContact O-CB 3.36Å; G441-A445 PolarHBondContact O-N 3.17Å
442I95.8Very high92Very high0 Ų022.2 Ų22.20%013%0.127CC..Hα-helixtrans-71.7-36.4-178.7-162.765.7000112.6V360 Y361 L364 A413 G438 R439 L440 M444 A445 F446V360-I442 HydrophobicContact CB-CD1 3.72Å; V360-I442 HydrophobicContact CB-CG1 3.81Å; V360-I442 HydrophobicContact CG1-CB 4.14Å; V360-I442 HydrophobicContact CG1-CD1 3.79Å; V360-I442 HydrophobicContact CG1-CG1 3.69Å; Y361-I442 HydrophobicContact CD2-CG2 4.3Å; L364-I442 HydrophobicContact CD1-CG2 3.98Å; A413-I442 HydrophobicContact CB-CB 4.05Å; A413-I442 HydrophobicContact CB-CD1 4.43Å; G438-I442 PolarHBondContact O-N 2.97Å; R439-I442 VanDerWaalsContact O-CG2 3.32Å; R439-I442 WeakPolarHBondContact O-CG2 3.44Å; R439-I442 PolarHBondContact O-N 3.13Å; L440-I442 PolarHBondContact O-N 3.38Å; I442-M444 VanDerWaalsContact C-N 3.3Å; I442-M444 PolarHBondContact O-N 3.43Å; I442-A445 HydrophobicContact CD1-CB 4.37Å; I442-A445 PolarHBondContact O-N 2.91Å; I442-F446 WeakPolarHBondContact O-CB 3.35Å; I442-F446 PolarHBondContact O-N 3.39Å
443T92.9Very high92.1Very high2 Ų221 Ų211%0.01212%0.12CC..Hα-helixtrans-60.8-44.4173.6-59.40000110.1E386 A389 R439 L440 A445 F446 E447E386-T443 HydrophobicContact CB-CG2 4.46Å; E386-T443 HydrophobicContact CG-CG2 4.37Å; A389-T443 HydrophobicContact CB-CG2 3.84Å; R439-T443 PolarHBondContact O-N 2.74Å; R439-T443 PolarHBondContact O-OG1 3.44Å; L440-T443 PolarHBondContact O-N 2.97Å; T443-A445 PolarHBondContact O-N 2.95Å; T443-F446 PolarHBondContact O-N 3.43Å; T443-E447 PolarHBondContact O-N 3.38Å
444M93.1Very high91.7Very high16 Ų1619.2 Ų19.28%0.07911%0.109CC..Hα-helixtrans-60.5-44.9174.9-73.6-173.662.400112.7A389 L392 I393 A409 L440 G441 I442 M448A389-M444 HydrophobicContact CB-CG 3.81Å; L392-M444 HydrophobicContact CB-CE 3.92Å; L392-M444 HydrophobicContact CB-SD 3.78Å; L392-M444 HydrophobicContact CD1-SD 4Å; I393-M444 HydrophobicContact CD1-CB 4.33Å; I393-M444 HydrophobicContact CD1-CG 4.17Å; I393-M444 HydrophobicContact CG1-CB 4.25Å; I393-M444 HydrophobicContact CG1-CE 4.21Å; I393-M444 HydrophobicContact CG1-CG 3.98Å; A409-M444 HydrophobicContact CB-CB 3.83Å; L440-M444 HydrophobicContact CD2-CG 4.19Å; L440-M444 HydrophobicContact CD2-SD 3.53Å; L440-M444 VanDerWaalsContact CD2-SD 3.53Å; L440-M444 WeakPolarHBondContact O-CG 3.2Å; L440-M444 PolarHBondContact O-N 3.34Å; G441-M444 PolarHBondContact O-N 2.9Å; I442-M444 VanDerWaalsContact C-N 3.3Å; I442-M444 PolarHBondContact O-N 3.43Å; M444-M448 WeakPolarHBondContact O-CB 2.97Å; M444-M448 VanDerWaalsContact O-CG 3.22Å; M444-M448 WeakPolarHBondContact O-CG 3.24Å; M444-M448 PolarHBondContact O-N 3.4Å
445A94.8Very high91.3Very high0 Ų019.5 Ų19.50%011%0.109CC..Hα-helixtrans-62.9-43179.200000111.9F406 A409 G441 I442 T443 M448 V449F406-A445 HydrophobicContact CD2-CB 4.42Å; F406-A445 HydrophobicContact CE2-CB 4.37Å; F406-A445 WeakPolarHBondContact CE2-O 3.49Å; A409-A445 HydrophobicContact CB-CB 4.1Å; G441-A445 WeakPolarHBondContact O-CB 3.36Å; G441-A445 PolarHBondContact O-N 3.17Å; I442-A445 HydrophobicContact CD1-CB 4.37Å; I442-A445 PolarHBondContact O-N 2.91Å; T443-A445 PolarHBondContact O-N 2.95Å; A445-M448 PolarHBondContact O-N 3.3Å; A445-V449 WeakPolarHBondContact O-CG2 3.45Å; A445-V449 PolarHBondContact O-N 3.22Å
446F92Very high91.1Very high39 Ų3918.4 Ų18.417%0.17110%0.098CC..Hα-helixtrans-65.8-40.9-177.4-168.2-137.6000112.5W354 I442 T443 V449 C473W354-F446 AromaticContact CE3-CE2 3.81Å; W354-F446 HydrophobicContact CE3-CE2 3.81Å; W354-F446 AromaticContact CZ3-CE2 3.78Å; W354-F446 HydrophobicContact CZ3-CE2 3.78Å; W354-F446 HydrophobicContact CZ3-CZ 4.26Å; I442-F446 WeakPolarHBondContact O-CB 3.35Å; I442-F446 PolarHBondContact O-N 3.39Å; T443-F446 PolarHBondContact O-N 3.43Å; F446-V449 WeakPolarHBondContact O-CB 3.42Å; F446-C473 VanDerWaalsContact CE2-SG 3.52Å; F446-C473 VanDerWaalsContact CZ-SG 3.56Å
447E89.2Confident90.7Very high17 Ų1717.1 Ų17.18%0.0799%0.089CC..Hα-helixtrans-69.7-40.5174.4-69-175.1-14900112.1Q243 I393 T443 V449 V450 F451Q243-E447 HydrophobicContact CG-CG 4.37Å; Q243-E447 WeakPolarHBondContact CG-OE1 3.29Å; I393-E447 HydrophobicContact CD1-CB 3.64Å; I393-E447 HydrophobicContact CD1-CG 4.11Å; I393-E447 WeakPolarHBondContact CD1-OE2 3.48Å; T443-E447 PolarHBondContact O-N 3.38Å; E447-V449 VanDerWaalsContact C-N 3.3Å; E447-V449 PolarHBondContact O-N 3.14Å; E447-V450 WeakPolarHBondContact O-CB 3.48Å; E447-V450 PolarHBondContact O-N 2.92Å; E447-V450 VanDerWaalsContact O-N 3.16Å; E447-F451 VanDerWaalsContact O-CD2 3.3Å; E447-F451 WeakPolarHBondContact O-CD2 3.18Å; E447-F451 PolarHBondContact O-N 3.01Å
448M89.8Confident90Very high0 Ų013.3 Ų13.30%07%0.07CC..Hα-helixtrans-63.5-35.5177.7-76.3-67-171.900112.7I393 I397 P405 F406 M444 A445 V450 F451 V452I393-M448 HydrophobicContact CB-CE 4.17Å; I393-M448 HydrophobicContact CG1-CE 4.08Å; I393-M448 HydrophobicContact CG2-CE 3.78Å; I393-M448 HydrophobicContact CG2-SD 4.4Å; I397-M448 HydrophobicContact CB-CE 4.19Å; I397-M448 HydrophobicContact CD1-SD 4.31Å; I397-M448 HydrophobicContact CG1-CE 4.4Å; P405-M448 HydrophobicContact CB-CE 4.01Å; F406-M448 HydrophobicContact CB-CB 3.97Å; F406-M448 HydrophobicContact CB-CG 4.44Å; F406-M448 HydrophobicContact CD2-CB 3.77Å; F406-M448 HydrophobicContact CG-CB 3.95Å; M444-M448 WeakPolarHBondContact O-CB 2.97Å; M444-M448 VanDerWaalsContact O-CG 3.22Å; M444-M448 WeakPolarHBondContact O-CG 3.24Å; M444-M448 PolarHBondContact O-N 3.4Å; A445-M448 PolarHBondContact O-N 3.3Å; M448-V450 PolarHBondContact O-N 3.46Å; M448-F451 PolarHBondContact O-N 3.47Å; M448-V452 WeakPolarHBondContact O-CB 3.4Å; M448-V452 WeakPolarHBondContact O-CG2 3.08Å; M448-V452 PolarHBondContact O-N 2.7Å
449V92.4Very high89Confident0 Ų016.2 Ų16.20%09%0.087CC..Hα-helixtrans-52-45.71731590000110.8N353 W354 F406 A445 F446 E447 F451 N453N353-V449 HydrophobicContact CB-CG2 3.87Å; W354-V449 HydrophobicContact CB-CG1 4.49Å; W354-V449 HydrophobicContact CD2-CG1 3.3Å; W354-V449 HydrophobicContact CE3-CG1 3.94Å; W354-V449 HydrophobicContact CG-CG1 3.5Å; W354-V449 HydrophobicContact CH2-CG1 4.44Å; W354-V449 HydrophobicContact CZ2-CG1 3.81Å; W354-V449 HydrophobicContact CZ3-CG1 4.48Å; F406-V449 HydrophobicContact CE1-CG2 4.27Å; F406-V449 HydrophobicContact CE2-CB 4.43Å; F406-V449 HydrophobicContact CE2-CG2 3.38Å; F406-V449 HydrophobicContact CZ-CB 4.29Å; F406-V449 HydrophobicContact CZ-CG2 3.23Å; A445-V449 WeakPolarHBondContact O-CG2 3.45Å; A445-V449 PolarHBondContact O-N 3.22Å; F446-V449 WeakPolarHBondContact O-CB 3.42Å; E447-V449 VanDerWaalsContact C-N 3.3Å; E447-V449 PolarHBondContact O-N 3.14Å; V449-F451 PolarHBondContact O-N 3.17Å; V449-N453 WeakPolarHBondContact O-CB 3.19Å; V449-N453 PolarHBondContact O-N 3.48Å
450V86.7Confident88Confident42 Ų4218.2 Ų18.226%0.25510%0.096SC..Hα-helixtrans-61.2-47.6-178.2-175.70000110.8W354 E447 M448 T454W354-V450 HydrophobicContact CH2-CG2 3.62Å; W354-V450 HydrophobicContact CZ2-CG2 4.01Å; W354-V450 HydrophobicContact CZ3-CG2 4.38Å; E447-V450 WeakPolarHBondContact O-CB 3.48Å; E447-V450 PolarHBondContact O-N 2.92Å; E447-V450 VanDerWaalsContact O-N 3.16Å; M448-V450 PolarHBondContact O-N 3.46Å; V450-T454 WeakPolarHBondContact O-CG2 3.2Å; V450-T454 PolarHBondContact O-N 3.06Å; V450-T454 VanDerWaalsContact O-N 3.17Å; V450-T454 PolarHBondContact O-OG1 3.42Å
451F85.5Confident87.3Confident20 Ų2016.3 Ų16.39%0.0889%0.086CC..Hα-helixtrans-65.9-52.6-179.2-69.3-62.4000112.2R236 V240 I397 E447 M448 V449 N453 T454 E455R236-F451 HydrophobicContact CB-CE1 4.2Å; R236-F451 HydrophobicContact CG-CD1 4.48Å; R236-F451 HydrophobicContact CG-CE1 4.09Å; V240-F451 HydrophobicContact CG2-CE2 4.05Å; V240-F451 HydrophobicContact CG2-CZ 3.81Å; I397-F451 HydrophobicContact CD1-CD2 4.32Å; I397-F451 HydrophobicContact CD1-CG 4.37Å; E447-F451 VanDerWaalsContact O-CD2 3.3Å; E447-F451 WeakPolarHBondContact O-CD2 3.18Å; E447-F451 PolarHBondContact O-N 3.01Å; M448-F451 PolarHBondContact O-N 3.47Å; V449-F451 PolarHBondContact O-N 3.17Å; F451-N453 PolarHBondContact O-N 2.73Å; F451-T454 PolarHBondContact O-N 3.22Å; F451-T454 PolarHBondContact O-OG1 3.14Å; F451-E455 WeakPolarHBondContact O-CG 3.49Å; F451-E455 PolarHBondContact O-N 3.06Å
452V89.3Confident86.6Confident5 Ų518 Ų183%0.039%0.092CC..Hα-helixtrans-60.3-38.7-177.9174.80000110.8L350 R402 F406 M448 E455 L456 L513L350-V452 HydrophobicContact CD2-CG1 4.13Å; R402-V452 HydrophobicContact CB-CG2 3.8Å; R402-V452 HydrophobicContact CG-CG2 4.39Å; F406-V452 HydrophobicContact CD1-CB 4.36Å; F406-V452 HydrophobicContact CD1-CG1 4.38Å; F406-V452 HydrophobicContact CD1-CG2 3.98Å; F406-V452 HydrophobicContact CE1-CG1 4.44Å; M448-V452 WeakPolarHBondContact O-CB 3.4Å; M448-V452 WeakPolarHBondContact O-CG2 3.08Å; M448-V452 PolarHBondContact O-N 2.7Å; V452-E455 PolarHBondContact O-N 3.18Å; V452-L456 HydrophobicContact CG1-CD1 3.49Å; V452-L456 VanDerWaalsContact CG1-CD1 3.49Å; V452-L456 HydrophobicContact CG1-CG 4.11Å; V452-L456 WeakPolarHBondContact O-CB 3.33Å; V452-L456 VanDerWaalsContact O-CG 3.3Å; V452-L456 WeakPolarHBondContact O-CG 3.46Å; V452-L456 PolarHBondContact O-N 3.49Å; V452-L513 HydrophobicContact CG1-CD1 4.29Å
453N89.3Confident85.6Confident0 Ų024.5 Ų24.50%013%0.127CC..Hα-helixtrans-58.5-51.1173.8-171.19.6000111.1L350 W354 V449 F451 E455 L456 Y457 V466L350-N453 HydrophobicContact CD1-CB 4.32Å; L350-N453 HydrophobicContact CD2-CB 4.43Å; W354-N453 PolarHBondContact NE1-ND2 3.22Å; V449-N453 WeakPolarHBondContact O-CB 3.19Å; V449-N453 PolarHBondContact O-N 3.48Å; F451-N453 PolarHBondContact O-N 2.73Å; N453-E455 VanDerWaalsContact C-N 3.31Å; N453-E455 PolarHBondContact O-N 2.6Å; N453-L456 PolarHBondContact O-N 3.18Å; N453-Y457 WeakPolarHBondContact O-CD2 3.36Å; N453-Y457 WeakPolarHBondContact OD1-CD2 3.45Å; N453-Y457 WeakPolarHBondContact OD1-CE2 3.2Å; N453-V466 HydrophobicContact CB-CG2 4.42Å; N453-V466 WeakPolarHBondContact ND2-CA 3.5Å
454T83.6Confident85Confident45 Ų4526.1 Ų26.128%0.27614%0.135SC..Hα-helixtrans-64.8-30.6178.360.20000114.2V450 F451 R462 V466V450-T454 WeakPolarHBondContact O-CG2 3.2Å; V450-T454 PolarHBondContact O-N 3.06Å; V450-T454 VanDerWaalsContact O-N 3.17Å; V450-T454 PolarHBondContact O-OG1 3.42Å; F451-T454 PolarHBondContact O-N 3.22Å; F451-T454 PolarHBondContact O-OG1 3.14Å; T454-R462 WeakPolarHBondContact O-CD 3.4Å; T454-R462 PolarHBondContact O-NE 2.86Å; T454-V466 HydrophobicContact CG2-CG2 3.79Å
455E85.9Confident84.6Confident28 Ų2825.4 Ų25.413%0.13113%0.132CC..Hα-helixtrans-82.1-27.4-177.2-69.5-179.2175.600113.1R402 F451 V452 N453 T516 L521 P522R402-E455 IonicContact CZ-OE1 3.6Å; R402-E455 IonicContact NE-OE1 2.78Å; R402-E455 PolarHBondContact NE-OE1 2.89Å; R402-E455 IonicContact NE-OE2 3.86Å; R402-E455 PolarHBondContact NE-OE2 3.46Å; R402-E455 IonicContact NH2-OE1 2.86Å; R402-E455 PolarHBondContact NH2-OE1 2.77Å; F451-E455 WeakPolarHBondContact O-CG 3.49Å; F451-E455 PolarHBondContact O-N 3.06Å; V452-E455 PolarHBondContact O-N 3.18Å; N453-E455 VanDerWaalsContact C-N 3.31Å; N453-E455 PolarHBondContact O-N 2.6Å; E455-T516 HydrophobicContact CB-CG2 3.99Å; E455-T516 WeakPolarHBondContact OE2-CB 3.34Å; E455-T516 PolarHBondContact OE2-OG1 2.9Å; E455-L521 HydrophobicContact CB-CD2 4.22Å; E455-L521 HydrophobicContact CG-CD2 4.21Å; E455-P522 WeakPolarHBondContact O-CD 3.28Å
456L86.8Confident84.1Confident11 Ų1126.8 Ų26.86%0.05814%0.14CC..Hα-helixtrans-82.2-22.5-177.6-76.5172.5000114.2L350 V452 N453 L513 P514 T516 I528L350-L456 HydrophobicContact CD1-CD1 3.99Å; L350-L456 HydrophobicContact CD2-CD1 4.35Å; L350-L456 HydrophobicContact CG-CD1 4.43Å; V452-L456 HydrophobicContact CG1-CD1 3.49Å; V452-L456 VanDerWaalsContact CG1-CD1 3.49Å; V452-L456 HydrophobicContact CG1-CG 4.11Å; V452-L456 WeakPolarHBondContact O-CB 3.33Å; V452-L456 VanDerWaalsContact O-CG 3.3Å; V452-L456 WeakPolarHBondContact O-CG 3.46Å; V452-L456 PolarHBondContact O-N 3.49Å; N453-L456 PolarHBondContact O-N 3.18Å; L456-L513 HydrophobicContact CD1-CD1 4.29Å; L456-L513 HydrophobicContact CD1-CD2 4.17Å; L456-P514 HydrophobicContact CD2-CG 3.65Å; L456-T516 HydrophobicContact CD2-CG2 3.86Å; L456-T516 HydrophobicContact CG-CG2 4.16Å; L456-I528 VanDerWaalsContact O-CD1 3.28Å; L456-I528 WeakPolarHBondContact O-CD1 3.19Å
457Y84.4Confident83.7Confident1 Ų127.3 Ų27.30%0.00415%0.149CC..SBendtrans-93.1143.5-177.6-75.7-75000113.3L337 M343 T347 L350 N453 R462L337-Y457 HydrophobicContact CD2-CD1 4.24Å; L337-Y457 HydrophobicContact CD2-CE1 3.39Å; L337-Y457 HydrophobicContact CG-CE1 4.42Å; M343-Y457 HydrophobicContact CE-CD1 3.61Å; M343-Y457 HydrophobicContact CE-CE1 3.72Å; T347-Y457 WeakPolarHBondContact CA-OH 3.38Å; T347-Y457 WeakPolarHBondContact CB-OH 3.45Å; T347-Y457 WeakPolarHBondContact CG2-OH 3.27Å; T347-Y457 PolarHBondContact OG1-OH 2.98Å; L350-Y457 HydrophobicContact CD1-CE2 3.71Å; N453-Y457 WeakPolarHBondContact O-CD2 3.36Å; N453-Y457 WeakPolarHBondContact OD1-CD2 3.45Å; N453-Y457 WeakPolarHBondContact OD1-CE2 3.2Å; Y457-R462 PolarHBondContact O-NE 3.07Å; Y457-R462 VanDerWaalsContact O-NE 3.15Å; Y457-R462 PolarHBondContact O-NH2 3.11Å; Y457-R462 VanDerWaalsContact O-NH2 3.09Å
458P80.4Confident83.6Confident0 Ų027.9 Ų27.90%015%0.153CC..  trans-69.7148.5178.330.5-30.4000110.2M343 F460 V461 R462 P522 I525 I528M343-P458 HydrophobicContact CE-CG 4.44Å; P458-F460 HydrophobicContact CB-CD1 4.19Å; P458-F460 HydrophobicContact CB-CE1 4.12Å; P458-F460 HydrophobicContact CG-CD1 4.32Å; P458-F460 HydrophobicContact CG-CE1 3.99Å; P458-F460 PolarHBondContact O-N 3.37Å; P458-V461 HydrophobicContact CG-CB 4.2Å; P458-V461 HydrophobicContact CG-CG2 4.2Å; P458-V461 PolarHBondContact O-N 3.12Å; P458-R462 WeakPolarHBondContact O-CB 3.49Å; P458-R462 PolarHBondContact O-N 3.39Å; P458-P522 VanDerWaalsContact CA-O 3.25Å; P458-P522 WeakPolarHBondContact CA-O 3.36Å; P458-P522 HydrophobicContact CB-CB 4.38Å; P458-I525 HydrophobicContact CG-CG1 4.15Å; P458-I528 HydrophobicContact CB-CD1 4.28Å; P458-I528 HydrophobicContact CG-CD1 4.06Å
459T73.8Confident83.6Confident62 Ų6227.9 Ų27.938%0.3815%0.153SC..THydrogen-bonded Turntrans-50.3-40.3-169.3-55.30000113.8R462 P522T459-R462 PolarHBondContact OG1-NH2 3.42Å; T459-P522 PolarHBondContact N-O 3.16Å; T459-P522 VanDerWaalsContact N-O 3.15Å; T459-P522 PolarHBondContact OG1-O 3.46Å
460F73.1Confident83.3Confident52 Ų5228.6 Ų28.623%0.22816%0.158CC..THydrogen-bonded Turntrans-74.2-27.1-178.780-82.9000114.9T329 A332 P458 I525T329-F460 HydrophobicContact CG2-CB 4.35Å; A332-F460 HydrophobicContact CB-CD2 4.47Å; A332-F460 WeakPolarHBondContact CB-O 3.43Å; P458-F460 HydrophobicContact CB-CD1 4.19Å; P458-F460 HydrophobicContact CB-CE1 4.12Å; P458-F460 HydrophobicContact CG-CD1 4.32Å; P458-F460 HydrophobicContact CG-CE1 3.99Å; P458-F460 PolarHBondContact O-N 3.37Å; F460-I525 HydrophobicContact CE1-CD1 4.4Å; F460-I525 HydrophobicContact CE1-CG1 4.01Å; F460-I525 HydrophobicContact CZ-CD1 3.66Å; F460-I525 HydrophobicContact CZ-CG1 3.78Å
461V79.2Confident83.4Confident0 Ų028 Ų280%016%0.155CC..THydrogen-bonded Turntrans-103.2-10.1178.3-1660000111.9A332 D336 L337 P458 N463 L464 G465A332-V461 HydrophobicContact CB-CG2 4.31Å; D336-V461 HydrophobicContact CB-CG2 4.41Å; L337-V461 HydrophobicContact CD1-CG1 3.98Å; L337-V461 HydrophobicContact CD2-CG1 4.49Å; L337-V461 HydrophobicContact CG-CG1 3.92Å; P458-V461 HydrophobicContact CG-CB 4.2Å; P458-V461 HydrophobicContact CG-CG2 4.2Å; P458-V461 PolarHBondContact O-N 3.12Å; V461-N463 PolarHBondContact O-N 3.33Å; V461-L464 HydrophobicContact CG1-CB 4.34Å; V461-L464 HydrophobicContact CG1-CD2 4.38Å; V461-L464 WeakPolarHBondContact O-CB 3.5Å; V461-L464 PolarHBondContact O-N 3.16Å; V461-G465 PolarHBondContact O-N 3.09Å
462R79.7Confident83.8Confident38 Ų3829 Ų2914%0.14316%0.161CC..Hα-helixtrans-51.4-51-171.9-176.4179-64.1144.610113.6T454 Y457 P458 T459 L464 G465 V466T454-R462 WeakPolarHBondContact O-CD 3.4Å; T454-R462 PolarHBondContact O-NE 2.86Å; Y457-R462 PolarHBondContact O-NE 3.07Å; Y457-R462 VanDerWaalsContact O-NE 3.15Å; Y457-R462 PolarHBondContact O-NH2 3.11Å; Y457-R462 VanDerWaalsContact O-NH2 3.09Å; P458-R462 WeakPolarHBondContact O-CB 3.49Å; P458-R462 PolarHBondContact O-N 3.39Å; T459-R462 PolarHBondContact OG1-NH2 3.42Å; R462-L464 VanDerWaalsContact C-N 3.34Å; R462-L464 PolarHBondContact O-N 3.32Å; R462-G465 PolarHBondContact O-N 3.24Å; R462-V466 HydrophobicContact CG-CG2 4.45Å; R462-V466 WeakPolarHBondContact O-CB 3.25Å; R462-V466 WeakPolarHBondContact O-CG2 3.32Å; R462-V466 PolarHBondContact O-N 2.69Å
463N75.6Confident83.9Confident136 Ų13629.3 Ų29.373%0.72716%0.163SC*.Hα-helixtrans-64.8-40-178.5-67.1-18.7000111.7V461 S467V461-N463 PolarHBondContact O-N 3.33Å; N463-S467 WeakPolarHBondContact O-CB 3.3Å; N463-S467 PolarHBondContact O-N 2.82Å
464L81Confident84Confident37 Ų3729.5 Ų29.519%0.19416%0.164CC..Hα-helixtrans-64.9-46.5176.5-17765.9000111.4A332 F334 L337 V461 R462 S467 V468A332-L464 HydrophobicContact CB-CD2 4.02Å; F334-L464 HydrophobicContact CD1-CD1 4.19Å; F334-L464 HydrophobicContact CE1-CD1 3.74Å; F334-L464 HydrophobicContact CE2-CD1 4.4Å; F334-L464 HydrophobicContact CZ-CD1 3.86Å; L337-L464 HydrophobicContact CD1-CD2 3.71Å; L337-L464 HydrophobicContact CD1-CG 3.86Å; V461-L464 HydrophobicContact CG1-CB 4.34Å; V461-L464 HydrophobicContact CG1-CD2 4.38Å; V461-L464 WeakPolarHBondContact O-CB 3.5Å; V461-L464 PolarHBondContact O-N 3.16Å; R462-L464 VanDerWaalsContact C-N 3.34Å; R462-L464 PolarHBondContact O-N 3.32Å; L464-S467 WeakPolarHBondContact O-CB 3.42Å; L464-S467 PolarHBondContact O-N 2.77Å; L464-V468 HydrophobicContact CD1-CG2 4.47Å; L464-V468 WeakPolarHBondContact O-CG2 3.08Å; L464-V468 PolarHBondContact O-N 3.02Å
465G83.8Confident84.6Confident0 Ų030.4 Ų30.40%017%0.166CC..Hα-helixtrans-64.1-41.2179.100000113.3V461 R462 V468 C469V461-G465 PolarHBondContact O-N 3.09Å; R462-G465 PolarHBondContact O-N 3.24Å; G465-V468 PolarHBondContact O-N 3.49Å; G465-C469 WeakPolarHBondContact O-CB 3.45Å; G465-C469 PolarHBondContact O-N 3.4Å; G465-C469 PolarHBondContact O-SG 3.4Å
466V84.8Confident85Confident30 Ų3029 Ų2918%0.18216%0.16CC..Hα-helixtrans-61.6-46.3173.91730000110.8N453 T454 R462 C469 S470N453-V466 HydrophobicContact CB-CG2 4.42Å; N453-V466 WeakPolarHBondContact ND2-CA 3.5Å; T454-V466 HydrophobicContact CG2-CG2 3.79Å; R462-V466 HydrophobicContact CG-CG2 4.45Å; R462-V466 WeakPolarHBondContact O-CB 3.25Å; R462-V466 WeakPolarHBondContact O-CG2 3.32Å; R462-V466 PolarHBondContact O-N 2.69Å; V466-C469 PolarHBondContact O-N 3.47Å; V466-S470 VanDerWaalsContact O-CB 3.27Å; V466-S470 WeakPolarHBondContact O-CB 3.35Å; V466-S470 PolarHBondContact O-N 3.42Å; V466-S470 PolarHBondContact O-OG 3.2Å
467S83.8Confident85.3Confident50 Ų5028.5 Ų28.535%0.3516%0.157SC..Hα-helixtrans-59.2-51.1177.9-171.20000111.9N463 L464 C469 S470 T471N463-S467 WeakPolarHBondContact O-CB 3.3Å; N463-S467 PolarHBondContact O-N 2.82Å; L464-S467 WeakPolarHBondContact O-CB 3.42Å; L464-S467 PolarHBondContact O-N 2.77Å; S467-C469 PolarHBondContact O-N 2.94Å; S467-S470 WeakPolarHBondContact CA-OG 3.47Å; S467-S470 PolarHBondContact O-N 3.29Å; S467-S470 PolarHBondContact O-OG 2.95Å; S467-T471 PolarHBondContact O-N 3.44Å; S467-T471 PolarHBondContact O-OG1 3.3Å; S467-T471 VanDerWaalsContact O-OG1 3.13Å
468V87.3Confident85.9Confident29 Ų2930.3 Ų30.318%0.17617%0.167CC..Hα-helixtrans-58.8-46.6-180170.50000111.5F334 M351 L464 G465 S470 T471F334-V468 HydrophobicContact CD1-CG2 3.68Å; F334-V468 HydrophobicContact CE1-CG2 3.46Å; F334-V468 VanDerWaalsContact CE1-CG2 3.46Å; M351-V468 HydrophobicContact SD-CG1 4.49Å; L464-V468 HydrophobicContact CD1-CG2 4.47Å; L464-V468 WeakPolarHBondContact O-CG2 3.08Å; L464-V468 PolarHBondContact O-N 3.02Å; G465-V468 PolarHBondContact O-N 3.49Å; V468-S470 VanDerWaalsContact C-N 3.34Å; V468-T471 WeakPolarHBondContact O-CB 3.35Å; V468-T471 PolarHBondContact O-N 3.34Å
469C88.9Confident86.6Confident0 Ų033.1 Ų33.10%018%0.183CC..Hα-helixtrans-66.6-38.7178.8-63.10000111.5M351 W354 G465 V466 S467 T471 L472M351-C469 HydrophobicContact CG-CB 4.34Å; W354-C469 VanDerWaalsContact CB-O 3.27Å; W354-C469 WeakPolarHBondContact CB-O 3.44Å; W354-C469 VanDerWaalsContact CD1-CB 3.43Å; W354-C469 HydrophobicContact CG-CB 4.29Å; G465-C469 WeakPolarHBondContact O-CB 3.45Å; G465-C469 PolarHBondContact O-N 3.4Å; G465-C469 PolarHBondContact O-SG 3.4Å; V466-C469 PolarHBondContact O-N 3.47Å; S467-C469 PolarHBondContact O-N 2.94Å; C469-T471 VanDerWaalsContact C-N 3.33Å; C469-T471 PolarHBondContact O-N 3.21Å; C469-L472 WeakPolarHBondContact O-CB 3.27Å; C469-L472 PolarHBondContact O-N 2.97Å
470S86Confident87.6Confident15 Ų1530.1 Ų30.111%0.10517%0.165CC..Hα-helixtrans-68.3-28177.675.90000113.3V466 S467 V468 L472 C473 D474V466-S470 VanDerWaalsContact O-CB 3.27Å; V466-S470 WeakPolarHBondContact O-CB 3.35Å; V466-S470 PolarHBondContact O-N 3.42Å; V466-S470 PolarHBondContact O-OG 3.2Å; S467-S470 WeakPolarHBondContact CA-OG 3.47Å; S467-S470 PolarHBondContact O-N 3.29Å; S467-S470 PolarHBondContact O-OG 2.95Å; V468-S470 VanDerWaalsContact C-N 3.34Å; S470-L472 PolarHBondContact O-N 3.01Å; S470-C473 WeakPolarHBondContact O-CA 3.46Å; S470-C473 WeakPolarHBondContact O-CB 3.38Å; S470-C473 PolarHBondContact O-N 3.38Å; S470-D474 PolarHBondContact O-N 3.38Å
471T89.9Confident88.5Confident29 Ų2927.7 Ų27.718%0.17816%0.155CC..Hα-helixtrans-59.3-35.1172.3-65.20000111.7L162 S467 V468 C469 C473 D474 I475L162-T471 HydrophobicContact CD1-CG2 3.33Å; S467-T471 PolarHBondContact O-N 3.44Å; S467-T471 PolarHBondContact O-OG1 3.3Å; S467-T471 VanDerWaalsContact O-OG1 3.13Å; V468-T471 WeakPolarHBondContact O-CB 3.35Å; V468-T471 PolarHBondContact O-N 3.34Å; C469-T471 VanDerWaalsContact C-N 3.33Å; C469-T471 PolarHBondContact O-N 3.21Å; T471-C473 PolarHBondContact O-N 3.42Å; T471-D474 PolarHBondContact O-N 3.25Å; T471-I475 HydrophobicContact CG2-CD1 4.41Å; T471-I475 PolarHBondContact O-N 2.96Å; T471-I475 VanDerWaalsContact O-N 3.12Å
472L92.6Very high89.2Confident42 Ų4230.8 Ų30.822%0.2217%0.168CC..Hα-helixtrans-69.5-23.5175.2-86.9-68.9000112.6M351 F355 C469 S470 I475 G476M351-L472 HydrophobicContact CB-CG 4.27Å; M351-L472 HydrophobicContact CE-CD2 3.42Å; M351-L472 VanDerWaalsContact CE-CD2 3.42Å; M351-L472 HydrophobicContact CE-CG 3.77Å; M351-L472 HydrophobicContact CG-CG 4.5Å; F355-L472 WeakPolarHBondContact CA-O 3.17Å; F355-L472 HydrophobicContact CB-CB 4.37Å; C469-L472 WeakPolarHBondContact O-CB 3.27Å; C469-L472 PolarHBondContact O-N 2.97Å; S470-L472 PolarHBondContact O-N 3.01Å; L472-I475 HydrophobicContact CD1-CD1 4.13Å; L472-I475 HydrophobicContact CD2-CD1 4.45Å; L472-G476 PolarHBondContact O-N 3.47Å
473C92.3Very high89.8Confident11 Ų1130.7 Ų30.77%0.07417%0.17CC..Hα-helixtrans-62.2-48.8168-173.20000110.9W354 A358 F446 S470 T471 I475 G476 G477W354-C473 HydrophobicContact CB-CB 4.32Å; W354-C473 HydrophobicContact CD2-CB 4.28Å; W354-C473 HydrophobicContact CE3-CB 3.48Å; W354-C473 VanDerWaalsContact CE3-CB 3.48Å; W354-C473 HydrophobicContact CZ3-CB 4.09Å; A358-C473 HydrophobicContact CB-CB 4.37Å; A358-C473 WeakPolarHBondContact CB-O 3.47Å; A358-C473 VanDerWaalsContact CB-SG 3.58Å; F446-C473 VanDerWaalsContact CE2-SG 3.52Å; F446-C473 VanDerWaalsContact CZ-SG 3.56Å; S470-C473 WeakPolarHBondContact O-CA 3.46Å; S470-C473 WeakPolarHBondContact O-CB 3.38Å; S470-C473 PolarHBondContact O-N 3.38Å; T471-C473 PolarHBondContact O-N 3.42Å; C473-I475 VanDerWaalsContact C-N 3.31Å; C473-I475 PolarHBondContact O-N 3.43Å; C473-G476 WeakPolarHBondContact O-CA 3.26Å; C473-G476 PolarHBondContact O-N 3.16Å; C473-G476 VanDerWaalsContact O-N 3.12Å; C473-G477 PolarHBondContact O-N 3.17Å
474D92.1Very high90.6Very high4 Ų424.3 Ų24.32%0.02114%0.136CC..Hα-helixtrans-65.6-37.7-177.9-59-42.9000110.4L162 K216 S470 T471 G477 I478L162-D474 HydrophobicContact CB-CB 3.9Å; L162-D474 HydrophobicContact CD1-CB 4.29Å; K216-D474 IonicContact NZ-OD1 3.17Å; K216-D474 PolarHBondContact NZ-OD1 3.41Å; K216-D474 IonicContact NZ-OD2 3.47Å; S470-D474 PolarHBondContact O-N 3.38Å; T471-D474 PolarHBondContact O-N 3.25Å; D474-G477 PolarHBondContact O-N 3.2Å; D474-I478 WeakPolarHBondContact O-CG1 3.3Å; D474-I478 PolarHBondContact O-N 3.03Å
475I94.7Very high91Very high63 Ų6324.7 Ų24.732%0.32314%0.135SC..Hα-helixtrans-61.5-43.2171.5-64.4169.6000111.3L162 F355 T471 L472 C473 G477 I478 V479L162-I475 HydrophobicContact CD2-CG1 4.49Å; F355-I475 HydrophobicContact CD2-CG2 4.5Å; F355-I475 HydrophobicContact CE2-CG2 4.21Å; T471-I475 HydrophobicContact CG2-CD1 4.41Å; T471-I475 PolarHBondContact O-N 2.96Å; T471-I475 VanDerWaalsContact O-N 3.12Å; L472-I475 HydrophobicContact CD1-CD1 4.13Å; L472-I475 HydrophobicContact CD2-CD1 4.45Å; C473-I475 VanDerWaalsContact C-N 3.31Å; C473-I475 PolarHBondContact O-N 3.43Å; I475-G477 VanDerWaalsContact C-N 3.29Å; I475-G477 PolarHBondContact O-N 3.23Å; I475-I478 WeakPolarHBondContact O-CB 3.49Å; I475-I478 PolarHBondContact O-N 3.18Å; I475-I478 VanDerWaalsContact O-N 3.17Å; I475-V479 WeakPolarHBondContact O-CG2 3.38Å; I475-V479 PolarHBondContact O-N 2.95Å; I475-V479 VanDerWaalsContact O-N 3.14Å
476G94.8Very high91.3Very high0 Ų029.8 Ų29.80%016%0.155CC..Hα-helixtrans-58-42.2173.700000112.1I359 L472 C473 I478 V479 A480I359-G476 VanDerWaalsContact CG1-O 3.29Å; I359-G476 WeakPolarHBondContact CG1-O 3.33Å; L472-G476 PolarHBondContact O-N 3.47Å; C473-G476 WeakPolarHBondContact O-CA 3.26Å; C473-G476 PolarHBondContact O-N 3.16Å; C473-G476 VanDerWaalsContact O-N 3.12Å; G476-I478 VanDerWaalsContact C-N 3.34Å; G476-I478 PolarHBondContact O-N 3.45Å; G476-V479 PolarHBondContact O-N 3.35Å; G476-A480 WeakPolarHBondContact O-CB 3.25Å; G476-A480 PolarHBondContact O-N 3.11Å
477G93.8Very high91.5Very high0 Ų029.7 Ų29.70%015%0.153CC..Hα-helixtrans-64.3-32.3175.400000114.3N158 Q362 C473 D474 I475 P481N158-G477 VanDerWaalsContact ND2-C 3.27Å; N158-G477 PolarHBondContact ND2-O 3.38Å; Q362-G477 PolarHBondContact NE2-O 3.2Å; Q362-G477 VanDerWaalsContact NE2-O 3.1Å; C473-G477 PolarHBondContact O-N 3.17Å; D474-G477 PolarHBondContact O-N 3.2Å; I475-G477 VanDerWaalsContact C-N 3.29Å; I475-G477 PolarHBondContact O-N 3.23Å; G477-P481 WeakPolarHBondContact O-CD 3.43Å
478I95.8Very high91.6Very high39 Ų3928.2 Ų28.220%0.214%0.144CC..Hα-helixtrans-66.5-41.3173.2-65.5166.9000110.7A155 N158 V159 D474 I475 G476 P481 F482A155-I478 HydrophobicContact CB-CG2 4.27Å; N158-I478 HydrophobicContact CB-CB 4.5Å; N158-I478 HydrophobicContact CB-CG1 3.6Å; V159-I478 HydrophobicContact CB-CD1 4.43Å; V159-I478 HydrophobicContact CG2-CD1 3.61Å; V159-I478 HydrophobicContact CG2-CG1 3.97Å; D474-I478 WeakPolarHBondContact O-CG1 3.3Å; D474-I478 PolarHBondContact O-N 3.03Å; I475-I478 WeakPolarHBondContact O-CB 3.49Å; I475-I478 PolarHBondContact O-N 3.18Å; I475-I478 VanDerWaalsContact O-N 3.17Å; G476-I478 VanDerWaalsContact C-N 3.34Å; G476-I478 PolarHBondContact O-N 3.45Å; I478-P481 WeakPolarHBondContact O-CD 3.38Å; I478-F482 WeakPolarHBondContact O-CD2 3.38Å
479V95.6Very high91.4Very high58 Ų5831.6 Ų31.635%0.35216%0.164SC..Hα-helixtrans-78.4-31.1-176.9176.40000112.2I359 I475 G476 F482 L483I359-V479 HydrophobicContact CD1-CG1 4.48Å; I475-V479 WeakPolarHBondContact O-CG2 3.38Å; I475-V479 PolarHBondContact O-N 2.95Å; I475-V479 VanDerWaalsContact O-N 3.14Å; G476-V479 PolarHBondContact O-N 3.35Å; V479-F482 PolarHBondContact O-N 3.17Å; V479-L483 HydrophobicContact CG1-CB 4.43Å; V479-L483 WeakPolarHBondContact O-CB 3.35Å; V479-L483 PolarHBondContact O-N 2.87Å
480A94.5Very high91.3Very high0 Ų037.9 Ų37.90%020%0.197CC..Hα-helixtrans-55.4-45.2-171.700000115.4I359 Q362 M366 G476 L483 L484I359-A480 HydrophobicContact CG1-CB 4.41Å; Q362-A480 HydrophobicContact CB-CB 4.11Å; Q362-A480 HydrophobicContact CG-CB 4.49Å; M366-A480 HydrophobicContact CE-CB 4Å; G476-A480 WeakPolarHBondContact O-CB 3.25Å; G476-A480 PolarHBondContact O-N 3.11Å; A480-L483 PolarHBondContact O-N 2.71Å; A480-L484 WeakPolarHBondContact O-CB 3.43Å; A480-L484 PolarHBondContact O-N 3.49Å
481P92.9Very high91.2Very high0 Ų043.3 Ų43.30%022%0.215CC..Hα-helixtrans-62.3-48.1179.7-20.131.6000111.4D151 Q154 M366 G477 I478 L483 L484 Y485D151-P481 HydrophobicContact CB-CB 4.15Å; Q154-P481 HydrophobicContact CB-CB 4.36Å; Q154-P481 HydrophobicContact CB-CG 3.69Å; Q154-P481 HydrophobicContact CG-CG 3.91Å; M366-P481 HydrophobicContact CE-CB 4.11Å; M366-P481 HydrophobicContact CE-CG 3.92Å; M366-P481 HydrophobicContact SD-CB 4.01Å; M366-P481 HydrophobicContact SD-CG 3.9Å; G477-P481 WeakPolarHBondContact O-CD 3.43Å; I478-P481 WeakPolarHBondContact O-CD 3.38Å; P481-L483 VanDerWaalsContact C-N 3.35Å; P481-L483 PolarHBondContact O-N 3.37Å; P481-L484 PolarHBondContact O-N 3.18Å; P481-L484 VanDerWaalsContact O-N 3.17Å; P481-Y485 HydrophobicContact CB-CD2 4.3Å; P481-Y485 HydrophobicContact CB-CE2 4.39Å; P481-Y485 WeakPolarHBondContact O-CD2 3.49Å; P481-Y485 PolarHBondContact O-N 3.41Å
482F92.9Very high91Very high65 Ų6545 Ų4529%0.28522%0.223SC..Hα-helixtrans-62.2-42.9178-61.6-71.9000111.8D151 M152 A155 I478 V479 L484 R486D151-F482 HydrophobicContact CB-CD1 3.58Å; D151-F482 HydrophobicContact CB-CE1 3.51Å; D151-F482 HydrophobicContact CB-CG 4.26Å; D151-F482 HydrophobicContact CB-CZ 4.15Å; M152-F482 HydrophobicContact CG-CE1 4.45Å; M152-F482 HydrophobicContact CG-CZ 4.15Å; A155-F482 HydrophobicContact CB-CD2 4.43Å; A155-F482 HydrophobicContact CB-CE2 3.48Å; A155-F482 VanDerWaalsContact CB-CE2 3.48Å; A155-F482 HydrophobicContact CB-CZ 3.98Å; I478-F482 WeakPolarHBondContact O-CD2 3.38Å; V479-F482 PolarHBondContact O-N 3.17Å; F482-L484 VanDerWaalsContact C-N 3.26Å; F482-L484 PolarHBondContact O-N 2.95Å; F482-R486 WeakPolarHBondContact O-CB 3.4Å; F482-R486 VanDerWaalsContact O-CG 3.27Å; F482-R486 WeakPolarHBondContact O-CG 3.16Å; F482-R486 PolarHBondContact O-N 2.95Å; F482-R486 VanDerWaalsContact O-N 3.16Å
483L93.5Very high90.8Very high37 Ų3743.7 Ų43.719%0.19422%0.216CC..Hα-helixtrans-63.2-35.3178-16972.4000111.5I359 V479 A480 P481 L487 I498 F499I359-L483 HydrophobicContact CG2-CD2 3.73Å; V479-L483 HydrophobicContact CG1-CB 4.43Å; V479-L483 WeakPolarHBondContact O-CB 3.35Å; V479-L483 PolarHBondContact O-N 2.87Å; A480-L483 PolarHBondContact O-N 2.71Å; P481-L483 VanDerWaalsContact C-N 3.35Å; P481-L483 PolarHBondContact O-N 3.37Å; L483-L487 HydrophobicContact CD1-CD1 4.43Å; L483-L487 HydrophobicContact CD1-CD2 4.08Å; L483-L487 HydrophobicContact CG-CD2 4.44Å; L483-L487 WeakPolarHBondContact O-CB 3.13Å; L483-L487 WeakPolarHBondContact O-CD1 3.45Å; L483-I498 HydrophobicContact CD1-CD1 4.49Å; L483-I498 HydrophobicContact CD1-CG2 4.5Å; L483-I498 HydrophobicContact CD2-CG2 4.12Å; L483-F499 HydrophobicContact CD2-CD1 4.08Å; L483-F499 HydrophobicContact CD2-CE1 3.58Å; L483-F499 HydrophobicContact CG-CE1 4.21Å
484L92.8Very high90.8Very high1 Ų145.5 Ų45.51%0.00522%0.224CC..Hα-helixtrans-74.3-63.9177.5178.371.8000111.7M366 R367 I370 A480 P481 F482 R486 L487 A488 P495 F499M366-L484 VanDerWaalsContact C-CD2 3.49Å; M366-L484 HydrophobicContact CB-CD2 3.28Å; M366-L484 HydrophobicContact CE-CD2 4.4Å; R367-L484 HydrophobicContact CB-CD1 3.96Å; R367-L484 HydrophobicContact CB-CD2 4.39Å; R367-L484 HydrophobicContact CG-CD1 4.39Å; I370-L484 HydrophobicContact CD1-CD1 4.3Å; I370-L484 HydrophobicContact CD1-CG 4.32Å; A480-L484 WeakPolarHBondContact O-CB 3.43Å; A480-L484 PolarHBondContact O-N 3.49Å; P481-L484 PolarHBondContact O-N 3.18Å; P481-L484 VanDerWaalsContact O-N 3.17Å; F482-L484 VanDerWaalsContact C-N 3.26Å; F482-L484 PolarHBondContact O-N 2.95Å; L484-R486 PolarHBondContact O-N 3.19Å; L484-L487 PolarHBondContact O-N 3.13Å; L484-A488 VanDerWaalsContact O-CB 3.32Å; L484-A488 WeakPolarHBondContact O-CB 3.46Å; L484-A488 PolarHBondContact O-N 3.17Å; L484-P495 HydrophobicContact CD1-CB 3.76Å; L484-P495 HydrophobicContact CD1-CG 3.96Å; L484-P495 WeakPolarHBondContact O-CG 3.47Å; L484-F499 HydrophobicContact CB-CZ 4.35Å; L484-F499 HydrophobicContact CD1-CE2 4.12Å; L484-F499 HydrophobicContact CD1-CZ 4.26Å
485Y88.6Confident90.8Very high45 Ų4545.3 Ų45.318%0.17622%0.223CC..Hα-helixtrans-69.2-38.9-166.9-67.7-69.4000112.1D151 M366 I370 P481 L487 A488 T489D151-Y485 WeakPolarHBondContact OD1-CB 3.25Å; D151-Y485 WeakPolarHBondContact OD1-CD2 3.19Å; M366-Y485 HydrophobicContact CB-CE2 4.48Å; M366-Y485 HydrophobicContact SD-CE2 4.23Å; I370-Y485 HydrophobicContact CG2-CD1 4.11Å; I370-Y485 HydrophobicContact CG2-CE1 3.59Å; P481-Y485 HydrophobicContact CB-CD2 4.3Å; P481-Y485 HydrophobicContact CB-CE2 4.39Å; P481-Y485 WeakPolarHBondContact O-CD2 3.49Å; P481-Y485 PolarHBondContact O-N 3.41Å; Y485-L487 VanDerWaalsContact C-N 3.33Å; Y485-L487 PolarHBondContact O-N 3.1Å; Y485-A488 PolarHBondContact O-N 2.97Å; Y485-T489 PolarHBondContact O-N 3.21Å
486R89.4Confident90.8Very high108 Ų10842.3 Ų42.341%0.40821%0.208SC..Hα-helixtrans-71.6-26.4179.9-58.1-54.4-52.4-177.11.1113.8F482 L484 T489F482-R486 WeakPolarHBondContact O-CB 3.4Å; F482-R486 VanDerWaalsContact O-CG 3.27Å; F482-R486 WeakPolarHBondContact O-CG 3.16Å; F482-R486 PolarHBondContact O-N 2.95Å; F482-R486 VanDerWaalsContact O-N 3.16Å; L484-R486 PolarHBondContact O-N 3.19Å; R486-T489 PolarHBondContact O-OG1 3.42Å
487L88.7Confident90.8Very high28 Ų2845.3 Ų45.315%0.14722%0.223CC..Hα-helixtrans-84.1-34.5174.7-84.358.6000110.6L483 L484 Y485 T489 I490 W491 L494 P495 I498L483-L487 HydrophobicContact CD1-CD1 4.43Å; L483-L487 HydrophobicContact CD1-CD2 4.08Å; L483-L487 HydrophobicContact CG-CD2 4.44Å; L483-L487 WeakPolarHBondContact O-CB 3.13Å; L483-L487 WeakPolarHBondContact O-CD1 3.45Å; L484-L487 PolarHBondContact O-N 3.13Å; Y485-L487 VanDerWaalsContact C-N 3.33Å; Y485-L487 PolarHBondContact O-N 3.1Å; L487-T489 PolarHBondContact O-N 2.99Å; L487-I490 PolarHBondContact O-N 3.02Å; L487-W491 PolarHBondContact O-N 2.82Å; L487-W491 VanDerWaalsContact O-O 3.07Å; L487-L494 HydrophobicContact CB-CB 4.39Å; L487-L494 HydrophobicContact CB-CD2 4.1Å; L487-L494 HydrophobicContact CB-CG 4.34Å; L487-L494 HydrophobicContact CD2-CD2 4.33Å; L487-L494 HydrophobicContact CD2-CG 4.26Å; L487-L494 HydrophobicContact CG-CD2 3.96Å; L487-L494 HydrophobicContact CG-CG 4.36Å; L487-P495 HydrophobicContact CB-CG 3.75Å; L487-I498 HydrophobicContact CD2-CD1 3.25Å; L487-I498 HydrophobicContact CD2-CG1 4.07Å
488A86.3Confident90.8Very high19 Ų1948.1 Ų48.116%0.15724%0.238CC..Hα-helixtrans-59.9-31.4174.800000112.6I370 L484 Y485 I490 W491 L492 P495I370-A488 HydrophobicContact CD1-CB 3.83Å; L484-A488 VanDerWaalsContact O-CB 3.32Å; L484-A488 WeakPolarHBondContact O-CB 3.46Å; L484-A488 PolarHBondContact O-N 3.17Å; Y485-A488 PolarHBondContact O-N 2.97Å; A488-I490 VanDerWaalsContact C-N 3.29Å; A488-I490 PolarHBondContact O-N 3.29Å; A488-W491 CarbonylContact O-C 3.47Å; A488-L492 HydrophobicContact CB-CD1 4.26Å; A488-L492 PolarHBondContact O-N 2.96Å; A488-P495 HydrophobicContact CB-CG 4.36Å
489T83.5Confident90.8Very high99 Ų9946.3 Ų46.361%0.60723%0.228SC*.THydrogen-bonded Turntrans-67.2-26.5173.856.50000113.8Y485 R486 L487Y485-T489 PolarHBondContact O-N 3.21Å; R486-T489 PolarHBondContact O-OG1 3.42Å; L487-T489 PolarHBondContact O-N 2.99Å
490I86.3Confident90.9Very high132 Ų13243.5 Ų43.568%0.67721%0.211SC*.THydrogen-bonded Turntrans-83.4-52.1176.8-58.9170.6000108.9L487 A488 L494L487-I490 PolarHBondContact O-N 3.02Å; A488-I490 VanDerWaalsContact C-N 3.29Å; A488-I490 PolarHBondContact O-N 3.29Å; I490-L494 HydrophobicContact CB-CD2 4.44Å; I490-L494 HydrophobicContact CG2-CD2 4.49Å
491W84.9Confident91Very high129 Ų12945.3 Ų45.349%0.48923%0.226SC..  trans-155.3125.7173.5179.946.9000109.4L487 A488 E493 L494 I497L487-W491 PolarHBondContact O-N 2.82Å; L487-W491 VanDerWaalsContact O-O 3.07Å; A488-W491 CarbonylContact O-C 3.47Å; W491-E493 HydrophobicContact CD2-CB 4.15Å; W491-E493 HydrophobicContact CE3-CB 4.37Å; W491-E493 HydrophobicContact CH2-CB 3.97Å; W491-E493 HydrophobicContact CZ2-CB 3.72Å; W491-E493 HydrophobicContact CZ2-CG 4.25Å; W491-E493 HydrophobicContact CZ3-CB 4.31Å; W491-E493 PolarHBondContact O-N 2.82Å; W491-L494 HydrophobicContact CB-CB 4.19Å; W491-L494 HydrophobicContact CE3-CB 3.98Å; W491-L494 HydrophobicContact CE3-CD1 4.36Å; W491-L494 VanDerWaalsContact O-CB 3.25Å; W491-L494 WeakPolarHBondContact O-CB 3.29Å; W491-L494 PolarHBondContact O-N 2.83Å; W491-I497 HydrophobicContact CE3-CD1 4.46Å; W491-I497 HydrophobicContact CH2-CD1 4.09Å; W491-I497 HydrophobicContact CZ3-CD1 3.47Å; W491-I497 VanDerWaalsContact CZ3-CD1 3.47Å
492L85Confident91.2Very high66 Ų6646.8 Ų46.835%0.34623%0.234SC..THydrogen-bonded Turntrans-52.8-33.2-171.8-174.362.3000113.8I370 A488 P495I370-L492 HydrophobicContact CD1-CD1 3.95Å; I370-L492 HydrophobicContact CG1-CD1 4.36Å; A488-L492 HydrophobicContact CB-CD1 4.26Å; A488-L492 PolarHBondContact O-N 2.96Å; L492-P495 WeakPolarHBondContact O-CD 2.89Å
493E89.5Confident91.4Very high14 Ų1443.7 Ų43.77%0.06522%0.22CC..THydrogen-bonded Turntrans-92.8-9.6-176.7-60.2-61150.300113.9R367 A421 K431 W491 P495 L496R367-E493 IonicContact CZ-OE2 2.83Å; R367-E493 IonicContact NH2-OE1 3.71Å; R367-E493 PolarHBondContact NH2-OE1 3.3Å; R367-E493 IonicContact NH2-OE2 3.93Å; R367-E493 PolarHBondContact NH2-OE2 3.12Å; A421-E493 HydrophobicContact CB-CB 4.14Å; K431-E493 WeakPolarHBondContact CE-OE1 3.44Å; K431-E493 IonicContact NZ-OE1 3.84Å; K431-E493 PolarHBondContact NZ-OE1 3.12Å; W491-E493 HydrophobicContact CD2-CB 4.15Å; W491-E493 HydrophobicContact CE3-CB 4.37Å; W491-E493 HydrophobicContact CH2-CB 3.97Å; W491-E493 HydrophobicContact CZ2-CB 3.72Å; W491-E493 HydrophobicContact CZ2-CG 4.25Å; W491-E493 HydrophobicContact CZ3-CB 4.31Å; W491-E493 PolarHBondContact O-N 2.82Å; E493-P495 VanDerWaalsContact C-CD 3.42Å; E493-L496 WeakPolarHBondContact O-CB 3.41Å; E493-L496 PolarHBondContact O-N 3.44Å; E493-L496 VanDerWaalsContact O-N 3.15Å; E493-L496 WeakPolarHBondContact OE2-CD1 2.96Å
494L90.6Very high91.6Very high48 Ų4843.6 Ų43.625%0.25122%0.222SC..Hα-helixtrans-57.5-40.9-179.4-172.565.6000114.3L487 I490 W491 L496 I497 I498L487-L494 HydrophobicContact CB-CB 4.39Å; L487-L494 HydrophobicContact CB-CD2 4.1Å; L487-L494 HydrophobicContact CB-CG 4.34Å; L487-L494 HydrophobicContact CD2-CD2 4.33Å; L487-L494 HydrophobicContact CD2-CG 4.26Å; L487-L494 HydrophobicContact CG-CD2 3.96Å; L487-L494 HydrophobicContact CG-CG 4.36Å; I490-L494 HydrophobicContact CB-CD2 4.44Å; I490-L494 HydrophobicContact CG2-CD2 4.49Å; W491-L494 HydrophobicContact CB-CB 4.19Å; W491-L494 HydrophobicContact CE3-CB 3.98Å; W491-L494 HydrophobicContact CE3-CD1 4.36Å; W491-L494 VanDerWaalsContact O-CB 3.25Å; W491-L494 WeakPolarHBondContact O-CB 3.29Å; W491-L494 PolarHBondContact O-N 2.83Å; L494-L496 PolarHBondContact O-N 3.08Å; L494-I497 PolarHBondContact O-N 3.2Å; L494-I497 VanDerWaalsContact O-N 3.13Å; L494-I498 PolarHBondContact O-N 3.38Å
495P93.4Very high91.9Very high0 Ų048.1 Ų48.10%025%0.245CC..Hα-helixtrans-56.4-37.5176.7-22.631.1000113L484 L487 A488 L492 E493 I497 I498 F499L484-P495 HydrophobicContact CD1-CB 3.76Å; L484-P495 HydrophobicContact CD1-CG 3.96Å; L484-P495 WeakPolarHBondContact O-CG 3.47Å; L487-P495 HydrophobicContact CB-CG 3.75Å; A488-P495 HydrophobicContact CB-CG 4.36Å; L492-P495 WeakPolarHBondContact O-CD 2.89Å; E493-P495 VanDerWaalsContact C-CD 3.42Å; P495-I497 VanDerWaalsContact C-N 3.32Å; P495-I497 PolarHBondContact O-N 2.98Å; P495-I498 PolarHBondContact O-N 3.06Å; P495-F499 HydrophobicContact CB-CE2 4.05Å; P495-F499 HydrophobicContact CB-CZ 4.12Å; P495-F499 WeakPolarHBondContact O-CB 3.43Å; P495-F499 WeakPolarHBondContact O-CD1 3.25Å; P495-F499 WeakPolarHBondContact O-CD2 3.33Å; P495-F499 WeakPolarHBondContact O-CG 3.36Å; P495-F499 PolarHBondContact O-N 3.43Å
496L93.5Very high92.3Very high1 Ų146 Ų461%0.00524%0.237CC..Hα-helixtrans-64.3-36.9178.8-73.2-171.4000112.9L364 C417 T420 A421 E493 L494 I498 F499 G500L364-L496 HydrophobicContact CD2-CD2 3.72Å; C417-L496 HydrophobicContact CB-CB 4.33Å; C417-L496 HydrophobicContact CB-CD2 4.31Å; C417-L496 WeakPolarHBondContact CB-O 3.46Å; C417-L496 WeakPolarHBondContact O-CD1 3.5Å; T420-L496 HydrophobicContact CG2-CD1 3.74Å; A421-L496 HydrophobicContact CB-CB 4.19Å; A421-L496 HydrophobicContact CB-CD1 3.97Å; E493-L496 WeakPolarHBondContact O-CB 3.41Å; E493-L496 PolarHBondContact O-N 3.44Å; E493-L496 VanDerWaalsContact O-N 3.15Å; E493-L496 WeakPolarHBondContact OE2-CD1 2.96Å; L494-L496 PolarHBondContact O-N 3.08Å; L496-I498 VanDerWaalsContact C-N 3.29Å; L496-F499 HydrophobicContact CD2-CD2 4.39Å; L496-F499 PolarHBondContact O-N 3.41Å; L496-G500 WeakPolarHBondContact O-CA 3.05Å; L496-G500 PolarHBondContact O-N 3.4Å
497I94.9Very high92.6Very high62 Ų6240.8 Ų40.832%0.31822%0.217SC..Hα-helixtrans-64.4-42.3178.8-62.9-176.9000109.3F418 A421 W491 L494 P495 G500 A501F418-I497 HydrophobicContact CD1-CG2 4.34Å; F418-I497 HydrophobicContact CE1-CB 4.34Å; F418-I497 HydrophobicContact CE1-CG2 3.83Å; F418-I497 WeakPolarHBondContact CE1-O 3.18Å; A421-I497 HydrophobicContact CB-CG1 4.02Å; W491-I497 HydrophobicContact CE3-CD1 4.46Å; W491-I497 HydrophobicContact CH2-CD1 4.09Å; W491-I497 HydrophobicContact CZ3-CD1 3.47Å; W491-I497 VanDerWaalsContact CZ3-CD1 3.47Å; L494-I497 PolarHBondContact O-N 3.2Å; L494-I497 VanDerWaalsContact O-N 3.13Å; P495-I497 VanDerWaalsContact C-N 3.32Å; P495-I497 PolarHBondContact O-N 2.98Å; I497-G500 PolarHBondContact O-N 3.49Å; I497-A501 WeakPolarHBondContact O-CB 3.12Å; I497-A501 PolarHBondContact O-N 3.15Å
498I95.2Very high93Very high60 Ų6041.1 Ų41.131%0.30823%0.227SC..Hα-helixtrans-66.9-48.8176.5-58.5-161.9000110.8L483 L487 L494 P495 L496 G500 A501 I502L483-I498 HydrophobicContact CD1-CD1 4.49Å; L483-I498 HydrophobicContact CD1-CG2 4.5Å; L483-I498 HydrophobicContact CD2-CG2 4.12Å; L487-I498 HydrophobicContact CD2-CD1 3.25Å; L487-I498 HydrophobicContact CD2-CG1 4.07Å; L494-I498 PolarHBondContact O-N 3.38Å; P495-I498 PolarHBondContact O-N 3.06Å; L496-I498 VanDerWaalsContact C-N 3.29Å; I498-G500 PolarHBondContact O-N 3.11Å; I498-A501 PolarHBondContact O-N 3.07Å; I498-A501 VanDerWaalsContact O-N 3.15Å; I498-I502 HydrophobicContact CG2-CG2 4.4Å; I498-I502 WeakPolarHBondContact O-CG1 3.37Å; I498-I502 PolarHBondContact O-N 3.28Å
499F95.9Very high93.5Very high0 Ų042.9 Ų42.90%023%0.234CC..Hα-helixtrans-54.8-41.3174.7-64.4-16000111.5I359 V360 L364 L483 L484 P495 L496 I502 A503I359-F499 HydrophobicContact CG2-CD1 3.76Å; I359-F499 HydrophobicContact CG2-CE1 3.56Å; V360-F499 HydrophobicContact CG1-CB 4.31Å; V360-F499 HydrophobicContact CG2-CB 3.96Å; V360-F499 HydrophobicContact CG2-CD1 4.43Å; V360-F499 HydrophobicContact CG2-CG 4.33Å; L364-F499 HydrophobicContact CD2-CD2 4.44Å; L483-F499 HydrophobicContact CD2-CD1 4.08Å; L483-F499 HydrophobicContact CD2-CE1 3.58Å; L483-F499 HydrophobicContact CG-CE1 4.21Å; L484-F499 HydrophobicContact CB-CZ 4.35Å; L484-F499 HydrophobicContact CD1-CE2 4.12Å; L484-F499 HydrophobicContact CD1-CZ 4.26Å; P495-F499 HydrophobicContact CB-CE2 4.05Å; P495-F499 HydrophobicContact CB-CZ 4.12Å; P495-F499 WeakPolarHBondContact O-CB 3.43Å; P495-F499 WeakPolarHBondContact O-CD1 3.25Å; P495-F499 WeakPolarHBondContact O-CD2 3.33Å; P495-F499 WeakPolarHBondContact O-CG 3.36Å; P495-F499 PolarHBondContact O-N 3.43Å; L496-F499 HydrophobicContact CD2-CD2 4.39Å; L496-F499 PolarHBondContact O-N 3.41Å; F499-I502 HydrophobicContact CD1-CD1 4.41Å; F499-I502 VanDerWaalsContact O-CG1 3.29Å; F499-I502 WeakPolarHBondContact O-CG1 3.21Å; F499-A503 WeakPolarHBondContact O-CB 3.02Å; F499-A503 PolarHBondContact O-N 2.82Å
500G96.3Very high94.1Very high0 Ų038.1 Ų38.10%021%0.205CC..Hα-helixtrans-58.9-50.6175.700000112.5G414 F418 L496 I497 I498 C504G414-G500 WeakPolarHBondContact O-CA 3.45Å; F418-G500 VanDerWaalsContact CZ-C 3.43Å; L496-G500 WeakPolarHBondContact O-CA 3.05Å; L496-G500 PolarHBondContact O-N 3.4Å; I497-G500 PolarHBondContact O-N 3.49Å; I498-G500 PolarHBondContact O-N 3.11Å; G500-C504 WeakPolarHBondContact O-CB 3.04Å; G500-C504 PolarHBondContact O-N 3.1Å; G500-C504 PolarHBondContact O-SG 2.02Å
501A97.1Very high94.5Very high38 Ų3835.1 Ų35.131%0.31419%0.189SC..Hα-helixtrans-64-49.9-17900000111.8F418 I497 I498 A503 C504 I505F418-A501 HydrophobicContact CZ-CB 4.02Å; I497-A501 WeakPolarHBondContact O-CB 3.12Å; I497-A501 PolarHBondContact O-N 3.15Å; I498-A501 PolarHBondContact O-N 3.07Å; I498-A501 VanDerWaalsContact O-N 3.15Å; A501-A503 VanDerWaalsContact C-N 3.35Å; A501-A503 PolarHBondContact O-N 3.26Å; A501-C504 PolarHBondContact O-N 2.81Å; A501-I505 VanDerWaalsContact O-CG1 3.26Å; A501-I505 WeakPolarHBondContact O-CG1 3.36Å; A501-I505 PolarHBondContact O-N 3.29Å
502I97Very high94.9Very high30 Ų3033.4 Ų33.415%0.15419%0.19CC..Hα-helixtrans-64.3-39.6-17964.3178.1000111.6T356 I359 V360 I498 F499 I505 A506T356-I502 HydrophobicContact CG2-CB 4.23Å; T356-I502 HydrophobicContact CG2-CD1 4.27Å; T356-I502 HydrophobicContact CG2-CG1 3.93Å; I359-I502 HydrophobicContact CB-CD1 4.21Å; I359-I502 HydrophobicContact CG2-CD1 3.69Å; V360-I502 HydrophobicContact CG2-CD1 3.8Å; V360-I502 HydrophobicContact CG2-CG1 3.95Å; I498-I502 HydrophobicContact CG2-CG2 4.4Å; I498-I502 WeakPolarHBondContact O-CG1 3.37Å; I498-I502 PolarHBondContact O-N 3.28Å; F499-I502 HydrophobicContact CD1-CD1 4.41Å; F499-I502 VanDerWaalsContact O-CG1 3.29Å; F499-I502 WeakPolarHBondContact O-CG1 3.21Å; I502-I505 PolarHBondContact O-N 3.41Å; I502-A506 WeakPolarHBondContact O-CB 3.21Å; I502-A506 PolarHBondContact O-N 3.39Å
503A97.6Very high95.3Very high0 Ų030.5 Ų30.50%017%0.174CC..Hα-helixtrans-66.8-42.2177.700000112.1T356 V360 F499 A501 I505 A506 G507T356-A503 HydrophobicContact CG2-CB 4.43Å; V360-A503 HydrophobicContact CG2-CB 4.42Å; F499-A503 WeakPolarHBondContact O-CB 3.02Å; F499-A503 PolarHBondContact O-N 2.82Å; A501-A503 VanDerWaalsContact C-N 3.35Å; A501-A503 PolarHBondContact O-N 3.26Å; A503-I505 PolarHBondContact O-N 2.85Å; A503-A506 PolarHBondContact O-N 2.03Å; A503-G507 PolarHBondContact O-N 3.23Å
504C97.8Very high95.3Very high35 Ų3532.8 Ų32.824%0.23619%0.19CC..Hα-helixtrans-62.6-43.6175.5-69.60000111.8G500 A501 A506 G507 G508G500-C504 WeakPolarHBondContact O-CB 3.04Å; G500-C504 PolarHBondContact O-N 3.1Å; G500-C504 PolarHBondContact O-SG 2.02Å; A501-C504 PolarHBondContact O-N 2.81Å; C504-A506 VanDerWaalsContact C-N 3.35Å; C504-G507 PolarHBondContact O-N 3.05Å; C504-G508 PolarHBondContact O-N 3.46Å
505I97.9Very high95.2Very high96 Ų9633.4 Ų33.449%0.49219%0.192SC..Hα-helixtrans-62-45.1175.7-66.8165.7000110.1F352 A501 I502 A503 G507 G508 L509F352-I505 HydrophobicContact CE1-CB 4.34Å; F352-I505 HydrophobicContact CE1-CG2 3.86Å; F352-I505 HydrophobicContact CZ-CG2 4.13Å; A501-I505 VanDerWaalsContact O-CG1 3.26Å; A501-I505 WeakPolarHBondContact O-CG1 3.36Å; A501-I505 PolarHBondContact O-N 3.29Å; I502-I505 PolarHBondContact O-N 3.41Å; A503-I505 PolarHBondContact O-N 2.85Å; I505-G507 PolarHBondContact O-N 3.44Å; I505-G508 PolarHBondContact O-N 2.94Å; I505-L509 HydrophobicContact CG2-CD1 4.05Å; I505-L509 HydrophobicContact CG2-CG 4.4Å; I505-L509 WeakPolarHBondContact O-CG 3.16Å; I505-L509 PolarHBondContact O-N 3.46Å
506A97.1Very high94.8Very high0 Ų034.3 Ų34.30%020%0.198CC..Hα-helixtrans-59.3-47.8178.800000111.4F352 T356 I502 A503 C504 G508 L509 V510F352-A506 HydrophobicContact CD1-CB 4.01Å; F352-A506 HydrophobicContact CE1-CB 3.77Å; T356-A506 HydrophobicContact CG2-CB 3.81Å; I502-A506 WeakPolarHBondContact O-CB 3.21Å; I502-A506 PolarHBondContact O-N 3.39Å; A503-A506 PolarHBondContact O-N 2.03Å; C504-A506 VanDerWaalsContact C-N 3.35Å; A506-G508 PolarHBondContact O-N 3.4Å; A506-L509 PolarHBondContact O-N 3.07Å; A506-V510 WeakPolarHBondContact O-CG2 3.24Å; A506-V510 PolarHBondContact O-N 3.35Å
507G96.8Very high94.3Very high0 Ų039.4 Ų39.40%022%0.217CC..Hα-helixtrans-62.1-39.4176.100000113.5A407 A503 C504 I505 V510 L511A407-G507 WeakPolarHBondContact CB-O 3.38Å; A503-G507 PolarHBondContact O-N 3.23Å; C504-G507 PolarHBondContact O-N 3.05Å; I505-G507 PolarHBondContact O-N 3.44Å; G507-V510 WeakPolarHBondContact O-CB 3.43Å; G507-V510 PolarHBondContact O-N 3.47Å; G507-L511 PolarHBondContact O-N 2.87Å
508G96.8Very high93.1Very high34 Ų3440.4 Ų40.435%0.35124%0.243SC..Hα-helixtrans-62.3-41173.200000112.8C504 I505 A506 L511C504-G508 PolarHBondContact O-N 3.46Å; I505-G508 PolarHBondContact O-N 2.94Å; A506-G508 PolarHBondContact O-N 3.4Å; G508-L511 WeakPolarHBondContact O-CB 3.42Å; G508-L511 PolarHBondContact O-N 2.98Å
509L96.6Very high92.2Very high56 Ų5642.3 Ų42.329%0.29326%0.257SS..Hα-helixtrans-68.1-34.3175.9-69.7174.5000112.5I349 F352 I505 A506 L511 L512I349-L509 HydrophobicContact CG1-CB 4.39Å; I349-L509 HydrophobicContact CG2-CB 4.08Å; F352-L509 HydrophobicContact CD1-CD1 3.71Å; F352-L509 HydrophobicContact CE1-CD1 4.08Å; F352-L509 HydrophobicContact CG-CD1 4.43Å; I505-L509 HydrophobicContact CG2-CD1 4.05Å; I505-L509 HydrophobicContact CG2-CG 4.4Å; I505-L509 WeakPolarHBondContact O-CG 3.16Å; I505-L509 PolarHBondContact O-N 3.46Å; A506-L509 PolarHBondContact O-N 3.07Å; L509-L511 PolarHBondContact O-N 3.04Å; L509-L512 HydrophobicContact CD2-CD1 4.02Å; L509-L512 VanDerWaalsContact O-CB 3.29Å; L509-L512 WeakPolarHBondContact O-CB 3.31Å; L509-L512 PolarHBondContact O-N 3.05Å
510V95.9Very high91Very high0 Ų053.5 Ų53.50%030%0.299CS..Hα-helixtrans-59.9-33.2174.1170.50000111.5N353 F406 A407 A506 G507 L512 L513N353-V510 WeakPolarHBondContact ND2-CG2 3.22Å; N353-V510 VanDerWaalsContact OD1-CG2 3.25Å; N353-V510 WeakPolarHBondContact OD1-CG2 3.39Å; F406-V510 HydrophobicContact CB-CG1 4.01Å; F406-V510 HydrophobicContact CD1-CB 4.18Å; F406-V510 HydrophobicContact CD1-CG1 3.3Å; F406-V510 HydrophobicContact CD1-CG2 3.69Å; F406-V510 HydrophobicContact CD2-CG2 4.44Å; F406-V510 HydrophobicContact CE1-CB 4.24Å; F406-V510 HydrophobicContact CE1-CG1 3.81Å; F406-V510 HydrophobicContact CE1-CG2 3.3Å; F406-V510 HydrophobicContact CE2-CG2 4.09Å; F406-V510 HydrophobicContact CG-CG1 3.77Å; F406-V510 HydrophobicContact CG-CG2 4.21Å; F406-V510 HydrophobicContact CZ-CG2 3.49Å; F406-V510 VanDerWaalsContact CZ-CG2 3.49Å; A407-V510 HydrophobicContact CB-CB 4.09Å; A407-V510 HydrophobicContact CB-CG1 3.85Å; A506-V510 WeakPolarHBondContact O-CG2 3.24Å; A506-V510 PolarHBondContact O-N 3.35Å; G507-V510 WeakPolarHBondContact O-CB 3.43Å; G507-V510 PolarHBondContact O-N 3.47Å; V510-L512 PolarHBondContact O-N 3.26Å; V510-L512 VanDerWaalsContact O-N 3.07Å; V510-L513 HydrophobicContact CB-CD1 4.5Å; V510-L513 HydrophobicContact CG1-CD1 4.29Å; V510-L513 HydrophobicContact CG2-CD1 4.46Å; V510-L513 VanDerWaalsContact O-CB 3.31Å; V510-L513 WeakPolarHBondContact O-CB 3.47Å; V510-L513 PolarHBondContact O-N 3.26Å
511L94.4Very high90.1Very high68 Ų6857.8 Ų57.836%0.35632%0.321SS..THydrogen-bonded Turntrans-62.7-14.6174.5-63.2174.5000112.7R403 L404 A407 G507 G508 L509 L513R403-L511 PolarHBondContact NE-O 2.83Å; R403-L511 VanDerWaalsContact NE-O 3.12Å; R403-L511 PolarHBondContact NH2-O 3.24Å; L404-L511 HydrophobicContact CD2-CD2 4.34Å; A407-L511 HydrophobicContact CB-CD2 3.46Å; A407-L511 VanDerWaalsContact CB-CD2 3.46Å; A407-L511 HydrophobicContact CB-CG 3.81Å; G507-L511 PolarHBondContact O-N 2.87Å; G508-L511 WeakPolarHBondContact O-CB 3.42Å; G508-L511 PolarHBondContact O-N 2.98Å; L509-L511 PolarHBondContact O-N 3.04Å; L511-L513 VanDerWaalsContact C-N 3.35Å
512L93.5Very high89.1Confident94 Ų9456.9 Ų56.949%0.49231%0.312SS..THydrogen-bonded Turntrans-86.3-6.6175.2-57.5174.9000113.5K345 I349 L509 V510K345-L512 WeakPolarHBondContact CE-O 3.44Å; K345-L512 PolarHBondContact NZ-O 3.37Å; I349-L512 HydrophobicContact CD1-CB 4.06Å; L509-L512 HydrophobicContact CD2-CD1 4.02Å; L509-L512 VanDerWaalsContact O-CB 3.29Å; L509-L512 WeakPolarHBondContact O-CB 3.31Å; L509-L512 PolarHBondContact O-N 3.05Å; V510-L512 PolarHBondContact O-N 3.26Å; V510-L512 VanDerWaalsContact O-N 3.07Å
513L92.6Very high88Confident4 Ų462.3 Ų62.32%0.02134%0.337CS..SBendtrans-81.1152.2176.7-60174.4000111.2H346 I349 L350 R403 F406 V452 L456 V510 L511H346-L513 HydrophobicContact CB-CD2 4.47Å; I349-L513 HydrophobicContact CB-CD2 4.02Å; I349-L513 HydrophobicContact CD1-CD2 3.83Å; I349-L513 HydrophobicContact CD1-CG 4.37Å; I349-L513 HydrophobicContact CG2-CD1 3.88Å; I349-L513 HydrophobicContact CG2-CD2 3.88Å; I349-L513 HydrophobicContact CG2-CG 3.91Å; L350-L513 HydrophobicContact CD2-CD1 4.41Å; R403-L513 WeakPolarHBondContact CD-O 3.34Å; R403-L513 PolarHBondContact NE-O 3.36Å; R403-L513 VanDerWaalsContact NE-O 3.09Å; F406-L513 HydrophobicContact CE1-CD1 4.41Å; V452-L513 HydrophobicContact CG1-CD1 4.29Å; L456-L513 HydrophobicContact CD1-CD1 4.29Å; L456-L513 HydrophobicContact CD1-CD2 4.17Å; V510-L513 HydrophobicContact CB-CD1 4.5Å; V510-L513 HydrophobicContact CG1-CD1 4.29Å; V510-L513 HydrophobicContact CG2-CD1 4.46Å; V510-L513 VanDerWaalsContact O-CB 3.31Å; V510-L513 WeakPolarHBondContact O-CB 3.47Å; V510-L513 PolarHBondContact O-N 3.26Å; L511-L513 VanDerWaalsContact C-N 3.35Å
514P90.1Very high87.1Confident62 Ų6265.2 Ų65.240%0.40336%0.355SS..PPolyproline II helixtrans-73.2158.5172.931.1-34.1000111.2H346 L456H346-P514 WeakPolarHBondContact NE2-CD 3.42Å; H346-P514 WeakPolarHBondContact NE2-CG 3.06Å; L456-P514 HydrophobicContact CD2-CG 3.65Å
515E89.3Confident86.3Confident61 Ų6164.8 Ų64.829%0.28535%0.35SS..PPolyproline II helixtrans-80.8132.6171.9-179.856.9-110.200109.8G401 R402 R403 R517G401-E515 WeakPolarHBondContact CA-OE1 3.24Å; R402-E515 PolarHBondContact N-OE1 2.94Å; R402-E515 PolarHBondContact N-OE2 2.87Å; R403-E515 VanDerWaalsContact CB-OE2 3.3Å; R403-E515 WeakPolarHBondContact CB-OE2 3.11Å; R403-E515 PolarHBondContact N-OE2 3.34Å; R403-E515 VanDerWaalsContact N-OE2 3.16Å; E515-R517 HydrophobicContact CG-CB 4.15Å; E515-R517 WeakPolarHBondContact OE1-CB 3.49Å; E515-R517 PolarHBondContact OE1-N 2.83Å; E515-R517 VanDerWaalsContact OE1-N 3.08Å
516T84.7Confident85.3Confident20 Ų2064.9 Ų64.912%0.12335%0.351CS..  trans-100.1-12-17755.10000112.9R402 E455 L456 G518 V519R402-T516 WeakPolarHBondContact CD-OG1 3.33Å; R402-T516 WeakPolarHBondContact CG-OG1 3.23Å; E455-T516 HydrophobicContact CB-CG2 3.99Å; E455-T516 WeakPolarHBondContact OE2-CB 3.34Å; E455-T516 PolarHBondContact OE2-OG1 2.9Å; L456-T516 HydrophobicContact CD2-CG2 3.86Å; L456-T516 HydrophobicContact CG-CG2 4.16Å; T516-G518 PolarHBondContact O-N 2.93Å; T516-V519 PolarHBondContact O-N 3.19Å
517R82.4Confident84.4Confident107 Ų10766.7 Ų66.740%0.40436%0.361SS..THydrogen-bonded Turntrans-61.3123.5-179.3178.8174.7174.1-156.18.1112.7D398 R399 E515 V519D398-R517 PolarHBondContact O-NE 3.49Å; D398-R517 VanDerWaalsContact O-NE 3.08Å; D398-R517 PolarHBondContact O-NH2 3Å; R399-R517 VanDerWaalsContact O-CZ 3.25Å; R399-R517 PolarHBondContact O-NH1 3.43Å; R399-R517 PolarHBondContact O-NH2 2Å; E515-R517 HydrophobicContact CG-CB 4.15Å; E515-R517 WeakPolarHBondContact OE1-CB 3.49Å; E515-R517 PolarHBondContact OE1-N 2.83Å; E515-R517 VanDerWaalsContact OE1-N 3.08Å; R517-V519 PolarHBondContact O-N 3.13Å
518G70.3Confident83.7Confident84 Ų8467.7 Ų67.787%0.86637%0.366SS*.THydrogen-bonded Turntrans72.96.6175.500000114.1T516T516-G518 PolarHBondContact O-N 2.93Å
519V76.9Confident83.1Confident99 Ų9967.2 Ų67.260%0.636%0.355SS*.PPolyproline II helixtrans-93.5139.4174.3-172.30000108.2T516 R517T516-V519 PolarHBondContact O-N 3.19Å; R517-V519 PolarHBondContact O-N 3.13Å
520R70.1Confident82.3Confident236 Ų23669.7 Ų69.789%0.89136%0.363SS*.PPolyproline II helixtrans-64143.1173.3-69.3-174.8-179.5176.40.4109.3
521L77Confident81.2Confident90 Ų9073.5 Ų73.547%0.47139%0.388SS..PPolyproline II helixtrans-58.7134.3176.1-71.5171000109.5E455 E523E455-L521 HydrophobicContact CB-CD2 4.22Å; E455-L521 HydrophobicContact CG-CD2 4.21Å; L521-E523 PolarHBondContact O-N 3.26Å
522P75.9Confident79.9Confident19 Ų1975.2 Ų75.212%0.12340%0.398CS..PPolyproline II helixtrans-63138.2178.723.5-30000109.9E455 P458 T459 D527 I528E455-P522 WeakPolarHBondContact O-CD 3.28Å; P458-P522 VanDerWaalsContact CA-O 3.25Å; P458-P522 WeakPolarHBondContact CA-O 3.36Å; P458-P522 HydrophobicContact CB-CB 4.38Å; T459-P522 PolarHBondContact N-O 3.16Å; T459-P522 VanDerWaalsContact N-O 3.15Å; T459-P522 PolarHBondContact OG1-O 3.46Å; P522-D527 HydrophobicContact CB-CB 4.1Å; P522-I528 HydrophobicContact CB-CD1 3.97Å; P522-I528 HydrophobicContact CB-CG1 3.79Å; P522-I528 HydrophobicContact CG-CD1 4Å; P522-I528 HydrophobicContact CG-CG1 4.12Å
523E73.9Confident78.2Confident143 Ų14378.6 Ų78.667%0.66840%0.404SS*.  trans-100-35.2176.3-68.3-174.4177.300110.3L521 D527L521-E523 PolarHBondContact O-N 3.26Å; E523-D527 PolarHBondContact N-OD2 3.3Å
524T79.4Confident76.3Confident62 Ų6284.2 Ų84.238%0.3843%0.43SS..SBendtrans-122.9163.5-177.569.60000112.5D526 D527T524-D526 VanDerWaalsContact C-N 3.26Å; T524-D526 PolarHBondContact O-N 3.16Å; T524-D527 PolarHBondContact N-OD2 2.9Å; T524-D527 WeakPolarHBondContact O-CB 3.22Å; T524-D527 PolarHBondContact O-N 2.74Å; T524-D527 PolarHBondContact OG1-N 3.26Å; T524-D527 PolarHBondContact OG1-OD1 2.84Å; T524-D527 PolarHBondContact OG1-OD2 3.1Å; T524-D527 VanDerWaalsContact OG1-OD2 3.04Å
525I80.6Confident74.3Confident26 Ų2688.7 Ų88.713%0.13344%0.443CS..Hα-helixtrans-66.3-33.1173.8-67.4171.1000110.7D336 T340 M343 P458 F460 D527 I528 E529D336-I525 HydrophobicContact CB-CD1 4.01Å; T340-I525 HydrophobicContact CG2-CG2 3.86Å; M343-I525 HydrophobicContact CG-CG2 3.97Å; P458-I525 HydrophobicContact CG-CG1 4.15Å; F460-I525 HydrophobicContact CE1-CD1 4.4Å; F460-I525 HydrophobicContact CE1-CG1 4.01Å; F460-I525 HydrophobicContact CZ-CD1 3.66Å; F460-I525 HydrophobicContact CZ-CG1 3.78Å; I525-D527 PolarHBondContact O-N 2.62Å; I525-I528 PolarHBondContact O-N 2.95Å; I525-E529 HydrophobicContact CG2-CG 4.24Å; I525-E529 PolarHBondContact O-N 3.46Å; I525-E529 VanDerWaalsContact O-N 3.13Å
526D78Confident72Confident97 Ų9793 Ų9352%0.51946%0.463SS..Hα-helixtrans-63.9-29.9179.7-70.5-23.5000112.2T524 I528 E529 F530T524-D526 VanDerWaalsContact C-N 3.26Å; T524-D526 PolarHBondContact O-N 3.16Å; D526-I528 PolarHBondContact O-N 3.31Å; D526-E529 PolarHBondContact O-N 3Å; D526-F530 PolarHBondContact O-N 3.42Å
527D77.3Confident69.8Low39 Ų3998 Ų9821%0.20949%0.489CS..Hα-helixtrans-61-31.6174.3-61.6-33.5000112.3P522 E523 T524 I525 H534P522-D527 HydrophobicContact CB-CB 4.1Å; E523-D527 PolarHBondContact N-OD2 3.3Å; T524-D527 PolarHBondContact N-OD2 2.9Å; T524-D527 WeakPolarHBondContact O-CB 3.22Å; T524-D527 PolarHBondContact O-N 2.74Å; T524-D527 PolarHBondContact OG1-N 3.26Å; T524-D527 PolarHBondContact OG1-OD1 2.84Å; T524-D527 PolarHBondContact OG1-OD2 3.1Å; T524-D527 VanDerWaalsContact OG1-OD2 3.04Å; I525-D527 PolarHBondContact O-N 2.62Å; D527-H534 IonicContact OD1-CD2 3.5Å; D527-H534 IonicContact OD1-NE2 3.85Å
528I82.9Confident67.9Low20 Ų2098.6 Ų98.610%0.10350%0.497CS..Hα-helixtrans-87.2-35-177.4-60.4167.8000110.7N342 M343 L456 P458 P522 I525 D526N342-I528 HydrophobicContact CB-CG2 4.32Å; N342-I528 PolarHBondContact ND2-O 3.17Å; M343-I528 HydrophobicContact CE-CD1 4.39Å; M343-I528 HydrophobicContact CG-CG2 4.28Å; M343-I528 HydrophobicContact SD-CB 4.07Å; M343-I528 HydrophobicContact SD-CD1 3.3Å; M343-I528 WeakPolarHBondContact SD-CD1 3.07Å; M343-I528 HydrophobicContact SD-CG1 4.26Å; M343-I528 HydrophobicContact SD-CG2 3.76Å; L456-I528 VanDerWaalsContact O-CD1 3.28Å; L456-I528 WeakPolarHBondContact O-CD1 3.19Å; P458-I528 HydrophobicContact CB-CD1 4.28Å; P458-I528 HydrophobicContact CG-CD1 4.06Å; P522-I528 HydrophobicContact CB-CD1 3.97Å; P522-I528 HydrophobicContact CB-CG1 3.79Å; P522-I528 HydrophobicContact CG-CD1 4Å; P522-I528 HydrophobicContact CG-CG1 4.12Å; I525-I528 PolarHBondContact O-N 2.95Å; D526-I528 PolarHBondContact O-N 3.31Å
529E83.1Confident66.2Low24 Ų2498.9 Ų98.911%0.11248%0.483CS..Hα-helixtrans-76.7-35.1177.3-64.9-58.2151.100112.3T340 P341 N342 M343 I525 D526 P531T340-E529 WeakPolarHBondContact CB-OE1 3.3Å; T340-E529 HydrophobicContact CG2-CG 4.21Å; T340-E529 PolarHBondContact OG1-OE1 3.31Å; P341-E529 WeakPolarHBondContact CD-OE2 3.34Å; P341-E529 WeakPolarHBondContact CG-OE2 3.4Å; N342-E529 WeakPolarHBondContact CA-OE1 3.37Å; N342-E529 WeakPolarHBondContact CB-OE1 3.22Å; N342-E529 WeakPolarHBondContact CB-OE2 2.96Å; N342-E529 PolarHBondContact N-OE1 2.91Å; N342-E529 PolarHBondContact N-OE2 3.39Å; N342-E529 PolarHBondContact ND2-O 3.3Å; N342-E529 PolarHBondContact ND2-OE2 2.87Å; M343-E529 PolarHBondContact N-OE1 3.47Å; I525-E529 HydrophobicContact CG2-CG 4.24Å; I525-E529 PolarHBondContact O-N 3.46Å; I525-E529 VanDerWaalsContact O-N 3.13Å; D526-E529 PolarHBondContact O-N 3Å; E529-P531 VanDerWaalsContact C-CD 3.44Å; E529-P531 WeakPolarHBondContact O-CD 3.36Å
530F80.9Confident64.1Low108 Ų108102.2 Ų102.247%0.47449%0.49SS..  trans-125.764.3-176.3-54.3-73.9000113.4D526 N532 R533D526-F530 PolarHBondContact O-N 3.42Å; F530-N532 PolarHBondContact O-N 3.05Å; F530-R533 HydrophobicContact CB-CB 4.23Å; F530-R533 HydrophobicContact CB-CG 4.42Å; F530-R533 PolarHBondContact O-N 2.87Å; F530-R533 VanDerWaalsContact O-N 3.08Å
531P71.6Confident62.2Low81 Ų8194.3 Ų94.353%0.52647%0.47SS..THydrogen-bonded Turntrans-62.4-17.6-174.822.8-33000114.7E529E529-P531 VanDerWaalsContact C-CD 3.44Å; E529-P531 WeakPolarHBondContact O-CD 3.36Å
532N67.1Low60.1Low104 Ų10497.4 Ų97.456%0.55648%0.482SS*.THydrogen-bonded Turntrans-88.4-17178.9-68.6-26.3000114.2F530 H534 K535 E536F530-N532 PolarHBondContact O-N 3.05Å; N532-H534 VanDerWaalsContact C-N 3.3Å; N532-H534 PolarHBondContact O-N 2.77Å; N532-K535 PolarHBondContact O-N 2.91Å; N532-K535 VanDerWaalsContact O-N 3.16Å; N532-E536 PolarHBondContact O-N 2.9Å
533R59.2Low58Low165 Ų165103.9 Ų103.962%0.62351%0.511SS*.Hα-helixtrans-63.2-34.1-178.4-111179.7171.6-179.4-3112.9F530F530-R533 HydrophobicContact CB-CB 4.23Å; F530-R533 HydrophobicContact CB-CG 4.42Å; F530-R533 PolarHBondContact O-N 2.87Å; F530-R533 VanDerWaalsContact O-N 3.08Å
534H51Low56Low121 Ų121103.4 Ų103.456%0.5651%0.512SS*.Hα-helixtrans-81.9-20.1176.9-86.3-75.2000114.2D527 N532 E536D527-H534 IonicContact OD1-CD2 3.5Å; D527-H534 IonicContact OD1-NE2 3.85Å; N532-H534 VanDerWaalsContact C-N 3.3Å; N532-H534 PolarHBondContact O-N 2.77Å; H534-E536 VanDerWaalsContact C-N 3.35Å
535K49.1Very low53.9Low157 Ų157105.6 Ų105.668%0.68353%0.526SS*.Hα-helixtrans-71.1-31.8171.9-75.5-179.2177.9174.10111.7N532 H538N532-K535 PolarHBondContact O-N 2.91Å; N532-K535 VanDerWaalsContact O-N 3.16Å; K535-H538 PolarHBondContact O-N 3.33Å
536E40.9Very low51.6Low151 Ų151111.1 Ų111.171%0.70656%0.555SS**Hα-helixtrans-78.7-20178.8-74.3-177.2163.600114.5N532 H534 H538 P539N532-E536 PolarHBondContact O-N 2.9Å; H534-E536 VanDerWaalsContact C-N 3.35Å; E536-H538 PolarHBondContact O-N 3.44Å; E536-P539 WeakPolarHBondContact O-CD 3.45Å
537N37.4Very low49.6Very low126 Ų126113.1 Ų113.167%0.67457%0.565SS**THydrogen-bonded Turntrans-77.21.3169.5-80.7-18.1000113.2
538H43Very low47.6Very low119 Ų119118.3 Ų118.355%0.55159%0.592SS**  trans-130.661.3177.4-109.7-54.8000114.9K535 E536 S541K535-H538 PolarHBondContact O-N 3.33Å; E536-H538 PolarHBondContact O-N 3.44Å; H538-S541 PolarHBondContact CE1-OG 3.31Å; H538-S541 PolarHBondContact ND1-OG 3.42Å
539P35.8Very low45.3Very low90 Ų90122.6 Ų122.658%0.58462%0.622SS**SBendtrans-106.8124.3143.432.9-26.2000109.2E536E536-P539 WeakPolarHBondContact O-CD 3.45Å
540K31.7Very low43Very low169 Ų169127.9 Ų127.974%0.73566%0.656SS**SBendtrans92-13.1160.6-55.3176.9176.2179.60121.5Q542 Q543 L544K540-Q542 VanDerWaalsContact C-N 3.32Å; K540-Q542 PolarHBondContact O-N 3.46Å; K540-Q543 PolarHBondContact O-N 3.04Å; K540-L544 PolarHBondContact O-N 3.25Å
541S30.6Very low40.5Very low69 Ų69130.4 Ų130.448%0.48367%0.674SS.*Hα-helixtrans-71.8-19.8-17953.70000115.1H538 T545H538-S541 PolarHBondContact CE1-OG 3.31Å; H538-S541 PolarHBondContact ND1-OG 3.42Å; S541-T545 PolarHBondContact O-OG1 2.79Å
542Q33.5Very low38.7Very low155 Ų155134.7 Ų134.772%0.72469%0.689SS**Hα-helixtrans-92.1-8.2178.3-117.2168.6-8.600114.5K540K540-Q542 VanDerWaalsContact C-N 3.32Å; K540-Q542 PolarHBondContact O-N 3.46Å
543Q31Very low37Very low155 Ų155136 Ų13672%0.72470%0.701SS**Hα-helixtrans-99.2-20.1173-86.1-179.4-23.600113.1K540K540-Q543 PolarHBondContact O-N 3.04Å
544L32.8Very low35.5Very low133 Ų133133.6 Ų133.670%0.69671%0.705SS**Hα-helixtrans-82.1-22.9-178.4-138.580.2000113.7K540 N546K540-L544 PolarHBondContact O-N 3.25Å; L544-N546 VanDerWaalsContact C-N 3.3Å; L544-N546 PolarHBondContact O-N 3.36Å
545T33.5Very low34.5Very low109 Ų109135.1 Ų135.167%0.66972%0.717SS**THydrogen-bonded Turntrans-78.8-11.5179.3-13.20000113.8S541S541-T545 PolarHBondContact O-OG1 2.79Å
546N34.2Very low33.5Very low141 Ų141137.7 Ų137.775%0.75473%0.729SS**THydrogen-bonded Turntrans-99.48.9180-74.9-9.5000113.8L544L544-N546 VanDerWaalsContact C-N 3.3Å; L544-N546 PolarHBondContact O-N 3.36Å
547L35.9Very low33.2Very low139 Ų139139.4 Ų139.473%0.72874%0.737SS**SBendtrans-118.314.6-178.7-77.2172.5000114.8
548L35.3Very low32.8Very low148 Ų148137.9 Ų137.978%0.77574%0.741SS**  trans-108.7106.8167.9-78.3160.5000109.4T550L548-T550 PolarHBondContact O-N 3.29Å
549P34.3Very low32.1Very low111 Ų111138.5 Ų138.572%0.72175%0.753SS**  trans-68118.4165.7-723000108.1D551P549-D551 PolarHBondContact O-N 3.14Å; P549-D551 VanDerWaalsContact O-N 3.15Å
550T34.4Very low32Very low134 Ų134141.6 Ų141.682%0.82276%0.763SS**  trans-68.794.2160.138.40000109L548 M552L548-T550 PolarHBondContact O-N 3.29Å; T550-M552 PolarHBondContact O-N 3.03Å
551D28.9Very low32.1Very low162 Ų162143.6 Ų143.687%0.86679%0.789SS**  trans-81.3102.9158.5-89.3-22.5000108.7P549P549-D551 PolarHBondContact O-N 3.14Å; P549-D551 VanDerWaalsContact O-N 3.15Å
552M33.2Very low32.2Very low170 Ų170147.3 Ų147.384%0.83781%0.805SS**  trans-120.2121.1157.3-97.5-156.9-76.200108.1T550T550-M552 PolarHBondContact O-N 3.03Å
553T30.2Very low32.1Very low131 Ų131146.9 Ų146.980%0.80481%0.809SS**  trans163.2135.3150.136.80000105.8
554T29.7Very low32.2Very low116 Ų116146.4 Ų146.471%0.71281%0.814SS**  cis-175146.36.910.60000106.3
555N28.8Very low32.1Very low152 Ų152147.2 Ų147.281%0.81382%0.82SS**  trans31.7123.8149.3-69.7-7.7000121.4
556K29.1Very low32Very low212 Ų212149.6 Ų149.692%0.92283%0.83SS**  -155.8128.1123.5-108.1172-173.9-177.60111.1
557E32.8Very low31.9Very low187 Ų187150.2 Ų150.287%0.87484%0.835SS**  trans-67.6173.7171.2-67.1172134.100112.8
558A29.8Very low31.6Very low93 Ų93151 Ų15177%0.76984%0.843SS**  trans92130.8156.700000114.9
559T29.2Very low31.3Very low132 Ų132151.2 Ų151.281%0.8185%0.848SS**  cis-163.9164.22.4-43.60000107.7
560I33.3Very low31.1Very low155 Ų155154.6 Ų154.680%0.79586%0.858SS**  trans-58.6151.8167.4-63.6158.2000112.4
561V33.3Very low30.8Very low211 Ų211156.5 Ų156.5100%1.27986%0.862SS**  trans92.30176.6-164.70000115.8

Retrieved 561 of 561 residues in 3556 ms (Link to these results)

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