A0A060WID5_ONCMY Loading...

Monocarboxylate transporter 2

Proton-coupled monocarboxylate symporter. Catalyzes the rapid transport across the plasma membrane of monocarboxylates such as L-lactate, pyruvate and ketone bodies, acetoacetate, beta-hydroxybutyrate and acetate. Dimerization is functionally required and both subunits work cooperatively in transporting substrate.

AlphaFold DB , UniProt , Accession A0A060WID5, Species ONCMY (Oncorhynchus mykiss, Rainbow trout), Gene n/a, Length 481 aa.

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	31.2	Very low	39.4	Very low	232 Å²	232	108.5 Å²	108.5	100%	1.143	74%	0.737	S	S	*	*				0	128.6	0	-67.1	177.6	-157.9	0	0	108.6
2	P	28.1	Very low	41.6	Very low	119 Å²	119	109.5 Å²	109.5	77%	0.773	74%	0.737	S	S	*	*	P	Polyproline II helix	trans	-60.1	143.6	167.1	27.1	-31.1	0	0	0	108.7
3	P	33	Very low	44.1	Very low	98 Å²	98	103.5 Å²	103.5	64%	0.636	70%	0.696	S	S	*	*	P	Polyproline II helix	trans	-59.6	145.7	175	25.2	-31.5	0	0	0	109.3	A5	P3-A5 PolarHBondContact O-N 3.49Å
4	P	30.6	Very low	46.1	Very low	125 Å²	125	100.8 Å²	100.8	81%	0.812	68%	0.676	S	S	*	*	P	Polyproline II helix	trans	-54.4	131.8	-179.2	21	-30.6	0	0	0	109.4	A6	P4-A6 PolarHBondContact O-N 3.39Å; P4-A6 VanDerWaalsContact O-N 3.16Å
5	A	37.4	Very low	48.2	Very low	92 Å²	92	96.3 Å²	96.3	76%	0.76	64%	0.643	S	S	*	*			trans	-45.1	125.9	171.7	0	0	0	0	0	108	P3 G7	P3-A5 PolarHBondContact O-N 3.49Å; A5-G7 PolarHBondContact O-N 2.79Å
6	A	41.8	Very low	50.2	Low	90 Å²	90	91.3 Å²	91.3	74%	0.744	61%	0.613	S	S	*	*			trans	-43.3	119.1	178.6	0	0	0	0	0	108.4	P4	P4-A6 PolarHBondContact O-N 3.39Å; P4-A6 VanDerWaalsContact O-N 3.16Å
7	G	32.8	Very low	52.5	Low	58 Å²	58	89.8 Å²	89.8	60%	0.598	62%	0.617	S	S	*	*	P	Polyproline II helix	trans	-51.4	152.8	-177.6	0	0	0	0	0	110.7	A5	A5-G7 PolarHBondContact O-N 2.79Å
8	P	36.1	Very low	54.5	Low	120 Å²	120	92.1 Å²	92.1	78%	0.779	61%	0.611	S	S	*	*	P	Polyproline II helix	trans	-52.6	139.1	-179.6	21.5	-31.1	0	0	0	109.7	A10	P8-A10 PolarHBondContact O-N 3.38Å
9	P	49.5	Very low	56.3	Low	80 Å²	80	87.3 Å²	87.3	52%	0.519	58%	0.578	S	S	.	*	P	Polyproline II helix	trans	-53.8	135.8	178.4	21.3	-31.2	0	0	0	109.2	V11	P9-V11 CarbonylContact O-C 3.18Å; P9-V11 PolarHBondContact O-N 3.26Å
10	A	51.8	Low	58.1	Low	112 Å²	112	88.2 Å²	88.2	93%	0.926	57%	0.57	S	S	*	*	S	Bend	trans	-54.5	-15.4	-175.1	0	0	0	0	0	114.4	P8	P8-A10 PolarHBondContact O-N 3.38Å
11	V	61.3	Low	59.8	Low	68 Å²	68	85.3 Å²	85.3	41%	0.412	55%	0.553	S	S	.	*	S	Bend	trans	-131.3	126.8	166.7	-178.4	0	0	0	0	107.9	P9 P13	P9-V11 CarbonylContact O-C 3.18Å; P9-V11 PolarHBondContact O-N 3.26Å; V11-P13 WeakPolarHBondContact O-CD 3.5Å
12	T	65.9	Low	62.7	Low	120 Å²	120	74.2 Å²	74.2	74%	0.736	50%	0.499	S	S	*	.			trans	-63	122.6	174.3	47.9	0	0	0	0	109.7
13	P	73.4	Confident	65.9	Low	32 Å²	32	68.8 Å²	68.8	21%	0.208	46%	0.463	C	S	.	.			trans	-62.7	131.5	-179.7	19.9	-26.8	0	0	0	110	V11 D15 Y140	V11-P13 WeakPolarHBondContact O-CD 3.5Å; P13-D15 VanDerWaalsContact C-N 3.26Å; P13-D15 PolarHBondContact O-N 3.14Å; P13-Y140 HydrophobicContact CG-CG 4.38Å
14	P	73.3	Confident	68.8	Low	65 Å²	65	69 Å²	69	42%	0.422	46%	0.458	S	S	.	.			trans	-70.3	-17.8	-173.1	25.3	-33.7	0	0	0	114	G16 Y138 L198	P14-G16 PolarHBondContact O-N 3.16Å; P14-Y138 WeakPolarHBondContact CD-O 3.42Å; P14-Y138 HydrophobicContact CG-CD1 3.76Å; P14-Y138 HydrophobicContact CG-CE1 4.14Å; P14-L198 HydrophobicContact CG-CD1 4.13Å; P14-L198 HydrophobicContact CG-CD2 4.17Å
15	D	76.4	Confident	71.8	Confident	33 Å²	33	63 Å²	63	18%	0.176	42%	0.42	C	S	.	.			trans	50.2	28.3	176.6	-90.2	-38.3	0	0	0	114.3	P13 Y138 F139 Y140 K141 K142	P13-D15 VanDerWaalsContact C-N 3.26Å; P13-D15 PolarHBondContact O-N 3.14Å; D15-Y138 PolarHBondContact N-O 3.25Å; D15-Y138 VanDerWaalsContact N-O 3.1Å; D15-F139 VanDerWaalsContact OD1-CA 3.24Å; D15-F139 WeakPolarHBondContact OD1-CA 3.37Å; D15-Y140 PolarHBondContact OD1-N 3.36Å; D15-K141 PolarHBondContact OD1-N 3.42Å; D15-K141 VanDerWaalsContact OD1-N 3.15Å; D15-K141 WeakPolarHBondContact OD2-CB 3.39Å; D15-K141 PolarHBondContact OD2-N 3.46Å; D15-K142 PolarHBondContact OD1-N 2.83Å
16	G	81.4	Confident	74.5	Confident	16 Å²	16	58.7 Å²	58.7	17%	0.165	38%	0.384	C	S	.	.	S	Bend	trans	171.6	-166.7	-175.6	0	0	0	0	0	114.3	P14 W18 G19	P14-G16 PolarHBondContact O-N 3.16Å; G16-W18 PolarHBondContact O-N 3.14Å; G16-G19 PolarHBondContact O-N 3.1Å
17	G	88.3	Confident	77	Confident	66 Å²	66	56.4 Å²	56.4	68%	0.68	36%	0.357	S	S	*	.	T	Hydrogen-bonded Turn	trans	59.6	-123.9	178.4	0	0	0	0	0	113	G19 W20	G17-G19 PolarHBondContact O-N 3.38Å; G17-W20 PolarHBondContact O-N 3.41Å; G17-W20 VanDerWaalsContact O-N 3.08Å
18	W	89.6	Confident	80	Confident	132 Å²	132	55.8 Å²	55.8	50%	0.5	34%	0.339	S	S	.	.	H	α-helix	trans	-59.8	-17.4	177.5	-160.3	-92.4	0	0	0	113.5	G16 W20 A21 V22 Y138 L194	G16-W18 PolarHBondContact O-N 3.14Å; W18-W20 PolarHBondContact O-N 3.08Å; W18-A21 HydrophobicContact CD2-CB 4.18Å; W18-A21 HydrophobicContact CG-CB 4.43Å; W18-A21 WeakPolarHBondContact O-CB 3.45Å; W18-A21 PolarHBondContact O-N 3Å; W18-A21 VanDerWaalsContact O-N 3.09Å; W18-V22 PolarHBondContact O-N 3.43Å; W18-Y138 HydrophobicContact CB-CE1 4.34Å; W18-L194 HydrophobicContact CZ2-CD2 4.36Å; W18-L194 PolarHBondContact NE1-O 3.06Å
19	G	88.1	Confident	82.8	Confident	0 Å²	0	50 Å²	50	0%	0	30%	0.302	C	S	.	.	H	α-helix	trans	-54.8	-35.4	171.6	0	0	0	0	0	112.8	G16 G17 V22 V23 F139	G16-G19 PolarHBondContact O-N 3.1Å; G17-G19 PolarHBondContact O-N 3.38Å; G19-V22 WeakPolarHBondContact O-CB 3.45Å; G19-V22 PolarHBondContact O-N 2.84Å; G19-V23 WeakPolarHBondContact O-CG2 3.44Å; G19-V23 PolarHBondContact O-N 3.49Å; G19-F139 VanDerWaalsContact C-CZ 3.46Å; G19-F139 WeakPolarHBondContact O-CE2 3.4Å
20	W	92.9	Very high	84.8	Confident	106 Å²	106	46.2 Å²	46.2	40%	0.402	28%	0.278	S	S	.	.	H	α-helix	trans	-72	-32.1	177.4	-65.8	113.2	0	0	0	113.2	G17 W18 V22 V23 L24 F139 K142 I145 I149	G17-W20 PolarHBondContact O-N 3.41Å; G17-W20 VanDerWaalsContact O-N 3.08Å; W18-W20 PolarHBondContact O-N 3.08Å; W20-V22 VanDerWaalsContact C-N 3.31Å; W20-V23 HydrophobicContact CE3-CB 4.43Å; W20-V23 HydrophobicContact CE3-CG2 4.24Å; W20-V23 PolarHBondContact O-N 3.14Å; W20-L24 PolarHBondContact O-N 3.43Å; W20-F139 HydrophobicContact CD2-CZ 4.23Å; W20-F139 HydrophobicContact CE3-CZ 4.45Å; W20-F139 HydrophobicContact CZ2-CE1 4.44Å; W20-K142 HydrophobicContact CZ2-CD 4.37Å; W20-I145 HydrophobicContact CH2-CG2 4.38Å; W20-I149 HydrophobicContact CZ3-CD1 3.83Å
21	A	93.4	Very high	86.8	Confident	27 Å²	27	40.9 Å²	40.9	22%	0.223	23%	0.233	C	C	.	.	H	α-helix	trans	-66.2	-36.9	170.3	0	0	0	0	0	111.3	W18 L24 G25	W18-A21 HydrophobicContact CD2-CB 4.18Å; W18-A21 HydrophobicContact CG-CB 4.43Å; W18-A21 WeakPolarHBondContact O-CB 3.45Å; W18-A21 PolarHBondContact O-N 3Å; W18-A21 VanDerWaalsContact O-N 3.09Å; A21-L24 PolarHBondContact O-N 3.4Å; A21-G25 PolarHBondContact O-N 3.01Å
22	V	92.5	Very high	88.4	Confident	0 Å²	0	38.1 Å²	38.1	0%	0	22%	0.216	C	C	.	.	H	α-helix	trans	-63.6	-41.6	171.4	164.7	0	0	0	0	111.3	W18 G19 W20 L24 G25 S26 M134 Y138 M195	W18-V22 PolarHBondContact O-N 3.43Å; G19-V22 WeakPolarHBondContact O-CB 3.45Å; G19-V22 PolarHBondContact O-N 2.84Å; W20-V22 VanDerWaalsContact C-N 3.31Å; V22-L24 VanDerWaalsContact C-N 3.32Å; V22-L24 PolarHBondContact O-N 2.97Å; V22-G25 PolarHBondContact O-N 2.86Å; V22-S26 WeakPolarHBondContact O-CB 3.2Å; V22-S26 PolarHBondContact O-N 3.41Å; V22-S26 PolarHBondContact O-OG 2.63Å; V22-M134 HydrophobicContact CG1-CB 3.98Å; V22-Y138 HydrophobicContact CB-CD2 4.47Å; V22-Y138 HydrophobicContact CG1-CD2 4.19Å; V22-Y138 HydrophobicContact CG1-CG 4.49Å; V22-Y138 HydrophobicContact CG2-CD2 4.09Å; V22-Y138 HydrophobicContact CG2-CE1 4.3Å; V22-Y138 HydrophobicContact CG2-CE2 3.82Å; V22-Y138 HydrophobicContact CG2-CG 4.45Å; V22-M195 HydrophobicContact CB-SD 4.28Å; V22-M195 HydrophobicContact CG1-CE 4.38Å; V22-M195 HydrophobicContact CG1-SD 3.68Å; V22-M195 HydrophobicContact CG2-SD 4.19Å
23	V	93.4	Very high	89.7	Confident	4 Å²	4	32.4 Å²	32.4	2%	0.024	18%	0.181	C	C	.	.	H	α-helix	trans	-60.4	-42.1	173.9	175.6	0	0	0	0	111.1	G19 W20 S26 F27 F139 A146 I149	G19-V23 WeakPolarHBondContact O-CG2 3.44Å; G19-V23 PolarHBondContact O-N 3.49Å; W20-V23 HydrophobicContact CE3-CB 4.43Å; W20-V23 HydrophobicContact CE3-CG2 4.24Å; W20-V23 PolarHBondContact O-N 3.14Å; V23-S26 PolarHBondContact O-N 3.39Å; V23-F27 WeakPolarHBondContact O-CB 3.22Å; V23-F27 PolarHBondContact O-N 3.04Å; V23-F139 HydrophobicContact CG2-CD2 4.4Å; V23-F139 HydrophobicContact CG2-CE2 3.56Å; V23-F139 HydrophobicContact CG2-CZ 4.06Å; V23-A146 HydrophobicContact CG2-CB 3.78Å; V23-I149 HydrophobicContact CG1-CB 3.99Å; V23-I149 HydrophobicContact CG1-CG2 3.63Å
24	L	94.9	Very high	90.6	Very high	103 Å²	103	32.6 Å²	32.6	54%	0.539	18%	0.178	S	C	.	.	H	α-helix	trans	-62.8	-44.3	176.1	-178.5	65.4	0	0	0	111.9	W20 A21 V22 S26 F27 I28	W20-L24 PolarHBondContact O-N 3.43Å; A21-L24 PolarHBondContact O-N 3.4Å; V22-L24 VanDerWaalsContact C-N 3.32Å; V22-L24 PolarHBondContact O-N 2.97Å; L24-S26 VanDerWaalsContact C-N 3.35Å; L24-S26 PolarHBondContact O-N 2.99Å; L24-F27 WeakPolarHBondContact O-CB 3.13Å; L24-F27 PolarHBondContact O-N 2.9Å; L24-I28 WeakPolarHBondContact O-CG1 3.39Å; L24-I28 PolarHBondContact O-N 3.36Å
25	G	94.3	Very high	91.5	Very high	0 Å²	0	29.5 Å²	29.5	0%	0	16%	0.158	C	C	.	.	H	α-helix	trans	-59.7	-45.9	173.4	0	0	0	0	0	111.8	A21 V22 F27 I28 S29	A21-G25 PolarHBondContact O-N 3.01Å; V22-G25 PolarHBondContact O-N 2.86Å; G25-F27 VanDerWaalsContact C-N 3.32Å; G25-F27 PolarHBondContact O-N 2.78Å; G25-I28 PolarHBondContact O-N 2.78Å; G25-S29 PolarHBondContact O-N 2.87Å; G25-S29 PolarHBondContact O-OG 3.04Å
26	S	93.4	Very high	92.3	Very high	0 Å²	0	28 Å²	28	0%	0	15%	0.15	C	C	.	.	H	α-helix	trans	-65	-35.3	177.2	-66.6	0	0	0	0	112.5	V22 V23 L24 I28 S29 I30 A131 M195	V22-S26 WeakPolarHBondContact O-CB 3.2Å; V22-S26 PolarHBondContact O-N 3.41Å; V22-S26 PolarHBondContact O-OG 2.63Å; V23-S26 PolarHBondContact O-N 3.39Å; L24-S26 VanDerWaalsContact C-N 3.35Å; L24-S26 PolarHBondContact O-N 2.99Å; S26-I28 VanDerWaalsContact C-N 3.32Å; S26-I28 PolarHBondContact O-N 3.45Å; S26-S29 PolarHBondContact O-N 3.39Å; S26-I30 WeakPolarHBondContact O-CB 3.5Å; S26-I30 WeakPolarHBondContact O-CG1 3.21Å; S26-I30 PolarHBondContact O-N 3.13Å; S26-A131 PolarHBondContact OG-O 2.82Å; S26-A131 VanDerWaalsContact OG-O 3.12Å; S26-M195 WeakPolarHBondContact OG-CE 3.3Å
27	F	95	Very high	92.9	Very high	43 Å²	43	27.5 Å²	27.5	19%	0.189	14%	0.143	C	C	.	.	H	α-helix	trans	-58.4	-44.9	174.7	-178.9	-85.5	0	0	0	111.2	V23 L24 G25 G31 I149 G153 V156 F157	V23-F27 WeakPolarHBondContact O-CB 3.22Å; V23-F27 PolarHBondContact O-N 3.04Å; L24-F27 WeakPolarHBondContact O-CB 3.13Å; L24-F27 PolarHBondContact O-N 2.9Å; G25-F27 VanDerWaalsContact C-N 3.32Å; G25-F27 PolarHBondContact O-N 2.78Å; F27-G31 WeakPolarHBondContact O-CA 3.09Å; F27-G31 PolarHBondContact O-N 3.49Å; F27-I149 HydrophobicContact CD2-CG2 4.36Å; F27-I149 WeakPolarHBondContact CD2-O 2.97Å; F27-G153 VanDerWaalsContact CE2-N 3.29Å; F27-G153 VanDerWaalsContact CZ-CA 3.44Å; F27-V156 HydrophobicContact CZ-CB 4.04Å; F27-V156 HydrophobicContact CZ-CG1 4.17Å; F27-V156 HydrophobicContact CZ-CG2 4.1Å; F27-F157 AromaticContact CD1-CE2 3.87Å; F27-F157 HydrophobicContact CD1-CE2 3.87Å; F27-F157 HydrophobicContact CE1-CD2 4.15Å; F27-F157 AromaticContact CE1-CE2 3.67Å; F27-F157 HydrophobicContact CE1-CE2 3.67Å
28	I	95.3	Very high	93	Very high	44 Å²	44	24.9 Å²	24.9	23%	0.226	11%	0.113	C	C	.	.	H	α-helix	trans	-67.5	-50	178	-63.3	167.5	0	0	0	110.5	L24 G25 S26 G31 F32 F157 A191	L24-I28 WeakPolarHBondContact O-CG1 3.39Å; L24-I28 PolarHBondContact O-N 3.36Å; G25-I28 PolarHBondContact O-N 2.78Å; S26-I28 VanDerWaalsContact C-N 3.32Å; S26-I28 PolarHBondContact O-N 3.45Å; I28-G31 PolarHBondContact O-N 2.95Å; I28-F32 HydrophobicContact CG2-CD2 3.72Å; I28-F32 HydrophobicContact CG2-CE2 3.65Å; I28-F32 WeakPolarHBondContact O-CD2 3.24Å; I28-F32 PolarHBondContact O-N 3.07Å; I28-F157 HydrophobicContact CB-CZ 4.31Å; I28-F157 HydrophobicContact CG1-CZ 4.21Å; I28-F157 HydrophobicContact CG2-CZ 4.16Å; I28-A191 HydrophobicContact CB-CB 4.06Å; I28-A191 HydrophobicContact CG2-CB 4.06Å
29	S	94.2	Very high	93.2	Very high	0 Å²	0	18.6 Å²	18.6	0%	0	9%	0.089	C	C	.	.	H	α-helix	trans	-63.4	-47.3	-178.1	-66.7	0	0	0	0	112.6	G25 S26 G31 S33 M89	G25-S29 PolarHBondContact O-N 2.87Å; G25-S29 PolarHBondContact O-OG 3.04Å; S26-S29 PolarHBondContact O-N 3.39Å; S29-G31 VanDerWaalsContact C-N 3.31Å; S29-S33 WeakPolarHBondContact O-CB 3.47Å; S29-S33 PolarHBondContact O-N 3.1Å; S29-S33 PolarHBondContact O-OG 2.81Å; S29-S33 VanDerWaalsContact O-OG 3.07Å; S29-M89 VanDerWaalsContact OG-CE 3.29Å; S29-M89 WeakPolarHBondContact OG-CE 3.16Å
30	I	92.4	Very high	93.3	Very high	0 Å²	0	18.7 Å²	18.7	0%	0	9%	0.089	C	C	.	.	H	α-helix	trans	-66.2	-38.5	176.6	-64.1	176.6	0	0	0	110.4	S26 S33 Y34 L128 A131 L132 A150 M151	S26-I30 WeakPolarHBondContact O-CB 3.5Å; S26-I30 WeakPolarHBondContact O-CG1 3.21Å; S26-I30 PolarHBondContact O-N 3.13Å; I30-S33 PolarHBondContact O-N 3.08Å; I30-Y34 HydrophobicContact CG2-CD2 3.76Å; I30-Y34 HydrophobicContact CG2-CE2 4.13Å; I30-Y34 PolarHBondContact O-N 3.06Å; I30-Y34 VanDerWaalsContact O-N 3.09Å; I30-L128 HydrophobicContact CB-CD1 4.47Å; I30-L128 HydrophobicContact CG1-CD1 3.93Å; I30-L128 HydrophobicContact CG2-CD1 4.37Å; I30-A131 HydrophobicContact CG1-CB 4.29Å; I30-L132 HydrophobicContact CD1-CD2 3.86Å; I30-L132 HydrophobicContact CD1-CG 4.37Å; I30-A150 HydrophobicContact CD1-CB 3.82Å; I30-M151 HydrophobicContact CD1-SD 4.36Å; I30-M151 HydrophobicContact CG2-SD 3.9Å
31	G	93.9	Very high	93.3	Very high	0 Å²	0	13.7 Å²	13.7	0%	0	7%	0.071	C	C	.	.	H	α-helix	trans	-52	-59.9	173.6	0	0	0	0	0	111.7	F27 I28 S29 A35	F27-G31 WeakPolarHBondContact O-CA 3.09Å; F27-G31 PolarHBondContact O-N 3.49Å; I28-G31 PolarHBondContact O-N 2.95Å; S29-G31 VanDerWaalsContact C-N 3.31Å; G31-A35 WeakPolarHBondContact O-CB 3.47Å; G31-A35 PolarHBondContact O-N 3.34Å
32	F	94.4	Very high	93.2	Very high	10 Å²	10	12.5 Å²	12.5	4%	0.044	6%	0.061	C	C	.	.	H	α-helix	trans	-61.9	-46.8	177.7	-78.4	-62.2	0	0	0	112.9	I28 Y34 F36 F157 L161 I184 L185 C188	I28-F32 HydrophobicContact CG2-CD2 3.72Å; I28-F32 HydrophobicContact CG2-CE2 3.65Å; I28-F32 WeakPolarHBondContact O-CD2 3.24Å; I28-F32 PolarHBondContact O-N 3.07Å; F32-Y34 PolarHBondContact O-N 2.88Å; F32-F36 WeakPolarHBondContact O-CB 3.46Å; F32-F36 PolarHBondContact O-N 2.94Å; F32-F157 AromaticContact CD1-CD1 3.95Å; F32-F157 HydrophobicContact CD1-CD1 3.95Å; F32-F157 HydrophobicContact CD1-CE1 4.15Å; F32-F157 HydrophobicContact CD2-CD1 4.25Å; F32-F157 AromaticContact CD2-CE1 3.76Å; F32-F157 HydrophobicContact CD2-CE1 3.76Å; F32-F157 AromaticContact CE1-CD1 3.87Å; F32-F157 HydrophobicContact CE1-CD1 3.87Å; F32-F157 AromaticContact CE1-CE1 3.82Å; F32-F157 HydrophobicContact CE1-CE1 3.82Å; F32-F157 HydrophobicContact CE2-CD1 4.21Å; F32-F157 AromaticContact CE2-CE1 3.44Å; F32-F157 HydrophobicContact CE2-CE1 3.44Å; F32-F157 VanDerWaalsContact CE2-CE1 3.44Å; F32-F157 HydrophobicContact CE2-CZ 4.24Å; F32-F157 HydrophobicContact CG-CD1 4.14Å; F32-F157 HydrophobicContact CG-CE1 4.11Å; F32-F157 HydrophobicContact CZ-CD1 4.01Å; F32-F157 AromaticContact CZ-CE1 3.46Å; F32-F157 HydrophobicContact CZ-CE1 3.46Å; F32-F157 VanDerWaalsContact CZ-CE1 3.46Å; F32-L161 HydrophobicContact CD1-CD1 4.21Å; F32-L161 HydrophobicContact CE1-CD1 4.22Å; F32-I184 HydrophobicContact CE1-CG2 3.58Å; F32-I184 HydrophobicContact CZ-CG2 3.39Å; F32-L185 HydrophobicContact CB-CD2 3.97Å; F32-L185 HydrophobicContact CD1-CD2 3.86Å; F32-L185 HydrophobicContact CG-CD2 3.96Å; F32-C188 WeakPolarHBondContact CD2-SG 3.49Å
33	S	93.4	Very high	93.2	Very high	0 Å²	0	12.5 Å²	12.5	0%	0	6%	0.061	C	C	.	.	H	α-helix	trans	-58.1	-43.7	-176.7	-67.1	0	0	0	0	113.1	S29 I30 P37 L124	S29-S33 WeakPolarHBondContact O-CB 3.47Å; S29-S33 PolarHBondContact O-N 3.1Å; S29-S33 PolarHBondContact O-OG 2.81Å; S29-S33 VanDerWaalsContact O-OG 3.07Å; I30-S33 PolarHBondContact O-N 3.08Å; S33-P37 VanDerWaalsContact O-CD 3.23Å; S33-P37 WeakPolarHBondContact O-CD 3.38Å; S33-L124 PolarHBondContact OG-O 3.28Å
34	Y	91.2	Very high	92.9	Very high	36 Å²	36	12.8 Å²	12.8	14%	0.141	6%	0.062	C	C	.	.	H	α-helix	trans	-89.9	-30.2	-179.7	-78.4	-65.6	0	0	0	114.9	I30 F32 M69 Y70 L128 M151 S154	I30-Y34 HydrophobicContact CG2-CD2 3.76Å; I30-Y34 HydrophobicContact CG2-CE2 4.13Å; I30-Y34 PolarHBondContact O-N 3.06Å; I30-Y34 VanDerWaalsContact O-N 3.09Å; F32-Y34 PolarHBondContact O-N 2.88Å; Y34-M69 HydrophobicContact CD1-CE 3.83Å; Y34-M69 HydrophobicContact CE1-CE 3.77Å; Y34-Y70 HydrophobicContact CE1-CE1 4.24Å; Y34-L128 HydrophobicContact CD2-CD1 4.24Å; Y34-L128 HydrophobicContact CE2-CD1 3.64Å; Y34-L128 HydrophobicContact CE2-CD2 4.03Å; Y34-M151 HydrophobicContact CE2-CE 4.36Å; Y34-M151 HydrophobicContact CE2-SD 4.48Å; Y34-S154 VanDerWaalsContact CB-OG 3.24Å; Y34-S154 WeakPolarHBondContact CB-OG 3.46Å
35	A	93.6	Very high	92.6	Very high	0 Å²	0	9.2 Å²	9.2	0%	0	4%	0.042	C	C	.	.	H	α-helix	trans	-78.3	-38.8	-178.9	0	0	0	0	0	112.1	G31 K38 A39 F157 L158 L161	G31-A35 WeakPolarHBondContact O-CB 3.47Å; G31-A35 PolarHBondContact O-N 3.34Å; A35-K38 PolarHBondContact O-N 3.13Å; A35-K38 VanDerWaalsContact O-N 3.08Å; A35-A39 WeakPolarHBondContact O-CB 3.49Å; A35-A39 PolarHBondContact O-N 2.94Å; A35-F157 HydrophobicContact CB-CB 3.71Å; A35-L158 HydrophobicContact CB-CB 3.87Å; A35-L161 HydrophobicContact CB-CD1 4.23Å
36	F	93.4	Very high	92.3	Very high	2 Å²	2	9.9 Å²	9.9	1%	0.009	5%	0.045	C	C	.	.	H	α-helix	trans	-60.5	-44.5	-170.4	-166.3	-92.3	0	0	0	113.8	F32 K38 A39 I40 M65 L100 L124 L181 L185	F32-F36 WeakPolarHBondContact O-CB 3.46Å; F32-F36 PolarHBondContact O-N 2.94Å; F36-K38 PolarHBondContact O-N 3.15Å; F36-A39 PolarHBondContact O-N 3.32Å; F36-I40 HydrophobicContact CE1-CD1 3.95Å; F36-I40 HydrophobicContact CZ-CD1 4.19Å; F36-I40 PolarHBondContact O-N 3.16Å; F36-M65 HydrophobicContact CD1-CE 3.69Å; F36-M65 HydrophobicContact CD1-SD 4.09Å; F36-M65 HydrophobicContact CE1-CE 4.14Å; F36-M65 HydrophobicContact CE1-SD 4.36Å; F36-L100 HydrophobicContact CE1-CD1 3.87Å; F36-L100 HydrophobicContact CE1-CD2 4.05Å; F36-L100 HydrophobicContact CE1-CG 4.3Å; F36-L100 HydrophobicContact CE2-CD2 3.79Å; F36-L100 HydrophobicContact CZ-CD1 3.99Å; F36-L100 HydrophobicContact CZ-CD2 3.27Å; F36-L100 HydrophobicContact CZ-CG 3.96Å; F36-L124 HydrophobicContact CB-CD1 4.32Å; F36-L124 HydrophobicContact CD1-CD1 4.39Å; F36-L181 HydrophobicContact CE2-CB 4.27Å; F36-L181 HydrophobicContact CE2-CD1 4.23Å; F36-L181 HydrophobicContact CE2-CD2 4.41Å; F36-L181 HydrophobicContact CZ-CD1 4.49Å; F36-L185 HydrophobicContact CD2-CD1 4.29Å; F36-L185 HydrophobicContact CD2-CD2 4.49Å; F36-L185 HydrophobicContact CE1-CD1 4.45Å; F36-L185 HydrophobicContact CE2-CD1 4.08Å; F36-L185 HydrophobicContact CZ-CD1 4.22Å
37	P	92.2	Very high	92.1	Very high	4 Å²	4	10 Å²	10	3%	0.026	5%	0.046	C	C	.	.	H	α-helix	trans	-60.8	-27.4	175.1	-19.3	29.5	0	0	0	115.4	S33 T41 M65 L66 L124	S33-P37 VanDerWaalsContact O-CD 3.23Å; S33-P37 WeakPolarHBondContact O-CD 3.38Å; P37-T41 WeakPolarHBondContact O-CG2 3.49Å; P37-M65 HydrophobicContact CB-CE 3.54Å; P37-M65 HydrophobicContact CG-CE 3.65Å; P37-M65 HydrophobicContact CG-CG 4.39Å; P37-L66 HydrophobicContact CB-CD1 3.86Å; P37-L66 HydrophobicContact CG-CD1 3.77Å; P37-L124 HydrophobicContact CG-CD1 4.45Å
38	K	92.1	Very high	91.8	Very high	12 Å²	12	9.2 Å²	9.2	5%	0.052	4%	0.043	C	C	.	.	H	α-helix	trans	-86.9	-37.5	177.3	-61.9	169.3	-179.5	-177.3	0	111.1	A35 F36 I40 T41 L158 I262	A35-K38 PolarHBondContact O-N 3.13Å; A35-K38 VanDerWaalsContact O-N 3.08Å; F36-K38 PolarHBondContact O-N 3.15Å; K38-I40 VanDerWaalsContact C-N 3.32Å; K38-I40 PolarHBondContact O-N 3.27Å; K38-T41 WeakPolarHBondContact O-CG2 3.42Å; K38-T41 PolarHBondContact O-N 3.37Å; K38-T41 PolarHBondContact O-OG1 3.35Å; K38-L158 HydrophobicContact CB-CD1 3.71Å; K38-L158 HydrophobicContact CB-CD2 4.16Å; K38-L158 HydrophobicContact CD-CD2 3.76Å; K38-I262 HydrophobicContact CD-CD1 3.77Å; K38-I262 HydrophobicContact CG-CD1 4.31Å
39	A	92.8	Very high	91.5	Very high	0 Å²	0	13.7 Å²	13.7	0%	0	6%	0.061	C	C	.	.	H	α-helix	trans	-71.7	-26.9	-178.9	0	0	0	0	0	112.6	A35 F36 T41 V42 L158 L161 N165	A35-A39 WeakPolarHBondContact O-CB 3.49Å; A35-A39 PolarHBondContact O-N 2.94Å; F36-A39 PolarHBondContact O-N 3.32Å; A39-T41 PolarHBondContact O-N 3Å; A39-V42 WeakPolarHBondContact O-CG2 3.25Å; A39-L158 HydrophobicContact CB-CD1 4.07Å; A39-L161 HydrophobicContact CB-CB 3.89Å; A39-N165 PolarHBondContact O-ND2 3.28Å
40	I	91.6	Very high	91.3	Very high	1 Å²	1	17.9 Å²	17.9	1%	0.005	8%	0.082	C	C	.	.	G	3₁₀ helix	trans	-72	-15.8	178	-152.3	172.3	0	0	0	113	F36 K38 V42 Y43 F44 M65 I116 F178	F36-I40 HydrophobicContact CE1-CD1 3.95Å; F36-I40 HydrophobicContact CZ-CD1 4.19Å; F36-I40 PolarHBondContact O-N 3.16Å; K38-I40 VanDerWaalsContact C-N 3.32Å; K38-I40 PolarHBondContact O-N 3.27Å; I40-V42 PolarHBondContact O-N 3.27Å; I40-Y43 HydrophobicContact CG1-CD2 3.93Å; I40-Y43 HydrophobicContact CG1-CE2 4.49Å; I40-Y43 WeakPolarHBondContact O-CD2 3.34Å; I40-Y43 PolarHBondContact O-N 2.82Å; I40-Y43 VanDerWaalsContact O-N 3.13Å; I40-F44 HydrophobicContact CG2-CE1 3.92Å; I40-F44 HydrophobicContact CG2-CZ 4.13Å; I40-F44 WeakPolarHBondContact O-CD1 3.45Å; I40-M65 HydrophobicContact CG2-CE 4.19Å; I40-I116 HydrophobicContact CD1-CD1 3.92Å; I40-I116 HydrophobicContact CD1-CG2 3.71Å; I40-F178 HydrophobicContact CD1-CE1 3.89Å; I40-F178 HydrophobicContact CD1-CZ 4.04Å; I40-F178 HydrophobicContact CG1-CE1 3.94Å; I40-F178 HydrophobicContact CG1-CZ 4.26Å
41	T	91.4	Very high	91.2	Very high	1 Å²	1	20 Å²	20	1%	0.006	9%	0.092	C	C	.	.	G	3₁₀ helix	trans	-68.5	-17	-179.5	73	0	0	0	0	112.7	P37 K38 A39 Y43 F44 V263 T266	P37-T41 WeakPolarHBondContact O-CG2 3.49Å; K38-T41 WeakPolarHBondContact O-CG2 3.42Å; K38-T41 PolarHBondContact O-N 3.37Å; K38-T41 PolarHBondContact O-OG1 3.35Å; A39-T41 PolarHBondContact O-N 3Å; T41-Y43 PolarHBondContact O-N 2.9Å; T41-F44 HydrophobicContact CG2-CD2 4.07Å; T41-F44 HydrophobicContact CG2-CE2 3.69Å; T41-F44 HydrophobicContact CG2-CZ 4.05Å; T41-F44 VanDerWaalsContact O-CB 3.28Å; T41-F44 WeakPolarHBondContact O-CB 3.09Å; T41-F44 PolarHBondContact O-N 2.97Å; T41-F44 VanDerWaalsContact O-N 3.11Å; T41-V263 WeakPolarHBondContact CB-O 3.17Å; T41-V263 HydrophobicContact CG2-CB 4.35Å; T41-V263 HydrophobicContact CG2-CG1 4Å; T41-V263 HydrophobicContact CG2-CG2 4.37Å; T41-T266 PolarHBondContact O-OG1 3.32Å
42	V	91.9	Very high	91	Very high	3 Å²	3	27.3 Å²	27.3	2%	0.018	13%	0.13	C	C	.	.	G	3₁₀ helix	trans	-57.3	-34.8	171.8	177.6	0	0	0	0	111.6	A39 I40 F44 Q166 T266 K270 A280 L283	A39-V42 WeakPolarHBondContact O-CG2 3.25Å; I40-V42 PolarHBondContact O-N 3.27Å; V42-F44 VanDerWaalsContact C-N 3.35Å; V42-Q166 HydrophobicContact CG1-CB 4Å; V42-T266 HydrophobicContact CG2-CG2 4.27Å; V42-K270 PolarHBondContact O-NZ 3.3Å; V42-A280 HydrophobicContact CG1-CB 4.36Å; V42-A280 HydrophobicContact CG2-CB 4.28Å; V42-L283 HydrophobicContact CG2-CD1 4.19Å
43	Y	91.7	Very high	90.8	Very high	0 Å²	0	27.4 Å²	27.4	0%	0	13%	0.132	C	C	.	.	G	3₁₀ helix	trans	-80.6	-11.9	179.7	-59.2	-83.5	0	0	0	113.7	I40 T41 K45 D46 I47 N165 F169 W174 S177 F178 L181	I40-Y43 HydrophobicContact CG1-CD2 3.93Å; I40-Y43 HydrophobicContact CG1-CE2 4.49Å; I40-Y43 WeakPolarHBondContact O-CD2 3.34Å; I40-Y43 PolarHBondContact O-N 2.82Å; I40-Y43 VanDerWaalsContact O-N 3.13Å; T41-Y43 PolarHBondContact O-N 2.9Å; Y43-K45 PolarHBondContact O-N 3.47Å; Y43-D46 PolarHBondContact O-N 3Å; Y43-I47 WeakPolarHBondContact O-CB 3.36Å; Y43-I47 WeakPolarHBondContact O-CG1 3.44Å; Y43-I47 PolarHBondContact O-N 3.4Å; Y43-N165 HydrophobicContact CE2-CB 3.74Å; Y43-N165 WeakPolarHBondContact OH-CA 3.16Å; Y43-N165 WeakPolarHBondContact OH-CB 3.42Å; Y43-N165 PolarHBondContact OH-O 3.09Å; Y43-N165 VanDerWaalsContact OH-O 3.13Å; Y43-F169 HydrophobicContact CD1-CB 4.13Å; Y43-F169 AromaticContact CD1-CD2 3.59Å; Y43-F169 HydrophobicContact CD1-CD2 3.59Å; Y43-F169 HydrophobicContact CD1-CE2 4.42Å; Y43-F169 HydrophobicContact CD1-CG 4.13Å; Y43-F169 HydrophobicContact CE1-CB 3.67Å; Y43-F169 AromaticContact CE1-CD2 3.85Å; Y43-F169 HydrophobicContact CE1-CD2 3.85Å; Y43-F169 HydrophobicContact CE1-CG 4.15Å; Y43-W174 HydrophobicContact CD1-CB 4.24Å; Y43-S177 WeakPolarHBondContact OH-CB 3.2Å; Y43-F178 HydrophobicContact CD1-CE1 4.49Å; Y43-F178 AromaticContact CD2-CE1 3.95Å; Y43-F178 HydrophobicContact CD2-CE1 3.95Å; Y43-F178 HydrophobicContact CE2-CE1 4.12Å; Y43-F178 HydrophobicContact CG-CE1 4.16Å; Y43-F178 HydrophobicContact CG-CZ 4.5Å; Y43-L181 HydrophobicContact CE2-CD1 4.18Å
44	F	88.8	Confident	90.7	Very high	9 Å²	9	29.1 Å²	29.1	4%	0.039	14%	0.144	C	C	.	.	H	α-helix	trans	-63.1	-47.1	-166.8	-78.6	6.1	0	0	0	113.2	I40 T41 V42 D46 I47 Q48 I58 I61 S62 V263	I40-F44 HydrophobicContact CG2-CE1 3.92Å; I40-F44 HydrophobicContact CG2-CZ 4.13Å; I40-F44 WeakPolarHBondContact O-CD1 3.45Å; T41-F44 HydrophobicContact CG2-CD2 4.07Å; T41-F44 HydrophobicContact CG2-CE2 3.69Å; T41-F44 HydrophobicContact CG2-CZ 4.05Å; T41-F44 VanDerWaalsContact O-CB 3.28Å; T41-F44 WeakPolarHBondContact O-CB 3.09Å; T41-F44 PolarHBondContact O-N 2.97Å; T41-F44 VanDerWaalsContact O-N 3.11Å; V42-F44 VanDerWaalsContact C-N 3.35Å; F44-D46 PolarHBondContact O-N 3.21Å; F44-I47 PolarHBondContact O-N 3.21Å; F44-Q48 WeakPolarHBondContact O-CB 3.49Å; F44-Q48 PolarHBondContact O-N 3.01Å; F44-I58 HydrophobicContact CB-CG2 3.47Å; F44-I58 VanDerWaalsContact CB-CG2 3.47Å; F44-I58 HydrophobicContact CD1-CG2 3.61Å; F44-I58 HydrophobicContact CD2-CG2 3.47Å; F44-I58 VanDerWaalsContact CD2-CG2 3.47Å; F44-I58 HydrophobicContact CE1-CG2 4.11Å; F44-I58 HydrophobicContact CE2-CG2 3.98Å; F44-I58 HydrophobicContact CG-CG2 3.23Å; F44-I58 HydrophobicContact CZ-CG2 4.27Å; F44-I58 WeakPolarHBondContact O-CD1 3.3Å; F44-I61 HydrophobicContact CE1-CB 4.43Å; F44-I61 HydrophobicContact CZ-CB 4.32Å; F44-S62 WeakPolarHBondContact CE2-OG 3.31Å; F44-V263 HydrophobicContact CD2-CG1 4.25Å; F44-V263 HydrophobicContact CE2-CG1 3.84Å
45	K	87.6	Confident	90.6	Very high	29 Å²	29	29.2 Å²	29.2	13%	0.126	15%	0.145	C	C	.	.	H	α-helix	trans	-62	-31.8	179.8	-171.6	169.3	-172.9	164.3	0	112.2	Y43 Q48 K49 K270	Y43-K45 PolarHBondContact O-N 3.47Å; K45-Q48 VanDerWaalsContact O-CB 3.29Å; K45-Q48 WeakPolarHBondContact O-CB 3.49Å; K45-K49 WeakPolarHBondContact O-CG 3.42Å; K45-K49 PolarHBondContact O-N 3.28Å; K45-K270 HydrophobicContact CB-CD 4.25Å; K45-K270 HydrophobicContact CD-CB 3.51Å; K45-K270 HydrophobicContact CD-CD 3.82Å; K45-K270 HydrophobicContact CD-CG 4.29Å; K45-K270 PolarHBondContact NZ-O 3.02Å
46	D	87.3	Confident	90.6	Very high	13 Å²	13	30.1 Å²	30.1	7%	0.07	15%	0.151	C	C	.	.	H	α-helix	trans	-84.5	-41.6	-176	-59.6	-62.9	0	0	0	111.6	Y43 F44 Q48 K49 I50 F169 K270	Y43-D46 PolarHBondContact O-N 3Å; F44-D46 PolarHBondContact O-N 3.21Å; D46-Q48 PolarHBondContact O-N 3.05Å; D46-K49 PolarHBondContact O-N 2.97Å; D46-I50 WeakPolarHBondContact O-CD1 3.45Å; D46-I50 WeakPolarHBondContact O-CG1 3.42Å; D46-I50 PolarHBondContact O-N 3.31Å; D46-I50 VanDerWaalsContact O-N 3.08Å; D46-F169 HydrophobicContact CB-CE1 4.06Å; D46-F169 HydrophobicContact CB-CE2 3.85Å; D46-F169 HydrophobicContact CB-CZ 3.36Å; D46-K270 IonicContact OD2-NZ 3.08Å; D46-K270 PolarHBondContact OD2-NZ 2.98Å
47	I	89.4	Confident	90.6	Very high	3 Å²	3	34.3 Å²	34.3	2%	0.015	17%	0.17	C	C	.	.	H	α-helix	trans	-57	-35.9	167.9	-70.2	175.4	0	0	0	110.3	Y43 F44 I50 F51 L112 F178	Y43-I47 WeakPolarHBondContact O-CB 3.36Å; Y43-I47 WeakPolarHBondContact O-CG1 3.44Å; Y43-I47 PolarHBondContact O-N 3.4Å; F44-I47 PolarHBondContact O-N 3.21Å; I47-I50 PolarHBondContact O-N 3.09Å; I47-F51 HydrophobicContact CG2-CD2 3.7Å; I47-F51 HydrophobicContact CG2-CE2 4.13Å; I47-F51 WeakPolarHBondContact O-CD2 3.18Å; I47-F51 PolarHBondContact O-N 3.39Å; I47-L112 HydrophobicContact CG2-CD1 4.28Å; I47-F178 HydrophobicContact CD1-CE2 4.28Å; I47-F178 HydrophobicContact CD1-CZ 3.93Å
48	Q	89.8	Confident	90.5	Very high	26 Å²	26	34.3 Å²	34.3	12%	0.121	17%	0.17	C	C	.	.	H	α-helix	trans	-58.2	-49.5	175.3	-161.3	168.9	11.1	0	0	113.5	F44 K45 D46 I50 D52 C53 Y55 I58	F44-Q48 WeakPolarHBondContact O-CB 3.49Å; F44-Q48 PolarHBondContact O-N 3.01Å; K45-Q48 VanDerWaalsContact O-CB 3.29Å; K45-Q48 WeakPolarHBondContact O-CB 3.49Å; D46-Q48 PolarHBondContact O-N 3.05Å; Q48-I50 VanDerWaalsContact C-N 3.3Å; Q48-I50 PolarHBondContact O-N 3.24Å; Q48-D52 VanDerWaalsContact O-CA 3.29Å; Q48-D52 WeakPolarHBondContact O-CA 3.41Å; Q48-D52 PolarHBondContact O-N 3.15Å; Q48-C53 WeakPolarHBondContact CG-O 3.4Å; Q48-C53 PolarHBondContact NE2-O 3.24Å; Q48-C53 VanDerWaalsContact NE2-O 3.07Å; Q48-C53 PolarHBondContact O-N 3.03Å; Q48-Y55 VanDerWaalsContact NE2-CD1 3.35Å; Q48-Y55 VanDerWaalsContact OE1-CD1 3.29Å; Q48-I58 HydrophobicContact CB-CD1 3.19Å; Q48-I58 HydrophobicContact CG-CD1 3.43Å; Q48-I58 VanDerWaalsContact CG-CD1 3.43Å
49	K	88.8	Confident	90.6	Very high	138 Å²	138	33.8 Å²	33.8	60%	0.6	17%	0.168	S	C	*	.	H	α-helix	trans	-66.1	-36.1	-179.8	-68	170.2	-177.7	172.5	0	111.3	K45 D46	K45-K49 WeakPolarHBondContact O-CG 3.42Å; K45-K49 PolarHBondContact O-N 3.28Å; D46-K49 PolarHBondContact O-N 2.97Å
50	I	89.9	Confident	90.7	Very high	88 Å²	88	38 Å²	38	45%	0.451	18%	0.184	S	C	.	.	H	α-helix	trans	-72	-42.2	-177.8	-68.6	160.3	0	0	0	111.8	D46 I47 Q48 W174	D46-I50 WeakPolarHBondContact O-CD1 3.45Å; D46-I50 WeakPolarHBondContact O-CG1 3.42Å; D46-I50 PolarHBondContact O-N 3.31Å; D46-I50 VanDerWaalsContact O-N 3.08Å; I47-I50 PolarHBondContact O-N 3.09Å; Q48-I50 VanDerWaalsContact C-N 3.3Å; Q48-I50 PolarHBondContact O-N 3.24Å; I50-W174 VanDerWaalsContact CD1-CD1 3.47Å
51	F	90.4	Very high	90.8	Very high	45 Å²	45	38 Å²	38	20%	0.197	18%	0.184	C	C	.	.	H	α-helix	trans	-100.1	5.1	-176.3	-68	-70.7	0	0	0	114	I47 C53 N107 V109 L112 W174	I47-F51 HydrophobicContact CG2-CD2 3.7Å; I47-F51 HydrophobicContact CG2-CE2 4.13Å; I47-F51 WeakPolarHBondContact O-CD2 3.18Å; I47-F51 PolarHBondContact O-N 3.39Å; F51-C53 PolarHBondContact O-N 2.91Å; F51-N107 VanDerWaalsContact CE1-O 3.29Å; F51-N107 WeakPolarHBondContact CE1-O 3.47Å; F51-V109 HydrophobicContact CB-CG2 3.68Å; F51-V109 HydrophobicContact CD1-CG2 4.49Å; F51-V109 HydrophobicContact CD2-CG2 4.32Å; F51-V109 HydrophobicContact CG-CG2 3.93Å; F51-L112 HydrophobicContact CE2-CD1 4.18Å; F51-W174 HydrophobicContact CE2-CH2 4.04Å; F51-W174 AromaticContact CE2-CZ2 3.83Å; F51-W174 HydrophobicContact CE2-CZ2 3.83Å; F51-W174 AromaticContact CZ-CH2 3.88Å; F51-W174 HydrophobicContact CZ-CH2 3.88Å; F51-W174 AromaticContact CZ-CZ2 3.73Å; F51-W174 HydrophobicContact CZ-CZ2 3.73Å
52	D	89.4	Confident	90.9	Very high	153 Å²	153	38.1 Å²	38.1	82%	0.818	19%	0.185	S	C	*	.	T	Hydrogen-bonded Turn	trans	44.2	48.7	-177	-164.6	35	0	0	0	113.2	Q48	Q48-D52 VanDerWaalsContact O-CA 3.29Å; Q48-D52 WeakPolarHBondContact O-CA 3.41Å; Q48-D52 PolarHBondContact O-N 3.15Å
53	C	89.4	Confident	91	Very high	12 Å²	12	38.1 Å²	38.1	8%	0.081	19%	0.185	C	C	.	.			trans	-106.9	162.4	-172.8	57.8	0	0	0	0	112.6	Q48 F51 Q57 I58 V109	Q48-C53 WeakPolarHBondContact CG-O 3.4Å; Q48-C53 PolarHBondContact NE2-O 3.24Å; Q48-C53 VanDerWaalsContact NE2-O 3.07Å; Q48-C53 PolarHBondContact O-N 3.03Å; F51-C53 PolarHBondContact O-N 2.91Å; C53-Q57 HydrophobicContact CB-CB 4.24Å; C53-I58 WeakPolarHBondContact SG-CD1 3.43Å; C53-I58 WeakPolarHBondContact SG-CG1 3.46Å; C53-V109 HydrophobicContact CB-CG2 4.21Å
54	S	92.4	Very high	91.2	Very high	36 Å²	36	39.6 Å²	39.6	25%	0.252	19%	0.193	S	C	.	.			trans	-79.7	160.1	-179.1	101.8	0	0	0	0	111.9	S56 Q57 I58 D395	S54-S56 PolarHBondContact O-N 3.39Å; S54-S56 WeakPolarHBondContact OG-CB 3.34Å; S54-S56 PolarHBondContact OG-N 3.42Å; S54-Q57 PolarHBondContact O-N 2.98Å; S54-Q57 VanDerWaalsContact O-N 3.13Å; S54-Q57 PolarHBondContact OG-N 3.35Å; S54-I58 PolarHBondContact O-N 2.93Å; S54-D395 WeakPolarHBondContact CB-OD2 3.42Å; S54-D395 PolarHBondContact OG-OD2 3.28Å
55	Y	89.5	Confident	91.5	Very high	39 Å²	39	39.2 Å²	39.2	15%	0.153	19%	0.191	C	C	.	.	H	α-helix	trans	-59.3	-37.1	174.9	-68.7	-66.7	0	0	0	111.7	Q48 A59 V394 D395 Y400	Q48-Y55 VanDerWaalsContact NE2-CD1 3.35Å; Q48-Y55 VanDerWaalsContact OE1-CD1 3.29Å; Y55-A59 WeakPolarHBondContact O-CB 3.21Å; Y55-A59 PolarHBondContact O-N 3.11Å; Y55-A59 VanDerWaalsContact O-N 3.1Å; Y55-V394 HydrophobicContact CD2-CB 4.21Å; Y55-V394 HydrophobicContact CD2-CG1 3.67Å; Y55-V394 HydrophobicContact CE2-CG1 3.88Å; Y55-V394 HydrophobicContact CG-CG1 4.24Å; Y55-D395 WeakPolarHBondContact CB-OD1 3.4Å; Y55-D395 WeakPolarHBondContact CD2-OD1 3.34Å; Y55-D395 PolarHBondContact N-OD1 3.27Å; Y55-D395 PolarHBondContact N-OD2 3.3Å; Y55-Y400 WeakPolarHBondContact CD1-OH 3.46Å; Y55-Y400 AromaticContact CE1-CZ 3.9Å; Y55-Y400 WeakPolarHBondContact CE1-OH 3.23Å; Y55-Y400 PolarHBondContact OH-OH 3.22Å
56	S	92.5	Very high	91.8	Very high	18 Å²	18	38.4 Å²	38.4	13%	0.126	19%	0.188	C	C	.	.	H	α-helix	trans	-59.4	-47.5	173.3	-169.4	0	0	0	0	112	S54 I58 A59 W60 P388 D395	S54-S56 PolarHBondContact O-N 3.39Å; S54-S56 WeakPolarHBondContact OG-CB 3.34Å; S54-S56 PolarHBondContact OG-N 3.42Å; S56-I58 PolarHBondContact O-N 3.16Å; S56-A59 PolarHBondContact O-N 3.11Å; S56-W60 PolarHBondContact O-N 3.25Å; S56-P388 WeakPolarHBondContact CB-O 3.25Å; S56-P388 PolarHBondContact OG-O 3.48Å; S56-D395 WeakPolarHBondContact CB-OD2 3.07Å; S56-D395 PolarHBondContact N-OD2 3.35Å
57	Q	93	Very high	92.1	Very high	90 Å²	90	38 Å²	38	42%	0.421	19%	0.187	S	C	.	.	H	α-helix	trans	-59.7	-47.6	-179.3	-73.6	175.1	-34.4	0	0	111.5	C53 S54 A59 W60 Y113	C53-Q57 HydrophobicContact CB-CB 4.24Å; S54-Q57 PolarHBondContact O-N 2.98Å; S54-Q57 VanDerWaalsContact O-N 3.13Å; S54-Q57 PolarHBondContact OG-N 3.35Å; Q57-A59 VanDerWaalsContact C-N 3.35Å; Q57-A59 PolarHBondContact O-N 3.31Å; Q57-W60 WeakPolarHBondContact O-CB 3.41Å; Q57-W60 PolarHBondContact O-N 3.25Å; Q57-Y113 WeakPolarHBondContact CA-OH 3.46Å; Q57-Y113 VanDerWaalsContact O-CE1 3.29Å; Q57-Y113 WeakPolarHBondContact O-CE1 3.05Å; Q57-Y113 PolarHBondContact O-OH 3.45Å
58	I	92.1	Very high	92.4	Very high	5 Å²	5	39 Å²	39	3%	0.026	19%	0.193	C	C	.	.	H	α-helix	trans	-66.8	-37.5	179.5	-73.1	158.6	0	0	0	113	F44 Q48 C53 S54 S56 W60 I61	F44-I58 HydrophobicContact CB-CG2 3.47Å; F44-I58 VanDerWaalsContact CB-CG2 3.47Å; F44-I58 HydrophobicContact CD1-CG2 3.61Å; F44-I58 HydrophobicContact CD2-CG2 3.47Å; F44-I58 VanDerWaalsContact CD2-CG2 3.47Å; F44-I58 HydrophobicContact CE1-CG2 4.11Å; F44-I58 HydrophobicContact CE2-CG2 3.98Å; F44-I58 HydrophobicContact CG-CG2 3.23Å; F44-I58 HydrophobicContact CZ-CG2 4.27Å; F44-I58 WeakPolarHBondContact O-CD1 3.3Å; Q48-I58 HydrophobicContact CB-CD1 3.19Å; Q48-I58 HydrophobicContact CG-CD1 3.43Å; Q48-I58 VanDerWaalsContact CG-CD1 3.43Å; C53-I58 WeakPolarHBondContact SG-CD1 3.43Å; C53-I58 WeakPolarHBondContact SG-CG1 3.46Å; S54-I58 PolarHBondContact O-N 2.93Å; S56-I58 PolarHBondContact O-N 3.16Å; I58-W60 PolarHBondContact O-N 3.39Å; I58-W60 VanDerWaalsContact O-N 3.17Å; I58-I61 WeakPolarHBondContact O-CB 3.42Å; I58-I61 WeakPolarHBondContact O-CG1 3.36Å; I58-I61 PolarHBondContact O-N 2.99Å
59	A	93.2	Very high	92.6	Very high	0 Å²	0	37.9 Å²	37.9	0%	0	19%	0.188	C	C	.	.	H	α-helix	trans	-60.8	-27.2	179.6	0	0	0	0	0	112.7	Y55 S56 Q57 I61 S62 S63 F264 P387 P388	Y55-A59 WeakPolarHBondContact O-CB 3.21Å; Y55-A59 PolarHBondContact O-N 3.11Å; Y55-A59 VanDerWaalsContact O-N 3.1Å; S56-A59 PolarHBondContact O-N 3.11Å; Q57-A59 VanDerWaalsContact C-N 3.35Å; Q57-A59 PolarHBondContact O-N 3.31Å; A59-I61 PolarHBondContact O-N 3.45Å; A59-S62 PolarHBondContact O-N 3.47Å; A59-S62 PolarHBondContact O-OG 3.04Å; A59-S63 WeakPolarHBondContact O-CB 3.41Å; A59-S63 PolarHBondContact O-N 2.93Å; A59-S63 VanDerWaalsContact O-N 3.09Å; A59-S63 PolarHBondContact O-OG 2.95Å; A59-F264 HydrophobicContact CB-CE1 4.32Å; A59-F264 HydrophobicContact CB-CE2 4.31Å; A59-F264 HydrophobicContact CB-CZ 3.59Å; A59-P387 HydrophobicContact CB-CB 4.1Å; A59-P388 HydrophobicContact CB-CG 4.45Å
60	W	95.2	Very high	92.7	Very high	88 Å²	88	32.7 Å²	32.7	33%	0.333	16%	0.164	S	C	.	.	H	α-helix	trans	-57.6	-32.1	172.4	-78.5	104.6	0	0	0	112.7	S56 Q57 I58 S63 I64 Y113 L384 P388	S56-W60 PolarHBondContact O-N 3.25Å; Q57-W60 WeakPolarHBondContact O-CB 3.41Å; Q57-W60 PolarHBondContact O-N 3.25Å; I58-W60 PolarHBondContact O-N 3.39Å; I58-W60 VanDerWaalsContact O-N 3.17Å; W60-S63 PolarHBondContact O-N 3.38Å; W60-I64 HydrophobicContact CB-CD1 4.12Å; W60-I64 HydrophobicContact CE3-CD1 4.11Å; W60-I64 HydrophobicContact CE3-CG1 3.95Å; W60-I64 VanDerWaalsContact O-CB 3.27Å; W60-I64 WeakPolarHBondContact O-CB 3.47Å; W60-I64 WeakPolarHBondContact O-CD1 3.5Å; W60-I64 WeakPolarHBondContact O-CG1 3.36Å; W60-I64 PolarHBondContact O-N 3.43Å; W60-Y113 HydrophobicContact CB-CD1 4.17Å; W60-Y113 HydrophobicContact CB-CE1 3.6Å; W60-L384 HydrophobicContact CE3-CD1 4.02Å; W60-L384 HydrophobicContact CZ3-CD1 3.67Å; W60-L384 HydrophobicContact CZ3-CD2 4.43Å; W60-L384 HydrophobicContact CZ3-CG 3.76Å; W60-P388 HydrophobicContact CB-CG 4.46Å; W60-P388 HydrophobicContact CD2-CB 3.87Å; W60-P388 HydrophobicContact CD2-CG 3.52Å; W60-P388 VanDerWaalsContact CE2-CB 3.47Å; W60-P388 HydrophobicContact CE3-CG 3.93Å; W60-P388 HydrophobicContact CG-CB 4.06Å; W60-P388 HydrophobicContact CG-CG 3.77Å; W60-P388 HydrophobicContact CZ2-CB 3.91Å; W60-P388 HydrophobicContact CZ2-CG 4.16Å; W60-P388 HydrophobicContact CZ3-CG 4.42Å
61	I	93.8	Very high	92.7	Very high	2 Å²	2	30.4 Å²	30.4	1%	0.01	16%	0.158	C	C	.	.	H	α-helix	trans	-59.2	-56.9	179.7	-57.3	173.5	0	0	0	110.6	F44 I58 A59 S63 M65 L112 Y113 I116	F44-I61 HydrophobicContact CE1-CB 4.43Å; F44-I61 HydrophobicContact CZ-CB 4.32Å; I58-I61 WeakPolarHBondContact O-CB 3.42Å; I58-I61 WeakPolarHBondContact O-CG1 3.36Å; I58-I61 PolarHBondContact O-N 2.99Å; A59-I61 PolarHBondContact O-N 3.45Å; I61-S63 VanDerWaalsContact C-N 3.32Å; I61-S63 PolarHBondContact O-N 3.24Å; I61-M65 WeakPolarHBondContact O-CB 3.32Å; I61-M65 PolarHBondContact O-N 3.45Å; I61-M65 VanDerWaalsContact O-N 3.14Å; I61-L112 HydrophobicContact CD1-CB 4.22Å; I61-L112 HydrophobicContact CD1-CD1 4.31Å; I61-Y113 HydrophobicContact CG1-CD1 3.65Å; I61-Y113 HydrophobicContact CG1-CE1 3.65Å; I61-I116 HydrophobicContact CG2-CB 4.05Å; I61-I116 HydrophobicContact CG2-CD1 4.37Å; I61-I116 HydrophobicContact CG2-CG2 3.82Å
62	S	92.5	Very high	92.6	Very high	4 Å²	4	28.3 Å²	28.3	3%	0.028	15%	0.149	C	C	.	.	H	α-helix	trans	-66.2	-34.5	178.8	52.3	0	0	0	0	112.7	F44 A59 M65 L66	F44-S62 WeakPolarHBondContact CE2-OG 3.31Å; A59-S62 PolarHBondContact O-N 3.47Å; A59-S62 PolarHBondContact O-OG 3.04Å; S62-M65 PolarHBondContact O-N 3.32Å; S62-L66 WeakPolarHBondContact O-CB 3.26Å; S62-L66 PolarHBondContact O-N 3.21Å
63	S	94.6	Very high	92.4	Very high	2 Å²	2	21.4 Å²	21.4	1%	0.014	11%	0.114	C	C	.	.	H	α-helix	trans	-73.9	-42.2	-174.8	-51.4	0	0	0	0	111.7	A59 W60 I61 M65 L66 A67 L384 P387 P388	A59-S63 WeakPolarHBondContact O-CB 3.41Å; A59-S63 PolarHBondContact O-N 2.93Å; A59-S63 VanDerWaalsContact O-N 3.09Å; A59-S63 PolarHBondContact O-OG 2.95Å; W60-S63 PolarHBondContact O-N 3.38Å; I61-S63 VanDerWaalsContact C-N 3.32Å; I61-S63 PolarHBondContact O-N 3.24Å; S63-M65 VanDerWaalsContact C-N 3.33Å; S63-L66 PolarHBondContact O-N 2.87Å; S63-A67 WeakPolarHBondContact O-CB 3.11Å; S63-A67 PolarHBondContact O-N 3.3Å; S63-L384 WeakPolarHBondContact CB-O 3.29Å; S63-P387 VanDerWaalsContact OG-CB 3.26Å; S63-P387 WeakPolarHBondContact OG-CB 3.28Å; S63-P387 VanDerWaalsContact OG-CG 3.24Å; S63-P387 WeakPolarHBondContact OG-CG 3Å; S63-P388 WeakPolarHBondContact OG-CD 3.43Å
64	I	96	Very high	92.2	Very high	32 Å²	32	22.6 Å²	22.6	16%	0.164	12%	0.122	C	C	.	.	H	α-helix	trans	-62	-45.6	171.8	-65.5	165.6	0	0	0	109.1	W60 L66 A67 V68 Y113 L384	W60-I64 HydrophobicContact CB-CD1 4.12Å; W60-I64 HydrophobicContact CE3-CD1 4.11Å; W60-I64 HydrophobicContact CE3-CG1 3.95Å; W60-I64 VanDerWaalsContact O-CB 3.27Å; W60-I64 WeakPolarHBondContact O-CB 3.47Å; W60-I64 WeakPolarHBondContact O-CD1 3.5Å; W60-I64 WeakPolarHBondContact O-CG1 3.36Å; W60-I64 PolarHBondContact O-N 3.43Å; I64-L66 PolarHBondContact O-N 3.5Å; I64-A67 PolarHBondContact O-N 2.84Å; I64-V68 HydrophobicContact CG2-CG2 3.95Å; I64-V68 VanDerWaalsContact O-CB 3.26Å; I64-V68 WeakPolarHBondContact O-CB 3.24Å; I64-V68 WeakPolarHBondContact O-CG2 3.38Å; I64-V68 PolarHBondContact O-N 3.27Å; I64-Y113 HydrophobicContact CD1-CD1 4.18Å; I64-Y113 HydrophobicContact CD1-CD2 4.43Å; I64-Y113 HydrophobicContact CD1-CG 3.93Å; I64-L384 HydrophobicContact CB-CD1 4.37Å; I64-L384 HydrophobicContact CG1-CD1 3.74Å
65	M	95.5	Very high	92	Very high	0 Å²	0	25 Å²	25	0%	0	13%	0.131	C	C	.	.	H	α-helix	trans	-59	-46.6	179.5	-167.9	158.5	67.4	0	0	112.4	F36 P37 I40 I61 S62 S63 M69 I116 G117 L124	F36-M65 HydrophobicContact CD1-CE 3.69Å; F36-M65 HydrophobicContact CD1-SD 4.09Å; F36-M65 HydrophobicContact CE1-CE 4.14Å; F36-M65 HydrophobicContact CE1-SD 4.36Å; P37-M65 HydrophobicContact CB-CE 3.54Å; P37-M65 HydrophobicContact CG-CE 3.65Å; P37-M65 HydrophobicContact CG-CG 4.39Å; I40-M65 HydrophobicContact CG2-CE 4.19Å; I61-M65 WeakPolarHBondContact O-CB 3.32Å; I61-M65 PolarHBondContact O-N 3.45Å; I61-M65 VanDerWaalsContact O-N 3.14Å; S62-M65 PolarHBondContact O-N 3.32Å; S63-M65 VanDerWaalsContact C-N 3.33Å; M65-M69 VanDerWaalsContact O-CB 3.3Å; M65-M69 WeakPolarHBondContact O-CB 3.49Å; M65-M69 PolarHBondContact O-N 3.29Å; M65-I116 HydrophobicContact CE-CG2 4.28Å; M65-I116 HydrophobicContact SD-CG2 3.71Å; M65-I116 VanDerWaalsContact SD-O 3.34Å; M65-G117 WeakPolarHBondContact CA-O 3.48Å; M65-L124 HydrophobicContact CG-CD1 4.42Å; M65-L124 HydrophobicContact SD-CD1 4.21Å
66	L	93.1	Very high	91.9	Very high	13 Å²	13	23.1 Å²	23.1	7%	0.068	12%	0.124	C	C	.	.	H	α-helix	trans	-70.7	-40.9	-179.7	-151.9	71.3	0	0	0	111.7	P37 S62 S63 I64 M69 Y70 F259 V383	P37-L66 HydrophobicContact CB-CD1 3.86Å; P37-L66 HydrophobicContact CG-CD1 3.77Å; S62-L66 WeakPolarHBondContact O-CB 3.26Å; S62-L66 PolarHBondContact O-N 3.21Å; S63-L66 PolarHBondContact O-N 2.87Å; I64-L66 PolarHBondContact O-N 3.5Å; L66-M69 HydrophobicContact CD1-CE 3.69Å; L66-M69 WeakPolarHBondContact O-CB 3.3Å; L66-M69 PolarHBondContact O-N 3.44Å; L66-Y70 HydrophobicContact CD1-CE1 4.26Å; L66-Y70 HydrophobicContact CG-CD1 4.36Å; L66-Y70 HydrophobicContact CG-CE1 4Å; L66-Y70 WeakPolarHBondContact O-CD1 3.49Å; L66-Y70 PolarHBondContact O-N 2.78Å; L66-F259 HydrophobicContact CD2-CD1 3.86Å; L66-F259 HydrophobicContact CD2-CD2 3.97Å; L66-F259 HydrophobicContact CD2-CE1 3.8Å; L66-F259 HydrophobicContact CD2-CE2 3.86Å; L66-F259 HydrophobicContact CD2-CG 3.96Å; L66-F259 HydrophobicContact CD2-CZ 3.79Å; L66-V383 HydrophobicContact CB-CG1 3.8Å; L66-V383 HydrophobicContact CD2-CG1 3.69Å; L66-V383 HydrophobicContact CG-CG1 3.95Å
67	A	94.8	Very high	91.5	Very high	5 Å²	5	23.5 Å²	23.5	4%	0.041	13%	0.127	C	C	.	.	H	α-helix	trans	-64.5	-44	177.5	0	0	0	0	0	112.3	S63 I64 M69 Y70 A71 L384	S63-A67 WeakPolarHBondContact O-CB 3.11Å; S63-A67 PolarHBondContact O-N 3.3Å; I64-A67 PolarHBondContact O-N 2.84Å; A67-M69 VanDerWaalsContact C-N 3.32Å; A67-Y70 PolarHBondContact O-N 3.2Å; A67-A71 VanDerWaalsContact O-CB 3.28Å; A67-A71 WeakPolarHBondContact O-CB 3.18Å; A67-A71 PolarHBondContact O-N 3.42Å; A67-L384 HydrophobicContact CB-CB 3.75Å; A67-L384 HydrophobicContact CB-CD1 3.92Å; A67-L384 HydrophobicContact CB-CG 4.32Å
68	V	95.3	Very high	91	Very high	23 Å²	23	21.8 Å²	21.8	14%	0.139	12%	0.122	C	C	.	.	H	α-helix	trans	-65.8	-37.8	175.7	173.6	0	0	0	0	110.6	I64 Y70 G72 L118 L122	I64-V68 HydrophobicContact CG2-CG2 3.95Å; I64-V68 VanDerWaalsContact O-CB 3.26Å; I64-V68 WeakPolarHBondContact O-CB 3.24Å; I64-V68 WeakPolarHBondContact O-CG2 3.38Å; I64-V68 PolarHBondContact O-N 3.27Å; V68-Y70 VanDerWaalsContact C-N 3.32Å; V68-Y70 PolarHBondContact O-N 3.12Å; V68-G72 WeakPolarHBondContact O-CA 3.39Å; V68-G72 PolarHBondContact O-N 3.19Å; V68-L118 HydrophobicContact CG1-CD1 4.22Å; V68-L118 HydrophobicContact CG2-CD1 3.9Å; V68-L122 HydrophobicContact CG1-CB 4.27Å; V68-L122 HydrophobicContact CG1-CD2 3.73Å; V68-L122 HydrophobicContact CG1-CG 3.54Å
69	M	93.8	Very high	90.5	Very high	3 Å²	3	23.4 Å²	23.4	2%	0.015	13%	0.131	C	C	.	.	H	α-helix	trans	-59.7	-43.5	174.2	-174.1	-177.5	74.9	0	0	111.9	Y34 M65 L66 A67 L124 A125 L128	Y34-M69 HydrophobicContact CD1-CE 3.83Å; Y34-M69 HydrophobicContact CE1-CE 3.77Å; M65-M69 VanDerWaalsContact O-CB 3.3Å; M65-M69 WeakPolarHBondContact O-CB 3.49Å; M65-M69 PolarHBondContact O-N 3.29Å; L66-M69 HydrophobicContact CD1-CE 3.69Å; L66-M69 WeakPolarHBondContact O-CB 3.3Å; L66-M69 PolarHBondContact O-N 3.44Å; A67-M69 VanDerWaalsContact C-N 3.32Å; M69-L124 HydrophobicContact CG-CB 4.32Å; M69-L124 HydrophobicContact SD-CB 4.22Å; M69-A125 WeakPolarHBondContact O-CB 3.32Å; M69-L128 HydrophobicContact CE-CD2 4.29Å; M69-L128 HydrophobicContact CG-CD2 4.31Å; M69-L128 HydrophobicContact SD-CD2 4.21Å
70	Y	90.3	Very high	90	Very high	29 Å²	29	23.5 Å²	23.5	11%	0.114	13%	0.131	C	C	.	.	H	α-helix	trans	-72.6	-46.7	-179.8	-82.3	50.1	0	0	0	111.7	Y34 L66 A67 V68 G72 G73 T376 E379	Y34-Y70 HydrophobicContact CE1-CE1 4.24Å; L66-Y70 HydrophobicContact CD1-CE1 4.26Å; L66-Y70 HydrophobicContact CG-CD1 4.36Å; L66-Y70 HydrophobicContact CG-CE1 4Å; L66-Y70 WeakPolarHBondContact O-CD1 3.49Å; L66-Y70 PolarHBondContact O-N 2.78Å; A67-Y70 PolarHBondContact O-N 3.2Å; V68-Y70 VanDerWaalsContact C-N 3.32Å; V68-Y70 PolarHBondContact O-N 3.12Å; Y70-G72 PolarHBondContact O-N 3.01Å; Y70-G73 PolarHBondContact O-N 2.81Å; Y70-T376 HydrophobicContact CD2-CG2 4.48Å; Y70-E379 HydrophobicContact CD2-CB 4.47Å
71	A	90.2	Very high	89.3	Confident	39 Å²	39	22.4 Å²	22.4	32%	0.322	13%	0.132	S	C	.	.	H	α-helix	trans	-66.9	-25.3	177.5	0	0	0	0	0	112.9	A67 G73 P74 C380	A67-A71 VanDerWaalsContact O-CB 3.28Å; A67-A71 WeakPolarHBondContact O-CB 3.18Å; A67-A71 PolarHBondContact O-N 3.42Å; A71-G73 VanDerWaalsContact C-N 3.29Å; A71-G73 PolarHBondContact O-N 2.98Å; A71-P74 WeakPolarHBondContact O-CD 3.3Å; A71-C380 HydrophobicContact CB-CB 4.29Å
72	G	87.9	Confident	88.7	Confident	1 Å²	1	26.2 Å²	26.2	1%	0.01	16%	0.155	C	C	.	.	H	α-helix	trans	-74	-12.7	177.3	0	0	0	0	0	114.6	V68 Y70 I75 S76	V68-G72 WeakPolarHBondContact O-CA 3.39Å; V68-G72 PolarHBondContact O-N 3.19Å; Y70-G72 PolarHBondContact O-N 3.01Å; G72-I75 PolarHBondContact O-N 3.18Å; G72-S76 WeakPolarHBondContact O-CB 3.19Å; G72-S76 PolarHBondContact O-N 2.94Å
73	G	86.3	Confident	88.4	Confident	8 Å²	8	34.2 Å²	34.2	8%	0.082	19%	0.186	C	C	.	.	H	α-helix	trans	-57.1	-55.2	-179.2	0	0	0	0	0	114.1	Y70 A71 I75 S76 S77	Y70-G73 PolarHBondContact O-N 2.81Å; A71-G73 VanDerWaalsContact C-N 3.29Å; A71-G73 PolarHBondContact O-N 2.98Å; G73-I75 VanDerWaalsContact C-N 3.34Å; G73-I75 PolarHBondContact O-N 3.13Å; G73-S76 WeakPolarHBondContact O-CB 3.26Å; G73-S76 PolarHBondContact O-N 3.25Å; G73-S77 PolarHBondContact O-N 3.05Å
74	P	84.1	Confident	87.9	Confident	37 Å²	37	34.9 Å²	34.9	24%	0.24	19%	0.194	C	C	.	.	H	α-helix	trans	-57.9	-42.8	175.7	-23	29.5	0	0	0	113.3	A71 S77 V78 I377	A71-P74 WeakPolarHBondContact O-CD 3.3Å; P74-S77 WeakPolarHBondContact O-CB 3.4Å; P74-S77 PolarHBondContact O-N 3.36Å; P74-V78 WeakPolarHBondContact O-CG2 3.46Å; P74-V78 PolarHBondContact O-N 2.86Å; P74-I377 HydrophobicContact CG-CD1 3.6Å; P74-I377 HydrophobicContact CG-CG1 3.67Å
75	I	88.1	Confident	87.5	Confident	86 Å²	86	33.9 Å²	33.9	44%	0.441	19%	0.189	S	C	.	.	H	α-helix	trans	-60.3	-50	177.2	-63	166.8	0	0	0	109	G72 G73 S77 V78 L79 F126	G72-I75 PolarHBondContact O-N 3.18Å; G73-I75 VanDerWaalsContact C-N 3.34Å; G73-I75 PolarHBondContact O-N 3.13Å; I75-S77 VanDerWaalsContact C-N 3.28Å; I75-S77 PolarHBondContact O-N 3.17Å; I75-V78 PolarHBondContact O-N 3.49Å; I75-L79 HydrophobicContact CG2-CD1 3.65Å; I75-L79 WeakPolarHBondContact O-CD1 3.32Å; I75-L79 PolarHBondContact O-N 3.47Å; I75-F126 HydrophobicContact CG2-CE1 3.96Å; I75-F126 HydrophobicContact CG2-CZ 4.14Å
76	S	88.3	Confident	87.4	Confident	0 Å²	0	39.7 Å²	39.7	0%	0	21%	0.211	C	C	.	.	H	α-helix	trans	-58.4	-39.3	176.5	-167.8	0	0	0	0	112.4	G72 G73 L79 V80	G72-S76 WeakPolarHBondContact O-CB 3.19Å; G72-S76 PolarHBondContact O-N 2.94Å; G73-S76 WeakPolarHBondContact O-CB 3.26Å; G73-S76 PolarHBondContact O-N 3.25Å; S76-L79 PolarHBondContact O-N 3.45Å; S76-V80 WeakPolarHBondContact O-CB 3.47Å; S76-V80 WeakPolarHBondContact O-CG2 3.21Å; S76-V80 PolarHBondContact O-N 3.23Å
77	S	82.9	Confident	87.4	Confident	27 Å²	27	42.5 Å²	42.5	19%	0.189	23%	0.23	C	C	.	.	H	α-helix	trans	-62.2	-44.7	178	-175.9	0	0	0	0	111.7	G73 P74 I75 V80 N81	G73-S77 PolarHBondContact O-N 3.05Å; P74-S77 WeakPolarHBondContact O-CB 3.4Å; P74-S77 PolarHBondContact O-N 3.36Å; I75-S77 VanDerWaalsContact C-N 3.28Å; I75-S77 PolarHBondContact O-N 3.17Å; S77-V80 PolarHBondContact O-N 3.4Å; S77-N81 VanDerWaalsContact O-CG 3.28Å; S77-N81 PolarHBondContact O-N 3.07Å; S77-N81 PolarHBondContact O-ND2 3.47Å; S77-N81 VanDerWaalsContact O-ND2 3.1Å
78	V	82.3	Confident	87.3	Confident	54 Å²	54	42.4 Å²	42.4	33%	0.327	23%	0.229	S	C	.	.	H	α-helix	trans	-61.3	-47.6	175.5	175	0	0	0	0	110.7	P74 I75 V80 N81 T82 F233	P74-V78 WeakPolarHBondContact O-CG2 3.46Å; P74-V78 PolarHBondContact O-N 2.86Å; I75-V78 PolarHBondContact O-N 3.49Å; V78-V80 VanDerWaalsContact C-N 3.31Å; V78-V80 PolarHBondContact O-N 3Å; V78-N81 PolarHBondContact O-N 3.22Å; V78-T82 PolarHBondContact O-N 2.87Å; V78-T82 VanDerWaalsContact O-N 3.11Å; V78-T82 PolarHBondContact O-OG1 3.5Å; V78-F233 HydrophobicContact CG2-CD2 4.39Å; V78-F233 HydrophobicContact CG2-CE2 4.43Å
79	L	83.6	Confident	87.3	Confident	39 Å²	39	41.3 Å²	41.3	20%	0.204	22%	0.222	C	C	.	.	H	α-helix	trans	-62.2	-37.6	178.2	-85.9	85.9	0	0	0	112.7	I75 S76 N81 T82 Y83 V88 M91 F126	I75-L79 HydrophobicContact CG2-CD1 3.65Å; I75-L79 WeakPolarHBondContact O-CD1 3.32Å; I75-L79 PolarHBondContact O-N 3.47Å; S76-L79 PolarHBondContact O-N 3.45Å; L79-N81 VanDerWaalsContact C-N 3.32Å; L79-T82 WeakPolarHBondContact CA-OG1 3.29Å; L79-T82 PolarHBondContact O-N 3.49Å; L79-T82 PolarHBondContact O-OG1 3.29Å; L79-T82 VanDerWaalsContact O-OG1 3.05Å; L79-Y83 WeakPolarHBondContact O-CB 3.19Å; L79-Y83 PolarHBondContact O-N 3.33Å; L79-V88 HydrophobicContact CB-CG1 4.42Å; L79-V88 HydrophobicContact CB-CG2 3.87Å; L79-M91 HydrophobicContact CD2-CE 3.58Å; L79-F126 HydrophobicContact CD2-CZ 4.35Å
80	V	82.7	Confident	87.4	Confident	1 Å²	1	44 Å²	44	1%	0.006	24%	0.236	C	C	.	.	H	α-helix	trans	-65.3	-38.3	176.4	165.2	0	0	0	0	111.4	S76 S77 V78 T82 G84 C85 V88 P130 T133	S76-V80 WeakPolarHBondContact O-CB 3.47Å; S76-V80 WeakPolarHBondContact O-CG2 3.21Å; S76-V80 PolarHBondContact O-N 3.23Å; S77-V80 PolarHBondContact O-N 3.4Å; V78-V80 VanDerWaalsContact C-N 3.31Å; V78-V80 PolarHBondContact O-N 3Å; V80-T82 VanDerWaalsContact C-N 3.31Å; V80-G84 CarbonylContact O-C 3.49Å; V80-G84 WeakPolarHBondContact O-CA 3.34Å; V80-G84 PolarHBondContact O-N 3.23Å; V80-C85 HydrophobicContact CG1-CB 4.45Å; V80-C85 WeakPolarHBondContact CG1-SG 3.37Å; V80-V88 HydrophobicContact CG2-CB 4.16Å; V80-V88 HydrophobicContact CG2-CG1 4.11Å; V80-V88 HydrophobicContact CG2-CG2 4.19Å; V80-P130 HydrophobicContact CG2-CB 3.63Å; V80-P130 HydrophobicContact CG2-CG 3.47Å; V80-P130 VanDerWaalsContact CG2-CG 3.47Å; V80-T133 HydrophobicContact CG1-CG2 4.38Å
81	N	79.3	Confident	87.7	Confident	65 Å²	65	46.6 Å²	46.6	35%	0.348	25%	0.25	S	S	.	.	H	α-helix	trans	-71	-27.8	178.6	-69.8	-32.6	0	0	0	112.4	S77 V78 L79 F233	S77-N81 VanDerWaalsContact O-CG 3.28Å; S77-N81 PolarHBondContact O-N 3.07Å; S77-N81 PolarHBondContact O-ND2 3.47Å; S77-N81 VanDerWaalsContact O-ND2 3.1Å; V78-N81 PolarHBondContact O-N 3.22Å; L79-N81 VanDerWaalsContact C-N 3.32Å; N81-F233 WeakPolarHBondContact ND2-CE1 3.37Å; N81-F233 VanDerWaalsContact ND2-CZ 3.3Å; N81-F233 WeakPolarHBondContact ND2-CZ 3.35Å
82	T	81.7	Confident	87.9	Confident	83 Å²	83	44.7 Å²	44.7	51%	0.509	24%	0.235	S	C	.	.	H	α-helix	trans	-89.2	-46.6	178.8	54.6	0	0	0	0	113.2	V78 L79 V80	V78-T82 PolarHBondContact O-N 2.87Å; V78-T82 VanDerWaalsContact O-N 3.11Å; V78-T82 PolarHBondContact O-OG1 3.5Å; L79-T82 WeakPolarHBondContact CA-OG1 3.29Å; L79-T82 PolarHBondContact O-N 3.49Å; L79-T82 PolarHBondContact O-OG1 3.29Å; L79-T82 VanDerWaalsContact O-OG1 3.05Å; V80-T82 VanDerWaalsContact C-N 3.31Å
83	Y	85.1	Confident	88.2	Confident	171 Å²	171	44.7 Å²	44.7	67%	0.671	23%	0.234	S	C	*	.	H	α-helix	trans	-107.4	-9.6	-171.7	-61.3	-70.7	0	0	0	114.1	L79	L79-Y83 WeakPolarHBondContact O-CB 3.19Å; L79-Y83 PolarHBondContact O-N 3.33Å
84	G	85.8	Confident	88.8	Confident	17 Å²	17	47.2 Å²	47.2	18%	0.175	25%	0.248	C	C	.	.			trans	87.2	166.5	-175.4	0	0	0	0	0	113.6	V80 V88	V80-G84 CarbonylContact O-C 3.49Å; V80-G84 WeakPolarHBondContact O-CA 3.34Å; V80-G84 PolarHBondContact O-N 3.23Å; G84-V88 VanDerWaalsContact O-CG2 3.26Å; G84-V88 WeakPolarHBondContact O-CG2 3.46Å
85	C	86.8	Confident	89.4	Confident	10 Å²	10	47.9 Å²	47.9	7%	0.068	25%	0.249	C	C	.	.	H	α-helix	trans	-70.9	-40	-173.1	-55.8	0	0	0	0	113.9	V80 V88 M89 P130 M134	V80-C85 HydrophobicContact CG1-CB 4.45Å; V80-C85 WeakPolarHBondContact CG1-SG 3.37Å; C85-V88 PolarHBondContact O-N 3.11Å; C85-M89 PolarHBondContact O-N 3.26Å; C85-M89 VanDerWaalsContact O-N 3.12Å; C85-P130 HydrophobicContact CB-CB 3.96Å; C85-M134 HydrophobicContact CB-CG 3.54Å; C85-M134 HydrophobicContact CB-SD 3.56Å; C85-M134 VanDerWaalsContact CB-SD 3.56Å; C85-M134 PolarHBondContact SG-SD 2.56Å
86	R	92.6	Very high	89.7	Confident	123 Å²	123	43.8 Å²	43.8	46%	0.464	23%	0.228	S	C	.	.	H	α-helix	trans	-64.6	-50.8	-173.6	173.6	174.7	177.3	-175.7	2	113.5	V88 M89 I90 M195	R86-V88 VanDerWaalsContact C-N 3.3Å; R86-V88 PolarHBondContact O-N 3.36Å; R86-M89 PolarHBondContact O-N 2.9Å; R86-I90 HydrophobicContact CG-CD1 3.88Å; R86-I90 WeakPolarHBondContact O-CG1 3.41Å; R86-I90 PolarHBondContact O-N 2.9Å; R86-I90 VanDerWaalsContact O-N 3.12Å; R86-M195 HydrophobicContact CB-CB 4.48Å
87	P	93.4	Very high	90.1	Very high	72 Å²	72	44.1 Å²	44.1	47%	0.468	23%	0.231	S	C	.	.	H	α-helix	trans	-62.4	-38	178.7	-23.7	35.9	0	0	0	112.7	I90 M91	P87-I90 PolarHBondContact O-N 3.16Å; P87-M91 VanDerWaalsContact O-CB 3.32Å; P87-M91 WeakPolarHBondContact O-CB 3.2Å; P87-M91 PolarHBondContact O-N 3.43Å
88	V	93.9	Very high	90.7	Very high	3 Å²	3	46.8 Å²	46.8	2%	0.018	24%	0.242	C	C	.	.	H	α-helix	trans	-64.8	-43.3	-179.5	178.2	0	0	0	0	111.5	L79 V80 G84 C85 R86 M91 G92 F126 P130	L79-V88 HydrophobicContact CB-CG1 4.42Å; L79-V88 HydrophobicContact CB-CG2 3.87Å; V80-V88 HydrophobicContact CG2-CB 4.16Å; V80-V88 HydrophobicContact CG2-CG1 4.11Å; V80-V88 HydrophobicContact CG2-CG2 4.19Å; G84-V88 VanDerWaalsContact O-CG2 3.26Å; G84-V88 WeakPolarHBondContact O-CG2 3.46Å; C85-V88 PolarHBondContact O-N 3.11Å; R86-V88 VanDerWaalsContact C-N 3.3Å; R86-V88 PolarHBondContact O-N 3.36Å; V88-M91 PolarHBondContact O-N 2.91Å; V88-G92 PolarHBondContact O-N 2.91Å; V88-F126 HydrophobicContact CG1-CB 4.06Å; V88-F126 HydrophobicContact CG1-CG 4.28Å; V88-P130 HydrophobicContact CB-CG 4.3Å; V88-P130 HydrophobicContact CG1-CG 3.86Å
89	M	94.6	Very high	91.4	Very high	0 Å²	0	44.2 Å²	44.2	0%	0	23%	0.226	C	C	.	.	H	α-helix	trans	-66.6	-42.5	175.8	-77	176	61.4	0	0	113.1	S29 C85 R86 M91 G92 G93 N127 P130 M195	S29-M89 VanDerWaalsContact OG-CE 3.29Å; S29-M89 WeakPolarHBondContact OG-CE 3.16Å; C85-M89 PolarHBondContact O-N 3.26Å; C85-M89 VanDerWaalsContact O-N 3.12Å; R86-M89 PolarHBondContact O-N 2.9Å; M89-M91 VanDerWaalsContact C-N 3.3Å; M89-M91 PolarHBondContact O-N 3.41Å; M89-G92 PolarHBondContact O-N 3.12Å; M89-G92 VanDerWaalsContact O-N 3.16Å; M89-G93 PolarHBondContact O-N 3.12Å; M89-N127 PolarHBondContact O-OD1 3.49Å; M89-P130 HydrophobicContact CG-CB 3.68Å; M89-P130 HydrophobicContact CG-CG 3.8Å; M89-P130 HydrophobicContact SD-CB 3.93Å; M89-M195 HydrophobicContact CE-CE 3.7Å; M89-M195 HydrophobicContact CE-CG 3.8Å; M89-M195 HydrophobicContact SD-CB 4.46Å; M89-M195 HydrophobicContact SD-CE 4.15Å; M89-M195 HydrophobicContact SD-CG 3.5Å; M89-M195 WeakPolarHBondContact SD-CG 3.42Å; M89-M195 HydrophobicContact SD-SD 4.37Å
90	I	95.8	Very high	91.9	Very high	60 Å²	60	42.4 Å²	42.4	31%	0.308	22%	0.217	S	C	.	.	H	α-helix	trans	-60.9	-44.7	177	-67.7	170.2	0	0	0	109.9	R86 P87 G92 G93 V94 C189	R86-I90 HydrophobicContact CG-CD1 3.88Å; R86-I90 WeakPolarHBondContact O-CG1 3.41Å; R86-I90 PolarHBondContact O-N 2.9Å; R86-I90 VanDerWaalsContact O-N 3.12Å; P87-I90 PolarHBondContact O-N 3.16Å; I90-G92 VanDerWaalsContact C-N 3.34Å; I90-G92 PolarHBondContact O-N 2.88Å; I90-G93 PolarHBondContact O-N 3.39Å; I90-V94 WeakPolarHBondContact O-CG2 3.23Å; I90-V94 PolarHBondContact O-N 3.03Å; I90-C189 HydrophobicContact CG2-CB 4.42Å; I90-C189 PolarHBondContact O-SG 3.45Å
91	M	95.8	Very high	92.6	Very high	82 Å²	82	45 Å²	45	40%	0.404	23%	0.23	S	C	.	.	H	α-helix	trans	-59.5	-42.9	174.1	-177.2	-178.6	63.6	0	0	111.7	L79 P87 V88 M89 V94 L95 F126	L79-M91 HydrophobicContact CD2-CE 3.58Å; P87-M91 VanDerWaalsContact O-CB 3.32Å; P87-M91 WeakPolarHBondContact O-CB 3.2Å; P87-M91 PolarHBondContact O-N 3.43Å; V88-M91 PolarHBondContact O-N 2.91Å; M89-M91 VanDerWaalsContact C-N 3.3Å; M89-M91 PolarHBondContact O-N 3.41Å; M91-V94 PolarHBondContact O-N 3.17Å; M91-L95 VanDerWaalsContact O-CB 3.23Å; M91-L95 WeakPolarHBondContact O-CB 3.2Å; M91-L95 PolarHBondContact O-N 3.05Å; M91-F126 HydrophobicContact CE-CD2 3.54Å; M91-F126 HydrophobicContact CE-CE2 3.57Å; M91-F126 HydrophobicContact CE-CG 4.43Å; M91-F126 HydrophobicContact CE-CZ 4.48Å
92	G	95	Very high	93.4	Very high	0 Å²	0	44.2 Å²	44.2	0%	0	23%	0.23	C	C	.	.	H	α-helix	trans	-62.6	-41.3	176.6	0	0	0	0	0	113.7	V88 M89 I90 L95 S96 G123	V88-G92 PolarHBondContact O-N 2.91Å; M89-G92 PolarHBondContact O-N 3.12Å; M89-G92 VanDerWaalsContact O-N 3.16Å; I90-G92 VanDerWaalsContact C-N 3.34Å; I90-G92 PolarHBondContact O-N 2.88Å; G92-L95 PolarHBondContact O-N 3.32Å; G92-S96 WeakPolarHBondContact O-CB 3.5Å; G92-S96 PolarHBondContact O-N 3.27Å; G92-S96 PolarHBondContact O-OG 3.03Å; G92-G123 CarbonylContact C-O 3.57Å; G92-G123 WeakPolarHBondContact CA-O 3.22Å; G92-G123 CarbonylContact O-C 3.57Å; G92-G123 VanDerWaalsContact O-CA 3.24Å; G92-G123 WeakPolarHBondContact O-CA 3.46Å
93	G	95.5	Very high	94	Very high	0 Å²	0	40.2 Å²	40.2	0%	0	21%	0.205	C	C	.	.	H	α-helix	trans	-64.2	-44.5	175.5	0	0	0	0	0	112.6	M89 I90 S96 S97 N127 C189	M89-G93 PolarHBondContact O-N 3.12Å; I90-G93 PolarHBondContact O-N 3.39Å; G93-S96 WeakPolarHBondContact CA-OG 3.12Å; G93-S96 PolarHBondContact O-OG 3.1Å; G93-S97 WeakPolarHBondContact O-CB 3.35Å; G93-S97 PolarHBondContact O-N 3.43Å; G93-N127 PolarHBondContact N-ND2 3.12Å; G93-N127 VanDerWaalsContact N-ND2 3.15Å; G93-C189 VanDerWaalsContact C-SG 3.6Å
94	V	97.1	Very high	94.5	Very high	62 Å²	62	32.3 Å²	32.3	38%	0.376	18%	0.175	S	C	.	.	H	α-helix	trans	-63.5	-45	174.7	173.3	0	0	0	0	110.8	I90 M91 S96 S97 I98 L186 C189	I90-V94 WeakPolarHBondContact O-CG2 3.23Å; I90-V94 PolarHBondContact O-N 3.03Å; M91-V94 PolarHBondContact O-N 3.17Å; V94-S96 PolarHBondContact O-N 3.34Å; V94-S97 PolarHBondContact O-N 2.94Å; V94-I98 HydrophobicContact CG1-CD1 3.67Å; V94-I98 HydrophobicContact CG1-CG1 4.32Å; V94-I98 VanDerWaalsContact O-CG1 3.3Å; V94-I98 WeakPolarHBondContact O-CG1 3.12Å; V94-I98 PolarHBondContact O-N 2.84Å; V94-L186 HydrophobicContact CG2-CD1 4.26Å; V94-C189 PolarHBondContact N-SG 3.27Å; V94-C189 VanDerWaalsContact N-SG 3.45Å
95	L	96.4	Very high	94.9	Very high	50 Å²	50	38.5 Å²	38.5	26%	0.262	20%	0.197	S	C	.	.	H	α-helix	trans	-62.6	-45.4	-178.9	-171.2	65.9	0	0	0	111.7	M91 G92 I98 G99 I119 L122 F126	M91-L95 VanDerWaalsContact O-CB 3.23Å; M91-L95 WeakPolarHBondContact O-CB 3.2Å; M91-L95 PolarHBondContact O-N 3.05Å; G92-L95 PolarHBondContact O-N 3.32Å; L95-I98 PolarHBondContact O-N 3.04Å; L95-G99 PolarHBondContact O-N 3.08Å; L95-I119 HydrophobicContact CD1-CG2 3.75Å; L95-I119 HydrophobicContact CG-CG2 3.93Å; L95-I119 VanDerWaalsContact O-CG2 3.3Å; L95-I119 WeakPolarHBondContact O-CG2 3.26Å; L95-L122 HydrophobicContact CD2-CB 3.87Å; L95-F126 HydrophobicContact CD2-CD2 4.42Å; L95-F126 HydrophobicContact CD2-CE2 4.4Å
96	S	95.4	Very high	95.2	Very high	0 Å²	0	38.3 Å²	38.3	0%	0	20%	0.196	C	C	.	.	H	α-helix	trans	-65.3	-40.1	176.4	52.1	0	0	0	0	112.5	G92 G93 V94 G99 L100	G92-S96 WeakPolarHBondContact O-CB 3.5Å; G92-S96 PolarHBondContact O-N 3.27Å; G92-S96 PolarHBondContact O-OG 3.03Å; G93-S96 WeakPolarHBondContact CA-OG 3.12Å; G93-S96 PolarHBondContact O-OG 3.1Å; V94-S96 PolarHBondContact O-N 3.34Å; S96-G99 PolarHBondContact O-N 3.11Å; S96-L100 WeakPolarHBondContact O-CD1 3.4Å; S96-L100 PolarHBondContact O-N 2.61Å; S96-L100 VanDerWaalsContact O-N 3.12Å
97	S	96.2	Very high	95.2	Very high	7 Å²	7	37.7 Å²	37.7	5%	0.049	20%	0.202	C	C	.	.	H	α-helix	trans	-61.1	-46.1	172.9	178.3	0	0	0	0	112.1	G93 V94 G99 L100 I101 G182	G93-S97 WeakPolarHBondContact O-CB 3.35Å; G93-S97 PolarHBondContact O-N 3.43Å; V94-S97 PolarHBondContact O-N 2.94Å; S97-G99 VanDerWaalsContact C-N 3.31Å; S97-G99 PolarHBondContact O-N 3.37Å; S97-L100 PolarHBondContact O-N 2.78Å; S97-I101 WeakPolarHBondContact O-CB 3.11Å; S97-I101 WeakPolarHBondContact O-CG1 3.19Å; S97-I101 PolarHBondContact O-N 3.37Å; S97-I101 WeakPolarHBondContact OG-CD1 3.34Å; S97-G182 WeakPolarHBondContact CB-O 3.29Å; S97-G182 PolarHBondContact OG-O 3.49Å; S97-G182 VanDerWaalsContact OG-O 3.05Å
98	I	96.8	Very high	95.1	Very high	83 Å²	83	36.5 Å²	36.5	43%	0.426	20%	0.195	S	C	.	.	H	α-helix	trans	-61.5	-42.8	176.7	-69.9	168.3	0	0	0	110.2	V94 L95 L100 I101 S102	V94-I98 HydrophobicContact CG1-CD1 3.67Å; V94-I98 HydrophobicContact CG1-CG1 4.32Å; V94-I98 VanDerWaalsContact O-CG1 3.3Å; V94-I98 WeakPolarHBondContact O-CG1 3.12Å; V94-I98 PolarHBondContact O-N 2.84Å; L95-I98 PolarHBondContact O-N 3.04Å; I98-L100 VanDerWaalsContact C-N 3.34Å; I98-L100 PolarHBondContact O-N 2.85Å; I98-I101 PolarHBondContact O-N 3.11Å; I98-S102 VanDerWaalsContact O-CB 3.25Å; I98-S102 WeakPolarHBondContact O-CB 3.17Å; I98-S102 PolarHBondContact O-N 3.25Å; I98-S102 PolarHBondContact O-OG 2.97Å
99	G	96.1	Very high	95	Very high	0 Å²	0	37.1 Å²	37.1	0%	0	20%	0.199	C	C	.	.	H	α-helix	trans	-54.4	-48.1	176.6	0	0	0	0	0	112.5	L95 S96 S97 A103 C115	L95-G99 PolarHBondContact O-N 3.08Å; S96-G99 PolarHBondContact O-N 3.11Å; S97-G99 VanDerWaalsContact C-N 3.31Å; S97-G99 PolarHBondContact O-N 3.37Å; G99-A103 WeakPolarHBondContact O-CB 3.48Å; G99-A103 PolarHBondContact O-N 2.91Å; G99-C115 CarbonylContact C-O 3.59Å; G99-C115 VanDerWaalsContact CA-O 3.26Å; G99-C115 WeakPolarHBondContact CA-O 3.44Å; G99-C115 WeakPolarHBondContact O-CB 3.01Å
100	L	95.1	Very high	94.9	Very high	1 Å²	1	41.5 Å²	41.5	1%	0.005	23%	0.226	C	C	.	.	H	α-helix	trans	-73.5	-41.1	179.3	-91.5	74.1	0	0	0	113.9	F36 S96 S97 I98 S102 A103 S104 L181 L185	F36-L100 HydrophobicContact CE1-CD1 3.87Å; F36-L100 HydrophobicContact CE1-CD2 4.05Å; F36-L100 HydrophobicContact CE1-CG 4.3Å; F36-L100 HydrophobicContact CE2-CD2 3.79Å; F36-L100 HydrophobicContact CZ-CD1 3.99Å; F36-L100 HydrophobicContact CZ-CD2 3.27Å; F36-L100 HydrophobicContact CZ-CG 3.96Å; S96-L100 WeakPolarHBondContact O-CD1 3.4Å; S96-L100 PolarHBondContact O-N 2.61Å; S96-L100 VanDerWaalsContact O-N 3.12Å; S97-L100 PolarHBondContact O-N 2.78Å; I98-L100 VanDerWaalsContact C-N 3.34Å; I98-L100 PolarHBondContact O-N 2.85Å; L100-S102 VanDerWaalsContact C-N 3.33Å; L100-A103 WeakPolarHBondContact O-CB 3.24Å; L100-A103 PolarHBondContact O-N 3.17Å; L100-A103 VanDerWaalsContact O-N 3.16Å; L100-S104 PolarHBondContact O-N 2.87Å; L100-L181 HydrophobicContact CD2-CB 3.54Å; L100-L185 HydrophobicContact CD1-CD1 3.48Å; L100-L185 VanDerWaalsContact CD1-CD1 3.48Å; L100-L185 HydrophobicContact CD2-CD1 3.42Å; L100-L185 VanDerWaalsContact CD2-CD1 3.42Å; L100-L185 HydrophobicContact CG-CD1 4.01Å
101	I	96.5	Very high	94.9	Very high	56 Å²	56	42.8 Å²	42.8	29%	0.287	23%	0.231	S	C	.	.	H	α-helix	trans	-62.7	-45.8	178.9	-68	169.4	0	0	0	109.2	S97 I98 A103 S104 F105 L179	S97-I101 WeakPolarHBondContact O-CB 3.11Å; S97-I101 WeakPolarHBondContact O-CG1 3.19Å; S97-I101 PolarHBondContact O-N 3.37Å; S97-I101 WeakPolarHBondContact OG-CD1 3.34Å; I98-I101 PolarHBondContact O-N 3.11Å; I101-A103 VanDerWaalsContact C-N 3.29Å; I101-A103 PolarHBondContact O-N 3.01Å; I101-S104 WeakPolarHBondContact O-CB 3.37Å; I101-S104 PolarHBondContact O-N 3.21Å; I101-S104 VanDerWaalsContact O-N 3.13Å; I101-S104 PolarHBondContact O-OG 3.36Å; I101-F105 HydrophobicContact CG2-CE2 4.24Å; I101-F105 VanDerWaalsContact O-CD2 3.26Å; I101-F105 WeakPolarHBondContact O-CD2 3.23Å; I101-L179 HydrophobicContact CB-CD1 4.4Å; I101-L179 HydrophobicContact CG1-CD1 4.16Å; I101-L179 HydrophobicContact CG2-CD1 3.82Å
102	S	95.6	Very high	94.8	Very high	48 Å²	48	38.9 Å²	38.9	34%	0.336	21%	0.211	S	C	.	.	H	α-helix	trans	-61.3	-38.5	174.1	-64	0	0	0	0	112	I98 L100 S104 F105 C106	I98-S102 VanDerWaalsContact O-CB 3.25Å; I98-S102 WeakPolarHBondContact O-CB 3.17Å; I98-S102 PolarHBondContact O-N 3.25Å; I98-S102 PolarHBondContact O-OG 2.97Å; L100-S102 VanDerWaalsContact C-N 3.33Å; S102-S104 PolarHBondContact O-N 3.35Å; S102-F105 PolarHBondContact O-N 2.84Å; S102-C106 PolarHBondContact O-SG 3.34Å
103	A	95.1	Very high	94.8	Very high	0 Å²	0	41 Å²	41	0%	0	22%	0.219	C	C	.	.	H	α-helix	trans	-59.6	-27.8	176.3	0	0	0	0	0	113.5	G99 L100 I101 F105 C106 L112 C115 I116 F178	G99-A103 WeakPolarHBondContact O-CB 3.48Å; G99-A103 PolarHBondContact O-N 2.91Å; L100-A103 WeakPolarHBondContact O-CB 3.24Å; L100-A103 PolarHBondContact O-N 3.17Å; L100-A103 VanDerWaalsContact O-N 3.16Å; I101-A103 VanDerWaalsContact C-N 3.29Å; I101-A103 PolarHBondContact O-N 3.01Å; A103-F105 PolarHBondContact O-N 3.42Å; A103-C106 PolarHBondContact O-N 3.48Å; A103-L112 HydrophobicContact CB-CD2 3.94Å; A103-C115 HydrophobicContact CB-CB 3.95Å; A103-I116 HydrophobicContact CB-CD1 3.84Å; A103-I116 HydrophobicContact CB-CG1 3.49Å; A103-I116 VanDerWaalsContact CB-CG1 3.49Å; A103-F178 HydrophobicContact CB-CD2 4.12Å
104	S	95.6	Very high	94.9	Very high	5 Å²	5	44.3 Å²	44.3	4%	0.035	24%	0.24	C	C	.	.	T	Hydrogen-bonded Turn	trans	-66.2	-21.5	177	75.4	0	0	0	0	113.9	L100 I101 S102 R175	L100-S104 PolarHBondContact O-N 2.87Å; I101-S104 WeakPolarHBondContact O-CB 3.37Å; I101-S104 PolarHBondContact O-N 3.21Å; I101-S104 VanDerWaalsContact O-N 3.13Å; I101-S104 PolarHBondContact O-OG 3.36Å; S102-S104 PolarHBondContact O-N 3.35Å; S104-R175 VanDerWaalsContact CB-O 3.23Å; S104-R175 WeakPolarHBondContact CB-O 3.45Å; S104-R175 WeakPolarHBondContact O-CD 3.2Å; S104-R175 WeakPolarHBondContact O-CG 3.43Å
105	F	94.6	Very high	94.8	Very high	146 Å²	146	42.1 Å²	42.1	64%	0.64	23%	0.227	S	C	*	.	T	Hydrogen-bonded Turn	trans	-100.8	-3.2	179.7	-59.4	-75.7	0	0	0	113.4	I101 S102 A103 N107	I101-F105 HydrophobicContact CG2-CE2 4.24Å; I101-F105 VanDerWaalsContact O-CD2 3.26Å; I101-F105 WeakPolarHBondContact O-CD2 3.23Å; S102-F105 PolarHBondContact O-N 2.84Å; A103-F105 PolarHBondContact O-N 3.42Å; F105-N107 PolarHBondContact O-ND2 3Å
106	C	93.3	Very high	94.7	Very high	7 Å²	7	39.8 Å²	39.8	5%	0.047	22%	0.215	C	C	.	.			trans	-67.5	144.7	-178.9	-68.7	0	0	0	0	112.2	S102 A103 E111 L112 W174 R175	S102-C106 PolarHBondContact O-SG 3.34Å; A103-C106 PolarHBondContact O-N 3.48Å; C106-E111 VanDerWaalsContact CA-OE2 3.25Å; C106-E111 WeakPolarHBondContact CA-OE2 3.36Å; C106-E111 HydrophobicContact CB-CB 3.87Å; C106-E111 WeakPolarHBondContact CB-OE2 3.26Å; C106-E111 VanDerWaalsContact SG-CB 3.52Å; C106-L112 HydrophobicContact CB-CD2 3.75Å; C106-L112 HydrophobicContact CB-CG 4.16Å; C106-W174 WeakPolarHBondContact O-CH2 3.27Å; C106-R175 PolarHBondContact O-NH2 3.37Å
107	N	91.8	Very high	94.7	Very high	110 Å²	110	39.8 Å²	39.8	59%	0.588	22%	0.215	S	C	*	.			trans	-122.5	4.7	177.5	-61.5	-53.1	0	0	0	112.5	F51 F105 E111 R175	F51-N107 VanDerWaalsContact CE1-O 3.29Å; F51-N107 WeakPolarHBondContact CE1-O 3.47Å; F105-N107 PolarHBondContact O-ND2 3Å; N107-E111 PolarHBondContact N-OE2 3.46Å; N107-R175 PolarHBondContact OD1-NH2 3.26Å
108	S	91.8	Very high	94.7	Very high	46 Å²	46	43.3 Å²	43.3	32%	0.322	23%	0.233	S	C	.	.	S	Bend	trans	-136	147.8	174.3	175.2	0	0	0	0	111.6	V110 E111 L112	S108-V110 PolarHBondContact O-N 3.26Å; S108-V110 PolarHBondContact OG-N 3.43Å; S108-E111 PolarHBondContact N-OE2 3.37Å; S108-E111 WeakPolarHBondContact O-CB 3.4Å; S108-E111 PolarHBondContact O-N 2.9Å; S108-E111 VanDerWaalsContact O-N 3.17Å; S108-L112 PolarHBondContact O-N 2.95Å
109	V	90.8	Very high	94.7	Very high	17 Å²	17	41.6 Å²	41.6	10%	0.103	22%	0.224	C	C	.	.	H	α-helix	trans	-61.9	-32	175.7	-173.5	0	0	0	0	111.3	F51 C53 E111 L112 Y113	F51-V109 HydrophobicContact CB-CG2 3.68Å; F51-V109 HydrophobicContact CD1-CG2 4.49Å; F51-V109 HydrophobicContact CD2-CG2 4.32Å; F51-V109 HydrophobicContact CG-CG2 3.93Å; C53-V109 HydrophobicContact CB-CG2 4.21Å; V109-E111 VanDerWaalsContact C-N 3.34Å; V109-E111 PolarHBondContact O-N 3.37Å; V109-L112 WeakPolarHBondContact O-CB 3.48Å; V109-L112 PolarHBondContact O-N 2.9Å; V109-Y113 HydrophobicContact CG1-CD1 4.43Å; V109-Y113 HydrophobicContact CG1-CE1 3.61Å; V109-Y113 HydrophobicContact CG1-CE2 4.48Å; V109-Y113 WeakPolarHBondContact O-CD1 3.4Å; V109-Y113 PolarHBondContact O-N 3.46Å
110	V	92.8	Very high	94.6	Very high	91 Å²	91	41.6 Å²	41.6	55%	0.552	22%	0.224	S	C	*	.	H	α-helix	trans	-66.7	-37.9	177.6	-178.2	0	0	0	0	111.2	S108 L112 Y113 V114	S108-V110 PolarHBondContact O-N 3.26Å; S108-V110 PolarHBondContact OG-N 3.43Å; V110-L112 VanDerWaalsContact C-N 3.29Å; V110-L112 PolarHBondContact O-N 2.91Å; V110-Y113 HydrophobicContact CG2-CE2 4.5Å; V110-Y113 WeakPolarHBondContact O-CB 3.27Å; V110-Y113 PolarHBondContact O-N 2.94Å; V110-V114 PolarHBondContact O-N 2.86Å
111	E	94.9	Very high	94.6	Very high	88 Å²	88	41.6 Å²	41.6	41%	0.411	22%	0.224	S	C	.	.	H	α-helix	trans	-64.7	-38	174.4	-61.3	171.5	168.8	0	0	110.7	C106 N107 S108 V109 Y113 V114 C115	C106-E111 VanDerWaalsContact CA-OE2 3.25Å; C106-E111 WeakPolarHBondContact CA-OE2 3.36Å; C106-E111 HydrophobicContact CB-CB 3.87Å; C106-E111 WeakPolarHBondContact CB-OE2 3.26Å; C106-E111 VanDerWaalsContact SG-CB 3.52Å; N107-E111 PolarHBondContact N-OE2 3.46Å; S108-E111 PolarHBondContact N-OE2 3.37Å; S108-E111 WeakPolarHBondContact O-CB 3.4Å; S108-E111 PolarHBondContact O-N 2.9Å; S108-E111 VanDerWaalsContact O-N 3.17Å; V109-E111 VanDerWaalsContact C-N 3.34Å; V109-E111 PolarHBondContact O-N 3.37Å; E111-Y113 VanDerWaalsContact C-N 3.33Å; E111-Y113 PolarHBondContact O-N 3.48Å; E111-V114 PolarHBondContact O-N 3.36Å; E111-V114 VanDerWaalsContact O-N 3.15Å; E111-C115 WeakPolarHBondContact O-CB 3.39Å; E111-C115 PolarHBondContact O-N 2.93Å; E111-C115 PolarHBondContact O-SG 2.9Å
112	L	94.4	Very high	94.6	Very high	0 Å²	0	41.3 Å²	41.3	0%	0	22%	0.223	C	C	.	.	H	α-helix	trans	-63.3	-35.2	174	-64.3	176.7	0	0	0	112.6	I47 F51 I61 A103 C106 S108 V109 V110 V114 I116 G117 W174 F178	I47-L112 HydrophobicContact CG2-CD1 4.28Å; F51-L112 HydrophobicContact CE2-CD1 4.18Å; I61-L112 HydrophobicContact CD1-CB 4.22Å; I61-L112 HydrophobicContact CD1-CD1 4.31Å; A103-L112 HydrophobicContact CB-CD2 3.94Å; C106-L112 HydrophobicContact CB-CD2 3.75Å; C106-L112 HydrophobicContact CB-CG 4.16Å; S108-L112 PolarHBondContact O-N 2.95Å; V109-L112 WeakPolarHBondContact O-CB 3.48Å; V109-L112 PolarHBondContact O-N 2.9Å; V110-L112 VanDerWaalsContact C-N 3.29Å; V110-L112 PolarHBondContact O-N 2.91Å; L112-V114 VanDerWaalsContact C-N 3.29Å; L112-V114 PolarHBondContact O-N 3.34Å; L112-I116 HydrophobicContact CB-CD1 4.49Å; L112-I116 HydrophobicContact CD2-CD1 3.94Å; L112-I116 WeakPolarHBondContact O-CB 3.31Å; L112-I116 PolarHBondContact O-N 3.21Å; L112-G117 PolarHBondContact O-N 3.2Å; L112-W174 HydrophobicContact CD2-CZ3 4.31Å; L112-F178 HydrophobicContact CD2-CE2 4.48Å
113	Y	95.3	Very high	94.6	Very high	43 Å²	43	39 Å²	39	17%	0.169	21%	0.207	C	C	.	.	I	π-helix	trans	-60.7	-40.1	173	-59.9	-24.6	0	0	0	112	Q57 W60 I61 I64 V109 V110 E111 G117 L118	Q57-Y113 WeakPolarHBondContact CA-OH 3.46Å; Q57-Y113 VanDerWaalsContact O-CE1 3.29Å; Q57-Y113 WeakPolarHBondContact O-CE1 3.05Å; Q57-Y113 PolarHBondContact O-OH 3.45Å; W60-Y113 HydrophobicContact CB-CD1 4.17Å; W60-Y113 HydrophobicContact CB-CE1 3.6Å; I61-Y113 HydrophobicContact CG1-CD1 3.65Å; I61-Y113 HydrophobicContact CG1-CE1 3.65Å; I64-Y113 HydrophobicContact CD1-CD1 4.18Å; I64-Y113 HydrophobicContact CD1-CD2 4.43Å; I64-Y113 HydrophobicContact CD1-CG 3.93Å; V109-Y113 HydrophobicContact CG1-CD1 4.43Å; V109-Y113 HydrophobicContact CG1-CE1 3.61Å; V109-Y113 HydrophobicContact CG1-CE2 4.48Å; V109-Y113 WeakPolarHBondContact O-CD1 3.4Å; V109-Y113 PolarHBondContact O-N 3.46Å; V110-Y113 HydrophobicContact CG2-CE2 4.5Å; V110-Y113 WeakPolarHBondContact O-CB 3.27Å; V110-Y113 PolarHBondContact O-N 2.94Å; E111-Y113 VanDerWaalsContact C-N 3.33Å; E111-Y113 PolarHBondContact O-N 3.48Å; Y113-G117 CarbonylContact O-C 3.52Å; Y113-G117 WeakPolarHBondContact O-CA 3.37Å; Y113-G117 PolarHBondContact O-N 3.07Å; Y113-G117 VanDerWaalsContact O-N 3.11Å; Y113-L118 PolarHBondContact O-N 3.49Å
114	V	96.5	Very high	94.6	Very high	71 Å²	71	39.1 Å²	39.1	43%	0.43	21%	0.207	S	C	.	.	I	π-helix	trans	-74	-50.1	-179.9	178.4	0	0	0	0	110.5	V110 E111 L112 L118 I119	V110-V114 PolarHBondContact O-N 2.86Å; E111-V114 PolarHBondContact O-N 3.36Å; E111-V114 VanDerWaalsContact O-N 3.15Å; L112-V114 VanDerWaalsContact C-N 3.29Å; L112-V114 PolarHBondContact O-N 3.34Å; V114-L118 WeakPolarHBondContact O-CB 3.28Å; V114-L118 PolarHBondContact O-N 2.96Å; V114-I119 HydrophobicContact CG1-CD1 4.33Å; V114-I119 WeakPolarHBondContact O-CG1 3.42Å; V114-I119 PolarHBondContact O-N 2.91Å
115	C	96.4	Very high	94.5	Very high	16 Å²	16	38.9 Å²	38.9	11%	0.108	21%	0.206	C	C	.	.	I	π-helix	trans	-70.3	-52.1	-174.6	-70.5	0	0	0	0	112.9	G99 A103 E111 I119 G120	G99-C115 CarbonylContact C-O 3.59Å; G99-C115 VanDerWaalsContact CA-O 3.26Å; G99-C115 WeakPolarHBondContact CA-O 3.44Å; G99-C115 WeakPolarHBondContact O-CB 3.01Å; A103-C115 HydrophobicContact CB-CB 3.95Å; E111-C115 WeakPolarHBondContact O-CB 3.39Å; E111-C115 PolarHBondContact O-N 2.93Å; E111-C115 PolarHBondContact O-SG 2.9Å; C115-I119 WeakPolarHBondContact O-CB 3.24Å; C115-G120 PolarHBondContact O-N 3.29Å; C115-G120 VanDerWaalsContact O-N 3.08Å
116	I	94.5	Very high	94.5	Very high	1 Å²	1	32.8 Å²	32.8	1%	0.005	18%	0.179	C	C	.	.	I	π-helix	trans	-84.4	-48.6	-177.8	-58.2	176.5	0	0	0	110.1	I40 I61 M65 A103 L112 G120 G121 F178	I40-I116 HydrophobicContact CD1-CD1 3.92Å; I40-I116 HydrophobicContact CD1-CG2 3.71Å; I61-I116 HydrophobicContact CG2-CB 4.05Å; I61-I116 HydrophobicContact CG2-CD1 4.37Å; I61-I116 HydrophobicContact CG2-CG2 3.82Å; M65-I116 HydrophobicContact CE-CG2 4.28Å; M65-I116 HydrophobicContact SD-CG2 3.71Å; M65-I116 VanDerWaalsContact SD-O 3.34Å; A103-I116 HydrophobicContact CB-CD1 3.84Å; A103-I116 HydrophobicContact CB-CG1 3.49Å; A103-I116 VanDerWaalsContact CB-CG1 3.49Å; L112-I116 HydrophobicContact CB-CD1 4.49Å; L112-I116 HydrophobicContact CD2-CD1 3.94Å; L112-I116 WeakPolarHBondContact O-CB 3.31Å; L112-I116 PolarHBondContact O-N 3.21Å; I116-G120 VanDerWaalsContact O-CA 3.27Å; I116-G120 WeakPolarHBondContact O-CA 3.44Å; I116-G120 PolarHBondContact O-N 3.28Å; I116-G121 PolarHBondContact O-N 3.42Å; I116-F178 HydrophobicContact CD1-CD2 4.29Å; I116-F178 HydrophobicContact CD1-CE2 3.7Å; I116-F178 HydrophobicContact CD1-CZ 3.95Å
117	G	94.1	Very high	94.5	Very high	0 Å²	0	32.4 Å²	32.4	0%	0	18%	0.177	C	C	.	.	I	π-helix	trans	-67.1	-65.3	-175.7	0	0	0	0	0	112.5	M65 L112 Y113 G121	M65-G117 WeakPolarHBondContact CA-O 3.48Å; L112-G117 PolarHBondContact O-N 3.2Å; Y113-G117 CarbonylContact O-C 3.52Å; Y113-G117 WeakPolarHBondContact O-CA 3.37Å; Y113-G117 PolarHBondContact O-N 3.07Å; Y113-G117 VanDerWaalsContact O-N 3.11Å; G117-G121 VanDerWaalsContact O-CA 3.3Å; G117-G121 WeakPolarHBondContact O-CA 3.2Å; G117-G121 PolarHBondContact O-N 2.89Å
118	L	96	Very high	94.5	Very high	81 Å²	81	28 Å²	28	42%	0.424	15%	0.153	S	C	.	.	I	π-helix	trans	-76.3	-57.3	-173	-174.3	66.3	0	0	0	112.6	V68 Y113 V114 L122	V68-L118 HydrophobicContact CG1-CD1 4.22Å; V68-L118 HydrophobicContact CG2-CD1 3.9Å; Y113-L118 PolarHBondContact O-N 3.49Å; V114-L118 WeakPolarHBondContact O-CB 3.28Å; V114-L118 PolarHBondContact O-N 2.96Å; L118-L122 HydrophobicContact CD1-CD1 4.35Å; L118-L122 HydrophobicContact CG-CD1 4.47Å; L118-L122 WeakPolarHBondContact O-CB 3.31Å; L118-L122 WeakPolarHBondContact O-CG 3.49Å; L118-L122 PolarHBondContact O-N 3.26Å
119	I	96.6	Very high	94.2	Very high	46 Å²	46	28.1 Å²	28.1	24%	0.236	15%	0.148	C	C	.	.	I	π-helix	trans	-68.1	-49.5	-175.8	-64	172	0	0	0	110.2	L95 V114 C115 L122 G123	L95-I119 HydrophobicContact CD1-CG2 3.75Å; L95-I119 HydrophobicContact CG-CG2 3.93Å; L95-I119 VanDerWaalsContact O-CG2 3.3Å; L95-I119 WeakPolarHBondContact O-CG2 3.26Å; V114-I119 HydrophobicContact CG1-CD1 4.33Å; V114-I119 WeakPolarHBondContact O-CG1 3.42Å; V114-I119 PolarHBondContact O-N 2.91Å; C115-I119 WeakPolarHBondContact O-CB 3.24Å; I119-L122 PolarHBondContact O-N 3.18Å; I119-G123 PolarHBondContact O-N 2.93Å
120	G	95.1	Very high	94.1	Very high	1 Å²	1	27.3 Å²	27.3	1%	0.01	14%	0.143	C	C	.	.	I	π-helix	trans	-58.7	-49.4	174.5	0	0	0	0	0	112.6	C115 I116 L122 G123 L124	C115-G120 PolarHBondContact O-N 3.29Å; C115-G120 VanDerWaalsContact O-N 3.08Å; I116-G120 VanDerWaalsContact O-CA 3.27Å; I116-G120 WeakPolarHBondContact O-CA 3.44Å; I116-G120 PolarHBondContact O-N 3.28Å; G120-L122 PolarHBondContact O-N 3.34Å; G120-G123 PolarHBondContact O-N 3.43Å; G120-G123 VanDerWaalsContact O-N 3.17Å; G120-L124 WeakPolarHBondContact O-CG 3.49Å; G120-L124 PolarHBondContact O-N 3.36Å
121	G	95.3	Very high	94	Very high	0 Å²	0	23 Å²	23	0%	0	12%	0.117	C	C	.	.	H	α-helix	trans	-58.8	-44.3	178.6	0	0	0	0	0	113.8	I116 G117 L124 A125	I116-G121 PolarHBondContact O-N 3.42Å; G117-G121 VanDerWaalsContact O-CA 3.3Å; G117-G121 WeakPolarHBondContact O-CA 3.2Å; G117-G121 PolarHBondContact O-N 2.89Å; G121-L124 PolarHBondContact O-N 3.16Å; G121-A125 PolarHBondContact O-N 3.45Å
122	L	95.6	Very high	93.6	Very high	50 Å²	50	21.1 Å²	21.1	26%	0.262	11%	0.11	S	C	.	.	H	α-helix	trans	-63.4	-42.3	175.1	-77	174.7	0	0	0	111.3	V68 L95 L118 I119 G120 L124 A125 F126	V68-L122 HydrophobicContact CG1-CB 4.27Å; V68-L122 HydrophobicContact CG1-CD2 3.73Å; V68-L122 HydrophobicContact CG1-CG 3.54Å; L95-L122 HydrophobicContact CD2-CB 3.87Å; L118-L122 HydrophobicContact CD1-CD1 4.35Å; L118-L122 HydrophobicContact CG-CD1 4.47Å; L118-L122 WeakPolarHBondContact O-CB 3.31Å; L118-L122 WeakPolarHBondContact O-CG 3.49Å; L118-L122 PolarHBondContact O-N 3.26Å; I119-L122 PolarHBondContact O-N 3.18Å; G120-L122 PolarHBondContact O-N 3.34Å; L122-L124 VanDerWaalsContact C-N 3.33Å; L122-L124 PolarHBondContact O-N 3.44Å; L122-A125 WeakPolarHBondContact O-CB 3.01Å; L122-A125 PolarHBondContact O-N 3.31Å; L122-F126 WeakPolarHBondContact O-CG 3.24Å; L122-F126 PolarHBondContact O-N 3.4Å
123	G	95.7	Very high	93.1	Very high	0 Å²	0	22.9 Å²	22.9	0%	0	12%	0.121	C	C	.	.	H	α-helix	trans	-61.2	-40.5	176.6	0	0	0	0	0	112.8	G92 I119 G120 F126 N127	G92-G123 CarbonylContact C-O 3.57Å; G92-G123 WeakPolarHBondContact CA-O 3.22Å; G92-G123 CarbonylContact O-C 3.57Å; G92-G123 VanDerWaalsContact O-CA 3.24Å; G92-G123 WeakPolarHBondContact O-CA 3.46Å; I119-G123 PolarHBondContact O-N 2.93Å; G120-G123 PolarHBondContact O-N 3.43Å; G120-G123 VanDerWaalsContact O-N 3.17Å; G123-F126 PolarHBondContact O-N 2.89Å; G123-N127 PolarHBondContact O-N 3.16Å; G123-N127 PolarHBondContact O-ND2 3.35Å
124	L	95.1	Very high	92.6	Very high	2 Å²	2	21 Å²	21	1%	0.01	11%	0.114	C	C	.	.	H	α-helix	trans	-70.7	-34	175.6	-65.5	-179.3	0	0	0	112.5	S33 F36 P37 M65 M69 G120 G121 L122 N127 L128 L185	S33-L124 PolarHBondContact OG-O 3.28Å; F36-L124 HydrophobicContact CB-CD1 4.32Å; F36-L124 HydrophobicContact CD1-CD1 4.39Å; P37-L124 HydrophobicContact CG-CD1 4.45Å; M65-L124 HydrophobicContact CG-CD1 4.42Å; M65-L124 HydrophobicContact SD-CD1 4.21Å; M69-L124 HydrophobicContact CG-CB 4.32Å; M69-L124 HydrophobicContact SD-CB 4.22Å; G120-L124 WeakPolarHBondContact O-CG 3.49Å; G120-L124 PolarHBondContact O-N 3.36Å; G121-L124 PolarHBondContact O-N 3.16Å; L122-L124 VanDerWaalsContact C-N 3.33Å; L122-L124 PolarHBondContact O-N 3.44Å; L124-N127 PolarHBondContact O-N 3.45Å; L124-L128 WeakPolarHBondContact O-CB 3.46Å; L124-L128 PolarHBondContact O-N 3.2Å; L124-L185 HydrophobicContact CD2-CD2 4.05Å
125	A	94.1	Very high	92	Very high	1 Å²	1	17.7 Å²	17.7	1%	0.008	9%	0.093	C	C	.	.	H	α-helix	trans	-61.5	-45.8	173.1	0	0	0	0	0	111.5	M69 G121 L122 N127 L128 Q129	M69-A125 WeakPolarHBondContact O-CB 3.32Å; G121-A125 PolarHBondContact O-N 3.45Å; L122-A125 WeakPolarHBondContact O-CB 3.01Å; L122-A125 PolarHBondContact O-N 3.31Å; A125-N127 PolarHBondContact O-N 3.37Å; A125-L128 PolarHBondContact O-N 3.32Å; A125-Q129 PolarHBondContact O-N 3.03Å; A125-Q129 VanDerWaalsContact O-N 3.12Å
126	F	94.2	Very high	91.2	Very high	17 Å²	17	18 Å²	18	8%	0.075	10%	0.1	C	C	.	.	H	α-helix	trans	-69.4	-14.2	178.4	-66.5	-9	0	0	0	113.3	I75 L79 V88 M91 L95 L122 G123 P130	I75-F126 HydrophobicContact CG2-CE1 3.96Å; I75-F126 HydrophobicContact CG2-CZ 4.14Å; L79-F126 HydrophobicContact CD2-CZ 4.35Å; V88-F126 HydrophobicContact CG1-CB 4.06Å; V88-F126 HydrophobicContact CG1-CG 4.28Å; M91-F126 HydrophobicContact CE-CD2 3.54Å; M91-F126 HydrophobicContact CE-CE2 3.57Å; M91-F126 HydrophobicContact CE-CG 4.43Å; M91-F126 HydrophobicContact CE-CZ 4.48Å; L95-F126 HydrophobicContact CD2-CD2 4.42Å; L95-F126 HydrophobicContact CD2-CE2 4.4Å; L122-F126 WeakPolarHBondContact O-CG 3.24Å; L122-F126 PolarHBondContact O-N 3.4Å; G123-F126 PolarHBondContact O-N 2.89Å; F126-P130 WeakPolarHBondContact O-CD 3.43Å; F126-P130 WeakPolarHBondContact O-CG 3.46Å
127	N	93.9	Very high	90.6	Very high	0 Å²	0	22.7 Å²	22.7	0%	0	12%	0.12	C	C	.	.	H	α-helix	trans	-88.4	-42.1	168.5	-84.7	-65.2	0	0	0	112.6	M89 G93 G123 L124 A125 A131	M89-N127 PolarHBondContact O-OD1 3.49Å; G93-N127 PolarHBondContact N-ND2 3.12Å; G93-N127 VanDerWaalsContact N-ND2 3.15Å; G123-N127 PolarHBondContact O-N 3.16Å; G123-N127 PolarHBondContact O-ND2 3.35Å; L124-N127 PolarHBondContact O-N 3.45Å; A125-N127 PolarHBondContact O-N 3.37Å; N127-A131 WeakPolarHBondContact O-CB 3.5Å
128	L	90.6	Very high	90.2	Very high	16 Å²	16	22.9 Å²	22.9	8%	0.084	12%	0.121	C	C	.	.	H	α-helix	trans	-67.8	-53.2	-173.7	176.9	58.7	0	0	0	112.6	I30 Y34 M69 L124 A125 A131 L132	I30-L128 HydrophobicContact CB-CD1 4.47Å; I30-L128 HydrophobicContact CG1-CD1 3.93Å; I30-L128 HydrophobicContact CG2-CD1 4.37Å; Y34-L128 HydrophobicContact CD2-CD1 4.24Å; Y34-L128 HydrophobicContact CE2-CD1 3.64Å; Y34-L128 HydrophobicContact CE2-CD2 4.03Å; M69-L128 HydrophobicContact CE-CD2 4.29Å; M69-L128 HydrophobicContact CG-CD2 4.31Å; M69-L128 HydrophobicContact SD-CD2 4.21Å; L124-L128 WeakPolarHBondContact O-CB 3.46Å; L124-L128 PolarHBondContact O-N 3.2Å; A125-L128 PolarHBondContact O-N 3.32Å; L128-A131 PolarHBondContact O-N 2.89Å; L128-L132 HydrophobicContact CD1-CD1 4.22Å; L128-L132 HydrophobicContact CG-CD1 4.46Å; L128-L132 PolarHBondContact O-N 3.38Å
129	Q	87.3	Confident	89.4	Confident	49 Å²	49	19.1 Å²	19.1	23%	0.229	10%	0.101	C	C	.	.	H	α-helix	trans	-65.9	-46	-171.5	-177.3	64.9	62.7	0	0	113.1	A125 A131 L132 T133	A125-Q129 PolarHBondContact O-N 3.03Å; A125-Q129 VanDerWaalsContact O-N 3.12Å; Q129-A131 VanDerWaalsContact C-N 3.31Å; Q129-A131 PolarHBondContact O-N 3.44Å; Q129-L132 PolarHBondContact O-N 3.02Å; Q129-T133 PolarHBondContact O-N 3.2Å; Q129-T133 VanDerWaalsContact O-N 3.11Å; Q129-T133 PolarHBondContact O-OG1 3.31Å
130	P	88.8	Confident	88.4	Confident	0 Å²	0	25.1 Å²	25.1	0%	0	12%	0.122	C	C	.	.	H	α-helix	trans	-69.1	-30.7	-179.4	-14.5	29.5	0	0	0	112.4	V80 C85 V88 M89 F126 L132 T133 M134	V80-P130 HydrophobicContact CG2-CB 3.63Å; V80-P130 HydrophobicContact CG2-CG 3.47Å; V80-P130 VanDerWaalsContact CG2-CG 3.47Å; C85-P130 HydrophobicContact CB-CB 3.96Å; V88-P130 HydrophobicContact CB-CG 4.3Å; V88-P130 HydrophobicContact CG1-CG 3.86Å; M89-P130 HydrophobicContact CG-CB 3.68Å; M89-P130 HydrophobicContact CG-CG 3.8Å; M89-P130 HydrophobicContact SD-CB 3.93Å; F126-P130 WeakPolarHBondContact O-CD 3.43Å; F126-P130 WeakPolarHBondContact O-CG 3.46Å; P130-L132 PolarHBondContact O-N 3.45Å; P130-T133 PolarHBondContact O-N 3.46Å; P130-M134 WeakPolarHBondContact O-CB 3.38Å; P130-M134 VanDerWaalsContact O-CG 3.28Å; P130-M134 WeakPolarHBondContact O-CG 3.38Å; P130-M134 PolarHBondContact O-N 3.04Å
131	A	90.2	Very high	87.4	Confident	0 Å²	0	33.7 Å²	33.7	0%	0	16%	0.159	C	C	.	.	H	α-helix	trans	-60	-44.3	174.7	0	0	0	0	0	111.7	S26 I30 N127 L128 Q129 M134 I135	S26-A131 PolarHBondContact OG-O 2.82Å; S26-A131 VanDerWaalsContact OG-O 3.12Å; I30-A131 HydrophobicContact CG1-CB 4.29Å; N127-A131 WeakPolarHBondContact O-CB 3.5Å; L128-A131 PolarHBondContact O-N 2.89Å; Q129-A131 VanDerWaalsContact C-N 3.31Å; Q129-A131 PolarHBondContact O-N 3.44Å; A131-M134 PolarHBondContact O-N 3.19Å; A131-I135 WeakPolarHBondContact O-CG1 3.13Å; A131-I135 PolarHBondContact O-N 3.28Å
132	L	85.3	Confident	86.6	Confident	50 Å²	50	38.1 Å²	38.1	26%	0.262	18%	0.178	S	C	.	.	H	α-helix	trans	-65.7	-42	175	-69.3	172.3	0	0	0	112.2	I30 L128 Q129 P130 M134 G136	I30-L132 HydrophobicContact CD1-CD2 3.86Å; I30-L132 HydrophobicContact CD1-CG 4.37Å; L128-L132 HydrophobicContact CD1-CD1 4.22Å; L128-L132 HydrophobicContact CG-CD1 4.46Å; L128-L132 PolarHBondContact O-N 3.38Å; Q129-L132 PolarHBondContact O-N 3.02Å; P130-L132 PolarHBondContact O-N 3.45Å; L132-M134 VanDerWaalsContact C-N 3.35Å; L132-M134 PolarHBondContact O-N 2.87Å; L132-G136 PolarHBondContact O-N 3.41Å
133	T	84.3	Confident	85.6	Confident	36 Å²	36	41 Å²	41	22%	0.221	19%	0.185	C	C	.	.	H	α-helix	trans	-63.6	-40	177.4	-59	0	0	0	0	111.8	V80 Q129 P130 G136 K137	V80-T133 HydrophobicContact CG1-CG2 4.38Å; Q129-T133 PolarHBondContact O-N 3.2Å; Q129-T133 VanDerWaalsContact O-N 3.11Å; Q129-T133 PolarHBondContact O-OG1 3.31Å; P130-T133 PolarHBondContact O-N 3.46Å; T133-G136 PolarHBondContact O-N 3.18Å; T133-K137 HydrophobicContact CG2-CD 4.44Å; T133-K137 WeakPolarHBondContact O-CG 3.38Å; T133-K137 PolarHBondContact O-N 3.06Å; T133-K137 VanDerWaalsContact O-N 3.11Å
134	M	85.3	Confident	84.6	Confident	5 Å²	5	45.6 Å²	45.6	3%	0.025	22%	0.216	C	C	.	.	H	α-helix	trans	-67.1	-41.6	179.8	-75.3	-58	-70.7	0	0	112.7	V22 C85 P130 A131 L132 G136 K137 Y138 M195 R196	V22-M134 HydrophobicContact CG1-CB 3.98Å; C85-M134 HydrophobicContact CB-CG 3.54Å; C85-M134 HydrophobicContact CB-SD 3.56Å; C85-M134 VanDerWaalsContact CB-SD 3.56Å; C85-M134 PolarHBondContact SG-SD 2.56Å; P130-M134 WeakPolarHBondContact O-CB 3.38Å; P130-M134 VanDerWaalsContact O-CG 3.28Å; P130-M134 WeakPolarHBondContact O-CG 3.38Å; P130-M134 PolarHBondContact O-N 3.04Å; A131-M134 PolarHBondContact O-N 3.19Å; L132-M134 VanDerWaalsContact C-N 3.35Å; L132-M134 PolarHBondContact O-N 2.87Å; M134-G136 VanDerWaalsContact C-N 3.28Å; M134-G136 PolarHBondContact O-N 3.44Å; M134-K137 PolarHBondContact O-N 3.16Å; M134-K137 VanDerWaalsContact O-N 3.11Å; M134-K137 HydrophobicContact SD-CD 4.5Å; M134-Y138 HydrophobicContact CE-CD2 3.94Å; M134-Y138 HydrophobicContact CE-CE2 3.47Å; M134-Y138 VanDerWaalsContact CE-CE2 3.47Å; M134-Y138 WeakPolarHBondContact O-CD2 3.41Å; M134-Y138 PolarHBondContact O-N 3.12Å; M134-M195 HydrophobicContact CB-SD 3.75Å; M134-M195 HydrophobicContact CE-CB 4.13Å; M134-M195 HydrophobicContact CG-CB 4.23Å; M134-M195 HydrophobicContact CG-CG 4.31Å; M134-M195 HydrophobicContact CG-SD 3.83Å; M134-R196 WeakPolarHBondContact CE-O 3.43Å
135	I	84.7	Confident	84	Confident	0 Å²	0	50.2 Å²	50.2	0%	0	24%	0.239	C	C	.	.	H	α-helix	trans	-58	-45.1	173.7	-65.6	162.5	0	0	0	110.3	A131 K137 Y138 F139 A146 N147 A150	A131-I135 WeakPolarHBondContact O-CG1 3.13Å; A131-I135 PolarHBondContact O-N 3.28Å; I135-K137 PolarHBondContact O-N 3.27Å; I135-Y138 PolarHBondContact O-N 3.49Å; I135-F139 HydrophobicContact CG2-CD2 4.32Å; I135-F139 PolarHBondContact O-N 3.27Å; I135-A146 HydrophobicContact CG2-CB 3.63Å; I135-N147 VanDerWaalsContact CG2-OD1 3.23Å; I135-N147 WeakPolarHBondContact CG2-OD1 3.24Å; I135-A150 HydrophobicContact CD1-CB 3.5Å
136	G	78.9	Confident	83.5	Confident	24 Å²	24	50.2 Å²	50.2	25%	0.247	24%	0.239	C	C	.	.	H	α-helix	trans	-65.2	-23.5	178.3	0	0	0	0	0	114.8	L132 T133 M134	L132-G136 PolarHBondContact O-N 3.41Å; T133-G136 PolarHBondContact O-N 3.18Å; M134-G136 VanDerWaalsContact C-N 3.28Å; M134-G136 PolarHBondContact O-N 3.44Å
137	K	82.3	Confident	83	Confident	99 Å²	99	51.6 Å²	51.6	43%	0.43	25%	0.247	S	C	.	.	H	α-helix	trans	-84.6	-32.9	174.4	-73.2	-179.4	178.4	179.7	0	112.9	T133 M134 I135	T133-K137 HydrophobicContact CG2-CD 4.44Å; T133-K137 WeakPolarHBondContact O-CG 3.38Å; T133-K137 PolarHBondContact O-N 3.06Å; T133-K137 VanDerWaalsContact O-N 3.11Å; M134-K137 PolarHBondContact O-N 3.16Å; M134-K137 VanDerWaalsContact O-N 3.11Å; M134-K137 HydrophobicContact SD-CD 4.5Å; I135-K137 PolarHBondContact O-N 3.27Å
138	Y	84.1	Confident	82.5	Confident	4 Å²	4	53.6 Å²	53.6	2%	0.016	27%	0.267	C	S	.	.	H	α-helix	trans	-83.4	-31.3	-177.8	-95.1	-93.6	0	0	0	113.7	P14 D15 W18 V22 M134 I135 R196 L198	P14-Y138 WeakPolarHBondContact CD-O 3.42Å; P14-Y138 HydrophobicContact CG-CD1 3.76Å; P14-Y138 HydrophobicContact CG-CE1 4.14Å; D15-Y138 PolarHBondContact N-O 3.25Å; D15-Y138 VanDerWaalsContact N-O 3.1Å; W18-Y138 HydrophobicContact CB-CE1 4.34Å; V22-Y138 HydrophobicContact CB-CD2 4.47Å; V22-Y138 HydrophobicContact CG1-CD2 4.19Å; V22-Y138 HydrophobicContact CG1-CG 4.49Å; V22-Y138 HydrophobicContact CG2-CD2 4.09Å; V22-Y138 HydrophobicContact CG2-CE1 4.3Å; V22-Y138 HydrophobicContact CG2-CE2 3.82Å; V22-Y138 HydrophobicContact CG2-CG 4.45Å; M134-Y138 HydrophobicContact CE-CD2 3.94Å; M134-Y138 HydrophobicContact CE-CE2 3.47Å; M134-Y138 VanDerWaalsContact CE-CE2 3.47Å; M134-Y138 WeakPolarHBondContact O-CD2 3.41Å; M134-Y138 PolarHBondContact O-N 3.12Å; I135-Y138 PolarHBondContact O-N 3.49Å; Y138-R196 VanDerWaalsContact CE2-O 3.3Å; Y138-R196 WeakPolarHBondContact CE2-O 3.28Å; Y138-R196 PolarHBondContact OH-O 3.31Å; Y138-L198 HydrophobicContact CD1-CD1 3.81Å; Y138-L198 HydrophobicContact CD1-CD2 4.39Å; Y138-L198 HydrophobicContact CD1-CG 4.41Å; Y138-L198 HydrophobicContact CD2-CD1 3.48Å; Y138-L198 VanDerWaalsContact CD2-CD1 3.48Å; Y138-L198 HydrophobicContact CD2-CG 4.04Å; Y138-L198 HydrophobicContact CE1-CD1 3.86Å; Y138-L198 HydrophobicContact CE1-CD2 3.68Å; Y138-L198 HydrophobicContact CE1-CG 3.95Å; Y138-L198 HydrophobicContact CE2-CD1 3.49Å; Y138-L198 VanDerWaalsContact CE2-CD1 3.49Å; Y138-L198 HydrophobicContact CE2-CD2 4.11Å; Y138-L198 HydrophobicContact CE2-CG 3.48Å; Y138-L198 VanDerWaalsContact CE2-CG 3.48Å; Y138-L198 HydrophobicContact CG-CD1 3.65Å; Y138-L198 HydrophobicContact CG-CG 4.48Å; Y138-L198 VanDerWaalsContact CZ-CG 3.45Å; Y138-L198 WeakPolarHBondContact OH-CD2 3.4Å
139	F	79.4	Confident	82.4	Confident	1 Å²	1	56.2 Å²	56.2	0%	0.004	28%	0.281	C	S	.	.			trans	-123.9	133.1	-175.6	-63.8	-82.1	0	0	0	111.7	D15 G19 W20 V23 I135 K142 R143 A146	D15-F139 VanDerWaalsContact OD1-CA 3.24Å; D15-F139 WeakPolarHBondContact OD1-CA 3.37Å; G19-F139 VanDerWaalsContact C-CZ 3.46Å; G19-F139 WeakPolarHBondContact O-CE2 3.4Å; W20-F139 HydrophobicContact CD2-CZ 4.23Å; W20-F139 HydrophobicContact CE3-CZ 4.45Å; W20-F139 HydrophobicContact CZ2-CE1 4.44Å; V23-F139 HydrophobicContact CG2-CD2 4.4Å; V23-F139 HydrophobicContact CG2-CE2 3.56Å; V23-F139 HydrophobicContact CG2-CZ 4.06Å; I135-F139 HydrophobicContact CG2-CD2 4.32Å; I135-F139 PolarHBondContact O-N 3.27Å; F139-K142 HydrophobicContact CD1-CB 3.9Å; F139-K142 HydrophobicContact CE1-CB 4.47Å; F139-R143 HydrophobicContact CB-CB 4.17Å; F139-A146 HydrophobicContact CB-CB 4.41Å; F139-A146 HydrophobicContact CD2-CB 3.64Å; F139-A146 HydrophobicContact CE2-CB 3.97Å; F139-A146 HydrophobicContact CG-CB 3.95Å
140	Y	75.5	Confident	82.5	Confident	173 Å²	173	53.9 Å²	53.9	68%	0.678	27%	0.27	S	S	*	.	S	Bend	trans	-115.7	-58.2	170.5	-172.6	-100.6	0	0	0	110	P13 D15	P13-Y140 HydrophobicContact CG-CG 4.38Å; D15-Y140 PolarHBondContact OD1-N 3.36Å
141	K	74.4	Confident	82.4	Confident	180 Å²	180	55.7 Å²	55.7	78%	0.783	28%	0.279	S	S	*	.	T	Hydrogen-bonded Turn	trans	-71.4	-41.6	178.8	-67	-176.1	-179	-179.9	0	112.5	D15	D15-K141 PolarHBondContact OD1-N 3.42Å; D15-K141 VanDerWaalsContact OD1-N 3.15Å; D15-K141 WeakPolarHBondContact OD2-CB 3.39Å; D15-K141 PolarHBondContact OD2-N 3.46Å
142	K	78.2	Confident	82.3	Confident	93 Å²	93	56.6 Å²	56.6	40%	0.404	29%	0.286	S	S	.	.	T	Hydrogen-bonded Turn	trans	-96.6	14.8	-177.4	-61.6	178.9	-178.3	172.6	0	113.4	D15 W20 F139 I145 A146	D15-K142 PolarHBondContact OD1-N 2.83Å; W20-K142 HydrophobicContact CZ2-CD 4.37Å; F139-K142 HydrophobicContact CD1-CB 3.9Å; F139-K142 HydrophobicContact CE1-CB 4.47Å; K142-I145 PolarHBondContact O-N 3.13Å; K142-A146 PolarHBondContact O-N 3.14Å
143	R	75.1	Confident	82.5	Confident	110 Å²	110	54.2 Å²	54.2	42%	0.415	27%	0.274	S	S	.	.	H	α-helix	trans	-57.3	-42.8	-176.2	-171.4	177.7	177	-173.3	-0.2	114	F139 I145 A146 N147	F139-R143 HydrophobicContact CB-CB 4.17Å; R143-I145 VanDerWaalsContact C-N 3.34Å; R143-I145 PolarHBondContact O-N 2.97Å; R143-A146 PolarHBondContact O-N 3.31Å; R143-N147 WeakPolarHBondContact O-CB 3.38Å; R143-N147 PolarHBondContact O-N 3.44Å
144	P	74.9	Confident	82.8	Confident	98 Å²	98	52.6 Å²	52.6	64%	0.636	26%	0.264	S	S	*	.	H	α-helix	trans	-62.4	-40.6	177.6	-23.5	35.4	0	0	0	112.6	G148	P144-G148 PolarHBondContact O-N 3.23Å
145	I	83	Confident	83.2	Confident	99 Å²	99	52.4 Å²	52.4	51%	0.508	26%	0.263	S	S	.	.	H	α-helix	trans	-65.8	-46.6	178.1	-62.9	163.4	0	0	0	110.2	W20 K142 R143 G148 I149	W20-I145 HydrophobicContact CH2-CG2 4.38Å; K142-I145 PolarHBondContact O-N 3.13Å; R143-I145 VanDerWaalsContact C-N 3.34Å; R143-I145 PolarHBondContact O-N 2.97Å; I145-G148 PolarHBondContact O-N 2.72Å; I145-I149 HydrophobicContact CG2-CD1 3.92Å; I145-I149 WeakPolarHBondContact O-CG1 3.37Å; I145-I149 PolarHBondContact O-N 3.46Å
146	A	83.5	Confident	83.6	Confident	0 Å²	0	54.1 Å²	54.1	0%	0	27%	0.274	C	S	.	.	H	α-helix	trans	-62.2	-44.4	179.1	0	0	0	0	0	112.3	V23 I135 F139 K142 R143 A150	V23-A146 HydrophobicContact CG2-CB 3.78Å; I135-A146 HydrophobicContact CG2-CB 3.63Å; F139-A146 HydrophobicContact CB-CB 4.41Å; F139-A146 HydrophobicContact CD2-CB 3.64Å; F139-A146 HydrophobicContact CE2-CB 3.97Å; F139-A146 HydrophobicContact CG-CB 3.95Å; K142-A146 PolarHBondContact O-N 3.14Å; R143-A146 PolarHBondContact O-N 3.31Å; A146-A150 WeakPolarHBondContact O-CB 3.37Å; A146-A150 PolarHBondContact O-N 2.87Å
147	N	84.3	Confident	84.3	Confident	47 Å²	47	54.7 Å²	54.7	25%	0.251	27%	0.269	S	S	.	.	H	α-helix	trans	-63.4	-42.7	173.4	-83.2	-14.1	0	0	0	111.8	I135 R143 A150 M151	I135-N147 VanDerWaalsContact CG2-OD1 3.23Å; I135-N147 WeakPolarHBondContact CG2-OD1 3.24Å; R143-N147 WeakPolarHBondContact O-CB 3.38Å; R143-N147 PolarHBondContact O-N 3.44Å; N147-A150 PolarHBondContact O-N 2.99Å; N147-M151 VanDerWaalsContact O-CB 3.29Å; N147-M151 WeakPolarHBondContact O-CB 3.5Å; N147-M151 WeakPolarHBondContact O-CG 3.43Å; N147-M151 PolarHBondContact O-N 3.46Å
148	G	82.8	Confident	84.9	Confident	41 Å²	41	50 Å²	50	42%	0.423	25%	0.249	S	C	.	.	H	α-helix	trans	-59	-47.8	178.5	0	0	0	0	0	112.3	P144 I145 M151 A152	P144-G148 PolarHBondContact O-N 3.23Å; I145-G148 PolarHBondContact O-N 2.72Å; G148-M151 PolarHBondContact O-N 3.36Å; G148-A152 WeakPolarHBondContact O-CB 3.45Å; G148-A152 PolarHBondContact O-N 3.22Å
149	I	89.3	Confident	85.3	Confident	72 Å²	72	51.1 Å²	51.1	37%	0.369	26%	0.258	S	S	.	.	H	α-helix	trans	-61.3	-50.9	175.9	-67.1	164.9	0	0	0	110.1	W20 V23 F27 I145 M151 A152	W20-I149 HydrophobicContact CZ3-CD1 3.83Å; V23-I149 HydrophobicContact CG1-CB 3.99Å; V23-I149 HydrophobicContact CG1-CG2 3.63Å; F27-I149 HydrophobicContact CD2-CG2 4.36Å; F27-I149 WeakPolarHBondContact CD2-O 2.97Å; I145-I149 HydrophobicContact CG2-CD1 3.92Å; I145-I149 WeakPolarHBondContact O-CG1 3.37Å; I145-I149 PolarHBondContact O-N 3.46Å; I149-M151 VanDerWaalsContact C-N 3.32Å; I149-M151 PolarHBondContact O-N 2.96Å; I149-A152 WeakPolarHBondContact O-CB 3.42Å; I149-A152 PolarHBondContact O-N 2.99Å; I149-A152 VanDerWaalsContact O-N 3.11Å
150	A	89.4	Confident	86	Confident	0 Å²	0	54.6 Å²	54.6	0%	0	28%	0.282	C	S	.	.	H	α-helix	trans	-61.7	-38.8	-177.5	0	0	0	0	0	112.7	I30 I135 A146 N147 G153	I30-A150 HydrophobicContact CD1-CB 3.82Å; I135-A150 HydrophobicContact CD1-CB 3.5Å; A146-A150 WeakPolarHBondContact O-CB 3.37Å; A146-A150 PolarHBondContact O-N 2.87Å; N147-A150 PolarHBondContact O-N 2.99Å; A150-G153 PolarHBondContact O-N 3.26Å
151	M	86.5	Confident	86.9	Confident	37 Å²	37	46.9 Å²	46.9	18%	0.182	25%	0.252	C	S	.	.	H	α-helix	trans	-71.5	-26.8	176.5	-69.9	-67.4	-72.9	0	0	113.4	I30 Y34 N147 G148 I149 G153 S154 R294	I30-M151 HydrophobicContact CD1-SD 4.36Å; I30-M151 HydrophobicContact CG2-SD 3.9Å; Y34-M151 HydrophobicContact CE2-CE 4.36Å; Y34-M151 HydrophobicContact CE2-SD 4.48Å; N147-M151 VanDerWaalsContact O-CB 3.29Å; N147-M151 WeakPolarHBondContact O-CB 3.5Å; N147-M151 WeakPolarHBondContact O-CG 3.43Å; N147-M151 PolarHBondContact O-N 3.46Å; G148-M151 PolarHBondContact O-N 3.36Å; I149-M151 VanDerWaalsContact C-N 3.32Å; I149-M151 PolarHBondContact O-N 2.96Å; M151-G153 PolarHBondContact O-N 3.35Å; M151-S154 PolarHBondContact O-N 3.48Å; M151-R294 PolarHBondContact O-NH1 2.9Å
152	A	87.2	Confident	87.7	Confident	19 Å²	19	38.3 Å²	38.3	16%	0.157	22%	0.215	C	C	.	.	H	α-helix	trans	-67.7	-14.2	172	0	0	0	0	0	112.7	G148 I149 S154 P155 V156	G148-A152 WeakPolarHBondContact O-CB 3.45Å; G148-A152 PolarHBondContact O-N 3.22Å; I149-A152 WeakPolarHBondContact O-CB 3.42Å; I149-A152 PolarHBondContact O-N 2.99Å; I149-A152 VanDerWaalsContact O-N 3.11Å; A152-S154 VanDerWaalsContact C-N 3.28Å; A152-S154 PolarHBondContact O-N 3.04Å; A152-P155 WeakPolarHBondContact O-CD 3.49Å; A152-P155 VanDerWaalsContact O-CG 3.28Å; A152-P155 WeakPolarHBondContact O-CG 3.43Å; A152-V156 WeakPolarHBondContact O-CG2 3.3Å; A152-V156 PolarHBondContact O-N 3.13Å
153	G	89.4	Confident	88.3	Confident	0 Å²	0	35.8 Å²	35.8	0%	0	21%	0.208	C	C	.	.	H	α-helix	trans	-60.7	-35.7	171.3	0	0	0	0	0	113.2	F27 A150 M151 V156 F157	F27-G153 VanDerWaalsContact CE2-N 3.29Å; F27-G153 VanDerWaalsContact CZ-CA 3.44Å; A150-G153 PolarHBondContact O-N 3.26Å; M151-G153 PolarHBondContact O-N 3.35Å; G153-V156 PolarHBondContact O-N 2.86Å; G153-F157 WeakPolarHBondContact O-CB 3.33Å; G153-F157 VanDerWaalsContact O-CD2 3.26Å; G153-F157 WeakPolarHBondContact O-CD2 3.3Å; G153-F157 PolarHBondContact O-N 2.95Å
154	S	91.5	Very high	89.2	Confident	2 Å²	2	34.4 Å²	34.4	1%	0.014	21%	0.205	C	C	.	.	H	α-helix	trans	-56.4	-54.4	179.6	171.3	0	0	0	0	113.6	Y34 M151 A152 L158	Y34-S154 VanDerWaalsContact CB-OG 3.24Å; Y34-S154 WeakPolarHBondContact CB-OG 3.46Å; M151-S154 PolarHBondContact O-N 3.48Å; A152-S154 VanDerWaalsContact C-N 3.28Å; A152-S154 PolarHBondContact O-N 3.04Å; S154-L158 WeakPolarHBondContact O-CB 3.23Å; S154-L158 PolarHBondContact O-N 3.15Å
155	P	92.1	Very high	90.1	Very high	1 Å²	1	29.7 Å²	29.7	1%	0.006	18%	0.175	C	C	.	.	H	α-helix	trans	-66.8	-37	178.6	19.8	-30	0	0	0	113.2	A152 F157 L158 S159 A287 D290 M291	A152-P155 WeakPolarHBondContact O-CD 3.49Å; A152-P155 VanDerWaalsContact O-CG 3.28Å; A152-P155 WeakPolarHBondContact O-CG 3.43Å; P155-F157 PolarHBondContact O-N 2.95Å; P155-L158 PolarHBondContact O-N 2.95Å; P155-S159 PolarHBondContact O-N 2.94Å; P155-S159 PolarHBondContact O-OG 3.33Å; P155-A287 HydrophobicContact CB-CB 4.33Å; P155-A287 WeakPolarHBondContact CB-O 3.39Å; P155-A287 WeakPolarHBondContact O-CB 3.48Å; P155-D290 HydrophobicContact CB-CB 4.42Å; P155-M291 HydrophobicContact CB-CB 3.97Å; P155-M291 HydrophobicContact CG-CB 3.98Å; P155-M291 HydrophobicContact CG-CG 4.28Å
156	V	93.8	Very high	90.5	Very high	37 Å²	37	25 Å²	25	22%	0.224	15%	0.151	C	C	.	.	H	α-helix	trans	-62.3	-43.9	178.2	173.9	0	0	0	0	111.8	F27 A152 G153 S159 S160 M291	F27-V156 HydrophobicContact CZ-CB 4.04Å; F27-V156 HydrophobicContact CZ-CG1 4.17Å; F27-V156 HydrophobicContact CZ-CG2 4.1Å; A152-V156 WeakPolarHBondContact O-CG2 3.3Å; A152-V156 PolarHBondContact O-N 3.13Å; G153-V156 PolarHBondContact O-N 2.86Å; V156-S159 PolarHBondContact O-OG 3.4Å; V156-S160 PolarHBondContact O-N 3.42Å; V156-S160 PolarHBondContact O-OG 2.76Å; V156-M291 HydrophobicContact CG2-CE 3.46Å; V156-M291 VanDerWaalsContact CG2-CE 3.46Å; V156-M291 HydrophobicContact CG2-CG 4.3Å; V156-M291 HydrophobicContact CG2-SD 3.5Å; V156-M291 VanDerWaalsContact CG2-SD 3.5Å
157	F	94.9	Very high	91	Very high	35 Å²	35	30.8 Å²	30.8	15%	0.154	17%	0.173	C	C	.	.	H	α-helix	trans	-67.9	-39.9	176.6	-87.1	-108.1	0	0	0	111.1	F27 I28 F32 A35 G153 P155 S160 L161	F27-F157 AromaticContact CD1-CE2 3.87Å; F27-F157 HydrophobicContact CD1-CE2 3.87Å; F27-F157 HydrophobicContact CE1-CD2 4.15Å; F27-F157 AromaticContact CE1-CE2 3.67Å; F27-F157 HydrophobicContact CE1-CE2 3.67Å; I28-F157 HydrophobicContact CB-CZ 4.31Å; I28-F157 HydrophobicContact CG1-CZ 4.21Å; I28-F157 HydrophobicContact CG2-CZ 4.16Å; F32-F157 AromaticContact CD1-CD1 3.95Å; F32-F157 HydrophobicContact CD1-CD1 3.95Å; F32-F157 HydrophobicContact CD1-CE1 4.15Å; F32-F157 HydrophobicContact CD2-CD1 4.25Å; F32-F157 AromaticContact CD2-CE1 3.76Å; F32-F157 HydrophobicContact CD2-CE1 3.76Å; F32-F157 AromaticContact CE1-CD1 3.87Å; F32-F157 HydrophobicContact CE1-CD1 3.87Å; F32-F157 AromaticContact CE1-CE1 3.82Å; F32-F157 HydrophobicContact CE1-CE1 3.82Å; F32-F157 HydrophobicContact CE2-CD1 4.21Å; F32-F157 AromaticContact CE2-CE1 3.44Å; F32-F157 HydrophobicContact CE2-CE1 3.44Å; F32-F157 VanDerWaalsContact CE2-CE1 3.44Å; F32-F157 HydrophobicContact CE2-CZ 4.24Å; F32-F157 HydrophobicContact CG-CD1 4.14Å; F32-F157 HydrophobicContact CG-CE1 4.11Å; F32-F157 HydrophobicContact CZ-CD1 4.01Å; F32-F157 AromaticContact CZ-CE1 3.46Å; F32-F157 HydrophobicContact CZ-CE1 3.46Å; F32-F157 VanDerWaalsContact CZ-CE1 3.46Å; A35-F157 HydrophobicContact CB-CB 3.71Å; G153-F157 WeakPolarHBondContact O-CB 3.33Å; G153-F157 VanDerWaalsContact O-CD2 3.26Å; G153-F157 WeakPolarHBondContact O-CD2 3.3Å; G153-F157 PolarHBondContact O-N 2.95Å; P155-F157 PolarHBondContact O-N 2.95Å; F157-S160 PolarHBondContact O-N 3.31Å; F157-L161 HydrophobicContact CB-CD1 4.22Å; F157-L161 HydrophobicContact CD1-CD1 4.22Å; F157-L161 WeakPolarHBondContact O-CB 3.45Å; F157-L161 WeakPolarHBondContact O-CG 3.48Å; F157-L161 PolarHBondContact O-N 3.31Å
158	L	93.3	Very high	91.5	Very high	2 Å²	2	28.8 Å²	28.8	1%	0.01	16%	0.163	C	C	.	.	H	α-helix	trans	-64.8	-42.3	178.5	-178.4	57.7	0	0	0	112.2	A35 K38 A39 S154 P155 S160 A162 A287	A35-L158 HydrophobicContact CB-CB 3.87Å; K38-L158 HydrophobicContact CB-CD1 3.71Å; K38-L158 HydrophobicContact CB-CD2 4.16Å; K38-L158 HydrophobicContact CD-CD2 3.76Å; A39-L158 HydrophobicContact CB-CD1 4.07Å; S154-L158 WeakPolarHBondContact O-CB 3.23Å; S154-L158 PolarHBondContact O-N 3.15Å; P155-L158 PolarHBondContact O-N 2.95Å; L158-S160 VanDerWaalsContact C-N 3.28Å; L158-S160 PolarHBondContact O-N 3.47Å; L158-A162 WeakPolarHBondContact O-CB 3.36Å; L158-A162 PolarHBondContact O-N 2.87Å; L158-A162 VanDerWaalsContact O-N 3.1Å; L158-A287 HydrophobicContact CB-CB 3.87Å; L158-A287 HydrophobicContact CD2-CB 3.91Å; L158-A287 HydrophobicContact CG-CB 3.85Å
159	S	93.6	Very high	91.9	Very high	27 Å²	27	28.4 Å²	28.4	19%	0.189	15%	0.149	C	C	.	.	H	α-helix	trans	-66.2	-31.2	178.9	66.1	0	0	0	0	113.3	P155 V156 P163 S284	P155-S159 PolarHBondContact O-N 2.94Å; P155-S159 PolarHBondContact O-OG 3.33Å; V156-S159 PolarHBondContact O-OG 3.4Å; S159-P163 WeakPolarHBondContact O-CD 3.45Å; S159-P163 WeakPolarHBondContact O-CG 3.37Å; S159-S284 PolarHBondContact O-OG 3.41Å
160	S	93.8	Very high	92	Very high	73 Å²	73	28.5 Å²	28.5	51%	0.51	15%	0.151	S	C	.	.	H	α-helix	trans	-85.4	-41.4	178.1	-52.6	0	0	0	0	112	V156 F157 L158 P163 F164	V156-S160 PolarHBondContact O-N 3.42Å; V156-S160 PolarHBondContact O-OG 2.76Å; F157-S160 PolarHBondContact O-N 3.31Å; L158-S160 VanDerWaalsContact C-N 3.28Å; L158-S160 PolarHBondContact O-N 3.47Å; S160-P163 WeakPolarHBondContact O-CD 3.44Å; S160-P163 WeakPolarHBondContact O-CG 3.36Å; S160-F164 WeakPolarHBondContact O-CB 3.29Å; S160-F164 PolarHBondContact O-N 2.92Å
161	L	93.3	Very high	92.2	Very high	11 Å²	11	31.3 Å²	31.3	6%	0.058	17%	0.17	C	C	.	.	H	α-helix	trans	-72.2	-34.7	-175.9	-76.4	170.2	0	0	0	113.1	F32 A35 A39 F157 F164 N165 L181	F32-L161 HydrophobicContact CD1-CD1 4.21Å; F32-L161 HydrophobicContact CE1-CD1 4.22Å; A35-L161 HydrophobicContact CB-CD1 4.23Å; A39-L161 HydrophobicContact CB-CB 3.89Å; F157-L161 HydrophobicContact CB-CD1 4.22Å; F157-L161 HydrophobicContact CD1-CD1 4.22Å; F157-L161 WeakPolarHBondContact O-CB 3.45Å; F157-L161 WeakPolarHBondContact O-CG 3.48Å; F157-L161 PolarHBondContact O-N 3.31Å; L161-F164 HydrophobicContact CD2-CD1 4.45Å; L161-F164 PolarHBondContact O-N 3.2Å; L161-N165 WeakPolarHBondContact O-CB 3.4Å; L161-N165 PolarHBondContact O-N 2.94Å; L161-N165 PolarHBondContact O-OD1 3.38Å; L161-L181 HydrophobicContact CD2-CD2 4.42Å
162	A	91.6	Very high	92.5	Very high	0 Å²	0	35.3 Å²	35.3	0%	0	19%	0.187	C	C	.	.	H	α-helix	trans	-59.4	-53.3	-179.2	0	0	0	0	0	113.6	L158 N165 Q166 L283	L158-A162 WeakPolarHBondContact O-CB 3.36Å; L158-A162 PolarHBondContact O-N 2.87Å; L158-A162 VanDerWaalsContact O-N 3.1Å; A162-N165 PolarHBondContact O-N 2.93Å; A162-Q166 PolarHBondContact O-N 2.96Å; A162-L283 HydrophobicContact CB-CB 4.03Å; A162-L283 HydrophobicContact CB-CD1 4.41Å
163	P	92.1	Very high	92.8	Very high	40 Å²	40	35.9 Å²	35.9	26%	0.26	19%	0.194	S	C	.	.	H	α-helix	trans	-71.6	-34.7	178.2	27.7	-33.7	0	0	0	111.5	S159 S160 N165 Q166 Y167 S284	S159-P163 WeakPolarHBondContact O-CD 3.45Å; S159-P163 WeakPolarHBondContact O-CG 3.37Å; S160-P163 WeakPolarHBondContact O-CD 3.44Å; S160-P163 WeakPolarHBondContact O-CG 3.36Å; P163-N165 VanDerWaalsContact C-N 3.33Å; P163-N165 PolarHBondContact O-N 3.3Å; P163-Q166 PolarHBondContact O-N 3.46Å; P163-Y167 PolarHBondContact O-N 3.43Å; P163-S284 WeakPolarHBondContact CD-OG 3.32Å
164	F	94.2	Very high	92.9	Very high	81 Å²	81	36.5 Å²	36.5	36%	0.355	20%	0.197	S	C	.	.	H	α-helix	trans	-62.2	-40.4	175.2	-178.4	-108.9	0	0	0	112	S160 L161 Y167 L168 I184	S160-F164 WeakPolarHBondContact O-CB 3.29Å; S160-F164 PolarHBondContact O-N 2.92Å; L161-F164 HydrophobicContact CD2-CD1 4.45Å; L161-F164 PolarHBondContact O-N 3.2Å; F164-Y167 WeakPolarHBondContact O-CB 3.49Å; F164-Y167 PolarHBondContact O-N 3.01Å; F164-L168 HydrophobicContact CD1-CD1 3.91Å; F164-L168 HydrophobicContact CD1-CG 4.3Å; F164-L168 HydrophobicContact CE1-CD1 3.39Å; F164-L168 HydrophobicContact CE1-CD2 4.43Å; F164-L168 HydrophobicContact CE1-CG 3.92Å; F164-L168 HydrophobicContact CE2-CD2 4.42Å; F164-L168 HydrophobicContact CE2-CG 4.36Å; F164-L168 HydrophobicContact CZ-CD1 3.83Å; F164-L168 HydrophobicContact CZ-CD2 4.01Å; F164-L168 HydrophobicContact CZ-CG 3.95Å; F164-L168 WeakPolarHBondContact O-CG 3.26Å; F164-L168 PolarHBondContact O-N 2.93Å; F164-I184 HydrophobicContact CE1-CD1 3.55Å; F164-I184 HydrophobicContact CZ-CD1 4.07Å
165	N	93.6	Very high	93	Very high	0 Å²	0	41.1 Å²	41.1	0%	0	21%	0.214	C	C	.	.	H	α-helix	trans	-63.2	-42.1	174.7	-78.2	-5.7	0	0	0	111.9	A39 Y43 L161 A162 P163 Y167 L168 F169 L181	A39-N165 PolarHBondContact O-ND2 3.28Å; Y43-N165 HydrophobicContact CE2-CB 3.74Å; Y43-N165 WeakPolarHBondContact OH-CA 3.16Å; Y43-N165 WeakPolarHBondContact OH-CB 3.42Å; Y43-N165 PolarHBondContact OH-O 3.09Å; Y43-N165 VanDerWaalsContact OH-O 3.13Å; L161-N165 WeakPolarHBondContact O-CB 3.4Å; L161-N165 PolarHBondContact O-N 2.94Å; L161-N165 PolarHBondContact O-OD1 3.38Å; A162-N165 PolarHBondContact O-N 2.93Å; P163-N165 VanDerWaalsContact C-N 3.33Å; P163-N165 PolarHBondContact O-N 3.3Å; N165-Y167 VanDerWaalsContact C-N 3.31Å; N165-Y167 PolarHBondContact O-N 3.08Å; N165-L168 PolarHBondContact O-N 3.4Å; N165-F169 WeakPolarHBondContact O-CB 3.26Å; N165-F169 PolarHBondContact O-N 3.45Å; N165-L181 WeakPolarHBondContact OD1-CD2 3.31Å
166	Q	91.3	Very high	93.1	Very high	0 Å²	0	42.2 Å²	42.2	0%	0	23%	0.225	C	C	.	.	H	α-helix	trans	-64.6	-37.6	175.8	-172.2	62	60.8	0	0	111.6	V42 A162 P163 F169 N170 E276 Y277 A280	V42-Q166 HydrophobicContact CG1-CB 4Å; A162-Q166 PolarHBondContact O-N 2.96Å; P163-Q166 PolarHBondContact O-N 3.46Å; Q166-F169 PolarHBondContact O-N 3.45Å; Q166-N170 PolarHBondContact NE2-OD1 3.28Å; Q166-N170 VanDerWaalsContact O-CG 3.32Å; Q166-N170 PolarHBondContact O-N 2.87Å; Q166-E276 HydrophobicContact CG-CB 4.36Å; Q166-E276 PolarHBondContact NE2-OE2 3.39Å; Q166-Y277 HydrophobicContact CB-CD1 4.33Å; Q166-Y277 HydrophobicContact CB-CE1 4.34Å; Q166-Y277 HydrophobicContact CG-CD1 3.95Å; Q166-Y277 HydrophobicContact CG-CE1 4.1Å; Q166-Y277 HydrophobicContact CG-CG 4.19Å; Q166-A280 HydrophobicContact CB-CB 4Å; Q166-A280 HydrophobicContact CG-CB 4.41Å
167	Y	93.8	Very high	93.2	Very high	122 Å²	122	40.4 Å²	40.4	48%	0.478	21%	0.214	S	C	.	.	H	α-helix	trans	-64.2	-46	174	173.9	-96.3	0	0	0	112.8	P163 F164 N165 F169 N170 S171	P163-Y167 PolarHBondContact O-N 3.43Å; F164-Y167 WeakPolarHBondContact O-CB 3.49Å; F164-Y167 PolarHBondContact O-N 3.01Å; N165-Y167 VanDerWaalsContact C-N 3.31Å; N165-Y167 PolarHBondContact O-N 3.08Å; Y167-F169 VanDerWaalsContact C-N 3.3Å; Y167-F169 PolarHBondContact O-N 3.04Å; Y167-N170 PolarHBondContact O-N 2.9Å; Y167-S171 WeakPolarHBondContact O-CB 3.09Å; Y167-S171 PolarHBondContact O-N 3.13Å; Y167-S171 VanDerWaalsContact O-N 3.08Å; Y167-S171 PolarHBondContact O-OG 3.11Å
168	L	94.3	Very high	93.2	Very high	5 Å²	5	38.8 Å²	38.8	3%	0.026	21%	0.207	C	C	.	.	H	α-helix	trans	-60.6	-42.7	175.8	-73.9	-178.3	0	0	0	111.2	F164 N165 N170 S171 F172 S177 I180 L181	F164-L168 HydrophobicContact CD1-CD1 3.91Å; F164-L168 HydrophobicContact CD1-CG 4.3Å; F164-L168 HydrophobicContact CE1-CD1 3.39Å; F164-L168 HydrophobicContact CE1-CD2 4.43Å; F164-L168 HydrophobicContact CE1-CG 3.92Å; F164-L168 HydrophobicContact CE2-CD2 4.42Å; F164-L168 HydrophobicContact CE2-CG 4.36Å; F164-L168 HydrophobicContact CZ-CD1 3.83Å; F164-L168 HydrophobicContact CZ-CD2 4.01Å; F164-L168 HydrophobicContact CZ-CG 3.95Å; F164-L168 WeakPolarHBondContact O-CG 3.26Å; F164-L168 PolarHBondContact O-N 2.93Å; N165-L168 PolarHBondContact O-N 3.4Å; L168-N170 PolarHBondContact O-N 2.97Å; L168-S171 PolarHBondContact O-N 3.45Å; L168-F172 HydrophobicContact CD2-CD2 3.98Å; L168-F172 HydrophobicContact CD2-CE2 4.15Å; L168-F172 PolarHBondContact O-N 3.25Å; L168-S177 WeakPolarHBondContact CB-OG 3.42Å; L168-S177 PolarHBondContact O-OG 3.07Å; L168-S177 VanDerWaalsContact O-OG 3.14Å; L168-I180 HydrophobicContact CD1-CB 4.44Å; L168-I180 HydrophobicContact CD1-CG2 4.09Å; L168-I180 HydrophobicContact CD2-CD1 3.86Å; L168-I180 HydrophobicContact CD2-CG2 4.21Å; L168-L181 HydrophobicContact CD1-CD2 4.21Å; L168-L181 HydrophobicContact CD1-CG 4.13Å
169	F	90.8	Very high	93.4	Very high	32 Å²	32	42.6 Å²	42.6	14%	0.14	23%	0.227	C	C	.	.	H	α-helix	trans	-58.6	-49.1	177.6	-179	-105.3	0	0	0	111.5	Y43 D46 N165 Q166 Y167 S171 G173 W174 S177	Y43-F169 HydrophobicContact CD1-CB 4.13Å; Y43-F169 AromaticContact CD1-CD2 3.59Å; Y43-F169 HydrophobicContact CD1-CD2 3.59Å; Y43-F169 HydrophobicContact CD1-CE2 4.42Å; Y43-F169 HydrophobicContact CD1-CG 4.13Å; Y43-F169 HydrophobicContact CE1-CB 3.67Å; Y43-F169 AromaticContact CE1-CD2 3.85Å; Y43-F169 HydrophobicContact CE1-CD2 3.85Å; Y43-F169 HydrophobicContact CE1-CG 4.15Å; D46-F169 HydrophobicContact CB-CE1 4.06Å; D46-F169 HydrophobicContact CB-CE2 3.85Å; D46-F169 HydrophobicContact CB-CZ 3.36Å; N165-F169 WeakPolarHBondContact O-CB 3.26Å; N165-F169 PolarHBondContact O-N 3.45Å; Q166-F169 PolarHBondContact O-N 3.45Å; Y167-F169 VanDerWaalsContact C-N 3.3Å; Y167-F169 PolarHBondContact O-N 3.04Å; F169-S171 VanDerWaalsContact C-N 3.31Å; F169-S171 PolarHBondContact O-N 3.26Å; F169-G173 WeakPolarHBondContact O-CA 3.02Å; F169-G173 PolarHBondContact O-N 3.23Å; F169-W174 HydrophobicContact CD2-CB 4.02Å; F169-W174 HydrophobicContact CE2-CB 3.95Å; F169-S177 WeakPolarHBondContact CA-OG 3.24Å; F169-S177 PolarHBondContact N-OG 2.88Å; F169-S177 VanDerWaalsContact N-OG 3.16Å
170	N	91.1	Very high	93.5	Very high	75 Å²	75	44.2 Å²	44.2	40%	0.401	23%	0.233	S	C	.	.	H	α-helix	trans	-67.4	-31.3	-177.8	-71.1	-8.5	0	0	0	113	Q166 Y167 L168 Y277	Q166-N170 PolarHBondContact NE2-OD1 3.28Å; Q166-N170 VanDerWaalsContact O-CG 3.32Å; Q166-N170 PolarHBondContact O-N 2.87Å; Y167-N170 PolarHBondContact O-N 2.9Å; L168-N170 PolarHBondContact O-N 2.97Å; N170-Y277 WeakPolarHBondContact ND2-CE2 3.41Å
171	S	94.3	Very high	93.6	Very high	59 Å²	59	40.9 Å²	40.9	41%	0.413	21%	0.209	S	C	.	.	H	α-helix	trans	-88.7	-38.5	-175.7	-53.8	0	0	0	0	113.3	Y167 L168 F169	Y167-S171 WeakPolarHBondContact O-CB 3.09Å; Y167-S171 PolarHBondContact O-N 3.13Å; Y167-S171 VanDerWaalsContact O-N 3.08Å; Y167-S171 PolarHBondContact O-OG 3.11Å; L168-S171 PolarHBondContact O-N 3.45Å; F169-S171 VanDerWaalsContact C-N 3.31Å; F169-S171 PolarHBondContact O-N 3.26Å
172	F	93.3	Very high	93.6	Very high	121 Å²	121	40.3 Å²	40.3	53%	0.531	21%	0.206	S	C	.	.	H	α-helix	trans	-124.3	-2.1	-169.4	-58.2	-75.2	0	0	0	113.8	L168 I180	L168-F172 HydrophobicContact CD2-CD2 3.98Å; L168-F172 HydrophobicContact CD2-CE2 4.15Å; L168-F172 PolarHBondContact O-N 3.25Å; F172-I180 HydrophobicContact CD2-CD1 3.88Å; F172-I180 HydrophobicContact CE2-CD1 4.14Å; F172-I180 HydrophobicContact CG-CD1 4.2Å
173	G	92.8	Very high	93.8	Very high	30 Å²	30	42.2 Å²	42.2	31%	0.309	23%	0.226	S	C	.	.	H	α-helix	trans	69.2	176	-170.6	0	0	0	0	0	112.8	F169 R175 S177	F169-G173 WeakPolarHBondContact O-CA 3.02Å; F169-G173 PolarHBondContact O-N 3.23Å; G173-R175 PolarHBondContact O-N 3.34Å; G173-S177 VanDerWaalsContact O-CB 3.29Å; G173-S177 WeakPolarHBondContact O-CB 3.11Å; G173-S177 PolarHBondContact O-N 3.07Å; G173-S177 PolarHBondContact O-OG 2.97Å
174	W	91.6	Very high	93.9	Very high	13 Å²	13	42.2 Å²	42.2	5%	0.049	22%	0.223	C	C	.	.	H	α-helix	trans	-65.8	-36.1	-177.3	69	-87.8	0	0	0	113.5	Y43 I50 F51 C106 L112 F169 S177 F178	Y43-W174 HydrophobicContact CD1-CB 4.24Å; I50-W174 VanDerWaalsContact CD1-CD1 3.47Å; F51-W174 HydrophobicContact CE2-CH2 4.04Å; F51-W174 AromaticContact CE2-CZ2 3.83Å; F51-W174 HydrophobicContact CE2-CZ2 3.83Å; F51-W174 AromaticContact CZ-CH2 3.88Å; F51-W174 HydrophobicContact CZ-CH2 3.88Å; F51-W174 AromaticContact CZ-CZ2 3.73Å; F51-W174 HydrophobicContact CZ-CZ2 3.73Å; C106-W174 WeakPolarHBondContact O-CH2 3.27Å; L112-W174 HydrophobicContact CD2-CZ3 4.31Å; F169-W174 HydrophobicContact CD2-CB 4.02Å; F169-W174 HydrophobicContact CE2-CB 3.95Å; W174-S177 WeakPolarHBondContact O-CB 3.4Å; W174-S177 PolarHBondContact O-N 2.88Å; W174-F178 AromaticContact CE3-CD2 3.68Å; W174-F178 HydrophobicContact CE3-CD2 3.68Å; W174-F178 AromaticContact CE3-CE2 3.55Å; W174-F178 HydrophobicContact CE3-CE2 3.55Å; W174-F178 HydrophobicContact CE3-CZ 4.46Å; W174-F178 AromaticContact CZ3-CD2 3.98Å; W174-F178 HydrophobicContact CZ3-CD2 3.98Å; W174-F178 AromaticContact CZ3-CE2 3.93Å; W174-F178 HydrophobicContact CZ3-CE2 3.93Å; W174-F178 WeakPolarHBondContact O-CG 3.43Å; W174-F178 PolarHBondContact O-N 3.23Å
175	R	94.1	Very high	93.8	Very high	100 Å²	100	38.4 Å²	38.4	38%	0.377	21%	0.207	S	C	.	.	H	α-helix	trans	-65.7	-52	179.5	-66.8	-170	166.1	96.3	-5.1	111.7	S104 C106 N107 G173 S177 F178 L179	S104-R175 VanDerWaalsContact CB-O 3.23Å; S104-R175 WeakPolarHBondContact CB-O 3.45Å; S104-R175 WeakPolarHBondContact O-CD 3.2Å; S104-R175 WeakPolarHBondContact O-CG 3.43Å; C106-R175 PolarHBondContact O-NH2 3.37Å; N107-R175 PolarHBondContact OD1-NH2 3.26Å; G173-R175 PolarHBondContact O-N 3.34Å; R175-S177 VanDerWaalsContact C-N 3.26Å; R175-S177 PolarHBondContact O-N 3.05Å; R175-F178 PolarHBondContact O-N 2.95Å; R175-L179 PolarHBondContact O-N 3.29Å
176	G	94.4	Very high	93.8	Very high	23 Å²	23	42.1 Å²	42.1	24%	0.237	23%	0.226	C	C	.	.	H	α-helix	trans	-61.4	-37.2	175.8	0	0	0	0	0	112.1	L179 I180	G176-L179 PolarHBondContact O-N 2.99Å; G176-I180 WeakPolarHBondContact O-CG1 3.27Å; G176-I180 PolarHBondContact O-N 3.15Å; G176-I180 VanDerWaalsContact O-N 3.08Å
177	S	95.4	Very high	93.9	Very high	0 Å²	0	46.2 Å²	46.2	0%	0	25%	0.248	C	C	.	.	H	α-helix	trans	-60.6	-47.2	175.4	-60.1	0	0	0	0	112.7	Y43 L168 F169 G173 W174 R175 L179 I180 L181	Y43-S177 WeakPolarHBondContact OH-CB 3.2Å; L168-S177 WeakPolarHBondContact CB-OG 3.42Å; L168-S177 PolarHBondContact O-OG 3.07Å; L168-S177 VanDerWaalsContact O-OG 3.14Å; F169-S177 WeakPolarHBondContact CA-OG 3.24Å; F169-S177 PolarHBondContact N-OG 2.88Å; F169-S177 VanDerWaalsContact N-OG 3.16Å; G173-S177 VanDerWaalsContact O-CB 3.29Å; G173-S177 WeakPolarHBondContact O-CB 3.11Å; G173-S177 PolarHBondContact O-N 3.07Å; G173-S177 PolarHBondContact O-OG 2.97Å; W174-S177 WeakPolarHBondContact O-CB 3.4Å; W174-S177 PolarHBondContact O-N 2.88Å; R175-S177 VanDerWaalsContact C-N 3.26Å; R175-S177 PolarHBondContact O-N 3.05Å; S177-L179 VanDerWaalsContact C-N 3.32Å; S177-L179 PolarHBondContact O-N 3.31Å; S177-I180 PolarHBondContact O-N 2.95Å; S177-L181 WeakPolarHBondContact O-CB 3.31Å; S177-L181 VanDerWaalsContact O-CG 3.26Å; S177-L181 WeakPolarHBondContact O-CG 3.13Å; S177-L181 PolarHBondContact O-N 2.92Å
178	F	95.4	Very high	93.8	Very high	0 Å²	0	40.4 Å²	40.4	0%	0	23%	0.225	C	C	.	.	H	α-helix	trans	-65.3	-34.8	178.7	-70.3	-12.9	0	0	0	112.8	I40 Y43 I47 A103 L112 I116 W174 R175 L181 G182	I40-F178 HydrophobicContact CD1-CE1 3.89Å; I40-F178 HydrophobicContact CD1-CZ 4.04Å; I40-F178 HydrophobicContact CG1-CE1 3.94Å; I40-F178 HydrophobicContact CG1-CZ 4.26Å; Y43-F178 HydrophobicContact CD1-CE1 4.49Å; Y43-F178 AromaticContact CD2-CE1 3.95Å; Y43-F178 HydrophobicContact CD2-CE1 3.95Å; Y43-F178 HydrophobicContact CE2-CE1 4.12Å; Y43-F178 HydrophobicContact CG-CE1 4.16Å; Y43-F178 HydrophobicContact CG-CZ 4.5Å; I47-F178 HydrophobicContact CD1-CE2 4.28Å; I47-F178 HydrophobicContact CD1-CZ 3.93Å; A103-F178 HydrophobicContact CB-CD2 4.12Å; L112-F178 HydrophobicContact CD2-CE2 4.48Å; I116-F178 HydrophobicContact CD1-CD2 4.29Å; I116-F178 HydrophobicContact CD1-CE2 3.7Å; I116-F178 HydrophobicContact CD1-CZ 3.95Å; W174-F178 AromaticContact CE3-CD2 3.68Å; W174-F178 HydrophobicContact CE3-CD2 3.68Å; W174-F178 AromaticContact CE3-CE2 3.55Å; W174-F178 HydrophobicContact CE3-CE2 3.55Å; W174-F178 HydrophobicContact CE3-CZ 4.46Å; W174-F178 AromaticContact CZ3-CD2 3.98Å; W174-F178 HydrophobicContact CZ3-CD2 3.98Å; W174-F178 AromaticContact CZ3-CE2 3.93Å; W174-F178 HydrophobicContact CZ3-CE2 3.93Å; W174-F178 WeakPolarHBondContact O-CG 3.43Å; W174-F178 PolarHBondContact O-N 3.23Å; R175-F178 PolarHBondContact O-N 2.95Å; F178-L181 HydrophobicContact CD1-CD1 4.34Å; F178-G182 PolarHBondContact O-N 3.24Å
179	L	96.2	Very high	93.7	Very high	83 Å²	83	41.1 Å²	41.1	44%	0.435	23%	0.23	S	C	.	.	H	α-helix	trans	-62.2	-47.5	173.8	-171.5	70.6	0	0	0	111.5	I101 R175 G176 S177 G182 G183	I101-L179 HydrophobicContact CB-CD1 4.4Å; I101-L179 HydrophobicContact CG1-CD1 4.16Å; I101-L179 HydrophobicContact CG2-CD1 3.82Å; R175-L179 PolarHBondContact O-N 3.29Å; G176-L179 PolarHBondContact O-N 2.99Å; S177-L179 VanDerWaalsContact C-N 3.32Å; S177-L179 PolarHBondContact O-N 3.31Å; L179-G182 PolarHBondContact O-N 3.02Å; L179-G183 PolarHBondContact O-N 3.42Å
180	I	96.7	Very high	93.9	Very high	61 Å²	61	43.9 Å²	43.9	31%	0.313	25%	0.25	S	C	.	.	H	α-helix	trans	-65.3	-45.1	178.3	-66	166.6	0	0	0	110.8	L168 F172 G176 S177 G182 G183 I184	L168-I180 HydrophobicContact CD1-CB 4.44Å; L168-I180 HydrophobicContact CD1-CG2 4.09Å; L168-I180 HydrophobicContact CD2-CD1 3.86Å; L168-I180 HydrophobicContact CD2-CG2 4.21Å; F172-I180 HydrophobicContact CD2-CD1 3.88Å; F172-I180 HydrophobicContact CE2-CD1 4.14Å; F172-I180 HydrophobicContact CG-CD1 4.2Å; G176-I180 WeakPolarHBondContact O-CG1 3.27Å; G176-I180 PolarHBondContact O-N 3.15Å; G176-I180 VanDerWaalsContact O-N 3.08Å; S177-I180 PolarHBondContact O-N 2.95Å; I180-G182 VanDerWaalsContact C-N 3.26Å; I180-G182 PolarHBondContact O-N 2.83Å; I180-G183 PolarHBondContact O-N 3.04Å; I180-G183 VanDerWaalsContact O-N 3.11Å; I180-I184 HydrophobicContact CG2-CD1 4.08Å; I180-I184 WeakPolarHBondContact O-CG1 3.26Å; I180-I184 PolarHBondContact O-N 3.44Å
181	L	94.8	Very high	93.9	Very high	2 Å²	2	40.4 Å²	40.4	1%	0.01	23%	0.232	C	C	.	.	H	α-helix	trans	-63.2	-32.6	177.5	-72.7	171.2	0	0	0	112.2	F36 Y43 L100 L161 N165 L168 S177 F178 I184 L185	F36-L181 HydrophobicContact CE2-CB 4.27Å; F36-L181 HydrophobicContact CE2-CD1 4.23Å; F36-L181 HydrophobicContact CE2-CD2 4.41Å; F36-L181 HydrophobicContact CZ-CD1 4.49Å; Y43-L181 HydrophobicContact CE2-CD1 4.18Å; L100-L181 HydrophobicContact CD2-CB 3.54Å; L161-L181 HydrophobicContact CD2-CD2 4.42Å; N165-L181 WeakPolarHBondContact OD1-CD2 3.31Å; L168-L181 HydrophobicContact CD1-CD2 4.21Å; L168-L181 HydrophobicContact CD1-CG 4.13Å; S177-L181 WeakPolarHBondContact O-CB 3.31Å; S177-L181 VanDerWaalsContact O-CG 3.26Å; S177-L181 WeakPolarHBondContact O-CG 3.13Å; S177-L181 PolarHBondContact O-N 2.92Å; F178-L181 HydrophobicContact CD1-CD1 4.34Å; L181-I184 HydrophobicContact CD2-CD1 4.3Å; L181-I184 PolarHBondContact O-N 3.25Å; L181-L185 PolarHBondContact O-N 3.28Å
182	G	94.6	Very high	93.7	Very high	0 Å²	0	37.6 Å²	37.6	0%	0	21%	0.212	C	C	.	.	H	α-helix	trans	-60.8	-45.9	171.6	0	0	0	0	0	111.7	S97 F178 L179 I180 I184 L185 L186	S97-G182 WeakPolarHBondContact CB-O 3.29Å; S97-G182 PolarHBondContact OG-O 3.49Å; S97-G182 VanDerWaalsContact OG-O 3.05Å; F178-G182 PolarHBondContact O-N 3.24Å; L179-G182 PolarHBondContact O-N 3.02Å; I180-G182 VanDerWaalsContact C-N 3.26Å; I180-G182 PolarHBondContact O-N 2.83Å; G182-I184 VanDerWaalsContact C-N 3.34Å; G182-I184 PolarHBondContact O-N 3.22Å; G182-L185 PolarHBondContact O-N 3.49Å; G182-L186 PolarHBondContact O-N 2.93Å; G182-L186 VanDerWaalsContact O-N 3.07Å
183	G	94.6	Very high	93.7	Very high	40 Å²	40	33.9 Å²	33.9	41%	0.412	20%	0.204	S	C	.	.	H	α-helix	trans	-61.5	-39	173.4	0	0	0	0	0	113.2	L179 I180 L186	L179-G183 PolarHBondContact O-N 3.42Å; I180-G183 PolarHBondContact O-N 3.04Å; I180-G183 VanDerWaalsContact O-N 3.11Å; G183-L186 VanDerWaalsContact O-CB 3.28Å; G183-L186 WeakPolarHBondContact O-CB 3.36Å; G183-L186 PolarHBondContact O-N 3.32Å
184	I	94.1	Very high	93.6	Very high	39 Å²	39	34.7 Å²	34.7	20%	0.2	20%	0.2	C	C	.	.	H	α-helix	trans	-65.6	-41.9	175.6	-68.9	169.9	0	0	0	111.1	F32 F164 I180 L181 G182 L186 N187	F32-I184 HydrophobicContact CE1-CG2 3.58Å; F32-I184 HydrophobicContact CZ-CG2 3.39Å; F164-I184 HydrophobicContact CE1-CD1 3.55Å; F164-I184 HydrophobicContact CZ-CD1 4.07Å; I180-I184 HydrophobicContact CG2-CD1 4.08Å; I180-I184 WeakPolarHBondContact O-CG1 3.26Å; I180-I184 PolarHBondContact O-N 3.44Å; L181-I184 HydrophobicContact CD2-CD1 4.3Å; L181-I184 PolarHBondContact O-N 3.25Å; G182-I184 VanDerWaalsContact C-N 3.34Å; G182-I184 PolarHBondContact O-N 3.22Å; I184-L186 PolarHBondContact O-N 3.24Å; I184-N187 VanDerWaalsContact O-CB 3.23Å; I184-N187 WeakPolarHBondContact O-CB 3.36Å; I184-N187 PolarHBondContact O-N 3.27Å; I184-N187 PolarHBondContact O-ND2 3.35Å
185	L	92.7	Very high	93.5	Very high	1 Å²	1	34.1 Å²	34.1	1%	0.005	20%	0.198	C	C	.	.	H	α-helix	trans	-65.5	-24.7	175.8	-81.6	170.4	0	0	0	112.9	F32 F36 L100 L124 L181 G182 N187 C188	F32-L185 HydrophobicContact CB-CD2 3.97Å; F32-L185 HydrophobicContact CD1-CD2 3.86Å; F32-L185 HydrophobicContact CG-CD2 3.96Å; F36-L185 HydrophobicContact CD2-CD1 4.29Å; F36-L185 HydrophobicContact CD2-CD2 4.49Å; F36-L185 HydrophobicContact CE1-CD1 4.45Å; F36-L185 HydrophobicContact CE2-CD1 4.08Å; F36-L185 HydrophobicContact CZ-CD1 4.22Å; L100-L185 HydrophobicContact CD1-CD1 3.48Å; L100-L185 VanDerWaalsContact CD1-CD1 3.48Å; L100-L185 HydrophobicContact CD2-CD1 3.42Å; L100-L185 VanDerWaalsContact CD2-CD1 3.42Å; L100-L185 HydrophobicContact CG-CD1 4.01Å; L124-L185 HydrophobicContact CD2-CD2 4.05Å; L181-L185 PolarHBondContact O-N 3.28Å; G182-L185 PolarHBondContact O-N 3.49Å; L185-N187 PolarHBondContact O-N 3.44Å; L185-C188 WeakPolarHBondContact O-CB 3.5Å; L185-C188 PolarHBondContact O-N 2.97Å; L185-C188 PolarHBondContact O-SG 3.03Å; L185-C188 VanDerWaalsContact O-SG 3.37Å
186	L	94.3	Very high	93.1	Very high	78 Å²	78	37.2 Å²	37.2	41%	0.408	21%	0.21	S	C	.	.	H	α-helix	trans	-62.4	-22.1	172.6	-158.1	71.2	0	0	0	112.1	V94 G182 G183 I184 C188 C189	V94-L186 HydrophobicContact CG2-CD1 4.26Å; G182-L186 PolarHBondContact O-N 2.93Å; G182-L186 VanDerWaalsContact O-N 3.07Å; G183-L186 VanDerWaalsContact O-CB 3.28Å; G183-L186 WeakPolarHBondContact O-CB 3.36Å; G183-L186 PolarHBondContact O-N 3.32Å; I184-L186 PolarHBondContact O-N 3.24Å; L186-C188 PolarHBondContact O-N 3.34Å; L186-C189 WeakPolarHBondContact O-CB 3.04Å; L186-C189 PolarHBondContact O-N 2.91Å; L186-C189 PolarHBondContact O-SG 3.45Å
187	N	93.3	Very high	92.5	Very high	86 Å²	86	40.3 Å²	40.3	46%	0.46	23%	0.226	S	C	.	.	H	α-helix	trans	-63.8	-17.3	171	-68.2	-42.6	0	0	0	113.1	I184 L185 C189 V190 A191	I184-N187 VanDerWaalsContact O-CB 3.23Å; I184-N187 WeakPolarHBondContact O-CB 3.36Å; I184-N187 PolarHBondContact O-N 3.27Å; I184-N187 PolarHBondContact O-ND2 3.35Å; L185-N187 PolarHBondContact O-N 3.44Å; N187-C189 PolarHBondContact O-N 3.46Å; N187-V190 WeakPolarHBondContact O-CB 3.41Å; N187-V190 PolarHBondContact O-N 3.07Å; N187-A191 PolarHBondContact O-N 3.35Å
188	C	91.2	Very high	91.3	Very high	0 Å²	0	43.2 Å²	43.2	0%	0	24%	0.241	C	C	.	.	H	α-helix	trans	-59.2	-29.5	167.5	-68.2	0	0	0	0	111.9	F32 L185 L186 A191 G192	F32-C188 WeakPolarHBondContact CD2-SG 3.49Å; L185-C188 WeakPolarHBondContact O-CB 3.5Å; L185-C188 PolarHBondContact O-N 2.97Å; L185-C188 PolarHBondContact O-SG 3.03Å; L185-C188 VanDerWaalsContact O-SG 3.37Å; L186-C188 PolarHBondContact O-N 3.34Å; C188-A191 PolarHBondContact O-N 2.86Å; C188-G192 PolarHBondContact O-N 2.88Å
189	C	92.9	Very high	89.8	Confident	20 Å²	20	45 Å²	45	14%	0.135	26%	0.259	C	S	.	.	H	α-helix	trans	-66.3	-38.4	173.2	-58.5	0	0	0	0	111.7	I90 G93 V94 L186 N187 G192 A193	I90-C189 HydrophobicContact CG2-CB 4.42Å; I90-C189 PolarHBondContact O-SG 3.45Å; G93-C189 VanDerWaalsContact C-SG 3.6Å; V94-C189 PolarHBondContact N-SG 3.27Å; V94-C189 VanDerWaalsContact N-SG 3.45Å; L186-C189 WeakPolarHBondContact O-CB 3.04Å; L186-C189 PolarHBondContact O-N 2.91Å; L186-C189 PolarHBondContact O-SG 3.45Å; N187-C189 PolarHBondContact O-N 3.46Å; C189-G192 CarbonylContact O-C 3.52Å; C189-G192 PolarHBondContact O-N 2.86Å; C189-A193 PolarHBondContact O-N 3.23Å
190	V	93.4	Very high	87.9	Confident	91 Å²	91	44.9 Å²	44.9	55%	0.552	26%	0.264	S	S	*	.	H	α-helix	trans	-66.1	-43.8	175.4	-177.2	0	0	0	0	109.9	N187 G192 A193 L194	N187-V190 WeakPolarHBondContact O-CB 3.41Å; N187-V190 PolarHBondContact O-N 3.07Å; V190-G192 VanDerWaalsContact C-N 3.27Å; V190-G192 PolarHBondContact O-N 2.83Å; V190-A193 WeakPolarHBondContact O-CB 3.44Å; V190-A193 PolarHBondContact O-N 2.87Å; V190-A193 VanDerWaalsContact O-N 3.07Å; V190-L194 PolarHBondContact O-N 3.41Å
191	A	91.4	Very high	85.8	Confident	2 Å²	2	46.1 Å²	46.1	2%	0.017	28%	0.276	C	S	.	.	H	α-helix	trans	-58.4	-39	171.9	0	0	0	0	0	112.1	I28 N187 C188 L194	I28-A191 HydrophobicContact CB-CB 4.06Å; I28-A191 HydrophobicContact CG2-CB 4.06Å; N187-A191 PolarHBondContact O-N 3.35Å; C188-A191 PolarHBondContact O-N 2.86Å; A191-L194 WeakPolarHBondContact O-CB 3.41Å; A191-L194 PolarHBondContact O-N 3.02Å
192	G	90.6	Very high	83.9	Confident	0 Å²	0	50.2 Å²	50.2	0%	0	30%	0.297	C	S	.	.	H	α-helix	trans	-65.8	-32.9	172.7	0	0	0	0	0	114.4	C188 C189 V190 L194 M195	C188-G192 PolarHBondContact O-N 2.88Å; C189-G192 CarbonylContact O-C 3.52Å; C189-G192 PolarHBondContact O-N 2.86Å; V190-G192 VanDerWaalsContact C-N 3.27Å; V190-G192 PolarHBondContact O-N 2.83Å; G192-L194 PolarHBondContact O-N 2.93Å; G192-M195 VanDerWaalsContact O-CB 3.31Å; G192-M195 WeakPolarHBondContact O-CB 3.48Å; G192-M195 PolarHBondContact O-N 2.98Å; G192-M195 VanDerWaalsContact O-N 3.16Å
193	A	92.4	Very high	81.8	Confident	43 Å²	43	52.7 Å²	52.7	36%	0.355	32%	0.323	S	S	.	.	H	α-helix	trans	-66.5	-26.8	177.6	0	0	0	0	0	112.9	C189 V190 M195	C189-A193 PolarHBondContact O-N 3.23Å; V190-A193 WeakPolarHBondContact O-CB 3.44Å; V190-A193 PolarHBondContact O-N 2.87Å; V190-A193 VanDerWaalsContact O-N 3.07Å; A193-M195 PolarHBondContact O-N 3.36Å
194	L	92.6	Very high	79.4	Confident	46 Å²	46	57 Å²	57	24%	0.241	33%	0.331	C	S	.	.	T	Hydrogen-bonded Turn	trans	-69	-18.1	175.4	-63	172.8	0	0	0	113.1	W18 V190 A191 G192 R196	W18-L194 HydrophobicContact CZ2-CD2 4.36Å; W18-L194 PolarHBondContact NE1-O 3.06Å; V190-L194 PolarHBondContact O-N 3.41Å; A191-L194 WeakPolarHBondContact O-CB 3.41Å; A191-L194 PolarHBondContact O-N 3.02Å; G192-L194 PolarHBondContact O-N 2.93Å; L194-R196 PolarHBondContact O-N 3.23Å
195	M	88	Confident	77.3	Confident	1 Å²	1	58.6 Å²	58.6	1%	0.005	34%	0.338	C	S	.	.			trans	-76.5	82	-177.8	-58.3	-61.2	168.9	0	0	111.6	V22 S26 R86 M89 M134 G192 A193	V22-M195 HydrophobicContact CB-SD 4.28Å; V22-M195 HydrophobicContact CG1-CE 4.38Å; V22-M195 HydrophobicContact CG1-SD 3.68Å; V22-M195 HydrophobicContact CG2-SD 4.19Å; S26-M195 WeakPolarHBondContact OG-CE 3.3Å; R86-M195 HydrophobicContact CB-CB 4.48Å; M89-M195 HydrophobicContact CE-CE 3.7Å; M89-M195 HydrophobicContact CE-CG 3.8Å; M89-M195 HydrophobicContact SD-CB 4.46Å; M89-M195 HydrophobicContact SD-CE 4.15Å; M89-M195 HydrophobicContact SD-CG 3.5Å; M89-M195 WeakPolarHBondContact SD-CG 3.42Å; M89-M195 HydrophobicContact SD-SD 4.37Å; M134-M195 HydrophobicContact CB-SD 3.75Å; M134-M195 HydrophobicContact CE-CB 4.13Å; M134-M195 HydrophobicContact CG-CB 4.23Å; M134-M195 HydrophobicContact CG-CG 4.31Å; M134-M195 HydrophobicContact CG-SD 3.83Å; G192-M195 VanDerWaalsContact O-CB 3.31Å; G192-M195 WeakPolarHBondContact O-CB 3.48Å; G192-M195 PolarHBondContact O-N 2.98Å; G192-M195 VanDerWaalsContact O-N 3.16Å; A193-M195 PolarHBondContact O-N 3.36Å
196	R	86.9	Confident	75.1	Confident	165 Å²	165	65.4 Å²	65.4	62%	0.623	37%	0.368	S	S	*	.			trans	-78.2	125.9	177.8	-174.1	176.2	-176	178.5	1.4	110.5	M134 Y138 L194	M134-R196 WeakPolarHBondContact CE-O 3.43Å; Y138-R196 VanDerWaalsContact CE2-O 3.3Å; Y138-R196 WeakPolarHBondContact CE2-O 3.28Å; Y138-R196 PolarHBondContact OH-O 3.31Å; L194-R196 PolarHBondContact O-N 3.23Å
197	P	80.9	Confident	72.7	Confident	89 Å²	89	68.4 Å²	68.4	58%	0.578	38%	0.378	S	S	*	.			trans	-68.4	135.1	175.4	27	-32.2	0	0	0	110.6
198	L	70	Confident	70.4	Confident	60 Å²	60	69 Å²	69	31%	0.314	38%	0.381	S	S	.	.	S	Bend	trans	-87.4	4.6	-177.4	-75.6	172.5	0	0	0	114.6	P14 Y138	P14-L198 HydrophobicContact CG-CD1 4.13Å; P14-L198 HydrophobicContact CG-CD2 4.17Å; Y138-L198 HydrophobicContact CD1-CD1 3.81Å; Y138-L198 HydrophobicContact CD1-CD2 4.39Å; Y138-L198 HydrophobicContact CD1-CG 4.41Å; Y138-L198 HydrophobicContact CD2-CD1 3.48Å; Y138-L198 VanDerWaalsContact CD2-CD1 3.48Å; Y138-L198 HydrophobicContact CD2-CG 4.04Å; Y138-L198 HydrophobicContact CE1-CD1 3.86Å; Y138-L198 HydrophobicContact CE1-CD2 3.68Å; Y138-L198 HydrophobicContact CE1-CG 3.95Å; Y138-L198 HydrophobicContact CE2-CD1 3.49Å; Y138-L198 VanDerWaalsContact CE2-CD1 3.49Å; Y138-L198 HydrophobicContact CE2-CD2 4.11Å; Y138-L198 HydrophobicContact CE2-CG 3.48Å; Y138-L198 VanDerWaalsContact CE2-CG 3.48Å; Y138-L198 HydrophobicContact CG-CD1 3.65Å; Y138-L198 HydrophobicContact CG-CG 4.48Å; Y138-L198 VanDerWaalsContact CZ-CG 3.45Å; Y138-L198 WeakPolarHBondContact OH-CD2 3.4Å
199	G	64.4	Low	68.2	Low	37 Å²	37	74.8 Å²	74.8	38%	0.381	41%	0.408	S	S	.	.	S	Bend	trans	-142.9	174.7	-179.5	0	0	0	0	0	113
200	P	55.6	Low	65.8	Low	81 Å²	81	80.1 Å²	80.1	53%	0.526	43%	0.431	S	S	.	.	S	Bend	trans	-53	149.9	173.2	-20.1	30.5	0	0	0	110.6	L202 I205	P200-L202 PolarHBondContact O-N 3.01Å; P200-I205 HydrophobicContact CB-CG1 4.5Å
201	P	54.3	Low	63.4	Low	88 Å²	88	81.3 Å²	81.3	57%	0.571	43%	0.434	S	S	*	.			trans	-51.8	133.1	174.9	-19.6	29.1	0	0	0	109.5	G203 K204	P201-G203 PolarHBondContact O-N 3.02Å; P201-K204 PolarHBondContact O-N 3.29Å
202	L	54.8	Low	61.2	Low	87 Å²	87	86.1 Å²	86.1	46%	0.455	46%	0.462	S	S	.	.	H	α-helix	trans	-50.4	-24.9	-179.8	-84.3	130.4	0	0	0	113.3	P200 K206	P200-L202 PolarHBondContact O-N 3.01Å; L202-K206 PolarHBondContact O-N 2.89Å
203	G	48.7	Very low	59.1	Low	53 Å²	53	90.4 Å²	90.4	55%	0.546	49%	0.488	S	S	.	.	H	α-helix	trans	-72.9	-16.5	174.5	0	0	0	0	0	116.4	P201	P201-G203 PolarHBondContact O-N 3.02Å
204	K	44.7	Very low	56.5	Low	131 Å²	131	92.5 Å²	92.5	57%	0.57	51%	0.506	S	S	*	.	H	α-helix	trans	-87.4	-36.2	173.4	-78.7	-171.6	172.1	-174.9	0	112.3	P201 K206 K207 D208	P201-K204 PolarHBondContact O-N 3.29Å; K204-K206 VanDerWaalsContact C-N 3.31Å; K204-K206 PolarHBondContact O-N 2.91Å; K204-K207 PolarHBondContact O-N 3Å; K204-D208 PolarHBondContact O-N 3.34Å
205	I	49.9	Very low	53.9	Low	71 Å²	71	99.2 Å²	99.2	36%	0.364	53%	0.533	S	S	.	.	H	α-helix	trans	-62.7	-39.8	176.1	-58.7	173.2	0	0	0	110.4	P200 K207 D208 E209	P200-I205 HydrophobicContact CB-CG1 4.5Å; I205-K207 VanDerWaalsContact C-N 3.32Å; I205-K207 PolarHBondContact O-N 3.3Å; I205-D208 PolarHBondContact O-N 3.46Å; I205-E209 HydrophobicContact CG2-CG 4.17Å; I205-E209 VanDerWaalsContact O-CB 3.25Å; I205-E209 WeakPolarHBondContact O-CB 3.36Å; I205-E209 WeakPolarHBondContact O-CG 3.25Å; I205-E209 PolarHBondContact O-N 3.35Å
206	K	47.9	Very low	51.4	Low	144 Å²	144	105.1 Å²	105.1	63%	0.626	57%	0.569	S	S	*	*	H	α-helix	trans	-61.6	-36	172.1	-80.4	-173.4	174.8	-177	0	113.4	L202 K204 E210	L202-K206 PolarHBondContact O-N 2.89Å; K204-K206 VanDerWaalsContact C-N 3.31Å; K204-K206 PolarHBondContact O-N 2.91Å; K206-E210 WeakPolarHBondContact O-CB 3.35Å; K206-E210 WeakPolarHBondContact O-CG 3.36Å; K206-E210 PolarHBondContact O-N 3.39Å
207	K	43.4	Very low	48.8	Very low	142 Å²	142	100.6 Å²	100.6	62%	0.617	57%	0.567	S	S	*	*	H	α-helix	trans	-73.1	-38.9	177.1	-93.1	-177.1	173	-178.2	0	112.3	K204 I205 L211	K204-K207 PolarHBondContact O-N 3Å; I205-K207 VanDerWaalsContact C-N 3.32Å; I205-K207 PolarHBondContact O-N 3.3Å; K207-L211 WeakPolarHBondContact O-CB 3.23Å; K207-L211 VanDerWaalsContact O-CD1 3.3Å; K207-L211 WeakPolarHBondContact O-CD1 2.94Å; K207-L211 WeakPolarHBondContact O-CG 3.14Å; K207-L211 PolarHBondContact O-N 2.85Å
208	D	44	Very low	46.6	Very low	99 Å²	99	103.4 Å²	103.4	53%	0.529	58%	0.583	S	S	.	*	H	α-helix	trans	-75.4	-37.4	178.7	-65.9	-28.3	0	0	0	111.3	K204 I205 L211 V212	K204-D208 PolarHBondContact O-N 3.34Å; I205-D208 PolarHBondContact O-N 3.46Å; D208-L211 PolarHBondContact O-N 2.97Å; D208-V212 WeakPolarHBondContact O-CB 3.16Å; D208-V212 WeakPolarHBondContact O-CG2 3.43Å; D208-V212 PolarHBondContact O-N 3.32Å
209	E	44.9	Very low	44.8	Very low	120 Å²	120	109.9 Å²	109.9	56%	0.561	61%	0.609	S	S	*	*	H	α-helix	trans	-67.8	-40.8	168.9	-76.5	-177.5	158.7	0	0	111.6	I205 L211 V212 V213	I205-E209 HydrophobicContact CG2-CG 4.17Å; I205-E209 VanDerWaalsContact O-CB 3.25Å; I205-E209 WeakPolarHBondContact O-CB 3.36Å; I205-E209 WeakPolarHBondContact O-CG 3.25Å; I205-E209 PolarHBondContact O-N 3.35Å; E209-L211 VanDerWaalsContact C-N 3.34Å; E209-L211 PolarHBondContact O-N 3.27Å; E209-V212 PolarHBondContact O-N 3.22Å; E209-V213 WeakPolarHBondContact O-CB 3.33Å; E209-V213 WeakPolarHBondContact O-CG2 3.43Å; E209-V213 PolarHBondContact O-N 3.41Å
210	E	42.8	Very low	43	Very low	133 Å²	133	117.4 Å²	117.4	62%	0.621	63%	0.631	S	S	*	*	H	α-helix	trans	-65.6	-35	173.3	-81.6	175.3	160.2	0	0	112	K206 A214	K206-E210 WeakPolarHBondContact O-CB 3.35Å; K206-E210 WeakPolarHBondContact O-CG 3.36Å; K206-E210 PolarHBondContact O-N 3.39Å; E210-A214 WeakPolarHBondContact O-CB 3.24Å; E210-A214 PolarHBondContact O-N 2.9Å
211	L	44	Very low	41.8	Very low	115 Å²	115	123.7 Å²	123.7	60%	0.602	65%	0.65	S	S	*	*	H	α-helix	trans	-71.4	-32.7	176.1	-83.2	159.6	0	0	0	112.9	K207 D208 E209	K207-L211 WeakPolarHBondContact O-CB 3.23Å; K207-L211 VanDerWaalsContact O-CD1 3.3Å; K207-L211 WeakPolarHBondContact O-CD1 2.94Å; K207-L211 WeakPolarHBondContact O-CG 3.14Å; K207-L211 PolarHBondContact O-N 2.85Å; D208-L211 PolarHBondContact O-N 2.97Å; E209-L211 VanDerWaalsContact C-N 3.34Å; E209-L211 PolarHBondContact O-N 3.27Å
212	V	45.3	Very low	40.7	Very low	103 Å²	103	127.5 Å²	127.5	62%	0.624	66%	0.66	S	S	*	*	H	α-helix	trans	-82.3	-38.6	176.5	175.8	0	0	0	0	111.3	D208 E209 K215	D208-V212 WeakPolarHBondContact O-CB 3.16Å; D208-V212 WeakPolarHBondContact O-CG2 3.43Å; D208-V212 PolarHBondContact O-N 3.32Å; E209-V212 PolarHBondContact O-N 3.22Å; V212-K215 PolarHBondContact O-N 2.85Å
213	V	45	Very low	39.7	Very low	90 Å²	90	129.8 Å²	129.8	55%	0.545	68%	0.678	S	S	.	*	H	α-helix	trans	-74.7	-31.4	177.8	174.8	0	0	0	0	112	E209 K215 T216 A217	E209-V213 WeakPolarHBondContact O-CB 3.33Å; E209-V213 WeakPolarHBondContact O-CG2 3.43Å; E209-V213 PolarHBondContact O-N 3.41Å; V213-K215 PolarHBondContact O-N 3.26Å; V213-K215 VanDerWaalsContact O-N 3.14Å; V213-T216 PolarHBondContact O-N 3.47Å; V213-T216 VanDerWaalsContact O-N 3.13Å; V213-A217 PolarHBondContact O-N 2.95Å
214	A	38.2	Very low	39.1	Very low	88 Å²	88	133.1 Å²	133.1	73%	0.727	69%	0.688	S	S	*	*	T	Hydrogen-bonded Turn	trans	-64.4	-14.7	174.5	0	0	0	0	0	113.8	E210	E210-A214 WeakPolarHBondContact O-CB 3.24Å; E210-A214 PolarHBondContact O-N 2.9Å
215	K	38.6	Very low	38.7	Very low	187 Å²	187	131.6 Å²	131.6	81%	0.813	69%	0.69	S	S	*	*	T	Hydrogen-bonded Turn	trans	-91	-5	175.1	-74.4	-173.8	175.4	-178.3	0	114.4	V212 V213	V212-K215 PolarHBondContact O-N 2.85Å; V213-K215 PolarHBondContact O-N 3.26Å; V213-K215 VanDerWaalsContact O-N 3.14Å
216	T	35.2	Very low	38.5	Very low	124 Å²	124	133.5 Å²	133.5	76%	0.761	71%	0.708	S	S	*	*	T	Hydrogen-bonded Turn	trans	-139.8	0.9	-171.6	-33.9	0	0	0	0	116.7	V213	V213-T216 PolarHBondContact O-N 3.47Å; V213-T216 VanDerWaalsContact O-N 3.13Å
217	A	31.9	Very low	38	Very low	70 Å²	70	133.3 Å²	133.3	58%	0.579	71%	0.713	S	S	*	*			trans	-146.4	89.7	179	0	0	0	0	0	115.5	V213 K219	V213-A217 PolarHBondContact O-N 2.95Å; A217-K219 PolarHBondContact O-N 3.33Å
218	T	35.5	Very low	37.8	Very low	148 Å²	148	128.1 Å²	128.1	91%	0.908	70%	0.7	S	S	*	*			trans	-69.2	90.9	144.3	14.3	0	0	0	0	108.6
219	K	31.8	Very low	37.9	Very low	197 Å²	197	126.3 Å²	126.3	86%	0.857	69%	0.692	S	S	*	*			trans	-169.8	122.2	154.4	-109.3	164.8	-173.1	-179.1	0	112.7	A217	A217-K219 PolarHBondContact O-N 3.33Å
220	K	27.1	Very low	38.2	Very low	194 Å²	194	124.1 Å²	124.1	84%	0.843	69%	0.687	S	S	*	*			trans	41.8	102	162.6	-86.2	-179.1	171	-178.9	0	118.4	E222	K220-E222 PolarHBondContact O-N 2.94Å
221	K	29.3	Very low	38.4	Very low	213 Å²	213	123 Å²	123	93%	0.926	69%	0.685	S	S	*	*			trans	-65.8	103.4	154.3	-109.2	177.2	175.3	174.6	0	109.1
222	E	32.3	Very low	38.8	Very low	169 Å²	169	126.4 Å²	126.4	79%	0.79	70%	0.695	S	S	*	*			trans	-82.4	120.3	158	-81.3	-174.4	168.1	0	0	108.9	K220 T224	K220-E222 PolarHBondContact O-N 2.94Å; E222-T224 PolarHBondContact O-N 2.95Å
223	T	32.4	Very low	39.2	Very low	134 Å²	134	125.8 Å²	125.8	82%	0.822	68%	0.684	S	S	*	*			trans	-62.9	99.4	171.6	42.7	0	0	0	0	109.6	T225	T223-T225 PolarHBondContact O-N 3.39Å; T223-T225 VanDerWaalsContact O-N 3.13Å
224	T	36.4	Very low	40.1	Very low	123 Å²	123	123.3 Å²	123.3	76%	0.755	67%	0.667	S	S	*	*			trans	-76.6	99.7	174.1	9.2	0	0	0	0	108.9	E222	E222-T224 PolarHBondContact O-N 2.95Å
225	T	37.5	Very low	41.6	Very low	100 Å²	100	121.6 Å²	121.6	61%	0.613	65%	0.646	S	S	*	*			trans	-58.7	152.6	168	32.8	0	0	0	0	110.8	T223 L227 G228	T223-T225 PolarHBondContact O-N 3.39Å; T223-T225 VanDerWaalsContact O-N 3.13Å; T225-L227 PolarHBondContact O-N 3.4Å; T225-G228 PolarHBondContact O-N 2.98Å
226	C	44.5	Very low	43.4	Very low	111 Å²	111	117.2 Å²	117.2	75%	0.75	63%	0.631	S	S	*	*	H	α-helix	trans	-49.4	-32.4	178.8	-148.8	0	0	0	0	112.6	G228 T229 V230	C226-G228 PolarHBondContact O-N 3.08Å; C226-T229 PolarHBondContact O-N 3.08Å; C226-V230 PolarHBondContact O-N 3.47Å
227	L	37.6	Very low	45.5	Very low	140 Å²	140	113.4 Å²	113.4	73%	0.733	61%	0.61	S	S	*	*	H	α-helix	trans	-61.3	-36.6	174	-116.3	81.2	0	0	0	114.2	T225 T229 V230 N231	T225-L227 PolarHBondContact O-N 3.4Å; L227-T229 VanDerWaalsContact C-N 3.27Å; L227-T229 PolarHBondContact O-N 3Å; L227-V230 PolarHBondContact O-N 3.49Å; L227-N231 WeakPolarHBondContact O-CB 3.45Å; L227-N231 PolarHBondContact O-N 2.9Å
228	G	39.3	Very low	47.8	Very low	32 Å²	32	110.2 Å²	110.2	33%	0.33	58%	0.583	S	S	.	*	H	α-helix	trans	-68.6	-27.6	178.2	0	0	0	0	0	112.9	T225 C226 K232	T225-G228 PolarHBondContact O-N 2.98Å; C226-G228 PolarHBondContact O-N 3.08Å; G228-K232 PolarHBondContact O-N 2.94Å
229	T	46.1	Very low	50.2	Low	62 Å²	62	106.9 Å²	106.9	38%	0.38	56%	0.556	S	S	.	*	H	α-helix	trans	-73.5	-41.8	172.7	-56.4	0	0	0	0	110.5	C226 L227 N231 K232 F233	C226-T229 PolarHBondContact O-N 3.08Å; L227-T229 VanDerWaalsContact C-N 3.27Å; L227-T229 PolarHBondContact O-N 3Å; T229-N231 PolarHBondContact O-N 3.22Å; T229-K232 WeakPolarHBondContact O-CB 3.5Å; T229-K232 PolarHBondContact O-N 3.34Å; T229-F233 HydrophobicContact CG2-CD2 4.16Å; T229-F233 HydrophobicContact CG2-CE2 3.91Å; T229-F233 WeakPolarHBondContact O-CD2 3.2Å; T229-F233 PolarHBondContact O-N 2.99Å
230	V	50.6	Low	52.6	Low	73 Å²	73	106.4 Å²	106.4	44%	0.442	55%	0.554	S	S	.	*	H	α-helix	trans	-62.9	-41	174.9	178	0	0	0	0	111.5	C226 L227 K232 F233 I234	C226-V230 PolarHBondContact O-N 3.47Å; L227-V230 PolarHBondContact O-N 3.49Å; V230-K232 PolarHBondContact O-N 3.36Å; V230-F233 PolarHBondContact O-N 3.27Å; V230-I234 HydrophobicContact CG1-CD1 3.75Å; V230-I234 HydrophobicContact CG1-CG1 4.29Å; V230-I234 PolarHBondContact O-N 2.98Å
231	N	47.1	Very low	55.3	Low	110 Å²	110	101.2 Å²	101.2	59%	0.588	53%	0.532	S	S	*	.	H	α-helix	trans	-67.1	-19.9	177.7	-151.3	34.6	0	0	0	113.2	L227 T229	L227-N231 WeakPolarHBondContact O-CB 3.45Å; L227-N231 PolarHBondContact O-N 2.9Å; T229-N231 PolarHBondContact O-N 3.22Å
232	K	52.6	Low	58.1	Low	186 Å²	186	97.9 Å²	97.9	81%	0.809	51%	0.514	S	S	*	.	H	α-helix	trans	-81.4	-21.7	173.4	-154.9	175.9	-175.8	177.6	0	112.7	G228 T229 V230	G228-K232 PolarHBondContact O-N 2.94Å; T229-K232 WeakPolarHBondContact O-CB 3.5Å; T229-K232 PolarHBondContact O-N 3.34Å; V230-K232 PolarHBondContact O-N 3.36Å
233	F	54.3	Low	60.7	Low	90 Å²	90	89.9 Å²	89.9	40%	0.395	48%	0.477	S	S	.	.	H	α-helix	trans	-100.3	-24	179.3	-75.7	-71.7	0	0	0	113.8	V78 N81 T229 V230 S370	V78-F233 HydrophobicContact CG2-CD2 4.39Å; V78-F233 HydrophobicContact CG2-CE2 4.43Å; N81-F233 WeakPolarHBondContact ND2-CE1 3.37Å; N81-F233 VanDerWaalsContact ND2-CZ 3.3Å; N81-F233 WeakPolarHBondContact ND2-CZ 3.35Å; T229-F233 HydrophobicContact CG2-CD2 4.16Å; T229-F233 HydrophobicContact CG2-CE2 3.91Å; T229-F233 WeakPolarHBondContact O-CD2 3.2Å; T229-F233 PolarHBondContact O-N 2.99Å; V230-F233 PolarHBondContact O-N 3.27Å; F233-S370 PolarHBondContact O-OG 3.22Å
234	I	63.8	Low	63.4	Low	38 Å²	38	83.5 Å²	83.5	20%	0.195	44%	0.438	C	S	.	.	S	Bend	trans	-109.6	92.9	176.9	-55.3	-179	0	0	0	107.9	V230 L236 L374 I377	V230-I234 HydrophobicContact CG1-CD1 3.75Å; V230-I234 HydrophobicContact CG1-CG1 4.29Å; V230-I234 PolarHBondContact O-N 2.98Å; I234-L236 VanDerWaalsContact C-N 3.28Å; I234-L236 HydrophobicContact CG2-CD2 3.73Å; I234-L236 HydrophobicContact CG2-CG 4.12Å; I234-L236 PolarHBondContact O-N 3.1Å; I234-L374 HydrophobicContact CG2-CD1 3.94Å; I234-I377 HydrophobicContact CD1-CD1 4.06Å
235	D	70.4	Confident	66	Low	52 Å²	52	81.8 Å²	81.8	28%	0.278	42%	0.424	S	S	.	.			trans	-73.2	84.8	174.7	-174.4	2.4	0	0	0	109.6	S237 L238 S370	D235-S237 PolarHBondContact O-N 3.05Å; D235-S237 WeakPolarHBondContact OD1-CB 3.37Å; D235-S237 PolarHBondContact OD1-N 3.14Å; D235-S237 VanDerWaalsContact OD1-N 3.12Å; D235-S237 PolarHBondContact OD1-OG 3.36Å; D235-S237 PolarHBondContact OD2-OG 2.78Å; D235-L238 HydrophobicContact CB-CD1 4.15Å; D235-L238 HydrophobicContact CB-CG 4.49Å; D235-L238 VanDerWaalsContact O-CB 3.3Å; D235-L238 WeakPolarHBondContact O-CB 3.3Å; D235-L238 WeakPolarHBondContact O-CD1 3.3Å; D235-L238 WeakPolarHBondContact O-CG 3.47Å; D235-L238 PolarHBondContact O-N 2.96Å; D235-S370 VanDerWaalsContact CB-OG 3.23Å; D235-S370 WeakPolarHBondContact CB-OG 3.42Å; D235-S370 PolarHBondContact N-OG 3.2Å
236	L	75.4	Confident	68.5	Low	96 Å²	96	78.6 Å²	78.6	50%	0.503	40%	0.402	S	S	.	.	G	3₁₀ helix	trans	-59.8	-12.6	178.2	-66.9	174.8	0	0	0	112.8	I234 L238 F239	I234-L236 VanDerWaalsContact C-N 3.28Å; I234-L236 HydrophobicContact CG2-CD2 3.73Å; I234-L236 HydrophobicContact CG2-CG 4.12Å; I234-L236 PolarHBondContact O-N 3.1Å; L236-L238 PolarHBondContact O-N 2.95Å; L236-F239 HydrophobicContact CD2-CD2 3.89Å; L236-F239 HydrophobicContact CD2-CE2 3.69Å; L236-F239 PolarHBondContact O-N 3.4Å
237	S	79.1	Confident	70.8	Confident	44 Å²	44	73.8 Å²	73.8	31%	0.308	37%	0.368	S	S	.	.	G	3₁₀ helix	trans	-63.2	-21.1	171.5	82.9	0	0	0	0	112.5	D235 F239 K240 R367	D235-S237 PolarHBondContact O-N 3.05Å; D235-S237 WeakPolarHBondContact OD1-CB 3.37Å; D235-S237 PolarHBondContact OD1-N 3.14Å; D235-S237 VanDerWaalsContact OD1-N 3.12Å; D235-S237 PolarHBondContact OD1-OG 3.36Å; D235-S237 PolarHBondContact OD2-OG 2.78Å; S237-F239 PolarHBondContact O-N 2.74Å; S237-K240 WeakPolarHBondContact O-CB 3.27Å; S237-K240 PolarHBondContact O-N 2.76Å; S237-R367 PolarHBondContact OG-NH1 3.46Å
238	L	81.4	Confident	73.5	Confident	3 Å²	3	67.5 Å²	67.5	2%	0.016	34%	0.336	C	S	.	.	G	3₁₀ helix	trans	-60	-30.6	174.5	-76.1	161.1	0	0	0	112.8	D235 L236 K240 H241 F244 V363 R367 A371 L374	D235-L238 HydrophobicContact CB-CD1 4.15Å; D235-L238 HydrophobicContact CB-CG 4.49Å; D235-L238 VanDerWaalsContact O-CB 3.3Å; D235-L238 WeakPolarHBondContact O-CB 3.3Å; D235-L238 WeakPolarHBondContact O-CD1 3.3Å; D235-L238 WeakPolarHBondContact O-CG 3.47Å; D235-L238 PolarHBondContact O-N 2.96Å; L236-L238 PolarHBondContact O-N 2.95Å; L238-K240 PolarHBondContact O-N 3.32Å; L238-H241 WeakPolarHBondContact O-CB 3.43Å; L238-H241 PolarHBondContact O-N 3.43Å; L238-F244 HydrophobicContact CB-CD1 4.04Å; L238-F244 HydrophobicContact CB-CE1 4.04Å; L238-F244 VanDerWaalsContact O-CD1 3.31Å; L238-F244 WeakPolarHBondContact O-CD1 3.26Å; L238-V363 HydrophobicContact CD2-CB 4.5Å; L238-V363 HydrophobicContact CD2-CG1 3.55Å; L238-V363 HydrophobicContact CD2-CG2 4.11Å; L238-R367 HydrophobicContact CD2-CB 4.43Å; L238-A371 HydrophobicContact CD1-CB 3.92Å; L238-A371 HydrophobicContact CD2-CB 4.3Å; L238-L374 HydrophobicContact CB-CD2 4.26Å
239	F	84.9	Confident	76.1	Confident	78 Å²	78	67.9 Å²	67.9	34%	0.342	33%	0.333	S	S	.	.	G	3₁₀ helix	trans	-66.9	-16.5	175.8	-74.2	-65.8	0	0	0	113.6	L236 S237 H241 F244 L245 L248 L374	L236-F239 HydrophobicContact CD2-CD2 3.89Å; L236-F239 HydrophobicContact CD2-CE2 3.69Å; L236-F239 PolarHBondContact O-N 3.4Å; S237-F239 PolarHBondContact O-N 2.74Å; F239-H241 VanDerWaalsContact C-N 3.32Å; F239-F244 HydrophobicContact CD1-CE1 4.47Å; F239-L245 HydrophobicContact CD1-CD1 4.18Å; F239-L248 HydrophobicContact CD1-CD2 4.32Å; F239-L248 HydrophobicContact CE1-CD2 3.56Å; F239-L248 HydrophobicContact CZ-CD2 4.42Å; F239-L374 HydrophobicContact CD2-CD2 4.03Å; F239-L374 HydrophobicContact CE1-CD2 4.21Å; F239-L374 HydrophobicContact CE2-CD1 3.7Å; F239-L374 HydrophobicContact CE2-CD2 3.55Å; F239-L374 HydrophobicContact CE2-CG 4.12Å; F239-L374 HydrophobicContact CZ-CD1 3.64Å; F239-L374 HydrophobicContact CZ-CD2 3.66Å; F239-L374 HydrophobicContact CZ-CG 3.91Å
240	K	82.1	Confident	78.4	Confident	186 Å²	186	65 Å²	65	81%	0.809	32%	0.315	S	S	*	.	G	3₁₀ helix	trans	-80.3	-16.1	172.2	-60	-175.6	178.3	-177.2	0	112.4	S237 L238 R242	S237-K240 WeakPolarHBondContact O-CB 3.27Å; S237-K240 PolarHBondContact O-N 2.76Å; L238-K240 PolarHBondContact O-N 3.32Å; K240-R242 PolarHBondContact O-N 3.24Å
241	H	84.6	Confident	80.5	Confident	86 Å²	86	61.5 Å²	61.5	40%	0.398	29%	0.294	S	S	.	.			trans	-79.7	109.4	-179	-168.8	-99.3	0	0	0	110.4	L238 F239 G243 F244 L245 L362	L238-H241 WeakPolarHBondContact O-CB 3.43Å; L238-H241 PolarHBondContact O-N 3.43Å; F239-H241 VanDerWaalsContact C-N 3.32Å; H241-G243 VanDerWaalsContact C-N 3.3Å; H241-G243 PolarHBondContact O-N 3.38Å; H241-F244 HydrophobicContact CB-CB 4.02Å; H241-F244 PolarHBondContact ND1-N 3.41Å; H241-F244 WeakPolarHBondContact O-CB 3.4Å; H241-F244 PolarHBondContact O-N 3.43Å; H241-L245 PolarHBondContact O-N 2.91Å; H241-L245 VanDerWaalsContact O-N 3.09Å; H241-L362 PolarHBondContact CE1-O 3.31Å; H241-L362 VanDerWaalsContact CE1-O 3.24Å
242	R	86.8	Confident	82.7	Confident	142 Å²	142	58.4 Å²	58.4	54%	0.536	28%	0.279	S	S	.	.	H	α-helix	trans	-52.1	-47.1	-174.7	-62.6	179.1	-176.9	157.8	2.6	112.6	K240 F244 L245 I246 E432	K240-R242 PolarHBondContact O-N 3.24Å; R242-F244 VanDerWaalsContact C-N 3.35Å; R242-F244 PolarHBondContact O-N 2.94Å; R242-L245 PolarHBondContact O-N 2.74Å; R242-I246 WeakPolarHBondContact O-CG1 3.32Å; R242-I246 PolarHBondContact O-N 3.15Å; R242-I246 VanDerWaalsContact O-N 3.15Å; R242-E432 IonicContact CZ-OE1 3Å; R242-E432 IonicContact NH1-OE1 2.7Å; R242-E432 PolarHBondContact NH1-OE1 3.03Å
243	G	86.8	Confident	84.8	Confident	1 Å²	1	52.5 Å²	52.5	1%	0.01	26%	0.256	C	S	.	.	H	α-helix	trans	-61.2	-43.1	179.3	0	0	0	0	0	112.5	H241 L245 I246 Y247 L362	H241-G243 VanDerWaalsContact C-N 3.3Å; H241-G243 PolarHBondContact O-N 3.38Å; G243-L245 VanDerWaalsContact C-N 3.32Å; G243-L245 PolarHBondContact O-N 3.21Å; G243-I246 PolarHBondContact O-N 3.06Å; G243-Y247 PolarHBondContact O-N 3.23Å; G243-L362 WeakPolarHBondContact O-CD2 3.49Å
244	F	89.3	Confident	86.7	Confident	0 Å²	0	48.2 Å²	48.2	0%	0	24%	0.237	C	C	.	.	H	α-helix	trans	-64.6	-37.9	179.8	176.8	-102.3	0	0	0	111.5	L238 F239 H241 R242 Y247 L248 L359 L362 V363 A371 L374 T375	L238-F244 HydrophobicContact CB-CD1 4.04Å; L238-F244 HydrophobicContact CB-CE1 4.04Å; L238-F244 VanDerWaalsContact O-CD1 3.31Å; L238-F244 WeakPolarHBondContact O-CD1 3.26Å; F239-F244 HydrophobicContact CD1-CE1 4.47Å; H241-F244 HydrophobicContact CB-CB 4.02Å; H241-F244 PolarHBondContact ND1-N 3.41Å; H241-F244 WeakPolarHBondContact O-CB 3.4Å; H241-F244 PolarHBondContact O-N 3.43Å; R242-F244 VanDerWaalsContact C-N 3.35Å; R242-F244 PolarHBondContact O-N 2.94Å; F244-Y247 PolarHBondContact O-N 2.97Å; F244-L248 HydrophobicContact CE1-CD2 4.07Å; F244-L248 HydrophobicContact CZ-CD2 4.39Å; F244-L248 VanDerWaalsContact O-CB 3.24Å; F244-L248 WeakPolarHBondContact O-CB 3.31Å; F244-L248 PolarHBondContact O-N 3.33Å; F244-L359 HydrophobicContact CD2-CD1 3.9Å; F244-L359 HydrophobicContact CE2-CD1 3.88Å; F244-L362 HydrophobicContact CB-CD2 4.39Å; F244-V363 HydrophobicContact CB-CG2 4.36Å; F244-V363 HydrophobicContact CD2-CG2 3.79Å; F244-V363 HydrophobicContact CG-CG2 4.41Å; F244-A371 HydrophobicContact CD2-CB 4.49Å; F244-A371 HydrophobicContact CE2-CB 3.96Å; F244-L374 HydrophobicContact CE1-CD2 3.7Å; F244-L374 HydrophobicContact CE1-CG 4.46Å; F244-L374 HydrophobicContact CZ-CB 4.45Å; F244-L374 HydrophobicContact CZ-CD2 3.82Å; F244-L374 HydrophobicContact CZ-CG 4.22Å; F244-T375 WeakPolarHBondContact CE2-OG1 3.29Å
245	L	91	Very high	88.2	Confident	88 Å²	88	46.7 Å²	46.7	46%	0.461	23%	0.229	S	C	.	.	H	α-helix	trans	-66.9	-39.5	177.9	-163.4	70.7	0	0	0	112.6	F239 H241 R242 G243 S249	F239-L245 HydrophobicContact CD1-CD1 4.18Å; H241-L245 PolarHBondContact O-N 2.91Å; H241-L245 VanDerWaalsContact O-N 3.09Å; R242-L245 PolarHBondContact O-N 2.74Å; G243-L245 VanDerWaalsContact C-N 3.32Å; G243-L245 PolarHBondContact O-N 3.21Å; L245-S249 WeakPolarHBondContact O-CB 3.25Å; L245-S249 PolarHBondContact O-N 3.3Å; L245-S249 PolarHBondContact O-OG 3.43Å
246	I	91.6	Very high	89.3	Confident	32 Å²	32	47.2 Å²	47.2	16%	0.164	23%	0.232	C	C	.	.	H	α-helix	trans	-63.5	-47.1	174.2	-68.1	163	0	0	0	110.3	R242 G243 S249 G250 N425	R242-I246 WeakPolarHBondContact O-CG1 3.32Å; R242-I246 PolarHBondContact O-N 3.15Å; R242-I246 VanDerWaalsContact O-N 3.15Å; G243-I246 PolarHBondContact O-N 3.06Å; I246-S249 PolarHBondContact O-OG 3.01Å; I246-G250 PolarHBondContact O-N 3.02Å; I246-N425 HydrophobicContact CD1-CB 4.07Å
247	Y	92.5	Very high	90.1	Very high	10 Å²	10	42.7 Å²	42.7	4%	0.039	21%	0.208	C	C	.	.	H	α-helix	trans	-59.1	-49.3	176.5	174.9	-91.4	0	0	0	111.7	G243 F244 G250 N251 F314 L355 T358 L359 L362 T375	G243-Y247 PolarHBondContact O-N 3.23Å; F244-Y247 PolarHBondContact O-N 2.97Å; Y247-G250 PolarHBondContact O-N 3.49Å; Y247-N251 WeakPolarHBondContact CE1-ND2 3.39Å; Y247-N251 WeakPolarHBondContact O-CB 3.44Å; Y247-N251 PolarHBondContact O-N 3.3Å; Y247-N251 PolarHBondContact OH-ND2 2.91Å; Y247-F314 HydrophobicContact CE2-CE1 4.22Å; Y247-L355 WeakPolarHBondContact OH-CD1 3.41Å; Y247-L355 PolarHBondContact OH-O 3.06Å; Y247-T358 WeakPolarHBondContact CE2-OG1 3.22Å; Y247-L359 HydrophobicContact CD1-CD1 4.02Å; Y247-L359 HydrophobicContact CE1-CB 4.2Å; Y247-L359 HydrophobicContact CE1-CD1 3.78Å; Y247-L359 HydrophobicContact CE1-CD2 4.44Å; Y247-L359 HydrophobicContact CE1-CG 4.36Å; Y247-L362 HydrophobicContact CG-CD2 4.04Å; Y247-T375 HydrophobicContact CE1-CG2 4.25Å
248	L	93.1	Very high	90.8	Very high	9 Å²	9	40.9 Å²	40.9	5%	0.047	20%	0.195	C	C	.	.	H	α-helix	trans	-63	-46	-178.6	-173	67.5	0	0	0	112	F239 F244 G250 N251 V252 T375 V378	F239-L248 HydrophobicContact CD1-CD2 4.32Å; F239-L248 HydrophobicContact CE1-CD2 3.56Å; F239-L248 HydrophobicContact CZ-CD2 4.42Å; F244-L248 HydrophobicContact CE1-CD2 4.07Å; F244-L248 HydrophobicContact CZ-CD2 4.39Å; F244-L248 VanDerWaalsContact O-CB 3.24Å; F244-L248 WeakPolarHBondContact O-CB 3.31Å; F244-L248 PolarHBondContact O-N 3.33Å; L248-G250 PolarHBondContact O-N 3.3Å; L248-N251 PolarHBondContact O-N 3.08Å; L248-V252 WeakPolarHBondContact O-CG2 3.3Å; L248-V252 PolarHBondContact O-N 2.88Å; L248-T375 HydrophobicContact CD1-CG2 4.32Å; L248-V378 HydrophobicContact CD1-CB 4.01Å; L248-V378 HydrophobicContact CD1-CG1 4.02Å; L248-V378 HydrophobicContact CD2-CG1 4.33Å; L248-V378 HydrophobicContact CD2-CG2 4.38Å; L248-V378 HydrophobicContact CG-CG1 4.19Å
249	S	94.4	Very high	91.2	Very high	40 Å²	40	41.2 Å²	41.2	28%	0.28	20%	0.196	S	C	.	.	H	α-helix	trans	-62.6	-41.7	178	56.3	0	0	0	0	112.2	L245 I246 V252 I253 W417	L245-S249 WeakPolarHBondContact O-CB 3.25Å; L245-S249 PolarHBondContact O-N 3.3Å; L245-S249 PolarHBondContact O-OG 3.43Å; I246-S249 PolarHBondContact O-OG 3.01Å; S249-V252 PolarHBondContact O-N 2.87Å; S249-I253 WeakPolarHBondContact O-CG1 3.4Å; S249-I253 PolarHBondContact O-N 3Å; S249-W417 PolarHBondContact OG-NE1 2.93Å
250	G	94.4	Very high	91.6	Very high	0 Å²	0	37.6 Å²	37.6	0%	0	18%	0.18	C	C	.	.	H	α-helix	trans	-65.7	-41.9	175.7	0	0	0	0	0	113.3	I246 Y247 L248 V252 I253 M254	I246-G250 PolarHBondContact O-N 3.02Å; Y247-G250 PolarHBondContact O-N 3.49Å; L248-G250 PolarHBondContact O-N 3.3Å; G250-V252 VanDerWaalsContact C-N 3.35Å; G250-V252 PolarHBondContact O-N 2.86Å; G250-I253 PolarHBondContact O-N 3.36Å; G250-M254 WeakPolarHBondContact O-CB 3.47Å; G250-M254 PolarHBondContact O-N 3.43Å
251	N	93.9	Very high	92.2	Very high	0 Å²	0	28.7 Å²	28.7	0%	0	14%	0.142	C	C	.	.	H	α-helix	trans	-60.8	-43	175.3	-81.8	13.4	0	0	0	111.8	Y247 L248 I253 M254 F255 E379	Y247-N251 WeakPolarHBondContact CE1-ND2 3.39Å; Y247-N251 WeakPolarHBondContact O-CB 3.44Å; Y247-N251 PolarHBondContact O-N 3.3Å; Y247-N251 PolarHBondContact OH-ND2 2.91Å; L248-N251 PolarHBondContact O-N 3.08Å; N251-I253 VanDerWaalsContact C-N 3.32Å; N251-I253 PolarHBondContact O-N 3.32Å; N251-M254 PolarHBondContact O-N 3.3Å; N251-F255 HydrophobicContact CB-CD2 4.12Å; N251-F255 HydrophobicContact CB-CE2 4.17Å; N251-F255 WeakPolarHBondContact O-CB 3.34Å; N251-F255 WeakPolarHBondContact O-CD2 3.43Å; N251-F255 PolarHBondContact O-N 3.45Å; N251-E379 PolarHBondContact ND2-OE1 2.94Å
252	V	95.1	Very high	92.6	Very high	46 Å²	46	24.7 Å²	24.7	28%	0.279	12%	0.123	S	C	.	.	H	α-helix	trans	-59	-44.2	178.5	169.2	0	0	0	0	111.7	L248 S249 G250 V378 P382	L248-V252 WeakPolarHBondContact O-CG2 3.3Å; L248-V252 PolarHBondContact O-N 2.88Å; S249-V252 PolarHBondContact O-N 2.87Å; G250-V252 VanDerWaalsContact C-N 3.35Å; G250-V252 PolarHBondContact O-N 2.86Å; V252-V378 HydrophobicContact CG2-CG1 3.55Å; V252-P382 HydrophobicContact CG1-CG 4.19Å; V252-P382 WeakPolarHBondContact O-CB 3.41Å
253	I	95.6	Very high	92.8	Very high	61 Å²	61	18.4 Å²	18.4	31%	0.313	10%	0.1	S	C	.	.	H	α-helix	trans	-66.2	-44.7	177.2	-58.9	167.3	0	0	0	110.1	S249 G250 N251 L256 V410 A414 W417	S249-I253 WeakPolarHBondContact O-CG1 3.4Å; S249-I253 PolarHBondContact O-N 3Å; G250-I253 PolarHBondContact O-N 3.36Å; N251-I253 VanDerWaalsContact C-N 3.32Å; N251-I253 PolarHBondContact O-N 3.32Å; I253-L256 WeakPolarHBondContact O-CB 3.44Å; I253-L256 PolarHBondContact O-N 3.09Å; I253-V410 HydrophobicContact CG2-CG1 4.22Å; I253-V410 VanDerWaalsContact O-CG1 3.22Å; I253-V410 WeakPolarHBondContact O-CG1 3.43Å; I253-A414 HydrophobicContact CB-CB 3.98Å; I253-A414 HydrophobicContact CG2-CB 3.79Å; I253-W417 HydrophobicContact CD1-CG 4.41Å
254	M	95.4	Very high	93.1	Very high	1 Å²	1	18.6 Å²	18.6	1%	0.005	10%	0.101	C	C	.	.	H	α-helix	trans	-59	-50.3	179.1	-179.5	-169.2	70.8	0	0	111.7	G250 N251 L256 G257 F258 F314 V318 V351 L355 A414	G250-M254 WeakPolarHBondContact O-CB 3.47Å; G250-M254 PolarHBondContact O-N 3.43Å; N251-M254 PolarHBondContact O-N 3.3Å; M254-L256 PolarHBondContact O-N 2.83Å; M254-L256 VanDerWaalsContact O-N 3.16Å; M254-G257 PolarHBondContact O-N 3.39Å; M254-G257 VanDerWaalsContact O-N 3.08Å; M254-F258 HydrophobicContact CG-CB 4.43Å; M254-F258 WeakPolarHBondContact O-CB 3.34Å; M254-F258 PolarHBondContact O-N 3.32Å; M254-F314 HydrophobicContact SD-CZ 4.29Å; M254-V318 HydrophobicContact CG-CG1 4Å; M254-V318 HydrophobicContact SD-CB 4.5Å; M254-V318 HydrophobicContact SD-CG1 4.02Å; M254-V318 HydrophobicContact SD-CG2 3.59Å; M254-V318 VanDerWaalsContact SD-CG2 3.59Å; M254-V351 HydrophobicContact CE-CG1 4.47Å; M254-V351 HydrophobicContact SD-CG1 4.13Å; M254-L355 HydrophobicContact CE-CD1 4.3Å; M254-A414 HydrophobicContact CB-CB 3.81Å
255	F	94.4	Very high	93.3	Very high	5 Å²	5	18.6 Å²	18.6	2%	0.022	10%	0.101	C	C	.	.	H	α-helix	trans	-65.3	-19.9	-174.2	-83.6	-64.5	0	0	0	114.1	N251 G257 F258 F259 L355 E379 P382 V383	N251-F255 HydrophobicContact CB-CD2 4.12Å; N251-F255 HydrophobicContact CB-CE2 4.17Å; N251-F255 WeakPolarHBondContact O-CB 3.34Å; N251-F255 WeakPolarHBondContact O-CD2 3.43Å; N251-F255 PolarHBondContact O-N 3.45Å; F255-G257 VanDerWaalsContact C-N 3.3Å; F255-G257 PolarHBondContact O-N 3.03Å; F255-F258 HydrophobicContact CD1-CB 4.39Å; F255-F258 HydrophobicContact CD1-CD1 4.1Å; F255-F258 AromaticContact CE1-CD1 3.95Å; F255-F258 HydrophobicContact CE1-CD1 3.95Å; F255-F258 HydrophobicContact CE1-CE1 4.41Å; F255-F259 AromaticContact CD1-CD2 3.86Å; F255-F259 HydrophobicContact CD1-CD2 3.86Å; F255-F259 AromaticContact CD1-CE2 3.35Å; F255-F259 HydrophobicContact CD1-CE2 3.35Å; F255-F259 HydrophobicContact CD1-CZ 4.25Å; F255-F259 HydrophobicContact CE1-CD2 4.38Å; F255-F259 AromaticContact CE1-CE2 3.47Å; F255-F259 HydrophobicContact CE1-CE2 3.47Å; F255-F259 VanDerWaalsContact CE1-CE2 3.47Å; F255-F259 AromaticContact CE1-CZ 3.93Å; F255-F259 HydrophobicContact CE1-CZ 3.93Å; F255-L355 HydrophobicContact CZ-CD2 4.1Å; F255-E379 HydrophobicContact CD2-CB 4.28Å; F255-E379 HydrophobicContact CD2-CG 3.66Å; F255-E379 HydrophobicContact CE2-CG 3.84Å; F255-E379 WeakPolarHBondContact CE2-OE1 3.38Å; F255-P382 HydrophobicContact CB-CB 4.14Å; F255-P382 HydrophobicContact CB-CG 3.96Å; F255-V383 HydrophobicContact CB-CG2 4.2Å; F255-V383 HydrophobicContact CD1-CG2 4.16Å; F255-V383 HydrophobicContact CG-CG2 4.36Å
256	L	93.9	Very high	93.3	Very high	64 Å²	64	14.5 Å²	14.5	34%	0.335	8%	0.08	S	C	.	.	H	α-helix	trans	-63.9	-37.2	173.9	-163.4	158.7	0	0	0	111.4	I253 M254 P382 G386 L389 V410	I253-L256 WeakPolarHBondContact O-CB 3.44Å; I253-L256 PolarHBondContact O-N 3.09Å; M254-L256 PolarHBondContact O-N 2.83Å; M254-L256 VanDerWaalsContact O-N 3.16Å; L256-P382 HydrophobicContact CB-CB 4.19Å; L256-G386 VanDerWaalsContact O-CA 3.27Å; L256-G386 WeakPolarHBondContact O-CA 3.32Å; L256-L389 HydrophobicContact CD2-CD2 4.42Å; L256-V410 HydrophobicContact CB-CG1 4.31Å; L256-V410 HydrophobicContact CD2-CG1 4.41Å
257	G	92.2	Very high	93.2	Very high	1 Å²	1	13.2 Å²	13.2	1%	0.01	7%	0.074	C	C	.	.	H	α-helix	trans	-104.2	-12	-179.8	0	0	0	0	0	115.4	M254 F255 P261	M254-G257 PolarHBondContact O-N 3.39Å; M254-G257 VanDerWaalsContact O-N 3.08Å; F255-G257 VanDerWaalsContact C-N 3.3Å; F255-G257 PolarHBondContact O-N 3.03Å; G257-P261 WeakPolarHBondContact O-CD 3.23Å
258	F	92.8	Very high	93.2	Very high	5 Å²	5	13 Å²	13	2%	0.022	7%	0.073	C	C	.	.	H	α-helix	trans	-74.5	-40.5	-169.6	-173.5	-112.1	0	0	0	114.4	M254 F255 F348 V351	M254-F258 HydrophobicContact CG-CB 4.43Å; M254-F258 WeakPolarHBondContact O-CB 3.34Å; M254-F258 PolarHBondContact O-N 3.32Å; F255-F258 HydrophobicContact CD1-CB 4.39Å; F255-F258 HydrophobicContact CD1-CD1 4.1Å; F255-F258 AromaticContact CE1-CD1 3.95Å; F255-F258 HydrophobicContact CE1-CD1 3.95Å; F255-F258 HydrophobicContact CE1-CE1 4.41Å; F258-F348 HydrophobicContact CD1-CE2 4.15Å; F258-F348 AromaticContact CE1-CD2 3.82Å; F258-F348 HydrophobicContact CE1-CD2 3.82Å; F258-F348 AromaticContact CE1-CE2 3.24Å; F258-F348 HydrophobicContact CE1-CE2 3.24Å; F258-F348 AromaticContact CE1-CZ 3.89Å; F258-F348 HydrophobicContact CE1-CZ 3.89Å; F258-F348 HydrophobicContact CE2-CD2 4.08Å; F258-F348 HydrophobicContact CE2-CE2 4.34Å; F258-F348 AromaticContact CZ-CD2 3.4Å; F258-F348 HydrophobicContact CZ-CD2 3.4Å; F258-F348 AromaticContact CZ-CE2 3.36Å; F258-F348 HydrophobicContact CZ-CE2 3.36Å; F258-F348 HydrophobicContact CZ-CG 4.23Å; F258-F348 HydrophobicContact CZ-CZ 4.15Å; F258-V351 HydrophobicContact CE2-CB 4.22Å; F258-V351 HydrophobicContact CE2-CG1 3.98Å; F258-V351 HydrophobicContact CE2-CG2 4.41Å; F258-V351 HydrophobicContact CZ-CB 4.23Å; F258-V351 HydrophobicContact CZ-CG1 3.93Å
259	F	91.1	Very high	93.1	Very high	11 Å²	11	12.6 Å²	12.6	5%	0.048	7%	0.071	C	C	.	.	S	Bend	trans	-90.1	-23.9	-175.2	-73.9	-68.2	0	0	0	114.2	L66 F255 I262 V263 F348 V383 P387	L66-F259 HydrophobicContact CD2-CD1 3.86Å; L66-F259 HydrophobicContact CD2-CD2 3.97Å; L66-F259 HydrophobicContact CD2-CE1 3.8Å; L66-F259 HydrophobicContact CD2-CE2 3.86Å; L66-F259 HydrophobicContact CD2-CG 3.96Å; L66-F259 HydrophobicContact CD2-CZ 3.79Å; F255-F259 AromaticContact CD1-CD2 3.86Å; F255-F259 HydrophobicContact CD1-CD2 3.86Å; F255-F259 AromaticContact CD1-CE2 3.35Å; F255-F259 HydrophobicContact CD1-CE2 3.35Å; F255-F259 HydrophobicContact CD1-CZ 4.25Å; F255-F259 HydrophobicContact CE1-CD2 4.38Å; F255-F259 AromaticContact CE1-CE2 3.47Å; F255-F259 HydrophobicContact CE1-CE2 3.47Å; F255-F259 VanDerWaalsContact CE1-CE2 3.47Å; F255-F259 AromaticContact CE1-CZ 3.93Å; F255-F259 HydrophobicContact CE1-CZ 3.93Å; F259-I262 HydrophobicContact CD1-CG2 4.26Å; F259-I262 WeakPolarHBondContact O-CG2 3.37Å; F259-I262 PolarHBondContact O-N 3.24Å; F259-V263 WeakPolarHBondContact O-CG2 3.4Å; F259-V263 PolarHBondContact O-N 2.76Å; F259-V263 VanDerWaalsContact O-N 3.1Å; F259-F348 HydrophobicContact CE1-CE2 4.45Å; F259-F348 HydrophobicContact CE1-CZ 4.39Å; F259-V383 HydrophobicContact CD2-CG1 4.4Å; F259-V383 HydrophobicContact CD2-CG2 3.83Å; F259-V383 HydrophobicContact CE2-CG2 3.73Å; F259-P387 HydrophobicContact CB-CG 4.49Å
260	S	93.3	Very high	92.9	Very high	1 Å²	1	11.6 Å²	11.6	1%	0.007	6%	0.062	C	C	.	.	H	α-helix	trans	-59.6	-45.7	-177	-45.3	0	0	0	0	112.9	I262 V263 F264 G386 P387	S260-I262 PolarHBondContact O-N 3.15Å; S260-V263 PolarHBondContact O-N 2.92Å; S260-F264 VanDerWaalsContact O-CD2 3.28Å; S260-F264 WeakPolarHBondContact O-CD2 3.43Å; S260-F264 PolarHBondContact O-N 3.41Å; S260-G386 VanDerWaalsContact OG-C 3.28Å; S260-G386 PolarHBondContact OG-O 3.01Å; S260-P387 WeakPolarHBondContact OG-CA 3.5Å
261	P	94.3	Very high	92.6	Very high	0 Å²	0	15.3 Å²	15.3	0%	0	8%	0.081	C	C	.	.	H	α-helix	trans	-58.6	-41.4	177.9	-30.8	41.1	0	0	0	114.3	G257 L265 H325 F344 Y404 C407	G257-P261 WeakPolarHBondContact O-CD 3.23Å; P261-L265 WeakPolarHBondContact O-CB 3.41Å; P261-L265 PolarHBondContact O-N 3.12Å; P261-L265 VanDerWaalsContact O-N 3.12Å; P261-H325 WeakPolarHBondContact CB-CE1 3.44Å; P261-F344 HydrophobicContact CB-CZ 4.46Å; P261-Y404 HydrophobicContact CB-CD1 4.1Å; P261-Y404 HydrophobicContact CB-CE1 3.67Å; P261-Y404 HydrophobicContact CG-CD1 4.42Å; P261-Y404 HydrophobicContact CG-CE1 4.44Å; P261-Y404 PolarHBondContact O-OH 3.4Å; P261-C407 HydrophobicContact CG-CB 3.8Å
262	I	92.4	Very high	92.3	Very high	1 Å²	1	18.3 Å²	18.3	1%	0.005	10%	0.097	C	C	.	.	H	α-helix	trans	-71	-34.3	178.3	-172.5	163.8	0	0	0	111.8	K38 F259 S260 L283 L286 F344	K38-I262 HydrophobicContact CD-CD1 3.77Å; K38-I262 HydrophobicContact CG-CD1 4.31Å; F259-I262 HydrophobicContact CD1-CG2 4.26Å; F259-I262 WeakPolarHBondContact O-CG2 3.37Å; F259-I262 PolarHBondContact O-N 3.24Å; S260-I262 PolarHBondContact O-N 3.15Å; I262-L283 HydrophobicContact CG1-CD2 4.04Å; I262-L286 HydrophobicContact CD1-CD1 4.2Å; I262-L286 HydrophobicContact CD1-CD2 4.08Å; I262-L286 HydrophobicContact CG1-CD1 4.4Å; I262-F344 HydrophobicContact CB-CE1 3.85Å; I262-F344 HydrophobicContact CB-CZ 3.88Å; I262-F344 HydrophobicContact CG1-CE1 4.42Å
263	V	92.4	Very high	92	Very high	10 Å²	10	19.3 Å²	19.3	6%	0.061	12%	0.116	C	C	.	.	H	α-helix	trans	-67.3	-43	178.4	168.9	0	0	0	0	111.5	T41 F44 F259 S260	T41-V263 WeakPolarHBondContact CB-O 3.17Å; T41-V263 HydrophobicContact CG2-CB 4.35Å; T41-V263 HydrophobicContact CG2-CG1 4Å; T41-V263 HydrophobicContact CG2-CG2 4.37Å; F44-V263 HydrophobicContact CD2-CG1 4.25Å; F44-V263 HydrophobicContact CE2-CG1 3.84Å; F259-V263 WeakPolarHBondContact O-CG2 3.4Å; F259-V263 PolarHBondContact O-N 2.76Å; F259-V263 VanDerWaalsContact O-N 3.1Å; S260-V263 PolarHBondContact O-N 2.92Å
264	F	92.6	Very high	91.8	Very high	5 Å²	5	17.4 Å²	17.4	2%	0.022	11%	0.107	C	C	.	.	H	α-helix	trans	-91.3	0.7	-176.8	-69	-69.2	0	0	0	114.6	A59 S260 T266 A267 Y268 P387 A390 G391 Y400 M403	A59-F264 HydrophobicContact CB-CE1 4.32Å; A59-F264 HydrophobicContact CB-CE2 4.31Å; A59-F264 HydrophobicContact CB-CZ 3.59Å; S260-F264 VanDerWaalsContact O-CD2 3.28Å; S260-F264 WeakPolarHBondContact O-CD2 3.43Å; S260-F264 PolarHBondContact O-N 3.41Å; F264-T266 PolarHBondContact O-N 3.47Å; F264-A267 PolarHBondContact O-N 3.02Å; F264-Y268 WeakPolarHBondContact O-CB 3.24Å; F264-Y268 PolarHBondContact O-N 3.34Å; F264-P387 HydrophobicContact CE2-CB 4.45Å; F264-P387 WeakPolarHBondContact CE2-O 3.44Å; F264-A390 HydrophobicContact CE2-CB 4.18Å; F264-G391 VanDerWaalsContact CZ-CA 3.47Å; F264-Y400 HydrophobicContact CB-CE1 4.29Å; F264-Y400 HydrophobicContact CD1-CE1 4.21Å; F264-Y400 HydrophobicContact CG-CE1 4.5Å; F264-M403 HydrophobicContact CB-CE 4.05Å; F264-M403 HydrophobicContact CB-SD 3.93Å; F264-M403 HydrophobicContact CD2-CE 4.4Å; F264-M403 HydrophobicContact CD2-SD 3.4Å; F264-M403 WeakPolarHBondContact CD2-SD 3.44Å; F264-M403 HydrophobicContact CE2-SD 4.06Å; F264-M403 HydrophobicContact CG-SD 3.82Å
265	L	92.6	Very high	91.6	Very high	0 Å²	0	21.4 Å²	21.4	0%	0	13%	0.129	C	C	.	.	H	α-helix	trans	-57.9	-47.6	-176.5	-177.1	56.8	0	0	0	113.1	P261 Y268 A269 L282 L283 L286 Y340	P261-L265 WeakPolarHBondContact O-CB 3.41Å; P261-L265 PolarHBondContact O-N 3.12Å; P261-L265 VanDerWaalsContact O-N 3.12Å; L265-Y268 PolarHBondContact O-N 3.39Å; L265-A269 PolarHBondContact O-N 3.38Å; L265-L282 HydrophobicContact CD2-CB 4.34Å; L265-L283 HydrophobicContact CB-CD2 4.5Å; L265-L283 HydrophobicContact CD2-CD2 4.16Å; L265-L286 HydrophobicContact CD2-CD1 4.12Å; L265-Y340 HydrophobicContact CD1-CD1 4.21Å; L265-Y340 HydrophobicContact CD1-CE1 3.8Å
266	T	91.6	Very high	91.4	Very high	3 Å²	3	24.3 Å²	24.3	2%	0.018	14%	0.142	C	C	.	.	H	α-helix	trans	-67	-41.3	179.5	51.5	0	0	0	0	111.6	T41 V42 F264 A269 K270 L283	T41-T266 PolarHBondContact O-OG1 3.32Å; V42-T266 HydrophobicContact CG2-CG2 4.27Å; F264-T266 PolarHBondContact O-N 3.47Å; T266-A269 PolarHBondContact O-N 3.17Å; T266-K270 WeakPolarHBondContact O-CB 3.45Å; T266-K270 WeakPolarHBondContact O-CG 3.46Å; T266-K270 PolarHBondContact O-N 3.44Å; T266-L283 HydrophobicContact CG2-CD1 3.37Å; T266-L283 HydrophobicContact CG2-CG 3.67Å
267	A	90.2	Very high	91.2	Very high	5 Å²	5	26.1 Å²	26.1	4%	0.041	15%	0.146	C	C	.	.	H	α-helix	trans	-63	-42.8	177.5	0	0	0	0	0	111.4	F264 K270 D271 Y400	F264-A267 PolarHBondContact O-N 3.02Å; A267-K270 PolarHBondContact O-N 3.44Å; A267-D271 WeakPolarHBondContact O-CB 3.47Å; A267-D271 PolarHBondContact O-N 2.82Å; A267-Y400 HydrophobicContact CB-CE1 4.45Å
268	Y	90.8	Very high	91.1	Very high	6 Å²	6	27.4 Å²	27.4	2%	0.024	15%	0.154	C	C	.	.	H	α-helix	trans	-63.6	-45.5	176	178.6	-127.3	0	0	0	112.5	F264 L265 K270 D271 I272 L337 Y400 Y404	F264-Y268 WeakPolarHBondContact O-CB 3.24Å; F264-Y268 PolarHBondContact O-N 3.34Å; L265-Y268 PolarHBondContact O-N 3.39Å; Y268-K270 PolarHBondContact O-N 3.29Å; Y268-D271 WeakPolarHBondContact O-CB 3.37Å; Y268-D271 PolarHBondContact O-N 2.84Å; Y268-I272 HydrophobicContact CD1-CD1 4.14Å; Y268-I272 HydrophobicContact CD2-CD1 4.08Å; Y268-I272 HydrophobicContact CD2-CG1 4.43Å; Y268-I272 HydrophobicContact CE1-CD1 3.67Å; Y268-I272 HydrophobicContact CE2-CD1 3.59Å; Y268-I272 HydrophobicContact CE2-CG1 4.05Å; Y268-I272 HydrophobicContact CG-CD1 4.35Å; Y268-I272 PolarHBondContact O-N 3.34Å; Y268-I272 VanDerWaalsContact O-N 3.1Å; Y268-L337 HydrophobicContact CD1-CD2 4.21Å; Y268-L337 HydrophobicContact CE1-CD2 3.91Å; Y268-Y400 HydrophobicContact CD2-CD1 4.47Å; Y268-Y400 AromaticContact CD2-CD2 3.83Å; Y268-Y400 HydrophobicContact CD2-CD2 3.83Å; Y268-Y400 AromaticContact CD2-CG 3.64Å; Y268-Y400 HydrophobicContact CD2-CG 3.64Å; Y268-Y400 HydrophobicContact CE2-CG 4.44Å; Y268-Y400 HydrophobicContact CG-CG 4.31Å; Y268-Y404 AromaticContact CD1-CE2 3.71Å; Y268-Y404 HydrophobicContact CD1-CE2 3.71Å; Y268-Y404 HydrophobicContact CD2-CE2 4.45Å; Y268-Y404 HydrophobicContact CE1-CE2 4.11Å; Y268-Y404 AromaticContact CG-CE2 3.87Å; Y268-Y404 HydrophobicContact CG-CE2 3.87Å
269	A	91.5	Very high	91.1	Very high	0 Å²	0	27.2 Å²	27.2	0%	0	15%	0.153	C	C	.	.	H	α-helix	trans	-60.8	-45.2	175.8	0	0	0	0	0	111.6	L265 T266 D271 I272 G273 V274 A279 L282 L337	L265-A269 PolarHBondContact O-N 3.38Å; T266-A269 PolarHBondContact O-N 3.17Å; A269-D271 PolarHBondContact O-N 3.34Å; A269-I272 PolarHBondContact O-N 3.1Å; A269-G273 PolarHBondContact O-N 3.36Å; A269-V274 HydrophobicContact CB-CB 4.31Å; A269-V274 HydrophobicContact CB-CG2 4.46Å; A269-V274 VanDerWaalsContact O-CB 3.25Å; A269-V274 WeakPolarHBondContact O-CB 3.43Å; A269-V274 WeakPolarHBondContact O-CG2 3.37Å; A269-V274 PolarHBondContact O-N 3.27Å; A269-V274 VanDerWaalsContact O-N 3.08Å; A269-A279 HydrophobicContact CB-CB 3.78Å; A269-L282 HydrophobicContact CB-CD1 3.61Å; A269-L337 HydrophobicContact CB-CD1 4.1Å
270	K	90.1	Very high	91.1	Very high	19 Å²	19	26.7 Å²	26.7	8%	0.083	15%	0.151	C	C	.	.	H	α-helix	trans	-63.6	-23.7	174.3	-70.4	-177.9	178.2	-174.2	0	112.4	V42 K45 D46 T266 A267 Y268 E276 A279	V42-K270 PolarHBondContact O-NZ 3.3Å; K45-K270 HydrophobicContact CB-CD 4.25Å; K45-K270 HydrophobicContact CD-CB 3.51Å; K45-K270 HydrophobicContact CD-CD 3.82Å; K45-K270 HydrophobicContact CD-CG 4.29Å; K45-K270 PolarHBondContact NZ-O 3.02Å; D46-K270 IonicContact OD2-NZ 3.08Å; D46-K270 PolarHBondContact OD2-NZ 2.98Å; T266-K270 WeakPolarHBondContact O-CB 3.45Å; T266-K270 WeakPolarHBondContact O-CG 3.46Å; T266-K270 PolarHBondContact O-N 3.44Å; A267-K270 PolarHBondContact O-N 3.44Å; Y268-K270 PolarHBondContact O-N 3.29Å; K270-E276 HydrophobicContact CD-CG 4.38Å; K270-A279 HydrophobicContact CG-CB 3.87Å
271	D	88.6	Confident	91.1	Very high	77 Å²	77	31.8 Å²	31.8	41%	0.412	17%	0.173	S	C	.	.	H	α-helix	trans	-78.8	-36.7	179.3	-167.7	61.8	0	0	0	112.4	A267 Y268 A269 G273 Y400	A267-D271 WeakPolarHBondContact O-CB 3.47Å; A267-D271 PolarHBondContact O-N 2.82Å; Y268-D271 WeakPolarHBondContact O-CB 3.37Å; Y268-D271 PolarHBondContact O-N 2.84Å; A269-D271 PolarHBondContact O-N 3.34Å; D271-G273 PolarHBondContact O-N 2.81Å; D271-Y400 HydrophobicContact CB-CD2 4.11Å; D271-Y400 HydrophobicContact CB-CE2 3.72Å; D271-Y400 WeakPolarHBondContact OD2-CD2 3.34Å
272	I	88.1	Confident	91.1	Very high	64 Å²	64	31.8 Å²	31.8	33%	0.328	17%	0.173	S	C	.	.	T	Hydrogen-bonded Turn	trans	-69.5	-10.1	172.1	-64.5	162.8	0	0	0	112.1	Y268 A269 L337	Y268-I272 HydrophobicContact CD1-CD1 4.14Å; Y268-I272 HydrophobicContact CD2-CD1 4.08Å; Y268-I272 HydrophobicContact CD2-CG1 4.43Å; Y268-I272 HydrophobicContact CE1-CD1 3.67Å; Y268-I272 HydrophobicContact CE2-CD1 3.59Å; Y268-I272 HydrophobicContact CE2-CG1 4.05Å; Y268-I272 HydrophobicContact CG-CD1 4.35Å; Y268-I272 PolarHBondContact O-N 3.34Å; Y268-I272 VanDerWaalsContact O-N 3.1Å; A269-I272 PolarHBondContact O-N 3.1Å; I272-L337 HydrophobicContact CD1-CD1 4.17Å
273	G	87.8	Confident	91.2	Very high	66 Å²	66	31.7 Å²	31.7	68%	0.68	17%	0.173	S	C	*	.	T	Hydrogen-bonded Turn	trans	94.4	16	179.6	0	0	0	0	0	114.3	A269 D271	A269-G273 PolarHBondContact O-N 3.36Å; D271-G273 PolarHBondContact O-N 2.81Å
274	V	91.2	Very high	91.3	Very high	21 Å²	21	31.6 Å²	31.6	13%	0.127	17%	0.173	C	C	.	.			trans	-68.3	142	170.5	-178	0	0	0	0	109.3	A269 Y334 L337	A269-V274 HydrophobicContact CB-CB 4.31Å; A269-V274 HydrophobicContact CB-CG2 4.46Å; A269-V274 VanDerWaalsContact O-CB 3.25Å; A269-V274 WeakPolarHBondContact O-CB 3.43Å; A269-V274 WeakPolarHBondContact O-CG2 3.37Å; A269-V274 PolarHBondContact O-N 3.27Å; A269-V274 VanDerWaalsContact O-N 3.08Å; V274-Y334 HydrophobicContact CG1-CD2 3.6Å; V274-Y334 HydrophobicContact CG1-CE2 3.97Å; V274-Y334 HydrophobicContact CG2-CD2 4.2Å; V274-L337 HydrophobicContact CG2-CD1 4.25Å
275	D	92.4	Very high	91.4	Very high	86 Å²	86	32.7 Å²	32.7	46%	0.46	18%	0.179	S	C	.	.			trans	-62.1	154	176.8	71.4	-87.1	0	0	0	112.2	Y277 S278 A279	D275-Y277 VanDerWaalsContact C-N 3.32Å; D275-Y277 PolarHBondContact O-N 3.13Å; D275-Y277 PolarHBondContact OD2-N 2.85Å; D275-S278 VanDerWaalsContact CG-CB 3.43Å; D275-S278 PolarHBondContact O-N 2.93Å; D275-S278 WeakPolarHBondContact OD1-CB 3.39Å; D275-S278 PolarHBondContact OD1-OG 3.08Å; D275-S278 VanDerWaalsContact OD2-CB 3.32Å; D275-S278 WeakPolarHBondContact OD2-CB 3.38Å; D275-S278 PolarHBondContact OD2-N 3.03Å; D275-S278 PolarHBondContact OD2-OG 3.03Å; D275-A279 WeakPolarHBondContact O-CB 3.16Å; D275-A279 PolarHBondContact O-N 3.37Å
276	E	88.9	Confident	91.6	Very high	65 Å²	65	32.8 Å²	32.8	30%	0.304	18%	0.179	S	C	.	.	H	α-helix	trans	-65.5	-34.5	-170.3	-56.6	-174.1	-179.3	0	0	113.3	Q166 K270 A280	Q166-E276 HydrophobicContact CG-CB 4.36Å; Q166-E276 PolarHBondContact NE2-OE2 3.39Å; K270-E276 HydrophobicContact CD-CG 4.38Å; E276-A280 PolarHBondContact O-N 3.18Å; E276-A280 VanDerWaalsContact O-N 3.09Å
277	Y	90.1	Very high	91.7	Very high	103 Å²	103	32.6 Å²	32.6	40%	0.404	18%	0.178	S	C	.	.	H	α-helix	trans	-70.4	-46.6	177.4	-85.2	-75.2	0	0	0	111.4	Q166 N170 D275 A279 A280 F281	Q166-Y277 HydrophobicContact CB-CD1 4.33Å; Q166-Y277 HydrophobicContact CB-CE1 4.34Å; Q166-Y277 HydrophobicContact CG-CD1 3.95Å; Q166-Y277 HydrophobicContact CG-CE1 4.1Å; Q166-Y277 HydrophobicContact CG-CG 4.19Å; N170-Y277 WeakPolarHBondContact ND2-CE2 3.41Å; D275-Y277 VanDerWaalsContact C-N 3.32Å; D275-Y277 PolarHBondContact O-N 3.13Å; D275-Y277 PolarHBondContact OD2-N 2.85Å; Y277-A279 VanDerWaalsContact C-N 3.3Å; Y277-A279 PolarHBondContact O-N 3.31Å; Y277-A280 PolarHBondContact O-N 2.99Å; Y277-F281 WeakPolarHBondContact O-CB 3.19Å; Y277-F281 PolarHBondContact O-N 3.21Å
278	S	91	Very high	91.9	Very high	28 Å²	28	37.9 Å²	37.9	20%	0.196	20%	0.2	C	C	.	.	H	α-helix	trans	-63.7	-35.5	176.5	-65.3	0	0	0	0	112	D275 F281 L282	D275-S278 VanDerWaalsContact CG-CB 3.43Å; D275-S278 PolarHBondContact O-N 2.93Å; D275-S278 WeakPolarHBondContact OD1-CB 3.39Å; D275-S278 PolarHBondContact OD1-OG 3.08Å; D275-S278 VanDerWaalsContact OD2-CB 3.32Å; D275-S278 WeakPolarHBondContact OD2-CB 3.38Å; D275-S278 PolarHBondContact OD2-N 3.03Å; D275-S278 PolarHBondContact OD2-OG 3.03Å; S278-F281 WeakPolarHBondContact O-CB 3.34Å; S278-F281 PolarHBondContact O-N 2.88Å; S278-L282 PolarHBondContact O-N 3.37Å
279	A	91.7	Very high	92.1	Very high	0 Å²	0	39 Å²	39	0%	0	21%	0.207	C	C	.	.	H	α-helix	trans	-64	-44.6	173.5	0	0	0	0	0	111.9	A269 K270 D275 Y277 F281 L282	A269-A279 HydrophobicContact CB-CB 3.78Å; K270-A279 HydrophobicContact CG-CB 3.87Å; D275-A279 WeakPolarHBondContact O-CB 3.16Å; D275-A279 PolarHBondContact O-N 3.37Å; Y277-A279 VanDerWaalsContact C-N 3.3Å; Y277-A279 PolarHBondContact O-N 3.31Å; A279-F281 VanDerWaalsContact C-N 3.28Å; A279-F281 PolarHBondContact O-N 2.97Å; A279-L282 WeakPolarHBondContact O-CB 3.46Å; A279-L282 PolarHBondContact O-N 3.26Å
280	A	91.4	Very high	92.2	Very high	1 Å²	1	39 Å²	39	1%	0.008	21%	0.208	C	C	.	.	H	α-helix	trans	-65.4	-33.3	173.8	0	0	0	0	0	112.1	V42 Q166 E276 Y277 L282 L283 S284	V42-A280 HydrophobicContact CG1-CB 4.36Å; V42-A280 HydrophobicContact CG2-CB 4.28Å; Q166-A280 HydrophobicContact CB-CB 4Å; Q166-A280 HydrophobicContact CG-CB 4.41Å; E276-A280 PolarHBondContact O-N 3.18Å; E276-A280 VanDerWaalsContact O-N 3.09Å; Y277-A280 PolarHBondContact O-N 2.99Å; A280-L282 VanDerWaalsContact C-N 3.26Å; A280-L282 PolarHBondContact O-N 3.4Å; A280-L283 PolarHBondContact O-N 3.49Å; A280-S284 PolarHBondContact O-OG 3.33Å
281	F	94.1	Very high	92.2	Very high	107 Å²	107	41.1 Å²	41.1	47%	0.469	22%	0.218	S	C	.	.	H	α-helix	trans	-64.4	-27.9	177.3	-162.1	-114.6	0	0	0	112.7	Y277 S278 A279 L283 S284 I285	Y277-F281 WeakPolarHBondContact O-CB 3.19Å; Y277-F281 PolarHBondContact O-N 3.21Å; S278-F281 WeakPolarHBondContact O-CB 3.34Å; S278-F281 PolarHBondContact O-N 2.88Å; A279-F281 VanDerWaalsContact C-N 3.28Å; A279-F281 PolarHBondContact O-N 2.97Å; F281-L283 VanDerWaalsContact C-N 3.35Å; F281-L283 PolarHBondContact O-N 3.2Å; F281-S284 CarbonylContact O-C 3.59Å; F281-S284 WeakPolarHBondContact O-CA 3.44Å; F281-S284 VanDerWaalsContact O-CB 3.23Å; F281-S284 WeakPolarHBondContact O-CB 3.45Å; F281-S284 PolarHBondContact O-N 3.4Å; F281-I285 HydrophobicContact CD1-CD1 3.64Å; F281-I285 HydrophobicContact CD1-CG1 3.89Å; F281-I285 HydrophobicContact CE1-CD1 3.72Å; F281-I285 HydrophobicContact CE1-CG1 3.77Å; F281-I285 HydrophobicContact CZ-CG1 4.42Å; F281-I285 WeakPolarHBondContact O-CG1 3.42Å; F281-I285 PolarHBondContact O-N 3.45Å
282	L	94.6	Very high	92.4	Very high	0 Å²	0	43.3 Å²	43.3	0%	0	23%	0.225	C	C	.	.	H	α-helix	trans	-59.4	-41.7	174	-66.6	172.2	0	0	0	112.8	L265 A269 S278 A279 A280 S284 I285 L286 Y334 L337 V338 A341	L265-L282 HydrophobicContact CD2-CB 4.34Å; A269-L282 HydrophobicContact CB-CD1 3.61Å; S278-L282 PolarHBondContact O-N 3.37Å; A279-L282 WeakPolarHBondContact O-CB 3.46Å; A279-L282 PolarHBondContact O-N 3.26Å; A280-L282 VanDerWaalsContact C-N 3.26Å; A280-L282 PolarHBondContact O-N 3.4Å; L282-S284 PolarHBondContact O-N 2.89Å; L282-I285 PolarHBondContact O-N 2.99Å; L282-L286 WeakPolarHBondContact O-CB 3.29Å; L282-L286 PolarHBondContact O-N 3.43Å; L282-Y334 HydrophobicContact CD2-CE2 4.04Å; L282-Y334 HydrophobicContact CG-CE2 4.26Å; L282-L337 HydrophobicContact CD1-CB 4.05Å; L282-L337 HydrophobicContact CD1-CD1 4.24Å; L282-L337 HydrophobicContact CD2-CB 4.06Å; L282-V338 HydrophobicContact CD2-CB 4.49Å; L282-V338 HydrophobicContact CD2-CG2 3.81Å; L282-A341 HydrophobicContact CD2-CB 4.31Å
283	L	93.5	Very high	92.6	Very high	0 Å²	0	40.4 Å²	40.4	0%	0	21%	0.21	C	C	.	.	H	α-helix	trans	-63.3	-31.2	173.5	-72.2	177.9	0	0	0	111.5	V42 A162 I262 L265 T266 A280 F281 A287	V42-L283 HydrophobicContact CG2-CD1 4.19Å; A162-L283 HydrophobicContact CB-CB 4.03Å; A162-L283 HydrophobicContact CB-CD1 4.41Å; I262-L283 HydrophobicContact CG1-CD2 4.04Å; L265-L283 HydrophobicContact CB-CD2 4.5Å; L265-L283 HydrophobicContact CD2-CD2 4.16Å; T266-L283 HydrophobicContact CG2-CD1 3.37Å; T266-L283 HydrophobicContact CG2-CG 3.67Å; A280-L283 PolarHBondContact O-N 3.49Å; F281-L283 VanDerWaalsContact C-N 3.35Å; F281-L283 PolarHBondContact O-N 3.2Å; L283-A287 VanDerWaalsContact O-CB 3.26Å; L283-A287 WeakPolarHBondContact O-CB 3.33Å; L283-A287 PolarHBondContact O-N 2.93Å
284	S	94.8	Very high	92.6	Very high	8 Å²	8	38.7 Å²	38.7	6%	0.056	18%	0.183	C	C	.	.	H	α-helix	trans	-72.7	-43.1	179.1	-48.4	0	0	0	0	112.1	S159 P163 A280 F281 L282 A287 F288	S159-S284 PolarHBondContact O-OG 3.41Å; P163-S284 WeakPolarHBondContact CD-OG 3.32Å; A280-S284 PolarHBondContact O-OG 3.33Å; F281-S284 CarbonylContact O-C 3.59Å; F281-S284 WeakPolarHBondContact O-CA 3.44Å; F281-S284 VanDerWaalsContact O-CB 3.23Å; F281-S284 WeakPolarHBondContact O-CB 3.45Å; F281-S284 PolarHBondContact O-N 3.4Å; L282-S284 PolarHBondContact O-N 2.89Å; S284-A287 PolarHBondContact O-N 3.48Å; S284-F288 WeakPolarHBondContact O-CB 3.41Å; S284-F288 PolarHBondContact O-N 3.39Å
285	I	95.3	Very high	92.5	Very high	28 Å²	28	41 Å²	41	14%	0.144	20%	0.198	C	C	.	.	H	α-helix	trans	-60.9	-48	173.8	-64.9	171.8	0	0	0	109.9	F281 L282 A287 F288 V289 V338 A341 V342	F281-I285 HydrophobicContact CD1-CD1 3.64Å; F281-I285 HydrophobicContact CD1-CG1 3.89Å; F281-I285 HydrophobicContact CE1-CD1 3.72Å; F281-I285 HydrophobicContact CE1-CG1 3.77Å; F281-I285 HydrophobicContact CZ-CG1 4.42Å; F281-I285 WeakPolarHBondContact O-CG1 3.42Å; F281-I285 PolarHBondContact O-N 3.45Å; L282-I285 PolarHBondContact O-N 2.99Å; I285-A287 VanDerWaalsContact C-N 3.33Å; I285-A287 PolarHBondContact O-N 2.86Å; I285-F288 PolarHBondContact O-N 3.42Å; I285-V289 WeakPolarHBondContact O-CG2 3.38Å; I285-V289 PolarHBondContact O-N 2.95Å; I285-V338 HydrophobicContact CD1-CB 4.45Å; I285-V338 HydrophobicContact CD1-CG1 3.92Å; I285-V338 HydrophobicContact CD1-CG2 3.97Å; I285-A341 HydrophobicContact CG2-CB 4.28Å; I285-V342 HydrophobicContact CG2-CG2 3.78Å
286	L	95.1	Very high	92.4	Very high	1 Å²	1	39.2 Å²	39.2	1%	0.005	19%	0.193	C	C	.	.	H	α-helix	trans	-55.3	-49.5	176.6	-177	163.9	0	0	0	111.2	I262 L265 L282 V289 D290 A341 F344	I262-L286 HydrophobicContact CD1-CD1 4.2Å; I262-L286 HydrophobicContact CD1-CD2 4.08Å; I262-L286 HydrophobicContact CG1-CD1 4.4Å; L265-L286 HydrophobicContact CD2-CD1 4.12Å; L282-L286 WeakPolarHBondContact O-CB 3.29Å; L282-L286 PolarHBondContact O-N 3.43Å; L286-V289 PolarHBondContact O-N 3.36Å; L286-D290 WeakPolarHBondContact O-CB 3.33Å; L286-D290 PolarHBondContact O-N 3.5Å; L286-A341 HydrophobicContact CB-CB 4.46Å; L286-F344 HydrophobicContact CD1-CD1 3.27Å; L286-F344 HydrophobicContact CD1-CE1 3.47Å; L286-F344 VanDerWaalsContact CD1-CE1 3.47Å; L286-F344 HydrophobicContact CD1-CG 4.1Å; L286-F344 HydrophobicContact CD1-CZ 4.41Å; L286-F344 HydrophobicContact CG-CD1 4.34Å
287	A	94.6	Very high	92.4	Very high	0 Å²	0	37.2 Å²	37.2	0%	0	18%	0.184	C	C	.	.	H	α-helix	trans	-65.6	-40.3	-179.5	0	0	0	0	0	112.3	P155 L158 L283 S284 I285 V289 D290 M291	P155-A287 HydrophobicContact CB-CB 4.33Å; P155-A287 WeakPolarHBondContact CB-O 3.39Å; P155-A287 WeakPolarHBondContact O-CB 3.48Å; L158-A287 HydrophobicContact CB-CB 3.87Å; L158-A287 HydrophobicContact CD2-CB 3.91Å; L158-A287 HydrophobicContact CG-CB 3.85Å; L283-A287 VanDerWaalsContact O-CB 3.26Å; L283-A287 WeakPolarHBondContact O-CB 3.33Å; L283-A287 PolarHBondContact O-N 2.93Å; S284-A287 PolarHBondContact O-N 3.48Å; I285-A287 VanDerWaalsContact C-N 3.33Å; I285-A287 PolarHBondContact O-N 2.86Å; A287-V289 VanDerWaalsContact C-N 3.33Å; A287-V289 PolarHBondContact O-N 2.99Å; A287-D290 PolarHBondContact O-N 3.49Å; A287-M291 PolarHBondContact O-N 3.02Å
288	F	94.6	Very high	92.2	Very high	116 Å²	116	32.7 Å²	32.7	51%	0.509	17%	0.169	S	C	.	.	H	α-helix	trans	-61.1	-42.9	175.7	-173.6	-99.5	0	0	0	111.4	S284 I285 M291 F292	S284-F288 WeakPolarHBondContact O-CB 3.41Å; S284-F288 PolarHBondContact O-N 3.39Å; I285-F288 PolarHBondContact O-N 3.42Å; F288-M291 VanDerWaalsContact O-CB 3.26Å; F288-M291 WeakPolarHBondContact O-CB 3.49Å; F288-M291 PolarHBondContact O-N 3.4Å; F288-F292 HydrophobicContact CD1-CD2 4.44Å; F288-F292 HydrophobicContact CD1-CE2 4.13Å; F288-F292 HydrophobicContact CD2-CE2 4.22Å; F288-F292 HydrophobicContact CE1-CD2 4.24Å; F288-F292 AromaticContact CE1-CE2 3.65Å; F288-F292 HydrophobicContact CE1-CE2 3.65Å; F288-F292 AromaticContact CE2-CE2 3.75Å; F288-F292 HydrophobicContact CE2-CE2 3.75Å; F288-F292 HydrophobicContact CE2-CZ 4.37Å; F288-F292 HydrophobicContact CG-CE2 4.41Å; F288-F292 HydrophobicContact CZ-CD2 4.45Å; F288-F292 AromaticContact CZ-CE2 3.46Å; F288-F292 HydrophobicContact CZ-CE2 3.46Å; F288-F292 VanDerWaalsContact CZ-CE2 3.46Å; F288-F292 HydrophobicContact CZ-CZ 4.09Å; F288-F292 VanDerWaalsContact O-CD2 3.24Å; F288-F292 WeakPolarHBondContact O-CD2 3.23Å
289	V	95.8	Very high	92	Very high	28 Å²	28	37.7 Å²	37.7	17%	0.17	19%	0.192	C	C	.	.	H	α-helix	trans	-67.9	-42.6	176.4	178.5	0	0	0	0	111.6	I285 L286 A287 M291 F292 A293 V342 F346	I285-V289 WeakPolarHBondContact O-CG2 3.38Å; I285-V289 PolarHBondContact O-N 2.95Å; L286-V289 PolarHBondContact O-N 3.36Å; A287-V289 VanDerWaalsContact C-N 3.33Å; A287-V289 PolarHBondContact O-N 2.99Å; V289-M291 PolarHBondContact O-N 2.99Å; V289-F292 PolarHBondContact O-N 3.48Å; V289-F292 VanDerWaalsContact O-N 3.14Å; V289-A293 VanDerWaalsContact O-CB 3.29Å; V289-A293 WeakPolarHBondContact O-CB 3.15Å; V289-A293 PolarHBondContact O-N 3.35Å; V289-V342 HydrophobicContact CG1-CG1 4.48Å; V289-V342 WeakPolarHBondContact CG1-O 3.46Å; V289-V342 HydrophobicContact CG2-CB 4.35Å; V289-V342 HydrophobicContact CG2-CG1 4.15Å; V289-V342 HydrophobicContact CG2-CG2 4.16Å; V289-F346 HydrophobicContact CG1-CB 3.95Å
290	D	93	Very high	91.9	Very high	2 Å²	2	41 Å²	41	1%	0.011	21%	0.21	C	C	.	.	H	α-helix	trans	-56	-38.8	174.2	177	20.2	0	0	0	111.6	P155 L286 A287 F292 A293 R294 G349	P155-D290 HydrophobicContact CB-CB 4.42Å; L286-D290 WeakPolarHBondContact O-CB 3.33Å; L286-D290 PolarHBondContact O-N 3.5Å; A287-D290 PolarHBondContact O-N 3.49Å; D290-F292 VanDerWaalsContact C-N 3.26Å; D290-F292 PolarHBondContact O-N 3.42Å; D290-A293 PolarHBondContact O-N 3.31Å; D290-R294 VanDerWaalsContact CG-NH2 3.33Å; D290-R294 VanDerWaalsContact O-CB 3.31Å; D290-R294 WeakPolarHBondContact O-CB 3.17Å; D290-R294 PolarHBondContact O-N 3.49Å; D290-R294 IonicContact OD1-CZ 2.74Å; D290-R294 IonicContact OD1-NE 3.69Å; D290-R294 PolarHBondContact OD1-NE 2.79Å; D290-R294 VanDerWaalsContact OD1-NE 3.08Å; D290-R294 IonicContact OD1-NH2 3.78Å; D290-R294 PolarHBondContact OD1-NH2 3.24Å; D290-R294 VanDerWaalsContact OD1-NH2 3.08Å; D290-R294 IonicContact OD2-CZ 2.76Å; D290-R294 IonicContact OD2-NH2 3.48Å; D290-R294 PolarHBondContact OD2-NH2 3.26Å; D290-G349 WeakPolarHBondContact OD1-CA 3.34Å
291	M	90.8	Very high	91.6	Very high	62 Å²	62	41 Å²	41	31%	0.305	21%	0.209	S	C	.	.	H	α-helix	trans	-54.4	-39.5	177.1	-168.7	-178.2	173.6	0	0	113	P155 V156 A287 F288 V289 P295	P155-M291 HydrophobicContact CB-CB 3.97Å; P155-M291 HydrophobicContact CG-CB 3.98Å; P155-M291 HydrophobicContact CG-CG 4.28Å; V156-M291 HydrophobicContact CG2-CE 3.46Å; V156-M291 VanDerWaalsContact CG2-CE 3.46Å; V156-M291 HydrophobicContact CG2-CG 4.3Å; V156-M291 HydrophobicContact CG2-SD 3.5Å; V156-M291 VanDerWaalsContact CG2-SD 3.5Å; A287-M291 PolarHBondContact O-N 3.02Å; F288-M291 VanDerWaalsContact O-CB 3.26Å; F288-M291 WeakPolarHBondContact O-CB 3.49Å; F288-M291 PolarHBondContact O-N 3.4Å; V289-M291 PolarHBondContact O-N 2.99Å; M291-P295 WeakPolarHBondContact O-CD 3.4Å; M291-P295 WeakPolarHBondContact O-CG 3.44Å
292	F	91.5	Very high	91.1	Very high	124 Å²	124	39.1 Å²	39.1	54%	0.544	21%	0.205	S	C	.	.	H	α-helix	trans	-91.6	-32.8	178.1	-64.1	-80.1	0	0	0	112.8	F288 V289 D290 S296	F288-F292 HydrophobicContact CD1-CD2 4.44Å; F288-F292 HydrophobicContact CD1-CE2 4.13Å; F288-F292 HydrophobicContact CD2-CE2 4.22Å; F288-F292 HydrophobicContact CE1-CD2 4.24Å; F288-F292 AromaticContact CE1-CE2 3.65Å; F288-F292 HydrophobicContact CE1-CE2 3.65Å; F288-F292 AromaticContact CE2-CE2 3.75Å; F288-F292 HydrophobicContact CE2-CE2 3.75Å; F288-F292 HydrophobicContact CE2-CZ 4.37Å; F288-F292 HydrophobicContact CG-CE2 4.41Å; F288-F292 HydrophobicContact CZ-CD2 4.45Å; F288-F292 AromaticContact CZ-CE2 3.46Å; F288-F292 HydrophobicContact CZ-CE2 3.46Å; F288-F292 VanDerWaalsContact CZ-CE2 3.46Å; F288-F292 HydrophobicContact CZ-CZ 4.09Å; F288-F292 VanDerWaalsContact O-CD2 3.24Å; F288-F292 WeakPolarHBondContact O-CD2 3.23Å; V289-F292 PolarHBondContact O-N 3.48Å; V289-F292 VanDerWaalsContact O-N 3.14Å; D290-F292 VanDerWaalsContact C-N 3.26Å; D290-F292 PolarHBondContact O-N 3.42Å; F292-S296 WeakPolarHBondContact O-CB 3.21Å; F292-S296 PolarHBondContact O-N 2.91Å; F292-S296 PolarHBondContact O-OG 2.89Å
293	A	92.1	Very high	90.7	Very high	2 Å²	2	41.5 Å²	41.5	2%	0.017	22%	0.221	C	C	.	.	H	α-helix	trans	-64.8	-40.3	180	0	0	0	0	0	111.7	V289 D290 S296 M297 F346	V289-A293 VanDerWaalsContact O-CB 3.29Å; V289-A293 WeakPolarHBondContact O-CB 3.15Å; V289-A293 PolarHBondContact O-N 3.35Å; D290-A293 PolarHBondContact O-N 3.31Å; A293-S296 WeakPolarHBondContact CA-OG 3.14Å; A293-S296 PolarHBondContact O-N 3.32Å; A293-S296 PolarHBondContact O-OG 3.37Å; A293-M297 VanDerWaalsContact O-CB 3.27Å; A293-M297 WeakPolarHBondContact O-CB 3.41Å; A293-M297 VanDerWaalsContact O-CG 3.26Å; A293-M297 WeakPolarHBondContact O-CG 3.42Å; A293-M297 PolarHBondContact O-N 3.02Å; A293-F346 HydrophobicContact CB-CB 4.47Å; A293-F346 HydrophobicContact CB-CD2 3.58Å; A293-F346 HydrophobicContact CB-CE2 4.16Å; A293-F346 HydrophobicContact CB-CG 4.29Å
294	R	88.6	Confident	90.2	Very high	30 Å²	30	50.5 Å²	50.5	11%	0.113	26%	0.26	C	S	.	.	H	α-helix	trans	-67.5	-48.5	-173.5	-173.7	-175.9	-59.7	-163.9	-3.6	113.3	M151 D290 G298 S353	M151-R294 PolarHBondContact O-NH1 2.9Å; D290-R294 VanDerWaalsContact CG-NH2 3.33Å; D290-R294 VanDerWaalsContact O-CB 3.31Å; D290-R294 WeakPolarHBondContact O-CB 3.17Å; D290-R294 PolarHBondContact O-N 3.49Å; D290-R294 IonicContact OD1-CZ 2.74Å; D290-R294 IonicContact OD1-NE 3.69Å; D290-R294 PolarHBondContact OD1-NE 2.79Å; D290-R294 VanDerWaalsContact OD1-NE 3.08Å; D290-R294 IonicContact OD1-NH2 3.78Å; D290-R294 PolarHBondContact OD1-NH2 3.24Å; D290-R294 VanDerWaalsContact OD1-NH2 3.08Å; D290-R294 IonicContact OD2-CZ 2.76Å; D290-R294 IonicContact OD2-NH2 3.48Å; D290-R294 PolarHBondContact OD2-NH2 3.26Å; R294-G298 PolarHBondContact O-N 3.1Å; R294-S353 WeakPolarHBondContact O-CB 3.43Å
295	P	88.3	Confident	89.7	Confident	69 Å²	69	61 Å²	61	45%	0.448	30%	0.299	S	S	.	.	H	α-helix	trans	-66.1	-40.8	173.4	-21.4	34	0	0	0	112.8	M291 G298 L299	M291-P295 WeakPolarHBondContact O-CD 3.4Å; M291-P295 WeakPolarHBondContact O-CG 3.44Å; P295-G298 PolarHBondContact O-N 2.9Å; P295-L299 VanDerWaalsContact O-CG 3.3Å; P295-L299 WeakPolarHBondContact O-CG 3.49Å; P295-L299 PolarHBondContact O-N 2.91Å
296	S	90.1	Very high	89.3	Confident	50 Å²	50	61.4 Å²	61.4	35%	0.35	30%	0.301	S	S	.	.	H	α-helix	trans	-65.1	-44.9	-178.2	55.9	0	0	0	0	112.2	F292 A293 L299 L300	F292-S296 WeakPolarHBondContact O-CB 3.21Å; F292-S296 PolarHBondContact O-N 2.91Å; F292-S296 PolarHBondContact O-OG 2.89Å; A293-S296 WeakPolarHBondContact CA-OG 3.14Å; A293-S296 PolarHBondContact O-N 3.32Å; A293-S296 PolarHBondContact O-OG 3.37Å; S296-L299 PolarHBondContact O-N 3.3Å; S296-L300 WeakPolarHBondContact O-CB 3.34Å; S296-L300 PolarHBondContact O-N 2.94Å
297	M	90.3	Very high	88.8	Confident	22 Å²	22	65.8 Å²	65.8	11%	0.108	32%	0.318	C	S	.	.	H	α-helix	trans	-73	-31.6	177.8	-64.9	-58.1	106	0	0	112.7	A293 L300 A301 F313 F346 M350	A293-M297 VanDerWaalsContact O-CB 3.27Å; A293-M297 WeakPolarHBondContact O-CB 3.41Å; A293-M297 VanDerWaalsContact O-CG 3.26Å; A293-M297 WeakPolarHBondContact O-CG 3.42Å; A293-M297 PolarHBondContact O-N 3.02Å; M297-L300 HydrophobicContact CE-CD2 3.98Å; M297-L300 PolarHBondContact O-N 3.25Å; M297-L300 HydrophobicContact SD-CD2 3.84Å; M297-A301 WeakPolarHBondContact O-CB 3.44Å; M297-A301 PolarHBondContact O-N 3.35Å; M297-F313 HydrophobicContact SD-CZ 4.31Å; M297-F346 HydrophobicContact CE-CE2 3.96Å; M297-F346 HydrophobicContact CE-CZ 3.68Å; M297-F346 HydrophobicContact CG-CE2 4.35Å; M297-F346 HydrophobicContact CG-CZ 4.18Å; M297-F346 HydrophobicContact SD-CE1 4.48Å; M297-F346 HydrophobicContact SD-CE2 4.36Å; M297-F346 HydrophobicContact SD-CZ 3.74Å; M297-M350 HydrophobicContact CB-CB 4.33Å; M297-M350 HydrophobicContact CB-CG 4.13Å; M297-M350 HydrophobicContact CG-CB 3.96Å; M297-M350 HydrophobicContact CG-CE 4.08Å; M297-M350 HydrophobicContact CG-CG 3.92Å; M297-M350 HydrophobicContact SD-CE 3.55Å; M297-M350 VanDerWaalsContact SD-CE 3.55Å; M297-M350 HydrophobicContact SD-CG 4.36Å
298	G	85.8	Confident	88.3	Confident	9 Å²	9	70 Å²	70	9%	0.093	35%	0.345	C	S	.	.	H	α-helix	trans	-64.5	-43.3	170.6	0	0	0	0	0	112.5	R294 P295 L300 A301 N302	R294-G298 PolarHBondContact O-N 3.1Å; P295-G298 PolarHBondContact O-N 2.9Å; G298-L300 VanDerWaalsContact C-N 3.31Å; G298-L300 PolarHBondContact O-N 3.47Å; G298-A301 PolarHBondContact O-N 3.46Å; G298-N302 PolarHBondContact O-N 3.23Å; G298-N302 PolarHBondContact O-ND2 3.13Å
299	L	86.3	Confident	88	Confident	132 Å²	132	72.7 Å²	72.7	69%	0.691	35%	0.351	S	S	*	.	H	α-helix	trans	-63.2	-39.9	173.4	-71.2	172.7	0	0	0	111.6	P295 S296 N302 S303	P295-L299 VanDerWaalsContact O-CG 3.3Å; P295-L299 WeakPolarHBondContact O-CG 3.49Å; P295-L299 PolarHBondContact O-N 2.91Å; S296-L299 PolarHBondContact O-N 3.3Å; L299-N302 PolarHBondContact O-N 3.08Å; L299-S303 PolarHBondContact O-N 3.44Å
300	L	89.1	Confident	87.6	Confident	70 Å²	70	71.3 Å²	71.3	37%	0.366	34%	0.343	S	S	.	.	H	α-helix	trans	-63.2	-44	176.6	-175.7	60.5	0	0	0	111.8	S296 M297 G298 N302 S303 I306 F313	S296-L300 WeakPolarHBondContact O-CB 3.34Å; S296-L300 PolarHBondContact O-N 2.94Å; M297-L300 HydrophobicContact CE-CD2 3.98Å; M297-L300 PolarHBondContact O-N 3.25Å; M297-L300 HydrophobicContact SD-CD2 3.84Å; G298-L300 VanDerWaalsContact C-N 3.31Å; G298-L300 PolarHBondContact O-N 3.47Å; L300-N302 PolarHBondContact O-N 2.95Å; L300-S303 WeakPolarHBondContact O-CB 3.26Å; L300-S303 PolarHBondContact O-N 2.78Å; L300-I306 HydrophobicContact CD1-CD1 3.48Å; L300-I306 VanDerWaalsContact CD1-CD1 3.48Å; L300-I306 HydrophobicContact CD2-CD1 4.23Å; L300-I306 HydrophobicContact CG-CD1 3.47Å; L300-I306 VanDerWaalsContact CG-CD1 3.47Å; L300-I306 WeakPolarHBondContact O-CD1 3.33Å; L300-F313 HydrophobicContact CD2-CE2 4.41Å; L300-F313 HydrophobicContact CD2-CZ 4.14Å
301	A	85.9	Confident	87.4	Confident	0 Å²	0	71.9 Å²	71.9	0%	0	35%	0.346	C	S	.	.	H	α-helix	trans	-61.7	-28.6	176.5	0	0	0	0	0	113	M297 G298 S303 R307 I310 F313 V354 E357	M297-A301 WeakPolarHBondContact O-CB 3.44Å; M297-A301 PolarHBondContact O-N 3.35Å; G298-A301 PolarHBondContact O-N 3.46Å; A301-S303 VanDerWaalsContact C-N 3.34Å; A301-R307 WeakPolarHBondContact O-CA 3.38Å; A301-R307 PolarHBondContact O-N 3.26Å; A301-I310 HydrophobicContact CB-CD1 4.19Å; A301-I310 HydrophobicContact CB-CG1 4.49Å; A301-F313 HydrophobicContact CB-CD1 4.19Å; A301-F313 HydrophobicContact CB-CE1 4.09Å; A301-V354 HydrophobicContact CB-CG2 4.23Å; A301-E357 VanDerWaalsContact CB-OE2 3.24Å; A301-E357 WeakPolarHBondContact CB-OE2 3.36Å
302	N	83.8	Confident	87.5	Confident	69 Å²	69	71.6 Å²	71.6	37%	0.369	34%	0.342	S	S	.	.	T	Hydrogen-bonded Turn	trans	-82.3	-5.5	175.9	-75.3	-60.7	0	0	0	114.6	G298 L299 L300 R307 E357	G298-N302 PolarHBondContact O-N 3.23Å; G298-N302 PolarHBondContact O-ND2 3.13Å; L299-N302 PolarHBondContact O-N 3.08Å; L300-N302 PolarHBondContact O-N 2.95Å; N302-R307 PolarHBondContact OD1-NH1 3.46Å; N302-E357 PolarHBondContact ND2-OE1 2.9Å
303	S	86.1	Confident	87.6	Confident	50 Å²	50	67 Å²	67	35%	0.35	32%	0.322	S	S	.	.	S	Bend	trans	-65.1	147.7	176.3	-177.9	0	0	0	0	111.9	L299 L300 A301 W305 I306 R307	L299-S303 PolarHBondContact O-N 3.44Å; L300-S303 WeakPolarHBondContact O-CB 3.26Å; L300-S303 PolarHBondContact O-N 2.78Å; A301-S303 VanDerWaalsContact C-N 3.34Å; S303-W305 PolarHBondContact O-N 3.01Å; S303-I306 PolarHBondContact O-N 3.48Å; S303-I306 VanDerWaalsContact O-N 3.08Å; S303-R307 WeakPolarHBondContact O-CB 3.36Å; S303-R307 PolarHBondContact O-N 3.36Å
304	K	82.4	Confident	87.6	Confident	189 Å²	189	67 Å²	67	82%	0.822	32%	0.321	S	S	*	.	T	Hydrogen-bonded Turn	trans	-54.3	-25.5	-179.1	-67.3	-175.9	179.6	-179	0	113.5	P308	K304-P308 VanDerWaalsContact O-CD 3.26Å; K304-P308 WeakPolarHBondContact O-CD 3.35Å
305	W	83.8	Confident	87.9	Confident	228 Å²	228	65.6 Å²	65.6	86%	0.864	32%	0.316	S	S	*	.	T	Hydrogen-bonded Turn	trans	-85.8	-32.5	-176	-60.9	10.6	0	0	0	112.3	S303	S303-W305 PolarHBondContact O-N 3.01Å
306	I	87.5	Confident	88.3	Confident	37 Å²	37	67.8 Å²	67.8	19%	0.19	32%	0.319	C	S	.	.	T	Hydrogen-bonded Turn	trans	-99	-34.4	-172.7	-63.2	170.6	0	0	0	110.7	L300 S303 P308 R309 I310 F313	L300-I306 HydrophobicContact CD1-CD1 3.48Å; L300-I306 VanDerWaalsContact CD1-CD1 3.48Å; L300-I306 HydrophobicContact CD2-CD1 4.23Å; L300-I306 HydrophobicContact CG-CD1 3.47Å; L300-I306 VanDerWaalsContact CG-CD1 3.47Å; L300-I306 WeakPolarHBondContact O-CD1 3.33Å; S303-I306 PolarHBondContact O-N 3.48Å; S303-I306 VanDerWaalsContact O-N 3.08Å; I306-P308 VanDerWaalsContact C-CD 3.49Å; I306-R309 CarbonylContact O-C 3.43Å; I306-R309 WeakPolarHBondContact O-CA 3.39Å; I306-R309 PolarHBondContact O-N 3.42Å; I306-I310 PolarHBondContact O-N 2.87Å; I306-F313 HydrophobicContact CG2-CB 3.81Å; I306-F313 HydrophobicContact CG2-CD1 4Å; I306-F313 HydrophobicContact CG2-CD2 4.21Å; I306-F313 HydrophobicContact CG2-CG 3.75Å
307	R	84.6	Confident	88.5	Confident	93 Å²	93	65.4 Å²	65.4	35%	0.351	30%	0.302	S	S	.	.	G	3₁₀ helix	trans	-51	-45.8	-179.1	-169.8	76.4	-171.1	-132.4	-0.1	113.4	A301 N302 S303 R309 I310	A301-R307 WeakPolarHBondContact O-CA 3.38Å; A301-R307 PolarHBondContact O-N 3.26Å; N302-R307 PolarHBondContact OD1-NH1 3.46Å; S303-R307 WeakPolarHBondContact O-CB 3.36Å; S303-R307 PolarHBondContact O-N 3.36Å; R307-R309 PolarHBondContact O-N 2.96Å; R307-R309 VanDerWaalsContact O-N 3.15Å; R307-I310 PolarHBondContact O-N 3.22Å
308	P	84.6	Confident	88.8	Confident	88 Å²	88	64.4 Å²	64.4	57%	0.571	30%	0.297	S	S	*	.	G	3₁₀ helix	trans	-67.9	-13.1	178.6	-19.1	33.6	0	0	0	114.4	K304 I306	K304-P308 VanDerWaalsContact O-CD 3.26Å; K304-P308 WeakPolarHBondContact O-CD 3.35Å; I306-P308 VanDerWaalsContact C-CD 3.49Å
309	R	87.9	Confident	89.3	Confident	172 Å²	172	67 Å²	67	65%	0.649	31%	0.309	S	S	*	.	G	3₁₀ helix	trans	-129	26.5	-176	-66.8	-172.7	-177.4	178.9	2.4	111.8	I306 R307 Q311 Y312 F313	I306-R309 CarbonylContact O-C 3.43Å; I306-R309 WeakPolarHBondContact O-CA 3.39Å; I306-R309 PolarHBondContact O-N 3.42Å; R307-R309 PolarHBondContact O-N 2.96Å; R307-R309 VanDerWaalsContact O-N 3.15Å; R309-Q311 PolarHBondContact O-N 3.46Å; R309-Q311 VanDerWaalsContact O-N 3.14Å; R309-Y312 HydrophobicContact CB-CD2 4.08Å; R309-Y312 HydrophobicContact CG-CD2 4.39Å; R309-Y312 PolarHBondContact O-N 3.21Å; R309-F313 PolarHBondContact O-N 3Å
310	I	88.2	Confident	89.8	Confident	0 Å²	0	63.4 Å²	63.4	0%	0	29%	0.286	C	S	.	.	H	α-helix	trans	-58.9	-31.8	-173.1	-167.2	171.5	0	0	0	112.7	A301 I306 R307 Y312 F313 F314 V354 E357 T358 D361	A301-I310 HydrophobicContact CB-CD1 4.19Å; A301-I310 HydrophobicContact CB-CG1 4.49Å; I306-I310 PolarHBondContact O-N 2.87Å; R307-I310 PolarHBondContact O-N 3.22Å; I310-Y312 VanDerWaalsContact C-N 3.35Å; I310-Y312 PolarHBondContact O-N 3.16Å; I310-F313 WeakPolarHBondContact O-CB 3.36Å; I310-F313 PolarHBondContact O-N 3.02Å; I310-F314 PolarHBondContact O-N 3.23Å; I310-V354 HydrophobicContact CG1-CG1 4.05Å; I310-E357 HydrophobicContact CD1-CB 3.72Å; I310-T358 HydrophobicContact CB-CG2 4.47Å; I310-T358 HydrophobicContact CD1-CG2 4.46Å; I310-T358 HydrophobicContact CG1-CG2 3.91Å; I310-T358 HydrophobicContact CG2-CG2 4.18Å; I310-D361 HydrophobicContact CG2-CB 4.17Å
311	Q	88.7	Confident	90.2	Very high	14 Å²	14	60 Å²	60	7%	0.065	27%	0.269	C	S	.	.	H	α-helix	trans	-62.1	-37.6	175.3	-68.5	176.9	15.6	0	0	113.3	R309 F314 S315 N422 Y426	R309-Q311 PolarHBondContact O-N 3.46Å; R309-Q311 VanDerWaalsContact O-N 3.14Å; Q311-F314 PolarHBondContact O-N 2.83Å; Q311-S315 PolarHBondContact O-N 3.45Å; Q311-S315 VanDerWaalsContact O-N 3.15Å; Q311-S315 PolarHBondContact O-OG 2.87Å; Q311-N422 HydrophobicContact CB-CB 4.38Å; Q311-N422 PolarHBondContact O-ND2 3.14Å; Q311-N422 PolarHBondContact OE1-OD1 2.64Å; Q311-Y426 HydrophobicContact CB-CE2 4.22Å
312	Y	91.6	Very high	90.6	Very high	56 Å²	56	60 Å²	60	22%	0.22	27%	0.269	C	S	.	.	H	α-helix	trans	-73.3	-35.9	174.9	-66.7	-68.7	0	0	0	111.6	R309 I310 F314 S315 F316 F419 N422 F423 Y426	R309-Y312 HydrophobicContact CB-CD2 4.08Å; R309-Y312 HydrophobicContact CG-CD2 4.39Å; R309-Y312 PolarHBondContact O-N 3.21Å; I310-Y312 VanDerWaalsContact C-N 3.35Å; I310-Y312 PolarHBondContact O-N 3.16Å; Y312-F314 VanDerWaalsContact C-N 3.28Å; Y312-F314 PolarHBondContact O-N 3.21Å; Y312-S315 PolarHBondContact O-N 2.87Å; Y312-F316 PolarHBondContact O-N 3.48Å; Y312-F419 AromaticContact CD1-CD2 3.86Å; Y312-F419 HydrophobicContact CD1-CD2 3.86Å; Y312-F419 AromaticContact CD1-CE2 3.62Å; Y312-F419 HydrophobicContact CD1-CE2 3.62Å; Y312-F419 HydrophobicContact CD1-CZ 4.22Å; Y312-F419 HydrophobicContact CE1-CD2 4.45Å; Y312-F419 HydrophobicContact CE1-CE2 4.2Å; Y312-F419 HydrophobicContact CE1-CZ 4.38Å; Y312-N422 HydrophobicContact CE1-CB 4.47Å; Y312-F423 WeakPolarHBondContact OH-CA 3.28Å; Y312-Y426 HydrophobicContact CD2-CD2 4.48Å; Y312-Y426 HydrophobicContact CD2-CE2 4.04Å; Y312-Y426 AromaticContact CE2-CD2 3.48Å; Y312-Y426 HydrophobicContact CE2-CD2 3.48Å; Y312-Y426 VanDerWaalsContact CE2-CD2 3.48Å; Y312-Y426 AromaticContact CE2-CE2 3.44Å; Y312-Y426 HydrophobicContact CE2-CE2 3.44Å; Y312-Y426 VanDerWaalsContact CE2-CE2 3.44Å; Y312-Y426 HydrophobicContact CE2-CG 4.38Å; Y312-Y426 AromaticContact CZ-CD2 3.58Å; Y312-Y426 AromaticContact CZ-CE2 3.93Å; Y312-Y426 VanDerWaalsContact OH-CD2 3.31Å; Y312-Y426 WeakPolarHBondContact OH-CD2 3.34Å
313	F	93.4	Very high	91.2	Very high	28 Å²	28	59.6 Å²	59.6	12%	0.123	27%	0.268	C	S	.	.	H	α-helix	trans	-62.4	-38.4	173.9	-175.6	-115.6	0	0	0	111.5	M297 L300 A301 I306 R309 I310 F316 A317 M350 V354	M297-F313 HydrophobicContact SD-CZ 4.31Å; L300-F313 HydrophobicContact CD2-CE2 4.41Å; L300-F313 HydrophobicContact CD2-CZ 4.14Å; A301-F313 HydrophobicContact CB-CD1 4.19Å; A301-F313 HydrophobicContact CB-CE1 4.09Å; I306-F313 HydrophobicContact CG2-CB 3.81Å; I306-F313 HydrophobicContact CG2-CD1 4Å; I306-F313 HydrophobicContact CG2-CD2 4.21Å; I306-F313 HydrophobicContact CG2-CG 3.75Å; R309-F313 PolarHBondContact O-N 3Å; I310-F313 WeakPolarHBondContact O-CB 3.36Å; I310-F313 PolarHBondContact O-N 3.02Å; F313-F316 PolarHBondContact O-N 3.47Å; F313-A317 PolarHBondContact O-N 3.37Å; F313-M350 HydrophobicContact CE1-CG 4.49Å; F313-M350 HydrophobicContact CZ-CG 4.26Å; F313-M350 HydrophobicContact CZ-SD 4.3Å; F313-V354 HydrophobicContact CD1-CG1 4.22Å; F313-V354 HydrophobicContact CD1-CG2 3.67Å; F313-V354 HydrophobicContact CE1-CG2 3.51Å
314	F	93.6	Very high	91.7	Very high	2 Å²	2	57.7 Å²	57.7	1%	0.009	26%	0.255	C	S	.	.	H	α-helix	trans	-62.6	-48.9	171.9	-177	-117	0	0	0	112.4	Y247 M254 I310 Q311 Y312 F316 A317 V318 V351 V354 L355 T358 L418	Y247-F314 HydrophobicContact CE2-CE1 4.22Å; M254-F314 HydrophobicContact SD-CZ 4.29Å; I310-F314 PolarHBondContact O-N 3.23Å; Q311-F314 PolarHBondContact O-N 2.83Å; Y312-F314 VanDerWaalsContact C-N 3.28Å; Y312-F314 PolarHBondContact O-N 3.21Å; F314-F316 VanDerWaalsContact C-N 3.26Å; F314-F316 PolarHBondContact O-N 2.93Å; F314-A317 WeakPolarHBondContact O-CB 3.28Å; F314-A317 PolarHBondContact O-N 3.44Å; F314-A317 VanDerWaalsContact O-N 3.1Å; F314-V318 HydrophobicContact CD2-CG2 4.47Å; F314-V318 HydrophobicContact CE1-CG2 4.26Å; F314-V318 HydrophobicContact CE2-CG2 4.15Å; F314-V318 HydrophobicContact CZ-CG2 4.02Å; F314-V318 WeakPolarHBondContact O-CG2 3.16Å; F314-V318 PolarHBondContact O-N 2.99Å; F314-V351 HydrophobicContact CE2-CG1 4.13Å; F314-V354 HydrophobicContact CB-CG1 3.69Å; F314-V354 HydrophobicContact CD2-CB 4.12Å; F314-V354 HydrophobicContact CD2-CG1 3.89Å; F314-V354 HydrophobicContact CG-CG1 4.23Å; F314-L355 HydrophobicContact CE2-CB 4.27Å; F314-L355 HydrophobicContact CE2-CD1 3.85Å; F314-L355 HydrophobicContact CZ-CD1 3.62Å; F314-T358 HydrophobicContact CB-CG2 3.7Å; F314-T358 HydrophobicContact CG-CG2 4.16Å; F314-L418 HydrophobicContact CD1-CD1 4.03Å; F314-L418 HydrophobicContact CE1-CD1 3.63Å
315	S	94.6	Very high	92.2	Very high	0 Å²	0	48.7 Å²	48.7	0%	0	22%	0.216	C	C	.	.	H	α-helix	trans	-56.8	-42	175.1	-57.9	0	0	0	0	111.7	Q311 Y312 A317 V318 L319 S415 L418 F419	Q311-S315 PolarHBondContact O-N 3.45Å; Q311-S315 VanDerWaalsContact O-N 3.15Å; Q311-S315 PolarHBondContact O-OG 2.87Å; Y312-S315 PolarHBondContact O-N 2.87Å; S315-A317 PolarHBondContact O-N 3.34Å; S315-V318 PolarHBondContact O-N 3.38Å; S315-L319 PolarHBondContact O-N 2.88Å; S315-S415 PolarHBondContact O-OG 3.38Å; S315-L418 WeakPolarHBondContact OG-CB 3.41Å; S315-F419 PolarHBondContact OG-N 3.08Å
316	F	95.4	Very high	92.7	Very high	115 Å²	115	40.4 Å²	40.4	50%	0.504	19%	0.188	S	C	.	.	H	α-helix	trans	-61.3	-43.2	174.8	174.4	-98.1	0	0	0	112.8	Y312 F313 F314 V318 L319 Y320 M350	Y312-F316 PolarHBondContact O-N 3.48Å; F313-F316 PolarHBondContact O-N 3.47Å; F314-F316 VanDerWaalsContact C-N 3.26Å; F314-F316 PolarHBondContact O-N 2.93Å; F316-V318 VanDerWaalsContact C-N 3.31Å; F316-V318 PolarHBondContact O-N 3.42Å; F316-L319 WeakPolarHBondContact O-CB 3.11Å; F316-L319 PolarHBondContact O-N 3.32Å; F316-Y320 WeakPolarHBondContact O-CB 3.45Å; F316-Y320 PolarHBondContact O-N 2.93Å; F316-M350 HydrophobicContact CD1-SD 4.46Å
317	A	95.4	Very high	92.9	Very high	0 Å²	0	43 Å²	43	0%	0	20%	0.202	C	C	.	.	H	α-helix	trans	-59.9	-42.2	176.6	0	0	0	0	0	112.1	F313 F314 S315 Y320 N321 M350 V351	F313-A317 PolarHBondContact O-N 3.37Å; F314-A317 WeakPolarHBondContact O-CB 3.28Å; F314-A317 PolarHBondContact O-N 3.44Å; F314-A317 VanDerWaalsContact O-N 3.1Å; S315-A317 PolarHBondContact O-N 3.34Å; A317-Y320 PolarHBondContact O-N 3.17Å; A317-N321 WeakPolarHBondContact O-CB 3.13Å; A317-N321 PolarHBondContact O-N 3.29Å; A317-M350 HydrophobicContact CB-CB 4.29Å; A317-M350 HydrophobicContact CB-CG 3.58Å; A317-M350 HydrophobicContact CB-SD 3.43Å; A317-M350 WeakPolarHBondContact CB-SD 3.13Å; A317-V351 HydrophobicContact CB-CG2 3.89Å
318	V	96.2	Very high	93.2	Very high	1 Å²	1	38.6 Å²	38.6	1%	0.006	19%	0.185	C	C	.	.	H	α-helix	trans	-67.5	-41.9	176.8	-178.9	0	0	0	0	110.8	M254 F314 S315 F316 Y320 N321 G322 V351 V411	M254-V318 HydrophobicContact CG-CG1 4Å; M254-V318 HydrophobicContact SD-CB 4.5Å; M254-V318 HydrophobicContact SD-CG1 4.02Å; M254-V318 HydrophobicContact SD-CG2 3.59Å; M254-V318 VanDerWaalsContact SD-CG2 3.59Å; F314-V318 HydrophobicContact CD2-CG2 4.47Å; F314-V318 HydrophobicContact CE1-CG2 4.26Å; F314-V318 HydrophobicContact CE2-CG2 4.15Å; F314-V318 HydrophobicContact CZ-CG2 4.02Å; F314-V318 WeakPolarHBondContact O-CG2 3.16Å; F314-V318 PolarHBondContact O-N 2.99Å; S315-V318 PolarHBondContact O-N 3.38Å; F316-V318 VanDerWaalsContact C-N 3.31Å; F316-V318 PolarHBondContact O-N 3.42Å; V318-Y320 PolarHBondContact O-N 3.43Å; V318-N321 WeakPolarHBondContact O-CB 3.23Å; V318-N321 PolarHBondContact O-N 3.49Å; V318-G322 PolarHBondContact O-N 2.61Å; V318-V351 HydrophobicContact CG2-CG2 4.24Å; V318-V411 HydrophobicContact CG1-CG1 3.71Å; V318-V411 WeakPolarHBondContact O-CG1 3.44Å
319	L	96.8	Very high	93.3	Very high	64 Å²	64	34.5 Å²	34.5	34%	0.335	16%	0.159	S	C	.	.	H	α-helix	trans	-58	-50.1	174.5	-172.2	63.8	0	0	0	111.3	S315 F316 N321 G322 V323 I412 S415	S315-L319 PolarHBondContact O-N 2.88Å; F316-L319 WeakPolarHBondContact O-CB 3.11Å; F316-L319 PolarHBondContact O-N 3.32Å; L319-N321 VanDerWaalsContact C-N 3.29Å; L319-N321 PolarHBondContact O-N 3.36Å; L319-G322 PolarHBondContact O-N 3.13Å; L319-V323 WeakPolarHBondContact O-CG2 3.45Å; L319-V323 PolarHBondContact O-N 3.02Å; L319-I412 HydrophobicContact CD1-CG1 4.28Å; L319-I412 HydrophobicContact CD1-CG2 4.03Å; L319-S415 VanDerWaalsContact CB-OG 3.32Å; L319-S415 WeakPolarHBondContact CB-OG 3.26Å; L319-S415 PolarHBondContact N-OG 3.39Å
320	Y	96.7	Very high	93.3	Very high	55 Å²	55	32.4 Å²	32.4	22%	0.216	16%	0.159	C	C	.	.	H	α-helix	trans	-59.2	-41.8	-179.9	173.9	-107.8	0	0	0	111.4	F316 A317 V318 V323 C324 F343 F346 A347	F316-Y320 WeakPolarHBondContact O-CB 3.45Å; F316-Y320 PolarHBondContact O-N 2.93Å; A317-Y320 PolarHBondContact O-N 3.17Å; V318-Y320 PolarHBondContact O-N 3.43Å; Y320-V323 PolarHBondContact O-N 3.37Å; Y320-C324 PolarHBondContact O-N 2.93Å; Y320-C324 PolarHBondContact O-SG 3.16Å; Y320-F343 WeakPolarHBondContact OH-CD1 3.32Å; Y320-F343 PolarHBondContact OH-O 3.15Å; Y320-F346 AromaticContact CE1-CD1 3.81Å; Y320-F346 HydrophobicContact CE1-CD1 3.81Å; Y320-A347 HydrophobicContact CD1-CB 3.45Å; Y320-A347 VanDerWaalsContact CD1-CB 3.45Å; Y320-A347 HydrophobicContact CE1-CB 3.41Å; Y320-A347 VanDerWaalsContact CE1-CB 3.41Å
321	N	96.2	Very high	93.2	Very high	0 Å²	0	33.8 Å²	33.8	0%	0	17%	0.168	C	C	.	.	H	α-helix	trans	-61.4	-46.9	173.9	-173.1	-91.1	0	0	0	112.6	A317 V318 L319 V323 C324 H325 A347 V351	A317-N321 WeakPolarHBondContact O-CB 3.13Å; A317-N321 PolarHBondContact O-N 3.29Å; V318-N321 WeakPolarHBondContact O-CB 3.23Å; V318-N321 PolarHBondContact O-N 3.49Å; L319-N321 VanDerWaalsContact C-N 3.29Å; L319-N321 PolarHBondContact O-N 3.36Å; N321-V323 PolarHBondContact O-N 3.05Å; N321-C324 WeakPolarHBondContact O-CB 3.26Å; N321-C324 PolarHBondContact O-N 2.96Å; N321-H325 PolarHBondContact O-CD2 3.04Å; N321-H325 PolarHBondContact O-N 2.88Å; N321-H325 VanDerWaalsContact O-N 3.14Å; N321-H325 PolarHBondContact OD1-CD2 2.93Å; N321-H325 PolarHBondContact OD1-NE2 2.92Å; N321-H325 VanDerWaalsContact OD1-NE2 3.11Å; N321-A347 HydrophobicContact CB-CB 3.92Å; N321-V351 HydrophobicContact CB-CG2 4.36Å
322	G	95.9	Very high	92.8	Very high	0 Å²	0	39.6 Å²	39.6	0%	0	20%	0.195	C	C	.	.	H	α-helix	trans	-63.3	-39.3	177.5	0	0	0	0	0	113.4	V318 L319 H325 I326	V318-G322 PolarHBondContact O-N 2.61Å; L319-G322 PolarHBondContact O-N 3.13Å; G322-H325 WeakPolarHBondContact O-CB 3.42Å; G322-H325 PolarHBondContact O-N 3.03Å; G322-I326 PolarHBondContact O-N 3.14Å; G322-I326 VanDerWaalsContact O-N 3.12Å
323	V	96.1	Very high	92.7	Very high	60 Å²	60	40 Å²	40	36%	0.364	21%	0.206	S	C	.	.	H	α-helix	trans	-63.2	-43.6	174.2	172.3	0	0	0	0	110.9	L319 Y320 N321 H325 I326 L327 I412	L319-V323 WeakPolarHBondContact O-CG2 3.45Å; L319-V323 PolarHBondContact O-N 3.02Å; Y320-V323 PolarHBondContact O-N 3.37Å; N321-V323 PolarHBondContact O-N 3.05Å; V323-H325 PolarHBondContact O-N 3.46Å; V323-I326 PolarHBondContact O-N 2.84Å; V323-L327 HydrophobicContact CG1-CD1 3.9Å; V323-L327 HydrophobicContact CG1-CG 4.35Å; V323-L327 WeakPolarHBondContact O-CG 3.38Å; V323-L327 PolarHBondContact O-N 3.19Å; V323-L327 VanDerWaalsContact O-N 3.08Å; V323-I412 HydrophobicContact CG2-CD1 4.15Å
324	C	95.3	Very high	92.6	Very high	9 Å²	9	42.3 Å²	42.3	6%	0.061	21%	0.214	C	C	.	.	H	α-helix	trans	-55.6	-41.7	174.7	-67.1	0	0	0	0	111.4	Y320 N321 L327 C328 Y340	Y320-C324 PolarHBondContact O-N 2.93Å; Y320-C324 PolarHBondContact O-SG 3.16Å; N321-C324 WeakPolarHBondContact O-CB 3.26Å; N321-C324 PolarHBondContact O-N 2.96Å; C324-L327 PolarHBondContact O-N 3.17Å; C324-C328 PolarHBondContact O-N 3.4Å; C324-Y340 HydrophobicContact CB-CE2 4.45Å; C324-Y340 VanDerWaalsContact O-CE2 3.3Å; C324-Y340 WeakPolarHBondContact O-CE2 3.5Å
325	H	94.4	Very high	92.5	Very high	0 Å²	0	47.2 Å²	47.2	0%	0	24%	0.244	C	C	.	.	H	α-helix	trans	-66.2	-38.8	178.2	-68.4	-34.6	0	0	0	113.9	P261 N321 G322 V323 L327 C328 P329 Y340 F344	P261-H325 WeakPolarHBondContact CB-CE1 3.44Å; N321-H325 PolarHBondContact O-CD2 3.04Å; N321-H325 PolarHBondContact O-N 2.88Å; N321-H325 VanDerWaalsContact O-N 3.14Å; N321-H325 PolarHBondContact OD1-CD2 2.93Å; N321-H325 PolarHBondContact OD1-NE2 2.92Å; N321-H325 VanDerWaalsContact OD1-NE2 3.11Å; G322-H325 WeakPolarHBondContact O-CB 3.42Å; G322-H325 PolarHBondContact O-N 3.03Å; V323-H325 PolarHBondContact O-N 3.46Å; H325-L327 VanDerWaalsContact C-N 3.28Å; H325-L327 PolarHBondContact O-N 3.11Å; H325-C328 WeakPolarHBondContact O-CB 3.2Å; H325-C328 PolarHBondContact O-N 3.41Å; H325-P329 WeakPolarHBondContact O-CD 3.46Å; H325-Y340 PolarHBondContact ND1-OH 3.32Å; H325-F344 AromaticContact CE1-CD2 3.54Å; H325-F344 AromaticContact CE1-CE2 3.23Å; H325-F344 WeakPolarHBondContact CE1-CE2 3.35Å; H325-F344 AromaticContact CE1-CZ 3.53Å; H325-F344 AromaticContact NE2-CE2 3.66Å
326	I	94.3	Very high	92.5	Very high	55 Å²	55	48 Å²	48	28%	0.282	25%	0.252	S	S	.	.	H	α-helix	trans	-68	-29.7	175.9	-68.7	-171.4	0	0	0	112	G322 V323 P329 F405 I412	G322-I326 PolarHBondContact O-N 3.14Å; G322-I326 VanDerWaalsContact O-N 3.12Å; V323-I326 PolarHBondContact O-N 2.84Å; I326-P329 WeakPolarHBondContact O-CD 3.44Å; I326-F405 HydrophobicContact CG2-CD1 4.01Å; I326-F405 HydrophobicContact CG2-CE1 3.94Å; I326-F405 WeakPolarHBondContact O-CE1 3.48Å; I326-I412 HydrophobicContact CD1-CD1 3.42Å; I326-I412 VanDerWaalsContact CD1-CD1 3.42Å; I326-I412 HydrophobicContact CG1-CD1 4.3Å
327	L	91.3	Very high	92.3	Very high	91 Å²	91	42.5 Å²	42.5	48%	0.476	23%	0.228	S	C	.	.	H	α-helix	trans	-80	-21.1	178.9	-65.8	174.7	0	0	0	113.3	V323 C324 H325 L330	V323-L327 HydrophobicContact CG1-CD1 3.9Å; V323-L327 HydrophobicContact CG1-CG 4.35Å; V323-L327 WeakPolarHBondContact O-CG 3.38Å; V323-L327 PolarHBondContact O-N 3.19Å; V323-L327 VanDerWaalsContact O-N 3.08Å; C324-L327 PolarHBondContact O-N 3.17Å; H325-L327 VanDerWaalsContact C-N 3.28Å; H325-L327 PolarHBondContact O-N 3.11Å; L327-L330 HydrophobicContact CD2-CD1 3.95Å; L327-L330 WeakPolarHBondContact O-CB 3.37Å; L327-L330 PolarHBondContact O-N 2.86Å
328	C	90.5	Very high	92.3	Very high	0 Å²	0	44.2 Å²	44.2	0%	0	24%	0.239	C	C	.	.	G	3₁₀ helix	trans	-55.4	-47.3	-179.5	-177.2	0	0	0	0	113.8	C324 H325 L330 V331 Y340 Y404	C324-C328 PolarHBondContact O-N 3.4Å; H325-C328 WeakPolarHBondContact O-CB 3.2Å; H325-C328 PolarHBondContact O-N 3.41Å; C328-L330 PolarHBondContact O-N 3.37Å; C328-L330 VanDerWaalsContact O-N 3.08Å; C328-V331 VanDerWaalsContact O-CB 3.28Å; C328-V331 WeakPolarHBondContact O-CB 3.5Å; C328-V331 PolarHBondContact O-N 3.41Å; C328-Y340 HydrophobicContact CB-CD2 3.75Å; C328-Y340 HydrophobicContact CB-CE1 4.35Å; C328-Y340 HydrophobicContact CB-CE2 3.5Å; C328-Y340 HydrophobicContact CB-CG 4.28Å; C328-Y404 HydrophobicContact CB-CD1 3.92Å; C328-Y404 HydrophobicContact CB-CE1 4.25Å; C328-Y404 HydrophobicContact CB-CG 4.25Å
329	P	87.5	Confident	92.3	Very high	3 Å²	3	47.6 Å²	47.6	2%	0.019	26%	0.259	C	S	.	.	G	3₁₀ helix	trans	-58.1	-21.1	178	-31.5	39.4	0	0	0	117	H325 I326 V331 K401 F405	H325-P329 WeakPolarHBondContact O-CD 3.46Å; I326-P329 WeakPolarHBondContact O-CD 3.44Å; P329-V331 PolarHBondContact O-N 3.46Å; P329-K401 HydrophobicContact CB-CB 3.88Å; P329-K401 HydrophobicContact CB-CD 4.34Å; P329-K401 HydrophobicContact CB-CG 3.85Å; P329-K401 HydrophobicContact CG-CB 4.34Å; P329-K401 WeakPolarHBondContact CG-O 3.44Å; P329-K401 WeakPolarHBondContact O-CE 3.19Å; P329-F405 HydrophobicContact CB-CD2 4.36Å; P329-F405 HydrophobicContact CB-CE1 4.35Å; P329-F405 HydrophobicContact CB-CE2 3.7Å; P329-F405 HydrophobicContact CB-CZ 3.69Å; P329-F405 HydrophobicContact CG-CD1 4.33Å; P329-F405 HydrophobicContact CG-CD2 4.08Å; P329-F405 HydrophobicContact CG-CE1 4.14Å; P329-F405 HydrophobicContact CG-CE2 3.89Å; P329-F405 HydrophobicContact CG-CG 4.29Å; P329-F405 HydrophobicContact CG-CZ 3.92Å
330	L	86.6	Confident	92.2	Very high	127 Å²	127	45.1 Å²	45.1	67%	0.665	25%	0.245	S	C	*	.	G	3₁₀ helix	trans	-77.6	-7.8	179.3	-60	173.7	0	0	0	112.1	L327 C328	L327-L330 HydrophobicContact CD2-CD1 3.95Å; L327-L330 WeakPolarHBondContact O-CB 3.37Å; L327-L330 PolarHBondContact O-N 2.86Å; C328-L330 PolarHBondContact O-N 3.37Å; C328-L330 VanDerWaalsContact O-N 3.08Å
331	V	86.5	Confident	92.1	Very high	30 Å²	30	42.5 Å²	42.5	18%	0.182	24%	0.235	C	C	.	.			trans	-100.7	118.7	-174.1	178.1	0	0	0	0	110	C328 P329 G336 L337	C328-V331 VanDerWaalsContact O-CB 3.28Å; C328-V331 WeakPolarHBondContact O-CB 3.5Å; C328-V331 PolarHBondContact O-N 3.41Å; P329-V331 PolarHBondContact O-N 3.46Å; V331-G336 VanDerWaalsContact CG1-CA 3.42Å; V331-L337 HydrophobicContact CG1-CD2 4.21Å; V331-L337 HydrophobicContact CG1-CG 4.16Å; V331-L337 VanDerWaalsContact CG1-N 3.32Å
332	E	81.3	Confident	92.2	Very high	135 Å²	135	45.3 Å²	45.3	63%	0.631	25%	0.252	S	S	*	.			trans	-116.3	-3.1	-178.7	-57.7	-171.2	158.4	0	0	113	K401	E332-K401 IonicContact OE1-NZ 3.08Å; E332-K401 PolarHBondContact OE1-NZ 3.18Å
333	S	89.8	Confident	92.2	Very high	64 Å²	64	50.4 Å²	50.4	45%	0.448	28%	0.275	S	S	.	.	S	Bend	trans	-109.6	150.7	-179.6	68.4	0	0	0	0	112.2	T335 G336 L337	S333-T335 VanDerWaalsContact C-N 3.31Å; S333-T335 PolarHBondContact O-N 3.33Å; S333-G336 PolarHBondContact O-N 3.39Å; S333-G336 VanDerWaalsContact O-N 3.11Å; S333-G336 PolarHBondContact OG-N 2.96Å; S333-G336 VanDerWaalsContact OG-N 3.16Å; S333-L337 PolarHBondContact O-N 3.48Å
334	Y	90.5	Very high	92.2	Very high	78 Å²	78	47.6 Å²	47.6	31%	0.306	26%	0.257	S	S	.	.	H	α-helix	trans	-57.1	-44.7	174.6	177.5	-109.9	0	0	0	112.1	V274 L282 G336 L337 V338	V274-Y334 HydrophobicContact CG1-CD2 3.6Å; V274-Y334 HydrophobicContact CG1-CE2 3.97Å; V274-Y334 HydrophobicContact CG2-CD2 4.2Å; L282-Y334 HydrophobicContact CD2-CE2 4.04Å; L282-Y334 HydrophobicContact CG-CE2 4.26Å; Y334-G336 VanDerWaalsContact C-N 3.26Å; Y334-G336 PolarHBondContact O-N 3.43Å; Y334-L337 WeakPolarHBondContact O-CB 3.47Å; Y334-L337 PolarHBondContact O-N 2.94Å; Y334-V338 HydrophobicContact CD1-CG2 4.25Å; Y334-V338 HydrophobicContact CE1-CG2 3.77Å; Y334-V338 HydrophobicContact CE2-CG2 4.11Å; Y334-V338 WeakPolarHBondContact O-CG2 3.1Å; Y334-V338 PolarHBondContact O-N 3Å
335	T	92	Very high	92.2	Very high	104 Å²	104	47.1 Å²	47.1	64%	0.638	26%	0.255	S	S	*	.	H	α-helix	trans	-57.5	-41.2	176.2	-51.5	0	0	0	0	111.5	S333 V338 V339	S333-T335 VanDerWaalsContact C-N 3.31Å; S333-T335 PolarHBondContact O-N 3.33Å; T335-V338 WeakPolarHBondContact O-CB 3.25Å; T335-V338 PolarHBondContact O-N 3.29Å; T335-V339 WeakPolarHBondContact O-CG2 3.43Å; T335-V339 PolarHBondContact O-N 3.06Å
336	G	93	Very high	92.3	Very high	16 Å²	16	50.1 Å²	50.1	17%	0.165	27%	0.268	C	S	.	.	H	α-helix	trans	-67.6	-36.9	175.3	0	0	0	0	0	112.5	V331 S333 Y334 V338 V339 Y340	V331-G336 VanDerWaalsContact CG1-CA 3.42Å; S333-G336 PolarHBondContact O-N 3.39Å; S333-G336 VanDerWaalsContact O-N 3.11Å; S333-G336 PolarHBondContact OG-N 2.96Å; S333-G336 VanDerWaalsContact OG-N 3.16Å; Y334-G336 VanDerWaalsContact C-N 3.26Å; Y334-G336 PolarHBondContact O-N 3.43Å; G336-V338 VanDerWaalsContact C-N 3.29Å; G336-V338 PolarHBondContact O-N 3.22Å; G336-V339 PolarHBondContact O-N 2.77Å; G336-Y340 PolarHBondContact O-N 3.25Å
337	L	92.8	Very high	92.3	Very high	0 Å²	0	47.5 Å²	47.5	0%	0	25%	0.254	C	S	.	.	H	α-helix	trans	-65	-34.8	175.8	-72.8	175.8	0	0	0	111.5	Y268 A269 I272 V274 L282 V331 S333 Y334 Y340 A341	Y268-L337 HydrophobicContact CD1-CD2 4.21Å; Y268-L337 HydrophobicContact CE1-CD2 3.91Å; A269-L337 HydrophobicContact CB-CD1 4.1Å; I272-L337 HydrophobicContact CD1-CD1 4.17Å; V274-L337 HydrophobicContact CG2-CD1 4.25Å; L282-L337 HydrophobicContact CD1-CB 4.05Å; L282-L337 HydrophobicContact CD1-CD1 4.24Å; L282-L337 HydrophobicContact CD2-CB 4.06Å; V331-L337 HydrophobicContact CG1-CD2 4.21Å; V331-L337 HydrophobicContact CG1-CG 4.16Å; V331-L337 VanDerWaalsContact CG1-N 3.32Å; S333-L337 PolarHBondContact O-N 3.48Å; Y334-L337 WeakPolarHBondContact O-CB 3.47Å; Y334-L337 PolarHBondContact O-N 2.94Å; L337-Y340 PolarHBondContact O-N 2.88Å; L337-A341 WeakPolarHBondContact O-CB 3.36Å; L337-A341 PolarHBondContact O-N 3.3Å
338	V	95.3	Very high	92.4	Very high	37 Å²	37	43.5 Å²	43.5	22%	0.224	23%	0.233	C	C	.	.	H	α-helix	trans	-62.9	-47.4	171.6	169	0	0	0	0	110.7	L282 I285 Y334 T335 G336 Y340 A341 V342	L282-V338 HydrophobicContact CD2-CB 4.49Å; L282-V338 HydrophobicContact CD2-CG2 3.81Å; I285-V338 HydrophobicContact CD1-CB 4.45Å; I285-V338 HydrophobicContact CD1-CG1 3.92Å; I285-V338 HydrophobicContact CD1-CG2 3.97Å; Y334-V338 HydrophobicContact CD1-CG2 4.25Å; Y334-V338 HydrophobicContact CE1-CG2 3.77Å; Y334-V338 HydrophobicContact CE2-CG2 4.11Å; Y334-V338 WeakPolarHBondContact O-CG2 3.1Å; Y334-V338 PolarHBondContact O-N 3Å; T335-V338 WeakPolarHBondContact O-CB 3.25Å; T335-V338 PolarHBondContact O-N 3.29Å; G336-V338 VanDerWaalsContact C-N 3.29Å; G336-V338 PolarHBondContact O-N 3.22Å; V338-Y340 VanDerWaalsContact C-N 3.32Å; V338-Y340 PolarHBondContact O-N 3.29Å; V338-A341 WeakPolarHBondContact O-CB 3.32Å; V338-A341 PolarHBondContact O-N 3.3Å; V338-A341 VanDerWaalsContact O-N 3.16Å; V338-V342 WeakPolarHBondContact O-CG2 3.03Å; V338-V342 PolarHBondContact O-N 3.16Å
339	V	95.8	Very high	92.5	Very high	71 Å²	71	43.5 Å²	43.5	43%	0.43	23%	0.233	S	C	.	.	H	α-helix	trans	-59.9	-43.8	176.1	172.8	0	0	0	0	111	T335 G336 V342 F343	T335-V339 WeakPolarHBondContact O-CG2 3.43Å; T335-V339 PolarHBondContact O-N 3.06Å; G336-V339 PolarHBondContact O-N 2.77Å; V339-V342 PolarHBondContact O-N 2.81Å; V339-F343 HydrophobicContact CG1-CD2 3.72Å; V339-F343 HydrophobicContact CG1-CE2 3.43Å; V339-F343 VanDerWaalsContact CG1-CE2 3.43Å; V339-F343 WeakPolarHBondContact O-CD2 3.32Å; V339-F343 PolarHBondContact O-N 3.35Å; V339-F343 VanDerWaalsContact O-N 3.13Å
340	Y	95.2	Very high	92.8	Very high	12 Å²	12	43.7 Å²	43.7	5%	0.047	23%	0.234	C	C	.	.	H	α-helix	trans	-59.6	-45.4	173.3	166.6	-102.2	0	0	0	112.1	L265 C324 H325 C328 G336 L337 V338 V342 F343 F344	L265-Y340 HydrophobicContact CD1-CD1 4.21Å; L265-Y340 HydrophobicContact CD1-CE1 3.8Å; C324-Y340 HydrophobicContact CB-CE2 4.45Å; C324-Y340 VanDerWaalsContact O-CE2 3.3Å; C324-Y340 WeakPolarHBondContact O-CE2 3.5Å; H325-Y340 PolarHBondContact ND1-OH 3.32Å; C328-Y340 HydrophobicContact CB-CD2 3.75Å; C328-Y340 HydrophobicContact CB-CE1 4.35Å; C328-Y340 HydrophobicContact CB-CE2 3.5Å; C328-Y340 HydrophobicContact CB-CG 4.28Å; G336-Y340 PolarHBondContact O-N 3.25Å; L337-Y340 PolarHBondContact O-N 2.88Å; V338-Y340 VanDerWaalsContact C-N 3.32Å; V338-Y340 PolarHBondContact O-N 3.29Å; Y340-V342 VanDerWaalsContact C-N 3.26Å; Y340-V342 PolarHBondContact O-N 3.24Å; Y340-F343 PolarHBondContact O-N 2.85Å; Y340-F344 HydrophobicContact CE1-CB 4.33Å; Y340-F344 HydrophobicContact CE1-CD1 4.04Å; Y340-F344 HydrophobicContact CE2-CB 4.07Å; Y340-F344 AromaticContact CZ-CD1 3.9Å; Y340-F344 VanDerWaalsContact O-CB 3.25Å; Y340-F344 WeakPolarHBondContact O-CB 3.41Å; Y340-F344 PolarHBondContact O-N 3.44Å
341	A	95.1	Very high	93.2	Very high	0 Å²	0	37.8 Å²	37.8	0%	0	20%	0.203	C	C	.	.	H	α-helix	trans	-60.8	-35.3	179.2	0	0	0	0	0	112.2	L282 I285 L286 L337 V338 G345	L282-A341 HydrophobicContact CD2-CB 4.31Å; I285-A341 HydrophobicContact CG2-CB 4.28Å; L286-A341 HydrophobicContact CB-CB 4.46Å; L337-A341 WeakPolarHBondContact O-CB 3.36Å; L337-A341 PolarHBondContact O-N 3.3Å; V338-A341 WeakPolarHBondContact O-CB 3.32Å; V338-A341 PolarHBondContact O-N 3.3Å; V338-A341 VanDerWaalsContact O-N 3.16Å; A341-G345 PolarHBondContact O-N 3.04Å
342	V	96.8	Very high	93.3	Very high	59 Å²	59	37.6 Å²	37.6	36%	0.358	20%	0.203	S	C	.	.	H	α-helix	trans	-65	-53	173.7	172.3	0	0	0	0	111.1	I285 V289 V338 V339 Y340 F344 G345 F346	I285-V342 HydrophobicContact CG2-CG2 3.78Å; V289-V342 HydrophobicContact CG1-CG1 4.48Å; V289-V342 WeakPolarHBondContact CG1-O 3.46Å; V289-V342 HydrophobicContact CG2-CB 4.35Å; V289-V342 HydrophobicContact CG2-CG1 4.15Å; V289-V342 HydrophobicContact CG2-CG2 4.16Å; V338-V342 WeakPolarHBondContact O-CG2 3.03Å; V338-V342 PolarHBondContact O-N 3.16Å; V339-V342 PolarHBondContact O-N 2.81Å; Y340-V342 VanDerWaalsContact C-N 3.26Å; Y340-V342 PolarHBondContact O-N 3.24Å; V342-F344 VanDerWaalsContact C-N 3.35Å; V342-F344 PolarHBondContact O-N 3.44Å; V342-G345 PolarHBondContact O-N 2.85Å; V342-F346 PolarHBondContact O-N 3.13Å
343	F	96.5	Very high	93.6	Very high	108 Å²	108	31.9 Å²	31.9	47%	0.474	18%	0.178	S	C	.	.	H	α-helix	trans	-64.6	-40.1	-179.2	-73	-60.9	0	0	0	112.5	Y320 V339 Y340 F346 A347	Y320-F343 WeakPolarHBondContact OH-CD1 3.32Å; Y320-F343 PolarHBondContact OH-O 3.15Å; V339-F343 HydrophobicContact CG1-CD2 3.72Å; V339-F343 HydrophobicContact CG1-CE2 3.43Å; V339-F343 VanDerWaalsContact CG1-CE2 3.43Å; V339-F343 WeakPolarHBondContact O-CD2 3.32Å; V339-F343 PolarHBondContact O-N 3.35Å; V339-F343 VanDerWaalsContact O-N 3.13Å; Y340-F343 PolarHBondContact O-N 2.85Å; F343-F346 PolarHBondContact O-N 2.87Å; F343-A347 WeakPolarHBondContact O-CB 3.23Å; F343-A347 PolarHBondContact O-N 3.42Å
344	F	95.5	Very high	93.6	Very high	0 Å²	0	28.9 Å²	28.9	0%	0	16%	0.157	C	C	.	.	H	α-helix	trans	-66.9	-42.4	176.1	179.4	-148.2	0	0	0	111.8	P261 I262 L286 H325 Y340 V342 F346 A347 F348	P261-F344 HydrophobicContact CB-CZ 4.46Å; I262-F344 HydrophobicContact CB-CE1 3.85Å; I262-F344 HydrophobicContact CB-CZ 3.88Å; I262-F344 HydrophobicContact CG1-CE1 4.42Å; L286-F344 HydrophobicContact CD1-CD1 3.27Å; L286-F344 HydrophobicContact CD1-CE1 3.47Å; L286-F344 VanDerWaalsContact CD1-CE1 3.47Å; L286-F344 HydrophobicContact CD1-CG 4.1Å; L286-F344 HydrophobicContact CD1-CZ 4.41Å; L286-F344 HydrophobicContact CG-CD1 4.34Å; H325-F344 AromaticContact CE1-CD2 3.54Å; H325-F344 AromaticContact CE1-CE2 3.23Å; H325-F344 WeakPolarHBondContact CE1-CE2 3.35Å; H325-F344 AromaticContact CE1-CZ 3.53Å; H325-F344 AromaticContact NE2-CE2 3.66Å; Y340-F344 HydrophobicContact CE1-CB 4.33Å; Y340-F344 HydrophobicContact CE1-CD1 4.04Å; Y340-F344 HydrophobicContact CE2-CB 4.07Å; Y340-F344 AromaticContact CZ-CD1 3.9Å; Y340-F344 VanDerWaalsContact O-CB 3.25Å; Y340-F344 WeakPolarHBondContact O-CB 3.41Å; Y340-F344 PolarHBondContact O-N 3.44Å; V342-F344 VanDerWaalsContact C-N 3.35Å; V342-F344 PolarHBondContact O-N 3.44Å; F344-F346 VanDerWaalsContact C-N 3.32Å; F344-F346 PolarHBondContact O-N 3.23Å; F344-A347 PolarHBondContact O-N 3.33Å; F344-F348 HydrophobicContact CD2-CB 4.49Å; F344-F348 HydrophobicContact CE2-CB 4.29Å; F344-F348 HydrophobicContact CE2-CD2 4.14Å; F344-F348 HydrophobicContact CZ-CD2 4.33Å; F344-F348 VanDerWaalsContact O-CB 3.24Å; F344-F348 WeakPolarHBondContact O-CB 3.45Å; F344-F348 PolarHBondContact O-N 3.09Å
345	G	95.4	Very high	93.6	Very high	0 Å²	0	25.9 Å²	25.9	0%	0	15%	0.146	C	C	.	.	H	α-helix	trans	-59.9	-41.6	174.6	0	0	0	0	0	112.5	A341 V342 F348 G349	A341-G345 PolarHBondContact O-N 3.04Å; V342-G345 PolarHBondContact O-N 2.85Å; G345-F348 PolarHBondContact O-N 3.33Å; G345-G349 PolarHBondContact O-N 3.26Å
346	F	96.3	Very high	93.3	Very high	63 Å²	63	23.9 Å²	23.9	28%	0.276	13%	0.129	S	C	.	.	H	α-helix	trans	-64	-45.9	174.2	-173.5	-101.6	0	0	0	112.1	V289 A293 M297 Y320 V342 F343 F344 F348 G349 M350	V289-F346 HydrophobicContact CG1-CB 3.95Å; A293-F346 HydrophobicContact CB-CB 4.47Å; A293-F346 HydrophobicContact CB-CD2 3.58Å; A293-F346 HydrophobicContact CB-CE2 4.16Å; A293-F346 HydrophobicContact CB-CG 4.29Å; M297-F346 HydrophobicContact CE-CE2 3.96Å; M297-F346 HydrophobicContact CE-CZ 3.68Å; M297-F346 HydrophobicContact CG-CE2 4.35Å; M297-F346 HydrophobicContact CG-CZ 4.18Å; M297-F346 HydrophobicContact SD-CE1 4.48Å; M297-F346 HydrophobicContact SD-CE2 4.36Å; M297-F346 HydrophobicContact SD-CZ 3.74Å; Y320-F346 AromaticContact CE1-CD1 3.81Å; Y320-F346 HydrophobicContact CE1-CD1 3.81Å; V342-F346 PolarHBondContact O-N 3.13Å; F343-F346 PolarHBondContact O-N 2.87Å; F344-F346 VanDerWaalsContact C-N 3.32Å; F344-F346 PolarHBondContact O-N 3.23Å; F346-F348 PolarHBondContact O-N 3.32Å; F346-G349 PolarHBondContact O-N 2.97Å; F346-M350 HydrophobicContact CD1-CE 4.2Å; F346-M350 HydrophobicContact CE1-CE 3.41Å; F346-M350 VanDerWaalsContact CE1-CE 3.41Å; F346-M350 HydrophobicContact CZ-CE 3.93Å; F346-M350 WeakPolarHBondContact O-CB 3.32Å; F346-M350 PolarHBondContact O-N 3.47Å
347	A	95.8	Very high	92.8	Very high	0 Å²	0	25.2 Å²	25.2	0%	0	13%	0.13	C	C	.	.	H	α-helix	trans	-61.5	-44.8	177.1	0	0	0	0	0	112	Y320 N321 F343 F344 M350 V351	Y320-A347 HydrophobicContact CD1-CB 3.45Å; Y320-A347 VanDerWaalsContact CD1-CB 3.45Å; Y320-A347 HydrophobicContact CE1-CB 3.41Å; Y320-A347 VanDerWaalsContact CE1-CB 3.41Å; N321-A347 HydrophobicContact CB-CB 3.92Å; F343-A347 WeakPolarHBondContact O-CB 3.23Å; F343-A347 PolarHBondContact O-N 3.42Å; F344-A347 PolarHBondContact O-N 3.33Å; A347-M350 PolarHBondContact O-N 3.14Å; A347-V351 WeakPolarHBondContact O-CG2 3.38Å; A347-V351 PolarHBondContact O-N 3.32Å
348	F	93.4	Very high	92.6	Very high	6 Å²	6	25.3 Å²	25.3	3%	0.026	13%	0.131	C	C	.	.	H	α-helix	trans	-62.7	-43.5	179.8	-170.3	-85.5	0	0	0	111.2	F258 F259 F344 G345 F346 S352	F258-F348 HydrophobicContact CD1-CE2 4.15Å; F258-F348 AromaticContact CE1-CD2 3.82Å; F258-F348 HydrophobicContact CE1-CD2 3.82Å; F258-F348 AromaticContact CE1-CE2 3.24Å; F258-F348 HydrophobicContact CE1-CE2 3.24Å; F258-F348 AromaticContact CE1-CZ 3.89Å; F258-F348 HydrophobicContact CE1-CZ 3.89Å; F258-F348 HydrophobicContact CE2-CD2 4.08Å; F258-F348 HydrophobicContact CE2-CE2 4.34Å; F258-F348 AromaticContact CZ-CD2 3.4Å; F258-F348 HydrophobicContact CZ-CD2 3.4Å; F258-F348 AromaticContact CZ-CE2 3.36Å; F258-F348 HydrophobicContact CZ-CE2 3.36Å; F258-F348 HydrophobicContact CZ-CG 4.23Å; F258-F348 HydrophobicContact CZ-CZ 4.15Å; F259-F348 HydrophobicContact CE1-CE2 4.45Å; F259-F348 HydrophobicContact CE1-CZ 4.39Å; F344-F348 HydrophobicContact CD2-CB 4.49Å; F344-F348 HydrophobicContact CE2-CB 4.29Å; F344-F348 HydrophobicContact CE2-CD2 4.14Å; F344-F348 HydrophobicContact CZ-CD2 4.33Å; F344-F348 VanDerWaalsContact O-CB 3.24Å; F344-F348 WeakPolarHBondContact O-CB 3.45Å; F344-F348 PolarHBondContact O-N 3.09Å; G345-F348 PolarHBondContact O-N 3.33Å; F346-F348 PolarHBondContact O-N 3.32Å; F348-S352 WeakPolarHBondContact CE1-OG 3.42Å; F348-S352 VanDerWaalsContact O-CB 3.27Å; F348-S352 WeakPolarHBondContact O-CB 3.28Å; F348-S352 PolarHBondContact O-N 3.46Å; F348-S352 PolarHBondContact O-OG 3.39Å
349	G	91.9	Very high	92.2	Very high	0 Å²	0	23.6 Å²	23.6	0%	0	12%	0.12	C	C	.	.	H	α-helix	trans	-64.8	-40.7	175.9	0	0	0	0	0	113.1	D290 G345 F346 S352 S353	D290-G349 WeakPolarHBondContact OD1-CA 3.34Å; G345-G349 PolarHBondContact O-N 3.26Å; F346-G349 PolarHBondContact O-N 2.97Å; G349-S352 PolarHBondContact O-N 3.18Å; G349-S353 PolarHBondContact O-N 3.25Å; G349-S353 PolarHBondContact O-OG 3.45Å; G349-S353 VanDerWaalsContact O-OG 3.13Å
350	M	93.8	Very high	91.5	Very high	8 Å²	8	24.1 Å²	24.1	4%	0.039	12%	0.119	C	C	.	.	H	α-helix	trans	-62.3	-48.2	176	-170.7	-171.9	-74	0	0	112.3	M297 F313 F316 A317 F346 A347 S353 V354	M297-M350 HydrophobicContact CB-CB 4.33Å; M297-M350 HydrophobicContact CB-CG 4.13Å; M297-M350 HydrophobicContact CG-CB 3.96Å; M297-M350 HydrophobicContact CG-CE 4.08Å; M297-M350 HydrophobicContact CG-CG 3.92Å; M297-M350 HydrophobicContact SD-CE 3.55Å; M297-M350 VanDerWaalsContact SD-CE 3.55Å; M297-M350 HydrophobicContact SD-CG 4.36Å; F313-M350 HydrophobicContact CE1-CG 4.49Å; F313-M350 HydrophobicContact CZ-CG 4.26Å; F313-M350 HydrophobicContact CZ-SD 4.3Å; F316-M350 HydrophobicContact CD1-SD 4.46Å; A317-M350 HydrophobicContact CB-CB 4.29Å; A317-M350 HydrophobicContact CB-CG 3.58Å; A317-M350 HydrophobicContact CB-SD 3.43Å; A317-M350 WeakPolarHBondContact CB-SD 3.13Å; F346-M350 HydrophobicContact CD1-CE 4.2Å; F346-M350 HydrophobicContact CE1-CE 3.41Å; F346-M350 VanDerWaalsContact CE1-CE 3.41Å; F346-M350 HydrophobicContact CZ-CE 3.93Å; F346-M350 WeakPolarHBondContact O-CB 3.32Å; F346-M350 PolarHBondContact O-N 3.47Å; A347-M350 PolarHBondContact O-N 3.14Å; M350-S353 PolarHBondContact O-OG 3.48Å; M350-V354 VanDerWaalsContact O-CG2 3.27Å; M350-V354 WeakPolarHBondContact O-CG2 3.5Å; M350-V354 PolarHBondContact O-N 3.38Å
351	V	94	Very high	91.1	Very high	3 Å²	3	26.9 Å²	26.9	2%	0.018	14%	0.135	C	C	.	.	H	α-helix	trans	-62	-46	176.4	173.2	0	0	0	0	110.1	M254 F258 F314 A317 V318 N321 A347 S353 V354 L355	M254-V351 HydrophobicContact CE-CG1 4.47Å; M254-V351 HydrophobicContact SD-CG1 4.13Å; F258-V351 HydrophobicContact CE2-CB 4.22Å; F258-V351 HydrophobicContact CE2-CG1 3.98Å; F258-V351 HydrophobicContact CE2-CG2 4.41Å; F258-V351 HydrophobicContact CZ-CB 4.23Å; F258-V351 HydrophobicContact CZ-CG1 3.93Å; F314-V351 HydrophobicContact CE2-CG1 4.13Å; A317-V351 HydrophobicContact CB-CG2 3.89Å; V318-V351 HydrophobicContact CG2-CG2 4.24Å; N321-V351 HydrophobicContact CB-CG2 4.36Å; A347-V351 WeakPolarHBondContact O-CG2 3.38Å; A347-V351 PolarHBondContact O-N 3.32Å; V351-S353 PolarHBondContact O-N 3.02Å; V351-V354 PolarHBondContact O-N 2.9Å; V351-L355 VanDerWaalsContact O-CB 3.31Å; V351-L355 WeakPolarHBondContact O-CB 3.41Å; V351-L355 PolarHBondContact O-N 3.06Å
352	S	89.2	Confident	90.6	Very high	25 Å²	25	27.8 Å²	27.8	18%	0.175	14%	0.14	C	C	.	.	H	α-helix	trans	-64.2	-35.9	-177.5	-60.6	0	0	0	0	113.5	F348 G349	F348-S352 WeakPolarHBondContact CE1-OG 3.42Å; F348-S352 VanDerWaalsContact O-CB 3.27Å; F348-S352 WeakPolarHBondContact O-CB 3.28Å; F348-S352 PolarHBondContact O-N 3.46Å; F348-S352 PolarHBondContact O-OG 3.39Å; G349-S352 PolarHBondContact O-N 3.18Å
353	S	87.8	Confident	89.9	Confident	16 Å²	16	26.1 Å²	26.1	11%	0.112	13%	0.129	C	C	.	.	H	α-helix	trans	-70.5	-42.5	176.5	53.7	0	0	0	0	112.1	R294 G349 M350 V351	R294-S353 WeakPolarHBondContact O-CB 3.43Å; G349-S353 PolarHBondContact O-N 3.25Å; G349-S353 PolarHBondContact O-OG 3.45Å; G349-S353 VanDerWaalsContact O-OG 3.13Å; M350-S353 PolarHBondContact O-OG 3.48Å; V351-S353 PolarHBondContact O-N 3.02Å
354	V	90.4	Very high	88.9	Confident	0 Å²	0	22.3 Å²	22.3	0%	0	12%	0.121	C	C	.	.	H	α-helix	trans	-84.3	-22.2	-171.1	-177.7	0	0	0	0	112.3	A301 I310 F313 F314 M350 V351 F356 E357 T358	A301-V354 HydrophobicContact CB-CG2 4.23Å; I310-V354 HydrophobicContact CG1-CG1 4.05Å; F313-V354 HydrophobicContact CD1-CG1 4.22Å; F313-V354 HydrophobicContact CD1-CG2 3.67Å; F313-V354 HydrophobicContact CE1-CG2 3.51Å; F314-V354 HydrophobicContact CB-CG1 3.69Å; F314-V354 HydrophobicContact CD2-CB 4.12Å; F314-V354 HydrophobicContact CD2-CG1 3.89Å; F314-V354 HydrophobicContact CG-CG1 4.23Å; M350-V354 VanDerWaalsContact O-CG2 3.27Å; M350-V354 WeakPolarHBondContact O-CG2 3.5Å; M350-V354 PolarHBondContact O-N 3.38Å; V351-V354 PolarHBondContact O-N 2.9Å; V354-F356 PolarHBondContact O-N 3.46Å; V354-E357 PolarHBondContact O-N 3.39Å; V354-T358 HydrophobicContact CG1-CG2 3.77Å; V354-T358 PolarHBondContact O-N 3.48Å; V354-T358 PolarHBondContact O-OG1 3.34Å
355	L	90.6	Very high	87.7	Confident	15 Å²	15	25.9 Å²	25.9	8%	0.079	15%	0.15	C	C	.	.	H	α-helix	trans	-52.6	-52.6	-177.9	-174.6	75	0	0	0	112.9	Y247 M254 F255 F314 V351 T358 L359	Y247-L355 WeakPolarHBondContact OH-CD1 3.41Å; Y247-L355 PolarHBondContact OH-O 3.06Å; M254-L355 HydrophobicContact CE-CD1 4.3Å; F255-L355 HydrophobicContact CZ-CD2 4.1Å; F314-L355 HydrophobicContact CE2-CB 4.27Å; F314-L355 HydrophobicContact CE2-CD1 3.85Å; F314-L355 HydrophobicContact CZ-CD1 3.62Å; V351-L355 VanDerWaalsContact O-CB 3.31Å; V351-L355 WeakPolarHBondContact O-CB 3.41Å; V351-L355 PolarHBondContact O-N 3.06Å; L355-T358 PolarHBondContact O-OG1 2.83Å; L355-L359 PolarHBondContact O-N 3.44Å
356	F	84.1	Confident	86.4	Confident	63 Å²	63	33.7 Å²	33.7	28%	0.276	19%	0.187	S	C	.	.	H	α-helix	trans	-81.8	-27.3	-177.9	-67.5	-63.5	0	0	0	113	V354 L359 M360 F368 V372	V354-F356 PolarHBondContact O-N 3.46Å; F356-L359 PolarHBondContact O-N 3.37Å; F356-M360 WeakPolarHBondContact O-CB 3.37Å; F356-M360 PolarHBondContact O-N 3.11Å; F356-F368 HydrophobicContact CB-CZ 4.27Å; F356-F368 HydrophobicContact CD1-CZ 4.48Å; F356-F368 WeakPolarHBondContact O-CE2 3.34Å; F356-V372 HydrophobicContact CD1-CG2 4.23Å; F356-V372 HydrophobicContact CE1-CG1 4.22Å; F356-V372 HydrophobicContact CE1-CG2 4.43Å
357	E	84.1	Confident	85.4	Confident	44 Å²	44	36.7 Å²	36.7	21%	0.206	20%	0.196	C	C	.	.	H	α-helix	trans	-67.7	-42.6	175.5	-69.1	-169.6	158.6	0	0	111.6	A301 N302 I310 V354 M360 D361	A301-E357 VanDerWaalsContact CB-OE2 3.24Å; A301-E357 WeakPolarHBondContact CB-OE2 3.36Å; N302-E357 PolarHBondContact ND2-OE1 2.9Å; I310-E357 HydrophobicContact CD1-CB 3.72Å; V354-E357 PolarHBondContact O-N 3.39Å; E357-M360 PolarHBondContact O-N 3.43Å; E357-D361 WeakPolarHBondContact O-CB 3.34Å; E357-D361 PolarHBondContact O-N 3.45Å
358	T	88.5	Confident	84.4	Confident	2 Å²	2	39 Å²	39	1%	0.012	21%	0.206	C	C	.	.	H	α-helix	trans	-62.3	-42	173.4	40.4	0	0	0	0	112.1	Y247 I310 F314 V354 L355 M360 D361 L362	Y247-T358 WeakPolarHBondContact CE2-OG1 3.22Å; I310-T358 HydrophobicContact CB-CG2 4.47Å; I310-T358 HydrophobicContact CD1-CG2 4.46Å; I310-T358 HydrophobicContact CG1-CG2 3.91Å; I310-T358 HydrophobicContact CG2-CG2 4.18Å; F314-T358 HydrophobicContact CB-CG2 3.7Å; F314-T358 HydrophobicContact CG-CG2 4.16Å; V354-T358 HydrophobicContact CG1-CG2 3.77Å; V354-T358 PolarHBondContact O-N 3.48Å; V354-T358 PolarHBondContact O-OG1 3.34Å; L355-T358 PolarHBondContact O-OG1 2.83Å; T358-M360 VanDerWaalsContact C-N 3.32Å; T358-M360 PolarHBondContact O-N 2.96Å; T358-D361 PolarHBondContact O-N 3.31Å; T358-L362 VanDerWaalsContact O-CB 3.24Å; T358-L362 WeakPolarHBondContact O-CB 3.35Å; T358-L362 PolarHBondContact O-N 2.85Å
359	L	86.7	Confident	83.3	Confident	0 Å²	0	43.2 Å²	43.2	0%	0	24%	0.237	C	C	.	.	H	α-helix	trans	-62.5	-40.7	175.8	-177	59.2	0	0	0	112	F244 Y247 L355 F356 L362 V363 F368 A371 V372	F244-L359 HydrophobicContact CD2-CD1 3.9Å; F244-L359 HydrophobicContact CE2-CD1 3.88Å; Y247-L359 HydrophobicContact CD1-CD1 4.02Å; Y247-L359 HydrophobicContact CE1-CB 4.2Å; Y247-L359 HydrophobicContact CE1-CD1 3.78Å; Y247-L359 HydrophobicContact CE1-CD2 4.44Å; Y247-L359 HydrophobicContact CE1-CG 4.36Å; L355-L359 PolarHBondContact O-N 3.44Å; F356-L359 PolarHBondContact O-N 3.37Å; L359-L362 PolarHBondContact O-N 3.43Å; L359-V363 HydrophobicContact CD1-CG2 4Å; L359-V363 WeakPolarHBondContact O-CB 3.46Å; L359-V363 PolarHBondContact O-N 3.34Å; L359-V363 VanDerWaalsContact O-N 3.08Å; L359-F368 HydrophobicContact CB-CE2 4.27Å; L359-F368 HydrophobicContact CD2-CE2 4.31Å; L359-F368 HydrophobicContact CG-CD2 4.38Å; L359-F368 HydrophobicContact CG-CE2 4.2Å; L359-A371 HydrophobicContact CD1-CB 4.13Å; L359-A371 HydrophobicContact CG-CB 4.47Å; L359-V372 HydrophobicContact CD2-CB 4.5Å; L359-V372 HydrophobicContact CD2-CG2 3.73Å
360	M	81.6	Confident	82.6	Confident	83 Å²	83	44.3 Å²	44.3	41%	0.409	24%	0.244	S	C	.	.	H	α-helix	trans	-65.7	-40.8	177.4	-172.2	178	177.1	0	0	112.4	F356 E357 T358 L362 G364 A365 F368	F356-M360 WeakPolarHBondContact O-CB 3.37Å; F356-M360 PolarHBondContact O-N 3.11Å; E357-M360 PolarHBondContact O-N 3.43Å; T358-M360 VanDerWaalsContact C-N 3.32Å; T358-M360 PolarHBondContact O-N 2.96Å; M360-L362 VanDerWaalsContact C-N 3.33Å; M360-G364 VanDerWaalsContact O-CA 3.22Å; M360-G364 WeakPolarHBondContact O-CA 3.4Å; M360-G364 PolarHBondContact O-N 3.14Å; M360-A365 HydrophobicContact CE-CB 3.96Å; M360-F368 HydrophobicContact CB-CD2 3.7Å; M360-F368 HydrophobicContact CB-CE2 3.68Å; M360-F368 HydrophobicContact CG-CD2 4.11Å; M360-F368 HydrophobicContact CG-CE2 4.41Å
361	D	85	Confident	82.1	Confident	69 Å²	69	44 Å²	44	37%	0.369	24%	0.243	S	C	.	.	H	α-helix	trans	-65.6	-38.1	177	-167.9	70.9	0	0	0	111.9	I310 E357 T358	I310-D361 HydrophobicContact CG2-CB 4.17Å; E357-D361 WeakPolarHBondContact O-CB 3.34Å; E357-D361 PolarHBondContact O-N 3.45Å; T358-D361 PolarHBondContact O-N 3.31Å
362	L	85	Confident	81.6	Confident	20 Å²	20	45.2 Å²	45.2	11%	0.105	25%	0.25	C	S	.	.	H	α-helix	trans	-74.9	-39.7	-176.3	-170	70.7	0	0	0	114.1	H241 G243 F244 Y247 T358 L359 M360	H241-L362 PolarHBondContact CE1-O 3.31Å; H241-L362 VanDerWaalsContact CE1-O 3.24Å; G243-L362 WeakPolarHBondContact O-CD2 3.49Å; F244-L362 HydrophobicContact CB-CD2 4.39Å; Y247-L362 HydrophobicContact CG-CD2 4.04Å; T358-L362 VanDerWaalsContact O-CB 3.24Å; T358-L362 WeakPolarHBondContact O-CB 3.35Å; T358-L362 PolarHBondContact O-N 2.85Å; L359-L362 PolarHBondContact O-N 3.43Å; M360-L362 VanDerWaalsContact C-N 3.33Å
363	V	83.1	Confident	81.2	Confident	23 Å²	23	45 Å²	45	14%	0.139	25%	0.252	C	S	.	.	H	α-helix	trans	-104.6	-20.6	-172.6	173.4	0	0	0	0	112.2	L238 F244 L359 R367 A371	L238-V363 HydrophobicContact CD2-CB 4.5Å; L238-V363 HydrophobicContact CD2-CG1 3.55Å; L238-V363 HydrophobicContact CD2-CG2 4.11Å; F244-V363 HydrophobicContact CB-CG2 4.36Å; F244-V363 HydrophobicContact CD2-CG2 3.79Å; F244-V363 HydrophobicContact CG-CG2 4.41Å; L359-V363 HydrophobicContact CD1-CG2 4Å; L359-V363 WeakPolarHBondContact O-CB 3.46Å; L359-V363 PolarHBondContact O-N 3.34Å; L359-V363 VanDerWaalsContact O-N 3.08Å; V363-R367 HydrophobicContact CG1-CB 3.39Å; V363-A371 HydrophobicContact CB-CB 4.3Å; V363-A371 HydrophobicContact CG1-CB 3.88Å; V363-A371 HydrophobicContact CG2-CB 4.03Å
364	G	75.6	Confident	81.1	Confident	29 Å²	29	44.8 Å²	44.8	30%	0.299	25%	0.25	S	C	.	.			trans	80.3	160.6	-175.6	0	0	0	0	0	113.6	M360 Q366 R367 F368	M360-G364 VanDerWaalsContact O-CA 3.22Å; M360-G364 WeakPolarHBondContact O-CA 3.4Å; M360-G364 PolarHBondContact O-N 3.14Å; G364-Q366 VanDerWaalsContact C-N 3.31Å; G364-Q366 PolarHBondContact O-N 2.92Å; G364-R367 PolarHBondContact O-N 3.34Å; G364-F368 PolarHBondContact O-N 2.95Å; G364-F368 VanDerWaalsContact O-N 3.16Å
365	A	70.2	Confident	81	Confident	74 Å²	74	44.9 Å²	44.9	61%	0.612	25%	0.25	S	S	*	.	T	Hydrogen-bonded Turn	trans	-62.5	-32.4	-171.7	0	0	0	0	0	114.2	M360	M360-A365 HydrophobicContact CE-CB 3.96Å
366	Q	68.7	Low	80.8	Confident	164 Å²	164	45.2 Å²	45.2	77%	0.766	25%	0.253	S	S	*	.	T	Hydrogen-bonded Turn	trans	-70.3	-39.5	-176.2	-68.7	-168.9	-14.3	0	0	112.8	G364	G364-Q366 VanDerWaalsContact C-N 3.31Å; G364-Q366 PolarHBondContact O-N 2.92Å
367	R	75.2	Confident	81	Confident	127 Å²	127	44.8 Å²	44.8	48%	0.479	25%	0.253	S	S	.	.	T	Hydrogen-bonded Turn	trans	-97	-2.6	-177.8	-66.8	-176	-173.3	-164.9	1.2	113.3	S237 L238 V363 G364 S369 S370 A371	S237-R367 PolarHBondContact OG-NH1 3.46Å; L238-R367 HydrophobicContact CD2-CB 4.43Å; V363-R367 HydrophobicContact CG1-CB 3.39Å; G364-R367 PolarHBondContact O-N 3.34Å; R367-S369 PolarHBondContact O-N 3.01Å; R367-S370 PolarHBondContact O-N 3.13Å; R367-A371 PolarHBondContact O-N 3.32Å
368	F	73.5	Confident	81.3	Confident	47 Å²	47	44.8 Å²	44.8	21%	0.206	26%	0.256	C	S	.	.	H	α-helix	trans	-54.3	-46	-176.4	-178.2	-108	0	0	0	113.8	F356 L359 M360 G364 S370 A371 V372	F356-F368 HydrophobicContact CB-CZ 4.27Å; F356-F368 HydrophobicContact CD1-CZ 4.48Å; F356-F368 WeakPolarHBondContact O-CE2 3.34Å; L359-F368 HydrophobicContact CB-CE2 4.27Å; L359-F368 HydrophobicContact CD2-CE2 4.31Å; L359-F368 HydrophobicContact CG-CD2 4.38Å; L359-F368 HydrophobicContact CG-CE2 4.2Å; M360-F368 HydrophobicContact CB-CD2 3.7Å; M360-F368 HydrophobicContact CB-CE2 3.68Å; M360-F368 HydrophobicContact CG-CD2 4.11Å; M360-F368 HydrophobicContact CG-CE2 4.41Å; G364-F368 PolarHBondContact O-N 2.95Å; G364-F368 VanDerWaalsContact O-N 3.16Å; F368-S370 VanDerWaalsContact C-N 3.31Å; F368-S370 PolarHBondContact O-N 3.46Å; F368-A371 PolarHBondContact O-N 2.87Å; F368-V372 HydrophobicContact CD1-CG2 4.16Å; F368-V372 HydrophobicContact CD2-CG2 4.13Å; F368-V372 HydrophobicContact CE1-CG2 3.75Å; F368-V372 HydrophobicContact CE2-CG2 3.73Å; F368-V372 HydrophobicContact CG-CG2 4.35Å; F368-V372 HydrophobicContact CZ-CG2 3.52Å; F368-V372 WeakPolarHBondContact O-CG2 3.24Å; F368-V372 PolarHBondContact O-N 3.44Å
369	S	70.6	Confident	81.4	Confident	96 Å²	96	44.9 Å²	44.9	67%	0.671	26%	0.256	S	S	*	.	H	α-helix	trans	-63.8	-36.1	-178	-171.1	0	0	0	0	113	R367 G373	R367-S369 PolarHBondContact O-N 3.01Å; S369-G373 PolarHBondContact O-N 3.29Å
370	S	78.1	Confident	81.6	Confident	23 Å²	23	45.9 Å²	45.9	16%	0.161	26%	0.263	C	S	.	.	H	α-helix	trans	-71.6	-43.5	176.7	179.3	0	0	0	0	110.4	F233 D235 R367 F368 G373 L374	F233-S370 PolarHBondContact O-OG 3.22Å; D235-S370 VanDerWaalsContact CB-OG 3.23Å; D235-S370 WeakPolarHBondContact CB-OG 3.42Å; D235-S370 PolarHBondContact N-OG 3.2Å; R367-S370 PolarHBondContact O-N 3.13Å; F368-S370 VanDerWaalsContact C-N 3.31Å; F368-S370 PolarHBondContact O-N 3.46Å; S370-G373 PolarHBondContact O-N 2.84Å; S370-L374 PolarHBondContact O-N 3.16Å
371	A	82.6	Confident	82.2	Confident	0 Å²	0	45.4 Å²	45.4	0%	0	27%	0.267	C	S	.	.	H	α-helix	trans	-63.6	-43.2	178.5	0	0	0	0	0	112.9	L238 F244 L359 V363 R367 F368 G373 L374 T375	L238-A371 HydrophobicContact CD1-CB 3.92Å; L238-A371 HydrophobicContact CD2-CB 4.3Å; F244-A371 HydrophobicContact CD2-CB 4.49Å; F244-A371 HydrophobicContact CE2-CB 3.96Å; L359-A371 HydrophobicContact CD1-CB 4.13Å; L359-A371 HydrophobicContact CG-CB 4.47Å; V363-A371 HydrophobicContact CB-CB 4.3Å; V363-A371 HydrophobicContact CG1-CB 3.88Å; V363-A371 HydrophobicContact CG2-CB 4.03Å; R367-A371 PolarHBondContact O-N 3.32Å; F368-A371 PolarHBondContact O-N 2.87Å; A371-G373 VanDerWaalsContact C-N 3.34Å; A371-G373 PolarHBondContact O-N 3.08Å; A371-L374 PolarHBondContact O-N 3.43Å; A371-T375 VanDerWaalsContact O-CB 3.25Å; A371-T375 WeakPolarHBondContact O-CB 3.4Å; A371-T375 PolarHBondContact O-N 3.11Å; A371-T375 PolarHBondContact O-OG1 2.9Å
372	V	82.4	Confident	82.6	Confident	30 Å²	30	42.5 Å²	42.5	18%	0.182	25%	0.252	C	S	.	.	H	α-helix	trans	-57.5	-48.4	174	170.8	0	0	0	0	110.6	F356 L359 F368 L374 T375 T376	F356-V372 HydrophobicContact CD1-CG2 4.23Å; F356-V372 HydrophobicContact CE1-CG1 4.22Å; F356-V372 HydrophobicContact CE1-CG2 4.43Å; L359-V372 HydrophobicContact CD2-CB 4.5Å; L359-V372 HydrophobicContact CD2-CG2 3.73Å; F368-V372 HydrophobicContact CD1-CG2 4.16Å; F368-V372 HydrophobicContact CD2-CG2 4.13Å; F368-V372 HydrophobicContact CE1-CG2 3.75Å; F368-V372 HydrophobicContact CE2-CG2 3.73Å; F368-V372 HydrophobicContact CG-CG2 4.35Å; F368-V372 HydrophobicContact CZ-CG2 3.52Å; F368-V372 WeakPolarHBondContact O-CG2 3.24Å; F368-V372 PolarHBondContact O-N 3.44Å; V372-L374 PolarHBondContact O-N 2.92Å; V372-T375 PolarHBondContact O-N 3.1Å; V372-T376 HydrophobicContact CG1-CG2 4.31Å; V372-T376 WeakPolarHBondContact O-CG2 3.35Å; V372-T376 PolarHBondContact O-N 3.2Å; V372-T376 PolarHBondContact O-OG1 2.99Å; V372-T376 VanDerWaalsContact O-OG1 3.07Å
373	G	81.6	Confident	83	Confident	21 Å²	21	41.6 Å²	41.6	22%	0.216	25%	0.247	C	C	.	.	H	α-helix	trans	-58.9	-48	179.1	0	0	0	0	0	112.4	S369 S370 A371 T376 I377	S369-G373 PolarHBondContact O-N 3.29Å; S370-G373 PolarHBondContact O-N 2.84Å; A371-G373 VanDerWaalsContact C-N 3.34Å; A371-G373 PolarHBondContact O-N 3.08Å; G373-T376 WeakPolarHBondContact CA-OG1 3.33Å; G373-T376 PolarHBondContact O-N 3.42Å; G373-T376 PolarHBondContact O-OG1 2.83Å; G373-I377 VanDerWaalsContact O-CG1 3.32Å; G373-I377 WeakPolarHBondContact O-CG1 3.26Å; G373-I377 PolarHBondContact O-N 3.09Å; G373-I377 VanDerWaalsContact O-N 3.1Å
374	L	85.5	Confident	83.6	Confident	10 Å²	10	43.1 Å²	43.1	5%	0.052	25%	0.254	C	S	.	.	H	α-helix	trans	-62.5	-45.5	178.4	-176.5	59.4	0	0	0	112.2	I234 L238 F239 F244 S370 A371 V372 I377 V378	I234-L374 HydrophobicContact CG2-CD1 3.94Å; L238-L374 HydrophobicContact CB-CD2 4.26Å; F239-L374 HydrophobicContact CD2-CD2 4.03Å; F239-L374 HydrophobicContact CE1-CD2 4.21Å; F239-L374 HydrophobicContact CE2-CD1 3.7Å; F239-L374 HydrophobicContact CE2-CD2 3.55Å; F239-L374 HydrophobicContact CE2-CG 4.12Å; F239-L374 HydrophobicContact CZ-CD1 3.64Å; F239-L374 HydrophobicContact CZ-CD2 3.66Å; F239-L374 HydrophobicContact CZ-CG 3.91Å; F244-L374 HydrophobicContact CE1-CD2 3.7Å; F244-L374 HydrophobicContact CE1-CG 4.46Å; F244-L374 HydrophobicContact CZ-CB 4.45Å; F244-L374 HydrophobicContact CZ-CD2 3.82Å; F244-L374 HydrophobicContact CZ-CG 4.22Å; S370-L374 PolarHBondContact O-N 3.16Å; A371-L374 PolarHBondContact O-N 3.43Å; V372-L374 PolarHBondContact O-N 2.92Å; L374-I377 PolarHBondContact O-N 3.45Å; L374-V378 WeakPolarHBondContact O-CG2 3.25Å; L374-V378 PolarHBondContact O-N 3.21Å; L374-V378 VanDerWaalsContact O-N 3.13Å
375	T	88.1	Confident	84.5	Confident	2 Å²	2	46 Å²	46	1%	0.012	26%	0.262	C	S	.	.	H	α-helix	trans	-58.9	-48.3	176.2	-68.3	0	0	0	0	111	F244 Y247 L248 A371 V372 I377 V378 E379	F244-T375 WeakPolarHBondContact CE2-OG1 3.29Å; Y247-T375 HydrophobicContact CE1-CG2 4.25Å; L248-T375 HydrophobicContact CD1-CG2 4.32Å; A371-T375 VanDerWaalsContact O-CB 3.25Å; A371-T375 WeakPolarHBondContact O-CB 3.4Å; A371-T375 PolarHBondContact O-N 3.11Å; A371-T375 PolarHBondContact O-OG1 2.9Å; V372-T375 PolarHBondContact O-N 3.1Å; T375-I377 VanDerWaalsContact C-N 3.33Å; T375-I377 PolarHBondContact O-N 3.33Å; T375-V378 PolarHBondContact O-N 3.33Å; T375-E379 HydrophobicContact CG2-CG 4.1Å; T375-E379 WeakPolarHBondContact CG2-OE1 3.4Å; T375-E379 WeakPolarHBondContact O-CB 3.21Å; T375-E379 WeakPolarHBondContact O-CG 3.47Å; T375-E379 PolarHBondContact O-N 3.46Å
376	T	86.8	Confident	85.6	Confident	22 Å²	22	42.5 Å²	42.5	14%	0.135	23%	0.233	C	C	.	.	H	α-helix	trans	-64.1	-33.5	-179.8	53.5	0	0	0	0	114	Y70 V372 G373 C380	Y70-T376 HydrophobicContact CD2-CG2 4.48Å; V372-T376 HydrophobicContact CG1-CG2 4.31Å; V372-T376 WeakPolarHBondContact O-CG2 3.35Å; V372-T376 PolarHBondContact O-N 3.2Å; V372-T376 PolarHBondContact O-OG1 2.99Å; V372-T376 VanDerWaalsContact O-OG1 3.07Å; G373-T376 WeakPolarHBondContact CA-OG1 3.33Å; G373-T376 PolarHBondContact O-N 3.42Å; G373-T376 PolarHBondContact O-OG1 2.83Å; T376-C380 PolarHBondContact O-N 2.94Å
377	I	88.3	Confident	86.8	Confident	55 Å²	55	34.9 Å²	34.9	28%	0.282	20%	0.198	S	C	.	.	H	α-helix	trans	-66.7	-46.1	174.7	-66.7	164.1	0	0	0	109.8	P74 I234 G373 L374 T375 E379 C380	P74-I377 HydrophobicContact CG-CD1 3.6Å; P74-I377 HydrophobicContact CG-CG1 3.67Å; I234-I377 HydrophobicContact CD1-CD1 4.06Å; G373-I377 VanDerWaalsContact O-CG1 3.32Å; G373-I377 WeakPolarHBondContact O-CG1 3.26Å; G373-I377 PolarHBondContact O-N 3.09Å; G373-I377 VanDerWaalsContact O-N 3.1Å; L374-I377 PolarHBondContact O-N 3.45Å; T375-I377 VanDerWaalsContact C-N 3.33Å; T375-I377 PolarHBondContact O-N 3.33Å; I377-E379 VanDerWaalsContact C-N 3.35Å; I377-C380 WeakPolarHBondContact O-CB 3.12Å; I377-C380 PolarHBondContact O-N 3.44Å; I377-C380 PolarHBondContact O-SG 3.17Å
378	V	90.8	Very high	87.8	Confident	44 Å²	44	29 Å²	29	27%	0.267	18%	0.176	S	C	.	.	H	α-helix	trans	-71	-34.3	-178.1	175.9	0	0	0	0	111.3	L248 V252 L374 T375 C380 P382	L248-V378 HydrophobicContact CD1-CB 4.01Å; L248-V378 HydrophobicContact CD1-CG1 4.02Å; L248-V378 HydrophobicContact CD2-CG1 4.33Å; L248-V378 HydrophobicContact CD2-CG2 4.38Å; L248-V378 HydrophobicContact CG-CG1 4.19Å; V252-V378 HydrophobicContact CG2-CG1 3.55Å; L374-V378 WeakPolarHBondContact O-CG2 3.25Å; L374-V378 PolarHBondContact O-N 3.21Å; L374-V378 VanDerWaalsContact O-N 3.13Å; T375-V378 PolarHBondContact O-N 3.33Å; V378-C380 PolarHBondContact O-N 2.68Å; V378-P382 VanDerWaalsContact O-CD 3.26Å; V378-P382 WeakPolarHBondContact O-CD 3.38Å
379	E	90.3	Very high	88.8	Confident	3 Å²	3	31.1 Å²	31.1	1%	0.014	19%	0.189	C	C	.	.	H	α-helix	trans	-67.9	-17.2	175.1	-73.1	174.6	177.6	0	0	113.3	Y70 N251 F255 T375 I377 C381 P382 V383	Y70-E379 HydrophobicContact CD2-CB 4.47Å; N251-E379 PolarHBondContact ND2-OE1 2.94Å; F255-E379 HydrophobicContact CD2-CB 4.28Å; F255-E379 HydrophobicContact CD2-CG 3.66Å; F255-E379 HydrophobicContact CE2-CG 3.84Å; F255-E379 WeakPolarHBondContact CE2-OE1 3.38Å; T375-E379 HydrophobicContact CG2-CG 4.1Å; T375-E379 WeakPolarHBondContact CG2-OE1 3.4Å; T375-E379 WeakPolarHBondContact O-CB 3.21Å; T375-E379 WeakPolarHBondContact O-CG 3.47Å; T375-E379 PolarHBondContact O-N 3.46Å; I377-E379 VanDerWaalsContact C-N 3.35Å; E379-C381 VanDerWaalsContact C-N 3.31Å; E379-C381 PolarHBondContact O-N 3.42Å; E379-P382 VanDerWaalsContact O-CD 3.23Å; E379-P382 WeakPolarHBondContact O-CD 3.22Å; E379-P382 VanDerWaalsContact O-CG 3.29Å; E379-P382 WeakPolarHBondContact O-CG 3.24Å; E379-V383 WeakPolarHBondContact O-CB 3.41Å; E379-V383 WeakPolarHBondContact O-CG2 3.45Å; E379-V383 PolarHBondContact O-N 2.8Å
380	C	91.4	Very high	89.8	Confident	22 Å²	22	27 Å²	27	15%	0.149	16%	0.161	C	C	.	.	H	α-helix	trans	-65.6	-34.9	179.5	86.6	0	0	0	0	112.4	A71 T376 I377 V378 V383 L384	A71-C380 HydrophobicContact CB-CB 4.29Å; T376-C380 PolarHBondContact O-N 2.94Å; I377-C380 WeakPolarHBondContact O-CB 3.12Å; I377-C380 PolarHBondContact O-N 3.44Å; I377-C380 PolarHBondContact O-SG 3.17Å; V378-C380 PolarHBondContact O-N 2.68Å; C380-V383 PolarHBondContact O-N 3.41Å; C380-L384 VanDerWaalsContact O-CB 3.24Å; C380-L384 WeakPolarHBondContact O-CB 3.46Å; C380-L384 PolarHBondContact O-N 3.28Å
381	C	93.2	Very high	90.5	Very high	73 Å²	73	26 Å²	26	49%	0.493	15%	0.154	S	C	.	.	H	α-helix	trans	-61.6	-55.3	179.5	-65.4	0	0	0	0	113.1	E379 V383 L384 I385	E379-C381 VanDerWaalsContact C-N 3.31Å; E379-C381 PolarHBondContact O-N 3.42Å; C381-V383 VanDerWaalsContact C-N 3.33Å; C381-V383 PolarHBondContact O-N 3.48Å; C381-L384 PolarHBondContact O-N 3.29Å; C381-I385 WeakPolarHBondContact O-CG1 3.27Å; C381-I385 PolarHBondContact O-N 3.05Å; C381-I385 VanDerWaalsContact O-N 3.15Å
382	P	94.6	Very high	91	Very high	8 Å²	8	31.6 Å²	31.6	5%	0.052	18%	0.178	C	C	.	.	H	α-helix	trans	-66.2	-34.5	177.9	25.2	-34.5	0	0	0	112.5	V252 F255 L256 V378 E379 L384 I385 G386	V252-P382 HydrophobicContact CG1-CG 4.19Å; V252-P382 WeakPolarHBondContact O-CB 3.41Å; F255-P382 HydrophobicContact CB-CB 4.14Å; F255-P382 HydrophobicContact CB-CG 3.96Å; L256-P382 HydrophobicContact CB-CB 4.19Å; V378-P382 VanDerWaalsContact O-CD 3.26Å; V378-P382 WeakPolarHBondContact O-CD 3.38Å; E379-P382 VanDerWaalsContact O-CD 3.23Å; E379-P382 WeakPolarHBondContact O-CD 3.22Å; E379-P382 VanDerWaalsContact O-CG 3.29Å; E379-P382 WeakPolarHBondContact O-CG 3.24Å; P382-L384 VanDerWaalsContact C-N 3.33Å; P382-L384 PolarHBondContact O-N 3.47Å; P382-I385 PolarHBondContact O-N 3.48Å; P382-G386 WeakPolarHBondContact O-CA 3.41Å; P382-G386 PolarHBondContact O-N 3.26Å
383	V	93.2	Very high	91.5	Very high	1 Å²	1	32.6 Å²	32.6	1%	0.006	18%	0.182	C	C	.	.	H	α-helix	trans	-64.8	-37.6	175.9	170.6	0	0	0	0	111.9	L66 F255 F259 E379 C380 C381 P387	L66-V383 HydrophobicContact CB-CG1 3.8Å; L66-V383 HydrophobicContact CD2-CG1 3.69Å; L66-V383 HydrophobicContact CG-CG1 3.95Å; F255-V383 HydrophobicContact CB-CG2 4.2Å; F255-V383 HydrophobicContact CD1-CG2 4.16Å; F255-V383 HydrophobicContact CG-CG2 4.36Å; F259-V383 HydrophobicContact CD2-CG1 4.4Å; F259-V383 HydrophobicContact CD2-CG2 3.83Å; F259-V383 HydrophobicContact CE2-CG2 3.73Å; E379-V383 WeakPolarHBondContact O-CB 3.41Å; E379-V383 WeakPolarHBondContact O-CG2 3.45Å; E379-V383 PolarHBondContact O-N 2.8Å; C380-V383 PolarHBondContact O-N 3.41Å; C381-V383 VanDerWaalsContact C-N 3.33Å; C381-V383 PolarHBondContact O-N 3.48Å; V383-P387 VanDerWaalsContact O-CD 3.25Å; V383-P387 WeakPolarHBondContact O-CD 3.25Å
384	L	95	Very high	92	Very high	55 Å²	55	31.6 Å²	31.6	29%	0.288	17%	0.172	S	C	.	.	H	α-helix	trans	-68.4	-40.7	177.8	-177.2	60.6	0	0	0	112.2	W60 S63 I64 A67 C380 C381 P382 P388	W60-L384 HydrophobicContact CE3-CD1 4.02Å; W60-L384 HydrophobicContact CZ3-CD1 3.67Å; W60-L384 HydrophobicContact CZ3-CD2 4.43Å; W60-L384 HydrophobicContact CZ3-CG 3.76Å; S63-L384 WeakPolarHBondContact CB-O 3.29Å; I64-L384 HydrophobicContact CB-CD1 4.37Å; I64-L384 HydrophobicContact CG1-CD1 3.74Å; A67-L384 HydrophobicContact CB-CB 3.75Å; A67-L384 HydrophobicContact CB-CD1 3.92Å; A67-L384 HydrophobicContact CB-CG 4.32Å; C380-L384 VanDerWaalsContact O-CB 3.24Å; C380-L384 WeakPolarHBondContact O-CB 3.46Å; C380-L384 PolarHBondContact O-N 3.28Å; C381-L384 PolarHBondContact O-N 3.29Å; P382-L384 VanDerWaalsContact C-N 3.33Å; P382-L384 PolarHBondContact O-N 3.47Å; L384-P388 VanDerWaalsContact O-CD 3.31Å; L384-P388 WeakPolarHBondContact O-CD 3.37Å; L384-P388 WeakPolarHBondContact O-CG 3.34Å
385	I	94.8	Very high	92.2	Very high	89 Å²	89	32.3 Å²	32.3	46%	0.456	18%	0.176	S	C	.	.	H	α-helix	trans	-90.1	-29.5	-172.5	-62.1	169.5	0	0	0	112.3	C381 P382 P388 L389	C381-I385 WeakPolarHBondContact O-CG1 3.27Å; C381-I385 PolarHBondContact O-N 3.05Å; C381-I385 VanDerWaalsContact O-N 3.15Å; P382-I385 PolarHBondContact O-N 3.48Å; I385-P388 WeakPolarHBondContact O-CD 3.3Å; I385-L389 HydrophobicContact CG2-CB 4.39Å; I385-L389 WeakPolarHBondContact O-CB 3.39Å; I385-L389 PolarHBondContact O-N 3.31Å
386	G	94.1	Very high	92.5	Very high	1 Å²	1	38.1 Å²	38.1	1%	0.01	21%	0.206	C	C	.	.	H	α-helix	trans	-56.5	-63	-171.6	0	0	0	0	0	113.7	L256 S260 P382 L389 A390	L256-G386 VanDerWaalsContact O-CA 3.27Å; L256-G386 WeakPolarHBondContact O-CA 3.32Å; S260-G386 VanDerWaalsContact OG-C 3.28Å; S260-G386 PolarHBondContact OG-O 3.01Å; P382-G386 WeakPolarHBondContact O-CA 3.41Å; P382-G386 PolarHBondContact O-N 3.26Å; G386-L389 PolarHBondContact O-N 3.44Å; G386-A390 WeakPolarHBondContact O-CB 3.48Å; G386-A390 PolarHBondContact O-N 2.83Å
387	P	94	Very high	92.6	Very high	3 Å²	3	39.4 Å²	39.4	2%	0.019	21%	0.213	C	C	.	.	H	α-helix	trans	-64.5	-38.9	-178.4	-19.5	30.8	0	0	0	114.4	A59 S63 F259 S260 F264 V383 L389 A390 G391	A59-P387 HydrophobicContact CB-CB 4.1Å; S63-P387 VanDerWaalsContact OG-CB 3.26Å; S63-P387 WeakPolarHBondContact OG-CB 3.28Å; S63-P387 VanDerWaalsContact OG-CG 3.24Å; S63-P387 WeakPolarHBondContact OG-CG 3Å; F259-P387 HydrophobicContact CB-CG 4.49Å; S260-P387 WeakPolarHBondContact OG-CA 3.5Å; F264-P387 HydrophobicContact CE2-CB 4.45Å; F264-P387 WeakPolarHBondContact CE2-O 3.44Å; V383-P387 VanDerWaalsContact O-CD 3.25Å; V383-P387 WeakPolarHBondContact O-CD 3.25Å; P387-L389 PolarHBondContact O-N 3.15Å; P387-A390 PolarHBondContact O-N 3.32Å; P387-G391 PolarHBondContact O-N 2.91Å
388	P	94.6	Very high	92.5	Very high	4 Å²	4	44.2 Å²	44.2	3%	0.026	23%	0.232	C	C	.	.	H	α-helix	trans	-66.2	-36.1	175.5	-25.4	36.6	0	0	0	113.8	S56 A59 W60 S63 L384 I385 G391 K392	S56-P388 WeakPolarHBondContact CB-O 3.25Å; S56-P388 PolarHBondContact OG-O 3.48Å; A59-P388 HydrophobicContact CB-CG 4.45Å; W60-P388 HydrophobicContact CB-CG 4.46Å; W60-P388 HydrophobicContact CD2-CB 3.87Å; W60-P388 HydrophobicContact CD2-CG 3.52Å; W60-P388 VanDerWaalsContact CE2-CB 3.47Å; W60-P388 HydrophobicContact CE3-CG 3.93Å; W60-P388 HydrophobicContact CG-CB 4.06Å; W60-P388 HydrophobicContact CG-CG 3.77Å; W60-P388 HydrophobicContact CZ2-CB 3.91Å; W60-P388 HydrophobicContact CZ2-CG 4.16Å; W60-P388 HydrophobicContact CZ3-CG 4.42Å; S63-P388 WeakPolarHBondContact OG-CD 3.43Å; L384-P388 VanDerWaalsContact O-CD 3.31Å; L384-P388 WeakPolarHBondContact O-CD 3.37Å; L384-P388 WeakPolarHBondContact O-CG 3.34Å; I385-P388 WeakPolarHBondContact O-CD 3.3Å; P388-G391 PolarHBondContact O-N 3.05Å; P388-K392 WeakPolarHBondContact O-CB 3.46Å; P388-K392 PolarHBondContact O-N 3.24Å
389	L	94.3	Very high	92.4	Very high	92 Å²	92	44.9 Å²	44.9	48%	0.482	23%	0.234	S	C	.	.	H	α-helix	trans	-67.3	-42.7	174.4	-175.6	66.1	0	0	0	111	L256 I385 G386 P387 K392 L393	L256-L389 HydrophobicContact CD2-CD2 4.42Å; I385-L389 HydrophobicContact CG2-CB 4.39Å; I385-L389 WeakPolarHBondContact O-CB 3.39Å; I385-L389 PolarHBondContact O-N 3.31Å; G386-L389 PolarHBondContact O-N 3.44Å; P387-L389 PolarHBondContact O-N 3.15Å; L389-K392 PolarHBondContact O-N 3.16Å; L389-L393 PolarHBondContact O-N 3.15Å; L389-L393 VanDerWaalsContact O-N 3.07Å
390	A	93.3	Very high	92.3	Very high	10 Å²	10	44.9 Å²	44.9	8%	0.083	23%	0.234	C	C	.	.	H	α-helix	trans	-62.4	-43.4	174.1	0	0	0	0	0	111.7	F264 G386 P387 K392 L393 V394 M403	F264-A390 HydrophobicContact CE2-CB 4.18Å; G386-A390 WeakPolarHBondContact O-CB 3.48Å; G386-A390 PolarHBondContact O-N 2.83Å; P387-A390 PolarHBondContact O-N 3.32Å; A390-K392 PolarHBondContact O-N 3.3Å; A390-L393 WeakPolarHBondContact O-CB 3.33Å; A390-L393 PolarHBondContact O-N 3.42Å; A390-V394 PolarHBondContact O-N 3.21Å; A390-V394 VanDerWaalsContact O-N 3.14Å; A390-M403 HydrophobicContact CB-CG 3.8Å; A390-M403 HydrophobicContact CB-SD 4.28Å
391	G	92.1	Very high	92.3	Very high	0 Å²	0	46.7 Å²	46.7	0%	0	24%	0.239	C	C	.	.	H	α-helix	trans	-62.3	-40.1	174.6	0	0	0	0	0	112.6	F264 P387 P388 L393 V394 D395	F264-G391 VanDerWaalsContact CZ-CA 3.47Å; P387-G391 PolarHBondContact O-N 2.91Å; P388-G391 PolarHBondContact O-N 3.05Å; G391-L393 VanDerWaalsContact C-N 3.27Å; G391-L393 PolarHBondContact O-N 3.47Å; G391-V394 CarbonylContact O-C 3.59Å; G391-V394 WeakPolarHBondContact O-CB 3.48Å; G391-V394 PolarHBondContact O-N 3.36Å; G391-V394 VanDerWaalsContact O-N 3.13Å; G391-D395 PolarHBondContact O-N 3.19Å
392	K	93.5	Very high	92.2	Very high	118 Å²	118	49.5 Å²	49.5	51%	0.513	24%	0.241	S	C	.	.	H	α-helix	trans	-62.3	-36.3	174.8	-174.3	178.2	179.5	-179.5	0	111.8	P388 L389 A390 V394 D395 I396	P388-K392 WeakPolarHBondContact O-CB 3.46Å; P388-K392 PolarHBondContact O-N 3.24Å; L389-K392 PolarHBondContact O-N 3.16Å; A390-K392 PolarHBondContact O-N 3.3Å; K392-V394 VanDerWaalsContact C-N 3.34Å; K392-D395 WeakPolarHBondContact O-CB 3.35Å; K392-D395 PolarHBondContact O-N 2.59Å; K392-I396 HydrophobicContact CG-CD1 4.16Å; K392-I396 WeakPolarHBondContact O-CG1 3.5Å; K392-I396 PolarHBondContact O-N 2.92Å; K392-I396 VanDerWaalsContact O-N 3.12Å
393	L	93.1	Very high	92.1	Very high	52 Å²	52	49.1 Å²	49.1	27%	0.272	24%	0.238	S	C	.	.	H	α-helix	trans	-64.4	-40.7	174.8	-173.5	63	0	0	0	111.3	L389 A390 G391 I396 T397 C406	L389-L393 PolarHBondContact O-N 3.15Å; L389-L393 VanDerWaalsContact O-N 3.07Å; A390-L393 WeakPolarHBondContact O-CB 3.33Å; A390-L393 PolarHBondContact O-N 3.42Å; G391-L393 VanDerWaalsContact C-N 3.27Å; G391-L393 PolarHBondContact O-N 3.47Å; L393-I396 PolarHBondContact O-N 3.11Å; L393-T397 HydrophobicContact CD1-CG2 4.08Å; L393-T397 HydrophobicContact CG-CG2 4.5Å; L393-T397 WeakPolarHBondContact O-CB 3.3Å; L393-T397 WeakPolarHBondContact O-CG2 3.37Å; L393-T397 PolarHBondContact O-N 3.32Å; L393-T397 PolarHBondContact O-OG1 3.45Å; L393-C406 HydrophobicContact CD2-CB 3.84Å
394	V	91.1	Very high	92.2	Very high	0 Å²	0	49 Å²	49	0%	0	24%	0.238	C	C	.	.	H	α-helix	trans	-65.5	-39.5	172.6	-176.4	0	0	0	0	111.2	Y55 A390 G391 K392 I396 K398 Y400 M403	Y55-V394 HydrophobicContact CD2-CB 4.21Å; Y55-V394 HydrophobicContact CD2-CG1 3.67Å; Y55-V394 HydrophobicContact CE2-CG1 3.88Å; Y55-V394 HydrophobicContact CG-CG1 4.24Å; A390-V394 PolarHBondContact O-N 3.21Å; A390-V394 VanDerWaalsContact O-N 3.14Å; G391-V394 CarbonylContact O-C 3.59Å; G391-V394 WeakPolarHBondContact O-CB 3.48Å; G391-V394 PolarHBondContact O-N 3.36Å; G391-V394 VanDerWaalsContact O-N 3.13Å; K392-V394 VanDerWaalsContact C-N 3.34Å; V394-I396 VanDerWaalsContact C-N 3.3Å; V394-I396 PolarHBondContact O-N 3.4Å; V394-K398 WeakPolarHBondContact O-CA 3.44Å; V394-K398 PolarHBondContact O-N 3.02Å; V394-Y400 HydrophobicContact CG1-CD1 3.96Å; V394-Y400 HydrophobicContact CG1-CD2 4.31Å; V394-Y400 HydrophobicContact CG1-CE1 3.88Å; V394-Y400 HydrophobicContact CG1-CE2 4.23Å; V394-Y400 HydrophobicContact CG1-CG 4.19Å; V394-Y400 HydrophobicContact CG2-CD1 3.87Å; V394-Y400 HydrophobicContact CG2-CE1 4.21Å; V394-Y400 HydrophobicContact CG2-CG 4.49Å; V394-M403 HydrophobicContact CG2-CB 3.53Å; V394-M403 HydrophobicContact CG2-CG 3.84Å; V394-M403 HydrophobicContact CG2-SD 3.81Å
395	D	91	Very high	92.2	Very high	25 Å²	25	50.3 Å²	50.3	13%	0.134	24%	0.241	C	C	.	.	H	α-helix	trans	-59.5	-39.8	178.7	-74.2	-38.3	0	0	0	112.7	S54 Y55 S56 G391 K392 K398	S54-D395 WeakPolarHBondContact CB-OD2 3.42Å; S54-D395 PolarHBondContact OG-OD2 3.28Å; Y55-D395 WeakPolarHBondContact CB-OD1 3.4Å; Y55-D395 WeakPolarHBondContact CD2-OD1 3.34Å; Y55-D395 PolarHBondContact N-OD1 3.27Å; Y55-D395 PolarHBondContact N-OD2 3.3Å; S56-D395 WeakPolarHBondContact CB-OD2 3.07Å; S56-D395 PolarHBondContact N-OD2 3.35Å; G391-D395 PolarHBondContact O-N 3.19Å; K392-D395 WeakPolarHBondContact O-CB 3.35Å; K392-D395 PolarHBondContact O-N 2.59Å; D395-K398 WeakPolarHBondContact O-CD 3.4Å; D395-K398 WeakPolarHBondContact O-CE 3.29Å; D395-K398 PolarHBondContact O-NZ 3.02Å; D395-K398 VanDerWaalsContact O-NZ 3.12Å
396	I	92.3	Very high	92.2	Very high	124 Å²	124	49.2 Å²	49.2	64%	0.636	24%	0.241	S	C	*	.	H	α-helix	trans	-79.2	-48.7	-179.4	-64.2	166.2	0	0	0	111.3	K392 L393 V394 K398	K392-I396 HydrophobicContact CG-CD1 4.16Å; K392-I396 WeakPolarHBondContact O-CG1 3.5Å; K392-I396 PolarHBondContact O-N 2.92Å; K392-I396 VanDerWaalsContact O-N 3.12Å; L393-I396 PolarHBondContact O-N 3.11Å; V394-I396 VanDerWaalsContact C-N 3.3Å; V394-I396 PolarHBondContact O-N 3.4Å; I396-K398 VanDerWaalsContact C-N 3.35Å
397	T	90.4	Very high	92.2	Very high	49 Å²	49	49.6 Å²	49.6	30%	0.301	24%	0.243	S	C	.	.	H	α-helix	trans	-81.2	-17.3	-174.8	59.6	0	0	0	0	113.2	L393 N399 Y402	L393-T397 HydrophobicContact CD1-CG2 4.08Å; L393-T397 HydrophobicContact CG-CG2 4.5Å; L393-T397 WeakPolarHBondContact O-CB 3.3Å; L393-T397 WeakPolarHBondContact O-CG2 3.37Å; L393-T397 PolarHBondContact O-N 3.32Å; L393-T397 PolarHBondContact O-OG1 3.45Å; T397-N399 PolarHBondContact O-N 2.97Å; T397-N399 VanDerWaalsContact O-N 3.11Å; T397-N399 PolarHBondContact OG1-N 2.92Å; T397-N399 PolarHBondContact OG1-O 3.04Å; T397-Y402 HydrophobicContact CG2-CD2 4.09Å; T397-Y402 HydrophobicContact CG2-CG 4.41Å
398	K	85.8	Confident	92.3	Very high	156 Å²	156	49.5 Å²	49.5	68%	0.678	24%	0.242	S	C	*	.	S	Bend	trans	54.6	20.1	-171.3	-57.6	-61.2	-174.1	-168.8	0	113.9	V394 D395 I396	V394-K398 WeakPolarHBondContact O-CA 3.44Å; V394-K398 PolarHBondContact O-N 3.02Å; D395-K398 WeakPolarHBondContact O-CD 3.4Å; D395-K398 WeakPolarHBondContact O-CE 3.29Å; D395-K398 PolarHBondContact O-NZ 3.02Å; D395-K398 VanDerWaalsContact O-NZ 3.12Å; I396-K398 VanDerWaalsContact C-N 3.35Å
399	N	87.9	Confident	92.3	Very high	58 Å²	58	51.2 Å²	51.2	31%	0.31	26%	0.257	S	S	.	.			trans	-142.4	119.8	-176	-166.7	-27.6	0	0	0	111.5	T397 K401 Y402	T397-N399 PolarHBondContact O-N 2.97Å; T397-N399 VanDerWaalsContact O-N 3.11Å; T397-N399 PolarHBondContact OG1-N 2.92Å; T397-N399 PolarHBondContact OG1-O 3.04Å; N399-K401 PolarHBondContact O-N 3.21Å; N399-K401 VanDerWaalsContact OD1-CB 3.26Å; N399-K401 WeakPolarHBondContact OD1-CB 3.37Å; N399-K401 VanDerWaalsContact OD1-CG 3.26Å; N399-K401 WeakPolarHBondContact OD1-CG 3.38Å; N399-K401 PolarHBondContact OD1-N 3.32Å; N399-Y402 HydrophobicContact CB-CD2 3.96Å; N399-Y402 HydrophobicContact CB-CE2 4.15Å
400	Y	89	Confident	92.4	Very high	2 Å²	2	48.2 Å²	48.2	1%	0.008	24%	0.243	C	C	.	.	H	α-helix	trans	-63.2	-23.3	178.5	-71.5	-84.1	0	0	0	113.6	Y55 F264 A267 Y268 D271 V394 Y402 M403 Y404	Y55-Y400 WeakPolarHBondContact CD1-OH 3.46Å; Y55-Y400 AromaticContact CE1-CZ 3.9Å; Y55-Y400 WeakPolarHBondContact CE1-OH 3.23Å; Y55-Y400 PolarHBondContact OH-OH 3.22Å; F264-Y400 HydrophobicContact CB-CE1 4.29Å; F264-Y400 HydrophobicContact CD1-CE1 4.21Å; F264-Y400 HydrophobicContact CG-CE1 4.5Å; A267-Y400 HydrophobicContact CB-CE1 4.45Å; Y268-Y400 HydrophobicContact CD2-CD1 4.47Å; Y268-Y400 AromaticContact CD2-CD2 3.83Å; Y268-Y400 HydrophobicContact CD2-CD2 3.83Å; Y268-Y400 AromaticContact CD2-CG 3.64Å; Y268-Y400 HydrophobicContact CD2-CG 3.64Å; Y268-Y400 HydrophobicContact CE2-CG 4.44Å; Y268-Y400 HydrophobicContact CG-CG 4.31Å; D271-Y400 HydrophobicContact CB-CD2 4.11Å; D271-Y400 HydrophobicContact CB-CE2 3.72Å; D271-Y400 WeakPolarHBondContact OD2-CD2 3.34Å; V394-Y400 HydrophobicContact CG1-CD1 3.96Å; V394-Y400 HydrophobicContact CG1-CD2 4.31Å; V394-Y400 HydrophobicContact CG1-CE1 3.88Å; V394-Y400 HydrophobicContact CG1-CE2 4.23Å; V394-Y400 HydrophobicContact CG1-CG 4.19Å; V394-Y400 HydrophobicContact CG2-CD1 3.87Å; V394-Y400 HydrophobicContact CG2-CE1 4.21Å; V394-Y400 HydrophobicContact CG2-CG 4.49Å; Y400-Y402 VanDerWaalsContact C-N 3.31Å; Y400-Y402 PolarHBondContact O-N 3.4Å; Y400-M403 HydrophobicContact CD1-SD 4.4Å; Y400-M403 WeakPolarHBondContact O-CB 3.45Å; Y400-M403 PolarHBondContact O-N 3.46Å; Y400-M403 VanDerWaalsContact O-N 3.09Å; Y400-Y404 WeakPolarHBondContact O-CD2 3.28Å; Y400-Y404 PolarHBondContact O-N 3.28Å; Y400-Y404 VanDerWaalsContact O-N 3.11Å
401	K	90.4	Very high	92.6	Very high	60 Å²	60	47.8 Å²	47.8	26%	0.261	24%	0.239	S	C	.	.	H	α-helix	trans	-56.2	-44.6	-179.4	-67.8	-173.7	178.1	-173.5	0	111.6	P329 E332 N399 M403 Y404 F405	P329-K401 HydrophobicContact CB-CB 3.88Å; P329-K401 HydrophobicContact CB-CD 4.34Å; P329-K401 HydrophobicContact CB-CG 3.85Å; P329-K401 HydrophobicContact CG-CB 4.34Å; P329-K401 WeakPolarHBondContact CG-O 3.44Å; P329-K401 WeakPolarHBondContact O-CE 3.19Å; E332-K401 IonicContact OE1-NZ 3.08Å; E332-K401 PolarHBondContact OE1-NZ 3.18Å; N399-K401 PolarHBondContact O-N 3.21Å; N399-K401 VanDerWaalsContact OD1-CB 3.26Å; N399-K401 WeakPolarHBondContact OD1-CB 3.37Å; N399-K401 VanDerWaalsContact OD1-CG 3.26Å; N399-K401 WeakPolarHBondContact OD1-CG 3.38Å; N399-K401 PolarHBondContact OD1-N 3.32Å; K401-M403 VanDerWaalsContact C-N 3.34Å; K401-M403 PolarHBondContact O-N 3.12Å; K401-Y404 PolarHBondContact O-N 3.29Å; K401-F405 HydrophobicContact CB-CE2 4.5Å; K401-F405 WeakPolarHBondContact O-CD2 3.38Å; K401-F405 PolarHBondContact O-N 3.45Å
402	Y	91.6	Very high	92.8	Very high	132 Å²	132	49.3 Å²	49.3	52%	0.518	25%	0.247	S	C	.	.	H	α-helix	trans	-66	-35.2	178	-63.2	-69.5	0	0	0	112.9	T397 N399 Y400 F405 C406	T397-Y402 HydrophobicContact CG2-CD2 4.09Å; T397-Y402 HydrophobicContact CG2-CG 4.41Å; N399-Y402 HydrophobicContact CB-CD2 3.96Å; N399-Y402 HydrophobicContact CB-CE2 4.15Å; Y400-Y402 VanDerWaalsContact C-N 3.31Å; Y400-Y402 PolarHBondContact O-N 3.4Å; Y402-F405 PolarHBondContact O-N 3.12Å; Y402-C406 WeakPolarHBondContact O-CB 3.4Å; Y402-C406 PolarHBondContact O-N 2.87Å
403	M	93.8	Very high	93	Very high	0 Å²	0	49 Å²	49	0%	0	25%	0.249	C	C	.	.	H	α-helix	trans	-61.7	-47.5	175.4	-178	-146.3	70.2	0	0	111.4	F264 A390 V394 Y400 K401 C406 C407	F264-M403 HydrophobicContact CB-CE 4.05Å; F264-M403 HydrophobicContact CB-SD 3.93Å; F264-M403 HydrophobicContact CD2-CE 4.4Å; F264-M403 HydrophobicContact CD2-SD 3.4Å; F264-M403 WeakPolarHBondContact CD2-SD 3.44Å; F264-M403 HydrophobicContact CE2-SD 4.06Å; F264-M403 HydrophobicContact CG-SD 3.82Å; A390-M403 HydrophobicContact CB-CG 3.8Å; A390-M403 HydrophobicContact CB-SD 4.28Å; V394-M403 HydrophobicContact CG2-CB 3.53Å; V394-M403 HydrophobicContact CG2-CG 3.84Å; V394-M403 HydrophobicContact CG2-SD 3.81Å; Y400-M403 HydrophobicContact CD1-SD 4.4Å; Y400-M403 WeakPolarHBondContact O-CB 3.45Å; Y400-M403 PolarHBondContact O-N 3.46Å; Y400-M403 VanDerWaalsContact O-N 3.09Å; K401-M403 VanDerWaalsContact C-N 3.34Å; K401-M403 PolarHBondContact O-N 3.12Å; M403-C406 PolarHBondContact O-N 3.08Å; M403-C407 WeakPolarHBondContact O-CB 3.33Å; M403-C407 PolarHBondContact O-N 3Å; M403-C407 PolarHBondContact O-SG 3.2Å
404	Y	94.1	Very high	93.1	Very high	0 Å²	0	46.6 Å²	46.6	0%	0	24%	0.236	C	C	.	.	H	α-helix	trans	-64.8	-40.4	176.9	-81.9	-79	0	0	0	112.4	P261 Y268 C328 Y400 K401 C407 G408	P261-Y404 HydrophobicContact CB-CD1 4.1Å; P261-Y404 HydrophobicContact CB-CE1 3.67Å; P261-Y404 HydrophobicContact CG-CD1 4.42Å; P261-Y404 HydrophobicContact CG-CE1 4.44Å; P261-Y404 PolarHBondContact O-OH 3.4Å; Y268-Y404 AromaticContact CD1-CE2 3.71Å; Y268-Y404 HydrophobicContact CD1-CE2 3.71Å; Y268-Y404 HydrophobicContact CD2-CE2 4.45Å; Y268-Y404 HydrophobicContact CE1-CE2 4.11Å; Y268-Y404 AromaticContact CG-CE2 3.87Å; Y268-Y404 HydrophobicContact CG-CE2 3.87Å; C328-Y404 HydrophobicContact CB-CD1 3.92Å; C328-Y404 HydrophobicContact CB-CE1 4.25Å; C328-Y404 HydrophobicContact CB-CG 4.25Å; Y400-Y404 WeakPolarHBondContact O-CD2 3.28Å; Y400-Y404 PolarHBondContact O-N 3.28Å; Y400-Y404 VanDerWaalsContact O-N 3.11Å; K401-Y404 PolarHBondContact O-N 3.29Å; Y404-C407 PolarHBondContact O-N 3.4Å; Y404-G408 PolarHBondContact O-N 3.02Å
405	F	94.5	Very high	93.3	Very high	81 Å²	81	46.8 Å²	46.8	36%	0.355	24%	0.237	S	C	.	.	H	α-helix	trans	-60.8	-47.2	174.2	-76.7	-54.4	0	0	0	112.3	I326 P329 K401 Y402 G408 A409	I326-F405 HydrophobicContact CG2-CD1 4.01Å; I326-F405 HydrophobicContact CG2-CE1 3.94Å; I326-F405 WeakPolarHBondContact O-CE1 3.48Å; P329-F405 HydrophobicContact CB-CD2 4.36Å; P329-F405 HydrophobicContact CB-CE1 4.35Å; P329-F405 HydrophobicContact CB-CE2 3.7Å; P329-F405 HydrophobicContact CB-CZ 3.69Å; P329-F405 HydrophobicContact CG-CD1 4.33Å; P329-F405 HydrophobicContact CG-CD2 4.08Å; P329-F405 HydrophobicContact CG-CE1 4.14Å; P329-F405 HydrophobicContact CG-CE2 3.89Å; P329-F405 HydrophobicContact CG-CG 4.29Å; P329-F405 HydrophobicContact CG-CZ 3.92Å; K401-F405 HydrophobicContact CB-CE2 4.5Å; K401-F405 WeakPolarHBondContact O-CD2 3.38Å; K401-F405 PolarHBondContact O-N 3.45Å; Y402-F405 PolarHBondContact O-N 3.12Å; F405-G408 PolarHBondContact O-N 3.5Å; F405-A409 VanDerWaalsContact O-CB 3.31Å; F405-A409 WeakPolarHBondContact O-CB 3.4Å; F405-A409 PolarHBondContact O-N 3.46Å
406	C	94.7	Very high	93.5	Very high	67 Å²	67	49.8 Å²	49.8	45%	0.453	25%	0.252	S	S	.	.	H	α-helix	trans	-64.3	-44.5	177.4	-79.7	0	0	0	0	112.2	L393 Y402 M403 A409 V410	L393-C406 HydrophobicContact CD2-CB 3.84Å; Y402-C406 WeakPolarHBondContact O-CB 3.4Å; Y402-C406 PolarHBondContact O-N 2.87Å; M403-C406 PolarHBondContact O-N 3.08Å; C406-A409 PolarHBondContact O-N 2.86Å; C406-V410 WeakPolarHBondContact O-CG2 3.37Å; C406-V410 PolarHBondContact O-N 3.5Å
407	C	94.7	Very high	93.7	Very high	9 Å²	9	50.2 Å²	50.2	6%	0.061	25%	0.246	C	C	.	.	H	α-helix	trans	-61.8	-46	177.2	-65.4	0	0	0	0	111.1	P261 M403 Y404 A409 V410 V411	P261-C407 HydrophobicContact CG-CB 3.8Å; M403-C407 WeakPolarHBondContact O-CB 3.33Å; M403-C407 PolarHBondContact O-N 3Å; M403-C407 PolarHBondContact O-SG 3.2Å; Y404-C407 PolarHBondContact O-N 3.4Å; C407-A409 PolarHBondContact O-N 3.37Å; C407-V410 PolarHBondContact O-N 3.3Å; C407-V411 WeakPolarHBondContact O-CG2 3.37Å; C407-V411 PolarHBondContact O-N 3.31Å
408	G	95.4	Very high	93.8	Very high	0 Å²	0	47.9 Å²	47.9	0%	0	23%	0.232	C	C	.	.	H	α-helix	trans	-61.5	-43.4	176.8	0	0	0	0	0	112.6	Y404 F405 V410 V411 I412	Y404-G408 PolarHBondContact O-N 3.02Å; F405-G408 PolarHBondContact O-N 3.5Å; G408-V410 PolarHBondContact O-N 3.47Å; G408-V411 PolarHBondContact O-N 2.88Å; G408-I412 VanDerWaalsContact O-CG1 3.3Å; G408-I412 WeakPolarHBondContact O-CG1 3.37Å; G408-I412 PolarHBondContact O-N 2.9Å
409	A	96.3	Very high	94.1	Very high	41 Å²	41	45.6 Å²	45.6	34%	0.339	22%	0.222	S	C	.	.	H	α-helix	trans	-61.1	-43.7	175.8	0	0	0	0	0	112.2	F405 C406 C407 V411 I412 M413	F405-A409 VanDerWaalsContact O-CB 3.31Å; F405-A409 WeakPolarHBondContact O-CB 3.4Å; F405-A409 PolarHBondContact O-N 3.46Å; C406-A409 PolarHBondContact O-N 2.86Å; C407-A409 PolarHBondContact O-N 3.37Å; A409-V411 PolarHBondContact O-N 3.35Å; A409-I412 PolarHBondContact O-N 3.37Å; A409-M413 WeakPolarHBondContact O-CB 3.44Å; A409-M413 VanDerWaalsContact O-CG 3.29Å; A409-M413 WeakPolarHBondContact O-CG 3.44Å; A409-M413 PolarHBondContact O-N 3.27Å
410	V	96.1	Very high	94.3	Very high	29 Å²	29	47.1 Å²	47.1	18%	0.176	23%	0.229	C	C	.	.	H	α-helix	trans	-61.2	-44.4	176.2	170	0	0	0	0	111.6	I253 L256 C406 C407 G408 M413 A414	I253-V410 HydrophobicContact CG2-CG1 4.22Å; I253-V410 VanDerWaalsContact O-CG1 3.22Å; I253-V410 WeakPolarHBondContact O-CG1 3.43Å; L256-V410 HydrophobicContact CB-CG1 4.31Å; L256-V410 HydrophobicContact CD2-CG1 4.41Å; C406-V410 WeakPolarHBondContact O-CG2 3.37Å; C406-V410 PolarHBondContact O-N 3.5Å; C407-V410 PolarHBondContact O-N 3.3Å; G408-V410 PolarHBondContact O-N 3.47Å; V410-M413 HydrophobicContact CB-CE 4.4Å; V410-M413 HydrophobicContact CG2-CE 3.99Å; V410-M413 PolarHBondContact O-N 2.94Å; V410-A414 PolarHBondContact O-N 3.46Å
411	V	96.5	Very high	94.2	Very high	0 Å²	0	47.4 Å²	47.4	0%	0	23%	0.233	C	C	.	.	H	α-helix	trans	-67.1	-39.4	178.8	175.8	0	0	0	0	111.4	V318 C407 G408 A409 A414 S415	V318-V411 HydrophobicContact CG1-CG1 3.71Å; V318-V411 WeakPolarHBondContact O-CG1 3.44Å; C407-V411 WeakPolarHBondContact O-CG2 3.37Å; C407-V411 PolarHBondContact O-N 3.31Å; G408-V411 PolarHBondContact O-N 2.88Å; A409-V411 PolarHBondContact O-N 3.35Å; V411-A414 WeakPolarHBondContact O-CB 3.35Å; V411-A414 PolarHBondContact O-N 3.43Å; V411-S415 PolarHBondContact O-N 2.92Å
412	I	96.9	Very high	94	Very high	33 Å²	33	44.9 Å²	44.9	17%	0.169	22%	0.222	C	C	.	.	H	α-helix	trans	-65.2	-42.6	174.3	-68.7	177.4	0	0	0	111.1	L319 V323 I326 G408 A409 A414 S415 I416	L319-I412 HydrophobicContact CD1-CG1 4.28Å; L319-I412 HydrophobicContact CD1-CG2 4.03Å; V323-I412 HydrophobicContact CG2-CD1 4.15Å; I326-I412 HydrophobicContact CD1-CD1 3.42Å; I326-I412 VanDerWaalsContact CD1-CD1 3.42Å; I326-I412 HydrophobicContact CG1-CD1 4.3Å; G408-I412 VanDerWaalsContact O-CG1 3.3Å; G408-I412 WeakPolarHBondContact O-CG1 3.37Å; G408-I412 PolarHBondContact O-N 2.9Å; A409-I412 PolarHBondContact O-N 3.37Å; I412-A414 VanDerWaalsContact C-N 3.31Å; I412-A414 PolarHBondContact O-N 3.22Å; I412-S415 WeakPolarHBondContact O-CB 3.27Å; I412-S415 PolarHBondContact O-N 3.48Å; I412-S415 VanDerWaalsContact O-N 3.14Å; I412-I416 HydrophobicContact CG2-CD1 3.88Å; I412-I416 HydrophobicContact CG2-CG1 4.4Å; I412-I416 WeakPolarHBondContact O-CG1 3.31Å; I412-I416 PolarHBondContact O-N 3.48Å
413	M	96.8	Very high	93.8	Very high	112 Å²	112	42.7 Å²	42.7	55%	0.552	22%	0.216	S	C	*	.	H	α-helix	trans	-59.3	-42.7	174.4	-74.7	-172.8	-63.1	0	0	111.4	A409 V410 S415 I416 W417	A409-M413 WeakPolarHBondContact O-CB 3.44Å; A409-M413 VanDerWaalsContact O-CG 3.29Å; A409-M413 WeakPolarHBondContact O-CG 3.44Å; A409-M413 PolarHBondContact O-N 3.27Å; V410-M413 HydrophobicContact CB-CE 4.4Å; V410-M413 HydrophobicContact CG2-CE 3.99Å; V410-M413 PolarHBondContact O-N 2.94Å; M413-S415 VanDerWaalsContact C-N 3.32Å; M413-S415 PolarHBondContact O-N 3.03Å; M413-I416 PolarHBondContact O-N 2.94Å; M413-W417 WeakPolarHBondContact O-CB 3.29Å; M413-W417 PolarHBondContact O-N 3.27Å
414	A	95.9	Very high	93.3	Very high	0 Å²	0	46.7 Å²	46.7	0%	0	24%	0.236	C	C	.	.	H	α-helix	trans	-60.7	-41.5	174.5	0	0	0	0	0	112	I253 M254 V410 V411 I412 W417 L418	I253-A414 HydrophobicContact CB-CB 3.98Å; I253-A414 HydrophobicContact CG2-CB 3.79Å; M254-A414 HydrophobicContact CB-CB 3.81Å; V410-A414 PolarHBondContact O-N 3.46Å; V411-A414 WeakPolarHBondContact O-CB 3.35Å; V411-A414 PolarHBondContact O-N 3.43Å; I412-A414 VanDerWaalsContact C-N 3.31Å; I412-A414 PolarHBondContact O-N 3.22Å; A414-W417 PolarHBondContact O-N 3.1Å; A414-L418 WeakPolarHBondContact O-CB 3.42Å; A414-L418 WeakPolarHBondContact O-CG 3.29Å; A414-L418 PolarHBondContact O-N 3.31Å
415	S	95.8	Very high	92.8	Very high	4 Å²	4	47.3 Å²	47.3	3%	0.028	24%	0.24	C	C	.	.	H	α-helix	trans	-62.2	-47.7	175.7	172.1	0	0	0	0	112.4	S315 L319 V411 I412 M413 W417 L418 F419	S315-S415 PolarHBondContact O-OG 3.38Å; L319-S415 VanDerWaalsContact CB-OG 3.32Å; L319-S415 WeakPolarHBondContact CB-OG 3.26Å; L319-S415 PolarHBondContact N-OG 3.39Å; V411-S415 PolarHBondContact O-N 2.92Å; I412-S415 WeakPolarHBondContact O-CB 3.27Å; I412-S415 PolarHBondContact O-N 3.48Å; I412-S415 VanDerWaalsContact O-N 3.14Å; M413-S415 VanDerWaalsContact C-N 3.32Å; M413-S415 PolarHBondContact O-N 3.03Å; S415-W417 VanDerWaalsContact C-N 3.3Å; S415-W417 PolarHBondContact O-N 3.34Å; S415-L418 PolarHBondContact O-N 2.98Å; S415-F419 WeakPolarHBondContact O-CB 3.21Å; S415-F419 PolarHBondContact O-N 3.17Å
416	I	95.5	Very high	92.3	Very high	89 Å²	89	46.2 Å²	46.2	46%	0.456	23%	0.233	S	C	.	.	H	α-helix	trans	-62	-42.7	179	-66.6	168	0	0	0	109.9	I412 M413 F419 I420	I412-I416 HydrophobicContact CG2-CD1 3.88Å; I412-I416 HydrophobicContact CG2-CG1 4.4Å; I412-I416 WeakPolarHBondContact O-CG1 3.31Å; I412-I416 PolarHBondContact O-N 3.48Å; M413-I416 PolarHBondContact O-N 2.94Å; I416-F419 PolarHBondContact O-N 2.96Å; I416-I420 HydrophobicContact CG2-CD1 3.67Å; I416-I420 HydrophobicContact CG2-CG1 4.37Å; I416-I420 WeakPolarHBondContact O-CB 3.38Å; I416-I420 VanDerWaalsContact O-CG1 3.32Å; I416-I420 WeakPolarHBondContact O-CG1 3.38Å; I416-I420 PolarHBondContact O-N 3.47Å
417	W	95.1	Very high	91.7	Very high	132 Å²	132	50.6 Å²	50.6	50%	0.5	24%	0.241	S	C	.	.	H	α-helix	trans	-58.9	-49.8	174.9	178.9	-99.8	0	0	0	112.2	S249 I253 M413 A414 S415 F419 I420 G421	S249-W417 PolarHBondContact OG-NE1 2.93Å; I253-W417 HydrophobicContact CD1-CG 4.41Å; M413-W417 WeakPolarHBondContact O-CB 3.29Å; M413-W417 PolarHBondContact O-N 3.27Å; A414-W417 PolarHBondContact O-N 3.1Å; S415-W417 VanDerWaalsContact C-N 3.3Å; S415-W417 PolarHBondContact O-N 3.34Å; W417-F419 VanDerWaalsContact C-N 3.32Å; W417-F419 PolarHBondContact O-N 3.19Å; W417-I420 PolarHBondContact O-N 2.79Å; W417-G421 PolarHBondContact O-N 3.5Å
418	L	93	Very high	91	Very high	1 Å²	1	53.2 Å²	53.2	1%	0.005	25%	0.254	C	S	.	.	H	α-helix	trans	-61.3	-41.4	177	-75.5	169.6	0	0	0	111.5	F314 S315 A414 S415 N422	F314-L418 HydrophobicContact CD1-CD1 4.03Å; F314-L418 HydrophobicContact CE1-CD1 3.63Å; S315-L418 WeakPolarHBondContact OG-CB 3.41Å; A414-L418 WeakPolarHBondContact O-CB 3.42Å; A414-L418 WeakPolarHBondContact O-CG 3.29Å; A414-L418 PolarHBondContact O-N 3.31Å; S415-L418 PolarHBondContact O-N 2.98Å; L418-N422 WeakPolarHBondContact O-CB 3.42Å; L418-N422 PolarHBondContact O-N 3.4Å; L418-N422 PolarHBondContact O-ND2 2.8Å
419	F	93	Very high	90.3	Very high	108 Å²	108	55.9 Å²	55.9	47%	0.474	27%	0.268	S	S	.	.	H	α-helix	trans	-64.2	-48.2	-179.7	-168	-91.7	0	0	0	111.8	Y312 S315 S415 I416 W417 F423	Y312-F419 AromaticContact CD1-CD2 3.86Å; Y312-F419 HydrophobicContact CD1-CD2 3.86Å; Y312-F419 AromaticContact CD1-CE2 3.62Å; Y312-F419 HydrophobicContact CD1-CE2 3.62Å; Y312-F419 HydrophobicContact CD1-CZ 4.22Å; Y312-F419 HydrophobicContact CE1-CD2 4.45Å; Y312-F419 HydrophobicContact CE1-CE2 4.2Å; Y312-F419 HydrophobicContact CE1-CZ 4.38Å; S315-F419 PolarHBondContact OG-N 3.08Å; S415-F419 WeakPolarHBondContact O-CB 3.21Å; S415-F419 PolarHBondContact O-N 3.17Å; I416-F419 PolarHBondContact O-N 2.96Å; W417-F419 VanDerWaalsContact C-N 3.32Å; W417-F419 PolarHBondContact O-N 3.19Å; F419-F423 WeakPolarHBondContact O-CB 3.46Å; F419-F423 PolarHBondContact O-N 3.26Å
420	I	91.6	Very high	89.6	Confident	89 Å²	89	56.2 Å²	56.2	46%	0.456	27%	0.27	S	S	.	.	H	α-helix	trans	-66.2	-45.4	177.8	-65.8	170.3	0	0	0	110.6	I416 W417 N422 F423 I424	I416-I420 HydrophobicContact CG2-CD1 3.67Å; I416-I420 HydrophobicContact CG2-CG1 4.37Å; I416-I420 WeakPolarHBondContact O-CB 3.38Å; I416-I420 VanDerWaalsContact O-CG1 3.32Å; I416-I420 WeakPolarHBondContact O-CG1 3.38Å; I416-I420 PolarHBondContact O-N 3.47Å; W417-I420 PolarHBondContact O-N 2.79Å; I420-N422 PolarHBondContact O-N 3.35Å; I420-F423 WeakPolarHBondContact O-CB 3.46Å; I420-F423 PolarHBondContact O-N 3.33Å; I420-I424 HydrophobicContact CG2-CD1 3.86Å; I420-I424 HydrophobicContact CG2-CG1 4.46Å; I420-I424 WeakPolarHBondContact O-CG1 3.37Å; I420-I424 PolarHBondContact O-N 3.28Å
421	G	87.1	Confident	88.9	Confident	9 Å²	9	61.4 Å²	61.4	9%	0.093	29%	0.29	C	S	.	.	H	α-helix	trans	-59.7	-47.1	178.8	0	0	0	0	0	111.8	W417 F423 I424 N425	W417-G421 PolarHBondContact O-N 3.5Å; G421-F423 VanDerWaalsContact C-N 3.34Å; G421-F423 PolarHBondContact O-N 2.81Å; G421-I424 PolarHBondContact O-N 3.36Å; G421-N425 WeakPolarHBondContact O-CB 3.48Å; G421-N425 PolarHBondContact O-N 2.95Å
422	N	86.7	Confident	88.3	Confident	7 Å²	7	64.6 Å²	64.6	4%	0.037	31%	0.305	C	S	.	.	H	α-helix	trans	-63.8	-40.6	176.3	-68.2	-25.8	0	0	0	111.1	Q311 Y312 L418 I420 I424 N425 Y426	Q311-N422 HydrophobicContact CB-CB 4.38Å; Q311-N422 PolarHBondContact O-ND2 3.14Å; Q311-N422 PolarHBondContact OE1-OD1 2.64Å; Y312-N422 HydrophobicContact CE1-CB 4.47Å; L418-N422 WeakPolarHBondContact O-CB 3.42Å; L418-N422 PolarHBondContact O-N 3.4Å; L418-N422 PolarHBondContact O-ND2 2.8Å; I420-N422 PolarHBondContact O-N 3.35Å; N422-I424 PolarHBondContact O-N 3Å; N422-N425 PolarHBondContact O-N 3.47Å; N422-Y426 WeakPolarHBondContact O-CD2 3.41Å; N422-Y426 PolarHBondContact O-N 2.97Å
423	F	85.4	Confident	87.6	Confident	85 Å²	85	70.3 Å²	70.3	37%	0.373	33%	0.325	S	S	.	.	H	α-helix	trans	-59.4	-44.8	175.5	-179.3	-100.7	0	0	0	113	Y312 F419 I420 G421 R427	Y312-F423 WeakPolarHBondContact OH-CA 3.28Å; F419-F423 WeakPolarHBondContact O-CB 3.46Å; F419-F423 PolarHBondContact O-N 3.26Å; I420-F423 WeakPolarHBondContact O-CB 3.46Å; I420-F423 PolarHBondContact O-N 3.33Å; G421-F423 VanDerWaalsContact C-N 3.34Å; G421-F423 PolarHBondContact O-N 2.81Å; F423-R427 HydrophobicContact CE1-CG 4.41Å; F423-R427 HydrophobicContact CZ-CG 4.44Å; F423-R427 VanDerWaalsContact CZ-CZ 3.47Å; F423-R427 PolarHBondContact O-N 3.03Å
424	I	84	Confident	86.9	Confident	85 Å²	85	71.8 Å²	71.8	44%	0.436	33%	0.328	S	S	.	.	H	α-helix	trans	-63.2	-44.8	175.4	-66.4	167.2	0	0	0	110.2	I420 G421 N422 Y426 R427 L428	I420-I424 HydrophobicContact CG2-CD1 3.86Å; I420-I424 HydrophobicContact CG2-CG1 4.46Å; I420-I424 WeakPolarHBondContact O-CG1 3.37Å; I420-I424 PolarHBondContact O-N 3.28Å; G421-I424 PolarHBondContact O-N 3.36Å; N422-I424 PolarHBondContact O-N 3Å; I424-Y426 PolarHBondContact O-N 3.32Å; I424-R427 PolarHBondContact O-N 3.43Å; I424-L428 HydrophobicContact CG2-CD1 3.81Å; I424-L428 HydrophobicContact CG2-CG 4.35Å; I424-L428 WeakPolarHBondContact O-CG 3.34Å; I424-L428 PolarHBondContact O-N 3.08Å
425	N	84.5	Confident	86.2	Confident	13 Å²	13	78.2 Å²	78.2	7%	0.07	36%	0.358	C	S	.	.	H	α-helix	trans	-60.4	-46.6	179.4	-169.7	43	0	0	0	111.8	I246 G421 N422 R427 L428 L429	I246-N425 HydrophobicContact CD1-CB 4.07Å; G421-N425 WeakPolarHBondContact O-CB 3.48Å; G421-N425 PolarHBondContact O-N 2.95Å; N422-N425 PolarHBondContact O-N 3.47Å; N425-R427 VanDerWaalsContact C-N 3.34Å; N425-R427 PolarHBondContact O-N 3.08Å; N425-L428 PolarHBondContact O-N 3.34Å; N425-L429 WeakPolarHBondContact O-CB 3.43Å; N425-L429 WeakPolarHBondContact O-CD1 2.82Å; N425-L429 WeakPolarHBondContact O-CG 3.29Å; N425-L429 PolarHBondContact O-N 3.17Å
426	Y	82.9	Confident	85.5	Confident	57 Å²	57	83.7 Å²	83.7	22%	0.224	38%	0.383	C	S	.	.	H	α-helix	trans	-62.6	-38.8	175.9	-82	-67.4	0	0	0	112.7	Q311 Y312 N422 I424 A430	Q311-Y426 HydrophobicContact CB-CE2 4.22Å; Y312-Y426 HydrophobicContact CD2-CD2 4.48Å; Y312-Y426 HydrophobicContact CD2-CE2 4.04Å; Y312-Y426 AromaticContact CE2-CD2 3.48Å; Y312-Y426 HydrophobicContact CE2-CD2 3.48Å; Y312-Y426 VanDerWaalsContact CE2-CD2 3.48Å; Y312-Y426 AromaticContact CE2-CE2 3.44Å; Y312-Y426 HydrophobicContact CE2-CE2 3.44Å; Y312-Y426 VanDerWaalsContact CE2-CE2 3.44Å; Y312-Y426 HydrophobicContact CE2-CG 4.38Å; Y312-Y426 AromaticContact CZ-CD2 3.58Å; Y312-Y426 AromaticContact CZ-CE2 3.93Å; Y312-Y426 VanDerWaalsContact OH-CD2 3.31Å; Y312-Y426 WeakPolarHBondContact OH-CD2 3.34Å; N422-Y426 WeakPolarHBondContact O-CD2 3.41Å; N422-Y426 PolarHBondContact O-N 2.97Å; I424-Y426 PolarHBondContact O-N 3.32Å; Y426-A430 VanDerWaalsContact O-CB 3.29Å; Y426-A430 WeakPolarHBondContact O-CB 3.48Å; Y426-A430 PolarHBondContact O-N 3.49Å
427	R	82.5	Confident	84.9	Confident	160 Å²	160	85.5 Å²	85.5	60%	0.604	39%	0.39	S	S	*	.	H	α-helix	trans	-65.8	-41.4	176	-83.5	-172	161.3	-167	-2	112.5	F423 I424 N425 A430 K431	F423-R427 HydrophobicContact CE1-CG 4.41Å; F423-R427 HydrophobicContact CZ-CG 4.44Å; F423-R427 VanDerWaalsContact CZ-CZ 3.47Å; F423-R427 PolarHBondContact O-N 3.03Å; I424-R427 PolarHBondContact O-N 3.43Å; N425-R427 VanDerWaalsContact C-N 3.34Å; N425-R427 PolarHBondContact O-N 3.08Å; R427-A430 PolarHBondContact O-N 3.35Å; R427-K431 WeakPolarHBondContact O-CG 3.45Å; R427-K431 PolarHBondContact O-N 3.22Å
428	L	79.7	Confident	84.1	Confident	64 Å²	64	85 Å²	85	34%	0.335	40%	0.395	S	S	.	.	H	α-helix	trans	-67.2	-46.5	177.6	-72	170.1	0	0	0	110.9	I424 N425 A430 K431 E432	I424-L428 HydrophobicContact CG2-CD1 3.81Å; I424-L428 HydrophobicContact CG2-CG 4.35Å; I424-L428 WeakPolarHBondContact O-CG 3.34Å; I424-L428 PolarHBondContact O-N 3.08Å; N425-L428 PolarHBondContact O-N 3.34Å; L428-A430 VanDerWaalsContact C-N 3.25Å; L428-A430 PolarHBondContact O-N 3.1Å; L428-K431 WeakPolarHBondContact O-CA 3.36Å; L428-K431 WeakPolarHBondContact O-CB 3.35Å; L428-K431 PolarHBondContact O-N 3.45Å; L428-E432 WeakPolarHBondContact O-CG 3.31Å; L428-E432 PolarHBondContact O-N 2.96Å
429	L	81.6	Confident	83.4	Confident	56 Å²	56	92.2 Å²	92.2	29%	0.293	42%	0.423	S	S	.	.	H	α-helix	trans	-58.6	-37.3	174.4	-78.2	160.7	0	0	0	112.3	N425 R433	N425-L429 WeakPolarHBondContact O-CB 3.43Å; N425-L429 WeakPolarHBondContact O-CD1 2.82Å; N425-L429 WeakPolarHBondContact O-CG 3.29Å; N425-L429 PolarHBondContact O-N 3.17Å; L429-R433 WeakPolarHBondContact O-CG 3.36Å; L429-R433 PolarHBondContact O-N 3.21Å
430	A	81.3	Confident	82.7	Confident	48 Å²	48	93.6 Å²	93.6	40%	0.397	43%	0.429	S	S	.	.	H	α-helix	trans	-69.4	-34	175.1	0	0	0	0	0	112.5	Y426 R427 L428 K434	Y426-A430 VanDerWaalsContact O-CB 3.29Å; Y426-A430 WeakPolarHBondContact O-CB 3.48Å; Y426-A430 PolarHBondContact O-N 3.49Å; R427-A430 PolarHBondContact O-N 3.35Å; L428-A430 VanDerWaalsContact C-N 3.25Å; L428-A430 PolarHBondContact O-N 3.1Å; A430-K434 VanDerWaalsContact O-CG 3.31Å; A430-K434 WeakPolarHBondContact O-CG 3.34Å; A430-K434 PolarHBondContact O-N 3.26Å
431	K	81.6	Confident	81.9	Confident	137 Å²	137	97.2 Å²	97.2	60%	0.596	44%	0.437	S	S	*	.	H	α-helix	trans	-68.9	-43.9	173.4	-75.4	-179	177.6	-171.9	0	111.6	R427 L428 K434 Q435	R427-K431 WeakPolarHBondContact O-CG 3.45Å; R427-K431 PolarHBondContact O-N 3.22Å; L428-K431 WeakPolarHBondContact O-CA 3.36Å; L428-K431 WeakPolarHBondContact O-CB 3.35Å; L428-K431 PolarHBondContact O-N 3.45Å; K431-K434 PolarHBondContact O-N 2.99Å; K431-Q435 WeakPolarHBondContact O-CG 3.35Å; K431-Q435 PolarHBondContact O-N 3.02Å
432	E	83.6	Confident	81.2	Confident	68 Å²	68	101.2 Å²	101.2	32%	0.318	46%	0.459	S	S	.	.	H	α-helix	trans	-61.7	-45.2	178.2	-72	168.8	178.4	0	0	110.8	R242 L428 K434 Q435 E436	R242-E432 IonicContact CZ-OE1 3Å; R242-E432 IonicContact NH1-OE1 2.7Å; R242-E432 PolarHBondContact NH1-OE1 3.03Å; L428-E432 WeakPolarHBondContact O-CG 3.31Å; L428-E432 PolarHBondContact O-N 2.96Å; E432-K434 PolarHBondContact O-N 3.46Å; E432-Q435 PolarHBondContact O-N 3.42Å; E432-Q435 VanDerWaalsContact O-N 3.13Å; E432-E436 PolarHBondContact O-N 3.32Å
433	R	81.9	Confident	80.3	Confident	153 Å²	153	105.2 Å²	105.2	58%	0.577	48%	0.478	S	S	*	.	H	α-helix	trans	-59.5	-43.2	173.8	-74.3	-176.3	-136.9	-154.1	0.5	113.1	L429 Q435 E436 E437	L429-R433 WeakPolarHBondContact O-CG 3.36Å; L429-R433 PolarHBondContact O-N 3.21Å; R433-Q435 VanDerWaalsContact C-N 3.31Å; R433-Q435 PolarHBondContact O-N 2.8Å; R433-E436 PolarHBondContact O-N 3.41Å; R433-E437 WeakPolarHBondContact O-CB 3.43Å; R433-E437 WeakPolarHBondContact O-CG 3.04Å; R433-E437 PolarHBondContact O-N 3.11Å
434	K	82.6	Confident	79.1	Confident	142 Å²	142	106.7 Å²	106.7	62%	0.617	49%	0.494	S	S	*	.	H	α-helix	trans	-63.7	-36.9	176	-74.9	179.5	178.5	-167.3	0	112	A430 K431 E432 M438	A430-K434 VanDerWaalsContact O-CG 3.31Å; A430-K434 WeakPolarHBondContact O-CG 3.34Å; A430-K434 PolarHBondContact O-N 3.26Å; K431-K434 PolarHBondContact O-N 2.99Å; E432-K434 PolarHBondContact O-N 3.46Å; K434-M438 WeakPolarHBondContact O-CB 3.36Å; K434-M438 WeakPolarHBondContact O-CG 3.42Å; K434-M438 PolarHBondContact O-N 3.09Å
435	Q	81.6	Confident	77.8	Confident	136 Å²	136	109.5 Å²	109.5	64%	0.636	51%	0.505	S	S	*	.	H	α-helix	trans	-68.4	-40.6	175.9	-75.3	176.3	-31.3	0	0	111.9	K431 E432 R433 M438 Y439	K431-Q435 WeakPolarHBondContact O-CG 3.35Å; K431-Q435 PolarHBondContact O-N 3.02Å; E432-Q435 PolarHBondContact O-N 3.42Å; E432-Q435 VanDerWaalsContact O-N 3.13Å; R433-Q435 VanDerWaalsContact C-N 3.31Å; R433-Q435 PolarHBondContact O-N 2.8Å; Q435-M438 PolarHBondContact O-N 3.4Å; Q435-Y439 WeakPolarHBondContact O-CB 3.29Å; Q435-Y439 PolarHBondContact O-N 3.04Å
436	E	81.1	Confident	76.2	Confident	119 Å²	119	112.7 Å²	112.7	56%	0.556	52%	0.522	S	S	*	.	H	α-helix	trans	-64.4	-41	173.8	-72.8	178.6	-178.2	0	0	112.2	E432 R433 Y439 K440	E432-E436 PolarHBondContact O-N 3.32Å; R433-E436 PolarHBondContact O-N 3.41Å; E436-Y439 PolarHBondContact O-N 3.45Å; E436-K440 WeakPolarHBondContact O-CB 3.44Å; E436-K440 WeakPolarHBondContact O-CG 3.46Å; E436-K440 PolarHBondContact O-N 3.35Å
437	E	82.9	Confident	74.8	Confident	127 Å²	127	114 Å²	114	59%	0.593	54%	0.538	S	S	*	.	H	α-helix	trans	-64	-40.5	174.6	-75.4	171.9	-174.4	0	0	111.8	R433 R441	R433-E437 WeakPolarHBondContact O-CB 3.43Å; R433-E437 WeakPolarHBondContact O-CG 3.04Å; R433-E437 PolarHBondContact O-N 3.11Å; E437-R441 WeakPolarHBondContact O-CB 3.39Å; E437-R441 PolarHBondContact O-N 2.91Å
438	M	78.1	Confident	73.5	Confident	122 Å²	122	111.3 Å²	111.3	60%	0.601	54%	0.535	S	S	*	.	H	α-helix	trans	-65.9	-45.8	174.8	-71	-74.9	-78	0	0	111.4	K434 Q435 K440 R441 T442	K434-M438 WeakPolarHBondContact O-CB 3.36Å; K434-M438 WeakPolarHBondContact O-CG 3.42Å; K434-M438 PolarHBondContact O-N 3.09Å; Q435-M438 PolarHBondContact O-N 3.4Å; M438-K440 PolarHBondContact O-N 3.11Å; M438-R441 WeakPolarHBondContact O-CB 3.34Å; M438-R441 PolarHBondContact O-N 3.41Å; M438-T442 PolarHBondContact O-N 2.92Å; M438-T442 PolarHBondContact O-OG1 3.4Å
439	Y	78.7	Confident	72.2	Confident	152 Å²	152	116.2 Å²	116.2	60%	0.596	55%	0.549	S	S	*	.	H	α-helix	trans	-60.5	-45.3	177.5	-175.8	-99.6	0	0	0	112	Q435 E436 R441 T442 E443	Q435-Y439 WeakPolarHBondContact O-CB 3.29Å; Q435-Y439 PolarHBondContact O-N 3.04Å; E436-Y439 PolarHBondContact O-N 3.45Å; Y439-R441 VanDerWaalsContact C-N 3.31Å; Y439-R441 PolarHBondContact O-N 3.44Å; Y439-T442 PolarHBondContact O-N 3.36Å; Y439-E443 HydrophobicContact CD1-CG 4.31Å; Y439-E443 HydrophobicContact CE1-CG 3.93Å; Y439-E443 VanDerWaalsContact CE1-OE1 3.24Å; Y439-E443 WeakPolarHBondContact CE1-OE1 3.13Å; Y439-E443 PolarHBondContact O-N 3.14Å; Y439-E443 PolarHBondContact OH-OE1 3.18Å
440	K	77.8	Confident	70.6	Confident	136 Å²	136	118.9 Å²	118.9	59%	0.591	56%	0.564	S	S	*	*	H	α-helix	trans	-62.2	-37.7	175.1	-75.4	179.1	-179.1	178.1	0	112.6	E436 M438 T444	E436-K440 WeakPolarHBondContact O-CB 3.44Å; E436-K440 WeakPolarHBondContact O-CG 3.46Å; E436-K440 PolarHBondContact O-N 3.35Å; M438-K440 PolarHBondContact O-N 3.11Å; K440-T444 PolarHBondContact O-N 3.47Å; K440-T444 VanDerWaalsContact O-N 3.17Å; K440-T444 PolarHBondContact O-OG1 3.08Å
441	R	73.8	Confident	69.1	Low	166 Å²	166	122.5 Å²	122.5	63%	0.626	57%	0.573	S	S	*	*	H	α-helix	trans	-63.5	-45.9	173.2	-94.8	-174	176	-173.5	-3.5	111.6	E437 M438 Y439 E443 T444 E445	E437-R441 WeakPolarHBondContact O-CB 3.39Å; E437-R441 PolarHBondContact O-N 2.91Å; M438-R441 WeakPolarHBondContact O-CB 3.34Å; M438-R441 PolarHBondContact O-N 3.41Å; Y439-R441 VanDerWaalsContact C-N 3.31Å; Y439-R441 PolarHBondContact O-N 3.44Å; R441-E443 VanDerWaalsContact C-N 3.35Å; R441-E443 PolarHBondContact O-N 2.88Å; R441-T444 WeakPolarHBondContact CA-OG1 3.46Å; R441-T444 PolarHBondContact O-N 3.48Å; R441-T444 VanDerWaalsContact O-N 3.13Å; R441-T444 PolarHBondContact O-OG1 3.19Å; R441-E445 WeakPolarHBondContact O-CB 3.26Å; R441-E445 WeakPolarHBondContact O-CG 3.26Å; R441-E445 PolarHBondContact O-N 3.37Å
442	T	72.8	Confident	67.5	Low	93 Å²	93	121.1 Å²	121.1	57%	0.571	57%	0.572	S	S	*	*	H	α-helix	trans	-64.5	-36.4	178.5	-47.3	0	0	0	0	112.2	M438 Y439 T444 E445 D446	M438-T442 PolarHBondContact O-N 2.92Å; M438-T442 PolarHBondContact O-OG1 3.4Å; Y439-T442 PolarHBondContact O-N 3.36Å; T442-T444 VanDerWaalsContact C-N 3.33Å; T442-T444 PolarHBondContact O-N 3.32Å; T442-E445 PolarHBondContact O-N 2.93Å; T442-D446 PolarHBondContact O-N 3.29Å
443	E	68.7	Low	65.8	Low	90 Å²	90	123.7 Å²	123.7	42%	0.421	58%	0.584	S	S	.	*	H	α-helix	trans	-67.6	-27.7	172.2	-78.4	-171.8	147.5	0	0	113.9	Y439 R441	Y439-E443 HydrophobicContact CD1-CG 4.31Å; Y439-E443 HydrophobicContact CE1-CG 3.93Å; Y439-E443 VanDerWaalsContact CE1-OE1 3.24Å; Y439-E443 WeakPolarHBondContact CE1-OE1 3.13Å; Y439-E443 PolarHBondContact O-N 3.14Å; Y439-E443 PolarHBondContact OH-OE1 3.18Å; R441-E443 VanDerWaalsContact C-N 3.35Å; R441-E443 PolarHBondContact O-N 2.88Å
444	T	59.3	Low	64.3	Low	117 Å²	117	124.2 Å²	124.2	72%	0.718	59%	0.59	S	S	*	*	H	α-helix	trans	-87.8	-19	176	45.5	0	0	0	0	114	K440 R441 T442	K440-T444 PolarHBondContact O-N 3.47Å; K440-T444 VanDerWaalsContact O-N 3.17Å; K440-T444 PolarHBondContact O-OG1 3.08Å; R441-T444 WeakPolarHBondContact CA-OG1 3.46Å; R441-T444 PolarHBondContact O-N 3.48Å; R441-T444 VanDerWaalsContact O-N 3.13Å; R441-T444 PolarHBondContact O-OG1 3.19Å; T442-T444 VanDerWaalsContact C-N 3.33Å; T442-T444 PolarHBondContact O-N 3.32Å
445	E	57	Low	62.7	Low	143 Å²	143	124 Å²	124	67%	0.668	59%	0.591	S	S	*	*	S	Bend	trans	-101.5	7.2	179.3	-71.1	178.5	163.7	0	0	112.4	R441 T442 P447	R441-E445 WeakPolarHBondContact O-CB 3.26Å; R441-E445 WeakPolarHBondContact O-CG 3.26Å; R441-E445 PolarHBondContact O-N 3.37Å; T442-E445 PolarHBondContact O-N 2.93Å; E445-P447 WeakPolarHBondContact O-CD 3.14Å
446	D	50.4	Low	61.3	Low	80 Å²	80	121.8 Å²	121.8	43%	0.428	59%	0.587	S	S	.	*			trans	-69.4	109.2	-179.6	-158.8	-3.6	0	0	0	110.9	T442 D448 R449	T442-D446 PolarHBondContact O-N 3.29Å; D446-D448 PolarHBondContact O-N 3.28Å; D446-R449 PolarHBondContact O-N 2.99Å
447	P	54.8	Low	59.9	Low	86 Å²	86	121.3 Å²	121.3	56%	0.558	59%	0.589	S	S	*	*	H	α-helix	trans	-69.4	-16.7	-174.1	19.3	-18.7	0	0	0	113.8	E445 R449 D450 Q451	E445-P447 WeakPolarHBondContact O-CD 3.14Å; P447-R449 VanDerWaalsContact C-N 3.28Å; P447-R449 PolarHBondContact O-N 3.07Å; P447-D450 PolarHBondContact O-N 2.91Å; P447-Q451 PolarHBondContact O-N 3.29Å
448	D	55.3	Low	58.5	Low	102 Å²	102	117 Å²	117	55%	0.545	58%	0.578	S	S	.	*	H	α-helix	trans	-70.5	-25	178	-75.8	-13.7	0	0	0	112	D446 Q451 D452	D446-D448 PolarHBondContact O-N 3.28Å; D448-Q451 PolarHBondContact O-N 3.24Å; D448-D452 PolarHBondContact O-N 3.13Å
449	R	51.2	Low	57.2	Low	167 Å²	167	116.6 Å²	116.6	63%	0.63	58%	0.578	S	S	*	*	H	α-helix	trans	-75.2	-34.4	176.8	-124.2	179.5	-179.4	169.1	1.9	113.3	D446 P447 Q451 Q453	D446-R449 PolarHBondContact O-N 2.99Å; P447-R449 VanDerWaalsContact C-N 3.28Å; P447-R449 PolarHBondContact O-N 3.07Å; R449-Q451 VanDerWaalsContact C-N 3.32Å; R449-Q453 WeakPolarHBondContact O-CB 3.4Å; R449-Q453 PolarHBondContact O-N 3.33Å; R449-Q453 VanDerWaalsContact O-N 3.15Å
450	D	48.6	Very low	55.9	Low	112 Å²	112	111.7 Å²	111.7	60%	0.599	57%	0.57	S	S	*	*	H	α-helix	trans	-74.4	-23.6	173.4	-87.3	-19.4	0	0	0	111.9	P447 K454	P447-D450 PolarHBondContact O-N 2.91Å; D450-K454 WeakPolarHBondContact O-CB 3.16Å; D450-K454 WeakPolarHBondContact O-CG 3.39Å; D450-K454 PolarHBondContact O-N 2.84Å
451	Q	49.2	Very low	54.7	Low	125 Å²	125	111.6 Å²	111.6	58%	0.584	57%	0.571	S	S	*	*	H	α-helix	trans	-78.2	-46.5	171.5	-80.6	-175.3	-10.7	0	0	112	P447 D448 R449 Q453 K454 E455	P447-Q451 PolarHBondContact O-N 3.29Å; D448-Q451 PolarHBondContact O-N 3.24Å; R449-Q451 VanDerWaalsContact C-N 3.32Å; Q451-Q453 VanDerWaalsContact C-N 3.3Å; Q451-Q453 PolarHBondContact O-N 2.91Å; Q451-K454 PolarHBondContact O-N 3.38Å; Q451-K454 VanDerWaalsContact O-N 3.13Å; Q451-E455 PolarHBondContact O-N 2.79Å
452	D	48.8	Very low	53.6	Low	108 Å²	108	106.1 Å²	106.1	58%	0.578	56%	0.561	S	S	*	*	H	α-helix	trans	-60.7	-37.5	176.3	-90.3	-17.6	0	0	0	112.1	D448 T456	D448-D452 PolarHBondContact O-N 3.13Å; D452-T456 PolarHBondContact O-N 3.48Å; D452-T456 PolarHBondContact O-OG1 2.78Å
453	Q	47	Very low	52.5	Low	121 Å²	121	107.8 Å²	107.8	57%	0.565	57%	0.566	S	S	*	*	H	α-helix	trans	-69.9	-34.1	174.6	-90.3	-177.8	-38.9	0	0	113.4	R449 Q451 T456 D457	R449-Q453 WeakPolarHBondContact O-CB 3.4Å; R449-Q453 PolarHBondContact O-N 3.33Å; R449-Q453 VanDerWaalsContact O-N 3.15Å; Q451-Q453 VanDerWaalsContact C-N 3.3Å; Q451-Q453 PolarHBondContact O-N 2.91Å; Q453-T456 WeakPolarHBondContact CA-OG1 3.46Å; Q453-T456 PolarHBondContact O-OG1 3.32Å; Q453-D457 WeakPolarHBondContact O-CB 3.16Å; Q453-D457 PolarHBondContact O-N 3.07Å
454	K	49.7	Very low	51.6	Low	164 Å²	164	110.7 Å²	110.7	71%	0.713	58%	0.58	S	S	*	*	H	α-helix	trans	-73.8	-33.6	175.4	-83.4	178.1	178.8	172.2	0	113	D450 Q451 G458	D450-K454 WeakPolarHBondContact O-CB 3.16Å; D450-K454 WeakPolarHBondContact O-CG 3.39Å; D450-K454 PolarHBondContact O-N 2.84Å; Q451-K454 PolarHBondContact O-N 3.38Å; Q451-K454 VanDerWaalsContact O-N 3.13Å; K454-G458 PolarHBondContact O-N 3.32Å
455	E	50.8	Low	51.2	Low	137 Å²	137	112.4 Å²	112.4	64%	0.64	58%	0.584	S	S	*	*	H	α-helix	trans	-70.4	-40	173.2	-75.8	-169.8	163.5	0	0	111.3	Q451 G458 D459	Q451-E455 PolarHBondContact O-N 2.79Å; E455-G458 PolarHBondContact O-N 2.7Å; E455-D459 WeakPolarHBondContact O-CB 3.33Å; E455-D459 PolarHBondContact O-N 2.96Å
456	T	50.7	Low	50.6	Low	90 Å²	90	113.4 Å²	113.4	55%	0.552	59%	0.591	S	S	*	*	H	α-helix	trans	-70.1	-37.6	176.1	30.1	0	0	0	0	114	D452 Q453 A460	D452-T456 PolarHBondContact O-N 3.48Å; D452-T456 PolarHBondContact O-OG1 2.78Å; Q453-T456 WeakPolarHBondContact CA-OG1 3.46Å; Q453-T456 PolarHBondContact O-OG1 3.32Å; T456-A460 WeakPolarHBondContact O-CB 3.37Å; T456-A460 PolarHBondContact O-N 3.24Å; T456-A460 VanDerWaalsContact O-N 3.1Å
457	D	52	Low	50.3	Low	110 Å²	110	114.8 Å²	114.8	59%	0.588	60%	0.602	S	S	*	*	H	α-helix	trans	-71.7	-32.6	173.8	-80.2	-17	0	0	0	112	Q453 Q461	Q453-D457 WeakPolarHBondContact O-CB 3.16Å; Q453-D457 PolarHBondContact O-N 3.07Å; D457-Q461 PolarHBondContact O-N 3.23Å
458	G	52.9	Low	49.6	Very low	35 Å²	35	116.4 Å²	116.4	36%	0.361	61%	0.606	S	S	.	*	H	α-helix	trans	-68.5	-41	175.1	0	0	0	0	0	113.4	K454 E455 A462	K454-G458 PolarHBondContact O-N 3.32Å; E455-G458 PolarHBondContact O-N 2.7Å; G458-A462 WeakPolarHBondContact O-CB 3.17Å; G458-A462 PolarHBondContact O-N 3.46Å; G458-A462 VanDerWaalsContact O-N 3.08Å
459	D	52.1	Low	49	Very low	114 Å²	114	117.3 Å²	117.3	61%	0.61	62%	0.617	S	S	*	*	H	α-helix	trans	-70.2	-34.7	174.7	-85.8	-14.1	0	0	0	112	E455 A462 L463	E455-D459 WeakPolarHBondContact O-CB 3.33Å; E455-D459 PolarHBondContact O-N 2.96Å; D459-A462 PolarHBondContact O-N 2.68Å; D459-L463 WeakPolarHBondContact O-CB 3.38Å; D459-L463 WeakPolarHBondContact O-CD1 3.47Å; D459-L463 PolarHBondContact O-N 2.79Å; D459-L463 VanDerWaalsContact O-N 3.14Å
460	A	51.9	Low	48.4	Very low	50 Å²	50	117.8 Å²	117.8	41%	0.413	62%	0.624	S	S	.	*	H	α-helix	trans	-67.2	-40.5	175.3	0	0	0	0	0	112.6	T456 L463 E464	T456-A460 WeakPolarHBondContact O-CB 3.37Å; T456-A460 PolarHBondContact O-N 3.24Å; T456-A460 VanDerWaalsContact O-N 3.1Å; A460-L463 PolarHBondContact O-N 3.29Å; A460-E464 PolarHBondContact O-N 3.11Å; A460-E464 VanDerWaalsContact O-N 3.14Å
461	Q	51.1	Low	48	Very low	133 Å²	133	118.8 Å²	118.8	62%	0.621	63%	0.63	S	S	*	*	H	α-helix	trans	-69.3	-35.6	174.8	-88.1	177.2	-27.5	0	0	113	D457 L463 E464 D465	D457-Q461 PolarHBondContact O-N 3.23Å; Q461-L463 VanDerWaalsContact C-N 3.27Å; Q461-L463 PolarHBondContact O-N 3.35Å; Q461-E464 PolarHBondContact O-N 3.13Å; Q461-D465 PolarHBondContact O-N 3.5Å; Q461-D465 VanDerWaalsContact O-N 3.16Å
462	A	51.8	Low	47.4	Very low	51 Å²	51	121.1 Å²	121.1	42%	0.421	64%	0.641	S	S	.	*	H	α-helix	trans	-68.3	-25.7	174.8	0	0	0	0	0	113.1	G458 D459	G458-A462 WeakPolarHBondContact O-CB 3.17Å; G458-A462 PolarHBondContact O-N 3.46Å; G458-A462 VanDerWaalsContact O-N 3.08Å; D459-A462 PolarHBondContact O-N 2.68Å
463	L	49.4	Very low	46.8	Very low	129 Å²	129	124 Å²	124	68%	0.675	66%	0.656	S	S	*	*	H	α-helix	trans	-79.9	-32.5	174.2	-93.3	148.1	0	0	0	113	D459 A460 Q461	D459-L463 WeakPolarHBondContact O-CB 3.38Å; D459-L463 WeakPolarHBondContact O-CD1 3.47Å; D459-L463 PolarHBondContact O-N 2.79Å; D459-L463 VanDerWaalsContact O-N 3.14Å; A460-L463 PolarHBondContact O-N 3.29Å; Q461-L463 VanDerWaalsContact C-N 3.27Å; Q461-L463 PolarHBondContact O-N 3.35Å
464	E	49.7	Very low	46.2	Very low	151 Å²	151	122.3 Å²	122.3	71%	0.706	66%	0.662	S	S	*	*	H	α-helix	trans	-73.6	-35.6	175.2	-81.6	-176.1	155.1	0	0	112.9	A460 Q461 M466 V467	A460-E464 PolarHBondContact O-N 3.11Å; A460-E464 VanDerWaalsContact O-N 3.14Å; Q461-E464 PolarHBondContact O-N 3.13Å; E464-M466 PolarHBondContact O-N 2.98Å; E464-V467 PolarHBondContact O-N 2.68Å
465	D	50.6	Low	45.5	Very low	152 Å²	152	122.1 Å²	122.1	81%	0.813	67%	0.666	S	S	*	*	T	Hydrogen-bonded Turn	trans	-73.7	-7.2	178.7	-86.9	-17.5	0	0	0	114.2	Q461	Q461-D465 PolarHBondContact O-N 3.5Å; Q461-D465 VanDerWaalsContact O-N 3.16Å
466	M	44.8	Very low	44.8	Very low	165 Å²	165	124.5 Å²	124.5	81%	0.813	68%	0.677	S	S	*	*	T	Hydrogen-bonded Turn	trans	-96.7	1.2	175.4	-70.6	-156.7	-165.2	0	0	114.5	E464	E464-M466 PolarHBondContact O-N 2.98Å
467	V	43.5	Very low	44.1	Very low	109 Å²	109	131.6 Å²	131.6	66%	0.661	69%	0.694	S	S	*	*			trans	-101.6	103.2	178.6	-175.7	0	0	0	0	110	E464	E464-V467 PolarHBondContact O-N 2.68Å
468	D	41.1	Very low	43.3	Very low	119 Å²	119	134.7 Å²	134.7	64%	0.636	71%	0.705	S	S	*	*			trans	-64.8	126.1	174.8	-165.2	-13.2	0	0	0	109.8	K470	D468-K470 PolarHBondContact O-N 3.12Å
469	P	41.3	Very low	42.4	Very low	121 Å²	121	140 Å²	140	79%	0.786	73%	0.73	S	S	*	*	T	Hydrogen-bonded Turn	trans	-68.8	18.1	-171.2	-19	31.5	0	0	0	116.4
470	K	38.6	Very low	41.4	Very low	177 Å²	177	142.4 Å²	142.4	77%	0.77	74%	0.743	S	S	*	*	T	Hydrogen-bonded Turn	trans	-103.1	-3.3	-171.2	-85.1	-175.5	176.2	175	0	116.5	D468	D468-K470 PolarHBondContact O-N 3.12Å
471	D	40.2	Very low	40.7	Very low	134 Å²	134	151.8 Å²	151.8	72%	0.717	78%	0.784	S	S	*	*	S	Bend	trans	-108.7	-2.3	-176.2	-85.5	-28.2	0	0	0	115.9
472	E	37.3	Very low	40.2	Very low	174 Å²	174	152.7 Å²	152.7	81%	0.813	79%	0.792	S	S	*	*	G	3₁₀ helix	trans	-78.1	-21.1	179.8	-80.9	-166.6	141.7	0	0	114.6	A474	E472-A474 VanDerWaalsContact C-N 3.32Å; E472-A474 PolarHBondContact O-N 3.27Å
473	D	35.7	Very low	39.5	Very low	168 Å²	168	158.1 Å²	158.1	90%	0.898	81%	0.811	S	S	*	*	G	3₁₀ helix	trans	-81.9	-4.8	-176.7	-100.8	-19.2	0	0	0	114.4
474	A	35.7	Very low	39	Very low	85 Å²	85	159.7 Å²	159.7	70%	0.702	82%	0.819	S	S	*	*	G	3₁₀ helix	trans	-93.4	-16.2	-177.1	0	0	0	0	0	114.5	E472	E472-A474 VanDerWaalsContact C-N 3.32Å; E472-A474 PolarHBondContact O-N 3.27Å
475	M	34.9	Very low	38.4	Very low	161 Å²	161	160.2 Å²	160.2	79%	0.793	83%	0.826	S	S	*	*	S	Bend	trans	-100.6	-8.5	-166.2	-136.8	178.9	-63.1	0	0	115.3	R477	M475-R477 PolarHBondContact O-N 3.12Å
476	Q	35	Very low	37.6	Very low	186 Å²	186	160.7 Å²	160.7	87%	0.869	83%	0.826	S	S	*	*	T	Hydrogen-bonded Turn	trans	-90.5	11.9	-177.2	-73.1	-171.2	-4.8	0	0	115.4
477	R	35.8	Very low	37.1	Very low	239 Å²	239	160.4 Å²	160.4	90%	0.902	83%	0.827	S	S	*	*	T	Hydrogen-bonded Turn	trans	-106.1	-2.6	-178.6	-102.9	-174.9	-178.3	-177.5	3	117.2	M475	M475-R477 PolarHBondContact O-N 3.12Å
478	E	36.8	Very low	36.7	Very low	176 Å²	176	164.1 Å²	164.1	82%	0.822	84%	0.839	S	S	*	*	S	Bend	trans	-122	87.7	176.1	-72.9	-168.5	154.4	0	0	111.1
479	T	33.7	Very low	36.3	Very low	145 Å²	145	167.5 Å²	167.5	89%	0.89	86%	0.855	S	S	*	*			trans	179.2	68	147.7	31.4	0	0	0	0	109.3
480	N	31.3	Very low	35.9	Very low	166 Å²	166	171.4 Å²	171.4	89%	0.888	86%	0.86	S	S	*	*			trans	-121.8	91.9	158.2	-101.8	-21.8	0	0	0	106.8
481	I	36.1	Very low	35.7	Very low	246 Å²	246	170.9 Å²	170.9	100%	1.262	87%	0.869	S	S	*	*			trans	-151.5	0	142.2	-58.3	-168.4	0	0	0	107.5

Retrieved 481 of 481 residues in 103.2 ms (Link to these results)

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