A0A060WLI6_ONCMY Loading...

GTP cyclohydrolase 1 feedback regulatory protein

AlphaFold DB , UniProt , Accession A0A060WLI6, Species ONCMY (Oncorhynchus mykiss, Rainbow trout), Gene LOC110505495, Length 89 aa.

Structure Viewer
Loading PAE data...
(Predicted Aligned Error values between residue pairs)
Error loading PAE data: please refresh the page.

 

Download Structure   PDB   PAE   Table  
Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M85.3Confident96.1Very high93 Ų9376.1 Ų76.146%0.45836%0.357SS..  0100.90178.8172.8-71.200108.7Y3 Y23 D25M1-Y3 VanDerWaalsContact CG-O 3.31Å; M1-Y3 WeakPolarHBondContact CG-O 3.22Å; M1-Y23 VanDerWaalsContact CE-O 3.29Å; M1-Y23 WeakPolarHBondContact CE-O 3.34Å; M1-D25 HydrophobicContact CB-CB 4.41Å; M1-D25 HydrophobicContact SD-CB 4.49Å
2P94.8Very high96Very high38 Ų3875.9 Ų75.925%0.24736%0.36CS..  trans-76.2-24.2-171.927.7-33.5000114Y82 K83 T85P2-Y82 HydrophobicContact CB-CD2 4.24Å; P2-Y82 HydrophobicContact CB-CE2 3.9Å; P2-Y82 CarbonylContact O-C 3.55Å; P2-Y82 VanDerWaalsContact O-CA 3.29Å; P2-Y82 WeakPolarHBondContact O-CA 3.47Å; P2-Y82 WeakPolarHBondContact O-CD2 3.44Å; P2-K83 PolarHBondContact O-N 2.85Å; P2-T85 HydrophobicContact CB-CG2 4.02Å
3Y97.8Very high96.1Very high132 Ų13281.5 Ų81.552%0.51839%0.385SS..EExtended strand (participates in β ladder)trans-115.6144.3178.6-73.5-84.4000111.4M1 M81 Y82M1-Y3 VanDerWaalsContact CG-O 3.31Å; M1-Y3 WeakPolarHBondContact CG-O 3.22Å; Y3-M81 VanDerWaalsContact CA-O 3.3Å; Y3-M81 WeakPolarHBondContact CA-O 3.31Å; Y3-Y82 AromaticContact CD1-CD2 3.9Å; Y3-Y82 HydrophobicContact CD1-CD2 3.9Å; Y3-Y82 HydrophobicContact CD1-CG 4.4Å; Y3-Y82 AromaticContact CD2-CD2 3.96Å; Y3-Y82 HydrophobicContact CD2-CD2 3.96Å; Y3-Y82 HydrophobicContact CD2-CE2 4.44Å; Y3-Y82 AromaticContact CE1-CD2 3.5Å; Y3-Y82 HydrophobicContact CE1-CD2 3.5Å; Y3-Y82 VanDerWaalsContact CE1-CD2 3.5Å; Y3-Y82 HydrophobicContact CE1-CE2 4.48Å; Y3-Y82 AromaticContact CE1-CG 3.95Å; Y3-Y82 HydrophobicContact CE1-CG 3.95Å; Y3-Y82 AromaticContact CE2-CD2 3.53Å; Y3-Y82 HydrophobicContact CE2-CD2 3.53Å; Y3-Y82 AromaticContact CE2-CE2 3.82Å; Y3-Y82 HydrophobicContact CE2-CE2 3.82Å; Y3-Y82 HydrophobicContact CG-CD2 4.12Å; Y3-Y82 AromaticContact CZ-CD2 3.28Å; Y3-Y82 AromaticContact CZ-CE2 3.84Å
4V97.7Very high96.2Very high7 Ų781.5 Ų81.54%0.04239%0.394CS..EExtended strand (participates in β ladder)trans-134.2138171.1174.70000108.8V6 F65 M81V4-V6 HydrophobicContact CG1-CG2 3.99Å; V4-F65 HydrophobicContact CB-CE1 4.28Å; V4-F65 HydrophobicContact CG2-CD1 4.4Å; V4-F65 HydrophobicContact CG2-CE1 3.65Å; V4-F65 HydrophobicContact CG2-CZ 3.78Å; V4-M81 PolarHBondContact N-O 3.49Å; V4-M81 PolarHBondContact O-N 3.29Å
5L98.6Very high96.1Very high114 Ų11477.1 Ų77.160%0.59738%0.379SS*.EExtended strand (participates in β ladder)trans-104.6120.5170.6-60.7-178.8000108.7W79 C80L5-W79 WeakPolarHBondContact CA-O 3.25Å; L5-C80 HydrophobicContact CD2-CB 3.92Å
6V98.6Very high96.2Very high0 Ų076.9 Ų76.90%039%0.385CS..EExtended strand (participates in β ladder)trans-108.6136.1176179.90000107.8V4 T17 M18 V56 L60 V78 W79V4-V6 HydrophobicContact CG1-CG2 3.99Å; V6-T17 HydrophobicContact CG1-CG2 3.3Å; V6-M18 CarbonylContact C-O 3.51Å; V6-M18 WeakPolarHBondContact CA-O 3.31Å; V6-V56 HydrophobicContact CG1-CG1 3.96Å; V6-V56 HydrophobicContact CG2-CG1 4.28Å; V6-L60 HydrophobicContact CG2-CD1 3.53Å; V6-V78 CarbonylContact O-C 3.57Å; V6-V78 VanDerWaalsContact O-CA 3.31Å; V6-V78 WeakPolarHBondContact O-CA 3.17Å; V6-W79 PolarHBondContact N-O 2.91Å; V6-W79 PolarHBondContact O-N 3.13Å
7S98.8Very high96.4Very high29 Ų2972.4 Ų72.420%0.20336%0.362CS..EExtended strand (participates in β ladder)trans-140.7155.1175.672.10000113.4T17 M18 L77S7-T17 CarbonylContact O-C 3.58Å; S7-T17 WeakPolarHBondContact O-CA 3.44Å; S7-T17 WeakPolarHBondContact O-CG2 3.34Å; S7-M18 PolarHBondContact N-O 3.3Å; S7-M18 PolarHBondContact O-N 3.44Å; S7-L77 CarbonylContact C-O 3.57Å; S7-L77 WeakPolarHBondContact CA-O 3.36Å; S7-L77 VanDerWaalsContact CB-O 3.25Å; S7-L77 WeakPolarHBondContact CB-O 3.23Å
8T98.6Very high96.5Very high3 Ų370.2 Ų70.22%0.01835%0.351CS..EExtended strand (participates in β ladder)trans-143.4148.3167.7-167.80000109.1L12 P16 P53 T76 L77 W79T8-L12 HydrophobicContact CG2-CD2 4.21Å; T8-P16 PolarHBondContact OG1-O 3.36Å; T8-P53 HydrophobicContact CG2-CB 4.17Å; T8-P53 HydrophobicContact CG2-CG 3.67Å; T8-T76 WeakPolarHBondContact O-CA 3.25Å; T8-L77 PolarHBondContact N-O 2.82Å; T8-L77 PolarHBondContact O-N 3.19Å; T8-W79 HydrophobicContact CG2-CH2 4.25Å; T8-W79 HydrophobicContact CG2-CZ3 4.15Å
9Q98Very high96.6Very high136 Ų13666.5 Ų66.564%0.63633%0.333SS*.EExtended strand (participates in β ladder)trans-78.7160166.3-69.2-177.4-5.200109.3R11 Q75Q9-R11 PolarHBondContact O-N 2.65Å; Q9-Q75 CarbonylContact C-O 3.55Å; Q9-Q75 WeakPolarHBondContact CA-O 3.42Å
10I92.9Very high96.7Very high101 Ų10163.9 Ų63.952%0.51832%0.323SS..SBendtrans-56.1140.6173.456.6149.3000110.6Q75I10-Q75 HydrophobicContact CG1-CB 4.13Å; I10-Q75 PolarHBondContact N-O 3.05Å
11R95.5Very high96.8Very high184 Ų18464.9 Ų64.969%0.69433%0.33SS*.PPolyproline II helixcis-100.4152.37.6-52-170.4173.7-148.8-0.2113.3Q9 E13 T14Q9-R11 PolarHBondContact O-N 2.65Å; R11-E13 WeakPolarHBondContact CB-OE2 3.31Å; R11-E13 PolarHBondContact O-N 3.07Å; R11-T14 PolarHBondContact O-N 3.33Å
12L95.6Very high97.4Very high74 Ų7464 Ų6439%0.38732%0.324SS..THydrogen-bonded Turntrans-59-27.5-177.6-84.9173.9000115T8 T14 P53 L77 W79T8-L12 HydrophobicContact CG2-CD2 4.21Å; L12-T14 PolarHBondContact O-N 3.44Å; L12-P53 HydrophobicContact CD2-CG 3.9Å; L12-P53 VanDerWaalsContact O-CD 3.31Å; L12-P53 WeakPolarHBondContact O-CD 3.43Å; L12-P53 WeakPolarHBondContact O-CG 3.36Å; L12-L77 HydrophobicContact CD1-CD1 3.66Å; L12-L77 HydrophobicContact CD2-CD1 3.35Å; L12-L77 HydrophobicContact CG-CD1 3.42Å; L12-L77 VanDerWaalsContact CG-CD1 3.42Å; L12-W79 HydrophobicContact CD2-CH2 3.43Å; L12-W79 VanDerWaalsContact CD2-CH2 3.43Å; L12-W79 HydrophobicContact CD2-CZ2 3.85Å
13E96.8Very high97.5Very high148 Ų14871 Ų7169%0.69235%0.347SS*.THydrogen-bonded Turntrans-78.5-9.1-171.2-56.982179.300112.8R11R11-E13 WeakPolarHBondContact CB-OE2 3.31Å; R11-E13 PolarHBondContact O-N 3.07Å
14T97.2Very high97.5Very high82 Ų8265.1 Ų65.150%0.50333%0.325SS..SBendtrans-134.1159.3-178.3-176.70000111.3R11 L12R11-T14 PolarHBondContact O-N 3.33Å; L12-T14 PolarHBondContact O-N 3.44Å
15G95.9Very high97.5Very high16 Ų1667.5 Ų67.517%0.16534%0.338CS..  trans-78.9-177.1164.400000112.5D50G15-D50 WeakPolarHBondContact CA-O 3.42Å
16P98Very high97.4Very high74 Ų7465.8 Ų65.848%0.48133%0.333SS..  cis-77.3152.36.830.9-35000113.3T8 V49T8-P16 PolarHBondContact OG1-O 3.36Å; P16-V49 CarbonylContact C-O 3.57Å; P16-V49 VanDerWaalsContact CA-O 3.25Å; P16-V49 WeakPolarHBondContact CA-O 3.21Å
17T98.8Very high97.4Very high0 Ų069 Ų690%036%0.36CS..EExtended strand (participates in β ladder)trans-111.9124.4171.5-58.30000109.2V6 S7 V19 H48 V49 D51 P53 V56V6-T17 HydrophobicContact CG1-CG2 3.3Å; S7-T17 CarbonylContact O-C 3.58Å; S7-T17 WeakPolarHBondContact O-CA 3.44Å; S7-T17 WeakPolarHBondContact O-CG2 3.34Å; T17-V19 HydrophobicContact CG2-CG1 4.05Å; T17-H48 CarbonylContact O-C 3.55Å; T17-H48 VanDerWaalsContact O-CA 3.26Å; T17-H48 WeakPolarHBondContact O-CA 3.23Å; T17-V49 PolarHBondContact N-O 3.41Å; T17-V49 PolarHBondContact O-N 2.65Å; T17-D51 WeakPolarHBondContact CB-O 3.48Å; T17-D51 PolarHBondContact OG1-O 3Å; T17-P53 HydrophobicContact CG2-CB 4.35Å; T17-P53 WeakPolarHBondContact OG1-CD 3.36Å; T17-P53 VanDerWaalsContact OG1-N 3.11Å; T17-V56 HydrophobicContact CG2-CB 4.22Å; T17-V56 HydrophobicContact CG2-CG1 4.34Å; T17-V56 HydrophobicContact CG2-CG2 3.86Å
18M98.7Very high97.4Very high33 Ų3368.6 Ų68.616%0.16336%0.355CS..EExtended strand (participates in β ladder)trans-78.8129.9172.3-52.7-55.8-65.500108.9V6 S7 E46 Y47 H48V6-M18 CarbonylContact C-O 3.51Å; V6-M18 WeakPolarHBondContact CA-O 3.31Å; S7-M18 PolarHBondContact N-O 3.3Å; S7-M18 PolarHBondContact O-N 3.44Å; M18-E46 HydrophobicContact CE-CB 3.26Å; M18-E46 VanDerWaalsContact CE-CD 3.43Å; M18-E46 HydrophobicContact CE-CG 3.96Å; M18-E46 VanDerWaalsContact CE-OE2 3.31Å; M18-E46 WeakPolarHBondContact CE-OE2 3.27Å; M18-Y47 WeakPolarHBondContact CA-O 3.48Å; M18-H48 HydrophobicContact CE-CB 4.17Å; M18-H48 HydrophobicContact SD-CB 3.58Å; M18-H48 VanDerWaalsContact SD-CB 3.58Å
19V98.8Very high97.4Very high0 Ų068.6 Ų68.60%036%0.355CS..EExtended strand (participates in β ladder)trans-127.7-4.4-169.7-61.70000114.2T17 M29 L32 A34 Y47 V49 V56T17-V19 HydrophobicContact CG2-CG1 4.05Å; V19-M29 HydrophobicContact CG2-SD 3.91Å; V19-M29 WeakPolarHBondContact O-CE 3.33Å; V19-L32 HydrophobicContact CB-CD1 3.77Å; V19-L32 HydrophobicContact CG1-CD1 4.1Å; V19-L32 HydrophobicContact CG2-CD1 3.95Å; V19-A34 HydrophobicContact CG2-CB 3.65Å; V19-Y47 PolarHBondContact N-O 2.91Å; V19-V49 HydrophobicContact CG1-CG2 4.05Å; V19-V49 HydrophobicContact CG2-CG1 4.47Å; V19-V56 HydrophobicContact CG1-CG1 3.62Å; V19-V56 HydrophobicContact CG1-CG2 4.29Å
20G98.3Very high97.4Very high14 Ų1468 Ų6814%0.14436%0.356CS..EExtended strand (participates in β ladder)trans-177.1162.6178.700000113.8S24 E46 Y47G20-S24 WeakPolarHBondContact CA-OG 3.3Å; G20-E46 WeakPolarHBondContact O-CA 3.29Å; G20-Y47 PolarHBondContact O-N 2.91Å
21D98.2Very high97.7Very high85 Ų8568.3 Ų68.346%0.45535%0.352SS..EExtended strand (participates in β ladder)trans-95-174.6171.258.844.4000111.9Y23 S24 S45 Y47D21-Y23 PolarHBondContact O-N 3.24Å; D21-Y23 VanDerWaalsContact O-N 3.13Å; D21-Y23 WeakPolarHBondContact OD1-CA 3.41Å; D21-Y23 PolarHBondContact OD1-N 3.49Å; D21-S24 PolarHBondContact N-OG 3.03Å; D21-S24 WeakPolarHBondContact O-CB 3.29Å; D21-S24 PolarHBondContact O-N 3.35Å; D21-S24 PolarHBondContact O-OG 3.37Å; D21-S24 PolarHBondContact OD1-N 2.86Å; D21-S24 PolarHBondContact OD1-OG 2.77Å; D21-S24 VanDerWaalsContact OD1-OG 3.07Å; D21-S45 CarbonylContact C-O 3.58Å; D21-Y47 WeakPolarHBondContact O-CD2 3.48Å; D21-Y47 VanDerWaalsContact O-CE2 3.23Å; D21-Y47 WeakPolarHBondContact O-CE2 3.31Å
22E97.3Very high97.8Very high75 Ų7559.7 Ų59.735%0.3532%0.319SS..THydrogen-bonded Turntrans-56.5-28.9-178.4-178.1162.2-172.900114.8K36 S45E22-K36 PolarHBondContact O-NZ 3.34Å; E22-K36 VanDerWaalsContact O-NZ 3.12Å; E22-S45 PolarHBondContact N-O 3.04Å
23Y97.1Very high97.9Very high185 Ų18558.9 Ų58.973%0.72533%0.329SS*.THydrogen-bonded Turntrans-105.75.6-174-52.6-64.5000113M1 D21M1-Y23 VanDerWaalsContact CE-O 3.29Å; M1-Y23 WeakPolarHBondContact CE-O 3.34Å; D21-Y23 PolarHBondContact O-N 3.24Å; D21-Y23 VanDerWaalsContact O-N 3.13Å; D21-Y23 WeakPolarHBondContact OD1-CA 3.41Å; D21-Y23 PolarHBondContact OD1-N 3.49Å
24S97.8Very high98Very high8 Ų852.5 Ų52.56%0.05630%0.301CS..SBendtrans-60142.7177.2-68.60000111.9G20 D21 P26G20-S24 WeakPolarHBondContact CA-OG 3.3Å; D21-S24 PolarHBondContact N-OG 3.03Å; D21-S24 WeakPolarHBondContact O-CB 3.29Å; D21-S24 PolarHBondContact O-N 3.35Å; D21-S24 PolarHBondContact O-OG 3.37Å; D21-S24 PolarHBondContact OD1-N 2.86Å; D21-S24 PolarHBondContact OD1-OG 2.77Å; D21-S24 VanDerWaalsContact OD1-OG 3.07Å; S24-P26 VanDerWaalsContact O-CD 3.25Å; S24-P26 WeakPolarHBondContact O-CD 3.35Å; S24-P26 VanDerWaalsContact O-N 3.11Å
25D97.7Very high98.1Very high57 Ų5754.7 Ų54.731%0.30530%0.301SS..  trans-55.6114.2-175.3-174.5-30.8000110.6M1 A27 I28 M29M1-D25 HydrophobicContact CB-CB 4.41Å; M1-D25 HydrophobicContact SD-CB 4.49Å; D25-A27 PolarHBondContact O-N 3.44Å; D25-A27 VanDerWaalsContact O-N 3.14Å; D25-A27 WeakPolarHBondContact OD1-CB 3.13Å; D25-A27 PolarHBondContact OD1-N 3.36Å; D25-I28 HydrophobicContact CB-CB 4.25Å; D25-I28 HydrophobicContact CB-CD1 3.86Å; D25-I28 HydrophobicContact CB-CG1 3.91Å; D25-I28 PolarHBondContact O-N 2.8Å; D25-M29 WeakPolarHBondContact O-CG 3.11Å; D25-M29 PolarHBondContact O-N 2.87Å
26P97.7Very high98.2Very high78 Ų7858.3 Ų58.351%0.50631%0.312SS..Hα-helixtrans-59.2-29.3-175.9-25.734.9000113.5S24 M29 N30S24-P26 VanDerWaalsContact O-CD 3.25Å; S24-P26 WeakPolarHBondContact O-CD 3.35Å; S24-P26 VanDerWaalsContact O-N 3.11Å; P26-M29 PolarHBondContact O-N 2.88Å; P26-N30 VanDerWaalsContact O-CB 3.25Å; P26-N30 WeakPolarHBondContact O-CB 3.31Å; P26-N30 PolarHBondContact O-N 2.81Å; P26-N30 PolarHBondContact O-ND2 3.4Å
27A97.8Very high98.2Very high68 Ų6857.1 Ų57.156%0.56230%0.303SS*.Hα-helixtrans-68-40.2177.800000111.3D25 Y31D25-A27 PolarHBondContact O-N 3.44Å; D25-A27 VanDerWaalsContact O-N 3.14Å; D25-A27 WeakPolarHBondContact OD1-CB 3.13Å; D25-A27 PolarHBondContact OD1-N 3.36Å; A27-Y31 WeakPolarHBondContact O-CB 3.27Å; A27-Y31 PolarHBondContact O-N 3.33Å
28I98.1Very high98.1Very high20 Ų2061 Ų6110%0.10333%0.327CS..Hα-helixtrans-67.7-45.4175.3-57.2-179.9000109.9D25 N30 Y31 L32 L60 I63 F65D25-I28 HydrophobicContact CB-CB 4.25Å; D25-I28 HydrophobicContact CB-CD1 3.86Å; D25-I28 HydrophobicContact CB-CG1 3.91Å; D25-I28 PolarHBondContact O-N 2.8Å; I28-N30 VanDerWaalsContact C-N 3.33Å; I28-N30 PolarHBondContact O-N 2.95Å; I28-Y31 WeakPolarHBondContact O-CB 3.44Å; I28-Y31 PolarHBondContact O-N 2.93Å; I28-L32 HydrophobicContact CG2-CD1 4.23Å; I28-L32 WeakPolarHBondContact O-CG 3.49Å; I28-L32 PolarHBondContact O-N 3.19Å; I28-L60 HydrophobicContact CG2-CD2 4.06Å; I28-I63 HydrophobicContact CG1-CD1 4.48Å; I28-I63 HydrophobicContact CG2-CD1 4.13Å; I28-F65 HydrophobicContact CD1-CE2 3.97Å; I28-F65 HydrophobicContact CD1-CZ 3.85Å
29M98.6Very high97.9Very high2 Ų264.5 Ų64.51%0.0134%0.344CS..Hα-helixtrans-61.6-42179.8-61.4-5610100111.7V19 D25 P26 L32 G33 A34 Y47V19-M29 HydrophobicContact CG2-SD 3.91Å; V19-M29 WeakPolarHBondContact O-CE 3.33Å; D25-M29 WeakPolarHBondContact O-CG 3.11Å; D25-M29 PolarHBondContact O-N 2.87Å; P26-M29 PolarHBondContact O-N 2.88Å; M29-L32 HydrophobicContact CE-CD1 4.26Å; M29-L32 PolarHBondContact O-N 3.38Å; M29-G33 PolarHBondContact O-N 3.1Å; M29-A34 HydrophobicContact CB-CB 4.35Å; M29-A34 WeakPolarHBondContact O-CB 3.44Å; M29-A34 PolarHBondContact O-N 3.3Å; M29-Y47 HydrophobicContact CB-CD1 3.79Å; M29-Y47 HydrophobicContact CB-CE1 3.83Å; M29-Y47 HydrophobicContact CB-CG 4.19Å; M29-Y47 HydrophobicContact CG-CD1 3.8Å; M29-Y47 HydrophobicContact CG-CD2 3.75Å; M29-Y47 HydrophobicContact CG-CE1 3.93Å; M29-Y47 HydrophobicContact CG-CE2 3.88Å; M29-Y47 HydrophobicContact CG-CG 3.7Å; M29-Y47 VanDerWaalsContact SD-CB 3.52Å; M29-Y47 HydrophobicContact SD-CD1 4.16Å; M29-Y47 HydrophobicContact SD-CD2 3.78Å; M29-Y47 HydrophobicContact SD-CE2 4.49Å; M29-Y47 HydrophobicContact SD-CG 3.57Å; M29-Y47 VanDerWaalsContact SD-CG 3.57Å
30N98.4Very high97.7Very high124 Ų12473.3 Ų73.366%0.66339%0.39SS*.Hα-helixtrans-64.9-42.3175-73.9-23000112.1P26 I28 L32 G33P26-N30 VanDerWaalsContact O-CB 3.25Å; P26-N30 WeakPolarHBondContact O-CB 3.31Å; P26-N30 PolarHBondContact O-N 2.81Å; P26-N30 PolarHBondContact O-ND2 3.4Å; I28-N30 VanDerWaalsContact C-N 3.33Å; I28-N30 PolarHBondContact O-N 2.95Å; N30-L32 VanDerWaalsContact C-N 3.29Å; N30-L32 PolarHBondContact O-N 2.79Å; N30-G33 PolarHBondContact O-N 2.95Å
31Y98.6Very high97.6Very high107 Ų10776.2 Ų76.242%0.4242%0.421SS..Hα-helixtrans-60-38.9176.1171.8-100.1000112.4A27 I28 G33 K59 I63A27-Y31 WeakPolarHBondContact O-CB 3.27Å; A27-Y31 PolarHBondContact O-N 3.33Å; I28-Y31 WeakPolarHBondContact O-CB 3.44Å; I28-Y31 PolarHBondContact O-N 2.93Å; Y31-G33 PolarHBondContact O-N 3.1Å; Y31-K59 HydrophobicContact CE1-CB 3.99Å; Y31-K59 WeakPolarHBondContact CE1-O 3.48Å; Y31-I63 HydrophobicContact CD1-CD1 4.12Å; Y31-I63 HydrophobicContact CD1-CG2 4.12Å; Y31-I63 HydrophobicContact CE1-CD1 4.34Å; Y31-I63 HydrophobicContact CE1-CG2 3.65Å; Y31-I63 HydrophobicContact CE2-CG2 4.18Å
32L98.6Very high97.5Very high3 Ų374.9 Ų74.92%0.01641%0.413CS..Hα-helixtrans-71.6-18.6176.1-66.2175.9000113V19 I28 M29 N30 V49 V56 K59 L60V19-L32 HydrophobicContact CB-CD1 3.77Å; V19-L32 HydrophobicContact CG1-CD1 4.1Å; V19-L32 HydrophobicContact CG2-CD1 3.95Å; I28-L32 HydrophobicContact CG2-CD1 4.23Å; I28-L32 WeakPolarHBondContact O-CG 3.49Å; I28-L32 PolarHBondContact O-N 3.19Å; M29-L32 HydrophobicContact CE-CD1 4.26Å; M29-L32 PolarHBondContact O-N 3.38Å; N30-L32 VanDerWaalsContact C-N 3.29Å; N30-L32 PolarHBondContact O-N 2.79Å; L32-V49 HydrophobicContact CB-CG1 4.24Å; L32-V49 WeakPolarHBondContact O-CG1 3.48Å; L32-V56 HydrophobicContact CD2-CG1 4.44Å; L32-K59 HydrophobicContact CD2-CB 3.74Å; L32-K59 HydrophobicContact CD2-CD 4.06Å; L32-K59 PolarHBondContact O-NZ 2.86Å; L32-L60 HydrophobicContact CD1-CD2 4.14Å; L32-L60 HydrophobicContact CD2-CD2 4.17Å; L32-L60 HydrophobicContact CD2-CG 4.19Å
33G98.4Very high97.5Very high57 Ų5778.5 Ų78.559%0.58844%0.435SS*.THydrogen-bonded Turntrans76.829.2-171.900000112.6M29 N30 Y31M29-G33 PolarHBondContact O-N 3.1Å; N30-G33 PolarHBondContact O-N 2.95Å; Y31-G33 PolarHBondContact O-N 3.1Å
34A98.7Very high97.4Very high14 Ų1474 Ų7412%0.11642%0.419CS..  trans-78.7146.4-172.600000113V19 M29 Y47 H48 V49V19-A34 HydrophobicContact CG2-CB 3.65Å; M29-A34 HydrophobicContact CB-CB 4.35Å; M29-A34 WeakPolarHBondContact O-CB 3.44Å; M29-A34 PolarHBondContact O-N 3.3Å; A34-Y47 HydrophobicContact CB-CD1 4.11Å; A34-H48 CarbonylContact C-O 3.53Å; A34-H48 VanDerWaalsContact CA-O 3.3Å; A34-H48 WeakPolarHBondContact CA-O 3.44Å; A34-V49 HydrophobicContact CB-CG1 3.74Å
35R98.4Very high97.4Very high129 Ų12974.3 Ų74.349%0.48742%0.422SS..EExtended strand (participates in β ladder)trans-104.3133.5172.7-64.6-177.1-62.2-140.9-10110Y47 H48 D50R35-Y47 WeakPolarHBondContact O-CA 3.31Å; R35-H48 PolarHBondContact N-O 2.85Å; R35-H48 PolarHBondContact NH2-NE2 2.97Å; R35-H48 PolarHBondContact O-N 2.88Å; R35-D50 IonicContact CZ-OD2 3.71Å; R35-D50 IonicContact NH1-OD2 3.79Å; R35-D50 IonicContact NH2-OD1 2.93Å; R35-D50 PolarHBondContact NH2-OD1 3.4Å; R35-D50 IonicContact NH2-OD2 3.03Å; R35-D50 PolarHBondContact NH2-OD2 3.39Å
36K98.3Very high97.4Very high91 Ų9174 Ų7440%0.39642%0.419SS..EExtended strand (participates in β ladder)trans-82127171.8-162.1175.1-169.4166.80109.6E22 E46 Y47E22-K36 PolarHBondContact O-NZ 3.34Å; E22-K36 VanDerWaalsContact O-NZ 3.12Å; K36-E46 CarbonylContact C-O 3.52Å; K36-E46 WeakPolarHBondContact CA-O 3.38Å; K36-Y47 HydrophobicContact CB-CD1 3.9Å; K36-Y47 HydrophobicContact CB-CE1 3.58Å; K36-Y47 HydrophobicContact CD-CE1 4.23Å; K36-Y47 HydrophobicContact CD-CE2 4.12Å; K36-Y47 HydrophobicContact CG-CD1 4.4Å; K36-Y47 HydrophobicContact CG-CE1 4.05Å; K36-Y47 HydrophobicContact CG-CE2 4.2Å
37T97.3Very high97.5Very high49 Ų4971.7 Ų71.730%0.30140%0.4SS..EExtended strand (participates in β ladder)trans-136146.7177.446.90000111.4S45 E46 H48T37-S45 WeakPolarHBondContact O-CA 3.13Å; T37-E46 PolarHBondContact N-O 3.15Å; T37-E46 PolarHBondContact O-N 2.87Å; T37-H48 PolarHBondContact OG1-CE1 2.81Å; T37-H48 PolarHBondContact OG1-ND1 2.82Å
38T97.3Very high97.5Very high83 Ų8369.8 Ų69.851%0.50938%0.38SS..  trans-114.1109.7168.5-48.20000106.7S45T38-S45 PolarHBondContact OG1-OG 3.06Å
39M94.1Very high97.5Very high105 Ų10569.1 Ų69.152%0.51738%0.376SS..  trans-69.1147.1175.6-61.2-165.5-150.400110.1G41 N42M39-G41 PolarHBondContact O-N 3.45Å; M39-N42 WeakPolarHBondContact O-CB 3.41Å; M39-N42 PolarHBondContact O-N 3.13Å
40L95Very high97.5Very high185 Ų18574.2 Ų74.297%0.96940%0.403SS*.THydrogen-bonded Turntrans-57.7125.2176.1-178.967.3000109.9
41G96.4Very high97.5Very high76 Ų7670.6 Ų70.678%0.78438%0.384SS*.THydrogen-bonded Turntrans98.5-15.4-177.100000114.3M39M39-G41 PolarHBondContact O-N 3.45Å
42N95.4Very high97.5Very high56 Ų5666.4 Ų66.430%0.29937%0.37SS..  trans-86.3142.5173.2-67.5-4000110.6M39 F44M39-N42 WeakPolarHBondContact O-CB 3.41Å; M39-N42 PolarHBondContact O-N 3.13Å; N42-F44 HydrophobicContact CB-CD1 4.13Å; N42-F44 HydrophobicContact CB-CE1 3.96Å; N42-F44 HydrophobicContact CB-CE2 4.47Å; N42-F44 HydrophobicContact CB-CG 4.46Å; N42-F44 HydrophobicContact CB-CZ 4.14Å; N42-F44 WeakPolarHBondContact ND2-CZ 3.25Å
43N96.8Very high97.5Very high152 Ų15266.4 Ų66.481%0.81337%0.371SS*.SBendtrans-97.911.8169.466.9-24.6000112.5
44F96Very high97.5Very high89 Ų8970.5 Ų70.539%0.3937%0.368SS..SBendtrans-133.2154.9-18059.8-90.7000110.2N42 E46N42-F44 HydrophobicContact CB-CD1 4.13Å; N42-F44 HydrophobicContact CB-CE1 3.96Å; N42-F44 HydrophobicContact CB-CE2 4.47Å; N42-F44 HydrophobicContact CB-CG 4.46Å; N42-F44 HydrophobicContact CB-CZ 4.14Å; N42-F44 WeakPolarHBondContact ND2-CZ 3.25Å; F44-E46 HydrophobicContact CD2-CG 3.68Å; F44-E46 VanDerWaalsContact CE2-CD 3.48Å; F44-E46 HydrophobicContact CE2-CG 3.65Å
45S97.8Very high97.5Very high16 Ų1672.8 Ų72.811%0.11238%0.378CS..  trans-104.4150.5174.7-57.50000111.4D21 E22 T37 T38D21-S45 CarbonylContact C-O 3.58Å; E22-S45 PolarHBondContact N-O 3.04Å; T37-S45 WeakPolarHBondContact O-CA 3.13Å; T38-S45 PolarHBondContact OG1-OG 3.06Å
46E97.9Very high97.5Very high51 Ų5166.7 Ų66.724%0.23836%0.356CS..EExtended strand (participates in β ladder)trans-133.6151.9178.1-55.9176.5117.200110.6M18 G20 K36 T37 F44M18-E46 HydrophobicContact CE-CB 3.26Å; M18-E46 VanDerWaalsContact CE-CD 3.43Å; M18-E46 HydrophobicContact CE-CG 3.96Å; M18-E46 VanDerWaalsContact CE-OE2 3.31Å; M18-E46 WeakPolarHBondContact CE-OE2 3.27Å; G20-E46 WeakPolarHBondContact O-CA 3.29Å; K36-E46 CarbonylContact C-O 3.52Å; K36-E46 WeakPolarHBondContact CA-O 3.38Å; T37-E46 PolarHBondContact N-O 3.15Å; T37-E46 PolarHBondContact O-N 2.87Å; F44-E46 HydrophobicContact CD2-CG 3.68Å; F44-E46 VanDerWaalsContact CE2-CD 3.48Å; F44-E46 HydrophobicContact CE2-CG 3.65Å
47Y98.8Very high97.6Very high29 Ų2963.8 Ų63.811%0.11434%0.344CS..EExtended strand (participates in β ladder)trans-98.2133.1171.6-71.1-88.4000110.4M18 V19 G20 D21 M29 A34 R35 K36M18-Y47 WeakPolarHBondContact CA-O 3.48Å; V19-Y47 PolarHBondContact N-O 2.91Å; G20-Y47 PolarHBondContact O-N 2.91Å; D21-Y47 WeakPolarHBondContact O-CD2 3.48Å; D21-Y47 VanDerWaalsContact O-CE2 3.23Å; D21-Y47 WeakPolarHBondContact O-CE2 3.31Å; M29-Y47 HydrophobicContact CB-CD1 3.79Å; M29-Y47 HydrophobicContact CB-CE1 3.83Å; M29-Y47 HydrophobicContact CB-CG 4.19Å; M29-Y47 HydrophobicContact CG-CD1 3.8Å; M29-Y47 HydrophobicContact CG-CD2 3.75Å; M29-Y47 HydrophobicContact CG-CE1 3.93Å; M29-Y47 HydrophobicContact CG-CE2 3.88Å; M29-Y47 HydrophobicContact CG-CG 3.7Å; M29-Y47 VanDerWaalsContact SD-CB 3.52Å; M29-Y47 HydrophobicContact SD-CD1 4.16Å; M29-Y47 HydrophobicContact SD-CD2 3.78Å; M29-Y47 HydrophobicContact SD-CE2 4.49Å; M29-Y47 HydrophobicContact SD-CG 3.57Å; M29-Y47 VanDerWaalsContact SD-CG 3.57Å; A34-Y47 HydrophobicContact CB-CD1 4.11Å; R35-Y47 WeakPolarHBondContact O-CA 3.31Å; K36-Y47 HydrophobicContact CB-CD1 3.9Å; K36-Y47 HydrophobicContact CB-CE1 3.58Å; K36-Y47 HydrophobicContact CD-CE1 4.23Å; K36-Y47 HydrophobicContact CD-CE2 4.12Å; K36-Y47 HydrophobicContact CG-CD1 4.4Å; K36-Y47 HydrophobicContact CG-CE1 4.05Å; K36-Y47 HydrophobicContact CG-CE2 4.2Å
48H98.6Very high97.6Very high28 Ų2864.8 Ų64.813%0.1335%0.347CS..EExtended strand (participates in β ladder)trans-135.2157.317472.8-91.2000112T17 M18 A34 R35 T37T17-H48 CarbonylContact O-C 3.55Å; T17-H48 VanDerWaalsContact O-CA 3.26Å; T17-H48 WeakPolarHBondContact O-CA 3.23Å; M18-H48 HydrophobicContact CE-CB 4.17Å; M18-H48 HydrophobicContact SD-CB 3.58Å; M18-H48 VanDerWaalsContact SD-CB 3.58Å; A34-H48 CarbonylContact C-O 3.53Å; A34-H48 VanDerWaalsContact CA-O 3.3Å; A34-H48 WeakPolarHBondContact CA-O 3.44Å; R35-H48 PolarHBondContact N-O 2.85Å; R35-H48 PolarHBondContact NH2-NE2 2.97Å; R35-H48 PolarHBondContact O-N 2.88Å; T37-H48 PolarHBondContact OG1-CE1 2.81Å; T37-H48 PolarHBondContact OG1-ND1 2.82Å
49V98.8Very high97.7Very high6 Ų663.5 Ų63.54%0.03634%0.335CS..EExtended strand (participates in β ladder)trans-125.1155.3170-64.60000109.9P16 T17 V19 L32 A34 D51 V56P16-V49 CarbonylContact C-O 3.57Å; P16-V49 VanDerWaalsContact CA-O 3.25Å; P16-V49 WeakPolarHBondContact CA-O 3.21Å; T17-V49 PolarHBondContact N-O 3.41Å; T17-V49 PolarHBondContact O-N 2.65Å; V19-V49 HydrophobicContact CG1-CG2 4.05Å; V19-V49 HydrophobicContact CG2-CG1 4.47Å; L32-V49 HydrophobicContact CB-CG1 4.24Å; L32-V49 WeakPolarHBondContact O-CG1 3.48Å; A34-V49 HydrophobicContact CB-CG1 3.74Å; V49-D51 HydrophobicContact CG2-CB 4.03Å; V49-D51 PolarHBondContact O-N 2.69Å; V49-V56 HydrophobicContact CG2-CG2 3.46Å; V49-V56 VanDerWaalsContact CG2-CG2 3.46Å
50D98.4Very high97.9Very high108 Ų10858.5 Ų58.558%0.57831%0.31SS*.SBendtrans-78.9-11177.3-62.4-31.2000112.4G15 R35G15-D50 WeakPolarHBondContact CA-O 3.42Å; R35-D50 IonicContact CZ-OD2 3.71Å; R35-D50 IonicContact NH1-OD2 3.79Å; R35-D50 IonicContact NH2-OD1 2.93Å; R35-D50 PolarHBondContact NH2-OD1 3.4Å; R35-D50 IonicContact NH2-OD2 3.03Å; R35-D50 PolarHBondContact NH2-OD2 3.39Å
51D98.6Very high98.1Very high49 Ų4955.7 Ų55.726%0.26229%0.292SS..SBendtrans-66.1148.2177.2-70.7-37.1000112.5T17 V49 L55 V56 K59T17-D51 WeakPolarHBondContact CB-O 3.48Å; T17-D51 PolarHBondContact OG1-O 3Å; V49-D51 HydrophobicContact CG2-CB 4.03Å; V49-D51 PolarHBondContact O-N 2.69Å; D51-L55 HydrophobicContact CB-CB 4.08Å; D51-L55 HydrophobicContact CB-CD1 4.28Å; D51-V56 HydrophobicContact CB-CG2 4.14Å; D51-K59 IonicContact OD2-NZ 2.65Å; D51-K59 PolarHBondContact OD2-NZ 3.07Å
52S98.6Very high98.2Very high18 Ų1859.3 Ų59.313%0.12629%0.286CS..  trans-61.3152.8167.269.40000111.7R54 L55 V56S52-R54 PolarHBondContact O-N 3.41Å; S52-R54 VanDerWaalsContact O-N 3.13Å; S52-L55 PolarHBondContact O-N 2.99Å; S52-V56 PolarHBondContact O-N 2.8Å
53P98.6Very high98.2Very high3 Ų358.8 Ų58.82%0.01928%0.283CS..Hα-helixtrans-55.5-35.6179.223.9-38.3000112.4T8 L12 T17 L55 V56 L57 W79T8-P53 HydrophobicContact CG2-CB 4.17Å; T8-P53 HydrophobicContact CG2-CG 3.67Å; L12-P53 HydrophobicContact CD2-CG 3.9Å; L12-P53 VanDerWaalsContact O-CD 3.31Å; L12-P53 WeakPolarHBondContact O-CD 3.43Å; L12-P53 WeakPolarHBondContact O-CG 3.36Å; T17-P53 HydrophobicContact CG2-CB 4.35Å; T17-P53 WeakPolarHBondContact OG1-CD 3.36Å; T17-P53 VanDerWaalsContact OG1-N 3.11Å; P53-L55 VanDerWaalsContact C-N 3.34Å; P53-L55 PolarHBondContact O-N 3.43Å; P53-V56 WeakPolarHBondContact O-CB 3.38Å; P53-V56 PolarHBondContact O-N 3.02Å; P53-V56 VanDerWaalsContact O-N 3.1Å; P53-L57 VanDerWaalsContact O-CG 3.27Å; P53-L57 WeakPolarHBondContact O-CG 3.49Å; P53-L57 PolarHBondContact O-N 3.36Å; P53-W79 HydrophobicContact CB-CE3 4.44Å; P53-W79 HydrophobicContact CB-CH2 3.83Å; P53-W79 HydrophobicContact CB-CZ3 3.79Å; P53-W79 HydrophobicContact CG-CH2 4.04Å; P53-W79 HydrophobicContact CG-CZ3 4.4Å
54R98.6Very high98.3Very high144 Ų14453.7 Ų53.754%0.54327%0.266SS..Hα-helixtrans-55.7-46.5177.5-168.5-161.167.670.13112.3S52 V56 L57 D58S52-R54 PolarHBondContact O-N 3.41Å; S52-R54 VanDerWaalsContact O-N 3.13Å; R54-V56 VanDerWaalsContact C-N 3.33Å; R54-L57 PolarHBondContact O-N 3.21Å; R54-D58 IonicContact CZ-OD2 3.92Å; R54-D58 IonicContact NH1-OD1 2.65Å; R54-D58 IonicContact NH1-OD2 3.67Å; R54-D58 PolarHBondContact NH1-OD2 2.97Å; R54-D58 VanDerWaalsContact O-CG 3.28Å; R54-D58 PolarHBondContact O-N 3.04Å
55L98.7Very high98.4Very high62 Ų6249.7 Ų49.733%0.32525%0.249SC..Hα-helixtrans-67.4-34.6178.6-74.1172.5000112.1D51 S52 P53 K59D51-L55 HydrophobicContact CB-CB 4.08Å; D51-L55 HydrophobicContact CB-CD1 4.28Å; S52-L55 PolarHBondContact O-N 2.99Å; P53-L55 VanDerWaalsContact C-N 3.34Å; P53-L55 PolarHBondContact O-N 3.43Å; L55-K59 WeakPolarHBondContact O-CG 3.42Å; L55-K59 PolarHBondContact O-N 2.87Å; L55-K59 VanDerWaalsContact O-N 3.1Å
56V98.8Very high98.4Very high1 Ų155.4 Ų55.41%0.00627%0.268CS..Hα-helixtrans-67.3-46.5176176.50000111.1V6 T17 V19 L32 V49 D51 S52 P53 R54 D58 K59 L60V6-V56 HydrophobicContact CG1-CG1 3.96Å; V6-V56 HydrophobicContact CG2-CG1 4.28Å; T17-V56 HydrophobicContact CG2-CB 4.22Å; T17-V56 HydrophobicContact CG2-CG1 4.34Å; T17-V56 HydrophobicContact CG2-CG2 3.86Å; V19-V56 HydrophobicContact CG1-CG1 3.62Å; V19-V56 HydrophobicContact CG1-CG2 4.29Å; L32-V56 HydrophobicContact CD2-CG1 4.44Å; V49-V56 HydrophobicContact CG2-CG2 3.46Å; V49-V56 VanDerWaalsContact CG2-CG2 3.46Å; D51-V56 HydrophobicContact CB-CG2 4.14Å; S52-V56 PolarHBondContact O-N 2.8Å; P53-V56 WeakPolarHBondContact O-CB 3.38Å; P53-V56 PolarHBondContact O-N 3.02Å; P53-V56 VanDerWaalsContact O-N 3.1Å; R54-V56 VanDerWaalsContact C-N 3.33Å; V56-D58 VanDerWaalsContact C-N 3.32Å; V56-D58 PolarHBondContact O-N 2.93Å; V56-K59 WeakPolarHBondContact O-CB 3.48Å; V56-K59 PolarHBondContact O-N 3.3Å; V56-K59 VanDerWaalsContact O-N 3.15Å; V56-L60 HydrophobicContact CG1-CD1 3.96Å; V56-L60 HydrophobicContact CG1-CG 4.42Å; V56-L60 WeakPolarHBondContact O-CG 3.33Å; V56-L60 PolarHBondContact O-N 2.93Å
57L98.8Very high98.4Very high29 Ų2956.5 Ų56.515%0.15228%0.278CS..Hα-helixtrans-60.8-41.8177.5-62.5177.7000111P53 R54 K59 L60 E61 V67 W79 M81P53-L57 VanDerWaalsContact O-CG 3.27Å; P53-L57 WeakPolarHBondContact O-CG 3.49Å; P53-L57 PolarHBondContact O-N 3.36Å; R54-L57 PolarHBondContact O-N 3.21Å; L57-K59 VanDerWaalsContact C-N 3.34Å; L57-K59 PolarHBondContact O-N 2.77Å; L57-L60 PolarHBondContact O-N 2.87Å; L57-E61 WeakPolarHBondContact O-CB 3.17Å; L57-E61 PolarHBondContact O-N 3.02Å; L57-V67 HydrophobicContact CD2-CG2 4.37Å; L57-W79 HydrophobicContact CD1-CD2 4.2Å; L57-W79 HydrophobicContact CD1-CG 4.08Å; L57-W79 HydrophobicContact CD2-CB 4.04Å; L57-W79 HydrophobicContact CD2-CG 4.06Å; L57-M81 HydrophobicContact CD2-CE 4.17Å; L57-M81 HydrophobicContact CD2-CG 4.14Å; L57-M81 HydrophobicContact CD2-SD 3.31Å; L57-M81 WeakPolarHBondContact CD2-SD 3.45Å
58D98.8Very high98.4Very high70 Ų7058.6 Ų58.637%0.37429%0.294SS..Hα-helixtrans-59.8-41.5173.9-69.9-8.4000112.3R54 V56 K62R54-D58 IonicContact CZ-OD2 3.92Å; R54-D58 IonicContact NH1-OD1 2.65Å; R54-D58 IonicContact NH1-OD2 3.67Å; R54-D58 PolarHBondContact NH1-OD2 2.97Å; R54-D58 VanDerWaalsContact O-CG 3.28Å; R54-D58 PolarHBondContact O-N 3.04Å; V56-D58 VanDerWaalsContact C-N 3.32Å; V56-D58 PolarHBondContact O-N 2.93Å; D58-K62 WeakPolarHBondContact O-CG 3.35Å; D58-K62 PolarHBondContact O-N 3.14Å
59K98.8Very high98.4Very high57 Ų5761.2 Ų61.225%0.24831%0.312CS..Hα-helixtrans-66.4-43.7177.3-75.9173.4176.1178.50111.2Y31 L32 D51 L55 V56 L57 E61 K62Y31-K59 HydrophobicContact CE1-CB 3.99Å; Y31-K59 WeakPolarHBondContact CE1-O 3.48Å; L32-K59 HydrophobicContact CD2-CB 3.74Å; L32-K59 HydrophobicContact CD2-CD 4.06Å; L32-K59 PolarHBondContact O-NZ 2.86Å; D51-K59 IonicContact OD2-NZ 2.65Å; D51-K59 PolarHBondContact OD2-NZ 3.07Å; L55-K59 WeakPolarHBondContact O-CG 3.42Å; L55-K59 PolarHBondContact O-N 2.87Å; L55-K59 VanDerWaalsContact O-N 3.1Å; V56-K59 WeakPolarHBondContact O-CB 3.48Å; V56-K59 PolarHBondContact O-N 3.3Å; V56-K59 VanDerWaalsContact O-N 3.15Å; L57-K59 VanDerWaalsContact C-N 3.34Å; L57-K59 PolarHBondContact O-N 2.77Å; K59-E61 VanDerWaalsContact C-N 3.33Å; K59-K62 PolarHBondContact O-N 3.47Å
60L98.6Very high98.4Very high0 Ų066 Ų660%034%0.335CS..Hα-helixtrans-65.8-36.2179-73.6174.1000111.9V6 I28 L32 V56 L57 K62 I63 G64 F65 M81V6-L60 HydrophobicContact CG2-CD1 3.53Å; I28-L60 HydrophobicContact CG2-CD2 4.06Å; L32-L60 HydrophobicContact CD1-CD2 4.14Å; L32-L60 HydrophobicContact CD2-CD2 4.17Å; L32-L60 HydrophobicContact CD2-CG 4.19Å; V56-L60 HydrophobicContact CG1-CD1 3.96Å; V56-L60 HydrophobicContact CG1-CG 4.42Å; V56-L60 WeakPolarHBondContact O-CG 3.33Å; V56-L60 PolarHBondContact O-N 2.93Å; L57-L60 PolarHBondContact O-N 2.87Å; L60-K62 PolarHBondContact O-N 2.87Å; L60-I63 HydrophobicContact CD2-CD1 4.14Å; L60-I63 WeakPolarHBondContact O-CG1 3.45Å; L60-I63 PolarHBondContact O-N 2.91Å; L60-G64 PolarHBondContact O-N 3.14Å; L60-F65 HydrophobicContact CB-CB 4.07Å; L60-F65 HydrophobicContact CB-CD2 4.36Å; L60-F65 HydrophobicContact CB-CG 4.48Å; L60-F65 HydrophobicContact CD2-CD2 4.01Å; L60-F65 HydrophobicContact CD2-CE2 4.31Å; L60-F65 WeakPolarHBondContact O-CB 3.45Å; L60-F65 PolarHBondContact O-N 3.03Å; L60-M81 HydrophobicContact CB-CE 4.23Å; L60-M81 HydrophobicContact CB-SD 3.79Å; L60-M81 HydrophobicContact CD1-SD 3.48Å; L60-M81 WeakPolarHBondContact CD1-SD 3.34Å; L60-M81 HydrophobicContact CG-SD 4.29Å
61E98.5Very high98.4Very high125 Ų12565 Ų6558%0.58433%0.333SS*.Hα-helixtrans-59.2-44.7174.1-170.6-78.5158.800112L57 K59 I63 G64 F65L57-E61 WeakPolarHBondContact O-CB 3.17Å; L57-E61 PolarHBondContact O-N 3.02Å; K59-E61 VanDerWaalsContact C-N 3.33Å; E61-I63 PolarHBondContact O-N 2.89Å; E61-G64 PolarHBondContact O-N 3.4Å; E61-F65 VanDerWaalsContact CA-O 3.31Å; E61-F65 WeakPolarHBondContact CA-O 3.42Å
62K98.3Very high98.4Very high153 Ų15365 Ų6567%0.66535%0.345SS*.Hα-helixtrans-59.1-23178.5-70.9173.9-176.4178.70114.6D58 K59 L60D58-K62 WeakPolarHBondContact O-CG 3.35Å; D58-K62 PolarHBondContact O-N 3.14Å; K59-K62 PolarHBondContact O-N 3.47Å; L60-K62 PolarHBondContact O-N 2.87Å
63I96.9Very high98.4Very high44 Ų4468.5 Ų68.523%0.22637%0.365CS..THydrogen-bonded Turntrans-104.210.9177.565.9169.4000112.6I28 Y31 L60 E61 F65 K83I28-I63 HydrophobicContact CG1-CD1 4.48Å; I28-I63 HydrophobicContact CG2-CD1 4.13Å; Y31-I63 HydrophobicContact CD1-CD1 4.12Å; Y31-I63 HydrophobicContact CD1-CG2 4.12Å; Y31-I63 HydrophobicContact CE1-CD1 4.34Å; Y31-I63 HydrophobicContact CE1-CG2 3.65Å; Y31-I63 HydrophobicContact CE2-CG2 4.18Å; L60-I63 HydrophobicContact CD2-CD1 4.14Å; L60-I63 WeakPolarHBondContact O-CG1 3.45Å; L60-I63 PolarHBondContact O-N 2.91Å; E61-I63 PolarHBondContact O-N 2.89Å; I63-F65 HydrophobicContact CD1-CD2 4.02Å; I63-F65 HydrophobicContact CD1-CE2 3.85Å; I63-F65 HydrophobicContact CG1-CD2 3.82Å; I63-F65 HydrophobicContact CG1-CE2 4.09Å; I63-K83 WeakPolarHBondContact O-CD 3.29Å; I63-K83 VanDerWaalsContact O-CE 3.23Å; I63-K83 WeakPolarHBondContact O-CE 3.45Å; I63-K83 PolarHBondContact O-NZ 2.94Å
64G97.3Very high98.3Very high45 Ų4572 Ų7246%0.46440%0.401SS..THydrogen-bonded Turntrans99.812168.600000115.8L60 E61L60-G64 PolarHBondContact O-N 3.14Å; E61-G64 PolarHBondContact O-N 3.4Å
65F98.4Very high98.3Very high5 Ų570.9 Ų70.92%0.02240%0.402CS..EExtended strand (participates in β ladder)trans-85.2144172.7-71.6-90.6000111.7V4 I28 L60 E61 I63 M81 Y82 K83V4-F65 HydrophobicContact CB-CE1 4.28Å; V4-F65 HydrophobicContact CG2-CD1 4.4Å; V4-F65 HydrophobicContact CG2-CE1 3.65Å; V4-F65 HydrophobicContact CG2-CZ 3.78Å; I28-F65 HydrophobicContact CD1-CE2 3.97Å; I28-F65 HydrophobicContact CD1-CZ 3.85Å; L60-F65 HydrophobicContact CB-CB 4.07Å; L60-F65 HydrophobicContact CB-CD2 4.36Å; L60-F65 HydrophobicContact CB-CG 4.48Å; L60-F65 HydrophobicContact CD2-CD2 4.01Å; L60-F65 HydrophobicContact CD2-CE2 4.31Å; L60-F65 WeakPolarHBondContact O-CB 3.45Å; L60-F65 PolarHBondContact O-N 3.03Å; E61-F65 VanDerWaalsContact CA-O 3.31Å; E61-F65 WeakPolarHBondContact CA-O 3.42Å; I63-F65 HydrophobicContact CD1-CD2 4.02Å; I63-F65 HydrophobicContact CD1-CE2 3.85Å; I63-F65 HydrophobicContact CG1-CD2 3.82Å; I63-F65 HydrophobicContact CG1-CE2 4.09Å; F65-M81 HydrophobicContact CB-CB 4.19Å; F65-M81 HydrophobicContact CB-CE 3.93Å; F65-M81 HydrophobicContact CB-SD 4.43Å; F65-M81 HydrophobicContact CD1-CB 4.15Å; F65-Y82 CarbonylContact C-O 3.51Å; F65-Y82 WeakPolarHBondContact CA-O 3.38Å; F65-K83 HydrophobicContact CD1-CB 3.52Å; F65-K83 HydrophobicContact CD2-CB 4.09Å; F65-K83 HydrophobicContact CD2-CD 4.31Å; F65-K83 HydrophobicContact CE1-CB 3.51Å; F65-K83 HydrophobicContact CE2-CB 4.09Å; F65-K83 HydrophobicContact CE2-CD 4Å; F65-K83 HydrophobicContact CG-CB 3.8Å; F65-K83 HydrophobicContact CZ-CB 3.8Å; F65-K83 HydrophobicContact CZ-CD 4.23Å
66R98.3Very high98.2Very high137 Ų13769.5 Ų69.552%0.51740%0.396SS..EExtended strand (participates in β ladder)trans-121.9145.9170.653.3176.9165.584.6-3.8110.8V68 M81 Y82R66-V68 PolarHBondContact O-N 3.19Å; R66-M81 CarbonylContact O-C 3.55Å; R66-M81 VanDerWaalsContact O-CA 3.27Å; R66-M81 WeakPolarHBondContact O-CA 3.25Å; R66-Y82 WeakPolarHBondContact CG-O 3.3Å; R66-Y82 VanDerWaalsContact CZ-CD1 3.47Å; R66-Y82 PolarHBondContact N-O 3.18Å; R66-Y82 VanDerWaalsContact NH2-CE1 3.28Å; R66-Y82 PolarHBondContact O-N 2.91Å
67V98.4Very high98.2Very high73 Ų7371.1 Ų71.144%0.44241%0.405SS..EExtended strand (participates in β ladder)trans-65.7126.3170.9179.90000108.6L57 M81L57-V67 HydrophobicContact CD2-CG2 4.37Å; V67-M81 HydrophobicContact CG2-CE 3.8Å
68V98.4Very high98.2Very high74 Ų7471.2 Ų71.245%0.44841%0.407SS..EExtended strand (participates in β ladder)trans-93.5-46.2173.11790000110R66 C80 Y82R66-V68 PolarHBondContact O-N 3.19Å; V68-C80 PolarHBondContact N-O 2.93Å; V68-Y82 VanDerWaalsContact CG2-CB 3.45Å
69T98.6Very high98.2Very high83 Ų8369 Ų6951%0.50939%0.393SS..EExtended strand (participates in β ladder)trans-157.3162.7179.2-171.70000110.8C80T69-C80 HydrophobicContact CG2-CB 3.78Å; T69-C80 PolarHBondContact O-N 3.03Å
70M98.5Very high98.2Very high106 Ų10667.5 Ų67.552%0.52239%0.39SS..EExtended strand (participates in β ladder)trans-134.3140.9175180-163.372.900109V78 W79M70-V78 CarbonylContact C-O 3.6Å; M70-V78 VanDerWaalsContact CA-O 3.29Å; M70-V78 WeakPolarHBondContact CA-O 3.44Å; M70-W79 HydrophobicContact CB-CG 4.49Å; M70-W79 HydrophobicContact CG-CD2 4.3Å; M70-W79 HydrophobicContact CG-CG 4.26Å; M70-W79 HydrophobicContact CG-CZ2 4.35Å; M70-W79 HydrophobicContact SD-CZ2 3.99Å; M70-W79 PolarHBondContact SD-NE1 3.05Å; M70-W79 VanDerWaalsContact SD-NE1 3.44Å
71T98.4Very high98.2Very high86 Ų8667.7 Ų67.753%0.52839%0.39SS..EExtended strand (participates in β ladder)trans-143.1160.2173.9-166.90000112V78T71-V78 HydrophobicContact CG2-CB 4.35Å; T71-V78 PolarHBondContact N-O 3.18Å; T71-V78 PolarHBondContact O-N 2.99Å
72G98.2Very high98.2Very high50 Ų5063.1 Ų63.152%0.51537%0.368SS..EExtended strand (participates in β ladder)trans-110.1137.1170.400000111.2T76G72-T76 CarbonylContact C-O 3.6Å; G72-T76 WeakPolarHBondContact CA-O 3.26Å
73V97.6Very high98.1Very high92 Ų9259.7 Ų59.756%0.55835%0.353SS*.EExtended strand (participates in β ladder)trans-135.3110.3175.659.10000109.7Q75 T76 V78V73-Q75 PolarHBondContact O-N 3.47Å; V73-Q75 VanDerWaalsContact O-N 3.14Å; V73-T76 PolarHBondContact N-O 2.82Å; V73-T76 WeakPolarHBondContact O-CB 3.48Å; V73-T76 PolarHBondContact O-N 3.05Å; V73-V78 HydrophobicContact CG1-CG2 4.26Å
74G97.5Very high97.9Very high75 Ų7564.1 Ų64.177%0.77337%0.373SS*.THydrogen-bonded Turntrans62.2-114.2-173.400000111.7
75Q97.6Very high97.3Very high122 Ų12264 Ų6457%0.5736%0.364SS*.THydrogen-bonded Turntrans-105.812.1176.4-66.1-58.1-77.300112.6Q9 I10 V73Q9-Q75 CarbonylContact C-O 3.55Å; Q9-Q75 WeakPolarHBondContact CA-O 3.42Å; I10-Q75 HydrophobicContact CG1-CB 4.13Å; I10-Q75 PolarHBondContact N-O 3.05Å; V73-Q75 PolarHBondContact O-N 3.47Å; V73-Q75 VanDerWaalsContact O-N 3.14Å
76T98.4Very high95.9Very high32 Ų3271.5 Ų71.520%0.19640%0.403CS..EExtended strand (participates in β ladder)trans-110.9137.5-176.6-53.80000110.4T8 G72 V73 V78T8-T76 WeakPolarHBondContact O-CA 3.25Å; G72-T76 CarbonylContact C-O 3.6Å; G72-T76 WeakPolarHBondContact CA-O 3.26Å; V73-T76 PolarHBondContact N-O 2.82Å; V73-T76 WeakPolarHBondContact O-CB 3.48Å; V73-T76 PolarHBondContact O-N 3.05Å; T76-V78 HydrophobicContact CG2-CG2 4.16Å
77L98.6Very high94.1Very high35 Ų3572.9 Ų72.918%0.18341%0.41CS..EExtended strand (participates in β ladder)trans-106.4138.9168.7-70.9163.2000109.3S7 T8 L12 W79S7-L77 CarbonylContact C-O 3.57Å; S7-L77 WeakPolarHBondContact CA-O 3.36Å; S7-L77 VanDerWaalsContact CB-O 3.25Å; S7-L77 WeakPolarHBondContact CB-O 3.23Å; T8-L77 PolarHBondContact N-O 2.82Å; T8-L77 PolarHBondContact O-N 3.19Å; L12-L77 HydrophobicContact CD1-CD1 3.66Å; L12-L77 HydrophobicContact CD2-CD1 3.35Å; L12-L77 HydrophobicContact CG-CD1 3.42Å; L12-L77 VanDerWaalsContact CG-CD1 3.42Å; L77-W79 HydrophobicContact CB-CH2 3.62Å; L77-W79 HydrophobicContact CB-CZ2 4.35Å; L77-W79 HydrophobicContact CB-CZ3 3.86Å; L77-W79 HydrophobicContact CD1-CH2 4.45Å
78V98.8Very high92.1Very high32 Ų3277.6 Ų77.619%0.19443%0.431CS..EExtended strand (participates in β ladder)trans-129.6133.5-176.8-172.70000109.8V6 M70 T71 V73 T76V6-V78 CarbonylContact O-C 3.57Å; V6-V78 VanDerWaalsContact O-CA 3.31Å; V6-V78 WeakPolarHBondContact O-CA 3.17Å; M70-V78 CarbonylContact C-O 3.6Å; M70-V78 VanDerWaalsContact CA-O 3.29Å; M70-V78 WeakPolarHBondContact CA-O 3.44Å; T71-V78 HydrophobicContact CG2-CB 4.35Å; T71-V78 PolarHBondContact N-O 3.18Å; T71-V78 PolarHBondContact O-N 2.99Å; V73-V78 HydrophobicContact CG1-CG2 4.26Å; T76-V78 HydrophobicContact CG2-CG2 4.16Å
79W98.8Very high89.7Confident22 Ų2283.3 Ų83.38%0.08347%0.466CS..EExtended strand (participates in β ladder)trans-112.1128.1170.2-64.8-97.9000109.5L5 V6 T8 L12 P53 L57 M70 L77L5-W79 WeakPolarHBondContact CA-O 3.25Å; V6-W79 PolarHBondContact N-O 2.91Å; V6-W79 PolarHBondContact O-N 3.13Å; T8-W79 HydrophobicContact CG2-CH2 4.25Å; T8-W79 HydrophobicContact CG2-CZ3 4.15Å; L12-W79 HydrophobicContact CD2-CH2 3.43Å; L12-W79 VanDerWaalsContact CD2-CH2 3.43Å; L12-W79 HydrophobicContact CD2-CZ2 3.85Å; P53-W79 HydrophobicContact CB-CE3 4.44Å; P53-W79 HydrophobicContact CB-CH2 3.83Å; P53-W79 HydrophobicContact CB-CZ3 3.79Å; P53-W79 HydrophobicContact CG-CH2 4.04Å; P53-W79 HydrophobicContact CG-CZ3 4.4Å; L57-W79 HydrophobicContact CD1-CD2 4.2Å; L57-W79 HydrophobicContact CD1-CG 4.08Å; L57-W79 HydrophobicContact CD2-CB 4.04Å; L57-W79 HydrophobicContact CD2-CG 4.06Å; M70-W79 HydrophobicContact CB-CG 4.49Å; M70-W79 HydrophobicContact CG-CD2 4.3Å; M70-W79 HydrophobicContact CG-CG 4.26Å; M70-W79 HydrophobicContact CG-CZ2 4.35Å; M70-W79 HydrophobicContact SD-CZ2 3.99Å; M70-W79 PolarHBondContact SD-NE1 3.05Å; M70-W79 VanDerWaalsContact SD-NE1 3.44Å; L77-W79 HydrophobicContact CB-CH2 3.62Å; L77-W79 HydrophobicContact CB-CZ2 4.35Å; L77-W79 HydrophobicContact CB-CZ3 3.86Å; L77-W79 HydrophobicContact CD1-CH2 4.45Å
80C98.7Very high89.3Confident27 Ų2783.4 Ų83.418%0.18246%0.464CS..EExtended strand (participates in β ladder)trans-91120.5166.7179.50000108.4L5 V68 T69L5-C80 HydrophobicContact CD2-CB 3.92Å; V68-C80 PolarHBondContact N-O 2.93Å; T69-C80 HydrophobicContact CG2-CB 3.78Å; T69-C80 PolarHBondContact O-N 3.03Å
81M98.5Very high88.8Confident3 Ų382.2 Ų82.22%0.01546%0.461CS..EExtended strand (participates in β ladder)trans-114.2143.9178-59.7-153.477.400111Y3 V4 L57 L60 F65 R66 V67Y3-M81 VanDerWaalsContact CA-O 3.3Å; Y3-M81 WeakPolarHBondContact CA-O 3.31Å; V4-M81 PolarHBondContact N-O 3.49Å; V4-M81 PolarHBondContact O-N 3.29Å; L57-M81 HydrophobicContact CD2-CE 4.17Å; L57-M81 HydrophobicContact CD2-CG 4.14Å; L57-M81 HydrophobicContact CD2-SD 3.31Å; L57-M81 WeakPolarHBondContact CD2-SD 3.45Å; L60-M81 HydrophobicContact CB-CE 4.23Å; L60-M81 HydrophobicContact CB-SD 3.79Å; L60-M81 HydrophobicContact CD1-SD 3.48Å; L60-M81 WeakPolarHBondContact CD1-SD 3.34Å; L60-M81 HydrophobicContact CG-SD 4.29Å; F65-M81 HydrophobicContact CB-CB 4.19Å; F65-M81 HydrophobicContact CB-CE 3.93Å; F65-M81 HydrophobicContact CB-SD 4.43Å; F65-M81 HydrophobicContact CD1-CB 4.15Å; R66-M81 CarbonylContact O-C 3.55Å; R66-M81 VanDerWaalsContact O-CA 3.27Å; R66-M81 WeakPolarHBondContact O-CA 3.25Å; V67-M81 HydrophobicContact CG2-CE 3.8Å
82Y98.2Very high88.3Confident29 Ų2981.9 Ų81.911%0.11446%0.457CS..EExtended strand (participates in β ladder)trans-129.7137.1179.1173.8-99.8000111.4P2 Y3 F65 R66 V68 E84P2-Y82 HydrophobicContact CB-CD2 4.24Å; P2-Y82 HydrophobicContact CB-CE2 3.9Å; P2-Y82 CarbonylContact O-C 3.55Å; P2-Y82 VanDerWaalsContact O-CA 3.29Å; P2-Y82 WeakPolarHBondContact O-CA 3.47Å; P2-Y82 WeakPolarHBondContact O-CD2 3.44Å; Y3-Y82 AromaticContact CD1-CD2 3.9Å; Y3-Y82 HydrophobicContact CD1-CD2 3.9Å; Y3-Y82 HydrophobicContact CD1-CG 4.4Å; Y3-Y82 AromaticContact CD2-CD2 3.96Å; Y3-Y82 HydrophobicContact CD2-CD2 3.96Å; Y3-Y82 HydrophobicContact CD2-CE2 4.44Å; Y3-Y82 AromaticContact CE1-CD2 3.5Å; Y3-Y82 HydrophobicContact CE1-CD2 3.5Å; Y3-Y82 VanDerWaalsContact CE1-CD2 3.5Å; Y3-Y82 HydrophobicContact CE1-CE2 4.48Å; Y3-Y82 AromaticContact CE1-CG 3.95Å; Y3-Y82 HydrophobicContact CE1-CG 3.95Å; Y3-Y82 AromaticContact CE2-CD2 3.53Å; Y3-Y82 HydrophobicContact CE2-CD2 3.53Å; Y3-Y82 AromaticContact CE2-CE2 3.82Å; Y3-Y82 HydrophobicContact CE2-CE2 3.82Å; Y3-Y82 HydrophobicContact CG-CD2 4.12Å; Y3-Y82 AromaticContact CZ-CD2 3.28Å; Y3-Y82 AromaticContact CZ-CE2 3.84Å; F65-Y82 CarbonylContact C-O 3.51Å; F65-Y82 WeakPolarHBondContact CA-O 3.38Å; R66-Y82 WeakPolarHBondContact CG-O 3.3Å; R66-Y82 VanDerWaalsContact CZ-CD1 3.47Å; R66-Y82 PolarHBondContact N-O 3.18Å; R66-Y82 VanDerWaalsContact NH2-CE1 3.28Å; R66-Y82 PolarHBondContact O-N 2.91Å; V68-Y82 VanDerWaalsContact CG2-CB 3.45Å; Y82-E84 HydrophobicContact CE1-CB 3.96Å
83K96.2Very high87.7Confident81 Ų8183.8 Ų83.835%0.35245%0.454SS..EExtended strand (participates in β ladder)trans-116.6128.5167.5173.5172.9179.7171.10108.5P2 I63 F65 T85P2-K83 PolarHBondContact O-N 2.85Å; I63-K83 WeakPolarHBondContact O-CD 3.29Å; I63-K83 VanDerWaalsContact O-CE 3.23Å; I63-K83 WeakPolarHBondContact O-CE 3.45Å; I63-K83 PolarHBondContact O-NZ 2.94Å; F65-K83 HydrophobicContact CD1-CB 3.52Å; F65-K83 HydrophobicContact CD2-CB 4.09Å; F65-K83 HydrophobicContact CD2-CD 4.31Å; F65-K83 HydrophobicContact CE1-CB 3.51Å; F65-K83 HydrophobicContact CE2-CB 4.09Å; F65-K83 HydrophobicContact CE2-CD 4Å; F65-K83 HydrophobicContact CG-CB 3.8Å; F65-K83 HydrophobicContact CZ-CB 3.8Å; F65-K83 HydrophobicContact CZ-CD 4.23Å; K83-T85 PolarHBondContact O-N 2.93Å
84E93.1Very high87.1Confident138 Ų13883.3 Ų83.365%0.64545%0.448SS*.  trans-63.8129.9173.5-167.2156.8-153.700109.5Y82Y82-E84 HydrophobicContact CE1-CB 3.96Å
85T83.9Confident86.4Confident43 Ų4383.9 Ų83.926%0.26443%0.426SS..  trans-104.5126.517344.90000107.3P2 K83 Y87P2-T85 HydrophobicContact CB-CG2 4.02Å; K83-T85 PolarHBondContact O-N 2.93Å; T85-Y87 VanDerWaalsContact C-N 3.28Å; T85-Y87 WeakPolarHBondContact O-CD2 3.39Å; T85-Y87 PolarHBondContact O-N 3.12Å; T85-Y87 WeakPolarHBondContact OG1-CE2 3.47Å; T85-Y87 PolarHBondContact OG1-OH 2.99Å
86D70Confident85.6Confident161 Ų16181.1 Ų81.186%0.86142%0.416SS*.  trans-6394.2170.8-61.9-39.7000108.1I88D86-I88 PolarHBondContact O-N 2.91Å
87Y59.7Low84.6Confident167 Ų16784.9 Ų84.966%0.65543%0.432SS*.  trans-73.8117.7167.1-64.2-77.4000106.5T85 T89T85-Y87 VanDerWaalsContact C-N 3.28Å; T85-Y87 WeakPolarHBondContact O-CD2 3.39Å; T85-Y87 PolarHBondContact O-N 3.12Å; T85-Y87 WeakPolarHBondContact OG1-CE2 3.47Å; T85-Y87 PolarHBondContact OG1-OH 2.99Å; Y87-T89 VanDerWaalsContact C-N 3.35Å; Y87-T89 PolarHBondContact O-N 3.21Å
88I56.6Low83.4Confident171 Ų17189.1 Ų89.188%0.87745%0.453SS*.  trans-68.3102.6160.1-57.6174.6000105.3D86D86-I88 PolarHBondContact O-N 2.91Å
89T48.6Very low82Confident195 Ų19594.3 Ų94.3100%1.19648%0.477SS*.  trans-67.90165440000111.1Y87Y87-T89 VanDerWaalsContact C-N 3.35Å; Y87-T89 PolarHBondContact O-N 3.21Å

Retrieved 89 of 89 residues in 101.1 ms (Link to these results)

U.S. Privacy Notice - Disclaimer / Registrations / Copyright Statement - Linking Policy - Notice of Privacy Practices (HIPAA) - Notice of Non‑Discrimination
© Copyright 2026 St. Jude Children's Research Hospital, a not-for-profit, section 501(c)(3).