A0A060WVH6_ONCMY Loading...

Serine peptidase inhibitor, Kunitz type 1 a

AlphaFold DB , UniProt , Accession A0A060WVH6, Species ONCMY (Oncorhynchus mykiss, Rainbow trout), Gene LOC100136686, Length 506 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M38.2Very low42.2Very low238 Ų238123.9 Ų123.9100%1.17272%0.717SS**  096.30-71.2166.371.400107.7
2T35.7Very low42.7Very low132 Ų132118.8 Ų118.881%0.8170%0.701SS**  trans-149.983.4-174.542.90000109.3
3T38.5Very low43.1Very low144 Ų144118.4 Ų118.488%0.88369%0.693SS**  trans-102.595.5170.446.50000108.5
4L37.2Very low43.7Very low144 Ų144115.9 Ų115.975%0.75468%0.679SS**  trans-66.8147168.9-108.670.2000110.1I6L4-I6 PolarHBondContact O-N 3.28Å
5P47.4Very low43.8Very low93 Ų93113.5 Ų113.560%0.60467%0.67SS**  trans-7992.6-176.131.9-34.4000111.6G7 L8P5-G7 PolarHBondContact O-N 3.28Å; P5-G7 VanDerWaalsContact O-N 3.1Å; P5-L8 PolarHBondContact O-N 3.09Å
6I46.9Very low43.7Very low131 Ų131115.5 Ų115.567%0.67267%0.668SS**Hα-helixtrans-58.7-20.9174.5-67.2167.7000112.2L4 L8 L10L4-I6 PolarHBondContact O-N 3.28Å; I6-L8 PolarHBondContact O-N 2.77Å; I6-L10 HydrophobicContact CG2-CD1 3.93Å
7G42.8Very low43.8Very low56 Ų56114.2 Ų114.258%0.57766%0.657SS**Hα-helixtrans-64.8-30.5-179.900000116P5 G11P5-G7 PolarHBondContact O-N 3.28Å; P5-G7 VanDerWaalsContact O-N 3.1Å; G7-G11 PolarHBondContact O-N 3.45Å; G7-G11 VanDerWaalsContact O-N 3.15Å
8L44.4Very low43.9Very low137 Ų137112.7 Ų112.772%0.71765%0.649SS**Hα-helixtrans-73.2-37.1-177.3-105.386.9000113P5 I6 A12P5-L8 PolarHBondContact O-N 3.09Å; I6-L8 PolarHBondContact O-N 2.77Å; L8-A12 WeakPolarHBondContact O-CB 3.49Å; L8-A12 PolarHBondContact O-N 2.82Å
9L42.5Very low43.6Very low143 Ų143115.6 Ų115.675%0.74965%0.654SS**Hα-helixtrans-71.1-37.4178.9-92.8120000112.3L13L9-L13 WeakPolarHBondContact O-CB 3.28Å; L9-L13 PolarHBondContact O-N 3.24Å
10L45.9Very low43.2Very low107 Ų107115.7 Ų115.756%0.5665%0.652SS**Hα-helixtrans-67.7-40.8174.6-88.9147.8000112.1I6 L13 V14I6-L10 HydrophobicContact CG2-CD1 3.93Å; L10-L13 PolarHBondContact O-N 3.17Å; L10-V14 WeakPolarHBondContact O-CB 3.21Å; L10-V14 WeakPolarHBondContact O-CG2 3.27Å; L10-V14 PolarHBondContact O-N 2.87Å
11G44.2Very low43Very low38 Ų38115.3 Ų115.339%0.39265%0.652SS.*Hα-helixtrans-61.6-45.2173.800000112.6G7 V14 C15G7-G11 PolarHBondContact O-N 3.45Å; G7-G11 VanDerWaalsContact O-N 3.15Å; G11-V14 PolarHBondContact O-N 3.46Å; G11-C15 WeakPolarHBondContact O-CB 3.19Å; G11-C15 PolarHBondContact O-N 3.34Å; G11-C15 PolarHBondContact O-SG 3.06Å; G11-C15 VanDerWaalsContact O-SG 3.42Å
12A48.8Very low42.9Very low63 Ų63113.9 Ų113.952%0.52163%0.634SS.*Hα-helixtrans-63.7-43.2176.700000112.5L8 C15 F16L8-A12 WeakPolarHBondContact O-CB 3.49Å; L8-A12 PolarHBondContact O-N 2.82Å; A12-C15 PolarHBondContact O-N 2.91Å; A12-F16 WeakPolarHBondContact O-CB 3.44Å; A12-F16 PolarHBondContact O-N 3.45Å
13L47.6Very low43Very low113 Ų113111.7 Ų111.759%0.59263%0.629SS**Hα-helixtrans-66-40.2179.4-155.385.8000112L9 L10 F16 I17L9-L13 WeakPolarHBondContact O-CB 3.28Å; L9-L13 PolarHBondContact O-N 3.24Å; L10-L13 PolarHBondContact O-N 3.17Å; L13-F16 PolarHBondContact O-N 3.5Å; L13-I17 HydrophobicContact CD2-CD1 4.34Å; L13-I17 HydrophobicContact CG-CD1 4.29Å; L13-I17 VanDerWaalsContact O-CG1 3.29Å; L13-I17 WeakPolarHBondContact O-CG1 3.4Å; L13-I17 PolarHBondContact O-N 3.46Å
14V51.5Low43.1Very low84 Ų84112.5 Ų112.551%0.50962%0.623SS.*Hα-helixtrans-67.8-41175.9172.80000111L10 G11 F16 I17 V18L10-V14 WeakPolarHBondContact O-CB 3.21Å; L10-V14 WeakPolarHBondContact O-CG2 3.27Å; L10-V14 PolarHBondContact O-N 2.87Å; G11-V14 PolarHBondContact O-N 3.46Å; V14-F16 VanDerWaalsContact C-N 3.34Å; V14-F16 PolarHBondContact O-N 3.12Å; V14-I17 PolarHBondContact O-N 3.4Å; V14-V18 HydrophobicContact CG1-CG2 4.43Å; V14-V18 WeakPolarHBondContact O-CB 3.46Å; V14-V18 VanDerWaalsContact O-CG2 3.3Å; V14-V18 WeakPolarHBondContact O-CG2 3.42Å; V14-V18 PolarHBondContact O-N 2.02Å
15C44.8Very low43.4Very low79 Ų79110.1 Ų110.153%0.53462%0.624SS.*Hα-helixtrans-61.9-40.2171.9-73.90000112.2G11 A12 V18 F19G11-C15 WeakPolarHBondContact O-CB 3.19Å; G11-C15 PolarHBondContact O-N 3.34Å; G11-C15 PolarHBondContact O-SG 3.06Å; G11-C15 VanDerWaalsContact O-SG 3.42Å; A12-C15 PolarHBondContact O-N 2.91Å; C15-V18 PolarHBondContact O-N 3.41Å; C15-F19 WeakPolarHBondContact O-CD2 3.39Å; C15-F19 PolarHBondContact O-N 2.82Å
16F42.9Very low43.3Very low146 Ų146110 Ų11064%0.6462%0.615SS**Hα-helixtrans-67.8-37.1178.1-140.4-94.5000112.2A12 L13 V14 F19 L20A12-F16 WeakPolarHBondContact O-CB 3.44Å; A12-F16 PolarHBondContact O-N 3.45Å; L13-F16 PolarHBondContact O-N 3.5Å; V14-F16 VanDerWaalsContact C-N 3.34Å; V14-F16 PolarHBondContact O-N 3.12Å; F16-F19 PolarHBondContact O-N 2.94Å; F16-L20 HydrophobicContact CD1-CD1 3.68Å; F16-L20 HydrophobicContact CD1-CG 4.12Å; F16-L20 HydrophobicContact CE1-CD1 4Å; F16-L20 HydrophobicContact CE1-CG 4.33Å; F16-L20 WeakPolarHBondContact O-CB 3.24Å; F16-L20 VanDerWaalsContact O-CG 3.3Å; F16-L20 WeakPolarHBondContact O-CG 3.03Å; F16-L20 PolarHBondContact O-N 2.86Å
17I45.6Very low43.7Very low93 Ų93107.8 Ų107.848%0.47761%0.609SS.*Hα-helixtrans-68.1-41173.2-69.1165.4000110.8L13 V14 F19 L20 V21L13-I17 HydrophobicContact CD2-CD1 4.34Å; L13-I17 HydrophobicContact CG-CD1 4.29Å; L13-I17 VanDerWaalsContact O-CG1 3.29Å; L13-I17 WeakPolarHBondContact O-CG1 3.4Å; L13-I17 PolarHBondContact O-N 3.46Å; V14-I17 PolarHBondContact O-N 3.4Å; I17-F19 VanDerWaalsContact C-N 3.33Å; I17-F19 PolarHBondContact O-N 3.14Å; I17-L20 PolarHBondContact O-N 2.92Å; I17-V21 HydrophobicContact CG2-CG2 4.28Å; I17-V21 WeakPolarHBondContact O-CB 3.19Å; I17-V21 VanDerWaalsContact O-CG2 3.23Å; I17-V21 WeakPolarHBondContact O-CG2 3.37Å; I17-V21 PolarHBondContact O-N 3.37Å
18V45.4Very low44.4Very low87 Ų87112.2 Ų112.253%0.52761%0.613SS.*Hα-helixtrans-66.1-33.4175.4170.60000112.1V14 C15 R22V14-V18 HydrophobicContact CG1-CG2 4.43Å; V14-V18 WeakPolarHBondContact O-CB 3.46Å; V14-V18 VanDerWaalsContact O-CG2 3.3Å; V14-V18 WeakPolarHBondContact O-CG2 3.42Å; V14-V18 PolarHBondContact O-N 2.02Å; C15-V18 PolarHBondContact O-N 3.41Å; V18-R22 PolarHBondContact O-N 2.98Å
19F38Very low45.1Very low169 Ų169106.8 Ų106.874%0.74159%0.59SS**Hα-helixtrans-73.5-38.9172.3-96.1-87000112.9C15 F16 I17 R22C15-F19 WeakPolarHBondContact O-CD2 3.39Å; C15-F19 PolarHBondContact O-N 2.82Å; F16-F19 PolarHBondContact O-N 2.94Å; I17-F19 VanDerWaalsContact C-N 3.33Å; I17-F19 PolarHBondContact O-N 3.14Å; F19-R22 PolarHBondContact O-N 3.3Å
20L36.1Very low46.2Very low117 Ų117104.1 Ų104.161%0.61357%0.574SS**Hα-helixtrans-71.3-29.1176.8-74.9172.2000113.3F16 I17 R22F16-L20 HydrophobicContact CD1-CD1 3.68Å; F16-L20 HydrophobicContact CD1-CG 4.12Å; F16-L20 HydrophobicContact CE1-CD1 4Å; F16-L20 HydrophobicContact CE1-CG 4.33Å; F16-L20 WeakPolarHBondContact O-CB 3.24Å; F16-L20 VanDerWaalsContact O-CG 3.3Å; F16-L20 WeakPolarHBondContact O-CG 3.03Å; F16-L20 PolarHBondContact O-N 2.86Å; I17-L20 PolarHBondContact O-N 2.92Å; L20-R22 PolarHBondContact O-N 3.46Å
21V38.4Very low47.7Very low108 Ų108104 Ų10466%0.65557%0.571SS**THydrogen-bonded Turntrans-77.1-11.5173.9171.80000112.1I17I17-V21 HydrophobicContact CG2-CG2 4.28Å; I17-V21 WeakPolarHBondContact O-CB 3.19Å; I17-V21 VanDerWaalsContact O-CG2 3.23Å; I17-V21 WeakPolarHBondContact O-CG2 3.37Å; I17-V21 PolarHBondContact O-N 3.37Å
22R36.3Very low49.6Very low207 Ų207102.7 Ų102.778%0.78156%0.555SS**THydrogen-bonded Turntrans-97.95.7178.4-123.3179-174.3-176.40.4115.4V18 F19 L20 E24V18-R22 PolarHBondContact O-N 2.98Å; F19-R22 PolarHBondContact O-N 3.3Å; L20-R22 PolarHBondContact O-N 3.46Å; R22-E24 PolarHBondContact O-N 3.49Å; R22-E24 VanDerWaalsContact O-N 3.11Å
23A36.9Very low51.3Low86 Ų86101.1 Ų101.171%0.71154%0.538SS*.  trans-80.854.3158.700000109.8A25A23-A25 PolarHBondContact O-N 2.94Å
24E41Very low53Low162 Ų162101.5 Ų101.576%0.75754%0.541SS*.  trans-62.1118.4161.4-73.7177.5135.400106.1R22 Q26R22-E24 PolarHBondContact O-N 3.49Å; R22-E24 VanDerWaalsContact O-N 3.11Å; E24-Q26 PolarHBondContact O-N 2.91Å
25A43.8Very low54.6Low94 Ų9499 Ų9978%0.77753%0.527SS*.  trans-58.7110.5167.700000106.4A23A23-A25 PolarHBondContact O-N 2.94Å
26Q44.9Very low56.6Low89 Ų8995.9 Ų95.942%0.41650%0.504SS..  trans-48.9133.2177.1-75.5168.7-69.100108.1E24 F28 Q31E24-Q26 PolarHBondContact O-N 2.91Å; Q26-F28 PolarHBondContact O-N 3.39Å; Q26-Q31 HydrophobicContact CB-CG 3.82Å
27P55.5Low58.6Low85 Ų8592.1 Ų92.155%0.55249%0.489SS*.  trans-55.3137.2177.821.5-29.9000108.4G29 E30P27-G29 PolarHBondContact O-N 3.49Å; P27-E30 HydrophobicContact CG-CG 4.17Å; P27-E30 PolarHBondContact O-N 2.88Å
28F57.1Low60.6Low149 Ų14992.2 Ų92.265%0.65449%0.485SS*.Hα-helixtrans-46.4-32.1-173.2173.6-96.3000114.3Q26 E30 C32 C74Q26-F28 PolarHBondContact O-N 3.39Å; F28-E30 VanDerWaalsContact C-N 3.32Å; F28-E30 PolarHBondContact O-N 2.87Å; F28-C32 WeakPolarHBondContact O-CB 3.3Å; F28-C32 PolarHBondContact O-N 2.9Å; F28-C32 VanDerWaalsContact O-N 3.13Å; F28-C74 WeakPolarHBondContact CE1-O 3.45Å
29G59.6Low62.2Low23 Ų2388.3 Ų88.324%0.23746%0.463CS..Hα-helixtrans-73.9-5.1175.900000116.8P27 L33P27-G29 PolarHBondContact O-N 3.49Å; G29-L33 VanDerWaalsContact O-CD1 3.31Å; G29-L33 WeakPolarHBondContact O-CD1 3.26Å; G29-L33 VanDerWaalsContact O-CG 3.3Å; G29-L33 WeakPolarHBondContact O-CG 3.48Å
30E66.9Low64.2Low87 Ų8784.2 Ų84.241%0.40744%0.443SS..Hα-helixtrans-94.2-48.8168-72.6-169164.800111.1P27 F28 C32 L33 D34P27-E30 HydrophobicContact CG-CG 4.17Å; P27-E30 PolarHBondContact O-N 2.88Å; F28-E30 VanDerWaalsContact C-N 3.32Å; F28-E30 PolarHBondContact O-N 2.87Å; E30-C32 PolarHBondContact O-N 3.41Å; E30-C32 VanDerWaalsContact O-N 3.16Å; E30-L33 WeakPolarHBondContact O-CB 3.37Å; E30-L33 PolarHBondContact O-N 3.34Å; E30-D34 PolarHBondContact O-N 2.91Å
31Q77.4Confident66.6Low106 Ų10683.6 Ų83.650%0.49544%0.437SS..Hα-helixtrans-58.8-31.4175.2-67.4-176.6-2100112.9Q26Q26-Q31 HydrophobicContact CB-CG 3.82Å
32C82.6Confident69Low10 Ų1080.8 Ų80.87%0.06842%0.418CS..THydrogen-bonded Turntrans-75.4-27.9174.5-177.30000113.3F28 E30 D34 S35 F36 C74F28-C32 WeakPolarHBondContact O-CB 3.3Å; F28-C32 PolarHBondContact O-N 2.9Å; F28-C32 VanDerWaalsContact O-N 3.13Å; E30-C32 PolarHBondContact O-N 3.41Å; E30-C32 VanDerWaalsContact O-N 3.16Å; C32-D34 VanDerWaalsContact C-N 3.27Å; C32-D34 PolarHBondContact O-N 3.42Å; C32-S35 PolarHBondContact O-N 3.5Å; C32-S35 VanDerWaalsContact O-N 3.14Å; C32-S35 PolarHBondContact O-OG 3.49Å; C32-F36 WeakPolarHBondContact O-CD2 3.35Å; C32-C74 HydrophobicContact CB-CB 3.75Å; C32-C74 WeakPolarHBondContact CB-SG 3.13Å; C32-C74 VanDerWaalsContact SG-CA 3.58Å; C32-C74 WeakPolarHBondContact SG-CB 3.25Å; C32-C74 CovalentContact SG-SG 2.03Å; C32-C74 PolarHBondContact SG-SG 2.77Å
33L84.3Confident71.5Confident29 Ų2971 Ų7115%0.15238%0.381CS..G310 helixtrans-63.3-37.4174.8-78.2165.3000111.3G29 E30 S35 F36 N67 I70 R71G29-L33 VanDerWaalsContact O-CD1 3.31Å; G29-L33 WeakPolarHBondContact O-CD1 3.26Å; G29-L33 VanDerWaalsContact O-CG 3.3Å; G29-L33 WeakPolarHBondContact O-CG 3.48Å; E30-L33 WeakPolarHBondContact O-CB 3.37Å; E30-L33 PolarHBondContact O-N 3.34Å; L33-S35 PolarHBondContact O-N 3.31Å; L33-F36 PolarHBondContact O-N 2.93Å; L33-N67 HydrophobicContact CD1-CB 4.5Å; L33-N67 HydrophobicContact CD2-CB 4.29Å; L33-I70 HydrophobicContact CD2-CB 3.64Å; L33-I70 HydrophobicContact CD2-CD1 4Å; L33-I70 HydrophobicContact CD2-CG1 4.45Å; L33-I70 HydrophobicContact CD2-CG2 3.69Å; L33-R71 HydrophobicContact CD1-CG 4.38Å; L33-R71 HydrophobicContact CG-CG 4.42Å
34D84.3Confident74Confident122 Ų12267 Ų6765%0.65235%0.348SS*.G310 helixtrans-67-13.9177.4-60.5-26.8000113E30 C32E30-D34 PolarHBondContact O-N 2.91Å; C32-D34 VanDerWaalsContact C-N 3.27Å; C32-D34 PolarHBondContact O-N 3.42Å
35S85.7Confident76.4Confident31 Ų3159.4 Ų59.422%0.21731%0.312CS..G310 helixtrans-95.115.9178.273.50000114.8C32 L33 R122 D123C32-S35 PolarHBondContact O-N 3.5Å; C32-S35 VanDerWaalsContact O-N 3.14Å; C32-S35 PolarHBondContact O-OG 3.49Å; L33-S35 PolarHBondContact O-N 3.31Å; S35-R122 VanDerWaalsContact O-CA 3.3Å; S35-R122 WeakPolarHBondContact O-CA 3.38Å; S35-R122 VanDerWaalsContact O-CG 3.25Å; S35-R122 WeakPolarHBondContact O-CG 3.46Å; S35-R122 PolarHBondContact OG-NH1 2.53Å; S35-D123 VanDerWaalsContact CA-OD2 3.3Å; S35-D123 WeakPolarHBondContact CA-OD2 3.23Å; S35-D123 PolarHBondContact O-N 3.36Å; S35-D123 VanDerWaalsContact O-N 3.17Å; S35-D123 VanDerWaalsContact O-OD1 3.1Å
36F86.9Confident78.7Confident14 Ų1455.7 Ų55.76%0.06128%0.279CS..EExtended strand (participates in β ladder)trans-128.9107.6177.9-81.9-94.9000111.4C32 L33 I70 C73 Y120 I121 R122 D123C32-F36 WeakPolarHBondContact O-CD2 3.35Å; L33-F36 PolarHBondContact O-N 2.93Å; F36-I70 HydrophobicContact CB-CG2 4.09Å; F36-I70 HydrophobicContact CD1-CG2 4.32Å; F36-I70 HydrophobicContact CD2-CG2 3.57Å; F36-I70 HydrophobicContact CE2-CG2 4.03Å; F36-I70 HydrophobicContact CG-CG2 3.74Å; F36-C73 HydrophobicContact CZ-CB 4.13Å; F36-C73 WeakPolarHBondContact CZ-SG 3.48Å; F36-Y120 HydrophobicContact CB-CD1 4.41Å; F36-I121 CarbonylContact C-O 3.42Å; F36-I121 WeakPolarHBondContact CA-O 3.24Å; F36-R122 HydrophobicContact CD1-CB 4.2Å; F36-R122 HydrophobicContact CE1-CB 3.86Å; F36-R122 HydrophobicContact CE2-CB 4.43Å; F36-R122 HydrophobicContact CE2-CG 4.33Å; F36-R122 HydrophobicContact CZ-CB 3.97Å; F36-R122 HydrophobicContact CZ-CG 4.29Å; F36-D123 PolarHBondContact N-OD1 3.24Å
37E84.9Confident80.9Confident67 Ų6751.6 Ų51.631%0.31326%0.261SS..EExtended strand (participates in β ladder)trans-67.8138.2167.2-74.7-164-158.700112.6G39 Y120 I121 D123 Y126E37-G39 PolarHBondContact O-N 3.37Å; E37-Y120 WeakPolarHBondContact O-CA 3.49Å; E37-I121 PolarHBondContact N-O 3.38Å; E37-I121 PolarHBondContact O-N 2.7Å; E37-D123 PolarHBondContact N-OD1 3.33Å; E37-D123 VanDerWaalsContact N-OD1 3.15Å; E37-Y126 WeakPolarHBondContact OE2-CE2 3.34Å; E37-Y126 PolarHBondContact OE2-OH 3.48Å
38K85.9Confident82.7Confident94 Ų9451.4 Ų51.441%0.40926%0.255SS..EExtended strand (participates in β ladder)trans-77.3110.8169.3-177.1-176.6174.8-177.50108.9E41 Y120K38-E41 WeakPolarHBondContact CE-OE1 3.33Å; K38-E41 IonicContact NZ-OE1 2.91Å; K38-E41 PolarHBondContact NZ-OE1 3.24Å; K38-Y120 HydrophobicContact CB-CD1 4.1Å; K38-Y120 HydrophobicContact CB-CE1 3.6Å; K38-Y120 HydrophobicContact CG-CE1 4.02Å; K38-Y120 HydrophobicContact CG-CE2 4.13Å
39G79.1Confident84.2Confident6 Ų645 Ų456%0.06223%0.227CC..  trans-76.6-171.3177.400000113.7E37 E41 N119E37-G39 PolarHBondContact O-N 3.37Å; G39-E41 PolarHBondContact O-N 3.44Å; G39-N119 VanDerWaalsContact C-OD1 3.27Å; G39-N119 WeakPolarHBondContact CA-OD1 3.43Å; G39-N119 PolarHBondContact N-O 3.18Å
40R81Confident85.8Confident83 Ų8343.9 Ų43.931%0.31322%0.216SC..  trans-69128.1-171.9-164.8171.5-173.4-177.715.8111.5F43 N119 E425 I428 F429R40-F43 HydrophobicContact CB-CD2 3.99Å; R40-F43 HydrophobicContact CB-CE2 4.29Å; R40-F43 VanDerWaalsContact CD-CE2 3.43Å; R40-F43 HydrophobicContact CG-CD2 3.84Å; R40-F43 HydrophobicContact CG-CE2 3.75Å; R40-N119 PolarHBondContact N-OD1 3.03Å; R40-N119 PolarHBondContact O-ND2 2.94Å; R40-E425 PolarHBondContact NH1-O 2.93Å; R40-I428 PolarHBondContact NH1-O 2.82Å; R40-F429 HydrophobicContact CB-CD2 3.97Å; R40-F429 HydrophobicContact CB-CE2 3.88Å
41E85.3Confident87.1Confident103 Ų10339.7 Ų39.748%0.48120%0.197SC..SBendtrans-66.8155.7175.1-47.4-162.8149.400112.1K38 G39 F43 L118K38-E41 WeakPolarHBondContact CE-OE1 3.33Å; K38-E41 IonicContact NZ-OE1 2.91Å; K38-E41 PolarHBondContact NZ-OE1 3.24Å; G39-E41 PolarHBondContact O-N 3.44Å; E41-F43 VanDerWaalsContact C-N 3.34Å; E41-F43 WeakPolarHBondContact O-CD2 3.21Å; E41-L118 HydrophobicContact CB-CD2 3.86Å; E41-L118 HydrophobicContact CG-CD2 3.52Å
42D88.9Confident87.8Confident50 Ų5038 Ų3827%0.26719%0.188SC..SBendtrans62.137.4-173.7-70.4-18.7000113R113 K114 K115 G116 F117D42-R113 CarbonylContact O-C 3.56Å; D42-R113 VanDerWaalsContact O-CA 3.29Å; D42-R113 WeakPolarHBondContact O-CA 3.25Å; D42-R113 WeakPolarHBondContact O-CG 3.4Å; D42-K114 CarbonylContact C-O 3.58Å; D42-K114 VanDerWaalsContact CA-O 3.24Å; D42-K114 WeakPolarHBondContact CA-O 3.45Å; D42-K114 CarbonylContact O-C 3.5Å; D42-K114 PolarHBondContact O-N 3.07Å; D42-K114 VanDerWaalsContact O-O 3.12Å; D42-K115 HydrophobicContact CB-CG 4.43Å; D42-K115 WeakPolarHBondContact OD1-CA 3.29Å; D42-G116 PolarHBondContact OD1-N 3.39Å; D42-F117 PolarHBondContact N-O 2.7Å
43F88.9Confident88.2Confident2 Ų240.8 Ų40.81%0.00920%0.197CC..EExtended strand (participates in β ladder)trans-130.8135.5170.5-77.8-103.2000111.8R40 E41 F111 V112 R113 F117 N119 D427 I428 F429R40-F43 HydrophobicContact CB-CD2 3.99Å; R40-F43 HydrophobicContact CB-CE2 4.29Å; R40-F43 VanDerWaalsContact CD-CE2 3.43Å; R40-F43 HydrophobicContact CG-CD2 3.84Å; R40-F43 HydrophobicContact CG-CE2 3.75Å; E41-F43 VanDerWaalsContact C-N 3.34Å; E41-F43 WeakPolarHBondContact O-CD2 3.21Å; F43-F111 HydrophobicContact CB-CB 4.36Å; F43-F111 HydrophobicContact CD1-CB 4.16Å; F43-V112 WeakPolarHBondContact CA-O 3.41Å; F43-V112 VanDerWaalsContact CD1-C 3.47Å; F43-R113 HydrophobicContact CD1-CB 4.17Å; F43-R113 HydrophobicContact CD2-CG 4.44Å; F43-R113 HydrophobicContact CE1-CB 3.74Å; F43-R113 HydrophobicContact CE1-CG 4.39Å; F43-R113 HydrophobicContact CE2-CB 4.21Å; F43-R113 HydrophobicContact CE2-CG 3.96Å; F43-R113 HydrophobicContact CZ-CB 3.76Å; F43-R113 HydrophobicContact CZ-CG 3.94Å; F43-F117 VanDerWaalsContact O-CB 3.28Å; F43-F117 WeakPolarHBondContact O-CB 3.43Å; F43-N119 PolarHBondContact O-ND2 2.93Å; F43-N119 VanDerWaalsContact O-ND2 3.11Å; F43-D427 WeakPolarHBondContact CE1-O 3.43Å; F43-I428 VanDerWaalsContact CZ-O 3.29Å; F43-I428 WeakPolarHBondContact CZ-O 3.27Å; F43-F429 HydrophobicContact CB-CD2 3.7Å; F43-F429 HydrophobicContact CB-CE2 3.94Å; F43-F429 HydrophobicContact CD1-CB 3.84Å; F43-F429 AromaticContact CD1-CD2 3.61Å; F43-F429 HydrophobicContact CD1-CD2 3.61Å; F43-F429 HydrophobicContact CD1-CG 4.17Å; F43-F429 HydrophobicContact CD2-CD2 4.15Å; F43-F429 HydrophobicContact CE1-CB 3.85Å; F43-F429 HydrophobicContact CE1-CD2 4.25Å; F43-F429 AromaticContact CG-CD2 3.56Å; F43-F429 HydrophobicContact CG-CD2 3.56Å; F43-F429 HydrophobicContact CG-CE2 4.24Å
44V90.7Very high88.6Confident1 Ų139.6 Ų39.61%0.00619%0.192CC..EExtended strand (participates in β ladder)trans-115.5152.2176.373.50000110.1D46 F83 F111 V112 K114 F117 I361V44-D46 PolarHBondContact O-N 3.4Å; V44-F83 HydrophobicContact CG2-CD2 4.25Å; V44-F83 HydrophobicContact CG2-CE2 3.99Å; V44-F111 WeakPolarHBondContact O-CA 3.4Å; V44-V112 PolarHBondContact N-O 3.23Å; V44-V112 PolarHBondContact O-N 3.17Å; V44-K114 HydrophobicContact CB-CB 4.09Å; V44-K114 HydrophobicContact CB-CD 4.16Å; V44-K114 HydrophobicContact CG1-CB 3.63Å; V44-K114 HydrophobicContact CG1-CD 3.67Å; V44-K114 HydrophobicContact CG1-CG 4.3Å; V44-F117 HydrophobicContact CB-CB 4.2Å; V44-F117 HydrophobicContact CB-CD1 4.08Å; V44-F117 HydrophobicContact CB-CD2 4.17Å; V44-F117 HydrophobicContact CB-CG 3.87Å; V44-F117 HydrophobicContact CG2-CD1 3.59Å; V44-F117 HydrophobicContact CG2-CD2 4.37Å; V44-F117 HydrophobicContact CG2-CE1 3.76Å; V44-F117 HydrophobicContact CG2-CG 3.92Å; V44-F117 HydrophobicContact CG2-CZ 4.25Å; V44-I361 HydrophobicContact CG1-CG2 4.22Å; V44-I361 HydrophobicContact CG2-CD1 4.04Å; V44-I361 HydrophobicContact CG2-CG2 4.25Å
45L90.7Very high89Confident2 Ų233.8 Ų33.81%0.0116%0.161CC..EExtended strand (participates in β ladder)trans-70.2124.8171-170.476.8000110.2T47 S50 F83 F99 C109 R110 F111L45-T47 PolarHBondContact O-N 3.4Å; L45-T47 PolarHBondContact O-OG1 3.5Å; L45-S50 WeakPolarHBondContact CD1-OG 3.24Å; L45-F83 HydrophobicContact CB-CD1 3.69Å; L45-F83 HydrophobicContact CB-CE1 3.45Å; L45-F83 VanDerWaalsContact CB-CE1 3.45Å; L45-F83 HydrophobicContact CB-CG 4.34Å; L45-F83 HydrophobicContact CB-CZ 3.95Å; L45-F83 HydrophobicContact CD2-CD1 4.2Å; L45-F83 HydrophobicContact CD2-CE1 3.66Å; L45-F83 HydrophobicContact CG-CE1 4.19Å; L45-F99 HydrophobicContact CD2-CB 4.47Å; L45-F99 HydrophobicContact CD2-CD1 3.69Å; L45-F99 HydrophobicContact CD2-CD2 3.85Å; L45-F99 HydrophobicContact CD2-CE1 3.77Å; L45-F99 HydrophobicContact CD2-CE2 3.95Å; L45-F99 HydrophobicContact CD2-CG 3.73Å; L45-F99 HydrophobicContact CD2-CZ 3.9Å; L45-C109 HydrophobicContact CD1-CB 3.56Å; L45-R110 CarbonylContact C-O 3.1Å; L45-R110 WeakPolarHBondContact CA-O 3.26Å; L45-R110 WeakPolarHBondContact CD1-O 3.12Å; L45-F111 HydrophobicContact CB-CD1 4.39Å; L45-F111 HydrophobicContact CB-CE1 4.15Å; L45-F111 HydrophobicContact CD1-CD1 4.37Å; L45-F111 HydrophobicContact CD1-CE1 4.03Å; L45-F111 HydrophobicContact CD1-CE2 4.47Å; L45-F111 HydrophobicContact CD1-CZ 4.1Å
46D91.6Very high89.4Confident16 Ų1633.1 Ų33.19%0.08616%0.156CC..  trans-71.395.3164.7-171-25.5000108.2V44 D48 D49 S50 R110 V112V44-D46 PolarHBondContact O-N 3.4Å; D46-D48 VanDerWaalsContact C-N 3.35Å; D46-D48 PolarHBondContact OD1-N 2.85Å; D46-D49 PolarHBondContact OD1-N 3.37Å; D46-S50 WeakPolarHBondContact O-CB 3.36Å; D46-S50 PolarHBondContact O-N 2.89Å; D46-S50 PolarHBondContact O-OG 3.34Å; D46-R110 HydrophobicContact CB-CB 4.32Å; D46-R110 HydrophobicContact CB-CG 4.36Å; D46-R110 PolarHBondContact N-O 3.32Å; D46-V112 HydrophobicContact CB-CG2 3.97Å
47T92.6Very high89.8Confident4 Ų432.5 Ų32.53%0.02515%0.153CC..Hα-helixtrans-71.4-31.2-170.8-60.80000112.1L45 V51 F99 F355 L358 L359L45-T47 PolarHBondContact O-N 3.4Å; L45-T47 PolarHBondContact O-OG1 3.5Å; T47-V51 HydrophobicContact CG2-CG2 4.22Å; T47-V51 WeakPolarHBondContact O-CB 3.25Å; T47-V51 WeakPolarHBondContact O-CG2 3.4Å; T47-V51 PolarHBondContact O-N 2.85Å; T47-F99 HydrophobicContact CG2-CE1 4.15Å; T47-F99 HydrophobicContact CG2-CZ 3.83Å; T47-F355 HydrophobicContact CG2-CD2 4.29Å; T47-F355 HydrophobicContact CG2-CE2 3.6Å; T47-F355 HydrophobicContact CG2-CZ 4.13Å; T47-L358 HydrophobicContact CG2-CB 3.91Å; T47-L358 HydrophobicContact CG2-CD1 4.3Å; T47-L359 HydrophobicContact CG2-CD2 4.06Å
48D91.4Very high90.1Very high80 Ų8029.7 Ų29.743%0.42814%0.14SC..Hα-helixtrans-69.7-52.7179.6-167.177.5000110.1D46 S50 V51 K52 F252 L359D46-D48 VanDerWaalsContact C-N 3.35Å; D46-D48 PolarHBondContact OD1-N 2.85Å; D48-S50 PolarHBondContact O-N 2.87Å; D48-V51 PolarHBondContact O-N 3.26Å; D48-K52 VanDerWaalsContact O-CB 3.22Å; D48-K52 WeakPolarHBondContact O-CB 3.45Å; D48-K52 PolarHBondContact O-N 2.85Å; D48-F252 VanDerWaalsContact O-CE1 3.28Å; D48-F252 WeakPolarHBondContact O-CE1 3.31Å; D48-F252 WeakPolarHBondContact OD1-CE1 3.23Å; D48-L359 HydrophobicContact CB-CD2 4.12Å
49D90Very high90.4Very high14 Ų1429 Ų298%0.07514%0.14CC..Hα-helixtrans-69.5-37.7-177.9-161.365000112.3D46 V51 K52 Y53 R110D46-D49 PolarHBondContact OD1-N 3.37Å; D49-V51 PolarHBondContact O-N 2.88Å; D49-K52 WeakPolarHBondContact O-CB 3.26Å; D49-K52 PolarHBondContact O-N 3.34Å; D49-K52 IonicContact OD1-NZ 3.75Å; D49-K52 PolarHBondContact OD1-NZ 2.87Å; D49-Y53 WeakPolarHBondContact O-CD2 3.33Å; D49-Y53 PolarHBondContact O-N 3.38Å; D49-Y53 WeakPolarHBondContact OD1-CE2 3.47Å; D49-Y53 WeakPolarHBondContact OD2-CE2 3.31Å; D49-R110 WeakPolarHBondContact OD2-CD 3.4Å; D49-R110 IonicContact OD2-CZ 2.64Å; D49-R110 IonicContact OD2-NE 3.31Å; D49-R110 IonicContact OD2-NH1 3.4Å; D49-R110 PolarHBondContact OD2-NH1 2.84Å
50S92.3Very high91.1Very high0 Ų030.9 Ų30.90%015%0.146CC..Hα-helixtrans-61.7-44.4176.2-56.60000112.3L45 D46 D48 Y53 G54 A55 R110L45-S50 WeakPolarHBondContact CD1-OG 3.24Å; D46-S50 WeakPolarHBondContact O-CB 3.36Å; D46-S50 PolarHBondContact O-N 2.89Å; D46-S50 PolarHBondContact O-OG 3.34Å; D48-S50 PolarHBondContact O-N 2.87Å; S50-Y53 CarbonylContact O-C 3.58Å; S50-Y53 PolarHBondContact O-N 2.84Å; S50-G54 PolarHBondContact O-N 3.37Å; S50-G54 VanDerWaalsContact O-N 3.17Å; S50-A55 WeakPolarHBondContact O-CB 3.25Å; S50-A55 PolarHBondContact O-N 3.43Å; S50-R110 PolarHBondContact OG-N 3.26Å
51V94.5Very high91.7Very high0 Ų027.8 Ų27.80%014%0.137CC..Hα-helixtrans-74.9-32.4-178.4176.10000111.6T47 D48 D49 Y53 G54 A55 F99 F252 R254 F355T47-V51 HydrophobicContact CG2-CG2 4.22Å; T47-V51 WeakPolarHBondContact O-CB 3.25Å; T47-V51 WeakPolarHBondContact O-CG2 3.4Å; T47-V51 PolarHBondContact O-N 2.85Å; D48-V51 PolarHBondContact O-N 3.26Å; D49-V51 PolarHBondContact O-N 2.88Å; V51-Y53 VanDerWaalsContact C-N 3.29Å; V51-Y53 PolarHBondContact O-N 3.35Å; V51-G54 PolarHBondContact O-N 2.85Å; V51-G54 VanDerWaalsContact O-N 3.09Å; V51-A55 WeakPolarHBondContact CA-O 3.4Å; V51-F99 HydrophobicContact CG2-CE1 4.16Å; V51-F252 HydrophobicContact CB-CD1 4.36Å; V51-F252 HydrophobicContact CB-CD2 4.48Å; V51-F252 HydrophobicContact CB-CE1 4.01Å; V51-F252 HydrophobicContact CB-CE2 4.12Å; V51-F252 HydrophobicContact CB-CZ 3.87Å; V51-F252 HydrophobicContact CG1-CD1 4.13Å; V51-F252 HydrophobicContact CG1-CD2 3.55Å; V51-F252 HydrophobicContact CG1-CE1 4.09Å; V51-F252 HydrophobicContact CG1-CE2 3.49Å; V51-F252 VanDerWaalsContact CG1-CE2 3.49Å; V51-F252 HydrophobicContact CG1-CG 3.88Å; V51-F252 HydrophobicContact CG1-CZ 3.78Å; V51-R254 PolarHBondContact O-NH2 2.83Å; V51-F355 HydrophobicContact CG1-CZ 4.45Å; V51-F355 HydrophobicContact CG2-CE2 4.12Å; V51-F355 HydrophobicContact CG2-CZ 4.19Å
52K92.2Very high92Very high70 Ų7031.8 Ų31.830%0.30415%0.153SC..Hα-helixtrans-57.6-39168.3170-176.2161-153.30112D48 D49 F252 L280D48-K52 VanDerWaalsContact O-CB 3.22Å; D48-K52 WeakPolarHBondContact O-CB 3.45Å; D48-K52 PolarHBondContact O-N 2.85Å; D49-K52 WeakPolarHBondContact O-CB 3.26Å; D49-K52 PolarHBondContact O-N 3.34Å; D49-K52 IonicContact OD1-NZ 3.75Å; D49-K52 PolarHBondContact OD1-NZ 2.87Å; K52-F252 HydrophobicContact CB-CD1 4Å; K52-F252 HydrophobicContact CB-CE1 4.46Å; K52-L280 WeakPolarHBondContact O-CD2 3.28Å
53Y89.9Confident92.2Very high68 Ų6831 Ų3127%0.26715%0.15SC..THydrogen-bonded Turntrans-86.42.7173.9-71.3-65.5000115.2D49 S50 V51 V108 L280D49-Y53 WeakPolarHBondContact O-CD2 3.33Å; D49-Y53 PolarHBondContact O-N 3.38Å; D49-Y53 WeakPolarHBondContact OD1-CE2 3.47Å; D49-Y53 WeakPolarHBondContact OD2-CE2 3.31Å; S50-Y53 CarbonylContact O-C 3.58Å; S50-Y53 PolarHBondContact O-N 2.84Å; V51-Y53 VanDerWaalsContact C-N 3.29Å; V51-Y53 PolarHBondContact O-N 3.35Å; Y53-V108 WeakPolarHBondContact O-CB 3.32Å; Y53-V108 VanDerWaalsContact O-CG1 3.31Å; Y53-V108 WeakPolarHBondContact O-CG1 3.37Å; Y53-L280 VanDerWaalsContact O-CD1 3.23Å; Y53-L280 WeakPolarHBondContact O-CD1 3.46Å
54G92.7Very high92.4Very high4 Ų438.9 Ų38.94%0.04119%0.186CC..THydrogen-bonded Turntrans113.61.7168.700000116.2S50 V51S50-G54 PolarHBondContact O-N 3.37Å; S50-G54 VanDerWaalsContact O-N 3.17Å; V51-G54 PolarHBondContact O-N 2.85Å; V51-G54 VanDerWaalsContact O-N 3.09Å
55A94.6Very high92.5Very high0 Ų040.6 Ų40.60%020%0.199CC..  trans-61.6146.5170.800000110.9S50 V51 D100 V108S50-A55 WeakPolarHBondContact O-CB 3.25Å; S50-A55 PolarHBondContact O-N 3.43Å; V51-A55 WeakPolarHBondContact CA-O 3.4Å; A55-D100 CarbonylContact C-O 3.5Å; A55-D100 WeakPolarHBondContact CA-O 3.39Å; A55-D100 WeakPolarHBondContact CB-O 3.34Å; A55-V108 HydrophobicContact CB-CG2 4.16Å
56T92.9Very high92.5Very high18 Ų1841 Ų4111%0.1120%0.201CC..EExtended strand (participates in β ladder)trans-115.4125.3177.3-69.10000110.1I58 D100 E274T56-I58 PolarHBondContact O-N 2.94Å; T56-D100 PolarHBondContact N-O 3.38Å; T56-D100 PolarHBondContact O-N 3.48Å; T56-E274 WeakPolarHBondContact CG2-OE2 3.03Å; T56-E274 PolarHBondContact OG1-OE1 2.93Å; T56-E274 PolarHBondContact OG1-OE2 3.29Å
57F94.6Very high92.5Very high1 Ų143.8 Ų43.80%0.00422%0.216CC..EExtended strand (participates in β ladder)trans-71.1122.4167.8174.8-126.7000110I59 K60 F97 F99 C272 L351 N354 F355 L358F57-I59 WeakPolarHBondContact CE2-O 3.19Å; F57-K60 HydrophobicContact CZ-CB 4.28Å; F57-F97 HydrophobicContact CE2-CD1 4.24Å; F57-F99 HydrophobicContact CB-CD1 4.37Å; F57-F99 HydrophobicContact CB-CE1 3.74Å; F57-F99 HydrophobicContact CB-CZ 3.82Å; F57-F99 HydrophobicContact CD2-CD2 4.12Å; F57-F99 HydrophobicContact CD2-CE1 4.27Å; F57-F99 AromaticContact CD2-CE2 3.49Å; F57-F99 HydrophobicContact CD2-CE2 3.49Å; F57-F99 VanDerWaalsContact CD2-CE2 3.49Å; F57-F99 AromaticContact CD2-CZ 3.59Å; F57-F99 HydrophobicContact CD2-CZ 3.59Å; F57-F99 HydrophobicContact CE2-CE2 4.16Å; F57-F99 HydrophobicContact CG-CE1 4.46Å; F57-F99 HydrophobicContact CG-CE2 4.39Å; F57-F99 HydrophobicContact CG-CZ 4.05Å; F57-C272 HydrophobicContact CB-CB 4.47Å; F57-C272 HydrophobicContact CD1-CB 4.43Å; F57-L351 HydrophobicContact CD1-CD1 3.93Å; F57-L351 HydrophobicContact CD1-CG 4.44Å; F57-L351 HydrophobicContact CE1-CD1 3.52Å; F57-L351 HydrophobicContact CE1-CG 4.2Å; F57-L351 HydrophobicContact CZ-CD1 4.3Å; F57-N354 HydrophobicContact CE1-CB 4.33Å; F57-N354 HydrophobicContact CZ-CB 4.12Å; F57-F355 HydrophobicContact CB-CD2 3.68Å; F57-F355 HydrophobicContact CB-CE2 3.82Å; F57-F355 HydrophobicContact CD1-CB 3.86Å; F57-F355 AromaticContact CD1-CD2 3.55Å; F57-F355 HydrophobicContact CD1-CD2 3.55Å; F57-F355 HydrophobicContact CD1-CG 4.11Å; F57-F355 HydrophobicContact CE1-CB 3.94Å; F57-F355 HydrophobicContact CE1-CD2 4.34Å; F57-F355 AromaticContact CG-CD2 3.73Å; F57-F355 HydrophobicContact CG-CD2 3.73Å; F57-F355 HydrophobicContact CG-CE2 4.36Å; F57-L358 HydrophobicContact CD2-CD1 4.1Å; F57-L358 HydrophobicContact CE2-CD1 4Å
58I92.3Very high92.5Very high8 Ų846.7 Ų46.74%0.04123%0.231CC..EExtended strand (participates in β ladder)trans-87.8-66.1-177.7-56.1175.8000109.6T56 D76 K78 C79 L98 D100 L351T56-I58 PolarHBondContact O-N 2.94Å; I58-D76 HydrophobicContact CG2-CB 4.49Å; I58-D76 WeakPolarHBondContact CG2-OD2 3.3Å; I58-K78 HydrophobicContact CD1-CB 4.32Å; I58-C79 HydrophobicContact CD1-CB 3.56Å; I58-L98 HydrophobicContact CB-CB 4.22Å; I58-L98 WeakPolarHBondContact CB-O 3.44Å; I58-L98 PolarHBondContact N-O 3.36Å; I58-D100 HydrophobicContact CD1-CB 4.28Å; I58-D100 HydrophobicContact CG1-CB 4.47Å; I58-L351 WeakPolarHBondContact O-CD1 3.23Å
59I92Very high92.7Very high79 Ų7942.9 Ų42.941%0.40521%0.211SC..EExtended strand (participates in β ladder)trans-166.5164.5-175.5-164.9162.5000111.6F57 P61 L98F57-I59 WeakPolarHBondContact CE2-O 3.19Å; I59-P61 HydrophobicContact CG2-CG 4.13Å; I59-P61 WeakPolarHBondContact O-CD 3.34Å; I59-L98 HydrophobicContact CG2-CB 4.34Å; I59-L98 HydrophobicContact CG2-CD1 3.91Å; I59-L98 HydrophobicContact CG2-CG 4.41Å; I59-L98 PolarHBondContact O-N 2.82Å
60K93.9Very high92.8Very high45 Ų4542.3 Ų42.320%0.19621%0.208CC..  trans-108.495.8165.6-174.4-162.5-176.9-179.90110.5F57 S95 C96 F97 N354F57-K60 HydrophobicContact CZ-CB 4.28Å; K60-S95 WeakPolarHBondContact CE-OG 3.49Å; K60-S95 PolarHBondContact NZ-OG 3.4Å; K60-S95 VanDerWaalsContact NZ-OG 3.16Å; K60-C96 WeakPolarHBondContact CA-O 3.4Å; K60-C96 WeakPolarHBondContact CG-O 3.28Å; K60-F97 HydrophobicContact CB-CD1 3.97Å; K60-F97 HydrophobicContact CB-CE1 4.15Å; K60-F97 HydrophobicContact CD-CD1 4.3Å; K60-F97 HydrophobicContact CD-CE1 3.67Å; K60-F97 HydrophobicContact CD-CZ 4.18Å; K60-F97 HydrophobicContact CG-CD1 3.75Å; K60-F97 HydrophobicContact CG-CE1 3.64Å; K60-F97 HydrophobicContact CG-CZ 4.33Å; K60-N354 HydrophobicContact CB-CB 3.89Å; K60-N354 HydrophobicContact CD-CB 4.11Å; K60-N354 WeakPolarHBondContact CD-OD1 3.38Å
61P93.1Very high92.8Very high19 Ų1946.2 Ų46.212%0.12322%0.223CC..  trans-62.7142177.1-2233.4000112.6I59 V63 C96 L98I59-P61 HydrophobicContact CG2-CG 4.13Å; I59-P61 WeakPolarHBondContact O-CD 3.34Å; P61-V63 VanDerWaalsContact C-N 3.35Å; P61-V63 HydrophobicContact CB-CG1 4.14Å; P61-V63 HydrophobicContact CB-CG2 4.06Å; P61-V63 PolarHBondContact O-N 2.84Å; P61-V63 VanDerWaalsContact O-N 3.14Å; P61-C96 WeakPolarHBondContact CD-O 3.45Å; P61-L98 HydrophobicContact CG-CD1 3.51Å; P61-L98 HydrophobicContact CG-CG 3.77Å
62K91.8Very high92.8Very high187 Ų18747.4 Ų47.481%0.81323%0.231SC*.  trans-86.476.2174.7-66.9172.9-176.4165.90109.3
63V93.8Very high92.8Very high34 Ų3444 Ų4421%0.20622%0.216CC..  trans-135.1147.7-176.8-60.20000111P61 D68 C69 I93 C96P61-V63 VanDerWaalsContact C-N 3.35Å; P61-V63 HydrophobicContact CB-CG1 4.14Å; P61-V63 HydrophobicContact CB-CG2 4.06Å; P61-V63 PolarHBondContact O-N 2.84Å; P61-V63 VanDerWaalsContact O-N 3.14Å; V63-D68 HydrophobicContact CB-CB 4.17Å; V63-D68 HydrophobicContact CG1-CB 4.24Å; V63-C69 HydrophobicContact CG2-CB 3.94Å; V63-I93 HydrophobicContact CG2-CD1 4.35Å; V63-C96 HydrophobicContact CG2-CB 3.68Å
64E92Very high92.9Very high166 Ų16641.3 Ų41.378%0.77621%0.207SC*.SBendtrans-110-3.5-173.4-59.7-176.8166.700113.5M92 I93E64-M92 WeakPolarHBondContact O-CA 3.36Å; E64-I93 PolarHBondContact O-N 2.9Å
65S93.1Very high92.7Very high38 Ų3849.1 Ų49.127%0.26624%0.24SC..BIsolated β-bridgetrans-122.3139.4-175.51670000111.3N67 D68 C69S65-N67 VanDerWaalsContact C-N 3.32Å; S65-N67 PolarHBondContact O-N 3.04Å; S65-N67 PolarHBondContact OG-N 2.92Å; S65-D68 WeakPolarHBondContact CB-OD2 2.94Å; S65-D68 PolarHBondContact O-N 3.17Å; S65-C69 PolarHBondContact O-N 3.14Å; S65-C69 VanDerWaalsContact O-N 3.08Å
66T91.3Very high92.3Very high9 Ų950.4 Ų50.46%0.05525%0.247CC..Hα-helixtrans-52-47.6175.7-57.90000112.3D68 C69 I70 M84 G91 Y120T66-D68 VanDerWaalsContact C-N 3.29Å; T66-D68 PolarHBondContact O-N 3.24Å; T66-C69 WeakPolarHBondContact O-CB 3.48Å; T66-C69 PolarHBondContact O-N 2.99Å; T66-I70 HydrophobicContact CG2-CD1 4.12Å; T66-I70 WeakPolarHBondContact O-CG1 3.34Å; T66-I70 PolarHBondContact O-N 2.84Å; T66-I70 VanDerWaalsContact O-N 3.1Å; T66-M84 HydrophobicContact CG2-CE 3.99Å; T66-M84 HydrophobicContact CG2-SD 3.83Å; T66-G91 PolarHBondContact N-O 3.41Å; T66-G91 VanDerWaalsContact N-O 3.15Å; T66-G91 PolarHBondContact OG1-O 2.89Å; T66-Y120 HydrophobicContact CG2-CD2 4.27Å; T66-Y120 HydrophobicContact CG2-CE2 3.43Å; T66-Y120 VanDerWaalsContact CG2-CE2 3.43Å
67N91.6Very high92Very high75 Ų7553.9 Ų53.940%0.40127%0.269SS..Hα-helixtrans-67.6-31.2-176.6-67.9-1.4000112L33 S65 I70 R71L33-N67 HydrophobicContact CD1-CB 4.5Å; L33-N67 HydrophobicContact CD2-CB 4.29Å; S65-N67 VanDerWaalsContact C-N 3.32Å; S65-N67 PolarHBondContact O-N 3.04Å; S65-N67 PolarHBondContact OG-N 2.92Å; N67-I70 PolarHBondContact O-N 2.81Å; N67-R71 WeakPolarHBondContact O-CB 3.05Å; N67-R71 WeakPolarHBondContact O-CD 3.41Å; N67-R71 WeakPolarHBondContact O-CG 3.02Å; N67-R71 PolarHBondContact O-N 3.29Å
68D93Very high91.8Very high65 Ų6557.3 Ų57.335%0.34828%0.284SS..Hα-helixtrans-79.2-25.4178.5-62-37.2000112.3V63 S65 T66 R71 S72V63-D68 HydrophobicContact CB-CB 4.17Å; V63-D68 HydrophobicContact CG1-CB 4.24Å; S65-D68 WeakPolarHBondContact CB-OD2 2.94Å; S65-D68 PolarHBondContact O-N 3.17Å; T66-D68 VanDerWaalsContact C-N 3.29Å; T66-D68 PolarHBondContact O-N 3.24Å; D68-R71 IonicContact OD1-CZ 3.58Å; D68-R71 IonicContact OD1-NH1 3.73Å; D68-R71 PolarHBondContact OD1-NH1 3.38Å; D68-S72 WeakPolarHBondContact O-CB 3.44Å; D68-S72 PolarHBondContact O-N 2.03Å; D68-S72 PolarHBondContact O-OG 2.89Å
69C94.4Very high91.8Very high0 Ų057 Ų570%028%0.283CS..Hα-helixtrans-64.4-50.3166-175.20000111.3V63 S65 T66 R71 S72 C73 M84 I93 C96V63-C69 HydrophobicContact CG2-CB 3.94Å; S65-C69 PolarHBondContact O-N 3.14Å; S65-C69 VanDerWaalsContact O-N 3.08Å; T66-C69 WeakPolarHBondContact O-CB 3.48Å; T66-C69 PolarHBondContact O-N 2.99Å; C69-R71 PolarHBondContact O-N 3.09Å; C69-S72 WeakPolarHBondContact O-CA 3.3Å; C69-S72 VanDerWaalsContact O-CB 3.32Å; C69-S72 WeakPolarHBondContact O-CB 3.28Å; C69-S72 PolarHBondContact O-N 2.9Å; C69-C73 PolarHBondContact O-N 3.18Å; C69-M84 HydrophobicContact CB-CE 3.84Å; C69-M84 HydrophobicContact CB-CG 4.34Å; C69-M84 HydrophobicContact CB-SD 3.79Å; C69-I93 HydrophobicContact CB-CD1 3.78Å; C69-C96 WeakPolarHBondContact CA-SG 3.42Å; C69-C96 HydrophobicContact CB-CB 3.72Å; C69-C96 WeakPolarHBondContact CB-SG 3.43Å; C69-C96 WeakPolarHBondContact SG-CB 3.41Å; C69-C96 CovalentContact SG-SG 2.02Å; C69-C96 PolarHBondContact SG-SG 3.45Å
70I92.9Very high91.8Very high3 Ų353.5 Ų53.52%0.01527%0.265CS..Hα-helixtrans-65.2-42.4179-55.8161.3000110.7L33 F36 T66 N67 S72 C73 C74 M84 Y120L33-I70 HydrophobicContact CD2-CB 3.64Å; L33-I70 HydrophobicContact CD2-CD1 4Å; L33-I70 HydrophobicContact CD2-CG1 4.45Å; L33-I70 HydrophobicContact CD2-CG2 3.69Å; F36-I70 HydrophobicContact CB-CG2 4.09Å; F36-I70 HydrophobicContact CD1-CG2 4.32Å; F36-I70 HydrophobicContact CD2-CG2 3.57Å; F36-I70 HydrophobicContact CE2-CG2 4.03Å; F36-I70 HydrophobicContact CG-CG2 3.74Å; T66-I70 HydrophobicContact CG2-CD1 4.12Å; T66-I70 WeakPolarHBondContact O-CG1 3.34Å; T66-I70 PolarHBondContact O-N 2.84Å; T66-I70 VanDerWaalsContact O-N 3.1Å; N67-I70 PolarHBondContact O-N 2.81Å; I70-S72 PolarHBondContact O-N 2.74Å; I70-C73 CarbonylContact O-C 3.5Å; I70-C73 WeakPolarHBondContact O-CA 3.45Å; I70-C73 VanDerWaalsContact O-CB 3.23Å; I70-C73 WeakPolarHBondContact O-CB 3.49Å; I70-C73 PolarHBondContact O-N 2.92Å; I70-C74 PolarHBondContact O-N 2.96Å; I70-C74 PolarHBondContact O-SG 3.42Å; I70-M84 HydrophobicContact CD1-CE 4.44Å; I70-M84 HydrophobicContact CG1-CE 3.86Å; I70-Y120 HydrophobicContact CD1-CD1 3.48Å; I70-Y120 VanDerWaalsContact CD1-CD1 3.48Å; I70-Y120 HydrophobicContact CD1-CD2 4.17Å; I70-Y120 HydrophobicContact CD1-CE1 3.66Å; I70-Y120 HydrophobicContact CD1-CE2 4.35Å; I70-Y120 HydrophobicContact CD1-CG 3.74Å; I70-Y120 HydrophobicContact CG1-CD1 4.31Å; I70-Y120 HydrophobicContact CG1-CG 4.13Å
71R92.6Very high91.8Very high82 Ų8251.4 Ų51.431%0.30926%0.256SS..Hα-helixtrans-60.1-26171.9-73.9165.7-178.7155.3-2.2113.6L33 N67 D68 C69 K75L33-R71 HydrophobicContact CD1-CG 4.38Å; L33-R71 HydrophobicContact CG-CG 4.42Å; N67-R71 WeakPolarHBondContact O-CB 3.05Å; N67-R71 WeakPolarHBondContact O-CD 3.41Å; N67-R71 WeakPolarHBondContact O-CG 3.02Å; N67-R71 PolarHBondContact O-N 3.29Å; D68-R71 IonicContact OD1-CZ 3.58Å; D68-R71 IonicContact OD1-NH1 3.73Å; D68-R71 PolarHBondContact OD1-NH1 3.38Å; C69-R71 PolarHBondContact O-N 3.09Å; R71-K75 WeakPolarHBondContact O-CG 3.27Å
72S93.3Very high91.8Very high24 Ų2450.5 Ų50.517%0.16825%0.25CS..Hα-helixtrans-75.4-39172.5-59.50000111D68 C69 I70 K75D68-S72 WeakPolarHBondContact O-CB 3.44Å; D68-S72 PolarHBondContact O-N 2.03Å; D68-S72 PolarHBondContact O-OG 2.89Å; C69-S72 WeakPolarHBondContact O-CA 3.3Å; C69-S72 VanDerWaalsContact O-CB 3.32Å; C69-S72 WeakPolarHBondContact O-CB 3.28Å; C69-S72 PolarHBondContact O-N 2.9Å; I70-S72 PolarHBondContact O-N 2.74Å; S72-K75 PolarHBondContact O-N 3.22Å
73C93.4Very high91.8Very high0 Ų041.6 Ų41.60%021%0.211CC..Hα-helixtrans-59.2-46.4169.8-164.80000111.5F36 C69 I70 K75 D76 C79 A82 L98F36-C73 HydrophobicContact CZ-CB 4.13Å; F36-C73 WeakPolarHBondContact CZ-SG 3.48Å; C69-C73 PolarHBondContact O-N 3.18Å; I70-C73 CarbonylContact O-C 3.5Å; I70-C73 WeakPolarHBondContact O-CA 3.45Å; I70-C73 VanDerWaalsContact O-CB 3.23Å; I70-C73 WeakPolarHBondContact O-CB 3.49Å; I70-C73 PolarHBondContact O-N 2.92Å; C73-K75 PolarHBondContact O-N 2.85Å; C73-D76 PolarHBondContact O-N 2.84Å; C73-D76 VanDerWaalsContact O-O 3.12Å; C73-C79 WeakPolarHBondContact CA-SG 3.27Å; C73-C79 HydrophobicContact CB-CB 3.98Å; C73-C79 WeakPolarHBondContact CB-SG 3.46Å; C73-C79 WeakPolarHBondContact O-CB 3.48Å; C73-C79 VanDerWaalsContact SG-C 3.51Å; C73-C79 WeakPolarHBondContact SG-CB 3.44Å; C73-C79 CovalentContact SG-SG 2.03Å; C73-C79 PolarHBondContact SG-SG 3.34Å; C73-A82 HydrophobicContact CB-CB 4.31Å; C73-L98 HydrophobicContact CB-CD1 4.35Å; C73-L98 HydrophobicContact CB-CD2 3.75Å
74C90.6Very high91.8Very high10 Ų1040 Ų407%0.06820%0.202CC..THydrogen-bonded Turntrans-55.9-18.4176.9-69.90000115.7F28 C32 I70F28-C74 WeakPolarHBondContact CE1-O 3.45Å; C32-C74 HydrophobicContact CB-CB 3.75Å; C32-C74 WeakPolarHBondContact CB-SG 3.13Å; C32-C74 VanDerWaalsContact SG-CA 3.58Å; C32-C74 WeakPolarHBondContact SG-CB 3.25Å; C32-C74 CovalentContact SG-SG 2.03Å; C32-C74 PolarHBondContact SG-SG 2.77Å; I70-C74 PolarHBondContact O-N 2.96Å; I70-C74 PolarHBondContact O-SG 3.42Å
75K88.7Confident91.8Very high169 Ų16935 Ų3574%0.73518%0.179SC*.THydrogen-bonded Turntrans-84.6-22.7177.2-68.2169.2-173.9175.30113.4R71 S72 C73R71-K75 WeakPolarHBondContact O-CG 3.27Å; S72-K75 PolarHBondContact O-N 3.22Å; C73-K75 PolarHBondContact O-N 2.85Å
76D87.5Confident91.6Very high26 Ų2635.6 Ų35.614%0.13918%0.179CC..SBendtrans-101.9120.4177.4-163.3-47.5000109.9I58 C73 K78 C79 R329I58-D76 HydrophobicContact CG2-CB 4.49Å; I58-D76 WeakPolarHBondContact CG2-OD2 3.3Å; C73-D76 PolarHBondContact O-N 2.84Å; C73-D76 VanDerWaalsContact O-O 3.12Å; D76-K78 PolarHBondContact O-N 3.36Å; D76-K78 VanDerWaalsContact O-N 3.15Å; D76-K78 WeakPolarHBondContact OD1-CB 3.3Å; D76-K78 PolarHBondContact OD1-N 3.05Å; D76-C79 HydrophobicContact CB-CB 4.07Å; D76-C79 PolarHBondContact O-N 3.4Å; D76-R329 IonicContact OD1-NH1 2.77Å; D76-R329 IonicContact OD1-NH2 2.67Å; D76-R329 IonicContact OD2-CZ 3.08Å; D76-R329 IonicContact OD2-NH1 3.25Å; D76-R329 IonicContact OD2-NH2 2.79Å; D76-R329 PolarHBondContact OD2-NH2 2.82Å
77P87Confident91.4Very high91 Ų9136.3 Ų36.359%0.59119%0.187SC*.THydrogen-bonded Turntrans-64.5-17.6-179.226.9-35.4000113.8
78K88.9Confident90.8Very high73 Ų7339.1 Ų39.132%0.31721%0.213SC..THydrogen-bonded Turntrans-84.3-15172.8-71.7-166.4168.9-158.70113.5I58 D76 N80 D100 E274I58-K78 HydrophobicContact CD1-CB 4.32Å; D76-K78 PolarHBondContact O-N 3.36Å; D76-K78 VanDerWaalsContact O-N 3.15Å; D76-K78 WeakPolarHBondContact OD1-CB 3.3Å; D76-K78 PolarHBondContact OD1-N 3.05Å; K78-N80 PolarHBondContact O-N 2.8Å; K78-N80 PolarHBondContact O-ND2 2.98Å; K78-D100 HydrophobicContact CB-CB 4.13Å; K78-D100 WeakPolarHBondContact O-CB 3.48Å; K78-D100 VanDerWaalsContact O-CG 3.29Å; K78-E274 IonicContact NZ-OE1 2.67Å
79C93.1Very high89.9Confident1 Ų137.5 Ų37.51%0.00721%0.212CC..  trans-79.2119.8-174-1690000112.1I58 C73 D76 R122I58-C79 HydrophobicContact CD1-CB 3.56Å; C73-C79 WeakPolarHBondContact CA-SG 3.27Å; C73-C79 HydrophobicContact CB-CB 3.98Å; C73-C79 WeakPolarHBondContact CB-SG 3.46Å; C73-C79 WeakPolarHBondContact O-CB 3.48Å; C73-C79 VanDerWaalsContact SG-C 3.51Å; C73-C79 WeakPolarHBondContact SG-CB 3.44Å; C73-C79 CovalentContact SG-SG 2.03Å; C73-C79 PolarHBondContact SG-SG 3.34Å; D76-C79 HydrophobicContact CB-CB 4.07Å; D76-C79 PolarHBondContact O-N 3.4Å; C79-R122 PolarHBondContact O-NE 2.84Å; C79-R122 PolarHBondContact O-NH2 2.94Å; C79-R122 VanDerWaalsContact O-NH2 3.11Å
80N91.9Very high89.1Confident7 Ų747.2 Ų47.24%0.03726%0.257CS..  trans-128.7-15.4179.948.844.7000113K78 F99 D100 C101 I121 R122 V125K78-N80 PolarHBondContact O-N 2.8Å; K78-N80 PolarHBondContact O-ND2 2.98Å; N80-F99 PolarHBondContact N-O 2.77Å; N80-F99 PolarHBondContact OD1-O 3.42Å; N80-D100 PolarHBondContact ND2-OD1 3.41Å; N80-C101 PolarHBondContact ND2-N 3.07Å; N80-C101 WeakPolarHBondContact OD1-CB 3.09Å; N80-C101 PolarHBondContact OD1-N 3.12Å; N80-I121 WeakPolarHBondContact O-CA 3.25Å; N80-R122 HydrophobicContact CB-CB 4.28Å; N80-R122 PolarHBondContact O-N 2.9Å; N80-V125 HydrophobicContact CB-CG2 3.81Å
81V93Very high88.4Confident0 Ų049.2 Ų49.20%028%0.279CS..EExtended strand (participates in β ladder)trans-129.5129.5173.1174.90000111F99 C101 Y107 F111 Y120 I121V81-F99 HydrophobicContact CB-CB 4.4Å; V81-F99 PolarHBondContact N-O 2.78Å; V81-F99 PolarHBondContact O-N 3.01Å; V81-C101 VanDerWaalsContact CB-SG 3.58Å; V81-C101 HydrophobicContact CG2-CB 3.84Å; V81-C101 WeakPolarHBondContact CG2-SG 3.35Å; V81-Y107 HydrophobicContact CG2-CE2 4.42Å; V81-F111 HydrophobicContact CG1-CZ 3.88Å; V81-Y120 WeakPolarHBondContact CA-O 3.22Å; V81-I121 HydrophobicContact CG2-CG1 4.12Å; V81-I121 HydrophobicContact CG2-CG2 4.16Å
82A94.1Very high88.2Confident0 Ų051 Ų510%029%0.292CS..EExtended strand (participates in β ladder)trans-123.2114.6171.500000109.2C73 M84 F97 L98 Y120C73-A82 HydrophobicContact CB-CB 4.31Å; A82-M84 HydrophobicContact CB-CE 4.16Å; A82-F97 WeakPolarHBondContact CA-O 3.13Å; A82-L98 HydrophobicContact CB-CD2 3.63Å; A82-Y120 PolarHBondContact N-O 3.34Å; A82-Y120 PolarHBondContact O-N 3.37Å
83F91.9Very high88.2Confident0 Ų050.4 Ų50.40%029%0.286CS..EExtended strand (participates in β ladder)trans-118.4151.9174.478.1-94.8000112.2V44 L45 F97 F99 F117 L118 N119 L358V44-F83 HydrophobicContact CG2-CD2 4.25Å; V44-F83 HydrophobicContact CG2-CE2 3.99Å; L45-F83 HydrophobicContact CB-CD1 3.69Å; L45-F83 HydrophobicContact CB-CE1 3.45Å; L45-F83 VanDerWaalsContact CB-CE1 3.45Å; L45-F83 HydrophobicContact CB-CG 4.34Å; L45-F83 HydrophobicContact CB-CZ 3.95Å; L45-F83 HydrophobicContact CD2-CD1 4.2Å; L45-F83 HydrophobicContact CD2-CE1 3.66Å; L45-F83 HydrophobicContact CG-CE1 4.19Å; F83-F97 HydrophobicContact CD1-CB 4.27Å; F83-F97 HydrophobicContact CD2-CB 4.47Å; F83-F97 HydrophobicContact CD2-CD2 4.17Å; F83-F97 HydrophobicContact CE1-CB 3.9Å; F83-F97 HydrophobicContact CE2-CB 4.1Å; F83-F97 AromaticContact CE2-CD2 3.69Å; F83-F97 HydrophobicContact CE2-CD2 3.69Å; F83-F97 HydrophobicContact CE2-CE2 4.43Å; F83-F97 HydrophobicContact CE2-CG 4.15Å; F83-F97 HydrophobicContact CZ-CB 3.8Å; F83-F97 HydrophobicContact CZ-CD2 4.14Å; F83-F97 HydrophobicContact CZ-CG 4.12Å; F83-F97 PolarHBondContact N-O 3.41Å; F83-F97 PolarHBondContact O-N 3.4Å; F83-F99 HydrophobicContact CD1-CD2 4.19Å; F83-F99 HydrophobicContact CD1-CE2 4.42Å; F83-F99 AromaticContact CE1-CD2 3.6Å; F83-F99 HydrophobicContact CE1-CD2 3.6Å; F83-F99 AromaticContact CE1-CE2 3.42Å; F83-F99 HydrophobicContact CE1-CE2 3.42Å; F83-F99 VanDerWaalsContact CE1-CE2 3.42Å; F83-F99 HydrophobicContact CE1-CZ 4.35Å; F83-F99 HydrophobicContact CZ-CE2 4.03Å; F83-F117 HydrophobicContact CD2-CD1 4.43Å; F83-L118 CarbonylContact C-O 3.57Å; F83-L118 VanDerWaalsContact CA-O 3.29Å; F83-L118 WeakPolarHBondContact CA-O 3.33Å; F83-L118 WeakPolarHBondContact CB-O 3.43Å; F83-N119 HydrophobicContact CB-CB 4.08Å; F83-L358 HydrophobicContact CE2-CD2 3.93Å; F83-L358 HydrophobicContact CZ-CD1 4.2Å; F83-L358 HydrophobicContact CZ-CD2 3.61Å
84M92.8Very high88.1Confident0 Ų055.9 Ų55.90%031%0.31CS..EExtended strand (participates in β ladder)trans-144.3146-160-53.7171.7-141.800110.5T66 C69 I70 A82 I93 S95 F117 L118 Y120T66-M84 HydrophobicContact CG2-CE 3.99Å; T66-M84 HydrophobicContact CG2-SD 3.83Å; C69-M84 HydrophobicContact CB-CE 3.84Å; C69-M84 HydrophobicContact CB-CG 4.34Å; C69-M84 HydrophobicContact CB-SD 3.79Å; I70-M84 HydrophobicContact CD1-CE 4.44Å; I70-M84 HydrophobicContact CG1-CE 3.86Å; A82-M84 HydrophobicContact CB-CE 4.16Å; M84-I93 HydrophobicContact CB-CB 4.26Å; M84-I93 HydrophobicContact CB-CD1 4.23Å; M84-I93 HydrophobicContact CB-CG2 3.87Å; M84-I93 HydrophobicContact CG-CD1 3.95Å; M84-I93 HydrophobicContact CG-CG2 4.4Å; M84-I93 HydrophobicContact SD-CD1 3.75Å; M84-I93 HydrophobicContact SD-CG2 3.97Å; M84-S95 VanDerWaalsContact CA-O 3.23Å; M84-S95 WeakPolarHBondContact CA-O 3.26Å; M84-F117 WeakPolarHBondContact O-CA 3.1Å; M84-L118 PolarHBondContact N-O 2.92Å; M84-L118 PolarHBondContact O-N 2.8Å; M84-Y120 HydrophobicContact CE-CD2 3.47Å; M84-Y120 VanDerWaalsContact CE-CD2 3.47Å; M84-Y120 HydrophobicContact CE-CE2 4.03Å; M84-Y120 HydrophobicContact CE-CG 4.21Å
85E92.4Very high88.1Confident63 Ų6356.3 Ų56.329%0.29431%0.313SS..EExtended strand (participates in β ladder)trans-93.3129.2169.7-168-162.1159.400109.6G87 I93 K94 S95 F117E85-G87 PolarHBondContact O-N 2.99Å; E85-I93 CarbonylContact O-C 3.56Å; E85-I93 WeakPolarHBondContact O-CA 3.49Å; E85-K94 HydrophobicContact CB-CB 4.38Å; E85-K94 PolarHBondContact O-N 2.77Å; E85-K94 IonicContact OE1-NZ 3.05Å; E85-K94 PolarHBondContact OE1-NZ 2.94Å; E85-S95 PolarHBondContact N-O 2.62Å; E85-S95 VanDerWaalsContact N-O 3.08Å; E85-F117 HydrophobicContact CB-CD1 4.39Å; E85-F117 HydrophobicContact CB-CE1 4.05Å; E85-F117 HydrophobicContact CG-CE1 4.2Å; E85-F117 HydrophobicContact CG-CZ 4.18Å
86N89.4Confident88.4Confident50 Ų5048.3 Ų48.327%0.26728%0.279SS..EExtended strand (participates in β ladder)trans-62.1130.5-178.6-82.3-12.4000112.6K94 G116 L118N86-K94 PolarHBondContact O-NZ 2.79Å; N86-G116 PolarHBondContact N-O 3.29Å; N86-L118 WeakPolarHBondContact OD1-CD1 3.34Å; N86-L118 WeakPolarHBondContact OD1-CG 3.29Å
87G86.9Confident88.8Confident23 Ų2347.3 Ų47.324%0.23727%0.273CS..  trans-81.4-172.3170.700000112.9E85 G89 M92E85-G87 PolarHBondContact O-N 2.99Å; G87-G89 VanDerWaalsContact C-N 3.31Å; G87-G89 PolarHBondContact O-N 3.49Å; G87-M92 VanDerWaalsContact CA-O 3.3Å; G87-M92 WeakPolarHBondContact CA-O 3.32Å; G87-M92 PolarHBondContact N-O 3.23Å
88S78.2Confident89.2Confident134 Ų13443.1 Ų43.194%0.93725%0.246SC*.SBendtrans-850.7-176.3-47.50000114.3
89G75.5Confident89.5Confident31 Ų3139.6 Ų39.632%0.3223%0.23SC..SBendtrans-142.3159-175.400000111.7G87 G91 M92G87-G89 VanDerWaalsContact C-N 3.31Å; G87-G89 PolarHBondContact O-N 3.49Å; G89-G91 PolarHBondContact O-N 2.86Å; G89-M92 WeakPolarHBondContact O-CB 3.46Å; G89-M92 PolarHBondContact O-N 2.92Å; G89-M92 VanDerWaalsContact O-N 3.08Å
90E76.8Confident89.5Confident205 Ų20540.5 Ų40.596%0.95824%0.235SC*.THydrogen-bonded Turntrans-62.3125.9-178.3-169.7170.6-164.100111.1M92E90-M92 PolarHBondContact O-N 3.39Å
91G78.1Confident89.6Confident45 Ų4540.1 Ų40.146%0.46423%0.233SC..THydrogen-bonded Turntrans73.2-1.2-175.300000116T66 G89T66-G91 PolarHBondContact N-O 3.41Å; T66-G91 VanDerWaalsContact N-O 3.15Å; T66-G91 PolarHBondContact OG1-O 2.89Å; G89-G91 PolarHBondContact O-N 2.86Å
92M88.4Confident89.4Confident120 Ų12042.9 Ų42.959%0.59125%0.248SC*.BIsolated β-bridgetrans-89.8140.9174.6-65.4-177.7171.400111.4E64 G87 G89 E90E64-M92 WeakPolarHBondContact O-CA 3.36Å; G87-M92 VanDerWaalsContact CA-O 3.3Å; G87-M92 WeakPolarHBondContact CA-O 3.32Å; G87-M92 PolarHBondContact N-O 3.23Å; G89-M92 WeakPolarHBondContact O-CB 3.46Å; G89-M92 PolarHBondContact O-N 2.92Å; G89-M92 VanDerWaalsContact O-N 3.08Å; E90-M92 PolarHBondContact O-N 3.39Å
93I92.6Very high89.3Confident10 Ų1044.4 Ų44.45%0.05125%0.254CS..EExtended strand (participates in β ladder)trans-127.1146.8-179.561.8173.6000110.9V63 E64 C69 M84 E85 C96V63-I93 HydrophobicContact CG2-CD1 4.35Å; E64-I93 PolarHBondContact O-N 2.9Å; C69-I93 HydrophobicContact CB-CD1 3.78Å; M84-I93 HydrophobicContact CB-CB 4.26Å; M84-I93 HydrophobicContact CB-CD1 4.23Å; M84-I93 HydrophobicContact CB-CG2 3.87Å; M84-I93 HydrophobicContact CG-CD1 3.95Å; M84-I93 HydrophobicContact CG-CG2 4.4Å; M84-I93 HydrophobicContact SD-CD1 3.75Å; M84-I93 HydrophobicContact SD-CG2 3.97Å; E85-I93 CarbonylContact O-C 3.56Å; E85-I93 WeakPolarHBondContact O-CA 3.49Å; I93-C96 HydrophobicContact CD1-CB 3.88Å
94K91.4Very high89.2Confident116 Ų11646.3 Ų46.350%0.50426%0.262SS..EExtended strand (participates in β ladder)trans-84.6-25.9175.1-52.8-161.9-16179.70113E85 N86E85-K94 HydrophobicContact CB-CB 4.38Å; E85-K94 PolarHBondContact O-N 2.77Å; E85-K94 IonicContact OE1-NZ 3.05Å; E85-K94 PolarHBondContact OE1-NZ 2.94Å; N86-K94 PolarHBondContact O-NZ 2.79Å
95S92.5Very high88.7Confident19 Ų1951.6 Ų51.613%0.13329%0.287CS..EExtended strand (participates in β ladder)trans-160.8148.6-178.2-800000110K60 M84 E85K60-S95 WeakPolarHBondContact CE-OG 3.49Å; K60-S95 PolarHBondContact NZ-OG 3.4Å; K60-S95 VanDerWaalsContact NZ-OG 3.16Å; M84-S95 VanDerWaalsContact CA-O 3.23Å; M84-S95 WeakPolarHBondContact CA-O 3.26Å; E85-S95 PolarHBondContact N-O 2.62Å; E85-S95 VanDerWaalsContact N-O 3.08Å
96C95Very high88.3Confident0 Ų051.8 Ų51.80%029%0.287CS..EExtended strand (participates in β ladder)trans-125.5131.8179.6167.60000108K60 P61 V63 C69 I93K60-C96 WeakPolarHBondContact CA-O 3.4Å; K60-C96 WeakPolarHBondContact CG-O 3.28Å; P61-C96 WeakPolarHBondContact CD-O 3.45Å; V63-C96 HydrophobicContact CG2-CB 3.68Å; C69-C96 WeakPolarHBondContact CA-SG 3.42Å; C69-C96 HydrophobicContact CB-CB 3.72Å; C69-C96 WeakPolarHBondContact CB-SG 3.43Å; C69-C96 WeakPolarHBondContact SG-CB 3.41Å; C69-C96 CovalentContact SG-SG 2.02Å; C69-C96 PolarHBondContact SG-SG 3.45Å; I93-C96 HydrophobicContact CD1-CB 3.88Å
97F94.9Very high88.1Confident5 Ų550.7 Ų50.72%0.02228%0.28CS..EExtended strand (participates in β ladder)trans-130.7132.4178-58-86.4000109.9F57 K60 A82 F83 F99 I357 L358F57-F97 HydrophobicContact CE2-CD1 4.24Å; K60-F97 HydrophobicContact CB-CD1 3.97Å; K60-F97 HydrophobicContact CB-CE1 4.15Å; K60-F97 HydrophobicContact CD-CD1 4.3Å; K60-F97 HydrophobicContact CD-CE1 3.67Å; K60-F97 HydrophobicContact CD-CZ 4.18Å; K60-F97 HydrophobicContact CG-CD1 3.75Å; K60-F97 HydrophobicContact CG-CE1 3.64Å; K60-F97 HydrophobicContact CG-CZ 4.33Å; A82-F97 WeakPolarHBondContact CA-O 3.13Å; F83-F97 HydrophobicContact CD1-CB 4.27Å; F83-F97 HydrophobicContact CD2-CB 4.47Å; F83-F97 HydrophobicContact CD2-CD2 4.17Å; F83-F97 HydrophobicContact CE1-CB 3.9Å; F83-F97 HydrophobicContact CE2-CB 4.1Å; F83-F97 AromaticContact CE2-CD2 3.69Å; F83-F97 HydrophobicContact CE2-CD2 3.69Å; F83-F97 HydrophobicContact CE2-CE2 4.43Å; F83-F97 HydrophobicContact CE2-CG 4.15Å; F83-F97 HydrophobicContact CZ-CB 3.8Å; F83-F97 HydrophobicContact CZ-CD2 4.14Å; F83-F97 HydrophobicContact CZ-CG 4.12Å; F83-F97 PolarHBondContact N-O 3.41Å; F83-F97 PolarHBondContact O-N 3.4Å; F97-F99 HydrophobicContact CB-CE2 4.29Å; F97-I357 HydrophobicContact CZ-CG2 4.4Å; F97-L358 HydrophobicContact CB-CD1 4.43Å; F97-L358 HydrophobicContact CD1-CD1 3.77Å; F97-L358 HydrophobicContact CD1-CD2 3.59Å; F97-L358 HydrophobicContact CD1-CG 3.88Å; F97-L358 HydrophobicContact CD2-CD2 3.87Å; F97-L358 HydrophobicContact CE1-CD1 4.25Å; F97-L358 HydrophobicContact CE1-CD2 3.51Å; F97-L358 HydrophobicContact CE1-CG 3.86Å; F97-L358 HydrophobicContact CE2-CD2 3.8Å; F97-L358 HydrophobicContact CG-CD1 4.23Å; F97-L358 HydrophobicContact CG-CD2 3.76Å; F97-L358 HydrophobicContact CG-CG 4.44Å; F97-L358 HydrophobicContact CZ-CD2 3.61Å; F97-L358 HydrophobicContact CZ-CG 4.41Å
98L95.3Very high88.1Confident3 Ų350.5 Ų50.52%0.01627%0.274CS..EExtended strand (participates in β ladder)trans-113132.2-174.7-59.4-172.7000110.6I58 I59 P61 C73 A82I58-L98 HydrophobicContact CB-CB 4.22Å; I58-L98 WeakPolarHBondContact CB-O 3.44Å; I58-L98 PolarHBondContact N-O 3.36Å; I59-L98 HydrophobicContact CG2-CB 4.34Å; I59-L98 HydrophobicContact CG2-CD1 3.91Å; I59-L98 HydrophobicContact CG2-CG 4.41Å; I59-L98 PolarHBondContact O-N 2.82Å; P61-L98 HydrophobicContact CG-CD1 3.51Å; P61-L98 HydrophobicContact CG-CG 3.77Å; C73-L98 HydrophobicContact CB-CD1 4.35Å; C73-L98 HydrophobicContact CB-CD2 3.75Å; A82-L98 HydrophobicContact CB-CD2 3.63Å
99F95.1Very high88.6Confident0 Ų044.7 Ų44.70%023%0.233CC..EExtended strand (participates in β ladder)trans-131.6148.8-177.2-84.2-100.4000112L45 T47 V51 F57 N80 V81 F83 F97 L358L45-F99 HydrophobicContact CD2-CB 4.47Å; L45-F99 HydrophobicContact CD2-CD1 3.69Å; L45-F99 HydrophobicContact CD2-CD2 3.85Å; L45-F99 HydrophobicContact CD2-CE1 3.77Å; L45-F99 HydrophobicContact CD2-CE2 3.95Å; L45-F99 HydrophobicContact CD2-CG 3.73Å; L45-F99 HydrophobicContact CD2-CZ 3.9Å; T47-F99 HydrophobicContact CG2-CE1 4.15Å; T47-F99 HydrophobicContact CG2-CZ 3.83Å; V51-F99 HydrophobicContact CG2-CE1 4.16Å; F57-F99 HydrophobicContact CB-CD1 4.37Å; F57-F99 HydrophobicContact CB-CE1 3.74Å; F57-F99 HydrophobicContact CB-CZ 3.82Å; F57-F99 HydrophobicContact CD2-CD2 4.12Å; F57-F99 HydrophobicContact CD2-CE1 4.27Å; F57-F99 AromaticContact CD2-CE2 3.49Å; F57-F99 HydrophobicContact CD2-CE2 3.49Å; F57-F99 VanDerWaalsContact CD2-CE2 3.49Å; F57-F99 AromaticContact CD2-CZ 3.59Å; F57-F99 HydrophobicContact CD2-CZ 3.59Å; F57-F99 HydrophobicContact CE2-CE2 4.16Å; F57-F99 HydrophobicContact CG-CE1 4.46Å; F57-F99 HydrophobicContact CG-CE2 4.39Å; F57-F99 HydrophobicContact CG-CZ 4.05Å; N80-F99 PolarHBondContact N-O 2.77Å; N80-F99 PolarHBondContact OD1-O 3.42Å; V81-F99 HydrophobicContact CB-CB 4.4Å; V81-F99 PolarHBondContact N-O 2.78Å; V81-F99 PolarHBondContact O-N 3.01Å; F83-F99 HydrophobicContact CD1-CD2 4.19Å; F83-F99 HydrophobicContact CD1-CE2 4.42Å; F83-F99 AromaticContact CE1-CD2 3.6Å; F83-F99 HydrophobicContact CE1-CD2 3.6Å; F83-F99 AromaticContact CE1-CE2 3.42Å; F83-F99 HydrophobicContact CE1-CE2 3.42Å; F83-F99 VanDerWaalsContact CE1-CE2 3.42Å; F83-F99 HydrophobicContact CE1-CZ 4.35Å; F83-F99 HydrophobicContact CZ-CE2 4.03Å; F97-F99 HydrophobicContact CB-CE2 4.29Å; F99-L358 HydrophobicContact CE2-CD1 3.57Å; F99-L358 HydrophobicContact CZ-CD1 3.56Å
100D93.7Very high89.1Confident19 Ų1944.4 Ų44.410%0.10222%0.222CC..EExtended strand (participates in β ladder)trans-97.2113156.2-172.7-3.3000107.9A55 T56 I58 K78 N80 L102A55-D100 CarbonylContact C-O 3.5Å; A55-D100 WeakPolarHBondContact CA-O 3.39Å; A55-D100 WeakPolarHBondContact CB-O 3.34Å; T56-D100 PolarHBondContact N-O 3.38Å; T56-D100 PolarHBondContact O-N 3.48Å; I58-D100 HydrophobicContact CD1-CB 4.28Å; I58-D100 HydrophobicContact CG1-CB 4.47Å; K78-D100 HydrophobicContact CB-CB 4.13Å; K78-D100 WeakPolarHBondContact O-CB 3.48Å; K78-D100 VanDerWaalsContact O-CG 3.29Å; N80-D100 PolarHBondContact ND2-OD1 3.41Å; D100-L102 PolarHBondContact OD1-N 2.96Å
101C92.8Very high89.6Confident0 Ų035.1 Ų35.10%018%0.179CC..  trans-101.19-179.3-71.60000113.4N80 V81 Y107 V108 C109N80-C101 PolarHBondContact ND2-N 3.07Å; N80-C101 WeakPolarHBondContact OD1-CB 3.09Å; N80-C101 PolarHBondContact OD1-N 3.12Å; V81-C101 VanDerWaalsContact CB-SG 3.58Å; V81-C101 HydrophobicContact CG2-CB 3.84Å; V81-C101 WeakPolarHBondContact CG2-SG 3.35Å; C101-Y107 HydrophobicContact CB-CD2 3.93Å; C101-Y107 HydrophobicContact CB-CE2 3.46Å; C101-Y107 VanDerWaalsContact CB-CE2 3.46Å; C101-Y107 WeakPolarHBondContact O-CD2 3.38Å; C101-V108 WeakPolarHBondContact O-CG2 3.29Å; C101-V108 PolarHBondContact O-N 2.81Å; C101-C109 WeakPolarHBondContact CA-SG 2.92Å; C101-C109 HydrophobicContact CB-CB 3.46Å; C101-C109 VanDerWaalsContact CB-CB 3.46Å; C101-C109 WeakPolarHBondContact CB-SG 3.2Å; C101-C109 WeakPolarHBondContact SG-CB 3.44Å; C101-C109 CovalentContact SG-SG 2.01Å; C101-C109 PolarHBondContact SG-SG 3.48Å
102L90.4Very high90.1Very high58 Ų5833.2 Ų33.230%0.30416%0.158SC..EExtended strand (participates in β ladder)trans-107.1109177.7-68.7177.2000110.7D100 Q106 Y107 V125D100-L102 PolarHBondContact OD1-N 2.96Å; L102-Q106 CarbonylContact C-O 3.55Å; L102-Q106 WeakPolarHBondContact CA-O 3.23Å; L102-Y107 HydrophobicContact CD2-CD2 4.47Å; L102-V125 HydrophobicContact CD1-CG2 3.84Å; L102-V125 HydrophobicContact CD2-CG1 3.98Å; L102-V125 HydrophobicContact CD2-CG2 4.16Å; L102-V125 HydrophobicContact CG-CG1 4.48Å; L102-V125 HydrophobicContact CG-CG2 4.1Å
103Y91Very high90Very high32 Ų3232 Ų3213%0.12515%0.147CC..EExtended strand (participates in β ladder)trans-96108.8166.1-168.9-102.8000109.3Q105 Q106 L280 E284Y103-Q105 PolarHBondContact O-N 3.29Å; Y103-Q106 PolarHBondContact N-O 2.74Å; Y103-Q106 WeakPolarHBondContact O-CB 3.39Å; Y103-Q106 PolarHBondContact O-N 2.89Å; Y103-L280 HydrophobicContact CD1-CD1 3.37Å; Y103-L280 HydrophobicContact CD1-CG 4.18Å; Y103-L280 HydrophobicContact CD2-CD1 4.31Å; Y103-L280 HydrophobicContact CE1-CB 4.23Å; Y103-L280 HydrophobicContact CE1-CD1 3.3Å; Y103-L280 HydrophobicContact CE1-CG 3.64Å; Y103-L280 HydrophobicContact CE2-CD1 4.28Å; Y103-L280 HydrophobicContact CE2-CG 4.15Å; Y103-L280 HydrophobicContact CG-CD1 3.89Å; Y103-L280 PolarHBondContact OH-N 3.17Å; Y103-E284 WeakPolarHBondContact CE1-OE2 3.25Å; Y103-E284 PolarHBondContact OH-OE2 2.89Å
104K89.4Confident89.9Confident40 Ų4034 Ų3417%0.17416%0.155CC..THydrogen-bonded Turntrans54.948175.3-69.6174.4172.7178.50113.2Q106 P149 D150 E284K104-Q106 PolarHBondContact O-N 3.28Å; K104-P149 HydrophobicContact CB-CB 3.85Å; K104-P149 WeakPolarHBondContact O-CA 3.33Å; K104-D150 HydrophobicContact CB-CB 3.92Å; K104-D150 WeakPolarHBondContact CD-O 3.37Å; K104-D150 HydrophobicContact CG-CB 4.41Å; K104-D150 PolarHBondContact O-N 3.13Å; K104-E284 IonicContact NZ-OE2 3.46Å; K104-E284 PolarHBondContact NZ-OE2 2.87Å
105Q83.8Confident89.8Confident111 Ų11136.2 Ų36.252%0.51917%0.165SC..THydrogen-bonded Turntrans65.9-1.8-172.2-61.1-170.28500116.2Y103 D150Y103-Q105 PolarHBondContact O-N 3.29Å; Q105-D150 WeakPolarHBondContact CG-OD2 3.4Å; Q105-D150 VanDerWaalsContact NE2-CG 3.27Å; Q105-D150 PolarHBondContact NE2-OD1 2.8Å; Q105-D150 PolarHBondContact NE2-OD2 2.67Å; Q105-D150 VanDerWaalsContact NE2-OD2 3.07Å
106Q83.5Confident89.7Confident66 Ų6636.6 Ų36.631%0.30817%0.172SC..EExtended strand (participates in β ladder)trans-90.6134.3172.9-174167.219.800111.1L102 Y103 K104 V108L102-Q106 CarbonylContact C-O 3.55Å; L102-Q106 WeakPolarHBondContact CA-O 3.23Å; Y103-Q106 PolarHBondContact N-O 2.74Å; Y103-Q106 WeakPolarHBondContact O-CB 3.39Å; Y103-Q106 PolarHBondContact O-N 2.89Å; K104-Q106 PolarHBondContact O-N 3.28Å; Q106-V108 HydrophobicContact CG-CG1 4.39Å
107Y85.4Confident89.5Confident28 Ų2837.5 Ų37.511%0.1118%0.176CC..EExtended strand (participates in β ladder)trans-72.5132.1170.5-169.4-105.2000111.6V81 C101 L102 C109 F111 V125 D129V81-Y107 HydrophobicContact CG2-CE2 4.42Å; C101-Y107 HydrophobicContact CB-CD2 3.93Å; C101-Y107 HydrophobicContact CB-CE2 3.46Å; C101-Y107 VanDerWaalsContact CB-CE2 3.46Å; C101-Y107 WeakPolarHBondContact O-CD2 3.38Å; L102-Y107 HydrophobicContact CD2-CD2 4.47Å; Y107-C109 HydrophobicContact CE1-CB 3.91Å; Y107-C109 WeakPolarHBondContact CE1-O 3.34Å; Y107-C109 HydrophobicContact CE2-CB 4.01Å; Y107-C109 WeakPolarHBondContact OH-CB 2.98Å; Y107-F111 VanDerWaalsContact OH-CE2 3.25Å; Y107-F111 WeakPolarHBondContact OH-CE2 3.17Å; Y107-V125 HydrophobicContact CD2-CG1 3.19Å; Y107-V125 HydrophobicContact CE2-CG1 3.45Å; Y107-V125 VanDerWaalsContact CE2-CG1 3.45Å; Y107-V125 HydrophobicContact CG-CG1 4.2Å; Y107-D129 VanDerWaalsContact CD1-CG 3.5Å; Y107-D129 WeakPolarHBondContact CD1-OD1 3.37Å; Y107-D129 WeakPolarHBondContact CD1-OD2 3.44Å; Y107-D129 VanDerWaalsContact CE1-OD2 3.23Å; Y107-D129 WeakPolarHBondContact CE1-OD2 3.28Å; Y107-D129 VanDerWaalsContact CG-OD2 3.23Å
108V87.1Confident89.3Confident19 Ų1937.9 Ų37.912%0.11518%0.178CC..  trans-1340.1-172.7-64.40000114.3Y53 A55 C101 Q106Y53-V108 WeakPolarHBondContact O-CB 3.32Å; Y53-V108 VanDerWaalsContact O-CG1 3.31Å; Y53-V108 WeakPolarHBondContact O-CG1 3.37Å; A55-V108 HydrophobicContact CB-CG2 4.16Å; C101-V108 WeakPolarHBondContact O-CG2 3.29Å; C101-V108 PolarHBondContact O-N 2.81Å; Q106-V108 HydrophobicContact CG-CG1 4.39Å
109C88.9Confident89Confident12 Ų1237.7 Ų37.78%0.08118%0.177CC..  trans-80.6150.5177.9-86.40000112.6L45 C101 Y107L45-C109 HydrophobicContact CD1-CB 3.56Å; C101-C109 WeakPolarHBondContact CA-SG 2.92Å; C101-C109 HydrophobicContact CB-CB 3.46Å; C101-C109 VanDerWaalsContact CB-CB 3.46Å; C101-C109 WeakPolarHBondContact CB-SG 3.2Å; C101-C109 WeakPolarHBondContact SG-CB 3.44Å; C101-C109 CovalentContact SG-SG 2.01Å; C101-C109 PolarHBondContact SG-SG 3.48Å; Y107-C109 HydrophobicContact CE1-CB 3.91Å; Y107-C109 WeakPolarHBondContact CE1-O 3.34Å; Y107-C109 HydrophobicContact CE2-CB 4.01Å; Y107-C109 WeakPolarHBondContact OH-CB 2.98Å
110R85.9Confident88.8Confident24 Ų2439.4 Ų39.49%0.09118%0.184CC..  trans-131.1129.4-174.8-175.2177.5-165.1145.7-0.5110.5L45 D46 D49 S50 V368 E372L45-R110 CarbonylContact C-O 3.1Å; L45-R110 WeakPolarHBondContact CA-O 3.26Å; L45-R110 WeakPolarHBondContact CD1-O 3.12Å; D46-R110 HydrophobicContact CB-CB 4.32Å; D46-R110 HydrophobicContact CB-CG 4.36Å; D46-R110 PolarHBondContact N-O 3.32Å; D49-R110 WeakPolarHBondContact OD2-CD 3.4Å; D49-R110 IonicContact OD2-CZ 2.64Å; D49-R110 IonicContact OD2-NE 3.31Å; D49-R110 IonicContact OD2-NH1 3.4Å; D49-R110 PolarHBondContact OD2-NH1 2.84Å; S50-R110 PolarHBondContact OG-N 3.26Å; R110-V368 VanDerWaalsContact NH2-CG1 3.35Å; R110-V368 PolarHBondContact NH2-O 3.33Å; R110-E372 IonicContact CZ-OE2 3.79Å; R110-E372 IonicContact NH1-OE1 2.77Å; R110-E372 IonicContact NH1-OE2 3.83Å; R110-E372 PolarHBondContact NH1-OE2 2.92Å; R110-E372 IonicContact NH2-OE2 3.55Å; R110-E372 PolarHBondContact NH2-OE2 2.81Å
111F87.3Confident88.5Confident11 Ų1138.8 Ų38.85%0.04818%0.18CC..EExtended strand (participates in β ladder)trans-109.1140.6176.8-68.8-81000111.9F43 V44 L45 V81 Y107 N119 I121 F429F43-F111 HydrophobicContact CB-CB 4.36Å; F43-F111 HydrophobicContact CD1-CB 4.16Å; V44-F111 WeakPolarHBondContact O-CA 3.4Å; L45-F111 HydrophobicContact CB-CD1 4.39Å; L45-F111 HydrophobicContact CB-CE1 4.15Å; L45-F111 HydrophobicContact CD1-CD1 4.37Å; L45-F111 HydrophobicContact CD1-CE1 4.03Å; L45-F111 HydrophobicContact CD1-CE2 4.47Å; L45-F111 HydrophobicContact CD1-CZ 4.1Å; V81-F111 HydrophobicContact CG1-CZ 3.88Å; Y107-F111 VanDerWaalsContact OH-CE2 3.25Å; Y107-F111 WeakPolarHBondContact OH-CE2 3.17Å; F111-N119 HydrophobicContact CE1-CB 3.78Å; F111-N119 HydrophobicContact CZ-CB 4.18Å; F111-I121 HydrophobicContact CE2-CD1 3.56Å; F111-I121 HydrophobicContact CE2-CG1 4.5Å; F111-I121 HydrophobicContact CZ-CD1 3.89Å; F111-I121 HydrophobicContact CZ-CG1 4.38Å; F111-F429 HydrophobicContact CB-CB 3.74Å; F111-F429 HydrophobicContact CB-CD1 3.79Å; F111-F429 HydrophobicContact CB-CD2 3.63Å; F111-F429 HydrophobicContact CB-CE1 4.3Å; F111-F429 HydrophobicContact CB-CE2 4.14Å; F111-F429 HydrophobicContact CB-CG 3.42Å; F111-F429 VanDerWaalsContact CB-CG 3.42Å; F111-F429 HydrophobicContact CB-CZ 4.44Å; F111-F429 HydrophobicContact CD1-CE2 4.36Å; F111-F429 HydrophobicContact CD1-CZ 4.38Å; F111-F429 AromaticContact CD2-CD1 3.34Å; F111-F429 HydrophobicContact CD2-CD1 3.34Å; F111-F429 HydrophobicContact CD2-CD2 4.3Å; F111-F429 AromaticContact CD2-CE1 3.2Å; F111-F429 HydrophobicContact CD2-CE1 3.2Å; F111-F429 HydrophobicContact CD2-CE2 4.17Å; F111-F429 AromaticContact CD2-CG 3.91Å; F111-F429 HydrophobicContact CD2-CG 3.91Å; F111-F429 AromaticContact CD2-CZ 3.64Å; F111-F429 HydrophobicContact CD2-CZ 3.64Å; F111-F429 HydrophobicContact CE2-CD1 4.13Å; F111-F429 AromaticContact CE2-CE1 3.52Å; F111-F429 HydrophobicContact CE2-CE1 3.52Å; F111-F429 AromaticContact CE2-CZ 3.81Å; F111-F429 HydrophobicContact CE2-CZ 3.81Å; F111-F429 AromaticContact CG-CD1 3.83Å; F111-F429 HydrophobicContact CG-CD1 3.83Å; F111-F429 AromaticContact CG-CD2 3.98Å; F111-F429 HydrophobicContact CG-CD2 3.98Å; F111-F429 AromaticContact CG-CE1 3.85Å; F111-F429 HydrophobicContact CG-CE1 3.85Å; F111-F429 AromaticContact CG-CE2 3.98Å; F111-F429 HydrophobicContact CG-CE2 3.98Å; F111-F429 AromaticContact CG-CG 3.9Å; F111-F429 HydrophobicContact CG-CG 3.9Å; F111-F429 AromaticContact CG-CZ 3.91Å; F111-F429 HydrophobicContact CG-CZ 3.91Å; F111-F429 HydrophobicContact CZ-CE1 4.42Å; F111-F429 HydrophobicContact CZ-CZ 4.29Å
112V87.5Confident88.2Confident5 Ų541.1 Ų41.13%0.0319%0.189CC..EExtended strand (participates in β ladder)trans-130.4139.3179.3-1760000109.2F43 V44 D46 K114 V363 V368F43-V112 WeakPolarHBondContact CA-O 3.41Å; F43-V112 VanDerWaalsContact CD1-C 3.47Å; V44-V112 PolarHBondContact N-O 3.23Å; V44-V112 PolarHBondContact O-N 3.17Å; D46-V112 HydrophobicContact CB-CG2 3.97Å; V112-K114 PolarHBondContact O-N 3.47Å; V112-K114 VanDerWaalsContact O-N 3.11Å; V112-V363 HydrophobicContact CB-CG1 3.67Å; V112-V363 HydrophobicContact CG1-CG1 3.56Å; V112-V363 HydrophobicContact CG2-CG1 3.68Å; V112-V368 HydrophobicContact CB-CG2 4.35Å; V112-V368 HydrophobicContact CG1-CG2 3.99Å; V112-V368 HydrophobicContact CG2-CB 4.42Å; V112-V368 HydrophobicContact CG2-CG2 3.48Å; V112-V368 VanDerWaalsContact CG2-CG2 3.48Å
113R87.5Confident87.3Confident95 Ų9540.8 Ų40.836%0.35819%0.188SC..EExtended strand (participates in β ladder)trans-63.1114.3-176.4-167.1-169.1-173177.34.5111.5D42 F43 K426 D427D42-R113 CarbonylContact O-C 3.56Å; D42-R113 VanDerWaalsContact O-CA 3.29Å; D42-R113 WeakPolarHBondContact O-CA 3.25Å; D42-R113 WeakPolarHBondContact O-CG 3.4Å; F43-R113 HydrophobicContact CD1-CB 4.17Å; F43-R113 HydrophobicContact CD2-CG 4.44Å; F43-R113 HydrophobicContact CE1-CB 3.74Å; F43-R113 HydrophobicContact CE1-CG 4.39Å; F43-R113 HydrophobicContact CE2-CB 4.21Å; F43-R113 HydrophobicContact CE2-CG 3.96Å; F43-R113 HydrophobicContact CZ-CB 3.76Å; F43-R113 HydrophobicContact CZ-CG 3.94Å; R113-K426 VanDerWaalsContact CD-O 3.28Å; R113-K426 WeakPolarHBondContact CD-O 3.18Å; R113-K426 PolarHBondContact NE-O 3.36Å; R113-K426 PolarHBondContact NH1-O 3.15Å; R113-D427 WeakPolarHBondContact CD-OD1 3.17Å; R113-D427 IonicContact CZ-OD1 3.95Å; R113-D427 IonicContact NE-OD1 3.88Å; R113-D427 IonicContact NH1-OD1 2.69Å; R113-D427 PolarHBondContact NH1-OD1 2.87Å
114K89.1Confident85.9Confident51 Ų5144.8 Ų44.822%0.22222%0.215CC..  trans-147.7124177.4-170.6-174.1-176.291.80110.3D42 V44 V112 F117 I361 P362D42-K114 CarbonylContact C-O 3.58Å; D42-K114 VanDerWaalsContact CA-O 3.24Å; D42-K114 WeakPolarHBondContact CA-O 3.45Å; D42-K114 CarbonylContact O-C 3.5Å; D42-K114 PolarHBondContact O-N 3.07Å; D42-K114 VanDerWaalsContact O-O 3.12Å; V44-K114 HydrophobicContact CB-CB 4.09Å; V44-K114 HydrophobicContact CB-CD 4.16Å; V44-K114 HydrophobicContact CG1-CB 3.63Å; V44-K114 HydrophobicContact CG1-CD 3.67Å; V44-K114 HydrophobicContact CG1-CG 4.3Å; V112-K114 PolarHBondContact O-N 3.47Å; V112-K114 VanDerWaalsContact O-N 3.11Å; K114-F117 HydrophobicContact CB-CD2 4.32Å; K114-F117 HydrophobicContact CD-CD2 3.89Å; K114-F117 HydrophobicContact CD-CE2 3.51Å; K114-F117 HydrophobicContact CD-CZ 4.27Å; K114-F117 HydrophobicContact CG-CD2 4.04Å; K114-F117 HydrophobicContact CG-CE2 4.04Å; K114-I361 HydrophobicContact CD-CG2 3.49Å; K114-I361 VanDerWaalsContact CD-CG2 3.49Å; K114-I361 VanDerWaalsContact CE-CG2 3.42Å; K114-P362 VanDerWaalsContact NZ-CD 3.35Å; K114-P362 PolarHBondContact NZ-O 3.23Å
115K89.8Confident84.5Confident163 Ų16342.9 Ų42.971%0.70921%0.207SC*.THydrogen-bonded Turntrans-63.3144.2-175.2-65.3-163.3170.4-171.90113.8D42 F117D42-K115 HydrophobicContact CB-CG 4.43Å; D42-K115 WeakPolarHBondContact OD1-CA 3.29Å; K115-F117 WeakPolarHBondContact O-CD2 3.44Å
116G89.8Confident83.2Confident27 Ų2738.7 Ų38.728%0.27819%0.187SC..THydrogen-bonded Turntrans83.817.5174.300000114.8D42 N86D42-G116 PolarHBondContact OD1-N 3.39Å; N86-G116 PolarHBondContact N-O 3.29Å
117F91.4Very high81.7Confident18 Ų1843.5 Ų43.58%0.07921%0.209CC..EExtended strand (participates in β ladder)trans-117.5145.3175.1-70.6-93.8000111.4D42 F43 V44 F83 M84 E85 K114 K115 I361D42-F117 PolarHBondContact N-O 2.7Å; F43-F117 VanDerWaalsContact O-CB 3.28Å; F43-F117 WeakPolarHBondContact O-CB 3.43Å; V44-F117 HydrophobicContact CB-CB 4.2Å; V44-F117 HydrophobicContact CB-CD1 4.08Å; V44-F117 HydrophobicContact CB-CD2 4.17Å; V44-F117 HydrophobicContact CB-CG 3.87Å; V44-F117 HydrophobicContact CG2-CD1 3.59Å; V44-F117 HydrophobicContact CG2-CD2 4.37Å; V44-F117 HydrophobicContact CG2-CE1 3.76Å; V44-F117 HydrophobicContact CG2-CG 3.92Å; V44-F117 HydrophobicContact CG2-CZ 4.25Å; F83-F117 HydrophobicContact CD2-CD1 4.43Å; M84-F117 WeakPolarHBondContact O-CA 3.1Å; E85-F117 HydrophobicContact CB-CD1 4.39Å; E85-F117 HydrophobicContact CB-CE1 4.05Å; E85-F117 HydrophobicContact CG-CE1 4.2Å; E85-F117 HydrophobicContact CG-CZ 4.18Å; K114-F117 HydrophobicContact CB-CD2 4.32Å; K114-F117 HydrophobicContact CD-CD2 3.89Å; K114-F117 HydrophobicContact CD-CE2 3.51Å; K114-F117 HydrophobicContact CD-CZ 4.27Å; K114-F117 HydrophobicContact CG-CD2 4.04Å; K114-F117 HydrophobicContact CG-CE2 4.04Å; K115-F117 WeakPolarHBondContact O-CD2 3.44Å; F117-I361 HydrophobicContact CE1-CD1 4.29Å; F117-I361 HydrophobicContact CZ-CD1 4.36Å
118L90.1Very high79.8Confident13 Ų1345.2 Ų45.27%0.06823%0.225CC..EExtended strand (participates in β ladder)trans-123.2154.7171.1-68.6178.5000109.4E41 F83 M84 N86E41-L118 HydrophobicContact CB-CD2 3.86Å; E41-L118 HydrophobicContact CG-CD2 3.52Å; F83-L118 CarbonylContact C-O 3.57Å; F83-L118 VanDerWaalsContact CA-O 3.29Å; F83-L118 WeakPolarHBondContact CA-O 3.33Å; F83-L118 WeakPolarHBondContact CB-O 3.43Å; M84-L118 PolarHBondContact N-O 2.92Å; M84-L118 PolarHBondContact O-N 2.8Å; N86-L118 WeakPolarHBondContact OD1-CD1 3.34Å; N86-L118 WeakPolarHBondContact OD1-CG 3.29Å
119N90.4Very high77.7Confident0 Ų047.5 Ų47.50%024%0.237CC..EExtended strand (participates in β ladder)trans-141.8143.8-179.546.577000109.2G39 R40 F43 F83 F111 F429G39-N119 VanDerWaalsContact C-OD1 3.27Å; G39-N119 WeakPolarHBondContact CA-OD1 3.43Å; G39-N119 PolarHBondContact N-O 3.18Å; R40-N119 PolarHBondContact N-OD1 3.03Å; R40-N119 PolarHBondContact O-ND2 2.94Å; F43-N119 PolarHBondContact O-ND2 2.93Å; F43-N119 VanDerWaalsContact O-ND2 3.11Å; F83-N119 HydrophobicContact CB-CB 4.08Å; F111-N119 HydrophobicContact CE1-CB 3.78Å; F111-N119 HydrophobicContact CZ-CB 4.18Å; N119-F429 VanDerWaalsContact OD1-CE2 3.3Å; N119-F429 WeakPolarHBondContact OD1-CE2 3.3Å; N119-F429 VanDerWaalsContact OD1-CZ 3.23Å; N119-F429 WeakPolarHBondContact OD1-CZ 3.37Å
120Y89.9Confident75.7Confident35 Ų3549.7 Ų49.714%0.13725%0.247CC..EExtended strand (participates in β ladder)trans-129.1131175.1-77.2-101.2000107.5F36 E37 K38 T66 I70 V81 A82 M84F36-Y120 HydrophobicContact CB-CD1 4.41Å; E37-Y120 WeakPolarHBondContact O-CA 3.49Å; K38-Y120 HydrophobicContact CB-CD1 4.1Å; K38-Y120 HydrophobicContact CB-CE1 3.6Å; K38-Y120 HydrophobicContact CG-CE1 4.02Å; K38-Y120 HydrophobicContact CG-CE2 4.13Å; T66-Y120 HydrophobicContact CG2-CD2 4.27Å; T66-Y120 HydrophobicContact CG2-CE2 3.43Å; T66-Y120 VanDerWaalsContact CG2-CE2 3.43Å; I70-Y120 HydrophobicContact CD1-CD1 3.48Å; I70-Y120 VanDerWaalsContact CD1-CD1 3.48Å; I70-Y120 HydrophobicContact CD1-CD2 4.17Å; I70-Y120 HydrophobicContact CD1-CE1 3.66Å; I70-Y120 HydrophobicContact CD1-CE2 4.35Å; I70-Y120 HydrophobicContact CD1-CG 3.74Å; I70-Y120 HydrophobicContact CG1-CD1 4.31Å; I70-Y120 HydrophobicContact CG1-CG 4.13Å; V81-Y120 WeakPolarHBondContact CA-O 3.22Å; A82-Y120 PolarHBondContact N-O 3.34Å; A82-Y120 PolarHBondContact O-N 3.37Å; M84-Y120 HydrophobicContact CE-CD2 3.47Å; M84-Y120 VanDerWaalsContact CE-CD2 3.47Å; M84-Y120 HydrophobicContact CE-CE2 4.03Å; M84-Y120 HydrophobicContact CE-CG 4.21Å
121I88.1Confident73.6Confident6 Ų651.3 Ų51.33%0.03127%0.266CS..EExtended strand (participates in β ladder)trans-127.4137.6-173.9-54.5-177.2000107.6F36 E37 N80 V81 F111 V125 F429 I431F36-I121 CarbonylContact C-O 3.42Å; F36-I121 WeakPolarHBondContact CA-O 3.24Å; E37-I121 PolarHBondContact N-O 3.38Å; E37-I121 PolarHBondContact O-N 2.7Å; N80-I121 WeakPolarHBondContact O-CA 3.25Å; V81-I121 HydrophobicContact CG2-CG1 4.12Å; V81-I121 HydrophobicContact CG2-CG2 4.16Å; F111-I121 HydrophobicContact CE2-CD1 3.56Å; F111-I121 HydrophobicContact CE2-CG1 4.5Å; F111-I121 HydrophobicContact CZ-CD1 3.89Å; F111-I121 HydrophobicContact CZ-CG1 4.38Å; I121-V125 HydrophobicContact CG2-CB 4.33Å; I121-V125 HydrophobicContact CG2-CG1 4.43Å; I121-F429 HydrophobicContact CD1-CE1 3.74Å; I121-F429 HydrophobicContact CD1-CZ 3.89Å; I121-I431 HydrophobicContact CD1-CD1 4.01Å
122R85.2Confident71.5Confident49 Ų4954.1 Ų54.119%0.18528%0.284CS..EExtended strand (participates in β ladder)trans-72.9135.2-179.3-167.2-169.9-74.4-82.57.8111S35 F36 C79 N80 V124 V125 Y126S35-R122 VanDerWaalsContact O-CA 3.3Å; S35-R122 WeakPolarHBondContact O-CA 3.38Å; S35-R122 VanDerWaalsContact O-CG 3.25Å; S35-R122 WeakPolarHBondContact O-CG 3.46Å; S35-R122 PolarHBondContact OG-NH1 2.53Å; F36-R122 HydrophobicContact CD1-CB 4.2Å; F36-R122 HydrophobicContact CE1-CB 3.86Å; F36-R122 HydrophobicContact CE2-CB 4.43Å; F36-R122 HydrophobicContact CE2-CG 4.33Å; F36-R122 HydrophobicContact CZ-CB 3.97Å; F36-R122 HydrophobicContact CZ-CG 4.29Å; C79-R122 PolarHBondContact O-NE 2.84Å; C79-R122 PolarHBondContact O-NH2 2.94Å; C79-R122 VanDerWaalsContact O-NH2 3.11Å; N80-R122 HydrophobicContact CB-CB 4.28Å; N80-R122 PolarHBondContact O-N 2.9Å; R122-V124 VanDerWaalsContact C-N 3.27Å; R122-V124 HydrophobicContact CG-CG2 4.01Å; R122-V124 PolarHBondContact O-N 2.98Å; R122-V124 VanDerWaalsContact O-N 3.13Å; R122-V125 WeakPolarHBondContact O-CB 3.44Å; R122-V125 PolarHBondContact O-N 2.92Å; R122-Y126 PolarHBondContact O-N 2.96Å
123D71.8Confident69.6Low52 Ų5259.5 Ų59.528%0.27831%0.307SS..Hα-helixtrans-57.9-34.9-169.9-42.4-17.3000113.8S35 F36 E37 V125 Y126 E127S35-D123 VanDerWaalsContact CA-OD2 3.3Å; S35-D123 WeakPolarHBondContact CA-OD2 3.23Å; S35-D123 PolarHBondContact O-N 3.36Å; S35-D123 VanDerWaalsContact O-N 3.17Å; S35-D123 VanDerWaalsContact O-OD1 3.1Å; F36-D123 PolarHBondContact N-OD1 3.24Å; E37-D123 PolarHBondContact N-OD1 3.33Å; E37-D123 VanDerWaalsContact N-OD1 3.15Å; D123-V125 PolarHBondContact O-N 2.83Å; D123-Y126 VanDerWaalsContact O-CB 3.25Å; D123-Y126 WeakPolarHBondContact O-CB 3.34Å; D123-Y126 PolarHBondContact O-N 3.26Å; D123-E127 PolarHBondContact O-N 2.83Å
124V62.9Low67.4Low115 Ų11560.3 Ų60.370%0.69732%0.318SS*.Hα-helixtrans-65.9-8.2176.5-59.30000114.3R122R122-V124 VanDerWaalsContact C-N 3.27Å; R122-V124 HydrophobicContact CG-CG2 4.01Å; R122-V124 PolarHBondContact O-N 2.98Å; R122-V124 VanDerWaalsContact O-N 3.13Å
125V58.9Low65.4Low1 Ų162.3 Ų62.31%0.00633%0.331CS..Hα-helixtrans-105.6-19.6174.3-176.60000111.2N80 L102 Y107 I121 R122 D123 S128N80-V125 HydrophobicContact CB-CG2 3.81Å; L102-V125 HydrophobicContact CD1-CG2 3.84Å; L102-V125 HydrophobicContact CD2-CG1 3.98Å; L102-V125 HydrophobicContact CD2-CG2 4.16Å; L102-V125 HydrophobicContact CG-CG1 4.48Å; L102-V125 HydrophobicContact CG-CG2 4.1Å; Y107-V125 HydrophobicContact CD2-CG1 3.19Å; Y107-V125 HydrophobicContact CE2-CG1 3.45Å; Y107-V125 VanDerWaalsContact CE2-CG1 3.45Å; Y107-V125 HydrophobicContact CG-CG1 4.2Å; I121-V125 HydrophobicContact CG2-CB 4.33Å; I121-V125 HydrophobicContact CG2-CG1 4.43Å; R122-V125 WeakPolarHBondContact O-CB 3.44Å; R122-V125 PolarHBondContact O-N 2.92Å; D123-V125 PolarHBondContact O-N 2.83Å; V125-S128 PolarHBondContact O-OG 3.43Å; V125-S128 VanDerWaalsContact O-OG 3.08Å
126Y56.3Low63.1Low22 Ų2260.5 Ų60.59%0.08634%0.336CS..Hα-helixtrans-71.4-38.5179.9176.6-88.1000112.4E37 R122 D123 S128 D129 L130 I431 N433E37-Y126 WeakPolarHBondContact OE2-CE2 3.34Å; E37-Y126 PolarHBondContact OE2-OH 3.48Å; R122-Y126 PolarHBondContact O-N 2.96Å; D123-Y126 VanDerWaalsContact O-CB 3.25Å; D123-Y126 WeakPolarHBondContact O-CB 3.34Å; D123-Y126 PolarHBondContact O-N 3.26Å; Y126-S128 PolarHBondContact O-N 2.98Å; Y126-D129 PolarHBondContact O-N 3.21Å; Y126-L130 HydrophobicContact CD1-CD1 4.13Å; Y126-L130 HydrophobicContact CD2-CD1 3.41Å; Y126-L130 VanDerWaalsContact CD2-CD1 3.41Å; Y126-L130 HydrophobicContact CE1-CD1 3.96Å; Y126-L130 HydrophobicContact CE2-CD1 3.22Å; Y126-L130 HydrophobicContact CG-CD1 3.88Å; Y126-I431 HydrophobicContact CD2-CD1 4.1Å; Y126-I431 HydrophobicContact CE2-CB 3.97Å; Y126-I431 HydrophobicContact CE2-CD1 4.14Å; Y126-I431 HydrophobicContact CE2-CG2 3.83Å; Y126-N433 PolarHBondContact OH-ND2 2.98Å
127E52.6Low61.3Low168 Ų16861.6 Ų61.679%0.78535%0.347SS*.THydrogen-bonded Turntrans-64-24.4-179-65.5-172.4152.100113.4D123D123-E127 PolarHBondContact O-N 2.83Å
128S46.1Very low59.7Low63 Ų6370.8 Ų70.844%0.44139%0.391SS..THydrogen-bonded Turntrans-84.8-10.6179.759.40000115.6V125 Y126V125-S128 PolarHBondContact O-OG 3.43Å; V125-S128 VanDerWaalsContact O-OG 3.08Å; Y126-S128 PolarHBondContact O-N 2.98Å
129D43.1Very low59.1Low68 Ų6875.4 Ų75.436%0.36442%0.419SS..THydrogen-bonded Turntrans-108.1-24.4-177.6-72.8-40.3000114.1Y107 Y126Y107-D129 VanDerWaalsContact CD1-CG 3.5Å; Y107-D129 WeakPolarHBondContact CD1-OD1 3.37Å; Y107-D129 WeakPolarHBondContact CD1-OD2 3.44Å; Y107-D129 VanDerWaalsContact CE1-OD2 3.23Å; Y107-D129 WeakPolarHBondContact CE1-OD2 3.28Å; Y107-D129 VanDerWaalsContact CG-OD2 3.23Å; Y126-D129 PolarHBondContact O-N 3.21Å
130L46.1Very low58.7Low58 Ų5877.3 Ų77.330%0.30443%0.429SS..  trans-107.125.4-162.4-76.1161.1000115.9Y126 T132 I431Y126-L130 HydrophobicContact CD1-CD1 4.13Å; Y126-L130 HydrophobicContact CD2-CD1 3.41Å; Y126-L130 VanDerWaalsContact CD2-CD1 3.41Å; Y126-L130 HydrophobicContact CE1-CD1 3.96Å; Y126-L130 HydrophobicContact CE2-CD1 3.22Å; Y126-L130 HydrophobicContact CG-CD1 3.88Å; L130-T132 VanDerWaalsContact C-N 3.35Å; L130-I431 HydrophobicContact CD1-CB 3.9Å; L130-I431 HydrophobicContact CD1-CG1 4.5Å
131A42.8Very low58.3Low57 Ų5777.8 Ų77.847%0.47143%0.434SS..  trans-83.91.8170.300000114.5K133 E144A131-K133 VanDerWaalsContact C-N 3.31Å; A131-K133 PolarHBondContact O-N 3.06Å; A131-E144 HydrophobicContact CB-CG 4.42Å
132T41.5Very low58.3Low71 Ų7181.4 Ų81.444%0.43646%0.458SS..  trans-79.678.1178.4-48.80000112.5L130L130-T132 VanDerWaalsContact C-N 3.35Å
133K47.3Very low58.6Low118 Ų11879.2 Ų79.251%0.51345%0.45SS..  trans-140.2126.8165.9-90.9-176.6178.7171.70106.7A131A131-K133 VanDerWaalsContact C-N 3.31Å; A131-K133 PolarHBondContact O-N 3.06Å
134N43.3Very low59.3Low112 Ų11279 Ų7960%0.59945%0.447SS*.  cis-142.3-169.55.5-65.2-80.7000110.4
135L45.8Very low60.6Low92 Ų9273.9 Ų73.948%0.48242%0.417SS..SBendtrans-52159.7146.7-85.4173.7000110.7G137 Y392L135-G137 PolarHBondContact O-N 3.33Å; L135-Y392 HydrophobicContact CD1-CD1 4.2Å; L135-Y392 HydrophobicContact CD1-CE1 3.38Å; L135-Y392 HydrophobicContact CD1-CE2 3.93Å; L135-Y392 WeakPolarHBondContact CD1-OH 3.23Å; L135-Y392 HydrophobicContact CD2-CE2 4.02Å; L135-Y392 HydrophobicContact CG-CE1 4.13Å; L135-Y392 HydrophobicContact CG-CE2 3.78Å; L135-Y392 VanDerWaalsContact CG-CZ 3.47Å; L135-Y392 VanDerWaalsContact CG-OH 3.3Å; L135-Y392 WeakPolarHBondContact CG-OH 3.13Å
136P42.9Very low62.1Low126 Ų12675.6 Ų75.682%0.81843%0.427SS*.SBendtrans-54.6101.1174.323.6-35.6000111.4
137G51.7Low63.6Low50 Ų5074.6 Ų74.652%0.51542%0.423SS..  trans-98.3167.2165.300000109.5L135 V139L135-G137 PolarHBondContact O-N 3.33Å; G137-V139 PolarHBondContact O-N 2.79Å
138E57.5Low65.4Low211 Ų21167.4 Ų67.499%0.98639%0.394SS*.SBendtrans-70.76.6-179.3-59.3-178.5139.100114.1
139V77.2Confident67.5Low109 Ų10965.3 Ų65.366%0.66138%0.379SS*.SBendtrans-123.4111.4-178.2-176.50000108.8G137 N141G137-V139 PolarHBondContact O-N 2.79Å; V139-N141 PolarHBondContact O-ND2 3.48Å
140D81.8Confident69.9Low40 Ų4063.6 Ų63.621%0.21437%0.369CS..  trans-61.2141.9173.3-168.511.1000111.7H170 S217 Q219D140-H170 IonicContact OD1-CE1 3.84Å; D140-H170 PolarHBondContact OD1-CE1 2.8Å; D140-H170 IonicContact OD1-CG 2.62Å; D140-H170 IonicContact OD1-ND1 3.94Å; D140-H170 PolarHBondContact OD1-ND1 2.94Å; D140-H170 IonicContact OD2-ND1 2.9Å; D140-S217 WeakPolarHBondContact OD2-CB 3.48Å; D140-S217 PolarHBondContact OD2-OG 2.68Å; D140-Q219 VanDerWaalsContact CG-NE2 3.26Å; D140-Q219 PolarHBondContact OD1-NE2 3.22Å; D140-Q219 PolarHBondContact OD2-NE2 3.4Å
141N82.6Confident72.2Confident46 Ų4662.7 Ų62.725%0.24636%0.362CS..  trans-117.9149.9-176.5-58.8-87.9000108.8V139 D169 Q219V139-N141 PolarHBondContact O-ND2 3.48Å; N141-D169 PolarHBondContact N-OD1 3.34Å; N141-D169 PolarHBondContact ND2-OD2 2.85Å; N141-Q219 PolarHBondContact O-NE2 3.06Å
142P86.6Confident74.7Confident81 Ų8161 Ų6153%0.52635%0.346SS..  trans-65.1148.1177.528-34.8000110.5Q219P142-Q219 HydrophobicContact CB-CB 4.15Å
143P91.3Very high77.2Confident4 Ų457.6 Ų57.63%0.02633%0.325CS..  trans-63.4157.9178.326.6-35000111.3K167 D168 V213 D215 D221P143-K167 CarbonylContact C-O 3.54Å; P143-K167 WeakPolarHBondContact CA-O 3.42Å; P143-D168 WeakPolarHBondContact CA-OD1 3.22Å; P143-D168 HydrophobicContact CB-CB 4.12Å; P143-V213 HydrophobicContact CB-CG1 3.94Å; P143-V213 HydrophobicContact CG-CG1 4.25Å; P143-D215 HydrophobicContact CG-CB 4.28Å; P143-D221 WeakPolarHBondContact O-CB 3.4Å
144E86.9Confident79.3Confident46 Ų4653.3 Ų53.322%0.21531%0.307CS..BIsolated β-bridgetrans-101.8109.3174.4-175.5-158.9133.400108.7A131 S166 K167A131-E144 HydrophobicContact CB-CG 4.42Å; E144-S166 CarbonylContact O-C 3.59Å; E144-S166 WeakPolarHBondContact O-CA 3.28Å; E144-S166 VanDerWaalsContact O-CB 3.23Å; E144-S166 WeakPolarHBondContact O-CB 3.34Å; E144-K167 HydrophobicContact CB-CB 4.36Å; E144-K167 PolarHBondContact N-O 2.94Å; E144-K167 PolarHBondContact O-N 2.88Å; E144-K167 IonicContact OE1-NZ 3.73Å; E144-K167 PolarHBondContact OE1-NZ 2.65Å; E144-K167 IonicContact OE2-NZ 2.9Å; E144-K167 PolarHBondContact OE2-NZ 2.66Å
145A90.9Very high81.5Confident9 Ų950.2 Ų50.27%0.07429%0.293CS..  trans-82.2119.6-178.900000111.5V213 D221 T223A145-V213 HydrophobicContact CB-CB 4.07Å; A145-V213 HydrophobicContact CB-CG2 3.63Å; A145-D221 HydrophobicContact CB-CB 4.12Å; A145-D221 VanDerWaalsContact CB-OD2 3.29Å; A145-D221 WeakPolarHBondContact CB-OD2 3.42Å; A145-D221 PolarHBondContact N-OD2 3.22Å; A145-T223 HydrophobicContact CB-CG2 3.86Å; A145-T223 VanDerWaalsContact O-CB 3.23Å; A145-T223 WeakPolarHBondContact O-CB 3.2Å; A145-T223 VanDerWaalsContact O-CG2 3.24Å; A145-T223 WeakPolarHBondContact O-CG2 3.46Å
146N89.5Confident82.7Confident37 Ų3754.1 Ų54.120%0.19831%0.308CS..  trans-128.5110.1177.3-179-7.5000110.7G148 G163 E165 S166N146-G148 WeakPolarHBondContact OD1-CA 3.01Å; N146-G148 PolarHBondContact OD1-N 3.31Å; N146-G163 WeakPolarHBondContact O-CA 3.11Å; N146-E165 HydrophobicContact CB-CB 4.47Å; N146-E165 WeakPolarHBondContact ND2-CB 3.34Å; N146-S166 PolarHBondContact N-OG 3.26Å; N146-S166 PolarHBondContact O-OG 3.08Å
147G89Confident84.3Confident1 Ų150.9 Ų50.91%0.0128%0.283CS..  trans-90.63.6179.100000114.7N162G147-N162 CarbonylContact C-O 3.42Å
148G89.1Confident86.1Confident17 Ų1752 Ų5218%0.17528%0.283CS..  trans76.8-179.1-172.200000114N146 I225N146-G148 WeakPolarHBondContact OD1-CA 3.01Å; N146-G148 PolarHBondContact OD1-N 3.31Å; G148-I225 VanDerWaalsContact O-CG2 3.25Å; G148-I225 WeakPolarHBondContact O-CG2 3.01Å
149P90.1Very high87.7Confident19 Ų1942.1 Ų42.112%0.12324%0.236CC..SBendtrans-73.5156.1-176.629.5-36.3000112.8K104 R151K104-P149 HydrophobicContact CB-CB 3.85Å; K104-P149 WeakPolarHBondContact O-CA 3.33Å; P149-R151 WeakPolarHBondContact O-CD 3.44Å; P149-R151 PolarHBondContact O-NE 2.67Å
150D94.1Very high88.5Confident31 Ų3139.5 Ų39.517%0.16622%0.221CC..  trans-50.9149.1171.4-77.2-8.9000112.3K104 Q105 T226K104-D150 HydrophobicContact CB-CB 3.92Å; K104-D150 WeakPolarHBondContact CD-O 3.37Å; K104-D150 HydrophobicContact CG-CB 4.41Å; K104-D150 PolarHBondContact O-N 3.13Å; Q105-D150 WeakPolarHBondContact CG-OD2 3.4Å; Q105-D150 VanDerWaalsContact NE2-CG 3.27Å; Q105-D150 PolarHBondContact NE2-OD1 2.8Å; Q105-D150 PolarHBondContact NE2-OD2 2.67Å; Q105-D150 VanDerWaalsContact NE2-OD2 3.07Å; D150-T226 CarbonylContact C-O 3.57Å; D150-T226 WeakPolarHBondContact CA-O 2.97Å; D150-T226 WeakPolarHBondContact CB-O 3.23Å; D150-T226 WeakPolarHBondContact OD1-CA 3.2Å; D150-T226 WeakPolarHBondContact OD1-CB 3.13Å; D150-T226 PolarHBondContact OD1-N 2.76Å
151R94.1Very high89Confident40 Ų4037.7 Ų37.715%0.15121%0.211CC..EExtended strand (participates in β ladder)trans-119.2139.1-175.5-54.1-60176.3115.77.7111.2P149 V153 L159 T226 V227 L228P149-R151 WeakPolarHBondContact O-CD 3.44Å; P149-R151 PolarHBondContact O-NE 2.67Å; R151-V153 HydrophobicContact CB-CG1 4.23Å; R151-L159 HydrophobicContact CB-CD1 4.43Å; R151-L159 HydrophobicContact CB-CD2 3.78Å; R151-L159 HydrophobicContact CG-CD1 4.18Å; R151-L159 HydrophobicContact CG-CD2 3.89Å; R151-T226 PolarHBondContact N-O 3.44Å; R151-V227 HydrophobicContact CB-CG1 4.38Å; R151-V227 HydrophobicContact CB-CG2 4.26Å; R151-V227 CarbonylContact O-C 3.46Å; R151-V227 WeakPolarHBondContact O-CA 3.35Å; R151-L228 PolarHBondContact O-N 2.9Å
152V94.9Very high89.5Confident21 Ų2136.8 Ų36.813%0.12721%0.206CC..EExtended strand (participates in β ladder)trans-114124.5169.1-177.80000105.8L228 L230 A288V152-L228 WeakPolarHBondContact CA-O 3.46Å; V152-L228 HydrophobicContact CG2-CB 4.5Å; V152-L228 HydrophobicContact CG2-CD2 4.49Å; V152-L230 HydrophobicContact CG1-CD1 3.7Å; V152-L230 HydrophobicContact CG1-CD2 3.7Å; V152-L230 HydrophobicContact CG1-CG 3.7Å; V152-A288 HydrophobicContact CB-CB 4.33Å; V152-A288 HydrophobicContact CG1-CB 4.1Å; V152-A288 WeakPolarHBondContact O-CA 3.17Å; V152-A288 PolarHBondContact O-N 3.27Å
153V94.8Very high89.7Confident0 Ų032.9 Ų32.90%018%0.181CC..EExtended strand (participates in β ladder)trans-139.5156.5-172.2-540000112.3R151 L159 V227 L228 V229 L230 N287R151-V153 HydrophobicContact CB-CG1 4.23Å; V153-L159 HydrophobicContact CG1-CD1 4.23Å; V153-L159 HydrophobicContact CG1-CD2 4.09Å; V153-V227 HydrophobicContact CG1-CG1 4.46Å; V153-V227 HydrophobicContact CG2-CG1 3.93Å; V153-L228 PolarHBondContact N-O 2.98Å; V153-V229 HydrophobicContact CG2-CB 4.24Å; V153-V229 HydrophobicContact CG2-CG1 4.31Å; V153-V229 HydrophobicContact CG2-CG2 3.78Å; V153-V229 WeakPolarHBondContact O-CA 2.95Å; V153-L230 PolarHBondContact O-N 3.19Å; V153-N287 CarbonylContact C-O 3.57Å; V153-N287 VanDerWaalsContact CA-O 3.25Å; V153-N287 WeakPolarHBondContact CA-O 3.41Å; V153-N287 HydrophobicContact CG1-CB 4.24Å
154Q92Very high89.6Confident27 Ų2734.7 Ų34.713%0.12619%0.19CC..  trans-76.5156.6166.8-73.7-59.3-4000112.2S235 N287 A288 V292Q154-S235 PolarHBondContact NE2-OG 2.94Å; Q154-S235 PolarHBondContact OE1-OG 3.16Å; Q154-N287 PolarHBondContact N-O 2.79Å; Q154-A288 WeakPolarHBondContact CG-O 3.42Å; Q154-A288 PolarHBondContact NE2-O 2.93Å; Q154-V292 HydrophobicContact CG-CG2 3.8Å; Q154-V292 VanDerWaalsContact NE2-CG2 3.34Å
155P88.3Confident89.6Confident47 Ų4734.3 Ų34.331%0.30519%0.189SC..THydrogen-bonded Turntrans-59.7149.3174.2-22.934.4000113E157 S204 V229 L230P155-E157 PolarHBondContact O-N 2.88Å; P155-E157 VanDerWaalsContact O-N 3.14Å; P155-S204 WeakPolarHBondContact CG-OG 3.45Å; P155-V229 HydrophobicContact CB-CG1 4.15Å; P155-V229 HydrophobicContact CG-CG1 4.06Å; P155-L230 WeakPolarHBondContact CG-O 3.17Å
156Q72.6Confident89.5Confident174 Ų17434.5 Ų34.581%0.81319%0.189SC*.THydrogen-bonded Turntrans66.4-3.3178.5-51.1-174.1-15.300116.6L202Q156-L202 PolarHBondContact N-O 3Å
157E76.1Confident89.3Confident59 Ų5937.7 Ų37.728%0.27620%0.201SC..  trans-69.6143171.4-162.8-178.8-178.700111.5P155 N287P155-E157 PolarHBondContact O-N 2.88Å; P155-E157 VanDerWaalsContact O-N 3.14Å; E157-N287 WeakPolarHBondContact OE2-CA 3.5Å
158S89.4Confident89.1Confident74 Ų7439.5 Ų39.552%0.51721%0.211SC..  trans-88.3114.9170.559.10000110.3V199S158-V199 CarbonylContact C-O 3.57Å; S158-V199 WeakPolarHBondContact CA-O 3.28Å
159L91.6Very high88.7Confident3 Ų341.5 Ų41.52%0.01622%0.217CC..EExtended strand (participates in β ladder)trans-98.6136.5-179.2171.868.5000110.4R151 V153 L161 I198 V199 V227R151-L159 HydrophobicContact CB-CD1 4.43Å; R151-L159 HydrophobicContact CB-CD2 3.78Å; R151-L159 HydrophobicContact CG-CD1 4.18Å; R151-L159 HydrophobicContact CG-CD2 3.89Å; V153-L159 HydrophobicContact CG1-CD1 4.23Å; V153-L159 HydrophobicContact CG1-CD2 4.09Å; L159-L161 HydrophobicContact CD2-CD2 3.69Å; L159-L161 HydrophobicContact CG-CD2 3.89Å; L159-I198 WeakPolarHBondContact O-CA 3.29Å; L159-V199 HydrophobicContact CB-CG2 3.83Å; L159-V199 HydrophobicContact CD2-CG2 4.19Å; L159-V199 HydrophobicContact CG-CG2 4.23Å; L159-V199 PolarHBondContact N-O 3.11Å; L159-V199 WeakPolarHBondContact O-CG2 3.45Å; L159-V199 PolarHBondContact O-N 2.75Å; L159-V227 HydrophobicContact CD2-CB 4.4Å; L159-V227 HydrophobicContact CD2-CG1 3.72Å; L159-V227 HydrophobicContact CD2-CG2 3.72Å
160T92.4Very high88.3Confident54 Ų5444.9 Ų44.933%0.33123%0.231SC..EExtended strand (participates in β ladder)trans-94.1126172.5-57.90000110.4Q196T160-Q196 HydrophobicContact CG2-CG 3.53Å
161L93.5Very high87.9Confident1 Ų149.7 Ų49.71%0.00526%0.257CS..EExtended strand (participates in β ladder)trans-106.3135.1173.5-53.3-179.2000109.2L159 W177 Q196 V197 V199 F209 I225L159-L161 HydrophobicContact CD2-CD2 3.69Å; L159-L161 HydrophobicContact CG-CD2 3.89Å; L161-W177 HydrophobicContact CB-CH2 4Å; L161-W177 HydrophobicContact CB-CZ2 3.97Å; L161-W177 HydrophobicContact CB-CZ3 4.33Å; L161-W177 HydrophobicContact CD1-CE3 4.09Å; L161-W177 HydrophobicContact CD1-CH2 4.48Å; L161-W177 HydrophobicContact CD1-CZ3 4.01Å; L161-Q196 WeakPolarHBondContact O-CA 3.13Å; L161-V197 HydrophobicContact CB-CG2 3.91Å; L161-V197 HydrophobicContact CD1-CG2 4.29Å; L161-V197 HydrophobicContact CG-CG2 4.45Å; L161-V197 PolarHBondContact N-O 2.85Å; L161-V197 PolarHBondContact O-N 2.93Å; L161-V199 HydrophobicContact CD1-CG1 3.63Å; L161-V199 HydrophobicContact CD1-CG2 4.11Å; L161-V199 HydrophobicContact CG-CG1 4.19Å; L161-V199 HydrophobicContact CG-CG2 4.12Å; L161-F209 HydrophobicContact CD1-CB 4.1Å; L161-F209 HydrophobicContact CD1-CD1 4.38Å; L161-F209 HydrophobicContact CD1-CD2 4.08Å; L161-F209 HydrophobicContact CD1-CG 3.93Å; L161-I225 HydrophobicContact CD1-CD1 3.93Å; L161-I225 HydrophobicContact CD2-CD1 3.53Å; L161-I225 HydrophobicContact CG-CD1 4.19Å
162N91.4Very high87.8Confident27 Ų2749.3 Ų49.314%0.14426%0.258CS..EExtended strand (participates in β ladder)trans-127.1135-178.5-57.2-46.3000110.5G147 N164 Q196G147-N162 CarbonylContact C-O 3.42Å; N162-N164 WeakPolarHBondContact CB-OD1 3.25Å; N162-Q196 WeakPolarHBondContact OD1-CG 3.27Å; N162-Q196 PolarHBondContact OD1-NE2 3.14Å
163G91.4Very high87.7Confident0 Ų051.2 Ų51.20%027%0.269CS..  trans-95.811.8168.500000113.8N146 E165 S166 Y175 D195N146-G163 WeakPolarHBondContact O-CA 3.11Å; G163-E165 PolarHBondContact O-N 3.43Å; G163-E165 VanDerWaalsContact O-N 3.14Å; G163-S166 VanDerWaalsContact O-CB 3.22Å; G163-S166 WeakPolarHBondContact O-CB 3.32Å; G163-S166 PolarHBondContact O-N 2.99Å; G163-S166 PolarHBondContact O-OG 2.89Å; G163-Y175 WeakPolarHBondContact O-CE1 3.18Å; G163-D195 PolarHBondContact N-O 3.47Å
164N88.7Confident87.8Confident41 Ų4154.6 Ų54.622%0.21929%0.29CS..THydrogen-bonded Turntrans-67.8-12.3-166.971.4-85.7000115.5N162 N378N162-N164 WeakPolarHBondContact CB-OD1 3.25Å; N164-N378 PolarHBondContact ND2-OD1 2.94Å; N164-N378 PolarHBondContact OD1-OD1 2.87Å
165E87Confident88Confident39 Ų3955.6 Ų55.618%0.18229%0.293CS..THydrogen-bonded Turntrans-96.55173.9-62.3-163.2134.200112.6N146 G163 N378N146-E165 HydrophobicContact CB-CB 4.47Å; N146-E165 WeakPolarHBondContact ND2-CB 3.34Å; G163-E165 PolarHBondContact O-N 3.43Å; G163-E165 VanDerWaalsContact O-N 3.14Å; E165-N378 WeakPolarHBondContact CG-OD1 3.25Å; E165-N378 PolarHBondContact OE1-OD1 2.93Å
166S89.3Confident88.4Confident12 Ų1258 Ų588%0.08430%0.303CS..  trans-64.5144.3168.1-52.40000109.9E144 N146 G163E144-S166 CarbonylContact O-C 3.59Å; E144-S166 WeakPolarHBondContact O-CA 3.28Å; E144-S166 VanDerWaalsContact O-CB 3.23Å; E144-S166 WeakPolarHBondContact O-CB 3.34Å; N146-S166 PolarHBondContact N-OG 3.26Å; N146-S166 PolarHBondContact O-OG 3.08Å; G163-S166 VanDerWaalsContact O-CB 3.22Å; G163-S166 WeakPolarHBondContact O-CB 3.32Å; G163-S166 PolarHBondContact O-N 2.99Å; G163-S166 PolarHBondContact O-OG 2.89Å
167K85.1Confident89.5Confident105 Ų10550.6 Ų50.646%0.45727%0.267SS..BIsolated β-bridgetrans-127.4162.2-174.6-49.2-168.2-14585.70111P143 E144P143-K167 CarbonylContact C-O 3.54Å; P143-K167 WeakPolarHBondContact CA-O 3.42Å; E144-K167 HydrophobicContact CB-CB 4.36Å; E144-K167 PolarHBondContact N-O 2.94Å; E144-K167 PolarHBondContact O-N 2.88Å; E144-K167 IonicContact OE1-NZ 3.73Å; E144-K167 PolarHBondContact OE1-NZ 2.65Å; E144-K167 IonicContact OE2-NZ 2.9Å; E144-K167 PolarHBondContact OE2-NZ 2.66Å
168D84.9Confident90.4Very high38 Ų3851.2 Ų51.220%0.20327%0.27CS..  trans-162.8155.7-179.6-167.735.6000107.7P143 H170 I172 D215P143-D168 WeakPolarHBondContact CA-OD1 3.22Å; P143-D168 HydrophobicContact CB-CB 4.12Å; D168-H170 VanDerWaalsContact C-N 3.33Å; D168-H170 WeakPolarHBondContact CB-O 3.23Å; D168-H170 WeakPolarHBondContact OD2-CA 3.18Å; D168-H170 PolarHBondContact OD2-N 2.79Å; D168-H170 VanDerWaalsContact OD2-O 3.11Å; D168-I172 HydrophobicContact CB-CD1 4Å; D168-I172 HydrophobicContact CB-CG1 3.54Å; D168-D215 VanDerWaalsContact OD2-CB 3.23Å; D168-D215 WeakPolarHBondContact OD2-CB 3.23Å
169D81.1Confident90.7Very high59 Ų5949.9 Ų49.932%0.31626%0.257SS..SBendtrans-83.2-15168.259.1-31.9000112.6N141N141-D169 PolarHBondContact N-OD1 3.34Å; N141-D169 PolarHBondContact ND2-OD2 2.85Å
170H81.2Confident91Very high90 Ų9053 Ų5342%0.41728%0.276SS..SBendtrans-111.6-167.2169.8-7093.4000112.8D140 D168D140-H170 IonicContact OD1-CE1 3.84Å; D140-H170 PolarHBondContact OD1-CE1 2.8Å; D140-H170 IonicContact OD1-CG 2.62Å; D140-H170 IonicContact OD1-ND1 3.94Å; D140-H170 PolarHBondContact OD1-ND1 2.94Å; D140-H170 IonicContact OD2-ND1 2.9Å; D168-H170 VanDerWaalsContact C-N 3.33Å; D168-H170 WeakPolarHBondContact CB-O 3.23Å; D168-H170 WeakPolarHBondContact OD2-CA 3.18Å; D168-H170 PolarHBondContact OD2-N 2.79Å; D168-H170 VanDerWaalsContact OD2-O 3.11Å
171D86.8Confident91.2Very high132 Ų13253 Ų5371%0.70628%0.278SS*.  trans-85.5117.2177.5-84.3-34.8000110.9V173 S216D171-V173 PolarHBondContact O-N 2.77Å; D171-S216 PolarHBondContact O-N 3.03Å; D171-S216 VanDerWaalsContact O-N 3.08Å
172I91.3Very high91.1Very high33 Ų3354.8 Ų54.817%0.16930%0.297CS..  trans-64119.1169-62.3169.2000110.4D168 Y175 V213D168-I172 HydrophobicContact CB-CD1 4Å; D168-I172 HydrophobicContact CB-CG1 3.54Å; I172-Y175 HydrophobicContact CB-CE2 4.37Å; I172-Y175 HydrophobicContact CG2-CD2 4.15Å; I172-Y175 HydrophobicContact CG2-CE1 4.06Å; I172-Y175 HydrophobicContact CG2-CE2 3.49Å; I172-Y175 VanDerWaalsContact CG2-CE2 3.49Å; I172-Y175 VanDerWaalsContact CG2-CZ 3.44Å; I172-V213 HydrophobicContact CB-CG1 4.34Å; I172-V213 HydrophobicContact CD1-CG1 3.85Å; I172-V213 HydrophobicContact CG1-CG1 3.96Å; I172-V213 HydrophobicContact CG2-CG1 3.43Å; I172-V213 VanDerWaalsContact CG2-CG1 3.43Å
173V93.7Very high91.1Very high61 Ų6156.7 Ų56.737%0.3731%0.307SS..  trans-95.2-34.2-175.9-60.80000113.9D171 T214 D215D171-V173 PolarHBondContact O-N 2.77Å; V173-T214 WeakPolarHBondContact CG2-O 3.44Å; V173-T214 PolarHBondContact N-O 3.05Å; V173-D215 WeakPolarHBondContact CG2-O 3.3Å
174T95Very high91Very high71 Ų7162.9 Ų62.944%0.43635%0.345SS..EExtended strand (participates in β ladder)trans-137.8142.5-177.355.20000114.2T214T174-T214 PolarHBondContact N-O 2.77Å; T174-T214 PolarHBondContact O-N 2.67Å; T174-T214 WeakPolarHBondContact OG1-CB 3.15Å; T174-T214 PolarHBondContact OG1-OG1 3.43Å
175Y96.5Very high90.9Very high47 Ų4763.6 Ų63.618%0.18435%0.353CS..EExtended strand (participates in β ladder)trans-120.9128.6168.9-59.4-101.8000107.7G163 I172 K194 D195 L211 V213G163-Y175 WeakPolarHBondContact O-CE1 3.18Å; I172-Y175 HydrophobicContact CB-CE2 4.37Å; I172-Y175 HydrophobicContact CG2-CD2 4.15Å; I172-Y175 HydrophobicContact CG2-CE1 4.06Å; I172-Y175 HydrophobicContact CG2-CE2 3.49Å; I172-Y175 VanDerWaalsContact CG2-CE2 3.49Å; I172-Y175 VanDerWaalsContact CG2-CZ 3.44Å; Y175-K194 HydrophobicContact CD2-CB 4.27Å; Y175-D195 HydrophobicContact CD1-CB 4Å; Y175-D195 HydrophobicContact CD2-CB 4.02Å; Y175-D195 HydrophobicContact CE1-CB 3.94Å; Y175-D195 HydrophobicContact CE2-CB 3.97Å; Y175-D195 HydrophobicContact CG-CB 4.05Å; Y175-L211 HydrophobicContact CD1-CD1 4.12Å; Y175-V213 HydrophobicContact CD1-CG2 4.07Å; Y175-V213 HydrophobicContact CE1-CG2 4.32Å
176L96.4Very high91.2Very high98 Ų9862.5 Ų62.551%0.51335%0.351SS..EExtended strand (participates in β ladder)trans-127.3109.3-179.7178.664.3000110.2T212L176-T212 PolarHBondContact N-O 2.84Å; L176-T212 PolarHBondContact O-N 2.03Å
177W96.8Very high91.4Very high19 Ų1964.9 Ų64.97%0.07236%0.364CS..EExtended strand (participates in β ladder)trans-93.7134.2172.9-72.596.3000111L161 D195 V197 F209 Q210 L211 I225L161-W177 HydrophobicContact CB-CH2 4Å; L161-W177 HydrophobicContact CB-CZ2 3.97Å; L161-W177 HydrophobicContact CB-CZ3 4.33Å; L161-W177 HydrophobicContact CD1-CE3 4.09Å; L161-W177 HydrophobicContact CD1-CH2 4.48Å; L161-W177 HydrophobicContact CD1-CZ3 4.01Å; W177-D195 PolarHBondContact NE1-O 3.46Å; W177-V197 HydrophobicContact CB-CG1 4.1Å; W177-V197 HydrophobicContact CB-CG2 3.88Å; W177-V197 HydrophobicContact CD2-CG2 4.01Å; W177-V197 HydrophobicContact CG-CB 4.5Å; W177-V197 HydrophobicContact CG-CG1 4.08Å; W177-V197 HydrophobicContact CG-CG2 3.58Å; W177-F209 HydrophobicContact CE3-CB 4.12Å; W177-F209 HydrophobicContact CZ3-CB 4.16Å; W177-Q210 WeakPolarHBondContact CA-O 3.06Å; W177-L211 HydrophobicContact CD2-CB 4.01Å; W177-L211 HydrophobicContact CD2-CD1 4.24Å; W177-L211 HydrophobicContact CE3-CB 3.9Å; W177-L211 HydrophobicContact CG-CD1 4.42Å; W177-L211 HydrophobicContact CH2-CB 3.84Å; W177-L211 HydrophobicContact CH2-CD2 4.38Å; W177-L211 HydrophobicContact CZ2-CB 3.92Å; W177-L211 HydrophobicContact CZ2-CD1 4.32Å; W177-L211 HydrophobicContact CZ2-CD2 3.94Å; W177-L211 HydrophobicContact CZ2-CG 4.27Å; W177-L211 HydrophobicContact CZ3-CB 3.82Å; W177-I225 HydrophobicContact CH2-CD1 3.86Å; W177-I225 HydrophobicContact CH2-CG1 4.47Å; W177-I225 HydrophobicContact CZ3-CD1 3.75Å; W177-I225 HydrophobicContact CZ3-CG1 4.04Å
178H95.1Very high91.9Very high71 Ų7162.7 Ų62.733%0.32936%0.357SS..EExtended strand (participates in β ladder)trans-144.2157.1170.369.9-80000112.7F209 Q210H178-F209 WeakPolarHBondContact O-CA 3.32Å; H178-Q210 PolarHBondContact N-O 2.87Å; H178-Q210 PolarHBondContact ND1-O 3.38Å; H178-Q210 PolarHBondContact O-N 3.48Å
179L96.4Very high92.4Very high47 Ų4766 Ų6625%0.24637%0.371CS..EExtended strand (participates in β ladder)trans-83.3122.4174.9-178.770.8000109.6S181 A186 I188 Y207 F209L179-S181 WeakPolarHBondContact CD1-O 3.3Å; L179-A186 HydrophobicContact CD2-CB 4.45Å; L179-I188 HydrophobicContact CB-CD1 4.45Å; L179-Y207 HydrophobicContact CD1-CD1 3.98Å; L179-F209 HydrophobicContact CB-CD1 4.37Å; L179-F209 HydrophobicContact CB-CE1 4.27Å; L179-F209 HydrophobicContact CD1-CD1 4.06Å; L179-F209 HydrophobicContact CD1-CE1 3.7Å; L179-F209 HydrophobicContact CD1-CE2 4.48Å; L179-F209 HydrophobicContact CD1-CZ 3.93Å
180V96.4Very high93Very high68 Ų6871.8 Ų71.841%0.41239%0.394SS..EExtended strand (participates in β ladder)trans-90.8-44.2176.5179.20000111.1K208 Q210V180-K208 HydrophobicContact CB-CB 4.3Å; V180-K208 PolarHBondContact N-O 3.31Å; V180-Q210 HydrophobicContact CG2-CB 3.44Å; V180-Q210 VanDerWaalsContact CG2-CB 3.44Å; V180-Q210 HydrophobicContact CG2-CG 4.46Å
181S96.3Very high93.6Very high54 Ų5469.1 Ų69.138%0.37838%0.384SS..EExtended strand (participates in β ladder)trans-150.1142.4178.265.60000110.9L179 Y207 K208L179-S181 WeakPolarHBondContact CD1-O 3.3Å; S181-Y207 CarbonylContact O-C 3.56Å; S181-Y207 VanDerWaalsContact O-CA 3.28Å; S181-Y207 WeakPolarHBondContact O-CA 3.46Å; S181-K208 PolarHBondContact N-O 3.38Å; S181-K208 PolarHBondContact O-N 3.41Å; S181-K208 WeakPolarHBondContact OG-CB 3.46Å; S181-K208 WeakPolarHBondContact OG-CG 3.15Å
182G92.8Very high93.9Very high38 Ų3869.3 Ų69.339%0.39239%0.39SS..SBendtrans148-171.6-179.500000110.6T184G182-T184 PolarHBondContact O-N 3.43Å
183N90.6Very high94Very high68 Ų6872.1 Ų72.136%0.36440%0.401SS..  trans-71.7124.6171.3-173.2-19.5000109.7S185 A186 Y207N183-S185 PolarHBondContact O-N 3.5Å; N183-S185 VanDerWaalsContact OD1-CB 3.27Å; N183-S185 WeakPolarHBondContact OD1-CB 3.33Å; N183-S185 PolarHBondContact OD1-N 2.69Å; N183-S185 PolarHBondContact OD1-OG 3.25Å; N183-A186 WeakPolarHBondContact O-CB 3.17Å; N183-A186 PolarHBondContact O-N 3.4Å; N183-A186 VanDerWaalsContact O-N 3.14Å; N183-Y207 HydrophobicContact CB-CE1 3.85Å; N183-Y207 WeakPolarHBondContact CB-OH 3.22Å; N183-Y207 VanDerWaalsContact N-CE1 3.31Å
184T89.5Confident93.9Very high130 Ų13076.7 Ų76.780%0.79842%0.416SS*.THydrogen-bonded Turntrans-66.8-4.9178.852.90000114.1G182 A186G182-T184 PolarHBondContact O-N 3.43Å; T184-A186 PolarHBondContact O-N 3.12Å
185S87.7Confident93.8Very high56 Ų5674.2 Ų74.239%0.39240%0.4SS..THydrogen-bonded Turntrans-71.5-15.4170.5-48.90000113.4N183 V187 N201N183-S185 PolarHBondContact O-N 3.5Å; N183-S185 VanDerWaalsContact OD1-CB 3.27Å; N183-S185 WeakPolarHBondContact OD1-CB 3.33Å; N183-S185 PolarHBondContact OD1-N 2.69Å; N183-S185 PolarHBondContact OD1-OG 3.25Å; S185-V187 PolarHBondContact O-N 3.21Å; S185-N201 PolarHBondContact O-ND2 2.83Å
186A92.2Very high93.6Very high16 Ų1673.4 Ų73.413%0.13240%0.398CS..  trans-61.9131.1177.300000111.2L179 N183 T184 S200 L202 Y207L179-A186 HydrophobicContact CD2-CB 4.45Å; N183-A186 WeakPolarHBondContact O-CB 3.17Å; N183-A186 PolarHBondContact O-N 3.4Å; N183-A186 VanDerWaalsContact O-N 3.14Å; T184-A186 PolarHBondContact O-N 3.12Å; A186-S200 WeakPolarHBondContact CA-O 3.42Å; A186-L202 HydrophobicContact CB-CD2 3.59Å; A186-Y207 HydrophobicContact CB-CD1 4.23Å; A186-Y207 HydrophobicContact CB-CE1 3.98Å
187V93.6Very high93.6Very high61 Ų6169.1 Ų69.137%0.3738%0.376SS..EExtended strand (participates in β ladder)trans-102.1135.9178.9-174.80000108.9S185 E189 V199 S200 N201S185-V187 PolarHBondContact O-N 3.21Å; V187-E189 HydrophobicContact CG1-CG 3.89Å; V187-V199 VanDerWaalsContact O-CA 3.29Å; V187-V199 WeakPolarHBondContact O-CA 3.4Å; V187-S200 PolarHBondContact N-O 2.67Å; V187-S200 PolarHBondContact O-N 2.81Å; V187-N201 HydrophobicContact CG2-CB 4.26Å
188I95.1Very high93.6Very high59 Ų5970.8 Ų70.830%0.30339%0.386SS..EExtended strand (participates in β ladder)trans-114.5111.2174.1-50.5-177.8000108.1L179 V197 V199 F209L179-I188 HydrophobicContact CB-CD1 4.45Å; I188-V197 HydrophobicContact CG2-CB 3.78Å; I188-V197 HydrophobicContact CG2-CG1 3.99Å; I188-V197 HydrophobicContact CG2-CG2 3.94Å; I188-V199 HydrophobicContact CG1-CG1 4.13Å; I188-V199 HydrophobicContact CG2-CG1 4.31Å; I188-F209 HydrophobicContact CD1-CD1 3.99Å; I188-F209 HydrophobicContact CD1-CE1 3.91Å; I188-F209 HydrophobicContact CG1-CE1 4.15Å
189E95.8Very high93.6Very high107 Ų10767.4 Ų67.450%0.537%0.37SS..EExtended strand (participates in β ladder)trans-104.3133.8179.2-60.2-170.2171.200110.6V187 V197 I198V187-E189 HydrophobicContact CG1-CG 3.89Å; E189-V197 CarbonylContact O-C 3.53Å; E189-V197 VanDerWaalsContact O-CA 3.27Å; E189-V197 WeakPolarHBondContact O-CA 3.46Å; E189-V197 WeakPolarHBondContact O-CB 2.91Å; E189-I198 PolarHBondContact N-O 3.4Å; E189-I198 PolarHBondContact O-N 2.91Å
190K94.5Very high93.5Very high182 Ų18266.5 Ų66.579%0.79137%0.367SS*.EExtended strand (participates in β ladder)trans-78.2137.1174.5-67.1-171177.4-170.70110.1
191T93.8Very high93.2Very high34 Ų3467.8 Ų67.821%0.20937%0.372CS..  trans-90.6-174.5175.170.50000111.9F193 Q196 I198T191-F193 PolarHBondContact O-N 3.41Å; T191-F193 PolarHBondContact OG1-N 2.8Å; T191-F193 VanDerWaalsContact OG1-N 3.14Å; T191-F193 PolarHBondContact OG1-O 3.04Å; T191-F193 VanDerWaalsContact OG1-O 3.11Å; T191-Q196 HydrophobicContact CG2-CB 4.46Å; T191-Q196 HydrophobicContact CG2-CG 3.72Å; T191-Q196 PolarHBondContact N-O 3.08Å; T191-Q196 WeakPolarHBondContact OG1-CB 2.94Å; T191-Q196 PolarHBondContact OG1-O 3.2Å; T191-Q196 PolarHBondContact OG1-OE1 3.11Å; T191-I198 HydrophobicContact CG2-CD1 3.91Å; T191-I198 HydrophobicContact CG2-CG1 3.76Å
192T93.3Very high93.1Very high135 Ų13565.3 Ų65.383%0.82836%0.355SS*.SBendtrans-65.9-18.6169.1500000113.4
193F92.4Very high93.1Very high92 Ų9265.6 Ų65.640%0.40435%0.353SS..SBendtrans-101.3133.3179.7-57-77.5000110.1T191 D195 Q196T191-F193 PolarHBondContact O-N 3.41Å; T191-F193 PolarHBondContact OG1-N 2.8Å; T191-F193 VanDerWaalsContact OG1-N 3.14Å; T191-F193 PolarHBondContact OG1-O 3.04Å; T191-F193 VanDerWaalsContact OG1-O 3.11Å; F193-D195 VanDerWaalsContact C-N 3.25Å; F193-D195 WeakPolarHBondContact CB-OD1 3.17Å; F193-D195 PolarHBondContact O-N 2.62Å; F193-Q196 HydrophobicContact CB-CB 4.13Å; F193-Q196 PolarHBondContact O-N 3.01Å
194K92.2Very high93.2Very high157 Ų15765 Ų6568%0.68335%0.354SS*.THydrogen-bonded Turntrans-61.3-35.9-175.1-68.2-177.2177.3-1770112.9Y175 Q196Y175-K194 HydrophobicContact CD2-CB 4.27Å; K194-Q196 VanDerWaalsContact C-N 3.32Å
195D91.8Very high93.4Very high19 Ų1960 Ų6010%0.10233%0.329CS..THydrogen-bonded Turntrans-80.5-7.7-175.358.1-73.1000114G163 Y175 W177 F193 R380G163-D195 PolarHBondContact N-O 3.47Å; Y175-D195 HydrophobicContact CD1-CB 4Å; Y175-D195 HydrophobicContact CD2-CB 4.02Å; Y175-D195 HydrophobicContact CE1-CB 3.94Å; Y175-D195 HydrophobicContact CE2-CB 3.97Å; Y175-D195 HydrophobicContact CG-CB 4.05Å; W177-D195 PolarHBondContact NE1-O 3.46Å; F193-D195 VanDerWaalsContact C-N 3.25Å; F193-D195 WeakPolarHBondContact CB-OD1 3.17Å; F193-D195 PolarHBondContact O-N 2.62Å; D195-R380 IonicContact OD1-CZ 3.62Å; D195-R380 IonicContact OD1-NH1 2.67Å; D195-R380 PolarHBondContact OD1-NH1 2.67Å; D195-R380 VanDerWaalsContact OD1-NH1 3.08Å; D195-R380 IonicContact OD1-NH2 3.88Å; D195-R380 IonicContact OD2-CZ 2.65Å; D195-R380 VanDerWaalsContact OD2-CZ 3.25Å; D195-R380 IonicContact OD2-NH1 3.17Å; D195-R380 PolarHBondContact OD2-NH1 2.98Å; D195-R380 IonicContact OD2-NH2 2.67Å; D195-R380 PolarHBondContact OD2-NH2 2.97Å
196Q93.9Very high93.7Very high31 Ų3161.2 Ų61.215%0.14533%0.334CS..EExtended strand (participates in β ladder)trans-123.9134.5-168.9173.2-176.889.700113.3T160 L161 N162 T191 F193 K194T160-Q196 HydrophobicContact CG2-CG 3.53Å; L161-Q196 WeakPolarHBondContact O-CA 3.13Å; N162-Q196 WeakPolarHBondContact OD1-CG 3.27Å; N162-Q196 PolarHBondContact OD1-NE2 3.14Å; T191-Q196 HydrophobicContact CG2-CB 4.46Å; T191-Q196 HydrophobicContact CG2-CG 3.72Å; T191-Q196 PolarHBondContact N-O 3.08Å; T191-Q196 WeakPolarHBondContact OG1-CB 2.94Å; T191-Q196 PolarHBondContact OG1-O 3.2Å; T191-Q196 PolarHBondContact OG1-OE1 3.11Å; F193-Q196 HydrophobicContact CB-CB 4.13Å; F193-Q196 PolarHBondContact O-N 3.01Å; K194-Q196 VanDerWaalsContact C-N 3.32Å
197V95.8Very high93.9Very high8 Ų860.6 Ų60.65%0.04833%0.328CS..EExtended strand (participates in β ladder)trans-126.5151.5171.8-630000111L161 W177 I188 E189 V199L161-V197 HydrophobicContact CB-CG2 3.91Å; L161-V197 HydrophobicContact CD1-CG2 4.29Å; L161-V197 HydrophobicContact CG-CG2 4.45Å; L161-V197 PolarHBondContact N-O 2.85Å; L161-V197 PolarHBondContact O-N 2.93Å; W177-V197 HydrophobicContact CB-CG1 4.1Å; W177-V197 HydrophobicContact CB-CG2 3.88Å; W177-V197 HydrophobicContact CD2-CG2 4.01Å; W177-V197 HydrophobicContact CG-CB 4.5Å; W177-V197 HydrophobicContact CG-CG1 4.08Å; W177-V197 HydrophobicContact CG-CG2 3.58Å; I188-V197 HydrophobicContact CG2-CB 3.78Å; I188-V197 HydrophobicContact CG2-CG1 3.99Å; I188-V197 HydrophobicContact CG2-CG2 3.94Å; E189-V197 CarbonylContact O-C 3.53Å; E189-V197 VanDerWaalsContact O-CA 3.27Å; E189-V197 WeakPolarHBondContact O-CA 3.46Å; E189-V197 WeakPolarHBondContact O-CB 2.91Å; V197-V199 HydrophobicContact CG2-CG1 4.36Å
198I95.6Very high94.1Very high54 Ų5461.6 Ų61.628%0.27733%0.327SS..EExtended strand (participates in β ladder)trans-102.2126.7168.1-64.5167.7000107.1L159 E189 T191L159-I198 WeakPolarHBondContact O-CA 3.29Å; E189-I198 PolarHBondContact N-O 3.4Å; E189-I198 PolarHBondContact O-N 2.91Å; T191-I198 HydrophobicContact CG2-CD1 3.91Å; T191-I198 HydrophobicContact CG2-CG1 3.76Å
199V95.3Very high94.2Very high0 Ų058.8 Ų58.80%031%0.313CS..EExtended strand (participates in β ladder)trans-105.2132.4172.9-58.70000109.8S158 L159 L161 V187 I188 V197 L202 F209S158-V199 CarbonylContact C-O 3.57Å; S158-V199 WeakPolarHBondContact CA-O 3.28Å; L159-V199 HydrophobicContact CB-CG2 3.83Å; L159-V199 HydrophobicContact CD2-CG2 4.19Å; L159-V199 HydrophobicContact CG-CG2 4.23Å; L159-V199 PolarHBondContact N-O 3.11Å; L159-V199 WeakPolarHBondContact O-CG2 3.45Å; L159-V199 PolarHBondContact O-N 2.75Å; L161-V199 HydrophobicContact CD1-CG1 3.63Å; L161-V199 HydrophobicContact CD1-CG2 4.11Å; L161-V199 HydrophobicContact CG-CG1 4.19Å; L161-V199 HydrophobicContact CG-CG2 4.12Å; V187-V199 VanDerWaalsContact O-CA 3.29Å; V187-V199 WeakPolarHBondContact O-CA 3.4Å; I188-V199 HydrophobicContact CG1-CG1 4.13Å; I188-V199 HydrophobicContact CG2-CG1 4.31Å; V197-V199 HydrophobicContact CG2-CG1 4.36Å; V199-L202 HydrophobicContact CG2-CD1 4.11Å; V199-F209 HydrophobicContact CB-CE1 4.35Å; V199-F209 HydrophobicContact CB-CZ 4.05Å; V199-F209 HydrophobicContact CG1-CD1 4.28Å; V199-F209 HydrophobicContact CG1-CE1 3.79Å; V199-F209 HydrophobicContact CG1-CZ 3.96Å; V199-F209 HydrophobicContact CG2-CE2 4.38Å; V199-F209 HydrophobicContact CG2-CZ 4.24Å
200S94.3Very high94.2Very high27 Ų2754.7 Ų54.719%0.18929%0.294CS..EExtended strand (participates in β ladder)trans-144.3177.8-173.3730000111.9A186 V187 L202A186-S200 WeakPolarHBondContact CA-O 3.42Å; V187-S200 PolarHBondContact N-O 2.67Å; V187-S200 PolarHBondContact O-N 2.81Å; S200-L202 PolarHBondContact O-N 3.42Å
201N91.9Very high94.3Very high96 Ų9646 Ų4651%0.51326%0.256SS..  trans56.937.1-174.7-163.937.3000113.3S185 V187S185-N201 PolarHBondContact O-ND2 2.83Å; V187-N201 HydrophobicContact CG2-CB 4.26Å
202L92.5Very high94.4Very high2 Ų245.1 Ų45.11%0.0125%0.251CS..PPolyproline II helixtrans-83.6117.3-179.9-56.2-176000110.7Q156 A186 V199 S200 Y207 F209 V227 V229Q156-L202 PolarHBondContact N-O 3Å; A186-L202 HydrophobicContact CB-CD2 3.59Å; V199-L202 HydrophobicContact CG2-CD1 4.11Å; S200-L202 PolarHBondContact O-N 3.42Å; L202-Y207 HydrophobicContact CD2-CD1 4.11Å; L202-Y207 HydrophobicContact CD2-CE1 3.97Å; L202-Y207 HydrophobicContact CD2-CG 4.46Å; L202-F209 HydrophobicContact CD2-CZ 4.29Å; L202-V227 HydrophobicContact CD1-CG1 4.19Å; L202-V229 HydrophobicContact CB-CG2 3.8Å; L202-V229 HydrophobicContact CD1-CG2 4.12Å
203A92.4Very high94.5Very high44 Ų4438.7 Ų38.736%0.36421%0.211SC..PPolyproline II helixtrans-89.7155.4169.800000110.8G205 Y207A203-G205 PolarHBondContact O-N 3Å; A203-Y207 PolarHBondContact N-OH 2.79Å; A203-Y207 WeakPolarHBondContact O-CE2 3.44Å; A203-Y207 PolarHBondContact O-OH 2.77Å
204S93.3Very high94.6Very high55 Ų5535.9 Ų35.939%0.38520%0.201SC..SBendtrans-49132.6179.2-55.70000113P155 V229 L230P155-S204 WeakPolarHBondContact CG-OG 3.45Å; S204-V229 CarbonylContact C-O 3.59Å; S204-V229 WeakPolarHBondContact CA-O 3.33Å; S204-L230 WeakPolarHBondContact CB-O 3.38Å; S204-L230 PolarHBondContact OG-O 3.49Å
205G93.9Very high94.7Very high26 Ų2628.4 Ų28.427%0.26817%0.169SC..EExtended strand (participates in β ladder)trans145.2-178.6-172.700000113A203 V229A203-G205 PolarHBondContact O-N 3Å; G205-V229 PolarHBondContact N-O 3.41Å; G205-V229 PolarHBondContact O-N 3.46Å
206V95.2Very high94.7Very high80 Ų8030.8 Ų30.849%0.48519%0.187SC..EExtended strand (participates in β ladder)trans-102.9127.1179.8-177.20000109.7T226 L228V206-T226 HydrophobicContact CG1-CG2 3.5Å; V206-L228 HydrophobicContact CG2-CD1 3.96Å
207Y96.3Very high94.5Very high4 Ų432.8 Ų32.82%0.01621%0.205CC..EExtended strand (participates in β ladder)trans-114.7140.4174.1-58.8-107000108.9L179 S181 N183 A186 L202 A203 F209 T226 V227 V229L179-Y207 HydrophobicContact CD1-CD1 3.98Å; S181-Y207 CarbonylContact O-C 3.56Å; S181-Y207 VanDerWaalsContact O-CA 3.28Å; S181-Y207 WeakPolarHBondContact O-CA 3.46Å; N183-Y207 HydrophobicContact CB-CE1 3.85Å; N183-Y207 WeakPolarHBondContact CB-OH 3.22Å; N183-Y207 VanDerWaalsContact N-CE1 3.31Å; A186-Y207 HydrophobicContact CB-CD1 4.23Å; A186-Y207 HydrophobicContact CB-CE1 3.98Å; L202-Y207 HydrophobicContact CD2-CD1 4.11Å; L202-Y207 HydrophobicContact CD2-CE1 3.97Å; L202-Y207 HydrophobicContact CD2-CG 4.46Å; A203-Y207 PolarHBondContact N-OH 2.79Å; A203-Y207 WeakPolarHBondContact O-CE2 3.44Å; A203-Y207 PolarHBondContact O-OH 2.77Å; Y207-F209 HydrophobicContact CD1-CZ 4.46Å; Y207-F209 HydrophobicContact CG-CE2 4.37Å; Y207-T226 CarbonylContact O-C 3.59Å; Y207-T226 WeakPolarHBondContact O-CA 3.42Å; Y207-V227 PolarHBondContact N-O 3.42Å; Y207-V227 PolarHBondContact O-N 3.3Å; Y207-V229 HydrophobicContact CD2-CG2 3.68Å; Y207-V229 HydrophobicContact CE2-CB 4.22Å; Y207-V229 HydrophobicContact CE2-CG2 3.5Å
208K96.8Very high94.3Very high81 Ų8135.2 Ų35.235%0.35223%0.231SC..EExtended strand (participates in β ladder)trans-115.7118.8169.5-66.5-169.9170.6-160.20108.8V180 S181 I225V180-K208 HydrophobicContact CB-CB 4.3Å; V180-K208 PolarHBondContact N-O 3.31Å; S181-K208 PolarHBondContact N-O 3.38Å; S181-K208 PolarHBondContact O-N 3.41Å; S181-K208 WeakPolarHBondContact OG-CB 3.46Å; S181-K208 WeakPolarHBondContact OG-CG 3.15Å; K208-I225 WeakPolarHBondContact CA-O 3.49Å
209F96.5Very high94.2Very high0 Ų035.7 Ų35.70%023%0.232CC..EExtended strand (participates in β ladder)trans-106.1137.3173.8-64.2-84.9000108.7L161 W177 H178 L179 I188 V199 L202 Y207 Q224 I225 V227L161-F209 HydrophobicContact CD1-CB 4.1Å; L161-F209 HydrophobicContact CD1-CD1 4.38Å; L161-F209 HydrophobicContact CD1-CD2 4.08Å; L161-F209 HydrophobicContact CD1-CG 3.93Å; W177-F209 HydrophobicContact CE3-CB 4.12Å; W177-F209 HydrophobicContact CZ3-CB 4.16Å; H178-F209 WeakPolarHBondContact O-CA 3.32Å; L179-F209 HydrophobicContact CB-CD1 4.37Å; L179-F209 HydrophobicContact CB-CE1 4.27Å; L179-F209 HydrophobicContact CD1-CD1 4.06Å; L179-F209 HydrophobicContact CD1-CE1 3.7Å; L179-F209 HydrophobicContact CD1-CE2 4.48Å; L179-F209 HydrophobicContact CD1-CZ 3.93Å; I188-F209 HydrophobicContact CD1-CD1 3.99Å; I188-F209 HydrophobicContact CD1-CE1 3.91Å; I188-F209 HydrophobicContact CG1-CE1 4.15Å; V199-F209 HydrophobicContact CB-CE1 4.35Å; V199-F209 HydrophobicContact CB-CZ 4.05Å; V199-F209 HydrophobicContact CG1-CD1 4.28Å; V199-F209 HydrophobicContact CG1-CE1 3.79Å; V199-F209 HydrophobicContact CG1-CZ 3.96Å; V199-F209 HydrophobicContact CG2-CE2 4.38Å; V199-F209 HydrophobicContact CG2-CZ 4.24Å; L202-F209 HydrophobicContact CD2-CZ 4.29Å; Y207-F209 HydrophobicContact CD1-CZ 4.46Å; Y207-F209 HydrophobicContact CG-CE2 4.37Å; F209-Q224 WeakPolarHBondContact O-CA 3.38Å; F209-I225 HydrophobicContact CB-CG1 4.05Å; F209-I225 PolarHBondContact N-O 2.95Å; F209-I225 PolarHBondContact O-N 3.06Å; F209-V227 HydrophobicContact CD2-CB 4.39Å; F209-V227 HydrophobicContact CD2-CG2 3.74Å; F209-V227 HydrophobicContact CE2-CB 4.13Å; F209-V227 HydrophobicContact CE2-CG2 3.82Å
210Q96.8Very high94.1Very high21 Ų2138.6 Ų38.610%0.09825%0.253CS..EExtended strand (participates in β ladder)trans-113.1127.2177.3-178.6171.9-44.200109.7W177 H178 V180 T223 Q224W177-Q210 WeakPolarHBondContact CA-O 3.06Å; H178-Q210 PolarHBondContact N-O 2.87Å; H178-Q210 PolarHBondContact ND1-O 3.38Å; H178-Q210 PolarHBondContact O-N 3.48Å; V180-Q210 HydrophobicContact CG2-CB 3.44Å; V180-Q210 VanDerWaalsContact CG2-CB 3.44Å; V180-Q210 HydrophobicContact CG2-CG 4.46Å; Q210-T223 CarbonylContact C-O 3.55Å; Q210-T223 VanDerWaalsContact CA-O 3.3Å; Q210-T223 WeakPolarHBondContact CA-O 3.36Å; Q210-T223 WeakPolarHBondContact CG-O 3.48Å; Q210-Q224 HydrophobicContact CB-CG 4.05Å; Q210-Q224 HydrophobicContact CG-CG 4.06Å
211L96.5Very high94.1Very high0 Ų040.3 Ų40.30%026%0.26CS..EExtended strand (participates in β ladder)trans-94.7127.6168.3168.361.7000108.1Y175 W177 V213 Q222 T223Y175-L211 HydrophobicContact CD1-CD1 4.12Å; W177-L211 HydrophobicContact CD2-CB 4.01Å; W177-L211 HydrophobicContact CD2-CD1 4.24Å; W177-L211 HydrophobicContact CE3-CB 3.9Å; W177-L211 HydrophobicContact CG-CD1 4.42Å; W177-L211 HydrophobicContact CH2-CB 3.84Å; W177-L211 HydrophobicContact CH2-CD2 4.38Å; W177-L211 HydrophobicContact CZ2-CB 3.92Å; W177-L211 HydrophobicContact CZ2-CD1 4.32Å; W177-L211 HydrophobicContact CZ2-CD2 3.94Å; W177-L211 HydrophobicContact CZ2-CG 4.27Å; W177-L211 HydrophobicContact CZ3-CB 3.82Å; L211-V213 HydrophobicContact CD1-CG2 4.05Å; L211-V213 HydrophobicContact CD2-CG2 3.93Å; L211-V213 HydrophobicContact CG-CG2 3.83Å; L211-Q222 VanDerWaalsContact O-CA 3.31Å; L211-Q222 WeakPolarHBondContact O-CA 3.33Å; L211-T223 HydrophobicContact CB-CG2 3.93Å; L211-T223 HydrophobicContact CD2-CG2 4.24Å; L211-T223 HydrophobicContact CG-CG2 4.38Å; L211-T223 PolarHBondContact N-O 2.94Å; L211-T223 PolarHBondContact O-N 3.44Å
212T96.4Very high94.2Very high16 Ų1640.9 Ų40.910%0.09826%0.259CS..EExtended strand (participates in β ladder)trans-109.7129.3164.4-61.10000108.9L176 D221 Q222L176-T212 PolarHBondContact N-O 2.84Å; L176-T212 PolarHBondContact O-N 2.03Å; T212-D221 WeakPolarHBondContact CA-O 3.13Å; T212-Q222 HydrophobicContact CG2-CG 3.99Å
213V95.6Very high94.2Very high0 Ų042.7 Ų42.70%027%0.27CS..EExtended strand (participates in β ladder)trans-109.6146.7177.4-178.10000108.5P143 A145 I172 Y175 L211 S220 D221P143-V213 HydrophobicContact CB-CG1 3.94Å; P143-V213 HydrophobicContact CG-CG1 4.25Å; A145-V213 HydrophobicContact CB-CB 4.07Å; A145-V213 HydrophobicContact CB-CG2 3.63Å; I172-V213 HydrophobicContact CB-CG1 4.34Å; I172-V213 HydrophobicContact CD1-CG1 3.85Å; I172-V213 HydrophobicContact CG1-CG1 3.96Å; I172-V213 HydrophobicContact CG2-CG1 3.43Å; I172-V213 VanDerWaalsContact CG2-CG1 3.43Å; Y175-V213 HydrophobicContact CD1-CG2 4.07Å; Y175-V213 HydrophobicContact CE1-CG2 4.32Å; L211-V213 HydrophobicContact CD1-CG2 4.05Å; L211-V213 HydrophobicContact CD2-CG2 3.93Å; L211-V213 HydrophobicContact CG-CG2 3.83Å; V213-S220 WeakPolarHBondContact O-CA 3.22Å; V213-S220 WeakPolarHBondContact O-CB 3.48Å; V213-D221 PolarHBondContact N-O 3.41Å; V213-D221 PolarHBondContact O-N 3.03Å
214T94.5Very high94.3Very high32 Ų3244.2 Ų44.220%0.19627%0.27CS..EExtended strand (participates in β ladder)trans-141133.6176.3-43.40000110.3V173 T174 Q219V173-T214 WeakPolarHBondContact CG2-O 3.44Å; V173-T214 PolarHBondContact N-O 3.05Å; T174-T214 PolarHBondContact N-O 2.77Å; T174-T214 PolarHBondContact O-N 2.67Å; T174-T214 WeakPolarHBondContact OG1-CB 3.15Å; T174-T214 PolarHBondContact OG1-OG1 3.43Å; T214-Q219 VanDerWaalsContact CA-O 3.27Å; T214-Q219 WeakPolarHBondContact CA-O 3.38Å; T214-Q219 WeakPolarHBondContact CG2-O 3.21Å
215D93.9Very high94.3Very high1 Ų141.7 Ų41.71%0.00525%0.252CS..  trans-79.1179.4179.469.415.3000112.5P143 D168 V173 S217 G218 Q219P143-D215 HydrophobicContact CG-CB 4.28Å; D168-D215 VanDerWaalsContact OD2-CB 3.23Å; D168-D215 WeakPolarHBondContact OD2-CB 3.23Å; V173-D215 WeakPolarHBondContact CG2-O 3.3Å; D215-S217 PolarHBondContact O-N 3.38Å; D215-S217 VanDerWaalsContact OD1-C 3.3Å; D215-S217 WeakPolarHBondContact OD1-CA 3.47Å; D215-S217 PolarHBondContact OD1-N 3.36Å; D215-G218 WeakPolarHBondContact OD1-CA 3.08Å; D215-G218 PolarHBondContact OD1-N 3.25Å; D215-Q219 PolarHBondContact N-O 3.08Å; D215-Q219 PolarHBondContact OD1-N 3.25Å; D215-Q219 WeakPolarHBondContact OD2-CB 3.21Å; D215-Q219 VanDerWaalsContact OD2-CG 3.23Å; D215-Q219 WeakPolarHBondContact OD2-CG 3.31Å; D215-Q219 PolarHBondContact OD2-NE2 3.29Å
216S92.2Very high94.4Very high68 Ų6841.8 Ų41.848%0.47625%0.248SC..THydrogen-bonded Turntrans-70.1-13.3176.471.30000115.2D171D171-S216 PolarHBondContact O-N 3.03Å; D171-S216 VanDerWaalsContact O-N 3.08Å
217S90Very high94.5Very high74 Ų7438 Ų3852%0.51723%0.225SC..THydrogen-bonded Turntrans-98.9-12.1-177.7-65.70000113.9D140 D215D140-S217 WeakPolarHBondContact OD2-CB 3.48Å; D140-S217 PolarHBondContact OD2-OG 2.68Å; D215-S217 PolarHBondContact O-N 3.38Å; D215-S217 VanDerWaalsContact OD1-C 3.3Å; D215-S217 WeakPolarHBondContact OD1-CA 3.47Å; D215-S217 PolarHBondContact OD1-N 3.36Å
218G91.1Very high94.4Very high59 Ų5939.4 Ų39.461%0.60823%0.232SC*.SBendtrans95.39.2-177.700000115.7D215D215-G218 WeakPolarHBondContact OD1-CA 3.08Å; D215-G218 PolarHBondContact OD1-N 3.25Å
219Q93Very high94.3Very high63 Ų6335.6 Ų35.629%0.29422%0.216SC..  trans-80.4153.1170.1-41174.595.200109.9D140 N141 P142 T214 D215D140-Q219 VanDerWaalsContact CG-NE2 3.26Å; D140-Q219 PolarHBondContact OD1-NE2 3.22Å; D140-Q219 PolarHBondContact OD2-NE2 3.4Å; N141-Q219 PolarHBondContact O-NE2 3.06Å; P142-Q219 HydrophobicContact CB-CB 4.15Å; T214-Q219 VanDerWaalsContact CA-O 3.27Å; T214-Q219 WeakPolarHBondContact CA-O 3.38Å; T214-Q219 WeakPolarHBondContact CG2-O 3.21Å; D215-Q219 PolarHBondContact N-O 3.08Å; D215-Q219 PolarHBondContact OD1-N 3.25Å; D215-Q219 WeakPolarHBondContact OD2-CB 3.21Å; D215-Q219 VanDerWaalsContact OD2-CG 3.23Å; D215-Q219 WeakPolarHBondContact OD2-CG 3.31Å; D215-Q219 PolarHBondContact OD2-NE2 3.29Å
220S93.9Very high94.2Very high62 Ų6235.6 Ų35.643%0.43422%0.216SC..EExtended strand (participates in β ladder)trans-147.8144.6-174.368.60000113.2V213V213-S220 WeakPolarHBondContact O-CA 3.22Å; V213-S220 WeakPolarHBondContact O-CB 3.48Å
221D93.6Very high94Very high63 Ų6336.7 Ų36.734%0.33722%0.224SC..EExtended strand (participates in β ladder)trans-126.4162.7171.9-178.541.5000111.3P143 A145 T212 V213P143-D221 WeakPolarHBondContact O-CB 3.4Å; A145-D221 HydrophobicContact CB-CB 4.12Å; A145-D221 VanDerWaalsContact CB-OD2 3.29Å; A145-D221 WeakPolarHBondContact CB-OD2 3.42Å; A145-D221 PolarHBondContact N-OD2 3.22Å; T212-D221 WeakPolarHBondContact CA-O 3.13Å; V213-D221 PolarHBondContact N-O 3.41Å; V213-D221 PolarHBondContact O-N 3.03Å
222Q94.2Very high93.6Very high107 Ų10741.2 Ų41.250%0.525%0.254SS..EExtended strand (participates in β ladder)trans-142.3127.3-168.4-50.8-172.5-1.600112.1L211 T212L211-Q222 VanDerWaalsContact O-CA 3.31Å; L211-Q222 WeakPolarHBondContact O-CA 3.33Å; T212-Q222 HydrophobicContact CG2-CG 3.99Å
223T92.6Very high93.2Very high40 Ų4047.5 Ų47.525%0.24528%0.282CS..EExtended strand (participates in β ladder)trans-127.6151.2177.9-172.20000111.5A145 Q210 L211A145-T223 HydrophobicContact CB-CG2 3.86Å; A145-T223 VanDerWaalsContact O-CB 3.23Å; A145-T223 WeakPolarHBondContact O-CB 3.2Å; A145-T223 VanDerWaalsContact O-CG2 3.24Å; A145-T223 WeakPolarHBondContact O-CG2 3.46Å; Q210-T223 CarbonylContact C-O 3.55Å; Q210-T223 VanDerWaalsContact CA-O 3.3Å; Q210-T223 WeakPolarHBondContact CA-O 3.36Å; Q210-T223 WeakPolarHBondContact CG-O 3.48Å; L211-T223 HydrophobicContact CB-CG2 3.93Å; L211-T223 HydrophobicContact CD2-CG2 4.24Å; L211-T223 HydrophobicContact CG-CG2 4.38Å; L211-T223 PolarHBondContact N-O 2.94Å; L211-T223 PolarHBondContact O-N 3.44Å
224Q94.3Very high93Very high76 Ų7650.7 Ų50.736%0.35530%0.297SS..EExtended strand (participates in β ladder)trans-119.4131.2-179.6-66.2-168.3-1.900111.5F209 Q210F209-Q224 WeakPolarHBondContact O-CA 3.38Å; Q210-Q224 HydrophobicContact CB-CG 4.05Å; Q210-Q224 HydrophobicContact CG-CG 4.06Å
225I94.4Very high92.8Very high3 Ų349.4 Ų49.42%0.01529%0.289CS..EExtended strand (participates in β ladder)trans-112.3147.6170.870.2173000110.4G148 L161 W177 K208 F209G148-I225 VanDerWaalsContact O-CG2 3.25Å; G148-I225 WeakPolarHBondContact O-CG2 3.01Å; L161-I225 HydrophobicContact CD1-CD1 3.93Å; L161-I225 HydrophobicContact CD2-CD1 3.53Å; L161-I225 HydrophobicContact CG-CD1 4.19Å; W177-I225 HydrophobicContact CH2-CD1 3.86Å; W177-I225 HydrophobicContact CH2-CG1 4.47Å; W177-I225 HydrophobicContact CZ3-CD1 3.75Å; W177-I225 HydrophobicContact CZ3-CG1 4.04Å; K208-I225 WeakPolarHBondContact CA-O 3.49Å; F209-I225 HydrophobicContact CB-CG1 4.05Å; F209-I225 PolarHBondContact N-O 2.95Å; F209-I225 PolarHBondContact O-N 3.06Å
226T95.5Very high92.6Very high28 Ų2852 Ų5217%0.17230%0.301CS..EExtended strand (participates in β ladder)trans-103128.2175.3-52.50000109.9D150 R151 V206 Y207D150-T226 CarbonylContact C-O 3.57Å; D150-T226 WeakPolarHBondContact CA-O 2.97Å; D150-T226 WeakPolarHBondContact CB-O 3.23Å; D150-T226 WeakPolarHBondContact OD1-CA 3.2Å; D150-T226 WeakPolarHBondContact OD1-CB 3.13Å; D150-T226 PolarHBondContact OD1-N 2.76Å; R151-T226 PolarHBondContact N-O 3.44Å; V206-T226 HydrophobicContact CG1-CG2 3.5Å; Y207-T226 CarbonylContact O-C 3.59Å; Y207-T226 WeakPolarHBondContact O-CA 3.42Å
227V95.7Very high92.4Very high0 Ų051.6 Ų51.60%029%0.294CS..EExtended strand (participates in β ladder)trans-110.9108.1170.1-178.10000107.9R151 V153 L159 L202 Y207 F209 V229R151-V227 HydrophobicContact CB-CG1 4.38Å; R151-V227 HydrophobicContact CB-CG2 4.26Å; R151-V227 CarbonylContact O-C 3.46Å; R151-V227 WeakPolarHBondContact O-CA 3.35Å; V153-V227 HydrophobicContact CG1-CG1 4.46Å; V153-V227 HydrophobicContact CG2-CG1 3.93Å; L159-V227 HydrophobicContact CD2-CB 4.4Å; L159-V227 HydrophobicContact CD2-CG1 3.72Å; L159-V227 HydrophobicContact CD2-CG2 3.72Å; L202-V227 HydrophobicContact CD1-CG1 4.19Å; Y207-V227 PolarHBondContact N-O 3.42Å; Y207-V227 PolarHBondContact O-N 3.3Å; F209-V227 HydrophobicContact CD2-CB 4.39Å; F209-V227 HydrophobicContact CD2-CG2 3.74Å; F209-V227 HydrophobicContact CE2-CB 4.13Å; F209-V227 HydrophobicContact CE2-CG2 3.82Å; V227-V229 HydrophobicContact CG1-CG2 4.28Å
228L95.3Very high92.6Very high34 Ų3449.1 Ų49.118%0.17827%0.274CS..EExtended strand (participates in β ladder)trans-87.2112.5171.217462000109R151 V152 V153 V206 L230R151-L228 PolarHBondContact O-N 2.9Å; V152-L228 WeakPolarHBondContact CA-O 3.46Å; V152-L228 HydrophobicContact CG2-CB 4.5Å; V152-L228 HydrophobicContact CG2-CD2 4.49Å; V153-L228 PolarHBondContact N-O 2.98Å; V206-L228 HydrophobicContact CG2-CD1 3.96Å; L228-L230 HydrophobicContact CD2-CD2 4.05Å; L228-L230 HydrophobicContact CG-CD2 4.24Å
229V95.1Very high92.7Very high0 Ų046.3 Ų46.30%025%0.245CC..EExtended strand (participates in β ladder)trans-94.7113.2172.2-172.30000107.2V153 P155 L202 S204 G205 Y207 V227V153-V229 HydrophobicContact CG2-CB 4.24Å; V153-V229 HydrophobicContact CG2-CG1 4.31Å; V153-V229 HydrophobicContact CG2-CG2 3.78Å; V153-V229 WeakPolarHBondContact O-CA 2.95Å; P155-V229 HydrophobicContact CB-CG1 4.15Å; P155-V229 HydrophobicContact CG-CG1 4.06Å; L202-V229 HydrophobicContact CB-CG2 3.8Å; L202-V229 HydrophobicContact CD1-CG2 4.12Å; S204-V229 CarbonylContact C-O 3.59Å; S204-V229 WeakPolarHBondContact CA-O 3.33Å; G205-V229 PolarHBondContact N-O 3.41Å; G205-V229 PolarHBondContact O-N 3.46Å; Y207-V229 HydrophobicContact CD2-CG2 3.68Å; Y207-V229 HydrophobicContact CE2-CB 4.22Å; Y207-V229 HydrophobicContact CE2-CG2 3.5Å; V227-V229 HydrophobicContact CG1-CG2 4.28Å
230L94Very high92.5Very high0 Ų046.3 Ų46.30%025%0.246CC..  trans-63.6141.8-167.3-67169.5000112.5V152 V153 P155 S204 L228 Q234 S235 H238 A288V152-L230 HydrophobicContact CG1-CD1 3.7Å; V152-L230 HydrophobicContact CG1-CD2 3.7Å; V152-L230 HydrophobicContact CG1-CG 3.7Å; V153-L230 PolarHBondContact O-N 3.19Å; P155-L230 WeakPolarHBondContact CG-O 3.17Å; S204-L230 WeakPolarHBondContact CB-O 3.38Å; S204-L230 PolarHBondContact OG-O 3.49Å; L228-L230 HydrophobicContact CD2-CD2 4.05Å; L228-L230 HydrophobicContact CG-CD2 4.24Å; L230-Q234 HydrophobicContact CB-CB 4.37Å; L230-Q234 HydrophobicContact CD2-CB 3.58Å; L230-S235 WeakPolarHBondContact CB-OG 3.42Å; L230-H238 HydrophobicContact CD1-CB 3.87Å; L230-H238 HydrophobicContact CD2-CB 4.28Å; L230-H238 VanDerWaalsContact CD2-CD2 3.4Å; L230-H238 WeakPolarHBondContact CD2-CD2 3.23Å; L230-A288 VanDerWaalsContact CD1-O 3.29Å; L230-A288 WeakPolarHBondContact CD1-O 3.3Å
231T92.1Very high92.3Very high45 Ų4545.2 Ų45.228%0.27624%0.236SC..  trans-78.8162.8159.970.30000109.9E233 Q234 S235T231-E233 PolarHBondContact O-N 3.03Å; T231-Q234 PolarHBondContact O-N 3.17Å; T231-Q234 VanDerWaalsContact O-N 3.12Å; T231-Q234 WeakPolarHBondContact OG1-CG 3.47Å; T231-Q234 PolarHBondContact OG1-N 3.37Å; T231-Q234 VanDerWaalsContact OG1-N 3.12Å; T231-S235 PolarHBondContact O-N 2.72Å; T231-S235 PolarHBondContact O-OG 3.11Å
232P88.7Confident92.2Very high95 Ų9547.3 Ų47.362%0.61725%0.253SS*.Hα-helixtrans-54.2-38.3173.5-27.936.3000113.4S235 E236P232-S235 WeakPolarHBondContact O-CB 3.34Å; P232-S235 PolarHBondContact O-N 3.44Å; P232-E236 PolarHBondContact O-N 3.28Å
233E87.2Confident92.2Very high148 Ų14846.5 Ų46.569%0.69225%0.248SC*.Hα-helixtrans-67.1-42.6176.4-179.1176.8-166.600112.2T231 S235 E236T231-E233 PolarHBondContact O-N 3.03Å; E233-S235 VanDerWaalsContact C-N 3.3Å; E233-S235 PolarHBondContact O-N 2.93Å; E233-E236 WeakPolarHBondContact O-CB 2.94Å; E233-E236 PolarHBondContact O-N 3.29Å
234Q91.3Very high92.3Very high67 Ų6745.3 Ų45.331%0.31324%0.24SC..Hα-helixtrans-67.4-33175.1-66.7172.5-44.500111.9L230 T231 E236 N237 H238L230-Q234 HydrophobicContact CB-CB 4.37Å; L230-Q234 HydrophobicContact CD2-CB 3.58Å; T231-Q234 PolarHBondContact O-N 3.17Å; T231-Q234 VanDerWaalsContact O-N 3.12Å; T231-Q234 WeakPolarHBondContact OG1-CG 3.47Å; T231-Q234 PolarHBondContact OG1-N 3.37Å; T231-Q234 VanDerWaalsContact OG1-N 3.12Å; Q234-E236 VanDerWaalsContact C-N 3.27Å; Q234-E236 PolarHBondContact O-N 3.42Å; Q234-N237 PolarHBondContact O-N 3.19Å; Q234-H238 WeakPolarHBondContact O-CB 3.29Å; Q234-H238 PolarHBondContact O-CD2 3.29Å; Q234-H238 PolarHBondContact O-N 2.69Å
235S91.4Very high92.3Very high5 Ų545.2 Ų45.24%0.03524%0.244CC..Hα-helixtrans-64.1-27.9173-620000112.9Q154 L230 T231 P232 E233 C239 M240Q154-S235 PolarHBondContact NE2-OG 2.94Å; Q154-S235 PolarHBondContact OE1-OG 3.16Å; L230-S235 WeakPolarHBondContact CB-OG 3.42Å; T231-S235 PolarHBondContact O-N 2.72Å; T231-S235 PolarHBondContact O-OG 3.11Å; P232-S235 WeakPolarHBondContact O-CB 3.34Å; P232-S235 PolarHBondContact O-N 3.44Å; E233-S235 VanDerWaalsContact C-N 3.3Å; E233-S235 PolarHBondContact O-N 2.93Å; S235-C239 VanDerWaalsContact O-CB 3.32Å; S235-C239 WeakPolarHBondContact O-CB 3.5Å; S235-C239 PolarHBondContact O-N 3.42Å; S235-M240 PolarHBondContact O-N 2.89Å
236E88.6Confident92.3Very high54 Ų5446 Ų4625%0.25225%0.253SS..Iπ-helixtrans-58.3-49.6170.6-63.1-179.6-17400109.5P232 E233 Q234 M240 V241 R299P232-E236 PolarHBondContact O-N 3.28Å; E233-E236 WeakPolarHBondContact O-CB 2.94Å; E233-E236 PolarHBondContact O-N 3.29Å; Q234-E236 VanDerWaalsContact C-N 3.27Å; Q234-E236 PolarHBondContact O-N 3.42Å; E236-M240 HydrophobicContact CG-SD 4.16Å; E236-M240 CarbonylContact O-C 3.59Å; E236-M240 WeakPolarHBondContact O-CA 3.47Å; E236-M240 WeakPolarHBondContact O-CB 3.37Å; E236-M240 PolarHBondContact O-N 3.01Å; E236-V241 PolarHBondContact O-N 2.01Å; E236-R299 IonicContact OE1-NH1 3.51Å
237N89.4Confident92.2Very high61 Ų6145.9 Ų45.933%0.32625%0.252SS..Iπ-helixtrans-78.6-29.1-178.4-67.7-15000115Q234 V241 L276Q234-N237 PolarHBondContact O-N 3.19Å; N237-V241 WeakPolarHBondContact O-CG2 3.39Å; N237-L276 HydrophobicContact CB-CD1 4.18Å; N237-L276 WeakPolarHBondContact O-CB 3.43Å
238H93.1Very high92.2Very high21 Ų2146 Ų4610%0.09725%0.253CS..Iπ-helixtrans-86-24.6-179.9-88-82.9000114.1L230 Q234 L276 N277 Y279 C289L230-H238 HydrophobicContact CD1-CB 3.87Å; L230-H238 HydrophobicContact CD2-CB 4.28Å; L230-H238 VanDerWaalsContact CD2-CD2 3.4Å; L230-H238 WeakPolarHBondContact CD2-CD2 3.23Å; Q234-H238 WeakPolarHBondContact O-CB 3.29Å; Q234-H238 PolarHBondContact O-CD2 3.29Å; Q234-H238 PolarHBondContact O-N 2.69Å; H238-L276 PolarHBondContact ND1-O 2.86Å; H238-N277 WeakPolarHBondContact O-CA 3.23Å; H238-N277 WeakPolarHBondContact O-CB 3.24Å; H238-N277 PolarHBondContact O-OD1 3.14Å; H238-Y279 PolarHBondContact ND1-OH 2.83Å; H238-Y279 PolarHBondContact O-OH 3.37Å; H238-C289 PolarHBondContact O-SG 2.03Å
239C93.3Very high92Very high1 Ų152.4 Ų52.41%0.00728%0.275CS..Iπ-helixtrans-133.1-36-169.5-52.90000114S235 Y257 N277 A288 C289 V292S235-C239 VanDerWaalsContact O-CB 3.32Å; S235-C239 WeakPolarHBondContact O-CB 3.5Å; S235-C239 PolarHBondContact O-N 3.42Å; C239-Y257 HydrophobicContact CB-CD1 3.94Å; C239-Y257 HydrophobicContact CB-CG 4.37Å; C239-Y257 WeakPolarHBondContact O-CD1 3.23Å; C239-N277 PolarHBondContact O-ND2 3.19Å; C239-A288 PolarHBondContact SG-O 2.82Å; C239-C289 VanDerWaalsContact CA-SG 3.51Å; C239-C289 HydrophobicContact CB-CB 3.72Å; C239-C289 WeakPolarHBondContact CB-SG 3Å; C239-C289 WeakPolarHBondContact SG-CA 3.37Å; C239-C289 WeakPolarHBondContact SG-CB 3.31Å; C239-C289 CovalentContact SG-SG 2.03Å; C239-C289 PolarHBondContact SG-SG 2.02Å; C239-V292 HydrophobicContact CB-CB 4.5Å; C239-V292 HydrophobicContact CB-CG1 4.15Å
240M89.4Confident91.9Very high63 Ų6353 Ų5331%0.3128%0.281SS..Iπ-helixtrans-90.8-23-173.3-54.6-172.7-177.900113.9S235 E236 V292S235-M240 PolarHBondContact O-N 2.89Å; E236-M240 HydrophobicContact CG-SD 4.16Å; E236-M240 CarbonylContact O-C 3.59Å; E236-M240 WeakPolarHBondContact O-CA 3.47Å; E236-M240 WeakPolarHBondContact O-CB 3.37Å; E236-M240 PolarHBondContact O-N 3.01Å; M240-V292 HydrophobicContact CE-CG1 3.54Å; M240-V292 HydrophobicContact CG-CG1 4.41Å
241V89.6Confident91.9Very high39 Ų3956.9 Ų56.924%0.23631%0.308CS..SBendtrans-63.8143.1172.8-64.30000111.4E236 N237 N275 N277E236-V241 PolarHBondContact O-N 2.01Å; N237-V241 WeakPolarHBondContact O-CG2 3.39Å; V241-N275 WeakPolarHBondContact CG2-ND2 3.31Å; V241-N277 HydrophobicContact CG2-CB 3.58Å; V241-N277 PolarHBondContact O-ND2 2.61Å
242P91.6Very high92.1Very high106 Ų10655 Ų5569%0.68830%0.296SS*.PPolyproline II helixtrans-59.5157.1174.7-23.434000113K244 N275P242-K244 PolarHBondContact O-N 2.83Å; P242-N275 PolarHBondContact O-ND2 3.41Å
243K94.2Very high92.4Very high90 Ų9053.4 Ų53.439%0.39129%0.286SS..PPolyproline II helixtrans-57.2128.1168.142.6163.1161.1-104.40111.4H256 F267K243-H256 HydrophobicContact CB-CB 4.14Å; K243-H256 WeakPolarHBondContact CD-NE2 3.3Å; K243-H256 PolarHBondContact NZ-NE2 3.03Å; K243-F267 HydrophobicContact CB-CD1 4.37Å; K243-F267 HydrophobicContact CB-CD2 4.03Å; K243-F267 HydrophobicContact CB-CE1 4.47Å; K243-F267 HydrophobicContact CB-CE2 4.14Å; K243-F267 HydrophobicContact CB-CG 4.15Å; K243-F267 HydrophobicContact CB-CZ 4.35Å; K243-F267 HydrophobicContact CD-CB 3.66Å; K243-F267 HydrophobicContact CD-CD2 4.06Å; K243-F267 HydrophobicContact CD-CG 3.91Å
244K94.8Very high92.9Very high16 Ų1646.7 Ų46.77%0.0725%0.254CS..  trans-105.9114.5175.2-175.4165.3178.5169.30110.8P242 G246 F267 R273 N275 G330 L331 E332 C333 D334P242-K244 PolarHBondContact O-N 2.83Å; K244-G246 VanDerWaalsContact C-N 3.3Å; K244-F267 WeakPolarHBondContact O-CE2 3.39Å; K244-R273 WeakPolarHBondContact CD-O 3.29Å; K244-R273 WeakPolarHBondContact CE-O 3.41Å; K244-N275 HydrophobicContact CB-CB 4.22Å; K244-N275 HydrophobicContact CD-CB 4.26Å; K244-G330 VanDerWaalsContact CD-O 3.26Å; K244-G330 WeakPolarHBondContact CD-O 3.25Å; K244-G330 PolarHBondContact NZ-O 2.81Å; K244-L331 PolarHBondContact NZ-O 3.14Å; K244-E332 WeakPolarHBondContact CE-O 3.32Å; K244-E332 PolarHBondContact NZ-O 2.87Å; K244-C333 VanDerWaalsContact CE-O 3.28Å; K244-C333 WeakPolarHBondContact CE-O 3.16Å; K244-D334 HydrophobicContact CD-CB 4.4Å
245V94.8Very high93.2Very high74 Ų7446.4 Ų46.445%0.44825%0.251SS..  trans-69.7-31.8173.1-179.90000110.9F269 G270V245-F269 WeakPolarHBondContact O-CD2 3.44Å; V245-G270 VanDerWaalsContact O-CA 3.3Å; V245-G270 WeakPolarHBondContact O-CA 3.36Å; V245-G270 PolarHBondContact O-N 3.37Å
246G93.3Very high93.5Very high19 Ų1946.5 Ų46.520%0.19625%0.25CS..  trans79.5177.1-171.400000112.7K244K244-G246 VanDerWaalsContact C-N 3.3Å
247P94.6Very high93.9Very high26 Ų2644.2 Ų44.217%0.16924%0.239CC..SBendtrans-83.4-23.8-177.633.4-35.8000113.3R273 C333 C348 L351 N352P247-R273 HydrophobicContact CG-CB 4.5Å; P247-R273 HydrophobicContact CG-CG 4.17Å; P247-C333 HydrophobicContact CB-CB 4.08Å; P247-C333 HydrophobicContact CG-CB 3.7Å; P247-C348 HydrophobicContact CB-CB 3.89Å; P247-C348 HydrophobicContact CG-CB 4.37Å; P247-L351 HydrophobicContact CG-CD2 4.06Å; P247-N352 WeakPolarHBondContact O-CB 3.32Å
248C94.8Very high94.1Very high2 Ų243.3 Ų43.31%0.01424%0.235CC..SBendtrans-68.1147178.2-67.70000111.8G270 C272 F355C248-G270 CarbonylContact C-O 3.58Å; C248-G270 WeakPolarHBondContact CB-O 3.49Å; C248-G270 WeakPolarHBondContact O-CA 3.03Å; C248-C272 HydrophobicContact CB-CB 4.01Å; C248-C272 WeakPolarHBondContact CB-SG 3.36Å; C248-C272 WeakPolarHBondContact SG-CB 3.49Å; C248-C272 CovalentContact SG-SG 2.03Å; C248-C272 PolarHBondContact SG-SG 2.96Å; C248-F355 HydrophobicContact CB-CB 4.33Å; C248-F355 HydrophobicContact CB-CD1 3.62Å; C248-F355 HydrophobicContact CB-CE1 4.15Å; C248-F355 HydrophobicContact CB-CG 4.1Å; C248-F355 VanDerWaalsContact SG-CB 3.55Å
249R92.2Very high93.8Very high168 Ų16843.1 Ų43.163%0.63424%0.237SC*.  trans-106.840.1-177.9-60.3180-167.9-173.14.1114E349 N352 Q356R249-E349 IonicContact NH2-OE1 2.84Å; R249-N352 WeakPolarHBondContact CG-OD1 3.46Å; R249-N352 PolarHBondContact N-OD1 3.08Å; R249-N352 VanDerWaalsContact N-OD1 3.09Å; R249-N352 PolarHBondContact NE-ND2 3.24Å; R249-Q356 PolarHBondContact O-NE2 2.75Å; R249-Q356 VanDerWaalsContact O-NE2 3.11Å
250G92.2Very high93.6Very high12 Ų1247.7 Ų47.712%0.12427%0.274CS..  trans-73.2-173.3163.600000112.2G270G250-G270 VanDerWaalsContact CA-O 3.31Å; G250-G270 WeakPolarHBondContact CA-O 3.37Å; G250-G270 PolarHBondContact N-O 2.82Å
251S94.2Very high93.7Very high83 Ų8346.7 Ų46.758%0.5827%0.274SS*.  trans-147.565.8179.9-71.20000111.2
252F95.7Very high93.7Very high4 Ų449.8 Ų49.82%0.01829%0.286CS..EExtended strand (participates in β ladder)trans-95120.3-176.8-53.7-70.7000110D48 V51 K52 R254 F269 F355 L359D48-F252 VanDerWaalsContact O-CE1 3.28Å; D48-F252 WeakPolarHBondContact O-CE1 3.31Å; D48-F252 WeakPolarHBondContact OD1-CE1 3.23Å; V51-F252 HydrophobicContact CB-CD1 4.36Å; V51-F252 HydrophobicContact CB-CD2 4.48Å; V51-F252 HydrophobicContact CB-CE1 4.01Å; V51-F252 HydrophobicContact CB-CE2 4.12Å; V51-F252 HydrophobicContact CB-CZ 3.87Å; V51-F252 HydrophobicContact CG1-CD1 4.13Å; V51-F252 HydrophobicContact CG1-CD2 3.55Å; V51-F252 HydrophobicContact CG1-CE1 4.09Å; V51-F252 HydrophobicContact CG1-CE2 3.49Å; V51-F252 VanDerWaalsContact CG1-CE2 3.49Å; V51-F252 HydrophobicContact CG1-CG 3.88Å; V51-F252 HydrophobicContact CG1-CZ 3.78Å; K52-F252 HydrophobicContact CB-CD1 4Å; K52-F252 HydrophobicContact CB-CE1 4.46Å; F252-R254 PolarHBondContact O-N 3.08Å; F252-F269 WeakPolarHBondContact CD2-O 3.36Å; F252-F269 PolarHBondContact N-O 2.99Å; F252-F269 PolarHBondContact O-N 3.23Å; F252-F355 AromaticContact CE2-CE1 3.93Å; F252-F355 HydrophobicContact CE2-CE1 3.93Å; F252-F355 AromaticContact CE2-CZ 3.78Å; F252-F355 HydrophobicContact CE2-CZ 3.78Å; F252-F355 HydrophobicContact CZ-CE1 4.38Å; F252-F355 HydrophobicContact CZ-CZ 4.05Å; F252-L359 HydrophobicContact CZ-CD2 4.24Å
253P96Very high93.8Very high63 Ų6353.1 Ų53.141%0.40929%0.285SS..EExtended strand (participates in β ladder)trans-66.3128.1176.127.9-33.5000109.7E266P253-E266 VanDerWaalsContact CB-OE1 3.29Å; P253-E266 WeakPolarHBondContact CB-OE1 3.31Å
254R97.3Very high94Very high6 Ų650 Ų502%0.02327%0.273CS..EExtended strand (participates in β ladder)trans-139.7159178.8-64.4-65-177.289.2-3.8109.4V51 F252 E266 F267 F269 N278V51-R254 PolarHBondContact O-NH2 2.83Å; F252-R254 PolarHBondContact O-N 3.08Å; R254-E266 CarbonylContact O-C 3.01Å; R254-E266 WeakPolarHBondContact O-CA 3.41Å; R254-F267 HydrophobicContact CB-CD1 4.06Å; R254-F267 HydrophobicContact CB-CE1 3.55Å; R254-F267 HydrophobicContact CB-CZ 3.99Å; R254-F267 PolarHBondContact N-O 3.16Å; R254-F267 VanDerWaalsContact O-CD1 3.32Å; R254-F267 WeakPolarHBondContact O-CD1 3.43Å; R254-F267 PolarHBondContact O-N 2.92Å; R254-F269 HydrophobicContact CB-CB 4.21Å; R254-F269 HydrophobicContact CG-CB 3.52Å; R254-F269 HydrophobicContact CG-CD1 4.28Å; R254-F269 HydrophobicContact CG-CG 4.23Å; R254-N278 WeakPolarHBondContact CB-OD1 3.08Å; R254-N278 VanDerWaalsContact CD-OD1 3.31Å; R254-N278 WeakPolarHBondContact CD-OD1 3.48Å; R254-N278 VanDerWaalsContact CG-OD1 3.23Å; R254-N278 WeakPolarHBondContact CG-OD1 3.29Å; R254-N278 PolarHBondContact NH1-OD1 3.24Å
255W97.7Very high94.1Very high62 Ų6252 Ų5224%0.23528%0.283CS..EExtended strand (participates in β ladder)trans-103.8142.7173.9-67.581.2000110.1C264 E265 E266 Y279 S281 L282 C285W255-C264 HydrophobicContact CE3-CB 4.1Å; W255-E265 WeakPolarHBondContact CA-O 3.25Å; W255-E266 HydrophobicContact CH2-CB 4.4Å; W255-E266 HydrophobicContact CZ2-CB 4.39Å; W255-E266 HydrophobicContact CZ3-CB 4.45Å; W255-Y279 PolarHBondContact N-O 3.45Å; W255-Y279 PolarHBondContact O-N 2.92Å; W255-S281 VanDerWaalsContact CD1-C 3.46Å; W255-L282 HydrophobicContact CD2-CB 3.88Å; W255-L282 HydrophobicContact CD2-CD1 4.44Å; W255-L282 HydrophobicContact CE3-CB 4.09Å; W255-L282 HydrophobicContact CE3-CD1 3.81Å; W255-L282 HydrophobicContact CE3-CG 4.49Å; W255-L282 HydrophobicContact CG-CB 4.46Å; W255-L282 HydrophobicContact CH2-CB 4.17Å; W255-L282 HydrophobicContact CH2-CD1 4.35Å; W255-L282 HydrophobicContact CH2-CD2 4.26Å; W255-L282 HydrophobicContact CH2-CG 4.49Å; W255-L282 HydrophobicContact CZ2-CB 3.97Å; W255-L282 HydrophobicContact CZ3-CB 4.23Å; W255-L282 HydrophobicContact CZ3-CD1 3.76Å; W255-L282 HydrophobicContact CZ3-CD2 4.45Å; W255-L282 HydrophobicContact CZ3-CG 4.36Å; W255-C285 HydrophobicContact CB-CB 3.99Å
256H97.1Very high94.2Very high6 Ų654 Ų543%0.02829%0.288CS..EExtended strand (participates in β ladder)trans-134.4152.1168.880.595.7000109.7K243 C264 E265 F267 N277 C285K243-H256 HydrophobicContact CB-CB 4.14Å; K243-H256 WeakPolarHBondContact CD-NE2 3.3Å; K243-H256 PolarHBondContact NZ-NE2 3.03Å; H256-C264 CarbonylContact O-C 3.49Å; H256-C264 WeakPolarHBondContact O-CA 3.42Å; H256-E265 PolarHBondContact CD2-O 2.81Å; H256-E265 VanDerWaalsContact CD2-O 3.28Å; H256-E265 PolarHBondContact N-O 3.41Å; H256-E265 PolarHBondContact O-N 3.22Å; H256-F267 HydrophobicContact CB-CD1 3.97Å; H256-F267 HydrophobicContact CB-CE1 3.81Å; H256-F267 AromaticContact CD2-CD1 3.62Å; H256-N277 WeakPolarHBondContact CA-OD1 3.02Å; H256-N277 WeakPolarHBondContact CB-O 3.39Å; H256-C285 VanDerWaalsContact C-SG 3.52Å
257Y96.7Very high94.4Very high6 Ų653.8 Ų53.82%0.02428%0.281CS..EExtended strand (participates in β ladder)trans-77.3135.4167.7-167.1-107.4000110.1C239 A259 E262 N277 C285 C289 V292C239-Y257 HydrophobicContact CB-CD1 3.94Å; C239-Y257 HydrophobicContact CB-CG 4.37Å; C239-Y257 WeakPolarHBondContact O-CD1 3.23Å; Y257-A259 HydrophobicContact CD1-CB 4.28Å; Y257-A259 HydrophobicContact CE1-CB 4.14Å; Y257-E262 WeakPolarHBondContact OH-CA 3.21Å; Y257-N277 PolarHBondContact N-OD1 2.83Å; Y257-N277 PolarHBondContact O-ND2 2.94Å; Y257-C285 PolarHBondContact N-SG 2.96Å; Y257-C289 HydrophobicContact CD1-CB 4.01Å; Y257-C289 HydrophobicContact CD2-CB 3.44Å; Y257-C289 VanDerWaalsContact CD2-CB 3.44Å; Y257-C289 HydrophobicContact CE2-CB 4.04Å; Y257-C289 VanDerWaalsContact CE2-O 3.3Å; Y257-C289 WeakPolarHBondContact CE2-O 3.44Å; Y257-C289 HydrophobicContact CG-CB 3.42Å; Y257-C289 VanDerWaalsContact CG-CB 3.42Å; Y257-V292 HydrophobicContact CE1-CB 4.25Å; Y257-V292 VanDerWaalsContact CE1-O 3.29Å; Y257-V292 WeakPolarHBondContact CE1-O 3.33Å; Y257-V292 PolarHBondContact OH-O 3.22Å
258N93.4Very high94.5Very high42 Ų4257.4 Ų57.423%0.22530%0.299CS..EExtended strand (participates in β ladder)trans-110.798.6173.1-178.4-12.6000108.5A260 S261 E262 R263 E265N258-A260 PolarHBondContact O-N 2.81Å; N258-A260 WeakPolarHBondContact OD1-CB 3.09Å; N258-A260 PolarHBondContact OD1-N 3.46Å; N258-S261 WeakPolarHBondContact CB-OG 3.42Å; N258-S261 VanDerWaalsContact CG-OG 3.3Å; N258-S261 PolarHBondContact ND2-OG 3.04Å; N258-S261 PolarHBondContact O-N 2.98Å; N258-S261 VanDerWaalsContact O-N 3.08Å; N258-S261 PolarHBondContact O-OG 2.99Å; N258-S261 PolarHBondContact OD1-N 3.43Å; N258-E262 WeakPolarHBondContact O-CA 3.38Å; N258-E262 PolarHBondContact O-N 3.15Å; N258-R263 PolarHBondContact N-O 3.15Å; N258-R263 PolarHBondContact O-N 3.29Å; N258-E265 HydrophobicContact CB-CG 4.27Å; N258-E265 PolarHBondContact ND2-OE1 2.91Å; N258-E265 VanDerWaalsContact ND2-OE1 3.1Å; N258-E265 PolarHBondContact ND2-OE2 3.33Å
259A88.2Confident94.6Very high18 Ų1857.3 Ų57.315%0.14930%0.298CS..THydrogen-bonded Turntrans-64.1-10.1-178.600000114.5Y257 V294Y257-A259 HydrophobicContact CD1-CB 4.28Å; Y257-A259 HydrophobicContact CE1-CB 4.14Å; A259-V294 HydrophobicContact CB-CG2 3.89Å; A259-V294 WeakPolarHBondContact O-CG2 3.43Å
260A88Confident94.7Very high96 Ų9649.3 Ų49.379%0.79327%0.268SS*.THydrogen-bonded Turntrans-90.1-25.117400000113.5N258N258-A260 PolarHBondContact O-N 2.81Å; N258-A260 WeakPolarHBondContact OD1-CB 3.09Å; N258-A260 PolarHBondContact OD1-N 3.46Å
261S90.9Very high94.7Very high42 Ų4248.7 Ų48.729%0.29426%0.262SS..THydrogen-bonded Turntrans-103.8-5.7173.4650000113.3N258 R263 E265N258-S261 WeakPolarHBondContact CB-OG 3.42Å; N258-S261 VanDerWaalsContact CG-OG 3.3Å; N258-S261 PolarHBondContact ND2-OG 3.04Å; N258-S261 PolarHBondContact O-N 2.98Å; N258-S261 VanDerWaalsContact O-N 3.08Å; N258-S261 PolarHBondContact O-OG 2.99Å; N258-S261 PolarHBondContact OD1-N 3.43Å; S261-R263 VanDerWaalsContact C-N 3.26Å; S261-R263 WeakPolarHBondContact O-CG 3.14Å; S261-R263 PolarHBondContact O-N 3.04Å; S261-E265 WeakPolarHBondContact CB-OE1 3.42Å; S261-E265 PolarHBondContact OG-OE1 3.11Å
262E91.3Very high94.7Very high104 Ų10444.8 Ų44.849%0.48623%0.234SC..THydrogen-bonded Turntrans55.237.6-175.6-60.8-177.4156.500112.5Y257 N258 S293Y257-E262 WeakPolarHBondContact OH-CA 3.21Å; N258-E262 WeakPolarHBondContact O-CA 3.38Å; N258-E262 PolarHBondContact O-N 3.15Å; E262-S293 VanDerWaalsContact OE1-CB 3.25Å; E262-S293 WeakPolarHBondContact OE1-CB 3.38Å
263R93.2Very high94.5Very high177 Ų17746.1 Ų46.167%0.66824%0.239SC*.EExtended strand (participates in β ladder)trans-141.4152.7-172.7-70.7171-166.2-145.2-3.2112.8N258 S261N258-R263 PolarHBondContact N-O 3.15Å; N258-R263 PolarHBondContact O-N 3.29Å; S261-R263 VanDerWaalsContact C-N 3.26Å; S261-R263 WeakPolarHBondContact O-CG 3.14Å; S261-R263 PolarHBondContact O-N 3.04Å
264C96.9Very high94.4Very high23 Ų2345 Ų4516%0.15523%0.228CC..EExtended strand (participates in β ladder)trans-75.5126.5163-69.40000110.5W255 H256 L282 C285 A286W255-C264 HydrophobicContact CE3-CB 4.1Å; H256-C264 CarbonylContact O-C 3.49Å; H256-C264 WeakPolarHBondContact O-CA 3.42Å; C264-L282 HydrophobicContact CB-CD1 3.48Å; C264-L282 VanDerWaalsContact CB-CD1 3.48Å; C264-C285 HydrophobicContact CB-CB 3.85Å; C264-C285 WeakPolarHBondContact CB-SG 3.27Å; C264-C285 WeakPolarHBondContact SG-CB 3.3Å; C264-C285 CovalentContact SG-SG 2.03Å; C264-C285 PolarHBondContact SG-SG 3.23Å; C264-A286 PolarHBondContact SG-N 2.87Å; C264-A286 VanDerWaalsContact SG-N 3.39Å
265E97.3Very high94.2Very high60 Ų6045.5 Ų45.528%0.2823%0.231SC..EExtended strand (participates in β ladder)trans-125143.3-178.4-69.5175.3-174.500110.1W255 H256 N258 S261W255-E265 WeakPolarHBondContact CA-O 3.25Å; H256-E265 PolarHBondContact CD2-O 2.81Å; H256-E265 VanDerWaalsContact CD2-O 3.28Å; H256-E265 PolarHBondContact N-O 3.41Å; H256-E265 PolarHBondContact O-N 3.22Å; N258-E265 HydrophobicContact CB-CG 4.27Å; N258-E265 PolarHBondContact ND2-OE1 2.91Å; N258-E265 VanDerWaalsContact ND2-OE1 3.1Å; N258-E265 PolarHBondContact ND2-OE2 3.33Å; S261-E265 WeakPolarHBondContact CB-OE1 3.42Å; S261-E265 PolarHBondContact OG-OE1 3.11Å
266E97.6Very high94Very high115 Ų11546.6 Ų46.654%0.53724%0.241SC..EExtended strand (participates in β ladder)trans-77.5144175.5-168-179.5171.400111P253 R254 W255P253-E266 VanDerWaalsContact CB-OE1 3.29Å; P253-E266 WeakPolarHBondContact CB-OE1 3.31Å; R254-E266 CarbonylContact O-C 3.01Å; R254-E266 WeakPolarHBondContact O-CA 3.41Å; W255-E266 HydrophobicContact CH2-CB 4.4Å; W255-E266 HydrophobicContact CZ2-CB 4.39Å; W255-E266 HydrophobicContact CZ3-CB 4.45Å
267F97.2Very high94Very high15 Ų1546.3 Ų46.37%0.06624%0.24CC..EExtended strand (participates in β ladder)trans-147.4162.6171.680.5-71.5000111.5K243 K244 R254 H256 F269K243-F267 HydrophobicContact CB-CD1 4.37Å; K243-F267 HydrophobicContact CB-CD2 4.03Å; K243-F267 HydrophobicContact CB-CE1 4.47Å; K243-F267 HydrophobicContact CB-CE2 4.14Å; K243-F267 HydrophobicContact CB-CG 4.15Å; K243-F267 HydrophobicContact CB-CZ 4.35Å; K243-F267 HydrophobicContact CD-CB 3.66Å; K243-F267 HydrophobicContact CD-CD2 4.06Å; K243-F267 HydrophobicContact CD-CG 3.91Å; K244-F267 WeakPolarHBondContact O-CE2 3.39Å; R254-F267 HydrophobicContact CB-CD1 4.06Å; R254-F267 HydrophobicContact CB-CE1 3.55Å; R254-F267 HydrophobicContact CB-CZ 3.99Å; R254-F267 PolarHBondContact N-O 3.16Å; R254-F267 VanDerWaalsContact O-CD1 3.32Å; R254-F267 WeakPolarHBondContact O-CD1 3.43Å; R254-F267 PolarHBondContact O-N 2.92Å; H256-F267 HydrophobicContact CB-CD1 3.97Å; H256-F267 HydrophobicContact CB-CE1 3.81Å; H256-F267 AromaticContact CD2-CD1 3.62Å; F267-F269 HydrophobicContact CE2-CB 4.05Å; F267-F269 HydrophobicContact CZ-CB 4.25Å
268L97.3Very high93.9Very high101 Ų10146.6 Ų46.653%0.52924%0.242SC..EExtended strand (participates in β ladder)trans-89.7116.1172.9-62.5177.4000109.9
269F96.9Very high94.1Very high0 Ų044.8 Ų44.80%023%0.232CC..EExtended strand (participates in β ladder)trans-86.5141.3169.8174.7-124.9000110.5V245 F252 R254 F267 C272 E274 N278V245-F269 WeakPolarHBondContact O-CD2 3.44Å; F252-F269 WeakPolarHBondContact CD2-O 3.36Å; F252-F269 PolarHBondContact N-O 2.99Å; F252-F269 PolarHBondContact O-N 3.23Å; R254-F269 HydrophobicContact CB-CB 4.21Å; R254-F269 HydrophobicContact CG-CB 3.52Å; R254-F269 HydrophobicContact CG-CD1 4.28Å; R254-F269 HydrophobicContact CG-CG 4.23Å; F267-F269 HydrophobicContact CE2-CB 4.05Å; F267-F269 HydrophobicContact CZ-CB 4.25Å; F269-C272 WeakPolarHBondContact CE2-O 3.45Å; F269-E274 HydrophobicContact CE2-CB 3.83Å; F269-E274 HydrophobicContact CZ-CB 3.69Å; F269-N278 WeakPolarHBondContact CD2-ND2 3.32Å
270G94.4Very high94.3Very high0 Ų046 Ų460%024%0.236CC..  trans-78.3-15-176.400000115.3V245 C248 G250 F355V245-G270 VanDerWaalsContact O-CA 3.3Å; V245-G270 WeakPolarHBondContact O-CA 3.36Å; V245-G270 PolarHBondContact O-N 3.37Å; C248-G270 CarbonylContact C-O 3.58Å; C248-G270 WeakPolarHBondContact CB-O 3.49Å; C248-G270 WeakPolarHBondContact O-CA 3.03Å; G250-G270 VanDerWaalsContact CA-O 3.31Å; G250-G270 WeakPolarHBondContact CA-O 3.37Å; G250-G270 PolarHBondContact N-O 2.82Å; G270-F355 WeakPolarHBondContact O-CE1 3.37Å
271G92.4Very high94.6Very high0 Ų042.1 Ų42.10%020%0.203CC..SBendtrans103.9-0.9174.600000116.4
272C93Very high94.7Very high0 Ų044.2 Ų44.20%021%0.211CC..SBendtrans-153.9157.6174.4740000111.7F57 C248 F269 L351F57-C272 HydrophobicContact CB-CB 4.47Å; F57-C272 HydrophobicContact CD1-CB 4.43Å; C248-C272 HydrophobicContact CB-CB 4.01Å; C248-C272 WeakPolarHBondContact CB-SG 3.36Å; C248-C272 WeakPolarHBondContact SG-CB 3.49Å; C248-C272 CovalentContact SG-SG 2.03Å; C248-C272 PolarHBondContact SG-SG 2.96Å; F269-C272 WeakPolarHBondContact CE2-O 3.45Å; C272-L351 HydrophobicContact CB-CD2 4.23Å; C272-L351 WeakPolarHBondContact SG-CD2 3.4Å
273R92.3Very high94.7Very high33 Ų3344.7 Ų44.713%0.12521%0.213CC..SBendtrans55.650.3179.5-50.5-57.2-177.61699.4113.1K244 P247 E332 C333 L351K244-R273 WeakPolarHBondContact CD-O 3.29Å; K244-R273 WeakPolarHBondContact CE-O 3.41Å; P247-R273 HydrophobicContact CG-CB 4.5Å; P247-R273 HydrophobicContact CG-CG 4.17Å; R273-E332 IonicContact CZ-OE1 3.64Å; R273-E332 IonicContact CZ-OE2 3.57Å; R273-E332 IonicContact NE-OE1 3.89Å; R273-E332 PolarHBondContact NE-OE1 2.78Å; R273-E332 IonicContact NE-OE2 2.91Å; R273-E332 IonicContact NH1-OE1 3.51Å; R273-E332 PolarHBondContact NH1-OE1 2.9Å; R273-E332 IonicContact NH1-OE2 3.77Å; R273-E332 PolarHBondContact NH1-OE2 2.87Å; R273-E332 IonicContact NH2-OE1 2.68Å; R273-E332 PolarHBondContact NH2-OE1 2.94Å; R273-E332 IonicContact NH2-OE2 2.69Å; R273-E332 PolarHBondContact NH2-OE2 3.09Å; R273-C333 HydrophobicContact CG-CB 4.48Å; R273-L351 HydrophobicContact CG-CD2 3.52Å; R273-L351 VanDerWaalsContact NE-CD2 3.35Å
274E93.2Very high94.7Very high39 Ų3937.8 Ų37.818%0.18219%0.188CC..  trans-59.4152166.469.9-72.917900112.2T56 K78 F269 N278T56-E274 WeakPolarHBondContact CG2-OE2 3.03Å; T56-E274 PolarHBondContact OG1-OE1 2.93Å; T56-E274 PolarHBondContact OG1-OE2 3.29Å; K78-E274 IonicContact NZ-OE1 2.67Å; F269-E274 HydrophobicContact CE2-CB 3.83Å; F269-E274 HydrophobicContact CZ-CB 3.69Å; E274-N278 HydrophobicContact CB-CB 4.36Å
275N93.4Very high94.6Very high16 Ų1636.7 Ų36.79%0.08618%0.181CC..  trans-99.3176.6157.163.9-1.2000109.8V241 P242 K244 N277 N278V241-N275 WeakPolarHBondContact CG2-ND2 3.31Å; P242-N275 PolarHBondContact O-ND2 3.41Å; K244-N275 HydrophobicContact CB-CB 4.22Å; K244-N275 HydrophobicContact CD-CB 4.26Å; N275-N277 VanDerWaalsContact C-N 3.25Å; N275-N277 PolarHBondContact O-N 2.65Å; N275-N278 WeakPolarHBondContact O-CB 3.47Å
276L93.8Very high94.4Very high85 Ų8535 Ų3545%0.44518%0.177SC..SBendtrans-73-14-173.8-61.3177.1000114.1N237 H238 N278 Y279N237-L276 HydrophobicContact CB-CD1 4.18Å; N237-L276 WeakPolarHBondContact O-CB 3.43Å; H238-L276 PolarHBondContact ND1-O 2.86Å; L276-N278 PolarHBondContact O-N 3.43Å; L276-N278 VanDerWaalsContact O-N 3.14Å; L276-Y279 PolarHBondContact O-OH 3.09Å
277N95.8Very high94.2Very high0 Ų030 Ų300%015%0.154CC..SBendtrans-86.357.4171.7-167.44.7000111.4H238 C239 V241 H256 Y257 N275H238-N277 WeakPolarHBondContact O-CA 3.23Å; H238-N277 WeakPolarHBondContact O-CB 3.24Å; H238-N277 PolarHBondContact O-OD1 3.14Å; C239-N277 PolarHBondContact O-ND2 3.19Å; V241-N277 HydrophobicContact CG2-CB 3.58Å; V241-N277 PolarHBondContact O-ND2 2.61Å; H256-N277 WeakPolarHBondContact CA-OD1 3.02Å; H256-N277 WeakPolarHBondContact CB-O 3.39Å; Y257-N277 PolarHBondContact N-OD1 2.83Å; Y257-N277 PolarHBondContact O-ND2 2.94Å; N275-N277 VanDerWaalsContact C-N 3.25Å; N275-N277 PolarHBondContact O-N 2.65Å
278N96.2Very high94.1Very high12 Ų1229.3 Ų29.36%0.06415%0.151CC..  trans-147.2108-177.1-174.3-28000110.2R254 F269 E274 N275 L276R254-N278 WeakPolarHBondContact CB-OD1 3.08Å; R254-N278 VanDerWaalsContact CD-OD1 3.31Å; R254-N278 WeakPolarHBondContact CD-OD1 3.48Å; R254-N278 VanDerWaalsContact CG-OD1 3.23Å; R254-N278 WeakPolarHBondContact CG-OD1 3.29Å; R254-N278 PolarHBondContact NH1-OD1 3.24Å; F269-N278 WeakPolarHBondContact CD2-ND2 3.32Å; E274-N278 HydrophobicContact CB-CB 4.36Å; N275-N278 WeakPolarHBondContact O-CB 3.47Å; L276-N278 PolarHBondContact O-N 3.43Å; L276-N278 VanDerWaalsContact O-N 3.14Å
279Y96.3Very high93.9Very high4 Ų424.5 Ų24.52%0.01613%0.126CC..BIsolated β-bridgetrans-121144.9-171.8-55.8-82000110.8H238 W255 L276 E284 C285 A288H238-Y279 PolarHBondContact ND1-OH 2.83Å; H238-Y279 PolarHBondContact O-OH 3.37Å; W255-Y279 PolarHBondContact N-O 3.45Å; W255-Y279 PolarHBondContact O-N 2.92Å; L276-Y279 PolarHBondContact O-OH 3.09Å; Y279-E284 HydrophobicContact CD1-CB 4.11Å; Y279-E284 HydrophobicContact CG-CB 4.5Å; Y279-C285 HydrophobicContact CD2-CB 3.6Å; Y279-C285 HydrophobicContact CE2-CB 4.32Å; Y279-C285 HydrophobicContact CG-CB 3.84Å; Y279-A288 HydrophobicContact CD1-CB 4.45Å; Y279-A288 HydrophobicContact CE1-CB 3.54Å; Y279-A288 WeakPolarHBondContact OH-CB 3.36Å
280L93.8Very high93.5Very high45 Ų4529.9 Ų29.924%0.23616%0.155CC..SBendtrans-71.9-33.6176.1-73.6179.1000112.6K52 Y53 Y103K52-L280 WeakPolarHBondContact O-CD2 3.28Å; Y53-L280 VanDerWaalsContact O-CD1 3.23Å; Y53-L280 WeakPolarHBondContact O-CD1 3.46Å; Y103-L280 HydrophobicContact CD1-CD1 3.37Å; Y103-L280 HydrophobicContact CD1-CG 4.18Å; Y103-L280 HydrophobicContact CD2-CD1 4.31Å; Y103-L280 HydrophobicContact CE1-CB 4.23Å; Y103-L280 HydrophobicContact CE1-CD1 3.3Å; Y103-L280 HydrophobicContact CE1-CG 3.64Å; Y103-L280 HydrophobicContact CE2-CD1 4.28Å; Y103-L280 HydrophobicContact CE2-CG 4.15Å; Y103-L280 HydrophobicContact CG-CD1 3.89Å; Y103-L280 PolarHBondContact OH-N 3.17Å
281S92.7Very high93Very high14 Ų1433 Ų3310%0.09819%0.187CC..SBendtrans-128.2153.9-175.870.30000113.3W255 Q283 E284 C285W255-S281 VanDerWaalsContact CD1-C 3.46Å; S281-Q283 PolarHBondContact O-N 2.94Å; S281-E284 WeakPolarHBondContact CB-OE1 3.3Å; S281-E284 PolarHBondContact N-OE1 2.86Å; S281-E284 PolarHBondContact O-N 3.4Å; S281-E284 VanDerWaalsContact OG-CD 3.3Å; S281-E284 VanDerWaalsContact OG-CG 3.3Å; S281-E284 WeakPolarHBondContact OG-CG 3.49Å; S281-E284 PolarHBondContact OG-N 3.35Å; S281-E284 PolarHBondContact OG-OE1 3.3Å; S281-C285 PolarHBondContact O-N 2.94Å; S281-C285 VanDerWaalsContact O-N 3.16Å
282L93.5Very high92.6Very high86 Ų8633.4 Ų33.445%0.4519%0.189SC..Hα-helixtrans-54.5-40.8171.2171.658.1000111.5W255 C264 E284 C285 A286W255-L282 HydrophobicContact CD2-CB 3.88Å; W255-L282 HydrophobicContact CD2-CD1 4.44Å; W255-L282 HydrophobicContact CE3-CB 4.09Å; W255-L282 HydrophobicContact CE3-CD1 3.81Å; W255-L282 HydrophobicContact CE3-CG 4.49Å; W255-L282 HydrophobicContact CG-CB 4.46Å; W255-L282 HydrophobicContact CH2-CB 4.17Å; W255-L282 HydrophobicContact CH2-CD1 4.35Å; W255-L282 HydrophobicContact CH2-CD2 4.26Å; W255-L282 HydrophobicContact CH2-CG 4.49Å; W255-L282 HydrophobicContact CZ2-CB 3.97Å; W255-L282 HydrophobicContact CZ3-CB 4.23Å; W255-L282 HydrophobicContact CZ3-CD1 3.76Å; W255-L282 HydrophobicContact CZ3-CD2 4.45Å; W255-L282 HydrophobicContact CZ3-CG 4.36Å; C264-L282 HydrophobicContact CB-CD1 3.48Å; C264-L282 VanDerWaalsContact CB-CD1 3.48Å; L282-E284 PolarHBondContact O-N 2.91Å; L282-C285 PolarHBondContact O-N 2.93Å; L282-A286 WeakPolarHBondContact O-CB 3.4Å; L282-A286 PolarHBondContact O-N 2.93Å
283Q90.9Very high91.9Very high113 Ų11335 Ų3553%0.52820%0.2SC..Hα-helixtrans-64.5-40.8-179.5-168.768.554.500111.8S281 A286 N287S281-Q283 PolarHBondContact O-N 2.94Å; Q283-A286 PolarHBondContact O-N 3.35Å; Q283-N287 PolarHBondContact NE2-OD1 3.28Å; Q283-N287 WeakPolarHBondContact O-CB 3.46Å; Q283-N287 PolarHBondContact O-N 3.49Å; Q283-N287 PolarHBondContact O-OD1 3.25Å
284E93.5Very high90.6Very high32 Ų3238.1 Ų38.115%0.1522%0.222CC..Hα-helixtrans-66-40.5176.6-73.4162-106.300112.5Y103 K104 Y279 S281 L282 A288Y103-E284 WeakPolarHBondContact CE1-OE2 3.25Å; Y103-E284 PolarHBondContact OH-OE2 2.89Å; K104-E284 IonicContact NZ-OE2 3.46Å; K104-E284 PolarHBondContact NZ-OE2 2.87Å; Y279-E284 HydrophobicContact CD1-CB 4.11Å; Y279-E284 HydrophobicContact CG-CB 4.5Å; S281-E284 WeakPolarHBondContact CB-OE1 3.3Å; S281-E284 PolarHBondContact N-OE1 2.86Å; S281-E284 PolarHBondContact O-N 3.4Å; S281-E284 VanDerWaalsContact OG-CD 3.3Å; S281-E284 VanDerWaalsContact OG-CG 3.3Å; S281-E284 WeakPolarHBondContact OG-CG 3.49Å; S281-E284 PolarHBondContact OG-N 3.35Å; S281-E284 PolarHBondContact OG-OE1 3.3Å; L282-E284 PolarHBondContact O-N 2.91Å; E284-A288 WeakPolarHBondContact O-CB 3.36Å; E284-A288 PolarHBondContact O-N 3.42Å
285C95.7Very high88.8Confident0 Ų042.4 Ų42.40%025%0.246CC..Hα-helixtrans-64.4-43174.4174.90000111.6W255 H256 Y257 C264 Y279 S281 L282 A288 C289W255-C285 HydrophobicContact CB-CB 3.99Å; H256-C285 VanDerWaalsContact C-SG 3.52Å; Y257-C285 PolarHBondContact N-SG 2.96Å; C264-C285 HydrophobicContact CB-CB 3.85Å; C264-C285 WeakPolarHBondContact CB-SG 3.27Å; C264-C285 WeakPolarHBondContact SG-CB 3.3Å; C264-C285 CovalentContact SG-SG 2.03Å; C264-C285 PolarHBondContact SG-SG 3.23Å; Y279-C285 HydrophobicContact CD2-CB 3.6Å; Y279-C285 HydrophobicContact CE2-CB 4.32Å; Y279-C285 HydrophobicContact CG-CB 3.84Å; S281-C285 PolarHBondContact O-N 2.94Å; S281-C285 VanDerWaalsContact O-N 3.16Å; L282-C285 PolarHBondContact O-N 2.93Å; C285-A288 PolarHBondContact O-N 3.04Å; C285-C289 WeakPolarHBondContact O-CB 3.3Å; C285-C289 PolarHBondContact O-N 2.99Å
286A93.6Very high86.8Confident25 Ų2548.7 Ų48.721%0.20727%0.274CS..Hα-helixtrans-62.5-53.6179.200000110.8C264 L282 Q283 A288 C289 D290C264-A286 PolarHBondContact SG-N 2.87Å; C264-A286 VanDerWaalsContact SG-N 3.39Å; L282-A286 WeakPolarHBondContact O-CB 3.4Å; L282-A286 PolarHBondContact O-N 2.93Å; Q283-A286 PolarHBondContact O-N 3.35Å; A286-A288 PolarHBondContact O-N 3.04Å; A286-C289 PolarHBondContact O-N 3.14Å; A286-C289 VanDerWaalsContact O-N 3.15Å; A286-D290 VanDerWaalsContact O-CB 3.22Å; A286-D290 WeakPolarHBondContact O-CB 3.33Å; A286-D290 PolarHBondContact O-N 3.04Å
287N92.5Very high84.6Confident11 Ų1156.2 Ų56.26%0.05930%0.297CS..Hα-helixtrans-55.1-42.1176.3-67.624.7000111.8V153 Q154 E157 Q283 C289V153-N287 CarbonylContact C-O 3.57Å; V153-N287 VanDerWaalsContact CA-O 3.25Å; V153-N287 WeakPolarHBondContact CA-O 3.41Å; V153-N287 HydrophobicContact CG1-CB 4.24Å; Q154-N287 PolarHBondContact N-O 2.79Å; E157-N287 WeakPolarHBondContact OE2-CA 3.5Å; Q283-N287 PolarHBondContact NE2-OD1 3.28Å; Q283-N287 WeakPolarHBondContact O-CB 3.46Å; Q283-N287 PolarHBondContact O-N 3.49Å; Q283-N287 PolarHBondContact O-OD1 3.25Å; N287-C289 PolarHBondContact O-N 2.91Å
288A94.4Very high82.3Confident0 Ų059.7 Ų59.70%033%0.332CS..Hα-helixtrans-72.1-25.4-177.400000113.8V152 Q154 L230 C239 Y279 E284 C285 A286V152-A288 HydrophobicContact CB-CB 4.33Å; V152-A288 HydrophobicContact CG1-CB 4.1Å; V152-A288 WeakPolarHBondContact O-CA 3.17Å; V152-A288 PolarHBondContact O-N 3.27Å; Q154-A288 WeakPolarHBondContact CG-O 3.42Å; Q154-A288 PolarHBondContact NE2-O 2.93Å; L230-A288 VanDerWaalsContact CD1-O 3.29Å; L230-A288 WeakPolarHBondContact CD1-O 3.3Å; C239-A288 PolarHBondContact SG-O 2.82Å; Y279-A288 HydrophobicContact CD1-CB 4.45Å; Y279-A288 HydrophobicContact CE1-CB 3.54Å; Y279-A288 WeakPolarHBondContact OH-CB 3.36Å; E284-A288 WeakPolarHBondContact O-CB 3.36Å; E284-A288 PolarHBondContact O-N 3.42Å; C285-A288 PolarHBondContact O-N 3.04Å; A286-A288 PolarHBondContact O-N 3.04Å
289C94.1Very high80Confident0 Ų068 Ų680%036%0.363CS..Hα-helixtrans-142.8-2.2-164.2-61.30000116.9H238 C239 Y257 C285 A286 N287 V292H238-C289 PolarHBondContact O-SG 2.03Å; C239-C289 VanDerWaalsContact CA-SG 3.51Å; C239-C289 HydrophobicContact CB-CB 3.72Å; C239-C289 WeakPolarHBondContact CB-SG 3Å; C239-C289 WeakPolarHBondContact SG-CA 3.37Å; C239-C289 WeakPolarHBondContact SG-CB 3.31Å; C239-C289 CovalentContact SG-SG 2.03Å; C239-C289 PolarHBondContact SG-SG 2.02Å; Y257-C289 HydrophobicContact CD1-CB 4.01Å; Y257-C289 HydrophobicContact CD2-CB 3.44Å; Y257-C289 VanDerWaalsContact CD2-CB 3.44Å; Y257-C289 HydrophobicContact CE2-CB 4.04Å; Y257-C289 VanDerWaalsContact CE2-O 3.3Å; Y257-C289 WeakPolarHBondContact CE2-O 3.44Å; Y257-C289 HydrophobicContact CG-CB 3.42Å; Y257-C289 VanDerWaalsContact CG-CB 3.42Å; C285-C289 WeakPolarHBondContact O-CB 3.3Å; C285-C289 PolarHBondContact O-N 2.99Å; A286-C289 PolarHBondContact O-N 3.14Å; A286-C289 VanDerWaalsContact O-N 3.15Å; N287-C289 PolarHBondContact O-N 2.91Å; C289-V292 VanDerWaalsContact O-CB 3.3Å; C289-V292 WeakPolarHBondContact O-CB 3.48Å; C289-V292 VanDerWaalsContact O-CG2 3.31Å; C289-V292 WeakPolarHBondContact O-CG2 3Å; C289-V292 PolarHBondContact O-N 3.02Å; C289-V292 VanDerWaalsContact O-N 3.17Å
290D88.7Confident77.2Confident113 Ų11375 Ų7560%0.60441%0.406SS*.THydrogen-bonded Turntrans-62.9143.1178.2-165.718.3000111.2A286 V292A286-D290 VanDerWaalsContact O-CB 3.22Å; A286-D290 WeakPolarHBondContact O-CB 3.33Å; A286-D290 PolarHBondContact O-N 3.04Å; D290-V292 PolarHBondContact O-N 3.49Å
291G83.1Confident75.1Confident65 Ų6575.1 Ų75.167%0.6742%0.418SS*.THydrogen-bonded Turntrans70.6-2-172.100000116.6S293G291-S293 PolarHBondContact O-N 3.08Å; G291-S293 VanDerWaalsContact O-N 3.1Å
292V85.3Confident73Confident9 Ų980.6 Ų80.66%0.05545%0.453CS..  trans-77.794.2178.2-178.30000111.2Q154 C239 M240 Y257 C289 D290Q154-V292 HydrophobicContact CG-CG2 3.8Å; Q154-V292 VanDerWaalsContact NE2-CG2 3.34Å; C239-V292 HydrophobicContact CB-CB 4.5Å; C239-V292 HydrophobicContact CB-CG1 4.15Å; M240-V292 HydrophobicContact CE-CG1 3.54Å; M240-V292 HydrophobicContact CG-CG1 4.41Å; Y257-V292 HydrophobicContact CE1-CB 4.25Å; Y257-V292 VanDerWaalsContact CE1-O 3.29Å; Y257-V292 WeakPolarHBondContact CE1-O 3.33Å; Y257-V292 PolarHBondContact OH-O 3.22Å; C289-V292 VanDerWaalsContact O-CB 3.3Å; C289-V292 WeakPolarHBondContact O-CB 3.48Å; C289-V292 VanDerWaalsContact O-CG2 3.31Å; C289-V292 WeakPolarHBondContact O-CG2 3Å; C289-V292 PolarHBondContact O-N 3.02Å; C289-V292 VanDerWaalsContact O-N 3.17Å; D290-V292 PolarHBondContact O-N 3.49Å
293S76.6Confident71.2Confident32 Ų3281.4 Ų81.422%0.22446%0.457CS..  trans-91.6153.9172.271.80000112.6E262 G291 I295E262-S293 VanDerWaalsContact OE1-CB 3.25Å; E262-S293 WeakPolarHBondContact OE1-CB 3.38Å; G291-S293 PolarHBondContact O-N 3.08Å; G291-S293 VanDerWaalsContact O-N 3.1Å; S293-I295 PolarHBondContact O-N 2.85Å; S293-I295 VanDerWaalsContact O-N 3.09Å
294V65.2Low69.7Low99 Ų9981.4 Ų81.460%0.647%0.467SS*.SBendtrans-62.5-14.1172.3-1740000111.9A259 H296A259-V294 HydrophobicContact CB-CG2 3.89Å; A259-V294 WeakPolarHBondContact O-CG2 3.43Å; V294-H296 VanDerWaalsContact C-N 3.29Å; V294-H296 PolarHBondContact O-N 2.91Å; V294-H296 VanDerWaalsContact O-N 3.14Å
295I55.2Low68.4Low130 Ų13083 Ų8367%0.66749%0.486SS*.  trans-91.346.2-171.5-38.8-176.2000112.2S293 R297S293-I295 PolarHBondContact O-N 2.85Å; S293-I295 VanDerWaalsContact O-N 3.09Å; I295-R297 PolarHBondContact O-N 2.94Å
296H51.6Low67.4Low147 Ų14786.7 Ų86.768%0.68151%0.51SS*.  trans-76.4105.9163.2-98.8-70.3000111V294 G298V294-H296 VanDerWaalsContact C-N 3.29Å; V294-H296 PolarHBondContact O-N 2.91Å; V294-H296 VanDerWaalsContact O-N 3.14Å; H296-G298 PolarHBondContact O-N 3.49Å
297R47.4Very low66.6Low244 Ų24495 Ų9592%0.92154%0.536SS*.THydrogen-bonded Turntrans-60.3111.2-174.7-57.3173.6-180-174.2-1.1111.9I295I295-R297 PolarHBondContact O-N 2.94Å
298G47.8Very low66.4Low72 Ų7295.9 Ų95.974%0.74254%0.54SS*.THydrogen-bonded Turntrans162.5-34.5163.800000117.4H296 T300H296-G298 PolarHBondContact O-N 3.49Å; G298-T300 PolarHBondContact O-N 2.88Å
299R47.4Very low66.2Low188 Ų18899.7 Ų99.771%0.70956%0.562SS**  trans-94.287.2-179.8-78.7-180171.4164.1-4.9111.5E236 G301E236-R299 IonicContact OE1-NH1 3.51Å; R299-G301 VanDerWaalsContact C-N 3.3Å; R299-G301 PolarHBondContact O-N 2.97Å; R299-G301 VanDerWaalsContact O-N 3.08Å
300T38.6Very low66Low151 Ų151103.2 Ų103.293%0.92659%0.586SS**  trans-78.480.8165.650.90000110.3G298G298-T300 PolarHBondContact O-N 2.88Å
301G49.8Very low65.9Low47 Ų47101.7 Ų101.749%0.48560%0.597SS.*SBendtrans176.8153.2173.800000110.2R299 L303R299-G301 VanDerWaalsContact C-N 3.3Å; R299-G301 PolarHBondContact O-N 2.97Å; R299-G301 VanDerWaalsContact O-N 3.08Å; G301-L303 PolarHBondContact O-N 3.13Å
302P49.2Very low66.1Low129 Ų129102.1 Ų102.184%0.83859%0.587SS**PPolyproline II helixtrans-55133.7167.3-19.932000108.9
303L55.1Low66.2Low102 Ų102107.8 Ų107.853%0.53462%0.624SS.*PPolyproline II helixtrans-54.2133.1164.4-75.7163.4000107.3G301 A305G301-L303 PolarHBondContact O-N 3.13Å; L303-A305 PolarHBondContact O-N 3.17Å
304P59Low66.6Low114 Ų114108.5 Ų108.574%0.7463%0.628SS**PPolyproline II helixtrans-58.2130.7173.325.7-32.4000107.6
305A66.2Low67.5Low65 Ų65105.7 Ų105.754%0.53762%0.62SS.*PPolyproline II helixtrans-51.4136177.500000109.4L303 R307L303-A305 PolarHBondContact O-N 3.17Å; A305-R307 PolarHBondContact O-N 3.49Å
306P74.3Confident68.6Low78 Ų78103.6 Ų103.651%0.50662%0.616SS.*PPolyproline II helixtrans-58.7140.1-179.825.4-33.8000109.8L331P306-L331 HydrophobicContact CB-CD1 3.74Å; P306-L331 HydrophobicContact CG-CD1 4.02Å; P306-L331 HydrophobicContact CG-CD2 4.23Å
307R78.1Confident69.8Low199 Ų19998.7 Ų98.775%0.75161%0.605SS**  trans-141.8154.1-175-74.6176.2-175.5-165-2109.9A305A305-R307 PolarHBondContact O-N 3.49Å
308E87.1Confident71.7Confident30 Ų3090.6 Ų90.614%0.1458%0.578CS.*  trans-56.7144.8171.571.4-172165.300112.2C321 N323 C325 C326 C339 S340E308-C321 PolarHBondContact OE2-SG 3.14Å; E308-N323 PolarHBondContact OE2-ND2 3.1Å; E308-C325 HydrophobicContact CB-CB 3.84Å; E308-C325 HydrophobicContact CG-CB 3.88Å; E308-C325 WeakPolarHBondContact OE2-CB 3.3Å; E308-C326 CarbonylContact C-O 3.4Å; E308-C326 WeakPolarHBondContact CA-O 3.23Å; E308-C339 WeakPolarHBondContact OE2-CA 3.46Å; E308-S340 VanDerWaalsContact CD-N 3.34Å; E308-S340 WeakPolarHBondContact OE1-CB 3.43Å; E308-S340 PolarHBondContact OE1-N 3.23Å; E308-S340 PolarHBondContact OE1-OG 2.85Å; E308-S340 PolarHBondContact OE2-N 2.97Å
309V89.7Confident73.6Confident79 Ų7988.7 Ų88.748%0.47955%0.549SS..BIsolated β-bridgetrans-113.2112.5175.6-177.70000108.5V312 C326V309-V312 HydrophobicContact CG1-CG2 4.07Å; V309-C326 PolarHBondContact N-O 3.34Å; V309-C326 PolarHBondContact O-N 2.9Å
310C91.3Very high75.7Confident74 Ų7483 Ų8350%0.554%0.539SS..  trans-95.9154.6-176.2-52.90000112.5C325C310-C325 HydrophobicContact CB-CB 3.97Å; C310-C325 WeakPolarHBondContact CB-SG 3.04Å; C310-C325 WeakPolarHBondContact SG-CB 3.1Å; C310-C325 CovalentContact SG-SG 2.03Å; C310-C325 PolarHBondContact SG-SG 3.28Å
311G85.5Confident78.1Confident81 Ų8175.9 Ų75.984%0.83550%0.495SS*.SBendtrans85.68.3171.700000115.6
312V87.6Confident80.1Confident75 Ų7579.2 Ų79.246%0.45551%0.506SS..SBendtrans-123.5149.1170.3-65.70000109.4V309 C326V309-V312 HydrophobicContact CG1-CG2 4.07Å; V312-C326 PolarHBondContact O-SG 2.85Å; V312-C326 VanDerWaalsContact O-SG 3.35Å
313P86.9Confident82Confident127 Ų12776.4 Ų76.483%0.82548%0.484SS*.PPolyproline II helixtrans-70.1135.7171.730-33.8000110.1
314C86.6Confident83.6Confident47 Ų4773.5 Ų73.532%0.31848%0.479SS..PPolyproline II helixtrans-71138.9-176.6-48.80000112Q318 C326C314-Q318 HydrophobicContact CB-CB 4.06Å; C314-C326 WeakPolarHBondContact CA-SG 3.45Å; C314-C326 HydrophobicContact CB-CB 3.82Å; C314-C326 WeakPolarHBondContact CB-SG 3.21Å; C314-C326 PolarHBondContact N-SG 3.39Å; C314-C326 WeakPolarHBondContact SG-CA 3.36Å; C314-C326 WeakPolarHBondContact SG-CB 3.32Å; C314-C326 CovalentContact SG-SG 2.04Å; C314-C326 PolarHBondContact SG-SG 3.39Å
315G83.8Confident85.2Confident41 Ų4168.5 Ų68.542%0.42345%0.446SS..PPolyproline II helixtrans-75.9168.7173.600000113.1G317 Q318G315-G317 PolarHBondContact O-N 3.34Å; G315-G317 VanDerWaalsContact O-N 3.13Å; G315-Q318 PolarHBondContact O-N 3.47Å
316S77Confident86.5Confident85 Ų8565.5 Ų65.559%0.59442%0.421SS*.THydrogen-bonded Turntrans-61.1-21.418050.40000115R329S316-R329 PolarHBondContact O-NH1 3.46Å
317G77.6Confident87.3Confident44 Ų4462 Ų6245%0.45440%0.398SS..THydrogen-bonded Turntrans-93.25.4174.500000115.1G315 R329G315-G317 PolarHBondContact O-N 3.34Å; G315-G317 VanDerWaalsContact O-N 3.13Å; G317-R329 WeakPolarHBondContact O-CB 3.44Å; G317-R329 PolarHBondContact O-N 3.17Å
318Q86.8Confident87.8Confident74 Ų7455.2 Ų55.235%0.34638%0.377SS..EExtended strand (participates in β ladder)trans-112.5148.4-176.5-71.7175.3-35.400111.9C314 G315 C326 L327C314-Q318 HydrophobicContact CB-CB 4.06Å; G315-Q318 PolarHBondContact O-N 3.47Å; Q318-C326 HydrophobicContact CB-CB 4.42Å; Q318-L327 CarbonylContact C-O 3.54Å; Q318-L327 VanDerWaalsContact CA-O 3.24Å; Q318-L327 WeakPolarHBondContact CA-O 3.38Å; Q318-L327 VanDerWaalsContact CB-O 3.3Å; Q318-L327 WeakPolarHBondContact CB-O 3.34Å
319F89Confident87.8Confident33 Ų3355.9 Ų55.915%0.14538%0.378CS..EExtended strand (participates in β ladder)trans-85.3144.3166.4175.2-103.9000109.5C326 L327 E332 D344F319-C326 CarbonylContact O-C 3.57Å; F319-C326 WeakPolarHBondContact O-CA 3.44Å; F319-L327 HydrophobicContact CB-CB 4.4Å; F319-L327 HydrophobicContact CD1-CB 4.29Å; F319-L327 HydrophobicContact CD1-CD2 4.43Å; F319-L327 PolarHBondContact N-O 3.35Å; F319-L327 PolarHBondContact O-N 3.49Å; F319-E332 HydrophobicContact CB-CB 4.48Å; F319-E332 HydrophobicContact CD2-CB 4.31Å; F319-E332 HydrophobicContact CD2-CG 3.86Å; F319-E332 WeakPolarHBondContact CD2-OE2 3.47Å; F319-E332 VanDerWaalsContact CE2-CD 3.4Å; F319-E332 HydrophobicContact CE2-CG 3.9Å; F319-E332 WeakPolarHBondContact CE2-OE1 3.48Å; F319-E332 HydrophobicContact CG-CB 4.26Å; F319-E332 HydrophobicContact CG-CG 4.23Å; F319-E332 HydrophobicContact CZ-CG 4.3Å; F319-D344 HydrophobicContact CE1-CB 4.21Å
320S90.1Very high87.8Confident69 Ų6952.6 Ų52.648%0.48336%0.36SS..EExtended strand (participates in β ladder)trans-103.5113.6172.8-178.20000109
321C90.4Very high87.8Confident1 Ų150.4 Ų50.41%0.00734%0.344CS..  trans-61.2157.9166.5-52.40000109.9E308 N323 G324 C325 C339E308-C321 PolarHBondContact OE2-SG 3.14Å; C321-N323 VanDerWaalsContact C-N 3.26Å; C321-N323 WeakPolarHBondContact CB-OD1 3.33Å; C321-N323 PolarHBondContact O-N 2.73Å; C321-G324 PolarHBondContact O-N 3.22Å; C321-C325 PolarHBondContact N-O 3.34Å; C321-C339 HydrophobicContact CB-CB 3.81Å; C321-C339 WeakPolarHBondContact CB-SG 3.36Å; C321-C339 WeakPolarHBondContact SG-CB 3.46Å; C321-C339 CovalentContact SG-SG 2.04Å; C321-C339 PolarHBondContact SG-SG 2.9Å
322T91.1Very high88.1Confident117 Ų11747.1 Ų47.172%0.71831%0.306SS*.THydrogen-bonded Turntrans-65.6-29.5-177.2-57.80000112.5G324 D341 S343T322-G324 PolarHBondContact O-N 3.39Å; T322-D341 WeakPolarHBondContact CB-OD2 3.48Å; T322-D341 PolarHBondContact N-OD2 3.44Å; T322-S343 WeakPolarHBondContact CB-OG 3.39Å; T322-S343 PolarHBondContact N-OG 2.74Å; T322-S343 PolarHBondContact OG1-OG 2.82Å
323N88.8Confident88.4Confident70 Ų7044 Ų4437%0.37429%0.287SS..THydrogen-bonded Turntrans-66.2-7.1171.266.112.3000114.4E308 C321 C325 D341E308-N323 PolarHBondContact OE2-ND2 3.1Å; C321-N323 VanDerWaalsContact C-N 3.26Å; C321-N323 WeakPolarHBondContact CB-OD1 3.33Å; C321-N323 PolarHBondContact O-N 2.73Å; N323-C325 VanDerWaalsContact CG-SG 3.58Å; N323-C325 VanDerWaalsContact OD1-CB 3.24Å; N323-C325 WeakPolarHBondContact OD1-CB 3.45Å; N323-C325 PolarHBondContact OD1-N 2.83Å; N323-C325 PolarHBondContact OD1-SG 2.93Å; N323-D341 VanDerWaalsContact CB-OD2 3.3Å; N323-D341 WeakPolarHBondContact CB-OD2 3.4Å; N323-D341 PolarHBondContact N-OD2 2.91Å
324G88.6Confident88.5Confident41 Ų4140.3 Ų40.342%0.42326%0.261SS..SBendtrans83.215.2-178.300000115.1C321 T322C321-G324 PolarHBondContact O-N 3.22Å; T322-G324 PolarHBondContact O-N 3.39Å
325C93.2Very high88.7Confident9 Ų947 Ų476%0.06129%0.285CS..  trans-90.7154.9171.5-53.80000111.4E308 C310 C321 N323E308-C325 HydrophobicContact CB-CB 3.84Å; E308-C325 HydrophobicContact CG-CB 3.88Å; E308-C325 WeakPolarHBondContact OE2-CB 3.3Å; C310-C325 HydrophobicContact CB-CB 3.97Å; C310-C325 WeakPolarHBondContact CB-SG 3.04Å; C310-C325 WeakPolarHBondContact SG-CB 3.1Å; C310-C325 CovalentContact SG-SG 2.03Å; C310-C325 PolarHBondContact SG-SG 3.28Å; C321-C325 PolarHBondContact N-O 3.34Å; N323-C325 VanDerWaalsContact CG-SG 3.58Å; N323-C325 VanDerWaalsContact OD1-CB 3.24Å; N323-C325 WeakPolarHBondContact OD1-CB 3.45Å; N323-C325 PolarHBondContact OD1-N 2.83Å; N323-C325 PolarHBondContact OD1-SG 2.93Å
326C92.3Very high89Confident2 Ų251.8 Ų51.81%0.01430%0.296CS..EExtended strand (participates in β ladder)trans-105.2130.1-174.7-51.30000111.3E308 V309 V312 C314 Q318 F319E308-C326 CarbonylContact C-O 3.4Å; E308-C326 WeakPolarHBondContact CA-O 3.23Å; V309-C326 PolarHBondContact N-O 3.34Å; V309-C326 PolarHBondContact O-N 2.9Å; V312-C326 PolarHBondContact O-SG 2.85Å; V312-C326 VanDerWaalsContact O-SG 3.35Å; C314-C326 WeakPolarHBondContact CA-SG 3.45Å; C314-C326 HydrophobicContact CB-CB 3.82Å; C314-C326 WeakPolarHBondContact CB-SG 3.21Å; C314-C326 PolarHBondContact N-SG 3.39Å; C314-C326 WeakPolarHBondContact SG-CA 3.36Å; C314-C326 WeakPolarHBondContact SG-CB 3.32Å; C314-C326 CovalentContact SG-SG 2.04Å; C314-C326 PolarHBondContact SG-SG 3.39Å; Q318-C326 HydrophobicContact CB-CB 4.42Å; F319-C326 CarbonylContact O-C 3.57Å; F319-C326 WeakPolarHBondContact O-CA 3.44Å
327L91.1Very high89.7Confident3 Ų353.8 Ų53.82%0.01630%0.296CS..EExtended strand (participates in β ladder)trans-116.4155.8176.8-171.465.1000109.7Q318 F319 R329 L331 Q338 D344Q318-L327 CarbonylContact C-O 3.54Å; Q318-L327 VanDerWaalsContact CA-O 3.24Å; Q318-L327 WeakPolarHBondContact CA-O 3.38Å; Q318-L327 VanDerWaalsContact CB-O 3.3Å; Q318-L327 WeakPolarHBondContact CB-O 3.34Å; F319-L327 HydrophobicContact CB-CB 4.4Å; F319-L327 HydrophobicContact CD1-CB 4.29Å; F319-L327 HydrophobicContact CD1-CD2 4.43Å; F319-L327 PolarHBondContact N-O 3.35Å; F319-L327 PolarHBondContact O-N 3.49Å; L327-R329 PolarHBondContact O-N 2.03Å; L327-L331 HydrophobicContact CD1-CB 4.5Å; L327-L331 HydrophobicContact CD1-CD1 3.68Å; L327-L331 HydrophobicContact CD2-CB 4.01Å; L327-L331 HydrophobicContact CG-CB 4.11Å; L327-L331 HydrophobicContact CG-CD1 4.06Å; L327-Q338 HydrophobicContact CD1-CB 3.65Å; L327-Q338 HydrophobicContact CD2-CB 4.19Å; L327-D344 HydrophobicContact CD2-CB 3.82Å
328D88.6Confident90.4Very high58 Ų5852.7 Ų52.731%0.3128%0.279SS..EExtended strand (participates in β ladder)trans-64.5131.4168.7-170.6-77.1000109.7G330 L331D328-G330 PolarHBondContact O-N 2.86Å; D328-G330 WeakPolarHBondContact OD1-CA 3.07Å; D328-G330 PolarHBondContact OD1-N 3.34Å; D328-L331 HydrophobicContact CB-CD1 4Å; D328-L331 HydrophobicContact CB-CG 4.22Å; D328-L331 WeakPolarHBondContact O-CB 3.5Å; D328-L331 PolarHBondContact O-N 3.23Å
329R88.9Confident90.6Very high43 Ų4349.2 Ų49.216%0.16226%0.263CS..THydrogen-bonded Turntrans-65.6-20.3-175.3-164.7170.8-154.6175.3-0.8112.9D76 S316 G317 L327 L331D76-R329 IonicContact OD1-NH1 2.77Å; D76-R329 IonicContact OD1-NH2 2.67Å; D76-R329 IonicContact OD2-CZ 3.08Å; D76-R329 IonicContact OD2-NH1 3.25Å; D76-R329 IonicContact OD2-NH2 2.79Å; D76-R329 PolarHBondContact OD2-NH2 2.82Å; S316-R329 PolarHBondContact O-NH1 3.46Å; G317-R329 WeakPolarHBondContact O-CB 3.44Å; G317-R329 PolarHBondContact O-N 3.17Å; L327-R329 PolarHBondContact O-N 2.03Å; R329-L331 PolarHBondContact O-N 3.22Å
330G88.8Confident90.8Very high10 Ų1052.3 Ų52.310%0.10329%0.289CS..THydrogen-bonded Turntrans-71.2-10.7172.400000114.4K244 D328K244-G330 VanDerWaalsContact CD-O 3.26Å; K244-G330 WeakPolarHBondContact CD-O 3.25Å; K244-G330 PolarHBondContact NZ-O 2.81Å; D328-G330 PolarHBondContact O-N 2.86Å; D328-G330 WeakPolarHBondContact OD1-CA 3.07Å; D328-G330 PolarHBondContact OD1-N 3.34Å
331L90.8Very high90.8Very high29 Ų2952.1 Ų52.115%0.15228%0.283CS..THydrogen-bonded Turntrans-92.9-34.7177.9-60.4170.3000112.7K244 P306 L327 D328 R329 C333 D334K244-L331 PolarHBondContact NZ-O 3.14Å; P306-L331 HydrophobicContact CB-CD1 3.74Å; P306-L331 HydrophobicContact CG-CD1 4.02Å; P306-L331 HydrophobicContact CG-CD2 4.23Å; L327-L331 HydrophobicContact CD1-CB 4.5Å; L327-L331 HydrophobicContact CD1-CD1 3.68Å; L327-L331 HydrophobicContact CD2-CB 4.01Å; L327-L331 HydrophobicContact CG-CB 4.11Å; L327-L331 HydrophobicContact CG-CD1 4.06Å; D328-L331 HydrophobicContact CB-CD1 4Å; D328-L331 HydrophobicContact CB-CG 4.22Å; D328-L331 WeakPolarHBondContact O-CB 3.5Å; D328-L331 PolarHBondContact O-N 3.23Å; R329-L331 PolarHBondContact O-N 3.22Å; L331-C333 PolarHBondContact O-N 3.44Å; L331-D334 WeakPolarHBondContact CD2-OD2 3.29Å; L331-D334 VanDerWaalsContact O-CB 3.23Å; L331-D334 WeakPolarHBondContact O-CB 3.5Å; L331-D334 PolarHBondContact O-N 2.82Å
332E92.1Very high90.8Very high11 Ų1152.9 Ų52.95%0.05129%0.291CS..THydrogen-bonded Turntrans-48119.1178-173-166.8169.400113.4K244 R273 F319K244-E332 WeakPolarHBondContact CE-O 3.32Å; K244-E332 PolarHBondContact NZ-O 2.87Å; R273-E332 IonicContact CZ-OE1 3.64Å; R273-E332 IonicContact CZ-OE2 3.57Å; R273-E332 IonicContact NE-OE1 3.89Å; R273-E332 PolarHBondContact NE-OE1 2.78Å; R273-E332 IonicContact NE-OE2 2.91Å; R273-E332 IonicContact NH1-OE1 3.51Å; R273-E332 PolarHBondContact NH1-OE1 2.9Å; R273-E332 IonicContact NH1-OE2 3.77Å; R273-E332 PolarHBondContact NH1-OE2 2.87Å; R273-E332 IonicContact NH2-OE1 2.68Å; R273-E332 PolarHBondContact NH2-OE1 2.94Å; R273-E332 IonicContact NH2-OE2 2.69Å; R273-E332 PolarHBondContact NH2-OE2 3.09Å; F319-E332 HydrophobicContact CB-CB 4.48Å; F319-E332 HydrophobicContact CD2-CB 4.31Å; F319-E332 HydrophobicContact CD2-CG 3.86Å; F319-E332 WeakPolarHBondContact CD2-OE2 3.47Å; F319-E332 VanDerWaalsContact CE2-CD 3.4Å; F319-E332 HydrophobicContact CE2-CG 3.9Å; F319-E332 WeakPolarHBondContact CE2-OE1 3.48Å; F319-E332 HydrophobicContact CG-CB 4.26Å; F319-E332 HydrophobicContact CG-CG 4.23Å; F319-E332 HydrophobicContact CZ-CG 4.3Å
333C93.4Very high90.9Very high9 Ų947.8 Ų47.86%0.06126%0.259CS..THydrogen-bonded Turntrans65.246.1-172.6-53.60000114.9K244 P247 R273 L331 D344 E345 C348K244-C333 VanDerWaalsContact CE-O 3.28Å; K244-C333 WeakPolarHBondContact CE-O 3.16Å; P247-C333 HydrophobicContact CB-CB 4.08Å; P247-C333 HydrophobicContact CG-CB 3.7Å; R273-C333 HydrophobicContact CG-CB 4.48Å; L331-C333 PolarHBondContact O-N 3.44Å; C333-D344 PolarHBondContact N-O 2.89Å; C333-E345 VanDerWaalsContact C-OE1 3.24Å; C333-E345 WeakPolarHBondContact CA-OE1 3.06Å; C333-E345 PolarHBondContact N-OE1 3Å; C333-E345 VanDerWaalsContact N-OE1 3.11Å; C333-C348 WeakPolarHBondContact CA-SG 3.38Å; C333-C348 HydrophobicContact CB-CB 3.82Å; C333-C348 WeakPolarHBondContact CB-SG 3.39Å; C333-C348 VanDerWaalsContact SG-CA 3.5Å; C333-C348 WeakPolarHBondContact SG-CB 3.39Å; C333-C348 CovalentContact SG-SG 2.03Å; C333-C348 PolarHBondContact SG-SG 3.05Å
334D90.3Very high91Very high50 Ų5044.5 Ų44.527%0.26724%0.242SC..SBendtrans-101.2-5169.875.913.4000115.2K244 L331 E336 Q338 E345K244-D334 HydrophobicContact CD-CB 4.4Å; L331-D334 WeakPolarHBondContact CD2-OD2 3.29Å; L331-D334 VanDerWaalsContact O-CB 3.23Å; L331-D334 WeakPolarHBondContact O-CB 3.5Å; L331-D334 PolarHBondContact O-N 2.82Å; D334-E336 PolarHBondContact OD1-N 3.47Å; D334-Q338 PolarHBondContact OD1-NE2 2.03Å; D334-Q338 PolarHBondContact OD2-NE2 3.43Å; D334-E345 PolarHBondContact N-OE1 2.97Å
335K89.9Confident91.3Very high189 Ų18945 Ų4582%0.82223%0.233SC*.SBendtrans79.85.5-178.4-47.3166.9-173.8167.80115.4E345K335-E345 VanDerWaalsContact CA-OE2 3.28Å; K335-E345 WeakPolarHBondContact CA-OE2 3.4Å; K335-E345 VanDerWaalsContact N-CD 3.25Å; K335-E345 PolarHBondContact N-OE1 2.99Å; K335-E345 PolarHBondContact N-OE2 3.27Å
336E90.3Very high91.2Very high141 Ų14151.3 Ų51.366%0.65926%0.262SS*.SBendtrans-106.6146.7165.4-67.4-175.3-173.100109.1D334 Q338 E345D334-E336 PolarHBondContact OD1-N 3.47Å; E336-Q338 PolarHBondContact O-NE2 2.81Å; E336-Q338 PolarHBondContact O-OE1 3.15Å; E336-E345 WeakPolarHBondContact O-CG 3.35Å
337Q92.4Very high91Very high127 Ų12756 Ų5659%0.59329%0.287SS*.  trans-95.7114.8179.1-178.8-179.8-6.300109.5C339Q337-C339 WeakPolarHBondContact CG-O 3.33Å; Q337-C339 PolarHBondContact NE2-O 2.96Å
338Q91.7Very high91Very high20 Ų2056.5 Ų56.59%0.09329%0.29CS..  trans-113.6-27.1176.2-48.693.315.500113.6L327 D334 E336 D344L327-Q338 HydrophobicContact CD1-CB 3.65Å; L327-Q338 HydrophobicContact CD2-CB 4.19Å; D334-Q338 PolarHBondContact OD1-NE2 2.03Å; D334-Q338 PolarHBondContact OD2-NE2 3.43Å; E336-Q338 PolarHBondContact O-NE2 2.81Å; E336-Q338 PolarHBondContact O-OE1 3.15Å; Q338-D344 WeakPolarHBondContact CA-OD2 3.4Å; Q338-D344 PolarHBondContact N-OD2 3.18Å; Q338-D344 PolarHBondContact OE1-OD2 3.11Å
339C91.4Very high91.1Very high1 Ų158.6 Ų58.61%0.00730%0.298CS..SBendtrans-71130.7165.2-660000109.5E308 C321 Q337 D341 G342 D344E308-C339 WeakPolarHBondContact OE2-CA 3.46Å; C321-C339 HydrophobicContact CB-CB 3.81Å; C321-C339 WeakPolarHBondContact CB-SG 3.36Å; C321-C339 WeakPolarHBondContact SG-CB 3.46Å; C321-C339 CovalentContact SG-SG 2.04Å; C321-C339 PolarHBondContact SG-SG 2.9Å; Q337-C339 WeakPolarHBondContact CG-O 3.33Å; Q337-C339 PolarHBondContact NE2-O 2.96Å; C339-D341 WeakPolarHBondContact CB-OD1 3.5Å; C339-D341 PolarHBondContact O-N 2.84Å; C339-G342 PolarHBondContact O-N 3.07Å; C339-D344 HydrophobicContact CB-CB 4.34Å; C339-D344 PolarHBondContact N-OD2 3.31Å
340S91.7Very high91.2Very high99 Ų9959.2 Ų59.269%0.69231%0.305SS*.THydrogen-bonded Turntrans-63.6-17.1179.5-63.40000113.6E308E308-S340 VanDerWaalsContact CD-N 3.34Å; E308-S340 WeakPolarHBondContact OE1-CB 3.43Å; E308-S340 PolarHBondContact OE1-N 3.23Å; E308-S340 PolarHBondContact OE1-OG 2.85Å; E308-S340 PolarHBondContact OE2-N 2.97Å
341D90.8Very high91.2Very high65 Ų6559.2 Ų59.235%0.34830%0.302SS..THydrogen-bonded Turntrans-98-12.1176.462.718.9000114.5T322 N323 C339 S343T322-D341 WeakPolarHBondContact CB-OD2 3.48Å; T322-D341 PolarHBondContact N-OD2 3.44Å; N323-D341 VanDerWaalsContact CB-OD2 3.3Å; N323-D341 WeakPolarHBondContact CB-OD2 3.4Å; N323-D341 PolarHBondContact N-OD2 2.91Å; C339-D341 WeakPolarHBondContact CB-OD1 3.5Å; C339-D341 PolarHBondContact O-N 2.84Å; D341-S343 VanDerWaalsContact OD1-CB 3.28Å; D341-S343 WeakPolarHBondContact OD1-CB 3.39Å; D341-S343 PolarHBondContact OD1-N 2.75Å; D341-S343 PolarHBondContact OD1-OG 3.34Å; D341-S343 PolarHBondContact OD2-OG 3.32Å; D341-S343 VanDerWaalsContact OD2-OG 3.12Å
342G90.6Very high91.3Very high17 Ų1758.3 Ų58.318%0.17530%0.297CS..  trans81.613.1-179.500000115.8C339 D344 E345 E346C339-G342 PolarHBondContact O-N 3.07Å; G342-D344 VanDerWaalsContact CA-OD1 3.32Å; G342-D344 WeakPolarHBondContact CA-OD1 3.38Å; G342-D344 PolarHBondContact O-N 2.97Å; G342-E345 PolarHBondContact O-N 2.98Å; G342-E346 PolarHBondContact O-N 2.71Å
343S92.4Very high91.3Very high9 Ų963.4 Ų63.46%0.06332%0.319CS..Hα-helixtrans-62.7-25.8-178-55.80000114.5T322 D341 E345T322-S343 WeakPolarHBondContact CB-OG 3.39Å; T322-S343 PolarHBondContact N-OG 2.74Å; T322-S343 PolarHBondContact OG1-OG 2.82Å; D341-S343 VanDerWaalsContact OD1-CB 3.28Å; D341-S343 WeakPolarHBondContact OD1-CB 3.39Å; D341-S343 PolarHBondContact OD1-N 2.75Å; D341-S343 PolarHBondContact OD1-OG 3.34Å; D341-S343 PolarHBondContact OD2-OG 3.32Å; D341-S343 VanDerWaalsContact OD2-OG 3.12Å; S343-E345 VanDerWaalsContact C-N 3.3Å
344D92.5Very high91.3Very high1 Ų163.6 Ų63.61%0.00532%0.32CS..Hα-helixtrans-63.7-30177.443.8-5.9000113.6F319 L327 C333 Q338 C339 G342F319-D344 HydrophobicContact CE1-CB 4.21Å; L327-D344 HydrophobicContact CD2-CB 3.82Å; C333-D344 PolarHBondContact N-O 2.89Å; Q338-D344 WeakPolarHBondContact CA-OD2 3.4Å; Q338-D344 PolarHBondContact N-OD2 3.18Å; Q338-D344 PolarHBondContact OE1-OD2 3.11Å; C339-D344 HydrophobicContact CB-CB 4.34Å; C339-D344 PolarHBondContact N-OD2 3.31Å; G342-D344 VanDerWaalsContact CA-OD1 3.32Å; G342-D344 WeakPolarHBondContact CA-OD1 3.38Å; G342-D344 PolarHBondContact O-N 2.97Å
345E93.2Very high91.4Very high51 Ų5161.2 Ų61.224%0.23831%0.307CS..Hα-helixtrans-111-11.3-177.5-68.4-61.5134.400114.1C333 D334 K335 E336 G342 S343 C348C333-E345 VanDerWaalsContact C-OE1 3.24Å; C333-E345 WeakPolarHBondContact CA-OE1 3.06Å; C333-E345 PolarHBondContact N-OE1 3Å; C333-E345 VanDerWaalsContact N-OE1 3.11Å; D334-E345 PolarHBondContact N-OE1 2.97Å; K335-E345 VanDerWaalsContact CA-OE2 3.28Å; K335-E345 WeakPolarHBondContact CA-OE2 3.4Å; K335-E345 VanDerWaalsContact N-CD 3.25Å; K335-E345 PolarHBondContact N-OE1 2.99Å; K335-E345 PolarHBondContact N-OE2 3.27Å; E336-E345 WeakPolarHBondContact O-CG 3.35Å; G342-E345 PolarHBondContact O-N 2.98Å; S343-E345 VanDerWaalsContact C-N 3.3Å; E345-C348 PolarHBondContact O-SG 3.15Å; E345-C348 VanDerWaalsContact O-SG 3.4Å
346E91.8Very high91.5Very high143 Ų14354.7 Ų54.767%0.66828%0.28SS*.Hα-helixtrans-65.9-43.6-171.7-171.1179.5-155.300113.8G342G342-E346 PolarHBondContact O-N 2.71Å
347N88.3Confident91.5Very high101 Ų10151.8 Ų51.854%0.5427%0.268SS..THydrogen-bonded Turntrans-96.63.8-167.9-73.4-64.8000115E349 D350 L351N347-E349 PolarHBondContact O-N 2.87Å; N347-D350 PolarHBondContact O-N 3.21Å; N347-L351 PolarHBondContact O-N 2.03Å; N347-L351 VanDerWaalsContact O-N 3.15Å
348C91Very high91.4Very high12 Ų1245.9 Ų45.98%0.08124%0.24CC..Hα-helixtrans-63.2-38.7-170.8-56.30000114.1P247 C333 E345 L351 N352P247-C348 HydrophobicContact CB-CB 3.89Å; P247-C348 HydrophobicContact CG-CB 4.37Å; C333-C348 WeakPolarHBondContact CA-SG 3.38Å; C333-C348 HydrophobicContact CB-CB 3.82Å; C333-C348 WeakPolarHBondContact CB-SG 3.39Å; C333-C348 VanDerWaalsContact SG-CA 3.5Å; C333-C348 WeakPolarHBondContact SG-CB 3.39Å; C333-C348 CovalentContact SG-SG 2.03Å; C333-C348 PolarHBondContact SG-SG 3.05Å; E345-C348 PolarHBondContact O-SG 3.15Å; E345-C348 VanDerWaalsContact O-SG 3.4Å; C348-L351 PolarHBondContact O-N 3.06Å; C348-N352 PolarHBondContact O-N 3.19Å; C348-N352 VanDerWaalsContact O-N 3.14Å
349E90.4Very high91.4Very high102 Ų10247.4 Ų47.448%0.47725%0.249SC..Hα-helixtrans-73.6-26.4177.6-80.3-68.616400113.2R249 N347 K353R249-E349 IonicContact NH2-OE1 2.84Å; N347-E349 PolarHBondContact O-N 2.87Å; E349-K353 WeakPolarHBondContact O-CD 2.98Å; E349-K353 VanDerWaalsContact O-CG 3.23Å; E349-K353 WeakPolarHBondContact O-CG 3.42Å; E349-K353 PolarHBondContact O-N 3.13Å
350D90.4Very high91.3Very high57 Ų5754.1 Ų54.131%0.30528%0.28SS..Hα-helixtrans-71.6-42172.1-161.667000110.3N347 N352 K353 N354N347-D350 PolarHBondContact O-N 3.21Å; D350-N352 PolarHBondContact O-N 2.85Å; D350-K353 PolarHBondContact O-N 2.77Å; D350-N354 WeakPolarHBondContact O-CB 2.94Å; D350-N354 VanDerWaalsContact O-CG 3.26Å; D350-N354 PolarHBondContact O-N 3.4Å; D350-N354 PolarHBondContact O-ND2 3.3Å; D350-N354 PolarHBondContact OD2-ND2 2.6Å
351L90.5Very high91.1Very high10 Ų1050.5 Ų50.55%0.05225%0.253CS..Hα-helixtrans-57.8-46.8176.3-167.768.4000111.8F57 I58 P247 C272 R273 N347 C348 N354 F355F57-L351 HydrophobicContact CD1-CD1 3.93Å; F57-L351 HydrophobicContact CD1-CG 4.44Å; F57-L351 HydrophobicContact CE1-CD1 3.52Å; F57-L351 HydrophobicContact CE1-CG 4.2Å; F57-L351 HydrophobicContact CZ-CD1 4.3Å; I58-L351 WeakPolarHBondContact O-CD1 3.23Å; P247-L351 HydrophobicContact CG-CD2 4.06Å; C272-L351 HydrophobicContact CB-CD2 4.23Å; C272-L351 WeakPolarHBondContact SG-CD2 3.4Å; R273-L351 HydrophobicContact CG-CD2 3.52Å; R273-L351 VanDerWaalsContact NE-CD2 3.35Å; N347-L351 PolarHBondContact O-N 2.03Å; N347-L351 VanDerWaalsContact O-N 3.15Å; C348-L351 PolarHBondContact O-N 3.06Å; L351-N354 PolarHBondContact O-N 3.41Å; L351-F355 WeakPolarHBondContact O-CB 3.39Å; L351-F355 PolarHBondContact O-N 3.1Å
352N92.4Very high90.9Very high9 Ų952.2 Ų52.25%0.04827%0.268CS..Hα-helixtrans-59.5-47.9174.9177.838000112.5P247 R249 C348 D350 N354 F355 Q356P247-N352 WeakPolarHBondContact O-CB 3.32Å; R249-N352 WeakPolarHBondContact CG-OD1 3.46Å; R249-N352 PolarHBondContact N-OD1 3.08Å; R249-N352 VanDerWaalsContact N-OD1 3.09Å; R249-N352 PolarHBondContact NE-ND2 3.24Å; C348-N352 PolarHBondContact O-N 3.19Å; C348-N352 VanDerWaalsContact O-N 3.14Å; D350-N352 PolarHBondContact O-N 2.85Å; N352-N354 VanDerWaalsContact C-N 3.32Å; N352-N354 PolarHBondContact O-N 2.77Å; N352-F355 PolarHBondContact O-N 2.92Å; N352-Q356 VanDerWaalsContact O-CG 3.29Å; N352-Q356 WeakPolarHBondContact O-CG 3.4Å; N352-Q356 PolarHBondContact O-N 3.16Å
353K92.4Very high90.6Very high118 Ų11853.5 Ų53.551%0.51327%0.272SS..Hα-helixtrans-59.5-43.5177.7-71.3163.1-166.3161.90111.7E349 D350 Q356 I357E349-K353 WeakPolarHBondContact O-CD 2.98Å; E349-K353 VanDerWaalsContact O-CG 3.23Å; E349-K353 WeakPolarHBondContact O-CG 3.42Å; E349-K353 PolarHBondContact O-N 3.13Å; D350-K353 PolarHBondContact O-N 2.77Å; K353-Q356 PolarHBondContact O-N 3.42Å; K353-I357 WeakPolarHBondContact O-CG1 3.3Å; K353-I357 PolarHBondContact O-N 2.79Å
354N92.4Very high90.2Very high13 Ų1356.5 Ų56.57%0.0729%0.287CS..Hα-helixtrans-67-38.5179.6-69.5-42.4000112.1F57 K60 D350 L351 N352 I357F57-N354 HydrophobicContact CE1-CB 4.33Å; F57-N354 HydrophobicContact CZ-CB 4.12Å; K60-N354 HydrophobicContact CB-CB 3.89Å; K60-N354 HydrophobicContact CD-CB 4.11Å; K60-N354 WeakPolarHBondContact CD-OD1 3.38Å; D350-N354 WeakPolarHBondContact O-CB 2.94Å; D350-N354 VanDerWaalsContact O-CG 3.26Å; D350-N354 PolarHBondContact O-N 3.4Å; D350-N354 PolarHBondContact O-ND2 3.3Å; D350-N354 PolarHBondContact OD2-ND2 2.6Å; L351-N354 PolarHBondContact O-N 3.41Å; N352-N354 VanDerWaalsContact C-N 3.32Å; N352-N354 PolarHBondContact O-N 2.77Å; N354-I357 PolarHBondContact O-N 3.42Å
355F92.7Very high89.5Confident0 Ų064.3 Ų64.30%032%0.324CS..Hα-helixtrans-67.9-38.6174.8-170.4-110.5000112.6T47 V51 F57 C248 F252 G270 L351 N352 I357 L358 L359T47-F355 HydrophobicContact CG2-CD2 4.29Å; T47-F355 HydrophobicContact CG2-CE2 3.6Å; T47-F355 HydrophobicContact CG2-CZ 4.13Å; V51-F355 HydrophobicContact CG1-CZ 4.45Å; V51-F355 HydrophobicContact CG2-CE2 4.12Å; V51-F355 HydrophobicContact CG2-CZ 4.19Å; F57-F355 HydrophobicContact CB-CD2 3.68Å; F57-F355 HydrophobicContact CB-CE2 3.82Å; F57-F355 HydrophobicContact CD1-CB 3.86Å; F57-F355 AromaticContact CD1-CD2 3.55Å; F57-F355 HydrophobicContact CD1-CD2 3.55Å; F57-F355 HydrophobicContact CD1-CG 4.11Å; F57-F355 HydrophobicContact CE1-CB 3.94Å; F57-F355 HydrophobicContact CE1-CD2 4.34Å; F57-F355 AromaticContact CG-CD2 3.73Å; F57-F355 HydrophobicContact CG-CD2 3.73Å; F57-F355 HydrophobicContact CG-CE2 4.36Å; C248-F355 HydrophobicContact CB-CB 4.33Å; C248-F355 HydrophobicContact CB-CD1 3.62Å; C248-F355 HydrophobicContact CB-CE1 4.15Å; C248-F355 HydrophobicContact CB-CG 4.1Å; C248-F355 VanDerWaalsContact SG-CB 3.55Å; F252-F355 AromaticContact CE2-CE1 3.93Å; F252-F355 HydrophobicContact CE2-CE1 3.93Å; F252-F355 AromaticContact CE2-CZ 3.78Å; F252-F355 HydrophobicContact CE2-CZ 3.78Å; F252-F355 HydrophobicContact CZ-CE1 4.38Å; F252-F355 HydrophobicContact CZ-CZ 4.05Å; G270-F355 WeakPolarHBondContact O-CE1 3.37Å; L351-F355 WeakPolarHBondContact O-CB 3.39Å; L351-F355 PolarHBondContact O-N 3.1Å; N352-F355 PolarHBondContact O-N 2.92Å; F355-I357 VanDerWaalsContact C-N 3.29Å; F355-I357 PolarHBondContact O-N 2.81Å; F355-L358 WeakPolarHBondContact O-CB 3.43Å; F355-L358 PolarHBondContact O-N 2.9Å; F355-L359 HydrophobicContact CD1-CD1 4.01Å; F355-L359 HydrophobicContact CD1-CG 4.33Å; F355-L359 HydrophobicContact CE1-CD1 3.66Å; F355-L359 HydrophobicContact CE1-CD2 4.27Å; F355-L359 HydrophobicContact CE1-CG 4.04Å; F355-L359 HydrophobicContact CZ-CD1 4.42Å; F355-L359 HydrophobicContact CZ-CD2 4.21Å; F355-L359 HydrophobicContact CZ-CG 4.4Å; F355-L359 PolarHBondContact O-N 3.01Å
356Q91.8Very high88.9Confident53 Ų5366 Ų6625%0.24833%0.332CS..Hα-helixtrans-63.2-32.6175.4-73-68.4-49.500113R249 N352 K353 L358 Q360R249-Q356 PolarHBondContact O-NE2 2.75Å; R249-Q356 VanDerWaalsContact O-NE2 3.11Å; N352-Q356 VanDerWaalsContact O-CG 3.29Å; N352-Q356 WeakPolarHBondContact O-CG 3.4Å; N352-Q356 PolarHBondContact O-N 3.16Å; K353-Q356 PolarHBondContact O-N 3.42Å; Q356-L358 PolarHBondContact O-N 3.44Å; Q356-Q360 WeakPolarHBondContact O-CB 3.42Å; Q356-Q360 WeakPolarHBondContact O-CG 3.01Å; Q356-Q360 PolarHBondContact O-N 2.82Å
357I91.1Very high88.5Confident79 Ų7961.5 Ų61.541%0.40531%0.31SS..Hα-helixtrans-60.3-38.3171.9-68.3166.4000110.7F97 K353 N354 F355 Q360 I361F97-I357 HydrophobicContact CZ-CG2 4.4Å; K353-I357 WeakPolarHBondContact O-CG1 3.3Å; K353-I357 PolarHBondContact O-N 2.79Å; N354-I357 PolarHBondContact O-N 3.42Å; F355-I357 VanDerWaalsContact C-N 3.29Å; F355-I357 PolarHBondContact O-N 2.81Å; I357-Q360 PolarHBondContact O-N 3.47Å; I357-I361 WeakPolarHBondContact O-CG1 3.33Å
358L90.6Very high88.2Confident4 Ų457.3 Ų57.32%0.02129%0.288CS..Hα-helixtrans-70.9-45-178.6-64.4-177.6000112.8T47 F57 F83 F97 F99 F355 Q356 Q360 I361T47-L358 HydrophobicContact CG2-CB 3.91Å; T47-L358 HydrophobicContact CG2-CD1 4.3Å; F57-L358 HydrophobicContact CD2-CD1 4.1Å; F57-L358 HydrophobicContact CE2-CD1 4Å; F83-L358 HydrophobicContact CE2-CD2 3.93Å; F83-L358 HydrophobicContact CZ-CD1 4.2Å; F83-L358 HydrophobicContact CZ-CD2 3.61Å; F97-L358 HydrophobicContact CB-CD1 4.43Å; F97-L358 HydrophobicContact CD1-CD1 3.77Å; F97-L358 HydrophobicContact CD1-CD2 3.59Å; F97-L358 HydrophobicContact CD1-CG 3.88Å; F97-L358 HydrophobicContact CD2-CD2 3.87Å; F97-L358 HydrophobicContact CE1-CD1 4.25Å; F97-L358 HydrophobicContact CE1-CD2 3.51Å; F97-L358 HydrophobicContact CE1-CG 3.86Å; F97-L358 HydrophobicContact CE2-CD2 3.8Å; F97-L358 HydrophobicContact CG-CD1 4.23Å; F97-L358 HydrophobicContact CG-CD2 3.76Å; F97-L358 HydrophobicContact CG-CG 4.44Å; F97-L358 HydrophobicContact CZ-CD2 3.61Å; F97-L358 HydrophobicContact CZ-CG 4.41Å; F99-L358 HydrophobicContact CE2-CD1 3.57Å; F99-L358 HydrophobicContact CZ-CD1 3.56Å; F355-L358 WeakPolarHBondContact O-CB 3.43Å; F355-L358 PolarHBondContact O-N 2.9Å; Q356-L358 PolarHBondContact O-N 3.44Å; L358-Q360 PolarHBondContact O-N 2.79Å; L358-I361 HydrophobicContact CD2-CD1 3.8Å; L358-I361 WeakPolarHBondContact O-CB 3.36Å; L358-I361 WeakPolarHBondContact O-CG1 3.22Å; L358-I361 PolarHBondContact O-N 3.15Å; L358-I361 VanDerWaalsContact O-N 3.12Å
359L90.4Very high88Confident52 Ų5260.2 Ų60.227%0.27230%0.297SS..Hα-helixtrans-63.9-20.9175.1-61.6-179.7000113.1T47 D48 F252 F355T47-L359 HydrophobicContact CG2-CD2 4.06Å; D48-L359 HydrophobicContact CB-CD2 4.12Å; F252-L359 HydrophobicContact CZ-CD2 4.24Å; F355-L359 HydrophobicContact CD1-CD1 4.01Å; F355-L359 HydrophobicContact CD1-CG 4.33Å; F355-L359 HydrophobicContact CE1-CD1 3.66Å; F355-L359 HydrophobicContact CE1-CD2 4.27Å; F355-L359 HydrophobicContact CE1-CG 4.04Å; F355-L359 HydrophobicContact CZ-CD1 4.42Å; F355-L359 HydrophobicContact CZ-CD2 4.21Å; F355-L359 HydrophobicContact CZ-CG 4.4Å; F355-L359 PolarHBondContact O-N 3.01Å
360Q89.4Confident88Confident141 Ų14155.4 Ų55.466%0.65927%0.274SS*.THydrogen-bonded Turntrans-88.3-2.8177.3-71.5171.72400113.8Q356 I357 L358 P362Q356-Q360 WeakPolarHBondContact O-CB 3.42Å; Q356-Q360 WeakPolarHBondContact O-CG 3.01Å; Q356-Q360 PolarHBondContact O-N 2.82Å; I357-Q360 PolarHBondContact O-N 3.47Å; L358-Q360 PolarHBondContact O-N 2.79Å; Q360-P362 WeakPolarHBondContact O-CD 3.44Å
361I88.4Confident87.9Confident24 Ų2453.6 Ų53.612%0.12327%0.266CS..SBendtrans-68.5115.4174.3-64.3-179.8000107.8V44 K114 F117 I357 L358 V363V44-I361 HydrophobicContact CG1-CG2 4.22Å; V44-I361 HydrophobicContact CG2-CD1 4.04Å; V44-I361 HydrophobicContact CG2-CG2 4.25Å; K114-I361 HydrophobicContact CD-CG2 3.49Å; K114-I361 VanDerWaalsContact CD-CG2 3.49Å; K114-I361 VanDerWaalsContact CE-CG2 3.42Å; F117-I361 HydrophobicContact CE1-CD1 4.29Å; F117-I361 HydrophobicContact CZ-CD1 4.36Å; I357-I361 WeakPolarHBondContact O-CG1 3.33Å; L358-I361 HydrophobicContact CD2-CD1 3.8Å; L358-I361 WeakPolarHBondContact O-CB 3.36Å; L358-I361 WeakPolarHBondContact O-CG1 3.22Å; L358-I361 PolarHBondContact O-N 3.15Å; L358-I361 VanDerWaalsContact O-N 3.12Å; I361-V363 WeakPolarHBondContact O-CG2 3.01Å; I361-V363 PolarHBondContact O-N 3.34Å
362P85.4Confident87.4Confident101 Ų10154.6 Ų54.666%0.65627%0.27SS*.  trans-69.8124.1-178.123.1-30.3000110.4K114 Q360K114-P362 VanDerWaalsContact NZ-CD 3.35Å; K114-P362 PolarHBondContact NZ-O 3.23Å; Q360-P362 WeakPolarHBondContact O-CD 3.44Å
363V84.8Confident87Confident44 Ų4458.4 Ų58.427%0.26729%0.287SS..  trans-110.7147.2178.9-1710000108.8V112 I361 E365 V368V112-V363 HydrophobicContact CB-CG1 3.67Å; V112-V363 HydrophobicContact CG1-CG1 3.56Å; V112-V363 HydrophobicContact CG2-CG1 3.68Å; I361-V363 WeakPolarHBondContact O-CG2 3.01Å; I361-V363 PolarHBondContact O-N 3.34Å; V363-E365 PolarHBondContact O-N 2.03Å; V363-V368 HydrophobicContact CG1-CG2 3.38Å
364D84.1Confident86.7Confident71 Ų7154.6 Ų54.638%0.3827%0.274SS..  trans-8689.7176.2-176.1-23.3000109.3Q366 K367 V368D364-Q366 PolarHBondContact O-N 2.78Å; D364-Q366 VanDerWaalsContact O-N 3.13Å; D364-Q366 WeakPolarHBondContact OD1-CB 3.47Å; D364-Q366 PolarHBondContact OD1-N 2.77Å; D364-K367 HydrophobicContact CB-CB 4.07Å; D364-K367 HydrophobicContact CB-CD 4.08Å; D364-K367 HydrophobicContact CB-CG 4.17Å; D364-K367 WeakPolarHBondContact O-CA 3.34Å; D364-K367 WeakPolarHBondContact O-CB 3.35Å; D364-K367 PolarHBondContact O-N 3.36Å; D364-K367 PolarHBondContact OD1-N 2.83Å; D364-K367 VanDerWaalsContact OD1-N 3.12Å; D364-K367 VanDerWaalsContact OD2-CD 3.23Å; D364-K367 WeakPolarHBondContact OD2-CD 3.41Å; D364-K367 VanDerWaalsContact OD2-CE 3.25Å; D364-K367 WeakPolarHBondContact OD2-CE 2.98Å; D364-K367 WeakPolarHBondContact OD2-CG 3.26Å; D364-V368 WeakPolarHBondContact O-CG2 3.39Å; D364-V368 PolarHBondContact O-N 3.46Å
365E78.4Confident86.3Confident166 Ų16658.1 Ų58.178%0.77629%0.289SS*.Hα-helixtrans-51.8-31.2-179.5-68.9177.6-16900113.6V363 V368 R369V363-E365 PolarHBondContact O-N 2.03Å; E365-V368 WeakPolarHBondContact O-CB 3.19Å; E365-R369 WeakPolarHBondContact O-CB 3.03Å; E365-R369 PolarHBondContact O-N 3.37Å
366Q80.1Confident86Confident87 Ų8761.3 Ų61.341%0.40731%0.309SS..Hα-helixtrans-71.7-39.4177.6-172.8175.88.800111.1D364 C370 T419D364-Q366 PolarHBondContact O-N 2.78Å; D364-Q366 VanDerWaalsContact O-N 3.13Å; D364-Q366 WeakPolarHBondContact OD1-CB 3.47Å; D364-Q366 PolarHBondContact OD1-N 2.77Å; Q366-C370 PolarHBondContact O-SG 3.46Å; Q366-T419 PolarHBondContact NE2-O 3Å
367K82.9Confident85.6Confident47 Ų4758.9 Ų58.920%0.20430%0.298CS..Hα-helixtrans-68-46.4171.7-72.8-176.9-179.1-157.30112.1D364 R369 C370 T371 V423 D427D364-K367 HydrophobicContact CB-CB 4.07Å; D364-K367 HydrophobicContact CB-CD 4.08Å; D364-K367 HydrophobicContact CB-CG 4.17Å; D364-K367 WeakPolarHBondContact O-CA 3.34Å; D364-K367 WeakPolarHBondContact O-CB 3.35Å; D364-K367 PolarHBondContact O-N 3.36Å; D364-K367 PolarHBondContact OD1-N 2.83Å; D364-K367 VanDerWaalsContact OD1-N 3.12Å; D364-K367 VanDerWaalsContact OD2-CD 3.23Å; D364-K367 WeakPolarHBondContact OD2-CD 3.41Å; D364-K367 VanDerWaalsContact OD2-CE 3.25Å; D364-K367 WeakPolarHBondContact OD2-CE 2.98Å; D364-K367 WeakPolarHBondContact OD2-CG 3.26Å; K367-R369 PolarHBondContact O-N 3.14Å; K367-C370 PolarHBondContact O-N 2.98Å; K367-C370 VanDerWaalsContact O-N 3.15Å; K367-T371 WeakPolarHBondContact O-CG2 3.28Å; K367-T371 PolarHBondContact O-N 3.44Å; K367-T371 PolarHBondContact O-OG1 3.31Å; K367-V423 HydrophobicContact CG-CG2 4.06Å; K367-D427 HydrophobicContact CD-CB 4.36Å; K367-D427 IonicContact NZ-OD1 2.77Å; K367-D427 PolarHBondContact NZ-OD1 3.28Å; K367-D427 IonicContact NZ-OD2 3.95Å
368V81.6Confident85.1Confident13 Ų1357.6 Ų57.68%0.07929%0.292CS..Hα-helixtrans-43-65.3174.2171.60000108.5R110 V112 V363 D364 E365 C370 T371R110-V368 VanDerWaalsContact NH2-CG1 3.35Å; R110-V368 PolarHBondContact NH2-O 3.33Å; V112-V368 HydrophobicContact CB-CG2 4.35Å; V112-V368 HydrophobicContact CG1-CG2 3.99Å; V112-V368 HydrophobicContact CG2-CB 4.42Å; V112-V368 HydrophobicContact CG2-CG2 3.48Å; V112-V368 VanDerWaalsContact CG2-CG2 3.48Å; V363-V368 HydrophobicContact CG1-CG2 3.38Å; D364-V368 WeakPolarHBondContact O-CG2 3.39Å; D364-V368 PolarHBondContact O-N 3.46Å; E365-V368 WeakPolarHBondContact O-CB 3.19Å; V368-C370 PolarHBondContact O-N 3.37Å; V368-C370 VanDerWaalsContact O-N 3.07Å; V368-T371 PolarHBondContact O-N 3.14Å; V368-T371 PolarHBondContact O-OG1 2.03Å
369R87.9Confident85Confident74 Ų7459.9 Ų59.928%0.27931%0.308SS..Hα-helixtrans-53.8-33.1-175.4175.4166-176.6-175.94.7115.1E365 K367 E407 N408 R409 F410E365-R369 WeakPolarHBondContact O-CB 3.03Å; E365-R369 PolarHBondContact O-N 3.37Å; K367-R369 PolarHBondContact O-N 3.14Å; R369-E407 HydrophobicContact CB-CB 4.38Å; R369-E407 HydrophobicContact CG-CB 3.74Å; R369-E407 WeakPolarHBondContact CG-O 3.09Å; R369-E407 PolarHBondContact NE-O 3.17Å; R369-E407 PolarHBondContact NH2-O 2.77Å; R369-N408 WeakPolarHBondContact O-CA 3.45Å; R369-N408 WeakPolarHBondContact O-CB 3.42Å; R369-N408 PolarHBondContact O-N 3.3Å; R369-R409 PolarHBondContact NH2-O 3.49Å; R369-F410 VanDerWaalsContact NH2-CE1 3.28Å
370C90.7Very high84.8Confident0 Ų062.1 Ų62.10%031%0.312CS..Hα-helixtrans-98.8-7.4-169-63.20000114.6Q366 K367 V368 Y388 P390 N408 C420 V423Q366-C370 PolarHBondContact O-SG 3.46Å; K367-C370 PolarHBondContact O-N 2.98Å; K367-C370 VanDerWaalsContact O-N 3.15Å; V368-C370 PolarHBondContact O-N 3.37Å; V368-C370 VanDerWaalsContact O-N 3.07Å; C370-Y388 HydrophobicContact CB-CD1 4.14Å; C370-P390 WeakPolarHBondContact O-CG 3.38Å; C370-N408 PolarHBondContact O-ND2 3.02Å; C370-C420 HydrophobicContact CB-CB 3.64Å; C370-C420 WeakPolarHBondContact CB-SG 3.4Å; C370-C420 WeakPolarHBondContact SG-CA 3.47Å; C370-C420 WeakPolarHBondContact SG-CB 3.29Å; C370-C420 CovalentContact SG-SG 2.03Å; C370-C420 PolarHBondContact SG-SG 3Å; C370-V423 HydrophobicContact CB-CB 4.08Å; C370-V423 HydrophobicContact CB-CG1 4.09Å; C370-V423 HydrophobicContact CB-CG2 3.79Å
371T86.9Confident84.8Confident20 Ų2061.6 Ų61.612%0.12331%0.31CS..Hα-helixtrans-91.7-11.5-179.451.90000114.8K367 V368 P390 V423 D427K367-T371 WeakPolarHBondContact O-CG2 3.28Å; K367-T371 PolarHBondContact O-N 3.44Å; K367-T371 PolarHBondContact O-OG1 3.31Å; V368-T371 PolarHBondContact O-N 3.14Å; V368-T371 PolarHBondContact O-OG1 2.03Å; T371-P390 HydrophobicContact CG2-CG 4.4Å; T371-V423 HydrophobicContact CG2-CG1 3.61Å; T371-D427 HydrophobicContact CG2-CB 4.27Å; T371-D427 WeakPolarHBondContact CG2-O 3.49Å
372E81.7Confident84.9Confident30 Ų3064.6 Ų64.614%0.1433%0.333CS..SBendtrans-75.6148.3-178.1-61.9-178.17300113.6R110 N406 N408R110-E372 IonicContact CZ-OE2 3.79Å; R110-E372 IonicContact NH1-OE1 2.77Å; R110-E372 IonicContact NH1-OE2 3.83Å; R110-E372 PolarHBondContact NH1-OE2 2.92Å; R110-E372 IonicContact NH2-OE2 3.55Å; R110-E372 PolarHBondContact NH2-OE2 2.81Å; E372-N406 VanDerWaalsContact CB-ND2 3.29Å; E372-N406 WeakPolarHBondContact CB-ND2 3.32Å; E372-N406 WeakPolarHBondContact OE1-CB 3.31Å; E372-N406 PolarHBondContact OE1-ND2 3.05Å; E372-N406 WeakPolarHBondContact OE2-CB 3.3Å; E372-N408 HydrophobicContact CB-CB 4.31Å; E372-N408 PolarHBondContact O-ND2 3.25Å
373H82.8Confident85.3Confident90 Ų9064.2 Ų64.242%0.41732%0.321SS..PPolyproline II helixtrans-65146.6163.6-60.1-77.2000111.1K375 N406H373-K375 PolarHBondContact O-N 2.64Å; H373-N406 PolarHBondContact O-ND2 3.03Å
374P86.8Confident85.9Confident37 Ų3765 Ų6524%0.2433%0.326CS..PPolyproline II helixtrans-65.2125.2179.427.5-34.8000110.6Y387 F398P374-Y387 HydrophobicContact CB-CD1 3.81Å; P374-Y387 HydrophobicContact CB-CD2 4.06Å; P374-Y387 HydrophobicContact CB-CE1 4.3Å; P374-Y387 HydrophobicContact CB-CG 3.66Å; P374-Y387 HydrophobicContact CG-CD1 3.8Å; P374-Y387 HydrophobicContact CG-CD2 3.8Å; P374-Y387 HydrophobicContact CG-CE1 3.78Å; P374-Y387 HydrophobicContact CG-CE2 3.79Å; P374-Y387 HydrophobicContact CG-CG 3.8Å; P374-F398 HydrophobicContact CB-CB 4.46Å; P374-F398 HydrophobicContact CB-CD1 4.1Å; P374-F398 HydrophobicContact CB-CD2 3.84Å; P374-F398 HydrophobicContact CB-CE1 4.2Å; P374-F398 HydrophobicContact CB-CE2 3.95Å; P374-F398 HydrophobicContact CB-CG 3.9Å; P374-F398 HydrophobicContact CB-CZ 4.11Å
375K84.8Confident86.4Confident88 Ų8863.6 Ų63.638%0.38332%0.317SS..  trans-100.1113.3175-72.8-177.5178.6178.70110.9H373 G377 N406H373-K375 PolarHBondContact O-N 2.64Å; K375-G377 VanDerWaalsContact C-N 3.34Å; K375-N406 HydrophobicContact CD-CB 4.41Å; K375-N406 PolarHBondContact N-OD1 3.23Å
376T85.2Confident87.3Confident67 Ų6757.9 Ų57.941%0.41129%0.288SS..  trans-61.5-41.9173-580000111.5N399 Y400 G401T376-N399 WeakPolarHBondContact CG2-O 3.42Å; T376-N399 PolarHBondContact OG1-O 2.88Å; T376-Y400 VanDerWaalsContact O-CD2 3.25Å; T376-Y400 WeakPolarHBondContact O-CD2 3.25Å; T376-G401 WeakPolarHBondContact O-CA 3.29Å; T376-G401 PolarHBondContact O-N 3.48Å
377G83.6Confident88Confident1 Ų155.8 Ų55.81%0.0128%0.277CS..  trans76.8172.9-174.900000113.4K375 C379K375-G377 VanDerWaalsContact C-N 3.34Å; G377-C379 PolarHBondContact O-N 3.4Å
378N81.3Confident88.4Confident52 Ų5253.7 Ų53.728%0.27827%0.268SS..SBendtrans-88.14.8-166.5-69.3-24.4000116N164 E165N164-N378 PolarHBondContact ND2-OD1 2.94Å; N164-N378 PolarHBondContact OD1-OD1 2.87Å; E165-N378 WeakPolarHBondContact CG-OD1 3.25Å; E165-N378 PolarHBondContact OE1-OD1 2.93Å
379C88Confident88.8Confident53 Ų5354.5 Ų54.536%0.35827%0.272SS..  trans-89.8155.9172.3-70.30000110.9G377 G401 C403G377-C379 PolarHBondContact O-N 3.4Å; C379-G401 CarbonylContact C-O 3.56Å; C379-G401 WeakPolarHBondContact CB-O 3.46Å; C379-G401 CarbonylContact O-C 3.59Å; C379-G401 WeakPolarHBondContact O-CA 3.32Å; C379-C403 HydrophobicContact CB-CB 3.93Å; C379-C403 WeakPolarHBondContact CB-SG 3.47Å; C379-C403 PolarHBondContact N-SG 3.31Å; C379-C403 VanDerWaalsContact N-SG 3.43Å; C379-C403 WeakPolarHBondContact SG-CB 3.42Å; C379-C403 CovalentContact SG-SG 2.03Å; C379-C403 PolarHBondContact SG-SG 3.46Å
380R85.7Confident88.8Confident98 Ų9851.3 Ų51.337%0.3726%0.261SS..  trans-105.911.6-171.5-61.1-173.1-176.9-91.5-4.7114.5D195 G401D195-R380 IonicContact OD1-CZ 3.62Å; D195-R380 IonicContact OD1-NH1 2.67Å; D195-R380 PolarHBondContact OD1-NH1 2.67Å; D195-R380 VanDerWaalsContact OD1-NH1 3.08Å; D195-R380 IonicContact OD1-NH2 3.88Å; D195-R380 IonicContact OD2-CZ 2.65Å; D195-R380 VanDerWaalsContact OD2-CZ 3.25Å; D195-R380 IonicContact OD2-NH1 3.17Å; D195-R380 PolarHBondContact OD2-NH1 2.98Å; D195-R380 IonicContact OD2-NH2 2.67Å; D195-R380 PolarHBondContact OD2-NH2 2.97Å; R380-G401 PolarHBondContact N-O 3.03Å
381E89.2Confident88.6Confident131 Ų13153.7 Ų53.761%0.61228%0.275SS*.  trans-70.6161.4170.2-64.4-64.5161.500110.2F383 G401E381-F383 HydrophobicContact CB-CD2 3.92Å; E381-F383 HydrophobicContact CB-CE2 3.39Å; E381-F383 HydrophobicContact CB-CZ 4.06Å; E381-F383 HydrophobicContact CG-CE2 4Å; E381-F383 HydrophobicContact CG-CZ 4.39Å; E381-G401 WeakPolarHBondContact CB-O 3.28Å; E381-G401 PolarHBondContact N-O 2.86Å; E381-G401 CarbonylContact O-C 3.57Å; E381-G401 VanDerWaalsContact O-CA 3.26Å; E381-G401 WeakPolarHBondContact O-CA 3.47Å
382S91.5Very high88.6Confident87 Ų8757.5 Ų57.561%0.60829%0.288SS*.  trans-123.187.7-179.8-167.20000111.4
383F94.1Very high89Confident92 Ų9260.8 Ų60.840%0.40430%0.303SS..EExtended strand (participates in β ladder)trans-98.3113.5174-59.9-74.9000110.2E381 K385 Y400E381-F383 HydrophobicContact CB-CD2 3.92Å; E381-F383 HydrophobicContact CB-CE2 3.39Å; E381-F383 HydrophobicContact CB-CZ 4.06Å; E381-F383 HydrophobicContact CG-CE2 4Å; E381-F383 HydrophobicContact CG-CZ 4.39Å; F383-K385 HydrophobicContact CB-CG 4.46Å; F383-K385 PolarHBondContact O-N 2.68Å; F383-Y400 HydrophobicContact CB-CD1 4.35Å; F383-Y400 HydrophobicContact CD2-CD1 4.22Å; F383-Y400 PolarHBondContact N-O 3.47Å; F383-Y400 PolarHBondContact O-N 2.89Å
384T95.9Very high89.5Confident61 Ų6161.4 Ų61.437%0.37431%0.305SS..EExtended strand (participates in β ladder)trans-60121.6165.3-75.70000109.2R397T384-R397 HydrophobicContact CG2-CG 4.41Å; T384-R397 PolarHBondContact OG1-NH2 2.82Å; T384-R397 VanDerWaalsContact OG1-NH2 3.09Å
385K96.3Very high89.8Confident41 Ų4159.8 Ų59.818%0.17829%0.294CS..EExtended strand (participates in β ladder)trans-130.3170.8172.6-62.6-62.7-177.6-169.40109.9F383 R397 F398 Y400 R409 D411F383-K385 HydrophobicContact CB-CG 4.46Å; F383-K385 PolarHBondContact O-N 2.68Å; K385-R397 CarbonylContact O-C 3.57Å; K385-R397 VanDerWaalsContact O-CA 3.3Å; K385-R397 WeakPolarHBondContact O-CA 3.48Å; K385-F398 HydrophobicContact CB-CD1 4.04Å; K385-F398 HydrophobicContact CB-CE1 3.6Å; K385-F398 HydrophobicContact CB-CZ 4.1Å; K385-F398 PolarHBondContact N-O 3.4Å; K385-F398 PolarHBondContact O-N 3.32Å; K385-Y400 HydrophobicContact CG-CD1 4.41Å; K385-Y400 HydrophobicContact CG-CG 4.41Å; K385-R409 HydrophobicContact CB-CG 3.89Å; K385-R409 HydrophobicContact CD-CG 4.35Å; K385-R409 HydrophobicContact CG-CG 3.88Å; K385-D411 IonicContact NZ-OD1 2.65Å; K385-D411 PolarHBondContact NZ-OD1 2.94Å
386W96.2Very high90.3Very high47 Ų4758.8 Ų58.818%0.17829%0.29CS..EExtended strand (participates in β ladder)trans-112.8144.5175.5-64.483.9000110.7C395 F396 R397 R409 F410 E413 C416W386-C395 HydrophobicContact CE3-CB 4.07Å; W386-F396 CarbonylContact C-O 3.54Å; W386-F396 VanDerWaalsContact CA-O 3.28Å; W386-F396 WeakPolarHBondContact CA-O 3.45Å; W386-R397 HydrophobicContact CD2-CG 3.75Å; W386-R397 HydrophobicContact CE3-CG 3.81Å; W386-R397 HydrophobicContact CH2-CG 3.65Å; W386-R397 HydrophobicContact CZ2-CG 3.54Å; W386-R397 HydrophobicContact CZ3-CG 3.77Å; W386-R409 CarbonylContact O-C 3.51Å; W386-R409 WeakPolarHBondContact O-CA 3.37Å; W386-F410 HydrophobicContact CB-CB 4.25Å; W386-F410 PolarHBondContact N-O 3.17Å; W386-F410 PolarHBondContact O-N 2.92Å; W386-E413 HydrophobicContact CD2-CB 3.88Å; W386-E413 HydrophobicContact CD2-CG 4.44Å; W386-E413 HydrophobicContact CE3-CB 3.84Å; W386-E413 HydrophobicContact CE3-CG 3.88Å; W386-E413 HydrophobicContact CH2-CB 3.75Å; W386-E413 HydrophobicContact CH2-CG 3.92Å; W386-E413 WeakPolarHBondContact CH2-OE2 3.41Å; W386-E413 HydrophobicContact CZ2-CB 3.82Å; W386-E413 HydrophobicContact CZ2-CG 4.5Å; W386-E413 HydrophobicContact CZ3-CB 3.76Å; W386-E413 VanDerWaalsContact CZ3-CD 3.47Å; W386-E413 HydrophobicContact CZ3-CG 3.59Å; W386-C416 HydrophobicContact CB-CB 4.2Å
387Y94.3Very high90.7Very high43 Ų4363.1 Ų63.117%0.16930%0.298CS..EExtended strand (participates in β ladder)trans-132.7153.2170.778.4-83.6000109.6P374 N389 C395 F396 F398 N408 C416P374-Y387 HydrophobicContact CB-CD1 3.81Å; P374-Y387 HydrophobicContact CB-CD2 4.06Å; P374-Y387 HydrophobicContact CB-CE1 4.3Å; P374-Y387 HydrophobicContact CB-CG 3.66Å; P374-Y387 HydrophobicContact CG-CD1 3.8Å; P374-Y387 HydrophobicContact CG-CD2 3.8Å; P374-Y387 HydrophobicContact CG-CE1 3.78Å; P374-Y387 HydrophobicContact CG-CE2 3.79Å; P374-Y387 HydrophobicContact CG-CG 3.8Å; Y387-N389 HydrophobicContact CE2-CB 4.09Å; Y387-C395 CarbonylContact O-C 3.5Å; Y387-C395 WeakPolarHBondContact O-CA 3.47Å; Y387-F396 HydrophobicContact CD1-CB 4.13Å; Y387-F396 WeakPolarHBondContact CD1-O 3.46Å; Y387-F396 HydrophobicContact CE1-CB 3.52Å; Y387-F396 PolarHBondContact N-O 3.47Å; Y387-F396 PolarHBondContact O-N 3.44Å; Y387-F398 HydrophobicContact CD1-CB 4.06Å; Y387-F398 AromaticContact CD1-CD1 3.75Å; Y387-F398 HydrophobicContact CD1-CD1 3.75Å; Y387-F398 HydrophobicContact CD1-CG 4.18Å; Y387-F398 HydrophobicContact CE1-CB 4.26Å; Y387-F398 HydrophobicContact CG-CD1 4.34Å; Y387-N408 WeakPolarHBondContact CA-O 3.38Å; Y387-N408 WeakPolarHBondContact CB-O 3.35Å; Y387-C416 VanDerWaalsContact C-SG 3.52Å
388Y93.1Very high91Very high2 Ų264.1 Ų64.11%0.00830%0.303CS..EExtended strand (participates in β ladder)trans-92.3134.9175.8-174.5-104.4000111.1C370 P390 Q393 N408 M417 C420 V423C370-Y388 HydrophobicContact CB-CD1 4.14Å; Y388-P390 HydrophobicContact CD1-CB 4.36Å; Y388-P390 HydrophobicContact CD1-CG 3.93Å; Y388-P390 HydrophobicContact CE1-CB 3.92Å; Y388-P390 HydrophobicContact CE1-CG 4Å; Y388-Q393 VanDerWaalsContact CE2-C 3.44Å; Y388-Q393 VanDerWaalsContact OH-CA 3.26Å; Y388-Q393 WeakPolarHBondContact OH-CA 3.45Å; Y388-Q393 WeakPolarHBondContact OH-CB 3.28Å; Y388-N408 PolarHBondContact N-OD1 3.47Å; Y388-N408 PolarHBondContact O-ND2 3Å; Y388-M417 HydrophobicContact CD2-SD 4.47Å; Y388-M417 HydrophobicContact CE2-SD 4.38Å; Y388-C420 HydrophobicContact CD1-CB 3.5Å; Y388-C420 HydrophobicContact CD2-CB 3.4Å; Y388-C420 VanDerWaalsContact CD2-CB 3.4Å; Y388-C420 HydrophobicContact CE1-CB 3.91Å; Y388-C420 WeakPolarHBondContact CE1-O 3.36Å; Y388-C420 HydrophobicContact CE2-CB 3.83Å; Y388-C420 HydrophobicContact CG-CB 3.2Å; Y388-C420 VanDerWaalsContact CZ-O 3.27Å; Y388-C420 PolarHBondContact OH-O 3.18Å; Y388-V423 HydrophobicContact CE1-CB 3.98Å; Y388-V423 WeakPolarHBondContact CE1-O 3.46Å; Y388-V423 PolarHBondContact OH-O 2.84Å
389N88.2Confident91.5Very high31 Ų3166 Ų6617%0.16631%0.313CS..EExtended strand (participates in β ladder)trans-109114.3169.3-175.4-45.5000109.3Y387 V391 Y392 Q393 K394 F396Y387-N389 HydrophobicContact CE2-CB 4.09Å; N389-V391 VanDerWaalsContact C-N 3.29Å; N389-V391 PolarHBondContact O-N 2.8Å; N389-V391 VanDerWaalsContact OD1-CB 3.27Å; N389-V391 WeakPolarHBondContact OD1-CB 3.48Å; N389-V391 PolarHBondContact OD1-N 3.3Å; N389-Y392 HydrophobicContact CB-CD2 4.24Å; N389-Y392 PolarHBondContact O-N 2.87Å; N389-Y392 PolarHBondContact OD1-N 3.11Å; N389-Q393 WeakPolarHBondContact O-CA 3.42Å; N389-Q393 PolarHBondContact O-N 3.26Å; N389-K394 PolarHBondContact N-O 3.46Å; N389-K394 PolarHBondContact O-N 3.48Å; N389-F396 HydrophobicContact CB-CD2 3.92Å; N389-F396 HydrophobicContact CB-CE2 3.86Å
390P88.6Confident91.7Very high7 Ų764.6 Ų64.65%0.04530%0.3CS..THydrogen-bonded Turntrans-72.3-14.5-177.8-13.226.2000115.5C370 T371 Y388 Q393 V423 T424 E425 I428C370-P390 WeakPolarHBondContact O-CG 3.38Å; T371-P390 HydrophobicContact CG2-CG 4.4Å; Y388-P390 HydrophobicContact CD1-CB 4.36Å; Y388-P390 HydrophobicContact CD1-CG 3.93Å; Y388-P390 HydrophobicContact CE1-CB 3.92Å; Y388-P390 HydrophobicContact CE1-CG 4Å; P390-Q393 WeakPolarHBondContact O-CG 3.45Å; P390-V423 HydrophobicContact CB-CG1 4.21Å; P390-V423 HydrophobicContact CG-CG1 4.14Å; P390-T424 CarbonylContact O-C 3.57Å; P390-E425 PolarHBondContact O-N 2.95Å; P390-I428 HydrophobicContact CB-CD1 3.92Å; P390-I428 HydrophobicContact CB-CG1 3.94Å; P390-I428 HydrophobicContact CG-CD1 4.06Å; P390-I428 HydrophobicContact CG-CG1 3.98Å
391V85.9Confident91.9Very high50 Ų5060 Ų6030%0.30328%0.283SS..THydrogen-bonded Turntrans-71.1-48.4173.2-174.20000109.6N389 I428N389-V391 VanDerWaalsContact C-N 3.29Å; N389-V391 PolarHBondContact O-N 2.8Å; N389-V391 VanDerWaalsContact OD1-CB 3.27Å; N389-V391 WeakPolarHBondContact OD1-CB 3.48Å; N389-V391 PolarHBondContact OD1-N 3.3Å; V391-I428 HydrophobicContact CG2-CD1 3.6Å
392Y86.5Confident91.9Very high100 Ų10055.3 Ų55.339%0.39227%0.27SS..THydrogen-bonded Turntrans-89-4.7177.8-52.1-55.6000113.8L135 N389 K394 F396L135-Y392 HydrophobicContact CD1-CD1 4.2Å; L135-Y392 HydrophobicContact CD1-CE1 3.38Å; L135-Y392 HydrophobicContact CD1-CE2 3.93Å; L135-Y392 WeakPolarHBondContact CD1-OH 3.23Å; L135-Y392 HydrophobicContact CD2-CE2 4.02Å; L135-Y392 HydrophobicContact CG-CE1 4.13Å; L135-Y392 HydrophobicContact CG-CE2 3.78Å; L135-Y392 VanDerWaalsContact CG-CZ 3.47Å; L135-Y392 VanDerWaalsContact CG-OH 3.3Å; L135-Y392 WeakPolarHBondContact CG-OH 3.13Å; N389-Y392 HydrophobicContact CB-CD2 4.24Å; N389-Y392 PolarHBondContact O-N 2.87Å; N389-Y392 PolarHBondContact OD1-N 3.11Å; Y392-K394 PolarHBondContact O-N 3.48Å; Y392-K394 VanDerWaalsContact O-N 3.14Å; Y392-F396 HydrophobicContact CD2-CE2 4.08Å; Y392-F396 HydrophobicContact CD2-CZ 4.03Å; Y392-F396 HydrophobicContact CG-CE2 4.41Å; Y392-F396 HydrophobicContact CG-CZ 4.22Å
393Q90.6Very high91.7Very high99 Ų9952.5 Ų52.546%0.46325%0.25SS..THydrogen-bonded Turntrans50.334.9-176.7-60.2175.618.600112.9Y388 N389 P390Y388-Q393 VanDerWaalsContact CE2-C 3.44Å; Y388-Q393 VanDerWaalsContact OH-CA 3.26Å; Y388-Q393 WeakPolarHBondContact OH-CA 3.45Å; Y388-Q393 WeakPolarHBondContact OH-CB 3.28Å; N389-Q393 WeakPolarHBondContact O-CA 3.42Å; N389-Q393 PolarHBondContact O-N 3.26Å; P390-Q393 WeakPolarHBondContact O-CG 3.45Å
394K93.1Very high91.2Very high103 Ų10355 Ų5545%0.44826%0.258SS..EExtended strand (participates in β ladder)trans-140.2150.7-169.9-175.9173.1179.3-176.90111.3N389 Y392 F396N389-K394 PolarHBondContact N-O 3.46Å; N389-K394 PolarHBondContact O-N 3.48Å; Y392-K394 PolarHBondContact O-N 3.48Å; Y392-K394 VanDerWaalsContact O-N 3.14Å; K394-F396 HydrophobicContact CB-CE2 3.95Å; K394-F396 HydrophobicContact CB-CZ 4.32Å; K394-F396 HydrophobicContact CD-CZ 4.49Å; K394-F396 HydrophobicContact CG-CE2 4.32Å; K394-F396 HydrophobicContact CG-CZ 4.49Å; K394-F396 VanDerWaalsContact O-CD2 3.3Å; K394-F396 WeakPolarHBondContact O-CD2 3.41Å; K394-F396 WeakPolarHBondContact O-CE2 3.3Å
395C94.8Very high90.6Very high2 Ų252.8 Ų52.81%0.01425%0.247CC..EExtended strand (participates in β ladder)trans-85.5139.1172.3-63.80000112.7W386 Y387 E413 C416 M417W386-C395 HydrophobicContact CE3-CB 4.07Å; Y387-C395 CarbonylContact O-C 3.5Å; Y387-C395 WeakPolarHBondContact O-CA 3.47Å; C395-E413 HydrophobicContact CB-CG 4.2Å; C395-C416 HydrophobicContact CB-CB 3.83Å; C395-C416 WeakPolarHBondContact CB-SG 3.48Å; C395-C416 WeakPolarHBondContact SG-CB 3.39Å; C395-C416 CovalentContact SG-SG 2.02Å; C395-C416 PolarHBondContact SG-SG 2.89Å; C395-M417 HydrophobicContact CB-CG 4.15Å; C395-M417 HydrophobicContact CB-SD 3.95Å; C395-M417 PolarHBondContact N-SD 3.18Å; C395-M417 VanDerWaalsContact N-SD 3.4Å; C395-M417 PolarHBondContact SG-N 3.16Å; C395-M417 PolarHBondContact SG-SD 2.87Å
396F93.4Very high90.1Very high68 Ų6851 Ų5130%0.29824%0.24SC..EExtended strand (participates in β ladder)trans-126.1154.2179.1-65.1-94.7000109.9W386 Y387 N389 Y392 K394W386-F396 CarbonylContact C-O 3.54Å; W386-F396 VanDerWaalsContact CA-O 3.28Å; W386-F396 WeakPolarHBondContact CA-O 3.45Å; Y387-F396 HydrophobicContact CD1-CB 4.13Å; Y387-F396 WeakPolarHBondContact CD1-O 3.46Å; Y387-F396 HydrophobicContact CE1-CB 3.52Å; Y387-F396 PolarHBondContact N-O 3.47Å; Y387-F396 PolarHBondContact O-N 3.44Å; N389-F396 HydrophobicContact CB-CD2 3.92Å; N389-F396 HydrophobicContact CB-CE2 3.86Å; Y392-F396 HydrophobicContact CD2-CE2 4.08Å; Y392-F396 HydrophobicContact CD2-CZ 4.03Å; Y392-F396 HydrophobicContact CG-CE2 4.41Å; Y392-F396 HydrophobicContact CG-CZ 4.22Å; K394-F396 HydrophobicContact CB-CE2 3.95Å; K394-F396 HydrophobicContact CB-CZ 4.32Å; K394-F396 HydrophobicContact CD-CZ 4.49Å; K394-F396 HydrophobicContact CG-CE2 4.32Å; K394-F396 HydrophobicContact CG-CZ 4.49Å; K394-F396 VanDerWaalsContact O-CD2 3.3Å; K394-F396 WeakPolarHBondContact O-CD2 3.41Å; K394-F396 WeakPolarHBondContact O-CE2 3.3Å
397R93.8Very high89.9Confident157 Ų15753.4 Ų53.459%0.59225%0.253SS*.EExtended strand (participates in β ladder)trans-83.4142.3175.1-69.9175.460-159.2-3.7110.4T384 K385 W386T384-R397 HydrophobicContact CG2-CG 4.41Å; T384-R397 PolarHBondContact OG1-NH2 2.82Å; T384-R397 VanDerWaalsContact OG1-NH2 3.09Å; K385-R397 CarbonylContact O-C 3.57Å; K385-R397 VanDerWaalsContact O-CA 3.3Å; K385-R397 WeakPolarHBondContact O-CA 3.48Å; W386-R397 HydrophobicContact CD2-CG 3.75Å; W386-R397 HydrophobicContact CE3-CG 3.81Å; W386-R397 HydrophobicContact CH2-CG 3.65Å; W386-R397 HydrophobicContact CZ2-CG 3.54Å; W386-R397 HydrophobicContact CZ3-CG 3.77Å
398F91.6Very high89.8Confident23 Ų2351.3 Ų51.310%0.10125%0.245CC..EExtended strand (participates in β ladder)trans-139.6164.6167.479.9-71.9000110.5P374 K385 Y387 R409P374-F398 HydrophobicContact CB-CB 4.46Å; P374-F398 HydrophobicContact CB-CD1 4.1Å; P374-F398 HydrophobicContact CB-CD2 3.84Å; P374-F398 HydrophobicContact CB-CE1 4.2Å; P374-F398 HydrophobicContact CB-CE2 3.95Å; P374-F398 HydrophobicContact CB-CG 3.9Å; P374-F398 HydrophobicContact CB-CZ 4.11Å; K385-F398 HydrophobicContact CB-CD1 4.04Å; K385-F398 HydrophobicContact CB-CE1 3.6Å; K385-F398 HydrophobicContact CB-CZ 4.1Å; K385-F398 PolarHBondContact N-O 3.4Å; K385-F398 PolarHBondContact O-N 3.32Å; Y387-F398 HydrophobicContact CD1-CB 4.06Å; Y387-F398 AromaticContact CD1-CD1 3.75Å; Y387-F398 HydrophobicContact CD1-CD1 3.75Å; Y387-F398 HydrophobicContact CD1-CG 4.18Å; Y387-F398 HydrophobicContact CE1-CB 4.26Å; Y387-F398 HydrophobicContact CG-CD1 4.34Å; F398-R409 HydrophobicContact CE1-CB 4.46Å; F398-R409 HydrophobicContact CE1-CG 4.16Å; F398-R409 HydrophobicContact CZ-CB 4.21Å; F398-R409 HydrophobicContact CZ-CG 3.87Å
399N90.8Very high89.9Confident91 Ų9154.6 Ų54.649%0.48726%0.257SS..EExtended strand (participates in β ladder)trans-95.8120.2173.2-65-32.8000108.7T376T376-N399 WeakPolarHBondContact CG2-O 3.42Å; T376-N399 PolarHBondContact OG1-O 2.88Å
400Y92.3Very high90.3Very high23 Ų2353.6 Ų53.69%0.0925%0.251CS..EExtended strand (participates in β ladder)trans-96.6131.8175.5170.2-117.6000110.1T376 F383 K385 G402 C403 Y404 R409T376-Y400 VanDerWaalsContact O-CD2 3.25Å; T376-Y400 WeakPolarHBondContact O-CD2 3.25Å; F383-Y400 HydrophobicContact CB-CD1 4.35Å; F383-Y400 HydrophobicContact CD2-CD1 4.22Å; F383-Y400 PolarHBondContact N-O 3.47Å; F383-Y400 PolarHBondContact O-N 2.89Å; K385-Y400 HydrophobicContact CG-CD1 4.41Å; K385-Y400 HydrophobicContact CG-CG 4.41Å; Y400-G402 VanDerWaalsContact CE1-CA 3.45Å; Y400-G402 VanDerWaalsContact CZ-C 3.49Å; Y400-G402 PolarHBondContact O-N 3.46Å; Y400-G402 PolarHBondContact OH-O 3.08Å; Y400-C403 WeakPolarHBondContact CE2-O 3.44Å; Y400-C403 WeakPolarHBondContact OH-CA 3.48Å; Y400-C403 PolarHBondContact OH-N 3.34Å; Y400-C403 PolarHBondContact OH-O 3.42Å; Y400-Y404 PolarHBondContact OH-O 2.97Å; Y400-Y404 VanDerWaalsContact OH-O 3.06Å; Y400-R409 PolarHBondContact OH-NH1 3.38Å
401G89.6Confident90.6Very high2 Ų258.9 Ų58.92%0.02128%0.279CS..  trans-68.6-15.1-173.500000115.4T376 C379 R380 E381T376-G401 WeakPolarHBondContact O-CA 3.29Å; T376-G401 PolarHBondContact O-N 3.48Å; C379-G401 CarbonylContact C-O 3.56Å; C379-G401 WeakPolarHBondContact CB-O 3.46Å; C379-G401 CarbonylContact O-C 3.59Å; C379-G401 WeakPolarHBondContact O-CA 3.32Å; R380-G401 PolarHBondContact N-O 3.03Å; E381-G401 WeakPolarHBondContact CB-O 3.28Å; E381-G401 PolarHBondContact N-O 2.86Å; E381-G401 CarbonylContact O-C 3.57Å; E381-G401 VanDerWaalsContact O-CA 3.26Å; E381-G401 WeakPolarHBondContact O-CA 3.47Å
402G89.1Confident91.2Very high32 Ų3259.8 Ų59.833%0.3329%0.285SS..SBendtrans105.3-15.5177.600000115.7Y400Y400-G402 VanDerWaalsContact CE1-CA 3.45Å; Y400-G402 VanDerWaalsContact CZ-C 3.49Å; Y400-G402 PolarHBondContact O-N 3.46Å; Y400-G402 PolarHBondContact OH-O 3.08Å
403C86.8Confident91.7Very high29 Ų2958.7 Ų58.720%0.19628%0.283CS..SBendtrans-138.6160.8174.568.60000112.7C379 Y400 G405C379-C403 HydrophobicContact CB-CB 3.93Å; C379-C403 WeakPolarHBondContact CB-SG 3.47Å; C379-C403 PolarHBondContact N-SG 3.31Å; C379-C403 VanDerWaalsContact N-SG 3.43Å; C379-C403 WeakPolarHBondContact SG-CB 3.42Å; C379-C403 CovalentContact SG-SG 2.03Å; C379-C403 PolarHBondContact SG-SG 3.46Å; Y400-C403 WeakPolarHBondContact CE2-O 3.44Å; Y400-C403 WeakPolarHBondContact OH-CA 3.48Å; Y400-C403 PolarHBondContact OH-N 3.34Å; Y400-C403 PolarHBondContact OH-O 3.42Å; C403-G405 PolarHBondContact O-N 3.05Å
404Y84.2Confident92Very high144 Ų14460.2 Ų60.257%0.56530%0.295SS*.SBendtrans55.4-130.5-175.9-51.2-71.3000112.5Y400 R409Y400-Y404 PolarHBondContact OH-O 2.97Å; Y400-Y404 VanDerWaalsContact OH-O 3.06Å; Y404-R409 PolarHBondContact O-NH1 2.82Å
405G83.6Confident92.1Very high14 Ų1457 Ų5714%0.14429%0.288CS..  trans68.8-157.3-171.500000112.9C403C403-G405 PolarHBondContact O-N 3.05Å
406N86.9Confident92.2Very high4 Ų457 Ų572%0.02129%0.287CS..  trans-138.2-175.8-172.458.15.1000113.1E372 H373 K375 R409E372-N406 VanDerWaalsContact CB-ND2 3.29Å; E372-N406 WeakPolarHBondContact CB-ND2 3.32Å; E372-N406 WeakPolarHBondContact OE1-CB 3.31Å; E372-N406 PolarHBondContact OE1-ND2 3.05Å; E372-N406 WeakPolarHBondContact OE2-CB 3.3Å; H373-N406 PolarHBondContact O-ND2 3.03Å; K375-N406 HydrophobicContact CD-CB 4.41Å; K375-N406 PolarHBondContact N-OD1 3.23Å; N406-R409 WeakPolarHBondContact O-CB 3.23Å
407E90.4Very high92.3Very high97 Ų9756.6 Ų56.645%0.45329%0.287SS..SBendtrans-83.9-12.7-172.3-60.7-162.9-174.700114R369 R409R369-E407 HydrophobicContact CB-CB 4.38Å; R369-E407 HydrophobicContact CG-CB 3.74Å; R369-E407 WeakPolarHBondContact CG-O 3.09Å; R369-E407 PolarHBondContact NE-O 3.17Å; R369-E407 PolarHBondContact NH2-O 2.77Å; E407-R409 PolarHBondContact O-N 3.05Å
408N92.5Very high92.4Very high0 Ų052.6 Ų52.60%028%0.283CS..SBendtrans-73.550.1169.8-158.80.9000111.9R369 C370 E372 Y387 Y388R369-N408 WeakPolarHBondContact O-CA 3.45Å; R369-N408 WeakPolarHBondContact O-CB 3.42Å; R369-N408 PolarHBondContact O-N 3.3Å; C370-N408 PolarHBondContact O-ND2 3.02Å; E372-N408 HydrophobicContact CB-CB 4.31Å; E372-N408 PolarHBondContact O-ND2 3.25Å; Y387-N408 WeakPolarHBondContact CA-O 3.38Å; Y387-N408 WeakPolarHBondContact CB-O 3.35Å; Y388-N408 PolarHBondContact N-OD1 3.47Å; Y388-N408 PolarHBondContact O-ND2 3Å
409R94.9Very high92.5Very high71 Ų7153.3 Ų53.327%0.26829%0.289SS..  trans-140.9120.9-174-176179.262.3-137-2.8108.6R369 K385 W386 F398 Y400 Y404 N406 E407R369-R409 PolarHBondContact NH2-O 3.49Å; K385-R409 HydrophobicContact CB-CG 3.89Å; K385-R409 HydrophobicContact CD-CG 4.35Å; K385-R409 HydrophobicContact CG-CG 3.88Å; W386-R409 CarbonylContact O-C 3.51Å; W386-R409 WeakPolarHBondContact O-CA 3.37Å; F398-R409 HydrophobicContact CE1-CB 4.46Å; F398-R409 HydrophobicContact CE1-CG 4.16Å; F398-R409 HydrophobicContact CZ-CB 4.21Å; F398-R409 HydrophobicContact CZ-CG 3.87Å; Y400-R409 PolarHBondContact OH-NH1 3.38Å; Y404-R409 PolarHBondContact O-NH1 2.82Å; N406-R409 WeakPolarHBondContact O-CB 3.23Å; E407-R409 PolarHBondContact O-N 3.05Å
410F96.3Very high92.7Very high10 Ų1049 Ų494%0.04427%0.266CS..BIsolated β-bridgetrans-132.4151.3-175.2-58.3-94.1000110.2R369 W386 A415 C416 T419R369-F410 VanDerWaalsContact NH2-CE1 3.28Å; W386-F410 HydrophobicContact CB-CB 4.25Å; W386-F410 PolarHBondContact N-O 3.17Å; W386-F410 PolarHBondContact O-N 2.92Å; F410-A415 HydrophobicContact CD1-CB 4.33Å; F410-C416 HydrophobicContact CB-CB 3.77Å; F410-C416 HydrophobicContact CD1-CB 4.21Å; F410-C416 HydrophobicContact CD2-CB 3.57Å; F410-C416 HydrophobicContact CE2-CB 4.18Å; F410-C416 HydrophobicContact CG-CB 3.59Å; F410-T419 HydrophobicContact CE1-CG2 3.97Å; F410-T419 HydrophobicContact CZ-CG2 4.03Å
411D96.4Very high92.6Very high117 Ų11754.3 Ų54.363%0.62629%0.29SS*.SBendtrans-79.4-25.7178.1-62.7-51.9000112.8K385K385-D411 IonicContact NZ-OD1 2.65Å; K385-D411 PolarHBondContact NZ-OD1 2.94Å
412T97.4Very high92.6Very high70 Ų7059.9 Ų59.943%0.42932%0.318SS..SBendtrans-136.3153.7-17764.30000112.3D414 A415 C416T412-D414 VanDerWaalsContact C-N 3.35Å; T412-A415 PolarHBondContact O-N 3.11Å; T412-A415 VanDerWaalsContact OG1-CB 3.28Å; T412-A415 WeakPolarHBondContact OG1-CB 3.03Å; T412-A415 PolarHBondContact OG1-N 3.17Å; T412-C416 PolarHBondContact O-N 2.9Å; T412-C416 VanDerWaalsContact O-N 3.17Å
413E96.7Very high92.7Very high76 Ų7658.4 Ų58.436%0.35530%0.303SS..Hα-helixtrans-60.5-43.4174.8-168.4171.7-173.300111.2W386 C395 A415 C416 M417W386-E413 HydrophobicContact CD2-CB 3.88Å; W386-E413 HydrophobicContact CD2-CG 4.44Å; W386-E413 HydrophobicContact CE3-CB 3.84Å; W386-E413 HydrophobicContact CE3-CG 3.88Å; W386-E413 HydrophobicContact CH2-CB 3.75Å; W386-E413 HydrophobicContact CH2-CG 3.92Å; W386-E413 WeakPolarHBondContact CH2-OE2 3.41Å; W386-E413 HydrophobicContact CZ2-CB 3.82Å; W386-E413 HydrophobicContact CZ2-CG 4.5Å; W386-E413 HydrophobicContact CZ3-CB 3.76Å; W386-E413 VanDerWaalsContact CZ3-CD 3.47Å; W386-E413 HydrophobicContact CZ3-CG 3.59Å; C395-E413 HydrophobicContact CB-CG 4.2Å; E413-A415 PolarHBondContact O-N 3Å; E413-C416 WeakPolarHBondContact O-CB 3.42Å; E413-C416 PolarHBondContact O-N 2.96Å; E413-M417 HydrophobicContact CG-CG 4.24Å; E413-M417 WeakPolarHBondContact O-CB 3.49Å; E413-M417 WeakPolarHBondContact O-CG 3.5Å; E413-M417 PolarHBondContact O-N 2.77Å
414D96.7Very high92.8Very high132 Ų13258.7 Ų58.771%0.70630%0.304SS*.Hα-helixtrans-62-42179.8-67.5-43000112.9T412 S418T412-D414 VanDerWaalsContact C-N 3.35Å; D414-S418 WeakPolarHBondContact O-CB 3.35Å; D414-S418 PolarHBondContact O-N 2.79Å; D414-S418 PolarHBondContact O-OG 2.94Å
415A96.8Very high92.9Very high36 Ų3656.6 Ų56.630%0.29830%0.299SS..Hα-helixtrans-64.2-45.3176.100000110.7F410 T412 E413 S418 T419F410-A415 HydrophobicContact CD1-CB 4.33Å; T412-A415 PolarHBondContact O-N 3.11Å; T412-A415 VanDerWaalsContact OG1-CB 3.28Å; T412-A415 WeakPolarHBondContact OG1-CB 3.03Å; T412-A415 PolarHBondContact OG1-N 3.17Å; E413-A415 PolarHBondContact O-N 3Å; A415-S418 PolarHBondContact O-OG 3.19Å; A415-S418 VanDerWaalsContact O-OG 3.09Å; A415-T419 WeakPolarHBondContact O-CB 3.49Å; A415-T419 PolarHBondContact O-N 3.4Å; A415-T419 PolarHBondContact O-OG1 2.74Å
416C96.4Very high92.9Very high0 Ų061.1 Ų61.10%032%0.315CS..Hα-helixtrans-59.2-51.7176177.60000112.2W386 Y387 C395 F410 T412 E413 T419 C420W386-C416 HydrophobicContact CB-CB 4.2Å; Y387-C416 VanDerWaalsContact C-SG 3.52Å; C395-C416 HydrophobicContact CB-CB 3.83Å; C395-C416 WeakPolarHBondContact CB-SG 3.48Å; C395-C416 WeakPolarHBondContact SG-CB 3.39Å; C395-C416 CovalentContact SG-SG 2.02Å; C395-C416 PolarHBondContact SG-SG 2.89Å; F410-C416 HydrophobicContact CB-CB 3.77Å; F410-C416 HydrophobicContact CD1-CB 4.21Å; F410-C416 HydrophobicContact CD2-CB 3.57Å; F410-C416 HydrophobicContact CE2-CB 4.18Å; F410-C416 HydrophobicContact CG-CB 3.59Å; T412-C416 PolarHBondContact O-N 2.9Å; T412-C416 VanDerWaalsContact O-N 3.17Å; E413-C416 WeakPolarHBondContact O-CB 3.42Å; E413-C416 PolarHBondContact O-N 2.96Å; C416-T419 PolarHBondContact O-N 3.43Å; C416-C420 WeakPolarHBondContact O-CB 3.45Å; C416-C420 PolarHBondContact O-N 2.97Å
417M95.7Very high92.8Very high61 Ų6161.1 Ų61.130%0.332%0.315SS..Hα-helixtrans-66.8-41.8-178.7-71-61.3-63.300111.9Y388 C395 E413 T419 C420 K421Y388-M417 HydrophobicContact CD2-SD 4.47Å; Y388-M417 HydrophobicContact CE2-SD 4.38Å; C395-M417 HydrophobicContact CB-CG 4.15Å; C395-M417 HydrophobicContact CB-SD 3.95Å; C395-M417 PolarHBondContact N-SD 3.18Å; C395-M417 VanDerWaalsContact N-SD 3.4Å; C395-M417 PolarHBondContact SG-N 3.16Å; C395-M417 PolarHBondContact SG-SD 2.87Å; E413-M417 HydrophobicContact CG-CG 4.24Å; E413-M417 WeakPolarHBondContact O-CB 3.49Å; E413-M417 WeakPolarHBondContact O-CG 3.5Å; E413-M417 PolarHBondContact O-N 2.77Å; M417-T419 VanDerWaalsContact C-N 3.33Å; M417-T419 PolarHBondContact O-N 3.4Å; M417-C420 PolarHBondContact O-N 3.41Å; M417-K421 VanDerWaalsContact O-CB 3.24Å; M417-K421 WeakPolarHBondContact O-CB 3.43Å; M417-K421 PolarHBondContact O-N 3.4Å; M417-K421 VanDerWaalsContact O-N 3.12Å
418S94.8Very high92.4Very high72 Ų7257 Ų5750%0.50330%0.296SS..Hα-helixtrans-65.5-35.5179620000112.7D414 A415D414-S418 WeakPolarHBondContact O-CB 3.35Å; D414-S418 PolarHBondContact O-N 2.79Å; D414-S418 PolarHBondContact O-OG 2.94Å; A415-S418 PolarHBondContact O-OG 3.19Å; A415-S418 VanDerWaalsContact O-OG 3.09Å
419T94Very high91.6Very high38 Ų3859 Ų5923%0.23331%0.305CS..Hα-helixtrans-74.5-44.3174.6-57.70000112.7Q366 F410 A415 C416 M417Q366-T419 PolarHBondContact NE2-O 3Å; F410-T419 HydrophobicContact CE1-CG2 3.97Å; F410-T419 HydrophobicContact CZ-CG2 4.03Å; A415-T419 WeakPolarHBondContact O-CB 3.49Å; A415-T419 PolarHBondContact O-N 3.4Å; A415-T419 PolarHBondContact O-OG1 2.74Å; C416-T419 PolarHBondContact O-N 3.43Å; M417-T419 VanDerWaalsContact C-N 3.33Å; M417-T419 PolarHBondContact O-N 3.4Å
420C94.8Very high90.2Very high0 Ų058.6 Ų58.60%031%0.306CS..Hα-helixtrans-102.5-6.9-165.5-63.70000116.7C370 Y388 C416 M417 L422 V423C370-C420 HydrophobicContact CB-CB 3.64Å; C370-C420 WeakPolarHBondContact CB-SG 3.4Å; C370-C420 WeakPolarHBondContact SG-CA 3.47Å; C370-C420 WeakPolarHBondContact SG-CB 3.29Å; C370-C420 CovalentContact SG-SG 2.03Å; C370-C420 PolarHBondContact SG-SG 3Å; Y388-C420 HydrophobicContact CD1-CB 3.5Å; Y388-C420 HydrophobicContact CD2-CB 3.4Å; Y388-C420 VanDerWaalsContact CD2-CB 3.4Å; Y388-C420 HydrophobicContact CE1-CB 3.91Å; Y388-C420 WeakPolarHBondContact CE1-O 3.36Å; Y388-C420 HydrophobicContact CE2-CB 3.83Å; Y388-C420 HydrophobicContact CG-CB 3.2Å; Y388-C420 VanDerWaalsContact CZ-O 3.27Å; Y388-C420 PolarHBondContact OH-O 3.18Å; C416-C420 WeakPolarHBondContact O-CB 3.45Å; C416-C420 PolarHBondContact O-N 2.97Å; M417-C420 PolarHBondContact O-N 3.41Å; C420-L422 PolarHBondContact O-N 3.3Å; C420-V423 WeakPolarHBondContact O-CB 3.15Å; C420-V423 WeakPolarHBondContact O-CG2 3.42Å; C420-V423 PolarHBondContact O-N 2.69Å
421K90.9Very high88Confident135 Ų13559 Ų5959%0.58731%0.308SS*.THydrogen-bonded Turntrans-50.9-11.9-17662-179.8179.3-177.90119M417M417-K421 VanDerWaalsContact O-CB 3.24Å; M417-K421 WeakPolarHBondContact O-CB 3.43Å; M417-K421 PolarHBondContact O-N 3.4Å; M417-K421 VanDerWaalsContact O-N 3.12Å
422L90.2Very high85.2Confident119 Ų11957.8 Ų57.862%0.62331%0.305SS*.THydrogen-bonded Turntrans-100.9-2.6179-62.1-177.5000113.3C420C420-L422 PolarHBondContact O-N 3.3Å
423V90.8Very high82.1Confident1 Ų159.4 Ų59.41%0.00631%0.311CS..  trans-98.1134.8-173.6-172.10000109.2K367 C370 T371 Y388 P390 C420 D427K367-V423 HydrophobicContact CG-CG2 4.06Å; C370-V423 HydrophobicContact CB-CB 4.08Å; C370-V423 HydrophobicContact CB-CG1 4.09Å; C370-V423 HydrophobicContact CB-CG2 3.79Å; T371-V423 HydrophobicContact CG2-CG1 3.61Å; Y388-V423 HydrophobicContact CE1-CB 3.98Å; Y388-V423 WeakPolarHBondContact CE1-O 3.46Å; Y388-V423 PolarHBondContact OH-O 2.84Å; P390-V423 HydrophobicContact CB-CG1 4.21Å; P390-V423 HydrophobicContact CG-CG1 4.14Å; C420-V423 WeakPolarHBondContact O-CB 3.15Å; C420-V423 WeakPolarHBondContact O-CG2 3.42Å; C420-V423 PolarHBondContact O-N 2.69Å; V423-D427 HydrophobicContact CG1-CB 4.19Å
424T89.4Confident79Confident35 Ų3564.9 Ų64.922%0.21533%0.328CS..  trans-133.5168.8-170.765.10000112P390 K426 D427P390-T424 CarbonylContact O-C 3.57Å; T424-K426 PolarHBondContact O-N 3.26Å; T424-K426 PolarHBondContact OG1-N 3.04Å; T424-D427 PolarHBondContact N-OD2 3.42Å; T424-D427 WeakPolarHBondContact O-CB 3.21Å; T424-D427 PolarHBondContact O-N 3.35Å; T424-D427 PolarHBondContact OG1-OD2 3.42Å
425E84.7Confident75.9Confident101 Ų10168.6 Ų68.647%0.47233%0.334SS..G310 helixtrans-44-28167.471.8-174.5-178.200114.2R40 P390 D427 I428R40-E425 PolarHBondContact NH1-O 2.93Å; P390-E425 PolarHBondContact O-N 2.95Å; E425-D427 PolarHBondContact O-N 2.89Å; E425-I428 PolarHBondContact O-N 2.83Å
426K84.5Confident72.7Confident108 Ų10872.3 Ų72.347%0.4735%0.345SS..G310 helixtrans-77.5-12-179.2-62177-178.1169.90112.8R113 T424R113-K426 VanDerWaalsContact CD-O 3.28Å; R113-K426 WeakPolarHBondContact CD-O 3.18Å; R113-K426 PolarHBondContact NE-O 3.36Å; R113-K426 PolarHBondContact NH1-O 3.15Å; T424-K426 PolarHBondContact O-N 3.26Å; T424-K426 PolarHBondContact OG1-N 3.04Å
427D85.4Confident69.7Low5 Ų582.2 Ų82.23%0.02738%0.384CS..G310 helixtrans-104.2-7.5178.8-49.4-69.5000112.2F43 R113 K367 T371 V423 T424 E425F43-D427 WeakPolarHBondContact CE1-O 3.43Å; R113-D427 WeakPolarHBondContact CD-OD1 3.17Å; R113-D427 IonicContact CZ-OD1 3.95Å; R113-D427 IonicContact NE-OD1 3.88Å; R113-D427 IonicContact NH1-OD1 2.69Å; R113-D427 PolarHBondContact NH1-OD1 2.87Å; K367-D427 HydrophobicContact CD-CB 4.36Å; K367-D427 IonicContact NZ-OD1 2.77Å; K367-D427 PolarHBondContact NZ-OD1 3.28Å; K367-D427 IonicContact NZ-OD2 3.95Å; T371-D427 HydrophobicContact CG2-CB 4.27Å; T371-D427 WeakPolarHBondContact CG2-O 3.49Å; V423-D427 HydrophobicContact CG1-CB 4.19Å; T424-D427 PolarHBondContact N-OD2 3.42Å; T424-D427 WeakPolarHBondContact O-CB 3.21Å; T424-D427 PolarHBondContact O-N 3.35Å; T424-D427 PolarHBondContact OG1-OD2 3.42Å; E425-D427 PolarHBondContact O-N 2.89Å
428I80.4Confident66.5Low11 Ų1186.7 Ų86.76%0.05640%0.404CS..SBendtrans-77.3136.4172.3-48.6178.6000110.1R40 F43 P390 V391 E425 E430R40-I428 PolarHBondContact NH1-O 2.82Å; F43-I428 VanDerWaalsContact CZ-O 3.29Å; F43-I428 WeakPolarHBondContact CZ-O 3.27Å; P390-I428 HydrophobicContact CB-CD1 3.92Å; P390-I428 HydrophobicContact CB-CG1 3.94Å; P390-I428 HydrophobicContact CG-CD1 4.06Å; P390-I428 HydrophobicContact CG-CG1 3.98Å; V391-I428 HydrophobicContact CG2-CD1 3.6Å; E425-I428 PolarHBondContact O-N 2.83Å; I428-E430 HydrophobicContact CG2-CB 4.26Å; I428-E430 HydrophobicContact CG2-CG 3.77Å; I428-E430 PolarHBondContact O-N 2.68Å
429F75.6Confident63.4Low41 Ų4189.8 Ų89.818%0.1842%0.415CS..  trans-86.156.7168.3-171.2-103.6000111.3R40 F43 F111 N119 I121 I431R40-F429 HydrophobicContact CB-CD2 3.97Å; R40-F429 HydrophobicContact CB-CE2 3.88Å; F43-F429 HydrophobicContact CB-CD2 3.7Å; F43-F429 HydrophobicContact CB-CE2 3.94Å; F43-F429 HydrophobicContact CD1-CB 3.84Å; F43-F429 AromaticContact CD1-CD2 3.61Å; F43-F429 HydrophobicContact CD1-CD2 3.61Å; F43-F429 HydrophobicContact CD1-CG 4.17Å; F43-F429 HydrophobicContact CD2-CD2 4.15Å; F43-F429 HydrophobicContact CE1-CB 3.85Å; F43-F429 HydrophobicContact CE1-CD2 4.25Å; F43-F429 AromaticContact CG-CD2 3.56Å; F43-F429 HydrophobicContact CG-CD2 3.56Å; F43-F429 HydrophobicContact CG-CE2 4.24Å; F111-F429 HydrophobicContact CB-CB 3.74Å; F111-F429 HydrophobicContact CB-CD1 3.79Å; F111-F429 HydrophobicContact CB-CD2 3.63Å; F111-F429 HydrophobicContact CB-CE1 4.3Å; F111-F429 HydrophobicContact CB-CE2 4.14Å; F111-F429 HydrophobicContact CB-CG 3.42Å; F111-F429 VanDerWaalsContact CB-CG 3.42Å; F111-F429 HydrophobicContact CB-CZ 4.44Å; F111-F429 HydrophobicContact CD1-CE2 4.36Å; F111-F429 HydrophobicContact CD1-CZ 4.38Å; F111-F429 AromaticContact CD2-CD1 3.34Å; F111-F429 HydrophobicContact CD2-CD1 3.34Å; F111-F429 HydrophobicContact CD2-CD2 4.3Å; F111-F429 AromaticContact CD2-CE1 3.2Å; F111-F429 HydrophobicContact CD2-CE1 3.2Å; F111-F429 HydrophobicContact CD2-CE2 4.17Å; F111-F429 AromaticContact CD2-CG 3.91Å; F111-F429 HydrophobicContact CD2-CG 3.91Å; F111-F429 AromaticContact CD2-CZ 3.64Å; F111-F429 HydrophobicContact CD2-CZ 3.64Å; F111-F429 HydrophobicContact CE2-CD1 4.13Å; F111-F429 AromaticContact CE2-CE1 3.52Å; F111-F429 HydrophobicContact CE2-CE1 3.52Å; F111-F429 AromaticContact CE2-CZ 3.81Å; F111-F429 HydrophobicContact CE2-CZ 3.81Å; F111-F429 AromaticContact CG-CD1 3.83Å; F111-F429 HydrophobicContact CG-CD1 3.83Å; F111-F429 AromaticContact CG-CD2 3.98Å; F111-F429 HydrophobicContact CG-CD2 3.98Å; F111-F429 AromaticContact CG-CE1 3.85Å; F111-F429 HydrophobicContact CG-CE1 3.85Å; F111-F429 AromaticContact CG-CE2 3.98Å; F111-F429 HydrophobicContact CG-CE2 3.98Å; F111-F429 AromaticContact CG-CG 3.9Å; F111-F429 HydrophobicContact CG-CG 3.9Å; F111-F429 AromaticContact CG-CZ 3.91Å; F111-F429 HydrophobicContact CG-CZ 3.91Å; F111-F429 HydrophobicContact CZ-CE1 4.42Å; F111-F429 HydrophobicContact CZ-CZ 4.29Å; N119-F429 VanDerWaalsContact OD1-CE2 3.3Å; N119-F429 WeakPolarHBondContact OD1-CE2 3.3Å; N119-F429 VanDerWaalsContact OD1-CZ 3.23Å; N119-F429 WeakPolarHBondContact OD1-CZ 3.37Å; I121-F429 HydrophobicContact CD1-CE1 3.74Å; I121-F429 HydrophobicContact CD1-CZ 3.89Å; F429-I431 HydrophobicContact CE1-CD1 3.89Å; F429-I431 HydrophobicContact CE1-CG1 3.88Å; F429-I431 HydrophobicContact CZ-CD1 3.94Å; F429-I431 HydrophobicContact CZ-CG1 3.92Å
430E65.5Low60.7Low62 Ų6292.4 Ų92.429%0.2943%0.431SS..  trans-81.5116.1164.6-85.9166.4-145.700107.6I428 T432I428-E430 HydrophobicContact CG2-CB 4.26Å; I428-E430 HydrophobicContact CG2-CG 3.77Å; I428-E430 PolarHBondContact O-N 2.68Å; E430-T432 PolarHBondContact O-N 3.38Å
431I51.5Low58.1Low20 Ų2098.7 Ų98.710%0.10347%0.465CS..  trans-7680.3163.1-48.8172.3000106I121 Y126 L130 F429 N433I121-I431 HydrophobicContact CD1-CD1 4.01Å; Y126-I431 HydrophobicContact CD2-CD1 4.1Å; Y126-I431 HydrophobicContact CE2-CB 3.97Å; Y126-I431 HydrophobicContact CE2-CD1 4.14Å; Y126-I431 HydrophobicContact CE2-CG2 3.83Å; L130-I431 HydrophobicContact CD1-CB 3.9Å; L130-I431 HydrophobicContact CD1-CG1 4.5Å; F429-I431 HydrophobicContact CE1-CD1 3.89Å; F429-I431 HydrophobicContact CE1-CG1 3.88Å; F429-I431 HydrophobicContact CZ-CD1 3.94Å; F429-I431 HydrophobicContact CZ-CG1 3.92Å; I431-N433 PolarHBondContact O-N 3.02Å
432T36Very low55.8Low91 Ų9194.6 Ų94.656%0.55846%0.461SS*.  trans-57.5107.5167.741.20000108E430 R434E430-T432 PolarHBondContact O-N 3.38Å; T432-R434 PolarHBondContact O-N 3.48Å
433N32.4Very low53.8Low103 Ų10395.1 Ų95.155%0.55146%0.46SS*.  trans-40.8115.1157-135.1-43.5000107.3Y126 I431 Y435Y126-N433 PolarHBondContact OH-ND2 2.98Å; I431-N433 PolarHBondContact O-N 3.02Å; N433-Y435 VanDerWaalsContact C-N 3.26Å; N433-Y435 PolarHBondContact O-N 3.13Å
434R33.4Very low52Low191 Ų19199.2 Ų99.272%0.72149%0.485SS*.  trans-69.285.3-172.9-77.7-170.9-175.2-169.76.8109.6T432 E436T432-R434 PolarHBondContact O-N 3.48Å; R434-E436 HydrophobicContact CB-CG 4.33Å; R434-E436 WeakPolarHBondContact CD-OE1 3.23Å; R434-E436 IonicContact CZ-OE1 3.34Å; R434-E436 IonicContact NE-OE1 2.7Å; R434-E436 IonicContact NH1-OE1 3.93Å; R434-E436 PolarHBondContact NH1-OE1 3.14Å; R434-E436 PolarHBondContact O-N 3.06Å
435Y30.9Very low50.2Low211 Ų21199.2 Ų99.283%0.82749%0.492SS*.  -65.282.4129.2-66.3-68.9000106.6N433 Y437N433-Y435 VanDerWaalsContact C-N 3.26Å; N433-Y435 PolarHBondContact O-N 3.13Å; Y435-Y437 VanDerWaalsContact C-N 3.26Å; Y435-Y437 PolarHBondContact O-N 2.96Å
436E29.7Very low49Very low114 Ų114100 Ų10053%0.53350%0.498SS..  trans-53.2106.6150.4-90172.1-163.900105.6R434 Q438R434-E436 HydrophobicContact CB-CG 4.33Å; R434-E436 WeakPolarHBondContact CD-OE1 3.23Å; R434-E436 IonicContact CZ-OE1 3.34Å; R434-E436 IonicContact NE-OE1 2.7Å; R434-E436 IonicContact NH1-OE1 3.93Å; R434-E436 PolarHBondContact NH1-OE1 3.14Å; R434-E436 PolarHBondContact O-N 3.06Å; E436-Q438 PolarHBondContact O-N 3.2Å
437Y33Very low47.8Very low208 Ų208100 Ų10082%0.81650%0.503SS*.  trans-64.782.7153-164.4-84.9000105Y435 D439Y435-Y437 VanDerWaalsContact C-N 3.26Å; Y435-Y437 PolarHBondContact O-N 2.96Å; Y437-D439 PolarHBondContact O-N 3.43Å
438Q28Very low46.9Very low155 Ų155103.4 Ų103.472%0.72452%0.523SS*.  trans-64.8105.3-174.4-170.2172.88.600106.4E436 T440E436-Q438 PolarHBondContact O-N 3.2Å; Q438-T440 PolarHBondContact O-N 2.89Å
439D30Very low46.4Very low136 Ų136107.7 Ų107.773%0.72755%0.545SS*.  trans-52.6135.6-176.2-165.57000109.3Y437 D441Y437-D439 PolarHBondContact O-N 3.43Å; D439-D441 VanDerWaalsContact C-N 3.33Å; D439-D441 PolarHBondContact O-N 3.33Å
440T37.9Very low46.3Very low93 Ų93108.5 Ų108.557%0.57156%0.559SS**SBendtrans-79.873.7-150.9490000113.1Q438Q438-T440 PolarHBondContact O-N 2.89Å
441D39.8Very low46.8Very low132 Ų132108.3 Ų108.371%0.70657%0.568SS**  trans-108.7-5.8175.4-147.416.3000113.6D439D439-D441 VanDerWaalsContact C-N 3.33Å; D439-D441 PolarHBondContact O-N 3.33Å
442G42.3Very low48.2Very low50 Ų50112.5 Ų112.552%0.51559%0.59SS.*Hα-helixtrans-73.1-26.3171.900000114.4G445 I446G442-G445 PolarHBondContact O-N 2.89Å; G442-I446 WeakPolarHBondContact O-CG1 3.32Å; G442-I446 PolarHBondContact O-N 2.88Å
443H48.5Very low50.4Low130 Ų130113.2 Ų113.260%0.60259%0.59SS**Hα-helixtrans-72.2-32.5-176-91.560.4000113.1I446 I447H443-I446 PolarHBondContact O-N 3.37Å; H443-I447 WeakPolarHBondContact O-CB 3.5Å; H443-I447 WeakPolarHBondContact O-CD1 3.37Å; H443-I447 WeakPolarHBondContact O-CG1 3.48Å; H443-I447 PolarHBondContact O-N 3.43Å
444V53.2Low52.9Low87 Ų87109.7 Ų109.753%0.52758%0.578SS.*Hα-helixtrans-64.4-44.6176.2-175.70000110.2I447 V448V444-I447 PolarHBondContact O-N 3.41Å; V444-V448 HydrophobicContact CG1-CG2 4.4Å; V444-V448 WeakPolarHBondContact O-CB 3.36Å; V444-V448 VanDerWaalsContact O-CG2 3.25Å; V444-V448 WeakPolarHBondContact O-CG2 3.43Å; V444-V448 PolarHBondContact O-N 2.91Å
445G52.2Low55.5Low35 Ų35105.5 Ų105.536%0.36157%0.57SS.*Hα-helixtrans-60.4-47.3176.800000113.1G442 V448 I449G442-G445 PolarHBondContact O-N 2.89Å; G445-V448 PolarHBondContact O-N 3.01Å; G445-I449 WeakPolarHBondContact O-CB 3.29Å; G445-I449 VanDerWaalsContact O-CG1 3.27Å; G445-I449 WeakPolarHBondContact O-CG1 3.38Å; G445-I449 PolarHBondContact O-N 3.44Å
446I58.3Low58Low116 Ų11698 Ų9860%0.59555%0.551SS**Hα-helixtrans-66.2-42179.8-65.4172000111.3G442 H443 I449 A450G442-I446 WeakPolarHBondContact O-CG1 3.32Å; G442-I446 PolarHBondContact O-N 2.88Å; H443-I446 PolarHBondContact O-N 3.37Å; I446-I449 PolarHBondContact O-N 2.96Å; I446-A450 VanDerWaalsContact O-CB 3.25Å; I446-A450 WeakPolarHBondContact O-CB 3.35Å; I446-A450 PolarHBondContact O-N 3.15Å
447I59.7Low60.9Low110 Ų11097.5 Ų97.556%0.56455%0.551SS**Hα-helixtrans-64.4-41.7177.1-69.4166.7000110.9H443 V444 A450 A451H443-I447 WeakPolarHBondContact O-CB 3.5Å; H443-I447 WeakPolarHBondContact O-CD1 3.37Å; H443-I447 WeakPolarHBondContact O-CG1 3.48Å; H443-I447 PolarHBondContact O-N 3.43Å; V444-I447 PolarHBondContact O-N 3.41Å; I447-A450 PolarHBondContact O-N 3.03Å; I447-A451 VanDerWaalsContact O-CB 3.24Å; I447-A451 WeakPolarHBondContact O-CB 3.38Å; I447-A451 PolarHBondContact O-N 3.1Å
448V65.9Low63.5Low75 Ų7592.6 Ų92.646%0.45554%0.538SS..Hα-helixtrans-65.6-43.8176.7169.60000111.4V444 G445 A451 L452V444-V448 HydrophobicContact CG1-CG2 4.4Å; V444-V448 WeakPolarHBondContact O-CB 3.36Å; V444-V448 VanDerWaalsContact O-CG2 3.25Å; V444-V448 WeakPolarHBondContact O-CG2 3.43Å; V444-V448 PolarHBondContact O-N 2.91Å; G445-V448 PolarHBondContact O-N 3.01Å; V448-A451 PolarHBondContact O-N 3.09Å; V448-L452 HydrophobicContact CG1-CD1 3.87Å; V448-L452 HydrophobicContact CG1-CG 4.43Å; V448-L452 WeakPolarHBondContact O-CB 3.45Å; V448-L452 VanDerWaalsContact O-CG 3.25Å; V448-L452 WeakPolarHBondContact O-CG 3.1Å; V448-L452 PolarHBondContact O-N 3.1Å
449I70.4Confident66.4Low102 Ų10290 Ų9052%0.52353%0.528SS..Hα-helixtrans-64.8-43.8177-68.8166000110.9G445 I446 A451 L452 L453G445-I449 WeakPolarHBondContact O-CB 3.29Å; G445-I449 VanDerWaalsContact O-CG1 3.27Å; G445-I449 WeakPolarHBondContact O-CG1 3.38Å; G445-I449 PolarHBondContact O-N 3.44Å; I446-I449 PolarHBondContact O-N 2.96Å; I449-A451 PolarHBondContact O-N 2.74Å; I449-L452 PolarHBondContact O-N 3.23Å; I449-L453 HydrophobicContact CG2-CD1 3.88Å; I449-L453 HydrophobicContact CG2-CG 4.39Å; I449-L453 WeakPolarHBondContact O-CB 3.37Å; I449-L453 WeakPolarHBondContact O-CG 3.3Å; I449-L453 PolarHBondContact O-N 2.91Å
450A74.1Confident69.2Low58 Ų5888.6 Ų88.648%0.47952%0.52SS..Hα-helixtrans-63.5-40.5176.600000112.1I446 I447 G454I446-A450 VanDerWaalsContact O-CB 3.25Å; I446-A450 WeakPolarHBondContact O-CB 3.35Å; I446-A450 PolarHBondContact O-N 3.15Å; I447-A450 PolarHBondContact O-N 3.03Å; A450-G454 PolarHBondContact O-N 3.21Å
451A75.8Confident71.6Confident57 Ų5789 Ų8947%0.47152%0.518SS..Hα-helixtrans-65.1-42.2175.200000112.1I447 V448 I449 G454 L455I447-A451 VanDerWaalsContact O-CB 3.24Å; I447-A451 WeakPolarHBondContact O-CB 3.38Å; I447-A451 PolarHBondContact O-N 3.1Å; V448-A451 PolarHBondContact O-N 3.09Å; I449-A451 PolarHBondContact O-N 2.74Å; A451-G454 PolarHBondContact O-N 3.45Å; A451-L455 WeakPolarHBondContact O-CB 3.32Å; A451-L455 PolarHBondContact O-N 3.18Å
452L79.8Confident74Confident109 Ų10987.2 Ų87.257%0.57151%0.512SS*.Hα-helixtrans-66.4-42176.5-72.8170.6000112.3V448 I449 L455 A456V448-L452 HydrophobicContact CG1-CD1 3.87Å; V448-L452 HydrophobicContact CG1-CG 4.43Å; V448-L452 WeakPolarHBondContact O-CB 3.45Å; V448-L452 VanDerWaalsContact O-CG 3.25Å; V448-L452 WeakPolarHBondContact O-CG 3.1Å; V448-L452 PolarHBondContact O-N 3.1Å; I449-L452 PolarHBondContact O-N 3.23Å; L452-L455 PolarHBondContact O-N 3.45Å; L452-A456 WeakPolarHBondContact O-CB 3.37Å; L452-A456 PolarHBondContact O-N 3.38Å
453L82.4Confident76.1Confident105 Ų10588.5 Ų88.555%0.5551%0.51SS..Hα-helixtrans-65.2-41.4174-71.8170.9000111.5I449 A456 I457I449-L453 HydrophobicContact CG2-CD1 3.88Å; I449-L453 HydrophobicContact CG2-CG 4.39Å; I449-L453 WeakPolarHBondContact O-CB 3.37Å; I449-L453 WeakPolarHBondContact O-CG 3.3Å; I449-L453 PolarHBondContact O-N 2.91Å; L453-A456 PolarHBondContact O-N 2.94Å; L453-I457 WeakPolarHBondContact O-CB 3.1Å; L453-I457 VanDerWaalsContact O-CG1 3.26Å; L453-I457 WeakPolarHBondContact O-CG1 3.28Å; L453-I457 PolarHBondContact O-N 3.05Å
454G85.2Confident77.9Confident30 Ų3087 Ų8731%0.30951%0.505SS..Hα-helixtrans-59.1-46.7173.200000112.5A450 A451 I457 I458A450-G454 PolarHBondContact O-N 3.21Å; A451-G454 PolarHBondContact O-N 3.45Å; G454-I457 PolarHBondContact O-N 3.23Å; G454-I458 VanDerWaalsContact O-CG1 3.28Å; G454-I458 WeakPolarHBondContact O-CG1 3.24Å; G454-I458 PolarHBondContact O-N 3.12Å
455L88.3Confident79.3Confident102 Ų10286.9 Ų86.953%0.53451%0.507SS..Hα-helixtrans-60.8-44.7174.6-109.4161.6000112.1A451 L452 I457 I458 I459A451-L455 WeakPolarHBondContact O-CB 3.32Å; A451-L455 PolarHBondContact O-N 3.18Å; L452-L455 PolarHBondContact O-N 3.45Å; L455-I457 PolarHBondContact O-N 3.25Å; L455-I458 PolarHBondContact O-N 2.76Å; L455-I459 HydrophobicContact CD2-CD1 4.3Å; L455-I459 VanDerWaalsContact O-CG1 3.26Å; L455-I459 WeakPolarHBondContact O-CG1 3.11Å; L455-I459 PolarHBondContact O-N 3.26Å
456A84Confident80.7Confident54 Ų5492.3 Ų92.345%0.44652%0.518SS..Hα-helixtrans-61.6-43.5177.300000112L452 L453 I459 L460L452-A456 WeakPolarHBondContact O-CB 3.37Å; L452-A456 PolarHBondContact O-N 3.38Å; L453-A456 PolarHBondContact O-N 2.94Å; A456-I459 PolarHBondContact O-N 2.04Å; A456-L460 WeakPolarHBondContact O-CB 3.05Å; A456-L460 PolarHBondContact O-N 2.88Å
457I89.2Confident81.7Confident104 Ų10490.1 Ų90.153%0.53351%0.512SS..Hα-helixtrans-64.2-43.7176.4-69164.3000110.9L453 G454 L455 I459 L460 L461L453-I457 WeakPolarHBondContact O-CB 3.1Å; L453-I457 VanDerWaalsContact O-CG1 3.26Å; L453-I457 WeakPolarHBondContact O-CG1 3.28Å; L453-I457 PolarHBondContact O-N 3.05Å; G454-I457 PolarHBondContact O-N 3.23Å; L455-I457 PolarHBondContact O-N 3.25Å; I457-I459 PolarHBondContact O-N 3.48Å; I457-L460 PolarHBondContact O-N 2.61Å; I457-L461 HydrophobicContact CG2-CD1 3.99Å; I457-L461 HydrophobicContact CG2-CG 4.36Å; I457-L461 WeakPolarHBondContact O-CB 3.39Å; I457-L461 WeakPolarHBondContact O-CG 3.17Å; I457-L461 PolarHBondContact O-N 2.75Å
458I89Confident82.5Confident104 Ų10491.4 Ų91.453%0.53351%0.514SS..Hα-helixtrans-61.7-45.1176.9-70.1165.2000110.8G454 L455 L460 L461 V462G454-I458 VanDerWaalsContact O-CG1 3.28Å; G454-I458 WeakPolarHBondContact O-CG1 3.24Å; G454-I458 PolarHBondContact O-N 3.12Å; L455-I458 PolarHBondContact O-N 2.76Å; I458-L460 VanDerWaalsContact C-N 3.32Å; I458-L460 PolarHBondContact O-N 2.74Å; I458-L461 PolarHBondContact O-N 3.12Å; I458-V462 HydrophobicContact CG2-CG2 4.48Å; I458-V462 VanDerWaalsContact O-CG2 3.32Å; I458-V462 WeakPolarHBondContact O-CG2 3.48Å; I458-V462 PolarHBondContact O-N 2.85Å
459I88.6Confident82.9Confident100 Ų10094.1 Ų94.151%0.51352%0.523SS..Hα-helixtrans-60.2-44.3175.9-68.5165.3000110.4L455 A456 I457 V462 V463L455-I459 HydrophobicContact CD2-CD1 4.3Å; L455-I459 VanDerWaalsContact O-CG1 3.26Å; L455-I459 WeakPolarHBondContact O-CG1 3.11Å; L455-I459 PolarHBondContact O-N 3.26Å; A456-I459 PolarHBondContact O-N 2.04Å; I457-I459 PolarHBondContact O-N 3.48Å; I459-V462 PolarHBondContact O-N 3.12Å; I459-V463 HydrophobicContact CG2-CG2 4.48Å; I459-V463 WeakPolarHBondContact O-CG2 3.4Å; I459-V463 PolarHBondContact O-N 3.34Å
460L88Confident82.8Confident107 Ų10795 Ų9556%0.5652%0.523SS*.Hα-helixtrans-65.2-40.5-179.9-155.1155.1000111.5A456 I457 I458 V463 L464A456-L460 WeakPolarHBondContact O-CB 3.05Å; A456-L460 PolarHBondContact O-N 2.88Å; I457-L460 PolarHBondContact O-N 2.61Å; I458-L460 VanDerWaalsContact C-N 3.32Å; I458-L460 PolarHBondContact O-N 2.74Å; L460-V463 PolarHBondContact O-N 2.04Å; L460-L464 HydrophobicContact CD2-CD1 3.6Å; L460-L464 HydrophobicContact CD2-CG 4.03Å; L460-L464 WeakPolarHBondContact O-CB 3.22Å; L460-L464 WeakPolarHBondContact O-CG 3.39Å; L460-L464 PolarHBondContact O-N 2.99Å
461L89.8Confident82.1Confident103 Ų10393.9 Ų93.954%0.53952%0.517SS..Hα-helixtrans-65.1-39.6172.9-71.7173.9000112.7I457 I458 L464 C465I457-L461 HydrophobicContact CG2-CD1 3.99Å; I457-L461 HydrophobicContact CG2-CG 4.36Å; I457-L461 WeakPolarHBondContact O-CB 3.39Å; I457-L461 WeakPolarHBondContact O-CG 3.17Å; I457-L461 PolarHBondContact O-N 2.75Å; I458-L461 PolarHBondContact O-N 3.12Å; L461-L464 PolarHBondContact O-N 3.33Å; L461-C465 WeakPolarHBondContact O-CB 3.05Å; L461-C465 PolarHBondContact O-N 2.99Å
462V89.1Confident81.2Confident93 Ų9397 Ų9756%0.56452%0.521SS*.Hα-helixtrans-64.9-41.7174.4169.10000111I458 I459 C465 Y466I458-V462 HydrophobicContact CG2-CG2 4.48Å; I458-V462 VanDerWaalsContact O-CG2 3.32Å; I458-V462 WeakPolarHBondContact O-CG2 3.48Å; I458-V462 PolarHBondContact O-N 2.85Å; I459-V462 PolarHBondContact O-N 3.12Å; V462-C465 PolarHBondContact O-N 3.17Å; V462-Y466 VanDerWaalsContact O-CB 3.31Å; V462-Y466 WeakPolarHBondContact O-CB 3.47Å; V462-Y466 PolarHBondContact O-N 3.35Å
463V87.4Confident79.9Confident78 Ų78100.6 Ų100.647%0.47353%0.531SS..Hα-helixtrans-63.8-44.8174.4170.30000111.1I459 L460 Y466 C467I459-V463 HydrophobicContact CG2-CG2 4.48Å; I459-V463 WeakPolarHBondContact O-CG2 3.4Å; I459-V463 PolarHBondContact O-N 3.34Å; L460-V463 PolarHBondContact O-N 2.04Å; V463-Y466 PolarHBondContact O-N 3.48Å; V463-C467 WeakPolarHBondContact O-CB 3.34Å; V463-C467 PolarHBondContact O-N 3.03Å; V463-C467 PolarHBondContact O-SG 3.23Å; V463-C467 VanDerWaalsContact O-SG 3.35Å
464L86.1Confident78.3Confident98 Ų98103.2 Ų103.251%0.51354%0.541SS..Hα-helixtrans-62.5-43.7175.7-73.7174.2000112L460 L461 C467 F468L460-L464 HydrophobicContact CD2-CD1 3.6Å; L460-L464 HydrophobicContact CD2-CG 4.03Å; L460-L464 WeakPolarHBondContact O-CB 3.22Å; L460-L464 WeakPolarHBondContact O-CG 3.39Å; L460-L464 PolarHBondContact O-N 2.99Å; L461-L464 PolarHBondContact O-N 3.33Å; L464-C467 PolarHBondContact O-N 2.73Å; L464-F468 WeakPolarHBondContact O-CB 3.07Å; L464-F468 PolarHBondContact O-N 3.14Å
465C81.9Confident76.5Confident84 Ų84109.8 Ų109.857%0.56856%0.564SS**Hα-helixtrans-61.7-42.6173.3-95.40000112.1L461 V462 F468 M469L461-C465 WeakPolarHBondContact O-CB 3.05Å; L461-C465 PolarHBondContact O-N 2.99Å; V462-C465 PolarHBondContact O-N 3.17Å; C465-F468 PolarHBondContact O-N 3.2Å; C465-M469 VanDerWaalsContact O-CB 3.3Å; C465-M469 WeakPolarHBondContact O-CB 3.04Å; C465-M469 WeakPolarHBondContact O-CG 3.46Å; C465-M469 PolarHBondContact O-N 3.21Å
466Y81.6Confident74.4Confident150 Ų150110.7 Ų110.759%0.58857%0.574SS**Hα-helixtrans-62.5-45.8176176.9-94.1000111.6V462 V463 F468 M469 K470V462-Y466 VanDerWaalsContact O-CB 3.31Å; V462-Y466 WeakPolarHBondContact O-CB 3.47Å; V462-Y466 PolarHBondContact O-N 3.35Å; V463-Y466 PolarHBondContact O-N 3.48Å; Y466-F468 PolarHBondContact O-N 3.23Å; Y466-M469 PolarHBondContact O-N 2.81Å; Y466-K470 HydrophobicContact CE1-CD 4.13Å; Y466-K470 VanDerWaalsContact O-CB 3.28Å; Y466-K470 WeakPolarHBondContact O-CB 3.08Å; Y466-K470 PolarHBondContact O-N 3.31Å
467C79.8Confident72.4Confident70 Ų70119.3 Ų119.347%0.47360%0.595SS.*Hα-helixtrans-60.8-42.4174.6-74.50000112V463 L464 K470 G471V463-C467 WeakPolarHBondContact O-CB 3.34Å; V463-C467 PolarHBondContact O-N 3.03Å; V463-C467 PolarHBondContact O-SG 3.23Å; V463-C467 VanDerWaalsContact O-SG 3.35Å; L464-C467 PolarHBondContact O-N 2.73Å; C467-K470 PolarHBondContact O-N 3.05Å; C467-G471 PolarHBondContact O-N 2.81Å
468F76.1Confident70.1Confident137 Ų137126.2 Ų126.260%0.60161%0.614SS**Hα-helixtrans-67.4-41.2177.5-168-104.1000112.5L464 C465 Y466 K470 G471 K472L464-F468 WeakPolarHBondContact O-CB 3.07Å; L464-F468 PolarHBondContact O-N 3.14Å; C465-F468 PolarHBondContact O-N 3.2Å; Y466-F468 PolarHBondContact O-N 3.23Å; F468-K470 VanDerWaalsContact C-N 3.34Å; F468-G471 PolarHBondContact O-N 2.75Å; F468-K472 HydrophobicContact CD1-CD 4.48Å; F468-K472 HydrophobicContact CE1-CD 4.08Å; F468-K472 PolarHBondContact O-N 3.04Å
469M74.4Confident67.7Low131 Ų131129 Ų12965%0.64562%0.624SS**Hα-helixtrans-65.9-35.6174.1-73.1-72.8-79.400112.1C465 Y466 K473C465-M469 VanDerWaalsContact O-CB 3.3Å; C465-M469 WeakPolarHBondContact O-CB 3.04Å; C465-M469 WeakPolarHBondContact O-CG 3.46Å; C465-M469 PolarHBondContact O-N 3.21Å; Y466-M469 PolarHBondContact O-N 2.81Å; M469-K473 PolarHBondContact O-N 2.03Å
470K68.9Low65Low120 Ų120133.5 Ų133.552%0.52264%0.635SS.*Hα-helixtrans-69.4-42.5173.7-167.3174.3179.2-178.80111.4Y466 C467 F468 K473Y466-K470 HydrophobicContact CE1-CD 4.13Å; Y466-K470 VanDerWaalsContact O-CB 3.28Å; Y466-K470 WeakPolarHBondContact O-CB 3.08Å; Y466-K470 PolarHBondContact O-N 3.31Å; C467-K470 PolarHBondContact O-N 3.05Å; F468-K470 VanDerWaalsContact C-N 3.34Å; K470-K473 WeakPolarHBondContact O-CA 3.24Å; K470-K473 VanDerWaalsContact O-CB 3.27Å; K470-K473 WeakPolarHBondContact O-CB 3.3Å; K470-K473 PolarHBondContact O-N 3.36Å
471G57.7Low62.5Low35 Ų35134.4 Ų134.436%0.36165%0.645SS.*Hα-helixtrans-61.3-42.6173.900000113.4C467 F468 K473 E474 Q475C467-G471 PolarHBondContact O-N 2.81Å; F468-G471 PolarHBondContact O-N 2.75Å; G471-K473 PolarHBondContact O-N 3.25Å; G471-E474 PolarHBondContact O-N 2.85Å; G471-E474 VanDerWaalsContact O-N 3.17Å; G471-Q475 PolarHBondContact O-N 2.88Å
472K58.4Low60.4Low123 Ų123134.4 Ų134.454%0.53565%0.651SS.*Hα-helixtrans-61.4-26171.7-84.4-172.3171.5-178.60113.4F468 E474 T476F468-K472 HydrophobicContact CD1-CD 4.48Å; F468-K472 HydrophobicContact CE1-CD 4.08Å; F468-K472 PolarHBondContact O-N 3.04Å; K472-E474 VanDerWaalsContact C-N 3.33Å; K472-T476 PolarHBondContact O-OG1 3.08Å
473K51.1Low57.9Low184 Ų184135.9 Ų135.980%0.866%0.66SS**Hα-helixtrans-73.2-22.5177.8-125175.2-175.6178.60113.4M469 K470 G471M469-K473 PolarHBondContact O-N 2.03Å; K470-K473 WeakPolarHBondContact O-CA 3.24Å; K470-K473 VanDerWaalsContact O-CB 3.27Å; K470-K473 WeakPolarHBondContact O-CB 3.3Å; K470-K473 PolarHBondContact O-N 3.36Å; G471-K473 PolarHBondContact O-N 3.25Å
474E50.5Low55.3Low160 Ų160140.1 Ų140.175%0.74868%0.68SS**Hα-helixtrans-94.2-28.8177.1-68.9-174.816200113.4G471 K472 T476G471-E474 PolarHBondContact O-N 2.85Å; G471-E474 VanDerWaalsContact O-N 3.17Å; K472-E474 VanDerWaalsContact C-N 3.33Å; E474-T476 VanDerWaalsContact C-N 3.33Å; E474-T476 PolarHBondContact O-N 3.38Å
475Q47.1Very low52.8Low169 Ų169138.7 Ų138.779%0.7969%0.689SS**Hα-helixtrans-75.7-11.3179.9-92.5-178.9-26.100115.5G471 R477G471-Q475 PolarHBondContact O-N 2.88Å; Q475-R477 PolarHBondContact O-N 2.53Å; Q475-R477 VanDerWaalsContact O-N 3.14Å
476T43.9Very low50.5Low121 Ų121140.1 Ų140.174%0.74270%0.7SS**SBendtrans-86.527.6-175-39.70000113.8K472 E474K472-T476 PolarHBondContact O-OG1 3.08Å; E474-T476 VanDerWaalsContact C-N 3.33Å; E474-T476 PolarHBondContact O-N 3.38Å
477R42.8Very low48.3Very low235 Ų235141.4 Ų141.489%0.88771%0.712SS**  trans-138.962.2178.3-104.8-171.1176.4-174-0.1113.8Q475Q475-R477 PolarHBondContact O-N 2.53Å; Q475-R477 VanDerWaalsContact O-N 3.14Å
478R39.6Very low46.1Very low248 Ų248145.1 Ų145.194%0.93673%0.732SS**  trans-163.8159.1150.2-108.2162.1-160.8-157.25.3113
479Q38.5Very low44.1Very low162 Ų162148.4 Ų148.476%0.75774%0.741SS**  trans-154.7162.8-157.3-115-166.643.600109.2
480R32.9Very low42.3Very low195 Ų195148.3 Ų148.374%0.73675%0.748SS**  cis-162141.96.1-155.1-171.5-169.9157.4-2.5108.3
481V35.8Very low40.8Very low126 Ų126151.5 Ų151.576%0.76476%0.757SS**  trans65.1154.6143.9144.50000118.3
482P44.6Very low39.9Very low103 Ų103155.9 Ų155.967%0.66977%0.768SS**  cis-141.3164.9-28.740.7-22.1000117.7
483V37.4Very low38.9Very low125 Ų125156.8 Ų156.876%0.75878%0.779SS**  trans42.5121.1132.9-177.70000122.3
484N31.8Very low38.3Very low166 Ų166153.8 Ų153.889%0.88878%0.776SS**  -176.5153.1106.6-121.5-19.1000114.2
485G33.2Very low37.9Very low69 Ų69154.5 Ų154.571%0.71178%0.78SS**  trans130.4101.6158.200000119.8
486S33.6Very low37.4Very low114 Ų114158.3 Ų158.380%0.79779%0.787SS**  trans-33.5132162.8430000118.1
487Q35.5Very low37.3Very low177 Ų177160.3 Ų160.383%0.82779%0.792SS**  66.8117.883.8-84.7-158.3-12.400118.3
488V35.3Very low36.9Very low147 Ų147156 Ų15689%0.89179%0.791SS**  trans-151.2151.2142.5179.60000109.7
489Y33.3Very low36.8Very low206 Ų206154.5 Ų154.581%0.80879%0.787SS**  trans-70.1175.2178.5-73.2-117.9000113.2
490T36.4Very low36.8Very low129 Ų129154.3 Ų154.379%0.79179%0.792SS**  cis-162.5-177.838.933.60000110.5
491R37Very low37.2Very low188 Ų188150.4 Ų150.471%0.70979%0.789SS**  cis178.4129.5-34.2175.6-172.7161.1169.5-0.1109.7
492E39Very low37.4Very low127 Ų127150.4 Ų150.459%0.59379%0.79SS**  trans63.7134159.8-76.8158.5-143.600119.7
493D37.1Very low37.3Very low141 Ų141151.7 Ų151.775%0.75480%0.796SS**  72.9147.968.2-69.7-33.4000113.4
494T39.2Very low37.1Very low121 Ų121154.9 Ų154.974%0.74280%0.8SS**  cis-155.5177.810.6-3.90000112.6
495E41.8Very low38.2Very low176 Ų176152 Ų15282%0.82279%0.79SS**  trans-45160.7172.5-49.8169.4144.100118.4
496R36.8Very low38.6Very low249 Ų249160.1 Ų160.194%0.9482%0.815SS**  -168.9140.5120.8-107.5171.9-171.4-155.70.9115.8
497L41.4Very low38.8Very low162 Ų162162.5 Ų162.585%0.84882%0.816SS**  trans-82.5166.5161.9-69.5153.7000110.8
498V34.2Very low39Very low145 Ų145161.7 Ų161.788%0.87982%0.815SS**  179142.3129.9145.50000111.8
499Y38.1Very low39.2Very low217 Ų217162.5 Ų162.585%0.85181%0.811SS**  trans-71.5165.5173.9-81.3-105.7000113
500N37.6Very low39.5Very low158 Ų158159.9 Ų159.985%0.84581%0.811SS**  trans-150144153.4-144.3-2000113.8
501T42.2Very low39.7Very low112 Ų112161.9 Ų161.969%0.68781%0.812SS**  trans-143.5133.9178.342.80000111
502T40.4Very low39.9Very low127 Ų127160.1 Ų160.178%0.77982%0.819SS**  trans64.6147.9167.623.20000116.2
503T41.3Very low40Very low130 Ų130162.5 Ų162.580%0.79884%0.835SS**  cis-157.3167.727.9-200000112.8
504K34.7Very low40.2Very low192 Ų192164.2 Ų164.284%0.83584%0.841SS**  trans-43.6178.3162.5-107.4-179.5177.1-178.70116
505P54.9Low40.3Very low105 Ų105167.8 Ų167.868%0.68285%0.85SS**  cis-136-179.9-9.239.8-22.3000115.1
506I40Very low40.2Very low240 Ų240167 Ų167100%1.23185%0.852SS**  -1600116.5-95.2161.6000107.5

Retrieved 506 of 506 residues in 1194 ms (Link to these results)