A0A060WWS3_ONCMY Loading...

UDP-sugar transporter protein SLC35A4

AlphaFold DB , UniProt , Accession A0A060WWS3, Species ONCMY (Oncorhynchus mykiss, Rainbow trout), Gene slc35a4, Length 325 aa.

Structure Viewer
Loading PAE data...
(Predicted Aligned Error values between residue pairs)
Error loading PAE data: please refresh the page.

 

Download Structure   PDB   PAE   Table  
Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M35.8Very low42.2Very low234 Ų234142.6 Ų142.6100%1.15376%0.762SS**  093.70-164.6171.2169.600107.4V3M1-V3 PolarHBondContact O-N 3.48Å
2I35.2Very low43.8Very low160 Ų160140.3 Ų140.382%0.82176%0.761SS**  trans-84.2107-174.5-64.8169000107.3I4I2-I4 HydrophobicContact CG2-CG1 4.3Å; I2-I4 PolarHBondContact O-N 3.36Å
3V34.6Very low45.7Very low123 Ų123133.9 Ų133.975%0.74573%0.733SS**  trans-77.898.9173.4178.70000107.2M1 H5M1-V3 PolarHBondContact O-N 3.48Å; V3-H5 PolarHBondContact O-N 3.4Å; V3-H5 VanDerWaalsContact O-N 3.16Å
4I38.8Very low47.5Very low147 Ų147137.4 Ų137.475%0.75473%0.73SS**  trans-68.1109.4170.5-61.2172.6000106.8I2 N6I2-I4 HydrophobicContact CG2-CG1 4.3Å; I2-I4 PolarHBondContact O-N 3.36Å; I4-N6 PolarHBondContact O-N 3.37Å
5H34.2Very low49.1Very low175 Ų175136.1 Ų136.181%0.8172%0.718SS**  trans-62.4105.6171.6-120.5-67.8000108.1V3 V7V3-H5 PolarHBondContact O-N 3.4Å; V3-H5 VanDerWaalsContact O-N 3.16Å; H5-V7 PolarHBondContact O-N 2.9Å
6N40.8Very low50.8Low148 Ų148140.8 Ų140.879%0.79172%0.723SS**  trans-60.8108.3179.3-146.1-2.8000108.5I4 R8I4-N6 PolarHBondContact O-N 3.37Å; N6-R8 PolarHBondContact O-N 3.23Å
7V46.5Very low52.5Low129 Ų129141.9 Ų141.978%0.78272%0.716SS**  trans-61105.1171.8174.50000106.3H5 S9H5-V7 PolarHBondContact O-N 2.9Å; V7-S9 PolarHBondContact O-N 2.88Å
8R41.7Very low54.1Low242 Ų242140.1 Ų140.191%0.91370%0.699SS**  trans-53.4106170.4-90.1179.6172.2175.6-2.1108.2N6 G10N6-R8 PolarHBondContact O-N 3.23Å; R8-G10 PolarHBondContact O-N 3.11Å; R8-G10 VanDerWaalsContact O-N 3.16Å
9S48.6Very low55.6Low111 Ų111141.1 Ų141.178%0.77669%0.694SS**PPolyproline II helixtrans-52.1117.1163.647.40000108.3V7 S11V7-S9 PolarHBondContact O-N 2.88Å; S9-S11 PolarHBondContact O-N 3.42Å
10G49.3Very low57.2Low43 Ų43142.6 Ų142.644%0.44369%0.691SS.*PPolyproline II helixtrans-60.2123.9173.900000108.8R8R8-G10 PolarHBondContact O-N 3.11Å; R8-G10 VanDerWaalsContact O-N 3.16Å
11S58.3Low58.6Low57 Ų57142.4 Ų142.440%0.39969%0.687SS.*PPolyproline II helixtrans-54.7140.6-177.467.70000111.6S9 S13 R14S9-S11 PolarHBondContact O-N 3.42Å; S11-S13 PolarHBondContact O-N 3.01Å; S11-S13 PolarHBondContact OG-OG 2.86Å; S11-R14 WeakPolarHBondContact O-CB 3.49Å; S11-R14 PolarHBondContact O-N 3.26Å
12P61.9Low61Low115 Ų115138.4 Ų138.475%0.74766%0.659SS**Hα-helixtrans-56.4-25.1-177.116.6-29000113.4R14 R16P12-R14 VanDerWaalsContact C-N 3.31Å; P12-R14 PolarHBondContact O-N 3.23Å; P12-R16 WeakPolarHBondContact O-CB 3.41Å; P12-R16 PolarHBondContact O-N 3.34Å; P12-R16 VanDerWaalsContact O-N 3.11Å
13S68.4Low63.7Low57 Ų57134.7 Ų134.740%0.39964%0.644SS.*Hα-helixtrans-69.2-23.4174.773.90000114.2S11 R17S11-S13 PolarHBondContact O-N 3.01Å; S11-S13 PolarHBondContact OG-OG 2.86Å; S13-R17 WeakPolarHBondContact O-CB 3.47Å; S13-R17 WeakPolarHBondContact O-CG 3.48Å; S13-R17 PolarHBondContact O-N 3.39Å; S13-R17 PolarHBondContact O-NE 3.45Å; S13-R17 VanDerWaalsContact O-NE 3.12Å; S13-R17 PolarHBondContact OG-NH2 2.95Å
14R71Confident66.3Low183 Ų183133.4 Ų133.469%0.69163%0.63SS**Hα-helixtrans-80.5-41.9177.7-143.3174.9103.4-177.44.6111S11 P12 R17 W18S11-R14 WeakPolarHBondContact O-CB 3.49Å; S11-R14 PolarHBondContact O-N 3.26Å; P12-R14 VanDerWaalsContact C-N 3.31Å; P12-R14 PolarHBondContact O-N 3.23Å; R14-R17 PolarHBondContact O-N 2.89Å; R14-W18 WeakPolarHBondContact O-CB 3.45Å; R14-W18 PolarHBondContact O-N 3.29Å
15H71.4Confident68.9Low118 Ų118130.4 Ų130.455%0.54661%0.609SS.*Hα-helixtrans-62.5-44.5172.7-98.4-62000112.1R17 W18 W19H15-R17 PolarHBondContact O-N 3.49Å; H15-W18 PolarHBondContact O-N 3.29Å; H15-W19 WeakPolarHBondContact O-CB 3.31Å; H15-W19 PolarHBondContact O-N 3.42Å
16R76.3Confident71.6Confident210 Ų210124.1 Ų124.179%0.79259%0.592SS**Hα-helixtrans-64.1-39.9179.1-161.5175.5-176.4-135.21.6112.8P12 R20P12-R16 WeakPolarHBondContact O-CB 3.41Å; P12-R16 PolarHBondContact O-N 3.34Å; P12-R16 VanDerWaalsContact O-N 3.11Å; R16-R20 WeakPolarHBondContact O-CB 3.44Å; R16-R20 PolarHBondContact O-N 3.12Å
17R79Confident74.2Confident160 Ų160121.7 Ų121.760%0.60458%0.582SS**Hα-helixtrans-66.9-40.1175.2-83.5-176.5-77.2-160.1-2.3112.8S13 R14 H15 K21S13-R17 WeakPolarHBondContact O-CB 3.47Å; S13-R17 WeakPolarHBondContact O-CG 3.48Å; S13-R17 PolarHBondContact O-N 3.39Å; S13-R17 PolarHBondContact O-NE 3.45Å; S13-R17 VanDerWaalsContact O-NE 3.12Å; S13-R17 PolarHBondContact OG-NH2 2.95Å; R14-R17 PolarHBondContact O-N 2.89Å; H15-R17 PolarHBondContact O-N 3.49Å; R17-K21 WeakPolarHBondContact O-CG 3.24Å; R17-K21 PolarHBondContact O-N 3.35Å
18W81.5Confident76.5Confident109 Ų109117.1 Ų117.141%0.41355%0.553SS.*Hα-helixtrans-64.8-45.6176.5175.392000111.8R14 H15 K21 R22R14-W18 WeakPolarHBondContact O-CB 3.45Å; R14-W18 PolarHBondContact O-N 3.29Å; H15-W18 PolarHBondContact O-N 3.29Å; W18-K21 PolarHBondContact O-N 3.39Å; W18-R22 VanDerWaalsContact CZ2-NH2 3.27Å; W18-R22 PolarHBondContact O-N 2.99Å
19W83.8Confident79Confident159 Ų159107.9 Ų107.960%0.60252%0.521SS*.Hα-helixtrans-60.3-47.1175.1-99.5104.2000111.6H15 K21 R22 V23H15-W19 WeakPolarHBondContact O-CB 3.31Å; H15-W19 PolarHBondContact O-N 3.42Å; W19-K21 VanDerWaalsContact C-N 3.32Å; W19-K21 PolarHBondContact O-N 3.5Å; W19-R22 PolarHBondContact O-N 2.83Å; W19-R22 VanDerWaalsContact O-N 3.14Å; W19-V23 HydrophobicContact CE3-CG2 4.26Å; W19-V23 WeakPolarHBondContact O-CG2 3.43Å; W19-V23 PolarHBondContact O-N 2.92Å
20R86.8Confident81.2Confident172 Ų172104.5 Ų104.565%0.64951%0.505SS*.Hα-helixtrans-57.9-43.5177.2-172.4177.1-179.6-125.72.7112.1R16 V23 Q24R16-R20 WeakPolarHBondContact O-CB 3.44Å; R16-R20 PolarHBondContact O-N 3.12Å; R20-V23 PolarHBondContact O-N 3.13Å; R20-Q24 WeakPolarHBondContact O-CB 3.32Å; R20-Q24 VanDerWaalsContact O-CG 3.24Å; R20-Q24 WeakPolarHBondContact O-CG 3.43Å; R20-Q24 PolarHBondContact O-N 2.96Å
21K86.4Confident83.5Confident139 Ų139106.2 Ų106.260%0.60450%0.503SS*.Hα-helixtrans-62.5-43.4175.9-76.5-175.3177.1-1710112R17 W18 W19 Q24 W25R17-K21 WeakPolarHBondContact O-CG 3.24Å; R17-K21 PolarHBondContact O-N 3.35Å; W18-K21 PolarHBondContact O-N 3.39Å; W19-K21 VanDerWaalsContact C-N 3.32Å; W19-K21 PolarHBondContact O-N 3.5Å; K21-Q24 PolarHBondContact O-N 3.22Å; K21-W25 VanDerWaalsContact O-CD1 3.25Å; K21-W25 PolarHBondContact O-N 2.82Å
22R87.4Confident85.3Confident150 Ų150103.5 Ų103.557%0.56648%0.484SS*.Hα-helixtrans-61.2-44.7176.3-81.2-169.8166.8-165.8-0.8112.2W18 W19 W25 G26W18-R22 VanDerWaalsContact CZ2-NH2 3.27Å; W18-R22 PolarHBondContact O-N 2.99Å; W19-R22 PolarHBondContact O-N 2.83Å; W19-R22 VanDerWaalsContact O-N 3.14Å; R22-W25 PolarHBondContact O-N 3.1Å; R22-G26 PolarHBondContact O-N 3.36Å
23V90.1Very high86.9Confident82 Ų8299.2 Ų99.250%0.49746%0.456SS..Hα-helixtrans-62.1-45176.51740000110.7W19 R20 W25 G26 V27W19-V23 HydrophobicContact CE3-CG2 4.26Å; W19-V23 WeakPolarHBondContact O-CG2 3.43Å; W19-V23 PolarHBondContact O-N 2.92Å; R20-V23 PolarHBondContact O-N 3.13Å; V23-W25 VanDerWaalsContact C-N 3.35Å; V23-W25 PolarHBondContact O-N 3.31Å; V23-G26 PolarHBondContact O-N 3.33Å; V23-V27 HydrophobicContact CG1-CG2 4.34Å; V23-V27 WeakPolarHBondContact O-CG2 3.39Å; V23-V27 PolarHBondContact O-N 3.27Å
24Q90.9Very high88.2Confident95 Ų95101 Ų10144%0.44446%0.46SS..Hα-helixtrans-59-44.2176.6-75.2173.7-32.400112.5R20 K21 L28R20-Q24 WeakPolarHBondContact O-CB 3.32Å; R20-Q24 VanDerWaalsContact O-CG 3.24Å; R20-Q24 WeakPolarHBondContact O-CG 3.43Å; R20-Q24 PolarHBondContact O-N 2.96Å; K21-Q24 PolarHBondContact O-N 3.22Å; Q24-L28 VanDerWaalsContact O-CB 3.31Å; Q24-L28 WeakPolarHBondContact O-CB 3.38Å; Q24-L28 PolarHBondContact O-N 2.99Å
25W92.6Very high89.4Confident84 Ų8493.5 Ų93.532%0.31843%0.434SS..Hα-helixtrans-65.3-42.2174.9-86.2103.2000112.3K21 R22 V23 L28 L29 V273 H276K21-W25 VanDerWaalsContact O-CD1 3.25Å; K21-W25 PolarHBondContact O-N 2.82Å; R22-W25 PolarHBondContact O-N 3.1Å; V23-W25 VanDerWaalsContact C-N 3.35Å; V23-W25 PolarHBondContact O-N 3.31Å; W25-L28 HydrophobicContact CE3-CD2 4.36Å; W25-L28 HydrophobicContact CZ3-CD2 4.33Å; W25-L28 PolarHBondContact O-N 2.98Å; W25-L29 HydrophobicContact CE3-CG 4.46Å; W25-L29 WeakPolarHBondContact O-CB 3.38Å; W25-L29 VanDerWaalsContact O-CG 3.24Å; W25-L29 WeakPolarHBondContact O-CG 3.45Å; W25-L29 PolarHBondContact O-N 2.98Å; W25-V273 HydrophobicContact CZ3-CG2 4.35Å; W25-H276 HydrophobicContact CH2-CB 3.77Å; W25-H276 HydrophobicContact CZ2-CB 3.64Å
26G91.7Very high90.5Very high44 Ų4491.6 Ų91.645%0.45442%0.422SS..Hα-helixtrans-59.6-46.1175.800000112.2R22 V23 L29 G30R22-G26 PolarHBondContact O-N 3.36Å; V23-G26 PolarHBondContact O-N 3.33Å; G26-L29 PolarHBondContact O-N 3.14Å; G26-G30 PolarHBondContact O-N 3.14Å
27V93.9Very high91.2Very high96 Ų9681.7 Ų81.758%0.58239%0.385SS*.Hα-helixtrans-62.9-45.2175.9172.20000111.1V23 G30 L31V23-V27 HydrophobicContact CG1-CG2 4.34Å; V23-V27 WeakPolarHBondContact O-CG2 3.39Å; V23-V27 PolarHBondContact O-N 3.27Å; V27-G30 PolarHBondContact O-N 3.18Å; V27-L31 WeakPolarHBondContact O-CB 3.41Å; V27-L31 PolarHBondContact O-N 3.39Å
28L95Very high91.9Very high34 Ų3475.2 Ų75.218%0.17837%0.365CS..Hα-helixtrans-59.9-50178.4-178.1150.4000111.4Q24 W25 L31 M32 L269 V272 V273Q24-L28 VanDerWaalsContact O-CB 3.31Å; Q24-L28 WeakPolarHBondContact O-CB 3.38Å; Q24-L28 PolarHBondContact O-N 2.99Å; W25-L28 HydrophobicContact CE3-CD2 4.36Å; W25-L28 HydrophobicContact CZ3-CD2 4.33Å; W25-L28 PolarHBondContact O-N 2.98Å; L28-L31 PolarHBondContact O-N 2.97Å; L28-M32 HydrophobicContact CD2-CG 4.38Å; L28-M32 HydrophobicContact CD2-SD 3.55Å; L28-M32 VanDerWaalsContact CD2-SD 3.55Å; L28-M32 VanDerWaalsContact O-CG 3.31Å; L28-M32 WeakPolarHBondContact O-CG 3.49Å; L28-M32 PolarHBondContact O-N 3.47Å; L28-L269 HydrophobicContact CD1-CD2 4.27Å; L28-L269 HydrophobicContact CG-CD2 4.21Å; L28-V272 HydrophobicContact CD1-CG1 3.91Å; L28-V273 HydrophobicContact CD2-CG2 3.81Å
29L95.1Very high92.4Very high47 Ų4772.9 Ų72.925%0.24636%0.358CS..Hα-helixtrans-66.2-41.2-179.7-64.7173.1000111.3W25 G26 L31 M32 V33 V273 T281 V285W25-L29 HydrophobicContact CE3-CG 4.46Å; W25-L29 WeakPolarHBondContact O-CB 3.38Å; W25-L29 VanDerWaalsContact O-CG 3.24Å; W25-L29 WeakPolarHBondContact O-CG 3.45Å; W25-L29 PolarHBondContact O-N 2.98Å; G26-L29 PolarHBondContact O-N 3.14Å; L29-L31 PolarHBondContact O-N 3.32Å; L29-M32 PolarHBondContact O-N 3.16Å; L29-V33 WeakPolarHBondContact O-CB 3.28Å; L29-V33 VanDerWaalsContact O-CG2 3.28Å; L29-V33 WeakPolarHBondContact O-CG2 3.24Å; L29-V33 PolarHBondContact O-N 3.16Å; L29-V273 HydrophobicContact CD2-CG2 4.12Å; L29-T281 HydrophobicContact CD1-CG2 4.43Å; L29-T281 HydrophobicContact CD2-CG2 3.9Å; L29-V285 HydrophobicContact CD2-CG2 3.56Å
30G95.3Very high92.6Very high41 Ų4167.4 Ų67.442%0.42335%0.347SS..Hα-helixtrans-60.5-43.3175.200000112.6G26 V27 M32 V33 L34G26-G30 PolarHBondContact O-N 3.14Å; V27-G30 PolarHBondContact O-N 3.18Å; G30-M32 PolarHBondContact O-N 3.36Å; G30-V33 PolarHBondContact O-N 2.92Å; G30-L34 WeakPolarHBondContact O-CB 3.46Å; G30-L34 PolarHBondContact O-N 2.94Å
31L96Very high92.7Very high79 Ų7959.2 Ų59.241%0.41432%0.316SS..Hα-helixtrans-62.7-42.4175.1-178.264.7000111.6V27 L28 L29 L34 I35 L269V27-L31 WeakPolarHBondContact O-CB 3.41Å; V27-L31 PolarHBondContact O-N 3.39Å; L28-L31 PolarHBondContact O-N 2.97Å; L29-L31 PolarHBondContact O-N 3.32Å; L31-L34 PolarHBondContact O-N 2.91Å; L31-I35 HydrophobicContact CD1-CD1 3.87Å; L31-I35 HydrophobicContact CD1-CG1 4.15Å; L31-I35 HydrophobicContact CD2-CD1 4.33Å; L31-I35 HydrophobicContact CG-CD1 3.71Å; L31-I35 HydrophobicContact CG-CG1 4.36Å; L31-I35 WeakPolarHBondContact O-CB 3.44Å; L31-I35 VanDerWaalsContact O-CG1 3.26Å; L31-I35 WeakPolarHBondContact O-CG1 3.48Å; L31-I35 PolarHBondContact O-N 3.04Å; L31-L269 HydrophobicContact CD2-CD1 4.09Å; L31-L269 HydrophobicContact CG-CD1 4.35Å
32M95.9Very high92.9Very high0 Ų054.2 Ų54.20%030%0.296CS..Hα-helixtrans-63.5-43.7176.3-69.4177.777.400112.4L28 L29 G30 L34 I35 Y36 L269 M270 V273 V285L28-M32 HydrophobicContact CD2-CG 4.38Å; L28-M32 HydrophobicContact CD2-SD 3.55Å; L28-M32 VanDerWaalsContact CD2-SD 3.55Å; L28-M32 VanDerWaalsContact O-CG 3.31Å; L28-M32 WeakPolarHBondContact O-CG 3.49Å; L28-M32 PolarHBondContact O-N 3.47Å; L29-M32 PolarHBondContact O-N 3.16Å; G30-M32 PolarHBondContact O-N 3.36Å; M32-L34 VanDerWaalsContact C-N 3.29Å; M32-L34 PolarHBondContact O-N 3.39Å; M32-I35 PolarHBondContact O-N 3.3Å; M32-Y36 WeakPolarHBondContact O-CB 3.44Å; M32-Y36 PolarHBondContact O-N 3.05Å; M32-L269 HydrophobicContact CE-CB 3.92Å; M32-L269 HydrophobicContact CG-CB 3.58Å; M32-L269 HydrophobicContact CG-CD1 3.68Å; M32-L269 HydrophobicContact CG-CG 4.21Å; M32-L269 HydrophobicContact SD-CB 3.73Å; M32-M270 HydrophobicContact CE-CB 4.21Å; M32-M270 HydrophobicContact CE-CE 3.63Å; M32-M270 HydrophobicContact CE-CG 3.56Å; M32-M270 HydrophobicContact CE-SD 3.33Å; M32-M270 WeakPolarHBondContact CE-SD 3.41Å; M32-V273 HydrophobicContact CE-CG2 3.79Å; M32-V273 HydrophobicContact SD-CG2 3.37Å; M32-V273 WeakPolarHBondContact SD-CG2 3.48Å; M32-V285 HydrophobicContact CB-CG1 3.65Å; M32-V285 HydrophobicContact CE-CG1 4.32Å
33V96.8Very high93Very high25 Ų2549 Ų4915%0.15228%0.278CS..Hα-helixtrans-59.6-42.4176.21670000110.4L29 G30 G37 V285 C288 S289 V292L29-V33 WeakPolarHBondContact O-CB 3.28Å; L29-V33 VanDerWaalsContact O-CG2 3.28Å; L29-V33 WeakPolarHBondContact O-CG2 3.24Å; L29-V33 PolarHBondContact O-N 3.16Å; G30-V33 PolarHBondContact O-N 2.92Å; V33-G37 PolarHBondContact O-N 2.93Å; V33-V285 HydrophobicContact CG2-CB 4.41Å; V33-V285 HydrophobicContact CG2-CG1 4.03Å; V33-C288 HydrophobicContact CG1-CB 4.01Å; V33-C288 HydrophobicContact CG2-CB 3.73Å; V33-S289 WeakPolarHBondContact O-CB 3.36Å; V33-V292 HydrophobicContact CG1-CG2 3.68Å
34L95.9Very high92.8Very high93 Ų9346.7 Ų46.749%0.48727%0.265SS..Hα-helixtrans-63.8-54.3176.7-17764.3000112G30 L31 M32 Y36 G37 S38 V292G30-L34 WeakPolarHBondContact O-CB 3.46Å; G30-L34 PolarHBondContact O-N 2.94Å; L31-L34 PolarHBondContact O-N 2.91Å; M32-L34 VanDerWaalsContact C-N 3.29Å; M32-L34 PolarHBondContact O-N 3.39Å; L34-Y36 PolarHBondContact O-N 2.72Å; L34-G37 PolarHBondContact O-N 3.36Å; L34-S38 VanDerWaalsContact O-CB 3.24Å; L34-S38 WeakPolarHBondContact O-CB 3.31Å; L34-S38 PolarHBondContact O-N 3.48Å; L34-S38 PolarHBondContact O-OG 3.4Å; L34-V292 HydrophobicContact CD1-CG1 4Å
35I95.3Very high92.6Very high26 Ų2646.3 Ų46.313%0.13327%0.265CS..Hα-helixtrans-61.6-48.3-177.4-66.3169.7000110.4L31 M32 G37 S38 H39 G262 A265 N266 L269L31-I35 HydrophobicContact CD1-CD1 3.87Å; L31-I35 HydrophobicContact CD1-CG1 4.15Å; L31-I35 HydrophobicContact CD2-CD1 4.33Å; L31-I35 HydrophobicContact CG-CD1 3.71Å; L31-I35 HydrophobicContact CG-CG1 4.36Å; L31-I35 WeakPolarHBondContact O-CB 3.44Å; L31-I35 VanDerWaalsContact O-CG1 3.26Å; L31-I35 WeakPolarHBondContact O-CG1 3.48Å; L31-I35 PolarHBondContact O-N 3.04Å; M32-I35 PolarHBondContact O-N 3.3Å; I35-G37 PolarHBondContact O-N 2.86Å; I35-S38 PolarHBondContact O-N 2.92Å; I35-S38 PolarHBondContact O-OG 3.1Å; I35-H39 PolarHBondContact O-N 2.93Å; I35-G262 WeakPolarHBondContact CG2-O 3.47Å; I35-A265 HydrophobicContact CD1-CB 4.2Å; I35-N266 HydrophobicContact CG2-CB 3.88Å; I35-L269 HydrophobicContact CD1-CD1 4.19Å
36Y93.9Very high92.3Very high78 Ų7842.6 Ų42.631%0.30625%0.252SS..Hα-helixtrans-64.2-43-179.4-161.3-76.4000111.4M32 L34 S38 H39 N266 M270 I286 S289M32-Y36 WeakPolarHBondContact O-CB 3.44Å; M32-Y36 PolarHBondContact O-N 3.05Å; L34-Y36 PolarHBondContact O-N 2.72Å; Y36-S38 VanDerWaalsContact C-N 3.33Å; Y36-S38 PolarHBondContact O-N 3.27Å; Y36-H39 VanDerWaalsContact O-CB 3.32Å; Y36-H39 WeakPolarHBondContact O-CB 3.33Å; Y36-H39 PolarHBondContact O-N 3.27Å; Y36-N266 VanDerWaalsContact CD2-ND2 3.26Å; Y36-N266 WeakPolarHBondContact CD2-ND2 3.26Å; Y36-M270 HydrophobicContact CD2-CE 4.19Å; Y36-M270 HydrophobicContact CE2-CE 4.48Å; Y36-I286 HydrophobicContact CE1-CG1 4.42Å; Y36-I286 HydrophobicContact CE1-CG2 4.04Å; Y36-I286 HydrophobicContact CE2-CG1 4.21Å; Y36-S289 WeakPolarHBondContact CD1-OG 3.47Å
37G92.4Very high92Very high2 Ų245 Ų452%0.02125%0.25CC..Hα-helixtrans-69.5-31.5-179.200000112.9V33 L34 I35 H39 P41 S289 N293V33-G37 PolarHBondContact O-N 2.93Å; L34-G37 PolarHBondContact O-N 3.36Å; I35-G37 PolarHBondContact O-N 2.86Å; G37-H39 VanDerWaalsContact C-N 3.26Å; G37-H39 PolarHBondContact O-N 3.16Å; G37-P41 WeakPolarHBondContact O-CD 3.33Å; G37-S289 VanDerWaalsContact CA-O 3.23Å; G37-S289 WeakPolarHBondContact CA-O 3.38Å; G37-N293 VanDerWaalsContact O-CA 3.24Å; G37-N293 WeakPolarHBondContact O-CA 3.11Å; G37-N293 WeakPolarHBondContact O-CB 3.32Å
38S93.6Very high91.2Very high25 Ų2545.8 Ų45.818%0.17526%0.255CS..Hα-helixtrans-71.9-16.517774.80000113.9L34 I35 Y36 P41 L42L34-S38 VanDerWaalsContact O-CB 3.24Å; L34-S38 WeakPolarHBondContact O-CB 3.31Å; L34-S38 PolarHBondContact O-N 3.48Å; L34-S38 PolarHBondContact O-OG 3.4Å; I35-S38 PolarHBondContact O-N 2.92Å; I35-S38 PolarHBondContact O-OG 3.1Å; Y36-S38 VanDerWaalsContact C-N 3.33Å; Y36-S38 PolarHBondContact O-N 3.27Å; S38-P41 VanDerWaalsContact O-CD 3.3Å; S38-P41 WeakPolarHBondContact O-CD 3.37Å; S38-L42 WeakPolarHBondContact O-CB 3.24Å; S38-L42 WeakPolarHBondContact O-CD1 3.34Å; S38-L42 PolarHBondContact O-N 3.42Å; S38-L42 VanDerWaalsContact O-N 3.1Å
39H91.8Very high90.1Very high60 Ų6048 Ų4828%0.27829%0.287SS..Hα-helixtrans-60.8-51.7-173.4177.6-112.1000114I35 Y36 G37 L42 I43 Q263I35-H39 PolarHBondContact O-N 2.93Å; Y36-H39 VanDerWaalsContact O-CB 3.32Å; Y36-H39 WeakPolarHBondContact O-CB 3.33Å; Y36-H39 PolarHBondContact O-N 3.27Å; G37-H39 VanDerWaalsContact C-N 3.26Å; G37-H39 PolarHBondContact O-N 3.16Å; H39-L42 PolarHBondContact O-N 2.89Å; H39-I43 WeakPolarHBondContact CE1-CD1 3.35Å; H39-I43 VanDerWaalsContact NE2-CD1 3.34Å; H39-I43 WeakPolarHBondContact NE2-CD1 3.41Å; H39-I43 WeakPolarHBondContact O-CG1 3.36Å; H39-I43 PolarHBondContact O-N 3.2Å; H39-Q263 VanDerWaalsContact CD2-CD 3.4Å; H39-Q263 PolarHBondContact CD2-NE2 2.88Å; H39-Q263 VanDerWaalsContact CG-NE2 3.27Å
40A88.8Confident89Confident44 Ų4448.8 Ų48.836%0.36431%0.306SS..Hα-helixtrans-68-40.7-175.600000113.5I43 T44A40-I43 PolarHBondContact O-N 2.86Å; A40-T44 PolarHBondContact O-N 3.42Å; A40-T44 PolarHBondContact O-OG1 3.34Å
41P88.9Confident88Confident0 Ų056.7 Ų56.70%032%0.323CS..Hα-helixtrans-65.8-40.5174.5-22.936.3000111.6G37 S38 I43 T44 L45 N293 L296G37-P41 WeakPolarHBondContact O-CD 3.33Å; S38-P41 VanDerWaalsContact O-CD 3.3Å; S38-P41 WeakPolarHBondContact O-CD 3.37Å; P41-I43 PolarHBondContact O-N 3.25Å; P41-T44 WeakPolarHBondContact O-CB 3.41Å; P41-T44 PolarHBondContact O-N 2.97Å; P41-T44 VanDerWaalsContact O-N 3.1Å; P41-L45 WeakPolarHBondContact O-CG 3.43Å; P41-L45 PolarHBondContact O-N 2.96Å; P41-N293 WeakPolarHBondContact CD-OD1 3.36Å; P41-N293 WeakPolarHBondContact CG-OD1 3.44Å; P41-L296 HydrophobicContact CB-CB 4.29Å; P41-L296 HydrophobicContact CG-CB 4.02Å
42L90.5Very high87.3Confident33 Ų3355.5 Ų55.517%0.17332%0.319CS..Hα-helixtrans-61.5-43.8175.9-92.576.1000111.8S38 H39 T44 L45 T46 V255 A258 I259S38-L42 WeakPolarHBondContact O-CB 3.24Å; S38-L42 WeakPolarHBondContact O-CD1 3.34Å; S38-L42 PolarHBondContact O-N 3.42Å; S38-L42 VanDerWaalsContact O-N 3.1Å; H39-L42 PolarHBondContact O-N 2.89Å; L42-T44 VanDerWaalsContact C-N 3.27Å; L42-T44 PolarHBondContact O-N 2.87Å; L42-L45 PolarHBondContact O-N 3.34Å; L42-T46 WeakPolarHBondContact O-CG2 3.38Å; L42-T46 PolarHBondContact O-N 2.93Å; L42-V255 HydrophobicContact CB-CG1 4.26Å; L42-V255 HydrophobicContact CD2-CG1 4.33Å; L42-V255 HydrophobicContact CG-CG1 4.2Å; L42-A258 HydrophobicContact CD2-CB 4.35Å; L42-I259 HydrophobicContact CB-CD1 4.07Å; L42-I259 HydrophobicContact CB-CG1 3.79Å; L42-I259 HydrophobicContact CD2-CG1 4.1Å
43I87.9Confident86.6Confident40 Ų4058 Ų5821%0.20534%0.335CS..Hα-helixtrans-59.3-42.4173.2-74177.4000110.5H39 A40 P41 L45 T46 K47 V52 I259H39-I43 WeakPolarHBondContact CE1-CD1 3.35Å; H39-I43 VanDerWaalsContact NE2-CD1 3.34Å; H39-I43 WeakPolarHBondContact NE2-CD1 3.41Å; H39-I43 WeakPolarHBondContact O-CG1 3.36Å; H39-I43 PolarHBondContact O-N 3.2Å; A40-I43 PolarHBondContact O-N 2.86Å; P41-I43 PolarHBondContact O-N 3.25Å; I43-L45 VanDerWaalsContact C-N 3.29Å; I43-L45 PolarHBondContact O-N 3.02Å; I43-T46 PolarHBondContact O-N 3.32Å; I43-T46 PolarHBondContact O-OG1 2.92Å; I43-K47 PolarHBondContact O-N 3.33Å; I43-V52 HydrophobicContact CG2-CG2 4.34Å; I43-I259 HydrophobicContact CG1-CD1 3.83Å
44T86.4Confident86Confident35 Ų3557.5 Ų57.522%0.21533%0.331CS..Hα-helixtrans-62.9-37.9-179.3-56.70000111.7A40 P41 L42 T46 K47 L301A40-T44 PolarHBondContact O-N 3.42Å; A40-T44 PolarHBondContact O-OG1 3.34Å; P41-T44 WeakPolarHBondContact O-CB 3.41Å; P41-T44 PolarHBondContact O-N 2.97Å; P41-T44 VanDerWaalsContact O-N 3.1Å; L42-T44 VanDerWaalsContact C-N 3.27Å; L42-T44 PolarHBondContact O-N 2.87Å; T44-T46 PolarHBondContact O-N 3.1Å; T44-K47 WeakPolarHBondContact O-CB 3.25Å; T44-K47 PolarHBondContact O-N 2.92Å; T44-K47 VanDerWaalsContact O-N 3.17Å; T44-L301 HydrophobicContact CG2-CD1 3.75Å; T44-L301 HydrophobicContact CG2-CD2 4.2Å
45L87.2Confident85.5Confident86 Ų8654.5 Ų54.545%0.4532%0.318SS..Hα-helixtrans-64.2-24.5173-70.7174.8000114P41 L42 I43 K47 L300 L301P41-L45 WeakPolarHBondContact O-CG 3.43Å; P41-L45 PolarHBondContact O-N 2.96Å; L42-L45 PolarHBondContact O-N 3.34Å; I43-L45 VanDerWaalsContact C-N 3.29Å; I43-L45 PolarHBondContact O-N 3.02Å; L45-K47 VanDerWaalsContact C-N 3.32Å; L45-L300 HydrophobicContact CD1-CD1 4.09Å; L45-L301 HydrophobicContact CD2-CD2 3.56Å; L45-L301 HydrophobicContact CG-CD2 4.04Å
46T86.5Confident84.9Confident7 Ų757.3 Ų57.34%0.04334%0.339CS..Hα-helixtrans-80.5-12.2176.664.90000113.5L42 I43 T44 V48 P53 F54 V255 V256 I259L42-T46 WeakPolarHBondContact O-CG2 3.38Å; L42-T46 PolarHBondContact O-N 2.93Å; I43-T46 PolarHBondContact O-N 3.32Å; I43-T46 PolarHBondContact O-OG1 2.92Å; T44-T46 PolarHBondContact O-N 3.1Å; T46-V48 PolarHBondContact O-N 3.47Å; T46-P53 WeakPolarHBondContact O-CD 3.28Å; T46-P53 WeakPolarHBondContact O-CG 3.21Å; T46-F54 HydrophobicContact CG2-CE1 4.44Å; T46-V255 HydrophobicContact CG2-CB 3.89Å; T46-V255 HydrophobicContact CG2-CG1 3.66Å; T46-V256 HydrophobicContact CG2-CG2 3.88Å; T46-I259 HydrophobicContact CG2-CD1 3.93Å
47K84.7Confident84.4Confident93 Ų9355.3 Ų55.340%0.40434%0.337SS..  trans-71.3128.5-176.3-67.9178.8-179.9176.30111I43 T44 L45 R51 V52I43-K47 PolarHBondContact O-N 3.33Å; T44-K47 WeakPolarHBondContact O-CB 3.25Å; T44-K47 PolarHBondContact O-N 2.92Å; T44-K47 VanDerWaalsContact O-N 3.17Å; L45-K47 VanDerWaalsContact C-N 3.32Å; K47-R51 CarbonylContact C-O 3.55Å; K47-R51 VanDerWaalsContact CA-O 3.26Å; K47-R51 WeakPolarHBondContact CA-O 3Å; K47-V52 HydrophobicContact CG-CG2 4.08Å
48V77.7Confident84.1Confident113 Ų11355.3 Ų55.369%0.68534%0.336SS*.BIsolated β-bridgetrans-114.1121.6172.3-177.40000107.4T46 G50 R51T46-V48 PolarHBondContact O-N 3.47Å; V48-G50 PolarHBondContact O-N 3.48Å; V48-R51 PolarHBondContact N-O 3.42Å; V48-R51 PolarHBondContact O-N 3.18Å
49G71.2Confident83.9Confident82 Ų8254.5 Ų54.585%0.84533%0.331SS*.THydrogen-bonded Turntrans61.530.5-175.500000114R51G49-R51 PolarHBondContact O-N 3.21Å
50G71.7Confident83.8Confident63 Ų6354 Ų5465%0.64933%0.332SS*.THydrogen-bonded Turntrans77.9-3.5-178.700000115.3V48V48-G50 PolarHBondContact O-N 3.48Å
51R74.8Confident83.9Confident206 Ų20652.1 Ų52.178%0.77732%0.316SS*.BIsolated β-bridgetrans-107.2146.9178.5-63.6-175.5-179.4-175.20.7111.2K47 V48 G49K47-R51 CarbonylContact C-O 3.55Å; K47-R51 VanDerWaalsContact CA-O 3.26Å; K47-R51 WeakPolarHBondContact CA-O 3Å; V48-R51 PolarHBondContact N-O 3.42Å; V48-R51 PolarHBondContact O-N 3.18Å; G49-R51 PolarHBondContact O-N 3.21Å
52V81.6Confident84Confident54 Ų5453.1 Ų53.133%0.32732%0.321SS..  trans-77.4123.1172.8-179.70000107.5I43 K47 F54I43-V52 HydrophobicContact CG2-CG2 4.34Å; K47-V52 HydrophobicContact CG-CG2 4.08Å; V52-F54 VanDerWaalsContact C-N 3.27Å; V52-F54 HydrophobicContact CG1-CD1 3.48Å; V52-F54 VanDerWaalsContact CG1-CD1 3.48Å; V52-F54 HydrophobicContact CG1-CD2 4.01Å; V52-F54 HydrophobicContact CG1-CE1 3.25Å; V52-F54 HydrophobicContact CG1-CE2 3.8Å; V52-F54 HydrophobicContact CG1-CG 3.86Å; V52-F54 HydrophobicContact CG1-CZ 3.43Å; V52-F54 VanDerWaalsContact CG1-CZ 3.43Å; V52-F54 PolarHBondContact O-N 2.72Å
53P81.3Confident84.2Confident52 Ų5252.4 Ų52.434%0.33832%0.317SS..SBendtrans-78.5-10.3-171.531.7-36.9000113.5T46T46-P53 WeakPolarHBondContact O-CD 3.28Å; T46-P53 WeakPolarHBondContact O-CG 3.21Å
54F84.6Confident84.4Confident16 Ų1651.6 Ų51.67%0.0731%0.312CS..SBendtrans-111.6153.5-178.363.1-95.7000112T46 V52 S56 C59 E250 Y252 V256T46-F54 HydrophobicContact CG2-CE1 4.44Å; V52-F54 VanDerWaalsContact C-N 3.27Å; V52-F54 HydrophobicContact CG1-CD1 3.48Å; V52-F54 VanDerWaalsContact CG1-CD1 3.48Å; V52-F54 HydrophobicContact CG1-CD2 4.01Å; V52-F54 HydrophobicContact CG1-CE1 3.25Å; V52-F54 HydrophobicContact CG1-CE2 3.8Å; V52-F54 HydrophobicContact CG1-CG 3.86Å; V52-F54 HydrophobicContact CG1-CZ 3.43Å; V52-F54 VanDerWaalsContact CG1-CZ 3.43Å; V52-F54 PolarHBondContact O-N 2.72Å; F54-S56 PolarHBondContact O-N 2.94Å; F54-C59 HydrophobicContact CD2-CB 3.93Å; F54-C59 HydrophobicContact CE2-CB 3.84Å; F54-E250 WeakPolarHBondContact CA-O 3.44Å; F54-Y252 HydrophobicContact CB-CD2 3.95Å; F54-Y252 HydrophobicContact CB-CE2 3.73Å; F54-V256 HydrophobicContact CD1-CB 4.43Å; F54-V256 HydrophobicContact CD1-CG1 3.97Å; F54-V256 HydrophobicContact CD1-CG2 3.5Å; F54-V256 VanDerWaalsContact CD1-CG2 3.5Å; F54-V256 HydrophobicContact CD2-CG1 4.42Å; F54-V256 HydrophobicContact CE1-CG1 4.12Å; F54-V256 HydrophobicContact CE1-CG2 3.69Å; F54-V256 HydrophobicContact CG-CG1 4.13Å; F54-V256 HydrophobicContact CG-CG2 4.35Å; F54-V256 HydrophobicContact CZ-CG1 4.43Å
55S84Confident84.8Confident30 Ų3053 Ų5321%0.2132%0.318CS..  trans-70.2122.5173.7176.20000111.8S57 S58 C59S55-S57 PolarHBondContact O-N 3.45Å; S55-S57 PolarHBondContact OG-N 3.38Å; S55-S58 PolarHBondContact O-N 3.34Å; S55-C59 PolarHBondContact O-N 3.47Å; S55-C59 VanDerWaalsContact O-N 3.11Å
56S82.9Confident85.2Confident85 Ų8550.7 Ų50.759%0.59431%0.308SS*.Hα-helixtrans-57.9-34.9175.1-61.10000112.5F54 C59 V60F54-S56 PolarHBondContact O-N 2.94Å; S56-C59 PolarHBondContact O-N 2.87Å; S56-V60 VanDerWaalsContact O-CG2 3.31Å; S56-V60 WeakPolarHBondContact O-CG2 3.37Å; S56-V60 PolarHBondContact O-N 2.86Å; S56-V60 VanDerWaalsContact O-N 3.09Å
57S83.4Confident85.7Confident35 Ų3551.6 Ų51.625%0.24531%0.311CS..Hα-helixtrans-69.2-45.9-179.5-1780000111.6S55 C59 V60 L61 H238S55-S57 PolarHBondContact O-N 3.45Å; S55-S57 PolarHBondContact OG-N 3.38Å; S57-C59 VanDerWaalsContact C-N 3.29Å; S57-C59 PolarHBondContact O-N 2.7Å; S57-V60 PolarHBondContact O-N 3.46Å; S57-L61 PolarHBondContact O-N 2.87Å; S57-H238 WeakPolarHBondContact OG-CB 3.3Å; S57-H238 PolarHBondContact OG-ND1 3.44Å
58S87.8Confident86.1Confident2 Ų248.8 Ų48.81%0.01430%0.3CS..Hα-helixtrans-61.5-38.7175.2-50.50000111.8S55 L61 L62 F248S55-S58 PolarHBondContact O-N 3.34Å; S58-L61 WeakPolarHBondContact O-CB 3.3Å; S58-L61 PolarHBondContact O-N 3.33Å; S58-L62 WeakPolarHBondContact O-CG 3.44Å; S58-L62 PolarHBondContact O-N 3.25Å; S58-F248 WeakPolarHBondContact CB-O 3.2Å; S58-F248 WeakPolarHBondContact OG-CD2 3.07Å; S58-F248 PolarHBondContact OG-O 2.97Å
59C89Confident87Confident9 Ų948.3 Ų48.36%0.06129%0.293CS..Hα-helixtrans-64.6-45178.7-175.90000111.6F54 S55 S56 S57 L61 L62 I63 Y252F54-C59 HydrophobicContact CD2-CB 3.93Å; F54-C59 HydrophobicContact CE2-CB 3.84Å; S55-C59 PolarHBondContact O-N 3.47Å; S55-C59 VanDerWaalsContact O-N 3.11Å; S56-C59 PolarHBondContact O-N 2.87Å; S57-C59 VanDerWaalsContact C-N 3.29Å; S57-C59 PolarHBondContact O-N 2.7Å; C59-L61 VanDerWaalsContact C-N 3.33Å; C59-L61 PolarHBondContact O-N 3.19Å; C59-L62 PolarHBondContact O-N 2.92Å; C59-I63 WeakPolarHBondContact O-CD1 3.3Å; C59-I63 VanDerWaalsContact O-CG1 3.26Å; C59-I63 WeakPolarHBondContact O-CG1 3.34Å; C59-I63 PolarHBondContact O-N 3.1Å; C59-Y252 WeakPolarHBondContact CA-OH 3.44Å; C59-Y252 WeakPolarHBondContact CB-OH 3.35Å; C59-Y252 PolarHBondContact N-OH 3.46Å
60V89Confident88.1Confident49 Ų4947.3 Ų47.330%0.29727%0.271SS..Hα-helixtrans-61.9-40.9175.6173.30000111.4S56 S57 I63 E64 N234S56-V60 VanDerWaalsContact O-CG2 3.31Å; S56-V60 WeakPolarHBondContact O-CG2 3.37Å; S56-V60 PolarHBondContact O-N 2.86Å; S56-V60 VanDerWaalsContact O-N 3.09Å; S57-V60 PolarHBondContact O-N 3.46Å; V60-I63 WeakPolarHBondContact O-CB 3.41Å; V60-I63 PolarHBondContact O-N 2.64Å; V60-E64 PolarHBondContact O-N 3.31Å; V60-N234 VanDerWaalsContact CG1-OD1 3.31Å; V60-N234 WeakPolarHBondContact CG1-OD1 3.29Å
61L89.9Confident89.1Confident5 Ų544.4 Ų44.43%0.02624%0.24CC..Hα-helixtrans-60.8-47.6174.9-78.4174.4000112.4S57 S58 C59 I63 E64 I65 L231 N234 L235 H238 F248S57-L61 PolarHBondContact O-N 2.87Å; S58-L61 WeakPolarHBondContact O-CB 3.3Å; S58-L61 PolarHBondContact O-N 3.33Å; C59-L61 VanDerWaalsContact C-N 3.33Å; C59-L61 PolarHBondContact O-N 3.19Å; L61-I63 VanDerWaalsContact C-N 3.28Å; L61-I63 PolarHBondContact O-N 3.08Å; L61-E64 PolarHBondContact O-N 3.35Å; L61-I65 VanDerWaalsContact O-CG1 3.3Å; L61-I65 WeakPolarHBondContact O-CG1 3.47Å; L61-I65 PolarHBondContact O-N 3.22Å; L61-L231 HydrophobicContact CD2-CD1 3.86Å; L61-N234 HydrophobicContact CD2-CB 3.67Å; L61-N234 HydrophobicContact CG-CB 4.4Å; L61-L235 HydrophobicContact CD2-CB 4.22Å; L61-H238 HydrophobicContact CD1-CB 3.63Å; L61-F248 HydrophobicContact CB-CZ 4.32Å; L61-F248 HydrophobicContact CD1-CE2 3.94Å; L61-F248 HydrophobicContact CD1-CZ 4.44Å
62L92.4Very high90Very high21 Ų2137.7 Ų37.711%0.1122%0.219CC..Hα-helixtrans-61.9-36.4177.1-75.7172.6000112.4S58 C59 T66 F248 L249 Y252 W257 V260S58-L62 WeakPolarHBondContact O-CG 3.44Å; S58-L62 PolarHBondContact O-N 3.25Å; C59-L62 PolarHBondContact O-N 2.92Å; L62-T66 VanDerWaalsContact O-CB 3.28Å; L62-T66 WeakPolarHBondContact O-CB 3.19Å; L62-T66 PolarHBondContact O-N 3.44Å; L62-T66 PolarHBondContact O-OG1 3.37Å; L62-F248 HydrophobicContact CD1-CE1 4.37Å; L62-F248 HydrophobicContact CD2-CE1 4.16Å; L62-F248 HydrophobicContact CG-CE1 4.1Å; L62-F248 HydrophobicContact CG-CZ 4.31Å; L62-L249 HydrophobicContact CD1-CD2 3.91Å; L62-Y252 HydrophobicContact CD1-CD1 4.34Å; L62-Y252 HydrophobicContact CD1-CE1 3.41Å; L62-Y252 VanDerWaalsContact CD1-CE1 3.41Å; L62-W257 HydrophobicContact CD1-CH2 4.18Å; L62-W257 HydrophobicContact CD1-CZ3 4.4Å; L62-W257 HydrophobicContact CD2-CH2 4.45Å; L62-V260 HydrophobicContact CB-CG1 4.08Å; L62-V260 HydrophobicContact CB-CG2 4.38Å
63I93.5Very high90.5Very high17 Ų1737.3 Ų37.39%0.08722%0.222CC..Hα-helixtrans-62.3-47.9173.9-71.2162.7000110.6C59 V60 L61 T66 K67 V260 Q263C59-I63 WeakPolarHBondContact O-CD1 3.3Å; C59-I63 VanDerWaalsContact O-CG1 3.26Å; C59-I63 WeakPolarHBondContact O-CG1 3.34Å; C59-I63 PolarHBondContact O-N 3.1Å; V60-I63 WeakPolarHBondContact O-CB 3.41Å; V60-I63 PolarHBondContact O-N 2.64Å; L61-I63 VanDerWaalsContact C-N 3.28Å; L61-I63 PolarHBondContact O-N 3.08Å; I63-T66 PolarHBondContact O-N 3.42Å; I63-K67 HydrophobicContact CG2-CD 4.35Å; I63-K67 VanDerWaalsContact O-CG 3.32Å; I63-K67 WeakPolarHBondContact O-CG 3.27Å; I63-K67 PolarHBondContact O-N 3.21Å; I63-V260 HydrophobicContact CG1-CB 4.26Å; I63-V260 HydrophobicContact CG1-CG1 4.05Å; I63-V260 HydrophobicContact CG1-CG2 4.28Å; I63-Q263 HydrophobicContact CD1-CB 3.61Å; I63-Q263 HydrophobicContact CD1-CG 4.09Å; I63-Q263 HydrophobicContact CG1-CB 3.97Å; I63-Q263 HydrophobicContact CG2-CB 4.12Å
64E93.3Very high91Very high24 Ų2437.8 Ų37.811%0.11222%0.224CC..Hα-helixtrans-65.9-41.4178.9-68.7-57.3127.900112.2V60 L61 T66 K67 L68 L231V60-E64 PolarHBondContact O-N 3.31Å; L61-E64 PolarHBondContact O-N 3.35Å; E64-T66 VanDerWaalsContact C-N 3.34Å; E64-T66 PolarHBondContact O-N 3.08Å; E64-K67 PolarHBondContact O-N 3.25Å; E64-K67 IonicContact OE1-NZ 2.66Å; E64-K67 PolarHBondContact OE1-NZ 3.12Å; E64-L68 WeakPolarHBondContact O-CB 3.46Å; E64-L68 PolarHBondContact O-N 3.06Å; E64-L231 HydrophobicContact CB-CB 4.43Å; E64-L231 HydrophobicContact CB-CD1 4.37Å
65I94.6Very high91.2Very high63 Ų6337 Ų3732%0.32322%0.22SC..Hα-helixtrans-59.3-46.6173.2-68.4168.1000110.2L61 K67 L68 L69 L231L61-I65 VanDerWaalsContact O-CG1 3.3Å; L61-I65 WeakPolarHBondContact O-CG1 3.47Å; L61-I65 PolarHBondContact O-N 3.22Å; I65-K67 PolarHBondContact O-N 2.88Å; I65-L68 WeakPolarHBondContact O-CB 3.5Å; I65-L68 PolarHBondContact O-N 2.85Å; I65-L69 HydrophobicContact CG2-CD1 3.92Å; I65-L69 HydrophobicContact CG2-CG 4.27Å; I65-L69 WeakPolarHBondContact O-CG 3.35Å; I65-L69 PolarHBondContact O-N 3.43Å; I65-L231 HydrophobicContact CD1-CD1 4.33Å; I65-L231 HydrophobicContact CG1-CD1 3.68Å; I65-L231 HydrophobicContact CG1-CD2 4.21Å
66T95.9Very high91.5Very high39 Ų3940 Ų4024%0.23923%0.233CC..Hα-helixtrans-62.3-43.8179.7-58.50000111.2L62 I63 E64 L68 L69 V70 A264L62-T66 VanDerWaalsContact O-CB 3.28Å; L62-T66 WeakPolarHBondContact O-CB 3.19Å; L62-T66 PolarHBondContact O-N 3.44Å; L62-T66 PolarHBondContact O-OG1 3.37Å; I63-T66 PolarHBondContact O-N 3.42Å; E64-T66 VanDerWaalsContact C-N 3.34Å; E64-T66 PolarHBondContact O-N 3.08Å; T66-L68 VanDerWaalsContact C-N 3.32Å; T66-L68 PolarHBondContact O-N 3.44Å; T66-L69 PolarHBondContact O-N 2.94Å; T66-V70 HydrophobicContact CG2-CG2 4.35Å; T66-V70 WeakPolarHBondContact O-CB 3.49Å; T66-V70 VanDerWaalsContact O-CG2 3.28Å; T66-V70 WeakPolarHBondContact O-CG2 3.49Å; T66-V70 PolarHBondContact O-N 3.15Å; T66-A264 HydrophobicContact CG2-CB 3.63Å
67K95.7Very high91.8Very high25 Ų2543.3 Ų43.311%0.10924%0.244CC..Hα-helixtrans-60.9-41.2175-71.6175.2-164.3162.40112I63 E64 I65 S71 Y227 A264 L268I63-K67 HydrophobicContact CG2-CD 4.35Å; I63-K67 VanDerWaalsContact O-CG 3.32Å; I63-K67 WeakPolarHBondContact O-CG 3.27Å; I63-K67 PolarHBondContact O-N 3.21Å; E64-K67 PolarHBondContact O-N 3.25Å; E64-K67 IonicContact OE1-NZ 2.66Å; E64-K67 PolarHBondContact OE1-NZ 3.12Å; I65-K67 PolarHBondContact O-N 2.88Å; K67-S71 VanDerWaalsContact O-CB 3.25Å; K67-S71 WeakPolarHBondContact O-CB 3.24Å; K67-S71 PolarHBondContact O-N 3.35Å; K67-S71 PolarHBondContact O-OG 2.88Å; K67-Y227 HydrophobicContact CB-CD1 4.25Å; K67-Y227 HydrophobicContact CB-CD2 3.63Å; K67-Y227 HydrophobicContact CB-CE1 4.35Å; K67-Y227 HydrophobicContact CB-CE2 3.7Å; K67-Y227 HydrophobicContact CB-CG 3.93Å; K67-Y227 HydrophobicContact CD-CD1 3.98Å; K67-Y227 HydrophobicContact CD-CE1 3.68Å; K67-Y227 HydrophobicContact CD-CE2 4.36Å; K67-Y227 HydrophobicContact CD-CG 4.49Å; K67-Y227 HydrophobicContact CG-CE2 4.4Å; K67-A264 HydrophobicContact CG-CB 3.88Å; K67-L268 HydrophobicContact CG-CG 4.46Å
68L94.6Very high91.9Very high35 Ų3545.4 Ų45.418%0.18326%0.255CS..Hα-helixtrans-63.3-49.1177.7-174.272.5000111E64 I65 T66 S71 L72 L224 V228 L231E64-L68 WeakPolarHBondContact O-CB 3.46Å; E64-L68 PolarHBondContact O-N 3.06Å; I65-L68 WeakPolarHBondContact O-CB 3.5Å; I65-L68 PolarHBondContact O-N 2.85Å; T66-L68 VanDerWaalsContact C-N 3.32Å; T66-L68 PolarHBondContact O-N 3.44Å; L68-S71 PolarHBondContact O-N 2.95Å; L68-L72 WeakPolarHBondContact O-CB 3.28Å; L68-L72 PolarHBondContact O-N 3.49Å; L68-L224 HydrophobicContact CD1-CD1 3.52Å; L68-L224 HydrophobicContact CD1-CG 4.1Å; L68-L224 HydrophobicContact CG-CD1 4.29Å; L68-V228 HydrophobicContact CD1-CG2 3.61Å; L68-L231 HydrophobicContact CD2-CD2 4.08Å
69L95.4Very high91.3Very high103 Ų10347.8 Ų47.854%0.53928%0.28SS..Hα-helixtrans-61.4-45.7178.6-70176.1000111.9I65 T66 S71 L72 A73I65-L69 HydrophobicContact CG2-CD1 3.92Å; I65-L69 HydrophobicContact CG2-CG 4.27Å; I65-L69 WeakPolarHBondContact O-CG 3.35Å; I65-L69 PolarHBondContact O-N 3.43Å; T66-L69 PolarHBondContact O-N 2.94Å; L69-S71 VanDerWaalsContact C-N 3.34Å; L69-S71 PolarHBondContact O-N 3.5Å; L69-L72 PolarHBondContact O-N 3.45Å; L69-A73 VanDerWaalsContact O-CB 3.31Å; L69-A73 WeakPolarHBondContact O-CB 3.43Å; L69-A73 PolarHBondContact O-N 3.45Å
70V95.6Very high90.5Very high61 Ų6150.2 Ų50.237%0.3729%0.292SS..Hα-helixtrans-65.9-38.2177.6174.40000111.2T66 A73 T74 L268T66-V70 HydrophobicContact CG2-CG2 4.35Å; T66-V70 WeakPolarHBondContact O-CB 3.49Å; T66-V70 VanDerWaalsContact O-CG2 3.28Å; T66-V70 WeakPolarHBondContact O-CG2 3.49Å; T66-V70 PolarHBondContact O-N 3.15Å; V70-A73 PolarHBondContact O-N 3.25Å; V70-T74 WeakPolarHBondContact O-CB 3.26Å; V70-T74 PolarHBondContact O-N 2.91Å; V70-T74 PolarHBondContact O-OG1 3.21Å; V70-L268 HydrophobicContact CB-CD1 3.85Å; V70-L268 HydrophobicContact CG1-CD1 3.44Å; V70-L268 VanDerWaalsContact CG1-CD1 3.44Å
71S92.9Very high89.7Confident2 Ų251 Ų511%0.01429%0.294CS..Hα-helixtrans-65.9-42.1176.5-60.30000111.7K67 L68 L69 T74 L75 Y227 L268K67-S71 VanDerWaalsContact O-CB 3.25Å; K67-S71 WeakPolarHBondContact O-CB 3.24Å; K67-S71 PolarHBondContact O-N 3.35Å; K67-S71 PolarHBondContact O-OG 2.88Å; L68-S71 PolarHBondContact O-N 2.95Å; L69-S71 VanDerWaalsContact C-N 3.34Å; L69-S71 PolarHBondContact O-N 3.5Å; S71-T74 PolarHBondContact O-N 2.89Å; S71-L75 WeakPolarHBondContact O-CB 3.34Å; S71-L75 PolarHBondContact O-N 3.43Å; S71-Y227 WeakPolarHBondContact OG-CE2 3.32Å; S71-L268 WeakPolarHBondContact OG-CD2 3.38Å
72L92.4Very high88.6Confident65 Ų6555 Ų5534%0.3432%0.323SS..Hα-helixtrans-64.3-48175.1-178.861.8000111.3L68 L69 T74 L75 L76 L224L68-L72 WeakPolarHBondContact O-CB 3.28Å; L68-L72 PolarHBondContact O-N 3.49Å; L69-L72 PolarHBondContact O-N 3.45Å; L72-T74 VanDerWaalsContact C-N 3.31Å; L72-T74 PolarHBondContact O-N 3.39Å; L72-L75 WeakPolarHBondContact O-CB 3.45Å; L72-L75 PolarHBondContact O-N 2.9Å; L72-L75 VanDerWaalsContact O-N 3.13Å; L72-L76 HydrophobicContact CG-CD1 4.22Å; L72-L76 WeakPolarHBondContact O-CG 3.31Å; L72-L76 PolarHBondContact O-N 3.32Å; L72-L224 HydrophobicContact CB-CD1 4.02Å; L72-L224 HydrophobicContact CD1-CD1 4.45Å
73A92.9Very high87.5Confident45 Ų4555.3 Ų55.337%0.37233%0.329SS..Hα-helixtrans-58.3-43.9176.300000111.4L69 V70 L75 L76 L77L69-A73 VanDerWaalsContact O-CB 3.31Å; L69-A73 WeakPolarHBondContact O-CB 3.43Å; L69-A73 PolarHBondContact O-N 3.45Å; V70-A73 PolarHBondContact O-N 3.25Å; A73-L75 VanDerWaalsContact C-N 3.32Å; A73-L75 PolarHBondContact O-N 3.01Å; A73-L76 PolarHBondContact O-N 3.49Å; A73-L77 WeakPolarHBondContact O-CB 3.13Å; A73-L77 VanDerWaalsContact O-CG 3.24Å; A73-L77 WeakPolarHBondContact O-CG 3.3Å; A73-L77 PolarHBondContact O-N 3.38Å
74T91Very high86.3Confident62 Ų6258 Ų5838%0.3834%0.343SS..Hα-helixtrans-61.1-42.1176.2-55.20000111.4V70 S71 L72 L77 T78V70-T74 WeakPolarHBondContact O-CB 3.26Å; V70-T74 PolarHBondContact O-N 2.91Å; V70-T74 PolarHBondContact O-OG1 3.21Å; S71-T74 PolarHBondContact O-N 2.89Å; L72-T74 VanDerWaalsContact C-N 3.31Å; L72-T74 PolarHBondContact O-N 3.39Å; T74-L77 PolarHBondContact O-N 2.9Å; T74-T78 WeakPolarHBondContact O-CG2 3.44Å; T74-T78 PolarHBondContact O-N 3.5Å; T74-T78 PolarHBondContact O-OG1 3.16Å
75L89.3Confident85.1Confident0 Ų067.2 Ų67.20%038%0.376CS..Hα-helixtrans-65.1-39.3178.1-174.566.7000112.6S71 L72 A73 T78 G79 D80 L84 P218 S220 L221 L224S71-L75 WeakPolarHBondContact O-CB 3.34Å; S71-L75 PolarHBondContact O-N 3.43Å; L72-L75 WeakPolarHBondContact O-CB 3.45Å; L72-L75 PolarHBondContact O-N 2.9Å; L72-L75 VanDerWaalsContact O-N 3.13Å; A73-L75 VanDerWaalsContact C-N 3.32Å; A73-L75 PolarHBondContact O-N 3.01Å; L75-T78 PolarHBondContact O-OG1 2.99Å; L75-G79 PolarHBondContact O-N 3.13Å; L75-D80 HydrophobicContact CD1-CB 3.8Å; L75-L84 HydrophobicContact CD2-CD1 3.51Å; L75-L84 HydrophobicContact CD2-CD2 4.33Å; L75-L84 HydrophobicContact CD2-CG 3.87Å; L75-L84 HydrophobicContact CG-CD1 4.26Å; L75-P218 HydrophobicContact CD1-CG 4.46Å; L75-S220 WeakPolarHBondContact CD1-OG 3.19Å; L75-L221 HydrophobicContact CD1-CB 4.22Å; L75-L221 HydrophobicContact CD2-CD1 3.93Å; L75-L224 HydrophobicContact CD2-CD2 4.5Å
76L89.6Confident83.9Confident93 Ų9366.8 Ų66.849%0.48738%0.382SS..Hα-helixtrans-65.3-42.2175-67.7170.7000111.3L72 A73 G79 L81L72-L76 HydrophobicContact CG-CD1 4.22Å; L72-L76 WeakPolarHBondContact O-CG 3.31Å; L72-L76 PolarHBondContact O-N 3.32Å; A73-L76 PolarHBondContact O-N 3.49Å; L76-G79 PolarHBondContact O-N 3.49Å; L76-L81 HydrophobicContact CD2-CD1 4.3Å; L76-L81 HydrophobicContact CD2-CD2 3.5Å; L76-L81 VanDerWaalsContact CD2-CD2 3.5Å; L76-L81 HydrophobicContact CD2-CG 4.31Å
77L89.5Confident82.6Confident155 Ų15570.8 Ų70.881%0.81241%0.409SS*.Hα-helixtrans-71-32.5179.9-69.7172.6000113.4A73 T74 G79A73-L77 WeakPolarHBondContact O-CB 3.13Å; A73-L77 VanDerWaalsContact O-CG 3.24Å; A73-L77 WeakPolarHBondContact O-CG 3.3Å; A73-L77 PolarHBondContact O-N 3.38Å; T74-L77 PolarHBondContact O-N 2.9Å; L77-G79 VanDerWaalsContact C-N 3.26Å; L77-G79 PolarHBondContact O-N 2.85Å
78T85.5Confident81.6Confident79 Ų7975.5 Ų75.549%0.48544%0.435SS..Hα-helixtrans-78.6-9.4175.957.10000113.5T74 L75 D80T74-T78 WeakPolarHBondContact O-CG2 3.44Å; T74-T78 PolarHBondContact O-N 3.5Å; T74-T78 PolarHBondContact O-OG1 3.16Å; L75-T78 PolarHBondContact O-OG1 2.99Å; T78-D80 WeakPolarHBondContact CB-OD2 3.37Å; T78-D80 PolarHBondContact O-N 3.35Å; T78-D80 PolarHBondContact OG1-OD2 3.47Å
79G76.4Confident80.9Confident51 Ų5176.7 Ų76.753%0.52645%0.446SS..THydrogen-bonded Turntrans74.210.9177.200000114.4L75 L76 L77 L81L75-G79 PolarHBondContact O-N 3.13Å; L76-G79 PolarHBondContact O-N 3.49Å; L77-G79 VanDerWaalsContact C-N 3.26Å; L77-G79 PolarHBondContact O-N 2.85Å; G79-L81 PolarHBondContact O-N 3.33Å
80D71.6Confident80.4Confident61 Ų6178.4 Ų78.433%0.32646%0.455SS..THydrogen-bonded Turntrans-76.829.9-179.9-63.5-52.7000112.8L75 T78 S82 A83 P218L75-D80 HydrophobicContact CD1-CB 3.8Å; T78-D80 WeakPolarHBondContact CB-OD2 3.37Å; T78-D80 PolarHBondContact O-N 3.35Å; T78-D80 PolarHBondContact OG1-OD2 3.47Å; D80-S82 PolarHBondContact O-N 3.24Å; D80-A83 WeakPolarHBondContact O-CB 3.5Å; D80-A83 PolarHBondContact O-N 2.83Å; D80-A83 VanDerWaalsContact O-N 3.1Å; D80-P218 HydrophobicContact CB-CG 4.31Å
81L71.9Confident79.9Confident64 Ų6479.5 Ų79.534%0.33547%0.47SS..THydrogen-bonded Turntrans-65.8-20.2-176.9-76.5174.2000113.6L76 G79 A83 L84 R85L76-L81 HydrophobicContact CD2-CD1 4.3Å; L76-L81 HydrophobicContact CD2-CD2 3.5Å; L76-L81 VanDerWaalsContact CD2-CD2 3.5Å; L76-L81 HydrophobicContact CD2-CG 4.31Å; G79-L81 PolarHBondContact O-N 3.33Å; L81-A83 PolarHBondContact O-N 3.4Å; L81-L84 HydrophobicContact CD2-CD1 3.53Å; L81-L84 PolarHBondContact O-N 2.9Å; L81-L84 VanDerWaalsContact O-N 3.14Å; L81-R85 PolarHBondContact O-N 3.08Å
82S67.8Low79.5Confident91 Ų9181.7 Ų81.764%0.63648%0.481SS*.Hα-helixtrans-58-31.117252.90000111.9D80 R85 A86D80-S82 PolarHBondContact O-N 3.24Å; S82-R85 PolarHBondContact O-N 3.44Å; S82-A86 PolarHBondContact O-N 2.96Å
83A67.6Low79.4Confident27 Ų2779.4 Ų79.422%0.22347%0.47CS..Hα-helixtrans-73.8-25.2178.300000113.5D80 L81 L221D80-A83 WeakPolarHBondContact O-CB 3.5Å; D80-A83 PolarHBondContact O-N 2.83Å; D80-A83 VanDerWaalsContact O-N 3.1Å; L81-A83 PolarHBondContact O-N 3.4Å; A83-L221 HydrophobicContact CB-CD2 3.69Å
84L69.8Low79.2Confident74 Ų7479.3 Ų79.339%0.38747%0.469SS..Hα-helixtrans-78.1-26.3173-80.9159000112.6L75 L81 L221 L224L75-L84 HydrophobicContact CD2-CD1 3.51Å; L75-L84 HydrophobicContact CD2-CD2 4.33Å; L75-L84 HydrophobicContact CD2-CG 3.87Å; L75-L84 HydrophobicContact CG-CD1 4.26Å; L81-L84 HydrophobicContact CD2-CD1 3.53Å; L81-L84 PolarHBondContact O-N 2.9Å; L81-L84 VanDerWaalsContact O-N 3.14Å; L84-L221 HydrophobicContact CD2-CD1 4.49Å; L84-L224 HydrophobicContact CD2-CD2 4.33Å
85R66.9Low79.3Confident217 Ų21777.8 Ų77.882%0.81946%0.461SS*.Hα-helixtrans-83.3-18178.8-67.7-177.4-179.8175.80.4113.1L81 S82L81-R85 PolarHBondContact O-N 3.08Å; S82-R85 PolarHBondContact O-N 3.44Å
86A69.4Low79.5Confident53 Ų5377.9 Ų77.944%0.43846%0.461SS..SBendtrans-68.1142174.400000110.2S82 L88S82-A86 PolarHBondContact O-N 2.96Å; A86-L88 PolarHBondContact O-N 2.75Å
87P69.6Low79.7Confident124 Ų12474.9 Ų74.981%0.80545%0.449SS*.  trans-58.6128.4177.322.8-31.6000110.4S89P87-S89 PolarHBondContact O-N 3.24Å
88L73.1Confident79.9Confident124 Ų12470.3 Ų70.365%0.64943%0.428SS*.  trans-64.4100.8177.8-84.1144000109.5A86 L90 V93 Y225A86-L88 PolarHBondContact O-N 2.75Å; L88-L90 PolarHBondContact O-N 3.26Å; L88-V93 HydrophobicContact CD2-CG2 3.52Å; L88-Y225 HydrophobicContact CD2-CE1 3.77Å
89S81.7Confident80.2Confident60 Ų6066.6 Ų66.642%0.4241%0.405SS..  trans-75.9121.9169.659.80000109.1P87 A91 L92 V93P87-S89 PolarHBondContact O-N 3.24Å; S89-A91 PolarHBondContact O-N 3.39Å; S89-A91 VanDerWaalsContact O-N 3.15Å; S89-L92 WeakPolarHBondContact O-CB 3.33Å; S89-L92 PolarHBondContact O-N 3.24Å; S89-L92 WeakPolarHBondContact OG-CB 3.03Å; S89-V93 PolarHBondContact O-N 3.25Å
90L83.6Confident80.9Confident139 Ų13964.5 Ų64.573%0.72838%0.383SS*.Hα-helixtrans-56.6-33.6179.5-172.565.6000111.5L88 L92 V93 A94L88-L90 PolarHBondContact O-N 3.26Å; L90-L92 PolarHBondContact O-N 2.94Å; L90-V93 PolarHBondContact O-N 3.25Å; L90-A94 HydrophobicContact CG-CB 4.41Å; L90-A94 WeakPolarHBondContact O-CB 3.45Å; L90-A94 PolarHBondContact O-N 2.89Å
91A84.9Confident81.9Confident84 Ų8464 Ų6469%0.69439%0.387SS*.Hα-helixtrans-61-28175.300000113.8S89 P95S89-A91 PolarHBondContact O-N 3.39Å; S89-A91 VanDerWaalsContact O-N 3.15Å; A91-P95 VanDerWaalsContact O-CD 3.29Å; A91-P95 WeakPolarHBondContact O-CD 3.38Å; A91-P95 WeakPolarHBondContact O-CG 3.41Å
92L85.7Confident83Confident47 Ų4762.4 Ų62.425%0.24638%0.379CS..Hα-helixtrans-82.1-36.7178.7-172.8124.1000111.4S89 L90 Y96 Q215 L217 Y225S89-L92 WeakPolarHBondContact O-CB 3.33Å; S89-L92 PolarHBondContact O-N 3.24Å; S89-L92 WeakPolarHBondContact OG-CB 3.03Å; L90-L92 PolarHBondContact O-N 2.94Å; L92-Y96 WeakPolarHBondContact O-CD2 3.18Å; L92-Y96 WeakPolarHBondContact O-CE2 3.03Å; L92-Q215 PolarHBondContact O-NE2 2.74Å; L92-L217 HydrophobicContact CD1-CD1 4.03Å; L92-L217 HydrophobicContact CD1-CD2 4.32Å; L92-L217 HydrophobicContact CD2-CD1 3.63Å; L92-L217 HydrophobicContact CG-CD1 3.91Å; L92-Y225 HydrophobicContact CD2-CE2 3.63Å
93V88.7Confident84.1Confident17 Ų1760.5 Ų60.510%0.10336%0.358CS..Hα-helixtrans-91.2-39.9-173.2-178.40000113.1L88 S89 L90 P95 Y96 Y225 F229L88-V93 HydrophobicContact CD2-CG2 3.52Å; S89-V93 PolarHBondContact O-N 3.25Å; L90-V93 PolarHBondContact O-N 3.25Å; V93-P95 VanDerWaalsContact C-N 3.32Å; V93-Y96 WeakPolarHBondContact O-CB 3.38Å; V93-Y96 WeakPolarHBondContact O-CD2 3.34Å; V93-Y96 PolarHBondContact O-N 3.5Å; V93-Y225 HydrophobicContact CG1-CD1 4.19Å; V93-Y225 HydrophobicContact CG1-CG 4.29Å; V93-Y225 HydrophobicContact CG2-CD1 4.22Å; V93-Y225 HydrophobicContact CG2-CD2 4.39Å; V93-Y225 HydrophobicContact CG2-CE1 4.01Å; V93-Y225 HydrophobicContact CG2-CE2 4.17Å; V93-Y225 HydrophobicContact CG2-CG 4.42Å; V93-F229 HydrophobicContact CG1-CE2 3.6Å; V93-F229 HydrophobicContact CG1-CZ 3.83Å; V93-F229 WeakPolarHBondContact O-CE2 3.27Å
94A89.8Confident85Confident43 Ų4359.6 Ų59.636%0.35535%0.351SS..Hα-helixtrans-53.6-36.3-17700000114.8L90 Y96 A97L90-A94 HydrophobicContact CG-CB 4.41Å; L90-A94 WeakPolarHBondContact O-CB 3.45Å; L90-A94 PolarHBondContact O-N 2.89Å; A94-Y96 PolarHBondContact O-N 2.93Å; A94-Y96 VanDerWaalsContact O-N 3.15Å; A94-A97 WeakPolarHBondContact O-CB 3.32Å; A94-A97 PolarHBondContact O-N 3.44Å; A94-A97 VanDerWaalsContact O-N 3.09Å
95P93.8Very high86Confident31 Ų3161.4 Ų61.420%0.20136%0.355CS..Hα-helixtrans-60.2-24.8176.7-25.135.6000114.3A91 V93 A97 P99 Y207 V211A91-P95 VanDerWaalsContact O-CD 3.29Å; A91-P95 WeakPolarHBondContact O-CD 3.38Å; A91-P95 WeakPolarHBondContact O-CG 3.41Å; V93-P95 VanDerWaalsContact C-N 3.32Å; P95-A97 VanDerWaalsContact C-N 3.33Å; P95-P99 WeakPolarHBondContact O-CD 3.25Å; P95-Y207 WeakPolarHBondContact O-CE1 3.24Å; P95-V211 HydrophobicContact CB-CG1 4.11Å; P95-V211 HydrophobicContact CB-CG2 4.04Å
96Y92.9Very high87.2Confident2 Ų251.4 Ų51.41%0.00832%0.318CS..Hα-helixtrans-77.2-18.8178.6-62.1-84.6000113L92 V93 A94 V98 P99 V211 L212 Q215 Q222 Y225 L226L92-Y96 WeakPolarHBondContact O-CD2 3.18Å; L92-Y96 WeakPolarHBondContact O-CE2 3.03Å; V93-Y96 WeakPolarHBondContact O-CB 3.38Å; V93-Y96 WeakPolarHBondContact O-CD2 3.34Å; V93-Y96 PolarHBondContact O-N 3.5Å; A94-Y96 PolarHBondContact O-N 2.93Å; A94-Y96 VanDerWaalsContact O-N 3.15Å; Y96-V98 VanDerWaalsContact C-N 3.33Å; Y96-P99 WeakPolarHBondContact O-CD 3.38Å; Y96-V211 HydrophobicContact CD1-CG1 3.64Å; Y96-V211 HydrophobicContact CD2-CG1 4.37Å; Y96-V211 HydrophobicContact CE1-CG1 3.39Å; Y96-V211 HydrophobicContact CE2-CG1 4.16Å; Y96-V211 HydrophobicContact CG-CG1 4.12Å; Y96-L212 HydrophobicContact CE1-CD2 4.35Å; Y96-Q215 PolarHBondContact OH-OE1 3.36Å; Y96-Q222 HydrophobicContact CE1-CB 3.78Å; Y96-Q222 HydrophobicContact CE1-CG 4.23Å; Y96-Q222 VanDerWaalsContact OH-CG 3.3Å; Y96-Q222 WeakPolarHBondContact OH-CG 3.45Å; Y96-Q222 PolarHBondContact OH-NE2 3.28Å; Y96-Y225 AromaticContact CD2-CD2 3.98Å; Y96-Y225 HydrophobicContact CD2-CD2 3.98Å; Y96-Y225 HydrophobicContact CD2-CG 4.32Å; Y96-Y225 AromaticContact CE2-CD2 3.82Å; Y96-Y225 HydrophobicContact CE2-CD2 3.82Å; Y96-L226 HydrophobicContact CD1-CB 4.42Å
97A92.8Very high88.1Confident29 Ų2952.9 Ų52.924%0.2432%0.319CS..Hα-helixtrans-67.7-34175.800000112.2A94 P95 A100 A101 F229A94-A97 WeakPolarHBondContact O-CB 3.32Å; A94-A97 PolarHBondContact O-N 3.44Å; A94-A97 VanDerWaalsContact O-N 3.09Å; P95-A97 VanDerWaalsContact C-N 3.33Å; A97-A100 PolarHBondContact O-N 3.04Å; A97-A101 WeakPolarHBondContact O-CB 3.49Å; A97-A101 PolarHBondContact O-N 2.83Å; A97-F229 HydrophobicContact CB-CD1 3.79Å; A97-F229 HydrophobicContact CB-CD2 3.91Å; A97-F229 HydrophobicContact CB-CE1 3.82Å; A97-F229 HydrophobicContact CB-CE2 3.93Å; A97-F229 HydrophobicContact CB-CG 3.85Å; A97-F229 HydrophobicContact CB-CZ 3.89Å
98V94Very high88.9Confident59 Ų5951.2 Ų51.236%0.35830%0.303SS..Hα-helixtrans-64-51.7-177.3175.60000111.8Y96 A100 A101 L102 Y207Y96-V98 VanDerWaalsContact C-N 3.33Å; V98-A100 VanDerWaalsContact C-N 3.32Å; V98-A100 PolarHBondContact O-N 3.23Å; V98-A101 PolarHBondContact O-N 2.96Å; V98-L102 HydrophobicContact CG1-CD1 3.92Å; V98-L102 HydrophobicContact CG1-CG 4.37Å; V98-L102 VanDerWaalsContact O-CG 3.29Å; V98-L102 WeakPolarHBondContact O-CG 3.06Å; V98-L102 PolarHBondContact O-N 3.41Å; V98-Y207 HydrophobicContact CB-CD1 4.32Å; V98-Y207 HydrophobicContact CB-CE1 3.74Å; V98-Y207 HydrophobicContact CG1-CD1 4.13Å; V98-Y207 HydrophobicContact CG1-CD2 4.33Å; V98-Y207 HydrophobicContact CG1-CE1 3.85Å; V98-Y207 HydrophobicContact CG1-CE2 4.1Å; V98-Y207 HydrophobicContact CG1-CG 4.34Å; V98-Y207 HydrophobicContact CG2-CE1 4.48Å
99P93Very high89.6Confident1 Ų145.8 Ų45.81%0.00627%0.274CS..Hα-helixtrans-53.1-45.1170.4-32.738.4000114.3P95 Y96 A101 L102 Y103 Y207 T208 L226P95-P99 WeakPolarHBondContact O-CD 3.25Å; Y96-P99 WeakPolarHBondContact O-CD 3.38Å; P99-A101 PolarHBondContact O-N 3.48Å; P99-L102 PolarHBondContact O-N 3.42Å; P99-Y103 HydrophobicContact CB-CD2 4.47Å; P99-Y103 HydrophobicContact CB-CE2 4.35Å; P99-Y103 WeakPolarHBondContact O-CD2 3.33Å; P99-Y103 PolarHBondContact O-N 2.87Å; P99-Y207 HydrophobicContact CG-CD1 3.65Å; P99-Y207 HydrophobicContact CG-CE1 4.2Å; P99-T208 WeakPolarHBondContact CB-OG1 3.34Å; P99-L226 HydrophobicContact CB-CD1 3.61Å; P99-L226 HydrophobicContact CG-CD1 4.33Å
100A91.2Very high89.9Confident8 Ų844.6 Ų44.67%0.06627%0.265CS..Hα-helixtrans-61.5-45.6-178.700000111.1A97 V98 Y103 A104 F229 I233A97-A100 PolarHBondContact O-N 3.04Å; V98-A100 VanDerWaalsContact C-N 3.32Å; V98-A100 PolarHBondContact O-N 3.23Å; A100-Y103 PolarHBondContact O-N 2.83Å; A100-A104 WeakPolarHBondContact O-CB 3.43Å; A100-A104 PolarHBondContact O-N 3.38Å; A100-F229 HydrophobicContact CB-CB 3.6Å; A100-I233 HydrophobicContact CB-CD1 4.1Å
101A91.9Very high90Very high49 Ų4942.9 Ų42.941%0.40526%0.26SS..Hα-helixtrans-63-43.617500000112.5A97 V98 P99 A104 F105 I233A97-A101 WeakPolarHBondContact O-CB 3.49Å; A97-A101 PolarHBondContact O-N 2.83Å; V98-A101 PolarHBondContact O-N 2.96Å; P99-A101 PolarHBondContact O-N 3.48Å; A101-A104 PolarHBondContact O-N 2.88Å; A101-F105 VanDerWaalsContact O-CB 3.3Å; A101-F105 WeakPolarHBondContact O-CB 3.32Å; A101-F105 PolarHBondContact O-N 3.01Å; A101-I233 HydrophobicContact CB-CD1 4.1Å
102L94.4Very high90.1Very high31 Ų3142.4 Ų42.416%0.16225%0.245CC..Hα-helixtrans-64.1-42.2178-69.4170.6000111.9V98 P99 N106 I200 L203 A204V98-L102 HydrophobicContact CG1-CD1 3.92Å; V98-L102 HydrophobicContact CG1-CG 4.37Å; V98-L102 VanDerWaalsContact O-CG 3.29Å; V98-L102 WeakPolarHBondContact O-CG 3.06Å; V98-L102 PolarHBondContact O-N 3.41Å; P99-L102 PolarHBondContact O-N 3.42Å; L102-N106 WeakPolarHBondContact O-CB 3.11Å; L102-N106 PolarHBondContact O-N 3.15Å; L102-I200 HydrophobicContact CB-CG2 4.41Å; L102-I200 HydrophobicContact CD2-CG2 4.07Å; L102-L203 HydrophobicContact CD1-CD2 4.28Å; L102-L203 HydrophobicContact CD1-CG 4.07Å; L102-L203 HydrophobicContact CD2-CD2 4.25Å; L102-A204 HydrophobicContact CB-CB 3.7Å; L102-A204 HydrophobicContact CD1-CB 4.37Å
103Y90.9Very high90.1Very high52 Ų5240.2 Ų40.220%0.20423%0.234CC..Hα-helixtrans-66.2-42.7175.9-75-55.6000112P99 A100 N106 N107 A204 T208 R282P99-Y103 HydrophobicContact CB-CD2 4.47Å; P99-Y103 HydrophobicContact CB-CE2 4.35Å; P99-Y103 WeakPolarHBondContact O-CD2 3.33Å; P99-Y103 PolarHBondContact O-N 2.87Å; A100-Y103 PolarHBondContact O-N 2.83Å; Y103-N106 PolarHBondContact O-N 3.42Å; Y103-N107 PolarHBondContact O-N 3.3Å; Y103-N107 PolarHBondContact O-ND2 2.91Å; Y103-N107 PolarHBondContact O-OD1 3.41Å; Y103-A204 HydrophobicContact CD1-CB 3.87Å; Y103-A204 HydrophobicContact CE1-CB 3.65Å; Y103-A204 HydrophobicContact CE2-CB 4.42Å; Y103-A204 HydrophobicContact CG-CB 4.32Å; Y103-T208 VanDerWaalsContact CE2-OG1 3.3Å; Y103-T208 WeakPolarHBondContact CE2-OG1 3.37Å; Y103-T208 PolarHBondContact OH-OG1 3.47Å; Y103-R282 PolarHBondContact OH-NH1 3.5Å
104A87.8Confident89.9Confident8 Ų842.4 Ų42.47%0.06624%0.243CC..Hα-helixtrans-62.7-45.2176.300000111.8A100 A101 N106 N107 N108 I233A100-A104 WeakPolarHBondContact O-CB 3.43Å; A100-A104 PolarHBondContact O-N 3.38Å; A101-A104 PolarHBondContact O-N 2.88Å; A104-N106 PolarHBondContact O-N 3.44Å; A104-N107 PolarHBondContact O-N 2.72Å; A104-N108 PolarHBondContact O-N 3.34Å; A104-N108 VanDerWaalsContact O-N 3.08Å; A104-N108 PolarHBondContact O-ND2 3.04Å; A104-I233 HydrophobicContact CB-CB 4.37Å; A104-I233 HydrophobicContact CB-CG2 3.39Å
105F90Very high89.7Confident111 Ų11145.7 Ų45.749%0.48725%0.253SS..Hα-helixtrans-62.6-43.6175.9-171.6-94.9000111.5A101 N107 N108 L109 I200A101-F105 VanDerWaalsContact O-CB 3.3Å; A101-F105 WeakPolarHBondContact O-CB 3.32Å; A101-F105 PolarHBondContact O-N 3.01Å; F105-N107 VanDerWaalsContact C-N 3.32Å; F105-N107 PolarHBondContact O-N 3.02Å; F105-N108 PolarHBondContact O-N 3.45Å; F105-L109 HydrophobicContact CE1-CD2 4.27Å; F105-L109 WeakPolarHBondContact O-CB 3.45Å; F105-L109 PolarHBondContact O-N 3.37Å; F105-I200 HydrophobicContact CD1-CD1 3.34Å; F105-I200 HydrophobicContact CD1-CG2 4.28Å; F105-I200 HydrophobicContact CE1-CD1 3.25Å; F105-I200 HydrophobicContact CZ-CD1 4.49Å
106N92.5Very high89.4Confident8 Ų848.4 Ų48.44%0.04326%0.26CS..Hα-helixtrans-58.3-43.6176.8-167.1-109.7000112L102 Y103 A104 L109 V110 Y197 I200 S201L102-N106 WeakPolarHBondContact O-CB 3.11Å; L102-N106 PolarHBondContact O-N 3.15Å; Y103-N106 PolarHBondContact O-N 3.42Å; A104-N106 PolarHBondContact O-N 3.44Å; N106-L109 WeakPolarHBondContact O-CB 3.49Å; N106-L109 PolarHBondContact O-N 2.96Å; N106-V110 PolarHBondContact O-N 3.38Å; N106-Y197 WeakPolarHBondContact ND2-CD2 3.26Å; N106-Y197 VanDerWaalsContact ND2-CE2 3.25Å; N106-Y197 WeakPolarHBondContact ND2-CE2 3.45Å; N106-Y197 PolarHBondContact ND2-O 3.31Å; N106-Y197 WeakPolarHBondContact OD1-CE2 3.35Å; N106-I200 HydrophobicContact CB-CG2 4.08Å; N106-S201 PolarHBondContact ND2-N 3.44Å
107N87.4Confident89.2Confident83 Ų8348.3 Ų48.344%0.44426%0.26SS..Hα-helixtrans-64.3-44.3178-69.6-13.6000112.3Y103 A104 F105 L109 V110Y103-N107 PolarHBondContact O-N 3.3Å; Y103-N107 PolarHBondContact O-ND2 2.91Å; Y103-N107 PolarHBondContact O-OD1 3.41Å; A104-N107 PolarHBondContact O-N 2.72Å; F105-N107 VanDerWaalsContact C-N 3.32Å; F105-N107 PolarHBondContact O-N 3.02Å; N107-L109 VanDerWaalsContact C-N 3.29Å; N107-L109 PolarHBondContact O-N 3.2Å; N107-V110 WeakPolarHBondContact O-CB 3.47Å; N107-V110 PolarHBondContact O-N 3.23Å
108N86.3Confident88.8Confident89 Ų8947.9 Ų47.948%0.47625%0.253SS..Hα-helixtrans-64.5-36.1176.7-78.2-77.7000111.9A104 F105 V110 V111 L112A104-N108 PolarHBondContact O-N 3.34Å; A104-N108 VanDerWaalsContact O-N 3.08Å; A104-N108 PolarHBondContact O-ND2 3.04Å; F105-N108 PolarHBondContact O-N 3.45Å; N108-V110 VanDerWaalsContact C-N 3.29Å; N108-V110 PolarHBondContact O-N 3.04Å; N108-V111 PolarHBondContact O-N 3.25Å; N108-V111 VanDerWaalsContact O-N 3.16Å; N108-L112 PolarHBondContact O-N 2.97Å
109L88.7Confident88.1Confident10 Ų1049.1 Ų49.15%0.05226%0.263CS..Hα-helixtrans-63.2-36.3177.9-164.861.3000111.8F105 N106 N107 V111 L112 M113 L193 V196 Y197F105-L109 HydrophobicContact CE1-CD2 4.27Å; F105-L109 WeakPolarHBondContact O-CB 3.45Å; F105-L109 PolarHBondContact O-N 3.37Å; N106-L109 WeakPolarHBondContact O-CB 3.49Å; N106-L109 PolarHBondContact O-N 2.96Å; N107-L109 VanDerWaalsContact C-N 3.29Å; N107-L109 PolarHBondContact O-N 3.2Å; L109-V111 VanDerWaalsContact C-N 3.31Å; L109-V111 PolarHBondContact O-N 2.95Å; L109-L112 HydrophobicContact CD1-CD2 4.21Å; L109-L112 PolarHBondContact O-N 2.94Å; L109-M113 HydrophobicContact CG-CG 4.42Å; L109-M113 HydrophobicContact CG-SD 4.11Å; L109-M113 WeakPolarHBondContact O-CB 3.32Å; L109-M113 WeakPolarHBondContact O-CG 3.49Å; L109-M113 PolarHBondContact O-N 3.32Å; L109-L193 HydrophobicContact CD1-CD2 3.8Å; L109-V196 HydrophobicContact CD2-CB 4.36Å; L109-V196 HydrophobicContact CD2-CG1 3.94Å; L109-Y197 HydrophobicContact CB-CD2 4.45Å; L109-Y197 VanDerWaalsContact CD2-CA 3.46Å; L109-Y197 HydrophobicContact CD2-CD2 4.45Å
110V88Confident87.6Confident35 Ų3550.8 Ų50.821%0.21227%0.274CS..Hα-helixtrans-57.4-45.7173.4178.30000111.1N106 N107 N108 M113 Q114 F122 Y197N106-V110 PolarHBondContact O-N 3.38Å; N107-V110 WeakPolarHBondContact O-CB 3.47Å; N107-V110 PolarHBondContact O-N 3.23Å; N108-V110 VanDerWaalsContact C-N 3.29Å; N108-V110 PolarHBondContact O-N 3.04Å; V110-M113 PolarHBondContact O-N 2.8Å; V110-Q114 WeakPolarHBondContact O-CG 3.25Å; V110-Q114 PolarHBondContact O-N 3.48Å; V110-F122 HydrophobicContact CB-CZ 4.38Å; V110-F122 HydrophobicContact CG1-CE1 3.93Å; V110-F122 HydrophobicContact CG1-CZ 3.8Å; V110-F122 HydrophobicContact CG2-CE2 4.46Å; V110-F122 HydrophobicContact CG2-CZ 3.89Å; V110-Y197 HydrophobicContact CG2-CD2 3.84Å; V110-Y197 HydrophobicContact CG2-CE2 3.2Å
111V84.7Confident87.4Confident104 Ų10450.4 Ų50.463%0.6327%0.271SS*.Hα-helixtrans-65.6-47.6-179.9179.70000110.5N108 L109 M113 Q114N108-V111 PolarHBondContact O-N 3.25Å; N108-V111 VanDerWaalsContact O-N 3.16Å; L109-V111 VanDerWaalsContact C-N 3.31Å; L109-V111 PolarHBondContact O-N 2.95Å; V111-M113 VanDerWaalsContact C-N 3.26Å; V111-M113 PolarHBondContact O-N 2.88Å; V111-Q114 PolarHBondContact O-N 3.4Å
112L86.6Confident87.2Confident74 Ų7449.5 Ų49.539%0.38726%0.258SS..Hα-helixtrans-58.9-39.2177.6-178.369.3000111.8N108 L109 Q114 I115 Y116 L193N108-L112 PolarHBondContact O-N 2.97Å; L109-L112 HydrophobicContact CD1-CD2 4.21Å; L109-L112 PolarHBondContact O-N 2.94Å; L112-Q114 VanDerWaalsContact C-N 3.27Å; L112-Q114 PolarHBondContact O-N 2.99Å; L112-I115 HydrophobicContact CD1-CD1 4Å; L112-I115 WeakPolarHBondContact O-CB 3.36Å; L112-I115 WeakPolarHBondContact O-CG1 3.33Å; L112-I115 PolarHBondContact O-N 3.5Å; L112-I115 VanDerWaalsContact O-N 3.15Å; L112-Y116 HydrophobicContact CD1-CE2 4.21Å; L112-Y116 HydrophobicContact CG-CE2 4.3Å; L112-L193 HydrophobicContact CD2-CD2 4.34Å
113M87.5Confident86.8Confident0 Ų051.4 Ų51.40%027%0.266CS..Hα-helixtrans-64.2-29.8-179.4-76.5170.465.800113.5L109 V110 V111 I115 Y116 M117 F122 L193 V194 Y197L109-M113 HydrophobicContact CG-CG 4.42Å; L109-M113 HydrophobicContact CG-SD 4.11Å; L109-M113 WeakPolarHBondContact O-CB 3.32Å; L109-M113 WeakPolarHBondContact O-CG 3.49Å; L109-M113 PolarHBondContact O-N 3.32Å; V110-M113 PolarHBondContact O-N 2.8Å; V111-M113 VanDerWaalsContact C-N 3.26Å; V111-M113 PolarHBondContact O-N 2.88Å; M113-I115 PolarHBondContact O-N 3.49Å; M113-I115 VanDerWaalsContact O-N 3.11Å; M113-Y116 PolarHBondContact O-N 3.48Å; M113-M117 PolarHBondContact O-N 3.1Å; M113-F122 HydrophobicContact CE-CD2 3.43Å; M113-F122 VanDerWaalsContact CE-CD2 3.43Å; M113-F122 HydrophobicContact CE-CE2 3.72Å; M113-F122 HydrophobicContact SD-CD2 4.39Å; M113-F122 HydrophobicContact SD-CE2 4.17Å; M113-L193 HydrophobicContact CG-CB 3.63Å; M113-L193 HydrophobicContact CG-CD1 4.3Å; M113-L193 HydrophobicContact SD-CB 4.27Å; M113-V194 HydrophobicContact CE-CB 3.32Å; M113-V194 HydrophobicContact CE-CG2 3.67Å; M113-Y197 HydrophobicContact SD-CD2 4.45Å; M113-Y197 HydrophobicContact SD-CG 4.06Å
114Q83Confident86.6Confident64 Ų6449.6 Ų49.630%0.29926%0.261SS..Hα-helixtrans-63.1-16.4177.1-59.6-54.6-51.100112.8V110 V111 L112 M117V110-Q114 WeakPolarHBondContact O-CG 3.25Å; V110-Q114 PolarHBondContact O-N 3.48Å; V111-Q114 PolarHBondContact O-N 3.4Å; L112-Q114 VanDerWaalsContact C-N 3.27Å; L112-Q114 PolarHBondContact O-N 2.99Å; Q114-M117 CarbonylContact C-O 3.59Å; Q114-M117 WeakPolarHBondContact CA-O 3.44Å
115I86.8Confident86.8Confident111 Ų11150.9 Ų50.957%0.56927%0.266SS*.Hα-helixtrans-73.9-36.8173.5-55174.2000110.7L112 M113L112-I115 HydrophobicContact CD1-CD1 4Å; L112-I115 WeakPolarHBondContact O-CB 3.36Å; L112-I115 WeakPolarHBondContact O-CG1 3.33Å; L112-I115 PolarHBondContact O-N 3.5Å; L112-I115 VanDerWaalsContact O-N 3.15Å; M113-I115 PolarHBondContact O-N 3.49Å; M113-I115 VanDerWaalsContact O-N 3.11Å
116Y87.9Confident86.9Confident89 Ų8946.1 Ų46.135%0.34925%0.246SC..Hα-helixtrans-104.6-9-172.1-59.6-76.9000114.3L112 M113 T187 W189 L193L112-Y116 HydrophobicContact CD1-CE2 4.21Å; L112-Y116 HydrophobicContact CG-CE2 4.3Å; M113-Y116 PolarHBondContact O-N 3.48Å; Y116-T187 PolarHBondContact O-N 3.22Å; Y116-T187 PolarHBondContact O-OG1 3.28Å; Y116-W189 HydrophobicContact CD1-CB 4.28Å; Y116-L193 HydrophobicContact CD2-CD1 3.49Å; Y116-L193 VanDerWaalsContact CD2-CD1 3.49Å; Y116-L193 HydrophobicContact CE2-CD1 3.95Å; Y116-L193 HydrophobicContact CG-CD1 4.2Å
117M87.4Confident86.9Confident0 Ų046.2 Ų46.20%025%0.247CC..BIsolated β-bridgetrans-148.7142-174.1-177178.8-74.500110.3M113 Q114 S121 F122 L125 R185 I186 V194M113-M117 PolarHBondContact O-N 3.1Å; Q114-M117 CarbonylContact C-O 3.59Å; Q114-M117 WeakPolarHBondContact CA-O 3.44Å; M117-S121 VanDerWaalsContact CG-CB 3.47Å; M117-F122 HydrophobicContact CG-CB 4.4Å; M117-F122 WeakPolarHBondContact SD-CA 3.23Å; M117-F122 HydrophobicContact SD-CB 3.87Å; M117-F122 PolarHBondContact SD-N 2.9Å; M117-F122 VanDerWaalsContact SD-N 3.36Å; M117-L125 HydrophobicContact CE-CD1 3.44Å; M117-L125 VanDerWaalsContact CE-CD1 3.44Å; M117-L125 HydrophobicContact SD-CD1 4.04Å; M117-R185 WeakPolarHBondContact CA-O 3.18Å; M117-I186 HydrophobicContact CE-CG1 4.17Å; M117-I186 HydrophobicContact CE-CG2 3.78Å; M117-I186 HydrophobicContact CG-CG1 4.41Å; M117-V194 HydrophobicContact CE-CB 4.44Å; M117-V194 HydrophobicContact CE-CG1 4.29Å
118D84.3Confident87.2Confident20 Ų2044.8 Ų44.811%0.10724%0.239CC..  trans-72.4154.4172.460.7-79.3000112.6S120 S121 F122 R185D118-S120 VanDerWaalsContact C-N 3.25Å; D118-S120 PolarHBondContact O-N 3.36Å; D118-S120 VanDerWaalsContact OD2-CB 3.32Å; D118-S120 WeakPolarHBondContact OD2-CB 3.22Å; D118-S120 PolarHBondContact OD2-N 3Å; D118-S120 PolarHBondContact OD2-OG 2.82Å; D118-S121 PolarHBondContact O-N 3.26Å; D118-S121 VanDerWaalsContact OD1-CB 3.28Å; D118-S121 WeakPolarHBondContact OD1-CB 3.18Å; D118-S121 PolarHBondContact OD1-OG 2.99Å; D118-S121 WeakPolarHBondContact OD2-CB 3.5Å; D118-S121 PolarHBondContact OD2-N 2.84Å; D118-S121 PolarHBondContact OD2-OG 3.36Å; D118-F122 PolarHBondContact O-N 3Å; D118-R185 PolarHBondContact N-O 3.36Å; D118-R185 WeakPolarHBondContact OD1-CA 3.41Å; D118-R185 PolarHBondContact OD1-N 3.32Å
119P80.7Confident87.5Confident85 Ų8542.3 Ų42.355%0.55222%0.224SC*.Hα-helixtrans-56.2-36.5-178.7-24.630.9000114.1F122 Q123P119-F122 PolarHBondContact O-N 3.41Å; P119-Q123 WeakPolarHBondContact O-CB 3.49Å; P119-Q123 PolarHBondContact O-N 2.82Å
120S82.1Confident87.8Confident36 Ų3642 Ų4225%0.25222%0.223SC..Hα-helixtrans-63.4-52.317919.90000112.5D118 F122 Q123 V124 L168D118-S120 VanDerWaalsContact C-N 3.25Å; D118-S120 PolarHBondContact O-N 3.36Å; D118-S120 VanDerWaalsContact OD2-CB 3.32Å; D118-S120 WeakPolarHBondContact OD2-CB 3.22Å; D118-S120 PolarHBondContact OD2-N 3Å; D118-S120 PolarHBondContact OD2-OG 2.82Å; S120-F122 VanDerWaalsContact C-N 3.28Å; S120-F122 PolarHBondContact O-N 3.15Å; S120-Q123 PolarHBondContact O-N 3.43Å; S120-V124 PolarHBondContact O-N 3.38Å; S120-V124 VanDerWaalsContact O-N 3.13Å; S120-L168 VanDerWaalsContact CB-CD2 3.47Å
121S86.1Confident88Confident0 Ų042.1 Ų42.10%023%0.227CC..Hα-helixtrans-57.8-42.9174.1-66.80000111.3M117 D118 Q123 V124 L125 L184 I186M117-S121 VanDerWaalsContact CG-CB 3.47Å; D118-S121 PolarHBondContact O-N 3.26Å; D118-S121 VanDerWaalsContact OD1-CB 3.28Å; D118-S121 WeakPolarHBondContact OD1-CB 3.18Å; D118-S121 PolarHBondContact OD1-OG 2.99Å; D118-S121 WeakPolarHBondContact OD2-CB 3.5Å; D118-S121 PolarHBondContact OD2-N 2.84Å; D118-S121 PolarHBondContact OD2-OG 3.36Å; S121-Q123 PolarHBondContact O-N 3.1Å; S121-V124 PolarHBondContact O-N 3.31Å; S121-L125 WeakPolarHBondContact O-CB 3.4Å; S121-L125 WeakPolarHBondContact O-CG 3.47Å; S121-L125 PolarHBondContact O-N 3.34Å; S121-L184 WeakPolarHBondContact OG-CB 3.23Å; S121-L184 WeakPolarHBondContact OG-CD2 3.42Å; S121-I186 WeakPolarHBondContact OG-CG1 3.48Å
122F87.8Confident88.5Confident29 Ų2938 Ų3813%0.12720%0.203CC..Hα-helixtrans-60.6-46.7176.8169.3-107.6000111.4V110 M113 M117 D118 P119 S120 V124 L125 S126 Y197V110-F122 HydrophobicContact CB-CZ 4.38Å; V110-F122 HydrophobicContact CG1-CE1 3.93Å; V110-F122 HydrophobicContact CG1-CZ 3.8Å; V110-F122 HydrophobicContact CG2-CE2 4.46Å; V110-F122 HydrophobicContact CG2-CZ 3.89Å; M113-F122 HydrophobicContact CE-CD2 3.43Å; M113-F122 VanDerWaalsContact CE-CD2 3.43Å; M113-F122 HydrophobicContact CE-CE2 3.72Å; M113-F122 HydrophobicContact SD-CD2 4.39Å; M113-F122 HydrophobicContact SD-CE2 4.17Å; M117-F122 HydrophobicContact CG-CB 4.4Å; M117-F122 WeakPolarHBondContact SD-CA 3.23Å; M117-F122 HydrophobicContact SD-CB 3.87Å; M117-F122 PolarHBondContact SD-N 2.9Å; M117-F122 VanDerWaalsContact SD-N 3.36Å; D118-F122 PolarHBondContact O-N 3Å; P119-F122 PolarHBondContact O-N 3.41Å; S120-F122 VanDerWaalsContact C-N 3.28Å; S120-F122 PolarHBondContact O-N 3.15Å; F122-V124 PolarHBondContact O-N 3.43Å; F122-L125 PolarHBondContact O-N 3.26Å; F122-S126 WeakPolarHBondContact O-CB 3.44Å; F122-S126 PolarHBondContact O-N 2.78Å; F122-S126 PolarHBondContact O-OG 3.4Å; F122-Y197 HydrophobicContact CE2-CD1 4.1Å; F122-Y197 AromaticContact CE2-CE1 3.97Å; F122-Y197 HydrophobicContact CE2-CE1 3.97Å; F122-Y197 HydrophobicContact CZ-CE1 4.06Å
123Q85.7Confident88.8Confident72 Ų7234.7 Ų34.734%0.33619%0.186SC..Hα-helixtrans-60.9-46.3-177.1-164173.8-9.800111.1P119 S120 S121 S126 N127 S167P119-Q123 WeakPolarHBondContact O-CB 3.49Å; P119-Q123 PolarHBondContact O-N 2.82Å; S120-Q123 PolarHBondContact O-N 3.43Å; S121-Q123 PolarHBondContact O-N 3.1Å; Q123-S126 PolarHBondContact O-OG 2.9Å; Q123-N127 PolarHBondContact O-ND2 3.48Å; Q123-S167 PolarHBondContact NE2-OG 3Å
124V88.3Confident89.1Confident14 Ų1434.7 Ų34.79%0.08519%0.186CC..Hα-helixtrans-60-54.8175.7171.70000111.1S120 S121 F122 S126 N127 V161 Y165S120-V124 PolarHBondContact O-N 3.38Å; S120-V124 VanDerWaalsContact O-N 3.13Å; S121-V124 PolarHBondContact O-N 3.31Å; F122-V124 PolarHBondContact O-N 3.43Å; V124-S126 VanDerWaalsContact C-N 3.33Å; V124-S126 PolarHBondContact O-N 3.26Å; V124-N127 WeakPolarHBondContact O-CB 3.41Å; V124-N127 PolarHBondContact O-N 3.5Å; V124-N127 PolarHBondContact O-ND2 2.87Å; V124-V161 HydrophobicContact CG1-CG1 4.1Å; V124-Y165 HydrophobicContact CB-CE2 4.43Å; V124-Y165 HydrophobicContact CG1-CD2 4.44Å; V124-Y165 HydrophobicContact CG1-CE2 3.7Å; V124-Y165 HydrophobicContact CG2-CD2 3.92Å; V124-Y165 HydrophobicContact CG2-CE2 3.78Å; V124-Y165 HydrophobicContact CG2-CG 4.36Å
125L91.4Very high89.7Confident35 Ų3536.5 Ų36.518%0.18320%0.197CC..Hα-helixtrans-70.8-26.7-174.5-68171.6000113.2M117 S121 F122 N127 L128 I186 L191 V194M117-L125 HydrophobicContact CE-CD1 3.44Å; M117-L125 VanDerWaalsContact CE-CD1 3.44Å; M117-L125 HydrophobicContact SD-CD1 4.04Å; S121-L125 WeakPolarHBondContact O-CB 3.4Å; S121-L125 WeakPolarHBondContact O-CG 3.47Å; S121-L125 PolarHBondContact O-N 3.34Å; F122-L125 PolarHBondContact O-N 3.26Å; L125-N127 PolarHBondContact O-N 3.38Å; L125-N127 VanDerWaalsContact O-N 3.15Å; L125-L128 WeakPolarHBondContact O-CB 3.17Å; L125-L128 VanDerWaalsContact O-CD1 3.32Å; L125-L128 WeakPolarHBondContact O-CD1 3.29Å; L125-L128 PolarHBondContact O-N 2.97Å; L125-L128 VanDerWaalsContact O-N 3.1Å; L125-I186 HydrophobicContact CD1-CD1 4.01Å; L125-L191 HydrophobicContact CD1-CD1 4.48Å; L125-V194 HydrophobicContact CB-CG1 4.14Å; L125-V194 HydrophobicContact CB-CG2 3.79Å; L125-V194 HydrophobicContact CD1-CG1 4.2Å
126S91.1Very high90Very high10 Ų1031.9 Ų31.97%0.0717%0.173CC..Hα-helixtrans-63.9-19.7178750000113F122 Q123 V124 L128 K129F122-S126 WeakPolarHBondContact O-CB 3.44Å; F122-S126 PolarHBondContact O-N 2.78Å; F122-S126 PolarHBondContact O-OG 3.4Å; Q123-S126 PolarHBondContact O-OG 2.9Å; V124-S126 VanDerWaalsContact C-N 3.33Å; V124-S126 PolarHBondContact O-N 3.26Å; S126-L128 PolarHBondContact O-N 3.46Å; S126-K129 VanDerWaalsContact O-CB 3.25Å; S126-K129 WeakPolarHBondContact O-CB 3.44Å; S126-K129 WeakPolarHBondContact O-CD 3.35Å; S126-K129 WeakPolarHBondContact O-CG 3.1Å; S126-K129 PolarHBondContact O-N 3.48Å
127N93.1Very high90.3Very high10 Ų1028.8 Ų28.85%0.05316%0.161CC..THydrogen-bonded Turntrans-64.1-19.6175.2-69.1-68.8000112.7Q123 V124 L125 K129 I130 M157 G160 V161 S164Q123-N127 PolarHBondContact O-ND2 3.48Å; V124-N127 WeakPolarHBondContact O-CB 3.41Å; V124-N127 PolarHBondContact O-N 3.5Å; V124-N127 PolarHBondContact O-ND2 2.87Å; L125-N127 PolarHBondContact O-N 3.38Å; L125-N127 VanDerWaalsContact O-N 3.15Å; N127-K129 PolarHBondContact O-N 2.96Å; N127-I130 WeakPolarHBondContact O-CB 3.23Å; N127-I130 PolarHBondContact O-N 3.46Å; N127-M157 HydrophobicContact CB-CG 4.36Å; N127-G160 VanDerWaalsContact CG-C 3.48Å; N127-G160 VanDerWaalsContact ND2-C 3.34Å; N127-G160 PolarHBondContact ND2-O 3.08Å; N127-G160 WeakPolarHBondContact OD1-CA 3.49Å; N127-V161 HydrophobicContact CB-CG2 3.89Å; N127-S164 PolarHBondContact ND2-OG 3.42Å; N127-S164 VanDerWaalsContact ND2-OG 3.14Å
128L92.9Very high90.5Very high54 Ų5430.6 Ų30.628%0.28317%0.174SC..Hα-helixtrans-58.2-19.1171-86.270.2000112.4L125 S126 I130 A131 S132 M157 L195 C198L125-L128 WeakPolarHBondContact O-CB 3.17Å; L125-L128 VanDerWaalsContact O-CD1 3.32Å; L125-L128 WeakPolarHBondContact O-CD1 3.29Å; L125-L128 PolarHBondContact O-N 2.97Å; L125-L128 VanDerWaalsContact O-N 3.1Å; S126-L128 PolarHBondContact O-N 3.46Å; L128-I130 PolarHBondContact O-N 3.32Å; L128-I130 VanDerWaalsContact O-N 3.17Å; L128-A131 PolarHBondContact O-N 2.92Å; L128-A131 VanDerWaalsContact O-N 3.13Å; L128-S132 PolarHBondContact O-N 3.29Å; L128-M157 HydrophobicContact CD1-CE 4Å; L128-M157 HydrophobicContact CG-CE 4.33Å; L128-L195 HydrophobicContact CD2-CD2 3.96Å; L128-C198 HydrophobicContact CB-CB 4.4Å
129K93.4Very high90.8Very high37 Ų3733.7 Ų33.716%0.16120%0.197CC..Hα-helixtrans-56.1-28.7171.678.7-168.9176-168.30112.7S126 N127 T133 C198S126-K129 VanDerWaalsContact O-CB 3.25Å; S126-K129 WeakPolarHBondContact O-CB 3.44Å; S126-K129 WeakPolarHBondContact O-CD 3.35Å; S126-K129 WeakPolarHBondContact O-CG 3.1Å; S126-K129 PolarHBondContact O-N 3.48Å; N127-K129 PolarHBondContact O-N 2.96Å; K129-T133 VanDerWaalsContact O-CB 3.26Å; K129-T133 WeakPolarHBondContact O-CB 2.97Å; K129-T133 PolarHBondContact O-N 3.27Å; K129-T133 PolarHBondContact O-OG1 3.42Å; K129-C198 HydrophobicContact CB-CB 4.31Å; K129-C198 PolarHBondContact N-SG 2.98Å; K129-C198 VanDerWaalsContact N-SG 3.43Å
130I93.9Very high91.2Very high4 Ų431.9 Ų31.92%0.02119%0.186CC..Hα-helixtrans-64.3-51.3176.6-67.3165.6000109.5N127 L128 T133 A134 L156 M157 L283N127-I130 WeakPolarHBondContact O-CB 3.23Å; N127-I130 PolarHBondContact O-N 3.46Å; L128-I130 PolarHBondContact O-N 3.32Å; L128-I130 VanDerWaalsContact O-N 3.17Å; I130-T133 PolarHBondContact O-N 3Å; I130-A134 WeakPolarHBondContact O-CB 3.33Å; I130-A134 PolarHBondContact O-N 3.16Å; I130-L156 HydrophobicContact CD1-CG 4.47Å; I130-M157 HydrophobicContact CB-CB 4.27Å; I130-M157 HydrophobicContact CD1-CB 4.3Å; I130-M157 HydrophobicContact CG2-CB 4.21Å; I130-L283 HydrophobicContact CG1-CD2 4.29Å; I130-L283 HydrophobicContact CG2-CD1 4.22Å
131A94.3Very high91.5Very high37 Ų3732 Ų3231%0.30618%0.184SC..Hα-helixtrans-62.5-44.5177.200000111.6L128 T133 A134 L135 M157L128-A131 PolarHBondContact O-N 2.92Å; L128-A131 VanDerWaalsContact O-N 3.13Å; A131-T133 PolarHBondContact O-N 2.63Å; A131-A134 WeakPolarHBondContact O-CB 3.3Å; A131-A134 PolarHBondContact O-N 2.99Å; A131-L135 WeakPolarHBondContact O-CG 3.46Å; A131-L135 PolarHBondContact O-N 3.02Å; A131-M157 HydrophobicContact CB-SD 4.05Å
132S94.5Very high91.4Very high17 Ų1734.9 Ų34.912%0.11921%0.213CC..Hα-helixtrans-60.5-45.7177.6-175.60000112.3L128 A134 L135 L136 C198 F199L128-S132 PolarHBondContact O-N 3.29Å; S132-A134 VanDerWaalsContact C-N 3.32Å; S132-A134 PolarHBondContact O-N 3.47Å; S132-L135 PolarHBondContact O-N 3.44Å; S132-L136 WeakPolarHBondContact O-CB 3.49Å; S132-L136 WeakPolarHBondContact O-CG 3.29Å; S132-L136 PolarHBondContact O-N 3.31Å; S132-C198 PolarHBondContact OG-O 3.02Å; S132-F199 WeakPolarHBondContact OG-CA 3.49Å
133T93.5Very high91.3Very high4 Ų438.6 Ų38.63%0.02523%0.229CC..Hα-helixtrans-62.8-40.4176.9-55.70000111.1K129 I130 A131 Y137 G202 A205 V206 L283K129-T133 VanDerWaalsContact O-CB 3.26Å; K129-T133 WeakPolarHBondContact O-CB 2.97Å; K129-T133 PolarHBondContact O-N 3.27Å; K129-T133 PolarHBondContact O-OG1 3.42Å; I130-T133 PolarHBondContact O-N 3Å; A131-T133 PolarHBondContact O-N 2.63Å; T133-Y137 WeakPolarHBondContact O-CB 3.37Å; T133-Y137 PolarHBondContact O-N 2.73Å; T133-G202 WeakPolarHBondContact OG1-CA 3.36Å; T133-A205 HydrophobicContact CG2-CB 4.44Å; T133-V206 HydrophobicContact CG2-CG2 4.36Å; T133-L283 HydrophobicContact CG2-CD1 3.96Å; T133-L283 HydrophobicContact CG2-CG 4.46Å
134A93.8Very high91.4Very high0 Ų046.5 Ų46.50%026%0.255CS..Hα-helixtrans-63.7-45177.500000112.5I130 A131 S132 Y137 S138 L145 W150 L153I130-A134 WeakPolarHBondContact O-CB 3.33Å; I130-A134 PolarHBondContact O-N 3.16Å; A131-A134 WeakPolarHBondContact O-CB 3.3Å; A131-A134 PolarHBondContact O-N 2.99Å; S132-A134 VanDerWaalsContact C-N 3.32Å; S132-A134 PolarHBondContact O-N 3.47Å; A134-Y137 PolarHBondContact O-N 2.91Å; A134-S138 PolarHBondContact O-N 3.4Å; A134-L145 HydrophobicContact CB-CD1 4.42Å; A134-W150 HydrophobicContact CB-CH2 4.31Å; A134-W150 HydrophobicContact CB-CZ3 4.07Å; A134-L153 HydrophobicContact CB-CD1 3.62Å
135L94.3Very high91.4Very high102 Ų10246.8 Ų46.853%0.53426%0.256SS..Hα-helixtrans-61.9-48.7176.7-73.5165.5000111.3A131 S132 Y137 S138 S139 W150A131-L135 WeakPolarHBondContact O-CG 3.46Å; A131-L135 PolarHBondContact O-N 3.02Å; S132-L135 PolarHBondContact O-N 3.44Å; L135-Y137 VanDerWaalsContact C-N 3.35Å; L135-S138 PolarHBondContact O-N 3.25Å; L135-S139 PolarHBondContact O-N 3.31Å; L135-S139 PolarHBondContact O-OG 3.05Å; L135-S139 VanDerWaalsContact O-OG 3.09Å; L135-W150 HydrophobicContact CD2-CH2 3.59Å; L135-W150 HydrophobicContact CD2-CZ2 4.49Å; L135-W150 HydrophobicContact CD2-CZ3 4.21Å; L135-W150 HydrophobicContact CG-CH2 3.98Å; L135-W150 HydrophobicContact CG-CZ3 4.37Å
136L94.1Very high91.5Very high15 Ų1553.5 Ų53.58%0.07928%0.279CS..Hα-helixtrans-67.3-34.8178-70.7170000112.3S132 S138 S139 C140 F199 L203 V206S132-L136 WeakPolarHBondContact O-CB 3.49Å; S132-L136 WeakPolarHBondContact O-CG 3.29Å; S132-L136 PolarHBondContact O-N 3.31Å; L136-S138 VanDerWaalsContact C-N 3.3Å; L136-S138 PolarHBondContact O-N 3.09Å; L136-S139 PolarHBondContact O-N 2.74Å; L136-C140 WeakPolarHBondContact O-CA 3.35Å; L136-C140 WeakPolarHBondContact O-CB 3.24Å; L136-C140 PolarHBondContact O-N 3.23Å; L136-F199 HydrophobicContact CD1-CD2 4.2Å; L136-F199 HydrophobicContact CD1-CE2 4.19Å; L136-F199 HydrophobicContact CD2-CE2 3.91Å; L136-F199 HydrophobicContact CD2-CZ 4.42Å; L136-F199 HydrophobicContact CG-CE2 4.47Å; L136-L203 HydrophobicContact CD1-CB 4.06Å; L136-L203 VanDerWaalsContact CD1-N 3.29Å; L136-V206 HydrophobicContact CB-CB 4.43Å; L136-V206 HydrophobicContact CB-CG2 3.91Å
137Y93Very high91.6Very high24 Ų2458 Ų589%0.09431%0.311CS..Hα-helixtrans-62.4-41172.4178.4-92.9000110.7T133 A134 L135 L141 K143 L145 I280T133-Y137 WeakPolarHBondContact O-CB 3.37Å; T133-Y137 PolarHBondContact O-N 2.73Å; A134-Y137 PolarHBondContact O-N 2.91Å; L135-Y137 VanDerWaalsContact C-N 3.35Å; Y137-L141 HydrophobicContact CD2-CD1 3.47Å; Y137-L141 VanDerWaalsContact CD2-CD1 3.47Å; Y137-L141 HydrophobicContact CE2-CD1 3.82Å; Y137-L141 HydrophobicContact CG-CD1 4.33Å; Y137-L141 WeakPolarHBondContact O-CB 3.32Å; Y137-K143 HydrophobicContact CD1-CB 3.94Å; Y137-K143 HydrophobicContact CE1-CB 3.39Å; Y137-K143 HydrophobicContact CE1-CG 3.87Å; Y137-K143 HydrophobicContact CE2-CG 4.32Å; Y137-L145 HydrophobicContact CD1-CD1 4.48Å; Y137-L145 HydrophobicContact CD1-CD2 4.27Å; Y137-L145 HydrophobicContact CD1-CG 4.44Å; Y137-L145 HydrophobicContact CE1-CD2 4.09Å; Y137-I280 HydrophobicContact CD1-CD1 3.5Å; Y137-I280 VanDerWaalsContact CD1-CD1 3.5Å; Y137-I280 HydrophobicContact CD1-CG1 4.3Å; Y137-I280 HydrophobicContact CD2-CD1 4.44Å; Y137-I280 HydrophobicContact CD2-CG1 4.48Å; Y137-I280 HydrophobicContact CE1-CD1 3.52Å; Y137-I280 HydrophobicContact CE1-CG1 4.48Å; Y137-I280 HydrophobicContact CE2-CD1 4.49Å; Y137-I280 HydrophobicContact CG-CD1 3.98Å; Y137-I280 HydrophobicContact CG-CG1 4.29Å
138S91.4Very high91.6Very high38 Ų3859.7 Ų59.727%0.26633%0.326SS..Hα-helixtrans-70.2-43.8177-169.90000112.7A134 L135 L136 G142 K143A134-S138 PolarHBondContact O-N 3.4Å; L135-S138 PolarHBondContact O-N 3.25Å; L136-S138 VanDerWaalsContact C-N 3.3Å; L136-S138 PolarHBondContact O-N 3.09Å; S138-G142 WeakPolarHBondContact O-CA 3.23Å; S138-G142 PolarHBondContact O-N 3.39Å; S138-K143 VanDerWaalsContact CA-O 3.26Å; S138-K143 WeakPolarHBondContact CA-O 3.32Å; S138-K143 PolarHBondContact O-N 3.11Å; S138-K143 PolarHBondContact OG-O 3.48Å
139S90.5Very high91.6Very high85 Ų8558.8 Ų58.859%0.59432%0.32SS*.Hα-helixtrans-82.7-48.5-17464.10000113.4L135 L136L135-S139 PolarHBondContact O-N 3.31Å; L135-S139 PolarHBondContact O-OG 3.05Å; L135-S139 VanDerWaalsContact O-OG 3.09Å; L136-S139 PolarHBondContact O-N 2.74Å
140C89.9Confident91.7Very high46 Ų4661.6 Ų61.631%0.31133%0.33SS..Hα-helixtrans-83.2-30.9-173.1-580000114.1L136 V206 R210L136-C140 WeakPolarHBondContact O-CA 3.35Å; L136-C140 WeakPolarHBondContact O-CB 3.24Å; L136-C140 PolarHBondContact O-N 3.23Å; C140-V206 HydrophobicContact CB-CG1 3.79Å; C140-R210 PolarHBondContact O-NH1 2.66Å
141L87.6Confident91.8Very high40 Ų4066.2 Ų66.221%0.20936%0.355CS..SBendtrans-95.8-4.2174.6-71.3159.4000112.4Y137 K143 V206 E209 R210Y137-L141 HydrophobicContact CD2-CD1 3.47Å; Y137-L141 VanDerWaalsContact CD2-CD1 3.47Å; Y137-L141 HydrophobicContact CE2-CD1 3.82Å; Y137-L141 HydrophobicContact CG-CD1 4.33Å; Y137-L141 WeakPolarHBondContact O-CB 3.32Å; L141-K143 HydrophobicContact CB-CG 4.01Å; L141-K143 PolarHBondContact O-N 3.39Å; L141-V206 HydrophobicContact CD1-CG1 3.76Å; L141-V206 HydrophobicContact CG-CG1 3.84Å; L141-E209 HydrophobicContact CD1-CG 4.18Å; L141-R210 HydrophobicContact CD2-CB 3.89Å; L141-R210 HydrophobicContact CD2-CG 4.29Å
142G84Confident91.9Very high59 Ų5964.5 Ų64.561%0.60834%0.34SS*.  trans63.922.4179.200000114S138S138-G142 WeakPolarHBondContact O-CA 3.23Å; S138-G142 PolarHBondContact O-N 3.39Å
143K87.1Confident91.9Very high107 Ų10763.9 Ų63.947%0.46534%0.336SS..PPolyproline II helixtrans-87.7121.3-177.4-65.1-67-176.5-176.60109.9Y137 S138 L141 L145Y137-K143 HydrophobicContact CD1-CB 3.94Å; Y137-K143 HydrophobicContact CE1-CB 3.39Å; Y137-K143 HydrophobicContact CE1-CG 3.87Å; Y137-K143 HydrophobicContact CE2-CG 4.32Å; S138-K143 VanDerWaalsContact CA-O 3.26Å; S138-K143 WeakPolarHBondContact CA-O 3.32Å; S138-K143 PolarHBondContact O-N 3.11Å; S138-K143 PolarHBondContact OG-O 3.48Å; L141-K143 HydrophobicContact CB-CG 4.01Å; L141-K143 PolarHBondContact O-N 3.39Å; K143-L145 PolarHBondContact O-N 3.29Å
144R87.3Confident92.1Very high238 Ų23865.9 Ų65.990%0.89836%0.357SS*.PPolyproline II helixtrans-80.1120.3177-63-175.9-178.8-174.2-0.4110.3
145L89.2Confident92.2Very high20 Ų2067.2 Ų67.211%0.10536%0.364CS..PPolyproline II helixtrans-90.1134.1171.8-66.7172.7000110A134 Y137 K143 Q149 W150 L153 I280 Y323A134-L145 HydrophobicContact CB-CD1 4.42Å; Y137-L145 HydrophobicContact CD1-CD1 4.48Å; Y137-L145 HydrophobicContact CD1-CD2 4.27Å; Y137-L145 HydrophobicContact CD1-CG 4.44Å; Y137-L145 HydrophobicContact CE1-CD2 4.09Å; K143-L145 PolarHBondContact O-N 3.29Å; L145-Q149 HydrophobicContact CB-CB 4.4Å; L145-Q149 HydrophobicContact CD2-CB 4.26Å; L145-W150 HydrophobicContact CB-CG 4.48Å; L145-W150 HydrophobicContact CD1-CD2 4.45Å; L145-W150 HydrophobicContact CD1-CH2 4.39Å; L145-W150 HydrophobicContact CD1-CZ2 3.98Å; L145-L153 HydrophobicContact CD1-CD1 3.9Å; L145-I280 HydrophobicContact CD1-CD1 4.43Å; L145-I280 HydrophobicContact CD2-CD1 3.73Å; L145-Y323 HydrophobicContact CD2-CE2 4.32Å
146R92.6Very high92.3Very high176 Ų17662.4 Ų62.466%0.66434%0.338SS*.PPolyproline II helixtrans-72.7158.3174.1-63.4178.9177.6-179.5-2.6110.4A148 Q149 W150R146-A148 PolarHBondContact O-N 3.33Å; R146-Q149 HydrophobicContact CB-CG 4.33Å; R146-Q149 WeakPolarHBondContact O-CA 3.39Å; R146-Q149 WeakPolarHBondContact O-CB 3.44Å; R146-Q149 PolarHBondContact O-N 3.43Å; R146-W150 PolarHBondContact O-N 3.43Å
147S92.2Very high92.4Very high106 Ų10664.1 Ų64.174%0.74135%0.347SS*.Hα-helixtrans-56.7-37.3177.2-48.30000112.8Q149 W150 L151S147-Q149 VanDerWaalsContact C-N 3.32Å; S147-Q149 PolarHBondContact O-N 3Å; S147-W150 PolarHBondContact O-N 3.34Å; S147-L151 PolarHBondContact O-N 3.09Å
148A93.3Very high92.4Very high45 Ų4564 Ų6437%0.37235%0.353SS..Hα-helixtrans-62.6-36.7173.700000112.9R146 L151 A152R146-A148 PolarHBondContact O-N 3.33Å; A148-L151 PolarHBondContact O-N 3.16Å; A148-A152 WeakPolarHBondContact O-CB 3.19Å; A148-A152 PolarHBondContact O-N 3.41Å
149Q94Very high92.6Very high34 Ų3462.2 Ų62.216%0.15934%0.34CS..Hα-helixtrans-72.8-36.7177.1-66.8177-38.500111.6L145 R146 S147 A152 L153 Y323L145-Q149 HydrophobicContact CB-CB 4.4Å; L145-Q149 HydrophobicContact CD2-CB 4.26Å; R146-Q149 HydrophobicContact CB-CG 4.33Å; R146-Q149 WeakPolarHBondContact O-CA 3.39Å; R146-Q149 WeakPolarHBondContact O-CB 3.44Å; R146-Q149 PolarHBondContact O-N 3.43Å; S147-Q149 VanDerWaalsContact C-N 3.32Å; S147-Q149 PolarHBondContact O-N 3Å; Q149-A152 PolarHBondContact O-N 3.46Å; Q149-L153 VanDerWaalsContact O-CG 3.23Å; Q149-L153 WeakPolarHBondContact O-CG 3.43Å; Q149-L153 PolarHBondContact O-N 3.18Å; Q149-Y323 HydrophobicContact CB-CD2 3.75Å; Q149-Y323 HydrophobicContact CB-CE2 3.82Å; Q149-Y323 HydrophobicContact CG-CD2 3.75Å; Q149-Y323 HydrophobicContact CG-CE2 3.87Å; Q149-Y323 HydrophobicContact CG-CG 4.41Å
150W95.4Very high92.6Very high96 Ų9658.2 Ų58.236%0.36431%0.312SS..Hα-helixtrans-61.3-46.2170.8-82.6108.6000111.8A134 L135 L145 R146 S147 A152 L153 G154A134-W150 HydrophobicContact CB-CH2 4.31Å; A134-W150 HydrophobicContact CB-CZ3 4.07Å; L135-W150 HydrophobicContact CD2-CH2 3.59Å; L135-W150 HydrophobicContact CD2-CZ2 4.49Å; L135-W150 HydrophobicContact CD2-CZ3 4.21Å; L135-W150 HydrophobicContact CG-CH2 3.98Å; L135-W150 HydrophobicContact CG-CZ3 4.37Å; L145-W150 HydrophobicContact CB-CG 4.48Å; L145-W150 HydrophobicContact CD1-CD2 4.45Å; L145-W150 HydrophobicContact CD1-CH2 4.39Å; L145-W150 HydrophobicContact CD1-CZ2 3.98Å; R146-W150 PolarHBondContact O-N 3.43Å; S147-W150 PolarHBondContact O-N 3.34Å; W150-A152 VanDerWaalsContact C-N 3.35Å; W150-A152 PolarHBondContact O-N 2.93Å; W150-L153 PolarHBondContact O-N 2.93Å; W150-G154 PolarHBondContact O-N 3.46Å
151L95.7Very high92.6Very high102 Ų10257.5 Ų57.553%0.53431%0.306SS..Hα-helixtrans-60-45.8175.3179.962.2000111.2S147 A148 L153 G154 I155 L322S147-L151 PolarHBondContact O-N 3.09Å; A148-L151 PolarHBondContact O-N 3.16Å; L151-L153 VanDerWaalsContact C-N 3.33Å; L151-L153 PolarHBondContact O-N 2.61Å; L151-G154 PolarHBondContact O-N 3.38Å; L151-G154 VanDerWaalsContact O-N 3.16Å; L151-I155 HydrophobicContact CD1-CD1 4.24Å; L151-I155 HydrophobicContact CD1-CG1 4.39Å; L151-I155 HydrophobicContact CG-CD1 3.96Å; L151-I155 WeakPolarHBondContact O-CG1 3.48Å; L151-I155 PolarHBondContact O-N 3.45Å; L151-L322 HydrophobicContact CD2-CD1 4.32Å; L151-L322 HydrophobicContact CG-CD1 4.5Å
152A96.1Very high92.8Very high0 Ų057.6 Ų57.60%031%0.31CS..Hα-helixtrans-57.3-43.7176.600000112.6A148 Q149 W150 I155 L156 A319 L322 Y323A148-A152 WeakPolarHBondContact O-CB 3.19Å; A148-A152 PolarHBondContact O-N 3.41Å; Q149-A152 PolarHBondContact O-N 3.46Å; W150-A152 VanDerWaalsContact C-N 3.35Å; W150-A152 PolarHBondContact O-N 2.93Å; A152-I155 PolarHBondContact O-N 2.89Å; A152-L156 WeakPolarHBondContact O-CB 3.44Å; A152-L156 PolarHBondContact O-N 3.16Å; A152-A319 WeakPolarHBondContact CB-O 3.46Å; A152-A319 VanDerWaalsContact O-CB 3.28Å; A152-A319 WeakPolarHBondContact O-CB 3.32Å; A152-L322 HydrophobicContact CB-CB 3.91Å; A152-Y323 HydrophobicContact CB-CD2 4.4Å
153L95.7Very high92.9Very high5 Ų555.4 Ų55.43%0.02628%0.284CS..Hα-helixtrans-68.8-34.2177.7-66.2169.3000112.2A134 L145 Q149 W150 L151 L156 M157 I280A134-L153 HydrophobicContact CB-CD1 3.62Å; L145-L153 HydrophobicContact CD1-CD1 3.9Å; Q149-L153 VanDerWaalsContact O-CG 3.23Å; Q149-L153 WeakPolarHBondContact O-CG 3.43Å; Q149-L153 PolarHBondContact O-N 3.18Å; W150-L153 PolarHBondContact O-N 2.93Å; L151-L153 VanDerWaalsContact C-N 3.33Å; L151-L153 PolarHBondContact O-N 2.61Å; L153-L156 HydrophobicContact CD2-CD2 4.47Å; L153-L156 PolarHBondContact O-N 2.78Å; L153-M157 WeakPolarHBondContact O-CB 3.05Å; L153-M157 PolarHBondContact O-N 3.38Å; L153-I280 HydrophobicContact CD1-CD1 4.35Å; L153-I280 HydrophobicContact CD2-CG2 3.79Å
154G96.4Very high92.9Very high45 Ų4550.4 Ų50.446%0.46426%0.262SS..Hα-helixtrans-63.6-45.3171.300000112.4W150 L151 L156 M157 G158W150-G154 PolarHBondContact O-N 3.46Å; L151-G154 PolarHBondContact O-N 3.38Å; L151-G154 VanDerWaalsContact O-N 3.16Å; G154-L156 VanDerWaalsContact C-N 3.33Å; G154-L156 PolarHBondContact O-N 3.01Å; G154-M157 PolarHBondContact O-N 3.29Å; G154-G158 PolarHBondContact O-N 2.91Å
155I96.6Very high92.6Very high29 Ų2944.8 Ų44.815%0.14924%0.242CC..Hα-helixtrans-62.6-41.6174.4-65.5165.9000110.4L151 A152 M157 G158 A159 M315 L318 A319 L322L151-I155 HydrophobicContact CD1-CD1 4.24Å; L151-I155 HydrophobicContact CD1-CG1 4.39Å; L151-I155 HydrophobicContact CG-CD1 3.96Å; L151-I155 WeakPolarHBondContact O-CG1 3.48Å; L151-I155 PolarHBondContact O-N 3.45Å; A152-I155 PolarHBondContact O-N 2.89Å; I155-M157 VanDerWaalsContact C-N 3.34Å; I155-M157 PolarHBondContact O-N 3.05Å; I155-G158 PolarHBondContact O-N 2.88Å; I155-A159 PolarHBondContact O-N 3.49Å; I155-M315 HydrophobicContact CG2-CB 3.86Å; I155-M315 HydrophobicContact CG2-CE 4.25Å; I155-M315 HydrophobicContact CG2-CG 4.4Å; I155-M315 VanDerWaalsContact CG2-O 3.28Å; I155-M315 WeakPolarHBondContact CG2-O 3.2Å; I155-L318 HydrophobicContact CD1-CD2 4.11Å; I155-L318 HydrophobicContact CD1-CG 4.33Å; I155-A319 HydrophobicContact CB-CB 4.16Å; I155-A319 HydrophobicContact CG2-CB 3.99Å; I155-L322 HydrophobicContact CD1-CD1 3.61Å
156L96.3Very high92Very high0 Ų044.5 Ų44.50%024%0.241CC..Hα-helixtrans-62.2-40.9177.4-166.268.3000112.1I130 A152 L153 G154 A159 G160 L283 F284 S287 I316 A319I130-L156 HydrophobicContact CD1-CG 4.47Å; A152-L156 WeakPolarHBondContact O-CB 3.44Å; A152-L156 PolarHBondContact O-N 3.16Å; L153-L156 HydrophobicContact CD2-CD2 4.47Å; L153-L156 PolarHBondContact O-N 2.78Å; G154-L156 VanDerWaalsContact C-N 3.33Å; G154-L156 PolarHBondContact O-N 3.01Å; L156-A159 PolarHBondContact O-N 2.88Å; L156-G160 PolarHBondContact O-N 3.45Å; L156-G160 VanDerWaalsContact O-N 3.14Å; L156-L283 HydrophobicContact CD2-CB 4.21Å; L156-F284 HydrophobicContact CD1-CD1 3.79Å; L156-F284 HydrophobicContact CD1-CE1 3.77Å; L156-F284 HydrophobicContact CD2-CD1 3.96Å; L156-F284 HydrophobicContact CD2-CD2 4.38Å; L156-F284 HydrophobicContact CD2-CE1 3.94Å; L156-F284 HydrophobicContact CD2-CE2 4.37Å; L156-F284 HydrophobicContact CD2-CG 4.18Å; L156-F284 HydrophobicContact CD2-CZ 4.16Å; L156-F284 HydrophobicContact CG-CE1 4.37Å; L156-S287 VanDerWaalsContact CD1-CB 3.49Å; L156-S287 WeakPolarHBondContact CD1-OG 3.5Å; L156-S287 WeakPolarHBondContact CG-OG 3.49Å; L156-I316 HydrophobicContact CD1-CG1 4.28Å; L156-I316 HydrophobicContact CD1-CG2 4.48Å; L156-A319 HydrophobicContact CB-CB 4.11Å; L156-A319 HydrophobicContact CD1-CB 4.23Å
157M95.6Very high90.9Very high52 Ų5237.7 Ų37.726%0.25622%0.221SC..Hα-helixtrans-63.6-45.6173.3179.6-177.8135.700111.5N127 L128 I130 A131 L153 G154 I155 A159 G160 V161N127-M157 HydrophobicContact CB-CG 4.36Å; L128-M157 HydrophobicContact CD1-CE 4Å; L128-M157 HydrophobicContact CG-CE 4.33Å; I130-M157 HydrophobicContact CB-CB 4.27Å; I130-M157 HydrophobicContact CD1-CB 4.3Å; I130-M157 HydrophobicContact CG2-CB 4.21Å; A131-M157 HydrophobicContact CB-SD 4.05Å; L153-M157 WeakPolarHBondContact O-CB 3.05Å; L153-M157 PolarHBondContact O-N 3.38Å; G154-M157 PolarHBondContact O-N 3.29Å; I155-M157 VanDerWaalsContact C-N 3.34Å; I155-M157 PolarHBondContact O-N 3.05Å; M157-A159 VanDerWaalsContact C-N 3.31Å; M157-A159 PolarHBondContact O-N 3.39Å; M157-G160 PolarHBondContact O-N 3.32Å; M157-V161 WeakPolarHBondContact O-CG2 3.33Å; M157-V161 PolarHBondContact O-N 3.39Å
158G94.4Very high89.5Confident22 Ų2236.5 Ų36.523%0.22721%0.206CC..Hα-helixtrans-58.1-42.8175.200000112.3G154 I155 G160 V161 C162G154-G158 PolarHBondContact O-N 2.91Å; I155-G158 PolarHBondContact O-N 2.88Å; G158-G160 VanDerWaalsContact C-N 3.31Å; G158-G160 PolarHBondContact O-N 2.93Å; G158-V161 PolarHBondContact O-N 3.3Å; G158-C162 WeakPolarHBondContact O-CB 3.33Å; G158-C162 PolarHBondContact O-N 3.19Å; G158-C162 PolarHBondContact O-SG 3.25Å
159A93.8Very high87.7Confident0 Ų039.8 Ų39.80%022%0.217CC..Hα-helixtrans-60-42.2176.100000112.1I155 L156 M157 C162 H163 M315 I316I155-A159 PolarHBondContact O-N 3.49Å; L156-A159 PolarHBondContact O-N 2.88Å; M157-A159 VanDerWaalsContact C-N 3.31Å; M157-A159 PolarHBondContact O-N 3.39Å; A159-C162 PolarHBondContact O-N 2.95Å; A159-H163 WeakPolarHBondContact O-CB 3.34Å; A159-H163 PolarHBondContact O-N 2.92Å; A159-M315 HydrophobicContact CB-CB 3.65Å; A159-M315 HydrophobicContact CB-SD 4.4Å; A159-I316 HydrophobicContact CB-CD1 4.48Å; A159-I316 HydrophobicContact CB-CG1 3.77Å
160G91.1Very high86Confident0 Ų040.2 Ų40.20%022%0.22CC..Hα-helixtrans-61.9-43175.900000112.7N127 L156 M157 G158 S164N127-G160 VanDerWaalsContact CG-C 3.48Å; N127-G160 VanDerWaalsContact ND2-C 3.34Å; N127-G160 PolarHBondContact ND2-O 3.08Å; N127-G160 WeakPolarHBondContact OD1-CA 3.49Å; L156-G160 PolarHBondContact O-N 3.45Å; L156-G160 VanDerWaalsContact O-N 3.14Å; M157-G160 PolarHBondContact O-N 3.32Å; G158-G160 VanDerWaalsContact C-N 3.31Å; G158-G160 PolarHBondContact O-N 2.93Å; G160-S164 WeakPolarHBondContact O-CB 3.3Å; G160-S164 PolarHBondContact O-N 3.37Å; G160-S164 PolarHBondContact O-OG 2.97Å
161V91.3Very high83.5Confident32 Ų3242.4 Ų42.419%0.19424%0.235CC..Hα-helixtrans-62.7-51.7174.7170.30000110.8V124 N127 M157 G158 H163 S164 Y165V124-V161 HydrophobicContact CG1-CG1 4.1Å; N127-V161 HydrophobicContact CB-CG2 3.89Å; M157-V161 WeakPolarHBondContact O-CG2 3.33Å; M157-V161 PolarHBondContact O-N 3.39Å; G158-V161 PolarHBondContact O-N 3.3Å; V161-H163 VanDerWaalsContact C-N 3.32Å; V161-H163 PolarHBondContact O-N 3.09Å; V161-S164 WeakPolarHBondContact O-CB 3.09Å; V161-S164 PolarHBondContact O-N 2.93Å; V161-S164 VanDerWaalsContact O-N 3.08Å; V161-Y165 HydrophobicContact CG1-CD2 3.69Å; V161-Y165 HydrophobicContact CG1-CE2 3.65Å; V161-Y165 WeakPolarHBondContact O-CD2 3.26Å; V161-Y165 PolarHBondContact O-N 3.41Å
162C90.2Very high81.3Confident41 Ų4142.7 Ų42.728%0.27723%0.229SC..Hα-helixtrans-58.4-42.2179.5-68.90000112.3G158 A159 Y165 S166 P312G158-C162 WeakPolarHBondContact O-CB 3.33Å; G158-C162 PolarHBondContact O-N 3.19Å; G158-C162 PolarHBondContact O-SG 3.25Å; A159-C162 PolarHBondContact O-N 2.95Å; C162-Y165 PolarHBondContact O-N 3.03Å; C162-S166 WeakPolarHBondContact O-CB 3.41Å; C162-S166 PolarHBondContact O-N 3.37Å; C162-P312 HydrophobicContact CB-CG 3.82Å
163H87.6Confident78.5Confident13 Ų1349 Ų496%0.0627%0.27CS..Hα-helixtrans-65.9-41175.3177.488.8000111.9A159 V161 Y165 S166 S167 M290 P312A159-H163 WeakPolarHBondContact O-CB 3.34Å; A159-H163 PolarHBondContact O-N 2.92Å; V161-H163 VanDerWaalsContact C-N 3.32Å; V161-H163 PolarHBondContact O-N 3.09Å; H163-Y165 VanDerWaalsContact C-N 3.32Å; H163-Y165 PolarHBondContact O-N 3.07Å; H163-S166 PolarHBondContact O-N 2.9Å; H163-S167 WeakPolarHBondContact O-CB 3.47Å; H163-S167 PolarHBondContact O-N 3.48Å; H163-S167 PolarHBondContact O-OG 3.43Å; H163-M290 HydrophobicContact CB-CE 3.44Å; H163-M290 VanDerWaalsContact CB-CE 3.44Å; H163-M290 WeakPolarHBondContact CD2-CE 3.31Å; H163-M290 PolarHBondContact CE1-O 3.19Å; H163-P312 HydrophobicContact CB-CB 4.01Å; H163-P312 HydrophobicContact CB-CG 3.96Å
164S85.9Confident76.2Confident2 Ų252.6 Ų52.61%0.01431%0.308CS..Hα-helixtrans-59.6-46.3177.9-55.50000110.3N127 G160 V161 S167 L168N127-S164 PolarHBondContact ND2-OG 3.42Å; N127-S164 VanDerWaalsContact ND2-OG 3.14Å; G160-S164 WeakPolarHBondContact O-CB 3.3Å; G160-S164 PolarHBondContact O-N 3.37Å; G160-S164 PolarHBondContact O-OG 2.97Å; V161-S164 WeakPolarHBondContact O-CB 3.09Å; V161-S164 PolarHBondContact O-N 2.93Å; V161-S164 VanDerWaalsContact O-N 3.08Å; S164-S167 PolarHBondContact O-N 3.36Å; S164-S167 PolarHBondContact O-OG 2.91Å; S164-L168 WeakPolarHBondContact O-CG 3.5Å; S164-L168 PolarHBondContact O-N 2.72Å
165Y81.8Confident73.6Confident120 Ų12056.4 Ų56.447%0.47131%0.314SS..Hα-helixtrans-59.7-48.8173.3-86.7-76.8000112.7V124 V161 C162 H163 S167 L168V124-Y165 HydrophobicContact CB-CE2 4.43Å; V124-Y165 HydrophobicContact CG1-CD2 4.44Å; V124-Y165 HydrophobicContact CG1-CE2 3.7Å; V124-Y165 HydrophobicContact CG2-CD2 3.92Å; V124-Y165 HydrophobicContact CG2-CE2 3.78Å; V124-Y165 HydrophobicContact CG2-CG 4.36Å; V161-Y165 HydrophobicContact CG1-CD2 3.69Å; V161-Y165 HydrophobicContact CG1-CE2 3.65Å; V161-Y165 WeakPolarHBondContact O-CD2 3.26Å; V161-Y165 PolarHBondContact O-N 3.41Å; C162-Y165 PolarHBondContact O-N 3.03Å; H163-Y165 VanDerWaalsContact C-N 3.32Å; H163-Y165 PolarHBondContact O-N 3.07Å; Y165-S167 PolarHBondContact O-N 3.14Å; Y165-L168 WeakPolarHBondContact O-CB 3.29Å; Y165-L168 PolarHBondContact O-N 3.33Å
166S76.1Confident70.8Confident14 Ų1460.2 Ų60.210%0.09834%0.339CS..Hα-helixtrans-61.5-29.5179.2178.50000113C162 H163 L168 D169 T306C162-S166 WeakPolarHBondContact O-CB 3.41Å; C162-S166 PolarHBondContact O-N 3.37Å; H163-S166 PolarHBondContact O-N 2.9Å; S166-L168 VanDerWaalsContact C-N 3.27Å; S166-D169 PolarHBondContact O-N 3.45Å; S166-T306 PolarHBondContact OG-OG1 3.32Å
167S68.5Low68.3Low33 Ų3367.9 Ų67.923%0.23138%0.375CS..Hα-helixtrans-74.6-17.1177.766.20000113.7Q123 H163 S164 Y165Q123-S167 PolarHBondContact NE2-OG 3Å; H163-S167 WeakPolarHBondContact O-CB 3.47Å; H163-S167 PolarHBondContact O-N 3.48Å; H163-S167 PolarHBondContact O-OG 3.43Å; S164-S167 PolarHBondContact O-N 3.36Å; S164-S167 PolarHBondContact O-OG 2.91Å; Y165-S167 PolarHBondContact O-N 3.14Å
168L64.6Low65.7Low81 Ų8172.3 Ų72.342%0.42440%0.4SS..Hα-helixtrans-78-30.5174.1-55-178.6000112S120 S164 Y165 S166 L170S120-L168 VanDerWaalsContact CB-CD2 3.47Å; S164-L168 WeakPolarHBondContact O-CG 3.5Å; S164-L168 PolarHBondContact O-N 2.72Å; Y165-L168 WeakPolarHBondContact O-CB 3.29Å; Y165-L168 PolarHBondContact O-N 3.33Å; S166-L168 VanDerWaalsContact C-N 3.27Å; L168-L170 VanDerWaalsContact C-N 3.28Å
169D55.4Low63.3Low115 Ų11577.5 Ų77.562%0.61542%0.418SS*.SBendtrans-83.6-2.3179.5-12014.3000113S166 E171S166-D169 PolarHBondContact O-N 3.45Å; D169-E171 VanDerWaalsContact C-N 3.34Å; D169-E171 PolarHBondContact O-N 3.33Å
170L57.3Low61Low43 Ų4382 Ų8223%0.22546%0.455CS..  trans-74.992175.8-69.4175.7000109.2L168 Y172 Q304 T306L168-L170 VanDerWaalsContact C-N 3.28Å; L170-Y172 PolarHBondContact O-N 2.88Å; L170-Q304 WeakPolarHBondContact CD2-O 3.37Å; L170-T306 HydrophobicContact CD2-CG2 4.19Å
171E42.4Very low58.7Low142 Ų14287 Ų8766%0.66449%0.49SS*.  trans-61.6112.1179.3-145.3155.5172.700110.5D169D169-E171 VanDerWaalsContact C-N 3.34Å; D169-E171 PolarHBondContact O-N 3.33Å
172Y50.8Low56.4Low108 Ų10889.2 Ų89.242%0.42451%0.507SS..  trans-72.9128.3163.6-85.3-95.7000107.4L170 G174 Q175 L303L170-Y172 PolarHBondContact O-N 2.88Å; Y172-G174 PolarHBondContact O-N 3.27Å; Y172-Q175 PolarHBondContact O-N 2.9Å; Y172-L303 HydrophobicContact CD1-CD2 4.28Å; Y172-L303 HydrophobicContact CD2-CD2 4.22Å; Y172-L303 HydrophobicContact CE1-CD2 4.11Å; Y172-L303 HydrophobicContact CE2-CD2 4.04Å; Y172-L303 HydrophobicContact CG-CD2 4.35Å
173P37Very low54.6Low132 Ų13297.8 Ų97.886%0.85753%0.534SS*.THydrogen-bonded Turntrans-60.7106.8177.722.7-30.5000109.3
174G46.5Very low53.4Low80 Ų80102 Ų10283%0.82556%0.556SS**THydrogen-bonded Turntrans1320.8178.200000117.6Y172Y172-G174 PolarHBondContact O-N 3.27Å
175Q42.9Very low52.6Low126 Ų126108.9 Ų108.959%0.58958%0.582SS**  trans-97.8119172.5-71.9-171.5-30.700111.2Y172Y172-Q175 PolarHBondContact O-N 2.9Å
176T37Very low52.5Low109 Ų109106.6 Ų106.667%0.66958%0.577SS**  trans-58.5137.8173.812.40000112.1D178 Q179T176-D178 PolarHBondContact O-N 3.37Å; T176-Q179 PolarHBondContact O-N 3.26Å
177E44.8Very low53Low160 Ų160108.8 Ų108.875%0.74859%0.59SS**THydrogen-bonded Turntrans-53.2-20.5-175.8-65.2-179.2160.500114.9Q179E177-Q179 VanDerWaalsContact C-N 3.34Å; E177-Q179 PolarHBondContact O-N 3Å
178D39.8Very low53.9Low146 Ų146111 Ų11178%0.78161%0.61SS**THydrogen-bonded Turntrans-74.4-12.6-179.5-81.4-29.6000115.2T176T176-D178 PolarHBondContact O-N 3.37Å
179Q45.3Very low55.2Low130 Ų130115.6 Ų115.661%0.60762%0.622SS**THydrogen-bonded Turntrans-98.2-24.1178.2-74.7-170-1000114.5T176 E177 S181 S182T176-Q179 PolarHBondContact O-N 3.26Å; E177-Q179 VanDerWaalsContact C-N 3.34Å; E177-Q179 PolarHBondContact O-N 3Å; Q179-S181 PolarHBondContact O-N 3.46Å; Q179-S182 PolarHBondContact O-N 3.25Å; Q179-S182 PolarHBondContact O-OG 3.12Å
180A45.3Very low56.8Low96 Ų96110.1 Ų110.179%0.79359%0.592SS**THydrogen-bonded Turntrans-72.4-27.7-172.300000114
181S42.3Very low58.4Low103 Ų103111.9 Ų111.972%0.7260%0.602SS**THydrogen-bonded Turntrans-96.95.1179.553.10000113.4Q179 R183Q179-S181 PolarHBondContact O-N 3.46Å; S181-R183 VanDerWaalsContact C-N 3.34Å; S181-R183 PolarHBondContact O-N 2.87Å
182S43.1Very low60.8Low79 Ų79108.6 Ų108.655%0.55259%0.591SS**SBendtrans-83.873.4-170.767.50000113.5Q179Q179-S182 PolarHBondContact O-N 3.25Å; Q179-S182 PolarHBondContact O-OG 3.12Å
183R51.9Low62.9Low222 Ų222104.8 Ų104.884%0.83858%0.578SS**  trans57.9108.5156.7-52.1-176-163.1-150.43116.4S181 R185S181-R183 VanDerWaalsContact C-N 3.34Å; S181-R183 PolarHBondContact O-N 2.87Å; R183-R185 PolarHBondContact O-N 3.41Å
184L62.1Low65.6Low101 Ų10198.5 Ų98.553%0.52954%0.537SS..  trans-46.2107.1154-76.7100.9000108.3S121 I186S121-L184 WeakPolarHBondContact OG-CB 3.23Å; S121-L184 WeakPolarHBondContact OG-CD2 3.42Å; L184-I186 HydrophobicContact CB-CD1 4.44Å; L184-I186 HydrophobicContact CD2-CD1 4.25Å; L184-I186 PolarHBondContact O-N 3.1Å
185R69.8Low67.9Low147 Ų14799 Ų9956%0.55552%0.52SS*.  trans-97.789.7-178.5-172.8-176.576.1-176.14107.2M117 D118 R183M117-R185 WeakPolarHBondContact CA-O 3.18Å; D118-R185 PolarHBondContact N-O 3.36Å; D118-R185 WeakPolarHBondContact OD1-CA 3.41Å; D118-R185 PolarHBondContact OD1-N 3.32Å; R183-R185 PolarHBondContact O-N 3.41Å
186I79.6Confident70.4Confident72 Ų7295.8 Ų95.837%0.36951%0.509SS..BIsolated β-bridgetrans-110111.9176.3-58.6164.9000108.4M117 S121 L125 L184 L191M117-I186 HydrophobicContact CE-CG1 4.17Å; M117-I186 HydrophobicContact CE-CG2 3.78Å; M117-I186 HydrophobicContact CG-CG1 4.41Å; S121-I186 WeakPolarHBondContact OG-CG1 3.48Å; L125-I186 HydrophobicContact CD1-CD1 4.01Å; L184-I186 HydrophobicContact CB-CD1 4.44Å; L184-I186 HydrophobicContact CD2-CD1 4.25Å; L184-I186 PolarHBondContact O-N 3.1Å; I186-L191 HydrophobicContact CG2-CB 4.37Å
187T86Confident73.2Confident60 Ų6091.6 Ų91.637%0.36848%0.481SS..  trans-78.5150.7166.2-55.40000109.6Y116 W189 G190 L191Y116-T187 PolarHBondContact O-N 3.22Å; Y116-T187 PolarHBondContact O-OG1 3.28Å; T187-W189 HydrophobicContact CG2-CB 4.27Å; T187-W189 PolarHBondContact O-N 3.16Å; T187-G190 WeakPolarHBondContact O-CA 3.31Å; T187-G190 PolarHBondContact O-N 2.93Å; T187-L191 PolarHBondContact O-N 3.32Å; T187-L191 VanDerWaalsContact O-N 3.08Å
188A89Confident75.6Confident79 Ų7984.1 Ų84.165%0.65345%0.447SS*.Hα-helixtrans-53.3-38.9174.800000112.4G190 L191 V192A188-G190 PolarHBondContact O-N 3.4Å; A188-L191 WeakPolarHBondContact O-CB 3.48Å; A188-L191 PolarHBondContact O-N 3.18Å; A188-V192 PolarHBondContact O-N 2.95Å; A188-V192 VanDerWaalsContact O-N 3.11Å
189W90Very high78.3Confident178 Ų17882.2 Ų82.267%0.67443%0.432SS*.Hα-helixtrans-61.7-40.1171.8-76.9113.7000113.2Y116 T187 L191 V192 L193Y116-W189 HydrophobicContact CD1-CB 4.28Å; T187-W189 HydrophobicContact CG2-CB 4.27Å; T187-W189 PolarHBondContact O-N 3.16Å; W189-L191 VanDerWaalsContact C-N 3.28Å; W189-L191 PolarHBondContact O-N 3.41Å; W189-V192 PolarHBondContact O-N 3.38Å; W189-L193 WeakPolarHBondContact O-CB 3.07Å; W189-L193 VanDerWaalsContact O-CG 3.25Å; W189-L193 WeakPolarHBondContact O-CG 3.42Å; W189-L193 PolarHBondContact O-N 3.27Å
190G89.6Confident80.7Confident0 Ų077 Ų770%041%0.408CS..Hα-helixtrans-60.7-37.6174.100000112.5T187 A188 L193 V194T187-G190 WeakPolarHBondContact O-CA 3.31Å; T187-G190 PolarHBondContact O-N 2.93Å; A188-G190 PolarHBondContact O-N 3.4Å; G190-L193 PolarHBondContact O-N 2.9Å; G190-V194 PolarHBondContact O-N 3.28Å
191L90.8Very high83Confident80 Ų8073 Ų7342%0.41937%0.374SS..Hα-helixtrans-64.7-44.7174.2-174.668.1000111.9L125 I186 T187 A188 W189 L193 V194 L195L125-L191 HydrophobicContact CD1-CD1 4.48Å; I186-L191 HydrophobicContact CG2-CB 4.37Å; T187-L191 PolarHBondContact O-N 3.32Å; T187-L191 VanDerWaalsContact O-N 3.08Å; A188-L191 WeakPolarHBondContact O-CB 3.48Å; A188-L191 PolarHBondContact O-N 3.18Å; W189-L191 VanDerWaalsContact C-N 3.28Å; W189-L191 PolarHBondContact O-N 3.41Å; L191-L193 VanDerWaalsContact C-N 3.34Å; L191-L193 PolarHBondContact O-N 3.1Å; L191-V194 HydrophobicContact CD1-CG1 4.25Å; L191-V194 WeakPolarHBondContact O-CG1 3.33Å; L191-V194 PolarHBondContact O-N 2.85Å; L191-L195 WeakPolarHBondContact O-CG 3.47Å; L191-L195 PolarHBondContact O-N 2.97Å
192V94Very high85.5Confident73 Ų7368.1 Ų68.144%0.44234%0.34SS..Hα-helixtrans-61.7-45.2175.8175.40000110.5A188 W189 V194 L195 V196A188-V192 PolarHBondContact O-N 2.95Å; A188-V192 VanDerWaalsContact O-N 3.11Å; W189-V192 PolarHBondContact O-N 3.38Å; V192-V194 PolarHBondContact O-N 3.3Å; V192-L195 PolarHBondContact O-N 2.89Å; V192-V196 WeakPolarHBondContact O-CG2 3.47Å; V192-V196 PolarHBondContact O-N 3.47Å
193L93.6Very high88Confident28 Ų2866.6 Ų66.615%0.14733%0.325CS..Hα-helixtrans-63.1-39179.6-68170.4000112.4L109 L112 M113 Y116 W189 G190 L191 L195 V196 Y197L109-L193 HydrophobicContact CD1-CD2 3.8Å; L112-L193 HydrophobicContact CD2-CD2 4.34Å; M113-L193 HydrophobicContact CG-CB 3.63Å; M113-L193 HydrophobicContact CG-CD1 4.3Å; M113-L193 HydrophobicContact SD-CB 4.27Å; Y116-L193 HydrophobicContact CD2-CD1 3.49Å; Y116-L193 VanDerWaalsContact CD2-CD1 3.49Å; Y116-L193 HydrophobicContact CE2-CD1 3.95Å; Y116-L193 HydrophobicContact CG-CD1 4.2Å; W189-L193 WeakPolarHBondContact O-CB 3.07Å; W189-L193 VanDerWaalsContact O-CG 3.25Å; W189-L193 WeakPolarHBondContact O-CG 3.42Å; W189-L193 PolarHBondContact O-N 3.27Å; G190-L193 PolarHBondContact O-N 2.9Å; L191-L193 VanDerWaalsContact C-N 3.34Å; L191-L193 PolarHBondContact O-N 3.1Å; L193-L195 VanDerWaalsContact C-N 3.35Å; L193-L195 PolarHBondContact O-N 3.48Å; L193-V196 PolarHBondContact O-N 2.58Å; L193-Y197 VanDerWaalsContact O-CB 3.28Å; L193-Y197 WeakPolarHBondContact O-CB 3.37Å; L193-Y197 PolarHBondContact O-N 3.23Å
194V94.1Very high90Very high0 Ų056 Ų560%029%0.285CS..Hα-helixtrans-67.7-34.717772.80000112.6M113 M117 L125 G190 L191 V192 Y197 C198M113-V194 HydrophobicContact CE-CB 3.32Å; M113-V194 HydrophobicContact CE-CG2 3.67Å; M117-V194 HydrophobicContact CE-CB 4.44Å; M117-V194 HydrophobicContact CE-CG1 4.29Å; L125-V194 HydrophobicContact CB-CG1 4.14Å; L125-V194 HydrophobicContact CB-CG2 3.79Å; L125-V194 HydrophobicContact CD1-CG1 4.2Å; G190-V194 PolarHBondContact O-N 3.28Å; L191-V194 HydrophobicContact CD1-CG1 4.25Å; L191-V194 WeakPolarHBondContact O-CG1 3.33Å; L191-V194 PolarHBondContact O-N 2.85Å; V192-V194 PolarHBondContact O-N 3.3Å; V194-Y197 WeakPolarHBondContact O-CB 3.31Å; V194-Y197 PolarHBondContact O-N 3.02Å; V194-C198 WeakPolarHBondContact O-CB 3.25Å; V194-C198 PolarHBondContact O-N 3.22Å; V194-C198 PolarHBondContact O-SG 3.17Å
195L95Very high91.5Very high90 Ų9051.5 Ų51.547%0.47126%0.262SS..Hα-helixtrans-66.7-44.6175.3-67.9174.9000110.9L128 L191 V192 L193 Y197 C198 F199L128-L195 HydrophobicContact CD2-CD2 3.96Å; L191-L195 WeakPolarHBondContact O-CG 3.47Å; L191-L195 PolarHBondContact O-N 2.97Å; V192-L195 PolarHBondContact O-N 2.89Å; L193-L195 VanDerWaalsContact C-N 3.35Å; L193-L195 PolarHBondContact O-N 3.48Å; L195-Y197 VanDerWaalsContact C-N 3.32Å; L195-Y197 PolarHBondContact O-N 3.1Å; L195-C198 PolarHBondContact O-N 3.32Å; L195-F199 WeakPolarHBondContact O-CB 3.31Å; L195-F199 PolarHBondContact O-N 3.49Å
196V95.9Very high92.7Very high58 Ų5844.6 Ų44.635%0.35224%0.236SC..Hα-helixtrans-60.7-43.7173.2174.20000110.6L109 V192 L193 C198 F199 I200L109-V196 HydrophobicContact CD2-CB 4.36Å; L109-V196 HydrophobicContact CD2-CG1 3.94Å; V192-V196 WeakPolarHBondContact O-CG2 3.47Å; V192-V196 PolarHBondContact O-N 3.47Å; L193-V196 PolarHBondContact O-N 2.58Å; V196-C198 PolarHBondContact O-N 2.98Å; V196-F199 PolarHBondContact O-N 3.01Å; V196-I200 HydrophobicContact CG1-CD1 3.61Å; V196-I200 HydrophobicContact CG1-CG1 4.28Å; V196-I200 WeakPolarHBondContact O-CB 3.39Å; V196-I200 VanDerWaalsContact O-CG1 3.29Å; V196-I200 WeakPolarHBondContact O-CG1 3.28Å; V196-I200 PolarHBondContact O-N 3.21Å
197Y95.6Very high93.4Very high21 Ų2144.8 Ų44.88%0.08223%0.233CC..Hα-helixtrans-58.6-48.7176168.7-95.4000112.3N106 L109 V110 M113 F122 L193 V194 L195 F199 I200 S201N106-Y197 WeakPolarHBondContact ND2-CD2 3.26Å; N106-Y197 VanDerWaalsContact ND2-CE2 3.25Å; N106-Y197 WeakPolarHBondContact ND2-CE2 3.45Å; N106-Y197 PolarHBondContact ND2-O 3.31Å; N106-Y197 WeakPolarHBondContact OD1-CE2 3.35Å; L109-Y197 HydrophobicContact CB-CD2 4.45Å; L109-Y197 VanDerWaalsContact CD2-CA 3.46Å; L109-Y197 HydrophobicContact CD2-CD2 4.45Å; V110-Y197 HydrophobicContact CG2-CD2 3.84Å; V110-Y197 HydrophobicContact CG2-CE2 3.2Å; M113-Y197 HydrophobicContact SD-CD2 4.45Å; M113-Y197 HydrophobicContact SD-CG 4.06Å; F122-Y197 HydrophobicContact CE2-CD1 4.1Å; F122-Y197 AromaticContact CE2-CE1 3.97Å; F122-Y197 HydrophobicContact CE2-CE1 3.97Å; F122-Y197 HydrophobicContact CZ-CE1 4.06Å; L193-Y197 VanDerWaalsContact O-CB 3.28Å; L193-Y197 WeakPolarHBondContact O-CB 3.37Å; L193-Y197 PolarHBondContact O-N 3.23Å; V194-Y197 WeakPolarHBondContact O-CB 3.31Å; V194-Y197 PolarHBondContact O-N 3.02Å; L195-Y197 VanDerWaalsContact C-N 3.32Å; L195-Y197 PolarHBondContact O-N 3.1Å; Y197-F199 VanDerWaalsContact C-N 3.32Å; Y197-F199 PolarHBondContact O-N 3.16Å; Y197-I200 PolarHBondContact O-N 3.25Å; Y197-S201 VanDerWaalsContact O-CB 3.28Å; Y197-S201 WeakPolarHBondContact O-CB 3.47Å; Y197-S201 PolarHBondContact O-N 3.38Å
198C95.3Very high93.8Very high4 Ų442.1 Ų42.13%0.02722%0.217CC..Hα-helixtrans-63.3-41.2179.2-69.40000111.2L128 K129 S132 V194 L195 V196 G202L128-C198 HydrophobicContact CB-CB 4.4Å; K129-C198 HydrophobicContact CB-CB 4.31Å; K129-C198 PolarHBondContact N-SG 2.98Å; K129-C198 VanDerWaalsContact N-SG 3.43Å; S132-C198 PolarHBondContact OG-O 3.02Å; V194-C198 WeakPolarHBondContact O-CB 3.25Å; V194-C198 PolarHBondContact O-N 3.22Å; V194-C198 PolarHBondContact O-SG 3.17Å; L195-C198 PolarHBondContact O-N 3.32Å; V196-C198 PolarHBondContact O-N 2.98Å; C198-G202 PolarHBondContact O-N 3.46Å
199F96Very high94.1Very high106 Ų10638.4 Ų38.447%0.46519%0.186SC..Hα-helixtrans-62-49.9176.3-177.3-100.8000112.4S132 L136 L195 V196 Y197 S201 G202 L203S132-F199 WeakPolarHBondContact OG-CA 3.49Å; L136-F199 HydrophobicContact CD1-CD2 4.2Å; L136-F199 HydrophobicContact CD1-CE2 4.19Å; L136-F199 HydrophobicContact CD2-CE2 3.91Å; L136-F199 HydrophobicContact CD2-CZ 4.42Å; L136-F199 HydrophobicContact CG-CE2 4.47Å; L195-F199 WeakPolarHBondContact O-CB 3.31Å; L195-F199 PolarHBondContact O-N 3.49Å; V196-F199 PolarHBondContact O-N 3.01Å; Y197-F199 VanDerWaalsContact C-N 3.32Å; Y197-F199 PolarHBondContact O-N 3.16Å; F199-S201 PolarHBondContact O-N 3.39Å; F199-G202 PolarHBondContact O-N 3.46Å; F199-L203 HydrophobicContact CE1-CD2 4.23Å; F199-L203 WeakPolarHBondContact O-CB 3.49Å; F199-L203 PolarHBondContact O-N 3.42Å
200I96Very high94.4Very high20 Ų2036.7 Ų36.710%0.10318%0.179CC..Hα-helixtrans-66.3-39.5180-67.2176.4000111L102 F105 N106 V196 Y197 G202 L203 A204L102-I200 HydrophobicContact CB-CG2 4.41Å; L102-I200 HydrophobicContact CD2-CG2 4.07Å; F105-I200 HydrophobicContact CD1-CD1 3.34Å; F105-I200 HydrophobicContact CD1-CG2 4.28Å; F105-I200 HydrophobicContact CE1-CD1 3.25Å; F105-I200 HydrophobicContact CZ-CD1 4.49Å; N106-I200 HydrophobicContact CB-CG2 4.08Å; V196-I200 HydrophobicContact CG1-CD1 3.61Å; V196-I200 HydrophobicContact CG1-CG1 4.28Å; V196-I200 WeakPolarHBondContact O-CB 3.39Å; V196-I200 VanDerWaalsContact O-CG1 3.29Å; V196-I200 WeakPolarHBondContact O-CG1 3.28Å; V196-I200 PolarHBondContact O-N 3.21Å; Y197-I200 PolarHBondContact O-N 3.25Å; I200-G202 VanDerWaalsContact C-N 3.33Å; I200-G202 PolarHBondContact O-N 2.83Å; I200-L203 PolarHBondContact O-N 3.42Å; I200-A204 VanDerWaalsContact O-CB 3.29Å; I200-A204 WeakPolarHBondContact O-CB 3.37Å; I200-A204 PolarHBondContact O-N 2.98Å
201S94.4Very high94.6Very high13 Ų1337 Ų379%0.09118%0.181CC..Hα-helixtrans-59-45.5174.3176.50000111.2N106 Y197 F199 A205N106-S201 PolarHBondContact ND2-N 3.44Å; Y197-S201 VanDerWaalsContact O-CB 3.28Å; Y197-S201 WeakPolarHBondContact O-CB 3.47Å; Y197-S201 PolarHBondContact O-N 3.38Å; F199-S201 PolarHBondContact O-N 3.39Å; S201-A205 PolarHBondContact O-N 3.45Å
202G93.9Very high94.7Very high0 Ų033.2 Ų33.20%016%0.161CC..Hα-helixtrans-65.8-43.4177.100000112.2T133 C198 F199 I200 A205 V206T133-G202 WeakPolarHBondContact OG1-CA 3.36Å; C198-G202 PolarHBondContact O-N 3.46Å; F199-G202 PolarHBondContact O-N 3.46Å; I200-G202 VanDerWaalsContact C-N 3.33Å; I200-G202 PolarHBondContact O-N 2.83Å; G202-A205 PolarHBondContact O-N 3.31Å; G202-V206 WeakPolarHBondContact O-CB 3.2Å; G202-V206 WeakPolarHBondContact O-CG2 3.47Å; G202-V206 PolarHBondContact O-N 2.83Å
203L95.8Very high94.7Very high47 Ų4733.8 Ų33.825%0.24616%0.158CC..Hα-helixtrans-63.7-44.2179.3-175.763.2000111.3L102 L136 F199 I200 A205 V206 Y207L102-L203 HydrophobicContact CD1-CD2 4.28Å; L102-L203 HydrophobicContact CD1-CG 4.07Å; L102-L203 HydrophobicContact CD2-CD2 4.25Å; L136-L203 HydrophobicContact CD1-CB 4.06Å; L136-L203 VanDerWaalsContact CD1-N 3.29Å; F199-L203 HydrophobicContact CE1-CD2 4.23Å; F199-L203 WeakPolarHBondContact O-CB 3.49Å; F199-L203 PolarHBondContact O-N 3.42Å; I200-L203 PolarHBondContact O-N 3.42Å; L203-A205 VanDerWaalsContact C-N 3.34Å; L203-A205 PolarHBondContact O-N 3.19Å; L203-V206 PolarHBondContact O-N 3.06Å; L203-Y207 WeakPolarHBondContact O-CB 3.41Å; L203-Y207 PolarHBondContact O-N 2.85Å
204A94.4Very high94.6Very high0 Ų036.3 Ų36.30%018%0.178CC..Hα-helixtrans-57.3-48.1175.600000111.1L102 Y103 I200 T208L102-A204 HydrophobicContact CB-CB 3.7Å; L102-A204 HydrophobicContact CD1-CB 4.37Å; Y103-A204 HydrophobicContact CD1-CB 3.87Å; Y103-A204 HydrophobicContact CE1-CB 3.65Å; Y103-A204 HydrophobicContact CE2-CB 4.42Å; Y103-A204 HydrophobicContact CG-CB 4.32Å; I200-A204 VanDerWaalsContact O-CB 3.29Å; I200-A204 WeakPolarHBondContact O-CB 3.37Å; I200-A204 PolarHBondContact O-N 2.98Å; A204-T208 VanDerWaalsContact O-CB 3.29Å; A204-T208 WeakPolarHBondContact O-CB 3.31Å; A204-T208 PolarHBondContact O-N 3.08Å; A204-T208 PolarHBondContact O-OG1 3.44Å
205A92.6Very high94.3Very high5 Ų537.9 Ų37.94%0.04119%0.185CC..Hα-helixtrans-62.2-48.9-179.900000112.1T133 S201 G202 L203 T208 E209T133-A205 HydrophobicContact CG2-CB 4.44Å; S201-A205 PolarHBondContact O-N 3.45Å; G202-A205 PolarHBondContact O-N 3.31Å; L203-A205 VanDerWaalsContact C-N 3.34Å; L203-A205 PolarHBondContact O-N 3.19Å; A205-T208 PolarHBondContact O-N 3.39Å; A205-E209 PolarHBondContact O-N 2.88Å
206V94.8Very high93.9Very high2 Ų245.8 Ų45.81%0.01221%0.209CC..Hα-helixtrans-69.2-39.5-177.4171.40000111.9T133 L136 C140 L141 G202 L203 E209 R210T133-V206 HydrophobicContact CG2-CG2 4.36Å; L136-V206 HydrophobicContact CB-CB 4.43Å; L136-V206 HydrophobicContact CB-CG2 3.91Å; C140-V206 HydrophobicContact CB-CG1 3.79Å; L141-V206 HydrophobicContact CD1-CG1 3.76Å; L141-V206 HydrophobicContact CG-CG1 3.84Å; G202-V206 WeakPolarHBondContact O-CB 3.2Å; G202-V206 WeakPolarHBondContact O-CG2 3.47Å; G202-V206 PolarHBondContact O-N 2.83Å; L203-V206 PolarHBondContact O-N 3.06Å; V206-E209 PolarHBondContact O-N 2.87Å; V206-R210 WeakPolarHBondContact O-CB 3.37Å; V206-R210 PolarHBondContact O-N 2.92Å
207Y95.2Very high93.5Very high77 Ų7744.7 Ų44.730%0.30220%0.201SC..Hα-helixtrans-68.3-42.2176.3-163.3-76000111.1P95 V98 P99 L203 E209 R210 V211P95-Y207 WeakPolarHBondContact O-CE1 3.24Å; V98-Y207 HydrophobicContact CB-CD1 4.32Å; V98-Y207 HydrophobicContact CB-CE1 3.74Å; V98-Y207 HydrophobicContact CG1-CD1 4.13Å; V98-Y207 HydrophobicContact CG1-CD2 4.33Å; V98-Y207 HydrophobicContact CG1-CE1 3.85Å; V98-Y207 HydrophobicContact CG1-CE2 4.1Å; V98-Y207 HydrophobicContact CG1-CG 4.34Å; V98-Y207 HydrophobicContact CG2-CE1 4.48Å; P99-Y207 HydrophobicContact CG-CD1 3.65Å; P99-Y207 HydrophobicContact CG-CE1 4.2Å; L203-Y207 WeakPolarHBondContact O-CB 3.41Å; L203-Y207 PolarHBondContact O-N 2.85Å; Y207-E209 VanDerWaalsContact C-N 3.32Å; Y207-E209 PolarHBondContact O-N 3.28Å; Y207-R210 PolarHBondContact O-N 3.5Å; Y207-R210 VanDerWaalsContact O-N 3.16Å; Y207-V211 HydrophobicContact CD1-CG2 3.51Å; Y207-V211 HydrophobicContact CE1-CG2 3.25Å; Y207-V211 WeakPolarHBondContact O-CG2 3.18Å; Y207-V211 PolarHBondContact O-N 2.82Å
208T94.8Very high93.1Very high4 Ų445.6 Ų45.63%0.02521%0.209CC..Hα-helixtrans-56.9-48.4173.6-54.10000110.4P99 Y103 A204 A205 R210 V211 L212 L274P99-T208 WeakPolarHBondContact CB-OG1 3.34Å; Y103-T208 VanDerWaalsContact CE2-OG1 3.3Å; Y103-T208 WeakPolarHBondContact CE2-OG1 3.37Å; Y103-T208 PolarHBondContact OH-OG1 3.47Å; A204-T208 VanDerWaalsContact O-CB 3.29Å; A204-T208 WeakPolarHBondContact O-CB 3.31Å; A204-T208 PolarHBondContact O-N 3.08Å; A204-T208 PolarHBondContact O-OG1 3.44Å; A205-T208 PolarHBondContact O-N 3.39Å; T208-R210 VanDerWaalsContact C-N 3.33Å; T208-R210 PolarHBondContact O-N 2.95Å; T208-V211 PolarHBondContact O-N 3.34Å; T208-L212 HydrophobicContact CG2-CD1 3.83Å; T208-L212 HydrophobicContact CG2-CG 4.23Å; T208-L212 WeakPolarHBondContact O-CB 3.39Å; T208-L212 VanDerWaalsContact O-CG 3.25Å; T208-L212 WeakPolarHBondContact O-CG 3.42Å; T208-L212 PolarHBondContact O-N 3.33Å; T208-L274 HydrophobicContact CG2-CD1 3.8Å
209E95.4Very high92.9Very high1 Ų147 Ų471%0.00522%0.216CC..Hα-helixtrans-57.6-45.4176178.6171.9175.600111.8L141 A205 V206 Y207 K213 L274 G279L141-E209 HydrophobicContact CD1-CG 4.18Å; A205-E209 PolarHBondContact O-N 2.88Å; V206-E209 PolarHBondContact O-N 2.87Å; Y207-E209 VanDerWaalsContact C-N 3.32Å; Y207-E209 PolarHBondContact O-N 3.28Å; E209-K213 HydrophobicContact CG-CD 3.9Å; E209-K213 WeakPolarHBondContact O-CB 3.3Å; E209-K213 WeakPolarHBondContact O-CG 3.46Å; E209-K213 PolarHBondContact O-N 3.19Å; E209-K213 IonicContact OE1-NZ 2.72Å; E209-K213 PolarHBondContact OE1-NZ 2.97Å; E209-L274 HydrophobicContact CB-CD2 4.26Å; E209-G279 WeakPolarHBondContact OE2-CA 2.97Å; E209-G279 PolarHBondContact OE2-N 3.32Å
210R94.6Very high92.7Very high141 Ų14142.5 Ų42.553%0.53220%0.198SC..Hα-helixtrans-61.9-46.7179.6-174.4174.1175.1153.9-6.6112.2C140 L141 V206 Y207 T208 K213 S214C140-R210 PolarHBondContact O-NH1 2.66Å; L141-R210 HydrophobicContact CD2-CB 3.89Å; L141-R210 HydrophobicContact CD2-CG 4.29Å; V206-R210 WeakPolarHBondContact O-CB 3.37Å; V206-R210 PolarHBondContact O-N 2.92Å; Y207-R210 PolarHBondContact O-N 3.5Å; Y207-R210 VanDerWaalsContact O-N 3.16Å; T208-R210 VanDerWaalsContact C-N 3.33Å; T208-R210 PolarHBondContact O-N 2.95Å; R210-K213 PolarHBondContact O-N 3.44Å; R210-S214 VanDerWaalsContact O-CB 3.23Å; R210-S214 WeakPolarHBondContact O-CB 3.24Å; R210-S214 PolarHBondContact O-N 3.43Å; R210-S214 PolarHBondContact O-OG 3.49Å
211V94.4Very high92.4Very high6 Ų641.7 Ų41.74%0.03619%0.194CC..Hα-helixtrans-66.9-45.8-179.9173.30000111.2P95 Y96 Y207 T208 K213 S214P95-V211 HydrophobicContact CB-CG1 4.11Å; P95-V211 HydrophobicContact CB-CG2 4.04Å; Y96-V211 HydrophobicContact CD1-CG1 3.64Å; Y96-V211 HydrophobicContact CD2-CG1 4.37Å; Y96-V211 HydrophobicContact CE1-CG1 3.39Å; Y96-V211 HydrophobicContact CE2-CG1 4.16Å; Y96-V211 HydrophobicContact CG-CG1 4.12Å; Y207-V211 HydrophobicContact CD1-CG2 3.51Å; Y207-V211 HydrophobicContact CE1-CG2 3.25Å; Y207-V211 WeakPolarHBondContact O-CG2 3.18Å; Y207-V211 PolarHBondContact O-N 2.82Å; T208-V211 PolarHBondContact O-N 3.34Å; V211-K213 VanDerWaalsContact C-N 3.29Å; V211-K213 PolarHBondContact O-N 2.79Å; V211-S214 PolarHBondContact O-N 3.18Å; V211-S214 PolarHBondContact O-OG 3.34Å; V211-S214 VanDerWaalsContact O-OG 3.1Å
212L93.6Very high92.3Very high2 Ų241 Ų411%0.0119%0.189CC..Hα-helixtrans-59-43.9177.3-71.3177.3000110.3Y96 T208 L219 Q222 L274 K275Y96-L212 HydrophobicContact CE1-CD2 4.35Å; T208-L212 HydrophobicContact CG2-CD1 3.83Å; T208-L212 HydrophobicContact CG2-CG 4.23Å; T208-L212 WeakPolarHBondContact O-CB 3.39Å; T208-L212 VanDerWaalsContact O-CG 3.25Å; T208-L212 WeakPolarHBondContact O-CG 3.42Å; T208-L212 PolarHBondContact O-N 3.33Å; L212-L219 HydrophobicContact CD2-CD1 4.11Å; L212-Q222 HydrophobicContact CD2-CB 3.76Å; L212-Q222 VanDerWaalsContact CD2-OE1 3.26Å; L212-Q222 PolarHBondContact O-NE2 2.95Å; L212-Q222 PolarHBondContact O-OE1 3.3Å; L212-L274 HydrophobicContact CD1-CB 3.85Å; L212-K275 HydrophobicContact CB-CB 4.43Å; L212-K275 HydrophobicContact CB-CD 4Å; L212-K275 WeakPolarHBondContact O-CD 3.39Å; L212-K275 WeakPolarHBondContact O-CE 2.96Å; L212-K275 PolarHBondContact O-NZ 2.67Å
213K94.3Very high92.3Very high85 Ų8541.4 Ų41.437%0.3719%0.191SC..Hα-helixtrans-78.6-26.4-177.8-70.8-178.7179.5177.10114.9E209 R210 V211 L274 K275 G277E209-K213 HydrophobicContact CG-CD 3.9Å; E209-K213 WeakPolarHBondContact O-CB 3.3Å; E209-K213 WeakPolarHBondContact O-CG 3.46Å; E209-K213 PolarHBondContact O-N 3.19Å; E209-K213 IonicContact OE1-NZ 2.72Å; E209-K213 PolarHBondContact OE1-NZ 2.97Å; R210-K213 PolarHBondContact O-N 3.44Å; V211-K213 VanDerWaalsContact C-N 3.29Å; V211-K213 PolarHBondContact O-N 2.79Å; K213-L274 WeakPolarHBondContact CE-O 3.2Å; K213-K275 VanDerWaalsContact CE-O 3.32Å; K213-K275 WeakPolarHBondContact CE-O 3.36Å; K213-G277 PolarHBondContact NZ-O 2.95Å
214S90.9Very high92.1Very high81 Ų8140.1 Ų40.157%0.56619%0.185SC*.Hα-helixtrans-74.2-32.5-176.464.20000113R210 V211R210-S214 VanDerWaalsContact O-CB 3.23Å; R210-S214 WeakPolarHBondContact O-CB 3.24Å; R210-S214 PolarHBondContact O-N 3.43Å; R210-S214 PolarHBondContact O-OG 3.49Å; V211-S214 PolarHBondContact O-N 3.18Å; V211-S214 PolarHBondContact O-OG 3.34Å; V211-S214 VanDerWaalsContact O-OG 3.1Å
215Q87.4Confident92Very high33 Ų3341.2 Ų41.215%0.15419%0.189CC..SBendtrans-97.2136.6-176.4-62.6-166.50.100112.8L92 Y96 L217 Q222 K275L92-Q215 PolarHBondContact O-NE2 2.74Å; Y96-Q215 PolarHBondContact OH-OE1 3.36Å; Q215-L217 HydrophobicContact CB-CD1 4.34Å; Q215-L217 HydrophobicContact CB-CG 4.29Å; Q215-L217 PolarHBondContact O-N 2.98Å; Q215-L217 VanDerWaalsContact O-N 3.12Å; Q215-Q222 PolarHBondContact O-NE2 3.37Å; Q215-Q222 VanDerWaalsContact O-NE2 3.08Å; Q215-K275 PolarHBondContact O-NZ 3.14Å; Q215-K275 VanDerWaalsContact O-NZ 3.1Å
216R85.8Confident92Very high255 Ų25541.7 Ų41.796%0.96219%0.191SC*.  trans-86.151.7176-62.7-173.6-178179.51.9111.8
217L87.4Confident91.9Very high36 Ų3642 Ų4219%0.18819%0.192CC..SBendtrans-108152.8176.8-61.5174.7000110.7L92 Q215 L221 Q222 Y225L92-L217 HydrophobicContact CD1-CD1 4.03Å; L92-L217 HydrophobicContact CD1-CD2 4.32Å; L92-L217 HydrophobicContact CD2-CD1 3.63Å; L92-L217 HydrophobicContact CG-CD1 3.91Å; Q215-L217 HydrophobicContact CB-CD1 4.34Å; Q215-L217 HydrophobicContact CB-CG 4.29Å; Q215-L217 PolarHBondContact O-N 2.98Å; Q215-L217 VanDerWaalsContact O-N 3.12Å; L217-L221 HydrophobicContact CD2-CD2 4.39Å; L217-Q222 HydrophobicContact CB-CG 3.76Å; L217-Q222 HydrophobicContact CD1-CG 4.43Å; L217-Y225 HydrophobicContact CD1-CE2 4.23Å
218P89.1Confident91.8Very high40 Ų4041.7 Ų41.726%0.2620%0.198SC..  trans-59.5139.9170.625.2-32.1000109.9L75 D80 S220 L221 Q222L75-P218 HydrophobicContact CD1-CG 4.46Å; D80-P218 HydrophobicContact CB-CG 4.31Å; P218-S220 VanDerWaalsContact C-N 3.26Å; P218-S220 PolarHBondContact O-N 3.29Å; P218-L221 HydrophobicContact CG-CB 3.87Å; P218-L221 HydrophobicContact CG-CD2 4.4Å; P218-L221 PolarHBondContact O-N 3.45Å; P218-L221 VanDerWaalsContact O-N 3.1Å; P218-Q222 PolarHBondContact O-N 3.3Å; P218-Q222 VanDerWaalsContact O-N 3.16Å
219L91Very high91.7Very high32 Ų3244.2 Ų44.217%0.16821%0.209CC..Hα-helixtrans-60.5-35.9-174-179.363.5000112.3L212 L221 Q222 N223 V272 K275L212-L219 HydrophobicContact CD2-CD1 4.11Å; L219-L221 VanDerWaalsContact C-N 3.29Å; L219-L221 PolarHBondContact O-N 3.47Å; L219-Q222 PolarHBondContact O-N 3.35Å; L219-N223 VanDerWaalsContact O-CB 3.3Å; L219-N223 WeakPolarHBondContact O-CB 3.46Å; L219-N223 PolarHBondContact O-N 3.14Å; L219-V272 HydrophobicContact CD2-CB 4.23Å; L219-V272 HydrophobicContact CD2-CG2 3.57Å; L219-K275 HydrophobicContact CD1-CB 3.88Å; L219-K275 HydrophobicContact CD1-CD 4.38Å; L219-K275 HydrophobicContact CD1-CG 4.06Å
220S90.6Very high91.4Very high13 Ų1344.5 Ų44.59%0.09121%0.212CC..Hα-helixtrans-58-41176.246.40000112.1L75 P218 L224L75-S220 WeakPolarHBondContact CD1-OG 3.19Å; P218-S220 VanDerWaalsContact C-N 3.26Å; P218-S220 PolarHBondContact O-N 3.29Å; S220-L224 WeakPolarHBondContact O-CB 3.09Å; S220-L224 PolarHBondContact O-N 2.83Å
221L90.4Very high91.3Very high2 Ų239.6 Ų39.61%0.0120%0.196CC..Hα-helixtrans-71.6-40.5176.5-173.265.6000112.4L75 A83 L84 L217 P218 L219 N223 L224 Y225L75-L221 HydrophobicContact CD1-CB 4.22Å; L75-L221 HydrophobicContact CD2-CD1 3.93Å; A83-L221 HydrophobicContact CB-CD2 3.69Å; L84-L221 HydrophobicContact CD2-CD1 4.49Å; L217-L221 HydrophobicContact CD2-CD2 4.39Å; P218-L221 HydrophobicContact CG-CB 3.87Å; P218-L221 HydrophobicContact CG-CD2 4.4Å; P218-L221 PolarHBondContact O-N 3.45Å; P218-L221 VanDerWaalsContact O-N 3.1Å; L219-L221 VanDerWaalsContact C-N 3.29Å; L219-L221 PolarHBondContact O-N 3.47Å; L221-N223 VanDerWaalsContact C-N 3.31Å; L221-N223 PolarHBondContact O-N 3.49Å; L221-L224 HydrophobicContact CD1-CD2 4.22Å; L221-L224 WeakPolarHBondContact O-CB 3.49Å; L221-L224 PolarHBondContact O-N 3.21Å; L221-Y225 HydrophobicContact CD1-CE1 4.15Å; L221-Y225 HydrophobicContact CD1-CE2 4.26Å; L221-Y225 HydrophobicContact CD2-CE2 4.21Å; L221-Y225 HydrophobicContact CG-CD2 4.49Å; L221-Y225 HydrophobicContact CG-CE2 3.78Å; L221-Y225 WeakPolarHBondContact O-CD2 3.44Å; L221-Y225 PolarHBondContact O-N 3.39Å; L221-Y225 VanDerWaalsContact O-N 3.08Å
222Q92.5Very high91.2Very high0 Ų041.7 Ų41.70%021%0.214CC..Hα-helixtrans-61.1-42.7175.1-61.4-169-29.300111.5Y96 L212 Q215 L217 P218 L219 Y225 L226Y96-Q222 HydrophobicContact CE1-CB 3.78Å; Y96-Q222 HydrophobicContact CE1-CG 4.23Å; Y96-Q222 VanDerWaalsContact OH-CG 3.3Å; Y96-Q222 WeakPolarHBondContact OH-CG 3.45Å; Y96-Q222 PolarHBondContact OH-NE2 3.28Å; L212-Q222 HydrophobicContact CD2-CB 3.76Å; L212-Q222 VanDerWaalsContact CD2-OE1 3.26Å; L212-Q222 PolarHBondContact O-NE2 2.95Å; L212-Q222 PolarHBondContact O-OE1 3.3Å; Q215-Q222 PolarHBondContact O-NE2 3.37Å; Q215-Q222 VanDerWaalsContact O-NE2 3.08Å; L217-Q222 HydrophobicContact CB-CG 3.76Å; L217-Q222 HydrophobicContact CD1-CG 4.43Å; P218-Q222 PolarHBondContact O-N 3.3Å; P218-Q222 VanDerWaalsContact O-N 3.16Å; L219-Q222 PolarHBondContact O-N 3.35Å; Q222-Y225 PolarHBondContact O-N 2.85Å; Q222-L226 WeakPolarHBondContact O-CB 3.07Å; Q222-L226 PolarHBondContact O-N 3.2Å
223N93Very high91Very high7 Ų744 Ų444%0.03723%0.226CC..Hα-helixtrans-62.7-42.3174-83.2-4.7000111.6L219 L221 Y225 L226 Y227 S271L219-N223 VanDerWaalsContact O-CB 3.3Å; L219-N223 WeakPolarHBondContact O-CB 3.46Å; L219-N223 PolarHBondContact O-N 3.14Å; L221-N223 VanDerWaalsContact C-N 3.31Å; L221-N223 PolarHBondContact O-N 3.49Å; N223-Y225 PolarHBondContact O-N 2.87Å; N223-L226 PolarHBondContact O-N 3.36Å; N223-Y227 HydrophobicContact CB-CD2 4.05Å; N223-Y227 HydrophobicContact CB-CE2 3.53Å; N223-Y227 WeakPolarHBondContact O-CB 3.37Å; N223-Y227 WeakPolarHBondContact O-CD2 3.26Å; N223-Y227 PolarHBondContact O-N 3Å; N223-S271 WeakPolarHBondContact OD1-CB 3.05Å; N223-S271 PolarHBondContact OD1-OG 2.9Å
224L92.1Very high90.6Very high20 Ų2041.3 Ų41.311%0.10522%0.215CC..Hα-helixtrans-55.1-50.9175.2-165.481.3000110.9L68 L72 L75 L84 S220 L221 L226 Y227 V228L68-L224 HydrophobicContact CD1-CD1 3.52Å; L68-L224 HydrophobicContact CD1-CG 4.1Å; L68-L224 HydrophobicContact CG-CD1 4.29Å; L72-L224 HydrophobicContact CB-CD1 4.02Å; L72-L224 HydrophobicContact CD1-CD1 4.45Å; L75-L224 HydrophobicContact CD2-CD2 4.5Å; L84-L224 HydrophobicContact CD2-CD2 4.33Å; S220-L224 WeakPolarHBondContact O-CB 3.09Å; S220-L224 PolarHBondContact O-N 2.83Å; L221-L224 HydrophobicContact CD1-CD2 4.22Å; L221-L224 WeakPolarHBondContact O-CB 3.49Å; L221-L224 PolarHBondContact O-N 3.21Å; L224-L226 PolarHBondContact O-N 3.41Å; L224-Y227 PolarHBondContact O-N 2.91Å; L224-V228 VanDerWaalsContact O-CG2 3.27Å; L224-V228 WeakPolarHBondContact O-CG2 3.21Å; L224-V228 PolarHBondContact O-N 3.48Å
225Y92.1Very high90.5Very high23 Ų2341.3 Ų41.39%0.0921%0.208CC..Hα-helixtrans-60.8-44.5177.9-61.9-34.7000112.6L88 L92 V93 Y96 L217 L221 Q222 N223 Y227 V228 F229L88-Y225 HydrophobicContact CD2-CE1 3.77Å; L92-Y225 HydrophobicContact CD2-CE2 3.63Å; V93-Y225 HydrophobicContact CG1-CD1 4.19Å; V93-Y225 HydrophobicContact CG1-CG 4.29Å; V93-Y225 HydrophobicContact CG2-CD1 4.22Å; V93-Y225 HydrophobicContact CG2-CD2 4.39Å; V93-Y225 HydrophobicContact CG2-CE1 4.01Å; V93-Y225 HydrophobicContact CG2-CE2 4.17Å; V93-Y225 HydrophobicContact CG2-CG 4.42Å; Y96-Y225 AromaticContact CD2-CD2 3.98Å; Y96-Y225 HydrophobicContact CD2-CD2 3.98Å; Y96-Y225 HydrophobicContact CD2-CG 4.32Å; Y96-Y225 AromaticContact CE2-CD2 3.82Å; Y96-Y225 HydrophobicContact CE2-CD2 3.82Å; L217-Y225 HydrophobicContact CD1-CE2 4.23Å; L221-Y225 HydrophobicContact CD1-CE1 4.15Å; L221-Y225 HydrophobicContact CD1-CE2 4.26Å; L221-Y225 HydrophobicContact CD2-CE2 4.21Å; L221-Y225 HydrophobicContact CG-CD2 4.49Å; L221-Y225 HydrophobicContact CG-CE2 3.78Å; L221-Y225 WeakPolarHBondContact O-CD2 3.44Å; L221-Y225 PolarHBondContact O-N 3.39Å; L221-Y225 VanDerWaalsContact O-N 3.08Å; Q222-Y225 PolarHBondContact O-N 2.85Å; N223-Y225 PolarHBondContact O-N 2.87Å; Y225-Y227 PolarHBondContact O-N 2.9Å; Y225-V228 PolarHBondContact O-N 3.39Å; Y225-F229 WeakPolarHBondContact O-CD2 3.42Å; Y225-F229 PolarHBondContact O-N 3.46Å
226L91.7Very high90.5Very high15 Ų1543.7 Ų43.78%0.07923%0.225CC..Hα-helixtrans-60.1-46.8178.6-175.468.5000112Y96 P99 Q222 N223 L224 F229 G230Y96-L226 HydrophobicContact CD1-CB 4.42Å; P99-L226 HydrophobicContact CB-CD1 3.61Å; P99-L226 HydrophobicContact CG-CD1 4.33Å; Q222-L226 WeakPolarHBondContact O-CB 3.07Å; Q222-L226 PolarHBondContact O-N 3.2Å; N223-L226 PolarHBondContact O-N 3.36Å; L224-L226 PolarHBondContact O-N 3.41Å; L226-F229 PolarHBondContact O-N 3.36Å; L226-G230 PolarHBondContact O-N 3.44Å
227Y93.1Very high90.3Very high9 Ų933 Ų334%0.03519%0.19CC..Hα-helixtrans-77.8-25.2-176.2-55.7-39000113K67 S71 N223 L224 Y225 G230 L231 G267 L268 S271K67-Y227 HydrophobicContact CB-CD1 4.25Å; K67-Y227 HydrophobicContact CB-CD2 3.63Å; K67-Y227 HydrophobicContact CB-CE1 4.35Å; K67-Y227 HydrophobicContact CB-CE2 3.7Å; K67-Y227 HydrophobicContact CB-CG 3.93Å; K67-Y227 HydrophobicContact CD-CD1 3.98Å; K67-Y227 HydrophobicContact CD-CE1 3.68Å; K67-Y227 HydrophobicContact CD-CE2 4.36Å; K67-Y227 HydrophobicContact CD-CG 4.49Å; K67-Y227 HydrophobicContact CG-CE2 4.4Å; S71-Y227 WeakPolarHBondContact OG-CE2 3.32Å; N223-Y227 HydrophobicContact CB-CD2 4.05Å; N223-Y227 HydrophobicContact CB-CE2 3.53Å; N223-Y227 WeakPolarHBondContact O-CB 3.37Å; N223-Y227 WeakPolarHBondContact O-CD2 3.26Å; N223-Y227 PolarHBondContact O-N 3Å; L224-Y227 PolarHBondContact O-N 2.91Å; Y225-Y227 PolarHBondContact O-N 2.9Å; Y227-G230 PolarHBondContact O-N 2.92Å; Y227-L231 WeakPolarHBondContact O-CB 3.45Å; Y227-L231 PolarHBondContact O-N 3Å; Y227-G267 PolarHBondContact OH-O 3.44Å; Y227-L268 HydrophobicContact CE2-CD2 3.63Å; Y227-S271 PolarHBondContact OH-OG 3.49Å
228V93.5Very high90Very high71 Ų7132.4 Ų32.443%0.4319%0.186SC..Hα-helixtrans-61.6-47.8169.51670000110.5L68 L224 Y225 L231 A232L68-V228 HydrophobicContact CD1-CG2 3.61Å; L224-V228 VanDerWaalsContact O-CG2 3.27Å; L224-V228 WeakPolarHBondContact O-CG2 3.21Å; L224-V228 PolarHBondContact O-N 3.48Å; Y225-V228 PolarHBondContact O-N 3.39Å; V228-L231 PolarHBondContact O-N 3.28Å; V228-A232 WeakPolarHBondContact O-CB 3.34Å; V228-A232 PolarHBondContact O-N 2.98Å
229F92.9Very high89.7Confident57 Ų5735.9 Ų35.925%0.2520%0.202CC..Hα-helixtrans-66.8-40175.5-71.6-65.3000112.1V93 A97 A100 Y225 L226 A232 I233V93-F229 HydrophobicContact CG1-CE2 3.6Å; V93-F229 HydrophobicContact CG1-CZ 3.83Å; V93-F229 WeakPolarHBondContact O-CE2 3.27Å; A97-F229 HydrophobicContact CB-CD1 3.79Å; A97-F229 HydrophobicContact CB-CD2 3.91Å; A97-F229 HydrophobicContact CB-CE1 3.82Å; A97-F229 HydrophobicContact CB-CE2 3.93Å; A97-F229 HydrophobicContact CB-CG 3.85Å; A97-F229 HydrophobicContact CB-CZ 3.89Å; A100-F229 HydrophobicContact CB-CB 3.6Å; Y225-F229 WeakPolarHBondContact O-CD2 3.42Å; Y225-F229 PolarHBondContact O-N 3.46Å; L226-F229 PolarHBondContact O-N 3.36Å; F229-A232 PolarHBondContact O-N 3.17Å; F229-I233 VanDerWaalsContact O-CG1 3.31Å; F229-I233 WeakPolarHBondContact O-CG1 3.38Å; F229-I233 PolarHBondContact O-N 3.4Å
230G89.9Confident89.3Confident7 Ų741.3 Ų41.37%0.07223%0.23CC..Hα-helixtrans-57.6-48.3174.800000112.3L226 Y227 I233 N234L226-G230 PolarHBondContact O-N 3.44Å; Y227-G230 PolarHBondContact O-N 2.92Å; G230-I233 PolarHBondContact O-N 3.23Å; G230-N234 WeakPolarHBondContact O-CB 3.36Å; G230-N234 PolarHBondContact O-N 3.14Å; G230-N234 PolarHBondContact O-ND2 2.88Å
231L92Very high88.3Confident37 Ų3744.8 Ų44.819%0.19426%0.255CS..Hα-helixtrans-61.5-46.7176.918060.5000111.5L61 E64 I65 L68 Y227 V228 I233 N234 L235L61-L231 HydrophobicContact CD2-CD1 3.86Å; E64-L231 HydrophobicContact CB-CB 4.43Å; E64-L231 HydrophobicContact CB-CD1 4.37Å; I65-L231 HydrophobicContact CD1-CD1 4.33Å; I65-L231 HydrophobicContact CG1-CD1 3.68Å; I65-L231 HydrophobicContact CG1-CD2 4.21Å; L68-L231 HydrophobicContact CD2-CD2 4.08Å; Y227-L231 WeakPolarHBondContact O-CB 3.45Å; Y227-L231 PolarHBondContact O-N 3Å; V228-L231 PolarHBondContact O-N 3.28Å; L231-I233 VanDerWaalsContact C-N 3.35Å; L231-I233 PolarHBondContact O-N 2.98Å; L231-N234 PolarHBondContact O-N 3.29Å; L231-L235 VanDerWaalsContact O-CB 3.23Å; L231-L235 WeakPolarHBondContact O-CB 3.16Å; L231-L235 PolarHBondContact O-N 3.28Å
232A92.3Very high87.1Confident51 Ų5149.3 Ų49.342%0.42128%0.277SS..Hα-helixtrans-58.5-46.1179.500000112V228 F229 L235 V236V228-A232 WeakPolarHBondContact O-CB 3.34Å; V228-A232 PolarHBondContact O-N 2.98Å; F229-A232 PolarHBondContact O-N 3.17Å; A232-L235 PolarHBondContact O-N 3.46Å; A232-V236 WeakPolarHBondContact O-CG2 3.08Å; A232-V236 PolarHBondContact O-N 3.39Å; A232-V236 VanDerWaalsContact O-N 3.08Å
233I88.6Confident85.4Confident50 Ų5053.3 Ų53.326%0.25632%0.318SS..Hα-helixtrans-66.5-46.2179.8-64.2169.2000111A100 A101 A104 F229 G230 L231 L235 V236 S237A100-I233 HydrophobicContact CB-CD1 4.1Å; A101-I233 HydrophobicContact CB-CD1 4.1Å; A104-I233 HydrophobicContact CB-CB 4.37Å; A104-I233 HydrophobicContact CB-CG2 3.39Å; F229-I233 VanDerWaalsContact O-CG1 3.31Å; F229-I233 WeakPolarHBondContact O-CG1 3.38Å; F229-I233 PolarHBondContact O-N 3.4Å; G230-I233 PolarHBondContact O-N 3.23Å; L231-I233 VanDerWaalsContact C-N 3.35Å; L231-I233 PolarHBondContact O-N 2.98Å; I233-L235 VanDerWaalsContact C-N 3.28Å; I233-L235 PolarHBondContact O-N 2.96Å; I233-V236 PolarHBondContact O-N 2.78Å; I233-S237 PolarHBondContact O-N 2.97Å; I233-S237 PolarHBondContact O-OG 3.46Å
234N86.3Confident83.6Confident28 Ų2855.1 Ų55.115%0.1534%0.338CS..Hα-helixtrans-65.3-33.2178.9-76.2-72.8000112.1V60 L61 G230 L231 S237 H238V60-N234 VanDerWaalsContact CG1-OD1 3.31Å; V60-N234 WeakPolarHBondContact CG1-OD1 3.29Å; L61-N234 HydrophobicContact CD2-CB 3.67Å; L61-N234 HydrophobicContact CG-CB 4.4Å; G230-N234 WeakPolarHBondContact O-CB 3.36Å; G230-N234 PolarHBondContact O-N 3.14Å; G230-N234 PolarHBondContact O-ND2 2.88Å; L231-N234 PolarHBondContact O-N 3.29Å; N234-S237 PolarHBondContact O-N 3.18Å; N234-H238 WeakPolarHBondContact O-CB 3.37Å; N234-H238 PolarHBondContact O-N 2.68Å
235L88Confident81.8Confident81 Ų8164 Ų6442%0.42438%0.379SS..Hα-helixtrans-66.4-45.5176.9-178.762.9000110.6L61 L231 A232 I233 S237 H238 L239L61-L235 HydrophobicContact CD2-CB 4.22Å; L231-L235 VanDerWaalsContact O-CB 3.23Å; L231-L235 WeakPolarHBondContact O-CB 3.16Å; L231-L235 PolarHBondContact O-N 3.28Å; A232-L235 PolarHBondContact O-N 3.46Å; I233-L235 VanDerWaalsContact C-N 3.28Å; I233-L235 PolarHBondContact O-N 2.96Å; L235-S237 PolarHBondContact O-N 3.36Å; L235-H238 PolarHBondContact O-N 3.43Å; L235-L239 HydrophobicContact CD1-CG 4.47Å; L235-L239 HydrophobicContact CG-CD1 4.23Å; L235-L239 VanDerWaalsContact O-CG 3.28Å; L235-L239 WeakPolarHBondContact O-CG 3.46Å; L235-L239 PolarHBondContact O-N 3.49Å
236V87.7Confident80.4Confident83 Ų8368.9 Ų68.950%0.50340%0.403SS..Hα-helixtrans-59.9-46.3173.7172.80000110.7A232 I233 H238 L239 L240A232-V236 WeakPolarHBondContact O-CG2 3.08Å; A232-V236 PolarHBondContact O-N 3.39Å; A232-V236 VanDerWaalsContact O-N 3.08Å; I233-V236 PolarHBondContact O-N 2.78Å; V236-H238 VanDerWaalsContact C-N 3.29Å; V236-H238 PolarHBondContact O-N 2.81Å; V236-L239 PolarHBondContact O-N 3.09Å; V236-L240 HydrophobicContact CG1-CD1 3.85Å; V236-L240 HydrophobicContact CG1-CG 4.33Å; V236-L240 VanDerWaalsContact O-CG 3.28Å; V236-L240 WeakPolarHBondContact O-CG 3.3Å; V236-L240 PolarHBondContact O-N 2.89Å
237S81.8Confident79.6Confident32 Ų3274.2 Ų74.222%0.22443%0.431CS..Hα-helixtrans-59.5-39.3176.7-63.60000112.8I233 N234 L235 S241I233-S237 PolarHBondContact O-N 2.97Å; I233-S237 PolarHBondContact O-OG 3.46Å; N234-S237 PolarHBondContact O-N 3.18Å; L235-S237 PolarHBondContact O-N 3.36Å; S237-S241 WeakPolarHBondContact O-CB 3.4Å; S237-S241 PolarHBondContact O-N 3.18Å; S237-S241 PolarHBondContact O-OG 3.29Å
238H80.8Confident78.9Confident23 Ų2377.4 Ų77.411%0.10645%0.446CS..Hα-helixtrans-65.1-49.4176.1-175.571.4000111.6S57 L61 N234 L235 V236 L240 S241 M242 F248S57-H238 WeakPolarHBondContact OG-CB 3.3Å; S57-H238 PolarHBondContact OG-ND1 3.44Å; L61-H238 HydrophobicContact CD1-CB 3.63Å; N234-H238 WeakPolarHBondContact O-CB 3.37Å; N234-H238 PolarHBondContact O-N 2.68Å; L235-H238 PolarHBondContact O-N 3.43Å; V236-H238 VanDerWaalsContact C-N 3.29Å; V236-H238 PolarHBondContact O-N 2.81Å; H238-L240 VanDerWaalsContact C-N 3.3Å; H238-L240 PolarHBondContact O-N 3.48Å; H238-S241 CarbonylContact O-C 3.52Å; H238-S241 WeakPolarHBondContact O-CA 3.29Å; H238-S241 PolarHBondContact O-N 2.94Å; H238-M242 VanDerWaalsContact O-CG 3.31Å; H238-M242 WeakPolarHBondContact O-CG 3.48Å; H238-M242 PolarHBondContact O-N 3.44Å; H238-F248 AromaticContact NE2-CD2 3.81Å
239L84.1Confident78.5Confident112 Ų11278.5 Ų78.559%0.58645%0.449SS*.Hα-helixtrans-59.9-38.9179.2-68.7173000112.3L235 V236 S241 M242L235-L239 HydrophobicContact CD1-CG 4.47Å; L235-L239 HydrophobicContact CG-CD1 4.23Å; L235-L239 VanDerWaalsContact O-CG 3.28Å; L235-L239 WeakPolarHBondContact O-CG 3.46Å; L235-L239 PolarHBondContact O-N 3.49Å; V236-L239 PolarHBondContact O-N 3.09Å; L239-S241 VanDerWaalsContact C-N 3.26Å; L239-S241 PolarHBondContact O-N 2.94Å; L239-M242 PolarHBondContact O-N 3.4Å
240L81.2Confident78Confident146 Ų14680.8 Ų80.876%0.76446%0.46SS*.Hα-helixtrans-70.4-22.7175.6-67173.3000113.1V236 H238V236-L240 HydrophobicContact CG1-CD1 3.85Å; V236-L240 HydrophobicContact CG1-CG 4.33Å; V236-L240 VanDerWaalsContact O-CG 3.28Å; V236-L240 WeakPolarHBondContact O-CG 3.3Å; V236-L240 PolarHBondContact O-N 2.89Å; H238-L240 VanDerWaalsContact C-N 3.3Å; H238-L240 PolarHBondContact O-N 3.48Å
241S70.8Confident77.5Confident87 Ų8782.1 Ų82.161%0.60847%0.474SS*.THydrogen-bonded Turntrans-92.8-1.2180-55.20000113.2S237 H238 L239 G243S237-S241 WeakPolarHBondContact O-CB 3.4Å; S237-S241 PolarHBondContact O-N 3.18Å; S237-S241 PolarHBondContact O-OG 3.29Å; H238-S241 CarbonylContact O-C 3.52Å; H238-S241 WeakPolarHBondContact O-CA 3.29Å; H238-S241 PolarHBondContact O-N 2.94Å; L239-S241 VanDerWaalsContact C-N 3.26Å; L239-S241 PolarHBondContact O-N 2.94Å; S241-G243 PolarHBondContact O-N 3.23Å
242M65.2Low77.3Confident97 Ų9782 Ų8248%0.47847%0.471SS..  trans-73.855.7179.8-73.2-9753.900112.5H238 L239 G244H238-M242 VanDerWaalsContact O-CG 3.31Å; H238-M242 WeakPolarHBondContact O-CG 3.48Å; H238-M242 PolarHBondContact O-N 3.44Å; L239-M242 PolarHBondContact O-N 3.4Å; M242-G244 WeakPolarHBondContact CE-O 3.28Å
243G57Low77.1Confident83 Ų8382 Ų8286%0.85647%0.468SS*.  trans-98.410169.800000113.7S241S241-G243 PolarHBondContact O-N 3.23Å
244G55.4Low77.1Confident46 Ų4682.7 Ų82.747%0.47449%0.487SS..SBendtrans-147.3134.5179.500000112.4M242 Q246M242-G244 WeakPolarHBondContact CE-O 3.28Å; G244-Q246 VanDerWaalsContact C-N 3.27Å; G244-Q246 PolarHBondContact O-N 3.34Å
245E53.9Low77.2Confident205 Ų20583.9 Ų83.996%0.95850%0.495SS*.  trans-6972177.2-59.6-177.7152.900111.4
246Q62.2Low77.4Confident127 Ų12780 Ų8059%0.59348%0.475SS*.  trans-111129.3164.8-79.7-176-12.800109.1G244G244-Q246 VanDerWaalsContact C-N 3.27Å; G244-Q246 PolarHBondContact O-N 3.34Å
247D74.3Confident77.7Confident126 Ų12682 Ų8267%0.67447%0.473SS*.  trans-64.8139.9178.3-83.7-23.1000110.1L249 E250D247-L249 PolarHBondContact O-N 2.96Å; D247-E250 HydrophobicContact CB-CB 4.03Å; D247-E250 PolarHBondContact N-OE2 3.24Å; D247-E250 WeakPolarHBondContact O-CB 3.45Å; D247-E250 PolarHBondContact O-N 3.31Å
248F80.2Confident78.2Confident77 Ų7782.9 Ų82.934%0.33848%0.483SS..THydrogen-bonded Turntrans-55.5-32.5-171.9-176.1-99.5000113.6S58 L61 L62 H238S58-F248 WeakPolarHBondContact CB-O 3.2Å; S58-F248 WeakPolarHBondContact OG-CD2 3.07Å; S58-F248 PolarHBondContact OG-O 2.97Å; L61-F248 HydrophobicContact CB-CZ 4.32Å; L61-F248 HydrophobicContact CD1-CE2 3.94Å; L61-F248 HydrophobicContact CD1-CZ 4.44Å; L62-F248 HydrophobicContact CD1-CE1 4.37Å; L62-F248 HydrophobicContact CD2-CE1 4.16Å; L62-F248 HydrophobicContact CG-CE1 4.1Å; L62-F248 HydrophobicContact CG-CZ 4.31Å; H238-F248 AromaticContact NE2-CD2 3.81Å
249L83.4Confident78.8Confident94 Ų9482.1 Ų82.149%0.49248%0.479SS..THydrogen-bonded Turntrans-112.115.9-178.2-59.8178.7000113.5L62 D247 Y252L62-L249 HydrophobicContact CD1-CD2 3.91Å; D247-L249 PolarHBondContact O-N 2.96Å; L249-Y252 WeakPolarHBondContact O-CD2 3.23Å
250E82.6Confident79.3Confident105 Ų10576.9 Ų76.949%0.49145%0.452SS..THydrogen-bonded Turntrans-64.6137.7178.7-155.4179.7163.300111.4F54 D247 Y252F54-E250 WeakPolarHBondContact CA-O 3.44Å; D247-E250 HydrophobicContact CB-CB 4.03Å; D247-E250 PolarHBondContact N-OE2 3.24Å; D247-E250 WeakPolarHBondContact O-CB 3.45Å; D247-E250 PolarHBondContact O-N 3.31Å; E250-Y252 VanDerWaalsContact C-N 3.3Å; E250-Y252 WeakPolarHBondContact O-CD2 3.45Å; E250-Y252 PolarHBondContact O-N 3.34Å
251G80.9Confident80Confident35 Ų3572.6 Ų72.636%0.36144%0.438SS..THydrogen-bonded Turntrans759.8176.900000115.8S253G251-S253 PolarHBondContact O-N 3Å
252Y85.9Confident81.2Confident35 Ų3569.3 Ų69.314%0.13742%0.417CS..  trans-76.5107.5177.7-83.4-113.8000111.7F54 C59 L62 L249 E250 V256 W257 V260F54-Y252 HydrophobicContact CB-CD2 3.95Å; F54-Y252 HydrophobicContact CB-CE2 3.73Å; C59-Y252 WeakPolarHBondContact CA-OH 3.44Å; C59-Y252 WeakPolarHBondContact CB-OH 3.35Å; C59-Y252 PolarHBondContact N-OH 3.46Å; L62-Y252 HydrophobicContact CD1-CD1 4.34Å; L62-Y252 HydrophobicContact CD1-CE1 3.41Å; L62-Y252 VanDerWaalsContact CD1-CE1 3.41Å; L249-Y252 WeakPolarHBondContact O-CD2 3.23Å; E250-Y252 VanDerWaalsContact C-N 3.3Å; E250-Y252 WeakPolarHBondContact O-CD2 3.45Å; E250-Y252 PolarHBondContact O-N 3.34Å; Y252-V256 HydrophobicContact CD1-CB 4.05Å; Y252-V256 HydrophobicContact CD1-CG1 3.42Å; Y252-V256 VanDerWaalsContact CD1-CG1 3.42Å; Y252-V256 HydrophobicContact CE1-CG1 3.46Å; Y252-V256 VanDerWaalsContact CE1-CG1 3.46Å; Y252-V256 HydrophobicContact CG-CB 4.4Å; Y252-V256 HydrophobicContact CG-CG1 3.97Å; Y252-W257 HydrophobicContact CD1-CZ2 4.34Å; Y252-V260 HydrophobicContact CE1-CG2 4.45Å
253S88Confident82.6Confident51 Ų5166.3 Ų66.336%0.35740%0.402SS..  trans-93.2171.4168.974.40000111.7G251 V255 V256 W257G251-S253 PolarHBondContact O-N 3Å; S253-V255 PolarHBondContact O-N 3.32Å; S253-V255 VanDerWaalsContact O-N 3.16Å; S253-V255 PolarHBondContact OG-N 3.41Å; S253-V256 WeakPolarHBondContact O-CB 3.33Å; S253-V256 PolarHBondContact O-N 2.85Å; S253-W257 PolarHBondContact O-N 3.26Å
254G88.8Confident84.4Confident63 Ų6362.5 Ų62.565%0.64936%0.362SS*.Hα-helixtrans-56.2-29.4172.900000113.4W257 A258G254-W257 PolarHBondContact O-N 2.87Å; G254-A258 PolarHBondContact O-N 3.49Å; G254-A258 VanDerWaalsContact O-N 3.1Å
255V89.9Confident86.3Confident53 Ų5362 Ų6232%0.32135%0.354SS..Hα-helixtrans-70.3-36.4175.7-176.10000111.2L42 T46 S253 A258 I259L42-V255 HydrophobicContact CB-CG1 4.26Å; L42-V255 HydrophobicContact CD2-CG1 4.33Å; L42-V255 HydrophobicContact CG-CG1 4.2Å; T46-V255 HydrophobicContact CG2-CB 3.89Å; T46-V255 HydrophobicContact CG2-CG1 3.66Å; S253-V255 PolarHBondContact O-N 3.32Å; S253-V255 VanDerWaalsContact O-N 3.16Å; S253-V255 PolarHBondContact OG-N 3.41Å; V255-A258 WeakPolarHBondContact O-CB 3.38Å; V255-A258 PolarHBondContact O-N 3.21Å; V255-I259 HydrophobicContact CG1-CD1 4.33Å; V255-I259 WeakPolarHBondContact O-CG1 3.28Å; V255-I259 PolarHBondContact O-N 2.88Å
256V91.2Very high88.3Confident0 Ų052.7 Ų52.70%031%0.311CS..Hα-helixtrans-64.1-42.1175.7-174.60000110.6T46 F54 Y252 S253 A258 I259 V260T46-V256 HydrophobicContact CG2-CG2 3.88Å; F54-V256 HydrophobicContact CD1-CB 4.43Å; F54-V256 HydrophobicContact CD1-CG1 3.97Å; F54-V256 HydrophobicContact CD1-CG2 3.5Å; F54-V256 VanDerWaalsContact CD1-CG2 3.5Å; F54-V256 HydrophobicContact CD2-CG1 4.42Å; F54-V256 HydrophobicContact CE1-CG1 4.12Å; F54-V256 HydrophobicContact CE1-CG2 3.69Å; F54-V256 HydrophobicContact CG-CG1 4.13Å; F54-V256 HydrophobicContact CG-CG2 4.35Å; F54-V256 HydrophobicContact CZ-CG1 4.43Å; Y252-V256 HydrophobicContact CD1-CB 4.05Å; Y252-V256 HydrophobicContact CD1-CG1 3.42Å; Y252-V256 VanDerWaalsContact CD1-CG1 3.42Å; Y252-V256 HydrophobicContact CE1-CG1 3.46Å; Y252-V256 VanDerWaalsContact CE1-CG1 3.46Å; Y252-V256 HydrophobicContact CG-CB 4.4Å; Y252-V256 HydrophobicContact CG-CG1 3.97Å; S253-V256 WeakPolarHBondContact O-CB 3.33Å; S253-V256 PolarHBondContact O-N 2.85Å; V256-A258 VanDerWaalsContact C-N 3.32Å; V256-A258 PolarHBondContact O-N 3.33Å; V256-I259 WeakPolarHBondContact O-CB 3.28Å; V256-I259 PolarHBondContact O-N 2.96Å; V256-I259 VanDerWaalsContact O-N 3.13Å; V256-V260 WeakPolarHBondContact O-CG2 3.28Å; V256-V260 PolarHBondContact O-N 2.94Å
257W93.6Very high89.8Confident125 Ų12547.2 Ų47.247%0.47329%0.289SS..Hα-helixtrans-62.7-38173.5-74.3109.3000112.8L62 Y252 S253 G254 I259 V260 A261L62-W257 HydrophobicContact CD1-CH2 4.18Å; L62-W257 HydrophobicContact CD1-CZ3 4.4Å; L62-W257 HydrophobicContact CD2-CH2 4.45Å; Y252-W257 HydrophobicContact CD1-CZ2 4.34Å; S253-W257 PolarHBondContact O-N 3.26Å; G254-W257 PolarHBondContact O-N 2.87Å; W257-I259 VanDerWaalsContact C-N 3.34Å; W257-V260 PolarHBondContact O-N 3Å; W257-A261 WeakPolarHBondContact O-CB 3.42Å; W257-A261 PolarHBondContact O-N 3.3Å
258A93.5Very high90.7Very high51 Ų5142.6 Ų42.642%0.42126%0.264SS..Hα-helixtrans-63.9-38.1172.600000112.2L42 G254 V255 V256 G262L42-A258 HydrophobicContact CD2-CB 4.35Å; G254-A258 PolarHBondContact O-N 3.49Å; G254-A258 VanDerWaalsContact O-N 3.1Å; V255-A258 WeakPolarHBondContact O-CB 3.38Å; V255-A258 PolarHBondContact O-N 3.21Å; V256-A258 VanDerWaalsContact C-N 3.32Å; V256-A258 PolarHBondContact O-N 3.33Å; A258-G262 PolarHBondContact O-N 2.88Å
259I93Very high91.4Very high6 Ų640.5 Ų40.53%0.03126%0.256CS..Hα-helixtrans-62.4-47.9173-69162.5000110.5L42 I43 T46 V255 V256 W257 A261 G262 Q263L42-I259 HydrophobicContact CB-CD1 4.07Å; L42-I259 HydrophobicContact CB-CG1 3.79Å; L42-I259 HydrophobicContact CD2-CG1 4.1Å; I43-I259 HydrophobicContact CG1-CD1 3.83Å; T46-I259 HydrophobicContact CG2-CD1 3.93Å; V255-I259 HydrophobicContact CG1-CD1 4.33Å; V255-I259 WeakPolarHBondContact O-CG1 3.28Å; V255-I259 PolarHBondContact O-N 2.88Å; V256-I259 WeakPolarHBondContact O-CB 3.28Å; V256-I259 PolarHBondContact O-N 2.96Å; V256-I259 VanDerWaalsContact O-N 3.13Å; W257-I259 VanDerWaalsContact C-N 3.34Å; I259-A261 PolarHBondContact O-N 3.11Å; I259-G262 PolarHBondContact O-N 3.44Å; I259-Q263 HydrophobicContact CG2-CG 4.31Å; I259-Q263 WeakPolarHBondContact O-CB 3.38Å; I259-Q263 WeakPolarHBondContact O-CG 3.05Å; I259-Q263 PolarHBondContact O-N 3.26Å
260V94.8Very high91.9Very high2 Ų236.8 Ų36.81%0.01224%0.236CC..Hα-helixtrans-58.8-50.3178.41710000110.7L62 I63 Y252 V256 W257 G262 Q263 A264L62-V260 HydrophobicContact CB-CG1 4.08Å; L62-V260 HydrophobicContact CB-CG2 4.38Å; I63-V260 HydrophobicContact CG1-CB 4.26Å; I63-V260 HydrophobicContact CG1-CG1 4.05Å; I63-V260 HydrophobicContact CG1-CG2 4.28Å; Y252-V260 HydrophobicContact CE1-CG2 4.45Å; V256-V260 WeakPolarHBondContact O-CG2 3.28Å; V256-V260 PolarHBondContact O-N 2.94Å; W257-V260 PolarHBondContact O-N 3Å; V260-G262 PolarHBondContact O-N 3.18Å; V260-Q263 PolarHBondContact O-N 2.97Å; V260-A264 WeakPolarHBondContact O-CB 3.39Å; V260-A264 PolarHBondContact O-N 3.2Å
261A95.8Very high92.5Very high56 Ų5632 Ų3246%0.46322%0.215SC..Hα-helixtrans-62.3-44.5178.600000112W257 I259 A264 A265W257-A261 WeakPolarHBondContact O-CB 3.42Å; W257-A261 PolarHBondContact O-N 3.3Å; I259-A261 PolarHBondContact O-N 3.11Å; A261-A264 PolarHBondContact O-N 2.84Å; A261-A265 WeakPolarHBondContact O-CB 3.45Å; A261-A265 PolarHBondContact O-N 3.29Å
262G95.4Very high93.1Very high18 Ų1832.1 Ų32.119%0.18621%0.208CC..Hα-helixtrans-61.9-47177.200000112.4I35 A258 I259 V260 A264 A265 N266I35-G262 WeakPolarHBondContact CG2-O 3.47Å; A258-G262 PolarHBondContact O-N 2.88Å; I259-G262 PolarHBondContact O-N 3.44Å; V260-G262 PolarHBondContact O-N 3.18Å; G262-A264 PolarHBondContact O-N 2.95Å; G262-A265 PolarHBondContact O-N 3.48Å; G262-N266 VanDerWaalsContact O-CB 3.3Å; G262-N266 WeakPolarHBondContact O-CB 3.23Å; G262-N266 PolarHBondContact O-N 2.89Å
263Q94.8Very high93.5Very high35 Ų3530.4 Ų30.416%0.16420%0.201CC..Hα-helixtrans-67.8-35.4178.4-72.4-54.2-52.800112.8H39 I63 I259 V260 G267H39-Q263 VanDerWaalsContact CD2-CD 3.4Å; H39-Q263 PolarHBondContact CD2-NE2 2.88Å; H39-Q263 VanDerWaalsContact CG-NE2 3.27Å; I63-Q263 HydrophobicContact CD1-CB 3.61Å; I63-Q263 HydrophobicContact CD1-CG 4.09Å; I63-Q263 HydrophobicContact CG1-CB 3.97Å; I63-Q263 HydrophobicContact CG2-CB 4.12Å; I259-Q263 HydrophobicContact CG2-CG 4.31Å; I259-Q263 WeakPolarHBondContact O-CB 3.38Å; I259-Q263 WeakPolarHBondContact O-CG 3.05Å; I259-Q263 PolarHBondContact O-N 3.26Å; V260-Q263 PolarHBondContact O-N 2.97Å; Q263-G267 PolarHBondContact O-N 3.23Å
264A95.7Very high93.8Very high2 Ų228.2 Ų28.22%0.01719%0.185CC..Hα-helixtrans-62.9-49.2171.900000111.2T66 K67 V260 A261 G262 N266 G267 L268T66-A264 HydrophobicContact CG2-CB 3.63Å; K67-A264 HydrophobicContact CG-CB 3.88Å; V260-A264 WeakPolarHBondContact O-CB 3.39Å; V260-A264 PolarHBondContact O-N 3.2Å; A261-A264 PolarHBondContact O-N 2.84Å; G262-A264 PolarHBondContact O-N 2.95Å; A264-N266 PolarHBondContact O-N 3.38Å; A264-G267 PolarHBondContact O-N 3.36Å; A264-L268 WeakPolarHBondContact O-CG 3.26Å; A264-L268 PolarHBondContact O-N 2.85Å
265A95.6Very high94Very high36 Ų3626.9 Ų26.930%0.29816%0.162SC..Hα-helixtrans-59.3-46.8176.600000111.9I35 A261 G262 G267 L268 L269I35-A265 HydrophobicContact CD1-CB 4.2Å; A261-A265 WeakPolarHBondContact O-CB 3.45Å; A261-A265 PolarHBondContact O-N 3.29Å; G262-A265 PolarHBondContact O-N 3.48Å; A265-G267 VanDerWaalsContact C-N 3.33Å; A265-G267 PolarHBondContact O-N 3.25Å; A265-L268 PolarHBondContact O-N 2.94Å; A265-L269 WeakPolarHBondContact O-CB 3.43Å; A265-L269 VanDerWaalsContact O-CG 3.24Å; A265-L269 WeakPolarHBondContact O-CG 3.22Å; A265-L269 PolarHBondContact O-N 3.46Å
266N94.5Very high94.1Very high9 Ų930 Ų305%0.04817%0.173CC..Hα-helixtrans-58.7-43.4176.4176.853.5000111.9I35 Y36 G262 A264 L268 L269 M270I35-N266 HydrophobicContact CG2-CB 3.88Å; Y36-N266 VanDerWaalsContact CD2-ND2 3.26Å; Y36-N266 WeakPolarHBondContact CD2-ND2 3.26Å; G262-N266 VanDerWaalsContact O-CB 3.3Å; G262-N266 WeakPolarHBondContact O-CB 3.23Å; G262-N266 PolarHBondContact O-N 2.89Å; A264-N266 PolarHBondContact O-N 3.38Å; N266-L268 PolarHBondContact O-N 3.43Å; N266-L269 PolarHBondContact O-N 3.48Å; N266-M270 WeakPolarHBondContact O-CB 3.4Å; N266-M270 WeakPolarHBondContact O-CG 3.48Å; N266-M270 PolarHBondContact O-N 2.92Å
267G93.4Very high94Very high13 Ų1331.1 Ų31.113%0.13418%0.184CC..Hα-helixtrans-61.4-42.617600000113.4Y227 Q263 A264 A265 M270 S271Y227-G267 PolarHBondContact OH-O 3.44Å; Q263-G267 PolarHBondContact O-N 3.23Å; A264-G267 PolarHBondContact O-N 3.36Å; A265-G267 VanDerWaalsContact C-N 3.33Å; A265-G267 PolarHBondContact O-N 3.25Å; G267-M270 PolarHBondContact O-N 3.48Å; G267-S271 PolarHBondContact O-N 2.88Å; G267-S271 VanDerWaalsContact O-N 3.15Å; G267-S271 PolarHBondContact O-OG 2.85Å
268L94.6Very high93.8Very high28 Ų2825.7 Ų25.715%0.14717%0.165CC..Hα-helixtrans-65.8-44.9176.7-68.7165.5000111.9K67 V70 S71 Y227 A264 A265 N266 M270 S271 V272K67-L268 HydrophobicContact CG-CG 4.46Å; V70-L268 HydrophobicContact CB-CD1 3.85Å; V70-L268 HydrophobicContact CG1-CD1 3.44Å; V70-L268 VanDerWaalsContact CG1-CD1 3.44Å; S71-L268 WeakPolarHBondContact OG-CD2 3.38Å; Y227-L268 HydrophobicContact CE2-CD2 3.63Å; A264-L268 WeakPolarHBondContact O-CG 3.26Å; A264-L268 PolarHBondContact O-N 2.85Å; A265-L268 PolarHBondContact O-N 2.94Å; N266-L268 PolarHBondContact O-N 3.43Å; L268-M270 VanDerWaalsContact C-N 3.32Å; L268-M270 PolarHBondContact O-N 3.43Å; L268-S271 WeakPolarHBondContact O-CB 3.39Å; L268-S271 PolarHBondContact O-N 3.39Å; L268-V272 PolarHBondContact O-N 3.29Å
269L95Very high93.6Very high33 Ų3323.3 Ų23.317%0.17315%0.146CC..Hα-helixtrans-64.7-36.9176.8-66.9172.3000111.5L28 L31 M32 I35 A265 N266 S271 V272 V273L28-L269 HydrophobicContact CD1-CD2 4.27Å; L28-L269 HydrophobicContact CG-CD2 4.21Å; L31-L269 HydrophobicContact CD2-CD1 4.09Å; L31-L269 HydrophobicContact CG-CD1 4.35Å; M32-L269 HydrophobicContact CE-CB 3.92Å; M32-L269 HydrophobicContact CG-CB 3.58Å; M32-L269 HydrophobicContact CG-CD1 3.68Å; M32-L269 HydrophobicContact CG-CG 4.21Å; M32-L269 HydrophobicContact SD-CB 3.73Å; I35-L269 HydrophobicContact CD1-CD1 4.19Å; A265-L269 WeakPolarHBondContact O-CB 3.43Å; A265-L269 VanDerWaalsContact O-CG 3.24Å; A265-L269 WeakPolarHBondContact O-CG 3.22Å; A265-L269 PolarHBondContact O-N 3.46Å; N266-L269 PolarHBondContact O-N 3.48Å; L269-S271 VanDerWaalsContact C-N 3.33Å; L269-S271 PolarHBondContact O-N 3.2Å; L269-V272 WeakPolarHBondContact O-CA 3.43Å; L269-V272 WeakPolarHBondContact O-CB 3.25Å; L269-V272 PolarHBondContact O-N 3.23Å; L269-V272 VanDerWaalsContact O-N 3.08Å; L269-V273 PolarHBondContact O-N 3.46Å
270M93.8Very high93.6Very high16 Ų1623 Ų238%0.07914%0.144CC..Hα-helixtrans-60.5-41173.1-77.3-68.617900111.7M32 Y36 N266 G267 L268 V272 V273 L274 R282 V285 I286M32-M270 HydrophobicContact CE-CB 4.21Å; M32-M270 HydrophobicContact CE-CE 3.63Å; M32-M270 HydrophobicContact CE-CG 3.56Å; M32-M270 HydrophobicContact CE-SD 3.33Å; M32-M270 WeakPolarHBondContact CE-SD 3.41Å; Y36-M270 HydrophobicContact CD2-CE 4.19Å; Y36-M270 HydrophobicContact CE2-CE 4.48Å; N266-M270 WeakPolarHBondContact O-CB 3.4Å; N266-M270 WeakPolarHBondContact O-CG 3.48Å; N266-M270 PolarHBondContact O-N 2.92Å; G267-M270 PolarHBondContact O-N 3.48Å; L268-M270 VanDerWaalsContact C-N 3.32Å; L268-M270 PolarHBondContact O-N 3.43Å; M270-V272 VanDerWaalsContact C-N 3.3Å; M270-V272 PolarHBondContact O-N 3.38Å; M270-V273 PolarHBondContact O-N 3.48Å; M270-L274 WeakPolarHBondContact O-CB 3.48Å; M270-L274 WeakPolarHBondContact O-CG 3.47Å; M270-L274 PolarHBondContact O-N 3.41Å; M270-R282 HydrophobicContact CE-CG 4.16Å; M270-R282 HydrophobicContact SD-CB 3.98Å; M270-R282 HydrophobicContact SD-CG 3.55Å; M270-R282 VanDerWaalsContact SD-CG 3.55Å; M270-V285 HydrophobicContact CE-CG1 4.01Å; M270-I286 HydrophobicContact CE-CG1 4.08Å
271S93.5Very high93.5Very high5 Ų523.6 Ų23.64%0.03515%0.148CC..Hα-helixtrans-61.8-36.9172.7-65.20000112.5N223 Y227 G267 L268 L269 L274 K275N223-S271 WeakPolarHBondContact OD1-CB 3.05Å; N223-S271 PolarHBondContact OD1-OG 2.9Å; Y227-S271 PolarHBondContact OH-OG 3.49Å; G267-S271 PolarHBondContact O-N 2.88Å; G267-S271 VanDerWaalsContact O-N 3.15Å; G267-S271 PolarHBondContact O-OG 2.85Å; L268-S271 WeakPolarHBondContact O-CB 3.39Å; L268-S271 PolarHBondContact O-N 3.39Å; L269-S271 VanDerWaalsContact C-N 3.33Å; L269-S271 PolarHBondContact O-N 3.2Å; S271-L274 PolarHBondContact O-N 3.08Å; S271-K275 VanDerWaalsContact O-CB 3.25Å; S271-K275 WeakPolarHBondContact O-CB 3.28Å; S271-K275 PolarHBondContact O-N 2.96Å
272V94.4Very high93.4Very high37 Ų3723 Ų2322%0.22413%0.134CC..Hα-helixtrans-63.3-46174.4178.80000111L28 L219 L268 L269 M270 K275 H276L28-V272 HydrophobicContact CD1-CG1 3.91Å; L219-V272 HydrophobicContact CD2-CB 4.23Å; L219-V272 HydrophobicContact CD2-CG2 3.57Å; L268-V272 PolarHBondContact O-N 3.29Å; L269-V272 WeakPolarHBondContact O-CA 3.43Å; L269-V272 WeakPolarHBondContact O-CB 3.25Å; L269-V272 PolarHBondContact O-N 3.23Å; L269-V272 VanDerWaalsContact O-N 3.08Å; M270-V272 VanDerWaalsContact C-N 3.3Å; M270-V272 PolarHBondContact O-N 3.38Å; V272-K275 PolarHBondContact O-N 3.16Å; V272-H276 PolarHBondContact O-N 3.32Å; V272-H276 PolarHBondContact O-ND1 2.94Å
273V94.8Very high93.3Very high0 Ų022.7 Ų22.70%013%0.127CC..Hα-helixtrans-63.3-41.4177.3173.10000111.3W25 L28 L29 M32 L269 M270 G277 S278 T281 R282W25-V273 HydrophobicContact CZ3-CG2 4.35Å; L28-V273 HydrophobicContact CD2-CG2 3.81Å; L29-V273 HydrophobicContact CD2-CG2 4.12Å; M32-V273 HydrophobicContact CE-CG2 3.79Å; M32-V273 HydrophobicContact SD-CG2 3.37Å; M32-V273 WeakPolarHBondContact SD-CG2 3.48Å; L269-V273 PolarHBondContact O-N 3.46Å; M270-V273 PolarHBondContact O-N 3.48Å; V273-G277 CarbonylContact O-C 3.24Å; V273-G277 VanDerWaalsContact O-C 3.24Å; V273-G277 WeakPolarHBondContact O-CA 3.15Å; V273-G277 PolarHBondContact O-N 2.72Å; V273-S278 PolarHBondContact O-N 3.42Å; V273-T281 HydrophobicContact CG1-CG2 4.11Å; V273-R282 HydrophobicContact CG1-CB 4.27Å
274L93.4Very high93.3Very high4 Ų421.5 Ų21.52%0.02112%0.122CC..Hα-helixtrans-70-39178-69.1172.8000111.8T208 E209 L212 K213 M270 S271T208-L274 HydrophobicContact CG2-CD1 3.8Å; E209-L274 HydrophobicContact CB-CD2 4.26Å; L212-L274 HydrophobicContact CD1-CB 3.85Å; K213-L274 WeakPolarHBondContact CE-O 3.2Å; M270-L274 WeakPolarHBondContact O-CB 3.48Å; M270-L274 WeakPolarHBondContact O-CG 3.47Å; M270-L274 PolarHBondContact O-N 3.41Å; S271-L274 PolarHBondContact O-N 3.08Å
275K93.7Very high93.3Very high36 Ų3621.6 Ų21.616%0.15712%0.122CC..Hα-helixtrans-67.7-46.8178.1-179.972.8174.3-1580112.3L212 K213 Q215 L219 S271 V272L212-K275 HydrophobicContact CB-CB 4.43Å; L212-K275 HydrophobicContact CB-CD 4Å; L212-K275 WeakPolarHBondContact O-CD 3.39Å; L212-K275 WeakPolarHBondContact O-CE 2.96Å; L212-K275 PolarHBondContact O-NZ 2.67Å; K213-K275 VanDerWaalsContact CE-O 3.32Å; K213-K275 WeakPolarHBondContact CE-O 3.36Å; Q215-K275 PolarHBondContact O-NZ 3.14Å; Q215-K275 VanDerWaalsContact O-NZ 3.1Å; L219-K275 HydrophobicContact CD1-CB 3.88Å; L219-K275 HydrophobicContact CD1-CD 4.38Å; L219-K275 HydrophobicContact CD1-CG 4.06Å; S271-K275 VanDerWaalsContact O-CB 3.25Å; S271-K275 WeakPolarHBondContact O-CB 3.28Å; S271-K275 PolarHBondContact O-N 2.96Å; V272-K275 PolarHBondContact O-N 3.16Å
276H91.5Very high93.1Very high118 Ų11820.9 Ų20.955%0.54611%0.113SC..Hα-helixtrans-109.2-14.7-169-56.395.3000114.7W25 V272W25-H276 HydrophobicContact CH2-CB 3.77Å; W25-H276 HydrophobicContact CZ2-CB 3.64Å; V272-H276 PolarHBondContact O-N 3.32Å; V272-H276 PolarHBondContact O-ND1 2.94Å
277G88.9Confident93.1Very high23 Ų2320.6 Ų20.624%0.23711%0.112CC..SBendtrans-113.1-123.6177.500000111K213 V273K213-G277 PolarHBondContact NZ-O 2.95Å; V273-G277 CarbonylContact O-C 3.24Å; V273-G277 VanDerWaalsContact O-C 3.24Å; V273-G277 WeakPolarHBondContact O-CA 3.15Å; V273-G277 PolarHBondContact O-N 2.72Å
278S90.8Very high93.1Very high11 Ų1121.8 Ų21.88%0.07712%0.118CC..  trans-151.1157.3177.663.10000111.2V273 I280 T281 R282V273-S278 PolarHBondContact O-N 3.42Å; S278-I280 PolarHBondContact O-N 3.02Å; S278-T281 WeakPolarHBondContact O-CB 3.49Å; S278-T281 PolarHBondContact O-N 3.3Å; S278-T281 PolarHBondContact OG-N 2.94Å; S278-T281 VanDerWaalsContact OG-N 3.09Å; S278-T281 PolarHBondContact OG-OG1 3.13Å; S278-R282 PolarHBondContact O-N 3.42Å
279G89.1Confident93Very high1 Ų120.7 Ų20.71%0.0111%0.112CC..Hα-helixtrans-57-29.5169.100000112.6E209 R282 L283E209-G279 WeakPolarHBondContact OE2-CA 2.97Å; E209-G279 PolarHBondContact OE2-N 3.32Å; G279-R282 WeakPolarHBondContact O-CB 3.41Å; G279-R282 PolarHBondContact O-N 2.9Å; G279-L283 PolarHBondContact O-N 3.21Å; G279-L283 VanDerWaalsContact O-N 3.16Å
280I91.7Very high92.8Very high0 Ų020.4 Ų20.40%011%0.111CC..Hα-helixtrans-67.6-41.2174.2-63.5170.6000111.7Y137 L145 L153 S278 R282 L283 F284 Y323Y137-I280 HydrophobicContact CD1-CD1 3.5Å; Y137-I280 VanDerWaalsContact CD1-CD1 3.5Å; Y137-I280 HydrophobicContact CD1-CG1 4.3Å; Y137-I280 HydrophobicContact CD2-CD1 4.44Å; Y137-I280 HydrophobicContact CD2-CG1 4.48Å; Y137-I280 HydrophobicContact CE1-CD1 3.52Å; Y137-I280 HydrophobicContact CE1-CG1 4.48Å; Y137-I280 HydrophobicContact CE2-CD1 4.49Å; Y137-I280 HydrophobicContact CG-CD1 3.98Å; Y137-I280 HydrophobicContact CG-CG1 4.29Å; L145-I280 HydrophobicContact CD1-CD1 4.43Å; L145-I280 HydrophobicContact CD2-CD1 3.73Å; L153-I280 HydrophobicContact CD1-CD1 4.35Å; L153-I280 HydrophobicContact CD2-CG2 3.79Å; S278-I280 PolarHBondContact O-N 3.02Å; I280-R282 PolarHBondContact O-N 3.18Å; I280-L283 WeakPolarHBondContact O-CA 3.3Å; I280-L283 WeakPolarHBondContact O-CB 3.43Å; I280-L283 PolarHBondContact O-N 2.93Å; I280-F284 HydrophobicContact CG2-CD2 3.98Å; I280-F284 HydrophobicContact CG2-CE2 3.84Å; I280-F284 WeakPolarHBondContact O-CD2 3.49Å; I280-F284 PolarHBondContact O-N 2.97Å; I280-F284 VanDerWaalsContact O-N 3.1Å; I280-Y323 HydrophobicContact CD1-CE2 4.03Å; I280-Y323 WeakPolarHBondContact CD1-OH 3.41Å; I280-Y323 HydrophobicContact CG2-CD2 4.28Å; I280-Y323 HydrophobicContact CG2-CE1 3.97Å; I280-Y323 HydrophobicContact CG2-CE2 3.62Å; I280-Y323 VanDerWaalsContact CG2-CZ 3.45Å
281T92.8Very high92.6Very high15 Ų1521.3 Ų21.39%0.09212%0.115CC..Hα-helixtrans-60.7-37175.5-53.90000110.6L29 V273 S278 L283 F284 V285 Y324L29-T281 HydrophobicContact CD1-CG2 4.43Å; L29-T281 HydrophobicContact CD2-CG2 3.9Å; V273-T281 HydrophobicContact CG1-CG2 4.11Å; S278-T281 WeakPolarHBondContact O-CB 3.49Å; S278-T281 PolarHBondContact O-N 3.3Å; S278-T281 PolarHBondContact OG-N 2.94Å; S278-T281 VanDerWaalsContact OG-N 3.09Å; S278-T281 PolarHBondContact OG-OG1 3.13Å; T281-L283 VanDerWaalsContact C-N 3.34Å; T281-L283 PolarHBondContact O-N 2.96Å; T281-F284 PolarHBondContact O-N 3.5Å; T281-V285 WeakPolarHBondContact O-CG2 3.39Å; T281-V285 PolarHBondContact O-N 3.06Å; T281-Y324 PolarHBondContact OG1-OH 3.43Å
282R93.3Very high92.5Very high44 Ų4422.3 Ų22.317%0.16612%0.121CC..Hα-helixtrans-59.7-40.8171.3157.6177.3178.6-169.61.6112.3Y103 M270 V273 S278 G279 I280 V285 I286Y103-R282 PolarHBondContact OH-NH1 3.5Å; M270-R282 HydrophobicContact CE-CG 4.16Å; M270-R282 HydrophobicContact SD-CB 3.98Å; M270-R282 HydrophobicContact SD-CG 3.55Å; M270-R282 VanDerWaalsContact SD-CG 3.55Å; V273-R282 HydrophobicContact CG1-CB 4.27Å; S278-R282 PolarHBondContact O-N 3.42Å; G279-R282 WeakPolarHBondContact O-CB 3.41Å; G279-R282 PolarHBondContact O-N 2.9Å; I280-R282 PolarHBondContact O-N 3.18Å; R282-V285 PolarHBondContact O-N 3.15Å; R282-I286 HydrophobicContact CG-CD1 3.89Å; R282-I286 VanDerWaalsContact O-CG1 3.32Å; R282-I286 WeakPolarHBondContact O-CG1 3.42Å; R282-I286 PolarHBondContact O-N 2.77Å
283L93.9Very high92.3Very high10 Ų1022.2 Ų22.25%0.05212%0.12CC..Hα-helixtrans-62.2-43.8176.2-62.6174.2000111.3I130 T133 L156 G279 I280 T281 V285 I286 S287I130-L283 HydrophobicContact CG1-CD2 4.29Å; I130-L283 HydrophobicContact CG2-CD1 4.22Å; T133-L283 HydrophobicContact CG2-CD1 3.96Å; T133-L283 HydrophobicContact CG2-CG 4.46Å; L156-L283 HydrophobicContact CD2-CB 4.21Å; G279-L283 PolarHBondContact O-N 3.21Å; G279-L283 VanDerWaalsContact O-N 3.16Å; I280-L283 WeakPolarHBondContact O-CA 3.3Å; I280-L283 WeakPolarHBondContact O-CB 3.43Å; I280-L283 PolarHBondContact O-N 2.93Å; T281-L283 VanDerWaalsContact C-N 3.34Å; T281-L283 PolarHBondContact O-N 2.96Å; L283-V285 PolarHBondContact O-N 3.34Å; L283-I286 PolarHBondContact O-N 3.4Å; L283-S287 PolarHBondContact O-N 3.22Å; L283-S287 PolarHBondContact O-OG 3.4Å
284F94.9Very high91.9Very high10 Ų1022.8 Ų22.84%0.04412%0.124CC..Hα-helixtrans-60.6-42.2174.7-82.1-73.4000112.7L156 I280 T281 I286 S287 C288 A319 A320 Y323 Y324L156-F284 HydrophobicContact CD1-CD1 3.79Å; L156-F284 HydrophobicContact CD1-CE1 3.77Å; L156-F284 HydrophobicContact CD2-CD1 3.96Å; L156-F284 HydrophobicContact CD2-CD2 4.38Å; L156-F284 HydrophobicContact CD2-CE1 3.94Å; L156-F284 HydrophobicContact CD2-CE2 4.37Å; L156-F284 HydrophobicContact CD2-CG 4.18Å; L156-F284 HydrophobicContact CD2-CZ 4.16Å; L156-F284 HydrophobicContact CG-CE1 4.37Å; I280-F284 HydrophobicContact CG2-CD2 3.98Å; I280-F284 HydrophobicContact CG2-CE2 3.84Å; I280-F284 WeakPolarHBondContact O-CD2 3.49Å; I280-F284 PolarHBondContact O-N 2.97Å; I280-F284 VanDerWaalsContact O-N 3.1Å; T281-F284 PolarHBondContact O-N 3.5Å; F284-I286 VanDerWaalsContact C-N 3.34Å; F284-I286 PolarHBondContact O-N 3.36Å; F284-S287 PolarHBondContact O-N 3.1Å; F284-C288 WeakPolarHBondContact O-CB 3.43Å; F284-C288 PolarHBondContact O-N 3.13Å; F284-C288 PolarHBondContact O-SG 3.17Å; F284-A319 HydrophobicContact CE1-CB 3.92Å; F284-A319 HydrophobicContact CZ-CB 4.39Å; F284-A320 HydrophobicContact CD1-CB 4.17Å; F284-A320 HydrophobicContact CE1-CB 3.96Å; F284-Y323 AromaticContact CE2-CD1 3.84Å; F284-Y323 HydrophobicContact CE2-CD1 3.84Å; F284-Y323 HydrophobicContact CE2-CD2 4.11Å; F284-Y323 HydrophobicContact CE2-CE1 4.47Å; F284-Y323 AromaticContact CE2-CG 3.65Å; F284-Y323 HydrophobicContact CE2-CG 3.65Å; F284-Y323 HydrophobicContact CZ-CD1 4.48Å; F284-Y323 HydrophobicContact CZ-CD2 4.48Å; F284-Y323 AromaticContact CZ-CG 3.96Å; F284-Y323 HydrophobicContact CZ-CG 3.96Å; F284-Y324 HydrophobicContact CD2-CE2 4.25Å; F284-Y324 HydrophobicContact CE2-CE2 4.37Å
285V95Very high91.7Very high5 Ų526.9 Ų26.93%0.0315%0.146CC..Hα-helixtrans-58.6-46.8174.5168.50000111.1L29 M32 V33 M270 T281 R282 L283 C288 S289L29-V285 HydrophobicContact CD2-CG2 3.56Å; M32-V285 HydrophobicContact CB-CG1 3.65Å; M32-V285 HydrophobicContact CE-CG1 4.32Å; V33-V285 HydrophobicContact CG2-CB 4.41Å; V33-V285 HydrophobicContact CG2-CG1 4.03Å; M270-V285 HydrophobicContact CE-CG1 4.01Å; T281-V285 WeakPolarHBondContact O-CG2 3.39Å; T281-V285 PolarHBondContact O-N 3.06Å; R282-V285 PolarHBondContact O-N 3.15Å; L283-V285 PolarHBondContact O-N 3.34Å; V285-C288 PolarHBondContact O-N 2.87Å; V285-S289 WeakPolarHBondContact O-CB 3.36Å; V285-S289 PolarHBondContact O-N 3.32Å
286I92.5Very high91.6Very high20 Ų2027.2 Ų27.210%0.10315%0.149CC..Hα-helixtrans-61.9-45.6178.1-66165.1000110.1Y36 M270 R282 L283 F284 S289Y36-I286 HydrophobicContact CE1-CG1 4.42Å; Y36-I286 HydrophobicContact CE1-CG2 4.04Å; Y36-I286 HydrophobicContact CE2-CG1 4.21Å; M270-I286 HydrophobicContact CE-CG1 4.08Å; R282-I286 HydrophobicContact CG-CD1 3.89Å; R282-I286 VanDerWaalsContact O-CG1 3.32Å; R282-I286 WeakPolarHBondContact O-CG1 3.42Å; R282-I286 PolarHBondContact O-N 2.77Å; L283-I286 PolarHBondContact O-N 3.4Å; F284-I286 VanDerWaalsContact C-N 3.34Å; F284-I286 PolarHBondContact O-N 3.36Å; I286-S289 WeakPolarHBondContact O-CB 3.12Å; I286-S289 PolarHBondContact O-N 3.26Å; I286-S289 PolarHBondContact O-OG 2.97Å
287S93.4Very high91.3Very high4 Ų422.3 Ų22.33%0.02813%0.128CC..Hα-helixtrans-64.8-44.6178.8-62.30000112.8L156 L283 F284 S289 M290 I316L156-S287 VanDerWaalsContact CD1-CB 3.49Å; L156-S287 WeakPolarHBondContact CD1-OG 3.5Å; L156-S287 WeakPolarHBondContact CG-OG 3.49Å; L283-S287 PolarHBondContact O-N 3.22Å; L283-S287 PolarHBondContact O-OG 3.4Å; F284-S287 PolarHBondContact O-N 3.1Å; S287-S289 PolarHBondContact O-N 3.05Å; S287-M290 VanDerWaalsContact O-CB 3.24Å; S287-M290 WeakPolarHBondContact O-CB 3.41Å; S287-M290 WeakPolarHBondContact O-CG 3.33Å; S287-M290 PolarHBondContact O-N 3.05Å; S287-M290 VanDerWaalsContact O-N 3.16Å; S287-I316 WeakPolarHBondContact O-CD1 3.34Å
288C93.9Very high91.2Very high38 Ų3827.9 Ų27.926%0.25714%0.142SC..Hα-helixtrans-62.4-32.7175.8-69.70000112.5V33 F284 V285 M290 L291 I316V33-C288 HydrophobicContact CG1-CB 4.01Å; V33-C288 HydrophobicContact CG2-CB 3.73Å; F284-C288 WeakPolarHBondContact O-CB 3.43Å; F284-C288 PolarHBondContact O-N 3.13Å; F284-C288 PolarHBondContact O-SG 3.17Å; V285-C288 PolarHBondContact O-N 2.87Å; C288-M290 PolarHBondContact O-N 3.43Å; C288-L291 VanDerWaalsContact O-CB 3.31Å; C288-L291 WeakPolarHBondContact O-CB 3.33Å; C288-L291 PolarHBondContact O-N 3.33Å; C288-L291 VanDerWaalsContact O-N 3.1Å; C288-I316 VanDerWaalsContact SG-CG2 3.52Å
289S93.2Very high91.1Very high4 Ų430.7 Ų30.73%0.02817%0.166CC..Hα-helixtrans-63.4-22.417880.70000113.5V33 Y36 G37 V285 I286 S287 L291 V292 N293V33-S289 WeakPolarHBondContact O-CB 3.36Å; Y36-S289 WeakPolarHBondContact CD1-OG 3.47Å; G37-S289 VanDerWaalsContact CA-O 3.23Å; G37-S289 WeakPolarHBondContact CA-O 3.38Å; V285-S289 WeakPolarHBondContact O-CB 3.36Å; V285-S289 PolarHBondContact O-N 3.32Å; I286-S289 WeakPolarHBondContact O-CB 3.12Å; I286-S289 PolarHBondContact O-N 3.26Å; I286-S289 PolarHBondContact O-OG 2.97Å; S287-S289 PolarHBondContact O-N 3.05Å; S289-L291 PolarHBondContact O-N 3.41Å; S289-V292 PolarHBondContact O-N 3.32Å; S289-N293 WeakPolarHBondContact O-CB 3.25Å; S289-N293 PolarHBondContact O-N 3.4Å
290M89.5Confident90.9Very high28 Ų2834.9 Ų34.914%0.13819%0.187CC..Hα-helixtrans-64.6-28.5176.2-57.1167.667.600111.3H163 S287 C288 A294H163-M290 HydrophobicContact CB-CE 3.44Å; H163-M290 VanDerWaalsContact CB-CE 3.44Å; H163-M290 WeakPolarHBondContact CD2-CE 3.31Å; H163-M290 PolarHBondContact CE1-O 3.19Å; S287-M290 VanDerWaalsContact O-CB 3.24Å; S287-M290 WeakPolarHBondContact O-CB 3.41Å; S287-M290 WeakPolarHBondContact O-CG 3.33Å; S287-M290 PolarHBondContact O-N 3.05Å; S287-M290 VanDerWaalsContact O-N 3.16Å; C288-M290 PolarHBondContact O-N 3.43Å; M290-A294 PolarHBondContact O-N 3.41Å; M290-A294 VanDerWaalsContact O-N 3.12Å
291L90.1Very high90.4Very high34 Ų3437.3 Ų37.318%0.17820%0.2CC..Hα-helixtrans-69.8-48.3174.5-55178.9000111.4C288 S289 N293 A294 L295 F309 T313 I316C288-L291 VanDerWaalsContact O-CB 3.31Å; C288-L291 WeakPolarHBondContact O-CB 3.33Å; C288-L291 PolarHBondContact O-N 3.33Å; C288-L291 VanDerWaalsContact O-N 3.1Å; S289-L291 PolarHBondContact O-N 3.41Å; L291-N293 VanDerWaalsContact C-N 3.3Å; L291-N293 PolarHBondContact O-N 2.88Å; L291-A294 PolarHBondContact O-N 3.16Å; L291-L295 WeakPolarHBondContact O-CG 3.38Å; L291-L295 PolarHBondContact O-N 3.36Å; L291-F309 HydrophobicContact CB-CZ 4.34Å; L291-F309 HydrophobicContact CD2-CE2 3.91Å; L291-F309 HydrophobicContact CD2-CZ 3.73Å; L291-T313 HydrophobicContact CD1-CG2 3.97Å; L291-T313 HydrophobicContact CD2-CG2 3.89Å; L291-T313 WeakPolarHBondContact CD2-OG1 3.44Å; L291-I316 HydrophobicContact CD2-CD1 4.27Å; L291-I316 HydrophobicContact CG-CD1 4.32Å
292V92.3Very high89.6Confident26 Ų2639.5 Ų39.516%0.15823%0.225CC..Hα-helixtrans-58.9-46175.3168.20000110V33 L34 S289 A294 L295 L296V33-V292 HydrophobicContact CG1-CG2 3.68Å; L34-V292 HydrophobicContact CD1-CG1 4Å; S289-V292 PolarHBondContact O-N 3.32Å; V292-A294 VanDerWaalsContact C-N 3.33Å; V292-A294 PolarHBondContact O-N 3.4Å; V292-L295 PolarHBondContact O-N 3.45Å; V292-L296 HydrophobicContact CB-CD1 4.46Å; V292-L296 HydrophobicContact CG1-CD1 3.24Å; V292-L296 WeakPolarHBondContact O-CB 3.45Å; V292-L296 WeakPolarHBondContact O-CD1 3.08Å; V292-L296 PolarHBondContact O-N 2.96Å
293N90Very high88.8Confident36 Ų3638 Ų3819%0.19322%0.221CC..Hα-helixtrans-53.6-48.8176.3175.750.3000112.1G37 P41 S289 L291 S297G37-N293 VanDerWaalsContact O-CA 3.24Å; G37-N293 WeakPolarHBondContact O-CA 3.11Å; G37-N293 WeakPolarHBondContact O-CB 3.32Å; P41-N293 WeakPolarHBondContact CD-OD1 3.36Å; P41-N293 WeakPolarHBondContact CG-OD1 3.44Å; S289-N293 WeakPolarHBondContact O-CB 3.25Å; S289-N293 PolarHBondContact O-N 3.4Å; L291-N293 VanDerWaalsContact C-N 3.3Å; L291-N293 PolarHBondContact O-N 2.88Å; N293-S297 WeakPolarHBondContact O-CB 3.33Å; N293-S297 PolarHBondContact O-N 3.5Å; N293-S297 PolarHBondContact O-OG 2.87Å
294A86.9Confident87.9Confident12 Ų1245.6 Ų45.610%0.09926%0.256CS..Hα-helixtrans-65.3-43.1179.600000112.7M290 L291 V292 S297 W298 L305 F309M290-A294 PolarHBondContact O-N 3.41Å; M290-A294 VanDerWaalsContact O-N 3.12Å; L291-A294 PolarHBondContact O-N 3.16Å; V292-A294 VanDerWaalsContact C-N 3.33Å; V292-A294 PolarHBondContact O-N 3.4Å; A294-S297 WeakPolarHBondContact O-CB 3.28Å; A294-S297 PolarHBondContact O-N 3.35Å; A294-W298 PolarHBondContact O-N 3.48Å; A294-L305 HydrophobicContact CB-CD2 4.12Å; A294-F309 HydrophobicContact CB-CD2 3.77Å; A294-F309 HydrophobicContact CB-CE2 3.19Å; A294-F309 HydrophobicContact CB-CZ 3.75Å
295L89.2Confident86.8Confident90 Ų9048.2 Ų48.247%0.47127%0.27SS..Hα-helixtrans-65-43.2178.8-69.4174.3000112.2L291 V292 W298 A299L291-L295 WeakPolarHBondContact O-CG 3.38Å; L291-L295 PolarHBondContact O-N 3.36Å; V292-L295 PolarHBondContact O-N 3.45Å; L295-W298 PolarHBondContact O-N 3.31Å; L295-A299 WeakPolarHBondContact O-CB 3.29Å; L295-A299 PolarHBondContact O-N 3.38Å
296L89.8Confident85.9Confident43 Ų4349.3 Ų49.323%0.22528%0.277CS..Hα-helixtrans-68.1-36.8175-86.7128.3000111.9P41 V292 A299 L300P41-L296 HydrophobicContact CB-CB 4.29Å; P41-L296 HydrophobicContact CG-CB 4.02Å; V292-L296 HydrophobicContact CB-CD1 4.46Å; V292-L296 HydrophobicContact CG1-CD1 3.24Å; V292-L296 WeakPolarHBondContact O-CB 3.45Å; V292-L296 WeakPolarHBondContact O-CD1 3.08Å; V292-L296 PolarHBondContact O-N 2.96Å; L296-A299 PolarHBondContact O-N 2.81Å; L296-L300 HydrophobicContact CB-CD1 4.42Å; L296-L300 HydrophobicContact CD2-CD1 3.6Å; L296-L300 HydrophobicContact CD2-CG 4.33Å; L296-L300 VanDerWaalsContact O-CB 3.23Å; L296-L300 WeakPolarHBondContact O-CB 3.45Å; L296-L300 WeakPolarHBondContact O-CG 3.42Å; L296-L300 PolarHBondContact O-N 3.05Å
297S86Confident84.9Confident14 Ų1453.6 Ų53.610%0.09831%0.306CS..Hα-helixtrans-61.5-43.6173.8-67.50000111.5N293 A294 L301 G302N293-S297 WeakPolarHBondContact O-CB 3.33Å; N293-S297 PolarHBondContact O-N 3.5Å; N293-S297 PolarHBondContact O-OG 2.87Å; A294-S297 WeakPolarHBondContact O-CB 3.28Å; A294-S297 PolarHBondContact O-N 3.35Å; S297-L301 WeakPolarHBondContact O-CA 3.38Å; S297-L301 WeakPolarHBondContact O-CB 3.32Å; S297-L301 PolarHBondContact O-N 2.5Å; S297-G302 PolarHBondContact O-N 3.38Å
298W87Confident84.2Confident141 Ų14159.9 Ų59.953%0.53433%0.333SS..Hα-helixtrans-63-48.8172.8169.774.7000112.1A294 L295 G302 L303 L305A294-W298 PolarHBondContact O-N 3.48Å; L295-W298 PolarHBondContact O-N 3.31Å; W298-G302 VanDerWaalsContact O-CA 3.25Å; W298-G302 WeakPolarHBondContact O-CA 3.37Å; W298-G302 PolarHBondContact O-N 3.22Å; W298-L303 WeakPolarHBondContact CA-O 3.47Å; W298-L305 HydrophobicContact CB-CD1 3.66Å; W298-L305 HydrophobicContact CB-CG 3.85Å; W298-L305 HydrophobicContact CD2-CD1 3.89Å; W298-L305 HydrophobicContact CE3-CD1 4.47Å; W298-L305 HydrophobicContact CG-CD1 3.49Å; W298-L305 VanDerWaalsContact CG-CD1 3.49Å; W298-L305 HydrophobicContact CG-CG 4.01Å
299A87.7Confident83.5Confident70 Ų7059.2 Ų59.258%0.57933%0.326SS*.Hα-helixtrans-71.6-39.2-174.300000114L295 L296L295-A299 WeakPolarHBondContact O-CB 3.29Å; L295-A299 PolarHBondContact O-N 3.38Å; L296-A299 PolarHBondContact O-N 2.81Å
300L85.8Confident83.2Confident88 Ų8864.9 Ų64.946%0.46136%0.355SS..Hα-helixtrans-94.5-34.2-174.7-62.1176.6000113.1L45 L296L45-L300 HydrophobicContact CD1-CD1 4.09Å; L296-L300 HydrophobicContact CB-CD1 4.42Å; L296-L300 HydrophobicContact CD2-CD1 3.6Å; L296-L300 HydrophobicContact CD2-CG 4.33Å; L296-L300 VanDerWaalsContact O-CB 3.23Å; L296-L300 WeakPolarHBondContact O-CB 3.45Å; L296-L300 WeakPolarHBondContact O-CG 3.42Å; L296-L300 PolarHBondContact O-N 3.05Å
301L82.1Confident83.2Confident52 Ų5267.7 Ų67.727%0.27237%0.37SS..Hα-helixtrans-107.5-4.9-174.4-49.6171.4000112.5T44 L45 S297 L303T44-L301 HydrophobicContact CG2-CD1 3.75Å; T44-L301 HydrophobicContact CG2-CD2 4.2Å; L45-L301 HydrophobicContact CD2-CD2 3.56Å; L45-L301 HydrophobicContact CG-CD2 4.04Å; S297-L301 WeakPolarHBondContact O-CA 3.38Å; S297-L301 WeakPolarHBondContact O-CB 3.32Å; S297-L301 PolarHBondContact O-N 2.5Å; L301-L303 HydrophobicContact CB-CD1 4.02Å; L301-L303 HydrophobicContact CB-CG 4.12Å; L301-L303 HydrophobicContact CD1-CD1 3.96Å; L301-L303 PolarHBondContact O-N 2.96Å
302G76Confident83.2Confident60 Ų6066.1 Ų66.162%0.61936%0.362SS*.  trans70.216.8179.500000114.5S297 W298S297-G302 PolarHBondContact O-N 3.38Å; W298-G302 VanDerWaalsContact O-CA 3.25Å; W298-G302 WeakPolarHBondContact O-CA 3.37Å; W298-G302 PolarHBondContact O-N 3.22Å
303L76Confident83.2Confident14 Ų1467 Ų677%0.07337%0.368CS..PPolyproline II helixtrans-68.4129.5-177.2-73.8163.5000111.4Y172 W298 L301 L305Y172-L303 HydrophobicContact CD1-CD2 4.28Å; Y172-L303 HydrophobicContact CD2-CD2 4.22Å; Y172-L303 HydrophobicContact CE1-CD2 4.11Å; Y172-L303 HydrophobicContact CE2-CD2 4.04Å; Y172-L303 HydrophobicContact CG-CD2 4.35Å; W298-L303 WeakPolarHBondContact CA-O 3.47Å; L301-L303 HydrophobicContact CB-CD1 4.02Å; L301-L303 HydrophobicContact CB-CG 4.12Å; L301-L303 HydrophobicContact CD1-CD1 3.96Å; L301-L303 PolarHBondContact O-N 2.96Å; L303-L305 PolarHBondContact O-N 2.79Å
304Q74.4Confident83.3Confident169 Ų16968.6 Ų68.679%0.7938%0.382SS*.PPolyproline II helixtrans-70.7118.6-179.2-65.2-170.3-4.900111.4L170 T306L170-Q304 WeakPolarHBondContact CD2-O 3.37Å; Q304-T306 PolarHBondContact O-N 2.98Å
305L72.8Confident83.7Confident64 Ų6469.9 Ų69.934%0.33539%0.386SS..PPolyproline II helixtrans-68.8117175.1-76.5155.3000109.9A294 W298 L303 F309A294-L305 HydrophobicContact CB-CD2 4.12Å; W298-L305 HydrophobicContact CB-CD1 3.66Å; W298-L305 HydrophobicContact CB-CG 3.85Å; W298-L305 HydrophobicContact CD2-CD1 3.89Å; W298-L305 HydrophobicContact CE3-CD1 4.47Å; W298-L305 HydrophobicContact CG-CD1 3.49Å; W298-L305 VanDerWaalsContact CG-CD1 3.49Å; W298-L305 HydrophobicContact CG-CG 4.01Å; L303-L305 PolarHBondContact O-N 2.79Å; L305-F309 HydrophobicContact CD2-CB 4.45Å; L305-F309 HydrophobicContact CD2-CD1 4.04Å; L305-F309 HydrophobicContact CD2-CD2 4.32Å; L305-F309 HydrophobicContact CD2-CE1 4.39Å; L305-F309 HydrophobicContact CD2-CG 3.99Å
306T75.4Confident84Confident29 Ų2965.9 Ų65.918%0.17837%0.365CS..PPolyproline II helixtrans-69.2147172.156.80000110.5S166 L170 Q304 F308 F309S166-T306 PolarHBondContact OG-OG1 3.32Å; L170-T306 HydrophobicContact CD2-CG2 4.19Å; Q304-T306 PolarHBondContact O-N 2.98Å; T306-F308 PolarHBondContact O-N 3.44Å; T306-F308 VanDerWaalsContact O-N 3.11Å; T306-F309 WeakPolarHBondContact O-CB 3.28Å; T306-F309 PolarHBondContact O-N 2.9Å
307P71.1Confident84.2Confident109 Ų10965.9 Ų65.971%0.70838%0.376SS*.G310 helixtrans-60.4-22.3175.822.5-31.9000112.8F309 L310P307-F309 PolarHBondContact O-N 3.4Å; P307-L310 PolarHBondContact O-N 3.02Å
308F78.6Confident84.7Confident136 Ų13669.4 Ų69.460%0.59639%0.393SS*.G310 helixtrans-62.7-17.3172.7-67.7-73000113.9T306 L310 L311 P312T306-F308 PolarHBondContact O-N 3.44Å; T306-F308 VanDerWaalsContact O-N 3.11Å; F308-L310 PolarHBondContact O-N 3.15Å; F308-L311 PolarHBondContact O-N 3.36Å; F308-P312 WeakPolarHBondContact O-CD 3.36Å
309F80.3Confident85.1Confident24 Ų2462.7 Ų62.711%0.10537%0.368CS..G310 helixtrans-61.1-29.1175175.7-106.1000113.9L291 A294 L305 T306 P307 L311 P312 T313L291-F309 HydrophobicContact CB-CZ 4.34Å; L291-F309 HydrophobicContact CD2-CE2 3.91Å; L291-F309 HydrophobicContact CD2-CZ 3.73Å; A294-F309 HydrophobicContact CB-CD2 3.77Å; A294-F309 HydrophobicContact CB-CE2 3.19Å; A294-F309 HydrophobicContact CB-CZ 3.75Å; L305-F309 HydrophobicContact CD2-CB 4.45Å; L305-F309 HydrophobicContact CD2-CD1 4.04Å; L305-F309 HydrophobicContact CD2-CD2 4.32Å; L305-F309 HydrophobicContact CD2-CE1 4.39Å; L305-F309 HydrophobicContact CD2-CG 3.99Å; T306-F309 WeakPolarHBondContact O-CB 3.28Å; T306-F309 PolarHBondContact O-N 2.9Å; P307-F309 PolarHBondContact O-N 3.4Å; F309-L311 VanDerWaalsContact C-N 3.25Å; F309-L311 PolarHBondContact O-N 2.98Å; F309-P312 WeakPolarHBondContact O-CD 3.36Å; F309-T313 PolarHBondContact O-N 3.44Å; F309-T313 PolarHBondContact O-OG1 3.42Å
310L85.4Confident85.4Confident123 Ų12360.8 Ų60.864%0.64435%0.352SS*.Hα-helixtrans-67.6-27.5178.7-65.1177000112.4P307 F308 T313 S314P307-L310 PolarHBondContact O-N 3.02Å; F308-L310 PolarHBondContact O-N 3.15Å; L310-T313 PolarHBondContact O-N 3.38Å; L310-S314 PolarHBondContact O-N 3.11Å; L310-S314 PolarHBondContact O-OG 3.41Å
311L90.5Very high85.8Confident87 Ų8763.8 Ų63.846%0.45536%0.358SS..Hα-helixtrans-66.8-57.6-178.9177.172.8000111.7F308 F309 T313 S314 M315F308-L311 PolarHBondContact O-N 3.36Å; F309-L311 VanDerWaalsContact C-N 3.25Å; F309-L311 PolarHBondContact O-N 2.98Å; L311-T313 PolarHBondContact O-N 3.49Å; L311-S314 PolarHBondContact O-N 2.89Å; L311-S314 PolarHBondContact O-OG 3.03Å; L311-M315 HydrophobicContact CD1-CG 4.45Å; L311-M315 HydrophobicContact CD1-SD 4.28Å; L311-M315 HydrophobicContact CG-SD 4.06Å; L311-M315 VanDerWaalsContact O-CG 3.3Å; L311-M315 WeakPolarHBondContact O-CG 3.49Å; L311-M315 PolarHBondContact O-N 3.26Å
312P91.1Very high86.4Confident1 Ų163 Ų631%0.00635%0.354CS..Hα-helixtrans-53.7-38.4173-25.632.1000113.4C162 H163 F308 F309 M315 I316C162-P312 HydrophobicContact CB-CG 3.82Å; H163-P312 HydrophobicContact CB-CB 4.01Å; H163-P312 HydrophobicContact CB-CG 3.96Å; F308-P312 WeakPolarHBondContact O-CD 3.36Å; F309-P312 WeakPolarHBondContact O-CD 3.36Å; P312-M315 PolarHBondContact O-N 3.38Å; P312-I316 WeakPolarHBondContact O-CD1 3.4Å; P312-I316 VanDerWaalsContact O-CG1 3.23Å; P312-I316 WeakPolarHBondContact O-CG1 3.32Å; P312-I316 PolarHBondContact O-N 2.95Å
313T90.6Very high87.2Confident45 Ų4561 Ų6128%0.27633%0.328SS..Hα-helixtrans-60.7-50.3178.8-52.90000111.9L291 F309 L310 L311 M315 I316 G317L291-T313 HydrophobicContact CD1-CG2 3.97Å; L291-T313 HydrophobicContact CD2-CG2 3.89Å; L291-T313 WeakPolarHBondContact CD2-OG1 3.44Å; F309-T313 PolarHBondContact O-N 3.44Å; F309-T313 PolarHBondContact O-OG1 3.42Å; L310-T313 PolarHBondContact O-N 3.38Å; L311-T313 PolarHBondContact O-N 3.49Å; T313-M315 VanDerWaalsContact C-N 3.34Å; T313-M315 PolarHBondContact O-N 3.21Å; T313-I316 PolarHBondContact O-N 3.49Å; T313-G317 PolarHBondContact O-N 3.38Å; T313-G317 VanDerWaalsContact O-N 3.14Å
314S93.1Very high87.8Confident70 Ų7066.5 Ų66.549%0.4935%0.348SS..Hα-helixtrans-64.8-39.3177.965.90000111.9L310 L311 G317 L318L310-S314 PolarHBondContact O-N 3.11Å; L310-S314 PolarHBondContact O-OG 3.41Å; L311-S314 PolarHBondContact O-N 2.89Å; L311-S314 PolarHBondContact O-OG 3.03Å; S314-G317 PolarHBondContact O-N 3.44Å; S314-L318 WeakPolarHBondContact O-CB 3.35Å; S314-L318 PolarHBondContact O-N 3.2Å
315M95.6Very high88.3Confident39 Ų3965.3 Ų65.319%0.19235%0.347CS..Hα-helixtrans-63.1-42.9176.8-68.5176.377.600112.4I155 A159 L311 P312 T313 G317 L318 A319I155-M315 HydrophobicContact CG2-CB 3.86Å; I155-M315 HydrophobicContact CG2-CE 4.25Å; I155-M315 HydrophobicContact CG2-CG 4.4Å; I155-M315 VanDerWaalsContact CG2-O 3.28Å; I155-M315 WeakPolarHBondContact CG2-O 3.2Å; A159-M315 HydrophobicContact CB-CB 3.65Å; A159-M315 HydrophobicContact CB-SD 4.4Å; L311-M315 HydrophobicContact CD1-CG 4.45Å; L311-M315 HydrophobicContact CD1-SD 4.28Å; L311-M315 HydrophobicContact CG-SD 4.06Å; L311-M315 VanDerWaalsContact O-CG 3.3Å; L311-M315 WeakPolarHBondContact O-CG 3.49Å; L311-M315 PolarHBondContact O-N 3.26Å; P312-M315 PolarHBondContact O-N 3.38Å; T313-M315 VanDerWaalsContact C-N 3.34Å; T313-M315 PolarHBondContact O-N 3.21Å; M315-G317 VanDerWaalsContact C-N 3.35Å; M315-L318 PolarHBondContact O-N 2.84Å; M315-A319 VanDerWaalsContact O-CB 3.28Å; M315-A319 WeakPolarHBondContact O-CB 3.38Å; M315-A319 PolarHBondContact O-N 2.72Å
316I95.3Very high89.1Confident5 Ų565.4 Ų65.43%0.02635%0.347CS..Hα-helixtrans-62-44.2175.9-68.4161.1000110.5L156 A159 S287 C288 L291 P312 T313 A319 A320L156-I316 HydrophobicContact CD1-CG1 4.28Å; L156-I316 HydrophobicContact CD1-CG2 4.48Å; A159-I316 HydrophobicContact CB-CD1 4.48Å; A159-I316 HydrophobicContact CB-CG1 3.77Å; S287-I316 WeakPolarHBondContact O-CD1 3.34Å; C288-I316 VanDerWaalsContact SG-CG2 3.52Å; L291-I316 HydrophobicContact CD2-CD1 4.27Å; L291-I316 HydrophobicContact CG-CD1 4.32Å; P312-I316 WeakPolarHBondContact O-CD1 3.4Å; P312-I316 VanDerWaalsContact O-CG1 3.23Å; P312-I316 WeakPolarHBondContact O-CG1 3.32Å; P312-I316 PolarHBondContact O-N 2.95Å; T313-I316 PolarHBondContact O-N 3.49Å; I316-A319 PolarHBondContact O-N 2.96Å; I316-A320 WeakPolarHBondContact O-CB 3.36Å; I316-A320 PolarHBondContact O-N 2.87Å
317G93.8Very high89.8Confident44 Ų4467.3 Ų67.345%0.45436%0.356SS..Hα-helixtrans-60.5-46.3176.600000112.6T313 S314 M315 A320 Y321T313-G317 PolarHBondContact O-N 3.38Å; T313-G317 VanDerWaalsContact O-N 3.14Å; S314-G317 PolarHBondContact O-N 3.44Å; M315-G317 VanDerWaalsContact C-N 3.35Å; G317-A320 PolarHBondContact O-N 2.71Å; G317-Y321 WeakPolarHBondContact O-CB 3.36Å; G317-Y321 PolarHBondContact O-N 3.5Å
318L95.9Very high90.8Very high88 Ų8864.9 Ų64.946%0.46134%0.337SS..Hα-helixtrans-63.5-44.2176.7-179.961.4000111.9I155 S314 M315 A320 Y321 L322I155-L318 HydrophobicContact CD1-CD2 4.11Å; I155-L318 HydrophobicContact CD1-CG 4.33Å; S314-L318 WeakPolarHBondContact O-CB 3.35Å; S314-L318 PolarHBondContact O-N 3.2Å; M315-L318 PolarHBondContact O-N 2.84Å; L318-A320 VanDerWaalsContact C-N 3.35Å; L318-A320 PolarHBondContact O-N 2.63Å; L318-Y321 PolarHBondContact O-N 3.38Å; L318-L322 HydrophobicContact CD1-CD1 4.06Å; L318-L322 HydrophobicContact CD1-CG 4.14Å; L318-L322 HydrophobicContact CG-CD1 3.97Å; L318-L322 HydrophobicContact CG-CG 4.45Å; L318-L322 WeakPolarHBondContact O-CB 3.39Å; L318-L322 WeakPolarHBondContact O-CG 3.45Å; L318-L322 PolarHBondContact O-N 3.22Å
319A96.2Very high91.5Very high0 Ų060.8 Ų60.80%032%0.321CS..Hα-helixtrans-60.5-44.1176.300000111.6A152 I155 L156 F284 M315 I316 L322 Y323A152-A319 WeakPolarHBondContact CB-O 3.46Å; A152-A319 VanDerWaalsContact O-CB 3.28Å; A152-A319 WeakPolarHBondContact O-CB 3.32Å; I155-A319 HydrophobicContact CB-CB 4.16Å; I155-A319 HydrophobicContact CG2-CB 3.99Å; L156-A319 HydrophobicContact CB-CB 4.11Å; L156-A319 HydrophobicContact CD1-CB 4.23Å; F284-A319 HydrophobicContact CE1-CB 3.92Å; F284-A319 HydrophobicContact CZ-CB 4.39Å; M315-A319 VanDerWaalsContact O-CB 3.28Å; M315-A319 WeakPolarHBondContact O-CB 3.38Å; M315-A319 PolarHBondContact O-N 2.72Å; I316-A319 PolarHBondContact O-N 2.96Å; A319-L322 PolarHBondContact O-N 3.11Å; A319-Y323 VanDerWaalsContact O-CB 3.3Å; A319-Y323 WeakPolarHBondContact O-CB 3.36Å; A319-Y323 PolarHBondContact O-N 3.4Å
320A93.8Very high92.2Very high30 Ų3063.1 Ų63.125%0.24834%0.335CS..Hα-helixtrans-63.9-44.2177.900000111.1F284 I316 G317 L318 Y323 Y324F284-A320 HydrophobicContact CD1-CB 4.17Å; F284-A320 HydrophobicContact CE1-CB 3.96Å; I316-A320 WeakPolarHBondContact O-CB 3.36Å; I316-A320 PolarHBondContact O-N 2.87Å; G317-A320 PolarHBondContact O-N 2.71Å; L318-A320 VanDerWaalsContact C-N 3.35Å; L318-A320 PolarHBondContact O-N 2.63Å; A320-Y323 PolarHBondContact O-N 3.22Å; A320-Y324 VanDerWaalsContact O-CD2 3.29Å; A320-Y324 WeakPolarHBondContact O-CD2 3.25Å; A320-Y324 PolarHBondContact O-N 2.91Å
321Y93.8Very high92.7Very high150 Ų15059.1 Ų59.159%0.58831%0.314SS*.Hα-helixtrans-58.9-51.3175.8178.2-102.8000111.8G317 L318 Y323 Y324 L325G317-Y321 WeakPolarHBondContact O-CB 3.36Å; G317-Y321 PolarHBondContact O-N 3.5Å; L318-Y321 PolarHBondContact O-N 3.38Å; Y321-Y323 VanDerWaalsContact C-N 3.31Å; Y321-Y323 PolarHBondContact O-N 3.08Å; Y321-Y324 PolarHBondContact O-N 3.21Å; Y321-L325 HydrophobicContact CE2-CD1 4.31Å; Y321-L325 WeakPolarHBondContact O-CB 3.46Å; Y321-L325 PolarHBondContact O-N 3.22Å; Y321-L325 VanDerWaalsContact O-N 3.14Å
322L94.1Very high92.8Very high37 Ų3757.1 Ų57.119%0.19430%0.304CS..Hα-helixtrans-64.3-33-179.2-73173.1000113.4L151 A152 I155 L318 A319L151-L322 HydrophobicContact CD2-CD1 4.32Å; L151-L322 HydrophobicContact CG-CD1 4.5Å; A152-L322 HydrophobicContact CB-CB 3.91Å; I155-L322 HydrophobicContact CD1-CD1 3.61Å; L318-L322 HydrophobicContact CD1-CD1 4.06Å; L318-L322 HydrophobicContact CD1-CG 4.14Å; L318-L322 HydrophobicContact CG-CD1 3.97Å; L318-L322 HydrophobicContact CG-CG 4.45Å; L318-L322 WeakPolarHBondContact O-CB 3.39Å; L318-L322 WeakPolarHBondContact O-CG 3.45Å; L318-L322 PolarHBondContact O-N 3.22Å; A319-L322 PolarHBondContact O-N 3.11Å
323Y93.4Very high93Very high18 Ų1861.4 Ų61.47%0.07133%0.327CS..Hα-helixtrans-76.1-36.9-177.9-174.7-90.6000113.2L145 Q149 A152 I280 F284 A319 A320 Y321L145-Y323 HydrophobicContact CD2-CE2 4.32Å; Q149-Y323 HydrophobicContact CB-CD2 3.75Å; Q149-Y323 HydrophobicContact CB-CE2 3.82Å; Q149-Y323 HydrophobicContact CG-CD2 3.75Å; Q149-Y323 HydrophobicContact CG-CE2 3.87Å; Q149-Y323 HydrophobicContact CG-CG 4.41Å; A152-Y323 HydrophobicContact CB-CD2 4.4Å; I280-Y323 HydrophobicContact CD1-CE2 4.03Å; I280-Y323 WeakPolarHBondContact CD1-OH 3.41Å; I280-Y323 HydrophobicContact CG2-CD2 4.28Å; I280-Y323 HydrophobicContact CG2-CE1 3.97Å; I280-Y323 HydrophobicContact CG2-CE2 3.62Å; I280-Y323 VanDerWaalsContact CG2-CZ 3.45Å; F284-Y323 AromaticContact CE2-CD1 3.84Å; F284-Y323 HydrophobicContact CE2-CD1 3.84Å; F284-Y323 HydrophobicContact CE2-CD2 4.11Å; F284-Y323 HydrophobicContact CE2-CE1 4.47Å; F284-Y323 AromaticContact CE2-CG 3.65Å; F284-Y323 HydrophobicContact CE2-CG 3.65Å; F284-Y323 HydrophobicContact CZ-CD1 4.48Å; F284-Y323 HydrophobicContact CZ-CD2 4.48Å; F284-Y323 AromaticContact CZ-CG 3.96Å; F284-Y323 HydrophobicContact CZ-CG 3.96Å; A319-Y323 VanDerWaalsContact O-CB 3.3Å; A319-Y323 WeakPolarHBondContact O-CB 3.36Å; A319-Y323 PolarHBondContact O-N 3.4Å; A320-Y323 PolarHBondContact O-N 3.22Å; Y321-Y323 VanDerWaalsContact C-N 3.31Å; Y321-Y323 PolarHBondContact O-N 3.08Å
324Y88.7Confident93.2Very high128 Ų12862.8 Ų62.850%0.50233%0.331SS..Hα-helixtrans-98.94.8-175.7-67.7-70.5000114.2T281 F284 A320 Y321T281-Y324 PolarHBondContact OG1-OH 3.43Å; F284-Y324 HydrophobicContact CD2-CE2 4.25Å; F284-Y324 HydrophobicContact CE2-CE2 4.37Å; A320-Y324 VanDerWaalsContact O-CD2 3.29Å; A320-Y324 WeakPolarHBondContact O-CD2 3.25Å; A320-Y324 PolarHBondContact O-N 2.91Å; Y321-Y324 PolarHBondContact O-N 3.21Å
325L84.6Confident93.2Very high144 Ų14462.1 Ų62.175%0.75432%0.317SS*.  trans-70.50167.7-166.573.6000111.6Y321Y321-L325 HydrophobicContact CE2-CD1 4.31Å; Y321-L325 WeakPolarHBondContact O-CB 3.46Å; Y321-L325 PolarHBondContact O-N 3.22Å; Y321-L325 VanDerWaalsContact O-N 3.14Å

Retrieved 325 of 325 residues in 990.2 ms (Link to these results)

U.S. Privacy Notice - Disclaimer / Registrations / Copyright Statement - Linking Policy - Notice of Privacy Practices (HIPAA) - Notice of Non‑Discrimination
© Copyright 2026 St. Jude Children's Research Hospital, a not-for-profit, section 501(c)(3).