A0A060WZT8_ONCMY Loading...

Methyltransferase like 25B

AlphaFold DB , UniProt , Accession A0A060WZT8, Species ONCMY (Oncorhynchus mykiss, Rainbow trout), Gene mettl25b, Length 617 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M40.2Very low65.3Low150 Ų15098.3 Ų98.374%0.73955%0.553SS**  0146.10-64.7173.1-179.500108.2L148M1-L148 HydrophobicContact CE-CD1 3.84Å
2M29.4Very low67.8Low185 Ų18590.9 Ų90.991%0.91151%0.511SS*.PPolyproline II helixtrans-76.4126.5156.2-75.9-177.1170.700107.2S4M2-S4 PolarHBondContact O-N 3.13Å
3C36.8Very low70Confident103 Ų10390.3 Ų90.370%0.69650%0.496SS*.PPolyproline II helixtrans-67.1120.4179.6-62.60000109.8
4S42.3Very low72Confident58 Ų5889.3 Ų89.341%0.40649%0.486SS..PPolyproline II helixtrans-53.3138.6152.51770000107.7M2 T6M2-S4 PolarHBondContact O-N 3.13Å; S4-T6 PolarHBondContact O-N 3.49Å
5P49.5Very low73.7Confident121 Ų12185.1 Ų85.179%0.78646%0.463SS*.PPolyproline II helixtrans-55.6116.4179.422.2-33.2000109.6
6T69.8Low75.3Confident76 Ų7679.8 Ų79.847%0.46643%0.434SS..PPolyproline II helixtrans-69.6143.516743.30000108.3S4 S8 Q584S4-T6 PolarHBondContact O-N 3.49Å; T6-S8 PolarHBondContact O-N 3.19Å; T6-Q584 HydrophobicContact CG2-CB 4.2Å; T6-Q584 HydrophobicContact CG2-CG 4.13Å
7L83.9Confident76.7Confident62 Ų6282.6 Ų82.633%0.32544%0.437SS..PPolyproline II helixtrans-56.8134.2176.7-64.8179000109.6Q11 Q12 L15 F96L7-Q11 HydrophobicContact CB-CB 3.95Å; L7-Q11 HydrophobicContact CD2-CB 4.22Å; L7-Q12 HydrophobicContact CB-CG 3.7Å; L7-Q12 PolarHBondContact O-NE2 2.86Å; L7-L15 HydrophobicContact CD1-CD2 3.68Å; L7-F96 HydrophobicContact CD1-CE1 4.09Å
8S89.8Confident77.9Confident49 Ų4981.1 Ų81.134%0.34343%0.429SS..PPolyproline II helixtrans-59.6161.5174.4830000110.9T6 E10 Q11 Q12T6-S8 PolarHBondContact O-N 3.19Å; S8-E10 PolarHBondContact O-N 3.23Å; S8-E10 VanDerWaalsContact O-N 3.11Å; S8-E10 PolarHBondContact OG-N 3.48Å; S8-Q11 PolarHBondContact O-N 3.06Å; S8-Q11 WeakPolarHBondContact OG-CG 3.44Å; S8-Q11 PolarHBondContact OG-N 3.4Å; S8-Q11 VanDerWaalsContact OG-N 3.12Å; S8-Q12 WeakPolarHBondContact O-CG 3.31Å; S8-Q12 PolarHBondContact O-N 2.89Å
9A88.9Confident79Confident34 Ų3476.8 Ų76.828%0.28141%0.406SS..Hα-helixtrans-55-32.8177.400000112.8R13 Q577A9-R13 VanDerWaalsContact O-CG 3.31Å; A9-R13 WeakPolarHBondContact O-CG 3.42Å; A9-R13 PolarHBondContact O-N 2.94Å; A9-R13 VanDerWaalsContact O-N 3.17Å; A9-R13 PolarHBondContact O-NE 2.78Å; A9-Q577 VanDerWaalsContact CA-OE1 3.24Å; A9-Q577 VanDerWaalsContact CB-OE1 3.31Å
10E92.9Very high79.9Confident138 Ų13873.1 Ų73.165%0.64539%0.387SS*.Hα-helixtrans-75.2-45176.1-67.2154.8-177.700111.6S8 Q12 R13 E14S8-E10 PolarHBondContact O-N 3.23Å; S8-E10 VanDerWaalsContact O-N 3.11Å; S8-E10 PolarHBondContact OG-N 3.48Å; E10-Q12 VanDerWaalsContact C-N 3.28Å; E10-Q12 PolarHBondContact O-N 3.17Å; E10-R13 PolarHBondContact O-N 3.12Å; E10-E14 VanDerWaalsContact O-CB 3.25Å; E10-E14 WeakPolarHBondContact O-CB 3.45Å; E10-E14 PolarHBondContact O-N 3Å
11Q94.7Very high80.8Confident105 Ų10577.5 Ų77.549%0.49140%0.399SS..Hα-helixtrans-61.9-35.6175.6-71171.2-22.300112.2L7 S8 L15L7-Q11 HydrophobicContact CB-CB 3.95Å; L7-Q11 HydrophobicContact CD2-CB 4.22Å; S8-Q11 PolarHBondContact O-N 3.06Å; S8-Q11 WeakPolarHBondContact OG-CG 3.44Å; S8-Q11 PolarHBondContact OG-N 3.4Å; S8-Q11 VanDerWaalsContact OG-N 3.12Å; Q11-L15 WeakPolarHBondContact O-CB 3.2Å; Q11-L15 PolarHBondContact O-N 3.09Å
12Q95.1Very high83.6Confident10 Ų1070.9 Ų70.95%0.04737%0.366CS..Hα-helixtrans-66.3-47.9173-71.5-178.949.100111.7L7 S8 E10 E14 L15 A16 L570 L574L7-Q12 HydrophobicContact CB-CG 3.7Å; L7-Q12 PolarHBondContact O-NE2 2.86Å; S8-Q12 WeakPolarHBondContact O-CG 3.31Å; S8-Q12 PolarHBondContact O-N 2.89Å; E10-Q12 VanDerWaalsContact C-N 3.28Å; E10-Q12 PolarHBondContact O-N 3.17Å; Q12-E14 VanDerWaalsContact C-N 3.33Å; Q12-E14 PolarHBondContact O-N 3.12Å; Q12-L15 PolarHBondContact O-N 3.39Å; Q12-A16 PolarHBondContact O-N 3.11Å; Q12-L570 HydrophobicContact CB-CD1 3.84Å; Q12-L570 HydrophobicContact CG-CD1 4.01Å; Q12-L574 HydrophobicContact CB-CD2 3.81Å; Q12-L574 HydrophobicContact CB-CG 4.45Å
13R97.1Very high86.9Confident83 Ų8362.5 Ų62.531%0.31333%0.325SS..Hα-helixtrans-61.4-40.5177-77.9-171.5-65.3-110.53.6112.6A9 E10 A16 R17 W445 L574A9-R13 VanDerWaalsContact O-CG 3.31Å; A9-R13 WeakPolarHBondContact O-CG 3.42Å; A9-R13 PolarHBondContact O-N 2.94Å; A9-R13 VanDerWaalsContact O-N 3.17Å; A9-R13 PolarHBondContact O-NE 2.78Å; E10-R13 PolarHBondContact O-N 3.12Å; R13-A16 PolarHBondContact O-N 3.37Å; R13-R17 PolarHBondContact O-N 2.97Å; R13-R17 VanDerWaalsContact O-N 3.09Å; R13-W445 HydrophobicContact CB-CD2 4.18Å; R13-W445 HydrophobicContact CB-CH2 4.44Å; R13-W445 HydrophobicContact CB-CZ2 3.69Å; R13-W445 HydrophobicContact CG-CD2 3.63Å; R13-W445 HydrophobicContact CG-CE3 4.17Å; R13-W445 HydrophobicContact CG-CG 3.9Å; R13-W445 HydrophobicContact CG-CZ2 4.02Å; R13-W445 PolarHBondContact O-NE1 3.24Å; R13-W445 VanDerWaalsContact O-NE1 3.15Å; R13-L574 HydrophobicContact CG-CD2 4.07Å
14E97.9Very high89.8Confident76 Ų7660 Ų6036%0.35531%0.309SS..Hα-helixtrans-70.7-40.617817856.8-165.300112.2E10 Q12 A16 R17 N18E10-E14 VanDerWaalsContact O-CB 3.25Å; E10-E14 WeakPolarHBondContact O-CB 3.45Å; E10-E14 PolarHBondContact O-N 3Å; Q12-E14 VanDerWaalsContact C-N 3.33Å; Q12-E14 PolarHBondContact O-N 3.12Å; E14-A16 VanDerWaalsContact C-N 3.3Å; E14-A16 PolarHBondContact O-N 3.23Å; E14-R17 PolarHBondContact O-N 3.18Å; E14-R17 IonicContact OE1-CZ 3.63Å; E14-R17 IonicContact OE1-NE 3.76Å; E14-R17 IonicContact OE1-NH2 2.73Å; E14-R17 PolarHBondContact OE1-NH2 2.84Å; E14-R17 IonicContact OE2-CZ 3.25Å; E14-R17 VanDerWaalsContact OE2-CZ 3.25Å; E14-R17 IonicContact OE2-NE 2.75Å; E14-R17 PolarHBondContact OE2-NE 2.77Å; E14-R17 IonicContact OE2-NH2 2.92Å; E14-R17 PolarHBondContact OE2-NH2 3.45Å; E14-N18 VanDerWaalsContact CD-ND2 3.3Å; E14-N18 PolarHBondContact O-N 3.15Å; E14-N18 PolarHBondContact O-ND2 3.23Å; E14-N18 PolarHBondContact OE1-ND2 3.21Å
15L98Very high92.4Very high26 Ų2660.2 Ų60.214%0.13631%0.308CS..Hα-helixtrans-60.5-42.1172.7-179.260000110.9L7 Q11 Q12 R17 N18 L19 L94 F96 L570L7-L15 HydrophobicContact CD1-CD2 3.68Å; Q11-L15 WeakPolarHBondContact O-CB 3.2Å; Q11-L15 PolarHBondContact O-N 3.09Å; Q12-L15 PolarHBondContact O-N 3.39Å; L15-R17 PolarHBondContact O-N 2.92Å; L15-N18 PolarHBondContact O-N 3.44Å; L15-L19 HydrophobicContact CD1-CD1 4.23Å; L15-L19 HydrophobicContact CD1-CG 4.29Å; L15-L19 HydrophobicContact CG-CD1 3.88Å; L15-L19 HydrophobicContact CG-CG 4.41Å; L15-L19 WeakPolarHBondContact O-CB 3.37Å; L15-L19 WeakPolarHBondContact O-CD1 3.25Å; L15-L19 WeakPolarHBondContact O-CG 3.46Å; L15-L19 PolarHBondContact O-N 3.38Å; L15-L94 HydrophobicContact CD1-CB 4.37Å; L15-L94 HydrophobicContact CD1-CD2 3.91Å; L15-F96 HydrophobicContact CD2-CE1 4.17Å; L15-F96 HydrophobicContact CD2-CZ 4.24Å; L15-L570 HydrophobicContact CB-CD2 3.93Å; L15-L570 HydrophobicContact CD2-CD2 3.99Å; L15-L570 HydrophobicContact CG-CD2 3.77Å
16A98.4Very high94.8Very high0 Ų056.3 Ų56.30%028%0.278CS..Hα-helixtrans-60.9-45.517600000111.9Q12 R13 E14 N18 L19 T20 V446 L449 L570 L574Q12-A16 PolarHBondContact O-N 3.11Å; R13-A16 PolarHBondContact O-N 3.37Å; E14-A16 VanDerWaalsContact C-N 3.3Å; E14-A16 PolarHBondContact O-N 3.23Å; A16-N18 VanDerWaalsContact C-N 3.34Å; A16-N18 PolarHBondContact O-N 3.09Å; A16-L19 PolarHBondContact O-N 2.98Å; A16-T20 PolarHBondContact O-N 3.16Å; A16-V446 HydrophobicContact CB-CG2 4.18Å; A16-L449 HydrophobicContact CB-CD1 3.77Å; A16-L570 HydrophobicContact CB-CD2 3.71Å; A16-L570 HydrophobicContact CB-CG 4.39Å; A16-L574 HydrophobicContact CB-CD1 4.01Å
17R98.6Very high96.1Very high128 Ų12857 Ų5748%0.48327%0.274SS..Hα-helixtrans-58.3-43.5176.7-172.8176.573.5102.80.7112.3R13 E14 L15 T20 Y21 L449R13-R17 PolarHBondContact O-N 2.97Å; R13-R17 VanDerWaalsContact O-N 3.09Å; E14-R17 PolarHBondContact O-N 3.18Å; E14-R17 IonicContact OE1-CZ 3.63Å; E14-R17 IonicContact OE1-NE 3.76Å; E14-R17 IonicContact OE1-NH2 2.73Å; E14-R17 PolarHBondContact OE1-NH2 2.84Å; E14-R17 IonicContact OE2-CZ 3.25Å; E14-R17 VanDerWaalsContact OE2-CZ 3.25Å; E14-R17 IonicContact OE2-NE 2.75Å; E14-R17 PolarHBondContact OE2-NE 2.77Å; E14-R17 IonicContact OE2-NH2 2.92Å; E14-R17 PolarHBondContact OE2-NH2 3.45Å; L15-R17 PolarHBondContact O-N 2.92Å; R17-T20 PolarHBondContact O-OG1 2.73Å; R17-Y21 WeakPolarHBondContact O-CB 3.29Å; R17-Y21 PolarHBondContact O-N 2.75Å; R17-L449 HydrophobicContact CB-CD2 4.22Å; R17-L449 HydrophobicContact CG-CD2 4.34Å
18N98.6Very high96.7Very high55 Ų5557.9 Ų57.929%0.29428%0.276SS..Hα-helixtrans-72.4-34178.4-70.5-61.4000112.6E14 L15 A16 F22 L94E14-N18 VanDerWaalsContact CD-ND2 3.3Å; E14-N18 PolarHBondContact O-N 3.15Å; E14-N18 PolarHBondContact O-ND2 3.23Å; E14-N18 PolarHBondContact OE1-ND2 3.21Å; L15-N18 PolarHBondContact O-N 3.44Å; A16-N18 VanDerWaalsContact C-N 3.34Å; A16-N18 PolarHBondContact O-N 3.09Å; N18-F22 WeakPolarHBondContact O-CB 2.86Å; N18-F22 PolarHBondContact O-N 3.15Å; N18-L94 HydrophobicContact CB-CD1 4.49Å; N18-L94 HydrophobicContact CB-CD2 3.68Å
19L98.7Very high97.1Very high0 Ų055.5 Ų55.50%026%0.26CS..Hα-helixtrans-64-50174-76.5165000112.3L15 A16 Y21 F22 L23 L94 V563 T566 L567 L570L15-L19 HydrophobicContact CD1-CD1 4.23Å; L15-L19 HydrophobicContact CD1-CG 4.29Å; L15-L19 HydrophobicContact CG-CD1 3.88Å; L15-L19 HydrophobicContact CG-CG 4.41Å; L15-L19 WeakPolarHBondContact O-CB 3.37Å; L15-L19 WeakPolarHBondContact O-CD1 3.25Å; L15-L19 WeakPolarHBondContact O-CG 3.46Å; L15-L19 PolarHBondContact O-N 3.38Å; A16-L19 PolarHBondContact O-N 2.98Å; L19-Y21 PolarHBondContact O-N 2.96Å; L19-F22 PolarHBondContact O-N 3.32Å; L19-L23 WeakPolarHBondContact O-CB 3.45Å; L19-L23 WeakPolarHBondContact O-CG 3.45Å; L19-L23 PolarHBondContact O-N 2.82Å; L19-L94 HydrophobicContact CD2-CB 3.78Å; L19-L94 HydrophobicContact CD2-CD1 4.33Å; L19-L94 HydrophobicContact CG-CB 4.42Å; L19-V563 HydrophobicContact CD2-CG1 3.42Å; L19-V563 VanDerWaalsContact CD2-CG1 3.42Å; L19-T566 HydrophobicContact CD1-CG2 3.83Å; L19-T566 HydrophobicContact CD2-CG2 4.33Å; L19-L567 HydrophobicContact CB-CB 4.34Å; L19-L567 HydrophobicContact CB-CD1 4.08Å; L19-L567 HydrophobicContact CD1-CB 4.17Å; L19-L567 HydrophobicContact CD1-CD1 4.27Å; L19-L570 HydrophobicContact CD1-CD2 3.68Å
20T98.5Very high97.4Very high3 Ų354.5 Ų54.52%0.01825%0.251CS..Hα-helixtrans-66.1-39.6-179.866.40000111.7A16 R17 S24 L449 P450 H452 L567A16-T20 PolarHBondContact O-N 3.16Å; R17-T20 PolarHBondContact O-OG1 2.73Å; T20-S24 VanDerWaalsContact O-CB 3.23Å; T20-S24 WeakPolarHBondContact O-CB 3.19Å; T20-S24 PolarHBondContact O-N 3.41Å; T20-S24 PolarHBondContact O-OG 3.47Å; T20-L449 HydrophobicContact CG2-CB 4.09Å; T20-L449 HydrophobicContact CG2-CD1 3.86Å; T20-P450 PolarHBondContact OG1-O 3.24Å; T20-H452 HydrophobicContact CG2-CB 3.93Å; T20-L567 HydrophobicContact CG2-CD1 4.16Å; T20-L567 HydrophobicContact CG2-CD2 3.95Å
21Y98.5Very high97.6Very high165 Ų16550 Ų5065%0.64723%0.231SC*.Hα-helixtrans-61.4-47.9174.9178.6-97.1000112.4R17 L19 S24 T25R17-Y21 WeakPolarHBondContact O-CB 3.29Å; R17-Y21 PolarHBondContact O-N 2.75Å; L19-Y21 PolarHBondContact O-N 2.96Å; Y21-S24 PolarHBondContact O-N 3.26Å; Y21-T25 WeakPolarHBondContact O-CB 3.43Å; Y21-T25 PolarHBondContact O-N 3.41Å; Y21-T25 PolarHBondContact O-OG1 3.44Å
22F98.6Very high97.7Very high11 Ų1145.6 Ų45.65%0.04821%0.212CC..Hα-helixtrans-67.4-45-178.7-177.7-108.6000112.1N18 L19 S24 T25 Y26 F87 T90 A91 L94 L560 V563N18-F22 WeakPolarHBondContact O-CB 2.86Å; N18-F22 PolarHBondContact O-N 3.15Å; L19-F22 PolarHBondContact O-N 3.32Å; F22-S24 VanDerWaalsContact C-N 3.33Å; F22-S24 PolarHBondContact O-N 3.02Å; F22-T25 PolarHBondContact O-N 2.89Å; F22-Y26 AromaticContact CD2-CD2 3.72Å; F22-Y26 HydrophobicContact CD2-CD2 3.72Å; F22-Y26 AromaticContact CD2-CE2 3.68Å; F22-Y26 HydrophobicContact CD2-CE2 3.68Å; F22-Y26 AromaticContact CE2-CD2 3.5Å; F22-Y26 HydrophobicContact CE2-CD2 3.5Å; F22-Y26 AromaticContact CE2-CE2 3.36Å; F22-Y26 HydrophobicContact CE2-CE2 3.36Å; F22-Y26 HydrophobicContact CG-CD2 4.36Å; F22-Y26 AromaticContact CZ-CD2 3.98Å; F22-Y26 HydrophobicContact CZ-CD2 3.98Å; F22-Y26 HydrophobicContact CZ-CE2 4.19Å; F22-Y26 WeakPolarHBondContact O-CD2 3.15Å; F22-Y26 PolarHBondContact O-N 3.01Å; F22-Y26 VanDerWaalsContact O-N 3.11Å; F22-F87 HydrophobicContact CE2-CD2 4.04Å; F22-F87 AromaticContact CZ-CD2 3.68Å; F22-F87 HydrophobicContact CZ-CD2 3.68Å; F22-F87 HydrophobicContact CZ-CE2 4.05Å; F22-F87 HydrophobicContact CZ-CG 4.45Å; F22-F87 WeakPolarHBondContact CZ-O 3.4Å; F22-T90 HydrophobicContact CB-CG2 4.42Å; F22-T90 HydrophobicContact CD1-CG2 4.27Å; F22-T90 HydrophobicContact CD2-CG2 3.38Å; F22-T90 HydrophobicContact CE1-CG2 4.4Å; F22-T90 HydrophobicContact CE2-CG2 3.54Å; F22-T90 HydrophobicContact CG-CG2 3.78Å; F22-T90 HydrophobicContact CZ-CG2 4.07Å; F22-A91 HydrophobicContact CE1-CB 3.93Å; F22-A91 HydrophobicContact CZ-CB 3.98Å; F22-L94 HydrophobicContact CB-CD1 3.71Å; F22-L94 HydrophobicContact CD1-CD1 3.98Å; F22-L94 HydrophobicContact CG-CD1 3.92Å; F22-L560 HydrophobicContact CD1-CD2 4.25Å; F22-L560 HydrophobicContact CE1-CD2 3.45Å; F22-L560 VanDerWaalsContact CE1-CD2 3.45Å; F22-L560 HydrophobicContact CZ-CD2 4.07Å; F22-V563 HydrophobicContact CD1-CG1 4.03Å; F22-V563 HydrophobicContact CE1-CG1 4.46Å; F22-V563 HydrophobicContact CE1-CG2 4.38Å
23L98.4Very high97.8Very high10 Ų1047.4 Ų47.45%0.05222%0.22CC..Hα-helixtrans-64-36.9175.4-70.8172.8000112.1L19 Y26 K27 L454 V563 V564 L567L19-L23 WeakPolarHBondContact O-CB 3.45Å; L19-L23 WeakPolarHBondContact O-CG 3.45Å; L19-L23 PolarHBondContact O-N 2.82Å; L23-Y26 CarbonylContact O-C 3.54Å; L23-Y26 PolarHBondContact O-N 3.32Å; L23-K27 VanDerWaalsContact O-CA 3.32Å; L23-K27 WeakPolarHBondContact O-CA 3.35Å; L23-K27 WeakPolarHBondContact O-CB 3.5Å; L23-K27 PolarHBondContact O-N 3.41Å; L23-L454 HydrophobicContact CD1-CD2 4.09Å; L23-V563 HydrophobicContact CD1-CG1 4.23Å; L23-V563 HydrophobicContact CD2-CB 4.12Å; L23-V563 HydrophobicContact CD2-CG1 3.8Å; L23-V563 HydrophobicContact CG-CG1 3.9Å; L23-V564 HydrophobicContact CD1-CG2 4.1Å; L23-V564 HydrophobicContact CD2-CG2 3.72Å; L23-L567 HydrophobicContact CD1-CB 4.42Å; L23-L567 HydrophobicContact CD1-CD2 3.83Å
24S97.8Very high97.7Very high51 Ų5144 Ų4436%0.35721%0.207SC..Hα-helixtrans-63.8-42.3173.3-62.80000112.2T20 Y21 F22 Y26 K27 G451T20-S24 VanDerWaalsContact O-CB 3.23Å; T20-S24 WeakPolarHBondContact O-CB 3.19Å; T20-S24 PolarHBondContact O-N 3.41Å; T20-S24 PolarHBondContact O-OG 3.47Å; Y21-S24 PolarHBondContact O-N 3.26Å; F22-S24 VanDerWaalsContact C-N 3.33Å; F22-S24 PolarHBondContact O-N 3.02Å; S24-Y26 VanDerWaalsContact C-N 3.34Å; S24-Y26 PolarHBondContact O-N 2.83Å; S24-K27 WeakPolarHBondContact O-CB 3.27Å; S24-K27 PolarHBondContact O-N 3.39Å; S24-G451 WeakPolarHBondContact OG-CA 3.46Å; S24-G451 PolarHBondContact OG-O 2.99Å
25T97.8Very high97.6Very high61 Ų6141.4 Ų41.437%0.37420%0.196SC..Hα-helixtrans-62.1-41.1179.6-57.20000111.7Y21 F22Y21-T25 WeakPolarHBondContact O-CB 3.43Å; Y21-T25 PolarHBondContact O-N 3.41Å; Y21-T25 PolarHBondContact O-OG1 3.44Å; F22-T25 PolarHBondContact O-N 2.89Å
26Y98.1Very high97.6Very high40 Ų4040.5 Ų40.516%0.15719%0.191CC..THydrogen-bonded Turntrans-105.122.8-177.7-61.9-78.2000113.5F22 L23 S24 H28 I29 S30 W50 F87F22-Y26 AromaticContact CD2-CD2 3.72Å; F22-Y26 HydrophobicContact CD2-CD2 3.72Å; F22-Y26 AromaticContact CD2-CE2 3.68Å; F22-Y26 HydrophobicContact CD2-CE2 3.68Å; F22-Y26 AromaticContact CE2-CD2 3.5Å; F22-Y26 HydrophobicContact CE2-CD2 3.5Å; F22-Y26 AromaticContact CE2-CE2 3.36Å; F22-Y26 HydrophobicContact CE2-CE2 3.36Å; F22-Y26 HydrophobicContact CG-CD2 4.36Å; F22-Y26 AromaticContact CZ-CD2 3.98Å; F22-Y26 HydrophobicContact CZ-CD2 3.98Å; F22-Y26 HydrophobicContact CZ-CE2 4.19Å; F22-Y26 WeakPolarHBondContact O-CD2 3.15Å; F22-Y26 PolarHBondContact O-N 3.01Å; F22-Y26 VanDerWaalsContact O-N 3.11Å; L23-Y26 CarbonylContact O-C 3.54Å; L23-Y26 PolarHBondContact O-N 3.32Å; S24-Y26 VanDerWaalsContact C-N 3.34Å; S24-Y26 PolarHBondContact O-N 2.83Å; Y26-H28 PolarHBondContact O-N 3.45Å; Y26-I29 HydrophobicContact CD1-CD1 4.15Å; Y26-I29 WeakPolarHBondContact O-CA 3.32Å; Y26-I29 WeakPolarHBondContact O-CB 3.19Å; Y26-I29 PolarHBondContact O-N 3.34Å; Y26-S30 PolarHBondContact O-N 2.7Å; Y26-W50 HydrophobicContact CD1-CH2 4.26Å; Y26-W50 AromaticContact CE1-CH2 3.65Å; Y26-W50 HydrophobicContact CE1-CH2 3.65Å; Y26-W50 HydrophobicContact CE1-CZ2 4.17Å; Y26-F87 AromaticContact CD1-CD2 3.56Å; Y26-F87 HydrophobicContact CD1-CD2 3.56Å; Y26-F87 AromaticContact CD1-CE2 3.72Å; Y26-F87 HydrophobicContact CD1-CE2 3.72Å; Y26-F87 AromaticContact CD2-CD2 3.71Å; Y26-F87 HydrophobicContact CD2-CD2 3.71Å; Y26-F87 HydrophobicContact CD2-CE2 4.05Å; Y26-F87 HydrophobicContact CE1-CB 4.39Å; Y26-F87 AromaticContact CE1-CD2 3.59Å; Y26-F87 HydrophobicContact CE1-CD2 3.59Å; Y26-F87 HydrophobicContact CE1-CE2 4.23Å; Y26-F87 HydrophobicContact CE1-CG 4.29Å; Y26-F87 AromaticContact CE2-CD2 3.76Å; Y26-F87 HydrophobicContact CE2-CD2 3.76Å; Y26-F87 AromaticContact CG-CD2 3.62Å; Y26-F87 HydrophobicContact CG-CD2 3.62Å; Y26-F87 AromaticContact CG-CE2 3.62Å; Y26-F87 HydrophobicContact CG-CE2 3.62Å; Y26-F87 AromaticContact CZ-CD2 3.69Å
27K97Very high97.6Very high90 Ų9040.6 Ų40.639%0.39119%0.191SC..Hα-helixtrans-57-34.6-176.1-173.8169.7-178.8171.70113.6L23 S24 I29 S30 D31L23-K27 VanDerWaalsContact O-CA 3.32Å; L23-K27 WeakPolarHBondContact O-CA 3.35Å; L23-K27 WeakPolarHBondContact O-CB 3.5Å; L23-K27 PolarHBondContact O-N 3.41Å; S24-K27 WeakPolarHBondContact O-CB 3.27Å; S24-K27 PolarHBondContact O-N 3.39Å; K27-I29 PolarHBondContact O-N 2.9Å; K27-S30 WeakPolarHBondContact CA-OG 3.25Å; K27-S30 PolarHBondContact O-N 3.01Å; K27-S30 PolarHBondContact O-OG 2.87Å; K27-D31 WeakPolarHBondContact CE-OD2 3.39Å; K27-D31 WeakPolarHBondContact CG-OD2 3.12Å; K27-D31 WeakPolarHBondContact O-CB 3.25Å; K27-D31 PolarHBondContact O-N 2.96Å
28H97.1Very high97.5Very high80 Ų8036.3 Ų36.337%0.3718%0.176SC..Hα-helixtrans-57.5-32.9174.559.9-82.5000112.5Y26 S32 Y553Y26-H28 PolarHBondContact O-N 3.45Å; H28-S32 WeakPolarHBondContact O-CB 3.09Å; H28-S32 PolarHBondContact O-OG 3.37Å; H28-Y553 PolarHBondContact O-OH 2.94Å
29I98.1Very high97.4Very high0 Ų035.4 Ų35.40%018%0.175CC..Hα-helixtrans-82.8-42.7175.7-46.5-175.9000111.1Y26 K27 L46 W50 F87 L556 A557 L560Y26-I29 HydrophobicContact CD1-CD1 4.15Å; Y26-I29 WeakPolarHBondContact O-CA 3.32Å; Y26-I29 WeakPolarHBondContact O-CB 3.19Å; Y26-I29 PolarHBondContact O-N 3.34Å; K27-I29 PolarHBondContact O-N 2.9Å; I29-L46 HydrophobicContact CD1-CD2 4.05Å; I29-L46 HydrophobicContact CG1-CD2 4.42Å; I29-W50 HydrophobicContact CD1-CZ3 4.13Å; I29-F87 HydrophobicContact CD1-CE2 4.32Å; I29-F87 HydrophobicContact CD1-CZ 4.27Å; I29-L556 HydrophobicContact CG2-CB 3.91Å; I29-A557 HydrophobicContact CG2-CB 4.05Å; I29-L560 HydrophobicContact CB-CD1 3.99Å; I29-L560 HydrophobicContact CG2-CD1 4.2Å
30S96.6Very high97.2Very high13 Ų1339.2 Ų39.29%0.09119%0.192CC..Hα-helixtrans-69.3-33.4-177.566.60000114Y26 K27 A458Y26-S30 PolarHBondContact O-N 2.7Å; K27-S30 WeakPolarHBondContact CA-OG 3.25Å; K27-S30 PolarHBondContact O-N 3.01Å; K27-S30 PolarHBondContact O-OG 2.87Å; S30-A458 PolarHBondContact O-N 2.73Å
31D96.5Very high97.2Very high44 Ų4443.4 Ų43.424%0.23521%0.214CC..THydrogen-bonded Turntrans-91.8-2.7-176.3-68.57.7000112.4K27 S455 K457K27-D31 WeakPolarHBondContact CE-OD2 3.39Å; K27-D31 WeakPolarHBondContact CG-OD2 3.12Å; K27-D31 WeakPolarHBondContact O-CB 3.25Å; K27-D31 PolarHBondContact O-N 2.96Å; D31-S455 VanDerWaalsContact CG-CB 3.48Å; D31-S455 WeakPolarHBondContact OD1-CB 3.29Å; D31-S455 PolarHBondContact OD1-OG 3.25Å; D31-S455 WeakPolarHBondContact OD2-CB 3.48Å; D31-S455 PolarHBondContact OD2-OG 3.39Å; D31-K457 WeakPolarHBondContact O-CG 3.44Å
32S96.6Very high97.2Very high11 Ų1136.2 Ų36.28%0.07719%0.187CC..  trans-69.2126.5-178.6-87.30000113.4H28 K457 Y553H28-S32 WeakPolarHBondContact O-CB 3.09Å; H28-S32 PolarHBondContact O-OG 3.37Å; S32-K457 WeakPolarHBondContact O-CE 3.4Å; S32-K457 WeakPolarHBondContact O-CG 3.08Å; S32-Y553 PolarHBondContact OG-OH 3.29Å
33F96.3Very high97.2Very high49 Ų4936.1 Ų36.122%0.21519%0.187CC..  trans-83.8112.2165.8-69.8-96.4000109.6I35 E36 L42 Y456 K457F33-I35 HydrophobicContact CB-CG1 4.35Å; F33-I35 PolarHBondContact O-N 2.84Å; F33-I35 VanDerWaalsContact O-N 3.1Å; F33-E36 HydrophobicContact CB-CB 4.35Å; F33-E36 HydrophobicContact CB-CG 3.84Å; F33-E36 WeakPolarHBondContact CB-OE2 3.48Å; F33-E36 WeakPolarHBondContact O-CA 3.34Å; F33-E36 WeakPolarHBondContact O-CB 3.37Å; F33-E36 PolarHBondContact O-N 3.24Å; F33-L42 WeakPolarHBondContact O-CD1 3.36Å; F33-Y456 HydrophobicContact CZ-CD1 4.46Å; F33-K457 HydrophobicContact CD1-CD 4Å; F33-K457 HydrophobicContact CD1-CG 4.42Å; F33-K457 HydrophobicContact CD2-CB 4.38Å; F33-K457 HydrophobicContact CD2-CG 4.2Å; F33-K457 HydrophobicContact CE1-CB 4.36Å; F33-K457 HydrophobicContact CE1-CD 4.02Å; F33-K457 HydrophobicContact CE1-CG 4.38Å; F33-K457 HydrophobicContact CE2-CB 3.84Å; F33-K457 HydrophobicContact CE2-CG 4.14Å; F33-K457 HydrophobicContact CG-CD 4.33Å; F33-K457 HydrophobicContact CG-CG 4.34Å; F33-K457 HydrophobicContact CZ-CB 3.83Å; F33-K457 HydrophobicContact CZ-CD 4.36Å; F33-K457 HydrophobicContact CZ-CG 4.24Å
34I96.1Very high97.1Very high10 Ų1038.3 Ų38.35%0.05121%0.206CC..G310 helixtrans-58.7-27.1-178.7-53.5-58.9000112.8E36 F37 H483 A487 V550 Y553 F554 A557I34-E36 PolarHBondContact O-N 2.87Å; I34-F37 VanDerWaalsContact O-CB 3.23Å; I34-F37 WeakPolarHBondContact O-CB 3.31Å; I34-F37 PolarHBondContact O-N 2.93Å; I34-H483 HydrophobicContact CG2-CB 3.96Å; I34-A487 WeakPolarHBondContact O-CB 3.35Å; I34-V550 HydrophobicContact CG2-CG1 3.78Å; I34-Y553 HydrophobicContact CD1-CD1 3.8Å; I34-Y553 HydrophobicContact CD1-CE1 4.29Å; I34-F554 HydrophobicContact CD1-CB 3.98Å; I34-F554 HydrophobicContact CD1-CD2 4.08Å; I34-F554 HydrophobicContact CD1-CG 4.49Å; I34-F554 HydrophobicContact CG1-CB 4.16Å; I34-F554 HydrophobicContact CG1-CD2 3.71Å; I34-F554 HydrophobicContact CG1-CG 4.27Å; I34-F554 HydrophobicContact CG2-CB 4.32Å; I34-A557 HydrophobicContact CD1-CB 4.49Å
35I96.3Very high97.2Very high23 Ų2338.8 Ų38.812%0.11821%0.207CC..G310 helixtrans-67.1-20.3173.869.2-179.6000112.5F33 F37 R486 A487 E490 R502F33-I35 HydrophobicContact CB-CG1 4.35Å; F33-I35 PolarHBondContact O-N 2.84Å; F33-I35 VanDerWaalsContact O-N 3.1Å; I35-F37 VanDerWaalsContact C-N 3.32Å; I35-R486 HydrophobicContact CG2-CB 3.72Å; I35-A487 VanDerWaalsContact O-CA 3.23Å; I35-A487 WeakPolarHBondContact O-CA 3.39Å; I35-E490 HydrophobicContact CB-CB 4.22Å; I35-E490 HydrophobicContact CB-CG 4.33Å; I35-E490 HydrophobicContact CG1-CG 4.24Å; I35-E490 WeakPolarHBondContact O-CB 3.13Å; I35-E490 VanDerWaalsContact O-CG 3.28Å; I35-E490 WeakPolarHBondContact O-CG 3.49Å; I35-R502 HydrophobicContact CD1-CB 4.03Å; I35-R502 HydrophobicContact CD1-CG 4Å; I35-R502 HydrophobicContact CG1-CG 4.34Å
36E96.4Very high97.2Very high7 Ų736 Ų363%0.03319%0.19CC..G310 helixtrans-92.311177.2-53.5-168.4109.300112.9F33 I34 F38 S39 E40 R494 R501 R502F33-E36 HydrophobicContact CB-CB 4.35Å; F33-E36 HydrophobicContact CB-CG 3.84Å; F33-E36 WeakPolarHBondContact CB-OE2 3.48Å; F33-E36 WeakPolarHBondContact O-CA 3.34Å; F33-E36 WeakPolarHBondContact O-CB 3.37Å; F33-E36 PolarHBondContact O-N 3.24Å; I34-E36 PolarHBondContact O-N 2.87Å; E36-F38 VanDerWaalsContact C-N 3.31Å; E36-F38 PolarHBondContact O-N 3.21Å; E36-S39 WeakPolarHBondContact CA-OG 3.36Å; E36-S39 PolarHBondContact O-N 3.48Å; E36-S39 VanDerWaalsContact O-N 3.17Å; E36-S39 PolarHBondContact O-OG 3.32Å; E36-E40 HydrophobicContact CB-CG 3.73Å; E36-E40 PolarHBondContact O-N 3.09Å; E36-R494 IonicContact OE1-NH1 3.77Å; E36-R494 PolarHBondContact OE1-NH1 2.82Å; E36-R501 IonicContact OE1-CZ 2.88Å; E36-R501 IonicContact OE1-NE 3.63Å; E36-R501 PolarHBondContact OE1-NE 3.28Å; E36-R501 IonicContact OE1-NH2 3.22Å; E36-R501 PolarHBondContact OE1-NH2 3.05Å; E36-R501 IonicContact OE2-NE 2.69Å; E36-R501 IonicContact OE2-NH2 3.9Å; E36-R501 PolarHBondContact OE2-NH2 3.38Å; E36-R502 HydrophobicContact CG-CG 3.91Å; E36-R502 IonicContact OE1-CZ 2.85Å; E36-R502 IonicContact OE1-NH1 2.8Å; E36-R502 WeakPolarHBondContact OE2-CD 3.26Å; E36-R502 IonicContact OE2-CZ 3.83Å; E36-R502 IonicContact OE2-NE 2.72Å; E36-R502 IonicContact OE2-NH1 3.43Å; E36-R502 PolarHBondContact OE2-NH1 2.89Å
37F98.3Very high97.1Very high2 Ų236.9 Ų36.91%0.00920%0.2CC..THydrogen-bonded Turntrans-52.1-42.1-173.8179.8-85.7000114.5I34 I35 D41 L42 W43 A487 R549 V550 Y553I34-F37 VanDerWaalsContact O-CB 3.23Å; I34-F37 WeakPolarHBondContact O-CB 3.31Å; I34-F37 PolarHBondContact O-N 2.93Å; I35-F37 VanDerWaalsContact C-N 3.32Å; F37-D41 WeakPolarHBondContact O-CA 3.46Å; F37-L42 HydrophobicContact CB-CD1 4.38Å; F37-L42 HydrophobicContact CD2-CB 4.01Å; F37-L42 PolarHBondContact O-N 3.14Å; F37-W43 HydrophobicContact CE2-CB 4.19Å; F37-W43 HydrophobicContact CE2-CE3 4.31Å; F37-W43 HydrophobicContact CZ-CB 3.79Å; F37-W43 HydrophobicContact CZ-CE3 4.2Å; F37-W43 HydrophobicContact CZ-CG 4.46Å; F37-A487 HydrophobicContact CB-CB 4.14Å; F37-R549 HydrophobicContact CZ-CB 3.79Å; F37-V550 HydrophobicContact CD1-CG2 3.69Å; F37-V550 HydrophobicContact CD2-CG2 4.38Å; F37-V550 HydrophobicContact CE1-CG2 3.74Å; F37-V550 HydrophobicContact CE2-CG2 4.42Å; F37-V550 HydrophobicContact CG-CG1 4.44Å; F37-V550 HydrophobicContact CG-CG2 4.03Å; F37-V550 HydrophobicContact CZ-CG2 4.11Å; F37-Y553 HydrophobicContact CD2-CG 4.24Å; F37-Y553 HydrophobicContact CE2-CD2 4.4Å; F37-Y553 HydrophobicContact CE2-CG 4.08Å
38F98.1Very high97.2Very high37 Ų3737.1 Ų37.116%0.16221%0.209CC..THydrogen-bonded Turntrans-91.2-27.4178.8-56.8-68000113.5E36 A487 M543 Q546 V550E36-F38 VanDerWaalsContact C-N 3.31Å; E36-F38 PolarHBondContact O-N 3.21Å; F38-A487 HydrophobicContact CD2-CB 3.84Å; F38-A487 HydrophobicContact CE2-CB 3.88Å; F38-M543 HydrophobicContact CB-CG 4.37Å; F38-M543 HydrophobicContact CB-SD 3.82Å; F38-M543 HydrophobicContact CD1-CB 4.26Å; F38-M543 HydrophobicContact CD1-CG 3.84Å; F38-M543 HydrophobicContact CD1-SD 4.34Å; F38-M543 HydrophobicContact CD2-CB 4.13Å; F38-M543 HydrophobicContact CD2-CG 3.98Å; F38-M543 HydrophobicContact CD2-SD 3.65Å; F38-M543 HydrophobicContact CE1-CB 3.98Å; F38-M543 HydrophobicContact CE1-CG 4.07Å; F38-M543 HydrophobicContact CE2-CB 3.84Å; F38-M543 HydrophobicContact CE2-CG 4.21Å; F38-M543 HydrophobicContact CE2-SD 4.3Å; F38-M543 HydrophobicContact CG-CB 4.34Å; F38-M543 HydrophobicContact CG-CG 3.81Å; F38-M543 HydrophobicContact CG-SD 3.68Å; F38-M543 HydrophobicContact CZ-CB 3.77Å; F38-M543 HydrophobicContact CZ-CG 4.26Å; F38-M543 VanDerWaalsContact CZ-O 3.24Å; F38-M543 WeakPolarHBondContact CZ-O 3.38Å; F38-Q546 HydrophobicContact CE1-CB 4.03Å; F38-Q546 HydrophobicContact CZ-CB 4.4Å; F38-V550 HydrophobicContact CE2-CG2 4.43Å; F38-V550 HydrophobicContact CZ-CG2 3.93Å
39S95Very high97.1Very high37 Ų3741.5 Ų41.526%0.25922%0.222SC..THydrogen-bonded Turntrans-86.3-16.3-17547.10000114E36E36-S39 WeakPolarHBondContact CA-OG 3.36Å; E36-S39 PolarHBondContact O-N 3.48Å; E36-S39 VanDerWaalsContact O-N 3.17Å; E36-S39 PolarHBondContact O-OG 3.32Å
40E96Very high97Very high79 Ų7941.6 Ų41.637%0.36922%0.223SC..THydrogen-bonded Turntrans-124.117.8173-43.4-87.6131.600111.5E36 L42 R494 R501E36-E40 HydrophobicContact CB-CG 3.73Å; E36-E40 PolarHBondContact O-N 3.09Å; E40-L42 HydrophobicContact CB-CD2 4.26Å; E40-L42 PolarHBondContact O-N 3.43Å; E40-R494 IonicContact OE1-CZ 3.75Å; E40-R494 IonicContact OE1-NH1 3.28Å; E40-R494 PolarHBondContact OE1-NH1 3.46Å; E40-R494 IonicContact OE1-NH2 3.47Å; E40-R494 PolarHBondContact OE1-NH2 3.43Å; E40-R501 IonicContact OE1-CZ 3.78Å; E40-R501 IonicContact OE1-NH1 2.82Å; E40-R501 IonicContact OE1-NH2 3.62Å; E40-R501 PolarHBondContact OE1-NH2 3.43Å; E40-R501 IonicContact OE2-CZ 2.72Å; E40-R501 IonicContact OE2-NH1 3.62Å; E40-R501 IonicContact OE2-NH2 3.26Å; E40-R501 PolarHBondContact OE2-NH2 2.93Å
41D97.2Very high97.1Very high91 Ų9142.9 Ų42.949%0.48723%0.227SC..THydrogen-bonded Turntrans35.660.7-176-165.92.7000114.7F37 W43 A44F37-D41 WeakPolarHBondContact O-CA 3.46Å; D41-W43 PolarHBondContact O-N 2.9Å; D41-W43 VanDerWaalsContact O-N 3.15Å; D41-A44 HydrophobicContact CB-CB 4.38Å; D41-A44 PolarHBondContact O-N 2.95Å; D41-A44 VanDerWaalsContact O-N 3.12Å; D41-A44 PolarHBondContact OD1-N 3.19Å; D41-A44 WeakPolarHBondContact OD2-CB 3.47Å
42L98.4Very high97Very high15 Ų1545.5 Ų45.58%0.07924%0.238CC..G310 helixtrans-61.9-28.2-174.4-64.2-173.8000112.5F33 F37 E40 A44 T45 Y553F33-L42 WeakPolarHBondContact O-CD1 3.36Å; F37-L42 HydrophobicContact CB-CD1 4.38Å; F37-L42 HydrophobicContact CD2-CB 4.01Å; F37-L42 PolarHBondContact O-N 3.14Å; E40-L42 HydrophobicContact CB-CD2 4.26Å; E40-L42 PolarHBondContact O-N 3.43Å; L42-A44 PolarHBondContact O-N 3.19Å; L42-T45 WeakPolarHBondContact O-CB 3.27Å; L42-T45 PolarHBondContact O-N 2.68Å; L42-T45 PolarHBondContact O-OG1 3.02Å; L42-Y553 HydrophobicContact CB-CD1 4.49Å; L42-Y553 HydrophobicContact CB-CD2 4.41Å; L42-Y553 HydrophobicContact CB-CE1 4.08Å; L42-Y553 HydrophobicContact CB-CE2 4.01Å; L42-Y553 HydrophobicContact CD1-CD1 4.5Å; L42-Y553 HydrophobicContact CD1-CE1 3.99Å; L42-Y553 WeakPolarHBondContact O-CE2 3.44Å
43W98.3Very high96.9Very high9 Ų946.9 Ų46.93%0.03424%0.244CC..G310 helixtrans-63.3-40.3177.2-171.4-100.5000112.5F37 D41 T45 L46 Q51 L54 C55 R549 V552F37-W43 HydrophobicContact CE2-CB 4.19Å; F37-W43 HydrophobicContact CE2-CE3 4.31Å; F37-W43 HydrophobicContact CZ-CB 3.79Å; F37-W43 HydrophobicContact CZ-CE3 4.2Å; F37-W43 HydrophobicContact CZ-CG 4.46Å; D41-W43 PolarHBondContact O-N 2.9Å; D41-W43 VanDerWaalsContact O-N 3.15Å; W43-T45 PolarHBondContact O-N 3.44Å; W43-L46 HydrophobicContact CE3-CD1 4.04Å; W43-L46 HydrophobicContact CZ3-CD1 4.05Å; W43-L46 PolarHBondContact O-N 3.45Å; W43-Q51 HydrophobicContact CZ2-CB 4.02Å; W43-Q51 HydrophobicContact CZ2-CG 4.35Å; W43-Q51 PolarHBondContact O-NE2 3.3Å; W43-L54 HydrophobicContact CH2-CB 3.83Å; W43-L54 HydrophobicContact CZ2-CB 4.48Å; W43-C55 HydrophobicContact CZ2-CB 3.94Å; W43-R549 HydrophobicContact CD2-CB 4.03Å; W43-R549 HydrophobicContact CD2-CG 4.1Å; W43-R549 HydrophobicContact CE3-CB 3.62Å; W43-R549 HydrophobicContact CE3-CG 4.08Å; W43-R549 HydrophobicContact CH2-CB 4.22Å; W43-R549 HydrophobicContact CH2-CG 4Å; W43-R549 HydrophobicContact CZ2-CG 4.05Å; W43-R549 HydrophobicContact CZ3-CB 3.72Å; W43-R549 HydrophobicContact CZ3-CG 4.02Å; W43-V552 HydrophobicContact CZ3-CB 4.33Å; W43-V552 HydrophobicContact CZ3-CG1 4.45Å
44A98.1Very high96.8Very high55 Ų5544.5 Ų44.546%0.45523%0.234SC..G310 helixtrans-64.9-21.9177.800000113.4D41 L42 L46D41-A44 HydrophobicContact CB-CB 4.38Å; D41-A44 PolarHBondContact O-N 2.95Å; D41-A44 VanDerWaalsContact O-N 3.12Å; D41-A44 PolarHBondContact OD1-N 3.19Å; D41-A44 WeakPolarHBondContact OD2-CB 3.47Å; L42-A44 PolarHBondContact O-N 3.19Å; A44-L46 VanDerWaalsContact C-N 3.25Å; A44-L46 PolarHBondContact O-N 2.99Å
45T97.9Very high96.7Very high61 Ų6145.9 Ų45.937%0.37424%0.244SC..G310 helixtrans-68.9-21.7176.5750000113.4L42 W43 Y553L42-T45 WeakPolarHBondContact O-CB 3.27Å; L42-T45 PolarHBondContact O-N 2.68Å; L42-T45 PolarHBondContact O-OG1 3.02Å; W43-T45 PolarHBondContact O-N 3.44Å; T45-Y553 PolarHBondContact OG1-OH 2.86Å
46L98.1Very high96.3Very high3 Ų351.1 Ų51.12%0.01627%0.272CS..SBendtrans-74.1145176.7-60.6-176.4000111I29 W43 A44 T48 W50 Q51 L54 Y553 L556I29-L46 HydrophobicContact CD1-CD2 4.05Å; I29-L46 HydrophobicContact CG1-CD2 4.42Å; W43-L46 HydrophobicContact CE3-CD1 4.04Å; W43-L46 HydrophobicContact CZ3-CD1 4.05Å; W43-L46 PolarHBondContact O-N 3.45Å; A44-L46 VanDerWaalsContact C-N 3.25Å; A44-L46 PolarHBondContact O-N 2.99Å; L46-T48 PolarHBondContact O-N 3.01Å; L46-W50 HydrophobicContact CD2-CE3 4.39Å; L46-Q51 HydrophobicContact CB-CG 3.93Å; L46-Q51 PolarHBondContact O-NE2 3.18Å; L46-L54 HydrophobicContact CD1-CD1 4.3Å; L46-Y553 HydrophobicContact CD1-CD2 3.85Å; L46-Y553 HydrophobicContact CD1-CE2 4.27Å; L46-Y553 HydrophobicContact CD2-CD2 4.03Å; L46-Y553 HydrophobicContact CD2-CE2 3.65Å; L46-Y553 HydrophobicContact CG-CD2 3.9Å; L46-Y553 HydrophobicContact CG-CE2 3.8Å; L46-L556 HydrophobicContact CD1-CD1 3.65Å; L46-L556 HydrophobicContact CD2-CD1 3.69Å; L46-L556 HydrophobicContact CG-CD1 4.35Å
47P97.6Very high96.2Very high59 Ų5951.5 Ų51.538%0.38328%0.275SS..  trans-53.1136.3173.2-25.533.8000111.9R49 W50 Q51P47-R49 PolarHBondContact O-N 3.28Å; P47-W50 HydrophobicContact CB-CB 4.46Å; P47-W50 HydrophobicContact CB-CG 4.06Å; P47-W50 HydrophobicContact CG-CD2 4.04Å; P47-W50 HydrophobicContact CG-CG 4.12Å; P47-W50 WeakPolarHBondContact O-CA 3.44Å; P47-W50 VanDerWaalsContact O-CB 3.3Å; P47-W50 WeakPolarHBondContact O-CB 3.22Å; P47-W50 PolarHBondContact O-N 3.33Å; P47-Q51 PolarHBondContact O-N 3.37Å
48T97.1Very high96.1Very high94 Ų9453.6 Ų53.658%0.57729%0.289SS*.Hα-helixtrans-55.1-34.7-174.8-400000113.2L46 W50 Q51 Q52L46-T48 PolarHBondContact O-N 3.01Å; T48-W50 VanDerWaalsContact C-N 3.33Å; T48-W50 PolarHBondContact O-N 2.9Å; T48-Q51 PolarHBondContact O-N 3.25Å; T48-Q52 WeakPolarHBondContact O-CG 3.47Å; T48-Q52 PolarHBondContact O-N 3.32Å
49R95.8Very high96Very high172 Ų17253.2 Ų53.265%0.64929%0.291SS*.Hα-helixtrans-70-24.8175.1-65.4-53.5-163.3173.15.9113.9P47 I53 P81P47-R49 PolarHBondContact O-N 3.28Å; R49-I53 WeakPolarHBondContact O-CG1 3.39Å; R49-P81 HydrophobicContact CB-CB 4.46Å; R49-P81 HydrophobicContact CB-CG 3.97Å; R49-P81 VanDerWaalsContact O-CG 3.29Å; R49-P81 WeakPolarHBondContact O-CG 3.28Å
50W97.3Very high96Very high2 Ų253 Ų531%0.00829%0.289CS..Hα-helixtrans-74.7-50.3169-65.619.6000109.1Y26 I29 L46 P47 T48 Q52 I53 L54 S83 L84 F87 L556Y26-W50 HydrophobicContact CD1-CH2 4.26Å; Y26-W50 AromaticContact CE1-CH2 3.65Å; Y26-W50 HydrophobicContact CE1-CH2 3.65Å; Y26-W50 HydrophobicContact CE1-CZ2 4.17Å; I29-W50 HydrophobicContact CD1-CZ3 4.13Å; L46-W50 HydrophobicContact CD2-CE3 4.39Å; P47-W50 HydrophobicContact CB-CB 4.46Å; P47-W50 HydrophobicContact CB-CG 4.06Å; P47-W50 HydrophobicContact CG-CD2 4.04Å; P47-W50 HydrophobicContact CG-CG 4.12Å; P47-W50 WeakPolarHBondContact O-CA 3.44Å; P47-W50 VanDerWaalsContact O-CB 3.3Å; P47-W50 WeakPolarHBondContact O-CB 3.22Å; P47-W50 PolarHBondContact O-N 3.33Å; T48-W50 VanDerWaalsContact C-N 3.33Å; T48-W50 PolarHBondContact O-N 2.9Å; W50-Q52 VanDerWaalsContact C-N 3.26Å; W50-Q52 PolarHBondContact O-N 3.3Å; W50-I53 PolarHBondContact O-N 3.09Å; W50-L54 HydrophobicContact CB-CD1 3.98Å; W50-L54 VanDerWaalsContact O-CB 3.22Å; W50-L54 WeakPolarHBondContact O-CB 3.47Å; W50-L54 VanDerWaalsContact O-CG 3.26Å; W50-L54 WeakPolarHBondContact O-CG 3.41Å; W50-L54 PolarHBondContact O-N 2.64Å; W50-S83 PolarHBondContact NE1-OG 3.39Å; W50-L84 HydrophobicContact CD2-CB 4.14Å; W50-L84 HydrophobicContact CD2-CD1 3.87Å; W50-L84 HydrophobicContact CE3-CD1 3.85Å; W50-L84 HydrophobicContact CG-CB 4.24Å; W50-L84 HydrophobicContact CG-CD1 4.42Å; W50-L84 HydrophobicContact CH2-CD1 4.34Å; W50-L84 HydrophobicContact CZ2-CB 4.28Å; W50-L84 HydrophobicContact CZ2-CD1 4.36Å; W50-L84 HydrophobicContact CZ3-CD1 4.09Å; W50-F87 HydrophobicContact CH2-CB 3.64Å; W50-F87 AromaticContact CH2-CD1 3.85Å; W50-F87 HydrophobicContact CH2-CD1 3.85Å; W50-F87 AromaticContact CH2-CD2 3.96Å; W50-F87 HydrophobicContact CH2-CD2 3.96Å; W50-F87 HydrophobicContact CH2-CE1 4.48Å; W50-F87 AromaticContact CH2-CG 3.55Å; W50-F87 HydrophobicContact CH2-CG 3.55Å; W50-F87 HydrophobicContact CZ2-CB 3.93Å; W50-F87 HydrophobicContact CZ2-CG 4.34Å; W50-F87 HydrophobicContact CZ3-CD1 4.16Å; W50-F87 HydrophobicContact CZ3-CE1 4.44Å; W50-F87 HydrophobicContact CZ3-CG 4.27Å; W50-L556 HydrophobicContact CE3-CD1 4.47Å; W50-L556 HydrophobicContact CZ3-CD2 4.38Å
51Q97.4Very high95.9Very high40 Ų4052.7 Ų52.719%0.18729%0.287CS..Hα-helixtrans-50.8-45.7179.2-62-178.63200112.3W43 L46 P47 T48 I53 L54 C55W43-Q51 HydrophobicContact CZ2-CB 4.02Å; W43-Q51 HydrophobicContact CZ2-CG 4.35Å; W43-Q51 PolarHBondContact O-NE2 3.3Å; L46-Q51 HydrophobicContact CB-CG 3.93Å; L46-Q51 PolarHBondContact O-NE2 3.18Å; P47-Q51 PolarHBondContact O-N 3.37Å; T48-Q51 PolarHBondContact O-N 3.25Å; Q51-I53 PolarHBondContact O-N 2.87Å; Q51-L54 PolarHBondContact O-N 2.96Å; Q51-C55 WeakPolarHBondContact O-CB 3.22Å; Q51-C55 PolarHBondContact O-N 2.66Å; Q51-C55 PolarHBondContact O-SG 2.96Å
52Q94.4Very high95.9Very high99 Ų9948.4 Ų48.446%0.46326%0.264SS..Hα-helixtrans-60.6-23.4178.8-77.8175.7-16.500115.5T48 W50T48-Q52 WeakPolarHBondContact O-CG 3.47Å; T48-Q52 PolarHBondContact O-N 3.32Å; W50-Q52 VanDerWaalsContact C-N 3.26Å; W50-Q52 PolarHBondContact O-N 3.3Å
53I93.9Very high95.8Very high40 Ų4047.7 Ų47.721%0.20526%0.26CS..Hα-helixtrans-108.4-24.8-176.4-60.5-53.2000111.2R49 W50 Q51 W80 P81R49-I53 WeakPolarHBondContact O-CG1 3.39Å; W50-I53 PolarHBondContact O-N 3.09Å; Q51-I53 PolarHBondContact O-N 2.87Å; I53-W80 HydrophobicContact CG2-CD2 4.23Å; I53-W80 HydrophobicContact CG2-CG 3.88Å; I53-W80 VanDerWaalsContact CG2-NE1 3.33Å; I53-P81 HydrophobicContact CG1-CG 4.45Å
54L95.8Very high95.5Very high0 Ų049.8 Ų49.80%027%0.272CS..Hα-helixtrans-89.5-20.6-178.4-72-175.7000113.5W43 L46 W50 Q51 D56 L57 L84 V552 L556W43-L54 HydrophobicContact CH2-CB 3.83Å; W43-L54 HydrophobicContact CZ2-CB 4.48Å; L46-L54 HydrophobicContact CD1-CD1 4.3Å; W50-L54 HydrophobicContact CB-CD1 3.98Å; W50-L54 VanDerWaalsContact O-CB 3.22Å; W50-L54 WeakPolarHBondContact O-CB 3.47Å; W50-L54 VanDerWaalsContact O-CG 3.26Å; W50-L54 WeakPolarHBondContact O-CG 3.41Å; W50-L54 PolarHBondContact O-N 2.64Å; Q51-L54 PolarHBondContact O-N 2.96Å; L54-D56 VanDerWaalsContact C-N 3.3Å; L54-D56 PolarHBondContact O-N 3.48Å; L54-L57 HydrophobicContact CD2-CD1 3.67Å; L54-L84 HydrophobicContact CD1-CD1 4.48Å; L54-L84 HydrophobicContact CD2-CD2 3.93Å; L54-L84 HydrophobicContact CG-CD2 4.19Å; L54-V552 HydrophobicContact CB-CG1 3.91Å; L54-V552 HydrophobicContact CD1-CG1 4.01Å; L54-V552 HydrophobicContact CD2-CG1 3.97Å; L54-V552 HydrophobicContact CG-CG1 4.18Å; L54-L556 HydrophobicContact CD1-CD1 3.94Å; L54-L556 HydrophobicContact CD1-CD2 4.45Å
55C94.1Very high95.3Very high38 Ų3847.6 Ų47.626%0.25725%0.253SS..THydrogen-bonded Turntrans-67.4-27.1-176.154.90000114.5W43 Q51W43-C55 HydrophobicContact CZ2-CB 3.94Å; Q51-C55 WeakPolarHBondContact O-CB 3.22Å; Q51-C55 PolarHBondContact O-N 2.66Å; Q51-C55 PolarHBondContact O-SG 2.96Å
56D87.8Confident95.1Very high134 Ų13444.7 Ų44.772%0.71724%0.235SC*.THydrogen-bonded Turntrans-107.69-169.3-56.1-18.8000113.1L54L54-D56 VanDerWaalsContact C-N 3.3Å; L54-D56 PolarHBondContact O-N 3.48Å
57L94.1Very high94.9Very high15 Ų1544.7 Ų44.78%0.07924%0.235CC..  trans-76.2126.6-179.6-61.7-177000111.8L54 Q61 I62 W80L54-L57 HydrophobicContact CD2-CD1 3.67Å; L57-Q61 HydrophobicContact CB-CB 4.42Å; L57-Q61 HydrophobicContact CD2-CB 4.35Å; L57-I62 HydrophobicContact CB-CD1 4.48Å; L57-I62 HydrophobicContact CB-CG1 3.77Å; L57-I62 HydrophobicContact CD1-CG1 4.36Å; L57-W80 HydrophobicContact CD1-CH2 4.08Å; L57-W80 HydrophobicContact CD1-CZ2 3.83Å; L57-W80 HydrophobicContact CD2-CZ2 4.11Å
58S94.9Very high94.6Very high45 Ų4542.9 Ų42.932%0.31522%0.222SC..  trans-71.7155.3169.468.50000111.6P60 Q61 I62S58-P60 VanDerWaalsContact C-N 3.34Å; S58-Q61 WeakPolarHBondContact O-CA 3.14Å; S58-Q61 WeakPolarHBondContact O-CB 3.37Å; S58-Q61 PolarHBondContact O-N 2.95Å; S58-Q61 WeakPolarHBondContact OG-CG 3.24Å; S58-Q61 PolarHBondContact OG-OE1 3.2Å; S58-I62 WeakPolarHBondContact O-CG1 3.31Å; S58-I62 PolarHBondContact O-N 3.4Å
59P96.4Very high94Very high30 Ų3044.6 Ų44.620%0.19522%0.218CC..Hα-helixtrans-50.5-42.5179.9-26.334.6000114.8Q61 I62 A63 L473 E476 L480P59-Q61 PolarHBondContact O-N 3.41Å; P59-I62 WeakPolarHBondContact O-CB 3.49Å; P59-I62 PolarHBondContact O-N 3.5Å; P59-A63 PolarHBondContact O-N 2.98Å; P59-A63 VanDerWaalsContact O-N 3.12Å; P59-L473 CarbonylContact C-O 3.58Å; P59-L473 HydrophobicContact CB-CD2 3.9Å; P59-L473 VanDerWaalsContact CB-O 3.26Å; P59-L473 WeakPolarHBondContact CB-O 3.5Å; P59-L473 WeakPolarHBondContact O-CB 3.35Å; P59-E476 HydrophobicContact CB-CG 4.39Å; P59-L480 HydrophobicContact CB-CD1 3.82Å; P59-L480 HydrophobicContact CG-CD1 4.08Å
60P95.6Very high93.4Very high33 Ų3341.2 Ų41.221%0.21421%0.212CC..Hα-helixtrans-65-36.8174.9-22.636000113.2S58 I62 A63 D64 E476S58-P60 VanDerWaalsContact C-N 3.34Å; P60-I62 VanDerWaalsContact C-N 3.31Å; P60-I62 PolarHBondContact O-N 3.3Å; P60-A63 WeakPolarHBondContact O-CB 3.17Å; P60-A63 PolarHBondContact O-N 3.23Å; P60-D64 WeakPolarHBondContact O-CB 3.39Å; P60-D64 PolarHBondContact O-N 3.23Å; P60-E476 HydrophobicContact CG-CG 3.82Å
61Q94.7Very high92.6Very high72 Ų7242.9 Ų42.934%0.33622%0.221SC..Hα-helixtrans-64.9-34.9174.4-70.4172.9-24.200112.1L57 S58 P59 D64 L65L57-Q61 HydrophobicContact CB-CB 4.42Å; L57-Q61 HydrophobicContact CD2-CB 4.35Å; S58-Q61 WeakPolarHBondContact O-CA 3.14Å; S58-Q61 WeakPolarHBondContact O-CB 3.37Å; S58-Q61 PolarHBondContact O-N 2.95Å; S58-Q61 WeakPolarHBondContact OG-CG 3.24Å; S58-Q61 PolarHBondContact OG-OE1 3.2Å; P59-Q61 PolarHBondContact O-N 3.41Å; Q61-D64 PolarHBondContact O-N 3.33Å; Q61-L65 HydrophobicContact CB-CD1 4.24Å; Q61-L65 WeakPolarHBondContact O-CB 3.38Å; Q61-L65 WeakPolarHBondContact O-CG 3.37Å; Q61-L65 PolarHBondContact O-N 3.03Å
62I96.1Very high91.4Very high1 Ų147.1 Ų47.11%0.00525%0.25CC..Iπ-helixtrans-64.3-43.4174.1-58.4168.6000110.2L57 S58 P59 P60 L66 L67 L473 V551 V552 S555L57-I62 HydrophobicContact CB-CD1 4.48Å; L57-I62 HydrophobicContact CB-CG1 3.77Å; L57-I62 HydrophobicContact CD1-CG1 4.36Å; S58-I62 WeakPolarHBondContact O-CG1 3.31Å; S58-I62 PolarHBondContact O-N 3.4Å; P59-I62 WeakPolarHBondContact O-CB 3.49Å; P59-I62 PolarHBondContact O-N 3.5Å; P60-I62 VanDerWaalsContact C-N 3.31Å; P60-I62 PolarHBondContact O-N 3.3Å; I62-L66 HydrophobicContact CG2-CD2 4.33Å; I62-L66 VanDerWaalsContact O-CB 3.31Å; I62-L66 WeakPolarHBondContact O-CB 3.4Å; I62-L66 PolarHBondContact O-N 2.64Å; I62-L67 PolarHBondContact O-N 2.87Å; I62-L67 VanDerWaalsContact O-N 3.15Å; I62-L473 HydrophobicContact CB-CD1 4.28Å; I62-L473 HydrophobicContact CB-CD2 4.33Å; I62-L473 HydrophobicContact CG2-CD1 3.96Å; I62-L473 HydrophobicContact CG2-CD2 4.41Å; I62-V551 HydrophobicContact CD1-CG1 3.73Å; I62-V552 HydrophobicContact CD1-CB 4.4Å; I62-V552 HydrophobicContact CD1-CG2 3.32Å; I62-V552 HydrophobicContact CG1-CG2 3.84Å; I62-S555 WeakPolarHBondContact CG2-OG 3.4Å
63A95.4Very high90.5Very high0 Ų049.2 Ų49.20%026%0.264CS..Iπ-helixtrans-60.2-51173.700000111.2P59 P60 L67 D68 M470 L473 R474P59-A63 PolarHBondContact O-N 2.98Å; P59-A63 VanDerWaalsContact O-N 3.12Å; P60-A63 WeakPolarHBondContact O-CB 3.17Å; P60-A63 PolarHBondContact O-N 3.23Å; A63-L67 PolarHBondContact O-N 2.9Å; A63-D68 VanDerWaalsContact O-CB 3.29Å; A63-D68 WeakPolarHBondContact O-CB 3.5Å; A63-D68 PolarHBondContact O-N 2.94Å; A63-M470 HydrophobicContact CB-CB 4.49Å; A63-M470 HydrophobicContact CB-CG 4.48Å; A63-L473 HydrophobicContact CB-CB 3.86Å; A63-L473 HydrophobicContact CB-CD1 4.11Å; A63-R474 HydrophobicContact CB-CG 3.8Å
64D92.9Very high89.9Confident52 Ų5249.9 Ų49.928%0.27826%0.264SS..Iπ-helixtrans-84.4-29.2-165.4-69.7-4.6000114.7P60 Q61 N71 R474P60-D64 WeakPolarHBondContact O-CB 3.39Å; P60-D64 PolarHBondContact O-N 3.23Å; Q61-D64 PolarHBondContact O-N 3.33Å; D64-N71 PolarHBondContact O-ND2 3.16Å; D64-R474 IonicContact OD1-CZ 2.85Å; D64-R474 IonicContact OD1-NE 4Å; D64-R474 PolarHBondContact OD1-NE 3.36Å; D64-R474 IonicContact OD1-NH2 3.99Å; D64-R474 PolarHBondContact OD1-NH2 2.78Å
65L93.3Very high89.2Confident9 Ų955 Ų555%0.04730%0.299CS..Iπ-helixtrans-99.6-33.6-178.2-55.6-179.3000113.2Q61 R74 Y76 W80 R88Q61-L65 HydrophobicContact CB-CD1 4.24Å; Q61-L65 WeakPolarHBondContact O-CB 3.38Å; Q61-L65 WeakPolarHBondContact O-CG 3.37Å; Q61-L65 PolarHBondContact O-N 3.03Å; L65-R74 HydrophobicContact CD2-CB 3.82Å; L65-R74 HydrophobicContact CD2-CG 4.07Å; L65-Y76 HydrophobicContact CB-CE1 4.12Å; L65-Y76 HydrophobicContact CD1-CD1 4.14Å; L65-Y76 HydrophobicContact CD1-CE1 4.47Å; L65-Y76 HydrophobicContact CD2-CD1 4.11Å; L65-Y76 HydrophobicContact CD2-CE1 4.04Å; L65-Y76 HydrophobicContact CG-CE1 4.44Å; L65-W80 HydrophobicContact CB-CH2 3.61Å; L65-W80 HydrophobicContact CB-CZ2 3.75Å; L65-W80 HydrophobicContact CB-CZ3 4.48Å; L65-W80 HydrophobicContact CD1-CZ2 3.91Å; L65-R88 WeakPolarHBondContact O-CD 3.48Å; L65-R88 PolarHBondContact O-NE 2.86Å; L65-R88 VanDerWaalsContact O-NE 3.09Å
66L93.6Very high88.7Confident0 Ų056.7 Ų56.70%030%0.301CS..Iπ-helixtrans-99.1-55.6-178.1-172.765000112.5I62 W80 L84 R88 L556 L559I62-L66 HydrophobicContact CG2-CD2 4.33Å; I62-L66 VanDerWaalsContact O-CB 3.31Å; I62-L66 WeakPolarHBondContact O-CB 3.4Å; I62-L66 PolarHBondContact O-N 2.64Å; L66-W80 HydrophobicContact CB-CH2 4.38Å; L66-W80 HydrophobicContact CD1-CZ3 4.35Å; L66-L84 HydrophobicContact CD1-CD1 4.4Å; L66-R88 VanDerWaalsContact O-CD 3.27Å; L66-R88 WeakPolarHBondContact O-CD 3.32Å; L66-R88 PolarHBondContact O-NE 2.96Å; L66-L556 HydrophobicContact CD1-CD2 3.99Å; L66-L556 HydrophobicContact CD2-CD2 3.88Å; L66-L556 HydrophobicContact CD2-CG 4.27Å; L66-L559 HydrophobicContact CD1-CD2 4.25Å
67L94.3Very high88.3Confident3 Ų355 Ų552%0.01630%0.299CS..Iπ-helixtrans-88.2-36.9-169.8-62.4-176.8000115.1I62 A63 R69 H92 I466 Y469 M470 L473 S555 L559I62-L67 PolarHBondContact O-N 2.87Å; I62-L67 VanDerWaalsContact O-N 3.15Å; A63-L67 PolarHBondContact O-N 2.9Å; L67-R69 PolarHBondContact O-N 2.86Å; L67-H92 PolarHBondContact O-CE1 2.85Å; L67-I466 HydrophobicContact CB-CG2 4.39Å; L67-Y469 HydrophobicContact CD1-CD1 3.88Å; L67-Y469 HydrophobicContact CD1-CE1 4.35Å; L67-M470 HydrophobicContact CB-CG 3.77Å; L67-M470 HydrophobicContact CB-SD 3.88Å; L67-M470 HydrophobicContact CD1-CG 3.95Å; L67-L473 HydrophobicContact CD1-CD1 3.6Å; L67-S555 WeakPolarHBondContact CD2-O 3.24Å; L67-L559 HydrophobicContact CD2-CB 4.14Å; L67-L559 HydrophobicContact CD2-CD1 4.22Å
68D90.6Very high87.9Confident22 Ų2256.9 Ų56.912%0.11831%0.313CS..  trans-73.2112.3-173.8-164.7-44.4000110.9A63 L70 N71 R74 R88 M470 R474A63-D68 VanDerWaalsContact O-CB 3.29Å; A63-D68 WeakPolarHBondContact O-CB 3.5Å; A63-D68 PolarHBondContact O-N 2.94Å; D68-L70 WeakPolarHBondContact OD1-CA 3.34Å; D68-L70 WeakPolarHBondContact OD1-CB 3.35Å; D68-L70 PolarHBondContact OD1-N 3.23Å; D68-N71 HydrophobicContact CB-CB 4.05Å; D68-N71 PolarHBondContact OD1-N 3.34Å; D68-R74 PolarHBondContact O-NH2 2.97Å; D68-R88 PolarHBondContact O-NH2 2.89Å; D68-M470 HydrophobicContact CB-CE 3.47Å; D68-M470 VanDerWaalsContact CB-CE 3.47Å; D68-M470 WeakPolarHBondContact OD2-CE 3.42Å; D68-R474 IonicContact OD2-CZ 3.17Å; D68-R474 IonicContact OD2-NH1 2.7Å; D68-R474 IonicContact OD2-NH2 3.97Å; D68-R474 PolarHBondContact OD2-NH2 3.38Å
69R86Confident87.6Confident130 Ų13061.4 Ų61.449%0.49134%0.339SS..SBendtrans-67.6-38.7173.9-176.7177.9178.7157.85.7112.8L67 R74 H92L67-R69 PolarHBondContact O-N 2.86Å; R69-R74 PolarHBondContact O-NH2 3.12Å; R69-H92 HydrophobicContact CG-CB 4.15Å; R69-H92 PolarHBondContact NH1-O 3.16Å; R69-H92 PolarHBondContact NH2-O 3.35Å
70L82.3Confident87.4Confident100 Ų10060.2 Ų60.252%0.52433%0.33SS..SBendtrans-86.2-23.7-167.2-58.2-179.8000114D68 V72 V108D68-L70 WeakPolarHBondContact OD1-CA 3.34Å; D68-L70 WeakPolarHBondContact OD1-CB 3.35Å; D68-L70 PolarHBondContact OD1-N 3.23Å; L70-V72 WeakPolarHBondContact O-CG2 3.22Å; L70-V72 PolarHBondContact O-N 2.88Å; L70-V108 HydrophobicContact CD1-CB 3.97Å; L70-V108 HydrophobicContact CD1-CG1 3.73Å; L70-V108 HydrophobicContact CD1-CG2 4.06Å
71N80.8Confident87.4Confident38 Ų3859.9 Ų59.920%0.20333%0.328CS..  trans-54.8109.3177.1-178.18.5000110.8D64 D68 N73 R74D64-N71 PolarHBondContact O-ND2 3.16Å; D68-N71 HydrophobicContact CB-CB 4.05Å; D68-N71 PolarHBondContact OD1-N 3.34Å; N71-N73 PolarHBondContact OD1-N 3.24Å; N71-N73 VanDerWaalsContact OD1-N 3.1Å; N71-R74 HydrophobicContact CB-CG 4.36Å; N71-R74 PolarHBondContact O-NH1 2.88Å; N71-R74 PolarHBondContact O-NH2 2.81Å
72V71.5Confident87.5Confident129 Ų12963.3 Ų63.378%0.78235%0.348SS*.  trans-81.9-34.3179.6-171.90000110.8L70 R74L70-V72 WeakPolarHBondContact O-CG2 3.22Å; L70-V72 PolarHBondContact O-N 2.88Å; V72-R74 PolarHBondContact O-N 2.93Å
73N75.8Confident87.5Confident142 Ų14266 Ų6676%0.75937%0.366SS*.  trans-96.953.9-169-63.2-9.8000111.7N71 S75N71-N73 PolarHBondContact OD1-N 3.24Å; N71-N73 VanDerWaalsContact OD1-N 3.1Å; N73-S75 PolarHBondContact O-N 3.42Å; N73-S75 VanDerWaalsContact O-N 3.09Å
74R82.2Confident87.6Confident55 Ų5566 Ų6621%0.20837%0.366CS..  trans-71.3103.3177.8-68.7-174.3-16479.910.3111L65 D68 R69 N71 V72 Y76L65-R74 HydrophobicContact CD2-CB 3.82Å; L65-R74 HydrophobicContact CD2-CG 4.07Å; D68-R74 PolarHBondContact O-NH2 2.97Å; R69-R74 PolarHBondContact O-NH2 3.12Å; N71-R74 HydrophobicContact CB-CG 4.36Å; N71-R74 PolarHBondContact O-NH1 2.88Å; N71-R74 PolarHBondContact O-NH2 2.81Å; V72-R74 PolarHBondContact O-N 2.93Å; R74-Y76 HydrophobicContact CB-CD2 4.17Å; R74-Y76 HydrophobicContact CB-CE2 3.6Å; R74-Y76 WeakPolarHBondContact CD-OH 3.37Å; R74-Y76 PolarHBondContact O-N 3.04Å
75S81.6Confident87.7Confident106 Ų10666.2 Ų66.274%0.74137%0.367SS*.  trans-81.7109.4167.3-169.60000109.6N73N73-S75 PolarHBondContact O-N 3.42Å; N73-S75 VanDerWaalsContact O-N 3.09Å
76Y82.6Confident87.9Confident75 Ų7567.8 Ų67.829%0.29438%0.382SS..  trans-94130.8175-65.5-83000109.8L65 R74 C78 W80L65-Y76 HydrophobicContact CB-CE1 4.12Å; L65-Y76 HydrophobicContact CD1-CD1 4.14Å; L65-Y76 HydrophobicContact CD1-CE1 4.47Å; L65-Y76 HydrophobicContact CD2-CD1 4.11Å; L65-Y76 HydrophobicContact CD2-CE1 4.04Å; L65-Y76 HydrophobicContact CG-CE1 4.44Å; R74-Y76 HydrophobicContact CB-CD2 4.17Å; R74-Y76 HydrophobicContact CB-CE2 3.6Å; R74-Y76 WeakPolarHBondContact CD-OH 3.37Å; R74-Y76 PolarHBondContact O-N 3.04Å; Y76-C78 WeakPolarHBondContact CB-O 3.29Å; Y76-C78 PolarHBondContact O-N 2.82Å; Y76-W80 AromaticContact CD1-CD1 3.71Å; Y76-W80 AromaticContact CD1-CD2 3.83Å; Y76-W80 HydrophobicContact CD1-CD2 3.83Å; Y76-W80 AromaticContact CD1-CE2 3.67Å; Y76-W80 AromaticContact CD1-CG 3.9Å; Y76-W80 HydrophobicContact CD1-CG 3.9Å; Y76-W80 HydrophobicContact CD1-CZ2 4.26Å; Y76-W80 AromaticContact CD1-NE1 3.59Å; Y76-W80 AromaticContact CE1-CD2 3.64Å; Y76-W80 HydrophobicContact CE1-CD2 3.64Å; Y76-W80 AromaticContact CE1-CE2 3.76Å; Y76-W80 AromaticContact CE1-CE3 3.9Å; Y76-W80 HydrophobicContact CE1-CE3 3.9Å; Y76-W80 HydrophobicContact CE1-CG 4.05Å; Y76-W80 HydrophobicContact CE1-CH2 4.38Å; Y76-W80 HydrophobicContact CE1-CZ2 4.14Å; Y76-W80 HydrophobicContact CE1-CZ3 4.26Å
77S79.8Confident88.1Confident98 Ų9867.9 Ų67.969%0.68538%0.382SS*.SBendtrans-65.8-20.8175.553.40000113.6
78C85.5Confident88.2Confident54 Ų5468.7 Ų68.737%0.36539%0.385SS..SBendtrans-160.2164.7-177.2550000110.1Y76 W80Y76-C78 WeakPolarHBondContact CB-O 3.29Å; Y76-C78 PolarHBondContact O-N 2.82Å; C78-W80 PolarHBondContact O-N 3.33Å
79V87.7Confident88.5Confident140 Ų14070.1 Ų70.185%0.84840%0.4SS*.  trans-72111.4177.8-178.60000110.1
80W93.4Very high89.1Confident6 Ų666.3 Ų66.32%0.02339%0.392CS..  trans-67.8148.9175.9-78.924.8000111.8I53 L57 L65 L66 Y76 C78 L82 L84 L85I53-W80 HydrophobicContact CG2-CD2 4.23Å; I53-W80 HydrophobicContact CG2-CG 3.88Å; I53-W80 VanDerWaalsContact CG2-NE1 3.33Å; L57-W80 HydrophobicContact CD1-CH2 4.08Å; L57-W80 HydrophobicContact CD1-CZ2 3.83Å; L57-W80 HydrophobicContact CD2-CZ2 4.11Å; L65-W80 HydrophobicContact CB-CH2 3.61Å; L65-W80 HydrophobicContact CB-CZ2 3.75Å; L65-W80 HydrophobicContact CB-CZ3 4.48Å; L65-W80 HydrophobicContact CD1-CZ2 3.91Å; L66-W80 HydrophobicContact CB-CH2 4.38Å; L66-W80 HydrophobicContact CD1-CZ3 4.35Å; Y76-W80 AromaticContact CD1-CD1 3.71Å; Y76-W80 AromaticContact CD1-CD2 3.83Å; Y76-W80 HydrophobicContact CD1-CD2 3.83Å; Y76-W80 AromaticContact CD1-CE2 3.67Å; Y76-W80 AromaticContact CD1-CG 3.9Å; Y76-W80 HydrophobicContact CD1-CG 3.9Å; Y76-W80 HydrophobicContact CD1-CZ2 4.26Å; Y76-W80 AromaticContact CD1-NE1 3.59Å; Y76-W80 AromaticContact CE1-CD2 3.64Å; Y76-W80 HydrophobicContact CE1-CD2 3.64Å; Y76-W80 AromaticContact CE1-CE2 3.76Å; Y76-W80 AromaticContact CE1-CE3 3.9Å; Y76-W80 HydrophobicContact CE1-CE3 3.9Å; Y76-W80 HydrophobicContact CE1-CG 4.05Å; Y76-W80 HydrophobicContact CE1-CH2 4.38Å; Y76-W80 HydrophobicContact CE1-CZ2 4.14Å; Y76-W80 HydrophobicContact CE1-CZ3 4.26Å; C78-W80 PolarHBondContact O-N 3.33Å; W80-L82 PolarHBondContact O-N 2.83Å; W80-L84 HydrophobicContact CD2-CD2 3.97Å; W80-L84 HydrophobicContact CE3-CD2 3.48Å; W80-L84 VanDerWaalsContact CE3-CD2 3.48Å; W80-L84 HydrophobicContact CE3-CG 3.87Å; W80-L84 HydrophobicContact CZ3-CD2 3.87Å; W80-L84 HydrophobicContact CZ3-CG 4.2Å; W80-L85 HydrophobicContact CB-CD1 4.19Å; W80-L85 HydrophobicContact CB-CD2 3.95Å; W80-L85 HydrophobicContact CB-CG 3.93Å; W80-L85 HydrophobicContact CE3-CD2 4.09Å
81P95.4Very high89.8Confident25 Ų2561.6 Ų61.616%0.16237%0.367CS..  trans-60.6137.4178.3-21.132.2000111.6R49 I53 S83 L84 L85R49-P81 HydrophobicContact CB-CB 4.46Å; R49-P81 HydrophobicContact CB-CG 3.97Å; R49-P81 VanDerWaalsContact O-CG 3.29Å; R49-P81 WeakPolarHBondContact O-CG 3.28Å; I53-P81 HydrophobicContact CG1-CG 4.45Å; P81-S83 PolarHBondContact O-N 3.09Å; P81-S83 VanDerWaalsContact O-N 3.11Å; P81-L84 HydrophobicContact CB-CB 4.43Å; P81-L84 WeakPolarHBondContact O-CB 3.4Å; P81-L84 PolarHBondContact O-N 2.92Å; P81-L85 PolarHBondContact O-N 3.37Å; P81-L85 VanDerWaalsContact O-N 3.08Å
82L95.9Very high90.5Very high145 Ų14560.9 Ų60.976%0.75936%0.362SS*.Hα-helixtrans-55.6-33.6179.6-178.660.4000112.6W80 L85 A86W80-L82 PolarHBondContact O-N 2.83Å; L82-L85 PolarHBondContact O-N 3.37Å; L82-A86 WeakPolarHBondContact O-CB 3.42Å; L82-A86 PolarHBondContact O-N 2.85Å
83S97.3Very high91.6Very high56 Ų5658.1 Ų58.139%0.39235%0.353SS..Hα-helixtrans-66.8-34.3175.552.60000113.7W50 P81 F87W50-S83 PolarHBondContact NE1-OG 3.39Å; P81-S83 PolarHBondContact O-N 3.09Å; P81-S83 VanDerWaalsContact O-N 3.11Å; S83-F87 VanDerWaalsContact O-CB 3.25Å; S83-F87 WeakPolarHBondContact O-CB 3.46Å; S83-F87 PolarHBondContact O-N 2.91Å
84L96.9Very high92.7Very high0 Ų052.4 Ų52.40%032%0.322CS..Hα-helixtrans-72.7-42.1175.2179.360000110.9W50 L54 L66 W80 P81 F87 R88 L556W50-L84 HydrophobicContact CD2-CB 4.14Å; W50-L84 HydrophobicContact CD2-CD1 3.87Å; W50-L84 HydrophobicContact CE3-CD1 3.85Å; W50-L84 HydrophobicContact CG-CB 4.24Å; W50-L84 HydrophobicContact CG-CD1 4.42Å; W50-L84 HydrophobicContact CH2-CD1 4.34Å; W50-L84 HydrophobicContact CZ2-CB 4.28Å; W50-L84 HydrophobicContact CZ2-CD1 4.36Å; W50-L84 HydrophobicContact CZ3-CD1 4.09Å; L54-L84 HydrophobicContact CD1-CD1 4.48Å; L54-L84 HydrophobicContact CD2-CD2 3.93Å; L54-L84 HydrophobicContact CG-CD2 4.19Å; L66-L84 HydrophobicContact CD1-CD1 4.4Å; W80-L84 HydrophobicContact CD2-CD2 3.97Å; W80-L84 HydrophobicContact CE3-CD2 3.48Å; W80-L84 VanDerWaalsContact CE3-CD2 3.48Å; W80-L84 HydrophobicContact CE3-CG 3.87Å; W80-L84 HydrophobicContact CZ3-CD2 3.87Å; W80-L84 HydrophobicContact CZ3-CG 4.2Å; P81-L84 HydrophobicContact CB-CB 4.43Å; P81-L84 WeakPolarHBondContact O-CB 3.4Å; P81-L84 PolarHBondContact O-N 2.92Å; L84-F87 HydrophobicContact CD1-CD1 4.43Å; L84-R88 WeakPolarHBondContact O-CB 3.49Å; L84-R88 PolarHBondContact O-N 2.84Å; L84-L556 HydrophobicContact CD1-CD2 4.27Å
85L95.3Very high93.3Very high57 Ų5750.7 Ų50.730%0.29832%0.318SS..Hα-helixtrans-63.6-41.9174.8-66174.2000111.4W80 P81 L82 A89W80-L85 HydrophobicContact CB-CD1 4.19Å; W80-L85 HydrophobicContact CB-CD2 3.95Å; W80-L85 HydrophobicContact CB-CG 3.93Å; W80-L85 HydrophobicContact CE3-CD2 4.09Å; P81-L85 PolarHBondContact O-N 3.37Å; P81-L85 VanDerWaalsContact O-N 3.08Å; L82-L85 PolarHBondContact O-N 3.37Å; L85-A89 VanDerWaalsContact O-CB 3.24Å; L85-A89 WeakPolarHBondContact O-CB 3.34Å; L85-A89 PolarHBondContact O-N 3.08Å
86A97.1Very high93.8Very high43 Ų4346.7 Ų46.736%0.35529%0.287SS..Hα-helixtrans-65.9-49.3175.100000111.9L82 R88 A89 T90L82-A86 WeakPolarHBondContact O-CB 3.42Å; L82-A86 PolarHBondContact O-N 2.85Å; A86-R88 VanDerWaalsContact C-N 3.29Å; A86-R88 PolarHBondContact O-N 2.87Å; A86-A89 PolarHBondContact O-N 3.33Å; A86-T90 WeakPolarHBondContact O-CB 3.38Å; A86-T90 PolarHBondContact O-N 2.84Å; A86-T90 PolarHBondContact O-OG1 2.86Å; A86-T90 VanDerWaalsContact O-OG1 3.04Å
87F98.3Very high94.1Very high1 Ų147.4 Ų47.40%0.00430%0.301CS..Hα-helixtrans-49.3-51.7173.7166.7-102000111.5F22 Y26 I29 W50 S83 L84 A91 L556 L559 L560F22-F87 HydrophobicContact CE2-CD2 4.04Å; F22-F87 AromaticContact CZ-CD2 3.68Å; F22-F87 HydrophobicContact CZ-CD2 3.68Å; F22-F87 HydrophobicContact CZ-CE2 4.05Å; F22-F87 HydrophobicContact CZ-CG 4.45Å; F22-F87 WeakPolarHBondContact CZ-O 3.4Å; Y26-F87 AromaticContact CD1-CD2 3.56Å; Y26-F87 HydrophobicContact CD1-CD2 3.56Å; Y26-F87 AromaticContact CD1-CE2 3.72Å; Y26-F87 HydrophobicContact CD1-CE2 3.72Å; Y26-F87 AromaticContact CD2-CD2 3.71Å; Y26-F87 HydrophobicContact CD2-CD2 3.71Å; Y26-F87 HydrophobicContact CD2-CE2 4.05Å; Y26-F87 HydrophobicContact CE1-CB 4.39Å; Y26-F87 AromaticContact CE1-CD2 3.59Å; Y26-F87 HydrophobicContact CE1-CD2 3.59Å; Y26-F87 HydrophobicContact CE1-CE2 4.23Å; Y26-F87 HydrophobicContact CE1-CG 4.29Å; Y26-F87 AromaticContact CE2-CD2 3.76Å; Y26-F87 HydrophobicContact CE2-CD2 3.76Å; Y26-F87 AromaticContact CG-CD2 3.62Å; Y26-F87 HydrophobicContact CG-CD2 3.62Å; Y26-F87 AromaticContact CG-CE2 3.62Å; Y26-F87 HydrophobicContact CG-CE2 3.62Å; Y26-F87 AromaticContact CZ-CD2 3.69Å; I29-F87 HydrophobicContact CD1-CE2 4.32Å; I29-F87 HydrophobicContact CD1-CZ 4.27Å; W50-F87 HydrophobicContact CH2-CB 3.64Å; W50-F87 AromaticContact CH2-CD1 3.85Å; W50-F87 HydrophobicContact CH2-CD1 3.85Å; W50-F87 AromaticContact CH2-CD2 3.96Å; W50-F87 HydrophobicContact CH2-CD2 3.96Å; W50-F87 HydrophobicContact CH2-CE1 4.48Å; W50-F87 AromaticContact CH2-CG 3.55Å; W50-F87 HydrophobicContact CH2-CG 3.55Å; W50-F87 HydrophobicContact CZ2-CB 3.93Å; W50-F87 HydrophobicContact CZ2-CG 4.34Å; W50-F87 HydrophobicContact CZ3-CD1 4.16Å; W50-F87 HydrophobicContact CZ3-CE1 4.44Å; W50-F87 HydrophobicContact CZ3-CG 4.27Å; S83-F87 VanDerWaalsContact O-CB 3.25Å; S83-F87 WeakPolarHBondContact O-CB 3.46Å; S83-F87 PolarHBondContact O-N 2.91Å; L84-F87 HydrophobicContact CD1-CD1 4.43Å; F87-A91 WeakPolarHBondContact O-CB 3.41Å; F87-A91 PolarHBondContact O-N 3.22Å; F87-L556 HydrophobicContact CD1-CD2 4.33Å; F87-L556 HydrophobicContact CE1-CD2 3.65Å; F87-L556 HydrophobicContact CZ-CD2 4.43Å; F87-L559 HydrophobicContact CD1-CD2 4.34Å; F87-L559 HydrophobicContact CE1-CD2 3.86Å; F87-L560 HydrophobicContact CE2-CD1 4.26Å; F87-L560 HydrophobicContact CE2-CD2 3.8Å; F87-L560 HydrophobicContact CE2-CG 4.17Å; F87-L560 HydrophobicContact CZ-CD1 4.39Å; F87-L560 HydrophobicContact CZ-CD2 4.11Å; F87-L560 HydrophobicContact CZ-CG 4.1Å
88R96.6Very high94.5Very high20 Ų2044.4 Ų44.48%0.07528%0.275CS..Hα-helixtrans-63.4-46.6179.2-178-172.7168.2-89-23.8112.6L65 L66 D68 L84 A86 A91 H92 L559L65-R88 WeakPolarHBondContact O-CD 3.48Å; L65-R88 PolarHBondContact O-NE 2.86Å; L65-R88 VanDerWaalsContact O-NE 3.09Å; L66-R88 VanDerWaalsContact O-CD 3.27Å; L66-R88 WeakPolarHBondContact O-CD 3.32Å; L66-R88 PolarHBondContact O-NE 2.96Å; D68-R88 PolarHBondContact O-NH2 2.89Å; L84-R88 WeakPolarHBondContact O-CB 3.49Å; L84-R88 PolarHBondContact O-N 2.84Å; A86-R88 VanDerWaalsContact C-N 3.29Å; A86-R88 PolarHBondContact O-N 2.87Å; R88-A91 PolarHBondContact O-N 3.12Å; R88-H92 PolarHBondContact NH2-CD2 3.48Å; R88-H92 PolarHBondContact NH2-NE2 2.86Å; R88-H92 PolarHBondContact O-CD2 3Å; R88-H92 PolarHBondContact O-N 2.83Å; R88-H92 VanDerWaalsContact O-N 3.15Å; R88-L559 HydrophobicContact CB-CD2 4.28Å; R88-L559 HydrophobicContact CG-CD2 4.09Å
89A96.4Very high94.3Very high53 Ų5345.4 Ų45.444%0.43828%0.279SS..Hα-helixtrans-62.9-44.4179.700000111.6L85 A86 H92 A93L85-A89 VanDerWaalsContact O-CB 3.24Å; L85-A89 WeakPolarHBondContact O-CB 3.34Å; L85-A89 PolarHBondContact O-N 3.08Å; A86-A89 PolarHBondContact O-N 3.33Å; A89-H92 PolarHBondContact O-N 2.88Å; A89-A93 VanDerWaalsContact O-CB 3.24Å; A89-A93 WeakPolarHBondContact O-CB 3.46Å; A89-A93 PolarHBondContact O-N 2.82Å
90T98.2Very high93.6Very high50 Ų5039.9 Ų39.931%0.30725%0.246SC..Hα-helixtrans-64.8-43.6177.5-600000111.8F22 A86 H92 A93 L94F22-T90 HydrophobicContact CB-CG2 4.42Å; F22-T90 HydrophobicContact CD1-CG2 4.27Å; F22-T90 HydrophobicContact CD2-CG2 3.38Å; F22-T90 HydrophobicContact CE1-CG2 4.4Å; F22-T90 HydrophobicContact CE2-CG2 3.54Å; F22-T90 HydrophobicContact CG-CG2 3.78Å; F22-T90 HydrophobicContact CZ-CG2 4.07Å; A86-T90 WeakPolarHBondContact O-CB 3.38Å; A86-T90 PolarHBondContact O-N 2.84Å; A86-T90 PolarHBondContact O-OG1 2.86Å; A86-T90 VanDerWaalsContact O-OG1 3.04Å; T90-H92 VanDerWaalsContact C-N 3.29Å; T90-H92 PolarHBondContact O-N 3.01Å; T90-A93 PolarHBondContact O-N 2.91Å; T90-A93 VanDerWaalsContact O-N 3.09Å; T90-L94 HydrophobicContact CG2-CD1 3.52Å; T90-L94 HydrophobicContact CG2-CG 3.87Å; T90-L94 WeakPolarHBondContact O-CB 3.42Å; T90-L94 WeakPolarHBondContact O-CG 3.46Å; T90-L94 PolarHBondContact O-N 2.91Å
91A97.6Very high92.2Very high1 Ų145.4 Ų45.41%0.00827%0.272CS..Hα-helixtrans-59.2-38.2175.300000112.6F22 F87 R88 T95 L559 V563F22-A91 HydrophobicContact CE1-CB 3.93Å; F22-A91 HydrophobicContact CZ-CB 3.98Å; F87-A91 WeakPolarHBondContact O-CB 3.41Å; F87-A91 PolarHBondContact O-N 3.22Å; R88-A91 PolarHBondContact O-N 3.12Å; A91-T95 WeakPolarHBondContact O-CG2 3.33Å; A91-T95 PolarHBondContact O-OG1 3.48Å; A91-L559 HydrophobicContact CB-CD2 4.26Å; A91-L559 HydrophobicContact CB-CG 3.89Å; A91-V563 HydrophobicContact CB-CG2 4.13Å
92H95.4Very high90.3Very high23 Ų2348.2 Ų48.211%0.10631%0.306CS..Hα-helixtrans-76-30.9172.6-68.4-38.4000114L67 R69 R88 A89 T90 T95 L559L67-H92 PolarHBondContact O-CE1 2.85Å; R69-H92 HydrophobicContact CG-CB 4.15Å; R69-H92 PolarHBondContact NH1-O 3.16Å; R69-H92 PolarHBondContact NH2-O 3.35Å; R88-H92 PolarHBondContact NH2-CD2 3.48Å; R88-H92 PolarHBondContact NH2-NE2 2.86Å; R88-H92 PolarHBondContact O-CD2 3Å; R88-H92 PolarHBondContact O-N 2.83Å; R88-H92 VanDerWaalsContact O-N 3.15Å; A89-H92 PolarHBondContact O-N 2.88Å; T90-H92 VanDerWaalsContact C-N 3.29Å; T90-H92 PolarHBondContact O-N 3.01Å; H92-T95 PolarHBondContact O-OG1 3.16Å; H92-T95 VanDerWaalsContact O-OG1 3.08Å; H92-L559 VanDerWaalsContact CE1-CD1 3.47Å; H92-L559 WeakPolarHBondContact CE1-CD1 3.44Å
93A95.7Very high88.4Confident71 Ų7145 Ų4559%0.58729%0.286SS*.Hα-helixtrans-78-36.4-176.500000113A89 T90 T95A89-A93 VanDerWaalsContact O-CB 3.24Å; A89-A93 WeakPolarHBondContact O-CB 3.46Å; A89-A93 PolarHBondContact O-N 2.82Å; T90-A93 PolarHBondContact O-N 2.91Å; T90-A93 VanDerWaalsContact O-N 3.09Å; A93-T95 VanDerWaalsContact C-N 3.26Å; A93-T95 PolarHBondContact O-N 2.91Å
94L96.8Very high85.9Confident21 Ų2151.6 Ų51.611%0.1130%0.302CS..SBendtrans-78.8-2.5-179-63.4179.5000114.1L15 N18 L19 F22 T90 T566L15-L94 HydrophobicContact CD1-CB 4.37Å; L15-L94 HydrophobicContact CD1-CD2 3.91Å; N18-L94 HydrophobicContact CB-CD1 4.49Å; N18-L94 HydrophobicContact CB-CD2 3.68Å; L19-L94 HydrophobicContact CD2-CB 3.78Å; L19-L94 HydrophobicContact CD2-CD1 4.33Å; L19-L94 HydrophobicContact CG-CB 4.42Å; F22-L94 HydrophobicContact CB-CD1 3.71Å; F22-L94 HydrophobicContact CD1-CD1 3.98Å; F22-L94 HydrophobicContact CG-CD1 3.92Å; T90-L94 HydrophobicContact CG2-CD1 3.52Å; T90-L94 HydrophobicContact CG2-CG 3.87Å; T90-L94 WeakPolarHBondContact O-CB 3.42Å; T90-L94 WeakPolarHBondContact O-CG 3.46Å; T90-L94 PolarHBondContact O-N 2.91Å; L94-T566 VanDerWaalsContact O-CG2 3.31Å; L94-T566 WeakPolarHBondContact O-CG2 3.17Å
95T94.8Very high83.6Confident19 Ų1963 Ų6312%0.11735%0.345CS..SBendtrans-100.1139.1-17244.60000113.4A91 H92 A93 P562 V563 T566A91-T95 WeakPolarHBondContact O-CG2 3.33Å; A91-T95 PolarHBondContact O-OG1 3.48Å; H92-T95 PolarHBondContact O-OG1 3.16Å; H92-T95 VanDerWaalsContact O-OG1 3.08Å; A93-T95 VanDerWaalsContact C-N 3.26Å; A93-T95 PolarHBondContact O-N 2.91Å; T95-P562 HydrophobicContact CG2-CB 3.87Å; T95-V563 HydrophobicContact CG2-CB 4.27Å; T95-V563 HydrophobicContact CG2-CG2 3.73Å; T95-T566 WeakPolarHBondContact CA-OG1 3.39Å
96F92.8Very high80.9Confident23 Ų2369.2 Ų69.210%0.10137%0.372CS..PPolyproline II helixtrans-60.3140.1177.3-77.2-57.8000111.4L7 L15 R98 T566 L569 L570 M573 L585 L598L7-F96 HydrophobicContact CD1-CE1 4.09Å; L15-F96 HydrophobicContact CD2-CE1 4.17Å; L15-F96 HydrophobicContact CD2-CZ 4.24Å; F96-R98 PolarHBondContact O-N 3.1Å; F96-T566 HydrophobicContact CD2-CG2 3.3Å; F96-T566 HydrophobicContact CE2-CG2 3.51Å; F96-T566 HydrophobicContact CG-CG2 3.91Å; F96-T566 HydrophobicContact CZ-CG2 4.28Å; F96-T566 PolarHBondContact N-OG1 2.88Å; F96-L569 HydrophobicContact CD2-CB 4.47Å; F96-L569 HydrophobicContact CE2-CB 4.27Å; F96-L570 HydrophobicContact CE2-CB 4.02Å; F96-L570 HydrophobicContact CZ-CB 4.13Å; F96-L570 HydrophobicContact CZ-CD1 4.13Å; F96-M573 HydrophobicContact CZ-SD 4.05Å; F96-L585 HydrophobicContact CD1-CD1 4.22Å; F96-L585 HydrophobicContact CD2-CD1 3.4Å; F96-L585 VanDerWaalsContact CD2-CD1 3.4Å; F96-L585 HydrophobicContact CE1-CD1 4.06Å; F96-L585 HydrophobicContact CE2-CD1 3.21Å; F96-L585 HydrophobicContact CG-CD1 3.93Å; F96-L585 HydrophobicContact CZ-CD1 3.57Å; F96-L598 HydrophobicContact CB-CD1 3.88Å
97P89.3Confident78.4Confident90 Ų9070.9 Ų70.958%0.58437%0.373SS*.PPolyproline II helixtrans-60.8120.3178.5-24.835000112.6
98R87.3Confident75.8Confident35 Ų3575.2 Ų75.213%0.13240%0.399CS..  trans-89.2-7.9-178.7-64.2167.571.180.4-7.7113.9F96 E467 E565 P591 P595 N597F96-R98 PolarHBondContact O-N 3.1Å; R98-E467 IonicContact CZ-OE1 3.26Å; R98-E467 VanDerWaalsContact CZ-OE1 3.27Å; R98-E467 IonicContact NE-OE1 3.87Å; R98-E467 PolarHBondContact NE-OE1 2.98Å; R98-E467 IonicContact NH2-OE1 2.65Å; R98-E467 PolarHBondContact NH2-OE1 3.25Å; R98-E467 IonicContact NH2-OE2 3.76Å; R98-E565 IonicContact CZ-OE2 3.84Å; R98-E565 IonicContact NH1-OE2 2.71Å; R98-E565 PolarHBondContact NH1-OE2 3.07Å; R98-P591 HydrophobicContact CB-CB 4.37Å; R98-P595 PolarHBondContact NH2-O 3.04Å; R98-N597 PolarHBondContact O-ND2 3.22Å
99T81.3Confident73.4Confident75 Ų7577.5 Ų77.546%0.4643%0.429SS..SBendtrans-84.4125.6-177.7-48.10000111.2P587T99-P587 VanDerWaalsContact O-CG 3.28Å; T99-P587 WeakPolarHBondContact O-CG 3.24Å
100P73.9Confident71.4Confident23 Ų2380 Ų8015%0.14943%0.432CS..PPolyproline II helixtrans-58.5142.8173.7-25.635.4000113.1P587P100-P587 WeakPolarHBondContact CA-O 3.34Å; P100-P587 WeakPolarHBondContact CB-O 3.46Å
101Q63.5Low69.6Low122 Ų12281.1 Ų81.157%0.5744%0.437SS*.THydrogen-bonded Turntrans-66.2136.1178-65.7-1803.600110.9
102G56.8Low68.2Low84 Ų8483.8 Ų83.887%0.86645%0.448SS*.THydrogen-bonded Turntrans98.7-22.9175.800000115.9
103K54.9Low67.6Low78 Ų7883 Ų8334%0.33945%0.445SS..  trans-67.2143.3172.1-71.9-160.8171.3-162.30111.3D590K103-D590 IonicContact NZ-OD2 2.99Å; K103-D590 PolarHBondContact NZ-OD2 3.34Å
104R44.9Very low66.9Low195 Ų19585.8 Ų85.874%0.73645%0.446SS*.  trans-76.2148.7178.9-65.8-175.7177.8-164.52.5110.3H106 E107R104-H106 PolarHBondContact O-N 3.31Å; R104-E107 PolarHBondContact N-OE2 3.18Å; R104-E107 PolarHBondContact O-N 3.48Å
105R47.8Very low66.3Low238 Ų23885.3 Ų85.390%0.89844%0.443SS*.THydrogen-bonded Turntrans-57.2-14-179.7-76.8-175.4174.9178.3-0.9115.3
106H39.2Very low65.9Low188 Ų18884.6 Ų84.687%0.8744%0.438SS*.THydrogen-bonded Turntrans-97.5-8.4-175.2-85.3-88.7000115.4R104 V108R104-H106 PolarHBondContact O-N 3.31Å; H106-V108 VanDerWaalsContact C-N 3.32Å
107E44.8Very low65.5Low79 Ų7988.2 Ų88.237%0.36946%0.458SS..  trans-86.91.3179.8-73.8135.3-148.400113.6R104 G109 M110R104-E107 PolarHBondContact N-OE2 3.18Å; R104-E107 PolarHBondContact O-N 3.48Å; E107-G109 PolarHBondContact O-N 3.16Å; E107-M110 PolarHBondContact O-N 3.49Å
108V44.1Very low65.2Low92 Ų9292.9 Ų92.956%0.55847%0.472SS*.THydrogen-bonded Turntrans-75.473179.3-167.30000110.4L70 H106L70-V108 HydrophobicContact CD1-CB 3.97Å; L70-V108 HydrophobicContact CD1-CG1 3.73Å; L70-V108 HydrophobicContact CD1-CG2 4.06Å; H106-V108 VanDerWaalsContact C-N 3.32Å
109G46.3Very low65.1Low68 Ų6894.9 Ų94.970%0.70149%0.485SS*.THydrogen-bonded Turntrans-175.7-16.9-177.300000113.4E107 L111E107-G109 PolarHBondContact O-N 3.16Å; G109-L111 PolarHBondContact O-N 2.99Å
110M53.7Low65.2Low104 Ų10498 Ų9851%0.51249%0.492SS..  trans-79.2116.3170.7-57-157.681.200110.7E107 K112 L117E107-M110 PolarHBondContact O-N 3.49Å; M110-K112 PolarHBondContact O-N 3.17Å; M110-L117 HydrophobicContact CE-CD2 3.54Å
111L61.2Low65.8Low75 Ų7599.4 Ų99.439%0.39350%0.503SS..SBendtrans-64-4.8178.1-69.4-179.5000115.4G109 H471G109-L111 PolarHBondContact O-N 2.99Å; L111-H471 HydrophobicContact CD2-CB 4.3Å
112K68.8Low66.9Low57 Ų5796.6 Ų96.625%0.24849%0.49CS..SBendtrans-141.9143.2-177.4-66.6-168.2175.6-1750110.6M110 F116 K120 F593M110-K112 PolarHBondContact O-N 3.17Å; K112-F116 HydrophobicContact CB-CB 4.39Å; K112-F116 HydrophobicContact CD-CB 4.35Å; K112-K120 PolarHBondContact NZ-O 3.49Å; K112-F593 HydrophobicContact CD-CE2 4.29Å; K112-F593 HydrophobicContact CG-CD2 4.13Å; K112-F593 HydrophobicContact CG-CE2 4.03Å
113P80.8Confident68.4Low6 Ų692.6 Ų92.64%0.03945%0.449CS..  trans-58154.3169.8-21.430.5000112.4E115 F116 D590 F593P113-E115 HydrophobicContact CB-CG 4.22Å; P113-E115 PolarHBondContact O-N 2.83Å; P113-E115 VanDerWaalsContact O-N 3.08Å; P113-F116 HydrophobicContact CB-CD2 4.22Å; P113-F116 HydrophobicContact CB-CE2 4.48Å; P113-F116 HydrophobicContact CG-CD2 4.24Å; P113-F116 HydrophobicContact CG-CE2 4.28Å; P113-F116 PolarHBondContact O-N 2.93Å; P113-D590 HydrophobicContact CG-CB 3.84Å; P113-F593 HydrophobicContact CG-CB 4.18Å; P113-F593 HydrophobicContact CG-CD1 3.82Å; P113-F593 HydrophobicContact CG-CE1 4.45Å; P113-F593 HydrophobicContact CG-CG 4.15Å
114E82.9Confident70Confident130 Ų13092 Ų9261%0.60746%0.455SS*.G310 helixtrans-54-31.9-177.7-61.2174.2129.100113.2F116 L117E114-F116 PolarHBondContact O-N 2.99Å; E114-L117 HydrophobicContact CB-CD1 4.09Å; E114-L117 HydrophobicContact CG-CD1 4.41Å; E114-L117 WeakPolarHBondContact O-CB 3.23Å; E114-L117 VanDerWaalsContact O-CG 3.27Å; E114-L117 WeakPolarHBondContact O-CG 3.38Å; E114-L117 PolarHBondContact O-N 3.29Å; E114-L117 VanDerWaalsContact O-N 3.1Å
115E83.6Confident72.1Confident11 Ų1187.4 Ų87.45%0.05144%0.444CS..G310 helixtrans-63-9.5178.977.6-165.7129.800114.7P113 S123 S124 L125 H140P113-E115 HydrophobicContact CB-CG 4.22Å; P113-E115 PolarHBondContact O-N 2.83Å; P113-E115 VanDerWaalsContact O-N 3.08Å; E115-S123 WeakPolarHBondContact O-CA 3.23Å; E115-S123 VanDerWaalsContact OE2-CB 3.23Å; E115-S123 WeakPolarHBondContact OE2-CB 3.27Å; E115-S123 PolarHBondContact OE2-OG 2.63Å; E115-S124 WeakPolarHBondContact CA-OG 3.33Å; E115-S124 PolarHBondContact O-N 3.22Å; E115-L125 HydrophobicContact CB-CB 4.39Å; E115-L125 HydrophobicContact CB-CD1 3.92Å; E115-L125 HydrophobicContact CB-CG 3.77Å; E115-H140 IonicContact OE1-CE1 2.64Å; E115-H140 IonicContact OE1-CG 3.41Å; E115-H140 IonicContact OE1-ND1 3.18Å; E115-H140 PolarHBondContact OE1-ND1 2.94Å
116F86.6Confident74.1Confident3 Ų376.1 Ų76.11%0.01340%0.401CS..G310 helixtrans-113.410.6177.4-58.9-79.5000113.9K112 P113 E114 N119 K120 S123 P136 Q139 H140 F593K112-F116 HydrophobicContact CB-CB 4.39Å; K112-F116 HydrophobicContact CD-CB 4.35Å; P113-F116 HydrophobicContact CB-CD2 4.22Å; P113-F116 HydrophobicContact CB-CE2 4.48Å; P113-F116 HydrophobicContact CG-CD2 4.24Å; P113-F116 HydrophobicContact CG-CE2 4.28Å; P113-F116 PolarHBondContact O-N 2.93Å; E114-F116 PolarHBondContact O-N 2.99Å; F116-N119 WeakPolarHBondContact CA-O 3.37Å; F116-N119 CarbonylContact O-C 3.55Å; F116-K120 WeakPolarHBondContact O-CA 3.48Å; F116-K120 PolarHBondContact O-N 3.11Å; F116-S123 VanDerWaalsContact CE1-N 3.3Å; F116-P136 HydrophobicContact CD1-CB 4.37Å; F116-P136 HydrophobicContact CE1-CB 3.81Å; F116-P136 HydrophobicContact CZ-CB 4.3Å; F116-P136 VanDerWaalsContact CZ-O 3.3Å; F116-P136 WeakPolarHBondContact CZ-O 3.39Å; F116-Q139 HydrophobicContact CZ-CB 4.5Å; F116-H140 HydrophobicContact CE2-CB 4.09Å; F116-H140 HydrophobicContact CZ-CB 4.26Å; F116-F593 AromaticContact CD2-CE1 3.92Å; F116-F593 HydrophobicContact CD2-CE1 3.92Å; F116-F593 AromaticContact CD2-CZ 3.93Å; F116-F593 HydrophobicContact CD2-CZ 3.93Å; F116-F593 HydrophobicContact CE1-CZ 4.39Å; F116-F593 HydrophobicContact CE2-CD1 4.15Å; F116-F593 AromaticContact CE2-CE1 3.27Å; F116-F593 HydrophobicContact CE2-CE1 3.27Å; F116-F593 AromaticContact CE2-CZ 3.65Å; F116-F593 HydrophobicContact CE2-CZ 3.65Å; F116-F593 HydrophobicContact CG-CZ 4.43Å; F116-F593 AromaticContact CZ-CE1 3.67Å; F116-F593 HydrophobicContact CZ-CE1 3.67Å; F116-F593 AromaticContact CZ-CZ 3.9Å; F116-F593 HydrophobicContact CZ-CZ 3.9Å
117L83.7Confident76.3Confident100 Ų10068.9 Ų68.952%0.52438%0.377SS..SBendtrans-67-51-179.9-67.4171.5000111.9M110 E114M110-L117 HydrophobicContact CE-CD2 3.54Å; E114-L117 HydrophobicContact CB-CD1 4.09Å; E114-L117 HydrophobicContact CG-CD1 4.41Å; E114-L117 WeakPolarHBondContact O-CB 3.23Å; E114-L117 VanDerWaalsContact O-CG 3.27Å; E114-L117 WeakPolarHBondContact O-CG 3.38Å; E114-L117 PolarHBondContact O-N 3.29Å; E114-L117 VanDerWaalsContact O-N 3.1Å
118E83.6Confident78.4Confident188 Ų18870.3 Ų70.388%0.87938%0.384SS*.SBendtrans-66.9-37.6175.3-62.2179.616900111.9
119N84.3Confident80.5Confident76 Ų7667.7 Ų67.741%0.40637%0.366SS..  trans-138.9104.7-178.7-167.5-48.5000111.6F116 S121 Q122F116-N119 WeakPolarHBondContact CA-O 3.37Å; F116-N119 CarbonylContact O-C 3.55Å; N119-S121 PolarHBondContact O-N 3.16Å; N119-S121 PolarHBondContact OD1-N 3.42Å; N119-Q122 HydrophobicContact CB-CB 4.1Å; N119-Q122 PolarHBondContact O-N 3.25Å; N119-Q122 VanDerWaalsContact O-N 3.14Å; N119-Q122 PolarHBondContact OD1-N 3.39Å; N119-Q122 VanDerWaalsContact OD1-N 3.15Å
120K83.4Confident82.6Confident140 Ų14065.6 Ų65.661%0.60934%0.338SS*.THydrogen-bonded Turntrans-56.3-8.7-179.3-68.2-175.8-178.8-178.20115.4K112 F116K112-K120 PolarHBondContact NZ-O 3.49Å; F116-K120 WeakPolarHBondContact O-CA 3.48Å; F116-K120 PolarHBondContact O-N 3.11Å
121S86.5Confident84.5Confident54 Ų5463.2 Ų63.238%0.37832%0.323SS..THydrogen-bonded Turntrans-127.9-2.5-174.8-62.50000114.9N119 Q139N119-S121 PolarHBondContact O-N 3.16Å; N119-S121 PolarHBondContact OD1-N 3.42Å; S121-Q139 PolarHBondContact O-NE2 3.1Å
122Q87.4Confident85.7Confident63 Ų6364.8 Ų64.829%0.29433%0.327SS..SBendtrans-142.1116.6-174.6-62-71.5-75.600110.6N119 S124N119-Q122 HydrophobicContact CB-CB 4.1Å; N119-Q122 PolarHBondContact O-N 3.25Å; N119-Q122 VanDerWaalsContact O-N 3.14Å; N119-Q122 PolarHBondContact OD1-N 3.39Å; N119-Q122 VanDerWaalsContact OD1-N 3.15Å; Q122-S124 PolarHBondContact O-N 3.08Å
123S88.8Confident86.7Confident0 Ų066.8 Ų66.80%034%0.337CS..  trans-64.5124.3177155.60000110.8E115 F116 L125 L126 R131E115-S123 WeakPolarHBondContact O-CA 3.23Å; E115-S123 VanDerWaalsContact OE2-CB 3.23Å; E115-S123 WeakPolarHBondContact OE2-CB 3.27Å; E115-S123 PolarHBondContact OE2-OG 2.63Å; F116-S123 VanDerWaalsContact CE1-N 3.3Å; S123-L125 VanDerWaalsContact C-N 3.26Å; S123-L125 PolarHBondContact O-N 3.32Å; S123-L125 PolarHBondContact OG-N 2.98Å; S123-L126 PolarHBondContact OG-N 3.03Å; S123-R131 PolarHBondContact O-NE 2.82Å; S123-R131 PolarHBondContact O-NH2 3.13Å
124S88.1Confident87.3Confident66 Ų6667 Ų6746%0.46234%0.338SS..SBendtrans-64-31.2171.963.80000112.6E115 Q122E115-S124 WeakPolarHBondContact CA-OG 3.33Å; E115-S124 PolarHBondContact O-N 3.22Å; Q122-S124 PolarHBondContact O-N 3.08Å
125L88.3Confident87.8Confident98 Ų9869 Ų6951%0.51335%0.345SS..SBendtrans-79.2-21.1-175.2-59.7178.3000114.3E115 S123 R143E115-L125 HydrophobicContact CB-CB 4.39Å; E115-L125 HydrophobicContact CB-CD1 3.92Å; E115-L125 HydrophobicContact CB-CG 3.77Å; S123-L125 VanDerWaalsContact C-N 3.26Å; S123-L125 PolarHBondContact O-N 3.32Å; S123-L125 PolarHBondContact OG-N 2.98Å; L125-R143 HydrophobicContact CB-CG 4.09Å; L125-R143 PolarHBondContact O-NE 3.36Å; L125-R143 PolarHBondContact O-NH2 3.4Å
126L89.5Confident88.2Confident1 Ų170.2 Ų70.21%0.00535%0.353CS..SBendtrans-96.7132.2174.9-175.264000110.1S123 F130 R131 Q139 R143 F174S123-L126 PolarHBondContact OG-N 3.03Å; L126-F130 HydrophobicContact CD1-CB 3.8Å; L126-F130 HydrophobicContact CD1-CD2 4.46Å; L126-F130 HydrophobicContact CD1-CG 4.39Å; L126-F130 HydrophobicContact CD2-CB 4.18Å; L126-F130 HydrophobicContact CG-CB 3.9Å; L126-R131 HydrophobicContact CD2-CG 4.27Å; L126-R131 HydrophobicContact CG-CG 4.4Å; L126-R131 PolarHBondContact O-NE 2.78Å; L126-R131 PolarHBondContact O-NH2 3.41Å; L126-Q139 HydrophobicContact CD2-CB 3.78Å; L126-Q139 HydrophobicContact CD2-CG 4.07Å; L126-R143 HydrophobicContact CB-CB 4.43Å; L126-R143 HydrophobicContact CD1-CB 4.47Å; L126-F174 HydrophobicContact CD1-CD2 3.67Å; L126-F174 HydrophobicContact CD1-CE2 3.63Å; L126-F174 HydrophobicContact CD1-CG 4.18Å; L126-F174 HydrophobicContact CD1-CZ 4.09Å
127G87Confident88.5Confident35 Ų3573.7 Ų73.736%0.36137%0.369SS..  trans-61.1143179.500000113I129 F130G127-I129 VanDerWaalsContact C-N 3.26Å; G127-I129 PolarHBondContact O-N 2.98Å; G127-I129 VanDerWaalsContact O-N 3.14Å; G127-F130 PolarHBondContact O-N 2.96Å
128H87.8Confident89Confident109 Ų10971.8 Ų71.851%0.50536%0.356SS..G310 helixtrans-53.5-40.6-17163.7-65.9000113.6F130 R131 E210H128-F130 PolarHBondContact O-N 3.4Å; H128-R131 WeakPolarHBondContact O-CB 3.21Å; H128-R131 PolarHBondContact O-N 3.5Å; H128-R131 VanDerWaalsContact O-N 3.08Å; H128-E210 IonicContact CE1-OE1 2.74Å; H128-E210 PolarHBondContact CE1-OE1 2.88Å; H128-E210 IonicContact NE2-OE1 3.77Å; H128-E210 PolarHBondContact NE2-OE1 3.09Å
129I88.6Confident89.6Confident38 Ų3862.9 Ų62.920%0.19531%0.314CS..G310 helixtrans-57.3-30177.763.7-173.5000113.7G127 L203 T206 L207G127-I129 VanDerWaalsContact C-N 3.26Å; G127-I129 PolarHBondContact O-N 2.98Å; G127-I129 VanDerWaalsContact O-N 3.14Å; I129-L203 HydrophobicContact CB-CD1 3.61Å; I129-L203 HydrophobicContact CD1-CD1 3.97Å; I129-L203 HydrophobicContact CG1-CD1 3.89Å; I129-L203 HydrophobicContact CG2-CD1 4.49Å; I129-T206 HydrophobicContact CG2-CG2 4.18Å; I129-L207 HydrophobicContact CD1-CD2 3.68Å
130F91Very high90Very high24 Ų2459.8 Ų59.811%0.10530%0.298CS..G310 helixtrans-88.7-8.6179.8-59-71.4000113.6L126 G127 H128 V134 R173 F174 F177 L203L126-F130 HydrophobicContact CD1-CB 3.8Å; L126-F130 HydrophobicContact CD1-CD2 4.46Å; L126-F130 HydrophobicContact CD1-CG 4.39Å; L126-F130 HydrophobicContact CD2-CB 4.18Å; L126-F130 HydrophobicContact CG-CB 3.9Å; G127-F130 PolarHBondContact O-N 2.96Å; H128-F130 PolarHBondContact O-N 3.4Å; F130-V134 WeakPolarHBondContact O-CG2 3.37Å; F130-R173 HydrophobicContact CD1-CG 4.43Å; F130-R173 HydrophobicContact CE1-CG 4.48Å; F130-F174 HydrophobicContact CD1-CB 4.37Å; F130-F174 HydrophobicContact CD1-CD2 4.27Å; F130-F174 HydrophobicContact CD2-CD2 4.07Å; F130-F174 HydrophobicContact CE1-CD2 4.46Å; F130-F174 HydrophobicContact CE2-CD2 4.27Å; F130-F174 HydrophobicContact CG-CD2 4.08Å; F130-F174 HydrophobicContact CZ-CD2 4.47Å; F130-F177 HydrophobicContact CE1-CB 4.09Å; F130-F177 HydrophobicContact CZ-CB 4.15Å; F130-L203 HydrophobicContact CD1-CD2 4.21Å; F130-L203 HydrophobicContact CE1-CD2 3.78Å
131R91.6Very high90.6Very high53 Ų5353.3 Ų53.320%0.227%0.269CS..  trans-82.1-15.1179.7-53.6176.7-163.6161.4-0.1112.8S123 L126 H128 H133 V134S123-R131 PolarHBondContact O-NE 2.82Å; S123-R131 PolarHBondContact O-NH2 3.13Å; L126-R131 HydrophobicContact CD2-CG 4.27Å; L126-R131 HydrophobicContact CG-CG 4.4Å; L126-R131 PolarHBondContact O-NE 2.78Å; L126-R131 PolarHBondContact O-NH2 3.41Å; H128-R131 WeakPolarHBondContact O-CB 3.21Å; H128-R131 PolarHBondContact O-N 3.5Å; H128-R131 VanDerWaalsContact O-N 3.08Å; R131-H133 PolarHBondContact O-N 2.72Å; R131-V134 PolarHBondContact O-N 2.92Å; R131-V134 VanDerWaalsContact O-N 3.08Å
132K88.4Confident91.1Very high108 Ų10850.8 Ų50.847%0.4725%0.252SS..THydrogen-bonded Turntrans-64126.6-173.7-160.4-164.1-177.7-171.90111.2V134 H170K132-V134 PolarHBondContact O-N 2.82Å; K132-H170 PolarHBondContact O-CE1 3.18Å
133H89.1Confident91.5Very high100 Ų10051.4 Ų51.446%0.46325%0.251SS..THydrogen-bonded Turntrans647.1-173.7-48.1-74.4000115.6R131 H170 Y199R131-H133 PolarHBondContact O-N 2.72Å; H133-H170 VanDerWaalsContact CB-CE1 3.44Å; H133-H170 WeakPolarHBondContact CB-CE1 3.36Å; H133-Y199 HydrophobicContact CB-CE1 4.41Å; H133-Y199 AromaticContact CD2-CD1 3.64Å; H133-Y199 AromaticContact CD2-CE1 3.16Å; H133-Y199 WeakPolarHBondContact CD2-CE1 3.36Å; H133-Y199 AromaticContact CD2-CZ 3.71Å; H133-Y199 AromaticContact CG-CE1 3.71Å; H133-Y199 AromaticContact CG-CZ 3.77Å; H133-Y199 AromaticContact NE2-CE1 3.45Å; H133-Y199 WeakPolarHBondContact NE2-CE1 3.4Å
134V92.6Very high91.8Very high10 Ų1052.7 Ų52.76%0.06126%0.261CS..  trans-101.3119.5-179.7-169.30000110.7F130 R131 K132 K138 Q139 I142 H170F130-V134 WeakPolarHBondContact O-CG2 3.37Å; R131-V134 PolarHBondContact O-N 2.92Å; R131-V134 VanDerWaalsContact O-N 3.08Å; K132-V134 PolarHBondContact O-N 2.82Å; V134-K138 HydrophobicContact CG1-CB 3.76Å; V134-K138 HydrophobicContact CG1-CG 3.98Å; V134-Q139 HydrophobicContact CB-CG 3.84Å; V134-Q139 HydrophobicContact CG1-CB 4.35Å; V134-Q139 HydrophobicContact CG1-CG 3.57Å; V134-Q139 PolarHBondContact O-NE2 3.13Å; V134-I142 HydrophobicContact CG1-CD1 3.95Å; V134-H170 HydrophobicContact CG2-CB 4.37Å
135K93.7Very high92.3Very high172 Ų17249.6 Ų49.675%0.74824%0.239SC*.  trans-62.5149.1173.3-69.3-173.7179.4-178.30110.9K137 K138 Q139K135-K137 PolarHBondContact O-N 2.72Å; K135-K138 WeakPolarHBondContact O-CA 3.48Å; K135-K138 PolarHBondContact O-N 3.35Å; K135-Q139 PolarHBondContact O-N 3.24Å; K135-Q139 VanDerWaalsContact O-N 3.11Å
136P92.6Very high92.7Very high36 Ų3644.9 Ų44.923%0.23421%0.214CC..Hα-helixtrans-52.2-46.9-171.8-29.236.5000114.4F116 K138 Q139 H140 F593F116-P136 HydrophobicContact CD1-CB 4.37Å; F116-P136 HydrophobicContact CE1-CB 3.81Å; F116-P136 HydrophobicContact CZ-CB 4.3Å; F116-P136 VanDerWaalsContact CZ-O 3.3Å; F116-P136 WeakPolarHBondContact CZ-O 3.39Å; P136-K138 VanDerWaalsContact C-N 3.31Å; P136-K138 PolarHBondContact O-N 2.8Å; P136-Q139 WeakPolarHBondContact O-CB 3.37Å; P136-Q139 PolarHBondContact O-N 2.85Å; P136-H140 PolarHBondContact O-N 2.56Å; P136-F593 HydrophobicContact CB-CZ 3.86Å
137K92.7Very high93.1Very high76 Ų7646.8 Ų46.833%0.3323%0.226SC..Hα-helixtrans-51-46.9172.7172.5175.8173.4164.20113K135 Q139 H140 E141 F593 S594K135-K137 PolarHBondContact O-N 2.72Å; K137-Q139 VanDerWaalsContact C-N 3.32Å; K137-Q139 PolarHBondContact O-N 3.13Å; K137-H140 WeakPolarHBondContact O-CB 3.34Å; K137-H140 PolarHBondContact O-N 3.2Å; K137-E141 WeakPolarHBondContact CE-OE1 3.33Å; K137-E141 IonicContact NZ-OE1 3.15Å; K137-E141 WeakPolarHBondContact O-CG 3.34Å; K137-E141 PolarHBondContact O-N 2.8Å; K137-E141 VanDerWaalsContact O-N 3.1Å; K137-F593 HydrophobicContact CB-CE1 4.4Å; K137-F593 WeakPolarHBondContact CD-O 3.22Å; K137-F593 WeakPolarHBondContact CG-O 3.45Å; K137-S594 WeakPolarHBondContact CE-OG 3.39Å; K137-S594 PolarHBondContact NZ-OG 3.42Å
138K94.1Very high93.6Very high61 Ų6145.3 Ų45.327%0.26521%0.21SC..Hα-helixtrans-73.5-23-178.6-168.8162.5-176.7163.80112.3V134 K135 P136 I142V134-K138 HydrophobicContact CG1-CB 3.76Å; V134-K138 HydrophobicContact CG1-CG 3.98Å; K135-K138 WeakPolarHBondContact O-CA 3.48Å; K135-K138 PolarHBondContact O-N 3.35Å; P136-K138 VanDerWaalsContact C-N 3.31Å; P136-K138 PolarHBondContact O-N 2.8Å; K138-I142 HydrophobicContact CG-CD1 3.81Å; K138-I142 HydrophobicContact CG-CG1 4.2Å; K138-I142 WeakPolarHBondContact O-CB 3.37Å; K138-I142 VanDerWaalsContact O-CD1 3.32Å; K138-I142 WeakPolarHBondContact O-CD1 3.17Å; K138-I142 WeakPolarHBondContact O-CG1 3.47Å; K138-I142 PolarHBondContact O-N 3.46Å
139Q95.5Very high94Very high0 Ų040.1 Ų40.10%019%0.186CC..Hα-helixtrans-65.3-46.9170.9-60.7174.12600110.9F116 S121 L126 V134 K135 P136 K137 I142 R143F116-Q139 HydrophobicContact CZ-CB 4.5Å; S121-Q139 PolarHBondContact O-NE2 3.1Å; L126-Q139 HydrophobicContact CD2-CB 3.78Å; L126-Q139 HydrophobicContact CD2-CG 4.07Å; V134-Q139 HydrophobicContact CB-CG 3.84Å; V134-Q139 HydrophobicContact CG1-CB 4.35Å; V134-Q139 HydrophobicContact CG1-CG 3.57Å; V134-Q139 PolarHBondContact O-NE2 3.13Å; K135-Q139 PolarHBondContact O-N 3.24Å; K135-Q139 VanDerWaalsContact O-N 3.11Å; P136-Q139 WeakPolarHBondContact O-CB 3.37Å; P136-Q139 PolarHBondContact O-N 2.85Å; K137-Q139 VanDerWaalsContact C-N 3.32Å; K137-Q139 PolarHBondContact O-N 3.13Å; Q139-I142 PolarHBondContact O-N 3.12Å; Q139-R143 WeakPolarHBondContact O-CB 3.24Å; Q139-R143 PolarHBondContact O-N 3.41Å
140H94.1Very high94.4Very high12 Ų1240.5 Ų40.56%0.05619%0.186CC..Hα-helixtrans-58-50.8174.2175.775.5000111.5E115 F116 P136 K137 I142 R143 S144 F589 D590 F593E115-H140 IonicContact OE1-CE1 2.64Å; E115-H140 IonicContact OE1-CG 3.41Å; E115-H140 IonicContact OE1-ND1 3.18Å; E115-H140 PolarHBondContact OE1-ND1 2.94Å; F116-H140 HydrophobicContact CE2-CB 4.09Å; F116-H140 HydrophobicContact CZ-CB 4.26Å; P136-H140 PolarHBondContact O-N 2.56Å; K137-H140 WeakPolarHBondContact O-CB 3.34Å; K137-H140 PolarHBondContact O-N 3.2Å; H140-I142 PolarHBondContact O-N 3.5Å; H140-R143 PolarHBondContact O-N 3.07Å; H140-S144 WeakPolarHBondContact O-CB 3.36Å; H140-S144 PolarHBondContact O-N 3.12Å; H140-S144 PolarHBondContact O-OG 3.13Å; H140-F589 WeakPolarHBondContact NE2-CA 3.2Å; H140-D590 PolarHBondContact NE2-N 2.96Å; H140-F593 HydrophobicContact CB-CD1 4.01Å; H140-F593 HydrophobicContact CB-CE1 3.89Å
141E96.1Very high94.7Very high3 Ų343.3 Ų43.31%0.01420%0.199CC..Hα-helixtrans-59.2-46.3-179.9-68.8170.3158.700112.6K137 L145 L376 H377 F589 S594K137-E141 WeakPolarHBondContact CE-OE1 3.33Å; K137-E141 IonicContact NZ-OE1 3.15Å; K137-E141 WeakPolarHBondContact O-CG 3.34Å; K137-E141 PolarHBondContact O-N 2.8Å; K137-E141 VanDerWaalsContact O-N 3.1Å; E141-L145 WeakPolarHBondContact O-CB 3.25Å; E141-L145 PolarHBondContact O-N 3.37Å; E141-L376 HydrophobicContact CB-CD1 4.1Å; E141-L376 HydrophobicContact CB-CD2 4.27Å; E141-H377 IonicContact OE1-CE1 3.79Å; E141-H377 PolarHBondContact OE1-CE1 2.79Å; E141-H377 IonicContact OE1-NE2 2.97Å; E141-H377 PolarHBondContact OE1-NE2 2.88Å; E141-H377 IonicContact OE2-CD2 3.94Å; E141-H377 IonicContact OE2-CE1 2.85Å; E141-H377 IonicContact OE2-NE2 3.89Å; E141-H377 PolarHBondContact OE2-NE2 2.92Å; E141-F589 HydrophobicContact CB-CE1 4.18Å; E141-F589 HydrophobicContact CB-CE2 4.43Å; E141-F589 HydrophobicContact CB-CZ 4.06Å; E141-F589 HydrophobicContact CG-CD1 4.42Å; E141-F589 HydrophobicContact CG-CD2 4.1Å; E141-F589 HydrophobicContact CG-CE1 4.32Å; E141-F589 HydrophobicContact CG-CE2 3.99Å; E141-F589 HydrophobicContact CG-CG 4.33Å; E141-F589 HydrophobicContact CG-CZ 4.11Å; E141-S594 WeakPolarHBondContact OE1-CB 3.38Å; E141-S594 PolarHBondContact OE1-OG 2.82Å
142I96.6Very high94.8Very high2 Ų240.9 Ų40.91%0.0119%0.19CC..Hα-helixtrans-62.8-45.3177.8-72.9164.6000111.2V134 K138 Q139 H140 G146 H170 L171 F174 L376V134-I142 HydrophobicContact CG1-CD1 3.95Å; K138-I142 HydrophobicContact CG-CD1 3.81Å; K138-I142 HydrophobicContact CG-CG1 4.2Å; K138-I142 WeakPolarHBondContact O-CB 3.37Å; K138-I142 VanDerWaalsContact O-CD1 3.32Å; K138-I142 WeakPolarHBondContact O-CD1 3.17Å; K138-I142 WeakPolarHBondContact O-CG1 3.47Å; K138-I142 PolarHBondContact O-N 3.46Å; Q139-I142 PolarHBondContact O-N 3.12Å; H140-I142 PolarHBondContact O-N 3.5Å; I142-G146 WeakPolarHBondContact O-CA 3.35Å; I142-G146 PolarHBondContact O-N 2.88Å; I142-H170 HydrophobicContact CD1-CB 3.48Å; I142-H170 VanDerWaalsContact CD1-CB 3.48Å; I142-L171 HydrophobicContact CG1-CB 4.34Å; I142-L171 HydrophobicContact CG2-CD1 4.29Å; I142-F174 HydrophobicContact CG2-CB 3.6Å; I142-F174 HydrophobicContact CG2-CD1 3.51Å; I142-F174 HydrophobicContact CG2-CE1 4.42Å; I142-F174 HydrophobicContact CG2-CG 3.71Å; I142-L376 HydrophobicContact CG1-CD2 4Å
143R95.8Very high95.2Very high75 Ų7535.7 Ų35.728%0.28317%0.168SC..Hα-helixtrans-65-50.1-178.7-179.349.8163.31012.9111.1L125 L126 Q139 H140 T147L125-R143 HydrophobicContact CB-CG 4.09Å; L125-R143 PolarHBondContact O-NE 3.36Å; L125-R143 PolarHBondContact O-NH2 3.4Å; L126-R143 HydrophobicContact CB-CB 4.43Å; L126-R143 HydrophobicContact CD1-CB 4.47Å; Q139-R143 WeakPolarHBondContact O-CB 3.24Å; Q139-R143 PolarHBondContact O-N 3.41Å; H140-R143 PolarHBondContact O-N 3.07Å; R143-T147 PolarHBondContact NH1-OG1 3.48Å; R143-T147 WeakPolarHBondContact O-CB 3.36Å; R143-T147 PolarHBondContact O-N 3.02Å; R143-T147 VanDerWaalsContact O-N 3.16Å; R143-T147 PolarHBondContact O-OG1 3.44Å
144S95.7Very high95.4Very high28 Ų2835.7 Ų35.720%0.19617%0.171CC..Hα-helixtrans-66.8-46.8-177.9-60.10000111.9H140 T147 L148H140-S144 WeakPolarHBondContact O-CB 3.36Å; H140-S144 PolarHBondContact O-N 3.12Å; H140-S144 PolarHBondContact O-OG 3.13Å; S144-T147 PolarHBondContact O-N 3.37Å; S144-L148 PolarHBondContact O-N 2.87Å
145L97.6Very high95.4Very high0 Ų041.4 Ų41.40%020%0.201CC..Hα-helixtrans-70.5-41.8179.4-175.762.3000112.7E141 T147 L148 V149 L171 L376 T400 V402 L588 F589 V599E141-L145 WeakPolarHBondContact O-CB 3.25Å; E141-L145 PolarHBondContact O-N 3.37Å; L145-T147 PolarHBondContact O-N 3.38Å; L145-L148 WeakPolarHBondContact O-CB 3.34Å; L145-L148 PolarHBondContact O-N 3.31Å; L145-V149 HydrophobicContact CD1-CG2 4.31Å; L145-V149 HydrophobicContact CG-CG2 4.26Å; L145-V149 WeakPolarHBondContact O-CG2 3.47Å; L145-V149 PolarHBondContact O-N 3.23Å; L145-L171 HydrophobicContact CD2-CD2 3.79Å; L145-L171 HydrophobicContact CG-CD2 4.37Å; L145-L376 HydrophobicContact CD2-CB 3.76Å; L145-L376 HydrophobicContact CD2-CD1 3.89Å; L145-L376 HydrophobicContact CD2-CD2 4.45Å; L145-L376 HydrophobicContact CD2-CG 4.21Å; L145-T400 HydrophobicContact CD1-CG2 4.45Å; L145-V402 HydrophobicContact CD1-CG2 4.34Å; L145-V402 HydrophobicContact CD2-CG2 3.78Å; L145-L588 HydrophobicContact CB-CD2 4.22Å; L145-L588 HydrophobicContact CD1-CD2 4.07Å; L145-F589 HydrophobicContact CB-CE1 4.21Å; L145-F589 HydrophobicContact CB-CZ 4.25Å; L145-V599 HydrophobicContact CD1-CG1 4.08Å
146G97.6Very high95.3Very high0 Ų035.1 Ų35.10%018%0.177CC..Hα-helixtrans-59.9-37.1177.100000112.4I142 V149 K150 L179I142-G146 WeakPolarHBondContact O-CA 3.35Å; I142-G146 PolarHBondContact O-N 2.88Å; G146-V149 PolarHBondContact O-N 3.47Å; G146-K150 PolarHBondContact O-N 3.11Å; G146-L179 VanDerWaalsContact C-CD1 3.48Å; G146-L179 WeakPolarHBondContact O-CD1 3.39Å
147T96.8Very high95.3Very high40 Ų4040.1 Ų40.125%0.24520%0.201CC..Hα-helixtrans-64-42.1173.4-49.50000111.6R143 S144 L145 K150 Q151R143-T147 PolarHBondContact NH1-OG1 3.48Å; R143-T147 WeakPolarHBondContact O-CB 3.36Å; R143-T147 PolarHBondContact O-N 3.02Å; R143-T147 VanDerWaalsContact O-N 3.16Å; R143-T147 PolarHBondContact O-OG1 3.44Å; S144-T147 PolarHBondContact O-N 3.37Å; L145-T147 PolarHBondContact O-N 3.38Å; T147-K150 PolarHBondContact O-N 2.9Å; T147-Q151 WeakPolarHBondContact O-CG 3.29Å; T147-Q151 PolarHBondContact O-N 2.89Å; T147-Q151 VanDerWaalsContact O-N 3.09Å
148L96.9Very high95.3Very high4 Ų436.9 Ų36.92%0.02119%0.188CC..Hα-helixtrans-66.5-43.8177.6-165.669000111.7M1 S144 L145 K150 Q151 L152 T400 L588 V599 M601M1-L148 HydrophobicContact CE-CD1 3.84Å; S144-L148 PolarHBondContact O-N 2.87Å; L145-L148 WeakPolarHBondContact O-CB 3.34Å; L145-L148 PolarHBondContact O-N 3.31Å; L148-K150 PolarHBondContact O-N 3.45Å; L148-Q151 WeakPolarHBondContact O-CB 3.25Å; L148-Q151 PolarHBondContact O-N 3.36Å; L148-Q151 VanDerWaalsContact O-N 3.16Å; L148-L152 HydrophobicContact CG-CD1 4.22Å; L148-L152 WeakPolarHBondContact O-CD1 3.34Å; L148-L152 PolarHBondContact O-N 3.46Å; L148-T400 HydrophobicContact CD2-CG2 4.08Å; L148-T400 HydrophobicContact CG-CG2 4.41Å; L148-L588 HydrophobicContact CB-CD1 4.44Å; L148-L588 HydrophobicContact CB-CD2 4.17Å; L148-L588 HydrophobicContact CD2-CD1 4.24Å; L148-L588 HydrophobicContact CD2-CD2 3.75Å; L148-V599 HydrophobicContact CD2-CG1 4.34Å; L148-M601 HydrophobicContact CD1-CE 3.58Å; L148-M601 HydrophobicContact CD2-CE 3.84Å; L148-M601 HydrophobicContact CG-CE 3.83Å
149V98Very high95.2Very high0 Ų037.4 Ų37.40%019%0.194CC..Hα-helixtrans-59-46.6175.4172.40000110.6L145 G146 Q151 L152 C153 V161 L175 I372 T374 T400L145-V149 HydrophobicContact CD1-CG2 4.31Å; L145-V149 HydrophobicContact CG-CG2 4.26Å; L145-V149 WeakPolarHBondContact O-CG2 3.47Å; L145-V149 PolarHBondContact O-N 3.23Å; G146-V149 PolarHBondContact O-N 3.47Å; V149-Q151 VanDerWaalsContact C-N 3.29Å; V149-Q151 PolarHBondContact O-N 2.93Å; V149-L152 WeakPolarHBondContact O-CA 3.25Å; V149-L152 WeakPolarHBondContact O-CB 3.43Å; V149-L152 PolarHBondContact O-N 3.02Å; V149-C153 PolarHBondContact O-N 3.18Å; V149-C153 PolarHBondContact O-SG 3.08Å; V149-V161 HydrophobicContact CG1-CG1 4Å; V149-V161 HydrophobicContact CG1-CG2 3.95Å; V149-L175 HydrophobicContact CB-CD2 3.81Å; V149-L175 HydrophobicContact CG1-CD1 4.44Å; V149-L175 HydrophobicContact CG1-CD2 3.65Å; V149-L175 HydrophobicContact CG2-CD2 4.49Å; V149-I372 HydrophobicContact CG1-CG2 4.46Å; V149-T374 HydrophobicContact CG2-CG2 4.48Å; V149-T400 WeakPolarHBondContact CG2-OG1 3.4Å
150K97.1Very high95.3Very high47 Ų4738.9 Ų38.920%0.20420%0.204CC..Hα-helixtrans-60.8-38.2176.2-178.954178.5151.70112G146 T147 L148 L152 C153 D154 N159 L179 L181G146-K150 PolarHBondContact O-N 3.11Å; T147-K150 PolarHBondContact O-N 2.9Å; L148-K150 PolarHBondContact O-N 3.45Å; K150-L152 VanDerWaalsContact C-N 3.34Å; K150-L152 PolarHBondContact O-N 2.89Å; K150-C153 HydrophobicContact CD-CB 4.36Å; K150-C153 WeakPolarHBondContact O-CB 3.45Å; K150-C153 PolarHBondContact O-N 3.47Å; K150-D154 WeakPolarHBondContact CE-OD1 3.44Å; K150-D154 IonicContact NZ-OD1 3.22Å; K150-D154 PolarHBondContact NZ-OD1 3.13Å; K150-D154 PolarHBondContact O-N 3.04Å; K150-N159 PolarHBondContact NZ-OD1 2.81Å; K150-L179 HydrophobicContact CB-CD1 4.06Å; K150-L181 HydrophobicContact CB-CD1 4.4Å; K150-L181 HydrophobicContact CD-CD1 4.16Å; K150-L181 HydrophobicContact CD-CD2 3.85Å; K150-L181 HydrophobicContact CD-CG 4.16Å
151Q95.8Very high95.4Very high82 Ų8238.3 Ų38.338%0.38320%0.202SC..Hα-helixtrans-63.9-34172.3-71.2173.7-1.800113.2T147 L148 V149 L155T147-Q151 WeakPolarHBondContact O-CG 3.29Å; T147-Q151 PolarHBondContact O-N 2.89Å; T147-Q151 VanDerWaalsContact O-N 3.09Å; L148-Q151 WeakPolarHBondContact O-CB 3.25Å; L148-Q151 PolarHBondContact O-N 3.36Å; L148-Q151 VanDerWaalsContact O-N 3.16Å; V149-Q151 VanDerWaalsContact C-N 3.29Å; V149-Q151 PolarHBondContact O-N 2.93Å; Q151-L155 WeakPolarHBondContact O-CB 3.5Å; Q151-L155 WeakPolarHBondContact O-CD1 3.36Å; Q151-L155 WeakPolarHBondContact O-CG 3.27Å; Q151-L155 PolarHBondContact O-N 2.68Å; Q151-L155 VanDerWaalsContact O-N 3.09Å
152L95Very high95.5Very high2 Ų238.2 Ų38.21%0.0120%0.201CC..Hα-helixtrans-65.4-45.1170-87.679.1000111.4L148 V149 K150 D154 L155 T156 I372 T400 M601 L603L148-L152 HydrophobicContact CG-CD1 4.22Å; L148-L152 WeakPolarHBondContact O-CD1 3.34Å; L148-L152 PolarHBondContact O-N 3.46Å; V149-L152 WeakPolarHBondContact O-CA 3.25Å; V149-L152 WeakPolarHBondContact O-CB 3.43Å; V149-L152 PolarHBondContact O-N 3.02Å; K150-L152 VanDerWaalsContact C-N 3.34Å; K150-L152 PolarHBondContact O-N 2.89Å; L152-D154 VanDerWaalsContact C-N 3.32Å; L152-D154 PolarHBondContact O-N 3.3Å; L152-L155 PolarHBondContact O-N 3.2Å; L152-T156 PolarHBondContact O-N 3.36Å; L152-T156 PolarHBondContact O-OG1 2.96Å; L152-I372 HydrophobicContact CB-CD1 4.27Å; L152-I372 HydrophobicContact CB-CG1 4.46Å; L152-I372 HydrophobicContact CB-CG2 4.35Å; L152-I372 HydrophobicContact CD2-CG2 4.14Å; L152-T400 HydrophobicContact CD1-CG2 3.81Å; L152-T400 HydrophobicContact CD2-CG2 3.92Å; L152-M601 HydrophobicContact CD1-CE 3.86Å; L152-M601 HydrophobicContact CD1-CG 4.05Å; L152-M601 HydrophobicContact CD1-SD 3.93Å; L152-M601 HydrophobicContact CD2-CG 4.16Å; L152-M601 HydrophobicContact CG-CG 4.44Å; L152-M601 HydrophobicContact CG-SD 4.48Å; L152-L603 HydrophobicContact CD2-CD2 3.84Å; L152-L603 HydrophobicContact CG-CD2 4.01Å
153C95.6Very high95.6Very high0 Ų038.2 Ų38.20%020%0.201CC..Hα-helixtrans-56-48.2176.5-57.50000110.9V149 K150 L155 T156 D157 C158 L181V149-C153 PolarHBondContact O-N 3.18Å; V149-C153 PolarHBondContact O-SG 3.08Å; K150-C153 HydrophobicContact CD-CB 4.36Å; K150-C153 WeakPolarHBondContact O-CB 3.45Å; K150-C153 PolarHBondContact O-N 3.47Å; C153-L155 VanDerWaalsContact C-N 3.31Å; C153-L155 PolarHBondContact O-N 3.26Å; C153-T156 CarbonylContact O-C 3.43Å; C153-T156 PolarHBondContact O-N 2.85Å; C153-T156 VanDerWaalsContact O-N 3.16Å; C153-T156 PolarHBondContact O-OG1 3.02Å; C153-D157 WeakPolarHBondContact O-CA 3.14Å; C153-D157 PolarHBondContact O-N 2.84Å; C153-C158 WeakPolarHBondContact CA-O 3.34Å; C153-C158 WeakPolarHBondContact CB-O 3.45Å; C153-C158 PolarHBondContact O-N 3.24Å; C153-C158 PolarHBondContact SG-O 3.49Å; C153-C158 VanDerWaalsContact SG-O 3.33Å; C153-L181 HydrophobicContact CB-CD2 3.96Å
154D94.7Very high95.7Very high99 Ų9934.8 Ų34.853%0.52919%0.189SC..Hα-helixtrans-65.5-31.3179.6-62-26.5000112.8K150 L152 T156K150-D154 WeakPolarHBondContact CE-OD1 3.44Å; K150-D154 IonicContact NZ-OD1 3.22Å; K150-D154 PolarHBondContact NZ-OD1 3.13Å; K150-D154 PolarHBondContact O-N 3.04Å; L152-D154 VanDerWaalsContact C-N 3.32Å; L152-D154 PolarHBondContact O-N 3.3Å; D154-T156 VanDerWaalsContact C-N 3.31Å
155L92.5Very high95.7Very high131 Ų13134.6 Ų34.669%0.68619%0.191SC*.Hα-helixtrans-80.1-7.4176-74.6170.7000114.3Q151 L152 C153Q151-L155 WeakPolarHBondContact O-CB 3.5Å; Q151-L155 WeakPolarHBondContact O-CD1 3.36Å; Q151-L155 WeakPolarHBondContact O-CG 3.27Å; Q151-L155 PolarHBondContact O-N 2.68Å; Q151-L155 VanDerWaalsContact O-N 3.09Å; L152-L155 PolarHBondContact O-N 3.2Å; C153-L155 VanDerWaalsContact C-N 3.31Å; C153-L155 PolarHBondContact O-N 3.26Å
156T91.4Very high95.6Very high39 Ų3934.9 Ų34.924%0.23919%0.193CC..Hα-helixtrans-128.93.4-175.352.70000113.6L152 C153 D154 C158 I372 R397 L603L152-T156 PolarHBondContact O-N 3.36Å; L152-T156 PolarHBondContact O-OG1 2.96Å; C153-T156 CarbonylContact O-C 3.43Å; C153-T156 PolarHBondContact O-N 2.85Å; C153-T156 VanDerWaalsContact O-N 3.16Å; C153-T156 PolarHBondContact O-OG1 3.02Å; D154-T156 VanDerWaalsContact C-N 3.31Å; T156-C158 PolarHBondContact O-N 3.31Å; T156-C158 VanDerWaalsContact O-N 3.12Å; T156-C158 WeakPolarHBondContact OG1-CB 3.32Å; T156-I372 HydrophobicContact CG2-CD1 4.43Å; T156-R397 HydrophobicContact CG2-CB 4.29Å; T156-L603 HydrophobicContact CG2-CD2 3.89Å
157D91.6Very high95.5Very high141 Ų14135.4 Ų35.475%0.75420%0.198SC*.THydrogen-bonded Turntrans48.925.5-167-154.216.9000114.4C153C153-D157 WeakPolarHBondContact O-CA 3.14Å; C153-D157 PolarHBondContact O-N 2.84Å
158C91.9Very high95.4Very high8 Ų836.2 Ų36.25%0.05420%0.199CC..  trans-107.292.6-166.9-173.70000110.4C153 T156 S160 D370 F371 I372 R397C153-C158 WeakPolarHBondContact CA-O 3.34Å; C153-C158 WeakPolarHBondContact CB-O 3.45Å; C153-C158 PolarHBondContact O-N 3.24Å; C153-C158 PolarHBondContact SG-O 3.49Å; C153-C158 VanDerWaalsContact SG-O 3.33Å; T156-C158 PolarHBondContact O-N 3.31Å; T156-C158 VanDerWaalsContact O-N 3.12Å; T156-C158 WeakPolarHBondContact OG1-CB 3.32Å; C158-S160 VanDerWaalsContact C-N 3.28Å; C158-S160 PolarHBondContact O-N 3.19Å; C158-D370 PolarHBondContact SG-O 3.43Å; C158-F371 VanDerWaalsContact SG-C 3.55Å; C158-F371 WeakPolarHBondContact SG-CA 3.2Å; C158-F371 PolarHBondContact SG-N 3.15Å; C158-F371 VanDerWaalsContact SG-N 3.43Å; C158-I372 HydrophobicContact CB-CD1 4.4Å; C158-I372 HydrophobicContact CB-CG1 4.32Å; C158-R397 HydrophobicContact CB-CG 4.35Å
159N93.6Very high95.4Very high72 Ų7236 Ų3639%0.38520%0.198SC..  trans-85.99.1-175.6-70.2-79.1000114.5K150 L181 S182K150-N159 PolarHBondContact NZ-OD1 2.81Å; N159-L181 HydrophobicContact CB-CD2 4.21Å; N159-S182 PolarHBondContact O-N 3.36Å
160S96Very high95.4Very high31 Ų3136.7 Ų36.722%0.21720%0.202CC..EExtended strand (participates in β ladder)trans-102.7136.2176.5-172.70000111.1C158 S182 D370 F371 I372C158-S160 VanDerWaalsContact C-N 3.28Å; C158-S160 PolarHBondContact O-N 3.19Å; S160-S182 CarbonylContact C-O 3.01Å; S160-S182 WeakPolarHBondContact CA-O 3.14Å; S160-D370 WeakPolarHBondContact CB-O 3.39Å; S160-F371 WeakPolarHBondContact O-CA 3.49Å; S160-I372 PolarHBondContact O-N 3.11Å
161V97.9Very high95.4Very high0 Ų034.7 Ų34.70%019%0.193CC..EExtended strand (participates in β ladder)trans-135.7137.4-178-174.60000111.7V149 L175 L181 S182 V183 T184 I372 T374V149-V161 HydrophobicContact CG1-CG1 4Å; V149-V161 HydrophobicContact CG1-CG2 3.95Å; V161-L175 HydrophobicContact CG1-CD1 4.05Å; V161-L181 HydrophobicContact CG2-CB 4.44Å; V161-L181 HydrophobicContact CG2-CD1 4Å; V161-S182 PolarHBondContact N-O 3.15Å; V161-V183 HydrophobicContact CB-CG1 4.18Å; V161-V183 HydrophobicContact CB-CG2 4.46Å; V161-V183 HydrophobicContact CG1-CG1 4.44Å; V161-V183 VanDerWaalsContact O-CA 3.31Å; V161-V183 WeakPolarHBondContact O-CA 3.5Å; V161-T184 PolarHBondContact O-N 2.99Å; V161-I372 CarbonylContact C-O 3.44Å; V161-I372 VanDerWaalsContact CA-O 3.29Å; V161-I372 WeakPolarHBondContact CA-O 2.87Å; V161-I372 HydrophobicContact CG2-CB 4.38Å; V161-T374 HydrophobicContact CG1-CG2 3.7Å
162V98.1Very high95.5Very high1 Ų130.8 Ų30.81%0.00618%0.175CC..EExtended strand (participates in β ladder)trans-112.1117.7170.8179.20000109.4V164 T184 I186 F242 V246 F371 I372 L373 T374V162-V164 HydrophobicContact CG1-CG2 3.76Å; V162-T184 CarbonylContact C-O 3.48Å; V162-T184 WeakPolarHBondContact CA-O 3.41Å; V162-I186 HydrophobicContact CG1-CD1 3.85Å; V162-I186 HydrophobicContact CG1-CG1 4.28Å; V162-F242 HydrophobicContact CG1-CZ 4.41Å; V162-V246 HydrophobicContact CG1-CG2 4.01Å; V162-V246 HydrophobicContact CG2-CG1 3.72Å; V162-V246 HydrophobicContact CG2-CG2 3.91Å; V162-F371 HydrophobicContact CB-CD2 3.85Å; V162-F371 HydrophobicContact CB-CE2 3.95Å; V162-F371 HydrophobicContact CG2-CB 4.5Å; V162-F371 HydrophobicContact CG2-CD2 3.37Å; V162-F371 HydrophobicContact CG2-CE2 3.56Å; V162-F371 HydrophobicContact CG2-CG 4.01Å; V162-F371 HydrophobicContact CG2-CZ 4.36Å; V162-I372 PolarHBondContact N-O 3.45Å; V162-L373 HydrophobicContact CB-CD1 4.07Å; V162-L373 HydrophobicContact CG1-CD1 4.05Å; V162-T374 PolarHBondContact O-N 3.02Å
163D98.3Very high95.6Very high2 Ų231.2 Ų31.21%0.01118%0.176CC..EExtended strand (participates in β ladder)trans-106.9100.8-175.7-17929.3000109.8S166 T172 V183 T184 G185 I186 T374D163-S166 WeakPolarHBondContact O-CB 3.31Å; D163-T172 HydrophobicContact CB-CG2 4.3Å; D163-T172 WeakPolarHBondContact OD2-CB 3.33Å; D163-T172 PolarHBondContact OD2-N 3.15Å; D163-T172 PolarHBondContact OD2-OG1 2.89Å; D163-V183 HydrophobicContact CB-CG1 4.4Å; D163-T184 PolarHBondContact N-O 3.4Å; D163-G185 CarbonylContact O-C 3.36Å; D163-G185 VanDerWaalsContact O-CA 3.29Å; D163-G185 WeakPolarHBondContact O-CA 3.29Å; D163-I186 PolarHBondContact O-N 2.67Å; D163-T374 HydrophobicContact CB-CG2 3.85Å
164V97.4Very high95.6Very high4 Ų431.7 Ų31.72%0.02418%0.178CC..EExtended strand (participates in β ladder)trans-102.4131.3-170-170.20000111.5V162 I186 V233 L373 T374 L382 L386V162-V164 HydrophobicContact CG1-CG2 3.76Å; V164-I186 HydrophobicContact CG1-CB 4.34Å; V164-I186 HydrophobicContact CG2-CB 4.45Å; V164-I186 HydrophobicContact CG2-CD1 4.43Å; V164-V233 HydrophobicContact CG1-CB 4.37Å; V164-V233 HydrophobicContact CG1-CG2 3.62Å; V164-L373 HydrophobicContact CG2-CD1 3.75Å; V164-T374 PolarHBondContact N-O 2.81Å; V164-L382 HydrophobicContact CG1-CD1 3.88Å; V164-L386 HydrophobicContact CB-CD2 3.62Å; V164-L386 HydrophobicContact CG1-CD2 3.99Å; V164-L386 HydrophobicContact CG2-CD2 3.65Å
165G95.5Very high95.8Very high23 Ų2327 Ų2724%0.23715%0.153CC..THydrogen-bonded Turntrans76.133.7-163.700000111.3G167 I186G165-G167 PolarHBondContact O-N 2.79Å; G165-I186 PolarHBondContact N-O 2.83Å
166S95.3Very high96Very high6 Ų620.8 Ų20.84%0.04212%0.12CC..  trans-63.8-21.4-173.961.90000113.5D163 Q168 G169 T172 I186D163-S166 WeakPolarHBondContact O-CB 3.31Å; S166-Q168 PolarHBondContact O-N 2.85Å; S166-G169 PolarHBondContact O-N 2.9Å; S166-T172 WeakPolarHBondContact CB-OG1 3.27Å; S166-I186 PolarHBondContact N-O 3.2Å
167G95.2Very high96.1Very high11 Ų1119.9 Ų19.911%0.11311%0.113CC..THydrogen-bonded Turntrans55.6-120.3-174.900000111.5G165 G169 E187 L192G165-G167 PolarHBondContact O-N 2.79Å; G167-G169 PolarHBondContact O-N 3.04Å; G167-E187 WeakPolarHBondContact CA-OE2 3.47Å; G167-E187 PolarHBondContact N-OE2 3.3Å; G167-L192 CarbonylContact O-C 3.52Å
168Q96.1Very high96.2Very high58 Ų5814.7 Ų14.727%0.2719%0.094SC..THydrogen-bonded Turntrans-7619.8177.4-60.7175.7-1000113.8S166 H170 R173 L192 M195 Y199S166-Q168 PolarHBondContact O-N 2.85Å; Q168-H170 VanDerWaalsContact C-N 3.28Å; Q168-H170 WeakPolarHBondContact CB-NE2 3.47Å; Q168-H170 PolarHBondContact O-N 2.7Å; Q168-H170 PolarHBondContact OE1-NE2 2.8Å; Q168-R173 PolarHBondContact O-NH1 3.09Å; Q168-R173 PolarHBondContact O-NH2 3.03Å; Q168-R173 VanDerWaalsContact O-NH2 3.14Å; Q168-L192 HydrophobicContact CG-CD2 3.97Å; Q168-M195 HydrophobicContact CG-CB 4.46Å; Q168-Y199 HydrophobicContact CB-CD2 4.28Å; Q168-Y199 HydrophobicContact CB-CE2 4.15Å; Q168-Y199 HydrophobicContact CG-CE2 4.38Å
169G96.6Very high96.3Very high0 Ų016.6 Ų16.60%010%0.103CC..THydrogen-bonded Turntrans63.421.1174.500000115.8S166 G167 T172 R173S166-G169 PolarHBondContact O-N 2.9Å; G167-G169 PolarHBondContact O-N 3.04Å; G169-T172 VanDerWaalsContact CA-OG1 3.27Å; G169-T172 WeakPolarHBondContact CA-OG1 3.47Å; G169-T172 WeakPolarHBondContact O-CB 3.42Å; G169-T172 PolarHBondContact O-N 3.4Å; G169-T172 PolarHBondContact O-OG1 2.93Å; G169-R173 WeakPolarHBondContact O-CB 3.44Å; G169-R173 PolarHBondContact O-N 3.47Å
170H97.2Very high96.3Very high14 Ų1415 Ų157%0.06510%0.104CC..Hα-helixtrans-70.2-33.4-170.4-67.4-65.5000113.9K132 H133 V134 I142 Q168 R173 F174 Y199K132-H170 PolarHBondContact O-CE1 3.18Å; H133-H170 VanDerWaalsContact CB-CE1 3.44Å; H133-H170 WeakPolarHBondContact CB-CE1 3.36Å; V134-H170 HydrophobicContact CG2-CB 4.37Å; I142-H170 HydrophobicContact CD1-CB 3.48Å; I142-H170 VanDerWaalsContact CD1-CB 3.48Å; Q168-H170 VanDerWaalsContact C-N 3.28Å; Q168-H170 WeakPolarHBondContact CB-NE2 3.47Å; Q168-H170 PolarHBondContact O-N 2.7Å; Q168-H170 PolarHBondContact OE1-NE2 2.8Å; H170-R173 PolarHBondContact ND1-NH1 3.21Å; H170-F174 PolarHBondContact O-N 2.91Å; H170-Y199 AromaticContact CE1-CD2 3.42Å; H170-Y199 VanDerWaalsContact CE1-CD2 3.42Å; H170-Y199 WeakPolarHBondContact CE1-CD2 3.45Å; H170-Y199 AromaticContact CE1-CE2 3.5Å; H170-Y199 VanDerWaalsContact CE1-CE2 3.5Å; H170-Y199 WeakPolarHBondContact CE1-CE2 3.21Å; H170-Y199 AromaticContact NE2-CE2 3.85Å
171L97.6Very high96.3Very high4 Ų413.6 Ų13.62%0.0219%0.094CC..Hα-helixtrans-74.1-51.2171.2175.760.4000110I142 L145 R173 F174 L175 T374 L376I142-L171 HydrophobicContact CG1-CB 4.34Å; I142-L171 HydrophobicContact CG2-CD1 4.29Å; L145-L171 HydrophobicContact CD2-CD2 3.79Å; L145-L171 HydrophobicContact CG-CD2 4.37Å; L171-R173 VanDerWaalsContact C-N 3.27Å; L171-R173 PolarHBondContact O-N 2.75Å; L171-F174 WeakPolarHBondContact O-CA 3.44Å; L171-F174 PolarHBondContact O-N 2.83Å; L171-L175 HydrophobicContact CD1-CD1 4.14Å; L171-L175 HydrophobicContact CD1-CD2 4.39Å; L171-L175 HydrophobicContact CD1-CG 3.97Å; L171-L175 HydrophobicContact CD2-CD1 4.41Å; L171-L175 HydrophobicContact CG-CD1 3.8Å; L171-L175 HydrophobicContact CG-CG 4.13Å; L171-L175 WeakPolarHBondContact O-CG 3.42Å; L171-L175 PolarHBondContact O-N 2.68Å; L171-T374 HydrophobicContact CD2-CG2 4.38Å; L171-L376 HydrophobicContact CB-CD2 4.27Å; L171-L376 HydrophobicContact CD2-CB 3.8Å; L171-L376 HydrophobicContact CD2-CD2 4.19Å
172T97.7Very high96.2Very high0 Ų016.6 Ų16.60%012%0.115CC..Hα-helixtrans-41.3-51.8173.1-210000112.7D163 S166 G169 F174 L175 S176 V183 P226D163-T172 HydrophobicContact CB-CG2 4.3Å; D163-T172 WeakPolarHBondContact OD2-CB 3.33Å; D163-T172 PolarHBondContact OD2-N 3.15Å; D163-T172 PolarHBondContact OD2-OG1 2.89Å; S166-T172 WeakPolarHBondContact CB-OG1 3.27Å; G169-T172 VanDerWaalsContact CA-OG1 3.27Å; G169-T172 WeakPolarHBondContact CA-OG1 3.47Å; G169-T172 WeakPolarHBondContact O-CB 3.42Å; G169-T172 PolarHBondContact O-N 3.4Å; G169-T172 PolarHBondContact O-OG1 2.93Å; T172-F174 PolarHBondContact O-N 3.33Å; T172-L175 PolarHBondContact O-N 3.04Å; T172-S176 PolarHBondContact O-N 2.94Å; T172-V183 HydrophobicContact CG2-CB 4.13Å; T172-V183 HydrophobicContact CG2-CG1 3.46Å; T172-V183 VanDerWaalsContact CG2-CG1 3.46Å; T172-P226 HydrophobicContact CG2-CB 3.98Å
173R96.9Very high96.2Very high11 Ų1116.7 Ų16.74%0.04212%0.115CC..Hα-helixtrans-63.9-36.8178.7-179.9-177.4-62.6102.232.2113.8F130 Q168 G169 H170 L171 F177 A196 D200 L203F130-R173 HydrophobicContact CD1-CG 4.43Å; F130-R173 HydrophobicContact CE1-CG 4.48Å; Q168-R173 PolarHBondContact O-NH1 3.09Å; Q168-R173 PolarHBondContact O-NH2 3.03Å; Q168-R173 VanDerWaalsContact O-NH2 3.14Å; G169-R173 WeakPolarHBondContact O-CB 3.44Å; G169-R173 PolarHBondContact O-N 3.47Å; H170-R173 PolarHBondContact ND1-NH1 3.21Å; L171-R173 VanDerWaalsContact C-N 3.27Å; L171-R173 PolarHBondContact O-N 2.75Å; R173-F177 HydrophobicContact CG-CD2 3.98Å; R173-F177 HydrophobicContact CG-CE2 4.41Å; R173-F177 PolarHBondContact O-N 3.27Å; R173-A196 PolarHBondContact NH2-O 2.84Å; R173-D200 WeakPolarHBondContact CG-OD1 3.37Å; R173-D200 IonicContact CZ-OD1 3.27Å; R173-D200 IonicContact NE-OD1 2.85Å; R173-D200 PolarHBondContact NE-OD1 3.09Å; R173-D200 IonicContact NH2-OD1 3.82Å; R173-D200 PolarHBondContact NH2-OD1 2.68Å; R173-D200 IonicContact NH2-OD2 4Å; R173-L203 HydrophobicContact CG-CD2 3.49Å; R173-L203 VanDerWaalsContact CG-CD2 3.49Å
174F97.2Very high96.1Very high11 Ų1117.4 Ų17.45%0.04812%0.12CC..Hα-helixtrans-75.3-40.1176.4177.1-118.9000111.7L126 F130 I142 H170 L171 T172 G178 L179L126-F174 HydrophobicContact CD1-CD2 3.67Å; L126-F174 HydrophobicContact CD1-CE2 3.63Å; L126-F174 HydrophobicContact CD1-CG 4.18Å; L126-F174 HydrophobicContact CD1-CZ 4.09Å; F130-F174 HydrophobicContact CD1-CB 4.37Å; F130-F174 HydrophobicContact CD1-CD2 4.27Å; F130-F174 HydrophobicContact CD2-CD2 4.07Å; F130-F174 HydrophobicContact CE1-CD2 4.46Å; F130-F174 HydrophobicContact CE2-CD2 4.27Å; F130-F174 HydrophobicContact CG-CD2 4.08Å; F130-F174 HydrophobicContact CZ-CD2 4.47Å; I142-F174 HydrophobicContact CG2-CB 3.6Å; I142-F174 HydrophobicContact CG2-CD1 3.51Å; I142-F174 HydrophobicContact CG2-CE1 4.42Å; I142-F174 HydrophobicContact CG2-CG 3.71Å; H170-F174 PolarHBondContact O-N 2.91Å; L171-F174 WeakPolarHBondContact O-CA 3.44Å; L171-F174 PolarHBondContact O-N 2.83Å; T172-F174 PolarHBondContact O-N 3.33Å; F174-G178 CarbonylContact O-C 3.58Å; F174-G178 WeakPolarHBondContact O-CA 3.1Å; F174-G178 PolarHBondContact O-N 3.38Å; F174-L179 HydrophobicContact CD1-CD1 4.27Å; F174-L179 HydrophobicContact CE1-CD1 3.79Å; F174-L179 HydrophobicContact CE1-CG 4.23Å; F174-L179 HydrophobicContact CE2-CG 4.47Å; F174-L179 HydrophobicContact CZ-CD1 4.12Å; F174-L179 HydrophobicContact CZ-CD2 4.12Å; F174-L179 HydrophobicContact CZ-CG 4.1Å; F174-L179 PolarHBondContact O-N 2.87Å; F174-L179 VanDerWaalsContact O-N 3.11Å
175L97.3Very high96.1Very high0 Ų017.2 Ų17.20%012%0.119CC..Hα-helixtrans-59.6-48.8172.8-68.2170.2000111.3V149 V161 L171 T172 L179 G180 L181 V183 T374V149-L175 HydrophobicContact CB-CD2 3.81Å; V149-L175 HydrophobicContact CG1-CD1 4.44Å; V149-L175 HydrophobicContact CG1-CD2 3.65Å; V149-L175 HydrophobicContact CG2-CD2 4.49Å; V161-L175 HydrophobicContact CG1-CD1 4.05Å; L171-L175 HydrophobicContact CD1-CD1 4.14Å; L171-L175 HydrophobicContact CD1-CD2 4.39Å; L171-L175 HydrophobicContact CD1-CG 3.97Å; L171-L175 HydrophobicContact CD2-CD1 4.41Å; L171-L175 HydrophobicContact CG-CD1 3.8Å; L171-L175 HydrophobicContact CG-CG 4.13Å; L171-L175 WeakPolarHBondContact O-CG 3.42Å; L171-L175 PolarHBondContact O-N 2.68Å; T172-L175 PolarHBondContact O-N 3.04Å; L175-L179 HydrophobicContact CD2-CD1 4.32Å; L175-L179 CarbonylContact O-C 3.28Å; L175-L179 PolarHBondContact O-N 2.87Å; L175-G180 PolarHBondContact O-N 2.94Å; L175-L181 HydrophobicContact CB-CD1 4.36Å; L175-L181 HydrophobicContact CD2-CD1 3.97Å; L175-L181 PolarHBondContact O-N 3.34Å; L175-V183 HydrophobicContact CB-CG1 4.4Å; L175-V183 HydrophobicContact CB-CG2 3.64Å; L175-V183 HydrophobicContact CD1-CG1 4.17Å; L175-T374 HydrophobicContact CD1-CG2 4.34Å
176S96.4Very high96.2Very high0 Ų016.2 Ų16.20%011%0.108CC..Hα-helixtrans-65.8-74.1177.2-103.10000112.2T172 G178 G180 L181 G223 P224T172-S176 PolarHBondContact O-N 2.94Å; S176-G178 PolarHBondContact O-N 3.39Å; S176-G180 WeakPolarHBondContact O-CA 3.38Å; S176-G180 PolarHBondContact O-N 2.81Å; S176-L181 WeakPolarHBondContact CA-O 3.23Å; S176-L181 PolarHBondContact OG-O 2.8Å; S176-G223 WeakPolarHBondContact O-CA 3.49Å; S176-P224 VanDerWaalsContact CB-O 3.27Å; S176-P224 WeakPolarHBondContact CB-O 3.29Å; S176-P224 PolarHBondContact OG-O 2.87Å
177F94.3Very high96.2Very high20 Ų2017.2 Ų17.29%0.08811%0.112CC..Hα-helixtrans-79.4-21.3-168.3-58.6-63.3000113.7F130 R173 D200 L203 L204 P226F130-F177 HydrophobicContact CE1-CB 4.09Å; F130-F177 HydrophobicContact CZ-CB 4.15Å; R173-F177 HydrophobicContact CG-CD2 3.98Å; R173-F177 HydrophobicContact CG-CE2 4.41Å; R173-F177 PolarHBondContact O-N 3.27Å; F177-D200 HydrophobicContact CE2-CB 4.21Å; F177-L203 HydrophobicContact CB-CD2 4.23Å; F177-L203 HydrophobicContact CD2-CD2 3.5Å; F177-L203 VanDerWaalsContact CD2-CD2 3.5Å; F177-L203 HydrophobicContact CD2-CG 4.45Å; F177-L203 HydrophobicContact CE2-CD2 4.11Å; F177-L203 HydrophobicContact CG-CD2 4.15Å; F177-L204 HydrophobicContact CD1-CD2 4.46Å; F177-L204 HydrophobicContact CE1-CD2 3.65Å; F177-L204 HydrophobicContact CE1-CG 4.29Å; F177-L204 HydrophobicContact CZ-CD1 4.22Å; F177-L204 HydrophobicContact CZ-CD2 3.85Å; F177-L204 HydrophobicContact CZ-CG 3.96Å; F177-P226 VanDerWaalsContact CE2-CD 3.42Å; F177-P226 HydrophobicContact CE2-CG 4.09Å; F177-P226 VanDerWaalsContact CZ-CD 3.4Å; F177-P226 HydrophobicContact CZ-CG 4.49Å
178G93.3Very high96.2Very high33 Ų3318.5 Ų18.534%0.3412%0.121SC..Hα-helixtrans-95-29.9-177.900000114.5F174 S176F174-G178 CarbonylContact O-C 3.58Å; F174-G178 WeakPolarHBondContact O-CA 3.1Å; F174-G178 PolarHBondContact O-N 3.38Å; S176-G178 PolarHBondContact O-N 3.39Å
179L94.9Very high96Very high47 Ų4718.7 Ų18.725%0.24612%0.124CC..Hα-helixtrans-123.40.1-176.1-57176.7000114.1G146 K150 F174 L175 L181G146-L179 VanDerWaalsContact C-CD1 3.48Å; G146-L179 WeakPolarHBondContact O-CD1 3.39Å; K150-L179 HydrophobicContact CB-CD1 4.06Å; F174-L179 HydrophobicContact CD1-CD1 4.27Å; F174-L179 HydrophobicContact CE1-CD1 3.79Å; F174-L179 HydrophobicContact CE1-CG 4.23Å; F174-L179 HydrophobicContact CE2-CG 4.47Å; F174-L179 HydrophobicContact CZ-CD1 4.12Å; F174-L179 HydrophobicContact CZ-CD2 4.12Å; F174-L179 HydrophobicContact CZ-CG 4.1Å; F174-L179 PolarHBondContact O-N 2.87Å; F174-L179 VanDerWaalsContact O-N 3.11Å; L175-L179 HydrophobicContact CD2-CD1 4.32Å; L175-L179 CarbonylContact O-C 3.28Å; L175-L179 PolarHBondContact O-N 2.87Å; L179-L181 HydrophobicContact CB-CD1 4.5Å
180G94.2Very high95.9Very high40 Ų4022.6 Ų22.641%0.41215%0.149SC..  trans83.39169.400000115.8L175 S176L175-G180 PolarHBondContact O-N 2.94Å; S176-G180 WeakPolarHBondContact O-CA 3.38Å; S176-G180 PolarHBondContact O-N 2.81Å
181L95.6Very high95.9Very high0 Ų026.2 Ų26.20%017%0.173CC..  trans-82159.3-173.2-63.7168.3000112.4K150 C153 N159 V161 L175 S176 L179 V183 P224K150-L181 HydrophobicContact CB-CD1 4.4Å; K150-L181 HydrophobicContact CD-CD1 4.16Å; K150-L181 HydrophobicContact CD-CD2 3.85Å; K150-L181 HydrophobicContact CD-CG 4.16Å; C153-L181 HydrophobicContact CB-CD2 3.96Å; N159-L181 HydrophobicContact CB-CD2 4.21Å; V161-L181 HydrophobicContact CG2-CB 4.44Å; V161-L181 HydrophobicContact CG2-CD1 4Å; L175-L181 HydrophobicContact CB-CD1 4.36Å; L175-L181 HydrophobicContact CD2-CD1 3.97Å; L175-L181 PolarHBondContact O-N 3.34Å; S176-L181 WeakPolarHBondContact CA-O 3.23Å; S176-L181 PolarHBondContact OG-O 2.8Å; L179-L181 HydrophobicContact CB-CD1 4.5Å; L181-V183 HydrophobicContact CB-CG2 3.9Å; L181-P224 WeakPolarHBondContact O-CD 3.39Å; L181-P224 WeakPolarHBondContact O-CG 3.38Å
182S95.6Very high95.8Very high63 Ų6328.4 Ų28.444%0.44118%0.184SC..EExtended strand (participates in β ladder)trans-87.8123.9165.4-167.50000108.6N159 S160 V161N159-S182 PolarHBondContact O-N 3.36Å; S160-S182 CarbonylContact C-O 3.01Å; S160-S182 WeakPolarHBondContact CA-O 3.14Å; V161-S182 PolarHBondContact N-O 3.15Å
183V97.1Very high95.8Very high3 Ų329.2 Ų29.22%0.01819%0.189CC..EExtended strand (participates in β ladder)trans-136.9128.9-168.3-161.20000112.5V161 D163 T172 L175 L181 P226 C227V161-V183 HydrophobicContact CB-CG1 4.18Å; V161-V183 HydrophobicContact CB-CG2 4.46Å; V161-V183 HydrophobicContact CG1-CG1 4.44Å; V161-V183 VanDerWaalsContact O-CA 3.31Å; V161-V183 WeakPolarHBondContact O-CA 3.5Å; D163-V183 HydrophobicContact CB-CG1 4.4Å; T172-V183 HydrophobicContact CG2-CB 4.13Å; T172-V183 HydrophobicContact CG2-CG1 3.46Å; T172-V183 VanDerWaalsContact CG2-CG1 3.46Å; L175-V183 HydrophobicContact CB-CG1 4.4Å; L175-V183 HydrophobicContact CB-CG2 3.64Å; L175-V183 HydrophobicContact CD1-CG1 4.17Å; L181-V183 HydrophobicContact CB-CG2 3.9Å; V183-P226 WeakPolarHBondContact O-CA 3.27Å; V183-C227 PolarHBondContact O-N 2.78Å
184T97.4Very high95.8Very high18 Ų1832.4 Ų32.411%0.1121%0.213CC..EExtended strand (participates in β ladder)trans-111.4114.7168.7-61.10000109.7V161 V162 D163 I186 C227 V229 V246V161-T184 PolarHBondContact O-N 2.99Å; V162-T184 CarbonylContact C-O 3.48Å; V162-T184 WeakPolarHBondContact CA-O 3.41Å; D163-T184 PolarHBondContact N-O 3.4Å; T184-I186 HydrophobicContact CG2-CG1 4.45Å; T184-C227 CarbonylContact C-O 3.57Å; T184-C227 WeakPolarHBondContact CA-O 3.46Å; T184-C227 HydrophobicContact CG2-CB 4.28Å; T184-V229 HydrophobicContact CG2-CG2 3.85Å; T184-V246 HydrophobicContact CG2-CG1 4.38Å
185G97.6Very high95.7Very high0 Ų034.3 Ų34.30%022%0.223CC..EExtended strand (participates in β ladder)trans-80.8135.1167.700000111D163 C227 H228 V229D163-G185 CarbonylContact O-C 3.36Å; D163-G185 VanDerWaalsContact O-CA 3.29Å; D163-G185 WeakPolarHBondContact O-CA 3.29Å; G185-C227 PolarHBondContact N-O 3.14Å; G185-H228 CarbonylContact O-C 3.56Å; G185-H228 WeakPolarHBondContact O-CA 3.45Å; G185-V229 PolarHBondContact O-N 3.36Å
186I97Very high95.7Very high1 Ų134.3 Ų34.31%0.00522%0.223CC..EExtended strand (participates in β ladder)trans-116.7127.9169.4-57.1176.7000108.7V162 D163 V164 G165 S166 T184 V229 G231 V233 F242 V246V162-I186 HydrophobicContact CG1-CD1 3.85Å; V162-I186 HydrophobicContact CG1-CG1 4.28Å; D163-I186 PolarHBondContact O-N 2.67Å; V164-I186 HydrophobicContact CG1-CB 4.34Å; V164-I186 HydrophobicContact CG2-CB 4.45Å; V164-I186 HydrophobicContact CG2-CD1 4.43Å; G165-I186 PolarHBondContact N-O 2.83Å; S166-I186 PolarHBondContact N-O 3.2Å; T184-I186 HydrophobicContact CG2-CG1 4.45Å; I186-V229 HydrophobicContact CG1-CB 4.36Å; I186-G231 WeakPolarHBondContact CG2-O 3.43Å; I186-V233 HydrophobicContact CB-CG2 4.5Å; I186-V233 HydrophobicContact CD1-CG2 4.33Å; I186-V233 HydrophobicContact CG2-CG2 3.74Å; I186-F242 HydrophobicContact CD1-CE2 4.13Å; I186-V246 HydrophobicContact CD1-CG2 3.88Å
187E95.7Very high95.7Very high28 Ų2837.3 Ų37.313%0.13124%0.244CC..EExtended strand (participates in β ladder)trans-141.5140.4178.9175.353.4-110.900110.3G167 D189 L192 V193 V229 A230 G231G167-E187 WeakPolarHBondContact CA-OE2 3.47Å; G167-E187 PolarHBondContact N-OE2 3.3Å; E187-D189 PolarHBondContact OE1-N 2.94Å; E187-L192 HydrophobicContact CG-CB 3.79Å; E187-L192 HydrophobicContact CG-CD1 4.19Å; E187-V193 HydrophobicContact CB-CG2 3.78Å; E187-V193 HydrophobicContact CG-CG2 4.28Å; E187-V229 PolarHBondContact N-O 2.7Å; E187-V229 VanDerWaalsContact N-O 3.1Å; E187-A230 CarbonylContact O-C 3.6Å; E187-A230 WeakPolarHBondContact O-CA 3.18Å; E187-G231 CarbonylContact C-O 3.58Å; E187-G231 PolarHBondContact O-N 3.01Å
188A93.5Very high95.7Very high37 Ų3742.4 Ų42.431%0.30627%0.266SS..SBendtrans-81-25.1-174.500000113.1P190 W232 I421A188-P190 WeakPolarHBondContact O-CD 3.36Å; A188-W232 HydrophobicContact CB-CB 4.36Å; A188-I421 HydrophobicContact CB-CD1 4.34Å
189D93.2Very high95.8Very high62 Ų6242.3 Ų42.333%0.33226%0.255SS..  trans-90.7112173.9-178.5-0.3000111.7E187 T191 L192 V193E187-D189 PolarHBondContact OE1-N 2.94Å; D189-T191 PolarHBondContact O-N 3Å; D189-T191 VanDerWaalsContact O-N 3.12Å; D189-T191 WeakPolarHBondContact OD1-CA 3.34Å; D189-T191 WeakPolarHBondContact OD1-CB 3.46Å; D189-T191 PolarHBondContact OD1-N 3.34Å; D189-T191 PolarHBondContact OD1-OG1 3.02Å; D189-L192 HydrophobicContact CB-CB 4.28Å; D189-L192 HydrophobicContact CB-CD1 4.01Å; D189-L192 HydrophobicContact CB-CG 3.96Å; D189-L192 PolarHBondContact O-N 2.95Å; D189-V193 PolarHBondContact O-N 3.45Å
190P94.6Very high95.8Very high82 Ų8240.6 Ų40.653%0.53225%0.246SC..Hα-helixtrans-59.5-23.7176.6-21.633.5000113.7A188 V193 S194 A230A188-P190 WeakPolarHBondContact O-CD 3.36Å; P190-V193 PolarHBondContact O-N 2.8Å; P190-S194 WeakPolarHBondContact O-CB 3.47Å; P190-S194 PolarHBondContact O-N 2.97Å; P190-A230 HydrophobicContact CB-CB 4.26Å; P190-A230 HydrophobicContact CG-CB 4.27Å
191T96.6Very high95.8Very high91 Ų9140.6 Ų40.656%0.55825%0.247SC*.Hα-helixtrans-66.4-41.2176-37.80000110.9D189 M195D189-T191 PolarHBondContact O-N 3Å; D189-T191 VanDerWaalsContact O-N 3.12Å; D189-T191 WeakPolarHBondContact OD1-CA 3.34Å; D189-T191 WeakPolarHBondContact OD1-CB 3.46Å; D189-T191 PolarHBondContact OD1-N 3.34Å; D189-T191 PolarHBondContact OD1-OG1 3.02Å; T191-M195 WeakPolarHBondContact O-CB 3.15Å; T191-M195 VanDerWaalsContact O-CG 3.26Å; T191-M195 WeakPolarHBondContact O-CG 3.48Å; T191-M195 PolarHBondContact O-N 3.08Å
192L96.2Very high95.6Very high50 Ų5043.3 Ų43.326%0.26226%0.26SS..Hα-helixtrans-70.9-38.7177.5-64.2-178.7000111.3G167 Q168 E187 D189 M195 A196G167-L192 CarbonylContact O-C 3.52Å; Q168-L192 HydrophobicContact CG-CD2 3.97Å; E187-L192 HydrophobicContact CG-CB 3.79Å; E187-L192 HydrophobicContact CG-CD1 4.19Å; D189-L192 HydrophobicContact CB-CB 4.28Å; D189-L192 HydrophobicContact CB-CD1 4.01Å; D189-L192 HydrophobicContact CB-CG 3.96Å; D189-L192 PolarHBondContact O-N 2.95Å; L192-M195 CarbonylContact O-C 3.5Å; L192-M195 PolarHBondContact O-N 3.03Å; L192-A196 PolarHBondContact O-N 2.52Å
193V96.4Very high95.4Very high16 Ų1640.8 Ų40.810%0.09724%0.241CC..Hα-helixtrans-58.8-49.9171.3171.50000111.6E187 D189 P190 M195 A196 S197 H228 A230E187-V193 HydrophobicContact CB-CG2 3.78Å; E187-V193 HydrophobicContact CG-CG2 4.28Å; D189-V193 PolarHBondContact O-N 3.45Å; P190-V193 PolarHBondContact O-N 2.8Å; V193-M195 VanDerWaalsContact C-N 3.29Å; V193-M195 PolarHBondContact O-N 3.04Å; V193-A196 WeakPolarHBondContact O-CB 3.39Å; V193-A196 PolarHBondContact O-N 3.22Å; V193-A196 VanDerWaalsContact O-N 3.07Å; V193-S197 PolarHBondContact O-N 3.44Å; V193-S197 VanDerWaalsContact O-N 3.11Å; V193-S197 PolarHBondContact O-OG 3.1Å; V193-H228 HydrophobicContact CG1-CB 3.87Å; V193-A230 HydrophobicContact CG1-CB 4.47Å; V193-A230 HydrophobicContact CG2-CB 4.12Å
194S96.8Very high95.1Very high79 Ų7944 Ų4455%0.55226%0.258SS*.Hα-helixtrans-58.7-41.4176.3-178.60000111.9P190 K198P190-S194 WeakPolarHBondContact O-CB 3.47Å; P190-S194 PolarHBondContact O-N 2.97Å; S194-K198 VanDerWaalsContact O-CB 3.22Å; S194-K198 WeakPolarHBondContact O-CB 3.48Å; S194-K198 PolarHBondContact O-N 3.43Å
195M96.3Very high94.7Very high51 Ų5152.2 Ų52.225%0.25129%0.287SS..Hα-helixtrans-67.6-32.5174.8-73.2-68.8-72.200113.2Q168 T191 L192 V193 K198 Y199Q168-M195 HydrophobicContact CG-CB 4.46Å; T191-M195 WeakPolarHBondContact O-CB 3.15Å; T191-M195 VanDerWaalsContact O-CG 3.26Å; T191-M195 WeakPolarHBondContact O-CG 3.48Å; T191-M195 PolarHBondContact O-N 3.08Å; L192-M195 CarbonylContact O-C 3.5Å; L192-M195 PolarHBondContact O-N 3.03Å; V193-M195 VanDerWaalsContact C-N 3.29Å; V193-M195 PolarHBondContact O-N 3.04Å; M195-K198 HydrophobicContact SD-CD 4.01Å; M195-Y199 HydrophobicContact CE-CE1 4.37Å; M195-Y199 HydrophobicContact CE-CE2 4.07Å; M195-Y199 VanDerWaalsContact CE-OH 3.29Å; M195-Y199 WeakPolarHBondContact CE-OH 3.28Å; M195-Y199 WeakPolarHBondContact O-CD2 3.32Å; M195-Y199 VanDerWaalsContact O-CG 3.31Å; M195-Y199 PolarHBondContact O-N 2.85Å
196A96.4Very high94.2Very high0 Ų054.8 Ų54.80%030%0.302CS..Hα-helixtrans-63.3-56.6174.500000111.1R173 L192 V193 K198 Y199 D200R173-A196 PolarHBondContact NH2-O 2.84Å; L192-A196 PolarHBondContact O-N 2.52Å; V193-A196 WeakPolarHBondContact O-CB 3.39Å; V193-A196 PolarHBondContact O-N 3.22Å; V193-A196 VanDerWaalsContact O-N 3.07Å; A196-K198 VanDerWaalsContact C-N 3.26Å; A196-K198 PolarHBondContact O-N 3.1Å; A196-Y199 WeakPolarHBondContact O-CA 3.43Å; A196-Y199 PolarHBondContact O-N 3.09Å; A196-D200 PolarHBondContact O-N 2.9Å
197S96.2Very high93.7Very high62 Ų6257.2 Ų57.243%0.43432%0.315SS..Hα-helixtrans-58.3-37.8177.5-540000112.3V193 Y199 D200 G201V193-S197 PolarHBondContact O-N 3.44Å; V193-S197 VanDerWaalsContact O-N 3.11Å; V193-S197 PolarHBondContact O-OG 3.1Å; S197-Y199 VanDerWaalsContact C-N 3.32Å; S197-Y199 PolarHBondContact O-N 2.94Å; S197-D200 PolarHBondContact O-N 2.84Å; S197-G201 PolarHBondContact O-N 3.24Å
198K95.7Very high93.2Very high128 Ų12859.3 Ų59.356%0.55733%0.325SS*.Hα-helixtrans-64-31.4173.9-179.9176.9178.2177.60113.3S194 M195 A196 Q202S194-K198 VanDerWaalsContact O-CB 3.22Å; S194-K198 WeakPolarHBondContact O-CB 3.48Å; S194-K198 PolarHBondContact O-N 3.43Å; M195-K198 HydrophobicContact SD-CD 4.01Å; A196-K198 VanDerWaalsContact C-N 3.26Å; A196-K198 PolarHBondContact O-N 3.1Å; K198-Q202 WeakPolarHBondContact O-CG 3.39Å; K198-Q202 PolarHBondContact O-NE2 3.18Å
199Y95.2Very high92.8Very high30 Ų3062.5 Ų62.512%0.11833%0.332CS..Hα-helixtrans-79.8-30.7173.8-70.2-40.3000112.4H133 Q168 H170 M195 A196 S197 Q202 L203H133-Y199 HydrophobicContact CB-CE1 4.41Å; H133-Y199 AromaticContact CD2-CD1 3.64Å; H133-Y199 AromaticContact CD2-CE1 3.16Å; H133-Y199 WeakPolarHBondContact CD2-CE1 3.36Å; H133-Y199 AromaticContact CD2-CZ 3.71Å; H133-Y199 AromaticContact CG-CE1 3.71Å; H133-Y199 AromaticContact CG-CZ 3.77Å; H133-Y199 AromaticContact NE2-CE1 3.45Å; H133-Y199 WeakPolarHBondContact NE2-CE1 3.4Å; Q168-Y199 HydrophobicContact CB-CD2 4.28Å; Q168-Y199 HydrophobicContact CB-CE2 4.15Å; Q168-Y199 HydrophobicContact CG-CE2 4.38Å; H170-Y199 AromaticContact CE1-CD2 3.42Å; H170-Y199 VanDerWaalsContact CE1-CD2 3.42Å; H170-Y199 WeakPolarHBondContact CE1-CD2 3.45Å; H170-Y199 AromaticContact CE1-CE2 3.5Å; H170-Y199 VanDerWaalsContact CE1-CE2 3.5Å; H170-Y199 WeakPolarHBondContact CE1-CE2 3.21Å; H170-Y199 AromaticContact NE2-CE2 3.85Å; M195-Y199 HydrophobicContact CE-CE1 4.37Å; M195-Y199 HydrophobicContact CE-CE2 4.07Å; M195-Y199 VanDerWaalsContact CE-OH 3.29Å; M195-Y199 WeakPolarHBondContact CE-OH 3.28Å; M195-Y199 WeakPolarHBondContact O-CD2 3.32Å; M195-Y199 VanDerWaalsContact O-CG 3.31Å; M195-Y199 PolarHBondContact O-N 2.85Å; A196-Y199 WeakPolarHBondContact O-CA 3.43Å; A196-Y199 PolarHBondContact O-N 3.09Å; S197-Y199 VanDerWaalsContact C-N 3.32Å; S197-Y199 PolarHBondContact O-N 2.94Å; Y199-Q202 PolarHBondContact O-N 3.45Å; Y199-L203 PolarHBondContact O-N 3.45Å
200D94.9Very high92.3Very high11 Ų1162 Ų626%0.05933%0.328CS..Hα-helixtrans-66.4-45.4174.3-59.9-36000111.9R173 F177 A196 S197 Q202 L203 L204 H228R173-D200 WeakPolarHBondContact CG-OD1 3.37Å; R173-D200 IonicContact CZ-OD1 3.27Å; R173-D200 IonicContact NE-OD1 2.85Å; R173-D200 PolarHBondContact NE-OD1 3.09Å; R173-D200 IonicContact NH2-OD1 3.82Å; R173-D200 PolarHBondContact NH2-OD1 2.68Å; R173-D200 IonicContact NH2-OD2 4Å; F177-D200 HydrophobicContact CE2-CB 4.21Å; A196-D200 PolarHBondContact O-N 2.9Å; S197-D200 PolarHBondContact O-N 2.84Å; D200-Q202 VanDerWaalsContact C-N 3.26Å; D200-Q202 PolarHBondContact O-N 2.98Å; D200-L203 WeakPolarHBondContact O-CB 3.27Å; D200-L203 PolarHBondContact O-N 3.49Å; D200-L204 WeakPolarHBondContact O-CG 3.29Å; D200-L204 PolarHBondContact O-N 3.37Å; D200-H228 IonicContact OD2-CD2 3.27Å; D200-H228 PolarHBondContact OD2-CD2 3.21Å; D200-H228 IonicContact OD2-CE1 2.77Å; D200-H228 IonicContact OD2-NE2 3.92Å; D200-H228 PolarHBondContact OD2-NE2 3Å
201G93.1Very high91.6Very high41 Ų4166.2 Ų66.242%0.42333%0.333SS..Hα-helixtrans-58.4-36.8174.200000113.2S197 W205S197-G201 PolarHBondContact O-N 3.24Å; G201-W205 WeakPolarHBondContact O-CB 3.44Å; G201-W205 PolarHBondContact O-N 3.33Å
202Q92.9Very high90.7Very high57 Ų5768.1 Ų68.127%0.26634%0.336SS..Hα-helixtrans-69-34.5173.8-73.9171.966.800113.2K198 Y199 D200 T206K198-Q202 WeakPolarHBondContact O-CG 3.39Å; K198-Q202 PolarHBondContact O-NE2 3.18Å; Y199-Q202 PolarHBondContact O-N 3.45Å; D200-Q202 VanDerWaalsContact C-N 3.26Å; D200-Q202 PolarHBondContact O-N 2.98Å; Q202-T206 WeakPolarHBondContact O-CB 3.42Å; Q202-T206 PolarHBondContact O-N 2.71Å; Q202-T206 PolarHBondContact O-OG1 3.34Å
203L91.3Very high89.7Confident9 Ų974.6 Ų74.65%0.04736%0.356CS..Hα-helixtrans-70.4-48.7176177.358.9000110.9I129 F130 R173 F177 Y199 D200 W205 T206 L207I129-L203 HydrophobicContact CB-CD1 3.61Å; I129-L203 HydrophobicContact CD1-CD1 3.97Å; I129-L203 HydrophobicContact CG1-CD1 3.89Å; I129-L203 HydrophobicContact CG2-CD1 4.49Å; F130-L203 HydrophobicContact CD1-CD2 4.21Å; F130-L203 HydrophobicContact CE1-CD2 3.78Å; R173-L203 HydrophobicContact CG-CD2 3.49Å; R173-L203 VanDerWaalsContact CG-CD2 3.49Å; F177-L203 HydrophobicContact CB-CD2 4.23Å; F177-L203 HydrophobicContact CD2-CD2 3.5Å; F177-L203 VanDerWaalsContact CD2-CD2 3.5Å; F177-L203 HydrophobicContact CD2-CG 4.45Å; F177-L203 HydrophobicContact CE2-CD2 4.11Å; F177-L203 HydrophobicContact CG-CD2 4.15Å; Y199-L203 PolarHBondContact O-N 3.45Å; D200-L203 WeakPolarHBondContact O-CB 3.27Å; D200-L203 PolarHBondContact O-N 3.49Å; L203-W205 VanDerWaalsContact C-N 3.34Å; L203-W205 PolarHBondContact O-N 2.94Å; L203-T206 CarbonylContact O-C 3.58Å; L203-T206 WeakPolarHBondContact O-CA 3.49Å; L203-T206 WeakPolarHBondContact O-CB 3.39Å; L203-T206 PolarHBondContact O-N 3.17Å; L203-L207 HydrophobicContact CD1-CD1 4.37Å; L203-L207 HydrophobicContact CD1-CG 4.28Å; L203-L207 HydrophobicContact CG-CD1 4.16Å; L203-L207 WeakPolarHBondContact O-CG 3.41Å; L203-L207 PolarHBondContact O-N 2.85Å
204L91.1Very high88.5Confident71 Ų7179.9 Ų79.937%0.37238%0.378SS..Hα-helixtrans-56.1-46.3175.7-73170.2000112F177 D200 T206 L207 E208F177-L204 HydrophobicContact CD1-CD2 4.46Å; F177-L204 HydrophobicContact CE1-CD2 3.65Å; F177-L204 HydrophobicContact CE1-CG 4.29Å; F177-L204 HydrophobicContact CZ-CD1 4.22Å; F177-L204 HydrophobicContact CZ-CD2 3.85Å; F177-L204 HydrophobicContact CZ-CG 3.96Å; D200-L204 WeakPolarHBondContact O-CG 3.29Å; D200-L204 PolarHBondContact O-N 3.37Å; L204-T206 PolarHBondContact O-N 3.07Å; L204-L207 PolarHBondContact O-N 3.01Å; L204-E208 PolarHBondContact O-N 3.27Å
205W87.9Confident86.5Confident190 Ų19083.7 Ų83.772%0.7239%0.392SS*.Hα-helixtrans-60.2-34.2174.8-179.4-101.5000113G201 L203 K209G201-W205 WeakPolarHBondContact O-CB 3.44Å; G201-W205 PolarHBondContact O-N 3.33Å; L203-W205 VanDerWaalsContact C-N 3.34Å; L203-W205 PolarHBondContact O-N 2.94Å; W205-K209 VanDerWaalsContact O-CB 3.26Å; W205-K209 WeakPolarHBondContact O-CB 3.48Å; W205-K209 PolarHBondContact O-N 3.39Å
206T87.9Confident84.4Confident54 Ų5483.8 Ų83.833%0.33141%0.406SS..Hα-helixtrans-73.8-42.7177.6-59.90000111.2I129 Q202 L203 L204 K209 E210I129-T206 HydrophobicContact CG2-CG2 4.18Å; Q202-T206 WeakPolarHBondContact O-CB 3.42Å; Q202-T206 PolarHBondContact O-N 2.71Å; Q202-T206 PolarHBondContact O-OG1 3.34Å; L203-T206 CarbonylContact O-C 3.58Å; L203-T206 WeakPolarHBondContact O-CA 3.49Å; L203-T206 WeakPolarHBondContact O-CB 3.39Å; L203-T206 PolarHBondContact O-N 3.17Å; L204-T206 PolarHBondContact O-N 3.07Å; T206-K209 PolarHBondContact O-N 2.88Å; T206-E210 PolarHBondContact O-N 3.3Å
207L85.7Confident82.1Confident52 Ų5289.3 Ų89.327%0.27244%0.442SS..Hα-helixtrans-61.6-48.7176.3-73.6172.5000111.9I129 L203 L204 K209 E210 R211I129-L207 HydrophobicContact CD1-CD2 3.68Å; L203-L207 HydrophobicContact CD1-CD1 4.37Å; L203-L207 HydrophobicContact CD1-CG 4.28Å; L203-L207 HydrophobicContact CG-CD1 4.16Å; L203-L207 WeakPolarHBondContact O-CG 3.41Å; L203-L207 PolarHBondContact O-N 2.85Å; L204-L207 PolarHBondContact O-N 3.01Å; L207-K209 VanDerWaalsContact C-N 3.33Å; L207-K209 PolarHBondContact O-N 3.28Å; L207-E210 PolarHBondContact O-N 3.05Å; L207-E210 VanDerWaalsContact O-N 3.16Å; L207-R211 WeakPolarHBondContact O-CB 3.28Å; L207-R211 PolarHBondContact O-N 2.97Å
208E85.9Confident79.8Confident73 Ų7391.9 Ų91.934%0.34146%0.457SS..Hα-helixtrans-65.1-37.5178.9-178.252.6-146.200111.2L204 E210 R211 Q212L204-E208 PolarHBondContact O-N 3.27Å; E208-E210 PolarHBondContact O-N 3.11Å; E208-R211 WeakPolarHBondContact O-CB 3.45Å; E208-R211 PolarHBondContact O-N 2.83Å; E208-R211 WeakPolarHBondContact OE2-CD 3.21Å; E208-R211 IonicContact OE2-CZ 2.72Å; E208-R211 IonicContact OE2-NE 2.85Å; E208-R211 IonicContact OE2-NH1 2.8Å; E208-R211 PolarHBondContact OE2-NH1 3.12Å; E208-Q212 VanDerWaalsContact O-CG 3.31Å; E208-Q212 WeakPolarHBondContact O-CG 3.47Å; E208-Q212 PolarHBondContact O-N 3.4Å; E208-Q212 WeakPolarHBondContact OE1-CG 3.47Å; E208-Q212 PolarHBondContact OE1-NE2 2.86Å
209K85.5Confident77.5Confident104 Ų10492.5 Ų92.545%0.45247%0.465SS..Hα-helixtrans-66.5-32.8172.7-173.1171.6-177.1173.20113.5W205 T206 L207 R213W205-K209 VanDerWaalsContact O-CB 3.26Å; W205-K209 WeakPolarHBondContact O-CB 3.48Å; W205-K209 PolarHBondContact O-N 3.39Å; T206-K209 PolarHBondContact O-N 2.88Å; L207-K209 VanDerWaalsContact C-N 3.33Å; L207-K209 PolarHBondContact O-N 3.28Å; K209-R213 VanDerWaalsContact O-CD 3.3Å; K209-R213 WeakPolarHBondContact O-CD 3.29Å; K209-R213 VanDerWaalsContact O-CG 3.23Å; K209-R213 WeakPolarHBondContact O-CG 3.44Å; K209-R213 PolarHBondContact O-N 3.15Å
210E82.5Confident75.2Confident50 Ų5096.2 Ų96.223%0.23450%0.496CS..Hα-helixtrans-72.7-36.3171.7-79.1-158.1-154.200112.4H128 T206 L207 E208 R213 K214H128-E210 IonicContact CE1-OE1 2.74Å; H128-E210 PolarHBondContact CE1-OE1 2.88Å; H128-E210 IonicContact NE2-OE1 3.77Å; H128-E210 PolarHBondContact NE2-OE1 3.09Å; T206-E210 PolarHBondContact O-N 3.3Å; L207-E210 PolarHBondContact O-N 3.05Å; L207-E210 VanDerWaalsContact O-N 3.16Å; E208-E210 PolarHBondContact O-N 3.11Å; E210-R213 PolarHBondContact O-N 3.17Å; E210-K214 WeakPolarHBondContact O-CG 3.39Å; E210-K214 PolarHBondContact O-N 2.85Å; E210-K214 IonicContact OE2-NZ 3.66Å; E210-K214 PolarHBondContact OE2-NZ 3.39Å
211R78.4Confident73.1Confident172 Ų172107 Ų10765%0.64954%0.536SS*.Hα-helixtrans-61-52.3175.1-173.8-167-173.4-174.12111.5L207 E208 R213 K214L207-R211 WeakPolarHBondContact O-CB 3.28Å; L207-R211 PolarHBondContact O-N 2.97Å; E208-R211 WeakPolarHBondContact O-CB 3.45Å; E208-R211 PolarHBondContact O-N 2.83Å; E208-R211 WeakPolarHBondContact OE2-CD 3.21Å; E208-R211 IonicContact OE2-CZ 2.72Å; E208-R211 IonicContact OE2-NE 2.85Å; E208-R211 IonicContact OE2-NH1 2.8Å; E208-R211 PolarHBondContact OE2-NH1 3.12Å; R211-R213 PolarHBondContact O-N 3.13Å; R211-R213 VanDerWaalsContact O-N 3.1Å; R211-K214 PolarHBondContact O-N 3.36Å; R211-K214 VanDerWaalsContact O-N 3.09Å
212Q78.7Confident71.6Confident131 Ų131108.9 Ų108.961%0.61254%0.542SS*.Hα-helixtrans-60-19.6177.2-70173.311.200113.8E208E208-Q212 VanDerWaalsContact O-CG 3.31Å; E208-Q212 WeakPolarHBondContact O-CG 3.47Å; E208-Q212 PolarHBondContact O-N 3.4Å; E208-Q212 WeakPolarHBondContact OE1-CG 3.47Å; E208-Q212 PolarHBondContact OE1-NE2 2.86Å
213R75.5Confident70.4Confident185 Ų185106.6 Ų106.670%0.69853%0.534SS*.Hα-helixtrans-90.3-17.4178.1-78.9172.3161.2-166.8-12114.5K209 E210 R211K209-R213 VanDerWaalsContact O-CD 3.3Å; K209-R213 WeakPolarHBondContact O-CD 3.29Å; K209-R213 VanDerWaalsContact O-CG 3.23Å; K209-R213 WeakPolarHBondContact O-CG 3.44Å; K209-R213 PolarHBondContact O-N 3.15Å; E210-R213 PolarHBondContact O-N 3.17Å; R211-R213 PolarHBondContact O-N 3.13Å; R211-R213 VanDerWaalsContact O-N 3.1Å
214K69.9Low70.1Confident128 Ų128109.3 Ų109.356%0.55755%0.552SS**Hα-helixtrans-102.3-16.2-168.1-80171.5174.3162.90114.7E210 R211 G216E210-K214 WeakPolarHBondContact O-CG 3.39Å; E210-K214 PolarHBondContact O-N 2.85Å; E210-K214 IonicContact OE2-NZ 3.66Å; E210-K214 PolarHBondContact OE2-NZ 3.39Å; R211-K214 PolarHBondContact O-N 3.36Å; R211-K214 VanDerWaalsContact O-N 3.09Å; K214-G216 PolarHBondContact O-N 3.04Å
215N54.8Low70.1Confident159 Ų159109.7 Ų109.785%0.8556%0.561SS**  trans45.128.2178.5-78.94.2000115.3
216G52.4Low70.4Confident52 Ų52101.3 Ų101.354%0.53653%0.531SS..  trans-105.7168.5-176.700000112.8K214K214-G216 PolarHBondContact O-N 3.04Å
217P48.5Very low70.8Confident117 Ų117100.1 Ų100.176%0.7653%0.525SS*.SBendtrans-57.7155.3169.227.4-35.1000110.7I219P217-I219 PolarHBondContact O-N 3.38Å; P217-I219 VanDerWaalsContact O-N 3.1Å
218P48.6Very low71.3Confident116 Ų11698.9 Ų98.975%0.75352%0.517SS*.PPolyproline II helixtrans-60.5117.9-176.224.7-34.1000110.9S220P218-S220 PolarHBondContact O-N 3.39Å
219I46.2Very low71.7Confident140 Ų14096.3 Ų96.372%0.71851%0.506SS*.PPolyproline II helixtrans-56.8135.3165.1-62.6175.1000107.3P217 R221P217-I219 PolarHBondContact O-N 3.38Å; P217-I219 VanDerWaalsContact O-N 3.1Å; I219-R221 PolarHBondContact O-N 3.15Å; I219-R221 VanDerWaalsContact O-N 3.16Å
220S47.8Very low72.1Confident109 Ų10994 Ų9476%0.76251%0.507SS*.SBendtrans-46.4116.5-170.950.60000113P218P218-S220 PolarHBondContact O-N 3.39Å
221R51.3Low72.6Confident237 Ų23792.4 Ų92.489%0.89450%0.504SS*.  trans14.7101.1170.3-79.9178.6159.5175.7-7.3115.1I219 G223I219-R221 PolarHBondContact O-N 3.15Å; I219-R221 VanDerWaalsContact O-N 3.16Å; R221-G223 PolarHBondContact O-N 3.07Å
222S61.7Low73.2Confident81 Ų8187.8 Ų87.857%0.56649%0.486SS*.PPolyproline II helixtrans-53.1131.1149.852.30000108.6
223G67.3Low73.8Confident9 Ų982 Ų829%0.09346%0.46CS..PPolyproline II helixtrans-61168.417600000112.8S176 R221S176-G223 WeakPolarHBondContact O-CA 3.49Å; R221-G223 PolarHBondContact O-N 3.07Å
224P85.4Confident74.4Confident65 Ų6576 Ų7642%0.42244%0.442SS..PPolyproline II helixtrans-57.8148.3175.128.5-36.6000110.6S176 L181S176-P224 VanDerWaalsContact CB-O 3.27Å; S176-P224 WeakPolarHBondContact CB-O 3.29Å; S176-P224 PolarHBondContact OG-O 2.87Å; L181-P224 WeakPolarHBondContact O-CD 3.39Å; L181-P224 WeakPolarHBondContact O-CG 3.38Å
225S90.3Very high75.1Confident79 Ų7971.5 Ų71.555%0.55243%0.425SS*.PPolyproline II helixtrans-54.6134.2171.7-630000110.2
226P94.8Very high76.6Confident14 Ų1470.2 Ų70.29%0.09141%0.412CS..PPolyproline II helixtrans-67.3144.9176.729.5-34.3000110.1T172 F177 V183T172-P226 HydrophobicContact CG2-CB 3.98Å; F177-P226 VanDerWaalsContact CE2-CD 3.42Å; F177-P226 HydrophobicContact CE2-CG 4.09Å; F177-P226 VanDerWaalsContact CZ-CD 3.4Å; F177-P226 HydrophobicContact CZ-CG 4.49Å; V183-P226 WeakPolarHBondContact O-CA 3.27Å
227C95.1Very high78.3Confident30 Ų3069 Ų6920%0.20340%0.397CS..EExtended strand (participates in β ladder)trans-87.1146.2166.3-179.90000109.3V183 T184 G185 G249V183-C227 PolarHBondContact O-N 2.78Å; T184-C227 CarbonylContact C-O 3.57Å; T184-C227 WeakPolarHBondContact CA-O 3.46Å; T184-C227 HydrophobicContact CG2-CB 4.28Å; G185-C227 PolarHBondContact N-O 3.14Å; C227-G249 WeakPolarHBondContact SG-CA 3.44Å; C227-G249 PolarHBondContact SG-O 2.9Å
228H96.4Very high80.4Confident25 Ų2565.9 Ų65.912%0.11638%0.378CS..EExtended strand (participates in β ladder)trans-128.9125.6169.6-55.6-77.2000110.3G185 V193 D200G185-H228 CarbonylContact O-C 3.56Å; G185-H228 WeakPolarHBondContact O-CA 3.45Å; V193-H228 HydrophobicContact CG1-CB 3.87Å; D200-H228 IonicContact OD2-CD2 3.27Å; D200-H228 PolarHBondContact OD2-CD2 3.21Å; D200-H228 IonicContact OD2-CE1 2.77Å; D200-H228 IonicContact OD2-NE2 3.92Å; D200-H228 PolarHBondContact OD2-NE2 3Å
229V95.3Very high82.5Confident19 Ų1964.3 Ų64.312%0.11536%0.357CS..EExtended strand (participates in β ladder)trans-111123.7-178.8178.10000109.2T184 G185 I186 E187 G231 Q245T184-V229 HydrophobicContact CG2-CG2 3.85Å; G185-V229 PolarHBondContact O-N 3.36Å; I186-V229 HydrophobicContact CG1-CB 4.36Å; E187-V229 PolarHBondContact N-O 2.7Å; E187-V229 VanDerWaalsContact N-O 3.1Å; V229-G231 PolarHBondContact O-N 3.21Å; V229-Q245 HydrophobicContact CG1-CG 4.46Å
230A94.5Very high84.8Confident56 Ų5664 Ų6446%0.46335%0.35SS..EExtended strand (participates in β ladder)trans-76.6115167.700000109.4E187 P190 V193E187-A230 CarbonylContact O-C 3.6Å; E187-A230 WeakPolarHBondContact O-CA 3.18Å; P190-A230 HydrophobicContact CB-CB 4.26Å; P190-A230 HydrophobicContact CG-CB 4.27Å; V193-A230 HydrophobicContact CG1-CB 4.47Å; V193-A230 HydrophobicContact CG2-CB 4.12Å
231G91.6Very high86.8Confident16 Ų1663 Ų6317%0.16534%0.337CS..  trans179.9139.1-178.300000113.9I186 E187 V229I186-G231 WeakPolarHBondContact CG2-O 3.43Å; E187-G231 CarbonylContact C-O 3.58Å; E187-G231 PolarHBondContact O-N 3.01Å; V229-G231 PolarHBondContact O-N 3.21Å
232W90.9Very high88.8Confident75 Ų7551.8 Ų51.828%0.28429%0.294SS..  trans-79.7132.6165.7178.976.6000109.6A188 N234 Q245 P423A188-W232 HydrophobicContact CB-CB 4.36Å; W232-N234 HydrophobicContact CE3-CB 3.88Å; W232-N234 HydrophobicContact CH2-CB 4.13Å; W232-N234 VanDerWaalsContact CZ3-CA 3.48Å; W232-N234 HydrophobicContact CZ3-CB 3.44Å; W232-N234 VanDerWaalsContact CZ3-CB 3.44Å; W232-N234 PolarHBondContact O-N 2.99Å; W232-Q245 PolarHBondContact O-NE2 3.28Å; W232-P423 HydrophobicContact CE3-CB 4.49Å; W232-P423 HydrophobicContact CH2-CB 3.87Å; W232-P423 HydrophobicContact CZ3-CB 3.84Å
233V91.4Very high90.2Very high10 Ų1049.1 Ų49.16%0.06128%0.275CS..  trans-87.5108.8176.2-179.20000109V164 I186 F242 T385V164-V233 HydrophobicContact CG1-CB 4.37Å; V164-V233 HydrophobicContact CG1-CG2 3.62Å; I186-V233 HydrophobicContact CB-CG2 4.5Å; I186-V233 HydrophobicContact CD1-CG2 4.33Å; I186-V233 HydrophobicContact CG2-CG2 3.74Å; V233-F242 HydrophobicContact CG1-CD2 3.82Å; V233-F242 HydrophobicContact CG1-CE2 3.81Å; V233-F242 HydrophobicContact CG2-CE2 4.2Å; V233-T385 HydrophobicContact CB-CG2 4.25Å; V233-T385 HydrophobicContact CG1-CG2 3.69Å
234N88.4Confident91.3Very high59 Ų5954.6 Ų54.632%0.31630%0.296SS..  trans-73.6123.6-179.1179.13.5000111W232 K236 A237 H389W232-N234 HydrophobicContact CE3-CB 3.88Å; W232-N234 HydrophobicContact CH2-CB 4.13Å; W232-N234 VanDerWaalsContact CZ3-CA 3.48Å; W232-N234 HydrophobicContact CZ3-CB 3.44Å; W232-N234 VanDerWaalsContact CZ3-CB 3.44Å; W232-N234 PolarHBondContact O-N 2.99Å; N234-K236 PolarHBondContact O-N 3.29Å; N234-K236 PolarHBondContact OD1-N 2.96Å; N234-A237 HydrophobicContact CB-CB 3.82Å; N234-A237 PolarHBondContact O-N 2.77Å; N234-H389 PolarHBondContact O-NE2 2.79Å
235P84.7Confident91.5Very high33 Ų3353.7 Ų53.721%0.21429%0.286CS..THydrogen-bonded Turntrans-65.2-21.7175.125.2-33000114.1T385P235-T385 HydrophobicContact CB-CG2 4.28Å
236K85.7Confident91.4Very high133 Ų13351 Ų5158%0.57827%0.266SS*.THydrogen-bonded Turntrans-98.83.4178.2-61.6-168176.1-1690113.9N234N234-K236 PolarHBondContact O-N 3.29Å; N234-K236 PolarHBondContact OD1-N 2.96Å
237A88.8Confident90.6Very high25 Ų2552 Ų5221%0.20728%0.279CS..SBendtrans-68.7149.917400000111N234 D241N234-A237 HydrophobicContact CB-CB 3.82Å; N234-A237 PolarHBondContact O-N 2.77Å; A237-D241 HydrophobicContact CB-CB 4.11Å
238S92.9Very high88.9Confident52 Ų5255.7 Ų55.736%0.36430%0.297SS..  trans-68.4159.2169.479.70000110.2K240 D241 F242S238-K240 PolarHBondContact O-N 2.85Å; S238-K240 PolarHBondContact OG-N 2.82Å; S238-D241 VanDerWaalsContact CB-OD2 3.23Å; S238-D241 WeakPolarHBondContact CB-OD2 3.22Å; S238-D241 PolarHBondContact N-OD2 3.13Å; S238-D241 PolarHBondContact O-N 2.93Å; S238-D241 VanDerWaalsContact O-N 3.12Å; S238-D241 PolarHBondContact OG-N 2.68Å; S238-D241 PolarHBondContact OG-OD2 3.36Å; S238-F242 PolarHBondContact O-N 2.77Å; S238-F242 VanDerWaalsContact O-N 3.07Å
239W92.4Very high86.7Confident84 Ų8455.7 Ų55.732%0.31830%0.304SS..Hα-helixtrans-61.5-28.7174.668.7-102.4000112.1F242 V243 C393 P394 H395W239-F242 PolarHBondContact O-N 2.83Å; W239-V243 HydrophobicContact CE3-CG2 4.17Å; W239-V243 WeakPolarHBondContact O-CB 3.37Å; W239-V243 WeakPolarHBondContact O-CG2 3.48Å; W239-V243 PolarHBondContact O-N 3.01Å; W239-C393 HydrophobicContact CB-CB 3.65Å; W239-P394 HydrophobicContact CD2-CG 4.38Å; W239-P394 HydrophobicContact CE3-CG 4.35Å; W239-P394 HydrophobicContact CH2-CG 4.24Å; W239-P394 HydrophobicContact CZ2-CG 4.26Å; W239-P394 HydrophobicContact CZ3-CG 4.29Å; W239-H395 AromaticContact CZ3-CD2 3.77Å; W239-H395 AromaticContact CZ3-NE2 3.71Å
240K93.5Very high84.2Confident132 Ų13262.6 Ų62.657%0.57433%0.332SS*.Hα-helixtrans-65.2-42.3174.4-67.5-170.5174-168.50111.4S238 V243 K244S238-K240 PolarHBondContact O-N 2.85Å; S238-K240 PolarHBondContact OG-N 2.82Å; K240-V243 PolarHBondContact O-N 3.48Å; K240-K244 WeakPolarHBondContact O-CB 3.31Å; K240-K244 PolarHBondContact O-N 3.24Å
241D91.6Very high81Confident89 Ų8965.4 Ų65.448%0.47635%0.347SS..Hα-helixtrans-67.3-40.2177.5-55.2-55.8000111.5A237 S238 K244 Q245A237-D241 HydrophobicContact CB-CB 4.11Å; S238-D241 VanDerWaalsContact CB-OD2 3.23Å; S238-D241 WeakPolarHBondContact CB-OD2 3.22Å; S238-D241 PolarHBondContact N-OD2 3.13Å; S238-D241 PolarHBondContact O-N 2.93Å; S238-D241 VanDerWaalsContact O-N 3.12Å; S238-D241 PolarHBondContact OG-N 2.68Å; S238-D241 PolarHBondContact OG-OD2 3.36Å; D241-K244 PolarHBondContact O-N 2.78Å; D241-Q245 WeakPolarHBondContact O-CB 3.47Å; D241-Q245 PolarHBondContact O-N 3.18Å
242F92.2Very high78Confident1 Ų171 Ų710%0.00438%0.378CS..Hα-helixtrans-63.8-45174.6176.9-119.7000111.8V162 I186 V233 S238 W239 K244 Q245 V246 F371 L373 H389V162-F242 HydrophobicContact CG1-CZ 4.41Å; I186-F242 HydrophobicContact CD1-CE2 4.13Å; V233-F242 HydrophobicContact CG1-CD2 3.82Å; V233-F242 HydrophobicContact CG1-CE2 3.81Å; V233-F242 HydrophobicContact CG2-CE2 4.2Å; S238-F242 PolarHBondContact O-N 2.77Å; S238-F242 VanDerWaalsContact O-N 3.07Å; W239-F242 PolarHBondContact O-N 2.83Å; F242-K244 VanDerWaalsContact C-N 3.33Å; F242-K244 PolarHBondContact O-N 2.85Å; F242-Q245 WeakPolarHBondContact O-CB 3.45Å; F242-Q245 PolarHBondContact O-N 2.83Å; F242-V246 HydrophobicContact CE2-CG2 4.41Å; F242-V246 HydrophobicContact CZ-CG2 4.38Å; F242-V246 WeakPolarHBondContact O-CG2 3.44Å; F242-V246 PolarHBondContact O-N 3.07Å; F242-F371 HydrophobicContact CD1-CZ 4.49Å; F242-F371 HydrophobicContact CE1-CE2 4.07Å; F242-F371 AromaticContact CE1-CZ 3.89Å; F242-F371 HydrophobicContact CE1-CZ 3.89Å; F242-L373 HydrophobicContact CZ-CD1 3.99Å; F242-H389 HydrophobicContact CD1-CB 4.05Å; F242-H389 AromaticContact CD1-CG 3.95Å; F242-H389 AromaticContact CD1-ND1 3.87Å; F242-H389 HydrophobicContact CE1-CB 4.04Å; F242-H389 AromaticContact CG-CG 3.99Å; F242-H389 AromaticContact CG-ND1 3.75Å
243V91.7Very high75.1Confident25 Ų2573.3 Ų73.315%0.15240%0.404CS..Hα-helixtrans-60.5-40.9172.8161.10000111.6W239 K240 Q245 V246 G247 C368 F371W239-V243 HydrophobicContact CE3-CG2 4.17Å; W239-V243 WeakPolarHBondContact O-CB 3.37Å; W239-V243 WeakPolarHBondContact O-CG2 3.48Å; W239-V243 PolarHBondContact O-N 3.01Å; K240-V243 PolarHBondContact O-N 3.48Å; V243-Q245 VanDerWaalsContact C-N 3.35Å; V243-Q245 PolarHBondContact O-N 3.29Å; V243-V246 WeakPolarHBondContact O-CB 3.27Å; V243-V246 PolarHBondContact O-N 3.15Å; V243-G247 PolarHBondContact O-N 3.35Å; V243-C368 HydrophobicContact CG1-CB 3.94Å; V243-C368 WeakPolarHBondContact CG1-SG 3.33Å; V243-F371 HydrophobicContact CG2-CE1 4.36Å
244K90.6Very high72Confident124 Ų12481.9 Ų81.954%0.53944%0.443SS..Hα-helixtrans-64.2-38.5175.4-170.6172.4-176.81740112K240 D241 F242 G247 N248K240-K244 WeakPolarHBondContact O-CB 3.31Å; K240-K244 PolarHBondContact O-N 3.24Å; D241-K244 PolarHBondContact O-N 2.78Å; F242-K244 VanDerWaalsContact C-N 3.33Å; F242-K244 PolarHBondContact O-N 2.85Å; K244-G247 PolarHBondContact O-N 3.06Å; K244-N248 WeakPolarHBondContact O-CB 3.37Å; K244-N248 VanDerWaalsContact O-CG 3.23Å; K244-N248 PolarHBondContact O-N 2.62Å; K244-N248 PolarHBondContact O-OD1 3.41Å
245Q89.9Confident69.1Low46 Ų4685.8 Ų85.822%0.21546%0.464CS..Hα-helixtrans-62.1-40.9173-172.8174.342.500112V229 W232 D241 F242 V243V229-Q245 HydrophobicContact CG1-CG 4.46Å; W232-Q245 PolarHBondContact O-NE2 3.28Å; D241-Q245 WeakPolarHBondContact O-CB 3.47Å; D241-Q245 PolarHBondContact O-N 3.18Å; F242-Q245 WeakPolarHBondContact O-CB 3.45Å; F242-Q245 PolarHBondContact O-N 2.83Å; V243-Q245 VanDerWaalsContact C-N 3.35Å; V243-Q245 PolarHBondContact O-N 3.29Å
246V87.1Confident66.3Low22 Ų2296.1 Ų96.113%0.13350%0.499CS..Hα-helixtrans-65.8-43.5172.6175.30000111.6V162 T184 I186 F242 V243V162-V246 HydrophobicContact CG1-CG2 4.01Å; V162-V246 HydrophobicContact CG2-CG1 3.72Å; V162-V246 HydrophobicContact CG2-CG2 3.91Å; T184-V246 HydrophobicContact CG2-CG1 4.38Å; I186-V246 HydrophobicContact CD1-CG2 3.88Å; F242-V246 HydrophobicContact CE2-CG2 4.41Å; F242-V246 HydrophobicContact CZ-CG2 4.38Å; F242-V246 WeakPolarHBondContact O-CG2 3.44Å; F242-V246 PolarHBondContact O-N 3.07Å; V243-V246 WeakPolarHBondContact O-CB 3.27Å; V243-V246 PolarHBondContact O-N 3.15Å
247G77.3Confident63.4Low35 Ų3595.7 Ų95.736%0.36151%0.508SS..Hα-helixtrans-71.3-38.6-173.300000114.8V243 K244 G249 K250V243-G247 PolarHBondContact O-N 3.35Å; K244-G247 PolarHBondContact O-N 3.06Å; G247-G249 PolarHBondContact O-N 2.8Å; G247-K250 PolarHBondContact O-N 3.19Å; G247-K250 VanDerWaalsContact O-N 3.13Å
248N60Low60.3Low108 Ų10899.1 Ų99.158%0.57854%0.536SS*.G310 helixtrans-56.8-23.3-177.4-79.94.1000113.9K244 K250K244-N248 WeakPolarHBondContact O-CB 3.37Å; K244-N248 VanDerWaalsContact O-CG 3.23Å; K244-N248 PolarHBondContact O-N 2.62Å; K244-N248 PolarHBondContact O-OD1 3.41Å; N248-K250 PolarHBondContact O-N 3.47Å
249G50.3Low57.1Low26 Ų26102.6 Ų102.627%0.26856%0.557SS.*G310 helixtrans-65.2-12.5177.900000115.6C227 G247 C251C227-G249 WeakPolarHBondContact SG-CA 3.44Å; C227-G249 PolarHBondContact SG-O 2.9Å; G247-G249 PolarHBondContact O-N 2.8Å; G249-C251 VanDerWaalsContact C-N 3.35Å; G249-C251 PolarHBondContact O-N 3.41Å
250K42.7Very low53.9Low164 Ų164103.9 Ų103.971%0.71359%0.586SS**G310 helixtrans-76.7-13.2-179.6-69.5-176.1176.6179.80114.8G247 N248 V252G247-K250 PolarHBondContact O-N 3.19Å; G247-K250 VanDerWaalsContact O-N 3.13Å; N248-K250 PolarHBondContact O-N 3.47Å; K250-V252 PolarHBondContact O-N 2.87Å
251C27.2Very low50.6Low115 Ų115101.2 Ų101.278%0.77760%0.596SS**SBendtrans-94.514.7-161.4-155.90000116.5G249G249-C251 VanDerWaalsContact C-N 3.35Å; G249-C251 PolarHBondContact O-N 3.41Å
252V29.2Very low47.5Very low132 Ų132102.6 Ų102.680%0.861%0.613SS**SBendtrans-135.551.3-175.2-160.70000112.5K250K250-V252 PolarHBondContact O-N 2.87Å
253C28.9Very low44.2Very low124 Ų124108.4 Ų108.484%0.83865%0.653SS**SBendtrans-153.138.8176.9-122.40000115.7
254E26.8Very low41.1Very low190 Ų190117.2 Ų117.289%0.88869%0.69SS**  trans-143.3157.6170.5-124.6150.6-142.600113.1
255D26.8Very low37.9Very low141 Ų141120.4 Ų120.475%0.75470%0.703SS**  trans41.989.9-179.4-78.5-8.8000120.3
256R26Very low34.7Very low251 Ų251129.2 Ų129.295%0.94774%0.735SS**  trans-128.492.5133.5-74-165176.2-163.8-1.7110.8A258R256-A258 PolarHBondContact O-N 2.67Å
257T25.1Very low31.7Very low124 Ų124137.5 Ų137.576%0.76177%0.772SS**PPolyproline II helixtrans-61.5129167.738.90000110.4
258A23.8Very low29Very low96 Ų96147.1 Ų147.179%0.79380%0.797SS**PPolyproline II helixtrans-93.2123.1-17800000111.2R256R256-A258 PolarHBondContact O-N 2.67Å
259P25.8Very low27.2Very low125 Ų125151.2 Ų151.281%0.81281%0.813SS**PPolyproline II helixtrans-73.4139.2169.330.5-33000110.4
260A24.7Very low25.8Very low112 Ų112154.9 Ų154.993%0.92684%0.835SS**PPolyproline II helixtrans-74.3134.5-178.400000112.4
261G25.2Very low24.7Very low75 Ų75156.1 Ų156.177%0.77385%0.845SS**  trans-128.7134.5173.900000110.9
262S25.9Very low24.5Very low119 Ų119156.2 Ų156.283%0.83285%0.847SS**  trans-82.4143.9-161.752.60000115.6
263S22.8Very low24.1Very low123 Ų123159.1 Ų159.186%0.8685%0.852SS**  trans-68.6129.6175.9-57.40000113.1
264K26.1Very low23.8Very low210 Ų210158.1 Ų158.191%0.91385%0.852SS**  trans-123156.2152.1-74.4-172.8177.4178.80109.8
265K24.2Very low23.6Very low190 Ų190155.6 Ų155.683%0.82685%0.845SS**  trans-141.5140.3-154.7-163.9-174.7-171.2176.30111.1
266R23Very low23.5Very low232 Ų232157.8 Ų157.888%0.87585%0.851SS**  trans70.9158.9-178.5-64.6177.2163.6176.5-6.9113.2
267Q23Very low23.4Very low195 Ų195153.8 Ų153.891%0.91184%0.843SS**  cis-113.2-166.413-77.7175.1-69.300114.9
268R21.5Very low23.4Very low237 Ų237157.1 Ų157.189%0.89485%0.849SS**  trans-144.2116-167.6172.3-160.3-171.1-1655107.8
269E21.5Very low23.3Very low195 Ų195155.3 Ų155.391%0.91184%0.84SS**  trans-130.1173.3168.4-68.1-170.714100109.5
270S21Very low23.2Very low103 Ų103158.9 Ų158.972%0.7285%0.846SS**  trans-153.6143.9-154.253.90000115
271M19.9Very low23.1Very low189 Ų189156.6 Ų156.693%0.93183%0.833SS**  trans68.9142.9174.1-57.9169.764.700113
272S23.4Very low22.9Very low118 Ų118161.1 Ų161.183%0.82584%0.839SS**  cis-139.8-174.836.754.90000114.9
273E21.3Very low22.7Very low193 Ų193164.1 Ų164.190%0.90284%0.84SS**  trans-92.2149.8179.1-60.8167.1120.500112.6
274A22.7Very low22.7Very low102 Ų102164 Ų16484%0.84384%0.836SS**  trans-159.7141156.700000110.7
275D21.8Very low22.5Very low137 Ų137160 Ų16073%0.73383%0.829SS**  trans-69.6147.9176.8-91.9-64.9000113.7
276Q25.4Very low22.3Very low188 Ų188159.1 Ų159.188%0.87983%0.833SS**  -165.2148.9111-107.6164.672.900114.9
277Q22.3Very low22.3Very low167 Ų167153.5 Ų153.578%0.7883%0.825SS**  trans-94.6137.9-175.9-57.2162.91.600110.8
278H25.5Very low22.2Very low193 Ų193148.9 Ų148.989%0.89482%0.82SS**  trans-158.6148.3154.3-92.180.9000107.5
279G21.3Very low22.3Very low59 Ų59146.1 Ų146.161%0.60882%0.817SS**  cis165.4-2.8-1.900000116.7
280H24.4Very low22.6Very low200 Ų200139.5 Ų139.593%0.92679%0.792SS**  trans-151.3156.2178.1-75.5-71.8000109.9
281G22Very low22.9Very low64 Ų64139.1 Ų139.166%0.6678%0.779SS**  cis166.161.2-1.600000113
282D22Very low23.4Very low169 Ų169138.5 Ų138.590%0.90477%0.771SS**PPolyproline II helixtrans-70132.6-171.1-70.2-37.2000114.5
283Q21.5Very low23.7Very low182 Ų182136.4 Ų136.485%0.8575%0.751SS**PPolyproline II helixtrans-89.6133.8164.5-66.1-171.7800110.5V285Q283-V285 PolarHBondContact O-N 2.82Å
284P23.5Very low23.8Very low120 Ų120129.2 Ų129.278%0.77973%0.728SS**PPolyproline II helixtrans-77.5118.817830.3-33.3000111.8L286P284-L286 PolarHBondContact O-N 2.92Å
285V22.1Very low24Very low126 Ų126129 Ų12976%0.76472%0.719SS**PPolyproline II helixtrans-66.9128.3168.3176.40000109.5Q283 T287Q283-V285 PolarHBondContact O-N 2.82Å; V285-T287 PolarHBondContact O-N 3.5Å
286L19.8Very low24.2Very low172 Ų172127.8 Ų127.890%0.90172%0.721SS**  trans-75.990.9-177.1-70.8171.2000112.3P284P284-L286 PolarHBondContact O-N 2.92Å
287T21.5Very low24.3Very low115 Ų115125.6 Ų125.671%0.70672%0.716SS**  trans-87.2112169.143.60000111.7V285 E289V285-T287 PolarHBondContact O-N 3.5Å; T287-E289 PolarHBondContact O-N 2.97Å
288A21.4Very low24.5Very low97 Ų97122.3 Ų122.380%0.80270%0.704SS**  trans-75.690173.200000111.2
289E23.8Very low24.3Very low179 Ų179117.1 Ų117.184%0.83670%0.702SS**  trans-75.9120.4172.6-65.9-163.6135.600111.6T287T287-E289 PolarHBondContact O-N 2.97Å
290S27.4Very low24.5Very low56 Ų56123.5 Ų123.539%0.39272%0.716SS.*  trans-64.7144.1164.653.10000110.7F292S290-F292 VanDerWaalsContact C-N 3.34Å; S290-F292 PolarHBondContact O-N 3.21Å
291E29Very low24.4Very low96 Ų96119 Ų11945%0.44971%0.714SS.*  trans-59.581.3-174.1-64.5-165149.700114.4L293 R486E291-L293 PolarHBondContact O-N 3.2Å; E291-R486 IonicContact OE1-CZ 2.78Å; E291-R486 IonicContact OE1-NE 3.23Å; E291-R486 PolarHBondContact OE1-NE 3.41Å; E291-R486 IonicContact OE1-NH2 3.2Å; E291-R486 PolarHBondContact OE1-NH2 2.75Å; E291-R486 IonicContact OE2-NE 2.68Å; E291-R486 IonicContact OE2-NH2 3.67Å
292F29.3Very low24.4Very low175 Ų175120.9 Ų120.977%0.76872%0.723SS**  trans-87.377.1-170.9-146.6-86000112S290 G294S290-F292 VanDerWaalsContact C-N 3.34Å; S290-F292 PolarHBondContact O-N 3.21Å; F292-G294 PolarHBondContact O-N 3.31Å
293L29Very low24.4Very low75 Ų75118.1 Ų118.139%0.39372%0.717SS.*  trans-74.538.2176.9-110.7166.2000113.9E291 M482E291-L293 PolarHBondContact O-N 3.2Å; L293-M482 HydrophobicContact CD1-CB 4.14Å; L293-M482 HydrophobicContact CD2-CG 4.47Å
294G25.3Very low24.5Very low41 Ų41115.6 Ų115.642%0.42372%0.716SS.*  trans-100.766.9173.900000111.7F292 S296F292-G294 PolarHBondContact O-N 3.31Å; G294-S296 PolarHBondContact O-N 2.59Å; G294-S296 VanDerWaalsContact O-N 3.11Å
295C25.2Very low24.5Very low97 Ų97117.6 Ų117.666%0.65572%0.72SS**  trans-84.479-178.4-156.90000111.2D297C295-D297 PolarHBondContact O-N 2.82Å
296S27.1Very low24.5Very low112 Ų112121.4 Ų121.478%0.78373%0.726SS**  trans-75.5101167.3-51.90000109.8G294G294-S296 PolarHBondContact O-N 2.59Å; G294-S296 VanDerWaalsContact O-N 3.11Å
297D26.8Very low24.6Very low142 Ų142119.7 Ų119.776%0.75972%0.718SS**  trans-129.6145.5170.2-150.4-12000110.8C295C295-D297 PolarHBondContact O-N 2.82Å
298N26.1Very low24.8Very low99 Ų99121.7 Ų121.753%0.52972%0.724SS.*  trans-90.3118.8-170.8-64.3-89.1000110.6Q300N298-Q300 PolarHBondContact O-N 3.1Å; N298-Q300 VanDerWaalsContact O-N 3.14Å
299G22.9Very low24.8Very low83 Ų83123.2 Ų123.286%0.85672%0.719SS**  trans-60.6114.6168.100000111.5
300Q23.6Very low24.8Very low193 Ų193121.5 Ų121.590%0.90272%0.715SS**PPolyproline II helixtrans-81119.6160.7-71.7-176.8-1400108.1N298N298-Q300 PolarHBondContact O-N 3.1Å; N298-Q300 VanDerWaalsContact O-N 3.14Å
301A23Very low24.6Very low106 Ų106124 Ų12488%0.87673%0.729SS**PPolyproline II helixtrans-77.2126.6171.700000109.6
302A21.9Very low24.2Very low104 Ų104124.9 Ų124.986%0.8674%0.744SS**PPolyproline II helixtrans-86.7132.5170.900000110.2
303S22.3Very low23.8Very low111 Ų111122.1 Ų122.178%0.77674%0.742SS**PPolyproline II helixtrans-93.2159.1170470000110.9
304P24.7Very low23.5Very low129 Ų129125.4 Ų125.484%0.83876%0.76SS**PPolyproline II helixtrans-84.2166.6-152.531.7-37.1000116.6
305L22Very low23.4Very low162 Ų162128.2 Ų128.285%0.84877%0.772SS**PPolyproline II helixtrans-51.9150.6-178.1-65.4130.3000115.5
306K23.6Very low23.2Very low205 Ų205132.3 Ų132.389%0.89178%0.779SS**  trans-133147.3142.5-76.8-167.1174-175.20109.6
307N21.9Very low22.9Very low137 Ų137132.7 Ų132.773%0.73378%0.777SS**  trans-76.1159.6-174.5-55.3-3000112.2
308N24.2Very low22.7Very low157 Ų157131.2 Ų131.284%0.8478%0.778SS**  -165.8155.7114.1-100.99.9000111.3
309D21.9Very low22.5Very low128 Ų128132.2 Ų132.268%0.68479%0.787SS**  trans-88.1155.7-171.6-46.2-89.4000113.5
310N23.9Very low22.4Very low143 Ų143136 Ų13677%0.76578%0.781SS**  171.2119.7109.1-90.9-43.7000115.9
311T22.4Very low22.3Very low110 Ų110135 Ų13568%0.67578%0.775SS**  trans40132.4132.562.40000124.3
312C21.1Very low22.2Very low113 Ų113135.2 Ų135.276%0.76476%0.758SS**  trans72.3151138.4-65.40000119.3
313T21.9Very low22.3Very low118 Ų118136.3 Ų136.372%0.72476%0.757SS**  cis-160171.4-8.111.10000111.5
314N21.7Very low22.3Very low144 Ų144140.7 Ų140.777%0.7776%0.756SS**  trans-16.3159.2157.7-48.2-18.3000118.2
315S22.6Very low22.1Very low99 Ų99139.6 Ų139.669%0.69275%0.752SS**  cis-172.415144.8-42.80000115.1
316F21Very low22Very low183 Ų183136.6 Ų136.680%0.80374%0.744SS**  trans61.4118.7137.7-81.8-119000122.1
317T22Very low22Very low120 Ų120132.1 Ų132.174%0.73674%0.739SS**  60145.1102.273.50000116.9
318S21.8Very low21.9Very low111 Ų111132.7 Ų132.778%0.77674%0.741SS**  cis-160.8-168.314.8-1470000109.1
319V22.3Very low21.7Very low120 Ų120131.6 Ų131.673%0.72773%0.734SS**  cis-155.2-168.51179.20000113
320K21.7Very low21.7Very low164 Ų164134.5 Ų134.571%0.71374%0.741SS**  trans-63.1175.8178.6-52.1165.1-171.5176.70115.3
321H21Very low22.1Very low170 Ų170132.7 Ų132.779%0.78774%0.737SS**  cis-159.215937.3-125.2-75.1000116.3
322E19.6Very low22.1Very low112 Ų112137.6 Ų137.652%0.52375%0.749SS.*  trans-76168.1166.8-134.7-160.3-134.800111.6R324E322-R324 IonicContact OE1-CZ 3.2Å; E322-R324 VanDerWaalsContact OE1-CZ 3.28Å; E322-R324 IonicContact OE1-NE 3.56Å; E322-R324 PolarHBondContact OE1-NE 3.49Å; E322-R324 IonicContact OE1-NH2 3.22Å; E322-R324 PolarHBondContact OE1-NH2 3.44Å; E322-R324 WeakPolarHBondContact OE2-CG 3.47Å; E322-R324 IonicContact OE2-CZ 2.8Å; E322-R324 IonicContact OE2-NE 2.75Å; E322-R324 PolarHBondContact OE2-NE 2.99Å; E322-R324 IonicContact OE2-NH2 2.87Å
323P25.5Very low22.1Very low127 Ų127143.3 Ų143.383%0.82576%0.755SS**  -149.6-164.368.841.4-19.9000116.7
324R20.7Very low22.1Very low203 Ų203145.2 Ų145.277%0.76676%0.76SS**  trans-123154.7-162-47.4159.6-170.9-170.9-4.6114.8E322E322-R324 IonicContact OE1-CZ 3.2Å; E322-R324 VanDerWaalsContact OE1-CZ 3.28Å; E322-R324 IonicContact OE1-NE 3.56Å; E322-R324 PolarHBondContact OE1-NE 3.49Å; E322-R324 IonicContact OE1-NH2 3.22Å; E322-R324 PolarHBondContact OE1-NH2 3.44Å; E322-R324 WeakPolarHBondContact OE2-CG 3.47Å; E322-R324 IonicContact OE2-CZ 2.8Å; E322-R324 IonicContact OE2-NE 2.75Å; E322-R324 PolarHBondContact OE2-NE 2.99Å; E322-R324 IonicContact OE2-NH2 2.87Å
325S21.3Very low22.1Very low106 Ų106143.4 Ų143.474%0.74176%0.757SS**  trans-177.1138.4144.8-1730000108.1
326S20.7Very low22Very low99 Ų99147.9 Ų147.969%0.69276%0.764SS**  cis117.4150.19.687.70000113.2
327S21.9Very low22.1Very low111 Ų111145.6 Ų145.678%0.77676%0.759SS**  trans77.3150.8-176.480.10000118.3
328L20.4Very low22.2Very low148 Ų148148.3 Ų148.378%0.77576%0.763SS**  cis-167145.8-46.6-107.6162.2000110.6
329L21.3Very low22.3Very low134 Ų134147.4 Ų147.470%0.70276%0.762SS**  trans62.4115154.6-56.9166.9000123.3
330F20.1Very low22.2Very low189 Ų189145 Ų14583%0.82976%0.761SS**  trans13.7170.6131.9-55.8-74.3000123.5
331P33.9Very low22.3Very low105 Ų105147.2 Ų147.268%0.68277%0.774SS**  cis-139.7-176.2-49.441.6-25.6000112.9
332K21.2Very low22.2Very low213 Ų213142.5 Ų142.593%0.92677%0.772SS**  trans-174.6164.5143.7-105149.1-169.31730115.9
333R21Very low23.3Very low233 Ų233142.7 Ų142.788%0.87978%0.782SS**  trans-108.4163.6171-60.7173.5172.2177-4.2110.2
334L22.4Very low23.2Very low159 Ų159146.3 Ų146.383%0.83278%0.781SS**  160.1175.5107.2-150.758.9000113.6
335C21.5Very low23.4Very low105 Ų105142.2 Ų142.271%0.70978%0.778SS**  trans-108174.1-157.5-41.90000116.7
336K21.4Very low23.5Very low194 Ų194145.2 Ų145.284%0.84378%0.78SS**  trans-170.8153.5151.6-108.4169.9-178.4-176.20110.6
337I22.2Very low24.2Very low134 Ų134145.6 Ų145.669%0.68778%0.781SS**  cis82.7121.811.2-55.2167.2000113.3
338E23.8Very low24.3Very low178 Ų178148.4 Ų148.483%0.83279%0.786SS**  cis-158.3-171.53.9-130.4170.6-105.700108.4
339A23.6Very low24.4Very low91 Ų91146.8 Ų146.875%0.75279%0.785SS**  cis-162.3-169.8-1.900000107
340G21.9Very low24.6Very low69 Ų69149.7 Ų149.771%0.71180%0.796SS**  cis161.8153.5-8.300000114.3
341Q22.1Very low24.8Very low212 Ų212150 Ų15099%0.99180%0.799SS**  trans77.5158.9163-55.8-174.40.500122.3
342G20.4Very low24.3Very low71 Ų71150.8 Ų150.873%0.73281%0.808SS**  trans-125.3-141.4-173.600000113.9
343P42.9Very low24.5Very low115 Ų115146.2 Ų146.275%0.74780%0.803SS**  cis-143.7-150.64.943.6-20.9000116.1
344Y22.1Very low24.6Very low204 Ų204139.9 Ų139.980%0.879%0.794SS**  trans86.1110.9179.5-66.2-86.4000116.9
345V25Very low24.8Very low116 Ų116139.2 Ų139.270%0.70380%0.797SS**  84.1131.257.9163.70000111.9
346H23.4Very low25Very low169 Ų169141.7 Ų141.778%0.78280%0.798SS**  cis-174.9-176.2-11.1-108.7-42.4000108
347P36.8Very low25.2Very low108 Ų108138.6 Ų138.670%0.70180%0.795SS**  cis-130173.7-29.740.3-25.4000113.9
348L23Very low25.3Very low170 Ų170137.9 Ų137.989%0.8980%0.796SS**  trans-167.8162.9146-112.1167000111.8
349C22.9Very low25.3Very low113 Ų113134.9 Ų134.976%0.76479%0.79SS**  trans-78.7147.4-157.9-49.80000116.5
350Q24.5Very low25.4Very low196 Ų196135.1 Ų135.192%0.91679%0.785SS**  trans-146.1125.1148-103.9-178.4-5.900109.1
351E25.3Very low25.6Very low194 Ų194137.5 Ų137.591%0.90779%0.788SS**  trans-104.7155.5171.6-73-172.1138.300111
352S23.1Very low26.1Very low122 Ų122132.8 Ų132.885%0.85377%0.773SS**  trans-78.3143.9178.2530000112.6
353S24.9Very low26.7Very low118 Ų118137.6 Ų137.683%0.82578%0.777SS**  trans-122129.7151.760.40000110.6
354S24Very low26.4Very low99 Ų99141.7 Ų141.769%0.69279%0.786SS**  trans-80.7130.9173.943.60000110.2E356S354-E356 VanDerWaalsContact C-N 3.3Å; S354-E356 PolarHBondContact O-N 2.94Å
355T26.1Very low27.3Very low146 Ų146135.2 Ų135.290%0.89678%0.782SS**  trans-73.986.2168.8-44.20000109.3V357T355-V357 PolarHBondContact O-N 3.21Å
356E24.8Very low28.2Very low156 Ų156138.1 Ų138.173%0.72979%0.787SS**  trans-61.3131.2173.6-66.3-168.5138.600110.3S354 V358S354-E356 VanDerWaalsContact C-N 3.3Å; S354-E356 PolarHBondContact O-N 2.94Å; E356-V358 PolarHBondContact O-N 3.5Å; E356-V358 VanDerWaalsContact O-N 3.13Å
357V26Very low29.9Very low129 Ų129138.6 Ų138.678%0.78279%0.79SS**  trans-74.7102.9167.31780000106.7T355 V359T355-V357 PolarHBondContact O-N 3.21Å; V357-V359 VanDerWaalsContact C-N 3.29Å; V357-V359 HydrophobicContact CG1-CG2 4.21Å; V357-V359 PolarHBondContact O-N 2.85Å
358V24.3Very low31.5Very low119 Ų119135 Ų13572%0.72177%0.767SS**  trans-65.991.3174.8-178.30000108.9E356 C360E356-V358 PolarHBondContact O-N 3.5Å; E356-V358 VanDerWaalsContact O-N 3.13Å; V358-C360 PolarHBondContact O-N 3.49Å; V358-C360 VanDerWaalsContact O-N 3.09Å
359V24.7Very low34.5Very low116 Ų116130.6 Ų130.670%0.70375%0.749SS**  trans-75.991.9168.6-179.20000107.1V357 P361V357-V359 VanDerWaalsContact C-N 3.29Å; V357-V359 HydrophobicContact CG1-CG2 4.21Å; V357-V359 PolarHBondContact O-N 2.85Å; V359-P361 WeakPolarHBondContact O-CD 3.38Å
360C24.8Very low37.9Very low95 Ų95128.6 Ų128.664%0.64273%0.73SS**  trans-54.7125.3165.9-61.40000108.6V358 V362V358-C360 PolarHBondContact O-N 3.49Å; V358-C360 VanDerWaalsContact O-N 3.09Å; C360-V362 PolarHBondContact O-N 3.49Å
361P27.2Very low41.3Very low119 Ų119119.5 Ų119.577%0.77369%0.688SS**  trans-58.3125.2169.6-22.133.7000108.9V359 E363V359-P361 WeakPolarHBondContact O-CD 3.38Å; P361-E363 PolarHBondContact O-N 3.03Å
362V32.7Very low44.8Very low113 Ų113110.2 Ų110.269%0.68564%0.644SS**  trans-76.5114.3165.6179.70000105.7C360 E364C360-V362 PolarHBondContact O-N 3.49Å; V362-E364 PolarHBondContact O-N 3.35Å
363E32.9Very low48.3Very low172 Ų172104.4 Ų104.480%0.80460%0.604SS**  trans-59.5133.1-178-63.9-172.2152.100111P361 G365P361-E363 PolarHBondContact O-N 3.03Å; E363-G365 PolarHBondContact O-N 3.24Å
364E36.6Very low51.8Low202 Ų20298.8 Ų98.894%0.94457%0.565SS**THydrogen-bonded Turntrans-7472.8177.7-65.9-162.812100110.7V362V362-E364 PolarHBondContact O-N 3.35Å
365G40.5Very low55.3Low68 Ų6894.1 Ų94.170%0.70153%0.532SS*.THydrogen-bonded Turntrans-171.3-12.2179.500000115.9E363 E367E363-G365 PolarHBondContact O-N 3.24Å; G365-E367 PolarHBondContact O-N 3.45Å
366Q44.3Very low58.6Low177 Ų17787.5 Ų87.583%0.82749%0.491SS*.  trans-80.7105.8179.7-166.4164.452.300111.5C368Q366-C368 PolarHBondContact O-N 3.31Å
367E59.5Low61.8Low179 Ų17982.5 Ų82.584%0.83647%0.467SS*.PPolyproline II helixtrans-55.3130.7174.9-64.6-172.9141.200111.4G365 P369G365-E367 PolarHBondContact O-N 3.45Å; E367-P369 WeakPolarHBondContact O-CD 3.08Å
368C70.1Confident65Low32 Ų3276.3 Ų76.322%0.21643%0.43CS..PPolyproline II helixtrans-74.6124.2171.2179.70000108.9V243 Q366 D370 H395V243-C368 HydrophobicContact CG1-CB 3.94Å; V243-C368 WeakPolarHBondContact CG1-SG 3.33Å; Q366-C368 PolarHBondContact O-N 3.31Å; C368-D370 PolarHBondContact O-N 3.06Å; C368-H395 PolarHBondContact O-CE1 2.61Å; C368-H395 PolarHBondContact O-ND1 3.06Å; C368-H395 VanDerWaalsContact O-ND1 3.09Å
369P85.8Confident68.2Low78 Ų7873.3 Ų73.351%0.50641%0.413SS..PPolyproline II helixtrans-67.9134.4177.528.1-34.5000110.5E367E367-P369 WeakPolarHBondContact O-CD 3.08Å
370D93.9Very high71.5Confident71 Ų7167.9 Ų67.938%0.3838%0.381SS..PPolyproline II helixtrans-54.9143.7175.1-81.5-10000112.6C158 S160 C368 H395 R397C158-D370 PolarHBondContact SG-O 3.43Å; S160-D370 WeakPolarHBondContact CB-O 3.39Å; C368-D370 PolarHBondContact O-N 3.06Å; D370-H395 WeakPolarHBondContact CA-O 3.47Å; D370-H395 VanDerWaalsContact OD1-CA 3.25Å; D370-H395 WeakPolarHBondContact OD1-CA 3.46Å; D370-H395 IonicContact OD1-CG 3.59Å; D370-H395 IonicContact OD1-ND1 3.32Å; D370-H395 PolarHBondContact OD1-ND1 3.35Å; D370-R397 HydrophobicContact CB-CG 3.71Å; D370-R397 VanDerWaalsContact CG-CD 3.48Å; D370-R397 WeakPolarHBondContact OD2-CD 3.48Å; D370-R397 IonicContact OD2-NH1 3.88Å
371F96.1Very high74.8Confident4 Ų464.7 Ų64.72%0.01836%0.358CS..EExtended strand (participates in β ladder)trans-143.8158.8-177.462.7-85.1000114.6C158 S160 V162 F242 V243 H395 V396 R397C158-F371 VanDerWaalsContact SG-C 3.55Å; C158-F371 WeakPolarHBondContact SG-CA 3.2Å; C158-F371 PolarHBondContact SG-N 3.15Å; C158-F371 VanDerWaalsContact SG-N 3.43Å; S160-F371 WeakPolarHBondContact O-CA 3.49Å; V162-F371 HydrophobicContact CB-CD2 3.85Å; V162-F371 HydrophobicContact CB-CE2 3.95Å; V162-F371 HydrophobicContact CG2-CB 4.5Å; V162-F371 HydrophobicContact CG2-CD2 3.37Å; V162-F371 HydrophobicContact CG2-CE2 3.56Å; V162-F371 HydrophobicContact CG2-CG 4.01Å; V162-F371 HydrophobicContact CG2-CZ 4.36Å; F242-F371 HydrophobicContact CD1-CZ 4.49Å; F242-F371 HydrophobicContact CE1-CE2 4.07Å; F242-F371 AromaticContact CE1-CZ 3.89Å; F242-F371 HydrophobicContact CE1-CZ 3.89Å; V243-F371 HydrophobicContact CG2-CE1 4.36Å; F371-H395 HydrophobicContact CD1-CB 4.18Å; F371-H395 HydrophobicContact CE1-CB 3.97Å; F371-H395 PolarHBondContact N-O 2.99Å; F371-V396 HydrophobicContact CD2-CG2 4.34Å; F371-V396 HydrophobicContact CE1-CG2 4.27Å; F371-V396 HydrophobicContact CE2-CG2 3.66Å; F371-V396 HydrophobicContact CZ-CG2 3.62Å; F371-V396 CarbonylContact O-C 3.58Å; F371-V396 WeakPolarHBondContact O-CA 3.48Å; F371-R397 PolarHBondContact O-N 3.39Å
372I97.9Very high78Confident0 Ų061 Ų610%033%0.331CS..EExtended strand (participates in β ladder)trans-93.3134.8167.5-58.5-60.2000109.6V149 L152 T156 C158 S160 V161 V162 R397V149-I372 HydrophobicContact CG1-CG2 4.46Å; L152-I372 HydrophobicContact CB-CD1 4.27Å; L152-I372 HydrophobicContact CB-CG1 4.46Å; L152-I372 HydrophobicContact CB-CG2 4.35Å; L152-I372 HydrophobicContact CD2-CG2 4.14Å; T156-I372 HydrophobicContact CG2-CD1 4.43Å; C158-I372 HydrophobicContact CB-CD1 4.4Å; C158-I372 HydrophobicContact CB-CG1 4.32Å; S160-I372 PolarHBondContact O-N 3.11Å; V161-I372 CarbonylContact C-O 3.44Å; V161-I372 VanDerWaalsContact CA-O 3.29Å; V161-I372 WeakPolarHBondContact CA-O 2.87Å; V161-I372 HydrophobicContact CG2-CB 4.38Å; V162-I372 PolarHBondContact N-O 3.45Å; I372-R397 HydrophobicContact CD1-CB 3.99Å
373L97.9Very high81Confident0 Ų055.6 Ų55.60%030%0.299CS..EExtended strand (participates in β ladder)trans-97.5133.1176.6-172.462000110.5V162 V164 F242 L386 F390 V396 G398 I399 T400V162-L373 HydrophobicContact CB-CD1 4.07Å; V162-L373 HydrophobicContact CG1-CD1 4.05Å; V164-L373 HydrophobicContact CG2-CD1 3.75Å; F242-L373 HydrophobicContact CZ-CD1 3.99Å; L373-L386 HydrophobicContact CD1-CD2 3.91Å; L373-L386 HydrophobicContact CD2-CB 4.13Å; L373-L386 HydrophobicContact CD2-CD2 3.87Å; L373-L386 WeakPolarHBondContact CD2-O 3.32Å; L373-L386 HydrophobicContact CG-CD2 3.99Å; L373-F390 HydrophobicContact CD2-CB 4.33Å; L373-V396 HydrophobicContact CB-CG1 3.58Å; L373-V396 HydrophobicContact CD2-CG1 4.42Å; L373-G398 PolarHBondContact N-O 2.78Å; L373-I399 HydrophobicContact CB-CB 4.5Å; L373-I399 HydrophobicContact CB-CG1 4.34Å; L373-I399 HydrophobicContact CD2-CD1 4.22Å; L373-I399 CarbonylContact O-C 3.57Å; L373-I399 VanDerWaalsContact O-CA 3.22Å; L373-I399 WeakPolarHBondContact O-CA 3.42Å; L373-T400 PolarHBondContact O-N 3.24Å
374T98.4Very high84Confident0 Ų047.4 Ų47.40%026%0.261CS..EExtended strand (participates in β ladder)trans-136.3153.3175.6-173.90000112.2V149 V161 V162 D163 V164 L171 L175 T400V149-T374 HydrophobicContact CG2-CG2 4.48Å; V161-T374 HydrophobicContact CG1-CG2 3.7Å; V162-T374 PolarHBondContact O-N 3.02Å; D163-T374 HydrophobicContact CB-CG2 3.85Å; V164-T374 PolarHBondContact N-O 2.81Å; L171-T374 HydrophobicContact CD2-CG2 4.38Å; L175-T374 HydrophobicContact CD1-CG2 4.34Å; T374-T400 VanDerWaalsContact CA-O 3.32Å; T374-T400 WeakPolarHBondContact CA-O 3.31Å; T374-T400 WeakPolarHBondContact CB-OG1 3.3Å; T374-T400 PolarHBondContact OG1-O 3.19Å; T374-T400 PolarHBondContact OG1-OG1 2.89Å; T374-T400 VanDerWaalsContact OG1-OG1 3.12Å
375G97.1Very high86.9Confident0 Ų038.1 Ų38.10%022%0.217CC..EExtended strand (participates in β ladder)trans-151107.8173.300000111.3T400 V402G375-T400 PolarHBondContact N-O 3.25Å; G375-T400 VanDerWaalsContact N-O 3.15Å; G375-V402 PolarHBondContact O-N 2.92Å
376L94.8Very high89.6Confident8 Ų834.9 Ų34.94%0.04218%0.184CC..EExtended strand (participates in β ladder)trans-92.1108.3177.1177.154.8000110.5E141 I142 L145 L171 V402 F589E141-L376 HydrophobicContact CB-CD1 4.1Å; E141-L376 HydrophobicContact CB-CD2 4.27Å; I142-L376 HydrophobicContact CG1-CD2 4Å; L145-L376 HydrophobicContact CD2-CB 3.76Å; L145-L376 HydrophobicContact CD2-CD1 3.89Å; L145-L376 HydrophobicContact CD2-CD2 4.45Å; L145-L376 HydrophobicContact CD2-CG 4.21Å; L171-L376 HydrophobicContact CB-CD2 4.27Å; L171-L376 HydrophobicContact CD2-CB 3.8Å; L171-L376 HydrophobicContact CD2-CD2 4.19Å; L376-V402 HydrophobicContact CD1-CB 4.35Å; L376-V402 HydrophobicContact CD1-CG1 4.38Å; L376-V402 HydrophobicContact CD1-CG2 4.11Å; L376-F589 HydrophobicContact CD1-CE2 4.45Å; L376-F589 HydrophobicContact CD1-CZ 4.13Å
377H92.9Very high92.1Very high50 Ų5026.5 Ų26.523%0.23115%0.145CC..EExtended strand (participates in β ladder)trans69.953-166.5-56.1-71.6000112.8E141 C379 V402 C404E141-H377 IonicContact OE1-CE1 3.79Å; E141-H377 PolarHBondContact OE1-CE1 2.79Å; E141-H377 IonicContact OE1-NE2 2.97Å; E141-H377 PolarHBondContact OE1-NE2 2.88Å; E141-H377 IonicContact OE2-CD2 3.94Å; E141-H377 IonicContact OE2-CE1 2.85Å; E141-H377 IonicContact OE2-NE2 3.89Å; E141-H377 PolarHBondContact OE2-NE2 2.92Å; H377-C379 VanDerWaalsContact C-N 3.28Å; H377-C379 PolarHBondContact O-N 2.93Å; H377-C379 PolarHBondContact O-SG 3.21Å; H377-V402 CarbonylContact C-O 3.58Å; H377-V402 WeakPolarHBondContact CA-O 3.23Å; H377-V402 PolarHBondContact N-O 3.21Å; H377-C404 VanDerWaalsContact CA-SG 3.54Å; H377-C404 HydrophobicContact CB-CB 4.45Å; H377-C404 VanDerWaalsContact CB-SG 3.59Å
378A91.8Very high93.9Very high0 Ų018.6 Ų18.60%011%0.107CC..EExtended strand (participates in β ladder)trans-62.887.3169.200000110.2L382 L386 V402A378-L382 HydrophobicContact CB-CG 4.29Å; A378-L386 HydrophobicContact CB-CD1 4.12Å; A378-V402 PolarHBondContact N-O 2.61Å
379C92.5Very high95.1Very high55 Ų5517.2 Ų17.237%0.37210%0.098SC..  trans-71.9132.3-172.7-69.40000112.1H377 D381 L382 C405H377-C379 VanDerWaalsContact C-N 3.28Å; H377-C379 PolarHBondContact O-N 2.93Å; H377-C379 PolarHBondContact O-SG 3.21Å; C379-D381 PolarHBondContact O-N 3.41Å; C379-L382 VanDerWaalsContact O-CB 3.32Å; C379-L382 WeakPolarHBondContact O-CB 3.35Å; C379-L382 PolarHBondContact O-N 3.43Å; C379-L382 VanDerWaalsContact O-N 3.15Å; C379-C405 HydrophobicContact CB-CB 4.15Å
380G93.5Very high95.7Very high3 Ų313.5 Ų13.53%0.0317%0.073CC..THydrogen-bonded Turntrans55-133.5175.800000112.6L382 S383 C405G380-L382 PolarHBondContact O-N 3.14Å; G380-L382 VanDerWaalsContact O-N 3.14Å; G380-S383 PolarHBondContact O-N 3.3Å; G380-S383 PolarHBondContact O-OG 3.44Å; G380-C405 PolarHBondContact N-O 3.42Å
381D94.8Very high95.8Very high28 Ų2811.8 Ų11.815%0.157%0.066CC..THydrogen-bonded Turntrans-61-17.9-179.9-74.415.7000114.2C379 S383 A384 T385 I409 T410 G439C379-D381 PolarHBondContact O-N 3.41Å; D381-S383 PolarHBondContact O-N 2.89Å; D381-S383 VanDerWaalsContact O-N 3.15Å; D381-A384 CarbonylContact O-C 3.58Å; D381-A384 WeakPolarHBondContact O-CA 3.33Å; D381-A384 WeakPolarHBondContact O-CB 3.48Å; D381-A384 PolarHBondContact O-N 2.88Å; D381-T385 PolarHBondContact O-N 3.27Å; D381-T385 PolarHBondContact O-OG1 2.85Å; D381-I409 VanDerWaalsContact OD1-CA 3.27Å; D381-I409 WeakPolarHBondContact OD1-CA 3.4Å; D381-T410 PolarHBondContact OD1-N 3.36Å; D381-T410 PolarHBondContact OD1-OG1 3.21Å; D381-T410 WeakPolarHBondContact OD2-CB 3.14Å; D381-T410 WeakPolarHBondContact OD2-CG2 3.4Å; D381-T410 PolarHBondContact OD2-OG1 3.17Å; D381-G439 WeakPolarHBondContact OD1-CA 3.27Å
382L94.7Very high95.7Very high40 Ų4014.4 Ų14.421%0.2099%0.085CC..Hα-helixtrans-57-33.7175.3-176.856.3000111.4V164 A378 C379 G380 A384 T385 L386V164-L382 HydrophobicContact CG1-CD1 3.88Å; A378-L382 HydrophobicContact CB-CG 4.29Å; C379-L382 VanDerWaalsContact O-CB 3.32Å; C379-L382 WeakPolarHBondContact O-CB 3.35Å; C379-L382 PolarHBondContact O-N 3.43Å; C379-L382 VanDerWaalsContact O-N 3.15Å; G380-L382 PolarHBondContact O-N 3.14Å; G380-L382 VanDerWaalsContact O-N 3.14Å; L382-A384 VanDerWaalsContact C-N 3.29Å; L382-A384 PolarHBondContact O-N 2.94Å; L382-T385 HydrophobicContact CD1-CG2 4.45Å; L382-T385 PolarHBondContact O-N 3.47Å; L382-L386 HydrophobicContact CD1-CD1 4.4Å; L382-L386 HydrophobicContact CD1-CD2 4.4Å; L382-L386 HydrophobicContact CD1-CG 4.1Å; L382-L386 HydrophobicContact CG-CD1 4.24Å; L382-L386 HydrophobicContact CG-CG 4.41Å; L382-L386 VanDerWaalsContact O-CG 3.28Å; L382-L386 WeakPolarHBondContact O-CG 3.17Å; L382-L386 PolarHBondContact O-N 3.16Å
383S95Very high95.6Very high1 Ų114.4 Ų14.41%0.0079%0.085CC..Hα-helixtrans-63-32.2173.764.20000113.5G380 D381 L387 R572G380-S383 PolarHBondContact O-N 3.3Å; G380-S383 PolarHBondContact O-OG 3.44Å; D381-S383 PolarHBondContact O-N 2.89Å; D381-S383 VanDerWaalsContact O-N 3.15Å; S383-L387 WeakPolarHBondContact O-CD1 3.09Å; S383-L387 WeakPolarHBondContact O-CG 3.41Å; S383-R572 PolarHBondContact OG-NH2 3.47Å
384A96.5Very high95.4Very high0 Ų017.4 Ų17.40%010%0.104CC..Hα-helixtrans-81.7-41174.700000111.9D381 L382 L386 L387 R388 M442D381-A384 CarbonylContact O-C 3.58Å; D381-A384 WeakPolarHBondContact O-CA 3.33Å; D381-A384 WeakPolarHBondContact O-CB 3.48Å; D381-A384 PolarHBondContact O-N 2.88Å; L382-A384 VanDerWaalsContact C-N 3.29Å; L382-A384 PolarHBondContact O-N 2.94Å; A384-L386 VanDerWaalsContact C-N 3.31Å; A384-L386 PolarHBondContact O-N 3.41Å; A384-L387 PolarHBondContact O-N 3.35Å; A384-L387 VanDerWaalsContact O-N 3.13Å; A384-R388 WeakPolarHBondContact O-CG 3.45Å; A384-R388 PolarHBondContact O-N 2.96Å; A384-M442 HydrophobicContact CB-CE 3.84Å; A384-M442 HydrophobicContact CB-CG 4.25Å; A384-M442 HydrophobicContact CB-SD 3.53Å; A384-M442 VanDerWaalsContact CB-SD 3.53Å
385T95.9Very high95.2Very high6 Ų619 Ų194%0.03711%0.112CC..Hα-helixtrans-54.2-44.4173.8-61.80000112.1V233 P235 D381 L382 R388 H389V233-T385 HydrophobicContact CB-CG2 4.25Å; V233-T385 HydrophobicContact CG1-CG2 3.69Å; P235-T385 HydrophobicContact CB-CG2 4.28Å; D381-T385 PolarHBondContact O-N 3.27Å; D381-T385 PolarHBondContact O-OG1 2.85Å; L382-T385 HydrophobicContact CD1-CG2 4.45Å; L382-T385 PolarHBondContact O-N 3.47Å; T385-R388 PolarHBondContact O-N 3.29Å; T385-H389 PolarHBondContact O-CD2 2.81Å; T385-H389 PolarHBondContact O-N 3.29Å
386L97.4Very high95.2Very high1 Ų119 Ų191%0.00511%0.112CC..Hα-helixtrans-68.3-34.9178.2-65172.8000112.5V164 L373 A378 L382 A384 F390 I399V164-L386 HydrophobicContact CB-CD2 3.62Å; V164-L386 HydrophobicContact CG1-CD2 3.99Å; V164-L386 HydrophobicContact CG2-CD2 3.65Å; L373-L386 HydrophobicContact CD1-CD2 3.91Å; L373-L386 HydrophobicContact CD2-CB 4.13Å; L373-L386 HydrophobicContact CD2-CD2 3.87Å; L373-L386 WeakPolarHBondContact CD2-O 3.32Å; L373-L386 HydrophobicContact CG-CD2 3.99Å; A378-L386 HydrophobicContact CB-CD1 4.12Å; L382-L386 HydrophobicContact CD1-CD1 4.4Å; L382-L386 HydrophobicContact CD1-CD2 4.4Å; L382-L386 HydrophobicContact CD1-CG 4.1Å; L382-L386 HydrophobicContact CG-CD1 4.24Å; L382-L386 HydrophobicContact CG-CG 4.41Å; L382-L386 VanDerWaalsContact O-CG 3.28Å; L382-L386 WeakPolarHBondContact O-CG 3.17Å; L382-L386 PolarHBondContact O-N 3.16Å; A384-L386 VanDerWaalsContact C-N 3.31Å; A384-L386 PolarHBondContact O-N 3.41Å; L386-F390 WeakPolarHBondContact O-CB 3.3Å; L386-F390 PolarHBondContact O-N 2.85Å; L386-I399 HydrophobicContact CB-CD1 4.01Å
387L97.8Very high95.2Very high0 Ų019.8 Ų19.80%011%0.114CC..Hα-helixtrans-69.8-37.8174.7-71.1167.5000112S383 A384 V391 I399 M442 R572 Y575 L576 L600S383-L387 WeakPolarHBondContact O-CD1 3.09Å; S383-L387 WeakPolarHBondContact O-CG 3.41Å; A384-L387 PolarHBondContact O-N 3.35Å; A384-L387 VanDerWaalsContact O-N 3.13Å; L387-V391 WeakPolarHBondContact O-CG2 3.35Å; L387-V391 PolarHBondContact O-N 2.98Å; L387-I399 HydrophobicContact CD2-CD1 4.21Å; L387-M442 HydrophobicContact CB-CE 3.95Å; L387-M442 HydrophobicContact CB-SD 4.33Å; L387-M442 HydrophobicContact CD1-SD 3.8Å; L387-R572 HydrophobicContact CD1-CB 3.66Å; L387-R572 HydrophobicContact CD1-CG 3.57Å; L387-Y575 HydrophobicContact CB-CD1 4.37Å; L387-Y575 HydrophobicContact CB-CE1 4.09Å; L387-L576 HydrophobicContact CD2-CD1 3.75Å; L387-L576 HydrophobicContact CD2-CD2 3.99Å; L387-L576 HydrophobicContact CD2-CG 4.03Å; L387-L600 HydrophobicContact CD2-CD1 4.47Å; L387-L600 HydrophobicContact CD2-CD2 3.96Å
388R96.8Very high95.4Very high14 Ų1417.4 Ų17.45%0.05310%0.103CC..Hα-helixtrans-60.5-52.2173-73.6167.5172.6135.210.8111.6A384 T385 V391 S392 E437 F438 M442A384-R388 WeakPolarHBondContact O-CG 3.45Å; A384-R388 PolarHBondContact O-N 2.96Å; T385-R388 PolarHBondContact O-N 3.29Å; R388-V391 PolarHBondContact O-N 3.14Å; R388-S392 WeakPolarHBondContact O-CB 3.47Å; R388-S392 PolarHBondContact O-N 3.18Å; R388-S392 PolarHBondContact O-OG 3.43Å; R388-S392 VanDerWaalsContact O-OG 3.13Å; R388-E437 VanDerWaalsContact CZ-CD 3.43Å; R388-E437 IonicContact CZ-OE1 2.74Å; R388-E437 IonicContact CZ-OE2 3.76Å; R388-E437 IonicContact NE-OE1 3.69Å; R388-E437 PolarHBondContact NE-OE1 3.44Å; R388-E437 IonicContact NE-OE2 2.67Å; R388-E437 PolarHBondContact NE-OE2 3.49Å; R388-E437 PolarHBondContact NH1-O 3.29Å; R388-E437 VanDerWaalsContact NH2-CG 3.33Å; R388-E437 PolarHBondContact NH2-O 3.42Å; R388-E437 VanDerWaalsContact NH2-O 3.07Å; R388-E437 IonicContact NH2-OE1 3.49Å; R388-E437 PolarHBondContact NH2-OE1 3.31Å; R388-E437 IonicContact NH2-OE2 2.68Å; R388-F438 PolarHBondContact NH2-O 3.07Å; R388-M442 HydrophobicContact CG-CE 4.15Å
389H96.5Very high95.7Very high2 Ų217.4 Ų17.41%0.00910%0.103CC..Hα-helixtrans-67.1-35.8178-79-59.2000113.1N234 F242 T385 C393N234-H389 PolarHBondContact O-NE2 2.79Å; F242-H389 HydrophobicContact CD1-CB 4.05Å; F242-H389 AromaticContact CD1-CG 3.95Å; F242-H389 AromaticContact CD1-ND1 3.87Å; F242-H389 HydrophobicContact CE1-CB 4.04Å; F242-H389 AromaticContact CG-CG 3.99Å; F242-H389 AromaticContact CG-ND1 3.75Å; T385-H389 PolarHBondContact O-CD2 2.81Å; T385-H389 PolarHBondContact O-N 3.29Å; H389-C393 WeakPolarHBondContact O-CB 3.46Å; H389-C393 PolarHBondContact O-N 2.88Å
390F97.4Very high96Very high0 Ų014.8 Ų14.80%09%0.085CC..Hα-helixtrans-61.1-43.7170.6169.3-120.3000111.8L373 L386 V396 I399 L576 I581 A602 K604L373-F390 HydrophobicContact CD2-CB 4.33Å; L386-F390 WeakPolarHBondContact O-CB 3.3Å; L386-F390 PolarHBondContact O-N 2.85Å; F390-V396 HydrophobicContact CB-CG1 4.48Å; F390-V396 HydrophobicContact CD2-CB 4.08Å; F390-V396 HydrophobicContact CD2-CG1 3.62Å; F390-V396 HydrophobicContact CE2-CG1 4.41Å; F390-I399 HydrophobicContact CB-CB 4.37Å; F390-I399 HydrophobicContact CB-CD1 4.02Å; F390-I399 HydrophobicContact CB-CG2 4.49Å; F390-I399 HydrophobicContact CD1-CB 4.29Å; F390-I399 HydrophobicContact CD1-CG2 3.55Å; F390-I399 HydrophobicContact CD2-CB 4.03Å; F390-I399 HydrophobicContact CD2-CG2 4.01Å; F390-I399 HydrophobicContact CE1-CG2 3.6Å; F390-I399 HydrophobicContact CE2-CB 4.37Å; F390-I399 HydrophobicContact CE2-CG2 4.06Å; F390-I399 HydrophobicContact CG-CB 3.97Å; F390-I399 HydrophobicContact CG-CD1 4.4Å; F390-I399 HydrophobicContact CG-CG2 3.75Å; F390-I399 HydrophobicContact CZ-CG2 3.85Å; F390-L576 HydrophobicContact CD1-CD1 4.49Å; F390-L576 HydrophobicContact CD1-CD2 3.76Å; F390-L576 HydrophobicContact CE1-CD1 4.15Å; F390-L576 HydrophobicContact CE1-CD2 3.84Å; F390-I581 HydrophobicContact CE1-CD1 4Å; F390-I581 HydrophobicContact CE1-CG2 3.84Å; F390-I581 HydrophobicContact CZ-CD1 4.3Å; F390-I581 HydrophobicContact CZ-CG2 3.91Å; F390-A602 HydrophobicContact CE1-CB 3.59Å; F390-A602 HydrophobicContact CZ-CB 3.74Å; F390-K604 HydrophobicContact CE2-CG 3.86Å; F390-K604 HydrophobicContact CZ-CG 4.11Å; F390-K604 WeakPolarHBondContact O-CE 3.47Å; F390-K604 PolarHBondContact O-NZ 3.04Å
391V96.2Very high96.2Very high36 Ų3614.8 Ų14.822%0.2189%0.085CC..Hα-helixtrans-64.2-54.1175167.20000110.9L387 R388 Y575 L576 K579 I581 K604L387-V391 WeakPolarHBondContact O-CG2 3.35Å; L387-V391 PolarHBondContact O-N 2.98Å; R388-V391 PolarHBondContact O-N 3.14Å; V391-Y575 HydrophobicContact CG2-CE1 3.71Å; V391-L576 HydrophobicContact CG2-CD2 3.71Å; V391-K579 HydrophobicContact CG1-CB 4.34Å; V391-K579 HydrophobicContact CG1-CD 4.44Å; V391-K579 HydrophobicContact CG1-CG 3.9Å; V391-K579 HydrophobicContact CG2-CB 4.4Å; V391-K579 HydrophobicContact CG2-CG 4.04Å; V391-I581 HydrophobicContact CG2-CD1 4.18Å; V391-K604 PolarHBondContact O-NZ 2.97Å
392S94.9Very high96.3Very high59 Ų5913.5 Ų13.541%0.4138%0.078SC..Hα-helixtrans-76-30.5-167.268.50000115.2R388R388-S392 WeakPolarHBondContact O-CB 3.47Å; R388-S392 PolarHBondContact O-N 3.18Å; R388-S392 PolarHBondContact O-OG 3.43Å; R388-S392 VanDerWaalsContact O-OG 3.13Å
393C95Very high96.3Very high0 Ų011.7 Ų11.70%07%0.069CC..  trans-86.9123.2-176.9-174.90000111.5W239 H389 H395 V396 K604W239-C393 HydrophobicContact CB-CB 3.65Å; H389-C393 WeakPolarHBondContact O-CB 3.46Å; H389-C393 PolarHBondContact O-N 2.88Å; C393-H395 VanDerWaalsContact C-N 3.28Å; C393-H395 PolarHBondContact O-N 3.07Å; C393-V396 HydrophobicContact CB-CG2 3.74Å; C393-K604 PolarHBondContact O-NZ 3.27Å
394P93.8Very high96.1Very high62 Ų6212.2 Ų12.240%0.4037%0.072SC..THydrogen-bonded Turntrans-62.7-36.4179.324.5-31.8000112.1W239 V396W239-P394 HydrophobicContact CD2-CG 4.38Å; W239-P394 HydrophobicContact CE3-CG 4.35Å; W239-P394 HydrophobicContact CH2-CG 4.24Å; W239-P394 HydrophobicContact CZ2-CG 4.26Å; W239-P394 HydrophobicContact CZ3-CG 4.29Å; P394-V396 VanDerWaalsContact C-N 3.28Å; P394-V396 PolarHBondContact O-N 2.64Å
395H94.6Very high96.1Very high35 Ų3513.6 Ų13.616%0.1628%0.081CC..THydrogen-bonded Turntrans-73-10.2-173.5-56.7-66.5000115.5W239 C368 D370 F371 C393 R397W239-H395 AromaticContact CZ3-CD2 3.77Å; W239-H395 AromaticContact CZ3-NE2 3.71Å; C368-H395 PolarHBondContact O-CE1 2.61Å; C368-H395 PolarHBondContact O-ND1 3.06Å; C368-H395 VanDerWaalsContact O-ND1 3.09Å; D370-H395 WeakPolarHBondContact CA-O 3.47Å; D370-H395 VanDerWaalsContact OD1-CA 3.25Å; D370-H395 WeakPolarHBondContact OD1-CA 3.46Å; D370-H395 IonicContact OD1-CG 3.59Å; D370-H395 IonicContact OD1-ND1 3.32Å; D370-H395 PolarHBondContact OD1-ND1 3.35Å; F371-H395 HydrophobicContact CD1-CB 4.18Å; F371-H395 HydrophobicContact CE1-CB 3.97Å; F371-H395 PolarHBondContact N-O 2.99Å; C393-H395 VanDerWaalsContact C-N 3.28Å; C393-H395 PolarHBondContact O-N 3.07Å; H395-R397 PolarHBondContact O-N 3.05Å
396V95.9Very high96Very high0 Ų013.4 Ų13.40%08%0.08CC..EExtended strand (participates in β ladder)trans-84.598.7178.4-168.20000109.8F371 L373 F390 C393 P394 G398 K604F371-V396 HydrophobicContact CD2-CG2 4.34Å; F371-V396 HydrophobicContact CE1-CG2 4.27Å; F371-V396 HydrophobicContact CE2-CG2 3.66Å; F371-V396 HydrophobicContact CZ-CG2 3.62Å; F371-V396 CarbonylContact O-C 3.58Å; F371-V396 WeakPolarHBondContact O-CA 3.48Å; L373-V396 HydrophobicContact CB-CG1 3.58Å; L373-V396 HydrophobicContact CD2-CG1 4.42Å; F390-V396 HydrophobicContact CB-CG1 4.48Å; F390-V396 HydrophobicContact CD2-CB 4.08Å; F390-V396 HydrophobicContact CD2-CG1 3.62Å; F390-V396 HydrophobicContact CE2-CG1 4.41Å; C393-V396 HydrophobicContact CB-CG2 3.74Å; P394-V396 VanDerWaalsContact C-N 3.28Å; P394-V396 PolarHBondContact O-N 2.64Å; V396-G398 VanDerWaalsContact C-N 3.34Å; V396-G398 WeakPolarHBondContact CG1-O 3.38Å; V396-G398 PolarHBondContact O-N 3.06Å; V396-K604 WeakPolarHBondContact O-CD 3.47Å
397R95.9Very high95.9Very high24 Ų2414.2 Ų14.29%0.0918%0.084CC..EExtended strand (participates in β ladder)trans-70.2-30-177.3-59.7-51.2-37177.511.1113.5T156 C158 D370 F371 I372 H395 K604 Q605T156-R397 HydrophobicContact CG2-CB 4.29Å; C158-R397 HydrophobicContact CB-CG 4.35Å; D370-R397 HydrophobicContact CB-CG 3.71Å; D370-R397 VanDerWaalsContact CG-CD 3.48Å; D370-R397 WeakPolarHBondContact OD2-CD 3.48Å; D370-R397 IonicContact OD2-NH1 3.88Å; F371-R397 PolarHBondContact O-N 3.39Å; I372-R397 HydrophobicContact CD1-CB 3.99Å; H395-R397 PolarHBondContact O-N 3.05Å; R397-K604 PolarHBondContact NH2-O 3.14Å; R397-K604 PolarHBondContact O-N 3.01Å; R397-Q605 PolarHBondContact NH2-O 3.38Å
398G97.2Very high95.7Very high0 Ų017.2 Ų17.20%010%0.097CC..EExtended strand (participates in β ladder)trans-163163-176.400000112.6L373 V396 A602L373-G398 PolarHBondContact N-O 2.78Å; V396-G398 VanDerWaalsContact C-N 3.34Å; V396-G398 WeakPolarHBondContact CG1-O 3.38Å; V396-G398 PolarHBondContact O-N 3.06Å; G398-A602 CarbonylContact C-O 3.59Å; G398-A602 VanDerWaalsContact CA-O 3.25Å; G398-A602 WeakPolarHBondContact CA-O 3.47Å
399I98.3Very high95.6Very high0 Ų016.6 Ų16.60%010%0.095CC..EExtended strand (participates in β ladder)trans-135.7142.1179-173.8173.8000111.8L373 L386 L387 F390 L600 M601 A602L373-I399 HydrophobicContact CB-CB 4.5Å; L373-I399 HydrophobicContact CB-CG1 4.34Å; L373-I399 HydrophobicContact CD2-CD1 4.22Å; L373-I399 CarbonylContact O-C 3.57Å; L373-I399 VanDerWaalsContact O-CA 3.22Å; L373-I399 WeakPolarHBondContact O-CA 3.42Å; L386-I399 HydrophobicContact CB-CD1 4.01Å; L387-I399 HydrophobicContact CD2-CD1 4.21Å; F390-I399 HydrophobicContact CB-CB 4.37Å; F390-I399 HydrophobicContact CB-CD1 4.02Å; F390-I399 HydrophobicContact CB-CG2 4.49Å; F390-I399 HydrophobicContact CD1-CB 4.29Å; F390-I399 HydrophobicContact CD1-CG2 3.55Å; F390-I399 HydrophobicContact CD2-CB 4.03Å; F390-I399 HydrophobicContact CD2-CG2 4.01Å; F390-I399 HydrophobicContact CE1-CG2 3.6Å; F390-I399 HydrophobicContact CE2-CB 4.37Å; F390-I399 HydrophobicContact CE2-CG2 4.06Å; F390-I399 HydrophobicContact CG-CB 3.97Å; F390-I399 HydrophobicContact CG-CD1 4.4Å; F390-I399 HydrophobicContact CG-CG2 3.75Å; F390-I399 HydrophobicContact CZ-CG2 3.85Å; I399-L600 HydrophobicContact CG2-CD2 4.46Å; I399-M601 WeakPolarHBondContact O-CA 3.4Å; I399-A602 HydrophobicContact CG2-CB 3.86Å; I399-A602 PolarHBondContact N-O 2.8Å; I399-A602 PolarHBondContact O-N 3.37Å; I399-A602 VanDerWaalsContact O-N 3.14Å
400T98.2Very high95.6Very high0 Ų017 Ų170%010%0.097CC..EExtended strand (participates in β ladder)trans-124.1114.8158.249.60000111.2L145 L148 V149 L152 L373 T374 G375 L600 M601L145-T400 HydrophobicContact CD1-CG2 4.45Å; L148-T400 HydrophobicContact CD2-CG2 4.08Å; L148-T400 HydrophobicContact CG-CG2 4.41Å; V149-T400 WeakPolarHBondContact CG2-OG1 3.4Å; L152-T400 HydrophobicContact CD1-CG2 3.81Å; L152-T400 HydrophobicContact CD2-CG2 3.92Å; L373-T400 PolarHBondContact O-N 3.24Å; T374-T400 VanDerWaalsContact CA-O 3.32Å; T374-T400 WeakPolarHBondContact CA-O 3.31Å; T374-T400 WeakPolarHBondContact CB-OG1 3.3Å; T374-T400 PolarHBondContact OG1-O 3.19Å; T374-T400 PolarHBondContact OG1-OG1 2.89Å; T374-T400 VanDerWaalsContact OG1-OG1 3.12Å; G375-T400 PolarHBondContact N-O 3.25Å; G375-T400 VanDerWaalsContact N-O 3.15Å; T400-L600 CarbonylContact C-O 3.59Å; T400-L600 WeakPolarHBondContact CA-O 3.23Å; T400-M601 HydrophobicContact CG2-CG 4.39Å
401S97.7Very high95.5Very high3 Ų317 Ų172%0.02110%0.097CC..EExtended strand (participates in β ladder)trans-118.5123.3-176.7174.10000112L600S401-L600 PolarHBondContact N-O 3.41Å; S401-L600 PolarHBondContact O-N 3.22Å
402V97.1Very high95.3Very high0 Ų018.5 Ų18.50%011%0.11CC..EExtended strand (participates in β ladder)trans-106.594.5175.1-171.10000109.5L145 G375 L376 H377 A378 F589 V599L145-V402 HydrophobicContact CD1-CG2 4.34Å; L145-V402 HydrophobicContact CD2-CG2 3.78Å; G375-V402 PolarHBondContact O-N 2.92Å; L376-V402 HydrophobicContact CD1-CB 4.35Å; L376-V402 HydrophobicContact CD1-CG1 4.38Å; L376-V402 HydrophobicContact CD1-CG2 4.11Å; H377-V402 CarbonylContact C-O 3.58Å; H377-V402 WeakPolarHBondContact CA-O 3.23Å; H377-V402 PolarHBondContact N-O 3.21Å; A378-V402 PolarHBondContact N-O 2.61Å; V402-F589 HydrophobicContact CG1-CE2 3.9Å; V402-F589 HydrophobicContact CG2-CE2 4.42Å; V402-F589 HydrophobicContact CG2-CZ 4.32Å; V402-V599 HydrophobicContact CG2-CB 4.49Å; V402-V599 HydrophobicContact CG2-CG1 4.07Å; V402-V599 HydrophobicContact CG2-CG2 3.86Å
403A94.2Very high95Very high3 Ų320.2 Ų20.23%0.02511%0.111CC..EExtended strand (participates in β ladder)trans-73.9147173.600000111Y406A403-Y406 HydrophobicContact CB-CE1 3.74Å
404C91.8Very high94.8Very high12 Ų1221.8 Ų21.88%0.08112%0.119CC..  trans-148.1-30.7-175.262.80000117.3H377 R596H377-C404 VanDerWaalsContact CA-SG 3.54Å; H377-C404 HydrophobicContact CB-CB 4.45Å; H377-C404 VanDerWaalsContact CB-SG 3.59Å; C404-R596 HydrophobicContact CB-CB 4.42Å; C404-R596 HydrophobicContact CB-CG 3.73Å
405C94.8Very high94.6Very high28 Ų2821.7 Ų21.719%0.18912%0.119CC..  trans-115.271.5-174.5-700000110.8C379 G380 M407 K408C379-C405 HydrophobicContact CB-CB 4.15Å; G380-C405 PolarHBondContact N-O 3.42Å; C405-M407 VanDerWaalsContact C-N 3.28Å; C405-M407 VanDerWaalsContact C-SD 3.59Å; C405-M407 HydrophobicContact CB-CE 4.09Å; C405-M407 HydrophobicContact CB-SD 3.83Å; C405-M407 PolarHBondContact O-N 3.34Å; C405-K408 HydrophobicContact CB-CB 4.22Å; C405-K408 HydrophobicContact CB-CD 4.23Å; C405-K408 HydrophobicContact CB-CG 4.06Å; C405-K408 WeakPolarHBondContact O-CB 3.43Å; C405-K408 PolarHBondContact O-N 3.04Å
406Y95.7Very high94.3Very high2 Ų226.2 Ų26.21%0.00814%0.144CC..G310 helixtrans-65.8-28.5-174-51-71000113.3A403 K408 I409 R459 A462 C463 E565 V568A403-Y406 HydrophobicContact CB-CE1 3.74Å; Y406-K408 PolarHBondContact O-N 3.42Å; Y406-I409 HydrophobicContact CD1-CD1 3.91Å; Y406-I409 WeakPolarHBondContact O-CB 2.86Å; Y406-I409 WeakPolarHBondContact O-CG1 3.41Å; Y406-I409 PolarHBondContact O-N 2.94Å; Y406-I409 VanDerWaalsContact O-N 3.12Å; Y406-R459 WeakPolarHBondContact CB-O 3.22Å; Y406-R459 PolarHBondContact O-NH1 3.47Å; Y406-A462 HydrophobicContact CD2-CB 3.64Å; Y406-A462 HydrophobicContact CE2-CB 4.31Å; Y406-A462 HydrophobicContact CG-CB 4.31Å; Y406-C463 PolarHBondContact N-SG 3.42Å; Y406-C463 VanDerWaalsContact N-SG 3.44Å; Y406-E565 HydrophobicContact CE2-CB 4.27Å; Y406-E565 HydrophobicContact CE2-CG 3.95Å; Y406-E565 WeakPolarHBondContact CE2-OE1 3.37Å; Y406-E565 WeakPolarHBondContact OH-CG 3.14Å; Y406-E565 PolarHBondContact OH-OE1 3.3Å; Y406-V568 HydrophobicContact CD1-CB 4.39Å; Y406-V568 HydrophobicContact CD1-CG1 4.42Å
407M94.6Very high93.9Very high18 Ų1826.4 Ų26.49%0.08915%0.145CC..G310 helixtrans-64.3-19.4173.176.7-60.6-167.300114C405 P417 Y456 R459 E460C405-M407 VanDerWaalsContact C-N 3.28Å; C405-M407 VanDerWaalsContact C-SD 3.59Å; C405-M407 HydrophobicContact CB-CE 4.09Å; C405-M407 HydrophobicContact CB-SD 3.83Å; C405-M407 PolarHBondContact O-N 3.34Å; M407-P417 WeakPolarHBondContact O-CB 3.33Å; M407-Y456 HydrophobicContact CB-CD2 4.16Å; M407-Y456 HydrophobicContact CB-CE2 3.67Å; M407-Y456 HydrophobicContact CG-CE2 4.11Å; M407-R459 PolarHBondContact N-O 3.03Å; M407-R459 PolarHBondContact O-NH1 3.45Å; M407-E460 HydrophobicContact CB-CB 3.89Å
408K94.3Very high93.2Very high64 Ų6428.6 Ų28.628%0.27816%0.163SC..G310 helixtrans-89.92.6174.9-61.8-160.5168.5-167.10114.3C405 Y406 P417 P418C405-K408 HydrophobicContact CB-CB 4.22Å; C405-K408 HydrophobicContact CB-CD 4.23Å; C405-K408 HydrophobicContact CB-CG 4.06Å; C405-K408 WeakPolarHBondContact O-CB 3.43Å; C405-K408 PolarHBondContact O-N 3.04Å; Y406-K408 PolarHBondContact O-N 3.42Å; K408-P417 WeakPolarHBondContact O-CG 3.14Å; K408-P418 WeakPolarHBondContact CE-O 3.33Å; K408-P418 WeakPolarHBondContact CG-O 3.5Å
409I94.5Very high92Very high1 Ų130.8 Ų30.81%0.00519%0.185CC..SBendtrans-77136.7176-63.3175.9000109.5D381 Y406 R459 V568D381-I409 VanDerWaalsContact OD1-CA 3.27Å; D381-I409 WeakPolarHBondContact OD1-CA 3.4Å; Y406-I409 HydrophobicContact CD1-CD1 3.91Å; Y406-I409 WeakPolarHBondContact O-CB 2.86Å; Y406-I409 WeakPolarHBondContact O-CG1 3.41Å; Y406-I409 PolarHBondContact O-N 2.94Å; Y406-I409 VanDerWaalsContact O-N 3.12Å; I409-R459 VanDerWaalsContact O-CZ 3.29Å; I409-R459 PolarHBondContact O-NH1 3.02Å; I409-R459 PolarHBondContact O-NH2 3.44Å; I409-R459 VanDerWaalsContact O-NH2 3.17Å; I409-V568 HydrophobicContact CD1-CG1 3.94Å
410T95Very high90.9Very high9 Ų934.1 Ų34.16%0.05520%0.203CC..  trans-76.3139.317162.90000110D381 P415 P417 L420 F438 G439 Y440D381-T410 PolarHBondContact OD1-N 3.36Å; D381-T410 PolarHBondContact OD1-OG1 3.21Å; D381-T410 WeakPolarHBondContact OD2-CB 3.14Å; D381-T410 WeakPolarHBondContact OD2-CG2 3.4Å; D381-T410 PolarHBondContact OD2-OG1 3.17Å; T410-P415 WeakPolarHBondContact CG2-O 3.38Å; T410-P417 HydrophobicContact CG2-CG 4.01Å; T410-L420 HydrophobicContact CG2-CD1 3.84Å; T410-L420 HydrophobicContact CG2-CD2 4.12Å; T410-F438 WeakPolarHBondContact OG1-CA 3.32Å; T410-G439 PolarHBondContact O-N 3.28Å; T410-G439 VanDerWaalsContact O-N 3.17Å; T410-G439 PolarHBondContact OG1-N 2.81Å; T410-Y440 PolarHBondContact O-N 2.88Å
411T94.9Very high89.4Confident0 Ų038.9 Ų38.90%023%0.227CC..BIsolated β-bridgetrans-139.8165.7173.3670000109.2E413 N414 P415 Y440 R459T411-E413 WeakPolarHBondContact CB-OE2 3.3Å; T411-E413 PolarHBondContact O-N 3.25Å; T411-E413 VanDerWaalsContact O-N 3.14Å; T411-E413 PolarHBondContact OG1-OE2 3.12Å; T411-N414 PolarHBondContact N-O 2.94Å; T411-N414 CarbonylContact O-C 3.55Å; T411-N414 PolarHBondContact O-N 3.45Å; T411-P415 VanDerWaalsContact O-N 3.16Å; T411-Y440 HydrophobicContact CG2-CD1 3.86Å; T411-R459 VanDerWaalsContact CG2-NH2 3.35Å; T411-R459 PolarHBondContact OG1-NH2 2.7Å
412S92.2Very high87.8Confident69 Ų6942.3 Ų42.348%0.48326%0.256SS..THydrogen-bonded Turntrans-56.8-30.1179.722.70000114
413E89.6Confident86.1Confident94 Ų9445.4 Ų45.444%0.43928%0.276SS..THydrogen-bonded Turntrans-88.6-15.1-179.6-37.967.3-136.800112.2T411 Q453T411-E413 WeakPolarHBondContact CB-OE2 3.3Å; T411-E413 PolarHBondContact O-N 3.25Å; T411-E413 VanDerWaalsContact O-N 3.14Å; T411-E413 PolarHBondContact OG1-OE2 3.12Å; E413-Q453 HydrophobicContact CG-CB 4.31Å; E413-Q453 HydrophobicContact CG-CG 4.32Å; E413-Q453 WeakPolarHBondContact OE1-CG 3.34Å
414N89.6Confident84.3Confident33 Ų3350.4 Ų50.418%0.17631%0.308CS..BIsolated β-bridgetrans-148.575.9-177.8-177.613.5000109.9T411 N416T411-N414 PolarHBondContact N-O 2.94Å; T411-N414 CarbonylContact O-C 3.55Å; T411-N414 PolarHBondContact O-N 3.45Å; N414-N416 VanDerWaalsContact C-N 3.29Å; N414-N416 PolarHBondContact O-N 2.77Å
415P89.8Confident82.3Confident60 Ų6058 Ų5839%0.3935%0.347SS..SBendtrans-75.4-16.5-178.230.1-36.6000113.3T410 T411 P417 F438T410-P415 WeakPolarHBondContact CG2-O 3.38Å; T411-P415 VanDerWaalsContact O-N 3.16Å; P415-P417 VanDerWaalsContact C-CD 3.45Å; P415-P417 WeakPolarHBondContact O-CD 3.46Å; P415-F438 HydrophobicContact CB-CE1 3.9Å
416N88.9Confident79.9Confident130 Ų13061 Ų6170%0.69537%0.368SS*.SBendtrans-126.263.9-176.3-65.7-63.5000111.5N414N414-N416 VanDerWaalsContact C-N 3.29Å; N414-N416 PolarHBondContact O-N 2.77Å
417P87Confident77.3Confident4 Ų466.5 Ų66.53%0.02640%0.404CS..  trans-69152.4-178.731.1-37.2000112.2M407 K408 T410 P415 G419 L420M407-P417 WeakPolarHBondContact O-CB 3.33Å; K408-P417 WeakPolarHBondContact O-CG 3.14Å; T410-P417 HydrophobicContact CG2-CG 4.01Å; P415-P417 VanDerWaalsContact C-CD 3.45Å; P415-P417 WeakPolarHBondContact O-CD 3.46Å; P417-G419 PolarHBondContact O-N 3.39Å; P417-L420 HydrophobicContact CG-CB 4.37Å; P417-L420 WeakPolarHBondContact O-CB 3.41Å; P417-L420 PolarHBondContact O-N 3.48Å; P417-L420 VanDerWaalsContact O-N 3.16Å
418P81.4Confident74.6Confident70 Ų7073.1 Ų73.146%0.45544%0.439SS..THydrogen-bonded Turntrans-54.3123179.9-28.535.4000114.3K408 Y456K408-P418 WeakPolarHBondContact CE-O 3.33Å; K408-P418 WeakPolarHBondContact CG-O 3.5Å; P418-Y456 HydrophobicContact CG-CE2 3.99Å
419G71.6Confident72Confident46 Ų4676.2 Ų76.247%0.47447%0.466SS..THydrogen-bonded Turntrans74.52817900000114.5P417P417-G419 PolarHBondContact O-N 3.39Å
420L75.3Confident69.3Low71 Ų7182.1 Ų82.137%0.37250%0.502SS..  trans-60.8136.4155.1-17568000109.6T410 P417T410-L420 HydrophobicContact CG2-CD1 3.84Å; T410-L420 HydrophobicContact CG2-CD2 4.12Å; P417-L420 HydrophobicContact CG-CB 4.37Å; P417-L420 WeakPolarHBondContact O-CB 3.41Å; P417-L420 PolarHBondContact O-N 3.48Å; P417-L420 VanDerWaalsContact O-N 3.16Å
421I67.9Low66.7Low99 Ų9987.9 Ų87.951%0.50854%0.542SS..  trans-85.9113.2172.8-60.3174.7000107.6A188A188-I421 HydrophobicContact CB-CD1 4.34Å
422A63.2Low63.9Low75 Ų7595.8 Ų95.862%0.6258%0.579SS**  trans-66.3141.4173.700000110.6
423P62.4Low61.4Low65 Ų6597.5 Ų97.542%0.42260%0.598SS.*  trans-64.4142.3175.127.7-34.5000110.5W232 L425W232-P423 HydrophobicContact CE3-CB 4.49Å; W232-P423 HydrophobicContact CH2-CB 3.87Å; W232-P423 HydrophobicContact CZ3-CB 3.84Å; P423-L425 PolarHBondContact O-N 2.82Å
424P54.9Low59.3Low109 Ų10996.5 Ų96.571%0.70860%0.602SS**SBendtrans-62.4110.4172-21.533.3000111S426P424-S426 PolarHBondContact O-N 2.94Å
425L50.3Low57.4Low172 Ų172103.7 Ų103.790%0.90163%0.633SS**  trans36.171.8169.5-69.4171.4000115.8P423P423-L425 PolarHBondContact O-N 2.82Å
426S44.9Very low55.9Low89 Ų89104.5 Ų104.562%0.62264%0.641SS**  trans-65.2140.7157.350.70000110.4P424P424-S426 PolarHBondContact O-N 2.94Å
427P41.3Very low55.6Low119 Ų119103 Ų10377%0.77363%0.629SS**  trans-57.3173172.3-26.436000114
428L38.1Very low55.9Low157 Ų157105.2 Ų105.282%0.82264%0.639SS**SBendtrans-42.7142.2-179.8-109.567.6000113T430L428-T430 PolarHBondContact O-N 3.2Å
429P39.6Very low56.5Low128 Ų128102 Ų10283%0.83162%0.618SS**  trans-65.5102.417827.8-34.5000110.7
430T37.6Very low57.7Low125 Ų12599.8 Ų99.877%0.76760%0.595SS**  trans-64.2137.5162.940.20000109.2L428 E432L428-T430 PolarHBondContact O-N 3.2Å; T430-E432 PolarHBondContact O-N 3.04Å
431S39.9Very low58.8Low130 Ų13097.3 Ų97.391%0.90958%0.584SS**SBendtrans-79.347.1-169.8-174.70000113.7
432E36.6Very low60.1Low166 Ų16693.5 Ų93.578%0.77656%0.564SS**  trans-115112168.2-70.1-165.8174.500110.1T430 S434T430-E432 PolarHBondContact O-N 3.04Å; E432-S434 PolarHBondContact O-N 3.35Å
433A39.7Very low61.8Low106 Ų10690 Ų9088%0.87653%0.534SS*.  trans-73.858.5174.400000111.2H435A433-H435 PolarHBondContact O-N 2.86Å
434S44.5Very low63.4Low73 Ų7390.4 Ų90.451%0.5154%0.539SS..  trans-50.1128.816863.50000109E432 S436E432-S434 PolarHBondContact O-N 3.35Å; S434-S436 PolarHBondContact O-N 2.98Å
435H51.1Low65.5Low183 Ų18390 Ų9085%0.84752%0.524SS*.  trans-46.6113.9-171.7-69-91.7000111A433 E437A433-H435 PolarHBondContact O-N 2.86Å; H435-E437 PolarHBondContact O-N 3.12Å
436S58.3Low67.7Low78 Ų7881.8 Ų81.855%0.54548%0.481SS..  trans-63.3104.6-179.4-70.30000109.3S434 F438S434-S436 PolarHBondContact O-N 2.98Å; S436-F438 VanDerWaalsContact CB-CZ 3.46Å; S436-F438 WeakPolarHBondContact O-CD2 3.49Å; S436-F438 WeakPolarHBondContact O-CE2 3.44Å; S436-F438 WeakPolarHBondContact O-CG 3.36Å; S436-F438 PolarHBondContact O-N 3.49Å
437E82.3Confident70.2Confident97 Ų9783.5 Ų83.545%0.45348%0.479SS..  trans-78.774.1-173.5-132.1-149.7133.900110.8R388 H435R388-E437 VanDerWaalsContact CZ-CD 3.43Å; R388-E437 IonicContact CZ-OE1 2.74Å; R388-E437 IonicContact CZ-OE2 3.76Å; R388-E437 IonicContact NE-OE1 3.69Å; R388-E437 PolarHBondContact NE-OE1 3.44Å; R388-E437 IonicContact NE-OE2 2.67Å; R388-E437 PolarHBondContact NE-OE2 3.49Å; R388-E437 PolarHBondContact NH1-O 3.29Å; R388-E437 VanDerWaalsContact NH2-CG 3.33Å; R388-E437 PolarHBondContact NH2-O 3.42Å; R388-E437 VanDerWaalsContact NH2-O 3.07Å; R388-E437 IonicContact NH2-OE1 3.49Å; R388-E437 PolarHBondContact NH2-OE1 3.31Å; R388-E437 IonicContact NH2-OE2 2.68Å; H435-E437 PolarHBondContact O-N 3.12Å
438F92.4Very high72.9Confident52 Ų5281 Ų8123%0.22847%0.474CS..  trans-55158.6-179.5-61.5-58.3000112.6R388 T410 P415 S436 Y440R388-F438 PolarHBondContact NH2-O 3.07Å; T410-F438 WeakPolarHBondContact OG1-CA 3.32Å; P415-F438 HydrophobicContact CB-CE1 3.9Å; S436-F438 VanDerWaalsContact CB-CZ 3.46Å; S436-F438 WeakPolarHBondContact O-CD2 3.49Å; S436-F438 WeakPolarHBondContact O-CE2 3.44Å; S436-F438 WeakPolarHBondContact O-CG 3.36Å; S436-F438 PolarHBondContact O-N 3.49Å; F438-Y440 VanDerWaalsContact C-N 3.28Å
439G94.5Very high75.7Confident1 Ų174.3 Ų74.31%0.0144%0.439CS..SBendtrans-76-14.2176.600000114.2D381 T410D381-G439 WeakPolarHBondContact OD1-CA 3.27Å; T410-G439 PolarHBondContact O-N 3.28Å; T410-G439 VanDerWaalsContact O-N 3.17Å; T410-G439 PolarHBondContact OG1-N 2.81Å
440Y97.1Very high78.5Confident1 Ų173.3 Ų73.30%0.00443%0.433CS..SBendtrans-154.2143.7167.9170.4-88.7000111.4T410 T411 F438 V446 H452 L454 L567 V568 D571T410-Y440 PolarHBondContact O-N 2.88Å; T411-Y440 HydrophobicContact CG2-CD1 3.86Å; F438-Y440 VanDerWaalsContact C-N 3.28Å; Y440-V446 HydrophobicContact CE2-CG1 4.21Å; Y440-H452 VanDerWaalsContact CE1-O 3.28Å; Y440-H452 WeakPolarHBondContact CE1-O 3.32Å; Y440-H452 PolarHBondContact OH-O 2.93Å; Y440-L454 HydrophobicContact CD1-CD1 4.28Å; Y440-L454 HydrophobicContact CE1-CB 4.07Å; Y440-L454 HydrophobicContact CE1-CD1 3.67Å; Y440-L454 HydrophobicContact CE1-CG 3.75Å; Y440-L454 HydrophobicContact CE2-CD1 4.06Å; Y440-L567 WeakPolarHBondContact OH-CD2 3.43Å; Y440-V568 HydrophobicContact CD2-CB 4.43Å; Y440-V568 HydrophobicContact CD2-CG1 3.72Å; Y440-V568 HydrophobicContact CE2-CG1 4.38Å; Y440-V568 HydrophobicContact CG-CG1 4.31Å; Y440-D571 HydrophobicContact CD2-CB 4.19Å; Y440-D571 WeakPolarHBondContact CD2-OD2 3.48Å; Y440-D571 HydrophobicContact CE2-CB 3.96Å
441P97.3Very high81.2Confident19 Ų1968.6 Ų68.612%0.12341%0.409CS..  cis-72.2149.6-11.731.4-34.8000111.7V446 Q447P441-V446 HydrophobicContact CB-CB 4.25Å; P441-V446 HydrophobicContact CB-CG1 4.03Å; P441-Q447 HydrophobicContact CB-CB 4.43Å; P441-Q447 HydrophobicContact CG-CB 3.78Å; P441-Q447 HydrophobicContact CG-CG 4.03Å
442M97Very high83.9Confident19 Ų1963.2 Ų63.29%0.09437%0.37CS..  trans-91.7-35.5172.1-64.5-164.773.200112.4A384 L387 R388 D571 R572 Y575A384-M442 HydrophobicContact CB-CE 3.84Å; A384-M442 HydrophobicContact CB-CG 4.25Å; A384-M442 HydrophobicContact CB-SD 3.53Å; A384-M442 VanDerWaalsContact CB-SD 3.53Å; L387-M442 HydrophobicContact CB-CE 3.95Å; L387-M442 HydrophobicContact CB-SD 4.33Å; L387-M442 HydrophobicContact CD1-SD 3.8Å; R388-M442 HydrophobicContact CG-CE 4.15Å; M442-D571 VanDerWaalsContact N-CG 3.34Å; M442-D571 PolarHBondContact N-OD1 3.22Å; M442-D571 VanDerWaalsContact N-OD1 3.13Å; M442-D571 PolarHBondContact N-OD2 3.28Å; M442-R572 HydrophobicContact SD-CG 4.2Å; M442-Y575 HydrophobicContact CB-CD2 3.94Å; M442-Y575 HydrophobicContact CB-CG 3.89Å; M442-Y575 HydrophobicContact CE-CD1 3.85Å; M442-Y575 HydrophobicContact CE-CD2 4.31Å; M442-Y575 HydrophobicContact CE-CE1 3.67Å; M442-Y575 HydrophobicContact CE-CE2 4.12Å; M442-Y575 HydrophobicContact CE-CG 4.16Å; M442-Y575 VanDerWaalsContact O-CD2 3.27Å; M442-Y575 WeakPolarHBondContact O-CD2 3.47Å
443S97.4Very high86.8Confident0 Ų058.8 Ų58.80%035%0.349CS..SBendtrans-86.3138.4-175.964.10000112.4W445 V446 Q447 D571 E578S443-W445 PolarHBondContact O-N 3.44Å; S443-V446 PolarHBondContact O-N 3.48Å; S443-V446 VanDerWaalsContact OG-CB 3.31Å; S443-V446 WeakPolarHBondContact OG-CB 3.22Å; S443-V446 VanDerWaalsContact OG-CG2 3.26Å; S443-V446 WeakPolarHBondContact OG-CG2 3.26Å; S443-V446 PolarHBondContact OG-N 2.97Å; S443-Q447 WeakPolarHBondContact O-CB 3.47Å; S443-Q447 PolarHBondContact O-N 3.4Å; S443-D571 WeakPolarHBondContact CB-O 3.32Å; S443-D571 WeakPolarHBondContact CB-OD1 3.26Å; S443-D571 PolarHBondContact N-OD1 2.88Å; S443-D571 PolarHBondContact OG-OD1 3.24Å; S443-E578 WeakPolarHBondContact CA-OE2 2.83Å
444S96.9Very high89.5Confident75 Ų7554.1 Ų54.152%0.52431%0.309SS..Hα-helixtrans-60.2-32.8172.969.50000111.9G448 E578S444-G448 PolarHBondContact O-N 3.37Å; S444-E578 WeakPolarHBondContact CA-OE1 3.44Å; S444-E578 PolarHBondContact N-OE1 3.33Å; S444-E578 PolarHBondContact N-OE2 3.44Å; S444-E578 PolarHBondContact OG-OE1 3.06Å; S444-E578 PolarHBondContact OG-OE2 3.15Å
445W97.8Very high92Very high100 Ų10051.9 Ų51.938%0.37929%0.294SS..Hα-helixtrans-63.3-52.1176.5-176.4-96.8000112.5R13 S443 Q447 G448 L449 L574 E578R13-W445 HydrophobicContact CB-CD2 4.18Å; R13-W445 HydrophobicContact CB-CH2 4.44Å; R13-W445 HydrophobicContact CB-CZ2 3.69Å; R13-W445 HydrophobicContact CG-CD2 3.63Å; R13-W445 HydrophobicContact CG-CE3 4.17Å; R13-W445 HydrophobicContact CG-CG 3.9Å; R13-W445 HydrophobicContact CG-CZ2 4.02Å; R13-W445 PolarHBondContact O-NE1 3.24Å; R13-W445 VanDerWaalsContact O-NE1 3.15Å; S443-W445 PolarHBondContact O-N 3.44Å; W445-Q447 VanDerWaalsContact C-N 3.34Å; W445-G448 PolarHBondContact O-N 3.43Å; W445-L449 PolarHBondContact O-N 3.24Å; W445-L574 HydrophobicContact CB-CD1 4.45Å; W445-L574 HydrophobicContact CG-CD1 4.4Å; W445-E578 PolarHBondContact N-OE1 2.85Å
446V98.1Very high94.1Very high0 Ų046.4 Ų46.40%027%0.266CS..Hα-helixtrans-68.1-37.2-179.7176.10000110.7A16 Y440 P441 S443 G448 L449 H452 L567 D571 L574A16-V446 HydrophobicContact CB-CG2 4.18Å; Y440-V446 HydrophobicContact CE2-CG1 4.21Å; P441-V446 HydrophobicContact CB-CB 4.25Å; P441-V446 HydrophobicContact CB-CG1 4.03Å; S443-V446 PolarHBondContact O-N 3.48Å; S443-V446 VanDerWaalsContact OG-CB 3.31Å; S443-V446 WeakPolarHBondContact OG-CB 3.22Å; S443-V446 VanDerWaalsContact OG-CG2 3.26Å; S443-V446 WeakPolarHBondContact OG-CG2 3.26Å; S443-V446 PolarHBondContact OG-N 2.97Å; V446-G448 PolarHBondContact O-N 3.07Å; V446-L449 PolarHBondContact O-N 3.5Å; V446-L449 VanDerWaalsContact O-N 3.08Å; V446-H452 HydrophobicContact CG1-CB 3.91Å; V446-H452 VanDerWaalsContact O-CB 3.27Å; V446-H452 WeakPolarHBondContact O-CB 3.45Å; V446-H452 VanDerWaalsContact O-CG 3.26Å; V446-H452 PolarHBondContact O-ND1 3.05Å; V446-H452 VanDerWaalsContact O-ND1 3.13Å; V446-L567 HydrophobicContact CG1-CD1 4.26Å; V446-L567 HydrophobicContact CG2-CD1 4.49Å; V446-D571 HydrophobicContact CB-CB 4.42Å; V446-D571 HydrophobicContact CG2-CB 4.06Å; V446-L574 HydrophobicContact CG2-CD1 3.82Å
447Q96.9Very high95.8Very high125 Ų12543.7 Ų43.758%0.58425%0.245SC*.Hα-helixtrans-59.3-33.7172.6-166.4179.626.900112.8P441 S443 W445 H452P441-Q447 HydrophobicContact CB-CB 4.43Å; P441-Q447 HydrophobicContact CG-CB 3.78Å; P441-Q447 HydrophobicContact CG-CG 4.03Å; S443-Q447 WeakPolarHBondContact O-CB 3.47Å; S443-Q447 PolarHBondContact O-N 3.4Å; W445-Q447 VanDerWaalsContact C-N 3.34Å; Q447-H452 PolarHBondContact O-CE1 2.8Å; Q447-H452 PolarHBondContact O-ND1 3.2Å
448G97.2Very high96.5Very high65 Ų6539.3 Ų39.367%0.6723%0.225SC*.Hα-helixtrans-76.8-13.1175.400000115.3S444 W445 V446S444-G448 PolarHBondContact O-N 3.37Å; W445-G448 PolarHBondContact O-N 3.43Å; V446-G448 PolarHBondContact O-N 3.07Å
449L98.2Very high96.8Very high17 Ų1736.8 Ų36.89%0.08921%0.214CC..SBendtrans-79.6137.2-179-71174.9000111.9A16 R17 T20 W445 V446 H452A16-L449 HydrophobicContact CB-CD1 3.77Å; R17-L449 HydrophobicContact CB-CD2 4.22Å; R17-L449 HydrophobicContact CG-CD2 4.34Å; T20-L449 HydrophobicContact CG2-CB 4.09Å; T20-L449 HydrophobicContact CG2-CD1 3.86Å; W445-L449 PolarHBondContact O-N 3.24Å; V446-L449 PolarHBondContact O-N 3.5Å; V446-L449 VanDerWaalsContact O-N 3.08Å; L449-H452 PolarHBondContact O-ND1 2.81Å
450P97Very high96.8Very high107 Ų10738.7 Ų38.770%0.69522%0.222SC*.THydrogen-bonded Turntrans-64.5140.8169.728.6-34.2000110.1T20 H452T20-P450 PolarHBondContact OG1-O 3.24Å; P450-H452 VanDerWaalsContact C-N 3.31Å; P450-H452 PolarHBondContact O-N 3.4Å
451G95Very high96.7Very high27 Ų2739.3 Ų39.328%0.27823%0.229SC..THydrogen-bonded Turntrans70.519.8176.400000115.4S24 Q453S24-G451 WeakPolarHBondContact OG-CA 3.46Å; S24-G451 PolarHBondContact OG-O 2.99Å; G451-Q453 PolarHBondContact O-N 3.06Å
452H97.1Very high96.6Very high17 Ų1738.4 Ų38.48%0.07922%0.223CC..  trans-70.2-12.8176.271.1-109.4000114.1T20 Y440 V446 Q447 L449 P450 L454T20-H452 HydrophobicContact CG2-CB 3.93Å; Y440-H452 VanDerWaalsContact CE1-O 3.28Å; Y440-H452 WeakPolarHBondContact CE1-O 3.32Å; Y440-H452 PolarHBondContact OH-O 2.93Å; V446-H452 HydrophobicContact CG1-CB 3.91Å; V446-H452 VanDerWaalsContact O-CB 3.27Å; V446-H452 WeakPolarHBondContact O-CB 3.45Å; V446-H452 VanDerWaalsContact O-CG 3.26Å; V446-H452 PolarHBondContact O-ND1 3.05Å; V446-H452 VanDerWaalsContact O-ND1 3.13Å; Q447-H452 PolarHBondContact O-CE1 2.8Å; Q447-H452 PolarHBondContact O-ND1 3.2Å; L449-H452 PolarHBondContact O-ND1 2.81Å; P450-H452 VanDerWaalsContact C-N 3.31Å; P450-H452 PolarHBondContact O-N 3.4Å; H452-L454 PolarHBondContact O-N 2.8Å
453Q96.7Very high96.5Very high72 Ų7238.9 Ų38.934%0.33623%0.228SC..  trans-68.1122.7-172.6-61.175.338.900111.2E413 G451E413-Q453 HydrophobicContact CG-CB 4.31Å; E413-Q453 HydrophobicContact CG-CG 4.32Å; E413-Q453 WeakPolarHBondContact OE1-CG 3.34Å; G451-Q453 PolarHBondContact O-N 3.06Å
454L96.7Very high96.1Very high8 Ų841.8 Ų41.84%0.04224%0.241CC..  trans-105.4111.3-179.2-68.1177.5000110.6L23 Y440 H452 R459 V564 L567 V568L23-L454 HydrophobicContact CD1-CD2 4.09Å; Y440-L454 HydrophobicContact CD1-CD1 4.28Å; Y440-L454 HydrophobicContact CE1-CB 4.07Å; Y440-L454 HydrophobicContact CE1-CD1 3.67Å; Y440-L454 HydrophobicContact CE1-CG 3.75Å; Y440-L454 HydrophobicContact CE2-CD1 4.06Å; H452-L454 PolarHBondContact O-N 2.8Å; L454-R459 HydrophobicContact CB-CG 3.66Å; L454-R459 HydrophobicContact CD1-CG 4.41Å; L454-R459 PolarHBondContact O-NE 2.86Å; L454-V564 HydrophobicContact CD1-CG1 3.96Å; L454-V564 HydrophobicContact CD2-CG1 4.03Å; L454-L567 HydrophobicContact CD1-CD2 4.37Å; L454-L567 HydrophobicContact CD2-CD2 4.25Å; L454-L567 HydrophobicContact CG-CD2 4.49Å; L454-V568 HydrophobicContact CD1-CG2 3.58Å
455S96.3Very high95.5Very high27 Ų2739 Ų3919%0.18922%0.223CC..  trans-58.2158.5177.676.50000112D31 K457 A458 R459D31-S455 VanDerWaalsContact CG-CB 3.48Å; D31-S455 WeakPolarHBondContact OD1-CB 3.29Å; D31-S455 PolarHBondContact OD1-OG 3.25Å; D31-S455 WeakPolarHBondContact OD2-CB 3.48Å; D31-S455 PolarHBondContact OD2-OG 3.39Å; S455-K457 PolarHBondContact O-N 2.82Å; S455-K457 PolarHBondContact OG-N 3.1Å; S455-A458 PolarHBondContact O-N 3.26Å; S455-A458 WeakPolarHBondContact OG-CB 3.21Å; S455-A458 PolarHBondContact OG-N 3.22Å; S455-R459 WeakPolarHBondContact O-CB 3.45Å; S455-R459 WeakPolarHBondContact O-CG 3.45Å; S455-R459 PolarHBondContact O-N 3.25Å
456Y95.5Very high95.2Very high68 Ų6835.3 Ų35.327%0.26721%0.21SC..Hα-helixtrans-52.9-38.8171.2174.9-98000111.8F33 M407 P418 R459 E460F33-Y456 HydrophobicContact CZ-CD1 4.46Å; M407-Y456 HydrophobicContact CB-CD2 4.16Å; M407-Y456 HydrophobicContact CB-CE2 3.67Å; M407-Y456 HydrophobicContact CG-CE2 4.11Å; P418-Y456 HydrophobicContact CG-CE2 3.99Å; Y456-R459 PolarHBondContact O-N 3.2Å; Y456-E460 HydrophobicContact CE1-CB 4.49Å; Y456-E460 WeakPolarHBondContact O-CB 3.22Å; Y456-E460 PolarHBondContact O-N 3.34Å
457K95.3Very high94.8Very high21 Ų2137.3 Ų37.39%0.09122%0.219CC..Hα-helixtrans-74.9-39.1-176.8-175.551.9-178.81680113D31 S32 F33 S455 R459 E460 G461D31-K457 WeakPolarHBondContact O-CG 3.44Å; S32-K457 WeakPolarHBondContact O-CE 3.4Å; S32-K457 WeakPolarHBondContact O-CG 3.08Å; F33-K457 HydrophobicContact CD1-CD 4Å; F33-K457 HydrophobicContact CD1-CG 4.42Å; F33-K457 HydrophobicContact CD2-CB 4.38Å; F33-K457 HydrophobicContact CD2-CG 4.2Å; F33-K457 HydrophobicContact CE1-CB 4.36Å; F33-K457 HydrophobicContact CE1-CD 4.02Å; F33-K457 HydrophobicContact CE1-CG 4.38Å; F33-K457 HydrophobicContact CE2-CB 3.84Å; F33-K457 HydrophobicContact CE2-CG 4.14Å; F33-K457 HydrophobicContact CG-CD 4.33Å; F33-K457 HydrophobicContact CG-CG 4.34Å; F33-K457 HydrophobicContact CZ-CB 3.83Å; F33-K457 HydrophobicContact CZ-CD 4.36Å; F33-K457 HydrophobicContact CZ-CG 4.24Å; S455-K457 PolarHBondContact O-N 2.82Å; S455-K457 PolarHBondContact OG-N 3.1Å; K457-R459 VanDerWaalsContact C-N 3.29Å; K457-R459 PolarHBondContact O-N 3.06Å; K457-E460 IonicContact NZ-OE1 3.18Å; K457-E460 PolarHBondContact NZ-OE1 2.72Å; K457-E460 IonicContact NZ-OE2 2.82Å; K457-E460 PolarHBondContact NZ-OE2 2.8Å; K457-E460 PolarHBondContact O-N 3.21Å; K457-G461 PolarHBondContact O-N 3.24Å
458A97.2Very high94.3Very high4 Ų434.2 Ų34.23%0.03321%0.207CC..Hα-helixtrans-60.4-41.517100000111.2S30 S455 G461 A462 V564S30-A458 PolarHBondContact O-N 2.73Å; S455-A458 PolarHBondContact O-N 3.26Å; S455-A458 WeakPolarHBondContact OG-CB 3.21Å; S455-A458 PolarHBondContact OG-N 3.22Å; A458-G461 PolarHBondContact O-N 3.12Å; A458-A462 PolarHBondContact O-N 3.33Å; A458-A462 VanDerWaalsContact O-N 3.07Å; A458-V564 HydrophobicContact CB-CG2 4.17Å
459R97.1Very high94.2Very high0 Ų031.2 Ų31.20%018%0.176CC..Hα-helixtrans-73.6-25.6178.4-65.2-170.1-74.7119.9-23.6113.8Y406 M407 I409 T411 L454 S455 Y456 K457Y406-R459 WeakPolarHBondContact CB-O 3.22Å; Y406-R459 PolarHBondContact O-NH1 3.47Å; M407-R459 PolarHBondContact N-O 3.03Å; M407-R459 PolarHBondContact O-NH1 3.45Å; I409-R459 VanDerWaalsContact O-CZ 3.29Å; I409-R459 PolarHBondContact O-NH1 3.02Å; I409-R459 PolarHBondContact O-NH2 3.44Å; I409-R459 VanDerWaalsContact O-NH2 3.17Å; T411-R459 VanDerWaalsContact CG2-NH2 3.35Å; T411-R459 PolarHBondContact OG1-NH2 2.7Å; L454-R459 HydrophobicContact CB-CG 3.66Å; L454-R459 HydrophobicContact CD1-CG 4.41Å; L454-R459 PolarHBondContact O-NE 2.86Å; S455-R459 WeakPolarHBondContact O-CB 3.45Å; S455-R459 WeakPolarHBondContact O-CG 3.45Å; S455-R459 PolarHBondContact O-N 3.25Å; Y456-R459 PolarHBondContact O-N 3.2Å; K457-R459 VanDerWaalsContact C-N 3.29Å; K457-R459 PolarHBondContact O-N 3.06Å
460E95.6Very high93.9Very high41 Ų4131.5 Ų31.519%0.19218%0.177CC..Hα-helixtrans-74.7-39.1166.7176.9-101.6-118.400111.3M407 Y456 K457 A462 C463 H464M407-E460 HydrophobicContact CB-CB 3.89Å; Y456-E460 HydrophobicContact CE1-CB 4.49Å; Y456-E460 WeakPolarHBondContact O-CB 3.22Å; Y456-E460 PolarHBondContact O-N 3.34Å; K457-E460 IonicContact NZ-OE1 3.18Å; K457-E460 PolarHBondContact NZ-OE1 2.72Å; K457-E460 IonicContact NZ-OE2 2.82Å; K457-E460 PolarHBondContact NZ-OE2 2.8Å; K457-E460 PolarHBondContact O-N 3.21Å; E460-A462 VanDerWaalsContact C-N 3.28Å; E460-A462 PolarHBondContact O-N 3.43Å; E460-C463 WeakPolarHBondContact O-CA 3.47Å; E460-C463 VanDerWaalsContact O-CB 3.26Å; E460-C463 WeakPolarHBondContact O-CB 3.43Å; E460-C463 PolarHBondContact O-N 2.94Å; E460-H464 IonicContact OE2-CE1 3.42Å; E460-H464 PolarHBondContact OE2-CE1 3.45Å; E460-H464 IonicContact OE2-ND1 3.58Å
461G95.1Very high93.6Very high14 Ų1429.5 Ų29.514%0.14416%0.158CC..Hα-helixtrans-55.4-44.2174.600000111.9K457 A458 C463 H464 A561K457-G461 PolarHBondContact O-N 3.24Å; A458-G461 PolarHBondContact O-N 3.12Å; G461-C463 PolarHBondContact O-N 3.05Å; G461-H464 WeakPolarHBondContact O-CB 3.45Å; G461-H464 PolarHBondContact O-N 2.9Å; G461-A561 WeakPolarHBondContact O-CB 3.38Å
462A95.6Very high93.6Very high0 Ų030.8 Ų30.80%015%0.154CC..THydrogen-bonded Turntrans-57.1-16.9173.600000114.9Y406 A458 E460 V564 E565 R596Y406-A462 HydrophobicContact CD2-CB 3.64Å; Y406-A462 HydrophobicContact CE2-CB 4.31Å; Y406-A462 HydrophobicContact CG-CB 4.31Å; A458-A462 PolarHBondContact O-N 3.33Å; A458-A462 VanDerWaalsContact O-N 3.07Å; E460-A462 VanDerWaalsContact C-N 3.28Å; E460-A462 PolarHBondContact O-N 3.43Å; A462-V564 HydrophobicContact CB-CB 4.04Å; A462-V564 HydrophobicContact CB-CG1 3.9Å; A462-E565 HydrophobicContact CB-CB 4.36Å; A462-R596 PolarHBondContact O-NH2 2.94Å
463C93.1Very high93.5Very high28 Ų2830 Ų3019%0.18915%0.151CC..THydrogen-bonded Turntrans-90.1-3.5175.1-60.60000113.6Y406 E460 G461 R596Y406-C463 PolarHBondContact N-SG 3.42Å; Y406-C463 VanDerWaalsContact N-SG 3.44Å; E460-C463 WeakPolarHBondContact O-CA 3.47Å; E460-C463 VanDerWaalsContact O-CB 3.26Å; E460-C463 WeakPolarHBondContact O-CB 3.43Å; E460-C463 PolarHBondContact O-N 2.94Å; G461-C463 PolarHBondContact O-N 3.05Å; C463-R596 VanDerWaalsContact C-NH1 3.28Å; C463-R596 PolarHBondContact O-NH1 2.84Å
464H89.7Confident93.4Very high62 Ų6231.6 Ų31.629%0.28715%0.154SC..SBendtrans-85.5166.9172.5-63.4135.7000112.5E460 G461 L558 R596E460-H464 IonicContact OE2-CE1 3.42Å; E460-H464 PolarHBondContact OE2-CE1 3.45Å; E460-H464 IonicContact OE2-ND1 3.58Å; G461-H464 WeakPolarHBondContact O-CB 3.45Å; G461-H464 PolarHBondContact O-N 2.9Å; H464-L558 HydrophobicContact CB-CD1 3.4Å; H464-R596 PolarHBondContact O-NH1 3.17Å; H464-R596 PolarHBondContact O-NH2 3.17Å
465A85.3Confident93.3Very high16 Ų1637 Ų3713%0.13218%0.179CC..  trans-122.8132.2-177.500000110.1P595A465-P595 HydrophobicContact CB-CB 3.53Å; A465-P595 HydrophobicContact CB-CG 3.47Å; A465-P595 VanDerWaalsContact CB-CG 3.47Å
466I91.2Very high93.3Very high23 Ų2341.4 Ų41.412%0.11820%0.196CC..SBendtrans-75.3-37.7174.9-72.4172000109.3L67 Y469 M470 L558 P562L67-I466 HydrophobicContact CB-CG2 4.39Å; I466-Y469 PolarHBondContact O-N 2.9Å; I466-M470 HydrophobicContact CG2-CG 3.88Å; I466-M470 HydrophobicContact CG2-SD 3.47Å; I466-M470 WeakPolarHBondContact CG2-SD 3.39Å; I466-M470 WeakPolarHBondContact O-CG 3.47Å; I466-M470 PolarHBondContact O-N 2.96Å; I466-L558 HydrophobicContact CG1-CD2 4.28Å; I466-L558 HydrophobicContact CG1-CG 3.86Å; I466-P562 HydrophobicContact CD1-CG 3.49Å; I466-P562 VanDerWaalsContact CD1-CG 3.49Å; I466-P562 HydrophobicContact CG1-CG 4.45Å
467E89.3Confident93.2Very high41 Ų4139.4 Ų39.419%0.19219%0.192CC..Hα-helixtrans-61.1-55.1-169.4-58.984.6168.100111.5R98 Y469 H471 P591 A592R98-E467 IonicContact CZ-OE1 3.26Å; R98-E467 VanDerWaalsContact CZ-OE1 3.27Å; R98-E467 IonicContact NE-OE1 3.87Å; R98-E467 PolarHBondContact NE-OE1 2.98Å; R98-E467 IonicContact NH2-OE1 2.65Å; R98-E467 PolarHBondContact NH2-OE1 3.25Å; R98-E467 IonicContact NH2-OE2 3.76Å; E467-Y469 PolarHBondContact O-N 3.19Å; E467-H471 PolarHBondContact O-N 2.69Å; E467-P591 HydrophobicContact CG-CB 4.32Å; E467-A592 HydrophobicContact CB-CB 4.4Å
468D87.4Confident93.1Very high61 Ų6139.8 Ų39.833%0.32620%0.202SC..Hα-helixtrans-63.7-22173.7-74-38.5000113.7R472D468-R472 PolarHBondContact O-NE 3.06Å
469Y93.4Very high92.9Very high2 Ų241.4 Ų41.41%0.00821%0.21CC..Hα-helixtrans-88-39.9-177.2-169.4-107000111.6L67 I466 E467 H471 R472 L473 L480 F554 S555 L558L67-Y469 HydrophobicContact CD1-CD1 3.88Å; L67-Y469 HydrophobicContact CD1-CE1 4.35Å; I466-Y469 PolarHBondContact O-N 2.9Å; E467-Y469 PolarHBondContact O-N 3.19Å; Y469-H471 VanDerWaalsContact C-N 3.25Å; Y469-H471 PolarHBondContact O-N 3.26Å; Y469-R472 PolarHBondContact O-N 3.14Å; Y469-L473 HydrophobicContact CD1-CD1 3.71Å; Y469-L473 HydrophobicContact CD1-CG 4.06Å; Y469-L473 HydrophobicContact CE1-CD1 3.59Å; Y469-L473 HydrophobicContact CE1-CD2 4.07Å; Y469-L473 HydrophobicContact CE1-CG 3.8Å; Y469-L473 WeakPolarHBondContact O-CG 3.48Å; Y469-L473 PolarHBondContact O-N 2.88Å; Y469-L480 HydrophobicContact CE2-CD2 3.67Å; Y469-F554 AromaticContact CD2-CE1 3.94Å; Y469-F554 HydrophobicContact CD2-CE1 3.94Å; Y469-F554 HydrophobicContact CE1-CD1 4.15Å; Y469-F554 HydrophobicContact CE1-CE1 4.35Å; Y469-F554 AromaticContact CE2-CD1 3.79Å; Y469-F554 HydrophobicContact CE2-CD1 3.79Å; Y469-F554 AromaticContact CE2-CE1 3.62Å; Y469-F554 HydrophobicContact CE2-CE1 3.62Å; Y469-F554 HydrophobicContact CG-CE1 4.45Å; Y469-F554 AromaticContact CZ-CD1 3.58Å; Y469-F554 AromaticContact CZ-CE1 3.85Å; Y469-S555 WeakPolarHBondContact CE1-OG 3.46Å; Y469-L558 HydrophobicContact CD1-CD2 3.41Å; Y469-L558 VanDerWaalsContact CD1-CD2 3.41Å; Y469-L558 HydrophobicContact CE1-CD2 4.22Å; Y469-L558 HydrophobicContact CG-CD2 3.62Å
470M93.1Very high92.8Very high23 Ų2341.7 Ų41.711%0.11321%0.211CC..Hα-helixtrans-58.2-35.8171.3-76.117753.700112.5A63 L67 D68 I466 R474A63-M470 HydrophobicContact CB-CB 4.49Å; A63-M470 HydrophobicContact CB-CG 4.48Å; L67-M470 HydrophobicContact CB-CG 3.77Å; L67-M470 HydrophobicContact CB-SD 3.88Å; L67-M470 HydrophobicContact CD1-CG 3.95Å; D68-M470 HydrophobicContact CB-CE 3.47Å; D68-M470 VanDerWaalsContact CB-CE 3.47Å; D68-M470 WeakPolarHBondContact OD2-CE 3.42Å; I466-M470 HydrophobicContact CG2-CG 3.88Å; I466-M470 HydrophobicContact CG2-SD 3.47Å; I466-M470 WeakPolarHBondContact CG2-SD 3.39Å; I466-M470 WeakPolarHBondContact O-CG 3.47Å; I466-M470 PolarHBondContact O-N 2.96Å; M470-R474 WeakPolarHBondContact O-CG 3.38Å; M470-R474 PolarHBondContact O-N 2.93Å
471H90.6Very high92.7Very high64 Ų6443.6 Ų43.630%0.29622%0.217SC..Hα-helixtrans-64.3-50.6173.4-159.6-90000111.6L111 E467 Y469 L473 R474 E475L111-H471 HydrophobicContact CD2-CB 4.3Å; E467-H471 PolarHBondContact O-N 2.69Å; Y469-H471 VanDerWaalsContact C-N 3.25Å; Y469-H471 PolarHBondContact O-N 3.26Å; H471-L473 VanDerWaalsContact C-N 3.25Å; H471-L473 PolarHBondContact O-N 3.5Å; H471-R474 PolarHBondContact O-N 3.21Å; H471-R474 VanDerWaalsContact O-N 3.08Å; H471-E475 IonicContact CE1-OE1 2.67Å; H471-E475 PolarHBondContact CE1-OE1 2.99Å; H471-E475 VanDerWaalsContact CE1-OE1 3.23Å; H471-E475 IonicContact CE1-OE2 3.27Å; H471-E475 PolarHBondContact CE1-OE2 2.86Å; H471-E475 VanDerWaalsContact CE1-OE2 3.25Å; H471-E475 IonicContact ND1-OE1 3.5Å; H471-E475 IonicContact ND1-OE2 3.77Å; H471-E475 PolarHBondContact ND1-OE2 2.93Å; H471-E475 PolarHBondContact O-N 2.87Å
472R93.8Very high92.7Very high55 Ų5543.5 Ų43.521%0.20821%0.213CC..Hα-helixtrans-60.5-32.7177.9-76.3177.7-74173.3-2.4113.2D468 Y469 E476 S477 L480D468-R472 PolarHBondContact O-NE 3.06Å; Y469-R472 PolarHBondContact O-N 3.14Å; R472-E476 PolarHBondContact O-N 3.08Å; R472-S477 VanDerWaalsContact O-CB 3.25Å; R472-S477 WeakPolarHBondContact O-CB 3.45Å; R472-S477 PolarHBondContact O-N 3.33Å; R472-L480 HydrophobicContact CB-CD2 4.41Å
473L96.1Very high92.6Very high0 Ų045.2 Ų45.20%022%0.22CC..Hα-helixtrans-67.1-45.8171.9-78174.8000112.3P59 I62 A63 L67 Y469 H471 E476 L480 V551P59-L473 CarbonylContact C-O 3.58Å; P59-L473 HydrophobicContact CB-CD2 3.9Å; P59-L473 VanDerWaalsContact CB-O 3.26Å; P59-L473 WeakPolarHBondContact CB-O 3.5Å; P59-L473 WeakPolarHBondContact O-CB 3.35Å; I62-L473 HydrophobicContact CB-CD1 4.28Å; I62-L473 HydrophobicContact CB-CD2 4.33Å; I62-L473 HydrophobicContact CG2-CD1 3.96Å; I62-L473 HydrophobicContact CG2-CD2 4.41Å; A63-L473 HydrophobicContact CB-CB 3.86Å; A63-L473 HydrophobicContact CB-CD1 4.11Å; L67-L473 HydrophobicContact CD1-CD1 3.6Å; Y469-L473 HydrophobicContact CD1-CD1 3.71Å; Y469-L473 HydrophobicContact CD1-CG 4.06Å; Y469-L473 HydrophobicContact CE1-CD1 3.59Å; Y469-L473 HydrophobicContact CE1-CD2 4.07Å; Y469-L473 HydrophobicContact CE1-CG 3.8Å; Y469-L473 WeakPolarHBondContact O-CG 3.48Å; Y469-L473 PolarHBondContact O-N 2.88Å; H471-L473 VanDerWaalsContact C-N 3.25Å; H471-L473 PolarHBondContact O-N 3.5Å; L473-E476 PolarHBondContact O-N 3.08Å; L473-L480 HydrophobicContact CD2-CD1 4.17Å; L473-L480 HydrophobicContact CD2-CD2 3.78Å; L473-L480 HydrophobicContact CG-CD2 4.22Å; L473-V551 HydrophobicContact CD2-CG1 3.59Å
474R94.8Very high92.8Very high106 Ų10643.9 Ų43.940%0.421%0.211SC..Hα-helixtrans-69.8-32179.4-73.3173.4175.7150.60.6113.8A63 D64 D68 M470 H471 E476A63-R474 HydrophobicContact CB-CG 3.8Å; D64-R474 IonicContact OD1-CZ 2.85Å; D64-R474 IonicContact OD1-NE 4Å; D64-R474 PolarHBondContact OD1-NE 3.36Å; D64-R474 IonicContact OD1-NH2 3.99Å; D64-R474 PolarHBondContact OD1-NH2 2.78Å; D68-R474 IonicContact OD2-CZ 3.17Å; D68-R474 IonicContact OD2-NH1 2.7Å; D68-R474 IonicContact OD2-NH2 3.97Å; D68-R474 PolarHBondContact OD2-NH2 3.38Å; M470-R474 WeakPolarHBondContact O-CG 3.38Å; M470-R474 PolarHBondContact O-N 2.93Å; H471-R474 PolarHBondContact O-N 3.21Å; H471-R474 VanDerWaalsContact O-N 3.08Å; R474-E476 PolarHBondContact O-N 2.93Å
475E95.1Very high93.2Very high121 Ų12142 Ų4257%0.56520%0.202SC*.THydrogen-bonded Turntrans-80.6-0172.9-68.5-177125.100113.7H471 S477H471-E475 IonicContact CE1-OE1 2.67Å; H471-E475 PolarHBondContact CE1-OE1 2.99Å; H471-E475 VanDerWaalsContact CE1-OE1 3.23Å; H471-E475 IonicContact CE1-OE2 3.27Å; H471-E475 PolarHBondContact CE1-OE2 2.86Å; H471-E475 VanDerWaalsContact CE1-OE2 3.25Å; H471-E475 IonicContact ND1-OE1 3.5Å; H471-E475 IonicContact ND1-OE2 3.77Å; H471-E475 PolarHBondContact ND1-OE2 2.93Å; H471-E475 PolarHBondContact O-N 2.87Å; E475-S477 PolarHBondContact O-N 3.2Å; E475-S477 VanDerWaalsContact O-N 3.12Å
476E94.4Very high93.7Very high120 Ų12041.8 Ų41.856%0.56120%0.198SC*.THydrogen-bonded Turntrans4938.2-172.2-54.5-161.994.800112.4P59 P60 R472 L473 R474 G478P59-E476 HydrophobicContact CB-CG 4.39Å; P60-E476 HydrophobicContact CG-CG 3.82Å; R472-E476 PolarHBondContact O-N 3.08Å; L473-E476 PolarHBondContact O-N 3.08Å; R474-E476 PolarHBondContact O-N 2.93Å; E476-G478 PolarHBondContact O-N 3.23Å
477S94.8Very high94Very high26 Ų2640.7 Ų40.718%0.18219%0.192CC..  trans-59.5130.6-166.2-174.80000111.7R472 E475 L479 L480R472-S477 VanDerWaalsContact O-CB 3.25Å; R472-S477 WeakPolarHBondContact O-CB 3.45Å; R472-S477 PolarHBondContact O-N 3.33Å; E475-S477 PolarHBondContact O-N 3.2Å; E475-S477 VanDerWaalsContact O-N 3.12Å; S477-L479 PolarHBondContact O-N 3.01Å; S477-L480 WeakPolarHBondContact O-CB 3.44Å; S477-L480 WeakPolarHBondContact O-CG 3.5Å; S477-L480 PolarHBondContact O-N 2.68Å
478G92.8Very high94.4Very high28 Ų2838.8 Ų38.829%0.28918%0.183SC..G310 helixtrans-55.9-14.1175.500000114.5E476 L480 R481 H512E476-G478 PolarHBondContact O-N 3.23Å; G478-L480 PolarHBondContact O-N 2.86Å; G478-R481 WeakPolarHBondContact O-CG 3.42Å; G478-H512 WeakPolarHBondContact O-CB 3.38Å
479L93.4Very high94.9Very high38 Ų3835.9 Ų35.920%0.19917%0.168CC..G310 helixtrans-64.3-21.2170.2-71.8169.5000114.1S477 R481 M482 H512S477-L479 PolarHBondContact O-N 3.01Å; L479-R481 VanDerWaalsContact C-N 3.31Å; L479-R481 PolarHBondContact O-N 3.29Å; L479-M482 VanDerWaalsContact O-CB 3.3Å; L479-M482 WeakPolarHBondContact O-CB 3.34Å; L479-M482 VanDerWaalsContact O-CG 3.29Å; L479-M482 WeakPolarHBondContact O-CG 3.48Å; L479-M482 PolarHBondContact O-N 3.38Å; L479-H512 HydrophobicContact CD2-CB 4.42Å; L479-H512 VanDerWaalsContact CD2-ND1 3.31Å; L479-H512 WeakPolarHBondContact CD2-ND1 3.47Å
480L94.6Very high95.1Very high6 Ų635.8 Ų35.83%0.03117%0.167CC..G310 helixtrans-60.6-38.8-179.2-66.4170.4000112.2P59 Y469 R472 L473 S477 G478 M482 H483 V551P59-L480 HydrophobicContact CB-CD1 3.82Å; P59-L480 HydrophobicContact CG-CD1 4.08Å; Y469-L480 HydrophobicContact CE2-CD2 3.67Å; R472-L480 HydrophobicContact CB-CD2 4.41Å; L473-L480 HydrophobicContact CD2-CD1 4.17Å; L473-L480 HydrophobicContact CD2-CD2 3.78Å; L473-L480 HydrophobicContact CG-CD2 4.22Å; S477-L480 WeakPolarHBondContact O-CB 3.44Å; S477-L480 WeakPolarHBondContact O-CG 3.5Å; S477-L480 PolarHBondContact O-N 2.68Å; G478-L480 PolarHBondContact O-N 2.86Å; L480-M482 PolarHBondContact O-N 3.03Å; L480-H483 PolarHBondContact O-N 3.48Å; L480-V551 HydrophobicContact CB-CG2 4.06Å; L480-V551 HydrophobicContact CD2-CG1 4.46Å
481R93.8Very high95.2Very high82 Ų8234.9 Ų34.931%0.30916%0.163SC..Hα-helixtrans-59.6-17.8177.981.2-171.641.6156.2-7.4114.8G478 L479 H483 C484 Y485 H512 E547G478-R481 WeakPolarHBondContact O-CG 3.42Å; L479-R481 VanDerWaalsContact C-N 3.31Å; L479-R481 PolarHBondContact O-N 3.29Å; R481-H483 PolarHBondContact O-N 3.23Å; R481-C484 PolarHBondContact O-N 2.96Å; R481-Y485 HydrophobicContact CB-CD1 4.18Å; R481-Y485 HydrophobicContact CB-CE1 4.19Å; R481-Y485 HydrophobicContact CG-CD1 4.04Å; R481-Y485 HydrophobicContact CG-CE1 3.95Å; R481-Y485 HydrophobicContact CG-CG 4.43Å; R481-Y485 WeakPolarHBondContact O-CB 3.48Å; R481-Y485 WeakPolarHBondContact O-CD1 3.36Å; R481-Y485 PolarHBondContact O-N 3.14Å; R481-H512 PolarHBondContact NH1-O 3.02Å; R481-E547 WeakPolarHBondContact CA-OE1 3.42Å; R481-E547 HydrophobicContact CB-CG 4.27Å; R481-E547 VanDerWaalsContact CB-OE1 3.25Å; R481-E547 WeakPolarHBondContact CB-OE1 3.29Å; R481-E547 WeakPolarHBondContact CB-OE2 3.22Å; R481-E547 PolarHBondContact N-OE1 3.2Å
482M94.2Very high95.5Very high12 Ų1232.4 Ų32.46%0.05915%0.152CC..Hα-helixtrans-59.9-31.4-176.5-68.9-51.8-44.700113.1L293 L479 L480 R486 A511 H512 Y519L293-M482 HydrophobicContact CD1-CB 4.14Å; L293-M482 HydrophobicContact CD2-CG 4.47Å; L479-M482 VanDerWaalsContact O-CB 3.3Å; L479-M482 WeakPolarHBondContact O-CB 3.34Å; L479-M482 VanDerWaalsContact O-CG 3.29Å; L479-M482 WeakPolarHBondContact O-CG 3.48Å; L479-M482 PolarHBondContact O-N 3.38Å; L480-M482 PolarHBondContact O-N 3.03Å; M482-R486 PolarHBondContact O-N 3.08Å; M482-A511 HydrophobicContact CE-CB 3.5Å; M482-A511 VanDerWaalsContact CE-CB 3.5Å; M482-A511 HydrophobicContact SD-CB 3.58Å; M482-A511 VanDerWaalsContact SD-CB 3.58Å; M482-H512 HydrophobicContact SD-CB 4.2Å; M482-Y519 HydrophobicContact CE-CE2 3.77Å
483H94.1Very high95.6Very high35 Ų3529.8 Ų29.816%0.16214%0.142CC..Hα-helixtrans-69.3-45.2174.4-64.5-77.2000111.5I34 L480 R481 R486 A487 V550 F554I34-H483 HydrophobicContact CG2-CB 3.96Å; L480-H483 PolarHBondContact O-N 3.48Å; R481-H483 PolarHBondContact O-N 3.23Å; H483-R486 PolarHBondContact O-N 3.01Å; H483-A487 WeakPolarHBondContact O-CB 3.33Å; H483-A487 PolarHBondContact O-N 3.21Å; H483-V550 HydrophobicContact CB-CG1 3.83Å; H483-F554 AromaticContact CD2-CD1 3.91Å; H483-F554 AromaticContact CE1-CD1 3.68Å; H483-F554 AromaticContact CE1-CE1 3.47Å; H483-F554 VanDerWaalsContact CE1-CE1 3.47Å; H483-F554 WeakPolarHBondContact CE1-CE1 3.2Å; H483-F554 AromaticContact CE1-CZ 3.79Å; H483-F554 AromaticContact NE2-CD1 3.54Å; H483-F554 AromaticContact NE2-CE1 3.36Å; H483-F554 WeakPolarHBondContact NE2-CE1 3.23Å
484C97.4Very high95.6Very high0 Ų032.3 Ų32.30%015%0.152CC..Hα-helixtrans-63.2-42.1174.7-169.80000111.4R481 A487 T488 E547 V550R481-C484 PolarHBondContact O-N 2.96Å; C484-A487 PolarHBondContact O-N 3.05Å; C484-T488 WeakPolarHBondContact O-CB 3.46Å; C484-T488 PolarHBondContact O-N 2.82Å; C484-T488 PolarHBondContact O-OG1 3.15Å; C484-E547 HydrophobicContact CB-CB 4.2Å; C484-E547 HydrophobicContact CB-CG 4.05Å; C484-V550 HydrophobicContact CB-CB 4.35Å; C484-V550 HydrophobicContact CB-CG2 4.09Å
485Y97.1Very high95.5Very high22 Ų2231.8 Ų31.89%0.08615%0.154CC..Hα-helixtrans-62.5-45.5177.1-85.736.4000111.7R481 A487 L489 L514 F516 Y519 L544R481-Y485 HydrophobicContact CB-CD1 4.18Å; R481-Y485 HydrophobicContact CB-CE1 4.19Å; R481-Y485 HydrophobicContact CG-CD1 4.04Å; R481-Y485 HydrophobicContact CG-CE1 3.95Å; R481-Y485 HydrophobicContact CG-CG 4.43Å; R481-Y485 WeakPolarHBondContact O-CB 3.48Å; R481-Y485 WeakPolarHBondContact O-CD1 3.36Å; R481-Y485 PolarHBondContact O-N 3.14Å; Y485-A487 VanDerWaalsContact C-N 3.32Å; Y485-A487 PolarHBondContact O-N 2.96Å; Y485-L489 VanDerWaalsContact O-CB 3.27Å; Y485-L489 WeakPolarHBondContact O-CB 3.46Å; Y485-L489 PolarHBondContact O-N 3.18Å; Y485-L514 WeakPolarHBondContact CE2-O 3.26Å; Y485-L514 PolarHBondContact OH-O 3.31Å; Y485-F516 HydrophobicContact CD1-CD2 4.24Å; Y485-F516 HydrophobicContact CD2-CD2 4.19Å; Y485-F516 HydrophobicContact CE1-CB 4.32Å; Y485-F516 HydrophobicContact CE2-CB 4.21Å; Y485-F516 HydrophobicContact CG-CD2 4.02Å; Y485-F516 PolarHBondContact OH-N 3.39Å; Y485-Y519 AromaticContact CD2-CD1 3.75Å; Y485-Y519 HydrophobicContact CD2-CD1 3.75Å; Y485-Y519 HydrophobicContact CD2-CD2 4.19Å; Y485-Y519 HydrophobicContact CD2-CE1 4.32Å; Y485-Y519 AromaticContact CD2-CG 3.68Å; Y485-Y519 HydrophobicContact CD2-CG 3.68Å; Y485-Y519 HydrophobicContact CE2-CG 4.37Å; Y485-Y519 HydrophobicContact CG-CD1 4.26Å; Y485-L544 HydrophobicContact CD1-CD2 3.79Å; Y485-L544 HydrophobicContact CE1-CD2 3.79Å
486R96.4Very high95.5Very high13 Ų1328.2 Ų28.25%0.04915%0.146CC..Hα-helixtrans-62.9-37.8174.5-81.7-69-73.6118.7-19.3112.1I35 E291 M482 H483 L489 E490 P503 Y519I35-R486 HydrophobicContact CG2-CB 3.72Å; E291-R486 IonicContact OE1-CZ 2.78Å; E291-R486 IonicContact OE1-NE 3.23Å; E291-R486 PolarHBondContact OE1-NE 3.41Å; E291-R486 IonicContact OE1-NH2 3.2Å; E291-R486 PolarHBondContact OE1-NH2 2.75Å; E291-R486 IonicContact OE2-NE 2.68Å; E291-R486 IonicContact OE2-NH2 3.67Å; M482-R486 PolarHBondContact O-N 3.08Å; H483-R486 PolarHBondContact O-N 3.01Å; R486-L489 PolarHBondContact O-N 2.86Å; R486-E490 WeakPolarHBondContact O-CB 3.49Å; R486-E490 PolarHBondContact O-N 3.47Å; R486-P503 PolarHBondContact NH2-O 2.93Å; R486-P503 VanDerWaalsContact NH2-O 3.11Å; R486-Y519 WeakPolarHBondContact CD-OH 3.45Å; R486-Y519 WeakPolarHBondContact CG-OH 3.45Å
487A97.7Very high95.5Very high0 Ų026 Ų260%013%0.134CC..Hα-helixtrans-73.3-40.7-17900000113.8I34 I35 F37 F38 H483 C484 Y485 L489 E490 T491I34-A487 WeakPolarHBondContact O-CB 3.35Å; I35-A487 VanDerWaalsContact O-CA 3.23Å; I35-A487 WeakPolarHBondContact O-CA 3.39Å; F37-A487 HydrophobicContact CB-CB 4.14Å; F38-A487 HydrophobicContact CD2-CB 3.84Å; F38-A487 HydrophobicContact CE2-CB 3.88Å; H483-A487 WeakPolarHBondContact O-CB 3.33Å; H483-A487 PolarHBondContact O-N 3.21Å; C484-A487 PolarHBondContact O-N 3.05Å; Y485-A487 VanDerWaalsContact C-N 3.32Å; Y485-A487 PolarHBondContact O-N 2.96Å; A487-L489 VanDerWaalsContact C-N 3.31Å; A487-E490 PolarHBondContact O-N 3.31Å; A487-T491 WeakPolarHBondContact O-CB 3.26Å; A487-T491 PolarHBondContact O-N 3.26Å; A487-T491 VanDerWaalsContact O-N 3.09Å; A487-T491 PolarHBondContact O-OG1 3.01Å
488T98.1Very high95.4Very high0 Ų029.4 Ų29.40%016%0.155CC..Hα-helixtrans-62.9-40.8171.9-53.10000110.4C484 T491 V492 F516 V540 M543 L544C484-T488 WeakPolarHBondContact O-CB 3.46Å; C484-T488 PolarHBondContact O-N 2.82Å; C484-T488 PolarHBondContact O-OG1 3.15Å; T488-T491 PolarHBondContact O-N 3.29Å; T488-V492 WeakPolarHBondContact O-CG2 3.36Å; T488-V492 PolarHBondContact O-N 3.21Å; T488-V492 VanDerWaalsContact O-N 3.07Å; T488-F516 HydrophobicContact CG2-CD1 4.45Å; T488-F516 HydrophobicContact CG2-CD2 4.4Å; T488-F516 HydrophobicContact CG2-CE1 3.79Å; T488-F516 HydrophobicContact CG2-CE2 3.75Å; T488-F516 HydrophobicContact CG2-CZ 3.4Å; T488-F516 VanDerWaalsContact CG2-CZ 3.4Å; T488-V540 HydrophobicContact CG2-CG1 4.15Å; T488-V540 HydrophobicContact CG2-CG2 4.25Å; T488-M543 HydrophobicContact CG2-CB 4.07Å; T488-M543 HydrophobicContact CG2-CE 3.87Å; T488-M543 HydrophobicContact CG2-SD 4.11Å; T488-L544 HydrophobicContact CG2-CD2 4.47Å
489L97.1Very high95.4Very high0 Ų034.5 Ų34.50%017%0.172CC..Hα-helixtrans-67.9-42.5176.9179.559.8000112.7Y485 R486 A487 T491 V492 I493 V505 F516 Y519 A520 L524Y485-L489 VanDerWaalsContact O-CB 3.27Å; Y485-L489 WeakPolarHBondContact O-CB 3.46Å; Y485-L489 PolarHBondContact O-N 3.18Å; R486-L489 PolarHBondContact O-N 2.86Å; A487-L489 VanDerWaalsContact C-N 3.31Å; L489-T491 PolarHBondContact O-N 2.82Å; L489-V492 PolarHBondContact O-N 3.26Å; L489-I493 HydrophobicContact CD1-CD1 4.05Å; L489-I493 HydrophobicContact CD1-CG1 4.2Å; L489-I493 HydrophobicContact CG-CD1 3.81Å; L489-I493 HydrophobicContact CG-CG1 4.43Å; L489-I493 WeakPolarHBondContact O-CD1 3.09Å; L489-I493 VanDerWaalsContact O-CG1 3.23Å; L489-I493 WeakPolarHBondContact O-CG1 3.47Å; L489-I493 PolarHBondContact O-N 2.93Å; L489-V505 HydrophobicContact CD2-CG1 4.28Å; L489-F516 HydrophobicContact CB-CE2 4.25Å; L489-F516 HydrophobicContact CB-CZ 4.35Å; L489-Y519 HydrophobicContact CB-CE1 4.09Å; L489-Y519 HydrophobicContact CD2-CD1 4.4Å; L489-Y519 HydrophobicContact CD2-CE1 3.66Å; L489-Y519 HydrophobicContact CG-CE1 4.49Å; L489-A520 HydrophobicContact CD1-CB 4.2Å; L489-L524 HydrophobicContact CD1-CD2 3.96Å; L489-L524 HydrophobicContact CD1-CG 4.09Å
490E96.9Very high95.3Very high0 Ų034.6 Ų34.60%017%0.172CC..Hα-helixtrans-55.9-41.6173.2179.967.2-157.400111.6I35 R486 A487 I493 R494 R502 P503I35-E490 HydrophobicContact CB-CB 4.22Å; I35-E490 HydrophobicContact CB-CG 4.33Å; I35-E490 HydrophobicContact CG1-CG 4.24Å; I35-E490 WeakPolarHBondContact O-CB 3.13Å; I35-E490 VanDerWaalsContact O-CG 3.28Å; I35-E490 WeakPolarHBondContact O-CG 3.49Å; R486-E490 WeakPolarHBondContact O-CB 3.49Å; R486-E490 PolarHBondContact O-N 3.47Å; A487-E490 PolarHBondContact O-N 3.31Å; E490-I493 PolarHBondContact O-N 3.39Å; E490-R494 PolarHBondContact O-N 3.22Å; E490-R494 WeakPolarHBondContact OE1-CD 3.4Å; E490-R502 VanDerWaalsContact OE1-CA 3.31Å; E490-R502 WeakPolarHBondContact OE1-CA 3.38Å; E490-R502 PolarHBondContact OE1-N 3.49Å; E490-P503 WeakPolarHBondContact OE2-CD 3.44Å
491T96.9Very high95.1Very high4 Ų439.2 Ų39.23%0.02519%0.189CC..Hα-helixtrans-66.3-46.2179.3-550000111.2A487 T488 L489 I493 R494 E495 M543A487-T491 WeakPolarHBondContact O-CB 3.26Å; A487-T491 PolarHBondContact O-N 3.26Å; A487-T491 VanDerWaalsContact O-N 3.09Å; A487-T491 PolarHBondContact O-OG1 3.01Å; T488-T491 PolarHBondContact O-N 3.29Å; L489-T491 PolarHBondContact O-N 2.82Å; T491-I493 VanDerWaalsContact C-N 3.33Å; T491-I493 PolarHBondContact O-N 3.38Å; T491-R494 PolarHBondContact O-N 3.39Å; T491-E495 VanDerWaalsContact CG2-OE1 3.27Å; T491-E495 WeakPolarHBondContact CG2-OE1 3.46Å; T491-E495 WeakPolarHBondContact O-CG 3.43Å; T491-E495 PolarHBondContact O-N 2.67Å; T491-E495 VanDerWaalsContact O-N 3.09Å; T491-M543 HydrophobicContact CG2-CE 4.05Å; T491-M543 HydrophobicContact CG2-SD 3.82Å
492V96.9Very high94.9Very high12 Ų1240 Ų407%0.07319%0.192CC..Hα-helixtrans-59.4-40.9172.7169.20000112T488 L489 E495 A496 L524 L533 L535 V540T488-V492 WeakPolarHBondContact O-CG2 3.36Å; T488-V492 PolarHBondContact O-N 3.21Å; T488-V492 VanDerWaalsContact O-N 3.07Å; L489-V492 PolarHBondContact O-N 3.26Å; V492-E495 PolarHBondContact O-N 3.47Å; V492-A496 PolarHBondContact O-N 3.16Å; V492-A496 VanDerWaalsContact O-N 3.11Å; V492-L524 HydrophobicContact CG1-CD2 4.3Å; V492-L533 HydrophobicContact CG1-CD2 3.79Å; V492-L535 HydrophobicContact CG1-CD2 3.61Å; V492-L535 HydrophobicContact CG2-CD2 4.2Å; V492-V540 HydrophobicContact CG2-CG2 4.27Å
493I95.8Very high94.7Very high0 Ų040.4 Ų40.40%020%0.196CC..Hα-helixtrans-65.4-48.3178.5-68.8163.2000110.9L489 E490 T491 E495 A496 K497 L500 P503 V505 L524 V527 L529L489-I493 HydrophobicContact CD1-CD1 4.05Å; L489-I493 HydrophobicContact CD1-CG1 4.2Å; L489-I493 HydrophobicContact CG-CD1 3.81Å; L489-I493 HydrophobicContact CG-CG1 4.43Å; L489-I493 WeakPolarHBondContact O-CD1 3.09Å; L489-I493 VanDerWaalsContact O-CG1 3.23Å; L489-I493 WeakPolarHBondContact O-CG1 3.47Å; L489-I493 PolarHBondContact O-N 2.93Å; E490-I493 PolarHBondContact O-N 3.39Å; T491-I493 VanDerWaalsContact C-N 3.33Å; T491-I493 PolarHBondContact O-N 3.38Å; I493-E495 PolarHBondContact O-N 2.63Å; I493-A496 PolarHBondContact O-N 3.41Å; I493-K497 PolarHBondContact O-N 3.13Å; I493-L500 HydrophobicContact CG2-CB 3.77Å; I493-L500 HydrophobicContact CG2-CD1 4.12Å; I493-P503 HydrophobicContact CD1-CG 4.28Å; I493-P503 HydrophobicContact CG2-CG 4.05Å; I493-V505 HydrophobicContact CD1-CG2 4.25Å; I493-L524 HydrophobicContact CG1-CD2 3.87Å; I493-V527 HydrophobicContact CD1-CG1 4.32Å; I493-V527 HydrophobicContact CD1-CG2 3.94Å; I493-V527 HydrophobicContact CG1-CG2 4.07Å; I493-V527 HydrophobicContact CG2-CG2 4.28Å; I493-L529 HydrophobicContact CB-CD1 4.29Å; I493-L529 HydrophobicContact CG1-CD1 4.09Å; I493-L529 HydrophobicContact CG2-CD1 4.04Å
494R95Very high94.2Very high53 Ų5341.6 Ų41.620%0.222%0.218CC..Hα-helixtrans-66.7-19.8179.6-74.9178.862.7179.4-9.3113.3E36 E40 E490 T491 P498 L500E36-R494 IonicContact OE1-NH1 3.77Å; E36-R494 PolarHBondContact OE1-NH1 2.82Å; E40-R494 IonicContact OE1-CZ 3.75Å; E40-R494 IonicContact OE1-NH1 3.28Å; E40-R494 PolarHBondContact OE1-NH1 3.46Å; E40-R494 IonicContact OE1-NH2 3.47Å; E40-R494 PolarHBondContact OE1-NH2 3.43Å; E490-R494 PolarHBondContact O-N 3.22Å; E490-R494 WeakPolarHBondContact OE1-CD 3.4Å; T491-R494 PolarHBondContact O-N 3.39Å; R494-P498 WeakPolarHBondContact O-CA 3.36Å; R494-P498 WeakPolarHBondContact O-CG 3.03Å; R494-L500 WeakPolarHBondContact CG-O 3.48Å
495E93.8Very high93.7Very high95 Ų9542 Ų4244%0.44422%0.22SC..Hα-helixtrans-82.3-40.8172.9-75.5166.6-15700112.7T491 V492 I493 K497 R539T491-E495 VanDerWaalsContact CG2-OE1 3.27Å; T491-E495 WeakPolarHBondContact CG2-OE1 3.46Å; T491-E495 WeakPolarHBondContact O-CG 3.43Å; T491-E495 PolarHBondContact O-N 2.67Å; T491-E495 VanDerWaalsContact O-N 3.09Å; V492-E495 PolarHBondContact O-N 3.47Å; I493-E495 PolarHBondContact O-N 2.63Å; E495-K497 VanDerWaalsContact C-N 3.34Å; E495-R539 IonicContact OE1-CZ 2.85Å; E495-R539 IonicContact OE1-NH1 2.99Å; E495-R539 PolarHBondContact OE1-NH1 2.86Å; E495-R539 IonicContact OE1-NH2 2.66Å; E495-R539 PolarHBondContact OE1-NH2 2.73Å; E495-R539 IonicContact OE2-CZ 3.08Å; E495-R539 IonicContact OE2-NH1 3.67Å; E495-R539 PolarHBondContact OE2-NH1 3.06Å; E495-R539 IonicContact OE2-NH2 2.68Å
496A94.5Very high93.2Very high47 Ų4748 Ų4839%0.38825%0.249SC..Hα-helixtrans-72.2-28.3174.500000113V492 I493 L529 L533V492-A496 PolarHBondContact O-N 3.16Å; V492-A496 VanDerWaalsContact O-N 3.11Å; I493-A496 PolarHBondContact O-N 3.41Å; A496-L529 HydrophobicContact CB-CD1 4.04Å; A496-L529 HydrophobicContact CB-CD2 4.3Å; A496-L533 HydrophobicContact CB-CD1 4.11Å; A496-L533 HydrophobicContact CB-CD2 3.81Å
497K94.9Very high92.7Very high72 Ų7251.8 Ų51.831%0.31328%0.283SS..  trans-155.783.7-173.8-164.9164.2174.7-174.90111.8I493 E495 E499 L500 L529I493-K497 PolarHBondContact O-N 3.13Å; E495-K497 VanDerWaalsContact C-N 3.34Å; K497-E499 WeakPolarHBondContact CE-OE1 3.43Å; K497-E499 HydrophobicContact CG-CG 4.33Å; K497-E499 VanDerWaalsContact CG-OE1 3.29Å; K497-E499 WeakPolarHBondContact CG-OE1 3.39Å; K497-E499 WeakPolarHBondContact CG-OE2 3.41Å; K497-E499 PolarHBondContact O-N 2.66Å; K497-E499 VanDerWaalsContact O-N 3.08Å; K497-L500 HydrophobicContact CB-CD1 4.27Å; K497-L500 HydrophobicContact CB-CG 4.32Å; K497-L500 HydrophobicContact CD-CD1 3.69Å; K497-L500 HydrophobicContact CD-CG 3.84Å; K497-L500 HydrophobicContact CG-CD1 4.14Å; K497-L500 HydrophobicContact CG-CG 3.92Å; K497-L500 PolarHBondContact O-N 3.08Å; K497-L529 HydrophobicContact CB-CD2 4.26Å; K497-L529 HydrophobicContact CD-CD2 4.3Å
498P92.4Very high92.4Very high98 Ų9852.8 Ų52.864%0.63629%0.288SS*.THydrogen-bonded Turntrans-57.8-24.2-169.9-27.935.8000116.6R494 L500R494-P498 WeakPolarHBondContact O-CA 3.36Å; R494-P498 WeakPolarHBondContact O-CG 3.03Å; P498-L500 VanDerWaalsContact C-N 3.33Å
499E92.4Very high92Very high135 Ų13562.1 Ų62.163%0.63133%0.329SS*.THydrogen-bonded Turntrans-75.4-18.617674.8-83.7-156.200113.6K497 R501K497-E499 WeakPolarHBondContact CE-OE1 3.43Å; K497-E499 HydrophobicContact CG-CG 4.33Å; K497-E499 VanDerWaalsContact CG-OE1 3.29Å; K497-E499 WeakPolarHBondContact CG-OE1 3.39Å; K497-E499 WeakPolarHBondContact CG-OE2 3.41Å; K497-E499 PolarHBondContact O-N 2.66Å; K497-E499 VanDerWaalsContact O-N 3.08Å; E499-R501 VanDerWaalsContact C-N 3.26Å; E499-R501 PolarHBondContact O-N 2.68Å
500L90.4Very high91.7Very high40 Ų4069.5 Ų69.521%0.20936%0.361CS..  trans-80.571.5172.8-69.8-172.2000111.1I493 R494 K497 P498 P503 V527I493-L500 HydrophobicContact CG2-CB 3.77Å; I493-L500 HydrophobicContact CG2-CD1 4.12Å; R494-L500 WeakPolarHBondContact CG-O 3.48Å; K497-L500 HydrophobicContact CB-CD1 4.27Å; K497-L500 HydrophobicContact CB-CG 4.32Å; K497-L500 HydrophobicContact CD-CD1 3.69Å; K497-L500 HydrophobicContact CD-CG 3.84Å; K497-L500 HydrophobicContact CG-CD1 4.14Å; K497-L500 HydrophobicContact CG-CG 3.92Å; K497-L500 PolarHBondContact O-N 3.08Å; P498-L500 VanDerWaalsContact C-N 3.33Å; L500-P503 HydrophobicContact CB-CG 4.4Å; L500-P503 WeakPolarHBondContact O-CD 3.37Å; L500-V527 HydrophobicContact CD1-CB 4.18Å; L500-V527 HydrophobicContact CD1-CG2 4.32Å; L500-V527 WeakPolarHBondContact CD1-O 3.44Å
501R91.2Very high91.4Very high104 Ų10469.6 Ų69.639%0.39236%0.362SS..  trans-86.9123171.3-175.9173.3-176.9158.111.2111.2E36 E40 E499 P503E36-R501 IonicContact OE1-CZ 2.88Å; E36-R501 IonicContact OE1-NE 3.63Å; E36-R501 PolarHBondContact OE1-NE 3.28Å; E36-R501 IonicContact OE1-NH2 3.22Å; E36-R501 PolarHBondContact OE1-NH2 3.05Å; E36-R501 IonicContact OE2-NE 2.69Å; E36-R501 IonicContact OE2-NH2 3.9Å; E36-R501 PolarHBondContact OE2-NH2 3.38Å; E40-R501 IonicContact OE1-CZ 3.78Å; E40-R501 IonicContact OE1-NH1 2.82Å; E40-R501 IonicContact OE1-NH2 3.62Å; E40-R501 PolarHBondContact OE1-NH2 3.43Å; E40-R501 IonicContact OE2-CZ 2.72Å; E40-R501 IonicContact OE2-NH1 3.62Å; E40-R501 IonicContact OE2-NH2 3.26Å; E40-R501 PolarHBondContact OE2-NH2 2.93Å; E499-R501 VanDerWaalsContact C-N 3.26Å; E499-R501 PolarHBondContact O-N 2.68Å; R501-P503 VanDerWaalsContact C-CD 3.47Å
502R90.8Very high91.1Very high97 Ų9771.9 Ų71.937%0.36637%0.372SS..SBendtrans54.345.5-179.9-58.1176.5-72.5-121.92.9115.1I35 E36 E490I35-R502 HydrophobicContact CD1-CB 4.03Å; I35-R502 HydrophobicContact CD1-CG 4Å; I35-R502 HydrophobicContact CG1-CG 4.34Å; E36-R502 HydrophobicContact CG-CG 3.91Å; E36-R502 IonicContact OE1-CZ 2.85Å; E36-R502 IonicContact OE1-NH1 2.8Å; E36-R502 WeakPolarHBondContact OE2-CD 3.26Å; E36-R502 IonicContact OE2-CZ 3.83Å; E36-R502 IonicContact OE2-NE 2.72Å; E36-R502 IonicContact OE2-NH1 3.43Å; E36-R502 PolarHBondContact OE2-NH1 2.89Å; E490-R502 VanDerWaalsContact OE1-CA 3.31Å; E490-R502 WeakPolarHBondContact OE1-CA 3.38Å; E490-R502 PolarHBondContact OE1-N 3.49Å
503P88.4Confident91Very high21 Ų2177 Ų7714%0.13640%0.398CS..  trans-63.3140.6175.229.4-36.1000111.4R486 E490 I493 L500 R501 V505 V527R486-P503 PolarHBondContact NH2-O 2.93Å; R486-P503 VanDerWaalsContact NH2-O 3.11Å; E490-P503 WeakPolarHBondContact OE2-CD 3.44Å; I493-P503 HydrophobicContact CD1-CG 4.28Å; I493-P503 HydrophobicContact CG2-CG 4.05Å; L500-P503 HydrophobicContact CB-CG 4.4Å; L500-P503 WeakPolarHBondContact O-CD 3.37Å; R501-P503 VanDerWaalsContact C-CD 3.47Å; P503-V505 PolarHBondContact O-N 3.26Å; P503-V527 HydrophobicContact CB-CB 4.34Å; P503-V527 HydrophobicContact CB-CG1 3.7Å; P503-V527 HydrophobicContact CG-CB 4.46Å; P503-V527 HydrophobicContact CG-CG1 3.85Å
504G85Confident91Very high61 Ų6179 Ų7963%0.62941%0.409SS*.  trans-71.296177.700000111.6Q506G504-Q506 PolarHBondContact O-N 3.12Å
505V86.3Confident91Very high7 Ų780.2 Ų80.24%0.04242%0.424CS..  trans-85.4103.3176.9-175.70000108.2L489 I493 P503 R526 V527L489-V505 HydrophobicContact CD2-CG1 4.28Å; I493-V505 HydrophobicContact CD1-CG2 4.25Å; P503-V505 PolarHBondContact O-N 3.26Å; V505-R526 HydrophobicContact CG1-CB 4.47Å; V505-V527 HydrophobicContact CG2-CG1 3.82Å
506Q85.4Confident91.2Very high148 Ų14876.1 Ų76.169%0.69240%0.404SS*.PPolyproline II helixtrans-47.1145.9175.9-64.8177.6-7.100111.6G504 I508 R526G504-Q506 PolarHBondContact O-N 3.12Å; Q506-I508 PolarHBondContact O-N 3.25Å; Q506-R526 VanDerWaalsContact C-NH1 3.33Å; Q506-R526 PolarHBondContact O-NH1 3.01Å
507A87.1Confident91.3Very high93 Ų9378 Ų7877%0.76941%0.411SS*.PPolyproline II helixtrans-58.8135.8-175.100000113.6R526A507-R526 PolarHBondContact O-NH1 3.15Å
508I91Very high91.3Very high21 Ų2177.2 Ų77.211%0.10841%0.409CS..PPolyproline II helixtrans-96.3120.7173.9-68162.7000108.4Q506 K510 A511 L514 Y519 L522 R526Q506-I508 PolarHBondContact O-N 3.25Å; I508-K510 PolarHBondContact O-N 3.05Å; I508-A511 HydrophobicContact CB-CB 3.99Å; I508-A511 HydrophobicContact CG2-CB 3.92Å; I508-A511 WeakPolarHBondContact O-CB 3.36Å; I508-A511 PolarHBondContact O-N 3.28Å; I508-L514 HydrophobicContact CG2-CD1 3.9Å; I508-Y519 HydrophobicContact CB-CD2 4.33Å; I508-Y519 HydrophobicContact CB-CE2 4.17Å; I508-Y519 HydrophobicContact CD1-CD2 3.67Å; I508-Y519 HydrophobicContact CD1-CE2 3.54Å; I508-Y519 HydrophobicContact CD1-CG 4.49Å; I508-Y519 WeakPolarHBondContact CD1-O 3.28Å; I508-Y519 HydrophobicContact CG1-CE2 4.35Å; I508-Y519 HydrophobicContact CG2-CD2 4.39Å; I508-L522 HydrophobicContact CD1-CB 3.95Å; I508-L522 HydrophobicContact CG1-CB 4.38Å; I508-L522 HydrophobicContact CG2-CB 4.49Å; I508-L522 HydrophobicContact CG2-CD1 4.1Å; I508-R526 VanDerWaalsContact CG1-CZ 3.45Å
509K90.6Very high91.5Very high197 Ų19772.9 Ų72.986%0.85738%0.38SS*.THydrogen-bonded Turntrans-61.2133-178.2-67.5-176.9179.6178.30110.4A511K509-A511 PolarHBondContact O-N 2.98Å; K509-A511 VanDerWaalsContact O-N 3.13Å
510K90Very high91.8Very high155 Ų15566.5 Ų66.567%0.67435%0.35SS*.THydrogen-bonded Turntrans53.126.3-179.6-61-174.6175.3-174.80115I508 H512 L513I508-K510 PolarHBondContact O-N 3.05Å; K510-H512 PolarHBondContact O-N 3.28Å; K510-L513 HydrophobicContact CB-CD1 4.16Å; K510-L513 HydrophobicContact CB-CG 4.47Å; K510-L513 HydrophobicContact CD-CD1 4.15Å; K510-L513 WeakPolarHBondContact O-CB 3.47Å; K510-L513 PolarHBondContact O-N 2.91Å
511A90.4Very high92.1Very high2 Ų270 Ų702%0.01736%0.361CS..G310 helixtrans-52.6-28.7-175.800000115.8M482 I508 K509 L513 L514 Y519M482-A511 HydrophobicContact CE-CB 3.5Å; M482-A511 VanDerWaalsContact CE-CB 3.5Å; M482-A511 HydrophobicContact SD-CB 3.58Å; M482-A511 VanDerWaalsContact SD-CB 3.58Å; I508-A511 HydrophobicContact CB-CB 3.99Å; I508-A511 HydrophobicContact CG2-CB 3.92Å; I508-A511 WeakPolarHBondContact O-CB 3.36Å; I508-A511 PolarHBondContact O-N 3.28Å; K509-A511 PolarHBondContact O-N 2.98Å; K509-A511 VanDerWaalsContact O-N 3.13Å; A511-L513 PolarHBondContact O-N 3.49Å; A511-L514 WeakPolarHBondContact O-CB 3.36Å; A511-L514 PolarHBondContact O-N 2.84Å; A511-L514 VanDerWaalsContact O-N 3.08Å; A511-Y519 HydrophobicContact CB-CD2 3.66Å; A511-Y519 HydrophobicContact CB-CE2 3.79Å
512H91.5Very high92.3Very high51 Ų5167.8 Ų67.824%0.23636%0.356CS..G310 helixtrans-63.6-21.1175.856-91.3000114.2G478 L479 R481 M482 K510G478-H512 WeakPolarHBondContact O-CB 3.38Å; L479-H512 HydrophobicContact CD2-CB 4.42Å; L479-H512 VanDerWaalsContact CD2-ND1 3.31Å; L479-H512 WeakPolarHBondContact CD2-ND1 3.47Å; R481-H512 PolarHBondContact NH1-O 3.02Å; M482-H512 HydrophobicContact SD-CB 4.2Å; K510-H512 PolarHBondContact O-N 3.28Å
513L94.4Very high92.6Very high120 Ų12063.1 Ų63.163%0.62834%0.339SS*.G310 helixtrans-89.1-7.2175.3-54.6-178.4000113.2K510 A511K510-L513 HydrophobicContact CB-CD1 4.16Å; K510-L513 HydrophobicContact CB-CG 4.47Å; K510-L513 HydrophobicContact CD-CD1 4.15Å; K510-L513 WeakPolarHBondContact O-CB 3.47Å; K510-L513 PolarHBondContact O-N 2.91Å; A511-L513 PolarHBondContact O-N 3.49Å
514L95.4Very high93Very high41 Ų4162.2 Ų62.222%0.21533%0.333CS..SBendtrans-91.9145.2-178.1-57.2179.2000110.6Y485 I508 A511 E518 L522Y485-L514 WeakPolarHBondContact CE2-O 3.26Å; Y485-L514 PolarHBondContact OH-O 3.31Å; I508-L514 HydrophobicContact CG2-CD1 3.9Å; A511-L514 WeakPolarHBondContact O-CB 3.36Å; A511-L514 PolarHBondContact O-N 2.84Å; A511-L514 VanDerWaalsContact O-N 3.08Å; L514-E518 HydrophobicContact CB-CB 4.5Å; L514-E518 HydrophobicContact CB-CG 4.49Å; L514-E518 HydrophobicContact CD1-CG 4.28Å; L514-E518 HydrophobicContact CD2-CG 4.11Å; L514-L522 HydrophobicContact CD1-CD1 3.81Å
515P95.8Very high93.5Very high80 Ų8062.5 Ų62.552%0.51932%0.323SS..  trans-58.6149158.5-20.332.9000110.6T517 E518 Y519P515-T517 PolarHBondContact O-N 3.36Å; P515-E518 PolarHBondContact O-N 3.07Å; P515-E518 VanDerWaalsContact O-N 3.14Å; P515-Y519 PolarHBondContact O-N 3.27Å
516F96.9Very high93.9Very high8 Ų866.7 Ų66.74%0.03534%0.338CS..Hα-helixtrans-57.3-33.9-179.9176.5-94.9000113.4Y485 T488 L489 Y519 A520 L535 V540 L544Y485-F516 HydrophobicContact CD1-CD2 4.24Å; Y485-F516 HydrophobicContact CD2-CD2 4.19Å; Y485-F516 HydrophobicContact CE1-CB 4.32Å; Y485-F516 HydrophobicContact CE2-CB 4.21Å; Y485-F516 HydrophobicContact CG-CD2 4.02Å; Y485-F516 PolarHBondContact OH-N 3.39Å; T488-F516 HydrophobicContact CG2-CD1 4.45Å; T488-F516 HydrophobicContact CG2-CD2 4.4Å; T488-F516 HydrophobicContact CG2-CE1 3.79Å; T488-F516 HydrophobicContact CG2-CE2 3.75Å; T488-F516 HydrophobicContact CG2-CZ 3.4Å; T488-F516 VanDerWaalsContact CG2-CZ 3.4Å; L489-F516 HydrophobicContact CB-CE2 4.25Å; L489-F516 HydrophobicContact CB-CZ 4.35Å; F516-Y519 HydrophobicContact CD2-CD1 4.01Å; F516-Y519 AromaticContact CE2-CD1 4Å; F516-Y519 HydrophobicContact CE2-CD1 4Å; F516-Y519 HydrophobicContact CE2-CE1 4.44Å; F516-Y519 WeakPolarHBondContact O-CB 3.19Å; F516-Y519 PolarHBondContact O-N 3.11Å; F516-A520 HydrophobicContact CE1-CB 4.1Å; F516-A520 HydrophobicContact CZ-CB 4.17Å; F516-A520 WeakPolarHBondContact O-CB 3.11Å; F516-A520 PolarHBondContact O-N 3.11Å; F516-L535 HydrophobicContact CE1-CD1 4.38Å; F516-V540 HydrophobicContact CD1-CG1 3.39Å; F516-V540 HydrophobicContact CE1-CG1 3.6Å; F516-V540 HydrophobicContact CE1-CG2 4.16Å; F516-V540 HydrophobicContact CG-CG1 4.3Å; F516-L544 HydrophobicContact CB-CD1 3.59Å; F516-L544 HydrophobicContact CB-CD2 4.32Å; F516-L544 HydrophobicContact CD1-CD1 4.24Å; F516-L544 HydrophobicContact CD2-CD2 4.08Å; F516-L544 HydrophobicContact CG-CD1 3.85Å; F516-L544 HydrophobicContact CG-CD2 4.21Å
517T96.2Very high94.3Very high86 Ų8660.8 Ų60.853%0.52831%0.312SS..Hα-helixtrans-60.9-45.8177.146.50000112.2P515 A520 R521 L535P515-T517 PolarHBondContact O-N 3.36Å; T517-A520 PolarHBondContact O-N 2.01Å; T517-R521 WeakPolarHBondContact O-CB 3.22Å; T517-R521 PolarHBondContact O-N 3.46Å; T517-L535 HydrophobicContact CG2-CD1 4.36Å
518E96.6Very high94.7Very high57 Ų5759.5 Ų59.527%0.26631%0.308SS..Hα-helixtrans-69.1-38.2175.6178.758.8-163.800111.5L514 P515 A520 R521 L522L514-E518 HydrophobicContact CB-CB 4.5Å; L514-E518 HydrophobicContact CB-CG 4.49Å; L514-E518 HydrophobicContact CD1-CG 4.28Å; L514-E518 HydrophobicContact CD2-CG 4.11Å; P515-E518 PolarHBondContact O-N 3.07Å; P515-E518 VanDerWaalsContact O-N 3.14Å; E518-A520 PolarHBondContact O-N 3.04Å; E518-R521 PolarHBondContact O-N 3.03Å; E518-R521 IonicContact OE1-CZ 3.66Å; E518-R521 IonicContact OE1-NE 3.89Å; E518-R521 IonicContact OE1-NH2 2.71Å; E518-R521 PolarHBondContact OE1-NH2 3.06Å; E518-R521 IonicContact OE2-CZ 3.25Å; E518-R521 IonicContact OE2-NE 3.51Å; E518-R521 PolarHBondContact OE2-NE 3.42Å; E518-R521 IonicContact OE2-NH2 3.99Å; E518-R521 PolarHBondContact OE2-NH2 3.25Å; E518-L522 HydrophobicContact CG-CD1 4.32Å; E518-L522 WeakPolarHBondContact O-CG 3.22Å; E518-L522 PolarHBondContact O-N 3.38Å
519Y96.9Very high94.9Very high6 Ų659.4 Ų59.42%0.02431%0.308CS..Hα-helixtrans-59.5-44.7172.8174-100.4000112.3M482 Y485 R486 L489 I508 A511 P515 F516 L522 G523M482-Y519 HydrophobicContact CE-CE2 3.77Å; Y485-Y519 AromaticContact CD2-CD1 3.75Å; Y485-Y519 HydrophobicContact CD2-CD1 3.75Å; Y485-Y519 HydrophobicContact CD2-CD2 4.19Å; Y485-Y519 HydrophobicContact CD2-CE1 4.32Å; Y485-Y519 AromaticContact CD2-CG 3.68Å; Y485-Y519 HydrophobicContact CD2-CG 3.68Å; Y485-Y519 HydrophobicContact CE2-CG 4.37Å; Y485-Y519 HydrophobicContact CG-CD1 4.26Å; R486-Y519 WeakPolarHBondContact CD-OH 3.45Å; R486-Y519 WeakPolarHBondContact CG-OH 3.45Å; L489-Y519 HydrophobicContact CB-CE1 4.09Å; L489-Y519 HydrophobicContact CD2-CD1 4.4Å; L489-Y519 HydrophobicContact CD2-CE1 3.66Å; L489-Y519 HydrophobicContact CG-CE1 4.49Å; I508-Y519 HydrophobicContact CB-CD2 4.33Å; I508-Y519 HydrophobicContact CB-CE2 4.17Å; I508-Y519 HydrophobicContact CD1-CD2 3.67Å; I508-Y519 HydrophobicContact CD1-CE2 3.54Å; I508-Y519 HydrophobicContact CD1-CG 4.49Å; I508-Y519 WeakPolarHBondContact CD1-O 3.28Å; I508-Y519 HydrophobicContact CG1-CE2 4.35Å; I508-Y519 HydrophobicContact CG2-CD2 4.39Å; A511-Y519 HydrophobicContact CB-CD2 3.66Å; A511-Y519 HydrophobicContact CB-CE2 3.79Å; P515-Y519 PolarHBondContact O-N 3.27Å; F516-Y519 HydrophobicContact CD2-CD1 4.01Å; F516-Y519 AromaticContact CE2-CD1 4Å; F516-Y519 HydrophobicContact CE2-CD1 4Å; F516-Y519 HydrophobicContact CE2-CE1 4.44Å; F516-Y519 WeakPolarHBondContact O-CB 3.19Å; F516-Y519 PolarHBondContact O-N 3.11Å; Y519-L522 PolarHBondContact O-N 3.12Å; Y519-G523 PolarHBondContact O-N 3.25Å
520A97.1Very high95.2Very high1 Ų152.9 Ų52.91%0.00829%0.286CS..Hα-helixtrans-65.5-45.1175.900000111.5L489 F516 T517 E518 L522 G523 L524 L535L489-A520 HydrophobicContact CD1-CB 4.2Å; F516-A520 HydrophobicContact CE1-CB 4.1Å; F516-A520 HydrophobicContact CZ-CB 4.17Å; F516-A520 WeakPolarHBondContact O-CB 3.11Å; F516-A520 PolarHBondContact O-N 3.11Å; T517-A520 PolarHBondContact O-N 2.01Å; E518-A520 PolarHBondContact O-N 3.04Å; A520-L522 PolarHBondContact O-N 2.85Å; A520-G523 WeakPolarHBondContact O-CA 3.25Å; A520-G523 PolarHBondContact O-N 2.88Å; A520-L524 HydrophobicContact CB-CD1 4.42Å; A520-L524 WeakPolarHBondContact O-CG 3.45Å; A520-L524 PolarHBondContact O-N 3.06Å; A520-L535 HydrophobicContact CB-CD1 4.16Å
521R96.9Very high95.5Very high115 Ų11548.2 Ų48.243%0.43427%0.271SS..Hα-helixtrans-55.7-35.6175.9-166-173.773.480.83.8112.9T517 E518 P525 P531T517-R521 WeakPolarHBondContact O-CB 3.22Å; T517-R521 PolarHBondContact O-N 3.46Å; E518-R521 PolarHBondContact O-N 3.03Å; E518-R521 IonicContact OE1-CZ 3.66Å; E518-R521 IonicContact OE1-NE 3.89Å; E518-R521 IonicContact OE1-NH2 2.71Å; E518-R521 PolarHBondContact OE1-NH2 3.06Å; E518-R521 IonicContact OE2-CZ 3.25Å; E518-R521 IonicContact OE2-NE 3.51Å; E518-R521 PolarHBondContact OE2-NE 3.42Å; E518-R521 IonicContact OE2-NH2 3.99Å; E518-R521 PolarHBondContact OE2-NH2 3.25Å; R521-P525 VanDerWaalsContact O-CD 3.23Å; R521-P525 WeakPolarHBondContact O-CD 3.38Å; R521-P531 WeakPolarHBondContact CA-O 3.46Å; R521-P531 HydrophobicContact CG-CB 3.8Å; R521-P531 WeakPolarHBondContact CG-O 3.47Å; R521-P531 WeakPolarHBondContact O-CB 3.23Å
522L96.7Very high95.7Very high56 Ų5654.4 Ų54.429%0.29330%0.304SS..Hα-helixtrans-84.5-16.2175.4-66175.9000114I508 L514 E518 Y519 A520 R526I508-L522 HydrophobicContact CD1-CB 3.95Å; I508-L522 HydrophobicContact CG1-CB 4.38Å; I508-L522 HydrophobicContact CG2-CB 4.49Å; I508-L522 HydrophobicContact CG2-CD1 4.1Å; L514-L522 HydrophobicContact CD1-CD1 3.81Å; E518-L522 HydrophobicContact CG-CD1 4.32Å; E518-L522 WeakPolarHBondContact O-CG 3.22Å; E518-L522 PolarHBondContact O-N 3.38Å; Y519-L522 PolarHBondContact O-N 3.12Å; A520-L522 PolarHBondContact O-N 2.85Å; L522-R526 PolarHBondContact O-NE 3.29Å
523G95.8Very high95.9Very high0 Ų053.5 Ų53.50%030%0.301CS..Hα-helixtrans-94.6-44.6-177.200000114Y519 A520 R526Y519-G523 PolarHBondContact O-N 3.25Å; A520-G523 WeakPolarHBondContact O-CA 3.25Å; A520-G523 PolarHBondContact O-N 2.88Å; G523-R526 WeakPolarHBondContact O-CB 3.36Å; G523-R526 WeakPolarHBondContact O-CG 3.48Å; G523-R526 PolarHBondContact O-N 3.38Å
524L96.5Very high95.9Very high2 Ų253.6 Ų53.61%0.0131%0.308CS..G310 helixtrans-56.9-41.6-176.2-68.9164.2000114L489 V492 I493 A520 R526 V527 G528 L529 P530 L533L489-L524 HydrophobicContact CD1-CD2 3.96Å; L489-L524 HydrophobicContact CD1-CG 4.09Å; V492-L524 HydrophobicContact CG1-CD2 4.3Å; I493-L524 HydrophobicContact CG1-CD2 3.87Å; A520-L524 HydrophobicContact CB-CD1 4.42Å; A520-L524 WeakPolarHBondContact O-CG 3.45Å; A520-L524 PolarHBondContact O-N 3.06Å; L524-R526 PolarHBondContact O-N 3.12Å; L524-R526 VanDerWaalsContact O-N 3.14Å; L524-V527 VanDerWaalsContact O-CG2 3.24Å; L524-V527 WeakPolarHBondContact O-CG2 3.48Å; L524-V527 PolarHBondContact O-N 2.71Å; L524-V527 VanDerWaalsContact O-N 3.08Å; L524-G528 PolarHBondContact O-N 2.93Å; L524-L529 CarbonylContact C-O 3.2Å; L524-L529 HydrophobicContact CB-CB 4.03Å; L524-L529 HydrophobicContact CD2-CB 4.05Å; L524-L529 HydrophobicContact CD2-CD1 3.86Å; L524-L529 PolarHBondContact O-N 3.1Å; L524-P530 WeakPolarHBondContact CB-O 3.16Å; L524-L533 HydrophobicContact CD1-CB 3.75Å; L524-L533 HydrophobicContact CD1-CD2 3.94Å; L524-L533 HydrophobicContact CD2-CD2 3.86Å
525P96.4Very high95.9Very high67 Ų6753.6 Ų53.644%0.43531%0.308SS..G310 helixtrans-61.3-24.6175.6-26.436.9000114R521 V527 G528 L529 P531R521-P525 VanDerWaalsContact O-CD 3.23Å; R521-P525 WeakPolarHBondContact O-CD 3.38Å; P525-V527 PolarHBondContact O-N 3.24Å; P525-G528 PolarHBondContact O-N 3.23Å; P525-L529 WeakPolarHBondContact CA-O 3.39Å; P525-P531 HydrophobicContact CG-CB 3.82Å; P525-P531 HydrophobicContact CG-CG 4.43Å
526R94.9Very high95.8Very high94 Ų9454 Ų5436%0.35531%0.306SS..G310 helixtrans-71.1-13.5179.5-51.4176.9-176.8-126.6-19112.8V505 Q506 A507 I508 L522 G523 L524V505-R526 HydrophobicContact CG1-CB 4.47Å; Q506-R526 VanDerWaalsContact C-NH1 3.33Å; Q506-R526 PolarHBondContact O-NH1 3.01Å; A507-R526 PolarHBondContact O-NH1 3.15Å; I508-R526 VanDerWaalsContact CG1-CZ 3.45Å; L522-R526 PolarHBondContact O-NE 3.29Å; G523-R526 WeakPolarHBondContact O-CB 3.36Å; G523-R526 WeakPolarHBondContact O-CG 3.48Å; G523-R526 PolarHBondContact O-N 3.38Å; L524-R526 PolarHBondContact O-N 3.12Å; L524-R526 VanDerWaalsContact O-N 3.14Å
527V93.8Very high95.7Very high24 Ų2458.9 Ų58.915%0.14534%0.337CS..G310 helixtrans-118.111.9176.9-53.60000112.5I493 L500 P503 V505 L524 P525 L529I493-V527 HydrophobicContact CD1-CG1 4.32Å; I493-V527 HydrophobicContact CD1-CG2 3.94Å; I493-V527 HydrophobicContact CG1-CG2 4.07Å; I493-V527 HydrophobicContact CG2-CG2 4.28Å; L500-V527 HydrophobicContact CD1-CB 4.18Å; L500-V527 HydrophobicContact CD1-CG2 4.32Å; L500-V527 WeakPolarHBondContact CD1-O 3.44Å; P503-V527 HydrophobicContact CB-CB 4.34Å; P503-V527 HydrophobicContact CB-CG1 3.7Å; P503-V527 HydrophobicContact CG-CB 4.46Å; P503-V527 HydrophobicContact CG-CG1 3.85Å; V505-V527 HydrophobicContact CG2-CG1 3.82Å; L524-V527 VanDerWaalsContact O-CG2 3.24Å; L524-V527 WeakPolarHBondContact O-CG2 3.48Å; L524-V527 PolarHBondContact O-N 2.71Å; L524-V527 VanDerWaalsContact O-N 3.08Å; P525-V527 PolarHBondContact O-N 3.24Å; V527-L529 HydrophobicContact CG2-CB 4.26Å; V527-L529 HydrophobicContact CG2-CD1 3.99Å; V527-L529 HydrophobicContact CG2-CG 4.05Å
528G94.6Very high95.7Very high66 Ų6659.3 Ų59.368%0.6834%0.342SS*.THydrogen-bonded Turntrans75.624-179.600000114.8L524 P525L524-G528 PolarHBondContact O-N 2.93Å; P525-G528 PolarHBondContact O-N 3.23Å
529L95.9Very high95.6Very high20 Ų2061.9 Ų61.911%0.10535%0.349CS..  trans-104.5151.6172.8-70.2177.6000111.2I493 A496 K497 L524 P525 V527I493-L529 HydrophobicContact CB-CD1 4.29Å; I493-L529 HydrophobicContact CG1-CD1 4.09Å; I493-L529 HydrophobicContact CG2-CD1 4.04Å; A496-L529 HydrophobicContact CB-CD1 4.04Å; A496-L529 HydrophobicContact CB-CD2 4.3Å; K497-L529 HydrophobicContact CB-CD2 4.26Å; K497-L529 HydrophobicContact CD-CD2 4.3Å; L524-L529 CarbonylContact C-O 3.2Å; L524-L529 HydrophobicContact CB-CB 4.03Å; L524-L529 HydrophobicContact CD2-CB 4.05Å; L524-L529 HydrophobicContact CD2-CD1 3.86Å; L524-L529 PolarHBondContact O-N 3.1Å; P525-L529 WeakPolarHBondContact CA-O 3.39Å; V527-L529 HydrophobicContact CG2-CB 4.26Å; V527-L529 HydrophobicContact CG2-CD1 3.99Å; V527-L529 HydrophobicContact CG2-CG 4.05Å
530P96.9Very high95.7Very high60 Ų6062.2 Ų62.239%0.3935%0.352SS..  trans-63.4142.6-179.424.3-32.2000111.7L524 D532 L533L524-P530 WeakPolarHBondContact CB-O 3.16Å; P530-D532 PolarHBondContact O-N 3.32Å; P530-L533 HydrophobicContact CG-CB 4.18Å; P530-L533 HydrophobicContact CG-CD1 4.19Å; P530-L533 WeakPolarHBondContact O-CB 3.45Å; P530-L533 PolarHBondContact O-N 2.81Å
531P96.1Very high95.7Very high57 Ų5763 Ų6337%0.3736%0.36SS..THydrogen-bonded Turntrans-66.3-28.1179.128-34.2000112.6R521 P525R521-P531 WeakPolarHBondContact CA-O 3.46Å; R521-P531 HydrophobicContact CG-CB 3.8Å; R521-P531 WeakPolarHBondContact CG-O 3.47Å; R521-P531 WeakPolarHBondContact O-CB 3.23Å; P525-P531 HydrophobicContact CG-CB 3.82Å; P525-P531 HydrophobicContact CG-CG 4.43Å
532D94.7Very high95.8Very high131 Ų13159.3 Ų59.370%0.70136%0.355SS*.THydrogen-bonded Turntrans-97.517.4-177.558.2-44.5000113.3P530P530-D532 PolarHBondContact O-N 3.32Å
533L95Very high95.8Very high33 Ų3357.3 Ų57.317%0.17334%0.344CS..  trans-47.8124.5172.5-17670.8000111V492 A496 L524 P530 L535V492-L533 HydrophobicContact CG1-CD2 3.79Å; A496-L533 HydrophobicContact CB-CD1 4.11Å; A496-L533 HydrophobicContact CB-CD2 3.81Å; L524-L533 HydrophobicContact CD1-CB 3.75Å; L524-L533 HydrophobicContact CD1-CD2 3.94Å; L524-L533 HydrophobicContact CD2-CD2 3.86Å; P530-L533 HydrophobicContact CG-CB 4.18Å; P530-L533 HydrophobicContact CG-CD1 4.19Å; P530-L533 WeakPolarHBondContact O-CB 3.45Å; P530-L533 PolarHBondContact O-N 2.81Å; L533-L535 PolarHBondContact O-N 2.9Å
534P94.4Very high95.9Very high121 Ų12159.2 Ų59.279%0.78635%0.354SS*.  trans-58125.9178.4-27.436.1000112.3
535L95.3Very high96Very high42 Ų4268 Ų6822%0.2239%0.387CS..  trans-105.8129.9178.6-56.2-178.7000110.2V492 F516 T517 A520 L533 T537V492-L535 HydrophobicContact CG1-CD2 3.61Å; V492-L535 HydrophobicContact CG2-CD2 4.2Å; F516-L535 HydrophobicContact CE1-CD1 4.38Å; T517-L535 HydrophobicContact CG2-CD1 4.36Å; A520-L535 HydrophobicContact CB-CD1 4.16Å; L533-L535 PolarHBondContact O-N 2.9Å; L535-T537 PolarHBondContact O-N 3.33Å
536D94.9Very high96Very high87 Ų8767.4 Ų67.447%0.46538%0.378SS..  trans-6798165.1177.7-14.1000109C538 R539 V540D536-C538 VanDerWaalsContact C-N 3.25Å; D536-C538 PolarHBondContact O-N 3.13Å; D536-C538 WeakPolarHBondContact OD1-CA 3.08Å; D536-C538 WeakPolarHBondContact OD1-CB 3.46Å; D536-C538 PolarHBondContact OD1-N 3.27Å; D536-R539 HydrophobicContact CB-CB 4.1Å; D536-R539 PolarHBondContact O-N 3.11Å; D536-R539 PolarHBondContact OD1-N 3.47Å; D536-R539 WeakPolarHBondContact OD2-CB 3.38Å; D536-V540 WeakPolarHBondContact O-CB 3.4Å; D536-V540 VanDerWaalsContact O-CG2 3.24Å; D536-V540 WeakPolarHBondContact O-CG2 3.45Å; D536-V540 PolarHBondContact O-N 2.69Å
537T94.2Very high96.1Very high111 Ų11165.6 Ų65.668%0.68137%0.374SS*.Hα-helixtrans-66-26.7-177.555.90000112.9L535 G541L535-T537 PolarHBondContact O-N 3.33Å; T537-G541 PolarHBondContact O-N 2.82Å
538C95.8Very high96.3Very high95 Ų9566.2 Ų66.264%0.64239%0.385SS*.Hα-helixtrans-71.2-50.1177.3-170.20000110.4D536 G541 A542D536-C538 VanDerWaalsContact C-N 3.25Å; D536-C538 PolarHBondContact O-N 3.13Å; D536-C538 WeakPolarHBondContact OD1-CA 3.08Å; D536-C538 WeakPolarHBondContact OD1-CB 3.46Å; D536-C538 PolarHBondContact OD1-N 3.27Å; C538-G541 PolarHBondContact O-N 3.21Å; C538-A542 PolarHBondContact O-N 3.46Å
539R95.9Very high96.4Very high111 Ų11167.3 Ų67.342%0.41937%0.369SS..Hα-helixtrans-75.1-37.3-177.9-170.4166.1166.4-113.3-13112.9E495 D536 G541 A542 M543E495-R539 IonicContact OE1-CZ 2.85Å; E495-R539 IonicContact OE1-NH1 2.99Å; E495-R539 PolarHBondContact OE1-NH1 2.86Å; E495-R539 IonicContact OE1-NH2 2.66Å; E495-R539 PolarHBondContact OE1-NH2 2.73Å; E495-R539 IonicContact OE2-CZ 3.08Å; E495-R539 IonicContact OE2-NH1 3.67Å; E495-R539 PolarHBondContact OE2-NH1 3.06Å; E495-R539 IonicContact OE2-NH2 2.68Å; D536-R539 HydrophobicContact CB-CB 4.1Å; D536-R539 PolarHBondContact O-N 3.11Å; D536-R539 PolarHBondContact OD1-N 3.47Å; D536-R539 WeakPolarHBondContact OD2-CB 3.38Å; R539-G541 VanDerWaalsContact C-N 3.33Å; R539-A542 WeakPolarHBondContact O-CB 3.44Å; R539-A542 PolarHBondContact O-N 3.2Å; R539-A542 VanDerWaalsContact O-N 3.17Å; R539-M543 HydrophobicContact CG-CE 4.43Å; R539-M543 PolarHBondContact O-N 2.84Å
540V97.6Very high96.5Very high13 Ų1366.3 Ų66.38%0.07936%0.364CS..Hα-helixtrans-58.6-45.8166.4165.20000110.4T488 V492 F516 D536 A542 M543 L544T488-V540 HydrophobicContact CG2-CG1 4.15Å; T488-V540 HydrophobicContact CG2-CG2 4.25Å; V492-V540 HydrophobicContact CG2-CG2 4.27Å; F516-V540 HydrophobicContact CD1-CG1 3.39Å; F516-V540 HydrophobicContact CE1-CG1 3.6Å; F516-V540 HydrophobicContact CE1-CG2 4.16Å; F516-V540 HydrophobicContact CG-CG1 4.3Å; D536-V540 WeakPolarHBondContact O-CB 3.4Å; D536-V540 VanDerWaalsContact O-CG2 3.24Å; D536-V540 WeakPolarHBondContact O-CG2 3.45Å; D536-V540 PolarHBondContact O-N 2.69Å; V540-A542 VanDerWaalsContact C-N 3.29Å; V540-A542 PolarHBondContact O-N 3.02Å; V540-M543 HydrophobicContact CG2-CE 4.38Å; V540-M543 PolarHBondContact O-N 3.02Å; V540-L544 HydrophobicContact CG1-CD1 3.77Å; V540-L544 HydrophobicContact CG1-CG 4.37Å; V540-L544 VanDerWaalsContact O-CG 3.29Å; V540-L544 WeakPolarHBondContact O-CG 3.26Å; V540-L544 PolarHBondContact O-N 3.37Å
541G97.8Very high96.6Very high18 Ų1863.7 Ų63.719%0.18635%0.347CS..Hα-helixtrans-60-36.917400000113.2T537 C538 R539 R545T537-G541 PolarHBondContact O-N 2.82Å; C538-G541 PolarHBondContact O-N 3.21Å; R539-G541 VanDerWaalsContact C-N 3.33Å; G541-R545 WeakPolarHBondContact O-CG 3.25Å; G541-R545 PolarHBondContact O-N 2.89Å; G541-R545 VanDerWaalsContact O-N 3.12Å; G541-R545 PolarHBondContact O-NH1 2.86Å
542A98Very high96.7Very high38 Ų3861 Ų6131%0.31433%0.329SS..Hα-helixtrans-70.6-36176.300000113.5C538 R539 V540C538-A542 PolarHBondContact O-N 3.46Å; R539-A542 WeakPolarHBondContact O-CB 3.44Å; R539-A542 PolarHBondContact O-N 3.2Å; R539-A542 VanDerWaalsContact O-N 3.17Å; V540-A542 VanDerWaalsContact C-N 3.29Å; V540-A542 PolarHBondContact O-N 3.02Å
543M98.3Very high96.9Very high14 Ų1454.8 Ų54.87%0.06930%0.296CS..Hα-helixtrans-66.2-49.2171.5-74-170.9-88.300111.2F38 T488 T491 R539 V540 R545 Q546F38-M543 HydrophobicContact CB-CG 4.37Å; F38-M543 HydrophobicContact CB-SD 3.82Å; F38-M543 HydrophobicContact CD1-CB 4.26Å; F38-M543 HydrophobicContact CD1-CG 3.84Å; F38-M543 HydrophobicContact CD1-SD 4.34Å; F38-M543 HydrophobicContact CD2-CB 4.13Å; F38-M543 HydrophobicContact CD2-CG 3.98Å; F38-M543 HydrophobicContact CD2-SD 3.65Å; F38-M543 HydrophobicContact CE1-CB 3.98Å; F38-M543 HydrophobicContact CE1-CG 4.07Å; F38-M543 HydrophobicContact CE2-CB 3.84Å; F38-M543 HydrophobicContact CE2-CG 4.21Å; F38-M543 HydrophobicContact CE2-SD 4.3Å; F38-M543 HydrophobicContact CG-CB 4.34Å; F38-M543 HydrophobicContact CG-CG 3.81Å; F38-M543 HydrophobicContact CG-SD 3.68Å; F38-M543 HydrophobicContact CZ-CB 3.77Å; F38-M543 HydrophobicContact CZ-CG 4.26Å; F38-M543 VanDerWaalsContact CZ-O 3.24Å; F38-M543 WeakPolarHBondContact CZ-O 3.38Å; T488-M543 HydrophobicContact CG2-CB 4.07Å; T488-M543 HydrophobicContact CG2-CE 3.87Å; T488-M543 HydrophobicContact CG2-SD 4.11Å; T491-M543 HydrophobicContact CG2-CE 4.05Å; T491-M543 HydrophobicContact CG2-SD 3.82Å; R539-M543 HydrophobicContact CG-CE 4.43Å; R539-M543 PolarHBondContact O-N 2.84Å; V540-M543 HydrophobicContact CG2-CE 4.38Å; V540-M543 PolarHBondContact O-N 3.02Å; M543-R545 VanDerWaalsContact C-N 3.29Å; M543-R545 PolarHBondContact O-N 3.39Å; M543-Q546 WeakPolarHBondContact O-CB 3.38Å; M543-Q546 PolarHBondContact O-N 3.39Å
544L97.7Very high97Very high40 Ų4054 Ų5421%0.20929%0.291CS..Hα-helixtrans-63.9-31-178-65.7171.3000113.2Y485 T488 F516 V540 Q546 E547Y485-L544 HydrophobicContact CD1-CD2 3.79Å; Y485-L544 HydrophobicContact CE1-CD2 3.79Å; T488-L544 HydrophobicContact CG2-CD2 4.47Å; F516-L544 HydrophobicContact CB-CD1 3.59Å; F516-L544 HydrophobicContact CB-CD2 4.32Å; F516-L544 HydrophobicContact CD1-CD1 4.24Å; F516-L544 HydrophobicContact CD2-CD2 4.08Å; F516-L544 HydrophobicContact CG-CD1 3.85Å; F516-L544 HydrophobicContact CG-CD2 4.21Å; V540-L544 HydrophobicContact CG1-CD1 3.77Å; V540-L544 HydrophobicContact CG1-CG 4.37Å; V540-L544 VanDerWaalsContact O-CG 3.29Å; V540-L544 WeakPolarHBondContact O-CG 3.26Å; V540-L544 PolarHBondContact O-N 3.37Å; L544-Q546 PolarHBondContact O-N 3.38Å; L544-Q546 VanDerWaalsContact O-N 3.12Å; L544-E547 PolarHBondContact O-N 2.8Å
545R97.3Very high97.2Very high186 Ų18648.2 Ų48.270%0.70225%0.254SS*.THydrogen-bonded Turntrans-63.5-10.3171.3-78.1-172-60.3-88.96.4114.3G541 M543G541-R545 WeakPolarHBondContact O-CG 3.25Å; G541-R545 PolarHBondContact O-N 2.89Å; G541-R545 VanDerWaalsContact O-N 3.12Å; G541-R545 PolarHBondContact O-NH1 2.86Å; M543-R545 VanDerWaalsContact C-N 3.29Å; M543-R545 PolarHBondContact O-N 3.39Å
546Q97.3Very high97.3Very high55 Ų5546.2 Ų46.226%0.25724%0.243SC..THydrogen-bonded Turntrans-99.814.4176.8-62.6-172.279.800113.6F38 M543 L544 G548 R549 V550F38-Q546 HydrophobicContact CE1-CB 4.03Å; F38-Q546 HydrophobicContact CZ-CB 4.4Å; M543-Q546 WeakPolarHBondContact O-CB 3.38Å; M543-Q546 PolarHBondContact O-N 3.39Å; L544-Q546 PolarHBondContact O-N 3.38Å; L544-Q546 VanDerWaalsContact O-N 3.12Å; Q546-G548 VanDerWaalsContact C-N 3.26Å; Q546-G548 PolarHBondContact O-N 3.27Å; Q546-G548 VanDerWaalsContact O-N 3.13Å; Q546-R549 HydrophobicContact CB-CB 4.49Å; Q546-R549 WeakPolarHBondContact O-CB 3.34Å; Q546-R549 PolarHBondContact O-N 2.87Å; Q546-V550 PolarHBondContact O-N 3.14Å
547E96.9Very high97.5Very high55 Ų5542.9 Ų42.926%0.25723%0.228SC..Hα-helixtrans-45.4-47.2180-176177.1143.500113.1R481 C484 L544 R549 V550 V551R481-E547 WeakPolarHBondContact CA-OE1 3.42Å; R481-E547 HydrophobicContact CB-CG 4.27Å; R481-E547 VanDerWaalsContact CB-OE1 3.25Å; R481-E547 WeakPolarHBondContact CB-OE1 3.29Å; R481-E547 WeakPolarHBondContact CB-OE2 3.22Å; R481-E547 PolarHBondContact N-OE1 3.2Å; C484-E547 HydrophobicContact CB-CB 4.2Å; C484-E547 HydrophobicContact CB-CG 4.05Å; L544-E547 PolarHBondContact O-N 2.8Å; E547-R549 VanDerWaalsContact C-N 3.32Å; E547-R549 PolarHBondContact O-N 3.22Å; E547-V550 WeakPolarHBondContact O-CB 3.31Å; E547-V550 PolarHBondContact O-N 2.75Å; E547-V550 VanDerWaalsContact O-N 3.11Å; E547-V551 HydrophobicContact CG-CG2 4.43Å; E547-V551 WeakPolarHBondContact O-CG2 3.42Å; E547-V551 PolarHBondContact O-N 2.96Å
548G97.1Very high97.6Very high38 Ų3837.8 Ų37.839%0.39220%0.197SC..Hα-helixtrans-57.4-39.9177.500000113.8Q546 V550 V551 V552Q546-G548 VanDerWaalsContact C-N 3.26Å; Q546-G548 PolarHBondContact O-N 3.27Å; Q546-G548 VanDerWaalsContact O-N 3.13Å; G548-V550 PolarHBondContact O-N 2.74Å; G548-V551 PolarHBondContact O-N 3.17Å; G548-V552 VanDerWaalsContact O-CG2 3.28Å; G548-V552 WeakPolarHBondContact O-CG2 3.31Å; G548-V552 PolarHBondContact O-N 2.99Å
549R98.2Very high97.6Very high88 Ų8833.4 Ų33.433%0.33217%0.166SC..Hα-helixtrans-65.6-37.9176.7-64.2-179.6176.6-175-8.5112F37 W43 Q546 E547 V552 Y553F37-R549 HydrophobicContact CZ-CB 3.79Å; W43-R549 HydrophobicContact CD2-CB 4.03Å; W43-R549 HydrophobicContact CD2-CG 4.1Å; W43-R549 HydrophobicContact CE3-CB 3.62Å; W43-R549 HydrophobicContact CE3-CG 4.08Å; W43-R549 HydrophobicContact CH2-CB 4.22Å; W43-R549 HydrophobicContact CH2-CG 4Å; W43-R549 HydrophobicContact CZ2-CG 4.05Å; W43-R549 HydrophobicContact CZ3-CB 3.72Å; W43-R549 HydrophobicContact CZ3-CG 4.02Å; Q546-R549 HydrophobicContact CB-CB 4.49Å; Q546-R549 WeakPolarHBondContact O-CB 3.34Å; Q546-R549 PolarHBondContact O-N 2.87Å; E547-R549 VanDerWaalsContact C-N 3.32Å; E547-R549 PolarHBondContact O-N 3.22Å; R549-V552 PolarHBondContact O-N 3.44Å; R549-Y553 WeakPolarHBondContact O-CB 3.49Å; R549-Y553 PolarHBondContact O-N 3.09Å
550V98.2Very high97.7Very high0 Ų028.2 Ų28.20%015%0.147CC..Hα-helixtrans-65.4-43.2174.9-169.70000110.7I34 F37 F38 H483 C484 Q546 E547 G548 Y553 F554I34-V550 HydrophobicContact CG2-CG1 3.78Å; F37-V550 HydrophobicContact CD1-CG2 3.69Å; F37-V550 HydrophobicContact CD2-CG2 4.38Å; F37-V550 HydrophobicContact CE1-CG2 3.74Å; F37-V550 HydrophobicContact CE2-CG2 4.42Å; F37-V550 HydrophobicContact CG-CG1 4.44Å; F37-V550 HydrophobicContact CG-CG2 4.03Å; F37-V550 HydrophobicContact CZ-CG2 4.11Å; F38-V550 HydrophobicContact CE2-CG2 4.43Å; F38-V550 HydrophobicContact CZ-CG2 3.93Å; H483-V550 HydrophobicContact CB-CG1 3.83Å; C484-V550 HydrophobicContact CB-CB 4.35Å; C484-V550 HydrophobicContact CB-CG2 4.09Å; Q546-V550 PolarHBondContact O-N 3.14Å; E547-V550 WeakPolarHBondContact O-CB 3.31Å; E547-V550 PolarHBondContact O-N 2.75Å; E547-V550 VanDerWaalsContact O-N 3.11Å; G548-V550 PolarHBondContact O-N 2.74Å; V550-Y553 PolarHBondContact O-N 3.47Å; V550-F554 WeakPolarHBondContact O-CB 3.29Å; V550-F554 PolarHBondContact O-N 2.7Å
551V97.9Very high97.6Very high4 Ų427.8 Ų27.82%0.02415%0.145CC..Hα-helixtrans-62-45176.7170.10000111.2I62 L473 L480 E547 G548 S555I62-V551 HydrophobicContact CD1-CG1 3.73Å; L473-V551 HydrophobicContact CD2-CG1 3.59Å; L480-V551 HydrophobicContact CB-CG2 4.06Å; L480-V551 HydrophobicContact CD2-CG1 4.46Å; E547-V551 HydrophobicContact CG-CG2 4.43Å; E547-V551 WeakPolarHBondContact O-CG2 3.42Å; E547-V551 PolarHBondContact O-N 2.96Å; G548-V551 PolarHBondContact O-N 3.17Å; V551-S555 WeakPolarHBondContact O-CB 3.28Å; V551-S555 PolarHBondContact O-N 3.24Å; V551-S555 PolarHBondContact O-OG 3.45Å
552V98.1Very high97.6Very high1 Ų127.6 Ų27.61%0.00614%0.141CC..Hα-helixtrans-66.1-44.8176.2178.50000111.8W43 L54 I62 G548 R549 F554 S555 L556W43-V552 HydrophobicContact CZ3-CB 4.33Å; W43-V552 HydrophobicContact CZ3-CG1 4.45Å; L54-V552 HydrophobicContact CB-CG1 3.91Å; L54-V552 HydrophobicContact CD1-CG1 4.01Å; L54-V552 HydrophobicContact CD2-CG1 3.97Å; L54-V552 HydrophobicContact CG-CG1 4.18Å; I62-V552 HydrophobicContact CD1-CB 4.4Å; I62-V552 HydrophobicContact CD1-CG2 3.32Å; I62-V552 HydrophobicContact CG1-CG2 3.84Å; G548-V552 VanDerWaalsContact O-CG2 3.28Å; G548-V552 WeakPolarHBondContact O-CG2 3.31Å; G548-V552 PolarHBondContact O-N 2.99Å; R549-V552 PolarHBondContact O-N 3.44Å; V552-F554 PolarHBondContact O-N 3.18Å; V552-S555 WeakPolarHBondContact O-CA 3.42Å; V552-S555 VanDerWaalsContact O-CB 3.29Å; V552-S555 WeakPolarHBondContact O-CB 3.42Å; V552-S555 PolarHBondContact O-N 2.73Å; V552-L556 PolarHBondContact O-N 2.8Å
553Y98.5Very high97.6Very high0 Ų025.8 Ų25.80%013%0.126CC..Hα-helixtrans-64.6-41.7-179.8-165.9-79000111.8H28 S32 I34 F37 L42 T45 L46 R549 V550 S555 L556 A557H28-Y553 PolarHBondContact O-OH 2.94Å; S32-Y553 PolarHBondContact OG-OH 3.29Å; I34-Y553 HydrophobicContact CD1-CD1 3.8Å; I34-Y553 HydrophobicContact CD1-CE1 4.29Å; F37-Y553 HydrophobicContact CD2-CG 4.24Å; F37-Y553 HydrophobicContact CE2-CD2 4.4Å; F37-Y553 HydrophobicContact CE2-CG 4.08Å; L42-Y553 HydrophobicContact CB-CD1 4.49Å; L42-Y553 HydrophobicContact CB-CD2 4.41Å; L42-Y553 HydrophobicContact CB-CE1 4.08Å; L42-Y553 HydrophobicContact CB-CE2 4.01Å; L42-Y553 HydrophobicContact CD1-CD1 4.5Å; L42-Y553 HydrophobicContact CD1-CE1 3.99Å; L42-Y553 WeakPolarHBondContact O-CE2 3.44Å; T45-Y553 PolarHBondContact OG1-OH 2.86Å; L46-Y553 HydrophobicContact CD1-CD2 3.85Å; L46-Y553 HydrophobicContact CD1-CE2 4.27Å; L46-Y553 HydrophobicContact CD2-CD2 4.03Å; L46-Y553 HydrophobicContact CD2-CE2 3.65Å; L46-Y553 HydrophobicContact CG-CD2 3.9Å; L46-Y553 HydrophobicContact CG-CE2 3.8Å; R549-Y553 WeakPolarHBondContact O-CB 3.49Å; R549-Y553 PolarHBondContact O-N 3.09Å; V550-Y553 PolarHBondContact O-N 3.47Å; Y553-S555 VanDerWaalsContact C-N 3.27Å; Y553-S555 PolarHBondContact O-N 3.01Å; Y553-L556 PolarHBondContact O-N 3.5Å; Y553-A557 PolarHBondContact O-N 2.92Å; Y553-A557 VanDerWaalsContact O-N 3.12Å
554F97.9Very high97.6Very high16 Ų1625.2 Ų25.27%0.0712%0.123CC..Hα-helixtrans-62.2-35.8171.5178.4-128.7000112I34 Y469 H483 V550 V552 L556 A557 L558I34-F554 HydrophobicContact CD1-CB 3.98Å; I34-F554 HydrophobicContact CD1-CD2 4.08Å; I34-F554 HydrophobicContact CD1-CG 4.49Å; I34-F554 HydrophobicContact CG1-CB 4.16Å; I34-F554 HydrophobicContact CG1-CD2 3.71Å; I34-F554 HydrophobicContact CG1-CG 4.27Å; I34-F554 HydrophobicContact CG2-CB 4.32Å; Y469-F554 AromaticContact CD2-CE1 3.94Å; Y469-F554 HydrophobicContact CD2-CE1 3.94Å; Y469-F554 HydrophobicContact CE1-CD1 4.15Å; Y469-F554 HydrophobicContact CE1-CE1 4.35Å; Y469-F554 AromaticContact CE2-CD1 3.79Å; Y469-F554 HydrophobicContact CE2-CD1 3.79Å; Y469-F554 AromaticContact CE2-CE1 3.62Å; Y469-F554 HydrophobicContact CE2-CE1 3.62Å; Y469-F554 HydrophobicContact CG-CE1 4.45Å; Y469-F554 AromaticContact CZ-CD1 3.58Å; Y469-F554 AromaticContact CZ-CE1 3.85Å; H483-F554 AromaticContact CD2-CD1 3.91Å; H483-F554 AromaticContact CE1-CD1 3.68Å; H483-F554 AromaticContact CE1-CE1 3.47Å; H483-F554 VanDerWaalsContact CE1-CE1 3.47Å; H483-F554 WeakPolarHBondContact CE1-CE1 3.2Å; H483-F554 AromaticContact CE1-CZ 3.79Å; H483-F554 AromaticContact NE2-CD1 3.54Å; H483-F554 AromaticContact NE2-CE1 3.36Å; H483-F554 WeakPolarHBondContact NE2-CE1 3.23Å; V550-F554 WeakPolarHBondContact O-CB 3.29Å; V550-F554 PolarHBondContact O-N 2.7Å; V552-F554 PolarHBondContact O-N 3.18Å; F554-L556 PolarHBondContact O-N 3.43Å; F554-A557 PolarHBondContact O-N 2.71Å; F554-L558 HydrophobicContact CE1-CD2 4.45Å; F554-L558 HydrophobicContact CZ-CD1 4.23Å; F554-L558 HydrophobicContact CZ-CD2 4.48Å; F554-L558 VanDerWaalsContact O-CB 3.22Å; F554-L558 WeakPolarHBondContact O-CB 3.12Å; F554-L558 PolarHBondContact O-N 3.05Å
555S98.1Very high97.5Very high0 Ų023.4 Ų23.40%011%0.114CC..Hα-helixtrans-63.7-39174.8-570000112.7I62 L67 Y469 V551 V552 Y553 L558 L559I62-S555 WeakPolarHBondContact CG2-OG 3.4Å; L67-S555 WeakPolarHBondContact CD2-O 3.24Å; Y469-S555 WeakPolarHBondContact CE1-OG 3.46Å; V551-S555 WeakPolarHBondContact O-CB 3.28Å; V551-S555 PolarHBondContact O-N 3.24Å; V551-S555 PolarHBondContact O-OG 3.45Å; V552-S555 WeakPolarHBondContact O-CA 3.42Å; V552-S555 VanDerWaalsContact O-CB 3.29Å; V552-S555 WeakPolarHBondContact O-CB 3.42Å; V552-S555 PolarHBondContact O-N 2.73Å; Y553-S555 VanDerWaalsContact C-N 3.27Å; Y553-S555 PolarHBondContact O-N 3.01Å; S555-L558 PolarHBondContact O-N 3.05Å; S555-L559 WeakPolarHBondContact O-CB 3.35Å; S555-L559 PolarHBondContact O-N 3.12Å
556L98.3Very high97.6Very high0 Ų014.7 Ų14.70%08%0.081CC..Hα-helixtrans-62.9-43.7173.2-66.6171.2000111.8I29 L46 W50 L54 L66 L84 F87 V552 Y553 F554 L559I29-L556 HydrophobicContact CG2-CB 3.91Å; L46-L556 HydrophobicContact CD1-CD1 3.65Å; L46-L556 HydrophobicContact CD2-CD1 3.69Å; L46-L556 HydrophobicContact CG-CD1 4.35Å; W50-L556 HydrophobicContact CE3-CD1 4.47Å; W50-L556 HydrophobicContact CZ3-CD2 4.38Å; L54-L556 HydrophobicContact CD1-CD1 3.94Å; L54-L556 HydrophobicContact CD1-CD2 4.45Å; L66-L556 HydrophobicContact CD1-CD2 3.99Å; L66-L556 HydrophobicContact CD2-CD2 3.88Å; L66-L556 HydrophobicContact CD2-CG 4.27Å; L84-L556 HydrophobicContact CD1-CD2 4.27Å; F87-L556 HydrophobicContact CD1-CD2 4.33Å; F87-L556 HydrophobicContact CE1-CD2 3.65Å; F87-L556 HydrophobicContact CZ-CD2 4.43Å; V552-L556 PolarHBondContact O-N 2.8Å; Y553-L556 PolarHBondContact O-N 3.5Å; F554-L556 PolarHBondContact O-N 3.43Å; L556-L559 PolarHBondContact O-N 2.95Å
557A97.8Very high97.6Very high18 Ų1812.1 Ų12.115%0.1497%0.069CC..Hα-helixtrans-66.6-39.317600000112.3I29 I34 Y553 F554 L559 L560 A561I29-A557 HydrophobicContact CG2-CB 4.05Å; I34-A557 HydrophobicContact CD1-CB 4.49Å; Y553-A557 PolarHBondContact O-N 2.92Å; Y553-A557 VanDerWaalsContact O-N 3.12Å; F554-A557 PolarHBondContact O-N 2.71Å; A557-L559 VanDerWaalsContact C-N 3.3Å; A557-L559 PolarHBondContact O-N 3.26Å; A557-L560 WeakPolarHBondContact O-CB 3.5Å; A557-L560 PolarHBondContact O-N 3.12Å; A557-L560 VanDerWaalsContact O-N 3.13Å; A557-A561 PolarHBondContact O-N 3.06Å
558L96.3Very high97.7Very high4 Ų49.5 Ų9.52%0.0216%0.057CC..Hα-helixtrans-67.7-30.4177.9-168.966.8000112.1H464 I466 Y469 F554 S555 L560 A561H464-L558 HydrophobicContact CB-CD1 3.4Å; I466-L558 HydrophobicContact CG1-CD2 4.28Å; I466-L558 HydrophobicContact CG1-CG 3.86Å; Y469-L558 HydrophobicContact CD1-CD2 3.41Å; Y469-L558 VanDerWaalsContact CD1-CD2 3.41Å; Y469-L558 HydrophobicContact CE1-CD2 4.22Å; Y469-L558 HydrophobicContact CG-CD2 3.62Å; F554-L558 HydrophobicContact CE1-CD2 4.45Å; F554-L558 HydrophobicContact CZ-CD1 4.23Å; F554-L558 HydrophobicContact CZ-CD2 4.48Å; F554-L558 VanDerWaalsContact O-CB 3.22Å; F554-L558 WeakPolarHBondContact O-CB 3.12Å; F554-L558 PolarHBondContact O-N 3.05Å; S555-L558 PolarHBondContact O-N 3.05Å; L558-L560 PolarHBondContact O-N 2.81Å; L558-A561 HydrophobicContact CD1-CB 4.42Å; L558-A561 VanDerWaalsContact O-CB 3.29Å; L558-A561 WeakPolarHBondContact O-CB 3.49Å; L558-A561 PolarHBondContact O-N 3.2Å; L558-A561 VanDerWaalsContact O-N 3.15Å
559L96.7Very high97.7Very high2 Ų27.8 Ų7.81%0.014%0.039CC..Hα-helixtrans-65.3-25.5172.9-16963.3000112.7L66 L67 F87 R88 A91 H92 S555 L556 A557L66-L559 HydrophobicContact CD1-CD2 4.25Å; L67-L559 HydrophobicContact CD2-CB 4.14Å; L67-L559 HydrophobicContact CD2-CD1 4.22Å; F87-L559 HydrophobicContact CD1-CD2 4.34Å; F87-L559 HydrophobicContact CE1-CD2 3.86Å; R88-L559 HydrophobicContact CB-CD2 4.28Å; R88-L559 HydrophobicContact CG-CD2 4.09Å; A91-L559 HydrophobicContact CB-CD2 4.26Å; A91-L559 HydrophobicContact CB-CG 3.89Å; H92-L559 VanDerWaalsContact CE1-CD1 3.47Å; H92-L559 WeakPolarHBondContact CE1-CD1 3.44Å; S555-L559 WeakPolarHBondContact O-CB 3.35Å; S555-L559 PolarHBondContact O-N 3.12Å; L556-L559 PolarHBondContact O-N 2.95Å; A557-L559 VanDerWaalsContact C-N 3.3Å; A557-L559 PolarHBondContact O-N 3.26Å
560L97.8Very high97.7Very high2 Ų23.6 Ų3.61%0.012%0.023CC..Hα-helixtrans-83.7-16.6173.3-64.4177.6000113.6F22 I29 F87 A557 L558 V563 V564F22-L560 HydrophobicContact CD1-CD2 4.25Å; F22-L560 HydrophobicContact CE1-CD2 3.45Å; F22-L560 VanDerWaalsContact CE1-CD2 3.45Å; F22-L560 HydrophobicContact CZ-CD2 4.07Å; I29-L560 HydrophobicContact CB-CD1 3.99Å; I29-L560 HydrophobicContact CG2-CD1 4.2Å; F87-L560 HydrophobicContact CE2-CD1 4.26Å; F87-L560 HydrophobicContact CE2-CD2 3.8Å; F87-L560 HydrophobicContact CE2-CG 4.17Å; F87-L560 HydrophobicContact CZ-CD1 4.39Å; F87-L560 HydrophobicContact CZ-CD2 4.11Å; F87-L560 HydrophobicContact CZ-CG 4.1Å; A557-L560 WeakPolarHBondContact O-CB 3.5Å; A557-L560 PolarHBondContact O-N 3.12Å; A557-L560 VanDerWaalsContact O-N 3.13Å; L558-L560 PolarHBondContact O-N 2.81Å; L560-V563 HydrophobicContact CD2-CG2 4.37Å; L560-V563 VanDerWaalsContact O-CB 3.25Å; L560-V563 WeakPolarHBondContact O-CB 3.3Å; L560-V563 PolarHBondContact O-N 3Å; L560-V564 PolarHBondContact O-N 2.91Å; L560-V564 VanDerWaalsContact O-N 3.12Å
561A96.4Very high97.7Very high5 Ų53.6 Ų3.64%0.0412%0.023CC..Hα-helixtrans-55.7-46.5-177.400000114.1G461 A557 L558 V563 V564 E565G461-A561 WeakPolarHBondContact O-CB 3.38Å; A557-A561 PolarHBondContact O-N 3.06Å; L558-A561 HydrophobicContact CD1-CB 4.42Å; L558-A561 VanDerWaalsContact O-CB 3.29Å; L558-A561 WeakPolarHBondContact O-CB 3.49Å; L558-A561 PolarHBondContact O-N 3.2Å; L558-A561 VanDerWaalsContact O-N 3.15Å; A561-V563 VanDerWaalsContact C-N 3.26Å; A561-V563 PolarHBondContact O-N 2.86Å; A561-V564 PolarHBondContact O-N 2.98Å; A561-E565 PolarHBondContact O-N 2.65Å; A561-E565 VanDerWaalsContact O-N 3.07Å
562P96Very high97.7Very high14 Ų143.5 Ų3.59%0.0912%0.022CC..Hα-helixtrans-73.6-20.1178.8-10.627.3000112.4T95 I466 T566T95-P562 HydrophobicContact CG2-CB 3.87Å; I466-P562 HydrophobicContact CD1-CG 3.49Å; I466-P562 VanDerWaalsContact CD1-CG 3.49Å; I466-P562 HydrophobicContact CG1-CG 4.45Å; P562-T566 VanDerWaalsContact O-CB 3.29Å; P562-T566 WeakPolarHBondContact O-CB 3.42Å; P562-T566 PolarHBondContact O-N 3.42Å; P562-T566 PolarHBondContact O-OG1 2.9Å
563V97.9Very high97.7Very high0 Ų03.9 Ų3.90%02%0.024CC..Hα-helixtrans-68.3-45.2175.3-172.30000109.3L19 F22 L23 A91 T95 L560 A561 T566 L567L19-V563 HydrophobicContact CD2-CG1 3.42Å; L19-V563 VanDerWaalsContact CD2-CG1 3.42Å; F22-V563 HydrophobicContact CD1-CG1 4.03Å; F22-V563 HydrophobicContact CE1-CG1 4.46Å; F22-V563 HydrophobicContact CE1-CG2 4.38Å; L23-V563 HydrophobicContact CD1-CG1 4.23Å; L23-V563 HydrophobicContact CD2-CB 4.12Å; L23-V563 HydrophobicContact CD2-CG1 3.8Å; L23-V563 HydrophobicContact CG-CG1 3.9Å; A91-V563 HydrophobicContact CB-CG2 4.13Å; T95-V563 HydrophobicContact CG2-CB 4.27Å; T95-V563 HydrophobicContact CG2-CG2 3.73Å; L560-V563 HydrophobicContact CD2-CG2 4.37Å; L560-V563 VanDerWaalsContact O-CB 3.25Å; L560-V563 WeakPolarHBondContact O-CB 3.3Å; L560-V563 PolarHBondContact O-N 3Å; A561-V563 VanDerWaalsContact C-N 3.26Å; A561-V563 PolarHBondContact O-N 2.86Å; V563-T566 PolarHBondContact O-N 3.36Å; V563-L567 PolarHBondContact O-N 3.03Å
564V98.3Very high97.6Very high2 Ų24 Ų41%0.0122%0.024CC..Hα-helixtrans-63.4-48.3172.8-1790000110.7L23 L454 A458 A462 L560 A561 T566 L567 V568L23-V564 HydrophobicContact CD1-CG2 4.1Å; L23-V564 HydrophobicContact CD2-CG2 3.72Å; L454-V564 HydrophobicContact CD1-CG1 3.96Å; L454-V564 HydrophobicContact CD2-CG1 4.03Å; A458-V564 HydrophobicContact CB-CG2 4.17Å; A462-V564 HydrophobicContact CB-CB 4.04Å; A462-V564 HydrophobicContact CB-CG1 3.9Å; L560-V564 PolarHBondContact O-N 2.91Å; L560-V564 VanDerWaalsContact O-N 3.12Å; A561-V564 PolarHBondContact O-N 2.98Å; V564-T566 VanDerWaalsContact C-N 3.27Å; V564-T566 PolarHBondContact O-N 3.4Å; V564-L567 PolarHBondContact O-N 3.11Å; V564-L567 VanDerWaalsContact O-N 3.13Å; V564-V568 HydrophobicContact CG1-CG2 4.45Å; V564-V568 VanDerWaalsContact O-CG2 3.27Å; V564-V568 WeakPolarHBondContact O-CG2 3.5Å; V564-V568 PolarHBondContact O-N 2.91Å; V564-V568 VanDerWaalsContact O-N 3.12Å
565E97.6Very high97.6Very high2 Ų24.1 Ų4.11%0.0093%0.025CC..Hα-helixtrans-55-42.6175.2176.2160.5-117.300111.7R98 Y406 A462 A561 V568 L569 R596R98-E565 IonicContact CZ-OE2 3.84Å; R98-E565 IonicContact NH1-OE2 2.71Å; R98-E565 PolarHBondContact NH1-OE2 3.07Å; Y406-E565 HydrophobicContact CE2-CB 4.27Å; Y406-E565 HydrophobicContact CE2-CG 3.95Å; Y406-E565 WeakPolarHBondContact CE2-OE1 3.37Å; Y406-E565 WeakPolarHBondContact OH-CG 3.14Å; Y406-E565 PolarHBondContact OH-OE1 3.3Å; A462-E565 HydrophobicContact CB-CB 4.36Å; A561-E565 PolarHBondContact O-N 2.65Å; A561-E565 VanDerWaalsContact O-N 3.07Å; E565-V568 PolarHBondContact O-N 3.37Å; E565-L569 HydrophobicContact CG-CD1 3.78Å; E565-L569 HydrophobicContact CG-CG 4.48Å; E565-L569 WeakPolarHBondContact O-CB 3.5Å; E565-L569 VanDerWaalsContact O-CG 3.25Å; E565-L569 WeakPolarHBondContact O-CG 3.5Å; E565-L569 PolarHBondContact O-N 3.31Å; E565-R596 IonicContact OE1-NE 3.51Å; E565-R596 IonicContact OE1-NH2 2.7Å; E565-R596 IonicContact OE2-NH2 3.77Å
566T97.6Very high97.6Very high3 Ų34.1 Ų4.12%0.0183%0.025CC..Hα-helixtrans-61.9-45.3176.5-600000111.5L19 L94 T95 F96 P562 V563 V564 V568 L569 L570L19-T566 HydrophobicContact CD1-CG2 3.83Å; L19-T566 HydrophobicContact CD2-CG2 4.33Å; L94-T566 VanDerWaalsContact O-CG2 3.31Å; L94-T566 WeakPolarHBondContact O-CG2 3.17Å; T95-T566 WeakPolarHBondContact CA-OG1 3.39Å; F96-T566 HydrophobicContact CD2-CG2 3.3Å; F96-T566 HydrophobicContact CE2-CG2 3.51Å; F96-T566 HydrophobicContact CG-CG2 3.91Å; F96-T566 HydrophobicContact CZ-CG2 4.28Å; F96-T566 PolarHBondContact N-OG1 2.88Å; P562-T566 VanDerWaalsContact O-CB 3.29Å; P562-T566 WeakPolarHBondContact O-CB 3.42Å; P562-T566 PolarHBondContact O-N 3.42Å; P562-T566 PolarHBondContact O-OG1 2.9Å; V563-T566 PolarHBondContact O-N 3.36Å; V564-T566 VanDerWaalsContact C-N 3.27Å; V564-T566 PolarHBondContact O-N 3.4Å; T566-V568 PolarHBondContact O-N 3.17Å; T566-L569 PolarHBondContact O-N 3.34Å; T566-L570 VanDerWaalsContact O-CB 3.22Å; T566-L570 WeakPolarHBondContact O-CB 3.29Å; T566-L570 PolarHBondContact O-N 3Å
567L98.6Very high97.4Very high0 Ų06.7 Ų6.70%04%0.037CC..Hα-helixtrans-62.3-44.6179.1-179.157.1000112.3L19 T20 L23 Y440 V446 L454 V563 V564 L569 L570 D571L19-L567 HydrophobicContact CB-CB 4.34Å; L19-L567 HydrophobicContact CB-CD1 4.08Å; L19-L567 HydrophobicContact CD1-CB 4.17Å; L19-L567 HydrophobicContact CD1-CD1 4.27Å; T20-L567 HydrophobicContact CG2-CD1 4.16Å; T20-L567 HydrophobicContact CG2-CD2 3.95Å; L23-L567 HydrophobicContact CD1-CB 4.42Å; L23-L567 HydrophobicContact CD1-CD2 3.83Å; Y440-L567 WeakPolarHBondContact OH-CD2 3.43Å; V446-L567 HydrophobicContact CG1-CD1 4.26Å; V446-L567 HydrophobicContact CG2-CD1 4.49Å; L454-L567 HydrophobicContact CD1-CD2 4.37Å; L454-L567 HydrophobicContact CD2-CD2 4.25Å; L454-L567 HydrophobicContact CG-CD2 4.49Å; V563-L567 PolarHBondContact O-N 3.03Å; V564-L567 PolarHBondContact O-N 3.11Å; V564-L567 VanDerWaalsContact O-N 3.13Å; L567-L569 VanDerWaalsContact C-N 3.3Å; L567-L569 PolarHBondContact O-N 2.95Å; L567-L570 PolarHBondContact O-N 3.27Å; L567-D571 WeakPolarHBondContact O-CB 3.4Å; L567-D571 PolarHBondContact O-N 3.41Å
568V98.3Very high97.3Very high0 Ų09.1 Ų9.10%05%0.045CC..Hα-helixtrans-69.9-27.8178.5-154.20000111.7Y406 I409 Y440 L454 V564 E565 T566 R572Y406-V568 HydrophobicContact CD1-CB 4.39Å; Y406-V568 HydrophobicContact CD1-CG1 4.42Å; I409-V568 HydrophobicContact CD1-CG1 3.94Å; Y440-V568 HydrophobicContact CD2-CB 4.43Å; Y440-V568 HydrophobicContact CD2-CG1 3.72Å; Y440-V568 HydrophobicContact CE2-CG1 4.38Å; Y440-V568 HydrophobicContact CG-CG1 4.31Å; L454-V568 HydrophobicContact CD1-CG2 3.58Å; V564-V568 HydrophobicContact CG1-CG2 4.45Å; V564-V568 VanDerWaalsContact O-CG2 3.27Å; V564-V568 WeakPolarHBondContact O-CG2 3.5Å; V564-V568 PolarHBondContact O-N 2.91Å; V564-V568 VanDerWaalsContact O-N 3.12Å; E565-V568 PolarHBondContact O-N 3.37Å; T566-V568 PolarHBondContact O-N 3.17Å; V568-R572 VanDerWaalsContact CG1-NH1 3.32Å; V568-R572 WeakPolarHBondContact O-CD 3.23Å; V568-R572 WeakPolarHBondContact O-CG 3.37Å; V568-R572 PolarHBondContact O-NH1 2.89Å
569L97.8Very high97.3Very high3 Ų314.4 Ų14.42%0.0167%0.067CC..Hα-helixtrans-77.5-36.6174.6-70.3171000112.2F96 E565 T566 L567 R572 M573 L585 L598F96-L569 HydrophobicContact CD2-CB 4.47Å; F96-L569 HydrophobicContact CE2-CB 4.27Å; E565-L569 HydrophobicContact CG-CD1 3.78Å; E565-L569 HydrophobicContact CG-CG 4.48Å; E565-L569 WeakPolarHBondContact O-CB 3.5Å; E565-L569 VanDerWaalsContact O-CG 3.25Å; E565-L569 WeakPolarHBondContact O-CG 3.5Å; E565-L569 PolarHBondContact O-N 3.31Å; T566-L569 PolarHBondContact O-N 3.34Å; L567-L569 VanDerWaalsContact C-N 3.3Å; L567-L569 PolarHBondContact O-N 2.95Å; L569-R572 PolarHBondContact O-N 2.73Å; L569-M573 PolarHBondContact O-N 3.46Å; L569-M573 VanDerWaalsContact O-N 3.16Å; L569-L585 HydrophobicContact CB-CD1 3.81Å; L569-L585 HydrophobicContact CB-CD2 4.15Å; L569-L585 HydrophobicContact CD1-CD2 4.34Å; L569-L585 HydrophobicContact CD2-CD2 4.01Å; L569-L585 HydrophobicContact CG-CD2 4.4Å; L569-L598 HydrophobicContact CD1-CB 3.9Å; L569-L598 HydrophobicContact CD1-CD1 3.56Å; L569-L598 HydrophobicContact CD1-CG 4.38Å
570L97.9Very high97.1Very high0 Ų017.5 Ų17.50%010%0.1CC..Hα-helixtrans-69.5-39.4177.1178.861000112.4Q12 L15 A16 L19 F96 T566 L567 R572 M573 L574Q12-L570 HydrophobicContact CB-CD1 3.84Å; Q12-L570 HydrophobicContact CG-CD1 4.01Å; L15-L570 HydrophobicContact CB-CD2 3.93Å; L15-L570 HydrophobicContact CD2-CD2 3.99Å; L15-L570 HydrophobicContact CG-CD2 3.77Å; A16-L570 HydrophobicContact CB-CD2 3.71Å; A16-L570 HydrophobicContact CB-CG 4.39Å; L19-L570 HydrophobicContact CD1-CD2 3.68Å; F96-L570 HydrophobicContact CE2-CB 4.02Å; F96-L570 HydrophobicContact CZ-CB 4.13Å; F96-L570 HydrophobicContact CZ-CD1 4.13Å; T566-L570 VanDerWaalsContact O-CB 3.22Å; T566-L570 WeakPolarHBondContact O-CB 3.29Å; T566-L570 PolarHBondContact O-N 3Å; L567-L570 PolarHBondContact O-N 3.27Å; L570-R572 VanDerWaalsContact C-N 3.28Å; L570-R572 PolarHBondContact O-N 3.02Å; L570-M573 WeakPolarHBondContact O-CB 3.27Å; L570-M573 PolarHBondContact O-N 3.34Å; L570-M573 VanDerWaalsContact O-N 3.12Å; L570-L574 HydrophobicContact CD1-CD1 4.38Å; L570-L574 HydrophobicContact CD1-CG 4.33Å; L570-L574 HydrophobicContact CG-CD1 4.09Å; L570-L574 HydrophobicContact CG-CG 4.49Å; L570-L574 WeakPolarHBondContact O-CB 3.43Å; L570-L574 WeakPolarHBondContact O-CG 3.35Å; L570-L574 PolarHBondContact O-N 3.48Å
571D98.4Very high96.9Very high0 Ų018.5 Ų18.50%011%0.105CC..Hα-helixtrans-53.4-44.9171.217256.2000111.9Y440 M442 S443 V446 L567 L574 Y575Y440-D571 HydrophobicContact CD2-CB 4.19Å; Y440-D571 WeakPolarHBondContact CD2-OD2 3.48Å; Y440-D571 HydrophobicContact CE2-CB 3.96Å; M442-D571 VanDerWaalsContact N-CG 3.34Å; M442-D571 PolarHBondContact N-OD1 3.22Å; M442-D571 VanDerWaalsContact N-OD1 3.13Å; M442-D571 PolarHBondContact N-OD2 3.28Å; S443-D571 WeakPolarHBondContact CB-O 3.32Å; S443-D571 WeakPolarHBondContact CB-OD1 3.26Å; S443-D571 PolarHBondContact N-OD1 2.88Å; S443-D571 PolarHBondContact OG-OD1 3.24Å; V446-D571 HydrophobicContact CB-CB 4.42Å; V446-D571 HydrophobicContact CG2-CB 4.06Å; L567-D571 WeakPolarHBondContact O-CB 3.4Å; L567-D571 PolarHBondContact O-N 3.41Å; D571-L574 PolarHBondContact O-N 3.08Å; D571-Y575 WeakPolarHBondContact O-CB 3.45Å; D571-Y575 PolarHBondContact O-N 3.34Å
572R97.8Very high96.7Very high2 Ų226.8 Ų26.81%0.00814%0.14CC..Hα-helixtrans-66-37175.6-64.7169.9-178.7115.3-13.4113S383 L387 M442 V568 L569 L570 L576 L600S383-R572 PolarHBondContact OG-NH2 3.47Å; L387-R572 HydrophobicContact CD1-CB 3.66Å; L387-R572 HydrophobicContact CD1-CG 3.57Å; M442-R572 HydrophobicContact SD-CG 4.2Å; V568-R572 VanDerWaalsContact CG1-NH1 3.32Å; V568-R572 WeakPolarHBondContact O-CD 3.23Å; V568-R572 WeakPolarHBondContact O-CG 3.37Å; V568-R572 PolarHBondContact O-NH1 2.89Å; L569-R572 PolarHBondContact O-N 2.73Å; L570-R572 VanDerWaalsContact C-N 3.28Å; L570-R572 PolarHBondContact O-N 3.02Å; R572-L576 PolarHBondContact O-N 3.44Å; R572-L600 HydrophobicContact CB-CD1 3.63Å
573M97.5Very high96.6Very high8 Ų826.8 Ų26.84%0.03914%0.141CC..Hα-helixtrans-65.4-44.4173.9-70-174.766.600111.6F96 L569 L570 L576 Q577 S583 L585F96-M573 HydrophobicContact CZ-SD 4.05Å; L569-M573 PolarHBondContact O-N 3.46Å; L569-M573 VanDerWaalsContact O-N 3.16Å; L570-M573 WeakPolarHBondContact O-CB 3.27Å; L570-M573 PolarHBondContact O-N 3.34Å; L570-M573 VanDerWaalsContact O-N 3.12Å; M573-L576 PolarHBondContact O-N 3.17Å; M573-Q577 WeakPolarHBondContact O-CB 3.17Å; M573-Q577 PolarHBondContact O-N 3.08Å; M573-S583 WeakPolarHBondContact CA-OG 3.47Å; M573-L585 HydrophobicContact CG-CD1 4.35Å; M573-L585 HydrophobicContact CG-CG 4.32Å; M573-L585 HydrophobicContact SD-CD1 3.52Å; M573-L585 VanDerWaalsContact SD-CD1 3.52Å; M573-L585 HydrophobicContact SD-CG 3.69Å
574L97.6Very high96.4Very high3 Ų328.5 Ų28.52%0.01615%0.149CC..Hα-helixtrans-63.9-41.8177.3-73.9169.6000111.5Q12 R13 A16 W445 V446 L570 D571 L576 Q577 E578Q12-L574 HydrophobicContact CB-CD2 3.81Å; Q12-L574 HydrophobicContact CB-CG 4.45Å; R13-L574 HydrophobicContact CG-CD2 4.07Å; A16-L574 HydrophobicContact CB-CD1 4.01Å; W445-L574 HydrophobicContact CB-CD1 4.45Å; W445-L574 HydrophobicContact CG-CD1 4.4Å; V446-L574 HydrophobicContact CG2-CD1 3.82Å; L570-L574 HydrophobicContact CD1-CD1 4.38Å; L570-L574 HydrophobicContact CD1-CG 4.33Å; L570-L574 HydrophobicContact CG-CD1 4.09Å; L570-L574 HydrophobicContact CG-CG 4.49Å; L570-L574 WeakPolarHBondContact O-CB 3.43Å; L570-L574 WeakPolarHBondContact O-CG 3.35Å; L570-L574 PolarHBondContact O-N 3.48Å; D571-L574 PolarHBondContact O-N 3.08Å; L574-L576 VanDerWaalsContact C-N 3.35Å; L574-L576 PolarHBondContact O-N 3.25Å; L574-Q577 CarbonylContact O-C 3.54Å; L574-Q577 WeakPolarHBondContact O-CB 3.47Å; L574-Q577 PolarHBondContact O-N 3.13Å; L574-Q577 VanDerWaalsContact O-N 3.15Å; L574-E578 VanDerWaalsContact O-CG 3.29Å; L574-E578 WeakPolarHBondContact O-CG 3.21Å; L574-E578 PolarHBondContact O-N 3.43Å
575Y97.7Very high96.2Very high19 Ų1929.3 Ų29.38%0.07515%0.153CC..Hα-helixtrans-56.8-45.8174.2169.5-101.1000111.9L387 V391 M442 D571 E578 K579L387-Y575 HydrophobicContact CB-CD1 4.37Å; L387-Y575 HydrophobicContact CB-CE1 4.09Å; V391-Y575 HydrophobicContact CG2-CE1 3.71Å; M442-Y575 HydrophobicContact CB-CD2 3.94Å; M442-Y575 HydrophobicContact CB-CG 3.89Å; M442-Y575 HydrophobicContact CE-CD1 3.85Å; M442-Y575 HydrophobicContact CE-CD2 4.31Å; M442-Y575 HydrophobicContact CE-CE1 3.67Å; M442-Y575 HydrophobicContact CE-CE2 4.12Å; M442-Y575 HydrophobicContact CE-CG 4.16Å; M442-Y575 VanDerWaalsContact O-CD2 3.27Å; M442-Y575 WeakPolarHBondContact O-CD2 3.47Å; D571-Y575 WeakPolarHBondContact O-CB 3.45Å; D571-Y575 PolarHBondContact O-N 3.34Å; Y575-E578 PolarHBondContact O-N 3.09Å; Y575-K579 WeakPolarHBondContact O-CG 3.27Å; Y575-K579 PolarHBondContact O-N 3.38Å
576L96.8Very high96Very high0 Ų030 Ų300%016%0.157CC..Hα-helixtrans-66.3-39.6175.8-68.9-177.4000112.2L387 F390 V391 R572 M573 L574 E578 K579 G580 I581 L600 A602L387-L576 HydrophobicContact CD2-CD1 3.75Å; L387-L576 HydrophobicContact CD2-CD2 3.99Å; L387-L576 HydrophobicContact CD2-CG 4.03Å; F390-L576 HydrophobicContact CD1-CD1 4.49Å; F390-L576 HydrophobicContact CD1-CD2 3.76Å; F390-L576 HydrophobicContact CE1-CD1 4.15Å; F390-L576 HydrophobicContact CE1-CD2 3.84Å; V391-L576 HydrophobicContact CG2-CD2 3.71Å; R572-L576 PolarHBondContact O-N 3.44Å; M573-L576 PolarHBondContact O-N 3.17Å; L574-L576 VanDerWaalsContact C-N 3.35Å; L574-L576 PolarHBondContact O-N 3.25Å; L576-E578 VanDerWaalsContact C-N 3.34Å; L576-E578 PolarHBondContact O-N 3.27Å; L576-K579 CarbonylContact O-C 3.57Å; L576-K579 WeakPolarHBondContact O-CA 3.29Å; L576-K579 PolarHBondContact O-N 2.93Å; L576-G580 PolarHBondContact O-N 2.85Å; L576-I581 CarbonylContact C-O 3.54Å; L576-I581 VanDerWaalsContact C-O 3.28Å; L576-I581 HydrophobicContact CB-CB 4.26Å; L576-I581 HydrophobicContact CD2-CD1 4.49Å; L576-I581 PolarHBondContact O-N 2.74Å; L576-L600 HydrophobicContact CD1-CD2 3.95Å; L576-A602 HydrophobicContact CD1-CB 3.74Å
577Q95Very high95.8Very high54 Ų5430.7 Ų30.725%0.25216%0.162SC..Hα-helixtrans-64-36.8176.8-172.5-178.5-101.100112.4A9 M573 L574 K579 G580 I581A9-Q577 VanDerWaalsContact CA-OE1 3.24Å; A9-Q577 VanDerWaalsContact CB-OE1 3.31Å; M573-Q577 WeakPolarHBondContact O-CB 3.17Å; M573-Q577 PolarHBondContact O-N 3.08Å; L574-Q577 CarbonylContact O-C 3.54Å; L574-Q577 WeakPolarHBondContact O-CB 3.47Å; L574-Q577 PolarHBondContact O-N 3.13Å; L574-Q577 VanDerWaalsContact O-N 3.15Å; Q577-K579 PolarHBondContact O-N 3.11Å; Q577-G580 PolarHBondContact O-N 3.27Å; Q577-I581 PolarHBondContact N-O 2.85Å
578E95.6Very high95.5Very high68 Ų6832.3 Ų32.332%0.31817%0.17SC..Hα-helixtrans-63.6-18.6171.9-72.9170.3172.200112.8S443 S444 W445 L574 Y575 L576S443-E578 WeakPolarHBondContact CA-OE2 2.83Å; S444-E578 WeakPolarHBondContact CA-OE1 3.44Å; S444-E578 PolarHBondContact N-OE1 3.33Å; S444-E578 PolarHBondContact N-OE2 3.44Å; S444-E578 PolarHBondContact OG-OE1 3.06Å; S444-E578 PolarHBondContact OG-OE2 3.15Å; W445-E578 PolarHBondContact N-OE1 2.85Å; L574-E578 VanDerWaalsContact O-CG 3.29Å; L574-E578 WeakPolarHBondContact O-CG 3.21Å; L574-E578 PolarHBondContact O-N 3.43Å; Y575-E578 PolarHBondContact O-N 3.09Å; L576-E578 VanDerWaalsContact C-N 3.34Å; L576-E578 PolarHBondContact O-N 3.27Å
579K95.3Very high95.2Very high115 Ų11532.3 Ų32.350%0.517%0.17SC..THydrogen-bonded Turntrans-101.113.1171.1-48.2-53.3170.4-1650112.9V391 Y575 L576 Q577 I581V391-K579 HydrophobicContact CG1-CB 4.34Å; V391-K579 HydrophobicContact CG1-CD 4.44Å; V391-K579 HydrophobicContact CG1-CG 3.9Å; V391-K579 HydrophobicContact CG2-CB 4.4Å; V391-K579 HydrophobicContact CG2-CG 4.04Å; Y575-K579 WeakPolarHBondContact O-CG 3.27Å; Y575-K579 PolarHBondContact O-N 3.38Å; L576-K579 CarbonylContact O-C 3.57Å; L576-K579 WeakPolarHBondContact O-CA 3.29Å; L576-K579 PolarHBondContact O-N 2.93Å; Q577-K579 PolarHBondContact O-N 3.11Å; K579-I581 PolarHBondContact O-N 2.95Å
580G93.5Very high94.8Very high68 Ų6833.1 Ų33.170%0.70117%0.174SC*.THydrogen-bonded Turntrans74.73.3-17900000115.1L576 Q577L576-G580 PolarHBondContact O-N 2.85Å; Q577-G580 PolarHBondContact O-N 3.27Å
581I94.1Very high94.3Very high22 Ų2234 Ų3411%0.11318%0.18CC..  trans-90.2123.3-175.9-57.7173.1000109.9F390 V391 L576 Q577 K579 A602F390-I581 HydrophobicContact CE1-CD1 4Å; F390-I581 HydrophobicContact CE1-CG2 3.84Å; F390-I581 HydrophobicContact CZ-CD1 4.3Å; F390-I581 HydrophobicContact CZ-CG2 3.91Å; V391-I581 HydrophobicContact CG2-CD1 4.18Å; L576-I581 CarbonylContact C-O 3.54Å; L576-I581 VanDerWaalsContact C-O 3.28Å; L576-I581 HydrophobicContact CB-CB 4.26Å; L576-I581 HydrophobicContact CD2-CD1 4.49Å; L576-I581 PolarHBondContact O-N 2.74Å; Q577-I581 PolarHBondContact N-O 2.85Å; K579-I581 PolarHBondContact O-N 2.95Å; I581-A602 HydrophobicContact CG2-CB 4Å
582K91.4Very high93.6Very high179 Ų17935 Ų3578%0.77819%0.188SC*.  trans-75.3134.6173.2-65.9-175.3-179.7-178.90110.3
583S94.3Very high93Very high14 Ų1436.2 Ų36.210%0.09819%0.194CC..EExtended strand (participates in β ladder)trans-130.8161.6178.962.10000111.6M573 M601M573-S583 WeakPolarHBondContact CA-OG 3.47Å; S583-M601 CarbonylContact C-O 3.52Å; S583-M601 VanDerWaalsContact CA-O 3.27Å; S583-M601 WeakPolarHBondContact CA-O 3.36Å; S583-M601 WeakPolarHBondContact CB-O 3.48Å
584Q93.3Very high92.6Very high36 Ų3635.8 Ų35.817%0.16819%0.192CC..EExtended strand (participates in β ladder)trans-141.2145177.7-179.9177.2-5.200109.8T6 V586 M601T6-Q584 HydrophobicContact CG2-CB 4.2Å; T6-Q584 HydrophobicContact CG2-CG 4.13Å; Q584-V586 HydrophobicContact CG-CG2 4.19Å; Q584-M601 PolarHBondContact N-O 3.26Å; Q584-M601 PolarHBondContact O-N 3.03Å
585L94.1Very high92.2Very high20 Ų2036.1 Ų36.111%0.10519%0.194CC..EExtended strand (participates in β ladder)trans-97.5130.3163.6-68.9164.7000109.6F96 L569 M573 V599 L600F96-L585 HydrophobicContact CD1-CD1 4.22Å; F96-L585 HydrophobicContact CD2-CD1 3.4Å; F96-L585 VanDerWaalsContact CD2-CD1 3.4Å; F96-L585 HydrophobicContact CE1-CD1 4.06Å; F96-L585 HydrophobicContact CE2-CD1 3.21Å; F96-L585 HydrophobicContact CG-CD1 3.93Å; F96-L585 HydrophobicContact CZ-CD1 3.57Å; L569-L585 HydrophobicContact CB-CD1 3.81Å; L569-L585 HydrophobicContact CB-CD2 4.15Å; L569-L585 HydrophobicContact CD1-CD2 4.34Å; L569-L585 HydrophobicContact CD2-CD2 4.01Å; L569-L585 HydrophobicContact CG-CD2 4.4Å; M573-L585 HydrophobicContact CG-CD1 4.35Å; M573-L585 HydrophobicContact CG-CG 4.32Å; M573-L585 HydrophobicContact SD-CD1 3.52Å; M573-L585 VanDerWaalsContact SD-CD1 3.52Å; M573-L585 HydrophobicContact SD-CG 3.69Å; L585-V599 WeakPolarHBondContact CA-O 3.12Å; L585-L600 HydrophobicContact CD2-CB 3.9Å; L585-L600 HydrophobicContact CD2-CG 4.47Å
586V93.1Very high91.8Very high17 Ų1736.3 Ų36.310%0.10320%0.195CC..EExtended strand (participates in β ladder)trans-115.3117.2179.4-177.70000108.9Q584 L588 L598 V599 M601Q584-V586 HydrophobicContact CG-CG2 4.19Å; V586-L588 VanDerWaalsContact C-N 3.27Å; V586-L588 HydrophobicContact CG1-CB 4.21Å; V586-L588 HydrophobicContact CG1-CD1 4.4Å; V586-L588 PolarHBondContact O-N 2.9Å; V586-L598 WeakPolarHBondContact O-CA 3.24Å; V586-V599 PolarHBondContact N-O 3.45Å; V586-V599 PolarHBondContact O-N 2.85Å; V586-M601 HydrophobicContact CG2-CE 4.13Å
587P93.2Very high91.7Very high16 Ų1636.3 Ų36.310%0.10420%0.195CC..EExtended strand (participates in β ladder)trans-69.987.7166.327.9-31.8000108.6T99 P100 N597 L598T99-P587 VanDerWaalsContact O-CG 3.28Å; T99-P587 WeakPolarHBondContact O-CG 3.24Å; P100-P587 WeakPolarHBondContact CA-O 3.34Å; P100-P587 WeakPolarHBondContact CB-O 3.46Å; P587-N597 CarbonylContact C-O 3.2Å; P587-L598 HydrophobicContact CB-CD2 3.99Å
588L93.2Very high91.6Very high34 Ų3434 Ų3418%0.17818%0.184CC..  trans-92-38.1-168.8-175.465.1000112.4L145 L148 V586 N597 V599L145-L588 HydrophobicContact CB-CD2 4.22Å; L145-L588 HydrophobicContact CD1-CD2 4.07Å; L148-L588 HydrophobicContact CB-CD1 4.44Å; L148-L588 HydrophobicContact CB-CD2 4.17Å; L148-L588 HydrophobicContact CD2-CD1 4.24Å; L148-L588 HydrophobicContact CD2-CD2 3.75Å; V586-L588 VanDerWaalsContact C-N 3.27Å; V586-L588 HydrophobicContact CG1-CB 4.21Å; V586-L588 HydrophobicContact CG1-CD1 4.4Å; V586-L588 PolarHBondContact O-N 2.9Å; L588-N597 PolarHBondContact N-O 3.41Å; L588-V599 HydrophobicContact CB-CB 4.43Å; L588-V599 HydrophobicContact CB-CG2 3.71Å; L588-V599 HydrophobicContact CD2-CB 4.48Å; L588-V599 HydrophobicContact CD2-CG2 3.76Å; L588-V599 HydrophobicContact CG-CG2 4.39Å
589F92.2Very high91.7Very high0 Ų030.8 Ų30.80%017%0.169CC..SBendtrans-94.6159.1179.3-48.1-39.2000110.9H140 E141 L145 L376 V402 P591 R596 N597 V599H140-F589 WeakPolarHBondContact NE2-CA 3.2Å; E141-F589 HydrophobicContact CB-CE1 4.18Å; E141-F589 HydrophobicContact CB-CE2 4.43Å; E141-F589 HydrophobicContact CB-CZ 4.06Å; E141-F589 HydrophobicContact CG-CD1 4.42Å; E141-F589 HydrophobicContact CG-CD2 4.1Å; E141-F589 HydrophobicContact CG-CE1 4.32Å; E141-F589 HydrophobicContact CG-CE2 3.99Å; E141-F589 HydrophobicContact CG-CG 4.33Å; E141-F589 HydrophobicContact CG-CZ 4.11Å; L145-F589 HydrophobicContact CB-CE1 4.21Å; L145-F589 HydrophobicContact CB-CZ 4.25Å; L376-F589 HydrophobicContact CD1-CE2 4.45Å; L376-F589 HydrophobicContact CD1-CZ 4.13Å; V402-F589 HydrophobicContact CG1-CE2 3.9Å; V402-F589 HydrophobicContact CG2-CE2 4.42Å; V402-F589 HydrophobicContact CG2-CZ 4.32Å; F589-P591 WeakPolarHBondContact O-CD 3.48Å; F589-R596 WeakPolarHBondContact CD2-O 3.33Å; F589-N597 HydrophobicContact CB-CB 4.12Å; F589-N597 PolarHBondContact N-O 2.91Å; F589-N597 WeakPolarHBondContact O-CB 3.48Å; F589-N597 PolarHBondContact O-ND2 3.02Å; F589-V599 HydrophobicContact CE2-CG2 4.38Å; F589-V599 HydrophobicContact CZ-CG2 4.28Å
590D88.2Confident91.8Very high20 Ų2025.4 Ų25.411%0.10715%0.146CC..  trans-71.7118.4170.6-161-61.9000110K103 P113 H140 A592 F593 S594K103-D590 IonicContact NZ-OD2 2.99Å; K103-D590 PolarHBondContact NZ-OD2 3.34Å; P113-D590 HydrophobicContact CG-CB 3.84Å; H140-D590 PolarHBondContact NE2-N 2.96Å; D590-A592 PolarHBondContact O-N 2.86Å; D590-A592 PolarHBondContact OD1-N 3.08Å; D590-F593 HydrophobicContact CB-CB 4.36Å; D590-F593 PolarHBondContact O-N 3.27Å; D590-S594 PolarHBondContact O-N 3Å
591P87.4Confident91.9Very high19 Ų1923.4 Ų23.412%0.12312%0.118CC..THydrogen-bonded Turntrans-67.4-19-171.927.9-35.7000113.6R98 E467 F589 F593 P595 N597R98-P591 HydrophobicContact CB-CB 4.37Å; E467-P591 HydrophobicContact CG-CB 4.32Å; F589-P591 WeakPolarHBondContact O-CD 3.48Å; P591-F593 VanDerWaalsContact C-N 3.27Å; P591-F593 PolarHBondContact O-N 3.14Å; P591-P595 WeakPolarHBondContact O-CA 3.49Å; P591-P595 WeakPolarHBondContact O-CG 3.33Å; P591-N597 HydrophobicContact CB-CB 4.16Å
592A83.8Confident92Very high20 Ų2022.5 Ų22.517%0.16511%0.114CC..THydrogen-bonded Turntrans-78.7-8.3172.900000113.3E467 D590E467-A592 HydrophobicContact CB-CB 4.4Å; D590-A592 PolarHBondContact O-N 2.86Å; D590-A592 PolarHBondContact OD1-N 3.08Å
593F85.8Confident92.2Very high28 Ų2816.8 Ų16.812%0.1239%0.092CC..THydrogen-bonded Turntrans-128.2-35.1-173.5-166.1-115000113.4K112 P113 F116 P136 K137 H140 D590 P591K112-F593 HydrophobicContact CD-CE2 4.29Å; K112-F593 HydrophobicContact CG-CD2 4.13Å; K112-F593 HydrophobicContact CG-CE2 4.03Å; P113-F593 HydrophobicContact CG-CB 4.18Å; P113-F593 HydrophobicContact CG-CD1 3.82Å; P113-F593 HydrophobicContact CG-CE1 4.45Å; P113-F593 HydrophobicContact CG-CG 4.15Å; F116-F593 AromaticContact CD2-CE1 3.92Å; F116-F593 HydrophobicContact CD2-CE1 3.92Å; F116-F593 AromaticContact CD2-CZ 3.93Å; F116-F593 HydrophobicContact CD2-CZ 3.93Å; F116-F593 HydrophobicContact CE1-CZ 4.39Å; F116-F593 HydrophobicContact CE2-CD1 4.15Å; F116-F593 AromaticContact CE2-CE1 3.27Å; F116-F593 HydrophobicContact CE2-CE1 3.27Å; F116-F593 AromaticContact CE2-CZ 3.65Å; F116-F593 HydrophobicContact CE2-CZ 3.65Å; F116-F593 HydrophobicContact CG-CZ 4.43Å; F116-F593 AromaticContact CZ-CE1 3.67Å; F116-F593 HydrophobicContact CZ-CE1 3.67Å; F116-F593 AromaticContact CZ-CZ 3.9Å; F116-F593 HydrophobicContact CZ-CZ 3.9Å; P136-F593 HydrophobicContact CB-CZ 3.86Å; K137-F593 HydrophobicContact CB-CE1 4.4Å; K137-F593 WeakPolarHBondContact CD-O 3.22Å; K137-F593 WeakPolarHBondContact CG-O 3.45Å; H140-F593 HydrophobicContact CB-CD1 4.01Å; H140-F593 HydrophobicContact CB-CE1 3.89Å; D590-F593 HydrophobicContact CB-CB 4.36Å; D590-F593 PolarHBondContact O-N 3.27Å; P591-F593 VanDerWaalsContact C-N 3.27Å; P591-F593 PolarHBondContact O-N 3.14Å
594S89.9Confident92.1Very high0 Ų018 Ų180%010%0.096CC..  trans-126.697.7155-168.20000110.7K137 E141 D590 R596 N597K137-S594 WeakPolarHBondContact CE-OG 3.39Å; K137-S594 PolarHBondContact NZ-OG 3.42Å; E141-S594 WeakPolarHBondContact OE1-CB 3.38Å; E141-S594 PolarHBondContact OE1-OG 2.82Å; D590-S594 PolarHBondContact O-N 3Å; S594-R596 PolarHBondContact O-N 3.49Å; S594-R596 VanDerWaalsContact O-N 3.07Å; S594-N597 WeakPolarHBondContact O-CB 3.35Å
595P87.8Confident91.4Very high10 Ų1024 Ų247%0.06512%0.123CC..SBendtrans-66.3-7-179.7-23.533.2000115.7R98 A465 P591 N597R98-P595 PolarHBondContact NH2-O 3.04Å; A465-P595 HydrophobicContact CB-CB 3.53Å; A465-P595 HydrophobicContact CB-CG 3.47Å; A465-P595 VanDerWaalsContact CB-CG 3.47Å; P591-P595 WeakPolarHBondContact O-CA 3.49Å; P591-P595 WeakPolarHBondContact O-CG 3.33Å; P595-N597 VanDerWaalsContact C-N 3.26Å; P595-N597 PolarHBondContact O-N 3.31Å
596R90.9Very high90.1Very high23 Ų2328 Ų289%0.08715%0.15CC..  trans-92.662.5169.3-8555.3-92.3177.6-1.3107.9C404 A462 C463 H464 E565 F589 S594C404-R596 HydrophobicContact CB-CB 4.42Å; C404-R596 HydrophobicContact CB-CG 3.73Å; A462-R596 PolarHBondContact O-NH2 2.94Å; C463-R596 VanDerWaalsContact C-NH1 3.28Å; C463-R596 PolarHBondContact O-NH1 2.84Å; H464-R596 PolarHBondContact O-NH1 3.17Å; H464-R596 PolarHBondContact O-NH2 3.17Å; E565-R596 IonicContact OE1-NE 3.51Å; E565-R596 IonicContact OE1-NH2 2.7Å; E565-R596 IonicContact OE2-NH2 3.77Å; F589-R596 WeakPolarHBondContact CD2-O 3.33Å; S594-R596 PolarHBondContact O-N 3.49Å; S594-R596 VanDerWaalsContact O-N 3.07Å
597N92.8Very high88.3Confident0 Ų032.1 Ų32.10%018%0.176CC..  trans-94.8-13.3-156.8104.4-71.2000114.5R98 P587 L588 F589 P591 S594 P595R98-N597 PolarHBondContact O-ND2 3.22Å; P587-N597 CarbonylContact C-O 3.2Å; L588-N597 PolarHBondContact N-O 3.41Å; F589-N597 HydrophobicContact CB-CB 4.12Å; F589-N597 PolarHBondContact N-O 2.91Å; F589-N597 WeakPolarHBondContact O-CB 3.48Å; F589-N597 PolarHBondContact O-ND2 3.02Å; P591-N597 HydrophobicContact CB-CB 4.16Å; S594-N597 WeakPolarHBondContact O-CB 3.35Å; P595-N597 VanDerWaalsContact C-N 3.26Å; P595-N597 PolarHBondContact O-N 3.31Å
598L94.4Very high86Confident6 Ų642.6 Ų42.63%0.03121%0.213CC..EExtended strand (participates in β ladder)trans-87.1126.7178.1-65.1170.3000110.8F96 L569 V586 P587F96-L598 HydrophobicContact CB-CD1 3.88Å; L569-L598 HydrophobicContact CD1-CB 3.9Å; L569-L598 HydrophobicContact CD1-CD1 3.56Å; L569-L598 HydrophobicContact CD1-CG 4.38Å; V586-L598 WeakPolarHBondContact O-CA 3.24Å; P587-L598 HydrophobicContact CB-CD2 3.99Å
599V96.5Very high83.5Confident0 Ų047.1 Ų47.10%024%0.238CC..EExtended strand (participates in β ladder)trans-112.5126.9176.4-177.20000108.9L145 L148 V402 L585 V586 L588 F589L145-V599 HydrophobicContact CD1-CG1 4.08Å; L148-V599 HydrophobicContact CD2-CG1 4.34Å; V402-V599 HydrophobicContact CG2-CB 4.49Å; V402-V599 HydrophobicContact CG2-CG1 4.07Å; V402-V599 HydrophobicContact CG2-CG2 3.86Å; L585-V599 WeakPolarHBondContact CA-O 3.12Å; V586-V599 PolarHBondContact N-O 3.45Å; V586-V599 PolarHBondContact O-N 2.85Å; L588-V599 HydrophobicContact CB-CB 4.43Å; L588-V599 HydrophobicContact CB-CG2 3.71Å; L588-V599 HydrophobicContact CD2-CB 4.48Å; L588-V599 HydrophobicContact CD2-CG2 3.76Å; L588-V599 HydrophobicContact CG-CG2 4.39Å; F589-V599 HydrophobicContact CE2-CG2 4.38Å; F589-V599 HydrophobicContact CZ-CG2 4.28Å
600L97.3Very high81Confident2 Ų257.2 Ų57.21%0.0128%0.282CS..EExtended strand (participates in β ladder)trans-80.9125.1172-175.7156000109.1L387 I399 T400 S401 R572 L576 L585L387-L600 HydrophobicContact CD2-CD1 4.47Å; L387-L600 HydrophobicContact CD2-CD2 3.96Å; I399-L600 HydrophobicContact CG2-CD2 4.46Å; T400-L600 CarbonylContact C-O 3.59Å; T400-L600 WeakPolarHBondContact CA-O 3.23Å; S401-L600 PolarHBondContact N-O 3.41Å; S401-L600 PolarHBondContact O-N 3.22Å; R572-L600 HydrophobicContact CB-CD1 3.63Å; L576-L600 HydrophobicContact CD1-CD2 3.95Å; L585-L600 HydrophobicContact CD2-CB 3.9Å; L585-L600 HydrophobicContact CD2-CG 4.47Å
601M96.4Very high78.7Confident25 Ų2564.2 Ų64.212%0.12331%0.314CS..EExtended strand (participates in β ladder)trans-116.5140.5173.4-172.6-162.1-62.100110.1L148 L152 I399 T400 S583 Q584 V586L148-M601 HydrophobicContact CD1-CE 3.58Å; L148-M601 HydrophobicContact CD2-CE 3.84Å; L148-M601 HydrophobicContact CG-CE 3.83Å; L152-M601 HydrophobicContact CD1-CE 3.86Å; L152-M601 HydrophobicContact CD1-CG 4.05Å; L152-M601 HydrophobicContact CD1-SD 3.93Å; L152-M601 HydrophobicContact CD2-CG 4.16Å; L152-M601 HydrophobicContact CG-CG 4.44Å; L152-M601 HydrophobicContact CG-SD 4.48Å; I399-M601 WeakPolarHBondContact O-CA 3.4Å; T400-M601 HydrophobicContact CG2-CG 4.39Å; S583-M601 CarbonylContact C-O 3.52Å; S583-M601 VanDerWaalsContact CA-O 3.27Å; S583-M601 WeakPolarHBondContact CA-O 3.36Å; S583-M601 WeakPolarHBondContact CB-O 3.48Å; Q584-M601 PolarHBondContact N-O 3.26Å; Q584-M601 PolarHBondContact O-N 3.03Å; V586-M601 HydrophobicContact CG2-CE 4.13Å
602A96.4Very high76.3Confident3 Ų369.3 Ų69.33%0.02535%0.345CS..EExtended strand (participates in β ladder)trans-149.3156.316500000111.3F390 G398 I399 L576 I581F390-A602 HydrophobicContact CE1-CB 3.59Å; F390-A602 HydrophobicContact CZ-CB 3.74Å; G398-A602 CarbonylContact C-O 3.59Å; G398-A602 VanDerWaalsContact CA-O 3.25Å; G398-A602 WeakPolarHBondContact CA-O 3.47Å; I399-A602 HydrophobicContact CG2-CB 3.86Å; I399-A602 PolarHBondContact N-O 2.8Å; I399-A602 PolarHBondContact O-N 3.37Å; I399-A602 VanDerWaalsContact O-N 3.14Å; L576-A602 HydrophobicContact CD1-CB 3.74Å; I581-A602 HydrophobicContact CG2-CB 4Å
603L94.8Very high73.9Confident60 Ų6077.7 Ų77.731%0.31438%0.38SS..EExtended strand (participates in β ladder)trans-130.5141.3176.5-66179.8000109.9L152 T156L152-L603 HydrophobicContact CD2-CD2 3.84Å; L152-L603 HydrophobicContact CG-CD2 4.01Å; T156-L603 HydrophobicContact CG2-CD2 3.89Å
604K92.7Very high71.4Confident40 Ų4081.5 Ų81.517%0.17441%0.409CS..PPolyproline II helixtrans-84.1131.1164.5-65.6-168-175.2-175.60109.3F390 V391 C393 V396 R397F390-K604 HydrophobicContact CE2-CG 3.86Å; F390-K604 HydrophobicContact CZ-CG 4.11Å; F390-K604 WeakPolarHBondContact O-CE 3.47Å; F390-K604 PolarHBondContact O-NZ 3.04Å; V391-K604 PolarHBondContact O-NZ 2.97Å; C393-K604 PolarHBondContact O-NZ 3.27Å; V396-K604 WeakPolarHBondContact O-CD 3.47Å; R397-K604 PolarHBondContact NH2-O 3.14Å; R397-K604 PolarHBondContact O-N 3.01Å
605Q78.9Confident69Low160 Ų16087.4 Ų87.475%0.74845%0.446SS*.PPolyproline II helixtrans-57.1147.7167.2-69.8-170.6-9.600110.1R397 T607R397-Q605 PolarHBondContact NH2-O 3.38Å; Q605-T607 PolarHBondContact O-N 3.37Å
606P66.7Low66.1Low104 Ų10494.7 Ų94.768%0.67548%0.483SS*.PPolyproline II helixtrans-48.9129.8167.6-26.835.6000109.4R608P606-R608 VanDerWaalsContact C-N 3.3Å; P606-R608 PolarHBondContact O-N 3.27Å
607T55.9Low63.5Low104 Ų104102.9 Ų102.964%0.63854%0.539SS*.  trans-62.8100.9162.733.10000105.7Q605 D609Q605-T607 PolarHBondContact O-N 3.37Å; T607-D609 PolarHBondContact O-N 2.72Å
608R43.4Very low62Low236 Ų236108 Ų10889%0.89157%0.566SS**  trans-65.3116.1160.4-71.6-175.6176.6-172.6-2.7105.5P606P606-R608 VanDerWaalsContact C-N 3.3Å; P606-R608 PolarHBondContact O-N 3.27Å
609D41.5Very low60.3Low129 Ų129113.4 Ų113.469%0.6959%0.594SS**  trans-57.4142.5179.2-54.4-64.8000109.6T607 E611T607-D609 PolarHBondContact O-N 2.72Å; D609-E611 PolarHBondContact O-N 2.72Å
610K38.5Very low58.3Low213 Ų213119.7 Ų119.793%0.92663%0.627SS**SBendtrans-78.942.3178.4-73.8-167.5171.4-169.20111.5
611E41.2Very low56Low167 Ų167126.6 Ų126.678%0.7866%0.663SS**  trans-12759-176-63.9-160.3159.900110.7D609D609-E611 PolarHBondContact O-N 2.72Å
612T36Very low53.4Low126 Ų126132.9 Ų132.977%0.77370%0.697SS**  trans-166.245.3151.110.60000112.3C614T612-C614 PolarHBondContact O-N 2.82Å
613E34.7Very low50.6Low195 Ų195141.6 Ų141.691%0.91174%0.742SS**  trans-83.945.2152.4-160.3156.6-12800109.5T615E613-T615 PolarHBondContact O-N 2.99Å; E613-T615 VanDerWaalsContact O-N 3.13Å
614C32.3Very low47.4Very low108 Ų108147.4 Ų147.473%0.7377%0.773SS**  trans-74.5100.1171.7-72.50000108.2T612 L616T612-C614 PolarHBondContact O-N 2.82Å; C614-L616 PolarHBondContact O-N 2.85Å
615T40.2Very low43.9Very low125 Ų125155.7 Ų155.777%0.76782%0.819SS**  trans-46.1134.4160.149.80000111.1E613E613-T615 PolarHBondContact O-N 2.99Å; E613-T615 VanDerWaalsContact O-N 3.13Å
616L26.4Very low41Very low162 Ų162155.3 Ų155.385%0.84883%0.825SS**  trans161.9141.8139.2-90.3162.2000110.7C614C614-L616 PolarHBondContact O-N 2.85Å
617P35.5Very low38.7Very low195 Ų195160 Ų160100%1.26684%0.838SS**  cis-111.20-28.919.90.7000113

Retrieved 617 of 617 residues in 645.6 ms (Link to these results)