A0A060XA66_ONCMY Loading...

G-protein coupled receptor 83

G-protein coupled receptor for PEN, a neuropeptide produced from the precursor protein, proSAAS (encoded by PCSK1N). Acts through a G(i)- and G(q)-alpha-alpha-mediated pathway in response to PEN. Plays a role in food intake and body weight regulation. May contribute to the regulation of anxiety-related behaviors.

AlphaFold DB , UniProt , Accession A0A060XA66, Species ONCMY (Oncorhynchus mykiss, Rainbow trout), Gene n/a, Length 441 aa.

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(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	38.1	Very low	49.9	Very low	215 Å²	215	85.3 Å²	85.3	100%	1.059	45%	0.45	S	S	*	.				0	-53.2	0	-74.4	-173	176.8	0	0	114.6	G3 A4 C5	M1-G3 PolarHBondContact O-N 3.39Å; M1-A4 WeakPolarHBondContact O-CB 3.49Å; M1-A4 PolarHBondContact O-N 3.14Å; M1-A4 VanDerWaalsContact O-N 3.13Å; M1-C5 PolarHBondContact O-N 3.11Å
2	R	38.1	Very low	50.2	Low	231 Å²	231	83.5 Å²	83.5	87%	0.872	43%	0.434	S	S	*	.	H	α-helix	trans	-51.3	-47.6	-174	-73.1	-175.4	177.3	177.7	-0.7	114.7	A4 C5 L6	R2-A4 VanDerWaalsContact C-N 3.34Å; R2-A4 PolarHBondContact O-N 3.3Å; R2-C5 WeakPolarHBondContact O-CB 3.47Å; R2-C5 PolarHBondContact O-N 3.38Å; R2-L6 PolarHBondContact O-N 3.49Å; R2-L6 VanDerWaalsContact O-N 3.14Å
3	G	43.2	Very low	50.9	Low	55 Å²	55	86.3 Å²	86.3	57%	0.567	45%	0.449	S	S	*	.	H	α-helix	trans	-58.3	-38.8	178.6	0	0	0	0	0	114.5	M1 C5 L6 W7	M1-G3 PolarHBondContact O-N 3.39Å; G3-C5 VanDerWaalsContact C-N 3.32Å; G3-C5 PolarHBondContact O-N 3.38Å; G3-L6 PolarHBondContact O-N 3.37Å; G3-W7 PolarHBondContact O-N 2.91Å
4	A	43.9	Very low	50.9	Low	33 Å²	33	86.1 Å²	86.1	27%	0.273	47%	0.466	S	S	.	.	H	α-helix	trans	-61.9	-38.9	174.6	0	0	0	0	0	112.1	M1 R2 L8 F104	M1-A4 WeakPolarHBondContact O-CB 3.49Å; M1-A4 PolarHBondContact O-N 3.14Å; M1-A4 VanDerWaalsContact O-N 3.13Å; R2-A4 VanDerWaalsContact C-N 3.34Å; R2-A4 PolarHBondContact O-N 3.3Å; A4-L8 VanDerWaalsContact O-CB 3.26Å; A4-L8 WeakPolarHBondContact O-CB 3.28Å; A4-L8 WeakPolarHBondContact O-CG 3.44Å; A4-L8 PolarHBondContact O-N 3.49Å; A4-F104 HydrophobicContact CB-CD2 4.28Å; A4-F104 HydrophobicContact CB-CE2 3.51Å; A4-F104 HydrophobicContact CB-CZ 3.89Å
5	C	47.1	Very low	50.6	Low	42 Å²	42	81.1 Å²	81.1	28%	0.284	44%	0.441	S	S	.	.	H	α-helix	trans	-67.8	-37	177.1	-59.1	0	0	0	0	111.8	M1 R2 G3 S9	M1-C5 PolarHBondContact O-N 3.11Å; R2-C5 WeakPolarHBondContact O-CB 3.47Å; R2-C5 PolarHBondContact O-N 3.38Å; G3-C5 VanDerWaalsContact C-N 3.32Å; G3-C5 PolarHBondContact O-N 3.38Å; C5-S9 PolarHBondContact O-N 3.11Å; C5-S9 VanDerWaalsContact O-N 3.11Å; C5-S9 PolarHBondContact O-OG 3.06Å
6	L	56.4	Low	50	Low	124 Å²	124	79.4 Å²	79.4	65%	0.649	44%	0.437	S	S	*	.	H	α-helix	trans	-64.8	-49.2	176.5	-143.6	89.7	0	0	0	111.1	R2 G3 S9 L10	R2-L6 PolarHBondContact O-N 3.49Å; R2-L6 VanDerWaalsContact O-N 3.14Å; G3-L6 PolarHBondContact O-N 3.37Å; L6-S9 WeakPolarHBondContact O-CA 3.47Å; L6-S9 WeakPolarHBondContact O-CB 3.2Å; L6-S9 PolarHBondContact O-N 3.4Å; L6-L10 PolarHBondContact O-N 3.34Å
7	W	54.3	Low	49.6	Very low	64 Å²	64	80.4 Å²	80.4	24%	0.242	45%	0.448	C	S	.	.	H	α-helix	trans	-69.2	-35.6	-179.3	-165.9	91.1	0	0	0	112.9	G3 S9 L10 T11 I101 F104 F360	G3-W7 PolarHBondContact O-N 2.91Å; W7-S9 PolarHBondContact O-N 3.06Å; W7-L10 PolarHBondContact O-N 3.5Å; W7-T11 HydrophobicContact CD2-CG2 3.86Å; W7-T11 HydrophobicContact CE3-CG2 3.7Å; W7-T11 HydrophobicContact CH2-CG2 3.69Å; W7-T11 HydrophobicContact CZ2-CG2 3.83Å; W7-T11 HydrophobicContact CZ3-CG2 3.61Å; W7-T11 WeakPolarHBondContact O-CG2 3.34Å; W7-T11 PolarHBondContact O-N 3.26Å; W7-T11 PolarHBondContact O-OG1 3.35Å; W7-I101 HydrophobicContact CH2-CG2 3.98Å; W7-I101 HydrophobicContact CZ2-CB 4.23Å; W7-I101 HydrophobicContact CZ2-CD1 4.07Å; W7-I101 HydrophobicContact CZ2-CG1 3.76Å; W7-I101 HydrophobicContact CZ2-CG2 3.69Å; W7-F104 HydrophobicContact CD2-CD1 4.48Å; W7-F104 AromaticContact CE3-CD1 3.58Å; W7-F104 HydrophobicContact CE3-CD1 3.58Å; W7-F104 AromaticContact CE3-CE1 3.55Å; W7-F104 HydrophobicContact CE3-CE1 3.55Å; W7-F104 HydrophobicContact CH2-CD1 4.45Å; W7-F104 AromaticContact CZ3-CD1 3.56Å; W7-F104 HydrophobicContact CZ3-CD1 3.56Å; W7-F104 AromaticContact CZ3-CE1 3.75Å; W7-F104 HydrophobicContact CZ3-CE1 3.75Å; W7-F360 HydrophobicContact CH2-CE1 4.34Å; W7-F360 AromaticContact CH2-CE2 3.97Å; W7-F360 HydrophobicContact CH2-CE2 3.97Å; W7-F360 AromaticContact CH2-CZ 3.69Å; W7-F360 HydrophobicContact CH2-CZ 3.69Å; W7-F360 HydrophobicContact CZ2-CE1 4.25Å; W7-F360 HydrophobicContact CZ2-CE2 4.09Å; W7-F360 AromaticContact CZ2-CZ 3.49Å; W7-F360 HydrophobicContact CZ2-CZ 3.49Å; W7-F360 VanDerWaalsContact CZ2-CZ 3.49Å
8	L	57.7	Low	49.2	Very low	13 Å²	13	83.3 Å²	83.3	7%	0.068	46%	0.462	C	S	.	.	H	α-helix	trans	-61.5	-31	168.3	-76.7	179.9	0	0	0	113.1	A4 T11 Y12 F104 L108 L373 L377	A4-L8 VanDerWaalsContact O-CB 3.26Å; A4-L8 WeakPolarHBondContact O-CB 3.28Å; A4-L8 WeakPolarHBondContact O-CG 3.44Å; A4-L8 PolarHBondContact O-N 3.49Å; L8-T11 WeakPolarHBondContact CA-OG1 3.32Å; L8-T11 PolarHBondContact O-OG1 2.92Å; L8-Y12 VanDerWaalsContact O-CB 3.24Å; L8-Y12 WeakPolarHBondContact O-CB 3.43Å; L8-Y12 PolarHBondContact O-N 3.34Å; L8-Y12 VanDerWaalsContact O-N 3.08Å; L8-F104 HydrophobicContact CD1-CZ 4Å; L8-F104 HydrophobicContact CD2-CE1 3.72Å; L8-F104 HydrophobicContact CD2-CZ 3.86Å; L8-F104 HydrophobicContact CG-CE1 3.92Å; L8-F104 HydrophobicContact CG-CZ 3.7Å; L8-L108 HydrophobicContact CD2-CD2 3.68Å; L8-L373 HydrophobicContact CD2-CD1 3.81Å; L8-L373 HydrophobicContact CD2-CD2 4.47Å; L8-L377 HydrophobicContact CB-CD1 4.38Å; L8-L377 HydrophobicContact CB-CD2 3.69Å; L8-L377 HydrophobicContact CB-CG 4.24Å; L8-L377 HydrophobicContact CD1-CD2 4.28Å
9	S	59.3	Low	48.4	Very low	47 Å²	47	82.9 Å²	82.9	33%	0.329	48%	0.48	S	S	.	.	H	α-helix	trans	-74.4	-43.4	175.4	-54.8	0	0	0	0	111	C5 L6 W7 Y12 L13	C5-S9 PolarHBondContact O-N 3.11Å; C5-S9 VanDerWaalsContact O-N 3.11Å; C5-S9 PolarHBondContact O-OG 3.06Å; L6-S9 WeakPolarHBondContact O-CA 3.47Å; L6-S9 WeakPolarHBondContact O-CB 3.2Å; L6-S9 PolarHBondContact O-N 3.4Å; W7-S9 PolarHBondContact O-N 3.06Å; S9-Y12 PolarHBondContact O-N 3.23Å; S9-L13 WeakPolarHBondContact O-CG 3.44Å; S9-L13 PolarHBondContact O-N 3.17Å
10	L	58.6	Low	47.6	Very low	101 Å²	101	87.9 Å²	87.9	53%	0.529	50%	0.503	S	S	.	.	H	α-helix	trans	-61.6	-44.8	175.3	-68.8	169.9	0	0	0	112.6	L6 W7 Y12 L13 A14	L6-L10 PolarHBondContact O-N 3.34Å; W7-L10 PolarHBondContact O-N 3.5Å; L10-Y12 VanDerWaalsContact C-N 3.33Å; L10-Y12 PolarHBondContact O-N 3.49Å; L10-L13 PolarHBondContact O-N 2.96Å; L10-A14 WeakPolarHBondContact O-CB 3.41Å; L10-A14 PolarHBondContact O-N 3.03Å
11	T	52.1	Low	46.8	Very low	13 Å²	13	87.2 Å²	87.2	8%	0.08	52%	0.516	C	S	.	.	H	α-helix	trans	-70.8	-26.5	176.2	51.8	0	0	0	0	113.5	W7 L8 A15 F360	W7-T11 HydrophobicContact CD2-CG2 3.86Å; W7-T11 HydrophobicContact CE3-CG2 3.7Å; W7-T11 HydrophobicContact CH2-CG2 3.69Å; W7-T11 HydrophobicContact CZ2-CG2 3.83Å; W7-T11 HydrophobicContact CZ3-CG2 3.61Å; W7-T11 WeakPolarHBondContact O-CG2 3.34Å; W7-T11 PolarHBondContact O-N 3.26Å; W7-T11 PolarHBondContact O-OG1 3.35Å; L8-T11 WeakPolarHBondContact CA-OG1 3.32Å; L8-T11 PolarHBondContact O-OG1 2.92Å; T11-A15 VanDerWaalsContact O-CB 3.32Å; T11-A15 WeakPolarHBondContact O-CB 3.19Å; T11-A15 PolarHBondContact O-N 3.02Å; T11-F360 HydrophobicContact CG2-CD1 4.18Å; T11-F360 HydrophobicContact CG2-CE1 3.57Å; T11-F360 HydrophobicContact CG2-CZ 4.19Å
12	Y	53.3	Low	46.3	Very low	64 Å²	64	81.7 Å²	81.7	25%	0.251	50%	0.504	S	S	.	.	H	α-helix	trans	-70.4	-42.1	169.5	-178.4	-92.2	0	0	0	111.8	L8 S9 L10 A15 S16 R374	L8-Y12 VanDerWaalsContact O-CB 3.24Å; L8-Y12 WeakPolarHBondContact O-CB 3.43Å; L8-Y12 PolarHBondContact O-N 3.34Å; L8-Y12 VanDerWaalsContact O-N 3.08Å; S9-Y12 PolarHBondContact O-N 3.23Å; L10-Y12 VanDerWaalsContact C-N 3.33Å; L10-Y12 PolarHBondContact O-N 3.49Å; Y12-A15 PolarHBondContact O-N 3.25Å; Y12-S16 PolarHBondContact O-N 3.44Å; Y12-R374 HydrophobicContact CD2-CG 4.23Å; Y12-R374 HydrophobicContact CE2-CG 3.57Å
13	L	59.8	Low	45.8	Very low	120 Å²	120	82.3 Å²	82.3	63%	0.628	51%	0.506	S	S	*	.	H	α-helix	trans	-61.2	-49.5	175.5	-73.3	165.5	0	0	0	111.4	S9 L10 A15 S16	S9-L13 WeakPolarHBondContact O-CG 3.44Å; S9-L13 PolarHBondContact O-N 3.17Å; L10-L13 PolarHBondContact O-N 2.96Å; L13-A15 PolarHBondContact O-N 3.12Å; L13-S16 PolarHBondContact O-N 2.83Å; L13-S16 VanDerWaalsContact O-N 3.09Å
14	A	50.3	Low	45.1	Very low	84 Å²	84	88.1 Å²	88.1	69%	0.694	52%	0.519	S	S	*	.	T	Hydrogen-bonded Turn	trans	-62.8	-12.4	176.2	0	0	0	0	0	114.4	L10	L10-A14 WeakPolarHBondContact O-CB 3.41Å; L10-A14 PolarHBondContact O-N 3.03Å
15	A	46.4	Very low	44.1	Very low	11 Å²	11	97.8 Å²	97.8	9%	0.091	55%	0.55	C	S	.	.	T	Hydrogen-bonded Turn	trans	-106.9	5.7	178.4	0	0	0	0	0	113.6	T11 Y12 L13 R370	T11-A15 VanDerWaalsContact O-CB 3.32Å; T11-A15 WeakPolarHBondContact O-CB 3.19Å; T11-A15 PolarHBondContact O-N 3.02Å; Y12-A15 PolarHBondContact O-N 3.25Å; L13-A15 PolarHBondContact O-N 3.12Å; A15-R370 VanDerWaalsContact O-CZ 3.27Å; A15-R370 PolarHBondContact O-NH1 3.42Å; A15-R370 PolarHBondContact O-NH2 2.94Å
16	S	40.9	Very low	43.1	Very low	53 Å²	53	100.3 Å²	100.3	37%	0.371	57%	0.568	S	S	.	*			trans	-86.7	118.5	177.6	-155.3	0	0	0	0	110.8	Y12 L13 D18	Y12-S16 PolarHBondContact O-N 3.44Å; L13-S16 PolarHBondContact O-N 2.83Å; L13-S16 VanDerWaalsContact O-N 3.09Å; S16-D18 VanDerWaalsContact C-N 3.3Å; S16-D18 PolarHBondContact O-N 3.05Å
17	P	42.9	Very low	41.6	Very low	96 Å²	96	101.3 Å²	101.3	62%	0.623	57%	0.574	S	S	*	*			trans	-87	2.5	-176.2	37.3	-36.3	0	0	0	113.7
18	D	42.7	Very low	40.3	Very low	133 Å²	133	103 Å²	103	71%	0.711	60%	0.595	S	S	*	*			trans	-109.4	112.6	-169	-48.3	-61.8	0	0	0	109.6	S16	S16-D18 VanDerWaalsContact C-N 3.3Å; S16-D18 PolarHBondContact O-N 3.05Å
19	G	34	Very low	38.6	Very low	77 Å²	77	108.4 Å²	108.4	79%	0.794	63%	0.629	S	S	*	*			trans	125.4	52.2	163.3	0	0	0	0	0	119.3
20	L	33.8	Very low	37	Very low	182 Å²	182	111.7 Å²	111.7	95%	0.953	65%	0.647	S	S	*	*			trans	-149.6	132.4	146.8	-111.3	158.7	0	0	0	109
21	G	29.8	Very low	35.3	Very low	74 Å²	74	114.8 Å²	114.8	76%	0.763	66%	0.662	S	S	*	*			trans	-74.2	149	-163	0	0	0	0	0	114.5
22	A	28.5	Very low	33.9	Very low	98 Å²	98	117.9 Å²	117.9	81%	0.81	70%	0.697	S	S	*	*			trans	-70.5	151	170.9	0	0	0	0	0	111.5
23	R	26	Very low	32.5	Very low	244 Å²	244	118.4 Å²	118.4	92%	0.921	72%	0.722	S	S	*	*			trans	-136.2	103.7	156.1	-155.9	172.3	-165.5	167	3.9	107.9
24	E	28.8	Very low	30.7	Very low	177 Å²	177	119.3 Å²	119.3	83%	0.827	73%	0.732	S	S	*	*			trans	-73.5	143.5	176.1	-66.3	174.1	117.6	0	0	110.2
25	Y	24	Very low	29.4	Very low	237 Å²	237	122.5 Å²	122.5	93%	0.929	74%	0.737	S	S	*	*			trans	-141.6	139.5	147.3	-114.8	-89	0	0	0	106.9
26	S	25.4	Very low	28.3	Very low	95 Å²	95	131 Å²	131	66%	0.664	77%	0.772	S	S	*	*			trans	-125.4	161.5	-168.8	-169.2	0	0	0	0	111.7
27	N	26	Very low	27.5	Very low	144 Å²	144	134.9 Å²	134.9	77%	0.77	79%	0.793	S	S	*	*			trans	74.2	139	171.6	-49.6	-7.1	0	0	0	114.2
28	S	25.6	Very low	26.6	Very low	100 Å²	100	137.3 Å²	137.3	70%	0.699	80%	0.801	S	S	*	*			cis	-162.1	-169	-15	-80.8	0	0	0	0	106.7
29	T	23.3	Very low	25.7	Very low	126 Å²	126	134.8 Å²	134.8	77%	0.773	80%	0.798	S	S	*	*			cis	-162.7	176.9	9.7	-21	0	0	0	0	110.1
30	V	23.8	Very low	25.3	Very low	116 Å²	116	140.8 Å²	140.8	70%	0.703	81%	0.806	S	S	*	*			trans	76.5	105.7	145.1	164.5	0	0	0	0	121.1
31	I	23.5	Very low	24.9	Very low	167 Å²	167	135.6 Å²	135.6	86%	0.856	80%	0.796	S	S	*	*			trans	63.7	133.4	130	-55.1	177.4	0	0	0	121.8
32	G	23.4	Very low	24.7	Very low	78 Å²	78	140.3 Å²	140.3	80%	0.804	80%	0.803	S	S	*	*			trans	120.8	130.1	163.6	0	0	0	0	0	112.7
33	G	24	Very low	24.5	Very low	75 Å²	75	143.2 Å²	143.2	77%	0.773	80%	0.804	S	S	*	*			cis	-171.3	160.3	-6.3	0	0	0	0	0	108.5
34	V	22.6	Very low	24.4	Very low	139 Å²	139	138.8 Å²	138.8	84%	0.842	80%	0.798	S	S	*	*			trans	-134.6	129.9	-167.4	175.6	0	0	0	0	113.5
35	L	21.4	Very low	24.3	Very low	151 Å²	151	138.6 Å²	138.6	79%	0.791	80%	0.802	S	S	*	*			trans	68.2	131.1	165.4	-104.1	68.4	0	0	0	121.1
36	F	24.4	Very low	24.4	Very low	189 Å²	189	131.9 Å²	131.9	83%	0.829	79%	0.79	S	S	*	*				17.8	129.3	129.5	-79.9	-103.4	0	0	0	120.6
37	V	24.3	Very low	24.5	Very low	134 Å²	134	134.1 Å²	134.1	81%	0.812	80%	0.795	S	S	*	*				-144.5	155.4	126	176.9	0	0	0	0	108.8
38	D	22.6	Very low	24.8	Very low	147 Å²	147	131.8 Å²	131.8	79%	0.786	79%	0.787	S	S	*	*			trans	-51.1	-172.7	163.1	-57.7	-77.2	0	0	0	114.8
39	A	23.9	Very low	24.7	Very low	80 Å²	80	138 Å²	138	66%	0.661	80%	0.797	S	S	*	*			cis	-176.4	170	-43.2	0	0	0	0	0	107.2
40	E	26.2	Very low	24.8	Very low	203 Å²	203	138.6 Å²	138.6	95%	0.949	80%	0.801	S	S	*	*			trans	61.5	167.3	176	-56	-144.8	126.2	0	0	117.7
41	G	25.3	Very low	25	Very low	73 Å²	73	137.6 Å²	137.6	75%	0.753	80%	0.799	S	S	*	*			trans	102.2	48.3	166.4	0	0	0	0	0	118.1
42	L	24.8	Very low	25	Very low	174 Å²	174	136.5 Å²	136.5	91%	0.911	80%	0.795	S	S	*	*			trans	-154.8	59.3	157.8	-118.4	172.4	0	0	0	114.2
43	L	25.9	Very low	25.4	Very low	159 Å²	159	141.2 Å²	141.2	83%	0.832	80%	0.801	S	S	*	*			trans	-93.2	125.4	155.2	-80.5	173.1	0	0	0	108.8
44	N	23	Very low	25.7	Very low	150 Å²	150	143.2 Å²	143.2	80%	0.802	80%	0.798	S	S	*	*			trans	158.1	103.9	130.7	-81.8	-16.1	0	0	0	111.5
45	L	27.1	Very low	25.9	Very low	173 Å²	173	144.1 Å²	144.1	91%	0.906	80%	0.798	S	S	*	*			trans	-151.1	106.5	136.4	-110	166.2	0	0	0	107.2
46	S	26.1	Very low	26.2	Very low	97 Å²	97	143.6 Å²	143.6	68%	0.678	80%	0.801	S	S	*	*			trans	-64.7	168.9	160.7	49.9	0	0	0	0	108.9
47	D	26.4	Very low	26.3	Very low	142 Å²	142	144.5 Å²	144.5	76%	0.759	81%	0.805	S	S	*	*			cis	-159.1	-165.4	39.7	-143	1.4	0	0	0	111.3
48	P	32.4	Very low	26.5	Very low	95 Å²	95	143.3 Å²	143.3	62%	0.617	80%	0.803	S	S	*	*				-122.8	155.2	-112	38.9	-23.3	0	0	0	115.6
49	Y	24.1	Very low	26.7	Very low	230 Å²	230	144 Å²	144	90%	0.902	81%	0.805	S	S	*	*			trans	-157.3	104.1	146.2	-125.6	-82.3	0	0	0	110.7
50	T	26.4	Very low	26.8	Very low	138 Å²	138	148 Å²	148	85%	0.847	82%	0.815	S	S	*	*			trans	-123.3	115.4	177.3	50.3	0	0	0	0	111.4
51	S	26.5	Very low	27.1	Very low	95 Å²	95	145 Å²	145	66%	0.664	81%	0.805	S	S	*	*			trans	-149.5	151.4	156.8	56.8	0	0	0	0	110.6
52	N	24.3	Very low	27.4	Very low	144 Å²	144	148.5 Å²	148.5	77%	0.77	81%	0.807	S	S	*	*			trans	64.8	57.9	166.1	-55	-8	0	0	0	117.5	T54	N52-T54 PolarHBondContact O-N 2.56Å; N52-T54 VanDerWaalsContact O-N 3.11Å
53	L	31.7	Very low	27.7	Very low	178 Å²	178	148.3 Å²	148.3	93%	0.932	80%	0.801	S	S	*	*			trans	-78.3	70.9	156.8	-172	82.9	0	0	0	111
54	T	30.2	Very low	27.9	Very low	116 Å²	116	142.9 Å²	142.9	71%	0.712	78%	0.784	S	S	*	*			trans	-159.4	141.4	166.4	15.2	0	0	0	0	109.7	N52	N52-T54 PolarHBondContact O-N 2.56Å; N52-T54 VanDerWaalsContact O-N 3.11Å
55	N	27.4	Very low	28.6	Very low	158 Å²	158	139.9 Å²	139.9	85%	0.845	77%	0.771	S	S	*	*			trans	88.3	48.3	-178.8	-53	-13.8	0	0	0	117.9
56	V	26.6	Very low	29	Very low	140 Å²	140	136.9 Å²	136.9	85%	0.848	76%	0.755	S	S	*	*			trans	-129.3	60.6	160.5	-166.7	0	0	0	0	110.3
57	F	27.9	Very low	29.4	Very low	209 Å²	209	135.1 Å²	135.1	92%	0.917	75%	0.747	S	S	*	*			trans	-149.2	45.2	174.4	-114.4	-71.6	0	0	0	113.3
58	S	26.9	Very low	30	Very low	109 Å²	109	133.3 Å²	133.3	76%	0.762	74%	0.737	S	S	*	*			trans	-149.5	108.2	160.1	-66.1	0	0	0	0	108.4
59	L	27.6	Very low	30.2	Very low	162 Å²	162	136.3 Å²	136.3	85%	0.848	74%	0.736	S	S	*	*			trans	-135	105	160.9	-84	175.3	0	0	0	106.4	L61	L59-L61 PolarHBondContact O-N 3.21Å
60	D	27	Very low	30.9	Very low	162 Å²	162	130.7 Å²	130.7	87%	0.866	72%	0.718	S	S	*	*			trans	-59	130.6	171.1	-55.9	-74.5	0	0	0	109
61	L	30.6	Very low	31.3	Very low	140 Å²	140	127 Å²	127	73%	0.733	70%	0.698	S	S	*	*			trans	-133.5	53.3	-173.4	-151.1	90.3	0	0	0	112	L59	L59-L61 PolarHBondContact O-N 3.21Å
62	D	32.6	Very low	31.7	Very low	148 Å²	148	127.6 Å²	127.6	79%	0.791	69%	0.691	S	S	*	*	S	Bend	trans	-113.4	162	172.7	-157.8	-1.1	0	0	0	111.3	G64	D62-G64 PolarHBondContact O-N 3.37Å
63	E	31.9	Very low	32.6	Very low	169 Å²	169	123.1 Å²	123.1	79%	0.79	68%	0.675	S	S	*	*	S	Bend	trans	54.7	-41.3	-173.8	-69.8	-163.7	99.9	0	0	118.2	T65 L66	E63-T65 PolarHBondContact O-N 2.91Å; E63-L66 PolarHBondContact O-N 3.24Å
64	G	30.2	Very low	32.6	Very low	45 Å²	45	117.6 Å²	117.6	46%	0.464	66%	0.661	S	S	.	*	H	α-helix	trans	-63.1	-39.9	-165	0	0	0	0	0	115.5	D62 L66 A67 D68	D62-G64 PolarHBondContact O-N 3.37Å; G64-L66 VanDerWaalsContact C-N 3.33Å; G64-L66 PolarHBondContact O-N 2.99Å; G64-A67 PolarHBondContact O-N 2.95Å; G64-D68 PolarHBondContact O-N 2.89Å
65	T	37.2	Very low	32.8	Very low	87 Å²	87	120.5 Å²	120.5	53%	0.534	66%	0.663	S	S	.	*	H	α-helix	trans	-67.4	-31.2	-173.4	54.8	0	0	0	0	113.2	E63 W69	E63-T65 PolarHBondContact O-N 2.91Å; T65-W69 VanDerWaalsContact O-CD1 3.3Å; T65-W69 PolarHBondContact O-N 3.26Å
66	L	34.7	Very low	33.3	Very low	110 Å²	110	122.2 Å²	122.2	58%	0.576	66%	0.663	S	S	*	*	H	α-helix	trans	-70.5	-40.3	177.1	-166.7	69.1	0	0	0	110.9	E63 G64 D68 W69 H70	E63-L66 PolarHBondContact O-N 3.24Å; G64-L66 VanDerWaalsContact C-N 3.33Å; G64-L66 PolarHBondContact O-N 2.99Å; L66-D68 VanDerWaalsContact C-N 3.35Å; L66-D68 PolarHBondContact O-N 3.02Å; L66-W69 PolarHBondContact O-N 3.14Å; L66-H70 PolarHBondContact O-CD2 3.49Å; L66-H70 PolarHBondContact O-N 3.46Å
67	A	35.7	Very low	34.1	Very low	61 Å²	61	126.4 Å²	126.4	50%	0.504	66%	0.664	S	S	.	*	H	α-helix	trans	-62.4	-39.1	177.8	0	0	0	0	0	112.4	G64 W69 H70 S71	G64-A67 PolarHBondContact O-N 2.95Å; A67-W69 PolarHBondContact O-N 3.27Å; A67-H70 WeakPolarHBondContact O-CB 3.49Å; A67-H70 PolarHBondContact O-N 3.01Å; A67-S71 PolarHBondContact O-N 3Å
68	D	37.7	Very low	34.5	Very low	104 Å²	104	127.9 Å²	127.9	56%	0.556	67%	0.665	S	S	*	*	H	α-helix	trans	-65.9	-34.8	177	-96.7	-24.1	0	0	0	113.3	G64 L66 S71 M72	G64-D68 PolarHBondContact O-N 2.89Å; L66-D68 VanDerWaalsContact C-N 3.35Å; L66-D68 PolarHBondContact O-N 3.02Å; D68-S71 WeakPolarHBondContact O-CB 3.4Å; D68-S71 PolarHBondContact O-N 3.06Å; D68-M72 WeakPolarHBondContact O-CB 3.26Å; D68-M72 WeakPolarHBondContact O-CG 3.48Å; D68-M72 PolarHBondContact O-N 3.1Å
69	W	36.9	Very low	34.7	Very low	157 Å²	157	126.4 Å²	126.4	60%	0.595	67%	0.667	S	S	*	*	H	α-helix	trans	-65.4	-38.5	171.3	-82.6	105.7	0	0	0	112.5	T65 L66 A67 M72 A73	T65-W69 VanDerWaalsContact O-CD1 3.3Å; T65-W69 PolarHBondContact O-N 3.26Å; L66-W69 PolarHBondContact O-N 3.14Å; A67-W69 PolarHBondContact O-N 3.27Å; W69-M72 HydrophobicContact CD2-CE 4.08Å; W69-M72 HydrophobicContact CE3-CE 4.13Å; W69-M72 HydrophobicContact CG-CE 4.49Å; W69-M72 HydrophobicContact CZ3-CE 4.47Å; W69-A73 WeakPolarHBondContact O-CB 3.15Å; W69-A73 PolarHBondContact O-N 2.91Å
70	H	38.9	Very low	34.9	Very low	112 Å²	112	120.7 Å²	120.7	52%	0.519	65%	0.647	S	S	.	*	H	α-helix	trans	-65	-40.2	172	-82.9	-86.7	0	0	0	112.1	L66 A67 A73 G74	L66-H70 PolarHBondContact O-CD2 3.49Å; L66-H70 PolarHBondContact O-N 3.46Å; A67-H70 WeakPolarHBondContact O-CB 3.49Å; A67-H70 PolarHBondContact O-N 3.01Å; H70-A73 PolarHBondContact O-N 3.05Å; H70-G74 PolarHBondContact O-N 3Å
71	S	34	Very low	35.7	Very low	61 Å²	61	121.4 Å²	121.4	43%	0.427	65%	0.645	S	S	.	*	H	α-helix	trans	-61.5	-48.5	174.9	-177.8	0	0	0	0	112.3	A67 D68 A73 G74 K75	A67-S71 PolarHBondContact O-N 3Å; D68-S71 WeakPolarHBondContact O-CB 3.4Å; D68-S71 PolarHBondContact O-N 3.06Å; S71-A73 VanDerWaalsContact C-N 3.32Å; S71-A73 PolarHBondContact O-N 3.22Å; S71-G74 PolarHBondContact O-N 3.21Å; S71-K75 PolarHBondContact O-N 3.31Å
72	M	36.6	Very low	36.2	Very low	107 Å²	107	119.3 Å²	119.3	53%	0.527	64%	0.643	S	S	.	*	H	α-helix	trans	-63.7	-34.8	176	-75.7	-168	-80.2	0	0	113	D68 W69 G74 K75	D68-M72 WeakPolarHBondContact O-CB 3.26Å; D68-M72 WeakPolarHBondContact O-CG 3.48Å; D68-M72 PolarHBondContact O-N 3.1Å; W69-M72 HydrophobicContact CD2-CE 4.08Å; W69-M72 HydrophobicContact CE3-CE 4.13Å; W69-M72 HydrophobicContact CG-CE 4.49Å; W69-M72 HydrophobicContact CZ3-CE 4.47Å; M72-G74 VanDerWaalsContact C-N 3.31Å; M72-G74 PolarHBondContact O-N 3.38Å; M72-K75 PolarHBondContact O-N 3.02Å
73	A	41.4	Very low	36.9	Very low	51 Å²	51	119.2 Å²	119.2	42%	0.421	64%	0.637	S	S	.	*	H	α-helix	trans	-66.5	-31.1	175.6	0	0	0	0	0	112.9	W69 H70 S71	W69-A73 WeakPolarHBondContact O-CB 3.15Å; W69-A73 PolarHBondContact O-N 2.91Å; H70-A73 PolarHBondContact O-N 3.05Å; S71-A73 VanDerWaalsContact C-N 3.32Å; S71-A73 PolarHBondContact O-N 3.22Å
74	G	31.6	Very low	38.7	Very low	62 Å²	62	115.6 Å²	115.6	64%	0.639	62%	0.623	S	S	*	*	H	α-helix	trans	-75.6	-32.1	176.8	0	0	0	0	0	114.6	H70 S71 M72 K76	H70-G74 PolarHBondContact O-N 3Å; S71-G74 PolarHBondContact O-N 3.21Å; M72-G74 VanDerWaalsContact C-N 3.31Å; M72-G74 PolarHBondContact O-N 3.38Å; G74-K76 PolarHBondContact O-N 2.96Å
75	K	35.3	Very low	41.2	Very low	177 Å²	177	116.1 Å²	116.1	77%	0.77	62%	0.624	S	S	*	*	H	α-helix	trans	-78.8	-14.6	-170.2	-105.5	171.6	179.7	168.1	0	116.1	S71 M72 R77	S71-K75 PolarHBondContact O-N 3.31Å; M72-K75 PolarHBondContact O-N 3.02Å; K75-R77 PolarHBondContact O-N 3.4Å
76	K	38.2	Very low	43.6	Very low	194 Å²	194	116 Å²	116	84%	0.843	62%	0.623	S	S	*	*			trans	-89	77.8	177.7	-79.2	-173	174.8	176.5	0	112.7	G74	G74-K76 PolarHBondContact O-N 2.96Å
77	R	42.9	Very low	45.9	Very low	227 Å²	227	114.5 Å²	114.5	86%	0.857	62%	0.618	S	S	*	*			trans	-124.3	142.4	166.8	-136.1	175.4	-175.9	-177	-0.3	110.1	K75	K75-R77 PolarHBondContact O-N 3.4Å
78	Y	35.9	Very low	48.3	Very low	240 Å²	240	115.4 Å²	115.4	94%	0.941	61%	0.611	S	S	*	*	S	Bend	trans	67.4	130.9	-171.8	-97.6	-106	0	0	0	116.8
79	G	31.3	Very low	50.8	Low	79 Å²	79	114 Å²	114	81%	0.814	61%	0.609	S	S	*	*	S	Bend	trans	129.4	82	176	0	0	0	0	0	115.3
80	G	33.1	Very low	53.3	Low	41 Å²	41	111.9 Å²	111.9	42%	0.423	61%	0.609	S	S	.	*			trans	84.3	59.9	156.6	0	0	0	0	0	118.2	S82 Q83	G80-S82 PolarHBondContact O-N 3.4Å; G80-Q83 WeakPolarHBondContact O-CB 3.22Å; G80-Q83 PolarHBondContact O-N 2.89Å; G80-Q83 VanDerWaalsContact O-N 3.12Å
81	E	43	Very low	55.6	Low	177 Å²	177	107.4 Å²	107.4	83%	0.827	59%	0.589	S	S	*	*	H	α-helix	trans	-60.1	-29.7	175.7	-163.5	152.7	-148.2	0	0	113.5	N84	E81-N84 PolarHBondContact O-N 2.88Å
82	S	40.1	Very low	58.3	Low	97 Å²	97	107.4 Å²	107.4	68%	0.678	59%	0.586	S	S	*	*	H	α-helix	trans	-61.8	-38.6	173.2	179.6	0	0	0	0	114	G80 N84 A85	G80-S82 PolarHBondContact O-N 3.4Å; S82-N84 PolarHBondContact O-N 2.96Å; S82-A85 PolarHBondContact O-N 3.02Å
83	Q	48	Very low	61	Low	145 Å²	145	107 Å²	107	68%	0.678	59%	0.589	S	S	*	*	H	α-helix	trans	-60.4	-35.3	179.2	-73.6	-101.4	-23.9	0	0	111.7	G80 A85 V87	G80-Q83 WeakPolarHBondContact O-CB 3.22Å; G80-Q83 PolarHBondContact O-N 2.89Å; G80-Q83 VanDerWaalsContact O-N 3.12Å; Q83-A85 VanDerWaalsContact C-N 3.34Å; Q83-A85 PolarHBondContact O-N 3.15Å; Q83-V87 WeakPolarHBondContact O-CG2 3.42Å; Q83-V87 PolarHBondContact O-N 3.39Å
84	N	70.9	Confident	63.4	Low	93 Å²	93	105.7 Å²	105.7	50%	0.497	58%	0.578	S	S	.	*	H	α-helix	trans	-67.4	-32	-178.9	-66.4	-53.7	0	0	0	113.1	E81 S82 K88	E81-N84 PolarHBondContact O-N 2.88Å; S82-N84 PolarHBondContact O-N 2.96Å; N84-K88 WeakPolarHBondContact O-CB 3.27Å; N84-K88 WeakPolarHBondContact O-CG 3.46Å; N84-K88 PolarHBondContact O-N 2.87Å; N84-K88 VanDerWaalsContact O-N 3.14Å
85	A	82.4	Confident	66.2	Low	57 Å²	57	102.7 Å²	102.7	47%	0.471	55%	0.548	S	S	.	.	H	α-helix	trans	-68	-49.2	-179.8	0	0	0	0	0	111.3	S82 Q83 V87 K88 S89	S82-A85 PolarHBondContact O-N 3.02Å; Q83-A85 VanDerWaalsContact C-N 3.34Å; Q83-A85 PolarHBondContact O-N 3.15Å; A85-V87 PolarHBondContact O-N 3.32Å; A85-K88 PolarHBondContact O-N 3.4Å; A85-S89 PolarHBondContact O-N 2.93Å; A85-S89 PolarHBondContact O-OG 3.14Å
86	T	86.6	Confident	69	Low	85 Å²	85	96.7 Å²	96.7	52%	0.521	53%	0.528	S	S	.	.	H	α-helix	trans	-60.4	-45	179.5	-54.9	0	0	0	0	111.8	K88 S89 L90	T86-K88 PolarHBondContact O-N 3.37Å; T86-S89 PolarHBondContact O-N 2.93Å; T86-L90 HydrophobicContact CG2-CD1 4.17Å; T86-L90 WeakPolarHBondContact O-CG 3.49Å; T86-L90 PolarHBondContact O-N 2.89Å
87	V	83.9	Confident	71.6	Confident	78 Å²	78	93.7 Å²	93.7	47%	0.473	52%	0.515	S	S	.	.	H	α-helix	trans	-62	-43.4	177.2	174.7	0	0	0	0	111.3	Q83 A85 L90 L91	Q83-V87 WeakPolarHBondContact O-CG2 3.42Å; Q83-V87 PolarHBondContact O-N 3.39Å; A85-V87 PolarHBondContact O-N 3.32Å; V87-L90 PolarHBondContact O-N 3.38Å; V87-L91 HydrophobicContact CG1-CD1 4.25Å; V87-L91 HydrophobicContact CG1-CG 4.49Å; V87-L91 VanDerWaalsContact O-CG 3.31Å; V87-L91 WeakPolarHBondContact O-CG 3.46Å; V87-L91 PolarHBondContact O-N 2.93Å
88	K	86.6	Confident	74	Confident	80 Å²	80	83 Å²	83	35%	0.348	48%	0.475	S	S	.	.	H	α-helix	trans	-63.1	-42.4	176.8	-73.1	176.5	-172.3	-148.9	0	112.5	N84 A85 T86 L91 V92 V150	N84-K88 WeakPolarHBondContact O-CB 3.27Å; N84-K88 WeakPolarHBondContact O-CG 3.46Å; N84-K88 PolarHBondContact O-N 2.87Å; N84-K88 VanDerWaalsContact O-N 3.14Å; A85-K88 PolarHBondContact O-N 3.4Å; T86-K88 PolarHBondContact O-N 3.37Å; K88-L91 WeakPolarHBondContact O-CB 3.35Å; K88-L91 PolarHBondContact O-N 2.91Å; K88-V92 WeakPolarHBondContact O-CG2 3.42Å; K88-V92 PolarHBondContact O-N 2.93Å; K88-V150 HydrophobicContact CB-CG1 4.34Å; K88-V150 HydrophobicContact CD-CG1 4.26Å; K88-V150 WeakPolarHBondContact CD-O 3.39Å; K88-V150 WeakPolarHBondContact CE-O 3.32Å; K88-V150 HydrophobicContact CG-CG1 4.28Å; K88-V150 PolarHBondContact NZ-O 3.27Å
89	S	89.2	Confident	76.9	Confident	74 Å²	74	72.9 Å²	72.9	52%	0.517	44%	0.437	S	S	.	.	H	α-helix	trans	-61.7	-43.9	175	-65.2	0	0	0	0	112	A85 T86 L91 V92 V93	A85-S89 PolarHBondContact O-N 2.93Å; A85-S89 PolarHBondContact O-OG 3.14Å; T86-S89 PolarHBondContact O-N 2.93Å; S89-L91 PolarHBondContact O-N 3.33Å; S89-V92 PolarHBondContact O-N 3.09Å; S89-V93 WeakPolarHBondContact O-CG2 3.45Å; S89-V93 PolarHBondContact O-N 3.45Å
90	L	89.3	Confident	79.9	Confident	113 Å²	113	73.9 Å²	73.9	59%	0.592	43%	0.427	S	S	*	.	H	α-helix	trans	-61.3	-43.5	175.3	-71.5	169.9	0	0	0	112	T86 V87 V92 V93 A94	T86-L90 HydrophobicContact CG2-CD1 4.17Å; T86-L90 WeakPolarHBondContact O-CG 3.49Å; T86-L90 PolarHBondContact O-N 2.89Å; V87-L90 PolarHBondContact O-N 3.38Å; L90-V92 PolarHBondContact O-N 3.44Å; L90-V93 PolarHBondContact O-N 3.4Å; L90-A94 WeakPolarHBondContact O-CB 3.35Å; L90-A94 PolarHBondContact O-N 3.41Å
91	L	86.9	Confident	82.8	Confident	18 Å²	18	72.5 Å²	72.5	9%	0.094	41%	0.41	C	S	.	.	H	α-helix	trans	-57.6	-48.2	174.3	-71.1	170.2	0	0	0	111.7	V87 K88 S89 A94 Y95 L146 F149 V150 F345	V87-L91 HydrophobicContact CG1-CD1 4.25Å; V87-L91 HydrophobicContact CG1-CG 4.49Å; V87-L91 VanDerWaalsContact O-CG 3.31Å; V87-L91 WeakPolarHBondContact O-CG 3.46Å; V87-L91 PolarHBondContact O-N 2.93Å; K88-L91 WeakPolarHBondContact O-CB 3.35Å; K88-L91 PolarHBondContact O-N 2.91Å; S89-L91 PolarHBondContact O-N 3.33Å; L91-A94 PolarHBondContact O-N 3.35Å; L91-Y95 WeakPolarHBondContact O-CD2 3.33Å; L91-Y95 PolarHBondContact O-N 3.45Å; L91-L146 HydrophobicContact CB-CD1 4.17Å; L91-F149 HydrophobicContact CD1-CB 4.24Å; L91-V150 HydrophobicContact CB-CG2 4.24Å; L91-F345 HydrophobicContact CD2-CD1 4.1Å; L91-F345 HydrophobicContact CD2-CD2 3.37Å; L91-F345 HydrophobicContact CD2-CE1 4.01Å; L91-F345 HydrophobicContact CD2-CE2 3.28Å; L91-F345 HydrophobicContact CD2-CG 3.8Å; L91-F345 HydrophobicContact CD2-CZ 3.62Å
92	V	92	Very high	85.3	Confident	60 Å²	60	64.1 Å²	64.1	36%	0.364	37%	0.37	S	S	.	.	H	α-helix	trans	-61.5	-48.4	179.7	171.9	0	0	0	0	111.4	K88 S89 L90 S96 L146 V150	K88-V92 WeakPolarHBondContact O-CG2 3.42Å; K88-V92 PolarHBondContact O-N 2.93Å; S89-V92 PolarHBondContact O-N 3.09Å; L90-V92 PolarHBondContact O-N 3.44Å; V92-S96 WeakPolarHBondContact O-CB 3.46Å; V92-S96 PolarHBondContact O-N 3.42Å; V92-S96 PolarHBondContact O-OG 3Å; V92-L146 HydrophobicContact CG2-CD1 4.17Å; V92-V150 HydrophobicContact CG2-CG2 3.83Å
93	V	93.3	Very high	88	Confident	98 Å²	98	61.6 Å²	61.6	59%	0.594	35%	0.349	S	S	*	.	H	α-helix	trans	-61.5	-47.7	178.4	173.6	0	0	0	0	110.6	S89 L90 Y95 S96 F97	S89-V93 WeakPolarHBondContact O-CG2 3.45Å; S89-V93 PolarHBondContact O-N 3.45Å; L90-V93 PolarHBondContact O-N 3.4Å; V93-Y95 PolarHBondContact O-N 3.08Å; V93-S96 PolarHBondContact O-N 3.08Å; V93-F97 WeakPolarHBondContact O-CB 3.42Å; V93-F97 PolarHBondContact O-N 3.08Å
94	A	90.4	Very high	90.1	Very high	24 Å²	24	57.5 Å²	57.5	20%	0.198	33%	0.329	C	S	.	.	H	α-helix	trans	-67.9	-35.7	-174.4	0	0	0	0	0	113.3	L90 L91 W349	L90-A94 WeakPolarHBondContact O-CB 3.35Å; L90-A94 PolarHBondContact O-N 3.41Å; L91-A94 PolarHBondContact O-N 3.35Å; A94-W349 PolarHBondContact O-NE1 3.24Å
95	Y	90.4	Very high	91.1	Very high	0 Å²	0	53.1 Å²	53.1	0%	0	31%	0.306	C	S	.	.	H	α-helix	trans	-77.6	-40.9	172	-86.7	-82.8	0	0	0	112.6	L91 V93 F97 I98 I99 M142 L146 F149 F345 H348 M352	L91-Y95 WeakPolarHBondContact O-CD2 3.33Å; L91-Y95 PolarHBondContact O-N 3.45Å; V93-Y95 PolarHBondContact O-N 3.08Å; Y95-F97 VanDerWaalsContact C-N 3.26Å; Y95-F97 PolarHBondContact O-N 3.06Å; Y95-I98 PolarHBondContact O-N 3.2Å; Y95-I98 VanDerWaalsContact O-N 3.16Å; Y95-I99 VanDerWaalsContact O-CG1 3.31Å; Y95-I99 WeakPolarHBondContact O-CG1 3.29Å; Y95-I99 PolarHBondContact O-N 3.28Å; Y95-M142 HydrophobicContact CD1-CB 4.49Å; Y95-L146 HydrophobicContact CD2-CB 4.31Å; Y95-L146 HydrophobicContact CD2-CD1 3.85Å; Y95-L146 HydrophobicContact CG-CB 4.1Å; Y95-L146 HydrophobicContact CG-CD1 4.2Å; Y95-F149 HydrophobicContact CE2-CD2 4.24Å; Y95-F149 HydrophobicContact CE2-CE2 4.4Å; Y95-F149 WeakPolarHBondContact OH-CE2 3.35Å; Y95-F345 HydrophobicContact CD2-CE2 4.38Å; Y95-F345 AromaticContact CE2-CD2 3.96Å; Y95-F345 HydrophobicContact CE2-CD2 3.96Å; Y95-F345 AromaticContact CE2-CE2 3.65Å; Y95-F345 HydrophobicContact CE2-CE2 3.65Å; Y95-H348 PolarHBondContact OH-CD2 3.48Å; Y95-M352 HydrophobicContact CE1-CG 4.32Å
96	S	94.3	Very high	91.7	Very high	50 Å²	50	50.4 Å²	50.4	35%	0.35	28%	0.283	S	S	.	.	H	α-helix	trans	-61.1	-36.7	178.6	-60.3	0	0	0	0	111.9	V92 V93 I99 V100	V92-S96 WeakPolarHBondContact O-CB 3.46Å; V92-S96 PolarHBondContact O-N 3.42Å; V92-S96 PolarHBondContact O-OG 3Å; V93-S96 PolarHBondContact O-N 3.08Å; S96-I99 PolarHBondContact O-N 2.86Å; S96-V100 WeakPolarHBondContact O-CB 3.5Å; S96-V100 VanDerWaalsContact O-CG2 3.32Å; S96-V100 WeakPolarHBondContact O-CG2 3.37Å; S96-V100 PolarHBondContact O-N 3.24Å
97	F	93.1	Very high	92	Very high	131 Å²	131	50.2 Å²	50.2	58%	0.575	28%	0.282	S	S	*	.	H	α-helix	trans	-59.6	-48.8	173.1	-178.4	-99.3	0	0	0	112.2	V93 Y95 I101	V93-F97 WeakPolarHBondContact O-CB 3.42Å; V93-F97 PolarHBondContact O-N 3.08Å; Y95-F97 VanDerWaalsContact C-N 3.26Å; Y95-F97 PolarHBondContact O-N 3.06Å; F97-I101 HydrophobicContact CD1-CD1 4.01Å; F97-I101 HydrophobicContact CD2-CD1 3.96Å; F97-I101 HydrophobicContact CE1-CD1 3.61Å; F97-I101 HydrophobicContact CE2-CD1 3.55Å; F97-I101 HydrophobicContact CG-CD1 4.19Å; F97-I101 HydrophobicContact CZ-CD1 3.37Å; F97-I101 WeakPolarHBondContact O-CB 3.49Å; F97-I101 WeakPolarHBondContact O-CG1 3.33Å; F97-I101 PolarHBondContact O-N 3.4Å; F97-I101 VanDerWaalsContact O-N 3.15Å
98	I	94.5	Very high	92.3	Very high	2 Å²	2	47.5 Å²	47.5	1%	0.01	27%	0.265	C	S	.	.	H	α-helix	trans	-61.4	-49.1	175.4	-68.6	175.7	0	0	0	110.6	Y95 V100 I101 S102 M142 W349 M352 C356	Y95-I98 PolarHBondContact O-N 3.2Å; Y95-I98 VanDerWaalsContact O-N 3.16Å; I98-V100 PolarHBondContact O-N 3.08Å; I98-I101 PolarHBondContact O-N 3.02Å; I98-S102 VanDerWaalsContact O-CB 3.28Å; I98-S102 WeakPolarHBondContact O-CB 3.27Å; I98-S102 PolarHBondContact O-N 3.14Å; I98-M142 HydrophobicContact CG2-CE 3.81Å; I98-M142 HydrophobicContact CG2-SD 3.54Å; I98-M142 VanDerWaalsContact CG2-SD 3.54Å; I98-W349 HydrophobicContact CD1-CD2 4.1Å; I98-W349 HydrophobicContact CD1-CG 4.16Å; I98-W349 HydrophobicContact CD1-CZ2 4.06Å; I98-W349 HydrophobicContact CG1-CZ2 4.46Å; I98-M352 HydrophobicContact CD1-CB 4.36Å; I98-C356 PolarHBondContact O-SG 3.27Å; I98-C356 VanDerWaalsContact O-SG 3.39Å
99	I	95.4	Very high	92.5	Very high	29 Å²	29	43.7 Å²	43.7	15%	0.149	25%	0.248	C	C	.	.	H	α-helix	trans	-59	-48.5	-176.3	-69.1	164.9	0	0	0	110.9	Y95 S96 I101 L103 T138 M142 P143	Y95-I99 VanDerWaalsContact O-CG1 3.31Å; Y95-I99 WeakPolarHBondContact O-CG1 3.29Å; Y95-I99 PolarHBondContact O-N 3.28Å; S96-I99 PolarHBondContact O-N 2.86Å; I99-I101 PolarHBondContact O-N 3.47Å; I99-L103 HydrophobicContact CG2-CD1 3.86Å; I99-L103 HydrophobicContact CG2-CG 4.43Å; I99-L103 WeakPolarHBondContact O-CB 3.38Å; I99-L103 VanDerWaalsContact O-CG 3.24Å; I99-L103 WeakPolarHBondContact O-CG 3.34Å; I99-L103 PolarHBondContact O-N 3.32Å; I99-T138 HydrophobicContact CB-CG2 4.14Å; I99-T138 HydrophobicContact CG1-CG2 4.1Å; I99-T138 HydrophobicContact CG2-CG2 4.05Å; I99-M142 HydrophobicContact CD1-CB 3.95Å; I99-M142 HydrophobicContact CG1-CB 3.85Å; I99-M142 HydrophobicContact CG1-SD 3.92Å; I99-P143 HydrophobicContact CD1-CB 4.41Å
100	V	95.5	Very high	92.6	Very high	99 Å²	99	41 Å²	41	60%	0.6	23%	0.229	S	C	*	.	H	α-helix	trans	-63.5	-43.3	179.9	171.1	0	0	0	0	111.7	S96 I98 F104	S96-V100 WeakPolarHBondContact O-CB 3.5Å; S96-V100 VanDerWaalsContact O-CG2 3.32Å; S96-V100 WeakPolarHBondContact O-CG2 3.37Å; S96-V100 PolarHBondContact O-N 3.24Å; I98-V100 PolarHBondContact O-N 3.08Å; V100-F104 WeakPolarHBondContact O-CB 3.45Å; V100-F104 PolarHBondContact O-N 2.8Å; V100-F104 VanDerWaalsContact O-N 3.12Å
101	I	94.1	Very high	92.6	Very high	13 Å²	13	40.2 Å²	40.2	7%	0.067	22%	0.222	C	C	.	.	H	α-helix	trans	-71.9	-45.2	-177.3	-70.8	176.6	0	0	0	111.8	W7 F97 I98 I99 G105 C356 F360	W7-I101 HydrophobicContact CH2-CG2 3.98Å; W7-I101 HydrophobicContact CZ2-CB 4.23Å; W7-I101 HydrophobicContact CZ2-CD1 4.07Å; W7-I101 HydrophobicContact CZ2-CG1 3.76Å; W7-I101 HydrophobicContact CZ2-CG2 3.69Å; F97-I101 HydrophobicContact CD1-CD1 4.01Å; F97-I101 HydrophobicContact CD2-CD1 3.96Å; F97-I101 HydrophobicContact CE1-CD1 3.61Å; F97-I101 HydrophobicContact CE2-CD1 3.55Å; F97-I101 HydrophobicContact CG-CD1 4.19Å; F97-I101 HydrophobicContact CZ-CD1 3.37Å; F97-I101 WeakPolarHBondContact O-CB 3.49Å; F97-I101 WeakPolarHBondContact O-CG1 3.33Å; F97-I101 PolarHBondContact O-N 3.4Å; F97-I101 VanDerWaalsContact O-N 3.15Å; I98-I101 PolarHBondContact O-N 3.02Å; I99-I101 PolarHBondContact O-N 3.47Å; I101-G105 PolarHBondContact O-N 3.27Å; I101-C356 HydrophobicContact CG2-CB 3.73Å; I101-F360 HydrophobicContact CG2-CE2 3.87Å; I101-F360 HydrophobicContact CG2-CZ 4.31Å
102	S	95.3	Very high	92.5	Very high	0 Å²	0	39.3 Å²	39.3	0%	0	22%	0.218	C	C	.	.	H	α-helix	trans	-61.7	-52.1	177.6	170.5	0	0	0	0	111.4	I98 F104 G105 N106 T138 T355	I98-S102 VanDerWaalsContact O-CB 3.28Å; I98-S102 WeakPolarHBondContact O-CB 3.27Å; I98-S102 PolarHBondContact O-N 3.14Å; S102-F104 PolarHBondContact O-N 3.39Å; S102-G105 PolarHBondContact O-N 3.25Å; S102-N106 VanDerWaalsContact O-CB 3.29Å; S102-N106 WeakPolarHBondContact O-CB 3.47Å; S102-N106 PolarHBondContact O-N 2.83Å; S102-N106 PolarHBondContact O-ND2 2.97Å; S102-N106 VanDerWaalsContact O-ND2 3.12Å; S102-N106 PolarHBondContact OG-ND2 3.37Å; S102-T138 PolarHBondContact OG-OG1 3.06Å; S102-T355 WeakPolarHBondContact CB-OG1 3.21Å; S102-T355 WeakPolarHBondContact OG-CB 3.47Å; S102-T355 PolarHBondContact OG-OG1 3.33Å
103	L	95.8	Very high	92.3	Very high	44 Å²	44	36.6 Å²	36.6	23%	0.23	20%	0.201	C	C	.	.	H	α-helix	trans	-60.1	-46.2	-179.8	-67.5	178.9	0	0	0	111.5	I99 T107 I135 T138 L139	I99-L103 HydrophobicContact CG2-CD1 3.86Å; I99-L103 HydrophobicContact CG2-CG 4.43Å; I99-L103 WeakPolarHBondContact O-CB 3.38Å; I99-L103 VanDerWaalsContact O-CG 3.24Å; I99-L103 WeakPolarHBondContact O-CG 3.34Å; I99-L103 PolarHBondContact O-N 3.32Å; L103-T107 WeakPolarHBondContact O-CB 3.42Å; L103-T107 PolarHBondContact O-N 2.99Å; L103-T107 VanDerWaalsContact O-N 3.09Å; L103-T107 PolarHBondContact O-OG1 3.41Å; L103-I135 HydrophobicContact CD2-CG2 4.21Å; L103-T138 HydrophobicContact CD1-CG2 4.38Å; L103-T138 HydrophobicContact CD2-CG2 3.72Å; L103-T138 HydrophobicContact CG-CG2 3.65Å; L103-L139 HydrophobicContact CD1-CD2 3.84Å; L103-L139 HydrophobicContact CD2-CD2 3.66Å; L103-L139 HydrophobicContact CD2-CG 3.78Å; L103-L139 HydrophobicContact CG-CD2 4.41Å
104	F	91.8	Very high	92	Very high	60 Å²	60	36.8 Å²	36.8	26%	0.263	20%	0.198	S	C	.	.	H	α-helix	trans	-64.9	-50	180	179.5	-101.3	0	0	0	112	A4 W7 L8 V100 S102 L108	A4-F104 HydrophobicContact CB-CD2 4.28Å; A4-F104 HydrophobicContact CB-CE2 3.51Å; A4-F104 HydrophobicContact CB-CZ 3.89Å; W7-F104 HydrophobicContact CD2-CD1 4.48Å; W7-F104 AromaticContact CE3-CD1 3.58Å; W7-F104 HydrophobicContact CE3-CD1 3.58Å; W7-F104 AromaticContact CE3-CE1 3.55Å; W7-F104 HydrophobicContact CE3-CE1 3.55Å; W7-F104 HydrophobicContact CH2-CD1 4.45Å; W7-F104 AromaticContact CZ3-CD1 3.56Å; W7-F104 HydrophobicContact CZ3-CD1 3.56Å; W7-F104 AromaticContact CZ3-CE1 3.75Å; W7-F104 HydrophobicContact CZ3-CE1 3.75Å; L8-F104 HydrophobicContact CD1-CZ 4Å; L8-F104 HydrophobicContact CD2-CE1 3.72Å; L8-F104 HydrophobicContact CD2-CZ 3.86Å; L8-F104 HydrophobicContact CG-CE1 3.92Å; L8-F104 HydrophobicContact CG-CZ 3.7Å; V100-F104 WeakPolarHBondContact O-CB 3.45Å; V100-F104 PolarHBondContact O-N 2.8Å; V100-F104 VanDerWaalsContact O-N 3.12Å; S102-F104 PolarHBondContact O-N 3.39Å; F104-L108 HydrophobicContact CE1-CD2 4.44Å; F104-L108 WeakPolarHBondContact O-CB 3.48Å; F104-L108 PolarHBondContact O-N 3.16Å
105	G	91.6	Very high	91.7	Very high	0 Å²	0	39.8 Å²	39.8	0%	0	21%	0.206	C	C	.	.	H	α-helix	trans	-67	-43.6	-176	0	0	0	0	0	113	I101 S102 L108 V109 P359	I101-G105 PolarHBondContact O-N 3.27Å; S102-G105 PolarHBondContact O-N 3.25Å; G105-L108 WeakPolarHBondContact O-CB 3.45Å; G105-L108 PolarHBondContact O-N 2.98Å; G105-V109 WeakPolarHBondContact O-CG2 3.42Å; G105-V109 PolarHBondContact O-N 3.29Å; G105-P359 WeakPolarHBondContact O-CG 3.49Å
106	N	94.9	Very high	91.1	Very high	1 Å²	1	40.9 Å²	40.9	1%	0.005	21%	0.212	C	C	.	.	H	α-helix	trans	-74.8	-33.5	-179.6	-69.7	-51.5	0	0	0	112.1	S102 L108 V109 C110 A131 D134 I135 T355 P359	S102-N106 VanDerWaalsContact O-CB 3.29Å; S102-N106 WeakPolarHBondContact O-CB 3.47Å; S102-N106 PolarHBondContact O-N 2.83Å; S102-N106 PolarHBondContact O-ND2 2.97Å; S102-N106 VanDerWaalsContact O-ND2 3.12Å; S102-N106 PolarHBondContact OG-ND2 3.37Å; N106-L108 VanDerWaalsContact C-N 3.31Å; N106-L108 PolarHBondContact O-N 3.24Å; N106-V109 PolarHBondContact O-N 2.98Å; N106-C110 PolarHBondContact O-N 3.32Å; N106-A131 HydrophobicContact CB-CB 3.98Å; N106-D134 WeakPolarHBondContact ND2-CB 3.39Å; N106-I135 HydrophobicContact CB-CD1 4Å; N106-I135 HydrophobicContact CB-CG1 3.78Å; N106-T355 PolarHBondContact ND2-O 2.77Å; N106-P359 WeakPolarHBondContact OD1-CG 3.44Å
107	T	93.3	Very high	90	Very high	81 Å²	81	47 Å²	47	50%	0.497	23%	0.232	S	C	.	.	H	α-helix	trans	-61.9	-40.8	169	-59.2	0	0	0	0	111.3	L103 C110 H111	L103-T107 WeakPolarHBondContact O-CB 3.42Å; L103-T107 PolarHBondContact O-N 2.99Å; L103-T107 VanDerWaalsContact O-N 3.09Å; L103-T107 PolarHBondContact O-OG1 3.41Å; T107-C110 PolarHBondContact O-N 2.98Å; T107-H111 WeakPolarHBondContact O-CB 3.2Å; T107-H111 PolarHBondContact O-N 3.43Å
108	L	89.8	Confident	88.6	Confident	20 Å²	20	52.5 Å²	52.5	11%	0.105	25%	0.249	C	C	.	.	H	α-helix	trans	-63.2	-41	174.3	177.5	72.7	0	0	0	112	L8 F104 G105 N106 H111 V112 F369 L373 L376	L8-L108 HydrophobicContact CD2-CD2 3.68Å; F104-L108 HydrophobicContact CE1-CD2 4.44Å; F104-L108 WeakPolarHBondContact O-CB 3.48Å; F104-L108 PolarHBondContact O-N 3.16Å; G105-L108 WeakPolarHBondContact O-CB 3.45Å; G105-L108 PolarHBondContact O-N 2.98Å; N106-L108 VanDerWaalsContact C-N 3.31Å; N106-L108 PolarHBondContact O-N 3.24Å; L108-H111 PolarHBondContact O-N 3.48Å; L108-V112 HydrophobicContact CD1-CG2 4.16Å; L108-V112 HydrophobicContact CG-CG2 4.41Å; L108-V112 WeakPolarHBondContact O-CB 3.47Å; L108-V112 WeakPolarHBondContact O-CG2 3.33Å; L108-V112 PolarHBondContact O-N 3.44Å; L108-F369 HydrophobicContact CG-CZ 4.42Å; L108-L373 HydrophobicContact CD1-CD1 3.8Å; L108-L373 HydrophobicContact CD2-CD1 3.85Å; L108-L373 HydrophobicContact CG-CD1 4.28Å; L108-L376 HydrophobicContact CD1-CD1 4.22Å
109	V	91.1	Very high	87.3	Confident	0 Å²	0	53.7 Å²	53.7	0%	0	26%	0.255	C	S	.	.	H	α-helix	trans	-59.3	-50.4	175	169	0	0	0	0	110.8	G105 N106 H111 V112 V113 I127 A131 P359 Y362 F369	G105-V109 WeakPolarHBondContact O-CG2 3.42Å; G105-V109 PolarHBondContact O-N 3.29Å; N106-V109 PolarHBondContact O-N 2.98Å; V109-H111 PolarHBondContact O-N 3.47Å; V109-V112 PolarHBondContact O-N 2.92Å; V109-V113 HydrophobicContact CG1-CG2 4.47Å; V109-V113 WeakPolarHBondContact O-CB 3.48Å; V109-V113 VanDerWaalsContact O-CG2 3.29Å; V109-V113 WeakPolarHBondContact O-CG2 3.27Å; V109-V113 PolarHBondContact O-N 3.18Å; V109-I127 HydrophobicContact CG1-CG2 3.64Å; V109-A131 HydrophobicContact CB-CB 4.27Å; V109-A131 HydrophobicContact CG1-CB 4.01Å; V109-P359 HydrophobicContact CG2-CB 4.08Å; V109-P359 HydrophobicContact CG2-CG 4.03Å; V109-Y362 HydrophobicContact CG1-CD2 4.27Å; V109-Y362 HydrophobicContact CG1-CE2 4.28Å; V109-Y362 HydrophobicContact CG2-CD2 3.9Å; V109-Y362 HydrophobicContact CG2-CE2 4.44Å; V109-F369 HydrophobicContact CB-CE2 4.41Å; V109-F369 HydrophobicContact CB-CZ 4.46Å; V109-F369 HydrophobicContact CG2-CE2 4.05Å; V109-F369 HydrophobicContact CG2-CZ 3.83Å
110	C	91.9	Very high	86.2	Confident	18 Å²	18	57.6 Å²	57.6	12%	0.122	27%	0.273	C	S	.	.	H	α-helix	trans	-56	-50.1	174.6	-70.8	0	0	0	0	111.7	N106 T107 V112 V113 I114 A131	N106-C110 PolarHBondContact O-N 3.32Å; T107-C110 PolarHBondContact O-N 2.98Å; C110-V112 PolarHBondContact O-N 3.23Å; C110-V113 PolarHBondContact O-N 3.01Å; C110-I114 HydrophobicContact CB-CD1 4.44Å; C110-I114 VanDerWaalsContact O-CB 3.32Å; C110-I114 WeakPolarHBondContact O-CB 3.4Å; C110-I114 WeakPolarHBondContact O-CD1 3.43Å; C110-I114 WeakPolarHBondContact O-CG1 3.43Å; C110-I114 PolarHBondContact O-N 3.4Å; C110-A131 VanDerWaalsContact SG-CB 3.6Å
111	H	88.8	Confident	85.5	Confident	96 Å²	96	55.2 Å²	55.2	44%	0.444	26%	0.26	S	S	.	.	H	α-helix	trans	-59.2	-48.1	-179.2	-178.4	82.6	0	0	0	112.9	T107 L108 V109 K115	T107-H111 WeakPolarHBondContact O-CB 3.2Å; T107-H111 PolarHBondContact O-N 3.43Å; L108-H111 PolarHBondContact O-N 3.48Å; V109-H111 PolarHBondContact O-N 3.47Å; H111-K115 WeakPolarHBondContact O-CB 3.27Å; H111-K115 PolarHBondContact O-N 3.29Å
112	V	86.1	Confident	84.9	Confident	0 Å²	0	54.8 Å²	54.8	0%	0	26%	0.259	C	S	.	.	H	α-helix	trans	-64.2	-44	-179.1	168.7	0	0	0	0	111.6	L108 V109 C110 N116 F369 E372 L376	L108-V112 HydrophobicContact CD1-CG2 4.16Å; L108-V112 HydrophobicContact CG-CG2 4.41Å; L108-V112 WeakPolarHBondContact O-CB 3.47Å; L108-V112 WeakPolarHBondContact O-CG2 3.33Å; L108-V112 PolarHBondContact O-N 3.44Å; V109-V112 PolarHBondContact O-N 2.92Å; C110-V112 PolarHBondContact O-N 3.23Å; V112-N116 WeakPolarHBondContact O-CB 3.39Å; V112-N116 PolarHBondContact O-N 2.93Å; V112-N116 VanDerWaalsContact O-N 3.12Å; V112-F369 HydrophobicContact CB-CD2 4.13Å; V112-F369 HydrophobicContact CB-CE2 3.65Å; V112-F369 HydrophobicContact CB-CZ 4.05Å; V112-F369 HydrophobicContact CG1-CD2 3.52Å; V112-F369 HydrophobicContact CG1-CE2 3.59Å; V112-F369 HydrophobicContact CG1-CG 4.12Å; V112-F369 HydrophobicContact CG1-CZ 4.25Å; V112-F369 HydrophobicContact CG2-CE2 4.16Å; V112-F369 HydrophobicContact CG2-CZ 4.05Å; V112-E372 HydrophobicContact CG1-CB 3.74Å; V112-E372 HydrophobicContact CG1-CG 4.2Å; V112-L376 HydrophobicContact CG2-CD1 3.71Å
113	V	86.6	Confident	84.4	Confident	2 Å²	2	55.2 Å²	55.2	1%	0.012	26%	0.261	C	S	.	.	H	α-helix	trans	-72.7	-39.9	-177.1	-179.4	0	0	0	0	111.7	V109 C110 M119 H120 I127 I128	V109-V113 HydrophobicContact CG1-CG2 4.47Å; V109-V113 WeakPolarHBondContact O-CB 3.48Å; V109-V113 VanDerWaalsContact O-CG2 3.29Å; V109-V113 WeakPolarHBondContact O-CG2 3.27Å; V109-V113 PolarHBondContact O-N 3.18Å; C110-V113 PolarHBondContact O-N 3.01Å; V113-M119 HydrophobicContact CG2-CE 4.26Å; V113-H120 PolarHBondContact O-CD2 2.67Å; V113-H120 PolarHBondContact O-NE2 3Å; V113-I127 HydrophobicContact CG2-CG2 4.22Å; V113-I128 HydrophobicContact CB-CD1 4.14Å; V113-I128 HydrophobicContact CB-CG1 4.06Å; V113-I128 HydrophobicContact CG1-CD1 3.73Å; V113-I128 HydrophobicContact CG1-CG1 3.9Å
114	I	86.8	Confident	83.9	Confident	102 Å²	102	53.7 Å²	53.7	52%	0.523	25%	0.254	S	S	.	.	H	α-helix	trans	-63.7	-48.9	175.7	-68.7	167.1	0	0	0	110.3	C110 N116 H120 I128	C110-I114 HydrophobicContact CB-CD1 4.44Å; C110-I114 VanDerWaalsContact O-CB 3.32Å; C110-I114 WeakPolarHBondContact O-CB 3.4Å; C110-I114 WeakPolarHBondContact O-CD1 3.43Å; C110-I114 WeakPolarHBondContact O-CG1 3.43Å; C110-I114 PolarHBondContact O-N 3.4Å; I114-N116 PolarHBondContact O-N 3.5Å; I114-H120 PolarHBondContact O-NE2 3.45Å; I114-I128 HydrophobicContact CG1-CD1 3.84Å
115	K	83.6	Confident	83.9	Confident	88 Å²	88	53.5 Å²	53.5	38%	0.383	26%	0.256	S	S	.	.	H	α-helix	trans	-62.6	-41.1	-177.7	-172.8	-169.3	175.3	-151.9	0	112.5	H111 K117 E372	H111-K115 WeakPolarHBondContact O-CB 3.27Å; H111-K115 PolarHBondContact O-N 3.29Å; K115-K117 PolarHBondContact O-N 3.5Å; K115-E372 IonicContact NZ-OE2 3.99Å
116	N	78.9	Confident	83.9	Confident	23 Å²	23	53.5 Å²	53.5	12%	0.123	26%	0.256	C	S	.	.			trans	-81.7	86.2	-175.3	-166.6	-19.7	0	0	0	112.3	V112 I114 R118 M119 H120 E372	V112-N116 WeakPolarHBondContact O-CB 3.39Å; V112-N116 PolarHBondContact O-N 2.93Å; V112-N116 VanDerWaalsContact O-N 3.12Å; I114-N116 PolarHBondContact O-N 3.5Å; N116-R118 PolarHBondContact O-N 3.13Å; N116-R118 WeakPolarHBondContact OD1-CB 3.15Å; N116-R118 PolarHBondContact OD1-N 3.39Å; N116-R118 VanDerWaalsContact OD1-N 3.11Å; N116-M119 HydrophobicContact CB-CB 4.24Å; N116-M119 HydrophobicContact CB-CG 4.2Å; N116-M119 HydrophobicContact CB-SD 4.21Å; N116-M119 WeakPolarHBondContact O-CA 3.46Å; N116-M119 WeakPolarHBondContact O-CB 3.39Å; N116-M119 PolarHBondContact O-N 3.3Å; N116-H120 PolarHBondContact O-CD2 3.32Å; N116-H120 VanDerWaalsContact O-CD2 3.25Å; N116-E372 HydrophobicContact CB-CG 4.06Å; N116-E372 VanDerWaalsContact ND2-CG 3.27Å; N116-E372 WeakPolarHBondContact ND2-CG 3.33Å; N116-E372 PolarHBondContact ND2-OE1 3.2Å
117	K	70.4	Confident	83.8	Confident	178 Å²	178	54.2 Å²	54.2	77%	0.774	26%	0.26	S	S	*	.	G	3₁₀ helix	trans	-52.1	-29.3	175.5	-65.6	-171.3	178.4	-174.7	0	113.9	K115 M119 H120	K115-K117 PolarHBondContact O-N 3.5Å; K117-M119 PolarHBondContact O-N 2.93Å; K117-H120 WeakPolarHBondContact O-CB 3.46Å; K117-H120 PolarHBondContact O-N 3Å
118	R	64.4	Low	83.8	Confident	246 Å²	246	52.2 Å²	52.2	93%	0.928	25%	0.246	S	C	*	.	G	3₁₀ helix	trans	-72.3	-13.1	175.7	-67.3	-176.8	172.7	-175.3	-2	113.6	N116	N116-R118 PolarHBondContact O-N 3.13Å; N116-R118 WeakPolarHBondContact OD1-CB 3.15Å; N116-R118 PolarHBondContact OD1-N 3.39Å; N116-R118 VanDerWaalsContact OD1-N 3.11Å
119	M	66.5	Low	84.1	Confident	27 Å²	27	51.8 Å²	51.8	13%	0.133	24%	0.243	C	C	.	.	G	3₁₀ helix	trans	-94.3	-4.6	173	-72.7	-177.8	55.2	0	0	113.3	V113 N116 K117 S121 S124 A368	V113-M119 HydrophobicContact CG2-CE 4.26Å; N116-M119 HydrophobicContact CB-CB 4.24Å; N116-M119 HydrophobicContact CB-CG 4.2Å; N116-M119 HydrophobicContact CB-SD 4.21Å; N116-M119 WeakPolarHBondContact O-CA 3.46Å; N116-M119 WeakPolarHBondContact O-CB 3.39Å; N116-M119 PolarHBondContact O-N 3.3Å; K117-M119 PolarHBondContact O-N 2.93Å; M119-S121 PolarHBondContact O-N 3.43Å; M119-S124 VanDerWaalsContact O-CB 3.26Å; M119-S124 WeakPolarHBondContact O-CB 3.38Å; M119-S124 PolarHBondContact O-OG 2.96Å; M119-A368 HydrophobicContact CG-CB 4.47Å; M119-A368 HydrophobicContact SD-CB 3.84Å
120	H	73.8	Confident	84.2	Confident	112 Å²	112	52 Å²	52	52%	0.519	24%	0.244	S	C	.	.			trans	-66.1	110.1	-176.1	-74	-156.2	0	0	0	111	V113 I114 N116 K117	V113-H120 PolarHBondContact O-CD2 2.67Å; V113-H120 PolarHBondContact O-NE2 3Å; I114-H120 PolarHBondContact O-NE2 3.45Å; N116-H120 PolarHBondContact O-CD2 3.32Å; N116-H120 VanDerWaalsContact O-CD2 3.25Å; K117-H120 WeakPolarHBondContact O-CB 3.46Å; K117-H120 PolarHBondContact O-N 3Å
121	S	80.9	Confident	84.4	Confident	48 Å²	48	51.1 Å²	51.1	34%	0.336	24%	0.239	S	C	.	.	S	Bend	trans	-158.2	163.1	-176.3	75.6	0	0	0	0	109.8	M119 T123 S124 L125	M119-S121 PolarHBondContact O-N 3.43Å; S121-T123 VanDerWaalsContact C-N 3.28Å; S121-T123 PolarHBondContact O-N 3.09Å; S121-S124 WeakPolarHBondContact O-CA 3.13Å; S121-S124 WeakPolarHBondContact O-CB 2.91Å; S121-S124 PolarHBondContact O-N 2.94Å; S121-S124 PolarHBondContact OG-OG 3.14Å; S121-L125 PolarHBondContact O-N 3.22Å
122	A	80.8	Confident	84.8	Confident	5 Å²	5	49.5 Å²	49.5	4%	0.041	24%	0.235	C	C	.	.	H	α-helix	trans	-54.9	-40.9	179.9	0	0	0	0	0	113.1	S124 L125 F126 M198	A122-S124 PolarHBondContact O-N 3.01Å; A122-L125 WeakPolarHBondContact O-CB 3.36Å; A122-L125 PolarHBondContact O-N 3.01Å; A122-F126 WeakPolarHBondContact O-CD2 3.33Å; A122-F126 PolarHBondContact O-N 2.94Å; A122-M198 HydrophobicContact CB-CB 3.86Å; A122-M198 HydrophobicContact CB-CG 3.86Å; A122-M198 HydrophobicContact CB-SD 3.83Å
123	T	83.9	Confident	85.3	Confident	8 Å²	8	49.5 Å²	49.5	5%	0.049	24%	0.235	C	C	.	.	H	α-helix	trans	-66.1	-26.6	176.6	-25.3	0	0	0	0	113.2	S121 F126 I127 I182 D185 R186	S121-T123 VanDerWaalsContact C-N 3.28Å; S121-T123 PolarHBondContact O-N 3.09Å; T123-F126 PolarHBondContact O-N 3.29Å; T123-I127 WeakPolarHBondContact O-CG1 3.2Å; T123-I127 PolarHBondContact O-N 3.42Å; T123-I182 HydrophobicContact CG2-CB 4.42Å; T123-I182 HydrophobicContact CG2-CG1 4.04Å; T123-I182 HydrophobicContact CG2-CG2 3.82Å; T123-D185 PolarHBondContact OG1-OD2 3.43Å; T123-R186 VanDerWaalsContact CB-NH2 3.31Å; T123-R186 VanDerWaalsContact OG1-CZ 3.23Å; T123-R186 PolarHBondContact OG1-NH1 3.15Å; T123-R186 PolarHBondContact OG1-NH2 3.45Å
124	S	86.9	Confident	85.8	Confident	12 Å²	12	49.7 Å²	49.7	8%	0.084	24%	0.236	C	C	.	.	H	α-helix	trans	-76.5	-30.2	178.4	-54.2	0	0	0	0	112	M119 S121 A122 I127 I128	M119-S124 VanDerWaalsContact O-CB 3.26Å; M119-S124 WeakPolarHBondContact O-CB 3.38Å; M119-S124 PolarHBondContact O-OG 2.96Å; S121-S124 WeakPolarHBondContact O-CA 3.13Å; S121-S124 WeakPolarHBondContact O-CB 2.91Å; S121-S124 PolarHBondContact O-N 2.94Å; S121-S124 PolarHBondContact OG-OG 3.14Å; A122-S124 PolarHBondContact O-N 3.01Å; S124-I127 PolarHBondContact O-N 2.91Å; S124-I128 WeakPolarHBondContact O-CG1 3.43Å; S124-I128 PolarHBondContact O-N 3.18Å; S124-I128 VanDerWaalsContact O-N 3.08Å
125	L	90.8	Very high	86.3	Confident	57 Å²	57	46.5 Å²	46.5	30%	0.298	22%	0.22	S	C	.	.	H	α-helix	trans	-62.7	-44.2	167.3	-61.3	174.4	0	0	0	110.5	S121 A122 I127 I128 N129 P200 V204	S121-L125 PolarHBondContact O-N 3.22Å; A122-L125 WeakPolarHBondContact O-CB 3.36Å; A122-L125 PolarHBondContact O-N 3.01Å; L125-I127 VanDerWaalsContact C-N 3.34Å; L125-I127 PolarHBondContact O-N 2.88Å; L125-I128 PolarHBondContact O-N 3.22Å; L125-N129 WeakPolarHBondContact O-CB 3.18Å; L125-N129 PolarHBondContact O-N 3.42Å; L125-P200 HydrophobicContact CD1-CB 4.43Å; L125-P200 WeakPolarHBondContact CD1-O 3.42Å; L125-V204 HydrophobicContact CD1-CG2 3.95Å
126	F	92.6	Very high	86.9	Confident	0 Å²	0	44.6 Å²	44.6	0%	0	21%	0.213	C	C	.	.	H	α-helix	trans	-64.1	-34.4	175.6	-61.8	-40.5	0	0	0	113.4	A122 T123 N129 L130 T178 A181 I182 M198 C206 V207 I210	A122-F126 WeakPolarHBondContact O-CD2 3.33Å; A122-F126 PolarHBondContact O-N 2.94Å; T123-F126 PolarHBondContact O-N 3.29Å; F126-N129 WeakPolarHBondContact O-CB 3.39Å; F126-N129 PolarHBondContact O-N 3.04Å; F126-L130 PolarHBondContact O-N 3.02Å; F126-T178 HydrophobicContact CB-CG2 3.62Å; F126-T178 HydrophobicContact CD1-CG2 4.18Å; F126-T178 HydrophobicContact CG-CG2 4.19Å; F126-T178 VanDerWaalsContact O-CG2 3.31Å; F126-T178 WeakPolarHBondContact O-CG2 3.48Å; F126-A181 HydrophobicContact CD2-CB 4.46Å; F126-A181 HydrophobicContact CE1-CB 4.14Å; F126-A181 HydrophobicContact CE2-CB 4.06Å; F126-A181 HydrophobicContact CZ-CB 3.89Å; F126-I182 HydrophobicContact CB-CD1 3.75Å; F126-I182 HydrophobicContact CB-CG1 3.51Å; F126-I182 HydrophobicContact CD2-CG1 3.84Å; F126-I182 HydrophobicContact CG-CG1 4.01Å; F126-M198 HydrophobicContact CE2-SD 4.1Å; F126-M198 HydrophobicContact CZ-SD 4Å; F126-C206 HydrophobicContact CE1-CB 4.01Å; F126-C206 HydrophobicContact CZ-CB 3.96Å; F126-V207 HydrophobicContact CD1-CG2 3.78Å; F126-V207 HydrophobicContact CE1-CG2 3.86Å; F126-I210 HydrophobicContact CE1-CD1 4.37Å
127	I	91.4	Very high	87.7	Confident	16 Å²	16	43.6 Å²	43.6	8%	0.082	21%	0.208	C	C	.	.	H	α-helix	trans	-66.8	-39.6	173.4	-70.7	164.8	0	0	0	111.6	V109 V113 T123 S124 L125 N129 A131 Y362	V109-I127 HydrophobicContact CG1-CG2 3.64Å; V113-I127 HydrophobicContact CG2-CG2 4.22Å; T123-I127 WeakPolarHBondContact O-CG1 3.2Å; T123-I127 PolarHBondContact O-N 3.42Å; S124-I127 PolarHBondContact O-N 2.91Å; L125-I127 VanDerWaalsContact C-N 3.34Å; L125-I127 PolarHBondContact O-N 2.88Å; I127-N129 VanDerWaalsContact C-N 3.34Å; I127-A131 PolarHBondContact O-N 3.2Å; I127-Y362 HydrophobicContact CG2-CD2 4.37Å; I127-Y362 HydrophobicContact CG2-CE2 3.81Å
128	I	93.1	Very high	89	Confident	39 Å²	39	35.1 Å²	35.1	20%	0.2	17%	0.171	C	C	.	.	H	α-helix	trans	-64.9	-40.4	171.6	-68.8	168.1	0	0	0	110.4	V113 I114 S124 L125 L130 A131 V132	V113-I128 HydrophobicContact CB-CD1 4.14Å; V113-I128 HydrophobicContact CB-CG1 4.06Å; V113-I128 HydrophobicContact CG1-CD1 3.73Å; V113-I128 HydrophobicContact CG1-CG1 3.9Å; I114-I128 HydrophobicContact CG1-CD1 3.84Å; S124-I128 WeakPolarHBondContact O-CG1 3.43Å; S124-I128 PolarHBondContact O-N 3.18Å; S124-I128 VanDerWaalsContact O-N 3.08Å; L125-I128 PolarHBondContact O-N 3.22Å; I128-L130 PolarHBondContact O-N 3.44Å; I128-A131 PolarHBondContact O-N 3.03Å; I128-V132 HydrophobicContact CG2-CG2 4.2Å; I128-V132 WeakPolarHBondContact O-CG2 3.42Å; I128-V132 PolarHBondContact O-N 3.33Å
129	N	95.9	Very high	90.5	Very high	11 Å²	11	27.4 Å²	27.4	6%	0.059	15%	0.148	C	C	.	.	H	α-helix	trans	-61.6	-41.3	-179.6	-160.9	57.1	0	0	0	112.7	L125 F126 I127 V132 A133 V174 T178 V207 W211	L125-N129 WeakPolarHBondContact O-CB 3.18Å; L125-N129 PolarHBondContact O-N 3.42Å; F126-N129 WeakPolarHBondContact O-CB 3.39Å; F126-N129 PolarHBondContact O-N 3.04Å; I127-N129 VanDerWaalsContact C-N 3.34Å; N129-V132 PolarHBondContact O-N 2.99Å; N129-A133 PolarHBondContact O-N 3.36Å; N129-V174 WeakPolarHBondContact ND2-CG1 3.49Å; N129-T178 HydrophobicContact CB-CG2 4.29Å; N129-T178 PolarHBondContact ND2-OG1 2.97Å; N129-V207 HydrophobicContact CB-CG2 4.29Å; N129-V207 WeakPolarHBondContact OD1-CG1 3.21Å; N129-W211 PolarHBondContact OD1-NE1 3.33Å
130	L	94.6	Very high	91.8	Very high	3 Å²	3	29 Å²	29	2%	0.016	16%	0.157	C	C	.	.	H	α-helix	trans	-59.8	-50.7	171.3	-75.9	163.3	0	0	0	111.5	F126 I128 V132 A133 D134 T178 L179 I182	F126-L130 PolarHBondContact O-N 3.02Å; I128-L130 PolarHBondContact O-N 3.44Å; L130-V132 VanDerWaalsContact C-N 3.27Å; L130-V132 PolarHBondContact O-N 3.43Å; L130-A133 PolarHBondContact O-N 3.32Å; L130-A133 VanDerWaalsContact O-N 3.14Å; L130-D134 WeakPolarHBondContact O-CB 3.48Å; L130-D134 PolarHBondContact O-N 3.32Å; L130-T178 HydrophobicContact CD1-CG2 4.23Å; L130-T178 HydrophobicContact CD2-CG2 4.35Å; L130-T178 HydrophobicContact CG-CG2 3.82Å; L130-L179 HydrophobicContact CD1-CD2 3.89Å; L130-L179 HydrophobicContact CD2-CD2 4.34Å; L130-L179 HydrophobicContact CD2-CG 4.21Å; L130-I182 HydrophobicContact CD1-CD1 3.81Å
131	A	95.7	Very high	92.8	Very high	1 Å²	1	23.8 Å²	23.8	1%	0.008	13%	0.133	C	C	.	.	H	α-helix	trans	-61.1	-34.3	179.5	0	0	0	0	0	112.8	N106 V109 C110 I127 I128 I135	N106-A131 HydrophobicContact CB-CB 3.98Å; V109-A131 HydrophobicContact CB-CB 4.27Å; V109-A131 HydrophobicContact CG1-CB 4.01Å; C110-A131 VanDerWaalsContact SG-CB 3.6Å; I127-A131 PolarHBondContact O-N 3.2Å; I128-A131 PolarHBondContact O-N 3.03Å; A131-I135 WeakPolarHBondContact O-CB 3.35Å; A131-I135 WeakPolarHBondContact O-CD1 3.37Å; A131-I135 WeakPolarHBondContact O-CG1 3.15Å; A131-I135 PolarHBondContact O-N 3.33Å
132	V	96.9	Very high	93.3	Very high	62 Å²	62	21.5 Å²	21.5	38%	0.376	12%	0.117	S	C	.	.	H	α-helix	trans	-69	-43.4	173.5	170.9	0	0	0	0	111.7	I128 N129 L130 I135 L136 W211	I128-V132 HydrophobicContact CG2-CG2 4.2Å; I128-V132 WeakPolarHBondContact O-CG2 3.42Å; I128-V132 PolarHBondContact O-N 3.33Å; N129-V132 PolarHBondContact O-N 2.99Å; L130-V132 VanDerWaalsContact C-N 3.27Å; L130-V132 PolarHBondContact O-N 3.43Å; V132-I135 PolarHBondContact O-N 2.93Å; V132-L136 WeakPolarHBondContact O-CB 3.24Å; V132-L136 PolarHBondContact O-N 3.01Å; V132-W211 HydrophobicContact CG1-CZ2 4.19Å
133	A	97.1	Very high	93.9	Very high	0 Å²	0	23.3 Å²	23.3	0%	0	13%	0.128	C	C	.	.	H	α-helix	trans	-63.7	-41.9	176	0	0	0	0	0	112.2	N129 L130 L136 I137 S171 V174	N129-A133 PolarHBondContact O-N 3.36Å; L130-A133 PolarHBondContact O-N 3.32Å; L130-A133 VanDerWaalsContact O-N 3.14Å; A133-L136 PolarHBondContact O-N 2.91Å; A133-I137 PolarHBondContact O-N 3Å; A133-I137 VanDerWaalsContact O-N 3.16Å; A133-S171 WeakPolarHBondContact O-CB 3.37Å; A133-S171 PolarHBondContact O-OG 2.84Å; A133-V174 HydrophobicContact CB-CB 4.25Å; A133-V174 HydrophobicContact CB-CG1 3.84Å
134	D	96.6	Very high	94.2	Very high	5 Å²	5	24.9 Å²	24.9	3%	0.027	14%	0.135	C	C	.	.	H	α-helix	trans	-63.4	-42.4	175.2	-74.5	-20.2	0	0	0	111.8	N106 L130 I137 T138 T355 N358	N106-D134 WeakPolarHBondContact ND2-CB 3.39Å; L130-D134 WeakPolarHBondContact O-CB 3.48Å; L130-D134 PolarHBondContact O-N 3.32Å; D134-I137 WeakPolarHBondContact O-CG2 3.46Å; D134-T138 VanDerWaalsContact O-CB 3.28Å; D134-T138 WeakPolarHBondContact O-CB 3.37Å; D134-T138 PolarHBondContact O-N 3.22Å; D134-T138 VanDerWaalsContact O-N 3.1Å; D134-T138 PolarHBondContact O-OG1 3.33Å; D134-T355 HydrophobicContact CB-CG2 4.13Å; D134-N358 PolarHBondContact OD2-ND2 3.38Å
135	I	97.2	Very high	94.2	Very high	35 Å²	35	24.7 Å²	24.7	18%	0.179	13%	0.133	C	C	.	.	H	α-helix	trans	-63.5	-43.3	174	-72.8	164.7	0	0	0	110.9	L103 N106 A131 V132 I137 T138 L139	L103-I135 HydrophobicContact CD2-CG2 4.21Å; N106-I135 HydrophobicContact CB-CD1 4Å; N106-I135 HydrophobicContact CB-CG1 3.78Å; A131-I135 WeakPolarHBondContact O-CB 3.35Å; A131-I135 WeakPolarHBondContact O-CD1 3.37Å; A131-I135 WeakPolarHBondContact O-CG1 3.15Å; A131-I135 PolarHBondContact O-N 3.33Å; V132-I135 PolarHBondContact O-N 2.93Å; I135-I137 PolarHBondContact O-N 2.63Å; I135-T138 PolarHBondContact O-N 3.09Å; I135-L139 HydrophobicContact CG2-CD1 3.74Å; I135-L139 HydrophobicContact CG2-CG 4.21Å; I135-L139 WeakPolarHBondContact O-CG 3.5Å; I135-L139 PolarHBondContact O-N 2.87Å
136	L	96.8	Very high	94.2	Very high	48 Å²	48	22.8 Å²	22.8	25%	0.251	12%	0.123	S	C	.	.	H	α-helix	trans	-60.7	-47.5	-177.3	-168.9	72.4	0	0	0	111.9	V132 A133 T138 L139 L140 V167 W211	V132-L136 WeakPolarHBondContact O-CB 3.24Å; V132-L136 PolarHBondContact O-N 3.01Å; A133-L136 PolarHBondContact O-N 2.91Å; L136-T138 VanDerWaalsContact C-N 3.34Å; L136-L139 PolarHBondContact O-N 2.7Å; L136-L140 HydrophobicContact CD1-CD1 3.62Å; L136-L140 HydrophobicContact CD1-CG 4.38Å; L136-L140 HydrophobicContact CG-CD1 4.31Å; L136-L140 WeakPolarHBondContact O-CB 3.29Å; L136-L140 PolarHBondContact O-N 2.95Å; L136-V167 HydrophobicContact CB-CG1 4.48Å; L136-V167 HydrophobicContact CD2-CG1 4.14Å; L136-V167 HydrophobicContact CD2-CG2 4.34Å; L136-V167 HydrophobicContact CG-CG1 3.84Å; L136-V167 HydrophobicContact CG-CG2 4.35Å; L136-W211 HydrophobicContact CD2-CH2 3.94Å; L136-W211 HydrophobicContact CD2-CZ3 4.07Å
137	I	95.7	Very high	94	Very high	2 Å²	2	25.1 Å²	25.1	1%	0.01	14%	0.137	C	C	.	.	H	α-helix	trans	-69.9	-32.4	178	-163.6	172	0	0	0	112.3	A133 D134 I135 N141 M142 V167 Q168 W322 M352 T355	A133-I137 PolarHBondContact O-N 3Å; A133-I137 VanDerWaalsContact O-N 3.16Å; D134-I137 WeakPolarHBondContact O-CG2 3.46Å; I135-I137 PolarHBondContact O-N 2.63Å; I137-N141 HydrophobicContact CG1-CB 3.86Å; I137-N141 WeakPolarHBondContact O-CB 3.38Å; I137-N141 PolarHBondContact O-N 3.37Å; I137-N141 VanDerWaalsContact O-N 3.11Å; I137-M142 HydrophobicContact CG2-CE 4.43Å; I137-M142 PolarHBondContact O-N 3.26Å; I137-M142 VanDerWaalsContact O-N 3.08Å; I137-V167 HydrophobicContact CB-CG1 4.19Å; I137-V167 HydrophobicContact CG1-CG1 4.49Å; I137-Q168 HydrophobicContact CD1-CG 4.45Å; I137-W322 HydrophobicContact CD1-CH2 3.91Å; I137-W322 HydrophobicContact CD1-CZ2 4.28Å; I137-M352 HydrophobicContact CD1-CE 3.67Å; I137-M352 HydrophobicContact CD1-SD 4.05Å; I137-M352 HydrophobicContact CG1-CE 4.27Å; I137-M352 HydrophobicContact CG1-SD 4.13Å; I137-T355 HydrophobicContact CG2-CG2 3.84Å
138	T	96.6	Very high	93.6	Very high	0 Å²	0	27.3 Å²	27.3	0%	0	14%	0.144	C	C	.	.	H	α-helix	trans	-68.8	-35.2	175.3	-55.6	0	0	0	0	112.5	I99 S102 L103 D134 I135 L136 M142 P143	I99-T138 HydrophobicContact CB-CG2 4.14Å; I99-T138 HydrophobicContact CG1-CG2 4.1Å; I99-T138 HydrophobicContact CG2-CG2 4.05Å; S102-T138 PolarHBondContact OG-OG1 3.06Å; L103-T138 HydrophobicContact CD1-CG2 4.38Å; L103-T138 HydrophobicContact CD2-CG2 3.72Å; L103-T138 HydrophobicContact CG-CG2 3.65Å; D134-T138 VanDerWaalsContact O-CB 3.28Å; D134-T138 WeakPolarHBondContact O-CB 3.37Å; D134-T138 PolarHBondContact O-N 3.22Å; D134-T138 VanDerWaalsContact O-N 3.1Å; D134-T138 PolarHBondContact O-OG1 3.33Å; I135-T138 PolarHBondContact O-N 3.09Å; L136-T138 VanDerWaalsContact C-N 3.34Å; T138-M142 HydrophobicContact CG2-CE 4.36Å; T138-M142 HydrophobicContact CG2-SD 3.88Å; T138-M142 VanDerWaalsContact OG1-CE 3.31Å; T138-M142 WeakPolarHBondContact OG1-CE 3.16Å; T138-P143 WeakPolarHBondContact O-CD 3.15Å
139	L	96	Very high	93.1	Very high	85 Å²	85	26.7 Å²	26.7	45%	0.445	14%	0.14	S	C	.	.	H	α-helix	trans	-82.3	-46.6	177.2	-68.7	177.6	0	0	0	113.1	L103 I135 L136 P143 F144	L103-L139 HydrophobicContact CD1-CD2 3.84Å; L103-L139 HydrophobicContact CD2-CD2 3.66Å; L103-L139 HydrophobicContact CD2-CG 3.78Å; L103-L139 HydrophobicContact CG-CD2 4.41Å; I135-L139 HydrophobicContact CG2-CD1 3.74Å; I135-L139 HydrophobicContact CG2-CG 4.21Å; I135-L139 WeakPolarHBondContact O-CG 3.5Å; I135-L139 PolarHBondContact O-N 2.87Å; L136-L139 PolarHBondContact O-N 2.7Å; L139-P143 VanDerWaalsContact O-CG 3.25Å; L139-P143 WeakPolarHBondContact O-CG 3.31Å; L139-F144 WeakPolarHBondContact O-CE2 3.17Å
140	L	94.8	Very high	92.6	Very high	60 Å²	60	27.4 Å²	27.4	31%	0.314	15%	0.145	S	C	.	.	H	α-helix	trans	-103	-7.7	-165.6	-56.6	-177.3	0	0	0	115	L136 F144 V167	L136-L140 HydrophobicContact CD1-CD1 3.62Å; L136-L140 HydrophobicContact CD1-CG 4.38Å; L136-L140 HydrophobicContact CG-CD1 4.31Å; L136-L140 WeakPolarHBondContact O-CB 3.29Å; L136-L140 PolarHBondContact O-N 2.95Å; L140-F144 VanDerWaalsContact O-CD2 3.31Å; L140-F144 WeakPolarHBondContact O-CD2 3.39Å; L140-V167 HydrophobicContact CB-CB 4.41Å; L140-V167 HydrophobicContact CB-CG1 4.2Å; L140-V167 HydrophobicContact CB-CG2 4.06Å; L140-V167 HydrophobicContact CD1-CG2 4.06Å
141	N	93.8	Very high	92	Very high	2 Å²	2	31.9 Å²	31.9	1%	0.011	17%	0.169	C	C	.	.	T	Hydrogen-bonded Turn	trans	-120	-49.6	174.8	177.8	73.2	0	0	0	113.6	I137 F144 T145 S164	I137-N141 HydrophobicContact CG1-CB 3.86Å; I137-N141 WeakPolarHBondContact O-CB 3.38Å; I137-N141 PolarHBondContact O-N 3.37Å; I137-N141 VanDerWaalsContact O-N 3.11Å; N141-F144 PolarHBondContact O-N 2.91Å; N141-T145 VanDerWaalsContact O-CB 3.22Å; N141-T145 WeakPolarHBondContact O-CB 3.46Å; N141-T145 PolarHBondContact O-N 3.23Å; N141-T145 PolarHBondContact O-OG1 3.44Å; N141-T145 PolarHBondContact OD1-OG1 2.91Å; N141-S164 PolarHBondContact OD1-O 3.47Å; N141-S164 PolarHBondContact OD1-OG 3.33Å
142	M	93	Very high	91.3	Very high	0 Å²	0	35.1 Å²	35.1	0%	0	19%	0.191	C	C	.	.	H	α-helix	trans	-57.5	-52	-172.7	-67.2	-174.1	-161.9	0	0	115.2	Y95 I98 I99 I137 T138 T145 L146 M352 T355	Y95-M142 HydrophobicContact CD1-CB 4.49Å; I98-M142 HydrophobicContact CG2-CE 3.81Å; I98-M142 HydrophobicContact CG2-SD 3.54Å; I98-M142 VanDerWaalsContact CG2-SD 3.54Å; I99-M142 HydrophobicContact CD1-CB 3.95Å; I99-M142 HydrophobicContact CG1-CB 3.85Å; I99-M142 HydrophobicContact CG1-SD 3.92Å; I137-M142 HydrophobicContact CG2-CE 4.43Å; I137-M142 PolarHBondContact O-N 3.26Å; I137-M142 VanDerWaalsContact O-N 3.08Å; T138-M142 HydrophobicContact CG2-CE 4.36Å; T138-M142 HydrophobicContact CG2-SD 3.88Å; T138-M142 VanDerWaalsContact OG1-CE 3.31Å; T138-M142 WeakPolarHBondContact OG1-CE 3.16Å; M142-T145 PolarHBondContact O-N 2.91Å; M142-L146 WeakPolarHBondContact O-CB 3.19Å; M142-L146 PolarHBondContact O-N 2.94Å; M142-M352 HydrophobicContact CE-CB 3.89Å; M142-M352 HydrophobicContact CE-CG 4.3Å; M142-M352 WeakPolarHBondContact CE-O 3.23Å; M142-M352 HydrophobicContact CE-SD 3.72Å; M142-M352 HydrophobicContact CG-CB 4.5Å; M142-M352 HydrophobicContact CG-CG 4.19Å; M142-M352 HydrophobicContact CG-SD 3.6Å; M142-M352 VanDerWaalsContact CG-SD 3.6Å; M142-M352 HydrophobicContact SD-CB 4.32Å; M142-M352 HydrophobicContact SD-SD 4.36Å; M142-T355 HydrophobicContact CE-CG2 3.76Å
143	P	92.2	Very high	90.4	Very high	44 Å²	44	33.3 Å²	33.3	29%	0.286	18%	0.182	S	C	.	.	H	α-helix	trans	-67.9	-38.2	-177.4	24.8	-33.9	0	0	0	112.6	I99 T138 L139 L146 V147	I99-P143 HydrophobicContact CD1-CB 4.41Å; T138-P143 WeakPolarHBondContact O-CD 3.15Å; L139-P143 VanDerWaalsContact O-CG 3.25Å; L139-P143 WeakPolarHBondContact O-CG 3.31Å; P143-L146 PolarHBondContact O-N 3.46Å; P143-V147 WeakPolarHBondContact O-CG2 3.3Å; P143-V147 PolarHBondContact O-N 3.43Å
144	F	91.2	Very high	89.8	Confident	41 Å²	41	33.7 Å²	33.7	18%	0.18	18%	0.183	C	C	.	.	H	α-helix	trans	-64.7	-41.6	176.5	-59.5	-82.2	0	0	0	111.3	L139 L140 N141 V147 R148 W154 F156 M160	L139-F144 WeakPolarHBondContact O-CE2 3.17Å; L140-F144 VanDerWaalsContact O-CD2 3.31Å; L140-F144 WeakPolarHBondContact O-CD2 3.39Å; N141-F144 PolarHBondContact O-N 2.91Å; F144-V147 PolarHBondContact O-N 2.95Å; F144-R148 WeakPolarHBondContact O-CB 3.45Å; F144-R148 PolarHBondContact O-N 3.31Å; F144-W154 HydrophobicContact CB-CH2 3.84Å; F144-W154 HydrophobicContact CB-CZ3 4.32Å; F144-F156 HydrophobicContact CB-CD2 4.3Å; F144-F156 HydrophobicContact CB-CE2 4.12Å; F144-F156 HydrophobicContact CD1-CB 4.28Å; F144-F156 AromaticContact CD1-CD1 3.64Å; F144-F156 HydrophobicContact CD1-CD1 3.64Å; F144-F156 AromaticContact CD1-CD2 3.72Å; F144-F156 HydrophobicContact CD1-CD2 3.72Å; F144-F156 AromaticContact CD1-CE1 3.74Å; F144-F156 HydrophobicContact CD1-CE1 3.74Å; F144-F156 AromaticContact CD1-CE2 3.81Å; F144-F156 HydrophobicContact CD1-CE2 3.81Å; F144-F156 AromaticContact CD1-CG 3.62Å; F144-F156 HydrophobicContact CD1-CG 3.62Å; F144-F156 AromaticContact CD1-CZ 3.8Å; F144-F156 HydrophobicContact CD1-CZ 3.8Å; F144-F156 AromaticContact CE1-CD1 3.79Å; F144-F156 HydrophobicContact CE1-CD1 3.79Å; F144-F156 AromaticContact CE1-CE1 3.96Å; F144-F156 HydrophobicContact CE1-CE1 3.96Å; F144-F156 HydrophobicContact CE1-CG 4.14Å; F144-F156 HydrophobicContact CE1-CZ 4.45Å; F144-F156 HydrophobicContact CG-CE2 4.45Å; F144-M160 HydrophobicContact CD1-CE 4.05Å; F144-M160 HydrophobicContact CD2-CE 3.95Å; F144-M160 HydrophobicContact CE1-CE 3.81Å; F144-M160 HydrophobicContact CE1-CG 4.28Å; F144-M160 HydrophobicContact CE1-SD 4.48Å; F144-M160 HydrophobicContact CE2-CE 3.71Å; F144-M160 HydrophobicContact CG-CE 4.12Å; F144-M160 HydrophobicContact CZ-CE 3.65Å; F144-M160 HydrophobicContact CZ-SD 4.44Å
145	T	87.1	Confident	89.2	Confident	7 Å²	7	36.7 Å²	36.7	4%	0.043	22%	0.215	C	C	.	.	H	α-helix	trans	-66.7	-41.5	174.7	-67.7	0	0	0	0	112.5	N141 M142 R148 F149	N141-T145 VanDerWaalsContact O-CB 3.22Å; N141-T145 WeakPolarHBondContact O-CB 3.46Å; N141-T145 PolarHBondContact O-N 3.23Å; N141-T145 PolarHBondContact O-OG1 3.44Å; N141-T145 PolarHBondContact OD1-OG1 2.91Å; M142-T145 PolarHBondContact O-N 2.91Å; T145-R148 WeakPolarHBondContact O-CB 3.43Å; T145-R148 PolarHBondContact O-N 3.41Å; T145-F149 HydrophobicContact CG2-CD2 3.71Å; T145-F149 HydrophobicContact CG2-CE2 3.34Å; T145-F149 HydrophobicContact CG2-CZ 4.26Å; T145-F149 WeakPolarHBondContact O-CD2 3.4Å; T145-F149 PolarHBondContact O-N 2.97Å
146	L	89.1	Confident	88.7	Confident	17 Å²	17	38.5 Å²	38.5	9%	0.089	22%	0.222	C	C	.	.	H	α-helix	trans	-56.7	-51.5	173.4	167.6	61.5	0	0	0	111	L91 V92 Y95 M142 P143 R148 F149 V150	L91-L146 HydrophobicContact CB-CD1 4.17Å; V92-L146 HydrophobicContact CG2-CD1 4.17Å; Y95-L146 HydrophobicContact CD2-CB 4.31Å; Y95-L146 HydrophobicContact CD2-CD1 3.85Å; Y95-L146 HydrophobicContact CG-CB 4.1Å; Y95-L146 HydrophobicContact CG-CD1 4.2Å; M142-L146 WeakPolarHBondContact O-CB 3.19Å; M142-L146 PolarHBondContact O-N 2.94Å; P143-L146 PolarHBondContact O-N 3.46Å; L146-R148 VanDerWaalsContact C-N 3.32Å; L146-R148 PolarHBondContact O-N 2.96Å; L146-F149 PolarHBondContact O-N 3.2Å; L146-F149 VanDerWaalsContact O-N 3.13Å; L146-V150 HydrophobicContact CD1-CG2 3.66Å; L146-V150 HydrophobicContact CG-CG2 4.38Å; L146-V150 WeakPolarHBondContact O-CG2 3.43Å; L146-V150 PolarHBondContact O-N 3.48Å
147	V	88.4	Confident	88.2	Confident	50 Å²	50	38 Å²	38	30%	0.303	23%	0.228	S	C	.	.	H	α-helix	trans	-64.1	-38	-179.7	172.6	0	0	0	0	111.3	P143 F144 F149 V150 N151 F156	P143-V147 WeakPolarHBondContact O-CG2 3.3Å; P143-V147 PolarHBondContact O-N 3.43Å; F144-V147 PolarHBondContact O-N 2.95Å; V147-F149 VanDerWaalsContact C-N 3.32Å; V147-F149 PolarHBondContact O-N 3.38Å; V147-V150 PolarHBondContact O-N 3.28Å; V147-N151 WeakPolarHBondContact O-CB 3.36Å; V147-N151 PolarHBondContact O-N 2.92Å; V147-F156 HydrophobicContact CB-CE2 3.81Å; V147-F156 HydrophobicContact CB-CZ 3.65Å; V147-F156 HydrophobicContact CG1-CE2 3.78Å; V147-F156 HydrophobicContact CG1-CZ 3.6Å; V147-F156 HydrophobicContact CG2-CZ 4.06Å
148	R	84.1	Confident	87.9	Confident	61 Å²	61	44.5 Å²	44.5	23%	0.23	26%	0.256	C	S	.	.	H	α-helix	trans	-56.3	-44.1	171.9	-172.9	-167.4	73.5	121.3	6.5	112	F144 T145 L146 S152 S153 W154	F144-R148 WeakPolarHBondContact O-CB 3.45Å; F144-R148 PolarHBondContact O-N 3.31Å; T145-R148 WeakPolarHBondContact O-CB 3.43Å; T145-R148 PolarHBondContact O-N 3.41Å; L146-R148 VanDerWaalsContact C-N 3.32Å; L146-R148 PolarHBondContact O-N 2.96Å; R148-S152 VanDerWaalsContact O-CA 3.22Å; R148-S152 WeakPolarHBondContact O-CA 3.25Å; R148-S152 PolarHBondContact O-N 3.48Å; R148-S153 PolarHBondContact O-N 2.96Å; R148-W154 HydrophobicContact CB-CE3 3.93Å; R148-W154 HydrophobicContact CB-CZ3 4.18Å; R148-W154 HydrophobicContact CG-CE3 3.88Å; R148-W154 HydrophobicContact CG-CZ3 4.45Å
149	F	83.1	Confident	87.5	Confident	27 Å²	27	46.6 Å²	46.6	12%	0.118	28%	0.278	C	S	.	.	H	α-helix	trans	-67.8	-49.4	176.6	-73.5	-59.3	0	0	0	112.1	L91 Y95 T145 L146 V147 N151 S152 Y344 F345	L91-F149 HydrophobicContact CD1-CB 4.24Å; Y95-F149 HydrophobicContact CE2-CD2 4.24Å; Y95-F149 HydrophobicContact CE2-CE2 4.4Å; Y95-F149 WeakPolarHBondContact OH-CE2 3.35Å; T145-F149 HydrophobicContact CG2-CD2 3.71Å; T145-F149 HydrophobicContact CG2-CE2 3.34Å; T145-F149 HydrophobicContact CG2-CZ 4.26Å; T145-F149 WeakPolarHBondContact O-CD2 3.4Å; T145-F149 PolarHBondContact O-N 2.97Å; L146-F149 PolarHBondContact O-N 3.2Å; L146-F149 VanDerWaalsContact O-N 3.13Å; V147-F149 VanDerWaalsContact C-N 3.32Å; V147-F149 PolarHBondContact O-N 3.38Å; F149-N151 PolarHBondContact O-N 3.28Å; F149-S152 PolarHBondContact O-N 2.94Å; F149-S152 PolarHBondContact O-OG 3.44Å; F149-Y344 AromaticContact CE1-CD1 3.98Å; F149-Y344 HydrophobicContact CE1-CD1 3.98Å; F149-Y344 HydrophobicContact CE1-CE1 4.29Å; F149-Y344 AromaticContact CZ-CD1 3.7Å; F149-Y344 HydrophobicContact CZ-CD1 3.7Å; F149-Y344 AromaticContact CZ-CE1 3.72Å; F149-Y344 HydrophobicContact CZ-CE1 3.72Å; F149-F345 HydrophobicContact CZ-CB 4.45Å
150	V	85.7	Confident	87.2	Confident	25 Å²	25	44.5 Å²	44.5	15%	0.152	27%	0.266	C	S	.	.	H	α-helix	trans	-65.9	-39.6	-175.4	171.6	0	0	0	0	112.5	K88 L91 V92 L146 V147	K88-V150 HydrophobicContact CB-CG1 4.34Å; K88-V150 HydrophobicContact CD-CG1 4.26Å; K88-V150 WeakPolarHBondContact CD-O 3.39Å; K88-V150 WeakPolarHBondContact CE-O 3.32Å; K88-V150 HydrophobicContact CG-CG1 4.28Å; K88-V150 PolarHBondContact NZ-O 3.27Å; L91-V150 HydrophobicContact CB-CG2 4.24Å; V92-V150 HydrophobicContact CG2-CG2 3.83Å; L146-V150 HydrophobicContact CD1-CG2 3.66Å; L146-V150 HydrophobicContact CG-CG2 4.38Å; L146-V150 WeakPolarHBondContact O-CG2 3.43Å; L146-V150 PolarHBondContact O-N 3.48Å; V147-V150 PolarHBondContact O-N 3.28Å
151	N	82	Confident	87	Confident	98 Å²	98	41.6 Å²	41.6	52%	0.524	25%	0.251	S	S	.	.	H	α-helix	trans	-89.9	-12.4	178.8	-68	-6.7	0	0	0	113.1	V147 F149 S153	V147-N151 WeakPolarHBondContact O-CB 3.36Å; V147-N151 PolarHBondContact O-N 2.92Å; F149-N151 PolarHBondContact O-N 3.28Å; N151-S153 PolarHBondContact O-N 3.3Å; N151-S153 VanDerWaalsContact O-N 3.16Å
152	S	79.3	Confident	86.9	Confident	68 Å²	68	43.9 Å²	43.9	48%	0.476	26%	0.262	S	S	.	.	T	Hydrogen-bonded Turn	trans	52.9	30.5	-173.1	-44.3	0	0	0	0	113	R148 F149	R148-S152 VanDerWaalsContact O-CA 3.22Å; R148-S152 WeakPolarHBondContact O-CA 3.25Å; R148-S152 PolarHBondContact O-N 3.48Å; F149-S152 PolarHBondContact O-N 2.94Å; F149-S152 PolarHBondContact O-OG 3.44Å
153	S	79.3	Confident	86.9	Confident	25 Å²	25	47.5 Å²	47.5	18%	0.175	28%	0.28	C	S	.	.	S	Bend	trans	-160.9	149.1	-175	-172.4	0	0	0	0	109.9	R148 N151 S239	R148-S153 PolarHBondContact O-N 2.96Å; N151-S153 PolarHBondContact O-N 3.3Å; N151-S153 VanDerWaalsContact O-N 3.16Å; S153-S239 CarbonylContact C-O 3.51Å; S153-S239 WeakPolarHBondContact CA-O 3.49Å; S153-S239 PolarHBondContact OG-N 2.88Å; S153-S239 VanDerWaalsContact OG-N 3.15Å
154	W	83.3	Confident	86.8	Confident	8 Å²	8	45.7 Å²	45.7	3%	0.03	27%	0.268	C	S	.	.			trans	-96.4	99.1	-177.6	-174.8	-92.7	0	0	0	112.1	F144 R148 F156 G157 M160 C161 L227 S239 C241	F144-W154 HydrophobicContact CB-CH2 3.84Å; F144-W154 HydrophobicContact CB-CZ3 4.32Å; R148-W154 HydrophobicContact CB-CE3 3.93Å; R148-W154 HydrophobicContact CB-CZ3 4.18Å; R148-W154 HydrophobicContact CG-CE3 3.88Å; R148-W154 HydrophobicContact CG-CZ3 4.45Å; W154-F156 HydrophobicContact CD2-CD2 4.24Å; W154-F156 HydrophobicContact CE3-CD2 4.38Å; W154-F156 HydrophobicContact CH2-CD2 4.15Å; W154-F156 HydrophobicContact CZ2-CB 3.9Å; W154-F156 AromaticContact CZ2-CD2 3.96Å; W154-F156 HydrophobicContact CZ2-CD2 3.96Å; W154-F156 HydrophobicContact CZ2-CG 4.39Å; W154-F156 HydrophobicContact CZ3-CD2 4.34Å; W154-G157 PolarHBondContact NE1-O 3.33Å; W154-M160 VanDerWaalsContact CZ2-C 3.45Å; W154-M160 HydrophobicContact CZ2-CB 3.86Å; W154-M160 WeakPolarHBondContact CZ2-O 3.3Å; W154-C161 HydrophobicContact CZ2-CB 4.21Å; W154-L227 HydrophobicContact CB-CD1 4.02Å; W154-L227 HydrophobicContact CG-CD1 3.96Å; W154-S239 WeakPolarHBondContact CB-O 3.36Å; W154-S239 PolarHBondContact N-O 3.27Å; W154-C241 HydrophobicContact CB-CB 4.3Å; W154-C241 HydrophobicContact CD2-CB 3.8Å; W154-C241 HydrophobicContact CE3-CB 3.97Å; W154-C241 HydrophobicContact CG-CB 3.93Å
155	G	84.1	Confident	86.7	Confident	68 Å²	68	45.1 Å²	45.1	70%	0.701	27%	0.265	S	S	*	.			trans	-83.6	-4.2	-177.3	0	0	0	0	0	116.4
156	F	86.4	Confident	87.1	Confident	72 Å²	72	47.2 Å²	47.2	32%	0.316	27%	0.274	S	S	.	.	S	Bend	trans	-100.2	12.3	-165.1	-52.5	-77.2	0	0	0	115.2	F144 V147 W154 M160	F144-F156 HydrophobicContact CB-CD2 4.3Å; F144-F156 HydrophobicContact CB-CE2 4.12Å; F144-F156 HydrophobicContact CD1-CB 4.28Å; F144-F156 AromaticContact CD1-CD1 3.64Å; F144-F156 HydrophobicContact CD1-CD1 3.64Å; F144-F156 AromaticContact CD1-CD2 3.72Å; F144-F156 HydrophobicContact CD1-CD2 3.72Å; F144-F156 AromaticContact CD1-CE1 3.74Å; F144-F156 HydrophobicContact CD1-CE1 3.74Å; F144-F156 AromaticContact CD1-CE2 3.81Å; F144-F156 HydrophobicContact CD1-CE2 3.81Å; F144-F156 AromaticContact CD1-CG 3.62Å; F144-F156 HydrophobicContact CD1-CG 3.62Å; F144-F156 AromaticContact CD1-CZ 3.8Å; F144-F156 HydrophobicContact CD1-CZ 3.8Å; F144-F156 AromaticContact CE1-CD1 3.79Å; F144-F156 HydrophobicContact CE1-CD1 3.79Å; F144-F156 AromaticContact CE1-CE1 3.96Å; F144-F156 HydrophobicContact CE1-CE1 3.96Å; F144-F156 HydrophobicContact CE1-CG 4.14Å; F144-F156 HydrophobicContact CE1-CZ 4.45Å; F144-F156 HydrophobicContact CG-CE2 4.45Å; V147-F156 HydrophobicContact CB-CE2 3.81Å; V147-F156 HydrophobicContact CB-CZ 3.65Å; V147-F156 HydrophobicContact CG1-CE2 3.78Å; V147-F156 HydrophobicContact CG1-CZ 3.6Å; V147-F156 HydrophobicContact CG2-CZ 4.06Å; W154-F156 HydrophobicContact CD2-CD2 4.24Å; W154-F156 HydrophobicContact CE3-CD2 4.38Å; W154-F156 HydrophobicContact CH2-CD2 4.15Å; W154-F156 HydrophobicContact CZ2-CB 3.9Å; W154-F156 AromaticContact CZ2-CD2 3.96Å; W154-F156 HydrophobicContact CZ2-CD2 3.96Å; W154-F156 HydrophobicContact CZ2-CG 4.39Å; W154-F156 HydrophobicContact CZ3-CD2 4.34Å; F156-M160 HydrophobicContact CB-CB 3.74Å; F156-M160 HydrophobicContact CB-CG 4.19Å
157	G	87.9	Confident	87.4	Confident	37 Å²	37	46.7 Å²	46.7	38%	0.381	27%	0.271	S	S	.	.	H	α-helix	trans	66.8	-179.4	-179.6	0	0	0	0	0	114.7	W154 C161	W154-G157 PolarHBondContact NE1-O 3.33Å; G157-C161 PolarHBondContact O-N 3.14Å
158	K	87.7	Confident	87.6	Confident	139 Å²	139	44.9 Å²	44.9	60%	0.604	26%	0.259	S	S	*	.	H	α-helix	trans	-65.3	-45.5	-172.1	-176.7	174.1	178	179.2	0	112.9	M160 C161 H162 L227	K158-M160 PolarHBondContact O-N 3.22Å; K158-C161 VanDerWaalsContact O-CB 3.32Å; K158-C161 WeakPolarHBondContact O-CB 3.44Å; K158-C161 PolarHBondContact O-N 2.76Å; K158-H162 WeakPolarHBondContact CE-NE2 3.44Å; K158-H162 WeakPolarHBondContact CG-NE2 3.26Å; K158-H162 PolarHBondContact O-CD2 3.37Å; K158-H162 PolarHBondContact O-N 3.06Å; K158-L227 HydrophobicContact CB-CD2 4.28Å
159	G	89.3	Confident	88	Confident	44 Å²	44	42.6 Å²	42.6	45%	0.454	25%	0.251	S	S	.	.	H	α-helix	trans	-55.4	-50.5	-176.7	0	0	0	0	0	113.3	C161 H162 I163	G159-C161 VanDerWaalsContact C-N 3.28Å; G159-C161 PolarHBondContact O-N 3.11Å; G159-H162 PolarHBondContact O-N 3Å; G159-I163 VanDerWaalsContact O-CG1 3.3Å; G159-I163 WeakPolarHBondContact O-CG1 3.33Å; G159-I163 PolarHBondContact O-N 3.32Å
160	M	90.3	Very high	88.6	Confident	41 Å²	41	41.3 Å²	41.3	20%	0.202	25%	0.245	C	C	.	.	H	α-helix	trans	-68.3	-24.5	178.7	-73.4	-54.4	-48.6	0	0	113.7	F144 W154 F156 K158 I163 S164	F144-M160 HydrophobicContact CD1-CE 4.05Å; F144-M160 HydrophobicContact CD2-CE 3.95Å; F144-M160 HydrophobicContact CE1-CE 3.81Å; F144-M160 HydrophobicContact CE1-CG 4.28Å; F144-M160 HydrophobicContact CE1-SD 4.48Å; F144-M160 HydrophobicContact CE2-CE 3.71Å; F144-M160 HydrophobicContact CG-CE 4.12Å; F144-M160 HydrophobicContact CZ-CE 3.65Å; F144-M160 HydrophobicContact CZ-SD 4.44Å; W154-M160 VanDerWaalsContact CZ2-C 3.45Å; W154-M160 HydrophobicContact CZ2-CB 3.86Å; W154-M160 WeakPolarHBondContact CZ2-O 3.3Å; F156-M160 HydrophobicContact CB-CB 3.74Å; F156-M160 HydrophobicContact CB-CG 4.19Å; K158-M160 PolarHBondContact O-N 3.22Å; M160-I163 HydrophobicContact CE-CB 4.21Å; M160-I163 HydrophobicContact CE-CG2 3.99Å; M160-I163 PolarHBondContact O-N 3.41Å; M160-I163 HydrophobicContact SD-CB 4.32Å; M160-I163 HydrophobicContact SD-CD1 4.05Å; M160-I163 HydrophobicContact SD-CG2 4.34Å; M160-S164 VanDerWaalsContact O-CB 3.24Å; M160-S164 WeakPolarHBondContact O-CB 3.38Å; M160-S164 PolarHBondContact O-N 2.92Å
161	C	89.6	Confident	89.1	Confident	0 Å²	0	40.3 Å²	40.3	0%	0	24%	0.239	C	C	.	.	H	α-helix	trans	-63.4	-47.3	175.7	172.8	0	0	0	0	110.6	W154 G157 K158 G159 R165 C241	W154-C161 HydrophobicContact CZ2-CB 4.21Å; G157-C161 PolarHBondContact O-N 3.14Å; K158-C161 VanDerWaalsContact O-CB 3.32Å; K158-C161 WeakPolarHBondContact O-CB 3.44Å; K158-C161 PolarHBondContact O-N 2.76Å; G159-C161 VanDerWaalsContact C-N 3.28Å; G159-C161 PolarHBondContact O-N 3.11Å; C161-R165 PolarHBondContact O-N 3.27Å; C161-C241 WeakPolarHBondContact CA-SG 3.42Å; C161-C241 HydrophobicContact CB-CB 3.91Å; C161-C241 WeakPolarHBondContact CB-SG 3.18Å; C161-C241 VanDerWaalsContact SG-CA 3.58Å; C161-C241 WeakPolarHBondContact SG-CB 3.31Å; C161-C241 CovalentContact SG-SG 2.03Å; C161-C241 PolarHBondContact SG-SG 2.76Å
162	H	91	Very high	89.6	Confident	50 Å²	50	36 Å²	36	23%	0.231	22%	0.216	C	C	.	.	H	α-helix	trans	-65.1	-47.1	172.8	-58.3	-74.3	0	0	0	111.9	K158 G159 R165 F166 A222 Q225	K158-H162 WeakPolarHBondContact CE-NE2 3.44Å; K158-H162 WeakPolarHBondContact CG-NE2 3.26Å; K158-H162 PolarHBondContact O-CD2 3.37Å; K158-H162 PolarHBondContact O-N 3.06Å; G159-H162 PolarHBondContact O-N 3Å; H162-R165 PolarHBondContact O-N 2.93Å; H162-F166 WeakPolarHBondContact O-CB 3.2Å; H162-F166 PolarHBondContact O-N 3.06Å; H162-A222 PolarHBondContact ND1-O 2.85Å; H162-Q225 PolarHBondContact CE1-O 3.48Å; H162-Q225 PolarHBondContact ND1-O 3.48Å; H162-Q225 VanDerWaalsContact ND1-O 3.12Å
163	I	93.3	Very high	90.4	Very high	76 Å²	76	32.8 Å²	32.8	39%	0.39	19%	0.194	S	C	.	.	H	α-helix	trans	-63.6	-45.5	-175.7	-67.1	163.9	0	0	0	112.1	G159 M160 R165 F166 V167	G159-I163 VanDerWaalsContact O-CG1 3.3Å; G159-I163 WeakPolarHBondContact O-CG1 3.33Å; G159-I163 PolarHBondContact O-N 3.32Å; M160-I163 HydrophobicContact CE-CB 4.21Å; M160-I163 HydrophobicContact CE-CG2 3.99Å; M160-I163 PolarHBondContact O-N 3.41Å; M160-I163 HydrophobicContact SD-CB 4.32Å; M160-I163 HydrophobicContact SD-CD1 4.05Å; M160-I163 HydrophobicContact SD-CG2 4.34Å; I163-R165 VanDerWaalsContact C-N 3.32Å; I163-R165 PolarHBondContact O-N 2.9Å; I163-F166 PolarHBondContact O-N 3.08Å; I163-V167 HydrophobicContact CG2-CG2 4.33Å; I163-V167 WeakPolarHBondContact O-CB 3.41Å; I163-V167 WeakPolarHBondContact O-CG2 3.24Å; I163-V167 PolarHBondContact O-N 3.12Å
164	S	91	Very high	91.2	Very high	5 Å²	5	31.6 Å²	31.6	4%	0.035	19%	0.185	C	C	.	.	H	α-helix	trans	-60.1	-43.6	179.1	-169.2	0	0	0	0	110.9	N141 M160 Q168	N141-S164 PolarHBondContact OD1-O 3.47Å; N141-S164 PolarHBondContact OD1-OG 3.33Å; M160-S164 VanDerWaalsContact O-CB 3.24Å; M160-S164 WeakPolarHBondContact O-CB 3.38Å; M160-S164 PolarHBondContact O-N 2.92Å; S164-Q168 WeakPolarHBondContact O-CB 3.35Å; S164-Q168 PolarHBondContact O-N 3.49Å
165	R	89.5	Confident	91.8	Very high	29 Å²	29	31.4 Å²	31.4	11%	0.109	19%	0.185	C	C	.	.	H	α-helix	trans	-69.9	-41.5	179.6	-164.5	68.3	166.5	118.5	13.2	112.2	C161 H162 I163 Q168 Y169 H221 Q225	C161-R165 PolarHBondContact O-N 3.27Å; H162-R165 PolarHBondContact O-N 2.93Å; I163-R165 VanDerWaalsContact C-N 3.32Å; I163-R165 PolarHBondContact O-N 2.9Å; R165-Q168 PolarHBondContact O-N 3.2Å; R165-Y169 PolarHBondContact NH1-OH 3.4Å; R165-Y169 PolarHBondContact NH2-OH 3.04Å; R165-Y169 PolarHBondContact O-N 3.12Å; R165-H221 VanDerWaalsContact CG-O 3.27Å; R165-H221 WeakPolarHBondContact CG-O 3.49Å; R165-Q225 HydrophobicContact CB-CB 4.4Å; R165-Q225 HydrophobicContact CB-CG 4.08Å; R165-Q225 HydrophobicContact CG-CB 4.26Å; R165-Q225 HydrophobicContact CG-CG 4.11Å
166	F	94.5	Very high	92.3	Very high	52 Å²	52	28.2 Å²	28.2	23%	0.228	15%	0.152	C	C	.	.	H	α-helix	trans	-57.6	-52.7	173.2	177.5	-105.1	0	0	0	111.6	H162 I163 Q168 Y169 C170 L219 A222	H162-F166 WeakPolarHBondContact O-CB 3.2Å; H162-F166 PolarHBondContact O-N 3.06Å; I163-F166 PolarHBondContact O-N 3.08Å; F166-Q168 VanDerWaalsContact C-N 3.29Å; F166-Q168 PolarHBondContact O-N 2.88Å; F166-Y169 PolarHBondContact O-N 3.42Å; F166-C170 HydrophobicContact CD1-CB 4.38Å; F166-C170 HydrophobicContact CE1-CB 4.03Å; F166-C170 HydrophobicContact CE2-CB 4.39Å; F166-C170 HydrophobicContact CZ-CB 4.03Å; F166-C170 WeakPolarHBondContact O-CB 3.29Å; F166-C170 PolarHBondContact O-N 2.85Å; F166-L219 HydrophobicContact CE2-CD2 4.32Å; F166-L219 HydrophobicContact CE2-CG 4.17Å; F166-A222 HydrophobicContact CB-CB 3.67Å; F166-A222 HydrophobicContact CD2-CB 4.11Å; F166-A222 HydrophobicContact CG-CB 4.36Å
167	V	95.5	Very high	92.7	Very high	6 Å²	6	26.1 Å²	26.1	4%	0.036	14%	0.144	C	C	.	.	H	α-helix	trans	-62.9	-37.7	-178.3	170.6	0	0	0	0	111.3	L136 I137 L140 I163 Y169 C170 S171	L136-V167 HydrophobicContact CB-CG1 4.48Å; L136-V167 HydrophobicContact CD2-CG1 4.14Å; L136-V167 HydrophobicContact CD2-CG2 4.34Å; L136-V167 HydrophobicContact CG-CG1 3.84Å; L136-V167 HydrophobicContact CG-CG2 4.35Å; I137-V167 HydrophobicContact CB-CG1 4.19Å; I137-V167 HydrophobicContact CG1-CG1 4.49Å; L140-V167 HydrophobicContact CB-CB 4.41Å; L140-V167 HydrophobicContact CB-CG1 4.2Å; L140-V167 HydrophobicContact CB-CG2 4.06Å; L140-V167 HydrophobicContact CD1-CG2 4.06Å; I163-V167 HydrophobicContact CG2-CG2 4.33Å; I163-V167 WeakPolarHBondContact O-CB 3.41Å; I163-V167 WeakPolarHBondContact O-CG2 3.24Å; I163-V167 PolarHBondContact O-N 3.12Å; V167-Y169 PolarHBondContact O-N 3.37Å; V167-C170 PolarHBondContact O-N 2.73Å; V167-S171 WeakPolarHBondContact O-CB 3.45Å; V167-S171 PolarHBondContact O-N 3.39Å
168	Q	92.9	Very high	93.1	Very high	12 Å²	12	24.3 Å²	24.3	6%	0.056	13%	0.126	C	C	.	.	H	α-helix	trans	-55	-52.6	178.1	-169.2	-171	20.9	0	0	112.1	I137 S164 R165 F166 L172 H348 M352	I137-Q168 HydrophobicContact CD1-CG 4.45Å; S164-Q168 WeakPolarHBondContact O-CB 3.35Å; S164-Q168 PolarHBondContact O-N 3.49Å; R165-Q168 PolarHBondContact O-N 3.2Å; F166-Q168 VanDerWaalsContact C-N 3.29Å; F166-Q168 PolarHBondContact O-N 2.88Å; Q168-L172 WeakPolarHBondContact O-CB 3.24Å; Q168-L172 PolarHBondContact O-N 3.35Å; Q168-H348 PolarHBondContact NE2-CE1 3.32Å; Q168-M352 HydrophobicContact CG-CE 4.31Å
169	Y	92.9	Very high	93.4	Very high	12 Å²	12	18 Å²	18	5%	0.047	10%	0.098	C	C	.	.	H	α-helix	trans	-75.2	-38.1	176.3	-76.3	-78.6	0	0	0	112.4	R165 F166 V167 S171 L172 H173 S218 H221 D257 T260	R165-Y169 PolarHBondContact NH1-OH 3.4Å; R165-Y169 PolarHBondContact NH2-OH 3.04Å; R165-Y169 PolarHBondContact O-N 3.12Å; F166-Y169 PolarHBondContact O-N 3.42Å; V167-Y169 PolarHBondContact O-N 3.37Å; Y169-S171 PolarHBondContact O-N 2.65Å; Y169-L172 HydrophobicContact CD1-CD2 4.36Å; Y169-L172 WeakPolarHBondContact O-CB 3.5Å; Y169-L172 PolarHBondContact O-N 3.32Å; Y169-H173 AromaticContact CD1-CE1 3.94Å; Y169-H173 AromaticContact CD1-NE2 3.85Å; Y169-H173 WeakPolarHBondContact O-CB 3.25Å; Y169-H173 PolarHBondContact O-N 3.02Å; Y169-H173 PolarHBondContact O-ND1 3.16Å; Y169-S218 VanDerWaalsContact CB-OG 3.27Å; Y169-S218 WeakPolarHBondContact CB-OG 3.22Å; Y169-S218 PolarHBondContact O-OG 3.22Å; Y169-H221 HydrophobicContact CD2-CB 3.44Å; Y169-H221 VanDerWaalsContact CD2-CB 3.44Å; Y169-H221 AromaticContact CD2-CD2 3.98Å; Y169-H221 AromaticContact CD2-CG 3.59Å; Y169-H221 AromaticContact CE1-CE1 3.94Å; Y169-H221 AromaticContact CE1-NE2 3.92Å; Y169-H221 HydrophobicContact CE2-CB 3.42Å; Y169-H221 VanDerWaalsContact CE2-CB 3.42Å; Y169-H221 AromaticContact CE2-CD2 3.89Å; Y169-H221 AromaticContact CE2-CE1 3.91Å; Y169-H221 AromaticContact CE2-CG 3.27Å; Y169-H221 AromaticContact CE2-ND1 3.31Å; Y169-H221 VanDerWaalsContact CE2-ND1 3.31Å; Y169-H221 WeakPolarHBondContact CE2-ND1 3.37Å; Y169-H221 HydrophobicContact CG-CB 4.31Å; Y169-H221 AromaticContact CZ-CD2 3.99Å; Y169-H221 AromaticContact CZ-CE1 3.49Å; Y169-H221 VanDerWaalsContact CZ-CE1 3.49Å; Y169-H221 AromaticContact CZ-CG 3.66Å; Y169-H221 AromaticContact CZ-ND1 3.36Å; Y169-H221 AromaticContact CZ-NE2 3.88Å; Y169-H221 PolarHBondContact OH-CE1 2.89Å; Y169-H221 PolarHBondContact OH-ND1 2.89Å; Y169-D257 PolarHBondContact OH-OD1 3.38Å; Y169-T260 HydrophobicContact CD1-CG2 4.29Å; Y169-T260 HydrophobicContact CE1-CG2 4.2Å
170	C	95.9	Very high	93.7	Very high	1 Å²	1	16.5 Å²	16.5	1%	0.007	8%	0.081	C	C	.	.	H	α-helix	trans	-63.2	-47	-176.5	-168.5	0	0	0	0	111.5	F166 V167 L172 H173 V174 S218	F166-C170 HydrophobicContact CD1-CB 4.38Å; F166-C170 HydrophobicContact CE1-CB 4.03Å; F166-C170 HydrophobicContact CE2-CB 4.39Å; F166-C170 HydrophobicContact CZ-CB 4.03Å; F166-C170 WeakPolarHBondContact O-CB 3.29Å; F166-C170 PolarHBondContact O-N 2.85Å; V167-C170 PolarHBondContact O-N 2.73Å; C170-L172 VanDerWaalsContact C-N 3.34Å; C170-L172 PolarHBondContact O-N 3.24Å; C170-H173 PolarHBondContact O-N 3.1Å; C170-V174 WeakPolarHBondContact O-CB 3.45Å; C170-V174 VanDerWaalsContact O-CG2 3.26Å; C170-V174 WeakPolarHBondContact O-CG2 3.44Å; C170-V174 PolarHBondContact O-N 3.47Å; C170-S218 VanDerWaalsContact CA-OG 3.24Å; C170-S218 WeakPolarHBondContact CA-OG 3.35Å; C170-S218 PolarHBondContact N-OG 3.33Å
171	S	95.7	Very high	93.8	Very high	3 Å²	3	15.2 Å²	15.2	2%	0.021	8%	0.077	C	C	.	.	H	α-helix	trans	-65.1	-35.1	174.5	-74.8	0	0	0	0	112.9	A133 V167 Y169 S175	A133-S171 WeakPolarHBondContact O-CB 3.37Å; A133-S171 PolarHBondContact O-OG 2.84Å; V167-S171 WeakPolarHBondContact O-CB 3.45Å; V167-S171 PolarHBondContact O-N 3.39Å; Y169-S171 PolarHBondContact O-N 2.65Å; S171-S175 VanDerWaalsContact O-CB 3.26Å; S171-S175 WeakPolarHBondContact O-CB 3.43Å; S171-S175 PolarHBondContact O-N 3.41Å; S171-S175 PolarHBondContact O-OG 2.76Å; S171-S175 VanDerWaalsContact O-OG 3.04Å
172	L	93.3	Very high	94	Very high	7 Å²	7	15.3 Å²	15.3	4%	0.037	8%	0.077	C	C	.	.	H	α-helix	trans	-58.6	-55.9	171.2	167.3	64.3	0	0	0	110.7	Q168 Y169 C170 S175 T176 F318 W322	Q168-L172 WeakPolarHBondContact O-CB 3.24Å; Q168-L172 PolarHBondContact O-N 3.35Å; Y169-L172 HydrophobicContact CD1-CD2 4.36Å; Y169-L172 WeakPolarHBondContact O-CB 3.5Å; Y169-L172 PolarHBondContact O-N 3.32Å; C170-L172 VanDerWaalsContact C-N 3.34Å; C170-L172 PolarHBondContact O-N 3.24Å; L172-S175 PolarHBondContact O-N 2.86Å; L172-T176 PolarHBondContact O-N 2.91Å; L172-T176 PolarHBondContact O-OG1 3.4Å; L172-T176 VanDerWaalsContact O-OG1 3.09Å; L172-F318 HydrophobicContact CD1-CE1 4.5Å; L172-F318 HydrophobicContact CD1-CE2 4.45Å; L172-F318 HydrophobicContact CD1-CZ 3.77Å; L172-W322 HydrophobicContact CB-CH2 4.15Å; L172-W322 HydrophobicContact CB-CZ3 4.19Å; L172-W322 HydrophobicContact CD1-CD2 3.67Å; L172-W322 HydrophobicContact CD1-CE3 3.67Å; L172-W322 HydrophobicContact CD1-CG 4.07Å; L172-W322 HydrophobicContact CD1-CH2 4.44Å; L172-W322 HydrophobicContact CD1-CZ2 4.47Å; L172-W322 HydrophobicContact CD1-CZ3 4.06Å; L172-W322 HydrophobicContact CD2-CE3 4.11Å; L172-W322 HydrophobicContact CD2-CZ3 4.06Å; L172-W322 HydrophobicContact CG-CE3 4.36Å; L172-W322 HydrophobicContact CG-CZ3 4.33Å
173	H	94.6	Very high	94	Very high	2 Å²	2	13 Å²	13	1%	0.009	7%	0.066	C	C	.	.	H	α-helix	trans	-63.8	-44.6	-177.2	-61.3	158.2	0	0	0	112.2	Y169 C170 S175 T176 L177 A214 S218 T260	Y169-H173 AromaticContact CD1-CE1 3.94Å; Y169-H173 AromaticContact CD1-NE2 3.85Å; Y169-H173 WeakPolarHBondContact O-CB 3.25Å; Y169-H173 PolarHBondContact O-N 3.02Å; Y169-H173 PolarHBondContact O-ND1 3.16Å; C170-H173 PolarHBondContact O-N 3.1Å; H173-S175 VanDerWaalsContact C-N 3.27Å; H173-S175 PolarHBondContact O-N 3.41Å; H173-T176 PolarHBondContact O-N 3.32Å; H173-L177 VanDerWaalsContact O-CB 3.3Å; H173-L177 WeakPolarHBondContact O-CB 3.42Å; H173-L177 WeakPolarHBondContact O-CG 3.28Å; H173-L177 PolarHBondContact O-N 3.12Å; H173-A214 HydrophobicContact CB-CB 3.63Å; H173-S218 PolarHBondContact ND1-OG 3.33Å; H173-T260 WeakPolarHBondContact NE2-CG2 3.34Å
174	V	96.8	Very high	93.9	Very high	0 Å²	0	12.4 Å²	12.4	0%	0	6%	0.064	C	C	.	.	H	α-helix	trans	-56.5	-44.3	173.7	169.9	0	0	0	0	110.2	N129 A133 C170 T178 I210 W211 A214	N129-V174 WeakPolarHBondContact ND2-CG1 3.49Å; A133-V174 HydrophobicContact CB-CB 4.25Å; A133-V174 HydrophobicContact CB-CG1 3.84Å; C170-V174 WeakPolarHBondContact O-CB 3.45Å; C170-V174 VanDerWaalsContact O-CG2 3.26Å; C170-V174 WeakPolarHBondContact O-CG2 3.44Å; C170-V174 PolarHBondContact O-N 3.47Å; V174-T178 WeakPolarHBondContact O-CB 3.49Å; V174-T178 PolarHBondContact O-N 2.71Å; V174-T178 PolarHBondContact O-OG1 3.38Å; V174-I210 HydrophobicContact CB-CG2 4.3Å; V174-I210 HydrophobicContact CG1-CG2 4.07Å; V174-I210 HydrophobicContact CG2-CG2 4.31Å; V174-W211 HydrophobicContact CG1-CZ2 4.01Å; V174-W211 HydrophobicContact CG2-CD2 3.78Å; V174-W211 HydrophobicContact CG2-CE3 3.73Å; V174-W211 HydrophobicContact CG2-CG 4.33Å; V174-W211 HydrophobicContact CG2-CH2 4.22Å; V174-W211 HydrophobicContact CG2-CZ2 4.26Å; V174-W211 HydrophobicContact CG2-CZ3 3.96Å; V174-A214 HydrophobicContact CB-CB 4.44Å; V174-A214 HydrophobicContact CG2-CB 3.49Å; V174-A214 VanDerWaalsContact CG2-CB 3.49Å
175	S	95.4	Very high	93.8	Very high	4 Å²	4	12.5 Å²	12.5	3%	0.028	6%	0.064	C	C	.	.	H	α-helix	trans	-65.4	-49.9	179	-72.3	0	0	0	0	112.7	S171 L172 H173 L177 T178 L179	S171-S175 VanDerWaalsContact O-CB 3.26Å; S171-S175 WeakPolarHBondContact O-CB 3.43Å; S171-S175 PolarHBondContact O-N 3.41Å; S171-S175 PolarHBondContact O-OG 2.76Å; S171-S175 VanDerWaalsContact O-OG 3.04Å; L172-S175 PolarHBondContact O-N 2.86Å; H173-S175 VanDerWaalsContact C-N 3.27Å; H173-S175 PolarHBondContact O-N 3.41Å; S175-L177 PolarHBondContact O-N 3.16Å; S175-T178 PolarHBondContact O-N 2.79Å; S175-L179 WeakPolarHBondContact O-CG 3.46Å; S175-L179 PolarHBondContact O-N 3.42Å
176	T	94.7	Very high	93.7	Very high	0 Å²	0	13.5 Å²	13.5	0%	0	7%	0.068	C	C	.	.	H	α-helix	trans	-60.6	-45.8	179	-39	0	0	0	0	112	L172 H173 T178 L179 T180 L264 P268 F318	L172-T176 PolarHBondContact O-N 2.91Å; L172-T176 PolarHBondContact O-OG1 3.4Å; L172-T176 VanDerWaalsContact O-OG1 3.09Å; H173-T176 PolarHBondContact O-N 3.32Å; T176-T178 VanDerWaalsContact C-N 3.34Å; T176-T178 PolarHBondContact O-N 3.06Å; T176-L179 PolarHBondContact O-N 3.04Å; T176-T180 PolarHBondContact O-N 2.82Å; T176-T180 PolarHBondContact O-OG1 2.95Å; T176-L264 WeakPolarHBondContact CB-O 3.43Å; T176-L264 WeakPolarHBondContact CG2-O 3.49Å; T176-L264 PolarHBondContact OG1-O 2.78Å; T176-P268 HydrophobicContact CG2-CB 3.42Å; T176-P268 VanDerWaalsContact CG2-CB 3.42Å; T176-P268 HydrophobicContact CG2-CG 3.98Å; T176-F318 HydrophobicContact CG2-CE1 4.04Å; T176-F318 WeakPolarHBondContact OG1-CE1 3.5Å; T176-F318 VanDerWaalsContact OG1-CZ 3.28Å; T176-F318 WeakPolarHBondContact OG1-CZ 3.38Å
177	L	95.3	Very high	93.4	Very high	28 Å²	28	16.2 Å²	16.2	15%	0.147	8%	0.076	C	C	.	.	H	α-helix	trans	-66.4	-36.5	179.8	-66.4	171.1	0	0	0	111.5	H173 S175 T180 A181 I210 M213 A214 L264	H173-L177 VanDerWaalsContact O-CB 3.3Å; H173-L177 WeakPolarHBondContact O-CB 3.42Å; H173-L177 WeakPolarHBondContact O-CG 3.28Å; H173-L177 PolarHBondContact O-N 3.12Å; S175-L177 PolarHBondContact O-N 3.16Å; L177-T180 WeakPolarHBondContact O-CB 3.4Å; L177-T180 PolarHBondContact O-N 3.31Å; L177-A181 PolarHBondContact O-N 2.88Å; L177-I210 HydrophobicContact CB-CG1 4.1Å; L177-I210 HydrophobicContact CB-CG2 3.92Å; L177-I210 HydrophobicContact CD1-CG2 4.47Å; L177-M213 HydrophobicContact CD1-CB 4.22Å; L177-M213 HydrophobicContact CD1-CE 4.47Å; L177-A214 HydrophobicContact CD1-CB 4.44Å; L177-L264 HydrophobicContact CD2-CD2 4.46Å
178	T	95.7	Very high	93	Very high	0 Å²	0	18.9 Å²	18.9	0%	0	9%	0.088	C	C	.	.	H	α-helix	trans	-67.1	-41.3	174.7	-58.1	0	0	0	0	112	F126 N129 L130 V174 S175 T176 T180 A181 I182	F126-T178 HydrophobicContact CB-CG2 3.62Å; F126-T178 HydrophobicContact CD1-CG2 4.18Å; F126-T178 HydrophobicContact CG-CG2 4.19Å; F126-T178 VanDerWaalsContact O-CG2 3.31Å; F126-T178 WeakPolarHBondContact O-CG2 3.48Å; N129-T178 HydrophobicContact CB-CG2 4.29Å; N129-T178 PolarHBondContact ND2-OG1 2.97Å; L130-T178 HydrophobicContact CD1-CG2 4.23Å; L130-T178 HydrophobicContact CD2-CG2 4.35Å; L130-T178 HydrophobicContact CG-CG2 3.82Å; V174-T178 WeakPolarHBondContact O-CB 3.49Å; V174-T178 PolarHBondContact O-N 2.71Å; V174-T178 PolarHBondContact O-OG1 3.38Å; S175-T178 PolarHBondContact O-N 2.79Å; T176-T178 VanDerWaalsContact C-N 3.34Å; T176-T178 PolarHBondContact O-N 3.06Å; T178-T180 VanDerWaalsContact C-N 3.28Å; T178-T180 PolarHBondContact O-N 3.37Å; T178-A181 PolarHBondContact O-N 3.46Å; T178-I182 HydrophobicContact CG2-CD1 4.14Å; T178-I182 VanDerWaalsContact O-CG1 3.29Å; T178-I182 WeakPolarHBondContact O-CG1 3.47Å; T178-I182 PolarHBondContact O-N 3.35Å
179	L	94.1	Very high	92.7	Very high	5 Å²	5	19.6 Å²	19.6	3%	0.026	9%	0.094	C	C	.	.	H	α-helix	trans	-62.3	-36.8	173.6	-68.5	173.5	0	0	0	111.9	L130 S175 T176 I182 A183 I272 V314 V315 F318	L130-L179 HydrophobicContact CD1-CD2 3.89Å; L130-L179 HydrophobicContact CD2-CD2 4.34Å; L130-L179 HydrophobicContact CD2-CG 4.21Å; S175-L179 WeakPolarHBondContact O-CG 3.46Å; S175-L179 PolarHBondContact O-N 3.42Å; T176-L179 PolarHBondContact O-N 3.04Å; L179-I182 PolarHBondContact O-N 2.93Å; L179-A183 WeakPolarHBondContact O-CB 3.35Å; L179-A183 PolarHBondContact O-N 2.93Å; L179-I272 HydrophobicContact CB-CD1 4.06Å; L179-V314 HydrophobicContact CD1-CG1 4.49Å; L179-V314 HydrophobicContact CD2-CG1 3.49Å; L179-V314 VanDerWaalsContact CD2-CG1 3.49Å; L179-V315 HydrophobicContact CB-CG2 4.26Å; L179-V315 HydrophobicContact CD1-CG2 4.35Å; L179-V315 HydrophobicContact CD2-CG2 4.23Å; L179-F318 HydrophobicContact CD1-CB 3.98Å; L179-F318 HydrophobicContact CD1-CD1 3.91Å; L179-F318 HydrophobicContact CD1-CD2 4.14Å; L179-F318 HydrophobicContact CD1-CE1 4.39Å; L179-F318 HydrophobicContact CD1-CG 3.75Å
180	T	94.8	Very high	92.3	Very high	14 Å²	14	19.5 Å²	19.5	9%	0.086	9%	0.094	C	C	.	.	H	α-helix	trans	-65.2	-46	174	-53.2	0	0	0	0	111.6	T176 L177 T178 I182 A183 L184 P268 I271 I272	T176-T180 PolarHBondContact O-N 2.82Å; T176-T180 PolarHBondContact O-OG1 2.95Å; L177-T180 WeakPolarHBondContact O-CB 3.4Å; L177-T180 PolarHBondContact O-N 3.31Å; T178-T180 VanDerWaalsContact C-N 3.28Å; T178-T180 PolarHBondContact O-N 3.37Å; T180-I182 VanDerWaalsContact C-N 3.35Å; T180-I182 PolarHBondContact O-N 3.38Å; T180-A183 PolarHBondContact O-N 3.5Å; T180-L184 HydrophobicContact CG2-CD1 4.16Å; T180-L184 WeakPolarHBondContact O-CG 3.49Å; T180-L184 PolarHBondContact O-N 3.4Å; T180-P268 WeakPolarHBondContact OG1-CB 3.34Å; T180-I271 HydrophobicContact CG2-CB 4.28Å; T180-I271 HydrophobicContact CG2-CG2 3.72Å; T180-I272 HydrophobicContact CG2-CG1 4.43Å; T180-I272 WeakPolarHBondContact OG1-CD1 3.35Å
181	A	93.8	Very high	91.8	Very high	14 Å²	14	21 Å²	21	12%	0.116	10%	0.101	C	C	.	.	H	α-helix	trans	-60.2	-42	175.4	0	0	0	0	0	112.4	F126 L177 T178 L184 D185 I210	F126-A181 HydrophobicContact CD2-CB 4.46Å; F126-A181 HydrophobicContact CE1-CB 4.14Å; F126-A181 HydrophobicContact CE2-CB 4.06Å; F126-A181 HydrophobicContact CZ-CB 3.89Å; L177-A181 PolarHBondContact O-N 2.88Å; T178-A181 PolarHBondContact O-N 3.46Å; A181-L184 PolarHBondContact O-N 3.48Å; A181-D185 WeakPolarHBondContact O-CB 3.16Å; A181-D185 PolarHBondContact O-N 3.04Å; A181-I210 HydrophobicContact CB-CD1 4.11Å
182	I	92.4	Very high	91.2	Very high	2 Å²	2	25.2 Å²	25.2	1%	0.01	12%	0.12	C	C	.	.	H	α-helix	trans	-62	-44.2	174.2	-67.2	163.3	0	0	0	111.2	T123 F126 L130 T178 L179 T180 L184 R186 L311	T123-I182 HydrophobicContact CG2-CB 4.42Å; T123-I182 HydrophobicContact CG2-CG1 4.04Å; T123-I182 HydrophobicContact CG2-CG2 3.82Å; F126-I182 HydrophobicContact CB-CD1 3.75Å; F126-I182 HydrophobicContact CB-CG1 3.51Å; F126-I182 HydrophobicContact CD2-CG1 3.84Å; F126-I182 HydrophobicContact CG-CG1 4.01Å; L130-I182 HydrophobicContact CD1-CD1 3.81Å; T178-I182 HydrophobicContact CG2-CD1 4.14Å; T178-I182 VanDerWaalsContact O-CG1 3.29Å; T178-I182 WeakPolarHBondContact O-CG1 3.47Å; T178-I182 PolarHBondContact O-N 3.35Å; L179-I182 PolarHBondContact O-N 2.93Å; T180-I182 VanDerWaalsContact C-N 3.35Å; T180-I182 PolarHBondContact O-N 3.38Å; I182-L184 VanDerWaalsContact C-N 3.34Å; I182-L184 PolarHBondContact O-N 3.41Å; I182-R186 HydrophobicContact CG2-CG 4.33Å; I182-R186 VanDerWaalsContact O-CB 3.3Å; I182-R186 WeakPolarHBondContact O-CB 3.46Å; I182-R186 WeakPolarHBondContact O-CG 3.46Å; I182-R186 PolarHBondContact O-N 3.04Å; I182-L311 HydrophobicContact CG2-CD1 3.92Å; I182-L311 HydrophobicContact CG2-CD2 3.68Å; I182-L311 HydrophobicContact CG2-CG 4.41Å
183	A	91.6	Very high	90.5	Very high	0 Å²	0	28.3 Å²	28.3	0%	0	14%	0.141	C	C	.	.	H	α-helix	trans	-63.3	-39.6	178.6	0	0	0	0	0	112.1	L179 T180 R187 I272 A275 Y276	L179-A183 WeakPolarHBondContact O-CB 3.35Å; L179-A183 PolarHBondContact O-N 2.93Å; T180-A183 PolarHBondContact O-N 3.5Å; A183-R187 WeakPolarHBondContact O-CB 3.47Å; A183-R187 PolarHBondContact O-N 3.47Å; A183-I272 HydrophobicContact CB-CB 4.3Å; A183-I272 HydrophobicContact CB-CG1 4Å; A183-I272 HydrophobicContact CB-CG2 4.01Å; A183-A275 HydrophobicContact CB-CB 4.39Å; A183-Y276 WeakPolarHBondContact CA-OH 3.3Å; A183-Y276 HydrophobicContact CB-CE1 4.23Å; A183-Y276 HydrophobicContact CB-CE2 3.86Å
184	L	91.3	Very high	89.8	Confident	65 Å²	65	36.5 Å²	36.5	34%	0.34	18%	0.184	S	C	.	.	H	α-helix	trans	-70.9	-43.5	177.9	-68.4	173.6	0	0	0	112.8	T180 A181 I182 R186 R187 Q188 I271	T180-L184 HydrophobicContact CG2-CD1 4.16Å; T180-L184 WeakPolarHBondContact O-CG 3.49Å; T180-L184 PolarHBondContact O-N 3.4Å; A181-L184 PolarHBondContact O-N 3.48Å; I182-L184 VanDerWaalsContact C-N 3.34Å; I182-L184 PolarHBondContact O-N 3.41Å; L184-R186 VanDerWaalsContact C-N 3.35Å; L184-R186 PolarHBondContact O-N 3.02Å; L184-R187 WeakPolarHBondContact O-CB 3.39Å; L184-R187 PolarHBondContact O-N 3.35Å; L184-Q188 PolarHBondContact O-N 2.84Å; L184-I271 HydrophobicContact CD1-CG2 4.48Å; L184-I271 HydrophobicContact CD2-CG2 4.18Å; L184-I271 HydrophobicContact CG-CG2 4.48Å
185	D	89	Confident	88.9	Confident	6 Å²	6	44.6 Å²	44.6	3%	0.032	22%	0.215	C	C	.	.	H	α-helix	trans	-56.6	-48	170.7	168.5	58.3	0	0	0	110.9	T123 A181 R187 Q188 V189 M198	T123-D185 PolarHBondContact OG1-OD2 3.43Å; A181-D185 WeakPolarHBondContact O-CB 3.16Å; A181-D185 PolarHBondContact O-N 3.04Å; D185-R187 PolarHBondContact O-N 3.41Å; D185-Q188 PolarHBondContact O-N 3.38Å; D185-V189 WeakPolarHBondContact O-CB 3.32Å; D185-V189 WeakPolarHBondContact O-CG2 3.41Å; D185-V189 PolarHBondContact O-N 2.83Å; D185-M198 HydrophobicContact CB-CE 4.4Å
186	R	87.4	Confident	87.9	Confident	51 Å²	51	49.7 Å²	49.7	19%	0.192	25%	0.248	C	C	.	.	H	α-helix	trans	-64.8	-37.4	178.6	-71.8	-80.6	169.2	-79.2	2.6	112.7	T123 I182 L184 I190 Y276 L311	T123-R186 VanDerWaalsContact CB-NH2 3.31Å; T123-R186 VanDerWaalsContact OG1-CZ 3.23Å; T123-R186 PolarHBondContact OG1-NH1 3.15Å; T123-R186 PolarHBondContact OG1-NH2 3.45Å; I182-R186 HydrophobicContact CG2-CG 4.33Å; I182-R186 VanDerWaalsContact O-CB 3.3Å; I182-R186 WeakPolarHBondContact O-CB 3.46Å; I182-R186 WeakPolarHBondContact O-CG 3.46Å; I182-R186 PolarHBondContact O-N 3.04Å; L184-R186 VanDerWaalsContact C-N 3.35Å; L184-R186 PolarHBondContact O-N 3.02Å; R186-I190 WeakPolarHBondContact O-CB 3.44Å; R186-I190 WeakPolarHBondContact O-CD1 3.26Å; R186-I190 VanDerWaalsContact O-CG1 3.25Å; R186-I190 WeakPolarHBondContact O-CG1 3.26Å; R186-I190 PolarHBondContact O-N 3.05Å; R186-Y276 HydrophobicContact CB-CE1 4.36Å; R186-L311 HydrophobicContact CG-CD1 3.63Å
187	R	88.4	Confident	87.3	Confident	108 Å²	108	58.6 Å²	58.6	41%	0.408	28%	0.281	S	S	.	.	H	α-helix	trans	-60	-51.6	170.8	-174.3	-177.8	71.9	118.1	-3.4	110.9	A183 L184 D185 V189 I190 L191 A275 V279	A183-R187 WeakPolarHBondContact O-CB 3.47Å; A183-R187 PolarHBondContact O-N 3.47Å; L184-R187 WeakPolarHBondContact O-CB 3.39Å; L184-R187 PolarHBondContact O-N 3.35Å; D185-R187 PolarHBondContact O-N 3.41Å; R187-V189 PolarHBondContact O-N 3.19Å; R187-I190 PolarHBondContact O-N 3.15Å; R187-L191 HydrophobicContact CG-CD1 3.64Å; R187-L191 HydrophobicContact CG-CG 4.27Å; R187-L191 WeakPolarHBondContact O-CB 3.33Å; R187-L191 VanDerWaalsContact O-CG 3.3Å; R187-L191 WeakPolarHBondContact O-CG 3.33Å; R187-L191 PolarHBondContact O-N 2.9Å; R187-A275 HydrophobicContact CB-CB 4.36Å; R187-V279 HydrophobicContact CB-CG2 4.17Å; R187-V279 HydrophobicContact CG-CG2 4.24Å
188	Q	87.9	Confident	86.6	Confident	62 Å²	62	58.9 Å²	58.9	29%	0.29	28%	0.282	S	S	.	.	H	α-helix	trans	-58.1	-51.9	179.8	179.2	175.2	-30	0	0	111.9	L184 D185 I190 L191 H192	L184-Q188 PolarHBondContact O-N 2.84Å; D185-Q188 PolarHBondContact O-N 3.38Å; Q188-I190 VanDerWaalsContact C-N 3.28Å; Q188-I190 PolarHBondContact O-N 3.24Å; Q188-L191 PolarHBondContact O-N 3.33Å; Q188-H192 PolarHBondContact O-N 3.37Å
189	V	86.1	Confident	86.1	Confident	28 Å²	28	61.1 Å²	61.1	17%	0.17	30%	0.298	C	S	.	.	H	α-helix	trans	-65.7	-26.5	-175.6	173.4	0	0	0	0	113.2	D185 R187 R197	D185-V189 WeakPolarHBondContact O-CB 3.32Å; D185-V189 WeakPolarHBondContact O-CG2 3.41Å; D185-V189 PolarHBondContact O-N 2.83Å; R187-V189 PolarHBondContact O-N 3.19Å; V189-R197 HydrophobicContact CG2-CG 4.29Å
190	I	84.1	Confident	85.7	Confident	10 Å²	10	64.7 Å²	64.7	5%	0.051	32%	0.321	C	S	.	.	H	α-helix	trans	-92.6	-35	-179.3	-62.8	169.4	0	0	0	112.4	R186 R187 Q188 V279 L283 L308	R186-I190 WeakPolarHBondContact O-CB 3.44Å; R186-I190 WeakPolarHBondContact O-CD1 3.26Å; R186-I190 VanDerWaalsContact O-CG1 3.25Å; R186-I190 WeakPolarHBondContact O-CG1 3.26Å; R186-I190 PolarHBondContact O-N 3.05Å; R187-I190 PolarHBondContact O-N 3.15Å; Q188-I190 VanDerWaalsContact C-N 3.28Å; Q188-I190 PolarHBondContact O-N 3.24Å; I190-V279 HydrophobicContact CB-CG1 4.38Å; I190-V279 HydrophobicContact CD1-CG1 3.83Å; I190-V279 HydrophobicContact CG2-CG1 3.98Å; I190-L283 HydrophobicContact CG2-CD2 4.41Å; I190-L308 HydrophobicContact CD1-CD1 4.06Å; I190-L308 HydrophobicContact CD1-CD2 3.93Å; I190-L308 HydrophobicContact CD1-CG 4.21Å
191	L	84.6	Confident	85.4	Confident	31 Å²	31	68.9 Å²	68.9	16%	0.162	35%	0.347	C	S	.	.	H	α-helix	trans	-78	-41.8	177.5	-63	-176.1	0	0	0	112.4	R187 Q188 P193 T278 R282	R187-L191 HydrophobicContact CG-CD1 3.64Å; R187-L191 HydrophobicContact CG-CG 4.27Å; R187-L191 WeakPolarHBondContact O-CB 3.33Å; R187-L191 VanDerWaalsContact O-CG 3.3Å; R187-L191 WeakPolarHBondContact O-CG 3.33Å; R187-L191 PolarHBondContact O-N 2.9Å; Q188-L191 PolarHBondContact O-N 3.33Å; L191-P193 VanDerWaalsContact C-CD 3.49Å; L191-P193 VanDerWaalsContact O-CD 3.27Å; L191-P193 WeakPolarHBondContact O-CD 3.41Å; L191-T278 HydrophobicContact CD1-CG2 4.06Å; L191-R282 HydrophobicContact CD2-CB 3.71Å; L191-R282 HydrophobicContact CD2-CG 3.73Å
192	H	83.6	Confident	85.3	Confident	92 Å²	92	75.6 Å²	75.6	43%	0.426	37%	0.37	S	S	.	.			trans	-120.8	69.8	-173.7	-54.3	-77.4	0	0	0	111.8	Q188 L194 R195	Q188-H192 PolarHBondContact O-N 3.37Å; H192-L194 PolarHBondContact O-N 2.88Å; H192-L194 VanDerWaalsContact O-N 3.1Å; H192-R195 HydrophobicContact CB-CB 4.14Å; H192-R195 HydrophobicContact CB-CG 4.09Å; H192-R195 PolarHBondContact O-N 3.32Å
193	P	79.4	Confident	85.3	Confident	73 Å²	73	75.5 Å²	75.5	47%	0.474	37%	0.369	S	S	.	.	T	Hydrogen-bonded Turn	trans	-65.7	-15.1	-174.2	28.6	-37.1	0	0	0	114.7	L191	L191-P193 VanDerWaalsContact C-CD 3.49Å; L191-P193 VanDerWaalsContact O-CD 3.27Å; L191-P193 WeakPolarHBondContact O-CD 3.41Å
194	L	78.6	Confident	85.3	Confident	174 Å²	174	78.9 Å²	78.9	91%	0.911	39%	0.39	S	S	*	.	T	Hydrogen-bonded Turn	trans	-91.2	-12.7	176.2	-60.3	177.4	0	0	0	113.5	H192	H192-L194 PolarHBondContact O-N 2.88Å; H192-L194 VanDerWaalsContact O-N 3.1Å
195	R	79.6	Confident	85.5	Confident	169 Å²	169	79.7 Å²	79.7	64%	0.638	40%	0.397	S	S	*	.	S	Bend	trans	-77.6	144.3	173.2	-78.3	-171.8	173.2	-169.3	-2.3	109.5	H192 R197	H192-R195 HydrophobicContact CB-CB 4.14Å; H192-R195 HydrophobicContact CB-CG 4.09Å; H192-R195 PolarHBondContact O-N 3.32Å; R195-R197 PolarHBondContact O-N 2.74Å
196	P	74	Confident	85.8	Confident	112 Å²	112	81 Å²	81	73%	0.727	41%	0.407	S	S	*	.	P	Polyproline II helix	trans	-56.8	141.6	176.7	23.2	-33.3	0	0	0	110.9
197	R	80.9	Confident	86.2	Confident	186 Å²	186	79.8 Å²	79.8	70%	0.702	41%	0.405	S	S	*	.	P	Polyproline II helix	trans	-67.5	158.2	174.9	-68	-169.7	170.3	98.6	7.3	110.3	V189 R195 S199	V189-R197 HydrophobicContact CG2-CG 4.29Å; R195-R197 PolarHBondContact O-N 2.74Å; R197-S199 PolarHBondContact O-N 2.93Å
198	M	81.1	Confident	86.6	Confident	34 Å²	34	79.3 Å²	79.3	17%	0.167	41%	0.409	C	S	.	.	P	Polyproline II helix	trans	-58.4	121	170.3	-171	-177.4	-62.8	0	0	109.4	A122 F126 D185 R202	A122-M198 HydrophobicContact CB-CB 3.86Å; A122-M198 HydrophobicContact CB-CG 3.86Å; A122-M198 HydrophobicContact CB-SD 3.83Å; F126-M198 HydrophobicContact CE2-SD 4.1Å; F126-M198 HydrophobicContact CZ-SD 4Å; D185-M198 HydrophobicContact CB-CE 4.4Å; M198-R202 HydrophobicContact CG-CB 3.76Å
199	S	86.4	Confident	87	Confident	48 Å²	48	81 Å²	81	34%	0.336	42%	0.42	S	S	.	.	P	Polyproline II helix	trans	-69	153.5	175.3	59	0	0	0	0	110.6	R197 T201 R202 G203	R197-S199 PolarHBondContact O-N 2.93Å; S199-T201 PolarHBondContact O-N 2.96Å; S199-R202 PolarHBondContact O-N 3.48Å; S199-R202 WeakPolarHBondContact OG-CG 3.45Å; S199-R202 PolarHBondContact OG-N 2.98Å; S199-G203 PolarHBondContact O-N 2.97Å
200	P	85.4	Confident	87.5	Confident	79 Å²	79	79.9 Å²	79.9	51%	0.513	41%	0.413	S	S	.	.	H	α-helix	trans	-53	-40.5	176.2	-27.6	36.2	0	0	0	112.7	L125 R202 G203 V204	L125-P200 HydrophobicContact CD1-CB 4.43Å; L125-P200 WeakPolarHBondContact CD1-O 3.42Å; P200-R202 PolarHBondContact O-N 3.32Å; P200-G203 CarbonylContact O-C 3.58Å; P200-G203 WeakPolarHBondContact O-CA 3.3Å; P200-G203 PolarHBondContact O-N 3.39Å; P200-V204 PolarHBondContact O-N 3.09Å
201	T	88.9	Confident	88.2	Confident	103 Å²	103	82.5 Å²	82.5	63%	0.632	42%	0.422	S	S	*	.	H	α-helix	trans	-57	-44.9	176	-33.2	0	0	0	0	112.5	S199 G203 V204 V205	S199-T201 PolarHBondContact O-N 2.96Å; T201-G203 VanDerWaalsContact C-N 3.3Å; T201-G203 PolarHBondContact O-N 3.01Å; T201-V204 PolarHBondContact O-N 2.95Å; T201-V205 WeakPolarHBondContact O-CG2 3.24Å; T201-V205 PolarHBondContact O-N 2.99Å
202	R	90.5	Very high	88.8	Confident	155 Å²	155	84.9 Å²	84.9	59%	0.585	44%	0.438	S	S	*	.	H	α-helix	trans	-67.8	-31	175	-72.7	-177	65.6	-176.4	1.7	112.4	M198 S199 P200 C206	M198-R202 HydrophobicContact CG-CB 3.76Å; S199-R202 PolarHBondContact O-N 3.48Å; S199-R202 WeakPolarHBondContact OG-CG 3.45Å; S199-R202 PolarHBondContact OG-N 2.98Å; P200-R202 PolarHBondContact O-N 3.32Å; R202-C206 VanDerWaalsContact O-CB 3.27Å; R202-C206 WeakPolarHBondContact O-CB 3.27Å; R202-C206 PolarHBondContact O-N 2.92Å
203	G	91.8	Very high	89.3	Confident	0 Å²	0	84.4 Å²	84.4	0%	0	44%	0.437	C	S	.	.	H	α-helix	trans	-63.1	-46	170.2	0	0	0	0	0	112.3	S199 P200 T201 C206 V207	S199-G203 PolarHBondContact O-N 2.97Å; P200-G203 CarbonylContact O-C 3.58Å; P200-G203 WeakPolarHBondContact O-CA 3.3Å; P200-G203 PolarHBondContact O-N 3.39Å; T201-G203 VanDerWaalsContact C-N 3.3Å; T201-G203 PolarHBondContact O-N 3.01Å; G203-C206 WeakPolarHBondContact O-CB 3.2Å; G203-C206 PolarHBondContact O-N 2.71Å; G203-V207 WeakPolarHBondContact O-CG2 3.46Å; G203-V207 PolarHBondContact O-N 2.84Å
204	V	93.4	Very high	90.1	Very high	71 Å²	71	81 Å²	81	43%	0.43	41%	0.414	S	S	.	.	H	α-helix	trans	-61.8	-47.6	176.3	174.9	0	0	0	0	111.4	L125 P200 T201 C206 V207 I208	L125-V204 HydrophobicContact CD1-CG2 3.95Å; P200-V204 PolarHBondContact O-N 3.09Å; T201-V204 PolarHBondContact O-N 2.95Å; V204-C206 VanDerWaalsContact C-N 3.29Å; V204-C206 PolarHBondContact O-N 3.33Å; V204-V207 PolarHBondContact O-N 3.42Å; V204-V207 VanDerWaalsContact O-N 3.14Å; V204-I208 HydrophobicContact CG1-CD1 3.99Å; V204-I208 WeakPolarHBondContact O-CG1 3.39Å; V204-I208 PolarHBondContact O-N 2.86Å
205	V	94.9	Very high	90.9	Very high	81 Å²	81	74.1 Å²	74.1	49%	0.491	38%	0.381	S	S	.	.	H	α-helix	trans	-58.7	-42.1	175.1	173.5	0	0	0	0	111.2	T201 V207 I208 L209	T201-V205 WeakPolarHBondContact O-CG2 3.24Å; T201-V205 PolarHBondContact O-N 2.99Å; V205-V207 PolarHBondContact O-N 3.15Å; V205-I208 PolarHBondContact O-N 3.32Å; V205-L209 HydrophobicContact CG1-CD1 4.07Å; V205-L209 WeakPolarHBondContact O-CG 3.3Å; V205-L209 PolarHBondContact O-N 3.33Å
206	C	94.8	Very high	91.6	Very high	35 Å²	35	69.7 Å²	69.7	24%	0.236	38%	0.375	C	S	.	.	H	α-helix	trans	-63.6	-39.3	176.3	-172.4	0	0	0	0	112.5	F126 R202 G203 V204 L209 I210	F126-C206 HydrophobicContact CE1-CB 4.01Å; F126-C206 HydrophobicContact CZ-CB 3.96Å; R202-C206 VanDerWaalsContact O-CB 3.27Å; R202-C206 WeakPolarHBondContact O-CB 3.27Å; R202-C206 PolarHBondContact O-N 2.92Å; G203-C206 WeakPolarHBondContact O-CB 3.2Å; G203-C206 PolarHBondContact O-N 2.71Å; V204-C206 VanDerWaalsContact C-N 3.29Å; V204-C206 PolarHBondContact O-N 3.33Å; C206-L209 PolarHBondContact O-N 2.92Å; C206-I210 WeakPolarHBondContact O-CD1 3.44Å; C206-I210 WeakPolarHBondContact O-CG1 3.45Å; C206-I210 PolarHBondContact O-N 2.93Å
207	V	96.2	Very high	92.4	Very high	25 Å²	25	68.3 Å²	68.3	15%	0.152	36%	0.358	C	S	.	.	H	α-helix	trans	-62.9	-45.9	173.5	167.6	0	0	0	0	111.4	F126 N129 G203 V204 V205 L209 I210 W211	F126-V207 HydrophobicContact CD1-CG2 3.78Å; F126-V207 HydrophobicContact CE1-CG2 3.86Å; N129-V207 HydrophobicContact CB-CG2 4.29Å; N129-V207 WeakPolarHBondContact OD1-CG1 3.21Å; G203-V207 WeakPolarHBondContact O-CG2 3.46Å; G203-V207 PolarHBondContact O-N 2.84Å; V204-V207 PolarHBondContact O-N 3.42Å; V204-V207 VanDerWaalsContact O-N 3.14Å; V205-V207 PolarHBondContact O-N 3.15Å; V207-L209 VanDerWaalsContact C-N 3.34Å; V207-L209 PolarHBondContact O-N 3.38Å; V207-I210 WeakPolarHBondContact O-CB 3.5Å; V207-I210 PolarHBondContact O-N 3.48Å; V207-I210 VanDerWaalsContact O-N 3.16Å; V207-W211 VanDerWaalsContact O-CD1 3.29Å; V207-W211 PolarHBondContact O-N 3.09Å
208	I	96.8	Very high	93	Very high	98 Å²	98	59.4 Å²	59.4	50%	0.503	32%	0.324	S	S	.	.	H	α-helix	trans	-59	-46.7	177.8	-66.7	165.5	0	0	0	110.5	V204 V205 I210 W211 V212	V204-I208 HydrophobicContact CG1-CD1 3.99Å; V204-I208 WeakPolarHBondContact O-CG1 3.39Å; V204-I208 PolarHBondContact O-N 2.86Å; V205-I208 PolarHBondContact O-N 3.32Å; I208-I210 VanDerWaalsContact C-N 3.33Å; I208-I210 PolarHBondContact O-N 2.88Å; I208-W211 PolarHBondContact O-N 2.93Å; I208-V212 HydrophobicContact CG2-CG2 4.49Å; I208-V212 WeakPolarHBondContact O-CG2 3.48Å; I208-V212 PolarHBondContact O-N 3.45Å
209	L	96.4	Very high	93.5	Very high	97 Å²	97	61.7 Å²	61.7	51%	0.508	34%	0.337	S	S	.	.	H	α-helix	trans	-60.9	-39.9	176.3	-69.5	170.2	0	0	0	112.3	V205 C206 V207 V212 M213	V205-L209 HydrophobicContact CG1-CD1 4.07Å; V205-L209 WeakPolarHBondContact O-CG 3.3Å; V205-L209 PolarHBondContact O-N 3.33Å; C206-L209 PolarHBondContact O-N 2.92Å; V207-L209 VanDerWaalsContact C-N 3.34Å; V207-L209 PolarHBondContact O-N 3.38Å; L209-V212 PolarHBondContact O-N 3.04Å; L209-M213 HydrophobicContact CB-CE 4.4Å; L209-M213 WeakPolarHBondContact O-CB 3.44Å; L209-M213 WeakPolarHBondContact O-CE 3.33Å; L209-M213 VanDerWaalsContact O-CG 3.32Å; L209-M213 WeakPolarHBondContact O-CG 3.3Å; L209-M213 PolarHBondContact O-N 3.21Å
210	I	97	Very high	93.6	Very high	5 Å²	5	61.4 Å²	61.4	3%	0.026	33%	0.334	C	S	.	.	H	α-helix	trans	-60.1	-46.8	175.1	-73	163.3	0	0	0	111.1	F126 V174 L177 A181 C206 V207 I208 A214	F126-I210 HydrophobicContact CE1-CD1 4.37Å; V174-I210 HydrophobicContact CB-CG2 4.3Å; V174-I210 HydrophobicContact CG1-CG2 4.07Å; V174-I210 HydrophobicContact CG2-CG2 4.31Å; L177-I210 HydrophobicContact CB-CG1 4.1Å; L177-I210 HydrophobicContact CB-CG2 3.92Å; L177-I210 HydrophobicContact CD1-CG2 4.47Å; A181-I210 HydrophobicContact CB-CD1 4.11Å; C206-I210 WeakPolarHBondContact O-CD1 3.44Å; C206-I210 WeakPolarHBondContact O-CG1 3.45Å; C206-I210 PolarHBondContact O-N 2.93Å; V207-I210 WeakPolarHBondContact O-CB 3.5Å; V207-I210 PolarHBondContact O-N 3.48Å; V207-I210 VanDerWaalsContact O-N 3.16Å; I208-I210 VanDerWaalsContact C-N 3.33Å; I208-I210 PolarHBondContact O-N 2.88Å; I210-A214 WeakPolarHBondContact O-CB 3.14Å; I210-A214 PolarHBondContact O-N 3.39Å
211	W	97.7	Very high	93.6	Very high	64 Å²	64	57.8 Å²	57.8	24%	0.242	31%	0.31	C	S	.	.	H	α-helix	trans	-66	-39.7	178.6	-81.6	97.4	0	0	0	112.9	N129 V132 L136 V174 V207 I208 S215	N129-W211 PolarHBondContact OD1-NE1 3.33Å; V132-W211 HydrophobicContact CG1-CZ2 4.19Å; L136-W211 HydrophobicContact CD2-CH2 3.94Å; L136-W211 HydrophobicContact CD2-CZ3 4.07Å; V174-W211 HydrophobicContact CG1-CZ2 4.01Å; V174-W211 HydrophobicContact CG2-CD2 3.78Å; V174-W211 HydrophobicContact CG2-CE3 3.73Å; V174-W211 HydrophobicContact CG2-CG 4.33Å; V174-W211 HydrophobicContact CG2-CH2 4.22Å; V174-W211 HydrophobicContact CG2-CZ2 4.26Å; V174-W211 HydrophobicContact CG2-CZ3 3.96Å; V207-W211 VanDerWaalsContact O-CD1 3.29Å; V207-W211 PolarHBondContact O-N 3.09Å; I208-W211 PolarHBondContact O-N 2.93Å; W211-S215 VanDerWaalsContact O-CB 3.23Å; W211-S215 WeakPolarHBondContact O-CB 3.3Å; W211-S215 PolarHBondContact O-N 3.06Å; W211-S215 PolarHBondContact O-OG 3.07Å
212	V	97.2	Very high	93.6	Very high	81 Å²	81	53.3 Å²	53.3	49%	0.491	28%	0.283	S	S	.	.	H	α-helix	trans	-63.3	-53.8	175.6	172.2	0	0	0	0	110.3	I208 L209 A214 S215 C216	I208-V212 HydrophobicContact CG2-CG2 4.49Å; I208-V212 WeakPolarHBondContact O-CG2 3.48Å; I208-V212 PolarHBondContact O-N 3.45Å; L209-V212 PolarHBondContact O-N 3.04Å; V212-A214 PolarHBondContact O-N 2.78Å; V212-S215 PolarHBondContact O-N 2.82Å; V212-C216 PolarHBondContact O-N 2.92Å; V212-C216 PolarHBondContact O-SG 2.87Å
213	M	94.8	Very high	93.5	Very high	83 Å²	83	51 Å²	51	41%	0.409	28%	0.281	S	S	.	.	H	α-helix	trans	-57.9	-49.6	178.8	-70.9	-176.4	-64.8	0	0	111.8	L177 L209 S215 C216 F217	L177-M213 HydrophobicContact CD1-CB 4.22Å; L177-M213 HydrophobicContact CD1-CE 4.47Å; L209-M213 HydrophobicContact CB-CE 4.4Å; L209-M213 WeakPolarHBondContact O-CB 3.44Å; L209-M213 WeakPolarHBondContact O-CE 3.33Å; L209-M213 VanDerWaalsContact O-CG 3.32Å; L209-M213 WeakPolarHBondContact O-CG 3.3Å; L209-M213 PolarHBondContact O-N 3.21Å; M213-S215 VanDerWaalsContact C-N 3.31Å; M213-S215 PolarHBondContact O-N 2.96Å; M213-C216 PolarHBondContact O-N 3.41Å; M213-F217 WeakPolarHBondContact O-CD2 3.16Å; M213-F217 PolarHBondContact O-N 3.1Å; M213-F217 VanDerWaalsContact O-N 3.09Å
214	A	96.1	Very high	93.2	Very high	0 Å²	0	54.8 Å²	54.8	0%	0	30%	0.296	C	S	.	.	H	α-helix	trans	-57.8	-43.3	178.3	0	0	0	0	0	112.2	H173 V174 L177 I210 V212 S218	H173-A214 HydrophobicContact CB-CB 3.63Å; V174-A214 HydrophobicContact CB-CB 4.44Å; V174-A214 HydrophobicContact CG2-CB 3.49Å; V174-A214 VanDerWaalsContact CG2-CB 3.49Å; L177-A214 HydrophobicContact CD1-CB 4.44Å; I210-A214 WeakPolarHBondContact O-CB 3.14Å; I210-A214 PolarHBondContact O-N 3.39Å; V212-A214 PolarHBondContact O-N 2.78Å; A214-S218 VanDerWaalsContact O-CB 3.3Å; A214-S218 WeakPolarHBondContact O-CB 3.5Å; A214-S218 PolarHBondContact O-N 3.48Å; A214-S218 PolarHBondContact O-OG 3.26Å
215	S	95.6	Very high	92.8	Very high	31 Å²	31	52 Å²	52	22%	0.217	28%	0.279	C	S	.	.	H	α-helix	trans	-65.8	-45.1	178.1	-59.3	0	0	0	0	111.8	W211 V212 M213 F217 S218 L219	W211-S215 VanDerWaalsContact O-CB 3.23Å; W211-S215 WeakPolarHBondContact O-CB 3.3Å; W211-S215 PolarHBondContact O-N 3.06Å; W211-S215 PolarHBondContact O-OG 3.07Å; V212-S215 PolarHBondContact O-N 2.82Å; M213-S215 VanDerWaalsContact C-N 3.31Å; M213-S215 PolarHBondContact O-N 2.96Å; S215-F217 VanDerWaalsContact C-N 3.33Å; S215-F217 PolarHBondContact O-N 2.97Å; S215-S218 PolarHBondContact O-N 3.29Å; S215-S218 VanDerWaalsContact O-N 3.15Å; S215-L219 VanDerWaalsContact O-CG 3.3Å; S215-L219 WeakPolarHBondContact O-CG 3.47Å; S215-L219 PolarHBondContact O-N 2.83Å
216	C	93.6	Very high	92.1	Very high	76 Å²	76	52.5 Å²	52.5	51%	0.514	27%	0.274	S	S	.	.	H	α-helix	trans	-57.1	-43.9	177.3	-69.8	0	0	0	0	112.3	V212 M213 P220	V212-C216 PolarHBondContact O-N 2.92Å; V212-C216 PolarHBondContact O-SG 2.87Å; M213-C216 PolarHBondContact O-N 3.41Å; C216-P220 WeakPolarHBondContact O-CD 3.31Å
217	F	91	Very high	91.6	Very high	82 Å²	82	52.9 Å²	52.9	36%	0.36	27%	0.274	S	S	.	.	H	α-helix	trans	-75.8	-24.8	177.1	-70.6	-67.1	0	0	0	114	M213 S215 H221 L263 L264	M213-F217 WeakPolarHBondContact O-CD2 3.16Å; M213-F217 PolarHBondContact O-N 3.1Å; M213-F217 VanDerWaalsContact O-N 3.09Å; S215-F217 VanDerWaalsContact C-N 3.33Å; S215-F217 PolarHBondContact O-N 2.97Å; F217-H221 PolarHBondContact O-CD2 3.16Å; F217-L263 HydrophobicContact CE1-CD1 4.35Å; F217-L264 HydrophobicContact CB-CD1 3.36Å; F217-L264 HydrophobicContact CD1-CD1 4.06Å; F217-L264 HydrophobicContact CD2-CD1 3.68Å; F217-L264 HydrophobicContact CD2-CD2 3.84Å; F217-L264 HydrophobicContact CD2-CG 4.32Å; F217-L264 HydrophobicContact CE2-CD1 4.46Å; F217-L264 HydrophobicContact CE2-CD2 4.03Å; F217-L264 HydrophobicContact CG-CD1 3.46Å; F217-L264 VanDerWaalsContact CG-CD1 3.46Å; F217-L264 HydrophobicContact CG-CD2 4.45Å; F217-L264 HydrophobicContact CG-CG 4.45Å
218	S	92.7	Very high	90.8	Very high	0 Å²	0	54.6 Å²	54.6	0%	0	28%	0.282	C	S	.	.	H	α-helix	trans	-86.1	-14.7	176.8	-62.8	0	0	0	0	114.4	Y169 C170 H173 A214 S215 A222	Y169-S218 VanDerWaalsContact CB-OG 3.27Å; Y169-S218 WeakPolarHBondContact CB-OG 3.22Å; Y169-S218 PolarHBondContact O-OG 3.22Å; C170-S218 VanDerWaalsContact CA-OG 3.24Å; C170-S218 WeakPolarHBondContact CA-OG 3.35Å; C170-S218 PolarHBondContact N-OG 3.33Å; H173-S218 PolarHBondContact ND1-OG 3.33Å; A214-S218 VanDerWaalsContact O-CB 3.3Å; A214-S218 WeakPolarHBondContact O-CB 3.5Å; A214-S218 PolarHBondContact O-N 3.48Å; A214-S218 PolarHBondContact O-OG 3.26Å; S215-S218 PolarHBondContact O-N 3.29Å; S215-S218 VanDerWaalsContact O-N 3.15Å; S218-A222 PolarHBondContact O-N 2.99Å
219	L	91.4	Very high	89.8	Confident	81 Å²	81	54.5 Å²	54.5	42%	0.424	29%	0.286	S	S	.	.	H	α-helix	trans	-65.1	-46.4	-179.5	-87.4	167.4	0	0	0	113.8	F166 S215 H221 A222 I223	F166-L219 HydrophobicContact CE2-CD2 4.32Å; F166-L219 HydrophobicContact CE2-CG 4.17Å; S215-L219 VanDerWaalsContact O-CG 3.3Å; S215-L219 WeakPolarHBondContact O-CG 3.47Å; S215-L219 PolarHBondContact O-N 2.83Å; L219-H221 VanDerWaalsContact C-N 3.3Å; L219-H221 PolarHBondContact O-N 3.26Å; L219-A222 WeakPolarHBondContact O-CB 3.32Å; L219-A222 PolarHBondContact O-N 3.33Å; L219-I223 HydrophobicContact CB-CD1 4.36Å; L219-I223 VanDerWaalsContact O-CG1 3.3Å; L219-I223 WeakPolarHBondContact O-CG1 3.46Å; L219-I223 PolarHBondContact O-N 2.96Å
220	P	89.4	Confident	88.7	Confident	42 Å²	42	53.3 Å²	53.3	27%	0.273	28%	0.277	S	S	.	.	H	α-helix	trans	-55.3	-45.8	176.9	-26.9	35.2	0	0	0	112.4	C216 A222 I223 Y224	C216-P220 WeakPolarHBondContact O-CD 3.31Å; P220-A222 PolarHBondContact O-N 3.37Å; P220-I223 PolarHBondContact O-N 3.3Å; P220-Y224 HydrophobicContact CB-CD2 4.27Å; P220-Y224 HydrophobicContact CB-CE2 4.2Å; P220-Y224 WeakPolarHBondContact O-CD2 3.32Å; P220-Y224 PolarHBondContact O-N 3.05Å
221	H	86.1	Confident	87.4	Confident	3 Å²	3	58.5 Å²	58.5	1%	0.014	31%	0.308	C	S	.	.	H	α-helix	trans	-60.8	-22.3	176	-70.9	-67.7	0	0	0	114.8	R165 Y169 F217 L219 D257 T260	R165-H221 VanDerWaalsContact CG-O 3.27Å; R165-H221 WeakPolarHBondContact CG-O 3.49Å; Y169-H221 HydrophobicContact CD2-CB 3.44Å; Y169-H221 VanDerWaalsContact CD2-CB 3.44Å; Y169-H221 AromaticContact CD2-CD2 3.98Å; Y169-H221 AromaticContact CD2-CG 3.59Å; Y169-H221 AromaticContact CE1-CE1 3.94Å; Y169-H221 AromaticContact CE1-NE2 3.92Å; Y169-H221 HydrophobicContact CE2-CB 3.42Å; Y169-H221 VanDerWaalsContact CE2-CB 3.42Å; Y169-H221 AromaticContact CE2-CD2 3.89Å; Y169-H221 AromaticContact CE2-CE1 3.91Å; Y169-H221 AromaticContact CE2-CG 3.27Å; Y169-H221 AromaticContact CE2-ND1 3.31Å; Y169-H221 VanDerWaalsContact CE2-ND1 3.31Å; Y169-H221 WeakPolarHBondContact CE2-ND1 3.37Å; Y169-H221 HydrophobicContact CG-CB 4.31Å; Y169-H221 AromaticContact CZ-CD2 3.99Å; Y169-H221 AromaticContact CZ-CE1 3.49Å; Y169-H221 VanDerWaalsContact CZ-CE1 3.49Å; Y169-H221 AromaticContact CZ-CG 3.66Å; Y169-H221 AromaticContact CZ-ND1 3.36Å; Y169-H221 AromaticContact CZ-NE2 3.88Å; Y169-H221 PolarHBondContact OH-CE1 2.89Å; Y169-H221 PolarHBondContact OH-ND1 2.89Å; F217-H221 PolarHBondContact O-CD2 3.16Å; L219-H221 VanDerWaalsContact C-N 3.3Å; L219-H221 PolarHBondContact O-N 3.26Å; H221-D257 IonicContact CE1-OD1 3.21Å; H221-D257 PolarHBondContact CE1-OD1 3.17Å; H221-D257 IonicContact ND1-OD1 3.97Å; H221-T260 PolarHBondContact NE2-OG1 3.4Å
222	A	89	Confident	85.8	Confident	9 Å²	9	61 Å²	61	7%	0.074	32%	0.318	C	S	.	.	H	α-helix	trans	-91.8	-36.3	175.5	0	0	0	0	0	112.3	H162 F166 S218 L219 P220	H162-A222 PolarHBondContact ND1-O 2.85Å; F166-A222 HydrophobicContact CB-CB 3.67Å; F166-A222 HydrophobicContact CD2-CB 4.11Å; F166-A222 HydrophobicContact CG-CB 4.36Å; S218-A222 PolarHBondContact O-N 2.99Å; L219-A222 WeakPolarHBondContact O-CB 3.32Å; L219-A222 PolarHBondContact O-N 3.33Å; P220-A222 PolarHBondContact O-N 3.37Å
223	I	88.2	Confident	84.3	Confident	107 Å²	107	60.6 Å²	60.6	55%	0.549	32%	0.319	S	S	.	.	H	α-helix	trans	-69.9	-46.5	-179.5	-68.8	163.6	0	0	0	110.7	L219 P220 Q225	L219-I223 HydrophobicContact CB-CD1 4.36Å; L219-I223 VanDerWaalsContact O-CG1 3.3Å; L219-I223 WeakPolarHBondContact O-CG1 3.46Å; L219-I223 PolarHBondContact O-N 2.96Å; P220-I223 PolarHBondContact O-N 3.3Å; I223-Q225 PolarHBondContact O-N 3.09Å
224	Y	84.9	Confident	82.6	Confident	80 Å²	80	66.5 Å²	66.5	31%	0.314	34%	0.342	S	S	.	.	T	Hydrogen-bonded Turn	trans	-80.1	5.9	178.6	-59	-57.3	0	0	0	114	P220 P243 D244 F245 P246 I256	P220-Y224 HydrophobicContact CB-CD2 4.27Å; P220-Y224 HydrophobicContact CB-CE2 4.2Å; P220-Y224 WeakPolarHBondContact O-CD2 3.32Å; P220-Y224 PolarHBondContact O-N 3.05Å; Y224-P243 CarbonylContact O-C 3.59Å; Y224-P243 WeakPolarHBondContact O-CA 3.5Å; Y224-D244 PolarHBondContact O-N 3.21Å; Y224-F245 HydrophobicContact CD1-CD1 4.33Å; Y224-F245 AromaticContact CD2-CD1 3.55Å; Y224-F245 HydrophobicContact CD2-CD1 3.55Å; Y224-F245 AromaticContact CD2-CE1 3.51Å; Y224-F245 HydrophobicContact CD2-CE1 3.51Å; Y224-F245 HydrophobicContact CE2-CD1 4.25Å; Y224-F245 HydrophobicContact CE2-CE1 4.38Å; Y224-F245 AromaticContact CG-CD1 3.6Å; Y224-F245 HydrophobicContact CG-CD1 3.6Å; Y224-F245 AromaticContact CG-CE1 3.84Å; Y224-F245 HydrophobicContact CG-CE1 3.84Å; Y224-F245 HydrophobicContact CG-CG 4.37Å; Y224-P246 VanDerWaalsContact CE1-CD 3.48Å; Y224-P246 HydrophobicContact CE1-CG 4Å; Y224-I256 HydrophobicContact CD2-CD1 4.37Å; Y224-I256 HydrophobicContact CE2-CD1 4.07Å
225	Q	84.1	Confident	80.8	Confident	13 Å²	13	75.2 Å²	75.2	6%	0.061	38%	0.383	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-84.9	117.6	170	-168.6	82.7	-3.8	0	0	108.9	H162 R165 I223 C241 V242	H162-Q225 PolarHBondContact CE1-O 3.48Å; H162-Q225 PolarHBondContact ND1-O 3.48Å; H162-Q225 VanDerWaalsContact ND1-O 3.12Å; R165-Q225 HydrophobicContact CB-CB 4.4Å; R165-Q225 HydrophobicContact CB-CG 4.08Å; R165-Q225 HydrophobicContact CG-CB 4.26Å; R165-Q225 HydrophobicContact CG-CG 4.11Å; I223-Q225 PolarHBondContact O-N 3.09Å; Q225-C241 PolarHBondContact NE2-O 3.28Å; Q225-C241 PolarHBondContact NE2-SG 2.98Å; Q225-V242 CarbonylContact C-O 3.55Å
226	K	81.2	Confident	79.1	Confident	91 Å²	91	80.6 Å²	80.6	40%	0.396	40%	0.403	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-112.2	158.4	176.2	-64	-168.6	-134.3	150.1	0	112.1	C241 V242 D244	K226-C241 WeakPolarHBondContact O-CA 3.31Å; K226-V242 PolarHBondContact N-O 3.15Å; K226-V242 PolarHBondContact O-N 3.41Å; K226-V242 VanDerWaalsContact O-O 3.11Å; K226-D244 HydrophobicContact CB-CB 3.96Å; K226-D244 HydrophobicContact CD-CB 3.99Å; K226-D244 WeakPolarHBondContact CD-OD2 3.28Å; K226-D244 WeakPolarHBondContact CE-O 3.21Å; K226-D244 WeakPolarHBondContact CE-OD2 3.22Å; K226-D244 HydrophobicContact CG-CB 3.95Å; K226-D244 IonicContact NZ-OD1 2.88Å; K226-D244 PolarHBondContact NZ-OD1 2.98Å; K226-D244 IonicContact NZ-OD2 2.71Å; K226-D244 PolarHBondContact NZ-OD2 3Å
227	L	83.6	Confident	78.2	Confident	42 Å²	42	81.4 Å²	81.4	22%	0.22	41%	0.405	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-105.6	100.2	175.2	-179.8	63.8	0	0	0	108.4	W154 K158 L240 C241	W154-L227 HydrophobicContact CB-CD1 4.02Å; W154-L227 HydrophobicContact CG-CD1 3.96Å; K158-L227 HydrophobicContact CB-CD2 4.28Å; L227-L240 WeakPolarHBondContact CA-O 3.36Å; L227-C241 HydrophobicContact CD1-CB 4.44Å
228	L	79.4	Confident	77.5	Confident	62 Å²	62	82.2 Å²	82.2	33%	0.325	41%	0.406	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-86.1	142.2	175.8	-55.8	-177.4	0	0	0	109.8	F230 S239 L240 V242	L228-F230 HydrophobicContact CB-CD2 4.4Å; L228-F230 HydrophobicContact CB-CE2 3.55Å; L228-F230 HydrophobicContact CB-CZ 3.88Å; L228-F230 HydrophobicContact CD1-CE2 4.22Å; L228-F230 HydrophobicContact CD1-CZ 3.97Å; L228-S239 CarbonylContact O-C 3.37Å; L228-S239 VanDerWaalsContact O-CA 3.3Å; L228-S239 WeakPolarHBondContact O-CA 3.13Å; L228-L240 PolarHBondContact N-O 3.08Å; L228-L240 PolarHBondContact O-N 3Å; L228-V242 HydrophobicContact CD1-CG2 3.67Å; L228-V242 HydrophobicContact CG-CG2 3.92Å
229	T	76	Confident	76.9	Confident	95 Å²	95	83.4 Å²	83.4	58%	0.583	41%	0.414	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-126.6	118.2	-177.9	54.7	0	0	0	0	110.7
230	F	73.6	Confident	76.2	Confident	73 Å²	73	83 Å²	83	32%	0.32	41%	0.412	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-118.1	134.2	-175.7	-58.7	-82	0	0	0	110.8	L228 Y232 R238 L240	L228-F230 HydrophobicContact CB-CD2 4.4Å; L228-F230 HydrophobicContact CB-CE2 3.55Å; L228-F230 HydrophobicContact CB-CZ 3.88Å; L228-F230 HydrophobicContact CD1-CE2 4.22Å; L228-F230 HydrophobicContact CD1-CZ 3.97Å; F230-Y232 PolarHBondContact O-N 3.43Å; F230-R238 PolarHBondContact N-O 2.91Å; F230-R238 PolarHBondContact O-N 3.47Å; F230-L240 HydrophobicContact CD2-CD1 4.34Å; F230-L240 HydrophobicContact CE2-CD1 4.22Å
231	V	70.1	Confident	75.8	Confident	113 Å²	113	81.4 Å²	81.4	69%	0.685	40%	0.402	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-80.9	101.3	172.7	-177.3	0	0	0	0	108.3	S233	V231-S233 VanDerWaalsContact CG1-O 3.26Å; V231-S233 WeakPolarHBondContact CG1-O 3.43Å
232	Y	63.4	Low	75.4	Confident	116 Å²	116	83.4 Å²	83.4	46%	0.455	41%	0.414	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-82.5	-21.7	-176.1	-175.3	-105.2	0	0	0	112.8	F230 K236	F230-Y232 PolarHBondContact O-N 3.43Å; Y232-K236 WeakPolarHBondContact CB-O 3.33Å; Y232-K236 PolarHBondContact N-O 2.83Å
233	S	65.6	Low	74.7	Confident	73 Å²	73	85.4 Å²	85.4	51%	0.51	43%	0.426	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-162	171	168	-163.7	0	0	0	0	108.9	V231 E235 K236	V231-S233 VanDerWaalsContact CG1-O 3.26Å; V231-S233 WeakPolarHBondContact CG1-O 3.43Å; S233-E235 PolarHBondContact O-N 2.89Å; S233-K236 PolarHBondContact N-O 3.43Å; S233-K236 PolarHBondContact O-N 3.39Å
234	K	58.7	Low	74.1	Confident	207 Å²	207	82.8 Å²	82.8	90%	0.9	41%	0.413	S	S	*	.	T	Hydrogen-bonded Turn	trans	-52.2	-22.1	-173.2	-71.3	-170.1	174.7	-173.9	0	115.2
235	E	60.1	Low	73.4	Confident	183 Å²	183	79.7 Å²	79.7	86%	0.855	40%	0.402	S	S	*	.	T	Hydrogen-bonded Turn	trans	-125	5.4	-179.2	-62.9	172.5	179.3	0	0	113.8	S233	S233-E235 PolarHBondContact O-N 2.89Å
236	K	59.7	Low	72.5	Confident	144 Å²	144	81.9 Å²	81.9	63%	0.626	42%	0.417	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-132.9	97.7	-172.5	-69.6	-174.6	-179.4	174.5	0	112.6	Y232 S233	Y232-K236 WeakPolarHBondContact CB-O 3.33Å; Y232-K236 PolarHBondContact N-O 2.83Å; S233-K236 PolarHBondContact N-O 3.43Å; S233-K236 PolarHBondContact O-N 3.39Å
237	V	74.4	Confident	71.4	Confident	94 Å²	94	86 Å²	86	57%	0.57	44%	0.438	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-76.7	135.2	166.8	-174.5	0	0	0	0	109.6
238	R	76.1	Confident	70.6	Confident	99 Å²	99	87.9 Å²	87.9	37%	0.374	45%	0.452	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-114.3	140.7	166.7	-75.3	-176.8	173	163.8	-1.4	109.3	F230	F230-R238 PolarHBondContact N-O 2.91Å; F230-R238 PolarHBondContact O-N 3.47Å
239	S	79.9	Confident	69.9	Low	24 Å²	24	87.2 Å²	87.2	17%	0.168	45%	0.453	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-119.1	136.9	178.9	-47.8	0	0	0	0	109.6	S153 W154 L228	S153-S239 CarbonylContact C-O 3.51Å; S153-S239 WeakPolarHBondContact CA-O 3.49Å; S153-S239 PolarHBondContact OG-N 2.88Å; S153-S239 VanDerWaalsContact OG-N 3.15Å; W154-S239 WeakPolarHBondContact CB-O 3.36Å; W154-S239 PolarHBondContact N-O 3.27Å; L228-S239 CarbonylContact O-C 3.37Å; L228-S239 VanDerWaalsContact O-CA 3.3Å; L228-S239 WeakPolarHBondContact O-CA 3.13Å
240	L	76.2	Confident	69.7	Low	72 Å²	72	85.8 Å²	85.8	38%	0.377	44%	0.442	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-126.8	125.1	-178.4	-67.5	175.7	0	0	0	109.9	L227 L228 F230 V242	L227-L240 WeakPolarHBondContact CA-O 3.36Å; L228-L240 PolarHBondContact N-O 3.08Å; L228-L240 PolarHBondContact O-N 3Å; F230-L240 HydrophobicContact CD2-CD1 4.34Å; F230-L240 HydrophobicContact CE2-CD1 4.22Å; L240-V242 HydrophobicContact CB-CG1 4.21Å
241	C	81.4	Confident	69.9	Low	10 Å²	10	86.8 Å²	86.8	7%	0.068	45%	0.454	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-92.7	105.4	174.1	179.7	0	0	0	0	107.9	W154 C161 Q225 K226 L227	W154-C241 HydrophobicContact CB-CB 4.3Å; W154-C241 HydrophobicContact CD2-CB 3.8Å; W154-C241 HydrophobicContact CE3-CB 3.97Å; W154-C241 HydrophobicContact CG-CB 3.93Å; C161-C241 WeakPolarHBondContact CA-SG 3.42Å; C161-C241 HydrophobicContact CB-CB 3.91Å; C161-C241 WeakPolarHBondContact CB-SG 3.18Å; C161-C241 VanDerWaalsContact SG-CA 3.58Å; C161-C241 WeakPolarHBondContact SG-CB 3.31Å; C161-C241 CovalentContact SG-SG 2.03Å; C161-C241 PolarHBondContact SG-SG 2.76Å; Q225-C241 PolarHBondContact NE2-O 3.28Å; Q225-C241 PolarHBondContact NE2-SG 2.98Å; K226-C241 WeakPolarHBondContact O-CA 3.31Å; L227-C241 HydrophobicContact CD1-CB 4.44Å
242	V	77.3	Confident	70.3	Confident	45 Å²	45	87.1 Å²	87.1	27%	0.273	44%	0.444	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-137.3	158.1	-170.7	-67.2	0	0	0	0	111.2	Q225 K226 L228 L240	Q225-V242 CarbonylContact C-O 3.55Å; K226-V242 PolarHBondContact N-O 3.15Å; K226-V242 PolarHBondContact O-N 3.41Å; K226-V242 VanDerWaalsContact O-O 3.11Å; L228-V242 HydrophobicContact CD1-CG2 3.67Å; L228-V242 HydrophobicContact CG-CG2 3.92Å; L240-V242 HydrophobicContact CB-CG1 4.21Å
243	P	73.8	Confident	71	Confident	50 Å²	50	84 Å²	84	33%	0.325	43%	0.431	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-68.2	144.9	168.2	-11.5	27.8	0	0	0	110.7	Y224 F245	Y224-P243 CarbonylContact O-C 3.59Å; Y224-P243 WeakPolarHBondContact O-CA 3.5Å; P243-F245 HydrophobicContact CB-CD2 4.01Å; P243-F245 HydrophobicContact CB-CE2 3.51Å; P243-F245 HydrophobicContact CB-CZ 4.46Å
244	D	75.9	Confident	71.8	Confident	52 Å²	52	84.3 Å²	84.3	28%	0.278	42%	0.424	S	S	.	.			trans	-153.9	90.5	-179.3	179.4	-9.6	0	0	0	107.5	Y224 K226	Y224-D244 PolarHBondContact O-N 3.21Å; K226-D244 HydrophobicContact CB-CB 3.96Å; K226-D244 HydrophobicContact CD-CB 3.99Å; K226-D244 WeakPolarHBondContact CD-OD2 3.28Å; K226-D244 WeakPolarHBondContact CE-O 3.21Å; K226-D244 WeakPolarHBondContact CE-OD2 3.22Å; K226-D244 HydrophobicContact CG-CB 3.95Å; K226-D244 IonicContact NZ-OD1 2.88Å; K226-D244 PolarHBondContact NZ-OD1 2.98Å; K226-D244 IonicContact NZ-OD2 2.71Å; K226-D244 PolarHBondContact NZ-OD2 3Å
245	F	70	Confident	73.1	Confident	15 Å²	15	78 Å²	78	7%	0.066	41%	0.405	C	S	.	.	P	Polyproline II helix	trans	-91.8	149.6	-174.3	-69.5	-91.9	0	0	0	111.2	Y224 P243 S249 W253 I256	Y224-F245 HydrophobicContact CD1-CD1 4.33Å; Y224-F245 AromaticContact CD2-CD1 3.55Å; Y224-F245 HydrophobicContact CD2-CD1 3.55Å; Y224-F245 AromaticContact CD2-CE1 3.51Å; Y224-F245 HydrophobicContact CD2-CE1 3.51Å; Y224-F245 HydrophobicContact CE2-CD1 4.25Å; Y224-F245 HydrophobicContact CE2-CE1 4.38Å; Y224-F245 AromaticContact CG-CD1 3.6Å; Y224-F245 HydrophobicContact CG-CD1 3.6Å; Y224-F245 AromaticContact CG-CE1 3.84Å; Y224-F245 HydrophobicContact CG-CE1 3.84Å; Y224-F245 HydrophobicContact CG-CG 4.37Å; P243-F245 HydrophobicContact CB-CD2 4.01Å; P243-F245 HydrophobicContact CB-CE2 3.51Å; P243-F245 HydrophobicContact CB-CZ 4.46Å; F245-S249 VanDerWaalsContact O-CB 3.28Å; F245-S249 WeakPolarHBondContact O-CB 3.42Å; F245-W253 HydrophobicContact CD2-CB 3.54Å; F245-W253 HydrophobicContact CD2-CD2 4.47Å; F245-W253 AromaticContact CD2-CG 3.73Å; F245-W253 HydrophobicContact CD2-CG 3.73Å; F245-W253 HydrophobicContact CE2-CB 3.64Å; F245-W253 AromaticContact CE2-CD1 3.24Å; F245-W253 HydrophobicContact CE2-CD2 4.19Å; F245-W253 AromaticContact CE2-CG 3.39Å; F245-W253 HydrophobicContact CE2-CG 3.39Å; F245-W253 AromaticContact CE2-NE1 3.96Å; F245-W253 HydrophobicContact CG-CB 4.02Å; F245-W253 HydrophobicContact CZ-CB 4.21Å; F245-W253 AromaticContact CZ-CD1 3.59Å; F245-W253 HydrophobicContact CZ-CG 4.07Å; F245-I256 HydrophobicContact CD1-CD1 4.23Å; F245-I256 HydrophobicContact CE1-CD1 3.85Å
246	P	65.4	Low	74.3	Confident	59 Å²	59	70.9 Å²	70.9	38%	0.383	37%	0.373	S	S	.	.	P	Polyproline II helix	trans	-66	149.6	177.5	29.9	-36.4	0	0	0	111.9	Y224 P248 S249 Y252	Y224-P246 VanDerWaalsContact CE1-CD 3.48Å; Y224-P246 HydrophobicContact CE1-CG 4Å; P246-P248 CarbonylContact O-C 3.58Å; P246-S249 VanDerWaalsContact O-CA 3.27Å; P246-S249 WeakPolarHBondContact O-CA 3.31Å; P246-S249 PolarHBondContact O-N 3.2Å; P246-Y252 HydrophobicContact CG-CD2 4.5Å; P246-Y252 WeakPolarHBondContact O-CD2 3.46Å
247	E	58.1	Low	75.5	Confident	178 Å²	178	64.3 Å²	64.3	83%	0.832	34%	0.344	S	S	*	.	S	Bend	trans	-62.3	140.3	179.3	-74.8	158.7	-148.9	0	0	113
248	P	66.6	Low	76.2	Confident	81 Å²	81	63 Å²	63	53%	0.526	33%	0.334	S	S	.	.	S	Bend	cis	-71	112.9	-9.9	28.8	-34.8	0	0	0	111.9	P246 D250 V251 Y252	P246-P248 CarbonylContact O-C 3.58Å; P248-D250 PolarHBondContact O-N 3.47Å; P248-V251 HydrophobicContact CB-CG2 4.31Å; P248-V251 HydrophobicContact CG-CB 4.35Å; P248-V251 HydrophobicContact CG-CG2 4.41Å; P248-V251 PolarHBondContact O-N 3.38Å; P248-Y252 WeakPolarHBondContact O-CD2 3.31Å; P248-Y252 PolarHBondContact O-N 2.87Å
249	S	65.9	Low	76.8	Confident	48 Å²	48	62.7 Å²	62.7	34%	0.336	34%	0.339	S	S	.	.	H	α-helix	trans	-67.7	-42.5	-163.8	52.9	0	0	0	0	113.1	F245 P246 V251 Y252 W253	F245-S249 VanDerWaalsContact O-CB 3.28Å; F245-S249 WeakPolarHBondContact O-CB 3.42Å; P246-S249 VanDerWaalsContact O-CA 3.27Å; P246-S249 WeakPolarHBondContact O-CA 3.31Å; P246-S249 PolarHBondContact O-N 3.2Å; S249-V251 PolarHBondContact O-N 3.49Å; S249-Y252 PolarHBondContact O-N 3.33Å; S249-W253 VanDerWaalsContact O-CB 3.29Å; S249-W253 WeakPolarHBondContact O-CB 3.47Å; S249-W253 PolarHBondContact O-N 3.06Å
250	D	71.3	Confident	77.2	Confident	65 Å²	65	62.1 Å²	62.1	35%	0.348	34%	0.335	S	S	.	.	H	α-helix	trans	-60.2	-45.3	178	-68.2	-56.6	0	0	0	112.3	P248 W253 Q254 Q335	P248-D250 PolarHBondContact O-N 3.47Å; D250-W253 PolarHBondContact O-N 3.26Å; D250-Q254 VanDerWaalsContact O-CB 3.24Å; D250-Q254 WeakPolarHBondContact O-CB 3.24Å; D250-Q254 PolarHBondContact O-N 3.11Å; D250-Q335 PolarHBondContact OD1-NE2 2.89Å; D250-Q335 PolarHBondContact OD2-NE2 2.89Å; D250-Q335 VanDerWaalsContact OD2-NE2 3.08Å
251	V	77.1	Confident	77.9	Confident	95 Å²	95	60.1 Å²	60.1	58%	0.576	32%	0.323	S	S	*	.	H	α-helix	trans	-65.9	-43.9	-177.6	-177.2	0	0	0	0	110.6	P248 S249 C255	P248-V251 HydrophobicContact CB-CG2 4.31Å; P248-V251 HydrophobicContact CG-CB 4.35Å; P248-V251 HydrophobicContact CG-CG2 4.41Å; P248-V251 PolarHBondContact O-N 3.38Å; S249-V251 PolarHBondContact O-N 3.49Å; V251-C255 WeakPolarHBondContact O-CB 3.38Å; V251-C255 PolarHBondContact O-N 2.89Å
252	Y	79.8	Confident	78.4	Confident	120 Å²	120	63.5 Å²	63.5	47%	0.471	34%	0.339	S	S	.	.	H	α-helix	trans	-66.7	-41.9	175.5	-79.8	-63.7	0	0	0	112.4	P246 P248 S249 I256	P246-Y252 HydrophobicContact CG-CD2 4.5Å; P246-Y252 WeakPolarHBondContact O-CD2 3.46Å; P248-Y252 WeakPolarHBondContact O-CD2 3.31Å; P248-Y252 PolarHBondContact O-N 2.87Å; S249-Y252 PolarHBondContact O-N 3.33Å; Y252-I256 WeakPolarHBondContact O-CB 3.42Å; Y252-I256 WeakPolarHBondContact O-CD1 3.27Å; Y252-I256 VanDerWaalsContact O-CG1 3.23Å; Y252-I256 WeakPolarHBondContact O-CG1 3.29Å; Y252-I256 PolarHBondContact O-N 3.48Å
253	W	77	Confident	78.9	Confident	50 Å²	50	64.2 Å²	64.2	19%	0.189	34%	0.342	C	S	.	.	H	α-helix	trans	-62.6	-54.7	177.8	-178.7	17.8	0	0	0	111.6	F245 S249 D250 C255 I256 D257 L332	F245-W253 HydrophobicContact CD2-CB 3.54Å; F245-W253 HydrophobicContact CD2-CD2 4.47Å; F245-W253 AromaticContact CD2-CG 3.73Å; F245-W253 HydrophobicContact CD2-CG 3.73Å; F245-W253 HydrophobicContact CE2-CB 3.64Å; F245-W253 AromaticContact CE2-CD1 3.24Å; F245-W253 HydrophobicContact CE2-CD2 4.19Å; F245-W253 AromaticContact CE2-CG 3.39Å; F245-W253 HydrophobicContact CE2-CG 3.39Å; F245-W253 AromaticContact CE2-NE1 3.96Å; F245-W253 HydrophobicContact CG-CB 4.02Å; F245-W253 HydrophobicContact CZ-CB 4.21Å; F245-W253 AromaticContact CZ-CD1 3.59Å; F245-W253 HydrophobicContact CZ-CG 4.07Å; S249-W253 VanDerWaalsContact O-CB 3.29Å; S249-W253 WeakPolarHBondContact O-CB 3.47Å; S249-W253 PolarHBondContact O-N 3.06Å; D250-W253 PolarHBondContact O-N 3.26Å; W253-C255 VanDerWaalsContact C-N 3.33Å; W253-C255 PolarHBondContact O-N 3.02Å; W253-I256 PolarHBondContact O-N 3.47Å; W253-D257 PolarHBondContact NE1-OD2 3.28Å; W253-D257 PolarHBondContact O-N 3.49Å; W253-L332 HydrophobicContact CH2-CD2 4.15Å; W253-L332 HydrophobicContact CH2-CG 3.98Å; W253-L332 HydrophobicContact CZ2-CD2 4.4Å; W253-L332 HydrophobicContact CZ2-CG 4.48Å
254	Q	83	Confident	79.6	Confident	80 Å²	80	62.2 Å²	62.2	37%	0.374	33%	0.328	S	S	.	.	H	α-helix	trans	-58.3	-44.7	179.3	-174.2	-174.9	-8.3	0	0	111.2	D250 L258	D250-Q254 VanDerWaalsContact O-CB 3.24Å; D250-Q254 WeakPolarHBondContact O-CB 3.24Å; D250-Q254 PolarHBondContact O-N 3.11Å; Q254-L258 WeakPolarHBondContact O-CB 3.32Å; Q254-L258 PolarHBondContact O-N 3.35Å
255	C	86	Confident	80.3	Confident	74 Å²	74	60.3 Å²	60.3	50%	0.5	32%	0.317	S	S	.	.	H	α-helix	trans	-61.3	-45.6	177.8	-174.7	0	0	0	0	111.7	V251 W253 L259	V251-C255 WeakPolarHBondContact O-CB 3.38Å; V251-C255 PolarHBondContact O-N 2.89Å; W253-C255 VanDerWaalsContact C-N 3.33Å; W253-C255 PolarHBondContact O-N 3.02Å; C255-L259 WeakPolarHBondContact O-CB 3.43Å; C255-L259 PolarHBondContact O-N 2.88Å
256	I	86.4	Confident	81.3	Confident	34 Å²	34	62 Å²	62	17%	0.174	33%	0.329	C	S	.	.	H	α-helix	trans	-67.7	-48.3	-178.5	-71.5	168.7	0	0	0	111.7	Y224 F245 Y252 W253 T260	Y224-I256 HydrophobicContact CD2-CD1 4.37Å; Y224-I256 HydrophobicContact CE2-CD1 4.07Å; F245-I256 HydrophobicContact CD1-CD1 4.23Å; F245-I256 HydrophobicContact CE1-CD1 3.85Å; Y252-I256 WeakPolarHBondContact O-CB 3.42Å; Y252-I256 WeakPolarHBondContact O-CD1 3.27Å; Y252-I256 VanDerWaalsContact O-CG1 3.23Å; Y252-I256 WeakPolarHBondContact O-CG1 3.29Å; Y252-I256 PolarHBondContact O-N 3.48Å; W253-I256 PolarHBondContact O-N 3.47Å; I256-T260 VanDerWaalsContact O-CB 3.24Å; I256-T260 WeakPolarHBondContact O-CB 3.13Å; I256-T260 PolarHBondContact O-N 3.46Å; I256-T260 PolarHBondContact O-OG1 3.05Å
257	D	84.6	Confident	82.6	Confident	5 Å²	5	62.9 Å²	62.9	3%	0.027	33%	0.33	C	S	.	.	H	α-helix	trans	-68.7	-38.5	179.2	-97.3	-42	0	0	0	111.8	Y169 H221 W253 T260 F261 V329	Y169-D257 PolarHBondContact OH-OD1 3.38Å; H221-D257 IonicContact CE1-OD1 3.21Å; H221-D257 PolarHBondContact CE1-OD1 3.17Å; H221-D257 IonicContact ND1-OD1 3.97Å; W253-D257 PolarHBondContact NE1-OD2 3.28Å; W253-D257 PolarHBondContact O-N 3.49Å; D257-T260 PolarHBondContact O-N 2.97Å; D257-F261 WeakPolarHBondContact O-CB 3.34Å; D257-F261 PolarHBondContact O-N 2.91Å; D257-V329 HydrophobicContact CB-CG1 4.2Å; D257-V329 WeakPolarHBondContact OD1-CG1 3.35Å; D257-V329 WeakPolarHBondContact OD2-CG1 3.4Å
258	L	88.3	Confident	84.3	Confident	67 Å²	67	54.7 Å²	54.7	35%	0.351	29%	0.292	S	S	.	.	H	α-helix	trans	-65.7	-45	175.5	-178.6	61.7	0	0	0	112.3	Q254 T260 F261 I262 V330	Q254-L258 WeakPolarHBondContact O-CB 3.32Å; Q254-L258 PolarHBondContact O-N 3.35Å; L258-T260 VanDerWaalsContact C-N 3.33Å; L258-F261 PolarHBondContact O-N 3.44Å; L258-I262 HydrophobicContact CD1-CD1 3.9Å; L258-I262 HydrophobicContact CD1-CG1 4.27Å; L258-I262 HydrophobicContact CG-CD1 3.92Å; L258-I262 WeakPolarHBondContact O-CG1 3.37Å; L258-I262 PolarHBondContact O-N 3.22Å; L258-V330 HydrophobicContact CD1-CG1 4.16Å
259	L	89.6	Confident	85.6	Confident	92 Å²	92	52.1 Å²	52.1	48%	0.482	27%	0.273	S	S	.	.	H	α-helix	trans	-64	-40.7	177	-174.8	67.2	0	0	0	111.1	C255 I262 L263	C255-L259 WeakPolarHBondContact O-CB 3.43Å; C255-L259 PolarHBondContact O-N 2.88Å; L259-I262 PolarHBondContact O-N 3.36Å; L259-L263 HydrophobicContact CD1-CD1 3.67Å; L259-L263 HydrophobicContact CD1-CG 3.93Å; L259-L263 HydrophobicContact CG-CD1 3.86Å; L259-L263 HydrophobicContact CG-CG 4.32Å; L259-L263 WeakPolarHBondContact O-CB 3.32Å; L259-L263 WeakPolarHBondContact O-CG 3.04Å; L259-L263 PolarHBondContact O-N 3.37Å
260	T	87.9	Confident	86.9	Confident	12 Å²	12	55 Å²	55	7%	0.074	28%	0.284	C	S	.	.	H	α-helix	trans	-58.9	-49.6	173.6	-59.4	0	0	0	0	110.5	Y169 H173 H221 I256 D257 L258 I262 L264	Y169-T260 HydrophobicContact CD1-CG2 4.29Å; Y169-T260 HydrophobicContact CE1-CG2 4.2Å; H173-T260 WeakPolarHBondContact NE2-CG2 3.34Å; H221-T260 PolarHBondContact NE2-OG1 3.4Å; I256-T260 VanDerWaalsContact O-CB 3.24Å; I256-T260 WeakPolarHBondContact O-CB 3.13Å; I256-T260 PolarHBondContact O-N 3.46Å; I256-T260 PolarHBondContact O-OG1 3.05Å; D257-T260 PolarHBondContact O-N 2.97Å; L258-T260 VanDerWaalsContact C-N 3.33Å; T260-I262 PolarHBondContact O-N 3.4Å; T260-L264 HydrophobicContact CG2-CD1 4.29Å; T260-L264 WeakPolarHBondContact O-CB 3.39Å; T260-L264 PolarHBondContact O-N 2.95Å
261	F	89.7	Confident	88.1	Confident	31 Å²	31	55 Å²	55	14%	0.136	28%	0.284	C	S	.	.	H	α-helix	trans	-60.4	-46.3	178.3	178.5	-120	0	0	0	112.4	D257 L258 Y265 V266 N326 V330	D257-F261 WeakPolarHBondContact O-CB 3.34Å; D257-F261 PolarHBondContact O-N 2.91Å; L258-F261 PolarHBondContact O-N 3.44Å; F261-Y265 AromaticContact CD2-CD1 3.78Å; F261-Y265 HydrophobicContact CD2-CD1 3.78Å; F261-Y265 HydrophobicContact CD2-CG 4.13Å; F261-Y265 AromaticContact CE2-CD1 3.34Å; F261-Y265 HydrophobicContact CE2-CD1 3.34Å; F261-Y265 AromaticContact CE2-CE1 3.9Å; F261-Y265 HydrophobicContact CE2-CE1 3.9Å; F261-Y265 HydrophobicContact CE2-CG 4.11Å; F261-Y265 HydrophobicContact CZ-CD1 4.21Å; F261-Y265 WeakPolarHBondContact O-CA 3.43Å; F261-Y265 VanDerWaalsContact O-CB 3.31Å; F261-Y265 WeakPolarHBondContact O-CB 3.48Å; F261-Y265 PolarHBondContact O-N 2.9Å; F261-Y265 VanDerWaalsContact O-N 3.14Å; F261-V266 HydrophobicContact CD1-CG2 4.08Å; F261-V266 HydrophobicContact CD2-CG2 4.41Å; F261-V266 HydrophobicContact CE1-CG2 3.77Å; F261-V266 HydrophobicContact CE2-CG2 4.14Å; F261-V266 HydrophobicContact CG-CG2 4.4Å; F261-V266 HydrophobicContact CZ-CG2 3.81Å; F261-V266 PolarHBondContact O-N 3.49Å; F261-N326 HydrophobicContact CD2-CB 3.66Å; F261-N326 HydrophobicContact CE2-CB 3.72Å; F261-V330 HydrophobicContact CB-CG2 3.91Å; F261-V330 HydrophobicContact CD1-CG2 4.21Å; F261-V330 HydrophobicContact CG-CG2 4.08Å
262	I	91.7	Very high	88.8	Confident	80 Å²	80	50.5 Å²	50.5	41%	0.41	26%	0.257	S	S	.	.	I	π-helix	trans	-65.9	-51.8	179.8	-67.9	169.6	0	0	0	110.9	L258 L259 T260 L267	L258-I262 HydrophobicContact CD1-CD1 3.9Å; L258-I262 HydrophobicContact CD1-CG1 4.27Å; L258-I262 HydrophobicContact CG-CD1 3.92Å; L258-I262 WeakPolarHBondContact O-CG1 3.37Å; L258-I262 PolarHBondContact O-N 3.22Å; L259-I262 PolarHBondContact O-N 3.36Å; T260-I262 PolarHBondContact O-N 3.4Å; I262-L267 VanDerWaalsContact O-CB 3.25Å; I262-L267 WeakPolarHBondContact O-CB 3.47Å; I262-L267 PolarHBondContact O-N 2.91Å
263	L	89.5	Confident	89.4	Confident	61 Å²	61	48.6 Å²	48.6	32%	0.319	26%	0.258	S	S	.	.	I	π-helix	trans	-77.4	-29.6	-171.8	-66.2	-175.4	0	0	0	114.4	F217 L259 L267 P268	F217-L263 HydrophobicContact CE1-CD1 4.35Å; L259-L263 HydrophobicContact CD1-CD1 3.67Å; L259-L263 HydrophobicContact CD1-CG 3.93Å; L259-L263 HydrophobicContact CG-CD1 3.86Å; L259-L263 HydrophobicContact CG-CG 4.32Å; L259-L263 WeakPolarHBondContact O-CB 3.32Å; L259-L263 WeakPolarHBondContact O-CG 3.04Å; L259-L263 PolarHBondContact O-N 3.37Å; L263-L267 HydrophobicContact CD2-CD2 4.24Å; L263-P268 VanDerWaalsContact O-CD 3.27Å; L263-P268 WeakPolarHBondContact O-CD 3.41Å; L263-P268 WeakPolarHBondContact O-CG 3.36Å
264	L	87.6	Confident	90.2	Very high	8 Å²	8	49 Å²	49	4%	0.042	27%	0.271	C	S	.	.	I	π-helix	trans	-121.4	-2.1	-168.3	-55.9	170.3	0	0	0	114.2	T176 L177 F217 T260	T176-L264 WeakPolarHBondContact CB-O 3.43Å; T176-L264 WeakPolarHBondContact CG2-O 3.49Å; T176-L264 PolarHBondContact OG1-O 2.78Å; L177-L264 HydrophobicContact CD2-CD2 4.46Å; F217-L264 HydrophobicContact CB-CD1 3.36Å; F217-L264 HydrophobicContact CD1-CD1 4.06Å; F217-L264 HydrophobicContact CD2-CD1 3.68Å; F217-L264 HydrophobicContact CD2-CD2 3.84Å; F217-L264 HydrophobicContact CD2-CG 4.32Å; F217-L264 HydrophobicContact CE2-CD1 4.46Å; F217-L264 HydrophobicContact CE2-CD2 4.03Å; F217-L264 HydrophobicContact CG-CD1 3.46Å; F217-L264 VanDerWaalsContact CG-CD1 3.46Å; F217-L264 HydrophobicContact CG-CD2 4.45Å; F217-L264 HydrophobicContact CG-CG 4.45Å; T260-L264 HydrophobicContact CG2-CD1 4.29Å; T260-L264 WeakPolarHBondContact O-CB 3.39Å; T260-L264 PolarHBondContact O-N 2.95Å
265	Y	89.9	Confident	90.6	Very high	11 Å²	11	45.3 Å²	45.3	4%	0.043	26%	0.255	C	S	.	.	I	π-helix	trans	-123.4	-59.5	169.4	-175.8	-92.3	0	0	0	112	F261 L269 A319 W322 F323	F261-Y265 AromaticContact CD2-CD1 3.78Å; F261-Y265 HydrophobicContact CD2-CD1 3.78Å; F261-Y265 HydrophobicContact CD2-CG 4.13Å; F261-Y265 AromaticContact CE2-CD1 3.34Å; F261-Y265 HydrophobicContact CE2-CD1 3.34Å; F261-Y265 AromaticContact CE2-CE1 3.9Å; F261-Y265 HydrophobicContact CE2-CE1 3.9Å; F261-Y265 HydrophobicContact CE2-CG 4.11Å; F261-Y265 HydrophobicContact CZ-CD1 4.21Å; F261-Y265 WeakPolarHBondContact O-CA 3.43Å; F261-Y265 VanDerWaalsContact O-CB 3.31Å; F261-Y265 WeakPolarHBondContact O-CB 3.48Å; F261-Y265 PolarHBondContact O-N 2.9Å; F261-Y265 VanDerWaalsContact O-N 3.14Å; Y265-L269 HydrophobicContact CD1-CD1 4.08Å; Y265-L269 HydrophobicContact CD2-CD1 4.29Å; Y265-L269 HydrophobicContact CE1-CD1 3.56Å; Y265-L269 HydrophobicContact CE2-CD1 3.79Å; Y265-L269 HydrophobicContact CG-CD1 4.4Å; Y265-L269 WeakPolarHBondContact O-CB 3.39Å; Y265-L269 VanDerWaalsContact O-CG 3.27Å; Y265-L269 WeakPolarHBondContact O-CG 3.49Å; Y265-L269 PolarHBondContact O-N 2.84Å; Y265-L269 WeakPolarHBondContact OH-CD1 3.28Å; Y265-A319 VanDerWaalsContact OH-CA 3.32Å; Y265-A319 WeakPolarHBondContact OH-CA 3.24Å; Y265-A319 PolarHBondContact OH-O 3.21Å; Y265-W322 HydrophobicContact CE2-CB 4Å; Y265-F323 HydrophobicContact CE1-CD2 4.14Å; Y265-F323 WeakPolarHBondContact OH-CB 3.34Å
266	V	92.4	Very high	90.8	Very high	51 Å²	51	42.4 Å²	42.4	31%	0.309	23%	0.233	S	C	.	.	I	π-helix	trans	-68.5	-57.3	-175.3	-178.7	0	0	0	0	112.4	F261 L269 L270	F261-V266 HydrophobicContact CD1-CG2 4.08Å; F261-V266 HydrophobicContact CD2-CG2 4.41Å; F261-V266 HydrophobicContact CE1-CG2 3.77Å; F261-V266 HydrophobicContact CE2-CG2 4.14Å; F261-V266 HydrophobicContact CG-CG2 4.4Å; F261-V266 HydrophobicContact CZ-CG2 3.81Å; F261-V266 PolarHBondContact O-N 3.49Å; V266-L269 PolarHBondContact O-N 3.12Å; V266-L269 VanDerWaalsContact O-N 3.14Å; V266-L270 HydrophobicContact CG1-CD1 4.01Å; V266-L270 HydrophobicContact CG1-CG 4.38Å; V266-L270 WeakPolarHBondContact O-CG 3.42Å; V266-L270 PolarHBondContact O-N 2.8Å
267	L	93.1	Very high	90.9	Very high	78 Å²	78	43.3 Å²	43.3	41%	0.408	24%	0.243	S	C	.	.	H	α-helix	trans	-57.1	-45.4	-178.4	170.5	65.3	0	0	0	112.8	I262 L263 L269 L270 I271	I262-L267 VanDerWaalsContact O-CB 3.25Å; I262-L267 WeakPolarHBondContact O-CB 3.47Å; I262-L267 PolarHBondContact O-N 2.91Å; L263-L267 HydrophobicContact CD2-CD2 4.24Å; L267-L269 PolarHBondContact O-N 3.3Å; L267-L270 PolarHBondContact O-N 3.18Å; L267-I271 HydrophobicContact CD1-CD1 3.93Å; L267-I271 HydrophobicContact CD1-CG1 4.21Å; L267-I271 HydrophobicContact CG-CD1 3.99Å; L267-I271 VanDerWaalsContact O-CG1 3.31Å; L267-I271 WeakPolarHBondContact O-CG1 3.34Å; L267-I271 PolarHBondContact O-N 3.32Å
268	P	93.4	Very high	91.2	Very high	5 Å²	5	45.2 Å²	45.2	3%	0.032	26%	0.255	C	S	.	.	H	α-helix	trans	-59.9	-42.4	173.9	-29	38.8	0	0	0	113.6	T176 T180 L263 L270 I271 I272	T176-P268 HydrophobicContact CG2-CB 3.42Å; T176-P268 VanDerWaalsContact CG2-CB 3.42Å; T176-P268 HydrophobicContact CG2-CG 3.98Å; T180-P268 WeakPolarHBondContact OG1-CB 3.34Å; L263-P268 VanDerWaalsContact O-CD 3.27Å; L263-P268 WeakPolarHBondContact O-CD 3.41Å; L263-P268 WeakPolarHBondContact O-CG 3.36Å; P268-L270 VanDerWaalsContact C-N 3.35Å; P268-L270 PolarHBondContact O-N 2.9Å; P268-I271 PolarHBondContact O-N 3.18Å; P268-I272 WeakPolarHBondContact O-CB 3.36Å; P268-I272 WeakPolarHBondContact O-CD1 3.27Å; P268-I272 WeakPolarHBondContact O-CG1 3.19Å; P268-I272 PolarHBondContact O-N 2.99Å
269	L	92.7	Very high	91.1	Very high	27 Å²	27	42 Å²	42	14%	0.141	24%	0.238	C	C	.	.	H	α-helix	trans	-65.6	-36.4	177.2	-73.6	174.7	0	0	0	112.2	Y265 V266 L267 I272 T273 V315 A319	Y265-L269 HydrophobicContact CD1-CD1 4.08Å; Y265-L269 HydrophobicContact CD2-CD1 4.29Å; Y265-L269 HydrophobicContact CE1-CD1 3.56Å; Y265-L269 HydrophobicContact CE2-CD1 3.79Å; Y265-L269 HydrophobicContact CG-CD1 4.4Å; Y265-L269 WeakPolarHBondContact O-CB 3.39Å; Y265-L269 VanDerWaalsContact O-CG 3.27Å; Y265-L269 WeakPolarHBondContact O-CG 3.49Å; Y265-L269 PolarHBondContact O-N 2.84Å; Y265-L269 WeakPolarHBondContact OH-CD1 3.28Å; V266-L269 PolarHBondContact O-N 3.12Å; V266-L269 VanDerWaalsContact O-N 3.14Å; L267-L269 PolarHBondContact O-N 3.3Å; L269-I272 HydrophobicContact CD2-CD1 4.47Å; L269-T273 VanDerWaalsContact O-CB 3.22Å; L269-T273 WeakPolarHBondContact O-CB 3.47Å; L269-T273 PolarHBondContact O-N 2.96Å; L269-T273 PolarHBondContact O-OG1 3.45Å; L269-V315 HydrophobicContact CD2-CG1 3.97Å; L269-A319 HydrophobicContact CD1-CB 3.94Å; L269-A319 HydrophobicContact CD2-CB 4.02Å
270	L	94.4	Very high	90.9	Very high	108 Å²	108	40.2 Å²	40.2	57%	0.565	24%	0.237	S	C	*	.	H	α-helix	trans	-63.1	-45.9	171.5	-68.2	173.9	0	0	0	111.5	V266 L267 P268 I272 T273 A274	V266-L270 HydrophobicContact CG1-CD1 4.01Å; V266-L270 HydrophobicContact CG1-CG 4.38Å; V266-L270 WeakPolarHBondContact O-CG 3.42Å; V266-L270 PolarHBondContact O-N 2.8Å; L267-L270 PolarHBondContact O-N 3.18Å; P268-L270 VanDerWaalsContact C-N 3.35Å; P268-L270 PolarHBondContact O-N 2.9Å; L270-I272 PolarHBondContact O-N 3.32Å; L270-T273 PolarHBondContact O-N 2.63Å; L270-A274 WeakPolarHBondContact O-CB 3.27Å; L270-A274 PolarHBondContact O-N 2.93Å
271	I	95.1	Very high	90.8	Very high	65 Å²	65	47.1 Å²	47.1	33%	0.333	26%	0.261	S	S	.	.	H	α-helix	trans	-60.4	-46.3	176.8	-67.5	164.1	0	0	0	110.9	T180 L184 L267 P268 A275	T180-I271 HydrophobicContact CG2-CB 4.28Å; T180-I271 HydrophobicContact CG2-CG2 3.72Å; L184-I271 HydrophobicContact CD1-CG2 4.48Å; L184-I271 HydrophobicContact CD2-CG2 4.18Å; L184-I271 HydrophobicContact CG-CG2 4.48Å; L267-I271 HydrophobicContact CD1-CD1 3.93Å; L267-I271 HydrophobicContact CD1-CG1 4.21Å; L267-I271 HydrophobicContact CG-CD1 3.99Å; L267-I271 VanDerWaalsContact O-CG1 3.31Å; L267-I271 WeakPolarHBondContact O-CG1 3.34Å; L267-I271 PolarHBondContact O-N 3.32Å; P268-I271 PolarHBondContact O-N 3.18Å; I271-A275 VanDerWaalsContact O-CB 3.22Å; I271-A275 WeakPolarHBondContact O-CB 3.47Å; I271-A275 PolarHBondContact O-N 3.25Å
272	I	93.6	Very high	90.5	Very high	1 Å²	1	50.8 Å²	50.8	1%	0.005	27%	0.274	C	S	.	.	H	α-helix	trans	-61.8	-45.9	177.4	-67.7	161.2	0	0	0	110.8	L179 T180 A183 P268 L269 L270 A275 Y276 V315	L179-I272 HydrophobicContact CB-CD1 4.06Å; T180-I272 HydrophobicContact CG2-CG1 4.43Å; T180-I272 WeakPolarHBondContact OG1-CD1 3.35Å; A183-I272 HydrophobicContact CB-CB 4.3Å; A183-I272 HydrophobicContact CB-CG1 4Å; A183-I272 HydrophobicContact CB-CG2 4.01Å; P268-I272 WeakPolarHBondContact O-CB 3.36Å; P268-I272 WeakPolarHBondContact O-CD1 3.27Å; P268-I272 WeakPolarHBondContact O-CG1 3.19Å; P268-I272 PolarHBondContact O-N 2.99Å; L269-I272 HydrophobicContact CD2-CD1 4.47Å; L270-I272 PolarHBondContact O-N 3.32Å; I272-A275 PolarHBondContact O-N 3.14Å; I272-Y276 HydrophobicContact CG2-CD2 3.55Å; I272-Y276 HydrophobicContact CG2-CE2 3.44Å; I272-Y276 VanDerWaalsContact CG2-CE2 3.44Å; I272-Y276 WeakPolarHBondContact O-CD2 3.48Å; I272-Y276 PolarHBondContact O-N 2.97Å; I272-V315 HydrophobicContact CD1-CG1 4.46Å; I272-V315 HydrophobicContact CG2-CB 4.42Å; I272-V315 HydrophobicContact CG2-CG1 3.78Å; I272-V315 HydrophobicContact CG2-CG2 3.97Å
273	T	92.1	Very high	90	Very high	81 Å²	81	48.7 Å²	48.7	50%	0.497	26%	0.264	S	S	.	.	H	α-helix	trans	-64.4	-46	-179.2	-60.3	0	0	0	0	110.9	L269 L270 A275 Y276 S277	L269-T273 VanDerWaalsContact O-CB 3.22Å; L269-T273 WeakPolarHBondContact O-CB 3.47Å; L269-T273 PolarHBondContact O-N 2.96Å; L269-T273 PolarHBondContact O-OG1 3.45Å; L270-T273 PolarHBondContact O-N 2.63Å; T273-A275 VanDerWaalsContact C-N 3.35Å; T273-A275 PolarHBondContact O-N 3.25Å; T273-Y276 PolarHBondContact O-N 3.48Å; T273-S277 WeakPolarHBondContact O-CB 3.43Å; T273-S277 PolarHBondContact O-N 3.14Å; T273-S277 PolarHBondContact O-OG 2.86Å
274	A	93.2	Very high	89.5	Confident	57 Å²	57	55.4 Å²	55.4	47%	0.471	29%	0.285	S	S	.	.	H	α-helix	trans	-63.1	-39.1	175.6	0	0	0	0	0	112.4	L270 T278	L270-A274 WeakPolarHBondContact O-CB 3.27Å; L270-A274 PolarHBondContact O-N 2.93Å; A274-T278 WeakPolarHBondContact O-CB 3.46Å; A274-T278 PolarHBondContact O-N 2.72Å; A274-T278 PolarHBondContact O-OG1 3.5Å
275	A	92.3	Very high	89	Confident	4 Å²	4	64 Å²	64	3%	0.033	32%	0.316	C	S	.	.	H	α-helix	trans	-63.4	-52.5	176.6	0	0	0	0	0	111.8	A183 R187 I271 I272 T273 T278 V279	A183-A275 HydrophobicContact CB-CB 4.39Å; R187-A275 HydrophobicContact CB-CB 4.36Å; I271-A275 VanDerWaalsContact O-CB 3.22Å; I271-A275 WeakPolarHBondContact O-CB 3.47Å; I271-A275 PolarHBondContact O-N 3.25Å; I272-A275 PolarHBondContact O-N 3.14Å; T273-A275 VanDerWaalsContact C-N 3.35Å; T273-A275 PolarHBondContact O-N 3.25Å; A275-T278 PolarHBondContact O-N 3.31Å; A275-V279 WeakPolarHBondContact O-CG2 3.22Å; A275-V279 PolarHBondContact O-N 2.96Å
276	Y	89	Confident	88	Confident	12 Å²	12	69.2 Å²	69.2	5%	0.047	34%	0.336	C	S	.	.	H	α-helix	trans	-69.6	-34.6	178.9	-70.1	-46.1	0	0	0	113	A183 R186 I272 T273 T278 V279 A280 L308 L311 L312 V315	A183-Y276 WeakPolarHBondContact CA-OH 3.3Å; A183-Y276 HydrophobicContact CB-CE1 4.23Å; A183-Y276 HydrophobicContact CB-CE2 3.86Å; R186-Y276 HydrophobicContact CB-CE1 4.36Å; I272-Y276 HydrophobicContact CG2-CD2 3.55Å; I272-Y276 HydrophobicContact CG2-CE2 3.44Å; I272-Y276 VanDerWaalsContact CG2-CE2 3.44Å; I272-Y276 WeakPolarHBondContact O-CD2 3.48Å; I272-Y276 PolarHBondContact O-N 2.97Å; T273-Y276 PolarHBondContact O-N 3.48Å; Y276-T278 VanDerWaalsContact C-N 3.28Å; Y276-T278 PolarHBondContact O-N 2.88Å; Y276-V279 PolarHBondContact O-N 2.95Å; Y276-A280 WeakPolarHBondContact O-CB 3.32Å; Y276-A280 PolarHBondContact O-N 3.29Å; Y276-L308 HydrophobicContact CD1-CD2 3.89Å; Y276-L308 HydrophobicContact CE1-CD2 3.92Å; Y276-L311 HydrophobicContact CE1-CB 4.5Å; Y276-L311 WeakPolarHBondContact OH-CB 3.03Å; Y276-L312 HydrophobicContact CD2-CD2 3.58Å; Y276-L312 HydrophobicContact CD2-CG 4.27Å; Y276-L312 HydrophobicContact CE2-CD2 4.35Å; Y276-L312 HydrophobicContact CG-CD2 3.91Å; Y276-L312 HydrophobicContact CG-CG 4.43Å; Y276-V315 HydrophobicContact CE2-CG2 4.37Å
277	S	89	Confident	86.5	Confident	54 Å²	54	71.1 Å²	71.1	38%	0.378	35%	0.345	S	S	.	.	H	α-helix	trans	-62	-37.4	173.7	-61.2	0	0	0	0	111.8	T273 R281	T273-S277 WeakPolarHBondContact O-CB 3.43Å; T273-S277 PolarHBondContact O-N 3.14Å; T273-S277 PolarHBondContact O-OG 2.86Å; S277-R281 WeakPolarHBondContact O-CB 3.17Å; S277-R281 VanDerWaalsContact O-CG 3.26Å; S277-R281 WeakPolarHBondContact O-CG 3.4Å; S277-R281 PolarHBondContact O-N 3.45Å; S277-R281 PolarHBondContact O-NE 3.46Å
278	T	89.8	Confident	84.8	Confident	44 Å²	44	71.5 Å²	71.5	27%	0.27	36%	0.359	S	S	.	.	H	α-helix	trans	-70.9	-38.5	175.4	-59.3	0	0	0	0	112	L191 A274 A275 Y276 R281 R282	L191-T278 HydrophobicContact CD1-CG2 4.06Å; A274-T278 WeakPolarHBondContact O-CB 3.46Å; A274-T278 PolarHBondContact O-N 2.72Å; A274-T278 PolarHBondContact O-OG1 3.5Å; A275-T278 PolarHBondContact O-N 3.31Å; Y276-T278 VanDerWaalsContact C-N 3.28Å; Y276-T278 PolarHBondContact O-N 2.88Å; T278-R281 PolarHBondContact OG1-NH2 2.85Å; T278-R281 VanDerWaalsContact OG1-NH2 3.16Å; T278-R282 PolarHBondContact O-N 2.69Å; T278-R282 VanDerWaalsContact O-N 3.07Å
279	V	87.1	Confident	83	Confident	1 Å²	1	78.2 Å²	78.2	1%	0.006	39%	0.393	C	S	.	.	H	α-helix	trans	-63.7	-45.2	172	170.6	0	0	0	0	111.6	R187 I190 A275 Y276 R282 L283 L308	R187-V279 HydrophobicContact CB-CG2 4.17Å; R187-V279 HydrophobicContact CG-CG2 4.24Å; I190-V279 HydrophobicContact CB-CG1 4.38Å; I190-V279 HydrophobicContact CD1-CG1 3.83Å; I190-V279 HydrophobicContact CG2-CG1 3.98Å; A275-V279 WeakPolarHBondContact O-CG2 3.22Å; A275-V279 PolarHBondContact O-N 2.96Å; Y276-V279 PolarHBondContact O-N 2.95Å; V279-R282 PolarHBondContact O-N 3.43Å; V279-L283 HydrophobicContact CG1-CD1 3.95Å; V279-L283 HydrophobicContact CG1-CG 4.5Å; V279-L283 WeakPolarHBondContact O-CG 3.4Å; V279-L283 PolarHBondContact O-N 2.92Å; V279-L308 HydrophobicContact CG1-CD1 3.52Å; V279-L308 HydrophobicContact CG1-CD2 3.91Å; V279-L308 HydrophobicContact CG1-CG 4.38Å
280	A	84.9	Confident	81.2	Confident	54 Å²	54	80.2 Å²	80.2	45%	0.446	42%	0.421	S	S	.	.	H	α-helix	trans	-61.3	-49.9	178.2	0	0	0	0	0	111.3	Y276 R282 L283 W284	Y276-A280 WeakPolarHBondContact O-CB 3.32Å; Y276-A280 PolarHBondContact O-N 3.29Å; A280-R282 VanDerWaalsContact C-N 3.31Å; A280-R282 PolarHBondContact O-N 2.87Å; A280-L283 CarbonylContact O-C 3.55Å; A280-L283 PolarHBondContact O-N 2.93Å; A280-L283 VanDerWaalsContact O-N 3.1Å; A280-W284 PolarHBondContact O-N 3.16Å
281	R	86.3	Confident	79.3	Confident	156 Å²	156	81.6 Å²	81.6	59%	0.589	43%	0.429	S	S	*	.	H	α-helix	trans	-56.3	-41.2	174.7	-73.2	-177.1	-62.8	174.1	2.7	112.4	S277 T278 W284 R285	S277-R281 WeakPolarHBondContact O-CB 3.17Å; S277-R281 VanDerWaalsContact O-CG 3.26Å; S277-R281 WeakPolarHBondContact O-CG 3.4Å; S277-R281 PolarHBondContact O-N 3.45Å; S277-R281 PolarHBondContact O-NE 3.46Å; T278-R281 PolarHBondContact OG1-NH2 2.85Å; T278-R281 VanDerWaalsContact OG1-NH2 3.16Å; R281-W284 PolarHBondContact O-N 3.33Å; R281-R285 WeakPolarHBondContact O-CG 3.26Å; R281-R285 PolarHBondContact O-N 3Å
282	R	83.8	Confident	77.2	Confident	109 Å²	109	84.3 Å²	84.3	41%	0.411	45%	0.449	S	S	.	.	H	α-helix	trans	-69.5	-33.2	176.9	-172.9	56.4	159.5	165.4	-7.6	113.1	L191 T278 V279 A280 R286	L191-R282 HydrophobicContact CD2-CB 3.71Å; L191-R282 HydrophobicContact CD2-CG 3.73Å; T278-R282 PolarHBondContact O-N 2.69Å; T278-R282 VanDerWaalsContact O-N 3.07Å; V279-R282 PolarHBondContact O-N 3.43Å; A280-R282 VanDerWaalsContact C-N 3.31Å; A280-R282 PolarHBondContact O-N 2.87Å; R282-R286 WeakPolarHBondContact O-CB 3.34Å; R282-R286 PolarHBondContact O-N 2.71Å
283	L	80	Confident	75.6	Confident	36 Å²	36	88.5 Å²	88.5	19%	0.188	47%	0.474	C	S	.	.	H	α-helix	trans	-76.5	-25.8	175	-71.7	173.9	0	0	0	113.4	I190 V279 A280 L308	I190-L283 HydrophobicContact CG2-CD2 4.41Å; V279-L283 HydrophobicContact CG1-CD1 3.95Å; V279-L283 HydrophobicContact CG1-CG 4.5Å; V279-L283 WeakPolarHBondContact O-CG 3.4Å; V279-L283 PolarHBondContact O-N 2.92Å; A280-L283 CarbonylContact O-C 3.55Å; A280-L283 PolarHBondContact O-N 2.93Å; A280-L283 VanDerWaalsContact O-N 3.1Å; L283-L308 HydrophobicContact CD1-CD1 3.34Å
284	W	79.4	Confident	74.3	Confident	202 Å²	202	89.7 Å²	89.7	77%	0.765	48%	0.482	S	S	*	.	H	α-helix	trans	-77.9	-47.4	171.8	-159.9	-44.2	0	0	0	111.2	A280 R281 R286 N287	A280-W284 PolarHBondContact O-N 3.16Å; R281-W284 PolarHBondContact O-N 3.33Å; W284-R286 PolarHBondContact O-N 3.49Å; W284-N287 WeakPolarHBondContact O-CA 3.25Å; W284-N287 WeakPolarHBondContact O-CB 3.18Å; W284-N287 PolarHBondContact O-N 3.02Å
285	R	77.1	Confident	73.1	Confident	187 Å²	187	90.3 Å²	90.3	71%	0.706	49%	0.486	S	S	*	.	H	α-helix	trans	-60.1	-34.5	176.6	-71.7	-175.1	179.1	-171.3	-0.5	112.4	R281 N287 A288	R281-R285 WeakPolarHBondContact O-CG 3.26Å; R281-R285 PolarHBondContact O-N 3Å; R285-N287 PolarHBondContact O-N 3.37Å; R285-A288 PolarHBondContact O-N 2.87Å
286	R	69.4	Low	71.8	Confident	121 Å²	121	97.6 Å²	97.6	46%	0.457	52%	0.52	S	S	.	.	T	Hydrogen-bonded Turn	trans	-76	9.6	170.1	-77.6	-179.9	162.4	157.9	-6.8	115	R282 W284	R282-R286 WeakPolarHBondContact O-CB 3.34Å; R282-R286 PolarHBondContact O-N 2.71Å; W284-R286 PolarHBondContact O-N 3.49Å
287	N	61.4	Low	71.1	Confident	91 Å²	91	103.6 Å²	103.6	49%	0.487	55%	0.547	S	S	.	.	T	Hydrogen-bonded Turn	trans	-100.3	-16.7	168.5	-170.3	75.9	0	0	0	112.5	W284 R285 R301	W284-N287 WeakPolarHBondContact O-CA 3.25Å; W284-N287 WeakPolarHBondContact O-CB 3.18Å; W284-N287 PolarHBondContact O-N 3.02Å; R285-N287 PolarHBondContact O-N 3.37Å; N287-R301 VanDerWaalsContact CG-NH2 3.32Å; N287-R301 PolarHBondContact OD1-NH1 3.43Å; N287-R301 PolarHBondContact OD1-NH2 3.22Å
288	A	56.8	Low	70.2	Confident	87 Å²	87	103.1 Å²	103.1	72%	0.719	55%	0.545	S	S	*	.	S	Bend	trans	-102.2	2.6	-173.5	0	0	0	0	0	113.6	R285	R285-A288 PolarHBondContact O-N 2.87Å
289	I	54.5	Low	69.5	Low	145 Å²	145	105.7 Å²	105.7	74%	0.744	56%	0.561	S	S	*	*	S	Bend	trans	-127.9	127.9	178.1	-55.1	174.5	0	0	0	106.3
290	G	56.7	Low	68.9	Low	70 Å²	70	110.3 Å²	110.3	72%	0.722	58%	0.583	S	S	*	*			trans	-92.6	160.6	-156.2	0	0	0	0	0	118
291	D	52.7	Low	68.4	Low	137 Å²	137	113.1 Å²	113.1	73%	0.733	58%	0.582	S	S	*	*			trans	75.5	169	137	-120.5	-40.9	0	0	0	124
292	T	51.8	Low	68	Low	122 Å²	122	115.3 Å²	115.3	75%	0.748	59%	0.59	S	S	*	*	S	Bend	trans	76.5	36.1	171.4	66.2	0	0	0	0	119.5
293	T	59.3	Low	67.6	Low	89 Å²	89	117 Å²	117	55%	0.546	60%	0.6	S	S	.	*			trans	177.4	67.2	142.4	24.4	0	0	0	0	111	A295 F297	T293-A295 PolarHBondContact O-N 2.97Å; T293-F297 WeakPolarHBondContact O-CD2 3.44Å; T293-F297 WeakPolarHBondContact OG1-CD2 3.45Å; T293-F297 WeakPolarHBondContact OG1-CE2 3.4Å
294	T	65.6	Low	67.5	Low	106 Å²	106	119.2 Å²	119.2	65%	0.65	61%	0.606	S	S	*	*	H	α-helix	trans	-51.4	-54.4	-162.1	54.7	0	0	0	0	115.5	A298	T294-A298 WeakPolarHBondContact O-CB 3.16Å; T294-A298 PolarHBondContact O-N 3.38Å
295	A	67.3	Low	67.6	Low	69 Å²	69	119 Å²	119	57%	0.57	61%	0.605	S	S	*	*	H	α-helix	trans	-64.4	-54.2	-169	0	0	0	0	0	114.2	T293 A298 V299	T293-A295 PolarHBondContact O-N 2.97Å; A295-A298 PolarHBondContact O-N 3.23Å; A295-V299 WeakPolarHBondContact O-CG2 3.48Å; A295-V299 PolarHBondContact O-N 3.46Å
296	Q	66.9	Low	67.8	Low	157 Å²	157	114.8 Å²	114.8	73%	0.734	59%	0.589	S	S	*	*	H	α-helix	trans	-67.8	-40.8	-174.7	-65.4	-171.6	4	0	0	111.9	V299 Q300	Q296-V299 PolarHBondContact O-N 3.28Å; Q296-Q300 WeakPolarHBondContact O-CB 3.45Å; Q296-Q300 PolarHBondContact O-N 2.91Å
297	F	72.3	Confident	68.3	Low	139 Å²	139	111.3 Å²	111.3	61%	0.61	58%	0.582	S	S	*	*	H	α-helix	trans	-68.6	-35.2	176.3	-79.3	-95.5	0	0	0	112.2	T293 Q300 R301	T293-F297 WeakPolarHBondContact O-CD2 3.44Å; T293-F297 WeakPolarHBondContact OG1-CD2 3.45Å; T293-F297 WeakPolarHBondContact OG1-CE2 3.4Å; F297-Q300 PolarHBondContact O-N 3.15Å; F297-R301 WeakPolarHBondContact O-CB 3.47Å; F297-R301 PolarHBondContact O-N 3.47Å
298	A	71.8	Confident	69.3	Low	43 Å²	43	107.7 Å²	107.7	36%	0.355	56%	0.562	S	S	.	*	H	α-helix	trans	-62.5	-43.7	172.3	0	0	0	0	0	112.3	T294 A295 R301 R302	T294-A298 WeakPolarHBondContact O-CB 3.16Å; T294-A298 PolarHBondContact O-N 3.38Å; A295-A298 PolarHBondContact O-N 3.23Å; A298-R301 PolarHBondContact O-N 2.89Å; A298-R302 WeakPolarHBondContact O-CB 3.43Å; A298-R302 WeakPolarHBondContact O-CG 3.3Å; A298-R302 PolarHBondContact O-N 2.88Å
299	V	75.1	Confident	70.7	Confident	99 Å²	99	105.8 Å²	105.8	60%	0.6	55%	0.546	S	S	*	.	H	α-helix	trans	-63.6	-48.1	175.8	172.4	0	0	0	0	111.2	A295 Q296 R301 R302 K303	A295-V299 WeakPolarHBondContact O-CG2 3.48Å; A295-V299 PolarHBondContact O-N 3.46Å; Q296-V299 PolarHBondContact O-N 3.28Å; V299-R301 VanDerWaalsContact C-N 3.26Å; V299-R301 PolarHBondContact O-N 2.99Å; V299-R302 PolarHBondContact O-N 3.42Å; V299-K303 WeakPolarHBondContact O-CB 3.22Å; V299-K303 PolarHBondContact O-N 2.96Å
300	Q	73.6	Confident	72.2	Confident	97 Å²	97	99.4 Å²	99.4	45%	0.453	51%	0.513	S	S	.	.	H	α-helix	trans	-56.7	-40.2	175.5	-173.3	78	-77.8	0	0	111.6	Q296 F297 R304	Q296-Q300 WeakPolarHBondContact O-CB 3.45Å; Q296-Q300 PolarHBondContact O-N 2.91Å; F297-Q300 PolarHBondContact O-N 3.15Å; Q300-R304 WeakPolarHBondContact O-CG 3.38Å; Q300-R304 PolarHBondContact O-N 3Å; Q300-R304 VanDerWaalsContact O-N 3.09Å
301	R	74.5	Confident	73.6	Confident	114 Å²	114	96.3 Å²	96.3	43%	0.43	48%	0.48	S	S	.	.	H	α-helix	trans	-72	-44	178.4	-176.6	177.4	174	-144.2	-5.2	112.9	N287 F297 A298 V299 K303 R304 R305	N287-R301 VanDerWaalsContact CG-NH2 3.32Å; N287-R301 PolarHBondContact OD1-NH1 3.43Å; N287-R301 PolarHBondContact OD1-NH2 3.22Å; F297-R301 WeakPolarHBondContact O-CB 3.47Å; F297-R301 PolarHBondContact O-N 3.47Å; A298-R301 PolarHBondContact O-N 2.89Å; V299-R301 VanDerWaalsContact C-N 3.26Å; V299-R301 PolarHBondContact O-N 2.99Å; R301-K303 VanDerWaalsContact C-N 3.3Å; R301-K303 PolarHBondContact O-N 3.38Å; R301-R304 PolarHBondContact O-N 3.26Å; R301-R305 PolarHBondContact O-N 3.39Å
302	R	78.1	Confident	75.3	Confident	201 Å²	201	94.1 Å²	94.1	76%	0.758	47%	0.468	S	S	*	.	H	α-helix	trans	-56.9	-44.7	173.4	-76	177.6	-179.8	-170.2	0.8	110.5	A298 V299 R305 R306	A298-R302 WeakPolarHBondContact O-CB 3.43Å; A298-R302 WeakPolarHBondContact O-CG 3.3Å; A298-R302 PolarHBondContact O-N 2.88Å; V299-R302 PolarHBondContact O-N 3.42Å; R302-R305 PolarHBondContact O-N 3.27Å; R302-R306 PolarHBondContact O-N 3.32Å
303	K	75.9	Confident	77.1	Confident	145 Å²	145	90 Å²	90	63%	0.63	45%	0.447	S	S	*	.	H	α-helix	trans	-58.4	-49	174.7	-170.2	174.8	-177.4	176.7	0	112	V299 R301 R306 T307	V299-K303 WeakPolarHBondContact O-CB 3.22Å; V299-K303 PolarHBondContact O-N 2.96Å; R301-K303 VanDerWaalsContact C-N 3.3Å; R301-K303 PolarHBondContact O-N 3.38Å; K303-R306 PolarHBondContact O-N 3.08Å; K303-T307 PolarHBondContact O-N 3.07Å; K303-T307 PolarHBondContact O-OG1 3.44Å
304	R	77.6	Confident	78.6	Confident	82 Å²	82	85.9 Å²	85.9	31%	0.309	42%	0.421	S	S	.	.	H	α-helix	trans	-61	-43.9	176.6	-71.8	177.1	-171.9	-163.5	3.7	112.9	Q300 R301 R306 T307 L308	Q300-R304 WeakPolarHBondContact O-CG 3.38Å; Q300-R304 PolarHBondContact O-N 3Å; Q300-R304 VanDerWaalsContact O-N 3.09Å; R301-R304 PolarHBondContact O-N 3.26Å; R304-R306 PolarHBondContact O-N 3.39Å; R304-T307 PolarHBondContact O-N 3.33Å; R304-L308 WeakPolarHBondContact O-CG 3.45Å; R304-L308 PolarHBondContact O-N 2.03Å
305	R	80.9	Confident	79.8	Confident	199 Å²	199	81.4 Å²	81.4	75%	0.751	39%	0.394	S	S	*	.	H	α-helix	trans	-62	-41.7	177.2	-169.7	178.9	-178.7	-174.3	0.4	111.4	R301 R302 L308 A309	R301-R305 PolarHBondContact O-N 3.39Å; R302-R305 PolarHBondContact O-N 3.27Å; R305-L308 PolarHBondContact O-N 3.31Å; R305-A309 WeakPolarHBondContact O-CB 3.46Å; R305-A309 PolarHBondContact O-N 3.43Å
306	R	81.5	Confident	81	Confident	98 Å²	98	79.8 Å²	79.8	37%	0.37	38%	0.384	S	S	.	.	H	α-helix	trans	-63	-43.8	175.4	-170.9	176.7	-177.6	134.7	4.2	112.4	R302 K303 R304 L308 A309 M310 C364 L365	R302-R306 PolarHBondContact O-N 3.32Å; K303-R306 PolarHBondContact O-N 3.08Å; R304-R306 PolarHBondContact O-N 3.39Å; R306-L308 VanDerWaalsContact C-N 3.33Å; R306-L308 PolarHBondContact O-N 3.12Å; R306-A309 PolarHBondContact O-N 2.83Å; R306-M310 WeakPolarHBondContact O-CB 3.48Å; R306-M310 PolarHBondContact O-N 2.89Å; R306-C364 PolarHBondContact NH2-O 2.97Å; R306-L365 WeakPolarHBondContact CD-O 3.46Å; R306-L365 WeakPolarHBondContact CG-O 3.12Å; R306-L365 PolarHBondContact NE-O 2.95Å
307	T	80.4	Confident	82.2	Confident	48 Å²	48	74.4 Å²	74.4	29%	0.294	36%	0.362	S	S	.	.	H	α-helix	trans	-64.2	-35.8	175.8	-56.6	0	0	0	0	112.5	K303 R304 L311	K303-T307 PolarHBondContact O-N 3.07Å; K303-T307 PolarHBondContact O-OG1 3.44Å; R304-T307 PolarHBondContact O-N 3.33Å; T307-L311 HydrophobicContact CG2-CD1 4.38Å; T307-L311 WeakPolarHBondContact O-CG 3.49Å; T307-L311 PolarHBondContact O-N 2.84Å
308	L	82.5	Confident	83.1	Confident	15 Å²	15	68.3 Å²	68.3	8%	0.079	34%	0.335	C	S	.	.	H	α-helix	trans	-71.9	-42.4	175.1	-71.9	167.4	0	0	0	112.4	I190 Y276 V279 L283 R304 R305 R306 M310 L311 L312	I190-L308 HydrophobicContact CD1-CD1 4.06Å; I190-L308 HydrophobicContact CD1-CD2 3.93Å; I190-L308 HydrophobicContact CD1-CG 4.21Å; Y276-L308 HydrophobicContact CD1-CD2 3.89Å; Y276-L308 HydrophobicContact CE1-CD2 3.92Å; V279-L308 HydrophobicContact CG1-CD1 3.52Å; V279-L308 HydrophobicContact CG1-CD2 3.91Å; V279-L308 HydrophobicContact CG1-CG 4.38Å; L283-L308 HydrophobicContact CD1-CD1 3.34Å; R304-L308 WeakPolarHBondContact O-CG 3.45Å; R304-L308 PolarHBondContact O-N 2.03Å; R305-L308 PolarHBondContact O-N 3.31Å; R306-L308 VanDerWaalsContact C-N 3.33Å; R306-L308 PolarHBondContact O-N 3.12Å; L308-M310 VanDerWaalsContact C-N 3.27Å; L308-M310 PolarHBondContact O-N 2.9Å; L308-L311 PolarHBondContact O-N 2.8Å; L308-L311 VanDerWaalsContact O-N 3.15Å; L308-L312 WeakPolarHBondContact O-CB 3.33Å; L308-L312 WeakPolarHBondContact O-CG 3.3Å; L308-L312 PolarHBondContact O-N 2.94Å
309	A	85.4	Confident	84.1	Confident	46 Å²	46	67.1 Å²	67.1	38%	0.38	33%	0.325	S	S	.	.	H	α-helix	trans	-59.3	-39.2	174.4	0	0	0	0	0	111.8	R305 R306 A313	R305-A309 WeakPolarHBondContact O-CB 3.46Å; R305-A309 PolarHBondContact O-N 3.43Å; R306-A309 PolarHBondContact O-N 2.83Å; A309-A313 WeakPolarHBondContact O-CB 3.22Å; A309-A313 PolarHBondContact O-N 2.94Å
310	M	85.9	Confident	85	Confident	12 Å²	12	67.3 Å²	67.3	6%	0.059	33%	0.326	C	S	.	.	H	α-helix	trans	-58.4	-46.8	172.6	-175.3	-173.3	83.4	0	0	112.7	R306 L308 A313 V314 I361 Y362 L365 N366	R306-M310 WeakPolarHBondContact O-CB 3.48Å; R306-M310 PolarHBondContact O-N 2.89Å; L308-M310 VanDerWaalsContact C-N 3.27Å; L308-M310 PolarHBondContact O-N 2.9Å; M310-A313 PolarHBondContact O-N 3.47Å; M310-V314 WeakPolarHBondContact O-CG2 3.44Å; M310-V314 PolarHBondContact O-N 3.45Å; M310-I361 HydrophobicContact CG-CG2 3.96Å; M310-Y362 HydrophobicContact CE-CD1 4.22Å; M310-Y362 HydrophobicContact CE-CE1 4.35Å; M310-Y362 HydrophobicContact CG-CD1 4.34Å; M310-Y362 HydrophobicContact SD-CD1 3.96Å; M310-L365 HydrophobicContact CB-CB 3.73Å; M310-L365 HydrophobicContact CB-CD1 3.98Å; M310-L365 HydrophobicContact CG-CB 3.8Å; M310-L365 HydrophobicContact CG-CD1 4.37Å; M310-L365 HydrophobicContact SD-CB 4.33Å; M310-N366 HydrophobicContact SD-CB 3.94Å
311	L	85.8	Confident	86	Confident	5 Å²	5	63 Å²	63	3%	0.026	31%	0.306	C	S	.	.	H	α-helix	trans	-74.6	-34.4	-177	-66.3	172.1	0	0	0	112.6	I182 R186 Y276 T307 L308 A313 V314 V315	I182-L311 HydrophobicContact CG2-CD1 3.92Å; I182-L311 HydrophobicContact CG2-CD2 3.68Å; I182-L311 HydrophobicContact CG2-CG 4.41Å; R186-L311 HydrophobicContact CG-CD1 3.63Å; Y276-L311 HydrophobicContact CE1-CB 4.5Å; Y276-L311 WeakPolarHBondContact OH-CB 3.03Å; T307-L311 HydrophobicContact CG2-CD1 4.38Å; T307-L311 WeakPolarHBondContact O-CG 3.49Å; T307-L311 PolarHBondContact O-N 2.84Å; L308-L311 PolarHBondContact O-N 2.8Å; L308-L311 VanDerWaalsContact O-N 3.15Å; L311-A313 VanDerWaalsContact C-N 3.34Å; L311-V314 PolarHBondContact O-N 3.39Å; L311-V315 VanDerWaalsContact O-CG2 3.32Å; L311-V315 WeakPolarHBondContact O-CG2 3.27Å; L311-V315 PolarHBondContact O-N 2.92Å
312	L	88.3	Confident	86.9	Confident	91 Å²	91	57.9 Å²	57.9	48%	0.476	29%	0.287	S	S	.	.	H	α-helix	trans	-64.3	-38.6	169.9	-74.2	167.4	0	0	0	111.6	Y276 L308 V315 G316	Y276-L312 HydrophobicContact CD2-CD2 3.58Å; Y276-L312 HydrophobicContact CD2-CG 4.27Å; Y276-L312 HydrophobicContact CE2-CD2 4.35Å; Y276-L312 HydrophobicContact CG-CD2 3.91Å; Y276-L312 HydrophobicContact CG-CG 4.43Å; L308-L312 WeakPolarHBondContact O-CB 3.33Å; L308-L312 WeakPolarHBondContact O-CG 3.3Å; L308-L312 PolarHBondContact O-N 2.94Å; L312-V315 PolarHBondContact O-N 2.88Å; L312-G316 PolarHBondContact O-N 3.45Å
313	A	90.3	Very high	87.6	Confident	36 Å²	36	53.5 Å²	53.5	30%	0.298	27%	0.274	S	S	.	.	H	α-helix	trans	-64.2	-45.8	174.9	0	0	0	0	0	112	A309 M310 L311 V315 G316 V317 I361	A309-A313 WeakPolarHBondContact O-CB 3.22Å; A309-A313 PolarHBondContact O-N 2.94Å; M310-A313 PolarHBondContact O-N 3.47Å; L311-A313 VanDerWaalsContact C-N 3.34Å; A313-V315 PolarHBondContact O-N 3.44Å; A313-G316 PolarHBondContact O-N 2.71Å; A313-V317 WeakPolarHBondContact O-CB 3.32Å; A313-V317 VanDerWaalsContact O-CG2 3.27Å; A313-V317 WeakPolarHBondContact O-CG2 3.31Å; A313-V317 PolarHBondContact O-N 3.45Å; A313-I361 HydrophobicContact CB-CG2 4.01Å
314	V	90.2	Very high	88.4	Confident	2 Å²	2	48 Å²	48	1%	0.012	25%	0.253	C	S	.	.	H	α-helix	trans	-57.9	-49.5	174.9	172.9	0	0	0	0	111.2	L179 M310 L311 F318 N358 I361 Y362	L179-V314 HydrophobicContact CD1-CG1 4.49Å; L179-V314 HydrophobicContact CD2-CG1 3.49Å; L179-V314 VanDerWaalsContact CD2-CG1 3.49Å; M310-V314 WeakPolarHBondContact O-CG2 3.44Å; M310-V314 PolarHBondContact O-N 3.45Å; L311-V314 PolarHBondContact O-N 3.39Å; V314-F318 WeakPolarHBondContact O-CB 3.42Å; V314-F318 PolarHBondContact O-N 2.9Å; V314-N358 WeakPolarHBondContact CG1-OD1 3.48Å; V314-I361 HydrophobicContact CG2-CB 4.17Å; V314-I361 HydrophobicContact CG2-CD1 4.06Å; V314-I361 HydrophobicContact CG2-CG2 3.68Å; V314-Y362 HydrophobicContact CG2-CE1 3.91Å
315	V	90.9	Very high	89	Confident	12 Å²	12	44.4 Å²	44.4	7%	0.073	24%	0.24	C	C	.	.	H	α-helix	trans	-66.1	-43	-178.4	170.3	0	0	0	0	112	L179 L269 I272 Y276 L311 L312 A313 F318 A319	L179-V315 HydrophobicContact CB-CG2 4.26Å; L179-V315 HydrophobicContact CD1-CG2 4.35Å; L179-V315 HydrophobicContact CD2-CG2 4.23Å; L269-V315 HydrophobicContact CD2-CG1 3.97Å; I272-V315 HydrophobicContact CD1-CG1 4.46Å; I272-V315 HydrophobicContact CG2-CB 4.42Å; I272-V315 HydrophobicContact CG2-CG1 3.78Å; I272-V315 HydrophobicContact CG2-CG2 3.97Å; Y276-V315 HydrophobicContact CE2-CG2 4.37Å; L311-V315 VanDerWaalsContact O-CG2 3.32Å; L311-V315 WeakPolarHBondContact O-CG2 3.27Å; L311-V315 PolarHBondContact O-N 2.92Å; L312-V315 PolarHBondContact O-N 2.88Å; A313-V315 PolarHBondContact O-N 3.44Å; V315-F318 PolarHBondContact O-N 2.96Å; V315-A319 WeakPolarHBondContact O-CB 3.14Å; V315-A319 PolarHBondContact O-N 3.21Å
316	G	92.6	Very high	89.4	Confident	35 Å²	35	35.8 Å²	35.8	36%	0.361	21%	0.209	S	C	.	.	H	α-helix	trans	-64.2	-43.3	179.1	0	0	0	0	0	112.1	L312 A313 A319 V320	L312-G316 PolarHBondContact O-N 3.45Å; A313-G316 PolarHBondContact O-N 2.71Å; G316-A319 PolarHBondContact O-N 2.91Å; G316-V320 WeakPolarHBondContact O-CB 3.47Å; G316-V320 VanDerWaalsContact O-CG2 3.31Å; G316-V320 WeakPolarHBondContact O-CG2 3.31Å; G316-V320 PolarHBondContact O-N 2.9Å
317	V	93	Very high	89.8	Confident	44 Å²	44	32.5 Å²	32.5	27%	0.267	20%	0.2	S	C	.	.	H	α-helix	trans	-63.2	-46	174.4	168.1	0	0	0	0	111	A313 A319 V320 C321 Y357 I361	A313-V317 WeakPolarHBondContact O-CB 3.32Å; A313-V317 VanDerWaalsContact O-CG2 3.27Å; A313-V317 WeakPolarHBondContact O-CG2 3.31Å; A313-V317 PolarHBondContact O-N 3.45Å; V317-A319 PolarHBondContact O-N 2.99Å; V317-V320 PolarHBondContact O-N 2.93Å; V317-C321 VanDerWaalsContact O-CB 3.3Å; V317-C321 WeakPolarHBondContact O-CB 3.31Å; V317-C321 PolarHBondContact O-N 2.91Å; V317-C321 PolarHBondContact O-SG 3.45Å; V317-Y357 HydrophobicContact CG1-CD2 3.3Å; V317-Y357 HydrophobicContact CG1-CE2 4.1Å; V317-Y357 HydrophobicContact CG1-CG 3.86Å; V317-I361 HydrophobicContact CB-CD1 4.39Å; V317-I361 HydrophobicContact CG2-CD1 4.19Å
318	F	91.1	Very high	90.1	Very high	10 Å²	10	30.8 Å²	30.8	4%	0.044	19%	0.189	C	C	.	.	H	α-helix	trans	-57.8	-48.4	176.5	-178.9	-94.3	0	0	0	111.9	L172 T176 L179 V314 V315 C321 W322	L172-F318 HydrophobicContact CD1-CE1 4.5Å; L172-F318 HydrophobicContact CD1-CE2 4.45Å; L172-F318 HydrophobicContact CD1-CZ 3.77Å; T176-F318 HydrophobicContact CG2-CE1 4.04Å; T176-F318 WeakPolarHBondContact OG1-CE1 3.5Å; T176-F318 VanDerWaalsContact OG1-CZ 3.28Å; T176-F318 WeakPolarHBondContact OG1-CZ 3.38Å; L179-F318 HydrophobicContact CD1-CB 3.98Å; L179-F318 HydrophobicContact CD1-CD1 3.91Å; L179-F318 HydrophobicContact CD1-CD2 4.14Å; L179-F318 HydrophobicContact CD1-CE1 4.39Å; L179-F318 HydrophobicContact CD1-CG 3.75Å; V314-F318 WeakPolarHBondContact O-CB 3.42Å; V314-F318 PolarHBondContact O-N 2.9Å; V315-F318 PolarHBondContact O-N 2.96Å; F318-C321 PolarHBondContact O-N 3.31Å; F318-W322 AromaticContact CD2-CD1 3.78Å; F318-W322 AromaticContact CD2-NE1 3.98Å; F318-W322 AromaticContact CE2-CD1 3.79Å; F318-W322 AromaticContact CE2-NE1 3.81Å; F318-W322 WeakPolarHBondContact O-CB 3.49Å; F318-W322 VanDerWaalsContact O-CD1 3.32Å; F318-W322 PolarHBondContact O-N 3.5Å
319	A	92.4	Very high	90.2	Very high	19 Å²	19	31 Å²	31	16%	0.157	19%	0.191	C	C	.	.	H	α-helix	trans	-61.3	-51.2	177.6	0	0	0	0	0	112.2	Y265 L269 V315 G316 V317 C321 W322 F323	Y265-A319 VanDerWaalsContact OH-CA 3.32Å; Y265-A319 WeakPolarHBondContact OH-CA 3.24Å; Y265-A319 PolarHBondContact OH-O 3.21Å; L269-A319 HydrophobicContact CD1-CB 3.94Å; L269-A319 HydrophobicContact CD2-CB 4.02Å; V315-A319 WeakPolarHBondContact O-CB 3.14Å; V315-A319 PolarHBondContact O-N 3.21Å; G316-A319 PolarHBondContact O-N 2.91Å; V317-A319 PolarHBondContact O-N 2.99Å; A319-C321 VanDerWaalsContact C-N 3.28Å; A319-C321 PolarHBondContact O-N 2.99Å; A319-W322 PolarHBondContact O-N 3.3Å; A319-F323 VanDerWaalsContact O-CB 3.22Å; A319-F323 WeakPolarHBondContact O-CB 3.34Å; A319-F323 PolarHBondContact O-N 2.95Å
320	V	94.7	Very high	90.2	Very high	102 Å²	102	30 Å²	30	62%	0.618	18%	0.179	S	C	*	.	H	α-helix	trans	-62.2	-35.5	-179.2	171.3	0	0	0	0	112.1	G316 V317 P324	G316-V320 WeakPolarHBondContact O-CB 3.47Å; G316-V320 VanDerWaalsContact O-CG2 3.31Å; G316-V320 WeakPolarHBondContact O-CG2 3.31Å; G316-V320 PolarHBondContact O-N 2.9Å; V317-V320 PolarHBondContact O-N 2.93Å; V320-P324 WeakPolarHBondContact O-CD 3.34Å
321	C	94.8	Very high	90.1	Very high	6 Å²	6	32.8 Å²	32.8	4%	0.041	19%	0.194	C	C	.	.	H	α-helix	trans	-71.9	-41.6	178.8	-67.6	0	0	0	0	113	V317 F318 A319 L350 A351	V317-C321 VanDerWaalsContact O-CB 3.3Å; V317-C321 WeakPolarHBondContact O-CB 3.31Å; V317-C321 PolarHBondContact O-N 2.91Å; V317-C321 PolarHBondContact O-SG 3.45Å; F318-C321 PolarHBondContact O-N 3.31Å; A319-C321 VanDerWaalsContact C-N 3.28Å; A319-C321 PolarHBondContact O-N 2.99Å; C321-L350 WeakPolarHBondContact CB-O 3.07Å; C321-A351 WeakPolarHBondContact O-CA 3.4Å; C321-A351 PolarHBondContact O-N 3.5Å
322	W	92.9	Very high	89.8	Confident	7 Å²	7	34.8 Å²	34.8	3%	0.027	21%	0.205	C	C	.	.	H	α-helix	trans	-91.5	-22.5	-173.4	-75.8	91.2	0	0	0	114.3	I137 L172 Y265 F318 A319 L325 N326 A351 M352 S354	I137-W322 HydrophobicContact CD1-CH2 3.91Å; I137-W322 HydrophobicContact CD1-CZ2 4.28Å; L172-W322 HydrophobicContact CB-CH2 4.15Å; L172-W322 HydrophobicContact CB-CZ3 4.19Å; L172-W322 HydrophobicContact CD1-CD2 3.67Å; L172-W322 HydrophobicContact CD1-CE3 3.67Å; L172-W322 HydrophobicContact CD1-CG 4.07Å; L172-W322 HydrophobicContact CD1-CH2 4.44Å; L172-W322 HydrophobicContact CD1-CZ2 4.47Å; L172-W322 HydrophobicContact CD1-CZ3 4.06Å; L172-W322 HydrophobicContact CD2-CE3 4.11Å; L172-W322 HydrophobicContact CD2-CZ3 4.06Å; L172-W322 HydrophobicContact CG-CE3 4.36Å; L172-W322 HydrophobicContact CG-CZ3 4.33Å; Y265-W322 HydrophobicContact CE2-CB 4Å; F318-W322 AromaticContact CD2-CD1 3.78Å; F318-W322 AromaticContact CD2-NE1 3.98Å; F318-W322 AromaticContact CE2-CD1 3.79Å; F318-W322 AromaticContact CE2-NE1 3.81Å; F318-W322 WeakPolarHBondContact O-CB 3.49Å; F318-W322 VanDerWaalsContact O-CD1 3.32Å; F318-W322 PolarHBondContact O-N 3.5Å; A319-W322 PolarHBondContact O-N 3.3Å; W322-L325 HydrophobicContact CE3-CD2 4.16Å; W322-L325 HydrophobicContact CZ3-CD2 4Å; W322-L325 PolarHBondContact O-N 3.48Å; W322-N326 PolarHBondContact O-N 2.96Å; W322-N326 VanDerWaalsContact O-N 3.12Å; W322-N326 PolarHBondContact O-ND2 3.39Å; W322-A351 HydrophobicContact CD2-CB 3.82Å; W322-A351 HydrophobicContact CE3-CB 3.73Å; W322-A351 HydrophobicContact CG-CB 4.39Å; W322-A351 HydrophobicContact CH2-CB 4.41Å; W322-A351 HydrophobicContact CZ2-CB 4.44Å; W322-A351 HydrophobicContact CZ3-CB 4.06Å; W322-A351 PolarHBondContact NE1-O 3.39Å; W322-M352 HydrophobicContact CH2-CE 3.91Å; W322-S354 PolarHBondContact NE1-OG 3.33Å
323	F	92.4	Very high	89.3	Confident	110 Å²	110	30.5 Å²	30.5	48%	0.482	18%	0.182	S	C	.	.	H	α-helix	trans	-51.8	-51.1	179.6	178.7	-103.7	0	0	0	113.5	Y265 A319 L325 N326 C327	Y265-F323 HydrophobicContact CE1-CD2 4.14Å; Y265-F323 WeakPolarHBondContact OH-CB 3.34Å; A319-F323 VanDerWaalsContact O-CB 3.22Å; A319-F323 WeakPolarHBondContact O-CB 3.34Å; A319-F323 PolarHBondContact O-N 2.95Å; F323-L325 VanDerWaalsContact C-N 3.35Å; F323-L325 PolarHBondContact O-N 3.49Å; F323-N326 PolarHBondContact O-N 3.01Å; F323-C327 WeakPolarHBondContact CE2-SG 3.33Å; F323-C327 VanDerWaalsContact CZ-SG 3.57Å; F323-C327 PolarHBondContact O-N 2.9Å; F323-C327 PolarHBondContact O-SG 3.46Å
324	P	92.8	Very high	88.6	Confident	29 Å²	29	30.7 Å²	30.7	19%	0.188	18%	0.181	C	C	.	.	H	α-helix	trans	-66.4	-36.1	-173.7	-22.2	36.7	0	0	0	112.8	V320 Y328 F347 L350	V320-P324 WeakPolarHBondContact O-CD 3.34Å; P324-Y328 WeakPolarHBondContact O-CB 3.23Å; P324-Y328 PolarHBondContact O-N 2.89Å; P324-F347 HydrophobicContact CB-CB 4.18Å; P324-F347 HydrophobicContact CB-CD1 3.42Å; P324-F347 VanDerWaalsContact CB-CD1 3.42Å; P324-F347 HydrophobicContact CB-CD2 4.41Å; P324-F347 HydrophobicContact CB-CE1 3.83Å; P324-F347 HydrophobicContact CB-CG 3.76Å; P324-F347 HydrophobicContact CB-CZ 4.47Å; P324-L350 HydrophobicContact CG-CD2 4.08Å
325	L	89.9	Confident	87.8	Confident	7 Å²	7	36.8 Å²	36.8	4%	0.037	21%	0.21	C	C	.	.	H	α-helix	trans	-68.2	-44.4	177.2	-178.9	64.7	0	0	0	111.5	W322 F323 Y328 V329 Y344 F347 H348 A351	W322-L325 HydrophobicContact CE3-CD2 4.16Å; W322-L325 HydrophobicContact CZ3-CD2 4Å; W322-L325 PolarHBondContact O-N 3.48Å; F323-L325 VanDerWaalsContact C-N 3.35Å; F323-L325 PolarHBondContact O-N 3.49Å; L325-Y328 PolarHBondContact O-N 3.49Å; L325-V329 HydrophobicContact CD1-CG2 4.43Å; L325-V329 WeakPolarHBondContact O-CG2 3.45Å; L325-V329 PolarHBondContact O-N 3.32Å; L325-Y344 HydrophobicContact CD1-CD2 4.24Å; L325-Y344 HydrophobicContact CD1-CE2 3.82Å; L325-F347 HydrophobicContact CB-CB 4.23Å; L325-F347 HydrophobicContact CD1-CB 4.43Å; L325-H348 HydrophobicContact CD1-CB 4.25Å; L325-A351 HydrophobicContact CB-CB 4.09Å; L325-A351 HydrophobicContact CD2-CB 3.62Å
326	N	90.4	Very high	86.8	Confident	17 Å²	17	39.3 Å²	39.3	9%	0.091	23%	0.232	C	C	.	.	H	α-helix	trans	-64.7	-47.1	179.6	-79.7	-94.3	0	0	0	111.2	F261 W322 F323 Y328 V329 V330	F261-N326 HydrophobicContact CD2-CB 3.66Å; F261-N326 HydrophobicContact CE2-CB 3.72Å; W322-N326 PolarHBondContact O-N 2.96Å; W322-N326 VanDerWaalsContact O-N 3.12Å; W322-N326 PolarHBondContact O-ND2 3.39Å; F323-N326 PolarHBondContact O-N 3.01Å; N326-Y328 PolarHBondContact O-N 3.01Å; N326-V329 PolarHBondContact O-N 3.36Å; N326-V330 WeakPolarHBondContact O-CG2 3.08Å; N326-V330 PolarHBondContact O-N 3.43Å
327	C	88.9	Confident	86	Confident	29 Å²	29	41.3 Å²	41.3	20%	0.196	23%	0.233	C	C	.	.	H	α-helix	trans	-62.3	-40.8	176.3	-68.8	0	0	0	0	112.3	F323 V329 V330 L331	F323-C327 WeakPolarHBondContact CE2-SG 3.33Å; F323-C327 VanDerWaalsContact CZ-SG 3.57Å; F323-C327 PolarHBondContact O-N 2.9Å; F323-C327 PolarHBondContact O-SG 3.46Å; C327-V329 PolarHBondContact O-N 3.41Å; C327-V330 PolarHBondContact O-N 2.77Å; C327-L331 WeakPolarHBondContact O-CB 3.34Å; C327-L331 WeakPolarHBondContact O-CD1 3.34Å; C327-L331 VanDerWaalsContact O-CG 3.23Å; C327-L331 WeakPolarHBondContact O-CG 3.39Å; C327-L331 PolarHBondContact O-N 3.15Å
328	Y	86.4	Confident	85	Confident	13 Å²	13	47.8 Å²	47.8	5%	0.051	26%	0.261	C	S	.	.	H	α-helix	trans	-63.5	-39.7	176.2	-179	-88.1	0	0	0	112.5	P324 L325 N326 L332 S340 L343 Y344 F347	P324-Y328 WeakPolarHBondContact O-CB 3.23Å; P324-Y328 PolarHBondContact O-N 2.89Å; L325-Y328 PolarHBondContact O-N 3.49Å; N326-Y328 PolarHBondContact O-N 3.01Å; Y328-L332 HydrophobicContact CE1-CD2 4.28Å; Y328-L332 VanDerWaalsContact O-CB 3.27Å; Y328-L332 WeakPolarHBondContact O-CB 3.49Å; Y328-L332 PolarHBondContact O-N 3.16Å; Y328-S340 PolarHBondContact OH-N 3Å; Y328-S340 PolarHBondContact OH-O 3.42Å; Y328-L343 HydrophobicContact CE2-CB 4.16Å; Y328-Y344 AromaticContact CD1-CD2 3.91Å; Y328-Y344 HydrophobicContact CD1-CD2 3.91Å; Y328-Y344 AromaticContact CE1-CD2 3.72Å; Y328-Y344 HydrophobicContact CE1-CD2 3.72Å; Y328-Y344 HydrophobicContact CE1-CG 4.32Å; Y328-F347 AromaticContact CD2-CD2 3.94Å; Y328-F347 HydrophobicContact CD2-CD2 3.94Å; Y328-F347 AromaticContact CD2-CE2 3.81Å; Y328-F347 HydrophobicContact CD2-CE2 3.81Å; Y328-F347 AromaticContact CG-CD2 3.88Å; Y328-F347 HydrophobicContact CG-CD2 3.88Å; Y328-F347 HydrophobicContact CG-CE2 4.18Å
329	V	84.6	Confident	84	Confident	20 Å²	20	50.2 Å²	50.2	12%	0.121	28%	0.279	C	S	.	.	H	α-helix	trans	-64.5	-46.1	176.2	167.9	0	0	0	0	111.1	D257 L325 N326 C327 L332 S333	D257-V329 HydrophobicContact CB-CG1 4.2Å; D257-V329 WeakPolarHBondContact OD1-CG1 3.35Å; D257-V329 WeakPolarHBondContact OD2-CG1 3.4Å; L325-V329 HydrophobicContact CD1-CG2 4.43Å; L325-V329 WeakPolarHBondContact O-CG2 3.45Å; L325-V329 PolarHBondContact O-N 3.32Å; N326-V329 PolarHBondContact O-N 3.36Å; C327-V329 PolarHBondContact O-N 3.41Å; V329-L332 PolarHBondContact O-N 2.91Å; V329-S333 PolarHBondContact O-N 3.13Å
330	V	85.8	Confident	83.2	Confident	23 Å²	23	51.3 Å²	51.3	14%	0.139	29%	0.286	C	S	.	.	H	α-helix	trans	-62	-47	177	174.1	0	0	0	0	111.3	L258 F261 N326 C327 L332 S333 S334	L258-V330 HydrophobicContact CD1-CG1 4.16Å; F261-V330 HydrophobicContact CB-CG2 3.91Å; F261-V330 HydrophobicContact CD1-CG2 4.21Å; F261-V330 HydrophobicContact CG-CG2 4.08Å; N326-V330 WeakPolarHBondContact O-CG2 3.08Å; N326-V330 PolarHBondContact O-N 3.43Å; C327-V330 PolarHBondContact O-N 2.77Å; V330-L332 VanDerWaalsContact C-N 3.28Å; V330-L332 PolarHBondContact O-N 2.83Å; V330-S333 PolarHBondContact O-N 3.15Å; V330-S333 VanDerWaalsContact O-N 3.15Å; V330-S333 PolarHBondContact O-OG 2.88Å; V330-S334 PolarHBondContact O-N 3.05Å
331	L	83.7	Confident	82.3	Confident	71 Å²	71	52.5 Å²	52.5	37%	0.372	29%	0.289	S	S	.	.	H	α-helix	trans	-65.7	-27.9	179.3	-71.1	164.7	0	0	0	113.5	C327 S334 A336 I337	C327-L331 WeakPolarHBondContact O-CB 3.34Å; C327-L331 WeakPolarHBondContact O-CD1 3.34Å; C327-L331 VanDerWaalsContact O-CG 3.23Å; C327-L331 WeakPolarHBondContact O-CG 3.39Å; C327-L331 PolarHBondContact O-N 3.15Å; L331-S334 PolarHBondContact O-OG 3.01Å; L331-A336 HydrophobicContact CD2-CB 4.25Å; L331-A336 PolarHBondContact O-N 3.18Å; L331-I337 HydrophobicContact CB-CD1 4.03Å; L331-I337 HydrophobicContact CB-CG1 4.32Å; L331-I337 HydrophobicContact CD1-CD1 3.89Å; L331-I337 HydrophobicContact CG-CD1 4.42Å
332	L	79.7	Confident	81.4	Confident	47 Å²	47	55.2 Å²	55.2	25%	0.246	31%	0.312	C	S	.	.	H	α-helix	trans	-74.2	-42.1	171.8	-171.3	71.7	0	0	0	111.1	W253 Y328 V329 V330 S334 Q335	W253-L332 HydrophobicContact CH2-CD2 4.15Å; W253-L332 HydrophobicContact CH2-CG 3.98Å; W253-L332 HydrophobicContact CZ2-CD2 4.4Å; W253-L332 HydrophobicContact CZ2-CG 4.48Å; Y328-L332 HydrophobicContact CE1-CD2 4.28Å; Y328-L332 VanDerWaalsContact O-CB 3.27Å; Y328-L332 WeakPolarHBondContact O-CB 3.49Å; Y328-L332 PolarHBondContact O-N 3.16Å; V329-L332 PolarHBondContact O-N 2.91Å; V330-L332 VanDerWaalsContact C-N 3.28Å; V330-L332 PolarHBondContact O-N 2.83Å; L332-S334 VanDerWaalsContact C-N 3.29Å; L332-S334 PolarHBondContact O-N 2.81Å; L332-Q335 PolarHBondContact O-N 2.8Å; L332-Q335 VanDerWaalsContact O-N 3.14Å
333	S	77.3	Confident	80.9	Confident	1 Å²	1	58.8 Å²	58.8	1%	0.007	33%	0.331	C	S	.	.	H	α-helix	trans	-66.3	-28.5	177.6	72.6	0	0	0	0	113.5	V329 V330 Q335	V329-S333 PolarHBondContact O-N 3.13Å; V330-S333 PolarHBondContact O-N 3.15Å; V330-S333 VanDerWaalsContact O-N 3.15Å; V330-S333 PolarHBondContact O-OG 2.88Å; S333-Q335 VanDerWaalsContact C-N 3.27Å; S333-Q335 PolarHBondContact O-N 3.27Å
334	S	76.1	Confident	80.4	Confident	40 Å²	40	55.5 Å²	55.5	28%	0.28	32%	0.316	S	S	.	.	T	Hydrogen-bonded Turn	trans	-90.2	17.8	174	76.3	0	0	0	0	113.3	V330 L331 L332 A336	V330-S334 PolarHBondContact O-N 3.05Å; L331-S334 PolarHBondContact O-OG 3.01Å; L332-S334 VanDerWaalsContact C-N 3.29Å; L332-S334 PolarHBondContact O-N 2.81Å; S334-A336 PolarHBondContact O-N 3.42Å
335	Q	74.4	Confident	80	Confident	130 Å²	130	56.4 Å²	56.4	61%	0.607	32%	0.316	S	S	*	.	T	Hydrogen-bonded Turn	trans	51.1	16.8	-178.3	-56.3	-172	4.4	0	0	116.1	D250 L332 S333 I337	D250-Q335 PolarHBondContact OD1-NE2 2.89Å; D250-Q335 PolarHBondContact OD2-NE2 2.89Å; D250-Q335 VanDerWaalsContact OD2-NE2 3.08Å; L332-Q335 PolarHBondContact O-N 2.8Å; L332-Q335 VanDerWaalsContact O-N 3.14Å; S333-Q335 VanDerWaalsContact C-N 3.27Å; S333-Q335 PolarHBondContact O-N 3.27Å; Q335-I337 VanDerWaalsContact C-N 3.34Å; Q335-I337 PolarHBondContact O-N 2.89Å
336	A	68.9	Low	79.9	Confident	65 Å²	65	59.2 Å²	59.2	54%	0.537	34%	0.336	S	S	.	.			trans	-78.8	-16.2	-170.7	0	0	0	0	0	113.7	L331 S334	L331-A336 HydrophobicContact CD2-CB 4.25Å; L331-A336 PolarHBondContact O-N 3.18Å; S334-A336 PolarHBondContact O-N 3.42Å
337	I	75.6	Confident	79.9	Confident	77 Å²	77	61.2 Å²	61.2	40%	0.395	34%	0.344	S	S	.	.	S	Bend	trans	-141.6	133.9	-178	-57.8	-177.2	0	0	0	109.9	L331 Q335	L331-I337 HydrophobicContact CB-CD1 4.03Å; L331-I337 HydrophobicContact CB-CG1 4.32Å; L331-I337 HydrophobicContact CD1-CD1 3.89Å; L331-I337 HydrophobicContact CG-CD1 4.42Å; Q335-I337 VanDerWaalsContact C-N 3.34Å; Q335-I337 PolarHBondContact O-N 2.89Å
338	Q	72	Confident	79.9	Confident	180 Å²	180	59.9 Å²	59.9	84%	0.841	34%	0.335	S	S	*	.			trans	-66.2	142	174.2	-66.3	-175.8	-4.3	0	0	112.3	S340	Q338-S340 PolarHBondContact O-N 3.35Å
339	S	69.9	Low	80.1	Confident	61 Å²	61	62.9 Å²	62.9	43%	0.427	35%	0.346	S	S	.	.			trans	-64.6	118.7	-175	67.7	0	0	0	0	113.1
340	S	76.7	Confident	80.6	Confident	43 Å²	43	64.4 Å²	64.4	30%	0.301	35%	0.354	S	S	.	.			trans	-115.4	112.4	174.6	178	0	0	0	0	111.6	Y328 Q338 A342 L343 Y344	Y328-S340 PolarHBondContact OH-N 3Å; Y328-S340 PolarHBondContact OH-O 3.42Å; Q338-S340 PolarHBondContact O-N 3.35Å; S340-A342 PolarHBondContact O-N 2.71Å; S340-L343 PolarHBondContact O-N 2.99Å; S340-Y344 PolarHBondContact O-N 2.97Å
341	N	74.3	Confident	80.9	Confident	126 Å²	126	63.3 Å²	63.3	67%	0.674	35%	0.347	S	S	*	.	H	α-helix	trans	-59.1	-32.5	179.1	-75.9	-71.2	0	0	0	113	F345	N341-F345 WeakPolarHBondContact O-CB 3.22Å; N341-F345 PolarHBondContact O-N 3.04Å
342	A	77.4	Confident	81.4	Confident	64 Å²	64	60 Å²	60	53%	0.529	33%	0.329	S	S	.	.	H	α-helix	trans	-71.9	-45.3	178.2	0	0	0	0	0	111.9	S340 F345 C346	S340-A342 PolarHBondContact O-N 2.71Å; A342-F345 PolarHBondContact O-N 3.29Å; A342-C346 PolarHBondContact O-N 3.49Å; A342-C346 PolarHBondContact O-SG 3.28Å; A342-C346 VanDerWaalsContact O-SG 3.33Å
343	L	81.5	Confident	82.1	Confident	81 Å²	81	57.9 Å²	57.9	42%	0.424	32%	0.319	S	S	.	.	H	α-helix	trans	-65.1	-45.3	176.6	-65.6	178.6	0	0	0	111.2	Y328 S340 F345 C346 F347	Y328-L343 HydrophobicContact CE2-CB 4.16Å; S340-L343 PolarHBondContact O-N 2.99Å; L343-F345 VanDerWaalsContact C-N 3.32Å; L343-F345 PolarHBondContact O-N 3.42Å; L343-C346 PolarHBondContact O-N 3.47Å; L343-F347 HydrophobicContact CB-CE2 4.21Å; L343-F347 WeakPolarHBondContact O-CD2 3.45Å; L343-F347 WeakPolarHBondContact O-CG 3.14Å; L343-F347 PolarHBondContact O-N 2.81Å
344	Y	82.7	Confident	82.9	Confident	42 Å²	42	58 Å²	58	17%	0.165	32%	0.32	C	S	.	.	H	α-helix	trans	-58.6	-42.9	174.5	-176.7	-93.6	0	0	0	111.6	F149 L325 Y328 S340 H348	F149-Y344 AromaticContact CE1-CD1 3.98Å; F149-Y344 HydrophobicContact CE1-CD1 3.98Å; F149-Y344 HydrophobicContact CE1-CE1 4.29Å; F149-Y344 AromaticContact CZ-CD1 3.7Å; F149-Y344 HydrophobicContact CZ-CD1 3.7Å; F149-Y344 AromaticContact CZ-CE1 3.72Å; F149-Y344 HydrophobicContact CZ-CE1 3.72Å; L325-Y344 HydrophobicContact CD1-CD2 4.24Å; L325-Y344 HydrophobicContact CD1-CE2 3.82Å; Y328-Y344 AromaticContact CD1-CD2 3.91Å; Y328-Y344 HydrophobicContact CD1-CD2 3.91Å; Y328-Y344 AromaticContact CE1-CD2 3.72Å; Y328-Y344 HydrophobicContact CE1-CD2 3.72Å; Y328-Y344 HydrophobicContact CE1-CG 4.32Å; S340-Y344 PolarHBondContact O-N 2.97Å; Y344-H348 HydrophobicContact CE1-CB 4.2Å; Y344-H348 AromaticContact CE1-ND1 3.63Å; Y344-H348 AromaticContact CZ-ND1 3.58Å; Y344-H348 WeakPolarHBondContact O-CB 3.45Å; Y344-H348 PolarHBondContact O-N 3.45Å; Y344-H348 PolarHBondContact OH-ND1 2.95Å; Y344-H348 VanDerWaalsContact OH-ND1 3.15Å
345	F	82.9	Confident	83.8	Confident	47 Å²	47	56.2 Å²	56.2	21%	0.206	31%	0.307	C	S	.	.	H	α-helix	trans	-59.2	-51.5	173.6	159.8	-108.2	0	0	0	112	L91 Y95 F149 N341 A342 L343 F347 H348 W349	L91-F345 HydrophobicContact CD2-CD1 4.1Å; L91-F345 HydrophobicContact CD2-CD2 3.37Å; L91-F345 HydrophobicContact CD2-CE1 4.01Å; L91-F345 HydrophobicContact CD2-CE2 3.28Å; L91-F345 HydrophobicContact CD2-CG 3.8Å; L91-F345 HydrophobicContact CD2-CZ 3.62Å; Y95-F345 HydrophobicContact CD2-CE2 4.38Å; Y95-F345 AromaticContact CE2-CD2 3.96Å; Y95-F345 HydrophobicContact CE2-CD2 3.96Å; Y95-F345 AromaticContact CE2-CE2 3.65Å; Y95-F345 HydrophobicContact CE2-CE2 3.65Å; F149-F345 HydrophobicContact CZ-CB 4.45Å; N341-F345 WeakPolarHBondContact O-CB 3.22Å; N341-F345 PolarHBondContact O-N 3.04Å; A342-F345 PolarHBondContact O-N 3.29Å; L343-F345 VanDerWaalsContact C-N 3.32Å; L343-F345 PolarHBondContact O-N 3.42Å; F345-F347 PolarHBondContact O-N 2.98Å; F345-H348 PolarHBondContact O-N 2.71Å; F345-W349 HydrophobicContact CD2-CB 4.26Å; F345-W349 HydrophobicContact CE2-CB 3.67Å; F345-W349 AromaticContact CE2-CD1 4Å; F345-W349 HydrophobicContact CE2-CG 4.02Å; F345-W349 HydrophobicContact CZ-CB 4.04Å; F345-W349 HydrophobicContact CZ-CG 4.13Å; F345-W349 VanDerWaalsContact O-CB 3.31Å; F345-W349 WeakPolarHBondContact O-CB 3.3Å; F345-W349 PolarHBondContact O-N 3.33Å
346	C	88.1	Confident	84.7	Confident	67 Å²	67	50.4 Å²	50.4	45%	0.453	28%	0.281	S	S	.	.	H	α-helix	trans	-59.8	-45.6	-177	-70.4	0	0	0	0	112.1	A342 L343 L350	A342-C346 PolarHBondContact O-N 3.49Å; A342-C346 PolarHBondContact O-SG 3.28Å; A342-C346 VanDerWaalsContact O-SG 3.33Å; L343-C346 PolarHBondContact O-N 3.47Å; C346-L350 WeakPolarHBondContact O-CB 3.42Å; C346-L350 PolarHBondContact O-N 3.47Å
347	F	91.3	Very high	85.8	Confident	58 Å²	58	51.3 Å²	51.3	25%	0.254	27%	0.271	S	S	.	.	H	α-helix	trans	-70.1	-37.6	177.9	-58.7	-29.2	0	0	0	112.5	P324 L325 Y328 L343 F345 A351	P324-F347 HydrophobicContact CB-CB 4.18Å; P324-F347 HydrophobicContact CB-CD1 3.42Å; P324-F347 VanDerWaalsContact CB-CD1 3.42Å; P324-F347 HydrophobicContact CB-CD2 4.41Å; P324-F347 HydrophobicContact CB-CE1 3.83Å; P324-F347 HydrophobicContact CB-CG 3.76Å; P324-F347 HydrophobicContact CB-CZ 4.47Å; L325-F347 HydrophobicContact CB-CB 4.23Å; L325-F347 HydrophobicContact CD1-CB 4.43Å; Y328-F347 AromaticContact CD2-CD2 3.94Å; Y328-F347 HydrophobicContact CD2-CD2 3.94Å; Y328-F347 AromaticContact CD2-CE2 3.81Å; Y328-F347 HydrophobicContact CD2-CE2 3.81Å; Y328-F347 AromaticContact CG-CD2 3.88Å; Y328-F347 HydrophobicContact CG-CD2 3.88Å; Y328-F347 HydrophobicContact CG-CE2 4.18Å; L343-F347 HydrophobicContact CB-CE2 4.21Å; L343-F347 WeakPolarHBondContact O-CD2 3.45Å; L343-F347 WeakPolarHBondContact O-CG 3.14Å; L343-F347 PolarHBondContact O-N 2.81Å; F345-F347 PolarHBondContact O-N 2.98Å; F347-A351 WeakPolarHBondContact O-CB 3.15Å; F347-A351 PolarHBondContact O-N 3.3Å
348	H	88.8	Confident	86.5	Confident	1 Å²	1	48.1 Å²	48.1	1%	0.005	25%	0.254	C	S	.	.	H	α-helix	trans	-66.2	-42.2	174.8	-169.1	121	0	0	0	111.4	Y95 Q168 L325 Y344 F345 A351 M352	Y95-H348 PolarHBondContact OH-CD2 3.48Å; Q168-H348 PolarHBondContact NE2-CE1 3.32Å; L325-H348 HydrophobicContact CD1-CB 4.25Å; Y344-H348 HydrophobicContact CE1-CB 4.2Å; Y344-H348 AromaticContact CE1-ND1 3.63Å; Y344-H348 AromaticContact CZ-ND1 3.58Å; Y344-H348 WeakPolarHBondContact O-CB 3.45Å; Y344-H348 PolarHBondContact O-N 3.45Å; Y344-H348 PolarHBondContact OH-ND1 2.95Å; Y344-H348 VanDerWaalsContact OH-ND1 3.15Å; F345-H348 PolarHBondContact O-N 2.71Å; H348-A351 PolarHBondContact O-N 3.39Å; H348-M352 VanDerWaalsContact CD2-CG 3.43Å; H348-M352 WeakPolarHBondContact CD2-CG 3.31Å; H348-M352 WeakPolarHBondContact O-CB 3.37Å; H348-M352 WeakPolarHBondContact O-CG 3.38Å; H348-M352 PolarHBondContact O-N 2.84Å
349	W	91.2	Very high	87.2	Confident	76 Å²	76	39.8 Å²	39.8	29%	0.288	22%	0.216	S	C	.	.	H	α-helix	trans	-64.6	-42.5	178.1	-177	86.7	0	0	0	111.8	A94 I98 F345 M352 S353	A94-W349 PolarHBondContact O-NE1 3.24Å; I98-W349 HydrophobicContact CD1-CD2 4.1Å; I98-W349 HydrophobicContact CD1-CG 4.16Å; I98-W349 HydrophobicContact CD1-CZ2 4.06Å; I98-W349 HydrophobicContact CG1-CZ2 4.46Å; F345-W349 HydrophobicContact CD2-CB 4.26Å; F345-W349 HydrophobicContact CE2-CB 3.67Å; F345-W349 AromaticContact CE2-CD1 4Å; F345-W349 HydrophobicContact CE2-CG 4.02Å; F345-W349 HydrophobicContact CZ-CB 4.04Å; F345-W349 HydrophobicContact CZ-CG 4.13Å; F345-W349 VanDerWaalsContact O-CB 3.31Å; F345-W349 WeakPolarHBondContact O-CB 3.3Å; F345-W349 PolarHBondContact O-N 3.33Å; W349-M352 PolarHBondContact O-N 3.49Å; W349-S353 PolarHBondContact O-N 2.89Å
350	L	93.9	Very high	88	Confident	53 Å²	53	40 Å²	40	28%	0.277	21%	0.209	S	C	.	.	H	α-helix	trans	-63.9	-39.6	174.2	178.1	60.8	0	0	0	112.2	C321 P324 C346 S353	C321-L350 WeakPolarHBondContact CB-O 3.07Å; P324-L350 HydrophobicContact CG-CD2 4.08Å; C346-L350 WeakPolarHBondContact O-CB 3.42Å; C346-L350 PolarHBondContact O-N 3.47Å; L350-S353 PolarHBondContact O-N 3.24Å; L350-S353 PolarHBondContact O-OG 2.95Å
351	A	93.1	Very high	88.5	Confident	0 Å²	0	38.9 Å²	38.9	0%	0	20%	0.2	C	C	.	.	H	α-helix	trans	-63.9	-43.9	172.4	0	0	0	0	0	111.8	C321 W322 L325 F347 H348 S353 S354	C321-A351 WeakPolarHBondContact O-CA 3.4Å; C321-A351 PolarHBondContact O-N 3.5Å; W322-A351 HydrophobicContact CD2-CB 3.82Å; W322-A351 HydrophobicContact CE3-CB 3.73Å; W322-A351 HydrophobicContact CG-CB 4.39Å; W322-A351 HydrophobicContact CH2-CB 4.41Å; W322-A351 HydrophobicContact CZ2-CB 4.44Å; W322-A351 HydrophobicContact CZ3-CB 4.06Å; W322-A351 PolarHBondContact NE1-O 3.39Å; L325-A351 HydrophobicContact CB-CB 4.09Å; L325-A351 HydrophobicContact CD2-CB 3.62Å; F347-A351 WeakPolarHBondContact O-CB 3.15Å; F347-A351 PolarHBondContact O-N 3.3Å; H348-A351 PolarHBondContact O-N 3.39Å; A351-S353 VanDerWaalsContact C-N 3.33Å; A351-S353 PolarHBondContact O-N 3.44Å; A351-S354 VanDerWaalsContact O-CB 3.29Å; A351-S354 WeakPolarHBondContact O-CB 3.48Å; A351-S354 PolarHBondContact O-N 2.99Å; A351-S354 PolarHBondContact O-OG 3.47Å
352	M	93.7	Very high	89	Confident	0 Å²	0	33.2 Å²	33.2	0%	0	17%	0.169	C	C	.	.	H	α-helix	trans	-66.5	-31.8	178.6	-69.5	-63.5	127.8	0	0	112.9	Y95 I98 I137 M142 Q168 W322 H348 W349 S354 T355	Y95-M352 HydrophobicContact CE1-CG 4.32Å; I98-M352 HydrophobicContact CD1-CB 4.36Å; I137-M352 HydrophobicContact CD1-CE 3.67Å; I137-M352 HydrophobicContact CD1-SD 4.05Å; I137-M352 HydrophobicContact CG1-CE 4.27Å; I137-M352 HydrophobicContact CG1-SD 4.13Å; M142-M352 HydrophobicContact CE-CB 3.89Å; M142-M352 HydrophobicContact CE-CG 4.3Å; M142-M352 WeakPolarHBondContact CE-O 3.23Å; M142-M352 HydrophobicContact CE-SD 3.72Å; M142-M352 HydrophobicContact CG-CB 4.5Å; M142-M352 HydrophobicContact CG-CG 4.19Å; M142-M352 HydrophobicContact CG-SD 3.6Å; M142-M352 VanDerWaalsContact CG-SD 3.6Å; M142-M352 HydrophobicContact SD-CB 4.32Å; M142-M352 HydrophobicContact SD-SD 4.36Å; Q168-M352 HydrophobicContact CG-CE 4.31Å; W322-M352 HydrophobicContact CH2-CE 3.91Å; H348-M352 VanDerWaalsContact CD2-CG 3.43Å; H348-M352 WeakPolarHBondContact CD2-CG 3.31Å; H348-M352 WeakPolarHBondContact O-CB 3.37Å; H348-M352 WeakPolarHBondContact O-CG 3.38Å; H348-M352 PolarHBondContact O-N 2.84Å; W349-M352 PolarHBondContact O-N 3.49Å; M352-S354 PolarHBondContact O-N 3.34Å; M352-T355 PolarHBondContact O-N 3.24Å; M352-T355 PolarHBondContact O-OG1 2.76Å
353	S	94.6	Very high	89.2	Confident	3 Å²	3	30.7 Å²	30.7	2%	0.021	15%	0.147	C	C	.	.	H	α-helix	trans	-67.1	-17.8	178.3	77.9	0	0	0	0	112.9	W349 L350 A351 T355 C356 Y357	W349-S353 PolarHBondContact O-N 2.89Å; L350-S353 PolarHBondContact O-N 3.24Å; L350-S353 PolarHBondContact O-OG 2.95Å; A351-S353 VanDerWaalsContact C-N 3.33Å; A351-S353 PolarHBondContact O-N 3.44Å; S353-T355 PolarHBondContact O-N 2.96Å; S353-T355 VanDerWaalsContact O-N 3.15Å; S353-C356 VanDerWaalsContact O-CB 3.31Å; S353-C356 WeakPolarHBondContact O-CB 3.37Å; S353-C356 PolarHBondContact O-N 3.33Å; S353-Y357 WeakPolarHBondContact CB-OH 3.14Å; S353-Y357 VanDerWaalsContact O-CD2 3.3Å; S353-Y357 WeakPolarHBondContact O-CD2 3.33Å; S353-Y357 WeakPolarHBondContact O-CE2 3.22Å; S353-Y357 WeakPolarHBondContact OG-CE2 3.46Å; S353-Y357 PolarHBondContact OG-OH 3.32Å
354	S	94.2	Very high	88.9	Confident	5 Å²	5	29 Å²	29	4%	0.035	14%	0.142	C	C	.	.	H	α-helix	trans	-51.8	-40.5	177	80.1	0	0	0	0	112.5	W322 A351 M352 C356 Y357	W322-S354 PolarHBondContact NE1-OG 3.33Å; A351-S354 VanDerWaalsContact O-CB 3.29Å; A351-S354 WeakPolarHBondContact O-CB 3.48Å; A351-S354 PolarHBondContact O-N 2.99Å; A351-S354 PolarHBondContact O-OG 3.47Å; M352-S354 PolarHBondContact O-N 3.34Å; S354-C356 PolarHBondContact O-N 3.14Å; S354-Y357 PolarHBondContact O-N 2.94Å
355	T	94.5	Very high	88.4	Confident	1 Å²	1	29.4 Å²	29.4	1%	0.006	15%	0.147	C	C	.	.	H	α-helix	trans	-58.2	-28.6	-179.9	62.7	0	0	0	0	113.2	S102 N106 D134 I137 M142 M352 S353	S102-T355 WeakPolarHBondContact CB-OG1 3.21Å; S102-T355 WeakPolarHBondContact OG-CB 3.47Å; S102-T355 PolarHBondContact OG-OG1 3.33Å; N106-T355 PolarHBondContact ND2-O 2.77Å; D134-T355 HydrophobicContact CB-CG2 4.13Å; I137-T355 HydrophobicContact CG2-CG2 3.84Å; M142-T355 HydrophobicContact CE-CG2 3.76Å; M352-T355 PolarHBondContact O-N 3.24Å; M352-T355 PolarHBondContact O-OG1 2.76Å; S353-T355 PolarHBondContact O-N 2.96Å; S353-T355 VanDerWaalsContact O-N 3.15Å
356	C	93.8	Very high	88	Confident	9 Å²	9	28.7 Å²	28.7	6%	0.061	15%	0.145	C	C	.	.	H	α-helix	trans	-75.4	-32.9	-179.6	-68.6	0	0	0	0	112.8	I98 I101 S353 S354 P359 F360	I98-C356 PolarHBondContact O-SG 3.27Å; I98-C356 VanDerWaalsContact O-SG 3.39Å; I101-C356 HydrophobicContact CG2-CB 3.73Å; S353-C356 VanDerWaalsContact O-CB 3.31Å; S353-C356 WeakPolarHBondContact O-CB 3.37Å; S353-C356 PolarHBondContact O-N 3.33Å; S354-C356 PolarHBondContact O-N 3.14Å; C356-P359 WeakPolarHBondContact O-CD 3.27Å; C356-F360 WeakPolarHBondContact O-CD2 3.28Å; C356-F360 WeakPolarHBondContact O-CE2 3.39Å
357	Y	92.1	Very high	87.3	Confident	84 Å²	84	28.9 Å²	28.9	33%	0.329	15%	0.145	S	C	.	.	H	α-helix	trans	-79.8	-28.7	-166.6	-52.6	-59.5	0	0	0	113.7	V317 S353 S354 F360 I361	V317-Y357 HydrophobicContact CG1-CD2 3.3Å; V317-Y357 HydrophobicContact CG1-CE2 4.1Å; V317-Y357 HydrophobicContact CG1-CG 3.86Å; S353-Y357 WeakPolarHBondContact CB-OH 3.14Å; S353-Y357 VanDerWaalsContact O-CD2 3.3Å; S353-Y357 WeakPolarHBondContact O-CD2 3.33Å; S353-Y357 WeakPolarHBondContact O-CE2 3.22Å; S353-Y357 WeakPolarHBondContact OG-CE2 3.46Å; S353-Y357 PolarHBondContact OG-OH 3.32Å; S354-Y357 PolarHBondContact O-N 2.94Å; Y357-F360 PolarHBondContact O-N 3.48Å; Y357-I361 WeakPolarHBondContact O-CG1 3.29Å; Y357-I361 PolarHBondContact O-N 2.99Å
358	N	88.8	Confident	86.4	Confident	9 Å²	9	27.8 Å²	27.8	5%	0.048	15%	0.147	C	C	.	.	H	α-helix	trans	-50.2	-52	-177.7	-73.9	-27.5	0	0	0	112.7	D134 V314 F360 I361 Y362	D134-N358 PolarHBondContact OD2-ND2 3.38Å; V314-N358 WeakPolarHBondContact CG1-OD1 3.48Å; N358-F360 PolarHBondContact O-N 3.33Å; N358-I361 PolarHBondContact O-N 2.87Å; N358-Y362 HydrophobicContact CB-CE2 4.29Å; N358-Y362 WeakPolarHBondContact O-CD2 3.08Å; N358-Y362 VanDerWaalsContact O-CG 3.3Å; N358-Y362 PolarHBondContact O-N 2.91Å; N358-Y362 VanDerWaalsContact O-N 3.12Å
359	P	87.6	Confident	85.8	Confident	5 Å²	5	27.8 Å²	27.8	3%	0.032	15%	0.147	C	C	.	.	H	α-helix	trans	-55.1	-43.5	172.8	-28	34.3	0	0	0	115	G105 N106 V109 C356 Y362 C363	G105-P359 WeakPolarHBondContact O-CG 3.49Å; N106-P359 WeakPolarHBondContact OD1-CG 3.44Å; V109-P359 HydrophobicContact CG2-CB 4.08Å; V109-P359 HydrophobicContact CG2-CG 4.03Å; C356-P359 WeakPolarHBondContact O-CD 3.27Å; P359-Y362 PolarHBondContact O-N 3.32Å; P359-C363 WeakPolarHBondContact O-CB 3.05Å; P359-C363 PolarHBondContact O-N 3.4Å; P359-C363 PolarHBondContact O-SG 2.96Å; P359-C363 VanDerWaalsContact O-SG 3.37Å
360	F	87.3	Confident	85.3	Confident	66 Å²	66	25.4 Å²	25.4	29%	0.289	14%	0.138	S	C	.	.	H	α-helix	trans	-66	-42.3	179.5	-65.7	-101.8	0	0	0	111.6	W7 T11 I101 C356 Y357 N358 Y362 C363 C364	W7-F360 HydrophobicContact CH2-CE1 4.34Å; W7-F360 AromaticContact CH2-CE2 3.97Å; W7-F360 HydrophobicContact CH2-CE2 3.97Å; W7-F360 AromaticContact CH2-CZ 3.69Å; W7-F360 HydrophobicContact CH2-CZ 3.69Å; W7-F360 HydrophobicContact CZ2-CE1 4.25Å; W7-F360 HydrophobicContact CZ2-CE2 4.09Å; W7-F360 AromaticContact CZ2-CZ 3.49Å; W7-F360 HydrophobicContact CZ2-CZ 3.49Å; W7-F360 VanDerWaalsContact CZ2-CZ 3.49Å; T11-F360 HydrophobicContact CG2-CD1 4.18Å; T11-F360 HydrophobicContact CG2-CE1 3.57Å; T11-F360 HydrophobicContact CG2-CZ 4.19Å; I101-F360 HydrophobicContact CG2-CE2 3.87Å; I101-F360 HydrophobicContact CG2-CZ 4.31Å; C356-F360 WeakPolarHBondContact O-CD2 3.28Å; C356-F360 WeakPolarHBondContact O-CE2 3.39Å; Y357-F360 PolarHBondContact O-N 3.48Å; N358-F360 PolarHBondContact O-N 3.33Å; F360-Y362 VanDerWaalsContact C-N 3.29Å; F360-Y362 PolarHBondContact O-N 2.98Å; F360-C363 WeakPolarHBondContact O-CB 3.34Å; F360-C363 PolarHBondContact O-N 3.33Å; F360-C363 VanDerWaalsContact O-N 3.16Å; F360-C364 PolarHBondContact O-N 2.84Å; F360-C364 PolarHBondContact O-SG 3.22Å
361	I	87.2	Confident	84.6	Confident	20 Å²	20	28.5 Å²	28.5	10%	0.103	15%	0.151	C	C	.	.	H	α-helix	trans	-63.2	-40	180	-62	164.8	0	0	0	110	M310 A313 V314 V317 Y357 N358 L365	M310-I361 HydrophobicContact CG-CG2 3.96Å; A313-I361 HydrophobicContact CB-CG2 4.01Å; V314-I361 HydrophobicContact CG2-CB 4.17Å; V314-I361 HydrophobicContact CG2-CD1 4.06Å; V314-I361 HydrophobicContact CG2-CG2 3.68Å; V317-I361 HydrophobicContact CB-CD1 4.39Å; V317-I361 HydrophobicContact CG2-CD1 4.19Å; Y357-I361 WeakPolarHBondContact O-CG1 3.29Å; Y357-I361 PolarHBondContact O-N 2.99Å; N358-I361 PolarHBondContact O-N 2.87Å; I361-L365 HydrophobicContact CG2-CD1 4.25Å; I361-L365 WeakPolarHBondContact O-CB 3.24Å; I361-L365 PolarHBondContact O-N 3.26Å
362	Y	84.3	Confident	83.9	Confident	7 Å²	7	29.6 Å²	29.6	3%	0.027	16%	0.156	C	C	.	.	H	α-helix	trans	-66.9	-43.2	172	-56.7	-31.4	0	0	0	112.4	V109 I127 M310 V314 N358 P359 F360 N366	V109-Y362 HydrophobicContact CG1-CD2 4.27Å; V109-Y362 HydrophobicContact CG1-CE2 4.28Å; V109-Y362 HydrophobicContact CG2-CD2 3.9Å; V109-Y362 HydrophobicContact CG2-CE2 4.44Å; I127-Y362 HydrophobicContact CG2-CD2 4.37Å; I127-Y362 HydrophobicContact CG2-CE2 3.81Å; M310-Y362 HydrophobicContact CE-CD1 4.22Å; M310-Y362 HydrophobicContact CE-CE1 4.35Å; M310-Y362 HydrophobicContact CG-CD1 4.34Å; M310-Y362 HydrophobicContact SD-CD1 3.96Å; V314-Y362 HydrophobicContact CG2-CE1 3.91Å; N358-Y362 HydrophobicContact CB-CE2 4.29Å; N358-Y362 WeakPolarHBondContact O-CD2 3.08Å; N358-Y362 VanDerWaalsContact O-CG 3.3Å; N358-Y362 PolarHBondContact O-N 2.91Å; N358-Y362 VanDerWaalsContact O-N 3.12Å; P359-Y362 PolarHBondContact O-N 3.32Å; F360-Y362 VanDerWaalsContact C-N 3.29Å; F360-Y362 PolarHBondContact O-N 2.98Å; Y362-N366 VanDerWaalsContact O-CB 3.24Å; Y362-N366 WeakPolarHBondContact O-CB 3.22Å; Y362-N366 PolarHBondContact O-N 3.48Å
363	C	80.9	Confident	83.1	Confident	10 Å²	10	29.8 Å²	29.8	7%	0.068	16%	0.157	C	C	.	.	H	α-helix	trans	-57.4	-49.1	173.9	-79.8	0	0	0	0	112.5	P359 F360 F369 R370	P359-C363 WeakPolarHBondContact O-CB 3.05Å; P359-C363 PolarHBondContact O-N 3.4Å; P359-C363 PolarHBondContact O-SG 2.96Å; P359-C363 VanDerWaalsContact O-SG 3.37Å; F360-C363 WeakPolarHBondContact O-CB 3.34Å; F360-C363 PolarHBondContact O-N 3.33Å; F360-C363 VanDerWaalsContact O-N 3.16Å; C363-F369 VanDerWaalsContact SG-CE1 3.58Å; C363-R370 WeakPolarHBondContact O-CD 3.45Å; C363-R370 WeakPolarHBondContact O-CG 3.26Å
364	C	75.9	Confident	82.4	Confident	45 Å²	45	35.1 Å²	35.1	30%	0.304	18%	0.177	S	C	.	.	H	α-helix	trans	-68.8	-42.9	-178	-68.4	0	0	0	0	111.8	R306 F360	R306-C364 PolarHBondContact NH2-O 2.97Å; F360-C364 PolarHBondContact O-N 2.84Å; F360-C364 PolarHBondContact O-SG 3.22Å
365	L	71.6	Confident	81.7	Confident	52 Å²	52	38.9 Å²	38.9	27%	0.272	19%	0.194	S	C	.	.	H	α-helix	trans	-108.7	-13.8	-163.2	-59.1	175.7	0	0	0	115.5	R306 M310 I361 P367	R306-L365 WeakPolarHBondContact CD-O 3.46Å; R306-L365 WeakPolarHBondContact CG-O 3.12Å; R306-L365 PolarHBondContact NE-O 2.95Å; M310-L365 HydrophobicContact CB-CB 3.73Å; M310-L365 HydrophobicContact CB-CD1 3.98Å; M310-L365 HydrophobicContact CG-CB 3.8Å; M310-L365 HydrophobicContact CG-CD1 4.37Å; M310-L365 HydrophobicContact SD-CB 4.33Å; I361-L365 HydrophobicContact CG2-CD1 4.25Å; I361-L365 WeakPolarHBondContact O-CB 3.24Å; I361-L365 PolarHBondContact O-N 3.26Å; L365-P367 WeakPolarHBondContact O-CD 3.45Å
366	N	75.8	Confident	80.8	Confident	31 Å²	31	40 Å²	40	17%	0.166	20%	0.2	C	C	.	.			trans	-102.8	105.1	174.5	-174.6	-6.7	0	0	0	112.4	M310 Y362 A368 F369 R370	M310-N366 HydrophobicContact SD-CB 3.94Å; Y362-N366 VanDerWaalsContact O-CB 3.24Å; Y362-N366 WeakPolarHBondContact O-CB 3.22Å; Y362-N366 PolarHBondContact O-N 3.48Å; N366-A368 VanDerWaalsContact C-N 3.3Å; N366-A368 PolarHBondContact O-N 2.96Å; N366-A368 PolarHBondContact OD1-N 2.98Å; N366-A368 VanDerWaalsContact OD1-N 3.14Å; N366-F369 HydrophobicContact CB-CB 3.9Å; N366-F369 WeakPolarHBondContact O-CB 3.31Å; N366-F369 PolarHBondContact O-N 3.41Å; N366-R370 PolarHBondContact O-N 3.14Å; N366-R370 VanDerWaalsContact O-N 3.15Å
367	P	73.6	Confident	79.9	Confident	72 Å²	72	40.2 Å²	40.2	47%	0.468	20%	0.2	S	C	.	.	H	α-helix	trans	-63.8	-28.9	-178.5	-23.3	35.2	0	0	0	114.7	L365 R370 Q371	L365-P367 WeakPolarHBondContact O-CD 3.45Å; P367-R370 PolarHBondContact O-N 3.48Å; P367-Q371 PolarHBondContact O-N 2.98Å; P367-Q371 VanDerWaalsContact O-N 3.08Å
368	A	72.6	Confident	78.9	Confident	34 Å²	34	37.2 Å²	37.2	28%	0.281	20%	0.195	S	C	.	.	H	α-helix	trans	-69.1	-41.1	177.1	0	0	0	0	0	110.8	M119 N366 R370 Q371 E372	M119-A368 HydrophobicContact CG-CB 4.47Å; M119-A368 HydrophobicContact SD-CB 3.84Å; N366-A368 VanDerWaalsContact C-N 3.3Å; N366-A368 PolarHBondContact O-N 2.96Å; N366-A368 PolarHBondContact OD1-N 2.98Å; N366-A368 VanDerWaalsContact OD1-N 3.14Å; A368-R370 PolarHBondContact O-N 2.93Å; A368-Q371 PolarHBondContact O-N 3.15Å; A368-Q371 VanDerWaalsContact O-N 3.08Å; A368-E372 PolarHBondContact O-N 3.46Å; A368-E372 VanDerWaalsContact O-N 3.08Å
369	F	75.4	Confident	77.5	Confident	2 Å²	2	41.3 Å²	41.3	1%	0.009	22%	0.215	C	C	.	.	H	α-helix	trans	-59.5	-46.1	173.1	-159.7	-85.7	0	0	0	111.1	L108 V109 V112 C363 N366 Q371 E372 L373	L108-F369 HydrophobicContact CG-CZ 4.42Å; V109-F369 HydrophobicContact CB-CE2 4.41Å; V109-F369 HydrophobicContact CB-CZ 4.46Å; V109-F369 HydrophobicContact CG2-CE2 4.05Å; V109-F369 HydrophobicContact CG2-CZ 3.83Å; V112-F369 HydrophobicContact CB-CD2 4.13Å; V112-F369 HydrophobicContact CB-CE2 3.65Å; V112-F369 HydrophobicContact CB-CZ 4.05Å; V112-F369 HydrophobicContact CG1-CD2 3.52Å; V112-F369 HydrophobicContact CG1-CE2 3.59Å; V112-F369 HydrophobicContact CG1-CG 4.12Å; V112-F369 HydrophobicContact CG1-CZ 4.25Å; V112-F369 HydrophobicContact CG2-CE2 4.16Å; V112-F369 HydrophobicContact CG2-CZ 4.05Å; C363-F369 VanDerWaalsContact SG-CE1 3.58Å; N366-F369 HydrophobicContact CB-CB 3.9Å; N366-F369 WeakPolarHBondContact O-CB 3.31Å; N366-F369 PolarHBondContact O-N 3.41Å; F369-Q371 PolarHBondContact O-N 3.34Å; F369-E372 PolarHBondContact O-N 3.08Å; F369-L373 VanDerWaalsContact O-CB 3.27Å; F369-L373 WeakPolarHBondContact O-CB 3.36Å; F369-L373 PolarHBondContact O-N 3.43Å
370	R	80.4	Confident	76.1	Confident	25 Å²	25	44 Å²	44	9%	0.094	23%	0.232	C	C	.	.	H	α-helix	trans	-60.7	-25.8	173.6	-68.8	-179.2	65.7	153.9	-1.9	114.5	A15 C363 N366 P367 A368 R374	A15-R370 VanDerWaalsContact O-CZ 3.27Å; A15-R370 PolarHBondContact O-NH1 3.42Å; A15-R370 PolarHBondContact O-NH2 2.94Å; C363-R370 WeakPolarHBondContact O-CD 3.45Å; C363-R370 WeakPolarHBondContact O-CG 3.26Å; N366-R370 PolarHBondContact O-N 3.14Å; N366-R370 VanDerWaalsContact O-N 3.15Å; P367-R370 PolarHBondContact O-N 3.48Å; A368-R370 PolarHBondContact O-N 2.93Å; R370-R374 WeakPolarHBondContact O-CB 3.35Å; R370-R374 WeakPolarHBondContact O-CG 3.27Å; R370-R374 PolarHBondContact O-N 3.25Å; R370-R374 PolarHBondContact O-NE 3.32Å
371	Q	78.9	Confident	74.8	Confident	119 Å²	119	47.2 Å²	47.2	56%	0.556	25%	0.249	S	C	*	.	H	α-helix	trans	-81.4	-44.8	-179.8	-172.2	171.2	6.4	0	0	110.9	P367 A368 F369 R374 Q375	P367-Q371 PolarHBondContact O-N 2.98Å; P367-Q371 VanDerWaalsContact O-N 3.08Å; A368-Q371 PolarHBondContact O-N 3.15Å; A368-Q371 VanDerWaalsContact O-N 3.08Å; F369-Q371 PolarHBondContact O-N 3.34Å; Q371-R374 PolarHBondContact O-N 3Å; Q371-Q375 WeakPolarHBondContact O-CG 3.23Å; Q371-Q375 PolarHBondContact O-N 3.27Å; Q371-Q375 VanDerWaalsContact O-N 3.14Å; Q371-Q375 PolarHBondContact O-NE2 3.18Å
372	E	78.4	Confident	73.3	Confident	23 Å²	23	56.1 Å²	56.1	11%	0.107	28%	0.281	C	S	.	.	H	α-helix	trans	-63.6	-41.4	172.2	-66.2	-54	126.6	0	0	111.7	V112 K115 N116 A368 F369 R374 Q375 L376	V112-E372 HydrophobicContact CG1-CB 3.74Å; V112-E372 HydrophobicContact CG1-CG 4.2Å; K115-E372 IonicContact NZ-OE2 3.99Å; N116-E372 HydrophobicContact CB-CG 4.06Å; N116-E372 VanDerWaalsContact ND2-CG 3.27Å; N116-E372 WeakPolarHBondContact ND2-CG 3.33Å; N116-E372 PolarHBondContact ND2-OE1 3.2Å; A368-E372 PolarHBondContact O-N 3.46Å; A368-E372 VanDerWaalsContact O-N 3.08Å; F369-E372 PolarHBondContact O-N 3.08Å; E372-R374 VanDerWaalsContact C-N 3.32Å; E372-R374 PolarHBondContact O-N 2.83Å; E372-Q375 WeakPolarHBondContact O-CB 3.42Å; E372-Q375 PolarHBondContact O-N 3.25Å; E372-Q375 VanDerWaalsContact O-N 3.09Å; E372-Q375 PolarHBondContact OE1-NE2 3.21Å; E372-L376 WeakPolarHBondContact O-CG 3.35Å; E372-L376 PolarHBondContact O-N 3.02Å
373	L	78.1	Confident	71.7	Confident	4 Å²	4	66.7 Å²	66.7	2%	0.021	32%	0.321	C	S	.	.	H	α-helix	trans	-62.2	-39	178.1	-168.5	60.1	0	0	0	112.4	L8 L108 F369 L376 L377	L8-L373 HydrophobicContact CD2-CD1 3.81Å; L8-L373 HydrophobicContact CD2-CD2 4.47Å; L108-L373 HydrophobicContact CD1-CD1 3.8Å; L108-L373 HydrophobicContact CD2-CD1 3.85Å; L108-L373 HydrophobicContact CG-CD1 4.28Å; F369-L373 VanDerWaalsContact O-CB 3.27Å; F369-L373 WeakPolarHBondContact O-CB 3.36Å; F369-L373 PolarHBondContact O-N 3.43Å; L373-L376 HydrophobicContact CD1-CD1 4.5Å; L373-L376 PolarHBondContact O-N 3.22Å; L373-L377 HydrophobicContact CG-CD1 4.5Å; L373-L377 WeakPolarHBondContact O-CB 3.45Å; L373-L377 PolarHBondContact O-N 3.25Å
374	R	79.3	Confident	70.3	Confident	114 Å²	114	69.5 Å²	69.5	43%	0.43	35%	0.351	S	S	.	.	H	α-helix	trans	-65.4	-35.4	172.8	-84.9	-178.9	-80.9	-171.3	1.5	112.9	Y12 R370 Q371 E372 G378	Y12-R374 HydrophobicContact CD2-CG 4.23Å; Y12-R374 HydrophobicContact CE2-CG 3.57Å; R370-R374 WeakPolarHBondContact O-CB 3.35Å; R370-R374 WeakPolarHBondContact O-CG 3.27Å; R370-R374 PolarHBondContact O-N 3.25Å; R370-R374 PolarHBondContact O-NE 3.32Å; Q371-R374 PolarHBondContact O-N 3Å; E372-R374 VanDerWaalsContact C-N 3.32Å; E372-R374 PolarHBondContact O-N 2.83Å; R374-G378 PolarHBondContact O-N 3.29Å
375	Q	80	Confident	69	Low	85 Å²	85	77.8 Å²	77.8	40%	0.397	38%	0.376	S	S	.	.	H	α-helix	trans	-66.2	-43.7	172.8	-68.5	171.4	58	0	0	111.4	Q371 E372 G378 M379	Q371-Q375 WeakPolarHBondContact O-CG 3.23Å; Q371-Q375 PolarHBondContact O-N 3.27Å; Q371-Q375 VanDerWaalsContact O-N 3.14Å; Q371-Q375 PolarHBondContact O-NE2 3.18Å; E372-Q375 WeakPolarHBondContact O-CB 3.42Å; E372-Q375 PolarHBondContact O-N 3.25Å; E372-Q375 VanDerWaalsContact O-N 3.09Å; E372-Q375 PolarHBondContact OE1-NE2 3.21Å; Q375-G378 PolarHBondContact O-N 3.45Å; Q375-M379 WeakPolarHBondContact O-CG 3.37Å; Q375-M379 PolarHBondContact O-N 3.45Å
376	L	74.6	Confident	68	Low	25 Å²	25	78.4 Å²	78.4	13%	0.131	40%	0.395	C	S	.	.	H	α-helix	trans	-60.3	-48.3	176	-66.9	168.4	0	0	0	111.3	L108 V112 E372 L373 M379 C380	L108-L376 HydrophobicContact CD1-CD1 4.22Å; V112-L376 HydrophobicContact CG2-CD1 3.71Å; E372-L376 WeakPolarHBondContact O-CG 3.35Å; E372-L376 PolarHBondContact O-N 3.02Å; L373-L376 HydrophobicContact CD1-CD1 4.5Å; L373-L376 PolarHBondContact O-N 3.22Å; L376-M379 HydrophobicContact CD2-CE 3.83Å; L376-M379 PolarHBondContact O-N 3.35Å; L376-C380 PolarHBondContact O-N 3.35Å; L376-C380 PolarHBondContact O-SG 2.89Å; L376-C380 VanDerWaalsContact O-SG 3.39Å
377	L	75.6	Confident	66.6	Low	13 Å²	13	80.6 Å²	80.6	7%	0.068	43%	0.425	C	S	.	.	H	α-helix	trans	-59.4	-46.5	174.2	-84.9	168.3	0	0	0	112.6	L8 L373 M379 C380 Q381	L8-L377 HydrophobicContact CB-CD1 4.38Å; L8-L377 HydrophobicContact CB-CD2 3.69Å; L8-L377 HydrophobicContact CB-CG 4.24Å; L8-L377 HydrophobicContact CD1-CD2 4.28Å; L373-L377 HydrophobicContact CG-CD1 4.5Å; L373-L377 WeakPolarHBondContact O-CB 3.45Å; L373-L377 PolarHBondContact O-N 3.25Å; L377-M379 VanDerWaalsContact C-N 3.31Å; L377-M379 PolarHBondContact O-N 3.49Å; L377-C380 WeakPolarHBondContact O-CB 3.46Å; L377-C380 PolarHBondContact O-N 3.39Å; L377-C380 VanDerWaalsContact O-N 3.15Å; L377-Q381 WeakPolarHBondContact O-CG 3.48Å; L377-Q381 PolarHBondContact O-N 3.45Å
378	G	69.9	Low	65.5	Low	21 Å²	21	83.2 Å²	83.2	22%	0.216	44%	0.439	C	S	.	.	H	α-helix	trans	-63.2	-34.3	178.1	0	0	0	0	0	113.3	R374 Q375 R382	R374-G378 PolarHBondContact O-N 3.29Å; Q375-G378 PolarHBondContact O-N 3.45Å; G378-R382 WeakPolarHBondContact O-CB 3.5Å; G378-R382 VanDerWaalsContact O-CG 3.28Å; G378-R382 WeakPolarHBondContact O-CG 3.45Å; G378-R382 PolarHBondContact O-N 3.36Å
379	M	60.9	Low	63.8	Low	95 Å²	95	84.7 Å²	84.7	47%	0.468	46%	0.458	S	S	.	.	H	α-helix	trans	-69	-40.4	171.6	-72.2	-175.7	-60.3	0	0	112	Q375 L376 L377 R382 R383	Q375-M379 WeakPolarHBondContact O-CG 3.37Å; Q375-M379 PolarHBondContact O-N 3.45Å; L376-M379 HydrophobicContact CD2-CE 3.83Å; L376-M379 PolarHBondContact O-N 3.35Å; L377-M379 VanDerWaalsContact C-N 3.31Å; L377-M379 PolarHBondContact O-N 3.49Å; M379-R382 PolarHBondContact O-N 3.34Å; M379-R383 WeakPolarHBondContact O-CB 3.47Å; M379-R383 PolarHBondContact O-N 3.12Å
380	C	57.6	Low	62.3	Low	60 Å²	60	90.5 Å²	90.5	41%	0.405	50%	0.496	S	S	.	.	H	α-helix	trans	-62.1	-42.7	173.3	-69.2	0	0	0	0	112.1	L376 L377 R383 G384	L376-C380 PolarHBondContact O-N 3.35Å; L376-C380 PolarHBondContact O-SG 2.89Å; L376-C380 VanDerWaalsContact O-SG 3.39Å; L377-C380 WeakPolarHBondContact O-CB 3.46Å; L377-C380 PolarHBondContact O-N 3.39Å; L377-C380 VanDerWaalsContact O-N 3.15Å; C380-R383 PolarHBondContact O-N 3.21Å; C380-G384 PolarHBondContact O-N 3.48Å
381	Q	60.3	Low	60.5	Low	135 Å²	135	95.6 Å²	95.6	63%	0.631	53%	0.529	S	S	*	.	H	α-helix	trans	-62.9	-44.9	175.4	-72.2	172.5	-13.4	0	0	112	L377 G384 R385	L377-Q381 WeakPolarHBondContact O-CG 3.48Å; L377-Q381 PolarHBondContact O-N 3.45Å; Q381-G384 PolarHBondContact O-N 3.19Å; Q381-R385 PolarHBondContact O-N 3.49Å
382	R	55.2	Low	58.8	Low	206 Å²	206	98.1 Å²	98.1	78%	0.777	55%	0.546	S	S	*	.	H	α-helix	trans	-62.5	-43.6	175.1	-74.1	173.7	-177.9	-165.2	-1.1	112	G378 M379 G384 R385 G386	G378-R382 WeakPolarHBondContact O-CB 3.5Å; G378-R382 VanDerWaalsContact O-CG 3.28Å; G378-R382 WeakPolarHBondContact O-CG 3.45Å; G378-R382 PolarHBondContact O-N 3.36Å; M379-R382 PolarHBondContact O-N 3.34Å; R382-G384 VanDerWaalsContact C-N 3.27Å; R382-G384 PolarHBondContact O-N 3.19Å; R382-R385 PolarHBondContact O-N 2.88Å; R382-G386 PolarHBondContact O-N 3.3Å
383	R	51	Low	57	Low	229 Å²	229	103.1 Å²	103.1	86%	0.864	58%	0.578	S	S	*	*	H	α-helix	trans	-68.2	-25.6	178.4	-161.1	168.5	-173.7	161.3	1.6	112.8	M379 C380	M379-R383 WeakPolarHBondContact O-CB 3.47Å; M379-R383 PolarHBondContact O-N 3.12Å; C380-R383 PolarHBondContact O-N 3.21Å
384	G	51.2	Low	55.1	Low	69 Å²	69	106.8 Å²	106.8	71%	0.711	61%	0.608	S	S	*	*	H	α-helix	trans	-74.9	-19.2	168.4	0	0	0	0	0	114.8	C380 Q381 R382	C380-G384 PolarHBondContact O-N 3.48Å; Q381-G384 PolarHBondContact O-N 3.19Å; R382-G384 VanDerWaalsContact C-N 3.27Å; R382-G384 PolarHBondContact O-N 3.19Å
385	R	49.6	Very low	53.2	Low	220 Å²	220	106.8 Å²	106.8	83%	0.83	62%	0.623	S	S	*	*	H	α-helix	trans	-95.4	-8.5	177.4	-114.5	179	176.6	176.2	-2.1	114.3	Q381 R382 G387	Q381-R385 PolarHBondContact O-N 3.49Å; R382-R385 PolarHBondContact O-N 2.88Å; R385-G387 PolarHBondContact O-N 3.36Å
386	G	49	Very low	51.4	Low	65 Å²	65	108.4 Å²	108.4	67%	0.67	64%	0.641	S	S	*	*	T	Hydrogen-bonded Turn	trans	-70.8	11.1	-179.7	0	0	0	0	0	116.3	R382	R382-G386 PolarHBondContact O-N 3.3Å
387	G	47.2	Very low	49.5	Very low	76 Å²	76	113 Å²	113	78%	0.784	68%	0.675	S	S	*	*	T	Hydrogen-bonded Turn	trans	-88.4	-9.7	176.8	0	0	0	0	0	114.8	R385	R385-G387 PolarHBondContact O-N 3.36Å
388	V	49.6	Very low	47.6	Very low	128 Å²	128	118.5 Å²	118.5	78%	0.776	71%	0.713	S	S	*	*	S	Bend	trans	-133.5	102.9	171.5	-176.7	0	0	0	0	107.4
389	G	38.7	Very low	46.3	Very low	65 Å²	65	121.3 Å²	121.3	67%	0.67	74%	0.735	S	S	*	*	P	Polyproline II helix	trans	-76.7	130.7	177.2	0	0	0	0	0	111.1
390	P	44	Very low	45.2	Very low	123 Å²	123	122.5 Å²	122.5	80%	0.799	75%	0.75	S	S	*	*	P	Polyproline II helix	trans	-62.6	137.3	159.6	-14.1	29	0	0	0	108.8	L392	P390-L392 PolarHBondContact O-N 3.41Å
391	V	42.4	Very low	44.2	Very low	132 Å²	132	125.6 Å²	125.6	80%	0.8	77%	0.77	S	S	*	*	P	Polyproline II helix	trans	-59.4	131.4	172.9	175.4	0	0	0	0	109.2	V393	V391-V393 VanDerWaalsContact C-N 3.31Å; V391-V393 PolarHBondContact O-N 3.47Å
392	L	42	Very low	43.2	Very low	172 Å²	172	128.2 Å²	128.2	90%	0.901	78%	0.782	S	S	*	*			trans	-71.1	84.5	175.4	-91.9	153	0	0	0	110.3	P390 A394	P390-L392 PolarHBondContact O-N 3.41Å; L392-A394 PolarHBondContact O-N 2.88Å
393	V	41.3	Very low	42.3	Very low	129 Å²	129	130 Å²	130	78%	0.782	79%	0.789	S	S	*	*			trans	-71.9	115.3	161.1	-178.4	0	0	0	0	107.4	V391	V391-V393 VanDerWaalsContact C-N 3.31Å; V391-V393 PolarHBondContact O-N 3.47Å
394	A	37.6	Very low	41.6	Very low	80 Å²	80	123.6 Å²	123.6	66%	0.661	79%	0.785	S	S	*	*	P	Polyproline II helix	trans	-68.3	140.3	178.9	0	0	0	0	0	111	L392	L392-A394 PolarHBondContact O-N 2.88Å
395	P	40.4	Very low	40.9	Very low	115 Å²	115	124.8 Å²	124.8	75%	0.747	79%	0.788	S	S	*	*	P	Polyproline II helix	trans	-70.5	142.8	171.2	30.5	-33.8	0	0	0	110.2
396	P	41	Very low	40.2	Very low	119 Å²	119	126.2 Å²	126.2	77%	0.773	79%	0.794	S	S	*	*	P	Polyproline II helix	trans	-63.9	146.7	172	27.8	-34.1	0	0	0	110.9	C398	P396-C398 PolarHBondContact O-N 3.26Å
397	S	34.5	Very low	39.6	Very low	120 Å²	120	128.7 Å²	128.7	84%	0.839	80%	0.798	S	S	*	*	P	Polyproline II helix	trans	-65.2	123	-176	51.9	0	0	0	0	112.8	A399	S397-A399 PolarHBondContact O-N 2.75Å
398	C	36.3	Very low	38.9	Very low	129 Å²	129	133.8 Å²	133.8	87%	0.872	80%	0.801	S	S	*	*	P	Polyproline II helix	trans	-69.2	128	171.6	-63.7	0	0	0	0	111.5	P396	P396-C398 PolarHBondContact O-N 3.26Å
399	A	42.8	Very low	38	Very low	81 Å²	81	133.5 Å²	133.5	67%	0.669	81%	0.805	S	S	*	*	P	Polyproline II helix	trans	-73.1	152.2	167.5	0	0	0	0	0	111.6	S397 C401	S397-A399 PolarHBondContact O-N 2.75Å; A399-C401 PolarHBondContact O-N 3.2Å; A399-C401 VanDerWaalsContact O-N 3.14Å
400	P	37.6	Very low	37.7	Very low	120 Å²	120	141.2 Å²	141.2	78%	0.779	81%	0.814	S	S	*	*			trans	-80	95.1	-176	31.5	-35	0	0	0	112.7	H402	P400-H402 PolarHBondContact O-N 3.49Å; P400-H402 VanDerWaalsContact O-N 3.11Å
401	C	35.8	Very low	37.2	Very low	124 Å²	124	142.6 Å²	142.6	84%	0.838	82%	0.82	S	S	*	*			trans	-73.6	98.2	169.3	-72.1	0	0	0	0	111.4	A399 R403	A399-C401 PolarHBondContact O-N 3.2Å; A399-C401 VanDerWaalsContact O-N 3.14Å; C401-R403 PolarHBondContact O-N 3.3Å
402	H	39.8	Very low	36.7	Very low	190 Å²	190	140 Å²	140	88%	0.88	82%	0.821	S	S	*	*			trans	-56.5	124.1	160.7	-87.6	-104.3	0	0	0	109.7	P400	P400-H402 PolarHBondContact O-N 3.49Å; P400-H402 VanDerWaalsContact O-N 3.11Å
403	R	36.3	Very low	36	Very low	244 Å²	244	137.3 Å²	137.3	92%	0.921	82%	0.816	S	S	*	*			trans	-114.5	110.7	169.9	-157.7	174.5	-161.4	172.1	6.7	109.2	C401	C401-R403 PolarHBondContact O-N 3.3Å
404	A	37.3	Very low	35.5	Very low	94 Å²	94	142.7 Å²	142.7	78%	0.777	82%	0.822	S	S	*	*	P	Polyproline II helix	trans	-63.7	154.4	178.1	0	0	0	0	0	111.7
405	A	36	Very low	35.7	Very low	95 Å²	95	143.9 Å²	143.9	79%	0.785	82%	0.823	S	S	*	*	P	Polyproline II helix	trans	-71.6	158	173.3	0	0	0	0	0	111.6
406	W	34.3	Very low	35.1	Very low	249 Å²	249	145.6 Å²	145.6	94%	0.943	83%	0.826	S	S	*	*	P	Polyproline II helix	trans	-65.6	134	178.4	-64.9	85.4	0	0	0	112
407	P	36.5	Very low	34.6	Very low	118 Å²	118	151.6 Å²	151.6	77%	0.766	83%	0.833	S	S	*	*	P	Polyproline II helix	trans	-84.9	131.6	161.5	32.7	-30	0	0	0	110.5
408	E	33.3	Very low	34.3	Very low	182 Å²	182	153.9 Å²	153.9	85%	0.85	83%	0.83	S	S	*	*	P	Polyproline II helix	trans	-76	136.2	171.1	-70.8	-171.7	110.2	0	0	111.5	R410	E408-R410 PolarHBondContact O-N 3.11Å
409	S	31	Very low	34.1	Very low	122 Å²	122	154.3 Å²	154.3	85%	0.853	83%	0.829	S	S	*	*			trans	-83.7	104.2	175.1	56.6	0	0	0	0	111.5
410	R	32	Very low	33.4	Very low	228 Å²	228	156.6 Å²	156.6	86%	0.86	83%	0.829	S	S	*	*			trans	-132.4	117.4	162.1	-73.4	-167.6	177.2	-162.5	-0.5	111.9	E408	E408-R410 PolarHBondContact O-N 3.11Å
411	T	32.9	Very low	32.9	Very low	152 Å²	152	160.2 Å²	160.2	93%	0.933	83%	0.833	S	S	*	*			trans	-73.1	122.8	169.6	46.6	0	0	0	0	110.7
412	G	31.6	Very low	32.4	Very low	78 Å²	78	159 Å²	159	80%	0.804	83%	0.826	S	S	*	*			trans	-158.6	138.6	173.6	0	0	0	0	0	110.6
413	S	28.4	Very low	31.9	Very low	115 Å²	115	153.8 Å²	153.8	80%	0.804	82%	0.815	S	S	*	*			trans	-117.3	115.7	-157.6	55.2	0	0	0	0	115.4
414	R	29.4	Very low	31.5	Very low	242 Å²	242	152.8 Å²	152.8	91%	0.913	81%	0.812	S	S	*	*			trans	62.9	167.2	154.8	-80.7	-175.2	170.2	-175.3	-2.6	117.7
415	P	43.1	Very low	31.1	Very low	105 Å²	105	156.7 Å²	156.7	68%	0.682	81%	0.813	S	S	*	*			cis	-135.6	171	-36.3	37	-21	0	0	0	114.7
416	N	27.3	Very low	30.7	Very low	150 Å²	150	156 Å²	156	80%	0.802	81%	0.807	S	S	*	*			trans	39.9	122.3	151.5	-71.2	6.9	0	0	0	122.2
417	R	29.5	Very low	30.4	Very low	246 Å²	246	148.6 Å²	148.6	93%	0.928	79%	0.794	S	S	*	*				-158.3	164.5	113.3	-110.7	173.5	-175.8	-160.9	0.1	112.4
418	H	28.8	Very low	30	Very low	167 Å²	167	151.6 Å²	151.6	77%	0.773	80%	0.795	S	S	*	*			trans	-83.1	159.2	-174.6	-60.7	-114.9	0	0	0	113
419	V	32.6	Very low	30	Very low	139 Å²	139	148 Å²	148	84%	0.842	79%	0.785	S	S	*	*				-177.7	158.5	117	148	0	0	0	0	109.9
420	L	27.6	Very low	30	Very low	129 Å²	129	148.9 Å²	148.9	68%	0.675	78%	0.78	S	S	*	*			trans	-105.8	178.2	-174.7	-80.1	72.9	0	0	0	112.8
421	F	27.3	Very low	30	Very low	196 Å²	196	145 Å²	145	86%	0.86	78%	0.775	S	S	*	*			trans	74.4	153.4	166.9	-67	-96.2	0	0	0	117.2
422	S	26.5	Very low	29.9	Very low	99 Å²	99	145.5 Å²	145.5	69%	0.692	77%	0.771	S	S	*	*			cis	-169.9	179.1	-30	-166.6	0	0	0	0	110.1
423	A	28.9	Very low	29.7	Very low	79 Å²	79	147 Å²	147	65%	0.653	77%	0.769	S	S	*	*			trans	23.5	116.6	158	0	0	0	0	0	119.4
424	R	27.2	Very low	30	Very low	224 Å²	224	148 Å²	148	85%	0.845	77%	0.771	S	S	*	*				67.1	143.8	77.6	-86.7	-167.8	171.6	-177.4	-0.5	115.5
425	H	28.5	Very low	30.4	Very low	175 Å²	175	144.9 Å²	144.9	81%	0.81	77%	0.766	S	S	*	*			trans	75.9	152.1	176.3	-58.8	-83.8	0	0	0	116.1
426	A	28	Very low	30.5	Very low	80 Å²	80	144.8 Å²	144.8	66%	0.661	77%	0.766	S	S	*	*			cis	-172.3	171.9	-28.7	0	0	0	0	0	110.3
427	S	27.4	Very low	30.8	Very low	95 Å²	95	145.6 Å²	145.6	66%	0.664	77%	0.768	S	S	*	*			trans	78.5	129	137.8	176	0	0	0	0	120.9
428	K	29.9	Very low	31.1	Very low	180 Å²	180	139.8 Å²	139.8	78%	0.783	76%	0.76	S	S	*	*			trans	77.4	120.3	149.6	-75.7	175.1	-173.8	-178.1	0	117.5
429	T	32.7	Very low	31.5	Very low	106 Å²	106	136.5 Å²	136.5	65%	0.65	76%	0.762	S	S	*	*				65.2	136.5	71.7	68.1	0	0	0	0	112.8
430	D	30.1	Very low	31.6	Very low	141 Å²	141	136.3 Å²	136.3	75%	0.754	76%	0.761	S	S	*	*			cis	-164.8	-160.6	-0.3	-108.8	-30.1	0	0	0	108.6
431	I	33.3	Very low	32.3	Very low	146 Å²	146	139 Å²	139	75%	0.749	79%	0.79	S	S	*	*			trans	87.5	93.7	153.9	-49.4	-172.2	0	0	0	117.8
432	L	29.6	Very low	32.6	Very low	163 Å²	163	136.1 Å²	136.1	85%	0.853	79%	0.786	S	S	*	*				47.9	148.1	122.8	-69.8	160.5	0	0	0	123.5
433	S	28.7	Very low	32.9	Very low	109 Å²	109	138.1 Å²	138.1	76%	0.762	79%	0.791	S	S	*	*			trans	78.7	112.9	152	-161.5	0	0	0	0	119.2
434	V	33	Very low	33.1	Very low	137 Å²	137	141.3 Å²	141.3	83%	0.83	80%	0.799	S	S	*	*				-167	143.2	105.9	147.2	0	0	0	0	108.2
435	E	38.3	Very low	33.5	Very low	176 Å²	176	136.5 Å²	136.5	82%	0.822	80%	0.796	S	S	*	*			trans	-113.3	-169.4	176.6	-135.3	-161.7	-174.4	0	0	111.2
436	P	44.8	Very low	33.8	Very low	104 Å²	104	134.1 Å²	134.1	68%	0.675	80%	0.796	S	S	*	*			trans	-88.1	163.4	-131.3	40.2	-35	0	0	0	115.1
437	I	33.3	Very low	34.2	Very low	166 Å²	166	137.7 Å²	137.7	85%	0.851	80%	0.804	S	S	*	*			trans	-104.9	126.8	164.7	-67.7	176.8	0	0	0	109.6
438	V	37.6	Very low	34.7	Very low	124 Å²	124	140.7 Å²	140.7	75%	0.752	82%	0.815	S	S	*	*			trans	-91.6	140.3	165.6	175.2	0	0	0	0	108.6	V440	V438-V440 HydrophobicContact CG1-CG2 4.31Å
439	A	36.4	Very low	35	Very low	98 Å²	98	137.7 Å²	137.7	81%	0.81	82%	0.817	S	S	*	*			trans	-133.5	138.7	164.1	0	0	0	0	0	109.3
440	V	35.1	Very low	35.2	Very low	136 Å²	136	140.3 Å²	140.3	82%	0.824	83%	0.831	S	S	*	*			trans	-114.1	134.2	-177.3	173.5	0	0	0	0	109.3	V438	V438-V440 HydrophobicContact CG1-CG2 4.31Å
441	S	42.3	Very low	35.7	Very low	184 Å²	184	140.3 Å²	140.3	100%	1.287	84%	0.838	S	S	*	*			trans	-160.8	0	142.1	-171.5	0	0	0	0	110.4

Retrieved 441 of 441 residues in 2620.2 ms (Link to these results)

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