A0A060XET2_ONCMY Loading...

Glycine N-methyltransferase

AlphaFold DB , UniProt , Accession A0A060XET2, Species ONCMY (Oncorhynchus mykiss, Rainbow trout), Gene gnmt, Length 294 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M34.4Very low40.9Very low243 Ų243117.1 Ų117.1100%1.19762%0.62SS**  0109.60-78.6-176.9-101.200106.9
2S31.1Very low41.2Very low70 Ų70118.4 Ų118.449%0.4963%0.626SS.*  trans-67.9132.4-174.6147.30000110D4 S5S2-D4 PolarHBondContact O-N 3.16Å; S2-D4 VanDerWaalsContact O-N 3.16Å; S2-D4 VanDerWaalsContact OG-CB 3.26Å; S2-D4 WeakPolarHBondContact OG-CB 3.46Å; S2-D4 PolarHBondContact OG-N 2.89Å; S2-D4 PolarHBondContact OG-OD2 3Å; S2-S5 PolarHBondContact O-OG 3.01Å
3V34.4Very low41.7Very low113 Ų113112 Ų11269%0.68561%0.606SS**G310 helixtrans-69.4-2.3177.2-166.10000111.2
4D37.2Very low41.5Very low146 Ų146114.6 Ų114.678%0.78163%0.627SS**G310 helixtrans-91.58.4-176.4-49.5-56.2000114.1S2S2-D4 PolarHBondContact O-N 3.16Å; S2-D4 VanDerWaalsContact O-N 3.16Å; S2-D4 VanDerWaalsContact OG-CB 3.26Å; S2-D4 WeakPolarHBondContact OG-CB 3.46Å; S2-D4 PolarHBondContact OG-N 2.89Å; S2-D4 PolarHBondContact OG-OD2 3Å
5S36.3Very low41.9Very low107 Ų107109.7 Ų109.775%0.74861%0.608SS**G310 helixtrans-91.65.5179.550.90000114.5S2S2-S5 PolarHBondContact O-OG 3.01Å
6V41.5Very low42.4Very low91 Ų91105.1 Ų105.155%0.55259%0.586SS**SBendtrans-100.8116177.5-175.40000109.9R8V6-R8 HydrophobicContact CB-CG 4.43Å; V6-R8 HydrophobicContact CG1-CG 3.98Å; V6-R8 PolarHBondContact O-N 3.48Å
7F43.5Very low43Very low179 Ų179106.4 Ų106.479%0.78560%0.596SS**  trans-63.7102167.9-124.8-86.9000108.5
8R48.4Very low43.7Very low110 Ų110102.8 Ų102.842%0.41559%0.587SS.*  trans-99135.8173.6-64.7-176.3-179.4175.10.3109V6 R10 R241V6-R8 HydrophobicContact CB-CG 4.43Å; V6-R8 HydrophobicContact CG1-CG 3.98Å; V6-R8 PolarHBondContact O-N 3.48Å; R8-R10 WeakPolarHBondContact CB-O 3.33Å; R8-R10 PolarHBondContact O-N 3.2Å; R8-R241 PolarHBondContact O-NH1 3.21Å
9T47.9Very low44.5Very low80 Ų8098.6 Ų98.649%0.49156%0.562SS.*SBendtrans-68.7-10.5174.248.10000113S243T9-S243 PolarHBondContact O-OG 3.19Å
10R48.7Very low45.6Very low114 Ų11495.2 Ų95.243%0.4354%0.544SS..SBendtrans-163.4164.7-176.962.3-179.1-174.5-169.22.4113.9R8R8-R10 WeakPolarHBondContact CB-O 3.33Å; R8-R10 PolarHBondContact O-N 3.2Å
11S46.7Very low47Very low35 Ų3591.7 Ų91.725%0.24552%0.524CS..  trans-69.5155.3164.9-710000112.1D25S11-D25 WeakPolarHBondContact CB-OD2 3.14Å; S11-D25 PolarHBondContact OG-OD2 2.86Å
12L44.8Very low49.2Very low133 Ų13381.1 Ų81.170%0.69647%0.472SS*.  trans-83.9120177.3-72.7174.9000110.5
13G47.5Very low51.3Low35 Ų3579.2 Ų79.236%0.36145%0.454SS..  trans-156.5141.6173.200000110.5
14V39.3Very low53.1Low149 Ų14975.2 Ų75.290%0.90343%0.433SS*.  trans-88128.8170.8-175.10000107
15A46.7Very low54.7Low41 Ų4171 Ų7134%0.33941%0.41SS..  trans-105169.5-174.400000114L19 D21A15-L19 WeakPolarHBondContact CB-O 3.17Å; A15-D21 HydrophobicContact CB-CB 4.48Å
16S50.6Low56.3Low36 Ų3667 Ų6725%0.25239%0.385SS..SBendtrans-59.6152.8151.359.50000110.2G18 L19 N118S16-G18 PolarHBondContact O-N 2.86Å; S16-L19 PolarHBondContact O-N 2.83Å; S16-N118 PolarHBondContact OG-ND2 2.74Å
17V52.7Low57.9Low126 Ų12668.5 Ų68.576%0.76439%0.385SS*.THydrogen-bonded Turntrans-48.3122.9-167.8-178.20000112.1L19 N118V17-L19 VanDerWaalsContact C-N 3.34Å; V17-L19 PolarHBondContact O-N 3.29Å; V17-N118 PolarHBondContact O-ND2 2.82Å
18G54.2Low59.3Low42 Ų4260 Ų6043%0.43335%0.348SS..THydrogen-bonded Turntrans81.1-13.8169.100000117.7S16 P20S16-G18 PolarHBondContact O-N 2.86Å; G18-P20 WeakPolarHBondContact O-CD 3.3Å
19L60Low60.4Low23 Ų2354.9 Ų54.912%0.1233%0.329CS..SBendtrans-119.590.8-179.4-168.6120.6000111.6A15 S16 V17 D21 A88 N118 W119 L146A15-L19 WeakPolarHBondContact CB-O 3.17Å; S16-L19 PolarHBondContact O-N 2.83Å; V17-L19 VanDerWaalsContact C-N 3.34Å; V17-L19 PolarHBondContact O-N 3.29Å; L19-D21 PolarHBondContact O-N 3.4Å; L19-A88 HydrophobicContact CD2-CB 3.81Å; L19-N118 VanDerWaalsContact CB-ND2 3.34Å; L19-N118 WeakPolarHBondContact CB-ND2 3.29Å; L19-W119 HydrophobicContact CD1-CE3 4.18Å; L19-W119 HydrophobicContact CD1-CZ3 4.43Å; L19-L146 HydrophobicContact CD1-CB 4.26Å; L19-L146 HydrophobicContact CD1-CD1 3.71Å; L19-L146 HydrophobicContact CD1-CG 4.48Å
20P67.1Low61.6Low31 Ų3158.7 Ų58.720%0.20134%0.339CS..  trans-52.5122.5179.8-24.633.4000112.6G18 Q22 F149G18-P20 WeakPolarHBondContact O-CD 3.3Å; P20-Q22 PolarHBondContact O-N 3.12Å; P20-Q22 VanDerWaalsContact O-N 3.1Å; P20-F149 HydrophobicContact CG-CE2 3.76Å; P20-F149 HydrophobicContact CG-CZ 3.95Å
21D74.6Confident62.7Low21 Ų2153.7 Ų53.711%0.11232%0.321CS..  trans-76101.2179.1-177.68.7000110.1A15 L19 Y23 A24 S89A15-D21 HydrophobicContact CB-CB 4.48Å; L19-D21 PolarHBondContact O-N 3.4Å; D21-Y23 PolarHBondContact O-N 2.89Å; D21-Y23 WeakPolarHBondContact OD1-CA 3.45Å; D21-Y23 VanDerWaalsContact OD1-CB 3.3Å; D21-Y23 WeakPolarHBondContact OD1-CB 3.45Å; D21-Y23 PolarHBondContact OD1-N 3.33Å; D21-A24 HydrophobicContact CB-CB 4.05Å; D21-A24 WeakPolarHBondContact O-CB 3.36Å; D21-A24 PolarHBondContact O-N 3.24Å; D21-A24 PolarHBondContact OD1-N 3.17Å; D21-A24 PolarHBondContact OD2-N 3.5Å; D21-S89 PolarHBondContact OD1-OG 3.43Å; D21-S89 PolarHBondContact OD2-OG 2.8Å
22Q79.3Confident63.8Low22 Ų2252.8 Ų52.810%0.10331%0.312CS..THydrogen-bonded Turntrans-69.1-12.9176.2-61.7-168.863.800112.7P20 H145 L242 S243P20-Q22 PolarHBondContact O-N 3.12Å; P20-Q22 VanDerWaalsContact O-N 3.1Å; Q22-H145 PolarHBondContact NE2-ND1 3.01Å; Q22-H145 VanDerWaalsContact NE2-ND1 3.16Å; Q22-L242 HydrophobicContact CB-CD2 4.2Å; Q22-S243 PolarHBondContact NE2-O 3.24Å; Q22-S243 PolarHBondContact OE1-O 3.38Å
23Y76.1Confident64.9Low29 Ų2951.6 Ų51.611%0.11430%0.303CS..THydrogen-bonded Turntrans-99.9-0.5179.2-51.4-82.1000113.1D21 D25 G26 A28 M92 H145 L242D21-Y23 PolarHBondContact O-N 2.89Å; D21-Y23 WeakPolarHBondContact OD1-CA 3.45Å; D21-Y23 VanDerWaalsContact OD1-CB 3.3Å; D21-Y23 WeakPolarHBondContact OD1-CB 3.45Å; D21-Y23 PolarHBondContact OD1-N 3.33Å; Y23-D25 PolarHBondContact O-N 3.23Å; Y23-D25 VanDerWaalsContact O-N 3.14Å; Y23-G26 WeakPolarHBondContact O-CA 3.27Å; Y23-G26 PolarHBondContact O-N 3.32Å; Y23-A28 HydrophobicContact CD1-CB 3.74Å; Y23-A28 HydrophobicContact CE1-CB 4.27Å; Y23-M92 HydrophobicContact CD1-CG 4.4Å; Y23-M92 HydrophobicContact CD1-SD 4.07Å; Y23-M92 HydrophobicContact CD2-CG 4.36Å; Y23-M92 HydrophobicContact CE1-CE 4.36Å; Y23-M92 HydrophobicContact CE1-SD 4.45Å; Y23-M92 HydrophobicContact CG-CG 4.1Å; Y23-M92 HydrophobicContact CG-SD 4.36Å; Y23-H145 PolarHBondContact OH-CE1 2.99Å; Y23-H145 VanDerWaalsContact OH-CE1 3.29Å; Y23-H145 PolarHBondContact OH-NE2 3.09Å; Y23-L242 HydrophobicContact CE1-CD1 4.49Å; Y23-L242 HydrophobicContact CE1-CD2 4.05Å
24A72.8Confident65.8Low29 Ų2952.8 Ų52.824%0.2430%0.3CS..THydrogen-bonded Turntrans-59.4-27.7-176.200000113.7D21 G26D21-A24 HydrophobicContact CB-CB 4.05Å; D21-A24 WeakPolarHBondContact O-CB 3.36Å; D21-A24 PolarHBondContact O-N 3.24Å; D21-A24 PolarHBondContact OD1-N 3.17Å; D21-A24 PolarHBondContact OD2-N 3.5Å; A24-G26 PolarHBondContact O-N 3.42Å
25D71.3Confident67Low58 Ų5845.8 Ų45.831%0.3126%0.258SS..THydrogen-bonded Turntrans-71.4-8.6175.673.114.3000113.3S11 Y23 K27S11-D25 WeakPolarHBondContact CB-OD2 3.14Å; S11-D25 PolarHBondContact OG-OD2 2.86Å; Y23-D25 PolarHBondContact O-N 3.23Å; Y23-D25 VanDerWaalsContact O-N 3.14Å; D25-K27 PolarHBondContact O-N 3.2Å; D25-K27 WeakPolarHBondContact OD1-CB 3.28Å; D25-K27 PolarHBondContact OD1-N 2.93Å
26G68.9Low67.8Low22 Ų2244 Ų4423%0.22724%0.242CC..SBendtrans65.9-3.917900000114.7Y23 A24 K30Y23-G26 WeakPolarHBondContact O-CA 3.27Å; Y23-G26 PolarHBondContact O-N 3.32Å; A24-G26 PolarHBondContact O-N 3.42Å; G26-K30 VanDerWaalsContact O-CB 3.31Å; G26-K30 WeakPolarHBondContact O-CB 3.22Å; G26-K30 PolarHBondContact O-N 3.38Å
27K74.6Confident68.3Low123 Ų12343.2 Ų43.254%0.53524%0.241SC..Hα-helixtrans-68.4-53-178-68.9-177.9178-179.90109.7D25 A29 K30 V31D25-K27 PolarHBondContact O-N 3.2Å; D25-K27 WeakPolarHBondContact OD1-CB 3.28Å; D25-K27 PolarHBondContact OD1-N 2.93Å; K27-A29 VanDerWaalsContact C-N 3.33Å; K27-A29 PolarHBondContact O-N 3.02Å; K27-K30 PolarHBondContact O-N 3.18Å; K27-V31 WeakPolarHBondContact O-CG2 3.35Å; K27-V31 PolarHBondContact O-N 2.87Å; K27-V31 VanDerWaalsContact O-N 3.1Å
28A72.6Confident69Low2 Ų241.8 Ų41.82%0.01723%0.228CC..Hα-helixtrans-56.1-49.1175.800000110.2Y23 K30 V31 W32 F240Y23-A28 HydrophobicContact CD1-CB 3.74Å; Y23-A28 HydrophobicContact CE1-CB 4.27Å; A28-K30 PolarHBondContact O-N 3.05Å; A28-V31 CarbonylContact O-C 3.54Å; A28-V31 PolarHBondContact O-N 2.89Å; A28-W32 WeakPolarHBondContact O-CA 3.29Å; A28-W32 WeakPolarHBondContact O-CB 3.42Å; A28-W32 PolarHBondContact O-N 3.4Å; A28-F240 HydrophobicContact CB-CD2 4.04Å; A28-F240 HydrophobicContact CB-CG 4.4Å
29A71.8Confident69.5Low2 Ų242.6 Ų42.62%0.01723%0.225CC..Hα-helixtrans-59.3-40.8178.800000113.4K27 W32 K91 M92 Y95K27-A29 VanDerWaalsContact C-N 3.33Å; K27-A29 PolarHBondContact O-N 3.02Å; A29-W32 PolarHBondContact O-N 2.94Å; A29-K91 HydrophobicContact CB-CB 4.19Å; A29-M92 HydrophobicContact CB-SD 3.97Å; A29-Y95 HydrophobicContact CB-CE2 4.09Å; A29-Y95 PolarHBondContact O-OH 3.28Å
30K73.1Confident69.9Low160 Ų16050.3 Ų50.370%0.69625%0.253SS*.Hα-helixtrans-64.6-41.9178.2-174.8-177.5178-1710112.3G26 K27 A28G26-K30 VanDerWaalsContact O-CB 3.31Å; G26-K30 WeakPolarHBondContact O-CB 3.22Å; G26-K30 PolarHBondContact O-N 3.38Å; K27-K30 PolarHBondContact O-N 3.18Å; A28-K30 PolarHBondContact O-N 3.05Å
31V71.5Confident70Confident8 Ų850.5 Ų50.55%0.04826%0.255CS..Hα-helixtrans-92-4.9-179.4-550000112.9K27 A28 Q33 L34 Y35 F240K27-V31 WeakPolarHBondContact O-CG2 3.35Å; K27-V31 PolarHBondContact O-N 2.87Å; K27-V31 VanDerWaalsContact O-N 3.1Å; A28-V31 CarbonylContact O-C 3.54Å; A28-V31 PolarHBondContact O-N 2.89Å; V31-Q33 VanDerWaalsContact C-N 3.26Å; V31-Q33 PolarHBondContact O-N 3.3Å; V31-L34 CarbonylContact O-C 3.59Å; V31-L34 WeakPolarHBondContact O-CA 3.47Å; V31-L34 WeakPolarHBondContact O-CB 3.33Å; V31-L34 PolarHBondContact O-N 3.34Å; V31-Y35 PolarHBondContact O-N 2.86Å; V31-F240 HydrophobicContact CG2-CD1 3.5Å; V31-F240 VanDerWaalsContact CG2-CD1 3.5Å; V31-F240 HydrophobicContact CG2-CE1 3.49Å; V31-F240 VanDerWaalsContact CG2-CE1 3.49Å; V31-F240 HydrophobicContact CG2-CG 4.38Å; V31-F240 HydrophobicContact CG2-CZ 4.38Å
32W69.5Low69.9Low16 Ų1650 Ų506%0.06125%0.251CS..Hα-helixtrans-59.8-39-175.6-162.4-127.2000112A28 A29 L34 Y35 I36 M92 Y197 L242A28-W32 WeakPolarHBondContact O-CA 3.29Å; A28-W32 WeakPolarHBondContact O-CB 3.42Å; A28-W32 PolarHBondContact O-N 3.4Å; A29-W32 PolarHBondContact O-N 2.94Å; W32-L34 VanDerWaalsContact C-N 3.3Å; W32-L34 PolarHBondContact O-N 2.87Å; W32-Y35 HydrophobicContact CD2-CD1 4.37Å; W32-Y35 AromaticContact CE3-CD1 3.51Å; W32-Y35 HydrophobicContact CE3-CD1 3.51Å; W32-Y35 HydrophobicContact CE3-CE1 4.31Å; W32-Y35 HydrophobicContact CE3-CG 4.19Å; W32-Y35 AromaticContact CH2-CD1 3.71Å; W32-Y35 HydrophobicContact CH2-CD1 3.71Å; W32-Y35 AromaticContact CH2-CE1 3.73Å; W32-Y35 HydrophobicContact CH2-CE1 3.73Å; W32-Y35 AromaticContact CZ3-CD1 3.1Å; W32-Y35 HydrophobicContact CZ3-CD1 3.1Å; W32-Y35 AromaticContact CZ3-CE1 3.46Å; W32-Y35 HydrophobicContact CZ3-CE1 3.46Å; W32-Y35 VanDerWaalsContact CZ3-CE1 3.46Å; W32-Y35 HydrophobicContact CZ3-CG 4.08Å; W32-Y35 PolarHBondContact O-N 2.78Å; W32-I36 HydrophobicContact CD2-CD1 4.28Å; W32-I36 HydrophobicContact CD2-CG1 4.33Å; W32-I36 HydrophobicContact CG-CD1 3.94Å; W32-I36 HydrophobicContact CG-CG1 4.4Å; W32-I36 VanDerWaalsContact NE1-CD1 3.29Å; W32-I36 WeakPolarHBondContact O-CB 3.33Å; W32-I36 VanDerWaalsContact O-CG1 3.31Å; W32-I36 WeakPolarHBondContact O-CG1 3.49Å; W32-I36 PolarHBondContact O-N 2.9Å; W32-M92 HydrophobicContact CG-CE 4.17Å; W32-Y197 HydrophobicContact CH2-CD1 4.37Å; W32-Y197 AromaticContact CH2-CE1 3.39Å; W32-Y197 HydrophobicContact CH2-CE1 3.39Å; W32-Y197 AromaticContact CH2-CZ 3.6Å; W32-Y197 WeakPolarHBondContact CH2-OH 3.12Å; W32-Y197 AromaticContact CZ2-CE1 3.39Å; W32-Y197 HydrophobicContact CZ2-CE1 3.39Å; W32-Y197 AromaticContact CZ2-CZ 3.69Å; W32-Y197 VanDerWaalsContact CZ2-OH 3.22Å; W32-Y197 WeakPolarHBondContact CZ2-OH 3.39Å; W32-Y197 HydrophobicContact CZ3-CE1 4.19Å; W32-L242 HydrophobicContact CZ3-CD1 4.45Å
33Q67.9Low69.8Low109 Ų10949.8 Ų49.851%0.50925%0.251SS..Hα-helixtrans-62.4-37.3174.3-66.7-175-2900112V31 G37V31-Q33 VanDerWaalsContact C-N 3.26Å; V31-Q33 PolarHBondContact O-N 3.3Å; Q33-G37 PolarHBondContact O-N 2.89Å; Q33-G37 VanDerWaalsContact O-N 3.12Å
34L67.1Low70Confident59 Ų5955.1 Ų55.131%0.30928%0.278SS..Hα-helixtrans-71.8-35.1175.2-61.3173.4000112V31 W32 G37 S199 L201 V227V31-L34 CarbonylContact O-C 3.59Å; V31-L34 WeakPolarHBondContact O-CA 3.47Å; V31-L34 WeakPolarHBondContact O-CB 3.33Å; V31-L34 PolarHBondContact O-N 3.34Å; W32-L34 VanDerWaalsContact C-N 3.3Å; W32-L34 PolarHBondContact O-N 2.87Å; L34-G37 PolarHBondContact O-N 2.99Å; L34-S199 WeakPolarHBondContact O-CB 3.18Å; L34-S199 PolarHBondContact O-OG 3.25Å; L34-L201 HydrophobicContact CB-CD1 4.01Å; L34-V227 HydrophobicContact CD1-CB 4.37Å; L34-V227 HydrophobicContact CD1-CG1 3.92Å; L34-V227 HydrophobicContact CD1-CG2 4Å
35Y64.7Low70.3Confident3 Ų357 Ų571%0.01228%0.281CS..Hα-helixtrans-73.3-43.9179.5177.4-105.9000112.7V31 W32 G37 Y197 S199 Y223 V225 F240V31-Y35 PolarHBondContact O-N 2.86Å; W32-Y35 HydrophobicContact CD2-CD1 4.37Å; W32-Y35 AromaticContact CE3-CD1 3.51Å; W32-Y35 HydrophobicContact CE3-CD1 3.51Å; W32-Y35 HydrophobicContact CE3-CE1 4.31Å; W32-Y35 HydrophobicContact CE3-CG 4.19Å; W32-Y35 AromaticContact CH2-CD1 3.71Å; W32-Y35 HydrophobicContact CH2-CD1 3.71Å; W32-Y35 AromaticContact CH2-CE1 3.73Å; W32-Y35 HydrophobicContact CH2-CE1 3.73Å; W32-Y35 AromaticContact CZ3-CD1 3.1Å; W32-Y35 HydrophobicContact CZ3-CD1 3.1Å; W32-Y35 AromaticContact CZ3-CE1 3.46Å; W32-Y35 HydrophobicContact CZ3-CE1 3.46Å; W32-Y35 VanDerWaalsContact CZ3-CE1 3.46Å; W32-Y35 HydrophobicContact CZ3-CG 4.08Å; W32-Y35 PolarHBondContact O-N 2.78Å; Y35-G37 PolarHBondContact O-N 2.87Å; Y35-Y197 AromaticContact CD1-CD1 3.36Å; Y35-Y197 HydrophobicContact CD1-CD1 3.36Å; Y35-Y197 AromaticContact CD1-CE1 3.73Å; Y35-Y197 HydrophobicContact CD1-CE1 3.73Å; Y35-Y197 HydrophobicContact CD1-CG 4.07Å; Y35-Y197 AromaticContact CE1-CD1 3.08Å; Y35-Y197 HydrophobicContact CE1-CD1 3.08Å; Y35-Y197 AromaticContact CE1-CD2 3.97Å; Y35-Y197 HydrophobicContact CE1-CD2 3.97Å; Y35-Y197 AromaticContact CE1-CE1 3.45Å; Y35-Y197 HydrophobicContact CE1-CE1 3.45Å; Y35-Y197 VanDerWaalsContact CE1-CE1 3.45Å; Y35-Y197 HydrophobicContact CE1-CE2 4.27Å; Y35-Y197 AromaticContact CE1-CG 3.38Å; Y35-Y197 HydrophobicContact CE1-CG 3.38Å; Y35-Y197 HydrophobicContact CG-CD1 4.46Å; Y35-Y197 AromaticContact CZ-CD1 3.98Å; Y35-Y197 AromaticContact CZ-CG 3.82Å; Y35-S199 VanDerWaalsContact O-CB 3.29Å; Y35-S199 WeakPolarHBondContact O-CB 3.11Å; Y35-Y223 HydrophobicContact CD2-CD1 4.3Å; Y35-Y223 HydrophobicContact CE1-CE1 4.47Å; Y35-Y223 AromaticContact CE2-CD1 3.56Å; Y35-Y223 HydrophobicContact CE2-CD1 3.56Å; Y35-Y223 AromaticContact CE2-CE1 3.73Å; Y35-Y223 HydrophobicContact CE2-CE1 3.73Å; Y35-Y223 AromaticContact CZ-CD1 3.91Å; Y35-Y223 AromaticContact CZ-CE1 3.58Å; Y35-Y223 VanDerWaalsContact OH-CE1 3.27Å; Y35-Y223 WeakPolarHBondContact OH-CE1 3.48Å; Y35-V225 HydrophobicContact CD2-CG2 4.24Å; Y35-F240 HydrophobicContact CD2-CZ 4.28Å; Y35-F240 HydrophobicContact CG-CZ 4.2Å
36I63.1Low71.1Confident2 Ų254.2 Ų54.21%0.0127%0.266CS..Hα-helixtrans-59.8-37.9170.8-66162.5000110.1W32 T39 R42 V71 Y197 K198W32-I36 HydrophobicContact CD2-CD1 4.28Å; W32-I36 HydrophobicContact CD2-CG1 4.33Å; W32-I36 HydrophobicContact CG-CD1 3.94Å; W32-I36 HydrophobicContact CG-CG1 4.4Å; W32-I36 VanDerWaalsContact NE1-CD1 3.29Å; W32-I36 WeakPolarHBondContact O-CB 3.33Å; W32-I36 VanDerWaalsContact O-CG1 3.31Å; W32-I36 WeakPolarHBondContact O-CG1 3.49Å; W32-I36 PolarHBondContact O-N 2.9Å; I36-T39 HydrophobicContact CG2-CG2 3.84Å; I36-R42 HydrophobicContact CG2-CB 4.46Å; I36-V71 HydrophobicContact CD1-CG2 4.07Å; I36-Y197 HydrophobicContact CB-CD1 4.47Å; I36-Y197 HydrophobicContact CG1-CD1 3.92Å; I36-Y197 HydrophobicContact CG1-CE1 3.85Å; I36-K198 PolarHBondContact O-N 3.18Å
37G62.5Low72.2Confident21 Ų2156 Ų5622%0.21627%0.268CS..  trans78.3-147.4-173.100000110.5Q33 L34 Y35 T39Q33-G37 PolarHBondContact O-N 2.89Å; Q33-G37 VanDerWaalsContact O-N 3.12Å; L34-G37 PolarHBondContact O-N 2.99Å; Y35-G37 PolarHBondContact O-N 2.87Å; G37-T39 PolarHBondContact O-N 3.21Å
38D65.9Low73.1Confident95 Ų9553.9 Ų53.951%0.50827%0.269SS..  trans-65.7108.3173.5177.120.4000110.6R40 S41 R42D38-R40 PolarHBondContact O-N 3.15Å; D38-R40 WeakPolarHBondContact OD1-CB 3.34Å; D38-R40 PolarHBondContact OD1-N 3.02Å; D38-S41 WeakPolarHBondContact O-CB 3.36Å; D38-S41 PolarHBondContact O-N 3.1Å; D38-S41 VanDerWaalsContact O-N 3.14Å; D38-S41 WeakPolarHBondContact OD2-CB 3.38Å; D38-S41 PolarHBondContact OD2-N 3.24Å; D38-R42 PolarHBondContact O-N 3.46Å
39T66.1Low74.2Confident59 Ų5956.1 Ų56.136%0.36228%0.277SS..Hα-helixtrans-60.7-25.718052.90000112.4I36 G37 T43 V71I36-T39 HydrophobicContact CG2-CG2 3.84Å; G37-T39 PolarHBondContact O-N 3.21Å; T39-T43 PolarHBondContact O-N 2.93Å; T39-T43 PolarHBondContact O-OG1 3.13Å; T39-V71 HydrophobicContact CG2-CG1 4.27Å; T39-V71 HydrophobicContact CG2-CG2 3.79Å
40R68Low75.4Confident186 Ų18656 Ų5670%0.70228%0.276SS*.Hα-helixtrans-70.7-50.4173.3-64.1-177.6-178179.81.7110.9D38 R42 T43 E44D38-R40 PolarHBondContact O-N 3.15Å; D38-R40 WeakPolarHBondContact OD1-CB 3.34Å; D38-R40 PolarHBondContact OD1-N 3.02Å; R40-R42 PolarHBondContact O-N 2.67Å; R40-T43 PolarHBondContact O-N 3Å; R40-T43 VanDerWaalsContact O-N 3.13Å; R40-T43 PolarHBondContact O-OG1 3.04Å; R40-T43 VanDerWaalsContact O-OG1 3.05Å; R40-E44 WeakPolarHBondContact O-CG 3.34Å; R40-E44 PolarHBondContact O-N 2.81Å
41S69.3Low76.6Confident35 Ų3548.9 Ų48.925%0.24525%0.246CC..Hα-helixtrans-57.4-33.8174.2177.10000113.7D38 K198D38-S41 WeakPolarHBondContact O-CB 3.36Å; D38-S41 PolarHBondContact O-N 3.1Å; D38-S41 VanDerWaalsContact O-N 3.14Å; D38-S41 WeakPolarHBondContact OD2-CB 3.38Å; D38-S41 PolarHBondContact OD2-N 3.24Å; S41-K198 PolarHBondContact O-NZ 3.03Å
42R72.8Confident77.8Confident10 Ų1051.9 Ų51.94%0.03827%0.267CS..Hα-helixtrans-60.4-58.9171168.8-174.8169.8142-14.2110.7I36 D38 R40 E44 E45 Y46 D72 Y196I36-R42 HydrophobicContact CG2-CB 4.46Å; D38-R42 PolarHBondContact O-N 3.46Å; R40-R42 PolarHBondContact O-N 2.67Å; R42-E44 VanDerWaalsContact C-N 3.29Å; R42-E44 PolarHBondContact O-N 2.93Å; R42-E45 PolarHBondContact O-N 3.38Å; R42-Y46 HydrophobicContact CG-CE1 3.81Å; R42-Y46 PolarHBondContact NE-OH 3.02Å; R42-Y46 VanDerWaalsContact NE-OH 3.09Å; R42-Y46 WeakPolarHBondContact O-CE1 3.46Å; R42-D72 IonicContact CZ-OD2 3.49Å; R42-D72 IonicContact NH2-OD2 2.68Å; R42-D72 PolarHBondContact NH2-OD2 2.99Å; R42-Y196 WeakPolarHBondContact CD-O 3.42Å; R42-Y196 WeakPolarHBondContact CG-O 3.25Å; R42-Y196 PolarHBondContact NH1-O 3.06Å
43T75.9Confident79.2Confident17 Ų1751.9 Ų51.910%0.10427%0.268CS..Hα-helixtrans-65.7-32.3-171.750.80000112T39 R40 E45 Y46 K47 V71 M75T39-T43 PolarHBondContact O-N 2.93Å; T39-T43 PolarHBondContact O-OG1 3.13Å; R40-T43 PolarHBondContact O-N 3Å; R40-T43 VanDerWaalsContact O-N 3.13Å; R40-T43 PolarHBondContact O-OG1 3.04Å; R40-T43 VanDerWaalsContact O-OG1 3.05Å; T43-E45 PolarHBondContact O-N 3.06Å; T43-Y46 PolarHBondContact O-N 3.36Å; T43-Y46 VanDerWaalsContact O-N 3.13Å; T43-K47 WeakPolarHBondContact O-CA 3.47Å; T43-K47 WeakPolarHBondContact O-CB 3.37Å; T43-K47 PolarHBondContact O-N 3.41Å; T43-V71 HydrophobicContact CG2-CG1 3.96Å; T43-M75 HydrophobicContact CG2-CB 4.14Å; T43-M75 HydrophobicContact CG2-CG 4.26Å; T43-M75 HydrophobicContact CG2-SD 3.77Å
44E80.8Confident80.6Confident142 Ų14246.7 Ų46.766%0.66424%0.244SC*.Hα-helixtrans-52.5-29.5178.2-79.3177.4179.900115R40 R42R40-E44 WeakPolarHBondContact O-CG 3.34Å; R40-E44 PolarHBondContact O-N 2.81Å; R42-E44 VanDerWaalsContact C-N 3.29Å; R42-E44 PolarHBondContact O-N 2.93Å
45E78.8Confident82.1Confident67 Ų6749.6 Ų49.631%0.31325%0.254SS..THydrogen-bonded Turntrans-73.2-31.2-178.9-83.6-172.9-177.800114.3R42 T43 K193 I195 K198R42-E45 PolarHBondContact O-N 3.38Å; T43-E45 PolarHBondContact O-N 3.06Å; E45-K193 WeakPolarHBondContact OE1-CE 3.43Å; E45-K193 IonicContact OE1-NZ 3.93Å; E45-K193 PolarHBondContact OE1-NZ 2.95Å; E45-I195 WeakPolarHBondContact OE2-CA 3.42Å; E45-K198 WeakPolarHBondContact OE1-CE 3.49Å; E45-K198 IonicContact OE1-NZ 3Å; E45-K198 PolarHBondContact OE1-NZ 3.11Å; E45-K198 WeakPolarHBondContact OE2-CE 3.35Å; E45-K198 IonicContact OE2-NZ 2.8Å
46Y88.9Confident83.6Confident0 Ų057 Ų570%029%0.289CS..THydrogen-bonded Turntrans-127.1-11.3-172.965.2-96.6000114.3R42 T43 S48 W49 V50 D72 M75 Y196 F272R42-Y46 HydrophobicContact CG-CE1 3.81Å; R42-Y46 PolarHBondContact NE-OH 3.02Å; R42-Y46 VanDerWaalsContact NE-OH 3.09Å; R42-Y46 WeakPolarHBondContact O-CE1 3.46Å; T43-Y46 PolarHBondContact O-N 3.36Å; T43-Y46 VanDerWaalsContact O-N 3.13Å; Y46-S48 VanDerWaalsContact C-N 3.29Å; Y46-S48 PolarHBondContact O-N 2.63Å; Y46-W49 WeakPolarHBondContact O-CB 3.31Å; Y46-W49 PolarHBondContact O-N 2.99Å; Y46-V50 HydrophobicContact CD2-CG2 3.76Å; Y46-V50 PolarHBondContact O-N 3.4Å; Y46-D72 WeakPolarHBondContact CE2-OD1 3.32Å; Y46-D72 PolarHBondContact OH-OD1 3.26Å; Y46-M75 HydrophobicContact CE2-CE 4.29Å; Y46-M75 HydrophobicContact CE2-SD 4.35Å; Y46-Y196 HydrophobicContact CD1-CD1 4.39Å; Y46-Y196 HydrophobicContact CD1-CE1 4.26Å; Y46-Y196 AromaticContact CE1-CD1 3.81Å; Y46-Y196 HydrophobicContact CE1-CD1 3.81Å; Y46-Y196 AromaticContact CE1-CE1 3.93Å; Y46-Y196 HydrophobicContact CE1-CE1 3.93Å; Y46-F272 AromaticContact CD1-CE2 3.84Å; Y46-F272 HydrophobicContact CD1-CE2 3.84Å; Y46-F272 HydrophobicContact CD1-CZ 4.1Å; Y46-F272 HydrophobicContact CD2-CE1 4.47Å; Y46-F272 HydrophobicContact CD2-CE2 4.43Å; Y46-F272 AromaticContact CD2-CZ 3.94Å; Y46-F272 HydrophobicContact CD2-CZ 3.94Å; Y46-F272 HydrophobicContact CG-CD2 4.28Å; Y46-F272 HydrophobicContact CG-CE1 4.3Å; Y46-F272 AromaticContact CG-CE2 3.59Å; Y46-F272 HydrophobicContact CG-CE2 3.59Å; Y46-F272 AromaticContact CG-CZ 3.54Å; Y46-F272 HydrophobicContact CG-CZ 3.54Å
47K92.3Very high85.3Confident59 Ų5959.6 Ų59.626%0.25730%0.301SS..Hα-helixtrans-50.9-50.8177.8174.5173.2-177.61780110.7T43 W49 V50 V51 M75 E79T43-K47 WeakPolarHBondContact O-CA 3.47Å; T43-K47 WeakPolarHBondContact O-CB 3.37Å; T43-K47 PolarHBondContact O-N 3.41Å; K47-W49 VanDerWaalsContact C-N 3.29Å; K47-W49 PolarHBondContact O-N 3.41Å; K47-V50 PolarHBondContact O-N 3.31Å; K47-V51 HydrophobicContact CG-CG2 4.03Å; K47-V51 WeakPolarHBondContact O-CB 3.2Å; K47-V51 WeakPolarHBondContact O-CG2 3.5Å; K47-V51 PolarHBondContact O-N 3.33Å; K47-M75 HydrophobicContact CB-SD 3.53Å; K47-M75 VanDerWaalsContact CB-SD 3.53Å; K47-M75 HydrophobicContact CD-CG 3.9Å; K47-M75 HydrophobicContact CD-SD 4.01Å; K47-M75 HydrophobicContact CG-CG 4.04Å; K47-M75 HydrophobicContact CG-SD 3.59Å; K47-M75 VanDerWaalsContact CG-SD 3.59Å; K47-E79 VanDerWaalsContact CE-CD 3.49Å; K47-E79 WeakPolarHBondContact CE-OE1 3.47Å; K47-E79 IonicContact NZ-OE1 2.71Å; K47-E79 PolarHBondContact NZ-OE1 2.92Å
48S93.3Very high86.9Confident79 Ų7960.8 Ų60.855%0.55231%0.313SS*.Hα-helixtrans-58.9-42.6-179.661.60000111.6Y46 S52Y46-S48 VanDerWaalsContact C-N 3.29Å; Y46-S48 PolarHBondContact O-N 2.63Å; S48-S52 WeakPolarHBondContact O-CB 3.12Å; S48-S52 PolarHBondContact O-N 3.44Å; S48-S52 PolarHBondContact O-OG 3.25Å
49W95.9Very high88.5Confident49 Ų4956.8 Ų56.819%0.18629%0.292CS..Hα-helixtrans-66.3-52.7178.4-174.696.4000111.8Y46 K47 S52 L53 I174 Y269 F272 I287 V289Y46-W49 WeakPolarHBondContact O-CB 3.31Å; Y46-W49 PolarHBondContact O-N 2.99Å; K47-W49 VanDerWaalsContact C-N 3.29Å; K47-W49 PolarHBondContact O-N 3.41Å; W49-S52 PolarHBondContact O-N 2.88Å; W49-L53 HydrophobicContact CE3-CD2 4.44Å; W49-L53 HydrophobicContact CH2-CD2 3.57Å; W49-L53 HydrophobicContact CZ2-CD2 4.15Å; W49-L53 HydrophobicContact CZ3-CD2 3.73Å; W49-L53 WeakPolarHBondContact O-CB 3.48Å; W49-L53 PolarHBondContact O-N 3.39Å; W49-I174 HydrophobicContact CZ3-CG2 4.34Å; W49-Y269 HydrophobicContact CH2-CD2 4.27Å; W49-Y269 HydrophobicContact CZ2-CD1 4.12Å; W49-Y269 AromaticContact CZ2-CD2 3.82Å; W49-Y269 HydrophobicContact CZ2-CD2 3.82Å; W49-Y269 HydrophobicContact CZ2-CE1 4.27Å; W49-Y269 AromaticContact CZ2-CE2 3.99Å; W49-Y269 HydrophobicContact CZ2-CE2 3.99Å; W49-Y269 AromaticContact CZ2-CG 3.89Å; W49-Y269 HydrophobicContact CZ2-CG 3.89Å; W49-F272 HydrophobicContact CB-CB 4.34Å; W49-F272 HydrophobicContact CD2-CB 4.16Å; W49-F272 AromaticContact CD2-CD1 3.82Å; W49-F272 HydrophobicContact CD2-CD1 3.82Å; W49-F272 HydrophobicContact CD2-CG 4.46Å; W49-F272 AromaticContact CE3-CD1 3.44Å; W49-F272 HydrophobicContact CE3-CD1 3.44Å; W49-F272 VanDerWaalsContact CE3-CD1 3.44Å; W49-F272 AromaticContact CE3-CE1 3.99Å; W49-F272 HydrophobicContact CE3-CE1 3.99Å; W49-F272 HydrophobicContact CE3-CG 4.45Å; W49-F272 HydrophobicContact CG-CB 4.01Å; W49-F272 HydrophobicContact CG-CD1 4.38Å; W49-F272 HydrophobicContact CH2-CD1 4.37Å; W49-F272 AromaticContact CZ3-CD1 3.76Å; W49-F272 HydrophobicContact CZ3-CD1 3.76Å; W49-F272 HydrophobicContact CZ3-CE1 4.09Å; W49-F272 PolarHBondContact NE1-O 3.14Å; W49-I287 HydrophobicContact CH2-CG2 4.06Å; W49-I287 HydrophobicContact CZ3-CG2 4.36Å; W49-V289 HydrophobicContact CH2-CG2 3.63Å; W49-V289 HydrophobicContact CZ2-CG2 4.28Å
50V96.7Very high90Very high1 Ų159.7 Ų59.71%0.00630%0.302CS..Hα-helixtrans-62.5-50.5-177.7172.30000110.2Y46 K47 S52 L53 L54 L76 F272Y46-V50 HydrophobicContact CD2-CG2 3.76Å; Y46-V50 PolarHBondContact O-N 3.4Å; K47-V50 PolarHBondContact O-N 3.31Å; V50-S52 VanDerWaalsContact C-N 3.34Å; V50-S52 PolarHBondContact O-N 3.2Å; V50-L53 PolarHBondContact O-N 3.19Å; V50-L54 HydrophobicContact CG1-CD1 3.65Å; V50-L54 HydrophobicContact CG1-CG 4.26Å; V50-L54 WeakPolarHBondContact O-CB 3.24Å; V50-L54 WeakPolarHBondContact O-CG 3.14Å; V50-L54 PolarHBondContact O-N 2.99Å; V50-L76 HydrophobicContact CG1-CD2 4.38Å; V50-F272 HydrophobicContact CG2-CE1 4.06Å
51V97.4Very high91.4Very high9 Ų955.7 Ų55.76%0.05529%0.286CS..Hα-helixtrans-62.8-41-179.3173.50000111.3K47 L54 K55 L76 E79 F81K47-V51 HydrophobicContact CG-CG2 4.03Å; K47-V51 WeakPolarHBondContact O-CB 3.2Å; K47-V51 WeakPolarHBondContact O-CG2 3.5Å; K47-V51 PolarHBondContact O-N 3.33Å; V51-L54 PolarHBondContact O-N 3.38Å; V51-K55 HydrophobicContact CG1-CD 3.82Å; V51-K55 VanDerWaalsContact CG1-CE 3.49Å; V51-K55 HydrophobicContact CG1-CG 4.38Å; V51-K55 WeakPolarHBondContact O-CB 3.33Å; V51-K55 VanDerWaalsContact O-CG 3.31Å; V51-K55 WeakPolarHBondContact O-CG 3.48Å; V51-K55 PolarHBondContact O-N 3.25Å; V51-L76 HydrophobicContact CG2-CD2 4.29Å; V51-E79 HydrophobicContact CG2-CB 4.42Å; V51-E79 HydrophobicContact CG2-CG 3.83Å; V51-F81 HydrophobicContact CG1-CE2 4.37Å
52S97.2Very high92.8Very high72 Ų7254 Ų5450%0.50328%0.275SS..Hα-helixtrans-64.9-43.5177.3-610000111.5S48 W49 V50 K55 Q56S48-S52 WeakPolarHBondContact O-CB 3.12Å; S48-S52 PolarHBondContact O-N 3.44Å; S48-S52 PolarHBondContact O-OG 3.25Å; W49-S52 PolarHBondContact O-N 2.88Å; V50-S52 VanDerWaalsContact C-N 3.34Å; V50-S52 PolarHBondContact O-N 3.2Å; S52-K55 PolarHBondContact O-N 3.45Å; S52-Q56 VanDerWaalsContact O-CB 3.3Å; S52-Q56 WeakPolarHBondContact O-CB 3.42Å; S52-Q56 PolarHBondContact O-N 2.98Å
53L97.8Very high94.1Very high16 Ų1653.5 Ų53.58%0.08427%0.273CS..Hα-helixtrans-61.5-45.3177.1-178.967.2000111.7W49 V50 Q56 H57 I172 I174 V289W49-L53 HydrophobicContact CE3-CD2 4.44Å; W49-L53 HydrophobicContact CH2-CD2 3.57Å; W49-L53 HydrophobicContact CZ2-CD2 4.15Å; W49-L53 HydrophobicContact CZ3-CD2 3.73Å; W49-L53 WeakPolarHBondContact O-CB 3.48Å; W49-L53 PolarHBondContact O-N 3.39Å; V50-L53 PolarHBondContact O-N 3.19Å; L53-Q56 PolarHBondContact O-N 3.22Å; L53-H57 PolarHBondContact O-N 3.25Å; L53-H57 PolarHBondContact O-ND1 3Å; L53-I172 HydrophobicContact CD2-CD1 4.47Å; L53-I172 HydrophobicContact CG-CD1 4.29Å; L53-I174 HydrophobicContact CD2-CD1 3.82Å; L53-I174 HydrophobicContact CD2-CG1 4.33Å; L53-V289 HydrophobicContact CD2-CG1 4.1Å; L53-V289 HydrophobicContact CD2-CG2 3.86Å
54L98.4Very high95.2Very high0 Ų052.9 Ų52.90%027%0.269CS..Hα-helixtrans-62.8-46.3177.5-66.8167.5000111V50 V51 Q56 H57 G58 V59 I62 L76 F81 A135 I172 I174V50-L54 HydrophobicContact CG1-CD1 3.65Å; V50-L54 HydrophobicContact CG1-CG 4.26Å; V50-L54 WeakPolarHBondContact O-CB 3.24Å; V50-L54 WeakPolarHBondContact O-CG 3.14Å; V50-L54 PolarHBondContact O-N 2.99Å; V51-L54 PolarHBondContact O-N 3.38Å; L54-Q56 PolarHBondContact O-N 2.89Å; L54-H57 PolarHBondContact O-N 3.29Å; L54-G58 PolarHBondContact O-N 2.82Å; L54-V59 HydrophobicContact CB-CB 4.08Å; L54-V59 HydrophobicContact CB-CG1 4.4Å; L54-V59 HydrophobicContact CB-CG2 4.44Å; L54-V59 HydrophobicContact CD2-CB 4.17Å; L54-V59 HydrophobicContact CD2-CG1 3.88Å; L54-V59 HydrophobicContact CD2-CG2 4.06Å; L54-V59 WeakPolarHBondContact O-CB 3.17Å; L54-V59 WeakPolarHBondContact O-CG2 3.38Å; L54-V59 PolarHBondContact O-N 2.9Å; L54-I62 HydrophobicContact CD1-CD1 3.69Å; L54-I62 HydrophobicContact CD2-CD1 4Å; L54-I62 HydrophobicContact CG-CD1 4.43Å; L54-L76 HydrophobicContact CD1-CD1 4.4Å; L54-L76 HydrophobicContact CD1-CD2 3.57Å; L54-F81 HydrophobicContact CB-CE1 3.87Å; L54-F81 HydrophobicContact CB-CZ 3.66Å; L54-F81 HydrophobicContact CD1-CE1 4.42Å; L54-F81 HydrophobicContact CD1-CE2 4.14Å; L54-F81 HydrophobicContact CD1-CZ 3.99Å; L54-F81 HydrophobicContact CG-CZ 4.5Å; L54-A135 HydrophobicContact CD2-CB 3.64Å; L54-I172 HydrophobicContact CD2-CD1 4.27Å; L54-I174 HydrophobicContact CD2-CD1 4.2Å
55K97.8Very high96Very high120 Ų12046.2 Ų46.252%0.52224%0.238SC..Hα-helixtrans-63-41.2177.1-75175.7-179.7165.40111.9V51 S52 H57 G58 E79 F81V51-K55 HydrophobicContact CG1-CD 3.82Å; V51-K55 VanDerWaalsContact CG1-CE 3.49Å; V51-K55 HydrophobicContact CG1-CG 4.38Å; V51-K55 WeakPolarHBondContact O-CB 3.33Å; V51-K55 VanDerWaalsContact O-CG 3.31Å; V51-K55 WeakPolarHBondContact O-CG 3.48Å; V51-K55 PolarHBondContact O-N 3.25Å; S52-K55 PolarHBondContact O-N 3.45Å; K55-H57 PolarHBondContact O-N 3.38Å; K55-G58 PolarHBondContact O-N 3.19Å; K55-E79 IonicContact NZ-OE2 3.44Å; K55-E79 PolarHBondContact NZ-OE2 2.97Å; K55-F81 HydrophobicContact CG-CZ 4.24Å
56Q97.4Very high96.9Very high158 Ų15843.5 Ų43.574%0.73823%0.227SC*.Hα-helixtrans-60.3-34176.3-178.5-179.4-9.600112.5S52 L53 L54 G58S52-Q56 VanDerWaalsContact O-CB 3.3Å; S52-Q56 WeakPolarHBondContact O-CB 3.42Å; S52-Q56 PolarHBondContact O-N 2.98Å; L53-Q56 PolarHBondContact O-N 3.22Å; L54-Q56 PolarHBondContact O-N 2.89Å; Q56-G58 VanDerWaalsContact C-N 3.31Å
57H97.2Very high97.3Very high57 Ų5743.8 Ų43.826%0.26423%0.229SC..THydrogen-bonded Turntrans-87.94.9176.6-71.382.9000113.6L53 L54 K55 V59 I172L53-H57 PolarHBondContact O-N 3.25Å; L53-H57 PolarHBondContact O-ND1 3Å; L54-H57 PolarHBondContact O-N 3.29Å; K55-H57 PolarHBondContact O-N 3.38Å; H57-V59 HydrophobicContact CB-CG2 3.97Å; H57-V59 PolarHBondContact O-N 3.42Å; H57-I172 HydrophobicContact CB-CD1 4.33Å
58G97.6Very high97.4Very high46 Ų4641.4 Ų41.447%0.47422%0.221SC..THydrogen-bonded Turntrans6329.3-179.300000113.4L54 K55 Q56L54-G58 PolarHBondContact O-N 2.82Å; K55-G58 PolarHBondContact O-N 3.19Å; Q56-G58 VanDerWaalsContact C-N 3.31Å
59V98.4Very high97.5Very high10 Ų1038.2 Ų38.26%0.06120%0.198CC..  trans-67.3136.8-177.2169.10000110.8L54 H57 I62 F81 D134 A135 I172L54-V59 HydrophobicContact CB-CB 4.08Å; L54-V59 HydrophobicContact CB-CG1 4.4Å; L54-V59 HydrophobicContact CB-CG2 4.44Å; L54-V59 HydrophobicContact CD2-CB 4.17Å; L54-V59 HydrophobicContact CD2-CG1 3.88Å; L54-V59 HydrophobicContact CD2-CG2 4.06Å; L54-V59 WeakPolarHBondContact O-CB 3.17Å; L54-V59 WeakPolarHBondContact O-CG2 3.38Å; L54-V59 PolarHBondContact O-N 2.9Å; H57-V59 HydrophobicContact CB-CG2 3.97Å; H57-V59 PolarHBondContact O-N 3.42Å; V59-I62 HydrophobicContact CG1-CD1 3.83Å; V59-I62 HydrophobicContact CG1-CG1 3.47Å; V59-I62 VanDerWaalsContact CG1-CG1 3.47Å; V59-F81 HydrophobicContact CB-CE1 4.37Å; V59-F81 HydrophobicContact CG1-CD1 4.22Å; V59-F81 HydrophobicContact CG1-CE1 4.22Å; V59-F81 WeakPolarHBondContact O-CE1 3.35Å; V59-D134 HydrophobicContact CB-CB 4.18Å; V59-D134 HydrophobicContact CG1-CB 3.95Å; V59-D134 HydrophobicContact CG2-CB 4.12Å; V59-A135 HydrophobicContact CG1-CB 3.84Å; V59-A135 HydrophobicContact CG2-CB 3.96Å; V59-I172 HydrophobicContact CG2-CD1 4.45Å; V59-I172 HydrophobicContact CG2-CG1 4.49Å
60Q97.4Very high97.5Very high121 Ų12135.9 Ų35.957%0.56519%0.189SC*.  trans-125.8-42.4173.9-61.9-176.823.200112.4K82 D134Q60-K82 WeakPolarHBondContact O-CB 3.46Å; Q60-K82 PolarHBondContact O-N 2.89Å; Q60-D134 PolarHBondContact N-OD2 3.15Å; Q60-D134 VanDerWaalsContact N-OD2 3.13Å
61R98.4Very high97.3Very high101 Ų10136.6 Ų36.638%0.38119%0.193SC..EExtended strand (participates in β ladder)trans-109.1125.4-179.7-67173.6-67.2-158.61.7110.4K82 F133 D134 A135R61-K82 WeakPolarHBondContact CA-O 3.49Å; R61-K82 HydrophobicContact CG-CB 4.04Å; R61-K82 HydrophobicContact CG-CD 4.17Å; R61-F133 HydrophobicContact CB-CD1 4.29Å; R61-D134 PolarHBondContact N-OD2 3.24Å; R61-D134 IonicContact NE-OD2 3.9Å; R61-D134 WeakPolarHBondContact O-CB 3.49Å; R61-D134 PolarHBondContact O-N 2.86Å; R61-A135 PolarHBondContact O-N 2.85Å
62I98.8Very high97.2Very high0 Ų036.7 Ų36.70%019%0.194CC..EExtended strand (participates in β ladder)trans-124.1134.3-176-53.1178.2000108.9L54 V59 L76 F81 K82 M83 T84 A135 I137L54-I62 HydrophobicContact CD1-CD1 3.69Å; L54-I62 HydrophobicContact CD2-CD1 4Å; L54-I62 HydrophobicContact CG-CD1 4.43Å; V59-I62 HydrophobicContact CG1-CD1 3.83Å; V59-I62 HydrophobicContact CG1-CG1 3.47Å; V59-I62 VanDerWaalsContact CG1-CG1 3.47Å; I62-L76 HydrophobicContact CD1-CD1 3.97Å; I62-L76 HydrophobicContact CD1-CD2 4.48Å; I62-L76 HydrophobicContact CG2-CD1 4.49Å; I62-F81 HydrophobicContact CD1-CB 3.77Å; I62-F81 HydrophobicContact CD1-CD1 3.67Å; I62-F81 HydrophobicContact CD1-CD2 4.22Å; I62-F81 HydrophobicContact CD1-CE1 4.28Å; I62-F81 HydrophobicContact CD1-CG 3.62Å; I62-F81 HydrophobicContact CG1-CB 4.36Å; I62-F81 HydrophobicContact CG1-CD1 4.35Å; I62-K82 PolarHBondContact N-O 3.42Å; I62-M83 HydrophobicContact CB-CE 3.99Å; I62-M83 HydrophobicContact CB-SD 3.58Å; I62-M83 VanDerWaalsContact CB-SD 3.58Å; I62-M83 HydrophobicContact CD1-SD 4.04Å; I62-M83 HydrophobicContact CG1-SD 4.23Å; I62-M83 HydrophobicContact CG2-CE 3.83Å; I62-M83 HydrophobicContact CG2-SD 3.99Å; I62-T84 PolarHBondContact O-N 3.47Å; I62-A135 VanDerWaalsContact CA-O 3.31Å; I62-A135 WeakPolarHBondContact CA-O 3.37Å; I62-A135 HydrophobicContact CG1-CB 4.31Å; I62-A135 HydrophobicContact CG2-CB 4.44Å; I62-I137 HydrophobicContact CG2-CD1 4.33Å; I62-I137 HydrophobicContact CG2-CG1 4.23Å; I62-I137 HydrophobicContact CG2-CG2 4.11Å
63L98.9Very high97.3Very high0 Ų033.3 Ų33.30%017%0.17CC..EExtended strand (participates in β ladder)trans-100.2118.8165.3178.264.6000109.2V65 T84 V86 V126 F133 A135 V136 I137 M166L63-V65 HydrophobicContact CD2-CG1 3.63Å; L63-V65 HydrophobicContact CG-CG1 3.7Å; L63-T84 CarbonylContact C-O 3.19Å; L63-T84 VanDerWaalsContact CA-O 3.29Å; L63-T84 WeakPolarHBondContact CA-O 3.43Å; L63-T84 HydrophobicContact CD1-CG2 3.88Å; L63-V86 HydrophobicContact CD1-CG1 4.47Å; L63-V86 HydrophobicContact CD1-CG2 4.19Å; L63-V126 HydrophobicContact CD1-CG1 4.17Å; L63-V126 HydrophobicContact CD2-CG1 4.47Å; L63-F133 HydrophobicContact CB-CB 4.27Å; L63-F133 HydrophobicContact CB-CD1 3.72Å; L63-F133 HydrophobicContact CB-CD2 3.7Å; L63-F133 HydrophobicContact CB-CE1 3.89Å; L63-F133 HydrophobicContact CB-CE2 3.87Å; L63-F133 HydrophobicContact CB-CG 3.62Å; L63-F133 HydrophobicContact CB-CZ 3.96Å; L63-F133 HydrophobicContact CD1-CE2 4.34Å; L63-F133 HydrophobicContact CD1-CZ 4.13Å; L63-F133 HydrophobicContact CD2-CD2 4.03Å; L63-F133 HydrophobicContact CD2-CE2 3.87Å; L63-F133 HydrophobicContact CD2-CZ 4.47Å; L63-F133 HydrophobicContact CG-CD2 4.43Å; L63-F133 HydrophobicContact CG-CE2 4.25Å; L63-F133 HydrophobicContact CG-CZ 4.41Å; L63-A135 PolarHBondContact N-O 3.31Å; L63-V136 HydrophobicContact CB-CG1 4.38Å; L63-V136 HydrophobicContact CB-CG2 4.23Å; L63-V136 HydrophobicContact CD2-CG1 4.36Å; L63-V136 HydrophobicContact CG-CG1 4.47Å; L63-V136 CarbonylContact O-C 3.49Å; L63-V136 VanDerWaalsContact O-CA 3.26Å; L63-V136 WeakPolarHBondContact O-CA 3.21Å; L63-I137 PolarHBondContact O-N 2.92Å; L63-M166 HydrophobicContact CD2-CB 3.74Å; L63-M166 HydrophobicContact CD2-CG 3.71Å; L63-M166 HydrophobicContact CD2-SD 4.28Å
64D98.9Very high97.3Very high4 Ų433.8 Ų33.82%0.02117%0.173CC..EExtended strand (participates in β ladder)trans-93111166.6-177-2.7000108.7A66 C67 S73 M83 T84 S85 V86 I137D64-A66 VanDerWaalsContact C-N 3.34Å; D64-A66 VanDerWaalsContact OD1-C 3.27Å; D64-A66 PolarHBondContact OD1-N 3.19Å; D64-C67 PolarHBondContact OD1-N 2.84Å; D64-S73 WeakPolarHBondContact CB-OG 3.32Å; D64-S73 PolarHBondContact OD2-OG 3.21Å; D64-M83 HydrophobicContact CB-CE 3.88Å; D64-T84 PolarHBondContact N-O 2.8Å; D64-S85 CarbonylContact O-C 3.57Å; D64-S85 WeakPolarHBondContact O-CA 3.37Å; D64-V86 PolarHBondContact O-N 3.06Å; D64-I137 HydrophobicContact CB-CD1 4.04Å; D64-I137 HydrophobicContact CB-CG1 3.79Å
65V98.8Very high97.2Very high1 Ų134 Ų341%0.00617%0.174CC..SBendtrans-90.20.4-179.6-59.30000113.1L63 V86 W119 L122 V136 I137 C138 I163L63-V65 HydrophobicContact CD2-CG1 3.63Å; L63-V65 HydrophobicContact CG-CG1 3.7Å; V65-V86 CarbonylContact C-O 3.6Å; V65-V86 VanDerWaalsContact C-O 3.3Å; V65-V86 HydrophobicContact CB-CG2 4.36Å; V65-V86 HydrophobicContact CG1-CG2 4.36Å; V65-W119 PolarHBondContact O-NE1 3.38Å; V65-L122 HydrophobicContact CG1-CD1 4.46Å; V65-L122 HydrophobicContact CG1-CD2 3.94Å; V65-V136 HydrophobicContact CG1-CG1 3.81Å; V65-V136 HydrophobicContact CG2-CG1 4.43Å; V65-I137 WeakPolarHBondContact CG2-O 3.44Å; V65-I137 PolarHBondContact N-O 3.24Å; V65-C138 HydrophobicContact CG2-CB 3.61Å; V65-I163 HydrophobicContact CG2-CD1 4.15Å; V65-I163 HydrophobicContact CG2-CG1 4.25Å; V65-I163 HydrophobicContact CG2-CG2 4.49Å
66A97.9Very high97.2Very high11 Ų1128.4 Ų28.49%0.09115%0.149CC..  trans-134.452.7178.700000109.8D64 G68 W119 S142D64-A66 VanDerWaalsContact C-N 3.34Å; D64-A66 VanDerWaalsContact OD1-C 3.27Å; D64-A66 PolarHBondContact OD1-N 3.19Å; A66-G68 PolarHBondContact O-N 3.26Å; A66-G68 VanDerWaalsContact O-N 3.15Å; A66-W119 HydrophobicContact CB-CZ2 4.3Å; A66-S142 VanDerWaalsContact CB-CB 3.48Å
67C97.6Very high97.3Very high5 Ų521 Ų213%0.03412%0.115CC..  trans-53-40.7-171.2-1800000112.2D64 T69 G70 S85 V86 D87 L93D64-C67 PolarHBondContact OD1-N 2.84Å; C67-T69 PolarHBondContact O-N 2.98Å; C67-G70 VanDerWaalsContact O-CA 3.28Å; C67-G70 WeakPolarHBondContact O-CA 3.46Å; C67-G70 PolarHBondContact O-N 2.84Å; C67-S85 WeakPolarHBondContact SG-CB 3.43Å; C67-V86 VanDerWaalsContact CB-O 3.28Å; C67-V86 WeakPolarHBondContact CB-O 3.34Å; C67-V86 PolarHBondContact N-O 3.23Å; C67-D87 HydrophobicContact CB-CB 4.16Å; C67-L93 HydrophobicContact CB-CD2 3.97Å
68G94.6Very high97.3Very high9 Ų923 Ų239%0.09312%0.124CC..THydrogen-bonded Turntrans53.4-126.1-175.200000110.9A66 G70 D87 M92A66-G68 PolarHBondContact O-N 3.26Å; A66-G68 VanDerWaalsContact O-N 3.15Å; G68-G70 PolarHBondContact O-N 2.91Å; G68-D87 WeakPolarHBondContact CA-OD2 3.38Å; G68-D87 PolarHBondContact N-OD2 3Å; G68-M92 CarbonylContact O-C 3.48Å; G68-M92 VanDerWaalsContact O-O 3.13Å
69T93.7Very high97.3Very high13 Ų1323.9 Ų23.98%0.0812%0.116CC..THydrogen-bonded Turntrans-84.35.2174.859.80000113.6C67 M92 Y95C67-T69 PolarHBondContact O-N 2.98Å; T69-M92 HydrophobicContact CG2-CE 4.14Å; T69-M92 HydrophobicContact CG2-SD 4.17Å; T69-Y95 HydrophobicContact CG2-CD2 3.98Å; T69-Y95 HydrophobicContact CG2-CG 4.02Å
70G95.9Very high97.3Very high0 Ų026.4 Ų26.40%014%0.144CC..SBendtrans90.77.4174.200000115.8C67 G68 D72 S73 I74C67-G70 VanDerWaalsContact O-CA 3.28Å; C67-G70 WeakPolarHBondContact O-CA 3.46Å; C67-G70 PolarHBondContact O-N 2.84Å; G68-G70 PolarHBondContact O-N 2.91Å; G70-D72 PolarHBondContact O-N 2.89Å; G70-S73 CarbonylContact O-C 3.54Å; G70-S73 PolarHBondContact O-N 3.27Å; G70-S73 VanDerWaalsContact O-N 3.16Å; G70-I74 WeakPolarHBondContact O-CB 3.4Å; G70-I74 VanDerWaalsContact O-CD1 3.28Å; G70-I74 WeakPolarHBondContact O-CD1 3.32Å; G70-I74 WeakPolarHBondContact O-CG1 3.3Å; G70-I74 PolarHBondContact O-N 2.97Å
71V93.4Very high97.3Very high15 Ų1521.5 Ų21.59%0.09112%0.121CC..Hα-helixtrans-55.2-50.5-169.8178.40000113I36 T39 T43 M75I36-V71 HydrophobicContact CD1-CG2 4.07Å; T39-V71 HydrophobicContact CG2-CG1 4.27Å; T39-V71 HydrophobicContact CG2-CG2 3.79Å; T43-V71 HydrophobicContact CG2-CG1 3.96Å; V71-M75 PolarHBondContact O-N 2.77Å
72D96Very high97.3Very high12 Ų1222.6 Ų22.66%0.06413%0.128CC..Hα-helixtrans-69.1-40.5179.4-70.3-62.4000111.7R42 Y46 G70 M75 L76R42-D72 IonicContact CZ-OD2 3.49Å; R42-D72 IonicContact NH2-OD2 2.68Å; R42-D72 PolarHBondContact NH2-OD2 2.99Å; Y46-D72 WeakPolarHBondContact CE2-OD1 3.32Å; Y46-D72 PolarHBondContact OH-OD1 3.26Å; G70-D72 PolarHBondContact O-N 2.89Å; D72-M75 PolarHBondContact O-N 2.88Å; D72-L76 WeakPolarHBondContact O-CG 3.26Å; D72-L76 PolarHBondContact O-N 3.4Å; D72-L76 VanDerWaalsContact O-N 3.15Å
73S98.3Very high97.3Very high0 Ų022.9 Ų22.90%013%0.129CC..Hα-helixtrans-62.9-45.8176.8-76.30000113D64 G70 M75 L76 V77 S85D64-S73 WeakPolarHBondContact CB-OG 3.32Å; D64-S73 PolarHBondContact OD2-OG 3.21Å; G70-S73 CarbonylContact O-C 3.54Å; G70-S73 PolarHBondContact O-N 3.27Å; G70-S73 VanDerWaalsContact O-N 3.16Å; S73-M75 VanDerWaalsContact C-N 3.35Å; S73-M75 PolarHBondContact O-N 2.92Å; S73-L76 PolarHBondContact O-N 2.74Å; S73-L76 VanDerWaalsContact O-N 3.13Å; S73-V77 WeakPolarHBondContact O-CG2 3.41Å; S73-V77 PolarHBondContact O-N 2.92Å; S73-S85 WeakPolarHBondContact CB-OG 2.99Å; S73-S85 WeakPolarHBondContact OG-CB 3.16Å; S73-S85 PolarHBondContact OG-OG 3.2Å
74I97.6Very high97.3Very high27 Ų2724.2 Ų24.214%0.13814%0.138CC..Hα-helixtrans-58-48.5177.4-69.1156.5000109.9G70 L76 V77 E78 E99 F109 W112G70-I74 WeakPolarHBondContact O-CB 3.4Å; G70-I74 VanDerWaalsContact O-CD1 3.28Å; G70-I74 WeakPolarHBondContact O-CD1 3.32Å; G70-I74 WeakPolarHBondContact O-CG1 3.3Å; G70-I74 PolarHBondContact O-N 2.97Å; I74-L76 VanDerWaalsContact C-N 3.26Å; I74-L76 PolarHBondContact O-N 3.31Å; I74-V77 PolarHBondContact O-N 3Å; I74-E78 WeakPolarHBondContact O-CG 3.31Å; I74-E78 PolarHBondContact O-N 2.86Å; I74-E99 HydrophobicContact CD1-CB 4.16Å; I74-E99 HydrophobicContact CD1-CG 3.66Å; I74-E99 HydrophobicContact CG1-CG 4.02Å; I74-F109 HydrophobicContact CG1-CE1 4.38Å; I74-F109 HydrophobicContact CG2-CE1 4.16Å; I74-F109 HydrophobicContact CG2-CZ 4.05Å; I74-W112 HydrophobicContact CD1-CH2 4.42Å; I74-W112 HydrophobicContact CG1-CH2 3.74Å; I74-W112 HydrophobicContact CG1-CZ3 3.84Å
75M97Very high97.3Very high5 Ų524 Ų243%0.02514%0.137CC..Hα-helixtrans-55.2-42.4176.6177.8-162.969.900111.7T43 Y46 K47 V71 D72 S73 E78 E79T43-M75 HydrophobicContact CG2-CB 4.14Å; T43-M75 HydrophobicContact CG2-CG 4.26Å; T43-M75 HydrophobicContact CG2-SD 3.77Å; Y46-M75 HydrophobicContact CE2-CE 4.29Å; Y46-M75 HydrophobicContact CE2-SD 4.35Å; K47-M75 HydrophobicContact CB-SD 3.53Å; K47-M75 VanDerWaalsContact CB-SD 3.53Å; K47-M75 HydrophobicContact CD-CG 3.9Å; K47-M75 HydrophobicContact CD-SD 4.01Å; K47-M75 HydrophobicContact CG-CG 4.04Å; K47-M75 HydrophobicContact CG-SD 3.59Å; K47-M75 VanDerWaalsContact CG-SD 3.59Å; V71-M75 PolarHBondContact O-N 2.77Å; D72-M75 PolarHBondContact O-N 2.88Å; S73-M75 VanDerWaalsContact C-N 3.35Å; S73-M75 PolarHBondContact O-N 2.92Å; M75-E78 PolarHBondContact O-N 2.85Å; M75-E79 WeakPolarHBondContact O-CG 3.4Å; M75-E79 PolarHBondContact O-N 2.71Å; M75-E79 VanDerWaalsContact O-N 3.13Å
76L98.3Very high97.3Very high1 Ų124.1 Ų24.11%0.00514%0.137CC..Hα-helixtrans-77.3-31.9-178.8-66.6173.9000113.1V50 V51 L54 I62 D72 S73 I74 E78 E79 G80 F81 M83 I137V50-L76 HydrophobicContact CG1-CD2 4.38Å; V51-L76 HydrophobicContact CG2-CD2 4.29Å; L54-L76 HydrophobicContact CD1-CD1 4.4Å; L54-L76 HydrophobicContact CD1-CD2 3.57Å; I62-L76 HydrophobicContact CD1-CD1 3.97Å; I62-L76 HydrophobicContact CD1-CD2 4.48Å; I62-L76 HydrophobicContact CG2-CD1 4.49Å; D72-L76 WeakPolarHBondContact O-CG 3.26Å; D72-L76 PolarHBondContact O-N 3.4Å; D72-L76 VanDerWaalsContact O-N 3.15Å; S73-L76 PolarHBondContact O-N 2.74Å; S73-L76 VanDerWaalsContact O-N 3.13Å; I74-L76 VanDerWaalsContact C-N 3.26Å; I74-L76 PolarHBondContact O-N 3.31Å; L76-E78 VanDerWaalsContact C-N 3.33Å; L76-E79 PolarHBondContact O-N 3.13Å; L76-G80 PolarHBondContact O-N 2.86Å; L76-F81 HydrophobicContact CB-CB 4.38Å; L76-F81 HydrophobicContact CB-CD2 4.11Å; L76-F81 HydrophobicContact CD2-CD2 3.77Å; L76-F81 HydrophobicContact CD2-CE2 3.89Å; L76-F81 WeakPolarHBondContact O-CB 3.18Å; L76-F81 WeakPolarHBondContact O-CD2 3.39Å; L76-F81 PolarHBondContact O-N 3.02Å; L76-M83 HydrophobicContact CB-CE 4.43Å; L76-M83 HydrophobicContact CB-CG 4.09Å; L76-M83 HydrophobicContact CB-SD 3.49Å; L76-M83 WeakPolarHBondContact CB-SD 3.17Å; L76-M83 HydrophobicContact CD1-CE 4.11Å; L76-M83 HydrophobicContact CD1-SD 3.92Å; L76-M83 HydrophobicContact CG-SD 4.37Å; L76-I137 HydrophobicContact CD1-CD1 3.65Å
77V98.4Very high97.2Very high2 Ų224.8 Ų24.81%0.01214%0.139CC..Hα-helixtrans-60.2-45.8168.8172.20000110S73 I74 E79 G80 M83 A108 F109 W112S73-V77 WeakPolarHBondContact O-CG2 3.41Å; S73-V77 PolarHBondContact O-N 2.92Å; I74-V77 PolarHBondContact O-N 3Å; V77-E79 VanDerWaalsContact C-N 3.28Å; V77-E79 PolarHBondContact O-N 3.13Å; V77-G80 PolarHBondContact O-N 3.38Å; V77-M83 HydrophobicContact CG2-CB 3.8Å; V77-M83 HydrophobicContact CG2-CG 3.54Å; V77-A108 HydrophobicContact CG1-CB 3.68Å; V77-F109 HydrophobicContact CB-CE2 4.48Å; V77-F109 HydrophobicContact CB-CZ 4.28Å; V77-F109 HydrophobicContact CG1-CD1 4.23Å; V77-F109 HydrophobicContact CG1-CD2 3.73Å; V77-F109 HydrophobicContact CG1-CE1 4.18Å; V77-F109 HydrophobicContact CG1-CE2 3.64Å; V77-F109 HydrophobicContact CG1-CG 4Å; V77-F109 HydrophobicContact CG1-CZ 3.86Å; V77-W112 HydrophobicContact CG2-CB 3.99Å; V77-W112 HydrophobicContact CG2-CD2 4Å; V77-W112 HydrophobicContact CG2-CE3 4.46Å; V77-W112 HydrophobicContact CG2-CG 3.77Å
78E97.3Very high97Very high100 Ų10025.5 Ų25.547%0.46715%0.146SC..Hα-helixtrans-63.5-32.2177.9-70.5178.8157.300113I74 M75 L76 G80 R103 F109I74-E78 WeakPolarHBondContact O-CG 3.31Å; I74-E78 PolarHBondContact O-N 2.86Å; M75-E78 PolarHBondContact O-N 2.85Å; L76-E78 VanDerWaalsContact C-N 3.33Å; E78-G80 PolarHBondContact O-N 3.38Å; E78-R103 IonicContact OE1-CZ 3.49Å; E78-R103 IonicContact OE1-NH1 2.94Å; E78-R103 PolarHBondContact OE1-NH1 3.29Å; E78-R103 IonicContact OE1-NH2 3.97Å; E78-R103 PolarHBondContact OE1-NH2 3.32Å; E78-F109 HydrophobicContact CG-CE2 4.09Å; E78-F109 HydrophobicContact CG-CZ 3.96Å
79E97.8Very high96.8Very high65 Ų6525.2 Ų25.230%0.30414%0.142SC..THydrogen-bonded Turntrans-79.61.3174.5-70.4-68.1141.500113.7K47 V51 K55 M75 L76 V77 F81K47-E79 VanDerWaalsContact CE-CD 3.49Å; K47-E79 WeakPolarHBondContact CE-OE1 3.47Å; K47-E79 IonicContact NZ-OE1 2.71Å; K47-E79 PolarHBondContact NZ-OE1 2.92Å; V51-E79 HydrophobicContact CG2-CB 4.42Å; V51-E79 HydrophobicContact CG2-CG 3.83Å; K55-E79 IonicContact NZ-OE2 3.44Å; K55-E79 PolarHBondContact NZ-OE2 2.97Å; M75-E79 WeakPolarHBondContact O-CG 3.4Å; M75-E79 PolarHBondContact O-N 2.71Å; M75-E79 VanDerWaalsContact O-N 3.13Å; L76-E79 PolarHBondContact O-N 3.13Å; V77-E79 VanDerWaalsContact C-N 3.28Å; V77-E79 PolarHBondContact O-N 3.13Å; E79-F81 HydrophobicContact CB-CD2 3.89Å; E79-F81 HydrophobicContact CB-CE2 3.87Å
80G97.8Very high96.5Very high62 Ų6228.4 Ų28.464%0.63916%0.159SC*.THydrogen-bonded Turntrans88.312.8173.100000115.3L76 V77 E78L76-G80 PolarHBondContact O-N 2.86Å; V77-G80 PolarHBondContact O-N 3.38Å; E78-G80 PolarHBondContact O-N 3.38Å
81F98.5Very high96.1Very high19 Ų1932 Ų328%0.08317%0.174CC..  trans-77.5150.2173.6-63.3-80.7000111.5V51 L54 K55 V59 I62 L76 E79 M83V51-F81 HydrophobicContact CG1-CE2 4.37Å; L54-F81 HydrophobicContact CB-CE1 3.87Å; L54-F81 HydrophobicContact CB-CZ 3.66Å; L54-F81 HydrophobicContact CD1-CE1 4.42Å; L54-F81 HydrophobicContact CD1-CE2 4.14Å; L54-F81 HydrophobicContact CD1-CZ 3.99Å; L54-F81 HydrophobicContact CG-CZ 4.5Å; K55-F81 HydrophobicContact CG-CZ 4.24Å; V59-F81 HydrophobicContact CB-CE1 4.37Å; V59-F81 HydrophobicContact CG1-CD1 4.22Å; V59-F81 HydrophobicContact CG1-CE1 4.22Å; V59-F81 WeakPolarHBondContact O-CE1 3.35Å; I62-F81 HydrophobicContact CD1-CB 3.77Å; I62-F81 HydrophobicContact CD1-CD1 3.67Å; I62-F81 HydrophobicContact CD1-CD2 4.22Å; I62-F81 HydrophobicContact CD1-CE1 4.28Å; I62-F81 HydrophobicContact CD1-CG 3.62Å; I62-F81 HydrophobicContact CG1-CB 4.36Å; I62-F81 HydrophobicContact CG1-CD1 4.35Å; L76-F81 HydrophobicContact CB-CB 4.38Å; L76-F81 HydrophobicContact CB-CD2 4.11Å; L76-F81 HydrophobicContact CD2-CD2 3.77Å; L76-F81 HydrophobicContact CD2-CE2 3.89Å; L76-F81 WeakPolarHBondContact O-CB 3.18Å; L76-F81 WeakPolarHBondContact O-CD2 3.39Å; L76-F81 PolarHBondContact O-N 3.02Å; E79-F81 HydrophobicContact CB-CD2 3.89Å; E79-F81 HydrophobicContact CB-CE2 3.87Å; F81-M83 HydrophobicContact CB-SD 4.29Å; F81-M83 PolarHBondContact O-N 2.86Å
82K98.4Very high95.8Very high124 Ų12431.6 Ų31.654%0.53917%0.171SC..EExtended strand (participates in β ladder)trans-86.3101.7173.6-65.5176.5-177.9172.60108.9Q60 R61 I62Q60-K82 WeakPolarHBondContact O-CB 3.46Å; Q60-K82 PolarHBondContact O-N 2.89Å; R61-K82 WeakPolarHBondContact CA-O 3.49Å; R61-K82 HydrophobicContact CG-CB 4.04Å; R61-K82 HydrophobicContact CG-CD 4.17Å; I62-K82 PolarHBondContact N-O 3.42Å
83M98.4Very high95.6Very high5 Ų531.3 Ų31.33%0.02517%0.17CC..EExtended strand (participates in β ladder)trans-91.7134.3-176.2-65.6-56.5-56.300112.3I62 D64 L76 V77 F81 W112 V113I62-M83 HydrophobicContact CB-CE 3.99Å; I62-M83 HydrophobicContact CB-SD 3.58Å; I62-M83 VanDerWaalsContact CB-SD 3.58Å; I62-M83 HydrophobicContact CD1-SD 4.04Å; I62-M83 HydrophobicContact CG1-SD 4.23Å; I62-M83 HydrophobicContact CG2-CE 3.83Å; I62-M83 HydrophobicContact CG2-SD 3.99Å; D64-M83 HydrophobicContact CB-CE 3.88Å; L76-M83 HydrophobicContact CB-CE 4.43Å; L76-M83 HydrophobicContact CB-CG 4.09Å; L76-M83 HydrophobicContact CB-SD 3.49Å; L76-M83 WeakPolarHBondContact CB-SD 3.17Å; L76-M83 HydrophobicContact CD1-CE 4.11Å; L76-M83 HydrophobicContact CD1-SD 3.92Å; L76-M83 HydrophobicContact CG-SD 4.37Å; V77-M83 HydrophobicContact CG2-CB 3.8Å; V77-M83 HydrophobicContact CG2-CG 3.54Å; F81-M83 HydrophobicContact CB-SD 4.29Å; F81-M83 PolarHBondContact O-N 2.86Å; M83-W112 HydrophobicContact CB-CG 4.39Å; M83-V113 PolarHBondContact O-N 3.26Å; M83-V113 VanDerWaalsContact O-N 3.15Å
84T98.8Very high95.3Very high29 Ų2938 Ų3818%0.17820%0.199CC..EExtended strand (participates in β ladder)trans-116.6128.6154.2-60.40000107I62 L63 D64 V113 F133I62-T84 PolarHBondContact O-N 3.47Å; L63-T84 CarbonylContact C-O 3.19Å; L63-T84 VanDerWaalsContact CA-O 3.29Å; L63-T84 WeakPolarHBondContact CA-O 3.43Å; L63-T84 HydrophobicContact CD1-CG2 3.88Å; D64-T84 PolarHBondContact N-O 2.8Å; T84-V113 CarbonylContact C-O 3.19Å; T84-V113 WeakPolarHBondContact CA-O 3.41Å; T84-V113 HydrophobicContact CG2-CB 4.16Å; T84-V113 HydrophobicContact CG2-CG1 3.98Å; T84-F133 HydrophobicContact CG2-CZ 4.39Å
85S98.8Very high95.1Very high0 Ų039.2 Ų39.20%020%0.202CC..EExtended strand (participates in β ladder)trans-129.6131.6-174.1-48.60000110.1D64 C67 S73 W112 V113 I114 E115D64-S85 CarbonylContact O-C 3.57Å; D64-S85 WeakPolarHBondContact O-CA 3.37Å; C67-S85 WeakPolarHBondContact SG-CB 3.43Å; S73-S85 WeakPolarHBondContact CB-OG 2.99Å; S73-S85 WeakPolarHBondContact OG-CB 3.16Å; S73-S85 PolarHBondContact OG-OG 3.2Å; S85-W112 PolarHBondContact OG-NE1 2.91Å; S85-V113 PolarHBondContact N-O 3.03Å; S85-I114 VanDerWaalsContact O-CA 3.29Å; S85-I114 WeakPolarHBondContact O-CA 2.84Å; S85-E115 PolarHBondContact O-N 3.41Å; S85-E115 VanDerWaalsContact O-N 3.07Å
86V98.4Very high95Very high2 Ų239 Ų391%0.01220%0.201CC..EExtended strand (participates in β ladder)trans-132.8150.9-177.9-61.40000111.4L63 D64 V65 C67 E115 A117 L122 V126L63-V86 HydrophobicContact CD1-CG1 4.47Å; L63-V86 HydrophobicContact CD1-CG2 4.19Å; D64-V86 PolarHBondContact O-N 3.06Å; V65-V86 CarbonylContact C-O 3.6Å; V65-V86 VanDerWaalsContact C-O 3.3Å; V65-V86 HydrophobicContact CB-CG2 4.36Å; V65-V86 HydrophobicContact CG1-CG2 4.36Å; C67-V86 VanDerWaalsContact CB-O 3.28Å; C67-V86 WeakPolarHBondContact CB-O 3.34Å; C67-V86 PolarHBondContact N-O 3.23Å; V86-E115 VanDerWaalsContact CA-O 3.25Å; V86-E115 WeakPolarHBondContact CA-O 3.41Å; V86-E115 HydrophobicContact CG1-CB 4.22Å; V86-A117 HydrophobicContact CB-CB 3.65Å; V86-A117 HydrophobicContact CG1-CB 3.94Å; V86-A117 HydrophobicContact CG2-CB 3.89Å; V86-L122 HydrophobicContact CG2-CD1 4.06Å; V86-V126 HydrophobicContact CG1-CG2 3.82Å; V86-V126 HydrophobicContact CG2-CG2 4.38Å
87D97.3Very high94.9Very high26 Ų2642.2 Ų42.214%0.13922%0.218CC..EExtended strand (participates in β ladder)trans-151.3157172.7-155.3-72.8000109C67 G68 S89 L93 E116 A117C67-D87 HydrophobicContact CB-CB 4.16Å; G68-D87 WeakPolarHBondContact CA-OD2 3.38Å; G68-D87 PolarHBondContact N-OD2 3Å; D87-S89 WeakPolarHBondContact OD1-CB 3.44Å; D87-S89 PolarHBondContact OD1-N 2.89Å; D87-L93 HydrophobicContact CB-CD1 4.19Å; D87-L93 HydrophobicContact CB-CD2 3.55Å; D87-L93 HydrophobicContact CB-CG 3.71Å; D87-E116 WeakPolarHBondContact O-CA 3.29Å; D87-A117 CarbonylContact C-O 3.57Å; D87-A117 PolarHBondContact O-N 3.41Å
88A93.3Very high94.9Very high20 Ų2047.8 Ų47.817%0.16524%0.242CC..SBendtrans-85.4-17.5175.100000112.2L19 A117L19-A88 HydrophobicContact CD2-CB 3.81Å; A88-A117 WeakPolarHBondContact CA-O 3.25Å; A88-A117 PolarHBondContact N-O 2.75Å
89S90Very high94.8Very high2 Ų245.9 Ų45.91%0.01423%0.233CC..  trans-95.8107.2-178.5-173.40000111.9D21 D87 K91 M92 L93D21-S89 PolarHBondContact OD1-OG 3.43Å; D21-S89 PolarHBondContact OD2-OG 2.8Å; D87-S89 WeakPolarHBondContact OD1-CB 3.44Å; D87-S89 PolarHBondContact OD1-N 2.89Å; S89-K91 PolarHBondContact O-N 2.88Å; S89-M92 PolarHBondContact O-N 3.26Å; S89-M92 VanDerWaalsContact O-N 3.07Å; S89-L93 PolarHBondContact O-N 2.95Å
90D86.4Confident94.8Very high81 Ų8146.1 Ų46.143%0.43323%0.231SC..Hα-helixtrans-57.2-32.4173.579.9-35.2000112.2M92 K94D90-M92 VanDerWaalsContact C-N 3.32Å; D90-M92 PolarHBondContact O-N 3.44Å; D90-K94 WeakPolarHBondContact O-CB 3.24Å; D90-K94 PolarHBondContact O-N 3.05Å
91K87.4Confident94.8Very high75 Ų7551.1 Ų51.133%0.32623%0.231SC..Hα-helixtrans-64.7-36.1177.9-61.8-62.7168-77.50112.2A29 S89 Y95A29-K91 HydrophobicContact CB-CB 4.19Å; S89-K91 PolarHBondContact O-N 2.88Å; K91-Y95 VanDerWaalsContact O-CD2 3.29Å; K91-Y95 WeakPolarHBondContact O-CD2 3.44Å; K91-Y95 WeakPolarHBondContact O-CE2 3.45Å
92M87.2Confident94.8Very high6 Ų655.3 Ų55.33%0.0325%0.251CS..Hα-helixtrans-79.1-48177.6-64-71.9-80.800110.4Y23 A29 W32 G68 T69 S89 D90 K94 Y95Y23-M92 HydrophobicContact CD1-CG 4.4Å; Y23-M92 HydrophobicContact CD1-SD 4.07Å; Y23-M92 HydrophobicContact CD2-CG 4.36Å; Y23-M92 HydrophobicContact CE1-CE 4.36Å; Y23-M92 HydrophobicContact CE1-SD 4.45Å; Y23-M92 HydrophobicContact CG-CG 4.1Å; Y23-M92 HydrophobicContact CG-SD 4.36Å; A29-M92 HydrophobicContact CB-SD 3.97Å; W32-M92 HydrophobicContact CG-CE 4.17Å; G68-M92 CarbonylContact O-C 3.48Å; G68-M92 VanDerWaalsContact O-O 3.13Å; T69-M92 HydrophobicContact CG2-CE 4.14Å; T69-M92 HydrophobicContact CG2-SD 4.17Å; S89-M92 PolarHBondContact O-N 3.26Å; S89-M92 VanDerWaalsContact O-N 3.07Å; D90-M92 VanDerWaalsContact C-N 3.32Å; D90-M92 PolarHBondContact O-N 3.44Å; M92-K94 PolarHBondContact O-N 2.92Å; M92-K94 VanDerWaalsContact O-N 3.14Å; M92-Y95 PolarHBondContact O-N 2.68Å
93L91.3Very high94.8Very high7 Ų751.9 Ų51.94%0.03723%0.234CC..Hα-helixtrans-57-32.2178.6-72.4-178.6000113.2C67 D87 S89 Y95 A96 L97 I114 E115 E116C67-L93 HydrophobicContact CB-CD2 3.97Å; D87-L93 HydrophobicContact CB-CD1 4.19Å; D87-L93 HydrophobicContact CB-CD2 3.55Å; D87-L93 HydrophobicContact CB-CG 3.71Å; S89-L93 PolarHBondContact O-N 2.95Å; L93-Y95 PolarHBondContact O-N 3.31Å; L93-Y95 VanDerWaalsContact O-N 3.1Å; L93-A96 PolarHBondContact O-N 3.48Å; L93-A96 VanDerWaalsContact O-N 3.09Å; L93-L97 HydrophobicContact CB-CD1 4.47Å; L93-L97 WeakPolarHBondContact O-CB 3.43Å; L93-L97 WeakPolarHBondContact O-CG 3.36Å; L93-L97 PolarHBondContact O-N 2.89Å; L93-I114 HydrophobicContact CD2-CG2 3.79Å; L93-E115 WeakPolarHBondContact CD1-O 3.29Å; L93-E116 HydrophobicContact CD1-CB 4.18Å
94K93.3Very high94.8Very high139 Ų13956.1 Ų56.160%0.60425%0.25SS*.Hα-helixtrans-47.3-40173.4179.4-175.7171.7-175.30112.7D90 M92 K98D90-K94 WeakPolarHBondContact O-CB 3.24Å; D90-K94 PolarHBondContact O-N 3.05Å; M92-K94 PolarHBondContact O-N 2.92Å; M92-K94 VanDerWaalsContact O-N 3.14Å; K94-K98 WeakPolarHBondContact O-CB 3.36Å; K94-K98 PolarHBondContact O-N 3.09Å
95Y92.3Very high94.8Very high54 Ų5463.4 Ų63.421%0.21228%0.28CS..Hα-helixtrans-75.3-41.7-178.9-66.1-89.8000112A29 T69 K91 M92 L93 K98 E99A29-Y95 HydrophobicContact CB-CE2 4.09Å; A29-Y95 PolarHBondContact O-OH 3.28Å; T69-Y95 HydrophobicContact CG2-CD2 3.98Å; T69-Y95 HydrophobicContact CG2-CG 4.02Å; K91-Y95 VanDerWaalsContact O-CD2 3.29Å; K91-Y95 WeakPolarHBondContact O-CD2 3.44Å; K91-Y95 WeakPolarHBondContact O-CE2 3.45Å; M92-Y95 PolarHBondContact O-N 2.68Å; L93-Y95 PolarHBondContact O-N 3.31Å; L93-Y95 VanDerWaalsContact O-N 3.1Å; Y95-K98 WeakPolarHBondContact O-CB 3.3Å; Y95-K98 PolarHBondContact O-N 3.32Å; Y95-E99 PolarHBondContact O-N 3.35Å
96A95.2Very high94.7Very high0 Ų067.4 Ų67.40%030%0.298CS..Hα-helixtrans-62.3-44175.300000111.4L93 K98 E99 R100 W112 I114L93-A96 PolarHBondContact O-N 3.48Å; L93-A96 VanDerWaalsContact O-N 3.09Å; A96-K98 VanDerWaalsContact C-N 3.33Å; A96-K98 PolarHBondContact O-N 3.37Å; A96-E99 PolarHBondContact O-N 2.91Å; A96-R100 PolarHBondContact O-N 3.01Å; A96-W112 HydrophobicContact CB-CH2 3.88Å; A96-W112 HydrophobicContact CB-CZ2 4.24Å; A96-I114 HydrophobicContact CB-CD1 4.02Å; A96-I114 HydrophobicContact CB-CG2 4.5Å
97L97.3Very high94.7Very high69 Ų6976.2 Ų76.236%0.36133%0.331SS..Hα-helixtrans-61.5-40175.3-73.4167.3000112.2L93 W101 I114L93-L97 HydrophobicContact CB-CD1 4.47Å; L93-L97 WeakPolarHBondContact O-CB 3.43Å; L93-L97 WeakPolarHBondContact O-CG 3.36Å; L93-L97 PolarHBondContact O-N 2.89Å; L97-W101 WeakPolarHBondContact O-CB 3.42Å; L97-W101 PolarHBondContact O-N 2.86Å; L97-I114 HydrophobicContact CD2-CB 3.94Å; L97-I114 HydrophobicContact CD2-CD1 4.26Å; L97-I114 HydrophobicContact CD2-CG2 4Å; L97-I114 HydrophobicContact CG-CG2 4.09Å
98K96.8Very high94.7Very high119 Ų11977.1 Ų77.152%0.51734%0.342SS..Hα-helixtrans-62-48.8175.1-178.7-176.7169.1-171.80111.2K94 Y95 A96 R100 W101 E102K94-K98 WeakPolarHBondContact O-CB 3.36Å; K94-K98 PolarHBondContact O-N 3.09Å; Y95-K98 WeakPolarHBondContact O-CB 3.3Å; Y95-K98 PolarHBondContact O-N 3.32Å; A96-K98 VanDerWaalsContact C-N 3.33Å; A96-K98 PolarHBondContact O-N 3.37Å; K98-R100 PolarHBondContact O-N 2.99Å; K98-W101 WeakPolarHBondContact O-CB 3.37Å; K98-W101 PolarHBondContact O-N 3.29Å; K98-E102 WeakPolarHBondContact CE-OE1 3.34Å; K98-E102 IonicContact NZ-OE1 2.74Å; K98-E102 WeakPolarHBondContact O-CG 3.38Å; K98-E102 PolarHBondContact O-N 2.94Å
99E96.9Very high95Very high59 Ų5976.2 Ų76.228%0.27633%0.334SS..Hα-helixtrans-59.7-48178.2-175.569.6-159.300111.3I74 Y95 A96 W101 E102 R103 F109I74-E99 HydrophobicContact CD1-CB 4.16Å; I74-E99 HydrophobicContact CD1-CG 3.66Å; I74-E99 HydrophobicContact CG1-CG 4.02Å; Y95-E99 PolarHBondContact O-N 3.35Å; A96-E99 PolarHBondContact O-N 2.91Å; E99-W101 VanDerWaalsContact C-N 3.26Å; E99-W101 PolarHBondContact O-N 2.92Å; E99-E102 PolarHBondContact O-N 3.1Å; E99-R103 PolarHBondContact O-N 2.87Å; E99-R103 WeakPolarHBondContact OE1-CD 3.19Å; E99-R103 IonicContact OE1-NH1 3.49Å; E99-F109 HydrophobicContact CG-CE1 4.49Å
100R97.9Very high95.4Very high71 Ų7181.6 Ų81.627%0.26836%0.363SS..Hα-helixtrans-54.9-44.4175.8-172-177.967.3173.9-1111.4A96 K98 R103 R104 F109 W112 I114A96-R100 PolarHBondContact O-N 3.01Å; K98-R100 PolarHBondContact O-N 2.99Å; R100-R103 CarbonylContact O-C 3.49Å; R100-R103 PolarHBondContact O-N 2.84Å; R100-R104 WeakPolarHBondContact O-CA 3.33Å; R100-R104 PolarHBondContact O-N 3.01Å; R100-F109 VanDerWaalsContact CG-O 3.24Å; R100-F109 WeakPolarHBondContact CG-O 3.14Å; R100-W112 HydrophobicContact CB-CE3 3.74Å; R100-W112 HydrophobicContact CB-CZ3 3.91Å; R100-W112 WeakPolarHBondContact CD-O 3Å; R100-W112 HydrophobicContact CG-CE3 3.95Å; R100-W112 PolarHBondContact NH1-O 3.13Å; R100-I114 HydrophobicContact CB-CD1 3.86Å; R100-I114 HydrophobicContact CG-CD1 4.39Å
101W97.8Very high95.9Very high166 Ų16682.4 Ų82.463%0.62936%0.364SS*.Hα-helixtrans-64.7-44.4178.5178.1-101.3000112.4L97 K98 E99 R103 R104L97-W101 WeakPolarHBondContact O-CB 3.42Å; L97-W101 PolarHBondContact O-N 2.86Å; K98-W101 WeakPolarHBondContact O-CB 3.37Å; K98-W101 PolarHBondContact O-N 3.29Å; E99-W101 VanDerWaalsContact C-N 3.26Å; E99-W101 PolarHBondContact O-N 2.92Å; W101-R103 VanDerWaalsContact C-N 3.26Å; W101-R103 PolarHBondContact O-N 2.86Å; W101-R104 WeakPolarHBondContact O-CB 3.39Å; W101-R104 WeakPolarHBondContact O-CD 3.43Å; W101-R104 WeakPolarHBondContact O-CG 3.41Å; W101-R104 PolarHBondContact O-N 2.94Å; W101-R104 PolarHBondContact O-NH1 2.84Å
102E98.1Very high96.4Very high107 Ų10779 Ų7950%0.535%0.349SS..Hα-helixtrans-61.5-37.1179.6-73.8175.6173.100111.4K98 E99K98-E102 WeakPolarHBondContact CE-OE1 3.34Å; K98-E102 IonicContact NZ-OE1 2.74Å; K98-E102 WeakPolarHBondContact O-CG 3.38Å; K98-E102 PolarHBondContact O-N 2.94Å; E99-E102 PolarHBondContact O-N 3.1Å
103R98.1Very high97Very high52 Ų5281.5 Ų81.520%0.19637%0.365CS..THydrogen-bonded Turntrans-99.511.7-179-62.8-177.666.6179-1115E78 E99 R100 W101 K105 E106 F109E78-R103 IonicContact OE1-CZ 3.49Å; E78-R103 IonicContact OE1-NH1 2.94Å; E78-R103 PolarHBondContact OE1-NH1 3.29Å; E78-R103 IonicContact OE1-NH2 3.97Å; E78-R103 PolarHBondContact OE1-NH2 3.32Å; E99-R103 PolarHBondContact O-N 2.87Å; E99-R103 WeakPolarHBondContact OE1-CD 3.19Å; E99-R103 IonicContact OE1-NH1 3.49Å; R100-R103 CarbonylContact O-C 3.49Å; R100-R103 PolarHBondContact O-N 2.84Å; W101-R103 VanDerWaalsContact C-N 3.26Å; W101-R103 PolarHBondContact O-N 2.86Å; R103-K105 PolarHBondContact O-N 2.93Å; R103-E106 IonicContact CZ-OE1 3.89Å; R103-E106 IonicContact CZ-OE2 3.53Å; R103-E106 IonicContact NE-OE1 2.77Å; R103-E106 PolarHBondContact NE-OE1 3.09Å; R103-E106 IonicContact NE-OE2 2.78Å; R103-E106 PolarHBondContact NE-OE2 3.13Å; R103-E106 IonicContact NH2-OE1 3.75Å; R103-E106 PolarHBondContact NH2-OE1 2.48Å; R103-E106 IonicContact NH2-OE2 3.46Å; R103-E106 PolarHBondContact NH2-OE2 3.15Å; R103-E106 WeakPolarHBondContact O-CB 3.32Å; R103-E106 PolarHBondContact O-N 3.36Å; R103-F109 HydrophobicContact CB-CB 4.06Å; R103-F109 HydrophobicContact CB-CD1 3.89Å; R103-F109 HydrophobicContact CB-CD2 4.1Å; R103-F109 HydrophobicContact CB-CE1 4.42Å; R103-F109 HydrophobicContact CB-CG 3.72Å
104R97.8Very high97.3Very high94 Ų9481.4 Ų81.436%0.35536%0.364SS..THydrogen-bonded Turntrans-56.8-11.1-176.873.2-167.5178.4-69.40.4116.3R100 W101 E106R100-R104 WeakPolarHBondContact O-CA 3.33Å; R100-R104 PolarHBondContact O-N 3.01Å; W101-R104 WeakPolarHBondContact O-CB 3.39Å; W101-R104 WeakPolarHBondContact O-CD 3.43Å; W101-R104 WeakPolarHBondContact O-CG 3.41Å; W101-R104 PolarHBondContact O-N 2.94Å; W101-R104 PolarHBondContact O-NH1 2.84Å; R104-E106 VanDerWaalsContact C-N 3.35Å
105K98.3Very high97.5Very high183 Ų18380.1 Ų80.180%0.79636%0.36SS*.THydrogen-bonded Turntrans-82.3-16.7174.1-62.5-56.5-174-177.10112.6R103R103-K105 PolarHBondContact O-N 2.93Å
106E98.4Very high97.7Very high84 Ų8482.9 Ų82.939%0.39338%0.375SS..SBendtrans-82.2120.8169.6-62.6171.6-121.400108.8R103 R104 A108 F109 D110R103-E106 IonicContact CZ-OE1 3.89Å; R103-E106 IonicContact CZ-OE2 3.53Å; R103-E106 IonicContact NE-OE1 2.77Å; R103-E106 PolarHBondContact NE-OE1 3.09Å; R103-E106 IonicContact NE-OE2 2.78Å; R103-E106 PolarHBondContact NE-OE2 3.13Å; R103-E106 IonicContact NH2-OE1 3.75Å; R103-E106 PolarHBondContact NH2-OE1 2.48Å; R103-E106 IonicContact NH2-OE2 3.46Å; R103-E106 PolarHBondContact NH2-OE2 3.15Å; R103-E106 WeakPolarHBondContact O-CB 3.32Å; R103-E106 PolarHBondContact O-N 3.36Å; R104-E106 VanDerWaalsContact C-N 3.35Å; E106-A108 PolarHBondContact O-N 3.29Å; E106-A108 VanDerWaalsContact O-N 3.09Å; E106-F109 HydrophobicContact CB-CB 4.44Å; E106-F109 HydrophobicContact CB-CD2 3.93Å; E106-F109 PolarHBondContact O-N 3.45Å; E106-D110 PolarHBondContact O-N 3.15Å
107R98.1Very high97.7Very high187 Ų18783.1 Ų83.171%0.70638%0.377SS*.Hα-helixtrans-53.3-35.4-177.4178-178.3163.1101-3.3113Q111R107-Q111 WeakPolarHBondContact O-CB 3.3Å; R107-Q111 VanDerWaalsContact O-CG 3.29Å; R107-Q111 WeakPolarHBondContact O-CG 3.17Å; R107-Q111 PolarHBondContact O-N 2.84Å; R107-Q111 VanDerWaalsContact O-N 3.13Å
108A97.9Very high97.6Very high44 Ų4480 Ų8036%0.36436%0.361SS..Hα-helixtrans-64.4-41.6179.100000112V77 E106 Q111 W112V77-A108 HydrophobicContact CG1-CB 3.68Å; E106-A108 PolarHBondContact O-N 3.29Å; E106-A108 VanDerWaalsContact O-N 3.09Å; A108-Q111 PolarHBondContact O-N 3.45Å; A108-W112 PolarHBondContact O-N 3.16Å
109F98.4Very high97.7Very high1 Ų175.6 Ų75.60%0.00434%0.341CS..Hα-helixtrans-75.3-34.9177.7-76.2-94.9000112.5I74 V77 E78 E99 R100 R103 E106 Q111 W112I74-F109 HydrophobicContact CG1-CE1 4.38Å; I74-F109 HydrophobicContact CG2-CE1 4.16Å; I74-F109 HydrophobicContact CG2-CZ 4.05Å; V77-F109 HydrophobicContact CB-CE2 4.48Å; V77-F109 HydrophobicContact CB-CZ 4.28Å; V77-F109 HydrophobicContact CG1-CD1 4.23Å; V77-F109 HydrophobicContact CG1-CD2 3.73Å; V77-F109 HydrophobicContact CG1-CE1 4.18Å; V77-F109 HydrophobicContact CG1-CE2 3.64Å; V77-F109 HydrophobicContact CG1-CG 4Å; V77-F109 HydrophobicContact CG1-CZ 3.86Å; E78-F109 HydrophobicContact CG-CE2 4.09Å; E78-F109 HydrophobicContact CG-CZ 3.96Å; E99-F109 HydrophobicContact CG-CE1 4.49Å; R100-F109 VanDerWaalsContact CG-O 3.24Å; R100-F109 WeakPolarHBondContact CG-O 3.14Å; R103-F109 HydrophobicContact CB-CB 4.06Å; R103-F109 HydrophobicContact CB-CD1 3.89Å; R103-F109 HydrophobicContact CB-CD2 4.1Å; R103-F109 HydrophobicContact CB-CE1 4.42Å; R103-F109 HydrophobicContact CB-CG 3.72Å; E106-F109 HydrophobicContact CB-CB 4.44Å; E106-F109 HydrophobicContact CB-CD2 3.93Å; E106-F109 PolarHBondContact O-N 3.45Å; F109-Q111 PolarHBondContact O-N 3.23Å; F109-W112 AromaticContact CD1-CE3 3.92Å; F109-W112 HydrophobicContact CD1-CE3 3.92Å; F109-W112 HydrophobicContact CD1-CZ3 4.31Å; F109-W112 HydrophobicContact CE1-CE3 4.26Å; F109-W112 HydrophobicContact CE1-CZ3 4.34Å; F109-W112 WeakPolarHBondContact O-CB 3.4Å; F109-W112 PolarHBondContact O-N 3.25Å; F109-W112 VanDerWaalsContact O-N 3.16Å
110D98Very high97.6Very high116 Ų11674 Ų7462%0.6233%0.334SS*.Hα-helixtrans-60.6-32.9172.2-172.563.9000112E106E106-D110 PolarHBondContact O-N 3.15Å
111Q97.9Very high97.6Very high98 Ų9872.6 Ų72.646%0.45833%0.334SS..THydrogen-bonded Turntrans-86.7-6.3177.5-69.2-176-21.900114.3R107 A108 F109 V113R107-Q111 WeakPolarHBondContact O-CB 3.3Å; R107-Q111 VanDerWaalsContact O-CG 3.29Å; R107-Q111 WeakPolarHBondContact O-CG 3.17Å; R107-Q111 PolarHBondContact O-N 2.84Å; R107-Q111 VanDerWaalsContact O-N 3.13Å; A108-Q111 PolarHBondContact O-N 3.45Å; F109-Q111 PolarHBondContact O-N 3.23Å; Q111-V113 PolarHBondContact O-N 3.34Å
112W98.6Very high97.6Very high2 Ų264.7 Ų64.71%0.00830%0.304CS..  trans-73.5118179.9178.222.4000110.5I74 V77 M83 S85 A96 R100 A108 F109 I114I74-W112 HydrophobicContact CD1-CH2 4.42Å; I74-W112 HydrophobicContact CG1-CH2 3.74Å; I74-W112 HydrophobicContact CG1-CZ3 3.84Å; V77-W112 HydrophobicContact CG2-CB 3.99Å; V77-W112 HydrophobicContact CG2-CD2 4Å; V77-W112 HydrophobicContact CG2-CE3 4.46Å; V77-W112 HydrophobicContact CG2-CG 3.77Å; M83-W112 HydrophobicContact CB-CG 4.39Å; S85-W112 PolarHBondContact OG-NE1 2.91Å; A96-W112 HydrophobicContact CB-CH2 3.88Å; A96-W112 HydrophobicContact CB-CZ2 4.24Å; R100-W112 HydrophobicContact CB-CE3 3.74Å; R100-W112 HydrophobicContact CB-CZ3 3.91Å; R100-W112 WeakPolarHBondContact CD-O 3Å; R100-W112 HydrophobicContact CG-CE3 3.95Å; R100-W112 PolarHBondContact NH1-O 3.13Å; A108-W112 PolarHBondContact O-N 3.16Å; F109-W112 AromaticContact CD1-CE3 3.92Å; F109-W112 HydrophobicContact CD1-CE3 3.92Å; F109-W112 HydrophobicContact CD1-CZ3 4.31Å; F109-W112 HydrophobicContact CE1-CE3 4.26Å; F109-W112 HydrophobicContact CE1-CZ3 4.34Å; F109-W112 WeakPolarHBondContact O-CB 3.4Å; F109-W112 PolarHBondContact O-N 3.25Å; F109-W112 VanDerWaalsContact O-N 3.16Å; W112-I114 HydrophobicContact CD2-CD1 3.74Å; W112-I114 HydrophobicContact CD2-CG1 3.82Å; W112-I114 VanDerWaalsContact CE2-CG1 3.44Å; W112-I114 HydrophobicContact CE3-CD1 3.82Å; W112-I114 HydrophobicContact CE3-CG1 4.42Å; W112-I114 HydrophobicContact CG-CG1 4.17Å; W112-I114 HydrophobicContact CH2-CD1 3.59Å; W112-I114 HydrophobicContact CH2-CG1 4.34Å; W112-I114 HydrophobicContact CZ2-CD1 3.5Å; W112-I114 VanDerWaalsContact CZ2-CD1 3.5Å; W112-I114 HydrophobicContact CZ2-CG1 3.73Å; W112-I114 HydrophobicContact CZ3-CD1 3.74Å
113V98.4Very high97.4Very high59 Ų5962.5 Ų62.536%0.35830%0.298SS..EExtended strand (participates in β ladder)trans-88.6129.1178.1-179.40000109.5M83 T84 S85 Q111 E115M83-V113 PolarHBondContact O-N 3.26Å; M83-V113 VanDerWaalsContact O-N 3.15Å; T84-V113 CarbonylContact C-O 3.19Å; T84-V113 WeakPolarHBondContact CA-O 3.41Å; T84-V113 HydrophobicContact CG2-CB 4.16Å; T84-V113 HydrophobicContact CG2-CG1 3.98Å; S85-V113 PolarHBondContact N-O 3.03Å; Q111-V113 PolarHBondContact O-N 3.34Å; V113-E115 HydrophobicContact CG1-CG 3.93Å
114I98.4Very high97.3Very high5 Ų567.8 Ų67.83%0.02633%0.325CS..EExtended strand (participates in β ladder)trans-133.5119.5178.1-54.3173.1000107.6S85 L93 A96 L97 R100 W112S85-I114 VanDerWaalsContact O-CA 3.29Å; S85-I114 WeakPolarHBondContact O-CA 2.84Å; L93-I114 HydrophobicContact CD2-CG2 3.79Å; A96-I114 HydrophobicContact CB-CD1 4.02Å; A96-I114 HydrophobicContact CB-CG2 4.5Å; L97-I114 HydrophobicContact CD2-CB 3.94Å; L97-I114 HydrophobicContact CD2-CD1 4.26Å; L97-I114 HydrophobicContact CD2-CG2 4Å; L97-I114 HydrophobicContact CG-CG2 4.09Å; R100-I114 HydrophobicContact CB-CD1 3.86Å; R100-I114 HydrophobicContact CG-CD1 4.39Å; W112-I114 HydrophobicContact CD2-CD1 3.74Å; W112-I114 HydrophobicContact CD2-CG1 3.82Å; W112-I114 VanDerWaalsContact CE2-CG1 3.44Å; W112-I114 HydrophobicContact CE3-CD1 3.82Å; W112-I114 HydrophobicContact CE3-CG1 4.42Å; W112-I114 HydrophobicContact CG-CG1 4.17Å; W112-I114 HydrophobicContact CH2-CD1 3.59Å; W112-I114 HydrophobicContact CH2-CG1 4.34Å; W112-I114 HydrophobicContact CZ2-CD1 3.5Å; W112-I114 VanDerWaalsContact CZ2-CD1 3.5Å; W112-I114 HydrophobicContact CZ2-CG1 3.73Å; W112-I114 HydrophobicContact CZ3-CD1 3.74Å
115E96.5Very high97.2Very high112 Ų11266.6 Ų66.652%0.52333%0.325SS..EExtended strand (participates in β ladder)trans-138.8162.6-177.1-58.9-61.4157.100111S85 V86 L93 V113S85-E115 PolarHBondContact O-N 3.41Å; S85-E115 VanDerWaalsContact O-N 3.07Å; V86-E115 VanDerWaalsContact CA-O 3.25Å; V86-E115 WeakPolarHBondContact CA-O 3.41Å; V86-E115 HydrophobicContact CG1-CB 4.22Å; L93-E115 WeakPolarHBondContact CD1-O 3.29Å; V113-E115 HydrophobicContact CG1-CG 3.93Å
116E96.4Very high97.1Very high113 Ų11358.5 Ų58.553%0.52829%0.291SS..EExtended strand (participates in β ladder)trans-82.5134.4170.1-170.3-175.4150.300109.9D87 L93D87-E116 WeakPolarHBondContact O-CA 3.29Å; L93-E116 HydrophobicContact CD1-CB 4.18Å
117A95.9Very high96.9Very high5 Ų563 Ų634%0.04131%0.313CS..  trans-155.1155.3171.600000111.7V86 D87 A88 L122 D125 V126V86-A117 HydrophobicContact CB-CB 3.65Å; V86-A117 HydrophobicContact CG1-CB 3.94Å; V86-A117 HydrophobicContact CG2-CB 3.89Å; D87-A117 CarbonylContact C-O 3.57Å; D87-A117 PolarHBondContact O-N 3.41Å; A88-A117 WeakPolarHBondContact CA-O 3.25Å; A88-A117 PolarHBondContact N-O 2.75Å; A117-L122 HydrophobicContact CB-CD1 3.83Å; A117-D125 HydrophobicContact CB-CB 3.56Å; A117-V126 HydrophobicContact CB-CG2 3.77Å
118N94.9Very high96.6Very high4 Ų457.8 Ų57.82%0.02130%0.295CS..  trans-119136.3177.8-177-36.9000110.1S16 V17 L19 L120 T121 L122 D125S16-N118 PolarHBondContact OG-ND2 2.74Å; V17-N118 PolarHBondContact O-ND2 2.82Å; L19-N118 VanDerWaalsContact CB-ND2 3.34Å; L19-N118 WeakPolarHBondContact CB-ND2 3.29Å; N118-L120 PolarHBondContact O-N 3.34Å; N118-L120 VanDerWaalsContact O-N 3.08Å; N118-L120 PolarHBondContact OD1-N 3.02Å; N118-T121 CarbonylContact O-C 3.6Å; N118-T121 PolarHBondContact O-N 3.21Å; N118-T121 PolarHBondContact O-OG1 3.14Å; N118-L122 VanDerWaalsContact O-CA 3.3Å; N118-L122 WeakPolarHBondContact O-CA 3.06Å; N118-L122 WeakPolarHBondContact O-CB 3.35Å; N118-L122 PolarHBondContact O-N 3.49Å; N118-D125 PolarHBondContact N-OD2 3.23Å
119W98.1Very high96.2Very high25 Ų2557.1 Ų57.110%0.09529%0.287CS..THydrogen-bonded Turntrans-57-29.6-178.4-56.3-31000113.7L19 V65 A66 T121 S142 F143 L146 A159 N162 I163L19-W119 HydrophobicContact CD1-CE3 4.18Å; L19-W119 HydrophobicContact CD1-CZ3 4.43Å; V65-W119 PolarHBondContact O-NE1 3.38Å; A66-W119 HydrophobicContact CB-CZ2 4.3Å; W119-T121 VanDerWaalsContact C-N 3.3Å; W119-T121 PolarHBondContact O-N 3.03Å; W119-S142 WeakPolarHBondContact CH2-O 3.38Å; W119-F143 AromaticContact CE3-CD2 3.99Å; W119-F143 HydrophobicContact CE3-CD2 3.99Å; W119-F143 HydrophobicContact CE3-CE2 4.27Å; W119-F143 AromaticContact CZ3-CD2 4Å; W119-F143 HydrophobicContact CZ3-CD2 4Å; W119-L146 HydrophobicContact CE3-CB 4.36Å; W119-L146 HydrophobicContact CZ3-CB 4.18Å; W119-A159 HydrophobicContact CB-CB 3.7Å; W119-N162 VanDerWaalsContact O-CB 3.28Å; W119-N162 WeakPolarHBondContact O-CB 3.3Å; W119-N162 PolarHBondContact O-ND2 2.98Å; W119-I163 HydrophobicContact CB-CD1 4.35Å; W119-I163 HydrophobicContact CD2-CD1 4.3Å; W119-I163 HydrophobicContact CG-CD1 3.97Å; W119-I163 HydrophobicContact CG-CG1 4.46Å
120L96.4Very high95.8Very high25 Ų2560.5 Ų60.513%0.13132%0.322CS..THydrogen-bonded Turntrans-72.2-23.3178.8-58.8178.4000113.1N118 L146 D155 L158 A159 N162N118-L120 PolarHBondContact O-N 3.34Å; N118-L120 VanDerWaalsContact O-N 3.08Å; N118-L120 PolarHBondContact OD1-N 3.02Å; L120-L146 HydrophobicContact CD2-CD2 4.5Å; L120-D155 HydrophobicContact CD2-CB 3.97Å; L120-D155 WeakPolarHBondContact CD2-O 3.26Å; L120-L158 HydrophobicContact CD2-CD2 4.35Å; L120-A159 HydrophobicContact CD2-CB 4.15Å; L120-N162 VanDerWaalsContact C-ND2 3.31Å; L120-N162 PolarHBondContact O-ND2 3.13Å
121T96.9Very high95.4Very high42 Ų4261.6 Ų61.626%0.25833%0.328SS..THydrogen-bonded Turntrans-123.111.2-178.9500000113N118 W119 T123 E124 D125N118-T121 CarbonylContact O-C 3.6Å; N118-T121 PolarHBondContact O-N 3.21Å; N118-T121 PolarHBondContact O-OG1 3.14Å; W119-T121 VanDerWaalsContact C-N 3.3Å; W119-T121 PolarHBondContact O-N 3.03Å; T121-T123 PolarHBondContact O-N 3Å; T121-E124 WeakPolarHBondContact O-CA 3.22Å; T121-E124 WeakPolarHBondContact O-CB 3.49Å; T121-E124 PolarHBondContact O-N 3.25Å; T121-D125 PolarHBondContact O-N 3.05Å; T121-D125 VanDerWaalsContact O-N 3.11Å; T121-D125 PolarHBondContact OG1-OD2 2.68Å
122L97.1Very high95.4Very high0 Ų057 Ų570%031%0.306CS..Hα-helixtrans-53.7-32.1-168.5-166.168.9000113.9V65 V86 A117 N118 E124 D125 V126 N162 I163 M166V65-L122 HydrophobicContact CG1-CD1 4.46Å; V65-L122 HydrophobicContact CG1-CD2 3.94Å; V86-L122 HydrophobicContact CG2-CD1 4.06Å; A117-L122 HydrophobicContact CB-CD1 3.83Å; N118-L122 VanDerWaalsContact O-CA 3.3Å; N118-L122 WeakPolarHBondContact O-CA 3.06Å; N118-L122 WeakPolarHBondContact O-CB 3.35Å; N118-L122 PolarHBondContact O-N 3.49Å; L122-E124 VanDerWaalsContact C-N 3.26Å; L122-E124 PolarHBondContact O-N 2.96Å; L122-D125 PolarHBondContact O-N 3Å; L122-V126 HydrophobicContact CD1-CG2 3.74Å; L122-V126 HydrophobicContact CG-CG2 4.37Å; L122-V126 PolarHBondContact O-N 3.09Å; L122-N162 HydrophobicContact CB-CB 4.11Å; L122-I163 HydrophobicContact CD2-CG1 3.91Å; L122-M166 HydrophobicContact CB-CE 4.44Å; L122-M166 HydrophobicContact CD2-CE 4.41Å; L122-M166 HydrophobicContact CD2-CG 3.8Å; L122-M166 HydrophobicContact CG-CE 4.02Å; L122-M166 HydrophobicContact CG-CG 4.34Å; L122-M166 WeakPolarHBondContact O-CE 3.37Å
123T95.8Very high95.4Very high62 Ų6257.1 Ų57.138%0.3831%0.307SS..Hα-helixtrans-67.4-24.317850.40000114.3T121 N162 S165 M166T121-T123 PolarHBondContact O-N 3Å; T123-N162 HydrophobicContact CG2-CB 4.38Å; T123-S165 WeakPolarHBondContact CG2-OG 3.43Å; T123-M166 VanDerWaalsContact CA-CE 3.48Å; T123-M166 HydrophobicContact CG2-CE 4Å
124E95.7Very high95.4Very high163 Ų16354.9 Ų54.976%0.76229%0.293SS*.Hα-helixtrans-93.1-36.1176.1-59.6175.1-167.400110.4T121 L122T121-E124 WeakPolarHBondContact O-CA 3.22Å; T121-E124 WeakPolarHBondContact O-CB 3.49Å; T121-E124 PolarHBondContact O-N 3.25Å; L122-E124 VanDerWaalsContact C-N 3.26Å; L122-E124 PolarHBondContact O-N 2.96Å
125D94.9Very high95.4Very high68 Ų6854.6 Ų54.636%0.36429%0.292SS..Hα-helixtrans-75.6-34.5-175.9-57.1-24.2000113.1A117 N118 T121 L122A117-D125 HydrophobicContact CB-CB 3.56Å; N118-D125 PolarHBondContact N-OD2 3.23Å; T121-D125 PolarHBondContact O-N 3.05Å; T121-D125 VanDerWaalsContact O-N 3.11Å; T121-D125 PolarHBondContact OG1-OD2 2.68Å; L122-D125 PolarHBondContact O-N 3Å
126V96.3Very high95.5Very high13 Ų1349.3 Ų49.38%0.07927%0.267CS..SBendtrans-119120.6-171.5-175.40000111.9L63 V86 A117 L122 K128 F133 M166L63-V126 HydrophobicContact CD1-CG1 4.17Å; L63-V126 HydrophobicContact CD2-CG1 4.47Å; V86-V126 HydrophobicContact CG1-CG2 3.82Å; V86-V126 HydrophobicContact CG2-CG2 4.38Å; A117-V126 HydrophobicContact CB-CG2 3.77Å; L122-V126 HydrophobicContact CD1-CG2 3.74Å; L122-V126 HydrophobicContact CG-CG2 4.37Å; L122-V126 PolarHBondContact O-N 3.09Å; V126-K128 PolarHBondContact O-N 2.8Å; V126-F133 HydrophobicContact CG1-CE2 4.27Å; V126-F133 HydrophobicContact CG1-CZ 4.35Å; V126-M166 HydrophobicContact CB-CE 4.45Å
127Q93.9Very high95.6Very high180 Ų18044 Ų4484%0.84124%0.242SC*.  trans-72.5121.6174.4-170.5175.85.800111.6
128K91.6Very high95.8Very high76 Ų7643.7 Ų43.733%0.3324%0.24SC..  trans-72.3130.9176.8-65.5178.5-172.3-1760111.3V126 G130 S165 M166V126-K128 PolarHBondContact O-N 2.8Å; K128-G130 PolarHBondContact O-N 3.49Å; K128-S165 WeakPolarHBondContact CE-O 3.41Å; K128-S165 PolarHBondContact NZ-O 3.42Å; K128-S165 PolarHBondContact NZ-OG 2.83Å; K128-M166 HydrophobicContact CD-SD 4.08Å; K128-M166 VanDerWaalsContact CE-CE 3.42Å; K128-M166 WeakPolarHBondContact CE-SD 3.43Å; K128-M166 HydrophobicContact CG-CE 4.25Å; K128-M166 HydrophobicContact CG-SD 3.57Å; K128-M166 VanDerWaalsContact CG-SD 3.57Å
129P89.8Confident95.9Very high31 Ų3143.9 Ų43.920%0.20124%0.241CC..SBendtrans-75.4106.1170.228.7-31.2000110N131 G132 F133P129-N131 PolarHBondContact O-N 2.96Å; P129-N131 VanDerWaalsContact O-N 3.15Å; P129-G132 PolarHBondContact O-N 3.28Å; P129-F133 VanDerWaalsContact CD-CE2 3.41Å; P129-F133 HydrophobicContact CG-CD1 4.01Å; P129-F133 HydrophobicContact CG-CD2 4.21Å; P129-F133 HydrophobicContact CG-CE1 3.96Å; P129-F133 HydrophobicContact CG-CE2 4.16Å; P129-F133 HydrophobicContact CG-CG 4.14Å; P129-F133 HydrophobicContact CG-CZ 4.03Å
130G90.3Very high95.6Very high71 Ų7142.9 Ų42.973%0.73224%0.238SC*.THydrogen-bonded Turntrans58.6-118-177.500000111.4K128 G132K128-G130 PolarHBondContact O-N 3.49Å; G130-G132 VanDerWaalsContact C-N 3.33Å
131N90.3Very high95.6Very high139 Ų13941.9 Ų41.974%0.74323%0.233SC*.THydrogen-bonded Turntrans-88.58.3-180-64.1-17.2000114.1P129 R168P129-N131 PolarHBondContact O-N 2.96Å; P129-N131 VanDerWaalsContact O-N 3.15Å; N131-R168 WeakPolarHBondContact O-CA 3.22Å; N131-R168 WeakPolarHBondContact O-CB 3.4Å
132G96.8Very high95.6Very high1 Ų141 Ų411%0.0123%0.229CC..  trans124.8-178.5178.600000113.9P129 G130 M166P129-G132 PolarHBondContact O-N 3.28Å; G130-G132 VanDerWaalsContact C-N 3.33Å; G132-M166 CarbonylContact C-O 3.49Å; G132-M166 WeakPolarHBondContact CA-O 3.43Å
133F98.7Very high95.7Very high6 Ų641 Ų413%0.02623%0.229CC..EExtended strand (participates in β ladder)trans-81.3149.2178.5-66.6-94.5000111.7R61 L63 T84 V126 P129 A135 V136 M166 R168R61-F133 HydrophobicContact CB-CD1 4.29Å; L63-F133 HydrophobicContact CB-CB 4.27Å; L63-F133 HydrophobicContact CB-CD1 3.72Å; L63-F133 HydrophobicContact CB-CD2 3.7Å; L63-F133 HydrophobicContact CB-CE1 3.89Å; L63-F133 HydrophobicContact CB-CE2 3.87Å; L63-F133 HydrophobicContact CB-CG 3.62Å; L63-F133 HydrophobicContact CB-CZ 3.96Å; L63-F133 HydrophobicContact CD1-CE2 4.34Å; L63-F133 HydrophobicContact CD1-CZ 4.13Å; L63-F133 HydrophobicContact CD2-CD2 4.03Å; L63-F133 HydrophobicContact CD2-CE2 3.87Å; L63-F133 HydrophobicContact CD2-CZ 4.47Å; L63-F133 HydrophobicContact CG-CD2 4.43Å; L63-F133 HydrophobicContact CG-CE2 4.25Å; L63-F133 HydrophobicContact CG-CZ 4.41Å; T84-F133 HydrophobicContact CG2-CZ 4.39Å; V126-F133 HydrophobicContact CG1-CE2 4.27Å; V126-F133 HydrophobicContact CG1-CZ 4.35Å; P129-F133 VanDerWaalsContact CD-CE2 3.41Å; P129-F133 HydrophobicContact CG-CD1 4.01Å; P129-F133 HydrophobicContact CG-CD2 4.21Å; P129-F133 HydrophobicContact CG-CE1 3.96Å; P129-F133 HydrophobicContact CG-CE2 4.16Å; P129-F133 HydrophobicContact CG-CG 4.14Å; P129-F133 HydrophobicContact CG-CZ 4.03Å; F133-A135 VanDerWaalsContact C-N 3.31Å; F133-A135 WeakPolarHBondContact CB-O 3.22Å; F133-V136 HydrophobicContact CB-CG2 4.22Å; F133-M166 HydrophobicContact CD2-CB 4.33Å; F133-M166 PolarHBondContact N-O 3.35Å; F133-R168 WeakPolarHBondContact O-CG 3.29Å; F133-R168 PolarHBondContact O-N 3Å
134D98.6Very high95.7Very high11 Ų1138.1 Ų38.16%0.05921%0.211CC..EExtended strand (participates in β ladder)trans-67.7-36.8176.5-57.3-55.5000110.9V59 Q60 R61 R168 G171 I172V59-D134 HydrophobicContact CB-CB 4.18Å; V59-D134 HydrophobicContact CG1-CB 3.95Å; V59-D134 HydrophobicContact CG2-CB 4.12Å; Q60-D134 PolarHBondContact N-OD2 3.15Å; Q60-D134 VanDerWaalsContact N-OD2 3.13Å; R61-D134 PolarHBondContact N-OD2 3.24Å; R61-D134 IonicContact NE-OD2 3.9Å; R61-D134 WeakPolarHBondContact O-CB 3.49Å; R61-D134 PolarHBondContact O-N 2.86Å; D134-R168 IonicContact OD1-CZ 3.34Å; D134-R168 IonicContact OD1-NE 2.67Å; D134-R168 PolarHBondContact OD1-NE 3.36Å; D134-R168 IonicContact OD1-NH2 3.12Å; D134-R168 PolarHBondContact OD1-NH2 3.23Å; D134-R168 VanDerWaalsContact OD1-NH2 3.12Å; D134-G171 CarbonylContact O-C 3.59Å; D134-G171 WeakPolarHBondContact O-CA 3.29Å; D134-I172 PolarHBondContact O-N 3.07Å
135A98.8Very high95.7Very high0 Ų031.6 Ų31.60%018%0.18CC..EExtended strand (participates in β ladder)trans-136.7150.3168.100000112.1L54 V59 R61 I62 L63 F133 I172L54-A135 HydrophobicContact CD2-CB 3.64Å; V59-A135 HydrophobicContact CG1-CB 3.84Å; V59-A135 HydrophobicContact CG2-CB 3.96Å; R61-A135 PolarHBondContact O-N 2.85Å; I62-A135 VanDerWaalsContact CA-O 3.31Å; I62-A135 WeakPolarHBondContact CA-O 3.37Å; I62-A135 HydrophobicContact CG1-CB 4.31Å; I62-A135 HydrophobicContact CG2-CB 4.44Å; L63-A135 PolarHBondContact N-O 3.31Å; F133-A135 VanDerWaalsContact C-N 3.31Å; F133-A135 WeakPolarHBondContact CB-O 3.22Å; A135-I172 CarbonylContact C-O 3.56Å; A135-I172 WeakPolarHBondContact CA-O 3.48Å; A135-I172 HydrophobicContact CB-CD1 4.43Å; A135-I172 HydrophobicContact CB-CG1 3.73Å
136V98.9Very high95.7Very high0 Ų028.4 Ų28.40%016%0.163CC..EExtended strand (participates in β ladder)trans-121137166.5-176.70000107.5L63 V65 F133 I163 M166 V167 I172 L173 I174L63-V136 HydrophobicContact CB-CG1 4.38Å; L63-V136 HydrophobicContact CB-CG2 4.23Å; L63-V136 HydrophobicContact CD2-CG1 4.36Å; L63-V136 HydrophobicContact CG-CG1 4.47Å; L63-V136 CarbonylContact O-C 3.49Å; L63-V136 VanDerWaalsContact O-CA 3.26Å; L63-V136 WeakPolarHBondContact O-CA 3.21Å; V65-V136 HydrophobicContact CG1-CG1 3.81Å; V65-V136 HydrophobicContact CG2-CG1 4.43Å; F133-V136 HydrophobicContact CB-CG2 4.22Å; V136-I163 HydrophobicContact CG1-CG2 3.93Å; V136-M166 HydrophobicContact CG2-CB 3.85Å; V136-V167 HydrophobicContact CB-CG2 3.95Å; V136-V167 HydrophobicContact CG2-CB 4.38Å; V136-V167 HydrophobicContact CG2-CG2 3.54Å; V136-I172 PolarHBondContact N-O 3.32Å; V136-L173 HydrophobicContact CB-CD1 3.94Å; V136-L173 HydrophobicContact CG1-CD1 3.97Å; V136-L173 CarbonylContact O-C 3.58Å; V136-L173 VanDerWaalsContact O-CA 3.32Å; V136-L173 WeakPolarHBondContact O-CA 3.28Å; V136-L173 WeakPolarHBondContact O-CD1 3.41Å; V136-I174 PolarHBondContact O-N 3.29Å
137I98.9Very high95.6Very high1 Ų128.8 Ų28.81%0.00517%0.166CC..EExtended strand (participates in β ladder)trans-124.5141.8179.568.5175.2000111.3I62 L63 D64 V65 L76 I174I62-I137 HydrophobicContact CG2-CD1 4.33Å; I62-I137 HydrophobicContact CG2-CG1 4.23Å; I62-I137 HydrophobicContact CG2-CG2 4.11Å; L63-I137 PolarHBondContact O-N 2.92Å; D64-I137 HydrophobicContact CB-CD1 4.04Å; D64-I137 HydrophobicContact CB-CG1 3.79Å; V65-I137 WeakPolarHBondContact CG2-O 3.44Å; V65-I137 PolarHBondContact N-O 3.24Å; L76-I137 HydrophobicContact CD1-CD1 3.65Å; I137-I174 CarbonylContact C-O 3.56Å; I137-I174 VanDerWaalsContact CA-O 3.29Å; I137-I174 WeakPolarHBondContact CA-O 3.25Å; I137-I174 HydrophobicContact CG2-CB 4.19Å; I137-I174 HydrophobicContact CG2-CD1 4.24Å; I137-I174 HydrophobicContact CG2-CG1 4.39Å
138C98.6Very high95.5Very high0 Ų020.6 Ų20.60%013%0.128CC..EExtended strand (participates in β ladder)trans-14585.1173.4-174.90000107.9V65 I174 I175 D176V65-C138 HydrophobicContact CG2-CB 3.61Å; C138-I174 PolarHBondContact N-O 2.76Å; C138-I175 HydrophobicContact CB-CB 4.19Å; C138-I175 HydrophobicContact CB-CD1 4Å; C138-I175 HydrophobicContact CB-CG1 3.84Å; C138-I175 VanDerWaalsContact O-CA 3.29Å; C138-I175 WeakPolarHBondContact O-CA 3.36Å; C138-D176 PolarHBondContact O-N 3.16Å; C138-D176 VanDerWaalsContact O-N 3.1Å
139L97.2Very high95.3Very high7 Ų722.3 Ų22.34%0.03714%0.136CC..  trans-107.2168.5-172.5-61.1-179000112S142 I174 D176 Y196L139-S142 PolarHBondContact O-OG 3.44Å; L139-I174 HydrophobicContact CD2-CG2 3.85Å; L139-D176 VanDerWaalsContact CA-OD1 3.25Å; L139-D176 WeakPolarHBondContact CA-OD1 3.34Å; L139-D176 HydrophobicContact CD2-CB 4.32Å; L139-Y196 HydrophobicContact CB-CE1 4.41Å
140G93.3Very high95.3Very high4 Ų427 Ų274%0.04115%0.153CC..SBendtrans83.824.9174.700000113.9S142 D176G140-S142 PolarHBondContact O-N 2.85Å; G140-D176 VanDerWaalsContact N-CG 3.3Å; G140-D176 PolarHBondContact N-OD1 2.85Å; G140-D176 PolarHBondContact N-OD2 3.14Å
141N95.9Very high95.3Very high5 Ų526.2 Ų26.23%0.02715%0.145CC..SBendtrans60.524.3-175.7174.670.2000113.1F143 A144 D176 R178 Y180 Y244 Y285N141-F143 PolarHBondContact O-N 2.92Å; N141-A144 PolarHBondContact O-N 3.41Å; N141-A144 WeakPolarHBondContact OD1-CB 3.35Å; N141-D176 WeakPolarHBondContact CA-OD1 3.45Å; N141-D176 PolarHBondContact N-OD1 3.03Å; N141-D176 PolarHBondContact N-OD2 3.2Å; N141-R178 HydrophobicContact CB-CB 4.38Å; N141-R178 PolarHBondContact OD1-N 3.28Å; N141-Y180 VanDerWaalsContact CG-OH 3.29Å; N141-Y180 PolarHBondContact ND2-OH 2.85Å; N141-Y180 WeakPolarHBondContact OD1-CE2 3.43Å; N141-Y180 PolarHBondContact OD1-OH 3.18Å; N141-Y244 WeakPolarHBondContact ND2-CD1 3.31Å; N141-Y244 WeakPolarHBondContact ND2-CE1 3.47Å; N141-Y285 HydrophobicContact CB-CD1 4.2Å; N141-Y285 HydrophobicContact CB-CE1 3.7Å
142S96.6Very high95.5Very high24 Ų2423.7 Ų23.717%0.16813%0.132CC..G310 helixtrans-63.4-42.1-173.4-63.20000112.1A66 W119 L139 G140 A144 H145A66-S142 VanDerWaalsContact CB-CB 3.48Å; W119-S142 WeakPolarHBondContact CH2-O 3.38Å; L139-S142 PolarHBondContact O-OG 3.44Å; G140-S142 PolarHBondContact O-N 2.85Å; S142-A144 PolarHBondContact O-N 2.9Å; S142-A144 VanDerWaalsContact O-N 3.11Å; S142-H145 VanDerWaalsContact O-CB 3.31Å; S142-H145 WeakPolarHBondContact O-CB 3.29Å; S142-H145 PolarHBondContact O-CD2 3.42Å; S142-H145 VanDerWaalsContact O-CD2 3.31Å; S142-H145 PolarHBondContact O-N 3.2Å
143F98.2Very high95.4Very high0 Ų024.4 Ų24.40%014%0.135CC..G310 helixtrans-58.3-31-177.5-171.1-94.9000113.4W119 N141 H145 L146 Q156 A159 L160 I163 I175 H247 F252W119-F143 AromaticContact CE3-CD2 3.99Å; W119-F143 HydrophobicContact CE3-CD2 3.99Å; W119-F143 HydrophobicContact CE3-CE2 4.27Å; W119-F143 AromaticContact CZ3-CD2 4Å; W119-F143 HydrophobicContact CZ3-CD2 4Å; N141-F143 PolarHBondContact O-N 2.92Å; F143-H145 PolarHBondContact O-N 3.44Å; F143-L146 HydrophobicContact CE2-CD2 4.35Å; F143-L146 HydrophobicContact CZ-CD2 4.23Å; F143-L146 PolarHBondContact O-N 2.93Å; F143-L146 VanDerWaalsContact O-N 3.09Å; F143-Q156 HydrophobicContact CE1-CB 4.25Å; F143-Q156 HydrophobicContact CE1-CG 4.42Å; F143-Q156 HydrophobicContact CZ-CB 4.07Å; F143-Q156 HydrophobicContact CZ-CG 4.46Å; F143-A159 HydrophobicContact CE2-CB 3.85Å; F143-A159 HydrophobicContact CZ-CB 4.27Å; F143-L160 HydrophobicContact CD2-CD2 4.04Å; F143-L160 HydrophobicContact CE1-CD1 4.31Å; F143-L160 HydrophobicContact CE1-CD2 4.15Å; F143-L160 HydrophobicContact CE1-CG 4.14Å; F143-L160 HydrophobicContact CE2-CD2 3.55Å; F143-L160 HydrophobicContact CE2-CG 3.81Å; F143-L160 HydrophobicContact CZ-CD1 4.07Å; F143-L160 HydrophobicContact CZ-CD2 3.63Å; F143-L160 HydrophobicContact CZ-CG 3.47Å; F143-L160 VanDerWaalsContact CZ-CG 3.47Å; F143-I163 HydrophobicContact CD2-CD1 4.24Å; F143-I163 HydrophobicContact CE2-CD1 4.26Å; F143-I175 HydrophobicContact CB-CD1 3.99Å; F143-I175 HydrophobicContact CB-CG1 4.47Å; F143-I175 HydrophobicContact CD2-CD1 4.1Å; F143-I175 HydrophobicContact CG-CD1 4.02Å; F143-H247 AromaticContact CD1-NE2 3.59Å; F143-H247 AromaticContact CE1-CE1 3.82Å; F143-H247 AromaticContact CE1-NE2 3.68Å; F143-F252 AromaticContact CD1-CE2 3.52Å; F143-F252 HydrophobicContact CD1-CE2 3.52Å; F143-F252 HydrophobicContact CD1-CZ 4.09Å; F143-F252 AromaticContact CE1-CE2 3.83Å; F143-F252 HydrophobicContact CE1-CE2 3.83Å; F143-F252 HydrophobicContact CG-CE2 4.39Å
144A97.3Very high95.4Very high0 Ų025.8 Ų25.80%015%0.145CC..G310 helixtrans-64.6-11.7178.100000113.4N141 S142 L146 Y180 Y244 Y245N141-A144 PolarHBondContact O-N 3.41Å; N141-A144 WeakPolarHBondContact OD1-CB 3.35Å; S142-A144 PolarHBondContact O-N 2.9Å; S142-A144 VanDerWaalsContact O-N 3.11Å; A144-L146 PolarHBondContact O-N 2.88Å; A144-Y180 HydrophobicContact CB-CE2 3.81Å; A144-Y180 VanDerWaalsContact CB-OH 3.24Å; A144-Y180 WeakPolarHBondContact CB-OH 3.45Å; A144-Y244 HydrophobicContact CB-CD1 4.07Å; A144-Y244 CarbonylContact O-C 3.56Å; A144-Y244 VanDerWaalsContact O-CA 3.26Å; A144-Y244 WeakPolarHBondContact O-CA 3.37Å; A144-Y245 PolarHBondContact O-N 2.83Å
145H95.1Very high95.3Very high26 Ų2626.4 Ų26.412%0.1215%0.148CC..G310 helixtrans-69.2-19172.6-77.8-74.9000113.8Q22 Y23 S142 F143 P147 Y244Q22-H145 PolarHBondContact NE2-ND1 3.01Å; Q22-H145 VanDerWaalsContact NE2-ND1 3.16Å; Y23-H145 PolarHBondContact OH-CE1 2.99Å; Y23-H145 VanDerWaalsContact OH-CE1 3.29Å; Y23-H145 PolarHBondContact OH-NE2 3.09Å; S142-H145 VanDerWaalsContact O-CB 3.31Å; S142-H145 WeakPolarHBondContact O-CB 3.29Å; S142-H145 PolarHBondContact O-CD2 3.42Å; S142-H145 VanDerWaalsContact O-CD2 3.31Å; S142-H145 PolarHBondContact O-N 3.2Å; F143-H145 PolarHBondContact O-N 3.44Å; H145-P147 WeakPolarHBondContact O-CD 3.48Å; H145-Y244 AromaticContact CD2-CE1 3.92Å; H145-Y244 AromaticContact CE1-CD1 3.97Å; H145-Y244 AromaticContact CE1-CE1 3.27Å; H145-Y244 WeakPolarHBondContact CE1-CE1 3.47Å; H145-Y244 AromaticContact CE1-CZ 3.74Å; H145-Y244 AromaticContact ND1-CE1 3.9Å; H145-Y244 AromaticContact NE2-CE1 3.24Å; H145-Y244 WeakPolarHBondContact NE2-CE1 3.4Å; H145-Y244 AromaticContact NE2-CZ 3.97Å
146L95.2Very high95.2Very high1 Ų126.5 Ų26.51%0.00515%0.149CC..SBendtrans-78108.1177.7176.263.6000110.1L19 W119 L120 F143 A144 D155 Q156 A159L19-L146 HydrophobicContact CD1-CB 4.26Å; L19-L146 HydrophobicContact CD1-CD1 3.71Å; L19-L146 HydrophobicContact CD1-CG 4.48Å; W119-L146 HydrophobicContact CE3-CB 4.36Å; W119-L146 HydrophobicContact CZ3-CB 4.18Å; L120-L146 HydrophobicContact CD2-CD2 4.5Å; F143-L146 HydrophobicContact CE2-CD2 4.35Å; F143-L146 HydrophobicContact CZ-CD2 4.23Å; F143-L146 PolarHBondContact O-N 2.93Å; F143-L146 VanDerWaalsContact O-N 3.09Å; A144-L146 PolarHBondContact O-N 2.88Å; L146-D155 HydrophobicContact CD1-CB 4.44Å; L146-Q156 HydrophobicContact CD2-CB 4.28Å; L146-Q156 HydrophobicContact CD2-CG 3.82Å; L146-Q156 HydrophobicContact CG-CG 3.93Å; L146-Q156 PolarHBondContact O-NE2 3.2Å; L146-A159 HydrophobicContact CD2-CB 3.55Å
147P92.8Very high95.2Very high21 Ų2130.7 Ų30.714%0.13617%0.167CC..  trans-75161.9-177.433.6-36.4000111.6H145 F149H145-P147 WeakPolarHBondContact O-CD 3.48Å; P147-F149 HydrophobicContact CB-CD1 4.37Å; P147-F149 HydrophobicContact CB-CD2 4.44Å; P147-F149 HydrophobicContact CB-CE1 3.99Å; P147-F149 HydrophobicContact CB-CE2 4.09Å; P147-F149 HydrophobicContact CB-CZ 3.84Å; P147-F149 HydrophobicContact CG-CD1 4.44Å; P147-F149 HydrophobicContact CG-CD2 3.76Å; P147-F149 HydrophobicContact CG-CE1 3.94Å; P147-F149 HydrophobicContact CG-CE2 3.18Å; P147-F149 HydrophobicContact CG-CG 4.35Å; P147-F149 HydrophobicContact CG-CZ 3.27Å
148D92.9Very high95.2Very high9 Ų933.9 Ų33.95%0.04818%0.183CC..  trans-103.980.5171.3-177.615000110.3K150 G151 D152 Q153 H217 Y245D148-K150 VanDerWaalsContact C-N 3.25Å; D148-K150 PolarHBondContact O-N 3.48Å; D148-G151 WeakPolarHBondContact OD1-CA 2.8Å; D148-G151 PolarHBondContact OD1-N 3.45Å; D148-G151 VanDerWaalsContact OD2-CA 3.25Å; D148-G151 WeakPolarHBondContact OD2-CA 3.39Å; D148-D152 PolarHBondContact OD1-N 3.43Å; D148-D152 PolarHBondContact OD2-N 2.79Å; D148-Q153 PolarHBondContact OD1-N 2.82Å; D148-Q153 VanDerWaalsContact OD1-N 3.15Å; D148-Q153 PolarHBondContact OD2-N 2.93Å; D148-H217 PolarHBondContact O-CE1 3Å; D148-Y245 HydrophobicContact CB-CD2 3.68Å; D148-Y245 HydrophobicContact CB-CE2 3.42Å; D148-Y245 VanDerWaalsContact CB-CE2 3.42Å
149F86.6Confident95.2Very high111 Ų11133.9 Ų33.949%0.48718%0.183SC..SBendtrans-72-19.7179.7-66.2-53.2000113.7P20 P147P20-F149 HydrophobicContact CG-CE2 3.76Å; P20-F149 HydrophobicContact CG-CZ 3.95Å; P147-F149 HydrophobicContact CB-CD1 4.37Å; P147-F149 HydrophobicContact CB-CD2 4.44Å; P147-F149 HydrophobicContact CB-CE1 3.99Å; P147-F149 HydrophobicContact CB-CE2 4.09Å; P147-F149 HydrophobicContact CB-CZ 3.84Å; P147-F149 HydrophobicContact CG-CD1 4.44Å; P147-F149 HydrophobicContact CG-CD2 3.76Å; P147-F149 HydrophobicContact CG-CE1 3.94Å; P147-F149 HydrophobicContact CG-CE2 3.18Å; P147-F149 HydrophobicContact CG-CG 4.35Å; P147-F149 HydrophobicContact CG-CZ 3.27Å
150K90.7Very high95.3Very high130 Ų13033.5 Ų33.557%0.56518%0.182SC*.SBendtrans-92.7-22.8-176.8-67.6165.7179.3170.40112.4D148 D152 S154 D155D148-K150 VanDerWaalsContact C-N 3.25Å; D148-K150 PolarHBondContact O-N 3.48Å; K150-D152 WeakPolarHBondContact CB-OD1 3.41Å; K150-S154 WeakPolarHBondContact CD-OG 3.22Å; K150-S154 PolarHBondContact NZ-OG 3.3Å; K150-D155 IonicContact NZ-OD1 2.75Å; K150-D155 PolarHBondContact NZ-OD1 2.94Å; K150-D155 IonicContact NZ-OD2 3.69Å; K150-D155 PolarHBondContact NZ-OD2 2.99Å
151G90.6Very high95.5Very high55 Ų5537.4 Ų37.457%0.56720%0.199SC*.SBendtrans84.7817900000114.5D148D148-G151 WeakPolarHBondContact OD1-CA 2.8Å; D148-G151 PolarHBondContact OD1-N 3.45Å; D148-G151 VanDerWaalsContact OD2-CA 3.25Å; D148-G151 WeakPolarHBondContact OD2-CA 3.39Å
152D93.9Very high95.6Very high86 Ų8638 Ų3846%0.4620%0.202SC..SBendtrans-123.13.2-176.869.9-4.9000113.8D148 K150 S154 K157D148-D152 PolarHBondContact OD1-N 3.43Å; D148-D152 PolarHBondContact OD2-N 2.79Å; K150-D152 WeakPolarHBondContact CB-OD1 3.41Å; D152-S154 PolarHBondContact O-N 3.49Å; D152-S154 VanDerWaalsContact OD1-CB 3.22Å; D152-S154 WeakPolarHBondContact OD1-CB 3.34Å; D152-S154 PolarHBondContact OD1-N 2.83Å; D152-S154 PolarHBondContact OD1-OG 3.11Å; D152-K157 PolarHBondContact O-NZ 2.79Å
153Q95.8Very high95.7Very high16 Ų1636.9 Ų36.98%0.07519%0.194CC..  trans59.122-175-52.5-174-48.300114.2D148 D155 Q156 K157 Y245 N251D148-Q153 PolarHBondContact OD1-N 2.82Å; D148-Q153 VanDerWaalsContact OD1-N 3.15Å; D148-Q153 PolarHBondContact OD2-N 2.93Å; Q153-D155 VanDerWaalsContact C-N 3.29Å; Q153-D155 PolarHBondContact O-N 3.36Å; Q153-Q156 HydrophobicContact CB-CB 4.37Å; Q153-Q156 PolarHBondContact O-N 3.1Å; Q153-K157 WeakPolarHBondContact O-CG 3.4Å; Q153-K157 PolarHBondContact O-N 3.49Å; Q153-Y245 PolarHBondContact NE2-OH 3.16Å; Q153-N251 PolarHBondContact NE2-OD1 3.21Å; Q153-N251 PolarHBondContact OE1-ND2 3.38Å; Q153-N251 PolarHBondContact OE1-OD1 3.02Å
154S97Very high95.8Very high35 Ų3537 Ų3725%0.24520%0.195CC..Hα-helixtrans-59-42.1-17576.80000112.2K150 D152 K157 L158K150-S154 WeakPolarHBondContact CD-OG 3.22Å; K150-S154 PolarHBondContact NZ-OG 3.3Å; D152-S154 PolarHBondContact O-N 3.49Å; D152-S154 VanDerWaalsContact OD1-CB 3.22Å; D152-S154 WeakPolarHBondContact OD1-CB 3.34Å; D152-S154 PolarHBondContact OD1-N 2.83Å; D152-S154 PolarHBondContact OD1-OG 3.11Å; S154-K157 PolarHBondContact O-N 2.76Å; S154-L158 WeakPolarHBondContact O-CB 3.37Å; S154-L158 PolarHBondContact O-N 3.11Å
155D96.3Very high95.8Very high24 Ų2438.5 Ų38.513%0.12821%0.206CC..Hα-helixtrans-71.3-35.2-177.1-66.6-13.6000111L120 L146 K150 Q153 L158 A159L120-D155 HydrophobicContact CD2-CB 3.97Å; L120-D155 WeakPolarHBondContact CD2-O 3.26Å; L146-D155 HydrophobicContact CD1-CB 4.44Å; K150-D155 IonicContact NZ-OD1 2.75Å; K150-D155 PolarHBondContact NZ-OD1 2.94Å; K150-D155 IonicContact NZ-OD2 3.69Å; K150-D155 PolarHBondContact NZ-OD2 2.99Å; Q153-D155 VanDerWaalsContact C-N 3.29Å; Q153-D155 PolarHBondContact O-N 3.36Å; D155-L158 PolarHBondContact O-N 3.34Å; D155-A159 VanDerWaalsContact O-CB 3.26Å; D155-A159 WeakPolarHBondContact O-CB 3.32Å; D155-A159 PolarHBondContact O-N 2.86Å
156Q98.1Very high96Very high1 Ų137.3 Ų37.31%0.00520%0.2CC..Hα-helixtrans-67.9-43174.9-65.9155-15.700111.2F143 L146 Q153 A159 L160F143-Q156 HydrophobicContact CE1-CB 4.25Å; F143-Q156 HydrophobicContact CE1-CG 4.42Å; F143-Q156 HydrophobicContact CZ-CB 4.07Å; F143-Q156 HydrophobicContact CZ-CG 4.46Å; L146-Q156 HydrophobicContact CD2-CB 4.28Å; L146-Q156 HydrophobicContact CD2-CG 3.82Å; L146-Q156 HydrophobicContact CG-CG 3.93Å; L146-Q156 PolarHBondContact O-NE2 3.2Å; Q153-Q156 HydrophobicContact CB-CB 4.37Å; Q153-Q156 PolarHBondContact O-N 3.1Å; Q156-A159 PolarHBondContact O-N 2.78Å; Q156-L160 WeakPolarHBondContact O-CG 3.24Å; Q156-L160 PolarHBondContact O-N 2.96Å
157K98.6Very high96.1Very high88 Ų8837.2 Ų37.238%0.38320%0.2SC..Hα-helixtrans-61.6-44.9173.9-71.7163.5-178.2157.50111.3D152 Q153 S154 L160 Q161 I255D152-K157 PolarHBondContact O-NZ 2.79Å; Q153-K157 WeakPolarHBondContact O-CG 3.4Å; Q153-K157 PolarHBondContact O-N 3.49Å; S154-K157 PolarHBondContact O-N 2.76Å; K157-L160 PolarHBondContact O-N 3.4Å; K157-Q161 WeakPolarHBondContact O-CB 3.41Å; K157-Q161 VanDerWaalsContact O-CG 3.24Å; K157-Q161 WeakPolarHBondContact O-CG 3.31Å; K157-Q161 PolarHBondContact O-N 3.45Å; K157-I255 HydrophobicContact CG-CB 4.42Å; K157-I255 HydrophobicContact CG-CG2 4.26Å
158L98.3Very high96.4Very high68 Ų6839.5 Ų39.536%0.35621%0.206SC..Hα-helixtrans-61.7-47.2176.4177.160.9000111.8L120 S154 D155 L160 Q161 N162L120-L158 HydrophobicContact CD2-CD2 4.35Å; S154-L158 WeakPolarHBondContact O-CB 3.37Å; S154-L158 PolarHBondContact O-N 3.11Å; D155-L158 PolarHBondContact O-N 3.34Å; L158-L160 PolarHBondContact O-N 3.42Å; L158-Q161 WeakPolarHBondContact O-CB 3.48Å; L158-Q161 PolarHBondContact O-N 2.75Å; L158-N162 PolarHBondContact O-N 2.89Å
159A98.6Very high96.6Very high0 Ų041.7 Ų41.70%022%0.22CC..Hα-helixtrans-57.9-46.9176.800000111.7W119 L120 F143 L146 D155 Q156 Q161 N162 I163W119-A159 HydrophobicContact CB-CB 3.7Å; L120-A159 HydrophobicContact CD2-CB 4.15Å; F143-A159 HydrophobicContact CE2-CB 3.85Å; F143-A159 HydrophobicContact CZ-CB 4.27Å; L146-A159 HydrophobicContact CD2-CB 3.55Å; D155-A159 VanDerWaalsContact O-CB 3.26Å; D155-A159 WeakPolarHBondContact O-CB 3.32Å; D155-A159 PolarHBondContact O-N 2.86Å; Q156-A159 PolarHBondContact O-N 2.78Å; A159-Q161 PolarHBondContact O-N 3.26Å; A159-N162 PolarHBondContact O-N 2.79Å; A159-I163 WeakPolarHBondContact O-CB 3.3Å; A159-I163 VanDerWaalsContact O-CG1 3.24Å; A159-I163 WeakPolarHBondContact O-CG1 3.28Å; A159-I163 PolarHBondContact O-N 2.81Å
160L98.8Very high97.1Very high0 Ų038 Ų380%021%0.213CC..Hα-helixtrans-64.7-38.5176.5-70.1177.6000112.4F143 Q156 K157 L158 I163 A164 I175 I255 L256 A259F143-L160 HydrophobicContact CD2-CD2 4.04Å; F143-L160 HydrophobicContact CE1-CD1 4.31Å; F143-L160 HydrophobicContact CE1-CD2 4.15Å; F143-L160 HydrophobicContact CE1-CG 4.14Å; F143-L160 HydrophobicContact CE2-CD2 3.55Å; F143-L160 HydrophobicContact CE2-CG 3.81Å; F143-L160 HydrophobicContact CZ-CD1 4.07Å; F143-L160 HydrophobicContact CZ-CD2 3.63Å; F143-L160 HydrophobicContact CZ-CG 3.47Å; F143-L160 VanDerWaalsContact CZ-CG 3.47Å; Q156-L160 WeakPolarHBondContact O-CG 3.24Å; Q156-L160 PolarHBondContact O-N 2.96Å; K157-L160 PolarHBondContact O-N 3.4Å; L158-L160 PolarHBondContact O-N 3.42Å; L160-I163 PolarHBondContact O-N 3.15Å; L160-A164 WeakPolarHBondContact O-CB 3.44Å; L160-A164 PolarHBondContact O-N 3.26Å; L160-I175 HydrophobicContact CD2-CD1 3.81Å; L160-I255 HydrophobicContact CD1-CB 4.22Å; L160-I255 HydrophobicContact CD1-CD1 3.67Å; L160-I255 HydrophobicContact CD1-CG1 3.58Å; L160-L256 HydrophobicContact CD1-CD1 4.24Å; L160-L256 HydrophobicContact CD2-CD1 3.77Å; L160-L256 HydrophobicContact CG-CD1 4.46Å; L160-A259 HydrophobicContact CB-CB 3.74Å
161Q98.7Very high97.5Very high85 Ų8531.9 Ų31.940%0.39719%0.187SC..Hα-helixtrans-61-45.7174.5-77170.4-15.500111.2K157 L158 A159 A164 S165 A259K157-Q161 WeakPolarHBondContact O-CB 3.41Å; K157-Q161 VanDerWaalsContact O-CG 3.24Å; K157-Q161 WeakPolarHBondContact O-CG 3.31Å; K157-Q161 PolarHBondContact O-N 3.45Å; L158-Q161 WeakPolarHBondContact O-CB 3.48Å; L158-Q161 PolarHBondContact O-N 2.75Å; A159-Q161 PolarHBondContact O-N 3.26Å; Q161-A164 PolarHBondContact O-N 2.97Å; Q161-S165 WeakPolarHBondContact O-CB 3.49Å; Q161-S165 PolarHBondContact O-N 3.15Å; Q161-A259 HydrophobicContact CG-CB 4.27Å
162N98.6Very high97.9Very high19 Ų1929.2 Ų29.210%0.10216%0.16CC..Hα-helixtrans-62.7-46.4177.3-75.2-15.6000111.7W119 L120 L122 T123 L158 A159 S165 M166W119-N162 VanDerWaalsContact O-CB 3.28Å; W119-N162 WeakPolarHBondContact O-CB 3.3Å; W119-N162 PolarHBondContact O-ND2 2.98Å; L120-N162 VanDerWaalsContact C-ND2 3.31Å; L120-N162 PolarHBondContact O-ND2 3.13Å; L122-N162 HydrophobicContact CB-CB 4.11Å; T123-N162 HydrophobicContact CG2-CB 4.38Å; L158-N162 PolarHBondContact O-N 2.89Å; A159-N162 PolarHBondContact O-N 2.79Å; N162-S165 WeakPolarHBondContact O-CB 3.43Å; N162-S165 PolarHBondContact O-N 2.65Å; N162-S165 PolarHBondContact O-OG 3Å; N162-M166 PolarHBondContact O-N 3.07Å
163I98.8Very high98.1Very high0 Ų025.1 Ų25.10%014%0.138CC..Hα-helixtrans-60.1-49.6175.2-68.5166.5000110.8V65 W119 L122 V136 F143 A159 L160 S165 M166 L173V65-I163 HydrophobicContact CG2-CD1 4.15Å; V65-I163 HydrophobicContact CG2-CG1 4.25Å; V65-I163 HydrophobicContact CG2-CG2 4.49Å; W119-I163 HydrophobicContact CB-CD1 4.35Å; W119-I163 HydrophobicContact CD2-CD1 4.3Å; W119-I163 HydrophobicContact CG-CD1 3.97Å; W119-I163 HydrophobicContact CG-CG1 4.46Å; L122-I163 HydrophobicContact CD2-CG1 3.91Å; V136-I163 HydrophobicContact CG1-CG2 3.93Å; F143-I163 HydrophobicContact CD2-CD1 4.24Å; F143-I163 HydrophobicContact CE2-CD1 4.26Å; A159-I163 WeakPolarHBondContact O-CB 3.3Å; A159-I163 VanDerWaalsContact O-CG1 3.24Å; A159-I163 WeakPolarHBondContact O-CG1 3.28Å; A159-I163 PolarHBondContact O-N 2.81Å; L160-I163 PolarHBondContact O-N 3.15Å; I163-S165 PolarHBondContact O-N 2.63Å; I163-M166 VanDerWaalsContact O-CB 3.32Å; I163-M166 WeakPolarHBondContact O-CB 3.48Å; I163-M166 PolarHBondContact O-N 2.84Å; I163-L173 HydrophobicContact CG2-CD1 3.73Å; I163-L173 HydrophobicContact CG2-CD2 4.12Å
164A98.6Very high98.2Very high2 Ų224.4 Ų24.42%0.01713%0.134CC..Hα-helixtrans-62.3-29.117800000112.5L160 Q161 M166 V167 A259 F260 K292L160-A164 WeakPolarHBondContact O-CB 3.44Å; L160-A164 PolarHBondContact O-N 3.26Å; Q161-A164 PolarHBondContact O-N 2.97Å; A164-M166 PolarHBondContact O-N 3.25Å; A164-V167 PolarHBondContact O-N 2.94Å; A164-A259 HydrophobicContact CB-CB 4.03Å; A164-F260 HydrophobicContact CB-CD1 4.19Å; A164-F260 HydrophobicContact CB-CD2 3.94Å; A164-F260 HydrophobicContact CB-CE1 3.89Å; A164-F260 HydrophobicContact CB-CE2 3.61Å; A164-F260 HydrophobicContact CB-CG 4.22Å; A164-F260 HydrophobicContact CB-CZ 3.59Å; A164-K292 PolarHBondContact O-NZ 2.64Å
165S97.9Very high98.3Very high32 Ų3222.7 Ų22.722%0.22412%0.123CC..Hα-helixtrans-68.7-21175.291.60000113.2T123 K128 Q161 N162 I163 V167T123-S165 WeakPolarHBondContact CG2-OG 3.43Å; K128-S165 WeakPolarHBondContact CE-O 3.41Å; K128-S165 PolarHBondContact NZ-O 3.42Å; K128-S165 PolarHBondContact NZ-OG 2.83Å; Q161-S165 WeakPolarHBondContact O-CB 3.49Å; Q161-S165 PolarHBondContact O-N 3.15Å; N162-S165 WeakPolarHBondContact O-CB 3.43Å; N162-S165 PolarHBondContact O-N 2.65Å; N162-S165 PolarHBondContact O-OG 3Å; I163-S165 PolarHBondContact O-N 2.63Å; S165-V167 VanDerWaalsContact C-N 3.35Å
166M98.6Very high98.4Very high0 Ų021.6 Ų21.60%012%0.117CC..Hα-helixtrans-79-21176.6-63.9-64.6158.300112.2L63 L122 T123 V126 K128 G132 F133 V136 N162 I163 A164L63-M166 HydrophobicContact CD2-CB 3.74Å; L63-M166 HydrophobicContact CD2-CG 3.71Å; L63-M166 HydrophobicContact CD2-SD 4.28Å; L122-M166 HydrophobicContact CB-CE 4.44Å; L122-M166 HydrophobicContact CD2-CE 4.41Å; L122-M166 HydrophobicContact CD2-CG 3.8Å; L122-M166 HydrophobicContact CG-CE 4.02Å; L122-M166 HydrophobicContact CG-CG 4.34Å; L122-M166 WeakPolarHBondContact O-CE 3.37Å; T123-M166 VanDerWaalsContact CA-CE 3.48Å; T123-M166 HydrophobicContact CG2-CE 4Å; V126-M166 HydrophobicContact CB-CE 4.45Å; K128-M166 HydrophobicContact CD-SD 4.08Å; K128-M166 VanDerWaalsContact CE-CE 3.42Å; K128-M166 WeakPolarHBondContact CE-SD 3.43Å; K128-M166 HydrophobicContact CG-CE 4.25Å; K128-M166 HydrophobicContact CG-SD 3.57Å; K128-M166 VanDerWaalsContact CG-SD 3.57Å; G132-M166 CarbonylContact C-O 3.49Å; G132-M166 WeakPolarHBondContact CA-O 3.43Å; F133-M166 HydrophobicContact CD2-CB 4.33Å; F133-M166 PolarHBondContact N-O 3.35Å; V136-M166 HydrophobicContact CG2-CB 3.85Å; N162-M166 PolarHBondContact O-N 3.07Å; I163-M166 VanDerWaalsContact O-CB 3.32Å; I163-M166 WeakPolarHBondContact O-CB 3.48Å; I163-M166 PolarHBondContact O-N 2.84Å; A164-M166 PolarHBondContact O-N 3.25Å
167V98.6Very high98.4Very high0 Ų021.5 Ų21.50%012%0.116CC..EExtended strand (participates in β ladder)trans-76.8125.5176.6-170.30000109.5V136 A164 S165 L173 F260 K292V136-V167 HydrophobicContact CB-CG2 3.95Å; V136-V167 HydrophobicContact CG2-CB 4.38Å; V136-V167 HydrophobicContact CG2-CG2 3.54Å; A164-V167 PolarHBondContact O-N 2.94Å; S165-V167 VanDerWaalsContact C-N 3.35Å; V167-L173 HydrophobicContact CG2-CB 4.02Å; V167-F260 HydrophobicContact CB-CE1 4.29Å; V167-F260 HydrophobicContact CG2-CE1 4.26Å; V167-F260 HydrophobicContact CG2-CZ 4.19Å; V167-K292 HydrophobicContact CB-CD 4.23Å; V167-K292 HydrophobicContact CG1-CB 4.06Å; V167-K292 HydrophobicContact CG1-CD 4.33Å; V167-K292 VanDerWaalsContact O-CD 3.29Å; V167-K292 WeakPolarHBondContact O-CD 3.4Å; V167-K292 PolarHBondContact O-NZ 3.16Å
168R98Very high98.2Very high69 Ų6917.8 Ų17.826%0.2610%0.1SC..EExtended strand (participates in β ladder)trans-68.916017474.7169.3172.980-1.8111.8N131 F133 D134 G170 G171N131-R168 WeakPolarHBondContact O-CA 3.22Å; N131-R168 WeakPolarHBondContact O-CB 3.4Å; F133-R168 WeakPolarHBondContact O-CG 3.29Å; F133-R168 PolarHBondContact O-N 3Å; D134-R168 IonicContact OD1-CZ 3.34Å; D134-R168 IonicContact OD1-NE 2.67Å; D134-R168 PolarHBondContact OD1-NE 3.36Å; D134-R168 IonicContact OD1-NH2 3.12Å; D134-R168 PolarHBondContact OD1-NH2 3.23Å; D134-R168 VanDerWaalsContact OD1-NH2 3.12Å; R168-G170 PolarHBondContact O-N 2.93Å; R168-G171 WeakPolarHBondContact O-CA 3.44Å; R168-G171 PolarHBondContact O-N 3.26Å
169P97.5Very high98.1Very high55 Ų5515 Ų1536%0.3579%0.085SC..EExtended strand (participates in β ladder)trans-54.2129.4166-24.434.9000111.3G171 A294P169-G171 PolarHBondContact O-N 3.43Å; P169-A294 WeakPolarHBondContact CG-OXT 3.26Å
170G97.6Very high97.9Very high32 Ų3215 Ų1533%0.339%0.085SC..EExtended strand (participates in β ladder)trans78.2-2.8-173.600000115.4R168 K292R168-G170 PolarHBondContact O-N 2.93Å; G170-K292 WeakPolarHBondContact CA-O 3.35Å; G170-K292 PolarHBondContact N-O 2.71Å
171G98.4Very high97.8Very high2 Ų216.6 Ų16.62%0.0219%0.094CC..EExtended strand (participates in β ladder)trans-82.5174.9174.100000112.8D134 R168 P169 K291 K292D134-G171 CarbonylContact O-C 3.59Å; D134-G171 WeakPolarHBondContact O-CA 3.29Å; R168-G171 WeakPolarHBondContact O-CA 3.44Å; R168-G171 PolarHBondContact O-N 3.26Å; P169-G171 PolarHBondContact O-N 3.43Å; G171-K291 WeakPolarHBondContact O-CA 3.46Å; G171-K292 PolarHBondContact O-N 3.28Å
172I98.8Very high97.5Very high0 Ų016.4 Ų16.40%09%0.09CC..EExtended strand (participates in β ladder)trans-123.1148-177.264.6175.8000113L53 L54 H57 V59 D134 A135 V136 I174 V290 K291L53-I172 HydrophobicContact CD2-CD1 4.47Å; L53-I172 HydrophobicContact CG-CD1 4.29Å; L54-I172 HydrophobicContact CD2-CD1 4.27Å; H57-I172 HydrophobicContact CB-CD1 4.33Å; V59-I172 HydrophobicContact CG2-CD1 4.45Å; V59-I172 HydrophobicContact CG2-CG1 4.49Å; D134-I172 PolarHBondContact O-N 3.07Å; A135-I172 CarbonylContact C-O 3.56Å; A135-I172 WeakPolarHBondContact CA-O 3.48Å; A135-I172 HydrophobicContact CB-CD1 4.43Å; A135-I172 HydrophobicContact CB-CG1 3.73Å; V136-I172 PolarHBondContact N-O 3.32Å; I172-I174 HydrophobicContact CD1-CD1 4.27Å; I172-I174 HydrophobicContact CD1-CG1 4.31Å; I172-V290 CarbonylContact C-O 3.51Å; I172-V290 WeakPolarHBondContact CA-O 3.48Å; I172-K291 HydrophobicContact CG2-CB 3.95Å; I172-K291 HydrophobicContact CG2-CG 4.1Å
173L98.9Very high97.3Very high0 Ų015.5 Ų15.50%09%0.085CC..EExtended strand (participates in β ladder)trans-108.8131.4163.9171.163.1000108.5V136 I163 V167 I175 L256 F260 V289 V290V136-L173 HydrophobicContact CB-CD1 3.94Å; V136-L173 HydrophobicContact CG1-CD1 3.97Å; V136-L173 CarbonylContact O-C 3.58Å; V136-L173 VanDerWaalsContact O-CA 3.32Å; V136-L173 WeakPolarHBondContact O-CA 3.28Å; V136-L173 WeakPolarHBondContact O-CD1 3.41Å; I163-L173 HydrophobicContact CG2-CD1 3.73Å; I163-L173 HydrophobicContact CG2-CD2 4.12Å; V167-L173 HydrophobicContact CG2-CB 4.02Å; L173-I175 HydrophobicContact CD1-CB 4.21Å; L173-I175 HydrophobicContact CD1-CG2 4.5Å; L173-I175 HydrophobicContact CD2-CG2 3.99Å; L173-I175 HydrophobicContact CG-CB 4.21Å; L173-I175 HydrophobicContact CG-CG2 3.96Å; L173-L256 HydrophobicContact CD2-CD1 3.8Å; L173-F260 HydrophobicContact CB-CZ 3.94Å; L173-F260 HydrophobicContact CD2-CE2 3.85Å; L173-F260 HydrophobicContact CD2-CZ 3.89Å; L173-V289 WeakPolarHBondContact O-CA 3.31Å; L173-V290 HydrophobicContact CB-CB 4.38Å; L173-V290 PolarHBondContact N-O 2.99Å; L173-V290 PolarHBondContact O-N 2.89Å
174I98.8Very high97.1Very high0 Ų016.3 Ų16.30%09%0.09CC..EExtended strand (participates in β ladder)trans-115.2108.9169.7-45.5175.7000107.4W49 L53 L54 V136 I137 C138 L139 I172 I287 H288 V289W49-I174 HydrophobicContact CZ3-CG2 4.34Å; L53-I174 HydrophobicContact CD2-CD1 3.82Å; L53-I174 HydrophobicContact CD2-CG1 4.33Å; L54-I174 HydrophobicContact CD2-CD1 4.2Å; V136-I174 PolarHBondContact O-N 3.29Å; I137-I174 CarbonylContact C-O 3.56Å; I137-I174 VanDerWaalsContact CA-O 3.29Å; I137-I174 WeakPolarHBondContact CA-O 3.25Å; I137-I174 HydrophobicContact CG2-CB 4.19Å; I137-I174 HydrophobicContact CG2-CD1 4.24Å; I137-I174 HydrophobicContact CG2-CG1 4.39Å; C138-I174 PolarHBondContact N-O 2.76Å; L139-I174 HydrophobicContact CD2-CG2 3.85Å; I172-I174 HydrophobicContact CD1-CD1 4.27Å; I172-I174 HydrophobicContact CD1-CG1 4.31Å; I174-I287 HydrophobicContact CG2-CG2 3.74Å; I174-H288 WeakPolarHBondContact CA-O 3.21Å; I174-V289 HydrophobicContact CG2-CG2 4.42Å
175I98.8Very high96.9Very high0 Ų024.2 Ų24.20%013%0.126CC..EExtended strand (participates in β ladder)trans-133.5138.3-177.6-177.9164.2000110C138 F143 L160 L173 F252 L256 H288C138-I175 HydrophobicContact CB-CB 4.19Å; C138-I175 HydrophobicContact CB-CD1 4Å; C138-I175 HydrophobicContact CB-CG1 3.84Å; C138-I175 VanDerWaalsContact O-CA 3.29Å; C138-I175 WeakPolarHBondContact O-CA 3.36Å; F143-I175 HydrophobicContact CB-CD1 3.99Å; F143-I175 HydrophobicContact CB-CG1 4.47Å; F143-I175 HydrophobicContact CD2-CD1 4.1Å; F143-I175 HydrophobicContact CG-CD1 4.02Å; L160-I175 HydrophobicContact CD2-CD1 3.81Å; L173-I175 HydrophobicContact CD1-CB 4.21Å; L173-I175 HydrophobicContact CD1-CG2 4.5Å; L173-I175 HydrophobicContact CD2-CG2 3.99Å; L173-I175 HydrophobicContact CG-CB 4.21Å; L173-I175 HydrophobicContact CG-CG2 3.96Å; I175-F252 HydrophobicContact CD1-CZ 3.91Å; I175-F252 HydrophobicContact CG1-CE1 4.41Å; I175-F252 HydrophobicContact CG1-CZ 4.03Å; I175-F252 HydrophobicContact CG2-CE1 4.23Å; I175-L256 HydrophobicContact CG2-CD1 4.03Å; I175-L256 HydrophobicContact CG2-CD2 3.59Å; I175-L256 HydrophobicContact CG2-CG 4.49Å; I175-H288 HydrophobicContact CG2-CB 3.98Å; I175-H288 PolarHBondContact N-O 3.23Å; I175-H288 WeakPolarHBondContact O-CA 3.28Å; I175-H288 WeakPolarHBondContact O-CB 3.34Å; I175-H288 PolarHBondContact O-N 2.82Å
176D98.4Very high96.6Very high0 Ų025.3 Ų25.30%013%0.132CC..EExtended strand (participates in β ladder)trans-122.4165-178.479.1-18.2000113.3C138 L139 G140 N141 Y196 F286 I287C138-D176 PolarHBondContact O-N 3.16Å; C138-D176 VanDerWaalsContact O-N 3.1Å; L139-D176 VanDerWaalsContact CA-OD1 3.25Å; L139-D176 WeakPolarHBondContact CA-OD1 3.34Å; L139-D176 HydrophobicContact CD2-CB 4.32Å; G140-D176 VanDerWaalsContact N-CG 3.3Å; G140-D176 PolarHBondContact N-OD1 2.85Å; G140-D176 PolarHBondContact N-OD2 3.14Å; N141-D176 WeakPolarHBondContact CA-OD1 3.45Å; N141-D176 PolarHBondContact N-OD1 3.03Å; N141-D176 PolarHBondContact N-OD2 3.2Å; D176-Y196 WeakPolarHBondContact OD2-CE2 3.4Å; D176-Y196 PolarHBondContact OD2-OH 3.04Å; D176-F286 CarbonylContact C-O 3.59Å; D176-F286 WeakPolarHBondContact CA-O 3.3Å; D176-F286 VanDerWaalsContact CB-O 3.3Å; D176-F286 WeakPolarHBondContact CB-O 3.36Å; D176-I287 HydrophobicContact CB-CG1 4.14Å
177H97.6Very high96.1Very high0 Ų027 Ų270%015%0.149CC..EExtended strand (participates in β ladder)trans-149158.9163.765.890.4000109.8Y180 H247 F252 Y285 F286 H288H177-Y180 HydrophobicContact CB-CE2 4.39Å; H177-H247 PolarHBondContact CE1-O 2.97Å; H177-H247 PolarHBondContact ND1-O 3.34Å; H177-F252 AromaticContact CD2-CD1 3.33Å; H177-F252 WeakPolarHBondContact CD2-CD1 3.34Å; H177-F252 AromaticContact CD2-CE1 3.71Å; H177-F252 AromaticContact CD2-CG 3.58Å; H177-F252 AromaticContact NE2-CD1 3.65Å; H177-F252 AromaticContact NE2-CG 3.73Å; H177-Y285 WeakPolarHBondContact O-CA 3.42Å; H177-F286 AromaticContact CE1-CD2 3.71Å; H177-F286 PolarHBondContact N-O 3.23Å; H177-F286 PolarHBondContact O-N 3.1Å; H177-H288 AromaticContact CD2-CD2 3.85Å; H177-H288 AromaticContact CD2-NE2 3.52Å; H177-H288 AromaticContact NE2-NE2 3.19Å; H177-H288 PolarHBondContact NE2-NE2 2.77Å; H177-H288 VanDerWaalsContact NE2-NE2 3.19Å
178R94.6Very high95.5Very high10 Ų1034.6 Ų34.64%0.03818%0.178CC..EExtended strand (participates in β ladder)trans-65.5155174.1-152.5169.2-170.9-1703.9109.9N141 Y180 I183 C284 Y285N141-R178 HydrophobicContact CB-CB 4.38Å; N141-R178 PolarHBondContact OD1-N 3.28Å; R178-Y180 HydrophobicContact CB-CD2 4.49Å; R178-Y180 HydrophobicContact CB-CE1 4.24Å; R178-Y180 HydrophobicContact CB-CE2 4.07Å; R178-Y180 VanDerWaalsContact O-CD2 3.22Å; R178-Y180 WeakPolarHBondContact O-CD2 3.46Å; R178-Y180 PolarHBondContact O-N 2.85Å; R178-I183 HydrophobicContact CG-CD1 4.13Å; R178-C284 VanDerWaalsContact CG-O 3.29Å; R178-C284 WeakPolarHBondContact CG-O 3.45Å; R178-Y285 HydrophobicContact CB-CD1 4.48Å; R178-Y285 HydrophobicContact CB-CE1 4.37Å; R178-Y285 HydrophobicContact CG-CE1 4.3Å
179N94.9Very high94.5Very high8 Ų831.8 Ų31.84%0.04317%0.169CC..  trans-70.979.8173.9-174.7-9.4000110.9D181 Y182 I183 P283 C284 F286N179-D181 VanDerWaalsContact C-N 3.29Å; N179-Y182 PolarHBondContact O-N 3.28Å; N179-Y182 PolarHBondContact OD1-N 2.78Å; N179-I183 WeakPolarHBondContact O-CG1 3.29Å; N179-I183 PolarHBondContact O-N 3.22Å; N179-P283 WeakPolarHBondContact CB-O 3.34Å; N179-P283 PolarHBondContact ND2-O 3.46Å; N179-C284 PolarHBondContact N-O 3.44Å; N179-F286 HydrophobicContact CB-CD2 4.24Å; N179-F286 HydrophobicContact CB-CE2 3.85Å; N179-F286 HydrophobicContact CB-CZ 4.49Å; N179-F286 VanDerWaalsContact CG-CE2 3.46Å; N179-F286 WeakPolarHBondContact OD1-CE2 3.48Å
180Y96.1Very high93.2Very high0 Ų029.9 Ų29.90%016%0.157CC..Hα-helixtrans-72.1-23.7179.6-67.3-65.1000112.6N141 A144 H177 R178 Y182 I183 L184 I219 Y244 P246 H247N141-Y180 VanDerWaalsContact CG-OH 3.29Å; N141-Y180 PolarHBondContact ND2-OH 2.85Å; N141-Y180 WeakPolarHBondContact OD1-CE2 3.43Å; N141-Y180 PolarHBondContact OD1-OH 3.18Å; A144-Y180 HydrophobicContact CB-CE2 3.81Å; A144-Y180 VanDerWaalsContact CB-OH 3.24Å; A144-Y180 WeakPolarHBondContact CB-OH 3.45Å; H177-Y180 HydrophobicContact CB-CE2 4.39Å; R178-Y180 HydrophobicContact CB-CD2 4.49Å; R178-Y180 HydrophobicContact CB-CE1 4.24Å; R178-Y180 HydrophobicContact CB-CE2 4.07Å; R178-Y180 VanDerWaalsContact O-CD2 3.22Å; R178-Y180 WeakPolarHBondContact O-CD2 3.46Å; R178-Y180 PolarHBondContact O-N 2.85Å; Y180-Y182 VanDerWaalsContact C-N 3.32Å; Y180-Y182 PolarHBondContact O-N 3.35Å; Y180-I183 HydrophobicContact CD1-CD1 3.84Å; Y180-I183 HydrophobicContact CE1-CD1 4.17Å; Y180-I183 PolarHBondContact O-N 3.49Å; Y180-L184 VanDerWaalsContact O-CB 3.31Å; Y180-L184 WeakPolarHBondContact O-CB 3.39Å; Y180-L184 WeakPolarHBondContact O-CG 3.07Å; Y180-L184 PolarHBondContact O-N 2.68Å; Y180-I219 HydrophobicContact CD1-CD1 3.41Å; Y180-I219 VanDerWaalsContact CD1-CD1 3.41Å; Y180-I219 HydrophobicContact CE1-CD1 3.95Å; Y180-I219 HydrophobicContact CG-CD1 4.36Å; Y180-Y244 VanDerWaalsContact OH-CB 3.26Å; Y180-Y244 WeakPolarHBondContact OH-CB 3.29Å; Y180-P246 HydrophobicContact CD1-CB 4.3Å; Y180-P246 HydrophobicContact CG-CB 4.24Å; Y180-H247 HydrophobicContact CD2-CB 4.23Å; Y180-H247 VanDerWaalsContact CD2-N 3.33Å; Y180-H247 WeakPolarHBondContact CD2-O 3.42Å
181D95.1Very high91.5Very high34 Ų3436.5 Ų36.518%0.18218%0.179CC..Hα-helixtrans-55.9-48.6170.6-66.1-79.3000110.8N179 L184 E185 R248 I249N179-D181 VanDerWaalsContact C-N 3.29Å; D181-L184 PolarHBondContact O-N 3.25Å; D181-E185 WeakPolarHBondContact O-CB 3.4Å; D181-E185 PolarHBondContact O-N 2.9Å; D181-E185 VanDerWaalsContact O-N 3.1Å; D181-R248 WeakPolarHBondContact OD1-CB 3.39Å; D181-R248 VanDerWaalsContact OD1-CG 3.3Å; D181-R248 WeakPolarHBondContact OD1-CG 3.07Å; D181-R248 IonicContact OD1-CZ 2.68Å; D181-R248 IonicContact OD1-NH1 3.54Å; D181-R248 PolarHBondContact OD1-NH1 3.45Å; D181-R248 WeakPolarHBondContact OD2-CA 3.17Å; D181-I249 PolarHBondContact OD2-N 2.85Å
182Y93.1Very high89.5Confident81 Ų8138.5 Ų38.532%0.31820%0.2SC..Hα-helixtrans-62.5-43174.1-179-82.4000112.7N179 Y180 L184 E185 T186 P190 A282N179-Y182 PolarHBondContact O-N 3.28Å; N179-Y182 PolarHBondContact OD1-N 2.78Å; Y180-Y182 VanDerWaalsContact C-N 3.32Å; Y180-Y182 PolarHBondContact O-N 3.35Å; Y182-L184 PolarHBondContact O-N 2.89Å; Y182-E185 PolarHBondContact O-N 2.98Å; Y182-T186 HydrophobicContact CD1-CG2 4.2Å; Y182-T186 HydrophobicContact CD2-CG2 4.24Å; Y182-T186 HydrophobicContact CE1-CG2 3.87Å; Y182-T186 VanDerWaalsContact CE1-OG1 3.29Å; Y182-T186 WeakPolarHBondContact CE1-OG1 3.14Å; Y182-T186 HydrophobicContact CE2-CG2 3.92Å; Y182-T186 HydrophobicContact CG-CG2 4.37Å; Y182-T186 WeakPolarHBondContact O-CB 3.35Å; Y182-T186 WeakPolarHBondContact O-CG2 3.28Å; Y182-T186 PolarHBondContact O-N 2.99Å; Y182-T186 PolarHBondContact O-OG1 2.82Å; Y182-P190 HydrophobicContact CD1-CB 4.31Å; Y182-P190 HydrophobicContact CD1-CG 3.62Å; Y182-P190 HydrophobicContact CE1-CB 4.22Å; Y182-P190 HydrophobicContact CE1-CG 4.01Å; Y182-P190 HydrophobicContact CG-CG 4.26Å; Y182-A282 HydrophobicContact CD2-CB 3.88Å; Y182-A282 HydrophobicContact CE2-CB 4.39Å
183I93.7Very high87.8Confident0 Ų045.5 Ų45.50%023%0.23CC..Hα-helixtrans-66.1-41-177.6-61.6173.3000111R178 N179 Y180 E185 G187 T207 I219R178-I183 HydrophobicContact CG-CD1 4.13Å; N179-I183 WeakPolarHBondContact O-CG1 3.29Å; N179-I183 PolarHBondContact O-N 3.22Å; Y180-I183 HydrophobicContact CD1-CD1 3.84Å; Y180-I183 HydrophobicContact CE1-CD1 4.17Å; Y180-I183 PolarHBondContact O-N 3.49Å; I183-E185 VanDerWaalsContact C-N 3.33Å; I183-G187 WeakPolarHBondContact O-CA 3.24Å; I183-G187 PolarHBondContact O-N 3.49Å; I183-T207 HydrophobicContact CG2-CG2 3.81Å; I183-I219 HydrophobicContact CB-CD1 4.12Å; I183-I219 HydrophobicContact CG2-CD1 3.67Å; I183-I219 HydrophobicContact CG2-CG2 4.4Å
184L95.1Very high86.5Confident18 Ų1846.4 Ų46.49%0.09424%0.235CC..Hα-helixtrans-68.4-34.1178.5-70175.4000112.1Y180 D181 Y182 V209 W211 P216 I219 P246 R248Y180-L184 VanDerWaalsContact O-CB 3.31Å; Y180-L184 WeakPolarHBondContact O-CB 3.39Å; Y180-L184 WeakPolarHBondContact O-CG 3.07Å; Y180-L184 PolarHBondContact O-N 2.68Å; D181-L184 PolarHBondContact O-N 3.25Å; Y182-L184 PolarHBondContact O-N 2.89Å; L184-V209 HydrophobicContact CD2-CG1 3.73Å; L184-W211 HydrophobicContact CD2-CZ2 4.35Å; L184-P216 HydrophobicContact CD1-CB 3.93Å; L184-P216 HydrophobicContact CD1-CG 3.78Å; L184-P216 HydrophobicContact CD2-CB 3.48Å; L184-P216 VanDerWaalsContact CD2-CB 3.48Å; L184-P216 HydrophobicContact CD2-CG 4.27Å; L184-P216 HydrophobicContact CG-CB 4.36Å; L184-I219 HydrophobicContact CD2-CD1 4.03Å; L184-I219 HydrophobicContact CD2-CG1 4.48Å; L184-I219 HydrophobicContact CG-CD1 4.38Å; L184-P246 HydrophobicContact CD1-CB 4.18Å; L184-P246 HydrophobicContact CD2-CB 4.22Å; L184-P246 HydrophobicContact CG-CB 4.39Å; L184-R248 HydrophobicContact CD1-CG 4.26Å
185E93.6Very high85.4Confident167 Ų16747 Ų4778%0.7824%0.238SC*.Hα-helixtrans-73.7-42.5177.1-175.5175.7-171.500112.4D181 Y182 I183D181-E185 WeakPolarHBondContact O-CB 3.4Å; D181-E185 PolarHBondContact O-N 2.9Å; D181-E185 VanDerWaalsContact O-N 3.1Å; Y182-E185 PolarHBondContact O-N 2.98Å; I183-E185 VanDerWaalsContact C-N 3.33Å
186T91.7Very high84.1Confident56 Ų5647 Ų4734%0.34424%0.238SC..Hα-helixtrans-98.2-13.6-171.864.40000114.2Y182 R188Y182-T186 HydrophobicContact CD1-CG2 4.2Å; Y182-T186 HydrophobicContact CD2-CG2 4.24Å; Y182-T186 HydrophobicContact CE1-CG2 3.87Å; Y182-T186 VanDerWaalsContact CE1-OG1 3.29Å; Y182-T186 WeakPolarHBondContact CE1-OG1 3.14Å; Y182-T186 HydrophobicContact CE2-CG2 3.92Å; Y182-T186 HydrophobicContact CG-CG2 4.37Å; Y182-T186 WeakPolarHBondContact O-CB 3.35Å; Y182-T186 WeakPolarHBondContact O-CG2 3.28Å; Y182-T186 PolarHBondContact O-N 2.99Å; Y182-T186 PolarHBondContact O-OG1 2.82Å; T186-R188 PolarHBondContact O-N 3.08Å; T186-R188 PolarHBondContact OG1-N 2.69Å; T186-R188 PolarHBondContact OG1-O 2.92Å; T186-R188 VanDerWaalsContact OG1-O 3.11Å
187G89.3Confident82.7Confident35 Ų3548.2 Ų48.236%0.36124%0.243SC..SBendtrans66.910.2-170.400000113.7I183I183-G187 WeakPolarHBondContact O-CA 3.24Å; I183-G187 PolarHBondContact O-N 3.49Å
188R85.8Confident81.2Confident160 Ų16050 Ų5060%0.60425%0.251SS*.SBendtrans-133.1134.8-174.8-63.4-177.7-175.7-176.71.2110.9T186T186-R188 PolarHBondContact O-N 3.08Å; T186-R188 PolarHBondContact OG1-N 2.69Å; T186-R188 PolarHBondContact OG1-O 2.92Å; T186-R188 VanDerWaalsContact OG1-O 3.11Å
189A77.4Confident79.6Confident10 Ų1050.4 Ų50.48%0.08326%0.255CS..  trans-49.4133.815900000110.5Q191 T207A189-Q191 PolarHBondContact O-N 2.79Å; A189-Q191 VanDerWaalsContact O-N 3.15Å; A189-T207 PolarHBondContact N-OG1 2.98Å
190P70.4Confident78Confident14 Ų1458.2 Ų58.29%0.09130%0.297CS..  trans-51.3124.8174.7-24.330000110.3Y182 G192Y182-P190 HydrophobicContact CD1-CB 4.31Å; Y182-P190 HydrophobicContact CD1-CG 3.62Å; Y182-P190 HydrophobicContact CE1-CB 4.22Å; Y182-P190 HydrophobicContact CE1-CG 4.01Å; Y182-P190 HydrophobicContact CG-CG 4.26Å; P190-G192 PolarHBondContact O-N 2.81Å
191Q61.4Low76.3Confident171 Ų17160.2 Ų60.280%0.79931%0.308SS*.  trans-79.88.9179.5-65.5-172.1-22.400112.6A189A189-Q191 PolarHBondContact O-N 2.79Å; A189-Q191 VanDerWaalsContact O-N 3.15Å
192G56Low74.4Confident45 Ų4563 Ų6346%0.46433%0.326SS..SBendtrans-72.2164.1177.300000112.6P190 N194P190-G192 PolarHBondContact O-N 2.81Å; G192-N194 PolarHBondContact O-N 2.83Å
193K63.4Low73Confident146 Ų14661.7 Ų61.764%0.63532%0.323SS*.  trans-54112.1174.1-162.6-172.9-171.6-161.80108.7E45 I195E45-K193 WeakPolarHBondContact OE1-CE 3.43Å; E45-K193 IonicContact OE1-NZ 3.93Å; E45-K193 PolarHBondContact OE1-NZ 2.95Å; K193-I195 PolarHBondContact O-N 2.85Å
194N70.9Confident72.2Confident20 Ų2066.2 Ų66.211%0.10735%0.347CS..  trans-73.1121.4178.9-174.2-35.4000108.8G192 Y196 Y197 K198 Y285G192-N194 PolarHBondContact O-N 2.83Å; N194-Y196 PolarHBondContact O-N 3.42Å; N194-Y196 PolarHBondContact OD1-N 3.09Å; N194-Y197 WeakPolarHBondContact CB-O 3.48Å; N194-Y197 WeakPolarHBondContact ND2-CD2 3.48Å; N194-Y197 PolarHBondContact O-N 2.96Å; N194-Y197 WeakPolarHBondContact OD1-CD2 3.46Å; N194-Y197 PolarHBondContact OD1-N 3.31Å; N194-K198 WeakPolarHBondContact O-CG 3.44Å; N194-Y285 PolarHBondContact ND2-OH 2.86Å; N194-Y285 WeakPolarHBondContact OD1-CE2 3.45Å; N194-Y285 PolarHBondContact OD1-OH 3.41Å
195I75.9Confident71.6Confident13 Ų1367.6 Ų67.67%0.06735%0.354CS..SBendtrans-67-20.6-176.167.5-171000113.4E45 K193 D271 F272 Y285E45-I195 WeakPolarHBondContact OE2-CA 3.42Å; K193-I195 PolarHBondContact O-N 2.85Å; I195-D271 HydrophobicContact CD1-CB 4.15Å; I195-D271 HydrophobicContact CG2-CB 4.06Å; I195-F272 HydrophobicContact CD1-CD2 3.76Å; I195-F272 HydrophobicContact CD1-CE2 3.5Å; I195-F272 VanDerWaalsContact CD1-CE2 3.5Å; I195-F272 HydrophobicContact CG1-CE2 4.11Å; I195-Y285 HydrophobicContact CD1-CD2 3.7Å; I195-Y285 HydrophobicContact CD1-CG 4.07Å; I195-Y285 HydrophobicContact CG1-CD2 3.75Å; I195-Y285 HydrophobicContact CG1-CE2 4.14Å; I195-Y285 HydrophobicContact CG1-CG 4.47Å
196Y71.9Confident71.3Confident0 Ų062.9 Ų62.90%034%0.337CS..SBendtrans-104.8-18.1-179.5-67.1-65.7000113.9R42 Y46 L139 D176 N194 F272 Y285R42-Y196 WeakPolarHBondContact CD-O 3.42Å; R42-Y196 WeakPolarHBondContact CG-O 3.25Å; R42-Y196 PolarHBondContact NH1-O 3.06Å; Y46-Y196 HydrophobicContact CD1-CD1 4.39Å; Y46-Y196 HydrophobicContact CD1-CE1 4.26Å; Y46-Y196 AromaticContact CE1-CD1 3.81Å; Y46-Y196 HydrophobicContact CE1-CD1 3.81Å; Y46-Y196 AromaticContact CE1-CE1 3.93Å; Y46-Y196 HydrophobicContact CE1-CE1 3.93Å; L139-Y196 HydrophobicContact CB-CE1 4.41Å; D176-Y196 WeakPolarHBondContact OD2-CE2 3.4Å; D176-Y196 PolarHBondContact OD2-OH 3.04Å; N194-Y196 PolarHBondContact O-N 3.42Å; N194-Y196 PolarHBondContact OD1-N 3.09Å; Y196-F272 HydrophobicContact CE1-CE2 4.15Å; Y196-F272 AromaticContact CE1-CZ 3.86Å; Y196-F272 HydrophobicContact CE1-CZ 3.86Å; Y196-F272 AromaticContact CZ-CE2 3.92Å; Y196-F272 AromaticContact CZ-CZ 3.63Å; Y196-F272 WeakPolarHBondContact OH-CZ 3.34Å; Y196-Y285 AromaticContact CD2-CD1 3.87Å; Y196-Y285 HydrophobicContact CD2-CD1 3.87Å; Y196-Y285 AromaticContact CD2-CD2 4Å; Y196-Y285 HydrophobicContact CD2-CD2 4Å; Y196-Y285 AromaticContact CD2-CE1 3.65Å; Y196-Y285 HydrophobicContact CD2-CE1 3.65Å; Y196-Y285 AromaticContact CD2-CE2 3.82Å; Y196-Y285 HydrophobicContact CD2-CE2 3.82Å; Y196-Y285 HydrophobicContact CD2-CG 4.05Å; Y196-Y285 AromaticContact CD2-CZ 3.65Å; Y196-Y285 AromaticContact CE2-CD1 3.67Å; Y196-Y285 HydrophobicContact CE2-CD1 3.67Å; Y196-Y285 HydrophobicContact CE2-CD2 4.14Å; Y196-Y285 AromaticContact CE2-CE1 3.93Å; Y196-Y285 HydrophobicContact CE2-CE1 3.93Å; Y196-Y285 HydrophobicContact CE2-CE2 4.41Å; Y196-Y285 AromaticContact CE2-CG 3.8Å; Y196-Y285 HydrophobicContact CE2-CG 3.8Å
197Y69.1Low71.3Confident24 Ų2461.6 Ų61.69%0.09433%0.329CS..  trans-139.697.6-170.8-54.3-79.8000110.1W32 Y35 I36 N194W32-Y197 HydrophobicContact CH2-CD1 4.37Å; W32-Y197 AromaticContact CH2-CE1 3.39Å; W32-Y197 HydrophobicContact CH2-CE1 3.39Å; W32-Y197 AromaticContact CH2-CZ 3.6Å; W32-Y197 WeakPolarHBondContact CH2-OH 3.12Å; W32-Y197 AromaticContact CZ2-CE1 3.39Å; W32-Y197 HydrophobicContact CZ2-CE1 3.39Å; W32-Y197 AromaticContact CZ2-CZ 3.69Å; W32-Y197 VanDerWaalsContact CZ2-OH 3.22Å; W32-Y197 WeakPolarHBondContact CZ2-OH 3.39Å; W32-Y197 HydrophobicContact CZ3-CE1 4.19Å; Y35-Y197 AromaticContact CD1-CD1 3.36Å; Y35-Y197 HydrophobicContact CD1-CD1 3.36Å; Y35-Y197 AromaticContact CD1-CE1 3.73Å; Y35-Y197 HydrophobicContact CD1-CE1 3.73Å; Y35-Y197 HydrophobicContact CD1-CG 4.07Å; Y35-Y197 AromaticContact CE1-CD1 3.08Å; Y35-Y197 HydrophobicContact CE1-CD1 3.08Å; Y35-Y197 AromaticContact CE1-CD2 3.97Å; Y35-Y197 HydrophobicContact CE1-CD2 3.97Å; Y35-Y197 AromaticContact CE1-CE1 3.45Å; Y35-Y197 HydrophobicContact CE1-CE1 3.45Å; Y35-Y197 VanDerWaalsContact CE1-CE1 3.45Å; Y35-Y197 HydrophobicContact CE1-CE2 4.27Å; Y35-Y197 AromaticContact CE1-CG 3.38Å; Y35-Y197 HydrophobicContact CE1-CG 3.38Å; Y35-Y197 HydrophobicContact CG-CD1 4.46Å; Y35-Y197 AromaticContact CZ-CD1 3.98Å; Y35-Y197 AromaticContact CZ-CG 3.82Å; I36-Y197 HydrophobicContact CB-CD1 4.47Å; I36-Y197 HydrophobicContact CG1-CD1 3.92Å; I36-Y197 HydrophobicContact CG1-CE1 3.85Å; N194-Y197 WeakPolarHBondContact CB-O 3.48Å; N194-Y197 WeakPolarHBondContact ND2-CD2 3.48Å; N194-Y197 PolarHBondContact O-N 2.96Å; N194-Y197 WeakPolarHBondContact OD1-CD2 3.46Å; N194-Y197 PolarHBondContact OD1-N 3.31Å
198K65.8Low71.5Confident37 Ų3762 Ų6216%0.16133%0.326CS..  trans-118.443.8-175.3-61.8178.8-175.7171.60112.2I36 S41 E45 N194 D200I36-K198 PolarHBondContact O-N 3.18Å; S41-K198 PolarHBondContact O-NZ 3.03Å; E45-K198 WeakPolarHBondContact OE1-CE 3.49Å; E45-K198 IonicContact OE1-NZ 3Å; E45-K198 PolarHBondContact OE1-NZ 3.11Å; E45-K198 WeakPolarHBondContact OE2-CE 3.35Å; E45-K198 IonicContact OE2-NZ 2.8Å; N194-K198 WeakPolarHBondContact O-CG 3.44Å; K198-D200 PolarHBondContact O-N 3.26Å
199S61.9Low72Confident19 Ų1956.5 Ų56.513%0.13331%0.31CS..  trans-72.4126175.2167.60000109.2L34 Y35 L201 Q203L34-S199 WeakPolarHBondContact O-CB 3.18Å; L34-S199 PolarHBondContact O-OG 3.25Å; Y35-S199 VanDerWaalsContact O-CB 3.29Å; Y35-S199 WeakPolarHBondContact O-CB 3.11Å; S199-L201 PolarHBondContact O-N 3.26Å; S199-L201 VanDerWaalsContact OG-CB 3.29Å; S199-L201 WeakPolarHBondContact OG-CB 3.19Å; S199-L201 WeakPolarHBondContact OG-CD1 3.26Å; S199-L201 VanDerWaalsContact OG-CG 3.25Å; S199-L201 WeakPolarHBondContact OG-CG 3.26Å; S199-L201 PolarHBondContact OG-N 2.98Å; S199-Q203 VanDerWaalsContact CB-NE2 3.32Å
200D59.7Low72.8Confident172 Ų17259.6 Ų59.692%0.9233%0.325SS*.  trans-68.1-5174.2-64.1-41.3000112.2K198K198-D200 PolarHBondContact O-N 3.26Å
201L61.9Low74Confident43 Ų4364.6 Ų64.623%0.22534%0.342CS..SBendtrans-67.5139.5176-58.9170.1000109.2L34 S199 Q203 V225 Q226 P228L34-L201 HydrophobicContact CB-CD1 4.01Å; S199-L201 PolarHBondContact O-N 3.26Å; S199-L201 VanDerWaalsContact OG-CB 3.29Å; S199-L201 WeakPolarHBondContact OG-CB 3.19Å; S199-L201 WeakPolarHBondContact OG-CD1 3.26Å; S199-L201 VanDerWaalsContact OG-CG 3.25Å; S199-L201 WeakPolarHBondContact OG-CG 3.26Å; S199-L201 PolarHBondContact OG-N 2.98Å; L201-Q203 WeakPolarHBondContact O-CG 3.35Å; L201-Q203 PolarHBondContact O-N 2.79Å; L201-V225 HydrophobicContact CB-CG1 4.37Å; L201-V225 HydrophobicContact CD1-CG1 3.93Å; L201-Q226 WeakPolarHBondContact CD1-O 3.24Å; L201-P228 HydrophobicContact CD2-CG 3.92Å
202T53.5Low75.5Confident91 Ų9159.4 Ų59.456%0.55832%0.322SS*.  trans-57.8113.5174.8-48.60000108.9Q226T202-Q226 PolarHBondContact OG1-OE1 3.19Å; T202-Q226 VanDerWaalsContact OG1-OE1 3.08Å
203Q64.8Low77.3Confident55 Ų5564.5 Ų64.526%0.25734%0.338SS..EExtended strand (participates in β ladder)trans-112114.9177.1-70.8176.229.800109S199 L201 T224S199-Q203 VanDerWaalsContact CB-NE2 3.32Å; L201-Q203 WeakPolarHBondContact O-CG 3.35Å; L201-Q203 PolarHBondContact O-N 2.79Å; Q203-T224 WeakPolarHBondContact CA-O 3.31Å
204D77.7Confident78.6Confident95 Ų9564.3 Ų64.351%0.50834%0.344SS..EExtended strand (participates in β ladder)trans-94.6128.6159.4-174.850.1000108.5T224D204-T224 PolarHBondContact N-O 2.84Å; D204-T224 PolarHBondContact O-N 3.17Å
205I81.9Confident79.7Confident46 Ų4670.6 Ų70.624%0.23637%0.37CS..EExtended strand (participates in β ladder)trans-119.2103.8176.8-56179.5000107.7L221 D222 Y223I205-L221 HydrophobicContact CG2-CB 4.16Å; I205-L221 HydrophobicContact CG2-CD2 4.12Å; I205-D222 WeakPolarHBondContact CA-O 3.4Å; I205-Y223 HydrophobicContact CD1-CD1 3.97Å; I205-Y223 HydrophobicContact CD1-CE1 3.8Å; I205-Y223 HydrophobicContact CG1-CD1 3.93Å; I205-Y223 HydrophobicContact CG1-CE1 4.2Å; I205-Y223 HydrophobicContact CG2-CE1 4.41Å
206T87.8Confident80.5Confident69 Ų6971.2 Ų71.242%0.42338%0.376SS..EExtended strand (participates in β ladder)trans-82.5127.2170.4-65.70000109L221 D222T206-L221 WeakPolarHBondContact O-CA 3.45Å; T206-D222 PolarHBondContact N-O 3.24Å; T206-D222 VanDerWaalsContact N-O 3.08Å; T206-D222 PolarHBondContact O-N 3.45Å
207T91.6Very high81.5Confident29 Ų2973.6 Ų73.618%0.17839%0.387CS..EExtended strand (participates in β ladder)trans-103.4123.8179.4-570000109.8I183 A189 V209 I219 L221I183-T207 HydrophobicContact CG2-CG2 3.81Å; A189-T207 PolarHBondContact N-OG1 2.98Å; T207-V209 HydrophobicContact CG2-CG2 4.4Å; T207-I219 HydrophobicContact CG2-CG2 4.16Å; T207-L221 HydrophobicContact CG2-CD2 3.89Å
208S93.8Very high82.8Confident42 Ų4273.3 Ų73.329%0.29439%0.386SS..EExtended strand (participates in β ladder)trans-115.2133.6172.4-61.40000109.8I219 T220S208-I219 CarbonylContact O-C 3.56Å; S208-I219 WeakPolarHBondContact O-CA 3.27Å; S208-T220 PolarHBondContact N-O 2.77Å; S208-T220 PolarHBondContact O-N 3.34Å
209V94.9Very high84.2Confident45 Ų4571.6 Ų71.627%0.27338%0.379SS..EExtended strand (participates in β ladder)trans-116.4121.6178.1-170.40000109.3L184 T207 W211 I219L184-V209 HydrophobicContact CD2-CG1 3.73Å; T207-V209 HydrophobicContact CG2-CG2 4.4Å; V209-W211 HydrophobicContact CG1-CZ2 4.46Å; V209-I219 HydrophobicContact CG1-CG1 4.3Å; V209-I219 HydrophobicContact CG2-CG1 4.3Å
210L94.8Very high85.7Confident75 Ų7571.4 Ų71.439%0.39338%0.377SS..EExtended strand (participates in β ladder)trans-95.6122.7174.2178.563.2000110V212 H217 M218L210-V212 HydrophobicContact CG-CG2 4.32Å; L210-H217 PolarHBondContact O-N 3.31Å; L210-M218 HydrophobicContact CB-CB 4.13Å; L210-M218 HydrophobicContact CD2-CB 4.33Å; L210-M218 PolarHBondContact N-O 3.19Å; L210-M218 PolarHBondContact O-N 2.98Å
211W94.5Very high87.1Confident119 Ų11963.2 Ų63.245%0.45133%0.333SS..EExtended strand (participates in β ladder)trans-105.8134.2172.5-63.382000109.7L184 V209 K215 P216L184-W211 HydrophobicContact CD2-CZ2 4.35Å; V209-W211 HydrophobicContact CG1-CZ2 4.46Å; W211-K215 WeakPolarHBondContact CA-O 3.21Å; W211-P216 HydrophobicContact CE3-CB 4.28Å; W211-P216 HydrophobicContact CH2-CB 4.29Å; W211-P216 HydrophobicContact CZ3-CB 4.15Å; W211-P216 HydrophobicContact CZ3-CG 4.27Å
212V93.6Very high88.3Confident63 Ų6363 Ų6338%0.38233%0.332SS..EExtended strand (participates in β ladder)trans-124.9118.7173.2-179.10000106.7L210 N214 K215 H217L210-V212 HydrophobicContact CG-CG2 4.32Å; V212-N214 VanDerWaalsContact C-N 3.29Å; V212-N214 PolarHBondContact O-N 3.45Å; V212-K215 PolarHBondContact N-O 2.95Å; V212-K215 WeakPolarHBondContact O-CB 3.37Å; V212-K215 PolarHBondContact O-N 3.39Å; V212-H217 HydrophobicContact CB-CB 4.24Å; V212-H217 HydrophobicContact CG2-CB 3.75Å
213D93.5Very high89.6Confident151 Ų15159 Ų5981%0.80731%0.307SS*.THydrogen-bonded Turntrans48.747.7-178.2-57.8-31000113.7K215D213-K215 PolarHBondContact O-N 2.82Å
214N91.4Very high90.5Very high143 Ų14357.4 Ų57.477%0.76530%0.301SS*.THydrogen-bonded Turntrans61.219.9-178.3-161.441000114.6V212V212-N214 VanDerWaalsContact C-N 3.29Å; V212-N214 PolarHBondContact O-N 3.45Å
215K92.9Very high90.4Very high151 Ų15152.9 Ų52.966%0.65728%0.277SS*.EExtended strand (participates in β ladder)trans-113.4133.8171.5-63.5179.1-178.5176.70110.2W211 V212 D213 H217W211-K215 WeakPolarHBondContact CA-O 3.21Å; V212-K215 PolarHBondContact N-O 2.95Å; V212-K215 WeakPolarHBondContact O-CB 3.37Å; V212-K215 PolarHBondContact O-N 3.39Å; D213-K215 PolarHBondContact O-N 2.82Å; K215-H217 PolarHBondContact O-N 3.27Å
216P94.1Very high90.1Very high27 Ų2753.9 Ų53.918%0.17528%0.281CS..EExtended strand (participates in β ladder)trans-69.4120.1175.530.7-33.7000108.5L184 W211 P246L184-P216 HydrophobicContact CD1-CB 3.93Å; L184-P216 HydrophobicContact CD1-CG 3.78Å; L184-P216 HydrophobicContact CD2-CB 3.48Å; L184-P216 VanDerWaalsContact CD2-CB 3.48Å; L184-P216 HydrophobicContact CD2-CG 4.27Å; L184-P216 HydrophobicContact CG-CB 4.36Å; W211-P216 HydrophobicContact CE3-CB 4.28Å; W211-P216 HydrophobicContact CH2-CB 4.29Å; W211-P216 HydrophobicContact CZ3-CB 4.15Å; W211-P216 HydrophobicContact CZ3-CG 4.27Å; P216-P246 HydrophobicContact CB-CG 3.86Å; P216-P246 HydrophobicContact CG-CG 4.35Å
217H93.2Very high89.4Confident50 Ų5052 Ų5223%0.23127%0.269CS..EExtended strand (participates in β ladder)trans-106.6-35.7-173-173.573.2000112.1D148 L210 V212 K215D148-H217 PolarHBondContact O-CE1 3Å; L210-H217 PolarHBondContact O-N 3.31Å; V212-H217 HydrophobicContact CB-CB 4.24Å; V212-H217 HydrophobicContact CG2-CB 3.75Å; K215-H217 PolarHBondContact O-N 3.27Å
218M95.5Very high88.2Confident18 Ų1854.7 Ų54.79%0.08929%0.287CS..EExtended strand (participates in β ladder)trans-155.5140.5-175.7-168.5176.3-61.200110.9L210 Y244L210-M218 HydrophobicContact CB-CB 4.13Å; L210-M218 HydrophobicContact CD2-CB 4.33Å; L210-M218 PolarHBondContact N-O 3.19Å; L210-M218 PolarHBondContact O-N 2.98Å; M218-Y244 WeakPolarHBondContact CA-O 3.41Å
219I94.8Very high86.7Confident0 Ų057.4 Ų57.40%030%0.295CS..EExtended strand (participates in β ladder)trans-111.6128165.1-70.7170000107.8Y180 I183 L184 T207 S208 V209 L221 S243 Y244 P246Y180-I219 HydrophobicContact CD1-CD1 3.41Å; Y180-I219 VanDerWaalsContact CD1-CD1 3.41Å; Y180-I219 HydrophobicContact CE1-CD1 3.95Å; Y180-I219 HydrophobicContact CG-CD1 4.36Å; I183-I219 HydrophobicContact CB-CD1 4.12Å; I183-I219 HydrophobicContact CG2-CD1 3.67Å; I183-I219 HydrophobicContact CG2-CG2 4.4Å; L184-I219 HydrophobicContact CD2-CD1 4.03Å; L184-I219 HydrophobicContact CD2-CG1 4.48Å; L184-I219 HydrophobicContact CG-CD1 4.38Å; T207-I219 HydrophobicContact CG2-CG2 4.16Å; S208-I219 CarbonylContact O-C 3.56Å; S208-I219 WeakPolarHBondContact O-CA 3.27Å; V209-I219 HydrophobicContact CG1-CG1 4.3Å; V209-I219 HydrophobicContact CG2-CG1 4.3Å; I219-L221 HydrophobicContact CG2-CD2 3.89Å; I219-L221 HydrophobicContact CG2-CG 4.24Å; I219-S243 CarbonylContact O-C 3.54Å; I219-S243 WeakPolarHBondContact O-CA 3.28Å; I219-Y244 PolarHBondContact N-O 2.78Å; I219-Y244 PolarHBondContact O-N 2.85Å; I219-P246 HydrophobicContact CD1-CB 3.61Å; I219-P246 HydrophobicContact CG1-CB 4.04Å
220T93.1Very high84.9Confident15 Ų1557.7 Ų57.79%0.09231%0.306CS..EExtended strand (participates in β ladder)trans-112.2129.1175.8-61.50000108.9S208 R241 L242 S243S208-T220 PolarHBondContact N-O 2.77Å; S208-T220 PolarHBondContact O-N 3.34Å; T220-R241 VanDerWaalsContact CG2-CD 3.41Å; T220-R241 HydrophobicContact CG2-CG 3.37Å; T220-L242 WeakPolarHBondContact CA-O 3.24Å; T220-S243 PolarHBondContact OG1-OG 2.86Å; T220-S243 VanDerWaalsContact OG1-OG 3.06Å
221L89.3Confident83Confident1 Ų161 Ų611%0.00533%0.332CS..EExtended strand (participates in β ladder)trans-112.2119176.9-57.3-178.5000108.7I205 T206 T207 I219 Y223 R241 L242 Y244I205-L221 HydrophobicContact CG2-CB 4.16Å; I205-L221 HydrophobicContact CG2-CD2 4.12Å; T206-L221 WeakPolarHBondContact O-CA 3.45Å; T207-L221 HydrophobicContact CG2-CD2 3.89Å; I219-L221 HydrophobicContact CG2-CD2 3.89Å; I219-L221 HydrophobicContact CG2-CG 4.24Å; L221-Y223 HydrophobicContact CB-CD2 4.27Å; L221-Y223 HydrophobicContact CB-CE2 3.51Å; L221-Y223 WeakPolarHBondContact CD1-OH 3.48Å; L221-Y223 WeakPolarHBondContact O-CD2 3.35Å; L221-R241 WeakPolarHBondContact O-CA 3.37Å; L221-L242 PolarHBondContact N-O 3.39Å; L221-L242 PolarHBondContact O-N 3.01Å; L221-Y244 HydrophobicContact CB-CE2 4.15Å; L221-Y244 HydrophobicContact CD1-CD2 4.13Å; L221-Y244 HydrophobicContact CD1-CE2 3.67Å; L221-Y244 HydrophobicContact CG-CD2 4.15Å; L221-Y244 HydrophobicContact CG-CE2 3.89Å
222D87.1Confident81Confident37 Ų3764.7 Ų64.720%0.19836%0.355CS..EExtended strand (participates in β ladder)trans-95.4110.1171.9-73-65.9000108.6I205 T206 R241I205-D222 WeakPolarHBondContact CA-O 3.4Å; T206-D222 PolarHBondContact N-O 3.24Å; T206-D222 VanDerWaalsContact N-O 3.08Å; T206-D222 PolarHBondContact O-N 3.45Å; D222-R241 VanDerWaalsContact CG-NH2 3.32Å; D222-R241 IonicContact OD1-CZ 3.23Å; D222-R241 IonicContact OD1-NE 3.32Å; D222-R241 PolarHBondContact OD1-NE 3.06Å; D222-R241 IonicContact OD1-NH2 3.53Å; D222-R241 PolarHBondContact OD1-NH2 3.45Å; D222-R241 VanDerWaalsContact OD1-NH2 3.09Å; D222-R241 IonicContact OD2-CZ 3.39Å; D222-R241 IonicContact OD2-NE 2.72Å; D222-R241 PolarHBondContact OD2-NE 3.12Å; D222-R241 IonicContact OD2-NH2 3.09Å; D222-R241 PolarHBondContact OD2-NH2 3.49Å
223Y82.4Confident79.3Confident8 Ų864.3 Ų64.33%0.03136%0.355CS..EExtended strand (participates in β ladder)trans-93.2123.7179.8-60.8-90.4000109.3Y35 I205 L221 K239 F240 L242 Y244Y35-Y223 HydrophobicContact CD2-CD1 4.3Å; Y35-Y223 HydrophobicContact CE1-CE1 4.47Å; Y35-Y223 AromaticContact CE2-CD1 3.56Å; Y35-Y223 HydrophobicContact CE2-CD1 3.56Å; Y35-Y223 AromaticContact CE2-CE1 3.73Å; Y35-Y223 HydrophobicContact CE2-CE1 3.73Å; Y35-Y223 AromaticContact CZ-CD1 3.91Å; Y35-Y223 AromaticContact CZ-CE1 3.58Å; Y35-Y223 VanDerWaalsContact OH-CE1 3.27Å; Y35-Y223 WeakPolarHBondContact OH-CE1 3.48Å; I205-Y223 HydrophobicContact CD1-CD1 3.97Å; I205-Y223 HydrophobicContact CD1-CE1 3.8Å; I205-Y223 HydrophobicContact CG1-CD1 3.93Å; I205-Y223 HydrophobicContact CG1-CE1 4.2Å; I205-Y223 HydrophobicContact CG2-CE1 4.41Å; L221-Y223 HydrophobicContact CB-CD2 4.27Å; L221-Y223 HydrophobicContact CB-CE2 3.51Å; L221-Y223 WeakPolarHBondContact CD1-OH 3.48Å; L221-Y223 WeakPolarHBondContact O-CD2 3.35Å; Y223-K239 VanDerWaalsContact O-CA 3.28Å; Y223-K239 WeakPolarHBondContact O-CA 3.37Å; Y223-F240 VanDerWaalsContact CB-CZ 3.48Å; Y223-F240 HydrophobicContact CD1-CZ 4.24Å; Y223-F240 AromaticContact CD2-CD2 3.82Å; Y223-F240 HydrophobicContact CD2-CD2 3.82Å; Y223-F240 AromaticContact CD2-CE2 3.35Å; Y223-F240 HydrophobicContact CD2-CE2 3.35Å; Y223-F240 AromaticContact CD2-CZ 3.84Å; Y223-F240 HydrophobicContact CD2-CZ 3.84Å; Y223-F240 AromaticContact CE2-CE2 4Å; Y223-F240 HydrophobicContact CE2-CE2 4Å; Y223-F240 HydrophobicContact CG-CD2 4.31Å; Y223-F240 HydrophobicContact CG-CE1 4.21Å; Y223-F240 AromaticContact CG-CE2 3.65Å; Y223-F240 HydrophobicContact CG-CE2 3.65Å; Y223-F240 AromaticContact CG-CZ 3.59Å; Y223-F240 HydrophobicContact CG-CZ 3.59Å; Y223-F240 PolarHBondContact N-O 3.03Å; Y223-F240 PolarHBondContact O-N 3.44Å; Y223-F240 VanDerWaalsContact O-N 3.08Å; Y223-L242 HydrophobicContact CE2-CB 4.1Å; Y223-L242 HydrophobicContact CE2-CD1 3.99Å; Y223-L242 HydrophobicContact CE2-CG 4.2Å; Y223-Y244 PolarHBondContact OH-OH 3.38Å
224T81.9Confident77.7Confident21 Ų2161.9 Ų61.913%0.12935%0.35CS..EExtended strand (participates in β ladder)trans-109.4112.3168.4-57.60000108.3Q203 D204 L237 K239Q203-T224 WeakPolarHBondContact CA-O 3.31Å; D204-T224 PolarHBondContact N-O 2.84Å; D204-T224 PolarHBondContact O-N 3.17Å; T224-L237 HydrophobicContact CG2-CB 4.25Å; T224-L237 HydrophobicContact CG2-CD1 4.35Å; T224-L237 HydrophobicContact CG2-CD2 3.99Å; T224-L237 HydrophobicContact CG2-CG 4.44Å; T224-K239 HydrophobicContact CG2-CG 4.12Å; T224-K239 WeakPolarHBondContact OG1-CE 3.41Å
225V77.1Confident76.5Confident1 Ų158.9 Ų58.91%0.00634%0.338CS..EExtended strand (participates in β ladder)trans-114.7129.4-178.4-176.20000109.2Y35 L201 V227 S238 F240Y35-V225 HydrophobicContact CD2-CG2 4.24Å; L201-V225 HydrophobicContact CB-CG1 4.37Å; L201-V225 HydrophobicContact CD1-CG1 3.93Å; V225-V227 PolarHBondContact O-N 3.3Å; V225-S238 PolarHBondContact N-O 2.85Å; V225-S238 PolarHBondContact O-N 2.93Å; V225-F240 HydrophobicContact CG2-CE1 3.9Å
226Q75.6Confident75.7Confident67 Ų6757.1 Ų57.131%0.31333%0.332SS..EExtended strand (participates in β ladder)trans-72.3118.1169-78.9176.5-12.700109.9L201 T202 P228 L237L201-Q226 WeakPolarHBondContact CD1-O 3.24Å; T202-Q226 PolarHBondContact OG1-OE1 3.19Å; T202-Q226 VanDerWaalsContact OG1-OE1 3.08Å; Q226-P228 WeakPolarHBondContact O-CD 3.41Å; Q226-L237 HydrophobicContact CB-CD2 4.44Å; Q226-L237 HydrophobicContact CG-CD2 3.43Å; Q226-L237 VanDerWaalsContact CG-CD2 3.43Å
227V72.4Confident74.9Confident30 Ų3060.4 Ų60.418%0.18235%0.348CS..EExtended strand (participates in β ladder)trans-89.8119173.5-1790000107.7L34 V225 E229 E236L34-V227 HydrophobicContact CD1-CB 4.37Å; L34-V227 HydrophobicContact CD1-CG1 3.92Å; L34-V227 HydrophobicContact CD1-CG2 4Å; V225-V227 PolarHBondContact O-N 3.3Å; V227-E229 PolarHBondContact O-N 3.36Å; V227-E236 PolarHBondContact N-O 2.77Å; V227-E236 PolarHBondContact O-N 3.42Å
228P66.7Low74.3Confident84 Ų8459.3 Ų59.355%0.54535%0.346SS..PPolyproline II helixtrans-66116.4171.9-13.127.1000108.5L201 Q226L201-P228 HydrophobicContact CD2-CG 3.92Å; Q226-P228 WeakPolarHBondContact O-CD 3.41Å
229E61.9Low73.6Confident100 Ų10065.1 Ų65.147%0.46737%0.37SS..PPolyproline II helixtrans-93168.8162.9-70.8-159.7145.500110.3V227 S233V227-E229 PolarHBondContact O-N 3.36Å; E229-S233 WeakPolarHBondContact CB-OG 3.27Å; E229-S233 VanDerWaalsContact OE2-CB 3.25Å; E229-S233 WeakPolarHBondContact OE2-CB 3.22Å; E229-S233 PolarHBondContact OE2-OG 2.9Å
230G57.6Low73Confident50 Ų5065.6 Ų65.652%0.51537%0.373SS..PPolyproline II helixtrans-54.5171.2-176.800000113.8Q232 S233G230-Q232 PolarHBondContact O-N 3.46Å; G230-S233 PolarHBondContact O-N 3.23Å
231P53.9Low72.7Confident144 Ų14468 Ų6894%0.93538%0.38SS*.THydrogen-bonded Turntrans-61.83.9-164.521.7-32.1000117.2
232Q53.9Low72.7Confident198 Ų19867.9 Ų67.993%0.92538%0.379SS*.THydrogen-bonded Turntrans-130.67.7-176.6-67.4-167-9.100115.8G230G230-Q232 PolarHBondContact O-N 3.46Å
233S57.1Low73Confident55 Ų5566.6 Ų66.639%0.38537%0.373SS..SBendtrans-119.3150.8175.253.80000113.1E229 G230E229-S233 WeakPolarHBondContact CB-OG 3.27Å; E229-S233 VanDerWaalsContact OE2-CB 3.25Å; E229-S233 WeakPolarHBondContact OE2-CB 3.22Å; E229-S233 PolarHBondContact OE2-OG 2.9Å; G230-S233 PolarHBondContact O-N 3.23Å
234S59.9Low73.6Confident100 Ų10066.6 Ų66.670%0.69937%0.373SS*.PPolyproline II helixtrans-63.9139172.650.20000110.2E236S234-E236 PolarHBondContact O-N 3.15Å
235P66.1Low74.3Confident79 Ų7967 Ų6751%0.51337%0.373SS..PPolyproline II helixtrans-56.5125.7-179.321.2-31000111.2
236E76.3Confident75.3Confident115 Ų11567.2 Ų67.254%0.53737%0.374SS..EExtended strand (participates in β ladder)trans-80.7137.7175.9-167.3-174.1-179.700109.5V227 S234V227-E236 PolarHBondContact N-O 2.77Å; V227-E236 PolarHBondContact O-N 3.42Å; S234-E236 PolarHBondContact O-N 3.15Å
237L77.6Confident76.3Confident96 Ų9664 Ų6450%0.50336%0.359SS..EExtended strand (participates in β ladder)trans-91.2113.7172.8-65.7175.5000109.5T224 Q226T224-L237 HydrophobicContact CG2-CB 4.25Å; T224-L237 HydrophobicContact CG2-CD1 4.35Å; T224-L237 HydrophobicContact CG2-CD2 3.99Å; T224-L237 HydrophobicContact CG2-CG 4.44Å; Q226-L237 HydrophobicContact CB-CD2 4.44Å; Q226-L237 HydrophobicContact CG-CD2 3.43Å; Q226-L237 VanDerWaalsContact CG-CD2 3.43Å
238S79.3Confident77.5Confident27 Ų2767.8 Ų67.819%0.18937%0.37CS..EExtended strand (participates in β ladder)trans-89.7132167.9-163.50000110V225V225-S238 PolarHBondContact N-O 2.85Å; V225-S238 PolarHBondContact O-N 2.93Å
239K81.9Confident78.9Confident139 Ų13964.8 Ų64.860%0.60435%0.349SS*.EExtended strand (participates in β ladder)trans-117.5132.3175.7-64.8-172.8178.9-174.80110.7Y223 T224Y223-K239 VanDerWaalsContact O-CA 3.28Å; Y223-K239 WeakPolarHBondContact O-CA 3.37Å; T224-K239 HydrophobicContact CG2-CG 4.12Å; T224-K239 WeakPolarHBondContact OG1-CE 3.41Å
240F82.4Confident80.6Confident11 Ų1166 Ų665%0.04836%0.358CS..EExtended strand (participates in β ladder)trans-140.8155.8170.267.4-86.1000110.6A28 V31 Y35 Y223 V225 L242A28-F240 HydrophobicContact CB-CD2 4.04Å; A28-F240 HydrophobicContact CB-CG 4.4Å; V31-F240 HydrophobicContact CG2-CD1 3.5Å; V31-F240 VanDerWaalsContact CG2-CD1 3.5Å; V31-F240 HydrophobicContact CG2-CE1 3.49Å; V31-F240 VanDerWaalsContact CG2-CE1 3.49Å; V31-F240 HydrophobicContact CG2-CG 4.38Å; V31-F240 HydrophobicContact CG2-CZ 4.38Å; Y35-F240 HydrophobicContact CD2-CZ 4.28Å; Y35-F240 HydrophobicContact CG-CZ 4.2Å; Y223-F240 VanDerWaalsContact CB-CZ 3.48Å; Y223-F240 HydrophobicContact CD1-CZ 4.24Å; Y223-F240 AromaticContact CD2-CD2 3.82Å; Y223-F240 HydrophobicContact CD2-CD2 3.82Å; Y223-F240 AromaticContact CD2-CE2 3.35Å; Y223-F240 HydrophobicContact CD2-CE2 3.35Å; Y223-F240 AromaticContact CD2-CZ 3.84Å; Y223-F240 HydrophobicContact CD2-CZ 3.84Å; Y223-F240 AromaticContact CE2-CE2 4Å; Y223-F240 HydrophobicContact CE2-CE2 4Å; Y223-F240 HydrophobicContact CG-CD2 4.31Å; Y223-F240 HydrophobicContact CG-CE1 4.21Å; Y223-F240 AromaticContact CG-CE2 3.65Å; Y223-F240 HydrophobicContact CG-CE2 3.65Å; Y223-F240 AromaticContact CG-CZ 3.59Å; Y223-F240 HydrophobicContact CG-CZ 3.59Å; Y223-F240 PolarHBondContact N-O 3.03Å; Y223-F240 PolarHBondContact O-N 3.44Å; Y223-F240 VanDerWaalsContact O-N 3.08Å; V225-F240 HydrophobicContact CG2-CE1 3.9Å; F240-L242 HydrophobicContact CD2-CD1 4.25Å; F240-L242 HydrophobicContact CD2-CG 4.09Å; F240-L242 HydrophobicContact CE2-CD1 3.84Å; F240-L242 HydrophobicContact CE2-CG 4.17Å
241R86.1Confident82.5Confident64 Ų6465.7 Ų65.724%0.24235%0.345CS..EExtended strand (participates in β ladder)trans-122.1132.9-174.4174.7174-77.1-168.7-6.3109.2R8 T220 L221 D222R8-R241 PolarHBondContact O-NH1 3.21Å; T220-R241 VanDerWaalsContact CG2-CD 3.41Å; T220-R241 HydrophobicContact CG2-CG 3.37Å; L221-R241 WeakPolarHBondContact O-CA 3.37Å; D222-R241 VanDerWaalsContact CG-NH2 3.32Å; D222-R241 IonicContact OD1-CZ 3.23Å; D222-R241 IonicContact OD1-NE 3.32Å; D222-R241 PolarHBondContact OD1-NE 3.06Å; D222-R241 IonicContact OD1-NH2 3.53Å; D222-R241 PolarHBondContact OD1-NH2 3.45Å; D222-R241 VanDerWaalsContact OD1-NH2 3.09Å; D222-R241 IonicContact OD2-CZ 3.39Å; D222-R241 IonicContact OD2-NE 2.72Å; D222-R241 PolarHBondContact OD2-NE 3.12Å; D222-R241 IonicContact OD2-NH2 3.09Å; D222-R241 PolarHBondContact OD2-NH2 3.49Å
242L88.7Confident84.6Confident0 Ų058.9 Ų58.90%030%0.301CS..EExtended strand (participates in β ladder)trans-127143.4170.4-61.2172.3000109.7Q22 Y23 W32 T220 L221 Y223 F240 Y244Q22-L242 HydrophobicContact CB-CD2 4.2Å; Y23-L242 HydrophobicContact CE1-CD1 4.49Å; Y23-L242 HydrophobicContact CE1-CD2 4.05Å; W32-L242 HydrophobicContact CZ3-CD1 4.45Å; T220-L242 WeakPolarHBondContact CA-O 3.24Å; L221-L242 PolarHBondContact N-O 3.39Å; L221-L242 PolarHBondContact O-N 3.01Å; Y223-L242 HydrophobicContact CE2-CB 4.1Å; Y223-L242 HydrophobicContact CE2-CD1 3.99Å; Y223-L242 HydrophobicContact CE2-CG 4.2Å; F240-L242 HydrophobicContact CD2-CD1 4.25Å; F240-L242 HydrophobicContact CD2-CG 4.09Å; F240-L242 HydrophobicContact CE2-CD1 3.84Å; F240-L242 HydrophobicContact CE2-CG 4.17Å; L242-Y244 HydrophobicContact CB-CE2 3.64Å; L242-Y244 VanDerWaalsContact CB-OH 3.3Å; L242-Y244 WeakPolarHBondContact CB-OH 3.12Å; L242-Y244 WeakPolarHBondContact CD1-OH 3.05Å
243S93.1Very high86.7Confident9 Ų953.8 Ų53.86%0.06328%0.276CS..EExtended strand (participates in β ladder)trans-118.3139.9-179.4-68.90000110.2T9 Q22 I219 T220T9-S243 PolarHBondContact O-OG 3.19Å; Q22-S243 PolarHBondContact NE2-O 3.24Å; Q22-S243 PolarHBondContact OE1-O 3.38Å; I219-S243 CarbonylContact O-C 3.54Å; I219-S243 WeakPolarHBondContact O-CA 3.28Å; T220-S243 PolarHBondContact OG1-OG 2.86Å; T220-S243 VanDerWaalsContact OG1-OG 3.06Å
244Y95.4Very high88.6Confident9 Ų957.6 Ų57.64%0.03529%0.288CS..EExtended strand (participates in β ladder)trans-134.9145.1-171.4-54.6-87.1000111.2N141 A144 H145 Y180 M218 I219 L221 Y223 L242N141-Y244 WeakPolarHBondContact ND2-CD1 3.31Å; N141-Y244 WeakPolarHBondContact ND2-CE1 3.47Å; A144-Y244 HydrophobicContact CB-CD1 4.07Å; A144-Y244 CarbonylContact O-C 3.56Å; A144-Y244 VanDerWaalsContact O-CA 3.26Å; A144-Y244 WeakPolarHBondContact O-CA 3.37Å; H145-Y244 AromaticContact CD2-CE1 3.92Å; H145-Y244 AromaticContact CE1-CD1 3.97Å; H145-Y244 AromaticContact CE1-CE1 3.27Å; H145-Y244 WeakPolarHBondContact CE1-CE1 3.47Å; H145-Y244 AromaticContact CE1-CZ 3.74Å; H145-Y244 AromaticContact ND1-CE1 3.9Å; H145-Y244 AromaticContact NE2-CE1 3.24Å; H145-Y244 WeakPolarHBondContact NE2-CE1 3.4Å; H145-Y244 AromaticContact NE2-CZ 3.97Å; Y180-Y244 VanDerWaalsContact OH-CB 3.26Å; Y180-Y244 WeakPolarHBondContact OH-CB 3.29Å; M218-Y244 WeakPolarHBondContact CA-O 3.41Å; I219-Y244 PolarHBondContact N-O 2.78Å; I219-Y244 PolarHBondContact O-N 2.85Å; L221-Y244 HydrophobicContact CB-CE2 4.15Å; L221-Y244 HydrophobicContact CD1-CD2 4.13Å; L221-Y244 HydrophobicContact CD1-CE2 3.67Å; L221-Y244 HydrophobicContact CG-CD2 4.15Å; L221-Y244 HydrophobicContact CG-CE2 3.89Å; Y223-Y244 PolarHBondContact OH-OH 3.38Å; L242-Y244 HydrophobicContact CB-CE2 3.64Å; L242-Y244 VanDerWaalsContact CB-OH 3.3Å; L242-Y244 WeakPolarHBondContact CB-OH 3.12Å; L242-Y244 WeakPolarHBondContact CD1-OH 3.05Å
245Y97.3Very high90.5Very high30 Ų3053.5 Ų53.512%0.11826%0.258CS..  trans-77.2128164.9-173-89.6000110.1A144 D148 Q153 H247A144-Y245 PolarHBondContact O-N 2.83Å; D148-Y245 HydrophobicContact CB-CD2 3.68Å; D148-Y245 HydrophobicContact CB-CE2 3.42Å; D148-Y245 VanDerWaalsContact CB-CE2 3.42Å; Q153-Y245 PolarHBondContact NE2-OH 3.16Å; Y245-H247 VanDerWaalsContact C-N 3.32Å; Y245-H247 AromaticContact CD1-CD2 3.81Å; Y245-H247 AromaticContact CD1-CE1 3.3Å; Y245-H247 WeakPolarHBondContact CD1-CE1 3.17Å; Y245-H247 AromaticContact CD1-CG 3.71Å; Y245-H247 AromaticContact CD1-ND1 3.4Å; Y245-H247 WeakPolarHBondContact CD1-ND1 3.46Å; Y245-H247 AromaticContact CD1-NE2 3.56Å; Y245-H247 AromaticContact CE1-CE1 3.8Å; Y245-H247 AromaticContact CE1-ND1 3.63Å; Y245-H247 PolarHBondContact O-N 3.1Å
246P97.2Very high92Very high5 Ų549.8 Ų49.83%0.03223%0.233CC..  trans-81.671.8-173.133.9-36.5000112.4Y180 L184 P216 I219 R248Y180-P246 HydrophobicContact CD1-CB 4.3Å; Y180-P246 HydrophobicContact CG-CB 4.24Å; L184-P246 HydrophobicContact CD1-CB 4.18Å; L184-P246 HydrophobicContact CD2-CB 4.22Å; L184-P246 HydrophobicContact CG-CB 4.39Å; P216-P246 HydrophobicContact CB-CG 3.86Å; P216-P246 HydrophobicContact CG-CG 4.35Å; I219-P246 HydrophobicContact CD1-CB 3.61Å; I219-P246 HydrophobicContact CG1-CB 4.04Å; P246-R248 PolarHBondContact O-N 3.19Å; P246-R248 VanDerWaalsContact O-N 3.09Å
247H97.8Very high93Very high0 Ų046.3 Ų46.30%022%0.22CC..  trans-60.3110.5178.5-69.4-68.9000112F143 H177 Y180 Y245 F252F143-H247 AromaticContact CD1-NE2 3.59Å; F143-H247 AromaticContact CE1-CE1 3.82Å; F143-H247 AromaticContact CE1-NE2 3.68Å; H177-H247 PolarHBondContact CE1-O 2.97Å; H177-H247 PolarHBondContact ND1-O 3.34Å; Y180-H247 HydrophobicContact CD2-CB 4.23Å; Y180-H247 VanDerWaalsContact CD2-N 3.33Å; Y180-H247 WeakPolarHBondContact CD2-O 3.42Å; Y245-H247 VanDerWaalsContact C-N 3.32Å; Y245-H247 AromaticContact CD1-CD2 3.81Å; Y245-H247 AromaticContact CD1-CE1 3.3Å; Y245-H247 WeakPolarHBondContact CD1-CE1 3.17Å; Y245-H247 AromaticContact CD1-CG 3.71Å; Y245-H247 AromaticContact CD1-ND1 3.4Å; Y245-H247 WeakPolarHBondContact CD1-ND1 3.46Å; Y245-H247 AromaticContact CD1-NE2 3.56Å; Y245-H247 AromaticContact CE1-CE1 3.8Å; Y245-H247 AromaticContact CE1-ND1 3.63Å; Y245-H247 PolarHBondContact O-N 3.1Å; H247-F252 HydrophobicContact CB-CB 4.27Å; H247-F252 HydrophobicContact CB-CD2 3.85Å; H247-F252 HydrophobicContact CB-CG 4.35Å; H247-F252 AromaticContact CG-CD2 3.63Å; H247-F252 AromaticContact ND1-CD2 3.61Å
248R97.1Very high94Very high108 Ų10843.7 Ų43.741%0.40822%0.216SC..  trans-73.6143.5168-67.9-174.2172.9-97.16.7110.3D181 L184 P246 D250 N251 F252D181-R248 WeakPolarHBondContact OD1-CB 3.39Å; D181-R248 VanDerWaalsContact OD1-CG 3.3Å; D181-R248 WeakPolarHBondContact OD1-CG 3.07Å; D181-R248 IonicContact OD1-CZ 2.68Å; D181-R248 IonicContact OD1-NH1 3.54Å; D181-R248 PolarHBondContact OD1-NH1 3.45Å; D181-R248 WeakPolarHBondContact OD2-CA 3.17Å; L184-R248 HydrophobicContact CD1-CG 4.26Å; P246-R248 PolarHBondContact O-N 3.19Å; P246-R248 VanDerWaalsContact O-N 3.09Å; R248-D250 VanDerWaalsContact C-N 3.32Å; R248-D250 PolarHBondContact O-N 2.98Å; R248-N251 PolarHBondContact O-N 3.18Å; R248-F252 WeakPolarHBondContact O-CB 3.43Å; R248-F252 PolarHBondContact O-N 3.07Å
249I96.7Very high94.9Very high21 Ų2142.8 Ų42.811%0.10821%0.21CC..Hα-helixtrans-53.2-44.9-174.3-170.9179.8000113.2D181 K253 V268 Y275 F286D181-I249 PolarHBondContact OD2-N 2.85Å; I249-K253 VanDerWaalsContact O-CB 3.24Å; I249-K253 WeakPolarHBondContact O-CB 3.17Å; I249-K253 PolarHBondContact O-N 3.08Å; I249-V268 HydrophobicContact CD1-CG1 4.16Å; I249-Y275 HydrophobicContact CD1-CD1 4.37Å; I249-Y275 HydrophobicContact CD1-CE1 3.68Å; I249-F286 HydrophobicContact CB-CD2 4.14Å; I249-F286 HydrophobicContact CB-CE2 4.06Å; I249-F286 HydrophobicContact CD1-CD1 3.71Å; I249-F286 HydrophobicContact CD1-CD2 4.18Å; I249-F286 HydrophobicContact CD1-CE1 3.63Å; I249-F286 HydrophobicContact CD1-CE2 4.08Å; I249-F286 HydrophobicContact CD1-CG 3.99Å; I249-F286 HydrophobicContact CD1-CZ 3.82Å; I249-F286 HydrophobicContact CG1-CD1 4.46Å; I249-F286 HydrophobicContact CG1-CD2 4.23Å; I249-F286 HydrophobicContact CG1-CE2 4.39Å; I249-F286 HydrophobicContact CG1-CG 4.25Å
250D96.8Very high95.7Very high125 Ų12536.5 Ų36.567%0.66818%0.183SC*.Hα-helixtrans-70.3-43.9-176.2-70.8-29.3000112.1R248 K253 E254R248-D250 VanDerWaalsContact C-N 3.32Å; R248-D250 PolarHBondContact O-N 2.98Å; D250-K253 PolarHBondContact O-N 2.99Å; D250-E254 WeakPolarHBondContact O-CB 3.34Å; D250-E254 PolarHBondContact O-N 3.14Å
251N97.6Very high96.4Very high45 Ų4542.9 Ų42.924%0.24121%0.212CC..Hα-helixtrans-66-42.3176.6171.4-106.6000111.2Q153 R248 K253 E254 I255Q153-N251 PolarHBondContact NE2-OD1 3.21Å; Q153-N251 PolarHBondContact OE1-ND2 3.38Å; Q153-N251 PolarHBondContact OE1-OD1 3.02Å; R248-N251 PolarHBondContact O-N 3.18Å; N251-K253 VanDerWaalsContact C-N 3.32Å; N251-K253 PolarHBondContact O-N 3.29Å; N251-E254 WeakPolarHBondContact O-CB 3.42Å; N251-E254 PolarHBondContact O-N 3.46Å; N251-I255 WeakPolarHBondContact O-CG1 3.42Å; N251-I255 PolarHBondContact O-N 3.21Å
252F98.4Very high96.9Very high0 Ų042.1 Ų42.10%023%0.225CC..Hα-helixtrans-61.8-43.3176.4-164.5-102.8000111.3F143 I175 H177 H247 R248 E254 I255 L256 H288F143-F252 AromaticContact CD1-CE2 3.52Å; F143-F252 HydrophobicContact CD1-CE2 3.52Å; F143-F252 HydrophobicContact CD1-CZ 4.09Å; F143-F252 AromaticContact CE1-CE2 3.83Å; F143-F252 HydrophobicContact CE1-CE2 3.83Å; F143-F252 HydrophobicContact CG-CE2 4.39Å; I175-F252 HydrophobicContact CD1-CZ 3.91Å; I175-F252 HydrophobicContact CG1-CE1 4.41Å; I175-F252 HydrophobicContact CG1-CZ 4.03Å; I175-F252 HydrophobicContact CG2-CE1 4.23Å; H177-F252 AromaticContact CD2-CD1 3.33Å; H177-F252 WeakPolarHBondContact CD2-CD1 3.34Å; H177-F252 AromaticContact CD2-CE1 3.71Å; H177-F252 AromaticContact CD2-CG 3.58Å; H177-F252 AromaticContact NE2-CD1 3.65Å; H177-F252 AromaticContact NE2-CG 3.73Å; H247-F252 HydrophobicContact CB-CB 4.27Å; H247-F252 HydrophobicContact CB-CD2 3.85Å; H247-F252 HydrophobicContact CB-CG 4.35Å; H247-F252 AromaticContact CG-CD2 3.63Å; H247-F252 AromaticContact ND1-CD2 3.61Å; R248-F252 WeakPolarHBondContact O-CB 3.43Å; R248-F252 PolarHBondContact O-N 3.07Å; F252-E254 VanDerWaalsContact C-N 3.32Å; F252-E254 PolarHBondContact O-N 3Å; F252-I255 HydrophobicContact CD2-CD1 4.23Å; F252-I255 WeakPolarHBondContact O-CG1 3.39Å; F252-L256 HydrophobicContact CE1-CD2 4.12Å; F252-L256 WeakPolarHBondContact O-CB 3.4Å; F252-L256 PolarHBondContact O-N 3.1Å; F252-H288 AromaticContact CD1-CD2 3.67Å; F252-H288 AromaticContact CD1-CE1 3.79Å; F252-H288 AromaticContact CD1-NE2 3.52Å; F252-H288 AromaticContact CE1-CD2 3.79Å
253K97.8Very high97.3Very high91 Ų9147.9 Ų47.940%0.39625%0.25SC..Hα-helixtrans-57.7-44.9175.1-177176-174.9177.40111.9I249 D250 N251 T257 H266I249-K253 VanDerWaalsContact O-CB 3.24Å; I249-K253 WeakPolarHBondContact O-CB 3.17Å; I249-K253 PolarHBondContact O-N 3.08Å; D250-K253 PolarHBondContact O-N 2.99Å; N251-K253 VanDerWaalsContact C-N 3.32Å; N251-K253 PolarHBondContact O-N 3.29Å; K253-T257 WeakPolarHBondContact O-CB 3.49Å; K253-T257 PolarHBondContact O-N 3.33Å; K253-T257 PolarHBondContact O-OG1 3.21Å; K253-H266 VanDerWaalsContact CG-CE1 3.48Å; K253-H266 WeakPolarHBondContact CG-CE1 3.46Å
254E98.3Very high97.5Very high136 Ų13648.6 Ų48.664%0.63626%0.255SS*.Hα-helixtrans-61.9-55.2179.2-176-174.1177.800112.2D250 N251 F252 L256 T257 G258D250-E254 WeakPolarHBondContact O-CB 3.34Å; D250-E254 PolarHBondContact O-N 3.14Å; N251-E254 WeakPolarHBondContact O-CB 3.42Å; N251-E254 PolarHBondContact O-N 3.46Å; F252-E254 VanDerWaalsContact C-N 3.32Å; F252-E254 PolarHBondContact O-N 3Å; E254-L256 VanDerWaalsContact C-N 3.26Å; E254-L256 PolarHBondContact O-N 2.85Å; E254-T257 PolarHBondContact O-N 3.09Å; E254-G258 PolarHBondContact O-N 2.86Å
255I98.2Very high97.6Very high14 Ų1453 Ų537%0.07228%0.276CS..Hα-helixtrans-65.1-32.9-178.163.9175.9000111.7K157 L160 N251 F252 G258 A259K157-I255 HydrophobicContact CG-CB 4.42Å; K157-I255 HydrophobicContact CG-CG2 4.26Å; L160-I255 HydrophobicContact CD1-CB 4.22Å; L160-I255 HydrophobicContact CD1-CD1 3.67Å; L160-I255 HydrophobicContact CD1-CG1 3.58Å; N251-I255 WeakPolarHBondContact O-CG1 3.42Å; N251-I255 PolarHBondContact O-N 3.21Å; F252-I255 HydrophobicContact CD2-CD1 4.23Å; F252-I255 WeakPolarHBondContact O-CG1 3.39Å; I255-G258 PolarHBondContact O-N 3.42Å; I255-A259 PolarHBondContact O-N 2.92Å
256L98Very high97.6Very high0 Ų053.2 Ų53.20%028%0.278CS..Hα-helixtrans-69.6-46177.2-169.364.4000111.2L160 L173 I175 F252 E254 G258 A259 F260 H288 V290L160-L256 HydrophobicContact CD1-CD1 4.24Å; L160-L256 HydrophobicContact CD2-CD1 3.77Å; L160-L256 HydrophobicContact CG-CD1 4.46Å; L173-L256 HydrophobicContact CD2-CD1 3.8Å; I175-L256 HydrophobicContact CG2-CD1 4.03Å; I175-L256 HydrophobicContact CG2-CD2 3.59Å; I175-L256 HydrophobicContact CG2-CG 4.49Å; F252-L256 HydrophobicContact CE1-CD2 4.12Å; F252-L256 WeakPolarHBondContact O-CB 3.4Å; F252-L256 PolarHBondContact O-N 3.1Å; E254-L256 VanDerWaalsContact C-N 3.26Å; E254-L256 PolarHBondContact O-N 2.85Å; L256-G258 VanDerWaalsContact C-N 3.27Å; L256-G258 PolarHBondContact O-N 3.42Å; L256-A259 WeakPolarHBondContact O-CB 3.3Å; L256-A259 PolarHBondContact O-N 3.27Å; L256-F260 HydrophobicContact CD1-CE2 4.48Å; L256-F260 WeakPolarHBondContact O-CD2 3.17Å; L256-H288 HydrophobicContact CD2-CB 3.63Å; L256-V290 HydrophobicContact CD2-CG2 3.51Å; L256-V290 HydrophobicContact CG-CG2 3.93Å
257T98.3Very high97.7Very high43 Ų4355.6 Ų55.626%0.26429%0.294SS..Hα-helixtrans-62-36.9172.8-710000111.6K253 E254 A259 F260 H261 G262 H266K253-T257 WeakPolarHBondContact O-CB 3.49Å; K253-T257 PolarHBondContact O-N 3.33Å; K253-T257 PolarHBondContact O-OG1 3.21Å; E254-T257 PolarHBondContact O-N 3.09Å; T257-A259 VanDerWaalsContact C-N 3.33Å; T257-A259 PolarHBondContact O-N 3.06Å; T257-F260 PolarHBondContact O-N 2.98Å; T257-H261 PolarHBondContact O-N 2.81Å; T257-G262 PolarHBondContact O-N 2.88Å; T257-H266 PolarHBondContact OG1-ND1 3.09Å
258G98.3Very high97.6Very high40 Ų4056.9 Ų56.941%0.41230%0.302SS..Hα-helixtrans-60-38.3173.500000113.5E254 I255 L256 F260 H261E254-G258 PolarHBondContact O-N 2.86Å; I255-G258 PolarHBondContact O-N 3.42Å; L256-G258 VanDerWaalsContact C-N 3.27Å; L256-G258 PolarHBondContact O-N 3.42Å; G258-F260 PolarHBondContact O-N 3.36Å; G258-H261 WeakPolarHBondContact O-CA 3.41Å; G258-H261 PolarHBondContact O-N 3.06Å
259A98.4Very high97.6Very high8 Ų854.4 Ų54.47%0.06629%0.293CS..Hα-helixtrans-63.7-24176.700000113.8L160 Q161 A164 I255 L256 T257L160-A259 HydrophobicContact CB-CB 3.74Å; Q161-A259 HydrophobicContact CG-CB 4.27Å; A164-A259 HydrophobicContact CB-CB 4.03Å; I255-A259 PolarHBondContact O-N 2.92Å; L256-A259 WeakPolarHBondContact O-CB 3.3Å; L256-A259 PolarHBondContact O-N 3.27Å; T257-A259 VanDerWaalsContact C-N 3.33Å; T257-A259 PolarHBondContact O-N 3.06Å
260F98.3Very high97.5Very high7 Ų753.6 Ų53.63%0.03129%0.29CS..THydrogen-bonded Turntrans-94.98.9171.6-69.6-94.2000112.9A164 V167 L173 L256 T257 G258 G262 K263 C264 V290 K292A164-F260 HydrophobicContact CB-CD1 4.19Å; A164-F260 HydrophobicContact CB-CD2 3.94Å; A164-F260 HydrophobicContact CB-CE1 3.89Å; A164-F260 HydrophobicContact CB-CE2 3.61Å; A164-F260 HydrophobicContact CB-CG 4.22Å; A164-F260 HydrophobicContact CB-CZ 3.59Å; V167-F260 HydrophobicContact CB-CE1 4.29Å; V167-F260 HydrophobicContact CG2-CE1 4.26Å; V167-F260 HydrophobicContact CG2-CZ 4.19Å; L173-F260 HydrophobicContact CB-CZ 3.94Å; L173-F260 HydrophobicContact CD2-CE2 3.85Å; L173-F260 HydrophobicContact CD2-CZ 3.89Å; L256-F260 HydrophobicContact CD1-CE2 4.48Å; L256-F260 WeakPolarHBondContact O-CD2 3.17Å; T257-F260 PolarHBondContact O-N 2.98Å; G258-F260 PolarHBondContact O-N 3.36Å; F260-G262 PolarHBondContact O-N 3.26Å; F260-K263 WeakPolarHBondContact O-CB 3.33Å; F260-K263 PolarHBondContact O-N 3.29Å; F260-C264 HydrophobicContact CB-CB 3.85Å; F260-C264 HydrophobicContact CD1-CB 4.31Å; F260-C264 HydrophobicContact CG-CB 4.02Å; F260-V290 HydrophobicContact CD1-CG1 4.36Å; F260-V290 HydrophobicContact CD2-CG1 3.6Å; F260-V290 HydrophobicContact CE1-CG1 4.27Å; F260-V290 HydrophobicContact CE2-CB 4Å; F260-V290 HydrophobicContact CE2-CG1 3.51Å; F260-V290 HydrophobicContact CG-CG1 4.04Å; F260-V290 HydrophobicContact CZ-CB 4.23Å; F260-V290 HydrophobicContact CZ-CG1 3.86Å; F260-K292 HydrophobicContact CD1-CB 3.99Å; F260-K292 HydrophobicContact CD1-CD 4.07Å; F260-K292 HydrophobicContact CD1-CG 3.94Å; F260-K292 HydrophobicContact CE1-CB 3.92Å; F260-K292 HydrophobicContact CE1-CD 4.09Å; F260-K292 HydrophobicContact CE1-CG 4.21Å
261H97.2Very high97.3Very high145 Ų14549.2 Ų49.267%0.67127%0.267SS*.THydrogen-bonded Turntrans53.333.5-174.8-48.5123.1000113T257 G258 K263T257-H261 PolarHBondContact O-N 2.81Å; G258-H261 WeakPolarHBondContact O-CA 3.41Å; G258-H261 PolarHBondContact O-N 3.06Å; H261-K263 PolarHBondContact O-N 2.77Å
262G95.5Very high97.1Very high49 Ų4947.8 Ų47.851%0.50526%0.258SS..THydrogen-bonded Turntrans71.21.2-175.500000115.4T257 F260 C264T257-G262 PolarHBondContact O-N 2.88Å; F260-G262 PolarHBondContact O-N 3.26Å; G262-C264 VanDerWaalsContact C-N 3.28Å; G262-C264 PolarHBondContact O-N 3.33Å; G262-C264 VanDerWaalsContact O-N 3.16Å
263K96.9Very high96.8Very high120 Ų12055.1 Ų55.152%0.52229%0.29SS..  trans-90.758.8-179.5-60.8-178.5-178.4179.50111.2F260 H261 T293 A294F260-K263 WeakPolarHBondContact O-CB 3.33Å; F260-K263 PolarHBondContact O-N 3.29Å; H261-K263 PolarHBondContact O-N 2.77Å; K263-T293 PolarHBondContact O-N 3.16Å; K263-T293 PolarHBondContact O-OG1 3.06Å; K263-A294 HydrophobicContact CD-CB 4.24Å
264C98.1Very high96.5Very high24 Ų2456.4 Ų56.416%0.16231%0.306CS..EExtended strand (participates in β ladder)trans-151.1156.5179.862.70000113.9F260 G262 V290 K291F260-C264 HydrophobicContact CB-CB 3.85Å; F260-C264 HydrophobicContact CD1-CB 4.31Å; F260-C264 HydrophobicContact CG-CB 4.02Å; G262-C264 VanDerWaalsContact C-N 3.28Å; G262-C264 PolarHBondContact O-N 3.33Å; G262-C264 VanDerWaalsContact O-N 3.16Å; C264-V290 HydrophobicContact CB-CG1 3.43Å; C264-V290 VanDerWaalsContact CB-CG1 3.43Å; C264-K291 CarbonylContact C-O 3.54Å; C264-K291 WeakPolarHBondContact CA-O 3.29Å; C264-K291 VanDerWaalsContact CB-O 3.27Å; C264-K291 WeakPolarHBondContact CB-O 3.41Å
265E98.1Very high96.2Very high102 Ų10252.5 Ų52.548%0.47729%0.286SS..EExtended strand (participates in β ladder)trans-93.1130160.7-60163.5-148.100107.6V290 K291 T293E265-V290 CarbonylContact O-C 3.57Å; E265-V290 WeakPolarHBondContact O-CA 3.36Å; E265-K291 HydrophobicContact CB-CB 4.28Å; E265-K291 PolarHBondContact N-O 3.49Å; E265-K291 PolarHBondContact O-N 3.23Å; E265-K291 IonicContact OE1-NZ 2.86Å; E265-K291 PolarHBondContact OE1-NZ 3.47Å; E265-K291 IonicContact OE2-NZ 3.2Å; E265-K291 PolarHBondContact OE2-NZ 3.18Å; E265-T293 HydrophobicContact CG-CG2 4.07Å
266H97.9Very high95.8Very high35 Ų3555.9 Ų55.916%0.16231%0.307CS..EExtended strand (participates in β ladder)trans-126.6114.7-174-172166.1000111K253 T257 H288K253-H266 VanDerWaalsContact CG-CE1 3.48Å; K253-H266 WeakPolarHBondContact CG-CE1 3.46Å; T257-H266 PolarHBondContact OG1-ND1 3.09Å; H266-H288 AromaticContact CE1-ND1 3.59Å; H266-H288 AromaticContact NE2-CE1 3.99Å; H266-H288 AromaticContact NE2-CG 3.67Å; H266-H288 AromaticContact NE2-ND1 2.89Å; H266-H288 PolarHBondContact NE2-ND1 2.96Å
267S97.5Very high95.3Very high55 Ų5560.8 Ų60.839%0.38534%0.339SS..EExtended strand (participates in β ladder)trans-114.4145.4174.5-61.50000111.2V289S267-V289 PolarHBondContact N-O 3.27Å; S267-V289 PolarHBondContact O-N 2.72Å
268V97.4Very high94.5Very high27 Ų2762.7 Ų62.716%0.16437%0.367CS..EExtended strand (participates in β ladder)trans-122.9135.8177-171.90000109.7I249 F286 I287I249-V268 HydrophobicContact CD1-CG1 4.16Å; V268-F286 HydrophobicContact CG1-CB 4.25Å; V268-F286 HydrophobicContact CG1-CD1 4.15Å; V268-I287 CarbonylContact C-O 3.4Å; V268-I287 WeakPolarHBondContact CA-O 3.46Å
269Y96.6Very high93.8Very high55 Ų5564 Ų6422%0.21636%0.363CS..EExtended strand (participates in β ladder)trans-122.7152.6180-59.2-92.8000109.6W49 K273 F286 I287 V289W49-Y269 HydrophobicContact CH2-CD2 4.27Å; W49-Y269 HydrophobicContact CZ2-CD1 4.12Å; W49-Y269 AromaticContact CZ2-CD2 3.82Å; W49-Y269 HydrophobicContact CZ2-CD2 3.82Å; W49-Y269 HydrophobicContact CZ2-CE1 4.27Å; W49-Y269 AromaticContact CZ2-CE2 3.99Å; W49-Y269 HydrophobicContact CZ2-CE2 3.99Å; W49-Y269 AromaticContact CZ2-CG 3.89Å; W49-Y269 HydrophobicContact CZ2-CG 3.89Å; Y269-K273 CarbonylContact C-O 3.3Å; Y269-K273 WeakPolarHBondContact CA-O 3.44Å; Y269-K273 VanDerWaalsContact CB-O 3.3Å; Y269-K273 WeakPolarHBondContact CB-O 3.44Å; Y269-F286 CarbonylContact O-C 3.56Å; Y269-F286 WeakPolarHBondContact O-CA 3.35Å; Y269-I287 PolarHBondContact N-O 3.08Å; Y269-I287 PolarHBondContact O-N 3.48Å; Y269-V289 HydrophobicContact CD2-CG2 3.9Å; Y269-V289 HydrophobicContact CE2-CB 4.06Å; Y269-V289 HydrophobicContact CE2-CG2 3.64Å
270G94.3Very high92.8Very high4 Ų470.1 Ų70.14%0.04140%0.404CS..EExtended strand (participates in β ladder)trans-113.4118176.200000108.2F272 K273 Y285G270-F272 VanDerWaalsContact C-N 3.25Å; G270-F272 PolarHBondContact O-N 3.37Å; G270-K273 PolarHBondContact N-O 3.04Å; G270-K273 WeakPolarHBondContact O-CB 3.42Å; G270-K273 PolarHBondContact O-N 3.38Å; G270-Y285 WeakPolarHBondContact CA-O 3.41Å
271D92.6Very high92.2Very high33 Ų3377 Ų7718%0.17644%0.437CS..THydrogen-bonded Turntrans47.647.3-177.8-58-27.1000113.1I195 K273 P283 C284 Y285I195-D271 HydrophobicContact CD1-CB 4.15Å; I195-D271 HydrophobicContact CG2-CB 4.06Å; D271-K273 PolarHBondContact O-N 2.87Å; D271-P283 VanDerWaalsContact OD2-CA 3.22Å; D271-P283 WeakPolarHBondContact OD2-CA 2.99Å; D271-C284 WeakPolarHBondContact OD1-CB 3.36Å; D271-C284 PolarHBondContact OD1-N 2.75Å; D271-C284 PolarHBondContact OD2-N 3.35Å; D271-Y285 PolarHBondContact N-O 2.86Å; D271-Y285 VanDerWaalsContact N-O 3.09Å; D271-Y285 PolarHBondContact OD1-N 2.92Å
272F92.4Very high91.7Very high15 Ų1572.3 Ų72.37%0.06642%0.423CS..THydrogen-bonded Turntrans60.919-177.4-53.8-76.3000115.9Y46 W49 V50 I195 Y196 G270 I287Y46-F272 AromaticContact CD1-CE2 3.84Å; Y46-F272 HydrophobicContact CD1-CE2 3.84Å; Y46-F272 HydrophobicContact CD1-CZ 4.1Å; Y46-F272 HydrophobicContact CD2-CE1 4.47Å; Y46-F272 HydrophobicContact CD2-CE2 4.43Å; Y46-F272 AromaticContact CD2-CZ 3.94Å; Y46-F272 HydrophobicContact CD2-CZ 3.94Å; Y46-F272 HydrophobicContact CG-CD2 4.28Å; Y46-F272 HydrophobicContact CG-CE1 4.3Å; Y46-F272 AromaticContact CG-CE2 3.59Å; Y46-F272 HydrophobicContact CG-CE2 3.59Å; Y46-F272 AromaticContact CG-CZ 3.54Å; Y46-F272 HydrophobicContact CG-CZ 3.54Å; W49-F272 HydrophobicContact CB-CB 4.34Å; W49-F272 HydrophobicContact CD2-CB 4.16Å; W49-F272 AromaticContact CD2-CD1 3.82Å; W49-F272 HydrophobicContact CD2-CD1 3.82Å; W49-F272 HydrophobicContact CD2-CG 4.46Å; W49-F272 AromaticContact CE3-CD1 3.44Å; W49-F272 HydrophobicContact CE3-CD1 3.44Å; W49-F272 VanDerWaalsContact CE3-CD1 3.44Å; W49-F272 AromaticContact CE3-CE1 3.99Å; W49-F272 HydrophobicContact CE3-CE1 3.99Å; W49-F272 HydrophobicContact CE3-CG 4.45Å; W49-F272 HydrophobicContact CG-CB 4.01Å; W49-F272 HydrophobicContact CG-CD1 4.38Å; W49-F272 HydrophobicContact CH2-CD1 4.37Å; W49-F272 AromaticContact CZ3-CD1 3.76Å; W49-F272 HydrophobicContact CZ3-CD1 3.76Å; W49-F272 HydrophobicContact CZ3-CE1 4.09Å; W49-F272 PolarHBondContact NE1-O 3.14Å; V50-F272 HydrophobicContact CG2-CE1 4.06Å; I195-F272 HydrophobicContact CD1-CD2 3.76Å; I195-F272 HydrophobicContact CD1-CE2 3.5Å; I195-F272 VanDerWaalsContact CD1-CE2 3.5Å; I195-F272 HydrophobicContact CG1-CE2 4.11Å; Y196-F272 HydrophobicContact CE1-CE2 4.15Å; Y196-F272 AromaticContact CE1-CZ 3.86Å; Y196-F272 HydrophobicContact CE1-CZ 3.86Å; Y196-F272 AromaticContact CZ-CE2 3.92Å; Y196-F272 AromaticContact CZ-CZ 3.63Å; Y196-F272 WeakPolarHBondContact OH-CZ 3.34Å; G270-F272 VanDerWaalsContact C-N 3.25Å; G270-F272 PolarHBondContact O-N 3.37Å; F272-I287 HydrophobicContact CD1-CD1 4.38Å; F272-I287 HydrophobicContact CD1-CG1 4.05Å; F272-I287 HydrophobicContact CE1-CG1 3.92Å; F272-I287 HydrophobicContact CE1-CG2 4.48Å; F272-I287 HydrophobicContact CG-CD1 4.47Å; F272-I287 HydrophobicContact CZ-CG1 4.35Å
273K92.2Very high91.5Very high155 Ų15570.2 Ų70.267%0.67440%0.4SS*.EExtended strand (participates in β ladder)trans-118.9161.5174.5-62.1172.3-173.5172.10110.6Y269 G270 D271 Y275Y269-K273 CarbonylContact C-O 3.3Å; Y269-K273 WeakPolarHBondContact CA-O 3.44Å; Y269-K273 VanDerWaalsContact CB-O 3.3Å; Y269-K273 WeakPolarHBondContact CB-O 3.44Å; G270-K273 PolarHBondContact N-O 3.04Å; G270-K273 WeakPolarHBondContact O-CB 3.42Å; G270-K273 PolarHBondContact O-N 3.38Å; D271-K273 PolarHBondContact O-N 2.87Å; K273-Y275 PolarHBondContact O-N 2.82Å
274T92.9Very high91.2Very high117 Ų11764.9 Ų64.972%0.71838%0.378SS*.EExtended strand (participates in β ladder)trans-53.7125.9173.1-53.40000109.6
275Y92Very high91Very high55 Ų5564 Ų6422%0.21637%0.371CS..  trans-101.1132.7177.9172-112.1000110.3I249 K273 P277 Q279 P283 F286I249-Y275 HydrophobicContact CD1-CD1 4.37Å; I249-Y275 HydrophobicContact CD1-CE1 3.68Å; K273-Y275 PolarHBondContact O-N 2.82Å; Y275-P277 HydrophobicContact CE1-CG 4.18Å; Y275-Q279 HydrophobicContact CD2-CG 4.43Å; Y275-Q279 HydrophobicContact CE2-CG 4.35Å; Y275-P283 HydrophobicContact CD2-CG 4.28Å; Y275-P283 HydrophobicContact CE2-CG 4.35Å; Y275-F286 HydrophobicContact CD1-CE1 4.26Å; Y275-F286 AromaticContact CD2-CE1 3.92Å; Y275-F286 HydrophobicContact CD2-CE1 3.92Å; Y275-F286 AromaticContact CE1-CE1 3.95Å; Y275-F286 HydrophobicContact CE1-CE1 3.95Å; Y275-F286 AromaticContact CE2-CE1 3.6Å; Y275-F286 HydrophobicContact CE2-CE1 3.6Å; Y275-F286 HydrophobicContact CE2-CZ 4.23Å; Y275-F286 HydrophobicContact CG-CE1 4.24Å; Y275-F286 AromaticContact CZ-CE1 3.6Å
276T89.7Confident91Very high84 Ų8459.2 Ų59.252%0.51535%0.349SS..  trans-122.4128.1169.4-53.10000109.1G278 Q279T276-G278 PolarHBondContact O-N 2.95Å; T276-Q279 VanDerWaalsContact N-OE1 3.16Å; T276-Q279 WeakPolarHBondContact O-CB 3.29Å; T276-Q279 WeakPolarHBondContact O-CG 3.25Å; T276-Q279 PolarHBondContact O-N 2.87Å; T276-Q279 VanDerWaalsContact O-N 3.1Å
277P87.1Confident91Very high103 Ų10357.6 Ų57.667%0.66934%0.342SS*.THydrogen-bonded Turntrans-52.9132.4173.6-26.835.1000111.5Y275Y275-P277 HydrophobicContact CE1-CG 4.18Å
278G80.9Confident91Very high83 Ų8355 Ų5586%0.85632%0.323SS*.THydrogen-bonded Turntrans79.49.4-178.200000115.7T276T276-G278 PolarHBondContact O-N 2.95Å
279Q83.9Confident91.1Very high69 Ų6954.1 Ų54.132%0.32232%0.318SS..  trans-58.9149.3171.467.5-178.131.500112Y275 T276 Q281Y275-Q279 HydrophobicContact CD2-CG 4.43Å; Y275-Q279 HydrophobicContact CE2-CG 4.35Å; T276-Q279 VanDerWaalsContact N-OE1 3.16Å; T276-Q279 WeakPolarHBondContact O-CB 3.29Å; T276-Q279 WeakPolarHBondContact O-CG 3.25Å; T276-Q279 PolarHBondContact O-N 2.87Å; T276-Q279 VanDerWaalsContact O-N 3.1Å; Q279-Q281 VanDerWaalsContact C-N 3.29Å; Q279-Q281 WeakPolarHBondContact CG-O 2.83Å; Q279-Q281 PolarHBondContact NE2-O 3.25Å; Q279-Q281 PolarHBondContact O-N 3.08Å
280S78.4Confident91.2Very high135 Ų13551.5 Ų51.594%0.94431%0.308SS*.SBendtrans-63.1-30.6-172.354.40000114.5
281Q83.9Confident91.4Very high152 Ų15254.2 Ų54.271%0.7132%0.319SS*.SBendtrans-108.4113.8178.4-170.6174.55.400110.3Q279Q279-Q281 VanDerWaalsContact C-N 3.29Å; Q279-Q281 WeakPolarHBondContact CG-O 2.83Å; Q279-Q281 PolarHBondContact NE2-O 3.25Å; Q279-Q281 PolarHBondContact O-N 3.08Å
282A87.3Confident91.7Very high47 Ų4754.3 Ų54.339%0.38832%0.318SS..  trans-65.8128.317300000109.8Y182Y182-A282 HydrophobicContact CD2-CB 3.88Å; Y182-A282 HydrophobicContact CE2-CB 4.39Å
283P91.5Very high91.8Very high4 Ų457.2 Ų57.23%0.02634%0.336CS..  trans-70.8154.417631-34.2000110.5N179 D271 Y275 F286N179-P283 WeakPolarHBondContact CB-O 3.34Å; N179-P283 PolarHBondContact ND2-O 3.46Å; D271-P283 VanDerWaalsContact OD2-CA 3.22Å; D271-P283 WeakPolarHBondContact OD2-CA 2.99Å; Y275-P283 HydrophobicContact CD2-CG 4.28Å; Y275-P283 HydrophobicContact CE2-CG 4.35Å; P283-F286 HydrophobicContact CG-CD1 4.01Å; P283-F286 HydrophobicContact CG-CE1 3.44Å; P283-F286 VanDerWaalsContact CG-CE1 3.44Å; P283-F286 HydrophobicContact CG-CZ 3.87Å
284C90.8Very high91.2Very high9 Ų953.6 Ų53.66%0.06134%0.335CS..SBendtrans-73.3-35.4172-73.20000111.5R178 N179 D271R178-C284 VanDerWaalsContact CG-O 3.29Å; R178-C284 WeakPolarHBondContact CG-O 3.45Å; N179-C284 PolarHBondContact N-O 3.44Å; D271-C284 WeakPolarHBondContact OD1-CB 3.36Å; D271-C284 PolarHBondContact OD1-N 2.75Å; D271-C284 PolarHBondContact OD2-N 3.35Å
285Y94.2Very high91.1Very high4 Ų450.4 Ų50.42%0.01632%0.316CS..EExtended strand (participates in β ladder)trans-133143.8-176.9-65.2-98.6000111.5N141 H177 R178 N194 I195 Y196 G270 D271N141-Y285 HydrophobicContact CB-CD1 4.2Å; N141-Y285 HydrophobicContact CB-CE1 3.7Å; H177-Y285 WeakPolarHBondContact O-CA 3.42Å; R178-Y285 HydrophobicContact CB-CD1 4.48Å; R178-Y285 HydrophobicContact CB-CE1 4.37Å; R178-Y285 HydrophobicContact CG-CE1 4.3Å; N194-Y285 PolarHBondContact ND2-OH 2.86Å; N194-Y285 WeakPolarHBondContact OD1-CE2 3.45Å; N194-Y285 PolarHBondContact OD1-OH 3.41Å; I195-Y285 HydrophobicContact CD1-CD2 3.7Å; I195-Y285 HydrophobicContact CD1-CG 4.07Å; I195-Y285 HydrophobicContact CG1-CD2 3.75Å; I195-Y285 HydrophobicContact CG1-CE2 4.14Å; I195-Y285 HydrophobicContact CG1-CG 4.47Å; Y196-Y285 AromaticContact CD2-CD1 3.87Å; Y196-Y285 HydrophobicContact CD2-CD1 3.87Å; Y196-Y285 AromaticContact CD2-CD2 4Å; Y196-Y285 HydrophobicContact CD2-CD2 4Å; Y196-Y285 AromaticContact CD2-CE1 3.65Å; Y196-Y285 HydrophobicContact CD2-CE1 3.65Å; Y196-Y285 AromaticContact CD2-CE2 3.82Å; Y196-Y285 HydrophobicContact CD2-CE2 3.82Å; Y196-Y285 HydrophobicContact CD2-CG 4.05Å; Y196-Y285 AromaticContact CD2-CZ 3.65Å; Y196-Y285 AromaticContact CE2-CD1 3.67Å; Y196-Y285 HydrophobicContact CE2-CD1 3.67Å; Y196-Y285 HydrophobicContact CE2-CD2 4.14Å; Y196-Y285 AromaticContact CE2-CE1 3.93Å; Y196-Y285 HydrophobicContact CE2-CE1 3.93Å; Y196-Y285 HydrophobicContact CE2-CE2 4.41Å; Y196-Y285 AromaticContact CE2-CG 3.8Å; Y196-Y285 HydrophobicContact CE2-CG 3.8Å; G270-Y285 WeakPolarHBondContact CA-O 3.41Å; D271-Y285 PolarHBondContact N-O 2.86Å; D271-Y285 VanDerWaalsContact N-O 3.09Å; D271-Y285 PolarHBondContact OD1-N 2.92Å
286F96.8Very high91.1Very high3 Ų350.2 Ų50.21%0.01332%0.322CS..EExtended strand (participates in β ladder)trans-99.8125.8164.7-68.1-61.8000109.3D176 H177 N179 I249 V268 Y269 Y275 P283D176-F286 CarbonylContact C-O 3.59Å; D176-F286 WeakPolarHBondContact CA-O 3.3Å; D176-F286 VanDerWaalsContact CB-O 3.3Å; D176-F286 WeakPolarHBondContact CB-O 3.36Å; H177-F286 AromaticContact CE1-CD2 3.71Å; H177-F286 PolarHBondContact N-O 3.23Å; H177-F286 PolarHBondContact O-N 3.1Å; N179-F286 HydrophobicContact CB-CD2 4.24Å; N179-F286 HydrophobicContact CB-CE2 3.85Å; N179-F286 HydrophobicContact CB-CZ 4.49Å; N179-F286 VanDerWaalsContact CG-CE2 3.46Å; N179-F286 WeakPolarHBondContact OD1-CE2 3.48Å; I249-F286 HydrophobicContact CB-CD2 4.14Å; I249-F286 HydrophobicContact CB-CE2 4.06Å; I249-F286 HydrophobicContact CD1-CD1 3.71Å; I249-F286 HydrophobicContact CD1-CD2 4.18Å; I249-F286 HydrophobicContact CD1-CE1 3.63Å; I249-F286 HydrophobicContact CD1-CE2 4.08Å; I249-F286 HydrophobicContact CD1-CG 3.99Å; I249-F286 HydrophobicContact CD1-CZ 3.82Å; I249-F286 HydrophobicContact CG1-CD1 4.46Å; I249-F286 HydrophobicContact CG1-CD2 4.23Å; I249-F286 HydrophobicContact CG1-CE2 4.39Å; I249-F286 HydrophobicContact CG1-CG 4.25Å; V268-F286 HydrophobicContact CG1-CB 4.25Å; V268-F286 HydrophobicContact CG1-CD1 4.15Å; Y269-F286 CarbonylContact O-C 3.56Å; Y269-F286 WeakPolarHBondContact O-CA 3.35Å; Y275-F286 HydrophobicContact CD1-CE1 4.26Å; Y275-F286 AromaticContact CD2-CE1 3.92Å; Y275-F286 HydrophobicContact CD2-CE1 3.92Å; Y275-F286 AromaticContact CE1-CE1 3.95Å; Y275-F286 HydrophobicContact CE1-CE1 3.95Å; Y275-F286 AromaticContact CE2-CE1 3.6Å; Y275-F286 HydrophobicContact CE2-CE1 3.6Å; Y275-F286 HydrophobicContact CE2-CZ 4.23Å; Y275-F286 HydrophobicContact CG-CE1 4.24Å; Y275-F286 AromaticContact CZ-CE1 3.6Å; P283-F286 HydrophobicContact CG-CD1 4.01Å; P283-F286 HydrophobicContact CG-CE1 3.44Å; P283-F286 VanDerWaalsContact CG-CE1 3.44Å; P283-F286 HydrophobicContact CG-CZ 3.87Å
287I98.3Very high91.2Very high0 Ų048.3 Ų48.30%031%0.311CS..EExtended strand (participates in β ladder)trans-109.2116.7177.8-57.179.7000107.5W49 I174 D176 V268 Y269 F272W49-I287 HydrophobicContact CH2-CG2 4.06Å; W49-I287 HydrophobicContact CZ3-CG2 4.36Å; I174-I287 HydrophobicContact CG2-CG2 3.74Å; D176-I287 HydrophobicContact CB-CG1 4.14Å; V268-I287 CarbonylContact C-O 3.4Å; V268-I287 WeakPolarHBondContact CA-O 3.46Å; Y269-I287 PolarHBondContact N-O 3.08Å; Y269-I287 PolarHBondContact O-N 3.48Å; F272-I287 HydrophobicContact CD1-CD1 4.38Å; F272-I287 HydrophobicContact CD1-CG1 4.05Å; F272-I287 HydrophobicContact CE1-CG1 3.92Å; F272-I287 HydrophobicContact CE1-CG2 4.48Å; F272-I287 HydrophobicContact CG-CD1 4.47Å; F272-I287 HydrophobicContact CZ-CG1 4.35Å
288H98.6Very high91.4Very high0 Ų045.1 Ų45.10%029%0.29CS..EExtended strand (participates in β ladder)trans-95.2124.2176.9-63.1-103.4000109.3I174 I175 H177 F252 L256 H266I174-H288 WeakPolarHBondContact CA-O 3.21Å; I175-H288 HydrophobicContact CG2-CB 3.98Å; I175-H288 PolarHBondContact N-O 3.23Å; I175-H288 WeakPolarHBondContact O-CA 3.28Å; I175-H288 WeakPolarHBondContact O-CB 3.34Å; I175-H288 PolarHBondContact O-N 2.82Å; H177-H288 AromaticContact CD2-CD2 3.85Å; H177-H288 AromaticContact CD2-NE2 3.52Å; H177-H288 AromaticContact NE2-NE2 3.19Å; H177-H288 PolarHBondContact NE2-NE2 2.77Å; H177-H288 VanDerWaalsContact NE2-NE2 3.19Å; F252-H288 AromaticContact CD1-CD2 3.67Å; F252-H288 AromaticContact CD1-CE1 3.79Å; F252-H288 AromaticContact CD1-NE2 3.52Å; F252-H288 AromaticContact CE1-CD2 3.79Å; L256-H288 HydrophobicContact CD2-CB 3.63Å; H266-H288 AromaticContact CE1-ND1 3.59Å; H266-H288 AromaticContact NE2-CE1 3.99Å; H266-H288 AromaticContact NE2-CG 3.67Å; H266-H288 AromaticContact NE2-ND1 2.89Å; H266-H288 PolarHBondContact NE2-ND1 2.96Å
289V98.6Very high92.1Very high10 Ų1042.7 Ų42.76%0.06125%0.254CS..EExtended strand (participates in β ladder)trans-110.4115.9170.5-177.50000107.8W49 L53 L173 I174 S267 Y269W49-V289 HydrophobicContact CH2-CG2 3.63Å; W49-V289 HydrophobicContact CZ2-CG2 4.28Å; L53-V289 HydrophobicContact CD2-CG1 4.1Å; L53-V289 HydrophobicContact CD2-CG2 3.86Å; L173-V289 WeakPolarHBondContact O-CA 3.31Å; I174-V289 HydrophobicContact CG2-CG2 4.42Å; S267-V289 PolarHBondContact N-O 3.27Å; S267-V289 PolarHBondContact O-N 2.72Å; Y269-V289 HydrophobicContact CD2-CG2 3.9Å; Y269-V289 HydrophobicContact CE2-CB 4.06Å; Y269-V289 HydrophobicContact CE2-CG2 3.64Å
290V98.6Very high92.6Very high0 Ų040.9 Ų40.90%025%0.25CC..EExtended strand (participates in β ladder)trans-119.2113.2-177.8-172.90000109.5I172 L173 L256 F260 C264 E265I172-V290 CarbonylContact C-O 3.51Å; I172-V290 WeakPolarHBondContact CA-O 3.48Å; L173-V290 HydrophobicContact CB-CB 4.38Å; L173-V290 PolarHBondContact N-O 2.99Å; L173-V290 PolarHBondContact O-N 2.89Å; L256-V290 HydrophobicContact CD2-CG2 3.51Å; L256-V290 HydrophobicContact CG-CG2 3.93Å; F260-V290 HydrophobicContact CD1-CG1 4.36Å; F260-V290 HydrophobicContact CD2-CG1 3.6Å; F260-V290 HydrophobicContact CE1-CG1 4.27Å; F260-V290 HydrophobicContact CE2-CB 4Å; F260-V290 HydrophobicContact CE2-CG1 3.51Å; F260-V290 HydrophobicContact CG-CG1 4.04Å; F260-V290 HydrophobicContact CZ-CB 4.23Å; F260-V290 HydrophobicContact CZ-CG1 3.86Å; C264-V290 HydrophobicContact CB-CG1 3.43Å; C264-V290 VanDerWaalsContact CB-CG1 3.43Å; E265-V290 CarbonylContact O-C 3.57Å; E265-V290 WeakPolarHBondContact O-CA 3.36Å
291K98.6Very high93.6Very high61 Ų6134.2 Ų34.227%0.26520%0.2SC..EExtended strand (participates in β ladder)trans-95.8121.2176.3178.2-179.3159.8-140.60109.5G171 I172 C264 E265 T293G171-K291 WeakPolarHBondContact O-CA 3.46Å; I172-K291 HydrophobicContact CG2-CB 3.95Å; I172-K291 HydrophobicContact CG2-CG 4.1Å; C264-K291 CarbonylContact C-O 3.54Å; C264-K291 WeakPolarHBondContact CA-O 3.29Å; C264-K291 VanDerWaalsContact CB-O 3.27Å; C264-K291 WeakPolarHBondContact CB-O 3.41Å; E265-K291 HydrophobicContact CB-CB 4.28Å; E265-K291 PolarHBondContact N-O 3.49Å; E265-K291 PolarHBondContact O-N 3.23Å; E265-K291 IonicContact OE1-NZ 2.86Å; E265-K291 PolarHBondContact OE1-NZ 3.47Å; E265-K291 IonicContact OE2-NZ 3.2Å; E265-K291 PolarHBondContact OE2-NZ 3.18Å; K291-T293 PolarHBondContact O-N 2.92Å
292K98.4Very high94.4Very high35 Ų3525.2 Ų25.215%0.15216%0.161CC..EExtended strand (participates in β ladder)trans-75.1122.7179.6-172.2167.6-176.8173.20110A164 V167 G170 G171 F260 A294A164-K292 PolarHBondContact O-NZ 2.64Å; V167-K292 HydrophobicContact CB-CD 4.23Å; V167-K292 HydrophobicContact CG1-CB 4.06Å; V167-K292 HydrophobicContact CG1-CD 4.33Å; V167-K292 VanDerWaalsContact O-CD 3.29Å; V167-K292 WeakPolarHBondContact O-CD 3.4Å; V167-K292 PolarHBondContact O-NZ 3.16Å; G170-K292 WeakPolarHBondContact CA-O 3.35Å; G170-K292 PolarHBondContact N-O 2.71Å; G171-K292 PolarHBondContact O-N 3.28Å; F260-K292 HydrophobicContact CD1-CB 3.99Å; F260-K292 HydrophobicContact CD1-CD 4.07Å; F260-K292 HydrophobicContact CD1-CG 3.94Å; F260-K292 HydrophobicContact CE1-CB 3.92Å; F260-K292 HydrophobicContact CE1-CD 4.09Å; F260-K292 HydrophobicContact CE1-CG 4.21Å; K292-A294 WeakPolarHBondContact CE-O 3.25Å; K292-A294 VanDerWaalsContact CG-O 3.28Å; K292-A294 WeakPolarHBondContact CG-O 2.98Å
293T95.1Very high95Very high75 Ų7523.3 Ų23.346%0.4614%0.142SC..  trans-88.4-25.1-176.856.70000112.9K263 E265 K291K263-T293 PolarHBondContact O-N 3.16Å; K263-T293 PolarHBondContact O-OG1 3.06Å; E265-T293 HydrophobicContact CG-CG2 4.07Å; K291-T293 PolarHBondContact O-N 2.92Å
294A80.1Confident95.3Very high79 Ų7925.1 Ų25.165%0.65315%0.153SC*.  trans-150.80-179.900000111.8P169 K263 K292P169-A294 WeakPolarHBondContact CG-OXT 3.26Å; K263-A294 HydrophobicContact CD-CB 4.24Å; K292-A294 WeakPolarHBondContact CE-O 3.25Å; K292-A294 VanDerWaalsContact CG-O 3.28Å; K292-A294 WeakPolarHBondContact CG-O 2.98Å

Retrieved 294 of 294 residues in 90 ms (Link to these results)