A0A060XVP4_ONCMY Loading...

Sulfotransferase

AlphaFold DB , UniProt , Accession A0A060XVP4, Species ONCMY (Oncorhynchus mykiss, Rainbow trout), Gene sult2st3, Length 288 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M61.5Low84.7Confident126 Ų12661.9 Ų61.962%0.62136%0.357SS*.  0147.40-53170.8-162.600108.2V9 Y10 F22M1-V9 WeakPolarHBondContact CA-O 3.41Å; M1-V9 VanDerWaalsContact CB-O 3.3Å; M1-V9 WeakPolarHBondContact CB-O 3.39Å; M1-Y10 HydrophobicContact CE-CD2 3.39Å; M1-Y10 HydrophobicContact CE-CE2 3.3Å; M1-Y10 HydrophobicContact CG-CD2 4.02Å; M1-Y10 HydrophobicContact SD-CD2 3.63Å; M1-Y10 HydrophobicContact SD-CE2 4.17Å; M1-F22 HydrophobicContact CB-CD1 4.27Å; M1-F22 HydrophobicContact CB-CE1 3.6Å; M1-F22 HydrophobicContact CB-CZ 4.48Å; M1-F22 HydrophobicContact CG-CE1 4.36Å; M1-F22 HydrophobicContact SD-CD1 3.53Å; M1-F22 VanDerWaalsContact SD-CD1 3.53Å; M1-F22 HydrophobicContact SD-CE1 3.85Å
2A63.3Low85.6Confident56 Ų5661.9 Ų61.946%0.46338%0.381SS..EExtended strand (participates in β ladder)trans-139.7158.2-17900000110.5V9A2-V9 HydrophobicContact CB-CB 4.48Å; A2-V9 PolarHBondContact N-O 2.71Å; A2-V9 PolarHBondContact O-N 3.17Å
3N70Confident86.5Confident107 Ų10758.9 Ų58.957%0.57236%0.361SS*.EExtended strand (participates in β ladder)trans-93.3131173.2-80.6-23.4000109.5K17N3-K17 VanDerWaalsContact OD1-CE 3.28Å; N3-K17 WeakPolarHBondContact OD1-CE 3.47Å
4D72.7Confident87.3Confident99 Ų9956.8 Ų56.853%0.52935%0.346SS..EExtended strand (participates in β ladder)trans-139.1106.6174.4-173.26.5000110.2N6 Y7 V9D4-N6 PolarHBondContact O-N 3.31Å; D4-N6 VanDerWaalsContact O-N 3.07Å; D4-Y7 PolarHBondContact N-O 3.35Å; D4-Y7 WeakPolarHBondContact O-CA 3.18Å; D4-Y7 PolarHBondContact O-N 3.04Å; D4-V9 HydrophobicContact CB-CG2 4.14Å
5G87.4Confident88Confident53 Ų5353 Ų5355%0.54632%0.323SS..THydrogen-bonded Turntrans50.2-117.1-178.300000112.8Y7 K17G5-Y7 VanDerWaalsContact C-N 3.31Å; G5-Y7 PolarHBondContact O-N 3.43Å; G5-K17 PolarHBondContact O-NZ 3.17Å
6N93.6Very high88.5Confident62 Ų6250.1 Ų50.133%0.33231%0.305SS..THydrogen-bonded Turntrans-80.9-2.6179.2-70-38.5000114.9D4 K17 F140 D142D4-N6 PolarHBondContact O-N 3.31Å; D4-N6 VanDerWaalsContact O-N 3.07Å; N6-K17 WeakPolarHBondContact O-CB 3.21Å; N6-K17 PolarHBondContact O-N 2.8Å; N6-F140 WeakPolarHBondContact CB-O 3.45Å; N6-D142 PolarHBondContact ND2-OD1 2.9Å
7Y96.6Very high89Confident10 Ų1051.8 Ų51.84%0.03931%0.308CS..EExtended strand (participates in β ladder)trans-118.8148.5-170.7-51.3-69.5000114D4 G5 L14 C15 K17 L141 D142 L160D4-Y7 PolarHBondContact N-O 3.35Å; D4-Y7 WeakPolarHBondContact O-CA 3.18Å; D4-Y7 PolarHBondContact O-N 3.04Å; G5-Y7 VanDerWaalsContact C-N 3.31Å; G5-Y7 PolarHBondContact O-N 3.43Å; Y7-L14 HydrophobicContact CD1-CB 4.17Å; Y7-L14 HydrophobicContact CD2-CD1 4.4Å; Y7-L14 HydrophobicContact CD2-CD2 4.29Å; Y7-L14 HydrophobicContact CG-CB 4.07Å; Y7-L14 HydrophobicContact CG-CD2 4.28Å; Y7-C15 CarbonylContact C-O 3.59Å; Y7-C15 VanDerWaalsContact CA-O 3.27Å; Y7-C15 WeakPolarHBondContact CA-O 3.45Å; Y7-K17 WeakPolarHBondContact O-CE 3.35Å; Y7-L141 HydrophobicContact CE1-CD2 3.81Å; Y7-D142 HydrophobicContact CE2-CB 4.3Å; Y7-D142 WeakPolarHBondContact CE2-OD2 3.28Å; Y7-D142 PolarHBondContact OH-N 2.87Å; Y7-L160 HydrophobicContact CD1-CD2 4.01Å; Y7-L160 HydrophobicContact CE1-CD2 3.5Å
8I97Very high89.3Confident7 Ų754.9 Ų54.94%0.03632%0.318CS..EExtended strand (participates in β ladder)trans-93128157.5-54.3-178.5000107.2Y10 C15 K17 H20 F22 F25I8-Y10 PolarHBondContact O-N 2.85Å; I8-C15 PolarHBondContact N-O 2.8Å; I8-C15 PolarHBondContact O-N 2.86Å; I8-K17 HydrophobicContact CD1-CG 4.28Å; I8-K17 HydrophobicContact CG1-CG 3.55Å; I8-H20 WeakPolarHBondContact CD1-O 3.27Å; I8-F22 HydrophobicContact CG2-CD1 4.12Å; I8-F22 HydrophobicContact CG2-CE1 3.43Å; I8-F22 VanDerWaalsContact CG2-CE1 3.43Å; I8-F22 HydrophobicContact CG2-CZ 4.06Å; I8-F25 HydrophobicContact CB-CE2 4.2Å; I8-F25 HydrophobicContact CD1-CE2 4.24Å; I8-F25 HydrophobicContact CG2-CE2 3.87Å
9V96.9Very high89.7Confident36 Ų3654 Ų5422%0.21831%0.314CS..EExtended strand (participates in β ladder)trans-87.1104.5172.5-174.40000108.9M1 A2 D4 L13 L14M1-V9 WeakPolarHBondContact CA-O 3.41Å; M1-V9 VanDerWaalsContact CB-O 3.3Å; M1-V9 WeakPolarHBondContact CB-O 3.39Å; A2-V9 HydrophobicContact CB-CB 4.48Å; A2-V9 PolarHBondContact N-O 2.71Å; A2-V9 PolarHBondContact O-N 3.17Å; D4-V9 HydrophobicContact CB-CG2 4.14Å; V9-L13 WeakPolarHBondContact CA-O 2.87Å; V9-L14 HydrophobicContact CG2-CD2 4.08Å
10Y96.6Very high90.1Very high8 Ų851.6 Ų51.63%0.03130%0.299CS..EExtended strand (participates in β ladder)trans-112.5114.8-180177.9-101.9000109.8M1 I8 G12 L13 F25 E29 M101 L105M1-Y10 HydrophobicContact CE-CD2 3.39Å; M1-Y10 HydrophobicContact CE-CE2 3.3Å; M1-Y10 HydrophobicContact CG-CD2 4.02Å; M1-Y10 HydrophobicContact SD-CD2 3.63Å; M1-Y10 HydrophobicContact SD-CE2 4.17Å; I8-Y10 PolarHBondContact O-N 2.85Å; Y10-G12 PolarHBondContact O-N 2.96Å; Y10-G12 VanDerWaalsContact O-N 3.08Å; Y10-L13 PolarHBondContact N-O 3.48Å; Y10-L13 VanDerWaalsContact O-CB 3.28Å; Y10-L13 WeakPolarHBondContact O-CB 3.3Å; Y10-L13 PolarHBondContact O-N 3.28Å; Y10-F25 HydrophobicContact CD1-CD1 4.08Å; Y10-F25 HydrophobicContact CD1-CE1 4.11Å; Y10-F25 HydrophobicContact CD2-CB 4.04Å; Y10-F25 AromaticContact CD2-CD1 3.98Å; Y10-F25 HydrophobicContact CD2-CD1 3.98Å; Y10-F25 AromaticContact CD2-CD2 3.8Å; Y10-F25 HydrophobicContact CD2-CD2 3.8Å; Y10-F25 HydrophobicContact CD2-CE1 4.42Å; Y10-F25 HydrophobicContact CD2-CE2 4.26Å; Y10-F25 AromaticContact CD2-CG 3.67Å; Y10-F25 HydrophobicContact CD2-CG 3.67Å; Y10-F25 HydrophobicContact CE1-CD1 4.2Å; Y10-F25 HydrophobicContact CE2-CB 3.72Å; Y10-F25 HydrophobicContact CE2-CD1 4.13Å; Y10-F25 HydrophobicContact CE2-CD2 4.37Å; Y10-F25 AromaticContact CE2-CG 3.83Å; Y10-F25 HydrophobicContact CE2-CG 3.83Å; Y10-F25 AromaticContact CG-CD1 3.97Å; Y10-F25 HydrophobicContact CG-CD1 3.97Å; Y10-F25 HydrophobicContact CG-CD2 4.2Å; Y10-F25 HydrophobicContact CG-CE1 4Å; Y10-F25 HydrophobicContact CG-CE2 4.24Å; Y10-F25 HydrophobicContact CG-CG 4.09Å; Y10-F25 HydrophobicContact CG-CZ 4.14Å; Y10-E29 PolarHBondContact OH-OE1 3.47Å; Y10-M101 HydrophobicContact CD1-CE 3.82Å; Y10-M101 HydrophobicContact CD1-SD 4.3Å; Y10-M101 HydrophobicContact CE1-CE 3.82Å; Y10-M101 HydrophobicContact CE1-SD 4.13Å; Y10-L105 HydrophobicContact CD1-CD1 4.39Å; Y10-L105 HydrophobicContact CE1-CD1 4.08Å
11H95.7Very high90.5Very high117 Ų11750.3 Ų50.354%0.54229%0.293SS..THydrogen-bonded Turntrans49.534-173.4-69.4-95.7000114.6L13 L105H11-L13 VanDerWaalsContact C-N 3.3Å; H11-L105 HydrophobicContact CB-CD1 3.78Å; H11-L105 HydrophobicContact CB-CD2 4Å
12G95.5Very high92.1Very high62 Ų6248.4 Ų48.464%0.63928%0.282SS*.THydrogen-bonded Turntrans82.8-0.4-177.600000114.8Y10Y10-G12 PolarHBondContact O-N 2.96Å; Y10-G12 VanDerWaalsContact O-N 3.08Å
13L97.4Very high93.7Very high23 Ų2352.2 Ų52.212%0.1229%0.29CS..EExtended strand (participates in β ladder)trans-92.7140.5176.3-52.4179.9000110.9V9 Y10 H11 M101 P102 L105V9-L13 WeakPolarHBondContact CA-O 2.87Å; Y10-L13 PolarHBondContact N-O 3.48Å; Y10-L13 VanDerWaalsContact O-CB 3.28Å; Y10-L13 WeakPolarHBondContact O-CB 3.3Å; Y10-L13 PolarHBondContact O-N 3.28Å; H11-L13 VanDerWaalsContact C-N 3.3Å; L13-M101 HydrophobicContact CD1-SD 4.49Å; L13-P102 HydrophobicContact CD1-CG 3.97Å; L13-L105 HydrophobicContact CD1-CD1 3.75Å
14L97.6Very high95.1Very high29 Ų2947.2 Ų47.215%0.15226%0.263CS..EExtended strand (participates in β ladder)trans-82.8116.7172.3-59.9177.9000109.7Y7 V9 L160 F161Y7-L14 HydrophobicContact CD1-CB 4.17Å; Y7-L14 HydrophobicContact CD2-CD1 4.4Å; Y7-L14 HydrophobicContact CD2-CD2 4.29Å; Y7-L14 HydrophobicContact CG-CB 4.07Å; Y7-L14 HydrophobicContact CG-CD2 4.28Å; V9-L14 HydrophobicContact CG2-CD2 4.08Å; L14-L160 WeakPolarHBondContact O-CA 3.34Å; L14-F161 PolarHBondContact O-N 2.84Å; L14-F161 VanDerWaalsContact O-N 3.12Å
15C97.8Very high96.3Very high0 Ų042.5 Ų42.50%024%0.238CC..EExtended strand (participates in β ladder)trans-120132.4176.9-61.30000110.1Y7 I8 K17 H20 F25Y7-C15 CarbonylContact C-O 3.59Å; Y7-C15 VanDerWaalsContact CA-O 3.27Å; Y7-C15 WeakPolarHBondContact CA-O 3.45Å; I8-C15 PolarHBondContact N-O 2.8Å; I8-C15 PolarHBondContact O-N 2.86Å; C15-K17 PolarHBondContact O-N 2.78Å; C15-H20 HydrophobicContact CB-CB 4.28Å; C15-F25 HydrophobicContact CB-CE1 4.36Å; C15-F25 HydrophobicContact CB-CZ 3.62Å
16P96.9Very high96.8Very high6 Ų645.3 Ų45.34%0.03924%0.235CC..EExtended strand (participates in β ladder)trans-65.4130.5-176.6-21.632.9000113.6E18 T19 H20 F140 L141 L160P16-E18 PolarHBondContact O-N 3.08Å; P16-T19 PolarHBondContact O-N 3.07Å; P16-H20 VanDerWaalsContact O-CB 3.29Å; P16-H20 WeakPolarHBondContact O-CB 3.46Å; P16-H20 PolarHBondContact O-N 3.24Å; P16-H20 PolarHBondContact O-ND1 3.04Å; P16-H20 VanDerWaalsContact O-ND1 3.1Å; P16-F140 HydrophobicContact CB-CD2 3.84Å; P16-F140 HydrophobicContact CB-CE2 4.2Å; P16-F140 HydrophobicContact CG-CD2 4.38Å; P16-F140 HydrophobicContact CG-CE2 4.34Å; P16-L141 HydrophobicContact CB-CD2 4.33Å; P16-L141 HydrophobicContact CG-CD2 3.89Å; P16-L160 HydrophobicContact CG-CD2 3.71Å
17K95.9Very high97Very high80 Ų8044.3 Ų44.335%0.34823%0.227SC..THydrogen-bonded Turntrans-62.5-26.4175.5-77.1174.3178.2163.90113.9N3 G5 N6 Y7 I8 C15 T19N3-K17 VanDerWaalsContact OD1-CE 3.28Å; N3-K17 WeakPolarHBondContact OD1-CE 3.47Å; G5-K17 PolarHBondContact O-NZ 3.17Å; N6-K17 WeakPolarHBondContact O-CB 3.21Å; N6-K17 PolarHBondContact O-N 2.8Å; Y7-K17 WeakPolarHBondContact O-CE 3.35Å; I8-K17 HydrophobicContact CD1-CG 4.28Å; I8-K17 HydrophobicContact CG1-CG 3.55Å; C15-K17 PolarHBondContact O-N 2.78Å; K17-T19 VanDerWaalsContact C-N 3.27Å; K17-T19 PolarHBondContact O-N 3.01Å
18E95.9Very high97Very high108 Ų10844.3 Ų44.351%0.50523%0.23SC..THydrogen-bonded Turntrans-62.6-35.6179.6-176.261.6-156.600111.9P16 F140P16-E18 PolarHBondContact O-N 3.08Å; E18-F140 HydrophobicContact CB-CB 3.47Å; E18-F140 VanDerWaalsContact CB-CB 3.47Å; E18-F140 HydrophobicContact CB-CD1 4.22Å; E18-F140 HydrophobicContact CB-CD2 4.13Å; E18-F140 HydrophobicContact CB-CG 3.69Å; E18-F140 HydrophobicContact CG-CB 3.95Å; E18-F140 HydrophobicContact CG-CD1 3.95Å; E18-F140 HydrophobicContact CG-CG 3.95Å
19T96.3Very high97.1Very high37 Ų3747.5 Ų47.523%0.22724%0.244CC..THydrogen-bonded Turntrans-113.8-17.3-177.164.10000113.8P16 K17 E81 T82P16-T19 PolarHBondContact O-N 3.07Å; K17-T19 VanDerWaalsContact C-N 3.27Å; K17-T19 PolarHBondContact O-N 3.01Å; T19-E81 VanDerWaalsContact CB-CD 3.5Å; T19-E81 VanDerWaalsContact CB-OE1 3.24Å; T19-E81 WeakPolarHBondContact CB-OE1 3.47Å; T19-E81 WeakPolarHBondContact O-CA 3.5Å; T19-E81 PolarHBondContact OG1-OE1 3.27Å; T19-T82 PolarHBondContact O-N 3.44Å; T19-T82 PolarHBondContact O-OG1 2.94Å; T19-T82 VanDerWaalsContact O-OG1 3.06Å
20H97.9Very high97.1Very high5 Ų552.1 Ų52.12%0.02326%0.263CS..  trans-114.6146.8-177.5-57.370000112.1I8 C15 P16 F25 E80 E81 F161I8-H20 WeakPolarHBondContact CD1-O 3.27Å; C15-H20 HydrophobicContact CB-CB 4.28Å; P16-H20 VanDerWaalsContact O-CB 3.29Å; P16-H20 WeakPolarHBondContact O-CB 3.46Å; P16-H20 PolarHBondContact O-N 3.24Å; P16-H20 PolarHBondContact O-ND1 3.04Å; P16-H20 VanDerWaalsContact O-ND1 3.1Å; H20-F25 HydrophobicContact CB-CE1 4.34Å; H20-F25 HydrophobicContact CB-CE2 4.09Å; H20-F25 HydrophobicContact CB-CZ 3.66Å; H20-F25 AromaticContact CD2-CE1 3.58Å; H20-F25 AromaticContact CD2-CZ 3.68Å; H20-F25 AromaticContact CG-CZ 3.96Å; H20-E80 PolarHBondContact CD2-O 3.4Å; H20-E80 WeakPolarHBondContact NE2-CG 3.35Å; H20-E81 IonicContact CE1-OE1 3.93Å; H20-F161 AromaticContact NE2-CZ 3.7Å
21S97.3Very high97.1Very high25 Ų2552.3 Ų52.318%0.17527%0.265CS..  trans-139.5165.3174.555.10000110E23 S24 F25 T82S21-E23 PolarHBondContact O-N 2.85Å; S21-S24 PolarHBondContact N-OG 3.42Å; S21-S24 PolarHBondContact O-N 3.23Å; S21-S24 PolarHBondContact O-OG 3.19Å; S21-S24 WeakPolarHBondContact OG-CB 3.47Å; S21-S24 PolarHBondContact OG-N 3.32Å; S21-F25 WeakPolarHBondContact O-CD2 3.38Å; S21-F25 PolarHBondContact O-N 3.41Å; S21-F25 VanDerWaalsContact O-N 3.1Å; S21-T82 PolarHBondContact OG-OG1 3.46Å
22F95.9Very high97.2Very high86 Ų8654.9 Ų54.938%0.37727%0.274SS..Hα-helixtrans-62.1-34.2173.2-63-52.5000111.2M1 I8 K26M1-F22 HydrophobicContact CB-CD1 4.27Å; M1-F22 HydrophobicContact CB-CE1 3.6Å; M1-F22 HydrophobicContact CB-CZ 4.48Å; M1-F22 HydrophobicContact CG-CE1 4.36Å; M1-F22 HydrophobicContact SD-CD1 3.53Å; M1-F22 VanDerWaalsContact SD-CD1 3.53Å; M1-F22 HydrophobicContact SD-CE1 3.85Å; I8-F22 HydrophobicContact CG2-CD1 4.12Å; I8-F22 HydrophobicContact CG2-CE1 3.43Å; I8-F22 VanDerWaalsContact CG2-CE1 3.43Å; I8-F22 HydrophobicContact CG2-CZ 4.06Å; F22-K26 WeakPolarHBondContact O-CB 3.44Å; F22-K26 PolarHBondContact O-N 2.85Å
23E97.8Very high97.3Very high137 Ų13752.4 Ų52.464%0.6425%0.247SC*.Hα-helixtrans-65.6-38.7174.6-64.873.3-163.800111.8S21 K26 Y27S21-E23 PolarHBondContact O-N 2.85Å; E23-K26 PolarHBondContact O-N 2.98Å; E23-Y27 WeakPolarHBondContact O-CB 3.45Å; E23-Y27 PolarHBondContact O-N 3.44Å
24S98.1Very high97.3Very high2 Ų254.6 Ų54.61%0.01426%0.256CS..Hα-helixtrans-68.9-40.3176.677.20000112.4S21 Y27 A28 E80 E81S21-S24 PolarHBondContact N-OG 3.42Å; S21-S24 PolarHBondContact O-N 3.23Å; S21-S24 PolarHBondContact O-OG 3.19Å; S21-S24 WeakPolarHBondContact OG-CB 3.47Å; S21-S24 PolarHBondContact OG-N 3.32Å; S24-Y27 PolarHBondContact O-N 3.33Å; S24-A28 WeakPolarHBondContact O-CB 3.38Å; S24-A28 PolarHBondContact O-N 2.95Å; S24-E80 WeakPolarHBondContact CB-O 2.97Å; S24-E80 PolarHBondContact OG-O 3.48Å; S24-E81 VanDerWaalsContact CB-C 3.49Å
25F98.1Very high97.4Very high0 Ų056.2 Ų56.20%027%0.266CS..Hα-helixtrans-62.7-44.4173.1-64.8-53.4000111.7I8 Y10 C15 H20 S21 Y27 A28 E29 E80 M101I8-F25 HydrophobicContact CB-CE2 4.2Å; I8-F25 HydrophobicContact CD1-CE2 4.24Å; I8-F25 HydrophobicContact CG2-CE2 3.87Å; Y10-F25 HydrophobicContact CD1-CD1 4.08Å; Y10-F25 HydrophobicContact CD1-CE1 4.11Å; Y10-F25 HydrophobicContact CD2-CB 4.04Å; Y10-F25 AromaticContact CD2-CD1 3.98Å; Y10-F25 HydrophobicContact CD2-CD1 3.98Å; Y10-F25 AromaticContact CD2-CD2 3.8Å; Y10-F25 HydrophobicContact CD2-CD2 3.8Å; Y10-F25 HydrophobicContact CD2-CE1 4.42Å; Y10-F25 HydrophobicContact CD2-CE2 4.26Å; Y10-F25 AromaticContact CD2-CG 3.67Å; Y10-F25 HydrophobicContact CD2-CG 3.67Å; Y10-F25 HydrophobicContact CE1-CD1 4.2Å; Y10-F25 HydrophobicContact CE2-CB 3.72Å; Y10-F25 HydrophobicContact CE2-CD1 4.13Å; Y10-F25 HydrophobicContact CE2-CD2 4.37Å; Y10-F25 AromaticContact CE2-CG 3.83Å; Y10-F25 HydrophobicContact CE2-CG 3.83Å; Y10-F25 AromaticContact CG-CD1 3.97Å; Y10-F25 HydrophobicContact CG-CD1 3.97Å; Y10-F25 HydrophobicContact CG-CD2 4.2Å; Y10-F25 HydrophobicContact CG-CE1 4Å; Y10-F25 HydrophobicContact CG-CE2 4.24Å; Y10-F25 HydrophobicContact CG-CG 4.09Å; Y10-F25 HydrophobicContact CG-CZ 4.14Å; C15-F25 HydrophobicContact CB-CE1 4.36Å; C15-F25 HydrophobicContact CB-CZ 3.62Å; H20-F25 HydrophobicContact CB-CE1 4.34Å; H20-F25 HydrophobicContact CB-CE2 4.09Å; H20-F25 HydrophobicContact CB-CZ 3.66Å; H20-F25 AromaticContact CD2-CE1 3.58Å; H20-F25 AromaticContact CD2-CZ 3.68Å; H20-F25 AromaticContact CG-CZ 3.96Å; S21-F25 WeakPolarHBondContact O-CD2 3.38Å; S21-F25 PolarHBondContact O-N 3.41Å; S21-F25 VanDerWaalsContact O-N 3.1Å; F25-Y27 VanDerWaalsContact C-N 3.34Å; F25-Y27 PolarHBondContact O-N 3.03Å; F25-A28 WeakPolarHBondContact O-CB 3.37Å; F25-A28 PolarHBondContact O-N 3.27Å; F25-E29 WeakPolarHBondContact O-CG 3.3Å; F25-E29 PolarHBondContact O-N 3.31Å; F25-E80 HydrophobicContact CD1-CB 4.39Å; F25-E80 HydrophobicContact CE1-CB 4.3Å; F25-M101 HydrophobicContact CD1-CE 3.88Å; F25-M101 HydrophobicContact CE1-CE 3.58Å
26K97.8Very high97.4Very high112 Ų11261.8 Ų61.849%0.48729%0.292SS..Hα-helixtrans-60.1-44.4175.6-175.4179.6176.7-175.90111.8F22 E23 A28 E29 E30F22-K26 WeakPolarHBondContact O-CB 3.44Å; F22-K26 PolarHBondContact O-N 2.85Å; E23-K26 PolarHBondContact O-N 2.98Å; K26-A28 VanDerWaalsContact C-N 3.33Å; K26-A28 PolarHBondContact O-N 3.45Å; K26-E29 PolarHBondContact O-N 2.89Å; K26-E30 WeakPolarHBondContact CE-OE1 3.19Å; K26-E30 VanDerWaalsContact CE-OE2 3.27Å; K26-E30 WeakPolarHBondContact CE-OE2 3.5Å; K26-E30 HydrophobicContact CG-CG 4.34Å; K26-E30 IonicContact NZ-OE1 3.91Å; K26-E30 WeakPolarHBondContact O-CB 3.4Å; K26-E30 WeakPolarHBondContact O-CG 3.39Å; K26-E30 PolarHBondContact O-N 3.18Å
27Y97.8Very high97.5Very high40 Ų4061.5 Ų61.516%0.15729%0.29CS..Hα-helixtrans-58.4-46.2174.3174.5-93.9000111.4E23 S24 F25 E29 E30 I31 A84 A85 L88 D89E23-Y27 WeakPolarHBondContact O-CB 3.45Å; E23-Y27 PolarHBondContact O-N 3.44Å; S24-Y27 PolarHBondContact O-N 3.33Å; F25-Y27 VanDerWaalsContact C-N 3.34Å; F25-Y27 PolarHBondContact O-N 3.03Å; Y27-E29 VanDerWaalsContact C-N 3.32Å; Y27-E29 PolarHBondContact O-N 3.29Å; Y27-E30 PolarHBondContact O-N 2.95Å; Y27-I31 HydrophobicContact CE1-CD1 4.17Å; Y27-I31 PolarHBondContact O-N 2.84Å; Y27-A84 HydrophobicContact CD1-CB 4.36Å; Y27-A84 HydrophobicContact CE1-CB 3.95Å; Y27-A85 HydrophobicContact CD1-CB 3.96Å; Y27-A85 HydrophobicContact CD2-CB 3.82Å; Y27-A85 HydrophobicContact CE1-CB 4.29Å; Y27-A85 HydrophobicContact CE2-CB 4.17Å; Y27-A85 HydrophobicContact CG-CB 3.72Å; Y27-L88 HydrophobicContact CE1-CD2 4.34Å; Y27-D89 PolarHBondContact OH-OD1 2.88Å
28A97.8Very high97.6Very high11 Ų1158.1 Ų58.19%0.09128%0.275CS..Hα-helixtrans-61.7-37178.300000112.9S24 F25 K26 I31 L79 P107S24-A28 WeakPolarHBondContact O-CB 3.38Å; S24-A28 PolarHBondContact O-N 2.95Å; F25-A28 WeakPolarHBondContact O-CB 3.37Å; F25-A28 PolarHBondContact O-N 3.27Å; K26-A28 VanDerWaalsContact C-N 3.33Å; K26-A28 PolarHBondContact O-N 3.45Å; A28-I31 VanDerWaalsContact O-CG2 3.31Å; A28-I31 WeakPolarHBondContact O-CG2 3.44Å; A28-L79 HydrophobicContact CB-CD1 4.46Å; A28-L79 HydrophobicContact CB-CD2 4.44Å; A28-L79 HydrophobicContact CB-CG 3.91Å; A28-L79 WeakPolarHBondContact CB-O 3.38Å; A28-P107 VanDerWaalsContact O-CB 3.31Å; A28-P107 WeakPolarHBondContact O-CB 3.43Å
29E97.6Very high97.7Very high74 Ų7453 Ų5335%0.34625%0.251SS..Hα-helixtrans-70.6-40.3175.1-72.3174.3-167.400112.4Y10 F25 K26 Y27 P108Y10-E29 PolarHBondContact OH-OE1 3.47Å; F25-E29 WeakPolarHBondContact O-CG 3.3Å; F25-E29 PolarHBondContact O-N 3.31Å; K26-E29 PolarHBondContact O-N 2.89Å; Y27-E29 VanDerWaalsContact C-N 3.32Å; Y27-E29 PolarHBondContact O-N 3.29Å; E29-P108 VanDerWaalsContact O-CD 3.3Å; E29-P108 WeakPolarHBondContact O-CD 3.46Å
30E97.6Very high97.8Very high132 Ų13251.2 Ų51.262%0.61724%0.241SC*.Hα-helixtrans-90.9-10.1-171.6-69-179.2166.700114.3K26 Y27K26-E30 WeakPolarHBondContact CE-OE1 3.19Å; K26-E30 VanDerWaalsContact CE-OE2 3.27Å; K26-E30 WeakPolarHBondContact CE-OE2 3.5Å; K26-E30 HydrophobicContact CG-CG 4.34Å; K26-E30 IonicContact NZ-OE1 3.91Å; K26-E30 WeakPolarHBondContact O-CB 3.4Å; K26-E30 WeakPolarHBondContact O-CG 3.39Å; K26-E30 PolarHBondContact O-N 3.18Å; Y27-E30 PolarHBondContact O-N 2.95Å
31I97.1Very high97.9Very high12 Ų1251 Ų516%0.06224%0.239CC..  trans-54.7141.5-179.7-166.5170.7000111.8Y27 A28 V33 L79 L88 P107 S109Y27-I31 HydrophobicContact CE1-CD1 4.17Å; Y27-I31 PolarHBondContact O-N 2.84Å; A28-I31 VanDerWaalsContact O-CG2 3.31Å; A28-I31 WeakPolarHBondContact O-CG2 3.44Å; I31-V33 HydrophobicContact CG2-CG2 4.26Å; I31-V33 PolarHBondContact O-N 3.41Å; I31-L79 HydrophobicContact CD1-CD1 3.79Å; I31-L79 HydrophobicContact CG2-CD1 4.13Å; I31-L88 HydrophobicContact CD1-CD2 3.29Å; I31-L88 HydrophobicContact CD1-CG 4.18Å; I31-P107 HydrophobicContact CG2-CB 3.92Å; I31-P107 HydrophobicContact CG2-CG 3.83Å; I31-S109 PolarHBondContact O-OG 2.94Å
32K97.1Very high98Very high171 Ų17149.8 Ų49.874%0.74323%0.231SC*.  trans-86.4109.2168.3-171.4-178.9179.1-171.50109.7R95K32-R95 PolarHBondContact O-NH2 3.38Å
33V98.2Very high98.1Very high11 Ų1145.9 Ų45.97%0.06721%0.214CC..  trans-74.3131171.6177.70000110.2I31 D37 F39 P107 S109 F110 S113 A115I31-V33 HydrophobicContact CG2-CG2 4.26Å; I31-V33 PolarHBondContact O-N 3.41Å; V33-D37 WeakPolarHBondContact CA-OD2 3.42Å; V33-D37 HydrophobicContact CG1-CB 4.28Å; V33-F39 HydrophobicContact CG1-CE2 3.75Å; V33-F39 HydrophobicContact CG1-CZ 3.99Å; V33-F39 HydrophobicContact CG2-CE2 4.42Å; V33-F39 HydrophobicContact CG2-CZ 3.83Å; V33-P107 HydrophobicContact CG2-CG 3.94Å; V33-S109 WeakPolarHBondContact CB-OG 3.42Å; V33-S109 WeakPolarHBondContact CG2-OG 3.45Å; V33-S109 PolarHBondContact N-OG 2.61Å; V33-F110 HydrophobicContact CG2-CB 4.18Å; V33-S113 WeakPolarHBondContact CG1-OG 3.31Å; V33-A115 HydrophobicContact CG1-CB 3.67Å
34E97.9Very high98.1Very high68 Ų6839.6 Ų39.632%0.31819%0.185SC..  trans-90.4155.4174.4-62-177.5175.500110.5E36 D37 S93E34-E36 PolarHBondContact O-N 3.18Å; E34-D37 PolarHBondContact N-OD2 3.22Å; E34-D37 WeakPolarHBondContact O-CB 3.31Å; E34-D37 PolarHBondContact O-N 2.93Å; E34-S93 PolarHBondContact OE2-OG 3.22Å
35D98.3Very high98.1Very high64 Ų6441 Ų4134%0.34219%0.191SC..THydrogen-bonded Turntrans-65.8-27.8179.9-86.4-2.4000111.9S113 K114 A115D35-S113 WeakPolarHBondContact OD1-CA 3.23Å; D35-K114 HydrophobicContact CB-CB 3.94Å; D35-K114 CarbonylContact O-C 3.25Å; D35-K114 VanDerWaalsContact O-C 3.25Å; D35-K114 PolarHBondContact OD1-N 3.05Å; D35-K114 IonicContact OD2-NZ 2.94Å; D35-A115 WeakPolarHBondContact O-CA 3.47Å; D35-A115 PolarHBondContact O-N 2.76Å
36E97.9Very high98.1Very high117 Ų11741 Ų4155%0.54719%0.191SC..THydrogen-bonded Turntrans-87.8-6.2179.5-63.374-163.500113.6E34 P94E34-E36 PolarHBondContact O-N 3.18Å; E36-P94 HydrophobicContact CB-CB 4.16Å; E36-P94 WeakPolarHBondContact O-CB 3.5Å
37D98.6Very high98Very high0 Ų036.2 Ų36.20%017%0.174CC..  trans-61.8144.4-180-77.9-22.8000112.2V33 E34 F39 R95 M97 A115 K116V33-D37 WeakPolarHBondContact CA-OD2 3.42Å; V33-D37 HydrophobicContact CG1-CB 4.28Å; E34-D37 PolarHBondContact N-OD2 3.22Å; E34-D37 WeakPolarHBondContact O-CB 3.31Å; E34-D37 PolarHBondContact O-N 2.93Å; D37-F39 HydrophobicContact CB-CE2 3.9Å; D37-R95 WeakPolarHBondContact OD1-CB 3.33Å; D37-R95 IonicContact OD1-CZ 3.78Å; D37-R95 IonicContact OD1-NE 2.67Å; D37-R95 PolarHBondContact OD1-NE 3.14Å; D37-R95 IonicContact OD1-NH2 3.54Å; D37-R95 PolarHBondContact OD1-NH2 3.5Å; D37-R95 IonicContact OD2-CZ 3.72Å; D37-R95 IonicContact OD2-NE 2.86Å; D37-R95 IonicContact OD2-NH2 2.62Å; D37-R95 PolarHBondContact OD2-NH2 2.67Å; D37-M97 HydrophobicContact CB-CE 4.13Å; D37-A115 HydrophobicContact CB-CB 4Å; D37-A115 CarbonylContact O-C 3.56Å; D37-A115 VanDerWaalsContact O-CA 3.3Å; D37-A115 WeakPolarHBondContact O-CA 3.48Å; D37-A115 WeakPolarHBondContact O-CB 3.42Å; D37-K116 PolarHBondContact O-N 3.22Å
38I98.8Very high98Very high8 Ų834.7 Ų34.74%0.04117%0.168CC..EExtended strand (participates in β ladder)trans-117.3116.1178-48.7-57.6000109.5V55 L59 P94 R95 M97 K116 I118 L203I38-V55 HydrophobicContact CG2-CG1 4.13Å; I38-L59 HydrophobicContact CG1-CD1 4.37Å; I38-L59 HydrophobicContact CG1-CD2 4.35Å; I38-P94 HydrophobicContact CG1-CB 4.34Å; I38-R95 PolarHBondContact N-O 3.21Å; I38-M97 PolarHBondContact O-N 3.15Å; I38-K116 HydrophobicContact CD1-CB 3.87Å; I38-K116 HydrophobicContact CD1-CD 4.33Å; I38-K116 HydrophobicContact CD1-CG 4.46Å; I38-I118 HydrophobicContact CG2-CD1 4Å; I38-L203 HydrophobicContact CD1-CD2 3.59Å; I38-L203 HydrophobicContact CG1-CD2 4.15Å; I38-L203 HydrophobicContact CG2-CD2 3.96Å
39F98.8Very high98Very high0 Ų034.7 Ų34.70%017%0.167CC..EExtended strand (participates in β ladder)trans-97.7125.9173-67.1-92000109.9V33 D37 V41 L79 M97 M106 F110 A115 K116 V117 I118V33-F39 HydrophobicContact CG1-CE2 3.75Å; V33-F39 HydrophobicContact CG1-CZ 3.99Å; V33-F39 HydrophobicContact CG2-CE2 4.42Å; V33-F39 HydrophobicContact CG2-CZ 3.83Å; D37-F39 HydrophobicContact CB-CE2 3.9Å; F39-V41 HydrophobicContact CB-CG2 4.15Å; F39-L79 HydrophobicContact CE1-CD2 4.17Å; F39-M97 WeakPolarHBondContact CA-O 3.14Å; F39-M97 HydrophobicContact CD1-CG 3.66Å; F39-M97 HydrophobicContact CD1-SD 3.98Å; F39-M97 HydrophobicContact CE1-CE 4.33Å; F39-M97 HydrophobicContact CE1-CG 3.65Å; F39-M97 HydrophobicContact CE1-SD 3.3Å; F39-M97 WeakPolarHBondContact CE1-SD 3.44Å; F39-M97 HydrophobicContact CG-CG 4.34Å; F39-M97 HydrophobicContact CZ-CE 4.13Å; F39-M97 HydrophobicContact CZ-CG 4.31Å; F39-M97 HydrophobicContact CZ-SD 3.65Å; F39-M106 HydrophobicContact CD1-CE 3.66Å; F39-M106 HydrophobicContact CE1-CE 3.8Å; F39-M106 HydrophobicContact CG-CE 4.27Å; F39-F110 HydrophobicContact CD2-CD2 4.11Å; F39-F110 HydrophobicContact CD2-CE2 4.05Å; F39-F110 AromaticContact CE2-CD2 3.9Å; F39-F110 HydrophobicContact CE2-CD2 3.9Å; F39-F110 HydrophobicContact CE2-CE2 4.31Å; F39-F110 HydrophobicContact CG-CE2 4.48Å; F39-F110 HydrophobicContact CZ-CD2 4.28Å; F39-A115 HydrophobicContact CD2-CB 3.97Å; F39-A115 HydrophobicContact CE2-CB 3.7Å; F39-K116 PolarHBondContact N-O 3.39Å; F39-V117 HydrophobicContact CB-CG2 4.36Å; F39-V117 CarbonylContact O-C 3.52Å; F39-V117 VanDerWaalsContact O-CA 3.3Å; F39-V117 WeakPolarHBondContact O-CA 3.44Å; F39-I118 PolarHBondContact O-N 3.4Å
40T98.8Very high98Very high1 Ų132.2 Ų32.21%0.00616%0.155CC..EExtended strand (participates in β ladder)trans-101.6115.1160.6-650000109T42 M51 M97 V98 S99 I118T40-T42 HydrophobicContact CG2-CG2 4.23Å; T40-M51 HydrophobicContact CG2-CB 3.44Å; T40-M51 VanDerWaalsContact CG2-CB 3.44Å; T40-M51 HydrophobicContact CG2-CG 3.71Å; T40-M97 PolarHBondContact N-O 2.79Å; T40-V98 HydrophobicContact CG2-CG1 4.09Å; T40-V98 CarbonylContact O-C 3.56Å; T40-V98 WeakPolarHBondContact O-CA 3.36Å; T40-S99 PolarHBondContact O-N 3.48Å; T40-I118 CarbonylContact C-O 3.46Å; T40-I118 WeakPolarHBondContact CA-O 3.3Å
41V98.9Very high98Very high0 Ų026 Ų260%013%0.126CC..EExtended strand (participates in β ladder)trans-113.3133.8-177.7-1740000110.9F39 S99 V117 I118 Y119 V120 W171F39-V41 HydrophobicContact CB-CG2 4.15Å; V41-S99 WeakPolarHBondContact CA-O 3.37Å; V41-S99 WeakPolarHBondContact CG1-O 3.47Å; V41-V117 HydrophobicContact CG2-CG1 4.18Å; V41-I118 PolarHBondContact N-O 2.82Å; V41-Y119 HydrophobicContact CB-CD2 4Å; V41-Y119 HydrophobicContact CB-CE2 4.49Å; V41-Y119 HydrophobicContact CG1-CD2 4.1Å; V41-Y119 HydrophobicContact CG1-CE2 4.1Å; V41-Y119 WeakPolarHBondContact O-CA 3.2Å; V41-Y119 WeakPolarHBondContact O-CD2 3.41Å; V41-V120 PolarHBondContact O-N 3.17Å; V41-W171 HydrophobicContact CB-CH2 4.29Å; V41-W171 HydrophobicContact CB-CZ2 4Å; V41-W171 HydrophobicContact CG1-CD2 4.15Å; V41-W171 VanDerWaalsContact CG1-CE2 3.42Å; V41-W171 HydrophobicContact CG1-CH2 4.3Å; V41-W171 HydrophobicContact CG1-CZ2 3.53Å; V41-W171 HydrophobicContact CG2-CH2 3.7Å; V41-W171 HydrophobicContact CG2-CZ2 3.73Å; V41-W171 HydrophobicContact CG2-CZ3 4.3Å
42T98.8Very high98.1Very high0 Ų025.4 Ų25.40%012%0.123CC..EExtended strand (participates in β ladder)trans-145.4147.1-176.161.40000109.6T40 T48 S99 H100 V120T40-T42 HydrophobicContact CG2-CG2 4.23Å; T42-T48 HydrophobicContact CG2-CG2 4.46Å; T42-T48 PolarHBondContact OG1-OG1 3.08Å; T42-S99 PolarHBondContact N-O 2.71Å; T42-S99 VanDerWaalsContact N-O 3.13Å; T42-H100 WeakPolarHBondContact O-CA 3.43Å; T42-H100 PolarHBondContact O-ND1 3.13Å; T42-H100 PolarHBondContact OG1-CE1 2.65Å; T42-H100 PolarHBondContact OG1-ND1 2.87Å; T42-V120 HydrophobicContact CG2-CB 3.74Å; T42-V120 HydrophobicContact CG2-CG2 4.22Å
43Y98.8Very high98.1Very high3 Ų317.2 Ų17.21%0.0129%0.087CC..  trans-68143.2157.3-175.3-90.2000108.6K45 S46 V127 F154 V159 L160 G162 W164 H167Y43-K45 PolarHBondContact O-N 3.29Å; Y43-S46 WeakPolarHBondContact O-CB 3.08Å; Y43-S46 PolarHBondContact O-N 2.86Å; Y43-S46 VanDerWaalsContact O-N 3.15Å; Y43-S46 PolarHBondContact O-OG 2.96Å; Y43-V127 HydrophobicContact CD1-CG1 3.63Å; Y43-V127 HydrophobicContact CE1-CG1 3.65Å; Y43-F154 AromaticContact CE1-CE2 3.96Å; Y43-F154 HydrophobicContact CE1-CE2 3.96Å; Y43-F154 HydrophobicContact CE1-CZ 4.17Å; Y43-V159 WeakPolarHBondContact OH-CG2 3.43Å; Y43-L160 PolarHBondContact OH-O 3.32Å; Y43-G162 PolarHBondContact OH-O 3.05Å; Y43-W164 AromaticContact CD1-CD1 3.67Å; Y43-W164 HydrophobicContact CD1-CG 4.5Å; Y43-W164 HydrophobicContact CD2-CB 4.38Å; Y43-W164 HydrophobicContact CE1-CB 4.34Å; Y43-W164 HydrophobicContact CE2-CB 4.19Å; Y43-W164 AromaticContact CG-CD1 3.74Å; Y43-W164 HydrophobicContact CG-CG 4.46Å; Y43-H167 HydrophobicContact CD2-CB 3.76Å; Y43-H167 AromaticContact CD2-CG 3.82Å; Y43-H167 HydrophobicContact CE2-CB 4.46Å
44P98.4Very high98.1Very high6 Ų616.7 Ų16.74%0.0398%0.084CC..THydrogen-bonded Turntrans-45.8138.4-179.7-29.332.7000113.2S46 H100 V127 L160 F161P44-S46 VanDerWaalsContact C-N 3.31Å; P44-S46 PolarHBondContact O-N 2.89Å; P44-H100 HydrophobicContact CG-CB 4.22Å; P44-V127 WeakPolarHBondContact O-CG1 3.47Å; P44-L160 HydrophobicContact CG-CB 4.49Å; P44-F161 HydrophobicContact CG-CB 4.03Å; P44-F161 HydrophobicContact CG-CD2 3.4Å; P44-F161 VanDerWaalsContact CG-CD2 3.4Å; P44-F161 HydrophobicContact CG-CE2 4.18Å; P44-F161 HydrophobicContact CG-CG 4.01Å
45K97.9Very high98.1Very high30 Ų3013.6 Ų13.613%0.137%0.07CC..THydrogen-bonded Turntrans70.616179.7-36.3-51.7-61.5-177.60115.9Y43 R122 V127 F134Y43-K45 PolarHBondContact O-N 3.29Å; K45-R122 PolarHBondContact O-NH1 3.38Å; K45-V127 HydrophobicContact CB-CG1 4.48Å; K45-F134 HydrophobicContact CD-CB 4.36Å; K45-F134 HydrophobicContact CD-CD1 4Å; K45-F134 HydrophobicContact CD-CG 4.25Å; K45-F134 VanDerWaalsContact NZ-CG 3.31Å
46S98.3Very high98.1Very high0 Ų011.3 Ų11.30%06%0.058CC..SBendtrans-92.29.2176.2-50.80000115.1Y43 P44Y43-S46 WeakPolarHBondContact O-CB 3.08Å; Y43-S46 PolarHBondContact O-N 2.86Å; Y43-S46 VanDerWaalsContact O-N 3.15Å; Y43-S46 PolarHBondContact O-OG 2.96Å; P44-S46 VanDerWaalsContact C-N 3.31Å; P44-S46 PolarHBondContact O-N 2.89Å
47G95.4Very high98.1Very high13 Ų135.7 Ų5.713%0.1343%0.032CC..SBendtrans108.219.9177.500000115.5T49 W50 M51G47-T49 VanDerWaalsContact C-N 3.32Å; G47-T49 PolarHBondContact O-N 3.22Å; G47-W50 VanDerWaalsContact O-CB 3.26Å; G47-W50 WeakPolarHBondContact O-CB 3.37Å; G47-W50 PolarHBondContact O-N 3.34Å; G47-M51 PolarHBondContact O-N 3.45Å
48T98.1Very high98.1Very high7 Ų75.8 Ų5.84%0.0433%0.032CC..Hα-helixtrans-49.9-48179.1-32.70000112.9T42 W50 M51 Q52 W78 V98 H100T42-T48 HydrophobicContact CG2-CG2 4.46Å; T42-T48 PolarHBondContact OG1-OG1 3.08Å; T48-W50 PolarHBondContact O-N 3.23Å; T48-M51 CarbonylContact O-C 3.59Å; T48-M51 WeakPolarHBondContact O-CB 3.04Å; T48-M51 PolarHBondContact O-N 2.95Å; T48-Q52 WeakPolarHBondContact O-CG 3.44Å; T48-Q52 PolarHBondContact O-N 3.33Å; T48-W78 HydrophobicContact CG2-CZ2 3.84Å; T48-V98 HydrophobicContact CG2-CB 3.83Å; T48-V98 HydrophobicContact CG2-CG1 3.73Å; T48-V98 HydrophobicContact CG2-CG2 4.14Å; T48-H100 PolarHBondContact OG1-CE1 3.16Å; T48-H100 VanDerWaalsContact OG1-CE1 3.3Å
49T97.1Very high98Very high11 Ų116.7 Ų6.77%0.0674%0.038CC..Hα-helixtrans-62.1-32.7179.2-56.40000113G47 M51 Q52 E53 M224 S230 Y232 F247G47-T49 VanDerWaalsContact C-N 3.32Å; G47-T49 PolarHBondContact O-N 3.22Å; T49-M51 VanDerWaalsContact C-N 3.34Å; T49-Q52 PolarHBondContact O-N 3.44Å; T49-E53 PolarHBondContact O-N 2.98Å; T49-E53 VanDerWaalsContact O-N 3.1Å; T49-M224 HydrophobicContact CG2-CE 4.15Å; T49-S230 VanDerWaalsContact CG2-O 3.26Å; T49-S230 WeakPolarHBondContact CG2-O 3.34Å; T49-Y232 HydrophobicContact CG2-CE2 3.94Å; T49-F247 HydrophobicContact CG2-CE1 4.23Å; T49-F247 VanDerWaalsContact OG1-CE1 3.32Å; T49-F247 WeakPolarHBondContact OG1-CE1 3.4Å
50W97.8Very high97.9Very high23 Ų239.5 Ų9.59%0.0875%0.053CC..Hα-helixtrans-65-43.3175-157.3-3.5000110.7G47 T48 E53 I54 Y185 M188 I189 L192 C219 M224G47-W50 VanDerWaalsContact O-CB 3.26Å; G47-W50 WeakPolarHBondContact O-CB 3.37Å; G47-W50 PolarHBondContact O-N 3.34Å; T48-W50 PolarHBondContact O-N 3.23Å; W50-E53 WeakPolarHBondContact O-CB 3.31Å; W50-E53 PolarHBondContact O-N 2.71Å; W50-E53 VanDerWaalsContact O-N 3.15Å; W50-I54 VanDerWaalsContact CD1-CD1 3.45Å; W50-I54 HydrophobicContact CG-CD1 3.98Å; W50-I54 VanDerWaalsContact O-CG1 3.29Å; W50-I54 WeakPolarHBondContact O-CG1 3.48Å; W50-I54 PolarHBondContact O-N 3.03Å; W50-Y185 HydrophobicContact CE3-CD2 4.08Å; W50-Y185 AromaticContact CE3-CE2 3.67Å; W50-Y185 HydrophobicContact CE3-CE2 3.67Å; W50-Y185 HydrophobicContact CZ3-CD2 4.23Å; W50-Y185 AromaticContact CZ3-CE2 3.82Å; W50-Y185 HydrophobicContact CZ3-CE2 3.82Å; W50-M188 HydrophobicContact CD2-CE 4.28Å; W50-M188 HydrophobicContact CD2-SD 4.29Å; W50-M188 HydrophobicContact CE3-CB 4.04Å; W50-M188 HydrophobicContact CE3-CE 3.61Å; W50-M188 HydrophobicContact CE3-SD 4.1Å; W50-M188 HydrophobicContact CH2-CB 3.67Å; W50-M188 HydrophobicContact CZ2-CB 4.31Å; W50-M188 HydrophobicContact CZ3-CB 3.52Å; W50-M188 HydrophobicContact CZ3-CE 4.11Å; W50-I189 HydrophobicContact CH2-CD1 3.65Å; W50-I189 HydrophobicContact CH2-CG1 4.14Å; W50-I189 HydrophobicContact CZ3-CD1 3.67Å; W50-I189 HydrophobicContact CZ3-CG1 3.95Å; W50-L192 HydrophobicContact CZ2-CD1 3.91Å; W50-L192 HydrophobicContact CZ2-CD2 4Å; W50-L192 HydrophobicContact CZ2-CG 4.41Å; W50-C219 PolarHBondContact NE1-O 2.83Å; W50-M224 HydrophobicContact CG-SD 4.24Å
51M98.3Very high97.8Very high0 Ų011.1 Ų11.10%07%0.069CC..Hα-helixtrans-69.3-34.7175.1-64.4-55.1-53.500113.4T40 G47 T48 T49 E53 I54 V55 I118 V120 M188 L199T40-M51 HydrophobicContact CG2-CB 3.44Å; T40-M51 VanDerWaalsContact CG2-CB 3.44Å; T40-M51 HydrophobicContact CG2-CG 3.71Å; G47-M51 PolarHBondContact O-N 3.45Å; T48-M51 CarbonylContact O-C 3.59Å; T48-M51 WeakPolarHBondContact O-CB 3.04Å; T48-M51 PolarHBondContact O-N 2.95Å; T49-M51 VanDerWaalsContact C-N 3.34Å; M51-E53 PolarHBondContact O-N 2.91Å; M51-I54 HydrophobicContact CE-CG2 4.44Å; M51-I54 PolarHBondContact O-N 2.74Å; M51-I54 HydrophobicContact SD-CD1 4.2Å; M51-V55 HydrophobicContact CE-CG2 3.61Å; M51-V55 WeakPolarHBondContact O-CB 3.3Å; M51-V55 WeakPolarHBondContact O-CG2 3.37Å; M51-V55 PolarHBondContact O-N 2.84Å; M51-I118 HydrophobicContact CE-CD1 4.25Å; M51-I118 HydrophobicContact CE-CG2 3.77Å; M51-V120 HydrophobicContact CG-CG2 3.67Å; M51-V120 HydrophobicContact SD-CG2 4Å; M51-M188 HydrophobicContact SD-SD 3.77Å; M51-L199 HydrophobicContact CE-CD1 3.9Å; M51-L199 HydrophobicContact CE-CD2 4.14Å
52Q97.9Very high97.7Very high0 Ų011.1 Ų11.10%07%0.069CC..Hα-helixtrans-60.6-30.5171.3-68.6178-58.500111.3T48 T49 P56 N72 R75 V76 W78 V98T48-Q52 WeakPolarHBondContact O-CG 3.44Å; T48-Q52 PolarHBondContact O-N 3.33Å; T49-Q52 PolarHBondContact O-N 3.44Å; Q52-P56 VanDerWaalsContact O-CD 3.24Å; Q52-P56 WeakPolarHBondContact O-CD 3.4Å; Q52-P56 VanDerWaalsContact O-CG 3.22Å; Q52-P56 WeakPolarHBondContact O-CG 3.07Å; Q52-N72 HydrophobicContact CB-CB 4.16Å; Q52-N72 PolarHBondContact OE1-ND2 2.91Å; Q52-R75 PolarHBondContact O-NH1 2.85Å; Q52-V76 HydrophobicContact CB-CB 4.18Å; Q52-V76 HydrophobicContact CB-CG2 4.45Å; Q52-V76 HydrophobicContact CG-CB 3.95Å; Q52-V76 HydrophobicContact CG-CG1 4.05Å; Q52-V76 PolarHBondContact NE2-O 3.3Å; Q52-W78 VanDerWaalsContact CD-CH2 3.42Å; Q52-V98 HydrophobicContact CG-CG1 3.76Å; Q52-V98 HydrophobicContact CG-CG2 4.32Å
53E97.8Very high97.6Very high0 Ų014.6 Ų14.60%09%0.088CC..Hα-helixtrans-75.3-47.3171.1-159.275.9162.100111.9T49 W50 M51 L57 V67 R75 H218 M224 N227 S230T49-E53 PolarHBondContact O-N 2.98Å; T49-E53 VanDerWaalsContact O-N 3.1Å; W50-E53 WeakPolarHBondContact O-CB 3.31Å; W50-E53 PolarHBondContact O-N 2.71Å; W50-E53 VanDerWaalsContact O-N 3.15Å; M51-E53 PolarHBondContact O-N 2.91Å; E53-L57 WeakPolarHBondContact O-CG 3.22Å; E53-V67 HydrophobicContact CG-CG1 4.37Å; E53-R75 IonicContact OE2-CZ 3.72Å; E53-R75 IonicContact OE2-NH1 3.93Å; E53-R75 IonicContact OE2-NH2 2.82Å; E53-R75 PolarHBondContact OE2-NH2 2.98Å; E53-H218 IonicContact OE1-CD2 2.6Å; E53-H218 IonicContact OE1-CE1 3.66Å; E53-H218 IonicContact OE1-NE2 3.92Å; E53-H218 PolarHBondContact OE1-NE2 3.08Å; E53-M224 HydrophobicContact CB-CE 3.54Å; E53-M224 HydrophobicContact CB-SD 3.92Å; E53-M224 HydrophobicContact CG-CE 3.94Å; E53-M224 HydrophobicContact CG-CG 4.21Å; E53-M224 HydrophobicContact CG-SD 4.05Å; E53-N227 PolarHBondContact OE1-ND2 3.06Å; E53-S230 VanDerWaalsContact CD-OG 3.3Å; E53-S230 PolarHBondContact OE1-OG 3.43Å; E53-S230 PolarHBondContact OE2-OG 3.13Å
54I98.2Very high97.5Very high0 Ų016.3 Ų16.30%010%0.097CC..Hα-helixtrans-70-53.6-171.9-70.8163.2000113.1W50 M51 L57 V58 M188 L192 L196 L199 C219W50-I54 VanDerWaalsContact CD1-CD1 3.45Å; W50-I54 HydrophobicContact CG-CD1 3.98Å; W50-I54 VanDerWaalsContact O-CG1 3.29Å; W50-I54 WeakPolarHBondContact O-CG1 3.48Å; W50-I54 PolarHBondContact O-N 3.03Å; M51-I54 HydrophobicContact CE-CG2 4.44Å; M51-I54 PolarHBondContact O-N 2.74Å; M51-I54 HydrophobicContact SD-CD1 4.2Å; I54-L57 WeakPolarHBondContact O-CB 3.3Å; I54-L57 PolarHBondContact O-N 3.5Å; I54-L57 VanDerWaalsContact O-N 3.1Å; I54-V58 HydrophobicContact CG2-CG2 3.98Å; I54-V58 WeakPolarHBondContact O-CG2 3.05Å; I54-V58 PolarHBondContact O-N 2.91Å; I54-M188 HydrophobicContact CD1-SD 4.41Å; I54-L192 HydrophobicContact CD1-CD1 3.84Å; I54-L196 HydrophobicContact CB-CD2 4.45Å; I54-L196 HydrophobicContact CG1-CD2 4.34Å; I54-L196 HydrophobicContact CG2-CD2 3.43Å; I54-L196 VanDerWaalsContact CG2-CD2 3.43Å; I54-L199 HydrophobicContact CG2-CD1 3.71Å; I54-C219 HydrophobicContact CG1-CB 4.04Å
55V98.3Very high97.4Very high2 Ų219.6 Ų19.61%0.01212%0.117CC..Hα-helixtrans-55-51.5-169.6172.90000112.8I38 M51 L57 V58 L59 A96 I118I38-V55 HydrophobicContact CG2-CG1 4.13Å; M51-V55 HydrophobicContact CE-CG2 3.61Å; M51-V55 WeakPolarHBondContact O-CB 3.3Å; M51-V55 WeakPolarHBondContact O-CG2 3.37Å; M51-V55 PolarHBondContact O-N 2.84Å; V55-L57 VanDerWaalsContact C-N 3.29Å; V55-L57 PolarHBondContact O-N 3.35Å; V55-V58 PolarHBondContact O-N 3.26Å; V55-L59 HydrophobicContact CG1-CD1 3.78Å; V55-L59 HydrophobicContact CG1-CG 4.21Å; V55-L59 WeakPolarHBondContact O-CG 3.36Å; V55-L59 PolarHBondContact O-N 3.17Å; V55-A96 HydrophobicContact CG1-CB 3.89Å; V55-I118 HydrophobicContact CG2-CD1 3.83Å
56P97.5Very high97.2Very high16 Ų1619.7 Ų19.710%0.10412%0.121CC..Hα-helixtrans-65.5-3118021.6-30.8000113.1Q52 V58 L59 N60 R75 V76Q52-P56 VanDerWaalsContact O-CD 3.24Å; Q52-P56 WeakPolarHBondContact O-CD 3.4Å; Q52-P56 VanDerWaalsContact O-CG 3.22Å; Q52-P56 WeakPolarHBondContact O-CG 3.07Å; P56-V58 VanDerWaalsContact C-N 3.33Å; P56-L59 PolarHBondContact O-N 2.9Å; P56-N60 WeakPolarHBondContact O-CB 3.23Å; P56-N60 PolarHBondContact O-N 3.04Å; P56-N60 PolarHBondContact O-OD1 3.1Å; P56-R75 HydrophobicContact CB-CG 4.37Å; P56-R75 HydrophobicContact CG-CG 4.26Å; P56-V76 HydrophobicContact CG-CG2 3.88Å
57L98Very high97.1Very high0 Ų019.7 Ų19.70%012%0.121CC..Hα-helixtrans-65.6-38171.5-66.2178.9000111.5E53 I54 V55 N60 G61 G62 D63 L64 V67 V215E53-L57 WeakPolarHBondContact O-CG 3.22Å; I54-L57 WeakPolarHBondContact O-CB 3.3Å; I54-L57 PolarHBondContact O-N 3.5Å; I54-L57 VanDerWaalsContact O-N 3.1Å; V55-L57 VanDerWaalsContact C-N 3.29Å; V55-L57 PolarHBondContact O-N 3.35Å; L57-N60 WeakPolarHBondContact CA-OD1 3.37Å; L57-N60 PolarHBondContact O-OD1 2.97Å; L57-N60 VanDerWaalsContact O-OD1 3.06Å; L57-G61 PolarHBondContact O-N 2.95Å; L57-G62 WeakPolarHBondContact O-CA 3.41Å; L57-G62 PolarHBondContact O-N 2.74Å; L57-D63 WeakPolarHBondContact CD2-O 3.42Å; L57-L64 HydrophobicContact CD1-CD2 4.05Å; L57-L64 HydrophobicContact CD2-CD2 3.79Å; L57-V67 HydrophobicContact CD1-CG1 4.19Å; L57-V67 HydrophobicContact CD1-CG2 4.43Å; L57-V67 HydrophobicContact CD2-CG1 3.82Å; L57-V67 HydrophobicContact CD2-CG2 3.92Å; L57-V67 HydrophobicContact CG-CG1 3.82Å; L57-V215 HydrophobicContact CB-CG1 4Å; L57-V215 HydrophobicContact CB-CG2 4.06Å; L57-V215 HydrophobicContact CD1-CG1 3.98Å; L57-V215 HydrophobicContact CD1-CG2 4.46Å
58V98.1Very high97.2Very high1 Ų124 Ų241%0.00614%0.137CC..Hα-helixtrans-66.2-41.9174.6178.10000110.9I54 V55 P56 L196 L203 R205 L207I54-V58 HydrophobicContact CG2-CG2 3.98Å; I54-V58 WeakPolarHBondContact O-CG2 3.05Å; I54-V58 PolarHBondContact O-N 2.91Å; V55-V58 PolarHBondContact O-N 3.26Å; P56-V58 VanDerWaalsContact C-N 3.33Å; V58-L196 HydrophobicContact CG2-CD2 4.02Å; V58-L203 HydrophobicContact CB-CD1 4.29Å; V58-L203 HydrophobicContact CG1-CD1 3.81Å; V58-R205 HydrophobicContact CG1-CB 4.38Å; V58-R205 HydrophobicContact CG1-CG 4.31Å; V58-R205 WeakPolarHBondContact O-CG 3.28Å; V58-L207 HydrophobicContact CB-CD1 4.48Å; V58-L207 HydrophobicContact CG1-CD1 4.27Å; V58-L207 HydrophobicContact CG2-CD1 4.47Å
59L97.3Very high97.1Very high28 Ų2827.8 Ų27.815%0.14716%0.16CC..Hα-helixtrans-69.6-33-177.9-67.6175.3000113.8I38 V55 P56 P94 A96 L203I38-L59 HydrophobicContact CG1-CD1 4.37Å; I38-L59 HydrophobicContact CG1-CD2 4.35Å; V55-L59 HydrophobicContact CG1-CD1 3.78Å; V55-L59 HydrophobicContact CG1-CG 4.21Å; V55-L59 WeakPolarHBondContact O-CG 3.36Å; V55-L59 PolarHBondContact O-N 3.17Å; P56-L59 PolarHBondContact O-N 2.9Å; L59-P94 HydrophobicContact CD1-CG 4.25Å; L59-P94 HydrophobicContact CD2-CG 3.91Å; L59-A96 HydrophobicContact CD1-CB 4.01Å; L59-L203 HydrophobicContact CD2-CD1 4.11Å
60N96.2Very high97.1Very high59 Ų5930.6 Ų30.632%0.31618%0.175SC..THydrogen-bonded Turntrans-99.97-174.2780.7000114.8P56 L57 G62 D63P56-N60 WeakPolarHBondContact O-CB 3.23Å; P56-N60 PolarHBondContact O-N 3.04Å; P56-N60 PolarHBondContact O-OD1 3.1Å; L57-N60 WeakPolarHBondContact CA-OD1 3.37Å; L57-N60 PolarHBondContact O-OD1 2.97Å; L57-N60 VanDerWaalsContact O-OD1 3.06Å; N60-G62 PolarHBondContact OD1-N 3.41Å; N60-D63 PolarHBondContact ND2-O 3.01Å; N60-D63 PolarHBondContact OD1-N 3.46Å
61G96.4Very high97.1Very high34 Ų3430.6 Ų30.635%0.35118%0.178SC..THydrogen-bonded Turntrans80.423.3-178.900000114.5L57 T211 R214L57-G61 PolarHBondContact O-N 2.95Å; G61-T211 VanDerWaalsContact O-CG2 3.3Å; G61-T211 WeakPolarHBondContact O-CG2 3.19Å; G61-R214 PolarHBondContact O-NH2 3.37Å
62G96.8Very high97Very high0 Ų030.6 Ų30.60%018%0.178CC..SBendtrans77.225.7177.200000113.8L57 N60 L64 R214L57-G62 WeakPolarHBondContact O-CA 3.41Å; L57-G62 PolarHBondContact O-N 2.74Å; N60-G62 PolarHBondContact OD1-N 3.41Å; G62-L64 PolarHBondContact O-N 3.08Å; G62-R214 PolarHBondContact O-NH2 3.1Å
63D96.7Very high96.9Very high74 Ų7433 Ų3340%0.39619%0.186SC..  trans-73.7116.8170.7172.518.4000109.5L57 N60 T65 P66L57-D63 WeakPolarHBondContact CD2-O 3.42Å; N60-D63 PolarHBondContact ND2-O 3.01Å; N60-D63 PolarHBondContact OD1-N 3.46Å; D63-T65 VanDerWaalsContact C-N 3.26Å; D63-T65 PolarHBondContact O-N 3.47Å; D63-T65 VanDerWaalsContact OD1-CB 3.29Å; D63-T65 WeakPolarHBondContact OD1-CB 3.31Å; D63-T65 PolarHBondContact OD1-N 3.34Å; D63-T65 PolarHBondContact OD1-OG1 2.85Å; D63-P66 VanDerWaalsContact O-CD 3.32Å; D63-P66 WeakPolarHBondContact O-CD 3.5Å
64L96.5Very high96.9Very high38 Ų3834.5 Ų34.520%0.19919%0.194CC..  trans-76.3-11.2-177.1-57.3-177.5000113.3L57 G62 V67 Q68 H218L57-L64 HydrophobicContact CD1-CD2 4.05Å; L57-L64 HydrophobicContact CD2-CD2 3.79Å; G62-L64 PolarHBondContact O-N 3.08Å; L64-V67 HydrophobicContact CB-CG2 4.18Å; L64-V67 HydrophobicContact CD2-CG2 4.29Å; L64-V67 WeakPolarHBondContact O-CG2 3.14Å; L64-V67 PolarHBondContact O-N 3.35Å; L64-Q68 HydrophobicContact CB-CG 4.43Å; L64-Q68 WeakPolarHBondContact O-CB 3.3Å; L64-Q68 WeakPolarHBondContact O-CG 3.41Å; L64-Q68 PolarHBondContact O-N 2.95Å; L64-Q68 VanDerWaalsContact O-N 3.08Å; L64-H218 HydrophobicContact CD2-CB 3.96Å
65T96.5Very high96.8Very high75 Ų7535.2 Ų35.246%0.4620%0.197SC..Hα-helixtrans-54.4-48.9-174.2-52.70000112.7D63 V67 Q68 T69D63-T65 VanDerWaalsContact C-N 3.26Å; D63-T65 PolarHBondContact O-N 3.47Å; D63-T65 VanDerWaalsContact OD1-CB 3.29Å; D63-T65 WeakPolarHBondContact OD1-CB 3.31Å; D63-T65 PolarHBondContact OD1-N 3.34Å; D63-T65 PolarHBondContact OD1-OG1 2.85Å; T65-V67 PolarHBondContact O-N 3.04Å; T65-Q68 PolarHBondContact O-N 3.26Å; T65-T69 HydrophobicContact CG2-CG2 4.43Å; T65-T69 WeakPolarHBondContact O-CB 3.41Å; T65-T69 WeakPolarHBondContact O-CG2 3.48Å; T65-T69 PolarHBondContact O-N 3.45Å; T65-T69 VanDerWaalsContact O-N 3.15Å; T65-T69 PolarHBondContact O-OG1 2.98Å
66P94.8Very high96.8Very high33 Ų3335.2 Ų35.221%0.21420%0.197CC..Hα-helixtrans-67.2-37.9-178.4-21.535.9000113D63 Q68 T69 I70D63-P66 VanDerWaalsContact O-CD 3.32Å; D63-P66 WeakPolarHBondContact O-CD 3.5Å; P66-Q68 VanDerWaalsContact C-N 3.26Å; P66-Q68 PolarHBondContact O-N 3.11Å; P66-T69 PolarHBondContact O-N 2.87Å; P66-I70 HydrophobicContact CB-CD1 4.45Å; P66-I70 WeakPolarHBondContact O-CB 3.5Å; P66-I70 PolarHBondContact O-N 3.06Å
67V96.5Very high96.8Very high0 Ų034.4 Ų34.40%019%0.192CC..Hα-helixtrans-71.1-22.5179.7-63.50000112.7E53 L57 L64 T65 N227 M229E53-V67 HydrophobicContact CG-CG1 4.37Å; L57-V67 HydrophobicContact CD1-CG1 4.19Å; L57-V67 HydrophobicContact CD1-CG2 4.43Å; L57-V67 HydrophobicContact CD2-CG1 3.82Å; L57-V67 HydrophobicContact CD2-CG2 3.92Å; L57-V67 HydrophobicContact CG-CG1 3.82Å; L64-V67 HydrophobicContact CB-CG2 4.18Å; L64-V67 HydrophobicContact CD2-CG2 4.29Å; L64-V67 WeakPolarHBondContact O-CG2 3.14Å; L64-V67 PolarHBondContact O-N 3.35Å; T65-V67 PolarHBondContact O-N 3.04Å; V67-N227 PolarHBondContact O-ND2 3.36Å; V67-M229 VanDerWaalsContact O-CB 3.31Å; V67-M229 WeakPolarHBondContact O-CB 3.28Å
68Q96.4Very high96.8Very high102 Ų10235.2 Ų35.248%0.47720%0.195SC..Hα-helixtrans-93.5-15.4179.5-70.6175.8-16.500113.5L64 T65 P66 M229L64-Q68 HydrophobicContact CB-CG 4.43Å; L64-Q68 WeakPolarHBondContact O-CB 3.3Å; L64-Q68 WeakPolarHBondContact O-CG 3.41Å; L64-Q68 PolarHBondContact O-N 2.95Å; L64-Q68 VanDerWaalsContact O-N 3.08Å; T65-Q68 PolarHBondContact O-N 3.26Å; P66-Q68 VanDerWaalsContact C-N 3.26Å; P66-Q68 PolarHBondContact O-N 3.11Å; Q68-M229 WeakPolarHBondContact O-CG 3.23Å
69T96.8Very high96.8Very high87 Ų8735.4 Ų35.453%0.53420%0.196SC..Hα-helixtrans-121.4-20.6-172.458.80000114.5T65 P66T65-T69 HydrophobicContact CG2-CG2 4.43Å; T65-T69 WeakPolarHBondContact O-CB 3.41Å; T65-T69 WeakPolarHBondContact O-CG2 3.48Å; T65-T69 PolarHBondContact O-N 3.45Å; T65-T69 VanDerWaalsContact O-N 3.15Å; T65-T69 PolarHBondContact O-OG1 2.98Å; P66-T69 PolarHBondContact O-N 2.87Å
70I96.8Very high96.9Very high71 Ų7134 Ų3436%0.36419%0.189SC..SBendtrans-120.3125.5-176.3-53.7173.8000109.1P66 D74 R75P66-I70 HydrophobicContact CB-CD1 4.45Å; P66-I70 WeakPolarHBondContact O-CB 3.5Å; P66-I70 PolarHBondContact O-N 3.06Å; I70-D74 HydrophobicContact CG2-CB 3.65Å; I70-R75 HydrophobicContact CB-CB 4.39Å; I70-R75 HydrophobicContact CG2-CB 3.95Å
71P97.3Very high97Very high23 Ų2332.7 Ų32.715%0.14918%0.181CC..  trans-53.3144175-25.534.1000112.3W73 D74 R75 M229 L234P71-W73 VanDerWaalsContact C-N 3.26Å; P71-W73 HydrophobicContact CB-CD2 4Å; P71-W73 VanDerWaalsContact CB-CE2 3.47Å; P71-W73 HydrophobicContact CB-CG 4.37Å; P71-W73 HydrophobicContact CB-CH2 4.38Å; P71-W73 HydrophobicContact CB-CZ2 3.71Å; P71-W73 HydrophobicContact CG-CZ2 4.32Å; P71-W73 PolarHBondContact O-N 3.47Å; P71-D74 WeakPolarHBondContact O-CB 3.37Å; P71-D74 PolarHBondContact O-N 2.87Å; P71-R75 PolarHBondContact O-N 3.01Å; P71-M229 CarbonylContact C-O 3.55Å; P71-M229 WeakPolarHBondContact CA-O 3.33Å; P71-M229 HydrophobicContact CG-SD 3.89Å; P71-L234 HydrophobicContact CG-CD1 4.13Å
72N96.2Very high97.1Very high0 Ų034 Ų340%018%0.182CC..Hα-helixtrans-55.4-38.3-177.864-47.4000113.2Q52 D74 R75 V76 M229 Y232Q52-N72 HydrophobicContact CB-CB 4.16Å; Q52-N72 PolarHBondContact OE1-ND2 2.91Å; N72-D74 VanDerWaalsContact C-N 3.26Å; N72-D74 PolarHBondContact O-N 3.06Å; N72-R75 PolarHBondContact O-N 2.82Å; N72-V76 CarbonylContact O-C 3.57Å; N72-V76 PolarHBondContact O-N 2.87Å; N72-M229 PolarHBondContact N-O 2.62Å; N72-M229 PolarHBondContact OD1-O 2.91Å; N72-Y232 WeakPolarHBondContact ND2-CE2 3.3Å; N72-Y232 PolarHBondContact ND2-OH 2.6Å
73W96.1Very high97.1Very high49 Ų4938.5 Ų38.519%0.18620%0.199CC..Hα-helixtrans-70.7-15177.153.577000114.7P71 P77 W78 Y232 L234 V235P71-W73 VanDerWaalsContact C-N 3.26Å; P71-W73 HydrophobicContact CB-CD2 4Å; P71-W73 VanDerWaalsContact CB-CE2 3.47Å; P71-W73 HydrophobicContact CB-CG 4.37Å; P71-W73 HydrophobicContact CB-CH2 4.38Å; P71-W73 HydrophobicContact CB-CZ2 3.71Å; P71-W73 HydrophobicContact CG-CZ2 4.32Å; P71-W73 PolarHBondContact O-N 3.47Å; W73-P77 WeakPolarHBondContact O-CA 3.13Å; W73-P77 WeakPolarHBondContact O-CB 3.26Å; W73-W78 HydrophobicContact CB-CZ3 4.03Å; W73-Y232 HydrophobicContact CE3-CD1 4.1Å; W73-Y232 AromaticContact CE3-CE1 3.79Å; W73-Y232 HydrophobicContact CE3-CE1 3.79Å; W73-Y232 AromaticContact CZ3-CD1 3.58Å; W73-Y232 HydrophobicContact CZ3-CD1 3.58Å; W73-Y232 AromaticContact CZ3-CE1 3.77Å; W73-Y232 HydrophobicContact CZ3-CE1 3.77Å; W73-Y232 AromaticContact CZ3-CG 3.99Å; W73-Y232 HydrophobicContact CZ3-CG 3.99Å; W73-L234 HydrophobicContact CH2-CB 4.1Å; W73-L234 HydrophobicContact CZ2-CB 4.28Å; W73-V235 HydrophobicContact CH2-CG2 3.7Å; W73-V235 HydrophobicContact CZ2-CG2 4.45Å; W73-V235 HydrophobicContact CZ3-CG2 3.92Å
74D97Very high97.1Very high32 Ų3235 Ų3517%0.17118%0.18CC..Hα-helixtrans-93.5-35.8172.8-73.7-5.9000111.8I70 P71 N72 R83I70-D74 HydrophobicContact CG2-CB 3.65Å; P71-D74 WeakPolarHBondContact O-CB 3.37Å; P71-D74 PolarHBondContact O-N 2.87Å; N72-D74 VanDerWaalsContact C-N 3.26Å; N72-D74 PolarHBondContact O-N 3.06Å; D74-R83 IonicContact OD1-CZ 2.61Å; D74-R83 IonicContact OD1-NE 3.53Å; D74-R83 PolarHBondContact OD1-NE 2.84Å; D74-R83 IonicContact OD1-NH2 2.7Å; D74-R83 PolarHBondContact OD1-NH2 2.94Å; D74-R83 IonicContact OD2-CZ 3.62Å; D74-R83 IonicContact OD2-NH2 3.55Å; D74-R83 PolarHBondContact OD2-NH2 2.75Å
75R96.1Very high97Very high16 Ų1635.2 Ų35.26%0.0619%0.188CC..Hα-helixtrans-78.4-37.6-176.5-178.5164.947.390.4-1.4112.8Q52 E53 P56 I70 P71 N72Q52-R75 PolarHBondContact O-NH1 2.85Å; E53-R75 IonicContact OE2-CZ 3.72Å; E53-R75 IonicContact OE2-NH1 3.93Å; E53-R75 IonicContact OE2-NH2 2.82Å; E53-R75 PolarHBondContact OE2-NH2 2.98Å; P56-R75 HydrophobicContact CB-CG 4.37Å; P56-R75 HydrophobicContact CG-CG 4.26Å; I70-R75 HydrophobicContact CB-CB 4.39Å; I70-R75 HydrophobicContact CG2-CB 3.95Å; P71-R75 PolarHBondContact O-N 3.01Å; N72-R75 PolarHBondContact O-N 2.82Å
76V98.1Very high97Very high1 Ų136 Ų361%0.00619%0.188CC..SBendtrans-140.375.8179.5-1720000107.9Q52 P56 N72 A96 V98Q52-V76 HydrophobicContact CB-CB 4.18Å; Q52-V76 HydrophobicContact CB-CG2 4.45Å; Q52-V76 HydrophobicContact CG-CB 3.95Å; Q52-V76 HydrophobicContact CG-CG1 4.05Å; Q52-V76 PolarHBondContact NE2-O 3.3Å; P56-V76 HydrophobicContact CG-CG2 3.88Å; N72-V76 CarbonylContact O-C 3.57Å; N72-V76 PolarHBondContact O-N 2.87Å; V76-A96 HydrophobicContact CG1-CB 4.16Å; V76-A96 HydrophobicContact CG2-CB 4.21Å; V76-V98 HydrophobicContact CG1-CG1 3.86Å
77P98.2Very high97.1Very high0 Ų035.4 Ų35.40%018%0.184CC..  trans-68.3157.3-172.431.1-39.3000112.8W73 A84 V87 L88 L91 M97 V98W73-P77 WeakPolarHBondContact O-CA 3.13Å; W73-P77 WeakPolarHBondContact O-CB 3.26Å; P77-A84 HydrophobicContact CB-CB 4.22Å; P77-V87 HydrophobicContact CB-CG2 3.8Å; P77-V87 HydrophobicContact CG-CG2 3.75Å; P77-L88 HydrophobicContact CG-CB 4.32Å; P77-L88 HydrophobicContact CG-CD1 4.03Å; P77-L91 HydrophobicContact CG-CD1 4.38Å; P77-M97 WeakPolarHBondContact O-CA 3.46Å; P77-V98 WeakPolarHBondContact O-CG2 3.33Å; P77-V98 PolarHBondContact O-N 3.07Å
78W98.7Very high97Very high17 Ų1735.4 Ų35.46%0.06418%0.184CC..BIsolated β-bridgetrans-75.5123.8165.7-78-98.4000110.4T48 Q52 W73 E80 E81 A84 V98 H100 Y232T48-W78 HydrophobicContact CG2-CZ2 3.84Å; Q52-W78 VanDerWaalsContact CD-CH2 3.42Å; W73-W78 HydrophobicContact CB-CZ3 4.03Å; W78-E80 VanDerWaalsContact C-N 3.26Å; W78-E80 PolarHBondContact O-N 2.89Å; W78-E81 HydrophobicContact CB-CB 3.88Å; W78-E81 HydrophobicContact CB-CG 3.58Å; W78-E81 HydrophobicContact CG-CG 4.28Å; W78-E81 PolarHBondContact O-N 3.38Å; W78-E81 VanDerWaalsContact O-N 3.11Å; W78-A84 VanDerWaalsContact O-CB 3.23Å; W78-A84 WeakPolarHBondContact O-CB 3.43Å; W78-V98 CarbonylContact C-O 3.53Å; W78-V98 VanDerWaalsContact CA-O 3.31Å; W78-V98 WeakPolarHBondContact CA-O 3.23Å; W78-V98 HydrophobicContact CB-CG2 4.3Å; W78-V98 HydrophobicContact CD2-CG2 3.51Å; W78-V98 HydrophobicContact CE3-CG2 4.12Å; W78-V98 HydrophobicContact CG-CG2 3.61Å; W78-V98 HydrophobicContact CZ2-CG2 4.09Å; W78-H100 AromaticContact CD1-CD2 3.61Å; W78-H100 AromaticContact CD1-NE2 3.89Å; W78-H100 AromaticContact CE2-NE2 4Å; W78-H100 AromaticContact NE1-CD2 3.28Å; W78-H100 PolarHBondContact NE1-CD2 3.23Å; W78-H100 VanDerWaalsContact NE1-CD2 3.28Å; W78-H100 AromaticContact NE1-CE1 3.8Å; W78-H100 AromaticContact NE1-NE2 3.05Å; W78-H100 PolarHBondContact NE1-NE2 3.05Å; W78-Y232 WeakPolarHBondContact CH2-OH 3.42Å
79L98.4Very high96.7Very high4 Ų436 Ų362%0.02119%0.191CC..THydrogen-bonded Turntrans-53.8-45.2-176.6177.965.1000112.4A28 I31 F39 E81 L88 M97 V98 P107A28-L79 HydrophobicContact CB-CD1 4.46Å; A28-L79 HydrophobicContact CB-CD2 4.44Å; A28-L79 HydrophobicContact CB-CG 3.91Å; A28-L79 WeakPolarHBondContact CB-O 3.38Å; I31-L79 HydrophobicContact CD1-CD1 3.79Å; I31-L79 HydrophobicContact CG2-CD1 4.13Å; F39-L79 HydrophobicContact CE1-CD2 4.17Å; L79-E81 VanDerWaalsContact C-N 3.31Å; L79-E81 PolarHBondContact O-N 3.48Å; L79-L88 HydrophobicContact CD1-CD2 4.06Å; L79-M97 HydrophobicContact CD1-SD 4.05Å; L79-V98 PolarHBondContact N-O 3.01Å; L79-P107 HydrophobicContact CD2-CG 4.05Å
80E98.3Very high96.5Very high0 Ų042 Ų420%020%0.203CC..THydrogen-bonded Turntrans-77.5-9.4-176.361.8-89.2-159.300114.9H20 S24 F25 W78 S99 H100 M101 F161H20-E80 PolarHBondContact CD2-O 3.4Å; H20-E80 WeakPolarHBondContact NE2-CG 3.35Å; S24-E80 WeakPolarHBondContact CB-O 2.97Å; S24-E80 PolarHBondContact OG-O 3.48Å; F25-E80 HydrophobicContact CD1-CB 4.39Å; F25-E80 HydrophobicContact CE1-CB 4.3Å; W78-E80 VanDerWaalsContact C-N 3.26Å; W78-E80 PolarHBondContact O-N 2.89Å; E80-S99 WeakPolarHBondContact OE2-CA 3.4Å; E80-S99 VanDerWaalsContact OE2-CB 3.3Å; E80-S99 WeakPolarHBondContact OE2-CB 3.5Å; E80-S99 PolarHBondContact OE2-OG 3.39Å; E80-H100 WeakPolarHBondContact OE1-CB 3.5Å; E80-H100 PolarHBondContact OE1-N 2.89Å; E80-M101 HydrophobicContact CB-CE 3.41Å; E80-M101 VanDerWaalsContact CB-CE 3.41Å; E80-M101 HydrophobicContact CB-CG 4.26Å; E80-M101 HydrophobicContact CG-CE 3.84Å; E80-M101 HydrophobicContact CG-CG 4.45Å; E80-F161 HydrophobicContact CG-CE1 4.41Å; E80-F161 HydrophobicContact CG-CZ 4.4Å
81E98.3Very high96.4Very high30 Ų3040.5 Ų40.514%0.1420%0.196CC..SBendtrans-92.4154.2-176.6-70.6-167.915900112.6T19 H20 S24 W78 L79 R83 A84T19-E81 VanDerWaalsContact CB-CD 3.5Å; T19-E81 VanDerWaalsContact CB-OE1 3.24Å; T19-E81 WeakPolarHBondContact CB-OE1 3.47Å; T19-E81 WeakPolarHBondContact O-CA 3.5Å; T19-E81 PolarHBondContact OG1-OE1 3.27Å; H20-E81 IonicContact CE1-OE1 3.93Å; S24-E81 VanDerWaalsContact CB-C 3.49Å; W78-E81 HydrophobicContact CB-CB 3.88Å; W78-E81 HydrophobicContact CB-CG 3.58Å; W78-E81 HydrophobicContact CG-CG 4.28Å; W78-E81 PolarHBondContact O-N 3.38Å; W78-E81 VanDerWaalsContact O-N 3.11Å; L79-E81 VanDerWaalsContact C-N 3.31Å; L79-E81 PolarHBondContact O-N 3.48Å; E81-R83 PolarHBondContact O-N 2.95Å; E81-A84 PolarHBondContact O-N 3.49Å
82T97.9Very high96.2Very high62 Ų6244.6 Ų44.638%0.3822%0.222SC..THydrogen-bonded Turntrans-55.7-27.3179.6-54.30000112.1T19 S21T19-T82 PolarHBondContact O-N 3.44Å; T19-T82 PolarHBondContact O-OG1 2.94Å; T19-T82 VanDerWaalsContact O-OG1 3.06Å; S21-T82 PolarHBondContact OG-OG1 3.46Å
83R96.8Very high96.1Very high95 Ų9548.1 Ų48.136%0.35825%0.247SC..THydrogen-bonded Turntrans-67.1-34.7179.4-165.959.4173.4-171.6-1.7113.1D74 E81 A85 L86 V87D74-R83 IonicContact OD1-CZ 2.61Å; D74-R83 IonicContact OD1-NE 3.53Å; D74-R83 PolarHBondContact OD1-NE 2.84Å; D74-R83 IonicContact OD1-NH2 2.7Å; D74-R83 PolarHBondContact OD1-NH2 2.94Å; D74-R83 IonicContact OD2-CZ 3.62Å; D74-R83 IonicContact OD2-NH2 3.55Å; D74-R83 PolarHBondContact OD2-NH2 2.75Å; E81-R83 PolarHBondContact O-N 2.95Å; R83-A85 VanDerWaalsContact C-N 3.34Å; R83-A85 PolarHBondContact O-N 3.33Å; R83-L86 WeakPolarHBondContact O-CB 3.37Å; R83-L86 PolarHBondContact O-N 2.91Å; R83-V87 PolarHBondContact O-N 3.35Å
84A97.3Very high96.1Very high0 Ų047.3 Ų47.30%025%0.248CC..Hα-helixtrans-58.7-44.6-177.500000112.3Y27 P77 W78 E81 L86 V87 L88Y27-A84 HydrophobicContact CD1-CB 4.36Å; Y27-A84 HydrophobicContact CE1-CB 3.95Å; P77-A84 HydrophobicContact CB-CB 4.22Å; W78-A84 VanDerWaalsContact O-CB 3.23Å; W78-A84 WeakPolarHBondContact O-CB 3.43Å; E81-A84 PolarHBondContact O-N 3.49Å; A84-L86 PolarHBondContact O-N 3.2Å; A84-V87 PolarHBondContact O-N 2.92Å; A84-V87 VanDerWaalsContact O-N 3.1Å; A84-L88 HydrophobicContact CB-CB 4.47Å; A84-L88 HydrophobicContact CB-CD2 4.37Å; A84-L88 WeakPolarHBondContact O-CB 3.47Å; A84-L88 PolarHBondContact O-N 2.95Å
85A95.1Very high96.1Very high43 Ų4346.4 Ų46.436%0.35524%0.243SC..Hα-helixtrans-58.3-20178.100000114Y27 R83Y27-A85 HydrophobicContact CD1-CB 3.96Å; Y27-A85 HydrophobicContact CD2-CB 3.82Å; Y27-A85 HydrophobicContact CE1-CB 4.29Å; Y27-A85 HydrophobicContact CE2-CB 4.17Å; Y27-A85 HydrophobicContact CG-CB 3.72Å; R83-A85 VanDerWaalsContact C-N 3.34Å; R83-A85 PolarHBondContact O-N 3.33Å
86L95.5Very high96.2Very high91 Ų9146 Ų4648%0.47624%0.243SC..Hα-helixtrans-92.2-26.7-179.5-57.8178.8000113.3R83 A84 R90R83-L86 WeakPolarHBondContact O-CB 3.37Å; R83-L86 PolarHBondContact O-N 2.91Å; A84-L86 PolarHBondContact O-N 3.2Å; L86-R90 PolarHBondContact O-NE 3.4Å
87V96.4Very high96.2Very high21 Ų2146 Ų4613%0.12724%0.243CC..Hα-helixtrans-123.6-32-166.1-53.80000113.8P77 R83 A84 D89 R90 L91P77-V87 HydrophobicContact CB-CG2 3.8Å; P77-V87 HydrophobicContact CG-CG2 3.75Å; R83-V87 PolarHBondContact O-N 3.35Å; A84-V87 PolarHBondContact O-N 2.92Å; A84-V87 VanDerWaalsContact O-N 3.1Å; V87-D89 PolarHBondContact O-N 3.28Å; V87-R90 WeakPolarHBondContact O-CB 3.28Å; V87-R90 PolarHBondContact O-N 2.96Å; V87-L91 PolarHBondContact O-N 2.82Å
88L94.7Very high96.2Very high0 Ų046 Ų460%024%0.243CC..G310 helixtrans-66.4-38.8-166.3-173.356.2000112.8Y27 I31 P77 L79 A84 R90 L91 R95 M97Y27-L88 HydrophobicContact CE1-CD2 4.34Å; I31-L88 HydrophobicContact CD1-CD2 3.29Å; I31-L88 HydrophobicContact CD1-CG 4.18Å; P77-L88 HydrophobicContact CG-CB 4.32Å; P77-L88 HydrophobicContact CG-CD1 4.03Å; L79-L88 HydrophobicContact CD1-CD2 4.06Å; A84-L88 HydrophobicContact CB-CB 4.47Å; A84-L88 HydrophobicContact CB-CD2 4.37Å; A84-L88 WeakPolarHBondContact O-CB 3.47Å; A84-L88 PolarHBondContact O-N 2.95Å; L88-R90 PolarHBondContact O-N 3.36Å; L88-L91 HydrophobicContact CD1-CD1 3.92Å; L88-L91 PolarHBondContact O-N 3.46Å; L88-R95 HydrophobicContact CD1-CB 4.21Å; L88-M97 HydrophobicContact CD1-CB 4.27Å; L88-M97 HydrophobicContact CD1-CE 3.87Å; L88-M97 HydrophobicContact CD1-SD 4.34Å; L88-M97 HydrophobicContact CD2-CE 4.14Å; L88-M97 HydrophobicContact CD2-SD 3.83Å; L88-M97 HydrophobicContact CG-CE 4.46Å
89D90.5Very high96.2Very high114 Ų11445.2 Ų45.261%0.6124%0.24SC*.G310 helixtrans-68.4-11.2175.6-65.1-10000113.5Y27 V87Y27-D89 PolarHBondContact OH-OD1 2.88Å; V87-D89 PolarHBondContact O-N 3.28Å
90R93.1Very high96.2Very high213 Ų21346 Ų4680%0.80424%0.243SC*.G310 helixtrans-102.1-8.2179.1-54.7178-175177.33.5112.6L86 V87 L88L86-R90 PolarHBondContact O-NE 3.4Å; V87-R90 WeakPolarHBondContact O-CB 3.28Å; V87-R90 PolarHBondContact O-N 2.96Å; L88-R90 PolarHBondContact O-N 3.36Å
91L94.2Very high96.2Very high40 Ų4046.3 Ų46.321%0.20925%0.245CC..SBendtrans-74.1140.5178.4-64.8-174.6000110.2P77 V87 L88 R95P77-L91 HydrophobicContact CG-CD1 4.38Å; V87-L91 PolarHBondContact O-N 2.82Å; L88-L91 HydrophobicContact CD1-CD1 3.92Å; L88-L91 PolarHBondContact O-N 3.46Å; L91-R95 HydrophobicContact CB-CG 4.24Å
92P92.7Very high96.2Very high108 Ų10845.3 Ų45.370%0.70124%0.241SC*.PPolyproline II helixtrans-68.8145.4173.430-34.3000110.6P94P92-P94 CarbonylContact O-C 3.3Å; P92-P94 VanDerWaalsContact O-C 3.3Å
93S93.7Very high96.3Very high74 Ų7443.7 Ų43.752%0.51723%0.228SC..SBendtrans-71.4142.9171.5-51.80000110.9E34E34-S93 PolarHBondContact OE2-OG 3.22Å
94P96.3Very high96.3Very high33 Ų3345.3 Ų45.321%0.21424%0.239CC..SBendcis-70.6132.3-529.8-34.6000111.9E36 I38 L59 P92 R205E36-P94 HydrophobicContact CB-CB 4.16Å; E36-P94 WeakPolarHBondContact O-CB 3.5Å; I38-P94 HydrophobicContact CG1-CB 4.34Å; L59-P94 HydrophobicContact CD1-CG 4.25Å; L59-P94 HydrophobicContact CD2-CG 3.91Å; P92-P94 CarbonylContact O-C 3.3Å; P92-P94 VanDerWaalsContact O-C 3.3Å; P94-R205 VanDerWaalsContact CG-NH2 3.26Å
95R97.6Very high96.3Very high13 Ų1346.5 Ų46.55%0.04925%0.245CC..PPolyproline II helixtrans-75.6133.5176.6-51.8177.9-64.6-177.9-3.8108.5K32 D37 I38 L88 L91 M97K32-R95 PolarHBondContact O-NH2 3.38Å; D37-R95 WeakPolarHBondContact OD1-CB 3.33Å; D37-R95 IonicContact OD1-CZ 3.78Å; D37-R95 IonicContact OD1-NE 2.67Å; D37-R95 PolarHBondContact OD1-NE 3.14Å; D37-R95 IonicContact OD1-NH2 3.54Å; D37-R95 PolarHBondContact OD1-NH2 3.5Å; D37-R95 IonicContact OD2-CZ 3.72Å; D37-R95 IonicContact OD2-NE 2.86Å; D37-R95 IonicContact OD2-NH2 2.62Å; D37-R95 PolarHBondContact OD2-NH2 2.67Å; I38-R95 PolarHBondContact N-O 3.21Å; L88-R95 HydrophobicContact CD1-CB 4.21Å; L91-R95 HydrophobicContact CB-CG 4.24Å; R95-M97 HydrophobicContact CB-CE 4.09Å
96A98Very high96.5Very high8 Ų844.8 Ų44.87%0.06623%0.23CC..EExtended strand (participates in β ladder)trans-103.5129.2171.200000109V55 L59 V76V55-A96 HydrophobicContact CG1-CB 3.89Å; L59-A96 HydrophobicContact CD1-CB 4.01Å; V76-A96 HydrophobicContact CG1-CB 4.16Å; V76-A96 HydrophobicContact CG2-CB 4.21Å
97M98.4Very high96.6Very high1 Ų140.6 Ų40.61%0.00521%0.208CC..EExtended strand (participates in β ladder)trans-139.9159.3175.664.1-162.98900110.6D37 I38 F39 T40 P77 L79 L88 R95D37-M97 HydrophobicContact CB-CE 4.13Å; I38-M97 PolarHBondContact O-N 3.15Å; F39-M97 WeakPolarHBondContact CA-O 3.14Å; F39-M97 HydrophobicContact CD1-CG 3.66Å; F39-M97 HydrophobicContact CD1-SD 3.98Å; F39-M97 HydrophobicContact CE1-CE 4.33Å; F39-M97 HydrophobicContact CE1-CG 3.65Å; F39-M97 HydrophobicContact CE1-SD 3.3Å; F39-M97 WeakPolarHBondContact CE1-SD 3.44Å; F39-M97 HydrophobicContact CG-CG 4.34Å; F39-M97 HydrophobicContact CZ-CE 4.13Å; F39-M97 HydrophobicContact CZ-CG 4.31Å; F39-M97 HydrophobicContact CZ-SD 3.65Å; T40-M97 PolarHBondContact N-O 2.79Å; P77-M97 WeakPolarHBondContact O-CA 3.46Å; L79-M97 HydrophobicContact CD1-SD 4.05Å; L88-M97 HydrophobicContact CD1-CB 4.27Å; L88-M97 HydrophobicContact CD1-CE 3.87Å; L88-M97 HydrophobicContact CD1-SD 4.34Å; L88-M97 HydrophobicContact CD2-CE 4.14Å; L88-M97 HydrophobicContact CD2-SD 3.83Å; L88-M97 HydrophobicContact CG-CE 4.46Å; R95-M97 HydrophobicContact CB-CE 4.09Å
98V98.8Very high96.7Very high0 Ų044 Ų440%023%0.231CC..EExtended strand (participates in β ladder)trans-113.2159.9174.1-72.40000110.8T40 T48 Q52 V76 P77 W78 L79T40-V98 HydrophobicContact CG2-CG1 4.09Å; T40-V98 CarbonylContact O-C 3.56Å; T40-V98 WeakPolarHBondContact O-CA 3.36Å; T48-V98 HydrophobicContact CG2-CB 3.83Å; T48-V98 HydrophobicContact CG2-CG1 3.73Å; T48-V98 HydrophobicContact CG2-CG2 4.14Å; Q52-V98 HydrophobicContact CG-CG1 3.76Å; Q52-V98 HydrophobicContact CG-CG2 4.32Å; V76-V98 HydrophobicContact CG1-CG1 3.86Å; P77-V98 WeakPolarHBondContact O-CG2 3.33Å; P77-V98 PolarHBondContact O-N 3.07Å; W78-V98 CarbonylContact C-O 3.53Å; W78-V98 VanDerWaalsContact CA-O 3.31Å; W78-V98 WeakPolarHBondContact CA-O 3.23Å; W78-V98 HydrophobicContact CB-CG2 4.3Å; W78-V98 HydrophobicContact CD2-CG2 3.51Å; W78-V98 HydrophobicContact CE3-CG2 4.12Å; W78-V98 HydrophobicContact CG-CG2 3.61Å; W78-V98 HydrophobicContact CZ2-CG2 4.09Å; L79-V98 PolarHBondContact N-O 3.01Å
99S98.8Very high96.9Very high0 Ų045.7 Ų45.70%024%0.243CC..EExtended strand (participates in β ladder)trans-151.3153.8169.5-170.50000111.7T40 V41 T42 E80 M101T40-S99 PolarHBondContact O-N 3.48Å; V41-S99 WeakPolarHBondContact CA-O 3.37Å; V41-S99 WeakPolarHBondContact CG1-O 3.47Å; T42-S99 PolarHBondContact N-O 2.71Å; T42-S99 VanDerWaalsContact N-O 3.13Å; E80-S99 WeakPolarHBondContact OE2-CA 3.4Å; E80-S99 VanDerWaalsContact OE2-CB 3.3Å; E80-S99 WeakPolarHBondContact OE2-CB 3.5Å; E80-S99 PolarHBondContact OE2-OG 3.39Å; S99-M101 WeakPolarHBondContact OG-CB 3.22Å; S99-M101 PolarHBondContact OG-N 2.81Å
100H98.8Very high97.2Very high19 Ų1940.2 Ų40.29%0.08821%0.214CC..  trans-108.37.8167.8-66.8-45.6000112.7T42 P44 T48 W78 E80 F161 H167T42-H100 WeakPolarHBondContact O-CA 3.43Å; T42-H100 PolarHBondContact O-ND1 3.13Å; T42-H100 PolarHBondContact OG1-CE1 2.65Å; T42-H100 PolarHBondContact OG1-ND1 2.87Å; P44-H100 HydrophobicContact CG-CB 4.22Å; T48-H100 PolarHBondContact OG1-CE1 3.16Å; T48-H100 VanDerWaalsContact OG1-CE1 3.3Å; W78-H100 AromaticContact CD1-CD2 3.61Å; W78-H100 AromaticContact CD1-NE2 3.89Å; W78-H100 AromaticContact CE2-NE2 4Å; W78-H100 AromaticContact NE1-CD2 3.28Å; W78-H100 PolarHBondContact NE1-CD2 3.23Å; W78-H100 VanDerWaalsContact NE1-CD2 3.28Å; W78-H100 AromaticContact NE1-CE1 3.8Å; W78-H100 AromaticContact NE1-NE2 3.05Å; W78-H100 PolarHBondContact NE1-NE2 3.05Å; E80-H100 WeakPolarHBondContact OE1-CB 3.5Å; E80-H100 PolarHBondContact OE1-N 2.89Å; H100-F161 HydrophobicContact CB-CD1 3.64Å; H100-F161 HydrophobicContact CB-CD2 3.84Å; H100-F161 HydrophobicContact CB-CE1 3.55Å; H100-F161 HydrophobicContact CB-CE2 3.75Å; H100-F161 HydrophobicContact CB-CG 3.78Å; H100-F161 HydrophobicContact CB-CZ 3.6Å; H100-F161 VanDerWaalsContact O-CD1 3.23Å; H100-F161 WeakPolarHBondContact O-CD1 3.44Å; H100-H167 PolarHBondContact O-CD2 3.43Å; H100-H167 PolarHBondContact O-NE2 3.15Å
101M98.4Very high97.5Very high8 Ų834 Ų344%0.03919%0.192CC..  trans-74.3141-179.8-70.3-64178.100111.9Y10 L13 F25 E80 S99 L105 M106 F161 W171Y10-M101 HydrophobicContact CD1-CE 3.82Å; Y10-M101 HydrophobicContact CD1-SD 4.3Å; Y10-M101 HydrophobicContact CE1-CE 3.82Å; Y10-M101 HydrophobicContact CE1-SD 4.13Å; L13-M101 HydrophobicContact CD1-SD 4.49Å; F25-M101 HydrophobicContact CD1-CE 3.88Å; F25-M101 HydrophobicContact CE1-CE 3.58Å; E80-M101 HydrophobicContact CB-CE 3.41Å; E80-M101 VanDerWaalsContact CB-CE 3.41Å; E80-M101 HydrophobicContact CB-CG 4.26Å; E80-M101 HydrophobicContact CG-CE 3.84Å; E80-M101 HydrophobicContact CG-CG 4.45Å; S99-M101 WeakPolarHBondContact OG-CB 3.22Å; S99-M101 PolarHBondContact OG-N 2.81Å; M101-L105 HydrophobicContact CB-CB 4.48Å; M101-L105 HydrophobicContact SD-CB 4.44Å; M101-L105 HydrophobicContact SD-CD1 4.32Å; M101-M106 HydrophobicContact CB-SD 4.41Å; M101-F161 HydrophobicContact CE-CE1 4.2Å; M101-F161 HydrophobicContact SD-CE1 4.27Å; M101-W171 WeakPolarHBondContact O-CZ2 3.12Å; M101-W171 PolarHBondContact O-NE1 3.17Å
102P98.3Very high97.6Very high8 Ų837.2 Ų37.25%0.05222%0.216CC..  trans-67154.5168.331.1-35.6000110.4L13 H104 L105 S170L13-P102 HydrophobicContact CD1-CG 3.97Å; P102-H104 VanDerWaalsContact C-N 3.26Å; P102-H104 PolarHBondContact O-N 2.95Å; P102-H104 VanDerWaalsContact O-N 3.08Å; P102-L105 HydrophobicContact CG-CB 4.23Å; P102-L105 HydrophobicContact CG-CD1 3.7Å; P102-L105 HydrophobicContact CG-CG 3.9Å; P102-L105 PolarHBondContact O-N 2.79Å; P102-S170 WeakPolarHBondContact CB-OG 3.49Å
103Y98.4Very high97.9Very high29 Ų2932.5 Ų32.511%0.11419%0.185CC..G310 helixtrans-51.2-40.8-172.1175-96.3000114.4L105 M106 F110 F111 S170 W171 N173 L176Y103-L105 PolarHBondContact O-N 2.91Å; Y103-M106 WeakPolarHBondContact O-CB 3.33Å; Y103-M106 WeakPolarHBondContact O-CG 3.36Å; Y103-M106 PolarHBondContact O-N 3.06Å; Y103-F110 HydrophobicContact CD2-CE1 4.32Å; Y103-F110 AromaticContact CE2-CE1 3.89Å; Y103-F110 HydrophobicContact CE2-CE1 3.89Å; Y103-F111 HydrophobicContact CD1-CE1 4.4Å; Y103-F111 HydrophobicContact CE1-CD1 4.35Å; Y103-F111 AromaticContact CE1-CE1 3.79Å; Y103-F111 HydrophobicContact CE1-CE1 3.79Å; Y103-F111 HydrophobicContact CE2-CE1 4.29Å; Y103-F111 AromaticContact CZ-CD1 3.96Å; Y103-F111 AromaticContact CZ-CE1 3.74Å; Y103-S170 WeakPolarHBondContact CB-O 3.28Å; Y103-S170 PolarHBondContact N-OG 3.15Å; Y103-S170 VanDerWaalsContact N-OG 3.17Å; Y103-W171 HydrophobicContact CD2-CE3 4.02Å; Y103-W171 HydrophobicContact CD2-CH2 4.29Å; Y103-W171 AromaticContact CD2-CZ3 3.9Å; Y103-W171 HydrophobicContact CD2-CZ3 3.9Å; Y103-N173 HydrophobicContact CD2-CB 4.5Å; Y103-N173 HydrophobicContact CE1-CB 4.35Å; Y103-N173 WeakPolarHBondContact CE1-ND2 3.42Å; Y103-N173 HydrophobicContact CE2-CB 4.28Å; Y103-N173 VanDerWaalsContact CZ-ND2 3.27Å; Y103-N173 PolarHBondContact OH-ND2 3.24Å; Y103-L176 HydrophobicContact CD2-CD1 4.1Å; Y103-L176 HydrophobicContact CE2-CD1 3.82Å; Y103-L176 HydrophobicContact CE2-CD2 4.03Å; Y103-L176 HydrophobicContact CE2-CG 3.91Å
104H97.3Very high98.1Very high128 Ų12835.6 Ų35.659%0.59319%0.19SC*.G310 helixtrans-72.5-8-177.166.2-87.1000114.1P102P102-H104 VanDerWaalsContact C-N 3.26Å; P102-H104 PolarHBondContact O-N 2.95Å; P102-H104 VanDerWaalsContact O-N 3.08Å
105L97.8Very high98.2Very high25 Ų2534 Ų3413%0.13118%0.179CC..G310 helixtrans-107.36.8175.4-61-177.6000112.8Y10 H11 L13 M101 P102 Y103Y10-L105 HydrophobicContact CD1-CD1 4.39Å; Y10-L105 HydrophobicContact CE1-CD1 4.08Å; H11-L105 HydrophobicContact CB-CD1 3.78Å; H11-L105 HydrophobicContact CB-CD2 4Å; L13-L105 HydrophobicContact CD1-CD1 3.75Å; M101-L105 HydrophobicContact CB-CB 4.48Å; M101-L105 HydrophobicContact SD-CB 4.44Å; M101-L105 HydrophobicContact SD-CD1 4.32Å; P102-L105 HydrophobicContact CG-CB 4.23Å; P102-L105 HydrophobicContact CG-CD1 3.7Å; P102-L105 HydrophobicContact CG-CG 3.9Å; P102-L105 PolarHBondContact O-N 2.79Å; Y103-L105 PolarHBondContact O-N 2.91Å
106M98.3Very high98.2Very high7 Ų736.5 Ų36.53%0.03419%0.19CC..SBendtrans-63.6150.9170.9-67.2-59.1-69.200110.7F39 M101 Y103 F110 F111 W171F39-M106 HydrophobicContact CD1-CE 3.66Å; F39-M106 HydrophobicContact CE1-CE 3.8Å; F39-M106 HydrophobicContact CG-CE 4.27Å; M101-M106 HydrophobicContact CB-SD 4.41Å; Y103-M106 WeakPolarHBondContact O-CB 3.33Å; Y103-M106 WeakPolarHBondContact O-CG 3.36Å; Y103-M106 PolarHBondContact O-N 3.06Å; M106-F110 HydrophobicContact CB-CB 4.23Å; M106-F110 HydrophobicContact CB-CD1 3.59Å; M106-F110 HydrophobicContact CB-CE1 4.16Å; M106-F110 HydrophobicContact CB-CG 4.01Å; M106-F110 HydrophobicContact CE-CD1 4.49Å; M106-F110 HydrophobicContact CE-CD2 3.96Å; M106-F110 HydrophobicContact CE-CE2 4.17Å; M106-F110 HydrophobicContact CE-CG 4.14Å; M106-F110 HydrophobicContact CG-CD1 4.05Å; M106-F110 HydrophobicContact CG-CE1 4.14Å; M106-F111 HydrophobicContact CB-CZ 4.15Å; M106-F111 WeakPolarHBondContact O-CE2 3.47Å; M106-W171 HydrophobicContact CE-CH2 4.12Å; M106-W171 HydrophobicContact CG-CH2 3.6Å; M106-W171 HydrophobicContact CG-CZ2 3.7Å; M106-W171 HydrophobicContact SD-CH2 3.71Å; M106-W171 HydrophobicContact SD-CZ2 3.61Å
107P98Very high98.3Very high3 Ų336.1 Ų36.12%0.01919%0.187CC..  trans-55.3145-178.312-24.7000112.4A28 I31 V33 L79 S109 F110A28-P107 VanDerWaalsContact O-CB 3.31Å; A28-P107 WeakPolarHBondContact O-CB 3.43Å; I31-P107 HydrophobicContact CG2-CB 3.92Å; I31-P107 HydrophobicContact CG2-CG 3.83Å; V33-P107 HydrophobicContact CG2-CG 3.94Å; L79-P107 HydrophobicContact CD2-CG 4.05Å; P107-S109 PolarHBondContact O-N 3.01Å; P107-F110 HydrophobicContact CG-CB 4.04Å; P107-F110 WeakPolarHBondContact O-CB 3.4Å; P107-F110 PolarHBondContact O-N 2.96Å
108P98.4Very high98.3Very high92 Ų9236 Ų3660%0.59719%0.187SC*.THydrogen-bonded Turntrans-52.2-32.7177.4-29.837.3000114.5E29 F110 P112E29-P108 VanDerWaalsContact O-CD 3.3Å; E29-P108 WeakPolarHBondContact O-CD 3.46Å; P108-F110 VanDerWaalsContact C-N 3.3Å; P108-F110 PolarHBondContact O-N 2.86Å; P108-P112 WeakPolarHBondContact O-CD 3.29Å
109S98.4Very high98.3Very high36 Ų3636 Ų3625%0.25219%0.187SC..THydrogen-bonded Turntrans-74.3-14.8177.2670000114.5I31 V33 P107 P112I31-S109 PolarHBondContact O-OG 2.94Å; V33-S109 WeakPolarHBondContact CB-OG 3.42Å; V33-S109 WeakPolarHBondContact CG2-OG 3.45Å; V33-S109 PolarHBondContact N-OG 2.61Å; P107-S109 PolarHBondContact O-N 3.01Å; S109-P112 WeakPolarHBondContact O-CD 3.44Å
110F98.5Very high98.3Very high0 Ų036 Ų360%019%0.187CC..THydrogen-bonded Turntrans-68.6-40.7177.1166.4-97.6000112.2V33 F39 Y103 M106 P107 P108 S113 V117 W171 L176 R179V33-F110 HydrophobicContact CG2-CB 4.18Å; F39-F110 HydrophobicContact CD2-CD2 4.11Å; F39-F110 HydrophobicContact CD2-CE2 4.05Å; F39-F110 AromaticContact CE2-CD2 3.9Å; F39-F110 HydrophobicContact CE2-CD2 3.9Å; F39-F110 HydrophobicContact CE2-CE2 4.31Å; F39-F110 HydrophobicContact CG-CE2 4.48Å; F39-F110 HydrophobicContact CZ-CD2 4.28Å; Y103-F110 HydrophobicContact CD2-CE1 4.32Å; Y103-F110 AromaticContact CE2-CE1 3.89Å; Y103-F110 HydrophobicContact CE2-CE1 3.89Å; M106-F110 HydrophobicContact CB-CB 4.23Å; M106-F110 HydrophobicContact CB-CD1 3.59Å; M106-F110 HydrophobicContact CB-CE1 4.16Å; M106-F110 HydrophobicContact CB-CG 4.01Å; M106-F110 HydrophobicContact CE-CD1 4.49Å; M106-F110 HydrophobicContact CE-CD2 3.96Å; M106-F110 HydrophobicContact CE-CE2 4.17Å; M106-F110 HydrophobicContact CE-CG 4.14Å; M106-F110 HydrophobicContact CG-CD1 4.05Å; M106-F110 HydrophobicContact CG-CE1 4.14Å; P107-F110 HydrophobicContact CG-CB 4.04Å; P107-F110 WeakPolarHBondContact O-CB 3.4Å; P107-F110 PolarHBondContact O-N 2.96Å; P108-F110 VanDerWaalsContact C-N 3.3Å; P108-F110 PolarHBondContact O-N 2.86Å; F110-S113 PolarHBondContact O-N 3.23Å; F110-S113 PolarHBondContact O-OG 3.12Å; F110-V117 HydrophobicContact CE2-CG2 3.63Å; F110-V117 HydrophobicContact CZ-CG2 3.63Å; F110-W171 HydrophobicContact CZ-CH2 4.3Å; F110-W171 HydrophobicContact CZ-CZ3 4.25Å; F110-L176 HydrophobicContact CE1-CD2 4.15Å; F110-L176 HydrophobicContact CZ-CD2 3.85Å; F110-R179 PolarHBondContact O-NH2 3.46Å; F110-R179 VanDerWaalsContact O-NH2 3.17Å
111F97.9Very high98.3Very high82 Ų8235.3 Ų35.336%0.3618%0.184SC..THydrogen-bonded Turntrans-59.7-48.8-175.6-56.3-75.3000113.2Y103 M106 R179Y103-F111 HydrophobicContact CD1-CE1 4.4Å; Y103-F111 HydrophobicContact CE1-CD1 4.35Å; Y103-F111 AromaticContact CE1-CE1 3.79Å; Y103-F111 HydrophobicContact CE1-CE1 3.79Å; Y103-F111 HydrophobicContact CE2-CE1 4.29Å; Y103-F111 AromaticContact CZ-CD1 3.96Å; Y103-F111 AromaticContact CZ-CE1 3.74Å; M106-F111 HydrophobicContact CB-CZ 4.15Å; M106-F111 WeakPolarHBondContact O-CE2 3.47Å; F111-R179 PolarHBondContact O-NH1 3.14Å
112P97.6Very high98.3Very high108 Ų10835.7 Ų35.770%0.70119%0.185SC*.THydrogen-bonded Turntrans-81.5-7.9179.233.8-38.4000115.1P108 S109P108-P112 WeakPolarHBondContact O-CD 3.29Å; S109-P112 WeakPolarHBondContact O-CD 3.44Å
113S98.1Very high98.3Very high9 Ų935.7 Ų35.76%0.06318%0.184CC..SBendtrans-75.2-177.8-176.576.80000112.6V33 D35 F110 A115 R179V33-S113 WeakPolarHBondContact CG1-OG 3.31Å; D35-S113 WeakPolarHBondContact OD1-CA 3.23Å; F110-S113 PolarHBondContact O-N 3.23Å; F110-S113 PolarHBondContact O-OG 3.12Å; S113-A115 WeakPolarHBondContact OG-CB 3.42Å; S113-A115 PolarHBondContact OG-N 2.76Å; S113-R179 PolarHBondContact O-NH1 3.01Å; S113-R179 PolarHBondContact O-NH2 3.26Å; S113-R179 VanDerWaalsContact O-NH2 3.17Å; S113-R179 PolarHBondContact OG-NH2 2.91Å; S113-R179 VanDerWaalsContact OG-NH2 3.07Å
114K98.1Very high98.3Very high139 Ų13934.4 Ų34.460%0.60418%0.18SC*.  trans-107.97.5167.4-61.3176.5-171.4158.60113.8D35 K116D35-K114 HydrophobicContact CB-CB 3.94Å; D35-K114 CarbonylContact O-C 3.25Å; D35-K114 VanDerWaalsContact O-C 3.25Å; D35-K114 PolarHBondContact OD1-N 3.05Å; D35-K114 IonicContact OD2-NZ 2.94Å; K114-K116 PolarHBondContact O-N 3.28Å
115A98.5Very high98.3Very high0 Ų029.2 Ų29.20%016%0.156CC..  trans-48.6137.3-179.600000110.9V33 D35 D37 F39 S113 R179V33-A115 HydrophobicContact CG1-CB 3.67Å; D35-A115 WeakPolarHBondContact O-CA 3.47Å; D35-A115 PolarHBondContact O-N 2.76Å; D37-A115 HydrophobicContact CB-CB 4Å; D37-A115 CarbonylContact O-C 3.56Å; D37-A115 VanDerWaalsContact O-CA 3.3Å; D37-A115 WeakPolarHBondContact O-CA 3.48Å; D37-A115 WeakPolarHBondContact O-CB 3.42Å; F39-A115 HydrophobicContact CD2-CB 3.97Å; F39-A115 HydrophobicContact CE2-CB 3.7Å; S113-A115 WeakPolarHBondContact OG-CB 3.42Å; S113-A115 PolarHBondContact OG-N 2.76Å; A115-R179 PolarHBondContact O-NE 3.05Å; A115-R179 PolarHBondContact O-NH2 3.47Å; A115-R179 VanDerWaalsContact O-NH2 3.08Å
116K98.8Very high98.4Very high64 Ų6428.2 Ų28.228%0.27815%0.15SC..EExtended strand (participates in β ladder)trans-88.7148.4-179-69.6180-178.7173.80110.4D37 I38 F39 K114 R179 F202 L203D37-K116 PolarHBondContact O-N 3.22Å; I38-K116 HydrophobicContact CD1-CB 3.87Å; I38-K116 HydrophobicContact CD1-CD 4.33Å; I38-K116 HydrophobicContact CD1-CG 4.46Å; F39-K116 PolarHBondContact N-O 3.39Å; K114-K116 PolarHBondContact O-N 3.28Å; K116-R179 CarbonylContact C-O 3.48Å; K116-R179 WeakPolarHBondContact CA-O 3.48Å; K116-F202 HydrophobicContact CB-CE1 3.85Å; K116-F202 HydrophobicContact CB-CZ 3.84Å; K116-F202 HydrophobicContact CD-CE1 4.12Å; K116-F202 HydrophobicContact CD-CZ 4.15Å; K116-F202 WeakPolarHBondContact CE-O 3.45Å; K116-F202 HydrophobicContact CG-CE1 4.35Å; K116-F202 HydrophobicContact CG-CZ 4.1Å; K116-F202 PolarHBondContact NZ-O 3.45Å; K116-L203 HydrophobicContact CD-CD2 4.22Å
117V98.9Very high98.4Very high0 Ų027.9 Ų27.90%015%0.148CC..EExtended strand (participates in β ladder)trans-122.3131.2179.8-175.90000109.5F39 V41 F110 W171 R179 I180 L181 F202F39-V117 HydrophobicContact CB-CG2 4.36Å; F39-V117 CarbonylContact O-C 3.52Å; F39-V117 VanDerWaalsContact O-CA 3.3Å; F39-V117 WeakPolarHBondContact O-CA 3.44Å; V41-V117 HydrophobicContact CG2-CG1 4.18Å; F110-V117 HydrophobicContact CE2-CG2 3.63Å; F110-V117 HydrophobicContact CZ-CG2 3.63Å; V117-W171 HydrophobicContact CG1-CE3 4.24Å; V117-W171 HydrophobicContact CG1-CH2 4.47Å; V117-W171 HydrophobicContact CG1-CZ3 3.76Å; V117-W171 HydrophobicContact CG2-CZ3 4.29Å; V117-R179 PolarHBondContact N-O 3.48Å; V117-I180 HydrophobicContact CB-CB 4.22Å; V117-I180 HydrophobicContact CB-CD1 4.34Å; V117-I180 HydrophobicContact CB-CG1 4.09Å; V117-I180 HydrophobicContact CG1-CD1 4Å; V117-I180 HydrophobicContact CG1-CG1 4.12Å; V117-I180 CarbonylContact O-C 3.54Å; V117-I180 VanDerWaalsContact O-CA 3.31Å; V117-I180 WeakPolarHBondContact O-CA 3.24Å; V117-L181 PolarHBondContact O-N 2.92Å; V117-F202 WeakPolarHBondContact O-CZ 3.22Å
118I98.9Very high98.4Very high0 Ų027.7 Ų27.70%015%0.148CC..EExtended strand (participates in β ladder)trans-108.6109.3165.9-61.2157.5000106.4I38 F39 T40 V41 M51 V55 V120 L181 I183 L199 F202 L203I38-I118 HydrophobicContact CG2-CD1 4Å; F39-I118 PolarHBondContact O-N 3.4Å; T40-I118 CarbonylContact C-O 3.46Å; T40-I118 WeakPolarHBondContact CA-O 3.3Å; V41-I118 PolarHBondContact N-O 2.82Å; M51-I118 HydrophobicContact CE-CD1 4.25Å; M51-I118 HydrophobicContact CE-CG2 3.77Å; V55-I118 HydrophobicContact CG2-CD1 3.83Å; I118-V120 HydrophobicContact CG2-CG2 4.07Å; I118-L181 WeakPolarHBondContact CA-O 3.37Å; I118-I183 HydrophobicContact CG2-CD1 3.85Å; I118-L199 HydrophobicContact CD1-CD2 3.52Å; I118-L199 HydrophobicContact CG1-CD2 3.83Å; I118-L199 HydrophobicContact CG2-CD2 4.06Å; I118-F202 HydrophobicContact CG1-CD1 4.31Å; I118-F202 HydrophobicContact CG1-CE1 3.98Å; I118-L203 HydrophobicContact CD1-CD1 4.44Å; I118-L203 HydrophobicContact CD1-CD2 4.47Å
119Y98.8Very high98.4Very high0 Ų023.3 Ų23.30%012%0.119CC..EExtended strand (participates in β ladder)trans-98.5115.9178.1-170.9-103.2000110.2V41 T121 H167 V168 W171 L181 Y182 I183V41-Y119 HydrophobicContact CB-CD2 4Å; V41-Y119 HydrophobicContact CB-CE2 4.49Å; V41-Y119 HydrophobicContact CG1-CD2 4.1Å; V41-Y119 HydrophobicContact CG1-CE2 4.1Å; V41-Y119 WeakPolarHBondContact O-CA 3.2Å; V41-Y119 WeakPolarHBondContact O-CD2 3.41Å; Y119-T121 HydrophobicContact CD1-CG2 3.72Å; Y119-T121 HydrophobicContact CE1-CG2 3.15Å; Y119-H167 AromaticContact CE2-CE1 3.79Å; Y119-H167 AromaticContact CE2-ND1 3.98Å; Y119-H167 AromaticContact CZ-ND1 3.91Å; Y119-H167 PolarHBondContact OH-ND1 2.75Å; Y119-V168 WeakPolarHBondContact OH-CA 3.19Å; Y119-W171 HydrophobicContact CD1-CB 4.31Å; Y119-W171 HydrophobicContact CD2-CB 3.6Å; Y119-W171 AromaticContact CD2-CD1 3.99Å; Y119-W171 AromaticContact CD2-CD2 3.82Å; Y119-W171 HydrophobicContact CD2-CD2 3.82Å; Y119-W171 HydrophobicContact CD2-CE3 4.26Å; Y119-W171 AromaticContact CD2-CG 3.5Å; Y119-W171 HydrophobicContact CD2-CG 3.5Å; Y119-W171 VanDerWaalsContact CD2-CG 3.5Å; Y119-W171 HydrophobicContact CE1-CB 4.01Å; Y119-W171 HydrophobicContact CE2-CB 3.35Å; Y119-W171 AromaticContact CE2-CD1 3.28Å; Y119-W171 AromaticContact CE2-CD2 3.92Å; Y119-W171 HydrophobicContact CE2-CD2 3.92Å; Y119-W171 AromaticContact CE2-CG 3.18Å; Y119-W171 HydrophobicContact CE2-CG 3.18Å; Y119-W171 AromaticContact CE2-NE1 3.98Å; Y119-W171 HydrophobicContact CG-CB 4.11Å; Y119-W171 HydrophobicContact CG-CG 4.44Å; Y119-W171 AromaticContact CZ-CD1 3.95Å; Y119-W171 AromaticContact CZ-CG 3.88Å; Y119-L181 PolarHBondContact N-O 3.02Å; Y119-Y182 AromaticContact CD1-CD1 3.82Å; Y119-Y182 HydrophobicContact CD1-CD1 3.82Å; Y119-Y182 HydrophobicContact CD1-CE1 4.08Å; Y119-Y182 HydrophobicContact CG-CD1 4.28Å; Y119-Y182 HydrophobicContact CG-CE1 4.39Å; Y119-I183 PolarHBondContact O-N 3.03Å
120V98.7Very high98.4Very high0 Ų022.5 Ų22.50%011%0.113CC..EExtended strand (participates in β ladder)trans-106.6121.7179-167.50000111.3V41 T42 M51 I118 I183 M188V41-V120 PolarHBondContact O-N 3.17Å; T42-V120 HydrophobicContact CG2-CB 3.74Å; T42-V120 HydrophobicContact CG2-CG2 4.22Å; M51-V120 HydrophobicContact CG-CG2 3.67Å; M51-V120 HydrophobicContact SD-CG2 4Å; I118-V120 HydrophobicContact CG2-CG2 4.07Å; V120-I183 VanDerWaalsContact CA-O 3.3Å; V120-I183 WeakPolarHBondContact CA-O 3.41Å; V120-I183 HydrophobicContact CG2-CB 4.41Å; V120-M188 HydrophobicContact CG1-CE 3.79Å
121T98Very high98.3Very high4 Ų422.8 Ų22.83%0.02512%0.115CC..EExtended strand (participates in β ladder)trans-107.9156.5172.152.50000112Y119 V168 I183 T184 Y185 F283Y119-T121 HydrophobicContact CD1-CG2 3.72Å; Y119-T121 HydrophobicContact CE1-CG2 3.15Å; T121-V168 HydrophobicContact CG2-CG2 4.14Å; T121-I183 PolarHBondContact N-O 2.7Å; T121-T184 CarbonylContact O-C 3.51Å; T121-T184 WeakPolarHBondContact O-CA 3.35Å; T121-Y185 PolarHBondContact O-N 3.35Å; T121-F283 HydrophobicContact CG2-CE1 4.08Å
122R98.4Very high98.4Very high15 Ų1519.4 Ų19.46%0.05710%0.1CC..  trans-140.1154.5174.2-178.7174.4-170-171.66.7108.9K45 P124 D126 V127 Y185 V252 W285K45-R122 PolarHBondContact O-NH1 3.38Å; R122-P124 VanDerWaalsContact O-N 3.13Å; R122-D126 HydrophobicContact CG-CB 4.42Å; R122-V127 HydrophobicContact CB-CG2 3.75Å; R122-V127 HydrophobicContact CG-CG2 3.99Å; R122-Y185 HydrophobicContact CB-CG 4.42Å; R122-Y185 HydrophobicContact CG-CD1 4.18Å; R122-Y185 HydrophobicContact CG-CG 3.97Å; R122-V252 PolarHBondContact NH2-O 3.44Å; R122-W285 VanDerWaalsContact C-CH2 3.41Å
123N98.3Very high98.4Very high8 Ų816 Ų164%0.0438%0.075CC..  trans-48120.2173.4-174.7-38.2000110.5K125 D126 V127 E186 W285N123-K125 PolarHBondContact O-N 3.34Å; N123-K125 VanDerWaalsContact O-N 3.14Å; N123-K125 WeakPolarHBondContact OD1-CB 3.38Å; N123-K125 PolarHBondContact OD1-N 3.3Å; N123-D126 HydrophobicContact CB-CB 4.47Å; N123-D126 PolarHBondContact O-N 2.94Å; N123-V127 WeakPolarHBondContact O-CG2 3.43Å; N123-V127 PolarHBondContact O-N 3.13Å; N123-E186 WeakPolarHBondContact CB-OE1 3.3Å; N123-E186 PolarHBondContact N-OE1 3.05Å; N123-W285 HydrophobicContact CB-CB 4.43Å; N123-W285 HydrophobicContact CB-CD2 3.77Å; N123-W285 HydrophobicContact CB-CE3 4.1Å; N123-W285 HydrophobicContact CB-CG 3.92Å; N123-W285 WeakPolarHBondContact ND2-CB 3.33Å
124P98.2Very high98.3Very high3 Ų316.8 Ų16.82%0.0198%0.077CC..Hα-helixtrans-61-25.5-174.921.4-32.2000113.4R122 V127 M128 W164 F268 L272R122-P124 VanDerWaalsContact O-N 3.13Å; P124-V127 PolarHBondContact O-N 2.69Å; P124-M128 WeakPolarHBondContact O-CB 3.34Å; P124-M128 PolarHBondContact O-N 2.83Å; P124-W164 HydrophobicContact CB-CD2 3.72Å; P124-W164 HydrophobicContact CB-CE3 4.01Å; P124-W164 HydrophobicContact CB-CG 4.06Å; P124-W164 HydrophobicContact CB-CH2 4.49Å; P124-W164 HydrophobicContact CB-CZ2 4.2Å; P124-W164 HydrophobicContact CB-CZ3 4.4Å; P124-W164 HydrophobicContact CG-CD2 4.27Å; P124-W164 HydrophobicContact CG-CE3 4.19Å; P124-W164 HydrophobicContact CG-CH2 4.01Å; P124-W164 HydrophobicContact CG-CZ2 4.05Å; P124-W164 HydrophobicContact CG-CZ3 4.08Å; P124-F268 HydrophobicContact CB-CE1 4.04Å; P124-F268 HydrophobicContact CB-CZ 4.24Å; P124-F268 HydrophobicContact CG-CE1 4.26Å; P124-L272 HydrophobicContact CB-CD1 4Å; P124-L272 HydrophobicContact CG-CD1 3.3Å; P124-L272 HydrophobicContact CG-CD2 4.44Å
125K98.4Very high98.2Very high19 Ų1910.7 Ų10.78%0.0835%0.051CC..Hα-helixtrans-67.2-44.3174.4-59.2176.4-174.8174.20110.8N123 M128 V129 W256 F260 D265 F268 T269N123-K125 PolarHBondContact O-N 3.34Å; N123-K125 VanDerWaalsContact O-N 3.14Å; N123-K125 WeakPolarHBondContact OD1-CB 3.38Å; N123-K125 PolarHBondContact OD1-N 3.3Å; K125-M128 PolarHBondContact O-N 2.61Å; K125-V129 WeakPolarHBondContact O-CG2 3.47Å; K125-V129 PolarHBondContact O-N 3.06Å; K125-V129 VanDerWaalsContact O-N 3.13Å; K125-W256 HydrophobicContact CB-CB 3.6Å; K125-W256 HydrophobicContact CB-CD2 3.86Å; K125-W256 HydrophobicContact CB-CE3 4.36Å; K125-W256 HydrophobicContact CB-CG 3.51Å; K125-W256 HydrophobicContact CD-CD2 3.66Å; K125-W256 HydrophobicContact CD-CE3 3.67Å; K125-W256 HydrophobicContact CD-CG 4.27Å; K125-W256 HydrophobicContact CD-CH2 4.04Å; K125-W256 HydrophobicContact CD-CZ2 4.03Å; K125-W256 HydrophobicContact CD-CZ3 3.87Å; K125-W256 HydrophobicContact CG-CD2 4.39Å; K125-F260 HydrophobicContact CB-CE2 4.23Å; K125-F260 HydrophobicContact CB-CZ 4.08Å; K125-F260 HydrophobicContact CG-CE1 4.45Å; K125-F260 HydrophobicContact CG-CZ 4.34Å; K125-D265 WeakPolarHBondContact CE-OD1 3.26Å; K125-D265 IonicContact NZ-OD1 2.81Å; K125-D265 PolarHBondContact NZ-OD1 3.23Å; K125-F268 HydrophobicContact CB-CE1 4.37Å; K125-F268 HydrophobicContact CD-CD1 4.46Å; K125-F268 HydrophobicContact CG-CD1 3.61Å; K125-F268 HydrophobicContact CG-CE1 3.55Å; K125-F268 HydrophobicContact CG-CG 4.49Å; K125-F268 HydrophobicContact CG-CZ 4.44Å; K125-T269 VanDerWaalsContact CE-OG1 3.31Å; K125-T269 WeakPolarHBondContact CE-OG1 3.3Å; K125-T269 PolarHBondContact NZ-OG1 3.04Å
126D98.5Very high98Very high3 Ų314.9 Ų14.92%0.0167%0.069CC..Hα-helixtrans-68.2-36.2174.5-80.7-39.8000112.5R122 N123 V129 S130 G254 D255 W256R122-D126 HydrophobicContact CG-CB 4.42Å; N123-D126 HydrophobicContact CB-CB 4.47Å; N123-D126 PolarHBondContact O-N 2.94Å; D126-V129 PolarHBondContact O-N 3.35Å; D126-S130 WeakPolarHBondContact O-CB 3.5Å; D126-S130 PolarHBondContact O-N 2.95Å; D126-G254 PolarHBondContact OD2-N 3.27Å; D126-D255 PolarHBondContact OD1-N 3.16Å; D126-W256 PolarHBondContact OD1-N 2.74Å
127V98.6Very high97.9Very high0 Ų012.2 Ų12.20%06%0.058CC..Hα-helixtrans-59.4-48.3173.8169.90000110.3Y43 P44 K45 R122 N123 P124 S130 S131 F154Y43-V127 HydrophobicContact CD1-CG1 3.63Å; Y43-V127 HydrophobicContact CE1-CG1 3.65Å; P44-V127 WeakPolarHBondContact O-CG1 3.47Å; K45-V127 HydrophobicContact CB-CG1 4.48Å; R122-V127 HydrophobicContact CB-CG2 3.75Å; R122-V127 HydrophobicContact CG-CG2 3.99Å; N123-V127 WeakPolarHBondContact O-CG2 3.43Å; N123-V127 PolarHBondContact O-N 3.13Å; P124-V127 PolarHBondContact O-N 2.69Å; V127-S130 PolarHBondContact O-N 3.1Å; V127-S131 VanDerWaalsContact O-CB 3.32Å; V127-S131 WeakPolarHBondContact O-CB 3.3Å; V127-S131 PolarHBondContact O-N 3.4Å; V127-F154 HydrophobicContact CB-CZ 4.46Å; V127-F154 HydrophobicContact CG1-CE2 3.93Å; V127-F154 HydrophobicContact CG1-CZ 3.91Å
128M98.3Very high97.7Very high0 Ų012.3 Ų12.30%06%0.059CC..Hα-helixtrans-58.6-50.3177.6179.8-75.3-155.400111.1P124 K125 S130 S131 F132 F147 F150 L151 F154 F260 F268P124-M128 WeakPolarHBondContact O-CB 3.34Å; P124-M128 PolarHBondContact O-N 2.83Å; K125-M128 PolarHBondContact O-N 2.61Å; M128-S130 VanDerWaalsContact C-N 3.32Å; M128-S130 PolarHBondContact O-N 3.2Å; M128-S131 WeakPolarHBondContact O-CB 3.22Å; M128-S131 PolarHBondContact O-N 3.06Å; M128-S131 VanDerWaalsContact O-N 3.1Å; M128-F132 PolarHBondContact O-N 2.88Å; M128-F147 HydrophobicContact CE-CD1 4.07Å; M128-F147 HydrophobicContact CE-CD2 4.16Å; M128-F147 HydrophobicContact CE-CE1 3.68Å; M128-F147 HydrophobicContact CE-CE2 3.77Å; M128-F147 HydrophobicContact CE-CG 4.31Å; M128-F147 HydrophobicContact CE-CZ 3.52Å; M128-F147 HydrophobicContact SD-CE1 4.37Å; M128-F147 HydrophobicContact SD-CE2 3.71Å; M128-F147 HydrophobicContact SD-CZ 3.62Å; M128-F150 HydrophobicContact CE-CD1 4.23Å; M128-F150 HydrophobicContact CG-CD1 4.3Å; M128-F150 HydrophobicContact CG-CE1 4.4Å; M128-F150 HydrophobicContact SD-CD1 4.22Å; M128-L151 HydrophobicContact CE-CB 3.37Å; M128-L151 HydrophobicContact CE-CD1 4.09Å; M128-L151 HydrophobicContact CE-CG 3.92Å; M128-F154 HydrophobicContact CB-CD1 4.15Å; M128-F154 HydrophobicContact CB-CD2 4.02Å; M128-F154 HydrophobicContact CB-CE1 4.23Å; M128-F154 HydrophobicContact CB-CE2 4.1Å; M128-F154 HydrophobicContact CB-CG 4.04Å; M128-F154 HydrophobicContact CB-CZ 4.2Å; M128-F154 HydrophobicContact CG-CB 4.08Å; M128-F154 HydrophobicContact CG-CD1 4.27Å; M128-F154 HydrophobicContact CG-CD2 4.13Å; M128-F154 HydrophobicContact CG-CG 3.89Å; M128-F260 HydrophobicContact CE-CZ 4.41Å; M128-F260 HydrophobicContact SD-CE2 4.24Å; M128-F260 HydrophobicContact SD-CZ 4.19Å; M128-F268 HydrophobicContact CB-CE2 4.25Å; M128-F268 HydrophobicContact CB-CZ 4.29Å; M128-F268 HydrophobicContact CG-CE2 4.25Å
129V98.4Very high97.4Very high0 Ų015.9 Ų15.90%08%0.084CC..Hα-helixtrans-58.2-45.9177.2172.90000111.1K125 D126 S131 F132 H133 F147 W256 H259 F260K125-V129 WeakPolarHBondContact O-CG2 3.47Å; K125-V129 PolarHBondContact O-N 3.06Å; K125-V129 VanDerWaalsContact O-N 3.13Å; D126-V129 PolarHBondContact O-N 3.35Å; V129-S131 VanDerWaalsContact C-N 3.27Å; V129-S131 PolarHBondContact O-N 3.17Å; V129-F132 PolarHBondContact O-N 3.49Å; V129-H133 PolarHBondContact O-CD2 3.45Å; V129-H133 VanDerWaalsContact O-CD2 3.26Å; V129-H133 PolarHBondContact O-N 2.92Å; V129-F147 HydrophobicContact CG2-CE2 4.14Å; V129-F147 HydrophobicContact CG2-CZ 4.02Å; V129-W256 HydrophobicContact CG2-CB 4.16Å; V129-H259 WeakPolarHBondContact CG1-NE2 3.35Å; V129-H259 HydrophobicContact CG2-CB 4.03Å; V129-F260 HydrophobicContact CG2-CD2 4.23Å; V129-F260 HydrophobicContact CG2-CE2 3.76Å
130S98.1Very high97.2Very high19 Ų1917.1 Ų17.113%0.1339%0.089CC..Hα-helixtrans-64.3-34.2179.1-169.90000112.3D126 V127 M128 F134D126-S130 WeakPolarHBondContact O-CB 3.5Å; D126-S130 PolarHBondContact O-N 2.95Å; V127-S130 PolarHBondContact O-N 3.1Å; M128-S130 VanDerWaalsContact C-N 3.32Å; M128-S130 PolarHBondContact O-N 3.2Å; S130-F134 WeakPolarHBondContact O-CB 3.19Å; S130-F134 PolarHBondContact O-N 2.75Å
131S97.9Very high97Very high5 Ų517.6 Ų17.64%0.0359%0.092CC..Hα-helixtrans-72.3-41.5177.6-167.10000111.4V127 M128 V129 H133 F134 H135V127-S131 VanDerWaalsContact O-CB 3.32Å; V127-S131 WeakPolarHBondContact O-CB 3.3Å; V127-S131 PolarHBondContact O-N 3.4Å; M128-S131 WeakPolarHBondContact O-CB 3.22Å; M128-S131 PolarHBondContact O-N 3.06Å; M128-S131 VanDerWaalsContact O-N 3.1Å; V129-S131 VanDerWaalsContact C-N 3.27Å; V129-S131 PolarHBondContact O-N 3.17Å; S131-H133 PolarHBondContact O-N 2.96Å; S131-F134 WeakPolarHBondContact O-CB 3.36Å; S131-F134 PolarHBondContact O-N 3.04Å; S131-F134 VanDerWaalsContact O-N 3.09Å; S131-H135 PolarHBondContact O-N 3.03Å; S131-H135 PolarHBondContact O-ND1 3.35Å; S131-H135 PolarHBondContact OG-CE1 3.01Å; S131-H135 VanDerWaalsContact OG-CE1 3.3Å; S131-H135 PolarHBondContact OG-ND1 2.83Å
132F98Very high96.8Very high12 Ų1220.5 Ų20.55%0.05311%0.107CC..Hα-helixtrans-55.8-50176179-107.7000111.8M128 V129 F134 H135 K136 P144 G145 F147 F150M128-F132 PolarHBondContact O-N 2.88Å; V129-F132 PolarHBondContact O-N 3.49Å; F132-F134 VanDerWaalsContact C-N 3.31Å; F132-F134 PolarHBondContact O-N 3.36Å; F132-H135 PolarHBondContact O-N 3.4Å; F132-K136 HydrophobicContact CE1-CD 4.27Å; F132-K136 VanDerWaalsContact CZ-NZ 3.34Å; F132-K136 PolarHBondContact O-N 2.8Å; F132-P144 HydrophobicContact CD2-CB 3.59Å; F132-P144 HydrophobicContact CD2-CG 4Å; F132-P144 HydrophobicContact CE2-CB 3.79Å; F132-P144 HydrophobicContact CE2-CG 3.97Å; F132-G145 WeakPolarHBondContact CE2-O 3.37Å; F132-F147 AromaticContact CD1-CD2 3.91Å; F132-F147 HydrophobicContact CD1-CD2 3.91Å; F132-F147 HydrophobicContact CD1-CE2 4.39Å; F132-F147 HydrophobicContact CD2-CD2 4.33Å; F132-F147 AromaticContact CE1-CD2 3.95Å; F132-F147 HydrophobicContact CE1-CD2 3.95Å; F132-F147 HydrophobicContact CE2-CB 4.46Å; F132-F147 HydrophobicContact CE2-CD2 4.41Å; F132-F147 HydrophobicContact CG-CD2 4.08Å; F132-F147 HydrophobicContact CG-CE2 4.5Å; F132-F147 HydrophobicContact CZ-CB 4.23Å; F132-F147 HydrophobicContact CZ-CD2 4.21Å; F132-F150 HydrophobicContact CB-CD1 3.71Å; F132-F150 HydrophobicContact CB-CE1 3.85Å; F132-F150 HydrophobicContact CB-CG 4.41Å; F132-F150 HydrophobicContact CD2-CB 3.64Å; F132-F150 AromaticContact CD2-CD1 3.81Å; F132-F150 HydrophobicContact CD2-CD1 3.81Å; F132-F150 HydrophobicContact CD2-CD2 4.42Å; F132-F150 AromaticContact CD2-CG 3.69Å; F132-F150 HydrophobicContact CD2-CG 3.69Å; F132-F150 HydrophobicContact CE2-CB 4.06Å; F132-F150 HydrophobicContact CG-CD1 4.26Å
133H97.6Very high96.6Very high36 Ų3625.5 Ų25.517%0.16714%0.135CC..Hα-helixtrans-67.6-31.4176.9-74.3-70.4000113.2V129 S131 K136 M137 H259V129-H133 PolarHBondContact O-CD2 3.45Å; V129-H133 VanDerWaalsContact O-CD2 3.26Å; V129-H133 PolarHBondContact O-N 2.92Å; S131-H133 PolarHBondContact O-N 2.96Å; H133-K136 PolarHBondContact O-N 2.85Å; H133-M137 PolarHBondContact O-N 2.82Å; H133-H259 AromaticContact NE2-CE1 3.34Å; H133-H259 PolarHBondContact NE2-CE1 3.23Å; H133-H259 VanDerWaalsContact NE2-CE1 3.34Å; H133-H259 AromaticContact NE2-ND1 3.92Å
134F96.8Very high96.5Very high25 Ų2525.2 Ų25.211%0.1113%0.133CC..Hα-helixtrans-67.2-42.8176.1-177.8-122.4000111.9K45 S130 S131 F132 K136 M137 A138 F140 L141 L160 M240 F247K45-F134 HydrophobicContact CD-CB 4.36Å; K45-F134 HydrophobicContact CD-CD1 4Å; K45-F134 HydrophobicContact CD-CG 4.25Å; K45-F134 VanDerWaalsContact NZ-CG 3.31Å; S130-F134 WeakPolarHBondContact O-CB 3.19Å; S130-F134 PolarHBondContact O-N 2.75Å; S131-F134 WeakPolarHBondContact O-CB 3.36Å; S131-F134 PolarHBondContact O-N 3.04Å; S131-F134 VanDerWaalsContact O-N 3.09Å; F132-F134 VanDerWaalsContact C-N 3.31Å; F132-F134 PolarHBondContact O-N 3.36Å; F134-K136 VanDerWaalsContact C-N 3.26Å; F134-K136 PolarHBondContact O-N 2.78Å; F134-M137 HydrophobicContact CD2-CG 4.16Å; F134-M137 HydrophobicContact CD2-SD 4.16Å; F134-M137 WeakPolarHBondContact O-CG 3.48Å; F134-M137 PolarHBondContact O-N 3.14Å; F134-M137 VanDerWaalsContact O-N 3.1Å; F134-A138 HydrophobicContact CD2-CB 4.49Å; F134-A138 HydrophobicContact CE2-CB 4.16Å; F134-A138 HydrophobicContact CZ-CB 4.22Å; F134-A138 WeakPolarHBondContact O-CB 3.33Å; F134-A138 PolarHBondContact O-N 3.39Å; F134-F140 HydrophobicContact CZ-CE2 4.49Å; F134-F140 HydrophobicContact CZ-CZ 4.04Å; F134-L141 HydrophobicContact CD1-CD1 3.57Å; F134-L141 HydrophobicContact CE1-CD1 3.53Å; F134-L141 HydrophobicContact CG-CD1 4.47Å; F134-L141 HydrophobicContact CZ-CD1 4.37Å; F134-L160 HydrophobicContact CE1-CD1 4.48Å; F134-M240 HydrophobicContact CE2-CE 4.1Å; F134-F247 HydrophobicContact CD2-CD2 4.21Å; F134-F247 HydrophobicContact CD2-CE2 4.36Å; F134-F247 AromaticContact CE2-CD2 3.93Å; F134-F247 HydrophobicContact CE2-CD2 3.93Å; F134-F247 AromaticContact CE2-CE2 3.88Å; F134-F247 HydrophobicContact CE2-CE2 3.88Å; F134-F247 HydrophobicContact CZ-CE2 4.48Å
135H96.4Very high96.4Very high11 Ų1126.4 Ų26.45%0.05115%0.147CC..Hα-helixtrans-62.8-32.1175.3-73.768.5000112.2S131 F132 M137 D142 P144 F150S131-H135 PolarHBondContact O-N 3.03Å; S131-H135 PolarHBondContact O-ND1 3.35Å; S131-H135 PolarHBondContact OG-CE1 3.01Å; S131-H135 VanDerWaalsContact OG-CE1 3.3Å; S131-H135 PolarHBondContact OG-ND1 2.83Å; F132-H135 PolarHBondContact O-N 3.4Å; H135-M137 VanDerWaalsContact C-N 3.29Å; H135-M137 PolarHBondContact O-N 2.95Å; H135-D142 PolarHBondContact CD2-O 3.28Å; H135-P144 HydrophobicContact CB-CB 3.89Å; H135-P144 HydrophobicContact CB-CG 3.83Å; H135-F150 AromaticContact CD2-CE2 3.97Å; H135-F150 AromaticContact CE1-CE2 3.88Å; H135-F150 AromaticContact CE1-CZ 3.75Å; H135-F150 AromaticContact CG-CE2 3.89Å; H135-F150 AromaticContact ND1-CE2 3.82Å; H135-F150 AromaticContact ND1-CZ 3.67Å; H135-F150 AromaticContact NE2-CE2 3.96Å
136K94.9Very high96.4Very high88 Ų8829.2 Ų29.238%0.38317%0.165SC..Hα-helixtrans-64.7-31.9174.3-69.4-172.5174.9-174.90113.6F132 H133 F134 P144 K244F132-K136 HydrophobicContact CE1-CD 4.27Å; F132-K136 VanDerWaalsContact CZ-NZ 3.34Å; F132-K136 PolarHBondContact O-N 2.8Å; H133-K136 PolarHBondContact O-N 2.85Å; F134-K136 VanDerWaalsContact C-N 3.26Å; F134-K136 PolarHBondContact O-N 2.78Å; K136-P144 HydrophobicContact CG-CG 3.65Å; K136-K244 WeakPolarHBondContact O-CD 3.48Å
137M94.8Very high96.3Very high8 Ų830.7 Ų30.74%0.03917%0.172CC..Hα-helixtrans-97.8-27.6-174.169.2170.1-58.200114.1H133 F134 H135 M240 D241 K244 S245H133-M137 PolarHBondContact O-N 2.82Å; F134-M137 HydrophobicContact CD2-CG 4.16Å; F134-M137 HydrophobicContact CD2-SD 4.16Å; F134-M137 WeakPolarHBondContact O-CG 3.48Å; F134-M137 PolarHBondContact O-N 3.14Å; F134-M137 VanDerWaalsContact O-N 3.1Å; H135-M137 VanDerWaalsContact C-N 3.29Å; H135-M137 PolarHBondContact O-N 2.95Å; M137-M240 HydrophobicContact CE-CB 3.99Å; M137-M240 HydrophobicContact CE-CE 3.69Å; M137-M240 HydrophobicContact CE-CG 4.5Å; M137-M240 HydrophobicContact SD-CE 4.41Å; M137-D241 PolarHBondContact O-N 3.27Å; M137-K244 HydrophobicContact CB-CB 4.43Å; M137-S245 WeakPolarHBondContact CE-O 3.46Å
138A95.1Very high96.3Very high3 Ų333.8 Ų33.83%0.02519%0.188CC..BIsolated β-bridgetrans-89.8113.8-176.900000110.6F134 F140 L141 I239F134-A138 HydrophobicContact CD2-CB 4.49Å; F134-A138 HydrophobicContact CE2-CB 4.16Å; F134-A138 HydrophobicContact CZ-CB 4.22Å; F134-A138 WeakPolarHBondContact O-CB 3.33Å; F134-A138 PolarHBondContact O-N 3.39Å; A138-F140 HydrophobicContact CB-CD1 4.14Å; A138-F140 HydrophobicContact CB-CE1 3.7Å; A138-F140 HydrophobicContact CB-CE2 4.14Å; A138-F140 HydrophobicContact CB-CZ 3.71Å; A138-F140 PolarHBondContact O-N 3.17Å; A138-L141 HydrophobicContact CB-CB 4.38Å; A138-L141 HydrophobicContact CB-CD1 3.85Å; A138-L141 HydrophobicContact CB-CG 3.89Å; A138-L141 PolarHBondContact O-N 3.45Å; A138-I239 WeakPolarHBondContact CA-O 3.49Å
139S93.9Very high96.3Very high75 Ų7538.6 Ų38.652%0.52421%0.211SC..THydrogen-bonded Turntrans-69.7-19.4-175.560.20000114L141 E238 I239S139-L141 VanDerWaalsContact C-N 3.27Å; S139-E238 VanDerWaalsContact CB-O 3.25Å; S139-E238 WeakPolarHBondContact CB-O 3.25Å; S139-E238 PolarHBondContact OG-O 2.89Å; S139-I239 PolarHBondContact N-O 3.39Å; S139-I239 WeakPolarHBondContact OG-CA 3.26Å; S139-I239 PolarHBondContact OG-O 3.41Å
140F93.6Very high96.2Very high26 Ų2638.7 Ų38.711%0.11421%0.211CC..THydrogen-bonded Turntrans-85.95.5176.259.7-95.5000113.7N6 P16 E18 F134 A138 I239 M240N6-F140 WeakPolarHBondContact CB-O 3.45Å; P16-F140 HydrophobicContact CB-CD2 3.84Å; P16-F140 HydrophobicContact CB-CE2 4.2Å; P16-F140 HydrophobicContact CG-CD2 4.38Å; P16-F140 HydrophobicContact CG-CE2 4.34Å; E18-F140 HydrophobicContact CB-CB 3.47Å; E18-F140 VanDerWaalsContact CB-CB 3.47Å; E18-F140 HydrophobicContact CB-CD1 4.22Å; E18-F140 HydrophobicContact CB-CD2 4.13Å; E18-F140 HydrophobicContact CB-CG 3.69Å; E18-F140 HydrophobicContact CG-CB 3.95Å; E18-F140 HydrophobicContact CG-CD1 3.95Å; E18-F140 HydrophobicContact CG-CG 3.95Å; F134-F140 HydrophobicContact CZ-CE2 4.49Å; F134-F140 HydrophobicContact CZ-CZ 4.04Å; A138-F140 HydrophobicContact CB-CD1 4.14Å; A138-F140 HydrophobicContact CB-CE1 3.7Å; A138-F140 HydrophobicContact CB-CE2 4.14Å; A138-F140 HydrophobicContact CB-CZ 3.71Å; A138-F140 PolarHBondContact O-N 3.17Å; F140-I239 HydrophobicContact CD1-CG2 3.69Å; F140-I239 HydrophobicContact CE1-CG2 3.71Å; F140-M240 HydrophobicContact CE1-CG 4.24Å
141L95.1Very high96.3Very high9 Ų937.8 Ų37.85%0.04721%0.205CC..SBendtrans-113.3153173.2-59.3-176.2000109.8Y7 P16 F134 A138 S139 L160Y7-L141 HydrophobicContact CE1-CD2 3.81Å; P16-L141 HydrophobicContact CB-CD2 4.33Å; P16-L141 HydrophobicContact CG-CD2 3.89Å; F134-L141 HydrophobicContact CD1-CD1 3.57Å; F134-L141 HydrophobicContact CE1-CD1 3.53Å; F134-L141 HydrophobicContact CG-CD1 4.47Å; F134-L141 HydrophobicContact CZ-CD1 4.37Å; A138-L141 HydrophobicContact CB-CB 4.38Å; A138-L141 HydrophobicContact CB-CD1 3.85Å; A138-L141 HydrophobicContact CB-CG 3.89Å; A138-L141 PolarHBondContact O-N 3.45Å; S139-L141 VanDerWaalsContact C-N 3.27Å; L141-L160 HydrophobicContact CD1-CD1 3.98Å; L141-L160 HydrophobicContact CD2-CD1 3.88Å; L141-L160 HydrophobicContact CD2-CD2 3.82Å; L141-L160 HydrophobicContact CD2-CG 4.26Å
142D93.8Very high96.3Very high65 Ų6540.2 Ų40.235%0.34822%0.218SC..  trans-65.6148.6174.3-70.3-2.9000111.2N6 Y7 H135N6-D142 PolarHBondContact ND2-OD1 2.9Å; Y7-D142 HydrophobicContact CE2-CB 4.3Å; Y7-D142 WeakPolarHBondContact CE2-OD2 3.28Å; Y7-D142 PolarHBondContact OH-N 2.87Å; H135-D142 PolarHBondContact CD2-O 3.28Å
143D93.9Very high96.3Very high121 Ų12143 Ų4365%0.64723%0.23SC*.  trans-55.1124.8171.7-173.7-14000109.3G145D143-G145 PolarHBondContact O-N 3Å; D143-G145 PolarHBondContact OD1-N 3.27Å
144P95.3Very high96.3Very high1 Ų141.5 Ų41.51%0.00622%0.223CC..  trans-66.6-18.6-179.726.7-33.4000112.4F132 H135 K136 F150F132-P144 HydrophobicContact CD2-CB 3.59Å; F132-P144 HydrophobicContact CD2-CG 4Å; F132-P144 HydrophobicContact CE2-CB 3.79Å; F132-P144 HydrophobicContact CE2-CG 3.97Å; H135-P144 HydrophobicContact CB-CB 3.89Å; H135-P144 HydrophobicContact CB-CG 3.83Å; K136-P144 HydrophobicContact CG-CG 3.65Å; P144-F150 HydrophobicContact CB-CB 4.23Å; P144-F150 HydrophobicContact CB-CD2 3.39Å; P144-F150 HydrophobicContact CB-CE2 3.92Å; P144-F150 HydrophobicContact CB-CG 3.93Å
145G96.5Very high96.4Very high29 Ų2941.1 Ų41.130%0.29922%0.222SC..  trans72.5-145.6-173.500000111.7F132 D143F132-G145 WeakPolarHBondContact CE2-O 3.37Å; D143-G145 PolarHBondContact O-N 3Å; D143-G145 PolarHBondContact OD1-N 3.27Å
146T97.8Very high96.4Very high78 Ų7843.2 Ų43.248%0.47924%0.237SC..SBendtrans-71.1160.5172.766.20000111.4D148 E149 F150T146-D148 VanDerWaalsContact C-N 3.26Å; T146-D148 PolarHBondContact O-N 3.13Å; T146-E149 WeakPolarHBondContact CB-OE2 3.49Å; T146-E149 WeakPolarHBondContact CG2-OE2 3.27Å; T146-E149 PolarHBondContact N-OE2 2.74Å; T146-E149 PolarHBondContact O-N 2.62Å; T146-E149 WeakPolarHBondContact OG1-CB 3.17Å; T146-E149 WeakPolarHBondContact OG1-CG 3.48Å; T146-E149 PolarHBondContact OG1-N 2.86Å; T146-E149 PolarHBondContact OG1-OE2 3.49Å; T146-F150 PolarHBondContact O-N 3.07Å
147F97.6Very high96.6Very high33 Ų3339.7 Ų39.715%0.14523%0.226CC..Hα-helixtrans-60.7-37178-168-99.1000112.1M128 V129 F132 L151 H259 F260M128-F147 HydrophobicContact CE-CD1 4.07Å; M128-F147 HydrophobicContact CE-CD2 4.16Å; M128-F147 HydrophobicContact CE-CE1 3.68Å; M128-F147 HydrophobicContact CE-CE2 3.77Å; M128-F147 HydrophobicContact CE-CG 4.31Å; M128-F147 HydrophobicContact CE-CZ 3.52Å; M128-F147 HydrophobicContact SD-CE1 4.37Å; M128-F147 HydrophobicContact SD-CE2 3.71Å; M128-F147 HydrophobicContact SD-CZ 3.62Å; V129-F147 HydrophobicContact CG2-CE2 4.14Å; V129-F147 HydrophobicContact CG2-CZ 4.02Å; F132-F147 AromaticContact CD1-CD2 3.91Å; F132-F147 HydrophobicContact CD1-CD2 3.91Å; F132-F147 HydrophobicContact CD1-CE2 4.39Å; F132-F147 HydrophobicContact CD2-CD2 4.33Å; F132-F147 AromaticContact CE1-CD2 3.95Å; F132-F147 HydrophobicContact CE1-CD2 3.95Å; F132-F147 HydrophobicContact CE2-CB 4.46Å; F132-F147 HydrophobicContact CE2-CD2 4.41Å; F132-F147 HydrophobicContact CG-CD2 4.08Å; F132-F147 HydrophobicContact CG-CE2 4.5Å; F132-F147 HydrophobicContact CZ-CB 4.23Å; F132-F147 HydrophobicContact CZ-CD2 4.21Å; F147-L151 VanDerWaalsContact O-CB 3.31Å; F147-L151 WeakPolarHBondContact O-CB 3.49Å; F147-L151 PolarHBondContact O-N 2.96Å; F147-H259 HydrophobicContact CE1-CB 4.41Å; F147-H259 HydrophobicContact CE2-CB 3.93Å; F147-H259 HydrophobicContact CZ-CB 3.72Å; F147-F260 AromaticContact CE1-CD2 3.94Å; F147-F260 HydrophobicContact CE1-CD2 3.94Å; F147-F260 HydrophobicContact CE1-CE2 4.03Å; F147-F260 HydrophobicContact CE1-CG 4.3Å; F147-F260 HydrophobicContact CE1-CZ 4.46Å; F147-F260 AromaticContact CZ-CD2 3.72Å; F147-F260 HydrophobicContact CZ-CD2 3.72Å; F147-F260 AromaticContact CZ-CE2 3.6Å; F147-F260 HydrophobicContact CZ-CE2 3.6Å; F147-F260 HydrophobicContact CZ-CZ 4.3Å
148D97.9Very high96.6Very high66 Ų6645.2 Ų45.235%0.35325%0.252SS..Hα-helixtrans-69.9-43178.7-163.479000112.5T146 F150 L151 N152 Q264T146-D148 VanDerWaalsContact C-N 3.26Å; T146-D148 PolarHBondContact O-N 3.13Å; D148-F150 VanDerWaalsContact C-N 3.33Å; D148-F150 PolarHBondContact O-N 2.8Å; D148-L151 WeakPolarHBondContact O-CB 3.43Å; D148-L151 PolarHBondContact O-N 3.45Å; D148-N152 VanDerWaalsContact O-CG 3.23Å; D148-N152 PolarHBondContact O-N 3.3Å; D148-N152 PolarHBondContact O-ND2 2.82Å; D148-N152 PolarHBondContact OD2-ND2 2.75Å; D148-Q264 PolarHBondContact OD1-NE2 2.94Å
149E98Very high96.7Very high101 Ų10145.2 Ų45.247%0.47225%0.252SS..Hα-helixtrans-59.4-46174.2-72.9163.4151.400111.1T146 L151 N152 K153T146-E149 WeakPolarHBondContact CB-OE2 3.49Å; T146-E149 WeakPolarHBondContact CG2-OE2 3.27Å; T146-E149 PolarHBondContact N-OE2 2.74Å; T146-E149 PolarHBondContact O-N 2.62Å; T146-E149 WeakPolarHBondContact OG1-CB 3.17Å; T146-E149 WeakPolarHBondContact OG1-CG 3.48Å; T146-E149 PolarHBondContact OG1-N 2.86Å; T146-E149 PolarHBondContact OG1-OE2 3.49Å; E149-L151 VanDerWaalsContact C-N 3.34Å; E149-L151 PolarHBondContact O-N 3.41Å; E149-N152 PolarHBondContact O-N 3.27Å; E149-K153 WeakPolarHBondContact O-CG 3.12Å; E149-K153 PolarHBondContact O-N 3.37Å
150F98.3Very high96.8Very high2 Ų242.1 Ų42.11%0.00923%0.229CC..Hα-helixtrans-65.9-36.7177.5-166.4-102.2000112.6M128 F132 H135 P144 T146 D148 N152 K153 F154 V159M128-F150 HydrophobicContact CE-CD1 4.23Å; M128-F150 HydrophobicContact CG-CD1 4.3Å; M128-F150 HydrophobicContact CG-CE1 4.4Å; M128-F150 HydrophobicContact SD-CD1 4.22Å; F132-F150 HydrophobicContact CB-CD1 3.71Å; F132-F150 HydrophobicContact CB-CE1 3.85Å; F132-F150 HydrophobicContact CB-CG 4.41Å; F132-F150 HydrophobicContact CD2-CB 3.64Å; F132-F150 AromaticContact CD2-CD1 3.81Å; F132-F150 HydrophobicContact CD2-CD1 3.81Å; F132-F150 HydrophobicContact CD2-CD2 4.42Å; F132-F150 AromaticContact CD2-CG 3.69Å; F132-F150 HydrophobicContact CD2-CG 3.69Å; F132-F150 HydrophobicContact CE2-CB 4.06Å; F132-F150 HydrophobicContact CG-CD1 4.26Å; H135-F150 AromaticContact CD2-CE2 3.97Å; H135-F150 AromaticContact CE1-CE2 3.88Å; H135-F150 AromaticContact CE1-CZ 3.75Å; H135-F150 AromaticContact CG-CE2 3.89Å; H135-F150 AromaticContact ND1-CE2 3.82Å; H135-F150 AromaticContact ND1-CZ 3.67Å; H135-F150 AromaticContact NE2-CE2 3.96Å; P144-F150 HydrophobicContact CB-CB 4.23Å; P144-F150 HydrophobicContact CB-CD2 3.39Å; P144-F150 HydrophobicContact CB-CE2 3.92Å; P144-F150 HydrophobicContact CB-CG 3.93Å; T146-F150 PolarHBondContact O-N 3.07Å; D148-F150 VanDerWaalsContact C-N 3.33Å; D148-F150 PolarHBondContact O-N 2.8Å; F150-N152 VanDerWaalsContact C-N 3.29Å; F150-N152 PolarHBondContact O-N 3.1Å; F150-K153 PolarHBondContact O-N 2.95Å; F150-F154 WeakPolarHBondContact O-CB 3.34Å; F150-F154 PolarHBondContact O-N 2.89Å; F150-V159 HydrophobicContact CE2-CG1 4.15Å; F150-V159 HydrophobicContact CZ-CG1 4.2Å
151L98.5Very high97.1Very high0 Ų041.3 Ų41.30%023%0.225CC..Hα-helixtrans-57-46.1173.4-172.8150.5000110.7M128 F147 D148 E149 F154 L155 F260 Q264 K267 F268M128-L151 HydrophobicContact CE-CB 3.37Å; M128-L151 HydrophobicContact CE-CD1 4.09Å; M128-L151 HydrophobicContact CE-CG 3.92Å; F147-L151 VanDerWaalsContact O-CB 3.31Å; F147-L151 WeakPolarHBondContact O-CB 3.49Å; F147-L151 PolarHBondContact O-N 2.96Å; D148-L151 WeakPolarHBondContact O-CB 3.43Å; D148-L151 PolarHBondContact O-N 3.45Å; E149-L151 VanDerWaalsContact C-N 3.34Å; E149-L151 PolarHBondContact O-N 3.41Å; L151-F154 PolarHBondContact O-N 3.49Å; L151-L155 HydrophobicContact CD2-CD1 3.55Å; L151-L155 HydrophobicContact CD2-CG 4.3Å; L151-L155 WeakPolarHBondContact O-CG 3.24Å; L151-L155 PolarHBondContact O-N 3.06Å; L151-F260 HydrophobicContact CD1-CD1 4.33Å; L151-F260 HydrophobicContact CD1-CE1 3.81Å; L151-F260 HydrophobicContact CD1-CZ 4.38Å; L151-Q264 HydrophobicContact CD1-CB 3.79Å; L151-Q264 HydrophobicContact CD1-CG 4.07Å; L151-K267 HydrophobicContact CD2-CD 4.24Å; L151-F268 HydrophobicContact CD1-CD2 4.26Å; L151-F268 HydrophobicContact CD2-CD2 4.38Å; L151-F268 HydrophobicContact CG-CD2 4.01Å
152N98.1Very high97.2Very high56 Ų5641.2 Ų41.230%0.29923%0.226SC..Hα-helixtrans-67-40.9179.1-63.9-37000112.1D148 E149 F150 F154 S156 K267D148-N152 VanDerWaalsContact O-CG 3.23Å; D148-N152 PolarHBondContact O-N 3.3Å; D148-N152 PolarHBondContact O-ND2 2.82Å; D148-N152 PolarHBondContact OD2-ND2 2.75Å; E149-N152 PolarHBondContact O-N 3.27Å; F150-N152 VanDerWaalsContact C-N 3.29Å; F150-N152 PolarHBondContact O-N 3.1Å; N152-F154 VanDerWaalsContact C-N 3.35Å; N152-S156 WeakPolarHBondContact O-CB 3.37Å; N152-S156 PolarHBondContact O-N 3.22Å; N152-S156 PolarHBondContact O-OG 2.86Å; N152-K267 WeakPolarHBondContact OD1-CE 3.5Å; N152-K267 PolarHBondContact OD1-NZ 2.8Å
153K98Very high97.4Very high70 Ų7041.1 Ų41.130%0.30422%0.223SC..Hα-helixtrans-60.1-44.6172.7-72.2177.2179.6178.30111.5E149 F150 S156 G157 Q158 V159E149-K153 WeakPolarHBondContact O-CG 3.12Å; E149-K153 PolarHBondContact O-N 3.37Å; F150-K153 PolarHBondContact O-N 2.95Å; K153-S156 WeakPolarHBondContact CA-OG 3.45Å; K153-S156 PolarHBondContact O-N 3.27Å; K153-S156 PolarHBondContact O-OG 2.98Å; K153-S156 VanDerWaalsContact O-OG 3.05Å; K153-G157 PolarHBondContact O-N 3.47Å; K153-G157 VanDerWaalsContact O-N 3.08Å; K153-Q158 HydrophobicContact CB-CB 4.34Å; K153-Q158 PolarHBondContact O-N 3.15Å; K153-V159 HydrophobicContact CB-CG1 4.08Å
154F98.5Very high97.6Very high5 Ų535.8 Ų35.82%0.02219%0.194CC..Hα-helixtrans-62.1-49.9179.4-172.5-86000112Y43 V127 M128 F150 L151 N152 S156 G157 V159 W164 F268Y43-F154 AromaticContact CE1-CE2 3.96Å; Y43-F154 HydrophobicContact CE1-CE2 3.96Å; Y43-F154 HydrophobicContact CE1-CZ 4.17Å; V127-F154 HydrophobicContact CB-CZ 4.46Å; V127-F154 HydrophobicContact CG1-CE2 3.93Å; V127-F154 HydrophobicContact CG1-CZ 3.91Å; M128-F154 HydrophobicContact CB-CD1 4.15Å; M128-F154 HydrophobicContact CB-CD2 4.02Å; M128-F154 HydrophobicContact CB-CE1 4.23Å; M128-F154 HydrophobicContact CB-CE2 4.1Å; M128-F154 HydrophobicContact CB-CG 4.04Å; M128-F154 HydrophobicContact CB-CZ 4.2Å; M128-F154 HydrophobicContact CG-CB 4.08Å; M128-F154 HydrophobicContact CG-CD1 4.27Å; M128-F154 HydrophobicContact CG-CD2 4.13Å; M128-F154 HydrophobicContact CG-CG 3.89Å; F150-F154 WeakPolarHBondContact O-CB 3.34Å; F150-F154 PolarHBondContact O-N 2.89Å; L151-F154 PolarHBondContact O-N 3.49Å; N152-F154 VanDerWaalsContact C-N 3.35Å; F154-S156 VanDerWaalsContact C-N 3.29Å; F154-S156 PolarHBondContact O-N 2.85Å; F154-G157 PolarHBondContact O-N 3.4Å; F154-G157 VanDerWaalsContact O-N 3.14Å; F154-V159 HydrophobicContact CB-CG1 4.45Å; F154-V159 HydrophobicContact CD2-CG2 4.16Å; F154-W164 HydrophobicContact CE1-CB 4.22Å; F154-W164 HydrophobicContact CZ-CB 4.02Å; F154-F268 AromaticContact CD1-CE2 3.75Å; F154-F268 HydrophobicContact CD1-CE2 3.75Å; F154-F268 AromaticContact CD1-CZ 3.84Å; F154-F268 HydrophobicContact CD1-CZ 3.84Å; F154-F268 HydrophobicContact CE1-CE2 4.13Å; F154-F268 AromaticContact CE1-CZ 3.72Å; F154-F268 HydrophobicContact CE1-CZ 3.72Å
155L98.3Very high97.8Very high17 Ų1735.8 Ų35.89%0.08919%0.194CC..Hα-helixtrans-64.7-32.2179.2-70.5177.8000112.9L151 G157 K163 F268 V271L151-L155 HydrophobicContact CD2-CD1 3.55Å; L151-L155 HydrophobicContact CD2-CG 4.3Å; L151-L155 WeakPolarHBondContact O-CG 3.24Å; L151-L155 PolarHBondContact O-N 3.06Å; L155-G157 VanDerWaalsContact C-N 3.31Å; L155-K163 WeakPolarHBondContact O-CE 3.49Å; L155-F268 HydrophobicContact CD1-CD2 4.06Å; L155-F268 HydrophobicContact CD2-CD2 3.59Å; L155-F268 HydrophobicContact CD2-CE2 3.68Å; L155-F268 HydrophobicContact CD2-CG 4.04Å; L155-F268 HydrophobicContact CD2-CZ 4.22Å; L155-F268 HydrophobicContact CG-CD2 3.88Å; L155-F268 HydrophobicContact CG-CE2 4.09Å; L155-V271 HydrophobicContact CB-CG1 4.41Å; L155-V271 HydrophobicContact CD1-CB 4.31Å; L155-V271 HydrophobicContact CD1-CG2 4.17Å; L155-V271 HydrophobicContact CD2-CB 4.14Å; L155-V271 HydrophobicContact CD2-CG1 3.94Å
156S97.5Very high97.8Very high54 Ų5438.2 Ų38.238%0.37820%0.2SC..Hα-helixtrans-82-7.8176.658.40000113.9N152 K153 F154 Q158 K163N152-S156 WeakPolarHBondContact O-CB 3.37Å; N152-S156 PolarHBondContact O-N 3.22Å; N152-S156 PolarHBondContact O-OG 2.86Å; K153-S156 WeakPolarHBondContact CA-OG 3.45Å; K153-S156 PolarHBondContact O-N 3.27Å; K153-S156 PolarHBondContact O-OG 2.98Å; K153-S156 VanDerWaalsContact O-OG 3.05Å; F154-S156 VanDerWaalsContact C-N 3.29Å; F154-S156 PolarHBondContact O-N 2.85Å; S156-Q158 VanDerWaalsContact C-N 3.32Å; S156-K163 WeakPolarHBondContact O-CE 3.4Å
157G97.3Very high97.9Very high14 Ų1434.6 Ų34.614%0.14418%0.178CC..THydrogen-bonded Turntrans77.514.5-177.100000114.3K153 F154 L155 V159 G162K153-G157 PolarHBondContact O-N 3.47Å; K153-G157 VanDerWaalsContact O-N 3.08Å; F154-G157 PolarHBondContact O-N 3.4Å; F154-G157 VanDerWaalsContact O-N 3.14Å; L155-G157 VanDerWaalsContact C-N 3.31Å; G157-V159 PolarHBondContact O-N 2.66Å; G157-G162 WeakPolarHBondContact O-CA 3.4Å
158Q96.4Very high97.9Very high125 Ų12533 Ų3358%0.58417%0.171SC*.  trans-83.347.4175.8-62.1177.613.900111K153 S156K153-Q158 HydrophobicContact CB-CB 4.34Å; K153-Q158 PolarHBondContact O-N 3.15Å; S156-Q158 VanDerWaalsContact C-N 3.32Å
159V96.8Very high97.9Very high3 Ų333.2 Ų33.22%0.01817%0.169CC..SBendtrans-140.8174.8-179.3-66.90000109.3Y43 F150 K153 F154 G157 F161 G162Y43-V159 WeakPolarHBondContact OH-CG2 3.43Å; F150-V159 HydrophobicContact CE2-CG1 4.15Å; F150-V159 HydrophobicContact CZ-CG1 4.2Å; K153-V159 HydrophobicContact CB-CG1 4.08Å; F154-V159 HydrophobicContact CB-CG1 4.45Å; F154-V159 HydrophobicContact CD2-CG2 4.16Å; G157-V159 PolarHBondContact O-N 2.66Å; V159-F161 PolarHBondContact O-N 3.46Å; V159-G162 PolarHBondContact O-N 3.14Å; V159-G162 VanDerWaalsContact O-N 3.14Å
160L96.7Very high97.9Very high9 Ų929.6 Ų29.65%0.04715%0.154CC..BIsolated β-bridgetrans-48.3126.5176.5-60.6-177.7000112Y7 L14 P16 Y43 P44 F134 L141 G162Y7-L160 HydrophobicContact CD1-CD2 4.01Å; Y7-L160 HydrophobicContact CE1-CD2 3.5Å; L14-L160 WeakPolarHBondContact O-CA 3.34Å; P16-L160 HydrophobicContact CG-CD2 3.71Å; Y43-L160 PolarHBondContact OH-O 3.32Å; P44-L160 HydrophobicContact CG-CB 4.49Å; F134-L160 HydrophobicContact CE1-CD1 4.48Å; L141-L160 HydrophobicContact CD1-CD1 3.98Å; L141-L160 HydrophobicContact CD2-CD1 3.88Å; L141-L160 HydrophobicContact CD2-CD2 3.82Å; L141-L160 HydrophobicContact CD2-CG 4.26Å; L160-G162 PolarHBondContact O-N 3.08Å
161F97.9Very high97.9Very high9 Ų929.5 Ų29.54%0.03915%0.154CC..THydrogen-bonded Turntrans59.723.1177.1-59.5-90.6000115.8L14 H20 P44 E80 H100 M101 V159L14-F161 PolarHBondContact O-N 2.84Å; L14-F161 VanDerWaalsContact O-N 3.12Å; H20-F161 AromaticContact NE2-CZ 3.7Å; P44-F161 HydrophobicContact CG-CB 4.03Å; P44-F161 HydrophobicContact CG-CD2 3.4Å; P44-F161 VanDerWaalsContact CG-CD2 3.4Å; P44-F161 HydrophobicContact CG-CE2 4.18Å; P44-F161 HydrophobicContact CG-CG 4.01Å; E80-F161 HydrophobicContact CG-CE1 4.41Å; E80-F161 HydrophobicContact CG-CZ 4.4Å; H100-F161 HydrophobicContact CB-CD1 3.64Å; H100-F161 HydrophobicContact CB-CD2 3.84Å; H100-F161 HydrophobicContact CB-CE1 3.55Å; H100-F161 HydrophobicContact CB-CE2 3.75Å; H100-F161 HydrophobicContact CB-CG 3.78Å; H100-F161 HydrophobicContact CB-CZ 3.6Å; H100-F161 VanDerWaalsContact O-CD1 3.23Å; H100-F161 WeakPolarHBondContact O-CD1 3.44Å; M101-F161 HydrophobicContact CE-CE1 4.2Å; M101-F161 HydrophobicContact SD-CE1 4.27Å; V159-F161 PolarHBondContact O-N 3.46Å
162G97.9Very high97.7Very high7 Ų733.6 Ų33.67%0.07217%0.169CC..SBendtrans78.6-15016600000114.3Y43 G157 V159 L160Y43-G162 PolarHBondContact OH-O 3.05Å; G157-G162 WeakPolarHBondContact O-CA 3.4Å; V159-G162 PolarHBondContact O-N 3.14Å; V159-G162 VanDerWaalsContact O-N 3.14Å; L160-G162 PolarHBondContact O-N 3.08Å
163K98.3Very high97.4Very high63 Ų6332.7 Ų32.727%0.27416%0.164SC..  trans-78.5133.6-179.3-69.6-171.5174.7-169.10111.6L155 S156 T165 D166 H167 E275L155-K163 WeakPolarHBondContact O-CE 3.49Å; S156-K163 WeakPolarHBondContact O-CE 3.4Å; K163-T165 VanDerWaalsContact C-N 3.29Å; K163-T165 PolarHBondContact O-N 2.79Å; K163-D166 HydrophobicContact CB-CB 4.11Å; K163-D166 PolarHBondContact O-N 3.38Å; K163-H167 PolarHBondContact O-N 3.38Å; K163-E275 IonicContact NZ-OE1 2.65Å; K163-E275 PolarHBondContact NZ-OE1 3.04Å
164W98.6Very high97.1Very high9 Ų934.3 Ų34.33%0.03419%0.185CC..Hα-helixtrans-56.6-42.4173178.394.8000112.5Y43 P124 F154 H167 V168 L272 M276 F283 W285Y43-W164 AromaticContact CD1-CD1 3.67Å; Y43-W164 HydrophobicContact CD1-CG 4.5Å; Y43-W164 HydrophobicContact CD2-CB 4.38Å; Y43-W164 HydrophobicContact CE1-CB 4.34Å; Y43-W164 HydrophobicContact CE2-CB 4.19Å; Y43-W164 AromaticContact CG-CD1 3.74Å; Y43-W164 HydrophobicContact CG-CG 4.46Å; P124-W164 HydrophobicContact CB-CD2 3.72Å; P124-W164 HydrophobicContact CB-CE3 4.01Å; P124-W164 HydrophobicContact CB-CG 4.06Å; P124-W164 HydrophobicContact CB-CH2 4.49Å; P124-W164 HydrophobicContact CB-CZ2 4.2Å; P124-W164 HydrophobicContact CB-CZ3 4.4Å; P124-W164 HydrophobicContact CG-CD2 4.27Å; P124-W164 HydrophobicContact CG-CE3 4.19Å; P124-W164 HydrophobicContact CG-CH2 4.01Å; P124-W164 HydrophobicContact CG-CZ2 4.05Å; P124-W164 HydrophobicContact CG-CZ3 4.08Å; F154-W164 HydrophobicContact CE1-CB 4.22Å; F154-W164 HydrophobicContact CZ-CB 4.02Å; W164-H167 PolarHBondContact O-N 3.4Å; W164-V168 HydrophobicContact CD2-CG2 3.89Å; W164-V168 HydrophobicContact CE3-CG2 4.22Å; W164-V168 HydrophobicContact CH2-CG1 4.42Å; W164-V168 HydrophobicContact CH2-CG2 3.99Å; W164-V168 HydrophobicContact CZ2-CG2 3.66Å; W164-V168 HydrophobicContact CZ3-CG2 4.25Å; W164-V168 WeakPolarHBondContact O-CB 3.32Å; W164-V168 WeakPolarHBondContact O-CG2 3.03Å; W164-V168 PolarHBondContact O-N 3.37Å; W164-L272 HydrophobicContact CE3-CD2 4.13Å; W164-L272 HydrophobicContact CZ3-CD2 4.38Å; W164-M276 HydrophobicContact CZ3-SD 4.37Å; W164-F283 HydrophobicContact CH2-CD2 4.39Å; W164-F283 AromaticContact CH2-CE2 3.68Å; W164-F283 HydrophobicContact CH2-CE2 3.68Å; W164-F283 AromaticContact CH2-CZ 3.88Å; W164-F283 HydrophobicContact CH2-CZ 3.88Å; W164-F283 HydrophobicContact CZ2-CE2 4.5Å; W164-F283 HydrophobicContact CZ2-CZ 4.34Å; W164-W285 HydrophobicContact CH2-CZ2 4.22Å; W164-W285 AromaticContact CZ2-CZ2 3.99Å; W164-W285 HydrophobicContact CZ2-CZ2 3.99Å
165T98.1Very high96.9Very high1 Ų140 Ų401%0.00622%0.215CC..Hα-helixtrans-64.2-45.1-178.949.20000111.4K163 V168 K169 L272 E275 M276K163-T165 VanDerWaalsContact C-N 3.29Å; K163-T165 PolarHBondContact O-N 2.79Å; T165-V168 PolarHBondContact O-N 3Å; T165-K169 VanDerWaalsContact C-CE 3.44Å; T165-K169 WeakPolarHBondContact O-CB 3.32Å; T165-K169 WeakPolarHBondContact O-CE 3.29Å; T165-K169 VanDerWaalsContact O-CG 3.26Å; T165-K169 WeakPolarHBondContact O-CG 3.43Å; T165-K169 PolarHBondContact O-N 3.34Å; T165-L272 HydrophobicContact CG2-CD2 3.39Å; T165-E275 WeakPolarHBondContact CB-OE2 3.33Å; T165-E275 HydrophobicContact CG2-CB 3.88Å; T165-E275 WeakPolarHBondContact CG2-OE2 3.04Å; T165-E275 PolarHBondContact OG1-OE2 3.34Å; T165-M276 HydrophobicContact CG2-CG 3.88Å; T165-M276 HydrophobicContact CG2-SD 3.73Å
166D98.2Very high96.8Very high80 Ų8039.4 Ų39.443%0.42821%0.212SC..Hα-helixtrans-64.4-41.5177.7-66.2-21.4000111.6K163 K169 S170K163-D166 HydrophobicContact CB-CB 4.11Å; K163-D166 PolarHBondContact O-N 3.38Å; D166-K169 PolarHBondContact O-N 2.85Å; D166-K169 VanDerWaalsContact OD1-CE 3.3Å; D166-K169 WeakPolarHBondContact OD1-CE 3.42Å; D166-K169 IonicContact OD1-NZ 3.62Å; D166-K169 PolarHBondContact OD1-NZ 3.06Å; D166-S170 WeakPolarHBondContact O-CB 3.38Å; D166-S170 PolarHBondContact O-N 2.79Å
167H98.5Very high96.7Very high3 Ų339 Ų391%0.01422%0.217CC..Hα-helixtrans-59.8-51.3174.9-170.7-73.7000111.5Y43 H100 Y119 K163 W164 K169 S170 W171Y43-H167 HydrophobicContact CD2-CB 3.76Å; Y43-H167 AromaticContact CD2-CG 3.82Å; Y43-H167 HydrophobicContact CE2-CB 4.46Å; H100-H167 PolarHBondContact O-CD2 3.43Å; H100-H167 PolarHBondContact O-NE2 3.15Å; Y119-H167 AromaticContact CE2-CE1 3.79Å; Y119-H167 AromaticContact CE2-ND1 3.98Å; Y119-H167 AromaticContact CZ-ND1 3.91Å; Y119-H167 PolarHBondContact OH-ND1 2.75Å; K163-H167 PolarHBondContact O-N 3.38Å; W164-H167 PolarHBondContact O-N 3.4Å; H167-K169 PolarHBondContact O-N 3.1Å; H167-S170 PolarHBondContact O-N 2.65Å; H167-S170 PolarHBondContact O-OG 3.3Å; H167-W171 AromaticContact CE1-CD1 3.58Å; H167-W171 AromaticContact CE1-NE1 3.69Å; H167-W171 AromaticContact ND1-CD1 3.75Å; H167-W171 PolarHBondContact O-N 3.23Å
168V98Very high96.7Very high0 Ų046 Ų460%025%0.25CS..Hα-helixtrans-60.3-45.6178.6163.70000112.6Y119 T121 W164 T165 S170 W171 R172 M276 I281 F283Y119-V168 WeakPolarHBondContact OH-CA 3.19Å; T121-V168 HydrophobicContact CG2-CG2 4.14Å; W164-V168 HydrophobicContact CD2-CG2 3.89Å; W164-V168 HydrophobicContact CE3-CG2 4.22Å; W164-V168 HydrophobicContact CH2-CG1 4.42Å; W164-V168 HydrophobicContact CH2-CG2 3.99Å; W164-V168 HydrophobicContact CZ2-CG2 3.66Å; W164-V168 HydrophobicContact CZ3-CG2 4.25Å; W164-V168 WeakPolarHBondContact O-CB 3.32Å; W164-V168 WeakPolarHBondContact O-CG2 3.03Å; W164-V168 PolarHBondContact O-N 3.37Å; T165-V168 PolarHBondContact O-N 3Å; V168-S170 VanDerWaalsContact C-N 3.3Å; V168-S170 PolarHBondContact O-N 2.59Å; V168-W171 PolarHBondContact O-N 2.9Å; V168-R172 WeakPolarHBondContact O-CG 3.47Å; V168-R172 PolarHBondContact O-N 2.83Å; V168-M276 HydrophobicContact CG1-CE 4.19Å; V168-I281 HydrophobicContact CG1-CD1 4.21Å; V168-F283 HydrophobicContact CG1-CE2 4.38Å; V168-F283 HydrophobicContact CG1-CZ 3.65Å
169K97.9Very high96.8Very high70 Ų7042.2 Ų42.230%0.30423%0.231SC..Hα-helixtrans-60.6-41.7176.6-74.6176.3-63.4-1760111T165 D166 H167 W171 R172 E275 M276 T279 I281T165-K169 VanDerWaalsContact C-CE 3.44Å; T165-K169 WeakPolarHBondContact O-CB 3.32Å; T165-K169 WeakPolarHBondContact O-CE 3.29Å; T165-K169 VanDerWaalsContact O-CG 3.26Å; T165-K169 WeakPolarHBondContact O-CG 3.43Å; T165-K169 PolarHBondContact O-N 3.34Å; D166-K169 PolarHBondContact O-N 2.85Å; D166-K169 VanDerWaalsContact OD1-CE 3.3Å; D166-K169 WeakPolarHBondContact OD1-CE 3.42Å; D166-K169 IonicContact OD1-NZ 3.62Å; D166-K169 PolarHBondContact OD1-NZ 3.06Å; H167-K169 PolarHBondContact O-N 3.1Å; K169-W171 VanDerWaalsContact C-N 3.27Å; K169-W171 PolarHBondContact O-N 3.4Å; K169-R172 PolarHBondContact O-N 3.28Å; K169-E275 PolarHBondContact NZ-O 3.28Å; K169-M276 HydrophobicContact CD-SD 4.34Å; K169-M276 HydrophobicContact CG-CE 4.48Å; K169-M276 HydrophobicContact CG-SD 4.17Å; K169-T279 HydrophobicContact CD-CG2 3.95Å; K169-T279 HydrophobicContact CG-CG2 4.02Å; K169-I281 HydrophobicContact CG-CD1 4.25Å
170S97.8Very high96.9Very high24 Ų2442.8 Ų42.817%0.16823%0.234CC..Hα-helixtrans-60.4-35.8-178.479.60000113.3P102 Y103 D166 H167 V168P102-S170 WeakPolarHBondContact CB-OG 3.49Å; Y103-S170 WeakPolarHBondContact CB-O 3.28Å; Y103-S170 PolarHBondContact N-OG 3.15Å; Y103-S170 VanDerWaalsContact N-OG 3.17Å; D166-S170 WeakPolarHBondContact O-CB 3.38Å; D166-S170 PolarHBondContact O-N 2.79Å; H167-S170 PolarHBondContact O-N 2.65Å; H167-S170 PolarHBondContact O-OG 3.3Å; V168-S170 VanDerWaalsContact C-N 3.3Å; V168-S170 PolarHBondContact O-N 2.59Å
171W97.9Very high97Very high0 Ų043.5 Ų43.50%024%0.238CC..Hα-helixtrans-85.8-8.1-177.5-81.5100.9000114.5V41 M101 Y103 M106 F110 V117 Y119 H167 V168 K169 N173 L176 I180 Y182V41-W171 HydrophobicContact CB-CH2 4.29Å; V41-W171 HydrophobicContact CB-CZ2 4Å; V41-W171 HydrophobicContact CG1-CD2 4.15Å; V41-W171 VanDerWaalsContact CG1-CE2 3.42Å; V41-W171 HydrophobicContact CG1-CH2 4.3Å; V41-W171 HydrophobicContact CG1-CZ2 3.53Å; V41-W171 HydrophobicContact CG2-CH2 3.7Å; V41-W171 HydrophobicContact CG2-CZ2 3.73Å; V41-W171 HydrophobicContact CG2-CZ3 4.3Å; M101-W171 WeakPolarHBondContact O-CZ2 3.12Å; M101-W171 PolarHBondContact O-NE1 3.17Å; Y103-W171 HydrophobicContact CD2-CE3 4.02Å; Y103-W171 HydrophobicContact CD2-CH2 4.29Å; Y103-W171 AromaticContact CD2-CZ3 3.9Å; Y103-W171 HydrophobicContact CD2-CZ3 3.9Å; M106-W171 HydrophobicContact CE-CH2 4.12Å; M106-W171 HydrophobicContact CG-CH2 3.6Å; M106-W171 HydrophobicContact CG-CZ2 3.7Å; M106-W171 HydrophobicContact SD-CH2 3.71Å; M106-W171 HydrophobicContact SD-CZ2 3.61Å; F110-W171 HydrophobicContact CZ-CH2 4.3Å; F110-W171 HydrophobicContact CZ-CZ3 4.25Å; V117-W171 HydrophobicContact CG1-CE3 4.24Å; V117-W171 HydrophobicContact CG1-CH2 4.47Å; V117-W171 HydrophobicContact CG1-CZ3 3.76Å; V117-W171 HydrophobicContact CG2-CZ3 4.29Å; Y119-W171 HydrophobicContact CD1-CB 4.31Å; Y119-W171 HydrophobicContact CD2-CB 3.6Å; Y119-W171 AromaticContact CD2-CD1 3.99Å; Y119-W171 AromaticContact CD2-CD2 3.82Å; Y119-W171 HydrophobicContact CD2-CD2 3.82Å; Y119-W171 HydrophobicContact CD2-CE3 4.26Å; Y119-W171 AromaticContact CD2-CG 3.5Å; Y119-W171 HydrophobicContact CD2-CG 3.5Å; Y119-W171 VanDerWaalsContact CD2-CG 3.5Å; Y119-W171 HydrophobicContact CE1-CB 4.01Å; Y119-W171 HydrophobicContact CE2-CB 3.35Å; Y119-W171 AromaticContact CE2-CD1 3.28Å; Y119-W171 AromaticContact CE2-CD2 3.92Å; Y119-W171 HydrophobicContact CE2-CD2 3.92Å; Y119-W171 AromaticContact CE2-CG 3.18Å; Y119-W171 HydrophobicContact CE2-CG 3.18Å; Y119-W171 AromaticContact CE2-NE1 3.98Å; Y119-W171 HydrophobicContact CG-CB 4.11Å; Y119-W171 HydrophobicContact CG-CG 4.44Å; Y119-W171 AromaticContact CZ-CD1 3.95Å; Y119-W171 AromaticContact CZ-CG 3.88Å; H167-W171 AromaticContact CE1-CD1 3.58Å; H167-W171 AromaticContact CE1-NE1 3.69Å; H167-W171 AromaticContact ND1-CD1 3.75Å; H167-W171 PolarHBondContact O-N 3.23Å; V168-W171 PolarHBondContact O-N 2.9Å; K169-W171 VanDerWaalsContact C-N 3.27Å; K169-W171 PolarHBondContact O-N 3.4Å; W171-N173 PolarHBondContact O-N 3.08Å; W171-L176 HydrophobicContact CE3-CD1 4.18Å; W171-L176 HydrophobicContact CZ3-CD1 4.2Å; W171-I180 HydrophobicContact CE3-CD1 4.19Å; W171-Y182 PolarHBondContact O-OH 2.71Å
172R95.1Very high97Very high86 Ų8645.8 Ų45.833%0.32525%0.246SC..  trans-84.961.6173.4-70-75.3-169-171.54.6110.1V168 K169 I281V168-R172 WeakPolarHBondContact O-CG 3.47Å; V168-R172 PolarHBondContact O-N 2.83Å; K169-R172 PolarHBondContact O-N 3.28Å; R172-I281 HydrophobicContact CB-CD1 4.08Å; R172-I281 HydrophobicContact CB-CG1 4.33Å; R172-I281 HydrophobicContact CG-CD1 3.62Å; R172-I281 HydrophobicContact CG-CG1 3.81Å
173N92.3Very high97Very high37 Ų3745.5 Ų45.520%0.19824%0.243CC..  trans-105.1124.7-177-168-36.8000111.2Y103 W171 D175 L176Y103-N173 HydrophobicContact CD2-CB 4.5Å; Y103-N173 HydrophobicContact CE1-CB 4.35Å; Y103-N173 WeakPolarHBondContact CE1-ND2 3.42Å; Y103-N173 HydrophobicContact CE2-CB 4.28Å; Y103-N173 VanDerWaalsContact CZ-ND2 3.27Å; Y103-N173 PolarHBondContact OH-ND2 3.24Å; W171-N173 PolarHBondContact O-N 3.08Å; N173-D175 VanDerWaalsContact C-N 3.28Å; N173-D175 PolarHBondContact O-N 3.44Å; N173-D175 VanDerWaalsContact OD1-CB 3.28Å; N173-D175 WeakPolarHBondContact OD1-CB 3.44Å; N173-D175 PolarHBondContact OD1-N 2.99Å; N173-L176 HydrophobicContact CB-CD1 4.46Å; N173-L176 PolarHBondContact O-N 3.44Å
174S91.9Very high97Very high105 Ų10543 Ų4373%0.73423%0.233SC*.G310 helixtrans-66-26.6179.348.60000114L176 G177S174-L176 PolarHBondContact O-N 3.07Å; S174-G177 PolarHBondContact O-N 2.93Å
175D93.2Very high96.9Very high125 Ų12543.2 Ų43.267%0.66823%0.234SC*.G310 helixtrans-66.2-19.8-177.3-62-15.9000112.2N173 G177N173-D175 VanDerWaalsContact C-N 3.28Å; N173-D175 PolarHBondContact O-N 3.44Å; N173-D175 VanDerWaalsContact OD1-CB 3.28Å; N173-D175 WeakPolarHBondContact OD1-CB 3.44Å; N173-D175 PolarHBondContact OD1-N 2.99Å; D175-G177 VanDerWaalsContact C-N 3.32Å
176L96.4Very high96.9Very high4 Ų444.3 Ų44.32%0.02124%0.239CC..G310 helixtrans-72.6-24.1174.6-70.3171.6000112.6Y103 F110 W171 N173 S174 D178 R179 I180Y103-L176 HydrophobicContact CD2-CD1 4.1Å; Y103-L176 HydrophobicContact CE2-CD1 3.82Å; Y103-L176 HydrophobicContact CE2-CD2 4.03Å; Y103-L176 HydrophobicContact CE2-CG 3.91Å; F110-L176 HydrophobicContact CE1-CD2 4.15Å; F110-L176 HydrophobicContact CZ-CD2 3.85Å; W171-L176 HydrophobicContact CE3-CD1 4.18Å; W171-L176 HydrophobicContact CZ3-CD1 4.2Å; N173-L176 HydrophobicContact CB-CD1 4.46Å; N173-L176 PolarHBondContact O-N 3.44Å; S174-L176 PolarHBondContact O-N 3.07Å; L176-D178 PolarHBondContact O-N 3.32Å; L176-R179 WeakPolarHBondContact O-CA 3.26Å; L176-R179 WeakPolarHBondContact O-CB 3.38Å; L176-R179 PolarHBondContact O-N 3.09Å; L176-I180 HydrophobicContact CB-CB 3.95Å; L176-I180 HydrophobicContact CB-CG2 3.52Å; L176-I180 HydrophobicContact CD1-CB 4.12Å; L176-I180 HydrophobicContact CD1-CD1 3.6Å; L176-I180 HydrophobicContact CD1-CG1 4.46Å; L176-I180 HydrophobicContact CD1-CG2 4.24Å
177G96.4Very high96.8Very high46 Ų4643.2 Ų43.247%0.47423%0.232SC..G310 helixtrans44.9-126.4178.700000113.2S174 D175 R179 I180S174-G177 PolarHBondContact O-N 2.93Å; D175-G177 VanDerWaalsContact C-N 3.32Å; G177-R179 PolarHBondContact O-N 3.46Å; G177-I180 WeakPolarHBondContact O-CG2 3.29Å
178D96.6Very high96.7Very high159 Ų15943.1 Ų43.185%0.8523%0.231SC*.G310 helixtrans-78.20.7179.7-60.2-31.8000114L176 I180 F202L176-D178 PolarHBondContact O-N 3.32Å; D178-I180 VanDerWaalsContact C-N 3.3Å; D178-F202 WeakPolarHBondContact O-CE2 3.38Å
179R97.9Very high96.6Very high46 Ų4646.5 Ų46.517%0.17425%0.248CC..G310 helixtrans-80.7-9.1175-61.7169.456.6-169.52.6112.7F110 F111 S113 A115 K116 V117 L176 G177 F202F110-R179 PolarHBondContact O-NH2 3.46Å; F110-R179 VanDerWaalsContact O-NH2 3.17Å; F111-R179 PolarHBondContact O-NH1 3.14Å; S113-R179 PolarHBondContact O-NH1 3.01Å; S113-R179 PolarHBondContact O-NH2 3.26Å; S113-R179 VanDerWaalsContact O-NH2 3.17Å; S113-R179 PolarHBondContact OG-NH2 2.91Å; S113-R179 VanDerWaalsContact OG-NH2 3.07Å; A115-R179 PolarHBondContact O-NE 3.05Å; A115-R179 PolarHBondContact O-NH2 3.47Å; A115-R179 VanDerWaalsContact O-NH2 3.08Å; K116-R179 CarbonylContact C-O 3.48Å; K116-R179 WeakPolarHBondContact CA-O 3.48Å; V117-R179 PolarHBondContact N-O 3.48Å; L176-R179 WeakPolarHBondContact O-CA 3.26Å; L176-R179 WeakPolarHBondContact O-CB 3.38Å; L176-R179 PolarHBondContact O-N 3.09Å; G177-R179 PolarHBondContact O-N 3.46Å; R179-F202 WeakPolarHBondContact O-CZ 3.47Å
180I98.7Very high96.5Very high15 Ų1552.1 Ų52.18%0.07727%0.273CS..EExtended strand (participates in β ladder)trans-118.3129.9-179.8-174.1161000112.1V117 W171 L176 G177 D178 Y182V117-I180 HydrophobicContact CB-CB 4.22Å; V117-I180 HydrophobicContact CB-CD1 4.34Å; V117-I180 HydrophobicContact CB-CG1 4.09Å; V117-I180 HydrophobicContact CG1-CD1 4Å; V117-I180 HydrophobicContact CG1-CG1 4.12Å; V117-I180 CarbonylContact O-C 3.54Å; V117-I180 VanDerWaalsContact O-CA 3.31Å; V117-I180 WeakPolarHBondContact O-CA 3.24Å; W171-I180 HydrophobicContact CE3-CD1 4.19Å; L176-I180 HydrophobicContact CB-CB 3.95Å; L176-I180 HydrophobicContact CB-CG2 3.52Å; L176-I180 HydrophobicContact CD1-CB 4.12Å; L176-I180 HydrophobicContact CD1-CD1 3.6Å; L176-I180 HydrophobicContact CD1-CG1 4.46Å; L176-I180 HydrophobicContact CD1-CG2 4.24Å; G177-I180 WeakPolarHBondContact O-CG2 3.29Å; D178-I180 VanDerWaalsContact C-N 3.3Å; I180-Y182 HydrophobicContact CD1-CD1 4.34Å; I180-Y182 HydrophobicContact CD1-CE1 3.6Å; I180-Y182 HydrophobicContact CD1-CE2 4.25Å; I180-Y182 HydrophobicContact CG1-CD1 4.47Å; I180-Y182 HydrophobicContact CG1-CD2 4.44Å; I180-Y182 HydrophobicContact CG1-CE1 4.08Å; I180-Y182 HydrophobicContact CG1-CE2 4.04Å; I180-Y182 HydrophobicContact CG2-CE2 3.73Å
181L98.6Very high96.4Very high25 Ų2555.1 Ų55.113%0.13129%0.287CS..EExtended strand (participates in β ladder)trans-109123.4168.8179.463.8000109.4V117 I118 Y119 I183 L199 F202V117-L181 PolarHBondContact O-N 2.92Å; I118-L181 WeakPolarHBondContact CA-O 3.37Å; Y119-L181 PolarHBondContact N-O 3.02Å; L181-I183 HydrophobicContact CD2-CD1 3.89Å; L181-I183 HydrophobicContact CD2-CG1 4.24Å; L181-I183 HydrophobicContact CG-CD1 4.26Å; L181-I183 HydrophobicContact CG-CG1 4.11Å; L181-L199 HydrophobicContact CD2-CD2 3.85Å; L181-L199 HydrophobicContact CD2-CG 4.3Å; L181-F202 HydrophobicContact CB-CD1 3.82Å; L181-F202 HydrophobicContact CB-CD2 3.91Å; L181-F202 HydrophobicContact CB-CE1 3.77Å; L181-F202 HydrophobicContact CB-CE2 3.85Å; L181-F202 HydrophobicContact CB-CG 3.88Å; L181-F202 HydrophobicContact CB-CZ 3.78Å; L181-F202 HydrophobicContact CD2-CB 3.87Å; L181-F202 HydrophobicContact CD2-CD1 3.95Å; L181-F202 HydrophobicContact CD2-CG 3.89Å; L181-F202 HydrophobicContact CG-CG 4.42Å
182Y98.2Very high96.4Very high57 Ų5756.1 Ų56.122%0.22429%0.292CS..EExtended strand (participates in β ladder)trans-92.9129174-60-83.4000110.4Y119 W171 I180 R198Y119-Y182 AromaticContact CD1-CD1 3.82Å; Y119-Y182 HydrophobicContact CD1-CD1 3.82Å; Y119-Y182 HydrophobicContact CD1-CE1 4.08Å; Y119-Y182 HydrophobicContact CG-CD1 4.28Å; Y119-Y182 HydrophobicContact CG-CE1 4.39Å; W171-Y182 PolarHBondContact O-OH 2.71Å; I180-Y182 HydrophobicContact CD1-CD1 4.34Å; I180-Y182 HydrophobicContact CD1-CE1 3.6Å; I180-Y182 HydrophobicContact CD1-CE2 4.25Å; I180-Y182 HydrophobicContact CG1-CD1 4.47Å; I180-Y182 HydrophobicContact CG1-CD2 4.44Å; I180-Y182 HydrophobicContact CG1-CE1 4.08Å; I180-Y182 HydrophobicContact CG1-CE2 4.04Å; I180-Y182 HydrophobicContact CG2-CE2 3.73Å; Y182-R198 PolarHBondContact O-NH2 3.01Å
183I97.8Very high96.5Very high0 Ų053.9 Ų53.90%028%0.284CS..EExtended strand (participates in β ladder)trans-130.9148.1176.3-64.3170.2000108.1I118 Y119 V120 T121 L181 E187 M188 V195 L199I118-I183 HydrophobicContact CG2-CD1 3.85Å; Y119-I183 PolarHBondContact O-N 3.03Å; V120-I183 VanDerWaalsContact CA-O 3.3Å; V120-I183 WeakPolarHBondContact CA-O 3.41Å; V120-I183 HydrophobicContact CG2-CB 4.41Å; T121-I183 PolarHBondContact N-O 2.7Å; L181-I183 HydrophobicContact CD2-CD1 3.89Å; L181-I183 HydrophobicContact CD2-CG1 4.24Å; L181-I183 HydrophobicContact CG-CD1 4.26Å; L181-I183 HydrophobicContact CG-CG1 4.11Å; I183-E187 WeakPolarHBondContact CA-OE2 3.43Å; I183-M188 HydrophobicContact CG2-CG 3.77Å; I183-M188 HydrophobicContact CG2-SD 4.23Å; I183-V195 HydrophobicContact CD1-CG1 3.85Å; I183-V195 HydrophobicContact CG1-CG1 4.41Å; I183-V195 HydrophobicContact CG2-CG1 4.02Å; I183-L199 HydrophobicContact CD1-CD1 4.06Å; I183-L199 HydrophobicContact CD1-CD2 3.66Å; I183-L199 HydrophobicContact CD1-CG 3.77Å
184T98.1Very high96.7Very high11 Ų1152.9 Ų52.97%0.06728%0.282CS..EExtended strand (participates in β ladder)trans-109.4152165.788.30000113T121 E186 E187 M188 P284 W285T121-T184 CarbonylContact O-C 3.51Å; T121-T184 WeakPolarHBondContact O-CA 3.35Å; T184-E186 VanDerWaalsContact CB-OE2 3.26Å; T184-E186 WeakPolarHBondContact CB-OE2 3.35Å; T184-E186 PolarHBondContact O-N 2.86Å; T184-E186 PolarHBondContact OG1-N 3.16Å; T184-E186 PolarHBondContact OG1-OE2 2.88Å; T184-E186 VanDerWaalsContact OG1-OE2 3.09Å; T184-E187 PolarHBondContact N-OE2 3.14Å; T184-E187 WeakPolarHBondContact O-CB 3.5Å; T184-E187 PolarHBondContact O-N 2.95Å; T184-E187 PolarHBondContact OG1-N 3.17Å; T184-E187 VanDerWaalsContact OG1-N 3.13Å; T184-M188 PolarHBondContact O-N 3.25Å; T184-M188 VanDerWaalsContact O-N 3.16Å; T184-P284 HydrophobicContact CG2-CG 3.99Å; T184-W285 HydrophobicContact CG2-CZ3 4.07Å
185Y97.9Very high97Very high14 Ų1448.1 Ų48.16%0.05525%0.249CC..Hα-helixtrans-57.1-36.1173.3-176.2-87.1000111.8W50 T121 R122 M188 I189 G251W50-Y185 HydrophobicContact CE3-CD2 4.08Å; W50-Y185 AromaticContact CE3-CE2 3.67Å; W50-Y185 HydrophobicContact CE3-CE2 3.67Å; W50-Y185 HydrophobicContact CZ3-CD2 4.23Å; W50-Y185 AromaticContact CZ3-CE2 3.82Å; W50-Y185 HydrophobicContact CZ3-CE2 3.82Å; T121-Y185 PolarHBondContact O-N 3.35Å; R122-Y185 HydrophobicContact CB-CG 4.42Å; R122-Y185 HydrophobicContact CG-CD1 4.18Å; R122-Y185 HydrophobicContact CG-CG 3.97Å; Y185-M188 HydrophobicContact CD2-CE 3.91Å; Y185-M188 HydrophobicContact CG-CE 4.42Å; Y185-M188 WeakPolarHBondContact O-CB 3.45Å; Y185-M188 PolarHBondContact O-N 3.3Å; Y185-I189 HydrophobicContact CD1-CG1 3.81Å; Y185-I189 HydrophobicContact CE1-CD1 3.78Å; Y185-I189 HydrophobicContact CE1-CG1 3.37Å; Y185-I189 WeakPolarHBondContact O-CG1 3.28Å; Y185-I189 PolarHBondContact O-N 3.36Å; Y185-G251 VanDerWaalsContact OH-CA 3.3Å; Y185-G251 WeakPolarHBondContact OH-CA 3.31Å; Y185-G251 PolarHBondContact OH-O 2.85Å
186E97.6Very high97.3Very high23 Ų2342.2 Ų42.211%0.10722%0.217CC..Hα-helixtrans-66.1-39.8178.1-60.871.1-160.900111.3N123 T184 I189 K190 A253 W285N123-E186 WeakPolarHBondContact CB-OE1 3.3Å; N123-E186 PolarHBondContact N-OE1 3.05Å; T184-E186 VanDerWaalsContact CB-OE2 3.26Å; T184-E186 WeakPolarHBondContact CB-OE2 3.35Å; T184-E186 PolarHBondContact O-N 2.86Å; T184-E186 PolarHBondContact OG1-N 3.16Å; T184-E186 PolarHBondContact OG1-OE2 2.88Å; T184-E186 VanDerWaalsContact OG1-OE2 3.09Å; E186-I189 PolarHBondContact O-N 3.28Å; E186-K190 VanDerWaalsContact O-CB 3.26Å; E186-K190 WeakPolarHBondContact O-CB 3.44Å; E186-K190 PolarHBondContact O-N 3.41Å; E186-A253 HydrophobicContact CG-CB 4.09Å; E186-W285 VanDerWaalsContact CD-CZ3 3.49Å; E186-W285 HydrophobicContact CG-CE3 4.02Å; E186-W285 WeakPolarHBondContact OE2-CZ3 3.3Å
187E96.5Very high97.4Very high58 Ų5844.8 Ų44.827%0.27123%0.229SC..Hα-helixtrans-60.8-45.2170.9-70.1176.9121.200111.1I183 T184 I189 K190 D191 V195 R198I183-E187 WeakPolarHBondContact CA-OE2 3.43Å; T184-E187 PolarHBondContact N-OE2 3.14Å; T184-E187 WeakPolarHBondContact O-CB 3.5Å; T184-E187 PolarHBondContact O-N 2.95Å; T184-E187 PolarHBondContact OG1-N 3.17Å; T184-E187 VanDerWaalsContact OG1-N 3.13Å; E187-I189 VanDerWaalsContact C-N 3.34Å; E187-I189 PolarHBondContact O-N 3.45Å; E187-K190 PolarHBondContact O-N 2.9Å; E187-D191 CarbonylContact O-C 3.31Å; E187-D191 PolarHBondContact O-N 3.49Å; E187-V195 HydrophobicContact CB-CG2 4.01Å; E187-R198 IonicContact OE1-CZ 3.54Å; E187-R198 IonicContact OE1-NH1 3.06Å; E187-R198 PolarHBondContact OE1-NH1 3.33Å; E187-R198 IonicContact OE2-NH1 3.87Å
188M96.8Very high97.5Very high1 Ų146.4 Ų46.41%0.00522%0.221CC..Hα-helixtrans-63.2-38.1178.6-64.1-170.1-65.200112.6W50 M51 I54 V120 I183 T184 Y185 L192 V195W50-M188 HydrophobicContact CD2-CE 4.28Å; W50-M188 HydrophobicContact CD2-SD 4.29Å; W50-M188 HydrophobicContact CE3-CB 4.04Å; W50-M188 HydrophobicContact CE3-CE 3.61Å; W50-M188 HydrophobicContact CE3-SD 4.1Å; W50-M188 HydrophobicContact CH2-CB 3.67Å; W50-M188 HydrophobicContact CZ2-CB 4.31Å; W50-M188 HydrophobicContact CZ3-CB 3.52Å; W50-M188 HydrophobicContact CZ3-CE 4.11Å; M51-M188 HydrophobicContact SD-SD 3.77Å; I54-M188 HydrophobicContact CD1-SD 4.41Å; V120-M188 HydrophobicContact CG1-CE 3.79Å; I183-M188 HydrophobicContact CG2-CG 3.77Å; I183-M188 HydrophobicContact CG2-SD 4.23Å; T184-M188 PolarHBondContact O-N 3.25Å; T184-M188 VanDerWaalsContact O-N 3.16Å; Y185-M188 HydrophobicContact CD2-CE 3.91Å; Y185-M188 HydrophobicContact CG-CE 4.42Å; Y185-M188 WeakPolarHBondContact O-CB 3.45Å; Y185-M188 PolarHBondContact O-N 3.3Å; M188-L192 HydrophobicContact CB-CD1 4.46Å; M188-L192 WeakPolarHBondContact O-CA 3.39Å; M188-L192 WeakPolarHBondContact O-CB 3.29Å; M188-L192 PolarHBondContact O-N 3.13Å; M188-V195 HydrophobicContact CG-CG1 4.07Å; M188-V195 HydrophobicContact CG-CG2 4.35Å
189I95.3Very high97.5Very high70 Ų7038.9 Ų38.936%0.35918%0.181SC..Hα-helixtrans-68.4-41.3175.8-69.8-68.6000111.5W50 Y185 E186 E187 G251W50-I189 HydrophobicContact CH2-CD1 3.65Å; W50-I189 HydrophobicContact CH2-CG1 4.14Å; W50-I189 HydrophobicContact CZ3-CD1 3.67Å; W50-I189 HydrophobicContact CZ3-CG1 3.95Å; Y185-I189 HydrophobicContact CD1-CG1 3.81Å; Y185-I189 HydrophobicContact CE1-CD1 3.78Å; Y185-I189 HydrophobicContact CE1-CG1 3.37Å; Y185-I189 WeakPolarHBondContact O-CG1 3.28Å; Y185-I189 PolarHBondContact O-N 3.36Å; E186-I189 PolarHBondContact O-N 3.28Å; E187-I189 VanDerWaalsContact C-N 3.34Å; E187-I189 PolarHBondContact O-N 3.45Å; I189-G251 WeakPolarHBondContact CD1-O 3.48Å
190K95.3Very high97.6Very high189 Ų18936.8 Ų36.882%0.82217%0.173SC*.Hα-helixtrans-72.1-45-175.9-176.6178.4179.7179.70112.2E186 E187E186-K190 VanDerWaalsContact O-CB 3.26Å; E186-K190 WeakPolarHBondContact O-CB 3.44Å; E186-K190 PolarHBondContact O-N 3.41Å; E187-K190 PolarHBondContact O-N 2.9Å
191D96.5Very high97.5Very high86 Ų8642.5 Ų42.546%0.4619%0.194SC..  trans-152.579.4-177.1179.815.8000111E187 R193 G194 V195E187-D191 CarbonylContact O-C 3.31Å; E187-D191 PolarHBondContact O-N 3.49Å; D191-R193 PolarHBondContact O-N 2.94Å; D191-R193 PolarHBondContact OD1-N 3.41Å; D191-G194 PolarHBondContact O-N 3.14Å; D191-G194 PolarHBondContact OD1-N 2.95Å; D191-G194 WeakPolarHBondContact OD2-CA 3.25Å; D191-G194 PolarHBondContact OD2-N 3.09Å; D191-V195 WeakPolarHBondContact O-CG2 3.46Å; D191-V195 PolarHBondContact O-N 3.41Å; D191-V195 VanDerWaalsContact O-N 3.14Å
192L97Very high97.5Very high21 Ų2143 Ų4311%0.1120%0.195CC..Hα-helixtrans-59.1-37.6176.8-178.461.3000111.9W50 I54 M188 V195 L196 A216 C219W50-L192 HydrophobicContact CZ2-CD1 3.91Å; W50-L192 HydrophobicContact CZ2-CD2 4Å; W50-L192 HydrophobicContact CZ2-CG 4.41Å; I54-L192 HydrophobicContact CD1-CD1 3.84Å; M188-L192 HydrophobicContact CB-CD1 4.46Å; M188-L192 WeakPolarHBondContact O-CA 3.39Å; M188-L192 WeakPolarHBondContact O-CB 3.29Å; M188-L192 PolarHBondContact O-N 3.13Å; L192-V195 PolarHBondContact O-N 3.22Å; L192-L196 HydrophobicContact CD1-CG 4.38Å; L192-L196 HydrophobicContact CG-CD1 4.07Å; L192-L196 HydrophobicContact CG-CG 4.34Å; L192-L196 VanDerWaalsContact O-CG 3.31Å; L192-L196 WeakPolarHBondContact O-CG 3.01Å; L192-L196 PolarHBondContact O-N 3.41Å; L192-A216 HydrophobicContact CD2-CB 4.32Å; L192-A216 WeakPolarHBondContact CD2-O 3.35Å; L192-C219 HydrophobicContact CD2-CB 3.95Å
193R97.2Very high97.5Very high39 Ų3940.9 Ų40.915%0.14719%0.187CC..Hα-helixtrans-66.3-41.9-176.6173.754.9-171.872.1-1.4111.4D191 L196 E197 E209 L212 D213 A216D191-R193 PolarHBondContact O-N 2.94Å; D191-R193 PolarHBondContact OD1-N 3.41Å; R193-L196 PolarHBondContact O-N 3.33Å; R193-E197 IonicContact CZ-OE2 2.82Å; R193-E197 IonicContact NH1-OE2 3.77Å; R193-E197 PolarHBondContact NH1-OE2 3.34Å; R193-E197 IonicContact NH2-OE2 2.75Å; R193-E197 PolarHBondContact O-N 2.89Å; R193-E197 VanDerWaalsContact O-N 3.17Å; R193-E209 IonicContact CZ-OE2 2.79Å; R193-E209 IonicContact NH2-OE1 3.06Å; R193-E209 PolarHBondContact NH2-OE1 3.25Å; R193-E209 IonicContact NH2-OE2 3.97Å; R193-E209 PolarHBondContact NH2-OE2 3.01Å; R193-L212 VanDerWaalsContact CZ-CB 3.5Å; R193-L212 VanDerWaalsContact CZ-CD1 3.47Å; R193-L212 VanDerWaalsContact NH2-CD1 3.29Å; R193-D213 VanDerWaalsContact CD-OD1 3.26Å; R193-D213 WeakPolarHBondContact CD-OD1 3.47Å; R193-D213 IonicContact NE-OD1 2.86Å; R193-D213 PolarHBondContact NE-OD1 3.39Å; R193-A216 HydrophobicContact CB-CB 4.36Å
194G97.8Very high97.5Very high17 Ų1743.2 Ų43.218%0.17521%0.211CC..Hα-helixtrans-66.7-36.4172.700000113.2D191 E197 R198D191-G194 PolarHBondContact O-N 3.14Å; D191-G194 PolarHBondContact OD1-N 2.95Å; D191-G194 WeakPolarHBondContact OD2-CA 3.25Å; D191-G194 PolarHBondContact OD2-N 3.09Å; G194-E197 PolarHBondContact O-N 3.26Å; G194-R198 WeakPolarHBondContact O-CG 3.26Å; G194-R198 PolarHBondContact O-N 3.06Å; G194-R198 VanDerWaalsContact O-N 3.13Å
195V98.1Very high97.4Very high4 Ų447.6 Ų47.62%0.02423%0.226CC..Hα-helixtrans-65.4-42.6173.8173.90000111.6I183 E187 M188 D191 L192 E197 R198 L199I183-V195 HydrophobicContact CD1-CG1 3.85Å; I183-V195 HydrophobicContact CG1-CG1 4.41Å; I183-V195 HydrophobicContact CG2-CG1 4.02Å; E187-V195 HydrophobicContact CB-CG2 4.01Å; M188-V195 HydrophobicContact CG-CG1 4.07Å; M188-V195 HydrophobicContact CG-CG2 4.35Å; D191-V195 WeakPolarHBondContact O-CG2 3.46Å; D191-V195 PolarHBondContact O-N 3.41Å; D191-V195 VanDerWaalsContact O-N 3.14Å; L192-V195 PolarHBondContact O-N 3.22Å; V195-E197 VanDerWaalsContact C-N 3.28Å; V195-E197 PolarHBondContact O-N 3.43Å; V195-R198 PolarHBondContact O-N 2.92Å; V195-L199 HydrophobicContact CG1-CD1 3.93Å; V195-L199 HydrophobicContact CG1-CG 4.39Å; V195-L199 WeakPolarHBondContact O-CG 3.43Å; V195-L199 PolarHBondContact O-N 3.21Å
196L98.4Very high97.3Very high1 Ų152.7 Ų52.71%0.00526%0.255CS..Hα-helixtrans-60.6-38.3176.4-75.4169.1000112.1I54 V58 L192 R193 L199 S200 L212 V215 A216I54-L196 HydrophobicContact CB-CD2 4.45Å; I54-L196 HydrophobicContact CG1-CD2 4.34Å; I54-L196 HydrophobicContact CG2-CD2 3.43Å; I54-L196 VanDerWaalsContact CG2-CD2 3.43Å; V58-L196 HydrophobicContact CG2-CD2 4.02Å; L192-L196 HydrophobicContact CD1-CG 4.38Å; L192-L196 HydrophobicContact CG-CD1 4.07Å; L192-L196 HydrophobicContact CG-CG 4.34Å; L192-L196 VanDerWaalsContact O-CG 3.31Å; L192-L196 WeakPolarHBondContact O-CG 3.01Å; L192-L196 PolarHBondContact O-N 3.41Å; R193-L196 PolarHBondContact O-N 3.33Å; L196-L199 PolarHBondContact O-N 3.38Å; L196-S200 WeakPolarHBondContact O-CB 3.41Å; L196-S200 PolarHBondContact O-N 2.89Å; L196-L212 HydrophobicContact CB-CD2 3.81Å; L196-V215 HydrophobicContact CD1-CB 4.22Å; L196-V215 HydrophobicContact CD1-CG1 3.86Å; L196-V215 HydrophobicContact CD2-CG1 3.74Å; L196-V215 HydrophobicContact CG-CG1 4.48Å; L196-A216 HydrophobicContact CD1-CB 3.69Å
197E98.3Very high97.2Very high58 Ų5852.8 Ų52.827%0.27126%0.256SS..Hα-helixtrans-65.3-44.3176.1-157.6-178.7147.600112R193 G194 V195 L199 S200 R201 L212R193-E197 IonicContact CZ-OE2 2.82Å; R193-E197 IonicContact NH1-OE2 3.77Å; R193-E197 PolarHBondContact NH1-OE2 3.34Å; R193-E197 IonicContact NH2-OE2 2.75Å; R193-E197 PolarHBondContact O-N 2.89Å; R193-E197 VanDerWaalsContact O-N 3.17Å; G194-E197 PolarHBondContact O-N 3.26Å; V195-E197 VanDerWaalsContact C-N 3.28Å; V195-E197 PolarHBondContact O-N 3.43Å; E197-L199 VanDerWaalsContact C-N 3.35Å; E197-L199 PolarHBondContact O-N 3.36Å; E197-S200 PolarHBondContact O-N 2.82Å; E197-R201 WeakPolarHBondContact O-CG 3.28Å; E197-R201 PolarHBondContact O-N 3.07Å; E197-R201 IonicContact OE1-CZ 3.39Å; E197-R201 IonicContact OE1-NE 3.88Å; E197-R201 IonicContact OE1-NH2 2.87Å; E197-R201 PolarHBondContact OE1-NH2 3.18Å; E197-R201 IonicContact OE2-NH2 2.82Å; E197-L212 HydrophobicContact CB-CD1 4.33Å; E197-L212 HydrophobicContact CG-CD1 4.08Å
198R98.3Very high97.3Very high80 Ų8052.9 Ų52.930%0.30226%0.263SS..Hα-helixtrans-59.9-44.6173.9-73.3170.359-165-4.2111.4Y182 E187 G194 V195 F202Y182-R198 PolarHBondContact O-NH2 3.01Å; E187-R198 IonicContact OE1-CZ 3.54Å; E187-R198 IonicContact OE1-NH1 3.06Å; E187-R198 PolarHBondContact OE1-NH1 3.33Å; E187-R198 IonicContact OE2-NH1 3.87Å; G194-R198 WeakPolarHBondContact O-CG 3.26Å; G194-R198 PolarHBondContact O-N 3.06Å; G194-R198 VanDerWaalsContact O-N 3.13Å; V195-R198 PolarHBondContact O-N 2.92Å; R198-F202 VanDerWaalsContact O-CB 3.22Å; R198-F202 WeakPolarHBondContact O-CB 3.26Å; R198-F202 PolarHBondContact O-N 3.3Å
199L98.4Very high97.3Very high1 Ų158.3 Ų58.31%0.00529%0.288CS..Hα-helixtrans-62.6-46.5176.5-79.8167.1000111.9M51 I54 I118 L181 I183 V195 L196 E197 R201 F202 L203M51-L199 HydrophobicContact CE-CD1 3.9Å; M51-L199 HydrophobicContact CE-CD2 4.14Å; I54-L199 HydrophobicContact CG2-CD1 3.71Å; I118-L199 HydrophobicContact CD1-CD2 3.52Å; I118-L199 HydrophobicContact CG1-CD2 3.83Å; I118-L199 HydrophobicContact CG2-CD2 4.06Å; L181-L199 HydrophobicContact CD2-CD2 3.85Å; L181-L199 HydrophobicContact CD2-CG 4.3Å; I183-L199 HydrophobicContact CD1-CD1 4.06Å; I183-L199 HydrophobicContact CD1-CD2 3.66Å; I183-L199 HydrophobicContact CD1-CG 3.77Å; V195-L199 HydrophobicContact CG1-CD1 3.93Å; V195-L199 HydrophobicContact CG1-CG 4.39Å; V195-L199 WeakPolarHBondContact O-CG 3.43Å; V195-L199 PolarHBondContact O-N 3.21Å; L196-L199 PolarHBondContact O-N 3.38Å; E197-L199 VanDerWaalsContact C-N 3.35Å; E197-L199 PolarHBondContact O-N 3.36Å; L199-R201 PolarHBondContact O-N 3.35Å; L199-F202 PolarHBondContact O-N 3.48Å; L199-L203 WeakPolarHBondContact O-CB 3.39Å; L199-L203 VanDerWaalsContact O-CG 3.28Å; L199-L203 WeakPolarHBondContact O-CG 3.43Å; L199-L203 PolarHBondContact O-N 2.83Å
200S98.3Very high97.4Very high2 Ų262.2 Ų62.21%0.01431%0.305CS..Hα-helixtrans-56.8-48.4178.1175.60000111.8L196 E197 L203 G204 R205 D206 L207L196-S200 WeakPolarHBondContact O-CB 3.41Å; L196-S200 PolarHBondContact O-N 2.89Å; E197-S200 PolarHBondContact O-N 2.82Å; S200-L203 PolarHBondContact O-N 2.9Å; S200-G204 PolarHBondContact O-N 2.98Å; S200-G204 VanDerWaalsContact O-N 3.08Å; S200-R205 PolarHBondContact O-N 3.11Å; S200-D206 WeakPolarHBondContact OG-CA 3.46Å; S200-D206 PolarHBondContact OG-N 3.05Å; S200-L207 WeakPolarHBondContact OG-CG 3.36Å; S200-L207 PolarHBondContact OG-N 3.28Å
201R98.3Very high97.6Very high136 Ų13654.1 Ų54.151%0.51327%0.271SS..Hα-helixtrans-64.9-46.2175.8-69-171.3-120.2120.3-9.5111.9E197 L199 L203 G204E197-R201 WeakPolarHBondContact O-CG 3.28Å; E197-R201 PolarHBondContact O-N 3.07Å; E197-R201 IonicContact OE1-CZ 3.39Å; E197-R201 IonicContact OE1-NE 3.88Å; E197-R201 IonicContact OE1-NH2 2.87Å; E197-R201 PolarHBondContact OE1-NH2 3.18Å; E197-R201 IonicContact OE2-NH2 2.82Å; L199-R201 PolarHBondContact O-N 3.35Å; R201-L203 VanDerWaalsContact C-N 3.28Å; R201-L203 PolarHBondContact O-N 3.38Å; R201-G204 PolarHBondContact O-N 3.13Å
202F98.6Very high97.6Very high34 Ų3450.1 Ų50.115%0.14925%0.25CS..Hα-helixtrans-59.7-38.2178.3174.6-108.6000112.4K116 V117 I118 D178 R179 L181 R198 L199 G204K116-F202 HydrophobicContact CB-CE1 3.85Å; K116-F202 HydrophobicContact CB-CZ 3.84Å; K116-F202 HydrophobicContact CD-CE1 4.12Å; K116-F202 HydrophobicContact CD-CZ 4.15Å; K116-F202 WeakPolarHBondContact CE-O 3.45Å; K116-F202 HydrophobicContact CG-CE1 4.35Å; K116-F202 HydrophobicContact CG-CZ 4.1Å; K116-F202 PolarHBondContact NZ-O 3.45Å; V117-F202 WeakPolarHBondContact O-CZ 3.22Å; I118-F202 HydrophobicContact CG1-CD1 4.31Å; I118-F202 HydrophobicContact CG1-CE1 3.98Å; D178-F202 WeakPolarHBondContact O-CE2 3.38Å; R179-F202 WeakPolarHBondContact O-CZ 3.47Å; L181-F202 HydrophobicContact CB-CD1 3.82Å; L181-F202 HydrophobicContact CB-CD2 3.91Å; L181-F202 HydrophobicContact CB-CE1 3.77Å; L181-F202 HydrophobicContact CB-CE2 3.85Å; L181-F202 HydrophobicContact CB-CG 3.88Å; L181-F202 HydrophobicContact CB-CZ 3.78Å; L181-F202 HydrophobicContact CD2-CB 3.87Å; L181-F202 HydrophobicContact CD2-CD1 3.95Å; L181-F202 HydrophobicContact CD2-CG 3.89Å; L181-F202 HydrophobicContact CG-CG 4.42Å; R198-F202 VanDerWaalsContact O-CB 3.22Å; R198-F202 WeakPolarHBondContact O-CB 3.26Å; R198-F202 PolarHBondContact O-N 3.3Å; L199-F202 PolarHBondContact O-N 3.48Å; F202-G204 VanDerWaalsContact C-N 3.33Å
203L98.1Very high97.7Very high14 Ų1453.3 Ų53.37%0.07327%0.267CS..THydrogen-bonded Turntrans-84.6-3.3178.2-63.5178.4000113.5I38 V58 L59 K116 I118 L199 S200 R201 R205I38-L203 HydrophobicContact CD1-CD2 3.59Å; I38-L203 HydrophobicContact CG1-CD2 4.15Å; I38-L203 HydrophobicContact CG2-CD2 3.96Å; V58-L203 HydrophobicContact CB-CD1 4.29Å; V58-L203 HydrophobicContact CG1-CD1 3.81Å; L59-L203 HydrophobicContact CD2-CD1 4.11Å; K116-L203 HydrophobicContact CD-CD2 4.22Å; I118-L203 HydrophobicContact CD1-CD1 4.44Å; I118-L203 HydrophobicContact CD1-CD2 4.47Å; L199-L203 WeakPolarHBondContact O-CB 3.39Å; L199-L203 VanDerWaalsContact O-CG 3.28Å; L199-L203 WeakPolarHBondContact O-CG 3.43Å; L199-L203 PolarHBondContact O-N 2.83Å; S200-L203 PolarHBondContact O-N 2.9Å; R201-L203 VanDerWaalsContact C-N 3.28Å; R201-L203 PolarHBondContact O-N 3.38Å; L203-R205 HydrophobicContact CB-CG 4.16Å
204G97Very high97.6Very high48 Ų4857 Ų5750%0.49528%0.281SS..THydrogen-bonded Turntrans67.536.3179.200000113.4S200 R201 F202S200-G204 PolarHBondContact O-N 2.98Å; S200-G204 VanDerWaalsContact O-N 3.08Å; R201-G204 PolarHBondContact O-N 3.13Å; F202-G204 VanDerWaalsContact C-N 3.33Å
205R96.4Very high97.6Very high103 Ų10356.2 Ų56.239%0.38927%0.273SS..  trans-104.2-25-178.2-62.6-61.4-178.4-174.82.8113.9V58 P94 S200 L203 L207V58-R205 HydrophobicContact CG1-CB 4.38Å; V58-R205 HydrophobicContact CG1-CG 4.31Å; V58-R205 WeakPolarHBondContact O-CG 3.28Å; P94-R205 VanDerWaalsContact CG-NH2 3.26Å; S200-R205 PolarHBondContact O-N 3.11Å; L203-R205 HydrophobicContact CB-CG 4.16Å; R205-L207 HydrophobicContact CB-CD2 4.26Å; R205-L207 HydrophobicContact CB-CG 4.36Å; R205-L207 PolarHBondContact O-N 2.61Å; R205-L207 VanDerWaalsContact O-N 3.14Å
206D94.3Very high97.6Very high122 Ų12256.8 Ų56.865%0.65228%0.278SS*.  trans44.147.9175.5-60-49.2000113.8S200S200-D206 WeakPolarHBondContact OG-CA 3.46Å; S200-D206 PolarHBondContact OG-N 3.05Å
207L97.4Very high97.4Very high24 Ų2461.9 Ų61.913%0.12631%0.305CS..  trans-54.6144.7178-60.5-174.6000112.7V58 S200 R205 T211 L212V58-L207 HydrophobicContact CB-CD1 4.48Å; V58-L207 HydrophobicContact CG1-CD1 4.27Å; V58-L207 HydrophobicContact CG2-CD1 4.47Å; S200-L207 WeakPolarHBondContact OG-CG 3.36Å; S200-L207 PolarHBondContact OG-N 3.28Å; R205-L207 HydrophobicContact CB-CD2 4.26Å; R205-L207 HydrophobicContact CB-CG 4.36Å; R205-L207 PolarHBondContact O-N 2.61Å; R205-L207 VanDerWaalsContact O-N 3.14Å; L207-T211 HydrophobicContact CB-CG2 4.36Å; L207-T211 HydrophobicContact CD1-CG2 4.08Å; L207-T211 HydrophobicContact CD2-CG2 4.28Å; L207-T211 HydrophobicContact CG-CG2 4.49Å; L207-L212 HydrophobicContact CB-CD2 3.94Å; L207-L212 HydrophobicContact CB-CG 3.92Å; L207-L212 HydrophobicContact CD1-CD2 4.06Å
208S98Very high97.2Very high60 Ų6060.3 Ų60.342%0.4230%0.298SS..  trans-67.6154.9174.967.60000112.2E210 T211 L212S208-E210 VanDerWaalsContact C-N 3.27Å; S208-E210 PolarHBondContact O-N 3Å; S208-T211 WeakPolarHBondContact O-CB 3.44Å; S208-T211 PolarHBondContact O-N 3.3Å; S208-T211 PolarHBondContact OG-N 3.43Å; S208-T211 PolarHBondContact OG-OG1 3.42Å; S208-L212 WeakPolarHBondContact O-CG 3.43Å; S208-L212 PolarHBondContact O-N 2.98Å
209E97.4Very high97.1Very high116 Ų11656.5 Ų56.554%0.54228%0.284SS..Hα-helixtrans-48-48.6173.1-65.1-64.4120.900112.3R193 T211 L212 D213R193-E209 IonicContact CZ-OE2 2.79Å; R193-E209 IonicContact NH2-OE1 3.06Å; R193-E209 PolarHBondContact NH2-OE1 3.25Å; R193-E209 IonicContact NH2-OE2 3.97Å; R193-E209 PolarHBondContact NH2-OE2 3.01Å; E209-T211 VanDerWaalsContact C-N 3.33Å; E209-T211 PolarHBondContact O-N 3.48Å; E209-L212 PolarHBondContact O-N 3.09Å; E209-D213 PolarHBondContact O-N 3.1Å
210E97.5Very high96.8Very high152 Ų15258.1 Ų58.171%0.7130%0.295SS*.Hα-helixtrans-59.8-41.7177.9-175.5-173.4171.600112.5S208 R214S208-E210 VanDerWaalsContact C-N 3.27Å; S208-E210 PolarHBondContact O-N 3Å; E210-R214 WeakPolarHBondContact O-CB 3.31Å; E210-R214 PolarHBondContact O-N 2.83Å
211T97.8Very high96.3Very high19 Ų1960.7 Ų60.712%0.11731%0.306CS..Hα-helixtrans-67.5-43178.3-57.10000110.5G61 L207 S208 E209 D213 R214 V215G61-T211 VanDerWaalsContact O-CG2 3.3Å; G61-T211 WeakPolarHBondContact O-CG2 3.19Å; L207-T211 HydrophobicContact CB-CG2 4.36Å; L207-T211 HydrophobicContact CD1-CG2 4.08Å; L207-T211 HydrophobicContact CD2-CG2 4.28Å; L207-T211 HydrophobicContact CG-CG2 4.49Å; S208-T211 WeakPolarHBondContact O-CB 3.44Å; S208-T211 PolarHBondContact O-N 3.3Å; S208-T211 PolarHBondContact OG-N 3.43Å; S208-T211 PolarHBondContact OG-OG1 3.42Å; E209-T211 VanDerWaalsContact C-N 3.33Å; E209-T211 PolarHBondContact O-N 3.48Å; T211-D213 VanDerWaalsContact C-N 3.34Å; T211-D213 PolarHBondContact O-N 3.23Å; T211-R214 PolarHBondContact O-N 2.9Å; T211-V215 HydrophobicContact CG2-CG2 4.35Å; T211-V215 WeakPolarHBondContact O-CB 3.48Å; T211-V215 VanDerWaalsContact O-CG2 3.29Å; T211-V215 WeakPolarHBondContact O-CG2 3.44Å; T211-V215 PolarHBondContact O-N 2.85Å
212L98.1Very high96Very high2 Ų257.7 Ų57.71%0.0131%0.305CS..Hα-helixtrans-62.4-42178.8-68.5166.9000111.2R193 L196 E197 L207 S208 E209 V215 A216R193-L212 VanDerWaalsContact CZ-CB 3.5Å; R193-L212 VanDerWaalsContact CZ-CD1 3.47Å; R193-L212 VanDerWaalsContact NH2-CD1 3.29Å; L196-L212 HydrophobicContact CB-CD2 3.81Å; E197-L212 HydrophobicContact CB-CD1 4.33Å; E197-L212 HydrophobicContact CG-CD1 4.08Å; L207-L212 HydrophobicContact CB-CD2 3.94Å; L207-L212 HydrophobicContact CB-CG 3.92Å; L207-L212 HydrophobicContact CD1-CD2 4.06Å; S208-L212 WeakPolarHBondContact O-CG 3.43Å; S208-L212 PolarHBondContact O-N 2.98Å; E209-L212 PolarHBondContact O-N 3.09Å; L212-V215 PolarHBondContact O-N 3.37Å; L212-A216 VanDerWaalsContact O-CB 3.28Å; L212-A216 WeakPolarHBondContact O-CB 3.37Å; L212-A216 PolarHBondContact O-N 2.86Å
213D97.3Very high95.7Very high88 Ų8858.8 Ų58.847%0.47131%0.313SS..Hα-helixtrans-65.8-42.5176.6-69-14.7000111.9R193 E209 T211 A216 N217R193-D213 VanDerWaalsContact CD-OD1 3.26Å; R193-D213 WeakPolarHBondContact CD-OD1 3.47Å; R193-D213 IonicContact NE-OD1 2.86Å; R193-D213 PolarHBondContact NE-OD1 3.39Å; E209-D213 PolarHBondContact O-N 3.1Å; T211-D213 VanDerWaalsContact C-N 3.34Å; T211-D213 PolarHBondContact O-N 3.23Å; D213-A216 PolarHBondContact O-N 3.06Å; D213-N217 WeakPolarHBondContact O-CB 3.49Å; D213-N217 PolarHBondContact O-N 2.83Å
214R96.8Very high95.4Very high115 Ų11558.4 Ų58.443%0.43431%0.311SS..Hα-helixtrans-61.1-46.3175.7-176.6175.668.2-165.8-1.1111.6G61 G62 E210 T211 N217 H218G61-R214 PolarHBondContact O-NH2 3.37Å; G62-R214 PolarHBondContact O-NH2 3.1Å; E210-R214 WeakPolarHBondContact O-CB 3.31Å; E210-R214 PolarHBondContact O-N 2.83Å; T211-R214 PolarHBondContact O-N 2.9Å; R214-N217 PolarHBondContact O-N 3.28Å; R214-H218 PolarHBondContact O-N 3.13Å
215V97.6Very high95.2Very high1 Ų160.2 Ų60.21%0.00631%0.305CS..Hα-helixtrans-65.9-42.4177.8172.80000110.6L57 L196 T211 L212 N217 H218 C219L57-V215 HydrophobicContact CB-CG1 4Å; L57-V215 HydrophobicContact CB-CG2 4.06Å; L57-V215 HydrophobicContact CD1-CG1 3.98Å; L57-V215 HydrophobicContact CD1-CG2 4.46Å; L196-V215 HydrophobicContact CD1-CB 4.22Å; L196-V215 HydrophobicContact CD1-CG1 3.86Å; L196-V215 HydrophobicContact CD2-CG1 3.74Å; L196-V215 HydrophobicContact CG-CG1 4.48Å; T211-V215 HydrophobicContact CG2-CG2 4.35Å; T211-V215 WeakPolarHBondContact O-CB 3.48Å; T211-V215 VanDerWaalsContact O-CG2 3.29Å; T211-V215 WeakPolarHBondContact O-CG2 3.44Å; T211-V215 PolarHBondContact O-N 2.85Å; L212-V215 PolarHBondContact O-N 3.37Å; V215-N217 VanDerWaalsContact C-N 3.32Å; V215-N217 PolarHBondContact O-N 3.19Å; V215-H218 PolarHBondContact O-N 3.43Å; V215-C219 VanDerWaalsContact O-CB 3.28Å; V215-C219 WeakPolarHBondContact O-CB 3.26Å; V215-C219 PolarHBondContact O-N 3.31Å; V215-C219 PolarHBondContact O-SG 2.99Å
216A96.7Very high95Very high16 Ų1662.1 Ų62.113%0.13232%0.322CS..Hα-helixtrans-58.7-44.5176.500000111.7L192 R193 L196 L212 D213 C219 C220L192-A216 HydrophobicContact CD2-CB 4.32Å; L192-A216 WeakPolarHBondContact CD2-O 3.35Å; R193-A216 HydrophobicContact CB-CB 4.36Å; L196-A216 HydrophobicContact CD1-CB 3.69Å; L212-A216 VanDerWaalsContact O-CB 3.28Å; L212-A216 WeakPolarHBondContact O-CB 3.37Å; L212-A216 PolarHBondContact O-N 2.86Å; D213-A216 PolarHBondContact O-N 3.06Å; A216-C219 PolarHBondContact O-N 2.94Å; A216-C220 PolarHBondContact O-N 3.27Å
217N95.1Very high95Very high109 Ų10957.3 Ų57.358%0.58330%0.296SS*.Hα-helixtrans-64.3-46.2177.1-174.439.8000111.7D213 R214 V215 C219 C220 N223D213-N217 WeakPolarHBondContact O-CB 3.49Å; D213-N217 PolarHBondContact O-N 2.83Å; R214-N217 PolarHBondContact O-N 3.28Å; V215-N217 VanDerWaalsContact C-N 3.32Å; V215-N217 PolarHBondContact O-N 3.19Å; N217-C219 PolarHBondContact O-N 3.46Å; N217-C220 PolarHBondContact O-N 2.99Å; N217-C220 PolarHBondContact O-SG 2.9Å; N217-N223 PolarHBondContact O-ND2 3.46Å
218H94.9Very high94.9Very high25 Ų2557.7 Ų57.712%0.11630%0.303CS..Hα-helixtrans-62.1-43.4177.7-179.482.5000112.2E53 L64 R214 V215 C220 N223E53-H218 IonicContact OE1-CD2 2.6Å; E53-H218 IonicContact OE1-CE1 3.66Å; E53-H218 IonicContact OE1-NE2 3.92Å; E53-H218 PolarHBondContact OE1-NE2 3.08Å; L64-H218 HydrophobicContact CD2-CB 3.96Å; R214-H218 PolarHBondContact O-N 3.13Å; V215-H218 PolarHBondContact O-N 3.43Å; H218-C220 PolarHBondContact O-N 3.41Å; H218-N223 VanDerWaalsContact O-CB 3.28Å; H218-N223 WeakPolarHBondContact O-CB 3.32Å
219C95.1Very high94.9Very high0 Ų056.6 Ų56.60%029%0.292CS..THydrogen-bonded Turntrans-79.23.8-177.3-69.40000114W50 I54 L192 V215 A216 N217W50-C219 PolarHBondContact NE1-O 2.83Å; I54-C219 HydrophobicContact CG1-CB 4.04Å; L192-C219 HydrophobicContact CD2-CB 3.95Å; V215-C219 VanDerWaalsContact O-CB 3.28Å; V215-C219 WeakPolarHBondContact O-CB 3.26Å; V215-C219 PolarHBondContact O-N 3.31Å; V215-C219 PolarHBondContact O-SG 2.99Å; A216-C219 PolarHBondContact O-N 2.94Å; N217-C219 PolarHBondContact O-N 3.46Å
220C91.9Very high94.7Very high35 Ų3551 Ų5124%0.23627%0.266CS..SBendtrans-67.4150.3173.876.30000111A216 N217 H218 S222 N223 M224A216-C220 PolarHBondContact O-N 3.27Å; N217-C220 PolarHBondContact O-N 2.99Å; N217-C220 PolarHBondContact O-SG 2.9Å; H218-C220 PolarHBondContact O-N 3.41Å; C220-S222 VanDerWaalsContact C-N 3.28Å; C220-S222 PolarHBondContact O-N 3.48Å; C220-S222 PolarHBondContact SG-OG 2.94Å; C220-N223 PolarHBondContact O-N 2.89Å; C220-N223 PolarHBondContact SG-ND2 3.43Å; C220-M224 PolarHBondContact O-N 2.92Å
221F89.1Confident94.5Very high56 Ų5645.2 Ų45.225%0.24624%0.24CC..Hα-helixtrans-55.5-40.6-173.2177.7-100.5000113.4N223 K225 L248 K250 G251F221-N223 VanDerWaalsContact C-N 3.3Å; F221-N223 PolarHBondContact O-N 2.89Å; F221-K225 HydrophobicContact CE1-CD 4.08Å; F221-K225 HydrophobicContact CZ-CD 4.23Å; F221-K225 VanDerWaalsContact O-CB 3.3Å; F221-K225 WeakPolarHBondContact O-CB 3.49Å; F221-K225 PolarHBondContact O-N 3.4Å; F221-L248 HydrophobicContact CE2-CB 3.78Å; F221-L248 HydrophobicContact CE2-CD2 4.38Å; F221-L248 HydrophobicContact CZ-CB 4.11Å; F221-K250 WeakPolarHBondContact CE1-O 3.42Å; F221-G251 VanDerWaalsContact CD2-CA 3.42Å; F221-G251 VanDerWaalsContact CE2-CA 3.41Å
222S90.2Very high94.3Very high72 Ų7245.7 Ų45.750%0.50324%0.239SC..Hα-helixtrans-61.8-37.7179.2470000112.5C220 L226C220-S222 VanDerWaalsContact C-N 3.28Å; C220-S222 PolarHBondContact O-N 3.48Å; C220-S222 PolarHBondContact SG-OG 2.94Å; S222-L226 WeakPolarHBondContact O-CG 3.34Å
223N92.1Very high94.1Very high57 Ų5749.3 Ų49.331%0.30527%0.265SS..Hα-helixtrans-78.9-44.8-178.8-71-9.1000111.2N217 H218 C220 F221 K225 L226 N227N217-N223 PolarHBondContact O-ND2 3.46Å; H218-N223 VanDerWaalsContact O-CB 3.28Å; H218-N223 WeakPolarHBondContact O-CB 3.32Å; C220-N223 PolarHBondContact O-N 2.89Å; C220-N223 PolarHBondContact SG-ND2 3.43Å; F221-N223 VanDerWaalsContact C-N 3.3Å; F221-N223 PolarHBondContact O-N 2.89Å; N223-K225 PolarHBondContact O-N 2.84Å; N223-L226 PolarHBondContact O-N 2.76Å; N223-N227 PolarHBondContact O-N 2.75Å
224M93.3Very high93.9Very high6 Ų649.2 Ų49.23%0.0326%0.264CS..Hα-helixtrans-58.2-35.9174.8-73.5-167.764.500112.6T49 W50 E53 C220 L226 N227 L248T49-M224 HydrophobicContact CG2-CE 4.15Å; W50-M224 HydrophobicContact CG-SD 4.24Å; E53-M224 HydrophobicContact CB-CE 3.54Å; E53-M224 HydrophobicContact CB-SD 3.92Å; E53-M224 HydrophobicContact CG-CE 3.94Å; E53-M224 HydrophobicContact CG-CG 4.21Å; E53-M224 HydrophobicContact CG-SD 4.05Å; C220-M224 PolarHBondContact O-N 2.92Å; M224-L226 PolarHBondContact O-N 3.22Å; M224-N227 PolarHBondContact O-N 3.21Å; M224-N227 VanDerWaalsContact O-N 3.11Å; M224-L248 HydrophobicContact CB-CD1 4.12Å
225K91.8Very high93.8Very high87 Ų8745.1 Ų45.138%0.37825%0.251SS..THydrogen-bonded Turntrans-61.1-26.5177.1-169.8169.9-179.1173.60113.3F221 N223 N231 L248F221-K225 HydrophobicContact CE1-CD 4.08Å; F221-K225 HydrophobicContact CZ-CD 4.23Å; F221-K225 VanDerWaalsContact O-CB 3.3Å; F221-K225 WeakPolarHBondContact O-CB 3.49Å; F221-K225 PolarHBondContact O-N 3.4Å; N223-K225 PolarHBondContact O-N 2.84Å; K225-N231 PolarHBondContact O-ND2 2.78Å; K225-L248 HydrophobicContact CB-CD1 4.35Å; K225-L248 HydrophobicContact CG-CB 4.38Å
226L92.7Very high93.7Very high142 Ų14248.2 Ų48.274%0.74327%0.272SS*.THydrogen-bonded Turntrans-89.3-15.2178.1-59.3174.4000113S222 N223 M224 A228S222-L226 WeakPolarHBondContact O-CG 3.34Å; N223-L226 PolarHBondContact O-N 2.76Å; M224-L226 PolarHBondContact O-N 3.22Å; L226-A228 PolarHBondContact O-N 3.49Å
227N94.6Very high93.5Very high22 Ų2252.5 Ų52.512%0.11829%0.289CS..  trans-82.9107.9-179.1-174.46.3000111.3E53 V67 N223 M224 M229 S230 N231E53-N227 PolarHBondContact OE1-ND2 3.06Å; V67-N227 PolarHBondContact O-ND2 3.36Å; N223-N227 PolarHBondContact O-N 2.75Å; M224-N227 PolarHBondContact O-N 3.21Å; M224-N227 VanDerWaalsContact O-N 3.11Å; N227-M229 PolarHBondContact O-N 3.47Å; N227-M229 VanDerWaalsContact O-N 3.13Å; N227-M229 WeakPolarHBondContact OD1-CB 3.39Å; N227-M229 PolarHBondContact OD1-N 3.03Å; N227-M229 VanDerWaalsContact OD1-N 3.11Å; N227-S230 PolarHBondContact ND2-OG 2.95Å; N227-S230 PolarHBondContact O-N 2.75Å; N227-N231 WeakPolarHBondContact O-CB 3.07Å; N227-N231 PolarHBondContact O-N 3.45Å; N227-N231 PolarHBondContact O-OD1 2.91Å
228A95.8Very high93.4Very high32 Ų3254.4 Ų54.426%0.26429%0.294SS..THydrogen-bonded Turntrans-57.4-26.617800000113.5L226 S230 N231 L234L226-A228 PolarHBondContact O-N 3.49Å; A228-S230 PolarHBondContact O-N 3.12Å; A228-N231 WeakPolarHBondContact CA-OD1 3.3Å; A228-L234 HydrophobicContact CB-CD2 4.44Å; A228-L234 HydrophobicContact CB-CG 4.48Å; A228-L234 WeakPolarHBondContact O-CG 3.4Å
229M97.2Very high93.3Very high36 Ų3655.4 Ų55.418%0.17730%0.3CS..THydrogen-bonded Turntrans-75.7-10178.2-61.5-57.4139.900113.7V67 Q68 P71 N72 N227 L234V67-M229 VanDerWaalsContact O-CB 3.31Å; V67-M229 WeakPolarHBondContact O-CB 3.28Å; Q68-M229 WeakPolarHBondContact O-CG 3.23Å; P71-M229 CarbonylContact C-O 3.55Å; P71-M229 WeakPolarHBondContact CA-O 3.33Å; P71-M229 HydrophobicContact CG-SD 3.89Å; N72-M229 PolarHBondContact N-O 2.62Å; N72-M229 PolarHBondContact OD1-O 2.91Å; N227-M229 PolarHBondContact O-N 3.47Å; N227-M229 VanDerWaalsContact O-N 3.13Å; N227-M229 WeakPolarHBondContact OD1-CB 3.39Å; N227-M229 PolarHBondContact OD1-N 3.03Å; N227-M229 VanDerWaalsContact OD1-N 3.11Å; M229-L234 HydrophobicContact CE-CD1 3.77Å; M229-L234 HydrophobicContact SD-CD1 3.73Å
230S93.9Very high93.3Very high0 Ų056.1 Ų56.10%030%0.303CS..THydrogen-bonded Turntrans-134.4-15.8-173.7-51.90000113.7T49 E53 N227 A228T49-S230 VanDerWaalsContact CG2-O 3.26Å; T49-S230 WeakPolarHBondContact CG2-O 3.34Å; E53-S230 VanDerWaalsContact CD-OG 3.3Å; E53-S230 PolarHBondContact OE1-OG 3.43Å; E53-S230 PolarHBondContact OE2-OG 3.13Å; N227-S230 PolarHBondContact ND2-OG 2.95Å; N227-S230 PolarHBondContact O-N 2.75Å; A228-S230 PolarHBondContact O-N 3.12Å
231N92.6Very high93.4Very high30 Ų3056 Ų5616%0.1630%0.3CS..SBendtrans-92.1-0.2-177.973.85.5000114.5K225 N227 A228 S233 L248K225-N231 PolarHBondContact O-ND2 2.78Å; N227-N231 WeakPolarHBondContact O-CB 3.07Å; N227-N231 PolarHBondContact O-N 3.45Å; N227-N231 PolarHBondContact O-OD1 2.91Å; A228-N231 WeakPolarHBondContact CA-OD1 3.3Å; N231-S233 VanDerWaalsContact C-N 3.31Å; N231-S233 PolarHBondContact O-N 2.81Å; N231-S233 VanDerWaalsContact OD1-CB 3.26Å; N231-S233 WeakPolarHBondContact OD1-CB 3.45Å; N231-S233 PolarHBondContact OD1-N 2.68Å; N231-S233 PolarHBondContact OD1-OG 3.31Å; N231-L248 HydrophobicContact CB-CD1 3.91Å
232Y94.1Very high93.4Very high28 Ų2856.8 Ų56.811%0.1131%0.313CS..SBendtrans68.614.9-178.9-68.5-109.8000115.8T49 N72 W73 W78 L234 V235 M240 F247T49-Y232 HydrophobicContact CG2-CE2 3.94Å; N72-Y232 WeakPolarHBondContact ND2-CE2 3.3Å; N72-Y232 PolarHBondContact ND2-OH 2.6Å; W73-Y232 HydrophobicContact CE3-CD1 4.1Å; W73-Y232 AromaticContact CE3-CE1 3.79Å; W73-Y232 HydrophobicContact CE3-CE1 3.79Å; W73-Y232 AromaticContact CZ3-CD1 3.58Å; W73-Y232 HydrophobicContact CZ3-CD1 3.58Å; W73-Y232 AromaticContact CZ3-CE1 3.77Å; W73-Y232 HydrophobicContact CZ3-CE1 3.77Å; W73-Y232 AromaticContact CZ3-CG 3.99Å; W73-Y232 HydrophobicContact CZ3-CG 3.99Å; W78-Y232 WeakPolarHBondContact CH2-OH 3.42Å; Y232-L234 PolarHBondContact O-N 2.98Å; Y232-V235 HydrophobicContact CD1-CG2 3.88Å; Y232-V235 WeakPolarHBondContact O-CB 3.31Å; Y232-V235 PolarHBondContact O-N 2.97Å; Y232-V235 VanDerWaalsContact O-N 3.12Å; Y232-M240 HydrophobicContact CD1-CE 4.08Å; Y232-M240 HydrophobicContact CD1-SD 3.99Å; Y232-M240 HydrophobicContact CG-CE 4.22Å; Y232-F247 HydrophobicContact CD1-CD2 4.44Å; Y232-F247 HydrophobicContact CD1-CE2 4.39Å; Y232-F247 HydrophobicContact CD2-CB 4.41Å; Y232-F247 AromaticContact CD2-CD1 3.34Å; Y232-F247 HydrophobicContact CD2-CD1 3.34Å; Y232-F247 HydrophobicContact CD2-CD2 4.21Å; Y232-F247 AromaticContact CD2-CE1 3.47Å; Y232-F247 HydrophobicContact CD2-CE1 3.47Å; Y232-F247 VanDerWaalsContact CD2-CE1 3.47Å; Y232-F247 HydrophobicContact CD2-CE2 4.26Å; Y232-F247 AromaticContact CD2-CG 3.73Å; Y232-F247 HydrophobicContact CD2-CG 3.73Å; Y232-F247 AromaticContact CD2-CZ 3.91Å; Y232-F247 HydrophobicContact CD2-CZ 3.91Å; Y232-F247 HydrophobicContact CE1-CE2 4.23Å; Y232-F247 HydrophobicContact CE1-CZ 4.23Å; Y232-F247 AromaticContact CE2-CD1 3.65Å; Y232-F247 HydrophobicContact CE2-CD1 3.65Å; Y232-F247 AromaticContact CE2-CE1 3.2Å; Y232-F247 HydrophobicContact CE2-CE1 3.2Å; Y232-F247 HydrophobicContact CE2-CE2 4.1Å; Y232-F247 HydrophobicContact CE2-CG 4.27Å; Y232-F247 AromaticContact CE2-CZ 3.43Å; Y232-F247 HydrophobicContact CE2-CZ 3.43Å; Y232-F247 VanDerWaalsContact CE2-CZ 3.43Å; Y232-F247 HydrophobicContact CG-CB 4.39Å; Y232-F247 HydrophobicContact CG-CD1 4.05Å; Y232-F247 HydrophobicContact CG-CD2 4.17Å; Y232-F247 HydrophobicContact CG-CE1 4.34Å; Y232-F247 HydrophobicContact CG-CE2 4.4Å; Y232-F247 AromaticContact CG-CG 3.94Å; Y232-F247 HydrophobicContact CG-CG 3.94Å; Y232-F247 HydrophobicContact CG-CZ 4.48Å; Y232-F247 AromaticContact CZ-CE1 3.9Å; Y232-F247 AromaticContact CZ-CZ 3.59Å
233S92.6Very high93.4Very high78 Ų7857.7 Ų57.755%0.54532%0.319SS..THydrogen-bonded Turntrans-68.8-12.5175.8700000113.9N231 V235N231-S233 VanDerWaalsContact C-N 3.31Å; N231-S233 PolarHBondContact O-N 2.81Å; N231-S233 VanDerWaalsContact OD1-CB 3.26Å; N231-S233 WeakPolarHBondContact OD1-CB 3.45Å; N231-S233 PolarHBondContact OD1-N 2.68Å; N231-S233 PolarHBondContact OD1-OG 3.31Å; S233-V235 VanDerWaalsContact C-N 3.33Å
234L94.7Very high93.2Very high86 Ų8661.5 Ų61.545%0.4533%0.333SS..THydrogen-bonded Turntrans-81.7-12.2173.9-59175.8000112.9P71 W73 A228 M229 Y232P71-L234 HydrophobicContact CG-CD1 4.13Å; W73-L234 HydrophobicContact CH2-CB 4.1Å; W73-L234 HydrophobicContact CZ2-CB 4.28Å; A228-L234 HydrophobicContact CB-CD2 4.44Å; A228-L234 HydrophobicContact CB-CG 4.48Å; A228-L234 WeakPolarHBondContact O-CG 3.4Å; M229-L234 HydrophobicContact CE-CD1 3.77Å; M229-L234 HydrophobicContact SD-CD1 3.73Å; Y232-L234 PolarHBondContact O-N 2.98Å
235V93.8Very high93Very high29 Ų2961.8 Ų61.818%0.17634%0.336CS..SBendtrans-76.2132.7174.2-179.20000108.7W73 Y232 S233 I239 M240W73-V235 HydrophobicContact CH2-CG2 3.7Å; W73-V235 HydrophobicContact CZ2-CG2 4.45Å; W73-V235 HydrophobicContact CZ3-CG2 3.92Å; Y232-V235 HydrophobicContact CD1-CG2 3.88Å; Y232-V235 WeakPolarHBondContact O-CB 3.31Å; Y232-V235 PolarHBondContact O-N 2.97Å; Y232-V235 VanDerWaalsContact O-N 3.12Å; S233-V235 VanDerWaalsContact C-N 3.33Å; V235-I239 HydrophobicContact CG1-CB 3.84Å; V235-I239 HydrophobicContact CG1-CG2 3.75Å; V235-M240 HydrophobicContact CB-CB 4.42Å; V235-M240 HydrophobicContact CB-SD 4.21Å; V235-M240 HydrophobicContact CG1-CB 3.94Å; V235-M240 HydrophobicContact CG1-CG 3.92Å; V235-M240 HydrophobicContact CG1-SD 3.9Å; V235-M240 HydrophobicContact CG2-SD 4.22Å
236P95.4Very high92.9Very high66 Ų6660.5 Ų60.543%0.42934%0.336SS..  trans-52141.5176.8-27.133.8000112.8E238 I239 M240P236-E238 VanDerWaalsContact CB-OE2 3.32Å; P236-E238 WeakPolarHBondContact CB-OE2 3.39Å; P236-E238 PolarHBondContact O-N 3.41Å; P236-I239 HydrophobicContact CB-CD1 4.3Å; P236-I239 HydrophobicContact CB-CG1 4.28Å; P236-I239 HydrophobicContact CG-CD1 4.07Å; P236-I239 WeakPolarHBondContact O-CB 3.39Å; P236-I239 PolarHBondContact O-N 3.2Å; P236-M240 PolarHBondContact O-N 3.22Å
237Q92.4Very high92.7Very high107 Ų10755.6 Ų55.650%0.531%0.308SS..THydrogen-bonded Turntrans-64-27.1-176.8-171.8174.7-3.600112.2I239 M240 D241Q237-I239 PolarHBondContact O-N 3.47Å; Q237-M240 CarbonylContact O-C 3.52Å; Q237-M240 VanDerWaalsContact O-C 3.31Å; Q237-D241 PolarHBondContact NE2-OD1 2.86Å; Q237-D241 WeakPolarHBondContact O-CA 3.14Å; Q237-D241 PolarHBondContact O-N 2.97Å
238E93.4Very high92.5Very high149 Ų14955.7 Ų55.770%0.69631%0.309SS*.THydrogen-bonded Turntrans-67.5-25.4175.6-56.475.4-163.800112.2S139 P236S139-E238 VanDerWaalsContact CB-O 3.25Å; S139-E238 WeakPolarHBondContact CB-O 3.25Å; S139-E238 PolarHBondContact OG-O 2.89Å; P236-E238 VanDerWaalsContact CB-OE2 3.32Å; P236-E238 WeakPolarHBondContact CB-OE2 3.39Å; P236-E238 PolarHBondContact O-N 3.41Å
239I93.4Very high92.2Very high45 Ų4556.3 Ų56.323%0.23130%0.304CS..THydrogen-bonded Turntrans-90.4-45.2176.7-61.3-179.8000109.8A138 S139 F140 V235 P236 Q237A138-I239 WeakPolarHBondContact CA-O 3.49Å; S139-I239 PolarHBondContact N-O 3.39Å; S139-I239 WeakPolarHBondContact OG-CA 3.26Å; S139-I239 PolarHBondContact OG-O 3.41Å; F140-I239 HydrophobicContact CD1-CG2 3.69Å; F140-I239 HydrophobicContact CE1-CG2 3.71Å; V235-I239 HydrophobicContact CG1-CB 3.84Å; V235-I239 HydrophobicContact CG1-CG2 3.75Å; P236-I239 HydrophobicContact CB-CD1 4.3Å; P236-I239 HydrophobicContact CB-CG1 4.28Å; P236-I239 HydrophobicContact CG-CD1 4.07Å; P236-I239 WeakPolarHBondContact O-CB 3.39Å; P236-I239 PolarHBondContact O-N 3.2Å; Q237-I239 PolarHBondContact O-N 3.47Å
240M94.5Very high91.8Very high15 Ų1559 Ų597%0.07432%0.315CS..BIsolated β-bridgetrans-132.799.1-179.2-77.1-178.561.900111.6F134 M137 F140 Y232 V235 P236 Q237 S242 F247F134-M240 HydrophobicContact CE2-CE 4.1Å; M137-M240 HydrophobicContact CE-CB 3.99Å; M137-M240 HydrophobicContact CE-CE 3.69Å; M137-M240 HydrophobicContact CE-CG 4.5Å; M137-M240 HydrophobicContact SD-CE 4.41Å; F140-M240 HydrophobicContact CE1-CG 4.24Å; Y232-M240 HydrophobicContact CD1-CE 4.08Å; Y232-M240 HydrophobicContact CD1-SD 3.99Å; Y232-M240 HydrophobicContact CG-CE 4.22Å; V235-M240 HydrophobicContact CB-CB 4.42Å; V235-M240 HydrophobicContact CB-SD 4.21Å; V235-M240 HydrophobicContact CG1-CB 3.94Å; V235-M240 HydrophobicContact CG1-CG 3.92Å; V235-M240 HydrophobicContact CG1-SD 3.9Å; V235-M240 HydrophobicContact CG2-SD 4.22Å; P236-M240 PolarHBondContact O-N 3.22Å; Q237-M240 CarbonylContact O-C 3.52Å; Q237-M240 VanDerWaalsContact O-C 3.31Å; M240-S242 PolarHBondContact O-N 3Å; M240-F247 HydrophobicContact CE-CB 3.9Å; M240-F247 HydrophobicContact CE-CD2 3.36Å; M240-F247 HydrophobicContact CE-CE2 4.19Å; M240-F247 HydrophobicContact CE-CG 3.99Å
241D93.4Very high91.5Very high32 Ų3259.6 Ų59.617%0.17132%0.321CS..  trans-81.492.4-174.6-173.92.5000112M137 Q237 S243 K244 S245M137-D241 PolarHBondContact O-N 3.27Å; Q237-D241 PolarHBondContact NE2-OD1 2.86Å; Q237-D241 WeakPolarHBondContact O-CA 3.14Å; Q237-D241 PolarHBondContact O-N 2.97Å; D241-S243 VanDerWaalsContact CG-OG 3.25Å; D241-S243 PolarHBondContact O-N 2.96Å; D241-S243 VanDerWaalsContact O-N 3.09Å; D241-S243 VanDerWaalsContact OD1-CB 3.28Å; D241-S243 WeakPolarHBondContact OD1-CB 3.32Å; D241-S243 PolarHBondContact OD1-N 3.05Å; D241-S243 PolarHBondContact OD1-OG 3.12Å; D241-S243 PolarHBondContact OD2-OG 3.19Å; D241-K244 HydrophobicContact CB-CD 4.31Å; D241-K244 HydrophobicContact CB-CG 4.44Å; D241-K244 PolarHBondContact O-N 2.78Å; D241-K244 VanDerWaalsContact O-N 3.08Å; D241-K244 WeakPolarHBondContact OD2-CE 3.48Å; D241-K244 WeakPolarHBondContact OD2-CG 3.44Å; D241-S245 PolarHBondContact O-N 2.79Å
242S89.4Confident91.5Very high73 Ų7361.1 Ų61.151%0.5133%0.332SS..THydrogen-bonded Turntrans-60.4-16.8178.966.80000114.5M240 K244 S245M240-S242 PolarHBondContact O-N 3Å; S242-K244 VanDerWaalsContact C-N 3.34Å; S242-S245 WeakPolarHBondContact CA-O 3.45Å; S242-S245 CarbonylContact O-C 3.58Å
243S89.8Confident91.6Very high91 Ų9161.8 Ų61.864%0.63634%0.343SS*.THydrogen-bonded Turntrans-72.7-26.9176.178.50000112.9D241D241-S243 VanDerWaalsContact CG-OG 3.25Å; D241-S243 PolarHBondContact O-N 2.96Å; D241-S243 VanDerWaalsContact O-N 3.09Å; D241-S243 VanDerWaalsContact OD1-CB 3.28Å; D241-S243 WeakPolarHBondContact OD1-CB 3.32Å; D241-S243 PolarHBondContact OD1-N 3.05Å; D241-S243 PolarHBondContact OD1-OG 3.12Å; D241-S243 PolarHBondContact OD2-OG 3.19Å
244K88.6Confident91.8Very high137 Ų13758.8 Ų58.860%0.59632%0.324SS*.THydrogen-bonded Turntrans-84.8-42.1175.9-66.3179-175.1174.60112K136 M137 D241 S242K136-K244 WeakPolarHBondContact O-CD 3.48Å; M137-K244 HydrophobicContact CB-CB 4.43Å; D241-K244 HydrophobicContact CB-CD 4.31Å; D241-K244 HydrophobicContact CB-CG 4.44Å; D241-K244 PolarHBondContact O-N 2.78Å; D241-K244 VanDerWaalsContact O-N 3.08Å; D241-K244 WeakPolarHBondContact OD2-CE 3.48Å; D241-K244 WeakPolarHBondContact OD2-CG 3.44Å; S242-K244 VanDerWaalsContact C-N 3.34Å
245S89.8Confident91.9Very high13 Ų1354.9 Ų54.99%0.09130%0.304CS..  trans-160.1144.2174.3-152.30000109.9M137 D241 S242M137-S245 WeakPolarHBondContact CE-O 3.46Å; D241-S245 PolarHBondContact O-N 2.79Å; S242-S245 WeakPolarHBondContact CA-O 3.45Å; S242-S245 CarbonylContact O-C 3.58Å
246T89.1Confident92Very high60 Ų6054.4 Ų54.437%0.36830%0.299SS..  trans-84.3145.4169.559.70000110.3L248 R249T246-L248 PolarHBondContact O-N 3.27Å; T246-L248 PolarHBondContact OG1-O 3.34Å; T246-L248 VanDerWaalsContact OG1-O 3.06Å; T246-R249 PolarHBondContact O-N 3.4Å
247F88.8Confident92.1Very high39 Ų3956.8 Ų56.817%0.17130%0.303CS..SBendtrans-59.8-50179.1-174.7-91.5000111.7T49 F134 Y232 M240 R249T49-F247 HydrophobicContact CG2-CE1 4.23Å; T49-F247 VanDerWaalsContact OG1-CE1 3.32Å; T49-F247 WeakPolarHBondContact OG1-CE1 3.4Å; F134-F247 HydrophobicContact CD2-CD2 4.21Å; F134-F247 HydrophobicContact CD2-CE2 4.36Å; F134-F247 AromaticContact CE2-CD2 3.93Å; F134-F247 HydrophobicContact CE2-CD2 3.93Å; F134-F247 AromaticContact CE2-CE2 3.88Å; F134-F247 HydrophobicContact CE2-CE2 3.88Å; F134-F247 HydrophobicContact CZ-CE2 4.48Å; Y232-F247 HydrophobicContact CD1-CD2 4.44Å; Y232-F247 HydrophobicContact CD1-CE2 4.39Å; Y232-F247 HydrophobicContact CD2-CB 4.41Å; Y232-F247 AromaticContact CD2-CD1 3.34Å; Y232-F247 HydrophobicContact CD2-CD1 3.34Å; Y232-F247 HydrophobicContact CD2-CD2 4.21Å; Y232-F247 AromaticContact CD2-CE1 3.47Å; Y232-F247 HydrophobicContact CD2-CE1 3.47Å; Y232-F247 VanDerWaalsContact CD2-CE1 3.47Å; Y232-F247 HydrophobicContact CD2-CE2 4.26Å; Y232-F247 AromaticContact CD2-CG 3.73Å; Y232-F247 HydrophobicContact CD2-CG 3.73Å; Y232-F247 AromaticContact CD2-CZ 3.91Å; Y232-F247 HydrophobicContact CD2-CZ 3.91Å; Y232-F247 HydrophobicContact CE1-CE2 4.23Å; Y232-F247 HydrophobicContact CE1-CZ 4.23Å; Y232-F247 AromaticContact CE2-CD1 3.65Å; Y232-F247 HydrophobicContact CE2-CD1 3.65Å; Y232-F247 AromaticContact CE2-CE1 3.2Å; Y232-F247 HydrophobicContact CE2-CE1 3.2Å; Y232-F247 HydrophobicContact CE2-CE2 4.1Å; Y232-F247 HydrophobicContact CE2-CG 4.27Å; Y232-F247 AromaticContact CE2-CZ 3.43Å; Y232-F247 HydrophobicContact CE2-CZ 3.43Å; Y232-F247 VanDerWaalsContact CE2-CZ 3.43Å; Y232-F247 HydrophobicContact CG-CB 4.39Å; Y232-F247 HydrophobicContact CG-CD1 4.05Å; Y232-F247 HydrophobicContact CG-CD2 4.17Å; Y232-F247 HydrophobicContact CG-CE1 4.34Å; Y232-F247 HydrophobicContact CG-CE2 4.4Å; Y232-F247 AromaticContact CG-CG 3.94Å; Y232-F247 HydrophobicContact CG-CG 3.94Å; Y232-F247 HydrophobicContact CG-CZ 4.48Å; Y232-F247 AromaticContact CZ-CE1 3.9Å; Y232-F247 AromaticContact CZ-CZ 3.59Å; M240-F247 HydrophobicContact CE-CB 3.9Å; M240-F247 HydrophobicContact CE-CD2 3.36Å; M240-F247 HydrophobicContact CE-CE2 4.19Å; M240-F247 HydrophobicContact CE-CG 3.99Å; F247-R249 VanDerWaalsContact C-N 3.35Å; F247-R249 PolarHBondContact O-N 3.42Å; F247-R249 VanDerWaalsContact O-N 3.13Å
248L89Confident92.4Very high24 Ų2457.4 Ų57.413%0.12631%0.309CS..SBendtrans-82.982.1166.7-63.3-177.7000109.1F221 M224 K225 N231 T246F221-L248 HydrophobicContact CE2-CB 3.78Å; F221-L248 HydrophobicContact CE2-CD2 4.38Å; F221-L248 HydrophobicContact CZ-CB 4.11Å; M224-L248 HydrophobicContact CB-CD1 4.12Å; K225-L248 HydrophobicContact CB-CD1 4.35Å; K225-L248 HydrophobicContact CG-CB 4.38Å; N231-L248 HydrophobicContact CB-CD1 3.91Å; T246-L248 PolarHBondContact O-N 3.27Å; T246-L248 PolarHBondContact OG1-O 3.34Å; T246-L248 VanDerWaalsContact OG1-O 3.06Å
249R90.2Very high92.6Very high44 Ų4453 Ų5317%0.16629%0.289CS..  trans-72.7-73.1-171.7-169-177.162.186.93.9113.5T246 F247 D255T246-R249 PolarHBondContact O-N 3.4Å; F247-R249 VanDerWaalsContact C-N 3.35Å; F247-R249 PolarHBondContact O-N 3.42Å; F247-R249 VanDerWaalsContact O-N 3.13Å; R249-D255 IonicContact CZ-OD2 2.72Å; R249-D255 IonicContact NH1-OD2 3.48Å; R249-D255 PolarHBondContact NH1-OD2 3.44Å; R249-D255 IonicContact NH2-OD2 2.75Å; R249-D255 PolarHBondContact NH2-OD2 2.87Å
250K88.6Confident92.8Very high92 Ų9251.9 Ų51.940%0.428%0.282SS..  trans-122.2-33.6-177.5-72.3-166.9-175.7-179.70114.8F221 V252 D255F221-K250 WeakPolarHBondContact CE1-O 3.42Å; K250-V252 VanDerWaalsContact C-N 3.32Å; K250-V252 HydrophobicContact CB-CG2 4.1Å; K250-V252 PolarHBondContact O-N 2.91Å; K250-D255 WeakPolarHBondContact CD-OD1 3.43Å; K250-D255 WeakPolarHBondContact CD-OD2 3.4Å; K250-D255 IonicContact NZ-OD1 2.68Å; K250-D255 PolarHBondContact NZ-OD1 3.44Å; K250-D255 IonicContact NZ-OD2 2.98Å; K250-D255 PolarHBondContact NZ-OD2 3Å
251G88.2Confident92.9Very high14 Ų1453 Ų5314%0.14429%0.291CS..  trans67.726.8177.800000115Y185 I189 F221Y185-G251 VanDerWaalsContact OH-CA 3.3Å; Y185-G251 WeakPolarHBondContact OH-CA 3.31Å; Y185-G251 PolarHBondContact OH-O 2.85Å; I189-G251 WeakPolarHBondContact CD1-O 3.48Å; F221-G251 VanDerWaalsContact CD2-CA 3.42Å; F221-G251 VanDerWaalsContact CE2-CA 3.41Å
252V93.4Very high93.1Very high62 Ų6256.2 Ų56.238%0.37631%0.314SS..  trans-118.9161.8-177.8-57.60000111.9R122 K250 D255R122-V252 PolarHBondContact NH2-O 3.44Å; K250-V252 VanDerWaalsContact C-N 3.32Å; K250-V252 HydrophobicContact CB-CG2 4.1Å; K250-V252 PolarHBondContact O-N 2.91Å; V252-D255 HydrophobicContact CG2-CB 4Å
253A94.9Very high93.6Very high42 Ų4259.2 Ų59.235%0.34732%0.32SS..SBendtrans-93.7145.2164.600000110E186E186-A253 HydrophobicContact CG-CB 4.09Å
254G96.1Very high94Very high15 Ų1556.2 Ų56.216%0.15530%0.296CS..  trans84.513.1176.600000115.5D126 W256 K257D126-G254 PolarHBondContact OD2-N 3.27Å; G254-W256 PolarHBondContact O-N 2.91Å; G254-K257 PolarHBondContact O-N 3.03Å
255D97.1Very high94.4Very high4 Ų451.8 Ų51.82%0.02128%0.279CS..G310 helixtrans-65.2-25.3177.8-167.948.5000111.4D126 R249 K250 V252 K257 N258 H259D126-D255 PolarHBondContact OD1-N 3.16Å; R249-D255 IonicContact CZ-OD2 2.72Å; R249-D255 IonicContact NH1-OD2 3.48Å; R249-D255 PolarHBondContact NH1-OD2 3.44Å; R249-D255 IonicContact NH2-OD2 2.75Å; R249-D255 PolarHBondContact NH2-OD2 2.87Å; K250-D255 WeakPolarHBondContact CD-OD1 3.43Å; K250-D255 WeakPolarHBondContact CD-OD2 3.4Å; K250-D255 IonicContact NZ-OD1 2.68Å; K250-D255 PolarHBondContact NZ-OD1 3.44Å; K250-D255 IonicContact NZ-OD2 2.98Å; K250-D255 PolarHBondContact NZ-OD2 3Å; V252-D255 HydrophobicContact CG2-CB 4Å; D255-K257 PolarHBondContact O-N 3.37Å; D255-K257 VanDerWaalsContact O-N 3.08Å; D255-N258 WeakPolarHBondContact O-CB 3.19Å; D255-N258 PolarHBondContact O-N 3.1Å; D255-N258 PolarHBondContact OD1-ND2 3.26Å; D255-H259 PolarHBondContact O-CD2 3.34Å; D255-H259 IonicContact OD1-NE2 3.98Å; D255-H259 IonicContact OD2-CD2 3.95Å; D255-H259 IonicContact OD2-NE2 3.72Å; D255-H259 PolarHBondContact OD2-NE2 3.37Å
256W97.5Very high94.7Very high18 Ų1858.8 Ų58.87%0.06831%0.308CS..G310 helixtrans-49.5-32.4174.670.6-95.5000114.1K125 D126 V129 G254 N258 H259 F260 D265K125-W256 HydrophobicContact CB-CB 3.6Å; K125-W256 HydrophobicContact CB-CD2 3.86Å; K125-W256 HydrophobicContact CB-CE3 4.36Å; K125-W256 HydrophobicContact CB-CG 3.51Å; K125-W256 HydrophobicContact CD-CD2 3.66Å; K125-W256 HydrophobicContact CD-CE3 3.67Å; K125-W256 HydrophobicContact CD-CG 4.27Å; K125-W256 HydrophobicContact CD-CH2 4.04Å; K125-W256 HydrophobicContact CD-CZ2 4.03Å; K125-W256 HydrophobicContact CD-CZ3 3.87Å; K125-W256 HydrophobicContact CG-CD2 4.39Å; D126-W256 PolarHBondContact OD1-N 2.74Å; V129-W256 HydrophobicContact CG2-CB 4.16Å; G254-W256 PolarHBondContact O-N 2.91Å; W256-N258 PolarHBondContact O-N 3.38Å; W256-N258 VanDerWaalsContact O-N 3.12Å; W256-H259 PolarHBondContact O-N 3.45Å; W256-F260 HydrophobicContact CB-CD2 3.93Å; W256-F260 HydrophobicContact CB-CE2 4Å; W256-F260 HydrophobicContact CE3-CB 4.24Å; W256-F260 HydrophobicContact CE3-CD2 4.39Å; W256-F260 HydrophobicContact CE3-CG 4.25Å; W256-F260 WeakPolarHBondContact O-CD2 3.43Å; W256-F260 PolarHBondContact O-N 3.26Å; W256-D265 HydrophobicContact CZ3-CB 4.4Å; W256-D265 WeakPolarHBondContact CZ3-OD1 3.4Å
257K97Very high95.1Very high117 Ų11760 Ų6051%0.50931%0.308SS..G310 helixtrans-61.4-20.6177.4-61.8177.7-176.2170.50112.9G254 D255 E288G254-K257 PolarHBondContact O-N 3.03Å; D255-K257 PolarHBondContact O-N 3.37Å; D255-K257 VanDerWaalsContact O-N 3.08Å; K257-E288 IonicContact NZ-OE2 3.2Å; K257-E288 PolarHBondContact NZ-OE2 2.68Å
258N97.6Very high95.6Very high120 Ų12058.1 Ų58.164%0.64230%0.3SS*.G310 helixtrans-90.3-6176.9-59.8-50.7000113.9D255 W256D255-N258 WeakPolarHBondContact O-CB 3.19Å; D255-N258 PolarHBondContact O-N 3.1Å; D255-N258 PolarHBondContact OD1-ND2 3.26Å; W256-N258 PolarHBondContact O-N 3.38Å; W256-N258 VanDerWaalsContact O-N 3.12Å
259H97.4Very high95.9Very high57 Ų5759.7 Ų59.726%0.26431%0.311SS..THydrogen-bonded Turntrans-122.2-35.9-174.9-59.7-97.9000113.2V129 H133 F147 D255 W256V129-H259 WeakPolarHBondContact CG1-NE2 3.35Å; V129-H259 HydrophobicContact CG2-CB 4.03Å; H133-H259 AromaticContact NE2-CE1 3.34Å; H133-H259 PolarHBondContact NE2-CE1 3.23Å; H133-H259 VanDerWaalsContact NE2-CE1 3.34Å; H133-H259 AromaticContact NE2-ND1 3.92Å; F147-H259 HydrophobicContact CE1-CB 4.41Å; F147-H259 HydrophobicContact CE2-CB 3.93Å; F147-H259 HydrophobicContact CZ-CB 3.72Å; D255-H259 PolarHBondContact O-CD2 3.34Å; D255-H259 IonicContact OD1-NE2 3.98Å; D255-H259 IonicContact OD2-CD2 3.95Å; D255-H259 IonicContact OD2-NE2 3.72Å; D255-H259 PolarHBondContact OD2-NE2 3.37Å; W256-H259 PolarHBondContact O-N 3.45Å
260F98.1Very high96.3Very high20 Ų2059.9 Ų59.99%0.08832%0.321CS..  trans-76.2133.4-178.3-80.1-116.1000110.8K125 M128 V129 F147 L151 W256 Q264 D265 F268K125-F260 HydrophobicContact CB-CE2 4.23Å; K125-F260 HydrophobicContact CB-CZ 4.08Å; K125-F260 HydrophobicContact CG-CE1 4.45Å; K125-F260 HydrophobicContact CG-CZ 4.34Å; M128-F260 HydrophobicContact CE-CZ 4.41Å; M128-F260 HydrophobicContact SD-CE2 4.24Å; M128-F260 HydrophobicContact SD-CZ 4.19Å; V129-F260 HydrophobicContact CG2-CD2 4.23Å; V129-F260 HydrophobicContact CG2-CE2 3.76Å; F147-F260 AromaticContact CE1-CD2 3.94Å; F147-F260 HydrophobicContact CE1-CD2 3.94Å; F147-F260 HydrophobicContact CE1-CE2 4.03Å; F147-F260 HydrophobicContact CE1-CG 4.3Å; F147-F260 HydrophobicContact CE1-CZ 4.46Å; F147-F260 AromaticContact CZ-CD2 3.72Å; F147-F260 HydrophobicContact CZ-CD2 3.72Å; F147-F260 AromaticContact CZ-CE2 3.6Å; F147-F260 HydrophobicContact CZ-CE2 3.6Å; F147-F260 HydrophobicContact CZ-CZ 4.3Å; L151-F260 HydrophobicContact CD1-CD1 4.33Å; L151-F260 HydrophobicContact CD1-CE1 3.81Å; L151-F260 HydrophobicContact CD1-CZ 4.38Å; W256-F260 HydrophobicContact CB-CD2 3.93Å; W256-F260 HydrophobicContact CB-CE2 4Å; W256-F260 HydrophobicContact CE3-CB 4.24Å; W256-F260 HydrophobicContact CE3-CD2 4.39Å; W256-F260 HydrophobicContact CE3-CG 4.25Å; W256-F260 WeakPolarHBondContact O-CD2 3.43Å; W256-F260 PolarHBondContact O-N 3.26Å; F260-Q264 HydrophobicContact CD1-CB 4.04Å; F260-D265 HydrophobicContact CB-CB 4.39Å; F260-D265 HydrophobicContact CD1-CB 4.38Å; F260-F268 HydrophobicContact CE1-CB 3.97Å; F260-F268 AromaticContact CE1-CD2 3.88Å; F260-F268 HydrophobicContact CE1-CD2 3.88Å; F260-F268 HydrophobicContact CE1-CE2 4.48Å; F260-F268 AromaticContact CE1-CG 3.9Å; F260-F268 HydrophobicContact CE1-CG 3.9Å; F260-F268 HydrophobicContact CZ-CD2 4.17Å; F260-F268 HydrophobicContact CZ-CE2 4.33Å; F260-F268 HydrophobicContact CZ-CG 4.45Å
261S98Very high96.7Very high38 Ų3857.2 Ų57.227%0.26631%0.313SS..  trans-72.5159.8159.8900000110.4E263 Q264 D265S261-E263 VanDerWaalsContact CB-OE2 3.3Å; S261-E263 WeakPolarHBondContact CB-OE2 3.04Å; S261-E263 PolarHBondContact O-N 3.21Å; S261-E263 PolarHBondContact OG-N 3.38Å; S261-E263 PolarHBondContact OG-OE2 3.41Å; S261-Q264 VanDerWaalsContact N-OE1 3.11Å; S261-Q264 PolarHBondContact O-N 3.06Å; S261-Q264 PolarHBondContact OG-N 3.48Å; S261-D265 WeakPolarHBondContact O-CB 3.18Å; S261-D265 PolarHBondContact O-N 3.11Å
262P97.6Very high97.1Very high100 Ų10057.7 Ų57.765%0.64931%0.312SS*.Hα-helixtrans-55-37.2174.4-26.636000113.5D265 F266P262-D265 PolarHBondContact O-N 3.36Å; P262-F266 WeakPolarHBondContact O-CB 3.37Å; P262-F266 PolarHBondContact O-N 3.01Å
263E97.9Very high97.1Very high136 Ų13662.7 Ų62.764%0.63633%0.328SS*.Hα-helixtrans-69.1-41.7179-56.776.2-165.300111.8S261 F266 K267S261-E263 VanDerWaalsContact CB-OE2 3.3Å; S261-E263 WeakPolarHBondContact CB-OE2 3.04Å; S261-E263 PolarHBondContact O-N 3.21Å; S261-E263 PolarHBondContact OG-N 3.38Å; S261-E263 PolarHBondContact OG-OE2 3.41Å; E263-F266 PolarHBondContact O-N 3.13Å; E263-K267 WeakPolarHBondContact O-CB 3.31Å; E263-K267 PolarHBondContact O-N 3.25Å
264Q98.3Very high97.2Very high29 Ų2967.9 Ų67.914%0.13635%0.346CS..Hα-helixtrans-65-42.2176.1-72.4175.5-27.200111.1D148 L151 F260 S261 K267 F268D148-Q264 PolarHBondContact OD1-NE2 2.94Å; L151-Q264 HydrophobicContact CD1-CB 3.79Å; L151-Q264 HydrophobicContact CD1-CG 4.07Å; F260-Q264 HydrophobicContact CD1-CB 4.04Å; S261-Q264 VanDerWaalsContact N-OE1 3.11Å; S261-Q264 PolarHBondContact O-N 3.06Å; S261-Q264 PolarHBondContact OG-N 3.48Å; Q264-K267 PolarHBondContact O-N 2.72Å; Q264-F268 VanDerWaalsContact O-CB 3.23Å; Q264-F268 WeakPolarHBondContact O-CB 3.36Å; Q264-F268 PolarHBondContact O-N 3.02Å
265D97.7Very high97.2Very high44 Ų4469.2 Ų69.224%0.23535%0.348CS..Hα-helixtrans-62.1-46.9176.8-177.138.7000111.9K125 W256 F260 S261 P262 K267 F268 T269K125-D265 WeakPolarHBondContact CE-OD1 3.26Å; K125-D265 IonicContact NZ-OD1 2.81Å; K125-D265 PolarHBondContact NZ-OD1 3.23Å; W256-D265 HydrophobicContact CZ3-CB 4.4Å; W256-D265 WeakPolarHBondContact CZ3-OD1 3.4Å; F260-D265 HydrophobicContact CB-CB 4.39Å; F260-D265 HydrophobicContact CD1-CB 4.38Å; S261-D265 WeakPolarHBondContact O-CB 3.18Å; S261-D265 PolarHBondContact O-N 3.11Å; P262-D265 PolarHBondContact O-N 3.36Å; D265-K267 PolarHBondContact O-N 2.75Å; D265-F268 PolarHBondContact O-N 3.41Å; D265-T269 VanDerWaalsContact O-CB 3.25Å; D265-T269 WeakPolarHBondContact O-CB 3.49Å; D265-T269 PolarHBondContact O-N 3.24Å; D265-T269 PolarHBondContact O-OG1 3.19Å; D265-T269 PolarHBondContact OD1-OG1 3.24Å
266F97Very high97.2Very high159 Ų15970.3 Ų70.370%0.69735%0.353SS*.Hα-helixtrans-58-49.9175.8178.3-95.9000111.6P262 E263 T269 A270P262-F266 WeakPolarHBondContact O-CB 3.37Å; P262-F266 PolarHBondContact O-N 3.01Å; E263-F266 PolarHBondContact O-N 3.13Å; F266-T269 PolarHBondContact O-N 3.02Å; F266-A270 WeakPolarHBondContact O-CB 3.35Å; F266-A270 PolarHBondContact O-N 3.19Å
267K97.8Very high97Very high85 Ų8576 Ų7637%0.3739%0.385SS..Hα-helixtrans-58.7-50.3178.1178.6-177.1-176.71780111.8L151 N152 E263 Q264 D265 T269 A270 V271L151-K267 HydrophobicContact CD2-CD 4.24Å; N152-K267 WeakPolarHBondContact OD1-CE 3.5Å; N152-K267 PolarHBondContact OD1-NZ 2.8Å; E263-K267 WeakPolarHBondContact O-CB 3.31Å; E263-K267 PolarHBondContact O-N 3.25Å; Q264-K267 PolarHBondContact O-N 2.72Å; D265-K267 PolarHBondContact O-N 2.75Å; K267-T269 VanDerWaalsContact C-N 3.35Å; K267-T269 PolarHBondContact O-N 3.48Å; K267-A270 PolarHBondContact O-N 2.98Å; K267-V271 WeakPolarHBondContact O-CG2 3.48Å; K267-V271 PolarHBondContact O-N 3.49Å; K267-V271 VanDerWaalsContact O-N 3.09Å
268F97.9Very high96.8Very high0 Ų074 Ų740%040%0.397CS..Hα-helixtrans-62.6-44.3-177.1-164.9-83.9000111.2P124 K125 M128 L151 F154 L155 F260 Q264 D265 V271 L272P124-F268 HydrophobicContact CB-CE1 4.04Å; P124-F268 HydrophobicContact CB-CZ 4.24Å; P124-F268 HydrophobicContact CG-CE1 4.26Å; K125-F268 HydrophobicContact CB-CE1 4.37Å; K125-F268 HydrophobicContact CD-CD1 4.46Å; K125-F268 HydrophobicContact CG-CD1 3.61Å; K125-F268 HydrophobicContact CG-CE1 3.55Å; K125-F268 HydrophobicContact CG-CG 4.49Å; K125-F268 HydrophobicContact CG-CZ 4.44Å; M128-F268 HydrophobicContact CB-CE2 4.25Å; M128-F268 HydrophobicContact CB-CZ 4.29Å; M128-F268 HydrophobicContact CG-CE2 4.25Å; L151-F268 HydrophobicContact CD1-CD2 4.26Å; L151-F268 HydrophobicContact CD2-CD2 4.38Å; L151-F268 HydrophobicContact CG-CD2 4.01Å; F154-F268 AromaticContact CD1-CE2 3.75Å; F154-F268 HydrophobicContact CD1-CE2 3.75Å; F154-F268 AromaticContact CD1-CZ 3.84Å; F154-F268 HydrophobicContact CD1-CZ 3.84Å; F154-F268 HydrophobicContact CE1-CE2 4.13Å; F154-F268 AromaticContact CE1-CZ 3.72Å; F154-F268 HydrophobicContact CE1-CZ 3.72Å; L155-F268 HydrophobicContact CD1-CD2 4.06Å; L155-F268 HydrophobicContact CD2-CD2 3.59Å; L155-F268 HydrophobicContact CD2-CE2 3.68Å; L155-F268 HydrophobicContact CD2-CG 4.04Å; L155-F268 HydrophobicContact CD2-CZ 4.22Å; L155-F268 HydrophobicContact CG-CD2 3.88Å; L155-F268 HydrophobicContact CG-CE2 4.09Å; F260-F268 HydrophobicContact CE1-CB 3.97Å; F260-F268 AromaticContact CE1-CD2 3.88Å; F260-F268 HydrophobicContact CE1-CD2 3.88Å; F260-F268 HydrophobicContact CE1-CE2 4.48Å; F260-F268 AromaticContact CE1-CG 3.9Å; F260-F268 HydrophobicContact CE1-CG 3.9Å; F260-F268 HydrophobicContact CZ-CD2 4.17Å; F260-F268 HydrophobicContact CZ-CE2 4.33Å; F260-F268 HydrophobicContact CZ-CG 4.45Å; Q264-F268 VanDerWaalsContact O-CB 3.23Å; Q264-F268 WeakPolarHBondContact O-CB 3.36Å; Q264-F268 PolarHBondContact O-N 3.02Å; D265-F268 PolarHBondContact O-N 3.41Å; F268-V271 PolarHBondContact O-N 3.35Å; F268-L272 HydrophobicContact CD1-CD1 3.61Å; F268-L272 HydrophobicContact CD1-CG 4.13Å; F268-L272 HydrophobicContact CE1-CD1 3.37Å; F268-L272 HydrophobicContact CE1-CG 4.06Å; F268-L272 HydrophobicContact CZ-CD1 4.44Å; F268-L272 WeakPolarHBondContact O-CG 3.49Å; F268-L272 PolarHBondContact O-N 3.26Å
269T96.6Very high96.5Very high58 Ų5870.3 Ų70.336%0.35638%0.379SS..Hα-helixtrans-63.9-41.8177.5-57.20000111.6K125 D265 F266 K267 L272 K273K125-T269 VanDerWaalsContact CE-OG1 3.31Å; K125-T269 WeakPolarHBondContact CE-OG1 3.3Å; K125-T269 PolarHBondContact NZ-OG1 3.04Å; D265-T269 VanDerWaalsContact O-CB 3.25Å; D265-T269 WeakPolarHBondContact O-CB 3.49Å; D265-T269 PolarHBondContact O-N 3.24Å; D265-T269 PolarHBondContact O-OG1 3.19Å; D265-T269 PolarHBondContact OD1-OG1 3.24Å; F266-T269 PolarHBondContact O-N 3.02Å; K267-T269 VanDerWaalsContact C-N 3.35Å; K267-T269 PolarHBondContact O-N 3.48Å; T269-L272 PolarHBondContact O-N 2.93Å; T269-K273 WeakPolarHBondContact O-CB 3.36Å; T269-K273 PolarHBondContact O-N 3.5Å
270A96.9Very high96.2Very high47 Ų4775.4 Ų75.439%0.38841%0.409SS..Hα-helixtrans-61.3-47.4177.900000112.1F266 K267 K273 E274F266-A270 WeakPolarHBondContact O-CB 3.35Å; F266-A270 PolarHBondContact O-N 3.19Å; K267-A270 PolarHBondContact O-N 2.98Å; A270-K273 PolarHBondContact O-N 2.98Å; A270-E274 PolarHBondContact O-N 3.12Å
271V97.8Very high95.9Very high37 Ų3775.9 Ų75.922%0.22441%0.411CS..Hα-helixtrans-62.7-46.5178.2173.80000111.2L155 K267 F268 K273 E274 E275L155-V271 HydrophobicContact CB-CG1 4.41Å; L155-V271 HydrophobicContact CD1-CB 4.31Å; L155-V271 HydrophobicContact CD1-CG2 4.17Å; L155-V271 HydrophobicContact CD2-CB 4.14Å; L155-V271 HydrophobicContact CD2-CG1 3.94Å; K267-V271 WeakPolarHBondContact O-CG2 3.48Å; K267-V271 PolarHBondContact O-N 3.49Å; K267-V271 VanDerWaalsContact O-N 3.09Å; F268-V271 PolarHBondContact O-N 3.35Å; V271-K273 VanDerWaalsContact C-N 3.33Å; V271-K273 PolarHBondContact O-N 2.98Å; V271-E274 PolarHBondContact O-N 3.08Å; V271-E275 HydrophobicContact CG1-CG 4.26Å; V271-E275 WeakPolarHBondContact O-CG 3.42Å; V271-E275 PolarHBondContact O-N 3.4Å
272L95.8Very high95.6Very high24 Ų2482.6 Ų82.613%0.12644%0.436CS..Hα-helixtrans-61.3-41.7177.9-75.9-178.4000112.6P124 W164 T165 F268 T269 E274 E275 M276P124-L272 HydrophobicContact CB-CD1 4Å; P124-L272 HydrophobicContact CG-CD1 3.3Å; P124-L272 HydrophobicContact CG-CD2 4.44Å; W164-L272 HydrophobicContact CE3-CD2 4.13Å; W164-L272 HydrophobicContact CZ3-CD2 4.38Å; T165-L272 HydrophobicContact CG2-CD2 3.39Å; F268-L272 HydrophobicContact CD1-CD1 3.61Å; F268-L272 HydrophobicContact CD1-CG 4.13Å; F268-L272 HydrophobicContact CE1-CD1 3.37Å; F268-L272 HydrophobicContact CE1-CG 4.06Å; F268-L272 HydrophobicContact CZ-CD1 4.44Å; F268-L272 WeakPolarHBondContact O-CG 3.49Å; F268-L272 PolarHBondContact O-N 3.26Å; T269-L272 PolarHBondContact O-N 2.93Å; L272-E274 VanDerWaalsContact C-N 3.3Å; L272-E274 PolarHBondContact O-N 3.28Å; L272-E275 PolarHBondContact O-N 3.23Å; L272-M276 VanDerWaalsContact O-CB 3.23Å; L272-M276 WeakPolarHBondContact O-CB 3.47Å; L272-M276 WeakPolarHBondContact O-CG 3.49Å; L272-M276 PolarHBondContact O-N 3.31Å
273K94.8Very high95.4Very high166 Ų16678.6 Ų78.672%0.72241%0.408SS*.Hα-helixtrans-62.7-39.6177.9-175.6175.7-180177.10111.6T269 A270 V271 N277T269-K273 WeakPolarHBondContact O-CB 3.36Å; T269-K273 PolarHBondContact O-N 3.5Å; A270-K273 PolarHBondContact O-N 2.98Å; V271-K273 VanDerWaalsContact C-N 3.33Å; V271-K273 PolarHBondContact O-N 2.98Å; K273-N277 PolarHBondContact O-N 3.25Å; K273-N277 VanDerWaalsContact O-N 3.15Å
274E96.8Very high95Very high152 Ų15275.3 Ų75.371%0.7140%0.399SS*.Hα-helixtrans-65.5-48.6175-176.1177-175.800111.6A270 V271 L272 M276 N277A270-E274 PolarHBondContact O-N 3.12Å; V271-E274 PolarHBondContact O-N 3.08Å; L272-E274 VanDerWaalsContact C-N 3.3Å; L272-E274 PolarHBondContact O-N 3.28Å; E274-M276 VanDerWaalsContact C-N 3.32Å; E274-M276 PolarHBondContact O-N 3.26Å; E274-N277 WeakPolarHBondContact O-CB 3.37Å; E274-N277 PolarHBondContact O-N 2.91Å
275E96.7Very high94.5Very high42 Ų4274.7 Ų74.720%0.19640%0.395CS..Hα-helixtrans-70.6-25.7-176.9-71.7-170.3159.200114.5K163 T165 K169 V271 L272K163-E275 IonicContact NZ-OE1 2.65Å; K163-E275 PolarHBondContact NZ-OE1 3.04Å; T165-E275 WeakPolarHBondContact CB-OE2 3.33Å; T165-E275 HydrophobicContact CG2-CB 3.88Å; T165-E275 WeakPolarHBondContact CG2-OE2 3.04Å; T165-E275 PolarHBondContact OG1-OE2 3.34Å; K169-E275 PolarHBondContact NZ-O 3.28Å; V271-E275 HydrophobicContact CG1-CG 4.26Å; V271-E275 WeakPolarHBondContact O-CG 3.42Å; V271-E275 PolarHBondContact O-N 3.4Å; L272-E275 PolarHBondContact O-N 3.23Å
276M95.3Very high93.9Very high27 Ų2777.1 Ų77.113%0.13341%0.408CS..THydrogen-bonded Turntrans-95.3-0176.3-62.5-62.9-66.600112.6W164 T165 V168 K169 L272 E274 G278 T279 I281 F283W164-M276 HydrophobicContact CZ3-SD 4.37Å; T165-M276 HydrophobicContact CG2-CG 3.88Å; T165-M276 HydrophobicContact CG2-SD 3.73Å; V168-M276 HydrophobicContact CG1-CE 4.19Å; K169-M276 HydrophobicContact CD-SD 4.34Å; K169-M276 HydrophobicContact CG-CE 4.48Å; K169-M276 HydrophobicContact CG-SD 4.17Å; L272-M276 VanDerWaalsContact O-CB 3.23Å; L272-M276 WeakPolarHBondContact O-CB 3.47Å; L272-M276 WeakPolarHBondContact O-CG 3.49Å; L272-M276 PolarHBondContact O-N 3.31Å; E274-M276 VanDerWaalsContact C-N 3.32Å; E274-M276 PolarHBondContact O-N 3.26Å; M276-G278 PolarHBondContact O-N 2.61Å; M276-T279 WeakPolarHBondContact O-CB 3.28Å; M276-T279 WeakPolarHBondContact O-CG2 3.47Å; M276-T279 PolarHBondContact O-N 3.46Å; M276-T279 VanDerWaalsContact O-N 3.13Å; M276-T279 PolarHBondContact O-OG1 3.24Å; M276-I281 HydrophobicContact CE-CB 4.09Å; M276-I281 HydrophobicContact CE-CD1 3.7Å; M276-I281 HydrophobicContact CE-CG1 4.48Å; M276-I281 HydrophobicContact CE-CG2 4.38Å; M276-F283 HydrophobicContact CE-CE2 4.23Å
277N94.1Very high92.5Very high138 Ų13878.5 Ų78.574%0.73842%0.417SS*.THydrogen-bonded Turntrans-58.5138.6178-172.827.8000110.9K273 E274 T279K273-N277 PolarHBondContact O-N 3.25Å; K273-N277 VanDerWaalsContact O-N 3.15Å; E274-N277 WeakPolarHBondContact O-CB 3.37Å; E274-N277 PolarHBondContact O-N 2.91Å; N277-T279 PolarHBondContact O-N 3.06Å
278G92.1Very high90.7Very high74 Ų7481.5 Ų81.576%0.76343%0.432SS*.THydrogen-bonded Turntrans77.6-2.6-176.900000115.1M276M276-G278 PolarHBondContact O-N 2.61Å
279T92.8Very high90.3Very high44 Ų4485.6 Ų85.627%0.2745%0.454SS..  trans-87.2149170.8770000110.9K169 M276 N277 I281K169-T279 HydrophobicContact CD-CG2 3.95Å; K169-T279 HydrophobicContact CG-CG2 4.02Å; M276-T279 WeakPolarHBondContact O-CB 3.28Å; M276-T279 WeakPolarHBondContact O-CG2 3.47Å; M276-T279 PolarHBondContact O-N 3.46Å; M276-T279 VanDerWaalsContact O-N 3.13Å; M276-T279 PolarHBondContact O-OG1 3.24Å; N277-T279 PolarHBondContact O-N 3.06Å; T279-I281 VanDerWaalsContact C-N 3.28Å; T279-I281 HydrophobicContact CG2-CD1 4.29Å
280N90.4Very high90Very high164 Ų16487.1 Ų87.188%0.87746%0.459SS*.  trans-94.418.2172.3-68.9-30.9000112.3K282N280-K282 PolarHBondContact O-N 3.08Å
281I92Very high89.6Confident29 Ų2989.3 Ų89.315%0.14946%0.463CS..  trans-80.2124.2-176.2-55.6164.8000107.6V168 K169 R172 M276 T279 F283V168-I281 HydrophobicContact CG1-CD1 4.21Å; K169-I281 HydrophobicContact CG-CD1 4.25Å; R172-I281 HydrophobicContact CB-CD1 4.08Å; R172-I281 HydrophobicContact CB-CG1 4.33Å; R172-I281 HydrophobicContact CG-CD1 3.62Å; R172-I281 HydrophobicContact CG-CG1 3.81Å; M276-I281 HydrophobicContact CE-CB 4.09Å; M276-I281 HydrophobicContact CE-CD1 3.7Å; M276-I281 HydrophobicContact CE-CG1 4.48Å; M276-I281 HydrophobicContact CE-CG2 4.38Å; T279-I281 VanDerWaalsContact C-N 3.28Å; T279-I281 HydrophobicContact CG2-CD1 4.29Å; I281-F283 HydrophobicContact CB-CE2 4.49Å; I281-F283 HydrophobicContact CG2-CD2 4.26Å; I281-F283 HydrophobicContact CG2-CE1 3.96Å; I281-F283 HydrophobicContact CG2-CE2 3.47Å; I281-F283 VanDerWaalsContact CG2-CE2 3.47Å; I281-F283 HydrophobicContact CG2-CZ 3.29Å
282K90.7Very high89.1Confident180 Ų18092.4 Ų92.478%0.78348%0.477SS*.  trans-118.3141.5175.9-62.9-173.8178.1-173.60110N280N280-K282 PolarHBondContact O-N 3.08Å
283F93.2Very high88.7Confident15 Ų1596.6 Ų96.67%0.06650%0.499CS..  trans-122.5153.5177.8-62.7-70.5000112.1T121 W164 V168 M276 I281 W285 D286T121-F283 HydrophobicContact CG2-CE1 4.08Å; W164-F283 HydrophobicContact CH2-CD2 4.39Å; W164-F283 AromaticContact CH2-CE2 3.68Å; W164-F283 HydrophobicContact CH2-CE2 3.68Å; W164-F283 AromaticContact CH2-CZ 3.88Å; W164-F283 HydrophobicContact CH2-CZ 3.88Å; W164-F283 HydrophobicContact CZ2-CE2 4.5Å; W164-F283 HydrophobicContact CZ2-CZ 4.34Å; V168-F283 HydrophobicContact CG1-CE2 4.38Å; V168-F283 HydrophobicContact CG1-CZ 3.65Å; M276-F283 HydrophobicContact CE-CE2 4.23Å; I281-F283 HydrophobicContact CB-CE2 4.49Å; I281-F283 HydrophobicContact CG2-CD2 4.26Å; I281-F283 HydrophobicContact CG2-CE1 3.96Å; I281-F283 HydrophobicContact CG2-CE2 3.47Å; I281-F283 VanDerWaalsContact CG2-CE2 3.47Å; I281-F283 HydrophobicContact CG2-CZ 3.29Å; F283-W285 HydrophobicContact CB-CD2 3.62Å; F283-W285 HydrophobicContact CB-CE3 3.97Å; F283-W285 HydrophobicContact CB-CG 4.19Å; F283-W285 HydrophobicContact CB-CH2 3.84Å; F283-W285 HydrophobicContact CB-CZ2 3.46Å; F283-W285 VanDerWaalsContact CB-CZ2 3.46Å; F283-W285 HydrophobicContact CB-CZ3 4.04Å; F283-W285 AromaticContact CD1-CH2 3.26Å; F283-W285 HydrophobicContact CD1-CH2 3.26Å; F283-W285 AromaticContact CD1-CZ2 3.32Å; F283-W285 HydrophobicContact CD1-CZ2 3.32Å; F283-W285 HydrophobicContact CD1-CZ3 4.02Å; F283-W285 HydrophobicContact CD2-CH2 4.47Å; F283-W285 AromaticContact CD2-CZ2 3.69Å; F283-W285 HydrophobicContact CD2-CZ2 3.69Å; F283-W285 AromaticContact CE1-CH2 3.87Å; F283-W285 HydrophobicContact CE1-CH2 3.87Å; F283-W285 AromaticContact CE1-CZ2 3.91Å; F283-W285 HydrophobicContact CE1-CZ2 3.91Å; F283-W285 HydrophobicContact CE2-CZ2 4.22Å; F283-W285 HydrophobicContact CG-CD2 4.33Å; F283-W285 AromaticContact CG-CE2 3.56Å; F283-W285 AromaticContact CG-CH2 3.62Å; F283-W285 HydrophobicContact CG-CH2 3.62Å; F283-W285 AromaticContact CG-CZ2 3.18Å; F283-W285 HydrophobicContact CG-CZ2 3.18Å; F283-W285 HydrophobicContact CG-CZ3 4.3Å; F283-W285 AromaticContact CG-NE1 3.97Å; F283-W285 HydrophobicContact CZ-CZ2 4.31Å; F283-W285 PolarHBondContact O-N 3.34Å; F283-W285 VanDerWaalsContact O-N 3.14Å; F283-D286 PolarHBondContact N-OD2 3.18Å; F283-D286 WeakPolarHBondContact O-CB 3.45Å; F283-D286 PolarHBondContact O-N 3.09Å; F283-D286 VanDerWaalsContact O-N 3.13Å
284P89.8Confident88.3Confident67 Ų6792 Ų9244%0.43548%0.484SS..THydrogen-bonded Turntrans-59.8-23.4177-24.234.6000114.3T184T184-P284 HydrophobicContact CG2-CG 3.99Å
285W89.1Confident87.7Confident17 Ų1787.7 Ų87.76%0.06447%0.468CS..THydrogen-bonded Turntrans-941.6-179.460.474000113.8R122 N123 W164 T184 E186 F283 E287 E288R122-W285 VanDerWaalsContact C-CH2 3.41Å; N123-W285 HydrophobicContact CB-CB 4.43Å; N123-W285 HydrophobicContact CB-CD2 3.77Å; N123-W285 HydrophobicContact CB-CE3 4.1Å; N123-W285 HydrophobicContact CB-CG 3.92Å; N123-W285 WeakPolarHBondContact ND2-CB 3.33Å; W164-W285 HydrophobicContact CH2-CZ2 4.22Å; W164-W285 AromaticContact CZ2-CZ2 3.99Å; W164-W285 HydrophobicContact CZ2-CZ2 3.99Å; T184-W285 HydrophobicContact CG2-CZ3 4.07Å; E186-W285 VanDerWaalsContact CD-CZ3 3.49Å; E186-W285 HydrophobicContact CG-CE3 4.02Å; E186-W285 WeakPolarHBondContact OE2-CZ3 3.3Å; F283-W285 HydrophobicContact CB-CD2 3.62Å; F283-W285 HydrophobicContact CB-CE3 3.97Å; F283-W285 HydrophobicContact CB-CG 4.19Å; F283-W285 HydrophobicContact CB-CH2 3.84Å; F283-W285 HydrophobicContact CB-CZ2 3.46Å; F283-W285 VanDerWaalsContact CB-CZ2 3.46Å; F283-W285 HydrophobicContact CB-CZ3 4.04Å; F283-W285 AromaticContact CD1-CH2 3.26Å; F283-W285 HydrophobicContact CD1-CH2 3.26Å; F283-W285 AromaticContact CD1-CZ2 3.32Å; F283-W285 HydrophobicContact CD1-CZ2 3.32Å; F283-W285 HydrophobicContact CD1-CZ3 4.02Å; F283-W285 HydrophobicContact CD2-CH2 4.47Å; F283-W285 AromaticContact CD2-CZ2 3.69Å; F283-W285 HydrophobicContact CD2-CZ2 3.69Å; F283-W285 AromaticContact CE1-CH2 3.87Å; F283-W285 HydrophobicContact CE1-CH2 3.87Å; F283-W285 AromaticContact CE1-CZ2 3.91Å; F283-W285 HydrophobicContact CE1-CZ2 3.91Å; F283-W285 HydrophobicContact CE2-CZ2 4.22Å; F283-W285 HydrophobicContact CG-CD2 4.33Å; F283-W285 AromaticContact CG-CE2 3.56Å; F283-W285 AromaticContact CG-CH2 3.62Å; F283-W285 HydrophobicContact CG-CH2 3.62Å; F283-W285 AromaticContact CG-CZ2 3.18Å; F283-W285 HydrophobicContact CG-CZ2 3.18Å; F283-W285 HydrophobicContact CG-CZ3 4.3Å; F283-W285 AromaticContact CG-NE1 3.97Å; F283-W285 HydrophobicContact CZ-CZ2 4.31Å; F283-W285 PolarHBondContact O-N 3.34Å; F283-W285 VanDerWaalsContact O-N 3.14Å; W285-E287 PolarHBondContact O-N 2.68Å; W285-E288 PolarHBondContact O-N 2.95Å
286D83.8Confident87Confident95 Ų9591.2 Ų91.251%0.50849%0.489SS..THydrogen-bonded Turntrans-71.9-14.1176.2-66.1-24.3000112F283F283-D286 PolarHBondContact N-OD2 3.18Å; F283-D286 WeakPolarHBondContact O-CB 3.45Å; F283-D286 PolarHBondContact O-N 3.09Å; F283-D286 VanDerWaalsContact O-N 3.13Å
287E67.9Low86.3Confident188 Ų18896.6 Ų96.688%0.87952%0.519SS*.THydrogen-bonded Turntrans-94.7-2.6177.5-60.3-176.3179.400113.3W285W285-E287 PolarHBondContact O-N 2.68Å
288E59.8Low85.6Confident148 Ų14892.8 Ų92.869%0.69250%0.499SS*.  trans-95.30178.4-68.1-168.9-15500113.4K257 W285K257-E288 IonicContact NZ-OE2 3.2Å; K257-E288 PolarHBondContact NZ-OE2 2.68Å; W285-E288 PolarHBondContact O-N 2.95Å

Retrieved 288 of 288 residues in 1103.3 ms (Link to these results)