A0A060XZA9_ONCMY Loading...

Aldehyde dehydrogenase

AlphaFold DB , UniProt , Accession A0A060XZA9, Species ONCMY (Oncorhynchus mykiss, Rainbow trout), Gene n/a, Length 494 aa.

Structure Viewer
Loading PAE data...
(Predicted Aligned Error values between residue pairs)
Error loading PAE data: please refresh the page.

Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M82.4Confident95.5Very high146 Ų14667.2 Ų67.272%0.71932%0.32SS*.  0-39.50177.3177.958.800110.8Q4 T5M1-Q4 PolarHBondContact O-N 3.47Å; M1-T5 PolarHBondContact O-N 3.36Å; M1-T5 VanDerWaalsContact O-N 3.12Å; M1-T5 PolarHBondContact O-OG1 2.99Å
2E92.2Very high95.7Very high22 Ų2261.9 Ų61.910%0.10330%0.296CS..Hα-helixtrans-53.6-55.6177.8-59.966.2-14400111.6Q4 T5 V6 V164 E173 L174E2-Q4 VanDerWaalsContact C-N 3.32Å; E2-Q4 PolarHBondContact O-N 2.86Å; E2-T5 WeakPolarHBondContact O-CB 3.34Å; E2-T5 PolarHBondContact O-N 3.42Å; E2-V6 WeakPolarHBondContact O-CG2 3.3Å; E2-V6 PolarHBondContact O-N 3.34Å; E2-V164 HydrophobicContact CG-CG1 4.37Å; E2-E173 HydrophobicContact CB-CG 3.97Å; E2-E173 HydrophobicContact CG-CB 4.15Å; E2-E173 HydrophobicContact CG-CG 4.02Å; E2-L174 HydrophobicContact CB-CD1 4.12Å; E2-L174 HydrophobicContact CG-CB 4.48Å
3K94.3Very high96Very high110 Ų11059.7 Ų59.748%0.47829%0.285SS..Hα-helixtrans-52-49.9177.4179.1175.9-172.4-580112.3T5 V6 D7K3-T5 VanDerWaalsContact C-N 3.28Å; K3-T5 PolarHBondContact O-N 3.42Å; K3-V6 PolarHBondContact O-N 2.89Å; K3-V6 VanDerWaalsContact O-N 3.17Å; K3-D7 IonicContact NZ-OD1 2.74Å; K3-D7 IonicContact NZ-OD2 3.7Å; K3-D7 PolarHBondContact NZ-OD2 2.98Å; K3-D7 VanDerWaalsContact O-CG 3.26Å; K3-D7 PolarHBondContact O-N 2.98Å
4Q95.7Very high96.2Very high116 Ų11664.4 Ų64.454%0.54231%0.311SS..Hα-helixtrans-62.1-37.6-179-172.8-1786.700111.8M1 E2 D7 F8M1-Q4 PolarHBondContact O-N 3.47Å; E2-Q4 VanDerWaalsContact C-N 3.32Å; E2-Q4 PolarHBondContact O-N 2.86Å; Q4-D7 PolarHBondContact O-N 3.49Å; Q4-F8 HydrophobicContact CG-CD2 3.91Å; Q4-F8 HydrophobicContact CG-CE2 3.41Å; Q4-F8 VanDerWaalsContact CG-CE2 3.41Å; Q4-F8 HydrophobicContact CG-CZ 3.88Å; Q4-F8 WeakPolarHBondContact O-CD2 3.34Å; Q4-F8 WeakPolarHBondContact O-CG 3.49Å; Q4-F8 PolarHBondContact O-N 3.28Å
5T96.6Very high96.3Very high28 Ų2865.9 Ų65.917%0.17233%0.326CS..Hα-helixtrans-66.4-40.7176.3-610000111.8M1 E2 K3 A9 P162 V164M1-T5 PolarHBondContact O-N 3.36Å; M1-T5 VanDerWaalsContact O-N 3.12Å; M1-T5 PolarHBondContact O-OG1 2.99Å; E2-T5 WeakPolarHBondContact O-CB 3.34Å; E2-T5 PolarHBondContact O-N 3.42Å; K3-T5 VanDerWaalsContact C-N 3.28Å; K3-T5 PolarHBondContact O-N 3.42Å; T5-A9 PolarHBondContact O-N 2.97Å; T5-A9 VanDerWaalsContact O-N 3.08Å; T5-P162 HydrophobicContact CG2-CB 3.54Å; T5-P162 HydrophobicContact CG2-CG 3.49Å; T5-P162 VanDerWaalsContact CG2-CG 3.49Å; T5-V164 HydrophobicContact CG2-CG2 3.73Å
6V98.3Very high96.5Very high3 Ų362.8 Ų62.82%0.01832%0.316CS..Hα-helixtrans-66.8-42.7176.1178.50000111.2E2 K3 A9 R10 V134 L174 Q177 F179E2-V6 WeakPolarHBondContact O-CG2 3.3Å; E2-V6 PolarHBondContact O-N 3.34Å; K3-V6 PolarHBondContact O-N 2.89Å; K3-V6 VanDerWaalsContact O-N 3.17Å; V6-A9 PolarHBondContact O-N 3.01Å; V6-R10 WeakPolarHBondContact O-CB 3.36Å; V6-R10 PolarHBondContact O-N 3.37Å; V6-V134 HydrophobicContact CG2-CG2 4.31Å; V6-L174 HydrophobicContact CG2-CD1 3.66Å; V6-Q177 HydrophobicContact CB-CB 4.26Å; V6-Q177 HydrophobicContact CB-CG 4.4Å; V6-Q177 HydrophobicContact CG1-CB 4.07Å; V6-Q177 HydrophobicContact CG2-CB 3.98Å; V6-Q177 HydrophobicContact CG2-CG 3.97Å; V6-F179 HydrophobicContact CG1-CE1 4.08Å; V6-F179 HydrophobicContact CG1-CZ 4.22Å; V6-F179 HydrophobicContact CG2-CE1 3.92Å; V6-F179 HydrophobicContact CG2-CE2 4.39Å; V6-F179 HydrophobicContact CG2-CZ 3.49Å; V6-F179 VanDerWaalsContact CG2-CZ 3.49Å
7D97.9Very high96.5Very high57 Ų5763.4 Ų63.431%0.30531%0.314SS..Hα-helixtrans-60.2-46.4177.1-68.7-22.4000110.5K3 Q4 A9 R10 D11K3-D7 IonicContact NZ-OD1 2.74Å; K3-D7 IonicContact NZ-OD2 3.7Å; K3-D7 PolarHBondContact NZ-OD2 2.98Å; K3-D7 VanDerWaalsContact O-CG 3.26Å; K3-D7 PolarHBondContact O-N 2.98Å; Q4-D7 PolarHBondContact O-N 3.49Å; D7-A9 PolarHBondContact O-N 3.29Å; D7-R10 WeakPolarHBondContact O-CB 3.42Å; D7-R10 PolarHBondContact O-N 2.89Å; D7-D11 PolarHBondContact O-N 2.94Å
8F97Very high96.6Very high106 Ų10659.8 Ų59.847%0.46530%0.296SS..Hα-helixtrans-61.7-42176.3-71.6-40.6000113.5Q4 R10 D11 A12Q4-F8 HydrophobicContact CG-CD2 3.91Å; Q4-F8 HydrophobicContact CG-CE2 3.41Å; Q4-F8 VanDerWaalsContact CG-CE2 3.41Å; Q4-F8 HydrophobicContact CG-CZ 3.88Å; Q4-F8 WeakPolarHBondContact O-CD2 3.34Å; Q4-F8 WeakPolarHBondContact O-CG 3.49Å; Q4-F8 PolarHBondContact O-N 3.28Å; F8-R10 VanDerWaalsContact C-N 3.29Å; F8-R10 PolarHBondContact O-N 3.44Å; F8-D11 PolarHBondContact O-N 3.39Å; F8-A12 WeakPolarHBondContact O-CB 3.41Å; F8-A12 PolarHBondContact O-N 2.97Å
9A98.6Very high96.7Very high0 Ų062.9 Ų62.90%031%0.31CS..Hα-helixtrans-64.5-36.3176.300000112.3T5 V6 D7 F13 V105 A132 V134 E159 P162T5-A9 PolarHBondContact O-N 2.97Å; T5-A9 VanDerWaalsContact O-N 3.08Å; V6-A9 PolarHBondContact O-N 3.01Å; D7-A9 PolarHBondContact O-N 3.29Å; A9-F13 WeakPolarHBondContact O-CB 3.24Å; A9-F13 PolarHBondContact O-N 3.32Å; A9-V105 HydrophobicContact CB-CG1 4.19Å; A9-A132 HydrophobicContact CB-CB 4.41Å; A9-V134 HydrophobicContact CB-CG2 4.16Å; A9-E159 WeakPolarHBondContact CA-O 3.22Å; A9-P162 HydrophobicContact CB-CG 4.18Å
10R98.8Very high96.8Very high54 Ų5463.4 Ų63.420%0.20432%0.318CS..Hα-helixtrans-67.9-45.8175.6-170.3166.4-67.4-74.1-4.4111.6V6 D7 F8 A12 F13 L14 V105 R178 D180V6-R10 WeakPolarHBondContact O-CB 3.36Å; V6-R10 PolarHBondContact O-N 3.37Å; D7-R10 WeakPolarHBondContact O-CB 3.42Å; D7-R10 PolarHBondContact O-N 2.89Å; F8-R10 VanDerWaalsContact C-N 3.29Å; F8-R10 PolarHBondContact O-N 3.44Å; R10-A12 VanDerWaalsContact C-N 3.33Å; R10-A12 PolarHBondContact O-N 2.92Å; R10-F13 WeakPolarHBondContact O-CB 3.47Å; R10-F13 PolarHBondContact O-N 3.33Å; R10-L14 HydrophobicContact CG-CD1 4.29Å; R10-L14 VanDerWaalsContact O-CG 3.29Å; R10-L14 WeakPolarHBondContact O-CG 3.34Å; R10-L14 PolarHBondContact O-N 2.87Å; R10-V105 HydrophobicContact CB-CG2 3.86Å; R10-V105 HydrophobicContact CG-CG2 4.22Å; R10-R178 PolarHBondContact NH2-O 2.94Å; R10-D180 IonicContact CZ-OD2 3.62Å; R10-D180 IonicContact NH1-OD1 2.66Å; R10-D180 IonicContact NH1-OD2 2.76Å; R10-D180 PolarHBondContact NH1-OD2 3.46Å; R10-D180 IonicContact NH2-OD2 3.96Å; R10-D180 PolarHBondContact NH2-OD2 2.99Å
11D98.6Very high96.9Very high97 Ų9763.3 Ų63.352%0.51932%0.318SS..Hα-helixtrans-60.5-44.2176.4-70.8-17.5000111.1D7 F8 F13 L14 T15D7-D11 PolarHBondContact O-N 2.94Å; F8-D11 PolarHBondContact O-N 3.39Å; D11-F13 PolarHBondContact O-N 3.42Å; D11-L14 PolarHBondContact O-N 3.41Å; D11-T15 WeakPolarHBondContact O-CG2 3.48Å; D11-T15 PolarHBondContact O-N 2.91Å
12A98.6Very high97.7Very high4 Ų464.9 Ų64.93%0.03332%0.321CS..Hα-helixtrans-61.1-42.5175.600000112.3F8 R10 T15 E159 L160F8-A12 WeakPolarHBondContact O-CB 3.41Å; F8-A12 PolarHBondContact O-N 2.97Å; R10-A12 VanDerWaalsContact C-N 3.33Å; R10-A12 PolarHBondContact O-N 2.92Å; A12-T15 WeakPolarHBondContact O-CB 3.46Å; A12-T15 PolarHBondContact O-N 2.86Å; A12-T15 PolarHBondContact O-OG1 3.38Å; A12-E159 HydrophobicContact CB-CB 3.79Å; A12-L160 HydrophobicContact CB-CD2 3.78Å; A12-L160 HydrophobicContact CB-CG 4.01Å
13F98.9Very high98Very high33 Ų3365.5 Ų65.515%0.14532%0.323CS..Hα-helixtrans-60.5-44.3174.4173.9-102.5000112A9 R10 D11 T15 G16 P102 A132 L160A9-F13 WeakPolarHBondContact O-CB 3.24Å; A9-F13 PolarHBondContact O-N 3.32Å; R10-F13 WeakPolarHBondContact O-CB 3.47Å; R10-F13 PolarHBondContact O-N 3.33Å; D11-F13 PolarHBondContact O-N 3.42Å; F13-T15 PolarHBondContact O-N 3.37Å; F13-G16 PolarHBondContact O-N 3.3Å; F13-P102 HydrophobicContact CE2-CB 3.89Å; F13-P102 HydrophobicContact CE2-CG 3.92Å; F13-P102 HydrophobicContact CZ-CB 4.21Å; F13-P102 HydrophobicContact CZ-CG 4.03Å; F13-A132 HydrophobicContact CB-CB 3.94Å; F13-L160 HydrophobicContact CB-CD2 4.4Å
14L98.8Very high98.2Very high125 Ų12561.1 Ų61.165%0.65430%0.304SS*.Hα-helixtrans-66.1-19.1-178-70.4172.7000113.6R10 D11 G16R10-L14 HydrophobicContact CG-CD1 4.29Å; R10-L14 VanDerWaalsContact O-CG 3.29Å; R10-L14 WeakPolarHBondContact O-CG 3.34Å; R10-L14 PolarHBondContact O-N 2.87Å; D11-L14 PolarHBondContact O-N 3.41Å; L14-G16 PolarHBondContact O-N 2.86Å
15T98.6Very high98.4Very high88 Ų8857.3 Ų57.354%0.5429%0.288SS..THydrogen-bonded Turntrans-62.9-18.1169.372.50000113.2D11 A12 F13 R17D11-T15 WeakPolarHBondContact O-CG2 3.48Å; D11-T15 PolarHBondContact O-N 2.91Å; A12-T15 WeakPolarHBondContact O-CB 3.46Å; A12-T15 PolarHBondContact O-N 2.86Å; A12-T15 PolarHBondContact O-OG1 3.38Å; F13-T15 PolarHBondContact O-N 3.37Å; T15-R17 PolarHBondContact O-N 2.9Å; T15-R17 WeakPolarHBondContact OG1-CG 3.28Å; T15-R17 PolarHBondContact OG1-N 2.96Å
16G98.3Very high98.5Very high16 Ų1661.4 Ų61.417%0.16531%0.306CS..THydrogen-bonded Turntrans76.73.2-17700000114.2F13 L14 S18 Q19 P20F13-G16 PolarHBondContact O-N 3.3Å; L14-G16 PolarHBondContact O-N 2.86Å; G16-S18 PolarHBondContact O-N 3.48Å; G16-Q19 VanDerWaalsContact O-CB 3.25Å; G16-Q19 WeakPolarHBondContact O-CB 3.45Å; G16-Q19 WeakPolarHBondContact O-CG 3.39Å; G16-Q19 PolarHBondContact O-N 2.93Å; G16-P20 WeakPolarHBondContact O-CD 3.46Å
17R97.8Very high98.5Very high72 Ų7261.9 Ų61.927%0.27231%0.307SS..THydrogen-bonded Turntrans-66-20.8-175.277.3-172-174.2-149.10.8114.5T15 Q19 P20 F23 D157 E159 L160T15-R17 PolarHBondContact O-N 2.9Å; T15-R17 WeakPolarHBondContact OG1-CG 3.28Å; T15-R17 PolarHBondContact OG1-N 2.96Å; R17-Q19 VanDerWaalsContact C-N 3.35Å; R17-P20 WeakPolarHBondContact O-CD 3.34Å; R17-F23 HydrophobicContact CG-CZ 4.46Å; R17-F23 WeakPolarHBondContact O-CB 3.39Å; R17-F23 WeakPolarHBondContact O-CD1 3.31Å; R17-F23 WeakPolarHBondContact O-CG 3.44Å; R17-D157 IonicContact CZ-OD1 2.83Å; R17-D157 IonicContact CZ-OD2 3.34Å; R17-D157 IonicContact NE-OD2 3.44Å; R17-D157 PolarHBondContact NE-OD2 3.44Å; R17-D157 IonicContact NH2-OD1 3.37Å; R17-D157 PolarHBondContact NH2-OD1 3.49Å; R17-D157 IonicContact NH2-OD2 2.73Å; R17-D157 PolarHBondContact NH2-OD2 3.48Å; R17-E159 IonicContact CZ-OE2 3.72Å; R17-E159 VanDerWaalsContact CZ-OE2 3.25Å; R17-E159 IonicContact NH1-OE2 3.07Å; R17-E159 PolarHBondContact NH1-OE2 3.21Å; R17-E159 IonicContact NH2-OE2 3.4Å; R17-E159 PolarHBondContact NH2-OE2 2.86Å; R17-L160 HydrophobicContact CG-CD1 3.96Å
18S98.4Very high98.6Very high0 Ų059.1 Ų59.10%029%0.293CS..THydrogen-bonded Turntrans-81-10.8172.265.30000113.8G16 R24 G130G16-S18 PolarHBondContact O-N 3.48Å; S18-R24 WeakPolarHBondContact O-CG 3.35Å; S18-R24 PolarHBondContact O-NE 3.28Å; S18-G130 WeakPolarHBondContact CB-O 3.34Å; S18-G130 PolarHBondContact OG-O 3.28Å
19Q97.6Very high98.6Very high119 Ų11959.9 Ų59.956%0.55630%0.296SS*.SBendtrans-67.2-46.2-177.8-64.2-177.44.800113.5G16 R17 L21 R24G16-Q19 VanDerWaalsContact O-CB 3.25Å; G16-Q19 WeakPolarHBondContact O-CB 3.45Å; G16-Q19 WeakPolarHBondContact O-CG 3.39Å; G16-Q19 PolarHBondContact O-N 2.93Å; R17-Q19 VanDerWaalsContact C-N 3.35Å; Q19-L21 PolarHBondContact O-N 2.98Å; Q19-R24 PolarHBondContact O-NE 3.34Å; Q19-R24 PolarHBondContact O-NH2 3.04Å
20P98.7Very high98.7Very high72 Ų7260.4 Ų60.447%0.46830%0.3SS..SBendtrans-63.3130.3-177.7-22.835000112.3G16 R17 K22 F23 R24G16-P20 WeakPolarHBondContact O-CD 3.46Å; R17-P20 WeakPolarHBondContact O-CD 3.34Å; P20-K22 PolarHBondContact O-N 2.7Å; P20-K22 VanDerWaalsContact O-N 3.13Å; P20-F23 WeakPolarHBondContact O-CB 3.19Å; P20-F23 PolarHBondContact O-N 2.93Å; P20-R24 PolarHBondContact O-N 3.3Å
21L98.8Very high98.7Very high62 Ų6257.9 Ų57.933%0.32529%0.29SS..Hα-helixtrans-56.7-33.9179.2-58.5-175.5000112.6Q19 F23 R24 V25 L76 A80Q19-L21 PolarHBondContact O-N 2.98Å; L21-F23 VanDerWaalsContact C-N 3.32Å; L21-F23 PolarHBondContact O-N 3.16Å; L21-R24 PolarHBondContact O-N 2.96Å; L21-V25 WeakPolarHBondContact O-CG2 3.38Å; L21-V25 PolarHBondContact O-N 3.42Å; L21-L76 HydrophobicContact CB-CD2 4.49Å; L21-L76 HydrophobicContact CD2-CD1 4.37Å; L21-L76 HydrophobicContact CD2-CD2 4.35Å; L21-L76 HydrophobicContact CD2-CG 4.12Å; L21-A80 HydrophobicContact CD1-CB 4.26Å; L21-A80 HydrophobicContact CD2-CB 3.68Å
22K98.8Very high98.7Very high179 Ų17955 Ų5578%0.77827%0.274SS*.Hα-helixtrans-58.9-42176.5-173.9-179.5178-176.60112.2P20 Q26P20-K22 PolarHBondContact O-N 2.7Å; P20-K22 VanDerWaalsContact O-N 3.13Å; K22-Q26 PolarHBondContact O-N 2.92Å
23F98.9Very high98.7Very high35 Ų3560.4 Ų60.415%0.15429%0.293CS..Hα-helixtrans-64.7-46.2177.3179.5-90.1000110.6R17 P20 L21 V25 Q26 Q27 D157 L160R17-F23 HydrophobicContact CG-CZ 4.46Å; R17-F23 WeakPolarHBondContact O-CB 3.39Å; R17-F23 WeakPolarHBondContact O-CD1 3.31Å; R17-F23 WeakPolarHBondContact O-CG 3.44Å; P20-F23 WeakPolarHBondContact O-CB 3.19Å; P20-F23 PolarHBondContact O-N 2.93Å; L21-F23 VanDerWaalsContact C-N 3.32Å; L21-F23 PolarHBondContact O-N 3.16Å; F23-V25 PolarHBondContact O-N 3.06Å; F23-Q26 WeakPolarHBondContact O-CB 3.32Å; F23-Q26 PolarHBondContact O-N 2.77Å; F23-Q26 VanDerWaalsContact O-N 3.09Å; F23-Q27 HydrophobicContact CD1-CG 3.93Å; F23-Q27 HydrophobicContact CE1-CG 3.48Å; F23-Q27 VanDerWaalsContact CE1-CG 3.48Å; F23-Q27 HydrophobicContact CE2-CG 4.49Å; F23-Q27 HydrophobicContact CZ-CG 3.81Å; F23-Q27 WeakPolarHBondContact O-CG 3.36Å; F23-Q27 PolarHBondContact O-N 3.05Å; F23-D157 HydrophobicContact CZ-CB 4.07Å; F23-L160 HydrophobicContact CE1-CD1 3.53Å; F23-L160 HydrophobicContact CZ-CD1 3.59Å
24R98.8Very high98.6Very high18 Ų1858.9 Ų58.97%0.06829%0.287CS..Hα-helixtrans-59-45.6178.2-54-177.1-160.6-170.61.1111.8S18 Q19 P20 L21 Q26 Q27 L28 L76 I127 A128 A129S18-R24 WeakPolarHBondContact O-CG 3.35Å; S18-R24 PolarHBondContact O-NE 3.28Å; Q19-R24 PolarHBondContact O-NE 3.34Å; Q19-R24 PolarHBondContact O-NH2 3.04Å; P20-R24 PolarHBondContact O-N 3.3Å; L21-R24 PolarHBondContact O-N 2.96Å; R24-Q26 VanDerWaalsContact C-N 3.31Å; R24-Q26 PolarHBondContact O-N 3.47Å; R24-Q27 PolarHBondContact O-N 2.58Å; R24-L28 WeakPolarHBondContact O-CG 3.19Å; R24-L28 PolarHBondContact O-N 2.8Å; R24-L76 HydrophobicContact CB-CD2 3.81Å; R24-I127 WeakPolarHBondContact CD-O 3.42Å; R24-A128 WeakPolarHBondContact CD-O 3.27Å; R24-A128 PolarHBondContact NH1-O 3.04Å; R24-A129 PolarHBondContact NH1-O 3.19Å
25V98.9Very high98.6Very high35 Ų3553 Ų5321%0.21226%0.256CS..Hα-helixtrans-60-40.5174.8171.70000111.6L21 F23 L28 K29 V73 L76L21-V25 WeakPolarHBondContact O-CG2 3.38Å; L21-V25 PolarHBondContact O-N 3.42Å; F23-V25 PolarHBondContact O-N 3.06Å; V25-L28 PolarHBondContact O-N 3.41Å; V25-K29 HydrophobicContact CG1-CD 4.09Å; V25-K29 HydrophobicContact CG1-CG 4.4Å; V25-K29 WeakPolarHBondContact O-CB 3.39Å; V25-K29 WeakPolarHBondContact O-CG 3.31Å; V25-K29 PolarHBondContact O-N 3.24Å; V25-V73 HydrophobicContact CG1-CG1 4.14Å; V25-V73 HydrophobicContact CG1-CG2 4.49Å; V25-L76 HydrophobicContact CG2-CD2 3.87Å
26Q98.9Very high98.5Very high115 Ų11552.4 Ų52.454%0.53725%0.252SS..Hα-helixtrans-62.6-45.8177.3-179180-5.500111.6K22 F23 R24 K29 S30K22-Q26 PolarHBondContact O-N 2.92Å; F23-Q26 WeakPolarHBondContact O-CB 3.32Å; F23-Q26 PolarHBondContact O-N 2.77Å; F23-Q26 VanDerWaalsContact O-N 3.09Å; R24-Q26 VanDerWaalsContact C-N 3.31Å; R24-Q26 PolarHBondContact O-N 3.47Å; Q26-K29 PolarHBondContact O-N 3.08Å; Q26-S30 PolarHBondContact O-N 3.31Å
27Q98.9Very high98.5Very high12 Ų1256.4 Ų56.46%0.05627%0.266CS..Hα-helixtrans-62.2-45177.1-63.8-60.8-4400111.5F23 R24 K29 S30 L31 I127 L156 Y161F23-Q27 HydrophobicContact CD1-CG 3.93Å; F23-Q27 HydrophobicContact CE1-CG 3.48Å; F23-Q27 VanDerWaalsContact CE1-CG 3.48Å; F23-Q27 HydrophobicContact CE2-CG 4.49Å; F23-Q27 HydrophobicContact CZ-CG 3.81Å; F23-Q27 WeakPolarHBondContact O-CG 3.36Å; F23-Q27 PolarHBondContact O-N 3.05Å; R24-Q27 PolarHBondContact O-N 2.58Å; Q27-K29 PolarHBondContact O-N 3.34Å; Q27-S30 WeakPolarHBondContact O-CB 3.21Å; Q27-S30 PolarHBondContact O-N 2.98Å; Q27-S30 VanDerWaalsContact O-N 3.17Å; Q27-L31 PolarHBondContact O-N 3.2Å; Q27-I127 HydrophobicContact CB-CG2 3.71Å; Q27-L156 HydrophobicContact CB-CD2 4.35Å; Q27-L156 VanDerWaalsContact O-CD2 3.24Å; Q27-L156 WeakPolarHBondContact O-CD2 3.25Å; Q27-Y161 HydrophobicContact CB-CE2 4.39Å; Q27-Y161 HydrophobicContact CG-CE2 3.91Å
28L98.9Very high98.5Very high0 Ų056.5 Ų56.50%027%0.267CS..Hα-helixtrans-59.7-43.9175.9-71.4173.4000112.4R24 V25 S30 L31 Q32 I69 A72 V73 I124 I127 A128R24-L28 WeakPolarHBondContact O-CG 3.19Å; R24-L28 PolarHBondContact O-N 2.8Å; V25-L28 PolarHBondContact O-N 3.41Å; L28-S30 VanDerWaalsContact C-N 3.35Å; L28-S30 PolarHBondContact O-N 3.32Å; L28-L31 WeakPolarHBondContact O-CB 3.12Å; L28-L31 PolarHBondContact O-N 3.46Å; L28-Q32 PolarHBondContact O-N 3.21Å; L28-I69 HydrophobicContact CB-CG2 4.21Å; L28-I69 WeakPolarHBondContact O-CG2 3.45Å; L28-A72 HydrophobicContact CD1-CB 3.98Å; L28-V73 HydrophobicContact CB-CG2 3.85Å; L28-V73 HydrophobicContact CD1-CG2 4.09Å; L28-I124 HydrophobicContact CD2-CB 4.38Å; L28-I124 HydrophobicContact CD2-CG2 3.88Å; L28-I127 HydrophobicContact CD2-CB 4.12Å; L28-I127 HydrophobicContact CD2-CG2 3.94Å; L28-I127 HydrophobicContact CG-CG2 3.84Å; L28-A128 HydrophobicContact CD1-CB 4.39Å
29K98.9Very high98.4Very high121 Ų12160.3 Ų60.353%0.52629%0.285SS..Hα-helixtrans-66.9-34.1175.4-73.6-178176.1-172.80112.8V25 Q26 Q27 Q32 R33 V73V25-K29 HydrophobicContact CG1-CD 4.09Å; V25-K29 HydrophobicContact CG1-CG 4.4Å; V25-K29 WeakPolarHBondContact O-CB 3.39Å; V25-K29 WeakPolarHBondContact O-CG 3.31Å; V25-K29 PolarHBondContact O-N 3.24Å; Q26-K29 PolarHBondContact O-N 3.08Å; Q27-K29 PolarHBondContact O-N 3.34Å; K29-Q32 WeakPolarHBondContact O-CB 3.22Å; K29-Q32 PolarHBondContact O-N 3.16Å; K29-R33 WeakPolarHBondContact O-CG 3.44Å; K29-R33 PolarHBondContact O-N 2.98Å; K29-V73 HydrophobicContact CG-CG2 4.47Å
30S98.9Very high98.3Very high12 Ų1257 Ų578%0.08428%0.282CS..Hα-helixtrans-66.5-37.6171.4-81.10000112.2Q26 Q27 L28 Q32 R33 L34 Y155Q26-S30 PolarHBondContact O-N 3.31Å; Q27-S30 WeakPolarHBondContact O-CB 3.21Å; Q27-S30 PolarHBondContact O-N 2.98Å; Q27-S30 VanDerWaalsContact O-N 3.17Å; L28-S30 VanDerWaalsContact C-N 3.35Å; L28-S30 PolarHBondContact O-N 3.32Å; S30-Q32 VanDerWaalsContact C-N 3.35Å; S30-R33 WeakPolarHBondContact O-CB 3.38Å; S30-R33 PolarHBondContact O-N 2.92Å; S30-R33 PolarHBondContact OG-NH2 3.16Å; S30-L34 PolarHBondContact O-N 3.38Å; S30-Y155 WeakPolarHBondContact CB-O 3.39Å; S30-Y155 WeakPolarHBondContact O-CD1 3.36Å; S30-Y155 PolarHBondContact OG-O 3.42Å
31L98.8Very high98.3Very high0 Ų057.1 Ų57.10%028%0.277CS..Hα-helixtrans-64.8-39.9173.7-17158.3000111.7Q27 L28 R33 L34 I35 I69 L120 I124 I127 L152 L156Q27-L31 PolarHBondContact O-N 3.2Å; L28-L31 WeakPolarHBondContact O-CB 3.12Å; L28-L31 PolarHBondContact O-N 3.46Å; L31-R33 VanDerWaalsContact C-N 3.32Å; L31-R33 PolarHBondContact O-N 2.93Å; L31-L34 HydrophobicContact CD1-CD1 4.47Å; L31-L34 WeakPolarHBondContact O-CB 3.47Å; L31-L34 PolarHBondContact O-N 2.84Å; L31-I35 WeakPolarHBondContact O-CG1 3.41Å; L31-I35 PolarHBondContact O-N 3.25Å; L31-I35 VanDerWaalsContact O-N 3.13Å; L31-I69 HydrophobicContact CB-CD1 4.24Å; L31-I69 HydrophobicContact CD2-CD1 4.26Å; L31-I69 HydrophobicContact CG-CD1 4.05Å; L31-L120 HydrophobicContact CD1-CD1 4.29Å; L31-L120 HydrophobicContact CD1-CD2 4.24Å; L31-I124 HydrophobicContact CD2-CD1 4.38Å; L31-I124 HydrophobicContact CD2-CG1 3.61Å; L31-I127 HydrophobicContact CD2-CD1 4.48Å; L31-L152 HydrophobicContact CD1-CD1 4.09Å; L31-L156 HydrophobicContact CB-CD2 4.17Å; L31-L156 HydrophobicContact CD1-CD1 4.41Å
32Q98.6Very high98.2Very high38 Ų3854.2 Ų54.218%0.17826%0.261CS..Hα-helixtrans-57.7-45.7172.2-176.863.653.100111.2L28 K29 S30 L34 I35 T36 E66 I69L28-Q32 PolarHBondContact O-N 3.21Å; K29-Q32 WeakPolarHBondContact O-CB 3.22Å; K29-Q32 PolarHBondContact O-N 3.16Å; S30-Q32 VanDerWaalsContact C-N 3.35Å; Q32-L34 VanDerWaalsContact C-N 3.34Å; Q32-L34 PolarHBondContact O-N 3.34Å; Q32-I35 PolarHBondContact O-N 3.08Å; Q32-T36 PolarHBondContact NE2-OG1 3.38Å; Q32-T36 PolarHBondContact O-N 2.9Å; Q32-T36 PolarHBondContact O-OG1 3.19Å; Q32-E66 PolarHBondContact NE2-OE1 3.47Å; Q32-E66 VanDerWaalsContact NE2-OE1 3.17Å; Q32-I69 HydrophobicContact CB-CD1 4.23Å; Q32-I69 HydrophobicContact CB-CG2 4.07Å
33R98.7Very high98.1Very high116 Ų11646.3 Ų46.344%0.43823%0.23SC..Hα-helixtrans-60.9-41.2176.2-74.5-168.7-53.8117.91112.4K29 S30 L31 I35 T36 E37 Y155K29-R33 WeakPolarHBondContact O-CG 3.44Å; K29-R33 PolarHBondContact O-N 2.98Å; S30-R33 WeakPolarHBondContact O-CB 3.38Å; S30-R33 PolarHBondContact O-N 2.92Å; S30-R33 PolarHBondContact OG-NH2 3.16Å; L31-R33 VanDerWaalsContact C-N 3.32Å; L31-R33 PolarHBondContact O-N 2.93Å; R33-I35 VanDerWaalsContact C-N 3.32Å; R33-I35 PolarHBondContact O-N 3.39Å; R33-T36 PolarHBondContact O-N 3.13Å; R33-E37 WeakPolarHBondContact CB-OE1 3.46Å; R33-E37 IonicContact NH1-OE1 3.7Å; R33-E37 PolarHBondContact NH1-OE1 3.38Å; R33-E37 WeakPolarHBondContact O-CB 3.37Å; R33-E37 WeakPolarHBondContact O-CG 3.17Å; R33-E37 PolarHBondContact O-N 3.12Å; R33-Y155 HydrophobicContact CB-CD1 4.18Å; R33-Y155 HydrophobicContact CB-CE1 4.12Å
34L98.6Very high98Very high2 Ų249.7 Ų49.71%0.0125%0.248CC..Hα-helixtrans-54.5-51.3174.2-177.1160.2000110.5S30 L31 Q32 R38 I42 W116 L151 L152 Y155S30-L34 PolarHBondContact O-N 3.38Å; L31-L34 HydrophobicContact CD1-CD1 4.47Å; L31-L34 WeakPolarHBondContact O-CB 3.47Å; L31-L34 PolarHBondContact O-N 2.84Å; Q32-L34 VanDerWaalsContact C-N 3.34Å; Q32-L34 PolarHBondContact O-N 3.34Å; L34-R38 WeakPolarHBondContact O-CB 3.36Å; L34-R38 WeakPolarHBondContact O-CG 3.2Å; L34-R38 PolarHBondContact O-N 3.5Å; L34-I42 HydrophobicContact CD2-CD1 4.39Å; L34-W116 HydrophobicContact CD2-CZ3 4.09Å; L34-L151 HydrophobicContact CD1-CB 4.04Å; L34-L151 HydrophobicContact CG-CB 4.42Å; L34-L152 HydrophobicContact CD1-CD1 4.07Å; L34-Y155 HydrophobicContact CB-CD1 3.83Å; L34-Y155 HydrophobicContact CB-CD2 3.84Å; L34-Y155 HydrophobicContact CB-CE1 4.19Å; L34-Y155 HydrophobicContact CB-CE2 4.2Å; L34-Y155 HydrophobicContact CB-CG 3.65Å; L34-Y155 HydrophobicContact CD1-CD2 3.77Å; L34-Y155 HydrophobicContact CD1-CE2 4.47Å; L34-Y155 HydrophobicContact CD1-CG 4.1Å; L34-Y155 HydrophobicContact CG-CD2 3.85Å; L34-Y155 HydrophobicContact CG-CE2 4.14Å; L34-Y155 HydrophobicContact CG-CG 4.17Å
35I97.7Very high98Very high0 Ų049 Ų490%025%0.246CC..Hα-helixtrans-61.4-50.4-177.1-65.7164000110.5L31 Q32 R33 Q39 L62 L65 E66 I69L31-I35 WeakPolarHBondContact O-CG1 3.41Å; L31-I35 PolarHBondContact O-N 3.25Å; L31-I35 VanDerWaalsContact O-N 3.13Å; Q32-I35 PolarHBondContact O-N 3.08Å; R33-I35 VanDerWaalsContact C-N 3.32Å; R33-I35 PolarHBondContact O-N 3.39Å; I35-Q39 WeakPolarHBondContact O-CA 3.36Å; I35-Q39 WeakPolarHBondContact O-CB 3.44Å; I35-Q39 PolarHBondContact O-N 2.92Å; I35-Q39 VanDerWaalsContact O-N 3.09Å; I35-L62 HydrophobicContact CG2-CB 4.17Å; I35-L62 HydrophobicContact CG2-CD2 4.35Å; I35-L65 HydrophobicContact CD1-CB 3.76Å; I35-L65 HydrophobicContact CD1-CD1 4.21Å; I35-E66 HydrophobicContact CG2-CG 3.97Å; I35-I69 HydrophobicContact CD1-CD1 3.7Å
36T96.9Very high97.9Very high76 Ų7647.3 Ų47.347%0.46624%0.236SC..Hα-helixtrans-72-41.2-175.3-51.60000112.7Q32 R33 E66Q32-T36 PolarHBondContact NE2-OG1 3.38Å; Q32-T36 PolarHBondContact O-N 2.9Å; Q32-T36 PolarHBondContact O-OG1 3.19Å; R33-T36 PolarHBondContact O-N 3.13Å; T36-E66 PolarHBondContact OG1-OE1 3.45Å; T36-E66 VanDerWaalsContact OG1-OE1 3.13Å
37E98.2Very high97.8Very high100 Ų10045.7 Ų45.747%0.46723%0.227SC..Hα-helixtrans-73.8-27.4-179.5-65.8171.5-161.900112.6R33 Y155R33-E37 WeakPolarHBondContact CB-OE1 3.46Å; R33-E37 IonicContact NH1-OE1 3.7Å; R33-E37 PolarHBondContact NH1-OE1 3.38Å; R33-E37 WeakPolarHBondContact O-CB 3.37Å; R33-E37 WeakPolarHBondContact O-CG 3.17Å; R33-E37 PolarHBondContact O-N 3.12Å; E37-Y155 WeakPolarHBondContact OE2-CE1 3.32Å; E37-Y155 PolarHBondContact OE2-OH 2.95Å
38R97.7Very high97.7Very high74 Ų7450.4 Ų50.428%0.27925%0.249SC..Hα-helixtrans-113.112-172.9-52.5-67.6173.5-178.6-1.5113.9L34 G40 E41 I42 L151 Y155L34-R38 WeakPolarHBondContact O-CB 3.36Å; L34-R38 WeakPolarHBondContact O-CG 3.2Å; L34-R38 PolarHBondContact O-N 3.5Å; R38-G40 PolarHBondContact O-N 3.34Å; R38-G40 VanDerWaalsContact O-N 3.16Å; R38-E41 WeakPolarHBondContact CD-OE1 3.23Å; R38-E41 IonicContact CZ-OE1 3.72Å; R38-E41 IonicContact NE-OE1 3.14Å; R38-E41 IonicContact NH1-OE1 3.15Å; R38-E41 PolarHBondContact NH1-OE1 3.18Å; R38-E41 PolarHBondContact O-N 3.45Å; R38-I42 HydrophobicContact CB-CD1 4.4Å; R38-I42 WeakPolarHBondContact O-CG1 3Å; R38-I42 PolarHBondContact O-N 3.46Å; R38-L151 HydrophobicContact CB-CD1 3.85Å; R38-L151 HydrophobicContact CG-CD1 3.88Å; R38-L151 HydrophobicContact CG-CD2 4.19Å; R38-Y155 HydrophobicContact CG-CE2 4.35Å; R38-Y155 PolarHBondContact NE-OH 3.21Å
39Q96.1Very high97.7Very high81 Ų8151.1 Ų51.138%0.37925%0.253SS..Hα-helixtrans-51.1-41.6-178.4177.4171.5-5.200113.2I35 I42 A43 L62I35-Q39 WeakPolarHBondContact O-CA 3.36Å; I35-Q39 WeakPolarHBondContact O-CB 3.44Å; I35-Q39 PolarHBondContact O-N 2.92Å; I35-Q39 VanDerWaalsContact O-N 3.09Å; Q39-I42 PolarHBondContact O-N 2.98Å; Q39-A43 WeakPolarHBondContact O-CB 3.35Å; Q39-A43 PolarHBondContact O-N 3.33Å; Q39-L62 HydrophobicContact CB-CD1 4.37Å; Q39-L62 HydrophobicContact CG-CD1 3.71Å
40G96.1Very high97.6Very high48 Ų4845.3 Ų45.350%0.49523%0.228SC..Hα-helixtrans-64-44.7178.300000113.1R38 I42 A43 I44R38-G40 PolarHBondContact O-N 3.34Å; R38-G40 VanDerWaalsContact O-N 3.16Å; G40-I42 VanDerWaalsContact C-N 3.33Å; G40-I42 PolarHBondContact O-N 3.1Å; G40-A43 PolarHBondContact O-N 3.07Å; G40-I44 WeakPolarHBondContact O-CG1 3.39Å; G40-I44 PolarHBondContact O-N 2.92Å; G40-I44 VanDerWaalsContact O-N 3.09Å
41E97.8Very high97.5Very high76 Ų7646.7 Ų46.736%0.35523%0.234SC..Hα-helixtrans-64.9-39.4177.1-63.5176.8-123.400111.1R38 I44 A45 L147R38-E41 WeakPolarHBondContact CD-OE1 3.23Å; R38-E41 IonicContact CZ-OE1 3.72Å; R38-E41 IonicContact NE-OE1 3.14Å; R38-E41 IonicContact NH1-OE1 3.15Å; R38-E41 PolarHBondContact NH1-OE1 3.18Å; R38-E41 PolarHBondContact O-N 3.45Å; E41-I44 PolarHBondContact O-N 3.26Å; E41-A45 PolarHBondContact O-N 3.48Å; E41-L147 HydrophobicContact CB-CD1 4.46Å; E41-L147 HydrophobicContact CB-CD2 3.96Å; E41-L147 WeakPolarHBondContact O-CD2 3.41Å
42I97.8Very high97.2Very high0 Ų047.1 Ų47.10%024%0.236CC..Hα-helixtrans-62.8-44.7176.1-65.8166.6000111.1L34 R38 Q39 G40 I44 A45 L46 L62 W116 L147L34-I42 HydrophobicContact CD2-CD1 4.39Å; R38-I42 HydrophobicContact CB-CD1 4.4Å; R38-I42 WeakPolarHBondContact O-CG1 3Å; R38-I42 PolarHBondContact O-N 3.46Å; Q39-I42 PolarHBondContact O-N 2.98Å; G40-I42 VanDerWaalsContact C-N 3.33Å; G40-I42 PolarHBondContact O-N 3.1Å; I42-I44 VanDerWaalsContact C-N 3.31Å; I42-I44 PolarHBondContact O-N 2.87Å; I42-A45 PolarHBondContact O-N 3.25Å; I42-L46 HydrophobicContact CG2-CD1 3.98Å; I42-L46 PolarHBondContact O-N 3.23Å; I42-L62 HydrophobicContact CG2-CD1 4.46Å; I42-L62 HydrophobicContact CG2-CD2 4.02Å; I42-W116 HydrophobicContact CB-CZ2 4.43Å; I42-W116 HydrophobicContact CD1-CD2 4.47Å; I42-W116 HydrophobicContact CD1-CE3 4.1Å; I42-W116 HydrophobicContact CD1-CH2 4.24Å; I42-W116 HydrophobicContact CD1-CZ3 3.97Å; I42-W116 HydrophobicContact CG1-CD2 4.27Å; I42-W116 HydrophobicContact CG1-CE3 4.25Å; I42-W116 HydrophobicContact CG1-CH2 3.76Å; I42-W116 HydrophobicContact CG1-CZ2 3.77Å; I42-W116 HydrophobicContact CG1-CZ3 4Å; I42-W116 HydrophobicContact CG2-CD2 3.86Å; I42-W116 HydrophobicContact CG2-CG 3.99Å; I42-W116 HydrophobicContact CG2-CZ2 4.28Å; I42-L147 HydrophobicContact CG1-CD2 4.33Å
43A96.7Very high96.7Very high14 Ų1445.7 Ų45.712%0.11623%0.23CC..Hα-helixtrans-62.8-37.6177.200000112.3Q39 G40 L46 K47 T57Q39-A43 WeakPolarHBondContact O-CB 3.35Å; Q39-A43 PolarHBondContact O-N 3.33Å; G40-A43 PolarHBondContact O-N 3.07Å; A43-L46 PolarHBondContact O-N 2.59Å; A43-K47 WeakPolarHBondContact O-CB 3.04Å; A43-K47 PolarHBondContact O-N 3.37Å; A43-T57 HydrophobicContact CB-CG2 4.12Å
44I97.3Very high96Very high105 Ų10545.9 Ų45.954%0.53824%0.236SC..Hα-helixtrans-63.1-48.1174.4-68.4164.5000110.5G40 E41 I42 L46 K47 Q48G40-I44 WeakPolarHBondContact O-CG1 3.39Å; G40-I44 PolarHBondContact O-N 2.92Å; G40-I44 VanDerWaalsContact O-N 3.09Å; E41-I44 PolarHBondContact O-N 3.26Å; I42-I44 VanDerWaalsContact C-N 3.31Å; I42-I44 PolarHBondContact O-N 2.87Å; I44-L46 VanDerWaalsContact C-N 3.34Å; I44-L46 PolarHBondContact O-N 3.5Å; I44-K47 WeakPolarHBondContact O-CB 3.48Å; I44-K47 PolarHBondContact O-N 3.14Å; I44-K47 VanDerWaalsContact O-N 3.16Å; I44-Q48 WeakPolarHBondContact O-CG 3.27Å; I44-Q48 PolarHBondContact O-N 3.26Å
45A97.9Very high95.3Very high4 Ų453.8 Ų53.83%0.03327%0.267CS..Hα-helixtrans-59.5-43.9178.600000112.1E41 I42 K47 Q48 D49 H143 L147E41-A45 PolarHBondContact O-N 3.48Å; I42-A45 PolarHBondContact O-N 3.25Å; A45-K47 VanDerWaalsContact C-N 3.34Å; A45-K47 PolarHBondContact O-N 2.98Å; A45-Q48 PolarHBondContact O-N 3.3Å; A45-Q48 VanDerWaalsContact O-N 3.15Å; A45-D49 PolarHBondContact O-N 3.5Å; A45-H143 HydrophobicContact CB-CB 4.01Å; A45-L147 HydrophobicContact CB-CD2 3.97Å
46L97.5Very high94.6Very high0 Ų055.6 Ų55.60%028%0.277CS..Hα-helixtrans-67.5-32.5176.5-75.8168.9000113.3I42 A43 I44 Q48 L50 T57 E61 P115I42-L46 HydrophobicContact CG2-CD1 3.98Å; I42-L46 PolarHBondContact O-N 3.23Å; A43-L46 PolarHBondContact O-N 2.59Å; I44-L46 VanDerWaalsContact C-N 3.34Å; I44-L46 PolarHBondContact O-N 3.5Å; L46-Q48 VanDerWaalsContact C-N 3.31Å; L46-L50 HydrophobicContact CD2-CD1 4.27Å; L46-L50 PolarHBondContact O-N 3.3Å; L46-T57 HydrophobicContact CD1-CG2 3.44Å; L46-T57 VanDerWaalsContact CD1-CG2 3.44Å; L46-E61 WeakPolarHBondContact CD2-OE1 3.43Å; L46-P115 HydrophobicContact CD2-CG 3.58Å
47K96.5Very high94.1Very high80 Ų8052 Ų5235%0.34826%0.255SS..Hα-helixtrans-64-39.7171.3-172.470.5-177.2171.90110.6A43 I44 A45 N51 R52A43-K47 WeakPolarHBondContact O-CB 3.04Å; A43-K47 PolarHBondContact O-N 3.37Å; I44-K47 WeakPolarHBondContact O-CB 3.48Å; I44-K47 PolarHBondContact O-N 3.14Å; I44-K47 VanDerWaalsContact O-N 3.16Å; A45-K47 VanDerWaalsContact C-N 3.34Å; A45-K47 PolarHBondContact O-N 2.98Å; K47-N51 WeakPolarHBondContact CE-OD1 3.39Å; K47-N51 PolarHBondContact NZ-O 2.97Å; K47-N51 PolarHBondContact NZ-OD1 3.26Å; K47-N51 WeakPolarHBondContact O-CA 3.48Å; K47-N51 PolarHBondContact O-N 2.99Å; K47-R52 WeakPolarHBondContact CD-O 3.44Å
48Q97.4Very high93.6Very high111 Ų11148.1 Ų48.152%0.51924%0.239SC..Hα-helixtrans-71.1-41.4178.2-65.2172.3-58.200112.2I44 A45 L46 H143I44-Q48 WeakPolarHBondContact O-CG 3.27Å; I44-Q48 PolarHBondContact O-N 3.26Å; A45-Q48 PolarHBondContact O-N 3.3Å; A45-Q48 VanDerWaalsContact O-N 3.15Å; L46-Q48 VanDerWaalsContact C-N 3.31Å; Q48-H143 HydrophobicContact CB-CB 4.2Å; Q48-H143 WeakPolarHBondContact CB-CD2 3.29Å; Q48-H143 PolarHBondContact OE1-ND1 3.17Å
49D97.9Very high93Very high15 Ų1550.7 Ų50.78%0.0826%0.258CS..Hα-helixtrans-75.4-40.6-178-68.1-35.8000113.1A45 S141 E142 H143 S144 I284A45-D49 PolarHBondContact O-N 3.5Å; D49-S141 VanDerWaalsContact OD1-C 3.27Å; D49-S141 WeakPolarHBondContact OD1-CA 3.47Å; D49-S141 WeakPolarHBondContact OD2-CB 3.33Å; D49-E142 PolarHBondContact OD1-N 3.36Å; D49-H143 WeakPolarHBondContact OD1-CB 3.47Å; D49-H143 IonicContact OD1-CD2 3.43Å; D49-H143 PolarHBondContact OD1-CD2 3.34Å; D49-H143 IonicContact OD1-CG 2.61Å; D49-H143 PolarHBondContact OD1-N 2.93Å; D49-S144 WeakPolarHBondContact OD2-CB 3.46Å; D49-S144 PolarHBondContact OD2-N 2.79Å; D49-S144 PolarHBondContact OD2-OG 3.46Å; D49-I284 VanDerWaalsContact O-CD1 3.28Å; D49-I284 WeakPolarHBondContact O-CD1 3.32Å
50L97.2Very high92.6Very high0 Ų047.8 Ų47.80%025%0.246CC..Hα-helixtrans-129.81.4-166.7-67.3169.3000113.9L46 R52 W112 N113 G281 R282 I284L46-L50 HydrophobicContact CD2-CD1 4.27Å; L46-L50 PolarHBondContact O-N 3.3Å; L50-R52 HydrophobicContact CB-CB 4.44Å; L50-R52 PolarHBondContact O-N 3.4Å; L50-R52 VanDerWaalsContact O-N 3.17Å; L50-W112 HydrophobicContact CD2-CE3 4.35Å; L50-W112 HydrophobicContact CD2-CZ3 4.41Å; L50-N113 WeakPolarHBondContact CD1-O 3.22Å; L50-G281 WeakPolarHBondContact O-CA 2.97Å; L50-R282 PolarHBondContact O-N 2.77Å; L50-I284 HydrophobicContact CD2-CB 4.36Å; L50-I284 HydrophobicContact CD2-CD1 3.78Å; L50-I284 HydrophobicContact CG-CD1 4.42Å
51N95.8Very high92.4Very high41 Ų4145.6 Ų45.622%0.21922%0.224CC..  trans55.123.3-169-165.848.6000113.8K47 Y280 R282K47-N51 WeakPolarHBondContact CE-OD1 3.39Å; K47-N51 PolarHBondContact NZ-O 2.97Å; K47-N51 PolarHBondContact NZ-OD1 3.26Å; K47-N51 WeakPolarHBondContact O-CA 3.48Å; K47-N51 PolarHBondContact O-N 2.99Å; N51-Y280 PolarHBondContact ND2-O 3.1Å; N51-R282 HydrophobicContact CB-CB 4.03Å; N51-R282 HydrophobicContact CB-CG 3.58Å; N51-R282 PolarHBondContact ND2-NH1 2.92Å
52R92.6Very high92.3Very high8 Ų842.1 Ų42.13%0.0321%0.207CC..  trans-66.7139.7-175.4-169.6171-65.6165.812.1111.9K47 L50 D56 S60 E61 N113 N237K47-R52 WeakPolarHBondContact CD-O 3.44Å; L50-R52 HydrophobicContact CB-CB 4.44Å; L50-R52 PolarHBondContact O-N 3.4Å; L50-R52 VanDerWaalsContact O-N 3.17Å; R52-D56 HydrophobicContact CG-CB 3.95Å; R52-S60 WeakPolarHBondContact CD-OG 3.19Å; R52-S60 PolarHBondContact NH1-OG 3.17Å; R52-E61 IonicContact CZ-OE1 2.88Å; R52-E61 IonicContact NH1-OE1 2.85Å; R52-E61 PolarHBondContact NH1-OE1 2.92Å; R52-E61 IonicContact NH2-OE1 2.81Å; R52-N113 PolarHBondContact NH2-O 3.27Å; R52-N237 PolarHBondContact NH2-ND2 3.43Å; R52-N237 PolarHBondContact NH2-OD1 3.13Å
53S89.3Confident92.2Very high9 Ų945.4 Ų45.46%0.06322%0.224CC..  trans-61145.6173.8-178.30000111.2Y55 D56 T57 D279S53-Y55 PolarHBondContact O-N 2.63Å; S53-D56 PolarHBondContact O-N 2.69Å; S53-T57 PolarHBondContact O-N 2.92Å; S53-T57 PolarHBondContact O-OG1 3.14Å; S53-D279 WeakPolarHBondContact CB-OD1 3.31Å; S53-D279 PolarHBondContact OG-OD1 3.11Å
54Q83.1Confident92.1Very high119 Ų11946.4 Ų46.456%0.55624%0.236SC*.Hα-helixtrans-62.6-32.4177.668.1-178.96.400111.7T57Q54-T57 WeakPolarHBondContact O-CB 3.34Å
55Y84.4Confident92.1Very high168 Ų16841.5 Ų41.566%0.65921%0.211SC*.Hα-helixtrans-75-40.9179-61-68.9000111.2S53 T57S53-Y55 PolarHBondContact O-N 2.63Å; Y55-T57 VanDerWaalsContact C-N 3.26Å; Y55-T57 PolarHBondContact O-N 2.76Å
56D82.8Confident92.1Very high39 Ų3943.6 Ų43.621%0.20922%0.22CC..Hα-helixtrans-65.5-30.1174.8-74.6-19.4000112.6R52 S53 A58 L59 S60R52-D56 HydrophobicContact CG-CB 3.95Å; S53-D56 PolarHBondContact O-N 2.69Å; D56-A58 VanDerWaalsContact C-N 3.34Å; D56-A58 PolarHBondContact O-N 3.22Å; D56-L59 PolarHBondContact O-N 2.67Å; D56-S60 WeakPolarHBondContact O-CB 3.28Å; D56-S60 PolarHBondContact O-N 3.35Å; D56-S60 PolarHBondContact O-OG 2.83Å
57T86.1Confident92Very high1 Ų147.9 Ų47.91%0.00624%0.243CC..Hα-helixtrans-56-47.8-179.5-67.30000111.9A43 L46 S53 Q54 Y55 S60 E61 L62A43-T57 HydrophobicContact CB-CG2 4.12Å; L46-T57 HydrophobicContact CD1-CG2 3.44Å; L46-T57 VanDerWaalsContact CD1-CG2 3.44Å; S53-T57 PolarHBondContact O-N 2.92Å; S53-T57 PolarHBondContact O-OG1 3.14Å; Q54-T57 WeakPolarHBondContact O-CB 3.34Å; Y55-T57 VanDerWaalsContact C-N 3.26Å; Y55-T57 PolarHBondContact O-N 2.76Å; T57-S60 WeakPolarHBondContact CA-OG 3.36Å; T57-S60 PolarHBondContact O-N 3.36Å; T57-S60 PolarHBondContact O-OG 2.97Å; T57-S60 VanDerWaalsContact O-OG 3.12Å; T57-E61 PolarHBondContact O-N 3.07Å; T57-E61 VanDerWaalsContact O-N 3.12Å; T57-L62 HydrophobicContact CG2-CD1 4.06Å; T57-L62 HydrophobicContact CG2-CG 4.29Å
58A86.8Confident92.1Very high17 Ų1744.2 Ų44.214%0.1423%0.227CC..Iπ-helixtrans-65.3-45.2-179.700000111.9D56 L62 I63D56-A58 VanDerWaalsContact C-N 3.34Å; D56-A58 PolarHBondContact O-N 3.22Å; A58-L62 PolarHBondContact O-N 3.11Å; A58-I63 HydrophobicContact CB-CD1 4.33Å; A58-I63 WeakPolarHBondContact O-CG1 3.23Å; A58-I63 PolarHBondContact O-N 2.83Å
59L87.1Confident92.1Very high128 Ų12839 Ų3967%0.6720%0.203SC*.Iπ-helixtrans-67.5-35.4179.8-67.1171.5000112.7D56 I63D56-L59 PolarHBondContact O-N 2.67Å; L59-I63 HydrophobicContact CD2-CD1 4.03Å
60S86.5Confident92.2Very high20 Ų2041.8 Ų41.814%0.1422%0.223CC..Iπ-helixtrans-80.7-38.7-174.159.80000113.8R52 D56 T57 F236R52-S60 WeakPolarHBondContact CD-OG 3.19Å; R52-S60 PolarHBondContact NH1-OG 3.17Å; D56-S60 WeakPolarHBondContact O-CB 3.28Å; D56-S60 PolarHBondContact O-N 3.35Å; D56-S60 PolarHBondContact O-OG 2.83Å; T57-S60 WeakPolarHBondContact CA-OG 3.36Å; T57-S60 PolarHBondContact O-N 3.36Å; T57-S60 PolarHBondContact O-OG 2.97Å; T57-S60 VanDerWaalsContact O-OG 3.12Å; S60-F236 VanDerWaalsContact CB-CZ 3.47Å
61E93.1Very high92.2Very high3 Ų344.3 Ų44.31%0.01424%0.236CC..Iπ-helixtrans-131-40.6-171-65.6-167.9-116.700114.2L46 R52 T57 L65 Y114 W116 A117L46-E61 WeakPolarHBondContact CD2-OE1 3.43Å; R52-E61 IonicContact CZ-OE1 2.88Å; R52-E61 IonicContact NH1-OE1 2.85Å; R52-E61 PolarHBondContact NH1-OE1 2.92Å; R52-E61 IonicContact NH2-OE1 2.81Å; T57-E61 PolarHBondContact O-N 3.07Å; T57-E61 VanDerWaalsContact O-N 3.12Å; E61-L65 WeakPolarHBondContact O-CD1 3.49Å; E61-L65 VanDerWaalsContact O-CG 3.3Å; E61-L65 WeakPolarHBondContact O-CG 3.48Å; E61-Y114 HydrophobicContact CG-CD1 3.71Å; E61-Y114 HydrophobicContact CG-CG 4.37Å; E61-Y114 VanDerWaalsContact OE2-CA 3.26Å; E61-Y114 WeakPolarHBondContact OE2-CA 3.43Å; E61-W116 WeakPolarHBondContact OE2-CA 3.42Å; E61-W116 WeakPolarHBondContact OE2-CB 3.38Å; E61-W116 PolarHBondContact OE2-N 2.83Å; E61-A117 HydrophobicContact CB-CB 4.04Å; E61-A117 HydrophobicContact CG-CB 3.93Å; E61-A117 PolarHBondContact OE2-N 2.76Å
62L95.1Very high92.4Very high2 Ų242.5 Ų42.51%0.0123%0.227CC..Iπ-helixtrans-82.5-49.1-164.7-52.2-174.8000112.9I35 Q39 I42 T57 A58 G64 L65 E66I35-L62 HydrophobicContact CG2-CB 4.17Å; I35-L62 HydrophobicContact CG2-CD2 4.35Å; Q39-L62 HydrophobicContact CB-CD1 4.37Å; Q39-L62 HydrophobicContact CG-CD1 3.71Å; I42-L62 HydrophobicContact CG2-CD1 4.46Å; I42-L62 HydrophobicContact CG2-CD2 4.02Å; T57-L62 HydrophobicContact CG2-CD1 4.06Å; T57-L62 HydrophobicContact CG2-CG 4.29Å; A58-L62 PolarHBondContact O-N 3.11Å; L62-G64 PolarHBondContact O-N 2.85Å; L62-L65 WeakPolarHBondContact O-CA 3.39Å; L62-L65 WeakPolarHBondContact O-CB 3.47Å; L62-L65 PolarHBondContact O-N 2.81Å; L62-E66 WeakPolarHBondContact O-CG 3.46Å; L62-E66 PolarHBondContact O-N 3.46Å
63I94.4Very high92.6Very high69 Ų6944 Ų4435%0.35424%0.237SC..Hα-helixtrans-58.5-37.9-177.4-70.1167.3000111.1A58 L59 L65 E66 N67A58-I63 HydrophobicContact CB-CD1 4.33Å; A58-I63 WeakPolarHBondContact O-CG1 3.23Å; A58-I63 PolarHBondContact O-N 2.83Å; L59-I63 HydrophobicContact CD2-CD1 4.03Å; I63-L65 PolarHBondContact O-N 3.45Å; I63-E66 PolarHBondContact O-N 3.34Å; I63-N67 WeakPolarHBondContact O-CB 3.36Å; I63-N67 VanDerWaalsContact O-CG 3.25Å; I63-N67 PolarHBondContact O-N 3.28Å; I63-N67 PolarHBondContact O-ND2 3Å
64G94.8Very high93.1Very high36 Ų3646.2 Ų46.237%0.37126%0.261SS..Hα-helixtrans-59.8-43.9174.600000112.6L62 N67 E68L62-G64 PolarHBondContact O-N 2.85Å; G64-N67 PolarHBondContact O-N 2.92Å; G64-E68 WeakPolarHBondContact O-CB 3.24Å; G64-E68 PolarHBondContact O-N 3.42Å
65L97.4Very high93.8Very high1 Ų144.9 Ų44.91%0.00525%0.254CS..Hα-helixtrans-65.5-42.6176.8-66.5170.5000112.1I35 E61 L62 I63 N67 E68 I69 L120 Q121 I124I35-L65 HydrophobicContact CD1-CB 3.76Å; I35-L65 HydrophobicContact CD1-CD1 4.21Å; E61-L65 WeakPolarHBondContact O-CD1 3.49Å; E61-L65 VanDerWaalsContact O-CG 3.3Å; E61-L65 WeakPolarHBondContact O-CG 3.48Å; L62-L65 WeakPolarHBondContact O-CA 3.39Å; L62-L65 WeakPolarHBondContact O-CB 3.47Å; L62-L65 PolarHBondContact O-N 2.81Å; I63-L65 PolarHBondContact O-N 3.45Å; L65-N67 VanDerWaalsContact C-N 3.33Å; L65-N67 PolarHBondContact O-N 3.23Å; L65-E68 PolarHBondContact O-N 3.33Å; L65-I69 VanDerWaalsContact O-CG1 3.29Å; L65-I69 WeakPolarHBondContact O-CG1 3.36Å; L65-I69 PolarHBondContact O-N 2.76Å; L65-L120 HydrophobicContact CD1-CB 4.02Å; L65-L120 HydrophobicContact CD1-CD1 4.02Å; L65-L120 HydrophobicContact CD2-CB 3.75Å; L65-Q121 HydrophobicContact CD2-CB 3.79Å; L65-Q121 HydrophobicContact CD2-CG 4.47Å; L65-I124 HydrophobicContact CB-CD1 4.37Å; L65-I124 HydrophobicContact CD2-CD1 3.73Å
66E97.3Very high94.5Very high48 Ų4837 Ų3722%0.22422%0.223CC..Hα-helixtrans-62.8-41.3178.1-58-168.3143.900111.7Q32 I35 T36 L62 I63 I69 S70Q32-E66 PolarHBondContact NE2-OE1 3.47Å; Q32-E66 VanDerWaalsContact NE2-OE1 3.17Å; I35-E66 HydrophobicContact CG2-CG 3.97Å; T36-E66 PolarHBondContact OG1-OE1 3.45Å; T36-E66 VanDerWaalsContact OG1-OE1 3.13Å; L62-E66 WeakPolarHBondContact O-CG 3.46Å; L62-E66 PolarHBondContact O-N 3.46Å; I63-E66 PolarHBondContact O-N 3.34Å; E66-I69 PolarHBondContact O-N 2.7Å; E66-S70 VanDerWaalsContact O-CB 3.31Å; E66-S70 WeakPolarHBondContact O-CB 3.35Å; E66-S70 PolarHBondContact O-N 2.6Å; E66-S70 PolarHBondContact O-OG 3.34Å
67N96.8Very high95.2Very high90 Ų9039 Ų3948%0.48124%0.24SC..Hα-helixtrans-65.9-41.4175.4-72.7-26.3000111.9I63 G64 L65 S70 L71I63-N67 WeakPolarHBondContact O-CB 3.36Å; I63-N67 VanDerWaalsContact O-CG 3.25Å; I63-N67 PolarHBondContact O-N 3.28Å; I63-N67 PolarHBondContact O-ND2 3Å; G64-N67 PolarHBondContact O-N 2.92Å; L65-N67 VanDerWaalsContact C-N 3.33Å; L65-N67 PolarHBondContact O-N 3.23Å; N67-S70 PolarHBondContact O-N 2.83Å; N67-L71 VanDerWaalsContact O-CB 3.29Å; N67-L71 WeakPolarHBondContact O-CB 3.38Å; N67-L71 PolarHBondContact O-N 3.4Å
68E97.7Very high95.8Very high3 Ų344.8 Ų44.81%0.01427%0.267CS..Hα-helixtrans-64.2-43.2177.2-172.280.1152.800111.5G64 L65 L71 A72 Q121 I124 N396 H412 G413G64-E68 WeakPolarHBondContact O-CB 3.24Å; G64-E68 PolarHBondContact O-N 3.42Å; L65-E68 PolarHBondContact O-N 3.33Å; E68-L71 PolarHBondContact O-N 3.47Å; E68-A72 WeakPolarHBondContact O-CB 3.25Å; E68-A72 PolarHBondContact O-N 2.92Å; E68-Q121 HydrophobicContact CG-CG 4.15Å; E68-I124 HydrophobicContact CB-CD1 4.21Å; E68-I124 HydrophobicContact CG-CB 4.39Å; E68-I124 HydrophobicContact CG-CD1 4.19Å; E68-I124 HydrophobicContact CG-CG2 3.82Å; E68-N396 PolarHBondContact OE2-ND2 3Å; E68-H412 WeakPolarHBondContact OE1-CA 3.49Å; E68-G413 VanDerWaalsContact CD-N 3.32Å; E68-G413 PolarHBondContact OE1-N 2.94Å; E68-G413 PolarHBondContact OE2-N 3.15Å
69I98.6Very high96.4Very high3 Ų344.8 Ų44.82%0.01526%0.263CS..Hα-helixtrans-62.3-48.2174.8-69.1164.4000110.5L28 L31 Q32 I35 L65 E66 L71 A72 V73 I124L28-I69 HydrophobicContact CB-CG2 4.21Å; L28-I69 WeakPolarHBondContact O-CG2 3.45Å; L31-I69 HydrophobicContact CB-CD1 4.24Å; L31-I69 HydrophobicContact CD2-CD1 4.26Å; L31-I69 HydrophobicContact CG-CD1 4.05Å; Q32-I69 HydrophobicContact CB-CD1 4.23Å; Q32-I69 HydrophobicContact CB-CG2 4.07Å; I35-I69 HydrophobicContact CD1-CD1 3.7Å; L65-I69 VanDerWaalsContact O-CG1 3.29Å; L65-I69 WeakPolarHBondContact O-CG1 3.36Å; L65-I69 PolarHBondContact O-N 2.76Å; E66-I69 PolarHBondContact O-N 2.7Å; I69-L71 VanDerWaalsContact C-N 3.31Å; I69-L71 PolarHBondContact O-N 3.03Å; I69-A72 PolarHBondContact O-N 3.07Å; I69-V73 HydrophobicContact CG2-CG2 4.24Å; I69-V73 WeakPolarHBondContact O-CB 3.46Å; I69-V73 WeakPolarHBondContact O-CG2 3.36Å; I69-V73 PolarHBondContact O-N 3.1Å; I69-I124 HydrophobicContact CD1-CD1 4.04Å; I69-I124 HydrophobicContact CD1-CG1 4.34Å; I69-I124 HydrophobicContact CG1-CD1 3.52Å; I69-I124 HydrophobicContact CG1-CG1 3.7Å; I69-I124 HydrophobicContact CG1-CG2 4.3Å
70S98.4Very high96.9Very high72 Ų7239.6 Ų39.650%0.50324%0.239SC..Hα-helixtrans-60.2-43.1-179.9-64.60000111.5E66 N67 G74E66-S70 VanDerWaalsContact O-CB 3.31Å; E66-S70 WeakPolarHBondContact O-CB 3.35Å; E66-S70 PolarHBondContact O-N 2.6Å; E66-S70 PolarHBondContact O-OG 3.34Å; N67-S70 PolarHBondContact O-N 2.83Å; S70-G74 PolarHBondContact O-N 2.91Å
71L98.5Very high97.5Very high53 Ų5340.6 Ų40.628%0.27725%0.248SC..Hα-helixtrans-61.1-50174.4176.864.3000111.3N67 E68 I69 V73 G74 K75 W79 N396N67-L71 VanDerWaalsContact O-CB 3.29Å; N67-L71 WeakPolarHBondContact O-CB 3.38Å; N67-L71 PolarHBondContact O-N 3.4Å; E68-L71 PolarHBondContact O-N 3.47Å; I69-L71 VanDerWaalsContact C-N 3.31Å; I69-L71 PolarHBondContact O-N 3.03Å; L71-V73 PolarHBondContact O-N 2.73Å; L71-G74 PolarHBondContact O-N 2.97Å; L71-K75 HydrophobicContact CD1-CG 3.78Å; L71-K75 WeakPolarHBondContact O-CB 3.43Å; L71-K75 WeakPolarHBondContact O-CG 3.15Å; L71-K75 PolarHBondContact O-N 2.84Å; L71-W79 HydrophobicContact CD1-CZ2 4.45Å; L71-W79 HydrophobicContact CD2-CH2 4.33Å; L71-W79 HydrophobicContact CD2-CZ2 4.4Å; L71-W79 HydrophobicContact CG-CH2 3.99Å; L71-W79 HydrophobicContact CG-CZ2 4.06Å; L71-N396 HydrophobicContact CD2-CB 3.46Å; L71-N396 VanDerWaalsContact CD2-CB 3.46Å
72A98.6Very high97.7Very high3 Ų343.8 Ų43.83%0.02527%0.269CS..Hα-helixtrans-59.2-49.4179.600000111L28 E68 I69 G74 K75 L76 W79 I124 A128L28-A72 HydrophobicContact CD1-CB 3.98Å; E68-A72 WeakPolarHBondContact O-CB 3.25Å; E68-A72 PolarHBondContact O-N 2.92Å; I69-A72 PolarHBondContact O-N 3.07Å; A72-G74 VanDerWaalsContact C-N 3.32Å; A72-G74 PolarHBondContact O-N 2.93Å; A72-K75 PolarHBondContact O-N 2.89Å; A72-L76 WeakPolarHBondContact O-CA 3.13Å; A72-L76 WeakPolarHBondContact O-CB 3.44Å; A72-L76 PolarHBondContact O-N 3.39Å; A72-W79 HydrophobicContact CB-CH2 4.39Å; A72-W79 HydrophobicContact CB-CZ3 3.98Å; A72-I124 HydrophobicContact CB-CG2 4.22Å; A72-A128 HydrophobicContact CB-CB 4.43Å
73V98.8Very high97.9Very high41 Ų4146.8 Ų46.825%0.24828%0.28CS..Hα-helixtrans-58.2-43.6176.9170.20000111.6V25 L28 K29 I69 L71 K75V25-V73 HydrophobicContact CG1-CG1 4.14Å; V25-V73 HydrophobicContact CG1-CG2 4.49Å; L28-V73 HydrophobicContact CB-CG2 3.85Å; L28-V73 HydrophobicContact CD1-CG2 4.09Å; K29-V73 HydrophobicContact CG-CG2 4.47Å; I69-V73 HydrophobicContact CG2-CG2 4.24Å; I69-V73 WeakPolarHBondContact O-CB 3.46Å; I69-V73 WeakPolarHBondContact O-CG2 3.36Å; I69-V73 PolarHBondContact O-N 3.1Å; L71-V73 PolarHBondContact O-N 2.73Å; V73-K75 VanDerWaalsContact C-N 3.35Å; V73-K75 PolarHBondContact O-N 2.81Å
74G98.5Very high97.9Very high55 Ų5550.5 Ų50.557%0.56730%0.296SS*.Hα-helixtrans-71.7-23.7-17900000114.8S70 L71 A72S70-G74 PolarHBondContact O-N 2.91Å; L71-G74 PolarHBondContact O-N 2.97Å; A72-G74 VanDerWaalsContact C-N 3.32Å; A72-G74 PolarHBondContact O-N 2.93Å
75K98.6Very high97.8Very high90 Ų9051.5 Ų51.539%0.39130%0.295SS..Hα-helixtrans-116.3-8.2-173.6-63.7-63.5-171.7179.60115L71 A72 V73 S77 Q78 W79L71-K75 HydrophobicContact CD1-CG 3.78Å; L71-K75 WeakPolarHBondContact O-CB 3.43Å; L71-K75 WeakPolarHBondContact O-CG 3.15Å; L71-K75 PolarHBondContact O-N 2.84Å; A72-K75 PolarHBondContact O-N 2.89Å; V73-K75 VanDerWaalsContact C-N 3.35Å; V73-K75 PolarHBondContact O-N 2.81Å; K75-S77 VanDerWaalsContact C-N 3.32Å; K75-S77 PolarHBondContact O-N 3.22Å; K75-Q78 WeakPolarHBondContact O-CA 3.48Å; K75-Q78 WeakPolarHBondContact O-CB 3.39Å; K75-Q78 PolarHBondContact O-N 3.33Å; K75-W79 HydrophobicContact CB-CD2 3.92Å; K75-W79 HydrophobicContact CB-CG 4.32Å; K75-W79 HydrophobicContact CB-CH2 4.29Å; K75-W79 HydrophobicContact CB-CZ2 3.58Å; K75-W79 HydrophobicContact CG-CZ2 4.14Å; K75-W79 PolarHBondContact O-N 3.23Å
76L98.5Very high97.5Very high2 Ų260.5 Ų60.51%0.0134%0.337CS..Hα-helixtrans-56.2-42-171.8177.360.3000113.5L21 R24 V25 A72 Q78 W79 A80 A128 F417L21-L76 HydrophobicContact CB-CD2 4.49Å; L21-L76 HydrophobicContact CD2-CD1 4.37Å; L21-L76 HydrophobicContact CD2-CD2 4.35Å; L21-L76 HydrophobicContact CD2-CG 4.12Å; R24-L76 HydrophobicContact CB-CD2 3.81Å; V25-L76 HydrophobicContact CG2-CD2 3.87Å; A72-L76 WeakPolarHBondContact O-CA 3.13Å; A72-L76 WeakPolarHBondContact O-CB 3.44Å; A72-L76 PolarHBondContact O-N 3.39Å; L76-Q78 VanDerWaalsContact C-N 3.31Å; L76-Q78 PolarHBondContact O-N 2.99Å; L76-W79 PolarHBondContact O-N 3.48Å; L76-A80 WeakPolarHBondContact O-CB 3.33Å; L76-A80 PolarHBondContact O-N 3.23Å; L76-A128 HydrophobicContact CD1-CB 4.21Å; L76-A128 WeakPolarHBondContact CD1-O 3.41Å; L76-F417 HydrophobicContact CD1-CD2 4.24Å; L76-F417 HydrophobicContact CD1-CE2 3.86Å
77S98.4Very high97.1Very high81 Ų8162.7 Ų62.757%0.56635%0.346SS*.Hα-helixtrans-61-40.6177.4570000112.3K75 A81K75-S77 VanDerWaalsContact C-N 3.32Å; K75-S77 PolarHBondContact O-N 3.22Å; S77-A81 PolarHBondContact O-N 2.96Å
78Q98.6Very high96.5Very high124 Ų12461.1 Ų61.158%0.57934%0.338SS*.Hα-helixtrans-67.8-42.4175.1-176.7-174.91.300111.3K75 L76 A81K75-Q78 WeakPolarHBondContact O-CA 3.48Å; K75-Q78 WeakPolarHBondContact O-CB 3.39Å; K75-Q78 PolarHBondContact O-N 3.33Å; L76-Q78 VanDerWaalsContact C-N 3.31Å; L76-Q78 PolarHBondContact O-N 2.99Å; Q78-A81 PolarHBondContact O-N 3.13Å
79W98.6Very high95.7Very high16 Ų1665.1 Ų65.16%0.06136%0.358CS..Hα-helixtrans-66.8-38-177.4-67-10.1000113L71 A72 K75 L76 R83 K414 F417L71-W79 HydrophobicContact CD1-CZ2 4.45Å; L71-W79 HydrophobicContact CD2-CH2 4.33Å; L71-W79 HydrophobicContact CD2-CZ2 4.4Å; L71-W79 HydrophobicContact CG-CH2 3.99Å; L71-W79 HydrophobicContact CG-CZ2 4.06Å; A72-W79 HydrophobicContact CB-CH2 4.39Å; A72-W79 HydrophobicContact CB-CZ3 3.98Å; K75-W79 HydrophobicContact CB-CD2 3.92Å; K75-W79 HydrophobicContact CB-CG 4.32Å; K75-W79 HydrophobicContact CB-CH2 4.29Å; K75-W79 HydrophobicContact CB-CZ2 3.58Å; K75-W79 HydrophobicContact CG-CZ2 4.14Å; K75-W79 PolarHBondContact O-N 3.23Å; L76-W79 PolarHBondContact O-N 3.48Å; W79-R83 PolarHBondContact O-NH2 2.96Å; W79-R83 VanDerWaalsContact O-NH2 3.1Å; W79-K414 HydrophobicContact CD2-CB 4.39Å; W79-K414 HydrophobicContact CD2-CG 4.27Å; W79-K414 HydrophobicContact CG-CG 4.23Å; W79-K414 HydrophobicContact CZ2-CB 3.84Å; W79-F417 HydrophobicContact CB-CD1 3.86Å; W79-F417 HydrophobicContact CB-CD2 4.2Å; W79-F417 HydrophobicContact CB-CE1 3.84Å; W79-F417 HydrophobicContact CB-CE2 4.16Å; W79-F417 HydrophobicContact CB-CG 4.06Å; W79-F417 HydrophobicContact CB-CZ 4Å; W79-F417 HydrophobicContact CD2-CB 4.45Å; W79-F417 HydrophobicContact CD2-CG 4.45Å; W79-F417 HydrophobicContact CE3-CB 3.8Å; W79-F417 HydrophobicContact CE3-CD2 4.04Å; W79-F417 AromaticContact CE3-CG 3.95Å; W79-F417 HydrophobicContact CE3-CG 3.95Å; W79-F417 HydrophobicContact CZ3-CB 4.23Å; W79-F417 VanDerWaalsContact O-CE1 3.24Å; W79-F417 WeakPolarHBondContact O-CE1 3.22Å
80A98.6Very high94.8Very high20 Ų2070.5 Ų70.517%0.16539%0.385CS..Hα-helixtrans-82.9-10.5-179.900000114.4L21 L76 F417L21-A80 HydrophobicContact CD1-CB 4.26Å; L21-A80 HydrophobicContact CD2-CB 3.68Å; L76-A80 WeakPolarHBondContact O-CB 3.33Å; L76-A80 PolarHBondContact O-N 3.23Å; A80-F417 HydrophobicContact CB-CZ 4.14Å
81A98.4Very high94.3Very high40 Ų4068.2 Ų68.233%0.33137%0.367SS..SBendtrans-67.1149.2179.400000112.3S77 Q78 R83S77-A81 PolarHBondContact O-N 2.96Å; Q78-A81 PolarHBondContact O-N 3.13Å; A81-R83 PolarHBondContact O-N 3.36Å
82P98.1Very high93.7Very high70 Ų7069.9 Ų69.946%0.45538%0.376SS..  trans-54.7135.3169-23.432.3000112Y97 L99P82-Y97 HydrophobicContact CB-CD2 3.83Å; P82-Y97 HydrophobicContact CB-CE2 4.45Å; P82-Y97 HydrophobicContact CB-CG 4.21Å; P82-L99 HydrophobicContact CG-CD1 4.08Å
83R97.6Very high93.3Very high65 Ų6574.3 Ų74.325%0.24540%0.403CS..EExtended strand (participates in β ladder)trans-106.6105.1-179.5-53.1175.3-170.3174.82.7109W79 A81 Y97 I98 D418 H423W79-R83 PolarHBondContact O-NH2 2.96Å; W79-R83 VanDerWaalsContact O-NH2 3.1Å; A81-R83 PolarHBondContact O-N 3.36Å; R83-Y97 CarbonylContact O-C 3.59Å; R83-Y97 VanDerWaalsContact O-CA 3.23Å; R83-Y97 WeakPolarHBondContact O-CA 3.48Å; R83-I98 HydrophobicContact CB-CB 4.32Å; R83-I98 PolarHBondContact N-O 3.26Å; R83-I98 PolarHBondContact O-N 2.86Å; R83-D418 IonicContact CZ-OD1 2.66Å; R83-D418 IonicContact NH1-OD1 3.16Å; R83-D418 PolarHBondContact NH1-OD1 3.36Å; R83-D418 IonicContact NH1-OD2 3.83Å; R83-D418 IonicContact NH2-OD1 3.72Å; R83-D418 PolarHBondContact NH2-OD1 3.19Å; R83-H423 VanDerWaalsContact CZ-CE1 3.41Å; R83-H423 PolarHBondContact NH1-CE1 3.29Å; R83-H423 PolarHBondContact NH2-CE1 3.49Å
84H94.5Very high92.9Very high147 Ų14772.6 Ų72.668%0.68139%0.392SS*.EExtended strand (participates in β ladder)trans-67.4137.6176.2-72.2-70.7000111.2V96H84-V96 PolarHBondContact ND1-O 2.95Å; H84-V96 VanDerWaalsContact ND1-O 3.11Å
85V93.7Very high92.8Very high58 Ų5875.6 Ų75.635%0.35239%0.392SS..  trans-114.6166.1-178.7-62.80000111.1V96 I98V85-V96 HydrophobicContact CG2-CB 4.07Å; V85-V96 HydrophobicContact CG2-CG1 3.41Å; V85-V96 VanDerWaalsContact CG2-CG1 3.41Å; V85-I98 HydrophobicContact CG1-CD1 3.59Å; V85-I98 HydrophobicContact CG1-CG1 3.84Å
86E91.9Very high92.7Very high189 Ų18972.3 Ų72.388%0.88338%0.379SS*.  trans-62143.1172.9-63.6-171.5160.800111
87K88.9Confident92.7Very high94 Ų9474.5 Ų74.541%0.40939%0.388SS..  trans-110.8155.4-179.7-55.5-178.7-168.5179.40108.6T91 L92 D94 V96K87-T91 WeakPolarHBondContact CD-O 3.16Å; K87-L92 WeakPolarHBondContact CD-O 3.31Å; K87-L92 PolarHBondContact NZ-O 2.68Å; K87-D94 WeakPolarHBondContact CE-O 3.23Å; K87-D94 PolarHBondContact NZ-O 3.41Å; K87-V96 HydrophobicContact CD-CG2 4.1Å; K87-V96 HydrophobicContact CG-CB 4.26Å; K87-V96 HydrophobicContact CG-CG2 3.87Å
88N83.3Confident92.7Very high58 Ų5873.1 Ų73.131%0.3137%0.373SS..  trans-105177169.463.946.4000110M90 T91 L92N88-M90 PolarHBondContact O-N 3.44Å; N88-M90 VanDerWaalsContact O-N 3.14Å; N88-M90 WeakPolarHBondContact OD1-CA 3.29Å; N88-M90 WeakPolarHBondContact OD1-CB 3.4Å; N88-M90 PolarHBondContact OD1-N 3.48Å; N88-T91 PolarHBondContact N-OG1 3.25Å; N88-T91 CarbonylContact O-C 3.51Å; N88-T91 PolarHBondContact O-N 2.94Å; N88-T91 PolarHBondContact O-OG1 2.85Å; N88-T91 PolarHBondContact OD1-N 2.9Å; N88-T91 PolarHBondContact OD1-OG1 3.35Å; N88-L92 PolarHBondContact O-N 3.39Å
89I81Confident92.7Very high86 Ų8669.3 Ų69.344%0.44136%0.357SS..THydrogen-bonded Turntrans-58.5-29.8-176.8-157.8165.5000113.1T91I89-T91 VanDerWaalsContact C-N 3.3Å; I89-T91 PolarHBondContact O-N 3.21Å
90M80.1Confident92.7Very high117 Ų11769.2 Ų69.258%0.57636%0.358SS*.THydrogen-bonded Turntrans-77.3-18.5179.5-58.5-176.2-72.500112.8N88N88-M90 PolarHBondContact O-N 3.44Å; N88-M90 VanDerWaalsContact O-N 3.14Å; N88-M90 WeakPolarHBondContact OD1-CA 3.29Å; N88-M90 WeakPolarHBondContact OD1-CB 3.4Å; N88-M90 PolarHBondContact OD1-N 3.48Å
91T87.9Confident92.7Very high23 Ų2370.8 Ų70.814%0.14136%0.362CS..THydrogen-bonded Turntrans-119.57.9-176.460.60000113.8K87 N88 I89 T93 D94 L427K87-T91 WeakPolarHBondContact CD-O 3.16Å; N88-T91 PolarHBondContact N-OG1 3.25Å; N88-T91 CarbonylContact O-C 3.51Å; N88-T91 PolarHBondContact O-N 2.94Å; N88-T91 PolarHBondContact O-OG1 2.85Å; N88-T91 PolarHBondContact OD1-N 2.9Å; N88-T91 PolarHBondContact OD1-OG1 3.35Å; I89-T91 VanDerWaalsContact C-N 3.3Å; I89-T91 PolarHBondContact O-N 3.21Å; T91-T93 VanDerWaalsContact C-N 3.26Å; T91-T93 PolarHBondContact O-N 3.2Å; T91-T93 VanDerWaalsContact O-N 3.14Å; T91-D94 VanDerWaalsContact CA-OD2 3.28Å; T91-D94 WeakPolarHBondContact CA-OD2 3.34Å; T91-D94 WeakPolarHBondContact O-CB 3.44Å; T91-D94 PolarHBondContact O-N 2.8Å; T91-L427 HydrophobicContact CG2-CD1 4.04Å; T91-L427 HydrophobicContact CG2-CD2 4.36Å
92L86.1Confident92.7Very high89 Ų8970.1 Ų70.147%0.46636%0.355SS..THydrogen-bonded Turntrans-54.1-40.9-170.7-171.564.2000113.4K87 N88K87-L92 WeakPolarHBondContact CD-O 3.31Å; K87-L92 PolarHBondContact NZ-O 2.68Å; N88-L92 PolarHBondContact O-N 3.39Å
93T88.6Confident92.7Very high96 Ų9668.9 Ų68.959%0.58934%0.344SS*.THydrogen-bonded Turntrans-86.4-9.3179.857.30000114.1T91 M433T91-T93 VanDerWaalsContact C-N 3.26Å; T91-T93 PolarHBondContact O-N 3.2Å; T91-T93 VanDerWaalsContact O-N 3.14Å; T93-M433 HydrophobicContact CG2-CE 3.82Å; T93-M433 HydrophobicContact CG2-SD 4.43Å; T93-M433 WeakPolarHBondContact OG1-CE 3.41Å
94D91.8Very high92.8Very high4 Ų465.8 Ų65.82%0.02133%0.332CS..SBendtrans-84.3156.4-176.1-56.8-34.9000111K87 T91 V96 L427 K429K87-D94 WeakPolarHBondContact CE-O 3.23Å; K87-D94 PolarHBondContact NZ-O 3.41Å; T91-D94 VanDerWaalsContact CA-OD2 3.28Å; T91-D94 WeakPolarHBondContact CA-OD2 3.34Å; T91-D94 WeakPolarHBondContact O-CB 3.44Å; T91-D94 PolarHBondContact O-N 2.8Å; D94-V96 HydrophobicContact CB-CG2 4.36Å; D94-L427 HydrophobicContact CB-CD1 3.54Å; D94-K429 HydrophobicContact CB-CG 4.47Å; D94-K429 IonicContact OD1-NZ 3.47Å; D94-K429 PolarHBondContact OD1-NZ 3.41Å; D94-K429 IonicContact OD2-NZ 2.92Å; D94-K429 PolarHBondContact OD2-NZ 2.92Å
95Q95.2Very high93Very high119 Ų11958.8 Ų58.856%0.55630%0.3SS*.EExtended strand (participates in β ladder)trans-82.3125.9166.9-54.7-177.3-1.500109L427 I428Q95-L427 CarbonylContact O-C 3.49Å; Q95-L427 WeakPolarHBondContact O-CA 3.39Å; Q95-I428 HydrophobicContact CB-CB 4.06Å; Q95-I428 HydrophobicContact CB-CG1 4.34Å; Q95-I428 PolarHBondContact N-O 2.84Å; Q95-I428 PolarHBondContact O-N 2.79Å
96V96.8Very high93.3Very high21 Ų2156 Ų5613%0.12728%0.283CS..EExtended strand (participates in β ladder)trans-130.6124.2-179.5-161.50000109H84 V85 K87 D94 C426 L427H84-V96 PolarHBondContact ND1-O 2.95Å; H84-V96 VanDerWaalsContact ND1-O 3.11Å; V85-V96 HydrophobicContact CG2-CB 4.07Å; V85-V96 HydrophobicContact CG2-CG1 3.41Å; V85-V96 VanDerWaalsContact CG2-CG1 3.41Å; K87-V96 HydrophobicContact CD-CG2 4.1Å; K87-V96 HydrophobicContact CG-CB 4.26Å; K87-V96 HydrophobicContact CG-CG2 3.87Å; D94-V96 HydrophobicContact CB-CG2 4.36Å; V96-C426 WeakPolarHBondContact CA-O 3.33Å; V96-L427 HydrophobicContact CG2-CD1 3.65Å
97Y97.9Very high93.6Very high48 Ų4847 Ų4719%0.18824%0.241CC..EExtended strand (participates in β ladder)trans-157.4162.2178.359.5-88.9000111.6P82 R83 L99 C426 I428P82-Y97 HydrophobicContact CB-CD2 3.83Å; P82-Y97 HydrophobicContact CB-CE2 4.45Å; P82-Y97 HydrophobicContact CB-CG 4.21Å; R83-Y97 CarbonylContact O-C 3.59Å; R83-Y97 VanDerWaalsContact O-CA 3.23Å; R83-Y97 WeakPolarHBondContact O-CA 3.48Å; Y97-L99 HydrophobicContact CD2-CB 4.22Å; Y97-L99 HydrophobicContact CE2-CB 4.06Å; Y97-C426 HydrophobicContact CD1-CB 4.19Å; Y97-C426 HydrophobicContact CD2-CB 3.83Å; Y97-C426 HydrophobicContact CE1-CB 3.85Å; Y97-C426 HydrophobicContact CE2-CB 3.46Å; Y97-C426 VanDerWaalsContact CE2-CB 3.46Å; Y97-C426 HydrophobicContact CG-CB 4.18Å; Y97-C426 VanDerWaalsContact CZ-CB 3.47Å; Y97-C426 PolarHBondContact N-O 3.32Å; Y97-C426 VanDerWaalsContact N-O 3.07Å; Y97-C426 PolarHBondContact O-N 3.4Å; Y97-I428 HydrophobicContact CE1-CG1 4.11Å
98I98.7Very high94.1Very high51 Ų5142.6 Ų42.626%0.26222%0.222SC..EExtended strand (participates in β ladder)trans-104.5127169.4-63.5169000107.8R83 V85 H423 R424R83-I98 HydrophobicContact CB-CB 4.32Å; R83-I98 PolarHBondContact N-O 3.26Å; R83-I98 PolarHBondContact O-N 2.86Å; V85-I98 HydrophobicContact CG1-CD1 3.59Å; V85-I98 HydrophobicContact CG1-CG1 3.84Å; I98-H423 HydrophobicContact CG2-CB 3.59Å; I98-R424 CarbonylContact C-O 3.59Å; I98-R424 WeakPolarHBondContact CA-O 3.36Å
99L98.4Very high94.8Very high44 Ų4440.2 Ų40.223%0.2321%0.209CC..EExtended strand (participates in β ladder)trans-109.9115.9176.8-177.166.3000110.2P82 Y97 R424P82-L99 HydrophobicContact CG-CD1 4.08Å; Y97-L99 HydrophobicContact CD2-CB 4.22Å; Y97-L99 HydrophobicContact CE2-CB 4.06Å; L99-R424 PolarHBondContact N-O 2.9Å; L99-R424 WeakPolarHBondContact O-CB 3.48Å; L99-R424 PolarHBondContact O-N 3.28Å
100P98.7Very high95.6Very high15 Ų1536.4 Ų36.410%0.09719%0.19CC..EExtended strand (participates in β ladder)trans-67.7130.5170-16.831.4000111.2F417 H422P100-F417 HydrophobicContact CB-CE1 3.8Å; P100-F417 HydrophobicContact CB-CZ 4.02Å; P100-F417 HydrophobicContact CG-CE1 4.19Å; P100-H422 CarbonylContact C-O 3.49Å; P100-H422 WeakPolarHBondContact CA-O 3.39Å
101E98.4Very high96.5Very high53 Ų5331.1 Ų31.125%0.24817%0.166CC..EExtended strand (participates in β ladder)trans-133.6148.6174.765.6-170.9178.300110.6S421 H422 R424E101-S421 CarbonylContact O-C 3.53Å; E101-S421 VanDerWaalsContact O-CA 3.31Å; E101-S421 WeakPolarHBondContact O-CA 3.06Å; E101-H422 HydrophobicContact CG-CB 3.89Å; E101-H422 PolarHBondContact N-O 2.86Å; E101-H422 PolarHBondContact O-N 3.32Å; E101-H422 IonicContact OE1-CE1 3.99Å; E101-H422 IonicContact OE1-CG 2.76Å; E101-H422 IonicContact OE1-ND1 3.65Å; E101-H422 PolarHBondContact OE1-ND1 3.39Å; E101-R424 WeakPolarHBondContact OE1-CD 3.39Å; E101-R424 IonicContact OE1-NH1 3.06Å; E101-R424 IonicContact OE2-CZ 3.46Å; E101-R424 IonicContact OE2-NE 2.63Å; E101-R424 PolarHBondContact OE2-NE 3.45Å; E101-R424 IonicContact OE2-NH1 3.8Å; E101-R424 PolarHBondContact OE2-NH1 3.11Å; E101-R424 IonicContact OE2-NH2 3.16Å
102P98.8Very high97Very high26 Ų2631.4 Ų31.417%0.16916%0.164CC..EExtended strand (participates in β ladder)trans-61.1147.8177.425.8-34.1000111.1F13 A129 N131F13-P102 HydrophobicContact CE2-CB 3.89Å; F13-P102 HydrophobicContact CE2-CG 3.92Å; F13-P102 HydrophobicContact CZ-CB 4.21Å; F13-P102 HydrophobicContact CZ-CG 4.03Å; P102-A129 WeakPolarHBondContact CB-O 3.26Å; P102-N131 WeakPolarHBondContact CB-OD1 3.31Å
103L98.9Very high97.6Very high44 Ų4427.4 Ų27.423%0.2314%0.143CC..  trans-73.2-42.4175.3-63.3174.8000111.7N131 D180 H181 H422L103-N131 PolarHBondContact N-OD1 3.33Å; L103-D180 HydrophobicContact CB-CB 4.03Å; L103-D180 WeakPolarHBondContact O-CB 3.4Å; L103-H181 HydrophobicContact CD1-CB 3.78Å; L103-H422 HydrophobicContact CD2-CB 3.86Å
104G98.9Very high98.1Very high0 Ų023.9 Ų23.90%012%0.119CC..SBendtrans144.2-116.3-175.300000112.8N131 A132 D180G104-N131 PolarHBondContact N-OD1 3.09Å; G104-N131 WeakPolarHBondContact O-CA 3.48Å; G104-N131 VanDerWaalsContact O-CB 3.32Å; G104-N131 WeakPolarHBondContact O-CB 3.4Å; G104-A132 PolarHBondContact O-N 3.04Å; G104-D180 WeakPolarHBondContact CA-OD2 3.49Å
105V98.9Very high98.4Very high0 Ų023.9 Ų23.90%012%0.12CC..EExtended strand (participates in β ladder)trans-101.9119.2175.1-169.70000109.7A9 R10 A132 V134 F179 D180A9-V105 HydrophobicContact CB-CG1 4.19Å; R10-V105 HydrophobicContact CB-CG2 3.86Å; R10-V105 HydrophobicContact CG-CG2 4.22Å; V105-A132 WeakPolarHBondContact CA-O 3.35Å; V105-A132 HydrophobicContact CG1-CB 4.45Å; V105-A132 HydrophobicContact CG2-CB 4.28Å; V105-V134 HydrophobicContact CG1-CG2 4.13Å; V105-F179 HydrophobicContact CB-CD1 4.33Å; V105-F179 HydrophobicContact CG1-CD1 3.87Å; V105-F179 HydrophobicContact CG1-CE1 4.01Å; V105-D180 PolarHBondContact N-OD2 3.46Å; V105-D180 PolarHBondContact O-N 3.46Å
106V98.9Very high98.5Very high0 Ų018.3 Ų18.30%09%0.093CC..EExtended strand (participates in β ladder)trans-96.3133.9177.1-179.10000109.7I108 A126 N131 A132 A133 V134 H181 L420V106-I108 HydrophobicContact CG1-CG1 3.98Å; V106-A126 HydrophobicContact CG2-CB 4.5Å; V106-N131 HydrophobicContact CG2-CB 3.74Å; V106-A132 PolarHBondContact N-O 2.85Å; V106-A133 HydrophobicContact CB-CB 4.41Å; V106-A133 CarbonylContact O-C 3.52Å; V106-A133 WeakPolarHBondContact O-CA 3.4Å; V106-V134 PolarHBondContact O-N 2.95Å; V106-H181 WeakPolarHBondContact CA-O 3.47Å; V106-H181 HydrophobicContact CG1-CB 4.27Å; V106-H181 HydrophobicContact CG2-CB 4.12Å; V106-L420 HydrophobicContact CG1-CD2 4.15Å; V106-L420 HydrophobicContact CG2-CD2 4.29Å
107L98.9Very high98.6Very high0 Ų017.5 Ų17.50%09%0.089CC..EExtended strand (participates in β ladder)trans-92.3129.2165.3175.558.4000109.3I109 V134 K136 L174 L175 F179 H181 I182 F183L107-I109 HydrophobicContact CD1-CG1 4.24Å; L107-I109 HydrophobicContact CD2-CD1 3.92Å; L107-I109 HydrophobicContact CD2-CG1 4.08Å; L107-I109 HydrophobicContact CG-CD1 4.31Å; L107-I109 HydrophobicContact CG-CG1 3.94Å; L107-V134 HydrophobicContact CD1-CB 4.32Å; L107-V134 HydrophobicContact CD1-CG1 4.38Å; L107-K136 HydrophobicContact CD1-CB 4.47Å; L107-L174 HydrophobicContact CD1-CD2 3.39Å; L107-L174 HydrophobicContact CD1-CG 3.94Å; L107-L174 HydrophobicContact CD2-CD2 4.36Å; L107-L174 HydrophobicContact CD2-CG 4.27Å; L107-L175 HydrophobicContact CD2-CD2 3.92Å; L107-F179 HydrophobicContact CB-CB 4.43Å; L107-F179 HydrophobicContact CB-CD1 3.68Å; L107-F179 HydrophobicContact CB-CD2 3.85Å; L107-F179 HydrophobicContact CB-CE1 3.77Å; L107-F179 HydrophobicContact CB-CE2 3.93Å; L107-F179 HydrophobicContact CB-CG 3.71Å; L107-F179 HydrophobicContact CB-CZ 3.88Å; L107-F179 HydrophobicContact CD1-CE1 4.42Å; L107-F179 HydrophobicContact CD1-CE2 4.45Å; L107-F179 HydrophobicContact CD1-CZ 4.05Å; L107-F179 HydrophobicContact CD2-CD2 4.03Å; L107-F179 HydrophobicContact CD2-CE2 3.7Å; L107-F179 HydrophobicContact CD2-CZ 4.14Å; L107-F179 HydrophobicContact CG-CE2 4.23Å; L107-F179 HydrophobicContact CG-CZ 4.23Å; L107-H181 PolarHBondContact N-O 2.89Å; L107-I182 HydrophobicContact CB-CB 4.49Å; L107-I182 HydrophobicContact CB-CG1 4.07Å; L107-I182 HydrophobicContact CB-CG2 4.34Å; L107-I182 HydrophobicContact CD2-CG1 4.27Å; L107-I182 HydrophobicContact CD2-CG2 4.09Å; L107-I182 HydrophobicContact CG-CG2 4.33Å; L107-F183 PolarHBondContact O-N 3.17Å
108I98.9Very high98.6Very high0 Ų015.8 Ų15.80%08%0.083CC..EExtended strand (participates in β ladder)trans-117.4113.8174.7-59.4168.4000108.5V106 P122 L123 A126 A133 V134 K136 F183V106-I108 HydrophobicContact CG1-CG1 3.98Å; I108-P122 HydrophobicContact CD1-CB 4.18Å; I108-P122 HydrophobicContact CG1-CB 4.34Å; I108-P122 HydrophobicContact CG2-CB 4.01Å; I108-P122 HydrophobicContact CG2-CG 4.32Å; I108-L123 VanDerWaalsContact CD1-CA 3.46Å; I108-L123 HydrophobicContact CD1-CB 3.77Å; I108-L123 HydrophobicContact CD1-CD1 4.07Å; I108-A126 HydrophobicContact CD1-CB 4.36Å; I108-A133 HydrophobicContact CD1-CB 4.06Å; I108-V134 PolarHBondContact N-O 3.26Å; I108-K136 PolarHBondContact O-N 3.35Å; I108-F183 HydrophobicContact CG1-CB 4.36Å
109I98.9Very high98.6Very high9 Ų913.4 Ų13.45%0.0467%0.071CC..EExtended strand (participates in β ladder)trans-105.9105175.4-56170.6000108.1L107 K136 T171 L175 F183 Y184 T185 V194L107-I109 HydrophobicContact CD1-CG1 4.24Å; L107-I109 HydrophobicContact CD2-CD1 3.92Å; L107-I109 HydrophobicContact CD2-CG1 4.08Å; L107-I109 HydrophobicContact CG-CD1 4.31Å; L107-I109 HydrophobicContact CG-CG1 3.94Å; I109-K136 WeakPolarHBondContact CA-O 3.33Å; I109-K136 HydrophobicContact CG1-CB 4.33Å; I109-K136 HydrophobicContact CG2-CD 4.15Å; I109-T171 HydrophobicContact CD1-CG2 4.25Å; I109-L175 HydrophobicContact CD1-CD2 4.2Å; I109-F183 PolarHBondContact N-O 3.44Å; I109-Y184 HydrophobicContact CB-CD2 3.84Å; I109-Y184 HydrophobicContact CD1-CD2 4.15Å; I109-Y184 HydrophobicContact CG2-CD2 3.69Å; I109-Y184 HydrophobicContact CG2-CE2 4Å; I109-T185 PolarHBondContact O-N 3.17Å; I109-T185 VanDerWaalsContact O-N 3.12Å; I109-V194 HydrophobicContact CD1-CG2 4.34Å
110G98.6Very high98.6Very high5 Ų511.3 Ų11.35%0.0526%0.06CC..  trans-80.2156.3-179.600000113K136G110-K136 PolarHBondContact N-O 3.45Å
111A98.6Very high98.6Very high7 Ų710.9 Ų10.96%0.0586%0.056CC..  trans-96.9168.5172.400000111.5P115 L118 T185A111-P115 WeakPolarHBondContact O-CA 3.32Å; A111-L118 HydrophobicContact CB-CD1 3.84Å; A111-T185 HydrophobicContact CB-CG2 4.04Å
112W98.6Very high98.6Very high29 Ų298.3 Ų8.311%0.114%0.044CC..SBendtrans-91.2-18.5-173.450.7-92.9000115.1L50 P115 S138 L140 S141 Q240 I284 H288 F334L50-W112 HydrophobicContact CD2-CE3 4.35Å; L50-W112 HydrophobicContact CD2-CZ3 4.41Å; W112-P115 WeakPolarHBondContact O-CD 3.16Å; W112-S138 WeakPolarHBondContact CB-OG 3.46Å; W112-L140 HydrophobicContact CB-CB 3.82Å; W112-L140 HydrophobicContact CG-CB 3.97Å; W112-L140 HydrophobicContact CG-CD1 4.11Å; W112-S141 VanDerWaalsContact CA-OG 3.24Å; W112-S141 WeakPolarHBondContact CA-OG 3.34Å; W112-S141 WeakPolarHBondContact CB-OG 3.36Å; W112-S141 PolarHBondContact O-OG 3.32Å; W112-Q240 HydrophobicContact CH2-CB 4.09Å; W112-Q240 HydrophobicContact CH2-CG 4.13Å; W112-Q240 HydrophobicContact CZ3-CB 4Å; W112-Q240 HydrophobicContact CZ3-CG 4.2Å; W112-I284 HydrophobicContact CD2-CB 4.39Å; W112-I284 HydrophobicContact CD2-CG1 4.13Å; W112-I284 HydrophobicContact CD2-CG2 4.27Å; W112-I284 HydrophobicContact CE3-CB 3.66Å; W112-I284 HydrophobicContact CE3-CD1 4.17Å; W112-I284 HydrophobicContact CE3-CG1 3.68Å; W112-I284 HydrophobicContact CE3-CG2 3.88Å; W112-I284 HydrophobicContact CH2-CB 4.1Å; W112-I284 HydrophobicContact CH2-CG2 3.55Å; W112-I284 HydrophobicContact CZ2-CG2 4Å; W112-I284 HydrophobicContact CZ3-CB 3.52Å; W112-I284 HydrophobicContact CZ3-CG1 4.1Å; W112-I284 HydrophobicContact CZ3-CG2 3.53Å; W112-H288 AromaticContact CZ2-CE1 3.71Å; W112-F334 AromaticContact CH2-CD1 3.54Å; W112-F334 HydrophobicContact CH2-CD1 3.54Å; W112-F334 AromaticContact CH2-CE1 3.29Å; W112-F334 HydrophobicContact CH2-CE1 3.29Å; W112-F334 AromaticContact CZ2-CD1 3.73Å; W112-F334 HydrophobicContact CZ2-CD1 3.73Å; W112-F334 AromaticContact CZ2-CE1 3.4Å; W112-F334 HydrophobicContact CZ2-CE1 3.4Å; W112-F334 VanDerWaalsContact CZ2-CE1 3.4Å; W112-F334 HydrophobicContact CZ3-CE1 4.02Å
113N98.3Very high98.6Very high4 Ų47.1 Ų7.12%0.0214%0.036CC..SBendtrans-77.8-25.4-171.561.6-46.8000113.4L50 R52 L118 N237 Q240 F334L50-N113 WeakPolarHBondContact CD1-O 3.22Å; R52-N113 PolarHBondContact NH2-O 3.27Å; N113-L118 VanDerWaalsContact OD1-CD1 3.27Å; N113-L118 WeakPolarHBondContact OD1-CD1 3.33Å; N113-N237 PolarHBondContact O-ND2 3.44Å; N113-Q240 HydrophobicContact CB-CB 4.43Å; N113-Q240 WeakPolarHBondContact CB-O 3.2Å; N113-Q240 PolarHBondContact ND2-O 3.22Å; N113-F334 HydrophobicContact CB-CE1 3.95Å; N113-F334 HydrophobicContact CB-CZ 3.95Å; N113-F334 WeakPolarHBondContact ND2-CZ 3.33Å
114Y98.4Very high98.6Very high23 Ų235.1 Ų5.19%0.093%0.026CC..SBendtrans-140.272.8168.2-61.8-86.3000107.5E61 W116 A117 L118 F236 N237 T241E61-Y114 HydrophobicContact CG-CD1 3.71Å; E61-Y114 HydrophobicContact CG-CG 4.37Å; E61-Y114 VanDerWaalsContact OE2-CA 3.26Å; E61-Y114 WeakPolarHBondContact OE2-CA 3.43Å; Y114-W116 PolarHBondContact O-N 2.86Å; Y114-A117 PolarHBondContact O-N 3.12Å; Y114-L118 HydrophobicContact CD2-CD1 4.4Å; Y114-L118 WeakPolarHBondContact O-CB 3.35Å; Y114-L118 WeakPolarHBondContact O-CG 3.48Å; Y114-L118 PolarHBondContact O-N 3.03Å; Y114-F236 AromaticContact CE1-CE1 3.89Å; Y114-F236 HydrophobicContact CE1-CE1 3.89Å; Y114-F236 HydrophobicContact CE1-CZ 4.45Å; Y114-F236 AromaticContact CZ-CE1 3.93Å; Y114-F236 WeakPolarHBondContact OH-CD1 3.38Å; Y114-F236 WeakPolarHBondContact OH-CE1 3.42Å; Y114-N237 HydrophobicContact CE1-CB 4.44Å; Y114-N237 WeakPolarHBondContact OH-CB 3.49Å; Y114-T241 HydrophobicContact CE2-CG2 3.89Å; Y114-T241 PolarHBondContact OH-OG1 2.82Å
115P98.3Very high98.6Very high4 Ų45.2 Ų5.23%0.0263%0.027CC..THydrogen-bonded Turntrans-68.1-20.4-162.827.8-33.7000113.8L46 A111 W112 T119 S144L46-P115 HydrophobicContact CD2-CG 3.58Å; A111-P115 WeakPolarHBondContact O-CA 3.32Å; W112-P115 WeakPolarHBondContact O-CD 3.16Å; P115-T119 VanDerWaalsContact O-CB 3.26Å; P115-T119 WeakPolarHBondContact O-CB 3.43Å; P115-T119 PolarHBondContact O-OG1 3.22Å; P115-S144 WeakPolarHBondContact CG-OG 3.36Å
116W98.3Very high98.6Very high2 Ų25.2 Ų5.21%0.0083%0.027CC..THydrogen-bonded Turntrans-88.5-50.9175.2-67.984.5000110.7L34 I42 E61 Y114 L118 T119 L120 S144 L147 L148 L151L34-W116 HydrophobicContact CD2-CZ3 4.09Å; I42-W116 HydrophobicContact CB-CZ2 4.43Å; I42-W116 HydrophobicContact CD1-CD2 4.47Å; I42-W116 HydrophobicContact CD1-CE3 4.1Å; I42-W116 HydrophobicContact CD1-CH2 4.24Å; I42-W116 HydrophobicContact CD1-CZ3 3.97Å; I42-W116 HydrophobicContact CG1-CD2 4.27Å; I42-W116 HydrophobicContact CG1-CE3 4.25Å; I42-W116 HydrophobicContact CG1-CH2 3.76Å; I42-W116 HydrophobicContact CG1-CZ2 3.77Å; I42-W116 HydrophobicContact CG1-CZ3 4Å; I42-W116 HydrophobicContact CG2-CD2 3.86Å; I42-W116 HydrophobicContact CG2-CG 3.99Å; I42-W116 HydrophobicContact CG2-CZ2 4.28Å; E61-W116 WeakPolarHBondContact OE2-CA 3.42Å; E61-W116 WeakPolarHBondContact OE2-CB 3.38Å; E61-W116 PolarHBondContact OE2-N 2.83Å; Y114-W116 PolarHBondContact O-N 2.86Å; W116-L118 PolarHBondContact O-N 3.19Å; W116-T119 PolarHBondContact O-N 2.96Å; W116-L120 HydrophobicContact CE3-CD1 3.79Å; W116-L120 HydrophobicContact CZ3-CD1 4.38Å; W116-L120 VanDerWaalsContact O-CB 3.27Å; W116-L120 WeakPolarHBondContact O-CB 3.49Å; W116-L120 WeakPolarHBondContact O-CG 3.29Å; W116-L120 PolarHBondContact O-N 3.25Å; W116-S144 PolarHBondContact NE1-OG 3.41Å; W116-L147 HydrophobicContact CH2-CB 4.46Å; W116-L147 HydrophobicContact CH2-CD2 4.21Å; W116-L147 HydrophobicContact CH2-CG 4.1Å; W116-L147 HydrophobicContact CZ2-CB 4.14Å; W116-L147 HydrophobicContact CZ2-CD2 3.84Å; W116-L147 HydrophobicContact CZ2-CG 4.04Å; W116-L148 HydrophobicContact CE3-CD1 4.22Å; W116-L148 HydrophobicContact CH2-CB 4.04Å; W116-L148 HydrophobicContact CZ2-CB 4.45Å; W116-L148 HydrophobicContact CZ3-CB 4.36Å; W116-L148 HydrophobicContact CZ3-CD1 4.18Å; W116-L148 HydrophobicContact CZ3-CG 4.41Å; W116-L151 HydrophobicContact CH2-CD1 4.45Å
117A97.8Very high98.6Very high4 Ų45.2 Ų5.23%0.0333%0.027CC..Hα-helixtrans-61.6-48.1-178.100000111.9E61 Y114 T119 Q121E61-A117 HydrophobicContact CB-CB 4.04Å; E61-A117 HydrophobicContact CG-CB 3.93Å; E61-A117 PolarHBondContact OE2-N 2.76Å; Y114-A117 PolarHBondContact O-N 3.12Å; A117-T119 PolarHBondContact O-N 3.31Å; A117-Q121 WeakPolarHBondContact O-CB 3.37Å; A117-Q121 PolarHBondContact O-N 3.36Å
118L98.6Very high98.6Very high12 Ų125.2 Ų5.26%0.0633%0.027CC..Hα-helixtrans-75.7-7.8-175.6-59.8175.4000113.6A111 N113 Y114 W116 T185A111-L118 HydrophobicContact CB-CD1 3.84Å; N113-L118 VanDerWaalsContact OD1-CD1 3.27Å; N113-L118 WeakPolarHBondContact OD1-CD1 3.33Å; Y114-L118 HydrophobicContact CD2-CD1 4.4Å; Y114-L118 WeakPolarHBondContact O-CB 3.35Å; Y114-L118 WeakPolarHBondContact O-CG 3.48Å; Y114-L118 PolarHBondContact O-N 3.03Å; W116-L118 PolarHBondContact O-N 3.19Å; L118-T185 HydrophobicContact CD1-CG2 4.02Å; L118-T185 HydrophobicContact CD2-CG2 4.25Å; L118-T185 HydrophobicContact CG-CG2 4.48Å
119T98.6Very high98.6Very high0 Ų05.2 Ų5.20%03%0.027CC..Hα-helixtrans-101.6-47.5174.1-55.40000111P115 W116 A117 V135 L148P115-T119 VanDerWaalsContact O-CB 3.26Å; P115-T119 WeakPolarHBondContact O-CB 3.43Å; P115-T119 PolarHBondContact O-OG1 3.22Å; W116-T119 PolarHBondContact O-N 2.96Å; A117-T119 PolarHBondContact O-N 3.31Å; T119-V135 HydrophobicContact CG2-CG1 3.2Å; T119-L148 HydrophobicContact CG2-CD1 3.91Å
120L98.8Very high98.6Very high0 Ų04.8 Ų4.80%03%0.025CC..Hα-helixtrans-83.3-30.2-173-62.9-173000113.2L31 L65 W116 L123 I124 L148 L152L31-L120 HydrophobicContact CD1-CD1 4.29Å; L31-L120 HydrophobicContact CD1-CD2 4.24Å; L65-L120 HydrophobicContact CD1-CB 4.02Å; L65-L120 HydrophobicContact CD1-CD1 4.02Å; L65-L120 HydrophobicContact CD2-CB 3.75Å; W116-L120 HydrophobicContact CE3-CD1 3.79Å; W116-L120 HydrophobicContact CZ3-CD1 4.38Å; W116-L120 VanDerWaalsContact O-CB 3.27Å; W116-L120 WeakPolarHBondContact O-CB 3.49Å; W116-L120 WeakPolarHBondContact O-CG 3.29Å; W116-L120 PolarHBondContact O-N 3.25Å; L120-L123 HydrophobicContact CD2-CD2 3.9Å; L120-L123 WeakPolarHBondContact O-CB 3.37Å; L120-L123 PolarHBondContact O-N 2.92Å; L120-L123 VanDerWaalsContact O-N 3.14Å; L120-I124 VanDerWaalsContact O-CG1 3.27Å; L120-I124 WeakPolarHBondContact O-CG1 3.31Å; L120-I124 PolarHBondContact O-N 3.18Å; L120-L148 HydrophobicContact CD2-CD1 4.08Å; L120-L148 HydrophobicContact CG-CD1 4.44Å; L120-L152 HydrophobicContact CD2-CD1 4.3Å
121Q98.4Very high98.6Very high6 Ų64.6 Ų4.63%0.0282%0.023CC..Hα-helixtrans-65.3-44.6-179.4-162.8176.6-2.700112.7L65 E68 A117 L123 I124 Y393 Y411 H412L65-Q121 HydrophobicContact CD2-CB 3.79Å; L65-Q121 HydrophobicContact CD2-CG 4.47Å; E68-Q121 HydrophobicContact CG-CG 4.15Å; A117-Q121 WeakPolarHBondContact O-CB 3.37Å; A117-Q121 PolarHBondContact O-N 3.36Å; Q121-L123 VanDerWaalsContact C-N 3.3Å; Q121-L123 PolarHBondContact O-N 2.93Å; Q121-I124 PolarHBondContact O-N 3.3Å; Q121-Y393 PolarHBondContact OE1-OH 2.85Å; Q121-Y411 HydrophobicContact CB-CE2 4.1Å; Q121-Y411 HydrophobicContact CG-CD2 4.4Å; Q121-Y411 HydrophobicContact CG-CE2 3.84Å; Q121-H412 PolarHBondContact NE2-CD2 3.05Å; Q121-H412 PolarHBondContact NE2-CE1 3.32Å; Q121-H412 PolarHBondContact NE2-NE2 3.15Å; Q121-H412 VanDerWaalsContact NE2-NE2 3.16Å
122P98.8Very high98.7Very high0 Ų04.2 Ų4.20%02%0.02CC..Hα-helixtrans-62.6-35.9169.4-22.434.8000112.8I108 G125 A126 F183 Y411I108-P122 HydrophobicContact CD1-CB 4.18Å; I108-P122 HydrophobicContact CG1-CB 4.34Å; I108-P122 HydrophobicContact CG2-CB 4.01Å; I108-P122 HydrophobicContact CG2-CG 4.32Å; P122-G125 PolarHBondContact O-N 2.95Å; P122-A126 PolarHBondContact O-N 3.5Å; P122-F183 HydrophobicContact CB-CD1 3.93Å; P122-F183 HydrophobicContact CB-CD2 3.96Å; P122-F183 HydrophobicContact CB-CE1 4.03Å; P122-F183 HydrophobicContact CB-CE2 4.03Å; P122-F183 HydrophobicContact CB-CG 3.92Å; P122-F183 HydrophobicContact CB-CZ 4.08Å; P122-F183 HydrophobicContact CG-CD1 3.77Å; P122-F183 HydrophobicContact CG-CD2 4.47Å; P122-F183 HydrophobicContact CG-CE1 3.49Å; P122-F183 VanDerWaalsContact CG-CE1 3.49Å; P122-F183 HydrophobicContact CG-CE2 4.21Å; P122-F183 HydrophobicContact CG-CG 4.28Å; P122-F183 HydrophobicContact CG-CZ 3.74Å; P122-Y411 HydrophobicContact CG-CD2 4.49Å; P122-Y411 HydrophobicContact CG-CE2 4.3Å
123L98.9Very high98.7Very high0 Ų02.9 Ų2.90%02%0.015CC..Hα-helixtrans-64.4-40.6179.3178.963.3000112.1I108 L120 Q121 G125 A126 I127 A133 V135 L152 L156 Y161I108-L123 VanDerWaalsContact CD1-CA 3.46Å; I108-L123 HydrophobicContact CD1-CB 3.77Å; I108-L123 HydrophobicContact CD1-CD1 4.07Å; L120-L123 HydrophobicContact CD2-CD2 3.9Å; L120-L123 WeakPolarHBondContact O-CB 3.37Å; L120-L123 PolarHBondContact O-N 2.92Å; L120-L123 VanDerWaalsContact O-N 3.14Å; Q121-L123 VanDerWaalsContact C-N 3.3Å; Q121-L123 PolarHBondContact O-N 2.93Å; L123-G125 VanDerWaalsContact C-N 3.28Å; L123-G125 PolarHBondContact O-N 3.36Å; L123-A126 PolarHBondContact O-N 3.45Å; L123-A126 VanDerWaalsContact O-N 3.14Å; L123-I127 HydrophobicContact CD1-CD1 4.12Å; L123-I127 HydrophobicContact CD1-CG1 4.14Å; L123-I127 HydrophobicContact CD2-CD1 4.48Å; L123-I127 HydrophobicContact CG-CD1 3.87Å; L123-I127 HydrophobicContact CG-CG1 4.34Å; L123-I127 VanDerWaalsContact O-CG1 3.3Å; L123-I127 WeakPolarHBondContact O-CG1 3.48Å; L123-I127 PolarHBondContact O-N 3.42Å; L123-A133 HydrophobicContact CD1-CB 3.64Å; L123-V135 HydrophobicContact CD1-CG2 4.04Å; L123-V135 HydrophobicContact CD2-CG2 4.04Å; L123-L152 HydrophobicContact CD2-CD1 4.29Å; L123-L152 HydrophobicContact CD2-CD2 4.21Å; L123-L156 HydrophobicContact CD2-CD1 4.17Å; L123-Y161 HydrophobicContact CD1-CD1 4.05Å
124I98.9Very high98.7Very high2 Ų22.7 Ų2.71%0.011%0.014CC..Hα-helixtrans-54.4-47.7174.9-72159.3000110.1L28 L31 L65 E68 I69 A72 L120 Q121 A128L28-I124 HydrophobicContact CD2-CB 4.38Å; L28-I124 HydrophobicContact CD2-CG2 3.88Å; L31-I124 HydrophobicContact CD2-CD1 4.38Å; L31-I124 HydrophobicContact CD2-CG1 3.61Å; L65-I124 HydrophobicContact CB-CD1 4.37Å; L65-I124 HydrophobicContact CD2-CD1 3.73Å; E68-I124 HydrophobicContact CB-CD1 4.21Å; E68-I124 HydrophobicContact CG-CB 4.39Å; E68-I124 HydrophobicContact CG-CD1 4.19Å; E68-I124 HydrophobicContact CG-CG2 3.82Å; I69-I124 HydrophobicContact CD1-CD1 4.04Å; I69-I124 HydrophobicContact CD1-CG1 4.34Å; I69-I124 HydrophobicContact CG1-CD1 3.52Å; I69-I124 HydrophobicContact CG1-CG1 3.7Å; I69-I124 HydrophobicContact CG1-CG2 4.3Å; A72-I124 HydrophobicContact CB-CG2 4.22Å; L120-I124 VanDerWaalsContact O-CG1 3.27Å; L120-I124 WeakPolarHBondContact O-CG1 3.31Å; L120-I124 PolarHBondContact O-N 3.18Å; Q121-I124 PolarHBondContact O-N 3.3Å; I124-A128 WeakPolarHBondContact O-CB 3.4Å; I124-A128 PolarHBondContact O-N 3.41Å
125G98.8Very high98.7Very high3 Ų31.6 Ų1.63%0.0311%0.009CC..Hα-helixtrans-68.7-36.517700000113.7P122 L123 A128 A129P122-G125 PolarHBondContact O-N 2.95Å; L123-G125 VanDerWaalsContact C-N 3.28Å; L123-G125 PolarHBondContact O-N 3.36Å; G125-A128 PolarHBondContact O-N 2.66Å; G125-A129 WeakPolarHBondContact O-CB 3.37Å; G125-A129 PolarHBondContact O-N 2.93Å
126A98.9Very high98.7Very high0 Ų01.7 Ų1.70%01%0.009CC..Hα-helixtrans-61.9-45.3175.900000111.6V106 I108 P122 L123 A129 G130 N131 A133 L420V106-A126 HydrophobicContact CG2-CB 4.5Å; I108-A126 HydrophobicContact CD1-CB 4.36Å; P122-A126 PolarHBondContact O-N 3.5Å; L123-A126 PolarHBondContact O-N 3.45Å; L123-A126 VanDerWaalsContact O-N 3.14Å; A126-A129 PolarHBondContact O-N 2.9Å; A126-G130 PolarHBondContact O-N 3.23Å; A126-G130 VanDerWaalsContact O-N 3.12Å; A126-N131 HydrophobicContact CB-CB 4.5Å; A126-N131 WeakPolarHBondContact O-CB 3.46Å; A126-N131 PolarHBondContact O-N 2.88Å; A126-N131 PolarHBondContact O-ND2 2.98Å; A126-A133 HydrophobicContact CB-CB 4.18Å; A126-L420 HydrophobicContact CB-CD1 3.77Å
127I98.9Very high98.8Very high0 Ų01.8 Ų1.80%01%0.01CC..Hα-helixtrans-62-47.4174.5-65.8167.5000110.1R24 Q27 L28 L31 L123 A129 G130 L156 Y161R24-I127 WeakPolarHBondContact CD-O 3.42Å; Q27-I127 HydrophobicContact CB-CG2 3.71Å; L28-I127 HydrophobicContact CD2-CB 4.12Å; L28-I127 HydrophobicContact CD2-CG2 3.94Å; L28-I127 HydrophobicContact CG-CG2 3.84Å; L31-I127 HydrophobicContact CD2-CD1 4.48Å; L123-I127 HydrophobicContact CD1-CD1 4.12Å; L123-I127 HydrophobicContact CD1-CG1 4.14Å; L123-I127 HydrophobicContact CD2-CD1 4.48Å; L123-I127 HydrophobicContact CG-CD1 3.87Å; L123-I127 HydrophobicContact CG-CG1 4.34Å; L123-I127 VanDerWaalsContact O-CG1 3.3Å; L123-I127 WeakPolarHBondContact O-CG1 3.48Å; L123-I127 PolarHBondContact O-N 3.42Å; I127-A129 VanDerWaalsContact C-N 3.33Å; I127-A129 PolarHBondContact O-N 2.85Å; I127-G130 PolarHBondContact O-N 3.41Å; I127-L156 HydrophobicContact CD1-CD1 4.03Å; I127-Y161 HydrophobicContact CD1-CE1 4.43Å; I127-Y161 HydrophobicContact CG1-CD1 4.09Å; I127-Y161 HydrophobicContact CG1-CE1 3.54Å; I127-Y161 HydrophobicContact CG1-CE2 4.39Å
128A98.9Very high98.8Very high0 Ų02 Ų20%01%0.012CC..Hα-helixtrans-60-42.8179.600000111.8R24 L28 A72 L76 I124 G125 G130 F417R24-A128 WeakPolarHBondContact CD-O 3.27Å; R24-A128 PolarHBondContact NH1-O 3.04Å; L28-A128 HydrophobicContact CD1-CB 4.39Å; A72-A128 HydrophobicContact CB-CB 4.43Å; L76-A128 HydrophobicContact CD1-CB 4.21Å; L76-A128 WeakPolarHBondContact CD1-O 3.41Å; I124-A128 WeakPolarHBondContact O-CB 3.4Å; I124-A128 PolarHBondContact O-N 3.41Å; G125-A128 PolarHBondContact O-N 2.66Å; A128-G130 PolarHBondContact O-N 2.97Å; A128-F417 HydrophobicContact CB-CD2 4.19Å; A128-F417 WeakPolarHBondContact O-CE2 3.43Å
129A98.9Very high98.8Very high0 Ų05.1 Ų5.10%03%0.026CC..Hα-helixtrans-70.2-14.9176.200000113.6R24 P102 G125 A126 I127 N131 F417 L420 S421R24-A129 PolarHBondContact NH1-O 3.19Å; P102-A129 WeakPolarHBondContact CB-O 3.26Å; G125-A129 WeakPolarHBondContact O-CB 3.37Å; G125-A129 PolarHBondContact O-N 2.93Å; A126-A129 PolarHBondContact O-N 2.9Å; I127-A129 VanDerWaalsContact C-N 3.33Å; I127-A129 PolarHBondContact O-N 2.85Å; A129-N131 VanDerWaalsContact CB-ND2 3.35Å; A129-N131 WeakPolarHBondContact CB-ND2 3.2Å; A129-F417 HydrophobicContact CB-CD2 4.22Å; A129-F417 HydrophobicContact CB-CE2 4.47Å; A129-L420 HydrophobicContact CB-CB 4.13Å; A129-L420 WeakPolarHBondContact CB-O 3.15Å; A129-S421 WeakPolarHBondContact CB-OG 3.42Å
130G98.9Very high98.7Very high0 Ų08.1 Ų8.10%04%0.042CC..THydrogen-bonded Turntrans93.317.4174.600000114.4S18 A126 I127 A128S18-G130 WeakPolarHBondContact CB-O 3.34Å; S18-G130 PolarHBondContact OG-O 3.28Å; A126-G130 PolarHBondContact O-N 3.23Å; A126-G130 VanDerWaalsContact O-N 3.12Å; I127-G130 PolarHBondContact O-N 3.41Å; A128-G130 PolarHBondContact O-N 2.97Å
131N98.9Very high98.7Very high0 Ų08.1 Ų8.10%04%0.042CC..  trans-79.9158.9178.6-59.5-68.9000111.4P102 L103 G104 V106 A126 A129 Y161 L420P102-N131 WeakPolarHBondContact CB-OD1 3.31Å; L103-N131 PolarHBondContact N-OD1 3.33Å; G104-N131 PolarHBondContact N-OD1 3.09Å; G104-N131 WeakPolarHBondContact O-CA 3.48Å; G104-N131 VanDerWaalsContact O-CB 3.32Å; G104-N131 WeakPolarHBondContact O-CB 3.4Å; V106-N131 HydrophobicContact CG2-CB 3.74Å; A126-N131 HydrophobicContact CB-CB 4.5Å; A126-N131 WeakPolarHBondContact O-CB 3.46Å; A126-N131 PolarHBondContact O-N 2.88Å; A126-N131 PolarHBondContact O-ND2 2.98Å; A129-N131 VanDerWaalsContact CB-ND2 3.35Å; A129-N131 WeakPolarHBondContact CB-ND2 3.2Å; N131-Y161 WeakPolarHBondContact O-CE1 3.37Å; N131-Y161 PolarHBondContact O-OH 3.41Å; N131-L420 PolarHBondContact ND2-O 3.26Å
132A98.9Very high98.7Very high0 Ų014 Ų140%07%0.069CC..EExtended strand (participates in β ladder)trans-78.4155.9150.600000108.9A9 F13 G104 V105 V106 L160A9-A132 HydrophobicContact CB-CB 4.41Å; F13-A132 HydrophobicContact CB-CB 3.94Å; G104-A132 PolarHBondContact O-N 3.04Å; V105-A132 WeakPolarHBondContact CA-O 3.35Å; V105-A132 HydrophobicContact CG1-CB 4.45Å; V105-A132 HydrophobicContact CG2-CB 4.28Å; V106-A132 PolarHBondContact N-O 2.85Å; A132-L160 CarbonylContact C-O 3.5Å; A132-L160 WeakPolarHBondContact CA-O 3.45Å; A132-L160 HydrophobicContact CB-CD2 3.76Å; A132-L160 WeakPolarHBondContact CB-O 3.4Å
133A98.9Very high98.7Very high0 Ų017.8 Ų17.80%09%0.087CC..EExtended strand (participates in β ladder)trans-143.5128.7177.500000112.7V106 I108 L123 A126 L160 Y161 P162V106-A133 HydrophobicContact CB-CB 4.41Å; V106-A133 CarbonylContact O-C 3.52Å; V106-A133 WeakPolarHBondContact O-CA 3.4Å; I108-A133 HydrophobicContact CD1-CB 4.06Å; L123-A133 HydrophobicContact CD1-CB 3.64Å; A126-A133 HydrophobicContact CB-CB 4.18Å; A133-L160 PolarHBondContact N-O 2.85Å; A133-Y161 HydrophobicContact CB-CD1 4.19Å; A133-Y161 VanDerWaalsContact O-CA 3.3Å; A133-Y161 WeakPolarHBondContact O-CA 3.3Å; A133-P162 WeakPolarHBondContact O-CD 3.23Å
134V98.9Very high98.7Very high0 Ų017.9 Ų17.90%09%0.088CC..EExtended strand (participates in β ladder)trans-91.5121.4168.3-177.70000108.4V6 A9 V105 V106 L107 I108 P162 V164 L174 F179V6-V134 HydrophobicContact CG2-CG2 4.31Å; A9-V134 HydrophobicContact CB-CG2 4.16Å; V105-V134 HydrophobicContact CG1-CG2 4.13Å; V106-V134 PolarHBondContact O-N 2.95Å; L107-V134 HydrophobicContact CD1-CB 4.32Å; L107-V134 HydrophobicContact CD1-CG1 4.38Å; I108-V134 PolarHBondContact N-O 3.26Å; V134-P162 HydrophobicContact CG2-CG 4.09Å; V134-V164 HydrophobicContact CG1-CB 4.38Å; V134-V164 HydrophobicContact CG1-CG2 3.68Å; V134-L174 HydrophobicContact CG1-CD1 4.23Å; V134-L174 HydrophobicContact CG1-CD2 4.32Å; V134-F179 HydrophobicContact CB-CE1 4.05Å; V134-F179 HydrophobicContact CB-CZ 4.48Å; V134-F179 HydrophobicContact CG2-CE1 3.88Å; V134-F179 HydrophobicContact CG2-CZ 4.49Å
135V98.8Very high98.7Very high0 Ų018.1 Ų18.10%09%0.09CC..EExtended strand (participates in β ladder)trans-100.5119.1-174.8-177.30000109.8T119 L123 P137 L148 L152 P162 V163 V164T119-V135 HydrophobicContact CG2-CG1 3.2Å; L123-V135 HydrophobicContact CD1-CG2 4.04Å; L123-V135 HydrophobicContact CD2-CG2 4.04Å; V135-P137 WeakPolarHBondContact O-CD 3.38Å; V135-L148 HydrophobicContact CG1-CD2 3.93Å; V135-L152 HydrophobicContact CG2-CD2 4.1Å; V135-P162 PolarHBondContact N-O 3.44Å; V135-V163 HydrophobicContact CB-CG2 4.33Å; V135-V163 CarbonylContact O-C 3.55Å; V135-V163 VanDerWaalsContact O-CA 3.29Å; V135-V163 WeakPolarHBondContact O-CA 3.29Å; V135-V164 PolarHBondContact O-N 3.41Å
136K98.8Very high98.7Very high6 Ų621.2 Ų21.23%0.02611%0.111CC..EExtended strand (participates in β ladder)trans-114.492.7176.8-163.5-86.2157.5168.30109.5L107 I108 I109 G110 E139 V164 G166 T171 L174L107-K136 HydrophobicContact CD1-CB 4.47Å; I108-K136 PolarHBondContact O-N 3.35Å; I109-K136 WeakPolarHBondContact CA-O 3.33Å; I109-K136 HydrophobicContact CG1-CB 4.33Å; I109-K136 HydrophobicContact CG2-CD 4.15Å; G110-K136 PolarHBondContact N-O 3.45Å; K136-E139 IonicContact NZ-OE2 3.3Å; K136-E139 PolarHBondContact NZ-OE2 3.33Å; K136-V164 WeakPolarHBondContact CA-O 3.39Å; K136-G166 WeakPolarHBondContact CE-O 3.24Å; K136-G166 PolarHBondContact NZ-O 3.22Å; K136-T171 WeakPolarHBondContact CE-OG1 3.44Å; K136-T171 PolarHBondContact NZ-OG1 2.93Å; K136-L174 HydrophobicContact CB-CD2 4.14Å; K136-L174 HydrophobicContact CG-CD2 4.17Å
137P98.7Very high98.7Very high4 Ų422.5 Ų22.53%0.02612%0.118CC..  trans-68156.817329.8-34.7000110.8V135 A145 L148 V163 T165V135-P137 WeakPolarHBondContact O-CD 3.38Å; P137-A145 HydrophobicContact CB-CB 3.85Å; P137-A145 HydrophobicContact CG-CB 3.8Å; P137-L148 HydrophobicContact CG-CD2 4.43Å; P137-V163 HydrophobicContact CG-CG1 4.06Å; P137-T165 HydrophobicContact CG-CG2 4.15Å
138S98.6Very high98.7Very high10 Ų1022.7 Ų22.77%0.0712%0.119CC..  trans-70.6133.3177.1177.90000111.3W112 L140 S141W112-S138 WeakPolarHBondContact CB-OG 3.46Å; S138-L140 PolarHBondContact O-N 2.94Å; S138-L140 PolarHBondContact OG-N 2.85Å; S138-S141 PolarHBondContact O-N 3.42Å
139E97.7Very high98.6Very high76 Ų7627 Ų2736%0.35514%0.138SC..THydrogen-bonded Turntrans-66.5-19.7175.866.6-87.2-152.800113.6K136 S141K136-E139 IonicContact NZ-OE2 3.3Å; K136-E139 PolarHBondContact NZ-OE2 3.33Å; E139-S141 VanDerWaalsContact C-N 3.31Å
140L98.4Very high98.6Very high63 Ų6329.7 Ų29.733%0.3316%0.159SC..THydrogen-bonded Turntrans-73.6-23.4179.9-58.8-173.7000113.1W112 S138 I284W112-L140 HydrophobicContact CB-CB 3.82Å; W112-L140 HydrophobicContact CG-CB 3.97Å; W112-L140 HydrophobicContact CG-CD1 4.11Å; S138-L140 PolarHBondContact O-N 2.94Å; S138-L140 PolarHBondContact OG-N 2.85Å; L140-I284 HydrophobicContact CB-CG1 4.12Å; L140-I284 WeakPolarHBondContact O-CD1 3.24Å
141S98.5Very high98.6Very high0 Ų030 Ų300%016%0.161CC..SBendtrans-102.867.4171.4-600000108.7D49 W112 S138 E139 H143 S144 A145D49-S141 VanDerWaalsContact OD1-C 3.27Å; D49-S141 WeakPolarHBondContact OD1-CA 3.47Å; D49-S141 WeakPolarHBondContact OD2-CB 3.33Å; W112-S141 VanDerWaalsContact CA-OG 3.24Å; W112-S141 WeakPolarHBondContact CA-OG 3.34Å; W112-S141 WeakPolarHBondContact CB-OG 3.36Å; W112-S141 PolarHBondContact O-OG 3.32Å; S138-S141 PolarHBondContact O-N 3.42Å; E139-S141 VanDerWaalsContact C-N 3.31Å; S141-H143 VanDerWaalsContact C-N 3.3Å; S141-H143 PolarHBondContact O-N 2.86Å; S141-S144 PolarHBondContact O-N 3.2Å; S141-A145 WeakPolarHBondContact O-CB 3.48Å; S141-A145 PolarHBondContact O-N 2.93Å
142E98.3Very high98.6Very high130 Ų13030 Ų3061%0.60716%0.161SC*.Hα-helixtrans-57.5-41.4-168.3-175.6-179.7164.200112.6D49 A145 S146D49-E142 PolarHBondContact OD1-N 3.36Å; E142-A145 PolarHBondContact O-N 3.38Å; E142-S146 VanDerWaalsContact O-CB 3.3Å; E142-S146 WeakPolarHBondContact O-CB 3.48Å; E142-S146 PolarHBondContact O-N 3.48Å; E142-S146 PolarHBondContact O-OG 3.09Å
143H98.7Very high98.6Very high79 Ų7932.4 Ų32.437%0.36618%0.177SC..Hα-helixtrans-68.9-44.9-178.4-64.8-78000110.7A45 Q48 D49 S141 S146 L147A45-H143 HydrophobicContact CB-CB 4.01Å; Q48-H143 HydrophobicContact CB-CB 4.2Å; Q48-H143 WeakPolarHBondContact CB-CD2 3.29Å; Q48-H143 PolarHBondContact OE1-ND1 3.17Å; D49-H143 WeakPolarHBondContact OD1-CB 3.47Å; D49-H143 IonicContact OD1-CD2 3.43Å; D49-H143 PolarHBondContact OD1-CD2 3.34Å; D49-H143 IonicContact OD1-CG 2.61Å; D49-H143 PolarHBondContact OD1-N 2.93Å; S141-H143 VanDerWaalsContact C-N 3.3Å; S141-H143 PolarHBondContact O-N 2.86Å; H143-S146 PolarHBondContact O-N 3.09Å; H143-L147 VanDerWaalsContact O-CB 3.3Å; H143-L147 WeakPolarHBondContact O-CB 3.29Å; H143-L147 PolarHBondContact O-N 3.48Å
144S98.6Very high98.5Very high3 Ų338.4 Ų38.42%0.02121%0.205CC..Hα-helixtrans-63.7-42.8175.5-63.30000112.2D49 P115 W116 S141 L147 L148D49-S144 WeakPolarHBondContact OD2-CB 3.46Å; D49-S144 PolarHBondContact OD2-N 2.79Å; D49-S144 PolarHBondContact OD2-OG 3.46Å; P115-S144 WeakPolarHBondContact CG-OG 3.36Å; W116-S144 PolarHBondContact NE1-OG 3.41Å; S141-S144 PolarHBondContact O-N 3.2Å; S144-L147 PolarHBondContact O-N 3.17Å; S144-L148 VanDerWaalsContact O-CB 3.23Å; S144-L148 WeakPolarHBondContact O-CB 3.37Å; S144-L148 PolarHBondContact O-N 2.94Å
145A98.7Very high98.5Very high7 Ų739.3 Ų39.36%0.05821%0.208CC..Hα-helixtrans-63.1-44.6178.700000112.1P137 S141 E142 L148 K149P137-A145 HydrophobicContact CB-CB 3.85Å; P137-A145 HydrophobicContact CG-CB 3.8Å; S141-A145 WeakPolarHBondContact O-CB 3.48Å; S141-A145 PolarHBondContact O-N 2.93Å; E142-A145 PolarHBondContact O-N 3.38Å; A145-L148 PolarHBondContact O-N 3.49Å; A145-K149 WeakPolarHBondContact O-CB 3.45Å; A145-K149 PolarHBondContact O-N 3.03Å
146S98.7Very high98.5Very high67 Ų6739.8 Ų39.847%0.46921%0.211SC..Hα-helixtrans-64.6-44.6177.6-62.10000111.6E142 H143 K149 A150E142-S146 VanDerWaalsContact O-CB 3.3Å; E142-S146 WeakPolarHBondContact O-CB 3.48Å; E142-S146 PolarHBondContact O-N 3.48Å; E142-S146 PolarHBondContact O-OG 3.09Å; H143-S146 PolarHBondContact O-N 3.09Å; S146-K149 PolarHBondContact O-N 3.02Å; S146-A150 PolarHBondContact O-N 2.83Å
147L98.7Very high98.5Very high28 Ų2840.7 Ų40.715%0.14722%0.216CC..Hα-helixtrans-65-43177.8-174.860.8000111.4E41 I42 A45 W116 H143 S144 K149 A150 L151E41-L147 HydrophobicContact CB-CD1 4.46Å; E41-L147 HydrophobicContact CB-CD2 3.96Å; E41-L147 WeakPolarHBondContact O-CD2 3.41Å; I42-L147 HydrophobicContact CG1-CD2 4.33Å; A45-L147 HydrophobicContact CB-CD2 3.97Å; W116-L147 HydrophobicContact CH2-CB 4.46Å; W116-L147 HydrophobicContact CH2-CD2 4.21Å; W116-L147 HydrophobicContact CH2-CG 4.1Å; W116-L147 HydrophobicContact CZ2-CB 4.14Å; W116-L147 HydrophobicContact CZ2-CD2 3.84Å; W116-L147 HydrophobicContact CZ2-CG 4.04Å; H143-L147 VanDerWaalsContact O-CB 3.3Å; H143-L147 WeakPolarHBondContact O-CB 3.29Å; H143-L147 PolarHBondContact O-N 3.48Å; S144-L147 PolarHBondContact O-N 3.17Å; L147-K149 VanDerWaalsContact C-N 3.35Å; L147-K149 PolarHBondContact O-N 2.99Å; L147-A150 PolarHBondContact O-N 2.86Å; L147-L151 HydrophobicContact CD1-CD1 3.65Å; L147-L151 HydrophobicContact CD1-CD2 4.47Å; L147-L151 HydrophobicContact CD1-CG 3.83Å; L147-L151 HydrophobicContact CD2-CD1 4.3Å; L147-L151 HydrophobicContact CG-CD1 3.7Å; L147-L151 HydrophobicContact CG-CG 4.2Å; L147-L151 WeakPolarHBondContact O-CB 3.32Å; L147-L151 WeakPolarHBondContact O-CG 3.36Å; L147-L151 PolarHBondContact O-N 3.43Å
148L98.4Very high98.5Very high3 Ų347.5 Ų47.52%0.01625%0.245CC..Hα-helixtrans-62-42176.8-169.6145.7000111.4W116 T119 L120 V135 P137 S144 A145 A150 L151 L152 V163W116-L148 HydrophobicContact CE3-CD1 4.22Å; W116-L148 HydrophobicContact CH2-CB 4.04Å; W116-L148 HydrophobicContact CZ2-CB 4.45Å; W116-L148 HydrophobicContact CZ3-CB 4.36Å; W116-L148 HydrophobicContact CZ3-CD1 4.18Å; W116-L148 HydrophobicContact CZ3-CG 4.41Å; T119-L148 HydrophobicContact CG2-CD1 3.91Å; L120-L148 HydrophobicContact CD2-CD1 4.08Å; L120-L148 HydrophobicContact CG-CD1 4.44Å; V135-L148 HydrophobicContact CG1-CD2 3.93Å; P137-L148 HydrophobicContact CG-CD2 4.43Å; S144-L148 VanDerWaalsContact O-CB 3.23Å; S144-L148 WeakPolarHBondContact O-CB 3.37Å; S144-L148 PolarHBondContact O-N 2.94Å; A145-L148 PolarHBondContact O-N 3.49Å; L148-A150 VanDerWaalsContact C-N 3.32Å; L148-A150 PolarHBondContact O-N 2.97Å; L148-L151 PolarHBondContact O-N 2.94Å; L148-L152 HydrophobicContact CD2-CD2 4.47Å; L148-L152 VanDerWaalsContact O-CB 3.3Å; L148-L152 WeakPolarHBondContact O-CB 3.44Å; L148-L152 PolarHBondContact O-N 2.83Å; L148-V163 HydrophobicContact CD2-CB 4.39Å; L148-V163 HydrophobicContact CD2-CG1 3.72Å; L148-V163 HydrophobicContact CD2-CG2 3.69Å
149K98.4Very high98.5Very high92 Ų9251.3 Ų51.340%0.426%0.262SS..Hα-helixtrans-61.1-38.2174.2176.760.1173.9177.60112.6A145 S146 L147 P153 V163 T165A145-K149 WeakPolarHBondContact O-CB 3.45Å; A145-K149 PolarHBondContact O-N 3.03Å; S146-K149 PolarHBondContact O-N 3.02Å; L147-K149 VanDerWaalsContact C-N 3.35Å; L147-K149 PolarHBondContact O-N 2.99Å; K149-P153 VanDerWaalsContact O-CD 3.3Å; K149-P153 WeakPolarHBondContact O-CD 3.45Å; K149-V163 HydrophobicContact CB-CB 4.45Å; K149-V163 HydrophobicContact CB-CG1 3.99Å; K149-V163 HydrophobicContact CD-CB 3.67Å; K149-V163 HydrophobicContact CD-CG1 3.9Å; K149-V163 WeakPolarHBondContact CD-O 3.46Å; K149-V163 PolarHBondContact NZ-O 2.97Å; K149-T165 HydrophobicContact CB-CG2 3.8Å; K149-T165 HydrophobicContact CD-CG2 4.42Å; K149-T165 HydrophobicContact CG-CG2 4.06Å
150A98.6Very high98.5Very high55 Ų5547.7 Ų47.746%0.45525%0.245SC..Hα-helixtrans-74.7-40.7179.200000112.8S146 L147 L148 Q154S146-A150 PolarHBondContact O-N 2.83Å; L147-A150 PolarHBondContact O-N 2.86Å; L148-A150 VanDerWaalsContact C-N 3.32Å; L148-A150 PolarHBondContact O-N 2.97Å; A150-Q154 PolarHBondContact O-NE2 3.2Å
151L98.6Very high98.6Very high6 Ų644.8 Ų44.83%0.03123%0.229CC..Hα-helixtrans-86-43.1-172.3-67-179.9000113.5L34 R38 W116 L147 L148 P153 Q154 Y155L34-L151 HydrophobicContact CD1-CB 4.04Å; L34-L151 HydrophobicContact CG-CB 4.42Å; R38-L151 HydrophobicContact CB-CD1 3.85Å; R38-L151 HydrophobicContact CG-CD1 3.88Å; R38-L151 HydrophobicContact CG-CD2 4.19Å; W116-L151 HydrophobicContact CH2-CD1 4.45Å; L147-L151 HydrophobicContact CD1-CD1 3.65Å; L147-L151 HydrophobicContact CD1-CD2 4.47Å; L147-L151 HydrophobicContact CD1-CG 3.83Å; L147-L151 HydrophobicContact CD2-CD1 4.3Å; L147-L151 HydrophobicContact CG-CD1 3.7Å; L147-L151 HydrophobicContact CG-CG 4.2Å; L147-L151 WeakPolarHBondContact O-CB 3.32Å; L147-L151 WeakPolarHBondContact O-CG 3.36Å; L147-L151 PolarHBondContact O-N 3.43Å; L148-L151 PolarHBondContact O-N 2.94Å; L151-P153 VanDerWaalsContact C-CD 3.46Å; L151-P153 VanDerWaalsContact C-N 3.35Å; L151-Q154 WeakPolarHBondContact O-CB 3.46Å; L151-Q154 PolarHBondContact O-N 2.76Å; L151-Y155 WeakPolarHBondContact O-CD2 3.41Å
152L98.4Very high98.6Very high1 Ų145.5 Ų45.51%0.00523%0.234CC..Hα-helixtrans-54.1-43.6-170.5-156.973.5000113.4L31 L34 L120 L123 V135 L148 Q154 Y155 L156 V163L31-L152 HydrophobicContact CD1-CD1 4.09Å; L34-L152 HydrophobicContact CD1-CD1 4.07Å; L120-L152 HydrophobicContact CD2-CD1 4.3Å; L123-L152 HydrophobicContact CD2-CD1 4.29Å; L123-L152 HydrophobicContact CD2-CD2 4.21Å; V135-L152 HydrophobicContact CG2-CD2 4.1Å; L148-L152 HydrophobicContact CD2-CD2 4.47Å; L148-L152 VanDerWaalsContact O-CB 3.3Å; L148-L152 WeakPolarHBondContact O-CB 3.44Å; L148-L152 PolarHBondContact O-N 2.83Å; L152-Q154 PolarHBondContact O-N 3.48Å; L152-Y155 PolarHBondContact O-N 3.28Å; L152-L156 HydrophobicContact CD1-CD1 3.7Å; L152-L156 HydrophobicContact CD1-CG 4.19Å; L152-L156 HydrophobicContact CD2-CD1 4.42Å; L152-L156 HydrophobicContact CG-CD1 3.95Å; L152-L156 HydrophobicContact CG-CG 4.35Å; L152-L156 PolarHBondContact O-N 2.88Å; L152-V163 HydrophobicContact CB-CG2 3.75Å; L152-V163 HydrophobicContact CD2-CG2 3.39Å; L152-V163 HydrophobicContact CG-CG2 4.2Å
153P98.3Very high98.6Very high51 Ų5139.4 Ų39.433%0.33121%0.206SC..Hα-helixtrans-67.7-14178.2-20.434.5000115.3K149 L151 K158K149-P153 VanDerWaalsContact O-CD 3.3Å; K149-P153 WeakPolarHBondContact O-CD 3.45Å; L151-P153 VanDerWaalsContact C-CD 3.46Å; L151-P153 VanDerWaalsContact C-N 3.35Å; P153-K158 HydrophobicContact CB-CB 4.06Å
154Q98.6Very high98.6Very high125 Ų12536 Ų3658%0.58419%0.19SC*.Hα-helixtrans-83.1-21.8177.5-56.7-18041.200112.2A150 L151 L152A150-Q154 PolarHBondContact O-NE2 3.2Å; L151-Q154 WeakPolarHBondContact O-CB 3.46Å; L151-Q154 PolarHBondContact O-N 2.76Å; L152-Q154 PolarHBondContact O-N 3.48Å
155Y98.8Very high98.5Very high19 Ų1938.3 Ų38.38%0.07521%0.205CC..Hα-helixtrans-111.5-39.7-175.4-71.3-93.9000112.6S30 R33 L34 E37 R38 L151 L152S30-Y155 WeakPolarHBondContact CB-O 3.39Å; S30-Y155 WeakPolarHBondContact O-CD1 3.36Å; S30-Y155 PolarHBondContact OG-O 3.42Å; R33-Y155 HydrophobicContact CB-CD1 4.18Å; R33-Y155 HydrophobicContact CB-CE1 4.12Å; L34-Y155 HydrophobicContact CB-CD1 3.83Å; L34-Y155 HydrophobicContact CB-CD2 3.84Å; L34-Y155 HydrophobicContact CB-CE1 4.19Å; L34-Y155 HydrophobicContact CB-CE2 4.2Å; L34-Y155 HydrophobicContact CB-CG 3.65Å; L34-Y155 HydrophobicContact CD1-CD2 3.77Å; L34-Y155 HydrophobicContact CD1-CE2 4.47Å; L34-Y155 HydrophobicContact CD1-CG 4.1Å; L34-Y155 HydrophobicContact CG-CD2 3.85Å; L34-Y155 HydrophobicContact CG-CE2 4.14Å; L34-Y155 HydrophobicContact CG-CG 4.17Å; E37-Y155 WeakPolarHBondContact OE2-CE1 3.32Å; E37-Y155 PolarHBondContact OE2-OH 2.95Å; R38-Y155 HydrophobicContact CG-CE2 4.35Å; R38-Y155 PolarHBondContact NE-OH 3.21Å; L151-Y155 WeakPolarHBondContact O-CD2 3.41Å; L152-Y155 PolarHBondContact O-N 3.28Å
156L98.8Very high98.4Very high10 Ų1038.9 Ų38.95%0.05221%0.211CC..SBendtrans-101164.3-177.7-60.7-168.4000112.2Q27 L31 L123 I127 L152 K158 Y161Q27-L156 HydrophobicContact CB-CD2 4.35Å; Q27-L156 VanDerWaalsContact O-CD2 3.24Å; Q27-L156 WeakPolarHBondContact O-CD2 3.25Å; L31-L156 HydrophobicContact CB-CD2 4.17Å; L31-L156 HydrophobicContact CD1-CD1 4.41Å; L123-L156 HydrophobicContact CD2-CD1 4.17Å; I127-L156 HydrophobicContact CD1-CD1 4.03Å; L152-L156 HydrophobicContact CD1-CD1 3.7Å; L152-L156 HydrophobicContact CD1-CG 4.19Å; L152-L156 HydrophobicContact CD2-CD1 4.42Å; L152-L156 HydrophobicContact CG-CD1 3.95Å; L152-L156 HydrophobicContact CG-CG 4.35Å; L152-L156 PolarHBondContact O-N 2.88Å; L156-K158 PolarHBondContact O-N 2.71Å; L156-Y161 HydrophobicContact CB-CD2 3.97Å; L156-Y161 HydrophobicContact CD1-CD2 4.24Å; L156-Y161 HydrophobicContact CD1-CG 4.24Å
157D98.6Very high98.3Very high26 Ų2636.5 Ų36.514%0.13920%0.197CC..  trans-59.2107.5167.7-176-46.5000110.4R17 F23 E159 L160 Y161R17-D157 IonicContact CZ-OD1 2.83Å; R17-D157 IonicContact CZ-OD2 3.34Å; R17-D157 IonicContact NE-OD2 3.44Å; R17-D157 PolarHBondContact NE-OD2 3.44Å; R17-D157 IonicContact NH2-OD1 3.37Å; R17-D157 PolarHBondContact NH2-OD1 3.49Å; R17-D157 IonicContact NH2-OD2 2.73Å; R17-D157 PolarHBondContact NH2-OD2 3.48Å; F23-D157 HydrophobicContact CZ-CB 4.07Å; D157-E159 PolarHBondContact O-N 3.36Å; D157-E159 PolarHBondContact OD1-N 2.97Å; D157-L160 HydrophobicContact CB-CB 4.16Å; D157-L160 HydrophobicContact CB-CD1 4.23Å; D157-L160 PolarHBondContact O-N 3.14Å; D157-L160 PolarHBondContact OD1-N 2.95Å; D157-Y161 HydrophobicContact CB-CD2 3.99Å; D157-Y161 HydrophobicContact CB-CE2 4.08Å; D157-Y161 WeakPolarHBondContact O-CD2 3.41Å; D157-Y161 PolarHBondContact O-N 3.31Å
158K97.9Very high98.2Very high147 Ų14739.2 Ų39.264%0.63922%0.215SC*.THydrogen-bonded Turntrans-65.3-20-173.467.5-178.3-179.71800115P153 L156P153-K158 HydrophobicContact CB-CB 4.06Å; L156-K158 PolarHBondContact O-N 2.71Å
159E98.4Very high98.2Very high90 Ų9043.1 Ų43.142%0.42124%0.24SC..THydrogen-bonded Turntrans-90.5-37.7178.5-46.1174.4121.100110.2A9 A12 R17 D157 P162A9-E159 WeakPolarHBondContact CA-O 3.22Å; A12-E159 HydrophobicContact CB-CB 3.79Å; R17-E159 IonicContact CZ-OE2 3.72Å; R17-E159 VanDerWaalsContact CZ-OE2 3.25Å; R17-E159 IonicContact NH1-OE2 3.07Å; R17-E159 PolarHBondContact NH1-OE2 3.21Å; R17-E159 IonicContact NH2-OE2 3.4Å; R17-E159 PolarHBondContact NH2-OE2 2.86Å; D157-E159 PolarHBondContact O-N 3.36Å; D157-E159 PolarHBondContact OD1-N 2.97Å; E159-P162 WeakPolarHBondContact O-CD 3.36Å
160L98.8Very high98.1Very high0 Ų041.9 Ų41.90%024%0.236CC..THydrogen-bonded Turntrans-74.6-31.3175.6-75.2172000113.3A12 F13 R17 F23 A132 A133 D157A12-L160 HydrophobicContact CB-CD2 3.78Å; A12-L160 HydrophobicContact CB-CG 4.01Å; F13-L160 HydrophobicContact CB-CD2 4.4Å; R17-L160 HydrophobicContact CG-CD1 3.96Å; F23-L160 HydrophobicContact CE1-CD1 3.53Å; F23-L160 HydrophobicContact CZ-CD1 3.59Å; A132-L160 CarbonylContact C-O 3.5Å; A132-L160 WeakPolarHBondContact CA-O 3.45Å; A132-L160 HydrophobicContact CB-CD2 3.76Å; A132-L160 WeakPolarHBondContact CB-O 3.4Å; A133-L160 PolarHBondContact N-O 2.85Å; D157-L160 HydrophobicContact CB-CB 4.16Å; D157-L160 HydrophobicContact CB-CD1 4.23Å; D157-L160 PolarHBondContact O-N 3.14Å; D157-L160 PolarHBondContact OD1-N 2.95Å
161Y98.8Very high98.1Very high1 Ų140.2 Ų40.20%0.00422%0.22CC..SBendtrans-126.954.2-171.9-47.9-64.5000113.4Q27 L123 I127 N131 A133 L156 D157Q27-Y161 HydrophobicContact CB-CE2 4.39Å; Q27-Y161 HydrophobicContact CG-CE2 3.91Å; L123-Y161 HydrophobicContact CD1-CD1 4.05Å; I127-Y161 HydrophobicContact CD1-CE1 4.43Å; I127-Y161 HydrophobicContact CG1-CD1 4.09Å; I127-Y161 HydrophobicContact CG1-CE1 3.54Å; I127-Y161 HydrophobicContact CG1-CE2 4.39Å; N131-Y161 WeakPolarHBondContact O-CE1 3.37Å; N131-Y161 PolarHBondContact O-OH 3.41Å; A133-Y161 HydrophobicContact CB-CD1 4.19Å; A133-Y161 VanDerWaalsContact O-CA 3.3Å; A133-Y161 WeakPolarHBondContact O-CA 3.3Å; L156-Y161 HydrophobicContact CB-CD2 3.97Å; L156-Y161 HydrophobicContact CD1-CD2 4.24Å; L156-Y161 HydrophobicContact CD1-CG 4.24Å; D157-Y161 HydrophobicContact CB-CD2 3.99Å; D157-Y161 HydrophobicContact CB-CE2 4.08Å; D157-Y161 WeakPolarHBondContact O-CD2 3.41Å; D157-Y161 PolarHBondContact O-N 3.31Å
162P98.6Very high98.1Very high16 Ų1644.3 Ų44.310%0.10424%0.239CC..  trans-73.3149.6-178.932.6-37.2000111.9T5 A9 A133 V134 V135 E159T5-P162 HydrophobicContact CG2-CB 3.54Å; T5-P162 HydrophobicContact CG2-CG 3.49Å; T5-P162 VanDerWaalsContact CG2-CG 3.49Å; A9-P162 HydrophobicContact CB-CG 4.18Å; A133-P162 WeakPolarHBondContact O-CD 3.23Å; V134-P162 HydrophobicContact CG2-CG 4.09Å; V135-P162 PolarHBondContact N-O 3.44Å; E159-P162 WeakPolarHBondContact O-CD 3.36Å
163V98.6Very high98Very high1 Ų147 Ų471%0.00625%0.252CS..BIsolated β-bridgetrans-102.1131.6174.2-175.50000109.7V135 P137 L148 K149 L152 T165V135-V163 HydrophobicContact CB-CG2 4.33Å; V135-V163 CarbonylContact O-C 3.55Å; V135-V163 VanDerWaalsContact O-CA 3.29Å; V135-V163 WeakPolarHBondContact O-CA 3.29Å; P137-V163 HydrophobicContact CG-CG1 4.06Å; L148-V163 HydrophobicContact CD2-CB 4.39Å; L148-V163 HydrophobicContact CD2-CG1 3.72Å; L148-V163 HydrophobicContact CD2-CG2 3.69Å; K149-V163 HydrophobicContact CB-CB 4.45Å; K149-V163 HydrophobicContact CB-CG1 3.99Å; K149-V163 HydrophobicContact CD-CB 3.67Å; K149-V163 HydrophobicContact CD-CG1 3.9Å; K149-V163 WeakPolarHBondContact CD-O 3.46Å; K149-V163 PolarHBondContact NZ-O 2.97Å; L152-V163 HydrophobicContact CB-CG2 3.75Å; L152-V163 HydrophobicContact CD2-CG2 3.39Å; L152-V163 HydrophobicContact CG-CG2 4.2Å; V163-T165 HydrophobicContact CG1-CG2 4.36Å
164V98.3Very high98Very high7 Ų744.7 Ų44.74%0.04224%0.236CC..  trans-116115173178.90000108.2E2 T5 V134 V135 K136 L174E2-V164 HydrophobicContact CG-CG1 4.37Å; T5-V164 HydrophobicContact CG2-CG2 3.73Å; V134-V164 HydrophobicContact CG1-CB 4.38Å; V134-V164 HydrophobicContact CG1-CG2 3.68Å; V135-V164 PolarHBondContact O-N 3.41Å; K136-V164 WeakPolarHBondContact CA-O 3.39Å; V164-L174 HydrophobicContact CB-CD2 4.44Å; V164-L174 HydrophobicContact CG1-CD2 4.46Å
165T98.1Very high98Very high52 Ų5239.3 Ų39.332%0.31921%0.212SC..  trans-96.4151.6174.6520000110P137 K149 V163P137-T165 HydrophobicContact CG-CG2 4.15Å; K149-T165 HydrophobicContact CB-CG2 3.8Å; K149-T165 HydrophobicContact CD-CG2 4.42Å; K149-T165 HydrophobicContact CG-CG2 4.06Å; V163-T165 HydrophobicContact CG1-CG2 4.36Å
166G96.5Very high98Very high19 Ų1944.8 Ų44.820%0.19623%0.232CC..  trans151.5168.6178.700000111.9K136K136-G166 WeakPolarHBondContact CE-O 3.24Å; K136-G166 PolarHBondContact NZ-O 3.22Å
167G95.9Very high98Very high17 Ų1745.4 Ų45.418%0.17524%0.235CC..SBendtrans-90.1-146.8-179.900000112.8E170 T171G167-E170 PolarHBondContact N-OE2 3.46Å; G167-T171 WeakPolarHBondContact O-CB 3.47Å; G167-T171 PolarHBondContact O-N 3.22Å; G167-T171 PolarHBondContact O-OG1 3.32Å
168V96.4Very high98Very high86 Ų8651.5 Ų51.552%0.52126%0.256SS..Hα-helixtrans-59.2-46.4177.8177.70000112.9E170 T171 Q172V168-E170 PolarHBondContact O-N 2.96Å; V168-T171 PolarHBondContact O-N 2.98Å; V168-Q172 HydrophobicContact CG1-CG 4.25Å; V168-Q172 WeakPolarHBondContact O-CG 3.47Å; V168-Q172 PolarHBondContact O-N 3.33Å
169P97.8Very high98.1Very high84 Ų8444.6 Ų44.655%0.54523%0.226SC..Hα-helixtrans-60.3-45.8-177.7-24.335.6000113.3Q172 E173P169-Q172 PolarHBondContact O-N 3.19Å; P169-E173 PolarHBondContact O-N 3.44Å
170E98.2Very high98.1Very high66 Ų6641.9 Ų41.931%0.30821%0.214SC..Hα-helixtrans-67.7-39.5178.9-61.976.6-168.100110.8G167 V168 Q172 E173 L174G167-E170 PolarHBondContact N-OE2 3.46Å; V168-E170 PolarHBondContact O-N 2.96Å; E170-Q172 VanDerWaalsContact C-N 3.34Å; E170-Q172 PolarHBondContact O-N 3.37Å; E170-E173 PolarHBondContact O-N 2.86Å; E170-L174 WeakPolarHBondContact O-CB 3.09Å; E170-L174 PolarHBondContact O-N 2.89Å
171T98Very high98.1Very high20 Ų2042 Ų4212%0.12322%0.215CC..Hα-helixtrans-62.9-40.4175.6-54.30000111.4I109 K136 G167 V168 L174 L175I109-T171 HydrophobicContact CD1-CG2 4.25Å; K136-T171 WeakPolarHBondContact CE-OG1 3.44Å; K136-T171 PolarHBondContact NZ-OG1 2.93Å; G167-T171 WeakPolarHBondContact O-CB 3.47Å; G167-T171 PolarHBondContact O-N 3.22Å; G167-T171 PolarHBondContact O-OG1 3.32Å; V168-T171 PolarHBondContact O-N 2.98Å; T171-L174 PolarHBondContact O-N 3.45Å; T171-L175 HydrophobicContact CG2-CD1 4.14Å; T171-L175 HydrophobicContact CG2-CG 4.49Å; T171-L175 WeakPolarHBondContact O-CB 3.44Å; T171-L175 VanDerWaalsContact O-CG 3.3Å; T171-L175 WeakPolarHBondContact O-CG 3.48Å; T171-L175 PolarHBondContact O-N 2.71Å
172Q97.4Very high98.1Very high93 Ų9342.1 Ų42.144%0.43522%0.215SC..Hα-helixtrans-65.2-41.3176.1-74.9179.2-300112.2V168 P169 E170 L174 L175 R176V168-Q172 HydrophobicContact CG1-CG 4.25Å; V168-Q172 WeakPolarHBondContact O-CG 3.47Å; V168-Q172 PolarHBondContact O-N 3.33Å; P169-Q172 PolarHBondContact O-N 3.19Å; E170-Q172 VanDerWaalsContact C-N 3.34Å; E170-Q172 PolarHBondContact O-N 3.37Å; Q172-L174 VanDerWaalsContact C-N 3.34Å; Q172-L175 PolarHBondContact O-N 2.71Å; Q172-R176 WeakPolarHBondContact O-CG 3.43Å; Q172-R176 PolarHBondContact O-N 2.88Å
173E98.1Very high98.1Very high58 Ų5841.3 Ų41.327%0.27121%0.21SC..Hα-helixtrans-65.9-39.4175.7-177.955.5-150.800111.7E2 P169 E170 R176 Q177E2-E173 HydrophobicContact CB-CG 3.97Å; E2-E173 HydrophobicContact CG-CB 4.15Å; E2-E173 HydrophobicContact CG-CG 4.02Å; P169-E173 PolarHBondContact O-N 3.44Å; E170-E173 PolarHBondContact O-N 2.86Å; E173-R176 WeakPolarHBondContact O-CB 3.42Å; E173-R176 PolarHBondContact O-N 2.81Å; E173-R176 WeakPolarHBondContact OE2-CD 3.26Å; E173-R176 IonicContact OE2-CZ 3.75Å; E173-R176 IonicContact OE2-NE 3.79Å; E173-R176 IonicContact OE2-NH1 3.26Å; E173-R176 PolarHBondContact OE2-NH1 3.24Å; E173-Q177 PolarHBondContact O-NE2 3.49Å; E173-Q177 PolarHBondContact OE1-NE2 3.28Å
174L98.1Very high98.1Very high1 Ų142 Ų421%0.00521%0.213CC..Hα-helixtrans-62.1-46.2175.1-16560.8000111.1E2 V6 L107 V134 K136 V164 E170 T171 Q172 R176 Q177 F179E2-L174 HydrophobicContact CB-CD1 4.12Å; E2-L174 HydrophobicContact CG-CB 4.48Å; V6-L174 HydrophobicContact CG2-CD1 3.66Å; L107-L174 HydrophobicContact CD1-CD2 3.39Å; L107-L174 HydrophobicContact CD1-CG 3.94Å; L107-L174 HydrophobicContact CD2-CD2 4.36Å; L107-L174 HydrophobicContact CD2-CG 4.27Å; V134-L174 HydrophobicContact CG1-CD1 4.23Å; V134-L174 HydrophobicContact CG1-CD2 4.32Å; K136-L174 HydrophobicContact CB-CD2 4.14Å; K136-L174 HydrophobicContact CG-CD2 4.17Å; V164-L174 HydrophobicContact CB-CD2 4.44Å; V164-L174 HydrophobicContact CG1-CD2 4.46Å; E170-L174 WeakPolarHBondContact O-CB 3.09Å; E170-L174 PolarHBondContact O-N 2.89Å; T171-L174 PolarHBondContact O-N 3.45Å; Q172-L174 VanDerWaalsContact C-N 3.34Å; L174-R176 PolarHBondContact O-N 2.85Å; L174-R176 VanDerWaalsContact O-N 3.16Å; L174-Q177 WeakPolarHBondContact O-CB 3.18Å; L174-Q177 WeakPolarHBondContact O-CG 3.43Å; L174-Q177 PolarHBondContact O-N 2.9Å; L174-F179 HydrophobicContact CD1-CE2 4.41Å; L174-F179 HydrophobicContact CD1-CZ 3.85Å; L174-F179 HydrophobicContact CG-CE2 4.26Å; L174-F179 HydrophobicContact CG-CZ 4.04Å; L174-F179 WeakPolarHBondContact O-CE2 3.33Å
175L98.6Very high98.2Very high12 Ų1242 Ų426%0.06321%0.213CC..Hα-helixtrans-64.6-15.6178.1-75.3171.7000114.4L107 I109 T171 Q172 Q177 I182 V194 A197L107-L175 HydrophobicContact CD2-CD2 3.92Å; I109-L175 HydrophobicContact CD1-CD2 4.2Å; T171-L175 HydrophobicContact CG2-CD1 4.14Å; T171-L175 HydrophobicContact CG2-CG 4.49Å; T171-L175 WeakPolarHBondContact O-CB 3.44Å; T171-L175 VanDerWaalsContact O-CG 3.3Å; T171-L175 WeakPolarHBondContact O-CG 3.48Å; T171-L175 PolarHBondContact O-N 2.71Å; Q172-L175 PolarHBondContact O-N 2.71Å; L175-Q177 VanDerWaalsContact C-N 3.3Å; L175-I182 HydrophobicContact CD2-CD1 4.15Å; L175-I182 HydrophobicContact CD2-CG2 4.49Å; L175-V194 HydrophobicContact CD1-CG2 4.14Å; L175-V194 HydrophobicContact CD2-CG1 4.25Å; L175-V194 HydrophobicContact CD2-CG2 4.41Å; L175-A197 HydrophobicContact CB-CB 3.84Å; L175-A197 HydrophobicContact CD1-CB 4.5Å; L175-A197 HydrophobicContact CD2-CB 4.34Å; L175-A197 HydrophobicContact CG-CB 4.46Å
176R98.4Very high98.2Very high134 Ų13440.5 Ų40.551%0.50621%0.208SC..Hα-helixtrans-74-24.3170.7-69.6173.9-172.5118.28.4112.3Q172 E173 L174 H201Q172-R176 WeakPolarHBondContact O-CG 3.43Å; Q172-R176 PolarHBondContact O-N 2.88Å; E173-R176 WeakPolarHBondContact O-CB 3.42Å; E173-R176 PolarHBondContact O-N 2.81Å; E173-R176 WeakPolarHBondContact OE2-CD 3.26Å; E173-R176 IonicContact OE2-CZ 3.75Å; E173-R176 IonicContact OE2-NE 3.79Å; E173-R176 IonicContact OE2-NH1 3.26Å; E173-R176 PolarHBondContact OE2-NH1 3.24Å; L174-R176 PolarHBondContact O-N 2.85Å; L174-R176 VanDerWaalsContact O-N 3.16Å; R176-H201 PolarHBondContact O-NE2 3.01Å
177Q98.7Very high98.2Very high24 Ų2442.9 Ų42.911%0.11222%0.216CC..SBendtrans-74.8158.8-178.6-45.9-47.5-54.100111.1V6 E173 L174 L175 F179V6-Q177 HydrophobicContact CB-CB 4.26Å; V6-Q177 HydrophobicContact CB-CG 4.4Å; V6-Q177 HydrophobicContact CG1-CB 4.07Å; V6-Q177 HydrophobicContact CG2-CB 3.98Å; V6-Q177 HydrophobicContact CG2-CG 3.97Å; E173-Q177 PolarHBondContact O-NE2 3.49Å; E173-Q177 PolarHBondContact OE1-NE2 3.28Å; L174-Q177 WeakPolarHBondContact O-CB 3.18Å; L174-Q177 WeakPolarHBondContact O-CG 3.43Å; L174-Q177 PolarHBondContact O-N 2.9Å; L175-Q177 VanDerWaalsContact C-N 3.3Å; Q177-F179 HydrophobicContact CB-CE2 4.09Å
178R98.8Very high98.3Very high153 Ų15343.9 Ų43.958%0.57722%0.22SC*.  trans-84.4122.8178.9-176.9173.2177178.40.4110.3R10 H201R10-R178 PolarHBondContact NH2-O 2.94Å; R178-H201 HydrophobicContact CG-CB 4.27Å
179F98.9Very high98.4Very high2 Ų244.5 Ų44.51%0.00922%0.224CC..  trans-118.4156.9169.4-66.1-80.2000110.4V6 V105 L107 V134 L174 Q177 I182 T203V6-F179 HydrophobicContact CG1-CE1 4.08Å; V6-F179 HydrophobicContact CG1-CZ 4.22Å; V6-F179 HydrophobicContact CG2-CE1 3.92Å; V6-F179 HydrophobicContact CG2-CE2 4.39Å; V6-F179 HydrophobicContact CG2-CZ 3.49Å; V6-F179 VanDerWaalsContact CG2-CZ 3.49Å; V105-F179 HydrophobicContact CB-CD1 4.33Å; V105-F179 HydrophobicContact CG1-CD1 3.87Å; V105-F179 HydrophobicContact CG1-CE1 4.01Å; L107-F179 HydrophobicContact CB-CB 4.43Å; L107-F179 HydrophobicContact CB-CD1 3.68Å; L107-F179 HydrophobicContact CB-CD2 3.85Å; L107-F179 HydrophobicContact CB-CE1 3.77Å; L107-F179 HydrophobicContact CB-CE2 3.93Å; L107-F179 HydrophobicContact CB-CG 3.71Å; L107-F179 HydrophobicContact CB-CZ 3.88Å; L107-F179 HydrophobicContact CD1-CE1 4.42Å; L107-F179 HydrophobicContact CD1-CE2 4.45Å; L107-F179 HydrophobicContact CD1-CZ 4.05Å; L107-F179 HydrophobicContact CD2-CD2 4.03Å; L107-F179 HydrophobicContact CD2-CE2 3.7Å; L107-F179 HydrophobicContact CD2-CZ 4.14Å; L107-F179 HydrophobicContact CG-CE2 4.23Å; L107-F179 HydrophobicContact CG-CZ 4.23Å; V134-F179 HydrophobicContact CB-CE1 4.05Å; V134-F179 HydrophobicContact CB-CZ 4.48Å; V134-F179 HydrophobicContact CG2-CE1 3.88Å; V134-F179 HydrophobicContact CG2-CZ 4.49Å; L174-F179 HydrophobicContact CD1-CE2 4.41Å; L174-F179 HydrophobicContact CD1-CZ 3.85Å; L174-F179 HydrophobicContact CG-CE2 4.26Å; L174-F179 HydrophobicContact CG-CZ 4.04Å; L174-F179 WeakPolarHBondContact O-CE2 3.33Å; Q177-F179 HydrophobicContact CB-CE2 4.09Å; F179-I182 HydrophobicContact CB-CG1 4.04Å; F179-I182 HydrophobicContact CD2-CG1 4.34Å; F179-I182 HydrophobicContact CG-CG1 4.45Å; F179-T203 HydrophobicContact CB-CG2 4.25Å; F179-T203 WeakPolarHBondContact O-CG2 3.3Å; F179-T203 PolarHBondContact O-OG1 3.13Å
180D98.9Very high98.4Very high34 Ų3443.2 Ų43.218%0.18222%0.215CC..SBendtrans-92.8-14177.6-54.7-73.3000111.2R10 L103 G104 V105 P204R10-D180 IonicContact CZ-OD2 3.62Å; R10-D180 IonicContact NH1-OD1 2.66Å; R10-D180 IonicContact NH1-OD2 2.76Å; R10-D180 PolarHBondContact NH1-OD2 3.46Å; R10-D180 IonicContact NH2-OD2 3.96Å; R10-D180 PolarHBondContact NH2-OD2 2.99Å; L103-D180 HydrophobicContact CB-CB 4.03Å; L103-D180 WeakPolarHBondContact O-CB 3.4Å; G104-D180 WeakPolarHBondContact CA-OD2 3.49Å; V105-D180 PolarHBondContact N-OD2 3.46Å; V105-D180 PolarHBondContact O-N 3.46Å; D180-P204 WeakPolarHBondContact O-CD 3.39Å; D180-P204 VanDerWaalsContact O-CG 3.31Å; D180-P204 WeakPolarHBondContact O-CG 3.44Å
181H98.9Very high98.4Very high2 Ų240.1 Ų40.11%0.00920%0.201CC..EExtended strand (participates in β ladder)trans-156.7147.9163.8-162.887.2000110.4L103 V106 L107 P204 T206 L420L103-H181 HydrophobicContact CD1-CB 3.78Å; V106-H181 WeakPolarHBondContact CA-O 3.47Å; V106-H181 HydrophobicContact CG1-CB 4.27Å; V106-H181 HydrophobicContact CG2-CB 4.12Å; L107-H181 PolarHBondContact N-O 2.89Å; H181-P204 WeakPolarHBondContact CA-O 3.33Å; H181-T206 PolarHBondContact NE2-N 2.91Å; H181-T206 PolarHBondContact NE2-OG1 2.88Å; H181-L420 HydrophobicContact CB-CD2 4.16Å; H181-L420 WeakPolarHBondContact CD2-CD2 3.38Å
182I98.9Very high98.5Very high3 Ų344.9 Ų44.92%0.01522%0.22CC..EExtended strand (participates in β ladder)trans-119.5121.1169.2-60.7161.3000109.6L107 L175 F179 V194 A198 T203 P204 V205 T206L107-I182 HydrophobicContact CB-CB 4.49Å; L107-I182 HydrophobicContact CB-CG1 4.07Å; L107-I182 HydrophobicContact CB-CG2 4.34Å; L107-I182 HydrophobicContact CD2-CG1 4.27Å; L107-I182 HydrophobicContact CD2-CG2 4.09Å; L107-I182 HydrophobicContact CG-CG2 4.33Å; L175-I182 HydrophobicContact CD2-CD1 4.15Å; L175-I182 HydrophobicContact CD2-CG2 4.49Å; F179-I182 HydrophobicContact CB-CG1 4.04Å; F179-I182 HydrophobicContact CD2-CG1 4.34Å; F179-I182 HydrophobicContact CG-CG1 4.45Å; I182-V194 HydrophobicContact CB-CG1 4.47Å; I182-V194 HydrophobicContact CG2-CG1 3.57Å; I182-A198 HydrophobicContact CD1-CB 3.86Å; I182-T203 HydrophobicContact CD1-CG2 4Å; I182-T203 HydrophobicContact CG1-CG2 3.86Å; I182-P204 PolarHBondContact N-O 2.62Å; I182-V205 HydrophobicContact CB-CG1 4.29Å; I182-V205 CarbonylContact O-C 3.59Å; I182-V205 VanDerWaalsContact O-CA 3.24Å; I182-V205 WeakPolarHBondContact O-CA 3.48Å; I182-T206 PolarHBondContact O-N 3.14Å
183F98.9Very high98.5Very high0 Ų043.8 Ų43.80%022%0.219CC..EExtended strand (participates in β ladder)trans-104119.6173.6-162.1-67000108.8L107 I108 I109 P122 T206 E208 Y411L107-F183 PolarHBondContact O-N 3.17Å; I108-F183 HydrophobicContact CG1-CB 4.36Å; I109-F183 PolarHBondContact N-O 3.44Å; P122-F183 HydrophobicContact CB-CD1 3.93Å; P122-F183 HydrophobicContact CB-CD2 3.96Å; P122-F183 HydrophobicContact CB-CE1 4.03Å; P122-F183 HydrophobicContact CB-CE2 4.03Å; P122-F183 HydrophobicContact CB-CG 3.92Å; P122-F183 HydrophobicContact CB-CZ 4.08Å; P122-F183 HydrophobicContact CG-CD1 3.77Å; P122-F183 HydrophobicContact CG-CD2 4.47Å; P122-F183 HydrophobicContact CG-CE1 3.49Å; P122-F183 VanDerWaalsContact CG-CE1 3.49Å; P122-F183 HydrophobicContact CG-CE2 4.21Å; P122-F183 HydrophobicContact CG-CG 4.28Å; P122-F183 HydrophobicContact CG-CZ 3.74Å; F183-T206 HydrophobicContact CD2-CG2 3.88Å; F183-T206 HydrophobicContact CE2-CG2 3.51Å; F183-T206 HydrophobicContact CZ-CG2 3.85Å; F183-E208 HydrophobicContact CE1-CG 3.95Å; F183-E208 HydrophobicContact CZ-CG 3.9Å; F183-Y411 HydrophobicContact CE2-CD1 4.23Å; F183-Y411 HydrophobicContact CE2-CD2 4.37Å; F183-Y411 AromaticContact CE2-CG 3.95Å; F183-Y411 HydrophobicContact CE2-CG 3.95Å; F183-Y411 AromaticContact CZ-CD1 3.63Å; F183-Y411 HydrophobicContact CZ-CD1 3.63Å; F183-Y411 HydrophobicContact CZ-CD2 4.02Å; F183-Y411 AromaticContact CZ-CE1 3.92Å; F183-Y411 HydrophobicContact CZ-CE1 3.92Å; F183-Y411 HydrophobicContact CZ-CE2 4.36Å; F183-Y411 AromaticContact CZ-CG 3.69Å; F183-Y411 HydrophobicContact CZ-CG 3.69Å
184Y98.9Very high98.6Very high16 Ų1641 Ų416%0.06321%0.206CC..EExtended strand (participates in β ladder)trans-128.5128.7-179.5170.8-99.3000110.8I109 G186 N187 V190 V194 T206 L207 E208 L209I109-Y184 HydrophobicContact CB-CD2 3.84Å; I109-Y184 HydrophobicContact CD1-CD2 4.15Å; I109-Y184 HydrophobicContact CG2-CD2 3.69Å; I109-Y184 HydrophobicContact CG2-CE2 4Å; Y184-G186 WeakPolarHBondContact OH-CA 3.21Å; Y184-N187 PolarHBondContact OH-N 3.17Å; Y184-N187 VanDerWaalsContact OH-N 3.13Å; Y184-V190 HydrophobicContact CE1-CB 4.46Å; Y184-V190 HydrophobicContact CE1-CG1 4.38Å; Y184-V190 HydrophobicContact CE2-CG1 3.75Å; Y184-V190 VanDerWaalsContact OH-CB 3.28Å; Y184-V190 WeakPolarHBondContact OH-CB 3.28Å; Y184-V190 WeakPolarHBondContact OH-CG1 3.24Å; Y184-V194 HydrophobicContact CD1-CG2 4.47Å; Y184-V194 HydrophobicContact CD2-CG2 3.89Å; Y184-V194 HydrophobicContact CE2-CG2 4.4Å; Y184-V194 HydrophobicContact CG-CG2 3.95Å; Y184-T206 PolarHBondContact N-O 3.01Å; Y184-L207 HydrophobicContact CD1-CD2 4.18Å; Y184-L207 HydrophobicContact CG-CD2 4.49Å; Y184-L207 WeakPolarHBondContact O-CA 3.44Å; Y184-E208 PolarHBondContact O-N 2.87Å; Y184-L209 HydrophobicContact CD1-CD2 3.81Å; Y184-L209 HydrophobicContact CE1-CD2 3.63Å
185T98.9Very high98.6Very high6 Ų645.1 Ų45.14%0.03723%0.227CC..EExtended strand (participates in β ladder)trans-112.5128.8167.5-52.40000109.9I109 A111 L118 E208I109-T185 PolarHBondContact O-N 3.17Å; I109-T185 VanDerWaalsContact O-N 3.12Å; A111-T185 HydrophobicContact CB-CG2 4.04Å; L118-T185 HydrophobicContact CD1-CG2 4.02Å; L118-T185 HydrophobicContact CD2-CG2 4.25Å; L118-T185 HydrophobicContact CG-CG2 4.48Å; T185-E208 CarbonylContact C-O 3.5Å; T185-E208 VanDerWaalsContact CA-O 3.3Å; T185-E208 WeakPolarHBondContact CA-O 3.4Å; T185-E208 HydrophobicContact CG2-CB 3.99Å
186G98.3Very high98.6Very high20 Ų2051 Ų5121%0.20625%0.254CS..SBendtrans164.7-128.9175.400000113.9Y184 E208 L209 G210Y184-G186 WeakPolarHBondContact OH-CA 3.21Å; G186-E208 PolarHBondContact N-O 2.81Å; G186-L209 WeakPolarHBondContact O-CA 3.47Å; G186-G210 PolarHBondContact O-N 3.07Å
187N97.9Very high98.6Very high69 Ų6945.2 Ų45.237%0.36924%0.235SC..  trans-110156.3-174.269.775.6000112.4Y184 T189 V190 G191Y184-N187 PolarHBondContact OH-N 3.17Å; Y184-N187 VanDerWaalsContact OH-N 3.13Å; N187-T189 VanDerWaalsContact C-N 3.31Å; N187-T189 PolarHBondContact O-N 3.43Å; N187-T189 VanDerWaalsContact OD1-CB 3.31Å; N187-T189 WeakPolarHBondContact OD1-CB 3.44Å; N187-T189 PolarHBondContact OD1-N 3.35Å; N187-T189 VanDerWaalsContact OD1-N 3.16Å; N187-V190 PolarHBondContact O-N 2.95Å; N187-V190 PolarHBondContact OD1-N 3.5Å; N187-G191 PolarHBondContact O-N 3.22Å
188S97.4Very high98.6Very high38 Ų3844.2 Ų44.227%0.26623%0.23SC..Hα-helixtrans-63.8-31.4-175.360.70000114.3G191 K192S188-G191 PolarHBondContact O-N 2.91Å; S188-K192 WeakPolarHBondContact O-CG 3.1Å; S188-K192 PolarHBondContact O-N 3.04Å; S188-K192 VanDerWaalsContact O-N 3.13Å
189T97.5Very high98.6Very high99 Ų9940 Ų4061%0.60723%0.228SC*.Hα-helixtrans-61.5-48.8175.7-58.50000111N187N187-T189 VanDerWaalsContact C-N 3.31Å; N187-T189 PolarHBondContact O-N 3.43Å; N187-T189 VanDerWaalsContact OD1-CB 3.31Å; N187-T189 WeakPolarHBondContact OD1-CB 3.44Å; N187-T189 PolarHBondContact OD1-N 3.35Å; N187-T189 VanDerWaalsContact OD1-N 3.16Å
190V98.4Very high98.6Very high58 Ų5847 Ų4735%0.35226%0.259SS..Hα-helixtrans-76.1-31.8178.4176.40000111.5Y184 N187 K192 V193 V194Y184-V190 HydrophobicContact CE1-CB 4.46Å; Y184-V190 HydrophobicContact CE1-CG1 4.38Å; Y184-V190 HydrophobicContact CE2-CG1 3.75Å; Y184-V190 VanDerWaalsContact OH-CB 3.28Å; Y184-V190 WeakPolarHBondContact OH-CB 3.28Å; Y184-V190 WeakPolarHBondContact OH-CG1 3.24Å; N187-V190 PolarHBondContact O-N 2.95Å; N187-V190 PolarHBondContact OD1-N 3.5Å; V190-K192 PolarHBondContact O-N 3.2Å; V190-V193 WeakPolarHBondContact O-CB 3.17Å; V190-V193 PolarHBondContact O-N 3.47Å; V190-V194 HydrophobicContact CG1-CG2 4.33Å; V190-V194 WeakPolarHBondContact O-CG2 3.5Å; V190-V194 PolarHBondContact O-N 3.22Å
191G98.8Very high98.6Very high1 Ų148.7 Ų48.71%0.0127%0.265CS..Hα-helixtrans-55.4-38.8172.900000112.8N187 S188 V194 M195N187-G191 PolarHBondContact O-N 3.22Å; S188-G191 PolarHBondContact O-N 2.91Å; G191-V194 PolarHBondContact O-N 3.19Å; G191-M195 WeakPolarHBondContact O-CB 3.24Å; G191-M195 PolarHBondContact O-N 3.27Å
192K98.8Very high98.6Very high119 Ų11956.1 Ų56.152%0.51730%0.304SS..Hα-helixtrans-63.8-42.7173.2-69.2167.3-172172.10112.3S188 V190 V194 M195 E196S188-K192 WeakPolarHBondContact O-CG 3.1Å; S188-K192 PolarHBondContact O-N 3.04Å; S188-K192 VanDerWaalsContact O-N 3.13Å; V190-K192 PolarHBondContact O-N 3.2Å; K192-V194 VanDerWaalsContact C-N 3.35Å; K192-M195 PolarHBondContact O-N 3.42Å; K192-E196 WeakPolarHBondContact O-CB 3.46Å; K192-E196 PolarHBondContact O-N 2.8Å
193V98.8Very high98.6Very high70 Ų7056.6 Ų56.642%0.42431%0.307SS..Hα-helixtrans-63.2-42.1177177.80000111.1V190 E196 A197V190-V193 WeakPolarHBondContact O-CB 3.17Å; V190-V193 PolarHBondContact O-N 3.47Å; V193-E196 PolarHBondContact O-N 3.15Å; V193-A197 PolarHBondContact O-N 2.77Å
194V98.9Very high98.6Very high1 Ų159.7 Ų59.71%0.00633%0.327CS..Hα-helixtrans-61.4-47.4175.5171.70000110.6I109 L175 I182 Y184 V190 G191 K192 E196 A197 A198 L207I109-V194 HydrophobicContact CD1-CG2 4.34Å; L175-V194 HydrophobicContact CD1-CG2 4.14Å; L175-V194 HydrophobicContact CD2-CG1 4.25Å; L175-V194 HydrophobicContact CD2-CG2 4.41Å; I182-V194 HydrophobicContact CB-CG1 4.47Å; I182-V194 HydrophobicContact CG2-CG1 3.57Å; Y184-V194 HydrophobicContact CD1-CG2 4.47Å; Y184-V194 HydrophobicContact CD2-CG2 3.89Å; Y184-V194 HydrophobicContact CE2-CG2 4.4Å; Y184-V194 HydrophobicContact CG-CG2 3.95Å; V190-V194 HydrophobicContact CG1-CG2 4.33Å; V190-V194 WeakPolarHBondContact O-CG2 3.5Å; V190-V194 PolarHBondContact O-N 3.22Å; G191-V194 PolarHBondContact O-N 3.19Å; K192-V194 VanDerWaalsContact C-N 3.35Å; V194-E196 PolarHBondContact O-N 3.02Å; V194-A197 PolarHBondContact O-N 2.63Å; V194-A198 WeakPolarHBondContact O-CB 3.45Å; V194-A198 PolarHBondContact O-N 3.37Å; V194-L207 HydrophobicContact CB-CD2 4.47Å; V194-L207 HydrophobicContact CG1-CD2 4.12Å
195M98.9Very high98.6Very high87 Ų8759.8 Ų59.843%0.42933%0.329SS..Hα-helixtrans-64.9-38179.4-166.7177.2-176.900112.5G191 K192 A198 A199 V205 L207 M408G191-M195 WeakPolarHBondContact O-CB 3.24Å; G191-M195 PolarHBondContact O-N 3.27Å; K192-M195 PolarHBondContact O-N 3.42Å; M195-A198 WeakPolarHBondContact O-CB 3.24Å; M195-A198 PolarHBondContact O-N 3.29Å; M195-A199 PolarHBondContact O-N 3Å; M195-V205 HydrophobicContact CG-CG2 4.3Å; M195-L207 HydrophobicContact CB-CD1 4.32Å; M195-L207 HydrophobicContact SD-CD1 4.46Å; M195-M408 HydrophobicContact CE-CE 3.78Å; M195-M408 HydrophobicContact CE-SD 4.03Å; M195-M408 HydrophobicContact SD-CE 3.73Å; M195-M408 HydrophobicContact SD-SD 4.33Å
196E98.9Very high98.6Very high135 Ų13559.5 Ų59.563%0.63133%0.328SS*.Hα-helixtrans-63-42.3174.6-174.3-175.3168.100111.8K192 V193 V194 A199K192-E196 WeakPolarHBondContact O-CB 3.46Å; K192-E196 PolarHBondContact O-N 2.8Å; V193-E196 PolarHBondContact O-N 3.15Å; V194-E196 PolarHBondContact O-N 3.02Å; E196-A199 PolarHBondContact O-N 3.06Å
197A98.8Very high98.6Very high13 Ų1358.8 Ų58.811%0.10732%0.319CS..Hα-helixtrans-65.2-42.8174.500000111.8L175 V193 V194 A199 K200L175-A197 HydrophobicContact CB-CB 3.84Å; L175-A197 HydrophobicContact CD1-CB 4.5Å; L175-A197 HydrophobicContact CD2-CB 4.34Å; L175-A197 HydrophobicContact CG-CB 4.46Å; V193-A197 PolarHBondContact O-N 2.77Å; V194-A197 PolarHBondContact O-N 2.63Å; A197-A199 VanDerWaalsContact C-N 3.28Å; A197-A199 PolarHBondContact O-N 3.17Å; A197-K200 WeakPolarHBondContact O-CB 3.32Å; A197-K200 PolarHBondContact O-N 3.03Å
198A98.9Very high98.7Very high2 Ų255.7 Ų55.72%0.01730%0.303CS..Hα-helixtrans-60.1-36.5177.700000112.6I182 V194 M195 K200 H201 L202 T203 V205I182-A198 HydrophobicContact CD1-CB 3.86Å; V194-A198 WeakPolarHBondContact O-CB 3.45Å; V194-A198 PolarHBondContact O-N 3.37Å; M195-A198 WeakPolarHBondContact O-CB 3.24Å; M195-A198 PolarHBondContact O-N 3.29Å; A198-K200 PolarHBondContact O-N 3.27Å; A198-H201 PolarHBondContact O-N 2.88Å; A198-H201 VanDerWaalsContact O-N 3.11Å; A198-L202 PolarHBondContact O-N 2.74Å; A198-L202 VanDerWaalsContact O-N 3.15Å; A198-T203 PolarHBondContact O-N 2.84Å; A198-V205 HydrophobicContact CB-CG1 3.44Å; A198-V205 VanDerWaalsContact CB-CG1 3.44Å
199A98.8Very high98.7Very high64 Ų6454.3 Ų54.353%0.52929%0.292SS..Hα-helixtrans-58.8-29.4179.200000113.3M195 E196 A197 H201 L202M195-A199 PolarHBondContact O-N 3Å; E196-A199 PolarHBondContact O-N 3.06Å; A197-A199 VanDerWaalsContact C-N 3.28Å; A197-A199 PolarHBondContact O-N 3.17Å; A199-H201 PolarHBondContact O-N 2.97Å; A199-L202 PolarHBondContact O-N 2.86Å
200K98.7Very high98.7Very high151 Ų15150 Ų5066%0.65727%0.267SS*.THydrogen-bonded Turntrans-63.2-26.3178.7-61.9-179.4-179.7176.70113.4A197 A198A197-K200 WeakPolarHBondContact O-CB 3.32Å; A197-K200 PolarHBondContact O-N 3.03Å; A198-K200 PolarHBondContact O-N 3.27Å
201H98.8Very high98.6Very high69 Ų6948.2 Ų48.232%0.31926%0.26SS..THydrogen-bonded Turntrans-116.15.6-178.6-63.3-63.9000112.9R176 R178 A198 A199 T203R176-H201 PolarHBondContact O-NE2 3.01Å; R178-H201 HydrophobicContact CG-CB 4.27Å; A198-H201 PolarHBondContact O-N 2.88Å; A198-H201 VanDerWaalsContact O-N 3.11Å; A199-H201 PolarHBondContact O-N 2.97Å; H201-T203 WeakPolarHBondContact CB-OG1 3.44Å; H201-T203 PolarHBondContact O-N 3.39Å
202L98.8Very high98.6Very high158 Ų15849.4 Ų49.483%0.82727%0.265SS*.THydrogen-bonded Turntrans52.735.4-169.8-57.2176.1000112.5A198 A199A198-L202 PolarHBondContact O-N 2.74Å; A198-L202 VanDerWaalsContact O-N 3.15Å; A199-L202 PolarHBondContact O-N 2.86Å
203T98.9Very high98.6Very high13 Ų1343.7 Ų43.78%0.0824%0.24CC..  trans-77.4126-178.3-59.40000109.8F179 I182 A198 H201F179-T203 HydrophobicContact CB-CG2 4.25Å; F179-T203 WeakPolarHBondContact O-CG2 3.3Å; F179-T203 PolarHBondContact O-OG1 3.13Å; I182-T203 HydrophobicContact CD1-CG2 4Å; I182-T203 HydrophobicContact CG1-CG2 3.86Å; A198-T203 PolarHBondContact O-N 2.84Å; H201-T203 WeakPolarHBondContact CB-OG1 3.44Å; H201-T203 PolarHBondContact O-N 3.39Å
204P98.9Very high98.6Very high64 Ų6440.4 Ų40.442%0.41622%0.221SC..  trans-64.4149.8171.727.3-33.7000111D180 H181 I182D180-P204 WeakPolarHBondContact O-CD 3.39Å; D180-P204 VanDerWaalsContact O-CG 3.31Å; D180-P204 WeakPolarHBondContact O-CG 3.44Å; H181-P204 WeakPolarHBondContact CA-O 3.33Å; I182-P204 PolarHBondContact N-O 2.62Å
205V98.9Very high98.6Very high18 Ų1840.4 Ų40.411%0.10922%0.22CC..EExtended strand (participates in β ladder)trans-124.9147.1-178.9-59.20000112I182 M195 A198 L207 M408I182-V205 HydrophobicContact CB-CG1 4.29Å; I182-V205 CarbonylContact O-C 3.59Å; I182-V205 VanDerWaalsContact O-CA 3.24Å; I182-V205 WeakPolarHBondContact O-CA 3.48Å; M195-V205 HydrophobicContact CG-CG2 4.3Å; A198-V205 HydrophobicContact CB-CG1 3.44Å; A198-V205 VanDerWaalsContact CB-CG1 3.44Å; V205-L207 HydrophobicContact CB-CD2 4.12Å; V205-L207 HydrophobicContact CB-CG 4.22Å; V205-L207 HydrophobicContact CG2-CD1 4.13Å; V205-L207 HydrophobicContact CG2-CD2 4.27Å; V205-L207 HydrophobicContact CG2-CG 3.89Å; V205-M408 HydrophobicContact CG2-CG 4.38Å; V205-M408 HydrophobicContact CG2-SD 3.88Å
206T98.9Very high98.6Very high0 Ų036.3 Ų36.30%020%0.2CC..EExtended strand (participates in β ladder)trans-113.5121.8157.9-57.90000107.2H181 I182 F183 Y184 E208 M408 Q419H181-T206 PolarHBondContact NE2-N 2.91Å; H181-T206 PolarHBondContact NE2-OG1 2.88Å; I182-T206 PolarHBondContact O-N 3.14Å; F183-T206 HydrophobicContact CD2-CG2 3.88Å; F183-T206 HydrophobicContact CE2-CG2 3.51Å; F183-T206 HydrophobicContact CZ-CG2 3.85Å; Y184-T206 PolarHBondContact N-O 3.01Å; T206-E208 HydrophobicContact CG2-CG 4.39Å; T206-M408 WeakPolarHBondContact CA-O 3.36Å; T206-Q419 WeakPolarHBondContact OG1-CG 3.3Å; T206-Q419 PolarHBondContact OG1-NE2 3.26Å
207L98.9Very high98.6Very high6 Ų629.9 Ų29.93%0.03117%0.17CC..EExtended strand (participates in β ladder)trans-118.3107.4-178.5-56.5-179.1000108.5Y184 V194 M195 V205 L209 G407 M408Y184-L207 HydrophobicContact CD1-CD2 4.18Å; Y184-L207 HydrophobicContact CG-CD2 4.49Å; Y184-L207 WeakPolarHBondContact O-CA 3.44Å; V194-L207 HydrophobicContact CB-CD2 4.47Å; V194-L207 HydrophobicContact CG1-CD2 4.12Å; M195-L207 HydrophobicContact CB-CD1 4.32Å; M195-L207 HydrophobicContact SD-CD1 4.46Å; V205-L207 HydrophobicContact CB-CD2 4.12Å; V205-L207 HydrophobicContact CB-CG 4.22Å; V205-L207 HydrophobicContact CG2-CD1 4.13Å; V205-L207 HydrophobicContact CG2-CD2 4.27Å; V205-L207 HydrophobicContact CG2-CG 3.89Å; L207-L209 HydrophobicContact CB-CD1 4.21Å; L207-L209 HydrophobicContact CB-CD2 4.2Å; L207-L209 HydrophobicContact CB-CG 4.06Å; L207-G407 CarbonylContact O-C 3.45Å; L207-G407 WeakPolarHBondContact O-CA 2.95Å; L207-M408 HydrophobicContact CB-CG 4.24Å; L207-M408 HydrophobicContact CD1-CE 4.41Å; L207-M408 HydrophobicContact CD1-CG 4.2Å; L207-M408 HydrophobicContact CD1-SD 4.48Å; L207-M408 HydrophobicContact CG-CG 4.18Å; L207-M408 PolarHBondContact N-O 2.91Å; L207-M408 PolarHBondContact O-N 3.14Å
208E98.8Very high98.6Very high4 Ų429.7 Ų29.72%0.01917%0.167CC..EExtended strand (participates in β ladder)trans-97.399.6173.3-64-61.2155.900108.3F183 Y184 T185 G186 T206 G401 Y411F183-E208 HydrophobicContact CE1-CG 3.95Å; F183-E208 HydrophobicContact CZ-CG 3.9Å; Y184-E208 PolarHBondContact O-N 2.87Å; T185-E208 CarbonylContact C-O 3.5Å; T185-E208 VanDerWaalsContact CA-O 3.3Å; T185-E208 WeakPolarHBondContact CA-O 3.4Å; T185-E208 HydrophobicContact CG2-CB 3.99Å; G186-E208 PolarHBondContact N-O 2.81Å; T206-E208 HydrophobicContact CG2-CG 4.39Å; E208-G401 WeakPolarHBondContact OE1-CA 3.2Å; E208-G401 WeakPolarHBondContact OE2-CA 3.38Å; E208-Y411 HydrophobicContact CG-CD1 4.12Å; E208-Y411 HydrophobicContact CG-CE1 3.79Å; E208-Y411 WeakPolarHBondContact OE1-CD1 3.48Å
209L98.7Very high98.4Very high9 Ų934.2 Ų34.25%0.04719%0.187CC..  trans-112.6175.7-171.3-47.2173.1000111.2Y184 G186 L207 Q405 S406Y184-L209 HydrophobicContact CD1-CD2 3.81Å; Y184-L209 HydrophobicContact CE1-CD2 3.63Å; G186-L209 WeakPolarHBondContact O-CA 3.47Å; L207-L209 HydrophobicContact CB-CD1 4.21Å; L207-L209 HydrophobicContact CB-CD2 4.2Å; L207-L209 HydrophobicContact CB-CG 4.06Å; L209-Q405 WeakPolarHBondContact CB-O 3.43Å; L209-Q405 VanDerWaalsContact CD1-O 3.31Å; L209-Q405 WeakPolarHBondContact CD1-O 3.49Å; L209-S406 CarbonylContact C-O 3.51Å; L209-S406 WeakPolarHBondContact CA-O 3.23Å; L209-S406 WeakPolarHBondContact CB-O 3.41Å; L209-S406 PolarHBondContact N-O 3.45Å
210G96.3Very high97.9Very high8 Ų835.9 Ų35.98%0.08219%0.187CC..  trans-91.9-163.9-179.800000114.4G186 E332 S406G186-G210 PolarHBondContact O-N 3.07Å; G210-E332 WeakPolarHBondContact CA-OE1 3.46Å; G210-S406 VanDerWaalsContact O-CA 3.31Å; G210-S406 WeakPolarHBondContact O-CA 3.3Å; G210-S406 WeakPolarHBondContact O-CB 3.36Å
211G97.1Very high97.6Very high20 Ų2029.8 Ų29.821%0.20616%0.162CC..  trans154.4169.1175.900000111S213 E332G211-S213 PolarHBondContact O-N 2.88Å; G211-S213 VanDerWaalsContact O-N 3.13Å; G211-E332 VanDerWaalsContact N-CD 3.34Å; G211-E332 PolarHBondContact N-OE1 2.77Å; G211-E332 VanDerWaalsContact N-OE1 3.11Å
212K98.8Very high97.6Very high26 Ų2631 Ų3111%0.11317%0.171CC..  trans-8492.7179.4-60.5-177.172.668.30109.9P214 D246 Y247 L328 M329 E331 P359K212-P214 WeakPolarHBondContact O-CD 3.4Å; K212-D246 HydrophobicContact CB-CB 4.18Å; K212-D246 WeakPolarHBondContact CB-OD1 3.4Å; K212-D246 WeakPolarHBondContact CE-OD1 3.4Å; K212-D246 WeakPolarHBondContact CG-OD1 3.44Å; K212-D246 IonicContact NZ-OD1 3.2Å; K212-D246 PolarHBondContact NZ-OD1 2.97Å; K212-D246 IonicContact NZ-OD2 3.97Å; K212-Y247 HydrophobicContact CB-CD1 4.03Å; K212-Y247 HydrophobicContact CB-CE1 3.74Å; K212-L328 PolarHBondContact NZ-O 3Å; K212-M329 WeakPolarHBondContact CD-O 3.1Å; K212-M329 WeakPolarHBondContact CE-O 3.27Å; K212-E331 WeakPolarHBondContact CD-O 3.23Å; K212-E331 PolarHBondContact NZ-O 2.89Å; K212-P359 WeakPolarHBondContact O-CB 3.4Å
213S98.9Very high97.5Very high0 Ų024.9 Ų24.90%014%0.139CC..  trans-68.2107.4178.9-63.20000111.5G211 C242 A244 D246 A361G211-S213 PolarHBondContact O-N 2.88Å; G211-S213 VanDerWaalsContact O-N 3.13Å; S213-C242 PolarHBondContact OG-O 2.77Å; S213-A244 WeakPolarHBondContact CB-O 3.21Å; S213-D246 PolarHBondContact O-N 3.41Å; S213-A361 VanDerWaalsContact CA-O 3.28Å; S213-A361 WeakPolarHBondContact CA-O 3.11Å; S213-A361 VanDerWaalsContact CB-O 3.24Å; S213-A361 WeakPolarHBondContact CB-O 3.2Å; S213-A361 PolarHBondContact OG-N 3.05Å; S213-A361 PolarHBondContact OG-O 3.16Å
214P98.9Very high97.4Very high1 Ų130.7 Ų30.71%0.00617%0.168CC..EExtended strand (participates in β ladder)trans-69.4147.8-179.127.6-35.3000112.4K212 Y247 I353 P359 A361 L362 Y363K212-P214 WeakPolarHBondContact O-CD 3.4Å; P214-Y247 HydrophobicContact CB-CE1 4.06Å; P214-Y247 HydrophobicContact CB-CE2 4.02Å; P214-I353 HydrophobicContact CB-CD1 4.02Å; P214-I353 HydrophobicContact CB-CG1 3.91Å; P214-I353 HydrophobicContact CG-CD1 4.03Å; P214-I353 HydrophobicContact CG-CG1 3.98Å; P214-I353 HydrophobicContact CG-CG2 4.3Å; P214-P359 HydrophobicContact CG-CG 4.24Å; P214-A361 WeakPolarHBondContact CD-O 3.09Å; P214-L362 HydrophobicContact CB-CD1 4.36Å; P214-L362 HydrophobicContact CG-CB 4.47Å; P214-L362 HydrophobicContact CG-CD1 3.61Å; P214-Y363 PolarHBondContact O-N 3.02Å
215C98.9Very high97.4Very high0 Ų030.2 Ų30.20%017%0.165CC..EExtended strand (participates in β ladder)trans-125103.6169.6-171.90000110.8I230 P245 Y247 I248 L249 Y363 F365C215-I230 WeakPolarHBondContact SG-CD1 3.25Å; C215-P245 HydrophobicContact CB-CB 4Å; C215-Y247 WeakPolarHBondContact CB-O 3.15Å; C215-Y247 PolarHBondContact N-O 3.45Å; C215-I248 HydrophobicContact CB-CG1 4.37Å; C215-I248 CarbonylContact O-C 3.54Å; C215-I248 VanDerWaalsContact O-CA 3.27Å; C215-I248 WeakPolarHBondContact O-CA 3.43Å; C215-L249 PolarHBondContact O-N 3Å; C215-Y363 WeakPolarHBondContact CA-O 3.42Å; C215-F365 VanDerWaalsContact SG-CE2 3.57Å
216Y98.9Very high97.4Very high2 Ų229.5 Ų29.51%0.00816%0.16CC..EExtended strand (participates in β ladder)trans-86.9129.3175.5179.1-106.3000110.7D218 L249 V343 V346 A349 Y363 V364 F365 V371 M375Y216-D218 HydrophobicContact CE1-CB 3.89Å; Y216-L249 WeakPolarHBondContact CA-O 3.18Å; Y216-L249 HydrophobicContact CD2-CB 4.01Å; Y216-L249 WeakPolarHBondContact CD2-O 3.48Å; Y216-V343 HydrophobicContact CE2-CG2 4.23Å; Y216-V346 HydrophobicContact CE1-CB 4.37Å; Y216-V346 HydrophobicContact CE1-CG2 4.23Å; Y216-V346 PolarHBondContact OH-N 2.99Å; Y216-A349 HydrophobicContact CD2-CB 3.47Å; Y216-A349 VanDerWaalsContact CD2-CB 3.47Å; Y216-A349 HydrophobicContact CE2-CB 3.63Å; Y216-A349 HydrophobicContact CG-CB 4.31Å; Y216-Y363 PolarHBondContact N-O 2.85Å; Y216-V364 HydrophobicContact CD1-CG1 4.28Å; Y216-F365 PolarHBondContact O-N 2.68Å; Y216-V371 HydrophobicContact CD1-CG1 4.41Å; Y216-V371 HydrophobicContact CE1-CG1 3.8Å; Y216-M375 HydrophobicContact CD1-CE 3.61Å; Y216-M375 HydrophobicContact CD2-CE 4.16Å; Y216-M375 HydrophobicContact CE1-CE 4.22Å; Y216-M375 HydrophobicContact CG-CE 3.56Å
217I98.7Very high97.4Very high0 Ų029.5 Ų29.50%016%0.16CC..EExtended strand (participates in β ladder)trans-114.6114.6173.1-51.5176.6000108.1L223 I230 I248 L249 C250 I254 V258 F365I217-L223 HydrophobicContact CG2-CD2 3.58Å; I217-I230 HydrophobicContact CD1-CD1 3.5Å; I217-I230 VanDerWaalsContact CD1-CD1 3.5Å; I217-I230 HydrophobicContact CG1-CD1 3.88Å; I217-I248 HydrophobicContact CD1-CD1 4.1Å; I217-I248 HydrophobicContact CD1-CG1 4.4Å; I217-I248 HydrophobicContact CD1-CG2 3.72Å; I217-I248 HydrophobicContact CG1-CG2 4.06Å; I217-L249 PolarHBondContact N-O 3.49Å; I217-C250 HydrophobicContact CB-CB 4.27Å; I217-I254 HydrophobicContact CB-CD1 4.43Å; I217-I254 HydrophobicContact CG2-CD1 4.02Å; I217-V258 HydrophobicContact CD1-CG1 3.98Å; I217-V258 HydrophobicContact CD1-CG2 3.99Å; I217-F365 HydrophobicContact CG1-CB 4.49Å; I217-F365 HydrophobicContact CG2-CB 4.42Å
218D97.9Very high97.4Very high8 Ų833.8 Ų33.84%0.04318%0.176CC..  trans-75.6152.1172.2-170.18.6000110.6Y216 D220 C221 F365 S366Y216-D218 HydrophobicContact CE1-CB 3.89Å; D218-D220 PolarHBondContact O-N 2.73Å; D218-C221 PolarHBondContact O-SG 2.91Å; D218-F365 VanDerWaalsContact CB-O 3.24Å; D218-F365 WeakPolarHBondContact CB-O 3.45Å; D218-F365 PolarHBondContact N-O 2.66Å; D218-S366 WeakPolarHBondContact OD2-CB 3.18Å; D218-S366 PolarHBondContact OD2-OG 3.12Å
219K93.9Very high97.4Very high98 Ų9838 Ų3843%0.42619%0.192SC..SBendtrans-67.7-26.4176.258161.3168.7-90.90112.8C221 E251 I254K219-C221 VanDerWaalsContact C-N 3.3Å; K219-C221 PolarHBondContact O-N 2.88Å; K219-E251 VanDerWaalsContact NZ-CD 3.29Å; K219-E251 IonicContact NZ-OE1 3.98Å; K219-E251 PolarHBondContact NZ-OE1 3.25Å; K219-E251 IonicContact NZ-OE2 2.68Å; K219-E251 PolarHBondContact NZ-OE2 3.31Å; K219-I254 HydrophobicContact CB-CG2 4.13Å
220D88.7Confident97.4Very high99 Ų9937.6 Ų37.653%0.52919%0.19SC..SBendtrans-93.152-178.8-65.9-19.8000111.5D218 S367D218-D220 PolarHBondContact O-N 2.73Å; D220-S367 VanDerWaalsContact O-CB 3.24Å; D220-S367 WeakPolarHBondContact O-CB 3.2Å; D220-S367 PolarHBondContact O-N 2.67Å; D220-S367 VanDerWaalsContact O-N 3.13Å; D220-S367 PolarHBondContact O-OG 2.67Å
221C93.8Very high97.5Very high22 Ų2237.2 Ų37.215%0.14919%0.186CC..SBendtrans-136.7162.7172.581.70000113D218 K219 L223D218-C221 PolarHBondContact O-SG 2.91Å; K219-C221 VanDerWaalsContact C-N 3.3Å; K219-C221 PolarHBondContact O-N 2.88Å; C221-L223 PolarHBondContact O-N 3.29Å
222D97.3Very high97.6Very high95 Ų9540.5 Ų40.551%0.50819%0.192SC..  trans-70.396.8169.3-173.9-27.5000109.7I224 V225 A226D222-I224 VanDerWaalsContact C-N 3.25Å; D222-I224 PolarHBondContact O-N 2.95Å; D222-I224 WeakPolarHBondContact OD1-CB 3.4Å; D222-I224 PolarHBondContact OD1-N 3.16Å; D222-V225 HydrophobicContact CB-CB 4.26Å; D222-V225 HydrophobicContact CB-CG2 4.36Å; D222-V225 PolarHBondContact O-N 3.38Å; D222-V225 PolarHBondContact OD1-N 3.18Å; D222-V225 VanDerWaalsContact OD1-N 3.1Å; D222-V225 WeakPolarHBondContact OD2-CG2 3.09Å; D222-A226 WeakPolarHBondContact O-CB 3.27Å; D222-A226 PolarHBondContact O-N 2.9Å
223L97.4Very high97.6Very high29 Ų2939.2 Ų39.215%0.15219%0.187CC..Hα-helixtrans-63.8-29.2-178-67.7177.7000112.8I217 C221 C227 I254 K257 V258I217-L223 HydrophobicContact CG2-CD2 3.58Å; C221-L223 PolarHBondContact O-N 3.29Å; L223-C227 VanDerWaalsContact O-CB 3.22Å; L223-C227 WeakPolarHBondContact O-CB 3.34Å; L223-C227 PolarHBondContact O-N 3.47Å; L223-C227 PolarHBondContact O-SG 2.95Å; L223-I254 HydrophobicContact CD1-CB 4.22Å; L223-I254 HydrophobicContact CD1-CG2 4.24Å; L223-I254 HydrophobicContact CD2-CD1 4.18Å; L223-K257 HydrophobicContact CD1-CB 3.92Å; L223-K257 HydrophobicContact CD1-CD 4.04Å; L223-V258 HydrophobicContact CD2-CG2 4.18Å
224I97.9Very high97.6Very high135 Ų13539.3 Ų39.369%0.69219%0.187SC*.Hα-helixtrans-66.5-50.6179.2-62.2174.3000108.7D222 R228D222-I224 VanDerWaalsContact C-N 3.25Å; D222-I224 PolarHBondContact O-N 2.95Å; D222-I224 WeakPolarHBondContact OD1-CB 3.4Å; D222-I224 PolarHBondContact OD1-N 3.16Å; I224-R228 VanDerWaalsContact O-CB 3.29Å; I224-R228 WeakPolarHBondContact O-CB 3.45Å; I224-R228 PolarHBondContact O-N 3.17Å
225V98.6Very high97.6Very high55 Ų5539.3 Ų39.333%0.33319%0.187SC..Hα-helixtrans-64.6-42.5178.1175.50000111.2D222 R228 R229D222-V225 HydrophobicContact CB-CB 4.26Å; D222-V225 HydrophobicContact CB-CG2 4.36Å; D222-V225 PolarHBondContact O-N 3.38Å; D222-V225 PolarHBondContact OD1-N 3.18Å; D222-V225 VanDerWaalsContact OD1-N 3.1Å; D222-V225 WeakPolarHBondContact OD2-CG2 3.09Å; V225-R228 PolarHBondContact O-N 3.27Å; V225-R229 WeakPolarHBondContact O-CG 3.43Å; V225-R229 PolarHBondContact O-N 2.83Å; V225-R229 VanDerWaalsContact O-N 3.08Å
226A98.7Very high97.4Very high2 Ų240.8 Ų40.82%0.01719%0.193CC..Hα-helixtrans-61-53.617900000111.8D222 R228 R229 I230 F365D222-A226 WeakPolarHBondContact O-CB 3.27Å; D222-A226 PolarHBondContact O-N 2.9Å; A226-R228 VanDerWaalsContact C-N 3.25Å; A226-R228 PolarHBondContact O-N 2.84Å; A226-R229 PolarHBondContact O-N 3.4Å; A226-I230 WeakPolarHBondContact O-CB 3.3Å; A226-I230 WeakPolarHBondContact O-CD1 3.48Å; A226-I230 VanDerWaalsContact O-CG1 3.22Å; A226-I230 WeakPolarHBondContact O-CG1 3.42Å; A226-I230 PolarHBondContact O-N 2.86Å; A226-F365 HydrophobicContact CB-CB 4.19Å; A226-F365 HydrophobicContact CB-CD1 3.43Å; A226-F365 VanDerWaalsContact CB-CD1 3.43Å; A226-F365 HydrophobicContact CB-CE1 4Å; A226-F365 HydrophobicContact CB-CG 3.92Å
227C98.7Very high97.3Very high1 Ų141.3 Ų41.31%0.00720%0.196CC..Hα-helixtrans-58.1-40.3178.2-73.40000111.7L223 I230 T231 V258 I262L223-C227 VanDerWaalsContact O-CB 3.22Å; L223-C227 WeakPolarHBondContact O-CB 3.34Å; L223-C227 PolarHBondContact O-N 3.47Å; L223-C227 PolarHBondContact O-SG 2.95Å; C227-I230 PolarHBondContact O-N 3.14Å; C227-T231 VanDerWaalsContact O-CB 3.26Å; C227-T231 WeakPolarHBondContact O-CB 3.4Å; C227-T231 PolarHBondContact O-N 3.45Å; C227-T231 PolarHBondContact O-OG1 3.19Å; C227-V258 VanDerWaalsContact SG-CA 3.6Å; C227-V258 PolarHBondContact SG-O 3.44Å; C227-V258 VanDerWaalsContact SG-O 3.37Å; C227-I262 HydrophobicContact CB-CG1 4.24Å
228R98.8Very high97.2Very high95 Ų9541.3 Ų41.336%0.35820%0.196SC..Hα-helixtrans-61.9-48.7179.6-168.2-176.717074.8-2.4112.5I224 V225 A226 T231 W232 T265 E268 F269I224-R228 VanDerWaalsContact O-CB 3.29Å; I224-R228 WeakPolarHBondContact O-CB 3.45Å; I224-R228 PolarHBondContact O-N 3.17Å; V225-R228 PolarHBondContact O-N 3.27Å; A226-R228 VanDerWaalsContact C-N 3.25Å; A226-R228 PolarHBondContact O-N 2.84Å; R228-T231 PolarHBondContact O-N 2.99Å; R228-W232 PolarHBondContact O-N 3.37Å; R228-W232 VanDerWaalsContact O-N 3.08Å; R228-T265 HydrophobicContact CB-CG2 4.35Å; R228-T265 HydrophobicContact CG-CG2 3.9Å; R228-E268 IonicContact CZ-OE1 2.97Å; R228-E268 IonicContact CZ-OE2 3.39Å; R228-E268 IonicContact NH1-OE1 2.71Å; R228-E268 PolarHBondContact NH1-OE1 3.32Å; R228-E268 IonicContact NH1-OE2 2.71Å; R228-E268 PolarHBondContact NH1-OE2 3.08Å; R228-E268 IonicContact NH2-OE1 3.25Å; R228-E268 PolarHBondContact NH2-OE1 3.26Å; R228-F269 HydrophobicContact CG-CZ 4.07Å
229R98.9Very high97.2Very high93 Ų9341 Ų4135%0.35120%0.195SC..Hα-helixtrans-63.8-44.5177.1-73.9174.9164.2153.97.8112.2V225 A226 T231 W232 G233 F365 N387 D388 V389V225-R229 WeakPolarHBondContact O-CG 3.43Å; V225-R229 PolarHBondContact O-N 2.83Å; V225-R229 VanDerWaalsContact O-N 3.08Å; A226-R229 PolarHBondContact O-N 3.4Å; R229-T231 PolarHBondContact O-N 2.71Å; R229-W232 PolarHBondContact O-N 2.83Å; R229-G233 PolarHBondContact O-N 3.44Å; R229-F365 HydrophobicContact CB-CE1 4.16Å; R229-F365 HydrophobicContact CB-CZ 4.16Å; R229-N387 WeakPolarHBondContact CD-O 3.37Å; R229-N387 PolarHBondContact NH1-O 2.76Å; R229-D388 WeakPolarHBondContact CD-OD1 3.25Å; R229-D388 IonicContact CZ-OD2 3.6Å; R229-D388 IonicContact NE-OD1 3.97Å; R229-D388 IonicContact NE-OD2 2.64Å; R229-D388 PolarHBondContact NE-OD2 2.64Å; R229-V389 VanDerWaalsContact O-CG2 3.23Å; R229-V389 WeakPolarHBondContact O-CG2 3.39Å
230I98.9Very high97.5Very high0 Ų036.3 Ų36.30%017%0.174CC..Hα-helixtrans-63.9-42.1178.4-66165.3000110.9C215 I217 A226 C227 G233 K234 P245 I248 L338 F365 V389C215-I230 WeakPolarHBondContact SG-CD1 3.25Å; I217-I230 HydrophobicContact CD1-CD1 3.5Å; I217-I230 VanDerWaalsContact CD1-CD1 3.5Å; I217-I230 HydrophobicContact CG1-CD1 3.88Å; A226-I230 WeakPolarHBondContact O-CB 3.3Å; A226-I230 WeakPolarHBondContact O-CD1 3.48Å; A226-I230 VanDerWaalsContact O-CG1 3.22Å; A226-I230 WeakPolarHBondContact O-CG1 3.42Å; A226-I230 PolarHBondContact O-N 2.86Å; C227-I230 PolarHBondContact O-N 3.14Å; I230-G233 PolarHBondContact O-N 2.95Å; I230-K234 VanDerWaalsContact O-CB 3.23Å; I230-K234 WeakPolarHBondContact O-CB 3.38Å; I230-K234 PolarHBondContact O-N 2.91Å; I230-P245 HydrophobicContact CG2-CB 4.37Å; I230-P245 HydrophobicContact CG2-CG 4.08Å; I230-I248 HydrophobicContact CG2-CD1 4.1Å; I230-I248 HydrophobicContact CG2-CG1 4.47Å; I230-L338 HydrophobicContact CG2-CD2 4.22Å; I230-F365 HydrophobicContact CD1-CD2 3.9Å; I230-F365 HydrophobicContact CD1-CE2 3.72Å; I230-F365 HydrophobicContact CD1-CG 4.49Å; I230-F365 HydrophobicContact CD1-CZ 4.15Å; I230-F365 HydrophobicContact CG1-CD2 4.23Å; I230-F365 HydrophobicContact CG1-CE1 4.49Å; I230-F365 HydrophobicContact CG1-CE2 3.51Å; I230-F365 HydrophobicContact CG1-CZ 3.67Å; I230-V389 HydrophobicContact CG1-CG1 4.34Å
231T98.9Very high97.9Very high0 Ų032.1 Ų32.10%015%0.152CC..Hα-helixtrans-61.9-46.5178.4-58.40000110.4C227 R228 R229 K234 F235 T265 L266 F269C227-T231 VanDerWaalsContact O-CB 3.26Å; C227-T231 WeakPolarHBondContact O-CB 3.4Å; C227-T231 PolarHBondContact O-N 3.45Å; C227-T231 PolarHBondContact O-OG1 3.19Å; R228-T231 PolarHBondContact O-N 2.99Å; R229-T231 PolarHBondContact O-N 2.71Å; T231-K234 PolarHBondContact O-N 3.32Å; T231-F235 HydrophobicContact CG2-CD2 3.67Å; T231-F235 HydrophobicContact CG2-CE2 4.04Å; T231-F235 WeakPolarHBondContact O-CD2 3.49Å; T231-F235 PolarHBondContact O-N 3.2Å; T231-T265 HydrophobicContact CG2-CG2 3.69Å; T231-L266 HydrophobicContact CG2-CD2 3.64Å; T231-L266 HydrophobicContact CG2-CG 3.77Å; T231-F269 HydrophobicContact CG2-CD2 4.17Å; T231-F269 HydrophobicContact CG2-CE2 4.24Å
232W98.6Very high98.1Very high89 Ų8932 Ų3234%0.33715%0.151SC..Hα-helixtrans-55.3-56.4174.1167.675.6000110.9R228 R229 K234 F235 F236 F269 V389 I390 M391R228-W232 PolarHBondContact O-N 3.37Å; R228-W232 VanDerWaalsContact O-N 3.08Å; R229-W232 PolarHBondContact O-N 2.83Å; W232-K234 VanDerWaalsContact C-N 3.31Å; W232-K234 PolarHBondContact O-N 2.99Å; W232-F235 PolarHBondContact O-N 3.48Å; W232-F236 WeakPolarHBondContact O-CB 3.3Å; W232-F236 PolarHBondContact O-N 2.96Å; W232-F269 HydrophobicContact CB-CE2 3.83Å; W232-F269 HydrophobicContact CB-CZ 4.32Å; W232-V389 HydrophobicContact CE3-CG2 3.84Å; W232-V389 HydrophobicContact CZ3-CG2 3.93Å; W232-I390 HydrophobicContact CH2-CB 3.96Å; W232-I390 HydrophobicContact CH2-CD1 4.17Å; W232-I390 HydrophobicContact CH2-CG2 4.11Å; W232-I390 HydrophobicContact CZ3-CB 3.94Å; W232-I390 HydrophobicContact CZ3-CD1 4.11Å; W232-I390 HydrophobicContact CZ3-CG1 4.34Å; W232-M391 HydrophobicContact CH2-SD 4.16Å; W232-M391 HydrophobicContact CZ3-SD 4.49Å
233G98.3Very high98.2Very high0 Ų027.9 Ų27.90%013%0.13CC..Hα-helixtrans-66.4-30.2-176.400000114.3R229 I230R229-G233 PolarHBondContact O-N 3.44Å; I230-G233 PolarHBondContact O-N 2.95Å
234K98.8Very high98.3Very high1 Ų126.8 Ų26.80%0.00412%0.124CC..Hα-helixtrans-71.9-46.4178.8176.357.4179.6-175.60112.3I230 T231 W232 G239 P245 G335 L337 L338I230-K234 VanDerWaalsContact O-CB 3.23Å; I230-K234 WeakPolarHBondContact O-CB 3.38Å; I230-K234 PolarHBondContact O-N 2.91Å; T231-K234 PolarHBondContact O-N 3.32Å; W232-K234 VanDerWaalsContact C-N 3.31Å; W232-K234 PolarHBondContact O-N 2.99Å; K234-G239 WeakPolarHBondContact O-CA 3.45Å; K234-G239 PolarHBondContact O-N 2.95Å; K234-P245 HydrophobicContact CB-CG 4Å; K234-P245 VanDerWaalsContact CD-O 3.26Å; K234-P245 WeakPolarHBondContact CD-O 3.19Å; K234-G335 WeakPolarHBondContact CE-O 3.48Å; K234-G335 PolarHBondContact NZ-O 3.05Å; K234-G335 VanDerWaalsContact NZ-O 3.15Å; K234-L337 WeakPolarHBondContact CE-O 3.3Å; K234-L337 PolarHBondContact NZ-O 2.96Å; K234-L338 HydrophobicContact CB-CD2 4.43Å; K234-L338 HydrophobicContact CD-CB 4.35Å; K234-L338 HydrophobicContact CD-CD1 4.07Å; K234-L338 HydrophobicContact CG-CB 4.11Å; K234-L338 HydrophobicContact CG-CD1 4.24Å; K234-L338 HydrophobicContact CG-CD2 4.15Å; K234-L338 HydrophobicContact CG-CG 4.41Å
235F98.3Very high98.3Very high2 Ų220.3 Ų20.31%0.0099%0.091CC..Hα-helixtrans-99.3-8.3-169.5-59.7-69.3000112.7T231 W232 N237 V238 I262 L266 Y270 Y280 P316 P336 L338T231-F235 HydrophobicContact CG2-CD2 3.67Å; T231-F235 HydrophobicContact CG2-CE2 4.04Å; T231-F235 WeakPolarHBondContact O-CD2 3.49Å; T231-F235 PolarHBondContact O-N 3.2Å; W232-F235 PolarHBondContact O-N 3.48Å; F235-N237 PolarHBondContact O-N 3.22Å; F235-V238 WeakPolarHBondContact O-CA 3.48Å; F235-V238 PolarHBondContact O-N 3.03Å; F235-I262 HydrophobicContact CE2-CG2 4.25Å; F235-L266 HydrophobicContact CD2-CD2 3.6Å; F235-L266 HydrophobicContact CE2-CD1 4.18Å; F235-L266 HydrophobicContact CE2-CD2 3.84Å; F235-L266 HydrophobicContact CE2-CG 4.34Å; F235-L266 HydrophobicContact CG-CD2 4.08Å; F235-L266 HydrophobicContact CZ-CD1 4.44Å; F235-Y270 HydrophobicContact CB-CE2 3.97Å; F235-Y280 HydrophobicContact CB-CE2 4.42Å; F235-P316 HydrophobicContact CD1-CB 3.67Å; F235-P316 HydrophobicContact CD1-CG 4.3Å; F235-P316 VanDerWaalsContact CE1-CA 3.45Å; F235-P316 HydrophobicContact CE1-CB 3.53Å; F235-P316 HydrophobicContact CE2-CB 4.39Å; F235-P316 HydrophobicContact CG-CB 4.17Å; F235-P316 HydrophobicContact CZ-CB 3.91Å; F235-P336 HydrophobicContact CD1-CB 3.83Å; F235-P336 HydrophobicContact CE1-CB 4.06Å; F235-P336 WeakPolarHBondContact CE1-O 3.36Å; F235-L338 HydrophobicContact CZ-CB 4.37Å
236F94.6Very high98.3Very high31 Ų3118 Ų1814%0.1368%0.077CC..G310 helixtrans-54.4130.6163.6-176.7-115.9000110.7S60 Y114 W232 V238 G239S60-F236 VanDerWaalsContact CB-CZ 3.47Å; Y114-F236 AromaticContact CE1-CE1 3.89Å; Y114-F236 HydrophobicContact CE1-CE1 3.89Å; Y114-F236 HydrophobicContact CE1-CZ 4.45Å; Y114-F236 AromaticContact CZ-CE1 3.93Å; Y114-F236 WeakPolarHBondContact OH-CD1 3.38Å; Y114-F236 WeakPolarHBondContact OH-CE1 3.42Å; W232-F236 WeakPolarHBondContact O-CB 3.3Å; W232-F236 PolarHBondContact O-N 2.96Å; F236-V238 PolarHBondContact O-N 3.13Å; F236-V238 VanDerWaalsContact O-N 3.16Å; F236-G239 PolarHBondContact O-N 3.23Å
237N97.1Very high98.3Very high12 Ų1218.1 Ų18.16%0.0648%0.077CC..G310 helixtrans50.535.3-172.8-161.941.8000113.4R52 N113 Y114 F235 G239 Q240R52-N237 PolarHBondContact NH2-ND2 3.43Å; R52-N237 PolarHBondContact NH2-OD1 3.13Å; N113-N237 PolarHBondContact O-ND2 3.44Å; Y114-N237 HydrophobicContact CE1-CB 4.44Å; Y114-N237 WeakPolarHBondContact OH-CB 3.49Å; F235-N237 PolarHBondContact O-N 3.22Å; N237-G239 PolarHBondContact O-N 3.14Å; N237-G239 VanDerWaalsContact O-N 3.09Å; N237-Q240 PolarHBondContact ND2-O 2.99Å; N237-Q240 VanDerWaalsContact ND2-O 3.17Å; N237-Q240 WeakPolarHBondContact O-CB 3.48Å; N237-Q240 PolarHBondContact O-N 3Å
238V97.8Very high98.3Very high1 Ų118 Ų181%0.0068%0.077CC..G310 helixtrans54.528.8-178.4-106.10000113F235 F236 Q240 Y280 R282 G335 P336F235-V238 WeakPolarHBondContact O-CA 3.48Å; F235-V238 PolarHBondContact O-N 3.03Å; F236-V238 PolarHBondContact O-N 3.13Å; F236-V238 VanDerWaalsContact O-N 3.16Å; V238-Q240 PolarHBondContact O-N 3.46Å; V238-Y280 HydrophobicContact CG1-CD1 4.18Å; V238-Y280 HydrophobicContact CG1-CD2 4.29Å; V238-Y280 HydrophobicContact CG1-CE1 3.54Å; V238-Y280 HydrophobicContact CG1-CE2 3.66Å; V238-Y280 WeakPolarHBondContact CG1-OH 3.46Å; V238-R282 WeakPolarHBondContact CG2-O 3.38Å; V238-G335 CarbonylContact O-C 3.48Å; V238-G335 WeakPolarHBondContact O-CA 3.22Å; V238-P336 HydrophobicContact CG1-CB 4.33Å; V238-P336 HydrophobicContact CG1-CG 4.26Å; V238-P336 WeakPolarHBondContact O-CD 3.47Å; V238-P336 VanDerWaalsContact O-N 3.08Å
239G98.1Very high98.3Very high1 Ų113.5 Ų13.51%0.016%0.06CC..G310 helixtrans71.711.1-178.500000115K234 F236 N237 T241 F334 G335K234-G239 WeakPolarHBondContact O-CA 3.45Å; K234-G239 PolarHBondContact O-N 2.95Å; F236-G239 PolarHBondContact O-N 3.23Å; N237-G239 PolarHBondContact O-N 3.14Å; N237-G239 VanDerWaalsContact O-N 3.09Å; G239-T241 PolarHBondContact O-N 3.26Å; G239-F334 CarbonylContact O-C 3.57Å; G239-F334 WeakPolarHBondContact O-CA 3.29Å; G239-G335 PolarHBondContact O-N 2.92Å; G239-G335 VanDerWaalsContact O-N 3.15Å
240Q98.6Very high98.3Very high0 Ų09.1 Ų9.10%04%0.043CC..  trans-81.360.2174.9-59.6176119.400110.3W112 N113 N237 V238 R282 I283 F334W112-Q240 HydrophobicContact CH2-CB 4.09Å; W112-Q240 HydrophobicContact CH2-CG 4.13Å; W112-Q240 HydrophobicContact CZ3-CB 4Å; W112-Q240 HydrophobicContact CZ3-CG 4.2Å; N113-Q240 HydrophobicContact CB-CB 4.43Å; N113-Q240 WeakPolarHBondContact CB-O 3.2Å; N113-Q240 PolarHBondContact ND2-O 3.22Å; N237-Q240 PolarHBondContact ND2-O 2.99Å; N237-Q240 VanDerWaalsContact ND2-O 3.17Å; N237-Q240 WeakPolarHBondContact O-CB 3.48Å; N237-Q240 PolarHBondContact O-N 3Å; V238-Q240 PolarHBondContact O-N 3.46Å; Q240-R282 PolarHBondContact NE2-O 3.45Å; Q240-I283 HydrophobicContact CG-CD1 4.36Å; Q240-F334 HydrophobicContact CB-CD1 3.82Å; Q240-F334 HydrophobicContact CB-CE1 3.72Å; Q240-F334 HydrophobicContact CG-CD1 4.2Å
241T98.5Very high98.2Very high10 Ų1010.4 Ų10.46%0.0615%0.049CC..  trans-143.3124.2-171.9-53.50000109.6Y114 G239 I243 A244Y114-T241 HydrophobicContact CE2-CG2 3.89Å; Y114-T241 PolarHBondContact OH-OG1 2.82Å; G239-T241 PolarHBondContact O-N 3.26Å; T241-I243 HydrophobicContact CG2-CG1 3.78Å; T241-I243 PolarHBondContact O-N 3.44Å; T241-I243 VanDerWaalsContact O-N 3.1Å; T241-A244 WeakPolarHBondContact O-CB 3.48Å; T241-A244 PolarHBondContact O-N 2.63Å
242C98.2Very high98.1Very high20 Ų2014.1 Ų14.114%0.1357%0.073CC..THydrogen-bonded Turntrans-59.9-27-176.1-48.90000113S213 L360S213-C242 PolarHBondContact OG-O 2.77Å; C242-L360 HydrophobicContact CB-CD2 3.68Å
243I98.6Very high98Very high9 Ų913.7 Ų13.75%0.0468%0.084CC..THydrogen-bonded Turntrans-104.412176.859.8175.5000113.2T241 L360 A361 Y363 I390 Y393 F400T241-I243 HydrophobicContact CG2-CG1 3.78Å; T241-I243 PolarHBondContact O-N 3.44Å; T241-I243 VanDerWaalsContact O-N 3.1Å; I243-L360 HydrophobicContact CG2-CB 4.42Å; I243-L360 HydrophobicContact CG2-CD2 3.49Å; I243-L360 VanDerWaalsContact CG2-CD2 3.49Å; I243-L360 HydrophobicContact CG2-CG 3.73Å; I243-A361 HydrophobicContact CB-CB 4.17Å; I243-A361 HydrophobicContact CG2-CB 4.02Å; I243-Y363 VanDerWaalsContact O-CE2 3.32Å; I243-Y363 WeakPolarHBondContact O-CE2 3.39Å; I243-Y363 VanDerWaalsContact O-CZ 3.31Å; I243-Y363 PolarHBondContact O-OH 3.21Å; I243-I390 HydrophobicContact CD1-CB 4.38Å; I243-I390 HydrophobicContact CD1-CG1 4.45Å; I243-I390 HydrophobicContact CD1-CG2 3.93Å; I243-I390 HydrophobicContact CG1-CG1 4.34Å; I243-Y393 HydrophobicContact CD1-CD2 4.22Å; I243-Y393 HydrophobicContact CD1-CG 4.17Å; I243-F400 HydrophobicContact CD1-CE2 4.41Å; I243-F400 HydrophobicContact CG2-CE2 3.87Å; I243-F400 HydrophobicContact CG2-CZ 4.09Å
244A98.8Very high98Very high5 Ų514.1 Ų14.14%0.0419%0.086CC..SBendtrans-61.2145.5168.800000109.6S213 T241 D246S213-A244 WeakPolarHBondContact CB-O 3.21Å; T241-A244 WeakPolarHBondContact O-CB 3.48Å; T241-A244 PolarHBondContact O-N 2.63Å; A244-D246 PolarHBondContact O-N 2.61Å
245P98.8Very high97.9Very high0 Ų014.9 Ų14.90%09%0.09CC..  trans-58.8111.2166.726.3-32.8000108.1C215 I230 K234 Y363 V389C215-P245 HydrophobicContact CB-CB 4Å; I230-P245 HydrophobicContact CG2-CB 4.37Å; I230-P245 HydrophobicContact CG2-CG 4.08Å; K234-P245 HydrophobicContact CB-CG 4Å; K234-P245 VanDerWaalsContact CD-O 3.26Å; K234-P245 WeakPolarHBondContact CD-O 3.19Å; P245-Y363 HydrophobicContact CB-CD2 4.02Å; P245-Y363 HydrophobicContact CB-CE2 4.29Å; P245-V389 HydrophobicContact CG-CG1 4.36Å
246D98.8Very high97.9Very high7 Ų720.8 Ų20.84%0.03712%0.121CC..  trans-79.8-40.6-172.8-175.8-89.6000110.3K212 S213 A244 I333 P339K212-D246 HydrophobicContact CB-CB 4.18Å; K212-D246 WeakPolarHBondContact CB-OD1 3.4Å; K212-D246 WeakPolarHBondContact CE-OD1 3.4Å; K212-D246 WeakPolarHBondContact CG-OD1 3.44Å; K212-D246 IonicContact NZ-OD1 3.2Å; K212-D246 PolarHBondContact NZ-OD1 2.97Å; K212-D246 IonicContact NZ-OD2 3.97Å; S213-D246 PolarHBondContact O-N 3.41Å; A244-D246 PolarHBondContact O-N 2.61Å; D246-I333 WeakPolarHBondContact O-CD1 3.41Å; D246-I333 WeakPolarHBondContact OD2-CB 3.4Å; D246-I333 WeakPolarHBondContact OD2-CG1 3.38Å; D246-I333 PolarHBondContact OD2-N 3.26Å; D246-P339 WeakPolarHBondContact O-CD 3.27Å
247Y98.8Very high98.1Very high3 Ų325.8 Ų25.81%0.01214%0.143CC..EExtended strand (participates in β ladder)trans-147.5156.9177.365.6-84.2000112K212 P214 C215 L249 M329 P339 F352K212-Y247 HydrophobicContact CB-CD1 4.03Å; K212-Y247 HydrophobicContact CB-CE1 3.74Å; P214-Y247 HydrophobicContact CB-CE1 4.06Å; P214-Y247 HydrophobicContact CB-CE2 4.02Å; C215-Y247 WeakPolarHBondContact CB-O 3.15Å; C215-Y247 PolarHBondContact N-O 3.45Å; Y247-L249 HydrophobicContact CD2-CD2 4.21Å; Y247-L249 HydrophobicContact CD2-CG 4Å; Y247-L249 HydrophobicContact CE2-CD1 3.83Å; Y247-L249 HydrophobicContact CE2-CD2 3.9Å; Y247-L249 HydrophobicContact CE2-CG 3.64Å; Y247-M329 HydrophobicContact CD1-CE 4.08Å; Y247-M329 HydrophobicContact CD2-CE 3.77Å; Y247-M329 HydrophobicContact CE1-CE 4.43Å; Y247-M329 HydrophobicContact CE2-CE 4.11Å; Y247-M329 HydrophobicContact CG-CE 3.72Å; Y247-M329 HydrophobicContact CG-SD 4.35Å; Y247-P339 WeakPolarHBondContact CA-O 3.49Å; Y247-F352 HydrophobicContact CD2-CE1 4.39Å; Y247-F352 AromaticContact CE2-CD1 3.97Å; Y247-F352 HydrophobicContact CE2-CD1 3.97Å; Y247-F352 AromaticContact CE2-CE1 3.5Å; Y247-F352 HydrophobicContact CE2-CE1 3.5Å; Y247-F352 AromaticContact CZ-CE1 3.83Å
248I98.8Very high98.1Very high0 Ų025.2 Ų25.20%014%0.14CC..EExtended strand (participates in β ladder)trans-100.1140.1174.1-67.5170.5000110.4C215 I217 I230 C250 V258 I262 L338 P339 I340 V341C215-I248 HydrophobicContact CB-CG1 4.37Å; C215-I248 CarbonylContact O-C 3.54Å; C215-I248 VanDerWaalsContact O-CA 3.27Å; C215-I248 WeakPolarHBondContact O-CA 3.43Å; I217-I248 HydrophobicContact CD1-CD1 4.1Å; I217-I248 HydrophobicContact CD1-CG1 4.4Å; I217-I248 HydrophobicContact CD1-CG2 3.72Å; I217-I248 HydrophobicContact CG1-CG2 4.06Å; I230-I248 HydrophobicContact CG2-CD1 4.1Å; I230-I248 HydrophobicContact CG2-CG1 4.47Å; I248-C250 HydrophobicContact CG2-CB 4.16Å; I248-V258 HydrophobicContact CD1-CG1 3.91Å; I248-I262 HydrophobicContact CD1-CD1 4Å; I248-L338 HydrophobicContact CD1-CD1 4.4Å; I248-L338 HydrophobicContact CD1-CD2 3.91Å; I248-L338 HydrophobicContact CD1-CG 4.23Å; I248-L338 HydrophobicContact CG1-CD1 4.19Å; I248-P339 PolarHBondContact N-O 3.45Å; I248-I340 HydrophobicContact CB-CG1 4.22Å; I248-I340 HydrophobicContact CB-CG2 4.28Å; I248-I340 HydrophobicContact CD1-CD1 4.47Å; I248-I340 HydrophobicContact CD1-CG1 4.28Å; I248-I340 HydrophobicContact CG2-CG2 4.07Å; I248-V341 PolarHBondContact O-N 3Å
249L98.6Very high98.2Very high0 Ų025.6 Ų25.60%014%0.142CC..EExtended strand (participates in β ladder)trans-113.6124.8163.5-65.2169.7000109C215 Y216 I217 Y247 V341 V343 A349 F352 I353C215-L249 PolarHBondContact O-N 3Å; Y216-L249 WeakPolarHBondContact CA-O 3.18Å; Y216-L249 HydrophobicContact CD2-CB 4.01Å; Y216-L249 WeakPolarHBondContact CD2-O 3.48Å; I217-L249 PolarHBondContact N-O 3.49Å; Y247-L249 HydrophobicContact CD2-CD2 4.21Å; Y247-L249 HydrophobicContact CD2-CG 4Å; Y247-L249 HydrophobicContact CE2-CD1 3.83Å; Y247-L249 HydrophobicContact CE2-CD2 3.9Å; Y247-L249 HydrophobicContact CE2-CG 3.64Å; L249-V341 WeakPolarHBondContact CA-O 3.37Å; L249-V341 HydrophobicContact CD2-CB 3.93Å; L249-V341 HydrophobicContact CD2-CG1 4.08Å; L249-V343 HydrophobicContact CB-CG2 4.26Å; L249-V343 HydrophobicContact CD2-CG1 3.81Å; L249-A349 HydrophobicContact CD1-CB 4.17Å; L249-F352 HydrophobicContact CD1-CD1 3.98Å; L249-F352 HydrophobicContact CD2-CD1 3.8Å; L249-F352 HydrophobicContact CD2-CE1 4.04Å; L249-F352 HydrophobicContact CD2-CG 4.09Å; L249-F352 HydrophobicContact CG-CD1 4.47Å; L249-I353 HydrophobicContact CD1-CD1 4.05Å; L249-I353 HydrophobicContact CD1-CG1 3.85Å
250C97.9Very high98.2Very high0 Ų029.5 Ų29.50%016%0.16CC..EExtended strand (participates in β ladder)trans-151.4164.8178.1720000112.2I217 I248 I254 V341 T342 V343I217-C250 HydrophobicContact CB-CB 4.27Å; I248-C250 HydrophobicContact CG2-CB 4.16Å; C250-I254 HydrophobicContact CB-CD1 3.8Å; C250-I254 HydrophobicContact CB-CG1 3.9Å; C250-V341 PolarHBondContact N-O 3.49Å; C250-T342 CarbonylContact O-C 3.39Å; C250-T342 VanDerWaalsContact O-CA 3.22Å; C250-T342 WeakPolarHBondContact O-CA 3.49Å; C250-V343 PolarHBondContact O-N 3.17Å
251E97.4Very high98.2Very high27 Ų2730.3 Ų30.313%0.12617%0.169CC..  trans-66.9146.6170.7-70.8-177.2-14000111K219 S253 I254 Q255 V343K219-E251 VanDerWaalsContact NZ-CD 3.29Å; K219-E251 IonicContact NZ-OE1 3.98Å; K219-E251 PolarHBondContact NZ-OE1 3.25Å; K219-E251 IonicContact NZ-OE2 2.68Å; K219-E251 PolarHBondContact NZ-OE2 3.31Å; E251-S253 PolarHBondContact O-N 2.82Å; E251-S253 VanDerWaalsContact O-N 3.12Å; E251-I254 HydrophobicContact CB-CG1 4.46Å; E251-I254 VanDerWaalsContact O-CG1 3.29Å; E251-I254 WeakPolarHBondContact O-CG1 3.37Å; E251-I254 PolarHBondContact O-N 3.29Å; E251-I254 VanDerWaalsContact O-N 3.13Å; E251-Q255 PolarHBondContact O-N 3.38Å; E251-V343 WeakPolarHBondContact CA-O 3.4Å
252P96.9Very high98.2Very high78 Ų7829.9 Ų29.951%0.50617%0.166SC..Hα-helixtrans-53.3-33.4175.6-24.129.6000113.5I254 Q255 T342 V343P252-I254 PolarHBondContact O-N 2.74Å; P252-I254 VanDerWaalsContact O-N 3.17Å; P252-Q255 PolarHBondContact O-N 3.39Å; P252-T342 HydrophobicContact CB-CG2 4.34Å; P252-T342 HydrophobicContact CG-CG2 4.3Å; P252-V343 WeakPolarHBondContact CD-O 3.37Å
253S97.4Very high98.2Very high81 Ų8133.7 Ų33.757%0.56618%0.177SC*.Hα-helixtrans-62.1-21.4-178.260.70000114.4E251E251-S253 PolarHBondContact O-N 2.82Å; E251-S253 VanDerWaalsContact O-N 3.12Å
254I97.6Very high98.2Very high9 Ų937.6 Ų37.65%0.04620%0.198CC..Hα-helixtrans-113.4-7.1-178.462.3167000114I217 K219 L223 C250 E251 P252 N256 K257 V258I217-I254 HydrophobicContact CB-CD1 4.43Å; I217-I254 HydrophobicContact CG2-CD1 4.02Å; K219-I254 HydrophobicContact CB-CG2 4.13Å; L223-I254 HydrophobicContact CD1-CB 4.22Å; L223-I254 HydrophobicContact CD1-CG2 4.24Å; L223-I254 HydrophobicContact CD2-CD1 4.18Å; C250-I254 HydrophobicContact CB-CD1 3.8Å; C250-I254 HydrophobicContact CB-CG1 3.9Å; E251-I254 HydrophobicContact CB-CG1 4.46Å; E251-I254 VanDerWaalsContact O-CG1 3.29Å; E251-I254 WeakPolarHBondContact O-CG1 3.37Å; E251-I254 PolarHBondContact O-N 3.29Å; E251-I254 VanDerWaalsContact O-N 3.13Å; P252-I254 PolarHBondContact O-N 2.74Å; P252-I254 VanDerWaalsContact O-N 3.17Å; I254-N256 PolarHBondContact O-N 3.06Å; I254-K257 WeakPolarHBondContact O-CB 3.27Å; I254-K257 PolarHBondContact O-N 3.3Å; I254-V258 WeakPolarHBondContact O-CG2 3.44Å; I254-V258 PolarHBondContact O-N 3.33Å
255Q97.3Very high98.2Very high17 Ų1737.8 Ų37.88%0.07920%0.199CC..Hα-helixtrans-52.4-51.4-175.9-171.8-167.743.900112.6E251 P252 K257 V258 V259 T320 D321 I340 T342E251-Q255 PolarHBondContact O-N 3.38Å; P252-Q255 PolarHBondContact O-N 3.39Å; Q255-K257 VanDerWaalsContact C-N 3.32Å; Q255-K257 PolarHBondContact O-N 2.95Å; Q255-V258 WeakPolarHBondContact O-CB 3.48Å; Q255-V258 PolarHBondContact O-N 2.95Å; Q255-V258 VanDerWaalsContact O-N 3.14Å; Q255-V259 WeakPolarHBondContact O-CG2 3.29Å; Q255-V259 PolarHBondContact O-N 3.29Å; Q255-T320 HydrophobicContact CG-CG2 4.19Å; Q255-D321 PolarHBondContact NE2-OD1 3.13Å; Q255-I340 HydrophobicContact CG-CG2 3.98Å; Q255-T342 HydrophobicContact CB-CG2 4.25Å; Q255-T342 HydrophobicContact CG-CG2 4.21Å
256N97.5Very high98.2Very high125 Ų12538.4 Ų38.467%0.66820%0.202SC*.Hα-helixtrans-63.3-36.2-179.9-71.8-23.3000113I254 V258 V259 E260I254-N256 PolarHBondContact O-N 3.06Å; N256-V258 VanDerWaalsContact C-N 3.33Å; N256-V259 PolarHBondContact O-N 2.91Å; N256-E260 WeakPolarHBondContact O-CB 3.33Å; N256-E260 PolarHBondContact O-N 3.48Å
257K98.1Very high98.1Very high137 Ų13742.9 Ų42.960%0.59622%0.223SC*.Hα-helixtrans-67.8-37.3176.2-64.7-179.5-179.1176.30111.2L223 I254 Q255 E260 G261L223-K257 HydrophobicContact CD1-CB 3.92Å; L223-K257 HydrophobicContact CD1-CD 4.04Å; I254-K257 WeakPolarHBondContact O-CB 3.27Å; I254-K257 PolarHBondContact O-N 3.3Å; Q255-K257 VanDerWaalsContact C-N 3.32Å; Q255-K257 PolarHBondContact O-N 2.95Å; K257-E260 PolarHBondContact O-N 3.38Å; K257-G261 PolarHBondContact O-N 3.38Å
258V98.3Very high98.1Very high0 Ų048.4 Ų48.40%025%0.249CC..Hα-helixtrans-64.6-46.9176171.70000110.8I217 L223 C227 I248 I254 Q255 N256 E260 G261 I262 I340I217-V258 HydrophobicContact CD1-CG1 3.98Å; I217-V258 HydrophobicContact CD1-CG2 3.99Å; L223-V258 HydrophobicContact CD2-CG2 4.18Å; C227-V258 VanDerWaalsContact SG-CA 3.6Å; C227-V258 PolarHBondContact SG-O 3.44Å; C227-V258 VanDerWaalsContact SG-O 3.37Å; I248-V258 HydrophobicContact CD1-CG1 3.91Å; I254-V258 WeakPolarHBondContact O-CG2 3.44Å; I254-V258 PolarHBondContact O-N 3.33Å; Q255-V258 WeakPolarHBondContact O-CB 3.48Å; Q255-V258 PolarHBondContact O-N 2.95Å; Q255-V258 VanDerWaalsContact O-N 3.14Å; N256-V258 VanDerWaalsContact C-N 3.33Å; V258-E260 VanDerWaalsContact C-N 3.31Å; V258-E260 PolarHBondContact O-N 2.95Å; V258-G261 PolarHBondContact O-N 3.05Å; V258-I262 HydrophobicContact CG1-CD1 3.8Å; V258-I262 WeakPolarHBondContact O-CD1 3.48Å; V258-I262 VanDerWaalsContact O-CG1 3.3Å; V258-I262 WeakPolarHBondContact O-CG1 3.4Å; V258-I262 PolarHBondContact O-N 3.12Å; V258-I340 HydrophobicContact CG1-CD1 3.96Å
259V98.5Very high98.1Very high9 Ų951 Ų516%0.05526%0.26CS..Hα-helixtrans-56.7-46.7175.8173.20000110.9Q255 N256 I262 R263 T302 V318 T320 I340Q255-V259 WeakPolarHBondContact O-CG2 3.29Å; Q255-V259 PolarHBondContact O-N 3.29Å; N256-V259 PolarHBondContact O-N 2.91Å; V259-I262 PolarHBondContact O-N 3.11Å; V259-R263 PolarHBondContact O-N 3.45Å; V259-T302 HydrophobicContact CG1-CG2 3.99Å; V259-V318 HydrophobicContact CG2-CG1 4.28Å; V259-T320 HydrophobicContact CG2-CG2 3.58Å; V259-I340 HydrophobicContact CG2-CD1 3.72Å
260E98.4Very high98Very high83 Ų8352.1 Ų52.139%0.38827%0.265SS..Hα-helixtrans-69.2-38.1-178.7-170.151.4-144.600112.6N256 K257 V258 I262 R263 N264N256-E260 WeakPolarHBondContact O-CB 3.33Å; N256-E260 PolarHBondContact O-N 3.48Å; K257-E260 PolarHBondContact O-N 3.38Å; V258-E260 VanDerWaalsContact C-N 3.31Å; V258-E260 PolarHBondContact O-N 2.95Å; E260-I262 VanDerWaalsContact C-N 3.31Å; E260-I262 PolarHBondContact O-N 2.99Å; E260-R263 PolarHBondContact O-N 3.32Å; E260-R263 WeakPolarHBondContact OE2-CD 3.11Å; E260-R263 IonicContact OE2-NE 3.41Å; E260-R263 PolarHBondContact OE2-NE 3.01Å; E260-N264 PolarHBondContact O-N 3.31Å; E260-N264 PolarHBondContact O-ND2 2.97Å; E260-N264 PolarHBondContact OE1-ND2 3.29Å
261G98.6Very high98Very high17 Ų1753.2 Ų53.218%0.17528%0.275CS..Hα-helixtrans-61-39.2172.400000112.7K257 V258 T265K257-G261 PolarHBondContact O-N 3.38Å; V258-G261 PolarHBondContact O-N 3.05Å; G261-T265 WeakPolarHBondContact O-CB 3.46Å; G261-T265 PolarHBondContact O-N 3.48Å; G261-T265 VanDerWaalsContact O-N 3.11Å; G261-T265 PolarHBondContact O-OG1 2.92Å
262I98.8Very high97.8Very high1 Ų157.3 Ų57.31%0.00531%0.305CS..Hα-helixtrans-68.3-45.4175.3-67.1161.9000110.7C227 F235 I248 V258 V259 E260 N264 T265 L266 L303 V318 L338C227-I262 HydrophobicContact CB-CG1 4.24Å; F235-I262 HydrophobicContact CE2-CG2 4.25Å; I248-I262 HydrophobicContact CD1-CD1 4Å; V258-I262 HydrophobicContact CG1-CD1 3.8Å; V258-I262 WeakPolarHBondContact O-CD1 3.48Å; V258-I262 VanDerWaalsContact O-CG1 3.3Å; V258-I262 WeakPolarHBondContact O-CG1 3.4Å; V258-I262 PolarHBondContact O-N 3.12Å; V259-I262 PolarHBondContact O-N 3.11Å; E260-I262 VanDerWaalsContact C-N 3.31Å; E260-I262 PolarHBondContact O-N 2.99Å; I262-N264 PolarHBondContact O-N 3.18Å; I262-T265 PolarHBondContact O-N 3.22Å; I262-L266 HydrophobicContact CG2-CD1 3.77Å; I262-L266 HydrophobicContact CG2-CG 4.23Å; I262-L266 WeakPolarHBondContact O-CB 3.49Å; I262-L266 WeakPolarHBondContact O-CG 3.41Å; I262-L266 PolarHBondContact O-N 3.35Å; I262-L303 HydrophobicContact CG2-CD2 4.45Å; I262-V318 HydrophobicContact CG2-CG2 3.81Å; I262-L338 HydrophobicContact CD1-CD2 3.87Å
263R98.6Very high97.8Very high99 Ų9957 Ų5737%0.37430%0.299SS..Hα-helixtrans-54.2-50.7176.4-179.1-168.9-60.2-77.5-6.9111.6V259 E260 T265 L266 Q267 L303V259-R263 PolarHBondContact O-N 3.45Å; E260-R263 PolarHBondContact O-N 3.32Å; E260-R263 WeakPolarHBondContact OE2-CD 3.11Å; E260-R263 IonicContact OE2-NE 3.41Å; E260-R263 PolarHBondContact OE2-NE 3.01Å; R263-T265 VanDerWaalsContact C-N 3.32Å; R263-T265 PolarHBondContact O-N 2.71Å; R263-L266 PolarHBondContact O-N 2.97Å; R263-Q267 PolarHBondContact O-N 2.89Å; R263-L303 HydrophobicContact CB-CD1 4.47Å; R263-L303 HydrophobicContact CB-CD2 4.13Å; R263-L303 HydrophobicContact CG-CD1 4.16Å
264N98.6Very high97.8Very high92 Ų9254.3 Ų54.349%0.49228%0.279SS..Hα-helixtrans-63.6-40.1-179.3-72.4-50.2000111.9E260 I262 Q267 E268E260-N264 PolarHBondContact O-N 3.31Å; E260-N264 PolarHBondContact O-ND2 2.97Å; E260-N264 PolarHBondContact OE1-ND2 3.29Å; I262-N264 PolarHBondContact O-N 3.18Å; N264-Q267 PolarHBondContact O-N 3.37Å; N264-E268 PolarHBondContact O-N 3.06Å; N264-E268 VanDerWaalsContact O-N 3.11Å
265T98.7Very high97.7Very high9 Ų957 Ų576%0.05529%0.29CS..Hα-helixtrans-66.5-40.4176.7-54.60000111.9R228 T231 G261 I262 R263 Q267 E268 F269R228-T265 HydrophobicContact CB-CG2 4.35Å; R228-T265 HydrophobicContact CG-CG2 3.9Å; T231-T265 HydrophobicContact CG2-CG2 3.69Å; G261-T265 WeakPolarHBondContact O-CB 3.46Å; G261-T265 PolarHBondContact O-N 3.48Å; G261-T265 VanDerWaalsContact O-N 3.11Å; G261-T265 PolarHBondContact O-OG1 2.92Å; I262-T265 PolarHBondContact O-N 3.22Å; R263-T265 VanDerWaalsContact C-N 3.32Å; R263-T265 PolarHBondContact O-N 2.71Å; T265-Q267 PolarHBondContact O-N 3.29Å; T265-E268 WeakPolarHBondContact O-CB 3.41Å; T265-E268 PolarHBondContact O-N 3.4Å; T265-F269 HydrophobicContact CG2-CD1 4.12Å; T265-F269 HydrophobicContact CG2-CD2 3.74Å; T265-F269 HydrophobicContact CG2-CE1 3.76Å; T265-F269 HydrophobicContact CG2-CE2 3.33Å; T265-F269 HydrophobicContact CG2-CG 4.12Å; T265-F269 HydrophobicContact CG2-CZ 3.34Å; T265-F269 WeakPolarHBondContact O-CG 3.35Å; T265-F269 PolarHBondContact O-N 3.5Å
266L98.4Very high97.7Very high12 Ų1260.4 Ų60.46%0.06332%0.316CS..Hα-helixtrans-63-42.1177.4-75.6170.2000112.1T231 F235 I262 R263 E268 F269 Y270 L303 P316T231-L266 HydrophobicContact CG2-CD2 3.64Å; T231-L266 HydrophobicContact CG2-CG 3.77Å; F235-L266 HydrophobicContact CD2-CD2 3.6Å; F235-L266 HydrophobicContact CE2-CD1 4.18Å; F235-L266 HydrophobicContact CE2-CD2 3.84Å; F235-L266 HydrophobicContact CE2-CG 4.34Å; F235-L266 HydrophobicContact CG-CD2 4.08Å; F235-L266 HydrophobicContact CZ-CD1 4.44Å; I262-L266 HydrophobicContact CG2-CD1 3.77Å; I262-L266 HydrophobicContact CG2-CG 4.23Å; I262-L266 WeakPolarHBondContact O-CB 3.49Å; I262-L266 WeakPolarHBondContact O-CG 3.41Å; I262-L266 PolarHBondContact O-N 3.35Å; R263-L266 PolarHBondContact O-N 2.97Å; L266-E268 VanDerWaalsContact C-N 3.27Å; L266-E268 PolarHBondContact O-N 3.25Å; L266-F269 PolarHBondContact O-N 3.31Å; L266-Y270 HydrophobicContact CD2-CD2 3.77Å; L266-Y270 HydrophobicContact CD2-CE2 3.82Å; L266-Y270 PolarHBondContact O-N 2.87Å; L266-L303 HydrophobicContact CD1-CD2 3.54Å; L266-P316 HydrophobicContact CD1-CB 3.71Å; L266-P316 HydrophobicContact CD2-CB 3.49Å; L266-P316 VanDerWaalsContact CD2-CB 3.49Å; L266-P316 HydrophobicContact CD2-CG 3.84Å; L266-P316 HydrophobicContact CG-CB 4.23Å
267Q97.9Very high97.6Very high101 Ų10155 Ų5547%0.47229%0.289SS..Hα-helixtrans-60.1-38.6174.2-178.364.339.100111.6R263 N264 T265 G271R263-Q267 PolarHBondContact O-N 2.89Å; N264-Q267 PolarHBondContact O-N 3.37Å; T265-Q267 PolarHBondContact O-N 3.29Å; Q267-G271 WeakPolarHBondContact O-CA 3.48Å; Q267-G271 PolarHBondContact O-N 3.43Å
268E98.3Very high97.4Very high119 Ų11952.5 Ų52.556%0.55629%0.286SS*.Hα-helixtrans-69.4-45176.1-172-16913800112.4R228 N264 T265 L266R228-E268 IonicContact CZ-OE1 2.97Å; R228-E268 IonicContact CZ-OE2 3.39Å; R228-E268 IonicContact NH1-OE1 2.71Å; R228-E268 PolarHBondContact NH1-OE1 3.32Å; R228-E268 IonicContact NH1-OE2 2.71Å; R228-E268 PolarHBondContact NH1-OE2 3.08Å; R228-E268 IonicContact NH2-OE1 3.25Å; R228-E268 PolarHBondContact NH2-OE1 3.26Å; N264-E268 PolarHBondContact O-N 3.06Å; N264-E268 VanDerWaalsContact O-N 3.11Å; T265-E268 WeakPolarHBondContact O-CB 3.41Å; T265-E268 PolarHBondContact O-N 3.4Å; L266-E268 VanDerWaalsContact C-N 3.27Å; L266-E268 PolarHBondContact O-N 3.25Å
269F97.6Very high97.2Very high54 Ų5455.6 Ų55.624%0.23730%0.303CS..Hα-helixtrans-75-40.9-174.2-70.6-4.4000113.3R228 T231 W232 T265 L266R228-F269 HydrophobicContact CG-CZ 4.07Å; T231-F269 HydrophobicContact CG2-CD2 4.17Å; T231-F269 HydrophobicContact CG2-CE2 4.24Å; W232-F269 HydrophobicContact CB-CE2 3.83Å; W232-F269 HydrophobicContact CB-CZ 4.32Å; T265-F269 HydrophobicContact CG2-CD1 4.12Å; T265-F269 HydrophobicContact CG2-CD2 3.74Å; T265-F269 HydrophobicContact CG2-CE1 3.76Å; T265-F269 HydrophobicContact CG2-CE2 3.33Å; T265-F269 HydrophobicContact CG2-CG 4.12Å; T265-F269 HydrophobicContact CG2-CZ 3.34Å; T265-F269 WeakPolarHBondContact O-CG 3.35Å; T265-F269 PolarHBondContact O-N 3.5Å; L266-F269 PolarHBondContact O-N 3.31Å
270Y97.4Very high97.1Very high25 Ų2555.2 Ų55.210%0.09830%0.3CS..Hα-helixtrans-121.5-0.3-169.2-53.7-59.3000113.3F235 L266 Y280 P316F235-Y270 HydrophobicContact CB-CE2 3.97Å; L266-Y270 HydrophobicContact CD2-CD2 3.77Å; L266-Y270 HydrophobicContact CD2-CE2 3.82Å; L266-Y270 PolarHBondContact O-N 2.87Å; Y270-Y280 HydrophobicContact CD1-CD2 4.12Å; Y270-Y280 HydrophobicContact CD2-CD2 4.32Å; Y270-Y280 AromaticContact CE1-CD2 3.87Å; Y270-Y280 HydrophobicContact CE1-CD2 3.87Å; Y270-Y280 HydrophobicContact CE2-CD2 4.07Å; Y270-Y280 HydrophobicContact CE2-CE2 4.37Å; Y270-Y280 HydrophobicContact CG-CD2 4.34Å; Y270-Y280 AromaticContact CZ-CD2 3.84Å; Y270-P316 HydrophobicContact CD2-CG 4.36Å
271G97.1Very high97Very high22 Ų2251.6 Ų51.623%0.22729%0.285CS..  trans71.3-168.5-176.300000112.8Q267 D273Q267-G271 WeakPolarHBondContact O-CA 3.48Å; Q267-G271 PolarHBondContact O-N 3.43Å; G271-D273 VanDerWaalsContact C-N 3.27Å; G271-D273 PolarHBondContact O-N 2.94Å
272P94.9Very high97Very high114 Ų11452.3 Ų52.374%0.7428%0.283SS*.SBendtrans-72.8-18.3-177.630.1-34.7000113.7
273D96.3Very high97Very high72 Ų7252.5 Ų52.539%0.38528%0.283SS..  trans-129.891.3177.4173.829.4000110.5G271 K275 S276G271-D273 VanDerWaalsContact C-N 3.27Å; G271-D273 PolarHBondContact O-N 2.94Å; D273-K275 PolarHBondContact O-N 2.88Å; D273-K275 VanDerWaalsContact O-N 3.07Å; D273-K275 WeakPolarHBondContact OD1-CB 3.36Å; D273-K275 PolarHBondContact OD1-N 3.12Å; D273-K275 VanDerWaalsContact OD1-N 3.12Å; D273-S276 PolarHBondContact O-N 2.84Å; D273-S276 PolarHBondContact O-OG 3.34Å; D273-S276 VanDerWaalsContact O-OG 3.11Å; D273-S276 VanDerWaalsContact OD2-CB 3.3Å; D273-S276 WeakPolarHBondContact OD2-CB 3.48Å; D273-S276 PolarHBondContact OD2-N 2.88Å; D273-S276 PolarHBondContact OD2-OG 3.17Å
274P96.4Very high97Very high23 Ų2348.7 Ų48.715%0.14927%0.27CS..THydrogen-bonded Turntrans-59.5-19.5177.7-25.535000114.1S276 S277 Y280 P316P274-S276 VanDerWaalsContact C-N 3.35Å; P274-S277 PolarHBondContact O-N 2.86Å; P274-Y280 WeakPolarHBondContact O-CB 3.31Å; P274-P316 HydrophobicContact CB-CG 4.05Å; P274-P316 HydrophobicContact CG-CG 4.17Å
275K97Very high97Very high65 Ų6546.2 Ų46.228%0.28326%0.257SS..THydrogen-bonded Turntrans-65.5-38.9178.1-166.8178179.7-178.70111.8D273 R282 D308 Y313D273-K275 PolarHBondContact O-N 2.88Å; D273-K275 VanDerWaalsContact O-N 3.07Å; D273-K275 WeakPolarHBondContact OD1-CB 3.36Å; D273-K275 PolarHBondContact OD1-N 3.12Å; D273-K275 VanDerWaalsContact OD1-N 3.12Å; K275-R282 PolarHBondContact O-NH2 2.98Å; K275-D308 VanDerWaalsContact CE-OD2 3.31Å; K275-D308 WeakPolarHBondContact CE-OD2 3.48Å; K275-D308 IonicContact NZ-OD2 2.67Å; K275-D308 PolarHBondContact NZ-OD2 3.21Å; K275-Y313 VanDerWaalsContact CA-CE2 3.41Å; K275-Y313 HydrophobicContact CB-CD1 4.31Å; K275-Y313 HydrophobicContact CB-CD2 4.22Å; K275-Y313 HydrophobicContact CB-CE1 3.86Å; K275-Y313 HydrophobicContact CB-CE2 3.75Å; K275-Y313 HydrophobicContact CB-CG 4.47Å; K275-Y313 HydrophobicContact CD-CD1 3.95Å; K275-Y313 HydrophobicContact CD-CE1 4.05Å; K275-Y313 HydrophobicContact CD-CG 4.41Å; K275-Y313 HydrophobicContact CG-CD1 3.85Å; K275-Y313 HydrophobicContact CG-CD2 4Å; K275-Y313 HydrophobicContact CG-CE1 3.91Å; K275-Y313 HydrophobicContact CG-CE2 4.05Å; K275-Y313 HydrophobicContact CG-CG 3.89Å; K275-Y313 PolarHBondContact N-OH 3.03Å
276S95.9Very high96.9Very high89 Ų8950.5 Ų50.562%0.62228%0.279SS*.THydrogen-bonded Turntrans-88.8-7.5179.855.40000114D273 P274D273-S276 PolarHBondContact O-N 2.84Å; D273-S276 PolarHBondContact O-OG 3.34Å; D273-S276 VanDerWaalsContact O-OG 3.11Å; D273-S276 VanDerWaalsContact OD2-CB 3.3Å; D273-S276 WeakPolarHBondContact OD2-CB 3.48Å; D273-S276 PolarHBondContact OD2-N 2.88Å; D273-S276 PolarHBondContact OD2-OG 3.17Å; P274-S276 VanDerWaalsContact C-N 3.35Å
277S95.9Very high96.9Very high13 Ų1359.8 Ų59.89%0.09131%0.313CS..  trans-62.4129.9176.5178.80000111.8P274 D279 Y280P274-S277 PolarHBondContact O-N 2.86Å; S277-D279 PolarHBondContact O-N 2.66Å; S277-D279 PolarHBondContact OG-N 3Å; S277-Y280 PolarHBondContact O-N 2.54Å
278P93.3Very high97Very high83 Ų8356.5 Ų56.554%0.53930%0.298SS..THydrogen-bonded Turntrans-69.3-20.1177.429.2-35.1000113.3
279D93.7Very high97Very high65 Ų6551.5 Ų51.535%0.34827%0.274SS..THydrogen-bonded Turntrans-96.72.7-176.1-55.5-49.6000112.6S53 S277S53-D279 WeakPolarHBondContact CB-OD1 3.31Å; S53-D279 PolarHBondContact OG-OD1 3.11Å; S277-D279 PolarHBondContact O-N 2.66Å; S277-D279 PolarHBondContact OG-N 3Å
280Y96.6Very high97.1Very high1 Ų152.1 Ų52.10%0.00429%0.285CS..  trans-102.2118.1175.1-161.2-110.8000111.4N51 F235 V238 Y270 P274 S277 R282 Y313 I314 P316 P336N51-Y280 PolarHBondContact ND2-O 3.1Å; F235-Y280 HydrophobicContact CB-CE2 4.42Å; V238-Y280 HydrophobicContact CG1-CD1 4.18Å; V238-Y280 HydrophobicContact CG1-CD2 4.29Å; V238-Y280 HydrophobicContact CG1-CE1 3.54Å; V238-Y280 HydrophobicContact CG1-CE2 3.66Å; V238-Y280 WeakPolarHBondContact CG1-OH 3.46Å; Y270-Y280 HydrophobicContact CD1-CD2 4.12Å; Y270-Y280 HydrophobicContact CD2-CD2 4.32Å; Y270-Y280 AromaticContact CE1-CD2 3.87Å; Y270-Y280 HydrophobicContact CE1-CD2 3.87Å; Y270-Y280 HydrophobicContact CE2-CD2 4.07Å; Y270-Y280 HydrophobicContact CE2-CE2 4.37Å; Y270-Y280 HydrophobicContact CG-CD2 4.34Å; Y270-Y280 AromaticContact CZ-CD2 3.84Å; P274-Y280 WeakPolarHBondContact O-CB 3.31Å; S277-Y280 PolarHBondContact O-N 2.54Å; Y280-R282 PolarHBondContact O-NH1 2.91Å; Y280-Y313 HydrophobicContact CD1-CD2 4.08Å; Y280-Y313 AromaticContact CD1-CE2 3.75Å; Y280-Y313 HydrophobicContact CD1-CE2 3.75Å; Y280-Y313 AromaticContact CE1-CD2 3.93Å; Y280-Y313 HydrophobicContact CE1-CD2 3.93Å; Y280-Y313 AromaticContact CE1-CE2 3.56Å; Y280-Y313 HydrophobicContact CE1-CE2 3.56Å; Y280-I314 VanDerWaalsContact CE1-O 3.28Å; Y280-I314 WeakPolarHBondContact CE1-O 3.4Å; Y280-I314 PolarHBondContact OH-O 2.99Å; Y280-P316 HydrophobicContact CD2-CG 4.49Å; Y280-P316 HydrophobicContact CE2-CG 3.68Å; Y280-P316 WeakPolarHBondContact OH-CD 3.42Å; Y280-P336 WeakPolarHBondContact OH-CB 3.39Å
281G96.6Very high97.1Very high7 Ų753.9 Ų53.97%0.07229%0.292CS..  trans-72.2-170-177.400000114.1L50L50-G281 WeakPolarHBondContact O-CA 2.97Å
282R98.2Very high97.2Very high33 Ų3352.9 Ų52.913%0.12528%0.281CS..  trans-127.8155.5173.4-63.5-59.6-178.9-962.2111.4L50 N51 V238 Q240 K275 Y280 Q311L50-R282 PolarHBondContact O-N 2.77Å; N51-R282 HydrophobicContact CB-CB 4.03Å; N51-R282 HydrophobicContact CB-CG 3.58Å; N51-R282 PolarHBondContact ND2-NH1 2.92Å; V238-R282 WeakPolarHBondContact CG2-O 3.38Å; Q240-R282 PolarHBondContact NE2-O 3.45Å; K275-R282 PolarHBondContact O-NH2 2.98Å; Y280-R282 PolarHBondContact O-NH1 2.91Å; R282-Q311 WeakPolarHBondContact CD-O 3.47Å; R282-Q311 WeakPolarHBondContact CG-O 3.36Å
283I98.8Very high97.3Very high4 Ų449.6 Ų49.62%0.02126%0.257CS..  trans-64.8135.8171.3-57.4-62.1000108.2Q240 N285 H288 F289 C312 I314Q240-I283 HydrophobicContact CG-CD1 4.36Å; I283-N285 PolarHBondContact O-N 3.47Å; I283-H288 HydrophobicContact CG2-CB 3.51Å; I283-F289 HydrophobicContact CB-CB 4.44Å; I283-F289 HydrophobicContact CG2-CB 4.21Å; I283-C312 HydrophobicContact CB-CB 4.2Å; I283-C312 WeakPolarHBondContact CB-O 3.48Å; I283-C312 PolarHBondContact N-O 2.99Å; I283-C312 WeakPolarHBondContact O-CB 3.5Å; I283-I314 HydrophobicContact CD1-CD1 4.26Å; I283-I314 HydrophobicContact CG1-CD1 3.81Å; I283-I314 HydrophobicContact CG1-CG1 4.06Å
284I98.6Very high97.4Very high19 Ų1946.6 Ų46.610%0.09724%0.243CC..SBendtrans-52.3-34.6-169.6-174.457.9000114.5D49 L50 W112 L140 H288D49-I284 VanDerWaalsContact O-CD1 3.28Å; D49-I284 WeakPolarHBondContact O-CD1 3.32Å; L50-I284 HydrophobicContact CD2-CB 4.36Å; L50-I284 HydrophobicContact CD2-CD1 3.78Å; L50-I284 HydrophobicContact CG-CD1 4.42Å; W112-I284 HydrophobicContact CD2-CB 4.39Å; W112-I284 HydrophobicContact CD2-CG1 4.13Å; W112-I284 HydrophobicContact CD2-CG2 4.27Å; W112-I284 HydrophobicContact CE3-CB 3.66Å; W112-I284 HydrophobicContact CE3-CD1 4.17Å; W112-I284 HydrophobicContact CE3-CG1 3.68Å; W112-I284 HydrophobicContact CE3-CG2 3.88Å; W112-I284 HydrophobicContact CH2-CB 4.1Å; W112-I284 HydrophobicContact CH2-CG2 3.55Å; W112-I284 HydrophobicContact CZ2-CG2 4Å; W112-I284 HydrophobicContact CZ3-CB 3.52Å; W112-I284 HydrophobicContact CZ3-CG1 4.1Å; W112-I284 HydrophobicContact CZ3-CG2 3.53Å; L140-I284 HydrophobicContact CB-CG1 4.12Å; L140-I284 WeakPolarHBondContact O-CD1 3.24Å; I284-H288 HydrophobicContact CG2-CB 3.86Å
285N98.4Very high97.5Very high41 Ų4145.5 Ų45.522%0.21924%0.236CC..SBendtrans-163174.2177.160.843000112I283 R287 H288 F289I283-N285 PolarHBondContact O-N 3.47Å; N285-R287 VanDerWaalsContact C-N 3.3Å; N285-R287 PolarHBondContact O-N 3.12Å; N285-R287 WeakPolarHBondContact OD1-CB 3.28Å; N285-R287 PolarHBondContact OD1-N 3.38Å; N285-R287 VanDerWaalsContact OD1-N 3.1Å; N285-H288 PolarHBondContact O-N 3.06Å; N285-H288 PolarHBondContact OD1-CD2 3.35Å; N285-H288 PolarHBondContact OD1-N 3.03Å; N285-F289 WeakPolarHBondContact O-CB 3.43Å; N285-F289 PolarHBondContact O-N 2.94Å
286L98.4Very high97.5Very high98 Ų9843.5 Ų43.551%0.51323%0.228SC..Hα-helixtrans-63.1-31.7-178.7-170.361.5000113.5F289 S290 P309L286-F289 HydrophobicContact CD1-CB 4.48Å; L286-F289 HydrophobicContact CD1-CD1 4Å; L286-F289 HydrophobicContact CD1-CG 4.46Å; L286-F289 WeakPolarHBondContact O-CB 3.3Å; L286-F289 PolarHBondContact O-N 3.3Å; L286-S290 PolarHBondContact O-N 2.94Å; L286-S290 PolarHBondContact O-OG 3.1Å; L286-S290 VanDerWaalsContact O-OG 3.11Å; L286-P309 HydrophobicContact CD1-CB 4.12Å
287R98.4Very high97.3Very high207 Ų20746.1 Ų46.178%0.78123%0.23SC*.Hα-helixtrans-64.1-47.7176.3176.8-174.6173.8-172.6-1111N285 R291N285-R287 VanDerWaalsContact C-N 3.3Å; N285-R287 PolarHBondContact O-N 3.12Å; N285-R287 WeakPolarHBondContact OD1-CB 3.28Å; N285-R287 PolarHBondContact OD1-N 3.38Å; N285-R287 VanDerWaalsContact OD1-N 3.1Å; R287-R291 WeakPolarHBondContact O-CB 3.36Å; R287-R291 PolarHBondContact O-N 3.29Å; R287-R291 VanDerWaalsContact O-N 3.08Å
288H98.6Very high96.9Very high33 Ų3349.6 Ų49.615%0.15327%0.268CS..Hα-helixtrans-68.3-37176.7-80.2-89.3000111.4W112 I283 I284 N285 R291 V292W112-H288 AromaticContact CZ2-CE1 3.71Å; I283-H288 HydrophobicContact CG2-CB 3.51Å; I284-H288 HydrophobicContact CG2-CB 3.86Å; N285-H288 PolarHBondContact O-N 3.06Å; N285-H288 PolarHBondContact OD1-CD2 3.35Å; N285-H288 PolarHBondContact OD1-N 3.03Å; H288-R291 PolarHBondContact O-N 3.39Å; H288-V292 VanDerWaalsContact O-CG2 3.29Å; H288-V292 WeakPolarHBondContact O-CG2 3.32Å; H288-V292 PolarHBondContact O-N 3.06Å
289F98.8Very high96.9Very high13 Ų1347 Ų476%0.05725%0.251CS..Hα-helixtrans-56.4-55.1174.1174.1-85.9000111.1I283 N285 L286 R291 V292 M293 P309 Y313 I314I283-F289 HydrophobicContact CB-CB 4.44Å; I283-F289 HydrophobicContact CG2-CB 4.21Å; N285-F289 WeakPolarHBondContact O-CB 3.43Å; N285-F289 PolarHBondContact O-N 2.94Å; L286-F289 HydrophobicContact CD1-CB 4.48Å; L286-F289 HydrophobicContact CD1-CD1 4Å; L286-F289 HydrophobicContact CD1-CG 4.46Å; L286-F289 WeakPolarHBondContact O-CB 3.3Å; L286-F289 PolarHBondContact O-N 3.3Å; F289-R291 VanDerWaalsContact C-N 3.31Å; F289-R291 PolarHBondContact O-N 3.08Å; F289-V292 PolarHBondContact O-N 3.46Å; F289-M293 HydrophobicContact CD1-CG 4.32Å; F289-M293 HydrophobicContact CE1-CG 3.87Å; F289-M293 HydrophobicContact CE2-CG 4.21Å; F289-M293 HydrophobicContact CZ-CG 3.82Å; F289-M293 WeakPolarHBondContact O-CG 3.45Å; F289-M293 PolarHBondContact O-N 3.39Å; F289-P309 HydrophobicContact CD1-CB 4.22Å; F289-P309 HydrophobicContact CE1-CB 3.63Å; F289-P309 HydrophobicContact CZ-CB 3.84Å; F289-Y313 WeakPolarHBondContact CE2-O 3.29Å; F289-I314 HydrophobicContact CD2-CD1 3.95Å; F289-I314 HydrophobicContact CD2-CG1 3.68Å; F289-I314 HydrophobicContact CE2-CD1 4.23Å; F289-I314 HydrophobicContact CE2-CG1 3.61Å
290S98.6Very high96.7Very high67 Ų6748.3 Ų48.347%0.46927%0.266SS..Hα-helixtrans-62.6-38.3-179.3-610000112.1L286 G294L286-S290 PolarHBondContact O-N 2.94Å; L286-S290 PolarHBondContact O-OG 3.1Å; L286-S290 VanDerWaalsContact O-OG 3.11Å; S290-G294 PolarHBondContact O-N 3.49Å
291R98.4Very high96.8Very high63 Ų6351 Ų5124%0.23828%0.282CS..Hα-helixtrans-59.9-50.3174.6-178.3-166.765.387.25.1111.3R287 H288 F289 G294 L295 E332 I333R287-R291 WeakPolarHBondContact O-CB 3.36Å; R287-R291 PolarHBondContact O-N 3.29Å; R287-R291 VanDerWaalsContact O-N 3.08Å; H288-R291 PolarHBondContact O-N 3.39Å; F289-R291 VanDerWaalsContact C-N 3.31Å; F289-R291 PolarHBondContact O-N 3.08Å; R291-G294 PolarHBondContact O-N 3.03Å; R291-L295 PolarHBondContact O-N 3.22Å; R291-E332 PolarHBondContact NH1-O 3.31Å; R291-I333 PolarHBondContact NH1-O 2.86Å; R291-I333 VanDerWaalsContact NH1-O 3.16Å; R291-I333 PolarHBondContact NH2-O 2.91Å
292V98.7Very high96.8Very high0 Ų053 Ų530%029%0.294CS..Hα-helixtrans-65.4-46.4-177.41740000110.5H288 F289 G294 L295 I314 L337H288-V292 VanDerWaalsContact O-CG2 3.29Å; H288-V292 WeakPolarHBondContact O-CG2 3.32Å; H288-V292 PolarHBondContact O-N 3.06Å; F289-V292 PolarHBondContact O-N 3.46Å; V292-G294 VanDerWaalsContact C-N 3.29Å; V292-G294 PolarHBondContact O-N 2.95Å; V292-L295 VanDerWaalsContact O-CB 3.29Å; V292-L295 WeakPolarHBondContact O-CB 3.22Å; V292-L295 PolarHBondContact O-N 3.39Å; V292-I314 HydrophobicContact CB-CD1 3.79Å; V292-I314 HydrophobicContact CG1-CD1 3.57Å; V292-L337 HydrophobicContact CG1-CD1 3.66Å; V292-L337 HydrophobicContact CG1-CD2 4.28Å; V292-L337 HydrophobicContact CG1-CG 3.77Å; V292-L337 WeakPolarHBondContact O-CD1 3.45Å
293M98.3Very high96.8Very high45 Ų4552.7 Ų52.722%0.22229%0.294CS..Hα-helixtrans-60.4-39.1176.7-71-56-61.500112.3F289 L295 L296 S307 I314F289-M293 HydrophobicContact CD1-CG 4.32Å; F289-M293 HydrophobicContact CE1-CG 3.87Å; F289-M293 HydrophobicContact CE2-CG 4.21Å; F289-M293 HydrophobicContact CZ-CG 3.82Å; F289-M293 WeakPolarHBondContact O-CG 3.45Å; F289-M293 PolarHBondContact O-N 3.39Å; M293-L295 PolarHBondContact O-N 2.88Å; M293-L295 VanDerWaalsContact O-N 3.16Å; M293-L296 HydrophobicContact CE-CD1 4.2Å; M293-L296 WeakPolarHBondContact O-CB 3.4Å; M293-L296 PolarHBondContact O-N 2.82Å; M293-L296 HydrophobicContact SD-CD1 4.43Å; M293-S307 WeakPolarHBondContact CE-OG 3.36Å; M293-I314 HydrophobicContact CG-CD1 3.84Å; M293-I314 HydrophobicContact CG-CG1 4.26Å; M293-I314 HydrophobicContact SD-CB 4.45Å; M293-I314 HydrophobicContact SD-CD1 3.76Å; M293-I314 HydrophobicContact SD-CG1 3.83Å; M293-I314 HydrophobicContact SD-CG2 3.86Å
294G97.8Very high96.7Very high9 Ų953.8 Ų53.89%0.09331%0.306CS..Hα-helixtrans-63.4-16175.200000114.5S290 R291 V292 L296S290-G294 PolarHBondContact O-N 3.49Å; R291-G294 PolarHBondContact O-N 3.03Å; V292-G294 VanDerWaalsContact C-N 3.29Å; V292-G294 PolarHBondContact O-N 2.95Å; G294-L296 VanDerWaalsContact C-N 3.26Å; G294-L296 PolarHBondContact O-N 3.48Å
295L98Very high96.6Very high1 Ų154 Ų541%0.00531%0.313CS..THydrogen-bonded Turntrans-72.7-20.3172.7-59.7177.4000112.6R291 V292 M293 E297 R327 L328 E331 I333 L337R291-L295 PolarHBondContact O-N 3.22Å; V292-L295 VanDerWaalsContact O-CB 3.29Å; V292-L295 WeakPolarHBondContact O-CB 3.22Å; V292-L295 PolarHBondContact O-N 3.39Å; M293-L295 PolarHBondContact O-N 2.88Å; M293-L295 VanDerWaalsContact O-N 3.16Å; L295-E297 VanDerWaalsContact C-N 3.32Å; L295-R327 HydrophobicContact CD2-CB 4.17Å; L295-L328 HydrophobicContact CB-CB 4.49Å; L295-L328 HydrophobicContact CB-CD1 3.95Å; L295-L328 HydrophobicContact CD1-CD1 4.43Å; L295-E331 HydrophobicContact CD2-CB 4.44Å; L295-I333 HydrophobicContact CD1-CB 4.48Å; L295-I333 HydrophobicContact CD1-CG1 4.47Å; L295-I333 HydrophobicContact CD1-CG2 4.3Å; L295-L337 HydrophobicContact CB-CD1 4.07Å; L295-L337 HydrophobicContact CD1-CD1 4.48Å
296L96.4Very high96.6Very high22 Ų2257.7 Ų57.712%0.11533%0.329CS..THydrogen-bonded Turntrans-82.3-8.6178.6-65.2177.4000113.2M293 G294 G298 C299 V301 T317 V319 L337M293-L296 HydrophobicContact CE-CD1 4.2Å; M293-L296 WeakPolarHBondContact O-CB 3.4Å; M293-L296 PolarHBondContact O-N 2.82Å; M293-L296 HydrophobicContact SD-CD1 4.43Å; G294-L296 VanDerWaalsContact C-N 3.26Å; G294-L296 PolarHBondContact O-N 3.48Å; L296-G298 PolarHBondContact O-N 2.69Å; L296-C299 WeakPolarHBondContact O-CB 3.34Å; L296-C299 PolarHBondContact O-N 3.32Å; L296-V301 HydrophobicContact CD1-CG2 4.49Å; L296-V301 HydrophobicContact CD2-CG2 4.28Å; L296-T317 HydrophobicContact CD1-CG2 4.45Å; L296-T317 HydrophobicContact CD2-CG2 4.3Å; L296-V319 HydrophobicContact CD2-CG2 3.79Å; L296-L337 HydrophobicContact CD1-CD1 4.47Å; L296-L337 HydrophobicContact CD1-CD2 3.99Å; L296-L337 HydrophobicContact CD2-CD1 3.83Å; L296-L337 HydrophobicContact CD2-CD2 4.09Å; L296-L337 HydrophobicContact CD2-CG 4.43Å; L296-L337 HydrophobicContact CG-CD1 3.84Å; L296-L337 HydrophobicContact CG-CD2 4.19Å
297E92.8Very high96.5Very high144 Ų14455.5 Ų55.567%0.67332%0.322SS*.THydrogen-bonded Turntrans-57.3124.6177.1-70.1174.8-171.700110.9L295 C299L295-E297 VanDerWaalsContact C-N 3.32Å; E297-C299 PolarHBondContact O-N 3.12Å
298G87.7Confident96.5Very high86 Ų8647 Ų4789%0.88729%0.292SS*.THydrogen-bonded Turntrans73.89-178.200000115.1L296L296-G298 PolarHBondContact O-N 2.69Å
299C92.8Very high96.5Very high28 Ų2848.8 Ų48.819%0.18931%0.307CS..PPolyproline II helixtrans-101.1150174.8-61.70000111.3L296 E297 V319L296-C299 WeakPolarHBondContact O-CB 3.34Å; L296-C299 PolarHBondContact O-N 3.32Å; E297-C299 PolarHBondContact O-N 3.12Å; C299-V319 HydrophobicContact CB-CG1 3.8Å
300S90.6Very high96.5Very high94 Ų9453 Ų5366%0.65734%0.338SS*.PPolyproline II helixtrans-96.8116.2171.9-167.90000109.9V319S300-V319 WeakPolarHBondContact O-CG1 3.43Å
301V97.2Very high96.3Very high57 Ų5754.2 Ų54.235%0.34534%0.336SS..EExtended strand (participates in β ladder)trans-81.7127.6-179.1176.80000110.2L296 L303 G304 T317L296-V301 HydrophobicContact CD1-CG2 4.49Å; L296-V301 HydrophobicContact CD2-CG2 4.28Å; V301-L303 VanDerWaalsContact CG1-O 3.32Å; V301-L303 WeakPolarHBondContact CG1-O 3.44Å; V301-G304 WeakPolarHBondContact CG1-O 3.45Å; V301-T317 HydrophobicContact CG1-CG2 3.76Å; V301-T317 HydrophobicContact CG2-CG2 4.27Å
302T97.6Very high96.3Very high50 Ų5052.2 Ų52.231%0.30733%0.332SS..EExtended strand (participates in β ladder)trans-97-32.5-177.6-40.60000112.1V259 V318 T320V259-T302 HydrophobicContact CG1-CG2 3.99Å; T302-V318 PolarHBondContact N-O 3.27Å; T302-T320 HydrophobicContact CG2-CG2 4.04Å; T302-T320 WeakPolarHBondContact OG1-CB 3.43Å; T302-T320 WeakPolarHBondContact OG1-CG2 3.34Å; T302-T320 PolarHBondContact OG1-N 2.91Å; T302-T320 PolarHBondContact OG1-OG1 3.43Å
303L97.3Very high96.3Very high25 Ų2552.7 Ų52.713%0.13133%0.334CS..EExtended strand (participates in β ladder)trans-143.8138.2177.5179.567.3000109.1I262 R263 L266 V301 T317 V318I262-L303 HydrophobicContact CG2-CD2 4.45Å; R263-L303 HydrophobicContact CB-CD1 4.47Å; R263-L303 HydrophobicContact CB-CD2 4.13Å; R263-L303 HydrophobicContact CG-CD1 4.16Å; L266-L303 HydrophobicContact CD1-CD2 3.54Å; V301-L303 VanDerWaalsContact CG1-O 3.32Å; V301-L303 WeakPolarHBondContact CG1-O 3.44Å; L303-T317 CarbonylContact O-C 3.11Å; L303-T317 VanDerWaalsContact O-CA 3.25Å; L303-T317 WeakPolarHBondContact O-CA 3.3Å; L303-V318 HydrophobicContact CB-CB 3.95Å; L303-V318 HydrophobicContact CB-CG2 4.23Å; L303-V318 HydrophobicContact CD2-CG2 3.99Å; L303-V318 PolarHBondContact N-O 3.34Å; L303-V318 PolarHBondContact O-N 3.1Å
304G97.4Very high96.4Very high27 Ų2750.6 Ų50.628%0.27832%0.323SS..  trans74.1-137.7177.600000112.7V301 E306V301-G304 WeakPolarHBondContact CG1-O 3.45Å; G304-E306 WeakPolarHBondContact CA-OE2 3.15Å
305G95.9Very high96.4Very high24 Ų2450.3 Ų50.325%0.24732%0.32CS..  trans94.7-7.8-177.600000114.5T317G305-T317 PolarHBondContact N-OG1 3.23Å; G305-T317 VanDerWaalsContact N-OG1 3.08Å
306E97.9Very high96.4Very high118 Ų11850.5 Ų50.555%0.55132%0.322SS*.  trans-67.4146.2173.1-55.381.7178.400111.1G304 A315G304-E306 WeakPolarHBondContact CA-OE2 3.15Å; E306-A315 HydrophobicContact CB-CB 4.09Å; E306-A315 VanDerWaalsContact O-CB 3.31Å; E306-A315 WeakPolarHBondContact O-CB 3.08Å; E306-A315 PolarHBondContact O-N 3.05Å; E306-A315 WeakPolarHBondContact OE2-CB 3.32Å
307S98.2Very high96.6Very high53 Ų5349.5 Ų49.537%0.37132%0.316SS..EExtended strand (participates in β ladder)trans-150.1159.117863.40000112M293 Y313M293-S307 WeakPolarHBondContact CE-OG 3.36Å; S307-Y313 CarbonylContact C-O 3.45Å; S307-Y313 WeakPolarHBondContact CA-O 3.23Å; S307-Y313 WeakPolarHBondContact CB-O 3.26Å
308D98.4Very high96.8Very high27 Ų2742.6 Ų42.614%0.14428%0.284CS..EExtended strand (participates in β ladder)trans-141.2105.2172.9-179.1-7.3000109.8K275 S310 Q311 C312 Y313K275-D308 VanDerWaalsContact CE-OD2 3.31Å; K275-D308 WeakPolarHBondContact CE-OD2 3.48Å; K275-D308 IonicContact NZ-OD2 2.67Å; K275-D308 PolarHBondContact NZ-OD2 3.21Å; D308-S310 VanDerWaalsContact CG-OG 3.31Å; D308-S310 PolarHBondContact O-N 2.78Å; D308-S310 WeakPolarHBondContact OD1-CB 3.45Å; D308-S310 PolarHBondContact OD1-N 2.7Å; D308-S310 PolarHBondContact OD1-OG 3.26Å; D308-S310 PolarHBondContact OD2-OG 2.95Å; D308-Q311 PolarHBondContact O-N 3.48Å; D308-C312 PolarHBondContact O-N 3.37Å; D308-C312 VanDerWaalsContact O-N 3.09Å; D308-Y313 HydrophobicContact CB-CD1 4.24Å; D308-Y313 PolarHBondContact N-O 3.09Å; D308-Y313 PolarHBondContact O-N 3.37Å
309P97.8Very high97.3Very high72 Ų7238.6 Ų38.647%0.46824%0.242SC..G310 helixtrans-64.9-27.5-17925-32.9000113L286 F289 Q311 C312L286-P309 HydrophobicContact CD1-CB 4.12Å; F289-P309 HydrophobicContact CD1-CB 4.22Å; F289-P309 HydrophobicContact CE1-CB 3.63Å; F289-P309 HydrophobicContact CZ-CB 3.84Å; P309-Q311 PolarHBondContact O-N 3.22Å; P309-C312 PolarHBondContact O-N 3.31Å
310S97.7Very high97.5Very high101 Ų10138 Ų3871%0.70624%0.238SC*.G310 helixtrans-67.3-23.5-179.574.40000112.7D308D308-S310 VanDerWaalsContact CG-OG 3.31Å; D308-S310 PolarHBondContact O-N 2.78Å; D308-S310 WeakPolarHBondContact OD1-CB 3.45Å; D308-S310 PolarHBondContact OD1-N 2.7Å; D308-S310 PolarHBondContact OD1-OG 3.26Å; D308-S310 PolarHBondContact OD2-OG 2.95Å
311Q96.4Very high97.2Very high92 Ų9239.1 Ų39.143%0.4324%0.236SC..G310 helixtrans-112.52.1177.5-60.8-170-16.600112.8R282 D308 P309 Y313R282-Q311 WeakPolarHBondContact CD-O 3.47Å; R282-Q311 WeakPolarHBondContact CG-O 3.36Å; D308-Q311 PolarHBondContact O-N 3.48Å; P309-Q311 PolarHBondContact O-N 3.22Å; Q311-Y313 PolarHBondContact O-N 2.91Å
312C98.4Very high96.8Very high22 Ų2236.9 Ų36.915%0.14922%0.223CC..THydrogen-bonded Turntrans50.238.2-168.5-65.30000112.7I283 D308 P309I283-C312 HydrophobicContact CB-CB 4.2Å; I283-C312 WeakPolarHBondContact CB-O 3.48Å; I283-C312 PolarHBondContact N-O 2.99Å; I283-C312 WeakPolarHBondContact O-CB 3.5Å; D308-C312 PolarHBondContact O-N 3.37Å; D308-C312 VanDerWaalsContact O-N 3.09Å; P309-C312 PolarHBondContact O-N 3.31Å
313Y98.7Very high96.4Very high9 Ų937.1 Ų37.14%0.03523%0.226CC..EExtended strand (participates in β ladder)trans-94.5128.3-178.7165.5-100.5000111.1K275 Y280 F289 S307 D308 Q311 A315K275-Y313 VanDerWaalsContact CA-CE2 3.41Å; K275-Y313 HydrophobicContact CB-CD1 4.31Å; K275-Y313 HydrophobicContact CB-CD2 4.22Å; K275-Y313 HydrophobicContact CB-CE1 3.86Å; K275-Y313 HydrophobicContact CB-CE2 3.75Å; K275-Y313 HydrophobicContact CB-CG 4.47Å; K275-Y313 HydrophobicContact CD-CD1 3.95Å; K275-Y313 HydrophobicContact CD-CE1 4.05Å; K275-Y313 HydrophobicContact CD-CG 4.41Å; K275-Y313 HydrophobicContact CG-CD1 3.85Å; K275-Y313 HydrophobicContact CG-CD2 4Å; K275-Y313 HydrophobicContact CG-CE1 3.91Å; K275-Y313 HydrophobicContact CG-CE2 4.05Å; K275-Y313 HydrophobicContact CG-CG 3.89Å; K275-Y313 PolarHBondContact N-OH 3.03Å; Y280-Y313 HydrophobicContact CD1-CD2 4.08Å; Y280-Y313 AromaticContact CD1-CE2 3.75Å; Y280-Y313 HydrophobicContact CD1-CE2 3.75Å; Y280-Y313 AromaticContact CE1-CD2 3.93Å; Y280-Y313 HydrophobicContact CE1-CD2 3.93Å; Y280-Y313 AromaticContact CE1-CE2 3.56Å; Y280-Y313 HydrophobicContact CE1-CE2 3.56Å; F289-Y313 WeakPolarHBondContact CE2-O 3.29Å; S307-Y313 CarbonylContact C-O 3.45Å; S307-Y313 WeakPolarHBondContact CA-O 3.23Å; S307-Y313 WeakPolarHBondContact CB-O 3.26Å; D308-Y313 HydrophobicContact CB-CD1 4.24Å; D308-Y313 PolarHBondContact N-O 3.09Å; D308-Y313 PolarHBondContact O-N 3.37Å; Q311-Y313 PolarHBondContact O-N 2.91Å; Y313-A315 HydrophobicContact CE1-CB 4.21Å; Y313-A315 WeakPolarHBondContact OH-CA 3.27Å; Y313-A315 VanDerWaalsContact OH-CB 3.32Å; Y313-A315 WeakPolarHBondContact OH-CB 3.41Å
314I98.8Very high95.9Very high1 Ų138.1 Ų38.11%0.00524%0.235CC..EExtended strand (participates in β ladder)trans-126.5125.9168.6-56.1178.1000107.1Y280 I283 F289 V292 M293 P336 L337Y280-I314 VanDerWaalsContact CE1-O 3.28Å; Y280-I314 WeakPolarHBondContact CE1-O 3.4Å; Y280-I314 PolarHBondContact OH-O 2.99Å; I283-I314 HydrophobicContact CD1-CD1 4.26Å; I283-I314 HydrophobicContact CG1-CD1 3.81Å; I283-I314 HydrophobicContact CG1-CG1 4.06Å; F289-I314 HydrophobicContact CD2-CD1 3.95Å; F289-I314 HydrophobicContact CD2-CG1 3.68Å; F289-I314 HydrophobicContact CE2-CD1 4.23Å; F289-I314 HydrophobicContact CE2-CG1 3.61Å; V292-I314 HydrophobicContact CB-CD1 3.79Å; V292-I314 HydrophobicContact CG1-CD1 3.57Å; M293-I314 HydrophobicContact CG-CD1 3.84Å; M293-I314 HydrophobicContact CG-CG1 4.26Å; M293-I314 HydrophobicContact SD-CB 4.45Å; M293-I314 HydrophobicContact SD-CD1 3.76Å; M293-I314 HydrophobicContact SD-CG1 3.83Å; M293-I314 HydrophobicContact SD-CG2 3.86Å; I314-P336 HydrophobicContact CB-CG 3.73Å; I314-P336 HydrophobicContact CG2-CG 3.77Å; I314-P336 WeakPolarHBondContact O-CG 3.46Å; I314-L337 HydrophobicContact CG2-CD2 4.11Å
315A98.6Very high95.5Very high3 Ų344.5 Ų44.53%0.02526%0.257CS..  trans-62.8151.9179.300000111.7E306 Y313 T317E306-A315 HydrophobicContact CB-CB 4.09Å; E306-A315 VanDerWaalsContact O-CB 3.31Å; E306-A315 WeakPolarHBondContact O-CB 3.08Å; E306-A315 PolarHBondContact O-N 3.05Å; E306-A315 WeakPolarHBondContact OE2-CB 3.32Å; Y313-A315 HydrophobicContact CE1-CB 4.21Å; Y313-A315 WeakPolarHBondContact OH-CA 3.27Å; Y313-A315 VanDerWaalsContact OH-CB 3.32Å; Y313-A315 WeakPolarHBondContact OH-CB 3.41Å; A315-T317 PolarHBondContact O-N 3.44Å; A315-T317 PolarHBondContact O-OG1 2.85Å
316P98.7Very high95.4Very high6 Ų644.8 Ų44.84%0.03925%0.254CS..  trans-53.9112.9168.4-24.334.3000110.5F235 L266 Y270 P274 Y280F235-P316 HydrophobicContact CD1-CB 3.67Å; F235-P316 HydrophobicContact CD1-CG 4.3Å; F235-P316 VanDerWaalsContact CE1-CA 3.45Å; F235-P316 HydrophobicContact CE1-CB 3.53Å; F235-P316 HydrophobicContact CE2-CB 4.39Å; F235-P316 HydrophobicContact CG-CB 4.17Å; F235-P316 HydrophobicContact CZ-CB 3.91Å; L266-P316 HydrophobicContact CD1-CB 3.71Å; L266-P316 HydrophobicContact CD2-CB 3.49Å; L266-P316 VanDerWaalsContact CD2-CB 3.49Å; L266-P316 HydrophobicContact CD2-CG 3.84Å; L266-P316 HydrophobicContact CG-CB 4.23Å; Y270-P316 HydrophobicContact CD2-CG 4.36Å; P274-P316 HydrophobicContact CB-CG 4.05Å; P274-P316 HydrophobicContact CG-CG 4.17Å; Y280-P316 HydrophobicContact CD2-CG 4.49Å; Y280-P316 HydrophobicContact CE2-CG 3.68Å; Y280-P316 WeakPolarHBondContact OH-CD 3.42Å
317T98.8Very high95.3Very high0 Ų044.6 Ų44.60%025%0.248CC..EExtended strand (participates in β ladder)trans-119.5130.7-168.4-59.10000110.9L296 V301 L303 G305 A315 V319 P336 L337 L338L296-T317 HydrophobicContact CD1-CG2 4.45Å; L296-T317 HydrophobicContact CD2-CG2 4.3Å; V301-T317 HydrophobicContact CG1-CG2 3.76Å; V301-T317 HydrophobicContact CG2-CG2 4.27Å; L303-T317 CarbonylContact O-C 3.11Å; L303-T317 VanDerWaalsContact O-CA 3.25Å; L303-T317 WeakPolarHBondContact O-CA 3.3Å; G305-T317 PolarHBondContact N-OG1 3.23Å; G305-T317 VanDerWaalsContact N-OG1 3.08Å; A315-T317 PolarHBondContact O-N 3.44Å; A315-T317 PolarHBondContact O-OG1 2.85Å; T317-V319 HydrophobicContact CG2-CG2 4.2Å; T317-P336 PolarHBondContact N-O 3.01Å; T317-L337 HydrophobicContact CG2-CD2 4.05Å; T317-L337 CarbonylContact O-C 3.49Å; T317-L337 WeakPolarHBondContact O-CA 3.3Å; T317-L338 PolarHBondContact O-N 3.26Å
318V98.7Very high95.3Very high0 Ų042.1 Ų42.10%023%0.231CC..EExtended strand (participates in β ladder)trans-115.5135172.6-177.80000109V259 I262 T302 L303 L338 I340V259-V318 HydrophobicContact CG2-CG1 4.28Å; I262-V318 HydrophobicContact CG2-CG2 3.81Å; T302-V318 PolarHBondContact N-O 3.27Å; L303-V318 HydrophobicContact CB-CB 3.95Å; L303-V318 HydrophobicContact CB-CG2 4.23Å; L303-V318 HydrophobicContact CD2-CG2 3.99Å; L303-V318 PolarHBondContact N-O 3.34Å; L303-V318 PolarHBondContact O-N 3.1Å; V318-L338 WeakPolarHBondContact CA-O 3.47Å; V318-L338 HydrophobicContact CG2-CB 4.49Å; V318-I340 HydrophobicContact CG1-CD1 3.72Å; V318-I340 HydrophobicContact CG1-CG1 4.05Å
319V98.3Very high95.2Very high1 Ų140.8 Ų40.81%0.00622%0.224CC..EExtended strand (participates in β ladder)trans-124120.3-179.1-169.60000107.9L296 C299 S300 T317 V322 L328 L338 P339 I340L296-V319 HydrophobicContact CD2-CG2 3.79Å; C299-V319 HydrophobicContact CB-CG1 3.8Å; S300-V319 WeakPolarHBondContact O-CG1 3.43Å; T317-V319 HydrophobicContact CG2-CG2 4.2Å; V319-V322 HydrophobicContact CB-CG2 3.85Å; V319-V322 HydrophobicContact CG1-CG2 3.45Å; V319-V322 VanDerWaalsContact CG1-CG2 3.45Å; V319-V322 WeakPolarHBondContact O-CG2 3.49Å; V319-L328 HydrophobicContact CB-CD2 4.11Å; V319-L328 HydrophobicContact CG1-CD2 4.17Å; V319-L328 HydrophobicContact CG2-CD2 4.04Å; V319-L338 PolarHBondContact N-O 3.16Å; V319-L338 VanDerWaalsContact N-O 3.12Å; V319-P339 CarbonylContact O-C 3.57Å; V319-P339 WeakPolarHBondContact O-CA 3.42Å; V319-I340 PolarHBondContact O-N 3.27Å
320T95.8Very high95.1Very high16 Ų1642.8 Ų42.810%0.09823%0.227CC..  trans-98.7167.5175.156.50000111.5Q255 V259 T302 V322 I340Q255-T320 HydrophobicContact CG-CG2 4.19Å; V259-T320 HydrophobicContact CG2-CG2 3.58Å; T302-T320 HydrophobicContact CG2-CG2 4.04Å; T302-T320 WeakPolarHBondContact OG1-CB 3.43Å; T302-T320 WeakPolarHBondContact OG1-CG2 3.34Å; T302-T320 PolarHBondContact OG1-N 2.91Å; T302-T320 PolarHBondContact OG1-OG1 3.43Å; T320-V322 PolarHBondContact O-N 3.02Å; T320-V322 VanDerWaalsContact O-N 3.13Å; T320-I340 HydrophobicContact CG2-CD1 4.37Å
321D84.7Confident94.9Very high117 Ų11741.4 Ų41.463%0.62621%0.209SC*.SBendtrans55.336.2174.2-49.2-44.6000113.2Q255 S323Q255-D321 PolarHBondContact NE2-OD1 3.13Å; D321-S323 PolarHBondContact O-N 2.88Å
322V88.8Confident95Very high10 Ų1039.4 Ų39.46%0.06120%0.2CC..  trans-76.7117.9-175.3-173.20000109.6V319 T320 T326 L328 M329 P339 V341V319-V322 HydrophobicContact CB-CG2 3.85Å; V319-V322 HydrophobicContact CG1-CG2 3.45Å; V319-V322 VanDerWaalsContact CG1-CG2 3.45Å; V319-V322 WeakPolarHBondContact O-CG2 3.49Å; T320-V322 PolarHBondContact O-N 3.02Å; T320-V322 VanDerWaalsContact O-N 3.13Å; V322-T326 HydrophobicContact CG1-CG2 4.49Å; V322-T326 WeakPolarHBondContact CG1-OG1 3.39Å; V322-L328 HydrophobicContact CG1-CD2 4.18Å; V322-L328 HydrophobicContact CG2-CD2 4.4Å; V322-M329 HydrophobicContact CG1-CG 3.6Å; V322-P339 HydrophobicContact CB-CB 4.28Å; V322-P339 HydrophobicContact CG1-CB 4.31Å; V322-P339 HydrophobicContact CG2-CB 3.8Å; V322-V341 HydrophobicContact CB-CG2 4.35Å
323S88.4Confident95Very high55 Ų5538.4 Ų38.439%0.38519%0.193SC..  trans-61.4133.8170167.50000110.1D321 H325 T326D321-S323 PolarHBondContact O-N 2.88Å; S323-H325 PolarHBondContact O-N 3.03Å; S323-H325 PolarHBondContact OG-N 3.43Å; S323-T326 WeakPolarHBondContact O-CG2 3.49Å; S323-T326 PolarHBondContact O-N 3.28Å; S323-T326 VanDerWaalsContact O-N 3.12Å; S323-T326 PolarHBondContact O-OG1 3.42Å
324P87.6Confident95Very high47 Ų4739 Ų3931%0.30520%0.196SC..THydrogen-bonded Turntrans-59.2-16.8177.6-25.935.7000114.4M329 Q330 F352P324-M329 WeakPolarHBondContact O-CB 3.19Å; P324-Q330 PolarHBondContact O-NE2 2.83Å; P324-F352 HydrophobicContact CB-CE2 3.86Å; P324-F352 HydrophobicContact CB-CZ 4.23Å; P324-F352 HydrophobicContact CG-CE2 3.77Å; P324-F352 HydrophobicContact CG-CZ 4.44Å
325H89.2Confident95Very high160 Ų16039 Ų3974%0.74120%0.195SC*.THydrogen-bonded Turntrans-90.9-5.8-178.1-57.9-64.3000114.1S323S323-H325 PolarHBondContact O-N 3.03Å; S323-H325 PolarHBondContact OG-N 3.43Å
326T94Very high95Very high31 Ų3138.8 Ų38.819%0.1919%0.194CC..SBendtrans-67.8154175.361.30000111.1V322 S323 L328 M329 Q330V322-T326 HydrophobicContact CG1-CG2 4.49Å; V322-T326 WeakPolarHBondContact CG1-OG1 3.39Å; S323-T326 WeakPolarHBondContact O-CG2 3.49Å; S323-T326 PolarHBondContact O-N 3.28Å; S323-T326 VanDerWaalsContact O-N 3.12Å; S323-T326 PolarHBondContact O-OG1 3.42Å; T326-L328 PolarHBondContact O-N 3.12Å; T326-M329 PolarHBondContact O-N 3.48Å; T326-Q330 WeakPolarHBondContact O-CG 3.17Å; T326-Q330 PolarHBondContact O-N 3.27Å
327R95.6Very high95Very high114 Ų11438.5 Ų38.543%0.4319%0.192SC..Hα-helixtrans-54.3-37.9175.3-68.6-176.661.5-152.9-5.3112.3L295 M329 Q330 E331L295-R327 HydrophobicContact CD2-CB 4.17Å; R327-M329 PolarHBondContact O-N 3.13Å; R327-M329 VanDerWaalsContact O-N 3.11Å; R327-Q330 PolarHBondContact O-N 2.88Å; R327-E331 IonicContact CZ-OE1 3.23Å; R327-E331 IonicContact NE-OE1 3.75Å; R327-E331 PolarHBondContact NE-OE1 3.11Å; R327-E331 IonicContact NH2-OE1 3.34Å; R327-E331 PolarHBondContact NH2-OE1 3.46Å; R327-E331 VanDerWaalsContact NH2-OE1 3.15Å; R327-E331 PolarHBondContact O-N 2.89Å; R327-E331 VanDerWaalsContact O-N 3.14Å
328L97.2Very high95Very high0 Ų038.5 Ų38.50%019%0.192CC..Hα-helixtrans-52.2-31.8174.3-172.960.1000113.3K212 L295 V319 V322 T326 I333 L337 P339K212-L328 PolarHBondContact NZ-O 3Å; L295-L328 HydrophobicContact CB-CB 4.49Å; L295-L328 HydrophobicContact CB-CD1 3.95Å; L295-L328 HydrophobicContact CD1-CD1 4.43Å; V319-L328 HydrophobicContact CB-CD2 4.11Å; V319-L328 HydrophobicContact CG1-CD2 4.17Å; V319-L328 HydrophobicContact CG2-CD2 4.04Å; V322-L328 HydrophobicContact CG1-CD2 4.18Å; V322-L328 HydrophobicContact CG2-CD2 4.4Å; T326-L328 PolarHBondContact O-N 3.12Å; L328-I333 HydrophobicContact CD1-CD1 3.79Å; L328-I333 HydrophobicContact CD1-CG1 4.05Å; L328-L337 HydrophobicContact CD1-CB 4.14Å; L328-L337 HydrophobicContact CD1-CD1 3.98Å; L328-P339 HydrophobicContact CD2-CB 3.86Å; L328-P339 HydrophobicContact CD2-CG 4.28Å; L328-P339 HydrophobicContact CG-CB 4.17Å; L328-P339 HydrophobicContact CG-CG 4.11Å
329M97.3Very high95Very high0 Ų038.5 Ų38.50%019%0.192CC..Hα-helixtrans-101.4-2.9179.7-71.7-55.1-60.100115K212 Y247 V322 P324 T326 R327 P339 V341 F352 K356K212-M329 WeakPolarHBondContact CD-O 3.1Å; K212-M329 WeakPolarHBondContact CE-O 3.27Å; Y247-M329 HydrophobicContact CD1-CE 4.08Å; Y247-M329 HydrophobicContact CD2-CE 3.77Å; Y247-M329 HydrophobicContact CE1-CE 4.43Å; Y247-M329 HydrophobicContact CE2-CE 4.11Å; Y247-M329 HydrophobicContact CG-CE 3.72Å; Y247-M329 HydrophobicContact CG-SD 4.35Å; V322-M329 HydrophobicContact CG1-CG 3.6Å; P324-M329 WeakPolarHBondContact O-CB 3.19Å; T326-M329 PolarHBondContact O-N 3.48Å; R327-M329 PolarHBondContact O-N 3.13Å; R327-M329 VanDerWaalsContact O-N 3.11Å; M329-P339 HydrophobicContact SD-CB 3.91Å; M329-P339 HydrophobicContact SD-CG 3.68Å; M329-V341 HydrophobicContact CE-CG2 3.92Å; M329-V341 HydrophobicContact CG-CG2 4.39Å; M329-V341 HydrophobicContact SD-CG2 4.01Å; M329-F352 HydrophobicContact CE-CE1 4.04Å; M329-F352 HydrophobicContact CE-CZ 3.84Å; M329-K356 PolarHBondContact O-NZ 2.9Å
330Q95.5Very high95Very high114 Ų11438.5 Ų38.553%0.53319%0.192SC..Hα-helixtrans-101.9-29.7180-64.5-59.6-50.700113.2P324 T326 R327P324-Q330 PolarHBondContact O-NE2 2.83Å; T326-Q330 WeakPolarHBondContact O-CG 3.17Å; T326-Q330 PolarHBondContact O-N 3.27Å; R327-Q330 PolarHBondContact O-N 2.88Å
331E94.4Very high95.1Very high71 Ų7138.1 Ų38.133%0.33219%0.19SC..SBendtrans-109.7154.1-179.4-58.3179.8-127.600111K212 L295 R327 I333K212-E331 WeakPolarHBondContact CD-O 3.23Å; K212-E331 PolarHBondContact NZ-O 2.89Å; L295-E331 HydrophobicContact CD2-CB 4.44Å; R327-E331 IonicContact CZ-OE1 3.23Å; R327-E331 IonicContact NE-OE1 3.75Å; R327-E331 PolarHBondContact NE-OE1 3.11Å; R327-E331 IonicContact NH2-OE1 3.34Å; R327-E331 PolarHBondContact NH2-OE1 3.46Å; R327-E331 VanDerWaalsContact NH2-OE1 3.15Å; R327-E331 PolarHBondContact O-N 2.89Å; R327-E331 VanDerWaalsContact O-N 3.14Å; E331-I333 PolarHBondContact O-N 3.13Å
332E97.9Very high95.6Very high51 Ų5135.1 Ų35.124%0.23818%0.176CC..  trans-64.2128.2167.5-177.5177.8-153.100109.7G210 G211 R291 F334G210-E332 WeakPolarHBondContact CA-OE1 3.46Å; G211-E332 VanDerWaalsContact N-CD 3.34Å; G211-E332 PolarHBondContact N-OE1 2.77Å; G211-E332 VanDerWaalsContact N-OE1 3.11Å; R291-E332 PolarHBondContact NH1-O 3.31Å; E332-F334 HydrophobicContact CG-CB 4.44Å; E332-F334 HydrophobicContact CG-CD2 4.36Å
333I98.6Very high96Very high0 Ų035.3 Ų35.30%018%0.177CC..  trans-71.3-52.5-170.9-61.6176.7000109.7D246 R291 L295 L328 E331 G335 L337 P339D246-I333 WeakPolarHBondContact O-CD1 3.41Å; D246-I333 WeakPolarHBondContact OD2-CB 3.4Å; D246-I333 WeakPolarHBondContact OD2-CG1 3.38Å; D246-I333 PolarHBondContact OD2-N 3.26Å; R291-I333 PolarHBondContact NH1-O 2.86Å; R291-I333 VanDerWaalsContact NH1-O 3.16Å; R291-I333 PolarHBondContact NH2-O 2.91Å; L295-I333 HydrophobicContact CD1-CB 4.48Å; L295-I333 HydrophobicContact CD1-CG1 4.47Å; L295-I333 HydrophobicContact CD1-CG2 4.3Å; L328-I333 HydrophobicContact CD1-CD1 3.79Å; L328-I333 HydrophobicContact CD1-CG1 4.05Å; E331-I333 PolarHBondContact O-N 3.13Å; I333-G335 VanDerWaalsContact C-N 3.27Å; I333-G335 PolarHBondContact O-N 3.43Å; I333-L337 VanDerWaalsContact CD1-O 3.25Å; I333-L337 WeakPolarHBondContact CD1-O 3.42Å; I333-L337 HydrophobicContact CG2-CB 3.8Å; I333-L337 HydrophobicContact CG2-CD1 4.33Å; I333-L337 HydrophobicContact CG2-CG 4.12Å; I333-P339 VanDerWaalsContact CD1-CD 3.4Å; I333-P339 HydrophobicContact CD1-CG 3.75Å
334F98.6Very high96.4Very high22 Ų2234.9 Ų34.910%0.09618%0.181CC..  trans4950.1-179.2-140.4-100.3000112.4W112 N113 G239 Q240 E332W112-F334 AromaticContact CH2-CD1 3.54Å; W112-F334 HydrophobicContact CH2-CD1 3.54Å; W112-F334 AromaticContact CH2-CE1 3.29Å; W112-F334 HydrophobicContact CH2-CE1 3.29Å; W112-F334 AromaticContact CZ2-CD1 3.73Å; W112-F334 HydrophobicContact CZ2-CD1 3.73Å; W112-F334 AromaticContact CZ2-CE1 3.4Å; W112-F334 HydrophobicContact CZ2-CE1 3.4Å; W112-F334 VanDerWaalsContact CZ2-CE1 3.4Å; W112-F334 HydrophobicContact CZ3-CE1 4.02Å; N113-F334 HydrophobicContact CB-CE1 3.95Å; N113-F334 HydrophobicContact CB-CZ 3.95Å; N113-F334 WeakPolarHBondContact ND2-CZ 3.33Å; G239-F334 CarbonylContact O-C 3.57Å; G239-F334 WeakPolarHBondContact O-CA 3.29Å; Q240-F334 HydrophobicContact CB-CD1 3.82Å; Q240-F334 HydrophobicContact CB-CE1 3.72Å; Q240-F334 HydrophobicContact CG-CD1 4.2Å; E332-F334 HydrophobicContact CG-CB 4.44Å; E332-F334 HydrophobicContact CG-CD2 4.36Å
335G98.6Very high96.9Very high0 Ų036.1 Ų36.10%019%0.185CC..SBendtrans-176.7173.2-170.800000111.3K234 V238 G239 I333 L337K234-G335 WeakPolarHBondContact CE-O 3.48Å; K234-G335 PolarHBondContact NZ-O 3.05Å; K234-G335 VanDerWaalsContact NZ-O 3.15Å; V238-G335 CarbonylContact O-C 3.48Å; V238-G335 WeakPolarHBondContact O-CA 3.22Å; G239-G335 PolarHBondContact O-N 2.92Å; G239-G335 VanDerWaalsContact O-N 3.15Å; I333-G335 VanDerWaalsContact C-N 3.27Å; I333-G335 PolarHBondContact O-N 3.43Å; G335-L337 PolarHBondContact O-N 2.93Å
336P98.6Very high97.3Very high0 Ų029.3 Ų29.30%016%0.155CC..SBendtrans-85.843-168.735.9-36.9000112.4F235 V238 Y280 I314 T317F235-P336 HydrophobicContact CD1-CB 3.83Å; F235-P336 HydrophobicContact CE1-CB 4.06Å; F235-P336 WeakPolarHBondContact CE1-O 3.36Å; V238-P336 HydrophobicContact CG1-CB 4.33Å; V238-P336 HydrophobicContact CG1-CG 4.26Å; V238-P336 WeakPolarHBondContact O-CD 3.47Å; V238-P336 VanDerWaalsContact O-N 3.08Å; Y280-P336 WeakPolarHBondContact OH-CB 3.39Å; I314-P336 HydrophobicContact CB-CG 3.73Å; I314-P336 HydrophobicContact CG2-CG 3.77Å; I314-P336 WeakPolarHBondContact O-CG 3.46Å; T317-P336 PolarHBondContact N-O 3.01Å
337L98.8Very high97.5Very high0 Ų028.2 Ų28.20%015%0.149CC..EExtended strand (participates in β ladder)trans-112.2121176-43.7-179.1000109.6K234 V292 L295 L296 I314 T317 L328 I333 G335 P339K234-L337 WeakPolarHBondContact CE-O 3.3Å; K234-L337 PolarHBondContact NZ-O 2.96Å; V292-L337 HydrophobicContact CG1-CD1 3.66Å; V292-L337 HydrophobicContact CG1-CD2 4.28Å; V292-L337 HydrophobicContact CG1-CG 3.77Å; V292-L337 WeakPolarHBondContact O-CD1 3.45Å; L295-L337 HydrophobicContact CB-CD1 4.07Å; L295-L337 HydrophobicContact CD1-CD1 4.48Å; L296-L337 HydrophobicContact CD1-CD1 4.47Å; L296-L337 HydrophobicContact CD1-CD2 3.99Å; L296-L337 HydrophobicContact CD2-CD1 3.83Å; L296-L337 HydrophobicContact CD2-CD2 4.09Å; L296-L337 HydrophobicContact CD2-CG 4.43Å; L296-L337 HydrophobicContact CG-CD1 3.84Å; L296-L337 HydrophobicContact CG-CD2 4.19Å; I314-L337 HydrophobicContact CG2-CD2 4.11Å; T317-L337 HydrophobicContact CG2-CD2 4.05Å; T317-L337 CarbonylContact O-C 3.49Å; T317-L337 WeakPolarHBondContact O-CA 3.3Å; L328-L337 HydrophobicContact CD1-CB 4.14Å; L328-L337 HydrophobicContact CD1-CD1 3.98Å; I333-L337 VanDerWaalsContact CD1-O 3.25Å; I333-L337 WeakPolarHBondContact CD1-O 3.42Å; I333-L337 HydrophobicContact CG2-CB 3.8Å; I333-L337 HydrophobicContact CG2-CD1 4.33Å; I333-L337 HydrophobicContact CG2-CG 4.12Å; G335-L337 PolarHBondContact O-N 2.93Å; L337-P339 WeakPolarHBondContact O-CD 3.43Å
338L98.8Very high97.7Very high0 Ų025.5 Ų25.50%014%0.144CC..EExtended strand (participates in β ladder)trans-116.693.1-177.9-173.557.8000110.7I230 K234 F235 I248 I262 T317 V318 V319I230-L338 HydrophobicContact CG2-CD2 4.22Å; K234-L338 HydrophobicContact CB-CD2 4.43Å; K234-L338 HydrophobicContact CD-CB 4.35Å; K234-L338 HydrophobicContact CD-CD1 4.07Å; K234-L338 HydrophobicContact CG-CB 4.11Å; K234-L338 HydrophobicContact CG-CD1 4.24Å; K234-L338 HydrophobicContact CG-CD2 4.15Å; K234-L338 HydrophobicContact CG-CG 4.41Å; F235-L338 HydrophobicContact CZ-CB 4.37Å; I248-L338 HydrophobicContact CD1-CD1 4.4Å; I248-L338 HydrophobicContact CD1-CD2 3.91Å; I248-L338 HydrophobicContact CD1-CG 4.23Å; I248-L338 HydrophobicContact CG1-CD1 4.19Å; I262-L338 HydrophobicContact CD1-CD2 3.87Å; T317-L338 PolarHBondContact O-N 3.26Å; V318-L338 WeakPolarHBondContact CA-O 3.47Å; V318-L338 HydrophobicContact CG2-CB 4.49Å; V319-L338 PolarHBondContact N-O 3.16Å; V319-L338 VanDerWaalsContact N-O 3.12Å
339P98.6Very high97.7Very high0 Ų025.5 Ų25.50%014%0.144CC..EExtended strand (participates in β ladder)trans-70.6140.3171.727.5-33.2000111.6D246 Y247 I248 V319 V322 L328 M329 I333 L337D246-P339 WeakPolarHBondContact O-CD 3.27Å; Y247-P339 WeakPolarHBondContact CA-O 3.49Å; I248-P339 PolarHBondContact N-O 3.45Å; V319-P339 CarbonylContact O-C 3.57Å; V319-P339 WeakPolarHBondContact O-CA 3.42Å; V322-P339 HydrophobicContact CB-CB 4.28Å; V322-P339 HydrophobicContact CG1-CB 4.31Å; V322-P339 HydrophobicContact CG2-CB 3.8Å; L328-P339 HydrophobicContact CD2-CB 3.86Å; L328-P339 HydrophobicContact CD2-CG 4.28Å; L328-P339 HydrophobicContact CG-CB 4.17Å; L328-P339 HydrophobicContact CG-CG 4.11Å; M329-P339 HydrophobicContact SD-CB 3.91Å; M329-P339 HydrophobicContact SD-CG 3.68Å; I333-P339 VanDerWaalsContact CD1-CD 3.4Å; I333-P339 HydrophobicContact CD1-CG 3.75Å; L337-P339 WeakPolarHBondContact O-CD 3.43Å
340I97.9Very high97.8Very high0 Ų025.8 Ų25.80%015%0.145CC..EExtended strand (participates in β ladder)trans-113.7116.4171.4-52.7-177.9000108.4I248 Q255 V258 V259 V318 V319 T320I248-I340 HydrophobicContact CB-CG1 4.22Å; I248-I340 HydrophobicContact CB-CG2 4.28Å; I248-I340 HydrophobicContact CD1-CD1 4.47Å; I248-I340 HydrophobicContact CD1-CG1 4.28Å; I248-I340 HydrophobicContact CG2-CG2 4.07Å; Q255-I340 HydrophobicContact CG-CG2 3.98Å; V258-I340 HydrophobicContact CG1-CD1 3.96Å; V259-I340 HydrophobicContact CG2-CD1 3.72Å; V318-I340 HydrophobicContact CG1-CD1 3.72Å; V318-I340 HydrophobicContact CG1-CG1 4.05Å; V319-I340 PolarHBondContact O-N 3.27Å; T320-I340 HydrophobicContact CG2-CD1 4.37Å
341V97.1Very high98Very high9 Ų927.8 Ų27.86%0.05515%0.148CC..EExtended strand (participates in β ladder)trans-107.2127.8177.3178.70000108.6I248 L249 C250 V322 M329 F352I248-V341 PolarHBondContact O-N 3Å; L249-V341 WeakPolarHBondContact CA-O 3.37Å; L249-V341 HydrophobicContact CD2-CB 3.93Å; L249-V341 HydrophobicContact CD2-CG1 4.08Å; C250-V341 PolarHBondContact N-O 3.49Å; V322-V341 HydrophobicContact CB-CG2 4.35Å; M329-V341 HydrophobicContact CE-CG2 3.92Å; M329-V341 HydrophobicContact CG-CG2 4.39Å; M329-V341 HydrophobicContact SD-CG2 4.01Å; V341-F352 HydrophobicContact CG1-CE2 4.12Å; V341-F352 HydrophobicContact CG1-CZ 4.3Å
342T96.8Very high98.2Very high53 Ų5326.4 Ų26.433%0.32514%0.141SC..EExtended strand (participates in β ladder)trans-85.7142.3179.353.80000111.6C250 P252 Q255C250-T342 CarbonylContact O-C 3.39Å; C250-T342 VanDerWaalsContact O-CA 3.22Å; C250-T342 WeakPolarHBondContact O-CA 3.49Å; P252-T342 HydrophobicContact CB-CG2 4.34Å; P252-T342 HydrophobicContact CG-CG2 4.3Å; Q255-T342 HydrophobicContact CB-CG2 4.25Å; Q255-T342 HydrophobicContact CG-CG2 4.21Å
343V97.2Very high98.2Very high14 Ų1424.3 Ų24.39%0.08513%0.131CC..  trans-135.1151.6178.5-70.20000109.7Y216 L249 C250 E251 P252 D348 A349Y216-V343 HydrophobicContact CE2-CG2 4.23Å; L249-V343 HydrophobicContact CB-CG2 4.26Å; L249-V343 HydrophobicContact CD2-CG1 3.81Å; C250-V343 PolarHBondContact O-N 3.17Å; E251-V343 WeakPolarHBondContact CA-O 3.4Å; P252-V343 WeakPolarHBondContact CD-O 3.37Å; V343-D348 HydrophobicContact CB-CB 3.9Å; V343-D348 HydrophobicContact CG1-CB 4.37Å; V343-A349 HydrophobicContact CG2-CB 4.16Å
344G97.1Very high98.2Very high46 Ų4628.5 Ų28.547%0.47415%0.154SC..SBendtrans-70.5-39.3-176.600000113.3D348G344-D348 VanDerWaalsContact CA-OD2 3.27Å; G344-D348 WeakPolarHBondContact CA-OD2 3.45Å; G344-D348 PolarHBondContact N-OD2 3.38Å
345D97.1Very high98.2Very high74 Ų7430.7 Ų30.740%0.39618%0.182SC..SBendtrans-158.2-176.1179.963.431.7000112.5G347 D348 A349D345-G347 PolarHBondContact O-N 3.31Å; D345-G347 WeakPolarHBondContact OD1-CA 3.36Å; D345-G347 PolarHBondContact OD1-N 2.93Å; D345-D348 PolarHBondContact O-N 2.95Å; D345-D348 PolarHBondContact OD1-N 2.91Å; D345-A349 PolarHBondContact O-N 3.07Å
346V98.1Very high98.1Very high17 Ų1733.4 Ų33.410%0.10319%0.194CC..Hα-helixtrans-59.1-32.5174.766.60000112.9Y216 A349 I350 V371 M375Y216-V346 HydrophobicContact CE1-CB 4.37Å; Y216-V346 HydrophobicContact CE1-CG2 4.23Å; Y216-V346 PolarHBondContact OH-N 2.99Å; V346-A349 WeakPolarHBondContact O-CB 3.46Å; V346-A349 PolarHBondContact O-N 2.88Å; V346-I350 HydrophobicContact CG2-CD1 4.07Å; V346-I350 WeakPolarHBondContact O-CD1 3.36Å; V346-I350 VanDerWaalsContact O-CG1 3.26Å; V346-I350 WeakPolarHBondContact O-CG1 3.26Å; V346-I350 PolarHBondContact O-N 3.37Å; V346-V371 HydrophobicContact CB-CG1 4.47Å; V346-V371 HydrophobicContact CG2-CG1 3.89Å; V346-M375 HydrophobicContact CG2-CE 3.85Å
347G98.6Very high98.1Very high7 Ų739.4 Ų39.47%0.07222%0.222CC..Hα-helixtrans-69.3-40.8178.100000112.2D345 I350 R351D345-G347 PolarHBondContact O-N 3.31Å; D345-G347 WeakPolarHBondContact OD1-CA 3.36Å; D345-G347 PolarHBondContact OD1-N 2.93Å; G347-I350 PolarHBondContact O-N 2.86Å; G347-R351 WeakPolarHBondContact O-CG 3.2Å; G347-R351 PolarHBondContact O-N 3.13Å; G347-R351 PolarHBondContact O-NH1 3.17Å
348D98.3Very high98.1Very high57 Ų5743.7 Ų43.731%0.30524%0.24SC..Hα-helixtrans-61.4-43.5170-79.2-30.4000111.5V343 G344 D345 I350 R351 F352V343-D348 HydrophobicContact CB-CB 3.9Å; V343-D348 HydrophobicContact CG1-CB 4.37Å; G344-D348 VanDerWaalsContact CA-OD2 3.27Å; G344-D348 WeakPolarHBondContact CA-OD2 3.45Å; G344-D348 PolarHBondContact N-OD2 3.38Å; D345-D348 PolarHBondContact O-N 2.95Å; D345-D348 PolarHBondContact OD1-N 2.91Å; D348-I350 PolarHBondContact O-N 3.23Å; D348-R351 PolarHBondContact O-N 2.99Å; D348-R351 IonicContact OD1-CZ 2.85Å; D348-R351 IonicContact OD1-NE 2.86Å; D348-R351 IonicContact OD1-NH2 3.67Å; D348-R351 PolarHBondContact OD1-NH2 3.31Å; D348-F352 WeakPolarHBondContact O-CB 3.37Å; D348-F352 PolarHBondContact O-N 3.35Å
349A98.6Very high98.1Very high0 Ų043.9 Ų43.90%024%0.242CC..Hα-helixtrans-59.3-46.5176.200000112Y216 L249 V343 D345 V346 R351 F352 I353 M375Y216-A349 HydrophobicContact CD2-CB 3.47Å; Y216-A349 VanDerWaalsContact CD2-CB 3.47Å; Y216-A349 HydrophobicContact CE2-CB 3.63Å; Y216-A349 HydrophobicContact CG-CB 4.31Å; L249-A349 HydrophobicContact CD1-CB 4.17Å; V343-A349 HydrophobicContact CG2-CB 4.16Å; D345-A349 PolarHBondContact O-N 3.07Å; V346-A349 WeakPolarHBondContact O-CB 3.46Å; V346-A349 PolarHBondContact O-N 2.88Å; A349-R351 PolarHBondContact O-N 3.01Å; A349-F352 WeakPolarHBondContact O-CB 3.46Å; A349-F352 PolarHBondContact O-N 2.89Å; A349-I353 VanDerWaalsContact O-CG1 3.27Å; A349-I353 WeakPolarHBondContact O-CG1 3.43Å; A349-I353 PolarHBondContact O-N 2.86Å; A349-M375 HydrophobicContact CB-CE 4.08Å
350I98.9Very high98.1Very high7 Ų744 Ų444%0.03624%0.243CC..Hα-helixtrans-60.3-46.3176.8-72163.5000110.7V346 G347 D348 F352 I353 N354 R374 M375 E378 T379V346-I350 HydrophobicContact CG2-CD1 4.07Å; V346-I350 WeakPolarHBondContact O-CD1 3.36Å; V346-I350 VanDerWaalsContact O-CG1 3.26Å; V346-I350 WeakPolarHBondContact O-CG1 3.26Å; V346-I350 PolarHBondContact O-N 3.37Å; G347-I350 PolarHBondContact O-N 2.86Å; D348-I350 PolarHBondContact O-N 3.23Å; I350-F352 VanDerWaalsContact C-N 3.32Å; I350-F352 PolarHBondContact O-N 2.66Å; I350-I353 PolarHBondContact O-N 3.08Å; I350-N354 WeakPolarHBondContact O-CB 3.27Å; I350-N354 PolarHBondContact O-N 2.91Å; I350-N354 PolarHBondContact O-ND2 3.39Å; I350-R374 HydrophobicContact CD1-CB 4.35Å; I350-M375 HydrophobicContact CD1-SD 4.43Å; I350-M375 HydrophobicContact CG1-CE 4.2Å; I350-M375 HydrophobicContact CG1-SD 3.55Å; I350-M375 VanDerWaalsContact CG1-SD 3.55Å; I350-E378 HydrophobicContact CD1-CB 4.15Å; I350-E378 HydrophobicContact CG2-CB 3.8Å; I350-T379 HydrophobicContact CB-CG2 4.49Å; I350-T379 HydrophobicContact CG1-CG2 4.22Å; I350-T379 HydrophobicContact CG2-CG2 4.17Å
351R98.8Very high98.1Very high156 Ų15644 Ų4459%0.58924%0.243SC*.Hα-helixtrans-60.3-42176-76.7-173.5-70.5-85.78.6111.9G347 D348 A349 N354 G355G347-R351 WeakPolarHBondContact O-CG 3.2Å; G347-R351 PolarHBondContact O-N 3.13Å; G347-R351 PolarHBondContact O-NH1 3.17Å; D348-R351 PolarHBondContact O-N 2.99Å; D348-R351 IonicContact OD1-CZ 2.85Å; D348-R351 IonicContact OD1-NE 2.86Å; D348-R351 IonicContact OD1-NH2 3.67Å; D348-R351 PolarHBondContact OD1-NH2 3.31Å; A349-R351 PolarHBondContact O-N 3.01Å; R351-N354 PolarHBondContact O-N 3.17Å; R351-G355 PolarHBondContact O-N 2.94Å
352F98.4Very high98.2Very high41 Ų4143.7 Ų43.718%0.1824%0.24CC..Hα-helixtrans-61.9-47.2178.4-172.5-84.4000111.9Y247 L249 P324 M329 V341 D348 A349 I350 G355 K356Y247-F352 HydrophobicContact CD2-CE1 4.39Å; Y247-F352 AromaticContact CE2-CD1 3.97Å; Y247-F352 HydrophobicContact CE2-CD1 3.97Å; Y247-F352 AromaticContact CE2-CE1 3.5Å; Y247-F352 HydrophobicContact CE2-CE1 3.5Å; Y247-F352 AromaticContact CZ-CE1 3.83Å; L249-F352 HydrophobicContact CD1-CD1 3.98Å; L249-F352 HydrophobicContact CD2-CD1 3.8Å; L249-F352 HydrophobicContact CD2-CE1 4.04Å; L249-F352 HydrophobicContact CD2-CG 4.09Å; L249-F352 HydrophobicContact CG-CD1 4.47Å; P324-F352 HydrophobicContact CB-CE2 3.86Å; P324-F352 HydrophobicContact CB-CZ 4.23Å; P324-F352 HydrophobicContact CG-CE2 3.77Å; P324-F352 HydrophobicContact CG-CZ 4.44Å; M329-F352 HydrophobicContact CE-CE1 4.04Å; M329-F352 HydrophobicContact CE-CZ 3.84Å; V341-F352 HydrophobicContact CG1-CE2 4.12Å; V341-F352 HydrophobicContact CG1-CZ 4.3Å; D348-F352 WeakPolarHBondContact O-CB 3.37Å; D348-F352 PolarHBondContact O-N 3.35Å; A349-F352 WeakPolarHBondContact O-CB 3.46Å; A349-F352 PolarHBondContact O-N 2.89Å; I350-F352 VanDerWaalsContact C-N 3.32Å; I350-F352 PolarHBondContact O-N 2.66Å; F352-G355 PolarHBondContact O-N 3.44Å; F352-K356 HydrophobicContact CE1-CD 4.02Å; F352-K356 VanDerWaalsContact CZ-CE 3.47Å
353I98.7Very high98.3Very high8 Ų841.1 Ų41.14%0.04123%0.225CC..Hα-helixtrans-63-48178.9-67.9163.8000110.2P214 L249 A349 I350 G355 K356 L362 M375 T379P214-I353 HydrophobicContact CB-CD1 4.02Å; P214-I353 HydrophobicContact CB-CG1 3.91Å; P214-I353 HydrophobicContact CG-CD1 4.03Å; P214-I353 HydrophobicContact CG-CG1 3.98Å; P214-I353 HydrophobicContact CG-CG2 4.3Å; L249-I353 HydrophobicContact CD1-CD1 4.05Å; L249-I353 HydrophobicContact CD1-CG1 3.85Å; A349-I353 VanDerWaalsContact O-CG1 3.27Å; A349-I353 WeakPolarHBondContact O-CG1 3.43Å; A349-I353 PolarHBondContact O-N 2.86Å; I350-I353 PolarHBondContact O-N 3.08Å; I353-G355 PolarHBondContact O-N 2.82Å; I353-K356 PolarHBondContact O-N 3.35Å; I353-K356 VanDerWaalsContact O-N 3.1Å; I353-L362 HydrophobicContact CD1-CD1 4.02Å; I353-M375 HydrophobicContact CD1-SD 3.83Å; I353-T379 HydrophobicContact CB-CG2 4.44Å; I353-T379 HydrophobicContact CG2-CG2 4.1Å
354N98.7Very high98.4Very high88 Ų8840.5 Ų40.547%0.47122%0.221SC..Hα-helixtrans-69.6-17.5-179-71.8-18.8000113.7I350 R351 K356 E378I350-N354 WeakPolarHBondContact O-CB 3.27Å; I350-N354 PolarHBondContact O-N 2.91Å; I350-N354 PolarHBondContact O-ND2 3.39Å; R351-N354 PolarHBondContact O-N 3.17Å; N354-K356 PolarHBondContact O-N 3.05Å; N354-E378 PolarHBondContact ND2-O 3.5Å
355G97.9Very high98.5Very high67 Ų6738.5 Ų38.569%0.69120%0.199SC*.THydrogen-bonded Turntrans-75.90.1171.600000114.3R351 F352 I353R351-G355 PolarHBondContact O-N 2.94Å; F352-G355 PolarHBondContact O-N 3.44Å; I353-G355 PolarHBondContact O-N 2.82Å
356K97.2Very high98.6Very high57 Ų5735 Ų3525%0.24818%0.18CC..SBendtrans-123.9170.6-178.9-66.8178.8178-72.80111M329 F352 I353 N354M329-K356 PolarHBondContact O-NZ 2.9Å; F352-K356 HydrophobicContact CE1-CD 4.02Å; F352-K356 VanDerWaalsContact CZ-CE 3.47Å; I353-K356 PolarHBondContact O-N 3.35Å; I353-K356 VanDerWaalsContact O-N 3.1Å; N354-K356 PolarHBondContact O-N 3.05Å
357E98.3Very high98.5Very high127 Ų12738.3 Ų38.359%0.59321%0.205SC*.PPolyproline II helixtrans-62.6147172.3-68.9-68.1176.700111.7P359 Q405E357-P359 WeakPolarHBondContact O-CD 3.44Å; E357-Q405 HydrophobicContact CB-CB 4.16Å; E357-Q405 HydrophobicContact CB-CG 4.12Å; E357-Q405 HydrophobicContact CG-CB 4.37Å; E357-Q405 HydrophobicContact CG-CG 3.79Å; E357-Q405 WeakPolarHBondContact OE2-CG 3.22Å
358K98.8Very high98.5Very high89 Ų8941 Ų4139%0.38722%0.217SC..PPolyproline II helixtrans-64.9121.5-176.9-65.9-179.1179.7-163.50111.3S380 V403 S406K358-S380 WeakPolarHBondContact CD-OG 3.5Å; K358-S380 WeakPolarHBondContact CE-OG 3.1Å; K358-S380 PolarHBondContact NZ-OG 3.45Å; K358-V403 HydrophobicContact CB-CG1 4.13Å; K358-V403 WeakPolarHBondContact CB-O 3.26Å; K358-V403 HydrophobicContact CD-CG1 3.99Å; K358-V403 HydrophobicContact CD-CG2 4.13Å; K358-S406 VanDerWaalsContact O-CB 3.29Å; K358-S406 WeakPolarHBondContact O-CB 3.22Å; K358-S406 PolarHBondContact O-OG 3.31Å; K358-S406 VanDerWaalsContact O-OG 3.05Å
359P98.8Very high98.4Very high5 Ų545.9 Ų45.93%0.03224%0.236CC..PPolyproline II helixtrans-81.6163.2-175.934.1-36.5000112.3K212 P214 E357 S381 G382 S406K212-P359 WeakPolarHBondContact O-CB 3.4Å; P214-P359 HydrophobicContact CG-CG 4.24Å; E357-P359 WeakPolarHBondContact O-CD 3.44Å; P359-S381 VanDerWaalsContact O-CA 3.28Å; P359-S381 WeakPolarHBondContact O-CA 3.31Å; P359-S381 WeakPolarHBondContact O-CB 3.41Å; P359-G382 PolarHBondContact O-N 2.88Å; P359-S406 PolarHBondContact O-OG 2.8Å
360L98.8Very high98.4Very high3 Ų353.3 Ų53.32%0.01627%0.268CS..SBendtrans-68-40.1174.3-175.759.6000111.5C242 I243 G382 G383 F400C242-L360 HydrophobicContact CB-CD2 3.68Å; I243-L360 HydrophobicContact CG2-CB 4.42Å; I243-L360 HydrophobicContact CG2-CD2 3.49Å; I243-L360 VanDerWaalsContact CG2-CD2 3.49Å; I243-L360 HydrophobicContact CG2-CG 3.73Å; L360-G382 CarbonylContact O-C 3.47Å; L360-G382 WeakPolarHBondContact O-CA 3.1Å; L360-G382 PolarHBondContact O-N 2.85Å; L360-G382 VanDerWaalsContact O-N 3.17Å; L360-G383 PolarHBondContact O-N 3.06Å; L360-F400 HydrophobicContact CD2-CE2 4.44Å; L360-F400 HydrophobicContact CD2-CZ 3.91Å; L360-F400 HydrophobicContact CG-CZ 4.44Å
361A98.9Very high98.4Very high0 Ų053.7 Ų53.70%027%0.27CS..EExtended strand (participates in β ladder)trans-129.5153.717700000112.2S213 P214 I243 Y363 G383S213-A361 VanDerWaalsContact CA-O 3.28Å; S213-A361 WeakPolarHBondContact CA-O 3.11Å; S213-A361 VanDerWaalsContact CB-O 3.24Å; S213-A361 WeakPolarHBondContact CB-O 3.2Å; S213-A361 PolarHBondContact OG-N 3.05Å; S213-A361 PolarHBondContact OG-O 3.16Å; P214-A361 WeakPolarHBondContact CD-O 3.09Å; I243-A361 HydrophobicContact CB-CB 4.17Å; I243-A361 HydrophobicContact CG2-CB 4.02Å; A361-Y363 HydrophobicContact CB-CE1 4.22Å; A361-Y363 HydrophobicContact CB-CE2 4.03Å; A361-G383 WeakPolarHBondContact CA-O 3.44Å
362L98.9Very high98.4Very high1 Ų147.6 Ų47.61%0.00525%0.25CC..EExtended strand (participates in β ladder)trans-129.2132.5170.4162.466.7000108.7P214 I353 V364 M375 T379 G383 V384 V385P214-L362 HydrophobicContact CB-CD1 4.36Å; P214-L362 HydrophobicContact CG-CB 4.47Å; P214-L362 HydrophobicContact CG-CD1 3.61Å; I353-L362 HydrophobicContact CD1-CD1 4.02Å; L362-V364 HydrophobicContact CD1-CG2 4.28Å; L362-V364 HydrophobicContact CG-CG2 4.18Å; L362-M375 HydrophobicContact CD1-CG 4.29Å; L362-M375 HydrophobicContact CD2-CG 4.09Å; L362-T379 WeakPolarHBondContact CD2-OG1 3.36Å; L362-G383 PolarHBondContact N-O 3.09Å; L362-V384 HydrophobicContact CB-CG2 4.26Å; L362-V384 HydrophobicContact CD2-CG1 4.31Å; L362-V384 HydrophobicContact CD2-CG2 4.07Å; L362-V384 HydrophobicContact CG-CG1 4.26Å; L362-V384 HydrophobicContact CG-CG2 4.49Å; L362-V384 WeakPolarHBondContact O-CA 3.34Å; L362-V385 PolarHBondContact O-N 3.16Å
363Y98.9Very high98.4Very high0 Ų052.9 Ų52.90%027%0.272CS..EExtended strand (participates in β ladder)trans-117134.6179.9-57.1-58000111.4P214 C215 Y216 I243 P245 A361 V385 D388 V389 I390P214-Y363 PolarHBondContact O-N 3.02Å; C215-Y363 WeakPolarHBondContact CA-O 3.42Å; Y216-Y363 PolarHBondContact N-O 2.85Å; I243-Y363 VanDerWaalsContact O-CE2 3.32Å; I243-Y363 WeakPolarHBondContact O-CE2 3.39Å; I243-Y363 VanDerWaalsContact O-CZ 3.31Å; I243-Y363 PolarHBondContact O-OH 3.21Å; P245-Y363 HydrophobicContact CB-CD2 4.02Å; P245-Y363 HydrophobicContact CB-CE2 4.29Å; A361-Y363 HydrophobicContact CB-CE1 4.22Å; A361-Y363 HydrophobicContact CB-CE2 4.03Å; Y363-V385 WeakPolarHBondContact CA-O 3.35Å; Y363-V385 HydrophobicContact CD1-CB 3.8Å; Y363-V385 HydrophobicContact CD1-CG2 4.21Å; Y363-V385 HydrophobicContact CE1-CB 3.9Å; Y363-V385 HydrophobicContact CE1-CG2 3.8Å; Y363-D388 WeakPolarHBondContact CD1-O 3.46Å; Y363-V389 HydrophobicContact CD1-CB 4.16Å; Y363-V389 HydrophobicContact CD1-CG1 3.94Å; Y363-V389 HydrophobicContact CD2-CG1 4.02Å; Y363-V389 HydrophobicContact CE1-CB 4Å; Y363-V389 HydrophobicContact CE1-CG1 4.26Å; Y363-V389 HydrophobicContact CE2-CB 4.33Å; Y363-V389 HydrophobicContact CE2-CG1 4.3Å; Y363-V389 HydrophobicContact CG-CB 4.42Å; Y363-V389 HydrophobicContact CG-CG1 3.8Å; Y363-I390 PolarHBondContact OH-N 2.76Å; Y363-I390 VanDerWaalsContact OH-N 3.11Å
364V98.8Very high98.3Very high0 Ų057.3 Ų57.30%029%0.288CS..EExtended strand (participates in β ladder)trans-134114.5-177.6-169.90000109.7Y216 L362 I372 M375 V385 V386 N387Y216-V364 HydrophobicContact CD1-CG1 4.28Å; L362-V364 HydrophobicContact CD1-CG2 4.28Å; L362-V364 HydrophobicContact CG-CG2 4.18Å; V364-I372 HydrophobicContact CG1-CG1 4.41Å; V364-M375 HydrophobicContact CG1-CB 4.44Å; V364-M375 HydrophobicContact CG2-CB 4.08Å; V364-M375 HydrophobicContact CG2-CG 3.57Å; V364-V385 PolarHBondContact N-O 2.78Å; V364-V386 HydrophobicContact CB-CG2 4.5Å; V364-V386 CarbonylContact O-C 3.57Å; V364-V386 VanDerWaalsContact O-CA 3.3Å; V364-V386 WeakPolarHBondContact O-CA 3.26Å; V364-N387 PolarHBondContact O-N 2.81Å
365F98.9Very high98.4Very high4 Ų453.1 Ų53.12%0.01827%0.266CS..EExtended strand (participates in β ladder)trans-104109.4173.2-71.6-96.4000109.1C215 Y216 I217 D218 A226 R229 I230 N387 V389C215-F365 VanDerWaalsContact SG-CE2 3.57Å; Y216-F365 PolarHBondContact O-N 2.68Å; I217-F365 HydrophobicContact CG1-CB 4.49Å; I217-F365 HydrophobicContact CG2-CB 4.42Å; D218-F365 VanDerWaalsContact CB-O 3.24Å; D218-F365 WeakPolarHBondContact CB-O 3.45Å; D218-F365 PolarHBondContact N-O 2.66Å; A226-F365 HydrophobicContact CB-CB 4.19Å; A226-F365 HydrophobicContact CB-CD1 3.43Å; A226-F365 VanDerWaalsContact CB-CD1 3.43Å; A226-F365 HydrophobicContact CB-CE1 4Å; A226-F365 HydrophobicContact CB-CG 3.92Å; R229-F365 HydrophobicContact CB-CE1 4.16Å; R229-F365 HydrophobicContact CB-CZ 4.16Å; I230-F365 HydrophobicContact CD1-CD2 3.9Å; I230-F365 HydrophobicContact CD1-CE2 3.72Å; I230-F365 HydrophobicContact CD1-CG 4.49Å; I230-F365 HydrophobicContact CD1-CZ 4.15Å; I230-F365 HydrophobicContact CG1-CD2 4.23Å; I230-F365 HydrophobicContact CG1-CE1 4.49Å; I230-F365 HydrophobicContact CG1-CE2 3.51Å; I230-F365 HydrophobicContact CG1-CZ 3.67Å; F365-N387 VanDerWaalsContact CA-OD1 3.32Å; F365-N387 WeakPolarHBondContact CA-OD1 3.33Å; F365-N387 WeakPolarHBondContact CE1-O 3.43Å; F365-V389 HydrophobicContact CE2-CG1 3.97Å; F365-V389 HydrophobicContact CZ-CG1 3.99Å
366S98.4Very high98.4Very high0 Ų053.9 Ų53.90%025%0.254CS..  trans-163.5148.7-179.9178.80000110.8D218 D368 N387D218-S366 WeakPolarHBondContact OD2-CB 3.18Å; D218-S366 PolarHBondContact OD2-OG 3.12Å; S366-D368 PolarHBondContact OG-N 2.87Å; S366-N387 PolarHBondContact N-OD1 2.76Å; S366-N387 PolarHBondContact O-ND2 2.93Å; S366-N387 PolarHBondContact O-OD1 2.67Å
367S97.1Very high98.5Very high88 Ų8855.2 Ų55.262%0.61528%0.275SS*.SBendtrans-92.4-14.2166.5-46.20000112.4D220 K369D220-S367 VanDerWaalsContact O-CB 3.24Å; D220-S367 WeakPolarHBondContact O-CB 3.2Å; D220-S367 PolarHBondContact O-N 2.67Å; D220-S367 VanDerWaalsContact O-N 3.13Å; D220-S367 PolarHBondContact O-OG 2.67Å; S367-K369 PolarHBondContact O-N 3.25Å
368D97.8Very high98.5Very high62 Ų6253 Ų5333%0.33227%0.265SS..  trans-82.9111.9179-173.7-0.5000111.5S366 K370 V371 I372S366-D368 PolarHBondContact OG-N 2.87Å; D368-K370 PolarHBondContact O-N 3.47Å; D368-K370 VanDerWaalsContact O-N 3.17Å; D368-K370 WeakPolarHBondContact OD1-CB 3.29Å; D368-K370 PolarHBondContact OD1-N 2.87Å; D368-V371 HydrophobicContact CB-CB 4.14Å; D368-V371 HydrophobicContact CB-CG2 3.93Å; D368-V371 WeakPolarHBondContact O-CB 3.48Å; D368-V371 PolarHBondContact O-N 2.98Å; D368-V371 VanDerWaalsContact O-N 3.17Å; D368-I372 WeakPolarHBondContact O-CG1 3.45Å; D368-I372 PolarHBondContact O-N 3.44Å; D368-I372 VanDerWaalsContact O-N 3.09Å
369K97.5Very high98.5Very high161 Ų16149.8 Ų49.870%0.725%0.252SS*.Hα-helixtrans-59.4-26.7176.2-64.4-179.1-178.5176.20112.9S367 K373S367-K369 PolarHBondContact O-N 3.25Å; K369-K373 WeakPolarHBondContact O-CB 3.48Å; K369-K373 VanDerWaalsContact O-CG 3.22Å; K369-K373 WeakPolarHBondContact O-CG 3.44Å; K369-K373 PolarHBondContact O-N 3.03Å
370K98Very high98.5Very high156 Ų15651.6 Ų51.668%0.67827%0.265SS*.Hα-helixtrans-71.3-46.3176.7-64.1177.2-178.9173.60110.6D368 I372 K373 R374D368-K370 PolarHBondContact O-N 3.47Å; D368-K370 VanDerWaalsContact O-N 3.17Å; D368-K370 WeakPolarHBondContact OD1-CB 3.29Å; D368-K370 PolarHBondContact OD1-N 2.87Å; K370-I372 VanDerWaalsContact C-N 3.35Å; K370-I372 PolarHBondContact O-N 3.44Å; K370-K373 PolarHBondContact O-N 3.18Å; K370-R374 WeakPolarHBondContact O-CB 3.49Å; K370-R374 VanDerWaalsContact O-CG 3.27Å; K370-R374 WeakPolarHBondContact O-CG 3.23Å; K370-R374 PolarHBondContact O-N 3.45Å
371V98.3Very high98.5Very high14 Ų1452.4 Ų52.49%0.08527%0.271CS..Hα-helixtrans-56-50.6174168.40000110.2Y216 V346 D368 K373 R374 M375Y216-V371 HydrophobicContact CD1-CG1 4.41Å; Y216-V371 HydrophobicContact CE1-CG1 3.8Å; V346-V371 HydrophobicContact CB-CG1 4.47Å; V346-V371 HydrophobicContact CG2-CG1 3.89Å; D368-V371 HydrophobicContact CB-CB 4.14Å; D368-V371 HydrophobicContact CB-CG2 3.93Å; D368-V371 WeakPolarHBondContact O-CB 3.48Å; D368-V371 PolarHBondContact O-N 2.98Å; D368-V371 VanDerWaalsContact O-N 3.17Å; V371-K373 PolarHBondContact O-N 3.37Å; V371-R374 PolarHBondContact O-N 3.47Å; V371-M375 WeakPolarHBondContact O-CB 3.38Å; V371-M375 PolarHBondContact O-N 2.93Å
372I98.5Very high98.5Very high29 Ų2953.9 Ų53.915%0.14929%0.287CS..Hα-helixtrans-58.1-51.4179.2-65160.2000111.5V364 D368 K370 R374 M375 I376 V386V364-I372 HydrophobicContact CG1-CG1 4.41Å; D368-I372 WeakPolarHBondContact O-CG1 3.45Å; D368-I372 PolarHBondContact O-N 3.44Å; D368-I372 VanDerWaalsContact O-N 3.09Å; K370-I372 VanDerWaalsContact C-N 3.35Å; K370-I372 PolarHBondContact O-N 3.44Å; I372-R374 VanDerWaalsContact C-N 3.33Å; I372-R374 PolarHBondContact O-N 2.99Å; I372-M375 PolarHBondContact O-N 3.01Å; I372-I376 HydrophobicContact CG2-CD1 3.87Å; I372-I376 WeakPolarHBondContact O-CG1 3.5Å; I372-I376 PolarHBondContact O-N 3.35Å; I372-I376 VanDerWaalsContact O-N 3.09Å; I372-V386 HydrophobicContact CD1-CG1 3.63Å; I372-V386 HydrophobicContact CG1-CG1 3.78Å; I372-V386 HydrophobicContact CG2-CB 4.48Å; I372-V386 HydrophobicContact CG2-CG1 4.04Å; I372-V386 HydrophobicContact CG2-CG2 3.64Å
373K98.5Very high98.5Very high151 Ų15154.6 Ų54.666%0.65729%0.294SS*.Hα-helixtrans-61.7-41.6-178.9-78.4178.1179.3-173.60112.1K369 K370 V371 A377K369-K373 WeakPolarHBondContact O-CB 3.48Å; K369-K373 VanDerWaalsContact O-CG 3.22Å; K369-K373 WeakPolarHBondContact O-CG 3.44Å; K369-K373 PolarHBondContact O-N 3.03Å; K370-K373 PolarHBondContact O-N 3.18Å; V371-K373 PolarHBondContact O-N 3.37Å; K373-A377 WeakPolarHBondContact O-CB 3.42Å; K373-A377 PolarHBondContact O-N 2.99Å
374R98.5Very high98.5Very high101 Ų10157 Ų5738%0.38131%0.309SS..Hα-helixtrans-64.6-47.2178-74.9-172.766.7-150.9-8.8111.5I350 K370 V371 I372 I376 A377 E378I350-R374 HydrophobicContact CD1-CB 4.35Å; K370-R374 WeakPolarHBondContact O-CB 3.49Å; K370-R374 VanDerWaalsContact O-CG 3.27Å; K370-R374 WeakPolarHBondContact O-CG 3.23Å; K370-R374 PolarHBondContact O-N 3.45Å; V371-R374 PolarHBondContact O-N 3.47Å; I372-R374 VanDerWaalsContact C-N 3.33Å; I372-R374 PolarHBondContact O-N 2.99Å; R374-I376 VanDerWaalsContact C-N 3.3Å; R374-I376 PolarHBondContact O-N 3.32Å; R374-A377 PolarHBondContact O-N 3.43Å; R374-E378 WeakPolarHBondContact CB-OE1 3.37Å; R374-E378 WeakPolarHBondContact CG-OE1 3.48Å; R374-E378 IonicContact CZ-OE1 3.69Å; R374-E378 IonicContact NE-OE1 3.82Å; R374-E378 PolarHBondContact NE-OE1 2.99Å; R374-E378 IonicContact NE-OE2 2.78Å; R374-E378 IonicContact NH2-OE1 2.7Å; R374-E378 PolarHBondContact NH2-OE1 3.42Å; R374-E378 IonicContact NH2-OE2 2.67Å; R374-E378 PolarHBondContact NH2-OE2 3.03Å; R374-E378 VanDerWaalsContact O-CB 3.26Å; R374-E378 WeakPolarHBondContact O-CB 3.32Å; R374-E378 WeakPolarHBondContact O-CG 3.36Å; R374-E378 PolarHBondContact O-N 3.28Å
375M98.8Very high98.5Very high0 Ų057.8 Ų57.80%031%0.313CS..Hα-helixtrans-58.3-43.6178.7-165.867.876.900111.6Y216 V346 A349 I350 I353 L362 V364 V371 I372 T379Y216-M375 HydrophobicContact CD1-CE 3.61Å; Y216-M375 HydrophobicContact CD2-CE 4.16Å; Y216-M375 HydrophobicContact CE1-CE 4.22Å; Y216-M375 HydrophobicContact CG-CE 3.56Å; V346-M375 HydrophobicContact CG2-CE 3.85Å; A349-M375 HydrophobicContact CB-CE 4.08Å; I350-M375 HydrophobicContact CD1-SD 4.43Å; I350-M375 HydrophobicContact CG1-CE 4.2Å; I350-M375 HydrophobicContact CG1-SD 3.55Å; I350-M375 VanDerWaalsContact CG1-SD 3.55Å; I353-M375 HydrophobicContact CD1-SD 3.83Å; L362-M375 HydrophobicContact CD1-CG 4.29Å; L362-M375 HydrophobicContact CD2-CG 4.09Å; V364-M375 HydrophobicContact CG1-CB 4.44Å; V364-M375 HydrophobicContact CG2-CB 4.08Å; V364-M375 HydrophobicContact CG2-CG 3.57Å; V371-M375 WeakPolarHBondContact O-CB 3.38Å; V371-M375 PolarHBondContact O-N 2.93Å; I372-M375 PolarHBondContact O-N 3.01Å; M375-T379 WeakPolarHBondContact O-CB 3.4Å; M375-T379 WeakPolarHBondContact O-CG2 3.36Å; M375-T379 PolarHBondContact O-N 3.33Å; M375-T379 PolarHBondContact O-OG1 2.96Å; M375-T379 HydrophobicContact SD-CG2 4.04Å
376I98.8Very high98.5Very high84 Ų8460 Ų6043%0.43133%0.327SS..Hα-helixtrans-67.3-43.2177.1-66.3168.3000111.8I372 R374 V384 V386I372-I376 HydrophobicContact CG2-CD1 3.87Å; I372-I376 WeakPolarHBondContact O-CG1 3.5Å; I372-I376 PolarHBondContact O-N 3.35Å; I372-I376 VanDerWaalsContact O-N 3.09Å; R374-I376 VanDerWaalsContact C-N 3.3Å; R374-I376 PolarHBondContact O-N 3.32Å; I376-V384 HydrophobicContact CD1-CG1 4.5Å; I376-V384 HydrophobicContact CG1-CG1 4.05Å; I376-V386 HydrophobicContact CD1-CG2 4.33Å
377A98.8Very high98.5Very high84 Ų8462.6 Ų62.669%0.69434%0.341SS*.Hα-helixtrans-76.6-28.9-174.200000113.7K373 R374K373-A377 WeakPolarHBondContact O-CB 3.42Å; K373-A377 PolarHBondContact O-N 2.99Å; R374-A377 PolarHBondContact O-N 3.43Å
378E98.9Very high98.6Very high81 Ų8160.2 Ų60.238%0.37932%0.321SS..Hα-helixtrans-103.21.5-172.1-60.9173.7-141.500112.9I350 N354 R374I350-E378 HydrophobicContact CD1-CB 4.15Å; I350-E378 HydrophobicContact CG2-CB 3.8Å; N354-E378 PolarHBondContact ND2-O 3.5Å; R374-E378 WeakPolarHBondContact CB-OE1 3.37Å; R374-E378 WeakPolarHBondContact CG-OE1 3.48Å; R374-E378 IonicContact CZ-OE1 3.69Å; R374-E378 IonicContact NE-OE1 3.82Å; R374-E378 PolarHBondContact NE-OE1 2.99Å; R374-E378 IonicContact NE-OE2 2.78Å; R374-E378 IonicContact NH2-OE1 2.7Å; R374-E378 PolarHBondContact NH2-OE1 3.42Å; R374-E378 IonicContact NH2-OE2 2.67Å; R374-E378 PolarHBondContact NH2-OE2 3.03Å; R374-E378 VanDerWaalsContact O-CB 3.26Å; R374-E378 WeakPolarHBondContact O-CB 3.32Å; R374-E378 WeakPolarHBondContact O-CG 3.36Å; R374-E378 PolarHBondContact O-N 3.28Å
379T98.9Very high98.6Very high21 Ų2157.2 Ų57.213%0.12931%0.305CS..  trans-127.8175.5176.970.10000112.2I350 I353 L362 M375I350-T379 HydrophobicContact CB-CG2 4.49Å; I350-T379 HydrophobicContact CG1-CG2 4.22Å; I350-T379 HydrophobicContact CG2-CG2 4.17Å; I353-T379 HydrophobicContact CB-CG2 4.44Å; I353-T379 HydrophobicContact CG2-CG2 4.1Å; L362-T379 WeakPolarHBondContact CD2-OG1 3.36Å; M375-T379 WeakPolarHBondContact O-CB 3.4Å; M375-T379 WeakPolarHBondContact O-CG2 3.36Å; M375-T379 PolarHBondContact O-N 3.33Å; M375-T379 PolarHBondContact O-OG1 2.96Å; M375-T379 HydrophobicContact SD-CG2 4.04Å
380S98.8Very high98.6Very high43 Ų4350.2 Ų50.230%0.30128%0.275SS..  trans-142.6124.6177.8-175.80000110.8K358K358-S380 WeakPolarHBondContact CD-OG 3.5Å; K358-S380 WeakPolarHBondContact CE-OG 3.1Å; K358-S380 PolarHBondContact NZ-OG 3.45Å
381S98.9Very high98.6Very high21 Ų2146.6 Ų46.615%0.14726%0.262CS..  trans-143.1171.1176.460.90000110.4P359 G383 V384 V403P359-S381 VanDerWaalsContact O-CA 3.28Å; P359-S381 WeakPolarHBondContact O-CA 3.31Å; P359-S381 WeakPolarHBondContact O-CB 3.41Å; S381-G383 PolarHBondContact OG-O 3.32Å; S381-V384 WeakPolarHBondContact OG-CG2 3.28Å; S381-V403 VanDerWaalsContact C-CG1 3.49Å
382G98.7Very high98.6Very high31 Ų3147.1 Ų47.132%0.3226%0.263SS..SBendtrans-64.3-51.5172.500000112.3P359 L360 G401P359-G382 PolarHBondContact O-N 2.88Å; L360-G382 CarbonylContact O-C 3.47Å; L360-G382 WeakPolarHBondContact O-CA 3.1Å; L360-G382 PolarHBondContact O-N 2.85Å; L360-G382 VanDerWaalsContact O-N 3.17Å; G382-G401 CarbonylContact C-O 3.56Å; G382-G401 WeakPolarHBondContact CA-O 3.41Å
383G98.6Very high98.4Very high15 Ų1547.9 Ų47.916%0.15527%0.265CS..EExtended strand (participates in β ladder)trans-134.8164.317400000113L360 A361 L362 S381L360-G383 PolarHBondContact O-N 3.06Å; A361-G383 WeakPolarHBondContact CA-O 3.44Å; L362-G383 PolarHBondContact N-O 3.09Å; S381-G383 PolarHBondContact OG-O 3.32Å
384V98.8Very high98.2Very high52 Ų5245 Ų4532%0.31526%0.259SS..EExtended strand (participates in β ladder)trans-131.6136.8175-174.20000109.7L362 I376 S381 V386L362-V384 HydrophobicContact CB-CG2 4.26Å; L362-V384 HydrophobicContact CD2-CG1 4.31Å; L362-V384 HydrophobicContact CD2-CG2 4.07Å; L362-V384 HydrophobicContact CG-CG1 4.26Å; L362-V384 HydrophobicContact CG-CG2 4.49Å; L362-V384 WeakPolarHBondContact O-CA 3.34Å; I376-V384 HydrophobicContact CD1-CG1 4.5Å; I376-V384 HydrophobicContact CG1-CG1 4.05Å; S381-V384 WeakPolarHBondContact OG-CG2 3.28Å; V384-V386 HydrophobicContact CG1-CG2 4.47Å
385V98.9Very high97.9Very high16 Ų1644.4 Ų44.410%0.09726%0.263CS..EExtended strand (participates in β ladder)trans-124.5133.1167.5-169.20000109.5L362 Y363 V364 D388 H392L362-V385 PolarHBondContact O-N 3.16Å; Y363-V385 WeakPolarHBondContact CA-O 3.35Å; Y363-V385 HydrophobicContact CD1-CB 3.8Å; Y363-V385 HydrophobicContact CD1-CG2 4.21Å; Y363-V385 HydrophobicContact CE1-CB 3.9Å; Y363-V385 HydrophobicContact CE1-CG2 3.8Å; V364-V385 PolarHBondContact N-O 2.78Å; V385-D388 WeakPolarHBondContact CB-O 3.34Å; V385-D388 HydrophobicContact CG1-CB 3.79Å; V385-D388 VanDerWaalsContact CG1-O 3.23Å; V385-D388 WeakPolarHBondContact CG1-O 3.45Å; V385-H392 HydrophobicContact CG2-CB 3.72Å; V385-H392 WeakPolarHBondContact CG2-ND1 3.49Å
386V98.7Very high97.5Very high51 Ų5145.8 Ų45.831%0.30927%0.271SS..EExtended strand (participates in β ladder)trans-106.2129.4177179.70000108.5V364 I372 I376 V384 D388V364-V386 HydrophobicContact CB-CG2 4.5Å; V364-V386 CarbonylContact O-C 3.57Å; V364-V386 VanDerWaalsContact O-CA 3.3Å; V364-V386 WeakPolarHBondContact O-CA 3.26Å; I372-V386 HydrophobicContact CD1-CG1 3.63Å; I372-V386 HydrophobicContact CG1-CG1 3.78Å; I372-V386 HydrophobicContact CG2-CB 4.48Å; I372-V386 HydrophobicContact CG2-CG1 4.04Å; I372-V386 HydrophobicContact CG2-CG2 3.64Å; I376-V386 HydrophobicContact CD1-CG2 4.33Å; V384-V386 HydrophobicContact CG1-CG2 4.47Å; V386-D388 PolarHBondContact O-N 2.95Å
387N98.6Very high97.2Very high54 Ų5445.8 Ų45.829%0.28928%0.278SS..SBendtrans6115.8-179.7-63.1-37.6000114.9R229 V364 F365 S366R229-N387 WeakPolarHBondContact CD-O 3.37Å; R229-N387 PolarHBondContact NH1-O 2.76Å; V364-N387 PolarHBondContact O-N 2.81Å; F365-N387 VanDerWaalsContact CA-OD1 3.32Å; F365-N387 WeakPolarHBondContact CA-OD1 3.33Å; F365-N387 WeakPolarHBondContact CE1-O 3.43Å; S366-N387 PolarHBondContact N-OD1 2.76Å; S366-N387 PolarHBondContact O-ND2 2.93Å; S366-N387 PolarHBondContact O-OD1 2.67Å
388D98.8Very high97.1Very high37 Ų3745.3 Ų45.320%0.19826%0.264CS..SBendtrans-154176.7170.7-142.6-30.1000110.4R229 Y363 V385 V386 M391R229-D388 WeakPolarHBondContact CD-OD1 3.25Å; R229-D388 IonicContact CZ-OD2 3.6Å; R229-D388 IonicContact NE-OD1 3.97Å; R229-D388 IonicContact NE-OD2 2.64Å; R229-D388 PolarHBondContact NE-OD2 2.64Å; Y363-D388 WeakPolarHBondContact CD1-O 3.46Å; V385-D388 WeakPolarHBondContact CB-O 3.34Å; V385-D388 HydrophobicContact CG1-CB 3.79Å; V385-D388 VanDerWaalsContact CG1-O 3.23Å; V385-D388 WeakPolarHBondContact CG1-O 3.45Å; V386-D388 PolarHBondContact O-N 2.95Å; D388-M391 HydrophobicContact CB-CG 4.43Å
389V98.8Very high97.1Very high0 Ų044.3 Ų44.30%026%0.264CS..SBendtrans-127.4156.1175.5-61.40000110.4R229 I230 W232 P245 Y363 F365 M391R229-V389 VanDerWaalsContact O-CG2 3.23Å; R229-V389 WeakPolarHBondContact O-CG2 3.39Å; I230-V389 HydrophobicContact CG1-CG1 4.34Å; W232-V389 HydrophobicContact CE3-CG2 3.84Å; W232-V389 HydrophobicContact CZ3-CG2 3.93Å; P245-V389 HydrophobicContact CG-CG1 4.36Å; Y363-V389 HydrophobicContact CD1-CB 4.16Å; Y363-V389 HydrophobicContact CD1-CG1 3.94Å; Y363-V389 HydrophobicContact CD2-CG1 4.02Å; Y363-V389 HydrophobicContact CE1-CB 4Å; Y363-V389 HydrophobicContact CE1-CG1 4.26Å; Y363-V389 HydrophobicContact CE2-CB 4.33Å; Y363-V389 HydrophobicContact CE2-CG1 4.3Å; Y363-V389 HydrophobicContact CG-CB 4.42Å; Y363-V389 HydrophobicContact CG-CG1 3.8Å; F365-V389 HydrophobicContact CE2-CG1 3.97Å; F365-V389 HydrophobicContact CZ-CG1 3.99Å; V389-M391 WeakPolarHBondContact O-CG 2.93Å; V389-M391 PolarHBondContact O-N 3.43Å
390I98Very high97.1Very high14 Ų1444.1 Ų44.17%0.07226%0.261CS..SBendtrans65.7-34.9173.9-58.4179.4000115.6W232 I243 Y363 H392 Y393W232-I390 HydrophobicContact CH2-CB 3.96Å; W232-I390 HydrophobicContact CH2-CD1 4.17Å; W232-I390 HydrophobicContact CH2-CG2 4.11Å; W232-I390 HydrophobicContact CZ3-CB 3.94Å; W232-I390 HydrophobicContact CZ3-CD1 4.11Å; W232-I390 HydrophobicContact CZ3-CG1 4.34Å; I243-I390 HydrophobicContact CD1-CB 4.38Å; I243-I390 HydrophobicContact CD1-CG1 4.45Å; I243-I390 HydrophobicContact CD1-CG2 3.93Å; I243-I390 HydrophobicContact CG1-CG1 4.34Å; Y363-I390 PolarHBondContact OH-N 2.76Å; Y363-I390 VanDerWaalsContact OH-N 3.11Å; I390-H392 PolarHBondContact O-N 2.95Å; I390-H392 PolarHBondContact O-ND1 3.31Å; I390-Y393 VanDerWaalsContact O-CB 3.25Å; I390-Y393 WeakPolarHBondContact O-CB 3.32Å; I390-Y393 PolarHBondContact O-N 3.05Å
391M97.3Very high97Very high80 Ų8042.5 Ų42.539%0.39425%0.251SS..G310 helixtrans-58.6-20.3-165.8-66.9-49.2-57.900116.3W232 D388 V389 Y393 V394W232-M391 HydrophobicContact CH2-SD 4.16Å; W232-M391 HydrophobicContact CZ3-SD 4.49Å; D388-M391 HydrophobicContact CB-CG 4.43Å; V389-M391 WeakPolarHBondContact O-CG 2.93Å; V389-M391 PolarHBondContact O-N 3.43Å; M391-Y393 PolarHBondContact O-N 3.36Å; M391-V394 HydrophobicContact CE-CG1 4.41Å; M391-V394 HydrophobicContact CE-CG2 3.54Å; M391-V394 WeakPolarHBondContact O-CG2 3.43Å; M391-V394 PolarHBondContact O-N 3.16Å
392H97.5Very high97Very high24 Ų2442 Ų4211%0.11125%0.25CS..G310 helixtrans-62.8-25.7171.666.2-67000113V385 I390 V394 L398V385-H392 HydrophobicContact CG2-CB 3.72Å; V385-H392 WeakPolarHBondContact CG2-ND1 3.49Å; I390-H392 PolarHBondContact O-N 2.95Å; I390-H392 PolarHBondContact O-ND1 3.31Å; H392-V394 VanDerWaalsContact C-N 3.34Å; H392-V394 PolarHBondContact O-N 2.68Å; H392-L398 HydrophobicContact CB-CD1 4.05Å
393Y96Very high97Very high46 Ų4642.8 Ų42.818%0.1825%0.249CC..G310 helixtrans-66.2-31.6178.1-178.9-92.8000113.2Q121 I243 I390 M391 L395 F400 H412Q121-Y393 PolarHBondContact OE1-OH 2.85Å; I243-Y393 HydrophobicContact CD1-CD2 4.22Å; I243-Y393 HydrophobicContact CD1-CG 4.17Å; I390-Y393 VanDerWaalsContact O-CB 3.25Å; I390-Y393 WeakPolarHBondContact O-CB 3.32Å; I390-Y393 PolarHBondContact O-N 3.05Å; M391-Y393 PolarHBondContact O-N 3.36Å; Y393-L395 PolarHBondContact O-N 3.12Å; Y393-F400 HydrophobicContact CD2-CD1 4.12Å; Y393-F400 AromaticContact CD2-CD2 3.85Å; Y393-F400 HydrophobicContact CD2-CD2 3.85Å; Y393-F400 HydrophobicContact CD2-CE1 4Å; Y393-F400 AromaticContact CD2-CE2 3.71Å; Y393-F400 HydrophobicContact CD2-CE2 3.71Å; Y393-F400 HydrophobicContact CD2-CG 4.05Å; Y393-F400 AromaticContact CD2-CZ 3.77Å; Y393-F400 HydrophobicContact CD2-CZ 3.77Å; Y393-F400 HydrophobicContact CE2-CD1 4.1Å; Y393-F400 AromaticContact CE2-CE1 3.9Å; Y393-F400 HydrophobicContact CE2-CE1 3.9Å; Y393-F400 HydrophobicContact CE2-CE2 4.43Å; Y393-F400 HydrophobicContact CE2-CG 4.44Å; Y393-F400 HydrophobicContact CE2-CZ 4.06Å; Y393-H412 AromaticContact CD2-CE1 3.54Å; Y393-H412 AromaticContact CD2-NE2 3.95Å; Y393-H412 AromaticContact CE2-CE1 3.45Å; Y393-H412 VanDerWaalsContact CE2-CE1 3.45Å; Y393-H412 WeakPolarHBondContact CE2-CE1 3.34Å; Y393-H412 AromaticContact CE2-NE2 3.48Å; Y393-H412 WeakPolarHBondContact CE2-NE2 3.48Å; Y393-H412 AromaticContact CG-CE1 3.99Å; Y393-H412 AromaticContact CZ-CE1 3.81Å; Y393-H412 AromaticContact CZ-NE2 3.93Å; Y393-H412 PolarHBondContact O-CE1 3.42Å; Y393-H412 PolarHBondContact O-ND1 2.99Å
394V92.3Very high97Very high90 Ų9044.5 Ų44.555%0.54527%0.266SS..G310 helixtrans-81.6-3.2-173.7-51.10000113.3M391 H392M391-V394 HydrophobicContact CE-CG1 4.41Å; M391-V394 HydrophobicContact CE-CG2 3.54Å; M391-V394 WeakPolarHBondContact O-CG2 3.43Å; M391-V394 PolarHBondContact O-N 3.16Å; H392-V394 VanDerWaalsContact C-N 3.34Å; H392-V394 PolarHBondContact O-N 2.68Å
395L93.1Very high97Very high88 Ų8845 Ų4546%0.46127%0.265SS..  trans-102.595.8-174.2-174.560.3000110.8Y393 S397 L398Y393-L395 PolarHBondContact O-N 3.12Å; L395-S397 WeakPolarHBondContact CG-OG 3.43Å; L395-S397 PolarHBondContact O-N 2.7Å; L395-L398 HydrophobicContact CB-CD1 4.21Å; L395-L398 HydrophobicContact CB-CG 4.35Å; L395-L398 HydrophobicContact CD2-CD1 3.87Å; L395-L398 HydrophobicContact CD2-CG 3.83Å; L395-L398 HydrophobicContact CG-CD1 4.41Å; L395-L398 HydrophobicContact CG-CG 4.19Å; L395-L398 PolarHBondContact O-N 3Å
396N89.9Confident97Very high29 Ų2944.3 Ų44.316%0.15526%0.261CS..THydrogen-bonded Turntrans-59.2-11.1-176.6-57.9-9.9000115.3E68 L71E68-N396 PolarHBondContact OE2-ND2 3Å; L71-N396 HydrophobicContact CD2-CB 3.46Å; L71-N396 VanDerWaalsContact CD2-CB 3.46Å
397S92.6Very high97Very high84 Ų8442 Ų4259%0.58725%0.248SC*.THydrogen-bonded Turntrans-82.9-21.717358.50000113.5L395 H415L395-S397 WeakPolarHBondContact CG-OG 3.43Å; L395-S397 PolarHBondContact O-N 2.7Å; S397-H415 PolarHBondContact O-NE2 3.32Å
398L97.4Very high97Very high75 Ų7543.2 Ų43.239%0.39325%0.252SS..SBendtrans-81.4137.7172.8-68.6177.3000109.6H392 L395 F400H392-L398 HydrophobicContact CB-CD1 4.05Å; L395-L398 HydrophobicContact CB-CD1 4.21Å; L395-L398 HydrophobicContact CB-CG 4.35Å; L395-L398 HydrophobicContact CD2-CD1 3.87Å; L395-L398 HydrophobicContact CD2-CG 3.83Å; L395-L398 HydrophobicContact CG-CD1 4.41Å; L395-L398 HydrophobicContact CG-CG 4.19Å; L395-L398 PolarHBondContact O-N 3Å; L398-F400 PolarHBondContact O-N 3.01Å
399P97.9Very high97Very high60 Ų6042.7 Ų42.739%0.3926%0.256SS..PPolyproline II helixtrans-70130.5165.328.5-29.5000108.8R410 H415P399-R410 HydrophobicContact CB-CB 3.94Å; P399-R410 HydrophobicContact CB-CG 4.05Å; P399-H415 HydrophobicContact CB-CB 4.39Å
400F98.7Very high96.9Very high16 Ų1649.3 Ų49.37%0.0728%0.281CS..BIsolated β-bridgetrans-103.9126.3170.1179.6-101.2000108.8I243 L360 Y393 L398 R410 Y411 H412I243-F400 HydrophobicContact CD1-CE2 4.41Å; I243-F400 HydrophobicContact CG2-CE2 3.87Å; I243-F400 HydrophobicContact CG2-CZ 4.09Å; L360-F400 HydrophobicContact CD2-CE2 4.44Å; L360-F400 HydrophobicContact CD2-CZ 3.91Å; L360-F400 HydrophobicContact CG-CZ 4.44Å; Y393-F400 HydrophobicContact CD2-CD1 4.12Å; Y393-F400 AromaticContact CD2-CD2 3.85Å; Y393-F400 HydrophobicContact CD2-CD2 3.85Å; Y393-F400 HydrophobicContact CD2-CE1 4Å; Y393-F400 AromaticContact CD2-CE2 3.71Å; Y393-F400 HydrophobicContact CD2-CE2 3.71Å; Y393-F400 HydrophobicContact CD2-CG 4.05Å; Y393-F400 AromaticContact CD2-CZ 3.77Å; Y393-F400 HydrophobicContact CD2-CZ 3.77Å; Y393-F400 HydrophobicContact CE2-CD1 4.1Å; Y393-F400 AromaticContact CE2-CE1 3.9Å; Y393-F400 HydrophobicContact CE2-CE1 3.9Å; Y393-F400 HydrophobicContact CE2-CE2 4.43Å; Y393-F400 HydrophobicContact CE2-CG 4.44Å; Y393-F400 HydrophobicContact CE2-CZ 4.06Å; L398-F400 PolarHBondContact O-N 3.01Å; F400-R410 CarbonylContact O-C 3.54Å; F400-R410 VanDerWaalsContact O-CA 3.23Å; F400-R410 WeakPolarHBondContact O-CA 3.22Å; F400-Y411 HydrophobicContact CD1-CD1 4.05Å; F400-Y411 AromaticContact CD1-CE1 3.34Å; F400-Y411 HydrophobicContact CD1-CE1 3.34Å; F400-Y411 AromaticContact CD1-CZ 3.9Å; F400-Y411 AromaticContact CE1-CE1 3.87Å; F400-Y411 HydrophobicContact CE1-CE1 3.87Å; F400-Y411 HydrophobicContact CG-CE1 4.45Å; F400-Y411 PolarHBondContact N-O 2.71Å; F400-Y411 PolarHBondContact O-N 3.45Å; F400-H412 AromaticContact CD1-NE2 3.64Å; F400-H412 AromaticContact CG-NE2 3.81Å
401G98.4Very high97Very high9 Ų948.6 Ų48.69%0.09328%0.277CS..  trans177.3153.7-174.400000112.2E208 G382E208-G401 WeakPolarHBondContact OE1-CA 3.2Å; E208-G401 WeakPolarHBondContact OE2-CA 3.38Å; G382-G401 CarbonylContact C-O 3.56Å; G382-G401 WeakPolarHBondContact CA-O 3.41Å
402G98.6Very high97Very high12 Ų1244.9 Ų44.912%0.12426%0.259CS..  trans-86.6179176.600000114.9G407G402-G407 CarbonylContact C-O 3.58Å
403V98.8Very high97Very high47 Ų4743.9 Ų43.929%0.28526%0.255SS..  trans-144.1130.7172.858.90000110.3K358 S381 S406 G407K358-V403 HydrophobicContact CB-CG1 4.13Å; K358-V403 WeakPolarHBondContact CB-O 3.26Å; K358-V403 HydrophobicContact CD-CG1 3.99Å; K358-V403 HydrophobicContact CD-CG2 4.13Å; S381-V403 VanDerWaalsContact C-CG1 3.49Å; V403-S406 PolarHBondContact N-OG 3.46Å; V403-S406 PolarHBondContact O-OG 3.33Å; V403-G407 CarbonylContact C-O 3.5Å; V403-G407 WeakPolarHBondContact CA-O 3.47Å; V403-G407 PolarHBondContact N-O 2.99Å
404G98.5Very high97.1Very high51 Ų5145 Ų4553%0.52626%0.261SS..BIsolated β-bridgetrans72.1-130.1-176.100000111.1S406 G407G404-S406 PolarHBondContact O-N 3.3Å; G404-G407 PolarHBondContact N-O 2.91Å; G404-G407 PolarHBondContact O-N 3.06Å; G404-G407 VanDerWaalsContact O-N 3.12Å
405Q98.1Very high97.4Very high63 Ų6342.9 Ų42.929%0.29425%0.245SC..THydrogen-bonded Turntrans-65-23.4179.9-72-70.56.500114.1L209 E357 G407L209-Q405 WeakPolarHBondContact CB-O 3.43Å; L209-Q405 VanDerWaalsContact CD1-O 3.31Å; L209-Q405 WeakPolarHBondContact CD1-O 3.49Å; E357-Q405 HydrophobicContact CB-CB 4.16Å; E357-Q405 HydrophobicContact CB-CG 4.12Å; E357-Q405 HydrophobicContact CG-CB 4.37Å; E357-Q405 HydrophobicContact CG-CG 3.79Å; E357-Q405 WeakPolarHBondContact OE2-CG 3.22Å; Q405-G407 VanDerWaalsContact C-N 3.26Å; Q405-G407 PolarHBondContact O-N 3.47Å
406S98.6Very high97.7Very high0 Ų038.7 Ų38.70%022%0.223CC..THydrogen-bonded Turntrans-78.5-8.8175.856.10000113.6L209 G210 K358 P359 V403 G404L209-S406 CarbonylContact C-O 3.51Å; L209-S406 WeakPolarHBondContact CA-O 3.23Å; L209-S406 WeakPolarHBondContact CB-O 3.41Å; L209-S406 PolarHBondContact N-O 3.45Å; G210-S406 VanDerWaalsContact O-CA 3.31Å; G210-S406 WeakPolarHBondContact O-CA 3.3Å; G210-S406 WeakPolarHBondContact O-CB 3.36Å; K358-S406 VanDerWaalsContact O-CB 3.29Å; K358-S406 WeakPolarHBondContact O-CB 3.22Å; K358-S406 PolarHBondContact O-OG 3.31Å; K358-S406 VanDerWaalsContact O-OG 3.05Å; P359-S406 PolarHBondContact O-OG 2.8Å; V403-S406 PolarHBondContact N-OG 3.46Å; V403-S406 PolarHBondContact O-OG 3.33Å; G404-S406 PolarHBondContact O-N 3.3Å
407G98.8Very high98.1Very high3 Ų337.4 Ų37.43%0.03122%0.216CC..EExtended strand (participates in β ladder)trans144.1-178.4172.600000116L207 G402 V403 G404 Q405L207-G407 CarbonylContact O-C 3.45Å; L207-G407 WeakPolarHBondContact O-CA 2.95Å; G402-G407 CarbonylContact C-O 3.58Å; V403-G407 CarbonylContact C-O 3.5Å; V403-G407 WeakPolarHBondContact CA-O 3.47Å; V403-G407 PolarHBondContact N-O 2.99Å; G404-G407 PolarHBondContact N-O 2.91Å; G404-G407 PolarHBondContact O-N 3.06Å; G404-G407 VanDerWaalsContact O-N 3.12Å; Q405-G407 VanDerWaalsContact C-N 3.26Å; Q405-G407 PolarHBondContact O-N 3.47Å
408M98.9Very high98.4Very high79 Ų7935.2 Ų35.239%0.38920%0.198SC..EExtended strand (participates in β ladder)trans-150.4150.1170.267.2175.471.300110.7M195 V205 T206 L207M195-M408 HydrophobicContact CE-CE 3.78Å; M195-M408 HydrophobicContact CE-SD 4.03Å; M195-M408 HydrophobicContact SD-CE 3.73Å; M195-M408 HydrophobicContact SD-SD 4.33Å; V205-M408 HydrophobicContact CG2-CG 4.38Å; V205-M408 HydrophobicContact CG2-SD 3.88Å; T206-M408 WeakPolarHBondContact CA-O 3.36Å; L207-M408 HydrophobicContact CB-CG 4.24Å; L207-M408 HydrophobicContact CD1-CE 4.41Å; L207-M408 HydrophobicContact CD1-CG 4.2Å; L207-M408 HydrophobicContact CD1-SD 4.48Å; L207-M408 HydrophobicContact CG-CG 4.18Å; L207-M408 PolarHBondContact N-O 2.91Å; L207-M408 PolarHBondContact O-N 3.14Å
409G98.4Very high98.5Very high27 Ų2734 Ų3428%0.27819%0.19SC..  trans85.7179.9-168.300000111.2
410R98.3Very high98.5Very high138 Ų13831.1 Ų31.152%0.52117%0.172SC..  trans-159.9154.9-179.559.6-162.2180-105.8-2.3110.5P399 F400 Q419P399-R410 HydrophobicContact CB-CB 3.94Å; P399-R410 HydrophobicContact CB-CG 4.05Å; F400-R410 CarbonylContact O-C 3.54Å; F400-R410 VanDerWaalsContact O-CA 3.23Å; F400-R410 WeakPolarHBondContact O-CA 3.22Å; R410-Q419 WeakPolarHBondContact O-CB 3.44Å; R410-Q419 WeakPolarHBondContact O-CG 2.99Å
411Y98.6Very high98.6Very high0 Ų030.9 Ų30.90%017%0.172CC..BIsolated β-bridgetrans-144-164.1175.981-67.1000111.4Q121 P122 F183 E208 F400 T416Q121-Y411 HydrophobicContact CB-CE2 4.1Å; Q121-Y411 HydrophobicContact CG-CD2 4.4Å; Q121-Y411 HydrophobicContact CG-CE2 3.84Å; P122-Y411 HydrophobicContact CG-CD2 4.49Å; P122-Y411 HydrophobicContact CG-CE2 4.3Å; F183-Y411 HydrophobicContact CE2-CD1 4.23Å; F183-Y411 HydrophobicContact CE2-CD2 4.37Å; F183-Y411 AromaticContact CE2-CG 3.95Å; F183-Y411 HydrophobicContact CE2-CG 3.95Å; F183-Y411 AromaticContact CZ-CD1 3.63Å; F183-Y411 HydrophobicContact CZ-CD1 3.63Å; F183-Y411 HydrophobicContact CZ-CD2 4.02Å; F183-Y411 AromaticContact CZ-CE1 3.92Å; F183-Y411 HydrophobicContact CZ-CE1 3.92Å; F183-Y411 HydrophobicContact CZ-CE2 4.36Å; F183-Y411 AromaticContact CZ-CG 3.69Å; F183-Y411 HydrophobicContact CZ-CG 3.69Å; E208-Y411 HydrophobicContact CG-CD1 4.12Å; E208-Y411 HydrophobicContact CG-CE1 3.79Å; E208-Y411 WeakPolarHBondContact OE1-CD1 3.48Å; F400-Y411 HydrophobicContact CD1-CD1 4.05Å; F400-Y411 AromaticContact CD1-CE1 3.34Å; F400-Y411 HydrophobicContact CD1-CE1 3.34Å; F400-Y411 AromaticContact CD1-CZ 3.9Å; F400-Y411 AromaticContact CE1-CE1 3.87Å; F400-Y411 HydrophobicContact CE1-CE1 3.87Å; F400-Y411 HydrophobicContact CG-CE1 4.45Å; F400-Y411 PolarHBondContact N-O 2.71Å; F400-Y411 PolarHBondContact O-N 3.45Å; Y411-T416 WeakPolarHBondContact CB-OG1 3.46Å
412H98Very high98.6Very high1 Ų134.8 Ų34.81%0.00519%0.188CC..SBendtrans85.5134.8-165.9-64.5-153.9000114.3E68 Q121 Y393 F400 K414 H415 T416E68-H412 WeakPolarHBondContact OE1-CA 3.49Å; Q121-H412 PolarHBondContact NE2-CD2 3.05Å; Q121-H412 PolarHBondContact NE2-CE1 3.32Å; Q121-H412 PolarHBondContact NE2-NE2 3.15Å; Q121-H412 VanDerWaalsContact NE2-NE2 3.16Å; Y393-H412 AromaticContact CD2-CE1 3.54Å; Y393-H412 AromaticContact CD2-NE2 3.95Å; Y393-H412 AromaticContact CE2-CE1 3.45Å; Y393-H412 VanDerWaalsContact CE2-CE1 3.45Å; Y393-H412 WeakPolarHBondContact CE2-CE1 3.34Å; Y393-H412 AromaticContact CE2-NE2 3.48Å; Y393-H412 WeakPolarHBondContact CE2-NE2 3.48Å; Y393-H412 AromaticContact CG-CE1 3.99Å; Y393-H412 AromaticContact CZ-CE1 3.81Å; Y393-H412 AromaticContact CZ-NE2 3.93Å; Y393-H412 PolarHBondContact O-CE1 3.42Å; Y393-H412 PolarHBondContact O-ND1 2.99Å; F400-H412 AromaticContact CD1-NE2 3.64Å; F400-H412 AromaticContact CG-NE2 3.81Å; H412-K414 PolarHBondContact O-N 3.35Å; H412-H415 WeakPolarHBondContact O-CA 3.47Å; H412-H415 VanDerWaalsContact O-CB 3.23Å; H412-H415 WeakPolarHBondContact O-CB 3.24Å; H412-H415 PolarHBondContact O-CD2 3Å; H412-H415 PolarHBondContact O-N 2.74Å; H412-T416 VanDerWaalsContact CA-OG1 3.29Å; H412-T416 WeakPolarHBondContact CA-OG1 3.49Å; H412-T416 PolarHBondContact N-OG1 3.43Å; H412-T416 PolarHBondContact O-N 3.36Å
413G97.9Very high98.6Very high3 Ų337.2 Ų37.23%0.03120%0.195CC..Hα-helixtrans44.9-122179.100000113.3E68 H415 T416 F417E68-G413 VanDerWaalsContact CD-N 3.32Å; E68-G413 PolarHBondContact OE1-N 2.94Å; E68-G413 PolarHBondContact OE2-N 3.15Å; G413-H415 PolarHBondContact O-N 2.87Å; G413-T416 PolarHBondContact O-N 3.31Å; G413-F417 PolarHBondContact O-N 2.99Å
414K98.4Very high98.6Very high70 Ų7040 Ų4030%0.30420%0.201SC..Hα-helixtrans-63.9-29.7179.2-170.7-176-178.3-51.70112.2W79 H412 F417 D418W79-K414 HydrophobicContact CD2-CB 4.39Å; W79-K414 HydrophobicContact CD2-CG 4.27Å; W79-K414 HydrophobicContact CG-CG 4.23Å; W79-K414 HydrophobicContact CZ2-CB 3.84Å; H412-K414 PolarHBondContact O-N 3.35Å; K414-F417 WeakPolarHBondContact O-CB 3.47Å; K414-F417 PolarHBondContact O-N 2.91Å; K414-D418 IonicContact NZ-OD1 3.98Å; K414-D418 PolarHBondContact NZ-OD1 2.84Å; K414-D418 IonicContact NZ-OD2 2.71Å; K414-D418 PolarHBondContact NZ-OD2 3.09Å; K414-D418 PolarHBondContact O-N 3.41Å
415H98.8Very high98.6Very high45 Ų4541.8 Ų41.821%0.20821%0.211CC..Hα-helixtrans-68-37.2-178.9-53.1-74.4000111S397 P399 H412 G413 D418 Q419S397-H415 PolarHBondContact O-NE2 3.32Å; P399-H415 HydrophobicContact CB-CB 4.39Å; H412-H415 WeakPolarHBondContact O-CA 3.47Å; H412-H415 VanDerWaalsContact O-CB 3.23Å; H412-H415 WeakPolarHBondContact O-CB 3.24Å; H412-H415 PolarHBondContact O-CD2 3Å; H412-H415 PolarHBondContact O-N 2.74Å; G413-H415 PolarHBondContact O-N 2.87Å; H415-D418 PolarHBondContact O-N 3.3Å; H415-Q419 WeakPolarHBondContact O-CB 3.36Å; H415-Q419 PolarHBondContact O-N 3.06Å
416T98.8Very high98.6Very high0 Ų039.6 Ų39.60%020%0.202CC..Hα-helixtrans-63.2-44.4171.6-37.80000111.3Y411 H412 G413 D418 Q419 L420Y411-T416 WeakPolarHBondContact CB-OG1 3.46Å; H412-T416 VanDerWaalsContact CA-OG1 3.29Å; H412-T416 WeakPolarHBondContact CA-OG1 3.49Å; H412-T416 PolarHBondContact N-OG1 3.43Å; H412-T416 PolarHBondContact O-N 3.36Å; G413-T416 PolarHBondContact O-N 3.31Å; T416-D418 PolarHBondContact O-N 3.11Å; T416-Q419 PolarHBondContact O-N 2.78Å; T416-L420 HydrophobicContact CG2-CD1 3.98Å; T416-L420 WeakPolarHBondContact O-CB 3.3Å; T416-L420 PolarHBondContact O-N 2.78Å
417F98.9Very high98.5Very high2 Ų243.8 Ų43.81%0.00922%0.224CC..Hα-helixtrans-58.5-48.1177.5175.6-84.4000111.4L76 W79 A80 P100 A128 A129 G413 K414 S421L76-F417 HydrophobicContact CD1-CD2 4.24Å; L76-F417 HydrophobicContact CD1-CE2 3.86Å; W79-F417 HydrophobicContact CB-CD1 3.86Å; W79-F417 HydrophobicContact CB-CD2 4.2Å; W79-F417 HydrophobicContact CB-CE1 3.84Å; W79-F417 HydrophobicContact CB-CE2 4.16Å; W79-F417 HydrophobicContact CB-CG 4.06Å; W79-F417 HydrophobicContact CB-CZ 4Å; W79-F417 HydrophobicContact CD2-CB 4.45Å; W79-F417 HydrophobicContact CD2-CG 4.45Å; W79-F417 HydrophobicContact CE3-CB 3.8Å; W79-F417 HydrophobicContact CE3-CD2 4.04Å; W79-F417 AromaticContact CE3-CG 3.95Å; W79-F417 HydrophobicContact CE3-CG 3.95Å; W79-F417 HydrophobicContact CZ3-CB 4.23Å; W79-F417 VanDerWaalsContact O-CE1 3.24Å; W79-F417 WeakPolarHBondContact O-CE1 3.22Å; A80-F417 HydrophobicContact CB-CZ 4.14Å; P100-F417 HydrophobicContact CB-CE1 3.8Å; P100-F417 HydrophobicContact CB-CZ 4.02Å; P100-F417 HydrophobicContact CG-CE1 4.19Å; A128-F417 HydrophobicContact CB-CD2 4.19Å; A128-F417 WeakPolarHBondContact O-CE2 3.43Å; A129-F417 HydrophobicContact CB-CD2 4.22Å; A129-F417 HydrophobicContact CB-CE2 4.47Å; G413-F417 PolarHBondContact O-N 2.99Å; K414-F417 WeakPolarHBondContact O-CB 3.47Å; K414-F417 PolarHBondContact O-N 2.91Å; F417-S421 VanDerWaalsContact O-CB 3.29Å; F417-S421 WeakPolarHBondContact O-CB 3.19Å; F417-S421 PolarHBondContact O-N 2.87Å; F417-S421 PolarHBondContact O-OG 3.22Å
418D98.8Very high98.4Very high38 Ų3847.6 Ų47.620%0.20324%0.242CC..Hα-helixtrans-66.5-43179.4-73.6-13.1000111.5R83 K414 H415 T416 L420 S421 H423R83-D418 IonicContact CZ-OD1 2.66Å; R83-D418 IonicContact NH1-OD1 3.16Å; R83-D418 PolarHBondContact NH1-OD1 3.36Å; R83-D418 IonicContact NH1-OD2 3.83Å; R83-D418 IonicContact NH2-OD1 3.72Å; R83-D418 PolarHBondContact NH2-OD1 3.19Å; K414-D418 IonicContact NZ-OD1 3.98Å; K414-D418 PolarHBondContact NZ-OD1 2.84Å; K414-D418 IonicContact NZ-OD2 2.71Å; K414-D418 PolarHBondContact NZ-OD2 3.09Å; K414-D418 PolarHBondContact O-N 3.41Å; H415-D418 PolarHBondContact O-N 3.3Å; T416-D418 PolarHBondContact O-N 3.11Å; D418-L420 VanDerWaalsContact C-N 3.27Å; D418-L420 PolarHBondContact O-N 2.81Å; D418-S421 PolarHBondContact O-N 2.96Å; D418-S421 VanDerWaalsContact O-O 3.05Å; D418-H423 WeakPolarHBondContact CB-NE2 3.37Å; D418-H423 IonicContact OD1-CE1 2.6Å; D418-H423 PolarHBondContact OD1-CE1 3.45Å; D418-H423 IonicContact OD1-NE2 2.7Å; D418-H423 PolarHBondContact OD1-NE2 3.04Å
419Q98.7Very high98.2Very high50 Ų5048.1 Ų48.123%0.23424%0.243CC..Hα-helixtrans-63.7-32.5-179.6-174.365.341.400112.5T206 R410 H415 T416T206-Q419 WeakPolarHBondContact OG1-CG 3.3Å; T206-Q419 PolarHBondContact OG1-NE2 3.26Å; R410-Q419 WeakPolarHBondContact O-CB 3.44Å; R410-Q419 WeakPolarHBondContact O-CG 2.99Å; H415-Q419 WeakPolarHBondContact O-CB 3.36Å; H415-Q419 PolarHBondContact O-N 3.06Å; T416-Q419 PolarHBondContact O-N 2.78Å
420L98.8Very high97.9Very high0 Ų050.6 Ų50.60%026%0.255CS..THydrogen-bonded Turntrans-101.318.4179.2-59.8-179.6000113.1V106 A126 A129 N131 H181 T416 D418V106-L420 HydrophobicContact CG1-CD2 4.15Å; V106-L420 HydrophobicContact CG2-CD2 4.29Å; A126-L420 HydrophobicContact CB-CD1 3.77Å; A129-L420 HydrophobicContact CB-CB 4.13Å; A129-L420 WeakPolarHBondContact CB-O 3.15Å; N131-L420 PolarHBondContact ND2-O 3.26Å; H181-L420 HydrophobicContact CB-CD2 4.16Å; H181-L420 WeakPolarHBondContact CD2-CD2 3.38Å; T416-L420 HydrophobicContact CG2-CD1 3.98Å; T416-L420 WeakPolarHBondContact O-CB 3.3Å; T416-L420 PolarHBondContact O-N 2.78Å; D418-L420 VanDerWaalsContact C-N 3.27Å; D418-L420 PolarHBondContact O-N 2.81Å
421S98.9Very high97.7Very high10 Ų1052.5 Ų52.57%0.0728%0.275CS..EExtended strand (participates in β ladder)trans-122.5147171.4-60.30000110.4E101 A129 F417 D418E101-S421 CarbonylContact O-C 3.53Å; E101-S421 VanDerWaalsContact O-CA 3.31Å; E101-S421 WeakPolarHBondContact O-CA 3.06Å; A129-S421 WeakPolarHBondContact CB-OG 3.42Å; F417-S421 VanDerWaalsContact O-CB 3.29Å; F417-S421 WeakPolarHBondContact O-CB 3.19Å; F417-S421 PolarHBondContact O-N 2.87Å; F417-S421 PolarHBondContact O-OG 3.22Å; D418-S421 PolarHBondContact O-N 2.96Å; D418-S421 VanDerWaalsContact O-O 3.05Å
422H98.8Very high97.1Very high92 Ų9254.5 Ų54.543%0.42630%0.296SS..EExtended strand (participates in β ladder)trans-83.3129.3160.9175.2-127.7000109.6P100 E101 L103 R424P100-H422 CarbonylContact C-O 3.49Å; P100-H422 WeakPolarHBondContact CA-O 3.39Å; E101-H422 HydrophobicContact CG-CB 3.89Å; E101-H422 PolarHBondContact N-O 2.86Å; E101-H422 PolarHBondContact O-N 3.32Å; E101-H422 IonicContact OE1-CE1 3.99Å; E101-H422 IonicContact OE1-CG 2.76Å; E101-H422 IonicContact OE1-ND1 3.65Å; E101-H422 PolarHBondContact OE1-ND1 3.39Å; L103-H422 HydrophobicContact CD2-CB 3.86Å; H422-R424 PolarHBondContact O-N 3.19Å
423H98.6Very high96.4Very high62 Ų6258.8 Ų58.829%0.28732%0.317SS..EExtended strand (participates in β ladder)trans-92.181.8176.2-77.6-57000110.6R83 I98 D418 A425R83-H423 VanDerWaalsContact CZ-CE1 3.41Å; R83-H423 PolarHBondContact NH1-CE1 3.29Å; R83-H423 PolarHBondContact NH2-CE1 3.49Å; I98-H423 HydrophobicContact CG2-CB 3.59Å; D418-H423 WeakPolarHBondContact CB-NE2 3.37Å; D418-H423 IonicContact OD1-CE1 2.6Å; D418-H423 PolarHBondContact OD1-CE1 3.45Å; D418-H423 IonicContact OD1-NE2 2.7Å; D418-H423 PolarHBondContact OD1-NE2 3.04Å; H423-A425 PolarHBondContact O-N 2.91Å
424R98.6Very high96Very high107 Ų10763.1 Ų63.140%0.40434%0.336SS..EExtended strand (participates in β ladder)trans-70.9119.4-174.7-169.9170.771.6-170.58.8111.9I98 L99 E101 H422I98-R424 CarbonylContact C-O 3.59Å; I98-R424 WeakPolarHBondContact CA-O 3.36Å; L99-R424 PolarHBondContact N-O 2.9Å; L99-R424 WeakPolarHBondContact O-CB 3.48Å; L99-R424 PolarHBondContact O-N 3.28Å; E101-R424 WeakPolarHBondContact OE1-CD 3.39Å; E101-R424 IonicContact OE1-NH1 3.06Å; E101-R424 IonicContact OE2-CZ 3.46Å; E101-R424 IonicContact OE2-NE 2.63Å; E101-R424 PolarHBondContact OE2-NE 3.45Å; E101-R424 IonicContact OE2-NH1 3.8Å; E101-R424 PolarHBondContact OE2-NH1 3.11Å; E101-R424 IonicContact OE2-NH2 3.16Å; H422-R424 PolarHBondContact O-N 3.19Å
425A98.4Very high95.2Very high88 Ų8864.6 Ų64.673%0.72735%0.354SS*.EExtended strand (participates in β ladder)trans-73129.9172.800000110.9H423H423-A425 PolarHBondContact O-N 2.91Å
426C98.1Very high94.3Very high16 Ų1667.8 Ų67.811%0.10837%0.372CS..EExtended strand (participates in β ladder)trans-124.2123.6179.2-62.60000110.2V96 Y97V96-C426 WeakPolarHBondContact CA-O 3.33Å; Y97-C426 HydrophobicContact CD1-CB 4.19Å; Y97-C426 HydrophobicContact CD2-CB 3.83Å; Y97-C426 HydrophobicContact CE1-CB 3.85Å; Y97-C426 HydrophobicContact CE2-CB 3.46Å; Y97-C426 VanDerWaalsContact CE2-CB 3.46Å; Y97-C426 HydrophobicContact CG-CB 4.18Å; Y97-C426 VanDerWaalsContact CZ-CB 3.47Å; Y97-C426 PolarHBondContact N-O 3.32Å; Y97-C426 VanDerWaalsContact N-O 3.07Å; Y97-C426 PolarHBondContact O-N 3.4Å
427L96.9Very high93.6Very high88 Ų8869 Ų6946%0.46138%0.378SS..EExtended strand (participates in β ladder)trans-122.7107.3172.3173.164.5000108.3T91 D94 Q95 V96 K429T91-L427 HydrophobicContact CG2-CD1 4.04Å; T91-L427 HydrophobicContact CG2-CD2 4.36Å; D94-L427 HydrophobicContact CB-CD1 3.54Å; Q95-L427 CarbonylContact O-C 3.49Å; Q95-L427 WeakPolarHBondContact O-CA 3.39Å; V96-L427 HydrophobicContact CG2-CD1 3.65Å; L427-K429 HydrophobicContact CG-CG 4.19Å
428I96.7Very high92.9Very high83 Ų8372.9 Ų72.943%0.42640%0.398SS..EExtended strand (participates in β ladder)trans-104.1110.7-179.6-43.4-58.6000108.4Q95 Y97Q95-I428 HydrophobicContact CB-CB 4.06Å; Q95-I428 HydrophobicContact CB-CG1 4.34Å; Q95-I428 PolarHBondContact N-O 2.84Å; Q95-I428 PolarHBondContact O-N 2.79Å; Y97-I428 HydrophobicContact CE1-CG1 4.11Å
429K94.2Very high92Very high91 Ų9172.5 Ų72.540%0.39640%0.399SS..  trans-98144.9176.2-56.2-168.264.563.20110.1D94 L427D94-K429 HydrophobicContact CB-CG 4.47Å; D94-K429 IonicContact OD1-NZ 3.47Å; D94-K429 PolarHBondContact OD1-NZ 3.41Å; D94-K429 IonicContact OD2-NZ 2.92Å; D94-K429 PolarHBondContact OD2-NZ 2.92Å; L427-K429 HydrophobicContact CG-CG 4.19Å
430S93.4Very high91.2Very high78 Ų7877.2 Ų77.255%0.54542%0.415SS..  trans-77.1161.2162.979.50000110.4G432S430-G432 PolarHBondContact O-N 2.63Å; S430-G432 PolarHBondContact OG-N 2.89Å; S430-G432 VanDerWaalsContact OG-N 3.16Å
431L92.8Very high90.6Very high179 Ų17980.3 Ų80.394%0.93743%0.427SS*.SBendtrans-77.14.2168.7-63.4177.3000113.1
432G87.8Confident89.9Confident42 Ų4285 Ų8543%0.43346%0.457SS..  trans-81.3168177.500000113.4S430 E434S430-G432 PolarHBondContact O-N 2.63Å; S430-G432 PolarHBondContact OG-N 2.89Å; S430-G432 VanDerWaalsContact OG-N 3.16Å; G432-E434 VanDerWaalsContact C-N 3.28Å; G432-E434 PolarHBondContact O-N 3.02Å
433M82.4Confident89.5Confident90 Ų9085.4 Ų85.444%0.44347%0.468SS..  trans58.931.5176.9-54.8179.8-6800114.9T93 C435 I436T93-M433 HydrophobicContact CG2-CE 3.82Å; T93-M433 HydrophobicContact CG2-SD 4.43Å; T93-M433 WeakPolarHBondContact OG1-CE 3.41Å; M433-C435 PolarHBondContact O-N 2.85Å; M433-C435 VanDerWaalsContact O-N 3.08Å; M433-I436 HydrophobicContact CB-CD1 3.72Å; M433-I436 HydrophobicContact CB-CG1 4.15Å; M433-I436 HydrophobicContact CG-CD1 4.33Å; M433-I436 WeakPolarHBondContact O-CB 3.47Å; M433-I436 PolarHBondContact O-N 2.95Å; M433-I436 HydrophobicContact SD-CD1 4.04Å
434E88.7Confident88.6Confident94 Ų9487 Ų8744%0.43948%0.476SS..Hα-helixtrans-58.3-26.6-178.5-176.260.6-177.900113.5G432 I436 N437 Y441G432-E434 VanDerWaalsContact C-N 3.28Å; G432-E434 PolarHBondContact O-N 3.02Å; E434-I436 PolarHBondContact O-N 3.48Å; E434-N437 WeakPolarHBondContact O-CB 3.47Å; E434-N437 PolarHBondContact O-N 2.96Å; E434-N437 PolarHBondContact OE2-ND2 3.05Å; E434-Y441 VanDerWaalsContact CD-OH 3.31Å; E434-Y441 WeakPolarHBondContact OE1-CE2 3.21Å; E434-Y441 PolarHBondContact OE1-OH 3.15Å; E434-Y441 PolarHBondContact OE2-OH 3Å
435C82.5Confident88Confident101 Ų10185.2 Ų85.268%0.68247%0.474SS*.Hα-helixtrans-58.6-29.3174.662.70000113.5M433 N437 M438M433-C435 PolarHBondContact O-N 2.85Å; M433-C435 VanDerWaalsContact O-N 3.08Å; C435-N437 PolarHBondContact O-N 3.49Å; C435-M438 VanDerWaalsContact O-CB 3.31Å; C435-M438 WeakPolarHBondContact O-CB 3.25Å; C435-M438 WeakPolarHBondContact O-CG 3.46Å; C435-M438 PolarHBondContact O-N 3.34Å
436I80.2Confident87.1Confident113 Ų11392.6 Ų92.658%0.57948%0.483SS*.Hα-helixtrans-65.7-32.7176.5-58.9180000110.3M433 E434 M438M433-I436 HydrophobicContact CB-CD1 3.72Å; M433-I436 HydrophobicContact CB-CG1 4.15Å; M433-I436 HydrophobicContact CG-CD1 4.33Å; M433-I436 WeakPolarHBondContact O-CB 3.47Å; M433-I436 PolarHBondContact O-N 2.95Å; M433-I436 HydrophobicContact SD-CD1 4.04Å; E434-I436 PolarHBondContact O-N 3.48Å; I436-M438 PolarHBondContact O-N 3.38Å
437N84.1Confident86.2Confident24 Ų2494.4 Ų94.413%0.12850%0.496CS..Hα-helixtrans-74.6-13-179.8-64.1-38000113.1E434 C435 A439 R440 Y441E434-N437 WeakPolarHBondContact O-CB 3.47Å; E434-N437 PolarHBondContact O-N 2.96Å; E434-N437 PolarHBondContact OE2-ND2 3.05Å; C435-N437 PolarHBondContact O-N 3.49Å; N437-A439 PolarHBondContact O-N 3.01Å; N437-A439 VanDerWaalsContact O-N 3.1Å; N437-R440 HydrophobicContact CB-CG 4.32Å; N437-R440 VanDerWaalsContact CG-NH2 3.25Å; N437-R440 PolarHBondContact ND2-NH2 2.91Å; N437-R440 WeakPolarHBondContact O-CG 3.38Å; N437-R440 PolarHBondContact O-N 3.47Å; N437-R440 VanDerWaalsContact OD1-CZ 3.24Å; N437-R440 PolarHBondContact OD1-NE 3.43Å; N437-R440 PolarHBondContact OD1-NH2 3.03Å; N437-Y441 HydrophobicContact CB-CD2 4.2Å; N437-Y441 HydrophobicContact CB-CE1 4Å; N437-Y441 HydrophobicContact CB-CE2 3.41Å; N437-Y441 VanDerWaalsContact CB-CE2 3.41Å; N437-Y441 VanDerWaalsContact CB-OH 3.27Å; N437-Y441 WeakPolarHBondContact CB-OH 3.2Å; N437-Y441 PolarHBondContact ND2-OH 3.36Å; N437-Y441 WeakPolarHBondContact O-CD2 3.49Å; N437-Y441 VanDerWaalsContact O-CG 3.31Å; N437-Y441 PolarHBondContact O-N 3.41Å
438M83.6Confident85.2Confident85 Ų8592.7 Ų92.742%0.41948%0.484SS..THydrogen-bonded Turntrans-58.3-27.7177.4-68.5-59.7-59.700113.3C435 I436 R440 Y441C435-M438 VanDerWaalsContact O-CB 3.31Å; C435-M438 WeakPolarHBondContact O-CB 3.25Å; C435-M438 WeakPolarHBondContact O-CG 3.46Å; C435-M438 PolarHBondContact O-N 3.34Å; I436-M438 PolarHBondContact O-N 3.38Å; M438-R440 VanDerWaalsContact C-N 3.3Å; M438-R440 PolarHBondContact O-N 3.16Å; M438-Y441 PolarHBondContact O-N 3.49Å; M438-Y441 HydrophobicContact SD-CD2 3.92Å
439A79.6Confident84.3Confident29 Ų2991.1 Ų91.124%0.2448%0.483CS..THydrogen-bonded Turntrans-67.7-28.5176.900000113.1N437 Q444 A452N437-A439 PolarHBondContact O-N 3.01Å; N437-A439 VanDerWaalsContact O-N 3.1Å; A439-Q444 PolarHBondContact O-NE2 3Å; A439-Q444 VanDerWaalsContact O-NE2 3.08Å; A439-A452 HydrophobicContact CB-CB 4.41Å
440R81.5Confident83.6Confident149 Ų14995.7 Ų95.756%0.56250%0.498SS*.THydrogen-bonded Turntrans-93.4-17.9176.961.6170.6-170.6-175.23.6113.3N437 M438 Q444N437-R440 HydrophobicContact CB-CG 4.32Å; N437-R440 VanDerWaalsContact CG-NH2 3.25Å; N437-R440 PolarHBondContact ND2-NH2 2.91Å; N437-R440 WeakPolarHBondContact O-CG 3.38Å; N437-R440 PolarHBondContact O-N 3.47Å; N437-R440 VanDerWaalsContact OD1-CZ 3.24Å; N437-R440 PolarHBondContact OD1-NE 3.43Å; N437-R440 PolarHBondContact OD1-NH2 3.03Å; M438-R440 VanDerWaalsContact C-N 3.3Å; M438-R440 PolarHBondContact O-N 3.16Å; R440-Q444 PolarHBondContact O-NE2 3.01Å
441Y86.1Confident82.6Confident66 Ų6698.7 Ų98.726%0.25950%0.497SS..SBendtrans-79.7142.3-177.3-62.6-29.6000114.1E434 N437 M438 Q444E434-Y441 VanDerWaalsContact CD-OH 3.31Å; E434-Y441 WeakPolarHBondContact OE1-CE2 3.21Å; E434-Y441 PolarHBondContact OE1-OH 3.15Å; E434-Y441 PolarHBondContact OE2-OH 3Å; N437-Y441 HydrophobicContact CB-CD2 4.2Å; N437-Y441 HydrophobicContact CB-CE1 4Å; N437-Y441 HydrophobicContact CB-CE2 3.41Å; N437-Y441 VanDerWaalsContact CB-CE2 3.41Å; N437-Y441 VanDerWaalsContact CB-OH 3.27Å; N437-Y441 WeakPolarHBondContact CB-OH 3.2Å; N437-Y441 PolarHBondContact ND2-OH 3.36Å; N437-Y441 WeakPolarHBondContact O-CD2 3.49Å; N437-Y441 VanDerWaalsContact O-CG 3.31Å; N437-Y441 PolarHBondContact O-N 3.41Å; M438-Y441 PolarHBondContact O-N 3.49Å; M438-Y441 HydrophobicContact SD-CD2 3.92Å; Y441-Q444 PolarHBondContact O-NE2 3.12Å
442P86.1Confident81.7Confident108 Ų10891 Ų9170%0.70146%0.46SS*.SBendtrans-64.5158.5166.3-21.534000113.4
443P88.6Confident81.1Confident101 Ų10196 Ų9666%0.65647%0.466SS*.SBendcis-69143.8-8.829.8-34.3000111R448P443-R448 WeakPolarHBondContact O-CD 3.17Å; P443-R448 PolarHBondContact O-NH1 3.15Å
444Q81.3Confident80.6Confident94 Ų9497.9 Ų97.944%0.43947%0.473SS..PPolyproline II helixtrans-86.6131.3174.8-74.3-66.3-18.400109.6A439 R440 Y441A439-Q444 PolarHBondContact O-NE2 3Å; A439-Q444 VanDerWaalsContact O-NE2 3.08Å; R440-Q444 PolarHBondContact O-NE2 3.01Å; Y441-Q444 PolarHBondContact O-NE2 3.12Å
445D84.8Confident79.6Confident71 Ų7196 Ų9638%0.3847%0.474SS..  trans-125.1168.8173.568.848.9000109.9S447 R448 A449D445-S447 PolarHBondContact O-N 3Å; D445-S447 VanDerWaalsContact O-N 3.16Å; D445-S447 VanDerWaalsContact OD1-CA 3.25Å; D445-S447 WeakPolarHBondContact OD1-CA 3.29Å; D445-S447 WeakPolarHBondContact OD1-CB 3.47Å; D445-S447 PolarHBondContact OD1-N 3.13Å; D445-S447 PolarHBondContact OD1-OG 3.26Å; D445-R448 PolarHBondContact O-N 3.35Å; D445-R448 PolarHBondContact OD1-N 3.03Å; D445-R448 IonicContact OD2-NE 3.53Å; D445-R448 PolarHBondContact OD2-NE 2.91Å; D445-A449 WeakPolarHBondContact O-CB 3.35Å; D445-A449 PolarHBondContact O-N 2.77Å
446R80.1Confident78.9Confident242 Ų24297.3 Ų97.391%0.91347%0.471SS*.Hα-helixtrans-55.9-33.8-179.5-74.7-174.4177.2-169.80.1112.8R450R446-R450 WeakPolarHBondContact O-CB 3.22Å; R446-R450 PolarHBondContact O-N 3.2Å
447S78.5Confident78.2Confident55 Ų55100.2 Ų100.239%0.38548%0.475SS..Hα-helixtrans-73.3-41.5-179.785.70000112.1D445 R451D445-S447 PolarHBondContact O-N 3Å; D445-S447 VanDerWaalsContact O-N 3.16Å; D445-S447 VanDerWaalsContact OD1-CA 3.25Å; D445-S447 WeakPolarHBondContact OD1-CA 3.29Å; D445-S447 WeakPolarHBondContact OD1-CB 3.47Å; D445-S447 PolarHBondContact OD1-N 3.13Å; D445-S447 PolarHBondContact OD1-OG 3.26Å; S447-R451 WeakPolarHBondContact O-CG 3.4Å; S447-R451 PolarHBondContact O-N 2.76Å; S447-R451 PolarHBondContact O-NE 3.33Å; S447-R451 PolarHBondContact OG-NH2 2.8Å
448R77.1Confident76.8Confident52 Ų52100.7 Ų100.720%0.19648%0.481CS..Hα-helixtrans-70.2-45.9177.8-68.3179.7-172.8-160.8-4110.6P443 D445 R450 R451 A452P443-R448 WeakPolarHBondContact O-CD 3.17Å; P443-R448 PolarHBondContact O-NH1 3.15Å; D445-R448 PolarHBondContact O-N 3.35Å; D445-R448 PolarHBondContact OD1-N 3.03Å; D445-R448 IonicContact OD2-NE 3.53Å; D445-R448 PolarHBondContact OD2-NE 2.91Å; R448-R450 VanDerWaalsContact C-N 3.33Å; R448-R450 PolarHBondContact O-N 3.3Å; R448-R451 PolarHBondContact O-N 3.04Å; R448-A452 WeakPolarHBondContact O-CB 3.47Å; R448-A452 PolarHBondContact O-N 3.11Å
449A77.7Confident74.9Confident50 Ų50101.5 Ų101.541%0.41349%0.494SS..Hα-helixtrans-60.3-40.9175.400000112.1D445 R453D445-A449 WeakPolarHBondContact O-CB 3.35Å; D445-A449 PolarHBondContact O-N 2.77Å; A449-R453 WeakPolarHBondContact O-CB 3.28Å; A449-R453 PolarHBondContact O-N 3.16Å
450R79.5Confident73.5Confident186 Ų186105 Ų10570%0.70251%0.509SS*.Hα-helixtrans-63.4-46.3174.4177.1177.8148.5-175-6.8112R446 R448 R453 Q454R446-R450 WeakPolarHBondContact O-CB 3.22Å; R446-R450 PolarHBondContact O-N 3.2Å; R448-R450 VanDerWaalsContact C-N 3.33Å; R448-R450 PolarHBondContact O-N 3.3Å; R450-R453 PolarHBondContact O-N 2.79Å; R450-Q454 WeakPolarHBondContact O-CB 3.28Å; R450-Q454 PolarHBondContact O-N 3.14Å
451R72.3Confident71.8Confident141 Ų141101.6 Ų101.653%0.53251%0.507SS..Hα-helixtrans-62.6-46.3177.3-78.3-179.2-74.6-165.1-2.5112.1S447 R448 R453 Q454 A455S447-R451 WeakPolarHBondContact O-CG 3.4Å; S447-R451 PolarHBondContact O-N 2.76Å; S447-R451 PolarHBondContact O-NE 3.33Å; S447-R451 PolarHBondContact OG-NH2 2.8Å; R448-R451 PolarHBondContact O-N 3.04Å; R451-R453 VanDerWaalsContact C-N 3.35Å; R451-R453 PolarHBondContact O-N 3.2Å; R451-Q454 PolarHBondContact O-N 2.92Å; R451-A455 WeakPolarHBondContact O-CB 3.43Å; R451-A455 PolarHBondContact O-N 3.35Å
452A73.5Confident69.9Low19 Ų19105.6 Ų105.616%0.15753%0.532CS..Hα-helixtrans-60.3-44.417600000111.4A439 R448 Q454 A455 M456A439-A452 HydrophobicContact CB-CB 4.41Å; R448-A452 WeakPolarHBondContact O-CB 3.47Å; R448-A452 PolarHBondContact O-N 3.11Å; A452-Q454 VanDerWaalsContact C-N 3.34Å; A452-Q454 PolarHBondContact O-N 2.94Å; A452-A455 PolarHBondContact O-N 2.78Å; A452-M456 HydrophobicContact CB-CE 4.14Å; A452-M456 WeakPolarHBondContact O-CB 3.49Å; A452-M456 WeakPolarHBondContact O-CE 3.49Å; A452-M456 WeakPolarHBondContact O-CG 3.17Å; A452-M456 PolarHBondContact O-N 3.23Å
453R75.3Confident67.8Low147 Ų147106.4 Ų106.456%0.55553%0.527SS*.Hα-helixtrans-64.2-38177.2-163.1179.5-145.6168.75112.4A449 R450 R451 R457A449-R453 WeakPolarHBondContact O-CB 3.28Å; A449-R453 PolarHBondContact O-N 3.16Å; R450-R453 PolarHBondContact O-N 2.79Å; R451-R453 VanDerWaalsContact C-N 3.35Å; R451-R453 PolarHBondContact O-N 3.2Å; R453-R457 HydrophobicContact CG-CG 4.38Å; R453-R457 WeakPolarHBondContact O-CB 3.42Å; R453-R457 VanDerWaalsContact O-CG 3.23Å; R453-R457 WeakPolarHBondContact O-CG 3.34Å; R453-R457 PolarHBondContact O-N 2.9Å
454Q71.4Confident66Low129 Ų129105.9 Ų105.960%0.60353%0.526SS*.Hα-helixtrans-68.4-42.1176.4-172.4170.7-0.900111.7R450 R451 A452 M456 R457 S458R450-Q454 WeakPolarHBondContact O-CB 3.28Å; R450-Q454 PolarHBondContact O-N 3.14Å; R451-Q454 PolarHBondContact O-N 2.92Å; A452-Q454 VanDerWaalsContact C-N 3.34Å; A452-Q454 PolarHBondContact O-N 2.94Å; Q454-M456 VanDerWaalsContact C-N 3.35Å; Q454-M456 PolarHBondContact O-N 2.89Å; Q454-R457 PolarHBondContact O-N 3.02Å; Q454-S458 PolarHBondContact O-N 3.04Å; Q454-S458 VanDerWaalsContact O-N 3.13Å
455A68.1Low64.6Low55 Ų55110.1 Ų110.146%0.45554%0.543SS..Hα-helixtrans-64.6-36.4175.300000112.8R451 A452 S458R451-A455 WeakPolarHBondContact O-CB 3.43Å; R451-A455 PolarHBondContact O-N 3.35Å; A452-A455 PolarHBondContact O-N 2.78Å; A455-S458 PolarHBondContact O-OG 3.2Å
456M67.4Low63Low127 Ų127109.7 Ų109.763%0.62655%0.545SS*.Hα-helixtrans-79.5-24.7176.9-71.1-174.4-74.700113.9A452 Q454A452-M456 HydrophobicContact CB-CE 4.14Å; A452-M456 WeakPolarHBondContact O-CB 3.49Å; A452-M456 WeakPolarHBondContact O-CE 3.49Å; A452-M456 WeakPolarHBondContact O-CG 3.17Å; A452-M456 PolarHBondContact O-N 3.23Å; Q454-M456 VanDerWaalsContact C-N 3.35Å; Q454-M456 PolarHBondContact O-N 2.89Å
457R65.8Low61.9Low174 Ų174100.5 Ų100.566%0.65752%0.516SS*.Hα-helixtrans-92.8-14.3-178.4-78.4-177.1172.6178-7.8114.6R453 Q454 S459R453-R457 HydrophobicContact CG-CG 4.38Å; R453-R457 WeakPolarHBondContact O-CB 3.42Å; R453-R457 VanDerWaalsContact O-CG 3.23Å; R453-R457 WeakPolarHBondContact O-CG 3.34Å; R453-R457 PolarHBondContact O-N 2.9Å; Q454-R457 PolarHBondContact O-N 3.02Å; R457-S459 PolarHBondContact O-N 2.74Å; R457-S459 VanDerWaalsContact O-N 3.12Å
458S53.9Low61Low35 Ų35104.1 Ų104.125%0.24553%0.525CS..  trans-60.4121.2-179.8580000109.6Q454 A455 L460 C461Q454-S458 PolarHBondContact O-N 3.04Å; Q454-S458 VanDerWaalsContact O-N 3.13Å; A455-S458 PolarHBondContact O-OG 3.2Å; S458-L460 PolarHBondContact O-N 3.48Å; S458-C461 PolarHBondContact O-N 2.92Å
459S45Very low60.1Low101 Ų101105.3 Ų105.371%0.70654%0.538SS*.G310 helixtrans-58.2-0.8175.854.80000114.5R457 C461 D462R457-S459 PolarHBondContact O-N 2.74Å; R457-S459 VanDerWaalsContact O-N 3.12Å; S459-C461 PolarHBondContact O-N 3.42Å; S459-D462 PolarHBondContact O-N 2.92Å
460L48.7Very low59.4Low103 Ų103111.1 Ų111.154%0.53955%0.55SS..G310 helixtrans-65.8-7164.8-66.1168.2000113.2S458 D462S458-L460 PolarHBondContact O-N 3.48Å; L460-D462 PolarHBondContact O-N 3.25Å
461C46.6Very low58.7Low77 Ų77104.7 Ų104.752%0.5254%0.536SS..G310 helixtrans-70.2-9.2169.6-137.30000113.3S458 S459S458-C461 PolarHBondContact O-N 2.92Å; S459-C461 PolarHBondContact O-N 3.42Å
462D45.6Very low58.6Low150 Ų150101 Ų10180%0.80253%0.529SS*.SBendtrans-132.511.1-172.1-152.416.2000114.1S459 L460S459-D462 PolarHBondContact O-N 2.92Å; L460-D462 PolarHBondContact O-N 3.25Å
463Q43Very low58.3Low126 Ų126103.9 Ų103.959%0.58954%0.542SS*.  trans-118.7101.2176.4-71.1-159.7-16.200112
464S50Low58.2Low90 Ų9099.6 Ų99.663%0.62954%0.537SS*.  trans-4.9141.3146.9165.30000116S466 T467S464-S466 PolarHBondContact O-N 3.01Å; S464-T467 PolarHBondContact O-N 2.96Å; S464-T467 PolarHBondContact O-OG1 3.17Å
465K52.8Low58.6Low182 Ų18297.5 Ų97.579%0.79153%0.534SS*.THydrogen-bonded Turntrans-30.3-26.9171.4-65176178.7175.30116.5V469K465-V469 WeakPolarHBondContact O-CB 3.35Å; K465-V469 VanDerWaalsContact O-CG2 3.22Å; K465-V469 WeakPolarHBondContact O-CG2 3.35Å; K465-V469 PolarHBondContact O-N 3.34Å; K465-V469 VanDerWaalsContact O-N 3.16Å
466S51.5Low59.2Low62 Ų62100.1 Ų100.143%0.43454%0.539SS..Hα-helixtrans-52.3-54.6175.5-178.50000113.6S464 F468 V469 W470S464-S466 PolarHBondContact O-N 3.01Å; S466-F468 PolarHBondContact O-N 2.91Å; S466-V469 PolarHBondContact O-N 3.4Å; S466-W470 PolarHBondContact O-N 3Å
467T55.6Low59.8Low50 Ų5099.5 Ų99.531%0.30754%0.537SS..Hα-helixtrans-71.3-33.2-17240.80000113.5S464 A471S464-T467 PolarHBondContact O-N 2.96Å; S464-T467 PolarHBondContact O-OG1 3.17Å; T467-A471 VanDerWaalsContact O-CB 3.32Å; T467-A471 WeakPolarHBondContact O-CB 3.08Å; T467-A471 PolarHBondContact O-N 3.3Å
468F59.2Low60.5Low131 Ų13194 Ų9458%0.57553%0.529SS*.Hα-helixtrans-69.1-40.9174.4-171.7-98.9000112S466 A471 V472S466-F468 PolarHBondContact O-N 2.91Å; F468-A471 PolarHBondContact O-N 3.37Å; F468-V472 HydrophobicContact CD1-CG2 4.18Å; F468-V472 HydrophobicContact CE1-CG2 3.82Å; F468-V472 HydrophobicContact CZ-CG2 4.03Å; F468-V472 WeakPolarHBondContact O-CG2 3.08Å; F468-V472 PolarHBondContact O-N 2.99Å
469V59Low61.9Low77 Ų7795.8 Ų95.847%0.46754%0.54SS..Hα-helixtrans-63.5-42.8175.4170.40000111K465 S466 V472 L473K465-V469 WeakPolarHBondContact O-CB 3.35Å; K465-V469 VanDerWaalsContact O-CG2 3.22Å; K465-V469 WeakPolarHBondContact O-CG2 3.35Å; K465-V469 PolarHBondContact O-N 3.34Å; K465-V469 VanDerWaalsContact O-N 3.16Å; S466-V469 PolarHBondContact O-N 3.4Å; V469-V472 PolarHBondContact O-N 3.5Å; V469-L473 HydrophobicContact CG1-CD1 3.84Å; V469-L473 WeakPolarHBondContact O-CB 3.37Å; V469-L473 WeakPolarHBondContact O-CG 3.44Å; V469-L473 PolarHBondContact O-N 3.03Å
470W62.2Low63.7Low172 Ų17292.9 Ų92.965%0.65253%0.527SS*.Hα-helixtrans-65.7-37.2175.1-76.3114.5000112.9S466 L473 A474S466-W470 PolarHBondContact O-N 3Å; W470-L473 HydrophobicContact CE3-CD1 4.46Å; W470-A474 WeakPolarHBondContact O-CB 3.29Å; W470-A474 PolarHBondContact O-N 3.16Å
471A64.9Low65.5Low51 Ų5193.6 Ų93.642%0.42153%0.53SS..Hα-helixtrans-66.4-42.1175.800000112.1T467 F468 A474 T475T467-A471 VanDerWaalsContact O-CB 3.32Å; T467-A471 WeakPolarHBondContact O-CB 3.08Å; T467-A471 PolarHBondContact O-N 3.3Å; F468-A471 PolarHBondContact O-N 3.37Å; A471-A474 PolarHBondContact O-N 3.02Å; A471-T475 WeakPolarHBondContact O-CB 3.46Å; A471-T475 PolarHBondContact O-N 3.37Å; A471-T475 PolarHBondContact O-OG1 3.21Å
472V70.1Confident67.2Low63 Ų6395.2 Ų95.238%0.38253%0.534SS..Hα-helixtrans-66.1-45.1175.9172.60000110.8F468 V469 A474 T475 I476F468-V472 HydrophobicContact CD1-CG2 4.18Å; F468-V472 HydrophobicContact CE1-CG2 3.82Å; F468-V472 HydrophobicContact CZ-CG2 4.03Å; F468-V472 WeakPolarHBondContact O-CG2 3.08Å; F468-V472 PolarHBondContact O-N 2.99Å; V469-V472 PolarHBondContact O-N 3.5Å; V472-A474 PolarHBondContact O-N 3.39Å; V472-T475 PolarHBondContact O-N 2.96Å; V472-I476 HydrophobicContact CG1-CD1 3.88Å; V472-I476 WeakPolarHBondContact O-CG1 3.32Å; V472-I476 PolarHBondContact O-N 2.94Å
473L68.8Low69.1Low80 Ų8092.4 Ų92.442%0.41952%0.522SS..Hα-helixtrans-61-43.6175.6-78.1167.1000112V469 W470 T475 I476 L477V469-L473 HydrophobicContact CG1-CD1 3.84Å; V469-L473 WeakPolarHBondContact O-CB 3.37Å; V469-L473 WeakPolarHBondContact O-CG 3.44Å; V469-L473 PolarHBondContact O-N 3.03Å; W470-L473 HydrophobicContact CE3-CD1 4.46Å; L473-T475 VanDerWaalsContact C-N 3.3Å; L473-T475 PolarHBondContact O-N 2.93Å; L473-I476 PolarHBondContact O-N 3.08Å; L473-L477 WeakPolarHBondContact O-CB 3.39Å; L473-L477 PolarHBondContact O-N 3.37Å
474A72.3Confident70.8Confident56 Ų5688.6 Ų88.646%0.46351%0.511SS..Hα-helixtrans-63.2-37.4176.300000111.9W470 A471 V472 L477 A478W470-A474 WeakPolarHBondContact O-CB 3.29Å; W470-A474 PolarHBondContact O-N 3.16Å; A471-A474 PolarHBondContact O-N 3.02Å; V472-A474 PolarHBondContact O-N 3.39Å; A474-L477 PolarHBondContact O-N 3.37Å; A474-A478 VanDerWaalsContact O-CB 3.28Å; A474-A478 WeakPolarHBondContact O-CB 3.48Å; A474-A478 PolarHBondContact O-N 3.36Å
475T79.7Confident72.3Confident86 Ų8689.8 Ų89.853%0.52851%0.51SS..Hα-helixtrans-69.4-41.4177.3-50.30000111.4A471 V472 L473 A478 C479A471-T475 WeakPolarHBondContact O-CB 3.46Å; A471-T475 PolarHBondContact O-N 3.37Å; A471-T475 PolarHBondContact O-OG1 3.21Å; V472-T475 PolarHBondContact O-N 2.96Å; L473-T475 VanDerWaalsContact C-N 3.3Å; L473-T475 PolarHBondContact O-N 2.93Å; T475-A478 PolarHBondContact O-N 2.73Å; T475-C479 WeakPolarHBondContact O-CB 3.5Å; T475-C479 PolarHBondContact O-N 2.93Å; T475-C479 PolarHBondContact O-SG 2.92Å; T475-C479 VanDerWaalsContact O-SG 3.38Å
476I81.1Confident73.7Confident110 Ų11085.8 Ų85.856%0.56450%0.496SS*.Hα-helixtrans-63.8-43.8175.1-67.5168.2000110.6V472 L473 C479 G480V472-I476 HydrophobicContact CG1-CD1 3.88Å; V472-I476 WeakPolarHBondContact O-CG1 3.32Å; V472-I476 PolarHBondContact O-N 2.94Å; L473-I476 PolarHBondContact O-N 3.08Å; I476-C479 PolarHBondContact O-N 3.4Å; I476-G480 PolarHBondContact O-N 3.11Å
477L79.6Confident75.1Confident114 Ų11486.2 Ų86.260%0.59750%0.496SS*.Hα-helixtrans-61.6-43.7174.9-99.8148000112.2L473 A474 G480 L481L473-L477 WeakPolarHBondContact O-CB 3.39Å; L473-L477 PolarHBondContact O-N 3.37Å; A474-L477 PolarHBondContact O-N 3.37Å; L477-G480 PolarHBondContact O-N 3.25Å; L477-L481 WeakPolarHBondContact O-CB 3.4Å; L477-L481 WeakPolarHBondContact O-CG 3.21Å; L477-L481 PolarHBondContact O-N 3.32Å
478A80.8Confident76.3Confident57 Ų5789.6 Ų89.647%0.47151%0.511SS..Hα-helixtrans-64.1-43.8177.300000111.8A474 T475 L481 L482A474-A478 VanDerWaalsContact O-CB 3.28Å; A474-A478 WeakPolarHBondContact O-CB 3.48Å; A474-A478 PolarHBondContact O-N 3.36Å; T475-A478 PolarHBondContact O-N 2.73Å; A478-L481 PolarHBondContact O-N 3.08Å; A478-L482 WeakPolarHBondContact O-CB 3.4Å; A478-L482 PolarHBondContact O-N 3.1Å
479C83.8Confident77.2Confident73 Ų7388 Ų8849%0.49351%0.512SS..Hα-helixtrans-62.7-41.6173.6-73.60000111.8T475 I476 L482 V483T475-C479 WeakPolarHBondContact O-CB 3.5Å; T475-C479 PolarHBondContact O-N 2.93Å; T475-C479 PolarHBondContact O-SG 2.92Å; T475-C479 VanDerWaalsContact O-SG 3.38Å; I476-C479 PolarHBondContact O-N 3.4Å; C479-L482 PolarHBondContact O-N 2.85Å; C479-V483 VanDerWaalsContact O-CG2 3.31Å; C479-V483 WeakPolarHBondContact O-CG2 3.47Å; C479-V483 PolarHBondContact O-N 2.83Å
480G83.4Confident78Confident41 Ų4189.1 Ų89.142%0.42352%0.519SS..Hα-helixtrans-63.1-43.1176.300000113I476 L477 V483 A484I476-G480 PolarHBondContact O-N 3.11Å; L477-G480 PolarHBondContact O-N 3.25Å; G480-V483 PolarHBondContact O-N 2.96Å; G480-A484 WeakPolarHBondContact O-CB 3.35Å; G480-A484 PolarHBondContact O-N 3.23Å
481L85Confident78.4Confident117 Ų11787.5 Ų87.561%0.61352%0.52SS*.Hα-helixtrans-64.3-40.1174.3-80.2163.8000111.8L477 A478 A484 L485L477-L481 WeakPolarHBondContact O-CB 3.4Å; L477-L481 WeakPolarHBondContact O-CG 3.21Å; L477-L481 PolarHBondContact O-N 3.32Å; A478-L481 PolarHBondContact O-N 3.08Å; L481-A484 PolarHBondContact O-N 2.9Å; L481-L485 WeakPolarHBondContact O-CB 3.41Å; L481-L485 PolarHBondContact O-N 3.26Å
482L83.4Confident78.2Confident112 Ų11288.4 Ų88.459%0.58653%0.534SS*.Hα-helixtrans-62.6-43.7176.5-16084.6000111.3A478 C479 L485 I486A478-L482 WeakPolarHBondContact O-CB 3.4Å; A478-L482 PolarHBondContact O-N 3.1Å; C479-L482 PolarHBondContact O-N 2.85Å; L482-L485 PolarHBondContact O-N 3.09Å; L482-I486 HydrophobicContact CG-CD1 4.41Å; L482-I486 WeakPolarHBondContact O-CD1 3.32Å; L482-I486 VanDerWaalsContact O-CG1 3.24Å; L482-I486 WeakPolarHBondContact O-CG1 3.31Å; L482-I486 PolarHBondContact O-N 2.73Å
483V84.4Confident77.6Confident91 Ų9189.4 Ų89.455%0.55255%0.549SS*.Hα-helixtrans-63.6-44.1175.61720000110.9C479 G480 L485 I486 V487C479-V483 VanDerWaalsContact O-CG2 3.31Å; C479-V483 WeakPolarHBondContact O-CG2 3.47Å; C479-V483 PolarHBondContact O-N 2.83Å; G480-V483 PolarHBondContact O-N 2.96Å; V483-L485 VanDerWaalsContact C-N 3.33Å; V483-L485 PolarHBondContact O-N 3.41Å; V483-I486 PolarHBondContact O-N 3.11Å; V483-V487 WeakPolarHBondContact O-CG2 3.42Å; V483-V487 PolarHBondContact O-N 3.44Å
484A78.7Confident76.6Confident45 Ų4599.7 Ų99.737%0.37258%0.582SS.*Hα-helixtrans-62.1-40.3176.800000112.3G480 L481 V487 I488G480-A484 WeakPolarHBondContact O-CB 3.35Å; G480-A484 PolarHBondContact O-N 3.23Å; L481-A484 PolarHBondContact O-N 2.9Å; A484-V487 PolarHBondContact O-N 3.18Å; A484-I488 WeakPolarHBondContact O-CG1 3.17Å; A484-I488 PolarHBondContact O-N 2.77Å
485L81.8Confident76.8Confident116 Ų116101.9 Ų101.961%0.60759%0.588SS**Hα-helixtrans-64.6-42177.1-141.8108.5000111.5L481 L482 V483 V487 I488 V489L481-L485 WeakPolarHBondContact O-CB 3.41Å; L481-L485 PolarHBondContact O-N 3.26Å; L482-L485 PolarHBondContact O-N 3.09Å; V483-L485 VanDerWaalsContact C-N 3.33Å; V483-L485 PolarHBondContact O-N 3.41Å; L485-V487 VanDerWaalsContact C-N 3.33Å; L485-V487 PolarHBondContact O-N 3.12Å; L485-I488 PolarHBondContact O-N 3.07Å; L485-V489 VanDerWaalsContact O-CG2 3.3Å; L485-V489 WeakPolarHBondContact O-CG2 3.3Å; L485-V489 PolarHBondContact O-N 3.24Å
486I82.4Confident76.7Confident97 Ų97102.7 Ų102.750%0.49759%0.592SS.*Hα-helixtrans-61.1-43.3174.8-69.4165000110.4L482 V483 V489 V490L482-I486 HydrophobicContact CG-CD1 4.41Å; L482-I486 WeakPolarHBondContact O-CD1 3.32Å; L482-I486 VanDerWaalsContact O-CG1 3.24Å; L482-I486 WeakPolarHBondContact O-CG1 3.31Å; L482-I486 PolarHBondContact O-N 2.73Å; V483-I486 PolarHBondContact O-N 3.11Å; I486-V489 PolarHBondContact O-N 3.28Å; I486-V490 HydrophobicContact CG2-CG2 4.38Å; I486-V490 WeakPolarHBondContact O-CB 3.19Å; I486-V490 WeakPolarHBondContact O-CG2 3.15Å; I486-V490 PolarHBondContact O-N 3.33Å
487V80Confident76.4Confident71 Ų71102.3 Ų102.343%0.4359%0.593SS.*Hα-helixtrans-63.2-43.1177.6171.90000111.6V483 A484 L485 V490 M491V483-V487 WeakPolarHBondContact O-CG2 3.42Å; V483-V487 PolarHBondContact O-N 3.44Å; A484-V487 PolarHBondContact O-N 3.18Å; L485-V487 VanDerWaalsContact C-N 3.33Å; L485-V487 PolarHBondContact O-N 3.12Å; V487-V490 PolarHBondContact O-N 2.92Å; V487-M491 HydrophobicContact CG1-CG 4.29Å; V487-M491 HydrophobicContact CG1-SD 3.68Å; V487-M491 WeakPolarHBondContact O-CB 3.4Å; V487-M491 WeakPolarHBondContact O-CG 3.31Å; V487-M491 PolarHBondContact O-N 2.67Å
488I81.4Confident76.3Confident121 Ų121101.6 Ų101.662%0.62159%0.593SS**Hα-helixtrans-64-43.6178-69.3167.6000111.3A484 L485 V490 M491 G492A484-I488 WeakPolarHBondContact O-CG1 3.17Å; A484-I488 PolarHBondContact O-N 2.77Å; L485-I488 PolarHBondContact O-N 3.07Å; I488-V490 VanDerWaalsContact C-N 3.33Å; I488-V490 PolarHBondContact O-N 3.28Å; I488-M491 PolarHBondContact O-N 3.34Å; I488-G492 PolarHBondContact O-N 2.62Å
489V79.2Confident76Confident99 Ų99104.4 Ų104.460%0.660%0.6SS**Hα-helixtrans-64.9-38.1178.2171.70000111.4L485 I486 A493L485-V489 VanDerWaalsContact O-CG2 3.3Å; L485-V489 WeakPolarHBondContact O-CG2 3.3Å; L485-V489 PolarHBondContact O-N 3.24Å; I486-V489 PolarHBondContact O-N 3.28Å; V489-A493 WeakPolarHBondContact O-CB 3.34Å
490V74.9Confident75.4Confident99 Ų99106.5 Ų106.560%0.661%0.608SS**Hα-helixtrans-74.8-33.7178.9172.40000112.3I486 V487 I488I486-V490 HydrophobicContact CG2-CG2 4.38Å; I486-V490 WeakPolarHBondContact O-CB 3.19Å; I486-V490 WeakPolarHBondContact O-CG2 3.15Å; I486-V490 PolarHBondContact O-N 3.33Å; V487-V490 PolarHBondContact O-N 2.92Å; I488-V490 VanDerWaalsContact C-N 3.33Å; I488-V490 PolarHBondContact O-N 3.28Å
491M69.9Low74.9Confident139 Ų139111.1 Ų111.169%0.68562%0.621SS**Hα-helixtrans-84.9-27.6179.4-70.7-176.264.700113.9V487 I488 A493V487-M491 HydrophobicContact CG1-CG 4.29Å; V487-M491 HydrophobicContact CG1-SD 3.68Å; V487-M491 WeakPolarHBondContact O-CB 3.4Å; V487-M491 WeakPolarHBondContact O-CG 3.31Å; V487-M491 PolarHBondContact O-N 2.67Å; I488-M491 PolarHBondContact O-N 3.34Å; M491-A493 VanDerWaalsContact C-N 3.29Å
492G60.6Low74.1Confident70 Ų70110.7 Ų110.772%0.72262%0.621SS**THydrogen-bonded Turntrans-80.2-5.6175.400000114.6I488I488-G492 PolarHBondContact O-N 2.62Å
493A57.6Low73.3Confident84 Ų84110.6 Ų110.669%0.69462%0.624SS**THydrogen-bonded Turntrans-9620.7176.500000113.3V489 M491V489-A493 WeakPolarHBondContact O-CB 3.34Å; M491-A493 VanDerWaalsContact C-N 3.29Å
494R49.2Very low72.3Confident295 Ų295112.4 Ų112.4100%1.11363%0.631SS**  trans-108.80174.1-83.8-169.4176.6-172.5-0.4112.3

Retrieved 494 of 494 residues in 207.3 ms (Link to these results)