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Sphingomyelin synthase-related protein 1

Synthesizes sphingolipids through transfer of a phosphatidyl head group from a glycerophospholipid on to the primary hydroxyl of a ceramide in the lumen of the endoplasmic reticulum. Catalyzes the synthesis of ceramide phosphoethanolamines (CPEs) (such as N-acylsphing-4-enine 1-phosphoethanolamine) by transferring phosphoethanolamine head group, which is smaller and more hydrophilic than the phosphocholine (PC) headgroup transferred in the canonical sphingomyelin synthesis (SMS) reaction by SMS1 or SMS2, from a phosphatidylethanolamine (1,2-diacyl-sn-glycero-3-phosphoethanolamine, PE) to a ceramide (such as N-acylsphing-4-enine). The larger PC prevents an efficient fit in the enzyme's catalytic pocket, leading to little or no SMS activity. In vitro, in the absence of ceramide, it has PLC activity with preference for phosphatidylinositol and phosphatidic acid, but also hydrolyzes phosphatidylethanolamine.

AlphaFold DB , UniProt , Accession A0A060YED2, Species ONCMY (Oncorhynchus mykiss, Rainbow trout), Gene LOC110502814, Length 413 aa.

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	30.4	Very low	55.8	Low	247 Å²	247	118.3 Å²	118.3	100%	1.217	64%	0.644	S	S	*	*				0	126.5	0	-86.2	168.1	148	0	0	108.5
2	S	29	Very low	58.7	Low	110 Å²	110	112.1 Å²	112.1	77%	0.769	60%	0.604	S	S	*	*			trans	63.8	75.6	176.3	-178	0	0	0	0	118.1	S4	S2-S4 PolarHBondContact O-N 3.39Å; S2-S4 VanDerWaalsContact O-N 3.12Å
3	S	28.6	Very low	61.1	Low	121 Å²	121	108.8 Å²	108.8	85%	0.846	59%	0.591	S	S	*	*			trans	-69.2	91.5	154.8	50.5	0	0	0	0	109.5	T5	S3-T5 PolarHBondContact O-N 3.07Å
4	S	35.2	Very low	63.1	Low	92 Å²	92	104.1 Å²	104.1	64%	0.643	57%	0.567	S	S	*	*			trans	-73.4	104.3	170.5	45.8	0	0	0	0	109	S2 Q6	S2-S4 PolarHBondContact O-N 3.39Å; S2-S4 VanDerWaalsContact O-N 3.12Å; S4-Q6 PolarHBondContact O-N 3.09Å; S4-Q6 VanDerWaalsContact O-N 3.08Å
5	T	41.5	Very low	64.9	Low	130 Å²	130	108.6 Å²	108.6	80%	0.798	58%	0.579	S	S	*	*			trans	-45.7	110.5	161.7	4.9	0	0	0	0	108.7	S3 L7	S3-T5 PolarHBondContact O-N 3.07Å; T5-L7 PolarHBondContact O-N 3.38Å
6	Q	57	Low	66.5	Low	193 Å²	193	106.1 Å²	106.1	90%	0.902	56%	0.563	S	S	*	*			trans	-65.3	102.7	172.8	-84.2	-179.1	-15.7	0	0	107.9	S4	S4-Q6 PolarHBondContact O-N 3.09Å; S4-Q6 VanDerWaalsContact O-N 3.08Å
7	L	65.1	Low	67.9	Low	82 Å²	82	99.8 Å²	99.8	43%	0.429	53%	0.53	S	S	.	.			trans	-60.4	135.9	170.9	-83.2	125.7	0	0	0	109.4	T5 I9 Q11 W12	T5-L7 PolarHBondContact O-N 3.38Å; L7-I9 PolarHBondContact O-N 3.48Å; L7-Q11 HydrophobicContact CD2-CB 4.48Å; L7-W12 PolarHBondContact O-NE1 2.62Å
8	N	77.8	Confident	69.1	Low	84 Å²	84	95.1 Å²	95.1	45%	0.449	51%	0.507	S	S	.	.			trans	-56.2	136.6	175.3	-172.4	-46.2	0	0	0	109.8	R10 Q11 W12	N8-R10 PolarHBondContact O-N 3.28Å; N8-R10 VanDerWaalsContact O-N 3.09Å; N8-R10 PolarHBondContact OD1-N 3.44Å; N8-Q11 PolarHBondContact O-N 3.22Å; N8-W12 VanDerWaalsContact O-CD1 3.29Å
9	I	83	Confident	70.2	Confident	5 Å²	5	97.3 Å²	97.3	3%	0.026	51%	0.511	C	S	.	.	G	3₁₀ helix	trans	-54.7	-29.8	-177.7	-162	82.4	0	0	0	112.6	L7 Q11 W12 L45 L75 N79 I82	L7-I9 PolarHBondContact O-N 3.48Å; I9-Q11 PolarHBondContact O-N 2.85Å; I9-Q11 VanDerWaalsContact O-N 3.16Å; I9-W12 HydrophobicContact CD1-CD2 3.53Å; I9-W12 HydrophobicContact CD1-CE3 3.46Å; I9-W12 VanDerWaalsContact CD1-CE3 3.46Å; I9-W12 HydrophobicContact CD1-CG 4.18Å; I9-W12 HydrophobicContact CD1-CH2 3.75Å; I9-W12 HydrophobicContact CD1-CZ2 3.82Å; I9-W12 HydrophobicContact CD1-CZ3 3.58Å; I9-W12 HydrophobicContact CG1-CD2 4.43Å; I9-W12 WeakPolarHBondContact O-CB 3.25Å; I9-W12 PolarHBondContact O-N 3.36Å; I9-W12 VanDerWaalsContact O-N 3.08Å; I9-L45 HydrophobicContact CB-CD1 4.27Å; I9-L45 HydrophobicContact CG1-CD1 3.66Å; I9-L45 HydrophobicContact CG1-CD2 4.41Å; I9-L45 HydrophobicContact CG1-CG 3.93Å; I9-L45 HydrophobicContact CG2-CD1 3.6Å; I9-L75 HydrophobicContact CD1-CD1 4.02Å; I9-L75 HydrophobicContact CD1-CD2 3.95Å; I9-L75 HydrophobicContact CD1-CG 4.16Å; I9-N79 HydrophobicContact CG2-CB 4.28Å; I9-N79 VanDerWaalsContact CG2-OD1 3.3Å; I9-N79 WeakPolarHBondContact CG2-OD1 3.3Å; I9-I82 HydrophobicContact CG2-CD1 3.29Å
10	R	81.4	Confident	71.4	Confident	111 Å²	111	93.8 Å²	93.8	42%	0.419	49%	0.491	S	S	.	.	G	3₁₀ helix	trans	-60.4	-24.8	175.6	-63.7	-168.9	-175	-154.8	3	113.3	N8 M42 I82 E85	N8-R10 PolarHBondContact O-N 3.28Å; N8-R10 VanDerWaalsContact O-N 3.09Å; N8-R10 PolarHBondContact OD1-N 3.44Å; R10-M42 HydrophobicContact CB-SD 4.33Å; R10-M42 HydrophobicContact CG-SD 3.92Å; R10-I82 HydrophobicContact CG-CD1 3.96Å; R10-I82 HydrophobicContact CG-CG2 4.42Å; R10-E85 IonicContact CZ-OE1 2.68Å; R10-E85 IonicContact CZ-OE2 3.64Å; R10-E85 IonicContact NH1-OE1 2.66Å; R10-E85 PolarHBondContact NH1-OE1 3.12Å; R10-E85 IonicContact NH1-OE2 2.94Å; R10-E85 PolarHBondContact NH1-OE2 3.19Å; R10-E85 VanDerWaalsContact NH2-CD 3.26Å; R10-E85 IonicContact NH2-OE1 3.53Å; R10-E85 PolarHBondContact NH2-OE1 3.08Å; R10-E85 IonicContact NH2-OE2 3.43Å; R10-E85 PolarHBondContact NH2-OE2 2.91Å
11	Q	85.1	Confident	72.3	Confident	126 Å²	126	89.3 Å²	89.3	59%	0.589	47%	0.468	S	S	*	.	G	3₁₀ helix	trans	-97.8	1.7	-178.4	-63.1	177.9	-20.3	0	0	112.5	L7 N8 I9 T13	L7-Q11 HydrophobicContact CD2-CB 4.48Å; N8-Q11 PolarHBondContact O-N 3.22Å; I9-Q11 PolarHBondContact O-N 2.85Å; I9-Q11 VanDerWaalsContact O-N 3.16Å; Q11-T13 PolarHBondContact O-N 3.07Å; Q11-T13 VanDerWaalsContact O-N 3.14Å
12	W	90.2	Very high	75.2	Confident	44 Å²	44	83.2 Å²	83.2	17%	0.167	43%	0.434	C	S	.	.			trans	-72.9	110.9	-179	-77.2	27.7	0	0	0	111.1	L7 N8 I9 H16 V17 W20 G41 L44 L75	L7-W12 PolarHBondContact O-NE1 2.62Å; N8-W12 VanDerWaalsContact O-CD1 3.29Å; I9-W12 HydrophobicContact CD1-CD2 3.53Å; I9-W12 HydrophobicContact CD1-CE3 3.46Å; I9-W12 VanDerWaalsContact CD1-CE3 3.46Å; I9-W12 HydrophobicContact CD1-CG 4.18Å; I9-W12 HydrophobicContact CD1-CH2 3.75Å; I9-W12 HydrophobicContact CD1-CZ2 3.82Å; I9-W12 HydrophobicContact CD1-CZ3 3.58Å; I9-W12 HydrophobicContact CG1-CD2 4.43Å; I9-W12 WeakPolarHBondContact O-CB 3.25Å; I9-W12 PolarHBondContact O-N 3.36Å; I9-W12 VanDerWaalsContact O-N 3.08Å; W12-H16 HydrophobicContact CB-CB 3.92Å; W12-H16 HydrophobicContact CD2-CB 4.15Å; W12-H16 HydrophobicContact CG-CB 3.87Å; W12-V17 HydrophobicContact CE3-CG2 4.25Å; W12-W20 HydrophobicContact CH2-CB 4.01Å; W12-W20 AromaticContact CH2-CD1 3.6Å; W12-W20 AromaticContact CH2-CG 3.83Å; W12-W20 HydrophobicContact CH2-CG 3.83Å; W12-W20 HydrophobicContact CZ3-CB 3.67Å; W12-W20 AromaticContact CZ3-CD1 3.9Å; W12-W20 HydrophobicContact CZ3-CD2 4.31Å; W12-W20 AromaticContact CZ3-CG 3.65Å; W12-W20 HydrophobicContact CZ3-CG 3.65Å; W12-G41 PolarHBondContact O-N 3.06Å; W12-L44 HydrophobicContact CZ3-CD2 4.41Å; W12-L75 HydrophobicContact CH2-CD1 4.22Å; W12-L75 HydrophobicContact CZ3-CD2 4.42Å
13	T	89.7	Confident	78.1	Confident	69 Å²	69	83.8 Å²	83.8	42%	0.423	43%	0.429	S	S	.	.			trans	-77.8	170.8	167.6	66.9	0	0	0	0	111.4	Q11 K15 H16 V17	Q11-T13 PolarHBondContact O-N 3.07Å; Q11-T13 VanDerWaalsContact O-N 3.14Å; T13-K15 PolarHBondContact O-N 3.47Å; T13-H16 PolarHBondContact N-ND1 2.98Å; T13-H16 WeakPolarHBondContact O-CA 3.32Å; T13-H16 WeakPolarHBondContact O-CB 3.47Å; T13-H16 PolarHBondContact O-N 3.19Å; T13-H16 PolarHBondContact OG1-ND1 3.16Å; T13-V17 PolarHBondContact O-N 3.28Å; T13-V17 VanDerWaalsContact O-N 3.1Å
14	T	89.5	Confident	81	Confident	43 Å²	43	81.3 Å²	81.3	26%	0.264	40%	0.404	S	S	.	.	H	α-helix	trans	-52.7	-29.9	176.1	59.1	0	0	0	0	113.5	A18 R38	T14-A18 VanDerWaalsContact O-CB 3.29Å; T14-A18 WeakPolarHBondContact O-CB 3.4Å; T14-A18 PolarHBondContact O-N 3.06Å; T14-R38 HydrophobicContact CG2-CB 4.23Å
15	K	89.9	Confident	83.5	Confident	172 Å²	172	79.7 Å²	79.7	75%	0.748	40%	0.401	S	S	*	.	H	α-helix	trans	-69.1	-35.1	175.1	-64.9	-175.6	-179.6	179.2	0	112.8	T13 K19	T13-K15 PolarHBondContact O-N 3.47Å; K15-K19 PolarHBondContact O-N 3.11Å; K15-K19 VanDerWaalsContact O-N 3.12Å
16	H	90.2	Very high	85.9	Confident	68 Å²	68	74.1 Å²	74.1	32%	0.315	37%	0.366	S	S	.	.	H	α-helix	trans	-73.6	-42.1	176.7	-62.7	91.1	0	0	0	110.7	W12 T13 A18 K19 W20	W12-H16 HydrophobicContact CB-CB 3.92Å; W12-H16 HydrophobicContact CD2-CB 4.15Å; W12-H16 HydrophobicContact CG-CB 3.87Å; T13-H16 PolarHBondContact N-ND1 2.98Å; T13-H16 WeakPolarHBondContact O-CA 3.32Å; T13-H16 WeakPolarHBondContact O-CB 3.47Å; T13-H16 PolarHBondContact O-N 3.19Å; T13-H16 PolarHBondContact OG1-ND1 3.16Å; H16-A18 VanDerWaalsContact C-N 3.32Å; H16-A18 PolarHBondContact O-N 3.39Å; H16-K19 PolarHBondContact O-N 3.28Å; H16-W20 PolarHBondContact O-N 3.26Å
17	V	90	Very high	87.4	Confident	0 Å²	0	68.3 Å²	68.3	0%	0	35%	0.346	C	S	.	.	H	α-helix	trans	-60.5	-42.2	172.1	177.8	0	0	0	0	111	W12 T13 K19 W20 L21 L44	W12-V17 HydrophobicContact CE3-CG2 4.25Å; T13-V17 PolarHBondContact O-N 3.28Å; T13-V17 VanDerWaalsContact O-N 3.1Å; V17-K19 VanDerWaalsContact C-N 3.3Å; V17-K19 PolarHBondContact O-N 3.45Å; V17-W20 PolarHBondContact O-N 3.13Å; V17-L21 HydrophobicContact CG1-CD1 4.09Å; V17-L21 HydrophobicContact CG1-CG 4.35Å; V17-L21 WeakPolarHBondContact O-CB 3.31Å; V17-L21 WeakPolarHBondContact O-CG 3.47Å; V17-L21 PolarHBondContact O-N 3.47Å; V17-L44 HydrophobicContact CG1-CD1 4.12Å; V17-L44 HydrophobicContact CG1-CD2 4.05Å; V17-L44 HydrophobicContact CG2-CD2 4.3Å
18	A	89.8	Confident	88.5	Confident	14 Å²	14	72.8 Å²	72.8	12%	0.116	37%	0.365	C	S	.	.	H	α-helix	trans	-62	-37.1	176.3	0	0	0	0	0	112.7	T14 H16 K22 V30 C34	T14-A18 VanDerWaalsContact O-CB 3.29Å; T14-A18 WeakPolarHBondContact O-CB 3.4Å; T14-A18 PolarHBondContact O-N 3.06Å; H16-A18 VanDerWaalsContact C-N 3.32Å; H16-A18 PolarHBondContact O-N 3.39Å; A18-K22 VanDerWaalsContact O-CG 3.31Å; A18-K22 WeakPolarHBondContact O-CG 3.29Å; A18-K22 PolarHBondContact O-N 3.49Å; A18-V30 HydrophobicContact CB-CG1 3.62Å; A18-C34 HydrophobicContact CB-CB 4.17Å; A18-C34 PolarHBondContact N-SG 2.78Å
19	K	91.4	Very high	89.1	Confident	137 Å²	137	70.5 Å²	70.5	60%	0.596	35%	0.35	S	S	*	.	H	α-helix	trans	-67.9	-47.5	174.8	-173.4	177.6	177.6	-179	0	110.9	K15 H16 V17 L21 K22 D23	K15-K19 PolarHBondContact O-N 3.11Å; K15-K19 VanDerWaalsContact O-N 3.12Å; H16-K19 PolarHBondContact O-N 3.28Å; V17-K19 VanDerWaalsContact C-N 3.3Å; V17-K19 PolarHBondContact O-N 3.45Å; K19-L21 PolarHBondContact O-N 2.86Å; K19-K22 WeakPolarHBondContact O-CB 3.36Å; K19-K22 PolarHBondContact O-N 3.17Å; K19-K22 VanDerWaalsContact O-N 3.13Å; K19-D23 VanDerWaalsContact O-CG 3.32Å; K19-D23 PolarHBondContact O-N 3.49Å
20	W	93.1	Very high	89.4	Confident	28 Å²	28	71 Å²	71	11%	0.106	35%	0.353	C	S	.	.	H	α-helix	trans	-59.4	-43.6	177.1	178.8	82	0	0	0	112.6	W12 H16 V17 K22 D23 E24 L44 L68 L72 L75	W12-W20 HydrophobicContact CH2-CB 4.01Å; W12-W20 AromaticContact CH2-CD1 3.6Å; W12-W20 AromaticContact CH2-CG 3.83Å; W12-W20 HydrophobicContact CH2-CG 3.83Å; W12-W20 HydrophobicContact CZ3-CB 3.67Å; W12-W20 AromaticContact CZ3-CD1 3.9Å; W12-W20 HydrophobicContact CZ3-CD2 4.31Å; W12-W20 AromaticContact CZ3-CG 3.65Å; W12-W20 HydrophobicContact CZ3-CG 3.65Å; H16-W20 PolarHBondContact O-N 3.26Å; V17-W20 PolarHBondContact O-N 3.13Å; W20-K22 VanDerWaalsContact C-N 3.29Å; W20-K22 PolarHBondContact O-N 3.14Å; W20-D23 PolarHBondContact O-N 3.36Å; W20-E24 HydrophobicContact CD2-CG 4.15Å; W20-E24 HydrophobicContact CH2-CG 4.36Å; W20-E24 HydrophobicContact CZ2-CG 3.82Å; W20-E24 PolarHBondContact O-N 3.16Å; W20-L44 HydrophobicContact CD2-CD2 4.35Å; W20-L44 HydrophobicContact CE3-CD2 3.81Å; W20-L44 HydrophobicContact CZ3-CD1 4.2Å; W20-L44 HydrophobicContact CZ3-CD2 3.91Å; W20-L68 HydrophobicContact CZ3-CD1 4.34Å; W20-L72 HydrophobicContact CH2-CD2 4.08Å; W20-L72 HydrophobicContact CH2-CG 4.46Å; W20-L72 HydrophobicContact CZ3-CD2 4.38Å; W20-L75 HydrophobicContact CH2-CD2 4.46Å; W20-L75 HydrophobicContact CZ2-CB 4.31Å; W20-L75 HydrophobicContact CZ2-CD2 4.05Å
21	L	90.9	Very high	89.7	Confident	0 Å²	0	70.7 Å²	70.7	0%	0	36%	0.36	C	S	.	.	H	α-helix	trans	-60.8	-36.9	175.7	-77	171.7	0	0	0	112.3	V17 K19 G25 F26 V30 L33 L68	V17-L21 HydrophobicContact CG1-CD1 4.09Å; V17-L21 HydrophobicContact CG1-CG 4.35Å; V17-L21 WeakPolarHBondContact O-CB 3.31Å; V17-L21 WeakPolarHBondContact O-CG 3.47Å; V17-L21 PolarHBondContact O-N 3.47Å; K19-L21 PolarHBondContact O-N 2.86Å; L21-G25 PolarHBondContact O-N 3.19Å; L21-F26 HydrophobicContact CB-CB 4.46Å; L21-F26 HydrophobicContact CD2-CB 4.06Å; L21-F26 WeakPolarHBondContact O-CA 3.23Å; L21-F26 PolarHBondContact O-N 3.43Å; L21-V30 HydrophobicContact CB-CG2 3.95Å; L21-V30 HydrophobicContact CD1-CG2 4.42Å; L21-L33 HydrophobicContact CD1-CB 4.02Å; L21-L33 HydrophobicContact CD1-CD1 3.83Å; L21-L33 HydrophobicContact CD2-CD1 4.09Å; L21-L68 HydrophobicContact CD2-CD1 3.88Å
22	K	90.9	Very high	90	Very high	118 Å²	118	66.6 Å²	66.6	51%	0.513	34%	0.342	S	S	.	.	H	α-helix	trans	-68.2	-42.4	175.3	-71.3	174.8	-177.5	-175.5	0	111.6	A18 K19 W20 E24 G25 V30	A18-K22 VanDerWaalsContact O-CG 3.31Å; A18-K22 WeakPolarHBondContact O-CG 3.29Å; A18-K22 PolarHBondContact O-N 3.49Å; K19-K22 WeakPolarHBondContact O-CB 3.36Å; K19-K22 PolarHBondContact O-N 3.17Å; K19-K22 VanDerWaalsContact O-N 3.13Å; W20-K22 VanDerWaalsContact C-N 3.29Å; W20-K22 PolarHBondContact O-N 3.14Å; K22-E24 VanDerWaalsContact C-N 3.3Å; K22-E24 PolarHBondContact O-N 3.35Å; K22-G25 PolarHBondContact O-N 3Å; K22-G25 VanDerWaalsContact O-N 3.11Å; K22-V30 HydrophobicContact CG-CG2 4.01Å
23	D	90.3	Very high	89.9	Confident	122 Å²	122	64.6 Å²	64.6	65%	0.652	33%	0.334	S	S	*	.	H	α-helix	trans	-65.7	-33.6	179.8	-64.9	-18.6	0	0	0	111.8	K19 W20 G25	K19-D23 VanDerWaalsContact O-CG 3.32Å; K19-D23 PolarHBondContact O-N 3.49Å; W20-D23 PolarHBondContact O-N 3.36Å; D23-G25 VanDerWaalsContact C-N 3.31Å
24	E	89.1	Confident	89.9	Confident	69 Å²	69	61.5 Å²	61.5	32%	0.322	32%	0.315	S	S	.	.	T	Hydrogen-bonded Turn	trans	-83.7	-0.6	174.9	-67.7	-72.5	141.8	0	0	113.8	W20 K22 F26 S71	W20-E24 HydrophobicContact CD2-CG 4.15Å; W20-E24 HydrophobicContact CH2-CG 4.36Å; W20-E24 HydrophobicContact CZ2-CG 3.82Å; W20-E24 PolarHBondContact O-N 3.16Å; K22-E24 VanDerWaalsContact C-N 3.3Å; K22-E24 PolarHBondContact O-N 3.35Å; E24-F26 HydrophobicContact CB-CD2 3.84Å; E24-F26 HydrophobicContact CB-CE2 4Å; E24-F26 WeakPolarHBondContact O-CE2 3.43Å; E24-S71 VanDerWaalsContact OE2-CB 3.25Å; E24-S71 WeakPolarHBondContact OE2-CB 3.46Å; E24-S71 PolarHBondContact OE2-OG 2.96Å
25	G	88.8	Confident	89.7	Confident	58 Å²	58	64.6 Å²	64.6	60%	0.598	33%	0.33	S	S	*	.	T	Hydrogen-bonded Turn	trans	89.6	14.2	174.3	0	0	0	0	0	116.2	L21 K22 D23	L21-G25 PolarHBondContact O-N 3.19Å; K22-G25 PolarHBondContact O-N 3Å; K22-G25 VanDerWaalsContact O-N 3.11Å; D23-G25 VanDerWaalsContact C-N 3.31Å
26	F	90.7	Very high	89.6	Confident	14 Å²	14	63.2 Å²	63.2	6%	0.061	32%	0.324	C	S	.	.			trans	-101.9	40.7	-179.3	-60.5	-76.3	0	0	0	113.3	L21 E24 H28 Y29 R67 L68	L21-F26 HydrophobicContact CB-CB 4.46Å; L21-F26 HydrophobicContact CD2-CB 4.06Å; L21-F26 WeakPolarHBondContact O-CA 3.23Å; L21-F26 PolarHBondContact O-N 3.43Å; E24-F26 HydrophobicContact CB-CD2 3.84Å; E24-F26 HydrophobicContact CB-CE2 4Å; E24-F26 WeakPolarHBondContact O-CE2 3.43Å; F26-H28 VanDerWaalsContact C-N 3.26Å; F26-H28 PolarHBondContact O-N 2.93Å; F26-Y29 HydrophobicContact CB-CD2 4.21Å; F26-Y29 HydrophobicContact CD1-CD2 4.06Å; F26-Y29 HydrophobicContact CD1-CE2 4.39Å; F26-Y29 PolarHBondContact O-N 3.38Å; F26-R67 HydrophobicContact CE1-CB 4.06Å; F26-R67 HydrophobicContact CZ-CB 3.68Å; F26-L68 HydrophobicContact CD1-CB 4.41Å; F26-L68 HydrophobicContact CD2-CD1 3.87Å; F26-L68 HydrophobicContact CE1-CB 3.89Å; F26-L68 HydrophobicContact CE2-CB 4.28Å; F26-L68 HydrophobicContact CE2-CD1 3.95Å; F26-L68 HydrophobicContact CG-CD1 4.19Å; F26-L68 VanDerWaalsContact CZ-CA 3.47Å; F26-L68 HydrophobicContact CZ-CB 3.83Å; F26-L68 HydrophobicContact CZ-CD1 4.34Å; F26-L68 VanDerWaalsContact CZ-N 3.26Å
27	C	88.8	Confident	89.5	Confident	71 Å²	71	62.5 Å²	62.5	48%	0.48	32%	0.321	S	S	.	.	G	3₁₀ helix	trans	-54.1	-37.6	-176.6	-64.2	0	0	0	0	114	Y29 V30	C27-Y29 VanDerWaalsContact C-N 3.25Å; C27-Y29 PolarHBondContact O-N 2.86Å; C27-V30 WeakPolarHBondContact O-CG2 3.32Å; C27-V30 PolarHBondContact O-N 3.27Å
28	H	88.4	Confident	89.5	Confident	176 Å²	176	71.6 Å²	71.6	82%	0.815	36%	0.355	S	S	*	.	G	3₁₀ helix	trans	-68.2	-22.8	-178.8	-65.5	-72.9	0	0	0	113.6	F26	F26-H28 VanDerWaalsContact C-N 3.26Å; F26-H28 PolarHBondContact O-N 2.93Å
29	Y	89.3	Confident	89.4	Confident	35 Å²	35	71.9 Å²	71.9	14%	0.137	36%	0.355	C	S	.	.	G	3₁₀ helix	trans	-93.2	-4.1	-178.7	-64.4	-63.3	0	0	0	113.5	F26 C27 D31 L32 L33 L59 D64	F26-Y29 HydrophobicContact CB-CD2 4.21Å; F26-Y29 HydrophobicContact CD1-CD2 4.06Å; F26-Y29 HydrophobicContact CD1-CE2 4.39Å; F26-Y29 PolarHBondContact O-N 3.38Å; C27-Y29 VanDerWaalsContact C-N 3.25Å; C27-Y29 PolarHBondContact O-N 2.86Å; Y29-D31 PolarHBondContact O-N 3.18Å; Y29-L32 HydrophobicContact CD1-CD2 4.35Å; Y29-L32 PolarHBondContact O-N 2.96Å; Y29-L33 VanDerWaalsContact O-CB 3.25Å; Y29-L33 WeakPolarHBondContact O-CB 3.34Å; Y29-L33 WeakPolarHBondContact O-CG 3.41Å; Y29-L33 PolarHBondContact O-N 3.12Å; Y29-L59 HydrophobicContact CD1-CD2 3.54Å; Y29-L59 HydrophobicContact CE1-CD2 3.3Å; Y29-D64 HydrophobicContact CE2-CB 3.76Å; Y29-D64 PolarHBondContact OH-OD2 3.28Å; Y29-D64 VanDerWaalsContact OH-OD2 3.07Å
30	V	90.1	Very high	89.4	Confident	15 Å²	15	68.3 Å²	68.3	9%	0.091	34%	0.342	C	S	.	.	H	α-helix	trans	-61.4	-43	180	174.4	0	0	0	0	111.6	A18 L21 K22 C27 C34 N35	A18-V30 HydrophobicContact CB-CG1 3.62Å; L21-V30 HydrophobicContact CB-CG2 3.95Å; L21-V30 HydrophobicContact CD1-CG2 4.42Å; K22-V30 HydrophobicContact CG-CG2 4.01Å; C27-V30 WeakPolarHBondContact O-CG2 3.32Å; C27-V30 PolarHBondContact O-N 3.27Å; V30-C34 HydrophobicContact CG1-CB 4.41Å; V30-C34 WeakPolarHBondContact O-CA 3.3Å; V30-C34 WeakPolarHBondContact O-CB 3.5Å; V30-C34 PolarHBondContact O-N 3.04Å; V30-N35 PolarHBondContact O-N 3.2Å
31	D	88.6	Confident	89.1	Confident	105 Å²	105	67 Å²	67	56%	0.561	34%	0.337	S	S	*	.	I	π-helix	trans	-65.9	-43.5	-179.5	-168	56.8	0	0	0	111.5	Y29 N35 K36	Y29-D31 PolarHBondContact O-N 3.18Å; D31-N35 CarbonylContact O-C 3.6Å; D31-N35 WeakPolarHBondContact O-CA 3.26Å; D31-N35 VanDerWaalsContact O-CB 3.26Å; D31-N35 WeakPolarHBondContact O-CB 3.38Å; D31-N35 PolarHBondContact O-N 3.03Å; D31-N35 VanDerWaalsContact O-N 3.11Å; D31-N35 WeakPolarHBondContact OD1-CB 3.28Å; D31-N35 PolarHBondContact OD1-ND2 3.31Å; D31-K36 PolarHBondContact O-N 3.37Å
32	L	89.6	Confident	88.9	Confident	41 Å²	41	69.2 Å²	69.2	22%	0.215	35%	0.348	C	S	.	.	I	π-helix	trans	-64.3	-56.5	176.7	-174.7	68	0	0	0	111.6	Y29 K36 H37 L59	Y29-L32 HydrophobicContact CD1-CD2 4.35Å; Y29-L32 PolarHBondContact O-N 2.96Å; L32-K36 HydrophobicContact CD1-CD 3.96Å; L32-K36 WeakPolarHBondContact O-CB 3.44Å; L32-H37 PolarHBondContact O-CD2 3.01Å; L32-H37 PolarHBondContact O-N 3.5Å; L32-L59 HydrophobicContact CD2-CD2 3.72Å
33	L	89.2	Confident	88.7	Confident	2 Å²	2	65.8 Å²	65.8	1%	0.01	34%	0.339	C	S	.	.	I	π-helix	trans	-74.1	-41.6	-171.4	-67.6	176.7	0	0	0	112.7	L21 Y29 H37 R38 L39 L57 L68	L21-L33 HydrophobicContact CD1-CB 4.02Å; L21-L33 HydrophobicContact CD1-CD1 3.83Å; L21-L33 HydrophobicContact CD2-CD1 4.09Å; Y29-L33 VanDerWaalsContact O-CB 3.25Å; Y29-L33 WeakPolarHBondContact O-CB 3.34Å; Y29-L33 WeakPolarHBondContact O-CG 3.41Å; Y29-L33 PolarHBondContact O-N 3.12Å; L33-H37 CarbonylContact O-C 3.59Å; L33-R38 PolarHBondContact O-N 2.84Å; L33-L39 HydrophobicContact CB-CD1 3.93Å; L33-L39 HydrophobicContact CD2-CD1 3.58Å; L33-L39 HydrophobicContact CG-CD1 4.26Å; L33-L39 WeakPolarHBondContact O-CB 3.31Å; L33-L39 WeakPolarHBondContact O-CG 3.29Å; L33-L39 PolarHBondContact O-N 3.01Å; L33-L57 HydrophobicContact CD2-CD1 3.82Å; L33-L57 HydrophobicContact CD2-CD2 3.68Å; L33-L57 HydrophobicContact CD2-CG 4.39Å; L33-L68 HydrophobicContact CD1-CD2 4.26Å
34	C	89.3	Confident	88.7	Confident	3 Å²	3	60.1 Å²	60.1	2%	0.02	31%	0.309	C	S	.	.	I	π-helix	trans	-98.7	-39.2	-173.8	-60.9	0	0	0	0	113.7	A18 V30 R38	A18-C34 HydrophobicContact CB-CB 4.17Å; A18-C34 PolarHBondContact N-SG 2.78Å; V30-C34 HydrophobicContact CG1-CB 4.41Å; V30-C34 WeakPolarHBondContact O-CA 3.3Å; V30-C34 WeakPolarHBondContact O-CB 3.5Å; V30-C34 PolarHBondContact O-N 3.04Å; C34-R38 VanDerWaalsContact O-CA 3.31Å; C34-R38 WeakPolarHBondContact O-CA 3.43Å; C34-R38 PolarHBondContact O-N 3.33Å
35	N	85.6	Confident	88.6	Confident	108 Å²	108	57 Å²	57	58%	0.578	29%	0.294	S	S	*	.	I	π-helix	trans	-87.5	-43.8	-176.8	-61	-26.3	0	0	0	111.7	V30 D31	V30-N35 PolarHBondContact O-N 3.2Å; D31-N35 CarbonylContact O-C 3.6Å; D31-N35 WeakPolarHBondContact O-CA 3.26Å; D31-N35 VanDerWaalsContact O-CB 3.26Å; D31-N35 WeakPolarHBondContact O-CB 3.38Å; D31-N35 PolarHBondContact O-N 3.03Å; D31-N35 VanDerWaalsContact O-N 3.11Å; D31-N35 WeakPolarHBondContact OD1-CB 3.28Å; D31-N35 PolarHBondContact OD1-ND2 3.31Å
36	K	86.9	Confident	88.5	Confident	144 Å²	144	57.1 Å²	57.1	63%	0.626	28%	0.284	S	S	*	.	I	π-helix	trans	-83.3	-48.7	-179.6	-168.5	-175.9	-178.9	-170.7	0	112.8	D31 L32	D31-K36 PolarHBondContact O-N 3.37Å; L32-K36 HydrophobicContact CD1-CD 3.96Å; L32-K36 WeakPolarHBondContact O-CB 3.44Å
37	H	88.9	Confident	88.3	Confident	52 Å²	52	57 Å²	57	24%	0.241	28%	0.284	C	S	.	.	S	Bend	trans	-99.1	-2.6	-176	-66.3	-67.8	0	0	0	114.8	L32 L33 L39 P56 L57	L32-H37 PolarHBondContact O-CD2 3.01Å; L32-H37 PolarHBondContact O-N 3.5Å; L33-H37 CarbonylContact O-C 3.59Å; H37-L39 VanDerWaalsContact C-N 3.27Å; H37-L39 PolarHBondContact O-N 2.85Å; H37-P56 PolarHBondContact CE1-O 2.87Å; H37-P56 PolarHBondContact NE2-O 3.37Å; H37-L57 HydrophobicContact CB-CD2 4.07Å; H37-L57 WeakPolarHBondContact CD2-CD2 3.44Å
38	R	89.7	Confident	88.1	Confident	191 Å²	191	55.7 Å²	55.7	72%	0.721	28%	0.275	S	S	*	.			trans	51.3	39.9	172.2	-59.9	-175.2	64.4	-159.4	-3	114.4	T14 L33 C34 D40	T14-R38 HydrophobicContact CG2-CB 4.23Å; L33-R38 PolarHBondContact O-N 2.84Å; C34-R38 VanDerWaalsContact O-CA 3.31Å; C34-R38 WeakPolarHBondContact O-CA 3.43Å; C34-R38 PolarHBondContact O-N 3.33Å; R38-D40 PolarHBondContact O-N 3.1Å
39	L	88.8	Confident	87.9	Confident	20 Å²	20	49.3 Å²	49.3	11%	0.105	25%	0.246	C	C	.	.			trans	-64.8	121.7	177.5	-66.9	175.5	0	0	0	111.5	L33 H37 L47	L33-L39 HydrophobicContact CB-CD1 3.93Å; L33-L39 HydrophobicContact CD2-CD1 3.58Å; L33-L39 HydrophobicContact CG-CD1 4.26Å; L33-L39 WeakPolarHBondContact O-CB 3.31Å; L33-L39 WeakPolarHBondContact O-CG 3.29Å; L33-L39 PolarHBondContact O-N 3.01Å; H37-L39 VanDerWaalsContact C-N 3.27Å; H37-L39 PolarHBondContact O-N 2.85Å; L39-L47 HydrophobicContact CD1-CD1 3.67Å; L39-L47 HydrophobicContact CD2-CD1 4.01Å
40	D	89.7	Confident	87.6	Confident	62 Å²	62	55.6 Å²	55.6	33%	0.332	27%	0.27	S	S	.	.			trans	-98.1	176.6	170.5	66.2	-0.9	0	0	0	110.8	R38 M42 S43 L44	R38-D40 PolarHBondContact O-N 3.1Å; D40-M42 VanDerWaalsContact C-N 3.26Å; D40-M42 PolarHBondContact O-N 2.85Å; D40-S43 PolarHBondContact O-N 3.47Å; D40-S43 WeakPolarHBondContact OD1-CB 3.33Å; D40-S43 PolarHBondContact OD1-N 3.01Å; D40-S43 PolarHBondContact OD1-OG 3Å; D40-L44 WeakPolarHBondContact O-CB 3.43Å; D40-L44 PolarHBondContact O-N 3.24Å
41	G	87	Confident	87.5	Confident	0 Å²	0	58 Å²	58	0%	0	28%	0.283	C	S	.	.	H	α-helix	trans	-58.8	-35.8	-175.4	0	0	0	0	0	114.4	W12 L45	W12-G41 PolarHBondContact O-N 3.06Å; G41-L45 WeakPolarHBondContact O-CG 3.28Å; G41-L45 PolarHBondContact O-N 2.81Å; G41-L45 VanDerWaalsContact O-N 3.1Å
42	M	86.2	Confident	87.4	Confident	48 Å²	48	53 Å²	53	24%	0.236	26%	0.256	C	S	.	.	H	α-helix	trans	-71.8	-46	179.5	-62.4	-56.2	-65.9	0	0	111	R10 D40 L44 L45 T46 I82 L86	R10-M42 HydrophobicContact CB-SD 4.33Å; R10-M42 HydrophobicContact CG-SD 3.92Å; D40-M42 VanDerWaalsContact C-N 3.26Å; D40-M42 PolarHBondContact O-N 2.85Å; M42-L44 VanDerWaalsContact C-N 3.27Å; M42-L44 PolarHBondContact O-N 3.31Å; M42-L45 PolarHBondContact O-N 3.11Å; M42-L45 VanDerWaalsContact O-N 3.17Å; M42-T46 PolarHBondContact O-N 3.38Å; M42-T46 PolarHBondContact O-OG1 2.91Å; M42-I82 HydrophobicContact CE-CG2 3.79Å; M42-I82 HydrophobicContact SD-CG2 4.19Å; M42-L86 HydrophobicContact CE-CD1 3.51Å; M42-L86 HydrophobicContact CE-CD2 4.07Å; M42-L86 HydrophobicContact CE-CG 4.23Å
43	S	87.8	Confident	87.3	Confident	46 Å²	46	57 Å²	57	32%	0.322	27%	0.268	S	S	.	.	H	α-helix	trans	-64	-34.5	176.5	-54.7	0	0	0	0	112	D40 T46 L47	D40-S43 PolarHBondContact O-N 3.47Å; D40-S43 WeakPolarHBondContact OD1-CB 3.33Å; D40-S43 PolarHBondContact OD1-N 3.01Å; D40-S43 PolarHBondContact OD1-OG 3Å; S43-T46 PolarHBondContact O-OG1 2.84Å; S43-L47 PolarHBondContact O-N 3.31Å
44	L	89.6	Confident	86.9	Confident	3 Å²	3	57.8 Å²	57.8	2%	0.016	27%	0.274	C	S	.	.	H	α-helix	trans	-65.1	-40.9	174.5	-171.9	74.1	0	0	0	111.6	W12 V17 W20 D40 M42 T46 L47 L72 L75	W12-L44 HydrophobicContact CZ3-CD2 4.41Å; V17-L44 HydrophobicContact CG1-CD1 4.12Å; V17-L44 HydrophobicContact CG1-CD2 4.05Å; V17-L44 HydrophobicContact CG2-CD2 4.3Å; W20-L44 HydrophobicContact CD2-CD2 4.35Å; W20-L44 HydrophobicContact CE3-CD2 3.81Å; W20-L44 HydrophobicContact CZ3-CD1 4.2Å; W20-L44 HydrophobicContact CZ3-CD2 3.91Å; D40-L44 WeakPolarHBondContact O-CB 3.43Å; D40-L44 PolarHBondContact O-N 3.24Å; M42-L44 VanDerWaalsContact C-N 3.27Å; M42-L44 PolarHBondContact O-N 3.31Å; L44-T46 VanDerWaalsContact C-N 3.35Å; L44-L47 VanDerWaalsContact O-CB 3.3Å; L44-L47 WeakPolarHBondContact O-CB 3.29Å; L44-L47 PolarHBondContact O-N 2.83Å; L44-L72 HydrophobicContact CD1-CD2 3.58Å; L44-L72 HydrophobicContact CD2-CD2 4.47Å; L44-L72 HydrophobicContact CG-CD2 3.64Å; L44-L72 WeakPolarHBondContact O-CD2 3.24Å; L44-L75 HydrophobicContact CD2-CD2 3.58Å; L44-L75 HydrophobicContact CG-CD2 4.27Å
45	L	87	Confident	86.5	Confident	2 Å²	2	62.2 Å²	62.2	1%	0.01	30%	0.303	C	S	.	.	H	α-helix	trans	-67.1	-33.7	178.6	-79.8	175.5	0	0	0	113.1	I9 G41 M42 L47 L75 Q76 N79 I82	I9-L45 HydrophobicContact CB-CD1 4.27Å; I9-L45 HydrophobicContact CG1-CD1 3.66Å; I9-L45 HydrophobicContact CG1-CD2 4.41Å; I9-L45 HydrophobicContact CG1-CG 3.93Å; I9-L45 HydrophobicContact CG2-CD1 3.6Å; G41-L45 WeakPolarHBondContact O-CG 3.28Å; G41-L45 PolarHBondContact O-N 2.81Å; G41-L45 VanDerWaalsContact O-N 3.1Å; M42-L45 PolarHBondContact O-N 3.11Å; M42-L45 VanDerWaalsContact O-N 3.17Å; L45-L47 VanDerWaalsContact C-N 3.29Å; L45-L75 HydrophobicContact CD2-CD2 4.34Å; L45-L75 HydrophobicContact CD2-CG 4.06Å; L45-Q76 HydrophobicContact CD2-CG 4.22Å; L45-Q76 WeakPolarHBondContact O-CG 3.2Å; L45-Q76 PolarHBondContact O-NE2 2.7Å; L45-N79 HydrophobicContact CD1-CB 4.26Å; L45-N79 HydrophobicContact CD2-CB 4.17Å; L45-I82 HydrophobicContact CD1-CG2 4.32Å
46	T	86.3	Confident	86.3	Confident	62 Å²	62	61.3 Å²	61.3	38%	0.38	30%	0.303	S	S	.	.	T	Hydrogen-bonded Turn	trans	-86.9	-0.8	179.9	56.4	0	0	0	0	113.3	M42 S43 L44 S48 L86 V88	M42-T46 PolarHBondContact O-N 3.38Å; M42-T46 PolarHBondContact O-OG1 2.91Å; S43-T46 PolarHBondContact O-OG1 2.84Å; L44-T46 VanDerWaalsContact C-N 3.35Å; T46-S48 PolarHBondContact O-N 3.49Å; T46-L86 HydrophobicContact CG2-CD1 4.34Å; T46-V88 HydrophobicContact CG2-CG2 4.24Å
47	L	87	Confident	86.3	Confident	12 Å²	12	55.2 Å²	55.2	6%	0.063	28%	0.277	C	S	.	.			trans	-70.6	124.7	-171.8	-155.5	121.8	0	0	0	111.8	L39 S43 L44 L45 D51 L52 L57 L72	L39-L47 HydrophobicContact CD1-CD1 3.67Å; L39-L47 HydrophobicContact CD2-CD1 4.01Å; S43-L47 PolarHBondContact O-N 3.31Å; L44-L47 VanDerWaalsContact O-CB 3.3Å; L44-L47 WeakPolarHBondContact O-CB 3.29Å; L44-L47 PolarHBondContact O-N 2.83Å; L45-L47 VanDerWaalsContact C-N 3.29Å; L47-D51 HydrophobicContact CG-CB 4.38Å; L47-L52 HydrophobicContact CD2-CD1 4.06Å; L47-L52 HydrophobicContact CD2-CD2 3.33Å; L47-L52 HydrophobicContact CD2-CG 3.47Å; L47-L52 VanDerWaalsContact CD2-CG 3.47Å; L47-L57 HydrophobicContact CD1-CD1 4.38Å; L47-L72 HydrophobicContact CB-CD1 4.37Å; L47-L72 HydrophobicContact CD2-CD1 3.68Å
48	S	85.6	Confident	86.1	Confident	43 Å²	43	58.2 Å²	58.2	30%	0.301	29%	0.291	S	S	.	.			trans	-99.1	165.8	-179.3	77.5	0	0	0	0	112.7	T46 Y50 D51 L52	T46-S48 PolarHBondContact O-N 3.49Å; S48-Y50 PolarHBondContact O-N 3.09Å; S48-Y50 WeakPolarHBondContact OG-CB 3.24Å; S48-Y50 PolarHBondContact OG-N 2.89Å; S48-D51 VanDerWaalsContact CB-OD2 3.3Å; S48-D51 WeakPolarHBondContact CB-OD2 3.42Å; S48-D51 PolarHBondContact N-OD2 3.19Å; S48-D51 PolarHBondContact O-N 3.49Å; S48-D51 PolarHBondContact OG-N 2.86Å; S48-D51 PolarHBondContact OG-OD2 2.9Å; S48-L52 PolarHBondContact O-N 2.97Å
49	E	83.6	Confident	86	Confident	42 Å²	42	49.7 Å²	49.7	20%	0.196	26%	0.26	C	S	.	.	H	α-helix	trans	-63.3	-26.3	172.3	-177	167.6	-177.1	0	0	111.8	R53 I65 K66 M69	E49-R53 WeakPolarHBondContact O-CG 3.29Å; E49-R53 IonicContact OE1-CZ 3.48Å; E49-R53 IonicContact OE1-NE 2.63Å; E49-R53 PolarHBondContact OE1-NE 3.06Å; E49-R53 IonicContact OE1-NH2 3.2Å; E49-R53 PolarHBondContact OE1-NH2 3.3Å; E49-I65 HydrophobicContact CG-CG2 4.32Å; E49-K66 VanDerWaalsContact OE1-CE 3.28Å; E49-K66 WeakPolarHBondContact OE1-CE 3.25Å; E49-K66 IonicContact OE1-NZ 2.93Å; E49-K66 PolarHBondContact OE1-NZ 3.22Å; E49-K66 IonicContact OE2-NZ 2.7Å; E49-K66 PolarHBondContact OE2-NZ 3.41Å; E49-M69 HydrophobicContact CB-CE 4.03Å; E49-M69 HydrophobicContact CB-CG 4.1Å; E49-M69 HydrophobicContact CB-SD 3.94Å; E49-M69 HydrophobicContact CG-CG 4.27Å
50	Y	82.5	Confident	85.8	Confident	166 Å²	166	58.2 Å²	58.2	65%	0.651	30%	0.296	S	S	*	.	H	α-helix	trans	-67.7	-45.2	175.3	179.6	-95.5	0	0	0	110.9	S48 L52 R53 S54	S48-Y50 PolarHBondContact O-N 3.09Å; S48-Y50 WeakPolarHBondContact OG-CB 3.24Å; S48-Y50 PolarHBondContact OG-N 2.89Å; Y50-L52 VanDerWaalsContact C-N 3.27Å; Y50-L52 PolarHBondContact O-N 2.78Å; Y50-R53 PolarHBondContact O-N 3.31Å; Y50-S54 WeakPolarHBondContact CD2-OG 3.47Å; Y50-S54 WeakPolarHBondContact CE1-OG 3.2Å; Y50-S54 WeakPolarHBondContact CE2-OG 3.29Å; Y50-S54 VanDerWaalsContact O-CB 3.26Å; Y50-S54 WeakPolarHBondContact O-CB 3.4Å; Y50-S54 PolarHBondContact O-N 3.28Å; Y50-S54 PolarHBondContact O-OG 2.91Å
51	D	87.6	Confident	85.7	Confident	67 Å²	67	58.6 Å²	58.6	36%	0.358	30%	0.301	S	S	.	.	H	α-helix	trans	-63.9	-33.3	-177.4	-55.1	-47.6	0	0	0	112.4	L47 S48 R53 L57	L47-D51 HydrophobicContact CG-CB 4.38Å; S48-D51 VanDerWaalsContact CB-OD2 3.3Å; S48-D51 WeakPolarHBondContact CB-OD2 3.42Å; S48-D51 PolarHBondContact N-OD2 3.19Å; S48-D51 PolarHBondContact O-N 3.49Å; S48-D51 PolarHBondContact OG-N 2.86Å; S48-D51 PolarHBondContact OG-OD2 2.9Å; D51-R53 VanDerWaalsContact C-N 3.34Å; D51-L57 WeakPolarHBondContact O-CB 3.46Å; D51-L57 WeakPolarHBondContact O-CD1 3.29Å
52	L	87.8	Confident	85.5	Confident	0 Å²	0	63.4 Å²	63.4	0%	0	33%	0.326	C	S	.	.	H	α-helix	trans	-67.8	-31.9	174.8	-69.6	177.6	0	0	0	113.3	L47 S48 Y50 L57 L59 I65 L68 M69 L72	L47-L52 HydrophobicContact CD2-CD1 4.06Å; L47-L52 HydrophobicContact CD2-CD2 3.33Å; L47-L52 HydrophobicContact CD2-CG 3.47Å; L47-L52 VanDerWaalsContact CD2-CG 3.47Å; S48-L52 PolarHBondContact O-N 2.97Å; Y50-L52 VanDerWaalsContact C-N 3.27Å; Y50-L52 PolarHBondContact O-N 2.78Å; L52-L57 HydrophobicContact CD2-CD1 4.06Å; L52-L59 HydrophobicContact CB-CD1 4.17Å; L52-L59 HydrophobicContact CD2-CD1 3.72Å; L52-L59 HydrophobicContact CG-CD1 4.41Å; L52-L59 VanDerWaalsContact O-CB 3.3Å; L52-L59 WeakPolarHBondContact O-CB 3.32Å; L52-L59 WeakPolarHBondContact O-CG 3.48Å; L52-L59 PolarHBondContact O-N 2.94Å; L52-I65 HydrophobicContact CB-CG2 4.31Å; L52-I65 HydrophobicContact CD1-CG2 4.14Å; L52-L68 HydrophobicContact CD1-CD2 4.04Å; L52-L68 HydrophobicContact CD1-CG 4.38Å; L52-L68 HydrophobicContact CD2-CD2 3.72Å; L52-M69 HydrophobicContact CD1-CG 3.8Å; L52-M69 HydrophobicContact CD1-SD 3.56Å; L52-M69 VanDerWaalsContact CD1-SD 3.56Å; L52-L72 HydrophobicContact CD1-CD1 4.43Å
53	R	86.3	Confident	85.4	Confident	123 Å²	123	63 Å²	63	46%	0.464	33%	0.333	S	S	.	.	H	α-helix	trans	-93.2	-31	-173.8	-70.2	175.5	175.8	-147.6	0.9	112.8	E49 Y50 D51 I65	E49-R53 WeakPolarHBondContact O-CG 3.29Å; E49-R53 IonicContact OE1-CZ 3.48Å; E49-R53 IonicContact OE1-NE 2.63Å; E49-R53 PolarHBondContact OE1-NE 3.06Å; E49-R53 IonicContact OE1-NH2 3.2Å; E49-R53 PolarHBondContact OE1-NH2 3.3Å; Y50-R53 PolarHBondContact O-N 3.31Å; D51-R53 VanDerWaalsContact C-N 3.34Å; R53-I65 HydrophobicContact CG-CD1 3.99Å; R53-I65 HydrophobicContact CG-CG2 4.44Å
54	S	81.9	Confident	85.4	Confident	19 Å²	19	63.2 Å²	63.2	13%	0.133	33%	0.331	C	S	.	.	S	Bend	trans	-90	160	-175.1	-55.9	0	0	0	0	111.1	Y50 L57 E58	Y50-S54 WeakPolarHBondContact CD2-OG 3.47Å; Y50-S54 WeakPolarHBondContact CE1-OG 3.2Å; Y50-S54 WeakPolarHBondContact CE2-OG 3.29Å; Y50-S54 VanDerWaalsContact O-CB 3.26Å; Y50-S54 WeakPolarHBondContact O-CB 3.4Å; Y50-S54 PolarHBondContact O-N 3.28Å; Y50-S54 PolarHBondContact O-OG 2.91Å; S54-L57 PolarHBondContact O-N 3.45Å; S54-L57 VanDerWaalsContact O-N 3.14Å; S54-E58 PolarHBondContact O-N 3.06Å; S54-E58 VanDerWaalsContact O-N 3.12Å
55	P	80.4	Confident	85.2	Confident	96 Å²	96	63.3 Å²	63.3	62%	0.623	33%	0.332	S	S	*	.	T	Hydrogen-bonded Turn	trans	-55.7	135	164.3	23.1	-32.2	0	0	0	109.3	E58	P55-E58 HydrophobicContact CB-CG 4.12Å
56	P	82.3	Confident	85.3	Confident	89 Å²	89	67.9 Å²	67.9	58%	0.578	35%	0.352	S	S	*	.	T	Hydrogen-bonded Turn	cis	-100.4	0	21.5	39.4	-38.2	0	0	0	116.3	H37	H37-P56 PolarHBondContact CE1-O 2.87Å; H37-P56 PolarHBondContact NE2-O 3.37Å
57	L	85.3	Confident	85.4	Confident	16 Å²	16	73.5 Å²	73.5	8%	0.084	37%	0.366	C	S	.	.	T	Hydrogen-bonded Turn	trans	-89.1	-40.1	-175	-65.2	-178.9	0	0	0	114	L33 H37 L47 D51 L52 S54 L59	L33-L57 HydrophobicContact CD2-CD1 3.82Å; L33-L57 HydrophobicContact CD2-CD2 3.68Å; L33-L57 HydrophobicContact CD2-CG 4.39Å; H37-L57 HydrophobicContact CB-CD2 4.07Å; H37-L57 WeakPolarHBondContact CD2-CD2 3.44Å; L47-L57 HydrophobicContact CD1-CD1 4.38Å; D51-L57 WeakPolarHBondContact O-CB 3.46Å; D51-L57 WeakPolarHBondContact O-CD1 3.29Å; L52-L57 HydrophobicContact CD2-CD1 4.06Å; S54-L57 PolarHBondContact O-N 3.45Å; S54-L57 VanDerWaalsContact O-N 3.14Å; L57-L59 PolarHBondContact O-N 3.1Å
58	E	84.8	Confident	85.5	Confident	115 Å²	115	73.1 Å²	73.1	54%	0.537	36%	0.364	S	S	.	.			trans	45.7	48.7	172.7	-54.5	-172.1	143.2	0	0	115.2	S54 P55 K60	S54-E58 PolarHBondContact O-N 3.06Å; S54-E58 VanDerWaalsContact O-N 3.12Å; P55-E58 HydrophobicContact CB-CG 4.12Å; E58-K60 PolarHBondContact O-N 3.37Å
59	L	87.5	Confident	85.7	Confident	13 Å²	13	71.6 Å²	71.6	7%	0.068	35%	0.352	C	S	.	.			trans	-64.9	119.9	178.2	-65.8	-172.5	0	0	0	111.2	Y29 L32 L52 L57 I65 L68	Y29-L59 HydrophobicContact CD1-CD2 3.54Å; Y29-L59 HydrophobicContact CE1-CD2 3.3Å; L32-L59 HydrophobicContact CD2-CD2 3.72Å; L52-L59 HydrophobicContact CB-CD1 4.17Å; L52-L59 HydrophobicContact CD2-CD1 3.72Å; L52-L59 HydrophobicContact CG-CD1 4.41Å; L52-L59 VanDerWaalsContact O-CB 3.3Å; L52-L59 WeakPolarHBondContact O-CB 3.32Å; L52-L59 WeakPolarHBondContact O-CG 3.48Å; L52-L59 PolarHBondContact O-N 2.94Å; L57-L59 PolarHBondContact O-N 3.1Å; L59-I65 HydrophobicContact CB-CD1 3.86Å; L59-I65 HydrophobicContact CB-CG1 3.62Å; L59-I65 HydrophobicContact CD1-CG1 4.03Å; L59-I65 HydrophobicContact CG-CG1 4.49Å; L59-I65 WeakPolarHBondContact O-CD1 3.41Å; L59-L68 HydrophobicContact CD1-CD2 4.39Å
60	K	85.4	Confident	86	Confident	198 Å²	198	74.2 Å²	74.2	86%	0.861	37%	0.37	S	S	*	.			trans	-82.6	-25.3	-175.1	-62.2	-173.2	178.2	-178.7	0	114.2	E58	E58-K60 PolarHBondContact O-N 3.37Å
61	V	88.5	Confident	86.3	Confident	71 Å²	71	67 Å²	67	43%	0.43	34%	0.344	S	S	.	.			trans	-95.2	106.5	-173.1	-175	0	0	0	0	110.2	G63 D64 I65	V61-G63 VanDerWaalsContact C-N 3.27Å; V61-G63 PolarHBondContact O-N 3.06Å; V61-D64 HydrophobicContact CB-CB 4.25Å; V61-D64 HydrophobicContact CG1-CB 4.26Å; V61-D64 WeakPolarHBondContact CG1-OD2 3.41Å; V61-D64 PolarHBondContact O-N 3.35Å; V61-I65 WeakPolarHBondContact O-CG1 3.37Å; V61-I65 PolarHBondContact O-N 3.27Å; V61-I65 VanDerWaalsContact O-N 3.14Å
62	L	82.3	Confident	86.4	Confident	100 Å²	100	63.9 Å²	63.9	52%	0.524	33%	0.328	S	S	.	.	H	α-helix	trans	-59.9	-35.8	-177.7	-177.6	65.6	0	0	0	113.2	D64 I65 K66	L62-D64 VanDerWaalsContact C-N 3.33Å; L62-D64 PolarHBondContact O-N 3.07Å; L62-I65 PolarHBondContact O-N 2.82Å; L62-K66 HydrophobicContact CD1-CG 4.45Å; L62-K66 PolarHBondContact O-N 2.7Å
63	G	83.4	Confident	86.3	Confident	39 Å²	39	69.6 Å²	69.6	40%	0.402	35%	0.349	S	S	.	.	H	α-helix	trans	-61	-43	178.6	0	0	0	0	0	112.2	V61 K66 R67	V61-G63 VanDerWaalsContact C-N 3.27Å; V61-G63 PolarHBondContact O-N 3.06Å; G63-K66 PolarHBondContact O-N 3.17Å; G63-R67 WeakPolarHBondContact O-CG 3.39Å; G63-R67 PolarHBondContact O-N 3.38Å
64	D	87.6	Confident	86.3	Confident	52 Å²	52	69.5 Å²	69.5	28%	0.278	35%	0.352	S	S	.	.	H	α-helix	trans	-71.8	-39.7	180	-62.5	-21.5	0	0	0	111	Y29 V61 L62 K66 R67 L68	Y29-D64 HydrophobicContact CE2-CB 3.76Å; Y29-D64 PolarHBondContact OH-OD2 3.28Å; Y29-D64 VanDerWaalsContact OH-OD2 3.07Å; V61-D64 HydrophobicContact CB-CB 4.25Å; V61-D64 HydrophobicContact CG1-CB 4.26Å; V61-D64 WeakPolarHBondContact CG1-OD2 3.41Å; V61-D64 PolarHBondContact O-N 3.35Å; L62-D64 VanDerWaalsContact C-N 3.33Å; L62-D64 PolarHBondContact O-N 3.07Å; D64-K66 VanDerWaalsContact C-N 3.33Å; D64-K66 PolarHBondContact O-N 3.42Å; D64-R67 PolarHBondContact O-N 3.02Å; D64-L68 VanDerWaalsContact O-CB 3.24Å; D64-L68 WeakPolarHBondContact O-CB 3.36Å; D64-L68 PolarHBondContact O-N 2.93Å
65	I	86.3	Confident	86.5	Confident	5 Å²	5	69 Å²	69	3%	0.026	35%	0.348	C	S	.	.	H	α-helix	trans	-55.8	-48.7	172.4	-65.4	162.9	0	0	0	110.5	E49 L52 R53 L59 V61 L62 L68 M69	E49-I65 HydrophobicContact CG-CG2 4.32Å; L52-I65 HydrophobicContact CB-CG2 4.31Å; L52-I65 HydrophobicContact CD1-CG2 4.14Å; R53-I65 HydrophobicContact CG-CD1 3.99Å; R53-I65 HydrophobicContact CG-CG2 4.44Å; L59-I65 HydrophobicContact CB-CD1 3.86Å; L59-I65 HydrophobicContact CB-CG1 3.62Å; L59-I65 HydrophobicContact CD1-CG1 4.03Å; L59-I65 HydrophobicContact CG-CG1 4.49Å; L59-I65 WeakPolarHBondContact O-CD1 3.41Å; V61-I65 WeakPolarHBondContact O-CG1 3.37Å; V61-I65 PolarHBondContact O-N 3.27Å; V61-I65 VanDerWaalsContact O-N 3.14Å; L62-I65 PolarHBondContact O-N 2.82Å; I65-L68 PolarHBondContact O-N 3.45Å; I65-M69 HydrophobicContact CG2-CG 4.47Å; I65-M69 WeakPolarHBondContact O-CB 3.17Å; I65-M69 VanDerWaalsContact O-CG 3.29Å; I65-M69 WeakPolarHBondContact O-CG 3.34Å; I65-M69 PolarHBondContact O-N 3Å
66	K	88.6	Confident	86.8	Confident	98 Å²	98	65.5 Å²	65.5	43%	0.426	32%	0.323	S	S	.	.	H	α-helix	trans	-67.9	-40.3	-178.2	-73	-58.5	-168.3	-173.5	0	112.6	E49 L62 G63 D64 M69 V70	E49-K66 VanDerWaalsContact OE1-CE 3.28Å; E49-K66 WeakPolarHBondContact OE1-CE 3.25Å; E49-K66 IonicContact OE1-NZ 2.93Å; E49-K66 PolarHBondContact OE1-NZ 3.22Å; E49-K66 IonicContact OE2-NZ 2.7Å; E49-K66 PolarHBondContact OE2-NZ 3.41Å; L62-K66 HydrophobicContact CD1-CG 4.45Å; L62-K66 PolarHBondContact O-N 2.7Å; G63-K66 PolarHBondContact O-N 3.17Å; D64-K66 VanDerWaalsContact C-N 3.33Å; D64-K66 PolarHBondContact O-N 3.42Å; K66-M69 PolarHBondContact O-N 3.49Å; K66-V70 WeakPolarHBondContact O-CG2 3.32Å; K66-V70 PolarHBondContact O-N 3.07Å; K66-V70 VanDerWaalsContact O-N 3.16Å
67	R	87.9	Confident	86.8	Confident	180 Å²	180	68.5 Å²	68.5	68%	0.679	33%	0.327	S	S	*	.	H	α-helix	trans	-65.1	-43.7	176.3	-69.8	176.3	-178.8	-145.6	1.7	111.1	F26 G63 D64 M69 V70 S71	F26-R67 HydrophobicContact CE1-CB 4.06Å; F26-R67 HydrophobicContact CZ-CB 3.68Å; G63-R67 WeakPolarHBondContact O-CG 3.39Å; G63-R67 PolarHBondContact O-N 3.38Å; D64-R67 PolarHBondContact O-N 3.02Å; R67-M69 PolarHBondContact O-N 3.14Å; R67-V70 PolarHBondContact O-N 3.05Å; R67-V70 VanDerWaalsContact O-N 3.17Å; R67-S71 PolarHBondContact O-N 3.4Å; R67-S71 VanDerWaalsContact O-N 3.14Å
68	L	90.6	Very high	86.7	Confident	3 Å²	3	73.8 Å²	73.8	2%	0.016	35%	0.351	C	S	.	.	H	α-helix	trans	-63.3	-42.9	177.9	-177.2	60.2	0	0	0	111.3	W20 L21 F26 L33 L52 L59 D64 I65 V70 S71 L72	W20-L68 HydrophobicContact CZ3-CD1 4.34Å; L21-L68 HydrophobicContact CD2-CD1 3.88Å; F26-L68 HydrophobicContact CD1-CB 4.41Å; F26-L68 HydrophobicContact CD2-CD1 3.87Å; F26-L68 HydrophobicContact CE1-CB 3.89Å; F26-L68 HydrophobicContact CE2-CB 4.28Å; F26-L68 HydrophobicContact CE2-CD1 3.95Å; F26-L68 HydrophobicContact CG-CD1 4.19Å; F26-L68 VanDerWaalsContact CZ-CA 3.47Å; F26-L68 HydrophobicContact CZ-CB 3.83Å; F26-L68 HydrophobicContact CZ-CD1 4.34Å; F26-L68 VanDerWaalsContact CZ-N 3.26Å; L33-L68 HydrophobicContact CD1-CD2 4.26Å; L52-L68 HydrophobicContact CD1-CD2 4.04Å; L52-L68 HydrophobicContact CD1-CG 4.38Å; L52-L68 HydrophobicContact CD2-CD2 3.72Å; L59-L68 HydrophobicContact CD1-CD2 4.39Å; D64-L68 VanDerWaalsContact O-CB 3.24Å; D64-L68 WeakPolarHBondContact O-CB 3.36Å; D64-L68 PolarHBondContact O-N 2.93Å; I65-L68 PolarHBondContact O-N 3.45Å; L68-V70 VanDerWaalsContact C-N 3.27Å; L68-V70 PolarHBondContact O-N 2.91Å; L68-S71 PolarHBondContact O-N 2.93Å; L68-L72 HydrophobicContact CD1-CG 4.45Å; L68-L72 HydrophobicContact CG-CD1 4.07Å; L68-L72 HydrophobicContact CG-CG 4.4Å; L68-L72 WeakPolarHBondContact O-CB 3.48Å; L68-L72 VanDerWaalsContact O-CG 3.29Å; L68-L72 WeakPolarHBondContact O-CG 3.43Å; L68-L72 PolarHBondContact O-N 2.86Å
69	M	89.8	Confident	86.7	Confident	12 Å²	12	69.5 Å²	69.5	6%	0.059	33%	0.332	C	S	.	.	H	α-helix	trans	-61.3	-32.5	175	-76.5	-55.6	-55.8	0	0	113.4	E49 L52 I65 K66 R67 L72 R73	E49-M69 HydrophobicContact CB-CE 4.03Å; E49-M69 HydrophobicContact CB-CG 4.1Å; E49-M69 HydrophobicContact CB-SD 3.94Å; E49-M69 HydrophobicContact CG-CG 4.27Å; L52-M69 HydrophobicContact CD1-CG 3.8Å; L52-M69 HydrophobicContact CD1-SD 3.56Å; L52-M69 VanDerWaalsContact CD1-SD 3.56Å; I65-M69 HydrophobicContact CG2-CG 4.47Å; I65-M69 WeakPolarHBondContact O-CB 3.17Å; I65-M69 VanDerWaalsContact O-CG 3.29Å; I65-M69 WeakPolarHBondContact O-CG 3.34Å; I65-M69 PolarHBondContact O-N 3Å; K66-M69 PolarHBondContact O-N 3.49Å; R67-M69 PolarHBondContact O-N 3.14Å; M69-L72 HydrophobicContact SD-CD1 3.98Å; M69-R73 WeakPolarHBondContact O-CB 3.36Å; M69-R73 VanDerWaalsContact O-CG 3.29Å; M69-R73 WeakPolarHBondContact O-CG 3.49Å; M69-R73 PolarHBondContact O-N 3.45Å
70	V	88.6	Confident	86.3	Confident	96 Å²	96	71.9 Å²	71.9	58%	0.582	35%	0.345	S	S	*	.	H	α-helix	trans	-68.9	-45.5	175.1	170.6	0	0	0	0	110.6	K66 R67 L68 L72 R73 K74	K66-V70 WeakPolarHBondContact O-CG2 3.32Å; K66-V70 PolarHBondContact O-N 3.07Å; K66-V70 VanDerWaalsContact O-N 3.16Å; R67-V70 PolarHBondContact O-N 3.05Å; R67-V70 VanDerWaalsContact O-N 3.17Å; L68-V70 VanDerWaalsContact C-N 3.27Å; L68-V70 PolarHBondContact O-N 2.91Å; V70-L72 VanDerWaalsContact C-N 3.34Å; V70-L72 PolarHBondContact O-N 3.33Å; V70-R73 PolarHBondContact O-N 3.03Å; V70-K74 PolarHBondContact O-N 2.71Å
71	S	88.9	Confident	86	Confident	15 Å²	15	67.4 Å²	67.4	11%	0.105	33%	0.33	C	S	.	.	H	α-helix	trans	-63	-39.7	175.3	-62.3	0	0	0	0	112	E24 R67 L68 K74 L75	E24-S71 VanDerWaalsContact OE2-CB 3.25Å; E24-S71 WeakPolarHBondContact OE2-CB 3.46Å; E24-S71 PolarHBondContact OE2-OG 2.96Å; R67-S71 PolarHBondContact O-N 3.4Å; R67-S71 VanDerWaalsContact O-N 3.14Å; L68-S71 PolarHBondContact O-N 2.93Å; S71-K74 WeakPolarHBondContact O-CB 3.41Å; S71-K74 PolarHBondContact O-N 2.68Å; S71-L75 PolarHBondContact O-N 3.1Å
72	L	89.6	Confident	85.5	Confident	1 Å²	1	64.1 Å²	64.1	1%	0.005	31%	0.31	C	S	.	.	H	α-helix	trans	-63.4	-45.3	174.8	-73.5	171.9	0	0	0	112.4	W20 L44 L47 L52 L68 M69 V70 K74 L75 Q76	W20-L72 HydrophobicContact CH2-CD2 4.08Å; W20-L72 HydrophobicContact CH2-CG 4.46Å; W20-L72 HydrophobicContact CZ3-CD2 4.38Å; L44-L72 HydrophobicContact CD1-CD2 3.58Å; L44-L72 HydrophobicContact CD2-CD2 4.47Å; L44-L72 HydrophobicContact CG-CD2 3.64Å; L44-L72 WeakPolarHBondContact O-CD2 3.24Å; L47-L72 HydrophobicContact CB-CD1 4.37Å; L47-L72 HydrophobicContact CD2-CD1 3.68Å; L52-L72 HydrophobicContact CD1-CD1 4.43Å; L68-L72 HydrophobicContact CD1-CG 4.45Å; L68-L72 HydrophobicContact CG-CD1 4.07Å; L68-L72 HydrophobicContact CG-CG 4.4Å; L68-L72 WeakPolarHBondContact O-CB 3.48Å; L68-L72 VanDerWaalsContact O-CG 3.29Å; L68-L72 WeakPolarHBondContact O-CG 3.43Å; L68-L72 PolarHBondContact O-N 2.86Å; M69-L72 HydrophobicContact SD-CD1 3.98Å; V70-L72 VanDerWaalsContact C-N 3.34Å; V70-L72 PolarHBondContact O-N 3.33Å; L72-K74 VanDerWaalsContact C-N 3.29Å; L72-K74 PolarHBondContact O-N 3.14Å; L72-L75 CarbonylContact O-C 3.59Å; L72-L75 WeakPolarHBondContact O-CB 3.26Å; L72-L75 PolarHBondContact O-N 2.88Å; L72-L75 VanDerWaalsContact O-N 3.11Å; L72-Q76 WeakPolarHBondContact O-CG 3.22Å; L72-Q76 PolarHBondContact O-N 3.04Å
73	R	86.6	Confident	85.3	Confident	121 Å²	121	59.5 Å²	59.5	46%	0.457	29%	0.286	S	S	.	.	H	α-helix	trans	-63.6	-35	176.1	-76.7	177.9	-176.4	166.8	2.1	112.7	M69 V70 L75 K77	M69-R73 WeakPolarHBondContact O-CB 3.36Å; M69-R73 VanDerWaalsContact O-CG 3.29Å; M69-R73 WeakPolarHBondContact O-CG 3.49Å; M69-R73 PolarHBondContact O-N 3.45Å; V70-R73 PolarHBondContact O-N 3.03Å; R73-L75 VanDerWaalsContact C-N 3.33Å; R73-K77 VanDerWaalsContact O-CB 3.32Å; R73-K77 WeakPolarHBondContact O-CB 3.27Å; R73-K77 PolarHBondContact O-N 2.86Å
74	K	85.9	Confident	84.8	Confident	121 Å²	121	64.5 Å²	64.5	53%	0.526	30%	0.299	S	S	.	.	H	α-helix	trans	-63.8	-41.8	173.4	-174.1	-176.8	175.3	-168.7	0	110.7	V70 S71 L72 K77 Q78	V70-K74 PolarHBondContact O-N 2.71Å; S71-K74 WeakPolarHBondContact O-CB 3.41Å; S71-K74 PolarHBondContact O-N 2.68Å; L72-K74 VanDerWaalsContact C-N 3.29Å; L72-K74 PolarHBondContact O-N 3.14Å; K74-K77 PolarHBondContact O-N 3.43Å; K74-Q78 WeakPolarHBondContact O-CG 3.46Å; K74-Q78 PolarHBondContact O-N 3.34Å
75	L	86	Confident	84.1	Confident	8 Å²	8	68.6 Å²	68.6	4%	0.042	32%	0.316	C	S	.	.	H	α-helix	trans	-67.3	-43.5	176.8	-167.2	67.8	0	0	0	112.2	I9 W12 W20 L44 L45 S71 L72 R73 K77 Q78 N79	I9-L75 HydrophobicContact CD1-CD1 4.02Å; I9-L75 HydrophobicContact CD1-CD2 3.95Å; I9-L75 HydrophobicContact CD1-CG 4.16Å; W12-L75 HydrophobicContact CH2-CD1 4.22Å; W12-L75 HydrophobicContact CZ3-CD2 4.42Å; W20-L75 HydrophobicContact CH2-CD2 4.46Å; W20-L75 HydrophobicContact CZ2-CB 4.31Å; W20-L75 HydrophobicContact CZ2-CD2 4.05Å; L44-L75 HydrophobicContact CD2-CD2 3.58Å; L44-L75 HydrophobicContact CG-CD2 4.27Å; L45-L75 HydrophobicContact CD2-CD2 4.34Å; L45-L75 HydrophobicContact CD2-CG 4.06Å; S71-L75 PolarHBondContact O-N 3.1Å; L72-L75 CarbonylContact O-C 3.59Å; L72-L75 WeakPolarHBondContact O-CB 3.26Å; L72-L75 PolarHBondContact O-N 2.88Å; L72-L75 VanDerWaalsContact O-N 3.11Å; R73-L75 VanDerWaalsContact C-N 3.33Å; L75-K77 PolarHBondContact O-N 3.49Å; L75-Q78 PolarHBondContact O-N 2.92Å; L75-N79 PolarHBondContact O-N 3.37Å; L75-N79 PolarHBondContact O-ND2 3.36Å
76	Q	86.9	Confident	83.3	Confident	23 Å²	23	72.2 Å²	72.2	11%	0.107	34%	0.335	C	S	.	.	H	α-helix	trans	-60.7	-43.3	174.1	-72.8	169.1	-23	0	0	111.5	L45 L72 Q78 N79 L80 L83 F90	L45-Q76 HydrophobicContact CD2-CG 4.22Å; L45-Q76 WeakPolarHBondContact O-CG 3.2Å; L45-Q76 PolarHBondContact O-NE2 2.7Å; L72-Q76 WeakPolarHBondContact O-CG 3.22Å; L72-Q76 PolarHBondContact O-N 3.04Å; Q76-Q78 PolarHBondContact O-N 3.23Å; Q76-N79 CarbonylContact O-C 3.35Å; Q76-N79 PolarHBondContact O-N 2.97Å; Q76-L80 PolarHBondContact O-N 3.39Å; Q76-L83 HydrophobicContact CB-CD2 4.39Å; Q76-F90 HydrophobicContact CB-CD2 4Å; Q76-F90 HydrophobicContact CB-CE2 3.5Å; Q76-F90 HydrophobicContact CB-CZ 4.42Å; Q76-F90 HydrophobicContact CG-CE2 4.46Å
77	K	83.3	Confident	82.1	Confident	152 Å²	152	70.7 Å²	70.7	66%	0.661	35%	0.347	S	S	*	.	H	α-helix	trans	-60.7	-33	176.3	-171.1	177	179.9	-179.6	0	112.6	R73 K74 L75 N79 F90	R73-K77 VanDerWaalsContact O-CB 3.32Å; R73-K77 WeakPolarHBondContact O-CB 3.27Å; R73-K77 PolarHBondContact O-N 2.86Å; K74-K77 PolarHBondContact O-N 3.43Å; L75-K77 PolarHBondContact O-N 3.49Å; K77-N79 VanDerWaalsContact C-N 3.29Å; K77-F90 HydrophobicContact CB-CZ 4.28Å
78	Q	82.5	Confident	81	Confident	126 Å²	126	64.8 Å²	64.8	59%	0.589	33%	0.331	S	S	*	.	H	α-helix	trans	-77.2	-14.1	178.1	-72.6	173.4	-17	0	0	113.5	K74 L75 Q76	K74-Q78 WeakPolarHBondContact O-CG 3.46Å; K74-Q78 PolarHBondContact O-N 3.34Å; L75-Q78 PolarHBondContact O-N 2.92Å; Q76-Q78 PolarHBondContact O-N 3.23Å
79	N	84.9	Confident	79.4	Confident	26 Å²	26	69.9 Å²	69.9	14%	0.139	37%	0.365	C	S	.	.	T	Hydrogen-bonded Turn	trans	-131.7	42.2	-174.3	-62.1	-88.3	0	0	0	110.8	I9 L45 L75 Q76 K77 D81 I82 L83	I9-N79 HydrophobicContact CG2-CB 4.28Å; I9-N79 VanDerWaalsContact CG2-OD1 3.3Å; I9-N79 WeakPolarHBondContact CG2-OD1 3.3Å; L45-N79 HydrophobicContact CD1-CB 4.26Å; L45-N79 HydrophobicContact CD2-CB 4.17Å; L75-N79 PolarHBondContact O-N 3.37Å; L75-N79 PolarHBondContact O-ND2 3.36Å; Q76-N79 CarbonylContact O-C 3.35Å; Q76-N79 PolarHBondContact O-N 2.97Å; K77-N79 VanDerWaalsContact C-N 3.29Å; N79-D81 VanDerWaalsContact C-N 3.32Å; N79-D81 VanDerWaalsContact C-OD1 3.27Å; N79-D81 PolarHBondContact O-N 2.76Å; N79-I82 HydrophobicContact CB-CD1 4.27Å; N79-I82 PolarHBondContact O-N 3.17Å; N79-L83 PolarHBondContact O-N 3.1Å
80	L	79.6	Confident	77.8	Confident	62 Å²	62	72.4 Å²	72.4	33%	0.325	38%	0.376	S	S	.	.	H	α-helix	trans	-63.8	-38.2	-173.7	-134.7	104.9	0	0	0	112.3	Q76 I82 L83 E84 F90	Q76-L80 PolarHBondContact O-N 3.39Å; L80-I82 VanDerWaalsContact C-N 3.27Å; L80-I82 PolarHBondContact O-N 3.08Å; L80-L83 PolarHBondContact O-N 3.16Å; L80-L83 VanDerWaalsContact O-N 3.1Å; L80-E84 PolarHBondContact O-N 2.95Å; L80-F90 HydrophobicContact CD1-CD1 3.87Å; L80-F90 HydrophobicContact CD1-CE1 3.91Å; L80-F90 HydrophobicContact CD1-CG 4.45Å
81	D	77.8	Confident	75.9	Confident	105 Å²	105	74.4 Å²	74.4	56%	0.561	38%	0.383	S	S	*	.	H	α-helix	trans	-56.3	-39.8	176	57.2	-45.9	0	0	0	112.3	N79 E85	N79-D81 VanDerWaalsContact C-N 3.32Å; N79-D81 VanDerWaalsContact C-OD1 3.27Å; N79-D81 PolarHBondContact O-N 2.76Å; D81-E85 PolarHBondContact O-N 2.8Å
82	I	79.3	Confident	73.8	Confident	2 Å²	2	75.8 Å²	75.8	1%	0.01	40%	0.399	C	S	.	.	H	α-helix	trans	-74.3	-33.8	178.4	-59.1	174.5	0	0	0	110.8	I9 R10 M42 L45 N79 L80 L86	I9-I82 HydrophobicContact CG2-CD1 3.29Å; R10-I82 HydrophobicContact CG-CD1 3.96Å; R10-I82 HydrophobicContact CG-CG2 4.42Å; M42-I82 HydrophobicContact CE-CG2 3.79Å; M42-I82 HydrophobicContact SD-CG2 4.19Å; L45-I82 HydrophobicContact CD1-CG2 4.32Å; N79-I82 HydrophobicContact CB-CD1 4.27Å; N79-I82 PolarHBondContact O-N 3.17Å; L80-I82 VanDerWaalsContact C-N 3.27Å; L80-I82 PolarHBondContact O-N 3.08Å; I82-L86 HydrophobicContact CG2-CD1 4.24Å; I82-L86 WeakPolarHBondContact O-CD1 3.37Å; I82-L86 VanDerWaalsContact O-CG 3.26Å; I82-L86 WeakPolarHBondContact O-CG 3.43Å; I82-L86 PolarHBondContact O-N 2.56Å
83	L	76.4	Confident	71.2	Confident	3 Å²	3	83.9 Å²	83.9	2%	0.016	44%	0.437	C	S	.	.	H	α-helix	trans	-74.6	-35.6	-179.1	-161.4	63.5	0	0	0	112.1	Q76 N79 L80 L86 G87 V88 F90	Q76-L83 HydrophobicContact CB-CD2 4.39Å; N79-L83 PolarHBondContact O-N 3.1Å; L80-L83 PolarHBondContact O-N 3.16Å; L80-L83 VanDerWaalsContact O-N 3.1Å; L83-L86 PolarHBondContact O-N 3.31Å; L83-G87 PolarHBondContact O-N 3.03Å; L83-V88 HydrophobicContact CD1-CB 3.73Å; L83-V88 HydrophobicContact CD1-CG1 4.01Å; L83-V88 HydrophobicContact CD1-CG2 4.38Å; L83-V88 HydrophobicContact CG-CB 4.18Å; L83-V88 PolarHBondContact O-N 3.22Å; L83-F90 HydrophobicContact CD2-CB 3.69Å; L83-F90 HydrophobicContact CD2-CD2 3.6Å; L83-F90 HydrophobicContact CD2-CG 3.99Å
84	E	74.1	Confident	68.6	Low	144 Å²	144	83 Å²	83	67%	0.673	45%	0.449	S	S	*	.	H	α-helix	trans	-64.5	-41.2	171.8	-76	-177.3	175.1	0	0	112	L80 L86 G87	L80-E84 PolarHBondContact O-N 2.95Å; E84-L86 PolarHBondContact O-N 3.2Å; E84-G87 PolarHBondContact O-N 2.97Å; E84-G87 VanDerWaalsContact O-N 3.15Å
85	E	73.6	Confident	66.2	Low	137 Å²	137	83.3 Å²	83.3	64%	0.64	46%	0.463	S	S	*	.	H	α-helix	trans	-62.5	-29.5	175.2	-169.1	178.5	135.7	0	0	112.6	R10 D81	R10-E85 IonicContact CZ-OE1 2.68Å; R10-E85 IonicContact CZ-OE2 3.64Å; R10-E85 IonicContact NH1-OE1 2.66Å; R10-E85 PolarHBondContact NH1-OE1 3.12Å; R10-E85 IonicContact NH1-OE2 2.94Å; R10-E85 PolarHBondContact NH1-OE2 3.19Å; R10-E85 VanDerWaalsContact NH2-CD 3.26Å; R10-E85 IonicContact NH2-OE1 3.53Å; R10-E85 PolarHBondContact NH2-OE1 3.08Å; R10-E85 IonicContact NH2-OE2 3.43Å; R10-E85 PolarHBondContact NH2-OE2 2.91Å; D81-E85 PolarHBondContact O-N 2.8Å
86	L	69.4	Low	63.4	Low	81 Å²	81	92 Å²	92	42%	0.424	50%	0.504	S	S	.	.	T	Hydrogen-bonded Turn	trans	-85	-5.4	178.5	-66.5	164.8	0	0	0	113.9	M42 T46 I82 L83 E84 V88	M42-L86 HydrophobicContact CE-CD1 3.51Å; M42-L86 HydrophobicContact CE-CD2 4.07Å; M42-L86 HydrophobicContact CE-CG 4.23Å; T46-L86 HydrophobicContact CG2-CD1 4.34Å; I82-L86 HydrophobicContact CG2-CD1 4.24Å; I82-L86 WeakPolarHBondContact O-CD1 3.37Å; I82-L86 VanDerWaalsContact O-CG 3.26Å; I82-L86 WeakPolarHBondContact O-CG 3.43Å; I82-L86 PolarHBondContact O-N 2.56Å; L83-L86 PolarHBondContact O-N 3.31Å; E84-L86 PolarHBondContact O-N 3.2Å; L86-V88 HydrophobicContact CB-CG2 4.09Å; L86-V88 PolarHBondContact O-N 3.36Å
87	G	61.9	Low	60.6	Low	66 Å²	66	95 Å²	95	68%	0.68	54%	0.54	S	S	*	.	T	Hydrogen-bonded Turn	trans	65.9	20.7	-178.2	0	0	0	0	0	114.5	L83 E84	L83-G87 PolarHBondContact O-N 3.03Å; E84-G87 PolarHBondContact O-N 2.97Å; E84-G87 VanDerWaalsContact O-N 3.15Å
88	V	65.4	Low	57.8	Low	56 Å²	56	91.7 Å²	91.7	34%	0.339	55%	0.549	S	S	.	.			trans	-90.7	118	178.6	-179.3	0	0	0	0	108.8	T46 L83 L86 F90	T46-V88 HydrophobicContact CG2-CG2 4.24Å; L83-V88 HydrophobicContact CD1-CB 3.73Å; L83-V88 HydrophobicContact CD1-CG1 4.01Å; L83-V88 HydrophobicContact CD1-CG2 4.38Å; L83-V88 HydrophobicContact CG-CB 4.18Å; L83-V88 PolarHBondContact O-N 3.22Å; L86-V88 HydrophobicContact CB-CG2 4.09Å; L86-V88 PolarHBondContact O-N 3.36Å; V88-F90 PolarHBondContact O-N 3.48Å; V88-F90 VanDerWaalsContact O-N 3.07Å
89	P	56.6	Low	55.2	Low	110 Å²	110	90 Å²	90	71%	0.714	57%	0.565	S	S	*	*			trans	-66.1	113.1	-178.1	23.9	-30.6	0	0	0	110.5	D91	P89-D91 PolarHBondContact O-N 3.38Å
90	F	55.6	Low	52.4	Low	66 Å²	66	92.2 Å²	92.2	29%	0.289	60%	0.595	S	S	.	*			trans	-77.6	98.1	169	-171.9	-110.9	0	0	0	109.2	Q76 K77 L80 L83 V88 G92	Q76-F90 HydrophobicContact CB-CD2 4Å; Q76-F90 HydrophobicContact CB-CE2 3.5Å; Q76-F90 HydrophobicContact CB-CZ 4.42Å; Q76-F90 HydrophobicContact CG-CE2 4.46Å; K77-F90 HydrophobicContact CB-CZ 4.28Å; L80-F90 HydrophobicContact CD1-CD1 3.87Å; L80-F90 HydrophobicContact CD1-CE1 3.91Å; L80-F90 HydrophobicContact CD1-CG 4.45Å; L83-F90 HydrophobicContact CD2-CB 3.69Å; L83-F90 HydrophobicContact CD2-CD2 3.6Å; L83-F90 HydrophobicContact CD2-CG 3.99Å; V88-F90 PolarHBondContact O-N 3.48Å; V88-F90 VanDerWaalsContact O-N 3.07Å; F90-G92 PolarHBondContact O-N 2.98Å
91	D	49.2	Very low	49.8	Very low	138 Å²	138	96.3 Å²	96.3	74%	0.738	62%	0.617	S	S	*	*			trans	-72.6	70	167.8	-86.7	-29.3	0	0	0	110	P89 H93	P89-D91 PolarHBondContact O-N 3.38Å; D91-H93 PolarHBondContact O-N 2.97Å
92	G	45.8	Very low	47.4	Very low	43 Å²	43	103 Å²	103	44%	0.443	63%	0.634	S	S	.	*			trans	-73.3	59.7	179.6	0	0	0	0	0	113	F90	F90-G92 PolarHBondContact O-N 2.98Å
93	H	34.1	Very low	44.9	Very low	172 Å²	172	110.5 Å²	110.5	80%	0.796	67%	0.669	S	S	*	*			trans	-98.1	87.6	169.4	-76.2	77.3	0	0	0	110.5	D91	D91-H93 PolarHBondContact O-N 2.97Å
94	S	32	Very low	42.4	Very low	101 Å²	101	116.1 Å²	116.1	71%	0.706	71%	0.708	S	S	*	*			trans	-103	143	146.9	-74.4	0	0	0	0	108.8	Q96	S94-Q96 PolarHBondContact O-N 3.18Å; S94-Q96 VanDerWaalsContact O-N 3.16Å
95	P	35.8	Very low	40.2	Very low	128 Å²	128	117.3 Å²	117.3	83%	0.831	72%	0.718	S	S	*	*	S	Bend	trans	-82.5	100.5	-159.5	31.9	-32.2	0	0	0	111.2
96	Q	28.1	Very low	38	Very low	192 Å²	192	114.5 Å²	114.5	90%	0.897	73%	0.727	S	S	*	*			trans	-158.6	106.3	161.2	-111.5	163.6	24.8	0	0	111.2	S94	S94-Q96 PolarHBondContact O-N 3.18Å; S94-Q96 VanDerWaalsContact O-N 3.16Å
97	G	26.6	Very low	35.9	Very low	84 Å²	84	117.6 Å²	117.6	87%	0.866	74%	0.743	S	S	*	*			trans	57.6	115.3	142.7	0	0	0	0	0	121.4
98	G	25.3	Very low	34.2	Very low	83 Å²	83	119.5 Å²	119.5	86%	0.856	75%	0.746	S	S	*	*			trans	112.1	103.1	132.8	0	0	0	0	0	118.4
99	G	27.3	Very low	32.4	Very low	90 Å²	90	121.1 Å²	121.1	93%	0.928	76%	0.76	S	S	*	*			trans	19.6	136.5	145.6	0	0	0	0	0	123.1
100	G	26.1	Very low	31.2	Very low	73 Å²	73	127 Å²	127	75%	0.753	77%	0.768	S	S	*	*			trans	167	112.2	156.7	0	0	0	0	0	113.1
101	D	26.3	Very low	29.8	Very low	148 Å²	148	133.1 Å²	133.1	79%	0.791	80%	0.798	S	S	*	*			trans	-54.2	143.9	-179.9	-68.9	-52.9	0	0	0	115.2
102	W	26.2	Very low	28.8	Very low	245 Å²	245	132.5 Å²	132.5	93%	0.928	80%	0.803	S	S	*	*			trans	-136.5	103.9	149.9	-90.8	78	0	0	0	109.9
103	H	26.5	Very low	27.8	Very low	160 Å²	160	138.7 Å²	138.7	74%	0.741	83%	0.826	S	S	*	*			trans	-62.6	145.2	158	-88.1	-109.6	0	0	0	110
104	C	24.9	Very low	27.5	Very low	122 Å²	122	137 Å²	137	82%	0.824	82%	0.822	S	S	*	*			trans	-155.5	119	140.8	-101.9	0	0	0	0	110.7
105	N	27.9	Very low	27.2	Very low	168 Å²	168	137.8 Å²	137.8	90%	0.898	83%	0.828	S	S	*	*			trans	-60	153.6	162.5	-94.1	-16.6	0	0	0	111
106	G	26.4	Very low	26.8	Very low	79 Å²	79	138.2 Å²	138.2	81%	0.814	82%	0.823	S	S	*	*			trans	175.9	72.4	167.2	0	0	0	0	0	111.7
107	D	26.1	Very low	26.8	Very low	145 Å²	145	136 Å²	136	78%	0.775	82%	0.823	S	S	*	*			trans	-83.7	129.6	168.3	-172.5	13.9	0	0	0	109.8
108	S	26.9	Very low	26.9	Very low	106 Å²	106	139 Å²	139	74%	0.741	82%	0.82	S	S	*	*				177.7	108.8	129.2	-79.7	0	0	0	0	112.1
109	S	26.6	Very low	27.1	Very low	90 Å²	90	142 Å²	142	63%	0.629	82%	0.821	S	S	*	*				48.2	116.5	127.1	-57.4	0	0	0	0	122.4
110	R	32.3	Very low	27.2	Very low	233 Å²	233	141.8 Å²	141.8	88%	0.879	81%	0.811	S	S	*	*			trans	54.8	120.8	133.1	-65.7	-177.8	169.2	127.5	-2	119.5
111	E	24.6	Very low	27.8	Very low	196 Å²	196	144.1 Å²	144.1	92%	0.916	81%	0.812	S	S	*	*				-162.3	136.5	117.2	-109	167.4	175.5	0	0	111.2
112	C	29.2	Very low	28.1	Very low	125 Å²	125	144.2 Å²	144.2	85%	0.845	82%	0.818	S	S	*	*			trans	-80.1	131.3	167.8	-70.3	0	0	0	0	107.5
113	D	25.6	Very low	28.1	Very low	172 Å²	172	135.9 Å²	135.9	92%	0.92	81%	0.808	S	S	*	*			trans	-155.4	153	142.2	-114.4	-21.7	0	0	0	114.2
114	N	26.7	Very low	28.2	Very low	137 Å²	137	136.2 Å²	136.2	73%	0.733	81%	0.81	S	S	*	*			trans	-89.8	142.3	-162.1	-159.6	22.9	0	0	0	111.1
115	S	26.8	Very low	28.5	Very low	118 Å²	118	138.4 Å²	138.4	83%	0.825	81%	0.808	S	S	*	*			trans	-164.8	123.2	142.5	41.9	0	0	0	0	112
116	N	26	Very low	28.4	Very low	136 Å²	136	140 Å²	140	73%	0.727	80%	0.803	S	S	*	*			trans	-64.4	141.1	166.5	-73.8	-21.3	0	0	0	110.6
117	T	29.4	Very low	28.6	Very low	146 Å²	146	141.3 Å²	141.3	90%	0.896	79%	0.791	S	S	*	*			trans	-150	123	133	29.2	0	0	0	0	109.7
118	D	27.4	Very low	28.5	Very low	148 Å²	148	142.2 Å²	142.2	79%	0.791	79%	0.791	S	S	*	*			trans	-64.9	135.1	172.7	-66.4	-59.7	0	0	0	111.6
119	T	29.6	Very low	28.8	Very low	145 Å²	145	147.3 Å²	147.3	89%	0.89	80%	0.795	S	S	*	*			trans	-162.5	116	132	-24.5	0	0	0	0	110.5
120	A	29.3	Very low	28.8	Very low	86 Å²	86	148.8 Å²	148.8	71%	0.711	80%	0.801	S	S	*	*			trans	-96.2	154.9	155.8	0	0	0	0	0	108
121	P	38.4	Very low	29	Very low	121 Å²	121	145.7 Å²	145.7	79%	0.786	80%	0.801	S	S	*	*				-142.1	150.3	90.3	31.3	-12.7	0	0	0	115.9
122	V	32.9	Very low	29.2	Very low	150 Å²	150	139.4 Å²	139.4	91%	0.909	79%	0.789	S	S	*	*			trans	-2.9	127.8	150.3	-173.4	0	0	0	0	117.8
123	G	27.1	Very low	29.2	Very low	70 Å²	70	142.8 Å²	142.8	72%	0.722	79%	0.79	S	S	*	*			trans	-177.4	89.6	165.9	0	0	0	0	0	113.8
124	E	28.8	Very low	29.6	Very low	168 Å²	168	145.2 Å²	145.2	79%	0.785	79%	0.787	S	S	*	*			trans	38.6	107.3	157.3	-65.6	-170.5	126.1	0	0	121.4	Y126	E124-Y126 PolarHBondContact O-N 3.3Å
125	Q	29.5	Very low	29.6	Very low	168 Å²	168	148.3 Å²	148.3	79%	0.785	79%	0.794	S	S	*	*			trans	-74.3	92	169.4	-175.2	169.3	-6.6	0	0	111.4	L127	Q125-L127 HydrophobicContact CG-CD1 4.29Å; Q125-L127 HydrophobicContact CG-CG 4.45Å; Q125-L127 PolarHBondContact O-N 3.48Å
126	Y	27.4	Very low	30	Very low	200 Å²	200	151.6 Å²	151.6	78%	0.784	80%	0.796	S	S	*	*			trans	-88.6	87.4	155.5	-82.1	-88.1	0	0	0	109.2	E124 Q128	E124-Y126 PolarHBondContact O-N 3.3Å; Y126-Q128 VanDerWaalsContact C-N 3.25Å; Y126-Q128 PolarHBondContact O-N 3.47Å
127	L	29.6	Very low	30.1	Very low	107 Å²	107	148.3 Å²	148.3	56%	0.56	80%	0.795	S	S	*	*			trans	-68.7	86.4	165.8	-110.7	160.7	0	0	0	108.3	Q125 Y129	Q125-L127 HydrophobicContact CG-CD1 4.29Å; Q125-L127 HydrophobicContact CG-CG 4.45Å; Q125-L127 PolarHBondContact O-N 3.48Å; L127-Y129 WeakPolarHBondContact O-CD2 3.25Å; L127-Y129 PolarHBondContact O-N 3.19Å
128	Q	24.6	Very low	30.1	Very low	165 Å²	165	144.7 Å²	144.7	77%	0.771	79%	0.786	S	S	*	*			trans	-72.5	99.5	170.7	-169.8	147.7	-8	0	0	108.9	Y126 T130	Y126-Q128 VanDerWaalsContact C-N 3.25Å; Y126-Q128 PolarHBondContact O-N 3.47Å; Q128-T130 PolarHBondContact O-N 2.72Å
129	Y	32.8	Very low	30.5	Very low	213 Å²	213	142.4 Å²	142.4	84%	0.835	78%	0.781	S	S	*	*			trans	-52.6	99.8	166.7	-76	-92.8	0	0	0	109.7	L127	L127-Y129 WeakPolarHBondContact O-CD2 3.25Å; L127-Y129 PolarHBondContact O-N 3.19Å
130	T	27.8	Very low	31.3	Very low	121 Å²	121	143.7 Å²	143.7	74%	0.742	77%	0.77	S	S	*	*			trans	-98.1	99	163.3	49.4	0	0	0	0	108	Q128 G132	Q128-T130 PolarHBondContact O-N 2.72Å; T130-G132 PolarHBondContact O-N 3.07Å
131	N	35.4	Very low	32.3	Very low	167 Å²	167	149.6 Å²	149.6	89%	0.893	77%	0.774	S	S	*	*			trans	-67.2	82.8	166.6	-155.5	2.3	0	0	0	107.7
132	G	29.2	Very low	33.3	Very low	64 Å²	64	145.3 Å²	145.3	66%	0.66	74%	0.744	S	S	*	*			trans	-102.7	95.7	-173.4	0	0	0	0	0	111.7	T130	T130-G132 PolarHBondContact O-N 3.07Å
133	K	27.9	Very low	34.6	Very low	197 Å²	197	143.4 Å²	143.4	86%	0.857	73%	0.729	S	S	*	*			trans	14.8	109.3	156.7	-70.9	178.9	176.6	177.7	0	116.4	K135	K133-K135 PolarHBondContact O-N 3.37Å
134	Y	34.3	Very low	36.4	Very low	222 Å²	222	142.8 Å²	142.8	87%	0.871	71%	0.712	S	S	*	*			trans	-41.8	94.5	159.6	-67.3	-91.8	0	0	0	112.2	H136	Y134-H136 PolarHBondContact O-N 3.37Å
135	K	28.1	Very low	38.7	Very low	202 Å²	202	136.6 Å²	136.6	88%	0.878	68%	0.683	S	S	*	*			trans	-79.2	94.1	150.9	-93.8	-172.5	174.4	-178.3	0	106.8	K133 G137	K133-K135 PolarHBondContact O-N 3.37Å; K135-G137 PolarHBondContact O-N 3.31Å
136	H	34.8	Very low	41.3	Very low	188 Å²	188	135.3 Å²	135.3	87%	0.87	67%	0.672	S	S	*	*			trans	-61.7	87	152.3	-96.1	-56.4	0	0	0	107.4	Y134	Y134-H136 PolarHBondContact O-N 3.37Å
137	G	27.3	Very low	44	Very low	67 Å²	67	133 Å²	133	69%	0.691	66%	0.662	S	S	*	*			trans	-133.9	99.7	179.2	0	0	0	0	0	108.9	K135	K135-G137 PolarHBondContact O-N 3.31Å
138	G	29.8	Very low	46.8	Very low	69 Å²	69	128.5 Å²	128.5	71%	0.711	64%	0.638	S	S	*	*			trans	94.7	101.9	177.9	0	0	0	0	0	112.5	R140	G138-R140 PolarHBondContact O-N 3.29Å
139	S	36.7	Very low	49.8	Very low	100 Å²	100	121.2 Å²	121.2	70%	0.699	61%	0.605	S	S	*	*			trans	-56.8	80.9	148.9	169.2	0	0	0	0	107.4	R141	S139-R141 PolarHBondContact O-N 3.32Å
140	R	46.1	Very low	52.6	Low	172 Å²	172	113.5 Å²	113.5	65%	0.649	59%	0.585	S	S	*	*			trans	-59.6	112.6	167.7	-117.1	177.7	173.3	174.6	-1.7	104.7	G138 L142	G138-R140 PolarHBondContact O-N 3.29Å; R140-L142 PolarHBondContact O-N 2.66Å
141	R	49.3	Very low	55.7	Low	211 Å²	211	111.1 Å²	111.1	80%	0.796	57%	0.567	S	S	*	*			trans	-52.8	110	177.3	-74.9	-178.3	175.9	-174.5	-0.3	107.5	S139 D143	S139-R141 PolarHBondContact O-N 3.32Å; R141-D143 PolarHBondContact O-N 3.43Å
142	L	60.8	Low	58.4	Low	31 Å²	31	103.1 Å²	103.1	16%	0.162	53%	0.525	C	S	.	.			trans	-72	87.2	163	-72.9	161.1	0	0	0	104.9	R140 V389 V393	R140-L142 PolarHBondContact O-N 2.66Å; L142-V389 HydrophobicContact CD2-CB 4.15Å; L142-V389 HydrophobicContact CD2-CG1 3.74Å; L142-V389 HydrophobicContact CD2-CG2 3.96Å; L142-V393 HydrophobicContact CD1-CG1 4.34Å; L142-V393 HydrophobicContact CD1-CG2 4.35Å
143	D	59.3	Low	61.5	Low	110 Å²	110	101.6 Å²	101.6	59%	0.588	51%	0.506	S	S	*	.			trans	-63	126.5	179.8	-70.7	-35	0	0	0	108.4	R141 E145	R141-D143 PolarHBondContact O-N 3.43Å; D143-E145 PolarHBondContact O-N 2.94Å
144	P	64.4	Low	64.6	Low	56 Å²	56	97.6 Å²	97.6	36%	0.364	49%	0.493	S	S	.	.			trans	-70.4	99.4	-176.5	26.2	-32.2	0	0	0	109.7	Y146 S223	P144-Y146 VanDerWaalsContact C-N 3.26Å; P144-Y146 HydrophobicContact CB-CD2 4.23Å; P144-Y146 HydrophobicContact CB-CE1 4.14Å; P144-Y146 HydrophobicContact CB-CE2 3.66Å; P144-Y146 HydrophobicContact CG-CD2 4.45Å; P144-Y146 HydrophobicContact CG-CE2 3.63Å; P144-Y146 WeakPolarHBondContact O-CD2 3.31Å; P144-Y146 PolarHBondContact O-N 2.89Å; P144-S223 WeakPolarHBondContact CB-OG 3.4Å
145	E	78.1	Confident	67.5	Low	38 Å²	38	89.5 Å²	89.5	18%	0.178	46%	0.461	C	S	.	.			trans	-77.1	78.5	173.9	-60.3	-175.7	122.1	0	0	110.4	D143 W147 K148 T149 R227 N388	D143-E145 PolarHBondContact O-N 2.94Å; E145-W147 PolarHBondContact O-N 3.48Å; E145-K148 HydrophobicContact CB-CB 4.3Å; E145-K148 HydrophobicContact CB-CD 4.42Å; E145-K148 HydrophobicContact CB-CG 4.22Å; E145-K148 PolarHBondContact O-N 3.33Å; E145-K148 WeakPolarHBondContact OE1-CE 3.22Å; E145-K148 IonicContact OE1-NZ 2.75Å; E145-K148 PolarHBondContact OE1-NZ 2.92Å; E145-K148 WeakPolarHBondContact OE2-CD 3.44Å; E145-K148 WeakPolarHBondContact OE2-CE 3.35Å; E145-K148 IonicContact OE2-NZ 3.45Å; E145-K148 PolarHBondContact OE2-NZ 3.41Å; E145-T149 PolarHBondContact O-N 3.47Å; E145-T149 PolarHBondContact O-OG1 3.37Å; E145-T149 VanDerWaalsContact O-OG1 3.06Å; E145-R227 IonicContact OE2-NH1 3.86Å; E145-R227 PolarHBondContact OE2-NH1 3.3Å; E145-N388 PolarHBondContact OE1-ND2 3.47Å
146	Y	83.6	Confident	70.6	Confident	142 Å²	142	80.4 Å²	80.4	56%	0.557	42%	0.422	S	S	*	.	H	α-helix	trans	-58.4	-33.3	-178	-65.9	-72.1	0	0	0	112.7	P144 T149 A150	P144-Y146 VanDerWaalsContact C-N 3.26Å; P144-Y146 HydrophobicContact CB-CD2 4.23Å; P144-Y146 HydrophobicContact CB-CE1 4.14Å; P144-Y146 HydrophobicContact CB-CE2 3.66Å; P144-Y146 HydrophobicContact CG-CD2 4.45Å; P144-Y146 HydrophobicContact CG-CE2 3.63Å; P144-Y146 WeakPolarHBondContact O-CD2 3.31Å; P144-Y146 PolarHBondContact O-N 2.89Å; Y146-T149 WeakPolarHBondContact O-CB 3.45Å; Y146-T149 PolarHBondContact O-N 3.33Å; Y146-A150 WeakPolarHBondContact O-CB 3.3Å; Y146-A150 PolarHBondContact O-N 2.84Å
147	W	85.1	Confident	73.4	Confident	151 Å²	151	75 Å²	75	57%	0.572	40%	0.402	S	S	*	.	H	α-helix	trans	-64.6	-41.6	178.8	89.6	-94.3	0	0	0	112.6	E145 T149 A150 L151 F384	E145-W147 PolarHBondContact O-N 3.48Å; W147-T149 VanDerWaalsContact C-N 3.29Å; W147-T149 PolarHBondContact O-N 2.91Å; W147-A150 PolarHBondContact O-N 3.44Å; W147-L151 HydrophobicContact CZ3-CD2 3.96Å; W147-L151 PolarHBondContact O-N 3.45Å; W147-F384 HydrophobicContact CH2-CE1 4.47Å; W147-F384 HydrophobicContact CH2-CE2 4.09Å; W147-F384 AromaticContact CH2-CZ 3.47Å; W147-F384 HydrophobicContact CH2-CZ 3.47Å; W147-F384 VanDerWaalsContact CH2-CZ 3.47Å; W147-F384 HydrophobicContact CZ2-CZ 4.16Å; W147-F384 HydrophobicContact CZ3-CZ 4.07Å
148	K	86.9	Confident	76.6	Confident	13 Å²	13	77.9 Å²	77.9	6%	0.057	40%	0.396	C	S	.	.	H	α-helix	trans	-68.1	-34.4	175.7	-64	-165.6	-166.5	159.7	0	111.4	E145 L151 S152 F385 N388	E145-K148 HydrophobicContact CB-CB 4.3Å; E145-K148 HydrophobicContact CB-CD 4.42Å; E145-K148 HydrophobicContact CB-CG 4.22Å; E145-K148 PolarHBondContact O-N 3.33Å; E145-K148 WeakPolarHBondContact OE1-CE 3.22Å; E145-K148 IonicContact OE1-NZ 2.75Å; E145-K148 PolarHBondContact OE1-NZ 2.92Å; E145-K148 WeakPolarHBondContact OE2-CD 3.44Å; E145-K148 WeakPolarHBondContact OE2-CE 3.35Å; E145-K148 IonicContact OE2-NZ 3.45Å; E145-K148 PolarHBondContact OE2-NZ 3.41Å; K148-L151 PolarHBondContact O-N 3.32Å; K148-S152 WeakPolarHBondContact O-CB 3.46Å; K148-S152 PolarHBondContact O-N 2.88Å; K148-F385 HydrophobicContact CB-CD1 4.3Å; K148-F385 WeakPolarHBondContact O-CE1 3.49Å; K148-N388 PolarHBondContact NZ-ND2 3.38Å
149	T	89	Confident	79.8	Confident	12 Å²	12	74.6 Å²	74.6	7%	0.074	36%	0.362	C	S	.	.	H	α-helix	trans	-65.3	-44.9	174.8	-49.4	0	0	0	0	110.4	E145 Y146 W147 L151 S152 A153 S223 L226 R227	E145-T149 PolarHBondContact O-N 3.47Å; E145-T149 PolarHBondContact O-OG1 3.37Å; E145-T149 VanDerWaalsContact O-OG1 3.06Å; Y146-T149 WeakPolarHBondContact O-CB 3.45Å; Y146-T149 PolarHBondContact O-N 3.33Å; W147-T149 VanDerWaalsContact C-N 3.29Å; W147-T149 PolarHBondContact O-N 2.91Å; T149-L151 PolarHBondContact O-N 2.99Å; T149-S152 PolarHBondContact O-N 2.75Å; T149-A153 WeakPolarHBondContact O-CB 3.42Å; T149-A153 PolarHBondContact O-N 3.2Å; T149-S223 WeakPolarHBondContact CG2-O 3.41Å; T149-S223 PolarHBondContact OG1-O 3.26Å; T149-L226 HydrophobicContact CG2-CB 4.25Å; T149-L226 HydrophobicContact CG2-CD2 4.03Å; T149-L226 HydrophobicContact CG2-CG 4.24Å; T149-R227 HydrophobicContact CG2-CB 4.31Å
150	A	91.1	Very high	82.4	Confident	50 Å²	50	72.7 Å²	72.7	41%	0.413	34%	0.341	S	S	.	.	H	α-helix	trans	-61.4	-43.8	175.4	0	0	0	0	0	111.7	Y146 W147 S152 A153 I154	Y146-A150 WeakPolarHBondContact O-CB 3.3Å; Y146-A150 PolarHBondContact O-N 2.84Å; W147-A150 PolarHBondContact O-N 3.44Å; A150-S152 VanDerWaalsContact C-N 3.34Å; A150-S152 PolarHBondContact O-N 2.63Å; A150-A153 WeakPolarHBondContact O-CB 3.27Å; A150-A153 PolarHBondContact O-N 3.23Å; A150-I154 VanDerWaalsContact O-CG1 3.31Å; A150-I154 WeakPolarHBondContact O-CG1 3.42Å; A150-I154 PolarHBondContact O-N 2.88Å
151	L	92.2	Very high	84.6	Confident	71 Å²	71	65.2 Å²	65.2	37%	0.372	32%	0.317	S	S	.	.	H	α-helix	trans	-62	-41.4	176.1	-177.6	58.8	0	0	0	112.2	W147 K148 T149 I154 Y155 F384	W147-L151 HydrophobicContact CZ3-CD2 3.96Å; W147-L151 PolarHBondContact O-N 3.45Å; K148-L151 PolarHBondContact O-N 3.32Å; T149-L151 PolarHBondContact O-N 2.99Å; L151-I154 PolarHBondContact O-N 3.27Å; L151-Y155 WeakPolarHBondContact O-CB 3.36Å; L151-Y155 PolarHBondContact O-N 3.11Å; L151-F384 HydrophobicContact CD2-CE1 3.64Å; L151-F384 HydrophobicContact CD2-CZ 3.8Å
152	S	92.4	Very high	86.7	Confident	0 Å²	0	58.7 Å²	58.7	0%	0	30%	0.295	C	S	.	.	H	α-helix	trans	-66	-37.6	175.1	-168.5	0	0	0	0	112.5	K148 T149 A150 Y155 V156 R227 C230 S231	K148-S152 WeakPolarHBondContact O-CB 3.46Å; K148-S152 PolarHBondContact O-N 2.88Å; T149-S152 PolarHBondContact O-N 2.75Å; A150-S152 VanDerWaalsContact C-N 3.34Å; A150-S152 PolarHBondContact O-N 2.63Å; S152-Y155 WeakPolarHBondContact O-CB 3.3Å; S152-Y155 PolarHBondContact O-N 3.28Å; S152-V156 PolarHBondContact O-N 3.47Å; S152-R227 PolarHBondContact OG-O 3.11Å; S152-R227 VanDerWaalsContact OG-O 3.08Å; S152-C230 WeakPolarHBondContact O-CB 3.34Å; S152-C230 VanDerWaalsContact OG-CB 3.25Å; S152-C230 WeakPolarHBondContact OG-CB 3.16Å; S152-S231 PolarHBondContact OG-N 2.98Å
153	A	93.4	Very high	88.2	Confident	32 Å²	32	57.7 Å²	57.7	26%	0.264	29%	0.29	S	S	.	.	H	α-helix	trans	-65.1	-45.1	174.3	0	0	0	0	0	111.6	T149 A150 Y155 V156 V157	T149-A153 WeakPolarHBondContact O-CB 3.42Å; T149-A153 PolarHBondContact O-N 3.2Å; A150-A153 WeakPolarHBondContact O-CB 3.27Å; A150-A153 PolarHBondContact O-N 3.23Å; A153-Y155 VanDerWaalsContact C-N 3.28Å; A153-Y155 PolarHBondContact O-N 2.99Å; A153-V156 WeakPolarHBondContact O-CG1 3.37Å; A153-V156 PolarHBondContact O-N 2.92Å; A153-V157 WeakPolarHBondContact O-CB 3.47Å; A153-V157 WeakPolarHBondContact O-CG2 3.16Å; A153-V157 PolarHBondContact O-N 3.33Å
154	I	94.4	Very high	89.6	Confident	113 Å²	113	53 Å²	53	58%	0.579	27%	0.266	S	S	*	.	H	α-helix	trans	-59.2	-43.2	174.6	-68.6	164.5	0	0	0	110.3	A150 L151 V157 F158	A150-I154 VanDerWaalsContact O-CG1 3.31Å; A150-I154 WeakPolarHBondContact O-CG1 3.42Å; A150-I154 PolarHBondContact O-N 2.88Å; L151-I154 PolarHBondContact O-N 3.27Å; I154-V157 PolarHBondContact O-N 3.4Å; I154-F158 WeakPolarHBondContact O-CB 3.4Å; I154-F158 PolarHBondContact O-N 3.31Å
155	Y	94.1	Very high	90.9	Very high	51 Å²	51	53 Å²	53	20%	0.2	26%	0.261	C	S	.	.	H	α-helix	trans	-57.3	-54.1	176.6	170.7	-113.1	0	0	0	111.7	L151 S152 A153 V157 F158 V159 G234 M238 M381	L151-Y155 WeakPolarHBondContact O-CB 3.36Å; L151-Y155 PolarHBondContact O-N 3.11Å; S152-Y155 WeakPolarHBondContact O-CB 3.3Å; S152-Y155 PolarHBondContact O-N 3.28Å; A153-Y155 VanDerWaalsContact C-N 3.28Å; A153-Y155 PolarHBondContact O-N 2.99Å; Y155-V157 VanDerWaalsContact C-N 3.32Å; Y155-V157 PolarHBondContact O-N 3.23Å; Y155-F158 WeakPolarHBondContact O-CB 3.45Å; Y155-F158 PolarHBondContact O-N 3.27Å; Y155-V159 HydrophobicContact CD2-CG2 3.98Å; Y155-V159 HydrophobicContact CE1-CG2 4.23Å; Y155-V159 HydrophobicContact CE2-CG2 3.55Å; Y155-V159 HydrophobicContact CG-CG2 4.47Å; Y155-V159 VanDerWaalsContact O-CG2 3.31Å; Y155-V159 WeakPolarHBondContact O-CG2 3.3Å; Y155-V159 PolarHBondContact O-N 2.91Å; Y155-G234 PolarHBondContact OH-O 3.5Å; Y155-M238 HydrophobicContact CE2-CE 4.38Å; Y155-M381 HydrophobicContact CD1-CE 3.74Å; Y155-M381 HydrophobicContact CD2-CE 4.1Å; Y155-M381 HydrophobicContact CE1-CE 3.68Å; Y155-M381 HydrophobicContact CE2-CE 4.07Å; Y155-M381 HydrophobicContact CG-CE 3.94Å
156	V	94.6	Very high	91.5	Very high	11 Å²	11	51.5 Å²	51.5	7%	0.067	25%	0.254	C	S	.	.	H	α-helix	trans	-65.8	-35.4	-177.9	74.7	0	0	0	0	112.4	S152 A153 V159 F160 C230 M233	S152-V156 PolarHBondContact O-N 3.47Å; A153-V156 WeakPolarHBondContact O-CG1 3.37Å; A153-V156 PolarHBondContact O-N 2.92Å; V156-V159 PolarHBondContact O-N 3.28Å; V156-F160 HydrophobicContact CG2-CD1 4.47Å; V156-F160 HydrophobicContact CG2-CD2 4.1Å; V156-F160 HydrophobicContact CG2-CE1 4.04Å; V156-F160 HydrophobicContact CG2-CE2 3.64Å; V156-F160 HydrophobicContact CG2-CZ 3.6Å; V156-F160 WeakPolarHBondContact O-CG 3.13Å; V156-F160 PolarHBondContact O-N 3.19Å; V156-C230 HydrophobicContact CB-CB 4.1Å; V156-C230 HydrophobicContact CG1-CB 3.81Å; V156-M233 HydrophobicContact CG2-CB 4.06Å
157	V	93.8	Very high	91.7	Very high	74 Å²	74	45.3 Å²	45.3	45%	0.448	23%	0.23	S	C	.	.	H	α-helix	trans	-61.8	-45.7	174.9	169.9	0	0	0	0	110.5	A153 I154 Y155 F160 G161 W277	A153-V157 WeakPolarHBondContact O-CB 3.47Å; A153-V157 WeakPolarHBondContact O-CG2 3.16Å; A153-V157 PolarHBondContact O-N 3.33Å; I154-V157 PolarHBondContact O-N 3.4Å; Y155-V157 VanDerWaalsContact C-N 3.32Å; Y155-V157 PolarHBondContact O-N 3.23Å; V157-F160 PolarHBondContact O-N 3.49Å; V157-G161 PolarHBondContact O-N 3.25Å; V157-W277 HydrophobicContact CG1-CH2 4.43Å; V157-W277 HydrophobicContact CG1-CZ2 3.7Å
158	F	94.6	Very high	91.8	Very high	129 Å²	129	38.3 Å²	38.3	57%	0.566	20%	0.204	S	C	*	.	H	α-helix	trans	-61.2	-44.8	173.6	175.1	-95.4	0	0	0	111.8	I154 Y155 F160 G161 F162	I154-F158 WeakPolarHBondContact O-CB 3.4Å; I154-F158 PolarHBondContact O-N 3.31Å; Y155-F158 WeakPolarHBondContact O-CB 3.45Å; Y155-F158 PolarHBondContact O-N 3.27Å; F158-F160 PolarHBondContact O-N 2.89Å; F158-G161 PolarHBondContact O-N 3.36Å; F158-F162 WeakPolarHBondContact O-CB 3.44Å; F158-F162 PolarHBondContact O-N 2.92Å
159	V	95.1	Very high	91.8	Very high	0 Å²	0	39.1 Å²	39.1	0%	0	21%	0.208	C	C	.	.	H	α-helix	trans	-62.2	-41.1	178.1	177.3	0	0	0	0	111.7	Y155 V156 F162 T163 F237 M238	Y155-V159 HydrophobicContact CD2-CG2 3.98Å; Y155-V159 HydrophobicContact CE1-CG2 4.23Å; Y155-V159 HydrophobicContact CE2-CG2 3.55Å; Y155-V159 HydrophobicContact CG-CG2 4.47Å; Y155-V159 VanDerWaalsContact O-CG2 3.31Å; Y155-V159 WeakPolarHBondContact O-CG2 3.3Å; Y155-V159 PolarHBondContact O-N 2.91Å; V156-V159 PolarHBondContact O-N 3.28Å; V159-F162 PolarHBondContact O-N 3.27Å; V159-T163 WeakPolarHBondContact O-CB 3.47Å; V159-T163 PolarHBondContact O-N 3.38Å; V159-T163 PolarHBondContact O-OG1 3.2Å; V159-F237 HydrophobicContact CG1-CB 3.64Å; V159-M238 HydrophobicContact CG1-CB 4.4Å; V159-M238 HydrophobicContact CG2-CE 3.61Å
160	F	92.9	Very high	91.7	Very high	60 Å²	60	38.5 Å²	38.5	26%	0.263	21%	0.205	S	C	.	.	H	α-helix	trans	-68.1	-38.7	177.1	-69.4	-24.5	0	0	0	112.8	V156 V157 F158 T163 S164 M233 F237	V156-F160 HydrophobicContact CG2-CD1 4.47Å; V156-F160 HydrophobicContact CG2-CD2 4.1Å; V156-F160 HydrophobicContact CG2-CE1 4.04Å; V156-F160 HydrophobicContact CG2-CE2 3.64Å; V156-F160 HydrophobicContact CG2-CZ 3.6Å; V156-F160 WeakPolarHBondContact O-CG 3.13Å; V156-F160 PolarHBondContact O-N 3.19Å; V157-F160 PolarHBondContact O-N 3.49Å; F158-F160 PolarHBondContact O-N 2.89Å; F160-T163 PolarHBondContact O-N 2.93Å; F160-S164 PolarHBondContact O-N 3.4Å; F160-S164 PolarHBondContact O-OG 3.21Å; F160-M233 HydrophobicContact CZ-CB 4.43Å; F160-M233 HydrophobicContact CZ-CE 4.13Å; F160-F237 HydrophobicContact CD1-CD1 4.19Å; F160-F237 HydrophobicContact CD1-CG 4.25Å; F160-F237 HydrophobicContact CE1-CB 4.4Å; F160-F237 HydrophobicContact CE1-CD1 4.05Å; F160-F237 AromaticContact CE1-CD2 3.9Å; F160-F237 HydrophobicContact CE1-CD2 3.9Å; F160-F237 HydrophobicContact CE1-CE1 4.28Å; F160-F237 HydrophobicContact CE1-CE2 4.14Å; F160-F237 AromaticContact CE1-CG 3.84Å; F160-F237 HydrophobicContact CE1-CG 3.84Å; F160-F237 HydrophobicContact CE1-CZ 4.32Å
161	G	92.1	Very high	91.4	Very high	14 Å²	14	36.9 Å²	36.9	14%	0.144	19%	0.188	C	C	.	.	H	α-helix	trans	-61.4	-46.2	170.8	0	0	0	0	0	111.8	V157 F158 T163 S164 F165	V157-G161 PolarHBondContact O-N 3.25Å; F158-G161 PolarHBondContact O-N 3.36Å; G161-T163 PolarHBondContact O-N 3.22Å; G161-S164 PolarHBondContact O-N 2.92Å; G161-F165 PolarHBondContact O-N 3.32Å
162	F	92.9	Very high	91	Very high	75 Å²	75	36 Å²	36	33%	0.329	18%	0.183	S	C	.	.	H	α-helix	trans	-62.6	-40.8	175.7	-176.9	-115.6	0	0	0	112.3	F158 V159 S164 F165 V166 M238 C241	F158-F162 WeakPolarHBondContact O-CB 3.44Å; F158-F162 PolarHBondContact O-N 2.92Å; V159-F162 PolarHBondContact O-N 3.27Å; F162-S164 VanDerWaalsContact C-N 3.35Å; F162-S164 PolarHBondContact O-N 3.32Å; F162-F165 WeakPolarHBondContact O-CB 3.49Å; F162-F165 PolarHBondContact O-N 3.17Å; F162-V166 HydrophobicContact CD1-CG2 4.22Å; F162-V166 HydrophobicContact CD2-CG2 4.32Å; F162-V166 HydrophobicContact CE1-CG2 3.81Å; F162-V166 HydrophobicContact CE2-CG2 3.91Å; F162-V166 HydrophobicContact CG-CG2 4.46Å; F162-V166 HydrophobicContact CZ-CG2 3.63Å; F162-V166 WeakPolarHBondContact O-CG2 3.34Å; F162-V166 PolarHBondContact O-N 3.38Å; F162-M238 HydrophobicContact CD1-SD 4.16Å; F162-M238 HydrophobicContact CE1-SD 4.2Å; F162-C241 HydrophobicContact CD1-CB 3.92Å; F162-C241 HydrophobicContact CE1-CB 3.64Å
163	T	91.6	Very high	90.6	Very high	10 Å²	10	41.7 Å²	41.7	6%	0.061	20%	0.204	C	C	.	.	H	α-helix	trans	-58	-49.5	174.3	-55.3	0	0	0	0	110.1	V159 F160 G161 F165 V166 M167 F237 C241	V159-T163 WeakPolarHBondContact O-CB 3.47Å; V159-T163 PolarHBondContact O-N 3.38Å; V159-T163 PolarHBondContact O-OG1 3.2Å; F160-T163 PolarHBondContact O-N 2.93Å; G161-T163 PolarHBondContact O-N 3.22Å; T163-F165 VanDerWaalsContact C-N 3.25Å; T163-F165 PolarHBondContact O-N 3.27Å; T163-V166 PolarHBondContact O-N 2.74Å; T163-V166 VanDerWaalsContact O-N 3.13Å; T163-M167 HydrophobicContact CG2-CE 4.03Å; T163-M167 HydrophobicContact CG2-CG 4.38Å; T163-M167 VanDerWaalsContact O-CG 3.29Å; T163-M167 WeakPolarHBondContact O-CG 3.36Å; T163-M167 PolarHBondContact O-N 2.88Å; T163-F237 HydrophobicContact CG2-CD1 4.04Å; T163-C241 WeakPolarHBondContact CA-SG 3.28Å; T163-C241 PolarHBondContact OG1-SG 3.47Å
164	S	90.2	Very high	90	Very high	11 Å²	11	41 Å²	41	8%	0.077	20%	0.197	C	C	.	.	H	α-helix	trans	-59.4	-38.3	179.8	-54.9	0	0	0	0	111.9	F160 G161 F162 V168 A273 W277	F160-S164 PolarHBondContact O-N 3.4Å; F160-S164 PolarHBondContact O-OG 3.21Å; G161-S164 PolarHBondContact O-N 2.92Å; F162-S164 VanDerWaalsContact C-N 3.35Å; F162-S164 PolarHBondContact O-N 3.32Å; S164-V168 WeakPolarHBondContact O-CG2 3.44Å; S164-V168 PolarHBondContact O-N 2.6Å; S164-A273 WeakPolarHBondContact CB-O 3.38Å; S164-W277 WeakPolarHBondContact OG-CA 3.24Å
165	F	90.3	Very high	89.4	Confident	57 Å²	57	37.4 Å²	37.4	25%	0.25	18%	0.181	C	C	.	.	H	α-helix	trans	-67.5	-45.5	174	-179.5	-107.3	0	0	0	112.8	G161 F162 T163 M167 V168 I169 M266 A273	G161-F165 PolarHBondContact O-N 3.32Å; F162-F165 WeakPolarHBondContact O-CB 3.49Å; F162-F165 PolarHBondContact O-N 3.17Å; T163-F165 VanDerWaalsContact C-N 3.25Å; T163-F165 PolarHBondContact O-N 3.27Å; F165-M167 VanDerWaalsContact C-N 3.3Å; F165-M167 PolarHBondContact O-N 2.91Å; F165-V168 PolarHBondContact O-N 3.17Å; F165-I169 HydrophobicContact CD1-CD1 3.83Å; F165-I169 HydrophobicContact CE1-CD1 3.29Å; F165-I169 HydrophobicContact CE1-CG1 4.32Å; F165-I169 HydrophobicContact CE2-CD1 4.41Å; F165-I169 HydrophobicContact CZ-CD1 3.63Å; F165-I169 HydrophobicContact CZ-CG1 4.35Å; F165-I169 PolarHBondContact O-N 3.38Å; F165-I169 VanDerWaalsContact O-N 3.14Å; F165-M266 HydrophobicContact CE2-SD 4.39Å; F165-M266 HydrophobicContact CZ-SD 4.43Å; F165-A273 HydrophobicContact CB-CB 4.3Å; F165-A273 HydrophobicContact CD2-CB 4.41Å
166	V	90.4	Very high	88.7	Confident	5 Å²	5	39.7 Å²	39.7	3%	0.03	20%	0.196	C	C	.	.	H	α-helix	trans	-62.1	-38.5	176.5	171.9	0	0	0	0	111.1	F162 T163 V168 I169 V170 C241 F245	F162-V166 HydrophobicContact CD1-CG2 4.22Å; F162-V166 HydrophobicContact CD2-CG2 4.32Å; F162-V166 HydrophobicContact CE1-CG2 3.81Å; F162-V166 HydrophobicContact CE2-CG2 3.91Å; F162-V166 HydrophobicContact CG-CG2 4.46Å; F162-V166 HydrophobicContact CZ-CG2 3.63Å; F162-V166 WeakPolarHBondContact O-CG2 3.34Å; F162-V166 PolarHBondContact O-N 3.38Å; T163-V166 PolarHBondContact O-N 2.74Å; T163-V166 VanDerWaalsContact O-N 3.13Å; V166-V168 VanDerWaalsContact C-N 3.31Å; V166-V168 PolarHBondContact O-N 2.98Å; V166-I169 PolarHBondContact O-N 3.46Å; V166-I169 VanDerWaalsContact O-N 3.16Å; V166-V170 HydrophobicContact CG1-CG2 3.89Å; V166-V170 WeakPolarHBondContact O-CB 3.4Å; V166-V170 VanDerWaalsContact O-CG2 3.29Å; V166-V170 WeakPolarHBondContact O-CG2 3.38Å; V166-V170 PolarHBondContact O-N 2.89Å; V166-C241 HydrophobicContact CG1-CB 4.49Å; V166-C241 HydrophobicContact CG2-CB 4.23Å; V166-F245 HydrophobicContact CG1-CB 4.43Å
167	M	88	Confident	88	Confident	13 Å²	13	41.9 Å²	41.9	6%	0.064	21%	0.207	C	C	.	.	H	α-helix	trans	-57.1	-43.3	174.2	-68.5	-49.2	-166.5	0	0	112	T163 F165 V170 H171 M244 D292	T163-M167 HydrophobicContact CG2-CE 4.03Å; T163-M167 HydrophobicContact CG2-CG 4.38Å; T163-M167 VanDerWaalsContact O-CG 3.29Å; T163-M167 WeakPolarHBondContact O-CG 3.36Å; T163-M167 PolarHBondContact O-N 2.88Å; F165-M167 VanDerWaalsContact C-N 3.3Å; F165-M167 PolarHBondContact O-N 2.91Å; M167-V170 PolarHBondContact O-N 2.89Å; M167-H171 VanDerWaalsContact O-CB 3.23Å; M167-H171 WeakPolarHBondContact O-CB 3.49Å; M167-H171 PolarHBondContact O-N 2.94Å; M167-M244 HydrophobicContact CE-CE 4.1Å; M167-M244 HydrophobicContact CE-SD 3.76Å; M167-M244 HydrophobicContact SD-SD 3.72Å; M167-D292 HydrophobicContact CE-CB 3.49Å; M167-D292 VanDerWaalsContact CE-CB 3.49Å; M167-D292 HydrophobicContact SD-CB 3.29Å; M167-D292 WeakPolarHBondContact SD-CB 3.18Å
168	V	87.4	Confident	87.4	Confident	3 Å²	3	49.6 Å²	49.6	2%	0.018	23%	0.228	C	C	.	.	H	α-helix	trans	-64	-42	177	175.8	0	0	0	0	111.3	S164 F165 V166 H171 E172 K269 R272 A273 I276	S164-V168 WeakPolarHBondContact O-CG2 3.44Å; S164-V168 PolarHBondContact O-N 2.6Å; F165-V168 PolarHBondContact O-N 3.17Å; V166-V168 VanDerWaalsContact C-N 3.31Å; V166-V168 PolarHBondContact O-N 2.98Å; V168-H171 WeakPolarHBondContact O-CB 3.31Å; V168-E172 PolarHBondContact O-N 3.39Å; V168-K269 HydrophobicContact CG1-CB 3.98Å; V168-K269 HydrophobicContact CG1-CG 4.18Å; V168-R272 HydrophobicContact CG2-CB 4.38Å; V168-R272 HydrophobicContact CG2-CG 4.18Å; V168-A273 HydrophobicContact CG2-CB 4.06Å; V168-I276 HydrophobicContact CG2-CD1 3.49Å; V168-I276 VanDerWaalsContact CG2-CD1 3.49Å
169	I	87.6	Confident	86.9	Confident	30 Å²	30	47.7 Å²	47.7	15%	0.154	23%	0.227	C	C	.	.	H	α-helix	trans	-64.9	-47.8	177.9	-68.5	175.7	0	0	0	111.1	F165 V166 H171 E172 R173 F245	F165-I169 HydrophobicContact CD1-CD1 3.83Å; F165-I169 HydrophobicContact CE1-CD1 3.29Å; F165-I169 HydrophobicContact CE1-CG1 4.32Å; F165-I169 HydrophobicContact CE2-CD1 4.41Å; F165-I169 HydrophobicContact CZ-CD1 3.63Å; F165-I169 HydrophobicContact CZ-CG1 4.35Å; F165-I169 PolarHBondContact O-N 3.38Å; F165-I169 VanDerWaalsContact O-N 3.14Å; V166-I169 PolarHBondContact O-N 3.46Å; V166-I169 VanDerWaalsContact O-N 3.16Å; I169-H171 VanDerWaalsContact C-N 3.26Å; I169-H171 PolarHBondContact O-N 3.49Å; I169-E172 PolarHBondContact O-N 3.27Å; I169-R173 VanDerWaalsContact CG2-CZ 3.49Å; I169-R173 PolarHBondContact O-N 3.46Å; I169-F245 HydrophobicContact CG2-CE2 4.46Å
170	V	86.8	Confident	86.3	Confident	0 Å²	0	54.3 Å²	54.3	0%	0	25%	0.253	C	S	.	.	H	α-helix	trans	-66.3	-34.4	-177.4	173.5	0	0	0	0	110.3	V166 M167 E172 R173 V174 M244 G291	V166-V170 HydrophobicContact CG1-CG2 3.89Å; V166-V170 WeakPolarHBondContact O-CB 3.4Å; V166-V170 VanDerWaalsContact O-CG2 3.29Å; V166-V170 WeakPolarHBondContact O-CG2 3.38Å; V166-V170 PolarHBondContact O-N 2.89Å; M167-V170 PolarHBondContact O-N 2.89Å; V170-E172 VanDerWaalsContact C-N 3.3Å; V170-E172 PolarHBondContact O-N 3.48Å; V170-R173 CarbonylContact O-C 3.5Å; V170-R173 WeakPolarHBondContact O-CA 3.39Å; V170-R173 PolarHBondContact O-N 3.24Å; V170-V174 WeakPolarHBondContact O-CG2 3.27Å; V170-V174 PolarHBondContact O-N 3.24Å; V170-V174 VanDerWaalsContact O-N 3.07Å; V170-M244 HydrophobicContact CG2-CB 4.17Å; V170-M244 WeakPolarHBondContact CG2-O 3.23Å; V170-G291 WeakPolarHBondContact CG1-O 3.37Å
171	H	85.1	Confident	85.9	Confident	15 Å²	15	55.9 Å²	55.9	7%	0.069	27%	0.268	C	S	.	.	H	α-helix	trans	-56.5	-39.8	173.1	-174.5	67.2	0	0	0	113.7	M167 V168 I169 R173 V174 C290	M167-H171 VanDerWaalsContact O-CB 3.23Å; M167-H171 WeakPolarHBondContact O-CB 3.49Å; M167-H171 PolarHBondContact O-N 2.94Å; V168-H171 WeakPolarHBondContact O-CB 3.31Å; I169-H171 VanDerWaalsContact C-N 3.26Å; I169-H171 PolarHBondContact O-N 3.49Å; H171-R173 VanDerWaalsContact C-N 3.32Å; H171-V174 WeakPolarHBondContact O-CG2 3.46Å; H171-C290 WeakPolarHBondContact CA-O 3.5Å; H171-C290 VanDerWaalsContact CB-O 3.31Å; H171-C290 WeakPolarHBondContact CB-O 3.25Å; H171-C290 WeakPolarHBondContact ND1-CA 3.44Å; H171-C290 VanDerWaalsContact ND1-CB 3.27Å; H171-C290 WeakPolarHBondContact ND1-CB 3.44Å; H171-C290 PolarHBondContact ND1-N 3.06Å; H171-C290 PolarHBondContact ND1-O 3.11Å; H171-C290 VanDerWaalsContact ND1-O 3.14Å
172	E	83.1	Confident	85.7	Confident	53 Å²	53	57.6 Å²	57.6	25%	0.248	28%	0.277	C	S	.	.	H	α-helix	trans	-74.6	-24.1	175.7	-66.8	-179.7	170.3	0	0	113.1	V168 I169 V170 V174 K269	V168-E172 PolarHBondContact O-N 3.39Å; I169-E172 PolarHBondContact O-N 3.27Å; V170-E172 VanDerWaalsContact C-N 3.3Å; V170-E172 PolarHBondContact O-N 3.48Å; E172-V174 VanDerWaalsContact C-N 3.34Å; E172-K269 VanDerWaalsContact CD-NZ 3.32Å; E172-K269 WeakPolarHBondContact OE1-CE 3.39Å; E172-K269 IonicContact OE1-NZ 2.65Å; E172-K269 PolarHBondContact OE1-NZ 3.14Å; E172-K269 WeakPolarHBondContact OE2-CE 3.12Å; E172-K269 IonicContact OE2-NZ 3.79Å; E172-K269 PolarHBondContact OE2-NZ 3.3Å
173	R	83.3	Confident	85.5	Confident	119 Å²	119	58.3 Å²	58.3	45%	0.449	28%	0.284	S	S	.	.	H	α-helix	trans	-88	-2.2	177.3	-67.2	-170.6	-174.2	139.7	0.9	113.6	I169 V170 H171 P175	I169-R173 VanDerWaalsContact CG2-CZ 3.49Å; I169-R173 PolarHBondContact O-N 3.46Å; V170-R173 CarbonylContact O-C 3.5Å; V170-R173 WeakPolarHBondContact O-CA 3.39Å; V170-R173 PolarHBondContact O-N 3.24Å; H171-R173 VanDerWaalsContact C-N 3.32Å; R173-P175 WeakPolarHBondContact O-CD 3.09Å
174	V	82.5	Confident	85.4	Confident	19 Å²	19	63.6 Å²	63.6	12%	0.115	32%	0.319	C	S	.	.	P	Polyproline II helix	trans	-56.6	125.3	177.2	174.2	0	0	0	0	109	V170 H171 E172 V251 C290	V170-V174 WeakPolarHBondContact O-CG2 3.27Å; V170-V174 PolarHBondContact O-N 3.24Å; V170-V174 VanDerWaalsContact O-N 3.07Å; H171-V174 WeakPolarHBondContact O-CG2 3.46Å; E172-V174 VanDerWaalsContact C-N 3.34Å; V174-V251 HydrophobicContact CG1-CG2 3.64Å; V174-C290 HydrophobicContact CG2-CB 4.31Å
175	P	80.6	Confident	85.4	Confident	37 Å²	37	64 Å²	64	24%	0.24	32%	0.32	C	S	.	.	P	Polyproline II helix	trans	-57.6	145.7	176.4	-23.2	32.5	0	0	0	111.6	R173 M177 Y180	R173-P175 WeakPolarHBondContact O-CD 3.09Å; P175-M177 PolarHBondContact O-N 2.92Å; P175-Y180 HydrophobicContact CB-CD2 3.53Å; P175-Y180 HydrophobicContact CB-CE2 4.22Å; P175-Y180 HydrophobicContact CB-CG 3.95Å
176	D	80	Confident	85.5	Confident	98 Å²	98	68 Å²	68	52%	0.524	34%	0.342	S	S	.	.	P	Polyproline II helix	trans	-60.4	124.2	177.7	-172.1	-4.2	0	0	0	110.5	R178 T179 Y180	D176-R178 PolarHBondContact O-N 3.31Å; D176-R178 VanDerWaalsContact O-N 3.14Å; D176-R178 PolarHBondContact OD1-N 3.22Å; D176-T179 PolarHBondContact O-N 2.95Å; D176-Y180 PolarHBondContact O-N 3.4Å
177	M	80.1	Confident	85.5	Confident	58 Å²	58	70.5 Å²	70.5	29%	0.286	35%	0.353	S	S	.	.	T	Hydrogen-bonded Turn	trans	-60.9	-23.9	-176.4	-61.4	172.4	71.9	0	0	112.7	P175 V251 L256 C258	P175-M177 PolarHBondContact O-N 2.92Å; M177-V251 HydrophobicContact CE-CB 4.15Å; M177-V251 HydrophobicContact CE-CG1 4.01Å; M177-V251 HydrophobicContact CG-CB 4.31Å; M177-V251 HydrophobicContact CG-CG2 3.99Å; M177-V251 HydrophobicContact SD-CB 4.48Å; M177-V251 HydrophobicContact SD-CG2 4.2Å; M177-L256 WeakPolarHBondContact CE-O 3.33Å; M177-C258 HydrophobicContact SD-CB 4.33Å
178	R	80	Confident	85.5	Confident	236 Å²	236	70.8 Å²	70.8	89%	0.891	36%	0.355	S	S	*	.	T	Hydrogen-bonded Turn	trans	-74.1	-34.2	176.9	-66.6	-176.6	176.3	-178.8	-0.1	112.8	D176	D176-R178 PolarHBondContact O-N 3.31Å; D176-R178 VanDerWaalsContact O-N 3.14Å; D176-R178 PolarHBondContact OD1-N 3.22Å
179	T	84.6	Confident	85.5	Confident	89 Å²	89	76.5 Å²	76.5	55%	0.546	39%	0.385	S	S	.	.	T	Hydrogen-bonded Turn	trans	-90	-35.4	-176.8	-53.1	0	0	0	0	111	D176	D176-T179 PolarHBondContact O-N 2.95Å
180	Y	83.1	Confident	85.7	Confident	139 Å²	139	79.4 Å²	79.4	55%	0.545	41%	0.408	S	S	.	.	S	Bend	trans	-122.7	97.5	-175.8	-60.2	-80.1	0	0	0	110.4	P175 D176	P175-Y180 HydrophobicContact CB-CD2 3.53Å; P175-Y180 HydrophobicContact CB-CE2 4.22Å; P175-Y180 HydrophobicContact CB-CG 3.95Å; D176-Y180 PolarHBondContact O-N 3.4Å
181	P	84.6	Confident	85.8	Confident	92 Å²	92	81.2 Å²	81.2	60%	0.597	42%	0.419	S	S	*	.	P	Polyproline II helix	trans	-67.3	168.4	176.9	28.2	-34	0	0	0	112.3	S250	P181-S250 PolarHBondContact O-OG 2.74Å
182	P	86.8	Confident	86.1	Confident	51 Å²	51	85.5 Å²	85.5	33%	0.331	45%	0.448	S	S	.	.	P	Polyproline II helix	trans	-55.3	144.8	172.5	-21.2	31.1	0	0	0	111.5	V251	P182-V251 WeakPolarHBondContact CB-O 3.36Å; P182-V251 WeakPolarHBondContact CG-O 3.47Å
183	L	88.7	Confident	86.5	Confident	89 Å²	89	87.9 Å²	87.9	47%	0.466	46%	0.455	S	S	.	.	P	Polyproline II helix	trans	-69.2	147	173.4	-84.7	69.5	0	0	0	110.1	D185 S250 Y342	L183-D185 PolarHBondContact O-N 2.87Å; L183-S250 WeakPolarHBondContact CD1-OG 3.34Å; L183-Y342 HydrophobicContact CB-CE1 3.94Å; L183-Y342 PolarHBondContact N-OH 3.29Å; L183-Y342 VanDerWaalsContact N-OH 3.15Å
184	P	89.2	Confident	86.9	Confident	122 Å²	122	84.2 Å²	84.2	79%	0.792	44%	0.444	S	S	*	.	P	Polyproline II helix	trans	-63.9	128.4	176.4	27.1	-33.8	0	0	0	110.2
185	D	91	Very high	87.2	Confident	18 Å²	18	87.9 Å²	87.9	10%	0.096	47%	0.468	C	S	.	.			trans	-142.7	114.1	-178.3	-175.3	-41.3	0	0	0	109.4	L183 F187 L188 D189 Y342 S343	L183-D185 PolarHBondContact O-N 2.87Å; D185-F187 PolarHBondContact O-N 3.4Å; D185-F187 VanDerWaalsContact O-N 3.11Å; D185-F187 PolarHBondContact OD1-N 3.4Å; D185-L188 HydrophobicContact CB-CB 4.06Å; D185-L188 HydrophobicContact CB-CD1 3.7Å; D185-L188 HydrophobicContact CB-CG 4.13Å; D185-L188 PolarHBondContact O-N 2.8Å; D185-L188 VanDerWaalsContact O-N 3.08Å; D185-D189 WeakPolarHBondContact O-CB 3.42Å; D185-D189 VanDerWaalsContact O-CG 3.23Å; D185-D189 PolarHBondContact O-N 2.9Å; D185-Y342 HydrophobicContact CB-CD1 4.24Å; D185-S343 VanDerWaalsContact CG-OG 3.28Å; D185-S343 WeakPolarHBondContact OD1-CB 3.48Å; D185-S343 PolarHBondContact OD1-OG 3.07Å; D185-S343 VanDerWaalsContact OD2-CB 3.26Å; D185-S343 WeakPolarHBondContact OD2-CB 3.38Å; D185-S343 PolarHBondContact OD2-N 3.36Å; D185-S343 PolarHBondContact OD2-OG 2.62Å; D185-S343 VanDerWaalsContact OD2-OG 3.13Å
186	I	91.9	Very high	87.7	Confident	142 Å²	142	93.2 Å²	93.2	73%	0.728	48%	0.483	S	S	*	.	H	α-helix	trans	-54.2	-38.4	-171.9	-62.4	169.5	0	0	0	111.9	S190	I186-S190 WeakPolarHBondContact O-CB 3.33Å; I186-S190 PolarHBondContact O-N 2.83Å; I186-S190 VanDerWaalsContact O-N 3.09Å; I186-S190 PolarHBondContact O-OG 2.91Å
187	F	90.9	Very high	88.3	Confident	58 Å²	58	88.5 Å²	88.5	25%	0.254	46%	0.458	S	S	.	.	H	α-helix	trans	-72.8	-46	-178.6	-172.7	-84.4	0	0	0	111.2	D185 D189 S190 V191 F333 L336 S343	D185-F187 PolarHBondContact O-N 3.4Å; D185-F187 VanDerWaalsContact O-N 3.11Å; D185-F187 PolarHBondContact OD1-N 3.4Å; F187-D189 PolarHBondContact O-N 2.82Å; F187-S190 PolarHBondContact O-N 3.28Å; F187-S190 VanDerWaalsContact O-N 3.12Å; F187-V191 HydrophobicContact CD1-CB 4.34Å; F187-V191 HydrophobicContact CD1-CG2 4.21Å; F187-V191 HydrophobicContact CD2-CG2 4.31Å; F187-V191 HydrophobicContact CE1-CB 3.97Å; F187-V191 HydrophobicContact CE1-CG1 4.25Å; F187-V191 HydrophobicContact CE1-CG2 3.86Å; F187-V191 HydrophobicContact CE2-CG2 4Å; F187-V191 HydrophobicContact CG-CG2 4.42Å; F187-V191 HydrophobicContact CZ-CB 4.32Å; F187-V191 HydrophobicContact CZ-CG1 4.46Å; F187-V191 HydrophobicContact CZ-CG2 3.77Å; F187-V191 PolarHBondContact O-N 3.33Å; F187-F333 HydrophobicContact CZ-CD2 4.47Å; F187-F333 HydrophobicContact CZ-CE2 4.4Å; F187-L336 HydrophobicContact CD1-CB 3.88Å; F187-L336 HydrophobicContact CE1-CB 3.38Å; F187-L336 HydrophobicContact CE1-CD1 4.36Å; F187-L336 HydrophobicContact CE1-CG 4.41Å; F187-L336 HydrophobicContact CE2-CD1 4.29Å; F187-L336 HydrophobicContact CZ-CB 3.81Å; F187-L336 HydrophobicContact CZ-CD1 4.19Å; F187-S343 WeakPolarHBondContact CB-OG 3.42Å
188	L	88.1	Confident	88.8	Confident	19 Å²	19	86.4 Å²	86.4	10%	0.099	45%	0.447	C	S	.	.	H	α-helix	trans	-64.1	-30.9	179.4	-68.5	167.5	0	0	0	111.4	D185 P252 H339 Y342	D185-L188 HydrophobicContact CB-CB 4.06Å; D185-L188 HydrophobicContact CB-CD1 3.7Å; D185-L188 HydrophobicContact CB-CG 4.13Å; D185-L188 PolarHBondContact O-N 2.8Å; D185-L188 VanDerWaalsContact O-N 3.08Å; L188-P252 HydrophobicContact CD1-CB 4.28Å; L188-H339 HydrophobicContact CD2-CB 3.62Å; L188-H339 PolarHBondContact O-CE1 3.08Å; L188-Y342 HydrophobicContact CD1-CD1 3.8Å; L188-Y342 HydrophobicContact CD1-CE1 4.34Å
189	D	88.6	Confident	89.4	Confident	123 Å²	123	76.8 Å²	76.8	66%	0.658	42%	0.419	S	S	*	.	H	α-helix	trans	-77.7	-28.1	175.7	-65	-28.9	0	0	0	112.5	D185 F187	D185-D189 WeakPolarHBondContact O-CB 3.42Å; D185-D189 VanDerWaalsContact O-CG 3.23Å; D185-D189 PolarHBondContact O-N 2.9Å; F187-D189 PolarHBondContact O-N 2.82Å
190	S	90.7	Very high	89.9	Confident	91 Å²	91	76.6 Å²	76.6	64%	0.636	41%	0.412	S	S	*	.	H	α-helix	trans	-92.9	-28	-175.1	-59.4	0	0	0	0	114.2	I186 F187	I186-S190 WeakPolarHBondContact O-CB 3.33Å; I186-S190 PolarHBondContact O-N 2.83Å; I186-S190 VanDerWaalsContact O-N 3.09Å; I186-S190 PolarHBondContact O-OG 2.91Å; F187-S190 PolarHBondContact O-N 3.28Å; F187-S190 VanDerWaalsContact O-N 3.12Å
191	V	90.1	Very high	90.4	Very high	38 Å²	38	70 Å²	70	23%	0.23	39%	0.386	C	S	.	.	S	Bend	trans	-108.3	130.9	-174.8	179.1	0	0	0	0	109.4	F187 H339	F187-V191 HydrophobicContact CD1-CB 4.34Å; F187-V191 HydrophobicContact CD1-CG2 4.21Å; F187-V191 HydrophobicContact CD2-CG2 4.31Å; F187-V191 HydrophobicContact CE1-CB 3.97Å; F187-V191 HydrophobicContact CE1-CG1 4.25Å; F187-V191 HydrophobicContact CE1-CG2 3.86Å; F187-V191 HydrophobicContact CE2-CG2 4Å; F187-V191 HydrophobicContact CG-CG2 4.42Å; F187-V191 HydrophobicContact CZ-CB 4.32Å; F187-V191 HydrophobicContact CZ-CG1 4.46Å; F187-V191 HydrophobicContact CZ-CG2 3.77Å; F187-V191 PolarHBondContact O-N 3.33Å; V191-H339 PolarHBondContact O-CE1 3.11Å; V191-H339 PolarHBondContact O-NE2 3.06Å
192	P	90.3	Very high	90.9	Very high	104 Å²	104	65.8 Å²	65.8	68%	0.675	36%	0.359	S	S	*	.			trans	-71.3	141.8	174.3	29.3	-33.9	0	0	0	110.8	I194	P192-I194 PolarHBondContact O-N 3.36Å
193	R	90.8	Very high	91.2	Very high	104 Å²	104	64.9 Å²	64.9	39%	0.392	36%	0.356	S	S	.	.			trans	-60.6	133	178	-178.8	-175.9	174.2	-135.3	-2.8	111.8	H255 A338 H339	R193-H255 VanDerWaalsContact CZ-NE2 3.33Å; R193-H255 PolarHBondContact NE-CD2 3.29Å; R193-H255 PolarHBondContact NE-CE1 3.3Å; R193-H255 VanDerWaalsContact NE-CE1 3.26Å; R193-H255 PolarHBondContact NE-ND1 3.15Å; R193-H255 PolarHBondContact NE-NE2 2.94Å; R193-H255 PolarHBondContact NH1-CD2 3.49Å; R193-H255 PolarHBondContact NH2-CD2 3.45Å; R193-H255 PolarHBondContact NH2-NE2 3.31Å; R193-A338 PolarHBondContact NE-O 3.41Å; R193-H339 HydrophobicContact CB-CB 4.48Å; R193-H339 HydrophobicContact CG-CB 4.19Å
194	I	92.5	Very high	91.6	Very high	42 Å²	42	61.2 Å²	61.2	22%	0.215	34%	0.338	C	S	.	.			trans	-110.8	110.5	172.8	-62.4	172	0	0	0	109.3	P192 W196 A197 A337	P192-I194 PolarHBondContact O-N 3.36Å; I194-W196 VanDerWaalsContact C-N 3.34Å; I194-W196 HydrophobicContact CG2-CD2 3.52Å; I194-W196 HydrophobicContact CG2-CE3 4.09Å; I194-W196 HydrophobicContact CG2-CG 3.91Å; I194-W196 HydrophobicContact CG2-CH2 4.11Å; I194-W196 HydrophobicContact CG2-CZ2 3.54Å; I194-W196 HydrophobicContact CG2-CZ3 4.35Å; I194-W196 PolarHBondContact O-N 3.36Å; I194-A197 HydrophobicContact CB-CB 3.9Å; I194-A197 HydrophobicContact CG2-CB 3.84Å; I194-A197 VanDerWaalsContact O-CB 3.32Å; I194-A197 WeakPolarHBondContact O-CB 3.29Å; I194-A197 PolarHBondContact O-N 2.92Å; I194-A337 HydrophobicContact CD1-CB 4.26Å; I194-A337 PolarHBondContact N-O 2.97Å
195	P	88.3	Confident	91.9	Very high	95 Å²	95	56 Å²	56	62%	0.617	31%	0.305	S	S	*	.	T	Hydrogen-bonded Turn	trans	-70	-26	-170.5	26.8	-34.9	0	0	0	114.2
196	W	90.7	Very high	92.1	Very high	149 Å²	149	58 Å²	58	56%	0.564	32%	0.318	S	S	*	.	T	Hydrogen-bonded Turn	trans	-87.4	-7.9	177.5	55.1	-102	0	0	0	113.3	I194 F198 A199 M200 F334	I194-W196 VanDerWaalsContact C-N 3.34Å; I194-W196 HydrophobicContact CG2-CD2 3.52Å; I194-W196 HydrophobicContact CG2-CE3 4.09Å; I194-W196 HydrophobicContact CG2-CG 3.91Å; I194-W196 HydrophobicContact CG2-CH2 4.11Å; I194-W196 HydrophobicContact CG2-CZ2 3.54Å; I194-W196 HydrophobicContact CG2-CZ3 4.35Å; I194-W196 PolarHBondContact O-N 3.36Å; W196-F198 VanDerWaalsContact C-N 3.34Å; W196-F198 PolarHBondContact O-N 3.11Å; W196-A199 PolarHBondContact O-N 3.07Å; W196-M200 HydrophobicContact CE3-CB 4.38Å; W196-M200 HydrophobicContact CE3-CG 3.53Å; W196-M200 HydrophobicContact CZ3-CB 4.45Å; W196-M200 HydrophobicContact CZ3-CG 3.8Å; W196-M200 PolarHBondContact O-N 2.91Å; W196-F334 HydrophobicContact CH2-CE1 4.26Å; W196-F334 HydrophobicContact CZ3-CD1 4.37Å; W196-F334 AromaticContact CZ3-CE1 3.88Å; W196-F334 HydrophobicContact CZ3-CE1 3.88Å; W196-F334 HydrophobicContact CZ3-CZ 4.42Å
197	A	93.7	Very high	92.3	Very high	0 Å²	0	55 Å²	55	0%	0	30%	0.303	C	S	.	.	H	α-helix	trans	-63.2	-41.2	-173.2	0	0	0	0	0	111.4	I194 A199 M200 A201 F334 A337 A338	I194-A197 HydrophobicContact CB-CB 3.9Å; I194-A197 HydrophobicContact CG2-CB 3.84Å; I194-A197 VanDerWaalsContact O-CB 3.32Å; I194-A197 WeakPolarHBondContact O-CB 3.29Å; I194-A197 PolarHBondContact O-N 2.92Å; A197-A199 VanDerWaalsContact C-N 3.35Å; A197-A199 PolarHBondContact O-N 2.93Å; A197-M200 CarbonylContact O-C 3.58Å; A197-M200 WeakPolarHBondContact O-CA 3.43Å; A197-M200 WeakPolarHBondContact O-CB 3.48Å; A197-M200 PolarHBondContact O-N 2.91Å; A197-A201 PolarHBondContact O-N 3.14Å; A197-F334 HydrophobicContact CB-CB 4.27Å; A197-F334 HydrophobicContact CB-CD1 4.17Å; A197-F334 WeakPolarHBondContact CB-O 3.31Å; A197-F334 WeakPolarHBondContact O-CB 3.46Å; A197-A337 HydrophobicContact CB-CB 4.03Å; A197-A338 HydrophobicContact CB-CB 4.32Å
198	F	91.4	Very high	92.6	Very high	13 Å²	13	52.3 Å²	52.3	6%	0.057	29%	0.291	C	S	.	.	H	α-helix	trans	-60.8	-43.2	-178.8	-159.7	-109	0	0	0	112.8	W196 M200 A201 E202 S283 H298 A338 E340	W196-F198 VanDerWaalsContact C-N 3.34Å; W196-F198 PolarHBondContact O-N 3.11Å; F198-M200 VanDerWaalsContact C-N 3.26Å; F198-M200 PolarHBondContact O-N 2.93Å; F198-A201 WeakPolarHBondContact O-CB 3.44Å; F198-A201 PolarHBondContact O-N 2.89Å; F198-A201 VanDerWaalsContact O-N 3.1Å; F198-E202 HydrophobicContact CE1-CG 4.31Å; F198-E202 WeakPolarHBondContact CE1-OE1 3.47Å; F198-E202 PolarHBondContact O-N 3.35Å; F198-S283 WeakPolarHBondContact CD1-OG 3.2Å; F198-S283 VanDerWaalsContact CE1-OG 3.24Å; F198-S283 WeakPolarHBondContact CE1-OG 3.28Å; F198-H298 AromaticContact CZ-CE1 3.58Å; F198-H298 AromaticContact CZ-ND1 3.69Å; F198-A338 HydrophobicContact CB-CB 3.65Å; F198-A338 HydrophobicContact CD2-CB 3.95Å; F198-A338 HydrophobicContact CG-CB 4.24Å; F198-E340 VanDerWaalsContact CD1-OE2 3.27Å; F198-E340 WeakPolarHBondContact CD1-OE2 3.38Å; F198-E340 HydrophobicContact CD2-CB 4.25Å; F198-E340 HydrophobicContact CD2-CG 4.3Å; F198-E340 WeakPolarHBondContact CD2-OE2 3.26Å; F198-E340 VanDerWaalsContact CE1-OE2 3.27Å; F198-E340 WeakPolarHBondContact CE1-OE2 3.48Å; F198-E340 HydrophobicContact CE2-CB 4.25Å; F198-E340 WeakPolarHBondContact CE2-OE2 3.34Å; F198-E340 VanDerWaalsContact CG-OE2 3.3Å; F198-E340 WeakPolarHBondContact CG-OE2 3.39Å; F198-E340 VanDerWaalsContact CZ-OE2 3.29Å; F198-E340 WeakPolarHBondContact CZ-OE2 3.36Å
199	A	92	Very high	93	Very high	35 Å²	35	53.7 Å²	53.7	29%	0.289	30%	0.302	S	S	.	.	H	α-helix	trans	-61.3	-34.9	174.5	0	0	0	0	0	112.3	W196 A197 A203	W196-A199 PolarHBondContact O-N 3.07Å; A197-A199 VanDerWaalsContact C-N 3.35Å; A197-A199 PolarHBondContact O-N 2.93Å; A199-A203 WeakPolarHBondContact O-CB 3.29Å; A199-A203 PolarHBondContact O-N 3.2Å
200	M	94.4	Very high	93.4	Very high	84 Å²	84	52.4 Å²	52.4	41%	0.414	30%	0.295	S	S	.	.	H	α-helix	trans	-72.2	-34	174.5	-66.3	-60.7	98.3	0	0	112.7	W196 A197 F198 A203 C204 F334	W196-M200 HydrophobicContact CE3-CB 4.38Å; W196-M200 HydrophobicContact CE3-CG 3.53Å; W196-M200 HydrophobicContact CZ3-CB 4.45Å; W196-M200 HydrophobicContact CZ3-CG 3.8Å; W196-M200 PolarHBondContact O-N 2.91Å; A197-M200 CarbonylContact O-C 3.58Å; A197-M200 WeakPolarHBondContact O-CA 3.43Å; A197-M200 WeakPolarHBondContact O-CB 3.48Å; A197-M200 PolarHBondContact O-N 2.91Å; F198-M200 VanDerWaalsContact C-N 3.26Å; F198-M200 PolarHBondContact O-N 2.93Å; M200-A203 PolarHBondContact O-N 3.04Å; M200-C204 PolarHBondContact O-N 3.12Å; M200-C204 PolarHBondContact O-SG 3.23Å; M200-F334 HydrophobicContact CB-CD2 3.78Å; M200-F334 HydrophobicContact CB-CE2 3.9Å; M200-F334 HydrophobicContact CB-CG 4.16Å; M200-F334 HydrophobicContact CB-CZ 4.38Å
201	A	94.4	Very high	93.6	Very high	0 Å²	0	49.5 Å²	49.5	0%	0	27%	0.272	C	S	.	.	H	α-helix	trans	-62	-45.8	171.9	0	0	0	0	0	111.3	A197 F198 A203 C204 G205 F334 I335	A197-A201 PolarHBondContact O-N 3.14Å; F198-A201 WeakPolarHBondContact O-CB 3.44Å; F198-A201 PolarHBondContact O-N 2.89Å; F198-A201 VanDerWaalsContact O-N 3.1Å; A201-A203 VanDerWaalsContact C-N 3.35Å; A201-A203 PolarHBondContact O-N 3.05Å; A201-C204 WeakPolarHBondContact O-CB 3.43Å; A201-C204 PolarHBondContact O-N 2.99Å; A201-G205 PolarHBondContact O-N 3.47Å; A201-F334 HydrophobicContact CB-CB 3.77Å; A201-I335 HydrophobicContact CB-CG1 3.71Å
202	E	93.8	Very high	93.9	Very high	5 Å²	5	47.9 Å²	47.9	2%	0.023	26%	0.262	C	S	.	.	H	α-helix	trans	-63.2	-41.2	175.6	-67.5	-175.1	169.3	0	0	111.6	F198 C204 G205 V206 S283 L284 H298	F198-E202 HydrophobicContact CE1-CG 4.31Å; F198-E202 WeakPolarHBondContact CE1-OE1 3.47Å; F198-E202 PolarHBondContact O-N 3.35Å; E202-C204 VanDerWaalsContact C-N 3.32Å; E202-C204 PolarHBondContact O-N 3.43Å; E202-G205 PolarHBondContact O-N 2.83Å; E202-G205 VanDerWaalsContact O-N 3.13Å; E202-V206 WeakPolarHBondContact O-CG2 3.4Å; E202-V206 PolarHBondContact O-N 3.48Å; E202-S283 WeakPolarHBondContact OE1-CA 3.47Å; E202-S283 VanDerWaalsContact OE1-CB 3.32Å; E202-S283 WeakPolarHBondContact OE1-CB 3.17Å; E202-S283 PolarHBondContact OE1-N 3.1Å; E202-S283 PolarHBondContact OE1-OG 3.07Å; E202-S283 PolarHBondContact OE2-OG 3.4Å; E202-S283 VanDerWaalsContact OE2-OG 3.04Å; E202-L284 HydrophobicContact CB-CD1 3.5Å; E202-L284 HydrophobicContact CB-CG 4.44Å; E202-L284 HydrophobicContact CG-CD1 4.42Å; E202-L284 VanDerWaalsContact OE2-CB 3.27Å; E202-L284 WeakPolarHBondContact OE2-CB 3.44Å; E202-L284 WeakPolarHBondContact OE2-CD1 3.48Å; E202-L284 WeakPolarHBondContact OE2-CG 3.29Å; E202-L284 PolarHBondContact OE2-N 3.14Å; E202-H298 IonicContact OE1-NE2 3.91Å
203	A	94.8	Very high	94.1	Very high	32 Å²	32	46.8 Å²	46.8	26%	0.264	25%	0.25	S	C	.	.	H	α-helix	trans	-58.5	-42.7	173.3	0	0	0	0	0	112	A199 M200 A201 G205 V206 I207	A199-A203 WeakPolarHBondContact O-CB 3.29Å; A199-A203 PolarHBondContact O-N 3.2Å; M200-A203 PolarHBondContact O-N 3.04Å; A201-A203 VanDerWaalsContact C-N 3.35Å; A201-A203 PolarHBondContact O-N 3.05Å; A203-G205 VanDerWaalsContact C-N 3.34Å; A203-G205 PolarHBondContact O-N 2.83Å; A203-V206 PolarHBondContact O-N 3Å; A203-I207 WeakPolarHBondContact O-CD1 3.26Å; A203-I207 VanDerWaalsContact O-CG1 3.23Å; A203-I207 WeakPolarHBondContact O-CG1 3.21Å; A203-I207 PolarHBondContact O-N 3.3Å
204	C	96.4	Very high	94.2	Very high	12 Å²	12	46.7 Å²	46.7	8%	0.081	26%	0.257	C	S	.	.	H	α-helix	trans	-59.9	-43.7	174.4	-66.7	0	0	0	0	111.7	M200 A201 E202 I207 L208 L327	M200-C204 PolarHBondContact O-N 3.12Å; M200-C204 PolarHBondContact O-SG 3.23Å; A201-C204 WeakPolarHBondContact O-CB 3.43Å; A201-C204 PolarHBondContact O-N 2.99Å; E202-C204 VanDerWaalsContact C-N 3.32Å; E202-C204 PolarHBondContact O-N 3.43Å; C204-I207 PolarHBondContact O-N 2.94Å; C204-L208 PolarHBondContact O-N 3.29Å; C204-L327 HydrophobicContact CB-CD2 4.21Å
205	G	95.5	Very high	94.2	Very high	11 Å²	11	45 Å²	45	11%	0.113	25%	0.248	C	C	.	.	H	α-helix	trans	-62.6	-43.2	175.8	0	0	0	0	0	113.1	A201 E202 A203 L208 C209	A201-G205 PolarHBondContact O-N 3.47Å; E202-G205 PolarHBondContact O-N 2.83Å; E202-G205 VanDerWaalsContact O-N 3.13Å; A203-G205 VanDerWaalsContact C-N 3.34Å; A203-G205 PolarHBondContact O-N 2.83Å; G205-L208 PolarHBondContact O-N 3.41Å; G205-C209 VanDerWaalsContact O-CB 3.31Å; G205-C209 WeakPolarHBondContact O-CB 3.49Å; G205-C209 PolarHBondContact O-N 2.84Å
206	V	95.6	Very high	94.3	Very high	61 Å²	61	41.5 Å²	41.5	37%	0.37	22%	0.224	S	C	.	.	H	α-helix	trans	-63.8	-42.5	175.9	171.4	0	0	0	0	111.1	E202 A203 C209 N210 M282	E202-V206 WeakPolarHBondContact O-CG2 3.4Å; E202-V206 PolarHBondContact O-N 3.48Å; A203-V206 PolarHBondContact O-N 3Å; V206-C209 WeakPolarHBondContact O-CB 3.08Å; V206-C209 PolarHBondContact O-N 3.45Å; V206-N210 PolarHBondContact O-N 2.62Å; V206-N210 PolarHBondContact O-ND2 3Å; V206-M282 HydrophobicContact CG2-SD 4.21Å
207	I	96.3	Very high	94.3	Very high	80 Å²	80	38.9 Å²	38.9	41%	0.41	22%	0.221	S	C	.	.	H	α-helix	trans	-61.9	-48	176.6	-67	163.1	0	0	0	110.4	A203 C204 C209 N210 I211 L327	A203-I207 WeakPolarHBondContact O-CD1 3.26Å; A203-I207 VanDerWaalsContact O-CG1 3.23Å; A203-I207 WeakPolarHBondContact O-CG1 3.21Å; A203-I207 PolarHBondContact O-N 3.3Å; C204-I207 PolarHBondContact O-N 2.94Å; I207-C209 VanDerWaalsContact C-N 3.3Å; I207-C209 PolarHBondContact O-N 2.8Å; I207-N210 PolarHBondContact O-N 3.38Å; I207-I211 HydrophobicContact CG2-CD1 3.99Å; I207-I211 WeakPolarHBondContact O-CG1 3.29Å; I207-I211 PolarHBondContact O-N 2.89Å; I207-L327 HydrophobicContact CB-CD1 4.24Å; I207-L327 HydrophobicContact CG2-CD1 3.57Å
208	L	97	Very high	94	Very high	0 Å²	0	40.7 Å²	40.7	0%	0	23%	0.23	C	C	.	.	H	α-helix	trans	-59.7	-40.5	175.6	-80	169.5	0	0	0	112.3	C204 G205 I211 W212 I302 L305 L327	C204-L208 PolarHBondContact O-N 3.29Å; G205-L208 PolarHBondContact O-N 3.41Å; L208-I211 PolarHBondContact O-N 3.37Å; L208-W212 WeakPolarHBondContact O-CB 3.46Å; L208-W212 PolarHBondContact O-N 3.31Å; L208-I302 HydrophobicContact CD1-CB 4.42Å; L208-I302 HydrophobicContact CD1-CG2 3.66Å; L208-L305 HydrophobicContact CB-CB 4.11Å; L208-L305 HydrophobicContact CB-CD1 4.21Å; L208-L327 HydrophobicContact CD1-CB 4Å; L208-L327 HydrophobicContact CD2-CB 4.19Å; L208-L327 HydrophobicContact CD2-CD1 4.08Å; L208-L327 HydrophobicContact CG-CB 3.93Å; L208-L327 HydrophobicContact CG-CD1 3.98Å
209	C	96.1	Very high	93.9	Very high	48 Å²	48	40.2 Å²	40.2	32%	0.324	23%	0.228	S	C	.	.	H	α-helix	trans	-62.1	-44.4	176.8	-172.8	0	0	0	0	111	G205 V206 I207 W212 L213 L305	G205-C209 VanDerWaalsContact O-CB 3.31Å; G205-C209 WeakPolarHBondContact O-CB 3.49Å; G205-C209 PolarHBondContact O-N 2.84Å; V206-C209 WeakPolarHBondContact O-CB 3.08Å; V206-C209 PolarHBondContact O-N 3.45Å; I207-C209 VanDerWaalsContact C-N 3.3Å; I207-C209 PolarHBondContact O-N 2.8Å; C209-W212 PolarHBondContact O-N 3Å; C209-L213 WeakPolarHBondContact O-CB 3.22Å; C209-L213 VanDerWaalsContact O-CG 3.27Å; C209-L213 WeakPolarHBondContact O-CG 3.4Å; C209-L213 PolarHBondContact O-N 3.11Å; C209-L305 HydrophobicContact CB-CD1 3.92Å
210	N	96	Very high	93.4	Very high	96 Å²	96	44.4 Å²	44.4	51%	0.513	24%	0.24	S	C	.	.	H	α-helix	trans	-63.3	-43.1	176	-80.6	-77.7	0	0	0	112.5	V206 I207 W212 L213 L214	V206-N210 PolarHBondContact O-N 2.62Å; V206-N210 PolarHBondContact O-ND2 3Å; I207-N210 PolarHBondContact O-N 3.38Å; N210-W212 VanDerWaalsContact C-N 3.32Å; N210-W212 PolarHBondContact O-N 3.4Å; N210-L213 PolarHBondContact O-N 3.28Å; N210-L214 PolarHBondContact O-N 3.1Å
211	I	95.4	Very high	93	Very high	31 Å²	31	41.6 Å²	41.6	16%	0.159	23%	0.225	C	C	.	.	H	α-helix	trans	-59.3	-47	174.7	-66.4	166.8	0	0	0	109.9	I207 L208 L214 V215 V309 I320 L323 L327	I207-I211 HydrophobicContact CG2-CD1 3.99Å; I207-I211 WeakPolarHBondContact O-CG1 3.29Å; I207-I211 PolarHBondContact O-N 2.89Å; L208-I211 PolarHBondContact O-N 3.37Å; I211-L214 WeakPolarHBondContact O-CB 3.36Å; I211-L214 PolarHBondContact O-N 2.93Å; I211-V215 WeakPolarHBondContact O-CG2 3.44Å; I211-V215 PolarHBondContact O-N 3Å; I211-V309 HydrophobicContact CG2-CG1 4.02Å; I211-V309 HydrophobicContact CG2-CG2 3.99Å; I211-I320 HydrophobicContact CG2-CG2 4.14Å; I211-L323 HydrophobicContact CD1-CD2 4Å; I211-L327 HydrophobicContact CD1-CD1 4.21Å
212	W	95.9	Very high	92.7	Very high	4 Å²	4	46.8 Å²	46.8	2%	0.015	25%	0.245	C	C	.	.	H	α-helix	trans	-63.3	-43.9	178.5	171.8	-112.3	0	0	0	112.8	L208 C209 N210 L214 V215 L216 L225 L229 L305 F308 V309 Y312	L208-W212 WeakPolarHBondContact O-CB 3.46Å; L208-W212 PolarHBondContact O-N 3.31Å; C209-W212 PolarHBondContact O-N 3Å; N210-W212 VanDerWaalsContact C-N 3.32Å; N210-W212 PolarHBondContact O-N 3.4Å; W212-L214 VanDerWaalsContact C-N 3.29Å; W212-L214 PolarHBondContact O-N 2.96Å; W212-V215 HydrophobicContact CE3-CB 4.3Å; W212-V215 HydrophobicContact CE3-CG1 4.22Å; W212-V215 HydrophobicContact CZ3-CG1 4.02Å; W212-V215 WeakPolarHBondContact O-CB 3.37Å; W212-V215 PolarHBondContact O-N 3.5Å; W212-L216 HydrophobicContact CZ2-CD1 4.12Å; W212-L216 WeakPolarHBondContact O-CB 3.23Å; W212-L216 PolarHBondContact O-N 3.02Å; W212-L225 HydrophobicContact CH2-CB 4.08Å; W212-L225 HydrophobicContact CH2-CD2 3.93Å; W212-L225 HydrophobicContact CH2-CG 4.17Å; W212-L225 HydrophobicContact CZ2-CB 4.34Å; W212-L229 HydrophobicContact CZ2-CD2 4.35Å; W212-L305 HydrophobicContact CB-CD2 3.85Å; W212-L305 HydrophobicContact CG-CD2 3.84Å; W212-F308 HydrophobicContact CD2-CB 4.19Å; W212-F308 HydrophobicContact CE3-CB 3.81Å; W212-F308 HydrophobicContact CH2-CB 3.95Å; W212-F308 AromaticContact CH2-CD1 3.44Å; W212-F308 HydrophobicContact CH2-CD1 3.44Å; W212-F308 VanDerWaalsContact CH2-CD1 3.44Å; W212-F308 HydrophobicContact CH2-CE1 4.37Å; W212-F308 HydrophobicContact CH2-CG 4.13Å; W212-F308 HydrophobicContact CZ2-CB 4.3Å; W212-F308 AromaticContact CZ2-CD1 3.7Å; W212-F308 HydrophobicContact CZ2-CD1 3.7Å; W212-F308 HydrophobicContact CZ2-CE1 4.43Å; W212-F308 HydrophobicContact CZ2-CG 4.3Å; W212-F308 HydrophobicContact CZ3-CB 3.7Å; W212-F308 HydrophobicContact CZ3-CD1 4.05Å; W212-F308 HydrophobicContact CZ3-CG 4.37Å; W212-F308 WeakPolarHBondContact CZ3-O 3.27Å; W212-V309 HydrophobicContact CB-CG2 3.95Å; W212-V309 HydrophobicContact CE3-CG2 4.21Å; W212-Y312 AromaticContact CH2-CD2 3.91Å; W212-Y312 HydrophobicContact CH2-CD2 3.91Å; W212-Y312 HydrophobicContact CH2-CG 4.41Å; W212-Y312 HydrophobicContact CZ3-CD2 4.04Å; W212-Y312 HydrophobicContact CZ3-CG 4.45Å
213	L	94.7	Very high	92.5	Very high	81 Å²	81	47 Å²	47	42%	0.424	25%	0.247	S	C	.	.	H	α-helix	trans	-59.5	-41.4	175.7	-72.9	172.7	0	0	0	111.2	C209 N210 L216 L217	C209-L213 WeakPolarHBondContact O-CB 3.22Å; C209-L213 VanDerWaalsContact O-CG 3.27Å; C209-L213 WeakPolarHBondContact O-CG 3.4Å; C209-L213 PolarHBondContact O-N 3.11Å; N210-L213 PolarHBondContact O-N 3.28Å; L213-L216 PolarHBondContact O-N 3.13Å; L213-L217 WeakPolarHBondContact O-CB 3.44Å; L213-L217 VanDerWaalsContact O-CG 3.22Å; L213-L217 WeakPolarHBondContact O-CG 3.43Å; L213-L217 PolarHBondContact O-N 3.45Å
214	L	92.9	Very high	92.2	Very high	102 Å²	102	45.7 Å²	45.7	53%	0.534	24%	0.236	S	C	.	.	H	α-helix	trans	-62.4	-45.3	174.8	-177.2	65.4	0	0	0	111.7	N210 I211 W212 L216 L217 L218	N210-L214 PolarHBondContact O-N 3.1Å; I211-L214 WeakPolarHBondContact O-CB 3.36Å; I211-L214 PolarHBondContact O-N 2.93Å; W212-L214 VanDerWaalsContact C-N 3.29Å; W212-L214 PolarHBondContact O-N 2.96Å; L214-L216 VanDerWaalsContact C-N 3.34Å; L214-L216 PolarHBondContact O-N 3.21Å; L214-L217 PolarHBondContact O-N 3.4Å; L214-L218 HydrophobicContact CD1-CD1 3.94Å; L214-L218 HydrophobicContact CD1-CG 4.28Å; L214-L218 HydrophobicContact CG-CD1 3.99Å; L214-L218 VanDerWaalsContact O-CG 3.29Å; L214-L218 WeakPolarHBondContact O-CG 3.46Å; L214-L218 PolarHBondContact O-N 2.98Å; L214-L218 VanDerWaalsContact O-N 3.07Å
215	V	92.1	Very high	92	Very high	6 Å²	6	45.1 Å²	45.1	4%	0.036	23%	0.232	C	C	.	.	H	α-helix	trans	-57.9	-48.3	174.4	169.4	0	0	0	0	110.4	I211 W212 L217 L218 H219 T313 Y397	I211-V215 WeakPolarHBondContact O-CG2 3.44Å; I211-V215 PolarHBondContact O-N 3Å; W212-V215 HydrophobicContact CE3-CB 4.3Å; W212-V215 HydrophobicContact CE3-CG1 4.22Å; W212-V215 HydrophobicContact CZ3-CG1 4.02Å; W212-V215 WeakPolarHBondContact O-CB 3.37Å; W212-V215 PolarHBondContact O-N 3.5Å; V215-L217 VanDerWaalsContact C-N 3.34Å; V215-L217 PolarHBondContact O-N 3.38Å; V215-L218 PolarHBondContact O-N 3.46Å; V215-H219 VanDerWaalsContact O-CB 3.27Å; V215-H219 WeakPolarHBondContact O-CB 3.39Å; V215-H219 PolarHBondContact O-N 3.48Å; V215-T313 HydrophobicContact CB-CG2 4.47Å; V215-T313 HydrophobicContact CG1-CG2 4.03Å; V215-T313 HydrophobicContact CG2-CG2 3.53Å; V215-Y397 HydrophobicContact CG1-CE1 4.38Å
216	L	91.9	Very high	91.8	Very high	21 Å²	21	47.5 Å²	47.5	11%	0.11	24%	0.242	C	C	.	.	H	α-helix	trans	-61.2	-40.8	-179.9	-172.4	70.7	0	0	0	112.3	W212 L213 L214 R222 L225 L226	W212-L216 HydrophobicContact CZ2-CD1 4.12Å; W212-L216 WeakPolarHBondContact O-CB 3.23Å; W212-L216 PolarHBondContact O-N 3.02Å; L213-L216 PolarHBondContact O-N 3.13Å; L214-L216 VanDerWaalsContact C-N 3.34Å; L214-L216 PolarHBondContact O-N 3.21Å; L216-R222 HydrophobicContact CD1-CB 4.21Å; L216-R222 WeakPolarHBondContact CD1-O 3.24Å; L216-R222 HydrophobicContact CG-CB 4.42Å; L216-R222 VanDerWaalsContact O-CB 3.24Å; L216-R222 WeakPolarHBondContact O-CB 3.42Å; L216-L225 HydrophobicContact CD1-CB 3.66Å; L216-L225 HydrophobicContact CD1-CD2 4.46Å; L216-L226 HydrophobicContact CD1-CB 4.22Å; L216-L226 HydrophobicContact CD2-CB 4.38Å; L216-L226 HydrophobicContact CD2-CD1 4.09Å
217	L	89.8	Confident	91.6	Very high	95 Å²	95	44.8 Å²	44.8	50%	0.497	23%	0.225	S	C	.	.	H	α-helix	trans	-65.9	-39.1	178.3	-74.5	173.1	0	0	0	112.3	L213 L214 V215 P400	L213-L217 WeakPolarHBondContact O-CB 3.44Å; L213-L217 VanDerWaalsContact O-CG 3.22Å; L213-L217 WeakPolarHBondContact O-CG 3.43Å; L213-L217 PolarHBondContact O-N 3.45Å; L214-L217 PolarHBondContact O-N 3.4Å; V215-L217 VanDerWaalsContact C-N 3.34Å; V215-L217 PolarHBondContact O-N 3.38Å; L217-P400 WeakPolarHBondContact O-CG 3.44Å
218	L	88.4	Confident	91.4	Very high	37 Å²	37	41 Å²	41	19%	0.194	21%	0.206	C	C	.	.	H	α-helix	trans	-85.9	-14.1	-178.2	-61.1	175	0	0	0	113.2	L214 V215 Y397 G398 W399	L214-L218 HydrophobicContact CD1-CD1 3.94Å; L214-L218 HydrophobicContact CD1-CG 4.28Å; L214-L218 HydrophobicContact CG-CD1 3.99Å; L214-L218 VanDerWaalsContact O-CG 3.29Å; L214-L218 WeakPolarHBondContact O-CG 3.46Å; L214-L218 PolarHBondContact O-N 2.98Å; L214-L218 VanDerWaalsContact O-N 3.07Å; V215-L218 PolarHBondContact O-N 3.46Å; L218-Y397 HydrophobicContact CB-CD1 3.73Å; L218-Y397 HydrophobicContact CB-CE1 4.27Å; L218-Y397 CarbonylContact O-C 3.51Å; L218-Y397 VanDerWaalsContact O-CA 3.28Å; L218-Y397 WeakPolarHBondContact O-CA 3.05Å; L218-Y397 WeakPolarHBondContact O-CD1 3.46Å; L218-G398 CarbonylContact C-O 3.52Å; L218-G398 PolarHBondContact O-N 3.01Å; L218-W399 HydrophobicContact CD2-CE3 3.68Å; L218-W399 HydrophobicContact CD2-CZ3 3.68Å
219	H	87.7	Confident	91.3	Very high	3 Å²	3	42.1 Å²	42.1	1%	0.014	21%	0.211	C	C	.	.	B	Isolated β-bridge	trans	-80.4	132.7	-177.7	-159.4	-87.6	0	0	0	111.7	V215 H221 R222 L225 P394	V215-H219 VanDerWaalsContact O-CB 3.27Å; V215-H219 WeakPolarHBondContact O-CB 3.39Å; V215-H219 PolarHBondContact O-N 3.48Å; H219-H221 VanDerWaalsContact C-N 3.3Å; H219-H221 PolarHBondContact ND1-N 3.41Å; H219-H221 VanDerWaalsContact ND1-N 3.19Å; H219-H221 PolarHBondContact O-N 2.91Å; H219-R222 PolarHBondContact O-N 2.94Å; H219-L225 HydrophobicContact CB-CD2 3.92Å; H219-P394 PolarHBondContact CE1-O 2.83Å; H219-P394 PolarHBondContact NE2-O 3.02Å
220	K	82.9	Confident	91.2	Very high	123 Å²	123	40.4 Å²	40.4	54%	0.535	20%	0.199	S	C	.	.	T	Hydrogen-bonded Turn	trans	-62.6	-36.3	-178.7	-175.1	178.3	174.1	-175.4	0	112.8	R222 E396	K220-R222 PolarHBondContact O-N 2.96Å; K220-E396 HydrophobicContact CB-CB 4.21Å; K220-E396 VanDerWaalsContact CB-O 3.31Å; K220-E396 WeakPolarHBondContact CB-O 3.49Å; K220-E396 HydrophobicContact CD-CB 4.11Å; K220-E396 VanDerWaalsContact CD-OE2 3.26Å; K220-E396 WeakPolarHBondContact CD-OE2 3.05Å; K220-E396 PolarHBondContact N-O 3.36Å; K220-E396 IonicContact NZ-OE2 3.36Å; K220-E396 PolarHBondContact NZ-OE2 3.17Å
221	H	85.8	Confident	91.1	Very high	25 Å²	25	36 Å²	36	12%	0.116	18%	0.176	C	C	.	.	T	Hydrogen-bonded Turn	trans	-96.7	36	-179.2	-59.5	-69.3	0	0	0	114	H219 S223 V224 L225 V393	H219-H221 VanDerWaalsContact C-N 3.3Å; H219-H221 PolarHBondContact ND1-N 3.41Å; H219-H221 VanDerWaalsContact ND1-N 3.19Å; H219-H221 PolarHBondContact O-N 2.91Å; H221-S223 VanDerWaalsContact C-N 3.26Å; H221-S223 PolarHBondContact O-N 3.47Å; H221-S223 VanDerWaalsContact O-N 3.11Å; H221-V224 PolarHBondContact O-N 3.5Å; H221-L225 HydrophobicContact CB-CD1 4.4Å; H221-L225 WeakPolarHBondContact O-CD1 3.35Å; H221-L225 PolarHBondContact O-N 2.86Å; H221-V393 HydrophobicContact CB-CG1 3.9Å
222	R	88.6	Confident	91	Very high	110 Å²	110	34.9 Å²	34.9	42%	0.415	17%	0.171	S	C	.	.	H	α-helix	trans	-50.3	-36.2	-174.4	63.9	-171.4	178.9	-168.9	0.1	115.7	L216 H219 K220 L225 L226	L216-R222 HydrophobicContact CD1-CB 4.21Å; L216-R222 WeakPolarHBondContact CD1-O 3.24Å; L216-R222 HydrophobicContact CG-CB 4.42Å; L216-R222 VanDerWaalsContact O-CB 3.24Å; L216-R222 WeakPolarHBondContact O-CB 3.42Å; H219-R222 PolarHBondContact O-N 2.94Å; K220-R222 PolarHBondContact O-N 2.96Å; R222-L225 PolarHBondContact O-N 2.86Å; R222-L226 WeakPolarHBondContact O-CB 3.22Å; R222-L226 PolarHBondContact O-N 3.37Å
223	S	87.6	Confident	91	Very high	10 Å²	10	35.5 Å²	35.5	7%	0.07	17%	0.174	C	C	.	.	H	α-helix	trans	-64.5	-41.3	179.4	52.7	0	0	0	0	112.4	P144 T149 H221 R227	P144-S223 WeakPolarHBondContact CB-OG 3.4Å; T149-S223 WeakPolarHBondContact CG2-O 3.41Å; T149-S223 PolarHBondContact OG1-O 3.26Å; H221-S223 VanDerWaalsContact C-N 3.26Å; H221-S223 PolarHBondContact O-N 3.47Å; H221-S223 VanDerWaalsContact O-N 3.11Å; S223-R227 VanDerWaalsContact O-CB 3.29Å; S223-R227 WeakPolarHBondContact O-CB 3.23Å; S223-R227 PolarHBondContact O-N 2.88Å
224	V	89.1	Confident	90.9	Very high	3 Å²	3	31.7 Å²	31.7	2%	0.018	15%	0.154	C	C	.	.	H	α-helix	trans	-66.9	-45.9	177.9	-179.9	0	0	0	0	110.3	H221 L226 R227 R228 V389 V393	H221-V224 PolarHBondContact O-N 3.5Å; V224-L226 PolarHBondContact O-N 3.3Å; V224-R227 PolarHBondContact O-N 3.2Å; V224-R228 HydrophobicContact CG1-CG 4.49Å; V224-R228 VanDerWaalsContact O-CG 3.27Å; V224-R228 WeakPolarHBondContact O-CG 3.3Å; V224-R228 PolarHBondContact O-N 3.31Å; V224-V389 HydrophobicContact CG1-CG2 4.24Å; V224-V389 HydrophobicContact CG2-CG2 4.38Å; V224-V393 HydrophobicContact CG1-CG2 3.99Å
225	L	91.8	Very high	91	Very high	0 Å²	0	29.5 Å²	29.5	0%	0	15%	0.145	C	C	.	.	H	α-helix	trans	-60.3	-47.3	177.9	-86.5	60.9	0	0	0	111.5	W212 L216 H219 H221 R222 R227 R228 L229 Y312 V393	W212-L225 HydrophobicContact CH2-CB 4.08Å; W212-L225 HydrophobicContact CH2-CD2 3.93Å; W212-L225 HydrophobicContact CH2-CG 4.17Å; W212-L225 HydrophobicContact CZ2-CB 4.34Å; L216-L225 HydrophobicContact CD1-CB 3.66Å; L216-L225 HydrophobicContact CD1-CD2 4.46Å; H219-L225 HydrophobicContact CB-CD2 3.92Å; H221-L225 HydrophobicContact CB-CD1 4.4Å; H221-L225 WeakPolarHBondContact O-CD1 3.35Å; H221-L225 PolarHBondContact O-N 2.86Å; R222-L225 PolarHBondContact O-N 2.86Å; L225-R227 PolarHBondContact O-N 3.43Å; L225-R228 PolarHBondContact O-N 3.28Å; L225-L229 PolarHBondContact O-N 3.29Å; L225-Y312 HydrophobicContact CD1-CD1 3.64Å; L225-Y312 HydrophobicContact CD1-CE1 3.7Å; L225-Y312 HydrophobicContact CD1-CG 4.37Å; L225-Y312 HydrophobicContact CD2-CD1 3.83Å; L225-Y312 HydrophobicContact CD2-CD2 4.44Å; L225-Y312 HydrophobicContact CD2-CG 3.76Å; L225-Y312 HydrophobicContact CG-CD1 3.56Å; L225-Y312 HydrophobicContact CG-CD2 4.21Å; L225-Y312 HydrophobicContact CG-CE1 3.79Å; L225-Y312 HydrophobicContact CG-CE2 4.46Å; L225-Y312 HydrophobicContact CG-CG 3.78Å; L225-V393 HydrophobicContact CD1-CG1 4.04Å
226	L	91.6	Very high	91.1	Very high	62 Å²	62	29.2 Å²	29.2	33%	0.325	14%	0.143	S	C	.	.	H	α-helix	trans	-61.3	-45.7	178	-177.5	61	0	0	0	111.3	T149 L216 R222 V224 R228 L229 C230	T149-L226 HydrophobicContact CG2-CB 4.25Å; T149-L226 HydrophobicContact CG2-CD2 4.03Å; T149-L226 HydrophobicContact CG2-CG 4.24Å; L216-L226 HydrophobicContact CD1-CB 4.22Å; L216-L226 HydrophobicContact CD2-CB 4.38Å; L216-L226 HydrophobicContact CD2-CD1 4.09Å; R222-L226 WeakPolarHBondContact O-CB 3.22Å; R222-L226 PolarHBondContact O-N 3.37Å; V224-L226 PolarHBondContact O-N 3.3Å; L226-R228 VanDerWaalsContact C-N 3.33Å; L226-R228 PolarHBondContact O-N 2.86Å; L226-L229 PolarHBondContact O-N 2.96Å; L226-C230 WeakPolarHBondContact O-CB 3.35Å; L226-C230 PolarHBondContact O-N 2.87Å; L226-C230 PolarHBondContact O-SG 2.89Å
227	R	91.8	Very high	91.2	Very high	3 Å²	3	28.9 Å²	28.9	1%	0.011	14%	0.141	C	C	.	.	H	α-helix	trans	-58.5	-43.8	176.5	-175.9	-178.4	69.8	-172.7	5.5	112.1	E145 T149 S152 S223 V224 L225 S231 F385 E386	E145-R227 IonicContact OE2-NH1 3.86Å; E145-R227 PolarHBondContact OE2-NH1 3.3Å; T149-R227 HydrophobicContact CG2-CB 4.31Å; S152-R227 PolarHBondContact OG-O 3.11Å; S152-R227 VanDerWaalsContact OG-O 3.08Å; S223-R227 VanDerWaalsContact O-CB 3.29Å; S223-R227 WeakPolarHBondContact O-CB 3.23Å; S223-R227 PolarHBondContact O-N 2.88Å; V224-R227 PolarHBondContact O-N 3.2Å; L225-R227 PolarHBondContact O-N 3.43Å; R227-S231 WeakPolarHBondContact O-CB 3.1Å; R227-S231 PolarHBondContact O-N 3.36Å; R227-S231 PolarHBondContact O-OG 3.12Å; R227-F385 HydrophobicContact CG-CB 4.35Å; R227-F385 HydrophobicContact CG-CD1 3.92Å; R227-F385 HydrophobicContact CG-CE1 4.5Å; R227-F385 HydrophobicContact CG-CG 4.2Å; R227-F385 PolarHBondContact NE-O 2.85Å; R227-F385 PolarHBondContact NH1-O 2.99Å; R227-F385 VanDerWaalsContact NH1-O 3.12Å; R227-F385 PolarHBondContact NH2-O 2.75Å; R227-E386 IonicContact CZ-OE1 3.75Å; R227-E386 IonicContact NE-OE1 2.69Å; R227-E386 IonicContact NH2-OE1 3.64Å; R227-E386 PolarHBondContact NH2-OE1 3.42Å
228	R	93.3	Very high	91.4	Very high	2 Å²	2	26.7 Å²	26.7	1%	0.008	13%	0.129	C	C	.	.	H	α-helix	trans	-62.8	-47.4	178.1	-69.9	-179.5	171.5	-173.9	-3.5	110.9	V224 L225 L226 S231 L232 F308 Y312 Y360 E386	V224-R228 HydrophobicContact CG1-CG 4.49Å; V224-R228 VanDerWaalsContact O-CG 3.27Å; V224-R228 WeakPolarHBondContact O-CG 3.3Å; V224-R228 PolarHBondContact O-N 3.31Å; L225-R228 PolarHBondContact O-N 3.28Å; L226-R228 VanDerWaalsContact C-N 3.33Å; L226-R228 PolarHBondContact O-N 2.86Å; R228-S231 PolarHBondContact O-N 3.22Å; R228-S231 PolarHBondContact O-OG 3.46Å; R228-L232 WeakPolarHBondContact O-CB 3.04Å; R228-L232 PolarHBondContact O-N 2.94Å; R228-F308 HydrophobicContact CB-CE1 4.07Å; R228-F308 HydrophobicContact CB-CZ 4.16Å; R228-Y312 WeakPolarHBondContact CD-OH 3.39Å; R228-Y312 PolarHBondContact NH1-OH 3.48Å; R228-Y360 HydrophobicContact CB-CE1 4.07Å; R228-Y360 HydrophobicContact CG-CE1 3.75Å; R228-Y360 WeakPolarHBondContact CG-OH 3.14Å; R228-E386 IonicContact CZ-OE2 2.99Å; R228-E386 IonicContact NE-OE1 3.28Å; R228-E386 PolarHBondContact NE-OE1 3.41Å; R228-E386 IonicContact NE-OE2 3.55Å; R228-E386 PolarHBondContact NE-OE2 3.18Å; R228-E386 IonicContact NH2-OE2 3.71Å; R228-E386 PolarHBondContact NH2-OE2 3.34Å
229	L	94.4	Very high	91.6	Very high	23 Å²	23	28.2 Å²	28.2	12%	0.12	14%	0.137	C	C	.	.	H	α-helix	trans	-58.4	-52.3	177.1	-177.7	77.7	0	0	0	111.6	W212 L225 L226 S231 L232 M233 M304 F308	W212-L229 HydrophobicContact CZ2-CD2 4.35Å; L225-L229 PolarHBondContact O-N 3.29Å; L226-L229 PolarHBondContact O-N 2.96Å; L229-S231 VanDerWaalsContact C-N 3.31Å; L229-S231 PolarHBondContact O-N 3.49Å; L229-L232 PolarHBondContact O-N 3.34Å; L229-M233 HydrophobicContact CD1-CG 4.15Å; L229-M233 HydrophobicContact CG-CG 4.23Å; L229-M233 VanDerWaalsContact O-CB 3.29Å; L229-M233 WeakPolarHBondContact O-CB 3.39Å; L229-M233 VanDerWaalsContact O-CG 3.28Å; L229-M233 WeakPolarHBondContact O-CG 3.46Å; L229-M233 PolarHBondContact O-N 3.28Å; L229-M304 HydrophobicContact CD1-CG 4.36Å; L229-F308 HydrophobicContact CB-CD1 4.43Å; L229-F308 HydrophobicContact CB-CE1 3.9Å; L229-F308 HydrophobicContact CB-CE2 4.4Å; L229-F308 HydrophobicContact CB-CZ 3.89Å; L229-F308 HydrophobicContact CD1-CD1 4.22Å; L229-F308 HydrophobicContact CD1-CD2 3.63Å; L229-F308 HydrophobicContact CD1-CE1 4.28Å; L229-F308 HydrophobicContact CD1-CE2 3.7Å; L229-F308 HydrophobicContact CD1-CG 3.89Å; L229-F308 HydrophobicContact CD1-CZ 4.04Å
230	C	94.2	Very high	91.8	Very high	11 Å²	11	28.6 Å²	28.6	7%	0.074	14%	0.138	C	C	.	.	H	α-helix	trans	-60	-40.8	179.6	-66.2	0	0	0	0	111.7	S152 V156 L226 G234	S152-C230 WeakPolarHBondContact O-CB 3.34Å; S152-C230 VanDerWaalsContact OG-CB 3.25Å; S152-C230 WeakPolarHBondContact OG-CB 3.16Å; V156-C230 HydrophobicContact CB-CB 4.1Å; V156-C230 HydrophobicContact CG1-CB 3.81Å; L226-C230 WeakPolarHBondContact O-CB 3.35Å; L226-C230 PolarHBondContact O-N 2.87Å; L226-C230 PolarHBondContact O-SG 2.89Å; C230-G234 PolarHBondContact O-N 2.89Å
231	S	92.7	Very high	92.2	Very high	4 Å²	4	22.8 Å²	22.8	3%	0.028	11%	0.113	C	C	.	.	H	α-helix	trans	-65.9	-43.2	178.5	78	0	0	0	0	112.7	S152 R227 R228 L229 T235 Y360	S152-S231 PolarHBondContact OG-N 2.98Å; R227-S231 WeakPolarHBondContact O-CB 3.1Å; R227-S231 PolarHBondContact O-N 3.36Å; R227-S231 PolarHBondContact O-OG 3.12Å; R228-S231 PolarHBondContact O-N 3.22Å; R228-S231 PolarHBondContact O-OG 3.46Å; L229-S231 VanDerWaalsContact C-N 3.31Å; L229-S231 PolarHBondContact O-N 3.49Å; S231-T235 WeakPolarHBondContact O-CB 3.27Å; S231-T235 PolarHBondContact O-N 3.06Å; S231-T235 PolarHBondContact O-OG1 3.23Å; S231-Y360 PolarHBondContact OG-OH 2.99Å
232	L	94.1	Very high	92.5	Very high	7 Å²	7	26.2 Å²	26.2	4%	0.037	13%	0.131	C	C	.	.	H	α-helix	trans	-70.9	-48	-179.9	-83.9	174.1	0	0	0	111.3	R228 L229 G234 T235 V236 M304 F308 L356 F357 Y360	R228-L232 WeakPolarHBondContact O-CB 3.04Å; R228-L232 PolarHBondContact O-N 2.94Å; L229-L232 PolarHBondContact O-N 3.34Å; L232-G234 PolarHBondContact O-N 2.88Å; L232-T235 PolarHBondContact O-N 3.19Å; L232-V236 VanDerWaalsContact O-CG2 3.24Å; L232-V236 WeakPolarHBondContact O-CG2 3.44Å; L232-V236 PolarHBondContact O-N 3.21Å; L232-M304 HydrophobicContact CB-CE 3.91Å; L232-M304 HydrophobicContact CB-SD 4.2Å; L232-M304 HydrophobicContact CD1-SD 4.32Å; L232-F308 HydrophobicContact CD1-CE2 3.79Å; L232-F308 HydrophobicContact CD1-CZ 3.8Å; L232-L356 HydrophobicContact CD2-CB 4.47Å; L232-F357 HydrophobicContact CD1-CD2 4.21Å; L232-Y360 HydrophobicContact CD1-CD1 4.01Å; L232-Y360 HydrophobicContact CD1-CD2 4.34Å; L232-Y360 HydrophobicContact CD1-CG 3.91Å; L232-Y360 HydrophobicContact CD2-CD2 3.76Å; L232-Y360 HydrophobicContact CD2-CG 3.87Å; L232-Y360 HydrophobicContact CG-CD1 4.44Å; L232-Y360 HydrophobicContact CG-CD2 3.9Å; L232-Y360 HydrophobicContact CG-CE2 4.31Å; L232-Y360 HydrophobicContact CG-CG 3.98Å
233	M	94.8	Very high	92.6	Very high	18 Å²	18	22.7 Å²	22.7	9%	0.089	12%	0.122	C	C	.	.	H	α-helix	trans	-58.7	-48.7	176.1	-72.2	-62.2	-70.2	0	0	111.4	V156 F160 L229 T235 V236 F237 V301 M304	V156-M233 HydrophobicContact CG2-CB 4.06Å; F160-M233 HydrophobicContact CZ-CB 4.43Å; F160-M233 HydrophobicContact CZ-CE 4.13Å; L229-M233 HydrophobicContact CD1-CG 4.15Å; L229-M233 HydrophobicContact CG-CG 4.23Å; L229-M233 VanDerWaalsContact O-CB 3.29Å; L229-M233 WeakPolarHBondContact O-CB 3.39Å; L229-M233 VanDerWaalsContact O-CG 3.28Å; L229-M233 WeakPolarHBondContact O-CG 3.46Å; L229-M233 PolarHBondContact O-N 3.28Å; M233-T235 VanDerWaalsContact C-N 3.35Å; M233-T235 PolarHBondContact O-N 3.47Å; M233-V236 PolarHBondContact O-N 3.23Å; M233-F237 HydrophobicContact CE-CD2 4.04Å; M233-F237 HydrophobicContact CE-CE2 3.44Å; M233-F237 VanDerWaalsContact CE-CE2 3.44Å; M233-F237 HydrophobicContact CE-CZ 4.31Å; M233-F237 WeakPolarHBondContact O-CB 3.45Å; M233-F237 WeakPolarHBondContact O-CD2 3.4Å; M233-F237 PolarHBondContact O-N 2.73Å; M233-F237 HydrophobicContact SD-CE2 4.48Å; M233-V301 HydrophobicContact CE-CB 4.42Å; M233-V301 HydrophobicContact CE-CG2 3.65Å; M233-M304 HydrophobicContact CG-CG 4.33Å; M233-M304 HydrophobicContact SD-CB 3.83Å; M233-M304 HydrophobicContact SD-CE 4.34Å; M233-M304 HydrophobicContact SD-CG 3.63Å
234	G	93.8	Very high	92.7	Very high	0 Å²	0	22.3 Å²	22.3	0%	0	12%	0.119	C	C	.	.	H	α-helix	trans	-61.9	-40.2	179	0	0	0	0	0	112.9	Y155 C230 L232 M238	Y155-G234 PolarHBondContact OH-O 3.5Å; C230-G234 PolarHBondContact O-N 2.89Å; L232-G234 PolarHBondContact O-N 2.88Å; G234-M238 VanDerWaalsContact O-CB 3.28Å; G234-M238 WeakPolarHBondContact O-CB 3.41Å; G234-M238 PolarHBondContact O-N 3.01Å
235	T	93.6	Very high	92.6	Very high	56 Å²	56	27.1 Å²	27.1	34%	0.344	14%	0.14	S	C	.	.	H	α-helix	trans	-65.3	-45.5	178.8	-56.8	0	0	0	0	111.6	S231 L232 M233 M238 L239	S231-T235 WeakPolarHBondContact O-CB 3.27Å; S231-T235 PolarHBondContact O-N 3.06Å; S231-T235 PolarHBondContact O-OG1 3.23Å; L232-T235 PolarHBondContact O-N 3.19Å; M233-T235 VanDerWaalsContact C-N 3.35Å; M233-T235 PolarHBondContact O-N 3.47Å; T235-M238 PolarHBondContact O-N 2.64Å; T235-L239 PolarHBondContact O-N 2.82Å; T235-L239 VanDerWaalsContact O-N 3.14Å
236	V	94.6	Very high	92.5	Very high	0 Å²	0	32.1 Å²	32.1	0%	0	17%	0.17	C	C	.	.	H	α-helix	trans	-65.7	-43.8	-179.9	175.9	0	0	0	0	111.2	L232 M233 L239 R240 F295 V300 M304 L356	L232-V236 VanDerWaalsContact O-CG2 3.24Å; L232-V236 WeakPolarHBondContact O-CG2 3.44Å; L232-V236 PolarHBondContact O-N 3.21Å; M233-V236 PolarHBondContact O-N 3.23Å; V236-L239 WeakPolarHBondContact O-CB 3.34Å; V236-L239 PolarHBondContact O-N 2.92Å; V236-R240 PolarHBondContact O-N 3.43Å; V236-F295 HydrophobicContact CG1-CE1 3.37Å; V236-F295 HydrophobicContact CG1-CZ 3.5Å; V236-V300 HydrophobicContact CB-CG1 4.28Å; V236-V300 HydrophobicContact CG1-CB 4.35Å; V236-V300 HydrophobicContact CG1-CG1 3.44Å; V236-V300 VanDerWaalsContact CG1-CG1 3.44Å; V236-V300 HydrophobicContact CG1-CG2 3.89Å; V236-M304 HydrophobicContact CG2-CE 3.9Å; V236-L356 HydrophobicContact CG2-CD1 3.5Å; V236-L356 VanDerWaalsContact CG2-CD1 3.5Å
237	F	94.1	Very high	92.3	Very high	14 Å²	14	32 Å²	32	6%	0.061	17%	0.172	C	C	.	.	H	α-helix	trans	-71.1	-30.7	177.9	-86.7	-100	0	0	0	112.9	V159 F160 T163 M233 R240 C241 V300 V301	V159-F237 HydrophobicContact CG1-CB 3.64Å; F160-F237 HydrophobicContact CD1-CD1 4.19Å; F160-F237 HydrophobicContact CD1-CG 4.25Å; F160-F237 HydrophobicContact CE1-CB 4.4Å; F160-F237 HydrophobicContact CE1-CD1 4.05Å; F160-F237 AromaticContact CE1-CD2 3.9Å; F160-F237 HydrophobicContact CE1-CD2 3.9Å; F160-F237 HydrophobicContact CE1-CE1 4.28Å; F160-F237 HydrophobicContact CE1-CE2 4.14Å; F160-F237 AromaticContact CE1-CG 3.84Å; F160-F237 HydrophobicContact CE1-CG 3.84Å; F160-F237 HydrophobicContact CE1-CZ 4.32Å; T163-F237 HydrophobicContact CG2-CD1 4.04Å; M233-F237 HydrophobicContact CE-CD2 4.04Å; M233-F237 HydrophobicContact CE-CE2 3.44Å; M233-F237 VanDerWaalsContact CE-CE2 3.44Å; M233-F237 HydrophobicContact CE-CZ 4.31Å; M233-F237 WeakPolarHBondContact O-CB 3.45Å; M233-F237 WeakPolarHBondContact O-CD2 3.4Å; M233-F237 PolarHBondContact O-N 2.73Å; M233-F237 HydrophobicContact SD-CE2 4.48Å; F237-R240 VanDerWaalsContact O-CB 3.26Å; F237-R240 WeakPolarHBondContact O-CB 3.46Å; F237-R240 PolarHBondContact O-N 3.49Å; F237-C241 PolarHBondContact O-N 3.49Å; F237-C241 PolarHBondContact O-SG 2.99Å; F237-V300 HydrophobicContact CD2-CG1 4.31Å; F237-V300 HydrophobicContact CE2-CB 4.38Å; F237-V300 HydrophobicContact CE2-CG1 3.78Å; F237-V301 HydrophobicContact CE2-CG2 4.03Å; F237-V301 HydrophobicContact CZ-CG2 3.78Å
238	M	93.8	Very high	91.9	Very high	49 Å²	49	33.4 Å²	33.4	24%	0.241	18%	0.182	C	C	.	.	H	α-helix	trans	-63.7	-43	171.9	-172	63.8	76.8	0	0	111.4	Y155 V159 F162 G234 T235 R240 C241 I242	Y155-M238 HydrophobicContact CE2-CE 4.38Å; V159-M238 HydrophobicContact CG1-CB 4.4Å; V159-M238 HydrophobicContact CG2-CE 3.61Å; F162-M238 HydrophobicContact CD1-SD 4.16Å; F162-M238 HydrophobicContact CE1-SD 4.2Å; G234-M238 VanDerWaalsContact O-CB 3.28Å; G234-M238 WeakPolarHBondContact O-CB 3.41Å; G234-M238 PolarHBondContact O-N 3.01Å; T235-M238 PolarHBondContact O-N 2.64Å; M238-R240 VanDerWaalsContact C-N 3.29Å; M238-R240 PolarHBondContact O-N 2.87Å; M238-C241 WeakPolarHBondContact O-CB 3.16Å; M238-C241 PolarHBondContact O-N 3.23Å; M238-I242 HydrophobicContact CG-CD1 4.48Å; M238-I242 WeakPolarHBondContact O-CG1 3.2Å; M238-I242 PolarHBondContact O-N 3.32Å; M238-I242 VanDerWaalsContact O-N 3.14Å
239	L	92.8	Very high	91.5	Very high	69 Å²	69	35.1 Å²	35.1	36%	0.361	19%	0.191	S	C	.	.	H	α-helix	trans	-60.6	-40.6	173.5	179.5	63.4	0	0	0	111.2	T235 V236 I242 T243 I352	T235-L239 PolarHBondContact O-N 2.82Å; T235-L239 VanDerWaalsContact O-N 3.14Å; V236-L239 WeakPolarHBondContact O-CB 3.34Å; V236-L239 PolarHBondContact O-N 2.92Å; L239-I242 PolarHBondContact O-N 3.27Å; L239-T243 HydrophobicContact CD1-CG2 4.19Å; L239-T243 HydrophobicContact CG-CG2 4.44Å; L239-T243 WeakPolarHBondContact O-CB 3.4Å; L239-T243 WeakPolarHBondContact O-CG2 3.47Å; L239-T243 PolarHBondContact O-N 2.88Å; L239-T243 PolarHBondContact O-OG1 3.34Å; L239-I352 HydrophobicContact CD2-CD1 4.19Å; L239-I352 HydrophobicContact CD2-CG2 4.16Å
240	R	92.4	Very high	91.1	Very high	11 Å²	11	34.4 Å²	34.4	4%	0.042	19%	0.188	C	C	.	.	H	α-helix	trans	-56.4	-48.4	172.9	-169.9	178.3	-167.5	-148.9	-4.6	111.9	V236 F237 M238 I242 T243 M244 D292 F295 G297	V236-R240 PolarHBondContact O-N 3.43Å; F237-R240 VanDerWaalsContact O-CB 3.26Å; F237-R240 WeakPolarHBondContact O-CB 3.46Å; F237-R240 PolarHBondContact O-N 3.49Å; M238-R240 VanDerWaalsContact C-N 3.29Å; M238-R240 PolarHBondContact O-N 2.87Å; R240-I242 VanDerWaalsContact C-N 3.35Å; R240-I242 PolarHBondContact O-N 3.19Å; R240-T243 VanDerWaalsContact CA-OG1 3.32Å; R240-T243 WeakPolarHBondContact CA-OG1 3.28Å; R240-T243 PolarHBondContact O-N 3.09Å; R240-T243 PolarHBondContact O-OG1 3.23Å; R240-M244 HydrophobicContact CG-CE 3.52Å; R240-M244 HydrophobicContact CG-CG 4.3Å; R240-M244 HydrophobicContact CG-SD 3.74Å; R240-M244 VanDerWaalsContact CZ-CE 3.45Å; R240-M244 WeakPolarHBondContact O-CB 3.48Å; R240-M244 VanDerWaalsContact O-CG 3.26Å; R240-M244 WeakPolarHBondContact O-CG 3.17Å; R240-M244 PolarHBondContact O-N 2.74Å; R240-D292 IonicContact CZ-OD2 2.86Å; R240-D292 PolarHBondContact NH2-O 2.91Å; R240-D292 IonicContact NH2-OD2 3.19Å; R240-D292 PolarHBondContact NH2-OD2 3.29Å; R240-F295 HydrophobicContact CB-CD1 3.66Å; R240-F295 HydrophobicContact CB-CE1 4.26Å; R240-F295 HydrophobicContact CG-CB 4.26Å; R240-F295 HydrophobicContact CG-CD1 3.74Å; R240-F295 HydrophobicContact CG-CG 4.5Å; R240-F295 PolarHBondContact NE-O 3.27Å; R240-F295 PolarHBondContact NH2-O 3.07Å; R240-G297 VanDerWaalsContact CZ-CA 3.41Å; R240-G297 VanDerWaalsContact NH2-N 3.11Å
241	C	92.1	Very high	90.6	Very high	2 Å²	2	34 Å²	34	1%	0.014	19%	0.186	C	C	.	.	H	α-helix	trans	-58.4	-46.4	178.7	-66	0	0	0	0	112.3	F162 T163 V166 F237 M238 F245	F162-C241 HydrophobicContact CD1-CB 3.92Å; F162-C241 HydrophobicContact CE1-CB 3.64Å; T163-C241 WeakPolarHBondContact CA-SG 3.28Å; T163-C241 PolarHBondContact OG1-SG 3.47Å; V166-C241 HydrophobicContact CG1-CB 4.49Å; V166-C241 HydrophobicContact CG2-CB 4.23Å; F237-C241 PolarHBondContact O-N 3.49Å; F237-C241 PolarHBondContact O-SG 2.99Å; M238-C241 WeakPolarHBondContact O-CB 3.16Å; M238-C241 PolarHBondContact O-N 3.23Å; C241-F245 VanDerWaalsContact O-CB 3.24Å; C241-F245 WeakPolarHBondContact O-CB 3.36Å; C241-F245 PolarHBondContact O-N 3.33Å; C241-F245 VanDerWaalsContact O-N 3.07Å
242	I	91.6	Very high	90	Very high	96 Å²	96	34.4 Å²	34.4	49%	0.492	19%	0.188	S	C	.	.	H	α-helix	trans	-63.9	-48.2	-179.8	-64.9	168	0	0	0	110.2	M238 L239 R240 F245 V246	M238-I242 HydrophobicContact CG-CD1 4.48Å; M238-I242 WeakPolarHBondContact O-CG1 3.2Å; M238-I242 PolarHBondContact O-N 3.32Å; M238-I242 VanDerWaalsContact O-N 3.14Å; L239-I242 PolarHBondContact O-N 3.27Å; R240-I242 VanDerWaalsContact C-N 3.35Å; R240-I242 PolarHBondContact O-N 3.19Å; I242-F245 PolarHBondContact O-N 2.93Å; I242-V246 HydrophobicContact CG2-CG2 4.31Å; I242-V246 WeakPolarHBondContact O-CB 3.34Å; I242-V246 WeakPolarHBondContact O-CG2 3.32Å; I242-V246 PolarHBondContact O-N 3.32Å
243	T	91.3	Very high	89.1	Confident	36 Å²	36	34.4 Å²	34.4	22%	0.221	19%	0.19	C	C	.	.	H	α-helix	trans	-61.6	-51.2	-178.2	47	0	0	0	0	111.5	L239 R240 F245 V246 T247 M294	L239-T243 HydrophobicContact CD1-CG2 4.19Å; L239-T243 HydrophobicContact CG-CG2 4.44Å; L239-T243 WeakPolarHBondContact O-CB 3.4Å; L239-T243 WeakPolarHBondContact O-CG2 3.47Å; L239-T243 PolarHBondContact O-N 2.88Å; L239-T243 PolarHBondContact O-OG1 3.34Å; R240-T243 VanDerWaalsContact CA-OG1 3.32Å; R240-T243 WeakPolarHBondContact CA-OG1 3.28Å; R240-T243 PolarHBondContact O-N 3.09Å; R240-T243 PolarHBondContact O-OG1 3.23Å; T243-F245 VanDerWaalsContact C-N 3.29Å; T243-F245 PolarHBondContact O-N 3.36Å; T243-V246 PolarHBondContact O-N 3.02Å; T243-V246 VanDerWaalsContact O-N 3.16Å; T243-T247 PolarHBondContact O-N 3.46Å; T243-M294 VanDerWaalsContact C-CE 3.41Å; T243-M294 VanDerWaalsContact CB-CE 3.48Å; T243-M294 HydrophobicContact CG2-CE 4.23Å; T243-M294 WeakPolarHBondContact O-CE 3.45Å
244	M	88.4	Confident	87.8	Confident	2 Å²	2	41.6 Å²	41.6	1%	0.01	22%	0.223	C	C	.	.	H	α-helix	trans	-60.3	-36.8	177.9	-69.4	-179.1	168.1	0	0	113.8	M167 V170 R240 T247 D292 M294 F295	M167-M244 HydrophobicContact CE-CE 4.1Å; M167-M244 HydrophobicContact CE-SD 3.76Å; M167-M244 HydrophobicContact SD-SD 3.72Å; V170-M244 HydrophobicContact CG2-CB 4.17Å; V170-M244 WeakPolarHBondContact CG2-O 3.23Å; R240-M244 HydrophobicContact CG-CE 3.52Å; R240-M244 HydrophobicContact CG-CG 4.3Å; R240-M244 HydrophobicContact CG-SD 3.74Å; R240-M244 VanDerWaalsContact CZ-CE 3.45Å; R240-M244 WeakPolarHBondContact O-CB 3.48Å; R240-M244 VanDerWaalsContact O-CG 3.26Å; R240-M244 WeakPolarHBondContact O-CG 3.17Å; R240-M244 PolarHBondContact O-N 2.74Å; M244-T247 CarbonylContact O-C 3.5Å; M244-D292 HydrophobicContact CE-CB 3.64Å; M244-D292 VanDerWaalsContact CE-O 3.23Å; M244-D292 WeakPolarHBondContact CE-O 3.49Å; M244-D292 HydrophobicContact SD-CB 3.95Å; M244-M294 WeakPolarHBondContact CE-O 3.45Å; M244-M294 VanDerWaalsContact CG-O 3.3Å; M244-M294 WeakPolarHBondContact CG-O 3.49Å; M244-F295 VanDerWaalsContact CE-O 3.31Å; M244-F295 WeakPolarHBondContact CE-O 3.46Å
245	F	88.3	Confident	86.6	Confident	105 Å²	105	44.4 Å²	44.4	46%	0.461	24%	0.236	S	C	.	.	H	α-helix	trans	-69.4	-39.3	177.4	-177.7	-90.4	0	0	0	112	V166 I169 C241 I242 T243	V166-F245 HydrophobicContact CG1-CB 4.43Å; I169-F245 HydrophobicContact CG2-CE2 4.46Å; C241-F245 VanDerWaalsContact O-CB 3.24Å; C241-F245 WeakPolarHBondContact O-CB 3.36Å; C241-F245 PolarHBondContact O-N 3.33Å; C241-F245 VanDerWaalsContact O-N 3.07Å; I242-F245 PolarHBondContact O-N 2.93Å; T243-F245 VanDerWaalsContact C-N 3.29Å; T243-F245 PolarHBondContact O-N 3.36Å
246	V	89.9	Confident	85.5	Confident	104 Å²	104	42.7 Å²	42.7	63%	0.63	23%	0.225	S	C	*	.	H	α-helix	trans	-71	-37	179.7	170.4	0	0	0	0	111.5	I242 T243	I242-V246 HydrophobicContact CG2-CG2 4.31Å; I242-V246 WeakPolarHBondContact O-CB 3.34Å; I242-V246 WeakPolarHBondContact O-CG2 3.32Å; I242-V246 PolarHBondContact O-N 3.32Å; T243-V246 PolarHBondContact O-N 3.02Å; T243-V246 VanDerWaalsContact O-N 3.16Å
247	T	86.4	Confident	84.2	Confident	61 Å²	61	51.9 Å²	51.9	37%	0.374	27%	0.268	S	S	.	.			trans	-140.9	118.1	-179.1	-50.7	0	0	0	0	111	T243 M244 L249 M294	T243-T247 PolarHBondContact O-N 3.46Å; M244-T247 CarbonylContact O-C 3.5Å; T247-L249 HydrophobicContact CG2-CD2 4.2Å; T247-M294 HydrophobicContact CG2-SD 4.39Å
248	S	83.1	Confident	83.1	Confident	31 Å²	31	52.2 Å²	52.2	22%	0.217	27%	0.272	C	S	.	.	P	Polyproline II helix	trans	-102	121.5	174.1	-50.1	0	0	0	0	109.2
249	L	85.4	Confident	81.5	Confident	39 Å²	39	53.4 Å²	53.4	20%	0.204	29%	0.285	C	S	.	.	P	Polyproline II helix	trans	-91	160	-178.8	-61.8	175.9	0	0	0	111.5	T247 M294 Y342	T247-L249 HydrophobicContact CG2-CD2 4.2Å; L249-M294 HydrophobicContact CD1-CB 4.18Å; L249-Y342 HydrophobicContact CB-CE2 4.42Å; L249-Y342 HydrophobicContact CD1-CD2 4.49Å
250	S	85.1	Confident	79.8	Confident	7 Å²	7	51.7 Å²	51.7	5%	0.049	28%	0.283	C	S	.	.	P	Polyproline II helix	trans	-69.2	155.4	172.8	63.2	0	0	0	0	111.3	P181 L183 Y342	P181-S250 PolarHBondContact O-OG 2.74Å; L183-S250 WeakPolarHBondContact CD1-OG 3.34Å; S250-Y342 VanDerWaalsContact O-CE2 3.25Å; S250-Y342 WeakPolarHBondContact O-CE2 3.24Å; S250-Y342 PolarHBondContact O-OH 2.73Å; S250-Y342 PolarHBondContact OG-OH 3.37Å
251	V	85.4	Confident	78.1	Confident	4 Å²	4	60.6 Å²	60.6	2%	0.024	32%	0.323	C	S	.	.	P	Polyproline II helix	trans	-65.6	131.9	-176.8	-178.7	0	0	0	0	110.7	V174 M177 P182 G253 L256 C258 Y293	V174-V251 HydrophobicContact CG1-CG2 3.64Å; M177-V251 HydrophobicContact CE-CB 4.15Å; M177-V251 HydrophobicContact CE-CG1 4.01Å; M177-V251 HydrophobicContact CG-CB 4.31Å; M177-V251 HydrophobicContact CG-CG2 3.99Å; M177-V251 HydrophobicContact SD-CB 4.48Å; M177-V251 HydrophobicContact SD-CG2 4.2Å; P182-V251 WeakPolarHBondContact CB-O 3.36Å; P182-V251 WeakPolarHBondContact CG-O 3.47Å; V251-G253 VanDerWaalsContact C-N 3.31Å; V251-G253 VanDerWaalsContact CG1-O 3.31Å; V251-G253 WeakPolarHBondContact CG1-O 3.22Å; V251-G253 PolarHBondContact O-N 2.99Å; V251-L256 HydrophobicContact CG1-CB 3.9Å; V251-L256 HydrophobicContact CG1-CD1 4.17Å; V251-C258 HydrophobicContact CG2-CB 4.47Å; V251-Y293 HydrophobicContact CB-CE2 4.2Å; V251-Y293 WeakPolarHBondContact CG1-OH 3.4Å; V251-Y293 HydrophobicContact CG2-CE2 3.94Å
252	P	79.5	Confident	76.4	Confident	11 Å²	11	65.3 Å²	65.3	7%	0.071	35%	0.347	C	S	.	.	S	Bend	trans	-73.1	-18.9	-175.6	27.1	-33.6	0	0	0	114.1	L188 Y293 E340 Y342	L188-P252 HydrophobicContact CD1-CB 4.28Å; P252-Y293 VanDerWaalsContact CD-CZ 3.46Å; P252-Y293 HydrophobicContact CG-CD1 3.97Å; P252-Y293 HydrophobicContact CG-CE1 3.89Å; P252-E340 WeakPolarHBondContact CG-O 3.35Å; P252-Y342 HydrophobicContact CB-CD1 4.16Å; P252-Y342 HydrophobicContact CB-CD2 4.32Å; P252-Y342 HydrophobicContact CB-CE1 3.87Å; P252-Y342 HydrophobicContact CB-CE2 4.04Å; P252-Y342 HydrophobicContact CB-CG 4.37Å
253	G	74.5	Confident	74.9	Confident	8 Å²	8	63.7 Å²	63.7	8%	0.082	34%	0.335	C	S	.	.			trans	-142.2	138.1	-178.2	0	0	0	0	0	113.7	V251 H255 L256	V251-G253 VanDerWaalsContact C-N 3.31Å; V251-G253 VanDerWaalsContact CG1-O 3.31Å; V251-G253 WeakPolarHBondContact CG1-O 3.22Å; V251-G253 PolarHBondContact O-N 2.99Å; G253-H255 PolarHBondContact O-N 3.46Å; G253-H255 VanDerWaalsContact O-N 3.11Å; G253-L256 PolarHBondContact O-N 3.36Å
254	Q	68.4	Low	73.6	Confident	169 Å²	169	65.5 Å²	65.5	79%	0.79	36%	0.361	S	S	*	.	T	Hydrogen-bonded Turn	trans	-64.6	-14.8	176.4	-65.8	-177.1	-10.4	0	0	113.7	L256	Q254-L256 VanDerWaalsContact C-N 3.32Å
255	H	69	Low	73.3	Confident	58 Å²	58	71.1 Å²	71.1	27%	0.269	39%	0.391	S	S	.	.	T	Hydrogen-bonded Turn	trans	-75.5	-18.9	179.9	68	-95.5	0	0	0	113.6	R193 G253 Q257 H339	R193-H255 VanDerWaalsContact CZ-NE2 3.33Å; R193-H255 PolarHBondContact NE-CD2 3.29Å; R193-H255 PolarHBondContact NE-CE1 3.3Å; R193-H255 VanDerWaalsContact NE-CE1 3.26Å; R193-H255 PolarHBondContact NE-ND1 3.15Å; R193-H255 PolarHBondContact NE-NE2 2.94Å; R193-H255 PolarHBondContact NH1-CD2 3.49Å; R193-H255 PolarHBondContact NH2-CD2 3.45Å; R193-H255 PolarHBondContact NH2-NE2 3.31Å; G253-H255 PolarHBondContact O-N 3.46Å; G253-H255 VanDerWaalsContact O-N 3.11Å; H255-Q257 PolarHBondContact O-N 3.32Å; H255-H339 PolarHBondContact CE1-O 2.95Å
256	L	70.3	Confident	73	Confident	20 Å²	20	72.4 Å²	72.4	11%	0.105	40%	0.4	C	S	.	.	S	Bend	trans	-82.9	104.1	172.4	-68.8	97.7	0	0	0	108.2	M177 V251 G253 Q254 C258	M177-L256 WeakPolarHBondContact CE-O 3.33Å; V251-L256 HydrophobicContact CG1-CB 3.9Å; V251-L256 HydrophobicContact CG1-CD1 4.17Å; G253-L256 PolarHBondContact O-N 3.36Å; Q254-L256 VanDerWaalsContact C-N 3.32Å; L256-C258 VanDerWaalsContact C-N 3.32Å; L256-C258 PolarHBondContact O-N 2.97Å
257	Q	66.1	Low	72.8	Confident	193 Å²	193	76.9 Å²	76.9	90%	0.902	41%	0.406	S	S	*	.			trans	-77.5	84.3	173.7	-67.9	-167.3	-3.1	0	0	110.2	H255	H255-Q257 PolarHBondContact O-N 3.32Å
258	C	71.1	Confident	72.6	Confident	22 Å²	22	75.7 Å²	75.7	15%	0.149	40%	0.402	C	S	.	.			trans	-89.8	105.7	177.1	-50.9	0	0	0	0	109.6	M177 V251 L256 C290	M177-C258 HydrophobicContact SD-CB 4.33Å; V251-C258 HydrophobicContact CG2-CB 4.47Å; L256-C258 VanDerWaalsContact C-N 3.32Å; L256-C258 PolarHBondContact O-N 2.97Å; C258-C290 HydrophobicContact CB-CB 3.66Å; C258-C290 WeakPolarHBondContact CB-SG 3.27Å; C258-C290 WeakPolarHBondContact SG-CB 3.12Å; C258-C290 CovalentContact SG-SG 2.01Å; C258-C290 PolarHBondContact SG-SG 3.5Å
259	S	60.3	Low	72.7	Confident	74 Å²	74	76 Å²	76	52%	0.517	40%	0.399	S	S	.	.			trans	-92.9	103.8	173.6	-173.1	0	0	0	0	110.1	K261	S259-K261 PolarHBondContact O-N 2.86Å
260	G	57.5	Low	72.8	Confident	32 Å²	32	77.7 Å²	77.7	33%	0.33	41%	0.408	S	S	.	.	S	Bend	trans	-71.3	13.3	-169.2	0	0	0	0	0	117.4
261	K	55.9	Low	72.9	Confident	199 Å²	199	83.4 Å²	83.4	87%	0.865	43%	0.434	S	S	*	.			trans	-145.5	56.2	-171.3	-66.1	-172.2	-179.9	178	0	115.1	S259	S259-K261 PolarHBondContact O-N 2.86Å
262	I	56.4	Low	72.7	Confident	101 Å²	101	86 Å²	86	52%	0.518	44%	0.443	S	S	.	.			trans	-106.4	-18.3	-177.8	-59.3	-178.8	0	0	0	114.1
263	Y	60.8	Low	73	Confident	61 Å²	61	85.6 Å²	85.6	24%	0.239	44%	0.441	C	S	.	.			trans	-124.2	97.3	-171	-51.2	-74.8	0	0	0	113.7	A268 K269 R272	Y263-A268 HydrophobicContact CD1-CB 4Å; Y263-K269 WeakPolarHBondContact O-CE 3.3Å; Y263-R272 VanDerWaalsContact CZ-NH1 3.29Å; Y263-R272 PolarHBondContact OH-NH1 2.69Å
264	G	64.3	Low	73.6	Confident	75 Å²	75	89.2 Å²	89.2	77%	0.773	46%	0.458	S	S	*	.			trans	-73	-38.2	173.3	0	0	0	0	0	113.3
265	D	82.7	Confident	74.5	Confident	120 Å²	120	83.3 Å²	83.3	64%	0.642	44%	0.438	S	S	*	.	S	Bend	trans	-94.7	137	-171.3	-69.8	-26.1	0	0	0	113.5	W267 A268 K269	D265-W267 PolarHBondContact O-N 3.44Å; D265-A268 HydrophobicContact CB-CB 4.38Å; D265-A268 WeakPolarHBondContact O-CB 3.36Å; D265-A268 PolarHBondContact O-N 3.36Å; D265-K269 PolarHBondContact O-N 2.95Å; D265-K269 VanDerWaalsContact O-N 3.17Å
266	M	81.9	Confident	75.2	Confident	131 Å²	131	80.9 Å²	80.9	65%	0.645	43%	0.427	S	S	*	.	H	α-helix	trans	-55.3	-35.4	174.9	-174.9	64	73.9	0	0	112.3	F165 K269 L270	F165-M266 HydrophobicContact CE2-SD 4.39Å; F165-M266 HydrophobicContact CZ-SD 4.43Å; M266-K269 PolarHBondContact O-N 3.41Å; M266-L270 PolarHBondContact O-N 3.44Å
267	W	84.6	Confident	76	Confident	198 Å²	198	84.6 Å²	84.6	75%	0.75	44%	0.44	S	S	*	.	H	α-helix	trans	-66.2	-40.5	177.9	-170.5	-106.5	0	0	0	112.6	D265 K269 L270 H271	D265-W267 PolarHBondContact O-N 3.44Å; W267-K269 VanDerWaalsContact C-N 3.32Å; W267-K269 PolarHBondContact O-N 3.49Å; W267-L270 HydrophobicContact CE3-CD2 4.36Å; W267-L270 HydrophobicContact CZ3-CD2 4.22Å; W267-L270 PolarHBondContact O-N 2.89Å; W267-H271 PolarHBondContact O-N 3.09Å
268	A	83.4	Confident	76.9	Confident	36 Å²	36	79.8 Å²	79.8	30%	0.298	43%	0.428	S	S	.	.	H	α-helix	trans	-66	-37.2	176.4	0	0	0	0	0	111.5	Y263 D265 H271 R272	Y263-A268 HydrophobicContact CD1-CB 4Å; D265-A268 HydrophobicContact CB-CB 4.38Å; D265-A268 WeakPolarHBondContact O-CB 3.36Å; D265-A268 PolarHBondContact O-N 3.36Å; A268-H271 PolarHBondContact O-N 3.26Å; A268-R272 PolarHBondContact O-N 3.01Å
269	K	84.6	Confident	77.4	Confident	38 Å²	38	79.1 Å²	79.1	17%	0.165	42%	0.424	C	S	.	.	H	α-helix	trans	-63.2	-44.5	173.5	-61.8	-177.5	-165.4	-161.6	0	111.7	V168 E172 Y263 D265 M266 W267 R272 A273	V168-K269 HydrophobicContact CG1-CB 3.98Å; V168-K269 HydrophobicContact CG1-CG 4.18Å; E172-K269 VanDerWaalsContact CD-NZ 3.32Å; E172-K269 WeakPolarHBondContact OE1-CE 3.39Å; E172-K269 IonicContact OE1-NZ 2.65Å; E172-K269 PolarHBondContact OE1-NZ 3.14Å; E172-K269 WeakPolarHBondContact OE2-CE 3.12Å; E172-K269 IonicContact OE2-NZ 3.79Å; E172-K269 PolarHBondContact OE2-NZ 3.3Å; Y263-K269 WeakPolarHBondContact O-CE 3.3Å; D265-K269 PolarHBondContact O-N 2.95Å; D265-K269 VanDerWaalsContact O-N 3.17Å; M266-K269 PolarHBondContact O-N 3.41Å; W267-K269 VanDerWaalsContact C-N 3.32Å; W267-K269 PolarHBondContact O-N 3.49Å; K269-R272 PolarHBondContact O-N 3.43Å; K269-A273 WeakPolarHBondContact O-CB 3.2Å; K269-A273 PolarHBondContact O-N 2.97Å
270	L	86.6	Confident	78.4	Confident	74 Å²	74	83.5 Å²	83.5	39%	0.387	43%	0.434	S	S	.	.	H	α-helix	trans	-63.7	-42.2	177	-172.9	64.2	0	0	0	111.5	M266 W267 R272 A273 L274	M266-L270 PolarHBondContact O-N 3.44Å; W267-L270 HydrophobicContact CE3-CD2 4.36Å; W267-L270 HydrophobicContact CZ3-CD2 4.22Å; W267-L270 PolarHBondContact O-N 2.89Å; L270-R272 PolarHBondContact O-N 2.94Å; L270-A273 PolarHBondContact O-N 3.3Å; L270-L274 HydrophobicContact CG-CD1 4.33Å; L270-L274 WeakPolarHBondContact O-CB 3.26Å; L270-L274 WeakPolarHBondContact O-CG 3.21Å; L270-L274 PolarHBondContact O-N 3.17Å
271	H	86.6	Confident	79.2	Confident	127 Å²	127	83.1 Å²	83.1	59%	0.588	43%	0.43	S	S	*	.	H	α-helix	trans	-63.7	-40.5	177.4	-163.3	-28.8	0	0	0	112	W267 A268 L274 A275	W267-H271 PolarHBondContact O-N 3.09Å; A268-H271 PolarHBondContact O-N 3.26Å; H271-L274 PolarHBondContact O-N 3.3Å; H271-A275 PolarHBondContact O-N 3.27Å
272	R	83	Confident	80.4	Confident	58 Å²	58	76 Å²	76	22%	0.219	40%	0.4	C	S	.	.	H	α-helix	trans	-67.5	-40.6	174.1	-174.1	166.4	178.3	163.3	-4.7	111.7	V168 Y263 A268 K269 L270 L274 A275 I276 H288	V168-R272 HydrophobicContact CG2-CB 4.38Å; V168-R272 HydrophobicContact CG2-CG 4.18Å; Y263-R272 VanDerWaalsContact CZ-NH1 3.29Å; Y263-R272 PolarHBondContact OH-NH1 2.69Å; A268-R272 PolarHBondContact O-N 3.01Å; K269-R272 PolarHBondContact O-N 3.43Å; L270-R272 PolarHBondContact O-N 2.94Å; R272-L274 VanDerWaalsContact C-N 3.31Å; R272-L274 PolarHBondContact O-N 3.5Å; R272-A275 WeakPolarHBondContact O-CB 3.19Å; R272-A275 PolarHBondContact O-N 3.39Å; R272-I276 HydrophobicContact CG-CD1 4.07Å; R272-I276 VanDerWaalsContact O-CG1 3.3Å; R272-I276 WeakPolarHBondContact O-CG1 3.46Å; R272-I276 PolarHBondContact O-N 2.66Å; R272-H288 PolarHBondContact NH2-O 3.08Å
273	A	85.9	Confident	81.4	Confident	4 Å²	4	72.1 Å²	72.1	3%	0.033	38%	0.382	C	S	.	.	H	α-helix	trans	-60.7	-40.6	174.7	0	0	0	0	0	111.7	S164 F165 V168 K269 L270 I276 W277	S164-A273 WeakPolarHBondContact CB-O 3.38Å; F165-A273 HydrophobicContact CB-CB 4.3Å; F165-A273 HydrophobicContact CD2-CB 4.41Å; V168-A273 HydrophobicContact CG2-CB 4.06Å; K269-A273 WeakPolarHBondContact O-CB 3.2Å; K269-A273 PolarHBondContact O-N 2.97Å; L270-A273 PolarHBondContact O-N 3.3Å; A273-I276 PolarHBondContact O-N 2.7Å; A273-W277 VanDerWaalsContact O-CB 3.29Å; A273-W277 WeakPolarHBondContact O-CB 3.32Å; A273-W277 PolarHBondContact O-N 2.89Å
274	L	87.1	Confident	81.8	Confident	84 Å²	84	74.3 Å²	74.3	44%	0.44	40%	0.398	S	S	.	.	H	α-helix	trans	-64.7	-39.7	173.7	-74.8	168	0	0	0	112.2	L270 H271 R272 W277 S278	L270-L274 HydrophobicContact CG-CD1 4.33Å; L270-L274 WeakPolarHBondContact O-CB 3.26Å; L270-L274 WeakPolarHBondContact O-CG 3.21Å; L270-L274 PolarHBondContact O-N 3.17Å; H271-L274 PolarHBondContact O-N 3.3Å; R272-L274 VanDerWaalsContact C-N 3.31Å; R272-L274 PolarHBondContact O-N 3.5Å; L274-W277 HydrophobicContact CD2-CE3 3.86Å; L274-W277 HydrophobicContact CD2-CZ3 4.09Å; L274-W277 PolarHBondContact O-N 2.86Å; L274-S278 WeakPolarHBondContact O-CB 3.49Å; L274-S278 PolarHBondContact O-N 3.3Å; L274-S278 PolarHBondContact O-OG 3.42Å
275	A	85.8	Confident	81.9	Confident	45 Å²	45	74.1 Å²	74.1	37%	0.372	38%	0.382	S	S	.	.	H	α-helix	trans	-62.6	-47.7	175.3	0	0	0	0	0	111.4	H271 R272 W277 S278 G279	H271-A275 PolarHBondContact O-N 3.27Å; R272-A275 WeakPolarHBondContact O-CB 3.19Å; R272-A275 PolarHBondContact O-N 3.39Å; A275-W277 VanDerWaalsContact C-N 3.32Å; A275-W277 PolarHBondContact O-N 3.37Å; A275-S278 PolarHBondContact O-N 2.99Å; A275-S278 PolarHBondContact O-OG 3.04Å; A275-G279 PolarHBondContact O-N 3.47Å
276	I	84.9	Confident	80.9	Confident	7 Å²	7	71.2 Å²	71.2	4%	0.036	38%	0.38	C	S	.	.	H	α-helix	trans	-57.7	-46.4	175.2	-66.2	161.6	0	0	0	110.6	V168 R272 A273 S278 G279 F280 G281 V287 T289	V168-I276 HydrophobicContact CG2-CD1 3.49Å; V168-I276 VanDerWaalsContact CG2-CD1 3.49Å; R272-I276 HydrophobicContact CG-CD1 4.07Å; R272-I276 VanDerWaalsContact O-CG1 3.3Å; R272-I276 WeakPolarHBondContact O-CG1 3.46Å; R272-I276 PolarHBondContact O-N 2.66Å; A273-I276 PolarHBondContact O-N 2.7Å; I276-S278 PolarHBondContact O-N 2.86Å; I276-G279 PolarHBondContact O-N 3.33Å; I276-F280 PolarHBondContact O-N 2.93Å; I276-G281 PolarHBondContact O-N 2.84Å; I276-V287 HydrophobicContact CB-CG1 4.25Å; I276-V287 HydrophobicContact CG1-CG1 3.62Å; I276-V287 HydrophobicContact CG2-CG1 4.24Å; I276-T289 HydrophobicContact CD1-CG2 3.74Å; I276-T289 HydrophobicContact CG1-CG2 4.2Å
277	W	86.8	Confident	80.4	Confident	98 Å²	98	66.1 Å²	66.1	37%	0.371	36%	0.356	S	S	.	.	H	α-helix	trans	-62.2	-44.5	179.3	-176.5	9.9	0	0	0	111.7	V157 S164 A273 L274 A275 G279 F280	V157-W277 HydrophobicContact CG1-CH2 4.43Å; V157-W277 HydrophobicContact CG1-CZ2 3.7Å; S164-W277 WeakPolarHBondContact OG-CA 3.24Å; A273-W277 VanDerWaalsContact O-CB 3.29Å; A273-W277 WeakPolarHBondContact O-CB 3.32Å; A273-W277 PolarHBondContact O-N 2.89Å; L274-W277 HydrophobicContact CD2-CE3 3.86Å; L274-W277 HydrophobicContact CD2-CZ3 4.09Å; L274-W277 PolarHBondContact O-N 2.86Å; A275-W277 VanDerWaalsContact C-N 3.32Å; A275-W277 PolarHBondContact O-N 3.37Å; W277-G279 VanDerWaalsContact C-N 3.27Å; W277-G279 PolarHBondContact O-N 3.5Å; W277-F280 PolarHBondContact O-N 3.34Å; W277-F280 VanDerWaalsContact O-N 3.07Å
278	S	85	Confident	79.8	Confident	92 Å²	92	62.3 Å²	62.3	64%	0.643	35%	0.347	S	S	*	.	H	α-helix	trans	-64.4	-29.5	178.3	70.4	0	0	0	0	113.5	L274 A275 I276 F280	L274-S278 WeakPolarHBondContact O-CB 3.49Å; L274-S278 PolarHBondContact O-N 3.3Å; L274-S278 PolarHBondContact O-OG 3.42Å; A275-S278 PolarHBondContact O-N 2.99Å; A275-S278 PolarHBondContact O-OG 3.04Å; I276-S278 PolarHBondContact O-N 2.86Å; S278-F280 VanDerWaalsContact C-N 3.31Å
279	G	81.2	Confident	79.3	Confident	7 Å²	7	61.9 Å²	61.9	7%	0.072	34%	0.34	C	S	.	.	T	Hydrogen-bonded Turn	trans	-86.8	6.9	174.4	0	0	0	0	0	114.6	A275 I276 W277 G281 M282 T285	A275-G279 PolarHBondContact O-N 3.47Å; I276-G279 PolarHBondContact O-N 3.33Å; W277-G279 VanDerWaalsContact C-N 3.27Å; W277-G279 PolarHBondContact O-N 3.5Å; G279-G281 PolarHBondContact O-N 3.35Å; G279-M282 PolarHBondContact O-N 2.68Å; G279-M282 VanDerWaalsContact O-N 3.08Å; G279-T285 PolarHBondContact O-OG1 2.92Å
280	F	81.6	Confident	78.8	Confident	167 Å²	167	60.5 Å²	60.5	73%	0.732	34%	0.335	S	S	*	.	T	Hydrogen-bonded Turn	trans	52.3	23.2	-172	-61.7	-82.3	0	0	0	114.2	I276 W277 S278 M282	I276-F280 PolarHBondContact O-N 2.93Å; W277-F280 PolarHBondContact O-N 3.34Å; W277-F280 VanDerWaalsContact O-N 3.07Å; S278-F280 VanDerWaalsContact C-N 3.31Å; F280-M282 HydrophobicContact CB-CE 4.33Å; F280-M282 HydrophobicContact CB-CG 4.47Å; F280-M282 PolarHBondContact O-N 3.4Å
281	G	74	Confident	78.1	Confident	24 Å²	24	57 Å²	57	25%	0.247	32%	0.318	C	S	.	.	T	Hydrogen-bonded Turn	trans	66.2	18.4	-176.6	0	0	0	0	0	115.3	I276 G279	I276-G281 PolarHBondContact O-N 2.84Å; G279-G281 PolarHBondContact O-N 3.35Å
282	M	81.8	Confident	77.8	Confident	48 Å²	48	51.7 Å²	51.7	24%	0.236	29%	0.293	C	S	.	.			trans	-84.7	134.5	179.2	-62.7	-174.8	-65.7	0	0	111.7	V206 G279 F280 L284 T285	V206-M282 HydrophobicContact CG2-SD 4.21Å; G279-M282 PolarHBondContact O-N 2.68Å; G279-M282 VanDerWaalsContact O-N 3.08Å; F280-M282 HydrophobicContact CB-CE 4.33Å; F280-M282 HydrophobicContact CB-CG 4.47Å; F280-M282 PolarHBondContact O-N 3.4Å; M282-L284 VanDerWaalsContact C-N 3.27Å; M282-L284 PolarHBondContact O-N 3.35Å; M282-T285 HydrophobicContact CB-CG2 4.33Å; M282-T285 HydrophobicContact CE-CG2 4.04Å; M282-T285 PolarHBondContact O-N 3.08Å; M282-T285 VanDerWaalsContact O-N 3.07Å; M282-T285 PolarHBondContact O-OG1 2.97Å
283	S	75.7	Confident	77.8	Confident	20 Å²	20	49 Å²	49	14%	0.14	28%	0.284	C	S	.	.	G	3₁₀ helix	trans	-64.2	-29	172	68.9	0	0	0	0	113	F198 E202 T285 G286 V287	F198-S283 WeakPolarHBondContact CD1-OG 3.2Å; F198-S283 VanDerWaalsContact CE1-OG 3.24Å; F198-S283 WeakPolarHBondContact CE1-OG 3.28Å; E202-S283 WeakPolarHBondContact OE1-CA 3.47Å; E202-S283 VanDerWaalsContact OE1-CB 3.32Å; E202-S283 WeakPolarHBondContact OE1-CB 3.17Å; E202-S283 PolarHBondContact OE1-N 3.1Å; E202-S283 PolarHBondContact OE1-OG 3.07Å; E202-S283 PolarHBondContact OE2-OG 3.4Å; E202-S283 VanDerWaalsContact OE2-OG 3.04Å; S283-T285 PolarHBondContact O-N 3.04Å; S283-T285 VanDerWaalsContact O-N 3.1Å; S283-G286 WeakPolarHBondContact O-CA 3.23Å; S283-G286 PolarHBondContact O-N 3.33Å; S283-V287 WeakPolarHBondContact CA-O 3.27Å
284	L	69.9	Low	77.6	Confident	107 Å²	107	51.4 Å²	51.4	56%	0.56	29%	0.294	S	S	*	.	G	3₁₀ helix	trans	-54.4	-26	169.6	-84.4	155.5	0	0	0	113.2	E202 M282 G286	E202-L284 HydrophobicContact CB-CD1 3.5Å; E202-L284 HydrophobicContact CB-CG 4.44Å; E202-L284 HydrophobicContact CG-CD1 4.42Å; E202-L284 VanDerWaalsContact OE2-CB 3.27Å; E202-L284 WeakPolarHBondContact OE2-CB 3.44Å; E202-L284 WeakPolarHBondContact OE2-CD1 3.48Å; E202-L284 WeakPolarHBondContact OE2-CG 3.29Å; E202-L284 PolarHBondContact OE2-N 3.14Å; M282-L284 VanDerWaalsContact C-N 3.27Å; M282-L284 PolarHBondContact O-N 3.35Å; L284-G286 VanDerWaalsContact C-N 3.29Å
285	T	66	Low	77.2	Confident	71 Å²	71	47.8 Å²	47.8	44%	0.436	28%	0.275	S	S	.	.	G	3₁₀ helix	trans	-89.9	8.2	176.5	67.2	0	0	0	0	113.2	G279 M282 S283	G279-T285 PolarHBondContact O-OG1 2.92Å; M282-T285 HydrophobicContact CB-CG2 4.33Å; M282-T285 HydrophobicContact CE-CG2 4.04Å; M282-T285 PolarHBondContact O-N 3.08Å; M282-T285 VanDerWaalsContact O-N 3.07Å; M282-T285 PolarHBondContact O-OG1 2.97Å; S283-T285 PolarHBondContact O-N 3.04Å; S283-T285 VanDerWaalsContact O-N 3.1Å
286	G	62.9	Low	77.4	Confident	59 Å²	59	45.7 Å²	45.7	61%	0.608	26%	0.258	S	S	*	.	T	Hydrogen-bonded Turn	trans	82.6	11.2	-179.7	0	0	0	0	0	114	S283 L284	S283-G286 WeakPolarHBondContact O-CA 3.23Å; S283-G286 PolarHBondContact O-N 3.33Å; L284-G286 VanDerWaalsContact C-N 3.29Å
287	V	71.7	Confident	77.7	Confident	25 Å²	25	45.5 Å²	45.5	15%	0.152	26%	0.257	C	S	.	.			trans	-91.6	105.6	-179.4	177.8	0	0	0	0	109.7	I276 S283 T289	I276-V287 HydrophobicContact CB-CG1 4.25Å; I276-V287 HydrophobicContact CG1-CG1 3.62Å; I276-V287 HydrophobicContact CG2-CG1 4.24Å; S283-V287 WeakPolarHBondContact CA-O 3.27Å; V287-T289 HydrophobicContact CG1-CG2 4.1Å
288	H	70.8	Confident	78	Confident	117 Å²	117	42.6 Å²	42.6	54%	0.542	25%	0.248	S	C	.	.			trans	-105.4	115.6	168.2	-65.2	-78.4	0	0	0	109.5	R272	R272-H288 PolarHBondContact NH2-O 3.08Å
289	T	72.9	Confident	78.5	Confident	27 Å²	27	38.2 Å²	38.2	17%	0.166	22%	0.217	C	C	.	.			trans	-111.1	147.4	172.7	49.3	0	0	0	0	109.3	I276 V287	I276-T289 HydrophobicContact CD1-CG2 3.74Å; I276-T289 HydrophobicContact CG1-CG2 4.2Å; V287-T289 HydrophobicContact CG1-CG2 4.1Å
290	C	74.8	Confident	79.2	Confident	9 Å²	9	37.9 Å²	37.9	6%	0.061	21%	0.214	C	C	.	.			trans	-119.8	153.1	172.7	-50.4	0	0	0	0	109.3	H171 V174 C258 Y293	H171-C290 WeakPolarHBondContact CA-O 3.5Å; H171-C290 VanDerWaalsContact CB-O 3.31Å; H171-C290 WeakPolarHBondContact CB-O 3.25Å; H171-C290 WeakPolarHBondContact ND1-CA 3.44Å; H171-C290 VanDerWaalsContact ND1-CB 3.27Å; H171-C290 WeakPolarHBondContact ND1-CB 3.44Å; H171-C290 PolarHBondContact ND1-N 3.06Å; H171-C290 PolarHBondContact ND1-O 3.11Å; H171-C290 VanDerWaalsContact ND1-O 3.14Å; V174-C290 HydrophobicContact CG2-CB 4.31Å; C258-C290 HydrophobicContact CB-CB 3.66Å; C258-C290 WeakPolarHBondContact CB-SG 3.27Å; C258-C290 WeakPolarHBondContact SG-CB 3.12Å; C258-C290 CovalentContact SG-SG 2.01Å; C258-C290 PolarHBondContact SG-SG 3.5Å; C290-Y293 WeakPolarHBondContact CB-OH 3.33Å
291	G	71.4	Confident	79.9	Confident	2 Å²	2	32 Å²	32	2%	0.021	19%	0.192	C	C	.	.	S	Bend	trans	101.1	-2.9	174.7	0	0	0	0	0	114.3	V170 Y293	V170-G291 WeakPolarHBondContact CG1-O 3.37Å; G291-Y293 PolarHBondContact O-N 3.07Å
292	D	81.3	Confident	81	Confident	14 Å²	14	31 Å²	31	8%	0.075	18%	0.181	C	C	.	.			trans	-91.4	38.2	-179.6	76.5	-57.6	0	0	0	113.4	M167 R240 M244 H341	M167-D292 HydrophobicContact CE-CB 3.49Å; M167-D292 VanDerWaalsContact CE-CB 3.49Å; M167-D292 HydrophobicContact SD-CB 3.29Å; M167-D292 WeakPolarHBondContact SD-CB 3.18Å; R240-D292 IonicContact CZ-OD2 2.86Å; R240-D292 PolarHBondContact NH2-O 2.91Å; R240-D292 IonicContact NH2-OD2 3.19Å; R240-D292 PolarHBondContact NH2-OD2 3.29Å; M244-D292 HydrophobicContact CE-CB 3.64Å; M244-D292 VanDerWaalsContact CE-O 3.23Å; M244-D292 WeakPolarHBondContact CE-O 3.49Å; M244-D292 HydrophobicContact SD-CB 3.95Å; D292-H341 IonicContact OD2-CE1 3.28Å
293	Y	81.4	Confident	81.7	Confident	3 Å²	3	28.8 Å²	28.8	1%	0.012	17%	0.17	C	C	.	.			trans	-91.2	4.3	-171.8	-45.9	-57.5	0	0	0	114.5	V251 P252 C290 G291 E340 D345	V251-Y293 HydrophobicContact CB-CE2 4.2Å; V251-Y293 WeakPolarHBondContact CG1-OH 3.4Å; V251-Y293 HydrophobicContact CG2-CE2 3.94Å; P252-Y293 VanDerWaalsContact CD-CZ 3.46Å; P252-Y293 HydrophobicContact CG-CD1 3.97Å; P252-Y293 HydrophobicContact CG-CE1 3.89Å; C290-Y293 WeakPolarHBondContact CB-OH 3.33Å; G291-Y293 PolarHBondContact O-N 3.07Å; Y293-E340 WeakPolarHBondContact CD1-O 3.49Å; Y293-E340 WeakPolarHBondContact CE1-O 3.47Å; Y293-D345 WeakPolarHBondContact CA-OD2 3.18Å; Y293-D345 WeakPolarHBondContact O-CB 3.35Å; Y293-D345 VanDerWaalsContact O-OD2 3.12Å
294	M	81.6	Confident	82.7	Confident	53 Å²	53	27.8 Å²	27.8	26%	0.261	16%	0.163	S	C	.	.	S	Bend	trans	-114.1	107.8	172.5	-164.8	158.4	93.5	0	0	109.2	T243 M244 T247 L249	T243-M294 VanDerWaalsContact C-CE 3.41Å; T243-M294 VanDerWaalsContact CB-CE 3.48Å; T243-M294 HydrophobicContact CG2-CE 4.23Å; T243-M294 WeakPolarHBondContact O-CE 3.45Å; M244-M294 WeakPolarHBondContact CE-O 3.45Å; M244-M294 VanDerWaalsContact CG-O 3.3Å; M244-M294 WeakPolarHBondContact CG-O 3.49Å; T247-M294 HydrophobicContact CG2-SD 4.39Å; L249-M294 HydrophobicContact CD1-CB 4.18Å
295	F	79.2	Confident	84	Confident	9 Å²	9	23.3 Å²	23.3	4%	0.039	14%	0.14	C	C	.	.	S	Bend	trans	72.8	104.9	-171	-161.2	-105.2	0	0	0	115.1	V236 R240 M244 G297 V300 D345 I348 A349 I352	V236-F295 HydrophobicContact CG1-CE1 3.37Å; V236-F295 HydrophobicContact CG1-CZ 3.5Å; R240-F295 HydrophobicContact CB-CD1 3.66Å; R240-F295 HydrophobicContact CB-CE1 4.26Å; R240-F295 HydrophobicContact CG-CB 4.26Å; R240-F295 HydrophobicContact CG-CD1 3.74Å; R240-F295 HydrophobicContact CG-CG 4.5Å; R240-F295 PolarHBondContact NE-O 3.27Å; R240-F295 PolarHBondContact NH2-O 3.07Å; M244-F295 VanDerWaalsContact CE-O 3.31Å; M244-F295 WeakPolarHBondContact CE-O 3.46Å; F295-G297 PolarHBondContact O-N 3.34Å; F295-V300 HydrophobicContact CD1-CG2 4.04Å; F295-V300 HydrophobicContact CE1-CG2 3.28Å; F295-V300 HydrophobicContact CE2-CG2 4.33Å; F295-V300 HydrophobicContact CZ-CG2 3.44Å; F295-V300 VanDerWaalsContact CZ-CG2 3.44Å; F295-D345 WeakPolarHBondContact CA-OD1 3.48Å; F295-D345 PolarHBondContact N-OD1 3.34Å; F295-I348 HydrophobicContact CD2-CG2 4.02Å; F295-I348 HydrophobicContact CE2-CG2 4.42Å; F295-A349 HydrophobicContact CD2-CB 4.24Å; F295-A349 HydrophobicContact CE2-CB 4.19Å; F295-I352 HydrophobicContact CD2-CD1 4.08Å; F295-I352 HydrophobicContact CE2-CB 3.67Å; F295-I352 HydrophobicContact CE2-CD1 3.64Å; F295-I352 HydrophobicContact CE2-CG1 4.07Å; F295-I352 HydrophobicContact CE2-CG2 3.95Å; F295-I352 HydrophobicContact CZ-CB 4.05Å; F295-I352 HydrophobicContact CZ-CD1 4.49Å; F295-I352 HydrophobicContact CZ-CG2 3.89Å
296	S	89.9	Confident	85.5	Confident	0 Å²	0	20 Å²	20	0%	0	12%	0.119	C	C	.	.			trans	-80.9	116.5	-171.8	174.5	0	0	0	0	111.9	T299 V300 D345	S296-T299 PolarHBondContact O-N 2.99Å; S296-T299 PolarHBondContact OG-OG1 3.4Å; S296-T299 VanDerWaalsContact OG-OG1 3.13Å; S296-V300 VanDerWaalsContact O-CG2 3.28Å; S296-V300 WeakPolarHBondContact O-CG2 3.39Å; S296-V300 PolarHBondContact O-N 3.21Å; S296-V300 VanDerWaalsContact O-N 3.09Å; S296-D345 PolarHBondContact N-OD1 3.27Å
297	G	91.4	Very high	87.1	Confident	3 Å²	3	17.9 Å²	17.9	3%	0.031	9%	0.093	C	C	.	.	H	α-helix	trans	-70.3	-36.2	-177.6	0	0	0	0	0	113.8	R240 F295 T299 V300 V301	R240-G297 VanDerWaalsContact CZ-CA 3.41Å; R240-G297 VanDerWaalsContact NH2-N 3.11Å; F295-G297 PolarHBondContact O-N 3.34Å; G297-T299 VanDerWaalsContact C-N 3.32Å; G297-T299 PolarHBondContact O-N 3.33Å; G297-V300 WeakPolarHBondContact O-CB 3.31Å; G297-V300 PolarHBondContact O-N 3.03Å; G297-V301 VanDerWaalsContact O-CG2 3.23Å; G297-V301 WeakPolarHBondContact O-CG2 3.1Å; G297-V301 PolarHBondContact O-N 3.38Å
298	H	93	Very high	88.3	Confident	37 Å²	37	16.7 Å²	16.7	17%	0.171	9%	0.086	C	C	.	.	H	α-helix	trans	-60.9	-45.4	175.1	-68.8	99.2	0	0	0	110.6	F198 E202 V300 V301 I302 I335	F198-H298 AromaticContact CZ-CE1 3.58Å; F198-H298 AromaticContact CZ-ND1 3.69Å; E202-H298 IonicContact OE1-NE2 3.91Å; H298-V300 VanDerWaalsContact C-N 3.35Å; H298-V300 PolarHBondContact O-N 2.86Å; H298-V301 PolarHBondContact O-N 3.42Å; H298-I302 WeakPolarHBondContact O-CB 3.42Å; H298-I302 VanDerWaalsContact O-CG1 3.23Å; H298-I302 WeakPolarHBondContact O-CG1 3.42Å; H298-I302 PolarHBondContact O-N 3.45Å; H298-I335 HydrophobicContact CB-CD1 3.64Å; H298-I335 HydrophobicContact CB-CG1 4.33Å
299	T	95.6	Very high	89.4	Confident	0 Å²	0	11.1 Å²	11.1	0%	0	6%	0.06	C	C	.	.	H	α-helix	trans	-60.1	-44.8	175.6	-57.1	0	0	0	0	111.5	S296 G297 T303 I332 I335 V346 A349 F350	S296-T299 PolarHBondContact O-N 2.99Å; S296-T299 PolarHBondContact OG-OG1 3.4Å; S296-T299 VanDerWaalsContact OG-OG1 3.13Å; G297-T299 VanDerWaalsContact C-N 3.32Å; G297-T299 PolarHBondContact O-N 3.33Å; T299-T303 WeakPolarHBondContact O-CB 3.45Å; T299-T303 PolarHBondContact O-N 2.98Å; T299-T303 PolarHBondContact O-OG1 2.65Å; T299-I332 HydrophobicContact CG2-CD1 4.44Å; T299-I332 HydrophobicContact CG2-CG1 4.18Å; T299-I335 WeakPolarHBondContact OG1-CD1 3.39Å; T299-V346 HydrophobicContact CG2-CG1 4.07Å; T299-A349 HydrophobicContact CG2-CB 3.71Å; T299-F350 HydrophobicContact CG2-CB 4.31Å
300	V	95.9	Very high	90.4	Very high	0 Å²	0	11.4 Å²	11.4	0%	0	6%	0.062	C	C	.	.	H	α-helix	trans	-58.4	-50.8	176	170.1	0	0	0	0	111.3	V236 F237 F295 S296 G297 H298 T303 M304 A349	V236-V300 HydrophobicContact CB-CG1 4.28Å; V236-V300 HydrophobicContact CG1-CB 4.35Å; V236-V300 HydrophobicContact CG1-CG1 3.44Å; V236-V300 VanDerWaalsContact CG1-CG1 3.44Å; V236-V300 HydrophobicContact CG1-CG2 3.89Å; F237-V300 HydrophobicContact CD2-CG1 4.31Å; F237-V300 HydrophobicContact CE2-CB 4.38Å; F237-V300 HydrophobicContact CE2-CG1 3.78Å; F295-V300 HydrophobicContact CD1-CG2 4.04Å; F295-V300 HydrophobicContact CE1-CG2 3.28Å; F295-V300 HydrophobicContact CE2-CG2 4.33Å; F295-V300 HydrophobicContact CZ-CG2 3.44Å; F295-V300 VanDerWaalsContact CZ-CG2 3.44Å; S296-V300 VanDerWaalsContact O-CG2 3.28Å; S296-V300 WeakPolarHBondContact O-CG2 3.39Å; S296-V300 PolarHBondContact O-N 3.21Å; S296-V300 VanDerWaalsContact O-N 3.09Å; G297-V300 WeakPolarHBondContact O-CB 3.31Å; G297-V300 PolarHBondContact O-N 3.03Å; H298-V300 VanDerWaalsContact C-N 3.35Å; H298-V300 PolarHBondContact O-N 2.86Å; V300-T303 PolarHBondContact O-N 2.95Å; V300-M304 WeakPolarHBondContact O-CB 3.23Å; V300-M304 PolarHBondContact O-N 2.93Å; V300-A349 HydrophobicContact CG2-CB 4.13Å
301	V	95.9	Very high	91.3	Very high	45 Å²	45	14.4 Å²	14.4	27%	0.273	8%	0.075	S	C	.	.	H	α-helix	trans	-62.2	-51.1	-176.9	172	0	0	0	0	110.4	M233 F237 G297 H298 T303 M304 L305	M233-V301 HydrophobicContact CE-CB 4.42Å; M233-V301 HydrophobicContact CE-CG2 3.65Å; F237-V301 HydrophobicContact CE2-CG2 4.03Å; F237-V301 HydrophobicContact CZ-CG2 3.78Å; G297-V301 VanDerWaalsContact O-CG2 3.23Å; G297-V301 WeakPolarHBondContact O-CG2 3.1Å; G297-V301 PolarHBondContact O-N 3.38Å; H298-V301 PolarHBondContact O-N 3.42Å; V301-T303 PolarHBondContact O-N 3.49Å; V301-M304 PolarHBondContact O-N 3.12Å; V301-L305 HydrophobicContact CG1-CD1 3.69Å; V301-L305 HydrophobicContact CG1-CG 4.37Å; V301-L305 WeakPolarHBondContact O-CB 3.47Å; V301-L305 WeakPolarHBondContact O-CG 3.21Å; V301-L305 PolarHBondContact O-N 3.36Å
302	I	96.8	Very high	92.2	Very high	3 Å²	3	14.5 Å²	14.5	2%	0.015	8%	0.075	C	C	.	.	H	α-helix	trans	-59.9	-48.2	-179.4	-67.6	173.2	0	0	0	110.3	L208 H298 L305 N306 N328 I335	L208-I302 HydrophobicContact CD1-CB 4.42Å; L208-I302 HydrophobicContact CD1-CG2 3.66Å; H298-I302 WeakPolarHBondContact O-CB 3.42Å; H298-I302 VanDerWaalsContact O-CG1 3.23Å; H298-I302 WeakPolarHBondContact O-CG1 3.42Å; H298-I302 PolarHBondContact O-N 3.45Å; I302-L305 PolarHBondContact O-N 3.2Å; I302-N306 WeakPolarHBondContact O-CB 3.44Å; I302-N306 PolarHBondContact O-N 3.43Å; I302-N328 HydrophobicContact CG2-CB 4.28Å; I302-N328 WeakPolarHBondContact CG2-OD1 3.48Å; I302-I335 HydrophobicContact CD1-CD1 4.13Å
303	T	97.3	Very high	92.7	Very high	0 Å²	0	13.9 Å²	13.9	0%	0	7%	0.072	C	C	.	.	H	α-helix	trans	-65.9	-43.9	-178.9	-56.2	0	0	0	0	111.7	T299 V300 V301 N306 F307 N328 F350 T353	T299-T303 WeakPolarHBondContact O-CB 3.45Å; T299-T303 PolarHBondContact O-N 2.98Å; T299-T303 PolarHBondContact O-OG1 2.65Å; V300-T303 PolarHBondContact O-N 2.95Å; V301-T303 PolarHBondContact O-N 3.49Å; T303-N306 PolarHBondContact O-N 3.29Å; T303-F307 HydrophobicContact CG2-CD2 4Å; T303-F307 HydrophobicContact CG2-CE1 4.35Å; T303-F307 HydrophobicContact CG2-CE2 3.37Å; T303-F307 HydrophobicContact CG2-CZ 3.59Å; T303-F307 WeakPolarHBondContact O-CG 3.32Å; T303-F307 PolarHBondContact O-N 2.93Å; T303-N328 VanDerWaalsContact CA-OD1 3.23Å; T303-N328 WeakPolarHBondContact CA-OD1 3.29Å; T303-N328 PolarHBondContact N-OD1 3.01Å; T303-N328 PolarHBondContact OG1-OD1 3.5Å; T303-F350 HydrophobicContact CG2-CD2 3.72Å; T303-F350 HydrophobicContact CG2-CE2 3.91Å; T303-T353 HydrophobicContact CG2-CG2 3.84Å
304	M	96.9	Very high	93	Very high	0 Å²	0	15.4 Å²	15.4	0%	0	8%	0.082	C	C	.	.	H	α-helix	trans	-63.6	-46.5	178.8	-168.8	72.4	78.4	0	0	110.8	L229 L232 M233 V236 V300 V301 N306 F307 F308 T353 F357	L229-M304 HydrophobicContact CD1-CG 4.36Å; L232-M304 HydrophobicContact CB-CE 3.91Å; L232-M304 HydrophobicContact CB-SD 4.2Å; L232-M304 HydrophobicContact CD1-SD 4.32Å; M233-M304 HydrophobicContact CG-CG 4.33Å; M233-M304 HydrophobicContact SD-CB 3.83Å; M233-M304 HydrophobicContact SD-CE 4.34Å; M233-M304 HydrophobicContact SD-CG 3.63Å; V236-M304 HydrophobicContact CG2-CE 3.9Å; V300-M304 WeakPolarHBondContact O-CB 3.23Å; V300-M304 PolarHBondContact O-N 2.93Å; V301-M304 PolarHBondContact O-N 3.12Å; M304-N306 VanDerWaalsContact C-N 3.35Å; M304-N306 PolarHBondContact O-N 3.35Å; M304-F307 PolarHBondContact O-N 3.42Å; M304-F308 HydrophobicContact CG-CD2 3.8Å; M304-F308 HydrophobicContact CG-CE2 3.87Å; M304-F308 WeakPolarHBondContact O-CD2 3.21Å; M304-F308 PolarHBondContact O-N 2.93Å; M304-F308 HydrophobicContact SD-CD2 4.01Å; M304-F308 HydrophobicContact SD-CE2 3.7Å; M304-T353 HydrophobicContact CB-CG2 4.09Å; M304-T353 HydrophobicContact CE-CG2 3.88Å; M304-T353 HydrophobicContact SD-CG2 4.22Å; M304-F357 HydrophobicContact SD-CD2 3.97Å
305	L	97.3	Very high	93.2	Very high	13 Å²	13	23.8 Å²	23.8	7%	0.068	11%	0.11	C	C	.	.	H	α-helix	trans	-60	-44.5	177	-72.7	169.7	0	0	0	111.4	L208 C209 W212 V301 I302 F307 F308 V309	L208-L305 HydrophobicContact CB-CB 4.11Å; L208-L305 HydrophobicContact CB-CD1 4.21Å; C209-L305 HydrophobicContact CB-CD1 3.92Å; W212-L305 HydrophobicContact CB-CD2 3.85Å; W212-L305 HydrophobicContact CG-CD2 3.84Å; V301-L305 HydrophobicContact CG1-CD1 3.69Å; V301-L305 HydrophobicContact CG1-CG 4.37Å; V301-L305 WeakPolarHBondContact O-CB 3.47Å; V301-L305 WeakPolarHBondContact O-CG 3.21Å; V301-L305 PolarHBondContact O-N 3.36Å; I302-L305 PolarHBondContact O-N 3.2Å; L305-F307 PolarHBondContact O-N 3.04Å; L305-F308 PolarHBondContact O-N 3.01Å; L305-V309 WeakPolarHBondContact O-CB 3.46Å; L305-V309 VanDerWaalsContact O-CG2 3.28Å; L305-V309 WeakPolarHBondContact O-CG2 3.24Å; L305-V309 PolarHBondContact O-N 3.2Å
306	N	97.5	Very high	93.5	Very high	0 Å²	0	26.5 Å²	26.5	0%	0	14%	0.141	C	C	.	.	H	α-helix	trans	-56	-50.2	174.8	174.1	49	0	0	0	111.6	I302 T303 M304 F308 V309 T310 S324 W325 N328	I302-N306 WeakPolarHBondContact O-CB 3.44Å; I302-N306 PolarHBondContact O-N 3.43Å; T303-N306 PolarHBondContact O-N 3.29Å; M304-N306 VanDerWaalsContact C-N 3.35Å; M304-N306 PolarHBondContact O-N 3.35Å; N306-F308 PolarHBondContact O-N 2.94Å; N306-V309 PolarHBondContact O-N 3.5Å; N306-T310 WeakPolarHBondContact O-CG2 3.33Å; N306-T310 PolarHBondContact O-N 3.43Å; N306-T310 PolarHBondContact O-OG1 3.21Å; N306-S324 WeakPolarHBondContact OD1-CB 3.29Å; N306-S324 PolarHBondContact OD1-O 3.49Å; N306-S324 PolarHBondContact OD1-OG 3.5Å; N306-W325 PolarHBondContact OD1-N 3.26Å; N306-N328 HydrophobicContact CB-CB 3.94Å
307	F	96.7	Very high	93.5	Very high	15 Å²	15	31.5 Å²	31.5	7%	0.066	16%	0.159	C	C	.	.	H	α-helix	trans	-62.6	-43.4	179.8	-66.5	-24.4	0	0	0	113.2	T303 M304 L305 V309 T310 E311 W325 F350 T354 F357	T303-F307 HydrophobicContact CG2-CD2 4Å; T303-F307 HydrophobicContact CG2-CE1 4.35Å; T303-F307 HydrophobicContact CG2-CE2 3.37Å; T303-F307 HydrophobicContact CG2-CZ 3.59Å; T303-F307 WeakPolarHBondContact O-CG 3.32Å; T303-F307 PolarHBondContact O-N 2.93Å; M304-F307 PolarHBondContact O-N 3.42Å; L305-F307 PolarHBondContact O-N 3.04Å; F307-V309 PolarHBondContact O-N 3.5Å; F307-T310 WeakPolarHBondContact CA-OG1 3.43Å; F307-T310 PolarHBondContact O-N 3.26Å; F307-T310 PolarHBondContact O-OG1 3.43Å; F307-E311 WeakPolarHBondContact O-CB 3.34Å; F307-E311 PolarHBondContact O-N 3.05Å; F307-W325 HydrophobicContact CD1-CH2 4.45Å; F307-W325 HydrophobicContact CD1-CZ2 4.38Å; F307-W325 AromaticContact CE1-CH2 3.61Å; F307-W325 HydrophobicContact CE1-CH2 3.61Å; F307-W325 AromaticContact CE1-CZ2 3.96Å; F307-W325 HydrophobicContact CE1-CZ2 3.96Å; F307-W325 HydrophobicContact CE1-CZ3 4.37Å; F307-F350 HydrophobicContact CZ-CE2 4.38Å; F307-T354 HydrophobicContact CE2-CG2 4.17Å; F307-T354 WeakPolarHBondContact CE2-OG1 3.29Å; F307-T354 HydrophobicContact CZ-CG2 4.07Å; F307-T354 WeakPolarHBondContact CZ-OG1 3.32Å; F307-F357 HydrophobicContact CB-CD1 4.05Å; F307-F357 HydrophobicContact CB-CD2 3.75Å; F307-F357 HydrophobicContact CB-CE1 3.93Å; F307-F357 HydrophobicContact CB-CE2 3.59Å; F307-F357 HydrophobicContact CB-CG 3.98Å; F307-F357 HydrophobicContact CB-CZ 3.7Å; F307-F357 HydrophobicContact CD2-CB 4.02Å; F307-F357 HydrophobicContact CD2-CD1 4.22Å; F307-F357 HydrophobicContact CD2-CD2 4.3Å; F307-F357 AromaticContact CD2-CG 3.92Å; F307-F357 HydrophobicContact CD2-CG 3.92Å; F307-F357 HydrophobicContact CG-CD1 4.32Å; F307-F357 HydrophobicContact CG-CD2 4.5Å; F307-F357 HydrophobicContact CG-CG 4.3Å
308	F	95.8	Very high	93.5	Very high	0 Å²	0	36.3 Å²	36.3	0%	0	18%	0.184	C	C	.	.	H	α-helix	trans	-62.1	-42.4	175.6	-93.3	-89.2	0	0	0	112.2	W212 R228 L229 L232 M304 L305 N306 T310 Y312 F357	W212-F308 HydrophobicContact CD2-CB 4.19Å; W212-F308 HydrophobicContact CE3-CB 3.81Å; W212-F308 HydrophobicContact CH2-CB 3.95Å; W212-F308 AromaticContact CH2-CD1 3.44Å; W212-F308 HydrophobicContact CH2-CD1 3.44Å; W212-F308 VanDerWaalsContact CH2-CD1 3.44Å; W212-F308 HydrophobicContact CH2-CE1 4.37Å; W212-F308 HydrophobicContact CH2-CG 4.13Å; W212-F308 HydrophobicContact CZ2-CB 4.3Å; W212-F308 AromaticContact CZ2-CD1 3.7Å; W212-F308 HydrophobicContact CZ2-CD1 3.7Å; W212-F308 HydrophobicContact CZ2-CE1 4.43Å; W212-F308 HydrophobicContact CZ2-CG 4.3Å; W212-F308 HydrophobicContact CZ3-CB 3.7Å; W212-F308 HydrophobicContact CZ3-CD1 4.05Å; W212-F308 HydrophobicContact CZ3-CG 4.37Å; W212-F308 WeakPolarHBondContact CZ3-O 3.27Å; R228-F308 HydrophobicContact CB-CE1 4.07Å; R228-F308 HydrophobicContact CB-CZ 4.16Å; L229-F308 HydrophobicContact CB-CD1 4.43Å; L229-F308 HydrophobicContact CB-CE1 3.9Å; L229-F308 HydrophobicContact CB-CE2 4.4Å; L229-F308 HydrophobicContact CB-CZ 3.89Å; L229-F308 HydrophobicContact CD1-CD1 4.22Å; L229-F308 HydrophobicContact CD1-CD2 3.63Å; L229-F308 HydrophobicContact CD1-CE1 4.28Å; L229-F308 HydrophobicContact CD1-CE2 3.7Å; L229-F308 HydrophobicContact CD1-CG 3.89Å; L229-F308 HydrophobicContact CD1-CZ 4.04Å; L232-F308 HydrophobicContact CD1-CE2 3.79Å; L232-F308 HydrophobicContact CD1-CZ 3.8Å; M304-F308 HydrophobicContact CG-CD2 3.8Å; M304-F308 HydrophobicContact CG-CE2 3.87Å; M304-F308 WeakPolarHBondContact O-CD2 3.21Å; M304-F308 PolarHBondContact O-N 2.93Å; M304-F308 HydrophobicContact SD-CD2 4.01Å; M304-F308 HydrophobicContact SD-CE2 3.7Å; L305-F308 PolarHBondContact O-N 3.01Å; N306-F308 PolarHBondContact O-N 2.94Å; F308-T310 VanDerWaalsContact C-N 3.35Å; F308-T310 PolarHBondContact O-N 3.42Å; F308-Y312 AromaticContact CD1-CD2 3.61Å; F308-Y312 HydrophobicContact CD1-CD2 3.61Å; F308-Y312 AromaticContact CD1-CE2 3.36Å; F308-Y312 HydrophobicContact CD1-CE2 3.36Å; F308-Y312 HydrophobicContact CE1-CD2 4.26Å; F308-Y312 AromaticContact CE1-CE2 3.56Å; F308-Y312 HydrophobicContact CE1-CE2 3.56Å; F308-Y312 HydrophobicContact CG-CD2 4.43Å; F308-Y312 HydrophobicContact CG-CE2 4.32Å; F308-Y312 WeakPolarHBondContact O-CD2 3.28Å; F308-Y312 PolarHBondContact O-N 3.36Å; F308-Y312 VanDerWaalsContact O-N 3.14Å; F308-F357 HydrophobicContact CD2-CD2 4.18Å; F308-F357 AromaticContact CD2-CE2 3.71Å; F308-F357 HydrophobicContact CD2-CE2 3.71Å; F308-F357 HydrophobicContact CE2-CD2 4.08Å; F308-F357 AromaticContact CE2-CE2 3.85Å; F308-F357 HydrophobicContact CE2-CE2 3.85Å; F308-F357 HydrophobicContact CG-CE2 4.23Å; F308-F357 HydrophobicContact CZ-CE2 4.46Å
309	V	95.3	Very high	93.6	Very high	0 Å²	0	41.9 Å²	41.9	0%	0	21%	0.209	C	C	.	.	H	α-helix	trans	-58.7	-48.4	173.7	169.5	0	0	0	0	110	I211 W212 L305 N306 F307 T313 I320	I211-V309 HydrophobicContact CG2-CG1 4.02Å; I211-V309 HydrophobicContact CG2-CG2 3.99Å; W212-V309 HydrophobicContact CB-CG2 3.95Å; W212-V309 HydrophobicContact CE3-CG2 4.21Å; L305-V309 WeakPolarHBondContact O-CB 3.46Å; L305-V309 VanDerWaalsContact O-CG2 3.28Å; L305-V309 WeakPolarHBondContact O-CG2 3.24Å; L305-V309 PolarHBondContact O-N 3.2Å; N306-V309 PolarHBondContact O-N 3.5Å; F307-V309 PolarHBondContact O-N 3.5Å; V309-T313 HydrophobicContact CG1-CG2 4.46Å; V309-T313 VanDerWaalsContact O-CB 3.32Å; V309-T313 WeakPolarHBondContact O-CB 3.5Å; V309-T313 WeakPolarHBondContact O-CG2 3.45Å; V309-T313 PolarHBondContact O-N 3.33Å; V309-T313 PolarHBondContact O-OG1 2.96Å; V309-I320 HydrophobicContact CG1-CG2 3.6Å
310	T	94.3	Very high	93.6	Very high	33 Å²	33	44 Å²	44	20%	0.202	22%	0.219	C	C	.	.	H	α-helix	trans	-68.6	-36.3	-177.4	54.6	0	0	0	0	114.5	N306 F307 F308 H321 S324	N306-T310 WeakPolarHBondContact O-CG2 3.33Å; N306-T310 PolarHBondContact O-N 3.43Å; N306-T310 PolarHBondContact O-OG1 3.21Å; F307-T310 WeakPolarHBondContact CA-OG1 3.43Å; F307-T310 PolarHBondContact O-N 3.26Å; F307-T310 PolarHBondContact O-OG1 3.43Å; F308-T310 VanDerWaalsContact C-N 3.35Å; F308-T310 PolarHBondContact O-N 3.42Å; T310-H321 HydrophobicContact CG2-CB 4.4Å; T310-S324 WeakPolarHBondContact CG2-OG 3.48Å
311	E	92.8	Very high	93.5	Very high	73 Å²	73	45.5 Å²	45.5	34%	0.341	23%	0.226	S	C	.	.	H	α-helix	trans	-73.1	-45	-177.7	179.3	69.5	-175.4	0	0	111.8	F307 F357 H361 N395	F307-E311 WeakPolarHBondContact O-CB 3.34Å; F307-E311 PolarHBondContact O-N 3.05Å; E311-F357 HydrophobicContact CB-CE1 4.48Å; E311-F357 HydrophobicContact CB-CZ 3.83Å; E311-F357 HydrophobicContact CG-CZ 4.16Å; E311-H361 IonicContact OE1-CD2 2.73Å; E311-N395 PolarHBondContact O-ND2 3.3Å
312	Y	91.2	Very high	93.5	Very high	3 Å²	3	47.4 Å²	47.4	1%	0.012	24%	0.238	C	C	.	.	H	α-helix	trans	-93.7	5.7	-172.1	-65.5	-74	0	0	0	114	W212 L225 R228 F308 H361 V393 Y397	W212-Y312 AromaticContact CH2-CD2 3.91Å; W212-Y312 HydrophobicContact CH2-CD2 3.91Å; W212-Y312 HydrophobicContact CH2-CG 4.41Å; W212-Y312 HydrophobicContact CZ3-CD2 4.04Å; W212-Y312 HydrophobicContact CZ3-CG 4.45Å; L225-Y312 HydrophobicContact CD1-CD1 3.64Å; L225-Y312 HydrophobicContact CD1-CE1 3.7Å; L225-Y312 HydrophobicContact CD1-CG 4.37Å; L225-Y312 HydrophobicContact CD2-CD1 3.83Å; L225-Y312 HydrophobicContact CD2-CD2 4.44Å; L225-Y312 HydrophobicContact CD2-CG 3.76Å; L225-Y312 HydrophobicContact CG-CD1 3.56Å; L225-Y312 HydrophobicContact CG-CD2 4.21Å; L225-Y312 HydrophobicContact CG-CE1 3.79Å; L225-Y312 HydrophobicContact CG-CE2 4.46Å; L225-Y312 HydrophobicContact CG-CG 3.78Å; R228-Y312 WeakPolarHBondContact CD-OH 3.39Å; R228-Y312 PolarHBondContact NH1-OH 3.48Å; F308-Y312 AromaticContact CD1-CD2 3.61Å; F308-Y312 HydrophobicContact CD1-CD2 3.61Å; F308-Y312 AromaticContact CD1-CE2 3.36Å; F308-Y312 HydrophobicContact CD1-CE2 3.36Å; F308-Y312 HydrophobicContact CE1-CD2 4.26Å; F308-Y312 AromaticContact CE1-CE2 3.56Å; F308-Y312 HydrophobicContact CE1-CE2 3.56Å; F308-Y312 HydrophobicContact CG-CD2 4.43Å; F308-Y312 HydrophobicContact CG-CE2 4.32Å; F308-Y312 WeakPolarHBondContact O-CD2 3.28Å; F308-Y312 PolarHBondContact O-N 3.36Å; F308-Y312 VanDerWaalsContact O-N 3.14Å; Y312-H361 AromaticContact CE2-NE2 3.78Å; Y312-H361 AromaticContact CZ-NE2 3.68Å; Y312-H361 PolarHBondContact OH-NE2 3.44Å; Y312-V393 HydrophobicContact CE1-CB 4.41Å; Y312-Y397 PolarHBondContact O-OH 3.21Å
313	T	90.6	Very high	93.5	Very high	2 Å²	2	50 Å²	50	1%	0.012	25%	0.251	C	S	.	.	S	Bend	trans	-104.2	151.9	172.9	54.6	0	0	0	0	113.2	V215 V309 W317 H321 N395 Y397	V215-T313 HydrophobicContact CB-CG2 4.47Å; V215-T313 HydrophobicContact CG1-CG2 4.03Å; V215-T313 HydrophobicContact CG2-CG2 3.53Å; V309-T313 HydrophobicContact CG1-CG2 4.46Å; V309-T313 VanDerWaalsContact O-CB 3.32Å; V309-T313 WeakPolarHBondContact O-CB 3.5Å; V309-T313 WeakPolarHBondContact O-CG2 3.45Å; V309-T313 PolarHBondContact O-N 3.33Å; V309-T313 PolarHBondContact O-OG1 2.96Å; T313-W317 HydrophobicContact CG2-CE3 4.24Å; T313-H321 PolarHBondContact OG1-CD2 3.14Å; T313-H321 VanDerWaalsContact OG1-CD2 3.23Å; T313-H321 PolarHBondContact OG1-NE2 3.37Å; T313-N395 PolarHBondContact O-ND2 2.99Å; T313-Y397 VanDerWaalsContact CA-OH 3.25Å; T313-Y397 WeakPolarHBondContact CA-OH 3.46Å; T313-Y397 WeakPolarHBondContact CG2-OH 3.48Å
314	P	88.6	Confident	93.4	Very high	34 Å²	34	50 Å²	50	22%	0.221	25%	0.251	C	S	.	.			trans	-64.6	145.3	-178.3	-18.9	33.5	0	0	0	111.2	G316 W317 Y397	P314-G316 PolarHBondContact O-N 3.42Å; P314-W317 HydrophobicContact CG-CD2 4.18Å; P314-W317 HydrophobicContact CG-CG 4.45Å; P314-W317 PolarHBondContact O-N 3.13Å; P314-Y397 HydrophobicContact CG-CD2 4.13Å; P314-Y397 HydrophobicContact CG-CE2 3.56Å
315	R	85.1	Confident	93.4	Very high	230 Å²	230	55.6 Å²	55.6	87%	0.868	27%	0.273	S	S	*	.	T	Hydrogen-bonded Turn	trans	-59.2	-17.5	178.3	-65.8	-176.1	-178.9	149	0.4	114.7	W317 N318	R315-W317 VanDerWaalsContact C-N 3.34Å; R315-N318 PolarHBondContact O-OD1 3.13Å
316	G	85.7	Confident	93.5	Very high	65 Å²	65	58 Å²	58	67%	0.67	29%	0.288	S	S	*	.	T	Hydrogen-bonded Turn	trans	-79.7	-12.6	176.6	0	0	0	0	0	114.1	P314 N318	P314-G316 PolarHBondContact O-N 3.42Å; G316-N318 PolarHBondContact O-N 3.28Å
317	W	89.7	Confident	93.4	Very high	105 Å²	105	58.9 Å²	58.9	40%	0.398	29%	0.292	S	S	.	.			trans	-88.5	52.5	-176.4	-68.8	8.8	0	0	0	111.8	T313 P314 R315 F319 I320 H321 Y397	T313-W317 HydrophobicContact CG2-CE3 4.24Å; P314-W317 HydrophobicContact CG-CD2 4.18Å; P314-W317 HydrophobicContact CG-CG 4.45Å; P314-W317 PolarHBondContact O-N 3.13Å; R315-W317 VanDerWaalsContact C-N 3.34Å; W317-F319 PolarHBondContact O-N 2.99Å; W317-F319 VanDerWaalsContact O-N 3.1Å; W317-I320 HydrophobicContact CB-CB 4.46Å; W317-I320 HydrophobicContact CB-CD1 4.34Å; W317-I320 HydrophobicContact CD2-CD1 4.05Å; W317-I320 HydrophobicContact CE3-CD1 3.37Å; W317-I320 HydrophobicContact CG-CD1 4.5Å; W317-I320 HydrophobicContact CZ3-CD1 3.93Å; W317-I320 PolarHBondContact O-N 2.86Å; W317-H321 PolarHBondContact O-N 3.26Å; W317-Y397 HydrophobicContact CH2-CE1 4.32Å; W317-Y397 HydrophobicContact CZ3-CE1 4.35Å
318	N	92.6	Very high	93.5	Very high	104 Å²	104	58.4 Å²	58.4	56%	0.556	29%	0.29	S	S	*	.	H	α-helix	trans	-55.1	-33.7	-175.4	-66	-18.3	0	0	0	113	R315 G316 H321 T322	R315-N318 PolarHBondContact O-OD1 3.13Å; G316-N318 PolarHBondContact O-N 3.28Å; N318-H321 PolarHBondContact O-N 3.49Å; N318-T322 VanDerWaalsContact O-CB 3.29Å; N318-T322 WeakPolarHBondContact O-CB 3.31Å; N318-T322 PolarHBondContact O-N 2.7Å; N318-T322 PolarHBondContact O-OG1 3.37Å
319	F	94.5	Very high	93.5	Very high	155 Å²	155	64 Å²	64	68%	0.68	32%	0.32	S	S	*	.	H	α-helix	trans	-61.8	-46.5	177.1	177.2	-101.4	0	0	0	112	W317 T322 L323	W317-F319 PolarHBondContact O-N 2.99Å; W317-F319 VanDerWaalsContact O-N 3.1Å; F319-T322 PolarHBondContact O-N 2.91Å; F319-L323 HydrophobicContact CE1-CD2 4.17Å; F319-L323 HydrophobicContact CZ-CD2 4.39Å; F319-L323 VanDerWaalsContact O-CB 3.23Å; F319-L323 WeakPolarHBondContact O-CB 3.37Å; F319-L323 PolarHBondContact O-N 3.46Å
320	I	94.2	Very high	93.6	Very high	43 Å²	43	69 Å²	69	22%	0.221	34%	0.342	C	S	.	.	H	α-helix	trans	-66.4	-41.2	-179.5	-69.9	168.3	0	0	0	110.3	I211 V309 W317 L323 S324	I211-I320 HydrophobicContact CG2-CG2 4.14Å; V309-I320 HydrophobicContact CG1-CG2 3.6Å; W317-I320 HydrophobicContact CB-CB 4.46Å; W317-I320 HydrophobicContact CB-CD1 4.34Å; W317-I320 HydrophobicContact CD2-CD1 4.05Å; W317-I320 HydrophobicContact CE3-CD1 3.37Å; W317-I320 HydrophobicContact CG-CD1 4.5Å; W317-I320 HydrophobicContact CZ3-CD1 3.93Å; W317-I320 PolarHBondContact O-N 2.86Å; I320-L323 PolarHBondContact O-N 3.03Å; I320-S324 WeakPolarHBondContact O-CB 3.28Å; I320-S324 PolarHBondContact O-N 3.4Å; I320-S324 PolarHBondContact O-OG 3.31Å
321	H	94.6	Very high	93.7	Very high	33 Å²	33	67.4 Å²	67.4	15%	0.153	33%	0.332	C	S	.	.	H	α-helix	trans	-63.7	-45.6	175.5	-64	174.7	0	0	0	112	T310 T313 W317 N318 S324 W325	T310-H321 HydrophobicContact CG2-CB 4.4Å; T313-H321 PolarHBondContact OG1-CD2 3.14Å; T313-H321 VanDerWaalsContact OG1-CD2 3.23Å; T313-H321 PolarHBondContact OG1-NE2 3.37Å; W317-H321 PolarHBondContact O-N 3.26Å; N318-H321 PolarHBondContact O-N 3.49Å; H321-S324 PolarHBondContact O-N 3.32Å; H321-S324 PolarHBondContact O-OG 2.97Å; H321-W325 VanDerWaalsContact O-CD1 3.24Å; H321-W325 PolarHBondContact O-N 3.48Å
322	T	95.9	Very high	93.8	Very high	84 Å²	84	65.3 Å²	65.3	52%	0.515	32%	0.323	S	S	.	.	H	α-helix	trans	-62.9	-47.1	179	-56	0	0	0	0	109.8	N318 F319 S324 W325 V326	N318-T322 VanDerWaalsContact O-CB 3.29Å; N318-T322 WeakPolarHBondContact O-CB 3.31Å; N318-T322 PolarHBondContact O-N 2.7Å; N318-T322 PolarHBondContact O-OG1 3.37Å; F319-T322 PolarHBondContact O-N 2.91Å; T322-S324 VanDerWaalsContact C-N 3.34Å; T322-S324 PolarHBondContact O-N 3.06Å; T322-W325 PolarHBondContact O-N 3.46Å; T322-V326 HydrophobicContact CG2-CG2 4.33Å; T322-V326 WeakPolarHBondContact O-CB 3.48Å; T322-V326 WeakPolarHBondContact O-CG2 3.26Å; T322-V326 PolarHBondContact O-N 2.95Å
323	L	96.3	Very high	94	Very high	57 Å²	57	69.2 Å²	69.2	30%	0.298	34%	0.34	S	S	.	.	H	α-helix	trans	-59.5	-43.8	177.1	-179.8	62.1	0	0	0	111.6	I211 F319 I320 V326 L327	I211-L323 HydrophobicContact CD1-CD2 4Å; F319-L323 HydrophobicContact CE1-CD2 4.17Å; F319-L323 HydrophobicContact CZ-CD2 4.39Å; F319-L323 VanDerWaalsContact O-CB 3.23Å; F319-L323 WeakPolarHBondContact O-CB 3.37Å; F319-L323 PolarHBondContact O-N 3.46Å; I320-L323 PolarHBondContact O-N 3.03Å; L323-V326 PolarHBondContact O-N 3.43Å; L323-L327 HydrophobicContact CD1-CD1 4.11Å; L323-L327 HydrophobicContact CD1-CG 4.17Å; L323-L327 HydrophobicContact CG-CD1 3.97Å; L323-L327 HydrophobicContact CG-CG 4.44Å; L323-L327 WeakPolarHBondContact O-CB 3.34Å; L323-L327 VanDerWaalsContact O-CG 3.27Å; L323-L327 WeakPolarHBondContact O-CG 3.38Å; L323-L327 PolarHBondContact O-N 2.95Å
324	S	96.8	Very high	94.3	Very high	0 Å²	0	70.8 Å²	70.8	0%	0	35%	0.347	C	S	.	.	H	α-helix	trans	-65.7	-40.9	-178.9	73.1	0	0	0	0	112.2	N306 T310 I320 H321 T322 L327 N328	N306-S324 WeakPolarHBondContact OD1-CB 3.29Å; N306-S324 PolarHBondContact OD1-O 3.49Å; N306-S324 PolarHBondContact OD1-OG 3.5Å; T310-S324 WeakPolarHBondContact CG2-OG 3.48Å; I320-S324 WeakPolarHBondContact O-CB 3.28Å; I320-S324 PolarHBondContact O-N 3.4Å; I320-S324 PolarHBondContact O-OG 3.31Å; H321-S324 PolarHBondContact O-N 3.32Å; H321-S324 PolarHBondContact O-OG 2.97Å; T322-S324 VanDerWaalsContact C-N 3.34Å; T322-S324 PolarHBondContact O-N 3.06Å; S324-L327 PolarHBondContact O-N 3.36Å; S324-N328 WeakPolarHBondContact O-CB 3.48Å; S324-N328 PolarHBondContact O-N 2.71Å
325	W	97.1	Very high	94.5	Very high	119 Å²	119	69.2 Å²	69.2	45%	0.451	34%	0.336	S	S	.	.	H	α-helix	trans	-67.7	-39.9	175.5	-85.4	106.6	0	0	0	112.9	N306 F307 H321 T322 N328 L329	N306-W325 PolarHBondContact OD1-N 3.26Å; F307-W325 HydrophobicContact CD1-CH2 4.45Å; F307-W325 HydrophobicContact CD1-CZ2 4.38Å; F307-W325 AromaticContact CE1-CH2 3.61Å; F307-W325 HydrophobicContact CE1-CH2 3.61Å; F307-W325 AromaticContact CE1-CZ2 3.96Å; F307-W325 HydrophobicContact CE1-CZ2 3.96Å; F307-W325 HydrophobicContact CE1-CZ3 4.37Å; H321-W325 VanDerWaalsContact O-CD1 3.24Å; H321-W325 PolarHBondContact O-N 3.48Å; T322-W325 PolarHBondContact O-N 3.46Å; W325-N328 PolarHBondContact O-N 2.98Å; W325-L329 WeakPolarHBondContact O-CB 3.4Å; W325-L329 PolarHBondContact O-N 3.33Å
326	V	97.6	Very high	94.9	Very high	62 Å²	62	59.2 Å²	59.2	38%	0.376	30%	0.3	S	S	.	.	H	α-helix	trans	-61.5	-49.6	174.6	166.8	0	0	0	0	110.1	T322 L323 N328 L329 F330	T322-V326 HydrophobicContact CG2-CG2 4.33Å; T322-V326 WeakPolarHBondContact O-CB 3.48Å; T322-V326 WeakPolarHBondContact O-CG2 3.26Å; T322-V326 PolarHBondContact O-N 2.95Å; L323-V326 PolarHBondContact O-N 3.43Å; V326-N328 VanDerWaalsContact C-N 3.28Å; V326-N328 PolarHBondContact O-N 2.89Å; V326-L329 PolarHBondContact O-N 3.22Å; V326-F330 HydrophobicContact CG1-CD2 3.59Å; V326-F330 HydrophobicContact CG1-CE2 3.76Å; V326-F330 VanDerWaalsContact O-CD2 3.3Å; V326-F330 WeakPolarHBondContact O-CD2 3.44Å; V326-F330 PolarHBondContact O-N 3.45Å
327	L	97.1	Very high	95.3	Very high	19 Å²	19	56.1 Å²	56.1	10%	0.099	27%	0.268	C	S	.	.	H	α-helix	trans	-60.8	-37.3	176.5	-71.6	170.7	0	0	0	112.2	C204 I207 L208 I211 L323 S324 G331	C204-L327 HydrophobicContact CB-CD2 4.21Å; I207-L327 HydrophobicContact CB-CD1 4.24Å; I207-L327 HydrophobicContact CG2-CD1 3.57Å; L208-L327 HydrophobicContact CD1-CB 4Å; L208-L327 HydrophobicContact CD2-CB 4.19Å; L208-L327 HydrophobicContact CD2-CD1 4.08Å; L208-L327 HydrophobicContact CG-CB 3.93Å; L208-L327 HydrophobicContact CG-CD1 3.98Å; I211-L327 HydrophobicContact CD1-CD1 4.21Å; L323-L327 HydrophobicContact CD1-CD1 4.11Å; L323-L327 HydrophobicContact CD1-CG 4.17Å; L323-L327 HydrophobicContact CG-CD1 3.97Å; L323-L327 HydrophobicContact CG-CG 4.44Å; L323-L327 WeakPolarHBondContact O-CB 3.34Å; L323-L327 VanDerWaalsContact O-CG 3.27Å; L323-L327 WeakPolarHBondContact O-CG 3.38Å; L323-L327 PolarHBondContact O-N 2.95Å; S324-L327 PolarHBondContact O-N 3.36Å; L327-G331 WeakPolarHBondContact O-CA 3.38Å; L327-G331 PolarHBondContact O-N 3.38Å
328	N	97.3	Very high	95.3	Very high	5 Å²	5	51.2 Å²	51.2	3%	0.027	25%	0.25	C	S	.	.	H	α-helix	trans	-64.8	-47.6	175.5	-176.8	64.7	0	0	0	112.2	I302 T303 N306 S324 W325 V326 G331 I332	I302-N328 HydrophobicContact CG2-CB 4.28Å; I302-N328 WeakPolarHBondContact CG2-OD1 3.48Å; T303-N328 VanDerWaalsContact CA-OD1 3.23Å; T303-N328 WeakPolarHBondContact CA-OD1 3.29Å; T303-N328 PolarHBondContact N-OD1 3.01Å; T303-N328 PolarHBondContact OG1-OD1 3.5Å; N306-N328 HydrophobicContact CB-CB 3.94Å; S324-N328 WeakPolarHBondContact O-CB 3.48Å; S324-N328 PolarHBondContact O-N 2.71Å; W325-N328 PolarHBondContact O-N 2.98Å; V326-N328 VanDerWaalsContact C-N 3.28Å; V326-N328 PolarHBondContact O-N 2.89Å; N328-G331 PolarHBondContact O-N 3.45Å; N328-I332 WeakPolarHBondContact O-CB 3.15Å; N328-I332 VanDerWaalsContact O-CG1 3.29Å; N328-I332 WeakPolarHBondContact O-CG1 2.8Å; N328-I332 PolarHBondContact O-N 3.48Å
329	L	96.9	Very high	95.2	Very high	119 Å²	119	47.3 Å²	47.3	62%	0.623	23%	0.229	S	C	*	.	H	α-helix	trans	-63.7	-48.6	179.7	-177.9	66.6	0	0	0	111.6	W325 V326 I332 F333	W325-L329 WeakPolarHBondContact O-CB 3.4Å; W325-L329 PolarHBondContact O-N 3.33Å; V326-L329 PolarHBondContact O-N 3.22Å; L329-I332 PolarHBondContact O-N 3.26Å; L329-F333 PolarHBondContact O-N 2.87Å
330	F	96.6	Very high	94.8	Very high	104 Å²	104	41.4 Å²	41.4	46%	0.456	20%	0.203	S	C	.	.	H	α-helix	trans	-67.3	-38.5	177.8	-80.8	-71	0	0	0	112.1	V326 I332 F333 F334	V326-F330 HydrophobicContact CG1-CD2 3.59Å; V326-F330 HydrophobicContact CG1-CE2 3.76Å; V326-F330 VanDerWaalsContact O-CD2 3.3Å; V326-F330 WeakPolarHBondContact O-CD2 3.44Å; V326-F330 PolarHBondContact O-N 3.45Å; F330-I332 PolarHBondContact O-N 3.42Å; F330-F333 PolarHBondContact O-N 2.76Å; F330-F334 HydrophobicContact CB-CD2 4.31Å; F330-F334 HydrophobicContact CB-CE2 3.94Å; F330-F334 HydrophobicContact CD1-CE2 4.46Å; F330-F334 HydrophobicContact CD1-CZ 4.26Å; F330-F334 WeakPolarHBondContact O-CB 3.23Å; F330-F334 WeakPolarHBondContact O-CD2 3.29Å; F330-F334 VanDerWaalsContact O-CG 3.22Å; F330-F334 WeakPolarHBondContact O-CG 3.01Å; F330-F334 PolarHBondContact O-N 2.9Å
331	G	96.3	Very high	94.6	Very high	0 Å²	0	39.5 Å²	39.5	0%	0	19%	0.193	C	C	.	.	H	α-helix	trans	-58.1	-47.5	174.2	0	0	0	0	0	112	L327 N328 F334 I335	L327-G331 WeakPolarHBondContact O-CA 3.38Å; L327-G331 PolarHBondContact O-N 3.38Å; N328-G331 PolarHBondContact O-N 3.45Å; G331-F334 PolarHBondContact O-N 3.32Å; G331-I335 VanDerWaalsContact O-CG1 3.28Å; G331-I335 WeakPolarHBondContact O-CG1 3.42Å; G331-I335 PolarHBondContact O-N 3.45Å
332	I	95.8	Very high	94.5	Very high	28 Å²	28	38.2 Å²	38.2	14%	0.144	19%	0.187	C	C	.	.	H	α-helix	trans	-60.4	-46.4	175.1	-73.3	171.3	0	0	0	111.3	T299 N328 L329 F330 F334 I335 L336 V346 F350	T299-I332 HydrophobicContact CG2-CD1 4.44Å; T299-I332 HydrophobicContact CG2-CG1 4.18Å; N328-I332 WeakPolarHBondContact O-CB 3.15Å; N328-I332 VanDerWaalsContact O-CG1 3.29Å; N328-I332 WeakPolarHBondContact O-CG1 2.8Å; N328-I332 PolarHBondContact O-N 3.48Å; L329-I332 PolarHBondContact O-N 3.26Å; F330-I332 PolarHBondContact O-N 3.42Å; I332-F334 PolarHBondContact O-N 3.39Å; I332-I335 PolarHBondContact O-N 3.25Å; I332-L336 PolarHBondContact O-N 2.93Å; I332-V346 HydrophobicContact CG2-CG1 3.67Å; I332-F350 HydrophobicContact CD1-CD2 3.9Å; I332-F350 HydrophobicContact CD1-CE2 4.44Å
333	F	95.3	Very high	94.4	Very high	86 Å²	86	35.5 Å²	35.5	38%	0.377	17%	0.171	S	C	.	.	H	α-helix	trans	-59.7	-45.1	177.1	171.4	-99.7	0	0	0	112.1	F187 L329 F330 I335 L336 A337	F187-F333 HydrophobicContact CZ-CD2 4.47Å; F187-F333 HydrophobicContact CZ-CE2 4.4Å; L329-F333 PolarHBondContact O-N 2.87Å; F330-F333 PolarHBondContact O-N 2.76Å; F333-I335 PolarHBondContact O-N 2.87Å; F333-L336 PolarHBondContact O-N 3Å; F333-A337 HydrophobicContact CE1-CB 4.34Å; F333-A337 HydrophobicContact CZ-CB 4.38Å; F333-A337 WeakPolarHBondContact O-CB 3.26Å; F333-A337 PolarHBondContact O-N 2.88Å
334	F	95.6	Very high	94.2	Very high	35 Å²	35	37.3 Å²	37.3	15%	0.154	18%	0.18	C	C	.	.	H	α-helix	trans	-67	-33.9	-179.6	-71.8	-37.9	0	0	0	113.2	W196 A197 M200 A201 F330 G331 I332 L336 A337 A338	W196-F334 HydrophobicContact CH2-CE1 4.26Å; W196-F334 HydrophobicContact CZ3-CD1 4.37Å; W196-F334 AromaticContact CZ3-CE1 3.88Å; W196-F334 HydrophobicContact CZ3-CE1 3.88Å; W196-F334 HydrophobicContact CZ3-CZ 4.42Å; A197-F334 HydrophobicContact CB-CB 4.27Å; A197-F334 HydrophobicContact CB-CD1 4.17Å; A197-F334 WeakPolarHBondContact CB-O 3.31Å; A197-F334 WeakPolarHBondContact O-CB 3.46Å; M200-F334 HydrophobicContact CB-CD2 3.78Å; M200-F334 HydrophobicContact CB-CE2 3.9Å; M200-F334 HydrophobicContact CB-CG 4.16Å; M200-F334 HydrophobicContact CB-CZ 4.38Å; A201-F334 HydrophobicContact CB-CB 3.77Å; F330-F334 HydrophobicContact CB-CD2 4.31Å; F330-F334 HydrophobicContact CB-CE2 3.94Å; F330-F334 HydrophobicContact CD1-CE2 4.46Å; F330-F334 HydrophobicContact CD1-CZ 4.26Å; F330-F334 WeakPolarHBondContact O-CB 3.23Å; F330-F334 WeakPolarHBondContact O-CD2 3.29Å; F330-F334 VanDerWaalsContact O-CG 3.22Å; F330-F334 WeakPolarHBondContact O-CG 3.01Å; F330-F334 PolarHBondContact O-N 2.9Å; G331-F334 PolarHBondContact O-N 3.32Å; I332-F334 PolarHBondContact O-N 3.39Å; F334-L336 VanDerWaalsContact C-N 3.35Å; F334-A337 PolarHBondContact O-N 3.22Å; F334-A338 WeakPolarHBondContact O-CB 3.3Å; F334-A338 PolarHBondContact O-N 2.87Å; F334-A338 VanDerWaalsContact O-N 3.09Å
335	I	93.8	Very high	94	Very high	0 Å²	0	37.4 Å²	37.4	0%	0	18%	0.181	C	C	.	.	H	α-helix	trans	-60	-47.3	171.9	-70	166.7	0	0	0	110.3	A201 H298 T299 I302 G331 I332 F333 A338 H341 V346	A201-I335 HydrophobicContact CB-CG1 3.71Å; H298-I335 HydrophobicContact CB-CD1 3.64Å; H298-I335 HydrophobicContact CB-CG1 4.33Å; T299-I335 WeakPolarHBondContact OG1-CD1 3.39Å; I302-I335 HydrophobicContact CD1-CD1 4.13Å; G331-I335 VanDerWaalsContact O-CG1 3.28Å; G331-I335 WeakPolarHBondContact O-CG1 3.42Å; G331-I335 PolarHBondContact O-N 3.45Å; I332-I335 PolarHBondContact O-N 3.25Å; F333-I335 PolarHBondContact O-N 2.87Å; I335-A338 PolarHBondContact O-N 2.91Å; I335-H341 HydrophobicContact CG2-CB 4.11Å; I335-V346 HydrophobicContact CG2-CG2 3.72Å
336	L	93.8	Very high	93.9	Very high	21 Å²	21	32 Å²	32	11%	0.11	16%	0.161	C	C	.	.	H	α-helix	trans	-66.8	-45.1	179	-66.1	173	0	0	0	111.8	F187 I332 F333 F334 A338 H339 V346	F187-L336 HydrophobicContact CD1-CB 3.88Å; F187-L336 HydrophobicContact CE1-CB 3.38Å; F187-L336 HydrophobicContact CE1-CD1 4.36Å; F187-L336 HydrophobicContact CE1-CG 4.41Å; F187-L336 HydrophobicContact CE2-CD1 4.29Å; F187-L336 HydrophobicContact CZ-CB 3.81Å; F187-L336 HydrophobicContact CZ-CD1 4.19Å; I332-L336 PolarHBondContact O-N 2.93Å; F333-L336 PolarHBondContact O-N 3Å; F334-L336 VanDerWaalsContact C-N 3.35Å; L336-A338 PolarHBondContact O-N 3.38Å; L336-H339 PolarHBondContact O-CD2 3.09Å; L336-H339 VanDerWaalsContact O-CD2 3.29Å; L336-H339 PolarHBondContact O-N 2.99Å; L336-V346 HydrophobicContact CD1-CG1 4.47Å; L336-V346 HydrophobicContact CD2-CB 3.85Å; L336-V346 HydrophobicContact CD2-CG1 4.24Å; L336-V346 HydrophobicContact CD2-CG2 3.55Å; L336-V346 HydrophobicContact CG-CB 4.41Å; L336-V346 HydrophobicContact CG-CG1 4.27Å; L336-V346 HydrophobicContact CG-CG2 4.15Å
337	A	93.6	Very high	93.7	Very high	0 Å²	0	35.5 Å²	35.5	0%	0	17%	0.171	C	C	.	.	H	α-helix	trans	-64.9	-20.7	-179.4	0	0	0	0	0	113.8	I194 A197 F333 F334 H339	I194-A337 HydrophobicContact CD1-CB 4.26Å; I194-A337 PolarHBondContact N-O 2.97Å; A197-A337 HydrophobicContact CB-CB 4.03Å; F333-A337 HydrophobicContact CE1-CB 4.34Å; F333-A337 HydrophobicContact CZ-CB 4.38Å; F333-A337 WeakPolarHBondContact O-CB 3.26Å; F333-A337 PolarHBondContact O-N 2.88Å; F334-A337 PolarHBondContact O-N 3.22Å; A337-H339 VanDerWaalsContact C-N 3.29Å; A337-H339 PolarHBondContact O-CD2 2.91Å
338	A	90.6	Very high	93.6	Very high	2 Å²	2	37.9 Å²	37.9	2%	0.017	18%	0.184	C	C	.	.	T	Hydrogen-bonded Turn	trans	-73.6	-20.7	174.2	0	0	0	0	0	113.7	R193 A197 F198 F334 I335 L336 E340	R193-A338 PolarHBondContact NE-O 3.41Å; A197-A338 HydrophobicContact CB-CB 4.32Å; F198-A338 HydrophobicContact CB-CB 3.65Å; F198-A338 HydrophobicContact CD2-CB 3.95Å; F198-A338 HydrophobicContact CG-CB 4.24Å; F334-A338 WeakPolarHBondContact O-CB 3.3Å; F334-A338 PolarHBondContact O-N 2.87Å; F334-A338 VanDerWaalsContact O-N 3.09Å; I335-A338 PolarHBondContact O-N 2.91Å; L336-A338 PolarHBondContact O-N 3.38Å; A338-E340 HydrophobicContact CB-CG 4.06Å; A338-E340 PolarHBondContact O-N 3.32Å
339	H	90.1	Very high	93.4	Very high	22 Å²	22	37.7 Å²	37.7	10%	0.102	18%	0.183	C	C	.	.	T	Hydrogen-bonded Turn	trans	62	27.8	-174.1	-63.4	-150.7	0	0	0	113.4	L188 V191 R193 H255 L336 A337	L188-H339 HydrophobicContact CD2-CB 3.62Å; L188-H339 PolarHBondContact O-CE1 3.08Å; V191-H339 PolarHBondContact O-CE1 3.11Å; V191-H339 PolarHBondContact O-NE2 3.06Å; R193-H339 HydrophobicContact CB-CB 4.48Å; R193-H339 HydrophobicContact CG-CB 4.19Å; H255-H339 PolarHBondContact CE1-O 2.95Å; L336-H339 PolarHBondContact O-CD2 3.09Å; L336-H339 VanDerWaalsContact O-CD2 3.29Å; L336-H339 PolarHBondContact O-N 2.99Å; A337-H339 VanDerWaalsContact C-N 3.29Å; A337-H339 PolarHBondContact O-CD2 2.91Å
340	E	84.7	Confident	93.4	Very high	30 Å²	30	35.3 Å²	35.3	14%	0.14	17%	0.168	C	C	.	.	S	Bend	trans	-93.4	-17.4	177.7	-63.5	-163.7	175.9	0	0	112.9	F198 P252 Y293 A338	F198-E340 VanDerWaalsContact CD1-OE2 3.27Å; F198-E340 WeakPolarHBondContact CD1-OE2 3.38Å; F198-E340 HydrophobicContact CD2-CB 4.25Å; F198-E340 HydrophobicContact CD2-CG 4.3Å; F198-E340 WeakPolarHBondContact CD2-OE2 3.26Å; F198-E340 VanDerWaalsContact CE1-OE2 3.27Å; F198-E340 WeakPolarHBondContact CE1-OE2 3.48Å; F198-E340 HydrophobicContact CE2-CB 4.25Å; F198-E340 WeakPolarHBondContact CE2-OE2 3.34Å; F198-E340 VanDerWaalsContact CG-OE2 3.3Å; F198-E340 WeakPolarHBondContact CG-OE2 3.39Å; F198-E340 VanDerWaalsContact CZ-OE2 3.29Å; F198-E340 WeakPolarHBondContact CZ-OE2 3.36Å; P252-E340 WeakPolarHBondContact CG-O 3.35Å; Y293-E340 WeakPolarHBondContact CD1-O 3.49Å; Y293-E340 WeakPolarHBondContact CE1-O 3.47Å; A338-E340 HydrophobicContact CB-CG 4.06Å; A338-E340 PolarHBondContact O-N 3.32Å
341	H	90.4	Very high	93.3	Very high	4 Å²	4	35.9 Å²	35.9	2%	0.019	17%	0.167	C	C	.	.	S	Bend	trans	-130.8	150.2	175.1	-73.5	-79	0	0	0	110.6	D292 I335 D345 V346	D292-H341 IonicContact OD2-CE1 3.28Å; I335-H341 HydrophobicContact CG2-CB 4.11Å; H341-D345 HydrophobicContact CB-CB 4.43Å; H341-D345 IonicContact CE1-OD2 3.76Å; H341-D345 IonicContact CG-OD2 3.31Å; H341-D345 IonicContact ND1-OD2 2.89Å; H341-D345 PolarHBondContact ND1-OD2 3.13Å; H341-V346 HydrophobicContact CB-CG2 4.14Å
342	Y	92.4	Very high	93.3	Very high	5 Å²	5	37.8 Å²	37.8	2%	0.02	18%	0.177	C	C	.	.			trans	-69.5	154.2	169.3	-68.1	-74.9	0	0	0	111.3	L183 D185 L188 L249 S250 P252 I344 D345 V346	L183-Y342 HydrophobicContact CB-CE1 3.94Å; L183-Y342 PolarHBondContact N-OH 3.29Å; L183-Y342 VanDerWaalsContact N-OH 3.15Å; D185-Y342 HydrophobicContact CB-CD1 4.24Å; L188-Y342 HydrophobicContact CD1-CD1 3.8Å; L188-Y342 HydrophobicContact CD1-CE1 4.34Å; L249-Y342 HydrophobicContact CB-CE2 4.42Å; L249-Y342 HydrophobicContact CD1-CD2 4.49Å; S250-Y342 VanDerWaalsContact O-CE2 3.25Å; S250-Y342 WeakPolarHBondContact O-CE2 3.24Å; S250-Y342 PolarHBondContact O-OH 2.73Å; S250-Y342 PolarHBondContact OG-OH 3.37Å; P252-Y342 HydrophobicContact CB-CD1 4.16Å; P252-Y342 HydrophobicContact CB-CD2 4.32Å; P252-Y342 HydrophobicContact CB-CE1 3.87Å; P252-Y342 HydrophobicContact CB-CE2 4.04Å; P252-Y342 HydrophobicContact CB-CG 4.37Å; Y342-I344 VanDerWaalsContact C-N 3.28Å; Y342-I344 PolarHBondContact O-N 2.6Å; Y342-D345 WeakPolarHBondContact O-CB 3.29Å; Y342-D345 PolarHBondContact O-N 2.67Å; Y342-D345 VanDerWaalsContact O-N 3.07Å; Y342-V346 PolarHBondContact O-N 3.11Å
343	S	93.6	Very high	93.2	Very high	27 Å²	27	36.4 Å²	36.4	19%	0.189	17%	0.17	C	C	.	.	H	α-helix	trans	-61.2	-39.1	175.8	-57.1	0	0	0	0	112.5	D185 F187 D345 V346 F347	D185-S343 VanDerWaalsContact CG-OG 3.28Å; D185-S343 WeakPolarHBondContact OD1-CB 3.48Å; D185-S343 PolarHBondContact OD1-OG 3.07Å; D185-S343 VanDerWaalsContact OD2-CB 3.26Å; D185-S343 WeakPolarHBondContact OD2-CB 3.38Å; D185-S343 PolarHBondContact OD2-N 3.36Å; D185-S343 PolarHBondContact OD2-OG 2.62Å; D185-S343 VanDerWaalsContact OD2-OG 3.13Å; F187-S343 WeakPolarHBondContact CB-OG 3.42Å; S343-D345 PolarHBondContact O-N 3.38Å; S343-V346 PolarHBondContact O-N 3.43Å; S343-F347 WeakPolarHBondContact O-CB 3.49Å; S343-F347 PolarHBondContact O-N 3.31Å
344	I	92.8	Very high	93.2	Very high	95 Å²	95	34 Å²	34	49%	0.487	16%	0.162	S	C	.	.	H	α-helix	trans	-63.4	-33.7	176.5	-169	60	0	0	0	111.5	Y342 F347 I348	Y342-I344 VanDerWaalsContact C-N 3.28Å; Y342-I344 PolarHBondContact O-N 2.6Å; I344-F347 HydrophobicContact CD1-CD1 4.36Å; I344-F347 PolarHBondContact O-N 2.65Å; I344-I348 HydrophobicContact CD1-CD1 3.95Å; I344-I348 HydrophobicContact CD1-CG1 4.03Å; I344-I348 HydrophobicContact CG1-CD1 3.74Å; I344-I348 HydrophobicContact CG1-CG1 4.21Å; I344-I348 WeakPolarHBondContact O-CB 3.3Å; I344-I348 VanDerWaalsContact O-CG1 3.29Å; I344-I348 WeakPolarHBondContact O-CG1 3.4Å; I344-I348 PolarHBondContact O-N 2.94Å
345	D	92.3	Very high	93.2	Very high	3 Å²	3	36.8 Å²	36.8	2%	0.016	17%	0.172	C	C	.	.	H	α-helix	trans	-63.1	-49.9	179.8	-171.7	6.9	0	0	0	110.7	Y293 F295 S296 H341 Y342 S343 A349	Y293-D345 WeakPolarHBondContact CA-OD2 3.18Å; Y293-D345 WeakPolarHBondContact O-CB 3.35Å; Y293-D345 VanDerWaalsContact O-OD2 3.12Å; F295-D345 WeakPolarHBondContact CA-OD1 3.48Å; F295-D345 PolarHBondContact N-OD1 3.34Å; S296-D345 PolarHBondContact N-OD1 3.27Å; H341-D345 HydrophobicContact CB-CB 4.43Å; H341-D345 IonicContact CE1-OD2 3.76Å; H341-D345 IonicContact CG-OD2 3.31Å; H341-D345 IonicContact ND1-OD2 2.89Å; H341-D345 PolarHBondContact ND1-OD2 3.13Å; Y342-D345 WeakPolarHBondContact O-CB 3.29Å; Y342-D345 PolarHBondContact O-N 2.67Å; Y342-D345 VanDerWaalsContact O-N 3.07Å; S343-D345 PolarHBondContact O-N 3.38Å; D345-A349 WeakPolarHBondContact O-CB 3.35Å; D345-A349 PolarHBondContact O-N 3.05Å
346	V	94.4	Very high	93.1	Very high	5 Å²	5	38.8 Å²	38.8	3%	0.03	18%	0.182	C	C	.	.	H	α-helix	trans	-65.2	-41.8	176.7	176.7	0	0	0	0	111.7	T299 I332 I335 L336 H341 Y342 S343 A349 F350	T299-V346 HydrophobicContact CG2-CG1 4.07Å; I332-V346 HydrophobicContact CG2-CG1 3.67Å; I335-V346 HydrophobicContact CG2-CG2 3.72Å; L336-V346 HydrophobicContact CD1-CG1 4.47Å; L336-V346 HydrophobicContact CD2-CB 3.85Å; L336-V346 HydrophobicContact CD2-CG1 4.24Å; L336-V346 HydrophobicContact CD2-CG2 3.55Å; L336-V346 HydrophobicContact CG-CB 4.41Å; L336-V346 HydrophobicContact CG-CG1 4.27Å; L336-V346 HydrophobicContact CG-CG2 4.15Å; H341-V346 HydrophobicContact CB-CG2 4.14Å; Y342-V346 PolarHBondContact O-N 3.11Å; S343-V346 PolarHBondContact O-N 3.43Å; V346-A349 PolarHBondContact O-N 2.69Å; V346-F350 WeakPolarHBondContact O-CB 3.39Å; V346-F350 PolarHBondContact O-N 3.47Å
347	F	94.7	Very high	93.1	Very high	135 Å²	135	38.7 Å²	38.7	59%	0.592	18%	0.181	S	C	*	.	H	α-helix	trans	-63.5	-48.4	178.8	178	-100.2	0	0	0	112.5	S343 I344 A349 F350 Y351	S343-F347 WeakPolarHBondContact O-CB 3.49Å; S343-F347 PolarHBondContact O-N 3.31Å; I344-F347 HydrophobicContact CD1-CD1 4.36Å; I344-F347 PolarHBondContact O-N 2.65Å; F347-A349 VanDerWaalsContact C-N 3.33Å; F347-A349 PolarHBondContact O-N 3.3Å; F347-F350 PolarHBondContact O-N 3.01Å; F347-Y351 WeakPolarHBondContact O-CB 3.5Å; F347-Y351 PolarHBondContact O-N 3.15Å
348	I	94.1	Very high	93	Very high	70 Å²	70	42.6 Å²	42.6	36%	0.359	20%	0.201	S	C	.	.	H	α-helix	trans	-65.3	-40.2	178.5	-65.7	175	0	0	0	110.2	F295 I344 F350 Y351 I352	F295-I348 HydrophobicContact CD2-CG2 4.02Å; F295-I348 HydrophobicContact CE2-CG2 4.42Å; I344-I348 HydrophobicContact CD1-CD1 3.95Å; I344-I348 HydrophobicContact CD1-CG1 4.03Å; I344-I348 HydrophobicContact CG1-CD1 3.74Å; I344-I348 HydrophobicContact CG1-CG1 4.21Å; I344-I348 WeakPolarHBondContact O-CB 3.3Å; I344-I348 VanDerWaalsContact O-CG1 3.29Å; I344-I348 WeakPolarHBondContact O-CG1 3.4Å; I344-I348 PolarHBondContact O-N 2.94Å; I348-F350 PolarHBondContact O-N 3.24Å; I348-Y351 PolarHBondContact O-N 3.23Å; I348-I352 HydrophobicContact CG2-CD1 3.61Å; I348-I352 HydrophobicContact CG2-CG1 4.08Å; I348-I352 WeakPolarHBondContact O-CG1 3.35Å; I348-I352 PolarHBondContact O-N 3.19Å
349	A	94.6	Very high	93	Very high	0 Å²	0	48.1 Å²	48.1	0%	0	22%	0.223	C	C	.	.	H	α-helix	trans	-54.9	-50.7	173.8	0	0	0	0	0	112.6	F295 T299 V300 D345 V346 F347 T353	F295-A349 HydrophobicContact CD2-CB 4.24Å; F295-A349 HydrophobicContact CE2-CB 4.19Å; T299-A349 HydrophobicContact CG2-CB 3.71Å; V300-A349 HydrophobicContact CG2-CB 4.13Å; D345-A349 WeakPolarHBondContact O-CB 3.35Å; D345-A349 PolarHBondContact O-N 3.05Å; V346-A349 PolarHBondContact O-N 2.69Å; F347-A349 VanDerWaalsContact C-N 3.33Å; F347-A349 PolarHBondContact O-N 3.3Å; A349-T353 VanDerWaalsContact O-CB 3.23Å; A349-T353 WeakPolarHBondContact O-CB 3.48Å; A349-T353 PolarHBondContact O-N 2.86Å; A349-T353 VanDerWaalsContact O-N 3.13Å; A349-T353 PolarHBondContact O-OG1 2.92Å
350	F	95.4	Very high	92.9	Very high	70 Å²	70	47.9 Å²	47.9	31%	0.307	22%	0.221	S	C	.	.	H	α-helix	trans	-61.9	-45.2	176.1	179.9	-100.1	0	0	0	112	T299 T303 F307 I332 V346 F347 I348 T354	T299-F350 HydrophobicContact CG2-CB 4.31Å; T303-F350 HydrophobicContact CG2-CD2 3.72Å; T303-F350 HydrophobicContact CG2-CE2 3.91Å; F307-F350 HydrophobicContact CZ-CE2 4.38Å; I332-F350 HydrophobicContact CD1-CD2 3.9Å; I332-F350 HydrophobicContact CD1-CE2 4.44Å; V346-F350 WeakPolarHBondContact O-CB 3.39Å; V346-F350 PolarHBondContact O-N 3.47Å; F347-F350 PolarHBondContact O-N 3.01Å; I348-F350 PolarHBondContact O-N 3.24Å; F350-T354 WeakPolarHBondContact O-CB 3.49Å; F350-T354 PolarHBondContact O-N 3.35Å; F350-T354 PolarHBondContact O-OG1 3.41Å
351	Y	95.9	Very high	93.1	Very high	116 Å²	116	46.8 Å²	46.8	46%	0.455	22%	0.216	S	C	.	.	H	α-helix	trans	-62.6	-53.6	-178.2	-180	-99.3	0	0	0	112.8	F347 I348 T353 T354 R355	F347-Y351 WeakPolarHBondContact O-CB 3.5Å; F347-Y351 PolarHBondContact O-N 3.15Å; I348-Y351 PolarHBondContact O-N 3.23Å; Y351-T353 VanDerWaalsContact C-N 3.34Å; Y351-T353 PolarHBondContact O-N 3.02Å; Y351-T354 PolarHBondContact O-N 3.14Å; Y351-R355 HydrophobicContact CD1-CG 4.32Å; Y351-R355 HydrophobicContact CD2-CG 4.35Å; Y351-R355 HydrophobicContact CE1-CG 3.93Å; Y351-R355 HydrophobicContact CE2-CG 3.97Å; Y351-R355 VanDerWaalsContact O-CG 3.32Å; Y351-R355 WeakPolarHBondContact O-CG 3.49Å; Y351-R355 PolarHBondContact O-N 2.89Å
352	I	94.8	Very high	92.9	Very high	39 Å²	39	49.7 Å²	49.7	20%	0.2	23%	0.234	C	C	.	.	H	α-helix	trans	-63.6	-42.5	-178.7	-68.2	-178.8	0	0	0	110.4	L239 F295 I348 T354 R355 L356	L239-I352 HydrophobicContact CD2-CD1 4.19Å; L239-I352 HydrophobicContact CD2-CG2 4.16Å; F295-I352 HydrophobicContact CD2-CD1 4.08Å; F295-I352 HydrophobicContact CE2-CB 3.67Å; F295-I352 HydrophobicContact CE2-CD1 3.64Å; F295-I352 HydrophobicContact CE2-CG1 4.07Å; F295-I352 HydrophobicContact CE2-CG2 3.95Å; F295-I352 HydrophobicContact CZ-CB 4.05Å; F295-I352 HydrophobicContact CZ-CD1 4.49Å; F295-I352 HydrophobicContact CZ-CG2 3.89Å; I348-I352 HydrophobicContact CG2-CD1 3.61Å; I348-I352 HydrophobicContact CG2-CG1 4.08Å; I348-I352 WeakPolarHBondContact O-CG1 3.35Å; I348-I352 PolarHBondContact O-N 3.19Å; I352-T354 PolarHBondContact O-N 3.14Å; I352-R355 PolarHBondContact O-N 3.24Å; I352-L356 HydrophobicContact CG2-CD1 3.57Å; I352-L356 HydrophobicContact CG2-CG 4.24Å; I352-L356 WeakPolarHBondContact O-CB 3.25Å; I352-L356 WeakPolarHBondContact O-CG 3.34Å; I352-L356 PolarHBondContact O-N 3.45Å
353	T	95.4	Very high	92.4	Very high	0 Å²	0	50.5 Å²	50.5	0%	0	24%	0.239	C	C	.	.	H	α-helix	trans	-59.5	-47.4	177.7	-58.6	0	0	0	0	110.9	T303 M304 A349 Y351 F357	T303-T353 HydrophobicContact CG2-CG2 3.84Å; M304-T353 HydrophobicContact CB-CG2 4.09Å; M304-T353 HydrophobicContact CE-CG2 3.88Å; M304-T353 HydrophobicContact SD-CG2 4.22Å; A349-T353 VanDerWaalsContact O-CB 3.23Å; A349-T353 WeakPolarHBondContact O-CB 3.48Å; A349-T353 PolarHBondContact O-N 2.86Å; A349-T353 VanDerWaalsContact O-N 3.13Å; A349-T353 PolarHBondContact O-OG1 2.92Å; Y351-T353 VanDerWaalsContact C-N 3.34Å; Y351-T353 PolarHBondContact O-N 3.02Å; T353-F357 VanDerWaalsContact O-CB 3.24Å; T353-F357 WeakPolarHBondContact O-CB 3.31Å; T353-F357 PolarHBondContact O-N 3.22Å
354	T	94.9	Very high	91.9	Very high	34 Å²	34	49.2 Å²	49.2	21%	0.209	23%	0.23	C	C	.	.	H	α-helix	trans	-61.7	-45.5	177.5	-55.7	0	0	0	0	112.2	F307 F350 Y351 I352 L358	F307-T354 HydrophobicContact CE2-CG2 4.17Å; F307-T354 WeakPolarHBondContact CE2-OG1 3.29Å; F307-T354 HydrophobicContact CZ-CG2 4.07Å; F307-T354 WeakPolarHBondContact CZ-OG1 3.32Å; F350-T354 WeakPolarHBondContact O-CB 3.49Å; F350-T354 PolarHBondContact O-N 3.35Å; F350-T354 PolarHBondContact O-OG1 3.41Å; Y351-T354 PolarHBondContact O-N 3.14Å; I352-T354 PolarHBondContact O-N 3.14Å; T354-L358 WeakPolarHBondContact O-CB 3.35Å; T354-L358 PolarHBondContact O-N 3.13Å
355	R	94.9	Very high	91.3	Very high	94 Å²	94	47.3 Å²	47.3	36%	0.355	22%	0.22	S	C	.	.	H	α-helix	trans	-68.2	-45	-179.1	-67.9	-63.4	178	-136.9	-0.3	112.2	Y351 I352 F357 L358 Y359	Y351-R355 HydrophobicContact CD1-CG 4.32Å; Y351-R355 HydrophobicContact CD2-CG 4.35Å; Y351-R355 HydrophobicContact CE1-CG 3.93Å; Y351-R355 HydrophobicContact CE2-CG 3.97Å; Y351-R355 VanDerWaalsContact O-CG 3.32Å; Y351-R355 WeakPolarHBondContact O-CG 3.49Å; Y351-R355 PolarHBondContact O-N 2.89Å; I352-R355 PolarHBondContact O-N 3.24Å; R355-F357 VanDerWaalsContact C-N 3.34Å; R355-F357 PolarHBondContact O-N 3.19Å; R355-L358 PolarHBondContact O-N 3.3Å; R355-Y359 HydrophobicContact CB-CE2 4.2Å; R355-Y359 WeakPolarHBondContact O-CB 3.37Å; R355-Y359 WeakPolarHBondContact O-CD2 3.04Å; R355-Y359 PolarHBondContact O-N 3.26Å
356	L	92.3	Very high	90.7	Very high	42 Å²	42	49.6 Å²	49.6	22%	0.22	23%	0.234	C	C	.	.	H	α-helix	trans	-63.7	-41.8	177.3	-75.9	172.2	0	0	0	111.5	L232 V236 I352 Y360	L232-L356 HydrophobicContact CD2-CB 4.47Å; V236-L356 HydrophobicContact CG2-CD1 3.5Å; V236-L356 VanDerWaalsContact CG2-CD1 3.5Å; I352-L356 HydrophobicContact CG2-CD1 3.57Å; I352-L356 HydrophobicContact CG2-CG 4.24Å; I352-L356 WeakPolarHBondContact O-CB 3.25Å; I352-L356 WeakPolarHBondContact O-CG 3.34Å; I352-L356 PolarHBondContact O-N 3.45Å; L356-Y360 WeakPolarHBondContact O-CB 3.32Å; L356-Y360 PolarHBondContact O-N 2.96Å
357	F	94	Very high	89.3	Confident	20 Å²	20	56.2 Å²	56.2	9%	0.088	26%	0.259	C	S	.	.	H	α-helix	trans	-59.8	-49.9	174.9	-174.7	-87	0	0	0	111.6	L232 M304 F307 F308 E311 T353 R355 Y360 H361	L232-F357 HydrophobicContact CD1-CD2 4.21Å; M304-F357 HydrophobicContact SD-CD2 3.97Å; F307-F357 HydrophobicContact CB-CD1 4.05Å; F307-F357 HydrophobicContact CB-CD2 3.75Å; F307-F357 HydrophobicContact CB-CE1 3.93Å; F307-F357 HydrophobicContact CB-CE2 3.59Å; F307-F357 HydrophobicContact CB-CG 3.98Å; F307-F357 HydrophobicContact CB-CZ 3.7Å; F307-F357 HydrophobicContact CD2-CB 4.02Å; F307-F357 HydrophobicContact CD2-CD1 4.22Å; F307-F357 HydrophobicContact CD2-CD2 4.3Å; F307-F357 AromaticContact CD2-CG 3.92Å; F307-F357 HydrophobicContact CD2-CG 3.92Å; F307-F357 HydrophobicContact CG-CD1 4.32Å; F307-F357 HydrophobicContact CG-CD2 4.5Å; F307-F357 HydrophobicContact CG-CG 4.3Å; F308-F357 HydrophobicContact CD2-CD2 4.18Å; F308-F357 AromaticContact CD2-CE2 3.71Å; F308-F357 HydrophobicContact CD2-CE2 3.71Å; F308-F357 HydrophobicContact CE2-CD2 4.08Å; F308-F357 AromaticContact CE2-CE2 3.85Å; F308-F357 HydrophobicContact CE2-CE2 3.85Å; F308-F357 HydrophobicContact CG-CE2 4.23Å; F308-F357 HydrophobicContact CZ-CE2 4.46Å; E311-F357 HydrophobicContact CB-CE1 4.48Å; E311-F357 HydrophobicContact CB-CZ 3.83Å; E311-F357 HydrophobicContact CG-CZ 4.16Å; T353-F357 VanDerWaalsContact O-CB 3.24Å; T353-F357 WeakPolarHBondContact O-CB 3.31Å; T353-F357 PolarHBondContact O-N 3.22Å; R355-F357 VanDerWaalsContact C-N 3.34Å; R355-F357 PolarHBondContact O-N 3.19Å; F357-Y360 PolarHBondContact O-N 3.48Å; F357-H361 AromaticContact CD1-ND1 3.76Å; F357-H361 AromaticContact CD2-CE1 3.56Å; F357-H361 AromaticContact CD2-ND1 3.79Å; F357-H361 AromaticContact CE1-CE1 3.87Å; F357-H361 AromaticContact CE1-ND1 3.61Å; F357-H361 AromaticContact CE2-CE1 3.14Å; F357-H361 WeakPolarHBondContact CE2-CE1 3.27Å; F357-H361 AromaticContact CE2-ND1 3.66Å; F357-H361 AromaticContact CE2-NE2 3.89Å; F357-H361 AromaticContact CG-ND1 3.84Å; F357-H361 AromaticContact CZ-CE1 3.3Å; F357-H361 WeakPolarHBondContact CZ-CE1 3.48Å; F357-H361 AromaticContact CZ-ND1 3.56Å; F357-H361 AromaticContact CZ-NE2 3.76Å; F357-H361 PolarHBondContact O-N 2.83Å; F357-H361 PolarHBondContact O-ND1 3.27Å
358	L	91.6	Very high	87.6	Confident	81 Å²	81	53.6 Å²	53.6	42%	0.424	26%	0.262	S	S	.	.	H	α-helix	trans	-62.6	-46.8	-179.9	-179.1	66.6	0	0	0	111.9	T354 R355 H361 T362	T354-L358 WeakPolarHBondContact O-CB 3.35Å; T354-L358 PolarHBondContact O-N 3.13Å; R355-L358 PolarHBondContact O-N 3.3Å; L358-H361 PolarHBondContact O-N 3.26Å; L358-T362 WeakPolarHBondContact O-CB 3.43Å; L358-T362 PolarHBondContact O-N 3.18Å; L358-T362 PolarHBondContact O-OG1 2.83Å
359	Y	89	Confident	86	Confident	118 Å²	118	56 Å²	56	46%	0.463	27%	0.268	S	S	.	.	H	α-helix	trans	-62.7	-44.5	179.1	-66.5	-19.9	0	0	0	111.4	R355 H361 T362 L363	R355-Y359 HydrophobicContact CB-CE2 4.2Å; R355-Y359 WeakPolarHBondContact O-CB 3.37Å; R355-Y359 WeakPolarHBondContact O-CD2 3.04Å; R355-Y359 PolarHBondContact O-N 3.26Å; Y359-H361 PolarHBondContact O-N 3.37Å; Y359-T362 PolarHBondContact O-N 3.05Å; Y359-L363 WeakPolarHBondContact O-CB 3.46Å; Y359-L363 WeakPolarHBondContact O-CG 2.92Å; Y359-L363 PolarHBondContact O-N 2.7Å
360	Y	89.3	Confident	84.4	Confident	17 Å²	17	57.4 Å²	57.4	7%	0.067	27%	0.274	C	S	.	.	H	α-helix	trans	-58.9	-50.2	177.1	-172.9	-80.7	0	0	0	111.9	R228 S231 L232 L356 F357 L363 A364 F382 E386	R228-Y360 HydrophobicContact CB-CE1 4.07Å; R228-Y360 HydrophobicContact CG-CE1 3.75Å; R228-Y360 WeakPolarHBondContact CG-OH 3.14Å; S231-Y360 PolarHBondContact OG-OH 2.99Å; L232-Y360 HydrophobicContact CD1-CD1 4.01Å; L232-Y360 HydrophobicContact CD1-CD2 4.34Å; L232-Y360 HydrophobicContact CD1-CG 3.91Å; L232-Y360 HydrophobicContact CD2-CD2 3.76Å; L232-Y360 HydrophobicContact CD2-CG 3.87Å; L232-Y360 HydrophobicContact CG-CD1 4.44Å; L232-Y360 HydrophobicContact CG-CD2 3.9Å; L232-Y360 HydrophobicContact CG-CE2 4.31Å; L232-Y360 HydrophobicContact CG-CG 3.98Å; L356-Y360 WeakPolarHBondContact O-CB 3.32Å; L356-Y360 PolarHBondContact O-N 2.96Å; F357-Y360 PolarHBondContact O-N 3.48Å; Y360-L363 PolarHBondContact O-N 2.75Å; Y360-A364 WeakPolarHBondContact O-CB 3.07Å; Y360-A364 PolarHBondContact O-N 3.42Å; Y360-F382 AromaticContact CD2-CD2 3.8Å; Y360-F382 HydrophobicContact CD2-CD2 3.8Å; Y360-F382 AromaticContact CE2-CD2 3.69Å; Y360-F382 HydrophobicContact CE2-CD2 3.69Å; Y360-F382 HydrophobicContact CE2-CE2 4.45Å; Y360-F382 HydrophobicContact CG-CD2 4.32Å; Y360-E386 PolarHBondContact OH-OE1 3.47Å
361	H	88.4	Confident	82.8	Confident	7 Å²	7	61.8 Å²	61.8	3%	0.032	30%	0.295	C	S	.	.	H	α-helix	trans	-72.9	-33	-177.5	-70.6	80.5	0	0	0	112.3	E311 Y312 F357 L358 Y359 A364 N365	E311-H361 IonicContact OE1-CD2 2.73Å; Y312-H361 AromaticContact CE2-NE2 3.78Å; Y312-H361 AromaticContact CZ-NE2 3.68Å; Y312-H361 PolarHBondContact OH-NE2 3.44Å; F357-H361 AromaticContact CD1-ND1 3.76Å; F357-H361 AromaticContact CD2-CE1 3.56Å; F357-H361 AromaticContact CD2-ND1 3.79Å; F357-H361 AromaticContact CE1-CE1 3.87Å; F357-H361 AromaticContact CE1-ND1 3.61Å; F357-H361 AromaticContact CE2-CE1 3.14Å; F357-H361 WeakPolarHBondContact CE2-CE1 3.27Å; F357-H361 AromaticContact CE2-ND1 3.66Å; F357-H361 AromaticContact CE2-NE2 3.89Å; F357-H361 AromaticContact CG-ND1 3.84Å; F357-H361 AromaticContact CZ-CE1 3.3Å; F357-H361 WeakPolarHBondContact CZ-CE1 3.48Å; F357-H361 AromaticContact CZ-ND1 3.56Å; F357-H361 AromaticContact CZ-NE2 3.76Å; F357-H361 PolarHBondContact O-N 2.83Å; F357-H361 PolarHBondContact O-ND1 3.27Å; L358-H361 PolarHBondContact O-N 3.26Å; Y359-H361 PolarHBondContact O-N 3.37Å; H361-A364 PolarHBondContact O-N 3.37Å; H361-N365 WeakPolarHBondContact O-CB 3.05Å; H361-N365 PolarHBondContact O-N 2.86Å; H361-N365 PolarHBondContact O-ND2 3.47Å
362	T	85.9	Confident	81.5	Confident	66 Å²	66	58.2 Å²	58.2	41%	0.405	29%	0.287	S	S	.	.	H	α-helix	trans	-62.7	-44.2	173	-58.3	0	0	0	0	111	L358 Y359 T366	L358-T362 WeakPolarHBondContact O-CB 3.43Å; L358-T362 PolarHBondContact O-N 3.18Å; L358-T362 PolarHBondContact O-OG1 2.83Å; Y359-T362 PolarHBondContact O-N 3.05Å; T362-T366 VanDerWaalsContact O-CB 3.24Å; T362-T366 WeakPolarHBondContact O-CB 3.13Å; T362-T366 PolarHBondContact O-N 3.24Å; T362-T366 VanDerWaalsContact O-N 3.11Å; T362-T366 PolarHBondContact O-OG1 2.93Å
363	L	83.1	Confident	80.2	Confident	22 Å²	22	66.3 Å²	66.3	12%	0.115	32%	0.315	C	S	.	.	H	α-helix	trans	-67.1	-41.8	175.9	-69.1	170.1	0	0	0	111.6	Y359 Y360 Y369 Q370 F379 F382	Y359-L363 WeakPolarHBondContact O-CB 3.46Å; Y359-L363 WeakPolarHBondContact O-CG 2.92Å; Y359-L363 PolarHBondContact O-N 2.7Å; Y360-L363 PolarHBondContact O-N 2.75Å; L363-Y369 HydrophobicContact CD2-CG 4.18Å; L363-Q370 VanDerWaalsContact O-CG 3.26Å; L363-Q370 WeakPolarHBondContact O-CG 3.42Å; L363-F379 HydrophobicContact CD1-CD2 3.85Å; L363-F379 HydrophobicContact CD1-CE2 4.05Å; L363-F379 HydrophobicContact CD1-CG 4.26Å; L363-F382 VanDerWaalsContact C-CZ 3.44Å; L363-F382 HydrophobicContact CB-CD1 4.43Å; L363-F382 HydrophobicContact CB-CD2 4.47Å; L363-F382 HydrophobicContact CB-CE1 3.73Å; L363-F382 HydrophobicContact CB-CE2 3.77Å; L363-F382 HydrophobicContact CB-CZ 3.37Å; L363-F382 HydrophobicContact CD1-CD1 4.45Å; L363-F382 HydrophobicContact CD1-CE1 4.49Å
364	A	81.8	Confident	79.2	Confident	0 Å²	0	74.6 Å²	74.6	0%	0	35%	0.347	C	S	.	.	H	α-helix	trans	-66.5	-36.5	179	0	0	0	0	0	112.6	Y360 H361 Q370 F382	Y360-A364 WeakPolarHBondContact O-CB 3.07Å; Y360-A364 PolarHBondContact O-N 3.42Å; H361-A364 PolarHBondContact O-N 3.37Å; A364-Q370 PolarHBondContact O-NE2 2.86Å; A364-F382 HydrophobicContact CB-CE2 4.02Å; A364-F382 HydrophobicContact CB-CZ 4.37Å
365	N	81.1	Confident	77.9	Confident	54 Å²	54	73.5 Å²	73.5	29%	0.289	34%	0.341	S	S	.	.	H	α-helix	trans	-85.3	-19.1	-176	-66.5	-18.4	0	0	0	112.6	H361 P392	H361-N365 WeakPolarHBondContact O-CB 3.05Å; H361-N365 PolarHBondContact O-N 2.86Å; H361-N365 PolarHBondContact O-ND2 3.47Å; N365-P392 WeakPolarHBondContact OD1-CA 3.31Å
366	T	78.4	Confident	76.7	Confident	51 Å²	51	75.7 Å²	75.7	31%	0.313	35%	0.35	S	S	.	.			trans	-106.6	105.4	-176.3	-48.4	0	0	0	0	112.4	T362 A368 Y369 Q370	T362-T366 VanDerWaalsContact O-CB 3.24Å; T362-T366 WeakPolarHBondContact O-CB 3.13Å; T362-T366 PolarHBondContact O-N 3.24Å; T362-T366 VanDerWaalsContact O-N 3.11Å; T362-T366 PolarHBondContact O-OG1 2.93Å; T366-A368 VanDerWaalsContact C-N 3.29Å; T366-A368 HydrophobicContact CG2-CB 4.39Å; T366-A368 PolarHBondContact O-N 3.41Å; T366-Y369 HydrophobicContact CG2-CD2 3.59Å; T366-Y369 HydrophobicContact CG2-CE2 4.11Å; T366-Y369 PolarHBondContact O-N 3.37Å; T366-Y369 VanDerWaalsContact O-N 3.11Å; T366-Q370 PolarHBondContact O-N 2.99Å
367	R	64.9	Low	75.7	Confident	144 Å²	144	79.3 Å²	79.3	54%	0.543	37%	0.368	S	S	.	.	H	α-helix	trans	-56.5	-36.1	-177.4	-67.6	-173.5	176.6	176.5	1.1	114.6	Y369 Q370 N390	R367-Y369 PolarHBondContact O-N 3.36Å; R367-Q370 PolarHBondContact O-N 3.32Å; R367-N390 PolarHBondContact NH2-O 2.73Å
368	A	60.8	Low	74.6	Confident	80 Å²	80	86.6 Å²	86.6	66%	0.661	40%	0.395	S	S	*	.	H	α-helix	trans	-61.3	-31.3	-179.5	0	0	0	0	0	112.9	T366	T366-A368 VanDerWaalsContact C-N 3.29Å; T366-A368 HydrophobicContact CG2-CB 4.39Å; T366-A368 PolarHBondContact O-N 3.41Å
369	Y	60.2	Low	73.8	Confident	122 Å²	122	86.5 Å²	86.5	48%	0.478	39%	0.391	S	S	.	.	H	α-helix	trans	-88.1	-27.6	179.7	-70.8	-72.6	0	0	0	113.2	L363 T366 R367 Q371 S372 A375	L363-Y369 HydrophobicContact CD2-CG 4.18Å; T366-Y369 HydrophobicContact CG2-CD2 3.59Å; T366-Y369 HydrophobicContact CG2-CE2 4.11Å; T366-Y369 PolarHBondContact O-N 3.37Å; T366-Y369 VanDerWaalsContact O-N 3.11Å; R367-Y369 PolarHBondContact O-N 3.36Å; Y369-Q371 PolarHBondContact O-N 3.15Å; Y369-S372 WeakPolarHBondContact O-CB 3.26Å; Y369-S372 PolarHBondContact O-N 2.84Å; Y369-A375 WeakPolarHBondContact O-CB 3.41Å
370	Q	60	Low	72.9	Confident	29 Å²	29	84.8 Å²	84.8	14%	0.136	39%	0.394	C	S	.	.	H	α-helix	trans	-60.8	-33.2	176.8	-67.8	-172.5	-50.3	0	0	112.7	L363 A364 T366 R367 F382 V389	L363-Q370 VanDerWaalsContact O-CG 3.26Å; L363-Q370 WeakPolarHBondContact O-CG 3.42Å; A364-Q370 PolarHBondContact O-NE2 2.86Å; T366-Q370 PolarHBondContact O-N 2.99Å; R367-Q370 PolarHBondContact O-N 3.32Å; Q370-F382 HydrophobicContact CG-CZ 4.49Å; Q370-V389 PolarHBondContact NE2-O 2.87Å
371	Q	62.6	Low	72	Confident	161 Å²	161	87.1 Å²	87.1	75%	0.752	41%	0.407	S	S	*	.	T	Hydrogen-bonded Turn	trans	-92	-2.8	179.9	-67.3	-178.4	-14.6	0	0	113.7	Y369 R373	Y369-Q371 PolarHBondContact O-N 3.15Å; Q371-R373 PolarHBondContact O-N 2.98Å
372	S	68.5	Low	71.3	Confident	41 Å²	41	87.4 Å²	87.4	29%	0.287	41%	0.408	S	S	.	.			trans	-72.5	128.2	-178.7	-176.9	0	0	0	0	111.8	Y369 R374 A375 R376	Y369-S372 WeakPolarHBondContact O-CB 3.26Å; Y369-S372 PolarHBondContact O-N 2.84Å; S372-R374 PolarHBondContact O-N 3.21Å; S372-R374 PolarHBondContact OG-N 3.39Å; S372-A375 PolarHBondContact O-N 3.16Å; S372-A375 VanDerWaalsContact O-N 3.14Å; S372-R376 PolarHBondContact O-N 2.01Å
373	R	67.5	Low	70.4	Confident	209 Å²	209	84.9 Å²	84.9	79%	0.789	39%	0.393	S	S	*	.	H	α-helix	trans	-55.6	-33.3	172.4	-168.5	178.7	-179.1	-168.1	1.5	111.9	Q371 R376 I377	Q371-R373 PolarHBondContact O-N 2.98Å; R373-R376 PolarHBondContact O-N 3.14Å; R373-I377 HydrophobicContact CG-CD1 4.28Å; R373-I377 WeakPolarHBondContact O-CG1 3.43Å; R373-I377 PolarHBondContact O-N 3.36Å
374	R	73.3	Confident	70	Confident	175 Å²	175	87.8 Å²	87.8	66%	0.66	41%	0.405	S	S	*	.	H	α-helix	trans	-68.3	-45.4	177.6	-166.8	174.9	-172.1	163.8	2.7	111.6	S372 R376 I377 W378	S372-R374 PolarHBondContact O-N 3.21Å; S372-R374 PolarHBondContact OG-N 3.39Å; R374-R376 PolarHBondContact O-N 2.9Å; R374-I377 PolarHBondContact O-N 2.81Å; R374-I377 VanDerWaalsContact O-N 3.15Å; R374-W378 PolarHBondContact O-N 2.97Å
375	A	68.1	Low	69.7	Low	11 Å²	11	87.9 Å²	87.9	9%	0.091	41%	0.405	C	S	.	.	H	α-helix	trans	-60.4	-36.3	177.1	0	0	0	0	0	111.9	Y369 S372 F379	Y369-A375 WeakPolarHBondContact O-CB 3.41Å; S372-A375 PolarHBondContact O-N 3.16Å; S372-A375 VanDerWaalsContact O-N 3.14Å; A375-F379 WeakPolarHBondContact O-CA 3.2Å; A375-F379 WeakPolarHBondContact O-CB 3.24Å; A375-F379 PolarHBondContact O-N 3.31Å
376	R	69	Low	69.4	Low	140 Å²	140	85.5 Å²	85.5	53%	0.528	39%	0.392	S	S	.	.	H	α-helix	trans	-65.9	-35.4	176	-171.3	176.8	-59.5	164.4	5	113.8	S372 R373 R374 P380 S383	S372-R376 PolarHBondContact O-N 2.01Å; R373-R376 PolarHBondContact O-N 3.14Å; R374-R376 PolarHBondContact O-N 2.9Å; R376-P380 WeakPolarHBondContact O-CA 3.48Å; R376-S383 WeakPolarHBondContact CG-OG 3.29Å
377	I	73.1	Confident	68.7	Low	117 Å²	117	86.3 Å²	86.3	60%	0.6	40%	0.399	S	S	*	.	H	α-helix	trans	-76.3	-44.8	179	-67.5	165.3	0	0	0	111	R373 R374	R373-I377 HydrophobicContact CG-CD1 4.28Å; R373-I377 WeakPolarHBondContact O-CG1 3.43Å; R373-I377 PolarHBondContact O-N 3.36Å; R374-I377 PolarHBondContact O-N 2.81Å; R374-I377 VanDerWaalsContact O-N 3.15Å
378	W	70.8	Confident	68.5	Low	174 Å²	174	83.8 Å²	83.8	66%	0.659	40%	0.396	S	S	*	.	H	α-helix	trans	-79.2	-27.2	-176.2	-72.7	77	0	0	0	112.8	R374	R374-W378 PolarHBondContact O-N 2.97Å
379	F	74	Confident	68.7	Low	78 Å²	78	80.2 Å²	80.2	34%	0.342	37%	0.366	S	S	.	.			trans	-133	70	179	-56.5	-83.8	0	0	0	111.2	L363 A375 M381 F382 S383	L363-F379 HydrophobicContact CD1-CD2 3.85Å; L363-F379 HydrophobicContact CD1-CE2 4.05Å; L363-F379 HydrophobicContact CD1-CG 4.26Å; A375-F379 WeakPolarHBondContact O-CA 3.2Å; A375-F379 WeakPolarHBondContact O-CB 3.24Å; A375-F379 PolarHBondContact O-N 3.31Å; F379-M381 PolarHBondContact O-N 3.07Å; F379-F382 HydrophobicContact CB-CB 3.68Å; F379-F382 HydrophobicContact CB-CD1 4.49Å; F379-F382 HydrophobicContact CB-CG 4.4Å; F379-F382 WeakPolarHBondContact O-CB 3.47Å; F379-F382 PolarHBondContact O-N 3.35Å; F379-S383 PolarHBondContact O-N 2.91Å
380	P	69.8	Low	68.8	Low	82 Å²	82	77.6 Å²	77.6	53%	0.532	36%	0.361	S	S	.	.	H	α-helix	trans	-63.6	-40.7	-175.7	23.9	-33	0	0	0	112.6	R376 F382 S383 F384	R376-P380 WeakPolarHBondContact O-CA 3.48Å; P380-F382 PolarHBondContact O-N 2.96Å; P380-S383 PolarHBondContact O-N 3.42Å; P380-F384 PolarHBondContact O-N 2.83Å
381	M	70.1	Confident	69.1	Low	67 Å²	67	76.3 Å²	76.3	33%	0.33	36%	0.356	S	S	.	.	H	α-helix	trans	-62.7	-41.8	175.9	-75.8	-71.2	-88.4	0	0	112.2	Y155 F379 F384 F385	Y155-M381 HydrophobicContact CD1-CE 3.74Å; Y155-M381 HydrophobicContact CD2-CE 4.1Å; Y155-M381 HydrophobicContact CE1-CE 3.68Å; Y155-M381 HydrophobicContact CE2-CE 4.07Å; Y155-M381 HydrophobicContact CG-CE 3.94Å; F379-M381 PolarHBondContact O-N 3.07Å; M381-F384 PolarHBondContact O-N 2.94Å; M381-F385 HydrophobicContact CE-CE2 3.61Å; M381-F385 HydrophobicContact CE-CZ 4.24Å; M381-F385 WeakPolarHBondContact O-CD2 3.37Å; M381-F385 PolarHBondContact O-N 3.14Å; M381-F385 VanDerWaalsContact O-N 3.11Å; M381-F385 HydrophobicContact SD-CE2 4.07Å
382	F	75.4	Confident	69.6	Low	13 Å²	13	73.2 Å²	73.2	6%	0.057	35%	0.349	C	S	.	.	H	α-helix	trans	-61.4	-50.1	174.9	169.3	-93.8	0	0	0	110.9	Y360 L363 A364 Q370 F379 P380 F384 F385 E386	Y360-F382 AromaticContact CD2-CD2 3.8Å; Y360-F382 HydrophobicContact CD2-CD2 3.8Å; Y360-F382 AromaticContact CE2-CD2 3.69Å; Y360-F382 HydrophobicContact CE2-CD2 3.69Å; Y360-F382 HydrophobicContact CE2-CE2 4.45Å; Y360-F382 HydrophobicContact CG-CD2 4.32Å; L363-F382 VanDerWaalsContact C-CZ 3.44Å; L363-F382 HydrophobicContact CB-CD1 4.43Å; L363-F382 HydrophobicContact CB-CD2 4.47Å; L363-F382 HydrophobicContact CB-CE1 3.73Å; L363-F382 HydrophobicContact CB-CE2 3.77Å; L363-F382 HydrophobicContact CB-CZ 3.37Å; L363-F382 HydrophobicContact CD1-CD1 4.45Å; L363-F382 HydrophobicContact CD1-CE1 4.49Å; A364-F382 HydrophobicContact CB-CE2 4.02Å; A364-F382 HydrophobicContact CB-CZ 4.37Å; Q370-F382 HydrophobicContact CG-CZ 4.49Å; F379-F382 HydrophobicContact CB-CB 3.68Å; F379-F382 HydrophobicContact CB-CD1 4.49Å; F379-F382 HydrophobicContact CB-CG 4.4Å; F379-F382 WeakPolarHBondContact O-CB 3.47Å; F379-F382 PolarHBondContact O-N 3.35Å; P380-F382 PolarHBondContact O-N 2.96Å; F382-F384 VanDerWaalsContact C-N 3.3Å; F382-F384 PolarHBondContact O-N 2.98Å; F382-F385 PolarHBondContact O-N 3.4Å; F382-E386 HydrophobicContact CD2-CB 4.5Å; F382-E386 HydrophobicContact CD2-CG 4.08Å; F382-E386 HydrophobicContact CE2-CB 4.1Å; F382-E386 HydrophobicContact CE2-CG 3.8Å; F382-E386 HydrophobicContact CZ-CB 4.13Å; F382-E386 HydrophobicContact CZ-CG 4.33Å; F382-E386 WeakPolarHBondContact O-CB 3.09Å; F382-E386 PolarHBondContact O-N 3.35Å
383	S	65.1	Low	70	Confident	12 Å²	12	71.9 Å²	71.9	8%	0.084	34%	0.34	C	S	.	.	H	α-helix	trans	-57.7	-46.2	-179.6	-173.6	0	0	0	0	110.7	R376 F379 P380 C387	R376-S383 WeakPolarHBondContact CG-OG 3.29Å; F379-S383 PolarHBondContact O-N 2.91Å; P380-S383 PolarHBondContact O-N 3.42Å; S383-C387 WeakPolarHBondContact O-CB 3.23Å; S383-C387 PolarHBondContact O-N 3.38Å; S383-C387 PolarHBondContact O-SG 3.47Å
384	F	75.7	Confident	70.5	Confident	83 Å²	83	64.4 Å²	64.4	36%	0.364	32%	0.318	S	S	.	.	H	α-helix	trans	-62.8	-46.2	-178.9	175.5	-96.5	0	0	0	113.2	W147 L151 P380 M381 F382	W147-F384 HydrophobicContact CH2-CE1 4.47Å; W147-F384 HydrophobicContact CH2-CE2 4.09Å; W147-F384 AromaticContact CH2-CZ 3.47Å; W147-F384 HydrophobicContact CH2-CZ 3.47Å; W147-F384 VanDerWaalsContact CH2-CZ 3.47Å; W147-F384 HydrophobicContact CZ2-CZ 4.16Å; W147-F384 HydrophobicContact CZ3-CZ 4.07Å; L151-F384 HydrophobicContact CD2-CE1 3.64Å; L151-F384 HydrophobicContact CD2-CZ 3.8Å; P380-F384 PolarHBondContact O-N 2.83Å; M381-F384 PolarHBondContact O-N 2.94Å; F382-F384 VanDerWaalsContact C-N 3.3Å; F382-F384 PolarHBondContact O-N 2.98Å
385	F	74.7	Confident	70.7	Confident	3 Å²	3	58.9 Å²	58.9	1%	0.013	30%	0.302	C	S	.	.	H	α-helix	trans	-74.2	-35.1	-178	-71.6	-53.4	0	0	0	113.1	K148 R227 M381 F382	K148-F385 HydrophobicContact CB-CD1 4.3Å; K148-F385 WeakPolarHBondContact O-CE1 3.49Å; R227-F385 HydrophobicContact CG-CB 4.35Å; R227-F385 HydrophobicContact CG-CD1 3.92Å; R227-F385 HydrophobicContact CG-CE1 4.5Å; R227-F385 HydrophobicContact CG-CG 4.2Å; R227-F385 PolarHBondContact NE-O 2.85Å; R227-F385 PolarHBondContact NH1-O 2.99Å; R227-F385 VanDerWaalsContact NH1-O 3.12Å; R227-F385 PolarHBondContact NH2-O 2.75Å; M381-F385 HydrophobicContact CE-CE2 3.61Å; M381-F385 HydrophobicContact CE-CZ 4.24Å; M381-F385 WeakPolarHBondContact O-CD2 3.37Å; M381-F385 PolarHBondContact O-N 3.14Å; M381-F385 VanDerWaalsContact O-N 3.11Å; M381-F385 HydrophobicContact SD-CE2 4.07Å; F382-F385 PolarHBondContact O-N 3.4Å
386	E	75.6	Confident	71.2	Confident	3 Å²	3	61.8 Å²	61.8	1%	0.014	31%	0.313	C	S	.	.	H	α-helix	trans	-98.6	-0.1	-173.7	-66.2	-67.4	120.5	0	0	114.4	R227 R228 Y360 F382 N388 V389	R227-E386 IonicContact CZ-OE1 3.75Å; R227-E386 IonicContact NE-OE1 2.69Å; R227-E386 IonicContact NH2-OE1 3.64Å; R227-E386 PolarHBondContact NH2-OE1 3.42Å; R228-E386 IonicContact CZ-OE2 2.99Å; R228-E386 IonicContact NE-OE1 3.28Å; R228-E386 PolarHBondContact NE-OE1 3.41Å; R228-E386 IonicContact NE-OE2 3.55Å; R228-E386 PolarHBondContact NE-OE2 3.18Å; R228-E386 IonicContact NH2-OE2 3.71Å; R228-E386 PolarHBondContact NH2-OE2 3.34Å; Y360-E386 PolarHBondContact OH-OE1 3.47Å; F382-E386 HydrophobicContact CD2-CB 4.5Å; F382-E386 HydrophobicContact CD2-CG 4.08Å; F382-E386 HydrophobicContact CE2-CB 4.1Å; F382-E386 HydrophobicContact CE2-CG 3.8Å; F382-E386 HydrophobicContact CZ-CB 4.13Å; F382-E386 HydrophobicContact CZ-CG 4.33Å; F382-E386 WeakPolarHBondContact O-CB 3.09Å; F382-E386 PolarHBondContact O-N 3.35Å; E386-N388 PolarHBondContact O-N 3.16Å; E386-V389 PolarHBondContact O-N 3.42Å; E386-V389 WeakPolarHBondContact OE2-CB 3.45Å; E386-V389 WeakPolarHBondContact OE2-CG1 3.45Å
387	C	62.7	Low	71.7	Confident	69 Å²	69	58.2 Å²	58.2	47%	0.466	30%	0.3	S	S	.	.	T	Hydrogen-bonded Turn	trans	-45.8	-33.9	178.1	-92.9	0	0	0	0	114.9	S383	S383-C387 WeakPolarHBondContact O-CB 3.23Å; S383-C387 PolarHBondContact O-N 3.38Å; S383-C387 PolarHBondContact O-SG 3.47Å
388	N	61.5	Low	71.7	Confident	90 Å²	90	54.4 Å²	54.4	48%	0.481	29%	0.29	S	S	.	.	T	Hydrogen-bonded Turn	trans	-107.8	1.5	-174.3	-65.1	-14.8	0	0	0	113.5	E145 K148 E386	E145-N388 PolarHBondContact OE1-ND2 3.47Å; K148-N388 PolarHBondContact NZ-ND2 3.38Å; E386-N388 PolarHBondContact O-N 3.16Å
389	V	65.7	Low	71.8	Confident	5 Å²	5	53.1 Å²	53.1	3%	0.03	29%	0.285	C	S	.	.			trans	-104.5	102.8	178.2	174.4	0	0	0	0	109.5	L142 V224 Q370 E386 G391 V393	L142-V389 HydrophobicContact CD2-CB 4.15Å; L142-V389 HydrophobicContact CD2-CG1 3.74Å; L142-V389 HydrophobicContact CD2-CG2 3.96Å; V224-V389 HydrophobicContact CG1-CG2 4.24Å; V224-V389 HydrophobicContact CG2-CG2 4.38Å; Q370-V389 PolarHBondContact NE2-O 2.87Å; E386-V389 PolarHBondContact O-N 3.42Å; E386-V389 WeakPolarHBondContact OE2-CB 3.45Å; E386-V389 WeakPolarHBondContact OE2-CG1 3.45Å; V389-G391 PolarHBondContact O-N 3.07Å; V389-V393 HydrophobicContact CG1-CG2 4.43Å
390	N	61.4	Low	71.4	Confident	67 Å²	67	51.4 Å²	51.4	36%	0.358	28%	0.282	S	S	.	.			trans	-96.5	76.4	-171	-73.7	-61.7	0	0	0	112.7	R367	R367-N390 PolarHBondContact NH2-O 2.73Å
391	G	66.3	Low	71.2	Confident	3 Å²	3	54.5 Å²	54.5	3%	0.031	29%	0.287	C	S	.	.	S	Bend	trans	107.3	-166.3	173.2	0	0	0	0	0	114.8	V389	V389-G391 PolarHBondContact O-N 3.07Å
392	P	72.9	Confident	70.6	Confident	95 Å²	95	57 Å²	57	62%	0.617	31%	0.311	S	S	*	.	P	Polyproline II helix	trans	-65.8	137.4	-175.1	26.6	-33.8	0	0	0	111.5	N365	N365-P392 WeakPolarHBondContact OD1-CA 3.31Å
393	V	77.6	Confident	69.6	Low	14 Å²	14	64.4 Å²	64.4	9%	0.085	34%	0.343	C	S	.	.	P	Polyproline II helix	trans	-76.7	126.1	176.6	178.2	0	0	0	0	108	L142 H221 V224 L225 Y312 V389	L142-V393 HydrophobicContact CD1-CG1 4.34Å; L142-V393 HydrophobicContact CD1-CG2 4.35Å; H221-V393 HydrophobicContact CB-CG1 3.9Å; V224-V393 HydrophobicContact CG1-CG2 3.99Å; L225-V393 HydrophobicContact CD1-CG1 4.04Å; Y312-V393 HydrophobicContact CE1-CB 4.41Å; V389-V393 HydrophobicContact CG1-CG2 4.43Å
394	P	77.8	Confident	69.2	Low	51 Å²	51	66 Å²	66	33%	0.331	35%	0.354	S	S	.	.	P	Polyproline II helix	trans	-71.2	139.4	177.7	30.4	-34.3	0	0	0	110.3	H219 E396	H219-P394 PolarHBondContact CE1-O 2.83Å; H219-P394 PolarHBondContact NE2-O 3.02Å; P394-E396 HydrophobicContact CB-CG 4.2Å; P394-E396 HydrophobicContact CG-CG 4.4Å; P394-E396 PolarHBondContact O-N 3.48Å
395	N	76.7	Confident	68.3	Low	60 Å²	60	66 Å²	66	32%	0.321	37%	0.368	S	S	.	.			trans	-77.6	69	177.7	-68.1	-7.3	0	0	0	110.1	E311 T313 Y397	E311-N395 PolarHBondContact O-ND2 3.3Å; T313-N395 PolarHBondContact O-ND2 2.99Å; N395-Y397 HydrophobicContact CB-CE2 4.41Å
396	E	79.1	Confident	67.3	Low	71 Å²	71	73.2 Å²	73.2	33%	0.332	40%	0.404	S	S	.	.			trans	-99.2	124.5	177.8	-72.1	-179	-161.5	0	0	110.9	K220 P394	K220-E396 HydrophobicContact CB-CB 4.21Å; K220-E396 VanDerWaalsContact CB-O 3.31Å; K220-E396 WeakPolarHBondContact CB-O 3.49Å; K220-E396 HydrophobicContact CD-CB 4.11Å; K220-E396 VanDerWaalsContact CD-OE2 3.26Å; K220-E396 WeakPolarHBondContact CD-OE2 3.05Å; K220-E396 PolarHBondContact N-O 3.36Å; K220-E396 IonicContact NZ-OE2 3.36Å; K220-E396 PolarHBondContact NZ-OE2 3.17Å; P394-E396 HydrophobicContact CB-CG 4.2Å; P394-E396 HydrophobicContact CG-CG 4.4Å; P394-E396 PolarHBondContact O-N 3.48Å
397	Y	78.9	Confident	66.3	Low	65 Å²	65	77.2 Å²	77.2	26%	0.255	43%	0.425	S	S	.	.	B	Isolated β-bridge	trans	-106	138.4	179.9	-71.2	-93.7	0	0	0	111.1	V215 L218 Y312 T313 P314 W317 N395	V215-Y397 HydrophobicContact CG1-CE1 4.38Å; L218-Y397 HydrophobicContact CB-CD1 3.73Å; L218-Y397 HydrophobicContact CB-CE1 4.27Å; L218-Y397 CarbonylContact O-C 3.51Å; L218-Y397 VanDerWaalsContact O-CA 3.28Å; L218-Y397 WeakPolarHBondContact O-CA 3.05Å; L218-Y397 WeakPolarHBondContact O-CD1 3.46Å; Y312-Y397 PolarHBondContact O-OH 3.21Å; T313-Y397 VanDerWaalsContact CA-OH 3.25Å; T313-Y397 WeakPolarHBondContact CA-OH 3.46Å; T313-Y397 WeakPolarHBondContact CG2-OH 3.48Å; P314-Y397 HydrophobicContact CG-CD2 4.13Å; P314-Y397 HydrophobicContact CG-CE2 3.56Å; W317-Y397 HydrophobicContact CH2-CE1 4.32Å; W317-Y397 HydrophobicContact CZ3-CE1 4.35Å; N395-Y397 HydrophobicContact CB-CE2 4.41Å
398	G	73.9	Confident	65.8	Low	37 Å²	37	82.3 Å²	82.3	38%	0.381	43%	0.434	S	S	.	.			trans	-146.5	144.7	177.7	0	0	0	0	0	110.8	L218	L218-G398 CarbonylContact C-O 3.52Å; L218-G398 PolarHBondContact O-N 3.01Å
399	W	72.4	Confident	65.4	Low	147 Å²	147	89 Å²	89	56%	0.557	45%	0.453	S	S	*	.			trans	-68	126.7	176.9	-164.2	-112	0	0	0	109.8	L218 F401	L218-W399 HydrophobicContact CD2-CE3 3.68Å; L218-W399 HydrophobicContact CD2-CZ3 3.68Å; W399-F401 VanDerWaalsContact C-N 3.3Å; W399-F401 PolarHBondContact O-N 3.22Å
400	P	66.6	Low	64.5	Low	42 Å²	42	96.9 Å²	96.9	27%	0.273	49%	0.491	S	S	.	.	S	Bend	trans	-74.8	-18.2	-172.6	26.9	-34.2	0	0	0	113.9	L217	L217-P400 WeakPolarHBondContact O-CG 3.44Å
401	F	66.1	Low	64	Low	148 Å²	148	99.5 Å²	99.5	65%	0.649	50%	0.504	S	S	*	.	S	Bend	trans	-101	152.9	177.5	-58	-74.9	0	0	0	110.2	W399 K403	W399-F401 VanDerWaalsContact C-N 3.3Å; W399-F401 PolarHBondContact O-N 3.22Å; F401-K403 PolarHBondContact O-N 3.07Å
402	S	56.5	Low	62.9	Low	120 Å²	120	102.5 Å²	102.5	84%	0.839	54%	0.535	S	S	*	.	S	Bend	trans	-50.7	121.5	166	-59.4	0	0	0	0	107.7
403	K	54.7	Low	61.4	Low	168 Å²	168	111 Å²	111	73%	0.73	56%	0.556	S	S	*	*			trans	-32.4	116.8	-173	-65	-178.8	-179.8	-176	0	109.8	F401 A405	F401-K403 PolarHBondContact O-N 3.07Å; K403-A405 PolarHBondContact O-N 3.34Å
404	P	56.7	Low	60.6	Low	46 Å²	46	115.9 Å²	115.9	30%	0.299	58%	0.58	S	S	.	*			trans	-57.1	125.3	-178.5	20.4	-29.7	0	0	0	107	M406 I407	P404-M406 PolarHBondContact O-N 3.01Å; P404-I407 HydrophobicContact CG-CB 4.5Å; P404-I407 HydrophobicContact CG-CD1 3.73Å; P404-I407 HydrophobicContact CG-CG1 3.97Å; P404-I407 PolarHBondContact O-N 3Å
405	A	56	Low	59.7	Low	81 Å²	81	119.3 Å²	119.3	67%	0.669	59%	0.593	S	S	*	*	H	α-helix	trans	-53	-21.5	179.4	0	0	0	0	0	112	K403 I407 R408 R409	K403-A405 PolarHBondContact O-N 3.34Å; A405-I407 PolarHBondContact O-N 3.27Å; A405-R408 PolarHBondContact O-N 3.22Å; A405-R409 PolarHBondContact O-N 3.19Å
406	M	55	Low	58.8	Low	155 Å²	155	122.6 Å²	122.6	76%	0.764	61%	0.608	S	S	*	*	H	α-helix	trans	-60.1	-35.7	170.9	-79.2	-141.6	-84.7	0	0	114.8	P404 R409 M410	P404-M406 PolarHBondContact O-N 3.01Å; M406-R409 PolarHBondContact O-N 2.65Å; M406-M410 PolarHBondContact O-N 2.96Å; M406-M410 VanDerWaalsContact O-N 3.09Å
407	I	54.4	Low	57.6	Low	87 Å²	87	125.6 Å²	125.6	45%	0.446	62%	0.624	S	S	.	*	H	α-helix	trans	-76.9	-30.1	178.8	-66.7	177.1	0	0	0	111.3	P404 A405 R409 M410 I411	P404-I407 HydrophobicContact CG-CB 4.5Å; P404-I407 HydrophobicContact CG-CD1 3.73Å; P404-I407 HydrophobicContact CG-CG1 3.97Å; P404-I407 PolarHBondContact O-N 3Å; A405-I407 PolarHBondContact O-N 3.27Å; I407-R409 VanDerWaalsContact C-N 3.26Å; I407-R409 PolarHBondContact O-N 3.2Å; I407-M410 PolarHBondContact O-N 3.06Å; I407-I411 HydrophobicContact CG2-CD1 3.68Å; I407-I411 HydrophobicContact CG2-CG1 4.3Å; I407-I411 PolarHBondContact O-N 3.24Å; I407-I411 VanDerWaalsContact O-N 3.07Å
408	R	51.8	Low	56.2	Low	177 Å²	177	129.4 Å²	129.4	67%	0.668	65%	0.648	S	S	*	*	H	α-helix	trans	-60.9	-38.3	167.9	-90.5	-173.2	177.6	177.7	-1	111.4	A405 G412	A405-R408 PolarHBondContact O-N 3.22Å; R408-G412 PolarHBondContact O-N 3.14Å
409	R	52.7	Low	55.1	Low	231 Å²	231	135.5 Å²	135.5	87%	0.872	67%	0.665	S	S	*	*	H	α-helix	trans	-73.2	-28.6	178.8	-117.2	178.2	-178.5	170.4	0.2	114.1	A405 M406 I407	A405-R409 PolarHBondContact O-N 3.19Å; M406-R409 PolarHBondContact O-N 2.65Å; I407-R409 VanDerWaalsContact C-N 3.26Å; I407-R409 PolarHBondContact O-N 3.2Å
410	M	46.6	Very low	53.8	Low	170 Å²	170	134.7 Å²	134.7	84%	0.837	67%	0.673	S	S	*	*	H	α-helix	trans	-89.5	-21.5	178.7	-74.9	-165	79.2	0	0	114.7	M406 I407	M406-M410 PolarHBondContact O-N 2.96Å; M406-M410 VanDerWaalsContact O-N 3.09Å; I407-M410 PolarHBondContact O-N 3.06Å
411	I	52	Low	52.8	Low	122 Å²	122	141.8 Å²	141.8	63%	0.626	70%	0.704	S	S	*	*	H	α-helix	trans	-107	1.9	-176.2	-62.8	179.7	0	0	0	113.1	I407	I407-I411 HydrophobicContact CG2-CD1 3.68Å; I407-I411 HydrophobicContact CG2-CG1 4.3Å; I407-I411 PolarHBondContact O-N 3.24Å; I407-I411 VanDerWaalsContact O-N 3.07Å
412	G	42.4	Very low	51.7	Low	66 Å²	66	141.3 Å²	141.3	68%	0.68	71%	0.708	S	S	*	*	T	Hydrogen-bonded Turn	trans	62.8	68.4	168.3	0	0	0	0	0	113.3	R408	R408-G412 PolarHBondContact O-N 3.14Å
413	Y	42	Very low	51.3	Low	273 Å²	273	143.3 Å²	143.3	100%	1.071	70%	0.697	S	S	*	*			trans	-116.6	0	155.9	-89.4	-76.1	0	0	0	109.8

Retrieved 413 of 413 residues in 1882.6 ms (Link to these results)

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