A0A060YK66_ONCMY Loading...

Programmed cell death 2

AlphaFold DB , UniProt , Accession A0A060YK66, Species ONCMY (Oncorhynchus mykiss, Rainbow trout), Gene n/a, Length 347 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M30.6Very low76.5Confident224 Ų22469.6 Ų69.6100%1.10341%0.406SS*.  0117.50-71.7178.8-114.900105.2E3M1-E3 PolarHBondContact O-N 2.88Å
2A38Very low78.2Confident87 Ų8771.8 Ų71.872%0.71941%0.41SS*.  trans-65.2131.4175.400000107.5T4A2-T4 WeakPolarHBondContact O-CG2 3.42Å; A2-T4 PolarHBondContact O-N 3.39Å
3E50.3Low79.5Confident173 Ų17380.5 Ų80.581%0.80844%0.444SS*.  trans-59.4108.1169.4-74.9171163.900107.3M1 G5M1-E3 PolarHBondContact O-N 2.88Å; E3-G5 PolarHBondContact O-N 2.87Å; E3-G5 VanDerWaalsContact O-N 3.08Å
4T62.3Low80.3Confident139 Ų13976.7 Ų76.785%0.85343%0.429SS*.  trans-82.731.4-173.248.80000112.5A2A2-T4 WeakPolarHBondContact O-CG2 3.42Å; A2-T4 PolarHBondContact O-N 3.39Å
5G82.6Confident80.9Confident37 Ų3780 Ų8038%0.38144%0.44SS..SBendtrans-142.7159.6-174.200000112.5E3E3-G5 PolarHBondContact O-N 2.87Å; E3-G5 VanDerWaalsContact O-N 3.08Å
6V92.5Very high81.3Confident20 Ų2081 Ų8112%0.12144%0.444CS..PPolyproline II helixtrans-79.7135.2170.3-1780000107.7L8 E198 R260 F262V6-L8 HydrophobicContact CG1-CD2 4.04Å; V6-E198 HydrophobicContact CB-CB 4.07Å; V6-E198 WeakPolarHBondContact CB-OE2 3.48Å; V6-E198 WeakPolarHBondContact O-CB 3.39Å; V6-E198 PolarHBondContact O-N 3.37Å; V6-R260 HydrophobicContact CG1-CB 4.06Å; V6-F262 HydrophobicContact CG1-CB 4.47Å; V6-F262 HydrophobicContact CG2-CB 4.12Å; V6-F262 HydrophobicContact CG2-CD1 4.03Å; V6-F262 HydrophobicContact CG2-CD2 4.36Å; V6-F262 HydrophobicContact CG2-CG 3.93Å
7A95.8Very high81.5Confident18 Ų1880.1 Ų80.115%0.14943%0.433CS..EExtended strand (participates in β ladder)trans-102.5128.4167.200000109.7E196 R260 Y261A7-E196 CarbonylContact C-O 3.49Å; A7-E196 VanDerWaalsContact CA-O 3.28Å; A7-E196 WeakPolarHBondContact CA-O 3.44Å; A7-R260 CarbonylContact O-C 3.44Å; A7-R260 WeakPolarHBondContact O-CA 3.25Å; A7-Y261 PolarHBondContact N-O 2.75Å; A7-Y261 PolarHBondContact O-N 3.31Å
8L97.2Very high81.9Confident5 Ų579.1 Ų79.13%0.02643%0.425CS..EExtended strand (participates in β ladder)trans-89.6139.5175.3-50.8-174.1000108.7V6 F10 T195 E196 E198 E254 Q257 L259 R260V6-L8 HydrophobicContact CG1-CD2 4.04Å; L8-F10 HydrophobicContact CB-CE2 3.76Å; L8-F10 HydrophobicContact CB-CZ 3.88Å; L8-F10 HydrophobicContact CD1-CZ 4.29Å; L8-T195 CarbonylContact O-C 3.57Å; L8-T195 WeakPolarHBondContact O-CA 3.38Å; L8-E196 PolarHBondContact N-O 3.47Å; L8-E196 PolarHBondContact O-N 2.63Å; L8-E198 HydrophobicContact CD1-CB 4.23Å; L8-E198 HydrophobicContact CD1-CG 4.25Å; L8-E198 HydrophobicContact CD2-CB 4.07Å; L8-E198 HydrophobicContact CD2-CG 4.33Å; L8-E198 HydrophobicContact CG-CB 3.95Å; L8-E198 HydrophobicContact CG-CG 4.41Å; L8-E254 HydrophobicContact CD1-CB 3.9Å; L8-E254 HydrophobicContact CD1-CG 3.83Å; L8-Q257 HydrophobicContact CB-CB 4.49Å; L8-L259 CarbonylContact C-O 3.49Å; L8-L259 WeakPolarHBondContact CA-O 3.4Å; L8-R260 HydrophobicContact CD2-CG 3.9Å
9G97.4Very high82.5Confident0 Ų075 Ų750%040%0.403CS..EExtended strand (participates in β ladder)trans-108.8139.9176.600000112.6V194 Q257 V258 L259G9-V194 CarbonylContact C-O 3.5Å; G9-V194 WeakPolarHBondContact CA-O 3.3Å; G9-Q257 CarbonylContact O-C 3.08Å; G9-Q257 WeakPolarHBondContact O-CA 3.44Å; G9-V258 WeakPolarHBondContact O-CG2 3.34Å; G9-V258 PolarHBondContact O-N 2.73Å; G9-L259 PolarHBondContact N-O 2.99Å; G9-L259 PolarHBondContact O-N 2.96Å
10F97.6Very high82.9Confident27 Ų2774.3 Ų74.312%0.11840%0.397CS..EExtended strand (participates in β ladder)trans-129.5157.7-178.9-55.9-83.1000110.2L8 L193 V194 E196 E254 Q257L8-F10 HydrophobicContact CB-CE2 3.76Å; L8-F10 HydrophobicContact CB-CZ 3.88Å; L8-F10 HydrophobicContact CD1-CZ 4.29Å; F10-L193 WeakPolarHBondContact O-CA 3.48Å; F10-V194 PolarHBondContact N-O 3.38Å; F10-V194 PolarHBondContact O-N 3.48Å; F10-E196 HydrophobicContact CD2-CG 4.38Å; F10-E196 HydrophobicContact CE2-CB 4.24Å; F10-E196 HydrophobicContact CE2-CG 4.38Å; F10-E254 HydrophobicContact CE1-CB 4.35Å; F10-E254 HydrophobicContact CZ-CB 4.25Å; F10-E254 HydrophobicContact CZ-CG 4.29Å; F10-Q257 HydrophobicContact CE1-CB 4.09Å; F10-Q257 HydrophobicContact CZ-CB 4.49Å
11L97.5Very high83.3Confident36 Ų3671.9 Ų71.919%0.18839%0.386CS..EExtended strand (participates in β ladder)trans-102.8131.7-178.8-60.9-178.9000111.5V28 L191 E192 L193 V258 L300 D303L11-V28 HydrophobicContact CD1-CG2 4.49Å; L11-V28 HydrophobicContact CD2-CB 4.05Å; L11-V28 HydrophobicContact CD2-CG2 3.54Å; L11-L191 HydrophobicContact CB-CB 4.39Å; L11-L191 HydrophobicContact CB-CD1 4.21Å; L11-L191 HydrophobicContact CD1-CD1 3.97Å; L11-L191 HydrophobicContact CD2-CB 4.44Å; L11-E192 WeakPolarHBondContact CA-O 3.49Å; L11-L193 HydrophobicContact CD2-CB 4.42Å; L11-L193 HydrophobicContact CD2-CD1 3.98Å; L11-V258 HydrophobicContact CD1-CG1 4.04Å; L11-V258 HydrophobicContact CD1-CG2 4.44Å; L11-V258 HydrophobicContact CD2-CG2 3.84Å; L11-V258 HydrophobicContact CG-CB 4.48Å; L11-V258 HydrophobicContact CG-CG1 4.05Å; L11-V258 HydrophobicContact CG-CG2 3.79Å; L11-L300 HydrophobicContact CD1-CD1 3.87Å; L11-D303 HydrophobicContact CD1-CB 3.61Å
12E96.3Very high86Confident96 Ų9663 Ų6345%0.44934%0.342SS..EExtended strand (participates in β ladder)trans-129.5155.4177.3-63.3-170.9-179.900111.1E192 V194E12-E192 PolarHBondContact N-O 2.87Å; E12-E192 PolarHBondContact O-N 2.84Å; E12-V194 HydrophobicContact CB-CG2 4.33Å; E12-V194 HydrophobicContact CG-CG2 4.09Å
13E95.2Very high88.6Confident184 Ų18461 Ų6186%0.8632%0.318SS*.  trans-74134.5170-65.8-170.9170.100109.5L191E13-L191 HydrophobicContact CG-CD2 4.34Å
14A90.8Very high90.6Very high28 Ų2854.4 Ų54.423%0.23129%0.286CS..  trans-136.8153.717600000110.8Q18 L19 E192A14-Q18 HydrophobicContact CB-CB 4.44Å; A14-L19 HydrophobicContact CB-CD1 4.19Å; A14-L19 HydrophobicContact CB-CD2 4.07Å; A14-L19 HydrophobicContact CB-CG 4.09Å; A14-E192 HydrophobicContact CB-CB 3.75Å
15E89.4Confident92.2Very high126 Ų12648 Ų4859%0.58925%0.247SC*.  trans-70.4147.6174.8-60.4-165.3145.100110.5W17 Q18E15-W17 PolarHBondContact O-N 3.38Å; E15-W17 PolarHBondContact OE2-NE1 3.4Å; E15-Q18 HydrophobicContact CB-CG 4.41Å; E15-Q18 WeakPolarHBondContact O-CB 3.48Å; E15-Q18 PolarHBondContact O-N 3.2Å
16N86.9Confident93Very high96 Ų9647.3 Ų47.351%0.51324%0.236SC..THydrogen-bonded Turntrans-59.5-30.3-171.6-174.9-103.4000113.6Q18 L19 Q20 E190N16-Q18 VanDerWaalsContact C-N 3.33Å; N16-L19 PolarHBondContact O-N 2.91Å; N16-Q20 WeakPolarHBondContact O-CG 3.42Å; N16-Q20 PolarHBondContact O-NE2 3.05Å; N16-Q20 PolarHBondContact OD1-NE2 3.28Å; N16-E190 PolarHBondContact ND2-OE2 3.11Å
17W85.2Confident93.2Very high65 Ų6546.4 Ų46.425%0.24623%0.231CC..THydrogen-bonded Turntrans-69.4-29.9178.968.6-93.2000112.7E15 L19 Q20 Q23E15-W17 PolarHBondContact O-N 3.38Å; E15-W17 PolarHBondContact OE2-NE1 3.4Å; W17-L19 PolarHBondContact O-N 2.77Å; W17-Q20 WeakPolarHBondContact O-CB 3.24Å; W17-Q20 WeakPolarHBondContact O-CG 3.15Å; W17-Q20 PolarHBondContact O-N 3.4Å; W17-Q23 WeakPolarHBondContact O-CG 3.38Å
18Q89.3Confident93.3Very high62 Ų6245.6 Ų45.629%0.2922%0.224SC..THydrogen-bonded Turntrans-67.6-26.2176.3-60.9176-76.200111.4A14 E15 N16 Q23A14-Q18 HydrophobicContact CB-CB 4.44Å; E15-Q18 HydrophobicContact CB-CG 4.41Å; E15-Q18 WeakPolarHBondContact O-CB 3.48Å; E15-Q18 PolarHBondContact O-N 3.2Å; N16-Q18 VanDerWaalsContact C-N 3.33Å; Q18-Q23 WeakPolarHBondContact O-CB 3.47Å
19L92.4Very high93.3Very high2 Ų245.4 Ų45.41%0.0122%0.223CC..THydrogen-bonded Turntrans-96.816.3-175.5-56.7-176.7000113.9A14 N16 W17 P25 K27 E190 E192A14-L19 HydrophobicContact CB-CD1 4.19Å; A14-L19 HydrophobicContact CB-CD2 4.07Å; A14-L19 HydrophobicContact CB-CG 4.09Å; N16-L19 PolarHBondContact O-N 2.91Å; W17-L19 PolarHBondContact O-N 2.77Å; L19-P25 HydrophobicContact CD2-CB 4.15Å; L19-K27 HydrophobicContact CB-CD 4.21Å; L19-K27 HydrophobicContact CD2-CB 4.11Å; L19-K27 PolarHBondContact O-NZ 3.13Å; L19-K27 VanDerWaalsContact O-NZ 3.15Å; L19-E190 HydrophobicContact CD1-CG 3.59Å; L19-E192 HydrophobicContact CD2-CB 4.02Å; L19-E192 HydrophobicContact CD2-CG 4.36Å
20Q90.3Very high93.1Very high61 Ų6145.6 Ų45.629%0.28523%0.225SC..SBendtrans-89.9156.4178.4-59.9-58-47.400112.4N16 W17 H22 Q23 P25N16-Q20 WeakPolarHBondContact O-CG 3.42Å; N16-Q20 PolarHBondContact O-NE2 3.05Å; N16-Q20 PolarHBondContact OD1-NE2 3.28Å; W17-Q20 WeakPolarHBondContact O-CB 3.24Å; W17-Q20 WeakPolarHBondContact O-CG 3.15Å; W17-Q20 PolarHBondContact O-N 3.4Å; Q20-H22 VanDerWaalsContact CB-CE1 3.46Å; Q20-H22 WeakPolarHBondContact CB-CE1 3.37Å; Q20-H22 WeakPolarHBondContact CB-ND1 3.13Å; Q20-H22 PolarHBondContact O-N 2.81Å; Q20-Q23 PolarHBondContact O-N 2.85Å; Q20-P25 VanDerWaalsContact O-CD 3.25Å; Q20-P25 WeakPolarHBondContact O-CD 3.32Å
21S91.9Very high93Very high23 Ų2347.7 Ų47.716%0.16123%0.234CC..THydrogen-bonded Turntrans-54.7-25.7-176.6-60.10000115.9Q23 A33 W34 Y109S21-Q23 VanDerWaalsContact C-N 3.33Å; S21-A33 VanDerWaalsContact OG-CA 3.31Å; S21-A33 WeakPolarHBondContact OG-CA 3.17Å; S21-W34 VanDerWaalsContact CB-O 3.24Å; S21-W34 WeakPolarHBondContact CB-O 3.44Å; S21-W34 PolarHBondContact OG-N 3.48Å; S21-W34 VanDerWaalsContact OG-N 3.14Å; S21-W34 PolarHBondContact OG-O 3.49Å; S21-Y109 WeakPolarHBondContact CB-OH 3.25Å; S21-Y109 WeakPolarHBondContact O-CE1 3.27Å; S21-Y109 PolarHBondContact O-OH 2.99Å
22H88.1Confident93Very high38 Ų3846.4 Ų46.418%0.17623%0.228CC..THydrogen-bonded Turntrans-80.8-14.4-179.666-90000113.8Q20 F24 Y109Q20-H22 VanDerWaalsContact CB-CE1 3.46Å; Q20-H22 WeakPolarHBondContact CB-CE1 3.37Å; Q20-H22 WeakPolarHBondContact CB-ND1 3.13Å; Q20-H22 PolarHBondContact O-N 2.81Å; H22-F24 WeakPolarHBondContact O-CD2 3.17Å; H22-F24 WeakPolarHBondContact O-CE2 3.14Å; H22-Y109 HydrophobicContact CB-CD1 4.27Å; H22-Y109 HydrophobicContact CB-CE1 4.18Å
23Q90.8Very high92.9Very high46 Ų4642.1 Ų42.122%0.21521%0.209CC..SBendtrans-92.4-4.8174.2-60.1-61.8-15.800112.3W17 Q18 Q20 S21W17-Q23 WeakPolarHBondContact O-CG 3.38Å; Q18-Q23 WeakPolarHBondContact O-CB 3.47Å; Q20-Q23 PolarHBondContact O-N 2.85Å; S21-Q23 VanDerWaalsContact C-N 3.33Å
24F93.9Very high93Very high33 Ų3333.5 Ų33.515%0.14517%0.168CC..  trans51.650.8-179.5-49.8-80000114H22 L35 Y62 H73 Y109H22-F24 WeakPolarHBondContact O-CD2 3.17Å; H22-F24 WeakPolarHBondContact O-CE2 3.14Å; F24-L35 HydrophobicContact CD1-CD1 3.63Å; F24-L35 HydrophobicContact CE1-CD1 3.68Å; F24-Y62 HydrophobicContact CB-CD2 3.83Å; F24-Y62 HydrophobicContact CB-CE1 4.49Å; F24-Y62 HydrophobicContact CB-CE2 3.77Å; F24-Y62 HydrophobicContact CB-CG 4.21Å; F24-Y62 HydrophobicContact CD1-CE2 4.19Å; F24-Y62 HydrophobicContact CG-CE2 4.19Å; F24-Y62 WeakPolarHBondContact O-CB 2.88Å; F24-H73 AromaticContact CD1-ND1 3.65Å; F24-H73 HydrophobicContact CE1-CB 4.39Å; F24-H73 AromaticContact CE1-CE1 3.7Å; F24-H73 AromaticContact CE1-CG 3.78Å; F24-H73 AromaticContact CE1-ND1 3.46Å; F24-H73 WeakPolarHBondContact CE1-ND1 3.33Å; F24-H73 AromaticContact CE2-CE1 3.67Å; F24-H73 AromaticContact CZ-CE1 3.41Å; F24-H73 VanDerWaalsContact CZ-CE1 3.41Å; F24-H73 WeakPolarHBondContact CZ-CE1 3.37Å; F24-H73 AromaticContact CZ-ND1 3.69Å; F24-H73 AromaticContact CZ-NE2 3.84Å; F24-Y109 HydrophobicContact CE1-CD1 4.09Å; F24-Y109 AromaticContact CE1-CD2 3.67Å; F24-Y109 HydrophobicContact CE1-CD2 3.67Å; F24-Y109 HydrophobicContact CE1-CE1 4.08Å; F24-Y109 AromaticContact CE1-CE2 3.66Å; F24-Y109 HydrophobicContact CE1-CE2 3.66Å; F24-Y109 AromaticContact CE1-CG 3.86Å; F24-Y109 HydrophobicContact CE1-CG 3.86Å; F24-Y109 AromaticContact CE1-CZ 3.83Å; F24-Y109 AromaticContact CZ-CD1 3.76Å; F24-Y109 HydrophobicContact CZ-CD1 3.76Å; F24-Y109 AromaticContact CZ-CD2 3.82Å; F24-Y109 HydrophobicContact CZ-CD2 3.82Å; F24-Y109 HydrophobicContact CZ-CE1 4.17Å; F24-Y109 HydrophobicContact CZ-CE2 4.22Å; F24-Y109 AromaticContact CZ-CG 3.54Å; F24-Y109 HydrophobicContact CZ-CG 3.54Å
25P95.6Very high93.1Very high6 Ų632.2 Ų32.24%0.03916%0.158CC..  trans-71.9147.8-168.431.2-38000112.3L19 Q20 K27 A33 Q60L19-P25 HydrophobicContact CD2-CB 4.15Å; Q20-P25 VanDerWaalsContact O-CD 3.25Å; Q20-P25 WeakPolarHBondContact O-CD 3.32Å; P25-K27 HydrophobicContact CB-CB 4.49Å; P25-K27 HydrophobicContact CB-CD 4.22Å; P25-K27 HydrophobicContact CB-CG 4.37Å; P25-K27 HydrophobicContact CG-CD 3.81Å; P25-K27 HydrophobicContact CG-CG 4.32Å; P25-A33 HydrophobicContact CG-CB 3.77Å; P25-Q60 PolarHBondContact O-NE2 3.38Å
26S98.3Very high93.3Very high21 Ų2126.2 Ų26.215%0.14713%0.13CC..  trans-88.9126.2150.1-700000107.4Q60 Y62 L193S26-Q60 CarbonylContact C-O 3.55Å; S26-Q60 WeakPolarHBondContact CA-O 3.22Å; S26-Y62 PolarHBondContact OG-N 3.38Å; S26-L193 VanDerWaalsContact CB-O 3.25Å; S26-L193 WeakPolarHBondContact CB-O 3.47Å; S26-L193 PolarHBondContact O-N 3.01Å
27K98.1Very high93.4Very high2 Ų222.3 Ų22.31%0.00911%0.108CC..EExtended strand (participates in β ladder)trans-157.8158.6-172.860.3-179.2-72.2-167.30113.2L19 P25 G29 K31 A33 F57 M59 Q60 E190 L191L19-K27 HydrophobicContact CB-CD 4.21Å; L19-K27 HydrophobicContact CD2-CB 4.11Å; L19-K27 PolarHBondContact O-NZ 3.13Å; L19-K27 VanDerWaalsContact O-NZ 3.15Å; P25-K27 HydrophobicContact CB-CB 4.49Å; P25-K27 HydrophobicContact CB-CD 4.22Å; P25-K27 HydrophobicContact CB-CG 4.37Å; P25-K27 HydrophobicContact CG-CD 3.81Å; P25-K27 HydrophobicContact CG-CG 4.32Å; K27-G29 WeakPolarHBondContact CE-O 3.46Å; K27-K31 PolarHBondContact NZ-O 2.81Å; K27-A33 HydrophobicContact CD-CB 4.33Å; K27-F57 HydrophobicContact CG-CE1 4.47Å; K27-M59 CarbonylContact O-C 3.58Å; K27-M59 WeakPolarHBondContact O-CA 3.3Å; K27-M59 WeakPolarHBondContact O-CB 3.2Å; K27-Q60 HydrophobicContact CD-CG 4.36Å; K27-Q60 HydrophobicContact CG-CG 3.59Å; K27-Q60 PolarHBondContact N-O 3.04Å; K27-Q60 PolarHBondContact O-N 2.84Å; K27-E190 WeakPolarHBondContact CE-OE1 3.45Å; K27-E190 IonicContact NZ-OE1 3.96Å; K27-E190 PolarHBondContact NZ-OE1 2.8Å; K27-L191 CarbonylContact C-O 3.53Å; K27-L191 VanDerWaalsContact CA-O 3.28Å; K27-L191 WeakPolarHBondContact CA-O 3.49Å; K27-L191 VanDerWaalsContact CB-O 3.28Å; K27-L191 WeakPolarHBondContact CB-O 3.49Å
28V97.8Very high93.6Very high1 Ų122.5 Ų22.51%0.00611%0.114CC..EExtended strand (participates in β ladder)trans-108.7141.8169.6169.60000109.5L11 M59 E190 L191 L300 L304L11-V28 HydrophobicContact CD1-CG2 4.49Å; L11-V28 HydrophobicContact CD2-CB 4.05Å; L11-V28 HydrophobicContact CD2-CG2 3.54Å; V28-M59 HydrophobicContact CG2-CB 3.91Å; V28-M59 HydrophobicContact CG2-CE 4.14Å; V28-E190 WeakPolarHBondContact O-CA 3.32Å; V28-L191 PolarHBondContact N-O 2.9Å; V28-L191 PolarHBondContact O-N 2.79Å; V28-L300 HydrophobicContact CB-CD1 4.44Å; V28-L300 HydrophobicContact CG1-CD1 3.85Å; V28-L300 HydrophobicContact CG2-CD1 3.79Å; V28-L304 HydrophobicContact CG1-CD2 3.87Å
29G95.6Very high93.6Very high0 Ų024.2 Ų24.20%013%0.125CC..SBendtrans60.3-162.7171.300000115.5K27 F57 L58 P189K27-G29 WeakPolarHBondContact CE-O 3.46Å; G29-F57 VanDerWaalsContact O-CD1 3.24Å; G29-F57 WeakPolarHBondContact O-CD1 3.17Å; G29-F57 WeakPolarHBondContact O-CE1 3.36Å; G29-L58 PolarHBondContact N-O 2.89Å; G29-P189 VanDerWaalsContact CA-O 3.32Å; G29-P189 WeakPolarHBondContact CA-O 3.44Å
30G94.5Very high93.7Very high5 Ų524.9 Ų24.95%0.05213%0.129CC..SBendtrans62.1-148.5-167.500000112.7L187 F188G30-L187 WeakPolarHBondContact O-CD2 3.17Å; G30-F188 PolarHBondContact N-O 3.09Å
31K95.5Very high93.9Very high70 Ų7022 Ų2230%0.30412%0.115SC..SBendtrans-94.4148.4175.3-67.7177.2-179.9173.90110.3K27 A33 K137 L187K27-K31 PolarHBondContact NZ-O 2.81Å; K31-A33 PolarHBondContact O-N 2.99Å; K31-K137 VanDerWaalsContact CE-O 3.24Å; K31-K137 WeakPolarHBondContact CE-O 3.19Å; K31-K137 PolarHBondContact NZ-O 2.93Å; K31-L187 HydrophobicContact CG-CD1 4.01Å; K31-L187 HydrophobicContact CG-CD2 4.41Å
32P96.5Very high94Very high10 Ų1021.4 Ų21.47%0.06511%0.113CC..  trans-58.3130.6173.7-15.424.8000110.6W34 F57 F77 F79 C139P32-W34 VanDerWaalsContact C-N 3.3Å; P32-W34 HydrophobicContact CB-CD2 3.82Å; P32-W34 HydrophobicContact CB-CE3 4.18Å; P32-W34 HydrophobicContact CB-CG 4.33Å; P32-W34 HydrophobicContact CB-CH2 4.28Å; P32-W34 HydrophobicContact CB-CZ2 3.86Å; P32-W34 HydrophobicContact CB-CZ3 4.41Å; P32-W34 HydrophobicContact CG-CH2 4.31Å; P32-W34 HydrophobicContact CG-CZ2 3.71Å; P32-W34 PolarHBondContact O-N 3.15Å; P32-W34 VanDerWaalsContact O-N 3.16Å; P32-F57 HydrophobicContact CB-CD2 3.88Å; P32-F57 HydrophobicContact CB-CE2 4.06Å; P32-F57 HydrophobicContact CB-CG 4.19Å; P32-F57 HydrophobicContact CG-CB 3.81Å; P32-F57 HydrophobicContact CG-CD1 4.4Å; P32-F57 HydrophobicContact CG-CD2 3.69Å; P32-F57 HydrophobicContact CG-CE2 4.37Å; P32-F57 HydrophobicContact CG-CG 3.69Å; P32-F77 HydrophobicContact CB-CD1 4.37Å; P32-F77 HydrophobicContact CB-CE1 4.47Å; P32-F79 HydrophobicContact CB-CZ 4.44Å; P32-F79 HydrophobicContact CG-CE1 3.85Å; P32-F79 HydrophobicContact CG-CZ 3.96Å; P32-C139 VanDerWaalsContact CD-O 3.31Å; P32-C139 WeakPolarHBondContact CD-O 3.45Å
33A95.4Very high94.3Very high5 Ų521.7 Ų21.74%0.04112%0.115CC..  trans-85.980.3167.700000107.8S21 P25 K27 K31 L35 Q60 F77S21-A33 VanDerWaalsContact OG-CA 3.31Å; S21-A33 WeakPolarHBondContact OG-CA 3.17Å; P25-A33 HydrophobicContact CG-CB 3.77Å; K27-A33 HydrophobicContact CD-CB 4.33Å; K31-A33 PolarHBondContact O-N 2.99Å; A33-L35 PolarHBondContact O-N 3.41Å; A33-Q60 PolarHBondContact O-NE2 3.28Å; A33-F77 WeakPolarHBondContact O-CE1 3.5Å
34W95.9Very high94.4Very high3 Ų324.1 Ų24.11%0.01114%0.135CC..  trans-57.8125.8-176.2-64.5118000111.8S21 P32 I40 L46 F77 F79 Y109 G140 Y333S21-W34 VanDerWaalsContact CB-O 3.24Å; S21-W34 WeakPolarHBondContact CB-O 3.44Å; S21-W34 PolarHBondContact OG-N 3.48Å; S21-W34 VanDerWaalsContact OG-N 3.14Å; S21-W34 PolarHBondContact OG-O 3.49Å; P32-W34 VanDerWaalsContact C-N 3.3Å; P32-W34 HydrophobicContact CB-CD2 3.82Å; P32-W34 HydrophobicContact CB-CE3 4.18Å; P32-W34 HydrophobicContact CB-CG 4.33Å; P32-W34 HydrophobicContact CB-CH2 4.28Å; P32-W34 HydrophobicContact CB-CZ2 3.86Å; P32-W34 HydrophobicContact CB-CZ3 4.41Å; P32-W34 HydrophobicContact CG-CH2 4.31Å; P32-W34 HydrophobicContact CG-CZ2 3.71Å; P32-W34 PolarHBondContact O-N 3.15Å; P32-W34 VanDerWaalsContact O-N 3.16Å; W34-I40 HydrophobicContact CB-CD1 4.2Å; W34-I40 HydrophobicContact CD2-CG2 3.59Å; W34-I40 HydrophobicContact CE3-CG2 3.97Å; W34-I40 HydrophobicContact CG-CD1 3.99Å; W34-I40 HydrophobicContact CG-CG1 4.37Å; W34-I40 HydrophobicContact CG-CG2 4.13Å; W34-I40 HydrophobicContact CH2-CG2 3.86Å; W34-I40 HydrophobicContact CZ2-CG2 3.52Å; W34-I40 HydrophobicContact CZ3-CG2 4.1Å; W34-L46 HydrophobicContact CH2-CD1 4.36Å; W34-F77 HydrophobicContact CE3-CD1 4.23Å; W34-F77 HydrophobicContact CE3-CE1 4.03Å; W34-F77 HydrophobicContact CE3-CZ 4.3Å; W34-F77 HydrophobicContact CZ3-CD1 4.22Å; W34-F77 HydrophobicContact CZ3-CE1 4.48Å; W34-F77 HydrophobicContact CZ3-CG 4.38Å; W34-F79 HydrophobicContact CH2-CE1 4.24Å; W34-F79 HydrophobicContact CH2-CE2 4.11Å; W34-F79 AromaticContact CH2-CZ 3.39Å; W34-F79 HydrophobicContact CH2-CZ 3.39Å; W34-F79 HydrophobicContact CZ2-CZ 4.06Å; W34-F79 HydrophobicContact CZ3-CE2 4.45Å; W34-F79 HydrophobicContact CZ3-CZ 4.01Å; W34-Y109 PolarHBondContact O-OH 2.86Å; W34-G140 PolarHBondContact NE1-O 3.43Å; W34-Y333 HydrophobicContact CE3-CD1 4.35Å; W34-Y333 AromaticContact CE3-CE1 3.42Å; W34-Y333 HydrophobicContact CE3-CE1 3.42Å; W34-Y333 VanDerWaalsContact CE3-CE1 3.42Å; W34-Y333 AromaticContact CE3-CZ 3.58Å; W34-Y333 HydrophobicContact CZ3-CD1 4.09Å; W34-Y333 AromaticContact CZ3-CE1 3.59Å; W34-Y333 HydrophobicContact CZ3-CE1 3.59Å
35L94.6Very high94.5Very high2 Ų227 Ų271%0.0115%0.149CC..SBendtrans-73.6-63.9178.8-179.267.6000112F24 A33 H73 F77 S100 L102 Y109 Y333F24-L35 HydrophobicContact CD1-CD1 3.63Å; F24-L35 HydrophobicContact CE1-CD1 3.68Å; A33-L35 PolarHBondContact O-N 3.41Å; L35-H73 HydrophobicContact CD1-CB 3.89Å; L35-H73 HydrophobicContact CD2-CB 4.15Å; L35-F77 HydrophobicContact CB-CZ 4.3Å; L35-S100 WeakPolarHBondContact CD2-O 3.24Å; L35-L102 HydrophobicContact CD1-CD1 3.94Å; L35-L102 HydrophobicContact CD2-CD1 4.38Å; L35-L102 HydrophobicContact CD2-CG 4.23Å; L35-L102 HydrophobicContact CG-CD1 3.71Å; L35-L102 HydrophobicContact CG-CG 4.06Å; L35-Y109 WeakPolarHBondContact CA-OH 3.15Å; L35-Y109 HydrophobicContact CD1-CE2 3.85Å; L35-Y109 WeakPolarHBondContact O-CE2 3.48Å; L35-Y109 PolarHBondContact O-OH 2.83Å; L35-Y333 PolarHBondContact N-OH 2.74Å; L35-Y333 VanDerWaalsContact N-OH 3.11Å
36S92.6Very high94.6Very high0 Ų027 Ų270%015%0.148CC..SBendtrans-79.8130.9171.2173.50000109.3L38 N331 Y333S36-L38 PolarHBondContact O-N 2.84Å; S36-L38 PolarHBondContact OG-N 3.33Å; S36-L38 PolarHBondContact OG-O 3.49Å; S36-N331 WeakPolarHBondContact CB-O 3.35Å; S36-N331 WeakPolarHBondContact OG-CB 3.21Å; S36-N331 PolarHBondContact OG-O 3.32Å; S36-Y333 PolarHBondContact N-OH 3.27Å; S36-Y333 VanDerWaalsContact N-OH 3.14Å; S36-Y333 PolarHBondContact O-OH 2.92Å
37Q88.9Confident94.5Very high14 Ų1428.7 Ų28.77%0.06515%0.154CC..SBendtrans-84.90.2179.8-47-161.15.100112.2F108 H129 S130 S131Q37-F108 HydrophobicContact CB-CD1 3.58Å; Q37-F108 HydrophobicContact CB-CE1 3.69Å; Q37-F108 HydrophobicContact CB-CG 4.33Å; Q37-F108 HydrophobicContact CG-CB 3.95Å; Q37-F108 HydrophobicContact CG-CD1 3.44Å; Q37-F108 VanDerWaalsContact CG-CD1 3.44Å; Q37-F108 HydrophobicContact CG-CE1 4.07Å; Q37-F108 HydrophobicContact CG-CG 3.77Å; Q37-H129 WeakPolarHBondContact CB-CE1 3.46Å; Q37-H129 VanDerWaalsContact CB-ND1 3.32Å; Q37-H129 WeakPolarHBondContact CB-ND1 3.13Å; Q37-H129 WeakPolarHBondContact CG-CE1 3.5Å; Q37-H129 WeakPolarHBondContact CG-ND1 3.47Å; Q37-H129 PolarHBondContact NE2-CE1 3.09Å; Q37-H129 PolarHBondContact OE1-CE1 3.36Å; Q37-H129 PolarHBondContact OE1-ND1 2.9Å; Q37-S130 PolarHBondContact OE1-OG 3.08Å; Q37-S131 WeakPolarHBondContact O-CB 3.22Å; Q37-S131 PolarHBondContact O-OG 2.86Å
38L88.9Confident94.5Very high68 Ų6828.6 Ų28.636%0.35615%0.154SC..SBendtrans-119.6157.5179.7-64.6176.2000109.7S36 I40 F108 N331S36-L38 PolarHBondContact O-N 2.84Å; S36-L38 PolarHBondContact OG-N 3.33Å; S36-L38 PolarHBondContact OG-O 3.49Å; L38-I40 PolarHBondContact O-N 3.36Å; L38-F108 HydrophobicContact CB-CZ 4.24Å; L38-F108 HydrophobicContact CD1-CE1 4.03Å; L38-F108 HydrophobicContact CD1-CZ 3.84Å; L38-F108 HydrophobicContact CG-CE1 3.86Å; L38-F108 HydrophobicContact CG-CZ 3.85Å; L38-N331 HydrophobicContact CB-CB 4.37Å
39D89.9Confident94.4Very high99 Ų9930 Ų3053%0.52917%0.169SC..SBendtrans50.734.2175-59.1-37.1000113.7K332 Y333D39-K332 HydrophobicContact CB-CB 4.42Å; D39-K332 HydrophobicContact CB-CG 3.87Å; D39-K332 WeakPolarHBondContact OD2-CG 3.37Å; D39-Y333 WeakPolarHBondContact O-CD2 3.24Å
40I94.1Very high94.4Very high16 Ų1632.5 Ų32.58%0.08218%0.179CC..  trans-63.1134.4176.2-59.3171.3000108.3W34 L38 G42 L135 P142 Y333W34-I40 HydrophobicContact CB-CD1 4.2Å; W34-I40 HydrophobicContact CD2-CG2 3.59Å; W34-I40 HydrophobicContact CE3-CG2 3.97Å; W34-I40 HydrophobicContact CG-CD1 3.99Å; W34-I40 HydrophobicContact CG-CG1 4.37Å; W34-I40 HydrophobicContact CG-CG2 4.13Å; W34-I40 HydrophobicContact CH2-CG2 3.86Å; W34-I40 HydrophobicContact CZ2-CG2 3.52Å; W34-I40 HydrophobicContact CZ3-CG2 4.1Å; L38-I40 PolarHBondContact O-N 3.36Å; I40-G42 PolarHBondContact O-N 3.11Å; I40-L135 HydrophobicContact CD1-CD2 4.47Å; I40-P142 HydrophobicContact CB-CG 3.65Å; I40-P142 HydrophobicContact CG2-CG 3.51Å; I40-Y333 HydrophobicContact CG1-CE2 4.22Å
41P95.3Very high94.5Very high0 Ų034.2 Ų34.20%019%0.19CC..  trans-53.5128.4-177.9-28.435.5000112.1E45 L46 F98 P142 Y333P41-E45 WeakPolarHBondContact CA-OE2 3.31Å; P41-E45 HydrophobicContact CB-CB 4.08Å; P41-L46 HydrophobicContact CB-CD1 4.03Å; P41-L46 HydrophobicContact CB-CD2 4.25Å; P41-L46 HydrophobicContact CB-CG 3.89Å; P41-L46 WeakPolarHBondContact O-CD1 3.43Å; P41-F98 HydrophobicContact CB-CE1 4.2Å; P41-F98 HydrophobicContact CB-CZ 4.22Å; P41-F98 HydrophobicContact CG-CD1 3.88Å; P41-F98 HydrophobicContact CG-CD2 4.44Å; P41-F98 HydrophobicContact CG-CE1 4.05Å; P41-F98 HydrophobicContact CG-CG 4.08Å; P41-F98 HydrophobicContact CG-CZ 4.42Å; P41-P142 VanDerWaalsContact O-CD 3.31Å; P41-P142 WeakPolarHBondContact O-CD 3.34Å; P41-Y333 VanDerWaalsContact CD-CG 3.48Å; P41-Y333 HydrophobicContact CG-CD1 4.13Å; P41-Y333 HydrophobicContact CG-CD2 4.39Å; P41-Y333 HydrophobicContact CG-CG 3.78Å
42G94.2Very high94.5Very high11 Ų1136.3 Ų36.311%0.11320%0.201CC..  trans-80.7178.6178.900000112.5I40 P44 E45 L46I40-G42 PolarHBondContact O-N 3.11Å; G42-P44 VanDerWaalsContact C-CD 3.42Å; G42-P44 VanDerWaalsContact C-N 3.34Å; G42-E45 PolarHBondContact N-OE2 3.3Å; G42-E45 VanDerWaalsContact N-OE2 3.15Å; G42-E45 PolarHBondContact O-N 2.9Å; G42-E45 VanDerWaalsContact O-N 3.12Å; G42-L46 WeakPolarHBondContact O-CB 3.47Å; G42-L46 PolarHBondContact O-N 3.25Å
43L93.4Very high94.5Very high43 Ų4339 Ų3923%0.22521%0.214CC..THydrogen-bonded Turntrans-53.2-42.1173.9-179.864.3000113.8E45 L46 E47 P54 C156L43-E45 PolarHBondContact O-N 3.49Å; L43-E45 VanDerWaalsContact O-N 3.16Å; L43-L46 CarbonylContact O-C 3.51Å; L43-L46 PolarHBondContact O-N 3.04Å; L43-L46 VanDerWaalsContact O-N 3.11Å; L43-E47 PolarHBondContact O-N 2.57Å; L43-P54 HydrophobicContact CD1-CB 3.77Å; L43-P54 HydrophobicContact CD1-CG 3.69Å; L43-C156 WeakPolarHBondContact CD2-O 3.42Å
44P94.4Very high94.5Very high97 Ų9739.3 Ų39.363%0.6322%0.216SC*.THydrogen-bonded Turntrans-61.7-24.2179.8-24.535.7000114.4G42G42-P44 VanDerWaalsContact C-CD 3.42Å; G42-P44 VanDerWaalsContact C-N 3.34Å
45E95.8Very high94.5Very high95 Ų9539.3 Ų39.344%0.44422%0.216SC..THydrogen-bonded Turntrans-90.6-29.7177.2-65.3171.196.700111.6P41 G42 L43 F98P41-E45 WeakPolarHBondContact CA-OE2 3.31Å; P41-E45 HydrophobicContact CB-CB 4.08Å; G42-E45 PolarHBondContact N-OE2 3.3Å; G42-E45 VanDerWaalsContact N-OE2 3.15Å; G42-E45 PolarHBondContact O-N 2.9Å; G42-E45 VanDerWaalsContact O-N 3.12Å; L43-E45 PolarHBondContact O-N 3.49Å; L43-E45 VanDerWaalsContact O-N 3.16Å; E45-F98 HydrophobicContact CB-CE1 4.33Å; E45-F98 HydrophobicContact CB-CZ 3.99Å
46L96.4Very high94.6Very high5 Ų539.2 Ų39.23%0.02622%0.215CC..SBendtrans-100.520.8-178.4-64.3173000113.5W34 P41 G42 L43 T55 F79 F98 C141W34-L46 HydrophobicContact CH2-CD1 4.36Å; P41-L46 HydrophobicContact CB-CD1 4.03Å; P41-L46 HydrophobicContact CB-CD2 4.25Å; P41-L46 HydrophobicContact CB-CG 3.89Å; P41-L46 WeakPolarHBondContact O-CD1 3.43Å; G42-L46 WeakPolarHBondContact O-CB 3.47Å; G42-L46 PolarHBondContact O-N 3.25Å; L43-L46 CarbonylContact O-C 3.51Å; L43-L46 PolarHBondContact O-N 3.04Å; L43-L46 VanDerWaalsContact O-N 3.11Å; L46-T55 PolarHBondContact O-N 2.97Å; L46-T55 PolarHBondContact O-OG1 3.18Å; L46-F79 HydrophobicContact CD2-CD1 4.01Å; L46-F79 HydrophobicContact CD2-CD2 3.8Å; L46-F79 HydrophobicContact CD2-CE1 4.09Å; L46-F79 HydrophobicContact CD2-CE2 3.88Å; L46-F79 HydrophobicContact CD2-CG 3.89Å; L46-F79 HydrophobicContact CD2-CZ 4.05Å; L46-F98 HydrophobicContact CD2-CD2 4.16Å; L46-F98 HydrophobicContact CD2-CE2 3.54Å; L46-F98 HydrophobicContact CD2-CZ 4.27Å; L46-C141 HydrophobicContact CD1-CB 3.98Å
47E96.8Very high94.9Very high57 Ų5739.4 Ų39.427%0.26622%0.216SC..BIsolated β-bridgetrans-91.6143.6170.363.6174.1-133.500111.2L43 G49 H52 K96L43-E47 PolarHBondContact O-N 2.57Å; E47-G49 PolarHBondContact O-N 3.05Å; E47-H52 IonicContact OE1-CE1 2.93Å; E47-H52 IonicContact OE1-CG 2.91Å; E47-H52 IonicContact OE1-ND1 3.09Å; E47-H52 PolarHBondContact OE1-ND1 2.99Å; E47-K96 WeakPolarHBondContact O-CE 3.44Å; E47-K96 PolarHBondContact O-NZ 3.49Å
48C97.3Very high95.3Very high0 Ų038.8 Ų38.80%021%0.213CC..  trans-61.4131.2173.8175.40000109.9K50 C51 H52 L53 T55 C81C48-K50 PolarHBondContact O-N 3.27Å; C48-K50 PolarHBondContact SG-N 3.14Å; C48-C51 VanDerWaalsContact CB-SG 3.53Å; C48-C51 VanDerWaalsContact SG-SG 3.66Å; C48-H52 VanDerWaalsContact O-CA 3.24Å; C48-H52 WeakPolarHBondContact O-CA 3.42Å; C48-H52 PolarHBondContact O-N 3.21Å; C48-L53 PolarHBondContact N-O 3.28Å; C48-T55 HydrophobicContact CB-CG2 4.25Å; C48-C81 HydrophobicContact CB-CB 3.98Å; C48-C81 VanDerWaalsContact SG-SG 3.63Å
49G96.4Very high95.8Very high31 Ų3135.5 Ų35.532%0.3220%0.196SC..THydrogen-bonded Turntrans-70.57179.300000115.2E47 R93E47-G49 PolarHBondContact O-N 3.05Å; G49-R93 WeakPolarHBondContact CA-O 3.4Å; G49-R93 PolarHBondContact N-O 2.85Å
50K96.3Very high96.2Very high52 Ų5230.9 Ų30.923%0.22617%0.171CC..THydrogen-bonded Turntrans-119.6-59.2177.9-66.8-178.3178.4-177.20112.2C48 C86 S88 D91 R93C48-K50 PolarHBondContact O-N 3.27Å; C48-K50 PolarHBondContact SG-N 3.14Å; K50-C86 HydrophobicContact CB-CB 4.37Å; K50-C86 HydrophobicContact CD-CB 4.04Å; K50-C86 VanDerWaalsContact CD-O 3.26Å; K50-C86 WeakPolarHBondContact CD-O 3.47Å; K50-C86 WeakPolarHBondContact CE-O 3.17Å; K50-C86 PolarHBondContact NZ-O 2.91Å; K50-S88 PolarHBondContact NZ-OG 2.98Å; K50-D91 VanDerWaalsContact CE-CG 3.4Å; K50-D91 WeakPolarHBondContact CE-OD2 3.33Å; K50-D91 VanDerWaalsContact NZ-CG 3.3Å; K50-D91 IonicContact NZ-OD1 3.1Å; K50-D91 IonicContact NZ-OD2 3.88Å; K50-D91 PolarHBondContact NZ-OD2 2.72Å; K50-R93 HydrophobicContact CG-CB 4.17Å
51C95.8Very high96.4Very high40 Ų4030.3 Ų30.327%0.2717%0.169SC..THydrogen-bonded Turntrans-94.7-7.8-177.667.30000113.9C48 L53 C81C48-C51 VanDerWaalsContact CB-SG 3.53Å; C48-C51 VanDerWaalsContact SG-SG 3.66Å; C51-L53 HydrophobicContact CB-CD1 4.4Å; C51-L53 HydrophobicContact CB-CG 4.25Å; C51-L53 PolarHBondContact O-N 3.36Å; C51-C81 PolarHBondContact SG-SG 3.12Å
52H96.2Very high96.5Very high115 Ų11533.1 Ų33.153%0.53218%0.18SC..  trans57.313.9-176.1-55.5-80000114.9E47 C48E47-H52 IonicContact OE1-CE1 2.93Å; E47-H52 IonicContact OE1-CG 2.91Å; E47-H52 IonicContact OE1-ND1 3.09Å; E47-H52 PolarHBondContact OE1-ND1 2.99Å; C48-H52 VanDerWaalsContact O-CA 3.24Å; C48-H52 WeakPolarHBondContact O-CA 3.42Å; C48-H52 PolarHBondContact O-N 3.21Å
53L95.3Very high96.6Very high67 Ų6732.7 Ų32.735%0.35118%0.175SC..PPolyproline II helixtrans-79.4153.2170.5-59.3176000110C48 C51 T55 E159C48-L53 PolarHBondContact N-O 3.28Å; C51-L53 HydrophobicContact CB-CD1 4.4Å; C51-L53 HydrophobicContact CB-CG 4.25Å; C51-L53 PolarHBondContact O-N 3.36Å; L53-T55 PolarHBondContact O-N 3.34Å; L53-E159 HydrophobicContact CD2-CG 3.79Å
54P95.9Very high96.7Very high11 Ų1133.6 Ų33.67%0.07118%0.183CC..BIsolated β-bridgetrans-58.7136.2176.8-1524.2000111.8L43 S157 H160L43-P54 HydrophobicContact CD1-CB 3.77Å; L43-P54 HydrophobicContact CD1-CG 3.69Å; P54-S157 VanDerWaalsContact CG-OG 3.3Å; P54-S157 WeakPolarHBondContact CG-OG 3.47Å; P54-H160 WeakPolarHBondContact CB-NE2 3.36Å
55T96.8Very high96.7Very high2 Ų230.4 Ų30.41%0.01216%0.161CC..PPolyproline II helixtrans-77.4147.7172.655.90000111.3L46 C48 L53 F79 C80 K96L46-T55 PolarHBondContact O-N 2.97Å; L46-T55 PolarHBondContact O-OG1 3.18Å; C48-T55 HydrophobicContact CB-CG2 4.25Å; L53-T55 PolarHBondContact O-N 3.34Å; T55-F79 WeakPolarHBondContact OG1-CB 3.44Å; T55-C80 CarbonylContact C-O 3.58Å; T55-C80 WeakPolarHBondContact CA-O 3.42Å; T55-C80 WeakPolarHBondContact CB-O 3.37Å; T55-K96 HydrophobicContact CG2-CG 4.35Å
56A96.3Very high96.4Very high0 Ų032 Ų320%018%0.177CC..EExtended strand (participates in β ladder)trans-84.9148.7171.100000110.6L58 F79 C80 K82 F186 F188A56-L58 PolarHBondContact O-N 2.91Å; A56-F79 CarbonylContact O-C 3.59Å; A56-F79 WeakPolarHBondContact O-CA 3.5Å; A56-F79 WeakPolarHBondContact O-CB 3.46Å; A56-C80 PolarHBondContact N-O 2.87Å; A56-C80 PolarHBondContact O-N 2.67Å; A56-K82 HydrophobicContact CB-CD 3.87Å; A56-K82 HydrophobicContact CB-CG 3.86Å; A56-F186 HydrophobicContact CB-CE1 3.86Å; A56-F186 HydrophobicContact CB-CE2 4.32Å; A56-F186 HydrophobicContact CB-CZ 3.75Å; A56-F188 HydrophobicContact CB-CD2 4.45Å; A56-F188 HydrophobicContact CB-CE2 3.82Å; A56-F188 HydrophobicContact CB-CZ 4.41Å
57F97.9Very high96Very high5 Ų536 Ų362%0.02222%0.219CC..EExtended strand (participates in β ladder)trans-70.6118.3172.6175.3-112.8000109.4K27 G29 P32 M59 Q60 F77 F79 F188K27-F57 HydrophobicContact CG-CE1 4.47Å; G29-F57 VanDerWaalsContact O-CD1 3.24Å; G29-F57 WeakPolarHBondContact O-CD1 3.17Å; G29-F57 WeakPolarHBondContact O-CE1 3.36Å; P32-F57 HydrophobicContact CB-CD2 3.88Å; P32-F57 HydrophobicContact CB-CE2 4.06Å; P32-F57 HydrophobicContact CB-CG 4.19Å; P32-F57 HydrophobicContact CG-CB 3.81Å; P32-F57 HydrophobicContact CG-CD1 4.4Å; P32-F57 HydrophobicContact CG-CD2 3.69Å; P32-F57 HydrophobicContact CG-CE2 4.37Å; P32-F57 HydrophobicContact CG-CG 3.69Å; F57-M59 VanDerWaalsContact CE2-C 3.44Å; F57-M59 VanDerWaalsContact CE2-O 3.23Å; F57-M59 WeakPolarHBondContact CE2-O 3.47Å; F57-Q60 HydrophobicContact CE2-CB 3.98Å; F57-Q60 HydrophobicContact CE2-CG 4.48Å; F57-Q60 HydrophobicContact CZ-CB 3.75Å; F57-Q60 HydrophobicContact CZ-CG 3.79Å; F57-F77 AromaticContact CE2-CD1 3.98Å; F57-F77 HydrophobicContact CE2-CD1 3.98Å; F57-F79 HydrophobicContact CB-CD1 4.06Å; F57-F79 HydrophobicContact CB-CE1 3.84Å; F57-F79 HydrophobicContact CD2-CD1 4.33Å; F57-F79 AromaticContact CD2-CE1 3.8Å; F57-F79 HydrophobicContact CD2-CE1 3.8Å; F57-F79 HydrophobicContact CD2-CE2 4.46Å; F57-F79 AromaticContact CD2-CZ 3.84Å; F57-F79 HydrophobicContact CD2-CZ 3.84Å; F57-F79 HydrophobicContact CG-CE1 4.3Å; F57-F188 VanDerWaalsContact O-CD2 3.26Å; F57-F188 WeakPolarHBondContact O-CD2 3.21Å
58L97.9Very high95.6Very high0 Ų036.2 Ų36.20%022%0.221CC..EExtended strand (participates in β ladder)trans-89.3-57.1-179.4176.860.7000110.5G29 A56 V78 C80 F188 L300 L304 W315 L318G29-L58 PolarHBondContact N-O 2.89Å; A56-L58 PolarHBondContact O-N 2.91Å; L58-V78 HydrophobicContact CB-CB 4.5Å; L58-V78 HydrophobicContact CB-CG1 4.42Å; L58-V78 WeakPolarHBondContact CB-O 3.49Å; L58-V78 HydrophobicContact CD2-CG1 3.97Å; L58-V78 PolarHBondContact N-O 3.48Å; L58-C80 HydrophobicContact CD2-CB 4.47Å; L58-F188 HydrophobicContact CD1-CD2 4.42Å; L58-F188 HydrophobicContact CD1-CE2 4.24Å; L58-L300 HydrophobicContact CD1-CD2 4.1Å; L58-L300 HydrophobicContact CG-CD2 4.38Å; L58-L304 HydrophobicContact CD1-CD1 3.66Å; L58-L304 HydrophobicContact CD1-CD2 3.78Å; L58-L304 HydrophobicContact CD1-CG 4.37Å; L58-W315 HydrophobicContact CD1-CH2 4.2Å; L58-W315 HydrophobicContact CD2-CH2 4.07Å; L58-L318 HydrophobicContact CD2-CD1 4.43Å
59M98.6Very high95.3Very high0 Ų041.5 Ų41.50%025%0.249CC..EExtended strand (participates in β ladder)trans-162.5165.6-178.470.6-172.6-5100112.1K27 V28 F57 V61 V78 L193 L259 V296 L300K27-M59 CarbonylContact O-C 3.58Å; K27-M59 WeakPolarHBondContact O-CA 3.3Å; K27-M59 WeakPolarHBondContact O-CB 3.2Å; V28-M59 HydrophobicContact CG2-CB 3.91Å; V28-M59 HydrophobicContact CG2-CE 4.14Å; F57-M59 VanDerWaalsContact CE2-C 3.44Å; F57-M59 VanDerWaalsContact CE2-O 3.23Å; F57-M59 WeakPolarHBondContact CE2-O 3.47Å; M59-V61 HydrophobicContact CE-CG2 4.27Å; M59-V78 HydrophobicContact CG-CB 4Å; M59-V78 HydrophobicContact CG-CG2 4.05Å; M59-V78 PolarHBondContact N-O 2.9Å; M59-V78 PolarHBondContact O-N 2.83Å; M59-L193 HydrophobicContact CE-CD2 3.43Å; M59-L193 VanDerWaalsContact CE-CD2 3.43Å; M59-L259 HydrophobicContact CE-CD1 3.89Å; M59-V296 HydrophobicContact SD-CB 4.39Å; M59-V296 HydrophobicContact SD-CG1 3.93Å; M59-V296 HydrophobicContact SD-CG2 3.53Å; M59-V296 VanDerWaalsContact SD-CG2 3.53Å; M59-L300 HydrophobicContact SD-CD2 4.19Å
60Q98.3Very high95.1Very high1 Ų145.1 Ų45.11%0.00525%0.253CS..EExtended strand (participates in β ladder)trans-136148.6165.866.8-175.668.300111.2P25 S26 K27 A33 F57 T75 I76 F77P25-Q60 PolarHBondContact O-NE2 3.38Å; S26-Q60 CarbonylContact C-O 3.55Å; S26-Q60 WeakPolarHBondContact CA-O 3.22Å; K27-Q60 HydrophobicContact CD-CG 4.36Å; K27-Q60 HydrophobicContact CG-CG 3.59Å; K27-Q60 PolarHBondContact N-O 3.04Å; K27-Q60 PolarHBondContact O-N 2.84Å; A33-Q60 PolarHBondContact O-NE2 3.28Å; F57-Q60 HydrophobicContact CE2-CB 3.98Å; F57-Q60 HydrophobicContact CE2-CG 4.48Å; F57-Q60 HydrophobicContact CZ-CB 3.75Å; F57-Q60 HydrophobicContact CZ-CG 3.79Å; Q60-T75 HydrophobicContact CB-CG2 3.9Å; Q60-T75 HydrophobicContact CG-CG2 4.33Å; Q60-I76 CarbonylContact C-O 3.55Å; Q60-I76 WeakPolarHBondContact CA-O 3.27Å; Q60-I76 WeakPolarHBondContact CB-O 3.29Å; Q60-F77 HydrophobicContact CB-CD1 3.84Å; Q60-F77 HydrophobicContact CB-CE1 4.11Å; Q60-F77 HydrophobicContact CB-CG 4.37Å
61V98.6Very high94.9Very high4 Ų442.6 Ų42.62%0.02424%0.242CC..EExtended strand (participates in β ladder)trans-124.2122177.9-174.40000108.5M59 A63 T75 I76 L193 L259 Y261 F294M59-V61 HydrophobicContact CE-CG2 4.27Å; V61-A63 HydrophobicContact CG1-CB 4.45Å; V61-T75 WeakPolarHBondContact O-CA 3.48Å; V61-I76 PolarHBondContact N-O 2.92Å; V61-I76 PolarHBondContact O-N 2.73Å; V61-L193 HydrophobicContact CG2-CD2 4.01Å; V61-L259 HydrophobicContact CG1-CD2 4.43Å; V61-L259 HydrophobicContact CG2-CD1 4.09Å; V61-L259 HydrophobicContact CG2-CD2 4.28Å; V61-Y261 HydrophobicContact CG1-CD2 4.24Å; V61-Y261 HydrophobicContact CG1-CE2 4.41Å; V61-F294 HydrophobicContact CB-CE1 4.14Å; V61-F294 HydrophobicContact CB-CZ 4.48Å; V61-F294 HydrophobicContact CG2-CD1 4.43Å; V61-F294 HydrophobicContact CG2-CE1 3.98Å; V61-F294 HydrophobicContact CG2-CE2 4.27Å; V61-F294 HydrophobicContact CG2-CZ 3.88Å
62Y97.9Very high94.9Very high59 Ų5944.8 Ų44.823%0.23125%0.247CC..EExtended strand (participates in β ladder)trans-79.9115.4169.9-175-110.7000109.4F24 S26 P64 F72 H73 R74F24-Y62 HydrophobicContact CB-CD2 3.83Å; F24-Y62 HydrophobicContact CB-CE1 4.49Å; F24-Y62 HydrophobicContact CB-CE2 3.77Å; F24-Y62 HydrophobicContact CB-CG 4.21Å; F24-Y62 HydrophobicContact CD1-CE2 4.19Å; F24-Y62 HydrophobicContact CG-CE2 4.19Å; F24-Y62 WeakPolarHBondContact O-CB 2.88Å; S26-Y62 PolarHBondContact OG-N 3.38Å; Y62-P64 HydrophobicContact CD1-CG 4.39Å; Y62-P64 HydrophobicContact CE1-CB 4.47Å; Y62-P64 HydrophobicContact CE1-CG 3.9Å; Y62-F72 PolarHBondContact OH-O 2.86Å; Y62-H73 HydrophobicContact CE2-CB 4.1Å; Y62-H73 AromaticContact CE2-ND1 3.88Å; Y62-H73 AromaticContact CZ-ND1 3.75Å; Y62-H73 PolarHBondContact OH-ND1 3.41Å; Y62-R74 WeakPolarHBondContact CD2-O 3.47Å
63A96.6Very high94.9Very high3 Ų339.5 Ų39.53%0.02522%0.222CC..  trans-139.866.5-165.300000111V61 R74 I76 Y261V61-A63 HydrophobicContact CG1-CB 4.45Å; A63-R74 CarbonylContact C-O 3.59Å; A63-R74 PolarHBondContact N-O 3.37Å; A63-R74 WeakPolarHBondContact O-CB 3.28Å; A63-R74 VanDerWaalsContact O-CD 3.27Å; A63-R74 WeakPolarHBondContact O-CD 3.45Å; A63-R74 VanDerWaalsContact O-CG 3.29Å; A63-R74 WeakPolarHBondContact O-CG 3.46Å; A63-R74 PolarHBondContact O-NH1 3.36Å; A63-I76 HydrophobicContact CB-CD1 4.33Å; A63-Y261 HydrophobicContact CB-CE2 3.8Å; A63-Y261 WeakPolarHBondContact CB-OH 3.39Å
64P95.8Very high94.9Very high61 Ų6136.3 Ų36.340%0.39621%0.206SC..  trans-64.2148.717930.6-36.8000111.6Y62 S71 F72Y62-P64 HydrophobicContact CD1-CG 4.39Å; Y62-P64 HydrophobicContact CE1-CB 4.47Å; Y62-P64 HydrophobicContact CE1-CG 3.9Å; P64-S71 WeakPolarHBondContact CA-O 3.1Å; P64-F72 VanDerWaalsContact CB-O 3.26Å; P64-F72 WeakPolarHBondContact CB-O 3.4Å
65I94.3Very high95Very high30 Ų3035.8 Ų35.815%0.15420%0.203CC..  trans-108.7115175.9-59.6168.1000109.1G67 Q68 S71I65-G67 PolarHBondContact O-N 2.91Å; I65-Q68 HydrophobicContact CG2-CB 4.26Å; I65-Q68 PolarHBondContact O-N 2.86Å; I65-S71 WeakPolarHBondContact CB-OG 3.22Å; I65-S71 PolarHBondContact N-O 3.46Å
66T89.9Confident95.1Very high128 Ų12835.7 Ų35.779%0.78520%0.202SC*.THydrogen-bonded Turntrans-60.5131.3179-63.40000111Q68T66-Q68 VanDerWaalsContact C-N 3.34Å
67G87.4Confident95.2Very high89 Ų8935.7 Ų35.792%0.91820%0.202SC*.THydrogen-bonded Turntrans85.5-0.3176.600000115I65I65-G67 PolarHBondContact O-N 2.91Å
68Q88.9Confident95.3Very high63 Ų6335.5 Ų35.529%0.29420%0.201SC..  trans-115.7108.1174.6179.9174.526.300109.9I65 T66 R70 S71 D325 S326I65-Q68 HydrophobicContact CG2-CB 4.26Å; I65-Q68 PolarHBondContact O-N 2.86Å; T66-Q68 VanDerWaalsContact C-N 3.34Å; Q68-R70 VanDerWaalsContact C-N 3.33Å; Q68-R70 PolarHBondContact O-N 2.86Å; Q68-S71 WeakPolarHBondContact CB-OG 3.27Å; Q68-S71 WeakPolarHBondContact CG-OG 3.21Å; Q68-S71 PolarHBondContact O-N 2.96Å; Q68-S71 VanDerWaalsContact O-N 3.13Å; Q68-S71 PolarHBondContact O-OG 2.83Å; Q68-S71 PolarHBondContact OE1-OG 2.96Å; Q68-D325 PolarHBondContact NE2-O 3.09Å; Q68-S326 VanDerWaalsContact OE1-CB 3.32Å
69D90.1Very high95.3Very high110 Ų11035.5 Ų35.559%0.58820%0.201SC*.G310 helixtrans-56.5-44.5-171.8179.264.5000112.5S71 F72 P103D69-S71 PolarHBondContact O-N 2.84Å; D69-F72 WeakPolarHBondContact O-CB 3.49Å; D69-F72 PolarHBondContact O-N 3.33Å; D69-P103 VanDerWaalsContact O-CA 3.28Å; D69-P103 WeakPolarHBondContact O-CA 3.2Å
70R92Very high95.2Very high107 Ų10735.5 Ų35.540%0.40420%0.201SC..G310 helixtrans-66.1-22.1-178.3-76.9-70.3179.5179.8-3.4114.8Q68 Q101 L102 D328Q68-R70 VanDerWaalsContact C-N 3.33Å; Q68-R70 PolarHBondContact O-N 2.86Å; R70-Q101 WeakPolarHBondContact O-CB 3.43Å; R70-L102 CarbonylContact O-C 3.49Å; R70-L102 PolarHBondContact O-N 3.23Å; R70-D328 WeakPolarHBondContact CD-OD2 3.5Å; R70-D328 HydrophobicContact CG-CB 4.49Å; R70-D328 IonicContact CZ-OD2 3Å; R70-D328 IonicContact NE-OD2 2.82Å; R70-D328 PolarHBondContact NE-OD2 2.81Å; R70-D328 VanDerWaalsContact NE-OD2 3.09Å
71S93.5Very high95.1Very high0 Ų035.5 Ų35.50%020%0.201CC..G310 helixtrans-105.423.4179.653.90000111.8P64 I65 Q68 D69 H73P64-S71 WeakPolarHBondContact CA-O 3.1Å; I65-S71 WeakPolarHBondContact CB-OG 3.22Å; I65-S71 PolarHBondContact N-O 3.46Å; Q68-S71 WeakPolarHBondContact CB-OG 3.27Å; Q68-S71 WeakPolarHBondContact CG-OG 3.21Å; Q68-S71 PolarHBondContact O-N 2.96Å; Q68-S71 VanDerWaalsContact O-N 3.13Å; Q68-S71 PolarHBondContact O-OG 2.83Å; Q68-S71 PolarHBondContact OE1-OG 2.96Å; D69-S71 PolarHBondContact O-N 2.84Å; S71-H73 VanDerWaalsContact C-N 3.3Å
72F94.8Very high94.8Very high86 Ų8638 Ų3838%0.37721%0.212SC..SBendtrans-57.6-48.1174.9-174.5-76.7000110.4Y62 P64 D69 R104Y62-F72 PolarHBondContact OH-O 2.86Å; P64-F72 VanDerWaalsContact CB-O 3.26Å; P64-F72 WeakPolarHBondContact CB-O 3.4Å; D69-F72 WeakPolarHBondContact O-CB 3.49Å; D69-F72 PolarHBondContact O-N 3.33Å; F72-R104 HydrophobicContact CB-CB 4.21Å; F72-R104 HydrophobicContact CD1-CB 4.01Å; F72-R104 HydrophobicContact CD1-CG 4.4Å; F72-R104 HydrophobicContact CD2-CB 3.82Å; F72-R104 HydrophobicContact CD2-CG 4.38Å; F72-R104 HydrophobicContact CE1-CB 4.46Å; F72-R104 VanDerWaalsContact CE1-CD 3.4Å; F72-R104 HydrophobicContact CE1-CG 4.38Å; F72-R104 HydrophobicContact CE2-CB 4.22Å; F72-R104 HydrophobicContact CE2-CG 4.28Å; F72-R104 HydrophobicContact CG-CB 3.7Å; F72-R104 HydrophobicContact CG-CG 4.44Å; F72-R104 HydrophobicContact CZ-CG 4.3Å
73H95.3Very high94.5Very high3 Ų337 Ų371%0.01421%0.212CC..EExtended strand (participates in β ladder)trans-104.7121.7162.5-60.7-67.3000107.4F24 L35 Y62 S71 Q101 L102 R104F24-H73 AromaticContact CD1-ND1 3.65Å; F24-H73 HydrophobicContact CE1-CB 4.39Å; F24-H73 AromaticContact CE1-CE1 3.7Å; F24-H73 AromaticContact CE1-CG 3.78Å; F24-H73 AromaticContact CE1-ND1 3.46Å; F24-H73 WeakPolarHBondContact CE1-ND1 3.33Å; F24-H73 AromaticContact CE2-CE1 3.67Å; F24-H73 AromaticContact CZ-CE1 3.41Å; F24-H73 VanDerWaalsContact CZ-CE1 3.41Å; F24-H73 WeakPolarHBondContact CZ-CE1 3.37Å; F24-H73 AromaticContact CZ-ND1 3.69Å; F24-H73 AromaticContact CZ-NE2 3.84Å; L35-H73 HydrophobicContact CD1-CB 3.89Å; L35-H73 HydrophobicContact CD2-CB 4.15Å; Y62-H73 HydrophobicContact CE2-CB 4.1Å; Y62-H73 AromaticContact CE2-ND1 3.88Å; Y62-H73 AromaticContact CZ-ND1 3.75Å; Y62-H73 PolarHBondContact OH-ND1 3.41Å; S71-H73 VanDerWaalsContact C-N 3.3Å; H73-Q101 CarbonylContact O-C 3.35Å; H73-Q101 VanDerWaalsContact O-CA 3.22Å; H73-Q101 WeakPolarHBondContact O-CA 3.26Å; H73-L102 HydrophobicContact CB-CB 4.23Å; H73-L102 PolarHBondContact N-O 3.47Å; H73-L102 PolarHBondContact O-N 3.08Å; H73-R104 PolarHBondContact CE1-NH1 2.67Å; H73-R104 PolarHBondContact NE2-NH1 3.13Å
74R97.2Very high94.1Very high0 Ų038.4 Ų38.40%022%0.22CC..EExtended strand (participates in β ladder)trans-142125.3177.8170.5172.7179.9-78.54.9108.2Y62 A63 R99 S100 Q101 E293 T322 S326Y62-R74 WeakPolarHBondContact CD2-O 3.47Å; A63-R74 CarbonylContact C-O 3.59Å; A63-R74 PolarHBondContact N-O 3.37Å; A63-R74 WeakPolarHBondContact O-CB 3.28Å; A63-R74 VanDerWaalsContact O-CD 3.27Å; A63-R74 WeakPolarHBondContact O-CD 3.45Å; A63-R74 VanDerWaalsContact O-CG 3.29Å; A63-R74 WeakPolarHBondContact O-CG 3.46Å; A63-R74 PolarHBondContact O-NH1 3.36Å; R74-R99 HydrophobicContact CG-CG 4.4Å; R74-S100 WeakPolarHBondContact CA-O 3.38Å; R74-Q101 HydrophobicContact CB-CG 4.14Å; R74-Q101 HydrophobicContact CG-CG 3.91Å; R74-E293 IonicContact CZ-OE1 3.49Å; R74-E293 VanDerWaalsContact CZ-OE1 3.26Å; R74-E293 IonicContact CZ-OE2 3.21Å; R74-E293 IonicContact NH1-OE1 3.93Å; R74-E293 PolarHBondContact NH1-OE1 3.24Å; R74-E293 IonicContact NH2-OE1 3.33Å; R74-E293 PolarHBondContact NH2-OE1 3.26Å; R74-E293 IonicContact NH2-OE2 2.99Å; R74-E293 PolarHBondContact NH2-OE2 3.43Å; R74-T322 PolarHBondContact NH2-OG1 3.34Å; R74-S326 PolarHBondContact NE-OG 2.95Å
75T98Very high93.8Very high1 Ų142.5 Ų42.51%0.00624%0.239CC..EExtended strand (participates in β ladder)trans-130.6135.3-178.8-53.10000109.4Q60 V61 F77 R99 S100Q60-T75 HydrophobicContact CB-CG2 3.9Å; Q60-T75 HydrophobicContact CG-CG2 4.33Å; V61-T75 WeakPolarHBondContact O-CA 3.48Å; T75-F77 HydrophobicContact CG2-CD2 4.12Å; T75-F77 HydrophobicContact CG2-CE1 3.99Å; T75-F77 HydrophobicContact CG2-CE2 3.51Å; T75-F77 HydrophobicContact CG2-CZ 3.43Å; T75-F77 VanDerWaalsContact CG2-CZ 3.43Å; T75-R99 WeakPolarHBondContact O-CA 3.41Å; T75-S100 PolarHBondContact N-O 2.99Å; T75-S100 PolarHBondContact O-N 3.19Å
76I98.6Very high93.8Very high0 Ų041.3 Ų41.30%023%0.233CC..EExtended strand (participates in β ladder)trans-108.8128.3175.2-60.1160.4000107.7Q60 V61 A63 V97 F98 R99 E293 F294 V320 T322Q60-I76 CarbonylContact C-O 3.55Å; Q60-I76 WeakPolarHBondContact CA-O 3.27Å; Q60-I76 WeakPolarHBondContact CB-O 3.29Å; V61-I76 PolarHBondContact N-O 2.92Å; V61-I76 PolarHBondContact O-N 2.73Å; A63-I76 HydrophobicContact CB-CD1 4.33Å; I76-V97 HydrophobicContact CG2-CG1 3.56Å; I76-F98 CarbonylContact C-O 3.58Å; I76-F98 WeakPolarHBondContact CA-O 3.22Å; I76-R99 HydrophobicContact CG1-CB 4.45Å; I76-R99 HydrophobicContact CG1-CG 4.37Å; I76-E293 HydrophobicContact CD1-CG 3.6Å; I76-F294 HydrophobicContact CB-CE1 3.94Å; I76-F294 HydrophobicContact CB-CZ 4.41Å; I76-F294 HydrophobicContact CD1-CD1 4.24Å; I76-F294 HydrophobicContact CD1-CE1 3.72Å; I76-F294 HydrophobicContact CG1-CE1 4.47Å; I76-F294 HydrophobicContact CG2-CE1 3.74Å; I76-F294 HydrophobicContact CG2-CZ 3.89Å; I76-V320 HydrophobicContact CG2-CG1 4.18Å; I76-T322 HydrophobicContact CD1-CG2 3.7Å; I76-T322 HydrophobicContact CG1-CG2 4.24Å
77F98.8Very high93.9Very high0 Ų036.5 Ų36.50%020%0.201CC..EExtended strand (participates in β ladder)trans-112.6134.7-176.9-59.2-98.8000109.1P32 A33 W34 L35 F57 Q60 T75 F79 V97 F98 Y333P32-F77 HydrophobicContact CB-CD1 4.37Å; P32-F77 HydrophobicContact CB-CE1 4.47Å; A33-F77 WeakPolarHBondContact O-CE1 3.5Å; W34-F77 HydrophobicContact CE3-CD1 4.23Å; W34-F77 HydrophobicContact CE3-CE1 4.03Å; W34-F77 HydrophobicContact CE3-CZ 4.3Å; W34-F77 HydrophobicContact CZ3-CD1 4.22Å; W34-F77 HydrophobicContact CZ3-CE1 4.48Å; W34-F77 HydrophobicContact CZ3-CG 4.38Å; L35-F77 HydrophobicContact CB-CZ 4.3Å; F57-F77 AromaticContact CE2-CD1 3.98Å; F57-F77 HydrophobicContact CE2-CD1 3.98Å; Q60-F77 HydrophobicContact CB-CD1 3.84Å; Q60-F77 HydrophobicContact CB-CE1 4.11Å; Q60-F77 HydrophobicContact CB-CG 4.37Å; T75-F77 HydrophobicContact CG2-CD2 4.12Å; T75-F77 HydrophobicContact CG2-CE1 3.99Å; T75-F77 HydrophobicContact CG2-CE2 3.51Å; T75-F77 HydrophobicContact CG2-CZ 3.43Å; T75-F77 VanDerWaalsContact CG2-CZ 3.43Å; F77-F79 HydrophobicContact CB-CD2 4.44Å; F77-F79 HydrophobicContact CB-CE2 3.65Å; F77-F79 HydrophobicContact CB-CZ 4.35Å; F77-V97 CarbonylContact O-C 3.49Å; F77-V97 VanDerWaalsContact O-CA 3.25Å; F77-V97 WeakPolarHBondContact O-CA 3.36Å; F77-V97 WeakPolarHBondContact O-CG1 3.23Å; F77-F98 PolarHBondContact N-O 3.36Å; F77-F98 PolarHBondContact O-N 3.13Å; F77-Y333 HydrophobicContact CD2-CD1 4.29Å; F77-Y333 AromaticContact CD2-CE1 3.93Å; F77-Y333 HydrophobicContact CD2-CE1 3.93Å; F77-Y333 HydrophobicContact CE2-CD1 4.35Å; F77-Y333 AromaticContact CE2-CE1 3.61Å; F77-Y333 HydrophobicContact CE2-CE1 3.61Å; F77-Y333 HydrophobicContact CZ-CE1 4.14Å
78V98.8Very high94.1Very high0 Ų034.6 Ų34.60%017%0.174CC..EExtended strand (participates in β ladder)trans-118.8133.7176.8-171.80000108.8L58 M59 K96 V97 F294 V320 I338L58-V78 HydrophobicContact CB-CB 4.5Å; L58-V78 HydrophobicContact CB-CG1 4.42Å; L58-V78 WeakPolarHBondContact CB-O 3.49Å; L58-V78 HydrophobicContact CD2-CG1 3.97Å; L58-V78 PolarHBondContact N-O 3.48Å; M59-V78 HydrophobicContact CG-CB 4Å; M59-V78 HydrophobicContact CG-CG2 4.05Å; M59-V78 PolarHBondContact N-O 2.9Å; M59-V78 PolarHBondContact O-N 2.83Å; V78-K96 WeakPolarHBondContact CA-O 3.45Å; V78-V97 HydrophobicContact CG1-CG2 4.21Å; V78-V97 HydrophobicContact CG2-CG2 4.16Å; V78-F294 HydrophobicContact CG2-CE2 4.4Å; V78-F294 HydrophobicContact CG2-CZ 4.12Å; V78-V320 HydrophobicContact CG2-CG2 4.46Å; V78-I338 HydrophobicContact CG1-CD1 3.95Å
79F98.5Very high94.2Very high0 Ų037.5 Ų37.50%018%0.182CC..EExtended strand (participates in β ladder)trans-126148.6176.2-60.5-101.5000109.9P32 W34 L46 T55 A56 F57 F77 L95 K96 F98P32-F79 HydrophobicContact CB-CZ 4.44Å; P32-F79 HydrophobicContact CG-CE1 3.85Å; P32-F79 HydrophobicContact CG-CZ 3.96Å; W34-F79 HydrophobicContact CH2-CE1 4.24Å; W34-F79 HydrophobicContact CH2-CE2 4.11Å; W34-F79 AromaticContact CH2-CZ 3.39Å; W34-F79 HydrophobicContact CH2-CZ 3.39Å; W34-F79 HydrophobicContact CZ2-CZ 4.06Å; W34-F79 HydrophobicContact CZ3-CE2 4.45Å; W34-F79 HydrophobicContact CZ3-CZ 4.01Å; L46-F79 HydrophobicContact CD2-CD1 4.01Å; L46-F79 HydrophobicContact CD2-CD2 3.8Å; L46-F79 HydrophobicContact CD2-CE1 4.09Å; L46-F79 HydrophobicContact CD2-CE2 3.88Å; L46-F79 HydrophobicContact CD2-CG 3.89Å; L46-F79 HydrophobicContact CD2-CZ 4.05Å; T55-F79 WeakPolarHBondContact OG1-CB 3.44Å; A56-F79 CarbonylContact O-C 3.59Å; A56-F79 WeakPolarHBondContact O-CA 3.5Å; A56-F79 WeakPolarHBondContact O-CB 3.46Å; F57-F79 HydrophobicContact CB-CD1 4.06Å; F57-F79 HydrophobicContact CB-CE1 3.84Å; F57-F79 HydrophobicContact CD2-CD1 4.33Å; F57-F79 AromaticContact CD2-CE1 3.8Å; F57-F79 HydrophobicContact CD2-CE1 3.8Å; F57-F79 HydrophobicContact CD2-CE2 4.46Å; F57-F79 AromaticContact CD2-CZ 3.84Å; F57-F79 HydrophobicContact CD2-CZ 3.84Å; F57-F79 HydrophobicContact CG-CE1 4.3Å; F77-F79 HydrophobicContact CB-CD2 4.44Å; F77-F79 HydrophobicContact CB-CE2 3.65Å; F77-F79 HydrophobicContact CB-CZ 4.35Å; F79-L95 CarbonylContact O-C 3.52Å; F79-L95 WeakPolarHBondContact O-CA 3.23Å; F79-K96 HydrophobicContact CB-CB 4.24Å; F79-K96 PolarHBondContact N-O 3.42Å; F79-K96 PolarHBondContact O-N 3.23Å; F79-F98 HydrophobicContact CD2-CD2 4.15Å; F79-F98 HydrophobicContact CD2-CE2 4.5Å; F79-F98 HydrophobicContact CE2-CD2 4.14Å
80C97.1Very high94.4Very high0 Ų033.9 Ų33.90%016%0.163CC..EExtended strand (participates in β ladder)trans-137.8152.3179.371.70000112.1T55 A56 L58 Y87 C94 L95 F188T55-C80 CarbonylContact C-O 3.58Å; T55-C80 WeakPolarHBondContact CA-O 3.42Å; T55-C80 WeakPolarHBondContact CB-O 3.37Å; A56-C80 PolarHBondContact N-O 2.87Å; A56-C80 PolarHBondContact O-N 2.67Å; L58-C80 HydrophobicContact CD2-CB 4.47Å; C80-Y87 WeakPolarHBondContact CB-OH 3.31Å; C80-C94 CarbonylContact C-O 3.52Å; C80-L95 HydrophobicContact CB-CD2 3.49Å; C80-L95 VanDerWaalsContact CB-CD2 3.49Å; C80-F188 VanDerWaalsContact SG-CE2 3.58Å
81C95.4Very high94.4Very high1 Ų129.9 Ų29.91%0.00715%0.149CC..  trans-73145.9172.4-168.10000110.3C48 C51 T83 C86 Y87 C94C48-C81 HydrophobicContact CB-CB 3.98Å; C48-C81 VanDerWaalsContact SG-SG 3.63Å; C51-C81 PolarHBondContact SG-SG 3.12Å; C81-T83 VanDerWaalsContact SG-CB 3.6Å; C81-T83 PolarHBondContact SG-N 3.37Å; C81-T83 VanDerWaalsContact SG-N 3.38Å; C81-C86 HydrophobicContact CB-CB 4.27Å; C81-Y87 WeakPolarHBondContact O-CE2 3.43Å; C81-Y87 VanDerWaalsContact O-CZ 3.32Å; C81-Y87 PolarHBondContact O-OH 2.9Å; C81-C94 HydrophobicContact CB-CB 3.85Å; C81-C94 PolarHBondContact N-O 3.35Å
82K91.8Very high94.5Very high58 Ų5831 Ų3125%0.25216%0.157SC..  trans-96.65.4171.4-63.1-169.174171.20113.6A56 P185 F186 F188 I313A56-K82 HydrophobicContact CB-CD 3.87Å; A56-K82 HydrophobicContact CB-CG 3.86Å; K82-P185 PolarHBondContact NZ-O 3.21Å; K82-F186 HydrophobicContact CD-CD2 4.34Å; K82-F186 WeakPolarHBondContact CD-O 3.43Å; K82-F186 PolarHBondContact NZ-O 2.95Å; K82-F188 HydrophobicContact CD-CE1 4.43Å; K82-F188 HydrophobicContact CD-CZ 4.2Å; K82-F188 HydrophobicContact CG-CZ 4.08Å; K82-I313 HydrophobicContact CG-CD1 4.4Å
83T91.3Very high94.6Very high38 Ų3834 Ų3423%0.23317%0.166CC..  trans-88.1118.8178.1-55.10000110.1C81 D85 C86 Y87C81-T83 VanDerWaalsContact SG-CB 3.6Å; C81-T83 PolarHBondContact SG-N 3.37Å; C81-T83 VanDerWaalsContact SG-N 3.38Å; T83-D85 HydrophobicContact CG2-CB 4.49Å; T83-D85 PolarHBondContact O-N 2.84Å; T83-C86 VanDerWaalsContact O-CB 3.3Å; T83-C86 WeakPolarHBondContact O-CB 3.27Å; T83-C86 PolarHBondContact O-N 2.93Å; T83-C86 VanDerWaalsContact O-N 3.11Å; T83-Y87 WeakPolarHBondContact O-CD2 3.4Å
84P88.6Confident94.7Very high31 Ų3133.9 Ų33.920%0.20117%0.166CC..G310 helixtrans-51.1-49.5-179.7-27.131.3000114.1C86 Y87 D310 S312P84-C86 PolarHBondContact O-N 3.09Å; P84-Y87 WeakPolarHBondContact O-CB 3.12Å; P84-Y87 PolarHBondContact O-N 3.3Å; P84-D310 WeakPolarHBondContact CG-O 3.41Å; P84-S312 WeakPolarHBondContact CB-OG 3.04Å
85D90.5Very high94.7Very high148 Ų14834.2 Ų34.279%0.79117%0.167SC*.G310 helixtrans-62-12.6-175.4-58.9-18.8000113.1T83 Y87T83-D85 HydrophobicContact CG2-CB 4.49Å; T83-D85 PolarHBondContact O-N 2.84Å; D85-Y87 VanDerWaalsContact C-N 3.34Å
86C93.6Very high94.7Very high4 Ų436.8 Ų36.83%0.02718%0.178CC..G310 helixtrans-80.1-14174.4-65.20000113.2K50 C81 T83 P84 S88 C94K50-C86 HydrophobicContact CB-CB 4.37Å; K50-C86 HydrophobicContact CD-CB 4.04Å; K50-C86 VanDerWaalsContact CD-O 3.26Å; K50-C86 WeakPolarHBondContact CD-O 3.47Å; K50-C86 WeakPolarHBondContact CE-O 3.17Å; K50-C86 PolarHBondContact NZ-O 2.91Å; C81-C86 HydrophobicContact CB-CB 4.27Å; T83-C86 VanDerWaalsContact O-CB 3.3Å; T83-C86 WeakPolarHBondContact O-CB 3.27Å; T83-C86 PolarHBondContact O-N 2.93Å; T83-C86 VanDerWaalsContact O-N 3.11Å; P84-C86 PolarHBondContact O-N 3.09Å; C86-S88 VanDerWaalsContact C-N 3.32Å; C86-S88 PolarHBondContact O-N 2.66Å; C86-C94 HydrophobicContact CB-CB 3.79Å
87Y92.1Very high94.7Very high27 Ų2736.9 Ų36.911%0.10618%0.179CC..  trans-91.358.4-180-70.2-95.1000111.9C80 C81 T83 P84 D85 I313 D314 W315C80-Y87 WeakPolarHBondContact CB-OH 3.31Å; C81-Y87 WeakPolarHBondContact O-CE2 3.43Å; C81-Y87 VanDerWaalsContact O-CZ 3.32Å; C81-Y87 PolarHBondContact O-OH 2.9Å; T83-Y87 WeakPolarHBondContact O-CD2 3.4Å; P84-Y87 WeakPolarHBondContact O-CB 3.12Å; P84-Y87 PolarHBondContact O-N 3.3Å; D85-Y87 VanDerWaalsContact C-N 3.34Å; Y87-I313 HydrophobicContact CE1-CG2 3.8Å; Y87-I313 HydrophobicContact CE2-CB 4.31Å; Y87-I313 HydrophobicContact CE2-CG1 3.83Å; Y87-I313 HydrophobicContact CE2-CG2 4.31Å; Y87-D314 WeakPolarHBondContact CD1-O 3.34Å; Y87-W315 HydrophobicContact CE1-CE3 4.4Å
88S91.8Very high94.7Very high50 Ų5037 Ų3735%0.3518%0.18SC..  trans-68.9153.2167.971.70000110.9K50 C86 N90 D91K50-S88 PolarHBondContact NZ-OG 2.98Å; C86-S88 VanDerWaalsContact C-N 3.32Å; C86-S88 PolarHBondContact O-N 2.66Å; S88-N90 PolarHBondContact O-N 3.2Å; S88-D91 PolarHBondContact O-N 2.71Å; S88-D91 WeakPolarHBondContact OG-CB 3.47Å; S88-D91 PolarHBondContact OG-OD2 3.1Å
89R91.6Very high94.6Very high123 Ų12337 Ų3746%0.46418%0.18SC..THydrogen-bonded Turntrans-51.7129.3179.9-169.6170.8178.4-160.7-8.2111.7D91 E273 D342R89-D91 PolarHBondContact O-N 3.35Å; R89-E273 IonicContact NH2-OE2 2.99Å; R89-E273 PolarHBondContact NH2-OE2 2.89Å; R89-D342 VanDerWaalsContact CA-OD2 3.25Å; R89-D342 WeakPolarHBondContact CA-OD2 3.21Å; R89-D342 HydrophobicContact CG-CB 4.4Å
90N92.4Very high94.6Very high35 Ų3537 Ų3719%0.18718%0.18CC..THydrogen-bonded Turntrans56.235.5170-73.9-20.6000113.6S88 H274 Q341 D342S88-N90 PolarHBondContact O-N 3.2Å; N90-H274 HydrophobicContact CB-CB 4.41Å; N90-H274 WeakPolarHBondContact CB-CD2 3.45Å; N90-H274 WeakPolarHBondContact CB-NE2 3.49Å; N90-H274 VanDerWaalsContact CG-CG 3.41Å; N90-H274 WeakPolarHBondContact ND2-CB 3.33Å; N90-H274 PolarHBondContact O-CE1 2.71Å; N90-H274 PolarHBondContact O-NE2 3.36Å; N90-H274 PolarHBondContact OD1-CD2 3.21Å; N90-Q341 WeakPolarHBondContact OD1-CA 3.45Å; N90-D342 PolarHBondContact N-OD2 3.43Å; N90-D342 PolarHBondContact OD1-N 2.96Å
91D93.6Very high94.5Very high23 Ų2337.7 Ų37.712%0.12318%0.183CC..  trans-126.9119.9-177.9-172.7-17.1000111.5K50 S88 R89 R93 K340K50-D91 VanDerWaalsContact CE-CG 3.4Å; K50-D91 WeakPolarHBondContact CE-OD2 3.33Å; K50-D91 VanDerWaalsContact NZ-CG 3.3Å; K50-D91 IonicContact NZ-OD1 3.1Å; K50-D91 IonicContact NZ-OD2 3.88Å; K50-D91 PolarHBondContact NZ-OD2 2.72Å; S88-D91 PolarHBondContact O-N 2.71Å; S88-D91 WeakPolarHBondContact OG-CB 3.47Å; S88-D91 PolarHBondContact OG-OD2 3.1Å; R89-D91 PolarHBondContact O-N 3.35Å; D91-R93 VanDerWaalsContact OD1-CB 3.27Å; D91-R93 WeakPolarHBondContact OD1-CB 3.38Å; D91-R93 WeakPolarHBondContact OD1-CG 3.32Å; D91-R93 PolarHBondContact OD1-N 2.54Å; D91-R93 IonicContact OD1-NE 3.73Å; D91-R93 PolarHBondContact OD1-NE 3.44Å; D91-R93 VanDerWaalsContact OD1-NE 3.09Å; D91-R93 IonicContact OD2-CZ 2.75Å; D91-R93 IonicContact OD2-NE 3.09Å; D91-R93 PolarHBondContact OD2-NE 2.88Å; D91-R93 IonicContact OD2-NH2 2.63Å; D91-R93 PolarHBondContact OD2-NH2 3.48Å; D91-K340 WeakPolarHBondContact O-CD 2.98Å
92S95.5Very high94.6Very high24 Ų2437.7 Ų37.717%0.16818%0.182CC..  trans-952-174.7-51.30000113.8C94 L95 I338 K340S92-C94 PolarHBondContact O-N 3.19Å; S92-C94 VanDerWaalsContact O-N 3.11Å; S92-L95 WeakPolarHBondContact O-CB 3.45Å; S92-L95 PolarHBondContact O-N 3.18Å; S92-I338 WeakPolarHBondContact CB-O 3.42Å; S92-I338 PolarHBondContact OG-O 2.88Å; S92-K340 WeakPolarHBondContact OG-CB 2.9Å; S92-K340 PolarHBondContact OG-N 3.14Å
93R96.4Very high94.7Very high149 Ų14935.5 Ų35.556%0.56217%0.174SC*.THydrogen-bonded Turntrans-63.6-19.3-174.8-71.5179.1-69.3174.7-3.4114.4G49 K50 D91 L95G49-R93 WeakPolarHBondContact CA-O 3.4Å; G49-R93 PolarHBondContact N-O 2.85Å; K50-R93 HydrophobicContact CG-CB 4.17Å; D91-R93 VanDerWaalsContact OD1-CB 3.27Å; D91-R93 WeakPolarHBondContact OD1-CB 3.38Å; D91-R93 WeakPolarHBondContact OD1-CG 3.32Å; D91-R93 PolarHBondContact OD1-N 2.54Å; D91-R93 IonicContact OD1-NE 3.73Å; D91-R93 PolarHBondContact OD1-NE 3.44Å; D91-R93 VanDerWaalsContact OD1-NE 3.09Å; D91-R93 IonicContact OD2-CZ 2.75Å; D91-R93 IonicContact OD2-NE 3.09Å; D91-R93 PolarHBondContact OD2-NE 2.88Å; D91-R93 IonicContact OD2-NH2 2.63Å; D91-R93 PolarHBondContact OD2-NH2 3.48Å; R93-L95 VanDerWaalsContact C-N 3.28Å
94C96.3Very high94.8Very high0 Ų035.8 Ų35.80%017%0.171CC..THydrogen-bonded Turntrans-83.4-3.3174.665.90000113.6C80 C81 C86 S92C80-C94 CarbonylContact C-O 3.52Å; C81-C94 HydrophobicContact CB-CB 3.85Å; C81-C94 PolarHBondContact N-O 3.35Å; C86-C94 HydrophobicContact CB-CB 3.79Å; S92-C94 PolarHBondContact O-N 3.19Å; S92-C94 VanDerWaalsContact O-N 3.11Å
95L97.9Very high95.1Very high6 Ų643.8 Ų43.83%0.03120%0.197CC..EExtended strand (participates in β ladder)trans-111.4151.1-179.5-57.8165.5000110.1F79 C80 S92 R93 L318 I338 K340F79-L95 CarbonylContact O-C 3.52Å; F79-L95 WeakPolarHBondContact O-CA 3.23Å; C80-L95 HydrophobicContact CB-CD2 3.49Å; C80-L95 VanDerWaalsContact CB-CD2 3.49Å; S92-L95 WeakPolarHBondContact O-CB 3.45Å; S92-L95 PolarHBondContact O-N 3.18Å; R93-L95 VanDerWaalsContact C-N 3.28Å; L95-L318 HydrophobicContact CD1-CD1 4.22Å; L95-L318 HydrophobicContact CD1-CD2 3.66Å; L95-L318 HydrophobicContact CD2-CD1 4.37Å; L95-I338 HydrophobicContact CB-CD1 4.17Å; L95-I338 HydrophobicContact CB-CG2 3.73Å; L95-I338 HydrophobicContact CD1-CD1 3.94Å; L95-I338 HydrophobicContact CD1-CG1 4.21Å; L95-I338 HydrophobicContact CD1-CG2 4.45Å; L95-K340 HydrophobicContact CD1-CB 4.12Å; L95-K340 HydrophobicContact CD1-CD 4.34Å
96K98.4Very high95.2Very high56 Ų5638 Ų3824%0.24317%0.167CC..EExtended strand (participates in β ladder)trans-136.7142.5173.2-56.5-71-178.81690109.7E47 T55 V78 F79 F98E47-K96 WeakPolarHBondContact O-CE 3.44Å; E47-K96 PolarHBondContact O-NZ 3.49Å; T55-K96 HydrophobicContact CG2-CG 4.35Å; V78-K96 WeakPolarHBondContact CA-O 3.45Å; F79-K96 HydrophobicContact CB-CB 4.24Å; F79-K96 PolarHBondContact N-O 3.42Å; F79-K96 PolarHBondContact O-N 3.23Å; K96-F98 HydrophobicContact CB-CD2 4.48Å; K96-F98 HydrophobicContact CB-CE2 3.77Å
97V98.5Very high95Very high1 Ų144.9 Ų44.91%0.00620%0.203CC..EExtended strand (participates in β ladder)trans-129.8136.4173.4-1760000110.2I76 F77 V78 V320 E336 I338I76-V97 HydrophobicContact CG2-CG1 3.56Å; F77-V97 CarbonylContact O-C 3.49Å; F77-V97 VanDerWaalsContact O-CA 3.25Å; F77-V97 WeakPolarHBondContact O-CA 3.36Å; F77-V97 WeakPolarHBondContact O-CG1 3.23Å; V78-V97 HydrophobicContact CG1-CG2 4.21Å; V78-V97 HydrophobicContact CG2-CG2 4.16Å; V97-V320 HydrophobicContact CG1-CG1 3.84Å; V97-V320 HydrophobicContact CG2-CG2 4.35Å; V97-E336 HydrophobicContact CB-CB 4.24Å; V97-E336 HydrophobicContact CG1-CB 3.86Å; V97-E336 PolarHBondContact O-N 2.89Å; V97-I338 HydrophobicContact CG2-CB 3.61Å; V97-I338 HydrophobicContact CG2-CD1 3.74Å; V97-I338 HydrophobicContact CG2-CG1 4.23Å; V97-I338 HydrophobicContact CG2-CG2 3.94Å
98F98.4Very high94.8Very high4 Ų445 Ų452%0.01820%0.204CC..EExtended strand (participates in β ladder)trans-130.7147.7175.4-63.7-88.2000110.6P41 E45 L46 I76 F77 F79 K96 Y333 S334P41-F98 HydrophobicContact CB-CE1 4.2Å; P41-F98 HydrophobicContact CB-CZ 4.22Å; P41-F98 HydrophobicContact CG-CD1 3.88Å; P41-F98 HydrophobicContact CG-CD2 4.44Å; P41-F98 HydrophobicContact CG-CE1 4.05Å; P41-F98 HydrophobicContact CG-CG 4.08Å; P41-F98 HydrophobicContact CG-CZ 4.42Å; E45-F98 HydrophobicContact CB-CE1 4.33Å; E45-F98 HydrophobicContact CB-CZ 3.99Å; L46-F98 HydrophobicContact CD2-CD2 4.16Å; L46-F98 HydrophobicContact CD2-CE2 3.54Å; L46-F98 HydrophobicContact CD2-CZ 4.27Å; I76-F98 CarbonylContact C-O 3.58Å; I76-F98 WeakPolarHBondContact CA-O 3.22Å; F77-F98 PolarHBondContact N-O 3.36Å; F77-F98 PolarHBondContact O-N 3.13Å; F79-F98 HydrophobicContact CD2-CD2 4.15Å; F79-F98 HydrophobicContact CD2-CE2 4.5Å; F79-F98 HydrophobicContact CE2-CD2 4.14Å; K96-F98 HydrophobicContact CB-CD2 4.48Å; K96-F98 HydrophobicContact CB-CE2 3.77Å; F98-Y333 HydrophobicContact CB-CD1 4.18Å; F98-S334 CarbonylContact C-O 3.26Å; F98-S334 VanDerWaalsContact CA-O 3.27Å; F98-S334 WeakPolarHBondContact CA-O 3.3Å
99R97.9Very high94.7Very high0 Ų043.4 Ų43.40%019%0.19CC..EExtended strand (participates in β ladder)trans-119.2131.3172.5175.6-161.760.8146.83.9109R74 T75 I76 Q101 S326 C327 Y333 S334 E336R74-R99 HydrophobicContact CG-CG 4.4Å; T75-R99 WeakPolarHBondContact O-CA 3.41Å; I76-R99 HydrophobicContact CG1-CB 4.45Å; I76-R99 HydrophobicContact CG1-CG 4.37Å; R99-Q101 HydrophobicContact CG-CG 4.11Å; R99-Q101 VanDerWaalsContact CZ-NE2 3.3Å; R99-S326 PolarHBondContact NH1-O 3.48Å; R99-S326 PolarHBondContact NH1-OG 2.89Å; R99-C327 VanDerWaalsContact NH1-N 3.19Å; R99-C327 PolarHBondContact NH1-O 3.23Å; R99-C327 PolarHBondContact NH2-O 3.44Å; R99-C327 PolarHBondContact NH2-SG 3.1Å; R99-Y333 WeakPolarHBondContact O-CA 3.42Å; R99-S334 PolarHBondContact N-O 3.3Å; R99-S334 PolarHBondContact NH2-OG 3.07Å; R99-S334 PolarHBondContact O-N 2.67Å; R99-E336 HydrophobicContact CB-CG 3.63Å; R99-E336 WeakPolarHBondContact CD-OE1 3.13Å; R99-E336 IonicContact CZ-OE1 2.69Å; R99-E336 IonicContact NE-OE1 3.81Å; R99-E336 PolarHBondContact NE-OE1 2.65Å; R99-E336 IonicContact NH2-OE1 3.89Å
100S97.3Very high94.5Very high0 Ų042.2 Ų42.20%020%0.198CC..EExtended strand (participates in β ladder)trans-118.7146.4170.5-1700000109.5L35 R74 T75 Y333L35-S100 WeakPolarHBondContact CD2-O 3.24Å; R74-S100 WeakPolarHBondContact CA-O 3.38Å; T75-S100 PolarHBondContact N-O 2.99Å; T75-S100 PolarHBondContact O-N 3.19Å; S100-Y333 VanDerWaalsContact CB-CE1 3.46Å
101Q96.2Very high94.3Very high14 Ų1446.4 Ų46.47%0.06521%0.213CC..EExtended strand (participates in β ladder)trans-142.6142.9-177.8-56.3-174.6101.300110.5R70 H73 R74 R99 S326 C327R70-Q101 WeakPolarHBondContact O-CB 3.43Å; H73-Q101 CarbonylContact O-C 3.35Å; H73-Q101 VanDerWaalsContact O-CA 3.22Å; H73-Q101 WeakPolarHBondContact O-CA 3.26Å; R74-Q101 HydrophobicContact CB-CG 4.14Å; R74-Q101 HydrophobicContact CG-CG 3.91Å; R99-Q101 HydrophobicContact CG-CG 4.11Å; R99-Q101 VanDerWaalsContact CZ-NE2 3.3Å; Q101-S326 VanDerWaalsContact CD-OG 3.32Å; Q101-S326 PolarHBondContact NE2-O 2.87Å; Q101-S326 PolarHBondContact OE1-OG 3.16Å; Q101-C327 PolarHBondContact NE2-O 3.05Å; Q101-C327 VanDerWaalsContact NE2-O 3.11Å
102L95.8Very high94Very high0 Ų050.7 Ų50.70%024%0.236CC..EExtended strand (participates in β ladder)trans-138.3142.2173.7-61.2171.4000110L35 R70 H73 N106 F108 Y109L35-L102 HydrophobicContact CD1-CD1 3.94Å; L35-L102 HydrophobicContact CD2-CD1 4.38Å; L35-L102 HydrophobicContact CD2-CG 4.23Å; L35-L102 HydrophobicContact CG-CD1 3.71Å; L35-L102 HydrophobicContact CG-CG 4.06Å; R70-L102 CarbonylContact O-C 3.49Å; R70-L102 PolarHBondContact O-N 3.23Å; H73-L102 HydrophobicContact CB-CB 4.23Å; H73-L102 PolarHBondContact N-O 3.47Å; H73-L102 PolarHBondContact O-N 3.08Å; L102-N106 HydrophobicContact CB-CB 4.28Å; L102-F108 HydrophobicContact CD1-CD2 3.62Å; L102-F108 HydrophobicContact CD1-CE2 4.28Å; L102-F108 HydrophobicContact CD2-CD2 3.81Å; L102-F108 HydrophobicContact CD2-CE2 3.66Å; L102-F108 HydrophobicContact CG-CD2 4.38Å; L102-Y109 HydrophobicContact CD1-CD2 3.97Å; L102-Y109 HydrophobicContact CD1-CE2 3.73Å
103P95.5Very high93.3Very high13 Ų1354.1 Ų54.18%0.08426%0.257CS..  trans-66.3164.8167.130.5-34.9000111.5D69 R105 N106D69-P103 VanDerWaalsContact O-CA 3.28Å; D69-P103 WeakPolarHBondContact O-CA 3.2Å; P103-R105 VanDerWaalsContact C-N 3.27Å; P103-R105 WeakPolarHBondContact CG-O 2.9Å; P103-R105 PolarHBondContact O-N 2.99Å; P103-N106 PolarHBondContact O-ND2 3.41Å
104R93.4Very high92.3Very high43 Ų4349.5 Ų49.516%0.16225%0.247CC..SBendtrans-56.2-43.6178.3179.551.1170.6-177.4-6112F72 H73 N106 Y111F72-R104 HydrophobicContact CB-CB 4.21Å; F72-R104 HydrophobicContact CD1-CB 4.01Å; F72-R104 HydrophobicContact CD1-CG 4.4Å; F72-R104 HydrophobicContact CD2-CB 3.82Å; F72-R104 HydrophobicContact CD2-CG 4.38Å; F72-R104 HydrophobicContact CE1-CB 4.46Å; F72-R104 VanDerWaalsContact CE1-CD 3.4Å; F72-R104 HydrophobicContact CE1-CG 4.38Å; F72-R104 HydrophobicContact CE2-CB 4.22Å; F72-R104 HydrophobicContact CE2-CG 4.28Å; F72-R104 HydrophobicContact CG-CB 3.7Å; F72-R104 HydrophobicContact CG-CG 4.44Å; F72-R104 HydrophobicContact CZ-CG 4.3Å; H73-R104 PolarHBondContact CE1-NH1 2.67Å; H73-R104 PolarHBondContact NE2-NH1 3.13Å; R104-N106 PolarHBondContact O-ND2 2.92Å; R104-Y111 HydrophobicContact CG-CD2 3.87Å; R104-Y111 HydrophobicContact CG-CE2 3.52Å; R104-Y111 PolarHBondContact NE-O 3Å; R104-Y111 PolarHBondContact NH2-O 3.05Å
105R93.7Very high91.2Very high199 Ų19952.9 Ų52.975%0.75127%0.27SS*.SBendtrans-90.8108172.9-71.8-179.2177.7-161.30.9108.9P103 Y111P103-R105 VanDerWaalsContact C-N 3.27Å; P103-R105 WeakPolarHBondContact CG-O 2.9Å; P103-R105 PolarHBondContact O-N 2.99Å; R105-Y111 HydrophobicContact CG-CD2 3.59Å; R105-Y111 HydrophobicContact CG-CE2 3.75Å
106N92.2Very high89.8Confident28 Ų2859.1 Ų59.115%0.1530%0.303CS..  trans-141.4171.4179.564.578.2000110.8L102 P103 R104 F108 Y109L102-N106 HydrophobicContact CB-CB 4.28Å; P103-N106 PolarHBondContact O-ND2 3.41Å; R104-N106 PolarHBondContact O-ND2 2.92Å; N106-F108 VanDerWaalsContact C-N 3.32Å; N106-F108 PolarHBondContact O-N 3.27Å; N106-F108 PolarHBondContact OD1-N 3Å; N106-Y109 PolarHBondContact OD1-N 3.06Å
107D89.4Confident88.3Confident147 Ų14765 Ų6579%0.78633%0.332SS*.SBendtrans-83.8-6-174.1-58.6-35.2000113.8
108F88.9Confident86.2Confident29 Ų2969.6 Ų69.613%0.12736%0.356CS..SBendtrans-105.8-33.2-168-52.9-57.9000113.3Q37 L38 L102 N106 N331Q37-F108 HydrophobicContact CB-CD1 3.58Å; Q37-F108 HydrophobicContact CB-CE1 3.69Å; Q37-F108 HydrophobicContact CB-CG 4.33Å; Q37-F108 HydrophobicContact CG-CB 3.95Å; Q37-F108 HydrophobicContact CG-CD1 3.44Å; Q37-F108 VanDerWaalsContact CG-CD1 3.44Å; Q37-F108 HydrophobicContact CG-CE1 4.07Å; Q37-F108 HydrophobicContact CG-CG 3.77Å; L38-F108 HydrophobicContact CB-CZ 4.24Å; L38-F108 HydrophobicContact CD1-CE1 4.03Å; L38-F108 HydrophobicContact CD1-CZ 3.84Å; L38-F108 HydrophobicContact CG-CE1 3.86Å; L38-F108 HydrophobicContact CG-CZ 3.85Å; L102-F108 HydrophobicContact CD1-CD2 3.62Å; L102-F108 HydrophobicContact CD1-CE2 4.28Å; L102-F108 HydrophobicContact CD2-CD2 3.81Å; L102-F108 HydrophobicContact CD2-CE2 3.66Å; L102-F108 HydrophobicContact CG-CD2 4.38Å; N106-F108 VanDerWaalsContact C-N 3.32Å; N106-F108 PolarHBondContact O-N 3.27Å; N106-F108 PolarHBondContact OD1-N 3Å; F108-N331 HydrophobicContact CZ-CB 4.49Å
109Y89.9Confident84.3Confident18 Ų1873.6 Ų73.67%0.07138%0.383CS..SBendtrans-128.9146.7-172.5-56.4-74.8000111.9S21 H22 F24 W34 L35 L102 N106S21-Y109 WeakPolarHBondContact CB-OH 3.25Å; S21-Y109 WeakPolarHBondContact O-CE1 3.27Å; S21-Y109 PolarHBondContact O-OH 2.99Å; H22-Y109 HydrophobicContact CB-CD1 4.27Å; H22-Y109 HydrophobicContact CB-CE1 4.18Å; F24-Y109 HydrophobicContact CE1-CD1 4.09Å; F24-Y109 AromaticContact CE1-CD2 3.67Å; F24-Y109 HydrophobicContact CE1-CD2 3.67Å; F24-Y109 HydrophobicContact CE1-CE1 4.08Å; F24-Y109 AromaticContact CE1-CE2 3.66Å; F24-Y109 HydrophobicContact CE1-CE2 3.66Å; F24-Y109 AromaticContact CE1-CG 3.86Å; F24-Y109 HydrophobicContact CE1-CG 3.86Å; F24-Y109 AromaticContact CE1-CZ 3.83Å; F24-Y109 AromaticContact CZ-CD1 3.76Å; F24-Y109 HydrophobicContact CZ-CD1 3.76Å; F24-Y109 AromaticContact CZ-CD2 3.82Å; F24-Y109 HydrophobicContact CZ-CD2 3.82Å; F24-Y109 HydrophobicContact CZ-CE1 4.17Å; F24-Y109 HydrophobicContact CZ-CE2 4.22Å; F24-Y109 AromaticContact CZ-CG 3.54Å; F24-Y109 HydrophobicContact CZ-CG 3.54Å; W34-Y109 PolarHBondContact O-OH 2.86Å; L35-Y109 WeakPolarHBondContact CA-OH 3.15Å; L35-Y109 HydrophobicContact CD1-CE2 3.85Å; L35-Y109 WeakPolarHBondContact O-CE2 3.48Å; L35-Y109 PolarHBondContact O-OH 2.83Å; L102-Y109 HydrophobicContact CD1-CD2 3.97Å; L102-Y109 HydrophobicContact CD1-CE2 3.73Å; N106-Y109 PolarHBondContact OD1-N 3.06Å
110P87.8Confident82.2Confident97 Ų9780 Ų8063%0.6342%0.417SS*.  trans-60.6153.7173.5-21.333.2000112.7N112P110-N112 PolarHBondContact O-N 2.83Å
111Y88.1Confident80.2Confident124 Ų12485.9 Ų85.949%0.48644%0.439SS..SBendtrans-67.7-24.2175.9-173.9-90.5000113.3R104 R105R104-Y111 HydrophobicContact CG-CD2 3.87Å; R104-Y111 HydrophobicContact CG-CE2 3.52Å; R104-Y111 PolarHBondContact NE-O 3Å; R104-Y111 PolarHBondContact NH2-O 3.05Å; R105-Y111 HydrophobicContact CG-CD2 3.59Å; R105-Y111 HydrophobicContact CG-CE2 3.75Å
112N86.3Confident77.9Confident113 Ų11390.4 Ų90.460%0.60447%0.468SS*.SBendtrans-104.4146.2177.3-66.4-32.6000109.3P110P110-N112 PolarHBondContact O-N 2.83Å
113P80.4Confident75.6Confident96 Ų9699.5 Ų99.562%0.62351%0.51SS*.PPolyproline II helixtrans-60.7152.9176.628.4-34.4000111.2
114P75.5Confident73.5Confident52 Ų52105.8 Ų105.834%0.33853%0.532SS..PPolyproline II helixtrans-60.8159.5168.128-32.7000110.8
115S73.1Confident71.3Confident71 Ų71108.4 Ų108.450%0.49755%0.549SS..PPolyproline II helixtrans-73.8140.4172.6-177.50000109.8E117S115-E117 PolarHBondContact O-N 2.87Å; S115-E117 PolarHBondContact OG-N 2.82Å
116D69.3Low69.3Low136 Ų136103.8 Ų103.873%0.72755%0.545SS*.THydrogen-bonded Turntrans-72.5-10.7175.8-59.8-31.1000112.7
117E66.3Low67.1Low179 Ų179104.7 Ų104.784%0.83655%0.554SS**THydrogen-bonded Turntrans-109.7-5.5-170.8-60.1-169.514900115.1S115 P119S115-E117 PolarHBondContact O-N 2.87Å; S115-E117 PolarHBondContact OG-N 2.82Å; E117-P119 VanDerWaalsContact O-CD 3.28Å; E117-P119 WeakPolarHBondContact O-CD 3.3Å
118D54.8Low65.3Low98 Ų98101.4 Ų101.452%0.52454%0.539SS..  trans-116.591.6-172.7-163.7-4000112.8N120D118-N120 PolarHBondContact O-N 2.69Å; D118-N120 WeakPolarHBondContact OD1-CA 3.4Å; D118-N120 WeakPolarHBondContact OD1-CB 3.39Å; D118-N120 PolarHBondContact OD1-N 2.84Å
119P58.3Low64Low89 Ų89101.1 Ų101.158%0.57854%0.538SS*.THydrogen-bonded Turntrans-71.2-5.3173.830.2-34.6000112.7E117 W121E117-P119 VanDerWaalsContact O-CD 3.28Å; E117-P119 WeakPolarHBondContact O-CD 3.3Å; P119-W121 PolarHBondContact O-N 2.93Å
120N53.8Low62.5Low133 Ų133104 Ų10471%0.71156%0.561SS**THydrogen-bonded Turntrans-87.918.7-170.8-13610.9000112.9D118 T122D118-N120 PolarHBondContact O-N 2.69Å; D118-N120 WeakPolarHBondContact OD1-CA 3.4Å; D118-N120 WeakPolarHBondContact OD1-CB 3.39Å; D118-N120 PolarHBondContact OD1-N 2.84Å; N120-T122 VanDerWaalsContact C-N 3.31Å; N120-T122 PolarHBondContact O-N 2.87Å
121W55.4Low61.4Low125 Ų125101.5 Ų101.547%0.47355%0.545SS..SBendtrans-57.6101.4164.4-169.289.8000107.4P119 E123 R124P119-W121 PolarHBondContact O-N 2.93Å; W121-E123 PolarHBondContact O-N 3.04Å; W121-R124 VanDerWaalsContact CH2-NH2 3.31Å; W121-R124 HydrophobicContact CZ3-CB 4.37Å
122T49.2Very low60.8Low108 Ų10898.1 Ų98.166%0.66355%0.548SS*.  trans-43111.4-170.946.20000109.8N120 R124N120-T122 VanDerWaalsContact C-N 3.31Å; N120-T122 PolarHBondContact O-N 2.87Å; T122-R124 VanDerWaalsContact C-N 3.31Å; T122-R124 PolarHBondContact O-N 3.4Å
123E47.2Very low60.7Low191 Ų19194.8 Ų94.889%0.89353%0.532SS*.  trans-49.595178.7-68.1-178.7158.700108.9W121W121-E123 PolarHBondContact O-N 3.04Å
124R51.6Low61.1Low146 Ų14695.6 Ų95.655%0.55153%0.526SS*.  trans-68.5136.8163.8-73.9-164.8-78.8-117.312.1106.1W121 T122 P126W121-R124 VanDerWaalsContact CH2-NH2 3.31Å; W121-R124 HydrophobicContact CZ3-CB 4.37Å; T122-R124 VanDerWaalsContact C-N 3.31Å; T122-R124 PolarHBondContact O-N 3.4Å; R124-P126 WeakPolarHBondContact O-CD 3.32Å
125D46.6Very low61.9Low97 Ų9794.1 Ų94.152%0.51952%0.515SS..  trans-42.1114.1-177.4-176.8-19000110.6C127 V128D125-C127 PolarHBondContact O-N 3.02Å; D125-C127 VanDerWaalsContact OD1-CB 3.32Å; D125-C127 WeakPolarHBondContact OD1-CB 3.26Å; D125-C127 PolarHBondContact OD1-N 3.15Å; D125-V128 PolarHBondContact O-N 3.07Å
126P50.7Low62.8Low102 Ų10290.8 Ų90.866%0.66249%0.491SS*.THydrogen-bonded Turntrans-61.8-8.5-175.220.8-30.7000113.3R124R124-P126 WeakPolarHBondContact O-CD 3.32Å
127C46.5Very low63.9Low48 Ų4886 Ų8632%0.32446%0.464SS..THydrogen-bonded Turntrans-91.4-9.9176.3-58.80000114.5D125 L135D125-C127 PolarHBondContact O-N 3.02Å; D125-C127 VanDerWaalsContact OD1-CB 3.32Å; D125-C127 WeakPolarHBondContact OD1-CB 3.26Å; D125-C127 PolarHBondContact OD1-N 3.15Å; C127-L135 PolarHBondContact O-N 3.16Å; C127-L135 VanDerWaalsContact O-N 3.17Å
128V50.8Low65.1Low78 Ų7877.8 Ų77.847%0.47343%0.426SS..BIsolated β-bridgetrans-122.8107-178.1-174.80000110D125D125-V128 PolarHBondContact O-N 3.07Å
129H61.9Low67Low23 Ų2373.3 Ų73.311%0.10640%0.402CS..  trans-64.7148.8172.5-138.1-44.1000109.8Q37 S131 G132 V133Q37-H129 WeakPolarHBondContact CB-CE1 3.46Å; Q37-H129 VanDerWaalsContact CB-ND1 3.32Å; Q37-H129 WeakPolarHBondContact CB-ND1 3.13Å; Q37-H129 WeakPolarHBondContact CG-CE1 3.5Å; Q37-H129 WeakPolarHBondContact CG-ND1 3.47Å; Q37-H129 PolarHBondContact NE2-CE1 3.09Å; Q37-H129 PolarHBondContact OE1-CE1 3.36Å; Q37-H129 PolarHBondContact OE1-ND1 2.9Å; H129-S131 PolarHBondContact O-N 3.35Å; H129-G132 PolarHBondContact O-N 3.39Å; H129-V133 HydrophobicContact CB-CB 4.33Å; H129-V133 PolarHBondContact N-O 2.88Å
130S59.8Low68.7Low79 Ų7969.2 Ų69.255%0.55238%0.376SS*.THydrogen-bonded Turntrans-59.8-18.3-179.982.80000113.9Q37 G132Q37-S130 PolarHBondContact OE1-OG 3.08Å; S130-G132 VanDerWaalsContact C-N 3.28Å; S130-G132 PolarHBondContact O-N 2.82Å
131S64.5Low70.6Confident43 Ų4363.1 Ų63.130%0.30134%0.344SS..THydrogen-bonded Turntrans-76-4.7171.958.10000115.2Q37 H129 V133Q37-S131 WeakPolarHBondContact O-CB 3.22Å; Q37-S131 PolarHBondContact O-OG 2.86Å; H129-S131 PolarHBondContact O-N 3.35Å; S131-V133 VanDerWaalsContact C-N 3.3Å; S131-V133 WeakPolarHBondContact OG-CG2 3.29Å
132G75.3Confident72.4Confident54 Ų5458 Ų5856%0.55733%0.327SS*.  trans822.7-176.200000114.6H129 S130 K134H129-G132 PolarHBondContact O-N 3.39Å; S130-G132 VanDerWaalsContact C-N 3.28Å; S130-G132 PolarHBondContact O-N 2.82Å; G132-K134 PolarHBondContact O-N 2.85Å
133V82.9Confident74.4Confident43 Ų4353.4 Ų53.426%0.26130%0.301SS..PPolyproline II helixtrans-68.9121.4174179.80000109.3H129 S131 L135 P142H129-V133 HydrophobicContact CB-CB 4.33Å; H129-V133 PolarHBondContact N-O 2.88Å; S131-V133 VanDerWaalsContact C-N 3.3Å; S131-V133 WeakPolarHBondContact OG-CG2 3.29Å; V133-L135 HydrophobicContact CG1-CD2 4.06Å; V133-P142 HydrophobicContact CG1-CB 4.25Å; V133-P142 HydrophobicContact CG1-CG 4.49Å
134K89.3Confident76.3Confident113 Ų11352 Ų5249%0.49129%0.294SS..BIsolated β-bridgetrans-77.8125173.3-63.4-172.5-179.1-1750109.4G132 G143 S154G132-K134 PolarHBondContact O-N 2.85Å; K134-G143 WeakPolarHBondContact O-CA 3.36Å; K134-G143 PolarHBondContact O-N 3.28Å; K134-S154 WeakPolarHBondContact CD-OG 3.26Å
135L91.9Very high78.1Confident21 Ų2149.6 Ų49.611%0.1129%0.288CS..BIsolated β-bridgetrans-93.2153.2179.5-58-178.3000111.5I40 C127 V133 K137I40-L135 HydrophobicContact CD1-CD2 4.47Å; C127-L135 PolarHBondContact O-N 3.16Å; C127-L135 VanDerWaalsContact O-N 3.17Å; V133-L135 HydrophobicContact CG1-CD2 4.06Å; L135-K137 PolarHBondContact O-N 3.38Å
136C93.8Very high80.3Confident1 Ų147.8 Ų47.81%0.00728%0.28CS..BIsolated β-bridgetrans-66.1123.8172.7179.10000109.1L138 C139 G140 C141 S154 C156C136-L138 PolarHBondContact O-N 3.4Å; C136-C139 VanDerWaalsContact CB-SG 3.56Å; C136-C139 PolarHBondContact O-N 2.92Å; C136-C139 VanDerWaalsContact SG-SG 3.62Å; C136-G140 WeakPolarHBondContact O-CA 3.4Å; C136-G140 PolarHBondContact O-N 3.11Å; C136-C141 WeakPolarHBondContact CB-O 3.47Å; C136-C141 PolarHBondContact N-O 2.96Å; C136-S154 CarbonylContact C-O 3.58Å; C136-S154 VanDerWaalsContact CA-O 3.28Å; C136-S154 WeakPolarHBondContact CA-O 3.45Å; C136-C156 HydrophobicContact CB-CB 4.1Å
137K91.6Very high82.2Confident34 Ų3443 Ų4315%0.14825%0.249CC..THydrogen-bonded Turntrans-53.7-39.6178.1179.7174.6173.5-174.30112.3K31 L135 V153 S154 Y155 E172K31-K137 VanDerWaalsContact CE-O 3.24Å; K31-K137 WeakPolarHBondContact CE-O 3.19Å; K31-K137 PolarHBondContact NZ-O 2.93Å; L135-K137 PolarHBondContact O-N 3.38Å; K137-V153 HydrophobicContact CD-CB 4.29Å; K137-V153 HydrophobicContact CD-CG1 3.86Å; K137-S154 PolarHBondContact N-O 3.32Å; K137-Y155 HydrophobicContact CB-CE1 4.26Å; K137-E172 IonicContact NZ-OE2 3.26Å; K137-E172 PolarHBondContact NZ-OE2 3.11Å
138L92Very high84.3Confident8 Ų845.1 Ų45.14%0.04226%0.264CS..THydrogen-bonded Turntrans-77.5-47.4-174.9-170.467.3000113.5C136 H160 I163 D164 S184 F186 L187C136-L138 PolarHBondContact O-N 3.4Å; L138-H160 HydrophobicContact CB-CB 4.28Å; L138-H160 HydrophobicContact CD2-CB 3.76Å; L138-I163 HydrophobicContact CD1-CG2 4.4Å; L138-I163 HydrophobicContact CD2-CB 3.89Å; L138-I163 HydrophobicContact CD2-CD1 4.33Å; L138-I163 HydrophobicContact CD2-CG2 3.81Å; L138-D164 HydrophobicContact CD1-CB 4.44Å; L138-S184 VanDerWaalsContact CD1-OG 3.28Å; L138-S184 WeakPolarHBondContact CD1-OG 3.49Å; L138-F186 HydrophobicContact CD1-CB 4.24Å; L138-F186 HydrophobicContact CD2-CB 3.86Å; L138-F186 HydrophobicContact CD2-CD1 4.49Å; L138-F186 HydrophobicContact CD2-CG 4.14Å; L138-F186 HydrophobicContact CG-CB 3.97Å; L138-F186 HydrophobicContact CG-CD1 4.43Å; L138-F186 HydrophobicContact CG-CG 4.41Å; L138-L187 WeakPolarHBondContact O-CD2 3.49Å; L138-L187 WeakPolarHBondContact O-CG 3.31Å
139C93.9Very high86.2Confident3 Ų348 Ų482%0.0227%0.27CS..THydrogen-bonded Turntrans-116.1-10.7-169.670.80000115.8P32 C136 C141 C156 H160 F186P32-C139 VanDerWaalsContact CD-O 3.31Å; P32-C139 WeakPolarHBondContact CD-O 3.45Å; C136-C139 VanDerWaalsContact CB-SG 3.56Å; C136-C139 PolarHBondContact O-N 2.92Å; C136-C139 VanDerWaalsContact SG-SG 3.62Å; C139-C141 VanDerWaalsContact C-N 3.25Å; C139-C141 PolarHBondContact O-N 2.89Å; C139-C141 PolarHBondContact SG-N 2.94Å; C139-C156 VanDerWaalsContact SG-SG 3.69Å; C139-H160 PolarHBondContact SG-CE1 2.95Å; C139-H160 PolarHBondContact SG-ND1 2.83Å; C139-F186 HydrophobicContact CB-CD1 3.96Å; C139-F186 HydrophobicContact CB-CE1 3.67Å
140G93Very high87.5Confident3 Ų348.4 Ų48.43%0.03128%0.275CS..SBendtrans76.21.2-176.900000115.6W34 C136W34-G140 PolarHBondContact NE1-O 3.43Å; C136-G140 WeakPolarHBondContact O-CA 3.4Å; C136-G140 PolarHBondContact O-N 3.11Å
141C94.4Very high88.9Confident6 Ų650.3 Ų50.34%0.04128%0.275CS..SBendtrans-80.5162.2172.3-51.50000111.4L46 C136 C139 G143L46-C141 HydrophobicContact CD1-CB 3.98Å; C136-C141 WeakPolarHBondContact CB-O 3.47Å; C136-C141 PolarHBondContact N-O 2.96Å; C139-C141 VanDerWaalsContact C-N 3.25Å; C139-C141 PolarHBondContact O-N 2.89Å; C139-C141 PolarHBondContact SG-N 2.94Å; C141-G143 PolarHBondContact O-N 3.47Å
142P93.6Very high90Very high17 Ų1752.2 Ų52.211%0.1129%0.294CS..BIsolated β-bridgetrans-53123.4-179.4-2937.5000113.5I40 P41 V133 C156I40-P142 HydrophobicContact CB-CG 3.65Å; I40-P142 HydrophobicContact CG2-CG 3.51Å; P41-P142 VanDerWaalsContact O-CD 3.31Å; P41-P142 WeakPolarHBondContact O-CD 3.34Å; V133-P142 HydrophobicContact CG1-CB 4.25Å; V133-P142 HydrophobicContact CG1-CG 4.49Å; P142-C156 VanDerWaalsContact O-CB 3.23Å; P142-C156 WeakPolarHBondContact O-CB 3.28Å
143G90.2Very high90.6Very high11 Ų1150.9 Ų50.911%0.11328%0.275CS..  trans-100.7112.6-177.700000111.8K134 C141 Y155K134-G143 WeakPolarHBondContact O-CA 3.36Å; K134-G143 PolarHBondContact O-N 3.28Å; C141-G143 PolarHBondContact O-N 3.47Å; G143-Y155 CarbonylContact C-O 3.54Å; G143-Y155 WeakPolarHBondContact CA-O 3.36Å
144Q87.3Confident91.1Very high161 Ų16149.2 Ų49.275%0.75227%0.265SS*.  trans-96.8-16.9178.6-63.4179.4-3.800113Y155Q144-Y155 PolarHBondContact N-O 2.96Å; Q144-Y155 VanDerWaalsContact N-O 3.15Å
145K89.8Confident91.4Very high97 Ų9743.9 Ų43.942%0.42224%0.242SC..EExtended strand (participates in β ladder)trans-107.5125.4-176.1-61.1177.8-175.8174.70109.7S154 Y155K145-S154 CarbonylContact O-C 3.43Å; K145-S154 VanDerWaalsContact O-CA 3.27Å; K145-S154 WeakPolarHBondContact O-CA 3.14Å; K145-Y155 PolarHBondContact N-O 2.71Å; K145-Y155 PolarHBondContact O-N 3.2Å
146V92.4Very high91.5Very high58 Ų5843.2 Ų43.235%0.35224%0.239SC..EExtended strand (participates in β ladder)trans-95.6150174.1-64.50000111S148 V153V146-S148 PolarHBondContact O-N 3.24Å; V146-V153 WeakPolarHBondContact CA-O 3.48Å
147C92Very high91.6Very high2 Ų243.2 Ų43.21%0.01424%0.239CC..  trans-59.3122.3171.3178.80000110K149 H151 V153 Y155 H169C147-K149 PolarHBondContact O-N 2.75Å; C147-K149 VanDerWaalsContact O-N 3.14Å; C147-H151 WeakPolarHBondContact O-CA 3.38Å; C147-H151 PolarHBondContact O-N 2.63Å; C147-V153 HydrophobicContact CB-CG2 3.65Å; C147-V153 PolarHBondContact N-O 3.41Å; C147-Y155 HydrophobicContact CB-CE2 4.32Å; C147-H169 PolarHBondContact SG-NE2 2.95Å
148S90.8Very high91.7Very high93 Ų9347.9 Ų47.965%0.6526%0.259SS*.THydrogen-bonded Turntrans-69-8.6-178.153.90000114.6V146 H151V146-S148 PolarHBondContact O-N 3.24Å; S148-H151 PolarHBondContact O-NE2 3.46Å
149K90.1Very high91.8Very high138 Ų13851.3 Ų51.360%0.628%0.275SS*.THydrogen-bonded Turntrans-96.3-50178.2-70.6-175.9178-177.90112.7C147 W165C147-K149 PolarHBondContact O-N 2.75Å; C147-K149 VanDerWaalsContact O-N 3.14Å; K149-W165 HydrophobicContact CD-CH2 3.81Å; K149-W165 HydrophobicContact CD-CZ3 4.42Å
150C89.3Confident91.8Very high31 Ų3151.3 Ų51.321%0.20928%0.275CS..THydrogen-bonded Turntrans-103.4-19.4-176.5690000114.1A152C150-A152 HydrophobicContact CB-CB 4.35Å; C150-A152 PolarHBondContact O-N 3.41Å; C150-A152 PolarHBondContact SG-N 2.85Å
151H89.5Confident91.8Very high119 Ų11953.3 Ų53.355%0.55128%0.283SS*.SBendtrans54.28-173-59.9-87.2000115.9C147 S148C147-H151 WeakPolarHBondContact O-CA 3.38Å; C147-H151 PolarHBondContact O-N 2.63Å; S148-H151 PolarHBondContact O-NE2 3.46Å
152A86.2Confident91.8Very high83 Ų8355.8 Ų55.869%0.68630%0.298SS*.  trans-90.9-29.2-173.900000113.7C150C150-A152 HydrophobicContact CB-CB 4.35Å; C150-A152 PolarHBondContact O-N 3.41Å; C150-A152 PolarHBondContact SG-N 2.85Å
153V89.3Confident91.7Very high26 Ų2657.4 Ų57.416%0.15831%0.305CS..  trans-112.4145.6-177.6-61.80000111K137 V146 C147 Y155 H169K137-V153 HydrophobicContact CD-CB 4.29Å; K137-V153 HydrophobicContact CD-CG1 3.86Å; V146-V153 WeakPolarHBondContact CA-O 3.48Å; C147-V153 HydrophobicContact CB-CG2 3.65Å; C147-V153 PolarHBondContact N-O 3.41Å; V153-Y155 HydrophobicContact CG2-CE2 3.69Å; V153-Y155 WeakPolarHBondContact CG2-OH 3.37Å; V153-H169 WeakPolarHBondContact CG2-NE2 3.18Å
154S92.8Very high91.7Very high9 Ų957.1 Ų57.16%0.06330%0.302CS..EExtended strand (participates in β ladder)trans-115.2152.8-179.9-54.60000111.5K134 C136 K137 K145K134-S154 WeakPolarHBondContact CD-OG 3.26Å; C136-S154 CarbonylContact C-O 3.58Å; C136-S154 VanDerWaalsContact CA-O 3.28Å; C136-S154 WeakPolarHBondContact CA-O 3.45Å; K137-S154 PolarHBondContact N-O 3.32Å; K145-S154 CarbonylContact O-C 3.43Å; K145-S154 VanDerWaalsContact O-CA 3.27Å; K145-S154 WeakPolarHBondContact O-CA 3.14Å
155Y95Very high91.9Very high0 Ų052.7 Ų52.70%028%0.278CS..EExtended strand (participates in β ladder)trans-137.6144.7-179.7-57-80.2000110.7K137 G143 Q144 K145 C147 V153 H160 Q161 D164 H169K137-Y155 HydrophobicContact CB-CE1 4.26Å; G143-Y155 CarbonylContact C-O 3.54Å; G143-Y155 WeakPolarHBondContact CA-O 3.36Å; Q144-Y155 PolarHBondContact N-O 2.96Å; Q144-Y155 VanDerWaalsContact N-O 3.15Å; K145-Y155 PolarHBondContact N-O 2.71Å; K145-Y155 PolarHBondContact O-N 3.2Å; C147-Y155 HydrophobicContact CB-CE2 4.32Å; V153-Y155 HydrophobicContact CG2-CE2 3.69Å; V153-Y155 WeakPolarHBondContact CG2-OH 3.37Å; Y155-H160 HydrophobicContact CD1-CB 4.46Å; Y155-Q161 HydrophobicContact CD1-CB 4.13Å; Y155-Q161 HydrophobicContact CD2-CB 3.71Å; Y155-Q161 HydrophobicContact CD2-CG 3.74Å; Y155-Q161 HydrophobicContact CE1-CB 4.46Å; Y155-Q161 HydrophobicContact CE2-CB 4.05Å; Y155-Q161 HydrophobicContact CE2-CG 3.68Å; Y155-Q161 HydrophobicContact CG-CB 3.74Å; Y155-Q161 HydrophobicContact CG-CG 4.28Å; Y155-D164 HydrophobicContact CE1-CB 3.64Å; Y155-D164 VanDerWaalsContact CE1-OD2 3.24Å; Y155-D164 WeakPolarHBondContact CE1-OD2 3.36Å; Y155-D164 VanDerWaalsContact CZ-OD2 3.29Å; Y155-D164 PolarHBondContact OH-OD2 2.98Å; Y155-H169 PolarHBondContact OH-CD2 2.85Å
156C94.9Very high91.9Very high8 Ų855.9 Ų55.95%0.05429%0.292CS..SBendtrans-75.4-31.7174.965.80000111.7L43 C136 C139 P142 H160L43-C156 WeakPolarHBondContact CD2-O 3.42Å; C136-C156 HydrophobicContact CB-CB 4.1Å; C139-C156 VanDerWaalsContact SG-SG 3.69Å; P142-C156 VanDerWaalsContact O-CB 3.23Å; P142-C156 WeakPolarHBondContact O-CB 3.28Å; C156-H160 PolarHBondContact SG-ND1 3.33Å
157S94.9Very high91.6Very high0 Ų057.8 Ų57.80%030%0.297CS..SBendtrans-140.9167-175.572.70000112.5P54 E159 H160 Q161P54-S157 VanDerWaalsContact CG-OG 3.3Å; P54-S157 WeakPolarHBondContact CG-OG 3.47Å; S157-E159 VanDerWaalsContact C-N 3.27Å; S157-E159 WeakPolarHBondContact CB-OE2 3.25Å; S157-H160 PolarHBondContact OG-N 2.8Å; S157-Q161 PolarHBondContact O-N 2.97Å
158K93.9Very high91.3Very high133 Ų13358.8 Ų58.858%0.57830%0.303SS*.Hα-helixtrans-72.2-30.3174.8-177.2-176.3176.6-173.80110.5Q161 T162K158-Q161 PolarHBondContact O-N 2.94Å; K158-T162 WeakPolarHBondContact O-CB 3.46Å; K158-T162 PolarHBondContact O-N 2.69Å; K158-T162 PolarHBondContact O-OG1 3.15Å
159E94Very high91.1Very high80 Ų8054.6 Ų54.637%0.37427%0.273SS..Hα-helixtrans-61.2-51.4177.8-66.756.1-128.900109.2L53 S157 Q161 T162 I163L53-E159 HydrophobicContact CD2-CG 3.79Å; S157-E159 VanDerWaalsContact C-N 3.27Å; S157-E159 WeakPolarHBondContact CB-OE2 3.25Å; E159-Q161 PolarHBondContact O-N 3.19Å; E159-T162 WeakPolarHBondContact O-CB 3.43Å; E159-T162 PolarHBondContact O-N 3.08Å; E159-T162 VanDerWaalsContact O-N 3.14Å; E159-I163 WeakPolarHBondContact O-CG1 3.31Å; E159-I163 PolarHBondContact O-N 3.3Å
160H93.9Very high91.1Very high2 Ų254.9 Ų54.91%0.00928%0.275CS..Hα-helixtrans-64.8-38.4177.5-74.8-166.9000112.7P54 L138 C139 Y155 C156 S157 T162 I163 D164 F186P54-H160 WeakPolarHBondContact CB-NE2 3.36Å; L138-H160 HydrophobicContact CB-CB 4.28Å; L138-H160 HydrophobicContact CD2-CB 3.76Å; C139-H160 PolarHBondContact SG-CE1 2.95Å; C139-H160 PolarHBondContact SG-ND1 2.83Å; Y155-H160 HydrophobicContact CD1-CB 4.46Å; C156-H160 PolarHBondContact SG-ND1 3.33Å; S157-H160 PolarHBondContact OG-N 2.8Å; H160-T162 VanDerWaalsContact C-N 3.32Å; H160-T162 PolarHBondContact O-N 2.76Å; H160-I163 PolarHBondContact O-N 2.82Å; H160-D164 VanDerWaalsContact O-CB 3.3Å; H160-D164 WeakPolarHBondContact O-CB 3.41Å; H160-D164 PolarHBondContact O-N 3.25Å; H160-F186 AromaticContact CE1-CE1 3.51Å; H160-F186 AromaticContact CE1-CZ 3.55Å; H160-F186 AromaticContact NE2-CD2 3.93Å; H160-F186 AromaticContact NE2-CE1 3.57Å; H160-F186 AromaticContact NE2-CE2 3.39Å; H160-F186 WeakPolarHBondContact NE2-CE2 3.39Å; H160-F186 AromaticContact NE2-CZ 3.19Å; H160-F186 WeakPolarHBondContact NE2-CZ 3.38Å
161Q93.3Very high90.9Very high45 Ų4561 Ų6121%0.2130%0.298CS..Hα-helixtrans-60.9-43.7172.8-177179.419.900111.3Y155 S157 K158 E159 W165Y155-Q161 HydrophobicContact CD1-CB 4.13Å; Y155-Q161 HydrophobicContact CD2-CB 3.71Å; Y155-Q161 HydrophobicContact CD2-CG 3.74Å; Y155-Q161 HydrophobicContact CE1-CB 4.46Å; Y155-Q161 HydrophobicContact CE2-CB 4.05Å; Y155-Q161 HydrophobicContact CE2-CG 3.68Å; Y155-Q161 HydrophobicContact CG-CB 3.74Å; Y155-Q161 HydrophobicContact CG-CG 4.28Å; S157-Q161 PolarHBondContact O-N 2.97Å; K158-Q161 PolarHBondContact O-N 2.94Å; E159-Q161 PolarHBondContact O-N 3.19Å; Q161-W165 WeakPolarHBondContact O-CB 3.2Å; Q161-W165 PolarHBondContact O-N 3.3Å
162T93.8Very high90.8Very high59 Ų5956.5 Ų56.536%0.36228%0.277SS..Hα-helixtrans-63.6-43.8179.1-58.50000111.9K158 E159 H160 K166K158-T162 WeakPolarHBondContact O-CB 3.46Å; K158-T162 PolarHBondContact O-N 2.69Å; K158-T162 PolarHBondContact O-OG1 3.15Å; E159-T162 WeakPolarHBondContact O-CB 3.43Å; E159-T162 PolarHBondContact O-N 3.08Å; E159-T162 VanDerWaalsContact O-N 3.14Å; H160-T162 VanDerWaalsContact C-N 3.32Å; H160-T162 PolarHBondContact O-N 2.76Å; T162-K166 HydrophobicContact CG2-CD 4.4Å; T162-K166 WeakPolarHBondContact O-CG 3.49Å; T162-K166 PolarHBondContact O-N 3.02Å; T162-K166 VanDerWaalsContact O-N 3.1Å
163I91.4Very high90.8Very high50 Ų5053.4 Ų53.426%0.25625%0.25SS..Hα-helixtrans-61.3-56.9176.8-65.9164.2000109.3L138 E159 H160 W165 K166 H167 P185 F186L138-I163 HydrophobicContact CD1-CG2 4.4Å; L138-I163 HydrophobicContact CD2-CB 3.89Å; L138-I163 HydrophobicContact CD2-CD1 4.33Å; L138-I163 HydrophobicContact CD2-CG2 3.81Å; E159-I163 WeakPolarHBondContact O-CG1 3.31Å; E159-I163 PolarHBondContact O-N 3.3Å; H160-I163 PolarHBondContact O-N 2.82Å; I163-W165 VanDerWaalsContact C-N 3.27Å; I163-W165 PolarHBondContact O-N 2.95Å; I163-K166 PolarHBondContact O-N 2.77Å; I163-H167 PolarHBondContact O-CD2 2.81Å; I163-H167 VanDerWaalsContact O-CD2 3.23Å; I163-H167 PolarHBondContact O-N 2.97Å; I163-H167 VanDerWaalsContact O-N 3.16Å; I163-P185 HydrophobicContact CG2-CG 3.61Å; I163-F186 HydrophobicContact CD1-CD2 4.46Å
164D91.4Very high90.6Very high6 Ų656.7 Ų56.73%0.03227%0.273CS..Hα-helixtrans-57.9-39.6-179.2-170.157.9000112.2L138 Y155 H160 K166 H167 C168 H169L138-D164 HydrophobicContact CD1-CB 4.44Å; Y155-D164 HydrophobicContact CE1-CB 3.64Å; Y155-D164 VanDerWaalsContact CE1-OD2 3.24Å; Y155-D164 WeakPolarHBondContact CE1-OD2 3.36Å; Y155-D164 VanDerWaalsContact CZ-OD2 3.29Å; Y155-D164 PolarHBondContact OH-OD2 2.98Å; H160-D164 VanDerWaalsContact O-CB 3.3Å; H160-D164 WeakPolarHBondContact O-CB 3.41Å; H160-D164 PolarHBondContact O-N 3.25Å; D164-K166 PolarHBondContact O-N 3.37Å; D164-H167 PolarHBondContact O-N 3.24Å; D164-C168 PolarHBondContact O-N 3.03Å; D164-C168 PolarHBondContact OD1-SG 2.93Å; D164-H169 PolarHBondContact O-N 2.89Å; D164-H169 WeakPolarHBondContact OD2-CB 3.44Å; D164-H169 IonicContact OD2-CG 3.97Å
165W90.9Very high89.9Confident67 Ų6762.5 Ų62.525%0.25430%0.297SS..Iπ-helixtrans-60.4-43.5175.7-173.2-97.1000112.9K149 Q161 I163 H169 K170 C173K149-W165 HydrophobicContact CD-CH2 3.81Å; K149-W165 HydrophobicContact CD-CZ3 4.42Å; Q161-W165 WeakPolarHBondContact O-CB 3.2Å; Q161-W165 PolarHBondContact O-N 3.3Å; I163-W165 VanDerWaalsContact C-N 3.27Å; I163-W165 PolarHBondContact O-N 2.95Å; W165-H169 AromaticContact CE3-CD2 3.61Å; W165-H169 AromaticContact CZ3-CD2 3.83Å; W165-K170 HydrophobicContact CD2-CB 3.96Å; W165-K170 HydrophobicContact CE3-CB 4.47Å; W165-K170 HydrophobicContact CG-CB 4.27Å; W165-K170 HydrophobicContact CH2-CB 4.49Å; W165-K170 HydrophobicContact CZ2-CB 4.02Å; W165-K170 HydrophobicContact CZ2-CD 4.47Å; W165-K170 HydrophobicContact CZ2-CG 3.84Å; W165-K170 WeakPolarHBondContact O-CB 3.36Å; W165-K170 PolarHBondContact O-N 2.78Å; W165-C173 HydrophobicContact CH2-CB 4.23Å; W165-C173 HydrophobicContact CZ3-CB 3.92Å
166K91.1Very high88.3Confident164 Ų16472.4 Ų72.471%0.71334%0.344SS*.Iπ-helixtrans-67-37.1179.5-74.6176.1-179.1-1780112.1T162 I163 D164T162-K166 HydrophobicContact CG2-CD 4.4Å; T162-K166 WeakPolarHBondContact O-CG 3.49Å; T162-K166 PolarHBondContact O-N 3.02Å; T162-K166 VanDerWaalsContact O-N 3.1Å; I163-K166 PolarHBondContact O-N 2.77Å; D164-K166 PolarHBondContact O-N 3.37Å
167H84.8Confident86.4Confident98 Ų9876 Ų7645%0.45437%0.365SS..Iπ-helixtrans-88.8-51.1-171.5-74.9-94000113.6I163 D164I163-H167 PolarHBondContact O-CD2 2.81Å; I163-H167 VanDerWaalsContact O-CD2 3.23Å; I163-H167 PolarHBondContact O-N 2.97Å; I163-H167 VanDerWaalsContact O-N 3.16Å; D164-H167 PolarHBondContact O-N 3.24Å
168C85.3Confident84.5Confident23 Ų2381.3 Ų81.316%0.15540%0.399CS..Iπ-helixtrans-136-45.5-172.654.90000113.6D164 K170 K171 E172D164-C168 PolarHBondContact O-N 3.03Å; D164-C168 PolarHBondContact OD1-SG 2.93Å; C168-K170 VanDerWaalsContact C-N 3.31Å; C168-K170 PolarHBondContact O-N 3.1Å; C168-K170 VanDerWaalsContact O-N 3.14Å; C168-K171 PolarHBondContact O-N 3.27Å; C168-E172 PolarHBondContact O-N 2.82Å
169H88.1Confident82.5Confident5 Ų579 Ų792%0.02340%0.401CS..Iπ-helixtrans-65.3-29.2-166.2-175.951.3000114.1C147 V153 Y155 D164 W165 K171 E172 C173C147-H169 PolarHBondContact SG-NE2 2.95Å; V153-H169 WeakPolarHBondContact CG2-NE2 3.18Å; Y155-H169 PolarHBondContact OH-CD2 2.85Å; D164-H169 PolarHBondContact O-N 2.89Å; D164-H169 WeakPolarHBondContact OD2-CB 3.44Å; D164-H169 IonicContact OD2-CG 3.97Å; W165-H169 AromaticContact CE3-CD2 3.61Å; W165-H169 AromaticContact CZ3-CD2 3.83Å; H169-K171 PolarHBondContact O-N 2.77Å; H169-K171 VanDerWaalsContact O-N 3.16Å; H169-E172 PolarHBondContact O-N 2.84Å; H169-E172 VanDerWaalsContact O-N 3.17Å; H169-C173 WeakPolarHBondContact O-CA 3.16Å; H169-C173 WeakPolarHBondContact O-CB 3.32Å; H169-C173 PolarHBondContact O-N 2.9Å
170K88.6Confident80.5Confident145 Ų14578.4 Ų78.463%0.6341%0.405SS*.Hα-helixtrans-56.9-31.9174.2179.6176.7179.1-175.50112.9W165 C168W165-K170 HydrophobicContact CD2-CB 3.96Å; W165-K170 HydrophobicContact CE3-CB 4.47Å; W165-K170 HydrophobicContact CG-CB 4.27Å; W165-K170 HydrophobicContact CH2-CB 4.49Å; W165-K170 HydrophobicContact CZ2-CB 4.02Å; W165-K170 HydrophobicContact CZ2-CD 4.47Å; W165-K170 HydrophobicContact CZ2-CG 3.84Å; W165-K170 WeakPolarHBondContact O-CB 3.36Å; W165-K170 PolarHBondContact O-N 2.78Å; C168-K170 VanDerWaalsContact C-N 3.31Å; C168-K170 PolarHBondContact O-N 3.1Å; C168-K170 VanDerWaalsContact O-N 3.14Å
171K86.4Confident78.6Confident160 Ų16083.5 Ų83.570%0.69645%0.447SS*.Hα-helixtrans-84.1-30.7-179.8-63.2177.6-176.91720112.5C168 H169 K175C168-K171 PolarHBondContact O-N 3.27Å; H169-K171 PolarHBondContact O-N 2.77Å; H169-K171 VanDerWaalsContact O-N 3.16Å; K171-K175 WeakPolarHBondContact O-CD 3.48Å; K171-K175 WeakPolarHBondContact O-CE 3.41Å; K171-K175 PolarHBondContact O-NZ 3.04Å
172E86.1Confident77Confident23 Ų2385.2 Ų85.211%0.10746%0.461CS..Hα-helixtrans-92.6-21.3-176.2-63.6168.5-17300113.6K137 C168 H169 C174 K175K137-E172 IonicContact NZ-OE2 3.26Å; K137-E172 PolarHBondContact NZ-OE2 3.11Å; C168-E172 PolarHBondContact O-N 2.82Å; H169-E172 PolarHBondContact O-N 2.84Å; H169-E172 VanDerWaalsContact O-N 3.17Å; E172-C174 PolarHBondContact O-N 2.75Å; E172-K175 WeakPolarHBondContact O-CB 3.49Å; E172-K175 PolarHBondContact O-N 3.48Å; E172-K175 VanDerWaalsContact O-O 3.05Å
173C87.5Confident75.8Confident18 Ų1887.9 Ų87.912%0.12248%0.479CS..THydrogen-bonded Turntrans-55.6128-173.9-176.50000111.2W165 H169 K175W165-C173 HydrophobicContact CH2-CB 4.23Å; W165-C173 HydrophobicContact CZ3-CB 3.92Å; H169-C173 WeakPolarHBondContact O-CA 3.16Å; H169-C173 WeakPolarHBondContact O-CB 3.32Å; H169-C173 PolarHBondContact O-N 2.9Å; C173-K175 PolarHBondContact O-N 2.98Å
174C83.9Confident75.2Confident95 Ų9587.1 Ų87.164%0.64248%0.478SS*.THydrogen-bonded Turntrans64.212-176.4-50.40000115.1E172E172-C174 PolarHBondContact O-N 2.75Å
175K78.4Confident74.8Confident132 Ų13289.6 Ų89.657%0.57450%0.495SS*.SBendtrans-112.3130.6171.1-53.8-179.2-172.3162.10107.8K171 E172 C173 V177K171-K175 WeakPolarHBondContact O-CD 3.48Å; K171-K175 WeakPolarHBondContact O-CE 3.41Å; K171-K175 PolarHBondContact O-NZ 3.04Å; E172-K175 WeakPolarHBondContact O-CB 3.49Å; E172-K175 PolarHBondContact O-N 3.48Å; E172-K175 VanDerWaalsContact O-O 3.05Å; C173-K175 PolarHBondContact O-N 2.98Å; K175-V177 HydrophobicContact CB-CG2 3.58Å; K175-V177 HydrophobicContact CD-CG2 4.39Å; K175-V177 PolarHBondContact O-N 3.33Å
176Q60.9Low74.8Confident207 Ų20787.3 Ų87.397%0.96749%0.486SS*.  trans-75.753.5173.8-64.5-177.2-6.400110.2
177V56.7Low74.8Confident85 Ų8581.3 Ų81.352%0.51546%0.462SS..PPolyproline II helixtrans-90.5131177.8-165.40000107.5K175 S179K175-V177 HydrophobicContact CB-CG2 3.58Å; K175-V177 HydrophobicContact CD-CG2 4.39Å; K175-V177 PolarHBondContact O-N 3.33Å; V177-S179 PolarHBondContact O-N 3.05Å
178P53.7Low75.3Confident110 Ų11077 Ų7771%0.71444%0.442SS*.PPolyproline II helixtrans-52.9134.8167-20.230.4000109.1S180P178-S180 PolarHBondContact O-N 3.12Å
179S53.4Low75.7Confident86 Ų8677.5 Ų77.560%0.60145%0.445SS*.PPolyproline II helixtrans-53117.3176.2-171.90000108.7V177V177-S179 PolarHBondContact O-N 3.05Å
180S50.7Low76Confident67 Ų6780.3 Ų80.347%0.46946%0.458SS..PPolyproline II helixtrans-67.9145169.851.40000108.8P178 V182P178-S180 PolarHBondContact O-N 3.12Å; S180-V182 PolarHBondContact O-N 2.84Å; S180-V182 WeakPolarHBondContact OG-CG2 3.45Å
181A54.8Low76.3Confident108 Ų10875 Ų7589%0.89344%0.436SS*.  trans-71.358.1179.500000111.7
182V59.3Low76.9Confident82 Ų8270 Ų7050%0.49742%0.415SS..PPolyproline II helixtrans-81.7127.1174.2-174.40000107.7S180 S184S180-V182 PolarHBondContact O-N 2.84Å; S180-V182 WeakPolarHBondContact OG-CG2 3.45Å; V182-S184 PolarHBondContact O-N 3.38Å
183P68.3Low77.5Confident115 Ų11569.1 Ų69.175%0.74741%0.412SS*.PPolyproline II helixtrans-54.2127.6174.6-25.634.1000110.9
184S78.6Confident77.9Confident34 Ų3470.1 Ų70.124%0.23842%0.417CS..PPolyproline II helixtrans-71.2129.4175.4173.50000109L138 V182 F186 L187L138-S184 VanDerWaalsContact CD1-OG 3.28Å; L138-S184 WeakPolarHBondContact CD1-OG 3.49Å; V182-S184 PolarHBondContact O-N 3.38Å; S184-F186 PolarHBondContact O-N 3.21Å; S184-F186 PolarHBondContact OG-N 3.33Å; S184-L187 PolarHBondContact OG-N 2.87Å
185P82.9Confident78.5Confident58 Ų5869 Ų6938%0.37741%0.407SS..SBendtrans-67.1-17174.432.2-39.7000112.3K82 I163K82-P185 PolarHBondContact NZ-O 3.21Å; I163-P185 HydrophobicContact CG2-CG 3.61Å
186F90.6Very high79.3Confident18 Ų1867.6 Ų67.68%0.07940%0.403CS..SBendtrans-91.4-41.8-176.7-174.3-101000112.3A56 K82 L138 C139 H160 I163 S184A56-F186 HydrophobicContact CB-CE1 3.86Å; A56-F186 HydrophobicContact CB-CE2 4.32Å; A56-F186 HydrophobicContact CB-CZ 3.75Å; K82-F186 HydrophobicContact CD-CD2 4.34Å; K82-F186 WeakPolarHBondContact CD-O 3.43Å; K82-F186 PolarHBondContact NZ-O 2.95Å; L138-F186 HydrophobicContact CD1-CB 4.24Å; L138-F186 HydrophobicContact CD2-CB 3.86Å; L138-F186 HydrophobicContact CD2-CD1 4.49Å; L138-F186 HydrophobicContact CD2-CG 4.14Å; L138-F186 HydrophobicContact CG-CB 3.97Å; L138-F186 HydrophobicContact CG-CD1 4.43Å; L138-F186 HydrophobicContact CG-CG 4.41Å; C139-F186 HydrophobicContact CB-CD1 3.96Å; C139-F186 HydrophobicContact CB-CE1 3.67Å; H160-F186 AromaticContact CE1-CE1 3.51Å; H160-F186 AromaticContact CE1-CZ 3.55Å; H160-F186 AromaticContact NE2-CD2 3.93Å; H160-F186 AromaticContact NE2-CE1 3.57Å; H160-F186 AromaticContact NE2-CE2 3.39Å; H160-F186 WeakPolarHBondContact NE2-CE2 3.39Å; H160-F186 AromaticContact NE2-CZ 3.19Å; H160-F186 WeakPolarHBondContact NE2-CZ 3.38Å; I163-F186 HydrophobicContact CD1-CD2 4.46Å; S184-F186 PolarHBondContact O-N 3.21Å; S184-F186 PolarHBondContact OG-N 3.33Å
187L92.8Very high80.9Confident38 Ų3862.9 Ų62.920%0.19939%0.39CS..SBendtrans-73.8148.2-178.2-58.1-179.9000111G30 K31 L138 S184G30-L187 WeakPolarHBondContact O-CD2 3.17Å; K31-L187 HydrophobicContact CG-CD1 4.01Å; K31-L187 HydrophobicContact CG-CD2 4.41Å; L138-L187 WeakPolarHBondContact O-CD2 3.49Å; L138-L187 WeakPolarHBondContact O-CG 3.31Å; S184-L187 PolarHBondContact OG-N 2.87Å
188F94Very high82.5Confident7 Ų759.9 Ų59.93%0.03137%0.37CS..PPolyproline II helixtrans-79.1160.4165.1-61.6-66.8000110.2G30 A56 F57 L58 C80 K82 E190 L304 V306 I313G30-F188 PolarHBondContact N-O 3.09Å; A56-F188 HydrophobicContact CB-CD2 4.45Å; A56-F188 HydrophobicContact CB-CE2 3.82Å; A56-F188 HydrophobicContact CB-CZ 4.41Å; F57-F188 VanDerWaalsContact O-CD2 3.26Å; F57-F188 WeakPolarHBondContact O-CD2 3.21Å; L58-F188 HydrophobicContact CD1-CD2 4.42Å; L58-F188 HydrophobicContact CD1-CE2 4.24Å; C80-F188 VanDerWaalsContact SG-CE2 3.58Å; K82-F188 HydrophobicContact CD-CE1 4.43Å; K82-F188 HydrophobicContact CD-CZ 4.2Å; K82-F188 HydrophobicContact CG-CZ 4.08Å; F188-E190 PolarHBondContact O-N 2.93Å; F188-L304 HydrophobicContact CB-CD2 3.94Å; F188-L304 HydrophobicContact CD1-CB 3.85Å; F188-L304 HydrophobicContact CD1-CD1 4.44Å; F188-L304 HydrophobicContact CD1-CD2 3.87Å; F188-L304 HydrophobicContact CD1-CG 4.25Å; F188-L304 HydrophobicContact CD2-CD2 4.26Å; F188-L304 HydrophobicContact CE1-CB 4.16Å; F188-L304 HydrophobicContact CE1-CD1 4.23Å; F188-L304 HydrophobicContact CE1-CD2 4.44Å; F188-L304 HydrophobicContact CG-CD2 3.77Å; F188-V306 HydrophobicContact CD1-CG2 4.41Å; F188-V306 HydrophobicContact CE1-CG2 3.95Å; F188-I313 HydrophobicContact CE1-CD1 4.07Å; F188-I313 HydrophobicContact CZ-CD1 3.9Å
189P93.2Very high84Confident35 Ų3563 Ų6323%0.22738%0.375CS..PPolyproline II helixtrans-50.1138.9169.6-25.836000111.1G29 L304 K305G29-P189 VanDerWaalsContact CA-O 3.32Å; G29-P189 WeakPolarHBondContact CA-O 3.44Å; P189-L304 WeakPolarHBondContact CD-O 3.4Å; P189-K305 HydrophobicContact CG-CB 4.09Å; P189-K305 HydrophobicContact CG-CD 3.82Å; P189-K305 HydrophobicContact CG-CG 3.94Å
190E94.7Very high84.6Confident63 Ų6365.9 Ų65.929%0.29438%0.379SS..  trans-97115.3-176.7-172.1170.3-117.900109.1N16 L19 K27 V28 F188N16-E190 PolarHBondContact ND2-OE2 3.11Å; L19-E190 HydrophobicContact CD1-CG 3.59Å; K27-E190 WeakPolarHBondContact CE-OE1 3.45Å; K27-E190 IonicContact NZ-OE1 3.96Å; K27-E190 PolarHBondContact NZ-OE1 2.8Å; V28-E190 WeakPolarHBondContact O-CA 3.32Å; F188-E190 PolarHBondContact O-N 2.93Å
191L96.5Very high84.9Confident33 Ų3370.4 Ų70.417%0.17339%0.393CS..EExtended strand (participates in β ladder)trans-138148.4-175.3-66168.1000110L11 E13 K27 V28L11-L191 HydrophobicContact CB-CB 4.39Å; L11-L191 HydrophobicContact CB-CD1 4.21Å; L11-L191 HydrophobicContact CD1-CD1 3.97Å; L11-L191 HydrophobicContact CD2-CB 4.44Å; E13-L191 HydrophobicContact CG-CD2 4.34Å; K27-L191 CarbonylContact C-O 3.53Å; K27-L191 VanDerWaalsContact CA-O 3.28Å; K27-L191 WeakPolarHBondContact CA-O 3.49Å; K27-L191 VanDerWaalsContact CB-O 3.28Å; K27-L191 WeakPolarHBondContact CB-O 3.49Å; V28-L191 PolarHBondContact N-O 2.9Å; V28-L191 PolarHBondContact O-N 2.79Å
192E97.7Very high84.2Confident55 Ų5574.6 Ų74.626%0.25739%0.391SS..EExtended strand (participates in β ladder)trans-74.9144.5173.1-173.6163.8-154.900110.4L11 E12 A14 L19 V194L11-E192 WeakPolarHBondContact CA-O 3.49Å; E12-E192 PolarHBondContact N-O 2.87Å; E12-E192 PolarHBondContact O-N 2.84Å; A14-E192 HydrophobicContact CB-CB 3.75Å; L19-E192 HydrophobicContact CD2-CB 4.02Å; L19-E192 HydrophobicContact CD2-CG 4.36Å; E192-V194 HydrophobicContact CG-CG2 4Å
193L98.2Very high83.3Confident6 Ų679.6 Ų79.63%0.03141%0.409CS..EExtended strand (participates in β ladder)trans-108.7101.5174177.769.1000109F10 L11 S26 M59 V61 V258 L259F10-L193 WeakPolarHBondContact O-CA 3.48Å; L11-L193 HydrophobicContact CD2-CB 4.42Å; L11-L193 HydrophobicContact CD2-CD1 3.98Å; S26-L193 VanDerWaalsContact CB-O 3.25Å; S26-L193 WeakPolarHBondContact CB-O 3.47Å; S26-L193 PolarHBondContact O-N 3.01Å; M59-L193 HydrophobicContact CE-CD2 3.43Å; M59-L193 VanDerWaalsContact CE-CD2 3.43Å; V61-L193 HydrophobicContact CG2-CD2 4.01Å; L193-V258 HydrophobicContact CD1-CG2 3.5Å; L193-V258 VanDerWaalsContact CD1-CG2 3.5Å; L193-L259 HydrophobicContact CD1-CB 4.21Å; L193-L259 HydrophobicContact CD2-CD2 4Å
194V97.3Very high81.7Confident38 Ų3882.4 Ų82.423%0.2341%0.412CS..EExtended strand (participates in β ladder)trans-93.2140.6179-176.50000109G9 F10 E12 E192G9-V194 CarbonylContact C-O 3.5Å; G9-V194 WeakPolarHBondContact CA-O 3.3Å; F10-V194 PolarHBondContact N-O 3.38Å; F10-V194 PolarHBondContact O-N 3.48Å; E12-V194 HydrophobicContact CB-CG2 4.33Å; E12-V194 HydrophobicContact CG-CG2 4.09Å; E192-V194 HydrophobicContact CG-CG2 4Å
195T96Very high79.7Confident71 Ų7186.3 Ų86.344%0.43644%0.439SS..EExtended strand (participates in β ladder)trans-117.1134.9-179.557.90000112.3L8 L259L8-T195 CarbonylContact O-C 3.57Å; L8-T195 WeakPolarHBondContact O-CA 3.38Å; T195-L259 HydrophobicContact CG2-CD2 4.35Å
196E94.9Very high77.4Confident103 Ų10388.3 Ų88.348%0.48146%0.455SS..EExtended strand (participates in β ladder)trans-126.9147.6177.7-57.9-173.1157.500110.3A7 L8 F10A7-E196 CarbonylContact C-O 3.49Å; A7-E196 VanDerWaalsContact CA-O 3.28Å; A7-E196 WeakPolarHBondContact CA-O 3.44Å; L8-E196 PolarHBondContact N-O 3.47Å; L8-E196 PolarHBondContact O-N 2.63Å; F10-E196 HydrophobicContact CD2-CG 4.38Å; F10-E196 HydrophobicContact CE2-CB 4.24Å; F10-E196 HydrophobicContact CE2-CG 4.38Å
197P93.8Very high74.8Confident109 Ų10995.9 Ų95.971%0.70849%0.49SS*.EExtended strand (participates in β ladder)trans-65.6138.8177.128.1-34.1000111.3E199P197-E199 PolarHBondContact O-N 2.94Å
198E91.3Very high72Confident21 Ų2199.8 Ų99.810%0.09852%0.516CS..PPolyproline II helixtrans-65.6119.6173.6-178.2171.6-139.100110.3V6 L8 H200 R250 R260V6-E198 HydrophobicContact CB-CB 4.07Å; V6-E198 WeakPolarHBondContact CB-OE2 3.48Å; V6-E198 WeakPolarHBondContact O-CB 3.39Å; V6-E198 PolarHBondContact O-N 3.37Å; L8-E198 HydrophobicContact CD1-CB 4.23Å; L8-E198 HydrophobicContact CD1-CG 4.25Å; L8-E198 HydrophobicContact CD2-CB 4.07Å; L8-E198 HydrophobicContact CD2-CG 4.33Å; L8-E198 HydrophobicContact CG-CB 3.95Å; L8-E198 HydrophobicContact CG-CG 4.41Å; E198-H200 PolarHBondContact O-N 3.46Å; E198-R250 WeakPolarHBondContact OE1-CD 3.16Å; E198-R260 IonicContact OE1-CZ 2.65Å; E198-R260 IonicContact OE1-NH1 3.8Å; E198-R260 PolarHBondContact OE1-NH1 3.36Å; E198-R260 VanDerWaalsContact OE1-NH1 3.1Å; E198-R260 IonicContact OE1-NH2 2.96Å; E198-R260 PolarHBondContact OE1-NH2 2.84Å; E198-R260 IonicContact OE2-CZ 2.65Å; E198-R260 IonicContact OE2-NH2 3.92Å; E198-R260 PolarHBondContact OE2-NH2 3.3Å
199E84.3Confident69.1Low175 Ų175106.4 Ų106.482%0.81856%0.557SS**PPolyproline II helixtrans-74118.6172.8-62.6-165.916400110.4P197 Q201P197-E199 PolarHBondContact O-N 2.94Å; E199-Q201 PolarHBondContact O-N 2.64Å
200H67.5Low66Low148 Ų148108.2 Ų108.269%0.68558%0.581SS**  trans-75.5109.6170-72.9-53.1000109.7E198 K202E198-H200 PolarHBondContact O-N 3.46Å; H200-K202 PolarHBondContact O-N 3.33Å
201Q56Low63Low161 Ų161113.5 Ų113.575%0.75261%0.612SS**  trans-58.3115.1159.5-67.2-175.11.800107.2E199 E203E199-Q201 PolarHBondContact O-N 2.64Å; Q201-E203 PolarHBondContact O-N 3.11Å
202K39.4Very low59.9Low196 Ų196116.6 Ų116.685%0.85264%0.642SS**  trans-58.9112.4168.8-69.7177.4-177.4172.90105.8H200 E204H200-K202 PolarHBondContact O-N 3.33Å; K202-E204 VanDerWaalsContact C-N 3.33Å; K202-E204 PolarHBondContact O-N 3.23Å
203E40.7Very low57.1Low188 Ų188122.9 Ų122.988%0.87967%0.672SS**  trans-58.6102.4168.4-69.6-176.617100106.7Q201 S205Q201-E203 PolarHBondContact O-N 3.11Å; E203-S205 PolarHBondContact O-N 3.11Å
204E34.9Very low53.9Low174 Ų174130.8 Ų130.881%0.81371%0.714SS**  trans-61.6107.5165.4-78.3-170.7162.700106.6K202 S206K202-E204 VanDerWaalsContact C-N 3.33Å; K202-E204 PolarHBondContact O-N 3.23Å; E204-S206 PolarHBondContact O-N 3.38Å
205S35.9Very low51.1Low115 Ų115136.2 Ų136.280%0.80474%0.742SS**  trans-66.382.6169.859.80000108.9E203 Q207E203-S205 PolarHBondContact O-N 3.11Å; S205-Q207 PolarHBondContact O-N 2.89Å; S205-Q207 VanDerWaalsContact O-N 3.14Å
206S35.7Very low48.4Very low101 Ų101139.3 Ų139.371%0.70676%0.76SS**  trans-84.784.6175.9-58.90000109.8E204 T208E204-S206 PolarHBondContact O-N 3.38Å; S206-T208 PolarHBondContact O-N 3.35Å
207Q35.6Very low45.8Very low176 Ų176143.3 Ų143.382%0.82278%0.779SS**  trans-73.6107.4158.3-80.5179.8-12.300109.6S205S205-Q207 PolarHBondContact O-N 2.89Å; S205-Q207 VanDerWaalsContact O-N 3.14Å
208T34Very low43Very low121 Ų121142.7 Ų142.774%0.74278%0.776SS**  trans49.5123.1138.264.50000121.4S206S206-T208 PolarHBondContact O-N 3.35Å
209V32.7Very low40.7Very low146 Ų146147.3 Ų147.389%0.88581%0.811SS**  146.9131106.4178.80000110.3
210G28.8Very low38.7Very low72 Ų72143.6 Ų143.674%0.74280%0.804SS**  trans151.294.9148.900000116.3
211D31.5Very low37.6Very low175 Ų175142.1 Ų142.194%0.93680%0.8SS**  trans-50140.1164.8-82-46000113.8
212A32.4Very low37.2Very low98 Ų98139.4 Ų139.481%0.8180%0.795SS**  trans-161.1127.114000000111
213Q38.5Very low37.3Very low187 Ų187136.2 Ų136.287%0.87479%0.787SS**  trans-54.2144.6176.9-76.5140.6-35.900113.8
214N31Very low37.6Very low171 Ų171133.3 Ų133.391%0.91478%0.777SS**  trans-156.6137.9133.6-99.9-27.1000112.8
215N38.3Very low38.4Very low153 Ų153130.2 Ų130.282%0.81877%0.766SS**  trans-89.5122-171-15013.2000109.7
216V38.1Very low39.5Very low135 Ų135126.5 Ų126.582%0.81874%0.742SS**  trans-149.7118.5159.6-175.60000109.3
217E41.3Very low40.5Very low188 Ų188127.4 Ų127.488%0.87974%0.735SS**  trans-70131.5170-72.4174.9144.200111.2
218C34.1Very low41.6Very low95 Ų95122.2 Ų122.264%0.64272%0.715SS**  trans-149.2106.7157.5-165.60000109.9S220C218-S220 PolarHBondContact O-N 2.85Å
219S44.4Very low42.8Very low119 Ų119122.1 Ų122.183%0.83271%0.707SS**THydrogen-bonded Turntrans-93.551.5-163.564.40000114.5
220S42.3Very low44.1Very low97 Ų97120.6 Ų120.668%0.67869%0.693SS**THydrogen-bonded Turntrans-152.115173.7730000116.2C218C218-S220 PolarHBondContact O-N 2.85Å
221L43.8Very low45.5Very low116 Ų116123 Ų12361%0.60769%0.685SS**SBendtrans-119.27.3-179.2-57.6174.1000113.1
222V47.1Very low46.8Very low105 Ų105118 Ų11864%0.63666%0.658SS**Hα-helixtrans-88.1-14.3-169.8-66.40000114.3A226V222-A226 WeakPolarHBondContact O-CB 3.41Å; V222-A226 PolarHBondContact O-N 3.49Å
223D42.8Very low48Very low128 Ų128118.8 Ų118.868%0.68465%0.647SS**Hα-helixtrans-81.9-48.6179.3-104.8-7.7000112.1L225 A226 E227D223-L225 VanDerWaalsContact C-N 3.34Å; D223-L225 PolarHBondContact O-N 2.93Å; D223-A226 PolarHBondContact O-N 3.36Å; D223-E227 PolarHBondContact O-N 3.47Å
224D47.4Very low48.9Very low127 Ų127112.8 Ų112.868%0.67963%0.629SS**Hα-helixtrans-63.9-37.2-179.4-84.1-41.3000112.8T228D224-T228 PolarHBondContact O-N 2.65Å; D224-T228 VanDerWaalsContact O-N 3.11Å; D224-T228 PolarHBondContact O-OG1 2.96Å
225L51.2Low50.1Low110 Ų110106.3 Ų106.358%0.57659%0.593SS**Hα-helixtrans-71.9-36.6177-80.3164.2000111.9D223 T228 E229D223-L225 VanDerWaalsContact C-N 3.34Å; D223-L225 PolarHBondContact O-N 2.93Å; L225-T228 WeakPolarHBondContact CA-OG1 3.46Å; L225-T228 PolarHBondContact O-OG1 3.34Å; L225-E229 WeakPolarHBondContact O-CB 3.32Å; L225-E229 WeakPolarHBondContact O-CG 3.47Å; L225-E229 PolarHBondContact O-N 3.48Å
226A57.6Low50.9Low36 Ų36103.7 Ų103.730%0.29858%0.576SS.*Hα-helixtrans-70.6-41.1177.200000111.4V222 D223 E229 L230V222-A226 WeakPolarHBondContact O-CB 3.41Å; V222-A226 PolarHBondContact O-N 3.49Å; D223-A226 PolarHBondContact O-N 3.36Å; A226-E229 PolarHBondContact O-N 2.99Å; A226-L230 WeakPolarHBondContact O-CB 3.36Å; A226-L230 VanDerWaalsContact O-CD1 3.29Å; A226-L230 WeakPolarHBondContact O-CD1 3.32Å; A226-L230 VanDerWaalsContact O-CG 3.26Å; A226-L230 WeakPolarHBondContact O-CG 3.01Å; A226-L230 PolarHBondContact O-N 2.84Å
227E56.9Low52Low120 Ų120105.4 Ų105.456%0.56158%0.575SS**Hα-helixtrans-64.2-45175.6-74.2-170164.300111.7D223 E229 L230 E231D223-E227 PolarHBondContact O-N 3.47Å; E227-E229 PolarHBondContact O-N 2.91Å; E227-L230 PolarHBondContact O-N 3.02Å; E227-E231 WeakPolarHBondContact O-CB 3.4Å; E227-E231 WeakPolarHBondContact O-CG 3.48Å; E227-E231 PolarHBondContact O-N 3.26Å
228T59.8Low53.8Low67 Ų67100 Ų10041%0.41156%0.556SS.*Hα-helixtrans-65.7-35.3174.633.10000112.9D224 L225 N232D224-T228 PolarHBondContact O-N 2.65Å; D224-T228 VanDerWaalsContact O-N 3.11Å; D224-T228 PolarHBondContact O-OG1 2.96Å; L225-T228 WeakPolarHBondContact CA-OG1 3.46Å; L225-T228 PolarHBondContact O-OG1 3.34Å; T228-N232 VanDerWaalsContact O-CB 3.23Å; T228-N232 WeakPolarHBondContact O-CB 3.42Å; T228-N232 PolarHBondContact O-N 3.14Å; T228-N232 PolarHBondContact O-ND2 2.85Å
229E59.8Low56Low119 Ų119101.4 Ų101.456%0.55655%0.553SS**Hα-helixtrans-68.7-42.3172.8-82.6-174.5147.800112.3L225 A226 E227 N232 M233L225-E229 WeakPolarHBondContact O-CB 3.32Å; L225-E229 WeakPolarHBondContact O-CG 3.47Å; L225-E229 PolarHBondContact O-N 3.48Å; A226-E229 PolarHBondContact O-N 2.99Å; E227-E229 PolarHBondContact O-N 2.91Å; E229-N232 PolarHBondContact O-N 2.74Å; E229-M233 WeakPolarHBondContact O-CB 3.19Å; E229-M233 WeakPolarHBondContact O-CG 3.33Å; E229-M233 PolarHBondContact O-N 2.64Å
230L58.5Low57.8Low115 Ų11596.9 Ų96.960%0.60252%0.519SS*.Hα-helixtrans-64.5-42.7177-81.4155.8000111.7A226 E227 M233 A234A226-L230 WeakPolarHBondContact O-CB 3.36Å; A226-L230 VanDerWaalsContact O-CD1 3.29Å; A226-L230 WeakPolarHBondContact O-CD1 3.32Å; A226-L230 VanDerWaalsContact O-CG 3.26Å; A226-L230 WeakPolarHBondContact O-CG 3.01Å; A226-L230 PolarHBondContact O-N 2.84Å; E227-L230 PolarHBondContact O-N 3.02Å; L230-M233 PolarHBondContact O-N 3.41Å; L230-A234 WeakPolarHBondContact O-CB 3.21Å; L230-A234 PolarHBondContact O-N 3.02Å
231E59.7Low59.7Low121 Ų12192.4 Ų92.457%0.56549%0.488SS*.Hα-helixtrans-64-44172.7-76.2-175.3165.300111.5E227 M233 A234 M235E227-E231 WeakPolarHBondContact O-CB 3.4Å; E227-E231 WeakPolarHBondContact O-CG 3.48Å; E227-E231 PolarHBondContact O-N 3.26Å; E231-M233 VanDerWaalsContact C-N 3.31Å; E231-M233 PolarHBondContact O-N 2.94Å; E231-A234 PolarHBondContact O-N 3.11Å; E231-M235 VanDerWaalsContact O-CB 3.3Å; E231-M235 WeakPolarHBondContact O-CB 3.42Å; E231-M235 WeakPolarHBondContact O-CG 3.21Å; E231-M235 PolarHBondContact O-N 2.94Å
232N58Low61.7Low71 Ų7191.6 Ų91.638%0.3848%0.48SS..Hα-helixtrans-63.8-36.5177.2-78.1-40.5000112.4T228 E229 Q236 Q245T228-N232 VanDerWaalsContact O-CB 3.23Å; T228-N232 WeakPolarHBondContact O-CB 3.42Å; T228-N232 PolarHBondContact O-N 3.14Å; T228-N232 PolarHBondContact O-ND2 2.85Å; E229-N232 PolarHBondContact O-N 2.74Å; N232-Q236 WeakPolarHBondContact O-CB 3.49Å; N232-Q236 WeakPolarHBondContact O-CG 3.35Å; N232-Q236 PolarHBondContact O-N 3.14Å; N232-Q245 PolarHBondContact O-NE2 3.27Å; N232-Q245 VanDerWaalsContact O-NE2 3.11Å
233M58.1Low63.6Low115 Ų11588.6 Ų88.657%0.56746%0.462SS*.Hα-helixtrans-68.3-47.2174-73.3179.7-171.700111.4E229 L230 E231 M235 Q236E229-M233 WeakPolarHBondContact O-CB 3.19Å; E229-M233 WeakPolarHBondContact O-CG 3.33Å; E229-M233 PolarHBondContact O-N 2.64Å; L230-M233 PolarHBondContact O-N 3.41Å; E231-M233 VanDerWaalsContact C-N 3.31Å; E231-M233 PolarHBondContact O-N 2.94Å; M233-M235 PolarHBondContact O-N 3.33Å; M233-Q236 PolarHBondContact O-N 3.16Å; M233-Q236 VanDerWaalsContact O-N 3.14Å
234A56.3Low65.8Low60 Ų6084.6 Ų84.650%0.49644%0.438SS..Hα-helixtrans-64.4-37178.200000112.7L230 E231 Q236 E237L230-A234 WeakPolarHBondContact O-CB 3.21Å; L230-A234 PolarHBondContact O-N 3.02Å; E231-A234 PolarHBondContact O-N 3.11Å; A234-Q236 VanDerWaalsContact C-N 3.31Å; A234-Q236 PolarHBondContact O-N 3.4Å; A234-E237 PolarHBondContact O-N 2.94Å
235M56.3Low67.6Low35 Ų3579.6 Ų79.617%0.17241%0.411CS..Hα-helixtrans-70.7-24.8174.7-68.7-173.691.500112.8E231 M233 E237 G241 F244E231-M235 VanDerWaalsContact O-CB 3.3Å; E231-M235 WeakPolarHBondContact O-CB 3.42Å; E231-M235 WeakPolarHBondContact O-CG 3.21Å; E231-M235 PolarHBondContact O-N 2.94Å; M233-M235 PolarHBondContact O-N 3.33Å; M235-E237 VanDerWaalsContact C-N 3.33Å; M235-G241 CarbonylContact O-C 3.6Å; M235-G241 VanDerWaalsContact O-C 3.24Å; M235-G241 WeakPolarHBondContact O-CA 3.25Å; M235-F244 HydrophobicContact CE-CD1 3.34Å; M235-F244 HydrophobicContact CE-CE1 3.79Å; M235-F244 HydrophobicContact CE-CG 4.39Å
236Q55.6Low69.4Low99 Ų9980.9 Ų80.946%0.46341%0.412SS..Hα-helixtrans-78.1-15.3178.4-81.217011.600113.9N232 M233 A234 K242 Q245N232-Q236 WeakPolarHBondContact O-CB 3.49Å; N232-Q236 WeakPolarHBondContact O-CG 3.35Å; N232-Q236 PolarHBondContact O-N 3.14Å; M233-Q236 PolarHBondContact O-N 3.16Å; M233-Q236 VanDerWaalsContact O-N 3.14Å; A234-Q236 VanDerWaalsContact C-N 3.31Å; A234-Q236 PolarHBondContact O-N 3.4Å; Q236-K242 WeakPolarHBondContact O-CE 3.2Å; Q236-Q245 VanDerWaalsContact CG-OE1 3.25Å
237E62.1Low71Confident170 Ų17079.4 Ų79.479%0.79440%0.399SS*.SBendtrans-75-24.8-178.6-67.1-168.9157.700113.4A234 M235A234-E237 PolarHBondContact O-N 2.94Å; M235-E237 VanDerWaalsContact C-N 3.33Å
238T78.2Confident72.6Confident76 Ų7677.6 Ų77.647%0.46639%0.389SS..SBendtrans-103.9146.9179.366.50000111.7D240 G241 K242T238-D240 PolarHBondContact O-N 2.96Å; T238-G241 PolarHBondContact O-N 2.9Å; T238-G241 PolarHBondContact OG1-N 2.84Å; T238-G241 VanDerWaalsContact OG1-N 3.1Å; T238-K242 PolarHBondContact O-N 2.87Å
239E79.6Confident74.1Confident124 Ų12483.7 Ų83.758%0.57940%0.404SS*.Hα-helixtrans-59.2-32.6172.9-70.5-61.2117.800111.6K242 V243E239-K242 PolarHBondContact O-N 2.96Å; E239-K242 IonicContact OE1-NZ 2.67Å; E239-K242 PolarHBondContact OE1-NZ 2.81Å; E239-V243 WeakPolarHBondContact O-CG2 3.36Å; E239-V243 PolarHBondContact O-N 2.84Å; E239-V243 VanDerWaalsContact O-N 3.15Å
240D83.3Confident75.5Confident23 Ų2382.9 Ų82.912%0.12340%0.396CS..Hα-helixtrans-65.8-47.9177.6-16261000112.8T238 K242 V243 F244 S271 S272 T344T238-D240 PolarHBondContact O-N 2.96Å; D240-K242 VanDerWaalsContact C-N 3.29Å; D240-K242 PolarHBondContact O-N 3.38Å; D240-V243 PolarHBondContact O-N 3.31Å; D240-V243 VanDerWaalsContact O-N 3.12Å; D240-F244 PolarHBondContact O-N 3.22Å; D240-S271 WeakPolarHBondContact OD1-CA 3.15Å; D240-S271 WeakPolarHBondContact OD1-CB 3.31Å; D240-S271 PolarHBondContact OD1-OG 3.34Å; D240-S272 WeakPolarHBondContact CA-OG 3.28Å; D240-S272 PolarHBondContact N-OG 2.78Å; D240-S272 PolarHBondContact OD1-N 3.17Å; D240-S272 PolarHBondContact OD1-OG 3.01Å; D240-T344 WeakPolarHBondContact OD2-CB 3.36Å; D240-T344 WeakPolarHBondContact OD2-CG2 3.39Å; D240-T344 PolarHBondContact OD2-OG1 3.16Å
241G82.1Confident77.1Confident4 Ų479.1 Ų79.14%0.04138%0.377CS..Hα-helixtrans-67.9-28.7179.400000112.9M235 T238 F244 Q245M235-G241 CarbonylContact O-C 3.6Å; M235-G241 VanDerWaalsContact O-C 3.24Å; M235-G241 WeakPolarHBondContact O-CA 3.25Å; T238-G241 PolarHBondContact O-N 2.9Å; T238-G241 PolarHBondContact OG1-N 2.84Å; T238-G241 VanDerWaalsContact OG1-N 3.1Å; G241-F244 PolarHBondContact O-N 3.15Å; G241-Q245 WeakPolarHBondContact O-CB 3.21Å; G241-Q245 VanDerWaalsContact O-CG 3.3Å; G241-Q245 WeakPolarHBondContact O-CG 3.23Å; G241-Q245 PolarHBondContact O-N 3.45Å
242K85.4Confident78.6Confident98 Ų9876.7 Ų76.743%0.42638%0.377SS..Hα-helixtrans-63.7-44.5168.5-66.9175.5-166.8165.60112.2Q236 T238 E239 D240 Q245 K246Q236-K242 WeakPolarHBondContact O-CE 3.2Å; T238-K242 PolarHBondContact O-N 2.87Å; E239-K242 PolarHBondContact O-N 2.96Å; E239-K242 IonicContact OE1-NZ 2.67Å; E239-K242 PolarHBondContact OE1-NZ 2.81Å; D240-K242 VanDerWaalsContact C-N 3.29Å; D240-K242 PolarHBondContact O-N 3.38Å; K242-Q245 PolarHBondContact O-N 2.81Å; K242-K246 WeakPolarHBondContact O-CB 3.45Å; K242-K246 PolarHBondContact O-N 3.43Å
243V87.8Confident80.1Confident42 Ų4275.8 Ų75.826%0.25538%0.376SS..Hα-helixtrans-63.1-45176.71720000110.4E239 D240 K246 F247 W269E239-V243 WeakPolarHBondContact O-CG2 3.36Å; E239-V243 PolarHBondContact O-N 2.84Å; E239-V243 VanDerWaalsContact O-N 3.15Å; D240-V243 PolarHBondContact O-N 3.31Å; D240-V243 VanDerWaalsContact O-N 3.12Å; V243-K246 WeakPolarHBondContact O-CB 3.33Å; V243-K246 PolarHBondContact O-N 3.24Å; V243-F247 PolarHBondContact O-N 3.04Å; V243-W269 HydrophobicContact CG1-CB 4.4Å; V243-W269 WeakPolarHBondContact CG1-O 3.24Å
244F88.6Confident81.8Confident44 Ų4474.2 Ų74.219%0.19337%0.367CS..Hα-helixtrans-66.4-38.4178.4-173.4-108.9000112.9M235 D240 G241 K246 F247 K248 V270 F343M235-F244 HydrophobicContact CE-CD1 3.34Å; M235-F244 HydrophobicContact CE-CE1 3.79Å; M235-F244 HydrophobicContact CE-CG 4.39Å; D240-F244 PolarHBondContact O-N 3.22Å; G241-F244 PolarHBondContact O-N 3.15Å; F244-K246 VanDerWaalsContact C-N 3.35Å; F244-F247 WeakPolarHBondContact O-CB 3.22Å; F244-F247 PolarHBondContact O-N 2.89Å; F244-K248 HydrophobicContact CD1-CD 4.02Å; F244-K248 HydrophobicContact CD1-CG 4.27Å; F244-K248 HydrophobicContact CE1-CD 3.48Å; F244-K248 VanDerWaalsContact CE1-CD 3.48Å; F244-K248 HydrophobicContact CE1-CG 3.98Å; F244-K248 HydrophobicContact CZ-CD 3.92Å; F244-K248 HydrophobicContact CZ-CG 4.11Å; F244-K248 WeakPolarHBondContact O-CG 3.16Å; F244-K248 PolarHBondContact O-N 2.91Å; F244-V270 HydrophobicContact CD2-CB 4.46Å; F244-V270 WeakPolarHBondContact CD2-O 3.25Å; F244-F343 HydrophobicContact CD2-CD1 4.38Å; F244-F343 AromaticContact CE2-CD1 3.71Å; F244-F343 HydrophobicContact CE2-CD1 3.71Å; F244-F343 AromaticContact CE2-CE1 3.71Å; F244-F343 HydrophobicContact CE2-CE1 3.71Å
245Q85.7Confident83.5Confident23 Ų2374.4 Ų74.411%0.10736%0.363CS..Hα-helixtrans-64-40.1172.3-78.4-177.34.200111.8N232 Q236 G241 K242 F247 K248 R249N232-Q245 PolarHBondContact O-NE2 3.27Å; N232-Q245 VanDerWaalsContact O-NE2 3.11Å; Q236-Q245 VanDerWaalsContact CG-OE1 3.25Å; G241-Q245 WeakPolarHBondContact O-CB 3.21Å; G241-Q245 VanDerWaalsContact O-CG 3.3Å; G241-Q245 WeakPolarHBondContact O-CG 3.23Å; G241-Q245 PolarHBondContact O-N 3.45Å; K242-Q245 PolarHBondContact O-N 2.81Å; Q245-F247 VanDerWaalsContact C-N 3.32Å; Q245-K248 PolarHBondContact O-N 2.84Å; Q245-R249 WeakPolarHBondContact O-CB 3.45Å; Q245-R249 PolarHBondContact O-N 3.08Å
246K88.9Confident85.3Confident136 Ų13678.8 Ų78.859%0.59138%0.383SS*.Hα-helixtrans-62.2-41.9173.7-176.5-177.9178.9-177.60111.2K242 V243 F244 R250K242-K246 WeakPolarHBondContact O-CB 3.45Å; K242-K246 PolarHBondContact O-N 3.43Å; V243-K246 WeakPolarHBondContact O-CB 3.33Å; V243-K246 PolarHBondContact O-N 3.24Å; F244-K246 VanDerWaalsContact C-N 3.35Å; K246-R250 WeakPolarHBondContact O-CB 3.42Å; K246-R250 PolarHBondContact O-N 3.02Å
247F91.3Very high87.2Confident5 Ų574.2 Ų74.22%0.02236%0.362CS..Hα-helixtrans-57.8-57172.7176.2-86.7000110.7V243 F244 Q245 R249 R250 I251 L268 V270 M297 P298V243-F247 PolarHBondContact O-N 3.04Å; F244-F247 WeakPolarHBondContact O-CB 3.22Å; F244-F247 PolarHBondContact O-N 2.89Å; Q245-F247 VanDerWaalsContact C-N 3.32Å; F247-R249 PolarHBondContact O-N 3.36Å; F247-R250 PolarHBondContact O-N 3.12Å; F247-R250 VanDerWaalsContact O-N 3.07Å; F247-I251 HydrophobicContact CD1-CD1 4.05Å; F247-I251 HydrophobicContact CD1-CG1 4.45Å; F247-I251 HydrophobicContact CE1-CD1 3.47Å; F247-I251 VanDerWaalsContact CE1-CD1 3.47Å; F247-I251 HydrophobicContact CE1-CG1 4.25Å; F247-I251 HydrophobicContact CE1-CG2 4.38Å; F247-I251 HydrophobicContact CE2-CG2 4.45Å; F247-I251 HydrophobicContact CZ-CD1 4.11Å; F247-I251 HydrophobicContact CZ-CG2 4.21Å; F247-I251 WeakPolarHBondContact O-CG1 3.5Å; F247-I251 PolarHBondContact O-N 3.11Å; F247-L268 HydrophobicContact CD2-CD2 3.57Å; F247-L268 HydrophobicContact CD2-CG 3.66Å; F247-L268 HydrophobicContact CE2-CD2 3.95Å; F247-L268 HydrophobicContact CE2-CG 4.3Å; F247-L268 HydrophobicContact CG-CD2 4.24Å; F247-L268 HydrophobicContact CG-CG 4.45Å; F247-V270 HydrophobicContact CD1-CG1 4.19Å; F247-V270 HydrophobicContact CD2-CG1 3.66Å; F247-V270 HydrophobicContact CE1-CG1 4Å; F247-V270 HydrophobicContact CE2-CG1 3.48Å; F247-V270 VanDerWaalsContact CE2-CG1 3.48Å; F247-V270 HydrophobicContact CG-CG1 4.05Å; F247-V270 HydrophobicContact CZ-CG1 3.67Å; F247-M297 HydrophobicContact CE2-CE 3.79Å; F247-M297 HydrophobicContact CZ-CE 3.72Å; F247-P298 HydrophobicContact CZ-CG 4.25Å
248K89.9Confident88.9Confident82 Ų8266.1 Ų66.136%0.35732%0.324SS..Hα-helixtrans-54.5-47.9179.5-75.2-166-73.5-172.80112.1F244 Q245 R250 I251 A252F244-K248 HydrophobicContact CD1-CD 4.02Å; F244-K248 HydrophobicContact CD1-CG 4.27Å; F244-K248 HydrophobicContact CE1-CD 3.48Å; F244-K248 VanDerWaalsContact CE1-CD 3.48Å; F244-K248 HydrophobicContact CE1-CG 3.98Å; F244-K248 HydrophobicContact CZ-CD 3.92Å; F244-K248 HydrophobicContact CZ-CG 4.11Å; F244-K248 WeakPolarHBondContact O-CG 3.16Å; F244-K248 PolarHBondContact O-N 2.91Å; Q245-K248 PolarHBondContact O-N 2.84Å; K248-R250 VanDerWaalsContact C-N 3.31Å; K248-R250 PolarHBondContact O-N 3.12Å; K248-I251 WeakPolarHBondContact O-CG1 3.42Å; K248-I251 PolarHBondContact O-N 2.78Å; K248-A252 WeakPolarHBondContact O-CB 3.26Å; K248-A252 PolarHBondContact O-N 3.43Å
249R90.4Very high89.8Confident195 Ų19562.5 Ų62.574%0.73630%0.302SS*.Hα-helixtrans-61.7-40.1178.6-170.7-175.4-60.3175.21.1111.9Q245 F247 A252Q245-R249 WeakPolarHBondContact O-CB 3.45Å; Q245-R249 PolarHBondContact O-N 3.08Å; F247-R249 PolarHBondContact O-N 3.36Å; R249-A252 PolarHBondContact O-N 2.98Å
250R89.9Confident90.7Very high103 Ų10357.1 Ų57.139%0.38928%0.276SS..Hα-helixtrans-68.6-36.5-179.7-179.158.865.385.91.3112.4E198 K246 F247 K248 L268E198-R250 WeakPolarHBondContact OE1-CD 3.16Å; K246-R250 WeakPolarHBondContact O-CB 3.42Å; K246-R250 PolarHBondContact O-N 3.02Å; F247-R250 PolarHBondContact O-N 3.12Å; F247-R250 VanDerWaalsContact O-N 3.07Å; K248-R250 VanDerWaalsContact C-N 3.31Å; K248-R250 PolarHBondContact O-N 3.12Å; R250-L268 HydrophobicContact CB-CD1 4.11Å; R250-L268 HydrophobicContact CB-CD2 3.88Å; R250-L268 HydrophobicContact CG-CD1 4.11Å; R250-L268 HydrophobicContact CG-CD2 3.77Å
251I91.9Very high91.3Very high36 Ų3657.8 Ų57.819%0.18528%0.277CS..Hα-helixtrans-85.8-12.3179.666.2164.3000113.2F247 K248 S253 E254 P255 L268 M297F247-I251 HydrophobicContact CD1-CD1 4.05Å; F247-I251 HydrophobicContact CD1-CG1 4.45Å; F247-I251 HydrophobicContact CE1-CD1 3.47Å; F247-I251 VanDerWaalsContact CE1-CD1 3.47Å; F247-I251 HydrophobicContact CE1-CG1 4.25Å; F247-I251 HydrophobicContact CE1-CG2 4.38Å; F247-I251 HydrophobicContact CE2-CG2 4.45Å; F247-I251 HydrophobicContact CZ-CD1 4.11Å; F247-I251 HydrophobicContact CZ-CG2 4.21Å; F247-I251 WeakPolarHBondContact O-CG1 3.5Å; F247-I251 PolarHBondContact O-N 3.11Å; K248-I251 WeakPolarHBondContact O-CG1 3.42Å; K248-I251 PolarHBondContact O-N 2.78Å; I251-S253 PolarHBondContact O-N 3.05Å; I251-E254 CarbonylContact O-C 3.55Å; I251-E254 PolarHBondContact O-N 2.9Å; I251-P255 WeakPolarHBondContact O-CA 3.23Å; I251-P255 VanDerWaalsContact O-N 3.11Å; I251-L268 HydrophobicContact CG2-CD2 3.9Å; I251-M297 HydrophobicContact CG2-CE 3.65Å
252A91Very high92Very high69 Ų6960.8 Ų60.857%0.5729%0.29SS*.THydrogen-bonded Turntrans-61.3-29.9-173.500000114K248 R249K248-A252 WeakPolarHBondContact O-CB 3.26Å; K248-A252 PolarHBondContact O-N 3.43Å; R249-A252 PolarHBondContact O-N 2.98Å
253S90.1Very high92.4Very high52 Ų5259.4 Ų59.436%0.36428%0.282SS..THydrogen-bonded Turntrans-68.2-38.2175.157.60000112I251I251-S253 PolarHBondContact O-N 3.05Å
254E93.5Very high92.6Very high82 Ų8262.2 Ų62.238%0.38330%0.295SS..  trans-134.570.8-174.7-66.5-56.515400110.8L8 F10 I251 H256 Q257L8-E254 HydrophobicContact CD1-CB 3.9Å; L8-E254 HydrophobicContact CD1-CG 3.83Å; F10-E254 HydrophobicContact CE1-CB 4.35Å; F10-E254 HydrophobicContact CZ-CB 4.25Å; F10-E254 HydrophobicContact CZ-CG 4.29Å; I251-E254 CarbonylContact O-C 3.55Å; I251-E254 PolarHBondContact O-N 2.9Å; E254-H256 PolarHBondContact O-N 3.37Å; E254-Q257 WeakPolarHBondContact O-CB 3.49Å; E254-Q257 WeakPolarHBondContact O-CG 3.46Å; E254-Q257 PolarHBondContact O-N 2.98Å; E254-Q257 PolarHBondContact O-NE2 2.54Å
255P92.8Very high92.8Very high64 Ų6461.1 Ų61.142%0.41630%0.296SS..THydrogen-bonded Turntrans-68.2-20.9-173.426.8-35000113.3I251 Q257I251-P255 WeakPolarHBondContact O-CA 3.23Å; I251-P255 VanDerWaalsContact O-N 3.11Å; P255-Q257 VanDerWaalsContact C-N 3.28Å; P255-Q257 PolarHBondContact O-N 3.45Å
256H93.1Very high93Very high128 Ų12864.2 Ų64.259%0.59332%0.32SS*.THydrogen-bonded Turntrans-82-0.5-179.5-65.5-67.4000114.1E254 V258E254-H256 PolarHBondContact O-N 3.37Å; H256-V258 PolarHBondContact O-N 3.15Å
257Q95.4Very high93.2Very high2 Ų258.4 Ų58.41%0.00930%0.297CS..  trans-63.1127.817968.9-171.2-78.500111.9L8 G9 F10 E254 P255 M297 Q299L8-Q257 HydrophobicContact CB-CB 4.49Å; G9-Q257 CarbonylContact O-C 3.08Å; G9-Q257 WeakPolarHBondContact O-CA 3.44Å; F10-Q257 HydrophobicContact CE1-CB 4.09Å; F10-Q257 HydrophobicContact CZ-CB 4.49Å; E254-Q257 WeakPolarHBondContact O-CB 3.49Å; E254-Q257 WeakPolarHBondContact O-CG 3.46Å; E254-Q257 PolarHBondContact O-N 2.98Å; E254-Q257 PolarHBondContact O-NE2 2.54Å; P255-Q257 VanDerWaalsContact C-N 3.28Å; P255-Q257 PolarHBondContact O-N 3.45Å; Q257-M297 HydrophobicContact CG-CE 4.43Å; Q257-M297 HydrophobicContact CG-CG 4.2Å; Q257-M297 VanDerWaalsContact O-CB 3.22Å; Q257-M297 WeakPolarHBondContact O-CB 3.37Å; Q257-Q299 WeakPolarHBondContact O-CB 3.44Å
258V97.4Very high93.3Very high1 Ų159.2 Ų59.21%0.00630%0.301CS..  trans-103.3-17.5179-61.90000113.1G9 L11 L193 H256 M297 Q299 L300G9-V258 WeakPolarHBondContact O-CG2 3.34Å; G9-V258 PolarHBondContact O-N 2.73Å; L11-V258 HydrophobicContact CD1-CG1 4.04Å; L11-V258 HydrophobicContact CD1-CG2 4.44Å; L11-V258 HydrophobicContact CD2-CG2 3.84Å; L11-V258 HydrophobicContact CG-CB 4.48Å; L11-V258 HydrophobicContact CG-CG1 4.05Å; L11-V258 HydrophobicContact CG-CG2 3.79Å; L193-V258 HydrophobicContact CD1-CG2 3.5Å; L193-V258 VanDerWaalsContact CD1-CG2 3.5Å; H256-V258 PolarHBondContact O-N 3.15Å; V258-M297 PolarHBondContact O-N 3.47Å; V258-Q299 HydrophobicContact CG1-CG 4.28Å; V258-L300 HydrophobicContact CB-CB 4.09Å; V258-L300 HydrophobicContact CB-CD1 4.23Å; V258-L300 HydrophobicContact CG1-CB 4.21Å; V258-L300 HydrophobicContact CG1-CD1 4.29Å
259L98.1Very high93.5Very high0 Ų057 Ų570%029%0.291CS..EExtended strand (participates in β ladder)trans-137.5146.2179.6-173.288.8000109.6L8 G9 M59 V61 L193 T195 F294 Q295L8-L259 CarbonylContact C-O 3.49Å; L8-L259 WeakPolarHBondContact CA-O 3.4Å; G9-L259 PolarHBondContact N-O 2.99Å; G9-L259 PolarHBondContact O-N 2.96Å; M59-L259 HydrophobicContact CE-CD1 3.89Å; V61-L259 HydrophobicContact CG1-CD2 4.43Å; V61-L259 HydrophobicContact CG2-CD1 4.09Å; V61-L259 HydrophobicContact CG2-CD2 4.28Å; L193-L259 HydrophobicContact CD1-CB 4.21Å; L193-L259 HydrophobicContact CD2-CD2 4Å; T195-L259 HydrophobicContact CG2-CD2 4.35Å; L259-F294 HydrophobicContact CD1-CB 4.23Å; L259-F294 HydrophobicContact CD1-CD2 3.39Å; L259-F294 HydrophobicContact CD1-CE2 3.88Å; L259-F294 HydrophobicContact CD1-CG 3.96Å; L259-Q295 CarbonylContact C-O 3.56Å; L259-Q295 WeakPolarHBondContact CA-O 3.4Å
260R97.4Very high93.5Very high10 Ų1047.8 Ų47.84%0.03826%0.256CS..EExtended strand (participates in β ladder)trans-127.1114.2159.7-55.7175.664.899.7-2.1109.2V6 A7 L8 E198 F294 Q295 M297V6-R260 HydrophobicContact CG1-CB 4.06Å; A7-R260 CarbonylContact O-C 3.44Å; A7-R260 WeakPolarHBondContact O-CA 3.25Å; L8-R260 HydrophobicContact CD2-CG 3.9Å; E198-R260 IonicContact OE1-CZ 2.65Å; E198-R260 IonicContact OE1-NH1 3.8Å; E198-R260 PolarHBondContact OE1-NH1 3.36Å; E198-R260 VanDerWaalsContact OE1-NH1 3.1Å; E198-R260 IonicContact OE1-NH2 2.96Å; E198-R260 PolarHBondContact OE1-NH2 2.84Å; E198-R260 IonicContact OE2-CZ 2.65Å; E198-R260 IonicContact OE2-NH2 3.92Å; E198-R260 PolarHBondContact OE2-NH2 3.3Å; R260-F294 CarbonylContact O-C 3.16Å; R260-F294 VanDerWaalsContact O-CA 3.31Å; R260-F294 WeakPolarHBondContact O-CA 3.34Å; R260-F294 WeakPolarHBondContact O-CB 3.16Å; R260-Q295 HydrophobicContact CB-CG 3.68Å; R260-Q295 HydrophobicContact CG-CG 4.31Å; R260-Q295 PolarHBondContact N-O 3.41Å; R260-Q295 PolarHBondContact O-N 2.97Å; R260-M297 HydrophobicContact CG-CG 4.2Å; R260-M297 HydrophobicContact CG-SD 3.88Å
261Y97.4Very high93.5Very high37 Ų3743 Ų4315%0.14524%0.238CC..EExtended strand (participates in β ladder)trans-96.8121.9-179.6-172.8-84.2000110A7 V61 A63 R263 E293 F294A7-Y261 PolarHBondContact N-O 2.75Å; A7-Y261 PolarHBondContact O-N 3.31Å; V61-Y261 HydrophobicContact CG1-CD2 4.24Å; V61-Y261 HydrophobicContact CG1-CE2 4.41Å; A63-Y261 HydrophobicContact CB-CE2 3.8Å; A63-Y261 WeakPolarHBondContact CB-OH 3.39Å; Y261-R263 HydrophobicContact CE1-CB 4.34Å; Y261-E293 HydrophobicContact CE2-CG 4.03Å; Y261-E293 PolarHBondContact OH-OE1 3.4Å; Y261-E293 VanDerWaalsContact OH-OE1 3.13Å; Y261-F294 HydrophobicContact CD2-CB 3.75Å; Y261-F294 HydrophobicContact CD2-CD1 4.13Å; Y261-F294 HydrophobicContact CD2-CG 4.35Å; Y261-F294 HydrophobicContact CE2-CD1 4.29Å; Y261-F294 HydrophobicContact CG-CB 4.31Å
262F95.5Very high93.3Very high68 Ų6843.7 Ų43.730%0.29825%0.246SC..  trans-15980.2178.9-174-144000110.8V6 G265 F292 E293V6-F262 HydrophobicContact CG1-CB 4.47Å; V6-F262 HydrophobicContact CG2-CB 4.12Å; V6-F262 HydrophobicContact CG2-CD1 4.03Å; V6-F262 HydrophobicContact CG2-CD2 4.36Å; V6-F262 HydrophobicContact CG2-CG 3.93Å; F262-G265 VanDerWaalsContact CD1-CA 3.45Å; F262-G265 VanDerWaalsContact CE1-CA 3.42Å; F262-G265 WeakPolarHBondContact O-CA 2.83Å; F262-G265 PolarHBondContact O-N 3.04Å; F262-F292 HydrophobicContact CB-CE1 4.23Å; F262-F292 WeakPolarHBondContact O-CD1 3.43Å; F262-F292 WeakPolarHBondContact O-CE1 3.33Å; F262-E293 CarbonylContact C-O 3.24Å; F262-E293 VanDerWaalsContact C-O 3.26Å; F262-E293 PolarHBondContact N-O 2.97Å
263R94.3Very high93.1Very high69 Ų6945.3 Ų45.326%0.2624%0.242SC..THydrogen-bonded Turntrans-63.6135.7-176.2-172.9176.6-171.2-91.30112.2Y261 G265 I291 F292 E293 A324Y261-R263 HydrophobicContact CE1-CB 4.34Å; R263-G265 PolarHBondContact O-N 2.91Å; R263-I291 HydrophobicContact CG-CD1 4.17Å; R263-F292 WeakPolarHBondContact CA-O 3.3Å; R263-E293 WeakPolarHBondContact CD-OE1 3.12Å; R263-E293 WeakPolarHBondContact CD-OE2 3.46Å; R263-E293 PolarHBondContact N-O 3.15Å; R263-E293 IonicContact NE-OE1 2.77Å; R263-E293 IonicContact NE-OE2 3.41Å; R263-E293 PolarHBondContact NE-OE2 2.95Å; R263-A324 PolarHBondContact NH2-O 3.12Å
264D92.9Very high92.9Very high100 Ų10046 Ų4654%0.53524%0.239SC..THydrogen-bonded Turntrans62.114.5-172.3-152.234.5000113.9R289 I291 F292D264-R289 IonicContact OD1-NH2 3.83Å; D264-I291 HydrophobicContact CB-CD1 3.99Å; D264-F292 PolarHBondContact N-O 2.74Å
265G91.3Very high92.7Very high21 Ų2144.8 Ų44.822%0.21624%0.237CC..SBendtrans-92.2-159.2175.700000114F262 R263 F292F262-G265 VanDerWaalsContact CD1-CA 3.45Å; F262-G265 VanDerWaalsContact CE1-CA 3.42Å; F262-G265 WeakPolarHBondContact O-CA 2.83Å; F262-G265 PolarHBondContact O-N 3.04Å; R263-G265 PolarHBondContact O-N 2.91Å; G265-F292 WeakPolarHBondContact O-CB 3.2Å
266S90.6Very high92.4Very high88 Ų8842.6 Ų42.662%0.61522%0.224SC*.  trans-121.7137.8176.262.10000111.6
267P93.6Very high91.8Very high15 Ų1541.8 Ų41.810%0.09723%0.227CC..  trans-64.2149.8172.2-17.529.1000112.7W269 F292 A319P267-W269 HydrophobicContact CB-CD2 4.08Å; P267-W269 HydrophobicContact CB-CE3 4.39Å; P267-W269 HydrophobicContact CB-CH2 4.01Å; P267-W269 HydrophobicContact CB-CZ2 3.64Å; P267-W269 HydrophobicContact CB-CZ3 4.36Å; P267-W269 HydrophobicContact CG-CH2 3.87Å; P267-W269 HydrophobicContact CG-CZ2 3.4Å; P267-F292 HydrophobicContact CB-CE2 4.05Å; P267-F292 HydrophobicContact CB-CZ 4.21Å; P267-F292 HydrophobicContact CG-CD1 4.48Å; P267-F292 HydrophobicContact CG-CD2 3.55Å; P267-F292 HydrophobicContact CG-CE1 4.46Å; P267-F292 HydrophobicContact CG-CE2 3.53Å; P267-F292 HydrophobicContact CG-CG 4.03Å; P267-F292 HydrophobicContact CG-CZ 4Å; P267-A319 HydrophobicContact CB-CB 4.2Å; P267-A319 HydrophobicContact CG-CB 3.83Å
268L93.1Very high90.7Very high21 Ų2149.8 Ų49.811%0.1126%0.264CS..  trans-85.4104.3164.4-17375.6000108.5F247 R250 I251F247-L268 HydrophobicContact CD2-CD2 3.57Å; F247-L268 HydrophobicContact CD2-CG 3.66Å; F247-L268 HydrophobicContact CE2-CD2 3.95Å; F247-L268 HydrophobicContact CE2-CG 4.3Å; F247-L268 HydrophobicContact CG-CD2 4.24Å; F247-L268 HydrophobicContact CG-CG 4.45Å; R250-L268 HydrophobicContact CB-CD1 4.11Å; R250-L268 HydrophobicContact CB-CD2 3.88Å; R250-L268 HydrophobicContact CG-CD1 4.11Å; R250-L268 HydrophobicContact CG-CD2 3.77Å; I251-L268 HydrophobicContact CG2-CD2 3.9Å
269W94.3Very high89.6Confident36 Ų3659.3 Ų59.314%0.13631%0.306CS..  trans-83.1146.8-178.2-59111.7000112.3V243 P267 V275 P276 T317 A319 W339 Q341V243-W269 HydrophobicContact CG1-CB 4.4Å; V243-W269 WeakPolarHBondContact CG1-O 3.24Å; P267-W269 HydrophobicContact CB-CD2 4.08Å; P267-W269 HydrophobicContact CB-CE3 4.39Å; P267-W269 HydrophobicContact CB-CH2 4.01Å; P267-W269 HydrophobicContact CB-CZ2 3.64Å; P267-W269 HydrophobicContact CB-CZ3 4.36Å; P267-W269 HydrophobicContact CG-CH2 3.87Å; P267-W269 HydrophobicContact CG-CZ2 3.4Å; W269-V275 HydrophobicContact CB-CG2 4.27Å; W269-V275 HydrophobicContact CD2-CG1 4.42Å; W269-V275 HydrophobicContact CD2-CG2 4.11Å; W269-V275 HydrophobicContact CG-CG2 3.85Å; W269-V275 HydrophobicContact CZ2-CG1 4.23Å; W269-P276 HydrophobicContact CH2-CG 3.76Å; W269-P276 HydrophobicContact CZ2-CG 3.73Å; W269-T317 HydrophobicContact CE3-CG2 3.7Å; W269-T317 HydrophobicContact CZ3-CG2 3.99Å; W269-A319 HydrophobicContact CH2-CB 3.72Å; W269-A319 HydrophobicContact CZ3-CB 4.14Å; W269-W339 AromaticContact CH2-CD1 3.78Å; W269-W339 HydrophobicContact CH2-CG 4.47Å; W269-W339 AromaticContact CZ3-CD1 3.78Å; W269-Q341 HydrophobicContact CE3-CB 4.24Å; W269-Q341 HydrophobicContact CZ3-CB 4.25Å
270V90.9Very high88.8Confident1 Ų161.2 Ų61.21%0.00633%0.326CS..SBendtrans-86.9-20.9175.3-63.40000112.3F244 F247 Q341 F343F244-V270 HydrophobicContact CD2-CB 4.46Å; F244-V270 WeakPolarHBondContact CD2-O 3.25Å; F247-V270 HydrophobicContact CD1-CG1 4.19Å; F247-V270 HydrophobicContact CD2-CG1 3.66Å; F247-V270 HydrophobicContact CE1-CG1 4Å; F247-V270 HydrophobicContact CE2-CG1 3.48Å; F247-V270 VanDerWaalsContact CE2-CG1 3.48Å; F247-V270 HydrophobicContact CG-CG1 4.05Å; F247-V270 HydrophobicContact CZ-CG1 3.67Å; V270-Q341 HydrophobicContact CG2-CG 3.96Å; V270-F343 HydrophobicContact CB-CD1 3.89Å; V270-F343 HydrophobicContact CB-CE1 3.88Å; V270-F343 HydrophobicContact CG1-CD1 4.1Å; V270-F343 HydrophobicContact CG1-CE1 3.57Å; V270-F343 HydrophobicContact CG1-CZ 4.29Å; V270-F343 HydrophobicContact CG2-CD1 4.09Å; V270-F343 HydrophobicContact CG2-CE1 4.36Å
271S89.6Confident88.6Confident3 Ų361.9 Ų61.92%0.02133%0.329CS..  trans-138.1151.5-177.6172.30000110.8D240 E273 Q341 T344D240-S271 WeakPolarHBondContact OD1-CA 3.15Å; D240-S271 WeakPolarHBondContact OD1-CB 3.31Å; D240-S271 PolarHBondContact OD1-OG 3.34Å; S271-E273 WeakPolarHBondContact OG-CB 3.42Å; S271-E273 PolarHBondContact OG-N 2.65Å; S271-Q341 PolarHBondContact O-NE2 2.77Å; S271-T344 WeakPolarHBondContact OG-CG2 3.28Å
272S86.3Confident88.4Confident51 Ų5162.9 Ų62.936%0.35734%0.34SS..SBendtrans-72.7-19.3169660000112.5D240D240-S272 WeakPolarHBondContact CA-OG 3.28Å; D240-S272 PolarHBondContact N-OG 2.78Å; D240-S272 PolarHBondContact OD1-N 3.17Å; D240-S272 PolarHBondContact OD1-OG 3.01Å
273E86.9Confident88.5Confident103 Ų10365.7 Ų65.748%0.48135%0.354SS..SBendtrans-86.4156.5177.8-57-172.5161.600111.5R89 S271 V275 Q341R89-E273 IonicContact NH2-OE2 2.99Å; R89-E273 PolarHBondContact NH2-OE2 2.89Å; S271-E273 WeakPolarHBondContact OG-CB 3.42Å; S271-E273 PolarHBondContact OG-N 2.65Å; E273-V275 PolarHBondContact O-N 3.47Å; E273-V275 VanDerWaalsContact O-N 3.09Å; E273-Q341 PolarHBondContact O-NE2 3.17Å
274H87.6Confident88.5Confident65 Ų6562.7 Ų62.730%0.30134%0.344SS..SBendtrans55.130.8174.4-160.969.5000114.6N90 W339 K340N90-H274 HydrophobicContact CB-CB 4.41Å; N90-H274 WeakPolarHBondContact CB-CD2 3.45Å; N90-H274 WeakPolarHBondContact CB-NE2 3.49Å; N90-H274 VanDerWaalsContact CG-CG 3.41Å; N90-H274 WeakPolarHBondContact ND2-CB 3.33Å; N90-H274 PolarHBondContact O-CE1 2.71Å; N90-H274 PolarHBondContact O-NE2 3.36Å; N90-H274 PolarHBondContact OD1-CD2 3.21Å; H274-W339 AromaticContact CD2-CE2 3.66Å; H274-W339 AromaticContact CD2-CZ2 3.67Å; H274-W339 AromaticContact CD2-NE1 3.36Å; H274-W339 PolarHBondContact CD2-NE1 3.46Å; H274-W339 AromaticContact CE1-CE2 3.95Å; H274-W339 AromaticContact CE1-CH2 3.83Å; H274-W339 AromaticContact CE1-CZ2 3.32Å; H274-W339 WeakPolarHBondContact CE1-CZ2 3.1Å; H274-W339 AromaticContact CG-CZ2 3.96Å; H274-W339 AromaticContact ND1-CZ2 3.76Å; H274-W339 AromaticContact NE2-CE2 3.37Å; H274-W339 AromaticContact NE2-CZ2 3.24Å; H274-W339 WeakPolarHBondContact NE2-CZ2 3.28Å; H274-W339 AromaticContact NE2-NE1 3.53Å; H274-W339 WeakPolarHBondContact O-CZ2 3.21Å; H274-W339 PolarHBondContact O-NE1 3.02Å; H274-K340 PolarHBondContact CD2-O 2.94Å; H274-K340 PolarHBondContact NE2-O 2.85Å
275V87.9Confident88.5Confident57 Ų5762.4 Ų62.435%0.34535%0.35SS..PPolyproline II helixtrans-80129.6167.1177.20000108.2W269 E273 V277W269-V275 HydrophobicContact CB-CG2 4.27Å; W269-V275 HydrophobicContact CD2-CG1 4.42Å; W269-V275 HydrophobicContact CD2-CG2 4.11Å; W269-V275 HydrophobicContact CG-CG2 3.85Å; W269-V275 HydrophobicContact CZ2-CG1 4.23Å; E273-V275 PolarHBondContact O-N 3.47Å; E273-V275 VanDerWaalsContact O-N 3.09Å; V275-V277 PolarHBondContact O-N 3.34Å
276P86.5Confident88.7Confident19 Ų1964.2 Ų64.212%0.12336%0.359CS..PPolyproline II helixtrans-67.5129.3-177.726.3-30.7000110.6W269 I281 Y321 W339W269-P276 HydrophobicContact CH2-CG 3.76Å; W269-P276 HydrophobicContact CZ2-CG 3.73Å; P276-I281 HydrophobicContact CB-CG1 4.31Å; P276-Y321 VanDerWaalsContact CG-OH 3.31Å; P276-Y321 WeakPolarHBondContact CG-OH 3.38Å; P276-W339 HydrophobicContact CB-CD2 3.86Å; P276-W339 HydrophobicContact CB-CE3 4Å; P276-W339 HydrophobicContact CB-CG 4.43Å; P276-W339 HydrophobicContact CB-CH2 4.11Å; P276-W339 HydrophobicContact CB-CZ2 3.97Å; P276-W339 HydrophobicContact CB-CZ3 4.13Å; P276-W339 HydrophobicContact CG-CD2 4.07Å; P276-W339 HydrophobicContact CG-CG 4.13Å
277V81.9Confident88.8Confident110 Ų11062.3 Ų62.367%0.66735%0.352SS*.PPolyproline II helixtrans-77.7149.3165-169.10000107.9V275 K279 G280V275-V277 PolarHBondContact O-N 3.34Å; V277-K279 PolarHBondContact O-N 3.34Å; V277-G280 WeakPolarHBondContact O-CA 3.31Å; V277-G280 PolarHBondContact O-N 3.48Å
278E72.3Confident88.9Confident170 Ų17062.3 Ų62.379%0.79435%0.353SS*.G310 helixtrans-49.4-35.6-178.4-68.8-171.4154.700113.9G280 I281E278-G280 VanDerWaalsContact C-N 3.26Å; E278-G280 PolarHBondContact O-N 2.88Å; E278-I281 PolarHBondContact O-N 3.46Å
279K72.7Confident89Confident202 Ų20267.7 Ų67.788%0.87837%0.372SS*.G310 helixtrans-70.3-18.1176.9-66.5-176.6179.3178.10114.5V277 I281V277-K279 PolarHBondContact O-N 3.34Å; K279-I281 VanDerWaalsContact C-N 3.32Å
280G81.6Confident89.1Confident40 Ų4067.5 Ų67.541%0.41237%0.371SS..G310 helixtrans-80.2-12.9178.200000113.5V277 E278V277-G280 WeakPolarHBondContact O-CA 3.31Å; V277-G280 PolarHBondContact O-N 3.48Å; E278-G280 VanDerWaalsContact C-N 3.26Å; E278-G280 PolarHBondContact O-N 2.88Å
281I92.8Very high89.4Confident23 Ų2367.8 Ų67.812%0.11837%0.373CS..SBendtrans-94.5116.7178.4-59.7162.4000108.5P276 E278 K279 R290 Y321 F337P276-I281 HydrophobicContact CB-CG1 4.31Å; E278-I281 PolarHBondContact O-N 3.46Å; K279-I281 VanDerWaalsContact C-N 3.32Å; I281-R290 HydrophobicContact CG2-CB 3.86Å; I281-Y321 HydrophobicContact CD1-CD1 3.62Å; I281-Y321 HydrophobicContact CD1-CE1 3.33Å; I281-Y321 HydrophobicContact CD1-CE2 4.47Å; I281-Y321 HydrophobicContact CD1-CG 4.32Å; I281-Y321 HydrophobicContact CG1-CD1 4.41Å; I281-Y321 HydrophobicContact CG1-CE1 4.34Å; I281-Y321 HydrophobicContact CG2-CD1 4.39Å; I281-Y321 HydrophobicContact CG2-CG 4.35Å; I281-F337 HydrophobicContact CG1-CD1 4.49Å; I281-F337 HydrophobicContact CG1-CE1 4.21Å; I281-F337 HydrophobicContact CG2-CD1 3.97Å; I281-F337 HydrophobicContact CG2-CE1 4.4Å
282P94.9Very high89.7Confident58 Ų5868.1 Ų68.138%0.37737%0.373SS..PPolyproline II helixtrans-67.1147.3-179.725.8-32000111.3R290 F337P282-R290 PolarHBondContact O-NH1 3.05Å; P282-F337 HydrophobicContact CG-CD2 3.58Å; P282-F337 HydrophobicContact CG-CE2 3.87Å; P282-F337 HydrophobicContact CG-CG 4.08Å
283H95.8Very high90.3Very high128 Ų12865.7 Ų65.759%0.59336%0.356SS*.PPolyproline II helixtrans-64.5153.4173-75-134.7000111.2G287 R290H283-G287 PolarHBondContact ND1-O 3.2Å; H283-R290 VanDerWaalsContact C-NH1 3.31Å; H283-R290 PolarHBondContact O-NH1 3.21Å
284C95.9Very high90.8Very high5 Ų560.8 Ų60.83%0.03433%0.334CS..PPolyproline II helixtrans-62.5157.6169.8-171.70000110.3C286 G287 S288 R290 C323C284-C286 PolarHBondContact O-N 3.18Å; C284-C286 VanDerWaalsContact O-N 3.13Å; C284-G287 PolarHBondContact O-N 2.93Å; C284-S288 WeakPolarHBondContact CB-O 3.15Å; C284-S288 PolarHBondContact N-O 3.33Å; C284-R290 HydrophobicContact CB-CG 4.4Å; C284-C323 HydrophobicContact CB-CB 4.05Å
285S92.8Very high91.3Very high94 Ų9457.8 Ų57.866%0.65732%0.32SS*.THydrogen-bonded Turntrans-58.8-23.6176.253.30000113.7G287S285-G287 VanDerWaalsContact C-N 3.28Å
286C94.1Very high91.8Very high60 Ų6055.1 Ų55.141%0.40530%0.303SS..THydrogen-bonded Turntrans-79.1-6.4173.168.90000114.2C284 C327C284-C286 PolarHBondContact O-N 3.18Å; C284-C286 VanDerWaalsContact O-N 3.13Å; C286-C327 HydrophobicContact CB-CB 3.73Å; C286-C327 WeakPolarHBondContact SG-CB 3.24Å; C286-C327 VanDerWaalsContact SG-SG 3.63Å
287G94.5Very high92.3Very high47 Ų4754.3 Ų54.349%0.48530%0.298SS..SBendtrans95.3-15.5-176.800000115.2H283 C284 S285H283-G287 PolarHBondContact ND1-O 3.2Å; C284-G287 PolarHBondContact O-N 2.93Å; S285-G287 VanDerWaalsContact C-N 3.28Å
288S95.1Very high92.8Very high16 Ų1650.1 Ų50.111%0.11227%0.273CS..PPolyproline II helixtrans-64.6150.8175.1174.80000111.8C284 D325C284-S288 WeakPolarHBondContact CB-O 3.15Å; C284-S288 PolarHBondContact N-O 3.33Å; S288-D325 WeakPolarHBondContact CB-OD2 3.27Å; S288-D325 PolarHBondContact OG-OD2 3.24Å
289R95.7Very high93.9Very high134 Ų13444.3 Ų44.351%0.50625%0.246SC..PPolyproline II helixtrans-61.6154.8166.269.4-177.9-175.6114.57.2110.9D264 I291 A324D264-R289 IonicContact OD1-NH2 3.83Å; R289-I291 HydrophobicContact CG-CG2 4.5Å; R289-A324 HydrophobicContact CG-CB 4.03Å; R289-A324 WeakPolarHBondContact O-CB 3.32Å; R289-A324 PolarHBondContact O-N 2.98Å
290R96.2Very high94.9Very high31 Ų3134.7 Ų34.712%0.11720%0.204CC..EExtended strand (participates in β ladder)trans-96.9140.7166.2-65.4-174.4172.1102.2-5.5109.6I281 P282 H283 C284 T322 S335 E336I281-R290 HydrophobicContact CG2-CB 3.86Å; P282-R290 PolarHBondContact O-NH1 3.05Å; H283-R290 VanDerWaalsContact C-NH1 3.31Å; H283-R290 PolarHBondContact O-NH1 3.21Å; C284-R290 HydrophobicContact CB-CG 4.4Å; R290-T322 CarbonylContact C-O 3.55Å; R290-T322 WeakPolarHBondContact CA-O 3.24Å; R290-T322 WeakPolarHBondContact CB-O 3.4Å; R290-S335 PolarHBondContact NH2-O 3.47Å; R290-E336 IonicContact CZ-OE2 3.61Å; R290-E336 IonicContact NE-OE2 2.89Å; R290-E336 PolarHBondContact NE-OE2 3.26Å
291I96.3Very high95.4Very high8 Ų834.2 Ų34.24%0.04119%0.192CC..EExtended strand (participates in β ladder)trans-115.4156.5176.858.7174.1000109.5R263 D264 R289 Y321 T322 A324R263-I291 HydrophobicContact CG-CD1 4.17Å; D264-I291 HydrophobicContact CB-CD1 3.99Å; R289-I291 HydrophobicContact CG-CG2 4.5Å; I291-Y321 CarbonylContact O-C 3.47Å; I291-Y321 WeakPolarHBondContact O-CA 3.49Å; I291-T322 PolarHBondContact N-O 3.49Å; I291-T322 PolarHBondContact O-N 3.48Å; I291-A324 HydrophobicContact CD1-CB 4.34Å; I291-A324 HydrophobicContact CG1-CB 4.31Å; I291-A324 HydrophobicContact CG2-CB 3.89Å
292F96.9Very high95.3Very high9 Ų938.4 Ų38.44%0.03922%0.215CC..EExtended strand (participates in β ladder)trans-61.2138.8174.1175.4-113.7000110.4F262 R263 D264 G265 P267 F294 Q295 A319 Y321F262-F292 HydrophobicContact CB-CE1 4.23Å; F262-F292 WeakPolarHBondContact O-CD1 3.43Å; F262-F292 WeakPolarHBondContact O-CE1 3.33Å; R263-F292 WeakPolarHBondContact CA-O 3.3Å; D264-F292 PolarHBondContact N-O 2.74Å; G265-F292 WeakPolarHBondContact O-CB 3.2Å; P267-F292 HydrophobicContact CB-CE2 4.05Å; P267-F292 HydrophobicContact CB-CZ 4.21Å; P267-F292 HydrophobicContact CG-CD1 4.48Å; P267-F292 HydrophobicContact CG-CD2 3.55Å; P267-F292 HydrophobicContact CG-CE1 4.46Å; P267-F292 HydrophobicContact CG-CE2 3.53Å; P267-F292 HydrophobicContact CG-CG 4.03Å; P267-F292 HydrophobicContact CG-CZ 4Å; F292-F294 WeakPolarHBondContact CE2-O 3.28Å; F292-Q295 HydrophobicContact CE2-CB 4.09Å; F292-Q295 HydrophobicContact CZ-CB 4Å; F292-Q295 HydrophobicContact CZ-CG 4.26Å; F292-A319 HydrophobicContact CD2-CB 4.31Å; F292-A319 HydrophobicContact CE2-CB 4.08Å; F292-Y321 HydrophobicContact CB-CD1 4.14Å; F292-Y321 HydrophobicContact CB-CE1 3.9Å
293E97.6Very high95Very high0 Ų038.1 Ų38.10%021%0.21CC..EExtended strand (participates in β ladder)trans-114.7-59178.8-168.288.4-17900111.3R74 I76 Y261 F262 R263 V320 T322R74-E293 IonicContact CZ-OE1 3.49Å; R74-E293 VanDerWaalsContact CZ-OE1 3.26Å; R74-E293 IonicContact CZ-OE2 3.21Å; R74-E293 IonicContact NH1-OE1 3.93Å; R74-E293 PolarHBondContact NH1-OE1 3.24Å; R74-E293 IonicContact NH2-OE1 3.33Å; R74-E293 PolarHBondContact NH2-OE1 3.26Å; R74-E293 IonicContact NH2-OE2 2.99Å; R74-E293 PolarHBondContact NH2-OE2 3.43Å; I76-E293 HydrophobicContact CD1-CG 3.6Å; Y261-E293 HydrophobicContact CE2-CG 4.03Å; Y261-E293 PolarHBondContact OH-OE1 3.4Å; Y261-E293 VanDerWaalsContact OH-OE1 3.13Å; F262-E293 CarbonylContact C-O 3.24Å; F262-E293 VanDerWaalsContact C-O 3.26Å; F262-E293 PolarHBondContact N-O 2.97Å; R263-E293 WeakPolarHBondContact CD-OE1 3.12Å; R263-E293 WeakPolarHBondContact CD-OE2 3.46Å; R263-E293 PolarHBondContact N-O 3.15Å; R263-E293 IonicContact NE-OE1 2.77Å; R263-E293 IonicContact NE-OE2 3.41Å; R263-E293 PolarHBondContact NE-OE2 2.95Å; E293-V320 PolarHBondContact N-O 3.02Å; E293-T322 HydrophobicContact CB-CG2 3.92Å; E293-T322 HydrophobicContact CG-CG2 4.14Å; E293-T322 PolarHBondContact OE2-OG1 2.83Å
294F98.3Very high94.5Very high0 Ų032.2 Ų32.20%018%0.183CC..EExtended strand (participates in β ladder)trans-156.5163.8-18064.1-102.9000110.3V61 I76 V78 L259 R260 Y261 F292 V296 V320V61-F294 HydrophobicContact CB-CE1 4.14Å; V61-F294 HydrophobicContact CB-CZ 4.48Å; V61-F294 HydrophobicContact CG2-CD1 4.43Å; V61-F294 HydrophobicContact CG2-CE1 3.98Å; V61-F294 HydrophobicContact CG2-CE2 4.27Å; V61-F294 HydrophobicContact CG2-CZ 3.88Å; I76-F294 HydrophobicContact CB-CE1 3.94Å; I76-F294 HydrophobicContact CB-CZ 4.41Å; I76-F294 HydrophobicContact CD1-CD1 4.24Å; I76-F294 HydrophobicContact CD1-CE1 3.72Å; I76-F294 HydrophobicContact CG1-CE1 4.47Å; I76-F294 HydrophobicContact CG2-CE1 3.74Å; I76-F294 HydrophobicContact CG2-CZ 3.89Å; V78-F294 HydrophobicContact CG2-CE2 4.4Å; V78-F294 HydrophobicContact CG2-CZ 4.12Å; L259-F294 HydrophobicContact CD1-CB 4.23Å; L259-F294 HydrophobicContact CD1-CD2 3.39Å; L259-F294 HydrophobicContact CD1-CE2 3.88Å; L259-F294 HydrophobicContact CD1-CG 3.96Å; R260-F294 CarbonylContact O-C 3.16Å; R260-F294 VanDerWaalsContact O-CA 3.31Å; R260-F294 WeakPolarHBondContact O-CA 3.34Å; R260-F294 WeakPolarHBondContact O-CB 3.16Å; Y261-F294 HydrophobicContact CD2-CB 3.75Å; Y261-F294 HydrophobicContact CD2-CD1 4.13Å; Y261-F294 HydrophobicContact CD2-CG 4.35Å; Y261-F294 HydrophobicContact CE2-CD1 4.29Å; Y261-F294 HydrophobicContact CG-CB 4.31Å; F292-F294 WeakPolarHBondContact CE2-O 3.28Å; F294-V296 HydrophobicContact CD2-CG2 4.3Å; F294-V296 HydrophobicContact CE2-CG2 3.94Å; F294-V320 HydrophobicContact CD1-CB 4.48Å; F294-V320 HydrophobicContact CD2-CB 4.12Å; F294-V320 HydrophobicContact CD2-CG2 4.05Å; F294-V320 HydrophobicContact CE1-CB 4.24Å; F294-V320 HydrophobicContact CE1-CG1 4.11Å; F294-V320 HydrophobicContact CE2-CB 3.88Å; F294-V320 HydrophobicContact CE2-CG1 4.46Å; F294-V320 HydrophobicContact CE2-CG2 3.47Å; F294-V320 VanDerWaalsContact CE2-CG2 3.47Å; F294-V320 HydrophobicContact CG-CB 4.43Å; F294-V320 HydrophobicContact CZ-CB 3.93Å; F294-V320 HydrophobicContact CZ-CG1 4.01Å; F294-V320 HydrophobicContact CZ-CG2 3.77Å; F294-V320 PolarHBondContact O-N 2.84Å
295Q97.6Very high93.5Very high3 Ų339 Ų391%0.01421%0.212CC..EExtended strand (participates in β ladder)trans-119.6144.6170.962.5-177.958.600111.8L259 R260 F292 M297 L318L259-Q295 CarbonylContact C-O 3.56Å; L259-Q295 WeakPolarHBondContact CA-O 3.4Å; R260-Q295 HydrophobicContact CB-CG 3.68Å; R260-Q295 HydrophobicContact CG-CG 4.31Å; R260-Q295 PolarHBondContact N-O 3.41Å; R260-Q295 PolarHBondContact O-N 2.97Å; F292-Q295 HydrophobicContact CE2-CB 4.09Å; F292-Q295 HydrophobicContact CZ-CB 4Å; F292-Q295 HydrophobicContact CZ-CG 4.26Å; Q295-M297 HydrophobicContact CG-SD 4.09Å; Q295-M297 PolarHBondContact NE2-SD 3.4Å; Q295-L318 CarbonylContact C-O 3.51Å; Q295-L318 WeakPolarHBondContact CA-O 3.44Å
296V98.3Very high92.3Very high0 Ų036.2 Ų36.20%019%0.191CC..EExtended strand (participates in β ladder)trans-96.1127.1170.7-170.60000108.2M59 F294 L300 W315 L318M59-V296 HydrophobicContact SD-CB 4.39Å; M59-V296 HydrophobicContact SD-CG1 3.93Å; M59-V296 HydrophobicContact SD-CG2 3.53Å; M59-V296 VanDerWaalsContact SD-CG2 3.53Å; F294-V296 HydrophobicContact CD2-CG2 4.3Å; F294-V296 HydrophobicContact CE2-CG2 3.94Å; V296-L300 HydrophobicContact CG1-CB 4.27Å; V296-L300 HydrophobicContact CG1-CD2 3.4Å; V296-L300 HydrophobicContact CG1-CG 4.46Å; V296-W315 HydrophobicContact CG1-CZ2 4.43Å; V296-L318 HydrophobicContact CB-CB 4.03Å; V296-L318 HydrophobicContact CB-CD1 4.34Å; V296-L318 HydrophobicContact CB-CG 4.43Å; V296-L318 HydrophobicContact CG2-CB 4.34Å; V296-L318 PolarHBondContact N-O 3.32Å; V296-L318 PolarHBondContact O-N 2.93Å; V296-L318 VanDerWaalsContact O-N 3.08Å
297M96.6Very high90.2Very high3 Ų340.2 Ų40.22%0.01521%0.208CC..  trans-83.7155.8-175.6-60-59.1-68.300110.8F247 I251 Q257 V258 R260 Q295 Q299 L300 W315F247-M297 HydrophobicContact CE2-CE 3.79Å; F247-M297 HydrophobicContact CZ-CE 3.72Å; I251-M297 HydrophobicContact CG2-CE 3.65Å; Q257-M297 HydrophobicContact CG-CE 4.43Å; Q257-M297 HydrophobicContact CG-CG 4.2Å; Q257-M297 VanDerWaalsContact O-CB 3.22Å; Q257-M297 WeakPolarHBondContact O-CB 3.37Å; V258-M297 PolarHBondContact O-N 3.47Å; R260-M297 HydrophobicContact CG-CG 4.2Å; R260-M297 HydrophobicContact CG-SD 3.88Å; Q295-M297 HydrophobicContact CG-SD 4.09Å; Q295-M297 PolarHBondContact NE2-SD 3.4Å; M297-Q299 PolarHBondContact O-N 3.44Å; M297-L300 WeakPolarHBondContact O-CB 3.39Å; M297-L300 PolarHBondContact O-N 2.9Å; M297-W315 PolarHBondContact O-NE1 2.83Å
298P93.6Very high88.3Confident22 Ų2240.8 Ų40.814%0.14321%0.205CC..THydrogen-bonded Turntrans-66.8-2617926.8-30.9000111.6F247 L300 L301 W315 G316 F343F247-P298 HydrophobicContact CZ-CG 4.25Å; P298-L300 PolarHBondContact O-N 3.28Å; P298-L300 VanDerWaalsContact O-N 3.08Å; P298-L301 VanDerWaalsContact O-CB 3.25Å; P298-L301 WeakPolarHBondContact O-CB 3.39Å; P298-L301 WeakPolarHBondContact O-CG 3.2Å; P298-L301 PolarHBondContact O-N 2.99Å; P298-W315 WeakPolarHBondContact CB-O 3.49Å; P298-G316 WeakPolarHBondContact CD-O 3.32Å; P298-G316 VanDerWaalsContact CG-O 3.31Å; P298-G316 WeakPolarHBondContact CG-O 3.49Å; P298-F343 HydrophobicContact CB-CE2 4.09Å; P298-F343 HydrophobicContact CB-CZ 3.96Å; P298-F343 HydrophobicContact CG-CZ 3.87Å
299Q93.7Very high86.1Confident48 Ų4846.3 Ų46.322%0.22424%0.24CC..THydrogen-bonded Turntrans-53.8-31.4177.7179.757.822.700113.2Q257 V258 M297 L301 N302Q257-Q299 WeakPolarHBondContact O-CB 3.44Å; V258-Q299 HydrophobicContact CG1-CG 4.28Å; M297-Q299 PolarHBondContact O-N 3.44Å; Q299-L301 PolarHBondContact O-N 2.94Å; Q299-L301 VanDerWaalsContact O-N 3.12Å; Q299-N302 PolarHBondContact NE2-ND2 2.92Å; Q299-N302 WeakPolarHBondContact O-CB 3.42Å; Q299-N302 PolarHBondContact O-N 3.14Å; Q299-N302 VanDerWaalsContact O-N 3.12Å; Q299-N302 PolarHBondContact OE1-ND2 3.23Å
300L95.1Very high83.8Confident0 Ų046.2 Ų46.20%025%0.25CC..Hα-helixtrans-54.7-32.7177.2-179.758.8000112.6L11 V28 L58 M59 V258 V296 M297 P298 N302 D303 L304 W315L11-L300 HydrophobicContact CD1-CD1 3.87Å; V28-L300 HydrophobicContact CB-CD1 4.44Å; V28-L300 HydrophobicContact CG1-CD1 3.85Å; V28-L300 HydrophobicContact CG2-CD1 3.79Å; L58-L300 HydrophobicContact CD1-CD2 4.1Å; L58-L300 HydrophobicContact CG-CD2 4.38Å; M59-L300 HydrophobicContact SD-CD2 4.19Å; V258-L300 HydrophobicContact CB-CB 4.09Å; V258-L300 HydrophobicContact CB-CD1 4.23Å; V258-L300 HydrophobicContact CG1-CB 4.21Å; V258-L300 HydrophobicContact CG1-CD1 4.29Å; V296-L300 HydrophobicContact CG1-CB 4.27Å; V296-L300 HydrophobicContact CG1-CD2 3.4Å; V296-L300 HydrophobicContact CG1-CG 4.46Å; M297-L300 WeakPolarHBondContact O-CB 3.39Å; M297-L300 PolarHBondContact O-N 2.9Å; P298-L300 PolarHBondContact O-N 3.28Å; P298-L300 VanDerWaalsContact O-N 3.08Å; L300-N302 PolarHBondContact O-N 2.88Å; L300-D303 PolarHBondContact O-N 2.91Å; L300-L304 HydrophobicContact CD1-CD2 4.37Å; L300-L304 HydrophobicContact CG-CD2 4.39Å; L300-L304 HydrophobicContact CG-CG 4.34Å; L300-L304 WeakPolarHBondContact O-CG 3.19Å; L300-L304 PolarHBondContact O-N 3.32Å; L300-W315 HydrophobicContact CB-CZ2 4.31Å; L300-W315 HydrophobicContact CD2-CZ2 4.22Å; L300-W315 HydrophobicContact CG-CZ2 4.42Å
301L91.8Very high81.9Confident30 Ų3045.6 Ų45.616%0.15725%0.251CS..Hα-helixtrans-57.1-34-178.8-67.7169000112.7P298 Q299 D303 L304 I313 W315P298-L301 VanDerWaalsContact O-CB 3.25Å; P298-L301 WeakPolarHBondContact O-CB 3.39Å; P298-L301 WeakPolarHBondContact O-CG 3.2Å; P298-L301 PolarHBondContact O-N 2.99Å; Q299-L301 PolarHBondContact O-N 2.94Å; Q299-L301 VanDerWaalsContact O-N 3.12Å; L301-D303 VanDerWaalsContact C-N 3.27Å; L301-D303 PolarHBondContact O-N 3.38Å; L301-L304 HydrophobicContact CD2-CD1 4.35Å; L301-L304 PolarHBondContact O-N 2.97Å; L301-I313 HydrophobicContact CD2-CB 4.48Å; L301-I313 HydrophobicContact CD2-CG2 3.79Å; L301-I313 WeakPolarHBondContact CD2-O 3.45Å; L301-W315 HydrophobicContact CD1-CD2 4.23Å; L301-W315 HydrophobicContact CD1-CG 4.48Å; L301-W315 HydrophobicContact CD2-CD2 3.89Å; L301-W315 HydrophobicContact CD2-CE3 3.67Å; L301-W315 HydrophobicContact CD2-CH2 3.3Å; L301-W315 HydrophobicContact CD2-CZ2 3.48Å; L301-W315 VanDerWaalsContact CD2-CZ2 3.48Å; L301-W315 HydrophobicContact CD2-CZ3 3.41Å; L301-W315 VanDerWaalsContact CD2-CZ3 3.41Å; L301-W315 HydrophobicContact CG-CD2 4.18Å; L301-W315 HydrophobicContact CG-CE3 4.45Å; L301-W315 HydrophobicContact CG-CH2 4.09Å; L301-W315 HydrophobicContact CG-CZ2 3.74Å; L301-W315 HydrophobicContact CG-CZ3 4.45Å
302N90.2Very high80.5Confident110 Ų11048.7 Ų48.759%0.58827%0.273SS*.Hα-helixtrans-66.9-30.8179.7-64.5-34000112Q299 L300Q299-N302 PolarHBondContact NE2-ND2 2.92Å; Q299-N302 WeakPolarHBondContact O-CB 3.42Å; Q299-N302 PolarHBondContact O-N 3.14Å; Q299-N302 VanDerWaalsContact O-N 3.12Å; Q299-N302 PolarHBondContact OE1-ND2 3.23Å; L300-N302 PolarHBondContact O-N 2.88Å
303D88.6Confident80Confident53 Ų5349 Ų4928%0.28328%0.275SS..Hα-helixtrans-87.9-16.7-177.5-60.3-65.7000113L11 L300 L301 K305L11-D303 HydrophobicContact CD1-CB 3.61Å; L300-D303 PolarHBondContact O-N 2.91Å; L301-D303 VanDerWaalsContact C-N 3.27Å; L301-D303 PolarHBondContact O-N 3.38Å; D303-K305 PolarHBondContact O-N 3.47Å
304L85.6Confident79.5Confident4 Ų452.7 Ų52.72%0.02130%0.295CS..THydrogen-bonded Turntrans-71.8-7.5179.7-64.8-179.8000113.6V28 L58 F188 P189 L300 L301 V306 W315V28-L304 HydrophobicContact CG1-CD2 3.87Å; L58-L304 HydrophobicContact CD1-CD1 3.66Å; L58-L304 HydrophobicContact CD1-CD2 3.78Å; L58-L304 HydrophobicContact CD1-CG 4.37Å; F188-L304 HydrophobicContact CB-CD2 3.94Å; F188-L304 HydrophobicContact CD1-CB 3.85Å; F188-L304 HydrophobicContact CD1-CD1 4.44Å; F188-L304 HydrophobicContact CD1-CD2 3.87Å; F188-L304 HydrophobicContact CD1-CG 4.25Å; F188-L304 HydrophobicContact CD2-CD2 4.26Å; F188-L304 HydrophobicContact CE1-CB 4.16Å; F188-L304 HydrophobicContact CE1-CD1 4.23Å; F188-L304 HydrophobicContact CE1-CD2 4.44Å; F188-L304 HydrophobicContact CG-CD2 3.77Å; P189-L304 WeakPolarHBondContact CD-O 3.4Å; L300-L304 HydrophobicContact CD1-CD2 4.37Å; L300-L304 HydrophobicContact CG-CD2 4.39Å; L300-L304 HydrophobicContact CG-CG 4.34Å; L300-L304 WeakPolarHBondContact O-CG 3.19Å; L300-L304 PolarHBondContact O-N 3.32Å; L301-L304 HydrophobicContact CD2-CD1 4.35Å; L301-L304 PolarHBondContact O-N 2.97Å; L304-V306 HydrophobicContact CB-CG2 3.5Å; L304-V306 PolarHBondContact O-N 2.9Å; L304-W315 HydrophobicContact CD1-CH2 3.8Å
305K75.3Confident79.3Confident148 Ų14852.7 Ų52.764%0.64330%0.295SS*.THydrogen-bonded Turntrans48.845.6179.8-61.8-176.6-175.9177.50112.5P189 D303 D307P189-K305 HydrophobicContact CG-CB 4.09Å; P189-K305 HydrophobicContact CG-CD 3.82Å; P189-K305 HydrophobicContact CG-CG 3.94Å; D303-K305 PolarHBondContact O-N 3.47Å; K305-D307 PolarHBondContact O-N 3.01Å
306V68.1Low79Confident35 Ų3552.6 Ų52.621%0.21229%0.294CS..  trans-86.554.5-179.3-164.60000108.7F188 L304 S308 A311 I313F188-V306 HydrophobicContact CD1-CG2 4.41Å; F188-V306 HydrophobicContact CE1-CG2 3.95Å; L304-V306 HydrophobicContact CB-CG2 3.5Å; L304-V306 PolarHBondContact O-N 2.9Å; V306-S308 VanDerWaalsContact C-N 3.25Å; V306-S308 PolarHBondContact O-N 2.86Å; V306-A311 HydrophobicContact CG1-CB 3.25Å; V306-A311 WeakPolarHBondContact CG1-O 3.44Å; V306-I313 HydrophobicContact CG1-CD1 4.22Å; V306-I313 HydrophobicContact CG1-CG1 4.34Å; V306-I313 HydrophobicContact CG2-CD1 4.33Å
307D50.1Low78.9Confident144 Ų14452.6 Ų52.677%0.7729%0.294SS*.  trans-84.212-168.4-62.4-38000114.2K305K305-D307 PolarHBondContact O-N 3.01Å
308S54.4Low78.9Confident59 Ų5952.4 Ų52.441%0.41329%0.294SS..SBendtrans-83.1130169.858.30000109.3V306 D310 A311V306-S308 VanDerWaalsContact C-N 3.25Å; V306-S308 PolarHBondContact O-N 2.86Å; S308-D310 PolarHBondContact O-N 3.3Å; S308-A311 PolarHBondContact O-N 2.91Å; S308-A311 WeakPolarHBondContact OG-CB 3.33Å
309P48.2Very low79.1Confident131 Ų13151.4 Ų51.485%0.85129%0.287SS*.THydrogen-bonded Turntrans-53.2-21.7174.3-4.33000113.1
310D47.8Very low79.4Confident133 Ų13349.1 Ų49.171%0.71128%0.276SS*.THydrogen-bonded Turntrans-91.716.8178.4-50.6-41.8000113.8P84 S308P84-D310 WeakPolarHBondContact CG-O 3.41Å; S308-D310 PolarHBondContact O-N 3.3Å
311A54.8Low79.5Confident17 Ų1749.8 Ų49.814%0.1428%0.279CS..  trans-132.164.7-179.900000111.9V306 S308 I313V306-A311 HydrophobicContact CG1-CB 3.25Å; V306-A311 WeakPolarHBondContact CG1-O 3.44Å; S308-A311 PolarHBondContact O-N 2.91Å; S308-A311 WeakPolarHBondContact OG-CB 3.33Å; A311-I313 PolarHBondContact O-N 2.94Å
312S67.3Low79.8Confident73 Ų7348.3 Ų48.351%0.5127%0.271SS..  trans-78.365.9176.768.40000111.9P84 D314P84-S312 WeakPolarHBondContact CB-OG 3.04Å; S312-D314 PolarHBondContact O-N 3.02Å
313I86.7Confident80.1Confident15 Ų1543.1 Ų43.18%0.07724%0.243CC..  trans-72121.4164.7-63.2-178.6000106.7K82 Y87 F188 L301 V306 A311 W315K82-I313 HydrophobicContact CG-CD1 4.4Å; Y87-I313 HydrophobicContact CE1-CG2 3.8Å; Y87-I313 HydrophobicContact CE2-CB 4.31Å; Y87-I313 HydrophobicContact CE2-CG1 3.83Å; Y87-I313 HydrophobicContact CE2-CG2 4.31Å; F188-I313 HydrophobicContact CE1-CD1 4.07Å; F188-I313 HydrophobicContact CZ-CD1 3.9Å; L301-I313 HydrophobicContact CD2-CB 4.48Å; L301-I313 HydrophobicContact CD2-CG2 3.79Å; L301-I313 WeakPolarHBondContact CD2-O 3.45Å; V306-I313 HydrophobicContact CG1-CD1 4.22Å; V306-I313 HydrophobicContact CG1-CG1 4.34Å; V306-I313 HydrophobicContact CG2-CD1 4.33Å; A311-I313 PolarHBondContact O-N 2.94Å; I313-W315 HydrophobicContact CG2-CE3 3.92Å; I313-W315 HydrophobicContact CG2-CH2 4.14Å; I313-W315 HydrophobicContact CG2-CZ3 3.29Å
314D88.1Confident80.5Confident79 Ų7941.6 Ų41.642%0.42224%0.238SC..  trans-148.5145.1-176.2-169.521.5000112.3Y87 S312 K340Y87-D314 WeakPolarHBondContact CD1-O 3.34Å; S312-D314 PolarHBondContact O-N 3.02Å; D314-K340 WeakPolarHBondContact O-CE 3.42Å; D314-K340 PolarHBondContact O-NZ 3.38Å
315W92.9Very high80.9Confident0 Ų046.5 Ų46.50%027%0.265CS..  trans-161.1150.3171.559.779.8000110.7L58 Y87 V296 M297 P298 L300 L301 L304 I313 L318 K340 D342L58-W315 HydrophobicContact CD1-CH2 4.2Å; L58-W315 HydrophobicContact CD2-CH2 4.07Å; Y87-W315 HydrophobicContact CE1-CE3 4.4Å; V296-W315 HydrophobicContact CG1-CZ2 4.43Å; M297-W315 PolarHBondContact O-NE1 2.83Å; P298-W315 WeakPolarHBondContact CB-O 3.49Å; L300-W315 HydrophobicContact CB-CZ2 4.31Å; L300-W315 HydrophobicContact CD2-CZ2 4.22Å; L300-W315 HydrophobicContact CG-CZ2 4.42Å; L301-W315 HydrophobicContact CD1-CD2 4.23Å; L301-W315 HydrophobicContact CD1-CG 4.48Å; L301-W315 HydrophobicContact CD2-CD2 3.89Å; L301-W315 HydrophobicContact CD2-CE3 3.67Å; L301-W315 HydrophobicContact CD2-CH2 3.3Å; L301-W315 HydrophobicContact CD2-CZ2 3.48Å; L301-W315 VanDerWaalsContact CD2-CZ2 3.48Å; L301-W315 HydrophobicContact CD2-CZ3 3.41Å; L301-W315 VanDerWaalsContact CD2-CZ3 3.41Å; L301-W315 HydrophobicContact CG-CD2 4.18Å; L301-W315 HydrophobicContact CG-CE3 4.45Å; L301-W315 HydrophobicContact CG-CH2 4.09Å; L301-W315 HydrophobicContact CG-CZ2 3.74Å; L301-W315 HydrophobicContact CG-CZ3 4.45Å; L304-W315 HydrophobicContact CD1-CH2 3.8Å; I313-W315 HydrophobicContact CG2-CE3 3.92Å; I313-W315 HydrophobicContact CG2-CH2 4.14Å; I313-W315 HydrophobicContact CG2-CZ3 3.29Å; W315-L318 HydrophobicContact CB-CD2 3.65Å; W315-L318 HydrophobicContact CB-CG 4.16Å; W315-L318 HydrophobicContact CD2-CD1 3.81Å; W315-L318 HydrophobicContact CD2-CD2 4.21Å; W315-L318 HydrophobicContact CD2-CG 3.95Å; W315-L318 HydrophobicContact CE3-CD1 4.1Å; W315-L318 HydrophobicContact CG-CD1 4.13Å; W315-L318 HydrophobicContact CG-CD2 3.75Å; W315-L318 HydrophobicContact CG-CG 3.7Å; W315-L318 HydrophobicContact CZ2-CD1 4.35Å; W315-L318 HydrophobicContact CZ3-CD1 4.43Å; W315-K340 HydrophobicContact CB-CG 4.22Å; W315-D342 WeakPolarHBondContact CA-OD1 3.46Å
316G92.9Very high81.8Confident0 Ų039.5 Ų39.50%023%0.234CC..SBendtrans-83.4-45.5168.300000112.4P298 Q341P298-G316 WeakPolarHBondContact CD-O 3.32Å; P298-G316 VanDerWaalsContact CG-O 3.31Å; P298-G316 WeakPolarHBondContact CG-O 3.49Å; G316-Q341 CarbonylContact C-O 3.51Å; G316-Q341 VanDerWaalsContact CA-O 3.23Å; G316-Q341 WeakPolarHBondContact CA-O 3.44Å; G316-Q341 PolarHBondContact N-O 2.89Å
317T94.8Very high83.1Confident0 Ų038.6 Ų38.60%023%0.229CC..EExtended strand (participates in β ladder)trans-156143.3172.2-176.80000110.5W269 Q341W269-T317 HydrophobicContact CE3-CG2 3.7Å; W269-T317 HydrophobicContact CZ3-CG2 3.99Å; T317-Q341 HydrophobicContact CG2-CB 3.86Å; T317-Q341 PolarHBondContact N-O 3.25Å; T317-Q341 PolarHBondContact O-N 3.26Å
318L97.8Very high85Confident0 Ų035.4 Ų35.40%021%0.212CC..EExtended strand (participates in β ladder)trans-112.7110.8171.4-50.4178.7000109.4L58 L95 Q295 V296 W315 I338 W339 K340L58-L318 HydrophobicContact CD2-CD1 4.43Å; L95-L318 HydrophobicContact CD1-CD1 4.22Å; L95-L318 HydrophobicContact CD1-CD2 3.66Å; L95-L318 HydrophobicContact CD2-CD1 4.37Å; Q295-L318 CarbonylContact C-O 3.51Å; Q295-L318 WeakPolarHBondContact CA-O 3.44Å; V296-L318 HydrophobicContact CB-CB 4.03Å; V296-L318 HydrophobicContact CB-CD1 4.34Å; V296-L318 HydrophobicContact CB-CG 4.43Å; V296-L318 HydrophobicContact CG2-CB 4.34Å; V296-L318 PolarHBondContact N-O 3.32Å; V296-L318 PolarHBondContact O-N 2.93Å; V296-L318 VanDerWaalsContact O-N 3.08Å; W315-L318 HydrophobicContact CB-CD2 3.65Å; W315-L318 HydrophobicContact CB-CG 4.16Å; W315-L318 HydrophobicContact CD2-CD1 3.81Å; W315-L318 HydrophobicContact CD2-CD2 4.21Å; W315-L318 HydrophobicContact CD2-CG 3.95Å; W315-L318 HydrophobicContact CE3-CD1 4.1Å; W315-L318 HydrophobicContact CG-CD1 4.13Å; W315-L318 HydrophobicContact CG-CD2 3.75Å; W315-L318 HydrophobicContact CG-CG 3.7Å; W315-L318 HydrophobicContact CZ2-CD1 4.35Å; W315-L318 HydrophobicContact CZ3-CD1 4.43Å; L318-I338 HydrophobicContact CB-CD1 4.1Å; L318-I338 HydrophobicContact CB-CG1 4.32Å; L318-I338 HydrophobicContact CD1-CD1 4.28Å; L318-W339 CarbonylContact C-O 3.58Å; L318-W339 WeakPolarHBondContact CA-O 3.47Å; L318-K340 HydrophobicContact CD2-CB 3.73Å; L318-K340 HydrophobicContact CD2-CD 4.33Å; L318-K340 HydrophobicContact CD2-CG 3.7Å
319A97.9Very high86.4Confident0 Ų036 Ų360%021%0.209CC..EExtended strand (participates in β ladder)trans-93.9122.4176.300000110.6P267 W269 F292 Y321 I338 W339P267-A319 HydrophobicContact CB-CB 4.2Å; P267-A319 HydrophobicContact CG-CB 3.83Å; W269-A319 HydrophobicContact CH2-CB 3.72Å; W269-A319 HydrophobicContact CZ3-CB 4.14Å; F292-A319 HydrophobicContact CD2-CB 4.31Å; F292-A319 HydrophobicContact CE2-CB 4.08Å; A319-Y321 HydrophobicContact CB-CE2 3.7Å; A319-Y321 WeakPolarHBondContact O-CD2 3.35Å; A319-I338 WeakPolarHBondContact O-CA 3.36Å; A319-W339 HydrophobicContact CB-CB 4.39Å; A319-W339 PolarHBondContact N-O 3.35Å; A319-W339 PolarHBondContact O-N 2.97Å
320V98.5Very high88.4Confident0 Ų031.4 Ų31.40%018%0.184CC..EExtended strand (participates in β ladder)trans-98.9132.1179.11780000110I76 V78 V97 E293 F294 T322 I338I76-V320 HydrophobicContact CG2-CG1 4.18Å; V78-V320 HydrophobicContact CG2-CG2 4.46Å; V97-V320 HydrophobicContact CG1-CG1 3.84Å; V97-V320 HydrophobicContact CG2-CG2 4.35Å; E293-V320 PolarHBondContact N-O 3.02Å; F294-V320 HydrophobicContact CD1-CB 4.48Å; F294-V320 HydrophobicContact CD2-CB 4.12Å; F294-V320 HydrophobicContact CD2-CG2 4.05Å; F294-V320 HydrophobicContact CE1-CB 4.24Å; F294-V320 HydrophobicContact CE1-CG1 4.11Å; F294-V320 HydrophobicContact CE2-CB 3.88Å; F294-V320 HydrophobicContact CE2-CG1 4.46Å; F294-V320 HydrophobicContact CE2-CG2 3.47Å; F294-V320 VanDerWaalsContact CE2-CG2 3.47Å; F294-V320 HydrophobicContact CG-CB 4.43Å; F294-V320 HydrophobicContact CZ-CB 3.93Å; F294-V320 HydrophobicContact CZ-CG1 4.01Å; F294-V320 HydrophobicContact CZ-CG2 3.77Å; F294-V320 PolarHBondContact O-N 2.84Å; V320-T322 HydrophobicContact CG1-CG2 4.3Å; V320-I338 HydrophobicContact CG2-CD1 4.09Å; V320-I338 HydrophobicContact CG2-CG1 4.23Å
321Y97.9Very high90.4Very high14 Ų1427.1 Ų27.16%0.05516%0.162CC..EExtended strand (participates in β ladder)trans-121.2128.7180-62.8-98.4000110.3P276 I281 I291 F292 A319 F337 W339P276-Y321 VanDerWaalsContact CG-OH 3.31Å; P276-Y321 WeakPolarHBondContact CG-OH 3.38Å; I281-Y321 HydrophobicContact CD1-CD1 3.62Å; I281-Y321 HydrophobicContact CD1-CE1 3.33Å; I281-Y321 HydrophobicContact CD1-CE2 4.47Å; I281-Y321 HydrophobicContact CD1-CG 4.32Å; I281-Y321 HydrophobicContact CG1-CD1 4.41Å; I281-Y321 HydrophobicContact CG1-CE1 4.34Å; I281-Y321 HydrophobicContact CG2-CD1 4.39Å; I281-Y321 HydrophobicContact CG2-CG 4.35Å; I291-Y321 CarbonylContact O-C 3.47Å; I291-Y321 WeakPolarHBondContact O-CA 3.49Å; F292-Y321 HydrophobicContact CB-CD1 4.14Å; F292-Y321 HydrophobicContact CB-CE1 3.9Å; A319-Y321 HydrophobicContact CB-CE2 3.7Å; A319-Y321 WeakPolarHBondContact O-CD2 3.35Å; Y321-F337 AromaticContact CD2-CD1 3.82Å; Y321-F337 HydrophobicContact CD2-CD1 3.82Å; Y321-F337 HydrophobicContact CD2-CE1 4.4Å; Y321-F337 HydrophobicContact CG-CD1 4.26Å; Y321-F337 PolarHBondContact N-O 3.33Å; Y321-F337 PolarHBondContact O-N 3.14Å; Y321-F337 VanDerWaalsContact O-N 3.09Å; Y321-W339 HydrophobicContact CE2-CB 3.96Å
322T97.8Very high92.2Very high0 Ų032.1 Ų32.10%018%0.18CC..EExtended strand (participates in β ladder)trans-122.6164.3-179.580.20000112.4R74 I76 R290 I291 E293 V320 A324 E336R74-T322 PolarHBondContact NH2-OG1 3.34Å; I76-T322 HydrophobicContact CD1-CG2 3.7Å; I76-T322 HydrophobicContact CG1-CG2 4.24Å; R290-T322 CarbonylContact C-O 3.55Å; R290-T322 WeakPolarHBondContact CA-O 3.24Å; R290-T322 WeakPolarHBondContact CB-O 3.4Å; I291-T322 PolarHBondContact N-O 3.49Å; I291-T322 PolarHBondContact O-N 3.48Å; E293-T322 HydrophobicContact CB-CG2 3.92Å; E293-T322 HydrophobicContact CG-CG2 4.14Å; E293-T322 PolarHBondContact OE2-OG1 2.83Å; V320-T322 HydrophobicContact CG1-CG2 4.3Å; T322-A324 PolarHBondContact O-N 3.19Å; T322-E336 WeakPolarHBondContact CA-OE2 3.37Å; T322-E336 HydrophobicContact CG2-CB 4.47Å; T322-E336 HydrophobicContact CG2-CG 4.15Å
323C96.9Very high93.6Very high0 Ų029.3 Ų29.30%016%0.158CC..EExtended strand (participates in β ladder)trans-53.4124.9176.7-176.30000112.8C284 D325 S326 C327 E336C284-C323 HydrophobicContact CB-CB 4.05Å; C323-D325 PolarHBondContact O-N 3.34Å; C323-S326 PolarHBondContact O-N 3.2Å; C323-C327 PolarHBondContact SG-N 3.24Å; C323-E336 PolarHBondContact N-OE1 3.06Å; C323-E336 PolarHBondContact N-OE2 3.14Å
324A95.5Very high94Very high21 Ų2129 Ų2917%0.17416%0.157CC..THydrogen-bonded Turntrans-57-47.7178.200000112.5R263 R289 I291 T322 S326R263-A324 PolarHBondContact NH2-O 3.12Å; R289-A324 HydrophobicContact CG-CB 4.03Å; R289-A324 WeakPolarHBondContact O-CB 3.32Å; R289-A324 PolarHBondContact O-N 2.98Å; I291-A324 HydrophobicContact CD1-CB 4.34Å; I291-A324 HydrophobicContact CG1-CB 4.31Å; I291-A324 HydrophobicContact CG2-CB 3.89Å; T322-A324 PolarHBondContact O-N 3.19Å; A324-S326 PolarHBondContact O-N 2.54Å
325D94.8Very high94.5Very high108 Ų10828.5 Ų28.558%0.57816%0.16SC*.THydrogen-bonded Turntrans-76.1-1.2-179.7-61.8-19.9000113.7Q68 S288 C323 C327Q68-D325 PolarHBondContact NE2-O 3.09Å; S288-D325 WeakPolarHBondContact CB-OD2 3.27Å; S288-D325 PolarHBondContact OG-OD2 3.24Å; C323-D325 PolarHBondContact O-N 3.34Å; D325-C327 VanDerWaalsContact C-N 3.28Å; D325-C327 PolarHBondContact O-N 3.07Å
326S94.9Very high94.7Very high0 Ų029 Ų290%016%0.162CC..  trans40.953.2-167.5-145.30000113.9Q68 R74 R99 Q101 C323 A324Q68-S326 VanDerWaalsContact OE1-CB 3.32Å; R74-S326 PolarHBondContact NE-OG 2.95Å; R99-S326 PolarHBondContact NH1-O 3.48Å; R99-S326 PolarHBondContact NH1-OG 2.89Å; Q101-S326 VanDerWaalsContact CD-OG 3.32Å; Q101-S326 PolarHBondContact NE2-O 2.87Å; Q101-S326 PolarHBondContact OE1-OG 3.16Å; C323-S326 PolarHBondContact O-N 3.2Å; A324-S326 PolarHBondContact O-N 2.54Å
327C94.1Very high94.9Very high16 Ų1631 Ų3111%0.10817%0.171CC..  trans-49.6142.8-170.6700000114.9R99 Q101 C286 C323 D325R99-C327 VanDerWaalsContact NH1-N 3.19Å; R99-C327 PolarHBondContact NH1-O 3.23Å; R99-C327 PolarHBondContact NH2-O 3.44Å; R99-C327 PolarHBondContact NH2-SG 3.1Å; Q101-C327 PolarHBondContact NE2-O 3.05Å; Q101-C327 VanDerWaalsContact NE2-O 3.11Å; C286-C327 HydrophobicContact CB-CB 3.73Å; C286-C327 WeakPolarHBondContact SG-CB 3.24Å; C286-C327 VanDerWaalsContact SG-SG 3.63Å; C323-C327 PolarHBondContact SG-N 3.24Å; D325-C327 VanDerWaalsContact C-N 3.28Å; D325-C327 PolarHBondContact O-N 3.07Å
328D90.3Very high95.1Very high78 Ų7831.4 Ų31.442%0.41717%0.173SC..  trans-79.2126.4177.3-170.6-0000110.3R70 G330R70-D328 WeakPolarHBondContact CD-OD2 3.5Å; R70-D328 HydrophobicContact CG-CB 4.49Å; R70-D328 IonicContact CZ-OD2 3Å; R70-D328 IonicContact NE-OD2 2.82Å; R70-D328 PolarHBondContact NE-OD2 2.81Å; R70-D328 VanDerWaalsContact NE-OD2 3.09Å; D328-G330 PolarHBondContact OD1-N 3.34Å
329Q83.9Confident95Very high72 Ų7233.3 Ų33.334%0.33618%0.181SC..  trans-123.218.9175.8-62.6-64.4-44.300110.9K332 S334Q329-K332 HydrophobicContact CB-CB 4.37Å; Q329-K332 WeakPolarHBondContact O-CB 3.42Å; Q329-K332 PolarHBondContact O-N 3.25Å; Q329-S334 VanDerWaalsContact CG-OG 3.32Å; Q329-S334 WeakPolarHBondContact CG-OG 3.28Å
330G89.9Confident94.9Very high33 Ų3333.4 Ų33.434%0.3418%0.181SC..THydrogen-bonded Turntrans64.8-134.8-169.300000111D328 K332D328-G330 PolarHBondContact OD1-N 3.34Å; G330-K332 VanDerWaalsContact C-N 3.26Å; G330-K332 PolarHBondContact O-N 3.21Å
331N90.1Very high94.8Very high44 Ų4433.4 Ų33.424%0.23518%0.181CC..THydrogen-bonded Turntrans-84.83.5-178.1-68-18.8000113.5S36 L38 F108S36-N331 WeakPolarHBondContact CB-O 3.35Å; S36-N331 WeakPolarHBondContact OG-CB 3.21Å; S36-N331 PolarHBondContact OG-O 3.32Å; L38-N331 HydrophobicContact CB-CB 4.37Å; F108-N331 HydrophobicContact CZ-CB 4.49Å
332K93.3Very high94.5Very high121 Ų12133.5 Ų33.553%0.52618%0.182SC..SBendtrans-79.5154.6-176.5-63.4-176.7179-178.10112.4D39 Q329 G330D39-K332 HydrophobicContact CB-CB 4.42Å; D39-K332 HydrophobicContact CB-CG 3.87Å; D39-K332 WeakPolarHBondContact OD2-CG 3.37Å; Q329-K332 HydrophobicContact CB-CB 4.37Å; Q329-K332 WeakPolarHBondContact O-CB 3.42Å; Q329-K332 PolarHBondContact O-N 3.25Å; G330-K332 VanDerWaalsContact C-N 3.26Å; G330-K332 PolarHBondContact O-N 3.21Å
333Y95.9Very high93.9Very high15 Ų1536.9 Ų36.96%0.05920%0.197CC..PPolyproline II helixtrans-86.7120.9171.4-73.5-108.6000109.7W34 L35 S36 D39 I40 P41 F77 F98 R99 S100W34-Y333 HydrophobicContact CE3-CD1 4.35Å; W34-Y333 AromaticContact CE3-CE1 3.42Å; W34-Y333 HydrophobicContact CE3-CE1 3.42Å; W34-Y333 VanDerWaalsContact CE3-CE1 3.42Å; W34-Y333 AromaticContact CE3-CZ 3.58Å; W34-Y333 HydrophobicContact CZ3-CD1 4.09Å; W34-Y333 AromaticContact CZ3-CE1 3.59Å; W34-Y333 HydrophobicContact CZ3-CE1 3.59Å; L35-Y333 PolarHBondContact N-OH 2.74Å; L35-Y333 VanDerWaalsContact N-OH 3.11Å; S36-Y333 PolarHBondContact N-OH 3.27Å; S36-Y333 VanDerWaalsContact N-OH 3.14Å; S36-Y333 PolarHBondContact O-OH 2.92Å; D39-Y333 WeakPolarHBondContact O-CD2 3.24Å; I40-Y333 HydrophobicContact CG1-CE2 4.22Å; P41-Y333 VanDerWaalsContact CD-CG 3.48Å; P41-Y333 HydrophobicContact CG-CD1 4.13Å; P41-Y333 HydrophobicContact CG-CD2 4.39Å; P41-Y333 HydrophobicContact CG-CG 3.78Å; F77-Y333 HydrophobicContact CD2-CD1 4.29Å; F77-Y333 AromaticContact CD2-CE1 3.93Å; F77-Y333 HydrophobicContact CD2-CE1 3.93Å; F77-Y333 HydrophobicContact CE2-CD1 4.35Å; F77-Y333 AromaticContact CE2-CE1 3.61Å; F77-Y333 HydrophobicContact CE2-CE1 3.61Å; F77-Y333 HydrophobicContact CZ-CE1 4.14Å; F98-Y333 HydrophobicContact CB-CD1 4.18Å; R99-Y333 WeakPolarHBondContact O-CA 3.42Å; S100-Y333 VanDerWaalsContact CB-CE1 3.46Å
334S96.4Very high93Very high8 Ų838.8 Ų38.86%0.05621%0.209CC..EExtended strand (participates in β ladder)trans-85.1128.1177-53.70000109.7F98 R99 Q329 E336F98-S334 CarbonylContact C-O 3.26Å; F98-S334 VanDerWaalsContact CA-O 3.27Å; F98-S334 WeakPolarHBondContact CA-O 3.3Å; R99-S334 PolarHBondContact N-O 3.3Å; R99-S334 PolarHBondContact NH2-OG 3.07Å; R99-S334 PolarHBondContact O-N 2.67Å; Q329-S334 VanDerWaalsContact CG-OG 3.32Å; Q329-S334 WeakPolarHBondContact CG-OG 3.28Å; S334-E336 PolarHBondContact O-N 3.33Å
335S97.1Very high91.4Very high69 Ų6945 Ų4548%0.48324%0.235SC..EExtended strand (participates in β ladder)trans-69.4124.6171-179.20000110.4R290R290-S335 PolarHBondContact NH2-O 3.47Å
336E97.8Very high89.1Confident9 Ų948.2 Ų48.24%0.04225%0.246CC..EExtended strand (participates in β ladder)trans-110176.1176.7-62.8-62.4-173.700110.9V97 R99 R290 T322 C323 S334V97-E336 HydrophobicContact CB-CB 4.24Å; V97-E336 HydrophobicContact CG1-CB 3.86Å; V97-E336 PolarHBondContact O-N 2.89Å; R99-E336 HydrophobicContact CB-CG 3.63Å; R99-E336 WeakPolarHBondContact CD-OE1 3.13Å; R99-E336 IonicContact CZ-OE1 2.69Å; R99-E336 IonicContact NE-OE1 3.81Å; R99-E336 PolarHBondContact NE-OE1 2.65Å; R99-E336 IonicContact NH2-OE1 3.89Å; R290-E336 IonicContact CZ-OE2 3.61Å; R290-E336 IonicContact NE-OE2 2.89Å; R290-E336 PolarHBondContact NE-OE2 3.26Å; T322-E336 WeakPolarHBondContact CA-OE2 3.37Å; T322-E336 HydrophobicContact CG2-CB 4.47Å; T322-E336 HydrophobicContact CG2-CG 4.15Å; C323-E336 PolarHBondContact N-OE1 3.06Å; C323-E336 PolarHBondContact N-OE2 3.14Å; S334-E336 PolarHBondContact O-N 3.33Å
337F97.7Very high86.2Confident43 Ų4361.3 Ų61.319%0.18930%0.303CS..EExtended strand (participates in β ladder)trans-108142.3-170.3-175.4-107000111.5I281 P282 Y321 W339I281-F337 HydrophobicContact CG1-CD1 4.49Å; I281-F337 HydrophobicContact CG1-CE1 4.21Å; I281-F337 HydrophobicContact CG2-CD1 3.97Å; I281-F337 HydrophobicContact CG2-CE1 4.4Å; P282-F337 HydrophobicContact CG-CD2 3.58Å; P282-F337 HydrophobicContact CG-CE2 3.87Å; P282-F337 HydrophobicContact CG-CG 4.08Å; Y321-F337 AromaticContact CD2-CD1 3.82Å; Y321-F337 HydrophobicContact CD2-CD1 3.82Å; Y321-F337 HydrophobicContact CD2-CE1 4.4Å; Y321-F337 HydrophobicContact CG-CD1 4.26Å; Y321-F337 PolarHBondContact N-O 3.33Å; Y321-F337 PolarHBondContact O-N 3.14Å; Y321-F337 VanDerWaalsContact O-N 3.09Å; F337-W339 HydrophobicContact CE1-CB 4.28Å; F337-W339 AromaticContact CE1-CE3 3.76Å; F337-W339 HydrophobicContact CE1-CE3 3.76Å; F337-W339 AromaticContact CZ-CE3 3.68Å; F337-W339 HydrophobicContact CZ-CE3 3.68Å; F337-W339 HydrophobicContact CZ-CZ3 4.19Å
338I97.9Very high85.8Confident9 Ų963.6 Ų63.65%0.04631%0.313CS..EExtended strand (participates in β ladder)trans-132137.2176.5-172.6161.9000109.3V78 S92 L95 V97 L318 A319 V320V78-I338 HydrophobicContact CG1-CD1 3.95Å; S92-I338 WeakPolarHBondContact CB-O 3.42Å; S92-I338 PolarHBondContact OG-O 2.88Å; L95-I338 HydrophobicContact CB-CD1 4.17Å; L95-I338 HydrophobicContact CB-CG2 3.73Å; L95-I338 HydrophobicContact CD1-CD1 3.94Å; L95-I338 HydrophobicContact CD1-CG1 4.21Å; L95-I338 HydrophobicContact CD1-CG2 4.45Å; V97-I338 HydrophobicContact CG2-CB 3.61Å; V97-I338 HydrophobicContact CG2-CD1 3.74Å; V97-I338 HydrophobicContact CG2-CG1 4.23Å; V97-I338 HydrophobicContact CG2-CG2 3.94Å; L318-I338 HydrophobicContact CB-CD1 4.1Å; L318-I338 HydrophobicContact CB-CG1 4.32Å; L318-I338 HydrophobicContact CD1-CD1 4.28Å; A319-I338 WeakPolarHBondContact O-CA 3.36Å; V320-I338 HydrophobicContact CG2-CD1 4.09Å; V320-I338 HydrophobicContact CG2-CG1 4.23Å
339W97.3Very high85.6Confident39 Ų3962.8 Ų62.815%0.14831%0.307CS..EExtended strand (participates in β ladder)trans-119.4118.9178.5-171.7-86.3000109.6W269 H274 P276 L318 A319 Y321 F337W269-W339 AromaticContact CH2-CD1 3.78Å; W269-W339 HydrophobicContact CH2-CG 4.47Å; W269-W339 AromaticContact CZ3-CD1 3.78Å; H274-W339 AromaticContact CD2-CE2 3.66Å; H274-W339 AromaticContact CD2-CZ2 3.67Å; H274-W339 AromaticContact CD2-NE1 3.36Å; H274-W339 PolarHBondContact CD2-NE1 3.46Å; H274-W339 AromaticContact CE1-CE2 3.95Å; H274-W339 AromaticContact CE1-CH2 3.83Å; H274-W339 AromaticContact CE1-CZ2 3.32Å; H274-W339 WeakPolarHBondContact CE1-CZ2 3.1Å; H274-W339 AromaticContact CG-CZ2 3.96Å; H274-W339 AromaticContact ND1-CZ2 3.76Å; H274-W339 AromaticContact NE2-CE2 3.37Å; H274-W339 AromaticContact NE2-CZ2 3.24Å; H274-W339 WeakPolarHBondContact NE2-CZ2 3.28Å; H274-W339 AromaticContact NE2-NE1 3.53Å; H274-W339 WeakPolarHBondContact O-CZ2 3.21Å; H274-W339 PolarHBondContact O-NE1 3.02Å; P276-W339 HydrophobicContact CB-CD2 3.86Å; P276-W339 HydrophobicContact CB-CE3 4Å; P276-W339 HydrophobicContact CB-CG 4.43Å; P276-W339 HydrophobicContact CB-CH2 4.11Å; P276-W339 HydrophobicContact CB-CZ2 3.97Å; P276-W339 HydrophobicContact CB-CZ3 4.13Å; P276-W339 HydrophobicContact CG-CD2 4.07Å; P276-W339 HydrophobicContact CG-CG 4.13Å; L318-W339 CarbonylContact C-O 3.58Å; L318-W339 WeakPolarHBondContact CA-O 3.47Å; A319-W339 HydrophobicContact CB-CB 4.39Å; A319-W339 PolarHBondContact N-O 3.35Å; A319-W339 PolarHBondContact O-N 2.97Å; Y321-W339 HydrophobicContact CE2-CB 3.96Å; F337-W339 HydrophobicContact CE1-CB 4.28Å; F337-W339 AromaticContact CE1-CE3 3.76Å; F337-W339 HydrophobicContact CE1-CE3 3.76Å; F337-W339 AromaticContact CZ-CE3 3.68Å; F337-W339 HydrophobicContact CZ-CE3 3.68Å; F337-W339 HydrophobicContact CZ-CZ3 4.19Å
340K95.8Very high85.7Confident2 Ų262.3 Ų62.31%0.00931%0.305CS..EExtended strand (participates in β ladder)trans-96.2125.8176178.1177.8-172.8-95.30109.9D91 S92 L95 H274 D314 W315 L318 D342D91-K340 WeakPolarHBondContact O-CD 2.98Å; S92-K340 WeakPolarHBondContact OG-CB 2.9Å; S92-K340 PolarHBondContact OG-N 3.14Å; L95-K340 HydrophobicContact CD1-CB 4.12Å; L95-K340 HydrophobicContact CD1-CD 4.34Å; H274-K340 PolarHBondContact CD2-O 2.94Å; H274-K340 PolarHBondContact NE2-O 2.85Å; D314-K340 WeakPolarHBondContact O-CE 3.42Å; D314-K340 PolarHBondContact O-NZ 3.38Å; W315-K340 HydrophobicContact CB-CG 4.22Å; L318-K340 HydrophobicContact CD2-CB 3.73Å; L318-K340 HydrophobicContact CD2-CD 4.33Å; L318-K340 HydrophobicContact CD2-CG 3.7Å; K340-D342 VanDerWaalsContact CE-OD1 3.27Å; K340-D342 WeakPolarHBondContact CE-OD1 3.49Å; K340-D342 IonicContact NZ-OD1 2.66Å; K340-D342 PolarHBondContact NZ-OD1 3.06Å; K340-D342 IonicContact NZ-OD2 3.2Å; K340-D342 PolarHBondContact NZ-OD2 2.75Å
341Q94.6Very high85.4Confident1 Ų164 Ų641%0.00530%0.303CS..EExtended strand (participates in β ladder)trans-116.1132.5165.9-176-173.759.900108.7N90 W269 V270 S271 E273 G316 T317N90-Q341 WeakPolarHBondContact OD1-CA 3.45Å; W269-Q341 HydrophobicContact CE3-CB 4.24Å; W269-Q341 HydrophobicContact CZ3-CB 4.25Å; V270-Q341 HydrophobicContact CG2-CG 3.96Å; S271-Q341 PolarHBondContact O-NE2 2.77Å; E273-Q341 PolarHBondContact O-NE2 3.17Å; G316-Q341 CarbonylContact C-O 3.51Å; G316-Q341 VanDerWaalsContact CA-O 3.23Å; G316-Q341 WeakPolarHBondContact CA-O 3.44Å; G316-Q341 PolarHBondContact N-O 2.89Å; T317-Q341 HydrophobicContact CG2-CB 3.86Å; T317-Q341 PolarHBondContact N-O 3.25Å; T317-Q341 PolarHBondContact O-N 3.26Å
342D92Very high85.1Confident15 Ų1565.3 Ų65.38%0.0831%0.308CS..PPolyproline II helixtrans-96.1159.9174.2-65.4-52.2000111.7R89 N90 W315 K340R89-D342 VanDerWaalsContact CA-OD2 3.25Å; R89-D342 WeakPolarHBondContact CA-OD2 3.21Å; R89-D342 HydrophobicContact CG-CB 4.4Å; N90-D342 PolarHBondContact N-OD2 3.43Å; N90-D342 PolarHBondContact OD1-N 2.96Å; W315-D342 WeakPolarHBondContact CA-OD1 3.46Å; K340-D342 VanDerWaalsContact CE-OD1 3.27Å; K340-D342 WeakPolarHBondContact CE-OD1 3.49Å; K340-D342 IonicContact NZ-OD1 2.66Å; K340-D342 PolarHBondContact NZ-OD1 3.06Å; K340-D342 IonicContact NZ-OD2 3.2Å; K340-D342 PolarHBondContact NZ-OD2 2.75Å
343F85.8Confident84.6Confident71 Ų7161.5 Ų61.531%0.31129%0.293SS..PPolyproline II helixtrans-61.2148.6167.9-63.5-70.9000110.4F244 V270 P298 E345F244-F343 HydrophobicContact CD2-CD1 4.38Å; F244-F343 AromaticContact CE2-CD1 3.71Å; F244-F343 HydrophobicContact CE2-CD1 3.71Å; F244-F343 AromaticContact CE2-CE1 3.71Å; F244-F343 HydrophobicContact CE2-CE1 3.71Å; V270-F343 HydrophobicContact CB-CD1 3.89Å; V270-F343 HydrophobicContact CB-CE1 3.88Å; V270-F343 HydrophobicContact CG1-CD1 4.1Å; V270-F343 HydrophobicContact CG1-CE1 3.57Å; V270-F343 HydrophobicContact CG1-CZ 4.29Å; V270-F343 HydrophobicContact CG2-CD1 4.09Å; V270-F343 HydrophobicContact CG2-CE1 4.36Å; P298-F343 HydrophobicContact CB-CE2 4.09Å; P298-F343 HydrophobicContact CB-CZ 3.96Å; P298-F343 HydrophobicContact CG-CZ 3.87Å; F343-E345 PolarHBondContact O-N 3.44Å
344T77.5Confident83.8Confident40 Ų4064.9 Ų64.925%0.24531%0.31CS..PPolyproline II helixtrans-70.8127.3170.537.60000109D240 S271 Q346D240-T344 WeakPolarHBondContact OD2-CB 3.36Å; D240-T344 WeakPolarHBondContact OD2-CG2 3.39Å; D240-T344 PolarHBondContact OD2-OG1 3.16Å; S271-T344 WeakPolarHBondContact OG-CG2 3.28Å; T344-Q346 PolarHBondContact O-N 2.93Å; T344-Q346 VanDerWaalsContact O-N 3.15Å
345E62.9Low82.8Confident153 Ų15369.2 Ų69.272%0.71533%0.329SS*.PPolyproline II helixtrans-62.3117.7169.5-70.9175.6178.700107.4F343 K347F343-E345 PolarHBondContact O-N 3.44Å; E345-K347 PolarHBondContact O-N 2.98Å; E345-K347 VanDerWaalsContact O-N 3.08Å
346Q45.7Very low81.6Confident175 Ų17569.3 Ų69.382%0.81832%0.317SS*.  trans-59.4113.9165.1-70.8178.4-1300106.4T344T344-Q346 PolarHBondContact O-N 2.93Å; T344-Q346 VanDerWaalsContact O-N 3.15Å
347K34.2Very low80.1Confident274 Ų27474.7 Ų74.7100%1.19134%0.342SS*.  trans-74.40178.6-90.3-174.2176.4176.70112.1E345E345-K347 PolarHBondContact O-N 2.98Å; E345-K347 VanDerWaalsContact O-N 3.08Å

Retrieved 347 of 347 residues in 491.7 ms (Link to these results)