A0A060YSI4_ONCMY Loading...

Gamma-glutamylcyclotransferase

Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides.

AlphaFold DB , UniProt , Accession A0A060YSI4, Species ONCMY (Oncorhynchus mykiss, Rainbow trout), Gene chac1, Length 200 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M49.5Very low52Low148 Ų14894.5 Ų94.573%0.72953%0.525SS*.  0142.40-169.6172.1-70.600107.8D5 I6 T106M1-D5 HydrophobicContact CG-CB 3.69Å; M1-D5 HydrophobicContact SD-CB 4.17Å; M1-I6 HydrophobicContact CB-CG1 4.38Å; M1-I6 HydrophobicContact CG-CG1 4Å; M1-I6 HydrophobicContact SD-CG1 3.69Å; M1-T106 PolarHBondContact O-OG1 3.15Å
2K53.8Low51.8Low157 Ų15794.9 Ų94.968%0.68354%0.539SS*.  trans-76.4144.9176.1-63176179.5175.20108.1K4 D5 I6K2-K4 PolarHBondContact O-N 2.69Å; K2-K4 VanDerWaalsContact O-N 3.08Å; K2-D5 WeakPolarHBondContact CB-OD2 3.32Å; K2-D5 PolarHBondContact N-OD2 3.21Å; K2-D5 VanDerWaalsContact N-OD2 3.15Å; K2-D5 WeakPolarHBondContact O-CB 3.47Å; K2-D5 PolarHBondContact O-N 3.41Å; K2-I6 PolarHBondContact O-N 3.03Å
3P54.7Low52.4Low12 Ų1291.4 Ų91.48%0.07852%0.517CS..Hα-helixtrans-58.5-28.6-177.39.5-21.1000113.4D5 I6 I7 L91 N95 T106 L125 Y127P3-D5 VanDerWaalsContact C-N 3.27Å; P3-D5 PolarHBondContact O-N 3.14Å; P3-I6 PolarHBondContact O-N 2.84Å; P3-I7 WeakPolarHBondContact O-CD1 3.42Å; P3-I7 WeakPolarHBondContact O-CG1 3.49Å; P3-I7 PolarHBondContact O-N 3.15Å; P3-L91 HydrophobicContact CB-CD2 4.28Å; P3-N95 WeakPolarHBondContact CG-OD1 3.46Å; P3-T106 HydrophobicContact CB-CG2 4Å; P3-T106 HydrophobicContact CG-CG2 3.79Å; P3-L125 HydrophobicContact CB-CD2 4.38Å; P3-Y127 HydrophobicContact CG-CE1 4.42Å
4K53.6Low53.7Low158 Ų15892.5 Ų92.569%0.68753%0.527SS*.Hα-helixtrans-61.3-32.9172.8-68.5-172175.9-174.30113.3K2 I7 A8K2-K4 PolarHBondContact O-N 2.69Å; K2-K4 VanDerWaalsContact O-N 3.08Å; K4-I7 PolarHBondContact O-N 3.03Å; K4-A8 VanDerWaalsContact O-CB 3.3Å; K4-A8 WeakPolarHBondContact O-CB 3.36Å; K4-A8 PolarHBondContact O-N 3.2Å
5D55.8Low55.7Low88 Ų8888.7 Ų88.747%0.47151%0.508SS..Hα-helixtrans-76.7-32.1-179.2-46-34.6000111M1 K2 P3 I7M1-D5 HydrophobicContact CG-CB 3.69Å; M1-D5 HydrophobicContact SD-CB 4.17Å; K2-D5 WeakPolarHBondContact CB-OD2 3.32Å; K2-D5 PolarHBondContact N-OD2 3.21Å; K2-D5 VanDerWaalsContact N-OD2 3.15Å; K2-D5 WeakPolarHBondContact O-CB 3.47Å; K2-D5 PolarHBondContact O-N 3.41Å; P3-D5 VanDerWaalsContact C-N 3.27Å; P3-D5 PolarHBondContact O-N 3.14Å; D5-I7 PolarHBondContact O-N 3.05Å
6I57.2Low57.8Low27 Ų2783.8 Ų83.814%0.13848%0.48CS..Hα-helixtrans-64-33.2173.2-63.2177.9000110.6M1 K2 P3 T106 L108 L125M1-I6 HydrophobicContact CB-CG1 4.38Å; M1-I6 HydrophobicContact CG-CG1 4Å; M1-I6 HydrophobicContact SD-CG1 3.69Å; K2-I6 PolarHBondContact O-N 3.03Å; P3-I6 PolarHBondContact O-N 2.84Å; I6-T106 WeakPolarHBondContact CD1-OG1 3.47Å; I6-L108 HydrophobicContact CG2-CD1 3.58Å; I6-L108 HydrophobicContact CG2-CD2 4.19Å; I6-L108 HydrophobicContact CG2-CG 3.76Å; I6-L125 HydrophobicContact CD1-CD1 3.98Å
7I56.6Low59.9Low41 Ų4180.7 Ų80.721%0.2146%0.459CS..Hα-helixtrans-87.8-36.1-177.3-59.5161.3000111.1P3 K4 D5 G9 K10 L13 L91P3-I7 WeakPolarHBondContact O-CD1 3.42Å; P3-I7 WeakPolarHBondContact O-CG1 3.49Å; P3-I7 PolarHBondContact O-N 3.15Å; K4-I7 PolarHBondContact O-N 3.03Å; D5-I7 PolarHBondContact O-N 3.05Å; I7-G9 PolarHBondContact O-N 3.02Å; I7-K10 CarbonylContact O-C 3.49Å; I7-K10 PolarHBondContact O-N 3.23Å; I7-L13 HydrophobicContact CB-CD1 4.34Å; I7-L13 HydrophobicContact CG1-CD1 3.83Å; I7-L13 HydrophobicContact CG2-CD1 4.06Å; I7-L91 HydrophobicContact CD1-CD1 3.07Å; I7-L91 HydrophobicContact CD1-CD2 4.15Å; I7-L91 HydrophobicContact CD1-CG 4.21Å; I7-L91 HydrophobicContact CG1-CD1 4.41Å
8A50.8Low61.8Low86 Ų8676.2 Ų76.271%0.71143%0.433SS*.Hα-helixtrans-62.2-25.7179.800000113.4K4K4-A8 VanDerWaalsContact O-CB 3.3Å; K4-A8 WeakPolarHBondContact O-CB 3.36Å; K4-A8 PolarHBondContact O-N 3.2Å
9G48.3Very low63.7Low68 Ų6872.3 Ų72.370%0.70141%0.411SS*.THydrogen-bonded Turntrans-80.2-11.4174.900000115.2I7I7-G9 PolarHBondContact O-N 3.02Å
10K50.3Low65.3Low111 Ų11168.8 Ų68.848%0.48339%0.391SS..SBendtrans-126.597.4-179.1-71.7-176.4179178.40109.3I7 S12I7-K10 CarbonylContact O-C 3.49Å; I7-K10 PolarHBondContact O-N 3.23Å; K10-S12 PolarHBondContact O-N 2.57Å; K10-S12 VanDerWaalsContact O-N 3.14Å
11T41.4Very low66.8Low144 Ų14466.3 Ų66.388%0.88338%0.376SS*.SBendtrans-37.5114.6175.3-41.60000111.7
12S49.7Very low68.9Low99 Ų9959.6 Ų59.669%0.69234%0.344SS*.  trans43.881.3173.5177.20000115K10 T14K10-S12 PolarHBondContact O-N 2.57Å; K10-S12 VanDerWaalsContact O-N 3.14Å; S12-T14 PolarHBondContact O-N 3.16Å
13L58.9Low70.8Confident49 Ų4953.1 Ų53.126%0.25732%0.319SS..  trans-59.3101.3164.9-73.4169.4000109.7I7 S15 L16I7-L13 HydrophobicContact CB-CD1 4.34Å; I7-L13 HydrophobicContact CG1-CD1 3.83Å; I7-L13 HydrophobicContact CG2-CD1 4.06Å; L13-S15 PolarHBondContact O-N 2.9Å; L13-L16 HydrophobicContact CD1-CB 4.48Å; L13-L16 HydrophobicContact CD1-CD1 4.26Å
14T71.8Confident72.7Confident107 Ų10753.6 Ų53.666%0.65632%0.32SS*.SBendtrans-68.9-24.5171.850.10000111.4S12 T83 G84S12-T14 PolarHBondContact O-N 3.16Å; T14-T83 VanDerWaalsContact O-CA 3.3Å; T14-T83 WeakPolarHBondContact O-CA 3.18Å; T14-T83 WeakPolarHBondContact O-CB 3.36Å; T14-G84 PolarHBondContact O-N 3.07Å; T14-G84 VanDerWaalsContact O-N 3.1Å
15S83.2Confident74.7Confident35 Ų3547 Ų4725%0.24529%0.293CS..EExtended strand (participates in β ladder)trans-147.1143.8175.9-173.50000110.8L13 E81 V82L13-S15 PolarHBondContact O-N 2.9Å; S15-E81 WeakPolarHBondContact OG-CG 3.33Å; S15-E81 PolarHBondContact OG-OE1 3.12Å; S15-V82 CarbonylContact C-O 3.31Å; S15-V82 WeakPolarHBondContact CA-O 3.27Å
16L89.8Confident76.5Confident11 Ų1145.6 Ų45.66%0.05828%0.281CS..EExtended strand (participates in β ladder)trans-140.6135.2174.8174.666.2000109.2L13 I18 V82 V87 L91 L125L13-L16 HydrophobicContact CD1-CB 4.48Å; L13-L16 HydrophobicContact CD1-CD1 4.26Å; L16-I18 HydrophobicContact CD2-CG1 4.45Å; L16-V82 HydrophobicContact CB-CG2 3.98Å; L16-V82 HydrophobicContact CG-CG2 4.49Å; L16-V82 PolarHBondContact N-O 3.37Å; L16-V82 VanDerWaalsContact O-CG2 3.26Å; L16-V82 WeakPolarHBondContact O-CG2 3.4Å; L16-V82 PolarHBondContact O-N 2.93Å; L16-V87 HydrophobicContact CB-CG1 4.37Å; L16-V87 HydrophobicContact CB-CG2 4.41Å; L16-V87 HydrophobicContact CD2-CG1 4.23Å; L16-L91 HydrophobicContact CD2-CD1 4.39Å; L16-L91 HydrophobicContact CD2-CD2 4.02Å; L16-L91 HydrophobicContact CD2-CG 4.4Å; L16-L125 HydrophobicContact CD1-CB 4.19Å; L16-L125 HydrophobicContact CD2-CB 4.42Å; L16-L125 HydrophobicContact CD2-CD2 4.12Å
17W93.6Very high78.2Confident31 Ų3148 Ų4812%0.11729%0.291CS..EExtended strand (participates in β ladder)trans-92140169.2-6888.4000110.4S34 Q36 A79 F80 E81 Q122 A124 L125W17-S34 WeakPolarHBondContact CH2-OG 3.13Å; W17-Q36 HydrophobicContact CH2-CG 4.07Å; W17-Q36 HydrophobicContact CZ3-CB 4.45Å; W17-Q36 HydrophobicContact CZ3-CG 4.24Å; W17-A79 HydrophobicContact CE3-CB 3.63Å; W17-A79 HydrophobicContact CZ3-CB 4.19Å; W17-F80 CarbonylContact C-O 3.55Å; W17-F80 VanDerWaalsContact CA-O 3.32Å; W17-F80 WeakPolarHBondContact CA-O 3.35Å; W17-E81 HydrophobicContact CD2-CB 3.92Å; W17-E81 HydrophobicContact CD2-CG 4.3Å; W17-E81 HydrophobicContact CE3-CB 3.88Å; W17-E81 HydrophobicContact CH2-CB 3.69Å; W17-E81 HydrophobicContact CH2-CG 4.4Å; W17-E81 HydrophobicContact CZ2-CB 3.69Å; W17-E81 HydrophobicContact CZ2-CG 3.9Å; W17-E81 HydrophobicContact CZ3-CB 3.78Å; W17-Q122 VanDerWaalsContact CD2-OE1 3.28Å; W17-Q122 HydrophobicContact CG-CB 4.49Å; W17-Q122 VanDerWaalsContact CZ2-OE1 3.23Å; W17-A124 HydrophobicContact CB-CB 3.9Å; W17-A124 CarbonylContact O-C 3.58Å; W17-A124 WeakPolarHBondContact O-CA 3.15Å; W17-L125 PolarHBondContact O-N 3.2Å
18I94Very high79.7Confident0 Ų047.1 Ų47.10%029%0.288CS..EExtended strand (participates in β ladder)trans-119.2122.2174.5-63.5161.6000107.8L16 L24 F30 A79 F80 V82 L94 L125L16-I18 HydrophobicContact CD2-CG1 4.45Å; I18-L24 HydrophobicContact CG2-CD1 4.47Å; I18-F30 HydrophobicContact CB-CZ 4.48Å; I18-F30 HydrophobicContact CD1-CE2 4.29Å; I18-F30 HydrophobicContact CD1-CZ 4.25Å; I18-F30 HydrophobicContact CG2-CZ 4.41Å; I18-A79 CarbonylContact O-C 3.23Å; I18-A79 WeakPolarHBondContact O-CA 3.43Å; I18-F80 PolarHBondContact N-O 2.9Å; I18-F80 PolarHBondContact O-N 2.86Å; I18-V82 HydrophobicContact CD1-CG1 4.12Å; I18-V82 HydrophobicContact CD1-CG2 3.85Å; I18-V82 HydrophobicContact CG1-CG2 4.45Å; I18-L94 HydrophobicContact CD1-CD1 3.8Å; I18-L94 HydrophobicContact CG1-CD1 4.44Å; I18-L94 HydrophobicContact CG2-CD1 3.9Å; I18-L125 WeakPolarHBondContact CA-O 3.31Å
19F96.6Very high81.4Confident2 Ų247.2 Ų47.21%0.00928%0.276CS..EExtended strand (participates in β ladder)trans-91.7125.6-179.1-174.6-102.8000111.7Y21 I40 A79 F111 A124 L125 L126F19-Y21 HydrophobicContact CD1-CD1 4.33Å; F19-Y21 HydrophobicContact CE1-CD1 4.48Å; F19-I40 HydrophobicContact CD1-CD1 3.88Å; F19-I40 HydrophobicContact CD1-CG1 4.36Å; F19-I40 HydrophobicContact CD1-CG2 4.04Å; F19-I40 HydrophobicContact CD2-CG2 4.02Å; F19-I40 HydrophobicContact CE1-CB 4.47Å; F19-I40 HydrophobicContact CE1-CD1 3.6Å; F19-I40 HydrophobicContact CE1-CG1 3.73Å; F19-I40 HydrophobicContact CE1-CG2 3.95Å; F19-I40 HydrophobicContact CE2-CG2 3.97Å; F19-I40 HydrophobicContact CG-CG2 4.04Å; F19-I40 HydrophobicContact CZ-CD1 4.39Å; F19-I40 HydrophobicContact CZ-CG1 4.03Å; F19-I40 HydrophobicContact CZ-CG2 3.92Å; F19-A79 HydrophobicContact CD2-CB 4.43Å; F19-F111 AromaticContact CD2-CD2 3.56Å; F19-F111 HydrophobicContact CD2-CD2 3.56Å; F19-F111 AromaticContact CD2-CE2 3.96Å; F19-F111 HydrophobicContact CD2-CE2 3.96Å; F19-F111 HydrophobicContact CD2-CG 4.45Å; F19-F111 AromaticContact CE2-CD2 3.64Å; F19-F111 HydrophobicContact CE2-CD2 3.64Å; F19-F111 AromaticContact CE2-CE2 3.8Å; F19-F111 HydrophobicContact CE2-CE2 3.8Å; F19-A124 HydrophobicContact CB-CB 3.96Å; F19-L125 PolarHBondContact N-O 2.86Å; F19-L126 HydrophobicContact CD1-CD1 3.92Å
20G96.1Very high83.2Confident1 Ų145 Ų451%0.0125%0.248CC..EExtended strand (participates in β ladder)trans-108.4123.8176.100000112.1V25 G77 V78G20-V25 VanDerWaalsContact O-CG1 3.27Å; G20-V25 WeakPolarHBondContact O-CG1 3.46Å; G20-G77 VanDerWaalsContact O-CA 3.23Å; G20-G77 WeakPolarHBondContact O-CA 3.5Å; G20-V78 PolarHBondContact N-O 2.77Å; G20-V78 PolarHBondContact O-N 2.84Å
21Y96.2Very high85Confident18 Ų1846.9 Ų46.97%0.07126%0.256CS..SBendtrans-118.8-9.6176.859.7-90.8000113.9F19 R45 V65 L67 L126 Y127F19-Y21 HydrophobicContact CD1-CD1 4.33Å; F19-Y21 HydrophobicContact CE1-CD1 4.48Å; Y21-R45 WeakPolarHBondContact O-CD 3.4Å; Y21-R45 PolarHBondContact O-NH1 3.39Å; Y21-V65 HydrophobicContact CD2-CG2 3.85Å; Y21-V65 HydrophobicContact CE2-CG2 4.07Å; Y21-L67 HydrophobicContact CD1-CD1 3.73Å; Y21-L67 HydrophobicContact CD1-CD2 4.31Å; Y21-L67 HydrophobicContact CD1-CG 3.98Å; Y21-L67 HydrophobicContact CD2-CD1 4.47Å; Y21-L67 HydrophobicContact CD2-CD2 3.65Å; Y21-L67 HydrophobicContact CD2-CG 3.84Å; Y21-L67 HydrophobicContact CE1-CD1 3.85Å; Y21-L67 HydrophobicContact CE1-CG 3.95Å; Y21-L67 HydrophobicContact CE2-CD2 4.09Å; Y21-L67 HydrophobicContact CE2-CG 3.82Å; Y21-L67 HydrophobicContact CG-CD1 4.05Å; Y21-L67 HydrophobicContact CG-CD2 3.77Å; Y21-L67 HydrophobicContact CG-CG 3.92Å; Y21-L126 HydrophobicContact CD1-CD1 3.6Å; Y21-L126 HydrophobicContact CE1-CD1 3.52Å; Y21-Y127 WeakPolarHBondContact CE1-O 3.35Å; Y21-Y127 VanDerWaalsContact CZ-O 3.31Å; Y21-Y127 PolarHBondContact OH-O 3.45Å
22G95.2Very high87.4Confident7 Ų744.5 Ų44.57%0.07223%0.231CC..SBendtrans-120.8-130.5177.500000110.7L24 V25 V65G22-L24 PolarHBondContact O-N 2.97Å; G22-V25 VanDerWaalsContact O-CG2 3.31Å; G22-V25 WeakPolarHBondContact O-CG2 3.48Å; G22-V25 PolarHBondContact O-N 3.42Å; G22-V25 VanDerWaalsContact O-N 3.1Å; G22-V65 VanDerWaalsContact CA-CG2 3.45Å
23S93.5Very high89.5Confident21 Ų2145.9 Ų45.915%0.14723%0.225CC..G310 helixtrans-57.5-23.3-174.860.70000116.3V25 W26 K27 R97S23-V25 PolarHBondContact O-N 2.59Å; S23-W26 VanDerWaalsContact CA-CZ3 3.47Å; S23-W26 PolarHBondContact O-N 2.99Å; S23-K27 CarbonylContact O-C 3.51Å; S23-K27 WeakPolarHBondContact O-CA 3.24Å; S23-K27 PolarHBondContact O-N 2.81Å; S23-R97 PolarHBondContact OG-NH2 2.88Å
24L93.3Very high91.1Very high21 Ų2145.2 Ų45.211%0.1122%0.224CC..G310 helixtrans-60.5-26179.1-66.8-179000112.5I18 G22 W26 F30 F80 L94I18-L24 HydrophobicContact CG2-CD1 4.47Å; G22-L24 PolarHBondContact O-N 2.97Å; L24-W26 PolarHBondContact O-N 3.35Å; L24-F30 HydrophobicContact CD2-CE1 4.02Å; L24-F80 HydrophobicContact CB-CE2 4.31Å; L24-F80 VanDerWaalsContact O-CZ 3.26Å; L24-F80 WeakPolarHBondContact O-CZ 3.38Å; L24-L94 HydrophobicContact CD2-CD2 4.41Å
25V96Very high92.2Very high19 Ų1942.8 Ų42.812%0.11521%0.211CC..G310 helixtrans-65.1-22-179.6-51.90000113.3G20 G22 S23 V78 L166 F169G20-V25 VanDerWaalsContact O-CG1 3.27Å; G20-V25 WeakPolarHBondContact O-CG1 3.46Å; G22-V25 VanDerWaalsContact O-CG2 3.31Å; G22-V25 WeakPolarHBondContact O-CG2 3.48Å; G22-V25 PolarHBondContact O-N 3.42Å; G22-V25 VanDerWaalsContact O-N 3.1Å; S23-V25 PolarHBondContact O-N 2.59Å; V25-V78 HydrophobicContact CB-CG2 4.07Å; V25-V78 HydrophobicContact CG1-CG2 4.14Å; V25-L166 HydrophobicContact CG2-CD1 4.07Å; V25-F169 HydrophobicContact CB-CD1 4.04Å; V25-F169 HydrophobicContact CB-CD2 3.87Å; V25-F169 HydrophobicContact CB-CE1 4.19Å; V25-F169 HydrophobicContact CB-CE2 4.02Å; V25-F169 HydrophobicContact CB-CG 3.88Å; V25-F169 HydrophobicContact CB-CZ 4.19Å; V25-F169 HydrophobicContact CG1-CD1 4.21Å; V25-F169 HydrophobicContact CG1-CE1 4.01Å; V25-F169 HydrophobicContact CG1-CE2 4.49Å; V25-F169 HydrophobicContact CG1-CZ 4.17Å; V25-F169 HydrophobicContact CG2-CB 3.81Å; V25-F169 HydrophobicContact CG2-CD1 3.81Å; V25-F169 HydrophobicContact CG2-CD2 4.01Å; V25-F169 HydrophobicContact CG2-CE1 4.44Å; V25-F169 HydrophobicContact CG2-CG 3.57Å
26W94.2Very high92.8Very high59 Ų5944.3 Ų44.322%0.22322%0.215CC..THydrogen-bonded Turntrans-123.5-19.1174.674.584.5000114S23 L24 Y162 R165 L166S23-W26 VanDerWaalsContact CA-CZ3 3.47Å; S23-W26 PolarHBondContact O-N 2.99Å; L24-W26 PolarHBondContact O-N 3.35Å; W26-Y162 HydrophobicContact CH2-CD1 4.31Å; W26-Y162 AromaticContact CH2-CD2 3.5Å; W26-Y162 HydrophobicContact CH2-CD2 3.5Å; W26-Y162 VanDerWaalsContact CH2-CD2 3.5Å; W26-Y162 HydrophobicContact CH2-CE1 4.47Å; W26-Y162 AromaticContact CH2-CE2 3.72Å; W26-Y162 HydrophobicContact CH2-CE2 3.72Å; W26-Y162 AromaticContact CH2-CG 3.82Å; W26-Y162 HydrophobicContact CH2-CG 3.82Å; W26-Y162 AromaticContact CZ2-CD2 3.81Å; W26-Y162 HydrophobicContact CZ2-CD2 3.81Å; W26-Y162 HydrophobicContact CZ2-CE2 4.28Å; W26-Y162 HydrophobicContact CZ2-CG 4.31Å; W26-R165 VanDerWaalsContact CD1-CD 3.49Å; W26-R165 HydrophobicContact CD2-CB 3.73Å; W26-R165 HydrophobicContact CD2-CG 4.49Å; W26-R165 HydrophobicContact CE3-CB 3.81Å; W26-R165 HydrophobicContact CG-CB 4.2Å; W26-R165 HydrophobicContact CH2-CB 4.22Å; W26-R165 HydrophobicContact CZ2-CB 4.16Å; W26-R165 HydrophobicContact CZ3-CB 4.06Å; W26-R165 VanDerWaalsContact NE1-CD 3.26Å; W26-L166 HydrophobicContact CZ3-CB 4.01Å
27K91.8Very high93.2Very high79 Ų7945.6 Ų45.634%0.34322%0.223SC..  trans-138.873.8-175.2-172.5169.2176.1171.90110.2S23 D29S23-K27 CarbonylContact O-C 3.51Å; S23-K27 WeakPolarHBondContact O-CA 3.24Å; S23-K27 PolarHBondContact O-N 2.81Å; K27-D29 WeakPolarHBondContact CE-OD2 3.41Å; K27-D29 VanDerWaalsContact CG-OD1 3.25Å; K27-D29 WeakPolarHBondContact CG-OD1 3.4Å; K27-D29 WeakPolarHBondContact CG-OD2 3.43Å; K27-D29 IonicContact NZ-OD2 2.76Å
28P88.3Confident93.3Very high22 Ų2244.1 Ų44.114%0.14322%0.217CC..  trans-68.1-37.3177.625.2-32.2000112.1F30 Y32 F80P28-F30 HydrophobicContact CB-CD1 4.3Å; P28-F30 HydrophobicContact CB-CE1 3.95Å; P28-F30 HydrophobicContact CB-CZ 4.07Å; P28-F30 WeakPolarHBondContact O-CD1 3.16Å; P28-F30 WeakPolarHBondContact O-CE1 3.38Å; P28-F30 PolarHBondContact O-N 2.8Å; P28-F30 VanDerWaalsContact O-N 3.14Å; P28-Y32 HydrophobicContact CB-CE1 4.43Å; P28-Y32 HydrophobicContact CG-CE1 3.88Å; P28-F80 HydrophobicContact CB-CD1 4.48Å; P28-F80 HydrophobicContact CB-CE1 4.09Å; P28-F80 HydrophobicContact CB-CE2 4.49Å; P28-F80 HydrophobicContact CB-CZ 4.09Å; P28-F80 HydrophobicContact CG-CE1 4.15Å; P28-F80 HydrophobicContact CG-CZ 4.37Å
29D87.3Confident93.5Very high87 Ų8746.4 Ų46.447%0.46523%0.226SC..  trans56.221.4179.6-70.4-12.3000115.2K27 Y93K27-D29 WeakPolarHBondContact CE-OD2 3.41Å; K27-D29 VanDerWaalsContact CG-OD1 3.25Å; K27-D29 WeakPolarHBondContact CG-OD1 3.4Å; K27-D29 WeakPolarHBondContact CG-OD2 3.43Å; K27-D29 IonicContact NZ-OD2 2.76Å; D29-Y93 HydrophobicContact CB-CE1 4.2Å; D29-Y93 VanDerWaalsContact CB-OH 3.32Å; D29-Y93 WeakPolarHBondContact CB-OH 3.21Å
30F86.1Confident93.5Very high23 Ų2346.3 Ų46.310%0.10123%0.226CC..SBendtrans-135.9161.2169.657.7-99.2000111I18 L24 P28 Y32 F80 V82 Y93 L94I18-F30 HydrophobicContact CB-CZ 4.48Å; I18-F30 HydrophobicContact CD1-CE2 4.29Å; I18-F30 HydrophobicContact CD1-CZ 4.25Å; I18-F30 HydrophobicContact CG2-CZ 4.41Å; L24-F30 HydrophobicContact CD2-CE1 4.02Å; P28-F30 HydrophobicContact CB-CD1 4.3Å; P28-F30 HydrophobicContact CB-CE1 3.95Å; P28-F30 HydrophobicContact CB-CZ 4.07Å; P28-F30 WeakPolarHBondContact O-CD1 3.16Å; P28-F30 WeakPolarHBondContact O-CE1 3.38Å; P28-F30 PolarHBondContact O-N 2.8Å; P28-F30 VanDerWaalsContact O-N 3.14Å; F30-Y32 HydrophobicContact CD2-CD1 4.48Å; F30-Y32 HydrophobicContact CE2-CD1 4.35Å; F30-F80 HydrophobicContact CE2-CB 3.79Å; F30-F80 HydrophobicContact CE2-CG 4.19Å; F30-F80 HydrophobicContact CZ-CB 3.95Å; F30-F80 HydrophobicContact CZ-CD2 4.1Å; F30-F80 HydrophobicContact CZ-CG 4.02Å; F30-V82 HydrophobicContact CD2-CG1 3.9Å; F30-V82 HydrophobicContact CE2-CG1 3.83Å; F30-Y93 HydrophobicContact CD1-CD1 4.4Å; F30-L94 HydrophobicContact CE1-CD1 4.5Å; F30-L94 HydrophobicContact CE1-CD2 4.48Å
31K88.5Confident93.5Very high150 Ų15051 Ų5165%0.65225%0.247SC*.  trans-79.5130.5176.5-67.4-179.9-179.1174.10109.8Q86K31-Q86 HydrophobicContact CB-CG 4.48Å
32Y92.5Very high93.4Very high93 Ų9350.9 Ų50.937%0.36525%0.251SS..  trans-133.6155.5175.360.1-90.9000109.9P28 F30 S34 F80 E81P28-Y32 HydrophobicContact CB-CE1 4.43Å; P28-Y32 HydrophobicContact CG-CE1 3.88Å; F30-Y32 HydrophobicContact CD2-CD1 4.48Å; F30-Y32 HydrophobicContact CE2-CD1 4.35Å; Y32-S34 WeakPolarHBondContact CD2-O 3.43Å; Y32-F80 AromaticContact CD1-CD1 3.73Å; Y32-F80 HydrophobicContact CD1-CD1 3.73Å; Y32-F80 HydrophobicContact CD1-CE1 4.35Å; Y32-F80 AromaticContact CD2-CD1 3.96Å; Y32-F80 HydrophobicContact CD2-CD1 3.96Å; Y32-F80 AromaticContact CE1-CD1 3.78Å; Y32-F80 HydrophobicContact CE1-CD1 3.78Å; Y32-F80 AromaticContact CE1-CE1 3.97Å; Y32-F80 HydrophobicContact CE1-CE1 3.97Å; Y32-F80 AromaticContact CE2-CD1 3.99Å; Y32-F80 HydrophobicContact CE2-CD1 3.99Å; Y32-F80 HydrophobicContact CE2-CE1 4.42Å; Y32-F80 HydrophobicContact CG-CB 4.29Å; Y32-F80 AromaticContact CG-CD1 3.82Å; Y32-F80 HydrophobicContact CG-CD1 3.82Å; Y32-F80 AromaticContact CZ-CD1 3.91Å; Y32-F80 AromaticContact CZ-CE1 3.99Å; Y32-E81 CarbonylContact C-O 3.54Å; Y32-E81 WeakPolarHBondContact CA-O 3.38Å; Y32-E81 WeakPolarHBondContact CB-O 3.5Å
33K93.1Very high93.5Very high129 Ų12951.6 Ų51.656%0.56125%0.252SS*.SBendtrans-82.4-42.7179.4174.8-179.3158.6-132.90111.6E81 T83K33-E81 WeakPolarHBondContact CD-OE2 3.44Å; K33-E81 WeakPolarHBondContact CE-OE2 3.27Å; K33-E81 PolarHBondContact N-O 2.83Å; K33-E81 IonicContact NZ-OE1 2.61Å; K33-E81 PolarHBondContact NZ-OE1 2.72Å; K33-E81 IonicContact NZ-OE2 3.36Å; K33-E81 PolarHBondContact NZ-OE2 3.5Å; K33-T83 HydrophobicContact CB-CG2 4.34Å; K33-T83 HydrophobicContact CD-CG2 3.69Å
34S92.8Very high93.6Very high35 Ų3553 Ų5325%0.24526%0.255CS..EExtended strand (participates in β ladder)trans-149.7161.1-18069.90000110.9W17 Y32 E81W17-S34 WeakPolarHBondContact CH2-OG 3.13Å; Y32-S34 WeakPolarHBondContact CD2-O 3.43Å; S34-E81 PolarHBondContact O-N 2.93Å; S34-E81 VanDerWaalsContact OG-CB 3.25Å; S34-E81 WeakPolarHBondContact OG-CB 3.3Å; S34-E81 PolarHBondContact OG-OE2 2.66Å
35S94.9Very high93.8Very high55 Ų5552.5 Ų52.539%0.38525%0.252SS..EExtended strand (participates in β ladder)trans-141143.9175.560.60000110.8A79S35-A79 CarbonylContact C-O 3.53Å; S35-A79 WeakPolarHBondContact CA-O 3.23Å
36Q95.7Very high93.9Very high68 Ų6854.3 Ų54.332%0.31826%0.257SS..EExtended strand (participates in β ladder)trans-134.7137.2-178.8-65.7-1790.200110.3W17 V78 A79 F111 P113 Q122W17-Q36 HydrophobicContact CH2-CG 4.07Å; W17-Q36 HydrophobicContact CZ3-CB 4.45Å; W17-Q36 HydrophobicContact CZ3-CG 4.24Å; Q36-V78 CarbonylContact O-C 3.53Å; Q36-V78 WeakPolarHBondContact O-CA 3.22Å; Q36-A79 PolarHBondContact N-O 2.86Å; Q36-A79 PolarHBondContact O-N 3.47Å; Q36-F111 HydrophobicContact CB-CE1 4.1Å; Q36-F111 HydrophobicContact CB-CZ 4.15Å; Q36-F111 WeakPolarHBondContact O-CZ 3.33Å; Q36-P113 VanDerWaalsContact OE1-CG 3.23Å; Q36-Q122 VanDerWaalsContact OE1-NE2 3.1Å
37V96.9Very high94.1Very high38 Ų3851.5 Ų51.523%0.2325%0.246CC..EExtended strand (participates in β ladder)trans-78143.4168.1178.30000108.2W76 G77 V78 E114 F169V37-W76 HydrophobicContact CG1-CE3 4.2Å; V37-W76 HydrophobicContact CG1-CZ3 4.34Å; V37-G77 WeakPolarHBondContact CA-O 3.49Å; V37-V78 HydrophobicContact CG2-CG2 4.36Å; V37-E114 WeakPolarHBondContact CG1-OE2 3.1Å; V37-E114 PolarHBondContact O-N 3.01Å; V37-F169 HydrophobicContact CG2-CE2 4.45Å
38G96.5Very high94.3Very high0 Ų049.6 Ų49.60%024%0.237CC..EExtended strand (participates in β ladder)trans172.7-158.1178.800000110.6W76 G77 F111 I112G38-W76 WeakPolarHBondContact O-CA 3.2Å; G38-G77 PolarHBondContact N-O 2.97Å; G38-G77 VanDerWaalsContact N-O 3.16Å; G38-G77 PolarHBondContact O-N 2.87Å; G38-F111 VanDerWaalsContact C-CE2 3.46Å; G38-F111 VanDerWaalsContact CA-CE2 3.44Å; G38-I112 CarbonylContact C-O 3.58Å; G38-I112 WeakPolarHBondContact CA-O 3.39Å
39Y97.1Very high94.7Very high48 Ų4848.7 Ų48.719%0.18823%0.231CC..EExtended strand (participates in β ladder)trans-144.3166.9-172.360.8-90.2000114.2H41 T74 T75 W76 F111 I112Y39-H41 AromaticContact CD2-CE1 3.92Å; Y39-H41 AromaticContact CE2-CE1 3.42Å; Y39-H41 VanDerWaalsContact CE2-CE1 3.42Å; Y39-H41 WeakPolarHBondContact CE2-CE1 3.37Å; Y39-H41 AromaticContact CE2-NE2 3.47Å; Y39-H41 WeakPolarHBondContact CE2-NE2 3.4Å; Y39-T74 HydrophobicContact CD2-CG2 3.39Å; Y39-T74 HydrophobicContact CE2-CG2 4.23Å; Y39-T74 HydrophobicContact CG-CG2 3.58Å; Y39-T75 VanDerWaalsContact CA-O 3.25Å; Y39-T75 WeakPolarHBondContact CA-O 3.11Å; Y39-T75 WeakPolarHBondContact CB-O 3.05Å; Y39-W76 HydrophobicContact CD1-CD2 4.16Å; Y39-W76 AromaticContact CD1-CE2 3.63Å; Y39-W76 HydrophobicContact CD1-CE3 4.4Å; Y39-W76 AromaticContact CD1-CH2 3.69Å; Y39-W76 HydrophobicContact CD1-CH2 3.69Å; Y39-W76 AromaticContact CD1-CZ2 3.37Å; Y39-W76 HydrophobicContact CD1-CZ2 3.37Å; Y39-W76 HydrophobicContact CD1-CZ3 4.2Å; Y39-W76 HydrophobicContact CE1-CH2 4.13Å; Y39-W76 AromaticContact CE1-CZ2 3.87Å; Y39-W76 HydrophobicContact CE1-CZ2 3.87Å; Y39-W76 HydrophobicContact CG-CD2 4.44Å; Y39-W76 HydrophobicContact CG-CZ2 4.22Å; Y39-F111 WeakPolarHBondContact O-CA 3.2Å; Y39-I112 HydrophobicContact CD2-CB 4.29Å; Y39-I112 HydrophobicContact CD2-CD1 4.18Å; Y39-I112 HydrophobicContact CE1-CB 4.11Å; Y39-I112 HydrophobicContact CE1-CG2 3.9Å; Y39-I112 HydrophobicContact CE2-CB 3.85Å; Y39-I112 HydrophobicContact CE2-CD1 3.43Å; Y39-I112 VanDerWaalsContact CE2-CD1 3.43Å; Y39-I112 HydrophobicContact CE2-CG1 4.23Å; Y39-I112 HydrophobicContact CE2-CG2 4.2Å; Y39-I112 PolarHBondContact N-O 3.5Å; Y39-I112 PolarHBondContact O-N 3.16Å; Y39-I112 WeakPolarHBondContact OH-CG2 3.48Å
40I96.9Very high95Very high0 Ų044.6 Ų44.60%021%0.209CC..EExtended strand (participates in β ladder)trans-124.2150.717064.1171.4000109.2F19 Y43 L67 T74 T75 V109 F111 L126F19-I40 HydrophobicContact CD1-CD1 3.88Å; F19-I40 HydrophobicContact CD1-CG1 4.36Å; F19-I40 HydrophobicContact CD1-CG2 4.04Å; F19-I40 HydrophobicContact CD2-CG2 4.02Å; F19-I40 HydrophobicContact CE1-CB 4.47Å; F19-I40 HydrophobicContact CE1-CD1 3.6Å; F19-I40 HydrophobicContact CE1-CG1 3.73Å; F19-I40 HydrophobicContact CE1-CG2 3.95Å; F19-I40 HydrophobicContact CE2-CG2 3.97Å; F19-I40 HydrophobicContact CG-CG2 4.04Å; F19-I40 HydrophobicContact CZ-CD1 4.39Å; F19-I40 HydrophobicContact CZ-CG1 4.03Å; F19-I40 HydrophobicContact CZ-CG2 3.92Å; I40-Y43 HydrophobicContact CD1-CD2 3.8Å; I40-Y43 HydrophobicContact CD1-CG 4.33Å; I40-Y43 HydrophobicContact CG1-CD2 4.44Å; I40-L67 HydrophobicContact CD1-CD1 3.88Å; I40-T74 WeakPolarHBondContact O-CA 3.26Å; I40-T75 PolarHBondContact N-O 3.16Å; I40-T75 PolarHBondContact O-N 2.78Å; I40-V109 HydrophobicContact CB-CG2 4.42Å; I40-V109 HydrophobicContact CD1-CG2 4.45Å; I40-V109 HydrophobicContact CG2-CG2 3.76Å; I40-F111 HydrophobicContact CG2-CB 4.4Å; I40-F111 HydrophobicContact CG2-CD2 4.49Å; I40-L126 HydrophobicContact CD1-CD1 4.33Å; I40-L126 HydrophobicContact CD1-CD2 3.76Å
41H95.9Very high95.3Very high100 Ų10044.6 Ų44.646%0.46321%0.21SC..EExtended strand (participates in β ladder)trans-96.7163.2173.3-65.8-57.9000112.3Y39 Y43 A73 T74 I112Y39-H41 AromaticContact CD2-CE1 3.92Å; Y39-H41 AromaticContact CE2-CE1 3.42Å; Y39-H41 VanDerWaalsContact CE2-CE1 3.42Å; Y39-H41 WeakPolarHBondContact CE2-CE1 3.37Å; Y39-H41 AromaticContact CE2-NE2 3.47Å; Y39-H41 WeakPolarHBondContact CE2-NE2 3.4Å; H41-Y43 VanDerWaalsContact O-CD2 3.24Å; H41-Y43 WeakPolarHBondContact O-CD2 3.22Å; H41-A73 CarbonylContact C-O 3.52Å; H41-A73 WeakPolarHBondContact CA-O 2.89Å; H41-T74 PolarHBondContact ND1-OG1 3.46Å; H41-I112 WeakPolarHBondContact NE2-CD1 3.44Å
42G95.7Very high95.5Very high14 Ų1439.7 Ų39.714%0.14419%0.191CC..EExtended strand (participates in β ladder)trans84.38.3173.500000114.4E69 D70 A73G42-E69 WeakPolarHBondContact O-CA 3.49Å; G42-D70 CarbonylContact C-O 3.01Å; G42-D70 WeakPolarHBondContact CA-O 3.49Å; G42-D70 PolarHBondContact O-N 3.2Å; G42-A73 PolarHBondContact N-O 2.87Å
43Y96.4Very high95.4Very high23 Ų2339.5 Ų39.59%0.0919%0.192CC..EExtended strand (participates in β ladder)trans-143.2138.1-176.2-62.5-81.4000112.5I40 H41 L67 I68 E69 D70 A73 T75 K107 V109 L126 I128I40-Y43 HydrophobicContact CD1-CD2 3.8Å; I40-Y43 HydrophobicContact CD1-CG 4.33Å; I40-Y43 HydrophobicContact CG1-CD2 4.44Å; H41-Y43 VanDerWaalsContact O-CD2 3.24Å; H41-Y43 WeakPolarHBondContact O-CD2 3.22Å; Y43-L67 HydrophobicContact CD1-CB 3.91Å; Y43-L67 HydrophobicContact CD1-CD1 4.38Å; Y43-L67 HydrophobicContact CG-CB 4.29Å; Y43-L67 HydrophobicContact CG-CD1 4.14Å; Y43-I68 CarbonylContact C-O 3.58Å; Y43-I68 WeakPolarHBondContact CA-O 3.47Å; Y43-E69 HydrophobicContact CD1-CG 4.17Å; Y43-E69 HydrophobicContact CE1-CG 3.66Å; Y43-D70 PolarHBondContact N-O 2.98Å; Y43-A73 WeakPolarHBondContact O-CB 3.37Å; Y43-T75 PolarHBondContact O-OG1 2.87Å; Y43-K107 WeakPolarHBondContact OH-CD 3.45Å; Y43-K107 PolarHBondContact OH-NZ 3.46Å; Y43-V109 HydrophobicContact CE2-CG1 3.99Å; Y43-L126 HydrophobicContact CD2-CD2 4.39Å; Y43-L126 HydrophobicContact CE2-CD2 4.19Å; Y43-I128 HydrophobicContact CD1-CD1 4.08Å; Y43-I128 HydrophobicContact CE1-CD1 3.55Å
44K96.1Very high95.3Very high50 Ų5035.9 Ų35.922%0.21718%0.177CC..EExtended strand (participates in β ladder)trans-109.1133.416864.1-177.4155.4-147.30111.3R46 L67 I68 D70 A73K44-R46 HydrophobicContact CG-CG 4.27Å; K44-L67 WeakPolarHBondContact O-CA 3.33Å; K44-I68 HydrophobicContact CD-CB 4.37Å; K44-I68 HydrophobicContact CG-CB 3.79Å; K44-I68 WeakPolarHBondContact CG-O 3.46Å; K44-I68 PolarHBondContact N-O 3.08Å; K44-I68 PolarHBondContact O-N 2.94Å; K44-D70 HydrophobicContact CB-CB 4.31Å; K44-D70 HydrophobicContact CD-CB 4.02Å; K44-D70 WeakPolarHBondContact CD-OD2 3.3Å; K44-D70 WeakPolarHBondContact CE-OD2 3.38Å; K44-D70 HydrophobicContact CG-CB 4.04Å; K44-D70 IonicContact NZ-OD2 2.59Å; K44-D70 PolarHBondContact NZ-OD2 3.15Å; K44-A73 HydrophobicContact CB-CB 3.92Å
45R97.6Very high95.4Very high10 Ų1034.7 Ų34.74%0.03817%0.167CC..EExtended strand (participates in β ladder)trans-77.6129174.9-177.9169.355.7-139.6-9.2112Y21 V65 L67 T75 W76 M170 D179Y21-R45 WeakPolarHBondContact O-CD 3.4Å; Y21-R45 PolarHBondContact O-NH1 3.39Å; R45-V65 HydrophobicContact CG-CB 3.72Å; R45-V65 HydrophobicContact CG-CG1 3.73Å; R45-V65 HydrophobicContact CG-CG2 4.13Å; R45-L67 HydrophobicContact CB-CD2 4.08Å; R45-T75 HydrophobicContact CB-CG2 4.1Å; R45-T75 PolarHBondContact N-OG1 2.86Å; R45-W76 PolarHBondContact NH1-O 2.91Å; R45-M170 PolarHBondContact NH2-SD 3.28Å; R45-D179 IonicContact CZ-OD2 3.41Å; R45-D179 IonicContact NE-OD2 3.15Å; R45-D179 PolarHBondContact NE-OD2 3.32Å; R45-D179 IonicContact NH2-OD2 3.41Å; R45-D179 PolarHBondContact NH2-OD2 2.77Å
46R98Very high95.4Very high57 Ų5732.1 Ų32.122%0.21515%0.149CC..EExtended strand (participates in β ladder)trans-142.2139.5-178.8-65.2-64.5179.5-94.44.9113K44 W48 V65 T66 I68 H181K44-R46 HydrophobicContact CG-CG 4.27Å; R46-W48 HydrophobicContact CB-CB 4.28Å; R46-W48 HydrophobicContact CB-CD2 3.51Å; R46-W48 HydrophobicContact CB-CE3 3.98Å; R46-W48 HydrophobicContact CB-CG 3.65Å; R46-W48 HydrophobicContact CB-CZ2 4.32Å; R46-W48 HydrophobicContact CG-CD2 3.9Å; R46-W48 HydrophobicContact CG-CE3 4.09Å; R46-W48 HydrophobicContact CG-CH2 4.04Å; R46-W48 HydrophobicContact CG-CZ2 3.85Å; R46-W48 HydrophobicContact CG-CZ3 4.16Å; R46-W48 PolarHBondContact O-N 2.89Å; R46-V65 CarbonylContact O-C 3.51Å; R46-V65 VanDerWaalsContact O-CA 3.26Å; R46-V65 WeakPolarHBondContact O-CA 3.33Å; R46-T66 PolarHBondContact N-O 2.82Å; R46-T66 PolarHBondContact O-N 3.3Å; R46-I68 HydrophobicContact CB-CG1 4.22Å; R46-I68 HydrophobicContact CG-CG1 4.03Å; R46-H181 WeakPolarHBondContact CD-ND1 3.25Å
47F98.1Very high95.3Very high1 Ų131.9 Ų31.90%0.00415%0.15CC..EExtended strand (participates in β ladder)trans-76.347.9173.9-78.5-95.3000112.7R63 V64 V65 I145 I149 Y162 L163 L166 H181 L182 I185F47-R63 WeakPolarHBondContact O-CD 3.49Å; F47-R63 PolarHBondContact O-NH1 3.36Å; F47-V64 CarbonylContact C-O 3.5Å; F47-V64 WeakPolarHBondContact CA-O 3.2Å; F47-V65 HydrophobicContact CD1-CG1 4Å; F47-V65 HydrophobicContact CD2-CG1 3.6Å; F47-V65 HydrophobicContact CE1-CG1 3.89Å; F47-V65 HydrophobicContact CE2-CG1 3.46Å; F47-V65 VanDerWaalsContact CE2-CG1 3.46Å; F47-V65 HydrophobicContact CG-CG1 3.87Å; F47-V65 HydrophobicContact CZ-CG1 3.62Å; F47-I145 HydrophobicContact CB-CG2 3.84Å; F47-I149 HydrophobicContact CD1-CD1 3.58Å; F47-I149 HydrophobicContact CE1-CD1 3.87Å; F47-I149 HydrophobicContact CG-CD1 4.26Å; F47-Y162 AromaticContact CE1-CD1 3.88Å; F47-Y162 HydrophobicContact CE1-CD1 3.88Å; F47-Y162 AromaticContact CE1-CE1 3.79Å; F47-Y162 HydrophobicContact CE1-CE1 3.79Å; F47-Y162 HydrophobicContact CZ-CD1 4.48Å; F47-Y162 HydrophobicContact CZ-CE1 4.29Å; F47-L163 HydrophobicContact CE1-CB 4.5Å; F47-L163 HydrophobicContact CE1-CD1 4.04Å; F47-L163 HydrophobicContact CE2-CD1 3.96Å; F47-L163 HydrophobicContact CZ-CD1 3.45Å; F47-L163 VanDerWaalsContact CZ-CD1 3.45Å; F47-L166 HydrophobicContact CE2-CD2 4.26Å; F47-L166 HydrophobicContact CZ-CD2 3.95Å; F47-H181 AromaticContact CD2-CD2 3.9Å; F47-H181 AromaticContact CD2-NE2 3.75Å; F47-H181 PolarHBondContact N-NE2 3.34Å; F47-H181 VanDerWaalsContact N-NE2 3.19Å; F47-L182 HydrophobicContact CE2-CD1 3.55Å; F47-L182 HydrophobicContact CZ-CD1 3.79Å; F47-I185 HydrophobicContact CB-CD1 3.94Å; F47-I185 HydrophobicContact CD2-CD1 3.73Å; F47-I185 HydrophobicContact CG-CD1 4.06Å
48W97.1Very high95Very high38 Ų3836.4 Ų36.414%0.14417%0.173CC..EExtended strand (participates in β ladder)trans-104.91.3-172.3-62.7-8.4000113.2R46 I68 F136 L137 G138 P139 H181R46-W48 HydrophobicContact CB-CB 4.28Å; R46-W48 HydrophobicContact CB-CD2 3.51Å; R46-W48 HydrophobicContact CB-CE3 3.98Å; R46-W48 HydrophobicContact CB-CG 3.65Å; R46-W48 HydrophobicContact CB-CZ2 4.32Å; R46-W48 HydrophobicContact CG-CD2 3.9Å; R46-W48 HydrophobicContact CG-CE3 4.09Å; R46-W48 HydrophobicContact CG-CH2 4.04Å; R46-W48 HydrophobicContact CG-CZ2 3.85Å; R46-W48 HydrophobicContact CG-CZ3 4.16Å; R46-W48 PolarHBondContact O-N 2.89Å; W48-I68 HydrophobicContact CE3-CD1 3.78Å; W48-I68 HydrophobicContact CE3-CG1 3.65Å; W48-I68 HydrophobicContact CZ3-CD1 4.16Å; W48-I68 HydrophobicContact CZ3-CG1 3.72Å; W48-I68 HydrophobicContact CZ3-CG2 4.45Å; W48-F136 HydrophobicContact CB-CD2 4.5Å; W48-F136 HydrophobicContact CB-CE2 3.8Å; W48-F136 HydrophobicContact CB-CZ 4.25Å; W48-F136 HydrophobicContact CE3-CE2 4.43Å; W48-F136 HydrophobicContact CE3-CZ 4.08Å; W48-L137 PolarHBondContact O-N 3.47Å; W48-G138 VanDerWaalsContact CD1-O 3.3Å; W48-G138 PolarHBondContact O-N 3.4Å; W48-G138 VanDerWaalsContact O-N 3.12Å; W48-P139 HydrophobicContact CD2-CB 4.38Å; W48-P139 HydrophobicContact CD2-CG 4.16Å; W48-P139 HydrophobicContact CE3-CG 4.01Å; W48-P139 HydrophobicContact CH2-CB 4.1Å; W48-P139 HydrophobicContact CH2-CG 3.72Å; W48-P139 HydrophobicContact CZ2-CB 3.74Å; W48-P139 HydrophobicContact CZ2-CG 3.87Å; W48-P139 HydrophobicContact CZ3-CG 3.79Å; W48-H181 AromaticContact NE1-CE1 3.77Å
49H94.8Very high94.9Very high4 Ų443.3 Ų43.32%0.01921%0.21CC..EExtended strand (participates in β ladder)trans-102.7132177.3-163.2-92.3000110.7R63 V64 T66 A129 N133H49-R63 CarbonylContact O-C 3.56Å; H49-R63 WeakPolarHBondContact O-CA 3.47Å; H49-V64 HydrophobicContact CB-CG2 4.12Å; H49-V64 PolarHBondContact N-O 3.28Å; H49-V64 PolarHBondContact O-N 3.22Å; H49-T66 HydrophobicContact CB-CG2 4.1Å; H49-A129 WeakPolarHBondContact CD2-CB 3.32Å; H49-A129 WeakPolarHBondContact NE2-CB 3.48Å; H49-N133 PolarHBondContact NE2-ND2 3.16Å
50G94.5Very high94.8Very high1 Ų144.8 Ų44.81%0.0122%0.221CC..EExtended strand (participates in β ladder)trans-73.6148.3173.900000111.4G62 L135G50-G62 VanDerWaalsContact CA-O 3.3Å; G50-G62 WeakPolarHBondContact CA-O 3.16Å; G50-L135 WeakPolarHBondContact CA-O 3.33Å; G50-L135 PolarHBondContact N-O 3.48Å
51D92.6Very high94.7Very high23 Ų2346.4 Ų46.412%0.12323%0.231CC..EExtended strand (participates in β ladder)trans-132.4109.5170.6-177.7-72000109F53 H54 R55 G56 G62 V64D51-F53 PolarHBondContact OD1-N 2.73Å; D51-H54 WeakPolarHBondContact OD1-CA 3.5Å; D51-H54 PolarHBondContact OD1-N 2.85Å; D51-H54 IonicContact OD2-CD2 2.96Å; D51-R55 HydrophobicContact CB-CB 4.36Å; D51-R55 PolarHBondContact OD1-N 2.91Å; D51-G56 VanDerWaalsContact O-CA 3.24Å; D51-G56 WeakPolarHBondContact O-CA 3.33Å; D51-G56 PolarHBondContact O-N 3.31Å; D51-G56 VanDerWaalsContact O-N 3.08Å; D51-G62 PolarHBondContact N-O 2.91Å; D51-G62 PolarHBondContact O-N 2.91Å; D51-V64 HydrophobicContact CB-CG1 3.74Å; D51-V64 HydrophobicContact CB-CG2 4.02Å
52N92.6Very high94.7Very high46 Ų4641.6 Ų41.625%0.24621%0.209CC..SBendtrans-98.114.9-177.867.3-29.4000112.8G56 N57 D58N52-G56 CarbonylContact C-O 3.01Å; N52-N57 WeakPolarHBondContact CB-O 3.44Å; N52-N57 CarbonylContact O-C 3.38Å; N52-N57 WeakPolarHBondContact O-CA 3.48Å; N52-D58 PolarHBondContact ND2-OD1 2.97Å
53F90.3Very high94.8Very high89 Ų8941.6 Ų41.639%0.3921%0.205SC..SBendtrans-138-54.4-175.3-175.6-103.2000114D51 G56 K155D51-F53 PolarHBondContact OD1-N 2.73Å; F53-G56 CarbonylContact C-O 3.54Å; F53-G56 PolarHBondContact N-O 2.87Å; F53-K155 HydrophobicContact CE1-CD 3.81Å; F53-K155 HydrophobicContact CE2-CD 3.91Å; F53-K155 HydrophobicContact CZ-CD 3.38Å; F53-K155 WeakPolarHBondContact O-CB 3.42Å; F53-K155 PolarHBondContact O-N 3.29Å
54H90.6Very high94.8Very high53 Ų5340.8 Ų40.825%0.24520%0.202CC..SBendtrans-82.3-43.7-175.9-70.2-67.9000112.8D51 G154 K155 T156D51-H54 WeakPolarHBondContact OD1-CA 3.5Å; D51-H54 PolarHBondContact OD1-N 2.85Å; D51-H54 IonicContact OD2-CD2 2.96Å; H54-G154 CarbonylContact O-C 3.52Å; H54-G154 VanDerWaalsContact O-C 3.27Å; H54-G154 WeakPolarHBondContact O-CA 3.06Å; H54-K155 PolarHBondContact O-N 3.48Å; H54-T156 PolarHBondContact ND1-OG1 2.65Å; H54-T156 WeakPolarHBondContact O-CA 3.25Å; H54-T156 WeakPolarHBondContact O-CB 3.41Å; H54-T156 PolarHBondContact O-N 3.23Å
55R95Very high94.8Very high11 Ų1138.6 Ų38.64%0.04219%0.193CC..SBendtrans-120.5-8.9-172.2-59.2-55.9-178.1171.8-3.1113.2D51 V64 R152 Q153 G154 T156 H158 N159 E161 Y162D51-R55 HydrophobicContact CB-CB 4.36Å; D51-R55 PolarHBondContact OD1-N 2.91Å; R55-V64 HydrophobicContact CB-CG1 4.38Å; R55-V64 HydrophobicContact CG-CG1 4.1Å; R55-R152 CarbonylContact O-C 3.56Å; R55-Q153 CarbonylContact O-C 3.54Å; R55-Q153 VanDerWaalsContact O-C 3.31Å; R55-Q153 WeakPolarHBondContact O-CA 3.42Å; R55-Q153 PolarHBondContact O-N 3Å; R55-G154 VanDerWaalsContact C-N 3.32Å; R55-G154 PolarHBondContact O-N 2.95Å; R55-T156 PolarHBondContact NH1-O 2.91Å; R55-H158 PolarHBondContact NH1-O 2.87Å; R55-N159 HydrophobicContact CB-CB 4.02Å; R55-E161 IonicContact CZ-OE2 3.42Å; R55-E161 IonicContact NH1-OE2 2.7Å; R55-E161 PolarHBondContact NH1-OE2 2.92Å; R55-E161 IonicContact NH2-OE2 3.29Å; R55-Y162 HydrophobicContact CG-CD2 4.32Å
56G94.7Very high94.7Very high1 Ų138.1 Ų38.11%0.0119%0.191CC..SBendtrans-141.1-159.9166.200000111.9D51 N52 F53 L60 Q153 G154D51-G56 VanDerWaalsContact O-CA 3.24Å; D51-G56 WeakPolarHBondContact O-CA 3.33Å; D51-G56 PolarHBondContact O-N 3.31Å; D51-G56 VanDerWaalsContact O-N 3.08Å; N52-G56 CarbonylContact C-O 3.01Å; F53-G56 CarbonylContact C-O 3.54Å; F53-G56 PolarHBondContact N-O 2.87Å; G56-L60 WeakPolarHBondContact CA-O 3.36Å; G56-Q153 CarbonylContact C-O 3.27Å; G56-Q153 WeakPolarHBondContact CA-O 3.24Å; G56-G154 WeakPolarHBondContact O-CA 3.46Å
57N93.4Very high94.6Very high63 Ų6335.6 Ų35.634%0.33718%0.182SC..  trans-136.9179.4173.161.256000110.1N52 D59 L60 P61N52-N57 WeakPolarHBondContact CB-O 3.44Å; N52-N57 CarbonylContact O-C 3.38Å; N52-N57 WeakPolarHBondContact O-CA 3.48Å; N57-D59 VanDerWaalsContact C-N 3.3Å; N57-D59 PolarHBondContact O-N 2.91Å; N57-D59 PolarHBondContact OD1-N 2.9Å; N57-D59 VanDerWaalsContact OD1-N 3.08Å; N57-L60 PolarHBondContact N-O 2.83Å; N57-L60 VanDerWaalsContact N-O 3.07Å; N57-L60 CarbonylContact O-C 3.54Å; N57-L60 VanDerWaalsContact O-C 3.23Å; N57-L60 PolarHBondContact O-N 2.76Å; N57-L60 PolarHBondContact OD1-N 2.88Å; N57-P61 WeakPolarHBondContact O-CA 3.32Å
58D92Very high94.4Very high132 Ų13236.9 Ų36.971%0.70619%0.188SC*.SBendtrans-61.2-34.5-177.1-69-37.6000113.7N52N52-D58 PolarHBondContact ND2-OD1 2.97Å
59D93.8Very high94.3Very high145 Ų14541.1 Ų41.178%0.77521%0.21SC*.SBendtrans-81.5-38.9179.3-59.9-45.8000111.9N57N57-D59 VanDerWaalsContact C-N 3.3Å; N57-D59 PolarHBondContact O-N 2.91Å; N57-D59 PolarHBondContact OD1-N 2.9Å; N57-D59 VanDerWaalsContact OD1-N 3.08Å
60L94.3Very high94.3Very high80 Ų8043.3 Ų43.342%0.41922%0.221SC..SBendtrans-129.579.9-172.1-60.8178.8000108.8G56 N57 R152G56-L60 WeakPolarHBondContact CA-O 3.36Å; N57-L60 PolarHBondContact N-O 2.83Å; N57-L60 VanDerWaalsContact N-O 3.07Å; N57-L60 CarbonylContact O-C 3.54Å; N57-L60 VanDerWaalsContact O-C 3.23Å; N57-L60 PolarHBondContact O-N 2.76Å; N57-L60 PolarHBondContact OD1-N 2.88Å; L60-R152 WeakPolarHBondContact O-CD 3.35Å
61P95.1Very high94.2Very high33 Ų3350.3 Ų50.321%0.21426%0.259CS..  trans-66.7145.1179.126.4-34.2000110.7N57 Q148 R152N57-P61 WeakPolarHBondContact O-CA 3.32Å; P61-Q148 PolarHBondContact O-NE2 3.24Å; P61-R152 WeakPolarHBondContact O-CD 3.3Å; P61-R152 PolarHBondContact O-NE 2.85Å
62G96.6Very high94.3Very high0 Ų056.8 Ų56.80%029%0.293CS..EExtended strand (participates in β ladder)trans-78.4-179165.700000111.5G50 D51 N159G50-G62 VanDerWaalsContact CA-O 3.3Å; G50-G62 WeakPolarHBondContact CA-O 3.16Å; D51-G62 PolarHBondContact N-O 2.91Å; D51-G62 PolarHBondContact O-N 2.91Å; G62-N159 WeakPolarHBondContact CA-OD1 3.26Å
63R97.4Very high94.4Very high14 Ų1455.3 Ų55.35%0.05329%0.287CS..EExtended strand (participates in β ladder)trans-120.7129.4168.7-80.4179.8177.1-93.71.4110.8F47 H49 L137 G138 I149 N159F47-R63 WeakPolarHBondContact O-CD 3.49Å; F47-R63 PolarHBondContact O-NH1 3.36Å; H49-R63 CarbonylContact O-C 3.56Å; H49-R63 WeakPolarHBondContact O-CA 3.47Å; R63-L137 HydrophobicContact CG-CD1 3.78Å; R63-G138 PolarHBondContact NH1-O 2.94Å; R63-I149 HydrophobicContact CB-CD1 4.3Å; R63-I149 HydrophobicContact CB-CG1 4.03Å; R63-N159 PolarHBondContact N-OD1 2.96Å; R63-N159 PolarHBondContact O-ND2 2.87Å; R63-N159 PolarHBondContact O-OD1 3.23Å
64V96Very high94.7Very high6 Ų654 Ų544%0.03629%0.287CS..EExtended strand (participates in β ladder)trans-124.8167174.1-64.20000109.8F47 H49 D51 R55 Y162F47-V64 CarbonylContact C-O 3.5Å; F47-V64 WeakPolarHBondContact CA-O 3.2Å; H49-V64 HydrophobicContact CB-CG2 4.12Å; H49-V64 PolarHBondContact N-O 3.28Å; H49-V64 PolarHBondContact O-N 3.22Å; D51-V64 HydrophobicContact CB-CG1 3.74Å; D51-V64 HydrophobicContact CB-CG2 4.02Å; R55-V64 HydrophobicContact CB-CG1 4.38Å; R55-V64 HydrophobicContact CG-CG1 4.1Å; V64-Y162 HydrophobicContact CB-CE1 4.16Å; V64-Y162 HydrophobicContact CB-CE2 4.17Å; V64-Y162 HydrophobicContact CG1-CD2 4.15Å; V64-Y162 HydrophobicContact CG1-CE1 4.29Å; V64-Y162 HydrophobicContact CG1-CE2 3.87Å; V64-Y162 HydrophobicContact CG1-CG 4.46Å
65V96.8Very high95Very high3 Ų351.6 Ų51.62%0.01828%0.276CS..EExtended strand (participates in β ladder)trans-78.6142.6-179.6-63.20000112.4Y21 G22 R45 R46 F47 Y162 L166Y21-V65 HydrophobicContact CD2-CG2 3.85Å; Y21-V65 HydrophobicContact CE2-CG2 4.07Å; G22-V65 VanDerWaalsContact CA-CG2 3.45Å; R45-V65 HydrophobicContact CG-CB 3.72Å; R45-V65 HydrophobicContact CG-CG1 3.73Å; R45-V65 HydrophobicContact CG-CG2 4.13Å; R46-V65 CarbonylContact O-C 3.51Å; R46-V65 VanDerWaalsContact O-CA 3.26Å; R46-V65 WeakPolarHBondContact O-CA 3.33Å; F47-V65 HydrophobicContact CD1-CG1 4Å; F47-V65 HydrophobicContact CD2-CG1 3.6Å; F47-V65 HydrophobicContact CE1-CG1 3.89Å; F47-V65 HydrophobicContact CE2-CG1 3.46Å; F47-V65 VanDerWaalsContact CE2-CG1 3.46Å; F47-V65 HydrophobicContact CG-CG1 3.87Å; F47-V65 HydrophobicContact CZ-CG1 3.62Å; V65-Y162 HydrophobicContact CG1-CE1 4.44Å; V65-Y162 HydrophobicContact CG2-CE1 4.43Å; V65-Y162 WeakPolarHBondContact CG2-OH 3.43Å; V65-Y162 PolarHBondContact N-OH 3.43Å; V65-L166 HydrophobicContact CG1-CD2 3.71Å; V65-L166 HydrophobicContact CG2-CD2 4.22Å
66T95.1Very high95.2Very high0 Ų052.4 Ų52.40%028%0.279CS..EExtended strand (participates in β ladder)trans-126.7174.6159.9-169.80000109.1R46 H49 I68 A129 F136R46-T66 PolarHBondContact N-O 2.82Å; R46-T66 PolarHBondContact O-N 3.3Å; H49-T66 HydrophobicContact CB-CG2 4.1Å; T66-I68 HydrophobicContact CG2-CD1 4.09Å; T66-A129 PolarHBondContact OG1-N 2.87Å; T66-A129 PolarHBondContact OG1-O 2.84Å; T66-F136 HydrophobicContact CG2-CE2 4.31Å
67L95.4Very high95.3Very high5 Ų552.4 Ų52.43%0.02628%0.279CS..EExtended strand (participates in β ladder)trans-105.3136.6173.4-60.1-176.6000110.6Y21 I40 Y43 K44 R45 T75 L126 I128Y21-L67 HydrophobicContact CD1-CD1 3.73Å; Y21-L67 HydrophobicContact CD1-CD2 4.31Å; Y21-L67 HydrophobicContact CD1-CG 3.98Å; Y21-L67 HydrophobicContact CD2-CD1 4.47Å; Y21-L67 HydrophobicContact CD2-CD2 3.65Å; Y21-L67 HydrophobicContact CD2-CG 3.84Å; Y21-L67 HydrophobicContact CE1-CD1 3.85Å; Y21-L67 HydrophobicContact CE1-CG 3.95Å; Y21-L67 HydrophobicContact CE2-CD2 4.09Å; Y21-L67 HydrophobicContact CE2-CG 3.82Å; Y21-L67 HydrophobicContact CG-CD1 4.05Å; Y21-L67 HydrophobicContact CG-CD2 3.77Å; Y21-L67 HydrophobicContact CG-CG 3.92Å; I40-L67 HydrophobicContact CD1-CD1 3.88Å; Y43-L67 HydrophobicContact CD1-CB 3.91Å; Y43-L67 HydrophobicContact CD1-CD1 4.38Å; Y43-L67 HydrophobicContact CG-CB 4.29Å; Y43-L67 HydrophobicContact CG-CD1 4.14Å; K44-L67 WeakPolarHBondContact O-CA 3.33Å; R45-L67 HydrophobicContact CB-CD2 4.08Å; L67-T75 HydrophobicContact CD2-CG2 3.89Å; L67-L126 HydrophobicContact CD1-CD1 3.58Å; L67-L126 HydrophobicContact CD1-CD2 3.84Å; L67-L126 HydrophobicContact CD1-CG 4.23Å; L67-I128 HydrophobicContact CB-CD1 4.41Å; L67-I128 HydrophobicContact CB-CG2 3.93Å; L67-I128 HydrophobicContact CD1-CD1 4.39Å; L67-I128 HydrophobicContact CD1-CG1 4.37Å; L67-I128 WeakPolarHBondContact O-CG2 3.23Å
68I94.9Very high95.5Very high27 Ų2749.8 Ų49.814%0.13827%0.265CS..EExtended strand (participates in β ladder)trans-113135.5172.8-50.5-61.9000107.4Y43 K44 R46 W48 T66 D70 F136Y43-I68 CarbonylContact C-O 3.58Å; Y43-I68 WeakPolarHBondContact CA-O 3.47Å; K44-I68 HydrophobicContact CD-CB 4.37Å; K44-I68 HydrophobicContact CG-CB 3.79Å; K44-I68 WeakPolarHBondContact CG-O 3.46Å; K44-I68 PolarHBondContact N-O 3.08Å; K44-I68 PolarHBondContact O-N 2.94Å; R46-I68 HydrophobicContact CB-CG1 4.22Å; R46-I68 HydrophobicContact CG-CG1 4.03Å; W48-I68 HydrophobicContact CE3-CD1 3.78Å; W48-I68 HydrophobicContact CE3-CG1 3.65Å; W48-I68 HydrophobicContact CZ3-CD1 4.16Å; W48-I68 HydrophobicContact CZ3-CG1 3.72Å; W48-I68 HydrophobicContact CZ3-CG2 4.45Å; T66-I68 HydrophobicContact CG2-CD1 4.09Å; I68-D70 PolarHBondContact O-N 2.96Å; I68-F136 HydrophobicContact CD1-CE2 3.93Å; I68-F136 HydrophobicContact CD1-CZ 4.2Å
69E93.8Very high95.7Very high128 Ų12843.5 Ų43.560%0.59823%0.232SC*.EExtended strand (participates in β ladder)trans-60.8132.9175.8-69.5177.8-177.800110.5G42 Y43 K107G42-E69 WeakPolarHBondContact O-CA 3.49Å; Y43-E69 HydrophobicContact CD1-CG 4.17Å; Y43-E69 HydrophobicContact CE1-CG 3.66Å; E69-K107 IonicContact OE1-NZ 3.98Å; E69-K107 PolarHBondContact OE1-NZ 3.1Å
70D94.9Very high95.8Very high49 Ų4936.9 Ų36.926%0.26220%0.196SC..EExtended strand (participates in β ladder)trans-165102.2-179.7-167.9-30.5000107.7G42 Y43 K44 I68 D72 A73G42-D70 CarbonylContact C-O 3.01Å; G42-D70 WeakPolarHBondContact CA-O 3.49Å; G42-D70 PolarHBondContact O-N 3.2Å; Y43-D70 PolarHBondContact N-O 2.98Å; K44-D70 HydrophobicContact CB-CB 4.31Å; K44-D70 HydrophobicContact CD-CB 4.02Å; K44-D70 WeakPolarHBondContact CD-OD2 3.3Å; K44-D70 WeakPolarHBondContact CE-OD2 3.38Å; K44-D70 HydrophobicContact CG-CB 4.04Å; K44-D70 IonicContact NZ-OD2 2.59Å; K44-D70 PolarHBondContact NZ-OD2 3.15Å; I68-D70 PolarHBondContact O-N 2.96Å; D70-D72 PolarHBondContact O-N 3.38Å; D70-D72 VanDerWaalsContact O-N 3.16Å; D70-A73 HydrophobicContact CB-CB 3.62Å; D70-A73 WeakPolarHBondContact O-CB 3.47Å; D70-A73 PolarHBondContact O-N 3.45Å
71D93.3Very high95.8Very high148 Ų14834.2 Ų34.279%0.79118%0.181SC*.EExtended strand (participates in β ladder)trans-59.6-28.9-168.7-69.3-23.2000113.2
72D94.3Very high95.6Very high159 Ų15932.7 Ų32.785%0.8517%0.171SC*.EExtended strand (participates in β ladder)trans-90.3-3.8179.7-62.3-43.9000112.7D70D70-D72 PolarHBondContact O-N 3.38Å; D70-D72 VanDerWaalsContact O-N 3.16Å
73A95.8Very high95.2Very high15 Ų1534.4 Ų34.412%0.12418%0.182CC..EExtended strand (participates in β ladder)trans-91.9146.8-175.600000113.1H41 G42 Y43 K44 D70H41-A73 CarbonylContact C-O 3.52Å; H41-A73 WeakPolarHBondContact CA-O 2.89Å; G42-A73 PolarHBondContact N-O 2.87Å; Y43-A73 WeakPolarHBondContact O-CB 3.37Å; K44-A73 HydrophobicContact CB-CB 3.92Å; D70-A73 HydrophobicContact CB-CB 3.62Å; D70-A73 WeakPolarHBondContact O-CB 3.47Å; D70-A73 PolarHBondContact O-N 3.45Å
74T95.8Very high94.5Very high61 Ų6136 Ų3637%0.37420%0.202SC..EExtended strand (participates in β ladder)trans-119.4132.5172.8-63.60000109.1Y39 I40 H41Y39-T74 HydrophobicContact CD2-CG2 3.39Å; Y39-T74 HydrophobicContact CE2-CG2 4.23Å; Y39-T74 HydrophobicContact CG-CG2 3.58Å; I40-T74 WeakPolarHBondContact O-CA 3.26Å; H41-T74 PolarHBondContact ND1-OG1 3.46Å
75T97.7Very high93.6Very high4 Ų439.9 Ų39.93%0.02523%0.23CC..EExtended strand (participates in β ladder)trans-116.3121.6174-69.70000110.6Y39 I40 Y43 R45 L67Y39-T75 VanDerWaalsContact CA-O 3.25Å; Y39-T75 WeakPolarHBondContact CA-O 3.11Å; Y39-T75 WeakPolarHBondContact CB-O 3.05Å; I40-T75 PolarHBondContact N-O 3.16Å; I40-T75 PolarHBondContact O-N 2.78Å; Y43-T75 PolarHBondContact O-OG1 2.87Å; R45-T75 HydrophobicContact CB-CG2 4.1Å; R45-T75 PolarHBondContact N-OG1 2.86Å; L67-T75 HydrophobicContact CD2-CG2 3.89Å
76W97.9Very high92.8Very high28 Ų2841.7 Ų41.711%0.10624%0.238CC..EExtended strand (participates in β ladder)trans-87143.4176.3-75.176.4000112.5V37 G38 Y39 R45 E114 M170 C174 H176 V177V37-W76 HydrophobicContact CG1-CE3 4.2Å; V37-W76 HydrophobicContact CG1-CZ3 4.34Å; G38-W76 WeakPolarHBondContact O-CA 3.2Å; Y39-W76 HydrophobicContact CD1-CD2 4.16Å; Y39-W76 AromaticContact CD1-CE2 3.63Å; Y39-W76 HydrophobicContact CD1-CE3 4.4Å; Y39-W76 AromaticContact CD1-CH2 3.69Å; Y39-W76 HydrophobicContact CD1-CH2 3.69Å; Y39-W76 AromaticContact CD1-CZ2 3.37Å; Y39-W76 HydrophobicContact CD1-CZ2 3.37Å; Y39-W76 HydrophobicContact CD1-CZ3 4.2Å; Y39-W76 HydrophobicContact CE1-CH2 4.13Å; Y39-W76 AromaticContact CE1-CZ2 3.87Å; Y39-W76 HydrophobicContact CE1-CZ2 3.87Å; Y39-W76 HydrophobicContact CG-CD2 4.44Å; Y39-W76 HydrophobicContact CG-CZ2 4.22Å; R45-W76 PolarHBondContact NH1-O 2.91Å; W76-E114 HydrophobicContact CH2-CB 4.18Å; W76-E114 HydrophobicContact CH2-CG 3.95Å; W76-E114 HydrophobicContact CZ3-CB 3.84Å; W76-E114 HydrophobicContact CZ3-CG 3.87Å; W76-M170 HydrophobicContact CB-CE 4.19Å; W76-M170 HydrophobicContact CB-SD 4.41Å; W76-C174 HydrophobicContact CE3-CB 4.37Å; W76-H176 AromaticContact CE2-NE2 3.95Å; W76-H176 AromaticContact CH2-CE1 3.5Å; W76-H176 VanDerWaalsContact CH2-CE1 3.5Å; W76-H176 WeakPolarHBondContact CH2-CE1 3.41Å; W76-H176 AromaticContact CH2-NE2 3.05Å; W76-H176 WeakPolarHBondContact CH2-NE2 3.3Å; W76-H176 AromaticContact CZ2-NE2 3.2Å; W76-H176 WeakPolarHBondContact CZ2-NE2 3.27Å; W76-H176 AromaticContact CZ3-CE1 3.75Å; W76-H176 AromaticContact CZ3-NE2 3.73Å; W76-V177 VanDerWaalsContact CD1-CG1 3.46Å; W76-V177 HydrophobicContact CD2-CG2 3.53Å; W76-V177 HydrophobicContact CE3-CG2 4.19Å; W76-V177 HydrophobicContact CG-CB 4.4Å; W76-V177 HydrophobicContact CG-CG1 4Å; W76-V177 HydrophobicContact CG-CG2 3.68Å; W76-V177 HydrophobicContact CZ2-CG2 3.92Å
77G97.6Very high92Very high0 Ų042 Ų420%024%0.24CC..EExtended strand (participates in β ladder)trans-170.5-156.1-175.400000112.3G20 V37 G38G20-G77 VanDerWaalsContact O-CA 3.23Å; G20-G77 WeakPolarHBondContact O-CA 3.5Å; V37-G77 WeakPolarHBondContact CA-O 3.49Å; G38-G77 PolarHBondContact N-O 2.97Å; G38-G77 VanDerWaalsContact N-O 3.16Å; G38-G77 PolarHBondContact O-N 2.87Å
78V97.5Very high91.1Very high9 Ų949.2 Ų49.26%0.05527%0.274CS..EExtended strand (participates in β ladder)trans-127.6129.5179.4-174.70000109.3G20 V25 Q36 V37 F80 F169G20-V78 PolarHBondContact N-O 2.77Å; G20-V78 PolarHBondContact O-N 2.84Å; V25-V78 HydrophobicContact CB-CG2 4.07Å; V25-V78 HydrophobicContact CG1-CG2 4.14Å; Q36-V78 CarbonylContact O-C 3.53Å; Q36-V78 WeakPolarHBondContact O-CA 3.22Å; V37-V78 HydrophobicContact CG2-CG2 4.36Å; V78-F80 HydrophobicContact CB-CE2 3.79Å; V78-F80 HydrophobicContact CB-CZ 3.82Å; V78-F80 HydrophobicContact CG1-CD1 4.32Å; V78-F80 HydrophobicContact CG1-CD2 4.26Å; V78-F80 HydrophobicContact CG1-CE1 3.78Å; V78-F80 HydrophobicContact CG1-CE2 3.71Å; V78-F80 HydrophobicContact CG1-CZ 3.44Å; V78-F80 VanDerWaalsContact CG1-CZ 3.44Å; V78-F169 HydrophobicContact CG2-CD2 4.44Å; V78-F169 HydrophobicContact CG2-CE2 3.41Å; V78-F169 VanDerWaalsContact CG2-CE2 3.41Å; V78-F169 HydrophobicContact CG2-CZ 3.6Å
79A96.6Very high90.3Very high0 Ų053.3 Ų53.30%029%0.293CS..EExtended strand (participates in β ladder)trans-95.3136.2167.700000110.1W17 I18 F19 S35 Q36 F111W17-A79 HydrophobicContact CE3-CB 3.63Å; W17-A79 HydrophobicContact CZ3-CB 4.19Å; I18-A79 CarbonylContact O-C 3.23Å; I18-A79 WeakPolarHBondContact O-CA 3.43Å; F19-A79 HydrophobicContact CD2-CB 4.43Å; S35-A79 CarbonylContact C-O 3.53Å; S35-A79 WeakPolarHBondContact CA-O 3.23Å; Q36-A79 PolarHBondContact N-O 2.86Å; Q36-A79 PolarHBondContact O-N 3.47Å; A79-F111 HydrophobicContact CB-CD1 3.53Å; A79-F111 HydrophobicContact CB-CD2 3.91Å; A79-F111 HydrophobicContact CB-CE1 3.4Å; A79-F111 HydrophobicContact CB-CE2 3.77Å; A79-F111 HydrophobicContact CB-CG 3.78Å; A79-F111 HydrophobicContact CB-CZ 3.52Å
80F95.1Very high89.5Confident5 Ų547.3 Ų47.32%0.02227%0.265CS..EExtended strand (participates in β ladder)trans-115.9121.3179.5-59.6-88.5000110.5W17 I18 L24 P28 F30 Y32 V78W17-F80 CarbonylContact C-O 3.55Å; W17-F80 VanDerWaalsContact CA-O 3.32Å; W17-F80 WeakPolarHBondContact CA-O 3.35Å; I18-F80 PolarHBondContact N-O 2.9Å; I18-F80 PolarHBondContact O-N 2.86Å; L24-F80 HydrophobicContact CB-CE2 4.31Å; L24-F80 VanDerWaalsContact O-CZ 3.26Å; L24-F80 WeakPolarHBondContact O-CZ 3.38Å; P28-F80 HydrophobicContact CB-CD1 4.48Å; P28-F80 HydrophobicContact CB-CE1 4.09Å; P28-F80 HydrophobicContact CB-CE2 4.49Å; P28-F80 HydrophobicContact CB-CZ 4.09Å; P28-F80 HydrophobicContact CG-CE1 4.15Å; P28-F80 HydrophobicContact CG-CZ 4.37Å; F30-F80 HydrophobicContact CE2-CB 3.79Å; F30-F80 HydrophobicContact CE2-CG 4.19Å; F30-F80 HydrophobicContact CZ-CB 3.95Å; F30-F80 HydrophobicContact CZ-CD2 4.1Å; F30-F80 HydrophobicContact CZ-CG 4.02Å; Y32-F80 AromaticContact CD1-CD1 3.73Å; Y32-F80 HydrophobicContact CD1-CD1 3.73Å; Y32-F80 HydrophobicContact CD1-CE1 4.35Å; Y32-F80 AromaticContact CD2-CD1 3.96Å; Y32-F80 HydrophobicContact CD2-CD1 3.96Å; Y32-F80 AromaticContact CE1-CD1 3.78Å; Y32-F80 HydrophobicContact CE1-CD1 3.78Å; Y32-F80 AromaticContact CE1-CE1 3.97Å; Y32-F80 HydrophobicContact CE1-CE1 3.97Å; Y32-F80 AromaticContact CE2-CD1 3.99Å; Y32-F80 HydrophobicContact CE2-CD1 3.99Å; Y32-F80 HydrophobicContact CE2-CE1 4.42Å; Y32-F80 HydrophobicContact CG-CB 4.29Å; Y32-F80 AromaticContact CG-CD1 3.82Å; Y32-F80 HydrophobicContact CG-CD1 3.82Å; Y32-F80 AromaticContact CZ-CD1 3.91Å; Y32-F80 AromaticContact CZ-CE1 3.99Å; V78-F80 HydrophobicContact CB-CE2 3.79Å; V78-F80 HydrophobicContact CB-CZ 3.82Å; V78-F80 HydrophobicContact CG1-CD1 4.32Å; V78-F80 HydrophobicContact CG1-CD2 4.26Å; V78-F80 HydrophobicContact CG1-CE1 3.78Å; V78-F80 HydrophobicContact CG1-CE2 3.71Å; V78-F80 HydrophobicContact CG1-CZ 3.44Å; V78-F80 VanDerWaalsContact CG1-CZ 3.44Å
81E93.7Very high88.7Confident25 Ų2545.6 Ų45.612%0.11726%0.255CS..EExtended strand (participates in β ladder)trans-81.1118.2175.9-166.1-168.1-176.400110S15 W17 Y32 K33 S34 T83S15-E81 WeakPolarHBondContact OG-CG 3.33Å; S15-E81 PolarHBondContact OG-OE1 3.12Å; W17-E81 HydrophobicContact CD2-CB 3.92Å; W17-E81 HydrophobicContact CD2-CG 4.3Å; W17-E81 HydrophobicContact CE3-CB 3.88Å; W17-E81 HydrophobicContact CH2-CB 3.69Å; W17-E81 HydrophobicContact CH2-CG 4.4Å; W17-E81 HydrophobicContact CZ2-CB 3.69Å; W17-E81 HydrophobicContact CZ2-CG 3.9Å; W17-E81 HydrophobicContact CZ3-CB 3.78Å; Y32-E81 CarbonylContact C-O 3.54Å; Y32-E81 WeakPolarHBondContact CA-O 3.38Å; Y32-E81 WeakPolarHBondContact CB-O 3.5Å; K33-E81 WeakPolarHBondContact CD-OE2 3.44Å; K33-E81 WeakPolarHBondContact CE-OE2 3.27Å; K33-E81 PolarHBondContact N-O 2.83Å; K33-E81 IonicContact NZ-OE1 2.61Å; K33-E81 PolarHBondContact NZ-OE1 2.72Å; K33-E81 IonicContact NZ-OE2 3.36Å; K33-E81 PolarHBondContact NZ-OE2 3.5Å; S34-E81 PolarHBondContact O-N 2.93Å; S34-E81 VanDerWaalsContact OG-CB 3.25Å; S34-E81 WeakPolarHBondContact OG-CB 3.3Å; S34-E81 PolarHBondContact OG-OE2 2.66Å; E81-T83 HydrophobicContact CG-CG2 4.19Å
82V91Very high87.8Confident0 Ų046 Ų460%025%0.25CC..EExtended strand (participates in β ladder)trans-112.2138.4172.3-62.90000109.6S15 L16 I18 F30 Q86 V87S15-V82 CarbonylContact C-O 3.31Å; S15-V82 WeakPolarHBondContact CA-O 3.27Å; L16-V82 HydrophobicContact CB-CG2 3.98Å; L16-V82 HydrophobicContact CG-CG2 4.49Å; L16-V82 PolarHBondContact N-O 3.37Å; L16-V82 VanDerWaalsContact O-CG2 3.26Å; L16-V82 WeakPolarHBondContact O-CG2 3.4Å; L16-V82 PolarHBondContact O-N 2.93Å; I18-V82 HydrophobicContact CD1-CG1 4.12Å; I18-V82 HydrophobicContact CD1-CG2 3.85Å; I18-V82 HydrophobicContact CG1-CG2 4.45Å; F30-V82 HydrophobicContact CD2-CG1 3.9Å; F30-V82 HydrophobicContact CE2-CG1 3.83Å; V82-Q86 HydrophobicContact CB-CB 4.16Å; V82-V87 HydrophobicContact CG2-CG2 4.06Å; V82-V87 WeakPolarHBondContact O-CG2 3.37Å
83T88Confident86.9Confident36 Ų3642.1 Ų42.122%0.22122%0.224CC..EExtended strand (participates in β ladder)trans-131.9152.6-172.960.10000113.1T14 K33 E81 S85 Q86T14-T83 VanDerWaalsContact O-CA 3.3Å; T14-T83 WeakPolarHBondContact O-CA 3.18Å; T14-T83 WeakPolarHBondContact O-CB 3.36Å; K33-T83 HydrophobicContact CB-CG2 4.34Å; K33-T83 HydrophobicContact CD-CG2 3.69Å; E81-T83 HydrophobicContact CG-CG2 4.19Å; T83-S85 PolarHBondContact O-N 2.76Å; T83-Q86 WeakPolarHBondContact O-CB 3.25Å; T83-Q86 WeakPolarHBondContact O-CG 3.32Å; T83-Q86 PolarHBondContact O-N 2.85Å; T83-Q86 PolarHBondContact O-OE1 2.68Å; T83-Q86 PolarHBondContact OG1-OE1 2.72Å
84G83.3Confident85.8Confident47 Ų4741.5 Ų41.549%0.48522%0.218SC..THydrogen-bonded Turntrans52.5-127.5176.800000113T14 Q86 V87T14-G84 PolarHBondContact O-N 3.07Å; T14-G84 VanDerWaalsContact O-N 3.1Å; G84-Q86 PolarHBondContact O-N 3.08Å; G84-V87 WeakPolarHBondContact O-CB 3.12Å; G84-V87 WeakPolarHBondContact O-CG2 3.42Å; G84-V87 PolarHBondContact O-N 3.36Å
85S78.3Confident84.6Confident89 Ų8940.3 Ų40.362%0.62221%0.21SC*.Hα-helixtrans-64.6-19.3-179.960.60000114.2T83 V87 E89T83-S85 PolarHBondContact O-N 2.76Å; S85-V87 PolarHBondContact O-N 3.23Å; S85-E89 PolarHBondContact O-N 3.31Å
86Q77.9Confident83.1Confident40 Ų4044.3 Ų44.319%0.18723%0.234CC..Hα-helixtrans-67.1-27.4177.9-57.4170.9-28.800112.1K31 V82 T83 G84 S90K31-Q86 HydrophobicContact CB-CG 4.48Å; V82-Q86 HydrophobicContact CB-CB 4.16Å; T83-Q86 WeakPolarHBondContact O-CB 3.25Å; T83-Q86 WeakPolarHBondContact O-CG 3.32Å; T83-Q86 PolarHBondContact O-N 2.85Å; T83-Q86 PolarHBondContact O-OE1 2.68Å; T83-Q86 PolarHBondContact OG1-OE1 2.72Å; G84-Q86 PolarHBondContact O-N 3.08Å; Q86-S90 WeakPolarHBondContact O-CB 3.11Å; Q86-S90 PolarHBondContact O-N 3.08Å; Q86-S90 PolarHBondContact O-OG 2.91Å
87V78.5Confident81.5Confident7 Ų745.4 Ų45.44%0.04224%0.238CC..Hα-helixtrans-60.8-54.1-179.8177.90000109.2L16 V82 G84 S85 E89 S90 L91L16-V87 HydrophobicContact CB-CG1 4.37Å; L16-V87 HydrophobicContact CB-CG2 4.41Å; L16-V87 HydrophobicContact CD2-CG1 4.23Å; V82-V87 HydrophobicContact CG2-CG2 4.06Å; V82-V87 WeakPolarHBondContact O-CG2 3.37Å; G84-V87 WeakPolarHBondContact O-CB 3.12Å; G84-V87 WeakPolarHBondContact O-CG2 3.42Å; G84-V87 PolarHBondContact O-N 3.36Å; S85-V87 PolarHBondContact O-N 3.23Å; V87-E89 PolarHBondContact O-N 3.45Å; V87-S90 PolarHBondContact O-N 2.91Å; V87-L91 HydrophobicContact CG1-CD1 3.6Å; V87-L91 HydrophobicContact CG1-CG 4.46Å; V87-L91 WeakPolarHBondContact O-CB 3.24Å; V87-L91 VanDerWaalsContact O-CD1 3.26Å; V87-L91 WeakPolarHBondContact O-CD1 2.95Å; V87-L91 WeakPolarHBondContact O-CG 3.37Å; V87-L91 PolarHBondContact O-N 3.22Å
88E77.3Confident79.8Confident156 Ų15646.9 Ų46.973%0.72925%0.245SC*.Hα-helixtrans-63.9-41.6-179-66.2-172.3178.300112.6K92E88-K92 WeakPolarHBondContact O-CB 3.17Å; E88-K92 PolarHBondContact O-N 3.3Å
89E78.8Confident77.6Confident114 Ų11450.4 Ų50.453%0.53328%0.276SS..Hα-helixtrans-62.2-48.2177.4-71179.4-179.400111.8S85 V87 K92 Y93S85-E89 PolarHBondContact O-N 3.31Å; V87-E89 PolarHBondContact O-N 3.45Å; E89-K92 PolarHBondContact O-N 2.78Å; E89-Y93 WeakPolarHBondContact O-CB 2.96Å; E89-Y93 PolarHBondContact O-N 3.33Å
90S76.7Confident75.5Confident2 Ų256 Ų561%0.01431%0.309CS..Hα-helixtrans-65.8-43.3-178.8-56.10000111Q86 V87 Y93 L94Q86-S90 WeakPolarHBondContact O-CB 3.11Å; Q86-S90 PolarHBondContact O-N 3.08Å; Q86-S90 PolarHBondContact O-OG 2.91Å; V87-S90 PolarHBondContact O-N 2.91Å; S90-Y93 PolarHBondContact O-N 3.31Å; S90-L94 WeakPolarHBondContact O-CB 3.35Å; S90-L94 VanDerWaalsContact O-CG 3.24Å; S90-L94 WeakPolarHBondContact O-CG 3.23Å; S90-L94 PolarHBondContact O-N 3.01Å
91L77.2Confident73.4Confident12 Ų1257.8 Ų57.86%0.06332%0.322CS..Hα-helixtrans-65.9-38.9175.8-68.5164.8000112P3 I7 L16 V87 N95 L125P3-L91 HydrophobicContact CB-CD2 4.28Å; I7-L91 HydrophobicContact CD1-CD1 3.07Å; I7-L91 HydrophobicContact CD1-CD2 4.15Å; I7-L91 HydrophobicContact CD1-CG 4.21Å; I7-L91 HydrophobicContact CG1-CD1 4.41Å; L16-L91 HydrophobicContact CD2-CD1 4.39Å; L16-L91 HydrophobicContact CD2-CD2 4.02Å; L16-L91 HydrophobicContact CD2-CG 4.4Å; V87-L91 HydrophobicContact CG1-CD1 3.6Å; V87-L91 HydrophobicContact CG1-CG 4.46Å; V87-L91 WeakPolarHBondContact O-CB 3.24Å; V87-L91 VanDerWaalsContact O-CD1 3.26Å; V87-L91 WeakPolarHBondContact O-CD1 2.95Å; V87-L91 WeakPolarHBondContact O-CG 3.37Å; V87-L91 PolarHBondContact O-N 3.22Å; L91-N95 WeakPolarHBondContact O-CB 3.24Å; L91-N95 PolarHBondContact O-N 2.81Å; L91-N95 PolarHBondContact O-ND2 3.3Å; L91-L125 HydrophobicContact CD2-CD2 3.43Å; L91-L125 VanDerWaalsContact CD2-CD2 3.43Å
92K75.9Confident71.5Confident156 Ų15657.9 Ų57.968%0.67833%0.33SS*.Hα-helixtrans-63.7-45175.5-173.7178.6-179.7-177.50110.5E88 E89 N95 V96E88-K92 WeakPolarHBondContact O-CB 3.17Å; E88-K92 PolarHBondContact O-N 3.3Å; E89-K92 PolarHBondContact O-N 2.78Å; K92-N95 PolarHBondContact O-N 3.41Å; K92-V96 VanDerWaalsContact O-CG2 3.31Å; K92-V96 WeakPolarHBondContact O-CG2 3.33Å; K92-V96 PolarHBondContact O-N 2.93Å
93Y73.8Confident70.2Confident78 Ų7859.8 Ų59.831%0.30635%0.35SS..Hα-helixtrans-60.1-52175.8170.7-99.7000111.9D29 F30 E89 S90 N95 V96 R97D29-Y93 HydrophobicContact CB-CE1 4.2Å; D29-Y93 VanDerWaalsContact CB-OH 3.32Å; D29-Y93 WeakPolarHBondContact CB-OH 3.21Å; F30-Y93 HydrophobicContact CD1-CD1 4.4Å; E89-Y93 WeakPolarHBondContact O-CB 2.96Å; E89-Y93 PolarHBondContact O-N 3.33Å; S90-Y93 PolarHBondContact O-N 3.31Å; Y93-N95 VanDerWaalsContact C-N 3.31Å; Y93-N95 PolarHBondContact O-N 2.94Å; Y93-V96 PolarHBondContact O-N 2.86Å; Y93-V96 VanDerWaalsContact O-N 3.16Å; Y93-R97 WeakPolarHBondContact O-CB 3.34Å; Y93-R97 PolarHBondContact O-N 3.34Å; Y93-R97 PolarHBondContact OH-NH1 2.95Å
94L72.5Confident69.5Low2 Ų260.7 Ų60.71%0.0135%0.349CS..Hα-helixtrans-63.7-37.8178.9-67.9171000111.3I18 L24 F30 S90 V96 R97 E98 Y127I18-L94 HydrophobicContact CD1-CD1 3.8Å; I18-L94 HydrophobicContact CG1-CD1 4.44Å; I18-L94 HydrophobicContact CG2-CD1 3.9Å; L24-L94 HydrophobicContact CD2-CD2 4.41Å; F30-L94 HydrophobicContact CE1-CD1 4.5Å; F30-L94 HydrophobicContact CE1-CD2 4.48Å; S90-L94 WeakPolarHBondContact O-CB 3.35Å; S90-L94 VanDerWaalsContact O-CG 3.24Å; S90-L94 WeakPolarHBondContact O-CG 3.23Å; S90-L94 PolarHBondContact O-N 3.01Å; L94-V96 PolarHBondContact O-N 3.48Å; L94-R97 PolarHBondContact O-N 2.92Å; L94-E98 WeakPolarHBondContact O-CB 2.95Å; L94-E98 VanDerWaalsContact O-CG 3.23Å; L94-E98 WeakPolarHBondContact O-CG 3.4Å; L94-E98 PolarHBondContact O-N 3.43Å; L94-Y127 HydrophobicContact CB-CE1 4.03Å; L94-Y127 HydrophobicContact CB-CE2 4.07Å; L94-Y127 HydrophobicContact CD1-CD2 4.36Å; L94-Y127 HydrophobicContact CD1-CE2 3.66Å; L94-Y127 HydrophobicContact CG-CE2 4.42Å
95N71.5Confident69.4Low37 Ų3761.2 Ų61.220%0.19834%0.34CS..Hα-helixtrans-65.7-37.7174.4-73.3-27.1000112.7P3 L91 K92 Y93 A99P3-N95 WeakPolarHBondContact CG-OD1 3.46Å; L91-N95 WeakPolarHBondContact O-CB 3.24Å; L91-N95 PolarHBondContact O-N 2.81Å; L91-N95 PolarHBondContact O-ND2 3.3Å; K92-N95 PolarHBondContact O-N 3.41Å; Y93-N95 VanDerWaalsContact C-N 3.31Å; Y93-N95 PolarHBondContact O-N 2.94Å; N95-A99 WeakPolarHBondContact O-CA 3.37Å; N95-A99 WeakPolarHBondContact O-CB 3.22Å; N95-A99 PolarHBondContact O-N 3.42Å
96V66Low69.7Low88 Ų8857.4 Ų57.453%0.53331%0.314SS..Hα-helixtrans-67.9-43.1175.3169.90000110.3K92 Y93 L94 E98 V100K92-V96 VanDerWaalsContact O-CG2 3.31Å; K92-V96 WeakPolarHBondContact O-CG2 3.33Å; K92-V96 PolarHBondContact O-N 2.93Å; Y93-V96 PolarHBondContact O-N 2.86Å; Y93-V96 VanDerWaalsContact O-N 3.16Å; L94-V96 PolarHBondContact O-N 3.48Å; V96-E98 VanDerWaalsContact C-N 3.26Å; V96-E98 PolarHBondContact O-N 3.41Å; V96-V100 HydrophobicContact CG1-CG2 4.38Å; V96-V100 WeakPolarHBondContact O-CB 3.37Å; V96-V100 VanDerWaalsContact O-CG2 3.27Å; V96-V100 WeakPolarHBondContact O-CG2 3.2Å; V96-V100 PolarHBondContact O-N 2.84Å
97R63.5Low70.2Confident50 Ų5058.2 Ų58.219%0.18932%0.316CS..Hα-helixtrans-60.4-36.7178.8-168.8171.6175.6174.6-6.9112.3S23 Y93 L94S23-R97 PolarHBondContact OG-NH2 2.88Å; Y93-R97 WeakPolarHBondContact O-CB 3.34Å; Y93-R97 PolarHBondContact O-N 3.34Å; Y93-R97 PolarHBondContact OH-NH1 2.95Å; L94-R97 PolarHBondContact O-N 2.92Å
98E61.9Low70.8Confident31 Ų3160.8 Ų60.815%0.14533%0.329CS..Hα-helixtrans-103.4-28.3-173.2-57.6-53.8157.400114.6L94 V96 G102 Y104 Y127L94-E98 WeakPolarHBondContact O-CB 2.95Å; L94-E98 VanDerWaalsContact O-CG 3.23Å; L94-E98 WeakPolarHBondContact O-CG 3.4Å; L94-E98 PolarHBondContact O-N 3.43Å; V96-E98 VanDerWaalsContact C-N 3.26Å; V96-E98 PolarHBondContact O-N 3.41Å; E98-G102 PolarHBondContact O-N 3.46Å; E98-Y104 HydrophobicContact CB-CD2 4.32Å; E98-Y104 HydrophobicContact CB-CG 4.14Å; E98-Y104 HydrophobicContact CG-CD1 4.37Å; E98-Y104 HydrophobicContact CG-CG 4.23Å; E98-Y104 WeakPolarHBondContact OE2-CD1 3.11Å; E98-Y104 WeakPolarHBondContact OE2-CD2 3.31Å; E98-Y104 WeakPolarHBondContact OE2-CE1 3.2Å; E98-Y104 WeakPolarHBondContact OE2-CE2 3.42Å; E98-Y127 HydrophobicContact CB-CD1 4.4Å; E98-Y127 HydrophobicContact CG-CD1 3.87Å; E98-Y127 HydrophobicContact CG-CE1 4.43Å
99A53.3Low71.6Confident84 Ų8454 Ų5469%0.69430%0.299SS*.Hα-helixtrans-80.2-23.5177.100000113.2N95N95-A99 WeakPolarHBondContact O-CA 3.37Å; N95-A99 WeakPolarHBondContact O-CB 3.22Å; N95-A99 PolarHBondContact O-N 3.42Å
100V50.8Low72.4Confident116 Ų11652.5 Ų52.570%0.70330%0.295SS*.SBendtrans-85.8-22.5175.7-178.50000111.4V96V96-V100 HydrophobicContact CG1-CG2 4.38Å; V96-V100 WeakPolarHBondContact O-CB 3.37Å; V96-V100 VanDerWaalsContact O-CG2 3.27Å; V96-V100 WeakPolarHBondContact O-CG2 3.2Å; V96-V100 PolarHBondContact O-N 2.84Å
101C51Low73.3Confident43 Ų4352.4 Ų52.429%0.29129%0.294SS..SBendtrans-111.19.1-174.9-67.70000115.4
102G53.9Low74.2Confident27 Ų2752.6 Ų52.628%0.27830%0.295SS..SBendtrans96.7125.2160.800000115E98 Y104 N133E98-G102 PolarHBondContact O-N 3.46Å; G102-Y104 WeakPolarHBondContact O-CD2 3.34Å; G102-Y104 PolarHBondContact O-N 3.05Å; G102-N133 PolarHBondContact O-ND2 2.88Å
103G63.6Low75.1Confident41 Ų4145.5 Ų45.542%0.42327%0.265SS..  trans76.15.5148.400000119.7
104Y73.8Confident75.9Confident55 Ų5545.3 Ų45.322%0.21627%0.266CS..EExtended strand (participates in β ladder)trans-74.8137.8177-73.5-114.8000111.9E98 G102 I128 A129E98-Y104 HydrophobicContact CB-CD2 4.32Å; E98-Y104 HydrophobicContact CB-CG 4.14Å; E98-Y104 HydrophobicContact CG-CD1 4.37Å; E98-Y104 HydrophobicContact CG-CG 4.23Å; E98-Y104 WeakPolarHBondContact OE2-CD1 3.11Å; E98-Y104 WeakPolarHBondContact OE2-CD2 3.31Å; E98-Y104 WeakPolarHBondContact OE2-CE1 3.2Å; E98-Y104 WeakPolarHBondContact OE2-CE2 3.42Å; G102-Y104 WeakPolarHBondContact O-CD2 3.34Å; G102-Y104 PolarHBondContact O-N 3.05Å; Y104-I128 CarbonylContact C-O 3.55Å; Y104-I128 VanDerWaalsContact CA-O 3.23Å; Y104-I128 WeakPolarHBondContact CA-O 3.37Å; Y104-A129 HydrophobicContact CD1-CB 4.06Å; Y104-A129 HydrophobicContact CD2-CB 3.98Å; Y104-A129 HydrophobicContact CE1-CB 3.76Å; Y104-A129 HydrophobicContact CE2-CB 3.67Å; Y104-A129 HydrophobicContact CG-CB 4.17Å
105I81Confident76.2Confident57 Ų5752.4 Ų52.429%0.29231%0.305SS..EExtended strand (participates in β ladder)trans-102.8154167.866.1170.5000110K107 Y127 I128 T130I105-K107 HydrophobicContact CD1-CD 4.49Å; I105-K107 HydrophobicContact CD1-CG 4.36Å; I105-Y127 WeakPolarHBondContact O-CA 3.18Å; I105-I128 HydrophobicContact CG1-CB 4.25Å; I105-I128 PolarHBondContact N-O 3.37Å; I105-I128 PolarHBondContact O-N 3.21Å; I105-T130 HydrophobicContact CB-CG2 4.27Å; I105-T130 HydrophobicContact CD1-CG2 3.57Å; I105-T130 HydrophobicContact CG1-CG2 3.65Å; I105-T130 HydrophobicContact CG2-CG2 3.7Å
106T84.8Confident76Confident10 Ų1052.5 Ų52.56%0.06131%0.305CS..EExtended strand (participates in β ladder)trans-107.2135171550000111.5M1 P3 I6 L125 L126 Y127M1-T106 PolarHBondContact O-OG1 3.15Å; P3-T106 HydrophobicContact CB-CG2 4Å; P3-T106 HydrophobicContact CG-CG2 3.79Å; I6-T106 WeakPolarHBondContact CD1-OG1 3.47Å; T106-L125 HydrophobicContact CG2-CD1 4.48Å; T106-L126 CarbonylContact C-O 3.55Å; T106-L126 VanDerWaalsContact CA-O 3.24Å; T106-L126 WeakPolarHBondContact CA-O 3.26Å; T106-Y127 HydrophobicContact CG2-CD1 3.53Å; T106-Y127 HydrophobicContact CG2-CD2 4.37Å; T106-Y127 HydrophobicContact CG2-CE1 3.38Å; T106-Y127 HydrophobicContact CG2-CE2 4.24Å; T106-Y127 HydrophobicContact CG2-CG 4.04Å
107K88.9Confident75.6Confident56 Ų5658 Ų5824%0.24333%0.325CS..EExtended strand (participates in β ladder)trans-127.4150.3172.7-66.2-170.8178.7-169.50110.2Y43 E69 I105 V109 L126 I128Y43-K107 WeakPolarHBondContact OH-CD 3.45Å; Y43-K107 PolarHBondContact OH-NZ 3.46Å; E69-K107 IonicContact OE1-NZ 3.98Å; E69-K107 PolarHBondContact OE1-NZ 3.1Å; I105-K107 HydrophobicContact CD1-CD 4.49Å; I105-K107 HydrophobicContact CD1-CG 4.36Å; K107-V109 HydrophobicContact CB-CG1 4.39Å; K107-L126 PolarHBondContact N-O 3.1Å; K107-L126 PolarHBondContact O-N 2.67Å; K107-I128 HydrophobicContact CD-CD1 4.26Å
108L91.4Very high75.6Confident61 Ų6159 Ų5932%0.31934%0.339SS..EExtended strand (participates in β ladder)trans-92.1132.1162.3-71.9175.7000108I6 A124 L125I6-L108 HydrophobicContact CG2-CD1 3.58Å; I6-L108 HydrophobicContact CG2-CD2 4.19Å; I6-L108 HydrophobicContact CG2-CG 3.76Å; L108-A124 WeakPolarHBondContact CA-O 3.18Å; L108-L125 HydrophobicContact CD2-CB 4.35Å; L108-L125 HydrophobicContact CD2-CD1 4.13Å
109V93.9Very high75.6Confident15 Ų1563 Ų639%0.09136%0.362CS..EExtended strand (participates in β ladder)trans-131.9154-179.4-64.30000109.9I40 Y43 K107 F111 A124 L126I40-V109 HydrophobicContact CB-CG2 4.42Å; I40-V109 HydrophobicContact CD1-CG2 4.45Å; I40-V109 HydrophobicContact CG2-CG2 3.76Å; Y43-V109 HydrophobicContact CE2-CG1 3.99Å; K107-V109 HydrophobicContact CB-CG1 4.39Å; V109-F111 PolarHBondContact O-N 3.03Å; V109-A124 PolarHBondContact N-O 3.2Å; V109-A124 PolarHBondContact O-N 3.19Å; V109-L126 HydrophobicContact CG1-CB 4.32Å; V109-L126 HydrophobicContact CG1-CD2 3.69Å; V109-L126 HydrophobicContact CG2-CB 3.91Å; V109-L126 HydrophobicContact CG2-CD2 4.12Å
110D94.8Very high76.8Confident82 Ų8265.4 Ų65.444%0.43936%0.359SS..EExtended strand (participates in β ladder)trans-77116.7170.2-65.9-43.2000109.1T121 Q123D110-T121 HydrophobicContact CB-CG2 4.18Å; D110-Q123 PolarHBondContact OD1-NE2 3.1Å
111F95.8Very high78.6Confident0 Ų063.7 Ų63.70%035%0.349CS..EExtended strand (participates in β ladder)trans-96.9132171.3168.1-104.9000109.3F19 Q36 G38 Y39 I40 A79 V109 P113 T121 Q122 A124F19-F111 AromaticContact CD2-CD2 3.56Å; F19-F111 HydrophobicContact CD2-CD2 3.56Å; F19-F111 AromaticContact CD2-CE2 3.96Å; F19-F111 HydrophobicContact CD2-CE2 3.96Å; F19-F111 HydrophobicContact CD2-CG 4.45Å; F19-F111 AromaticContact CE2-CD2 3.64Å; F19-F111 HydrophobicContact CE2-CD2 3.64Å; F19-F111 AromaticContact CE2-CE2 3.8Å; F19-F111 HydrophobicContact CE2-CE2 3.8Å; Q36-F111 HydrophobicContact CB-CE1 4.1Å; Q36-F111 HydrophobicContact CB-CZ 4.15Å; Q36-F111 WeakPolarHBondContact O-CZ 3.33Å; G38-F111 VanDerWaalsContact C-CE2 3.46Å; G38-F111 VanDerWaalsContact CA-CE2 3.44Å; Y39-F111 WeakPolarHBondContact O-CA 3.2Å; I40-F111 HydrophobicContact CG2-CB 4.4Å; I40-F111 HydrophobicContact CG2-CD2 4.49Å; A79-F111 HydrophobicContact CB-CD1 3.53Å; A79-F111 HydrophobicContact CB-CD2 3.91Å; A79-F111 HydrophobicContact CB-CE1 3.4Å; A79-F111 HydrophobicContact CB-CE2 3.77Å; A79-F111 HydrophobicContact CB-CG 3.78Å; A79-F111 HydrophobicContact CB-CZ 3.52Å; V109-F111 PolarHBondContact O-N 3.03Å; F111-P113 HydrophobicContact CD1-CG 4.18Å; F111-P113 HydrophobicContact CE1-CB 4.04Å; F111-P113 HydrophobicContact CE1-CG 3.72Å; F111-P113 HydrophobicContact CZ-CB 4.42Å; F111-T121 CarbonylContact O-C 3.58Å; F111-T121 WeakPolarHBondContact O-CA 3.29Å; F111-Q122 WeakPolarHBondContact CB-O 3.4Å; F111-Q122 HydrophobicContact CD1-CB 4.27Å; F111-Q122 PolarHBondContact N-O 3.01Å; F111-Q122 PolarHBondContact O-N 3.04Å; F111-A124 HydrophobicContact CB-CB 3.88Å
112I95.4Very high80.4Confident16 Ų1663.5 Ų63.58%0.08234%0.344CS..EExtended strand (participates in β ladder)trans-113.1111.4178.5-61.1154.9000107.5G38 Y39 H41 T121G38-I112 CarbonylContact C-O 3.58Å; G38-I112 WeakPolarHBondContact CA-O 3.39Å; Y39-I112 HydrophobicContact CD2-CB 4.29Å; Y39-I112 HydrophobicContact CD2-CD1 4.18Å; Y39-I112 HydrophobicContact CE1-CB 4.11Å; Y39-I112 HydrophobicContact CE1-CG2 3.9Å; Y39-I112 HydrophobicContact CE2-CB 3.85Å; Y39-I112 HydrophobicContact CE2-CD1 3.43Å; Y39-I112 VanDerWaalsContact CE2-CD1 3.43Å; Y39-I112 HydrophobicContact CE2-CG1 4.23Å; Y39-I112 HydrophobicContact CE2-CG2 4.2Å; Y39-I112 PolarHBondContact N-O 3.5Å; Y39-I112 PolarHBondContact O-N 3.16Å; Y39-I112 WeakPolarHBondContact OH-CG2 3.48Å; H41-I112 WeakPolarHBondContact NE2-CD1 3.44Å; I112-T121 HydrophobicContact CG1-CG2 3.86Å
113P94.8Very high82.3Confident7 Ų766.1 Ų66.15%0.04535%0.349CS..EExtended strand (participates in β ladder)trans-64.7145.5175.8-14.627000111.6Q36 F111 D116 Q120Q36-P113 VanDerWaalsContact OE1-CG 3.23Å; F111-P113 HydrophobicContact CD1-CG 4.18Å; F111-P113 HydrophobicContact CE1-CB 4.04Å; F111-P113 HydrophobicContact CE1-CG 3.72Å; F111-P113 HydrophobicContact CZ-CB 4.42Å; P113-D116 HydrophobicContact CB-CB 4.03Å; P113-D116 HydrophobicContact CG-CB 4.17Å; P113-Q120 WeakPolarHBondContact CD-O 3.26Å
114E90.6Very high83.8Confident73 Ų7364.2 Ų64.234%0.34133%0.328SS..THydrogen-bonded Turntrans-64.2-44.8177.5-175.5175.7-177.700112.5V37 W76 D116 H176V37-E114 WeakPolarHBondContact CG1-OE2 3.1Å; V37-E114 PolarHBondContact O-N 3.01Å; W76-E114 HydrophobicContact CH2-CB 4.18Å; W76-E114 HydrophobicContact CH2-CG 3.95Å; W76-E114 HydrophobicContact CZ3-CB 3.84Å; W76-E114 HydrophobicContact CZ3-CG 3.87Å; E114-D116 PolarHBondContact O-N 3.19Å; E114-H176 IonicContact OE1-CE1 2.73Å; E114-H176 PolarHBondContact OE1-CE1 3.05Å; E114-H176 IonicContact OE1-ND1 2.97Å; E114-H176 PolarHBondContact OE1-ND1 3.3Å
115D79.1Confident84.7Confident152 Ų15261.7 Ų61.781%0.81332%0.319SS*.THydrogen-bonded Turntrans-81.51.2-172.7-70.8-34.2000113.8Q117D115-Q117 PolarHBondContact O-N 2.7Å
116D67.2Low85.2Confident38 Ų3859 Ų5920%0.20331%0.305CS..  trans-88.993.7-174.7-1695.9000112.2P113 E114 S118 N119 Q120P113-D116 HydrophobicContact CB-CB 4.03Å; P113-D116 HydrophobicContact CG-CB 4.17Å; E114-D116 PolarHBondContact O-N 3.19Å; D116-S118 VanDerWaalsContact CG-OG 3.26Å; D116-S118 PolarHBondContact O-N 3.38Å; D116-S118 WeakPolarHBondContact OD1-CA 3.49Å; D116-S118 WeakPolarHBondContact OD1-CB 3.5Å; D116-S118 PolarHBondContact OD1-N 3.29Å; D116-S118 PolarHBondContact OD1-OG 3.3Å; D116-S118 PolarHBondContact OD2-OG 2.99Å; D116-N119 PolarHBondContact O-N 2.9Å; D116-Q120 WeakPolarHBondContact OD2-CA 3.31Å; D116-Q120 VanDerWaalsContact OD2-CB 3.27Å; D116-Q120 WeakPolarHBondContact OD2-CB 3.3Å; D116-Q120 PolarHBondContact OD2-N 2.83Å
117Q58.8Low85.4Confident204 Ų20459.1 Ų59.195%0.95330%0.304SS*.THydrogen-bonded Turntrans-59.7-13.1172.9-63.3-161.32.700113.7D115D115-Q117 PolarHBondContact O-N 2.7Å
118S63.3Low85.4Confident70 Ų7056.8 Ų56.849%0.4929%0.294SS..THydrogen-bonded Turntrans-93.6-3.5177.275.80000114.3D116 Q120D116-S118 VanDerWaalsContact CG-OG 3.26Å; D116-S118 PolarHBondContact O-N 3.38Å; D116-S118 WeakPolarHBondContact OD1-CA 3.49Å; D116-S118 WeakPolarHBondContact OD1-CB 3.5Å; D116-S118 PolarHBondContact OD1-N 3.29Å; D116-S118 PolarHBondContact OD1-OG 3.3Å; D116-S118 PolarHBondContact OD2-OG 2.99Å; S118-Q120 PolarHBondContact O-N 3.12Å; S118-Q120 WeakPolarHBondContact OG-CG 3.46Å
119N62.1Low85.1Confident116 Ų11653.9 Ų53.962%0.6228%0.279SS*.  trans50.433.6-174.8-82-9.4000113.1D116 T121D116-N119 PolarHBondContact O-N 2.9Å; N119-T121 PolarHBondContact O-N 2.98Å; N119-T121 VanDerWaalsContact O-N 3.15Å
120Q78.1Confident84.4Confident135 Ų13554.4 Ų54.463%0.63128%0.282SS*.  trans-73113.8176.5-74.1-1782.700109.9P113 D116 S118P113-Q120 WeakPolarHBondContact CD-O 3.26Å; D116-Q120 WeakPolarHBondContact OD2-CA 3.31Å; D116-Q120 VanDerWaalsContact OD2-CB 3.27Å; D116-Q120 WeakPolarHBondContact OD2-CB 3.3Å; D116-Q120 PolarHBondContact OD2-N 2.83Å; S118-Q120 PolarHBondContact O-N 3.12Å; S118-Q120 WeakPolarHBondContact OG-CG 3.46Å
121T87.4Confident83.9Confident80 Ų8053.9 Ų53.949%0.49128%0.284SS..  trans-70132.7173.153.30000110.4D110 F111 I112 N119D110-T121 HydrophobicContact CB-CG2 4.18Å; F111-T121 CarbonylContact O-C 3.58Å; F111-T121 WeakPolarHBondContact O-CA 3.29Å; I112-T121 HydrophobicContact CG1-CG2 3.86Å; N119-T121 PolarHBondContact O-N 2.98Å; N119-T121 VanDerWaalsContact O-N 3.15Å
122Q90.6Very high83.3Confident39 Ų3961 Ų6118%0.18232%0.322CS..EExtended strand (participates in β ladder)trans-106137.1169.9-60.9167.64.900109.1W17 Q36 F111 A124W17-Q122 VanDerWaalsContact CD2-OE1 3.28Å; W17-Q122 HydrophobicContact CG-CB 4.49Å; W17-Q122 VanDerWaalsContact CZ2-OE1 3.23Å; Q36-Q122 VanDerWaalsContact OE1-NE2 3.1Å; F111-Q122 WeakPolarHBondContact CB-O 3.4Å; F111-Q122 HydrophobicContact CD1-CB 4.27Å; F111-Q122 PolarHBondContact N-O 3.01Å; F111-Q122 PolarHBondContact O-N 3.04Å; Q122-A124 PolarHBondContact O-N 2.97Å
123Q93.4Very high82.8Confident82 Ų8260.7 Ų60.738%0.38332%0.32SS..EExtended strand (participates in β ladder)trans-76.4117.9174.4-80.5-87.4-56.500110D110D110-Q123 PolarHBondContact OD1-NE2 3.1Å
124A93.9Very high82.4Confident0 Ų066.5 Ų66.50%036%0.358CS..EExtended strand (participates in β ladder)trans-117.2140-179.900000112.1W17 F19 L108 V109 F111 Q122W17-A124 HydrophobicContact CB-CB 3.9Å; W17-A124 CarbonylContact O-C 3.58Å; W17-A124 WeakPolarHBondContact O-CA 3.15Å; F19-A124 HydrophobicContact CB-CB 3.96Å; L108-A124 WeakPolarHBondContact CA-O 3.18Å; V109-A124 PolarHBondContact N-O 3.2Å; V109-A124 PolarHBondContact O-N 3.19Å; F111-A124 HydrophobicContact CB-CB 3.88Å; Q122-A124 PolarHBondContact O-N 2.97Å
125L93.1Very high82.4Confident2 Ų264.9 Ų64.91%0.0135%0.352CS..EExtended strand (participates in β ladder)trans-78.2126.2171.3-171.468.5000109.6P3 I6 L16 W17 I18 F19 L91 T106 L108 Y127P3-L125 HydrophobicContact CB-CD2 4.38Å; I6-L125 HydrophobicContact CD1-CD1 3.98Å; L16-L125 HydrophobicContact CD1-CB 4.19Å; L16-L125 HydrophobicContact CD2-CB 4.42Å; L16-L125 HydrophobicContact CD2-CD2 4.12Å; W17-L125 PolarHBondContact O-N 3.2Å; I18-L125 WeakPolarHBondContact CA-O 3.31Å; F19-L125 PolarHBondContact N-O 2.86Å; L91-L125 HydrophobicContact CD2-CD2 3.43Å; L91-L125 VanDerWaalsContact CD2-CD2 3.43Å; T106-L125 HydrophobicContact CG2-CD1 4.48Å; L108-L125 HydrophobicContact CD2-CB 4.35Å; L108-L125 HydrophobicContact CD2-CD1 4.13Å; L125-Y127 HydrophobicContact CD2-CE2 3.59Å; L125-Y127 HydrophobicContact CG-CD2 4.47Å; L125-Y127 HydrophobicContact CG-CE2 3.93Å
126L91.8Very high83Confident0 Ų060.2 Ų60.20%032%0.324CS..EExtended strand (participates in β ladder)trans-118.1130.6-177.7172.364.6000109.7F19 Y21 I40 Y43 L67 T106 K107 V109 I128F19-L126 HydrophobicContact CD1-CD1 3.92Å; Y21-L126 HydrophobicContact CD1-CD1 3.6Å; Y21-L126 HydrophobicContact CE1-CD1 3.52Å; I40-L126 HydrophobicContact CD1-CD1 4.33Å; I40-L126 HydrophobicContact CD1-CD2 3.76Å; Y43-L126 HydrophobicContact CD2-CD2 4.39Å; Y43-L126 HydrophobicContact CE2-CD2 4.19Å; L67-L126 HydrophobicContact CD1-CD1 3.58Å; L67-L126 HydrophobicContact CD1-CD2 3.84Å; L67-L126 HydrophobicContact CD1-CG 4.23Å; T106-L126 CarbonylContact C-O 3.55Å; T106-L126 VanDerWaalsContact CA-O 3.24Å; T106-L126 WeakPolarHBondContact CA-O 3.26Å; K107-L126 PolarHBondContact N-O 3.1Å; K107-L126 PolarHBondContact O-N 2.67Å; V109-L126 HydrophobicContact CG1-CB 4.32Å; V109-L126 HydrophobicContact CG1-CD2 3.69Å; V109-L126 HydrophobicContact CG2-CB 3.91Å; V109-L126 HydrophobicContact CG2-CD2 4.12Å; L126-I128 HydrophobicContact CD1-CG1 4.17Å; L126-I128 HydrophobicContact CD2-CD1 3.48Å; L126-I128 VanDerWaalsContact CD2-CD1 3.48Å; L126-I128 HydrophobicContact CD2-CG1 3.79Å; L126-I128 HydrophobicContact CG-CD1 3.88Å; L126-I128 HydrophobicContact CG-CG1 3.58Å
127Y89.3Confident84.3Confident13 Ų1361.6 Ų61.65%0.05133%0.331CS..EExtended strand (participates in β ladder)trans-104.1121.4174.7-73.6-101.5000109.7P3 Y21 L94 E98 I105 T106 L125P3-Y127 HydrophobicContact CG-CE1 4.42Å; Y21-Y127 WeakPolarHBondContact CE1-O 3.35Å; Y21-Y127 VanDerWaalsContact CZ-O 3.31Å; Y21-Y127 PolarHBondContact OH-O 3.45Å; L94-Y127 HydrophobicContact CB-CE1 4.03Å; L94-Y127 HydrophobicContact CB-CE2 4.07Å; L94-Y127 HydrophobicContact CD1-CD2 4.36Å; L94-Y127 HydrophobicContact CD1-CE2 3.66Å; L94-Y127 HydrophobicContact CG-CE2 4.42Å; E98-Y127 HydrophobicContact CB-CD1 4.4Å; E98-Y127 HydrophobicContact CG-CD1 3.87Å; E98-Y127 HydrophobicContact CG-CE1 4.43Å; I105-Y127 WeakPolarHBondContact O-CA 3.18Å; T106-Y127 HydrophobicContact CG2-CD1 3.53Å; T106-Y127 HydrophobicContact CG2-CD2 4.37Å; T106-Y127 HydrophobicContact CG2-CE1 3.38Å; T106-Y127 HydrophobicContact CG2-CE2 4.24Å; T106-Y127 HydrophobicContact CG2-CG 4.04Å; L125-Y127 HydrophobicContact CD2-CE2 3.59Å; L125-Y127 HydrophobicContact CG-CD2 4.47Å; L125-Y127 HydrophobicContact CG-CE2 3.93Å
128I87.9Confident86.1Confident7 Ų752.1 Ų52.14%0.03629%0.289CS..EExtended strand (participates in β ladder)trans-129.3128.6-176-45.3178.9000110.6Y43 L67 Y104 I105 K107 L126 T130Y43-I128 HydrophobicContact CD1-CD1 4.08Å; Y43-I128 HydrophobicContact CE1-CD1 3.55Å; L67-I128 HydrophobicContact CB-CD1 4.41Å; L67-I128 HydrophobicContact CB-CG2 3.93Å; L67-I128 HydrophobicContact CD1-CD1 4.39Å; L67-I128 HydrophobicContact CD1-CG1 4.37Å; L67-I128 WeakPolarHBondContact O-CG2 3.23Å; Y104-I128 CarbonylContact C-O 3.55Å; Y104-I128 VanDerWaalsContact CA-O 3.23Å; Y104-I128 WeakPolarHBondContact CA-O 3.37Å; I105-I128 HydrophobicContact CG1-CB 4.25Å; I105-I128 PolarHBondContact N-O 3.37Å; I105-I128 PolarHBondContact O-N 3.21Å; K107-I128 HydrophobicContact CD-CD1 4.26Å; L126-I128 HydrophobicContact CD1-CG1 4.17Å; L126-I128 HydrophobicContact CD2-CD1 3.48Å; L126-I128 VanDerWaalsContact CD2-CD1 3.48Å; L126-I128 HydrophobicContact CD2-CG1 3.79Å; L126-I128 HydrophobicContact CG-CD1 3.88Å; L126-I128 HydrophobicContact CG-CG1 3.58Å; I128-T130 PolarHBondContact O-N 2.73Å
129A85.2Confident87.7Confident0 Ų053.3 Ų53.30%029%0.294CS..EExtended strand (participates in β ladder)trans-77.3115.9165.200000110.2H49 T66 Y104H49-A129 WeakPolarHBondContact CD2-CB 3.32Å; H49-A129 WeakPolarHBondContact NE2-CB 3.48Å; T66-A129 PolarHBondContact OG1-N 2.87Å; T66-A129 PolarHBondContact OG1-O 2.84Å; Y104-A129 HydrophobicContact CD1-CB 4.06Å; Y104-A129 HydrophobicContact CD2-CB 3.98Å; Y104-A129 HydrophobicContact CE1-CB 3.76Å; Y104-A129 HydrophobicContact CE2-CB 3.67Å; Y104-A129 HydrophobicContact CG-CB 4.17Å
130T80.9Confident89.4Confident26 Ų2649.4 Ų49.416%0.1628%0.279CS..  trans-73.6159.9-179.160.20000112.2I105 I128 D132 N133I105-T130 HydrophobicContact CB-CG2 4.27Å; I105-T130 HydrophobicContact CD1-CG2 3.57Å; I105-T130 HydrophobicContact CG1-CG2 3.65Å; I105-T130 HydrophobicContact CG2-CG2 3.7Å; I128-T130 PolarHBondContact O-N 2.73Å; T130-D132 PolarHBondContact O-N 3.35Å; T130-N133 WeakPolarHBondContact O-CB 3.41Å; T130-N133 PolarHBondContact O-N 2.91Å; T130-N133 VanDerWaalsContact O-N 3.08Å
131P83.9Confident90.4Very high72 Ų7245.4 Ų45.447%0.46827%0.265SS..THydrogen-bonded Turntrans-59.4-22.9171.4-26.536.6000114.8N133 F136P131-N133 PolarHBondContact O-N 3.14Å; P131-F136 HydrophobicContact CB-CD1 4.06Å; P131-F136 HydrophobicContact CB-CE1 3.92Å; P131-F136 HydrophobicContact CB-CE2 4.41Å; P131-F136 HydrophobicContact CB-CG 4.35Å; P131-F136 HydrophobicContact CB-CZ 4.1Å; P131-F136 HydrophobicContact CG-CE2 4.45Å; P131-F136 HydrophobicContact CG-CZ 4.3Å; P131-F136 WeakPolarHBondContact O-CB 2.95Å
132D82.2Confident90.9Very high150 Ų15043.4 Ų43.480%0.80225%0.254SS*.THydrogen-bonded Turntrans-73.8-5.2176.2-60.2-36.6000112.9T130T130-D132 PolarHBondContact O-N 3.35Å
133N84.9Confident91.3Very high8 Ų847.2 Ų47.24%0.04327%0.271CS..SBendtrans-66.8131.6176-167.7-38.8000110.5H49 G102 T130 P131 L135 F136H49-N133 PolarHBondContact NE2-ND2 3.16Å; G102-N133 PolarHBondContact O-ND2 2.88Å; T130-N133 WeakPolarHBondContact O-CB 3.41Å; T130-N133 PolarHBondContact O-N 2.91Å; T130-N133 VanDerWaalsContact O-N 3.08Å; P131-N133 PolarHBondContact O-N 3.14Å; N133-L135 PolarHBondContact O-N 3.34Å; N133-L135 WeakPolarHBondContact OD1-CB 3.27Å; N133-L135 PolarHBondContact OD1-N 3.02Å; N133-F136 HydrophobicContact CB-CB 4.39Å; N133-F136 WeakPolarHBondContact O-CB 3.4Å; N133-F136 PolarHBondContact O-N 3Å
134P87.1Confident91.5Very high130 Ų13047.1 Ų47.184%0.84428%0.277SS*.THydrogen-bonded Turntrans-56.3-24.8174.6-26.434.6000114.6F136P134-F136 VanDerWaalsContact C-N 3.33Å
135L89.8Confident91.8Very high39 Ų3947.2 Ų47.220%0.20428%0.277CS..THydrogen-bonded Turntrans-86.90.1176.1-63.4177.7000113.1G50 N133 L137G50-L135 WeakPolarHBondContact CA-O 3.33Å; G50-L135 PolarHBondContact N-O 3.48Å; N133-L135 PolarHBondContact O-N 3.34Å; N133-L135 WeakPolarHBondContact OD1-CB 3.27Å; N133-L135 PolarHBondContact OD1-N 3.02Å; L135-L137 PolarHBondContact O-N 3.4Å; L135-L137 VanDerWaalsContact O-N 3.1Å
136F92.3Very high92Very high54 Ų5447.1 Ų47.124%0.23728%0.276CS..BIsolated β-bridgetrans-68.4109.9174.3-173.6-107.4000110.2W48 T66 I68 P131 N133 P134 G138W48-F136 HydrophobicContact CB-CD2 4.5Å; W48-F136 HydrophobicContact CB-CE2 3.8Å; W48-F136 HydrophobicContact CB-CZ 4.25Å; W48-F136 HydrophobicContact CE3-CE2 4.43Å; W48-F136 HydrophobicContact CE3-CZ 4.08Å; T66-F136 HydrophobicContact CG2-CE2 4.31Å; I68-F136 HydrophobicContact CD1-CE2 3.93Å; I68-F136 HydrophobicContact CD1-CZ 4.2Å; P131-F136 HydrophobicContact CB-CD1 4.06Å; P131-F136 HydrophobicContact CB-CE1 3.92Å; P131-F136 HydrophobicContact CB-CE2 4.41Å; P131-F136 HydrophobicContact CB-CG 4.35Å; P131-F136 HydrophobicContact CB-CZ 4.1Å; P131-F136 HydrophobicContact CG-CE2 4.45Å; P131-F136 HydrophobicContact CG-CZ 4.3Å; P131-F136 WeakPolarHBondContact O-CB 2.95Å; N133-F136 HydrophobicContact CB-CB 4.39Å; N133-F136 WeakPolarHBondContact O-CB 3.4Å; N133-F136 PolarHBondContact O-N 3Å; P134-F136 VanDerWaalsContact C-N 3.33Å; F136-G138 VanDerWaalsContact CE1-CA 3.46Å
137L95.3Very high92.3Very high66 Ų6652 Ų5235%0.34630%0.299SS..  trans-89-11.9180-60179.8000112.6W48 R63 L135W48-L137 PolarHBondContact O-N 3.47Å; R63-L137 HydrophobicContact CG-CD1 3.78Å; L135-L137 PolarHBondContact O-N 3.4Å; L135-L137 VanDerWaalsContact O-N 3.1Å
138G95.6Very high92.7Very high6 Ų652.6 Ų52.66%0.06230%0.302CS..  trans68.7-172.4176.300000115.5W48 R63 F136W48-G138 VanDerWaalsContact CD1-O 3.3Å; W48-G138 PolarHBondContact O-N 3.4Å; W48-G138 VanDerWaalsContact O-N 3.12Å; R63-G138 PolarHBondContact NH1-O 2.94Å; F136-G138 VanDerWaalsContact CE1-CA 3.46Å
139P97.4Very high93.2Very high94 Ų9452.2 Ų52.261%0.6130%0.3SS*.  trans-61.8141.2178.8-17.229.2000112.6W48W48-P139 HydrophobicContact CD2-CB 4.38Å; W48-P139 HydrophobicContact CD2-CG 4.16Å; W48-P139 HydrophobicContact CE3-CG 4.01Å; W48-P139 HydrophobicContact CH2-CB 4.1Å; W48-P139 HydrophobicContact CH2-CG 3.72Å; W48-P139 HydrophobicContact CZ2-CB 3.74Å; W48-P139 HydrophobicContact CZ2-CG 3.87Å; W48-P139 HydrophobicContact CZ3-CG 3.79Å
140A98.1Very high93.8Very high35 Ų3552.7 Ų52.729%0.28930%0.304SS..  trans-153.1164.1170.200000108.4V144 I145A140-V144 HydrophobicContact CB-CB 4.21Å; A140-V144 HydrophobicContact CB-CG1 4.06Å; A140-I145 HydrophobicContact CB-CD1 4.22Å; A140-I145 HydrophobicContact CB-CG1 3.81Å; A140-I145 WeakPolarHBondContact O-CD1 3.43Å
141S98.4Very high94.5Very high51 Ų5153.9 Ų53.936%0.35731%0.311SS..  trans-67.2155.2178.587.50000111.1E143 V144 I145S141-E143 WeakPolarHBondContact CB-OE2 3.42Å; S141-E143 PolarHBondContact O-N 2.84Å; S141-E143 PolarHBondContact OG-N 3.29Å; S141-E143 PolarHBondContact OG-OE2 3.15Å; S141-V144 PolarHBondContact O-N 2.65Å; S141-V144 VanDerWaalsContact O-N 3.15Å; S141-V144 PolarHBondContact OG-N 3.45Å; S141-I145 WeakPolarHBondContact O-CG1 3.48Å; S141-I145 PolarHBondContact O-N 3.28Å
142P98.5Very high95.2Very high38 Ų3853.1 Ų53.125%0.24730%0.299CS..Hα-helixtrans-53.9-34.2175.9-27.636.5000113.3G146 I185 A188P142-G146 WeakPolarHBondContact O-CA 3.35Å; P142-G146 PolarHBondContact O-N 3.02Å; P142-I185 HydrophobicContact CB-CG1 4.12Å; P142-A188 WeakPolarHBondContact O-CB 3.42Å
143E98.4Very high95.8Very high118 Ų11851 Ų5155%0.55129%0.285SS*.Hα-helixtrans-68.2-45.2178.5-55.571.4-154.400111.6S141 G146 H147S141-E143 WeakPolarHBondContact CB-OE2 3.42Å; S141-E143 PolarHBondContact O-N 2.84Å; S141-E143 PolarHBondContact OG-N 3.29Å; S141-E143 PolarHBondContact OG-OE2 3.15Å; E143-G146 PolarHBondContact O-N 2.99Å; E143-H147 VanDerWaalsContact O-CB 3.27Å; E143-H147 WeakPolarHBondContact O-CB 3.42Å; E143-H147 PolarHBondContact O-N 3.32Å
144V98.3Very high96.3Very high81 Ų8151.3 Ų51.349%0.49129%0.289SS..Hα-helixtrans-64-45.5176.3175.10000110.4A140 S141 Q148A140-V144 HydrophobicContact CB-CB 4.21Å; A140-V144 HydrophobicContact CB-CG1 4.06Å; S141-V144 PolarHBondContact O-N 2.65Å; S141-V144 VanDerWaalsContact O-N 3.15Å; S141-V144 PolarHBondContact OG-N 3.45Å; V144-Q148 PolarHBondContact O-N 3.18Å
145I98.6Very high96.6Very high1 Ų153 Ų531%0.00528%0.283CS..Hα-helixtrans-65.4-45.8178.9-63.5173.3000110.5F47 A140 S141 H147 Q148 I149 I185F47-I145 HydrophobicContact CB-CG2 3.84Å; A140-I145 HydrophobicContact CB-CD1 4.22Å; A140-I145 HydrophobicContact CB-CG1 3.81Å; A140-I145 WeakPolarHBondContact O-CD1 3.43Å; S141-I145 WeakPolarHBondContact O-CG1 3.48Å; S141-I145 PolarHBondContact O-N 3.28Å; I145-H147 PolarHBondContact O-N 2.96Å; I145-Q148 PolarHBondContact O-N 3.37Å; I145-I149 HydrophobicContact CG2-CD1 3.65Å; I145-I149 HydrophobicContact CG2-CG1 4.28Å; I145-I149 WeakPolarHBondContact O-CG1 3.16Å; I145-I149 PolarHBondContact O-N 2.74Å; I145-I185 HydrophobicContact CB-CD1 4.12Å; I145-I185 HydrophobicContact CB-CG1 4.12Å; I145-I185 HydrophobicContact CB-CG2 4.47Å; I145-I185 HydrophobicContact CD1-CD1 3.93Å; I145-I185 HydrophobicContact CG2-CD1 3.64Å; I145-I185 HydrophobicContact CG2-CG1 3.96Å; I145-I185 HydrophobicContact CG2-CG2 3.76Å
146G98.3Very high96.6Very high0 Ų053.4 Ų53.40%029%0.287CS..Hα-helixtrans-61.6-42.4179.400000112.1P142 E143 I149 A150P142-G146 WeakPolarHBondContact O-CA 3.35Å; P142-G146 PolarHBondContact O-N 3.02Å; E143-G146 PolarHBondContact O-N 2.99Å; G146-I149 PolarHBondContact O-N 3.31Å; G146-A150 VanDerWaalsContact O-CB 3.3Å; G146-A150 WeakPolarHBondContact O-CB 3.42Å; G146-A150 PolarHBondContact O-N 3.45Å
147H98Very high96.7Very high102 Ų10251.7 Ų51.747%0.47229%0.285SS..Hα-helixtrans-62.1-45.6174.5-175.787.6000112.6E143 I145 A150 T151 L192E143-H147 VanDerWaalsContact O-CB 3.27Å; E143-H147 WeakPolarHBondContact O-CB 3.42Å; E143-H147 PolarHBondContact O-N 3.32Å; I145-H147 PolarHBondContact O-N 2.96Å; H147-A150 PolarHBondContact O-N 2.87Å; H147-T151 WeakPolarHBondContact O-CG2 3.43Å; H147-T151 PolarHBondContact O-N 2.99Å; H147-T151 PolarHBondContact O-OG1 2.92Å; H147-L192 HydrophobicContact CB-CD1 3.72Å
148Q98.1Very high96.8Very high26 Ų2653.2 Ų53.212%0.12129%0.291CS..Hα-helixtrans-60.8-47.7174.5-171.8172.1-4.400110.3P61 V144 I145 A150 T151 R152P61-Q148 PolarHBondContact O-NE2 3.24Å; V144-Q148 PolarHBondContact O-N 3.18Å; I145-Q148 PolarHBondContact O-N 3.37Å; Q148-A150 VanDerWaalsContact C-N 3.35Å; Q148-A150 PolarHBondContact O-N 3.14Å; Q148-T151 PolarHBondContact O-N 3.07Å; Q148-T151 PolarHBondContact O-OG1 3.44Å; Q148-R152 HydrophobicContact CG-CG 3.92Å; Q148-R152 WeakPolarHBondContact O-CB 3.48Å; Q148-R152 WeakPolarHBondContact O-CG 3.49Å; Q148-R152 PolarHBondContact O-N 3.44Å
149I98.3Very high96.9Very high0 Ų053 Ų530%029%0.288CS..Hα-helixtrans-63.7-38.8-179.6-70.6173000112.5F47 R63 I145 G146 T151 N159 L160 L163 I185F47-I149 HydrophobicContact CD1-CD1 3.58Å; F47-I149 HydrophobicContact CE1-CD1 3.87Å; F47-I149 HydrophobicContact CG-CD1 4.26Å; R63-I149 HydrophobicContact CB-CD1 4.3Å; R63-I149 HydrophobicContact CB-CG1 4.03Å; I145-I149 HydrophobicContact CG2-CD1 3.65Å; I145-I149 HydrophobicContact CG2-CG1 4.28Å; I145-I149 WeakPolarHBondContact O-CG1 3.16Å; I145-I149 PolarHBondContact O-N 2.74Å; G146-I149 PolarHBondContact O-N 3.31Å; I149-T151 VanDerWaalsContact C-N 3.28Å; I149-T151 PolarHBondContact O-N 3.06Å; I149-N159 HydrophobicContact CG2-CB 4.2Å; I149-N159 WeakPolarHBondContact O-CB 3.41Å; I149-L160 HydrophobicContact CG2-CB 4.47Å; I149-L160 HydrophobicContact CG2-CD1 4.46Å; I149-L160 PolarHBondContact O-N 3.08Å; I149-L163 HydrophobicContact CB-CD2 4.44Å; I149-L163 HydrophobicContact CD1-CD2 4.16Å; I149-L163 HydrophobicContact CG2-CB 3.89Å; I149-L163 HydrophobicContact CG2-CD2 3.72Å; I149-L163 HydrophobicContact CG2-CG 4.48Å; I149-I185 HydrophobicContact CD1-CG2 3.71Å
150A97.5Very high96.9Very high10 Ų1050 Ų508%0.08327%0.266CS..Hα-helixtrans-67.7-27.6-178.600000113.2G146 H147 Q148 A189 L192 L196G146-A150 VanDerWaalsContact O-CB 3.3Å; G146-A150 WeakPolarHBondContact O-CB 3.42Å; G146-A150 PolarHBondContact O-N 3.45Å; H147-A150 PolarHBondContact O-N 2.87Å; Q148-A150 VanDerWaalsContact C-N 3.35Å; Q148-A150 PolarHBondContact O-N 3.14Å; A150-A189 HydrophobicContact CB-CB 4.39Å; A150-L192 HydrophobicContact CB-CB 4.28Å; A150-L192 HydrophobicContact CB-CD1 4.2Å; A150-L196 HydrophobicContact CB-CD1 3.94Å
151T96.4Very high96.9Very high50 Ų5051.4 Ų51.431%0.30727%0.267SS..Hα-helixtrans-105.5-1.7-171.758.10000114.3H147 Q148 I149 L196H147-T151 WeakPolarHBondContact O-CG2 3.43Å; H147-T151 PolarHBondContact O-N 2.99Å; H147-T151 PolarHBondContact O-OG1 2.92Å; Q148-T151 PolarHBondContact O-N 3.07Å; Q148-T151 PolarHBondContact O-OG1 3.44Å; I149-T151 VanDerWaalsContact C-N 3.28Å; I149-T151 PolarHBondContact O-N 3.06Å; T151-L196 HydrophobicContact CG2-CD1 4.2Å; T151-L196 HydrophobicContact CG2-CD2 4.07Å
152R96.8Very high96.9Very high56 Ų5649.6 Ų49.621%0.21125%0.252CS..  trans-107.4145.8-172.9-60.9-76.1-176.1-113.81.4112.2R55 L60 P61 Q148 N159R55-R152 CarbonylContact O-C 3.56Å; L60-R152 WeakPolarHBondContact O-CD 3.35Å; P61-R152 WeakPolarHBondContact O-CD 3.3Å; P61-R152 PolarHBondContact O-NE 2.85Å; Q148-R152 HydrophobicContact CG-CG 3.92Å; Q148-R152 WeakPolarHBondContact O-CB 3.48Å; Q148-R152 WeakPolarHBondContact O-CG 3.49Å; Q148-R152 PolarHBondContact O-N 3.44Å; R152-N159 HydrophobicContact CB-CB 4.07Å; R152-N159 PolarHBondContact O-N 2.82Å
153Q96.4Very high96.9Very high107 Ų10747.8 Ų47.850%0.524%0.241SC..EExtended strand (participates in β ladder)trans-145.9140.4177.8179.3178.7-8.700109.3R55 G56 H158R55-Q153 CarbonylContact O-C 3.54Å; R55-Q153 VanDerWaalsContact O-C 3.31Å; R55-Q153 WeakPolarHBondContact O-CA 3.42Å; R55-Q153 PolarHBondContact O-N 3Å; G56-Q153 CarbonylContact C-O 3.27Å; G56-Q153 WeakPolarHBondContact CA-O 3.24Å; Q153-H158 PolarHBondContact OE1-CE1 2.71Å; Q153-H158 PolarHBondContact OE1-NE2 2.81Å
154G94.9Very high96.9Very high13 Ų1345 Ų4513%0.13423%0.229CC..EExtended strand (participates in β ladder)trans-126.9-166.8172.200000112H54 R55 G56 T156 G157H54-G154 CarbonylContact O-C 3.52Å; H54-G154 VanDerWaalsContact O-C 3.27Å; H54-G154 WeakPolarHBondContact O-CA 3.06Å; R55-G154 VanDerWaalsContact C-N 3.32Å; R55-G154 PolarHBondContact O-N 2.95Å; G56-G154 WeakPolarHBondContact O-CA 3.46Å; G154-T156 PolarHBondContact O-N 2.79Å; G154-T156 VanDerWaalsContact O-N 3.12Å; G154-G157 PolarHBondContact N-O 3.28Å; G154-G157 VanDerWaalsContact N-O 3.11Å; G154-G157 PolarHBondContact O-N 3Å
155K92.7Very high96.9Very high165 Ų16546.6 Ų46.672%0.71723%0.227SC*.THydrogen-bonded Turntrans-57.5-28.7-177.3-173.9179.2-178.9177.50113.7F53 H54F53-K155 HydrophobicContact CE1-CD 3.81Å; F53-K155 HydrophobicContact CE2-CD 3.91Å; F53-K155 HydrophobicContact CZ-CD 3.38Å; F53-K155 WeakPolarHBondContact O-CB 3.42Å; F53-K155 PolarHBondContact O-N 3.29Å; H54-K155 PolarHBondContact O-N 3.48Å
156T90.4Very high96.9Very high48 Ų4846.6 Ų46.629%0.29423%0.226SC..THydrogen-bonded Turntrans-100.98.9-176-48.10000112.3H54 R55 G154H54-T156 PolarHBondContact ND1-OG1 2.65Å; H54-T156 WeakPolarHBondContact O-CA 3.25Å; H54-T156 WeakPolarHBondContact O-CB 3.41Å; H54-T156 PolarHBondContact O-N 3.23Å; R55-T156 PolarHBondContact NH1-O 2.91Å; G154-T156 PolarHBondContact O-N 2.79Å; G154-T156 VanDerWaalsContact O-N 3.12Å
157G93.8Very high96.9Very high19 Ų1946.6 Ų46.620%0.19623%0.226CC..EExtended strand (participates in β ladder)trans112.7-171.9176.300000113.5G154G154-G157 PolarHBondContact N-O 3.28Å; G154-G157 VanDerWaalsContact N-O 3.11Å; G154-G157 PolarHBondContact O-N 3Å
158H96.9Very high96.9Very high98 Ų9845 Ų4545%0.45422%0.219SC..EExtended strand (participates in β ladder)trans-62.9144.8-178.4-75.6-78.4000111.8R55 Q153 L160 E161R55-H158 PolarHBondContact NH1-O 2.87Å; Q153-H158 PolarHBondContact OE1-CE1 2.71Å; Q153-H158 PolarHBondContact OE1-NE2 2.81Å; H158-L160 PolarHBondContact O-N 2.81Å; H158-E161 WeakPolarHBondContact O-CB 3.35Å; H158-E161 PolarHBondContact O-N 2.88Å
159N98.1Very high96.9Very high0 Ų044.7 Ų44.70%022%0.217CC..Hα-helixtrans-65.9-32.3173-163168.6000111.4R55 G62 R63 I149 R152 E161 Y162 L163R55-N159 HydrophobicContact CB-CB 4.02Å; G62-N159 WeakPolarHBondContact CA-OD1 3.26Å; R63-N159 PolarHBondContact N-OD1 2.96Å; R63-N159 PolarHBondContact O-ND2 2.87Å; R63-N159 PolarHBondContact O-OD1 3.23Å; I149-N159 HydrophobicContact CG2-CB 4.2Å; I149-N159 WeakPolarHBondContact O-CB 3.41Å; R152-N159 HydrophobicContact CB-CB 4.07Å; R152-N159 PolarHBondContact O-N 2.82Å; N159-E161 PolarHBondContact O-N 3.17Å; N159-Y162 VanDerWaalsContact O-CB 3.27Å; N159-Y162 WeakPolarHBondContact O-CB 3.45Å; N159-Y162 PolarHBondContact O-N 2.71Å; N159-L163 PolarHBondContact O-N 2.7Å
160L98.1Very high96.9Very high31 Ų3144.8 Ų44.816%0.16222%0.218CC..Hα-helixtrans-55.6-38.8174.9-174.960.6000112.5I149 H158 Y162 L163 L164 A189 V193I149-L160 HydrophobicContact CG2-CB 4.47Å; I149-L160 HydrophobicContact CG2-CD1 4.46Å; I149-L160 PolarHBondContact O-N 3.08Å; H158-L160 PolarHBondContact O-N 2.81Å; L160-Y162 VanDerWaalsContact C-N 3.3Å; L160-Y162 PolarHBondContact O-N 3.23Å; L160-L163 HydrophobicContact CD1-CD2 4.33Å; L160-L163 PolarHBondContact O-N 2.78Å; L160-L164 HydrophobicContact CD1-CD1 4.32Å; L160-L164 HydrophobicContact CD1-CG 4.21Å; L160-L164 HydrophobicContact CG-CD1 3.96Å; L160-L164 HydrophobicContact CG-CG 4.27Å; L160-L164 WeakPolarHBondContact O-CG 2.86Å; L160-L164 PolarHBondContact O-N 3.02Å; L160-A189 HydrophobicContact CD1-CB 3.91Å; L160-V193 HydrophobicContact CD2-CG2 3.83Å
161E98Very high97Very high65 Ų6549.6 Ų49.630%0.30423%0.234SC..Hα-helixtrans-60.7-39.7176.7-170.4-156.1-179.600111.9R55 H158 N159 L164 R165R55-E161 IonicContact CZ-OE2 3.42Å; R55-E161 IonicContact NH1-OE2 2.7Å; R55-E161 PolarHBondContact NH1-OE2 2.92Å; R55-E161 IonicContact NH2-OE2 3.29Å; H158-E161 WeakPolarHBondContact O-CB 3.35Å; H158-E161 PolarHBondContact O-N 2.88Å; N159-E161 PolarHBondContact O-N 3.17Å; E161-L164 PolarHBondContact O-N 3.49Å; E161-R165 HydrophobicContact CG-CG 4.41Å; E161-R165 WeakPolarHBondContact O-CB 3.24Å; E161-R165 VanDerWaalsContact O-CG 3.27Å; E161-R165 WeakPolarHBondContact O-CG 3.32Å; E161-R165 PolarHBondContact O-N 3.44Å; E161-R165 IonicContact OE1-CZ 2.98Å; E161-R165 VanDerWaalsContact OE1-CZ 3.22Å; E161-R165 IonicContact OE1-NE 3.45Å; E161-R165 PolarHBondContact OE1-NE 2.9Å; E161-R165 IonicContact OE1-NH2 3.8Å; E161-R165 PolarHBondContact OE1-NH2 3.3Å
162Y98.1Very high97Very high13 Ų1356.1 Ų56.15%0.05125%0.253CS..Hα-helixtrans-60.2-47.3176.7179.6-79.5000111.3W26 F47 R55 V64 V65 N159 L160 L166W26-Y162 HydrophobicContact CH2-CD1 4.31Å; W26-Y162 AromaticContact CH2-CD2 3.5Å; W26-Y162 HydrophobicContact CH2-CD2 3.5Å; W26-Y162 VanDerWaalsContact CH2-CD2 3.5Å; W26-Y162 HydrophobicContact CH2-CE1 4.47Å; W26-Y162 AromaticContact CH2-CE2 3.72Å; W26-Y162 HydrophobicContact CH2-CE2 3.72Å; W26-Y162 AromaticContact CH2-CG 3.82Å; W26-Y162 HydrophobicContact CH2-CG 3.82Å; W26-Y162 AromaticContact CZ2-CD2 3.81Å; W26-Y162 HydrophobicContact CZ2-CD2 3.81Å; W26-Y162 HydrophobicContact CZ2-CE2 4.28Å; W26-Y162 HydrophobicContact CZ2-CG 4.31Å; F47-Y162 AromaticContact CE1-CD1 3.88Å; F47-Y162 HydrophobicContact CE1-CD1 3.88Å; F47-Y162 AromaticContact CE1-CE1 3.79Å; F47-Y162 HydrophobicContact CE1-CE1 3.79Å; F47-Y162 HydrophobicContact CZ-CD1 4.48Å; F47-Y162 HydrophobicContact CZ-CE1 4.29Å; R55-Y162 HydrophobicContact CG-CD2 4.32Å; V64-Y162 HydrophobicContact CB-CE1 4.16Å; V64-Y162 HydrophobicContact CB-CE2 4.17Å; V64-Y162 HydrophobicContact CG1-CD2 4.15Å; V64-Y162 HydrophobicContact CG1-CE1 4.29Å; V64-Y162 HydrophobicContact CG1-CE2 3.87Å; V64-Y162 HydrophobicContact CG1-CG 4.46Å; V65-Y162 HydrophobicContact CG1-CE1 4.44Å; V65-Y162 HydrophobicContact CG2-CE1 4.43Å; V65-Y162 WeakPolarHBondContact CG2-OH 3.43Å; V65-Y162 PolarHBondContact N-OH 3.43Å; N159-Y162 VanDerWaalsContact O-CB 3.27Å; N159-Y162 WeakPolarHBondContact O-CB 3.45Å; N159-Y162 PolarHBondContact O-N 2.71Å; L160-Y162 VanDerWaalsContact C-N 3.3Å; L160-Y162 PolarHBondContact O-N 3.23Å; Y162-L166 PolarHBondContact O-N 2.61Å; Y162-L166 VanDerWaalsContact O-N 3.14Å
163L98.6Very high97Very high0 Ų055.5 Ų55.50%026%0.257CS..Hα-helixtrans-61.3-49.9179.5172.462.6000111F47 I149 N159 L160 R165 L166 A167 L182 I185 E186 A189F47-L163 HydrophobicContact CE1-CB 4.5Å; F47-L163 HydrophobicContact CE1-CD1 4.04Å; F47-L163 HydrophobicContact CE2-CD1 3.96Å; F47-L163 HydrophobicContact CZ-CD1 3.45Å; F47-L163 VanDerWaalsContact CZ-CD1 3.45Å; I149-L163 HydrophobicContact CB-CD2 4.44Å; I149-L163 HydrophobicContact CD1-CD2 4.16Å; I149-L163 HydrophobicContact CG2-CB 3.89Å; I149-L163 HydrophobicContact CG2-CD2 3.72Å; I149-L163 HydrophobicContact CG2-CG 4.48Å; N159-L163 PolarHBondContact O-N 2.7Å; L160-L163 HydrophobicContact CD1-CD2 4.33Å; L160-L163 PolarHBondContact O-N 2.78Å; L163-R165 PolarHBondContact O-N 3.35Å; L163-L166 PolarHBondContact O-N 3.43Å; L163-A167 WeakPolarHBondContact O-CB 3.49Å; L163-A167 PolarHBondContact O-N 3.41Å; L163-L182 HydrophobicContact CD1-CD1 3.61Å; L163-I185 HydrophobicContact CD1-CG2 3.95Å; L163-I185 HydrophobicContact CD2-CG2 3.8Å; L163-E186 HydrophobicContact CD1-CB 4.4Å; L163-E186 HydrophobicContact CD2-CB 4.45Å; L163-E186 HydrophobicContact CG-CB 4.41Å; L163-A189 HydrophobicContact CD2-CB 3.72Å
164L98.4Very high97Very high60 Ų6050.4 Ų50.431%0.31423%0.233SC..Hα-helixtrans-65.1-37.9-178-65.2177.9000112.5L160 E161 A167 E168 E186 L190L160-L164 HydrophobicContact CD1-CD1 4.32Å; L160-L164 HydrophobicContact CD1-CG 4.21Å; L160-L164 HydrophobicContact CG-CD1 3.96Å; L160-L164 HydrophobicContact CG-CG 4.27Å; L160-L164 WeakPolarHBondContact O-CG 2.86Å; L160-L164 PolarHBondContact O-N 3.02Å; E161-L164 PolarHBondContact O-N 3.49Å; L164-A167 PolarHBondContact O-N 3.15Å; L164-E168 VanDerWaalsContact O-CB 3.29Å; L164-E168 WeakPolarHBondContact O-CB 3.44Å; L164-E168 PolarHBondContact O-N 2.76Å; L164-E186 HydrophobicContact CD2-CG 3.96Å; L164-L190 HydrophobicContact CD2-CD1 4.31Å; L164-L190 HydrophobicContact CD2-CD2 4.07Å; L164-L190 HydrophobicContact CD2-CG 4.35Å
165R98.5Very high97.1Very high115 Ų11554.5 Ų54.543%0.43426%0.258SS..Hα-helixtrans-66.1-37.6175.8-73.9-176.8-178.7-83.60.6112.6W26 E161 L163 F169W26-R165 VanDerWaalsContact CD1-CD 3.49Å; W26-R165 HydrophobicContact CD2-CB 3.73Å; W26-R165 HydrophobicContact CD2-CG 4.49Å; W26-R165 HydrophobicContact CE3-CB 3.81Å; W26-R165 HydrophobicContact CG-CB 4.2Å; W26-R165 HydrophobicContact CH2-CB 4.22Å; W26-R165 HydrophobicContact CZ2-CB 4.16Å; W26-R165 HydrophobicContact CZ3-CB 4.06Å; W26-R165 VanDerWaalsContact NE1-CD 3.26Å; E161-R165 HydrophobicContact CG-CG 4.41Å; E161-R165 WeakPolarHBondContact O-CB 3.24Å; E161-R165 VanDerWaalsContact O-CG 3.27Å; E161-R165 WeakPolarHBondContact O-CG 3.32Å; E161-R165 PolarHBondContact O-N 3.44Å; E161-R165 IonicContact OE1-CZ 2.98Å; E161-R165 VanDerWaalsContact OE1-CZ 3.22Å; E161-R165 IonicContact OE1-NE 3.45Å; E161-R165 PolarHBondContact OE1-NE 2.9Å; E161-R165 IonicContact OE1-NH2 3.8Å; E161-R165 PolarHBondContact OE1-NH2 3.3Å; L163-R165 PolarHBondContact O-N 3.35Å; R165-F169 PolarHBondContact O-N 2.85Å
166L98.4Very high97.2Very high0 Ų051.8 Ų51.80%025%0.247CC..Hα-helixtrans-69.6-43.5175.6-175.458.4000111.5V25 W26 F47 V65 Y162 L163 E168 F169 M170 L182V25-L166 HydrophobicContact CG2-CD1 4.07Å; W26-L166 HydrophobicContact CZ3-CB 4.01Å; F47-L166 HydrophobicContact CE2-CD2 4.26Å; F47-L166 HydrophobicContact CZ-CD2 3.95Å; V65-L166 HydrophobicContact CG1-CD2 3.71Å; V65-L166 HydrophobicContact CG2-CD2 4.22Å; Y162-L166 PolarHBondContact O-N 2.61Å; Y162-L166 VanDerWaalsContact O-N 3.14Å; L163-L166 PolarHBondContact O-N 3.43Å; L166-E168 VanDerWaalsContact C-N 3.3Å; L166-E168 PolarHBondContact O-N 2.7Å; L166-F169 HydrophobicContact CD1-CD1 4.42Å; L166-F169 WeakPolarHBondContact O-CB 3.45Å; L166-F169 PolarHBondContact O-N 3.48Å; L166-M170 WeakPolarHBondContact O-CG 3.27Å; L166-M170 PolarHBondContact O-N 3.43Å; L166-L182 HydrophobicContact CB-CD1 4.37Å; L166-L182 HydrophobicContact CD2-CD1 4.06Å; L166-L182 HydrophobicContact CG-CD1 4.13Å; L166-L182 HydrophobicContact CG-CD2 4.12Å
167A98.5Very high97.4Very high0 Ų050.9 Ų50.90%024%0.242CC..Hα-helixtrans-60.4-41.1175.100000111.8L163 L164 M170 R171 L182 F183 E186L163-A167 WeakPolarHBondContact O-CB 3.49Å; L163-A167 PolarHBondContact O-N 3.41Å; L164-A167 PolarHBondContact O-N 3.15Å; A167-M170 PolarHBondContact O-N 2.85Å; A167-R171 WeakPolarHBondContact O-CG 3.33Å; A167-R171 PolarHBondContact O-N 3.26Å; A167-L182 HydrophobicContact CB-CD1 4.39Å; A167-L182 HydrophobicContact CB-CD2 4.43Å; A167-L182 HydrophobicContact CB-CG 4.38Å; A167-F183 HydrophobicContact CB-CE1 4.27Å; A167-E186 VanDerWaalsContact CB-CD 3.48Å; A167-E186 HydrophobicContact CB-CG 4.44Å; A167-E186 WeakPolarHBondContact CB-OE1 3.18Å; A167-E186 WeakPolarHBondContact CB-OE2 3.21Å
168E98.5Very high97.5Very high69 Ų6956.1 Ų56.132%0.32227%0.265SS..Hα-helixtrans-65.9-40.7177.1-170.865.4176.600112.7L164 L166 R171 R172L164-E168 VanDerWaalsContact O-CB 3.29Å; L164-E168 WeakPolarHBondContact O-CB 3.44Å; L164-E168 PolarHBondContact O-N 2.76Å; L166-E168 VanDerWaalsContact C-N 3.3Å; L166-E168 PolarHBondContact O-N 2.7Å; E168-R171 PolarHBondContact O-N 2.82Å; E168-R172 HydrophobicContact CG-CG 4.41Å; E168-R172 WeakPolarHBondContact O-CB 3.33Å; E168-R172 WeakPolarHBondContact O-CG 3.37Å; E168-R172 PolarHBondContact O-N 2.61Å; E168-R172 IonicContact OE1-CZ 2.78Å; E168-R172 IonicContact OE1-NE 2.79Å; E168-R172 PolarHBondContact OE1-NE 2.88Å; E168-R172 IonicContact OE1-NH2 3.51Å; E168-R172 PolarHBondContact OE1-NH2 3.48Å
169F98.3Very high97.5Very high19 Ų1952.1 Ų52.18%0.08325%0.247CC..Hα-helixtrans-56.8-50.2171.6166.6-98.8000110.9V25 V37 V78 R165 L166 R171 R172 S173V25-F169 HydrophobicContact CB-CD1 4.04Å; V25-F169 HydrophobicContact CB-CD2 3.87Å; V25-F169 HydrophobicContact CB-CE1 4.19Å; V25-F169 HydrophobicContact CB-CE2 4.02Å; V25-F169 HydrophobicContact CB-CG 3.88Å; V25-F169 HydrophobicContact CB-CZ 4.19Å; V25-F169 HydrophobicContact CG1-CD1 4.21Å; V25-F169 HydrophobicContact CG1-CE1 4.01Å; V25-F169 HydrophobicContact CG1-CE2 4.49Å; V25-F169 HydrophobicContact CG1-CZ 4.17Å; V25-F169 HydrophobicContact CG2-CB 3.81Å; V25-F169 HydrophobicContact CG2-CD1 3.81Å; V25-F169 HydrophobicContact CG2-CD2 4.01Å; V25-F169 HydrophobicContact CG2-CE1 4.44Å; V25-F169 HydrophobicContact CG2-CG 3.57Å; V37-F169 HydrophobicContact CG2-CE2 4.45Å; V78-F169 HydrophobicContact CG2-CD2 4.44Å; V78-F169 HydrophobicContact CG2-CE2 3.41Å; V78-F169 VanDerWaalsContact CG2-CE2 3.41Å; V78-F169 HydrophobicContact CG2-CZ 3.6Å; R165-F169 PolarHBondContact O-N 2.85Å; L166-F169 HydrophobicContact CD1-CD1 4.42Å; L166-F169 WeakPolarHBondContact O-CB 3.45Å; L166-F169 PolarHBondContact O-N 3.48Å; F169-R171 PolarHBondContact O-N 3.26Å; F169-R172 PolarHBondContact O-N 2.97Å; F169-S173 WeakPolarHBondContact O-CB 3.34Å; F169-S173 PolarHBondContact O-N 2.96Å
170M98.1Very high97.4Very high2 Ų256 Ų561%0.0127%0.273CS..Hα-helixtrans-60.6-43.1179.9-70.1-57.3-63.400112.2R45 W76 L166 A167 R172 C174 V177 D179 L182 F183R45-M170 PolarHBondContact NH2-SD 3.28Å; W76-M170 HydrophobicContact CB-CE 4.19Å; W76-M170 HydrophobicContact CB-SD 4.41Å; L166-M170 WeakPolarHBondContact O-CG 3.27Å; L166-M170 PolarHBondContact O-N 3.43Å; A167-M170 PolarHBondContact O-N 2.85Å; M170-R172 PolarHBondContact O-N 3.36Å; M170-C174 HydrophobicContact CE-CB 3.91Å; M170-C174 CarbonylContact O-C 3.39Å; M170-C174 VanDerWaalsContact O-CA 3.29Å; M170-C174 WeakPolarHBondContact O-CA 3.4Å; M170-C174 PolarHBondContact O-N 3.3Å; M170-C174 VanDerWaalsContact O-O 3.13Å; M170-C174 HydrophobicContact SD-CB 4.25Å; M170-V177 HydrophobicContact CE-CB 3.98Å; M170-V177 HydrophobicContact CE-CG1 3.74Å; M170-D179 HydrophobicContact CE-CB 4.33Å; M170-L182 HydrophobicContact CB-CD2 4.02Å; M170-L182 HydrophobicContact CG-CD2 3.48Å; M170-L182 VanDerWaalsContact CG-CD2 3.48Å; M170-F183 HydrophobicContact CB-CZ 4.05Å
171R97.9Very high97.5Very high111 Ų11155.9 Ų55.942%0.41927%0.271SS..Hα-helixtrans-63.9-40.9177.4-73-177-176105.14.4113.7A167 E168 F169 F183 E186A167-R171 WeakPolarHBondContact O-CG 3.33Å; A167-R171 PolarHBondContact O-N 3.26Å; E168-R171 PolarHBondContact O-N 2.82Å; F169-R171 PolarHBondContact O-N 3.26Å; R171-F183 HydrophobicContact CG-CE1 3.93Å; R171-F183 HydrophobicContact CG-CZ 4.02Å; R171-E186 IonicContact CZ-OE1 3.22Å; R171-E186 IonicContact CZ-OE2 3.01Å; R171-E186 IonicContact NH1-OE1 3.63Å; R171-E186 PolarHBondContact NH1-OE1 3.43Å; R171-E186 IonicContact NH1-OE2 2.61Å; R171-E186 PolarHBondContact NH1-OE2 3.08Å; R171-E186 IonicContact NH2-OE1 2.77Å; R171-E186 PolarHBondContact NH2-OE1 2.83Å; R171-E186 VanDerWaalsContact NH2-OE1 3.15Å; R171-E186 IonicContact NH2-OE2 2.7Å; R171-E186 PolarHBondContact NH2-OE2 3.36Å
172R97.4Very high97.5Very high187 Ų18752.9 Ų52.971%0.70626%0.257SS*.Hα-helixtrans-85.4-43.5-173.2-71.3-170.2-178.7-171.18.3113.1E168 F169 M170E168-R172 HydrophobicContact CG-CG 4.41Å; E168-R172 WeakPolarHBondContact O-CB 3.33Å; E168-R172 WeakPolarHBondContact O-CG 3.37Å; E168-R172 PolarHBondContact O-N 2.61Å; E168-R172 IonicContact OE1-CZ 2.78Å; E168-R172 IonicContact OE1-NE 2.79Å; E168-R172 PolarHBondContact OE1-NE 2.88Å; E168-R172 IonicContact OE1-NH2 3.51Å; E168-R172 PolarHBondContact OE1-NH2 3.48Å; F169-R172 PolarHBondContact O-N 2.97Å; M170-R172 PolarHBondContact O-N 3.36Å
173S96.9Very high97.5Very high43 Ų4354.7 Ų54.730%0.30127%0.265SS..Hα-helixtrans-99.5-19.8-171.3-62.20000112.7F169 P175F169-S173 WeakPolarHBondContact O-CB 3.34Å; F169-S173 PolarHBondContact O-N 2.96Å; S173-P175 VanDerWaalsContact C-CD 3.46Å
174C96.3Very high97.5Very high0 Ų056.9 Ų56.90%028%0.28CS..  trans-134.649.5-178.9-52.60000111.6W76 M170 H176 V177W76-C174 HydrophobicContact CE3-CB 4.37Å; M170-C174 HydrophobicContact CE-CB 3.91Å; M170-C174 CarbonylContact O-C 3.39Å; M170-C174 VanDerWaalsContact O-CA 3.29Å; M170-C174 WeakPolarHBondContact O-CA 3.4Å; M170-C174 PolarHBondContact O-N 3.3Å; M170-C174 VanDerWaalsContact O-O 3.13Å; M170-C174 HydrophobicContact SD-CB 4.25Å; C174-H176 PolarHBondContact O-N 3.44Å; C174-V177 HydrophobicContact CB-CB 4.05Å; C174-V177 HydrophobicContact CB-CG2 3.77Å; C174-V177 WeakPolarHBondContact O-CB 3.29Å; C174-V177 PolarHBondContact O-N 3.29Å
175P96.4Very high97.5Very high99 Ų9954 Ų5464%0.64327%0.265SS*.THydrogen-bonded Turntrans-63.2-18.6-17126.9-36.4000114.3S173S173-P175 VanDerWaalsContact C-CD 3.46Å
176H95.4Very high97.5Very high108 Ų10849 Ų4950%0.525%0.247SC..THydrogen-bonded Turntrans-90.3-2.2179.164.5-85.3000112.9W76 E114 C174W76-H176 AromaticContact CE2-NE2 3.95Å; W76-H176 AromaticContact CH2-CE1 3.5Å; W76-H176 VanDerWaalsContact CH2-CE1 3.5Å; W76-H176 WeakPolarHBondContact CH2-CE1 3.41Å; W76-H176 AromaticContact CH2-NE2 3.05Å; W76-H176 WeakPolarHBondContact CH2-NE2 3.3Å; W76-H176 AromaticContact CZ2-NE2 3.2Å; W76-H176 WeakPolarHBondContact CZ2-NE2 3.27Å; W76-H176 AromaticContact CZ3-CE1 3.75Å; W76-H176 AromaticContact CZ3-NE2 3.73Å; E114-H176 IonicContact OE1-CE1 2.73Å; E114-H176 PolarHBondContact OE1-CE1 3.05Å; E114-H176 IonicContact OE1-ND1 2.97Å; E114-H176 PolarHBondContact OE1-ND1 3.3Å; C174-H176 PolarHBondContact O-N 3.44Å
177V95.4Very high97.5Very high30 Ų3052 Ų5218%0.18227%0.272CS..  trans-102.9125.5-176.9-176.70000109.7W76 M170 C174W76-V177 VanDerWaalsContact CD1-CG1 3.46Å; W76-V177 HydrophobicContact CD2-CG2 3.53Å; W76-V177 HydrophobicContact CE3-CG2 4.19Å; W76-V177 HydrophobicContact CG-CB 4.4Å; W76-V177 HydrophobicContact CG-CG1 4Å; W76-V177 HydrophobicContact CG-CG2 3.68Å; W76-V177 HydrophobicContact CZ2-CG2 3.92Å; M170-V177 HydrophobicContact CE-CB 3.98Å; M170-V177 HydrophobicContact CE-CG1 3.74Å; C174-V177 HydrophobicContact CB-CB 4.05Å; C174-V177 HydrophobicContact CB-CG2 3.77Å; C174-V177 WeakPolarHBondContact O-CB 3.29Å; C174-V177 PolarHBondContact O-N 3.29Å
178D94.6Very high97.5Very high128 Ų12852.9 Ų52.968%0.68428%0.279SS*.  trans-86.5127.2170.8-16817000110.7
179D96.6Very high97.5Very high14 Ų1449.6 Ų49.68%0.07526%0.264CS..  trans-126.877.4172-170-19.5000108.9R45 M170 H181 L182 F183R45-D179 IonicContact CZ-OD2 3.41Å; R45-D179 IonicContact NE-OD2 3.15Å; R45-D179 PolarHBondContact NE-OD2 3.32Å; R45-D179 IonicContact NH2-OD2 3.41Å; R45-D179 PolarHBondContact NH2-OD2 2.77Å; M170-D179 HydrophobicContact CE-CB 4.33Å; D179-H181 PolarHBondContact O-N 3.27Å; D179-H181 PolarHBondContact OD1-N 3.38Å; D179-L182 HydrophobicContact CB-CB 4Å; D179-L182 HydrophobicContact CB-CD2 4.5Å; D179-L182 PolarHBondContact O-N 3.37Å; D179-L182 VanDerWaalsContact O-N 3.16Å; D179-L182 WeakPolarHBondContact OD1-CB 3.27Å; D179-L182 PolarHBondContact OD1-N 3.36Å; D179-L182 WeakPolarHBondContact OD2-CB 3.44Å; D179-F183 HydrophobicContact CB-CD2 4.42Å; D179-F183 HydrophobicContact CB-CE2 4.36Å; D179-F183 WeakPolarHBondContact O-CD2 3.44Å; D179-F183 PolarHBondContact O-N 3.23Å
180P97.6Very high97.5Very high83 Ų8352.3 Ų52.354%0.53928%0.279SS..Hα-helixtrans-63.4-27.3-174.724-34.2000112.1S184P180-S184 WeakPolarHBondContact O-CB 3.39Å; P180-S184 PolarHBondContact O-N 3.39Å; P180-S184 PolarHBondContact O-OG 3.07Å
181H98.4Very high97.4Very high28 Ų2855.1 Ų55.113%0.1330%0.302CS..Hα-helixtrans-65.6-49.7175.7-177.680.3000110.8R46 F47 W48 D179 S184 I185R46-H181 WeakPolarHBondContact CD-ND1 3.25Å; F47-H181 AromaticContact CD2-CD2 3.9Å; F47-H181 AromaticContact CD2-NE2 3.75Å; F47-H181 PolarHBondContact N-NE2 3.34Å; F47-H181 VanDerWaalsContact N-NE2 3.19Å; W48-H181 AromaticContact NE1-CE1 3.77Å; D179-H181 PolarHBondContact O-N 3.27Å; D179-H181 PolarHBondContact OD1-N 3.38Å; H181-S184 PolarHBondContact O-OG 2.8Å; H181-I185 VanDerWaalsContact CE1-CD1 3.48Å; H181-I185 WeakPolarHBondContact CE1-CD1 2.85Å; H181-I185 WeakPolarHBondContact NE2-CD1 3.33Å; H181-I185 VanDerWaalsContact O-CD1 3.31Å; H181-I185 WeakPolarHBondContact O-CD1 3.38Å; H181-I185 VanDerWaalsContact O-CG1 3.3Å; H181-I185 WeakPolarHBondContact O-CG1 3.39Å; H181-I185 PolarHBondContact O-N 2.9Å
182L98.6Very high97.2Very high1 Ų152.2 Ų52.21%0.00530%0.295CS..Hα-helixtrans-62.5-50.7177.8174.962.3000112F47 L163 L166 A167 M170 D179 I185 E186F47-L182 HydrophobicContact CE2-CD1 3.55Å; F47-L182 HydrophobicContact CZ-CD1 3.79Å; L163-L182 HydrophobicContact CD1-CD1 3.61Å; L166-L182 HydrophobicContact CB-CD1 4.37Å; L166-L182 HydrophobicContact CD2-CD1 4.06Å; L166-L182 HydrophobicContact CG-CD1 4.13Å; L166-L182 HydrophobicContact CG-CD2 4.12Å; A167-L182 HydrophobicContact CB-CD1 4.39Å; A167-L182 HydrophobicContact CB-CD2 4.43Å; A167-L182 HydrophobicContact CB-CG 4.38Å; M170-L182 HydrophobicContact CB-CD2 4.02Å; M170-L182 HydrophobicContact CG-CD2 3.48Å; M170-L182 VanDerWaalsContact CG-CD2 3.48Å; D179-L182 HydrophobicContact CB-CB 4Å; D179-L182 HydrophobicContact CB-CD2 4.5Å; D179-L182 PolarHBondContact O-N 3.37Å; D179-L182 VanDerWaalsContact O-N 3.16Å; D179-L182 WeakPolarHBondContact OD1-CB 3.27Å; D179-L182 PolarHBondContact OD1-N 3.36Å; D179-L182 WeakPolarHBondContact OD2-CB 3.44Å; L182-I185 PolarHBondContact O-N 3.39Å; L182-E186 PolarHBondContact O-N 3.34Å
183F98.6Very high96.9Very high52 Ų5245.1 Ų45.123%0.22827%0.272CS..Hα-helixtrans-73.4-31.1-172.4-67.9-57.7000113.3A167 M170 R171 D179 E186 A187A167-F183 HydrophobicContact CB-CE1 4.27Å; M170-F183 HydrophobicContact CB-CZ 4.05Å; R171-F183 HydrophobicContact CG-CE1 3.93Å; R171-F183 HydrophobicContact CG-CZ 4.02Å; D179-F183 HydrophobicContact CB-CD2 4.42Å; D179-F183 HydrophobicContact CB-CE2 4.36Å; D179-F183 WeakPolarHBondContact O-CD2 3.44Å; D179-F183 PolarHBondContact O-N 3.23Å; F183-E186 WeakPolarHBondContact CD1-OE2 3.14Å; F183-E186 PolarHBondContact O-N 3.36Å; F183-A187 WeakPolarHBondContact O-CB 3.44Å; F183-A187 PolarHBondContact O-N 2.85Å
184S98.6Very high96.6Very high45 Ų4547.2 Ų47.232%0.31529%0.285SS..Hα-helixtrans-66.6-39.8172.558.60000112.3P180 H181 A187 A188P180-S184 WeakPolarHBondContact O-CB 3.39Å; P180-S184 PolarHBondContact O-N 3.39Å; P180-S184 PolarHBondContact O-OG 3.07Å; H181-S184 PolarHBondContact O-OG 2.8Å; S184-A187 PolarHBondContact O-N 2.78Å; S184-A188 WeakPolarHBondContact O-CB 3.35Å; S184-A188 PolarHBondContact O-N 3.42Å
185I98.8Very high96.2Very high0 Ų055.7 Ų55.70%032%0.318CS..Hα-helixtrans-66.5-41.8175.4-70.7166.9000111F47 P142 I145 I149 L163 H181 L182 A188 A189F47-I185 HydrophobicContact CB-CD1 3.94Å; F47-I185 HydrophobicContact CD2-CD1 3.73Å; F47-I185 HydrophobicContact CG-CD1 4.06Å; P142-I185 HydrophobicContact CB-CG1 4.12Å; I145-I185 HydrophobicContact CB-CD1 4.12Å; I145-I185 HydrophobicContact CB-CG1 4.12Å; I145-I185 HydrophobicContact CB-CG2 4.47Å; I145-I185 HydrophobicContact CD1-CD1 3.93Å; I145-I185 HydrophobicContact CG2-CD1 3.64Å; I145-I185 HydrophobicContact CG2-CG1 3.96Å; I145-I185 HydrophobicContact CG2-CG2 3.76Å; I149-I185 HydrophobicContact CD1-CG2 3.71Å; L163-I185 HydrophobicContact CD1-CG2 3.95Å; L163-I185 HydrophobicContact CD2-CG2 3.8Å; H181-I185 VanDerWaalsContact CE1-CD1 3.48Å; H181-I185 WeakPolarHBondContact CE1-CD1 2.85Å; H181-I185 WeakPolarHBondContact NE2-CD1 3.33Å; H181-I185 VanDerWaalsContact O-CD1 3.31Å; H181-I185 WeakPolarHBondContact O-CD1 3.38Å; H181-I185 VanDerWaalsContact O-CG1 3.3Å; H181-I185 WeakPolarHBondContact O-CG1 3.39Å; H181-I185 PolarHBondContact O-N 2.9Å; L182-I185 PolarHBondContact O-N 3.39Å; I185-A188 PolarHBondContact O-N 3.22Å; I185-A189 WeakPolarHBondContact O-CB 3.43Å; I185-A189 PolarHBondContact O-N 2.79Å
186E98.6Very high95.6Very high10 Ų1054 Ų545%0.04730%0.303CS..Hα-helixtrans-59.3-48.2175.3-172.5-173.1-162.200112.1L163 L164 A167 R171 L182 F183 A188 A189 L190L163-E186 HydrophobicContact CD1-CB 4.4Å; L163-E186 HydrophobicContact CD2-CB 4.45Å; L163-E186 HydrophobicContact CG-CB 4.41Å; L164-E186 HydrophobicContact CD2-CG 3.96Å; A167-E186 VanDerWaalsContact CB-CD 3.48Å; A167-E186 HydrophobicContact CB-CG 4.44Å; A167-E186 WeakPolarHBondContact CB-OE1 3.18Å; A167-E186 WeakPolarHBondContact CB-OE2 3.21Å; R171-E186 IonicContact CZ-OE1 3.22Å; R171-E186 IonicContact CZ-OE2 3.01Å; R171-E186 IonicContact NH1-OE1 3.63Å; R171-E186 PolarHBondContact NH1-OE1 3.43Å; R171-E186 IonicContact NH1-OE2 2.61Å; R171-E186 PolarHBondContact NH1-OE2 3.08Å; R171-E186 IonicContact NH2-OE1 2.77Å; R171-E186 PolarHBondContact NH2-OE1 2.83Å; R171-E186 VanDerWaalsContact NH2-OE1 3.15Å; R171-E186 IonicContact NH2-OE2 2.7Å; R171-E186 PolarHBondContact NH2-OE2 3.36Å; L182-E186 PolarHBondContact O-N 3.34Å; F183-E186 WeakPolarHBondContact CD1-OE2 3.14Å; F183-E186 PolarHBondContact O-N 3.36Å; E186-A188 VanDerWaalsContact C-N 3.34Å; E186-A188 PolarHBondContact O-N 3.31Å; E186-A189 PolarHBondContact O-N 2.91Å; E186-L190 HydrophobicContact CG-CD1 3.89Å; E186-L190 HydrophobicContact CG-CG 4.35Å; E186-L190 WeakPolarHBondContact O-CB 3.44Å; E186-L190 WeakPolarHBondContact O-CG 3.42Å; E186-L190 PolarHBondContact O-N 3.12Å
187A98.5Very high94.9Very high63 Ų6354.3 Ų54.352%0.52131%0.308SS..Hα-helixtrans-58.4-46.4176.200000111.5F183 S184 A189 L190 A191F183-A187 WeakPolarHBondContact O-CB 3.44Å; F183-A187 PolarHBondContact O-N 2.85Å; S184-A187 PolarHBondContact O-N 2.78Å; A187-A189 PolarHBondContact O-N 3.49Å; A187-L190 PolarHBondContact O-N 3.12Å; A187-A191 WeakPolarHBondContact O-CB 3.34Å; A187-A191 PolarHBondContact O-N 3.14Å
188A98.4Very high93.7Very high18 Ų1856.2 Ų56.215%0.14933%0.333CS..Hα-helixtrans-62.8-41.7178.200000112.9P142 S184 I185 E186P142-A188 WeakPolarHBondContact O-CB 3.42Å; S184-A188 WeakPolarHBondContact O-CB 3.35Å; S184-A188 PolarHBondContact O-N 3.42Å; I185-A188 PolarHBondContact O-N 3.22Å; E186-A188 VanDerWaalsContact C-N 3.34Å; E186-A188 PolarHBondContact O-N 3.31Å
189A97.9Very high92.1Very high0 Ų054.1 Ų54.10%033%0.334CS..Hα-helixtrans-68.1-43.2178.300000111.9A150 L160 L163 I185 E186 A187 A191 L192A150-A189 HydrophobicContact CB-CB 4.39Å; L160-A189 HydrophobicContact CD1-CB 3.91Å; L163-A189 HydrophobicContact CD2-CB 3.72Å; I185-A189 WeakPolarHBondContact O-CB 3.43Å; I185-A189 PolarHBondContact O-N 2.79Å; E186-A189 PolarHBondContact O-N 2.91Å; A187-A189 PolarHBondContact O-N 3.49Å; A189-A191 VanDerWaalsContact C-N 3.35Å; A189-A191 PolarHBondContact O-N 3.21Å; A189-L192 PolarHBondContact O-N 3.1Å
190L97.8Very high90.1Very high77 Ų7764 Ų6440%0.40338%0.38SS..Hα-helixtrans-67.4-33.7179.6-73177.3000112.7L164 E186 A187 L192 V193 P194L164-L190 HydrophobicContact CD2-CD1 4.31Å; L164-L190 HydrophobicContact CD2-CD2 4.07Å; L164-L190 HydrophobicContact CD2-CG 4.35Å; E186-L190 HydrophobicContact CG-CD1 3.89Å; E186-L190 HydrophobicContact CG-CG 4.35Å; E186-L190 WeakPolarHBondContact O-CB 3.44Å; E186-L190 WeakPolarHBondContact O-CG 3.42Å; E186-L190 PolarHBondContact O-N 3.12Å; A187-L190 PolarHBondContact O-N 3.12Å; L190-L192 PolarHBondContact O-N 3.11Å; L190-L192 VanDerWaalsContact O-N 3.14Å; L190-V193 HydrophobicContact CD2-CG2 4.23Å; L190-V193 WeakPolarHBondContact O-CB 3.39Å; L190-V193 PolarHBondContact O-N 3.07Å; L190-V193 VanDerWaalsContact O-N 3.12Å; L190-P194 WeakPolarHBondContact O-CD 3.48Å
191A97Very high89.7Confident61 Ų6163.1 Ų63.150%0.50437%0.372SS..Hα-helixtrans-59.3-24.1174.800000113A187 A189 Y195A187-A191 WeakPolarHBondContact O-CB 3.34Å; A187-A191 PolarHBondContact O-N 3.14Å; A189-A191 VanDerWaalsContact C-N 3.35Å; A189-A191 PolarHBondContact O-N 3.21Å; A191-Y195 WeakPolarHBondContact O-CD2 3.48Å; A191-Y195 WeakPolarHBondContact O-CE2 3.46Å
192L94.3Very high89.2Confident49 Ų4964.9 Ų64.926%0.25739%0.385SS..Hα-helixtrans-86.8-20.8179.1-64.3170.3000113.6H147 A150 A189 L190 Y195 L196H147-L192 HydrophobicContact CB-CD1 3.72Å; A150-L192 HydrophobicContact CB-CB 4.28Å; A150-L192 HydrophobicContact CB-CD1 4.2Å; A189-L192 PolarHBondContact O-N 3.1Å; L190-L192 PolarHBondContact O-N 3.11Å; L190-L192 VanDerWaalsContact O-N 3.14Å; L192-Y195 PolarHBondContact O-N 3.12Å; L192-Y195 VanDerWaalsContact O-N 3.12Å; L192-L196 HydrophobicContact CB-CD1 4.44Å; L192-L196 WeakPolarHBondContact O-CG 3.41Å; L192-L196 PolarHBondContact O-N 3.28Å; L192-L196 VanDerWaalsContact O-N 3.1Å
193V90.4Very high88.7Confident39 Ų3968.4 Ų68.424%0.23641%0.406CS..Hα-helixtrans-56.4-45.5-173.8173.50000113L160 L190 Y195 L196 L197L160-V193 HydrophobicContact CD2-CG2 3.83Å; L190-V193 HydrophobicContact CD2-CG2 4.23Å; L190-V193 WeakPolarHBondContact O-CB 3.39Å; L190-V193 PolarHBondContact O-N 3.07Å; L190-V193 VanDerWaalsContact O-N 3.12Å; V193-Y195 VanDerWaalsContact C-N 3.27Å; V193-Y195 PolarHBondContact O-N 3.01Å; V193-L196 PolarHBondContact O-N 3.5Å; V193-L197 HydrophobicContact CG1-CD1 3.75Å; V193-L197 HydrophobicContact CG1-CG 4.2Å; V193-L197 WeakPolarHBondContact O-CG 3.46Å; V193-L197 PolarHBondContact O-N 3.29Å
194P90.7Very high88.2Confident87 Ų8769.4 Ų69.457%0.56542%0.416SS*.Hα-helixtrans-58.9-38.1178.6-24.835.3000113.2L190 G198L190-P194 WeakPolarHBondContact O-CD 3.48Å; P194-G198 PolarHBondContact O-N 3.07Å
195Y87.8Confident87.5Confident177 Ų17770.9 Ų70.969%0.69442%0.422SS*.Hα-helixtrans-71.4-36.7179.6-58.2-80.4000112A191 L192 V193 G198 A199A191-Y195 WeakPolarHBondContact O-CD2 3.48Å; A191-Y195 WeakPolarHBondContact O-CE2 3.46Å; L192-Y195 PolarHBondContact O-N 3.12Å; L192-Y195 VanDerWaalsContact O-N 3.12Å; V193-Y195 VanDerWaalsContact C-N 3.27Å; V193-Y195 PolarHBondContact O-N 3.01Å; Y195-G198 PolarHBondContact O-N 3.39Å; Y195-A199 WeakPolarHBondContact O-CB 3.42Å; Y195-A199 PolarHBondContact O-N 3.12Å
196L83.8Confident86.7Confident65 Ų6575.7 Ų75.734%0.3445%0.451SS..Hα-helixtrans-70.8-35.2177.9-66.1174.4000112.3A150 T151 L192 V193A150-L196 HydrophobicContact CB-CD1 3.94Å; T151-L196 HydrophobicContact CG2-CD1 4.2Å; T151-L196 HydrophobicContact CG2-CD2 4.07Å; L192-L196 HydrophobicContact CB-CD1 4.44Å; L192-L196 WeakPolarHBondContact O-CG 3.41Å; L192-L196 PolarHBondContact O-N 3.28Å; L192-L196 VanDerWaalsContact O-N 3.1Å; V193-L196 PolarHBondContact O-N 3.5Å
197L80.8Confident85.9Confident114 Ų11480.4 Ų80.460%0.59748%0.479SS*.Hα-helixtrans-75.2-29.9175.8-67.1175.7000112.7V193 A199V193-L197 HydrophobicContact CG1-CD1 3.75Å; V193-L197 HydrophobicContact CG1-CG 4.2Å; V193-L197 WeakPolarHBondContact O-CG 3.46Å; V193-L197 PolarHBondContact O-N 3.29Å; L197-A199 VanDerWaalsContact C-N 3.33Å
198G70.2Confident84.9Confident69 Ų6981.7 Ų81.771%0.71148%0.476SS*.THydrogen-bonded Turntrans-81-8176.300000115P194 Y195P194-G198 PolarHBondContact O-N 3.07Å; Y195-G198 PolarHBondContact O-N 3.39Å
199A61.4Low83.8Confident85 Ų8587 Ų8770%0.70250%0.504SS*.THydrogen-bonded Turntrans-98.92.5179.500000113.8Y195 L197Y195-A199 WeakPolarHBondContact O-CB 3.42Å; Y195-A199 PolarHBondContact O-N 3.12Å; L197-A199 VanDerWaalsContact C-N 3.33Å
200Q53.7Low82.5Confident221 Ų22194.9 Ų94.9100%1.03355%0.549SS*.  trans-97.10173.5-66.6-173.55.900110.8

Retrieved 200 of 200 residues in 175.8 ms (Link to these results)