A0A061ACQ8_CAEEL Loading...

E3 ubiquitin-protein ligase

AlphaFold DB , UniProt , Accession A0A061ACQ8, Species CAEEL (Caenorhabditis elegans), Gene n/a, Length 724 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M30.8Very low66.8Low202 Ų20295.1 Ų95.1100%0.99553%0.531SS*.  0117.30-94.9176.816100108V3M1-V3 VanDerWaalsContact C-N 3.31Å; M1-V3 PolarHBondContact O-N 2.92Å
2V29.5Very low67.9Low131 Ų13194.5 Ų94.579%0.79454%0.535SS*.  trans-60.3108.5150177.60000103.6Q4V2-Q4 PolarHBondContact O-N 3.42Å
3V30.1Very low68.7Low120 Ų12099 Ų9973%0.72756%0.556SS**  trans-60.998.7169.41800000103.9M1 T5M1-V3 VanDerWaalsContact C-N 3.31Å; M1-V3 PolarHBondContact O-N 2.92Å; V3-T5 PolarHBondContact O-N 3.39Å
4Q38.4Very low69.4Low171 Ų17194.4 Ų94.480%0.79953%0.531SS*.  trans-56.8111.3171.8-83.4-173.9-15.200104.8V2 V6V2-Q4 PolarHBondContact O-N 3.42Å; Q4-V6 PolarHBondContact O-N 2.81Å
5T64.6Low69.9Low87 Ų8799.4 Ų99.453%0.53456%0.557SS.*  trans-62.9112.4173.2-57.20000105.1V3 V7V3-T5 PolarHBondContact O-N 3.39Å; T5-V7 PolarHBondContact O-N 3.11Å; T5-V7 VanDerWaalsContact O-N 3.15Å
6V85.7Confident70.3Confident100 Ų10098.5 Ų98.561%0.60655%0.55SS**  trans-58.7121.5177.2-179.30000107.3Q4Q4-V6 PolarHBondContact O-N 2.81Å
7V89.8Confident71.1Confident57 Ų57103.8 Ų103.835%0.34557%0.57SS.*EExtended strand (participates in β ladder)trans-102.9110.7176.7-179.90000107.6T5 L20 T77 R79T5-V7 PolarHBondContact O-N 3.11Å; T5-V7 VanDerWaalsContact O-N 3.15Å; V7-L20 HydrophobicContact CG1-CD2 3.63Å; V7-T77 WeakPolarHBondContact CA-O 3.43Å; V7-T77 HydrophobicContact CG2-CG2 4.24Å; V7-R79 HydrophobicContact CG1-CB 3.98Å
8H94.1Very high72.2Confident40 Ų40100.4 Ų100.419%0.18555%0.553CS.*EExtended strand (participates in β ladder)trans-82.8176.6176.3-63.1-76.5000111.2D57 V59 T77 F78 R79H8-D57 VanDerWaalsContact CA-OD2 3.31Å; H8-D57 WeakPolarHBondContact CA-OD2 3.48Å; H8-D57 VanDerWaalsContact CB-OD2 3.24Å; H8-D57 WeakPolarHBondContact CB-OD2 3.2Å; H8-D57 IonicContact CG-OD2 3.92Å; H8-D57 IonicContact ND1-OD2 3.6Å; H8-V59 HydrophobicContact CB-CG2 4.23Å; H8-V59 WeakPolarHBondContact CE1-CG2 3.2Å; H8-V59 WeakPolarHBondContact ND1-CG2 2.89Å; H8-T77 PolarHBondContact N-O 3.26Å; H8-F78 HydrophobicContact CB-CD1 3.39Å; H8-F78 HydrophobicContact CB-CD2 4.44Å; H8-F78 HydrophobicContact CB-CE1 3.41Å; H8-F78 VanDerWaalsContact CB-CE1 3.41Å; H8-F78 HydrophobicContact CB-CE2 4.46Å; H8-F78 HydrophobicContact CB-CG 3.94Å; H8-F78 HydrophobicContact CB-CZ 3.98Å; H8-F78 CarbonylContact O-C 3.57Å; H8-F78 VanDerWaalsContact O-CA 3.31Å; H8-F78 WeakPolarHBondContact O-CA 3.27Å; H8-R79 PolarHBondContact O-N 3.3Å
9G93.1Very high73.3Confident16 Ų1699.2 Ų99.217%0.16554%0.543CS..EExtended strand (participates in β ladder)trans84-143.7176.600000113.1D57G9-D57 PolarHBondContact N-OD2 3.21Å
10Y91.9Very high74.3Confident39 Ų3996.9 Ų96.915%0.15353%0.53CS..SBendtrans-61.4144.1-174.8-75.9-80.8000112.5T14 T18 V56 R79 T81Y10-T14 HydrophobicContact CD1-CG2 4.43Å; Y10-T14 HydrophobicContact CG-CG2 4.38Å; Y10-T18 HydrophobicContact CD2-CG2 4.29Å; Y10-T18 HydrophobicContact CG-CG2 4.32Å; Y10-V56 HydrophobicContact CD1-CG1 4.17Å; Y10-V56 HydrophobicContact CD2-CG1 4.02Å; Y10-V56 HydrophobicContact CE1-CG1 4.06Å; Y10-V56 HydrophobicContact CE2-CG1 3.91Å; Y10-V56 HydrophobicContact CE2-CG2 4.2Å; Y10-V56 HydrophobicContact CG-CG1 4.14Å; Y10-R79 PolarHBondContact N-O 3.37Å; Y10-R79 WeakPolarHBondContact O-CB 3.17Å; Y10-R79 VanDerWaalsContact O-CD 3.26Å; Y10-R79 WeakPolarHBondContact O-CD 3.37Å; Y10-R79 PolarHBondContact O-NH1 3.4Å; Y10-T81 HydrophobicContact CD2-CG2 4.21Å; Y10-T81 HydrophobicContact CE2-CG2 3.85Å
11P87Confident75.2Confident83 Ų8392.3 Ų92.354%0.53950%0.504SS..  trans-63.6154.9171.727.9-34.2000110.7N13 T14P11-N13 PolarHBondContact O-N 2.8Å; P11-T14 WeakPolarHBondContact O-CG2 3.45Å; P11-T14 PolarHBondContact O-N 3.11Å
12P79.5Confident78.3Confident88 Ų8886.6 Ų86.657%0.57147%0.472SS*.THydrogen-bonded Turntrans-61.7-26-17721.2-30.4000113.6R79P12-R79 VanDerWaalsContact CA-CZ 3.42Å; P12-R79 VanDerWaalsContact CD-NH1 3.34Å
13N78.3Confident81.4Confident153 Ų15380.4 Ų80.482%0.81843%0.434SS*.THydrogen-bonded Turntrans-99.829.5-176-59.3-12.4000112.4P11P11-N13 PolarHBondContact O-N 2.8Å
14T78.4Confident84.5Confident34 Ų3478.9 Ų78.921%0.20942%0.415CS..  trans-76.1143.8174.1-171.60000110.6Y10 P11 N16 T18Y10-T14 HydrophobicContact CD1-CG2 4.43Å; Y10-T14 HydrophobicContact CG-CG2 4.38Å; P11-T14 WeakPolarHBondContact O-CG2 3.45Å; P11-T14 PolarHBondContact O-N 3.11Å; T14-N16 HydrophobicContact CG2-CB 4.31Å; T14-N16 PolarHBondContact O-N 3.2Å; T14-T18 HydrophobicContact CG2-CG2 3.54Å
15D77.2Confident87.3Confident170 Ų17070.8 Ų70.891%0.90938%0.377SS*.SBendtrans-66.8-11.9177.2-64.9-39000113.3
16N76.7Confident88.7Confident85 Ų8568.6 Ų68.646%0.45536%0.362SS..SBendtrans-84.4143.1-178-63.8-45.2000112.1T14 T18 T81T14-N16 HydrophobicContact CG2-CB 4.31Å; T14-N16 PolarHBondContact O-N 3.2Å; N16-T18 HydrophobicContact CB-CG2 4.49Å; N16-T18 PolarHBondContact O-N 3.06Å; N16-T18 VanDerWaalsContact O-N 3.11Å; N16-T81 HydrophobicContact CB-CG2 3.81Å
17E84.1Confident89.2Confident188 Ų18868.2 Ų68.288%0.87935%0.35SS*.  trans-60.6116.1165.1-72.9-174169.300109.6
18T91.1Very high89.4Confident44 Ų4465.5 Ų65.527%0.2733%0.334SS..  trans-123.6149.7-177.851.80000111.8Y10 T14 N16 R79 V80 T81Y10-T18 HydrophobicContact CD2-CG2 4.29Å; Y10-T18 HydrophobicContact CG-CG2 4.32Å; T14-T18 HydrophobicContact CG2-CG2 3.54Å; N16-T18 HydrophobicContact CB-CG2 4.49Å; N16-T18 PolarHBondContact O-N 3.06Å; N16-T18 VanDerWaalsContact O-N 3.11Å; T18-R79 HydrophobicContact CG2-CG 3.97Å; T18-R79 WeakPolarHBondContact OG1-CD 3.23Å; T18-V80 CarbonylContact C-O 3.58Å; T18-V80 VanDerWaalsContact CA-O 3.29Å; T18-V80 WeakPolarHBondContact CA-O 3.17Å; T18-T81 HydrophobicContact CG2-CG2 3.88Å
19E91.8Very high89.3Confident76 Ų7664.3 Ų64.336%0.35533%0.329SS..EExtended strand (participates in β ladder)trans-125.5158.6175.9-67.8174.4-106.500109.6R79 V80 R82 F146E19-R79 WeakPolarHBondContact O-CA 3.22Å; E19-V80 PolarHBondContact N-O 2.89Å; E19-V80 PolarHBondContact O-N 2.87Å; E19-R82 IonicContact OE1-CZ 2.73Å; E19-R82 IonicContact OE1-NE 3.2Å; E19-R82 PolarHBondContact OE1-NE 3.05Å; E19-R82 IonicContact OE1-NH2 3.82Å; E19-R82 PolarHBondContact OE1-NH2 2.95Å; E19-R82 IonicContact OE2-CZ 2.99Å; E19-R82 IonicContact OE2-NE 2.92Å; E19-R82 IonicContact OE2-NH2 2.67Å; E19-R82 PolarHBondContact OE2-NH2 3.03Å; E19-F146 HydrophobicContact CB-CD1 3.8Å; E19-F146 HydrophobicContact CB-CE1 4.03Å
20L93.8Very high89Confident54 Ų5470.8 Ų70.828%0.28335%0.353SS..EExtended strand (participates in β ladder)trans-90.6120.2173.5-64.3-179.1000109.9V7 T77 F78 R79 F146 M147V7-L20 HydrophobicContact CG1-CD2 3.63Å; L20-T77 HydrophobicContact CB-CG2 4.25Å; L20-T77 HydrophobicContact CD2-CG2 4.33Å; L20-F78 CarbonylContact C-O 3.44Å; L20-F78 WeakPolarHBondContact CA-O 3.27Å; L20-R79 HydrophobicContact CD2-CB 4Å; L20-R79 HydrophobicContact CD2-CG 4.42Å; L20-F146 CarbonylContact O-C 3.44Å; L20-F146 WeakPolarHBondContact O-CA 3.42Å; L20-M147 HydrophobicContact CB-CB 4.1Å; L20-M147 HydrophobicContact CB-CG 4.35Å; L20-M147 HydrophobicContact CB-SD 4.29Å; L20-M147 HydrophobicContact CD1-SD 4.47Å; L20-M147 PolarHBondContact O-N 3.36Å
21L94.7Very high88.7Confident0 Ų068.9 Ų68.90%035%0.345CS..EExtended strand (participates in β ladder)trans-103.5123.5174.1-178.873.7000109.5V23 T77 F78 V80 M86 L109 I114 F144 F146L21-V23 HydrophobicContact CD2-CG2 4.03Å; L21-V23 HydrophobicContact CG-CG2 4.21Å; L21-T77 CarbonylContact O-C 3.55Å; L21-T77 WeakPolarHBondContact O-CA 3.18Å; L21-F78 PolarHBondContact N-O 2.83Å; L21-F78 PolarHBondContact O-N 3.21Å; L21-V80 HydrophobicContact CB-CG1 4.14Å; L21-V80 HydrophobicContact CB-CG2 3.77Å; L21-V80 HydrophobicContact CD2-CG1 4.33Å; L21-M86 HydrophobicContact CD2-CE 4.17Å; L21-L109 HydrophobicContact CD2-CD1 3.97Å; L21-L109 HydrophobicContact CD2-CD2 3.68Å; L21-I114 HydrophobicContact CD1-CG2 4.02Å; L21-F144 HydrophobicContact CD1-CB 4.31Å; L21-F144 HydrophobicContact CD2-CD1 4.41Å; L21-F146 HydrophobicContact CB-CD1 4.35Å; L21-F146 HydrophobicContact CB-CE1 4.17Å; L21-F146 HydrophobicContact CD1-CD1 4.15Å; L21-F146 HydrophobicContact CD1-CD2 4.38Å; L21-F146 HydrophobicContact CD1-CE1 3.97Å; L21-F146 HydrophobicContact CD1-CE2 4.18Å; L21-F146 HydrophobicContact CD1-CG 4.36Å; L21-F146 HydrophobicContact CD1-CZ 3.99Å
22R94.3Very high87.8Confident83 Ų8365.8 Ų65.831%0.31333%0.328SS..EExtended strand (participates in β ladder)trans-95.3122.8171.9-173.3174.2-80.2174.4-5.1110.1V75 F76 F144 H145 M147R22-V75 HydrophobicContact CG-CG1 3.45Å; R22-V75 VanDerWaalsContact CG-CG1 3.45Å; R22-F76 CarbonylContact C-O 3.55Å; R22-F76 WeakPolarHBondContact CA-O 3.44Å; R22-F144 WeakPolarHBondContact O-CA 3.18Å; R22-H145 WeakPolarHBondContact CD-CE1 3.45Å; R22-H145 PolarHBondContact N-O 3.13Å; R22-H145 PolarHBondContact O-N 2.93Å; R22-H145 VanDerWaalsContact O-N 3.12Å; R22-M147 HydrophobicContact CB-CG 4.32Å
23V95.6Very high86.5Confident0 Ų068.4 Ų68.40%033%0.33CS..EExtended strand (participates in β ladder)trans-110.1117.7178.9-174.70000108.7L21 V75 F76 F78 M86 F144L21-V23 HydrophobicContact CD2-CG2 4.03Å; L21-V23 HydrophobicContact CG-CG2 4.21Å; V23-V75 WeakPolarHBondContact O-CA 3.38Å; V23-F76 PolarHBondContact N-O 2.92Å; V23-F76 PolarHBondContact O-N 2.84Å; V23-F78 HydrophobicContact CG2-CD2 4.04Å; V23-F78 HydrophobicContact CG2-CE2 4.42Å; V23-M86 HydrophobicContact CG2-CE 4.22Å; V23-F144 HydrophobicContact CB-CD1 4.47Å; V23-F144 HydrophobicContact CB-CE1 4.47Å; V23-F144 HydrophobicContact CG1-CD1 4.13Å; V23-F144 HydrophobicContact CG1-CE1 3.72Å; V23-F144 HydrophobicContact CG1-CZ 4.44Å; V23-F144 HydrophobicContact CG2-CD1 3.92Å; V23-F144 HydrophobicContact CG2-CE1 4.08Å
24R95.1Very high85.1Confident89 Ų8967.3 Ų67.334%0.33632%0.315SS..EExtended strand (participates in β ladder)trans-102.8121172.6-173.3172.7-176.3177.63.3109.6N73 S74 V75 L142 S143R24-N73 PolarHBondContact NH2-OD1 3.24Å; R24-S74 WeakPolarHBondContact CA-O 3.32Å; R24-V75 HydrophobicContact CB-CG2 4.29Å; R24-V75 HydrophobicContact CG-CG2 3.93Å; R24-L142 VanDerWaalsContact O-CA 3.3Å; R24-L142 WeakPolarHBondContact O-CA 3.27Å; R24-S143 WeakPolarHBondContact CB-OG 3.46Å; R24-S143 PolarHBondContact N-O 2.65Å; R24-S143 PolarHBondContact O-N 3.48Å; R24-S143 VanDerWaalsContact O-N 3.1Å
25L96.6Very high83.4Confident0 Ų068.8 Ų68.80%032%0.321CS..EExtended strand (participates in β ladder)trans-101.7102.6170.3173.163000108.5C44 V61 W72 N73 S74 F76 L140 L142L25-C44 HydrophobicContact CD2-CB 3.69Å; L25-V61 HydrophobicContact CD2-CB 4.34Å; L25-V61 HydrophobicContact CD2-CG1 4.05Å; L25-V61 HydrophobicContact CD2-CG2 3.91Å; L25-W72 HydrophobicContact CD1-CE3 3.8Å; L25-W72 HydrophobicContact CD1-CZ3 4.06Å; L25-W72 HydrophobicContact CD2-CB 4.12Å; L25-W72 HydrophobicContact CD2-CD2 3.85Å; L25-W72 HydrophobicContact CD2-CE3 3.9Å; L25-W72 HydrophobicContact CD2-CG 3.96Å; L25-W72 HydrophobicContact CG-CB 4.11Å; L25-W72 HydrophobicContact CG-CD2 4.15Å; L25-W72 HydrophobicContact CG-CE3 3.79Å; L25-W72 HydrophobicContact CG-CG 4.31Å; L25-N73 CarbonylContact O-C 3.49Å; L25-N73 WeakPolarHBondContact O-CA 3.39Å; L25-N73 PolarHBondContact O-N 2.9Å; L25-N73 VanDerWaalsContact O-N 3.12Å; L25-S74 PolarHBondContact N-O 3.09Å; L25-S74 PolarHBondContact O-N 2.82Å; L25-F76 HydrophobicContact CB-CE2 4.49Å; L25-L140 HydrophobicContact CD1-CD2 4.41Å; L25-L142 HydrophobicContact CB-CD2 4.2Å; L25-L142 HydrophobicContact CD1-CD2 3.39Å; L25-L142 HydrophobicContact CG-CD2 4.39Å
26L94.8Very high81.9Confident41 Ų4164 Ų6422%0.21530%0.296CS..EExtended strand (participates in β ladder)trans-82.1-64.6-178.7-177.965.4000111.1W72 N73 P121 F141L26-W72 PolarHBondContact O-N 2.66Å; L26-N73 HydrophobicContact CD1-CB 4.28Å; L26-N73 WeakPolarHBondContact CD1-OD1 3.48Å; L26-N73 PolarHBondContact O-N 2.69Å; L26-P121 HydrophobicContact CB-CB 4.15Å; L26-P121 HydrophobicContact CB-CG 4.16Å; L26-P121 HydrophobicContact CD2-CB 4.11Å; L26-P121 HydrophobicContact CD2-CG 4.1Å; L26-F141 HydrophobicContact CB-CB 4.12Å; L26-F141 WeakPolarHBondContact CB-O 3.36Å; L26-F141 HydrophobicContact CD2-CB 4.34Å; L26-F141 PolarHBondContact N-O 3.32Å
27R95.8Very high80.5Confident93 Ų9362 Ų6235%0.35128%0.284SS..EExtended strand (participates in β ladder)trans-160.5159.7-172.464179.4-175.9130.64.4112.6P70 F141R27-P70 CarbonylContact C-O 3.45Å; R27-P70 WeakPolarHBondContact CA-O 3.32Å; R27-P70 WeakPolarHBondContact CB-O 3.27Å; R27-F141 HydrophobicContact CG-CB 3.92Å; R27-F141 HydrophobicContact CG-CD2 3.85Å; R27-F141 HydrophobicContact CG-CG 4.03Å; R27-F141 VanDerWaalsContact NH2-CZ 3.31Å; R27-F141 PolarHBondContact O-N 3.4Å
28G93.9Very high78.9Confident0 Ų055.1 Ų55.10%026%0.264CS..EExtended strand (participates in β ladder)trans-99154.1164.300000110.9N69 P70 S139G28-N69 CarbonylContact O-C 3.58Å; G28-N69 WeakPolarHBondContact O-CA 3.39Å; G28-P70 PolarHBondContact N-O 3.37Å; G28-S139 CarbonylContact C-O 3.45Å; G28-S139 WeakPolarHBondContact CA-O 3.42Å
29T91.7Very high77.5Confident15 Ų1556.8 Ų56.89%0.09227%0.274CS..EExtended strand (participates in β ladder)trans-137.2141.1173.261.60000111L31 N69 G138 S139 F141T29-L31 PolarHBondContact O-N 3.49Å; T29-L31 VanDerWaalsContact O-N 3.1Å; T29-N69 WeakPolarHBondContact CA-OD1 3.45Å; T29-G138 CarbonylContact O-C 3.58Å; T29-G138 VanDerWaalsContact O-CA 3.23Å; T29-G138 WeakPolarHBondContact O-CA 3.18Å; T29-S139 PolarHBondContact N-O 2.93Å; T29-S139 PolarHBondContact O-N 3.18Å; T29-F141 HydrophobicContact CG2-CD2 3.95Å; T29-F141 HydrophobicContact CG2-CE2 3.49Å; T29-F141 VanDerWaalsContact CG2-CE2 3.49Å
30K86.4Confident76.8Confident151 Ų15153.5 Ų53.566%0.65726%0.259SS*.SBendtrans51.434.1176.6-59.1179-180172.90113.6G32 R68 N69 G138K30-G32 PolarHBondContact O-N 3.41Å; K30-R68 PolarHBondContact N-O 2.69Å; K30-N69 PolarHBondContact N-OD1 3.13Å; K30-G138 WeakPolarHBondContact O-CA 3.43Å; K30-G138 PolarHBondContact O-N 2.84Å
31L85.1Confident76.4Confident0 Ų052 Ų520%025%0.253CS..  trans-52133.6178.3-60.9-179.3000110T29 P42 R68 P70 V90 M102 L126T29-L31 PolarHBondContact O-N 3.49Å; T29-L31 VanDerWaalsContact O-N 3.1Å; L31-P42 HydrophobicContact CD1-CB 3.71Å; L31-P42 HydrophobicContact CD1-CG 3.91Å; L31-R68 PolarHBondContact N-O 2.83Å; L31-R68 PolarHBondContact O-NE 2.83Å; L31-R68 PolarHBondContact O-NH2 2.77Å; L31-P70 HydrophobicContact CD1-CG 3.66Å; L31-V90 HydrophobicContact CD1-CG1 4.03Å; L31-V90 HydrophobicContact CD2-CG1 4.33Å; L31-M102 HydrophobicContact CB-CE 3.76Å; L31-L126 HydrophobicContact CD2-CD1 3.48Å; L31-L126 VanDerWaalsContact CD2-CD1 3.48Å
32G68.6Low76.2Confident17 Ų1752 Ų5218%0.17525%0.253CS..  trans-62.9144-163.600000114K30 R34 M102 I137K30-G32 PolarHBondContact O-N 3.41Å; G32-R34 PolarHBondContact O-N 3Å; G32-M102 VanDerWaalsContact O-CE 3.25Å; G32-M102 WeakPolarHBondContact O-CE 3.3Å; G32-I137 PolarHBondContact N-O 2.92Å
33K51.7Low76.3Confident143 Ų14348.6 Ų48.662%0.62224%0.241SC*.  trans-76.1110168.8-77.3-174.3170.4-168.70109.4
34R49.1Very low76.3Confident131 Ų13148.6 Ų48.649%0.49424%0.241SC..SBendtrans-104.1-46.4153.2-80.7-167.4178.3-172.1-1.4110.5G32 L36 T130G32-R34 PolarHBondContact O-N 3Å; R34-L36 PolarHBondContact O-N 2.87Å; R34-T130 PolarHBondContact NH2-OG1 2.83Å
35D44.3Very low76.4Confident64 Ų6445.2 Ų45.234%0.34223%0.229SC..  trans-82.4120.5173.8-63.6-10.1000109.3L37D35-L37 PolarHBondContact O-N 3.07Å
36L44.2Very low76.4Confident71 Ų7145.2 Ų45.237%0.37223%0.229SC..SBendtrans-71.2-4.8176.5-125.5115.5000112.5R34 Y405 R406 Y481R34-L36 PolarHBondContact O-N 2.87Å; L36-Y405 HydrophobicContact CD2-CD1 3.97Å; L36-Y405 HydrophobicContact CD2-CE1 3.65Å; L36-R406 HydrophobicContact CD1-CG 4Å; L36-Y481 PolarHBondContact O-OH 3.35Å
37L47.2Very low76.5Confident41 Ų4145.9 Ų45.922%0.21523%0.229CC..SBendtrans-117.1-13.5-158.7-81.7153.3000115.8D35 F401 E402 Y452 Y481D35-L37 PolarHBondContact O-N 3.07Å; L37-F401 HydrophobicContact CD1-CD1 4.05Å; L37-F401 HydrophobicContact CD1-CE1 4.26Å; L37-F401 HydrophobicContact CD2-CE1 4.28Å; L37-E402 HydrophobicContact CD1-CG 3.8Å; L37-E402 WeakPolarHBondContact CD1-OE1 3.42Å; L37-Y452 HydrophobicContact CD1-CD1 4.07Å; L37-Y452 HydrophobicContact CD1-CE1 3.47Å; L37-Y452 VanDerWaalsContact CD1-CE1 3.47Å; L37-Y452 HydrophobicContact CD2-CD1 4.01Å; L37-Y452 HydrophobicContact CD2-CE1 4.26Å; L37-Y452 HydrophobicContact CG-CE1 4.44Å; L37-Y481 HydrophobicContact CD2-CD1 4.22Å; L37-Y481 HydrophobicContact CD2-CD2 4.35Å; L37-Y481 HydrophobicContact CD2-CE1 3.47Å; L37-Y481 VanDerWaalsContact CD2-CE1 3.47Å; L37-Y481 HydrophobicContact CD2-CE2 3.62Å; L37-Y481 WeakPolarHBondContact CD2-OH 3.41Å; L37-Y481 HydrophobicContact CG-CE1 4.19Å; L37-Y481 VanDerWaalsContact CG-OH 3.25Å; L37-Y481 WeakPolarHBondContact CG-OH 3.37Å
38G51.8Low76.6Confident44 Ų4441.5 Ų41.545%0.45421%0.212SC..  trans-130.9135.9-169.600000111C40G38-C40 PolarHBondContact O-N 3.11Å; G38-C40 VanDerWaalsContact O-N 3.12Å
39V61.4Low76.7Confident79 Ų7942.2 Ų42.248%0.47922%0.215SC..  trans-65111.1149.8-153.90000104.8K66 R68V39-K66 HydrophobicContact CB-CB 3.88Å; V39-K66 HydrophobicContact CB-CG 4.49Å; V39-K66 HydrophobicContact CG1-CB 4.35Å; V39-K66 WeakPolarHBondContact CG1-O 3.46Å; V39-K66 WeakPolarHBondContact O-CA 3.37Å; V39-R68 HydrophobicContact CG1-CG 4.44Å
40C75.9Confident76.7Confident7 Ų743 Ų435%0.04722%0.219CC..  trans-52.1149.9-178.952.90000110.8G38 P42 K66 T67 D92 M102G38-C40 PolarHBondContact O-N 3.11Å; G38-C40 VanDerWaalsContact O-N 3.12Å; C40-P42 WeakPolarHBondContact O-CD 3.46Å; C40-K66 CarbonylContact O-C 3.55Å; C40-K66 VanDerWaalsContact O-CA 3.26Å; C40-K66 WeakPolarHBondContact O-CA 3.4Å; C40-K66 PolarHBondContact O-N 2.74Å; C40-T67 PolarHBondContact O-N 3.48Å; C40-T67 PolarHBondContact SG-O 2.76Å; C40-D92 WeakPolarHBondContact CA-OD1 3.32Å; C40-D92 WeakPolarHBondContact CB-OD1 3.32Å; C40-D92 VanDerWaalsContact CB-OD2 3.24Å; C40-D92 WeakPolarHBondContact CB-OD2 3.41Å; C40-M102 HydrophobicContact CB-CE 4.16Å; C40-M102 HydrophobicContact CB-SD 4.48Å
41S86.2Confident76.7Confident22 Ų2240.2 Ų40.215%0.15422%0.219CC..  trans-106.175.9169.9-63.40000109T63 K64 K66 D92 E93S41-T63 WeakPolarHBondContact O-CG2 3.16Å; S41-K64 CarbonylContact C-O 3.53Å; S41-K64 VanDerWaalsContact CA-O 3.28Å; S41-K64 WeakPolarHBondContact CA-O 3.46Å; S41-K66 PolarHBondContact OG-N 3.46Å; S41-K66 VanDerWaalsContact OG-N 3.11Å; S41-D92 PolarHBondContact N-OD1 3.49Å; S41-E93 WeakPolarHBondContact O-CB 3.26Å; S41-E93 PolarHBondContact O-N 2.76Å; S41-E93 VanDerWaalsContact O-N 3.09Å
42P91.6Very high76.8Confident0 Ų046.3 Ų46.30%025%0.251CS..EExtended strand (participates in β ladder)trans-72.4141-170.928.9-39.1000112.9L31 C40 K64 T67 P70 W72 V90 Y91 M102L31-P42 HydrophobicContact CD1-CB 3.71Å; L31-P42 HydrophobicContact CD1-CG 3.91Å; C40-P42 WeakPolarHBondContact O-CD 3.46Å; P42-K64 WeakPolarHBondContact CD-O 3.5Å; P42-K64 PolarHBondContact O-N 2.8Å; P42-T67 WeakPolarHBondContact CD-O 3.43Å; P42-T67 HydrophobicContact CG-CG2 4.43Å; P42-T67 VanDerWaalsContact CG-O 3.28Å; P42-T67 WeakPolarHBondContact CG-O 3.16Å; P42-P70 HydrophobicContact CB-CG 4.23Å; P42-P70 HydrophobicContact CG-CB 3.77Å; P42-P70 HydrophobicContact CG-CG 3.53Å; P42-W72 HydrophobicContact CB-CZ2 4.29Å; P42-V90 HydrophobicContact CB-CG1 4.3Å; P42-Y91 WeakPolarHBondContact CA-O 3.24Å; P42-M102 HydrophobicContact CB-SD 4.47Å
43Y94.6Very high77.7Confident12 Ų1247.4 Ų47.45%0.04726%0.263CS..EExtended strand (participates in β ladder)trans-129.9159.6161.872.8-90.9000110.4M45 Q60 Y91 E93 D99Y43-M45 HydrophobicContact CE2-CE 4.25Å; Y43-Q60 HydrophobicContact CD2-CG 3.79Å; Y43-Q60 HydrophobicContact CE2-CG 4.01Å; Y43-Y91 VanDerWaalsContact CE1-CB 3.42Å; Y43-Y91 HydrophobicContact CE1-CG 4.3Å; Y43-Y91 AromaticContact CE2-CD2 3.78Å; Y43-Y91 HydrophobicContact CE2-CD2 3.78Å; Y43-Y91 HydrophobicContact CE2-CG 4.08Å; Y43-Y91 AromaticContact CZ-CD2 3.96Å; Y43-Y91 AromaticContact CZ-CG 3.78Å; Y43-Y91 PolarHBondContact N-O 2.68Å; Y43-Y91 PolarHBondContact O-N 3.11Å; Y43-E93 HydrophobicContact CD1-CB 3.99Å; Y43-E93 HydrophobicContact CE1-CB 4.15Å; Y43-D99 HydrophobicContact CE1-CB 4.27Å; Y43-D99 VanDerWaalsContact CE1-OD2 3.23Å; Y43-D99 WeakPolarHBondContact CE1-OD2 3.26Å; Y43-D99 VanDerWaalsContact CZ-OD2 3.28Å; Y43-D99 PolarHBondContact OH-OD2 3.31Å
44C96.1Very high79.6Confident0 Ų044.9 Ų44.90%026%0.256CS..EExtended strand (participates in β ladder)trans-108.7141.1176.9-71.60000110.1L25 V61 W72 I88 L89L25-C44 HydrophobicContact CD2-CB 3.69Å; C44-V61 HydrophobicContact CB-CB 4.12Å; C44-V61 HydrophobicContact CB-CG2 3.94Å; C44-V61 WeakPolarHBondContact O-CB 3.18Å; C44-V61 WeakPolarHBondContact O-CG2 3.28Å; C44-V61 PolarHBondContact O-N 2.96Å; C44-W72 WeakPolarHBondContact SG-CH2 3.47Å; C44-I88 HydrophobicContact CB-CG2 4.15Å; C44-L89 CarbonylContact C-O 3.6Å; C44-L89 VanDerWaalsContact CA-O 3.22Å; C44-L89 WeakPolarHBondContact CA-O 3.37Å
45M96.5Very high81.8Confident18 Ų1842 Ų429%0.08925%0.253CS..EExtended strand (participates in β ladder)trans-108.8117164.3-170.167.269.300108Y43 E58 V59 Q60 I88 L89 Y91Y43-M45 HydrophobicContact CE2-CE 4.25Å; M45-E58 HydrophobicContact CG-CB 4.47Å; M45-E58 HydrophobicContact SD-CB 4.27Å; M45-E58 HydrophobicContact SD-CG 4.35Å; M45-V59 VanDerWaalsContact SD-C 3.54Å; M45-Q60 HydrophobicContact CE-CB 3.68Å; M45-Q60 HydrophobicContact CE-CG 3.9Å; M45-Q60 HydrophobicContact SD-CB 3.86Å; M45-Q60 PolarHBondContact SD-N 3.45Å; M45-I88 WeakPolarHBondContact O-CA 3.25Å; M45-L89 HydrophobicContact CB-CB 4.27Å; M45-L89 HydrophobicContact CB-CD1 4.34Å; M45-L89 PolarHBondContact N-O 2.98Å; M45-L89 PolarHBondContact O-N 3.24Å; M45-Y91 HydrophobicContact CB-CD2 4.32Å; M45-Y91 HydrophobicContact CB-CE2 3.98Å
46I97.3Very high84Confident0 Ų041 Ų410%025%0.249CC..EExtended strand (participates in β ladder)trans-94.2114.3175.1-54.6177.8000107.5E58 V59 V61 F76 F78 M86 I88I46-E58 CarbonylContact O-C 3.3Å; I46-E58 VanDerWaalsContact O-CA 3.22Å; I46-E58 WeakPolarHBondContact O-CA 3.21Å; I46-V59 PolarHBondContact N-O 3.42Å; I46-V59 PolarHBondContact O-N 3.47Å; I46-V61 HydrophobicContact CD1-CG2 3.98Å; I46-V61 HydrophobicContact CG1-CG2 4.08Å; I46-F76 HydrophobicContact CD1-CD2 3.28Å; I46-F76 HydrophobicContact CD1-CE2 3.42Å; I46-F76 VanDerWaalsContact CD1-CE2 3.42Å; I46-F76 HydrophobicContact CD1-CG 3.88Å; I46-F76 HydrophobicContact CD1-CZ 4.14Å; I46-F78 HydrophobicContact CB-CZ 4.13Å; I46-F78 HydrophobicContact CG2-CE2 3.68Å; I46-F78 HydrophobicContact CG2-CZ 3.55Å; I46-M86 HydrophobicContact CG2-CE 4.48Å; I46-M86 HydrophobicContact CG2-SD 3.45Å; I46-M86 WeakPolarHBondContact CG2-SD 3.3Å; I46-I88 HydrophobicContact CG1-CG1 4.39Å; I46-I88 HydrophobicContact CG1-CG2 4.46Å; I46-I88 HydrophobicContact CG2-CG1 4.47Å
47R97.6Very high86.5Confident56 Ų5640 Ų4021%0.21124%0.244CC..EExtended strand (participates in β ladder)trans-119.3127.9-175.1-177.1178.5-70.3168-0.9111E49 T55 E58 K87 L89R47-E49 HydrophobicContact CG-CG 4.11Å; R47-T55 WeakPolarHBondContact CD-OG1 3.22Å; R47-T55 HydrophobicContact CG-CG2 3.76Å; R47-E58 HydrophobicContact CB-CB 4.28Å; R47-E58 HydrophobicContact CG-CB 4.33Å; R47-E58 IonicContact CZ-OE2 2.64Å; R47-E58 VanDerWaalsContact CZ-OE2 3.29Å; R47-E58 IonicContact NE-OE2 2.82Å; R47-E58 PolarHBondContact NE-OE2 2.91Å; R47-E58 IonicContact NH2-OE2 2.97Å; R47-E58 PolarHBondContact NH2-OE2 3.41Å; R47-K87 HydrophobicContact CB-CB 4.46Å; R47-K87 PolarHBondContact N-O 2.99Å; R47-K87 PolarHBondContact O-N 3.27Å; R47-L89 HydrophobicContact CB-CD1 3.95Å
48L97.1Very high88.8Confident0 Ų042.2 Ų42.20%025%0.253CS..EExtended strand (participates in β ladder)trans-95.7124.1170.6-17967.2000109.1V56 D57 F78 V80 C84 M86L48-V56 HydrophobicContact CB-CB 4.35Å; L48-V56 HydrophobicContact CD2-CB 3.93Å; L48-V56 HydrophobicContact CD2-CG1 3.86Å; L48-V56 HydrophobicContact CG-CB 4.01Å; L48-V56 HydrophobicContact CG-CG1 4.49Å; L48-V56 HydrophobicContact CG-CG2 4.4Å; L48-V56 PolarHBondContact O-N 3.42Å; L48-D57 PolarHBondContact N-O 3.2Å; L48-F78 HydrophobicContact CB-CD1 4.32Å; L48-F78 HydrophobicContact CD2-CD1 4.47Å; L48-V80 HydrophobicContact CD1-CB 4.29Å; L48-V80 HydrophobicContact CD1-CG1 3.6Å; L48-V80 HydrophobicContact CD2-CG1 3.88Å; L48-V80 HydrophobicContact CG-CG1 4.42Å; L48-C84 HydrophobicContact CD1-CB 3.63Å; L48-C84 HydrophobicContact CG-CB 4.47Å; L48-M86 HydrophobicContact CB-CE 4.27Å; L48-M86 HydrophobicContact CD1-CE 3.87Å
49E95.5Very high90.9Very high15 Ų1541 Ų417%0.0724%0.237CC..EExtended strand (participates in β ladder)trans-114.9141.8176.4-67.1176.8-177.400110.8R47 D54 C84 Q85 K87R47-E49 HydrophobicContact CG-CG 4.11Å; E49-D54 CarbonylContact C-O 3.53Å; E49-D54 VanDerWaalsContact CA-O 3.24Å; E49-D54 WeakPolarHBondContact CA-O 3.43Å; E49-C84 CarbonylContact O-C 3.47Å; E49-C84 VanDerWaalsContact O-CA 3.22Å; E49-C84 WeakPolarHBondContact O-CA 3.46Å; E49-C84 VanDerWaalsContact O-CB 3.28Å; E49-C84 WeakPolarHBondContact O-CB 3.5Å; E49-Q85 PolarHBondContact N-O 3.49Å; E49-Q85 PolarHBondContact O-N 3.36Å; E49-K87 WeakPolarHBondContact OE1-CD 3.38Å; E49-K87 IonicContact OE1-NZ 2.64Å; E49-K87 PolarHBondContact OE1-NZ 2.98Å; E49-K87 WeakPolarHBondContact OE2-CE 3.37Å; E49-K87 IonicContact OE2-NZ 3.62Å; E49-K87 PolarHBondContact OE2-NZ 3.18Å
50N91.6Very high92.5Very high31 Ų3142.6 Ų42.617%0.16624%0.239CC..  trans-77.3-179.4173.773.213.2000111.1N52 G53 D54 V56N50-N52 PolarHBondContact O-N 2.84Å; N50-N52 WeakPolarHBondContact OD1-CA 3.28Å; N50-N52 WeakPolarHBondContact OD1-CB 3.11Å; N50-N52 PolarHBondContact OD1-N 3.4Å; N50-G53 PolarHBondContact O-N 3.04Å; N50-G53 VanDerWaalsContact O-N 3.08Å; N50-G53 PolarHBondContact OD1-N 3.5Å; N50-G53 VanDerWaalsContact OD1-N 3.07Å; N50-D54 PolarHBondContact N-O 3.1Å; N50-D54 WeakPolarHBondContact ND2-CB 3.32Å; N50-D54 PolarHBondContact ND2-OD2 3.27Å; N50-D54 PolarHBondContact OD1-N 3.31Å; N50-V56 HydrophobicContact CB-CG2 3.79Å
51S86.8Confident93.4Very high94 Ų9442.6 Ų42.666%0.65724%0.239SC*.THydrogen-bonded Turntrans-63.3-19.9178.554.90000114.9
52N88.2Confident93.6Very high128 Ų12846.4 Ų46.468%0.68425%0.254SS*.THydrogen-bonded Turntrans-87.8-9178.1-57.4-17.3000112.1N50 D54N50-N52 PolarHBondContact O-N 2.84Å; N50-N52 WeakPolarHBondContact OD1-CA 3.28Å; N50-N52 WeakPolarHBondContact OD1-CB 3.11Å; N50-N52 PolarHBondContact OD1-N 3.4Å; N52-D54 WeakPolarHBondContact CB-OD2 3.34Å
53G87.1Confident93.6Very high40 Ų4047.9 Ų47.941%0.41226%0.263SS..SBendtrans87.85.1-173.100000114.2N50N50-G53 PolarHBondContact O-N 3.04Å; N50-G53 VanDerWaalsContact O-N 3.08Å; N50-G53 PolarHBondContact OD1-N 3.5Å; N50-G53 VanDerWaalsContact OD1-N 3.07Å
54D91Very high93.4Very high89 Ų8949.8 Ų49.848%0.47627%0.272SS..  trans-75.3141.9175.3-45.3-54.6000110E49 N50 N52 V56E49-D54 CarbonylContact C-O 3.53Å; E49-D54 VanDerWaalsContact CA-O 3.24Å; E49-D54 WeakPolarHBondContact CA-O 3.43Å; N50-D54 PolarHBondContact N-O 3.1Å; N50-D54 WeakPolarHBondContact ND2-CB 3.32Å; N50-D54 PolarHBondContact ND2-OD2 3.27Å; N50-D54 PolarHBondContact OD1-N 3.31Å; N52-D54 WeakPolarHBondContact CB-OD2 3.34Å; D54-V56 PolarHBondContact O-N 3.47Å
55T94.8Very high92.9Very high70 Ų7056.8 Ų56.843%0.42930%0.302SS..EExtended strand (participates in β ladder)trans-72.4122.5175.5-59.80000110.1R47 E58R47-T55 WeakPolarHBondContact CD-OG1 3.22Å; R47-T55 HydrophobicContact CG-CG2 3.76Å; T55-E58 HydrophobicContact CG2-CB 4.39Å
56V92Very high92.1Very high44 Ų4462.8 Ų62.827%0.26733%0.328SS..EExtended strand (participates in β ladder)trans-85.9-45.1176.1179.20000110.7Y10 L48 N50 D54Y10-V56 HydrophobicContact CD1-CG1 4.17Å; Y10-V56 HydrophobicContact CD2-CG1 4.02Å; Y10-V56 HydrophobicContact CE1-CG1 4.06Å; Y10-V56 HydrophobicContact CE2-CG1 3.91Å; Y10-V56 HydrophobicContact CE2-CG2 4.2Å; Y10-V56 HydrophobicContact CG-CG1 4.14Å; L48-V56 HydrophobicContact CB-CB 4.35Å; L48-V56 HydrophobicContact CD2-CB 3.93Å; L48-V56 HydrophobicContact CD2-CG1 3.86Å; L48-V56 HydrophobicContact CG-CB 4.01Å; L48-V56 HydrophobicContact CG-CG1 4.49Å; L48-V56 HydrophobicContact CG-CG2 4.4Å; L48-V56 PolarHBondContact O-N 3.42Å; N50-V56 HydrophobicContact CB-CG2 3.79Å; D54-V56 PolarHBondContact O-N 3.47Å
57D95.5Very high91.4Very high51 Ų5164.6 Ų64.627%0.27334%0.339SS..EExtended strand (participates in β ladder)trans-160.2156.4176.4-1657.7000109.3H8 G9 L48H8-D57 VanDerWaalsContact CA-OD2 3.31Å; H8-D57 WeakPolarHBondContact CA-OD2 3.48Å; H8-D57 VanDerWaalsContact CB-OD2 3.24Å; H8-D57 WeakPolarHBondContact CB-OD2 3.2Å; H8-D57 IonicContact CG-OD2 3.92Å; H8-D57 IonicContact ND1-OD2 3.6Å; G9-D57 PolarHBondContact N-OD2 3.21Å; L48-D57 PolarHBondContact N-O 3.2Å
58E95.8Very high90.8Very high87 Ų8766.5 Ų66.541%0.40735%0.346SS..EExtended strand (participates in β ladder)trans-144.8147.1174.165177.2-160.300113.2M45 I46 R47 T55M45-E58 HydrophobicContact CG-CB 4.47Å; M45-E58 HydrophobicContact SD-CB 4.27Å; M45-E58 HydrophobicContact SD-CG 4.35Å; I46-E58 CarbonylContact O-C 3.3Å; I46-E58 VanDerWaalsContact O-CA 3.22Å; I46-E58 WeakPolarHBondContact O-CA 3.21Å; R47-E58 HydrophobicContact CB-CB 4.28Å; R47-E58 HydrophobicContact CG-CB 4.33Å; R47-E58 IonicContact CZ-OE2 2.64Å; R47-E58 VanDerWaalsContact CZ-OE2 3.29Å; R47-E58 IonicContact NE-OE2 2.82Å; R47-E58 PolarHBondContact NE-OE2 2.91Å; R47-E58 IonicContact NH2-OE2 2.97Å; R47-E58 PolarHBondContact NH2-OE2 3.41Å; T55-E58 HydrophobicContact CG2-CB 4.39Å
59V95.5Very high90.4Very high18 Ų1870.6 Ų70.611%0.10937%0.368CS..EExtended strand (participates in β ladder)trans-130.6119.3-177.2-175.60000109.7H8 M45 I46 F76 F78H8-V59 HydrophobicContact CB-CG2 4.23Å; H8-V59 WeakPolarHBondContact CE1-CG2 3.2Å; H8-V59 WeakPolarHBondContact ND1-CG2 2.89Å; M45-V59 VanDerWaalsContact SD-C 3.54Å; I46-V59 PolarHBondContact N-O 3.42Å; I46-V59 PolarHBondContact O-N 3.47Å; V59-F76 HydrophobicContact CG1-CD1 3.96Å; V59-F76 HydrophobicContact CG1-CE1 3.72Å; V59-F78 HydrophobicContact CB-CZ 4.36Å; V59-F78 HydrophobicContact CG2-CE1 4.08Å; V59-F78 HydrophobicContact CG2-CZ 3.71Å
60Q95.5Very high90.3Very high113 Ų11370 Ų7053%0.52837%0.365SS..EExtended strand (participates in β ladder)trans-80.6124.5170-170.6172.4-3000110Y43 M45Y43-Q60 HydrophobicContact CD2-CG 3.79Å; Y43-Q60 HydrophobicContact CE2-CG 4.01Å; M45-Q60 HydrophobicContact CE-CB 3.68Å; M45-Q60 HydrophobicContact CE-CG 3.9Å; M45-Q60 HydrophobicContact SD-CB 3.86Å; M45-Q60 PolarHBondContact SD-N 3.45Å
61V94.8Very high90.4Very high6 Ų672.4 Ų72.44%0.03638%0.381CS..PPolyproline II helixtrans-86.2150.1172.6-169.20000109L25 C44 I46 W72 F76L25-V61 HydrophobicContact CD2-CB 4.34Å; L25-V61 HydrophobicContact CD2-CG1 4.05Å; L25-V61 HydrophobicContact CD2-CG2 3.91Å; C44-V61 HydrophobicContact CB-CB 4.12Å; C44-V61 HydrophobicContact CB-CG2 3.94Å; C44-V61 WeakPolarHBondContact O-CB 3.18Å; C44-V61 WeakPolarHBondContact O-CG2 3.28Å; C44-V61 PolarHBondContact O-N 2.96Å; I46-V61 HydrophobicContact CD1-CG2 3.98Å; I46-V61 HydrophobicContact CG1-CG2 4.08Å; V61-W72 HydrophobicContact CG1-CB 4.28Å; V61-W72 HydrophobicContact CG1-CG 3.93Å; V61-F76 HydrophobicContact CB-CZ 4.43Å; V61-F76 HydrophobicContact CG1-CZ 4.17Å; V61-F76 HydrophobicContact CG2-CE1 4.49Å; V61-F76 HydrophobicContact CG2-CE2 3.94Å; V61-F76 HydrophobicContact CG2-CZ 3.61Å
62E90.3Very high90.8Very high103 Ų10368.5 Ų68.548%0.48135%0.352SS..PPolyproline II helixtrans-50.9142.4176.857167.5167.500113.7K64 W72E62-K64 VanDerWaalsContact CD-CE 3.44Å; E62-K64 WeakPolarHBondContact OE1-CE 3.34Å; E62-K64 IonicContact OE1-NZ 3.16Å; E62-K64 PolarHBondContact OE1-NZ 2.81Å; E62-K64 IonicContact OE2-NZ 3.99Å; E62-K64 PolarHBondContact OE2-NZ 3.06Å; E62-W72 PolarHBondContact O-NE1 3.02Å
63T92.1Very high91Very high31 Ų3166.6 Ų66.619%0.1934%0.342CS..PPolyproline II helixtrans-75.6129.4175.1-50.10000111.2S41 E93S41-T63 WeakPolarHBondContact O-CG2 3.16Å; T63-E93 HydrophobicContact CG2-CB 3.82Å; T63-E93 HydrophobicContact CG2-CG 4.43Å; T63-E93 WeakPolarHBondContact CG2-OE2 3.37Å; T63-E93 PolarHBondContact OG1-OE1 2.7Å
64K90.4Very high91.3Very high51 Ų5165.9 Ų65.922%0.22233%0.331CS..  trans-97.2107.5170.7-63.7-58.9176.3-173.90109.1S41 P42 E62 T67 P70 T71S41-K64 CarbonylContact C-O 3.53Å; S41-K64 VanDerWaalsContact CA-O 3.28Å; S41-K64 WeakPolarHBondContact CA-O 3.46Å; P42-K64 WeakPolarHBondContact CD-O 3.5Å; P42-K64 PolarHBondContact O-N 2.8Å; E62-K64 VanDerWaalsContact CD-CE 3.44Å; E62-K64 WeakPolarHBondContact OE1-CE 3.34Å; E62-K64 IonicContact OE1-NZ 3.16Å; E62-K64 PolarHBondContact OE1-NZ 2.81Å; E62-K64 IonicContact OE2-NZ 3.99Å; E62-K64 PolarHBondContact OE2-NZ 3.06Å; K64-T67 HydrophobicContact CB-CG2 3.74Å; K64-P70 HydrophobicContact CB-CB 3.7Å; K64-P70 HydrophobicContact CG-CB 3.87Å; K64-T71 WeakPolarHBondContact CE-O 3.5Å
65K84.7Confident91.4Very high148 Ų14865.2 Ų65.264%0.64333%0.33SS*.THydrogen-bonded Turntrans-63.9138.6-176.3-64-178.5-179.3172.80111.4T67K65-T67 PolarHBondContact O-N 3.12Å
66K79.4Confident91.4Very high143 Ų14363.3 Ų63.362%0.62232%0.316SS*.THydrogen-bonded Turntrans4754.4166.1-62.5-174.6-180-173.90113.7V39 C40 S41V39-K66 HydrophobicContact CB-CB 3.88Å; V39-K66 HydrophobicContact CB-CG 4.49Å; V39-K66 HydrophobicContact CG1-CB 4.35Å; V39-K66 WeakPolarHBondContact CG1-O 3.46Å; V39-K66 WeakPolarHBondContact O-CA 3.37Å; C40-K66 CarbonylContact O-C 3.55Å; C40-K66 VanDerWaalsContact O-CA 3.26Å; C40-K66 WeakPolarHBondContact O-CA 3.4Å; C40-K66 PolarHBondContact O-N 2.74Å; S41-K66 PolarHBondContact OG-N 3.46Å; S41-K66 VanDerWaalsContact OG-N 3.11Å
67T82.7Confident91.6Very high39 Ų3961.4 Ų61.424%0.23930%0.304CS..  trans-147.4139.4173.6179.90000113.3C40 P42 K64 K65 N69 P70C40-T67 PolarHBondContact O-N 3.48Å; C40-T67 PolarHBondContact SG-O 2.76Å; P42-T67 WeakPolarHBondContact CD-O 3.43Å; P42-T67 HydrophobicContact CG-CG2 4.43Å; P42-T67 VanDerWaalsContact CG-O 3.28Å; P42-T67 WeakPolarHBondContact CG-O 3.16Å; K64-T67 HydrophobicContact CB-CG2 3.74Å; K65-T67 PolarHBondContact O-N 3.12Å; T67-N69 PolarHBondContact OG1-N 3.34Å; T67-N69 VanDerWaalsContact OG1-N 3.12Å; T67-P70 HydrophobicContact CG2-CB 3.83Å
68R85.3Confident91.6Very high95 Ų9559 Ų5936%0.35829%0.291SS..SBendtrans-92.4-7.2171.8-64.5-177.463.7-147.2-4.6113.6K30 L31 V39K30-R68 PolarHBondContact N-O 2.69Å; L31-R68 PolarHBondContact N-O 2.83Å; L31-R68 PolarHBondContact O-NE 2.83Å; L31-R68 PolarHBondContact O-NH2 2.77Å; V39-R68 HydrophobicContact CG1-CG 4.44Å
69N90Very high91.5Very high87 Ų8757.1 Ų57.147%0.46528%0.28SS..SBendtrans-128.459177.5-53.3-69.8000109.4G28 T29 K30 T67G28-N69 CarbonylContact O-C 3.58Å; G28-N69 WeakPolarHBondContact O-CA 3.39Å; T29-N69 WeakPolarHBondContact CA-OD1 3.45Å; K30-N69 PolarHBondContact N-OD1 3.13Å; T67-N69 PolarHBondContact OG1-N 3.34Å; T67-N69 VanDerWaalsContact OG1-N 3.12Å
70P93Very high91.5Very high1 Ų156.2 Ų56.21%0.00628%0.275CS..  trans-60.5139-178.627.5-37.5000111.2R27 G28 L31 P42 K64 T67 W72R27-P70 CarbonylContact C-O 3.45Å; R27-P70 WeakPolarHBondContact CA-O 3.32Å; R27-P70 WeakPolarHBondContact CB-O 3.27Å; G28-P70 PolarHBondContact N-O 3.37Å; L31-P70 HydrophobicContact CD1-CG 3.66Å; P42-P70 HydrophobicContact CB-CG 4.23Å; P42-P70 HydrophobicContact CG-CB 3.77Å; P42-P70 HydrophobicContact CG-CG 3.53Å; K64-P70 HydrophobicContact CB-CB 3.7Å; K64-P70 HydrophobicContact CG-CB 3.87Å; T67-P70 HydrophobicContact CG2-CB 3.83Å; P70-W72 HydrophobicContact CB-CD2 4.33Å; P70-W72 HydrophobicContact CB-CE3 4.28Å; P70-W72 HydrophobicContact CB-CH2 3.7Å; P70-W72 HydrophobicContact CB-CZ2 3.7Å; P70-W72 HydrophobicContact CB-CZ3 3.99Å; P70-W72 HydrophobicContact CG-CE3 4.26Å; P70-W72 HydrophobicContact CG-CH2 3.13Å; P70-W72 HydrophobicContact CG-CZ2 3.62Å; P70-W72 HydrophobicContact CG-CZ3 3.5Å
71T94Very high91.3Very high82 Ų8251.8 Ų51.850%0.50326%0.256SS..EExtended strand (participates in β ladder)trans-112.8115.6169.3-58.80000108.2K64 N73K64-T71 WeakPolarHBondContact CE-O 3.5Å; T71-N73 HydrophobicContact CG2-CB 4.31Å
72W94.7Very high91.1Very high12 Ų1255.2 Ų55.25%0.04527%0.268CS..EExtended strand (participates in β ladder)trans-96.5-42.2175.8-65.6-82.3000111.4L25 L26 P42 C44 V61 E62 P70 S74 L140L25-W72 HydrophobicContact CD1-CE3 3.8Å; L25-W72 HydrophobicContact CD1-CZ3 4.06Å; L25-W72 HydrophobicContact CD2-CB 4.12Å; L25-W72 HydrophobicContact CD2-CD2 3.85Å; L25-W72 HydrophobicContact CD2-CE3 3.9Å; L25-W72 HydrophobicContact CD2-CG 3.96Å; L25-W72 HydrophobicContact CG-CB 4.11Å; L25-W72 HydrophobicContact CG-CD2 4.15Å; L25-W72 HydrophobicContact CG-CE3 3.79Å; L25-W72 HydrophobicContact CG-CG 4.31Å; L26-W72 PolarHBondContact O-N 2.66Å; P42-W72 HydrophobicContact CB-CZ2 4.29Å; C44-W72 WeakPolarHBondContact SG-CH2 3.47Å; V61-W72 HydrophobicContact CG1-CB 4.28Å; V61-W72 HydrophobicContact CG1-CG 3.93Å; E62-W72 PolarHBondContact O-NE1 3.02Å; P70-W72 HydrophobicContact CB-CD2 4.33Å; P70-W72 HydrophobicContact CB-CE3 4.28Å; P70-W72 HydrophobicContact CB-CH2 3.7Å; P70-W72 HydrophobicContact CB-CZ2 3.7Å; P70-W72 HydrophobicContact CB-CZ3 3.99Å; P70-W72 HydrophobicContact CG-CE3 4.26Å; P70-W72 HydrophobicContact CG-CH2 3.13Å; P70-W72 HydrophobicContact CG-CZ2 3.62Å; P70-W72 HydrophobicContact CG-CZ3 3.5Å; W72-S74 PolarHBondContact O-N 2.78Å; W72-S74 PolarHBondContact O-OG 3.27Å; W72-L140 HydrophobicContact CH2-CD2 4.34Å; W72-L140 HydrophobicContact CZ3-CD2 3.94Å
73N92.6Very high91.2Very high88 Ų8853.3 Ų53.347%0.47127%0.27SS..EExtended strand (participates in β ladder)trans48.542.6-176.3-168.641000112.9R24 L25 L26 T71R24-N73 PolarHBondContact NH2-OD1 3.24Å; L25-N73 CarbonylContact O-C 3.49Å; L25-N73 WeakPolarHBondContact O-CA 3.39Å; L25-N73 PolarHBondContact O-N 2.9Å; L25-N73 VanDerWaalsContact O-N 3.12Å; L26-N73 HydrophobicContact CD1-CB 4.28Å; L26-N73 WeakPolarHBondContact CD1-OD1 3.48Å; L26-N73 PolarHBondContact O-N 2.69Å; T71-N73 HydrophobicContact CG2-CB 4.31Å
74S93.1Very high91.2Very high25 Ų2551.9 Ų51.918%0.17526%0.261CS..EExtended strand (participates in β ladder)trans-103.7148.7-176.5-46.40000111R24 L25 W72 F76R24-S74 WeakPolarHBondContact CA-O 3.32Å; L25-S74 PolarHBondContact N-O 3.09Å; L25-S74 PolarHBondContact O-N 2.82Å; W72-S74 PolarHBondContact O-N 2.78Å; W72-S74 PolarHBondContact O-OG 3.27Å; S74-F76 VanDerWaalsContact CB-CE2 3.46Å
75V93.7Very high91.4Very high76 Ų7652.3 Ų52.346%0.46126%0.264SS..EExtended strand (participates in β ladder)trans-126.4127.5178.6179.50000108.6R22 V23 R24R22-V75 HydrophobicContact CG-CG1 3.45Å; R22-V75 VanDerWaalsContact CG-CG1 3.45Å; V23-V75 WeakPolarHBondContact O-CA 3.38Å; R24-V75 HydrophobicContact CB-CG2 4.29Å; R24-V75 HydrophobicContact CG-CG2 3.93Å
76F95.1Very high92Very high30 Ų3045.2 Ų45.213%0.13223%0.233CC..EExtended strand (participates in β ladder)trans-120148.2-179.7-55.4-88.7000109.6R22 V23 L25 I46 V59 V61 S74 F78R22-F76 CarbonylContact C-O 3.55Å; R22-F76 WeakPolarHBondContact CA-O 3.44Å; V23-F76 PolarHBondContact N-O 2.92Å; V23-F76 PolarHBondContact O-N 2.84Å; L25-F76 HydrophobicContact CB-CE2 4.49Å; I46-F76 HydrophobicContact CD1-CD2 3.28Å; I46-F76 HydrophobicContact CD1-CE2 3.42Å; I46-F76 VanDerWaalsContact CD1-CE2 3.42Å; I46-F76 HydrophobicContact CD1-CG 3.88Å; I46-F76 HydrophobicContact CD1-CZ 4.14Å; V59-F76 HydrophobicContact CG1-CD1 3.96Å; V59-F76 HydrophobicContact CG1-CE1 3.72Å; V61-F76 HydrophobicContact CB-CZ 4.43Å; V61-F76 HydrophobicContact CG1-CZ 4.17Å; V61-F76 HydrophobicContact CG2-CE1 4.49Å; V61-F76 HydrophobicContact CG2-CE2 3.94Å; V61-F76 HydrophobicContact CG2-CZ 3.61Å; S74-F76 VanDerWaalsContact CB-CE2 3.46Å; F76-F78 HydrophobicContact CB-CD2 4.18Å; F76-F78 HydrophobicContact CB-CE2 3.62Å; F76-F78 HydrophobicContact CG-CE2 4.47Å
77T94.7Very high92.8Very high3 Ų340.7 Ų40.72%0.01821%0.213CC..EExtended strand (participates in β ladder)trans-119.9125175.4-54.50000108.3V7 H8 L20 L21 M147V7-T77 WeakPolarHBondContact CA-O 3.43Å; V7-T77 HydrophobicContact CG2-CG2 4.24Å; H8-T77 PolarHBondContact N-O 3.26Å; L20-T77 HydrophobicContact CB-CG2 4.25Å; L20-T77 HydrophobicContact CD2-CG2 4.33Å; L21-T77 CarbonylContact O-C 3.55Å; L21-T77 WeakPolarHBondContact O-CA 3.18Å; T77-M147 HydrophobicContact CG2-SD 3.99Å
78F96Very high93.4Very high0 Ų038.9 Ų38.90%020%0.202CC..EExtended strand (participates in β ladder)trans-118135178.7-72.9-98.4000109.8H8 L20 L21 V23 I46 L48 V59 F76 V80 M86H8-F78 HydrophobicContact CB-CD1 3.39Å; H8-F78 HydrophobicContact CB-CD2 4.44Å; H8-F78 HydrophobicContact CB-CE1 3.41Å; H8-F78 VanDerWaalsContact CB-CE1 3.41Å; H8-F78 HydrophobicContact CB-CE2 4.46Å; H8-F78 HydrophobicContact CB-CG 3.94Å; H8-F78 HydrophobicContact CB-CZ 3.98Å; H8-F78 CarbonylContact O-C 3.57Å; H8-F78 VanDerWaalsContact O-CA 3.31Å; H8-F78 WeakPolarHBondContact O-CA 3.27Å; L20-F78 CarbonylContact C-O 3.44Å; L20-F78 WeakPolarHBondContact CA-O 3.27Å; L21-F78 PolarHBondContact N-O 2.83Å; L21-F78 PolarHBondContact O-N 3.21Å; V23-F78 HydrophobicContact CG2-CD2 4.04Å; V23-F78 HydrophobicContact CG2-CE2 4.42Å; I46-F78 HydrophobicContact CB-CZ 4.13Å; I46-F78 HydrophobicContact CG2-CE2 3.68Å; I46-F78 HydrophobicContact CG2-CZ 3.55Å; L48-F78 HydrophobicContact CB-CD1 4.32Å; L48-F78 HydrophobicContact CD2-CD1 4.47Å; V59-F78 HydrophobicContact CB-CZ 4.36Å; V59-F78 HydrophobicContact CG2-CE1 4.08Å; V59-F78 HydrophobicContact CG2-CZ 3.71Å; F76-F78 HydrophobicContact CB-CD2 4.18Å; F76-F78 HydrophobicContact CB-CE2 3.62Å; F76-F78 HydrophobicContact CG-CE2 4.47Å; F78-V80 HydrophobicContact CB-CG1 3.68Å; F78-M86 HydrophobicContact CB-CE 4.2Å; F78-M86 HydrophobicContact CD1-CE 4.06Å; F78-M86 HydrophobicContact CD2-CE 3.91Å; F78-M86 HydrophobicContact CE1-CE 4.42Å; F78-M86 HydrophobicContact CE2-CE 4.28Å; F78-M86 HydrophobicContact CG-CE 3.79Å
79R94.3Very high93.9Very high48 Ų4835 Ų3518%0.18119%0.188CC..EExtended strand (participates in β ladder)trans-83116.9163.7-174.5176.5-65.2109.6-3.6108.3V7 H8 Y10 P12 T18 E19 L20V7-R79 HydrophobicContact CG1-CB 3.98Å; H8-R79 PolarHBondContact O-N 3.3Å; Y10-R79 PolarHBondContact N-O 3.37Å; Y10-R79 WeakPolarHBondContact O-CB 3.17Å; Y10-R79 VanDerWaalsContact O-CD 3.26Å; Y10-R79 WeakPolarHBondContact O-CD 3.37Å; Y10-R79 PolarHBondContact O-NH1 3.4Å; P12-R79 VanDerWaalsContact CA-CZ 3.42Å; P12-R79 VanDerWaalsContact CD-NH1 3.34Å; T18-R79 HydrophobicContact CG2-CG 3.97Å; T18-R79 WeakPolarHBondContact OG1-CD 3.23Å; E19-R79 WeakPolarHBondContact O-CA 3.22Å; L20-R79 HydrophobicContact CD2-CB 4Å; L20-R79 HydrophobicContact CD2-CG 4.42Å
80V94.8Very high94.1Very high0 Ų030.8 Ų30.80%017%0.166CC..EExtended strand (participates in β ladder)trans-131156.2-170.2-56.50000110.9T18 E19 L21 L48 F78 L109 F146T18-V80 CarbonylContact C-O 3.58Å; T18-V80 VanDerWaalsContact CA-O 3.29Å; T18-V80 WeakPolarHBondContact CA-O 3.17Å; E19-V80 PolarHBondContact N-O 2.89Å; E19-V80 PolarHBondContact O-N 2.87Å; L21-V80 HydrophobicContact CB-CG1 4.14Å; L21-V80 HydrophobicContact CB-CG2 3.77Å; L21-V80 HydrophobicContact CD2-CG1 4.33Å; L48-V80 HydrophobicContact CD1-CB 4.29Å; L48-V80 HydrophobicContact CD1-CG1 3.6Å; L48-V80 HydrophobicContact CD2-CG1 3.88Å; L48-V80 HydrophobicContact CG-CG1 4.42Å; F78-V80 HydrophobicContact CB-CG1 3.68Å; V80-L109 HydrophobicContact CB-CD1 3.83Å; V80-L109 HydrophobicContact CG1-CD1 4.07Å; V80-L109 HydrophobicContact CG2-CD1 3.78Å; V80-F146 HydrophobicContact CG2-CE1 3.76Å; V80-F146 HydrophobicContact CG2-CZ 4.47Å
81T92.4Very high94Very high20 Ų2032.7 Ų32.712%0.12317%0.173CC..  trans-96.7156.1160.569.70000108.9Y10 N16 T18 A83 C84Y10-T81 HydrophobicContact CD2-CG2 4.21Å; Y10-T81 HydrophobicContact CE2-CG2 3.85Å; N16-T81 HydrophobicContact CB-CG2 3.81Å; T18-T81 HydrophobicContact CG2-CG2 3.88Å; T81-A83 PolarHBondContact O-N 3.4Å; T81-C84 WeakPolarHBondContact O-CB 3.18Å; T81-C84 PolarHBondContact O-N 3.26Å; T81-C84 VanDerWaalsContact O-N 3.07Å; T81-C84 PolarHBondContact OG1-SG 3.09Å
82R90.7Very high93.7Very high77 Ų7730 Ų3029%0.29116%0.156SC..THydrogen-bonded Turntrans-61.8-23.7177.2-68.3-68.3-178.4148-2.6113.3E19 C84 N110 F146E19-R82 IonicContact OE1-CZ 2.73Å; E19-R82 IonicContact OE1-NE 3.2Å; E19-R82 PolarHBondContact OE1-NE 3.05Å; E19-R82 IonicContact OE1-NH2 3.82Å; E19-R82 PolarHBondContact OE1-NH2 2.95Å; E19-R82 IonicContact OE2-CZ 2.99Å; E19-R82 IonicContact OE2-NE 2.92Å; E19-R82 IonicContact OE2-NH2 2.67Å; E19-R82 PolarHBondContact OE2-NH2 3.03Å; R82-C84 PolarHBondContact O-N 2.88Å; R82-N110 WeakPolarHBondContact O-CB 3.39Å; R82-N110 PolarHBondContact O-N 3.44Å; R82-F146 VanDerWaalsContact CZ-CZ 3.45Å
83A90.6Very high93.1Very high63 Ų6332.4 Ų32.452%0.52117%0.168SC..THydrogen-bonded Turntrans-74.3-9.7176.700000114.2T81T81-A83 PolarHBondContact O-N 3.4Å
84C94Very high92.2Very high1 Ų130.6 Ų30.61%0.00716%0.158CC..  trans-75.6161.7-178.7-65.30000113.3L48 E49 T81 R82 L109L48-C84 HydrophobicContact CD1-CB 3.63Å; L48-C84 HydrophobicContact CG-CB 4.47Å; E49-C84 CarbonylContact O-C 3.47Å; E49-C84 VanDerWaalsContact O-CA 3.22Å; E49-C84 WeakPolarHBondContact O-CA 3.46Å; E49-C84 VanDerWaalsContact O-CB 3.28Å; E49-C84 WeakPolarHBondContact O-CB 3.5Å; T81-C84 WeakPolarHBondContact O-CB 3.18Å; T81-C84 PolarHBondContact O-N 3.26Å; T81-C84 VanDerWaalsContact O-N 3.07Å; T81-C84 PolarHBondContact OG1-SG 3.09Å; R82-C84 PolarHBondContact O-N 2.88Å; C84-L109 HydrophobicContact CB-CD1 3.99Å; C84-L109 WeakPolarHBondContact O-CG 3.36Å; C84-L109 PolarHBondContact O-N 2.99Å
85Q94.3Very high90.5Very high60 Ų6038.3 Ų38.328%0.2818%0.184SC..EExtended strand (participates in β ladder)trans-118.2135.1170-170.7173.54800110E49 S106E49-Q85 PolarHBondContact N-O 3.49Å; E49-Q85 PolarHBondContact O-N 3.36Å; Q85-S106 WeakPolarHBondContact CG-OG 3.38Å; Q85-S106 PolarHBondContact NE2-OG 2.96Å
86M95.8Very high88.2Confident0 Ų039.4 Ų39.40%019%0.186CC..EExtended strand (participates in β ladder)trans-101.2122.3174.7-175.258.271.200109.7L21 V23 I46 L48 F78 I88 S106 R107 L109 F144L21-M86 HydrophobicContact CD2-CE 4.17Å; V23-M86 HydrophobicContact CG2-CE 4.22Å; I46-M86 HydrophobicContact CG2-CE 4.48Å; I46-M86 HydrophobicContact CG2-SD 3.45Å; I46-M86 WeakPolarHBondContact CG2-SD 3.3Å; L48-M86 HydrophobicContact CB-CE 4.27Å; L48-M86 HydrophobicContact CD1-CE 3.87Å; F78-M86 HydrophobicContact CB-CE 4.2Å; F78-M86 HydrophobicContact CD1-CE 4.06Å; F78-M86 HydrophobicContact CD2-CE 3.91Å; F78-M86 HydrophobicContact CE1-CE 4.42Å; F78-M86 HydrophobicContact CE2-CE 4.28Å; F78-M86 HydrophobicContact CG-CE 3.79Å; M86-I88 HydrophobicContact CG-CD1 3.97Å; M86-S106 CarbonylContact O-C 3.5Å; M86-S106 WeakPolarHBondContact O-CA 3.29Å; M86-R107 PolarHBondContact N-O 3.26Å; M86-R107 PolarHBondContact O-N 2.88Å; M86-L109 HydrophobicContact CB-CD2 4.26Å; M86-F144 HydrophobicContact CB-CE1 4.47Å; M86-F144 HydrophobicContact CG-CE1 3.88Å
87K96Very high86.4Confident47 Ų4744.1 Ų44.120%0.20420%0.203CC..EExtended strand (participates in β ladder)trans-114.6132.1175.4-72.3-174.2-173157.50110.7R47 E49 L89 V105R47-K87 HydrophobicContact CB-CB 4.46Å; R47-K87 PolarHBondContact N-O 2.99Å; R47-K87 PolarHBondContact O-N 3.27Å; E49-K87 WeakPolarHBondContact OE1-CD 3.38Å; E49-K87 IonicContact OE1-NZ 2.64Å; E49-K87 PolarHBondContact OE1-NZ 2.98Å; E49-K87 WeakPolarHBondContact OE2-CE 3.37Å; E49-K87 IonicContact OE2-NZ 3.62Å; E49-K87 PolarHBondContact OE2-NZ 3.18Å; K87-L89 HydrophobicContact CB-CD1 4.17Å; K87-V105 CarbonylContact C-O 3.56Å; K87-V105 WeakPolarHBondContact CA-O 3.24Å
88I97.2Very high85.2Confident1 Ų153.3 Ų53.31%0.00524%0.243CC..EExtended strand (participates in β ladder)trans-114.9103.4173.1-5783.6000106.5C44 M45 I46 M86 F104 V105 L140 L142 F144C44-I88 HydrophobicContact CB-CG2 4.15Å; M45-I88 WeakPolarHBondContact O-CA 3.25Å; I46-I88 HydrophobicContact CG1-CG1 4.39Å; I46-I88 HydrophobicContact CG1-CG2 4.46Å; I46-I88 HydrophobicContact CG2-CG1 4.47Å; M86-I88 HydrophobicContact CG-CD1 3.97Å; I88-F104 CarbonylContact O-C 3.49Å; I88-F104 WeakPolarHBondContact O-CA 3.42Å; I88-V105 PolarHBondContact N-O 2.69Å; I88-V105 PolarHBondContact O-N 3.41Å; I88-L140 HydrophobicContact CB-CD1 4.21Å; I88-L140 HydrophobicContact CG2-CD1 3.59Å; I88-L142 HydrophobicContact CD1-CD1 4.02Å; I88-L142 HydrophobicContact CG1-CD1 4.27Å; I88-F144 HydrophobicContact CD1-CE1 4.07Å; I88-F144 HydrophobicContact CD1-CZ 3.72Å
89L95.6Very high84.4Confident13 Ų1355.5 Ų55.57%0.06826%0.255CS..EExtended strand (participates in β ladder)trans-91.3136.4179.4-56.297.5000109.2C44 M45 R47 K87 Y91 L101 F104C44-L89 CarbonylContact C-O 3.6Å; C44-L89 VanDerWaalsContact CA-O 3.22Å; C44-L89 WeakPolarHBondContact CA-O 3.37Å; M45-L89 HydrophobicContact CB-CB 4.27Å; M45-L89 HydrophobicContact CB-CD1 4.34Å; M45-L89 PolarHBondContact N-O 2.98Å; M45-L89 PolarHBondContact O-N 3.24Å; R47-L89 HydrophobicContact CB-CD1 3.95Å; K87-L89 HydrophobicContact CB-CD1 4.17Å; L89-Y91 HydrophobicContact CB-CD2 4.22Å; L89-Y91 HydrophobicContact CB-CE2 3.59Å; L89-Y91 HydrophobicContact CD2-CE2 4.36Å; L89-L101 HydrophobicContact CB-CD1 3.82Å; L89-L101 HydrophobicContact CD2-CD1 3.95Å; L89-L101 HydrophobicContact CG-CD1 4.42Å; L89-F104 HydrophobicContact CG-CB 4.23Å
90V93.8Very high83.6Confident0 Ų055.7 Ų55.70%026%0.261CS..EExtended strand (participates in β ladder)trans-109.7121177.2-174.20000108.3L31 P42 M102 G103 L126 L140L31-V90 HydrophobicContact CD1-CG1 4.03Å; L31-V90 HydrophobicContact CD2-CG1 4.33Å; P42-V90 HydrophobicContact CB-CG1 4.3Å; V90-M102 HydrophobicContact CB-CB 4.43Å; V90-M102 HydrophobicContact CG1-CB 4.35Å; V90-M102 HydrophobicContact CG1-SD 3.99Å; V90-M102 WeakPolarHBondContact O-CB 3.45Å; V90-M102 PolarHBondContact O-N 3.42Å; V90-G103 PolarHBondContact N-O 2.91Å; V90-G103 PolarHBondContact O-N 2.79Å; V90-L126 HydrophobicContact CG2-CD1 4.23Å; V90-L126 HydrophobicContact CG2-CD2 3.75Å; V90-L140 HydrophobicContact CG2-CD1 3.72Å; V90-L140 HydrophobicContact CG2-CD2 3.97Å; V90-L140 HydrophobicContact CG2-CG 4.11Å
91Y91.5Very high83.2Confident40 Ų4058.3 Ų58.316%0.15728%0.275CS..EExtended strand (participates in β ladder)trans-112.6151178.6-70.7-87.8000110.7P42 Y43 M45 L89 D99 V100 L101P42-Y91 WeakPolarHBondContact CA-O 3.24Å; Y43-Y91 VanDerWaalsContact CE1-CB 3.42Å; Y43-Y91 HydrophobicContact CE1-CG 4.3Å; Y43-Y91 AromaticContact CE2-CD2 3.78Å; Y43-Y91 HydrophobicContact CE2-CD2 3.78Å; Y43-Y91 HydrophobicContact CE2-CG 4.08Å; Y43-Y91 AromaticContact CZ-CD2 3.96Å; Y43-Y91 AromaticContact CZ-CG 3.78Å; Y43-Y91 PolarHBondContact N-O 2.68Å; Y43-Y91 PolarHBondContact O-N 3.11Å; M45-Y91 HydrophobicContact CB-CD2 4.32Å; M45-Y91 HydrophobicContact CB-CE2 3.98Å; L89-Y91 HydrophobicContact CB-CD2 4.22Å; L89-Y91 HydrophobicContact CB-CE2 3.59Å; L89-Y91 HydrophobicContact CD2-CE2 4.36Å; Y91-D99 HydrophobicContact CD1-CB 4.14Å; Y91-V100 CarbonylContact C-O 3.24Å; Y91-V100 WeakPolarHBondContact CA-O 3.45Å; Y91-L101 HydrophobicContact CD1-CB 4.11Å; Y91-L101 HydrophobicContact CD1-CD1 4.3Å; Y91-L101 HydrophobicContact CD2-CD1 4.48Å; Y91-L101 HydrophobicContact CE1-CB 3.78Å; Y91-L101 HydrophobicContact CE1-CD1 3.91Å; Y91-L101 HydrophobicContact CE1-CG 4.43Å; Y91-L101 HydrophobicContact CE2-CD1 4.13Å
92D86.2Confident82.9Confident26 Ų2658.3 Ų58.314%0.13927%0.273CS..EExtended strand (participates in β ladder)trans-94.4117.6162-160.8-0.5000108.8C40 S41 N94 V100 M102C40-D92 WeakPolarHBondContact CA-OD1 3.32Å; C40-D92 WeakPolarHBondContact CB-OD1 3.32Å; C40-D92 VanDerWaalsContact CB-OD2 3.24Å; C40-D92 WeakPolarHBondContact CB-OD2 3.41Å; S41-D92 PolarHBondContact N-OD1 3.49Å; D92-N94 PolarHBondContact O-N 2.98Å; D92-V100 PolarHBondContact N-O 2.69Å; D92-V100 PolarHBondContact O-N 3.43Å; D92-M102 HydrophobicContact CB-CG 4.14Å; D92-M102 HydrophobicContact CB-SD 4.11Å
93E82.5Confident82.9Confident62 Ų6254.7 Ų54.729%0.2926%0.26SS..  trans-66.7122.9178.8-176.5-176.3-127.100110.2S41 Y43 T63 D99S41-E93 WeakPolarHBondContact O-CB 3.26Å; S41-E93 PolarHBondContact O-N 2.76Å; S41-E93 VanDerWaalsContact O-N 3.09Å; Y43-E93 HydrophobicContact CD1-CB 3.99Å; Y43-E93 HydrophobicContact CE1-CB 4.15Å; T63-E93 HydrophobicContact CG2-CB 3.82Å; T63-E93 HydrophobicContact CG2-CG 4.43Å; T63-E93 WeakPolarHBondContact CG2-OE2 3.37Å; T63-E93 PolarHBondContact OG1-OE1 2.7Å; E93-D99 WeakPolarHBondContact CA-OD1 3.09Å
94N72.9Confident83Confident51 Ų5153.6 Ų53.627%0.27324%0.244SC..  trans-120.5130.5174.5-161.5-45.6000110.4D92 L96 R97 D99D92-N94 PolarHBondContact O-N 2.98Å; N94-L96 PolarHBondContact OD1-N 3.05Å; N94-L96 VanDerWaalsContact OD1-N 3.12Å; N94-R97 PolarHBondContact OD1-N 3.12Å; N94-D99 PolarHBondContact N-OD1 3.23Å
95R58.2Low83Confident187 Ų18753.8 Ų53.871%0.70625%0.245SC*.SBendtrans-77.9-18.7-176.3-69.1-176.4175.4-173.8-4.3114.1
96L45.8Very low83Confident99 Ų9952.2 Ų52.252%0.51824%0.24SC..SBendtrans-122.5-22.8-169.3-60.9159.5000113.2N94 Y451N94-L96 PolarHBondContact OD1-N 3.05Å; N94-L96 VanDerWaalsContact OD1-N 3.12Å; L96-Y451 HydrophobicContact CD1-CD1 3.67Å; L96-Y451 HydrophobicContact CD1-CD2 3.36Å; L96-Y451 HydrophobicContact CD1-CE1 3.53Å; L96-Y451 HydrophobicContact CD1-CE2 3.22Å; L96-Y451 HydrophobicContact CD1-CG 3.6Å; L96-Y451 HydrophobicContact CD2-CE1 4.32Å; L96-Y451 HydrophobicContact CD2-CE2 3.97Å; L96-Y451 VanDerWaalsContact CD2-OH 3.27Å; L96-Y451 WeakPolarHBondContact CD2-OH 3.33Å; L96-Y451 HydrophobicContact CG-CE1 4.34Å; L96-Y451 HydrophobicContact CG-CE2 4.2Å
97R56.3Low82.8Confident129 Ų12954.1 Ų54.149%0.48725%0.247SC..SBendtrans-120.9168.9179.9-50.2-168.4-149.1-158.99.3109.1N94 D99 D398N94-R97 PolarHBondContact OD1-N 3.12Å; R97-D99 PolarHBondContact O-N 2.99Å; R97-D398 PolarHBondContact NH1-O 2.61Å
98K69.2Low82.7Confident195 Ų19555.3 Ų55.385%0.84826%0.259SS*.PPolyproline II helixtrans-60135.3171.1-171.3174.4-178.4175.50110V100K98-V100 PolarHBondContact O-N 3.03Å
99D80.2Confident82.4Confident47 Ų4755.3 Ų55.325%0.25126%0.259SS..PPolyproline II helixtrans-55.4136.5176.3-67-18.7000111.5Y43 Y91 E93 N94 R97Y43-D99 HydrophobicContact CE1-CB 4.27Å; Y43-D99 VanDerWaalsContact CE1-OD2 3.23Å; Y43-D99 WeakPolarHBondContact CE1-OD2 3.26Å; Y43-D99 VanDerWaalsContact CZ-OD2 3.28Å; Y43-D99 PolarHBondContact OH-OD2 3.31Å; Y91-D99 HydrophobicContact CD1-CB 4.14Å; E93-D99 WeakPolarHBondContact CA-OD1 3.09Å; N94-D99 PolarHBondContact N-OD1 3.23Å; R97-D99 PolarHBondContact O-N 2.99Å
100V77.8Confident82Confident51 Ų5160.1 Ų60.131%0.30929%0.285SS..EExtended strand (participates in β ladder)trans-95.1121.4-172.6179.70000109.7Y91 D92 K98 M102Y91-V100 CarbonylContact C-O 3.24Å; Y91-V100 WeakPolarHBondContact CA-O 3.45Å; D92-V100 PolarHBondContact N-O 2.69Å; D92-V100 PolarHBondContact O-N 3.43Å; K98-V100 PolarHBondContact O-N 3.03Å; V100-M102 PolarHBondContact O-N 3.1Å; V100-M102 VanDerWaalsContact O-N 3.15Å
101L86.9Confident81.5Confident56 Ų5663 Ų6329%0.29330%0.3SS..EExtended strand (participates in β ladder)trans-67.7111.3173.2-178.867.4000110.1L89 Y91L89-L101 HydrophobicContact CB-CD1 3.82Å; L89-L101 HydrophobicContact CD2-CD1 3.95Å; L89-L101 HydrophobicContact CG-CD1 4.42Å; Y91-L101 HydrophobicContact CD1-CB 4.11Å; Y91-L101 HydrophobicContact CD1-CD1 4.3Å; Y91-L101 HydrophobicContact CD2-CD1 4.48Å; Y91-L101 HydrophobicContact CE1-CB 3.78Å; Y91-L101 HydrophobicContact CE1-CD1 3.91Å; Y91-L101 HydrophobicContact CE1-CG 4.43Å; Y91-L101 HydrophobicContact CE2-CD1 4.13Å
102M85Confident80.9Confident19 Ų1964.3 Ų64.39%0.09433%0.326CS..EExtended strand (participates in β ladder)trans-77.3-37.9178.2-56.8-176.976.500111.6L31 G32 C40 P42 V90 D92 V100L31-M102 HydrophobicContact CB-CE 3.76Å; G32-M102 VanDerWaalsContact O-CE 3.25Å; G32-M102 WeakPolarHBondContact O-CE 3.3Å; C40-M102 HydrophobicContact CB-CE 4.16Å; C40-M102 HydrophobicContact CB-SD 4.48Å; P42-M102 HydrophobicContact CB-SD 4.47Å; V90-M102 HydrophobicContact CB-CB 4.43Å; V90-M102 HydrophobicContact CG1-CB 4.35Å; V90-M102 HydrophobicContact CG1-SD 3.99Å; V90-M102 WeakPolarHBondContact O-CB 3.45Å; V90-M102 PolarHBondContact O-N 3.42Å; D92-M102 HydrophobicContact CB-CG 4.14Å; D92-M102 HydrophobicContact CB-SD 4.11Å; V100-M102 PolarHBondContact O-N 3.1Å; V100-M102 VanDerWaalsContact O-N 3.15Å
103G90.3Very high80.7Confident1 Ų168.9 Ų68.91%0.0135%0.35CS..EExtended strand (participates in β ladder)trans169.2179.2-179.500000111.6V90 Q127V90-G103 PolarHBondContact N-O 2.91Å; V90-G103 PolarHBondContact O-N 2.79Å; G103-Q127 VanDerWaalsContact CA-O 3.26Å; G103-Q127 WeakPolarHBondContact CA-O 3.44Å
104F93.8Very high80.9Confident41 Ų4166.6 Ų66.618%0.1834%0.339CS..EExtended strand (participates in β ladder)trans-145155.1178.364.3-86.1000112.4I88 L89 Q127I88-F104 CarbonylContact O-C 3.49Å; I88-F104 WeakPolarHBondContact O-CA 3.42Å; L89-F104 HydrophobicContact CG-CB 4.23Å; F104-Q127 WeakPolarHBondContact CD1-O 3.5Å; F104-Q127 HydrophobicContact CD2-CB 4.35Å; F104-Q127 HydrophobicContact CE1-CB 4.12Å; F104-Q127 HydrophobicContact CE2-CB 3.93Å; F104-Q127 HydrophobicContact CZ-CB 3.8Å; F104-Q127 PolarHBondContact N-O 2.79Å; F104-Q127 PolarHBondContact O-N 2.68Å
105V94.4Very high81.4Confident4 Ų467.9 Ų67.92%0.02435%0.349CS..EExtended strand (participates in β ladder)trans-106.4136.3163.4177.70000107.6K87 I88 Y124 L126 L140 L142K87-V105 CarbonylContact C-O 3.56Å; K87-V105 WeakPolarHBondContact CA-O 3.24Å; I88-V105 PolarHBondContact N-O 2.69Å; I88-V105 PolarHBondContact O-N 3.41Å; V105-Y124 HydrophobicContact CG1-CD1 3.67Å; V105-Y124 HydrophobicContact CG1-CG 3.95Å; V105-L126 HydrophobicContact CG2-CD2 3.89Å; V105-L140 HydrophobicContact CG2-CB 4.31Å; V105-L140 HydrophobicContact CG2-CD1 4.03Å; V105-L140 HydrophobicContact CG2-CG 4.37Å; V105-L142 HydrophobicContact CB-CD1 4.12Å; V105-L142 HydrophobicContact CG1-CD1 3.98Å; V105-L142 HydrophobicContact CG2-CD1 4.21Å
106S93.8Very high82.6Confident27 Ų2763.1 Ų63.119%0.18934%0.341CS..EExtended strand (participates in β ladder)trans-125.4131.3175.3-170.40000110.5Q85 M86Q85-S106 WeakPolarHBondContact CG-OG 3.38Å; Q85-S106 PolarHBondContact NE2-OG 2.96Å; M86-S106 CarbonylContact O-C 3.5Å; M86-S106 WeakPolarHBondContact O-CA 3.29Å
107R92.2Very high84.2Confident40 Ų4066 Ų6615%0.15135%0.352CS..EExtended strand (participates in β ladder)trans-128.9120.6-178.4-171.469.4-171.8-1453.3111M86 D111 I114 Y124 F144M86-R107 PolarHBondContact N-O 3.26Å; M86-R107 PolarHBondContact O-N 2.88Å; R107-D111 IonicContact CZ-OD2 2.68Å; R107-D111 IonicContact NE-OD2 3.47Å; R107-D111 PolarHBondContact NE-OD2 2.96Å; R107-D111 IonicContact NH2-OD1 2.83Å; R107-D111 IonicContact NH2-OD2 3.66Å; R107-D111 PolarHBondContact NH2-OD2 2.94Å; R107-I114 HydrophobicContact CG-CD1 4.25Å; R107-Y124 PolarHBondContact NH1-OH 2.65Å; R107-Y124 VanDerWaalsContact NH1-OH 3.15Å; R107-F144 HydrophobicContact CB-CE2 4.5Å; R107-F144 HydrophobicContact CB-CZ 4.33Å; R107-F144 HydrophobicContact CG-CD2 4.47Å; R107-F144 HydrophobicContact CG-CE2 4.45Å
108T92.6Very high85.3Confident73 Ų7363.2 Ų63.245%0.44836%0.356SS..EExtended strand (participates in β ladder)trans-79.6134.4171.2-55.70000109.8
109L91.7Very high86Confident0 Ų056 Ų560%033%0.329CS..THydrogen-bonded Turntrans-89.4-11.3-172.7-56.4-176.1000114.6L21 V80 C84 M86 I114 F146L21-L109 HydrophobicContact CD2-CD1 3.97Å; L21-L109 HydrophobicContact CD2-CD2 3.68Å; V80-L109 HydrophobicContact CB-CD1 3.83Å; V80-L109 HydrophobicContact CG1-CD1 4.07Å; V80-L109 HydrophobicContact CG2-CD1 3.78Å; C84-L109 HydrophobicContact CB-CD1 3.99Å; C84-L109 WeakPolarHBondContact O-CG 3.36Å; C84-L109 PolarHBondContact O-N 2.99Å; M86-L109 HydrophobicContact CB-CD2 4.26Å; L109-I114 HydrophobicContact CD2-CD1 3.57Å; L109-F146 HydrophobicContact CB-CZ 4.45Å
110N86.9Confident86.3Confident115 Ų11560.5 Ų60.562%0.61535%0.353SS*.THydrogen-bonded Turntrans-93.613.6179-156.621.1000114.4R82 G112R82-N110 WeakPolarHBondContact O-CB 3.39Å; R82-N110 PolarHBondContact O-N 3.44Å; N110-G112 VanDerWaalsContact C-N 3.26Å; N110-G112 PolarHBondContact O-N 3.27Å
111D83.5Confident87Confident61 Ų6159.3 Ų59.333%0.32635%0.347SS..SBendtrans-78.8-7-174.1657.8000114.1R107 L113R107-D111 IonicContact CZ-OD2 2.68Å; R107-D111 IonicContact NE-OD2 3.47Å; R107-D111 PolarHBondContact NE-OD2 2.96Å; R107-D111 IonicContact NH2-OD1 2.83Å; R107-D111 IonicContact NH2-OD2 3.66Å; R107-D111 PolarHBondContact NH2-OD2 2.94Å; D111-L113 HydrophobicContact CB-CD1 4.31Å; D111-L113 HydrophobicContact CB-CG 4.31Å; D111-L113 PolarHBondContact O-N 3.23Å; D111-L113 WeakPolarHBondContact OD1-CB 3.3Å; D111-L113 PolarHBondContact OD1-N 2.98Å
112G78.6Confident87.2Confident67 Ų6762.1 Ų62.169%0.69136%0.358SS*.SBendtrans69.13.8-175.900000114.5N110N110-G112 VanDerWaalsContact C-N 3.26Å; N110-G112 PolarHBondContact O-N 3.27Å
113L82.8Confident87.7Confident122 Ų12266.9 Ų66.964%0.63938%0.38SS*.  trans-91.7-16.7-177.6-64.1174.7000112.6D111D111-L113 HydrophobicContact CB-CD1 4.31Å; D111-L113 HydrophobicContact CB-CG 4.31Å; D111-L113 PolarHBondContact O-N 3.23Å; D111-L113 WeakPolarHBondContact OD1-CB 3.3Å; D111-L113 PolarHBondContact OD1-N 2.98Å
114I85.6Confident87.9Confident14 Ų1468.5 Ų68.57%0.07239%0.386CS..  trans-86.1113.5178.3-56.1176.9000109.6L21 R107 L109 F144 F146L21-I114 HydrophobicContact CD1-CG2 4.02Å; R107-I114 HydrophobicContact CG-CD1 4.25Å; L109-I114 HydrophobicContact CD2-CD1 3.57Å; I114-F144 HydrophobicContact CD1-CB 4.15Å; I114-F144 HydrophobicContact CG1-CB 4.34Å; I114-F144 HydrophobicContact CG2-CB 4.06Å; I114-F146 HydrophobicContact CB-CD2 4.06Å; I114-F146 HydrophobicContact CB-CE2 3.78Å; I114-F146 HydrophobicContact CD1-CE2 4.38Å; I114-F146 HydrophobicContact CG2-CD2 3.52Å; I114-F146 HydrophobicContact CG2-CE2 3.57Å
115T83.9Confident87.8Confident77 Ų7769.9 Ų69.947%0.47241%0.406SS..  trans-86.3172.5-177.756.90000113.1Q117 H145 F146T115-Q117 PolarHBondContact OG1-O 3.37Å; T115-H145 CarbonylContact O-C 3.14Å; T115-H145 VanDerWaalsContact O-CA 3.23Å; T115-H145 WeakPolarHBondContact O-CA 3.49Å; T115-H145 VanDerWaalsContact O-CB 3.28Å; T115-H145 WeakPolarHBondContact O-CB 3.3Å; T115-F146 PolarHBondContact O-N 2.87Å
116T82.4Confident87.6Confident88 Ų8870.4 Ų70.454%0.5441%0.408SS..SBendtrans-88.4-18.8170.252.50000113.7F146T116-F146 VanDerWaalsContact CA-O 3.24Å; T116-F146 WeakPolarHBondContact CA-O 3.39Å; T116-F146 HydrophobicContact CG2-CB 4.31Å
117Q80.2Confident87.3Confident159 Ų15974.1 Ų74.174%0.74342%0.422SS*.SBendtrans-79.7136.7170.6-63.6-176.67.300109.3T115 P119T115-Q117 PolarHBondContact OG1-O 3.37Å; Q117-P119 WeakPolarHBondContact O-CD 3.17Å
118A80.2Confident86.6Confident70 Ų7074.2 Ų74.258%0.57943%0.429SS*.  trans-71.7109.2178.900000110.5
119P84.2Confident85.3Confident45 Ų4573.7 Ų73.729%0.29244%0.438SS..PPolyproline II helixtrans-79.6163.8179.432.8-29.9000110.7Q117Q117-P119 WeakPolarHBondContact O-CD 3.17Å
120N86.4Confident83.4Confident141 Ų14176.8 Ų76.875%0.75446%0.457SS*.PPolyproline II helixtrans-64.3145.7166.4-72.9-38000109.8E122N120-E122 PolarHBondContact O-N 2.89Å
121P91.2Very high81.1Confident26 Ų2676.2 Ų76.217%0.16947%0.469CS..PPolyproline II helixtrans-56.9125.3174.7-27.537.1000112.4L26 F141 L142L26-P121 HydrophobicContact CB-CB 4.15Å; L26-P121 HydrophobicContact CB-CG 4.16Å; L26-P121 HydrophobicContact CD2-CB 4.11Å; L26-P121 HydrophobicContact CD2-CG 4.1Å; P121-F141 HydrophobicContact CB-CB 4.28Å; P121-L142 CarbonylContact C-O 3.57Å; P121-L142 WeakPolarHBondContact CA-O 3.18Å
122E92.7Very high79.2Confident114 Ų11477.3 Ų77.353%0.53348%0.481SS..EExtended strand (participates in β ladder)trans-99.5158.9178.7-64-179.5165.400110.7N120 Y124 F141 L142N120-E122 PolarHBondContact O-N 2.89Å; E122-Y124 HydrophobicContact CB-CE2 4Å; E122-Y124 VanDerWaalsContact O-CD2 3.3Å; E122-Y124 WeakPolarHBondContact O-CD2 3.36Å; E122-F141 CarbonylContact O-C 3.55Å; E122-F141 VanDerWaalsContact O-CA 3.27Å; E122-F141 WeakPolarHBondContact O-CA 3.24Å; E122-L142 PolarHBondContact N-O 3.16Å; E122-L142 PolarHBondContact O-N 3.42Å
123E94.5Very high77.3Confident119 Ų11984.2 Ų84.256%0.55649%0.492SS*.EExtended strand (participates in β ladder)trans-83.4122.2179-171.6177.6175.800111.5S139 F141E123-S139 VanDerWaalsContact CG-CB 3.48Å; E123-S139 WeakPolarHBondContact OE1-CB 3.5Å; E123-S139 PolarHBondContact OE1-OG 3.29Å; E123-F141 HydrophobicContact CB-CD1 4.49Å; E123-F141 HydrophobicContact CB-CE1 3.99Å; E123-F141 HydrophobicContact CB-CE2 4.38Å; E123-F141 HydrophobicContact CB-CZ 3.91Å; E123-F141 HydrophobicContact CG-CE2 4.06Å; E123-F141 HydrophobicContact CG-CZ 3.95Å
124Y93.8Very high75.6Confident35 Ų3582.4 Ų82.414%0.13750%0.503CS..EExtended strand (participates in β ladder)trans-113115.4174.7-70.4-99.8000109.6V105 R107 E122 S139 L140 L142 F144V105-Y124 HydrophobicContact CG1-CD1 3.67Å; V105-Y124 HydrophobicContact CG1-CG 3.95Å; R107-Y124 PolarHBondContact NH1-OH 2.65Å; R107-Y124 VanDerWaalsContact NH1-OH 3.15Å; E122-Y124 HydrophobicContact CB-CE2 4Å; E122-Y124 VanDerWaalsContact O-CD2 3.3Å; E122-Y124 WeakPolarHBondContact O-CD2 3.36Å; Y124-S139 CarbonylContact O-C 3.46Å; Y124-S139 WeakPolarHBondContact O-CA 3.4Å; Y124-S139 WeakPolarHBondContact O-CB 3.46Å; Y124-L140 PolarHBondContact N-O 3.03Å; Y124-L140 PolarHBondContact O-N 2.77Å; Y124-L142 HydrophobicContact CD2-CB 3.79Å; Y124-L142 HydrophobicContact CD2-CD1 4.21Å; Y124-L142 HydrophobicContact CD2-CG 4.22Å; Y124-L142 HydrophobicContact CE2-CB 3.94Å; Y124-L142 HydrophobicContact CG-CD1 4.3Å; Y124-F144 HydrophobicContact CE1-CE2 4.4Å; Y124-F144 HydrophobicContact CE2-CE2 4.29Å
125A91.8Very high74.3Confident71 Ų7189.9 Ų89.959%0.58754%0.535SS*.EExtended strand (participates in β ladder)trans-67.4137.4174.400000111
126L91.2Very high73.5Confident15 Ų1591 Ų918%0.07955%0.546CS..PPolyproline II helixtrans-72.7136.3177.6-71.5171.1000111.4L31 V90 V105 I137 G138 L140L31-L126 HydrophobicContact CD2-CD1 3.48Å; L31-L126 VanDerWaalsContact CD2-CD1 3.48Å; V90-L126 HydrophobicContact CG2-CD1 4.23Å; V90-L126 HydrophobicContact CG2-CD2 3.75Å; V105-L126 HydrophobicContact CG2-CD2 3.89Å; L126-I137 HydrophobicContact CB-CD1 3.71Å; L126-I137 HydrophobicContact CB-CG1 3.81Å; L126-I137 WeakPolarHBondContact O-CG1 3.29Å; L126-G138 WeakPolarHBondContact CB-O 3.39Å; L126-G138 PolarHBondContact N-O 2.89Å; L126-L140 HydrophobicContact CD2-CD1 4.17Å; L126-L140 HydrophobicContact CD2-CG 4.08Å
127Q87.9Confident73.4Confident104 Ų10488.2 Ų88.249%0.48653%0.527SS..BIsolated β-bridgetrans-91.5140.6171.8-59.4179.111.200109.7G103 F104G103-Q127 VanDerWaalsContact CA-O 3.26Å; G103-Q127 WeakPolarHBondContact CA-O 3.44Å; F104-Q127 WeakPolarHBondContact CD1-O 3.5Å; F104-Q127 HydrophobicContact CD2-CB 4.35Å; F104-Q127 HydrophobicContact CE1-CB 4.12Å; F104-Q127 HydrophobicContact CE2-CB 3.93Å; F104-Q127 HydrophobicContact CZ-CB 3.8Å; F104-Q127 PolarHBondContact N-O 2.79Å; F104-Q127 PolarHBondContact O-N 2.68Å
128S76.8Confident73.9Confident43 Ų4380.7 Ų80.730%0.30149%0.492SS..PPolyproline II helixtrans-89.7135.4176.8-167.30000110.4T130S128-T130 PolarHBondContact O-N 2.99Å; S128-T130 PolarHBondContact OG-N 2.73Å; S128-T130 PolarHBondContact OG-O 2.81Å; S128-T130 PolarHBondContact OG-OG1 2.9Å
129G64.2Low74.5Confident61 Ų6177.8 Ų77.863%0.62947%0.468SS*.SBendtrans-72.6-15.5171.100000113.8
130T51.9Low75.1Confident65 Ų6575.7 Ų75.740%0.39945%0.454SS..SBendtrans-111142.6-179.5560000110.3R34 S128 S132R34-T130 PolarHBondContact NH2-OG1 2.83Å; S128-T130 PolarHBondContact O-N 2.99Å; S128-T130 PolarHBondContact OG-N 2.73Å; S128-T130 PolarHBondContact OG-O 2.81Å; S128-T130 PolarHBondContact OG-OG1 2.9Å; T130-S132 PolarHBondContact O-N 3.32Å
131A39.4Very low75.6Confident104 Ų10470.5 Ų70.586%0.8643%0.425SS*.  trans-66.230.6-171.700000116.9K133A131-K133 VanDerWaalsContact C-N 3.32Å; A131-K133 PolarHBondContact O-N 2.81Å
132S43.9Very low75.9Confident83 Ų8369.3 Ų69.358%0.5842%0.417SS*.  trans-77.879.3171.4-530000110.4T130 G134T130-S132 PolarHBondContact O-N 3.32Å; S132-G134 PolarHBondContact O-N 2.92Å
133K38.6Very low75.9Confident212 Ų21264.1 Ų64.192%0.92239%0.394SS*.THydrogen-bonded Turntrans-58.3123.6175.3-73.3-177.9176.31780111A131A131-K133 VanDerWaalsContact C-N 3.32Å; A131-K133 PolarHBondContact O-N 2.81Å
134G47.2Very low75.9Confident85 Ų8558.9 Ų58.988%0.87637%0.369SS*.THydrogen-bonded Turntrans111.2-4.8154.900000118.8S132S132-G134 PolarHBondContact O-N 2.92Å
135K58.2Low75.8Confident171 Ų17157.9 Ų57.974%0.74337%0.365SS*.  trans-99.6124.4176.6-159.6171.7-175.5178.70110.5I137K135-I137 PolarHBondContact O-N 3.42Å
136S65.8Low75.9Confident99 Ų9954.6 Ų54.669%0.69234%0.338SS*.  trans-60.9120.3171.8177.30000109.6
137I82Confident75.7Confident31 Ų3156.7 Ų56.716%0.15935%0.348CS..  trans-102.613.8-179.950.2159.9000112.9G32 L126 K135G32-I137 PolarHBondContact N-O 2.92Å; L126-I137 HydrophobicContact CB-CD1 3.71Å; L126-I137 HydrophobicContact CB-CG1 3.81Å; L126-I137 WeakPolarHBondContact O-CG1 3.29Å; K135-I137 PolarHBondContact O-N 3.42Å
138G89.2Confident75.3Confident1 Ų156.3 Ų56.31%0.0135%0.354CS..  trans101.6178.8-179.300000113.8T29 K30 L126T29-G138 CarbonylContact O-C 3.58Å; T29-G138 VanDerWaalsContact O-CA 3.23Å; T29-G138 WeakPolarHBondContact O-CA 3.18Å; K30-G138 WeakPolarHBondContact O-CA 3.43Å; K30-G138 PolarHBondContact O-N 2.84Å; L126-G138 WeakPolarHBondContact CB-O 3.39Å; L126-G138 PolarHBondContact N-O 2.89Å
139S93.7Very high74.9Confident9 Ų960 Ų606%0.06338%0.38CS..EExtended strand (participates in β ladder)trans-139.3151.8-176.5-48.70000111.2G28 T29 E123 Y124G28-S139 CarbonylContact C-O 3.45Å; G28-S139 WeakPolarHBondContact CA-O 3.42Å; T29-S139 PolarHBondContact N-O 2.93Å; T29-S139 PolarHBondContact O-N 3.18Å; E123-S139 VanDerWaalsContact CG-CB 3.48Å; E123-S139 WeakPolarHBondContact OE1-CB 3.5Å; E123-S139 PolarHBondContact OE1-OG 3.29Å; Y124-S139 CarbonylContact O-C 3.46Å; Y124-S139 WeakPolarHBondContact O-CA 3.4Å; Y124-S139 WeakPolarHBondContact O-CB 3.46Å
140L96.9Very high74.4Confident0 Ų062.5 Ų62.50%039%0.388CS..EExtended strand (participates in β ladder)trans-107.4144.6168.5-65.8-179.1000110.7L25 W72 I88 V90 V105 Y124 L126 L142L25-L140 HydrophobicContact CD1-CD2 4.41Å; W72-L140 HydrophobicContact CH2-CD2 4.34Å; W72-L140 HydrophobicContact CZ3-CD2 3.94Å; I88-L140 HydrophobicContact CB-CD1 4.21Å; I88-L140 HydrophobicContact CG2-CD1 3.59Å; V90-L140 HydrophobicContact CG2-CD1 3.72Å; V90-L140 HydrophobicContact CG2-CD2 3.97Å; V90-L140 HydrophobicContact CG2-CG 4.11Å; V105-L140 HydrophobicContact CG2-CB 4.31Å; V105-L140 HydrophobicContact CG2-CD1 4.03Å; V105-L140 HydrophobicContact CG2-CG 4.37Å; Y124-L140 PolarHBondContact N-O 3.03Å; Y124-L140 PolarHBondContact O-N 2.77Å; L126-L140 HydrophobicContact CD2-CD1 4.17Å; L126-L140 HydrophobicContact CD2-CG 4.08Å; L140-L142 HydrophobicContact CB-CD1 4.01Å; L140-L142 HydrophobicContact CB-CD2 4.1Å; L140-L142 HydrophobicContact CB-CG 3.83Å; L140-L142 HydrophobicContact CD1-CD1 4.26Å; L140-L142 HydrophobicContact CD1-CD2 4.42Å
141F96.8Very high73.5Confident33 Ų3364.3 Ų64.315%0.14540%0.404CS..EExtended strand (participates in β ladder)trans-98.3108171.2-76.3-102.1000109.3L26 R27 T29 P121 E122 E123L26-F141 HydrophobicContact CB-CB 4.12Å; L26-F141 WeakPolarHBondContact CB-O 3.36Å; L26-F141 HydrophobicContact CD2-CB 4.34Å; L26-F141 PolarHBondContact N-O 3.32Å; R27-F141 HydrophobicContact CG-CB 3.92Å; R27-F141 HydrophobicContact CG-CD2 3.85Å; R27-F141 HydrophobicContact CG-CG 4.03Å; R27-F141 VanDerWaalsContact NH2-CZ 3.31Å; R27-F141 PolarHBondContact O-N 3.4Å; T29-F141 HydrophobicContact CG2-CD2 3.95Å; T29-F141 HydrophobicContact CG2-CE2 3.49Å; T29-F141 VanDerWaalsContact CG2-CE2 3.49Å; P121-F141 HydrophobicContact CB-CB 4.28Å; E122-F141 CarbonylContact O-C 3.55Å; E122-F141 VanDerWaalsContact O-CA 3.27Å; E122-F141 WeakPolarHBondContact O-CA 3.24Å; E123-F141 HydrophobicContact CB-CD1 4.49Å; E123-F141 HydrophobicContact CB-CE1 3.99Å; E123-F141 HydrophobicContact CB-CE2 4.38Å; E123-F141 HydrophobicContact CB-CZ 3.91Å; E123-F141 HydrophobicContact CG-CE2 4.06Å; E123-F141 HydrophobicContact CG-CZ 3.95Å
142L96.4Very high73Confident1 Ų166.1 Ų66.11%0.00540%0.399CS..EExtended strand (participates in β ladder)trans-129.9149.5-170.2-54.7173.7000111.1R24 L25 I88 V105 P121 E122 Y124 L140 F144R24-L142 VanDerWaalsContact O-CA 3.3Å; R24-L142 WeakPolarHBondContact O-CA 3.27Å; L25-L142 HydrophobicContact CB-CD2 4.2Å; L25-L142 HydrophobicContact CD1-CD2 3.39Å; L25-L142 HydrophobicContact CG-CD2 4.39Å; I88-L142 HydrophobicContact CD1-CD1 4.02Å; I88-L142 HydrophobicContact CG1-CD1 4.27Å; V105-L142 HydrophobicContact CB-CD1 4.12Å; V105-L142 HydrophobicContact CG1-CD1 3.98Å; V105-L142 HydrophobicContact CG2-CD1 4.21Å; P121-L142 CarbonylContact C-O 3.57Å; P121-L142 WeakPolarHBondContact CA-O 3.18Å; E122-L142 PolarHBondContact N-O 3.16Å; E122-L142 PolarHBondContact O-N 3.42Å; Y124-L142 HydrophobicContact CD2-CB 3.79Å; Y124-L142 HydrophobicContact CD2-CD1 4.21Å; Y124-L142 HydrophobicContact CD2-CG 4.22Å; Y124-L142 HydrophobicContact CE2-CB 3.94Å; Y124-L142 HydrophobicContact CG-CD1 4.3Å; L140-L142 HydrophobicContact CB-CD1 4.01Å; L140-L142 HydrophobicContact CB-CD2 4.1Å; L140-L142 HydrophobicContact CB-CG 3.83Å; L140-L142 HydrophobicContact CD1-CD1 4.26Å; L140-L142 HydrophobicContact CD1-CD2 4.42Å; L142-F144 HydrophobicContact CB-CE2 3.86Å; L142-F144 HydrophobicContact CB-CZ 4.22Å; L142-F144 HydrophobicContact CD1-CE2 4.27Å; L142-F144 HydrophobicContact CD1-CZ 4.07Å
143S93.8Very high72.2Confident5 Ų569.7 Ų69.74%0.03541%0.411CS..EExtended strand (participates in β ladder)trans-133.4140.7164.368.50000110.8R24R24-S143 WeakPolarHBondContact CB-OG 3.46Å; R24-S143 PolarHBondContact N-O 2.65Å; R24-S143 PolarHBondContact O-N 3.48Å; R24-S143 VanDerWaalsContact O-N 3.1Å
144F94.5Very high71.4Confident8 Ų864.5 Ų64.54%0.03540%0.402CS..EExtended strand (participates in β ladder)trans-121131.9175.7-55.8-91.1000108.1L21 R22 V23 M86 I88 R107 I114 Y124 L142L21-F144 HydrophobicContact CD1-CB 4.31Å; L21-F144 HydrophobicContact CD2-CD1 4.41Å; R22-F144 WeakPolarHBondContact O-CA 3.18Å; V23-F144 HydrophobicContact CB-CD1 4.47Å; V23-F144 HydrophobicContact CB-CE1 4.47Å; V23-F144 HydrophobicContact CG1-CD1 4.13Å; V23-F144 HydrophobicContact CG1-CE1 3.72Å; V23-F144 HydrophobicContact CG1-CZ 4.44Å; V23-F144 HydrophobicContact CG2-CD1 3.92Å; V23-F144 HydrophobicContact CG2-CE1 4.08Å; M86-F144 HydrophobicContact CB-CE1 4.47Å; M86-F144 HydrophobicContact CG-CE1 3.88Å; I88-F144 HydrophobicContact CD1-CE1 4.07Å; I88-F144 HydrophobicContact CD1-CZ 3.72Å; R107-F144 HydrophobicContact CB-CE2 4.5Å; R107-F144 HydrophobicContact CB-CZ 4.33Å; R107-F144 HydrophobicContact CG-CD2 4.47Å; R107-F144 HydrophobicContact CG-CE2 4.45Å; I114-F144 HydrophobicContact CD1-CB 4.15Å; I114-F144 HydrophobicContact CG1-CB 4.34Å; I114-F144 HydrophobicContact CG2-CB 4.06Å; Y124-F144 HydrophobicContact CE1-CE2 4.4Å; Y124-F144 HydrophobicContact CE2-CE2 4.29Å; L142-F144 HydrophobicContact CB-CE2 3.86Å; L142-F144 HydrophobicContact CB-CZ 4.22Å; L142-F144 HydrophobicContact CD1-CE2 4.27Å; L142-F144 HydrophobicContact CD1-CZ 4.07Å
145H92Very high70.7Confident15 Ų1565.9 Ų65.97%0.06940%0.395CS..EExtended strand (participates in β ladder)trans-149.7145167.762.2-77.6000110.9R22 T115R22-H145 WeakPolarHBondContact CD-CE1 3.45Å; R22-H145 PolarHBondContact N-O 3.13Å; R22-H145 PolarHBondContact O-N 2.93Å; R22-H145 VanDerWaalsContact O-N 3.12Å; T115-H145 CarbonylContact O-C 3.14Å; T115-H145 VanDerWaalsContact O-CA 3.23Å; T115-H145 WeakPolarHBondContact O-CA 3.49Å; T115-H145 VanDerWaalsContact O-CB 3.28Å; T115-H145 WeakPolarHBondContact O-CB 3.3Å
146F92.5Very high69.1Low1 Ų162.7 Ų62.70%0.00439%0.394CS..EExtended strand (participates in β ladder)trans-76.5134.3171.9-73-76.7000109.6E19 L20 L21 V80 R82 L109 I114 T115 T116E19-F146 HydrophobicContact CB-CD1 3.8Å; E19-F146 HydrophobicContact CB-CE1 4.03Å; L20-F146 CarbonylContact O-C 3.44Å; L20-F146 WeakPolarHBondContact O-CA 3.42Å; L21-F146 HydrophobicContact CB-CD1 4.35Å; L21-F146 HydrophobicContact CB-CE1 4.17Å; L21-F146 HydrophobicContact CD1-CD1 4.15Å; L21-F146 HydrophobicContact CD1-CD2 4.38Å; L21-F146 HydrophobicContact CD1-CE1 3.97Å; L21-F146 HydrophobicContact CD1-CE2 4.18Å; L21-F146 HydrophobicContact CD1-CG 4.36Å; L21-F146 HydrophobicContact CD1-CZ 3.99Å; V80-F146 HydrophobicContact CG2-CE1 3.76Å; V80-F146 HydrophobicContact CG2-CZ 4.47Å; R82-F146 VanDerWaalsContact CZ-CZ 3.45Å; L109-F146 HydrophobicContact CB-CZ 4.45Å; I114-F146 HydrophobicContact CB-CD2 4.06Å; I114-F146 HydrophobicContact CB-CE2 3.78Å; I114-F146 HydrophobicContact CD1-CE2 4.38Å; I114-F146 HydrophobicContact CG2-CD2 3.52Å; I114-F146 HydrophobicContact CG2-CE2 3.57Å; T115-F146 PolarHBondContact O-N 2.87Å; T116-F146 VanDerWaalsContact CA-O 3.24Å; T116-F146 WeakPolarHBondContact CA-O 3.39Å; T116-F146 HydrophobicContact CG2-CB 4.31Å
147M87.2Confident67.1Low60 Ų6064.2 Ų64.230%0.29640%0.395SS..PPolyproline II helixtrans-74136.2172.1-64.6-176.259.800108.8L20 R22 T77 S149L20-M147 HydrophobicContact CB-CB 4.1Å; L20-M147 HydrophobicContact CB-CG 4.35Å; L20-M147 HydrophobicContact CB-SD 4.29Å; L20-M147 HydrophobicContact CD1-SD 4.47Å; L20-M147 PolarHBondContact O-N 3.36Å; R22-M147 HydrophobicContact CB-CG 4.32Å; T77-M147 HydrophobicContact CG2-SD 3.99Å; M147-S149 PolarHBondContact O-N 3.28Å
148P81.2Confident64.4Low95 Ų9568.8 Ų68.862%0.61743%0.43SS*.PPolyproline II helixtrans-59.5134.2171.219.3-23.5000109S150P148-S150 PolarHBondContact O-N 3.15Å
149S68Low61.3Low120 Ų12073.8 Ų73.884%0.83946%0.46SS*.  trans-61.697.9170.553.40000108.2M147 S151M147-S149 PolarHBondContact O-N 3.28Å; S149-S151 PolarHBondContact O-N 2.9Å
150S52.9Low58Low114 Ų11477.6 Ų77.680%0.79749%0.492SS*.  trans-70.5101.4178.5480000109.5P148P148-S150 PolarHBondContact O-N 3.15Å
151S34Very low54.5Low104 Ų10485.2 Ų85.273%0.72753%0.533SS*.  trans-61.1123146.650.10000108.8S149S149-S151 PolarHBondContact O-N 2.9Å
152D28Very low51.3Low141 Ų14192.2 Ų92.275%0.75457%0.571SS**SBendtrans41.7104.8157.3-60.6-25.8000119.4
153N27.4Very low47.9Very low158 Ų158101.3 Ų101.385%0.84561%0.613SS**  162.6105.6117.2-86-33.2000112.9
154S21.9Very low44.6Very low104 Ų104110.2 Ų110.273%0.72765%0.654SS**  trans-54.6150.5141.643.50000110.9
155P32.3Very low41.5Very low113 Ų113116.5 Ų116.573%0.73469%0.694SS**  -155171.25939.9-17.9000119.1
156S24.2Very low38.5Very low104 Ų104121.1 Ų121.173%0.72773%0.727SS**  trans63.4110.914461.70000120.2
157D24.2Very low35.9Very low132 Ų132125.3 Ų125.371%0.70676%0.757SS**  91.211660.9-157.124.5000112.1
158S25.7Very low34Very low127 Ų127127 Ų12789%0.88879%0.789SS**  trans-172.199161.6-76.70000109
159T23.4Very low33.1Very low106 Ų106125 Ų12565%0.6577%0.772SS**  trans-77.1141.8172.743.30000112.6
160A24.9Very low33Very low89 Ų89122 Ų12274%0.73675%0.751SS**  trans-149.5118.3152.700000110.8
161D23.8Very low33.5Very low160 Ų160126.2 Ų126.286%0.85676%0.758SS**  trans49.8103.7145.5-54.2-24.9000121
162L29.9Very low35Very low179 Ų179122.7 Ų122.794%0.93774%0.738SS**  trans-126.7123.4153.9-87.7164.7000109.8
163Q24.3Very low37Very low192 Ų192118.5 Ų118.590%0.89771%0.711SS**  trans-66.9140.9-179.2-81.8164.8-3100112.3
164Q24.5Very low39.5Very low193 Ų193114 Ų11490%0.90269%0.685SS**  trans-58125.8171.3-77164.7-37.900111.8
165T28.9Very low41.9Very low140 Ų140113.9 Ų113.986%0.85967%0.673SS**  trans-92.4109.4155.852.60000108.3S167T165-S167 PolarHBondContact O-N 3.43Å
166S29.1Very low44.1Very low111 Ų111114.9 Ų114.978%0.77666%0.662SS**  trans-84.595178.745.80000111.3
167S39.1Very low45.9Very low90 Ų90116.4 Ų116.463%0.62966%0.658SS**  trans-164.9121.6151.3-17.40000108T165 M169T165-S167 PolarHBondContact O-N 3.43Å; S167-M169 PolarHBondContact O-N 3.43Å
168G46.5Very low47.8Very low94 Ų94112.6 Ų112.697%0.96964%0.638SS**  trans-73.252.5-178.300000113.7
169M63.1Low48.9Very low53 Ų53110.8 Ų110.826%0.26164%0.639SS.*PPolyproline II helixtrans-83.3138.8179-76.2-80.6-87.500111S167 W173 E175 Y185S167-M169 PolarHBondContact O-N 3.43Å; M169-W173 HydrophobicContact CE-CB 3.59Å; M169-W173 HydrophobicContact SD-CB 4.41Å; M169-E175 HydrophobicContact CE-CB 4.14Å; M169-Y185 HydrophobicContact CE-CD1 3.92Å; M169-Y185 HydrophobicContact SD-CD1 4.31Å
170P64.2Low50.4Low59 Ų59111.9 Ų111.938%0.38364%0.641SS.*PPolyproline II helixtrans-62151173.6-18.130000111.9G172 W173 P198P170-G172 PolarHBondContact O-N 2.89Å; P170-W173 WeakPolarHBondContact O-CB 3.47Å; P170-W173 PolarHBondContact O-N 3.05Å; P170-W173 VanDerWaalsContact O-N 3.07Å; P170-P198 HydrophobicContact CG-CG 4.4Å
171Q63.6Low51.6Low202 Ų202110 Ų11094%0.94463%0.63SS**THydrogen-bonded Turntrans-58.3128.8-179.9-172.5173.17.400111.1
172G65.4Low53.2Low30 Ų30109.7 Ų109.731%0.30962%0.617SS.*THydrogen-bonded Turntrans93.4-0.5-176.200000114.6P170 N187 H188P170-G172 PolarHBondContact O-N 2.89Å; G172-N187 CarbonylContact O-C 3.51Å; G172-H188 WeakPolarHBondContact O-CB 3.39Å; G172-H188 PolarHBondContact O-N 3Å
173W71.5Confident55.1Low52 Ų52103.4 Ų103.420%0.19759%0.586CS.*EExtended strand (participates in β ladder)trans-103.5141.5173-69.282.3000112.5M169 P170 V186 N187 Q194 P198M169-W173 HydrophobicContact CE-CB 3.59Å; M169-W173 HydrophobicContact SD-CB 4.41Å; P170-W173 WeakPolarHBondContact O-CB 3.47Å; P170-W173 PolarHBondContact O-N 3.05Å; P170-W173 VanDerWaalsContact O-N 3.07Å; W173-V186 CarbonylContact C-O 3.59Å; W173-V186 WeakPolarHBondContact CA-O 3.33Å; W173-N187 HydrophobicContact CD2-CB 3.82Å; W173-N187 HydrophobicContact CE3-CB 3.75Å; W173-N187 HydrophobicContact CH2-CB 3.73Å; W173-N187 HydrophobicContact CZ2-CB 3.79Å; W173-N187 WeakPolarHBondContact CZ2-ND2 3.21Å; W173-N187 HydrophobicContact CZ3-CB 3.7Å; W173-N187 PolarHBondContact NE1-ND2 2.84Å; W173-Q194 HydrophobicContact CH2-CG 4.28Å; W173-Q194 HydrophobicContact CZ3-CG 3.92Å; W173-P198 HydrophobicContact CD2-CB 4.23Å; W173-P198 HydrophobicContact CD2-CG 3.87Å; W173-P198 HydrophobicContact CE3-CB 4.46Å; W173-P198 HydrophobicContact CE3-CG 4.02Å; W173-P198 HydrophobicContact CG-CG 4.27Å; W173-P198 HydrophobicContact CH2-CB 4.09Å; W173-P198 HydrophobicContact CZ2-CB 3.83Å; W173-P198 HydrophobicContact CZ2-CG 4.38Å; W173-P198 HydrophobicContact CZ3-CB 4.4Å; W173-P198 HydrophobicContact CZ3-CG 4.35Å
174E78.5Confident57.3Low65 Ų6595 Ų9530%0.30455%0.548SS..EExtended strand (participates in β ladder)trans-128.4142.9174.6177.7-171.8159.200108.9R176 Y185 V186 H188E174-R176 IonicContact OE1-CZ 2.75Å; E174-R176 IonicContact OE1-NE 3.65Å; E174-R176 PolarHBondContact OE1-NE 2.84Å; E174-R176 VanDerWaalsContact OE1-NE 3.15Å; E174-R176 IonicContact OE1-NH2 2.81Å; E174-R176 PolarHBondContact OE1-NH2 3.09Å; E174-R176 IonicContact OE2-NH2 2.6Å; E174-R176 PolarHBondContact OE2-NH2 2.98Å; E174-Y185 CarbonylContact O-C 3.57Å; E174-Y185 WeakPolarHBondContact O-CA 3.27Å; E174-V186 HydrophobicContact CB-CB 4.3Å; E174-V186 PolarHBondContact N-O 3.41Å; E174-V186 PolarHBondContact O-N 3.23Å; E174-H188 WeakPolarHBondContact CB-NE2 3.21Å; E174-H188 IonicContact OE2-CD2 3.83Å; E174-H188 IonicContact OE2-CE1 2.94Å; E174-H188 PolarHBondContact OE2-CE1 2.84Å; E174-H188 IonicContact OE2-NE2 2.6Å; E174-H188 PolarHBondContact OE2-NE2 3.14Å
175E73.6Confident59.7Low101 Ų10187.3 Ų87.347%0.47251%0.511SS..EExtended strand (participates in β ladder)trans-102.5135.4171.8-177.6175.8165.700109M169 T183 Y185M169-E175 HydrophobicContact CE-CB 4.14Å; E175-T183 HydrophobicContact CG-CG2 3.51Å; E175-T183 WeakPolarHBondContact OE1-CG2 3.47Å; E175-Y185 HydrophobicContact CB-CD1 4.09Å; E175-Y185 HydrophobicContact CB-CE1 4.11Å; E175-Y185 HydrophobicContact CG-CD1 4.02Å; E175-Y185 HydrophobicContact CG-CE1 3.66Å
176R77.8Confident61.6Low134 Ų13481.7 Ų81.751%0.50648%0.476SS..EExtended strand (participates in β ladder)trans-142.3157.5-178.4-162.9178-71.9178.5-1.3110.6E174 T183 V184 V186E174-R176 IonicContact OE1-CZ 2.75Å; E174-R176 IonicContact OE1-NE 3.65Å; E174-R176 PolarHBondContact OE1-NE 2.84Å; E174-R176 VanDerWaalsContact OE1-NE 3.15Å; E174-R176 IonicContact OE1-NH2 2.81Å; E174-R176 PolarHBondContact OE1-NH2 3.09Å; E174-R176 IonicContact OE2-NH2 2.6Å; E174-R176 PolarHBondContact OE2-NH2 2.98Å; R176-T183 CarbonylContact O-C 3.56Å; R176-T183 WeakPolarHBondContact O-CA 3.48Å; R176-V184 PolarHBondContact N-O 2.85Å; R176-V184 PolarHBondContact O-N 3.5Å; R176-V184 VanDerWaalsContact O-O 3.13Å; R176-V186 HydrophobicContact CB-CG2 4.34Å
177E61.3Low63.5Low136 Ų13676.9 Ų76.964%0.63644%0.442SS*.EExtended strand (participates in β ladder)trans-101.8138.1168.6-68.1178.9177.700110.4R182E177-R182 CarbonylContact C-O 3.54Å; E177-R182 VanDerWaalsContact CA-O 3.32Å; E177-R182 WeakPolarHBondContact CA-O 3.33Å
178D64.6Low64.4Low52 Ų5277.2 Ų77.228%0.27843%0.433SS..  trans-78174.8172.373.410.4000112.1N180 G181 R182 V184D178-N180 PolarHBondContact O-N 3.44Å; D178-N180 WeakPolarHBondContact OD1-CA 3.5Å; D178-N180 PolarHBondContact OD1-N 2.93Å; D178-G181 PolarHBondContact O-N 2.91Å; D178-G181 PolarHBondContact OD1-N 3.47Å; D178-G181 VanDerWaalsContact OD1-N 3.16Å; D178-R182 PolarHBondContact N-O 3.44Å; D178-R182 WeakPolarHBondContact OD1-CB 3.42Å; D178-R182 PolarHBondContact OD1-N 3.28Å; D178-V184 HydrophobicContact CB-CG2 4.13Å
179G49.2Very low65Low89 Ų8976.8 Ų76.892%0.91842%0.42SS*.THydrogen-bonded Turntrans-62.2-9.8-179.900000115.1
180N55Low64.6Low129 Ų12978.3 Ų78.369%0.6943%0.429SS*.THydrogen-bonded Turntrans-105.19.1175.6-65.9-21.2000112.3D178D178-N180 PolarHBondContact O-N 3.44Å; D178-N180 WeakPolarHBondContact OD1-CA 3.5Å; D178-N180 PolarHBondContact OD1-N 2.93Å
181G48.8Very low64Low49 Ų4984.6 Ų84.651%0.50545%0.445SS..SBendtrans75.619.3179.400000114.6D178D178-G181 PolarHBondContact O-N 2.91Å; D178-G181 PolarHBondContact OD1-N 3.47Å; D178-G181 VanDerWaalsContact OD1-N 3.16Å
182R57.5Low63.7Low153 Ų15376.3 Ų76.358%0.57741%0.408SS*.  trans-92.8136.3177.6-54.4179-171.1-178.54.3110.5E177 D178E177-R182 CarbonylContact C-O 3.54Å; E177-R182 VanDerWaalsContact CA-O 3.32Å; E177-R182 WeakPolarHBondContact CA-O 3.33Å; D178-R182 PolarHBondContact N-O 3.44Å; D178-R182 WeakPolarHBondContact OD1-CB 3.42Å; D178-R182 PolarHBondContact OD1-N 3.28Å
183T70Confident63.8Low48 Ų4879.4 Ų79.429%0.29442%0.422SS..EExtended strand (participates in β ladder)trans-71.1128.4177.2-460000111.6E175 R176 Y185E175-T183 HydrophobicContact CG-CG2 3.51Å; E175-T183 WeakPolarHBondContact OE1-CG2 3.47Å; R176-T183 CarbonylContact O-C 3.56Å; R176-T183 WeakPolarHBondContact O-CA 3.48Å; T183-Y185 HydrophobicContact CG2-CE1 4.25Å; T183-Y185 HydrophobicContact CG2-CE2 4.08Å
184V70.7Confident63.6Low16 Ų1679.9 Ų79.910%0.09743%0.426CS..EExtended strand (participates in β ladder)trans-127126.8-178.7-1780000108.8R176 D178 V186 T193 Q194 F195R176-V184 PolarHBondContact N-O 2.85Å; R176-V184 PolarHBondContact O-N 3.5Å; R176-V184 VanDerWaalsContact O-O 3.13Å; D178-V184 HydrophobicContact CB-CG2 4.13Å; V184-V186 HydrophobicContact CG1-CG2 4.5Å; V184-T193 HydrophobicContact CG1-CG2 4.09Å; V184-Q194 CarbonylContact C-O 3.55Å; V184-F195 HydrophobicContact CG2-CD1 3.88Å; V184-F195 HydrophobicContact CG2-CE1 3.55Å; V184-F195 HydrophobicContact CG2-CZ 4.35Å
185Y76.4Confident63.4Low31 Ų3183.2 Ų83.212%0.12244%0.44CS..EExtended strand (participates in β ladder)trans-96.9117.3176.5-56.9-82.7000109.6M169 E174 E175 T183 T193 Q194 T196 P197M169-Y185 HydrophobicContact CE-CD1 3.92Å; M169-Y185 HydrophobicContact SD-CD1 4.31Å; E174-Y185 CarbonylContact O-C 3.57Å; E174-Y185 WeakPolarHBondContact O-CA 3.27Å; E175-Y185 HydrophobicContact CB-CD1 4.09Å; E175-Y185 HydrophobicContact CB-CE1 4.11Å; E175-Y185 HydrophobicContact CG-CD1 4.02Å; E175-Y185 HydrophobicContact CG-CE1 3.66Å; T183-Y185 HydrophobicContact CG2-CE1 4.25Å; T183-Y185 HydrophobicContact CG2-CE2 4.08Å; Y185-T193 CarbonylContact O-C 3.59Å; Y185-T193 WeakPolarHBondContact O-CA 3.42Å; Y185-Q194 PolarHBondContact N-O 3.48Å; Y185-Q194 PolarHBondContact O-N 2.91Å; Y185-T196 VanDerWaalsContact CD2-C 3.46Å; Y185-T196 WeakPolarHBondContact CD2-O 3.37Å; Y185-P197 HydrophobicContact CE1-CB 4.4Å; Y185-P197 HydrophobicContact CE1-CG 4.49Å; Y185-P197 HydrophobicContact CE2-CB 4.23Å; Y185-P197 HydrophobicContact CE2-CG 3.78Å
186V67.2Low63.1Low22 Ų2283.2 Ų83.213%0.13345%0.446CS..EExtended strand (participates in β ladder)trans-101.9116.9-175.3-172.40000109.6W173 E174 R176 V184 T192 T193W173-V186 CarbonylContact C-O 3.59Å; W173-V186 WeakPolarHBondContact CA-O 3.33Å; E174-V186 HydrophobicContact CB-CB 4.3Å; E174-V186 PolarHBondContact N-O 3.41Å; E174-V186 PolarHBondContact O-N 3.23Å; R176-V186 HydrophobicContact CB-CG2 4.34Å; V184-V186 HydrophobicContact CG1-CG2 4.5Å; V186-T192 CarbonylContact C-O 3.57Å; V186-T192 WeakPolarHBondContact CA-O 3.41Å; V186-T193 HydrophobicContact CB-CG2 4.27Å; V186-T193 HydrophobicContact CG1-CG2 4.08Å; V186-T193 HydrophobicContact CG2-CG2 3.9Å
187N69.9Low62.7Low9 Ų980.7 Ų80.75%0.04845%0.448CS..EExtended strand (participates in β ladder)trans-93.5109.9171.4-174.6-33.4000109.5G172 W173 A189 L190 R191 T192G172-N187 CarbonylContact O-C 3.51Å; W173-N187 HydrophobicContact CD2-CB 3.82Å; W173-N187 HydrophobicContact CE3-CB 3.75Å; W173-N187 HydrophobicContact CH2-CB 3.73Å; W173-N187 HydrophobicContact CZ2-CB 3.79Å; W173-N187 WeakPolarHBondContact CZ2-ND2 3.21Å; W173-N187 HydrophobicContact CZ3-CB 3.7Å; W173-N187 PolarHBondContact NE1-ND2 2.84Å; N187-A189 WeakPolarHBondContact OD1-CA 3.41Å; N187-A189 WeakPolarHBondContact OD1-CB 3.24Å; N187-A189 PolarHBondContact OD1-N 3.1Å; N187-L190 HydrophobicContact CB-CB 4.42Å; N187-L190 PolarHBondContact OD1-N 3.2Å; N187-R191 CarbonylContact O-C 3.49Å; N187-R191 WeakPolarHBondContact O-CA 3.42Å; N187-R191 PolarHBondContact O-N 2.99Å; N187-T192 PolarHBondContact N-O 3.11Å; N187-T192 PolarHBondContact O-N 3Å; N187-T192 VanDerWaalsContact O-N 3.08Å
188H58.4Low62.9Low98 Ų9875.5 Ų75.545%0.45443%0.425SS..THydrogen-bonded Turntrans-71.9-28.4179.5-71-81.4000113.8G172 E174G172-H188 WeakPolarHBondContact O-CB 3.39Å; G172-H188 PolarHBondContact O-N 3Å; E174-H188 WeakPolarHBondContact CB-NE2 3.21Å; E174-H188 IonicContact OE2-CD2 3.83Å; E174-H188 IonicContact OE2-CE1 2.94Å; E174-H188 PolarHBondContact OE2-CE1 2.84Å; E174-H188 IonicContact OE2-NE2 2.6Å; E174-H188 PolarHBondContact OE2-NE2 3.14Å
189A57.7Low62.6Low84 Ų8481.6 Ų81.669%0.69445%0.452SS*.THydrogen-bonded Turntrans-73.7-42.1179.200000111.4N187N187-A189 WeakPolarHBondContact OD1-CA 3.41Å; N187-A189 WeakPolarHBondContact OD1-CB 3.24Å; N187-A189 PolarHBondContact OD1-N 3.1Å
190L56Low62.5Low86 Ų8682.7 Ų82.745%0.4545%0.446SS..THydrogen-bonded Turntrans-91.8-9176.7-60.9179.6000113.4N187 T192 V214N187-L190 HydrophobicContact CB-CB 4.42Å; N187-L190 PolarHBondContact OD1-N 3.2Å; L190-T192 VanDerWaalsContact C-N 3.3Å; L190-T192 HydrophobicContact CB-CG2 4.06Å; L190-T192 PolarHBondContact O-N 3.37Å; L190-V214 HydrophobicContact CD2-CG2 4.09Å
191R51.9Low61.8Low190 Ų19082.6 Ų82.672%0.71745%0.45SS*.THydrogen-bonded Turntrans51.346.6-173-57.5-175.2-180-158.71.4112.5N187N187-R191 CarbonylContact O-C 3.49Å; N187-R191 WeakPolarHBondContact O-CA 3.42Å; N187-R191 PolarHBondContact O-N 2.99Å
192T56Low61Low28 Ų2885.4 Ų85.417%0.17246%0.462CS..EExtended strand (participates in β ladder)trans-117.4158.4179.358.90000111.6V186 N187 L190V186-T192 CarbonylContact C-O 3.57Å; V186-T192 WeakPolarHBondContact CA-O 3.41Å; N187-T192 PolarHBondContact N-O 3.11Å; N187-T192 PolarHBondContact O-N 3Å; N187-T192 VanDerWaalsContact O-N 3.08Å; L190-T192 VanDerWaalsContact C-N 3.3Å; L190-T192 HydrophobicContact CB-CG2 4.06Å; L190-T192 PolarHBondContact O-N 3.37Å
193T66.9Low59.6Low96 Ų9686.3 Ų86.359%0.58948%0.478SS*.EExtended strand (participates in β ladder)trans-125.9141.6170.553.70000109.4V184 Y185 V186V184-T193 HydrophobicContact CG1-CG2 4.09Å; Y185-T193 CarbonylContact O-C 3.59Å; Y185-T193 WeakPolarHBondContact O-CA 3.42Å; V186-T193 HydrophobicContact CB-CG2 4.27Å; V186-T193 HydrophobicContact CG1-CG2 4.08Å; V186-T193 HydrophobicContact CG2-CG2 3.9Å
194Q68.8Low57.7Low61 Ų6187 Ų8729%0.28550%0.495SS..EExtended strand (participates in β ladder)trans-144.5156.2177.862.5-17737.200110.5W173 V184 Y185 T196W173-Q194 HydrophobicContact CH2-CG 4.28Å; W173-Q194 HydrophobicContact CZ3-CG 3.92Å; V184-Q194 CarbonylContact C-O 3.55Å; Y185-Q194 PolarHBondContact N-O 3.48Å; Y185-Q194 PolarHBondContact O-N 2.91Å; Q194-T196 WeakPolarHBondContact CG-O 3.2Å; Q194-T196 PolarHBondContact NE2-O 2.8Å
195F74.2Confident55.7Low136 Ų13693.1 Ų93.160%0.59653%0.527SS*.SBendtrans-92.5-10.1-179-64-82000113.5V184V184-F195 HydrophobicContact CG2-CD1 3.88Å; V184-F195 HydrophobicContact CG2-CE1 3.55Å; V184-F195 HydrophobicContact CG2-CZ 4.35Å
196T66Low53.8Low100 Ų10097.9 Ų97.961%0.61356%0.559SS**SBendtrans-103.314117724.90000111.4Y185 Q194Y185-T196 VanDerWaalsContact CD2-C 3.46Å; Y185-T196 WeakPolarHBondContact CD2-O 3.37Å; Q194-T196 WeakPolarHBondContact CG-O 3.2Å; Q194-T196 PolarHBondContact NE2-O 2.8Å
197P70.1Confident52.3Low82 Ų82104.5 Ų104.553%0.53259%0.594SS.*PPolyproline II helixtrans-62.4144.4176.8-17.327.3000111.9Y185Y185-P197 HydrophobicContact CE1-CB 4.4Å; Y185-P197 HydrophobicContact CE1-CG 4.49Å; Y185-P197 HydrophobicContact CE2-CB 4.23Å; Y185-P197 HydrophobicContact CE2-CG 3.78Å
198P65.4Low50.7Low26 Ų26107.5 Ų107.517%0.16962%0.62CS.*PPolyproline II helixtrans-65.2136.5174.726.2-32.7000111.7P170 W173 S200P170-P198 HydrophobicContact CG-CG 4.4Å; W173-P198 HydrophobicContact CD2-CB 4.23Å; W173-P198 HydrophobicContact CD2-CG 3.87Å; W173-P198 HydrophobicContact CE3-CB 4.46Å; W173-P198 HydrophobicContact CE3-CG 4.02Å; W173-P198 HydrophobicContact CG-CG 4.27Å; W173-P198 HydrophobicContact CH2-CB 4.09Å; W173-P198 HydrophobicContact CZ2-CB 3.83Å; W173-P198 HydrophobicContact CZ2-CG 4.38Å; W173-P198 HydrophobicContact CZ3-CB 4.4Å; W173-P198 HydrophobicContact CZ3-CG 4.35Å; P198-S200 PolarHBondContact O-N 3.36Å
199E57.7Low49.7Very low180 Ų180107.4 Ų107.484%0.84162%0.622SS**PPolyproline II helixtrans-66.6129.7177.6-70.2-175.4173.800111.3V201E199-V201 PolarHBondContact O-N 3.11Å
200S47.2Very low49.2Very low113 Ų113108.1 Ų108.179%0.7962%0.617SS**  trans-64.896.1179.8-41.10000111P198 S202P198-S200 PolarHBondContact O-N 3.36Å; S200-S202 PolarHBondContact O-N 3.44Å
201V40.2Very low48.4Very low126 Ų126111.6 Ų111.676%0.76463%0.632SS**  trans-71.3104.9174.9-170.80000109.2E199 N203E199-V201 PolarHBondContact O-N 3.11Å; V201-N203 PolarHBondContact O-N 2.92Å
202S32.7Very low48Very low108 Ų108110 Ų11076%0.75563%0.632SS**  trans-69.711917547.80000111.7S200S200-S202 PolarHBondContact O-N 3.44Å
203N28.7Very low47.8Very low172 Ų172111.3 Ų111.392%0.9264%0.642SS**SBendtrans32.797.4158-75.7-9.3000118.3V201V201-N203 PolarHBondContact O-N 2.92Å
204G29.5Very low46.7Very low63 Ų63109.6 Ų109.665%0.64963%0.631SS**SBendtrans170106156.900000113.8
205N28.7Very low45.8Very low145 Ų145111.6 Ų111.678%0.77564%0.643SS**  trans53.4103.5169.3-78.5-3.2000118.2D207N205-D207 VanDerWaalsContact C-N 3.35Å; N205-D207 PolarHBondContact O-N 2.83Å
206V37Very low44.9Very low130 Ų130110.8 Ų110.879%0.78864%0.641SS**THydrogen-bonded Turntrans-75.2-13.2-176.7178.80000114.1
207D35.8Very low44.2Very low161 Ų161110 Ų11086%0.86163%0.631SS**THydrogen-bonded Turntrans-96.8-0-170.6-64.6-34.1000115.9N205N205-D207 VanDerWaalsContact C-N 3.35Å; N205-D207 PolarHBondContact O-N 2.83Å
208A35.8Very low43.3Very low73 Ų73110.1 Ų110.160%0.60363%0.63SS**SBendtrans-111.9-4.9-177.300000115
209I36.9Very low42.7Very low96 Ų96116.5 Ų116.549%0.49265%0.651SS.*Hα-helixtrans-85.4-12.7-171.1-63.4178.6000112.9S213I209-S213 WeakPolarHBondContact O-CB 3.37Å; I209-S213 PolarHBondContact O-OG 3.15Å
210T47.9Very low42.8Very low98 Ų98115.5 Ų115.560%0.60164%0.639SS**Hα-helixtrans-84.4-34.9-169.4-29.90000114.7V214T210-V214 VanDerWaalsContact O-CB 3.27Å; T210-V214 WeakPolarHBondContact O-CB 3.49Å; T210-V214 WeakPolarHBondContact O-CG2 3.25Å
211E39.7Very low42.7Very low160 Ų160116.6 Ų116.675%0.74863%0.626SS**Hα-helixtrans-86-45.5-174.2-74.6-173163.100113.5V214 I215E211-V214 PolarHBondContact O-N 2.79Å; E211-I215 WeakPolarHBondContact O-CB 3.46Å; E211-I215 WeakPolarHBondContact O-CD1 3.46Å; E211-I215 WeakPolarHBondContact O-CG1 3.42Å; E211-I215 PolarHBondContact O-N 3.1Å
212Q43.7Very low43Very low157 Ų157118.6 Ų118.673%0.73462%0.62SS**Hα-helixtrans-69.9-36.6-178.6-84.4-175.4-24.300112.7I215 E216Q212-I215 PolarHBondContact O-N 2.82Å; Q212-E216 WeakPolarHBondContact O-CB 3.44Å; Q212-E216 PolarHBondContact O-N 3.08Å
213S50.1Low43.7Very low55 Ų55117 Ų11739%0.38560%0.603SS.*Hα-helixtrans-67.6-38.7176.267.10000111.8I209 E217I209-S213 WeakPolarHBondContact O-CB 3.37Å; I209-S213 PolarHBondContact O-OG 3.15Å; S213-E217 WeakPolarHBondContact O-CB 3.37Å; S213-E217 PolarHBondContact O-N 3.18Å
214V45.6Very low44.3Very low59 Ų59114 Ų11436%0.35859%0.587SS.*Hα-helixtrans-66.4-43.3175.5170.80000110.7L190 T210 E211 T218L190-V214 HydrophobicContact CD2-CG2 4.09Å; T210-V214 VanDerWaalsContact O-CB 3.27Å; T210-V214 WeakPolarHBondContact O-CB 3.49Å; T210-V214 WeakPolarHBondContact O-CG2 3.25Å; E211-V214 PolarHBondContact O-N 2.79Å; V214-T218 VanDerWaalsContact O-CB 3.28Å; V214-T218 WeakPolarHBondContact O-CB 3.23Å; V214-T218 PolarHBondContact O-N 3.04Å; V214-T218 PolarHBondContact O-OG1 3.5Å
215I48.4Very low44.8Very low104 Ų104119.6 Ų119.653%0.53359%0.59SS.*Hα-helixtrans-64.7-47.1178-68.4163.9000110.8E211 Q212 E217 T218 R219E211-I215 WeakPolarHBondContact O-CB 3.46Å; E211-I215 WeakPolarHBondContact O-CD1 3.46Å; E211-I215 WeakPolarHBondContact O-CG1 3.42Å; E211-I215 PolarHBondContact O-N 3.1Å; Q212-I215 PolarHBondContact O-N 2.82Å; I215-E217 PolarHBondContact O-N 3.34Å; I215-T218 PolarHBondContact O-N 3.17Å; I215-R219 WeakPolarHBondContact O-CB 3.32Å; I215-R219 PolarHBondContact O-N 2.97Å
216E56.5Low45.1Very low119 Ų119117.4 Ų117.456%0.55658%0.575SS**Hα-helixtrans-64.3-40.4-179.6-160.269.2-162.600111.4Q212 R219 R220Q212-E216 WeakPolarHBondContact O-CB 3.44Å; Q212-E216 PolarHBondContact O-N 3.08Å; E216-R219 WeakPolarHBondContact O-CB 3.15Å; E216-R219 PolarHBondContact O-N 3.03Å; E216-R220 WeakPolarHBondContact O-CB 3.43Å; E216-R220 PolarHBondContact O-N 3.25Å
217E51.3Low44.9Very low83 Ų83116.1 Ų116.139%0.38856%0.56SS.*Hα-helixtrans-72-35.5178-17159.1-156.500112.1S213 I215 R219 R220 R221S213-E217 WeakPolarHBondContact O-CB 3.37Å; S213-E217 PolarHBondContact O-N 3.18Å; I215-E217 PolarHBondContact O-N 3.34Å; E217-R219 VanDerWaalsContact C-N 3.33Å; E217-R220 PolarHBondContact O-N 3.42Å; E217-R221 WeakPolarHBondContact O-CB 3.23Å; E217-R221 WeakPolarHBondContact O-CG 3.48Å; E217-R221 PolarHBondContact O-N 3.16Å; E217-R221 IonicContact OE1-NE 2.92Å
218T51.5Low44.7Very low85 Ų85118.3 Ų118.352%0.52156%0.556SS.*Hα-helixtrans-67.6-36.6173.4-48.80000110.9V214 I215 R221 R222V214-T218 VanDerWaalsContact O-CB 3.28Å; V214-T218 WeakPolarHBondContact O-CB 3.23Å; V214-T218 PolarHBondContact O-N 3.04Å; V214-T218 PolarHBondContact O-OG1 3.5Å; I215-T218 PolarHBondContact O-N 3.17Å; T218-R221 PolarHBondContact O-N 3.23Å; T218-R222 PolarHBondContact O-N 2.94Å
219R52.6Low44.6Very low160 Ų160119.9 Ų119.960%0.60456%0.562SS**Hα-helixtrans-65.3-48173.3-133.8177.5177.7-176.7-2.4111.1I215 E216 E217 R221 R222 D223I215-R219 WeakPolarHBondContact O-CB 3.32Å; I215-R219 PolarHBondContact O-N 2.97Å; E216-R219 WeakPolarHBondContact O-CB 3.15Å; E216-R219 PolarHBondContact O-N 3.03Å; E217-R219 VanDerWaalsContact C-N 3.33Å; R219-R221 VanDerWaalsContact C-N 3.26Å; R219-R221 PolarHBondContact O-N 3.14Å; R219-R222 WeakPolarHBondContact O-CB 3.25Å; R219-R222 PolarHBondContact O-N 3.46Å; R219-R222 VanDerWaalsContact O-N 3.12Å; R219-D223 VanDerWaalsContact O-CG 3.3Å; R219-D223 PolarHBondContact O-N 3.41Å
220R58.5Low44.2Very low159 Ų159122 Ų12260%0.657%0.57SS**Hα-helixtrans-56.5-37.8172.8-107.1-177.6168.6177.2-2.2112.8E216 E217 N224E216-R220 WeakPolarHBondContact O-CB 3.43Å; E216-R220 PolarHBondContact O-N 3.25Å; E217-R220 PolarHBondContact O-N 3.42Å; R220-N224 WeakPolarHBondContact O-CB 3.46Å; R220-N224 PolarHBondContact O-N 3.32Å
221R44.9Very low43.2Very low136 Ų136123.6 Ų123.651%0.51358%0.579SS.*Hα-helixtrans-72.6-37176-77.4-178.8-179-176.9-0.3113.2E217 T218 R219 D223 N224 Y225E217-R221 WeakPolarHBondContact O-CB 3.23Å; E217-R221 WeakPolarHBondContact O-CG 3.48Å; E217-R221 PolarHBondContact O-N 3.16Å; E217-R221 IonicContact OE1-NE 2.92Å; T218-R221 PolarHBondContact O-N 3.23Å; R219-R221 VanDerWaalsContact C-N 3.26Å; R219-R221 PolarHBondContact O-N 3.14Å; R221-D223 VanDerWaalsContact C-N 3.34Å; R221-N224 PolarHBondContact O-N 3.35Å; R221-Y225 WeakPolarHBondContact O-CB 3.47Å; R221-Y225 PolarHBondContact O-N 2.96Å
222R47.4Very low42.7Very low168 Ų168121.2 Ų121.263%0.63458%0.576SS**Hα-helixtrans-62.7-47.2172.1-167.7179.3-161.3143.37.3109.9T218 R219 Y225 E226T218-R222 PolarHBondContact O-N 2.94Å; R219-R222 WeakPolarHBondContact O-CB 3.25Å; R219-R222 PolarHBondContact O-N 3.46Å; R219-R222 VanDerWaalsContact O-N 3.12Å; R222-Y225 PolarHBondContact O-N 3.48Å; R222-E226 IonicContact NE-OE1 3.23Å; R222-E226 PolarHBondContact NE-OE1 3.26Å; R222-E226 VanDerWaalsContact O-CB 3.31Å; R222-E226 WeakPolarHBondContact O-CB 3.4Å; R222-E226 VanDerWaalsContact O-CG 3.31Å; R222-E226 WeakPolarHBondContact O-CG 3.2Å; R222-E226 PolarHBondContact O-N 3.12Å
223D46.4Very low42.2Very low75 Ų75121.1 Ų121.140%0.40158%0.58SS.*Hα-helixtrans-61.6-48.8176.3-64.8-18.5000110.1R219 R221 Y225 E226 H227R219-D223 VanDerWaalsContact O-CG 3.3Å; R219-D223 PolarHBondContact O-N 3.41Å; R221-D223 VanDerWaalsContact C-N 3.34Å; D223-Y225 PolarHBondContact O-N 3.4Å; D223-E226 PolarHBondContact O-N 2.8Å; D223-H227 VanDerWaalsContact O-CB 3.28Å; D223-H227 WeakPolarHBondContact O-CB 3.36Å; D223-H227 VanDerWaalsContact O-CG 3.3Å; D223-H227 PolarHBondContact O-N 3.26Å; D223-H227 PolarHBondContact O-ND1 3.44Å
224N42.3Very low41.2Very low108 Ų108126 Ų12658%0.57860%0.598SS**Hα-helixtrans-66.1-31.8178.7-77.7-7.2000114.1R220 R221 R228R220-N224 WeakPolarHBondContact O-CB 3.46Å; R220-N224 PolarHBondContact O-N 3.32Å; R221-N224 PolarHBondContact O-N 3.35Å; N224-R228 WeakPolarHBondContact O-CB 3.33Å; N224-R228 PolarHBondContact O-N 3.11Å
225Y39.4Very low41.3Very low181 Ų181128.8 Ų128.871%0.7162%0.617SS**Hα-helixtrans-74.9-41.7175.9-176.3-98.2000111R221 R222 D223 H227 R228 S229R221-Y225 WeakPolarHBondContact O-CB 3.47Å; R221-Y225 PolarHBondContact O-N 2.96Å; R222-Y225 PolarHBondContact O-N 3.48Å; D223-Y225 PolarHBondContact O-N 3.4Å; Y225-H227 VanDerWaalsContact C-N 3.31Å; Y225-H227 PolarHBondContact O-N 3.04Å; Y225-R228 PolarHBondContact O-N 3.23Å; Y225-S229 PolarHBondContact O-N 3.17Å; Y225-S229 VanDerWaalsContact O-N 3.15Å
226E34.8Very low40.7Very low99 Ų99128.8 Ų128.846%0.46363%0.626SS.*Hα-helixtrans-66.3-33.1173.2-70.6-177.9-170.100111.5R222 D223R222-E226 IonicContact NE-OE1 3.23Å; R222-E226 PolarHBondContact NE-OE1 3.26Å; R222-E226 VanDerWaalsContact O-CB 3.31Å; R222-E226 WeakPolarHBondContact O-CB 3.4Å; R222-E226 VanDerWaalsContact O-CG 3.31Å; R222-E226 WeakPolarHBondContact O-CG 3.2Å; R222-E226 PolarHBondContact O-N 3.12Å; D223-E226 PolarHBondContact O-N 2.8Å
227H33.8Very low39.6Very low102 Ų102129.9 Ų129.947%0.47264%0.636SS.*Hα-helixtrans-79.2-29.2173.1-72.967000112.8D223 Y225 S229 Q230D223-H227 VanDerWaalsContact O-CB 3.28Å; D223-H227 WeakPolarHBondContact O-CB 3.36Å; D223-H227 VanDerWaalsContact O-CG 3.3Å; D223-H227 PolarHBondContact O-N 3.26Å; D223-H227 PolarHBondContact O-ND1 3.44Å; Y225-H227 VanDerWaalsContact C-N 3.31Å; Y225-H227 PolarHBondContact O-N 3.04Å; H227-S229 VanDerWaalsContact C-N 3.27Å; H227-S229 PolarHBondContact O-N 2.83Å; H227-Q230 CarbonylContact O-C 3.55Å; H227-Q230 WeakPolarHBondContact O-CA 3.14Å; H227-Q230 PolarHBondContact O-N 3.26Å
228R31.7Very low38.8Very low208 Ų208129.6 Ų129.679%0.78564%0.64SS**Hα-helixtrans-71-25.2174.1-176.7177.6-96.7-160.1-5.2112N224 Y225N224-R228 WeakPolarHBondContact O-CB 3.33Å; N224-R228 PolarHBondContact O-N 3.11Å; Y225-R228 PolarHBondContact O-N 3.23Å
229S32.1Very low38.4Very low105 Ų105129.5 Ų129.573%0.73464%0.639SS**THydrogen-bonded Turntrans-76.7-8167.1-170.90000113.3Y225 H227Y225-S229 PolarHBondContact O-N 3.17Å; Y225-S229 VanDerWaalsContact O-N 3.15Å; H227-S229 VanDerWaalsContact C-N 3.27Å; H227-S229 PolarHBondContact O-N 2.83Å
230Q28.6Very low37.9Very low142 Ų142127.7 Ų127.766%0.66464%0.64SS**SBendtrans-126.571.1175.9-66.1-175.923.800108.8H227 T232H227-Q230 CarbonylContact O-C 3.55Å; H227-Q230 WeakPolarHBondContact O-CA 3.14Å; H227-Q230 PolarHBondContact O-N 3.26Å; Q230-T232 PolarHBondContact O-N 2.83Å
231V27.5Very low36.9Very low130 Ų130124 Ų12479%0.78864%0.635SS**  trans-68.779.6166.2-177.60000108.4
232T30.2Very low36.8Very low110 Ų110119.9 Ų119.968%0.67563%0.627SS**SBendtrans-163.1124.8146.247.40000107.5Q230Q230-T232 PolarHBondContact O-N 2.83Å
233D32.6Very low37Very low155 Ų155117 Ų11783%0.82962%0.624SS**  trans82.178.3163.7-54.5-23.1000118.4
234E28.9Very low37Very low159 Ų159119.5 Ų119.574%0.74363%0.633SS**  trans-145.2138.6139.9-95.6-92.7135.500109.6S236E234-S236 PolarHBondContact O-N 2.95Å
235P47.2Very low37Very low117 Ų117119.5 Ų119.576%0.7663%0.633SS**  trans-96.697.3-155.734.4-26.5000111.9
236S35.5Very low37.6Very low103 Ų103114.2 Ų114.272%0.7262%0.619SS**  trans-102.8114.2165.336.90000109.6E234 T238E234-S236 PolarHBondContact O-N 2.95Å; S236-T238 VanDerWaalsContact C-N 3.34Å; S236-T238 PolarHBondContact O-N 2.92Å; S236-T238 PolarHBondContact O-OG1 3.24Å
237D33.4Very low38.8Very low143 Ų143112.2 Ų112.277%0.76562%0.62SS**  trans3.572.5169.1-106.4-37.2000116T239D237-T239 PolarHBondContact O-N 2.93Å; D237-T239 VanDerWaalsContact O-N 3.07Å
238T36.4Very low39.3Very low77 Ų77111.8 Ų111.847%0.47262%0.62SS.*THydrogen-bonded Turntrans-76.47.6-177.1-19.40000111.3S236 I240 V241 S242S236-T238 VanDerWaalsContact C-N 3.34Å; S236-T238 PolarHBondContact O-N 2.92Å; S236-T238 PolarHBondContact O-OG1 3.24Å; T238-I240 VanDerWaalsContact C-N 3.27Å; T238-I240 PolarHBondContact O-N 3.19Å; T238-V241 HydrophobicContact CG2-CB 4.36Å; T238-V241 PolarHBondContact O-N 3.25Å; T238-S242 WeakPolarHBondContact O-CA 3.26Å; T238-S242 WeakPolarHBondContact O-CB 3.44Å; T238-S242 PolarHBondContact O-N 3.24Å; T238-S242 PolarHBondContact O-OG 2.93Å
239T41.5Very low40.1Very low83 Ų83106.2 Ų106.251%0.50961%0.606SS.*Hα-helixtrans-60-34.9-174.445.90000112.7D237 N243D237-T239 PolarHBondContact O-N 2.93Å; D237-T239 VanDerWaalsContact O-N 3.07Å; T239-N243 WeakPolarHBondContact O-CB 3.02Å; T239-N243 PolarHBondContact O-N 2.8Å; T239-N243 VanDerWaalsContact O-N 3.11Å; T239-N243 PolarHBondContact O-ND2 2.83Å; T239-N243 PolarHBondContact O-OD1 3Å
240I42.2Very low41Very low122 Ų122105.9 Ų105.963%0.62660%0.596SS**Hα-helixtrans-76.9-47.6178.9-57.1178.2000111.2T238 N243 E244T238-I240 VanDerWaalsContact C-N 3.27Å; T238-I240 PolarHBondContact O-N 3.19Å; I240-N243 PolarHBondContact O-N 3.12Å; I240-E244 PolarHBondContact O-N 3.31Å
241V38.4Very low42Very low81 Ų81101.7 Ų101.749%0.49159%0.585SS.*Hα-helixtrans-71.2-36.3-177.8-167.20000111.2T238 N243 E244 L245T238-V241 HydrophobicContact CG2-CB 4.36Å; T238-V241 PolarHBondContact O-N 3.25Å; V241-N243 VanDerWaalsContact C-N 3.35Å; V241-E244 PolarHBondContact O-N 2.78Å; V241-L245 HydrophobicContact CG1-CD1 3.93Å; V241-L245 VanDerWaalsContact O-CB 3.3Å; V241-L245 WeakPolarHBondContact O-CB 3.14Å; V241-L245 WeakPolarHBondContact O-CG 3.28Å; V241-L245 PolarHBondContact O-N 2.9Å
242S43Very low42.5Very low50 Ų50101 Ų10135%0.3558%0.575SS.*Hα-helixtrans-65.9-35.3171.5-63.70000111.6T238 T246T238-S242 WeakPolarHBondContact O-CA 3.26Å; T238-S242 WeakPolarHBondContact O-CB 3.44Å; T238-S242 PolarHBondContact O-N 3.24Å; T238-S242 PolarHBondContact O-OG 2.93Å; S242-T246 VanDerWaalsContact O-CB 3.27Å; S242-T246 WeakPolarHBondContact O-CB 3.17Å; S242-T246 WeakPolarHBondContact O-CG2 3.25Å; S242-T246 PolarHBondContact O-N 3.15Å; S242-T246 PolarHBondContact O-OG1 2.73Å
243N51Low43Very low108 Ų108102.3 Ų102.358%0.57857%0.568SS**Hα-helixtrans-68.8-37.6175.3-74.6-10.8000111.8T239 I240 V241 T246 A247T239-N243 WeakPolarHBondContact O-CB 3.02Å; T239-N243 PolarHBondContact O-N 2.8Å; T239-N243 VanDerWaalsContact O-N 3.11Å; T239-N243 PolarHBondContact O-ND2 2.83Å; T239-N243 PolarHBondContact O-OD1 3Å; I240-N243 PolarHBondContact O-N 3.12Å; V241-N243 VanDerWaalsContact C-N 3.35Å; N243-T246 VanDerWaalsContact CA-OG1 3.3Å; N243-T246 WeakPolarHBondContact CA-OG1 3.1Å; N243-T246 PolarHBondContact O-OG1 2.95Å; N243-A247 WeakPolarHBondContact O-CB 3.38Å; N243-A247 PolarHBondContact O-N 2.95Å
244E46.8Very low43.4Very low127 Ų12797.4 Ų97.459%0.59355%0.549SS*.Hα-helixtrans-71.9-40.9174.3-75.1-177.9157.600112I240 V241 A247 I248I240-E244 PolarHBondContact O-N 3.31Å; V241-E244 PolarHBondContact O-N 2.78Å; E244-A247 PolarHBondContact O-N 3.1Å; E244-I248 WeakPolarHBondContact O-CB 3.49Å; E244-I248 WeakPolarHBondContact O-CD1 3.4Å; E244-I248 WeakPolarHBondContact O-CG1 3.36Å; E244-I248 PolarHBondContact O-N 3.19Å
245L41.2Very low43.8Very low107 Ų10796.4 Ų96.456%0.5655%0.549SS*.Hα-helixtrans-67.2-38.4174.7-81.3160.4000112.4V241 I248 D249V241-L245 HydrophobicContact CG1-CD1 3.93Å; V241-L245 VanDerWaalsContact O-CB 3.3Å; V241-L245 WeakPolarHBondContact O-CB 3.14Å; V241-L245 WeakPolarHBondContact O-CG 3.28Å; V241-L245 PolarHBondContact O-N 2.9Å; L245-I248 PolarHBondContact O-N 2.94Å; L245-D249 VanDerWaalsContact O-CB 3.26Å; L245-D249 WeakPolarHBondContact O-CB 3.18Å; L245-D249 PolarHBondContact O-N 2.91Å
246T53.7Low43.2Very low70 Ų7099.2 Ų99.243%0.42955%0.549SS..Hα-helixtrans-71-34.6172.544.80000111.5S242 N243 I248 D249 D250S242-T246 VanDerWaalsContact O-CB 3.27Å; S242-T246 WeakPolarHBondContact O-CB 3.17Å; S242-T246 WeakPolarHBondContact O-CG2 3.25Å; S242-T246 PolarHBondContact O-N 3.15Å; S242-T246 PolarHBondContact O-OG1 2.73Å; N243-T246 VanDerWaalsContact CA-OG1 3.3Å; N243-T246 WeakPolarHBondContact CA-OG1 3.1Å; N243-T246 PolarHBondContact O-OG1 2.95Å; T246-I248 VanDerWaalsContact C-N 3.33Å; T246-I248 PolarHBondContact O-N 2.93Å; T246-D249 PolarHBondContact O-N 3.43Å; T246-D250 WeakPolarHBondContact O-CA 3.41Å; T246-D250 WeakPolarHBondContact O-CB 3.27Å; T246-D250 PolarHBondContact O-N 3.42Å
247A58.3Low43.2Very low58 Ų5899.9 Ų99.948%0.47954%0.541SS..Hα-helixtrans-66-37.1172.200000112.1N243 E244 A251N243-A247 WeakPolarHBondContact O-CB 3.38Å; N243-A247 PolarHBondContact O-N 2.95Å; E244-A247 PolarHBondContact O-N 3.1Å; A247-A251 WeakPolarHBondContact O-CB 3.3Å; A247-A251 PolarHBondContact O-N 2.88Å
248I45.6Very low43.1Very low93 Ų93104.6 Ų104.648%0.47755%0.548SS..Hα-helixtrans-70-43.8174.6-68.9164.7000110.5E244 L245 T246 A251 M252E244-I248 WeakPolarHBondContact O-CB 3.49Å; E244-I248 WeakPolarHBondContact O-CD1 3.4Å; E244-I248 WeakPolarHBondContact O-CG1 3.36Å; E244-I248 PolarHBondContact O-N 3.19Å; L245-I248 PolarHBondContact O-N 2.94Å; T246-I248 VanDerWaalsContact C-N 3.33Å; T246-I248 PolarHBondContact O-N 2.93Å; I248-A251 PolarHBondContact O-N 3.19Å; I248-M252 HydrophobicContact CG2-CE 3.58Å; I248-M252 VanDerWaalsContact O-CG 3.31Å; I248-M252 WeakPolarHBondContact O-CG 3.2Å; I248-M252 PolarHBondContact O-N 3.25Å
249D48.6Very low42.7Very low91 Ų91104.1 Ų104.149%0.48756%0.558SS.*Hα-helixtrans-65.7-44.8176.6-165.862.8000111.1L245 T246 A251 M252 R253L245-D249 VanDerWaalsContact O-CB 3.26Å; L245-D249 WeakPolarHBondContact O-CB 3.18Å; L245-D249 PolarHBondContact O-N 2.91Å; T246-D249 PolarHBondContact O-N 3.43Å; D249-A251 VanDerWaalsContact C-N 3.3Å; D249-A251 PolarHBondContact O-N 3.18Å; D249-M252 CarbonylContact O-C 3.56Å; D249-M252 PolarHBondContact O-N 3Å; D249-M252 VanDerWaalsContact O-N 3.17Å; D249-R253 WeakPolarHBondContact O-CB 3.28Å; D249-R253 PolarHBondContact O-N 3.39Å
250D51.4Low42.1Very low98 Ų98103.4 Ų103.452%0.52457%0.567SS.*Hα-helixtrans-62.1-36173.6-77.7-22.6000111.4T246 R253 A254T246-D250 WeakPolarHBondContact O-CA 3.41Å; T246-D250 WeakPolarHBondContact O-CB 3.27Å; T246-D250 PolarHBondContact O-N 3.42Å; D250-R253 PolarHBondContact O-N 2.97Å; D250-A254 WeakPolarHBondContact O-CB 3.47Å; D250-A254 PolarHBondContact O-N 3.34Å
251A49.2Very low41.3Very low53 Ų53101.1 Ų101.144%0.43857%0.574SS.*Hα-helixtrans-69.8-40.6173.700000112A247 I248 D249 R253 N255A247-A251 WeakPolarHBondContact O-CB 3.3Å; A247-A251 PolarHBondContact O-N 2.88Å; I248-A251 PolarHBondContact O-N 3.19Å; D249-A251 VanDerWaalsContact C-N 3.3Å; D249-A251 PolarHBondContact O-N 3.18Å; A251-R253 VanDerWaalsContact C-N 3.31Å; A251-N255 PolarHBondContact O-N 2.98Å; A251-N255 VanDerWaalsContact O-N 3.14Å
252M37Very low40.5Very low117 Ų117105.5 Ų105.558%0.57659%0.589SS**Hα-helixtrans-66.9-36.3174.2-69.9-153-140.400111.5I248 D249 N255 F256I248-M252 HydrophobicContact CG2-CE 3.58Å; I248-M252 VanDerWaalsContact O-CG 3.31Å; I248-M252 WeakPolarHBondContact O-CG 3.2Å; I248-M252 PolarHBondContact O-N 3.25Å; D249-M252 CarbonylContact O-C 3.56Å; D249-M252 PolarHBondContact O-N 3Å; D249-M252 VanDerWaalsContact O-N 3.17Å; M252-N255 WeakPolarHBondContact O-CB 3.16Å; M252-N255 PolarHBondContact O-N 3.15Å; M252-F256 PolarHBondContact O-N 3.16Å
253R40.2Very low39.8Very low137 Ų137109.9 Ų109.952%0.51761%0.613SS.*Hα-helixtrans-76.9-38.1-179.6-167.1176.1164.71501.3111.8D249 D250 A251 N255 F256 E257D249-R253 WeakPolarHBondContact O-CB 3.28Å; D249-R253 PolarHBondContact O-N 3.39Å; D250-R253 PolarHBondContact O-N 2.97Å; A251-R253 VanDerWaalsContact C-N 3.31Å; R253-N255 VanDerWaalsContact C-N 3.26Å; R253-N255 PolarHBondContact O-N 3.19Å; R253-F256 CarbonylContact O-C 3.55Å; R253-F256 PolarHBondContact O-N 3.42Å; R253-E257 HydrophobicContact CG-CG 4.23Å; R253-E257 IonicContact CZ-OE1 2.73Å; R253-E257 IonicContact NE-OE1 3.99Å; R253-E257 PolarHBondContact NE-OE1 3.32Å; R253-E257 IonicContact NH2-OE1 3.24Å; R253-E257 PolarHBondContact NH2-OE1 2.99Å; R253-E257 WeakPolarHBondContact O-CB 3.38Å; R253-E257 WeakPolarHBondContact O-CG 3.24Å; R253-E257 PolarHBondContact O-N 3.48Å
254A41.1Very low38.5Very low52 Ų52112.5 Ų112.543%0.4362%0.622SS.*Hα-helixtrans-64.4-30.4170.400000112.4D250 F256 R258D250-A254 WeakPolarHBondContact O-CB 3.47Å; D250-A254 PolarHBondContact O-N 3.34Å; A254-F256 VanDerWaalsContact C-N 3.33Å; A254-R258 PolarHBondContact O-N 3.2Å
255N38.5Very low37.5Very low138 Ų138115.8 Ų115.874%0.73864%0.637SS**Hα-helixtrans-70.1-28.1171.9-81.7-9.9000112.9A251 M252 R253A251-N255 PolarHBondContact O-N 2.98Å; A251-N255 VanDerWaalsContact O-N 3.14Å; M252-N255 WeakPolarHBondContact O-CB 3.16Å; M252-N255 PolarHBondContact O-N 3.15Å; R253-N255 VanDerWaalsContact C-N 3.26Å; R253-N255 PolarHBondContact O-N 3.19Å
256F35.4Very low36.8Very low175 Ų175119.2 Ų119.277%0.76865%0.651SS**Hα-helixtrans-88.3-34.3175-94.8-89000113.2M252 R253 A254 G259M252-F256 PolarHBondContact O-N 3.16Å; R253-F256 CarbonylContact O-C 3.55Å; R253-F256 PolarHBondContact O-N 3.42Å; A254-F256 VanDerWaalsContact C-N 3.33Å; F256-G259 PolarHBondContact O-N 3.48Å
257E35Very low35.8Very low118 Ų118125.4 Ų125.455%0.55168%0.675SS**Hα-helixtrans-83.4-7.8-175.7-71.7-176174.800114R253 G259R253-E257 HydrophobicContact CG-CG 4.23Å; R253-E257 IonicContact CZ-OE1 2.73Å; R253-E257 IonicContact NE-OE1 3.99Å; R253-E257 PolarHBondContact NE-OE1 3.32Å; R253-E257 IonicContact NH2-OE1 3.24Å; R253-E257 PolarHBondContact NH2-OE1 2.99Å; R253-E257 WeakPolarHBondContact O-CB 3.38Å; R253-E257 WeakPolarHBondContact O-CG 3.24Å; R253-E257 PolarHBondContact O-N 3.48Å; E257-G259 PolarHBondContact O-N 2.91Å; E257-G259 VanDerWaalsContact O-N 3.1Å
258R31.1Very low34.5Very low241 Ų241129.1 Ų129.191%0.90969%0.687SS**THydrogen-bonded Turntrans-67.91.8163.5-90.5-170-174.6-121.21.7114A254A254-R258 PolarHBondContact O-N 3.2Å
259G27.7Very low34.3Very low67 Ų67133.9 Ų133.969%0.69171%0.707SS**SBendtrans-137.670.4175.500000113.8F256 E257F256-G259 PolarHBondContact O-N 3.48Å; E257-G259 PolarHBondContact O-N 2.91Å; E257-G259 VanDerWaalsContact O-N 3.1Å
260G28.3Very low34.4Very low68 Ų68135.9 Ų135.970%0.70172%0.717SS**  trans160113.8163.100000113.6
261G25.4Very low34.7Very low75 Ų75142.4 Ų142.477%0.77373%0.734SS**  trans-73.5152.8-172.400000114.9
262H22.6Very low36Very low172 Ų172142 Ų14280%0.79673%0.725SS**  trans-31127.3162.1-106.6-82.1000113.9
263V26.9Very low38.1Very low143 Ų143138.7 Ų138.787%0.86771%0.711SS**  trans-137.3115.3151.1-175.80000107.8
264E24.9Very low40Very low162 Ų162139.2 Ų139.276%0.75773%0.725SS**  trans-70.8153176.2-67.6170.8159.200111.1E266E264-E266 PolarHBondContact O-N 2.85Å
265E26.6Very low41.8Very low196 Ų196138.2 Ų138.292%0.91672%0.719SS**  trans-68115-178-60.317015400111.4
266E26.1Very low44.1Very low179 Ų179133.8 Ų133.884%0.83669%0.692SS**  trans-134.7121.8154.9-76.3-169.1159.100109.9E264 D268E264-E266 PolarHBondContact O-N 2.85Å; E266-D268 PolarHBondContact O-N 3.01Å
267E31.6Very low46.2Very low200 Ų200129.1 Ų129.194%0.93568%0.675SS**  trans-69.688.1176.6-67.5-179.5138.600110.5
268D31.4Very low48.6Very low137 Ų137128.4 Ų128.473%0.73367%0.673SS**  trans-101.4117165.7-93.7-32.4000111E266 L270E266-D268 PolarHBondContact O-N 3.01Å; D268-L270 VanDerWaalsContact C-N 3.26Å; D268-L270 PolarHBondContact O-N 3.28Å
269E41.7Very low50.7Low193 Ų193121.7 Ų121.790%0.90265%0.652SS**  trans-56.582.7170.6-68.9-176.7144.900111.2R271E269-R271 PolarHBondContact O-N 2.98Å; E269-R271 VanDerWaalsContact O-N 3.1Å
270L51.3Low52.8Low133 Ų133123 Ų12370%0.69665%0.647SS**  trans-68.9110.8171.7-73.9166000109.4D268 R302D268-L270 VanDerWaalsContact C-N 3.26Å; D268-L270 PolarHBondContact O-N 3.28Å; L270-R302 PolarHBondContact O-NH1 3.23Å
271R56.9Low54.7Low235 Ų235120.5 Ų120.589%0.88762%0.62SS**PPolyproline II helixtrans-51.5143.6170.7-68.6-178.8176.7150.21.8110.6E269E269-R271 PolarHBondContact O-N 2.98Å; E269-R271 VanDerWaalsContact O-N 3.1Å
272L77.3Confident55.8Low45 Ų45124.1 Ų124.124%0.23663%0.629CS.*PPolyproline II helixtrans-55.8147.8177.2-72.6159.9000110.9W276 M278 F288 P301 R302L272-W276 HydrophobicContact CB-CB 4.23Å; L272-M278 HydrophobicContact CD1-CB 3.6Å; L272-F288 HydrophobicContact CD2-CD1 3.82Å; L272-F288 HydrophobicContact CD2-CE1 3.92Å; L272-P301 HydrophobicContact CD2-CG 4.25Å; L272-R302 HydrophobicContact CD2-CG 4.43Å
273P81.2Confident57.6Low46 Ų46121.1 Ų121.130%0.29962%0.619SS.*PPolyproline II helixtrans-57.5146.7177-19.830.6000111.5G275 W276 P301P273-G275 PolarHBondContact O-N 2.71Å; P273-W276 VanDerWaalsContact O-CB 3.31Å; P273-W276 WeakPolarHBondContact O-CB 3.38Å; P273-W276 PolarHBondContact O-N 2.75Å; P273-P301 HydrophobicContact CG-CB 4.47Å; P273-P301 HydrophobicContact CG-CG 4.49Å
274D78.2Confident59.1Low149 Ų149116.8 Ų116.880%0.79760%0.603SS**THydrogen-bonded Turntrans-51.6128.4-178.9-90.1-1.4000112.6R292D274-R292 PolarHBondContact O-NH1 3.4Å
275G79.9Confident60.7Low31 Ų31116.2 Ų116.232%0.3259%0.594SS.*THydrogen-bonded Turntrans900.5-176.800000114.7P273 H291P273-G275 PolarHBondContact O-N 2.71Å; G275-H291 WeakPolarHBondContact O-CB 3.23Å; G275-H291 PolarHBondContact O-CD2 3.08Å; G275-H291 PolarHBondContact O-N 2.91Å
276W87.2Confident62.9Low44 Ų44109.6 Ų109.617%0.16757%0.568CS.*EExtended strand (participates in β ladder)trans-102.4132.7174.7-70.383.8000112.6L272 P273 F288 I289 D290 T297 P301L272-W276 HydrophobicContact CB-CB 4.23Å; P273-W276 VanDerWaalsContact O-CB 3.31Å; P273-W276 WeakPolarHBondContact O-CB 3.38Å; P273-W276 PolarHBondContact O-N 2.75Å; W276-F288 HydrophobicContact CE3-CB 3.85Å; W276-F288 HydrophobicContact CZ3-CB 3.88Å; W276-I289 CarbonylContact C-O 3.52Å; W276-I289 VanDerWaalsContact CA-O 3.24Å; W276-I289 WeakPolarHBondContact CA-O 3.47Å; W276-D290 HydrophobicContact CD2-CB 3.91Å; W276-D290 HydrophobicContact CE3-CB 3.9Å; W276-D290 HydrophobicContact CH2-CB 3.75Å; W276-D290 HydrophobicContact CZ2-CB 3.73Å; W276-D290 HydrophobicContact CZ3-CB 3.83Å; W276-T297 HydrophobicContact CH2-CG2 3.83Å; W276-T297 HydrophobicContact CZ3-CG2 3.57Å; W276-P301 HydrophobicContact CB-CG 4.37Å; W276-P301 HydrophobicContact CD2-CB 3.73Å; W276-P301 HydrophobicContact CD2-CG 3.58Å; W276-P301 HydrophobicContact CE3-CB 3.95Å; W276-P301 HydrophobicContact CE3-CG 3.61Å; W276-P301 HydrophobicContact CG-CB 4.32Å; W276-P301 HydrophobicContact CG-CG 3.96Å; W276-P301 HydrophobicContact CH2-CB 3.88Å; W276-P301 HydrophobicContact CH2-CG 4.41Å; W276-P301 HydrophobicContact CZ2-CB 3.67Å; W276-P301 HydrophobicContact CZ2-CG 4.41Å; W276-P301 HydrophobicContact CZ3-CB 4.02Å; W276-P301 HydrophobicContact CZ3-CG 4.03Å
277D79.8Confident65.3Low78 Ų78102.7 Ų102.742%0.41754%0.535SS..EExtended strand (participates in β ladder)trans-112.1156.6167.5-96.3-16.9000111.1F288 I289 H291D277-F288 CarbonylContact O-C 3.53Å; D277-F288 WeakPolarHBondContact O-CA 3.24Å; D277-I289 HydrophobicContact CB-CB 4.3Å; D277-I289 PolarHBondContact N-O 3.27Å; D277-I289 PolarHBondContact O-N 3.15Å; D277-H291 WeakPolarHBondContact CB-NE2 3.2Å; D277-H291 VanDerWaalsContact CG-NE2 3.27Å; D277-H291 IonicContact OD2-CD2 3.95Å; D277-H291 IonicContact OD2-CE1 3.47Å; D277-H291 IonicContact OD2-NE2 3.43Å; D277-H291 PolarHBondContact OD2-NE2 2.83Å
278M84.6Confident67.9Low102 Ų10293.8 Ų93.850%0.50249%0.493SS..EExtended strand (participates in β ladder)trans-117.3132.3174176.6-176.868.300109.5L272 T286 F288L272-M278 HydrophobicContact CD1-CB 3.6Å; M278-T286 HydrophobicContact CG-CG2 3.21Å; M278-T286 HydrophobicContact SD-CG2 3.54Å; M278-T286 VanDerWaalsContact SD-CG2 3.54Å; M278-F288 HydrophobicContact CB-CD1 4.07Å; M278-F288 HydrophobicContact CB-CE1 4.17Å; M278-F288 HydrophobicContact CG-CD1 4.19Å; M278-F288 HydrophobicContact CG-CE1 3.92Å; M278-F288 HydrophobicContact SD-CE1 4.02Å
279Q74.6Confident70Confident100 Ų10088.4 Ų88.447%0.46746%0.464SS..EExtended strand (participates in β ladder)trans-133.8158.1174.7-75.9-17014.200111.6T286 F287 I289Q279-T286 CarbonylContact O-C 3.58Å; Q279-T286 VanDerWaalsContact O-CA 3.29Å; Q279-T286 WeakPolarHBondContact O-CA 3.39Å; Q279-F287 HydrophobicContact CB-CD1 4.22Å; Q279-F287 HydrophobicContact CB-CE1 3.53Å; Q279-F287 HydrophobicContact CB-CE2 4.2Å; Q279-F287 HydrophobicContact CB-CZ 3.53Å; Q279-F287 HydrophobicContact CG-CZ 4.43Å; Q279-F287 PolarHBondContact N-O 2.87Å; Q279-F287 WeakPolarHBondContact O-CD1 3.37Å; Q279-F287 PolarHBondContact O-N 3.38Å; Q279-I289 HydrophobicContact CB-CD1 4.34Å; Q279-I289 HydrophobicContact CG-CD1 3.93Å
280V73.2Confident71.9Confident95 Ų9579.8 Ų79.858%0.57642%0.424SS*.EExtended strand (participates in β ladder)trans-106.4119.4175.5-177.50000108.3
281A67.1Low72.9Confident16 Ų1678.2 Ų78.213%0.13241%0.413CS..  trans-67.6159.9174.500000110.6N283 G284 R285 F287 W298A281-N283 VanDerWaalsContact CB-OD1 3.28Å; A281-N283 WeakPolarHBondContact CB-OD1 3.31Å; A281-N283 PolarHBondContact O-N 3.06Å; A281-G284 PolarHBondContact O-N 3.06Å; A281-R285 PolarHBondContact N-O 3Å; A281-F287 HydrophobicContact CB-CD1 4.09Å; A281-F287 HydrophobicContact CB-CE1 4.15Å; A281-W298 HydrophobicContact CB-CH2 3.98Å
282P48.6Very low73.7Confident151 Ų15174.8 Ų74.898%0.98140%0.4SS*.THydrogen-bonded Turntrans-56.2-19.5-178.9-2734.9000115.2G284P282-G284 VanDerWaalsContact C-N 3.27Å
283N60.9Low73.9Confident109 Ų10976.6 Ų76.658%0.58341%0.413SS*.THydrogen-bonded Turntrans-85.48.4174.665.90.4000113.7A281 R285A281-N283 VanDerWaalsContact CB-OD1 3.28Å; A281-N283 WeakPolarHBondContact CB-OD1 3.31Å; A281-N283 PolarHBondContact O-N 3.06Å; N283-R285 VanDerWaalsContact C-N 3.27Å; N283-R285 PolarHBondContact O-N 2.86Å; N283-R285 WeakPolarHBondContact OD1-CB 3.44Å; N283-R285 PolarHBondContact OD1-N 3.19Å
284G58Low73.4Confident52 Ų5283.3 Ų83.354%0.53644%0.437SS..SBendtrans79-1.9-179.200000115.1A281 P282A281-G284 PolarHBondContact O-N 3.06Å; P282-G284 VanDerWaalsContact C-N 3.27Å
285R59.6Low72.7Confident149 Ų14979.4 Ų79.456%0.56242%0.419SS*.  trans-81.8131.4178.5-68.5-176.370.61751.7111A281 N283 W298A281-R285 PolarHBondContact N-O 3Å; N283-R285 VanDerWaalsContact C-N 3.27Å; N283-R285 PolarHBondContact O-N 2.86Å; N283-R285 WeakPolarHBondContact OD1-CB 3.44Å; N283-R285 PolarHBondContact OD1-N 3.19Å; R285-W298 HydrophobicContact CB-CE3 4.18Å; R285-W298 HydrophobicContact CB-CH2 4.15Å; R285-W298 HydrophobicContact CB-CZ3 3.43Å; R285-W298 VanDerWaalsContact CB-CZ3 3.43Å
286T71.3Confident72.5Confident58 Ų5882.5 Ų82.536%0.35643%0.432SS..EExtended strand (participates in β ladder)trans-75133.4172.6-50.30000110.9M278 Q279 F288 W298M278-T286 HydrophobicContact CG-CG2 3.21Å; M278-T286 HydrophobicContact SD-CG2 3.54Å; M278-T286 VanDerWaalsContact SD-CG2 3.54Å; Q279-T286 CarbonylContact O-C 3.58Å; Q279-T286 VanDerWaalsContact O-CA 3.29Å; Q279-T286 WeakPolarHBondContact O-CA 3.39Å; T286-F288 HydrophobicContact CG2-CZ 4.22Å; T286-W298 VanDerWaalsContact O-CE3 3.31Å
287F76.7Confident72Confident33 Ų3382.4 Ų82.415%0.14544%0.436CS..EExtended strand (participates in β ladder)trans-129.6156.2170.369-79.4000110.2Q279 A281 I289 T296 W298Q279-F287 HydrophobicContact CB-CD1 4.22Å; Q279-F287 HydrophobicContact CB-CE1 3.53Å; Q279-F287 HydrophobicContact CB-CE2 4.2Å; Q279-F287 HydrophobicContact CB-CZ 3.53Å; Q279-F287 HydrophobicContact CG-CZ 4.43Å; Q279-F287 PolarHBondContact N-O 2.87Å; Q279-F287 WeakPolarHBondContact O-CD1 3.37Å; Q279-F287 PolarHBondContact O-N 3.38Å; A281-F287 HydrophobicContact CB-CD1 4.09Å; A281-F287 HydrophobicContact CB-CE1 4.15Å; F287-I289 HydrophobicContact CD2-CD1 4.43Å; F287-I289 HydrophobicContact CD2-CG1 3.9Å; F287-I289 HydrophobicContact CE2-CD1 3.63Å; F287-I289 HydrophobicContact CE2-CG1 3.58Å; F287-I289 HydrophobicContact CZ-CD1 4.21Å; F287-T296 HydrophobicContact CD2-CG2 4.12Å; F287-T296 HydrophobicContact CE2-CG2 4.03Å; F287-W298 HydrophobicContact CB-CD2 4.16Å; F287-W298 HydrophobicContact CB-CE3 3.69Å; F287-W298 HydrophobicContact CB-CH2 4.14Å; F287-W298 HydrophobicContact CB-CZ3 3.67Å; F287-W298 HydrophobicContact CD1-CH2 4.43Å; F287-W298 HydrophobicContact CD1-CZ3 4.39Å; F287-W298 HydrophobicContact CG-CZ3 4.44Å
288F86.2Confident71.8Confident13 Ų1384.7 Ų84.76%0.05744%0.439CS..EExtended strand (participates in β ladder)trans-113.2138-175.7-55-88.6000109.9L272 W276 D277 M278 T286 T296 T297 T299 D300 P301L272-F288 HydrophobicContact CD2-CD1 3.82Å; L272-F288 HydrophobicContact CD2-CE1 3.92Å; W276-F288 HydrophobicContact CE3-CB 3.85Å; W276-F288 HydrophobicContact CZ3-CB 3.88Å; D277-F288 CarbonylContact O-C 3.53Å; D277-F288 WeakPolarHBondContact O-CA 3.24Å; M278-F288 HydrophobicContact CB-CD1 4.07Å; M278-F288 HydrophobicContact CB-CE1 4.17Å; M278-F288 HydrophobicContact CG-CD1 4.19Å; M278-F288 HydrophobicContact CG-CE1 3.92Å; M278-F288 HydrophobicContact SD-CE1 4.02Å; T286-F288 HydrophobicContact CG2-CZ 4.22Å; F288-T296 CarbonylContact O-C 3.58Å; F288-T296 VanDerWaalsContact O-CA 3.3Å; F288-T296 WeakPolarHBondContact O-CA 3.43Å; F288-T297 HydrophobicContact CB-CG2 4.13Å; F288-T297 PolarHBondContact N-O 3.43Å; F288-T297 PolarHBondContact O-N 3.23Å; F288-T299 WeakPolarHBondContact CD2-O 3.34Å; F288-D300 HydrophobicContact CD2-CB 4.44Å; F288-D300 HydrophobicContact CE1-CB 4.45Å; F288-D300 VanDerWaalsContact CE2-CA 3.42Å; F288-D300 HydrophobicContact CE2-CB 3.74Å; F288-D300 HydrophobicContact CZ-CB 3.74Å; F288-D300 VanDerWaalsContact CZ-CG 3.47Å; F288-D300 VanDerWaalsContact CZ-OD2 3.27Å; F288-D300 WeakPolarHBondContact CZ-OD2 3.49Å; F288-P301 HydrophobicContact CB-CG 4.44Å; F288-P301 HydrophobicContact CD1-CG 4.42Å; F288-P301 HydrophobicContact CG-CG 4.5Å
289I76.5Confident71.2Confident25 Ų2584 Ų8413%0.12844%0.44CS..EExtended strand (participates in β ladder)trans-117118-173.5-47.3-178.1000107.7W276 D277 Q279 F287 T295 T296W276-I289 CarbonylContact C-O 3.52Å; W276-I289 VanDerWaalsContact CA-O 3.24Å; W276-I289 WeakPolarHBondContact CA-O 3.47Å; D277-I289 HydrophobicContact CB-CB 4.3Å; D277-I289 PolarHBondContact N-O 3.27Å; D277-I289 PolarHBondContact O-N 3.15Å; Q279-I289 HydrophobicContact CB-CD1 4.34Å; Q279-I289 HydrophobicContact CG-CD1 3.93Å; F287-I289 HydrophobicContact CD2-CD1 4.43Å; F287-I289 HydrophobicContact CD2-CG1 3.9Å; F287-I289 HydrophobicContact CE2-CD1 3.63Å; F287-I289 HydrophobicContact CE2-CG1 3.58Å; F287-I289 HydrophobicContact CZ-CD1 4.21Å; I289-T295 WeakPolarHBondContact CA-O 3.43Å; I289-T296 HydrophobicContact CB-CG2 4.45Å; I289-T296 HydrophobicContact CG1-CG2 4.09Å; I289-T296 HydrophobicContact CG2-CG2 4.18Å
290D80.6Confident71.2Confident12 Ų1280.6 Ų80.66%0.06443%0.426CS..EExtended strand (participates in β ladder)trans-91.4105.1170.8-179.78.3000109.3W276 R292 T293 K294 T295W276-D290 HydrophobicContact CD2-CB 3.91Å; W276-D290 HydrophobicContact CE3-CB 3.9Å; W276-D290 HydrophobicContact CH2-CB 3.75Å; W276-D290 HydrophobicContact CZ2-CB 3.73Å; W276-D290 HydrophobicContact CZ3-CB 3.83Å; D290-R292 PolarHBondContact O-N 2.87Å; D290-R292 VanDerWaalsContact OD1-CB 3.3Å; D290-R292 WeakPolarHBondContact OD1-CB 3.37Å; D290-R292 PolarHBondContact OD1-N 2.9Å; D290-R292 IonicContact OD1-NE 3.91Å; D290-R292 PolarHBondContact OD1-NE 3.46Å; D290-R292 IonicContact OD1-NH2 3.37Å; D290-T293 WeakPolarHBondContact CB-OG1 3.32Å; D290-T293 VanDerWaalsContact CG-OG1 3.23Å; D290-T293 PolarHBondContact O-N 2.93Å; D290-T293 WeakPolarHBondContact OD2-CG2 3.49Å; D290-T293 PolarHBondContact OD2-OG1 2.94Å; D290-K294 VanDerWaalsContact O-CA 3.23Å; D290-K294 WeakPolarHBondContact O-CA 3.38Å; D290-K294 PolarHBondContact O-N 2.85Å; D290-T295 PolarHBondContact N-O 3.41Å; D290-T295 PolarHBondContact O-N 3.28Å
291H73.6Confident71.4Confident99 Ų9977.7 Ų77.746%0.45841%0.409SS..THydrogen-bonded Turntrans-66.7-18179.4-70.9-72.6000113.4G275 D277G275-H291 WeakPolarHBondContact O-CB 3.23Å; G275-H291 PolarHBondContact O-CD2 3.08Å; G275-H291 PolarHBondContact O-N 2.91Å; D277-H291 WeakPolarHBondContact CB-NE2 3.2Å; D277-H291 VanDerWaalsContact CG-NE2 3.27Å; D277-H291 IonicContact OD2-CD2 3.95Å; D277-H291 IonicContact OD2-CE1 3.47Å; D277-H291 IonicContact OD2-NE2 3.43Å; D277-H291 PolarHBondContact OD2-NE2 2.83Å
292R73.3Confident71.9Confident164 Ų16481 Ų8162%0.61942%0.418SS*.THydrogen-bonded Turntrans-77.4-41178.7-58.2173.5-65.8-171.33.5111.4D274 D290D274-R292 PolarHBondContact O-NH1 3.4Å; D290-R292 PolarHBondContact O-N 2.87Å; D290-R292 VanDerWaalsContact OD1-CB 3.3Å; D290-R292 WeakPolarHBondContact OD1-CB 3.37Å; D290-R292 PolarHBondContact OD1-N 2.9Å; D290-R292 IonicContact OD1-NE 3.91Å; D290-R292 PolarHBondContact OD1-NE 3.46Å; D290-R292 IonicContact OD1-NH2 3.37Å
293T80.8Confident72.5Confident82 Ų8279.9 Ų79.950%0.50341%0.411SS..THydrogen-bonded Turntrans-97.3-8.817858.70000113.1D290 T295D290-T293 WeakPolarHBondContact CB-OG1 3.32Å; D290-T293 VanDerWaalsContact CG-OG1 3.23Å; D290-T293 PolarHBondContact O-N 2.93Å; D290-T293 WeakPolarHBondContact OD2-CG2 3.49Å; D290-T293 PolarHBondContact OD2-OG1 2.94Å; T293-T295 PolarHBondContact O-N 3.46Å; T293-T295 PolarHBondContact OG1-OG1 3.3Å
294K70.1Confident72.1Confident187 Ų18778.6 Ų78.681%0.81342%0.423SS*.THydrogen-bonded Turntrans53.239.3-171-57.7-166.2177.6-171.90112.1D290D290-K294 VanDerWaalsContact O-CA 3.23Å; D290-K294 WeakPolarHBondContact O-CA 3.38Å; D290-K294 PolarHBondContact O-N 2.85Å
295T65.3Low71.5Confident68 Ų6878 Ų7842%0.41741%0.413SS..EExtended strand (participates in β ladder)trans-111.3155.8178.363.10000110.9I289 D290 T293I289-T295 WeakPolarHBondContact CA-O 3.43Å; D290-T295 PolarHBondContact N-O 3.41Å; D290-T295 PolarHBondContact O-N 3.28Å; T293-T295 PolarHBondContact O-N 3.46Å; T293-T295 PolarHBondContact OG1-OG1 3.3Å
296T75.7Confident70.6Confident96 Ų9674.9 Ų74.959%0.58942%0.419SS*.EExtended strand (participates in β ladder)trans-119.1145.1173.358.10000109.6F287 F288 I289F287-T296 HydrophobicContact CD2-CG2 4.12Å; F287-T296 HydrophobicContact CE2-CG2 4.03Å; F288-T296 CarbonylContact O-C 3.58Å; F288-T296 VanDerWaalsContact O-CA 3.3Å; F288-T296 WeakPolarHBondContact O-CA 3.43Å; I289-T296 HydrophobicContact CB-CG2 4.45Å; I289-T296 HydrophobicContact CG1-CG2 4.09Å; I289-T296 HydrophobicContact CG2-CG2 4.18Å
297T74.8Confident69Low42 Ų4276.7 Ų76.726%0.25843%0.43SS..EExtended strand (participates in β ladder)trans-141.7153.4178.5-179.80000110.7W276 F288 T299W276-T297 HydrophobicContact CH2-CG2 3.83Å; W276-T297 HydrophobicContact CZ3-CG2 3.57Å; F288-T297 HydrophobicContact CB-CG2 4.13Å; F288-T297 PolarHBondContact N-O 3.43Å; F288-T297 PolarHBondContact O-N 3.23Å; T297-T299 VanDerWaalsContact C-N 3.34Å; T297-T299 VanDerWaalsContact CG2-O 3.3Å; T297-T299 WeakPolarHBondContact CG2-O 3.49Å; T297-T299 PolarHBondContact OG1-N 3.02Å; T297-T299 VanDerWaalsContact OG1-N 3.11Å
298W76.1Confident66.9Low126 Ų12686.7 Ų86.748%0.47747%0.467SS..SBendtrans-90.3-4.7172.7-62.4100.8000112.6A281 R285 T286 F287A281-W298 HydrophobicContact CB-CH2 3.98Å; R285-W298 HydrophobicContact CB-CE3 4.18Å; R285-W298 HydrophobicContact CB-CH2 4.15Å; R285-W298 HydrophobicContact CB-CZ3 3.43Å; R285-W298 VanDerWaalsContact CB-CZ3 3.43Å; T286-W298 VanDerWaalsContact O-CE3 3.31Å; F287-W298 HydrophobicContact CB-CD2 4.16Å; F287-W298 HydrophobicContact CB-CE3 3.69Å; F287-W298 HydrophobicContact CB-CH2 4.14Å; F287-W298 HydrophobicContact CB-CZ3 3.67Å; F287-W298 HydrophobicContact CD1-CH2 4.43Å; F287-W298 HydrophobicContact CD1-CZ3 4.39Å; F287-W298 HydrophobicContact CG-CZ3 4.44Å
299T71.7Confident64.4Low86 Ų8691.1 Ų91.153%0.52850%0.495SS..SBendtrans-96.4128.1-179.4-50.20000109.4F288 T297F288-T299 WeakPolarHBondContact CD2-O 3.34Å; T297-T299 VanDerWaalsContact C-N 3.34Å; T297-T299 VanDerWaalsContact CG2-O 3.3Å; T297-T299 WeakPolarHBondContact CG2-O 3.49Å; T297-T299 PolarHBondContact OG1-N 3.02Å; T297-T299 VanDerWaalsContact OG1-N 3.11Å
300D75.2Confident62.1Low30 Ų3094.7 Ų94.716%0.1652%0.52CS..  trans-63125.4177.3-162.6-42.6000110.5F288 R302 A305F288-D300 HydrophobicContact CD2-CB 4.44Å; F288-D300 HydrophobicContact CE1-CB 4.45Å; F288-D300 VanDerWaalsContact CE2-CA 3.42Å; F288-D300 HydrophobicContact CE2-CB 3.74Å; F288-D300 HydrophobicContact CZ-CB 3.74Å; F288-D300 VanDerWaalsContact CZ-CG 3.47Å; F288-D300 VanDerWaalsContact CZ-OD2 3.27Å; F288-D300 WeakPolarHBondContact CZ-OD2 3.49Å; D300-R302 PolarHBondContact O-N 3.24Å; D300-R302 VanDerWaalsContact OD1-CB 3.31Å; D300-R302 WeakPolarHBondContact OD1-CB 3.21Å; D300-R302 WeakPolarHBondContact OD1-CG 3.35Å; D300-R302 IonicContact OD1-CZ 3.77Å; D300-R302 PolarHBondContact OD1-N 3.06Å; D300-R302 IonicContact OD1-NE 3.59Å; D300-R302 PolarHBondContact OD1-NE 2.98Å; D300-R302 IonicContact OD1-NH2 2.74Å; D300-R302 IonicContact OD2-CZ 3.77Å; D300-R302 VanDerWaalsContact OD2-CZ 3.31Å; D300-R302 IonicContact OD2-NE 2.88Å; D300-R302 PolarHBondContact OD2-NE 3.4Å; D300-R302 IonicContact OD2-NH2 3.81Å; D300-R302 PolarHBondContact OD2-NH2 3.48Å; D300-A305 HydrophobicContact CB-CB 4.03Å
301P76.4Confident59.7Low34 Ų34102 Ų10222%0.22156%0.558CS.*  trans-76.1-7.8-178.432.9-39.2000113.6L272 P273 W276 F288L272-P301 HydrophobicContact CD2-CG 4.25Å; P273-P301 HydrophobicContact CG-CB 4.47Å; P273-P301 HydrophobicContact CG-CG 4.49Å; W276-P301 HydrophobicContact CB-CG 4.37Å; W276-P301 HydrophobicContact CD2-CB 3.73Å; W276-P301 HydrophobicContact CD2-CG 3.58Å; W276-P301 HydrophobicContact CE3-CB 3.95Å; W276-P301 HydrophobicContact CE3-CG 3.61Å; W276-P301 HydrophobicContact CG-CB 4.32Å; W276-P301 HydrophobicContact CG-CG 3.96Å; W276-P301 HydrophobicContact CH2-CB 3.88Å; W276-P301 HydrophobicContact CH2-CG 4.41Å; W276-P301 HydrophobicContact CZ2-CB 3.67Å; W276-P301 HydrophobicContact CZ2-CG 4.41Å; W276-P301 HydrophobicContact CZ3-CB 4.02Å; W276-P301 HydrophobicContact CZ3-CG 4.03Å; F288-P301 HydrophobicContact CB-CG 4.44Å; F288-P301 HydrophobicContact CD1-CG 4.42Å; F288-P301 HydrophobicContact CG-CG 4.5Å
302R79.5Confident57.6Low85 Ų85104.5 Ų104.532%0.32157%0.574SS.*SBendtrans-70.6124.9179-68.9173-74-172.40.9110.2L270 L272 D300 G304 A305L270-R302 PolarHBondContact O-NH1 3.23Å; L272-R302 HydrophobicContact CD2-CG 4.43Å; D300-R302 PolarHBondContact O-N 3.24Å; D300-R302 VanDerWaalsContact OD1-CB 3.31Å; D300-R302 WeakPolarHBondContact OD1-CB 3.21Å; D300-R302 WeakPolarHBondContact OD1-CG 3.35Å; D300-R302 IonicContact OD1-CZ 3.77Å; D300-R302 PolarHBondContact OD1-N 3.06Å; D300-R302 IonicContact OD1-NE 3.59Å; D300-R302 PolarHBondContact OD1-NE 2.98Å; D300-R302 IonicContact OD1-NH2 2.74Å; D300-R302 IonicContact OD2-CZ 3.77Å; D300-R302 VanDerWaalsContact OD2-CZ 3.31Å; D300-R302 IonicContact OD2-NE 2.88Å; D300-R302 PolarHBondContact OD2-NE 3.4Å; D300-R302 IonicContact OD2-NH2 3.81Å; D300-R302 PolarHBondContact OD2-NH2 3.48Å; R302-G304 PolarHBondContact O-N 2.88Å; R302-A305 HydrophobicContact CB-CB 3.93Å; R302-A305 WeakPolarHBondContact O-CB 3.48Å; R302-A305 PolarHBondContact O-N 3.46Å; R302-A305 VanDerWaalsContact O-N 3.13Å
303P60Low55.5Low128 Ų128108.1 Ų108.183%0.83159%0.588SS**THydrogen-bonded Turntrans-59.4126.5177-18.529.8000110.2
304G52.4Low53.1Low82 Ų82106.8 Ų106.885%0.84559%0.59SS**THydrogen-bonded Turntrans88.2-9.3-179.800000115.5R302 A306R302-G304 PolarHBondContact O-N 2.88Å; G304-A306 PolarHBondContact O-N 3.32Å
305A45.9Very low51.2Low39 Ų39107.5 Ų107.532%0.32259%0.593SS.*  trans-75.467.4167.200000109.6D300 R302 T307D300-A305 HydrophobicContact CB-CB 4.03Å; R302-A305 HydrophobicContact CB-CB 3.93Å; R302-A305 WeakPolarHBondContact O-CB 3.48Å; R302-A305 PolarHBondContact O-N 3.46Å; R302-A305 VanDerWaalsContact O-N 3.13Å; A305-T307 PolarHBondContact O-N 2.75Å; A305-T307 VanDerWaalsContact O-N 3.1Å
306A40.1Very low50Low83 Ų83110.1 Ų110.169%0.68661%0.609SS**  trans-53.7120.7168.600000107.5G304 R308G304-A306 PolarHBondContact O-N 3.32Å; A306-R308 PolarHBondContact O-N 2.97Å
307T39.1Very low48.5Very low96 Ų96111.9 Ų111.959%0.58962%0.615SS**  trans-20.896.6176.117.90000112.5A305 V309A305-T307 PolarHBondContact O-N 2.75Å; A305-T307 VanDerWaalsContact O-N 3.1Å; T307-V309 PolarHBondContact O-N 2.98Å
308R32.7Very low47.4Very low243 Ų243111.4 Ų111.492%0.91761%0.611SS**  trans-68.976.9156.6-82.4-176.1153.4177.7-4.3106.2A306 P310A306-R308 PolarHBondContact O-N 2.97Å; R308-P310 VanDerWaalsContact O-CD 3.22Å; R308-P310 WeakPolarHBondContact O-CD 3.48Å
309V32.9Very low46.6Very low107 Ų107111 Ų11165%0.64862%0.615SS**  trans-59115.6161-168.30000103.7T307 L311T307-V309 PolarHBondContact O-N 2.98Å; V309-L311 PolarHBondContact O-N 2.93Å; V309-L311 VanDerWaalsContact O-N 3.09Å
310P28.8Very low46.2Very low100 Ų100107.9 Ų107.965%0.64959%0.594SS**  trans-54.1128.3170.7-20.632.4000105.9R308 L312R308-P310 VanDerWaalsContact O-CD 3.22Å; R308-P310 WeakPolarHBondContact O-CD 3.48Å; P310-L312 PolarHBondContact O-N 3.41Å
311L28.6Very low45.9Very low164 Ų164108.3 Ų108.386%0.85961%0.606SS**  trans-61.670.2163.7-90.599.2000107.7V309 R313V309-L311 PolarHBondContact O-N 2.93Å; V309-L311 VanDerWaalsContact O-N 3.09Å; L311-R313 PolarHBondContact O-N 3.49Å
312L30.3Very low45.8Very low153 Ų153111 Ų11180%0.80163%0.631SS**  trans-64.596.3147-76.2168.6000103P310 G314P310-L312 PolarHBondContact O-N 3.41Å; L312-G314 PolarHBondContact O-N 3.3Å
313R28.4Very low45.7Very low240 Ų240109 Ų10991%0.90663%0.626SS**  trans-54.263156.1-78.9176.4159.3-179-4.8109L311L311-R313 PolarHBondContact O-N 3.49Å
314G30.8Very low46.7Very low54 Ų54105.3 Ų105.356%0.55760%0.603SS**  trans-9691.6155.300000104.4L312 T316L312-G314 PolarHBondContact O-N 3.3Å; G314-T316 PolarHBondContact O-N 3.49Å
315K30.8Very low47.9Very low202 Ų202105.7 Ų105.788%0.87860%0.597SS**  trans-49.2103.9154.1-81.3179.3171.2-176.70105D317K315-D317 PolarHBondContact O-N 2.99Å; K315-D317 VanDerWaalsContact O-N 3.09Å
316T39.3Very low49.6Very low122 Ų122105.2 Ų105.275%0.74860%0.597SS**  trans-64.6112.416349.20000104.1G314 D318G314-T316 PolarHBondContact O-N 3.49Å; T316-D318 PolarHBondContact O-N 2.81Å
317D45.2Very low51.8Low134 Ų134102.8 Ų102.872%0.71757%0.57SS**  trans-67.634.7-174.8-154.327.8000112.5K315K315-D317 PolarHBondContact O-N 2.99Å; K315-D317 VanDerWaalsContact O-N 3.09Å
318D51.8Low54Low32 Ų32101.1 Ų101.117%0.17156%0.555CS.*  trans-104.890.7-172.2-101.929.8000109.3T316 I320 G321 R353 K634T316-D318 PolarHBondContact O-N 2.81Å; D318-I320 PolarHBondContact O-N 2.93Å; D318-G321 PolarHBondContact O-N 3.24Å; D318-G321 VanDerWaalsContact O-N 3.13Å; D318-R353 IonicContact OD2-CZ 2.8Å; D318-R353 IonicContact OD2-NH1 2.64Å; D318-R353 PolarHBondContact OD2-NH1 2.91Å; D318-R353 IonicContact OD2-NH2 3.23Å; D318-R353 PolarHBondContact OD2-NH2 3.42Å; D318-K634 IonicContact OD1-NZ 2.76Å; D318-K634 PolarHBondContact OD1-NZ 3.39Å; D318-K634 IonicContact OD2-NZ 2.97Å
319E57.9Low56.4Low118 Ų11892.7 Ų92.755%0.55153%0.526SS*.THydrogen-bonded Turntrans-57.9-9174.6-63.2169.4134.500114.2G321 K707E319-G321 VanDerWaalsContact C-N 3.25Å; E319-G321 PolarHBondContact O-N 3.42Å; E319-K707 IonicContact OE1-NZ 3.33Å; E319-K707 PolarHBondContact OE1-NZ 3.37Å; E319-K707 IonicContact OE2-NZ 3.93Å; E319-K707 PolarHBondContact OE2-NZ 3.45Å
320I64.3Low58.7Low20 Ų2093.6 Ų93.610%0.10352%0.518CS..THydrogen-bonded Turntrans-81-8.6178.5-50.3178.8000111.4D318 K634 L637D318-I320 PolarHBondContact O-N 2.93Å; I320-K634 HydrophobicContact CD1-CB 4.36Å; I320-K634 HydrophobicContact CD1-CD 4.28Å; I320-K634 HydrophobicContact CD1-CG 3.33Å; I320-K634 WeakPolarHBondContact CD1-O 3.4Å; I320-L637 HydrophobicContact CD1-CB 4.42Å
321G68.3Low60.7Low39 Ų3993.5 Ų93.540%0.40252%0.515SS..  trans87.5178.2-173.800000113D318 E319 R353D318-G321 PolarHBondContact O-N 3.24Å; D318-G321 VanDerWaalsContact O-N 3.13Å; E319-G321 VanDerWaalsContact C-N 3.25Å; E319-G321 PolarHBondContact O-N 3.42Å; G321-R353 PolarHBondContact O-NH1 3.18Å
322A75.6Confident62.9Low91 Ų9189.9 Ų89.975%0.75249%0.494SS*.PPolyproline II helixtrans-65.3148.9-173.200000112.7
323L77Confident64.7Low42 Ų4287.6 Ų87.622%0.2250%0.497CS..PPolyproline II helixtrans-62.9149.5168.5-69.7168000110.2W327 Q329 F339 P352L323-W327 HydrophobicContact CB-CB 3.93Å; L323-W327 HydrophobicContact CD1-CB 4.47Å; L323-Q329 HydrophobicContact CD1-CB 3.78Å; L323-F339 HydrophobicContact CD2-CD1 3.87Å; L323-F339 HydrophobicContact CD2-CE1 3.85Å; L323-P352 HydrophobicContact CD2-CG 3.94Å
324P79.7Confident66.6Low51 Ų5180 Ų8033%0.33147%0.474SS..PPolyproline II helixtrans-56.8155.4174.5-2031.3000111.6G326 W327 P352P324-G326 PolarHBondContact O-N 2.86Å; P324-W327 WeakPolarHBondContact O-CB 3.46Å; P324-W327 PolarHBondContact O-N 2.91Å; P324-P352 HydrophobicContact CG-CB 4.23Å; P324-P352 HydrophobicContact CG-CG 4.29Å
325A79.3Confident68Low89 Ų8979.4 Ų79.474%0.73647%0.468SS*.THydrogen-bonded Turntrans-54.5131.5-178.200000112.2N343A325-N343 PolarHBondContact O-ND2 3.27Å
326G80.9Confident69.7Low30 Ų3074.1 Ų74.131%0.30944%0.443SS..THydrogen-bonded Turntrans82.97-17800000115.2P324 H342P324-G326 PolarHBondContact O-N 2.86Å; G326-H342 VanDerWaalsContact O-CB 3.28Å; G326-H342 WeakPolarHBondContact O-CB 3.39Å; G326-H342 PolarHBondContact O-CD2 3.16Å; G326-H342 PolarHBondContact O-N 3.44Å
327W86.1Confident71.4Confident32 Ų3269.4 Ų69.412%0.12141%0.413CS..EExtended strand (participates in β ladder)trans-100.1139.1173.6-70.682.2000112.6L323 P324 F339 I340 D341 Q348 P352L323-W327 HydrophobicContact CB-CB 3.93Å; L323-W327 HydrophobicContact CD1-CB 4.47Å; P324-W327 WeakPolarHBondContact O-CB 3.46Å; P324-W327 PolarHBondContact O-N 2.91Å; W327-F339 HydrophobicContact CE3-CB 3.91Å; W327-F339 HydrophobicContact CZ3-CB 3.93Å; W327-I340 CarbonylContact C-O 3.57Å; W327-I340 VanDerWaalsContact CA-O 3.3Å; W327-I340 WeakPolarHBondContact CA-O 3.43Å; W327-D341 HydrophobicContact CD2-CB 4.11Å; W327-D341 HydrophobicContact CE3-CB 4.02Å; W327-D341 HydrophobicContact CH2-CB 3.66Å; W327-D341 HydrophobicContact CZ2-CB 3.73Å; W327-D341 WeakPolarHBondContact CZ2-OD2 3.35Å; W327-D341 HydrophobicContact CZ3-CB 3.81Å; W327-Q348 HydrophobicContact CH2-CG 4.08Å; W327-Q348 VanDerWaalsContact CH2-NE2 3.34Å; W327-Q348 HydrophobicContact CZ3-CG 3.79Å; W327-P352 HydrophobicContact CB-CG 4.31Å; W327-P352 HydrophobicContact CD2-CB 3.59Å; W327-P352 HydrophobicContact CD2-CG 3.51Å; W327-P352 VanDerWaalsContact CE2-CB 3.49Å; W327-P352 HydrophobicContact CE3-CB 3.79Å; W327-P352 HydrophobicContact CE3-CG 3.55Å; W327-P352 HydrophobicContact CG-CB 4.21Å; W327-P352 HydrophobicContact CG-CG 3.87Å; W327-P352 HydrophobicContact CH2-CB 3.79Å; W327-P352 HydrophobicContact CH2-CG 4.44Å; W327-P352 HydrophobicContact CZ2-CB 3.6Å; W327-P352 HydrophobicContact CZ2-CG 4.43Å; W327-P352 HydrophobicContact CZ3-CB 3.88Å; W327-P352 HydrophobicContact CZ3-CG 4.03Å
328E85Confident73Confident60 Ų6064.7 Ų64.728%0.2839%0.387SS..EExtended strand (participates in β ladder)trans-125.9135.9173.8-179.7-174.7168.900110.2R330 F339 I340 H342E328-R330 HydrophobicContact CG-CG 4.37Å; E328-R330 IonicContact OE1-CZ 3.43Å; E328-R330 VanDerWaalsContact OE1-CZ 3.23Å; E328-R330 IonicContact OE1-NE 3.18Å; E328-R330 PolarHBondContact OE1-NE 2.79Å; E328-R330 IonicContact OE1-NH2 3.08Å; E328-R330 PolarHBondContact OE1-NH2 3.23Å; E328-R330 IonicContact OE2-NE 2.64Å; E328-R330 IonicContact OE2-NH2 3.31Å; E328-F339 CarbonylContact O-C 3.54Å; E328-F339 WeakPolarHBondContact O-CA 3.15Å; E328-I340 HydrophobicContact CB-CB 4.31Å; E328-I340 PolarHBondContact N-O 3.46Å; E328-I340 PolarHBondContact O-N 2.86Å; E328-H342 WeakPolarHBondContact CB-NE2 3.45Å; E328-H342 IonicContact OE2-CE1 2.82Å; E328-H342 PolarHBondContact OE2-CE1 2.88Å; E328-H342 VanDerWaalsContact OE2-CE1 3.26Å; E328-H342 IonicContact OE2-NE2 3.61Å; E328-H342 PolarHBondContact OE2-NE2 2.97Å
329Q83.9Confident74.7Confident67 Ų6763.2 Ų63.231%0.31338%0.379SS..EExtended strand (participates in β ladder)trans-95.2135172.2178.6-179.4-54.600110.4L323 V337 F339L323-Q329 HydrophobicContact CD1-CB 3.78Å; Q329-V337 HydrophobicContact CG-CG1 3.32Å; Q329-F339 HydrophobicContact CB-CD1 4.16Å; Q329-F339 HydrophobicContact CB-CE1 4.14Å; Q329-F339 HydrophobicContact CG-CD1 4.38Å; Q329-F339 HydrophobicContact CG-CE1 4.02Å
330R81.2Confident76Confident126 Ų12658.7 Ų58.748%0.47536%0.358SS..EExtended strand (participates in β ladder)trans-133.5161.9172.3-70.6-160.8-176.1-174.21112.1E328 V337 F338 I340E328-R330 HydrophobicContact CG-CG 4.37Å; E328-R330 IonicContact OE1-CZ 3.43Å; E328-R330 VanDerWaalsContact OE1-CZ 3.23Å; E328-R330 IonicContact OE1-NE 3.18Å; E328-R330 PolarHBondContact OE1-NE 2.79Å; E328-R330 IonicContact OE1-NH2 3.08Å; E328-R330 PolarHBondContact OE1-NH2 3.23Å; E328-R330 IonicContact OE2-NE 2.64Å; E328-R330 IonicContact OE2-NH2 3.31Å; R330-V337 CarbonylContact O-C 3.52Å; R330-V337 WeakPolarHBondContact O-CA 3.26Å; R330-F338 HydrophobicContact CB-CD1 4.05Å; R330-F338 HydrophobicContact CB-CE1 3.46Å; R330-F338 VanDerWaalsContact CB-CE1 3.46Å; R330-F338 HydrophobicContact CB-CE2 4.14Å; R330-F338 HydrophobicContact CB-CZ 3.52Å; R330-F338 HydrophobicContact CG-CZ 4.34Å; R330-F338 PolarHBondContact N-O 3.32Å; R330-F338 WeakPolarHBondContact O-CD1 3.37Å; R330-F338 PolarHBondContact O-N 3.15Å; R330-I340 HydrophobicContact CG-CD1 3.9Å
331V70.9Confident77Confident98 Ų9857.8 Ų57.859%0.59435%0.353SS*.EExtended strand (participates in β ladder)trans-106.3123.4173.5-174.50000108.2R336 V337V331-R336 CarbonylContact C-O 3.55Å; V331-R336 WeakPolarHBondContact CA-O 3.38Å; V331-V337 HydrophobicContact CG2-CG2 4.45Å
332H74.3Confident77.5Confident87 Ų8760.5 Ų60.540%0.40336%0.355SS..  trans-74.2163.3174.5-176.8-96.9000110.5D334 G335 R336 F338 W349H332-D334 WeakPolarHBondContact CB-OD1 3.28Å; H332-D334 IonicContact CE1-OD1 3.45Å; H332-D334 IonicContact CG-OD1 2.71Å; H332-D334 VanDerWaalsContact ND1-CG 3.27Å; H332-D334 IonicContact ND1-OD1 3.3Å; H332-D334 PolarHBondContact ND1-OD1 3.21Å; H332-D334 IonicContact ND1-OD2 2.68Å; H332-D334 PolarHBondContact O-N 2.86Å; H332-G335 WeakPolarHBondContact O-CA 3.38Å; H332-G335 PolarHBondContact O-N 2.81Å; H332-R336 WeakPolarHBondContact CB-O 3.2Å; H332-R336 PolarHBondContact N-O 3.44Å; H332-F338 HydrophobicContact CB-CD1 3.88Å; H332-F338 HydrophobicContact CB-CE1 4.05Å; H332-W349 HydrophobicContact CB-CH2 3.97Å; H332-W349 HydrophobicContact CB-CZ3 4.13Å; H332-W349 AromaticContact CG-CH2 3.89Å
333A67.2Low77.6Confident105 Ų10561.5 Ų61.587%0.86835%0.348SS*.THydrogen-bonded Turntrans-61-21-173.700000114.5G335A333-G335 VanDerWaalsContact C-N 3.28Å
334D69.4Low77.9Confident81 Ų8167.2 Ų67.243%0.43337%0.367SS..THydrogen-bonded Turntrans-87.97.9174.767.4-12.7000113.3H332 R336H332-D334 WeakPolarHBondContact CB-OD1 3.28Å; H332-D334 IonicContact CE1-OD1 3.45Å; H332-D334 IonicContact CG-OD1 2.71Å; H332-D334 VanDerWaalsContact ND1-CG 3.27Å; H332-D334 IonicContact ND1-OD1 3.3Å; H332-D334 PolarHBondContact ND1-OD1 3.21Å; H332-D334 IonicContact ND1-OD2 2.68Å; H332-D334 PolarHBondContact O-N 2.86Å; D334-R336 VanDerWaalsContact C-N 3.31Å; D334-R336 VanDerWaalsContact OD1-CB 3.3Å; D334-R336 WeakPolarHBondContact OD1-CB 3.45Å; D334-R336 WeakPolarHBondContact OD1-CG 3.24Å; D334-R336 PolarHBondContact OD1-N 3.21Å; D334-R336 VanDerWaalsContact OD1-N 3.1Å; D334-R336 WeakPolarHBondContact OD2-CD 3.44Å; D334-R336 WeakPolarHBondContact OD2-CG 3.36Å; D334-R336 IonicContact OD2-CZ 3.56Å; D334-R336 IonicContact OD2-NE 3.56Å; D334-R336 PolarHBondContact OD2-NE 2.95Å; D334-R336 VanDerWaalsContact OD2-NE 3.1Å
335G60.7Low77.7Confident41 Ų4176 Ų7642%0.42339%0.394SS..SBendtrans83.8-1.6-178.100000114.6H332 A333H332-G335 WeakPolarHBondContact O-CA 3.38Å; H332-G335 PolarHBondContact O-N 2.81Å; A333-G335 VanDerWaalsContact C-N 3.28Å
336R65Low77.8Confident92 Ų9278 Ų7835%0.34738%0.382SS..  trans-76.6138.7-178.9-66.6-178-170.1176.64112.1V331 H332 D334 W349V331-R336 CarbonylContact C-O 3.55Å; V331-R336 WeakPolarHBondContact CA-O 3.38Å; H332-R336 WeakPolarHBondContact CB-O 3.2Å; H332-R336 PolarHBondContact N-O 3.44Å; D334-R336 VanDerWaalsContact C-N 3.31Å; D334-R336 VanDerWaalsContact OD1-CB 3.3Å; D334-R336 WeakPolarHBondContact OD1-CB 3.45Å; D334-R336 WeakPolarHBondContact OD1-CG 3.24Å; D334-R336 PolarHBondContact OD1-N 3.21Å; D334-R336 VanDerWaalsContact OD1-N 3.1Å; D334-R336 WeakPolarHBondContact OD2-CD 3.44Å; D334-R336 WeakPolarHBondContact OD2-CG 3.36Å; D334-R336 IonicContact OD2-CZ 3.56Å; D334-R336 IonicContact OD2-NE 3.56Å; D334-R336 PolarHBondContact OD2-NE 2.95Å; D334-R336 VanDerWaalsContact OD2-NE 3.1Å; R336-W349 HydrophobicContact CB-CE3 4.33Å; R336-W349 HydrophobicContact CB-CH2 4.48Å; R336-W349 HydrophobicContact CB-CZ3 3.65Å
337V76.1Confident78Confident22 Ų2280.9 Ų80.913%0.13339%0.393CS..EExtended strand (participates in β ladder)trans-79.8134.5173.4-177.60000109.9Q329 R330 V331 F339Q329-V337 HydrophobicContact CG-CG1 3.32Å; R330-V337 CarbonylContact O-C 3.52Å; R330-V337 WeakPolarHBondContact O-CA 3.26Å; V331-V337 HydrophobicContact CG2-CG2 4.45Å; V337-F339 HydrophobicContact CG1-CE1 4.47Å; V337-F339 HydrophobicContact CG1-CE2 4.2Å; V337-F339 HydrophobicContact CG1-CZ 3.98Å
338F78.6Confident77.8Confident36 Ų3680.2 Ų80.216%0.15839%0.392CS..EExtended strand (participates in β ladder)trans-133.6155.8170.972.2-80.4000110.6R330 H332 I340 T347 W349R330-F338 HydrophobicContact CB-CD1 4.05Å; R330-F338 HydrophobicContact CB-CE1 3.46Å; R330-F338 VanDerWaalsContact CB-CE1 3.46Å; R330-F338 HydrophobicContact CB-CE2 4.14Å; R330-F338 HydrophobicContact CB-CZ 3.52Å; R330-F338 HydrophobicContact CG-CZ 4.34Å; R330-F338 PolarHBondContact N-O 3.32Å; R330-F338 WeakPolarHBondContact O-CD1 3.37Å; R330-F338 PolarHBondContact O-N 3.15Å; H332-F338 HydrophobicContact CB-CD1 3.88Å; H332-F338 HydrophobicContact CB-CE1 4.05Å; F338-I340 HydrophobicContact CD2-CG1 3.99Å; F338-I340 HydrophobicContact CE2-CD1 3.71Å; F338-I340 HydrophobicContact CE2-CG1 3.66Å; F338-I340 HydrophobicContact CZ-CD1 4.31Å; F338-T347 HydrophobicContact CD2-CG2 4.34Å; F338-T347 HydrophobicContact CE2-CG2 4.21Å; F338-W349 HydrophobicContact CB-CD2 4.25Å; F338-W349 HydrophobicContact CB-CE3 3.64Å; F338-W349 HydrophobicContact CB-CH2 4.42Å; F338-W349 HydrophobicContact CB-CZ3 3.74Å; F338-W349 HydrophobicContact CG-CZ3 4.49Å
339F87.5Confident77.6Confident0 Ų083.2 Ų83.20%040%0.401CS..EExtended strand (participates in β ladder)trans-114.7138.1-174.2-57.7-89.3000110.1L323 W327 E328 Q329 V337 T347 Q348 E350 D351 H630L323-F339 HydrophobicContact CD2-CD1 3.87Å; L323-F339 HydrophobicContact CD2-CE1 3.85Å; W327-F339 HydrophobicContact CE3-CB 3.91Å; W327-F339 HydrophobicContact CZ3-CB 3.93Å; E328-F339 CarbonylContact O-C 3.54Å; E328-F339 WeakPolarHBondContact O-CA 3.15Å; Q329-F339 HydrophobicContact CB-CD1 4.16Å; Q329-F339 HydrophobicContact CB-CE1 4.14Å; Q329-F339 HydrophobicContact CG-CD1 4.38Å; Q329-F339 HydrophobicContact CG-CE1 4.02Å; V337-F339 HydrophobicContact CG1-CE1 4.47Å; V337-F339 HydrophobicContact CG1-CE2 4.2Å; V337-F339 HydrophobicContact CG1-CZ 3.98Å; F339-T347 CarbonylContact O-C 3.54Å; F339-T347 VanDerWaalsContact O-CA 3.3Å; F339-T347 WeakPolarHBondContact O-CA 3.17Å; F339-Q348 HydrophobicContact CB-CG 4.35Å; F339-Q348 PolarHBondContact N-O 2.6Å; F339-Q348 PolarHBondContact O-N 3.07Å; F339-E350 VanDerWaalsContact CD2-C 3.48Å; F339-E350 WeakPolarHBondContact CD2-O 3.45Å; F339-D351 HydrophobicContact CD2-CB 4.37Å; F339-D351 HydrophobicContact CE1-CB 4.19Å; F339-D351 HydrophobicContact CE2-CB 3.67Å; F339-D351 HydrophobicContact CZ-CB 3.55Å; F339-D351 WeakPolarHBondContact CZ-OD2 3.36Å; F339-H630 AromaticContact CE2-NE2 3.92Å
340I85.4Confident77.3Confident23 Ų2385.1 Ų85.112%0.11841%0.41CS..EExtended strand (participates in β ladder)trans-115.3114.5-177.2-50.4-178.7000107.5W327 E328 R330 F338 H342 T347W327-I340 CarbonylContact C-O 3.57Å; W327-I340 VanDerWaalsContact CA-O 3.3Å; W327-I340 WeakPolarHBondContact CA-O 3.43Å; E328-I340 HydrophobicContact CB-CB 4.31Å; E328-I340 PolarHBondContact N-O 3.46Å; E328-I340 PolarHBondContact O-N 2.86Å; R330-I340 HydrophobicContact CG-CD1 3.9Å; F338-I340 HydrophobicContact CD2-CG1 3.99Å; F338-I340 HydrophobicContact CE2-CD1 3.71Å; F338-I340 HydrophobicContact CE2-CG1 3.66Å; F338-I340 HydrophobicContact CZ-CD1 4.31Å; I340-H342 PolarHBondContact O-N 2.87Å; I340-T347 HydrophobicContact CB-CG2 4.47Å; I340-T347 HydrophobicContact CG1-CG2 4.01Å; I340-T347 HydrophobicContact CG2-CG2 4.27Å
341D85Confident77.3Confident1 Ų179.3 Ų79.31%0.00539%0.388CS..EExtended strand (participates in β ladder)trans-84.8101.5168.9-174.2-17.7000108.1W327 N343 R344 R345 R346W327-D341 HydrophobicContact CD2-CB 4.11Å; W327-D341 HydrophobicContact CE3-CB 4.02Å; W327-D341 HydrophobicContact CH2-CB 3.66Å; W327-D341 HydrophobicContact CZ2-CB 3.73Å; W327-D341 WeakPolarHBondContact CZ2-OD2 3.35Å; W327-D341 HydrophobicContact CZ3-CB 3.81Å; D341-N343 VanDerWaalsContact C-N 3.27Å; D341-N343 WeakPolarHBondContact OD1-CA 3.42Å; D341-N343 VanDerWaalsContact OD1-CB 3.23Å; D341-N343 WeakPolarHBondContact OD1-CB 3.37Å; D341-N343 PolarHBondContact OD1-N 3.05Å; D341-R344 HydrophobicContact CB-CB 4.43Å; D341-R344 PolarHBondContact OD1-N 2.91Å; D341-R344 WeakPolarHBondContact OD2-CB 3.42Å; D341-R344 WeakPolarHBondContact OD2-CD 3.49Å; D341-R344 VanDerWaalsContact OD2-CG 3.25Å; D341-R344 WeakPolarHBondContact OD2-CG 3.36Å; D341-R344 IonicContact OD2-NH1 3.87Å; D341-R344 PolarHBondContact OD2-NH1 3.47Å; D341-R345 WeakPolarHBondContact O-CA 3.23Å; D341-R345 PolarHBondContact O-N 3.28Å; D341-R346 PolarHBondContact N-O 3.49Å; D341-R346 PolarHBondContact O-N 3.46Å; D341-R346 VanDerWaalsContact O-N 3.11Å
342H78.6Confident77.8Confident96 Ų9674.9 Ų74.944%0.44436%0.361SS..THydrogen-bonded Turntrans-69.6-25.6175.6-69.1-74.9000112.3G326 E328 I340G326-H342 VanDerWaalsContact O-CB 3.28Å; G326-H342 WeakPolarHBondContact O-CB 3.39Å; G326-H342 PolarHBondContact O-CD2 3.16Å; G326-H342 PolarHBondContact O-N 3.44Å; E328-H342 WeakPolarHBondContact CB-NE2 3.45Å; E328-H342 IonicContact OE2-CE1 2.82Å; E328-H342 PolarHBondContact OE2-CE1 2.88Å; E328-H342 VanDerWaalsContact OE2-CE1 3.26Å; E328-H342 IonicContact OE2-NE2 3.61Å; E328-H342 PolarHBondContact OE2-NE2 2.97Å; I340-H342 PolarHBondContact O-N 2.87Å
343N78.7Confident78.1Confident113 Ų11370.9 Ų70.960%0.60434%0.342SS*.THydrogen-bonded Turntrans-70.9-41.2178.7-52.4-48.6000110.9A325 D341A325-N343 PolarHBondContact O-ND2 3.27Å; D341-N343 VanDerWaalsContact C-N 3.27Å; D341-N343 WeakPolarHBondContact OD1-CA 3.42Å; D341-N343 VanDerWaalsContact OD1-CB 3.23Å; D341-N343 WeakPolarHBondContact OD1-CB 3.37Å; D341-N343 PolarHBondContact OD1-N 3.05Å
344R81.5Confident78.2Confident162 Ų16266.9 Ų66.961%0.61131%0.305SS*.THydrogen-bonded Turntrans-101.20.3179.2-59.6-172.4-179.2113.9-9114.2D341 R346D341-R344 HydrophobicContact CB-CB 4.43Å; D341-R344 PolarHBondContact OD1-N 2.91Å; D341-R344 WeakPolarHBondContact OD2-CB 3.42Å; D341-R344 WeakPolarHBondContact OD2-CD 3.49Å; D341-R344 VanDerWaalsContact OD2-CG 3.25Å; D341-R344 WeakPolarHBondContact OD2-CG 3.36Å; D341-R344 IonicContact OD2-NH1 3.87Å; D341-R344 PolarHBondContact OD2-NH1 3.47Å; R344-R346 VanDerWaalsContact C-N 3.26Å; R344-R346 PolarHBondContact O-N 2.76Å
345R77.2Confident78Confident235 Ų23568.4 Ų68.489%0.88731%0.31SS*.THydrogen-bonded Turntrans49.545.2-176.8-59.9-178.5178-179.5-0.9112.7D341D341-R345 WeakPolarHBondContact O-CA 3.23Å; D341-R345 PolarHBondContact O-N 3.28Å
346R81.8Confident78.3Confident132 Ų13269.5 Ų69.550%0.49831%0.306SS..EExtended strand (participates in β ladder)trans-127.1143.9-179.4-172.2175.969.5-172.92.7110D341 R344D341-R346 PolarHBondContact N-O 3.49Å; D341-R346 PolarHBondContact O-N 3.46Å; D341-R346 VanDerWaalsContact O-N 3.11Å; R344-R346 VanDerWaalsContact C-N 3.26Å; R344-R346 PolarHBondContact O-N 2.76Å
347T85.1Confident77.9Confident89 Ų8971.7 Ų71.755%0.54632%0.321SS..EExtended strand (participates in β ladder)trans-101.5147167.861.30000109.9F338 F339 I340F338-T347 HydrophobicContact CD2-CG2 4.34Å; F338-T347 HydrophobicContact CE2-CG2 4.21Å; F339-T347 CarbonylContact O-C 3.54Å; F339-T347 VanDerWaalsContact O-CA 3.3Å; F339-T347 WeakPolarHBondContact O-CA 3.17Å; I340-T347 HydrophobicContact CB-CG2 4.47Å; I340-T347 HydrophobicContact CG1-CG2 4.01Å; I340-T347 HydrophobicContact CG2-CG2 4.27Å
348Q81.5Confident77.1Confident19 Ų1978 Ų789%0.08935%0.353CS..EExtended strand (participates in β ladder)trans-145.1160.8174.161.5-175.65000110W327 F339 E350W327-Q348 HydrophobicContact CH2-CG 4.08Å; W327-Q348 VanDerWaalsContact CH2-NE2 3.34Å; W327-Q348 HydrophobicContact CZ3-CG 3.79Å; F339-Q348 HydrophobicContact CB-CG 4.35Å; F339-Q348 PolarHBondContact N-O 2.6Å; F339-Q348 PolarHBondContact O-N 3.07Å; Q348-E350 WeakPolarHBondContact CG-O 3.07Å; Q348-E350 PolarHBondContact NE2-O 3.22Å
349W80Confident76.1Confident122 Ų12278.5 Ų78.546%0.46236%0.357SS..SBendtrans-89.8-17.7177.8-63.2100.4000111.4H332 R336 F338H332-W349 HydrophobicContact CB-CH2 3.97Å; H332-W349 HydrophobicContact CB-CZ3 4.13Å; H332-W349 AromaticContact CG-CH2 3.89Å; R336-W349 HydrophobicContact CB-CE3 4.33Å; R336-W349 HydrophobicContact CB-CH2 4.48Å; R336-W349 HydrophobicContact CB-CZ3 3.65Å; F338-W349 HydrophobicContact CB-CD2 4.25Å; F338-W349 HydrophobicContact CB-CE3 3.64Å; F338-W349 HydrophobicContact CB-CH2 4.42Å; F338-W349 HydrophobicContact CB-CZ3 3.74Å; F338-W349 HydrophobicContact CG-CZ3 4.49Å
350E77.5Confident74.6Confident108 Ų10878.7 Ų78.751%0.50536%0.359SS..SBendtrans-83.9131.8-178.4-64.671.5-15700112F339 Q348F339-E350 VanDerWaalsContact CD2-C 3.48Å; F339-E350 WeakPolarHBondContact CD2-O 3.45Å; Q348-E350 WeakPolarHBondContact CG-O 3.07Å; Q348-E350 PolarHBondContact NE2-O 3.22Å
351D81Confident73.1Confident4 Ų478.5 Ų78.52%0.02136%0.362CS..  trans-63.3123173.5-167.8-39.5000110.4F339 R353 F354F339-D351 HydrophobicContact CD2-CB 4.37Å; F339-D351 HydrophobicContact CE1-CB 4.19Å; F339-D351 HydrophobicContact CE2-CB 3.67Å; F339-D351 HydrophobicContact CZ-CB 3.55Å; F339-D351 WeakPolarHBondContact CZ-OD2 3.36Å; D351-R353 PolarHBondContact O-N 3.46Å; D351-R353 VanDerWaalsContact O-N 3.1Å; D351-R353 WeakPolarHBondContact OD1-CB 3.28Å; D351-R353 VanDerWaalsContact OD1-CG 3.3Å; D351-R353 WeakPolarHBondContact OD1-CG 3.24Å; D351-R353 IonicContact OD1-CZ 2.92Å; D351-R353 PolarHBondContact OD1-N 3.02Å; D351-R353 IonicContact OD1-NE 3.12Å; D351-R353 PolarHBondContact OD1-NE 2.81Å; D351-R353 IonicContact OD1-NH2 2.84Å; D351-R353 IonicContact OD2-CZ 2.64Å; D351-R353 VanDerWaalsContact OD2-CZ 3.25Å; D351-R353 IonicContact OD2-NE 3.98Å; D351-R353 PolarHBondContact OD2-NE 2.64Å; D351-R353 IonicContact OD2-NH2 3.75Å; D351-R353 PolarHBondContact OD2-NH2 3.19Å; D351-F354 HydrophobicContact CB-CD2 3.83Å; D351-F354 HydrophobicContact CB-CE2 3.96Å; D351-F354 WeakPolarHBondContact O-CD2 3.43Å; D351-F354 PolarHBondContact O-N 3.01Å; D351-F354 VanDerWaalsContact O-N 3.15Å
352P81.2Confident71.5Confident4 Ų481.6 Ų81.63%0.02638%0.383CS..G310 helixtrans-62.1-18.8-179.629.2-39.6000113.3L323 P324 W327 F354 E355L323-P352 HydrophobicContact CD2-CG 3.94Å; P324-P352 HydrophobicContact CG-CB 4.23Å; P324-P352 HydrophobicContact CG-CG 4.29Å; W327-P352 HydrophobicContact CB-CG 4.31Å; W327-P352 HydrophobicContact CD2-CB 3.59Å; W327-P352 HydrophobicContact CD2-CG 3.51Å; W327-P352 VanDerWaalsContact CE2-CB 3.49Å; W327-P352 HydrophobicContact CE3-CB 3.79Å; W327-P352 HydrophobicContact CE3-CG 3.55Å; W327-P352 HydrophobicContact CG-CB 4.21Å; W327-P352 HydrophobicContact CG-CG 3.87Å; W327-P352 HydrophobicContact CH2-CB 3.79Å; W327-P352 HydrophobicContact CH2-CG 4.44Å; W327-P352 HydrophobicContact CZ2-CB 3.6Å; W327-P352 HydrophobicContact CZ2-CG 4.43Å; W327-P352 HydrophobicContact CZ3-CB 3.88Å; W327-P352 HydrophobicContact CZ3-CG 4.03Å; P352-F354 PolarHBondContact O-N 3.09Å; P352-E355 WeakPolarHBondContact O-CB 3.49Å; P352-E355 PolarHBondContact O-N 2.9Å
353R80.9Confident70.1Confident3 Ų380.8 Ų80.81%0.01139%0.392CS..G310 helixtrans-66-17.5177.6-63.4171.9-74.3-163.3-1.4112.6D318 G321 D351 E355 N356 I359D318-R353 IonicContact OD2-CZ 2.8Å; D318-R353 IonicContact OD2-NH1 2.64Å; D318-R353 PolarHBondContact OD2-NH1 2.91Å; D318-R353 IonicContact OD2-NH2 3.23Å; D318-R353 PolarHBondContact OD2-NH2 3.42Å; G321-R353 PolarHBondContact O-NH1 3.18Å; D351-R353 PolarHBondContact O-N 3.46Å; D351-R353 VanDerWaalsContact O-N 3.1Å; D351-R353 WeakPolarHBondContact OD1-CB 3.28Å; D351-R353 VanDerWaalsContact OD1-CG 3.3Å; D351-R353 WeakPolarHBondContact OD1-CG 3.24Å; D351-R353 IonicContact OD1-CZ 2.92Å; D351-R353 PolarHBondContact OD1-N 3.02Å; D351-R353 IonicContact OD1-NE 3.12Å; D351-R353 PolarHBondContact OD1-NE 2.81Å; D351-R353 IonicContact OD1-NH2 2.84Å; D351-R353 IonicContact OD2-CZ 2.64Å; D351-R353 VanDerWaalsContact OD2-CZ 3.25Å; D351-R353 IonicContact OD2-NE 3.98Å; D351-R353 PolarHBondContact OD2-NE 2.64Å; D351-R353 IonicContact OD2-NH2 3.75Å; D351-R353 PolarHBondContact OD2-NH2 3.19Å; R353-E355 PolarHBondContact O-N 2.87Å; R353-N356 PolarHBondContact O-N 2.83Å; R353-I359 HydrophobicContact CB-CD1 4.41Å
354F69.1Low68.9Low21 Ų2178.7 Ų78.79%0.09238%0.384CS..G310 helixtrans-66.8-21.6168.9-78.2-78.2000113.7D351 P352 V609 K613 W633 L637D351-F354 HydrophobicContact CB-CD2 3.83Å; D351-F354 HydrophobicContact CB-CE2 3.96Å; D351-F354 WeakPolarHBondContact O-CD2 3.43Å; D351-F354 PolarHBondContact O-N 3.01Å; D351-F354 VanDerWaalsContact O-N 3.15Å; P352-F354 PolarHBondContact O-N 3.09Å; F354-V609 HydrophobicContact CE1-CG1 3.99Å; F354-K613 HydrophobicContact CD1-CD 4.47Å; F354-K613 HydrophobicContact CE1-CD 3.89Å; F354-K613 HydrophobicContact CZ-CD 4.01Å; F354-W633 HydrophobicContact CZ-CB 3.86Å; F354-L637 HydrophobicContact CD1-CD1 3.72Å; F354-L637 HydrophobicContact CD1-CD2 3.83Å; F354-L637 HydrophobicContact CD1-CG 4Å; F354-L637 HydrophobicContact CD2-CD1 3.68Å; F354-L637 HydrophobicContact CE1-CD1 3.36Å; F354-L637 HydrophobicContact CE1-CD2 3.69Å; F354-L637 HydrophobicContact CE1-CG 3.44Å; F354-L637 VanDerWaalsContact CE1-CG 3.44Å; F354-L637 HydrophobicContact CE2-CD1 3.31Å; F354-L637 HydrophobicContact CE2-CG 4.26Å; F354-L637 HydrophobicContact CG-CD1 3.84Å; F354-L637 HydrophobicContact CZ-CD1 3.1Å; F354-L637 HydrophobicContact CZ-CD2 4.3Å; F354-L637 HydrophobicContact CZ-CG 3.55Å
355E66.7Low67.3Low114 Ų11476.9 Ų76.953%0.53339%0.393SS..G310 helixtrans-85.3-13.7177.4-60.7-174.9172.500112.3P352 R353 E357P352-E355 WeakPolarHBondContact O-CB 3.49Å; P352-E355 PolarHBondContact O-N 2.9Å; R353-E355 PolarHBondContact O-N 2.87Å; E355-E357 PolarHBondContact O-N 2.83Å
356N66.8Low66.2Low64 Ų6469.1 Ų69.134%0.34236%0.364SS..  trans-78.5105.4177.6-169.7-5.5000110.2R353 N358 I359 A360R353-N356 PolarHBondContact O-N 2.83Å; N356-N358 PolarHBondContact O-N 2.81Å; N356-N358 VanDerWaalsContact O-N 3.14Å; N356-N358 WeakPolarHBondContact OD1-CB 3.41Å; N356-N358 PolarHBondContact OD1-N 2.84Å; N356-I359 HydrophobicContact CB-CB 4.48Å; N356-I359 HydrophobicContact CB-CD1 4.18Å; N356-I359 HydrophobicContact CB-CG1 4.3Å; N356-I359 PolarHBondContact O-N 3Å; N356-A360 PolarHBondContact O-N 2.72Å
357E56.1Low65Low138 Ų13865.2 Ų65.265%0.64536%0.357SS*.Hα-helixtrans-55.6-29.4178.5-66.6-176.7170.300112.8E355 I359 G361E355-E357 PolarHBondContact O-N 2.83Å; E357-I359 VanDerWaalsContact C-N 3.26Å; E357-I359 PolarHBondContact O-N 3.12Å; E357-G361 CarbonylContact O-C 3.59Å; E357-G361 VanDerWaalsContact O-C 3.3Å; E357-G361 VanDerWaalsContact O-CA 3.25Å; E357-G361 WeakPolarHBondContact O-CA 3.15Å; E357-G361 PolarHBondContact O-N 3.36Å
358N58.4Low63.6Low154 Ų15472.6 Ų72.682%0.82438%0.375SS*.Hα-helixtrans-67.5-24.4177.6-66.4-24.6000113.1N356N356-N358 PolarHBondContact O-N 2.81Å; N356-N358 VanDerWaalsContact O-N 3.14Å; N356-N358 WeakPolarHBondContact OD1-CB 3.41Å; N356-N358 PolarHBondContact OD1-N 2.84Å
359I58.4Low63.2Low46 Ų4675.3 Ų75.324%0.23639%0.39CS..Hα-helixtrans-102.4-42.7-178.4-57.3175.2000110.7R353 N356 E357 L637 R644R353-I359 HydrophobicContact CB-CD1 4.41Å; N356-I359 HydrophobicContact CB-CB 4.48Å; N356-I359 HydrophobicContact CB-CD1 4.18Å; N356-I359 HydrophobicContact CB-CG1 4.3Å; N356-I359 PolarHBondContact O-N 3Å; E357-I359 VanDerWaalsContact C-N 3.26Å; E357-I359 PolarHBondContact O-N 3.12Å; I359-L637 HydrophobicContact CG2-CD2 4.38Å; I359-R644 PolarHBondContact O-NH1 2.81Å; I359-R644 PolarHBondContact O-NH2 2.97Å
360A56.1Low62.8Low4 Ų470 Ų703%0.03337%0.37CS..Hα-helixtrans-78.2-20-178.900000113.4N356 V609N356-A360 PolarHBondContact O-N 2.72Å; A360-V609 PolarHBondContact O-N 2.88Å
361G53.9Low62.5Low19 Ų1969.2 Ų69.220%0.19637%0.365CS..  trans91.2144.6-17300000112E357E357-G361 CarbonylContact O-C 3.59Å; E357-G361 VanDerWaalsContact O-C 3.3Å; E357-G361 VanDerWaalsContact O-CA 3.25Å; E357-G361 WeakPolarHBondContact O-CA 3.15Å; E357-G361 PolarHBondContact O-N 3.36Å
362P51Low62.3Low67 Ų6777.3 Ų77.344%0.43540%0.395SS..PPolyproline II helixtrans-72.2142.1175.128.7-33.1000111.1V364P362-V364 PolarHBondContact O-N 2.88Å
363A49.1Very low62.3Low78 Ų7879.8 Ų79.865%0.64541%0.406SS*.PPolyproline II helixtrans-66.4119.5167.300000109.2P365A363-P365 VanDerWaalsContact O-CD 3.31Å; A363-P365 WeakPolarHBondContact O-CD 3.16Å
364V53.2Low62.2Low70 Ų7080.4 Ų80.442%0.42441%0.409SS..PPolyproline II helixtrans-72.2119.6-179.2-171.70000109.6P362 Y366P362-V364 PolarHBondContact O-N 2.88Å; V364-Y366 HydrophobicContact CB-CE1 4.19Å; V364-Y366 HydrophobicContact CB-CE2 3.86Å; V364-Y366 WeakPolarHBondContact CB-OH 3.19Å; V364-Y366 HydrophobicContact CG1-CD1 4.34Å; V364-Y366 HydrophobicContact CG1-CE1 3.5Å; V364-Y366 HydrophobicContact CG1-CE2 4.12Å; V364-Y366 VanDerWaalsContact CG1-CZ 3.4Å; V364-Y366 VanDerWaalsContact CG1-OH 3.29Å; V364-Y366 WeakPolarHBondContact CG1-OH 3.39Å; V364-Y366 WeakPolarHBondContact O-CD2 3.21Å; V364-Y366 PolarHBondContact O-N 3.38Å
365P47.4Very low62.9Low123 Ų12384.2 Ų84.280%0.79943%0.428SS*.  trans-78.8115.9-177.828.6-30.1000110.9A363A363-P365 VanDerWaalsContact O-CD 3.31Å; A363-P365 WeakPolarHBondContact O-CD 3.16Å
366Y55.9Low63.8Low72 Ų7284 Ų8428%0.28242%0.422SS..  trans-103.8160.2-179.5-65.6-57.3000114.6V364 R368 L599 L604 M659V364-Y366 HydrophobicContact CB-CE1 4.19Å; V364-Y366 HydrophobicContact CB-CE2 3.86Å; V364-Y366 WeakPolarHBondContact CB-OH 3.19Å; V364-Y366 HydrophobicContact CG1-CD1 4.34Å; V364-Y366 HydrophobicContact CG1-CE1 3.5Å; V364-Y366 HydrophobicContact CG1-CE2 4.12Å; V364-Y366 VanDerWaalsContact CG1-CZ 3.4Å; V364-Y366 VanDerWaalsContact CG1-OH 3.29Å; V364-Y366 WeakPolarHBondContact CG1-OH 3.39Å; V364-Y366 WeakPolarHBondContact O-CD2 3.21Å; V364-Y366 PolarHBondContact O-N 3.38Å; Y366-R368 PolarHBondContact O-N 2.96Å; Y366-L599 HydrophobicContact CD1-CD1 3.55Å; Y366-L599 HydrophobicContact CE1-CD1 3.1Å; Y366-L599 HydrophobicContact CE1-CD2 3.8Å; Y366-L599 HydrophobicContact CE1-CG 4.07Å; Y366-L599 WeakPolarHBondContact OH-CD2 3.41Å; Y366-L604 HydrophobicContact CE2-CD2 3.85Å; Y366-L604 WeakPolarHBondContact OH-CD2 3.26Å; Y366-M659 HydrophobicContact CD1-CE 3.69Å; Y366-M659 HydrophobicContact CD1-CG 4.4Å; Y366-M659 HydrophobicContact CD1-SD 4.29Å; Y366-M659 HydrophobicContact CD2-CE 4.15Å; Y366-M659 HydrophobicContact CD2-CG 3.75Å; Y366-M659 HydrophobicContact CD2-SD 3.64Å; Y366-M659 HydrophobicContact CE1-CE 4.18Å; Y366-M659 HydrophobicContact CE1-CG 4.2Å; Y366-M659 HydrophobicContact CE2-CG 3.44Å; Y366-M659 VanDerWaalsContact CE2-CG 3.44Å; Y366-M659 HydrophobicContact CE2-SD 4.01Å; Y366-M659 HydrophobicContact CG-CE 3.69Å; Y366-M659 HydrophobicContact CG-CG 4.21Å; Y366-M659 HydrophobicContact CG-SD 3.78Å
367S55.9Low64.7Low50 Ų5082.7 Ų82.735%0.3542%0.415SS..  trans-48.4119.8166.2164.90000110.8D369 Y370 E596S367-D369 PolarHBondContact O-N 3.2Å; S367-Y370 PolarHBondContact O-N 3.26Å; S367-E596 VanDerWaalsContact CB-OE1 3.31Å; S367-E596 WeakPolarHBondContact CB-OE1 3.45Å; S367-E596 PolarHBondContact OG-OE1 3.07Å
368R56.4Low66Low244 Ų24481.3 Ų81.392%0.92140%0.404SS*.THydrogen-bonded Turntrans-55-21.7-178.1-7317968.5-173.71.9113.5Y366Y366-R368 PolarHBondContact O-N 2.96Å
369D71.6Confident67.3Low76 Ų7678.1 Ų78.141%0.40639%0.394SS..THydrogen-bonded Turntrans-102.3-4.8-176.9-67.8-51.3000114.3S367 K371 R372 K373S367-D369 PolarHBondContact O-N 3.2Å; D369-K371 VanDerWaalsContact C-N 3.31Å; D369-K371 PolarHBondContact O-N 2.97Å; D369-R372 WeakPolarHBondContact O-CA 3.38Å; D369-R372 WeakPolarHBondContact O-CB 3.39Å; D369-R372 PolarHBondContact O-N 2.89Å; D369-R372 IonicContact OD1-NH1 3.81Å; D369-R372 PolarHBondContact OD1-NH1 3.07Å; D369-K373 PolarHBondContact O-N 2.96Å
370Y71.5Confident68.8Low11 Ų1184.1 Ų84.14%0.04341%0.414CS..Hα-helixtrans-55.2-44.6-176173.8-98.3000112.9S367 R372 K373 V374 F592 E596 L600 M659S367-Y370 PolarHBondContact O-N 3.26Å; Y370-R372 VanDerWaalsContact C-N 3.26Å; Y370-R372 PolarHBondContact O-N 2.94Å; Y370-K373 CarbonylContact O-C 3.55Å; Y370-K373 WeakPolarHBondContact O-CA 3.23Å; Y370-K373 WeakPolarHBondContact O-CB 3.47Å; Y370-K373 PolarHBondContact O-N 3.33Å; Y370-V374 HydrophobicContact CD1-CG2 3.82Å; Y370-V374 HydrophobicContact CD2-CG2 4.21Å; Y370-V374 HydrophobicContact CE1-CG2 3.29Å; Y370-V374 HydrophobicContact CE2-CG2 3.72Å; Y370-V374 HydrophobicContact CG-CG2 4.29Å; Y370-V374 PolarHBondContact O-N 3.48Å; Y370-F592 HydrophobicContact CD2-CD1 4.45Å; Y370-F592 HydrophobicContact CD2-CE1 4.32Å; Y370-F592 HydrophobicContact CE2-CD1 4.28Å; Y370-F592 HydrophobicContact CE2-CE1 4.07Å; Y370-E596 HydrophobicContact CD2-CB 3.78Å; Y370-E596 HydrophobicContact CD2-CG 3.69Å; Y370-E596 HydrophobicContact CE2-CB 3.87Å; Y370-E596 HydrophobicContact CE2-CG 4.29Å; Y370-E596 WeakPolarHBondContact CE2-O 3.17Å; Y370-L600 WeakPolarHBondContact OH-CA 3.48Å; Y370-L600 WeakPolarHBondContact OH-CB 3.46Å; Y370-L600 PolarHBondContact OH-N 3.4Å; Y370-M659 HydrophobicContact CD1-CE 3.08Å; Y370-M659 HydrophobicContact CD1-SD 3.22Å; Y370-M659 WeakPolarHBondContact CD1-SD 3.34Å; Y370-M659 HydrophobicContact CD2-CE 3.63Å; Y370-M659 HydrophobicContact CE1-CB 4.29Å; Y370-M659 HydrophobicContact CE1-CE 3.22Å; Y370-M659 HydrophobicContact CE1-CG 4.3Å; Y370-M659 HydrophobicContact CE1-SD 3.31Å; Y370-M659 WeakPolarHBondContact CE1-SD 3.37Å; Y370-M659 HydrophobicContact CE2-CE 3.77Å; Y370-M659 HydrophobicContact CG-CE 3.26Å; Y370-M659 HydrophobicContact CG-SD 4Å
371K72.6Confident70.3Confident91 Ų9186.2 Ų86.240%0.39642%0.424SS..Hα-helixtrans-55.7-44.4178.1-173.1-179.8-176.6-175.20111.5D369 K373 V374 E375 E664D369-K371 VanDerWaalsContact C-N 3.31Å; D369-K371 PolarHBondContact O-N 2.97Å; K371-K373 VanDerWaalsContact C-N 3.32Å; K371-K373 PolarHBondContact O-N 3.03Å; K371-V374 PolarHBondContact O-N 2.65Å; K371-E375 WeakPolarHBondContact CE-OE1 3.31Å; K371-E375 WeakPolarHBondContact O-CB 3.47Å; K371-E375 WeakPolarHBondContact O-CG 3.49Å; K371-E375 PolarHBondContact O-N 3.34Å; K371-E664 IonicContact NZ-OE1 2.71Å
372R76.6Confident71.9Confident174 Ų17488.9 Ų88.966%0.65744%0.438SS*.Hα-helixtrans-63.8-37.8175.5-67.1175.7174.2169.4-7.7111.4D369 Y370 Y376D369-R372 WeakPolarHBondContact O-CA 3.38Å; D369-R372 WeakPolarHBondContact O-CB 3.39Å; D369-R372 PolarHBondContact O-N 2.89Å; D369-R372 IonicContact OD1-NH1 3.81Å; D369-R372 PolarHBondContact OD1-NH1 3.07Å; Y370-R372 VanDerWaalsContact C-N 3.26Å; Y370-R372 PolarHBondContact O-N 2.94Å; R372-Y376 WeakPolarHBondContact O-CB 3.43Å; R372-Y376 PolarHBondContact O-N 2.94Å
373K80.5Confident73.5Confident57 Ų5794.2 Ų94.225%0.24845%0.454CS..Hα-helixtrans-64.4-41.9175-64.6177.8179.71750112.3D369 Y370 K371 Y376 L377 F592 E596D369-K373 PolarHBondContact O-N 2.96Å; Y370-K373 CarbonylContact O-C 3.55Å; Y370-K373 WeakPolarHBondContact O-CA 3.23Å; Y370-K373 WeakPolarHBondContact O-CB 3.47Å; Y370-K373 PolarHBondContact O-N 3.33Å; K371-K373 VanDerWaalsContact C-N 3.32Å; K371-K373 PolarHBondContact O-N 3.03Å; K373-Y376 PolarHBondContact O-N 2.93Å; K373-L377 WeakPolarHBondContact O-CB 3.41Å; K373-L377 PolarHBondContact O-N 3.02Å; K373-F592 HydrophobicContact CB-CD1 4.39Å; K373-F592 HydrophobicContact CB-CE1 3.7Å; K373-F592 HydrophobicContact CB-CZ 4.25Å; K373-F592 HydrophobicContact CD-CD1 4.34Å; K373-F592 HydrophobicContact CD-CE1 4.44Å; K373-E596 IonicContact NZ-OE1 2.68Å; K373-E596 PolarHBondContact NZ-OE1 3.34Å; K373-E596 IonicContact NZ-OE2 2.65Å; K373-E596 PolarHBondContact NZ-OE2 3.3Å
374V79.8Confident75Confident15 Ų1592.5 Ų92.59%0.09144%0.437CS..Hα-helixtrans-66.6-45.1176.2174.60000111.3Y370 K371 Y376 L377 R378 F592 L600Y370-V374 HydrophobicContact CD1-CG2 3.82Å; Y370-V374 HydrophobicContact CD2-CG2 4.21Å; Y370-V374 HydrophobicContact CE1-CG2 3.29Å; Y370-V374 HydrophobicContact CE2-CG2 3.72Å; Y370-V374 HydrophobicContact CG-CG2 4.29Å; Y370-V374 PolarHBondContact O-N 3.48Å; K371-V374 PolarHBondContact O-N 2.65Å; V374-Y376 VanDerWaalsContact C-N 3.3Å; V374-Y376 PolarHBondContact O-N 2.65Å; V374-L377 PolarHBondContact O-N 3.3Å; V374-R378 WeakPolarHBondContact O-CB 3.18Å; V374-R378 WeakPolarHBondContact O-CG 3.18Å; V374-R378 PolarHBondContact O-N 3.09Å; V374-F592 HydrophobicContact CG2-CE1 4.49Å; V374-L600 HydrophobicContact CG2-CD1 4.32Å
375E83Confident75.9Confident102 Ų10295.1 Ų95.148%0.47745%0.448SS..Hα-helixtrans-60.3-42.9174.6-73.7171.5179.100111K371 R378 S379K371-E375 WeakPolarHBondContact CE-OE1 3.31Å; K371-E375 WeakPolarHBondContact O-CB 3.47Å; K371-E375 WeakPolarHBondContact O-CG 3.49Å; K371-E375 PolarHBondContact O-N 3.34Å; E375-R378 PolarHBondContact O-N 2.96Å; E375-S379 WeakPolarHBondContact O-CB 3.31Å; E375-S379 PolarHBondContact O-N 3.15Å
376Y84.6Confident77.2Confident108 Ų10891.8 Ų91.842%0.42443%0.428SS..Hα-helixtrans-61.3-49.3174.6179.9-101.8000111.8R372 K373 V374 R378 S379 R380 L591R372-Y376 WeakPolarHBondContact O-CB 3.43Å; R372-Y376 PolarHBondContact O-N 2.94Å; K373-Y376 PolarHBondContact O-N 2.93Å; V374-Y376 VanDerWaalsContact C-N 3.3Å; V374-Y376 PolarHBondContact O-N 2.65Å; Y376-R378 PolarHBondContact O-N 2.79Å; Y376-S379 WeakPolarHBondContact O-CB 3.22Å; Y376-S379 PolarHBondContact O-N 3.41Å; Y376-S379 VanDerWaalsContact O-N 3.15Å; Y376-S379 PolarHBondContact O-OG 2.94Å; Y376-R380 HydrophobicContact CD1-CG 4.48Å; Y376-R380 HydrophobicContact CE1-CG 4.06Å; Y376-R380 HydrophobicContact CE2-CG 4.16Å; Y376-R380 WeakPolarHBondContact O-CG 3.38Å; Y376-R380 PolarHBondContact O-N 2.78Å; Y376-R380 VanDerWaalsContact O-N 3.13Å; Y376-R380 PolarHBondContact OH-NE 2.84Å; Y376-R380 VanDerWaalsContact OH-NE 3.13Å; Y376-R380 PolarHBondContact OH-NH2 3.4Å; Y376-L591 HydrophobicContact CD1-CD2 4.38Å
377L86Confident77.8Confident37 Ų3796.5 Ų96.519%0.19446%0.458CS..Hα-helixtrans-54.1-53.3175.617567.5000110.5K373 V374 S379 R380 L381 I493 F592 L600K373-L377 WeakPolarHBondContact O-CB 3.41Å; K373-L377 PolarHBondContact O-N 3.02Å; V374-L377 PolarHBondContact O-N 3.3Å; L377-S379 VanDerWaalsContact C-N 3.26Å; L377-S379 PolarHBondContact O-N 3.23Å; L377-R380 CarbonylContact O-C 3.6Å; L377-R380 WeakPolarHBondContact O-CA 3.14Å; L377-R380 PolarHBondContact O-N 2.96Å; L377-L381 HydrophobicContact CD1-CD2 4.32Å; L377-L381 WeakPolarHBondContact O-CG 3.3Å; L377-L381 PolarHBondContact O-N 3.19Å; L377-I493 HydrophobicContact CD2-CG2 4.1Å; L377-F592 HydrophobicContact CB-CE2 4.35Å; L377-F592 HydrophobicContact CB-CZ 4.08Å; L377-F592 HydrophobicContact CD1-CE2 4.44Å; L377-F592 HydrophobicContact CD2-CE2 3.87Å; L377-F592 HydrophobicContact CD2-CZ 3.91Å; L377-F592 HydrophobicContact CG-CE2 4.44Å; L377-L600 HydrophobicContact CD2-CD2 3.88Å
378R84.9Confident78.5Confident109 Ų10998.7 Ų98.741%0.41147%0.473SS..Hα-helixtrans-58.5-37.1179.1-74.5179.1173.5175.2-3.8112.6V374 E375 Y376 R380 L381 Y666V374-R378 WeakPolarHBondContact O-CB 3.18Å; V374-R378 WeakPolarHBondContact O-CG 3.18Å; V374-R378 PolarHBondContact O-N 3.09Å; E375-R378 PolarHBondContact O-N 2.96Å; Y376-R378 PolarHBondContact O-N 2.79Å; R378-R380 PolarHBondContact O-N 3.1Å; R378-L381 PolarHBondContact O-N 2.92Å; R378-Y666 VanDerWaalsContact CZ-OH 3.3Å; R378-Y666 PolarHBondContact NH1-OH 3.05Å; R378-Y666 PolarHBondContact NH2-OH 3.09Å
379S85.1Confident79.6Confident87 Ų8787.9 Ų87.961%0.60844%0.438SS*.Hα-helixtrans-67.4-2317680.50000113.5E375 Y376 L377E375-S379 WeakPolarHBondContact O-CB 3.31Å; E375-S379 PolarHBondContact O-N 3.15Å; Y376-S379 WeakPolarHBondContact O-CB 3.22Å; Y376-S379 PolarHBondContact O-N 3.41Å; Y376-S379 VanDerWaalsContact O-N 3.15Å; Y376-S379 PolarHBondContact O-OG 2.94Å; L377-S379 VanDerWaalsContact C-N 3.26Å; L377-S379 PolarHBondContact O-N 3.23Å
380R88.8Confident80.3Confident172 Ų17290.4 Ų90.465%0.64945%0.445SS*.Hα-helixtrans-97.1-12.7-179.8-66.6-61.5-165.8178.92.4113.7Y376 L377 R378Y376-R380 HydrophobicContact CD1-CG 4.48Å; Y376-R380 HydrophobicContact CE1-CG 4.06Å; Y376-R380 HydrophobicContact CE2-CG 4.16Å; Y376-R380 WeakPolarHBondContact O-CG 3.38Å; Y376-R380 PolarHBondContact O-N 2.78Å; Y376-R380 VanDerWaalsContact O-N 3.13Å; Y376-R380 PolarHBondContact OH-NE 2.84Å; Y376-R380 VanDerWaalsContact OH-NE 3.13Å; Y376-R380 PolarHBondContact OH-NH2 3.4Å; L377-R380 CarbonylContact O-C 3.6Å; L377-R380 WeakPolarHBondContact O-CA 3.14Å; L377-R380 PolarHBondContact O-N 2.96Å; R378-R380 PolarHBondContact O-N 3.1Å
381L88.4Confident81.2Confident49 Ų4990 Ų9026%0.25744%0.444SS..SBendtrans-65.9135.5178.5-71.3178.2000110.9L377 R378 K383 Y494L377-L381 HydrophobicContact CD1-CD2 4.32Å; L377-L381 WeakPolarHBondContact O-CG 3.3Å; L377-L381 PolarHBondContact O-N 3.19Å; R378-L381 PolarHBondContact O-N 2.92Å; L381-K383 PolarHBondContact O-N 3.19Å; L381-Y494 HydrophobicContact CB-CD2 4.25Å; L381-Y494 HydrophobicContact CB-CE2 4.15Å; L381-Y494 HydrophobicContact CD1-CD2 3.97Å; L381-Y494 HydrophobicContact CD2-CD2 4.3Å; L381-Y494 HydrophobicContact CG-CD2 4.4Å
382P87.5Confident82.1Confident74 Ų7489.8 Ų89.848%0.48145%0.447SS..PPolyproline II helixtrans-60.2133.9176.8-21.732000111.2Y494P382-Y494 VanDerWaalsContact O-CE2 3.27Å; P382-Y494 WeakPolarHBondContact O-CE2 3.35Å; P382-Y494 PolarHBondContact O-OH 3.07Å
383K84.4Confident82.8Confident179 Ų17981.6 Ų81.678%0.77842%0.416SS*.PPolyproline II helixtrans-73.4154.3175.9-66.4-175.1-178.2-179.70111.1L381L381-K383 PolarHBondContact O-N 3.19Å
384P80.6Confident83.3Confident43 Ų4381.6 Ų81.628%0.27942%0.421SS..PPolyproline II helixtrans-61.7145.2170.825.4-31.9000110.6S386P384-S386 PolarHBondContact O-N 3.19Å
385N72.7Confident83.9Confident125 Ų12580.9 Ų80.967%0.66842%0.416SS*.SBendtrans-64.5-26.1-178.2-72.6-5.5000112.5
386S74.3Confident84.2Confident52 Ų5279.4 Ų79.436%0.36441%0.409SS..  trans-136.8132.2177.51780000110.4P384 S388 G389P384-S386 PolarHBondContact O-N 3.19Å; S386-S388 PolarHBondContact O-N 3.27Å; S386-S388 PolarHBondContact OG-N 3.48Å; S386-S388 PolarHBondContact OG-OG 2.83Å; S386-G389 PolarHBondContact O-N 3.4Å; S386-G389 VanDerWaalsContact O-N 3.08Å
387N68.2Low84.3Confident171 Ų17178.6 Ų78.691%0.91441%0.405SS*.THydrogen-bonded Turntrans-62.7-20.1173.7-71.713.3000112.7
388S70.7Confident84.2Confident97 Ų9782.8 Ų82.868%0.67843%0.428SS*.THydrogen-bonded Turntrans-105.57.5177.370.90000113.2S386 K390S386-S388 PolarHBondContact O-N 3.27Å; S386-S388 PolarHBondContact OG-N 3.48Å; S386-S388 PolarHBondContact OG-OG 2.83Å; S388-K390 PolarHBondContact O-N 3.22Å
389G80.3Confident84.3Confident16 Ų1680 Ų8017%0.16542%0.424CS..  trans-62.7131.6174.700000110S386 N418 K419S386-G389 PolarHBondContact O-N 3.4Å; S386-G389 VanDerWaalsContact O-N 3.08Å; G389-N418 WeakPolarHBondContact O-CB 3.4Å; G389-K419 PolarHBondContact O-N 2.82Å
390K86.7Confident84.6Confident129 Ų12976.3 Ų76.356%0.56140%0.397SS*.EExtended strand (participates in β ladder)trans-116.4147.3172.2-10.8179-172.41740108.9S388 K419S388-K390 PolarHBondContact O-N 3.22Å; K390-K419 WeakPolarHBondContact CA-O 3.27Å
391C90.6Very high84.6Confident3 Ų368.1 Ų68.12%0.0237%0.366CS..EExtended strand (participates in β ladder)trans-118.189.5172.6176.40000108.1M393 K411 D415 N418 K419 L420 W421C391-M393 WeakPolarHBondContact SG-CE 3.47Å; C391-K411 WeakPolarHBondContact SG-CD 3.41Å; C391-K411 WeakPolarHBondContact SG-CE 3.46Å; C391-D415 WeakPolarHBondContact CB-O 3.34Å; C391-N418 HydrophobicContact CB-CB 4.28Å; C391-K419 PolarHBondContact N-O 2.83Å; C391-L420 HydrophobicContact CB-CD2 3.92Å; C391-W421 PolarHBondContact O-N 3.11Å
392D89.9Confident84.6Confident86 Ų8666.9 Ų66.946%0.4636%0.359SS..EExtended strand (participates in β ladder)trans-78.8134.8-176.8-52.8-48.2000110.6K411 W421D392-K411 WeakPolarHBondContact O-CE 3.38Å; D392-K411 PolarHBondContact O-NZ 2.78Å; D392-W421 CarbonylContact C-O 3.22Å; D392-W421 WeakPolarHBondContact CA-O 3.5Å; D392-W421 WeakPolarHBondContact OD1-CB 3.48Å
393M92.1Very high84.8Confident2 Ų263.6 Ų63.61%0.0134%0.337CS..EExtended strand (participates in β ladder)trans-141.5123.6173-51.2-169.9-168.400109.3C391 H407 I408 K411 L416 W421 I422 E423 W439 M491C391-M393 WeakPolarHBondContact SG-CE 3.47Å; M393-H407 HydrophobicContact CB-CB 4.49Å; M393-H407 HydrophobicContact CG-CB 4.19Å; M393-H407 HydrophobicContact SD-CB 3.98Å; M393-I408 HydrophobicContact CE-CG1 3.99Å; M393-I408 HydrophobicContact SD-CG1 4.22Å; M393-K411 HydrophobicContact CE-CD 4.01Å; M393-L416 HydrophobicContact CE-CD2 3.72Å; M393-W421 PolarHBondContact N-O 3.01Å; M393-I422 HydrophobicContact CB-CD1 3.78Å; M393-I422 HydrophobicContact CG-CD1 3.97Å; M393-I422 WeakPolarHBondContact O-CA 3.49Å; M393-I422 HydrophobicContact SD-CD1 4.01Å; M393-E423 PolarHBondContact O-N 2.87Å; M393-W439 HydrophobicContact SD-CZ2 4.39Å; M393-M491 HydrophobicContact CE-CE 4.05Å
394V91.6Very high85.3Confident57 Ų5755 Ų5535%0.34530%0.3SS..EExtended strand (participates in β ladder)trans-108.4117.3175.7-176.30000107.1H407 E423 F425V394-H407 PolarHBondContact N-NE2 3.24Å; V394-H407 PolarHBondContact O-NE2 2.91Å; V394-E423 CarbonylContact C-O 3.57Å; V394-E423 WeakPolarHBondContact CA-O 3.23Å; V394-E423 HydrophobicContact CG2-CB 4.28Å; V394-F425 HydrophobicContact CG1-CB 4.22Å; V394-F425 HydrophobicContact CG1-CD2 4.29Å
395V92.2Very high85.9Confident0 Ų054.1 Ų54.10%029%0.291CS..EExtended strand (participates in β ladder)trans-125.5146.8-173.5-60.50000110.3L400 D403 I422 E423 F424 F425V395-L400 HydrophobicContact CB-CD1 4.2Å; V395-L400 HydrophobicContact CG2-CD1 3.84Å; V395-D403 HydrophobicContact CB-CB 3.97Å; V395-D403 HydrophobicContact CG1-CB 3.85Å; V395-I422 HydrophobicContact CG2-CG2 4.19Å; V395-E423 PolarHBondContact N-O 2.86Å; V395-F424 HydrophobicContact CG2-CD1 3.79Å; V395-F424 HydrophobicContact CG2-CE1 3.81Å; V395-F424 CarbonylContact O-C 3.58Å; V395-F424 VanDerWaalsContact O-CA 3.27Å; V395-F424 WeakPolarHBondContact O-CA 3.46Å; V395-F425 PolarHBondContact O-N 3.15Å
396H88.9Confident86.9Confident71 Ų7154.6 Ų54.633%0.32928%0.284SS..  trans-92.8147.9170.8-56.171.2000109.2D398 T399 L400 D403 F425H396-D398 VanDerWaalsContact C-N 3.33Å; H396-D398 PolarHBondContact O-N 3.04Å; H396-T399 CarbonylContact O-C 3.46Å; H396-L400 WeakPolarHBondContact O-CA 3.47Å; H396-L400 PolarHBondContact O-N 3.28Å; H396-D403 IonicContact CE1-OD2 3.84Å; H396-D403 IonicContact CG-OD2 3.06Å; H396-D403 PolarHBondContact N-OD2 3Å; H396-D403 IonicContact ND1-OD2 2.91Å; H396-D403 PolarHBondContact ND1-OD2 3.28Å; H396-F425 VanDerWaalsContact CD2-CB 3.5Å; H396-F425 WeakPolarHBondContact CD2-CB 3.38Å; H396-F425 AromaticContact CD2-CD1 3.48Å; H396-F425 VanDerWaalsContact CD2-CD1 3.48Å; H396-F425 WeakPolarHBondContact CD2-CD1 3.32Å; H396-F425 AromaticContact CD2-CG 3.56Å; H396-F425 AromaticContact CE1-CG 3.91Å; H396-F425 AromaticContact NE2-CD1 3.34Å; H396-F425 VanDerWaalsContact NE2-CD1 3.34Å; H396-F425 WeakPolarHBondContact NE2-CD1 3.47Å; H396-F425 AromaticContact NE2-CD2 3.71Å; H396-F425 AromaticContact NE2-CE1 3.93Å; H396-F425 AromaticContact NE2-CG 3.21Å; H396-F425 WeakPolarHBondContact NE2-CG 3.37Å
397R87Confident87.8Confident91 Ų9154.8 Ų54.834%0.34328%0.279SS..SBendtrans-62.2-41.3175.2-68.5-169.9179.1-96.1-5.8111.9T399 L400 F424 E427 E438R397-T399 PolarHBondContact O-N 3.15Å; R397-L400 WeakPolarHBondContact O-CB 3.39Å; R397-F424 HydrophobicContact CG-CD1 3.71Å; R397-F424 HydrophobicContact CG-CE1 4.09Å; R397-F424 HydrophobicContact CG-CG 4.35Å; R397-E427 WeakPolarHBondContact CD-OE1 3.29Å; R397-E427 IonicContact CZ-OE1 4Å; R397-E427 IonicContact CZ-OE2 2.73Å; R397-E427 IonicContact NE-OE1 2.75Å; R397-E427 PolarHBondContact NE-OE1 3.01Å; R397-E427 IonicContact NE-OE2 3.42Å; R397-E427 PolarHBondContact NE-OE2 2.99Å; R397-E427 IonicContact NH2-OE1 3.15Å; R397-E427 IonicContact NH2-OE2 3.38Å; R397-E427 PolarHBondContact NH2-OE2 3.35Å; R397-E438 IonicContact CZ-OE1 3.01Å; R397-E438 IonicContact NH1-OE1 3.26Å; R397-E438 PolarHBondContact NH1-OE1 3.19Å; R397-E438 IonicContact NH2-OE1 2.79Å; R397-E438 PolarHBondContact NH2-OE1 3.01Å; R397-E438 IonicContact NH2-OE2 3.35Å
398D84.4Confident89.1Confident126 Ų12646.7 Ų46.767%0.67424%0.235SC*.THydrogen-bonded Turntrans-71.1-28.6-175.5-60.9-26.3000114.1R97 H396R97-D398 PolarHBondContact NH1-O 2.61Å; H396-D398 VanDerWaalsContact C-N 3.33Å; H396-D398 PolarHBondContact O-N 3.04Å
399T87.2Confident90.3Very high51 Ų5144.9 Ų44.931%0.31322%0.217SC..THydrogen-bonded Turntrans-120.432.6-179.760.70000111.6H396 R397 F401 E402 D403H396-T399 CarbonylContact O-C 3.46Å; R397-T399 PolarHBondContact O-N 3.15Å; T399-F401 VanDerWaalsContact C-N 3.28Å; T399-F401 PolarHBondContact O-N 3.47Å; T399-E402 VanDerWaalsContact C-OE2 3.3Å; T399-E402 WeakPolarHBondContact CA-OE2 2.86Å; T399-E402 PolarHBondContact O-N 2.64Å; T399-D403 WeakPolarHBondContact O-CB 3.28Å; T399-D403 VanDerWaalsContact O-CG 3.23Å; T399-D403 PolarHBondContact O-N 2.92Å; T399-D403 PolarHBondContact OG1-OD1 3.48Å; T399-D403 PolarHBondContact OG1-OD2 3.43Å
400L89.7Confident90.9Very high8 Ų850.8 Ų50.84%0.04225%0.245CC..Hα-helixtrans-54.4-45.2-173.1175.464.7000112.1V395 H396 R397 S404 F424 L442 L443 Q446V395-L400 HydrophobicContact CB-CD1 4.2Å; V395-L400 HydrophobicContact CG2-CD1 3.84Å; H396-L400 WeakPolarHBondContact O-CA 3.47Å; H396-L400 PolarHBondContact O-N 3.28Å; R397-L400 WeakPolarHBondContact O-CB 3.39Å; L400-S404 WeakPolarHBondContact O-CB 3.26Å; L400-S404 PolarHBondContact O-N 2.85Å; L400-S404 PolarHBondContact O-OG 3.39Å; L400-F424 HydrophobicContact CD1-CE1 3.99Å; L400-L442 HydrophobicContact CD2-CB 3.31Å; L400-L442 HydrophobicContact CD2-CD1 4.41Å; L400-L442 HydrophobicContact CD2-CG 4.49Å; L400-L443 HydrophobicContact CD2-CB 4.49Å; L400-Q446 HydrophobicContact CD2-CG 4.39Å
401F89.5Confident91.3Very high1 Ų146.3 Ų46.30%0.00423%0.225CC..Hα-helixtrans-67.4-45.8-176.3-174.3-95.1000111.2L37 T399 S404 Y405 L443 Q446 I447 Y452 Y481 F484L37-F401 HydrophobicContact CD1-CD1 4.05Å; L37-F401 HydrophobicContact CD1-CE1 4.26Å; L37-F401 HydrophobicContact CD2-CE1 4.28Å; T399-F401 VanDerWaalsContact C-N 3.28Å; T399-F401 PolarHBondContact O-N 3.47Å; F401-S404 PolarHBondContact O-N 2.93Å; F401-Y405 VanDerWaalsContact O-CB 3.32Å; F401-Y405 WeakPolarHBondContact O-CB 3.45Å; F401-Y405 PolarHBondContact O-N 2.87Å; F401-L443 HydrophobicContact CB-CD1 4.45Å; F401-L443 HydrophobicContact CD2-CD1 3.87Å; F401-Q446 HydrophobicContact CB-CB 3.99Å; F401-Q446 HydrophobicContact CB-CG 4.43Å; F401-Q446 HydrophobicContact CD2-CB 3.83Å; F401-Q446 HydrophobicContact CG-CB 4.3Å; F401-I447 HydrophobicContact CD2-CG1 4.17Å; F401-I447 HydrophobicContact CE2-CB 4.3Å; F401-I447 HydrophobicContact CE2-CG1 3.68Å; F401-Y452 WeakPolarHBondContact CB-OH 3.46Å; F401-Y452 AromaticContact CD1-CE1 3.96Å; F401-Y452 HydrophobicContact CD1-CE1 3.96Å; F401-Y452 HydrophobicContact CD1-CE2 4.28Å; F401-Y452 AromaticContact CD1-CZ 3.73Å; F401-Y452 HydrophobicContact CD2-CE2 4.2Å; F401-Y452 HydrophobicContact CE1-CD1 4.37Å; F401-Y452 HydrophobicContact CE1-CE1 4.14Å; F401-Y452 HydrophobicContact CE2-CE2 4.45Å; F401-Y452 HydrophobicContact CG-CE2 4.11Å; F401-Y452 AromaticContact CG-CZ 3.83Å; F401-Y481 AromaticContact CE1-CD1 3.65Å; F401-Y481 HydrophobicContact CE1-CD1 3.65Å; F401-Y481 AromaticContact CE1-CE1 3.62Å; F401-Y481 HydrophobicContact CE1-CE1 3.62Å; F401-Y481 AromaticContact CZ-CD1 3.81Å; F401-Y481 HydrophobicContact CZ-CD1 3.81Å; F401-Y481 HydrophobicContact CZ-CE1 4.26Å; F401-F484 HydrophobicContact CD2-CE1 4.26Å; F401-F484 HydrophobicContact CE2-CD1 4.41Å; F401-F484 AromaticContact CE2-CE1 3.76Å; F401-F484 HydrophobicContact CE2-CE1 3.76Å; F401-F484 HydrophobicContact CZ-CD1 4.28Å; F401-F484 HydrophobicContact CZ-CE1 4Å
402E87.5Confident91.3Very high22 Ų2252.2 Ų52.210%0.10325%0.25CS..Hα-helixtrans-70.7-39.9-177.4-62.174.1-16000112.2L37 T399 R406 Y452L37-E402 HydrophobicContact CD1-CG 3.8Å; L37-E402 WeakPolarHBondContact CD1-OE1 3.42Å; T399-E402 VanDerWaalsContact C-OE2 3.3Å; T399-E402 WeakPolarHBondContact CA-OE2 2.86Å; T399-E402 PolarHBondContact O-N 2.64Å; E402-R406 WeakPolarHBondContact O-CG 3.46Å; E402-R406 PolarHBondContact O-N 3.42Å; E402-R406 PolarHBondContact O-NE 3.28Å; E402-Y452 PolarHBondContact OE1-OH 3.49Å
403D92.6Very high91.4Very high5 Ų553 Ų533%0.02725%0.254CS..Hα-helixtrans-64.5-45.5175.4-69.6-0.4000110.3V395 H396 T399 R406 H407V395-D403 HydrophobicContact CB-CB 3.97Å; V395-D403 HydrophobicContact CG1-CB 3.85Å; H396-D403 IonicContact CE1-OD2 3.84Å; H396-D403 IonicContact CG-OD2 3.06Å; H396-D403 PolarHBondContact N-OD2 3Å; H396-D403 IonicContact ND1-OD2 2.91Å; H396-D403 PolarHBondContact ND1-OD2 3.28Å; T399-D403 WeakPolarHBondContact O-CB 3.28Å; T399-D403 VanDerWaalsContact O-CG 3.23Å; T399-D403 PolarHBondContact O-N 2.92Å; T399-D403 PolarHBondContact OG1-OD1 3.48Å; T399-D403 PolarHBondContact OG1-OD2 3.43Å; D403-R406 PolarHBondContact O-N 2.88Å; D403-R406 IonicContact OD1-CZ 3.88Å; D403-R406 IonicContact OD1-NH2 3.32Å; D403-R406 PolarHBondContact OD1-NH2 2.82Å; D403-H407 WeakPolarHBondContact O-CB 3.04Å; D403-H407 PolarHBondContact O-CD2 2.95Å; D403-H407 VanDerWaalsContact O-CD2 3.27Å; D403-H407 PolarHBondContact O-N 2.83Å
404S94.8Very high91.3Very high0 Ų057 Ų570%027%0.27CS..Hα-helixtrans-62.7-45.2177-59.90000111.6L400 F401 R406 H407 I408 W439L400-S404 WeakPolarHBondContact O-CB 3.26Å; L400-S404 PolarHBondContact O-N 2.85Å; L400-S404 PolarHBondContact O-OG 3.39Å; F401-S404 PolarHBondContact O-N 2.93Å; S404-R406 PolarHBondContact O-N 2.86Å; S404-H407 PolarHBondContact O-N 3.2Å; S404-I408 WeakPolarHBondContact O-CB 3.07Å; S404-I408 WeakPolarHBondContact O-CG1 3.22Å; S404-I408 PolarHBondContact O-N 3.15Å; S404-W439 PolarHBondContact OG-NE1 3.44Å
405Y93.3Very high91.3Very high24 Ų2456.4 Ų56.49%0.09427%0.265CS..Hα-helixtrans-56-51.8175.8176.5-91.8000111.4L36 F401 H407 I408 M409 S480 Y481 F484L36-Y405 HydrophobicContact CD2-CD1 3.97Å; L36-Y405 HydrophobicContact CD2-CE1 3.65Å; F401-Y405 VanDerWaalsContact O-CB 3.32Å; F401-Y405 WeakPolarHBondContact O-CB 3.45Å; F401-Y405 PolarHBondContact O-N 2.87Å; Y405-H407 PolarHBondContact O-N 3.48Å; Y405-I408 PolarHBondContact O-N 2.78Å; Y405-M409 HydrophobicContact CD1-CG 4.48Å; Y405-M409 HydrophobicContact CD2-CG 3.98Å; Y405-M409 HydrophobicContact CE1-CG 4.31Å; Y405-M409 HydrophobicContact CE2-CG 3.78Å; Y405-M409 HydrophobicContact CG-CG 4.33Å; Y405-M409 VanDerWaalsContact O-CB 3.27Å; Y405-M409 WeakPolarHBondContact O-CB 3.08Å; Y405-M409 VanDerWaalsContact O-CG 3.23Å; Y405-M409 WeakPolarHBondContact O-CG 3.4Å; Y405-M409 PolarHBondContact O-N 2.81Å; Y405-S480 PolarHBondContact OH-OG 3.18Å; Y405-Y481 HydrophobicContact CD1-CE1 4.48Å; Y405-Y481 AromaticContact CD2-CD1 3.71Å; Y405-Y481 HydrophobicContact CD2-CD1 3.71Å; Y405-Y481 AromaticContact CD2-CE1 3.53Å; Y405-Y481 HydrophobicContact CD2-CE1 3.53Å; Y405-Y481 AromaticContact CE2-CD1 3.75Å; Y405-Y481 HydrophobicContact CE2-CD1 3.75Å; Y405-Y481 AromaticContact CE2-CE1 3.64Å; Y405-Y481 HydrophobicContact CE2-CE1 3.64Å; Y405-Y481 HydrophobicContact CE2-CG 4.32Å; Y405-Y481 AromaticContact CG-CE1 3.98Å; Y405-Y481 HydrophobicContact CG-CE1 3.98Å; Y405-F484 VanDerWaalsContact CA-CE2 3.41Å; Y405-F484 HydrophobicContact CD2-CB 3.65Å; Y405-F484 AromaticContact CD2-CD1 3.91Å; Y405-F484 HydrophobicContact CD2-CD1 3.91Å; Y405-F484 HydrophobicContact CD2-CD2 4.06Å; Y405-F484 AromaticContact CD2-CG 3.6Å; Y405-F484 HydrophobicContact CD2-CG 3.6Å; Y405-F484 HydrophobicContact CE2-CB 3.9Å; Y405-F484 HydrophobicContact CE2-CG 4.36Å; Y405-F484 HydrophobicContact CG-CG 4.48Å
406R93.3Very high91.3Very high135 Ų13557 Ų5751%0.50927%0.268SS..Hα-helixtrans-59.8-46.7178.7-73.2-175.4-69.7150.7-11.3111.8L36 E402 D403 S404 I408 D410L36-R406 HydrophobicContact CD1-CG 4Å; E402-R406 WeakPolarHBondContact O-CG 3.46Å; E402-R406 PolarHBondContact O-N 3.42Å; E402-R406 PolarHBondContact O-NE 3.28Å; D403-R406 PolarHBondContact O-N 2.88Å; D403-R406 IonicContact OD1-CZ 3.88Å; D403-R406 IonicContact OD1-NH2 3.32Å; D403-R406 PolarHBondContact OD1-NH2 2.82Å; S404-R406 PolarHBondContact O-N 2.86Å; R406-I408 PolarHBondContact O-N 2.93Å; R406-D410 VanDerWaalsContact O-CB 3.27Å; R406-D410 WeakPolarHBondContact O-CB 3.08Å; R406-D410 PolarHBondContact O-N 3.04Å
407H94.5Very high91.5Very high56 Ų5656.5 Ų56.526%0.25926%0.263SS..Hα-helixtrans-66-36.1-177.8-85.9-50.5000114M393 V394 D403 S404 Y405 K411M393-H407 HydrophobicContact CB-CB 4.49Å; M393-H407 HydrophobicContact CG-CB 4.19Å; M393-H407 HydrophobicContact SD-CB 3.98Å; V394-H407 PolarHBondContact N-NE2 3.24Å; V394-H407 PolarHBondContact O-NE2 2.91Å; D403-H407 WeakPolarHBondContact O-CB 3.04Å; D403-H407 PolarHBondContact O-CD2 2.95Å; D403-H407 VanDerWaalsContact O-CD2 3.27Å; D403-H407 PolarHBondContact O-N 2.83Å; S404-H407 PolarHBondContact O-N 3.2Å; Y405-H407 PolarHBondContact O-N 3.48Å; H407-K411 WeakPolarHBondContact O-CD 3.16Å; H407-K411 WeakPolarHBondContact O-CG 3.32Å; H407-K411 PolarHBondContact O-NZ 2.74Å; H407-K411 VanDerWaalsContact O-NZ 3.14Å
408I95.5Very high91.7Very high0 Ų052.7 Ų52.70%025%0.25CS..Hα-helixtrans-81.5-47.2-176.3-75.3162.2000110M393 S404 Y405 R406 D410 K411 L416 W439 F484 R487 I488 M491M393-I408 HydrophobicContact CE-CG1 3.99Å; M393-I408 HydrophobicContact SD-CG1 4.22Å; S404-I408 WeakPolarHBondContact O-CB 3.07Å; S404-I408 WeakPolarHBondContact O-CG1 3.22Å; S404-I408 PolarHBondContact O-N 3.15Å; Y405-I408 PolarHBondContact O-N 2.78Å; R406-I408 PolarHBondContact O-N 2.93Å; I408-D410 PolarHBondContact O-N 3.48Å; I408-K411 PolarHBondContact O-N 2.8Å; I408-L416 HydrophobicContact CG1-CD2 4.39Å; I408-L416 HydrophobicContact CG2-CD1 4.23Å; I408-W439 HydrophobicContact CD1-CH2 3.78Å; I408-W439 HydrophobicContact CD1-CZ2 3.87Å; I408-F484 HydrophobicContact CB-CD2 4.01Å; I408-F484 HydrophobicContact CB-CE2 3.97Å; I408-F484 HydrophobicContact CD1-CD2 4.3Å; I408-F484 HydrophobicContact CD1-CE2 3.55Å; I408-F484 HydrophobicContact CD1-CZ 4.45Å; I408-F484 HydrophobicContact CG1-CE2 4.34Å; I408-F484 HydrophobicContact CG2-CD2 3.95Å; I408-F484 HydrophobicContact CG2-CE2 4.29Å; I408-R487 HydrophobicContact CG2-CB 3.99Å; I408-R487 PolarHBondContact O-NH1 3.5Å; I408-I488 HydrophobicContact CD1-CD1 3.13Å; I408-I488 HydrophobicContact CD1-CG1 4.08Å; I408-M491 HydrophobicContact CD1-SD 4.11Å; I408-M491 HydrophobicContact CG1-SD 4.21Å
409M94.4Very high91.9Very high60 Ų6051.6 Ų51.630%0.29624%0.239SC..Hα-helixtrans-63.7-27.8-178.5-65.9-59.1-69.500112.9Y405 F484Y405-M409 HydrophobicContact CD1-CG 4.48Å; Y405-M409 HydrophobicContact CD2-CG 3.98Å; Y405-M409 HydrophobicContact CE1-CG 4.31Å; Y405-M409 HydrophobicContact CE2-CG 3.78Å; Y405-M409 HydrophobicContact CG-CG 4.33Å; Y405-M409 VanDerWaalsContact O-CB 3.27Å; Y405-M409 WeakPolarHBondContact O-CB 3.08Å; Y405-M409 VanDerWaalsContact O-CG 3.23Å; Y405-M409 WeakPolarHBondContact O-CG 3.4Å; Y405-M409 PolarHBondContact O-N 2.81Å; M409-F484 HydrophobicContact CG-CB 4.31Å; M409-F484 HydrophobicContact SD-CB 3.93Å
410D94Very high92.1Very high140 Ų14049.5 Ų49.575%0.74923%0.226SC*.Hα-helixtrans-76.9-26.3173.9-173.264.7000113.6R406 I408R406-D410 VanDerWaalsContact O-CB 3.27Å; R406-D410 WeakPolarHBondContact O-CB 3.08Å; R406-D410 PolarHBondContact O-N 3.04Å; I408-D410 PolarHBondContact O-N 3.48Å
411K94.1Very high92Very high34 Ų3454.1 Ų54.115%0.14824%0.243CC..SBendtrans-85.1144.9-176.1-77.8178.6-175.468.60112.6C391 D392 M393 H407 I408 D415 L416 R487C391-K411 WeakPolarHBondContact SG-CD 3.41Å; C391-K411 WeakPolarHBondContact SG-CE 3.46Å; D392-K411 WeakPolarHBondContact O-CE 3.38Å; D392-K411 PolarHBondContact O-NZ 2.78Å; M393-K411 HydrophobicContact CE-CD 4.01Å; H407-K411 WeakPolarHBondContact O-CD 3.16Å; H407-K411 WeakPolarHBondContact O-CG 3.32Å; H407-K411 PolarHBondContact O-NZ 2.74Å; H407-K411 VanDerWaalsContact O-NZ 3.14Å; I408-K411 PolarHBondContact O-N 2.8Å; K411-D415 HydrophobicContact CB-CB 4.39Å; K411-L416 HydrophobicContact CB-CD2 3.82Å; K411-L416 HydrophobicContact CB-CG 4.11Å; K411-L416 HydrophobicContact CD-CD2 3.8Å; K411-L416 HydrophobicContact CG-CD2 4.48Å; K411-R487 PolarHBondContact O-NH1 2.74Å; K411-R487 VanDerWaalsContact O-NH1 3.11Å; K411-R487 PolarHBondContact O-NH2 2.62Å
412K91.8Very high92Very high127 Ų12754.1 Ų54.155%0.55224%0.243SC*.  trans-81.7160.2173.5-62.4179.9-174.8171.60111.1Y414 D415 L416K412-Y414 HydrophobicContact CB-CD1 3.92Å; K412-Y414 HydrophobicContact CB-CE1 3.62Å; K412-Y414 HydrophobicContact CD-CD1 4.43Å; K412-Y414 HydrophobicContact CD-CE1 3.42Å; K412-Y414 VanDerWaalsContact CD-CE1 3.42Å; K412-Y414 WeakPolarHBondContact CD-OH 3.14Å; K412-Y414 HydrophobicContact CG-CE1 4.18Å; K412-Y414 PolarHBondContact O-N 2.86Å; K412-D415 WeakPolarHBondContact O-CB 3.48Å; K412-D415 PolarHBondContact O-N 2.86Å; K412-L416 PolarHBondContact O-N 3.46Å
413D91.3Very high92.1Very high102 Ų10257.3 Ų57.355%0.54526%0.258SS..Hα-helixtrans-61.3-31.7-174.9-59.3-19.6000113.7D415 R417 R487D413-D415 VanDerWaalsContact C-N 3.33Å; D413-R417 WeakPolarHBondContact O-CG 3.44Å; D413-R417 PolarHBondContact O-N 2.83Å; D413-R417 PolarHBondContact O-NH1 2.82Å; D413-R487 IonicContact OD1-CZ 3.86Å; D413-R487 IonicContact OD1-NE 3.44Å; D413-R487 IonicContact OD1-NH2 3.55Å; D413-R487 PolarHBondContact OD1-NH2 2.85Å
414Y89.7Confident91.8Very high86 Ų8657.3 Ų57.334%0.33726%0.258SS..Hα-helixtrans-73-26.917767.7-100.2000112.8K412 R417K412-Y414 HydrophobicContact CB-CD1 3.92Å; K412-Y414 HydrophobicContact CB-CE1 3.62Å; K412-Y414 HydrophobicContact CD-CD1 4.43Å; K412-Y414 HydrophobicContact CD-CE1 3.42Å; K412-Y414 VanDerWaalsContact CD-CE1 3.42Å; K412-Y414 WeakPolarHBondContact CD-OH 3.14Å; K412-Y414 HydrophobicContact CG-CE1 4.18Å; K412-Y414 PolarHBondContact O-N 2.86Å; Y414-R417 VanDerWaalsContact CA-CZ 3.5Å; Y414-R417 VanDerWaalsContact CB-NH2 3.3Å
415D91.4Very high91.4Very high46 Ų4663.4 Ų63.425%0.24629%0.285CS..Hα-helixtrans-72.1-42.7176.1-64.1-50.5000110.1C391 K411 K412 D413 R417 N418C391-D415 WeakPolarHBondContact CB-O 3.34Å; K411-D415 HydrophobicContact CB-CB 4.39Å; K412-D415 WeakPolarHBondContact O-CB 3.48Å; K412-D415 PolarHBondContact O-N 2.86Å; D413-D415 VanDerWaalsContact C-N 3.33Å; D415-R417 PolarHBondContact O-N 2.89Å; D415-R417 VanDerWaalsContact O-N 3.17Å; D415-N418 VanDerWaalsContact O-CB 3.25Å; D415-N418 WeakPolarHBondContact O-CB 3.37Å; D415-N418 PolarHBondContact O-N 2.77Å; D415-N418 PolarHBondContact O-ND2 3.02Å
416L93.4Very high90.9Very high11 Ų1165.8 Ų65.86%0.05832%0.316CS..Hα-helixtrans-65.8-17.1177.9-61.9-179.7000113.8M393 I408 K411 K412 R487 M491 H495M393-L416 HydrophobicContact CE-CD2 3.72Å; I408-L416 HydrophobicContact CG1-CD2 4.39Å; I408-L416 HydrophobicContact CG2-CD1 4.23Å; K411-L416 HydrophobicContact CB-CD2 3.82Å; K411-L416 HydrophobicContact CB-CG 4.11Å; K411-L416 HydrophobicContact CD-CD2 3.8Å; K411-L416 HydrophobicContact CG-CD2 4.48Å; K412-L416 PolarHBondContact O-N 3.46Å; L416-R487 VanDerWaalsContact CD1-CZ 3.46Å; L416-M491 HydrophobicContact CB-CG 4.31Å; L416-M491 HydrophobicContact CB-SD 4.32Å; L416-M491 HydrophobicContact CD1-CG 4.4Å; L416-M491 HydrophobicContact CD1-SD 3.9Å; L416-M491 HydrophobicContact CD2-CE 4.06Å; L416-M491 HydrophobicContact CD2-SD 3.9Å; L416-M491 HydrophobicContact CG-SD 4.27Å; L416-H495 PolarHBondContact O-NE2 2.68Å
417R92Very high90.3Very high61 Ų6163.1 Ų63.123%0.2331%0.309CS..THydrogen-bonded Turntrans-80.9-16.2173.9-76-168.9-64.6-92.210.5113.7D413 Y414 D415 Y494D413-R417 WeakPolarHBondContact O-CG 3.44Å; D413-R417 PolarHBondContact O-N 2.83Å; D413-R417 PolarHBondContact O-NH1 2.82Å; Y414-R417 VanDerWaalsContact CA-CZ 3.5Å; Y414-R417 VanDerWaalsContact CB-NH2 3.3Å; D415-R417 PolarHBondContact O-N 2.89Å; D415-R417 VanDerWaalsContact O-N 3.17Å; R417-Y494 HydrophobicContact CB-CE1 3.94Å; R417-Y494 HydrophobicContact CB-CE2 4.36Å; R417-Y494 WeakPolarHBondContact CB-OH 3.36Å; R417-Y494 HydrophobicContact CG-CD2 4.27Å; R417-Y494 HydrophobicContact CG-CE1 4.01Å; R417-Y494 HydrophobicContact CG-CE2 3.72Å; R417-Y494 WeakPolarHBondContact O-CE1 3.22Å; R417-Y494 PolarHBondContact O-OH 3.3Å
418N91.1Very high89.1Confident12 Ų1268 Ų686%0.06434%0.343CS..SBendtrans-70.7167.1176.5-68.3-34.2000111.1G389 C391 D415 L420 H495G389-N418 WeakPolarHBondContact O-CB 3.4Å; C391-N418 HydrophobicContact CB-CB 4.28Å; D415-N418 VanDerWaalsContact O-CB 3.25Å; D415-N418 WeakPolarHBondContact O-CB 3.37Å; D415-N418 PolarHBondContact O-N 2.77Å; D415-N418 PolarHBondContact O-ND2 3.02Å; N418-L420 PolarHBondContact O-N 2.86Å; N418-L420 VanDerWaalsContact O-N 3.15Å; N418-H495 PolarHBondContact O-CE1 3.45Å; N418-H495 VanDerWaalsContact O-CE1 3.23Å
419K88.7Confident87.3Confident102 Ų10269.7 Ų69.744%0.44336%0.361SS..EExtended strand (participates in β ladder)trans-60121.9176.8-176.2174.8-179.4175.20109.3G389 K390 C391G389-K419 PolarHBondContact O-N 2.82Å; K390-K419 WeakPolarHBondContact CA-O 3.27Å; C391-K419 PolarHBondContact N-O 2.83Å
420L90.8Very high85.6Confident7 Ų772.6 Ų72.64%0.03738%0.377CS..EExtended strand (participates in β ladder)trans-68.7136.6177.3-54.5-176.9000109.8C391 N418 I422 T436 F440 M491C391-L420 HydrophobicContact CB-CD2 3.92Å; N418-L420 PolarHBondContact O-N 2.86Å; N418-L420 VanDerWaalsContact O-N 3.15Å; L420-I422 HydrophobicContact CB-CD1 4.47Å; L420-T436 HydrophobicContact CB-CG2 4.22Å; L420-T436 HydrophobicContact CD1-CG2 3.96Å; L420-F440 HydrophobicContact CD1-CE2 3.84Å; L420-F440 HydrophobicContact CD1-CZ 4.15Å; L420-M491 HydrophobicContact CD1-CE 3.94Å; L420-M491 HydrophobicContact CD2-CE 3.91Å
421W88.3Confident84Confident105 Ų10566.2 Ų66.240%0.39834%0.343SS..EExtended strand (participates in β ladder)trans-127.696.1174.5-105.156000107C391 D392 M393C391-W421 PolarHBondContact O-N 3.11Å; D392-W421 CarbonylContact C-O 3.22Å; D392-W421 WeakPolarHBondContact CA-O 3.5Å; D392-W421 WeakPolarHBondContact OD1-CB 3.48Å; M393-W421 PolarHBondContact N-O 3.01Å
422I90.1Very high82.6Confident2 Ų270.3 Ų70.31%0.0136%0.358CS..EExtended strand (participates in β ladder)trans-100.3131.3-178.6-49.8-57.9000109.6M393 V395 L420 D431 V435 W439M393-I422 HydrophobicContact CB-CD1 3.78Å; M393-I422 HydrophobicContact CG-CD1 3.97Å; M393-I422 WeakPolarHBondContact O-CA 3.49Å; M393-I422 HydrophobicContact SD-CD1 4.01Å; V395-I422 HydrophobicContact CG2-CG2 4.19Å; L420-I422 HydrophobicContact CB-CD1 4.47Å; I422-D431 PolarHBondContact N-OD2 3.27Å; I422-D431 WeakPolarHBondContact O-CB 3.34Å; I422-V435 HydrophobicContact CB-CG1 4.15Å; I422-V435 HydrophobicContact CG2-CG1 4.15Å; I422-V435 VanDerWaalsContact O-CG1 3.27Å; I422-V435 WeakPolarHBondContact O-CG1 3.43Å; I422-W439 HydrophobicContact CB-CB 4.48Å; I422-W439 HydrophobicContact CD1-CD2 4.25Å; I422-W439 HydrophobicContact CD1-CE3 4.38Å; I422-W439 HydrophobicContact CG1-CB 4.39Å; I422-W439 HydrophobicContact CG1-CD2 4.29Å; I422-W439 HydrophobicContact CG1-CE3 4.39Å; I422-W439 HydrophobicContact CG1-CG 4.29Å; I422-W439 HydrophobicContact CG2-CB 3.82Å; I422-W439 HydrophobicContact CG2-CD2 4.5Å; I422-W439 HydrophobicContact CG2-CG 3.77Å
423E88.1Confident81.5Confident89 Ų8964.6 Ų64.642%0.41634%0.335SS..EExtended strand (participates in β ladder)trans-126128.4176-175.9179.7157.700109.5M393 V394 V395M393-E423 PolarHBondContact O-N 2.87Å; V394-E423 CarbonylContact C-O 3.57Å; V394-E423 WeakPolarHBondContact CA-O 3.23Å; V394-E423 HydrophobicContact CG2-CB 4.28Å; V395-E423 PolarHBondContact N-O 2.86Å
424F88.4Confident80.7Confident5 Ų559.7 Ų59.72%0.02231%0.309CS..EExtended strand (participates in β ladder)trans-82.7123.4167-72.5-71.6000109.1V395 R397 L400 G426 E427 V435 E438 W439 L442V395-F424 HydrophobicContact CG2-CD1 3.79Å; V395-F424 HydrophobicContact CG2-CE1 3.81Å; V395-F424 CarbonylContact O-C 3.58Å; V395-F424 VanDerWaalsContact O-CA 3.27Å; V395-F424 WeakPolarHBondContact O-CA 3.46Å; R397-F424 HydrophobicContact CG-CD1 3.71Å; R397-F424 HydrophobicContact CG-CE1 4.09Å; R397-F424 HydrophobicContact CG-CG 4.35Å; L400-F424 HydrophobicContact CD1-CE1 3.99Å; F424-G426 PolarHBondContact O-N 2.81Å; F424-E427 HydrophobicContact CB-CB 4.11Å; F424-E427 VanDerWaalsContact CB-CD 3.5Å; F424-E427 HydrophobicContact CB-CG 4.18Å; F424-E427 WeakPolarHBondContact CB-OE1 3.34Å; F424-E427 WeakPolarHBondContact O-CB 3.21Å; F424-E427 PolarHBondContact O-N 2.77Å; F424-V435 HydrophobicContact CD2-CG1 3.67Å; F424-V435 HydrophobicContact CE2-CG1 3.69Å; F424-E438 HydrophobicContact CE2-CG 4.34Å; F424-W439 HydrophobicContact CZ-CB 4.38Å; F424-L442 HydrophobicContact CE1-CD1 4.3Å; F424-L442 HydrophobicContact CZ-CD1 3.85Å
425F86.1Confident80.4Confident128 Ų12856.6 Ų56.656%0.56130%0.299SS*.THydrogen-bonded Turntrans-56.4127.2-175.1179.8-92.3000111.6V394 V395 H396 E427V394-F425 HydrophobicContact CG1-CB 4.22Å; V394-F425 HydrophobicContact CG1-CD2 4.29Å; V395-F425 PolarHBondContact O-N 3.15Å; H396-F425 VanDerWaalsContact CD2-CB 3.5Å; H396-F425 WeakPolarHBondContact CD2-CB 3.38Å; H396-F425 AromaticContact CD2-CD1 3.48Å; H396-F425 VanDerWaalsContact CD2-CD1 3.48Å; H396-F425 WeakPolarHBondContact CD2-CD1 3.32Å; H396-F425 AromaticContact CD2-CG 3.56Å; H396-F425 AromaticContact CE1-CG 3.91Å; H396-F425 AromaticContact NE2-CD1 3.34Å; H396-F425 VanDerWaalsContact NE2-CD1 3.34Å; H396-F425 WeakPolarHBondContact NE2-CD1 3.47Å; H396-F425 AromaticContact NE2-CD2 3.71Å; H396-F425 AromaticContact NE2-CE1 3.93Å; H396-F425 AromaticContact NE2-CG 3.21Å; H396-F425 WeakPolarHBondContact NE2-CG 3.37Å; F425-E427 VanDerWaalsContact C-N 3.28Å; F425-E427 PolarHBondContact O-N 3.3Å
426G82.2Confident80.3Confident74 Ų7454.7 Ų54.776%0.76329%0.289SS*.THydrogen-bonded Turntrans84-5.4-179.600000114.7F424F424-G426 PolarHBondContact O-N 2.81Å
427E80.8Confident79.8Confident78 Ų7855 Ų5536%0.36429%0.29SS..SBendtrans-100.1141.1180-67.5172.9-13600112.1R397 F424 F425 G429R397-E427 WeakPolarHBondContact CD-OE1 3.29Å; R397-E427 IonicContact CZ-OE1 4Å; R397-E427 IonicContact CZ-OE2 2.73Å; R397-E427 IonicContact NE-OE1 2.75Å; R397-E427 PolarHBondContact NE-OE1 3.01Å; R397-E427 IonicContact NE-OE2 3.42Å; R397-E427 PolarHBondContact NE-OE2 2.99Å; R397-E427 IonicContact NH2-OE1 3.15Å; R397-E427 IonicContact NH2-OE2 3.38Å; R397-E427 PolarHBondContact NH2-OE2 3.35Å; F424-E427 HydrophobicContact CB-CB 4.11Å; F424-E427 VanDerWaalsContact CB-CD 3.5Å; F424-E427 HydrophobicContact CB-CG 4.18Å; F424-E427 WeakPolarHBondContact CB-OE1 3.34Å; F424-E427 WeakPolarHBondContact O-CB 3.21Å; F424-E427 PolarHBondContact O-N 2.77Å; F425-E427 VanDerWaalsContact C-N 3.28Å; F425-E427 PolarHBondContact O-N 3.3Å; E427-G429 VanDerWaalsContact C-N 3.32Å; E427-G429 PolarHBondContact O-N 3.38Å
428T68.2Low79.4Confident158 Ų15854.7 Ų54.797%0.96929%0.291SS*.  trans-82.376.5175.345.90000110.7
429G58.8Low79.4Confident36 Ų3654.1 Ų54.137%0.37129%0.288SS..  trans-110.2114.417700000112.8E427E427-G429 VanDerWaalsContact C-N 3.32Å; E427-G429 PolarHBondContact O-N 3.38Å
430L59.4Low79.6Confident121 Ų12149.3 Ų49.363%0.63427%0.267SS*.  trans-85.6106.6162.7-74168.9000108.1Y432L430-Y432 VanDerWaalsContact C-N 3.28Å; L430-Y432 HydrophobicContact CB-CD2 4.05Å; L430-Y432 HydrophobicContact CB-CE2 3.78Å; L430-Y432 HydrophobicContact CD1-CE2 4.2Å; L430-Y432 PolarHBondContact O-N 2.76Å
431D60Low79.4Confident6 Ų649.8 Ų49.83%0.03227%0.269CS..  trans-73.182.8-177.9-165.515000111.8I422 G433 V435 T436I422-D431 PolarHBondContact N-OD2 3.27Å; I422-D431 WeakPolarHBondContact O-CB 3.34Å; D431-G433 PolarHBondContact O-N 3.04Å; D431-G433 WeakPolarHBondContact OD1-CA 3.44Å; D431-G433 PolarHBondContact OD1-N 3.29Å; D431-V435 HydrophobicContact CB-CB 4.19Å; D431-V435 HydrophobicContact CB-CG2 4.41Å; D431-V435 PolarHBondContact OD1-N 3.27Å; D431-T436 PolarHBondContact OD1-N 3.17Å; D431-T436 PolarHBondContact OD2-OG1 2.81Å
432Y65.1Low79.4Confident120 Ų12047 Ų4747%0.47126%0.261SS..SBendtrans-73.6-9.3162.3-70.9-77.2000111.1L430 S668L430-Y432 VanDerWaalsContact C-N 3.28Å; L430-Y432 HydrophobicContact CB-CD2 4.05Å; L430-Y432 HydrophobicContact CB-CE2 3.78Å; L430-Y432 HydrophobicContact CD1-CE2 4.2Å; L430-Y432 PolarHBondContact O-N 2.76Å; Y432-S668 VanDerWaalsContact C-CB 3.49Å; Y432-S668 CarbonylContact O-C 3.58Å; Y432-S668 WeakPolarHBondContact O-CA 3.35Å; Y432-S668 WeakPolarHBondContact O-CB 3.4Å
433G68.3Low79.4Confident7 Ų746.9 Ų46.97%0.07226%0.261CS..SBendtrans126.4-3.4179.100000114.1D431 R437D431-G433 PolarHBondContact O-N 3.04Å; D431-G433 WeakPolarHBondContact OD1-CA 3.44Å; D431-G433 PolarHBondContact OD1-N 3.29Å; G433-R437 PolarHBondContact O-N 2.73Å; G433-R437 PolarHBondContact O-NE 3.16Å
434G74.5Confident79.3Confident0 Ų042.6 Ų42.60%024%0.241CC..Hα-helixtrans-71.6-49.7169.400000111.5T436 R437 E438 C691G434-T436 VanDerWaalsContact C-N 3.34Å; G434-T436 PolarHBondContact O-N 3.14Å; G434-R437 WeakPolarHBondContact O-CB 3.22Å; G434-R437 PolarHBondContact O-N 2.76Å; G434-E438 PolarHBondContact O-N 3.41Å; G434-C691 PolarHBondContact N-SG 3.39Å; G434-C691 VanDerWaalsContact N-SG 3.35Å
435V84Confident79Confident20 Ų2046.6 Ų46.612%0.12126%0.259CS..Hα-helixtrans-61.8-42.7178.6-172.40000110.6I422 F424 D431 R437 E438 W439I422-V435 HydrophobicContact CB-CG1 4.15Å; I422-V435 HydrophobicContact CG2-CG1 4.15Å; I422-V435 VanDerWaalsContact O-CG1 3.27Å; I422-V435 WeakPolarHBondContact O-CG1 3.43Å; F424-V435 HydrophobicContact CD2-CG1 3.67Å; F424-V435 HydrophobicContact CE2-CG1 3.69Å; D431-V435 HydrophobicContact CB-CB 4.19Å; D431-V435 HydrophobicContact CB-CG2 4.41Å; D431-V435 PolarHBondContact OD1-N 3.27Å; V435-R437 VanDerWaalsContact C-N 3.27Å; V435-R437 PolarHBondContact O-N 3.21Å; V435-E438 PolarHBondContact O-N 2.89Å; V435-W439 VanDerWaalsContact O-CB 3.32Å; V435-W439 WeakPolarHBondContact O-CB 3.33Å; V435-W439 PolarHBondContact O-N 2.76Å
436T88.5Confident78.8Confident6 Ų643.1 Ų43.14%0.03725%0.245CC..Hα-helixtrans-54.5-40.6172.1-68.90000112.7L420 D431 G434 F440L420-T436 HydrophobicContact CB-CG2 4.22Å; L420-T436 HydrophobicContact CD1-CG2 3.96Å; D431-T436 PolarHBondContact OD1-N 3.17Å; D431-T436 PolarHBondContact OD2-OG1 2.81Å; G434-T436 VanDerWaalsContact C-N 3.34Å; G434-T436 PolarHBondContact O-N 3.14Å; T436-F440 HydrophobicContact CG2-CD2 3.98Å; T436-F440 HydrophobicContact CG2-CE2 3.91Å; T436-F440 VanDerWaalsContact O-CD2 3.26Å; T436-F440 WeakPolarHBondContact O-CD2 3.43Å; T436-F440 PolarHBondContact O-N 2.8Å; T436-F440 VanDerWaalsContact O-N 3.15Å
437R82.6Confident78.7Confident18 Ų1839.7 Ų39.77%0.06821%0.209CC..Hα-helixtrans-70.9-45.8-179.4-87-177.4-68.9172.3-0.8112.3G433 G434 V435 W439 F440 F441 K497 S652 Y666 T690 N693G433-R437 PolarHBondContact O-N 2.73Å; G433-R437 PolarHBondContact O-NE 3.16Å; G434-R437 WeakPolarHBondContact O-CB 3.22Å; G434-R437 PolarHBondContact O-N 2.76Å; V435-R437 VanDerWaalsContact C-N 3.27Å; V435-R437 PolarHBondContact O-N 3.21Å; R437-W439 PolarHBondContact O-N 3.2Å; R437-F440 PolarHBondContact O-N 2.93Å; R437-F441 WeakPolarHBondContact O-CB 3.42Å; R437-F441 PolarHBondContact O-N 3.45Å; R437-K497 HydrophobicContact CG-CD 3.86Å; R437-S652 PolarHBondContact NE-O 3.01Å; R437-S652 PolarHBondContact NH1-O 2.97Å; R437-Y666 PolarHBondContact NH1-O 2.83Å; R437-T690 PolarHBondContact NH2-O 3.26Å; R437-N693 PolarHBondContact NH1-OD1 3.07Å; R437-N693 PolarHBondContact NH2-OD1 3.26Å
438E84.8Confident78.3Confident55 Ų5536.6 Ų36.626%0.25719%0.194SC..Hα-helixtrans-57.9-42.5174.5-176-176.7176.300110.5R397 F424 G434 V435 F440 F441 L442R397-E438 IonicContact CZ-OE1 3.01Å; R397-E438 IonicContact NH1-OE1 3.26Å; R397-E438 PolarHBondContact NH1-OE1 3.19Å; R397-E438 IonicContact NH2-OE1 2.79Å; R397-E438 PolarHBondContact NH2-OE1 3.01Å; R397-E438 IonicContact NH2-OE2 3.35Å; F424-E438 HydrophobicContact CE2-CG 4.34Å; G434-E438 PolarHBondContact O-N 3.41Å; V435-E438 PolarHBondContact O-N 2.89Å; E438-F440 PolarHBondContact O-N 3.15Å; E438-F441 WeakPolarHBondContact O-CB 3.45Å; E438-F441 PolarHBondContact O-N 2.95Å; E438-L442 HydrophobicContact CG-CD1 3.84Å; E438-L442 HydrophobicContact CG-CG 4.14Å; E438-L442 WeakPolarHBondContact O-CB 3.21Å; E438-L442 WeakPolarHBondContact O-CG 3.44Å; E438-L442 PolarHBondContact O-N 3.37Å
439W90.8Very high78.3Confident0 Ų031 Ų310%016%0.158CC..Hα-helixtrans-58.8-46.9175.7174.480.1000112.9M393 S404 I408 I422 F424 V435 R437 F441 L443 I488 M491M393-W439 HydrophobicContact SD-CZ2 4.39Å; S404-W439 PolarHBondContact OG-NE1 3.44Å; I408-W439 HydrophobicContact CD1-CH2 3.78Å; I408-W439 HydrophobicContact CD1-CZ2 3.87Å; I422-W439 HydrophobicContact CB-CB 4.48Å; I422-W439 HydrophobicContact CD1-CD2 4.25Å; I422-W439 HydrophobicContact CD1-CE3 4.38Å; I422-W439 HydrophobicContact CG1-CB 4.39Å; I422-W439 HydrophobicContact CG1-CD2 4.29Å; I422-W439 HydrophobicContact CG1-CE3 4.39Å; I422-W439 HydrophobicContact CG1-CG 4.29Å; I422-W439 HydrophobicContact CG2-CB 3.82Å; I422-W439 HydrophobicContact CG2-CD2 4.5Å; I422-W439 HydrophobicContact CG2-CG 3.77Å; F424-W439 HydrophobicContact CZ-CB 4.38Å; V435-W439 VanDerWaalsContact O-CB 3.32Å; V435-W439 WeakPolarHBondContact O-CB 3.33Å; V435-W439 PolarHBondContact O-N 2.76Å; R437-W439 PolarHBondContact O-N 3.2Å; W439-F441 VanDerWaalsContact C-N 3.31Å; W439-F441 PolarHBondContact O-N 2.94Å; W439-L443 HydrophobicContact CH2-CD2 3.97Å; W439-L443 HydrophobicContact CZ2-CD2 3.54Å; W439-L443 WeakPolarHBondContact O-CB 3.45Å; W439-L443 PolarHBondContact O-N 3.23Å; W439-I488 HydrophobicContact CH2-CD1 3.48Å; W439-I488 VanDerWaalsContact CH2-CD1 3.48Å; W439-I488 HydrophobicContact CZ2-CD1 4.03Å; W439-I488 HydrophobicContact CZ3-CD1 4.33Å; W439-M491 HydrophobicContact CH2-CE 4.17Å; W439-M491 HydrophobicContact CZ3-CE 4.39Å
440F91.8Very high78.6Confident1 Ų132 Ų320%0.00416%0.158CC..Hα-helixtrans-61.2-40.4174.6-87.3-71.3000112.4L420 T436 R437 E438 S444 I488 M491 A492 K497 L499L420-F440 HydrophobicContact CD1-CE2 3.84Å; L420-F440 HydrophobicContact CD1-CZ 4.15Å; T436-F440 HydrophobicContact CG2-CD2 3.98Å; T436-F440 HydrophobicContact CG2-CE2 3.91Å; T436-F440 VanDerWaalsContact O-CD2 3.26Å; T436-F440 WeakPolarHBondContact O-CD2 3.43Å; T436-F440 PolarHBondContact O-N 2.8Å; T436-F440 VanDerWaalsContact O-N 3.15Å; R437-F440 PolarHBondContact O-N 2.93Å; E438-F440 PolarHBondContact O-N 3.15Å; F440-S444 WeakPolarHBondContact O-CB 3.43Å; F440-S444 PolarHBondContact O-N 2.77Å; F440-S444 PolarHBondContact O-OG 2.9Å; F440-I488 HydrophobicContact CD1-CG2 4.3Å; F440-I488 HydrophobicContact CE1-CG2 4.23Å; F440-M491 HydrophobicContact CE1-CB 4.24Å; F440-M491 HydrophobicContact CZ-CB 3.96Å; F440-A492 HydrophobicContact CD1-CB 4.15Å; F440-A492 HydrophobicContact CE1-CB 3.79Å; F440-A492 HydrophobicContact CZ-CB 4.39Å; F440-K497 HydrophobicContact CD2-CB 3.63Å; F440-K497 HydrophobicContact CD2-CG 3.58Å; F440-K497 HydrophobicContact CE2-CB 3.85Å; F440-K497 HydrophobicContact CE2-CG 3.52Å; F440-K497 HydrophobicContact CG-CB 4.03Å; F440-K497 HydrophobicContact CG-CG 4.46Å; F440-K497 HydrophobicContact CZ-CB 4.39Å; F440-K497 HydrophobicContact CZ-CG 4.33Å; F440-L499 HydrophobicContact CB-CD2 4.39Å; F440-L499 HydrophobicContact CD1-CD2 3.7Å; F440-L499 HydrophobicContact CE1-CD2 4.5Å; F440-L499 HydrophobicContact CG-CD2 4.48Å
441F86Confident78.8Confident17 Ų1734.1 Ų34.18%0.07516%0.159CC..Hα-helixtrans-65.6-49.4178.5171-88.4000112.2R437 E438 W439 L443 S444 H445 D500 Q649 S655R437-F441 WeakPolarHBondContact O-CB 3.42Å; R437-F441 PolarHBondContact O-N 3.45Å; E438-F441 WeakPolarHBondContact O-CB 3.45Å; E438-F441 PolarHBondContact O-N 2.95Å; W439-F441 VanDerWaalsContact C-N 3.31Å; W439-F441 PolarHBondContact O-N 2.94Å; F441-L443 VanDerWaalsContact C-N 3.33Å; F441-S444 PolarHBondContact O-N 3.43Å; F441-S444 PolarHBondContact O-OG 3.3Å; F441-H445 AromaticContact CD2-CE1 3.99Å; F441-H445 AromaticContact CE1-CE1 3.67Å; F441-H445 AromaticContact CE1-ND1 3.87Å; F441-H445 AromaticContact CE2-CE1 3.4Å; F441-H445 VanDerWaalsContact CE2-CE1 3.4Å; F441-H445 WeakPolarHBondContact CE2-CE1 3.4Å; F441-H445 AromaticContact CZ-CE1 3.2Å; F441-H445 WeakPolarHBondContact CZ-CE1 3.41Å; F441-H445 AromaticContact CZ-ND1 3.86Å; F441-H445 AromaticContact CZ-NE2 3.95Å; F441-H445 PolarHBondContact O-N 3.34Å; F441-H445 PolarHBondContact O-ND1 2.8Å; F441-D500 HydrophobicContact CD2-CB 3.89Å; F441-D500 HydrophobicContact CE2-CB 4.07Å; F441-D500 WeakPolarHBondContact CE2-OD2 3.47Å; F441-Q649 HydrophobicContact CE2-CG 4.38Å; F441-Q649 HydrophobicContact CZ-CG 4.27Å; F441-S655 WeakPolarHBondContact CE2-OG 3.18Å
442L88.8Confident79.3Confident45 Ų4535.1 Ų35.124%0.23616%0.163CC..Hα-helixtrans-67.8-38.2179.4-66.8176.4000111L400 F424 E438 H445 Q446L400-L442 HydrophobicContact CD2-CB 3.31Å; L400-L442 HydrophobicContact CD2-CD1 4.41Å; L400-L442 HydrophobicContact CD2-CG 4.49Å; F424-L442 HydrophobicContact CE1-CD1 4.3Å; F424-L442 HydrophobicContact CZ-CD1 3.85Å; E438-L442 HydrophobicContact CG-CD1 3.84Å; E438-L442 HydrophobicContact CG-CG 4.14Å; E438-L442 WeakPolarHBondContact O-CB 3.21Å; E438-L442 WeakPolarHBondContact O-CG 3.44Å; E438-L442 PolarHBondContact O-N 3.37Å; L442-H445 PolarHBondContact O-N 2.82Å; L442-Q446 PolarHBondContact O-N 3.42Å; L442-Q446 VanDerWaalsContact O-N 3.15Å
443L89.9Confident79.6Confident0 Ų029.8 Ų29.80%015%0.145CC..Hα-helixtrans-69.1-35.5178.3-174.661.9000111.6L400 F401 W439 F441 H445 Q446 I447 F484 I488L400-L443 HydrophobicContact CD2-CB 4.49Å; F401-L443 HydrophobicContact CB-CD1 4.45Å; F401-L443 HydrophobicContact CD2-CD1 3.87Å; W439-L443 HydrophobicContact CH2-CD2 3.97Å; W439-L443 HydrophobicContact CZ2-CD2 3.54Å; W439-L443 WeakPolarHBondContact O-CB 3.45Å; W439-L443 PolarHBondContact O-N 3.23Å; F441-L443 VanDerWaalsContact C-N 3.33Å; L443-H445 VanDerWaalsContact C-N 3.33Å; L443-H445 PolarHBondContact O-N 3.48Å; L443-Q446 PolarHBondContact O-N 2.99Å; L443-I447 HydrophobicContact CD1-CG1 4.35Å; L443-I447 HydrophobicContact CD2-CD1 4.4Å; L443-I447 HydrophobicContact CG-CD1 3.86Å; L443-I447 HydrophobicContact CG-CG1 4.19Å; L443-I447 WeakPolarHBondContact O-CB 3.46Å; L443-I447 VanDerWaalsContact O-CG1 3.23Å; L443-I447 WeakPolarHBondContact O-CG1 3.39Å; L443-I447 PolarHBondContact O-N 3.18Å; L443-F484 HydrophobicContact CD1-CZ 4.26Å; L443-F484 HydrophobicContact CD2-CZ 4.1Å; L443-I488 HydrophobicContact CD2-CD1 3.38Å; L443-I488 HydrophobicContact CD2-CG1 3.9Å; L443-I488 HydrophobicContact CD2-CG2 4.47Å
444S86Confident80.2Confident0 Ų029.5 Ų29.50%014%0.141CC..Hα-helixtrans-60.3-45.3173.365.20000110.6F440 F441 Q446 I447 F448 D500F440-S444 WeakPolarHBondContact O-CB 3.43Å; F440-S444 PolarHBondContact O-N 2.77Å; F440-S444 PolarHBondContact O-OG 2.9Å; F441-S444 PolarHBondContact O-N 3.43Å; F441-S444 PolarHBondContact O-OG 3.3Å; S444-Q446 VanDerWaalsContact C-N 3.29Å; S444-Q446 PolarHBondContact O-N 3.41Å; S444-I447 PolarHBondContact O-N 3.24Å; S444-F448 WeakPolarHBondContact O-CD2 2.75Å; S444-F448 PolarHBondContact O-N 2.82Å; S444-D500 WeakPolarHBondContact OG-CA 3.42Å; S444-D500 WeakPolarHBondContact OG-CB 3.14Å; S444-D500 PolarHBondContact OG-N 3.08Å; S444-D500 PolarHBondContact OG-O 3.07Å
445H82Confident80.5Confident88 Ų8829.9 Ų29.941%0.40714%0.143SC..Hα-helixtrans-57.5-39.6175.4-74.377.9000113.2F441 L442 L443 N449 D500F441-H445 AromaticContact CD2-CE1 3.99Å; F441-H445 AromaticContact CE1-CE1 3.67Å; F441-H445 AromaticContact CE1-ND1 3.87Å; F441-H445 AromaticContact CE2-CE1 3.4Å; F441-H445 VanDerWaalsContact CE2-CE1 3.4Å; F441-H445 WeakPolarHBondContact CE2-CE1 3.4Å; F441-H445 AromaticContact CZ-CE1 3.2Å; F441-H445 WeakPolarHBondContact CZ-CE1 3.41Å; F441-H445 AromaticContact CZ-ND1 3.86Å; F441-H445 AromaticContact CZ-NE2 3.95Å; F441-H445 PolarHBondContact O-N 3.34Å; F441-H445 PolarHBondContact O-ND1 2.8Å; L442-H445 PolarHBondContact O-N 2.82Å; L443-H445 VanDerWaalsContact C-N 3.33Å; L443-H445 PolarHBondContact O-N 3.48Å; H445-N449 PolarHBondContact O-N 3.17Å; H445-D500 IonicContact CE1-OD2 3.1Å; H445-D500 PolarHBondContact CE1-OD2 2.9Å; H445-D500 VanDerWaalsContact CE1-OD2 3.23Å; H445-D500 IonicContact NE2-OD2 3.56Å
446Q82Confident79.8Confident56 Ų5632.1 Ų32.126%0.26215%0.152SC..Hα-helixtrans-70.4-45.5175.7-66.1-60.9-4400112.1L400 F401 L442 L443 S444 F448 N449 Y452L400-Q446 HydrophobicContact CD2-CG 4.39Å; F401-Q446 HydrophobicContact CB-CB 3.99Å; F401-Q446 HydrophobicContact CB-CG 4.43Å; F401-Q446 HydrophobicContact CD2-CB 3.83Å; F401-Q446 HydrophobicContact CG-CB 4.3Å; L442-Q446 PolarHBondContact O-N 3.42Å; L442-Q446 VanDerWaalsContact O-N 3.15Å; L443-Q446 PolarHBondContact O-N 2.99Å; S444-Q446 VanDerWaalsContact C-N 3.29Å; S444-Q446 PolarHBondContact O-N 3.41Å; Q446-F448 PolarHBondContact O-N 2.7Å; Q446-F448 VanDerWaalsContact O-N 3.11Å; Q446-N449 WeakPolarHBondContact O-CB 3.33Å; Q446-N449 PolarHBondContact O-N 2.75Å; Q446-Y452 HydrophobicContact CB-CE2 4.35Å; Q446-Y452 WeakPolarHBondContact O-CD2 3.31Å; Q446-Y452 WeakPolarHBondContact O-CE2 3.29Å
447I80.5Confident79Confident1 Ų137.1 Ų37.11%0.00517%0.171CC..Hα-helixtrans-52.4-38.2179.7-74.4165.4000111.9F401 L443 S444 F455 F484 I485 I488F401-I447 HydrophobicContact CD2-CG1 4.17Å; F401-I447 HydrophobicContact CE2-CB 4.3Å; F401-I447 HydrophobicContact CE2-CG1 3.68Å; L443-I447 HydrophobicContact CD1-CG1 4.35Å; L443-I447 HydrophobicContact CD2-CD1 4.4Å; L443-I447 HydrophobicContact CG-CD1 3.86Å; L443-I447 HydrophobicContact CG-CG1 4.19Å; L443-I447 WeakPolarHBondContact O-CB 3.46Å; L443-I447 VanDerWaalsContact O-CG1 3.23Å; L443-I447 WeakPolarHBondContact O-CG1 3.39Å; L443-I447 PolarHBondContact O-N 3.18Å; S444-I447 PolarHBondContact O-N 3.24Å; I447-F455 HydrophobicContact CG2-CE2 3.88Å; I447-F484 HydrophobicContact CG1-CE1 4.43Å; I447-I485 HydrophobicContact CB-CG1 4.45Å; I447-I485 HydrophobicContact CD1-CG1 4.36Å; I447-I485 HydrophobicContact CG1-CG1 4.1Å; I447-I485 HydrophobicContact CG2-CB 4.32Å; I447-I485 HydrophobicContact CG2-CD1 3.69Å; I447-I485 HydrophobicContact CG2-CG1 3.56Å; I447-I485 HydrophobicContact CG2-CG2 3.79Å; I447-I488 HydrophobicContact CD1-CB 4.21Å; I447-I488 HydrophobicContact CD1-CG1 4.25Å; I447-I488 HydrophobicContact CD1-CG2 3.8Å
448F71.6Confident78.2Confident14 Ų1436.5 Ų36.56%0.06117%0.169CC..THydrogen-bonded Turntrans-99.311.2-175.7-54.8-60000113.7S444 Q446 P450 F455 L465 A501 F503S444-F448 WeakPolarHBondContact O-CD2 2.75Å; S444-F448 PolarHBondContact O-N 2.82Å; Q446-F448 PolarHBondContact O-N 2.7Å; Q446-F448 VanDerWaalsContact O-N 3.11Å; F448-P450 VanDerWaalsContact O-CD 3.28Å; F448-P450 WeakPolarHBondContact O-CD 3.48Å; F448-F455 AromaticContact CD1-CD2 3.54Å; F448-F455 HydrophobicContact CD1-CD2 3.54Å; F448-F455 AromaticContact CD1-CE2 3.66Å; F448-F455 HydrophobicContact CD1-CE2 3.66Å; F448-F455 HydrophobicContact CD1-CG 4.01Å; F448-F455 HydrophobicContact CD1-CZ 4.26Å; F448-F455 AromaticContact CE1-CD2 3.97Å; F448-F455 HydrophobicContact CE1-CD2 3.97Å; F448-F455 HydrophobicContact CE1-CE1 4.37Å; F448-F455 AromaticContact CE1-CE2 3.59Å; F448-F455 HydrophobicContact CE1-CE2 3.59Å; F448-F455 HydrophobicContact CE1-CG 4.47Å; F448-F455 AromaticContact CE1-CZ 3.83Å; F448-F455 HydrophobicContact CE1-CZ 3.83Å; F448-L465 HydrophobicContact CB-CD1 3.47Å; F448-L465 VanDerWaalsContact CB-CD1 3.47Å; F448-L465 HydrophobicContact CB-CD2 4.42Å; F448-L465 HydrophobicContact CD1-CD1 3.6Å; F448-L465 HydrophobicContact CD2-CD1 4.2Å; F448-L465 HydrophobicContact CE1-CD1 4.45Å; F448-L465 HydrophobicContact CG-CD1 3.45Å; F448-L465 VanDerWaalsContact CG-CD1 3.45Å; F448-A501 HydrophobicContact CD2-CB 3.19Å; F448-A501 HydrophobicContact CE1-CB 4.32Å; F448-A501 HydrophobicContact CE2-CB 2.97Å; F448-A501 HydrophobicContact CG-CB 4.03Å; F448-A501 HydrophobicContact CZ-CB 3.6Å; F448-F503 HydrophobicContact CD1-CE1 4.2Å; F448-F503 AromaticContact CE1-CE1 3.36Å; F448-F503 HydrophobicContact CE1-CE1 3.36Å; F448-F503 HydrophobicContact CE1-CE2 4.44Å; F448-F503 AromaticContact CE1-CZ 3.33Å; F448-F503 HydrophobicContact CE1-CZ 3.33Å; F448-F503 HydrophobicContact CZ-CE1 4.01Å; F448-F503 HydrophobicContact CZ-CE2 4.29Å; F448-F503 AromaticContact CZ-CZ 3.51Å; F448-F503 HydrophobicContact CZ-CZ 3.51Å
449N69.8Low76.9Confident40 Ų4037.5 Ų37.521%0.21419%0.187CC..  trans-64.1119.6172.3-175.9-19.8000109.4H445 Q446 Y451 Y452H445-N449 PolarHBondContact O-N 3.17Å; Q446-N449 WeakPolarHBondContact O-CB 3.33Å; Q446-N449 PolarHBondContact O-N 2.75Å; N449-Y451 PolarHBondContact O-N 3.23Å; N449-Y451 WeakPolarHBondContact OD1-CB 3.21Å; N449-Y451 WeakPolarHBondContact OD1-CD2 3.39Å; N449-Y451 PolarHBondContact OD1-N 3.35Å; N449-Y452 HydrophobicContact CB-CD2 3.78Å; N449-Y452 HydrophobicContact CB-CE2 3.95Å; N449-Y452 PolarHBondContact O-N 3.48Å
450P63.3Low75.1Confident57 Ų5740.1 Ų40.137%0.3720%0.203SC..G310 helixtrans-55.2-24.7-179.5-2634.5000113.6F448 Y452 G453 Y457F448-P450 VanDerWaalsContact O-CD 3.28Å; F448-P450 WeakPolarHBondContact O-CD 3.48Å; P450-Y452 PolarHBondContact O-N 2.81Å; P450-G453 PolarHBondContact O-N 3.33Å; P450-Y457 HydrophobicContact CG-CE2 3.75Å
451Y64Low73.4Confident166 Ų16642.8 Ų42.865%0.65122%0.217SC*.G310 helixtrans-66.6-20.7179.1-68.9-64.9000114.5L96 N449 G453L96-Y451 HydrophobicContact CD1-CD1 3.67Å; L96-Y451 HydrophobicContact CD1-CD2 3.36Å; L96-Y451 HydrophobicContact CD1-CE1 3.53Å; L96-Y451 HydrophobicContact CD1-CE2 3.22Å; L96-Y451 HydrophobicContact CD1-CG 3.6Å; L96-Y451 HydrophobicContact CD2-CE1 4.32Å; L96-Y451 HydrophobicContact CD2-CE2 3.97Å; L96-Y451 VanDerWaalsContact CD2-OH 3.27Å; L96-Y451 WeakPolarHBondContact CD2-OH 3.33Å; L96-Y451 HydrophobicContact CG-CE1 4.34Å; L96-Y451 HydrophobicContact CG-CE2 4.2Å; N449-Y451 PolarHBondContact O-N 3.23Å; N449-Y451 WeakPolarHBondContact OD1-CB 3.21Å; N449-Y451 WeakPolarHBondContact OD1-CD2 3.39Å; N449-Y451 PolarHBondContact OD1-N 3.35Å; Y451-G453 PolarHBondContact O-N 3.03Å
452Y70.6Confident72.1Confident26 Ų2648 Ų4810%0.10225%0.246CC..G310 helixtrans-74.8-12.7171.2-67.8-59.7000112.5L37 F401 E402 Q446 N449 P450 L454L37-Y452 HydrophobicContact CD1-CD1 4.07Å; L37-Y452 HydrophobicContact CD1-CE1 3.47Å; L37-Y452 VanDerWaalsContact CD1-CE1 3.47Å; L37-Y452 HydrophobicContact CD2-CD1 4.01Å; L37-Y452 HydrophobicContact CD2-CE1 4.26Å; L37-Y452 HydrophobicContact CG-CE1 4.44Å; F401-Y452 WeakPolarHBondContact CB-OH 3.46Å; F401-Y452 AromaticContact CD1-CE1 3.96Å; F401-Y452 HydrophobicContact CD1-CE1 3.96Å; F401-Y452 HydrophobicContact CD1-CE2 4.28Å; F401-Y452 AromaticContact CD1-CZ 3.73Å; F401-Y452 HydrophobicContact CD2-CE2 4.2Å; F401-Y452 HydrophobicContact CE1-CD1 4.37Å; F401-Y452 HydrophobicContact CE1-CE1 4.14Å; F401-Y452 HydrophobicContact CE2-CE2 4.45Å; F401-Y452 HydrophobicContact CG-CE2 4.11Å; F401-Y452 AromaticContact CG-CZ 3.83Å; E402-Y452 PolarHBondContact OE1-OH 3.49Å; Q446-Y452 HydrophobicContact CB-CE2 4.35Å; Q446-Y452 WeakPolarHBondContact O-CD2 3.31Å; Q446-Y452 WeakPolarHBondContact O-CE2 3.29Å; N449-Y452 HydrophobicContact CB-CD2 3.78Å; N449-Y452 HydrophobicContact CB-CE2 3.95Å; N449-Y452 PolarHBondContact O-N 3.48Å; P450-Y452 PolarHBondContact O-N 2.81Å; Y452-L454 PolarHBondContact O-N 3.26Å; Y452-L454 VanDerWaalsContact O-N 3.16Å
453G72.9Confident71Confident9 Ų954.3 Ų54.39%0.09327%0.268CS..SBendtrans6514.2178.700000114P450 Y451 N468 S471P450-G453 PolarHBondContact O-N 3.33Å; Y451-G453 PolarHBondContact O-N 3.03Å; G453-N468 WeakPolarHBondContact O-CB 3.45Å; G453-N468 PolarHBondContact O-ND2 2.81Å; G453-S471 WeakPolarHBondContact O-CA 3.4Å; G453-S471 WeakPolarHBondContact O-CB 3.27Å
454L80.4Confident70.1Confident0 Ų055.4 Ų55.40%028%0.275CS..SBendtrans-84.6-36.8-179.6-60.7175.5000111.8Y452 N468 H478 Y481 F482 I485Y452-L454 PolarHBondContact O-N 3.26Å; Y452-L454 VanDerWaalsContact O-N 3.16Å; L454-N468 PolarHBondContact O-N 3.48Å; L454-H478 HydrophobicContact CD2-CB 3.79Å; L454-Y481 HydrophobicContact CD1-CG 4.34Å; L454-F482 HydrophobicContact CB-CE1 3.91Å; L454-F482 HydrophobicContact CB-CZ 4.17Å; L454-F482 HydrophobicContact CD2-CE1 4.37Å; L454-F482 HydrophobicContact CD2-CE2 4.47Å; L454-F482 HydrophobicContact CD2-CZ 4.19Å; L454-F482 WeakPolarHBondContact O-CE1 3.31Å; L454-F482 VanDerWaalsContact O-CZ 3.3Å; L454-F482 WeakPolarHBondContact O-CZ 3.28Å; L454-I485 HydrophobicContact CD1-CD1 3.68Å
455F79.9Confident69.5Low9 Ų955.9 Ų55.94%0.03928%0.277CS..EExtended strand (participates in β ladder)trans-129.6156-179.8-58-81.5000110.5I447 F448 L465 Q466 I467 F482 I485 F503I447-F455 HydrophobicContact CG2-CE2 3.88Å; F448-F455 AromaticContact CD1-CD2 3.54Å; F448-F455 HydrophobicContact CD1-CD2 3.54Å; F448-F455 AromaticContact CD1-CE2 3.66Å; F448-F455 HydrophobicContact CD1-CE2 3.66Å; F448-F455 HydrophobicContact CD1-CG 4.01Å; F448-F455 HydrophobicContact CD1-CZ 4.26Å; F448-F455 AromaticContact CE1-CD2 3.97Å; F448-F455 HydrophobicContact CE1-CD2 3.97Å; F448-F455 HydrophobicContact CE1-CE1 4.37Å; F448-F455 AromaticContact CE1-CE2 3.59Å; F448-F455 HydrophobicContact CE1-CE2 3.59Å; F448-F455 HydrophobicContact CE1-CG 4.47Å; F448-F455 AromaticContact CE1-CZ 3.83Å; F448-F455 HydrophobicContact CE1-CZ 3.83Å; F455-L465 HydrophobicContact CB-CD2 4.33Å; F455-Q466 CarbonylContact C-O 3.56Å; F455-Q466 WeakPolarHBondContact CA-O 3.41Å; F455-Q466 WeakPolarHBondContact CB-O 3.39Å; F455-Q466 WeakPolarHBondContact CD1-O 3.49Å; F455-I467 HydrophobicContact CD1-CG1 4.45Å; F455-I467 HydrophobicContact CE1-CG1 4.12Å; F455-F482 HydrophobicContact CE1-CE1 4.15Å; F455-F482 HydrophobicContact CE2-CE1 4.42Å; F455-F482 HydrophobicContact CZ-CD1 4.22Å; F455-F482 AromaticContact CZ-CE1 3.99Å; F455-F482 HydrophobicContact CZ-CE1 3.99Å; F455-I485 HydrophobicContact CE2-CD1 3.66Å; F455-I485 HydrophobicContact CZ-CD1 4.06Å; F455-I485 HydrophobicContact CZ-CG2 4.33Å; F455-F503 HydrophobicContact CD1-CE1 4.01Å; F455-F503 HydrophobicContact CE1-CD1 4.3Å; F455-F503 AromaticContact CE1-CE1 3.49Å; F455-F503 HydrophobicContact CE1-CE1 3.49Å; F455-F503 VanDerWaalsContact CE1-CE1 3.49Å; F455-F503 HydrophobicContact CE1-CZ 4.32Å; F455-F503 AromaticContact CZ-CE1 3.89Å; F455-F503 HydrophobicContact CZ-CE1 3.89Å; F455-F503 HydrophobicContact CZ-CZ 4.34Å
456E70.4Confident69.2Low66 Ų6653.1 Ų53.131%0.30827%0.265SS..EExtended strand (participates in β ladder)trans-128.5160.3170.363.4-173.3-163.400109.7L465 Q466E456-L465 WeakPolarHBondContact O-CA 3.32Å; E456-Q466 HydrophobicContact CG-CG 3.53Å; E456-Q466 PolarHBondContact N-O 3.27Å; E456-Q466 PolarHBondContact O-N 3.01Å; E456-Q466 PolarHBondContact OE1-NE2 2.57Å
457Y72Confident69.2Low112 Ų11253.6 Ų53.644%0.43927%0.268SS..EExtended strand (participates in β ladder)trans-70.5145.9171.2-66.4-72.5000109.6P450 N462 T464 L465P450-Y457 HydrophobicContact CG-CE2 3.75Å; Y457-N462 VanDerWaalsContact CD1-O 3.31Å; Y457-N462 WeakPolarHBondContact CD1-O 3.47Å; Y457-N462 WeakPolarHBondContact CE1-O 3.41Å; Y457-T464 WeakPolarHBondContact CA-O 3.12Å; Y457-L465 HydrophobicContact CD1-CD2 4.02Å; Y457-L465 HydrophobicContact CE1-CD2 4.08Å
458S64.2Low68.9Low4 Ų454.3 Ų54.33%0.02827%0.272CS..  trans-59.3153.9167.8820000110.2T460 D461 T464S458-T460 PolarHBondContact O-N 3.4Å; S458-T460 PolarHBondContact OG-N 3.12Å; S458-T460 PolarHBondContact OG-OG1 2.79Å; S458-D461 VanDerWaalsContact O-O 3.07Å; S458-D461 PolarHBondContact OG-N 3.43Å; S458-D461 VanDerWaalsContact OG-N 3.09Å; S458-D461 PolarHBondContact OG-O 3.19Å; S458-D461 PolarHBondContact OG-OD1 2.85Å; S458-T464 WeakPolarHBondContact CB-OG1 3.31Å; S458-T464 PolarHBondContact N-O 3Å; S458-T464 PolarHBondContact OG-OG1 3.01Å
459A57.3Low69Low76 Ų7657.8 Ų57.863%0.62830%0.296SS*.SBendtrans-68-21.3174.400000112.1V524 D525A459-V524 PolarHBondContact N-O 3.39Å; A459-V524 VanDerWaalsContact N-O 3.07Å; A459-D525 HydrophobicContact CB-CB 4.18Å
460T53.2Low69.1Low55 Ų5557.9 Ų57.934%0.33730%0.295SS..SBendtrans-82.9-31-174.863.80000114.9S458 E522 S523 N526S458-T460 PolarHBondContact O-N 3.4Å; S458-T460 PolarHBondContact OG-N 3.12Å; S458-T460 PolarHBondContact OG-OG1 2.79Å; T460-E522 VanDerWaalsContact CG2-O 3.3Å; T460-E522 WeakPolarHBondContact CG2-O 3.36Å; T460-S523 PolarHBondContact OG1-O 2.97Å; T460-N526 HydrophobicContact CG2-CB 3.72Å; T460-N526 VanDerWaalsContact CG2-N 3.26Å
461D57.3Low69.9Low57 Ų5755.4 Ų55.431%0.30528%0.279SS..  trans-153.4153.1178.567.634.3000112.5S458 Y463 T464S458-D461 VanDerWaalsContact O-O 3.07Å; S458-D461 PolarHBondContact OG-N 3.43Å; S458-D461 VanDerWaalsContact OG-N 3.09Å; S458-D461 PolarHBondContact OG-O 3.19Å; S458-D461 PolarHBondContact OG-OD1 2.85Å; D461-Y463 HydrophobicContact CB-CD2 4.31Å; D461-Y463 PolarHBondContact O-N 3.31Å; D461-Y463 PolarHBondContact OD1-N 3.47Å; D461-T464 VanDerWaalsContact OD1-CB 3.32Å; D461-T464 WeakPolarHBondContact OD1-CB 3.33Å; D461-T464 WeakPolarHBondContact OD1-CG2 3.16Å; D461-T464 PolarHBondContact OD1-N 3.29Å; D461-T464 PolarHBondContact OD1-OG1 3.49Å
462N58.2Low70.5Confident128 Ų12853.8 Ų53.868%0.68428%0.277SS*.SBendtrans-81.817.6177-65.1-22.7000112.6Y457Y457-N462 VanDerWaalsContact CD1-O 3.31Å; Y457-N462 WeakPolarHBondContact CD1-O 3.47Å; Y457-N462 WeakPolarHBondContact CE1-O 3.41Å
463Y65.7Low70.7Confident176 Ų17655.6 Ų55.669%0.6930%0.297SS*.SBendtrans-121.2-29.1-170.7-62.4-73.6000113.6D461D461-Y463 HydrophobicContact CB-CD2 4.31Å; D461-Y463 PolarHBondContact O-N 3.31Å; D461-Y463 PolarHBondContact OD1-N 3.47Å
464T70.2Confident70.6Confident23 Ų2357.7 Ų57.714%0.14131%0.31CS..EExtended strand (participates in β ladder)trans-99.8146.9178.7640000111.1Y457 S458 D461 F502Y457-T464 WeakPolarHBondContact CA-O 3.12Å; S458-T464 WeakPolarHBondContact CB-OG1 3.31Å; S458-T464 PolarHBondContact N-O 3Å; S458-T464 PolarHBondContact OG-OG1 3.01Å; D461-T464 VanDerWaalsContact OD1-CB 3.32Å; D461-T464 WeakPolarHBondContact OD1-CB 3.33Å; D461-T464 WeakPolarHBondContact OD1-CG2 3.16Å; D461-T464 PolarHBondContact OD1-N 3.29Å; D461-T464 PolarHBondContact OD1-OG1 3.49Å; T464-F502 CarbonylContact C-O 3.56Å; T464-F502 WeakPolarHBondContact CA-O 3.48Å; T464-F502 HydrophobicContact CG2-CB 4.26Å
465L75.2Confident70.1Confident10 Ų1058.2 Ų58.25%0.05231%0.313CS..EExtended strand (participates in β ladder)trans-118.6143.8-169.8-65.2155.6000111.2F448 F455 E456 Y457 A501 F502 F503 I504F448-L465 HydrophobicContact CB-CD1 3.47Å; F448-L465 VanDerWaalsContact CB-CD1 3.47Å; F448-L465 HydrophobicContact CB-CD2 4.42Å; F448-L465 HydrophobicContact CD1-CD1 3.6Å; F448-L465 HydrophobicContact CD2-CD1 4.2Å; F448-L465 HydrophobicContact CE1-CD1 4.45Å; F448-L465 HydrophobicContact CG-CD1 3.45Å; F448-L465 VanDerWaalsContact CG-CD1 3.45Å; F455-L465 HydrophobicContact CB-CD2 4.33Å; E456-L465 WeakPolarHBondContact O-CA 3.32Å; Y457-L465 HydrophobicContact CD1-CD2 4.02Å; Y457-L465 HydrophobicContact CE1-CD2 4.08Å; L465-A501 HydrophobicContact CD1-CB 4.37Å; L465-F502 PolarHBondContact N-O 2.93Å; L465-F503 HydrophobicContact CB-CD1 4.31Å; L465-F503 CarbonylContact O-C 3.54Å; L465-F503 VanDerWaalsContact O-CA 3.26Å; L465-F503 WeakPolarHBondContact O-CA 3.47Å; L465-I504 PolarHBondContact O-N 2.85Å
466Q74.8Confident70.1Confident31 Ų3162.9 Ų62.915%0.14534%0.344CS..EExtended strand (participates in β ladder)trans-129.9159.9171.369-1772.200111.4F455 E456 N468 I504 V524F455-Q466 CarbonylContact C-O 3.56Å; F455-Q466 WeakPolarHBondContact CA-O 3.41Å; F455-Q466 WeakPolarHBondContact CB-O 3.39Å; F455-Q466 WeakPolarHBondContact CD1-O 3.49Å; E456-Q466 HydrophobicContact CG-CG 3.53Å; E456-Q466 PolarHBondContact N-O 3.27Å; E456-Q466 PolarHBondContact O-N 3.01Å; E456-Q466 PolarHBondContact OE1-NE2 2.57Å; Q466-N468 PolarHBondContact O-N 2.79Å; Q466-I504 HydrophobicContact CB-CD1 3.54Å; Q466-I504 HydrophobicContact CB-CG1 3.91Å; Q466-I504 HydrophobicContact CB-CG2 4.3Å; Q466-V524 VanDerWaalsContact OE1-CG1 3.26Å
467I81.8Confident70.5Confident65 Ų6565.4 Ų65.433%0.33336%0.356SS..EExtended strand (participates in β ladder)trans-60.1130.2173.8-72.7178.7000107.7F455 P469 F482 F507F455-I467 HydrophobicContact CD1-CG1 4.45Å; F455-I467 HydrophobicContact CE1-CG1 4.12Å; I467-P469 VanDerWaalsContact O-CD 3.24Å; I467-P469 WeakPolarHBondContact O-CD 3.44Å; I467-F482 HydrophobicContact CG1-CE1 4.18Å; I467-F482 HydrophobicContact CG1-CZ 4.41Å; I467-F482 HydrophobicContact CG2-CE1 4.45Å; I467-F482 HydrophobicContact CG2-CE2 4.44Å; I467-F482 HydrophobicContact CG2-CZ 3.86Å; I467-F507 HydrophobicContact CD1-CD2 4.39Å; I467-F507 HydrophobicContact CD1-CE2 3.6Å; I467-F507 HydrophobicContact CD1-CZ 4.42Å; I467-F507 HydrophobicContact CG1-CD2 4.44Å; I467-F507 HydrophobicContact CG1-CE2 3.86Å
468N74.2Confident71Confident16 Ų1661 Ų619%0.08634%0.34CS..  trans-67114.5167.9173.64.4000108.4G453 L454 Q466 H470 S471G453-N468 WeakPolarHBondContact O-CB 3.45Å; G453-N468 PolarHBondContact O-ND2 2.81Å; L454-N468 PolarHBondContact O-N 3.48Å; Q466-N468 PolarHBondContact O-N 2.79Å; N468-H470 PolarHBondContact O-N 3.15Å; N468-H470 VanDerWaalsContact O-N 3.14Å; N468-H470 WeakPolarHBondContact OD1-CA 3.49Å; N468-H470 WeakPolarHBondContact OD1-CB 3.46Å; N468-H470 PolarHBondContact OD1-N 2.92Å; N468-S471 WeakPolarHBondContact O-CB 3.41Å; N468-S471 PolarHBondContact O-N 2.92Å; N468-S471 PolarHBondContact O-OG 2.77Å
469P73.2Confident72.1Confident87 Ų8766.7 Ų66.757%0.56537%0.369SS*.THydrogen-bonded Turntrans-60.4-24.3179.425-33000112.2I467I467-P469 VanDerWaalsContact O-CD 3.24Å; I467-P469 WeakPolarHBondContact O-CD 3.44Å
470H72.8Confident73.8Confident43 Ų4364.4 Ų64.420%0.19935%0.348CS..THydrogen-bonded Turntrans-98.116178-46.8-53.4000113.7N468 E472 A473 C474 D551 I553N468-H470 PolarHBondContact O-N 3.15Å; N468-H470 VanDerWaalsContact O-N 3.14Å; N468-H470 WeakPolarHBondContact OD1-CA 3.49Å; N468-H470 WeakPolarHBondContact OD1-CB 3.46Å; N468-H470 PolarHBondContact OD1-N 2.92Å; H470-E472 PolarHBondContact O-N 2.72Å; H470-E472 VanDerWaalsContact O-N 3.1Å; H470-A473 WeakPolarHBondContact O-CB 3.2Å; H470-A473 PolarHBondContact O-N 2.89Å; H470-C474 PolarHBondContact O-N 2.78Å; H470-D551 IonicContact CE1-OD2 3.79Å; H470-D551 PolarHBondContact CE1-OD2 3.31Å; H470-D551 VanDerWaalsContact CE1-OD2 3.32Å; H470-D551 IonicContact NE2-OD1 3.25Å; H470-D551 IonicContact NE2-OD2 3.32Å; H470-I553 HydrophobicContact CB-CG2 4.49Å; H470-I553 WeakPolarHBondContact CE1-CD1 3.43Å; H470-I553 WeakPolarHBondContact CE1-CG1 3.47Å
471S78.9Confident75.5Confident4 Ų462 Ų623%0.02833%0.333CS..Hα-helixtrans-54.8-31.1-179.649.20000113.4G453 N468 C474 N475 H478 F482G453-S471 WeakPolarHBondContact O-CA 3.4Å; G453-S471 WeakPolarHBondContact O-CB 3.27Å; N468-S471 WeakPolarHBondContact O-CB 3.41Å; N468-S471 PolarHBondContact O-N 2.92Å; N468-S471 PolarHBondContact O-OG 2.77Å; S471-C474 PolarHBondContact O-N 2.87Å; S471-N475 PolarHBondContact O-N 2.89Å; S471-H478 WeakPolarHBondContact CB-ND1 3.35Å; S471-H478 PolarHBondContact OG-ND1 2.91Å; S471-F482 WeakPolarHBondContact OG-CE2 3.09Å
472E77.9Confident77Confident133 Ų13361.2 Ų61.262%0.62133%0.327SS*.Hα-helixtrans-62.3-43175.4-173.2172.9-171.100112.2H470 C474 N475 H478H470-E472 PolarHBondContact O-N 2.72Å; H470-E472 VanDerWaalsContact O-N 3.1Å; E472-C474 VanDerWaalsContact C-N 3.32Å; E472-C474 PolarHBondContact O-N 2.64Å; E472-N475 CarbonylContact O-C 3.49Å; E472-N475 VanDerWaalsContact O-C 3.22Å; E472-N475 PolarHBondContact O-N 2.86Å; E472-H478 PolarHBondContact N-ND1 3.11Å
473A74.5Confident78.7Confident63 Ų6360.3 Ų60.352%0.52132%0.318SS..Hα-helixtrans-70.9-30.7179.400000112.1H470 F554H470-A473 WeakPolarHBondContact O-CB 3.2Å; H470-A473 PolarHBondContact O-N 2.89Å; A473-F554 HydrophobicContact CB-CE2 3.38Å; A473-F554 HydrophobicContact CB-CZ 3.72Å
474C71Confident80Confident54 Ų5451.9 Ų51.937%0.36529%0.286SS..Hα-helixtrans-72.4-43171.9-63.20000111.8H470 S471 E472H470-C474 PolarHBondContact O-N 2.78Å; S471-C474 PolarHBondContact O-N 2.87Å; E472-C474 VanDerWaalsContact C-N 3.32Å; E472-C474 PolarHBondContact O-N 2.64Å
475N70.2Confident81Confident11 Ų1151 Ų516%0.05928%0.28CS..  trans-146.8108.6-172.9-179.21.2000111.6S471 E472 E477 H478 Y481S471-N475 PolarHBondContact O-N 2.89Å; E472-N475 CarbonylContact O-C 3.49Å; E472-N475 VanDerWaalsContact O-C 3.22Å; E472-N475 PolarHBondContact O-N 2.86Å; N475-E477 PolarHBondContact O-N 2.92Å; N475-E477 VanDerWaalsContact O-N 3.09Å; N475-E477 PolarHBondContact OD1-N 3.13Å; N475-H478 HydrophobicContact CB-CB 4.32Å; N475-H478 WeakPolarHBondContact O-CB 2.72Å; N475-H478 PolarHBondContact O-N 3.18Å; N475-Y481 WeakPolarHBondContact ND2-CD2 3.38Å; N475-Y481 WeakPolarHBondContact ND2-CE2 3.24Å
476P78.8Confident81.8Confident107 Ų10752.4 Ų52.470%0.69530%0.297SS*.THydrogen-bonded Turntrans-60.2-23.2178.3-25.434.6000114.7H478P476-H478 VanDerWaalsContact C-N 3.34Å
477E80.3Confident82.8Confident118 Ų11852.6 Ų52.655%0.55130%0.296SS*.THydrogen-bonded Turntrans-93.79.7178.6-62.2-71148.300112.1N475 L479 S480 Y481N475-E477 PolarHBondContact O-N 2.92Å; N475-E477 VanDerWaalsContact O-N 3.09Å; N475-E477 PolarHBondContact OD1-N 3.13Å; E477-L479 PolarHBondContact O-N 3.3Å; E477-S480 WeakPolarHBondContact O-CB 2.91Å; E477-S480 PolarHBondContact O-N 2.86Å; E477-Y481 HydrophobicContact CB-CD2 4.2Å; E477-Y481 HydrophobicContact CB-CE2 3.92Å; E477-Y481 VanDerWaalsContact O-CD2 3.32Å; E477-Y481 WeakPolarHBondContact O-CD2 3.15Å; E477-Y481 PolarHBondContact O-N 3.07Å
478H81.6Confident83.4Confident21 Ų2149.5 Ų49.510%0.09728%0.281CS..Hα-helixtrans-49.3-37.4-175.171.2142.9000113.5L454 S471 E472 N475 P476 S480 Y481 F482L454-H478 HydrophobicContact CD2-CB 3.79Å; S471-H478 WeakPolarHBondContact CB-ND1 3.35Å; S471-H478 PolarHBondContact OG-ND1 2.91Å; E472-H478 PolarHBondContact N-ND1 3.11Å; N475-H478 HydrophobicContact CB-CB 4.32Å; N475-H478 WeakPolarHBondContact O-CB 2.72Å; N475-H478 PolarHBondContact O-N 3.18Å; P476-H478 VanDerWaalsContact C-N 3.34Å; H478-S480 VanDerWaalsContact C-N 3.33Å; H478-S480 PolarHBondContact O-N 2.86Å; H478-Y481 CarbonylContact O-C 3.59Å; H478-Y481 WeakPolarHBondContact O-CA 3.48Å; H478-Y481 WeakPolarHBondContact O-CB 3.27Å; H478-Y481 PolarHBondContact O-N 3.14Å; H478-Y481 VanDerWaalsContact O-N 3.1Å; H478-F482 HydrophobicContact CB-CD2 4.37Å; H478-F482 HydrophobicContact CB-CE2 4.06Å; H478-F482 AromaticContact ND1-CE2 3.57Å; H478-F482 WeakPolarHBondContact O-CD2 3.24Å; H478-F482 WeakPolarHBondContact O-CG 3.31Å; H478-F482 PolarHBondContact O-N 2.8Å
479L87.9Confident84.2Confident122 Ų12249.5 Ų49.564%0.63928%0.28SS*.Hα-helixtrans-62.1-38.7177.4-62.1-175.4000112.6E477 Y481 F482 H483E477-L479 PolarHBondContact O-N 3.3Å; L479-Y481 VanDerWaalsContact C-N 3.31Å; L479-F482 HydrophobicContact CD2-CD2 4.49Å; L479-F482 PolarHBondContact O-N 2.73Å; L479-H483 WeakPolarHBondContact O-CB 3.22Å; L479-H483 PolarHBondContact O-N 2.69Å
480S91.5Very high85.1Confident29 Ų2947.1 Ų47.120%0.20327%0.272CS..Hα-helixtrans-67.5-36175.7-169.20000111.1Y405 E477 H478 H483 F484Y405-S480 PolarHBondContact OH-OG 3.18Å; E477-S480 WeakPolarHBondContact O-CB 2.91Å; E477-S480 PolarHBondContact O-N 2.86Å; H478-S480 VanDerWaalsContact C-N 3.33Å; H478-S480 PolarHBondContact O-N 2.86Å; S480-H483 WeakPolarHBondContact O-CB 3.24Å; S480-H483 PolarHBondContact O-N 2.84Å; S480-F484 WeakPolarHBondContact O-CB 3.47Å; S480-F484 PolarHBondContact O-N 3.3Å
481Y89.5Confident86.1Confident3 Ų345.5 Ų45.51%0.01226%0.264CS..Hα-helixtrans-68.9-43.5173.4-72.4-75.2000112.5L36 L37 F401 Y405 L454 N475 E477 H478 L479 H483 F484 I485L36-Y481 PolarHBondContact O-OH 3.35Å; L37-Y481 HydrophobicContact CD2-CD1 4.22Å; L37-Y481 HydrophobicContact CD2-CD2 4.35Å; L37-Y481 HydrophobicContact CD2-CE1 3.47Å; L37-Y481 VanDerWaalsContact CD2-CE1 3.47Å; L37-Y481 HydrophobicContact CD2-CE2 3.62Å; L37-Y481 WeakPolarHBondContact CD2-OH 3.41Å; L37-Y481 HydrophobicContact CG-CE1 4.19Å; L37-Y481 VanDerWaalsContact CG-OH 3.25Å; L37-Y481 WeakPolarHBondContact CG-OH 3.37Å; F401-Y481 AromaticContact CE1-CD1 3.65Å; F401-Y481 HydrophobicContact CE1-CD1 3.65Å; F401-Y481 AromaticContact CE1-CE1 3.62Å; F401-Y481 HydrophobicContact CE1-CE1 3.62Å; F401-Y481 AromaticContact CZ-CD1 3.81Å; F401-Y481 HydrophobicContact CZ-CD1 3.81Å; F401-Y481 HydrophobicContact CZ-CE1 4.26Å; Y405-Y481 HydrophobicContact CD1-CE1 4.48Å; Y405-Y481 AromaticContact CD2-CD1 3.71Å; Y405-Y481 HydrophobicContact CD2-CD1 3.71Å; Y405-Y481 AromaticContact CD2-CE1 3.53Å; Y405-Y481 HydrophobicContact CD2-CE1 3.53Å; Y405-Y481 AromaticContact CE2-CD1 3.75Å; Y405-Y481 HydrophobicContact CE2-CD1 3.75Å; Y405-Y481 AromaticContact CE2-CE1 3.64Å; Y405-Y481 HydrophobicContact CE2-CE1 3.64Å; Y405-Y481 HydrophobicContact CE2-CG 4.32Å; Y405-Y481 AromaticContact CG-CE1 3.98Å; Y405-Y481 HydrophobicContact CG-CE1 3.98Å; L454-Y481 HydrophobicContact CD1-CG 4.34Å; N475-Y481 WeakPolarHBondContact ND2-CD2 3.38Å; N475-Y481 WeakPolarHBondContact ND2-CE2 3.24Å; E477-Y481 HydrophobicContact CB-CD2 4.2Å; E477-Y481 HydrophobicContact CB-CE2 3.92Å; E477-Y481 VanDerWaalsContact O-CD2 3.32Å; E477-Y481 WeakPolarHBondContact O-CD2 3.15Å; E477-Y481 PolarHBondContact O-N 3.07Å; H478-Y481 CarbonylContact O-C 3.59Å; H478-Y481 WeakPolarHBondContact O-CA 3.48Å; H478-Y481 WeakPolarHBondContact O-CB 3.27Å; H478-Y481 PolarHBondContact O-N 3.14Å; H478-Y481 VanDerWaalsContact O-N 3.1Å; L479-Y481 VanDerWaalsContact C-N 3.31Å; Y481-H483 VanDerWaalsContact C-N 3.25Å; Y481-H483 PolarHBondContact O-N 2.78Å; Y481-F484 WeakPolarHBondContact O-CB 3.46Å; Y481-F484 PolarHBondContact O-N 3.25Å; Y481-F484 VanDerWaalsContact O-N 3.15Å; Y481-I485 WeakPolarHBondContact O-CD1 3.22Å; Y481-I485 WeakPolarHBondContact O-CG1 3.44Å; Y481-I485 PolarHBondContact O-N 3.15Å
482F89.9Confident86.7Confident41 Ų4145.3 Ų45.318%0.1826%0.263CS..Hα-helixtrans-60.3-38172.2-70.6-51.8000111.6L454 F455 I467 S471 H478 L479 I485 G486L454-F482 HydrophobicContact CB-CE1 3.91Å; L454-F482 HydrophobicContact CB-CZ 4.17Å; L454-F482 HydrophobicContact CD2-CE1 4.37Å; L454-F482 HydrophobicContact CD2-CE2 4.47Å; L454-F482 HydrophobicContact CD2-CZ 4.19Å; L454-F482 WeakPolarHBondContact O-CE1 3.31Å; L454-F482 VanDerWaalsContact O-CZ 3.3Å; L454-F482 WeakPolarHBondContact O-CZ 3.28Å; F455-F482 HydrophobicContact CE1-CE1 4.15Å; F455-F482 HydrophobicContact CE2-CE1 4.42Å; F455-F482 HydrophobicContact CZ-CD1 4.22Å; F455-F482 AromaticContact CZ-CE1 3.99Å; F455-F482 HydrophobicContact CZ-CE1 3.99Å; I467-F482 HydrophobicContact CG1-CE1 4.18Å; I467-F482 HydrophobicContact CG1-CZ 4.41Å; I467-F482 HydrophobicContact CG2-CE1 4.45Å; I467-F482 HydrophobicContact CG2-CE2 4.44Å; I467-F482 HydrophobicContact CG2-CZ 3.86Å; S471-F482 WeakPolarHBondContact OG-CE2 3.09Å; H478-F482 HydrophobicContact CB-CD2 4.37Å; H478-F482 HydrophobicContact CB-CE2 4.06Å; H478-F482 AromaticContact ND1-CE2 3.57Å; H478-F482 WeakPolarHBondContact O-CD2 3.24Å; H478-F482 WeakPolarHBondContact O-CG 3.31Å; H478-F482 PolarHBondContact O-N 2.8Å; L479-F482 HydrophobicContact CD2-CD2 4.49Å; L479-F482 PolarHBondContact O-N 2.73Å; F482-I485 HydrophobicContact CD1-CD1 4.35Å; F482-I485 PolarHBondContact O-N 2.64Å; F482-G486 PolarHBondContact O-N 3.48Å
483H92.1Very high87.3Confident109 Ų10940.8 Ų40.851%0.50524%0.243SC..Hα-helixtrans-62.3-47.9172.5-174.277.4000111.6L479 S480 Y481 I485 G486 R487L479-H483 WeakPolarHBondContact O-CB 3.22Å; L479-H483 PolarHBondContact O-N 2.69Å; S480-H483 WeakPolarHBondContact O-CB 3.24Å; S480-H483 PolarHBondContact O-N 2.84Å; Y481-H483 VanDerWaalsContact C-N 3.25Å; Y481-H483 PolarHBondContact O-N 2.78Å; H483-I485 PolarHBondContact O-N 3.04Å; H483-G486 PolarHBondContact O-N 2.64Å; H483-R487 WeakPolarHBondContact O-CG 3.29Å; H483-R487 PolarHBondContact O-N 3.23Å
484F94Very high88.1Confident0 Ų040.4 Ų40.40%023%0.228CC..Hα-helixtrans-55.4-47.3174161.5-109.6000112.3F401 Y405 I408 M409 L443 I447 S480 Y481 G486 R487 I488F401-F484 HydrophobicContact CD2-CE1 4.26Å; F401-F484 HydrophobicContact CE2-CD1 4.41Å; F401-F484 AromaticContact CE2-CE1 3.76Å; F401-F484 HydrophobicContact CE2-CE1 3.76Å; F401-F484 HydrophobicContact CZ-CD1 4.28Å; F401-F484 HydrophobicContact CZ-CE1 4Å; Y405-F484 VanDerWaalsContact CA-CE2 3.41Å; Y405-F484 HydrophobicContact CD2-CB 3.65Å; Y405-F484 AromaticContact CD2-CD1 3.91Å; Y405-F484 HydrophobicContact CD2-CD1 3.91Å; Y405-F484 HydrophobicContact CD2-CD2 4.06Å; Y405-F484 AromaticContact CD2-CG 3.6Å; Y405-F484 HydrophobicContact CD2-CG 3.6Å; Y405-F484 HydrophobicContact CE2-CB 3.9Å; Y405-F484 HydrophobicContact CE2-CG 4.36Å; Y405-F484 HydrophobicContact CG-CG 4.48Å; I408-F484 HydrophobicContact CB-CD2 4.01Å; I408-F484 HydrophobicContact CB-CE2 3.97Å; I408-F484 HydrophobicContact CD1-CD2 4.3Å; I408-F484 HydrophobicContact CD1-CE2 3.55Å; I408-F484 HydrophobicContact CD1-CZ 4.45Å; I408-F484 HydrophobicContact CG1-CE2 4.34Å; I408-F484 HydrophobicContact CG2-CD2 3.95Å; I408-F484 HydrophobicContact CG2-CE2 4.29Å; M409-F484 HydrophobicContact CG-CB 4.31Å; M409-F484 HydrophobicContact SD-CB 3.93Å; L443-F484 HydrophobicContact CD1-CZ 4.26Å; L443-F484 HydrophobicContact CD2-CZ 4.1Å; I447-F484 HydrophobicContact CG1-CE1 4.43Å; S480-F484 WeakPolarHBondContact O-CB 3.47Å; S480-F484 PolarHBondContact O-N 3.3Å; Y481-F484 WeakPolarHBondContact O-CB 3.46Å; Y481-F484 PolarHBondContact O-N 3.25Å; Y481-F484 VanDerWaalsContact O-N 3.15Å; F484-G486 VanDerWaalsContact C-N 3.35Å; F484-G486 PolarHBondContact O-N 3.44Å; F484-R487 WeakPolarHBondContact O-CB 3.42Å; F484-R487 PolarHBondContact O-N 2.75Å; F484-R487 VanDerWaalsContact O-N 3.11Å; F484-I488 HydrophobicContact CD2-CG1 4.31Å; F484-I488 HydrophobicContact CE1-CG1 4.38Å; F484-I488 HydrophobicContact CE2-CD1 4.1Å; F484-I488 HydrophobicContact CE2-CG1 3.83Å; F484-I488 HydrophobicContact CZ-CD1 4.28Å; F484-I488 HydrophobicContact CZ-CG1 3.88Å; F484-I488 PolarHBondContact O-N 2.95Å
485I91.7Very high89Confident4 Ų440 Ų402%0.02122%0.221CC..Hα-helixtrans-62.9-42.9178.1-65.9158.9000110.6I447 L454 F455 Y481 F482 H483 R487 I488 I489I447-I485 HydrophobicContact CB-CG1 4.45Å; I447-I485 HydrophobicContact CD1-CG1 4.36Å; I447-I485 HydrophobicContact CG1-CG1 4.1Å; I447-I485 HydrophobicContact CG2-CB 4.32Å; I447-I485 HydrophobicContact CG2-CD1 3.69Å; I447-I485 HydrophobicContact CG2-CG1 3.56Å; I447-I485 HydrophobicContact CG2-CG2 3.79Å; L454-I485 HydrophobicContact CD1-CD1 3.68Å; F455-I485 HydrophobicContact CE2-CD1 3.66Å; F455-I485 HydrophobicContact CZ-CD1 4.06Å; F455-I485 HydrophobicContact CZ-CG2 4.33Å; Y481-I485 WeakPolarHBondContact O-CD1 3.22Å; Y481-I485 WeakPolarHBondContact O-CG1 3.44Å; Y481-I485 PolarHBondContact O-N 3.15Å; F482-I485 HydrophobicContact CD1-CD1 4.35Å; F482-I485 PolarHBondContact O-N 2.64Å; H483-I485 PolarHBondContact O-N 3.04Å; I485-R487 VanDerWaalsContact C-N 3.27Å; I485-R487 PolarHBondContact O-N 2.81Å; I485-I488 WeakPolarHBondContact O-CB 3.42Å; I485-I488 PolarHBondContact O-N 2.96Å; I485-I488 VanDerWaalsContact O-N 3.11Å; I485-I489 HydrophobicContact CG2-CD1 3.9Å; I485-I489 HydrophobicContact CG2-CG1 4.45Å; I485-I489 WeakPolarHBondContact O-CG1 3.11Å; I485-I489 PolarHBondContact O-N 2.67Å
486G92.2Very high89.7Confident40 Ų4040.5 Ų40.541%0.41223%0.229SC..Hα-helixtrans-58.8-38.4173.500000112.4F482 H483 F484 I489 G490F482-G486 PolarHBondContact O-N 3.48Å; H483-G486 PolarHBondContact O-N 2.64Å; F484-G486 VanDerWaalsContact C-N 3.35Å; F484-G486 PolarHBondContact O-N 3.44Å; G486-I489 PolarHBondContact O-N 2.94Å; G486-G490 PolarHBondContact O-N 2.81Å
487R94.5Very high90.1Very high34 Ų3436.7 Ų36.713%0.12820%0.202CC..Hα-helixtrans-67.2-41.1173.1-65.5-173.787.2-170.25.4111.9I408 K411 D413 L416 H483 F484 I485 G490 M491I408-R487 HydrophobicContact CG2-CB 3.99Å; I408-R487 PolarHBondContact O-NH1 3.5Å; K411-R487 PolarHBondContact O-NH1 2.74Å; K411-R487 VanDerWaalsContact O-NH1 3.11Å; K411-R487 PolarHBondContact O-NH2 2.62Å; D413-R487 IonicContact OD1-CZ 3.86Å; D413-R487 IonicContact OD1-NE 3.44Å; D413-R487 IonicContact OD1-NH2 3.55Å; D413-R487 PolarHBondContact OD1-NH2 2.85Å; L416-R487 VanDerWaalsContact CD1-CZ 3.46Å; H483-R487 WeakPolarHBondContact O-CG 3.29Å; H483-R487 PolarHBondContact O-N 3.23Å; F484-R487 WeakPolarHBondContact O-CB 3.42Å; F484-R487 PolarHBondContact O-N 2.75Å; F484-R487 VanDerWaalsContact O-N 3.11Å; I485-R487 VanDerWaalsContact C-N 3.27Å; I485-R487 PolarHBondContact O-N 2.81Å; R487-G490 PolarHBondContact O-N 3.08Å; R487-M491 WeakPolarHBondContact O-CB 3.35Å; R487-M491 VanDerWaalsContact O-CG 3.24Å; R487-M491 WeakPolarHBondContact O-CG 3.47Å; R487-M491 PolarHBondContact O-N 3.13Å
488I94.3Very high90.3Very high1 Ų132.8 Ų32.81%0.00518%0.184CC..Hα-helixtrans-59.3-47.6173.7-71-65.2000111.3I408 W439 F440 L443 I447 F484 I485 G490 M491 A492 L499I408-I488 HydrophobicContact CD1-CD1 3.13Å; I408-I488 HydrophobicContact CD1-CG1 4.08Å; W439-I488 HydrophobicContact CH2-CD1 3.48Å; W439-I488 VanDerWaalsContact CH2-CD1 3.48Å; W439-I488 HydrophobicContact CZ2-CD1 4.03Å; W439-I488 HydrophobicContact CZ3-CD1 4.33Å; F440-I488 HydrophobicContact CD1-CG2 4.3Å; F440-I488 HydrophobicContact CE1-CG2 4.23Å; L443-I488 HydrophobicContact CD2-CD1 3.38Å; L443-I488 HydrophobicContact CD2-CG1 3.9Å; L443-I488 HydrophobicContact CD2-CG2 4.47Å; I447-I488 HydrophobicContact CD1-CB 4.21Å; I447-I488 HydrophobicContact CD1-CG1 4.25Å; I447-I488 HydrophobicContact CD1-CG2 3.8Å; F484-I488 HydrophobicContact CD2-CG1 4.31Å; F484-I488 HydrophobicContact CE1-CG1 4.38Å; F484-I488 HydrophobicContact CE2-CD1 4.1Å; F484-I488 HydrophobicContact CE2-CG1 3.83Å; F484-I488 HydrophobicContact CZ-CD1 4.28Å; F484-I488 HydrophobicContact CZ-CG1 3.88Å; F484-I488 PolarHBondContact O-N 2.95Å; I485-I488 WeakPolarHBondContact O-CB 3.42Å; I485-I488 PolarHBondContact O-N 2.96Å; I485-I488 VanDerWaalsContact O-N 3.11Å; I488-G490 VanDerWaalsContact C-N 3.34Å; I488-G490 PolarHBondContact O-N 3.42Å; I488-M491 HydrophobicContact CD1-SD 4.5Å; I488-M491 WeakPolarHBondContact O-CB 3.41Å; I488-M491 PolarHBondContact O-N 2.71Å; I488-A492 WeakPolarHBondContact O-CB 3.17Å; I488-A492 PolarHBondContact O-N 3.43Å; I488-L499 HydrophobicContact CG2-CD1 4.47Å; I488-L499 HydrophobicContact CG2-CD2 4.03Å
489I91.9Very high90.5Very high16 Ų1632 Ų328%0.08218%0.181CC..Hα-helixtrans-59.2-46.7176-68.6165.6000110.4I485 G486 M491 A492 I493 L499 F503 M601I485-I489 HydrophobicContact CG2-CD1 3.9Å; I485-I489 HydrophobicContact CG2-CG1 4.45Å; I485-I489 WeakPolarHBondContact O-CG1 3.11Å; I485-I489 PolarHBondContact O-N 2.67Å; G486-I489 PolarHBondContact O-N 2.94Å; I489-M491 VanDerWaalsContact C-N 3.34Å; I489-M491 PolarHBondContact O-N 3.31Å; I489-A492 PolarHBondContact O-N 2.74Å; I489-I493 HydrophobicContact CG2-CD1 3.96Å; I489-I493 WeakPolarHBondContact O-CG1 3.23Å; I489-I493 PolarHBondContact O-N 2.97Å; I489-L499 HydrophobicContact CB-CD1 4.39Å; I489-L499 HydrophobicContact CG1-CD1 3.67Å; I489-F503 HydrophobicContact CD1-CE2 4.01Å; I489-F503 HydrophobicContact CD1-CZ 4.17Å; I489-M601 HydrophobicContact CB-CE 4.3Å; I489-M601 HydrophobicContact CD1-CE 3.84Å; I489-M601 HydrophobicContact CG1-CE 3.89Å; I489-M601 HydrophobicContact CG2-CE 3.43Å; I489-M601 VanDerWaalsContact CG2-CE 3.43Å; I489-M601 HydrophobicContact CG2-CG 4.2Å; I489-M601 HydrophobicContact CG2-SD 3.73Å
490G92.2Very high90.2Very high37 Ų3727.4 Ų27.438%0.38116%0.157SC..Hα-helixtrans-60.1-41.417600000113G486 R487 I488 Y494G486-G490 PolarHBondContact O-N 2.81Å; R487-G490 PolarHBondContact O-N 3.08Å; I488-G490 VanDerWaalsContact C-N 3.34Å; I488-G490 PolarHBondContact O-N 3.42Å; G490-Y494 VanDerWaalsContact O-CB 3.27Å; G490-Y494 WeakPolarHBondContact O-CB 3.44Å; G490-Y494 PolarHBondContact O-N 2.8Å
491M93.7Very high89.3Confident8 Ų826.4 Ų26.44%0.03915%0.15CC..Hα-helixtrans-65.2-43.3174.9-73.5172.56500111.7M393 I408 L416 L420 W439 F440 R487 I488 I489 I493 Y494 H495M393-M491 HydrophobicContact CE-CE 4.05Å; I408-M491 HydrophobicContact CD1-SD 4.11Å; I408-M491 HydrophobicContact CG1-SD 4.21Å; L416-M491 HydrophobicContact CB-CG 4.31Å; L416-M491 HydrophobicContact CB-SD 4.32Å; L416-M491 HydrophobicContact CD1-CG 4.4Å; L416-M491 HydrophobicContact CD1-SD 3.9Å; L416-M491 HydrophobicContact CD2-CE 4.06Å; L416-M491 HydrophobicContact CD2-SD 3.9Å; L416-M491 HydrophobicContact CG-SD 4.27Å; L420-M491 HydrophobicContact CD1-CE 3.94Å; L420-M491 HydrophobicContact CD2-CE 3.91Å; W439-M491 HydrophobicContact CH2-CE 4.17Å; W439-M491 HydrophobicContact CZ3-CE 4.39Å; F440-M491 HydrophobicContact CE1-CB 4.24Å; F440-M491 HydrophobicContact CZ-CB 3.96Å; R487-M491 WeakPolarHBondContact O-CB 3.35Å; R487-M491 VanDerWaalsContact O-CG 3.24Å; R487-M491 WeakPolarHBondContact O-CG 3.47Å; R487-M491 PolarHBondContact O-N 3.13Å; I488-M491 HydrophobicContact CD1-SD 4.5Å; I488-M491 WeakPolarHBondContact O-CB 3.41Å; I488-M491 PolarHBondContact O-N 2.71Å; I489-M491 VanDerWaalsContact C-N 3.34Å; I489-M491 PolarHBondContact O-N 3.31Å; M491-I493 PolarHBondContact O-N 2.76Å; M491-Y494 PolarHBondContact O-N 2.95Å; M491-H495 WeakPolarHBondContact O-CB 3.13Å; M491-H495 PolarHBondContact O-CD2 2.82Å; M491-H495 PolarHBondContact O-N 2.81Å
492A91.5Very high88.6Confident1 Ų127 Ų271%0.00815%0.153CC..Hα-helixtrans-59.3-48177.700000110.6F440 I488 I489 Y494 G496 K497 L499F440-A492 HydrophobicContact CD1-CB 4.15Å; F440-A492 HydrophobicContact CE1-CB 3.79Å; F440-A492 HydrophobicContact CZ-CB 4.39Å; I488-A492 WeakPolarHBondContact O-CB 3.17Å; I488-A492 PolarHBondContact O-N 3.43Å; I489-A492 PolarHBondContact O-N 2.74Å; A492-Y494 PolarHBondContact O-N 2.74Å; A492-G496 CarbonylContact O-C 3.55Å; A492-G496 WeakPolarHBondContact O-CA 3.46Å; A492-G496 PolarHBondContact O-N 2.91Å; A492-K497 CarbonylContact C-O 3.6Å; A492-K497 HydrophobicContact CB-CB 4.46Å; A492-K497 PolarHBondContact O-N 3.19Å; A492-L499 HydrophobicContact CB-CD1 4.17Å; A492-L499 HydrophobicContact CB-CD2 4Å; A492-L499 HydrophobicContact CB-CG 3.86Å
493I89.6Confident88.2Confident38 Ų3825.2 Ų25.220%0.19515%0.145CC..Hα-helixtrans-61.6-46.8176-65.1168.6000111.2L377 I489 M491 G496 L600 M601L377-I493 HydrophobicContact CD2-CG2 4.1Å; I489-I493 HydrophobicContact CG2-CD1 3.96Å; I489-I493 WeakPolarHBondContact O-CG1 3.23Å; I489-I493 PolarHBondContact O-N 2.97Å; M491-I493 PolarHBondContact O-N 2.76Å; I493-G496 PolarHBondContact O-N 2.79Å; I493-L600 HydrophobicContact CG1-CD2 4.48Å; I493-L600 HydrophobicContact CG1-CG 4.39Å; I493-L600 HydrophobicContact CG2-CD2 4.03Å; I493-L600 HydrophobicContact CG2-CG 4.36Å; I493-M601 HydrophobicContact CD1-CG 3.91Å; I493-M601 HydrophobicContact CD1-SD 4.44Å; I493-M601 HydrophobicContact CG1-CG 4.09Å
494Y91.5Very high87.3Confident54 Ų5420.6 Ų20.621%0.21212%0.124CC..Hα-helixtrans-63.6-44.6-178.1-179.6-86.7000112.5L381 P382 R417 G490 M491 A492 G496L381-Y494 HydrophobicContact CB-CD2 4.25Å; L381-Y494 HydrophobicContact CB-CE2 4.15Å; L381-Y494 HydrophobicContact CD1-CD2 3.97Å; L381-Y494 HydrophobicContact CD2-CD2 4.3Å; L381-Y494 HydrophobicContact CG-CD2 4.4Å; P382-Y494 VanDerWaalsContact O-CE2 3.27Å; P382-Y494 WeakPolarHBondContact O-CE2 3.35Å; P382-Y494 PolarHBondContact O-OH 3.07Å; R417-Y494 HydrophobicContact CB-CE1 3.94Å; R417-Y494 HydrophobicContact CB-CE2 4.36Å; R417-Y494 WeakPolarHBondContact CB-OH 3.36Å; R417-Y494 HydrophobicContact CG-CD2 4.27Å; R417-Y494 HydrophobicContact CG-CE1 4.01Å; R417-Y494 HydrophobicContact CG-CE2 3.72Å; R417-Y494 WeakPolarHBondContact O-CE1 3.22Å; R417-Y494 PolarHBondContact O-OH 3.3Å; G490-Y494 VanDerWaalsContact O-CB 3.27Å; G490-Y494 WeakPolarHBondContact O-CB 3.44Å; G490-Y494 PolarHBondContact O-N 2.8Å; M491-Y494 PolarHBondContact O-N 2.95Å; A492-Y494 PolarHBondContact O-N 2.74Å; Y494-G496 VanDerWaalsContact C-N 3.34Å
495H89.4Confident86.3Confident45 Ų4525.2 Ų25.221%0.20814%0.142CC..Hα-helixtrans-87.3-0.8-178.2-69-68.5000113.7L416 N418 M491 K497L416-H495 PolarHBondContact O-NE2 2.68Å; N418-H495 PolarHBondContact O-CE1 3.45Å; N418-H495 VanDerWaalsContact O-CE1 3.23Å; M491-H495 WeakPolarHBondContact O-CB 3.13Å; M491-H495 PolarHBondContact O-CD2 2.82Å; M491-H495 PolarHBondContact O-N 2.81Å; H495-K497 HydrophobicContact CB-CG 4Å
496G86.1Confident85.7Confident23 Ų2325.3 Ų25.324%0.23714%0.142CC..THydrogen-bonded Turntrans64.640.6-178.800000113.1A492 I493 Y494A492-G496 CarbonylContact O-C 3.55Å; A492-G496 WeakPolarHBondContact O-CA 3.46Å; A492-G496 PolarHBondContact O-N 2.91Å; I493-G496 PolarHBondContact O-N 2.79Å; Y494-G496 VanDerWaalsContact C-N 3.34Å
497K87.3Confident85.2Confident27 Ų2724.8 Ų24.812%0.11713%0.129CC..  trans-104.2146.5176.2-52.7-59.6-1781770109.5R437 F440 A492 H495R437-K497 HydrophobicContact CG-CD 3.86Å; F440-K497 HydrophobicContact CD2-CB 3.63Å; F440-K497 HydrophobicContact CD2-CG 3.58Å; F440-K497 HydrophobicContact CE2-CB 3.85Å; F440-K497 HydrophobicContact CE2-CG 3.52Å; F440-K497 HydrophobicContact CG-CB 4.03Å; F440-K497 HydrophobicContact CG-CG 4.46Å; F440-K497 HydrophobicContact CZ-CB 4.39Å; F440-K497 HydrophobicContact CZ-CG 4.33Å; A492-K497 CarbonylContact C-O 3.6Å; A492-K497 HydrophobicContact CB-CB 4.46Å; A492-K497 PolarHBondContact O-N 3.19Å; H495-K497 HydrophobicContact CB-CG 4Å
498L84.7Confident84.7Confident35 Ų3523.1 Ų23.118%0.18312%0.122CC..  trans-95.7141177.1-59.1177.6000109R656L498-R656 HydrophobicContact CB-CB 4.37Å; L498-R656 HydrophobicContact CD1-CB 3.65Å
499L85.5Confident84.1Confident5 Ų524.6 Ų24.63%0.02613%0.129CC..  trans-97.8142.6170-62.3177000109.2F440 I488 I489 A492 A501 M601F440-L499 HydrophobicContact CB-CD2 4.39Å; F440-L499 HydrophobicContact CD1-CD2 3.7Å; F440-L499 HydrophobicContact CE1-CD2 4.5Å; F440-L499 HydrophobicContact CG-CD2 4.48Å; I488-L499 HydrophobicContact CG2-CD1 4.47Å; I488-L499 HydrophobicContact CG2-CD2 4.03Å; I489-L499 HydrophobicContact CB-CD1 4.39Å; I489-L499 HydrophobicContact CG1-CD1 3.67Å; A492-L499 HydrophobicContact CB-CD1 4.17Å; A492-L499 HydrophobicContact CB-CD2 4Å; A492-L499 HydrophobicContact CB-CG 3.86Å; L499-A501 PolarHBondContact O-N 3.4Å; L499-M601 PolarHBondContact N-O 3.21Å
500D81Confident83.5Confident26 Ų2628.9 Ų28.914%0.13915%0.15CC..SBendtrans-91.374.6175.5-160.19.1000110.9F441 S444 H445 S655 R656F441-D500 HydrophobicContact CD2-CB 3.89Å; F441-D500 HydrophobicContact CE2-CB 4.07Å; F441-D500 WeakPolarHBondContact CE2-OD2 3.47Å; S444-D500 WeakPolarHBondContact OG-CA 3.42Å; S444-D500 WeakPolarHBondContact OG-CB 3.14Å; S444-D500 PolarHBondContact OG-N 3.08Å; S444-D500 PolarHBondContact OG-O 3.07Å; H445-D500 IonicContact CE1-OD2 3.1Å; H445-D500 PolarHBondContact CE1-OD2 2.9Å; H445-D500 VanDerWaalsContact CE1-OD2 3.23Å; H445-D500 IonicContact NE2-OD2 3.56Å; D500-S655 PolarHBondContact OD2-OG 3.39Å; D500-R656 IonicContact OD1-CZ 3.64Å; D500-R656 IonicContact OD1-NE 2.76Å; D500-R656 PolarHBondContact OD1-NE 3.1Å; D500-R656 IonicContact OD1-NH2 3.29Å; D500-R656 PolarHBondContact OD1-NH2 2.77Å; D500-R656 IonicContact OD2-NH2 3.44Å
501A73.7Confident83Confident8 Ų829.4 Ų29.47%0.06614%0.143CC..  trans-162.1147.7178.300000111.3F448 L465 L499 C602F448-A501 HydrophobicContact CD2-CB 3.19Å; F448-A501 HydrophobicContact CE1-CB 4.32Å; F448-A501 HydrophobicContact CE2-CB 2.97Å; F448-A501 HydrophobicContact CG-CB 4.03Å; F448-A501 HydrophobicContact CZ-CB 3.6Å; L465-A501 HydrophobicContact CD1-CB 4.37Å; L499-A501 PolarHBondContact O-N 3.4Å; A501-C602 WeakPolarHBondContact O-CB 3.43Å; A501-C602 PolarHBondContact O-SG 2.97Å
502F74.4Confident82.5Confident14 Ų1429.4 Ų29.46%0.06114%0.143CC..EExtended strand (participates in β ladder)trans-121.9120.4173.8-64.5-85.8000108.2T464 L465 E598 C602 Q605T464-F502 CarbonylContact C-O 3.56Å; T464-F502 WeakPolarHBondContact CA-O 3.48Å; T464-F502 HydrophobicContact CG2-CB 4.26Å; L465-F502 PolarHBondContact N-O 2.93Å; F502-E598 HydrophobicContact CD1-CG 4.46Å; F502-E598 WeakPolarHBondContact CD1-OE1 3.42Å; F502-C602 HydrophobicContact CD1-CB 4.17Å; F502-C602 HydrophobicContact CE1-CB 3.88Å; F502-C602 HydrophobicContact CZ-CB 4.42Å; F502-Q605 HydrophobicContact CE1-CB 4.2Å; F502-Q605 HydrophobicContact CE1-CG 4.46Å; F502-Q605 HydrophobicContact CE2-CG 4.09Å; F502-Q605 HydrophobicContact CZ-CB 3.8Å; F502-Q605 HydrophobicContact CZ-CG 3.79Å
503F81.2Confident81.8Confident4 Ų430 Ų302%0.01815%0.149CC..EExtended strand (participates in β ladder)trans-83.6154.9167.7-60.7-71.2000109.5F448 F455 L465 I489 R505 F507 Y508 M601F448-F503 HydrophobicContact CD1-CE1 4.2Å; F448-F503 AromaticContact CE1-CE1 3.36Å; F448-F503 HydrophobicContact CE1-CE1 3.36Å; F448-F503 HydrophobicContact CE1-CE2 4.44Å; F448-F503 AromaticContact CE1-CZ 3.33Å; F448-F503 HydrophobicContact CE1-CZ 3.33Å; F448-F503 HydrophobicContact CZ-CE1 4.01Å; F448-F503 HydrophobicContact CZ-CE2 4.29Å; F448-F503 AromaticContact CZ-CZ 3.51Å; F448-F503 HydrophobicContact CZ-CZ 3.51Å; F455-F503 HydrophobicContact CD1-CE1 4.01Å; F455-F503 HydrophobicContact CE1-CD1 4.3Å; F455-F503 AromaticContact CE1-CE1 3.49Å; F455-F503 HydrophobicContact CE1-CE1 3.49Å; F455-F503 VanDerWaalsContact CE1-CE1 3.49Å; F455-F503 HydrophobicContact CE1-CZ 4.32Å; F455-F503 AromaticContact CZ-CE1 3.89Å; F455-F503 HydrophobicContact CZ-CE1 3.89Å; F455-F503 HydrophobicContact CZ-CZ 4.34Å; L465-F503 HydrophobicContact CB-CD1 4.31Å; L465-F503 CarbonylContact O-C 3.54Å; L465-F503 VanDerWaalsContact O-CA 3.26Å; L465-F503 WeakPolarHBondContact O-CA 3.47Å; I489-F503 HydrophobicContact CD1-CE2 4.01Å; I489-F503 HydrophobicContact CD1-CZ 4.17Å; F503-R505 PolarHBondContact O-N 2.85Å; F503-F507 HydrophobicContact CB-CB 3.78Å; F503-F507 HydrophobicContact CB-CD1 3.36Å; F503-F507 HydrophobicContact CB-CE1 4.27Å; F503-F507 HydrophobicContact CB-CG 3.91Å; F503-F507 AromaticContact CD1-CD1 3.58Å; F503-F507 HydrophobicContact CD1-CD1 3.58Å; F503-F507 AromaticContact CD1-CE1 3.7Å; F503-F507 HydrophobicContact CD1-CE1 3.7Å; F503-F507 HydrophobicContact CD1-CG 4.3Å; F503-F507 AromaticContact CD2-CD1 3.51Å; F503-F507 HydrophobicContact CD2-CD1 3.51Å; F503-F507 AromaticContact CD2-CE1 3.62Å; F503-F507 HydrophobicContact CD2-CE1 3.62Å; F503-F507 HydrophobicContact CE1-CD1 4.18Å; F503-F507 AromaticContact CE1-CE1 3.8Å; F503-F507 HydrophobicContact CE1-CE1 3.8Å; F503-F507 HydrophobicContact CE1-CZ 4.46Å; F503-F507 HydrophobicContact CE2-CD1 4.12Å; F503-F507 AromaticContact CE2-CE1 3.73Å; F503-F507 HydrophobicContact CE2-CE1 3.73Å; F503-F507 HydrophobicContact CG-CB 4.5Å; F503-F507 AromaticContact CG-CD1 3.19Å; F503-F507 HydrophobicContact CG-CD1 3.19Å; F503-F507 AromaticContact CG-CE1 3.6Å; F503-F507 HydrophobicContact CG-CE1 3.6Å; F503-F507 HydrophobicContact CG-CG 4.1Å; F503-F507 HydrophobicContact CZ-CD1 4.41Å; F503-F507 AromaticContact CZ-CE1 3.8Å; F503-F507 HydrophobicContact CZ-CE1 3.8Å; F503-Y508 HydrophobicContact CB-CE1 4.41Å; F503-Y508 HydrophobicContact CB-CE2 3.86Å; F503-Y508 AromaticContact CD2-CE1 3.94Å; F503-Y508 HydrophobicContact CD2-CE1 3.94Å; F503-Y508 AromaticContact CD2-CZ 3.88Å; F503-Y508 PolarHBondContact N-OH 3.47Å; F503-Y508 VanDerWaalsContact N-OH 3.1Å; F503-Y508 WeakPolarHBondContact O-CE2 3.31Å; F503-M601 HydrophobicContact CD2-CE 4.09Å; F503-M601 HydrophobicContact CE2-CE 3.74Å
504I72.3Confident81.3Confident12 Ų1231.3 Ų31.36%0.06215%0.153CC..  trans-52.4142.4166.557.6165.1000109.8L465 Q466 P506 F507 V524L465-I504 PolarHBondContact O-N 2.85Å; Q466-I504 HydrophobicContact CB-CD1 3.54Å; Q466-I504 HydrophobicContact CB-CG1 3.91Å; Q466-I504 HydrophobicContact CB-CG2 4.3Å; I504-P506 VanDerWaalsContact C-N 3.29Å; I504-P506 HydrophobicContact CB-CG 4.41Å; I504-P506 HydrophobicContact CD1-CB 4.15Å; I504-P506 HydrophobicContact CD1-CG 3.97Å; I504-P506 HydrophobicContact CG1-CG 4.33Å; I504-F507 HydrophobicContact CG1-CB 3.9Å; I504-F507 VanDerWaalsContact O-CB 3.24Å; I504-F507 WeakPolarHBondContact O-CB 3.19Å; I504-F507 PolarHBondContact O-N 3.01Å; I504-V524 HydrophobicContact CD1-CG2 3.86Å
505R74.6Confident80.6Confident98 Ų9833.1 Ų33.137%0.3716%0.162SC..Hα-helixtrans-48.9-42177.4-174.1-167-175.993.516.2113.9F503 F507 Y508 K509 A594 N595F503-R505 PolarHBondContact O-N 2.85Å; R505-F507 PolarHBondContact O-N 3.32Å; R505-Y508 PolarHBondContact O-N 3.17Å; R505-K509 PolarHBondContact O-N 3.19Å; R505-K509 VanDerWaalsContact O-N 3.15Å; R505-A594 HydrophobicContact CG-CB 4.11Å; R505-N595 PolarHBondContact NH1-OD1 3.17Å; R505-N595 PolarHBondContact NH2-ND2 2.79Å; R505-N595 VanDerWaalsContact NH2-ND2 3.15Å; R505-N595 PolarHBondContact NH2-OD1 3Å
506P78.3Confident80.2Confident6 Ų631.8 Ų31.84%0.03916%0.156CC..Hα-helixtrans-53.9-36.5173.4-17.517.4000113.5I504 Y508 K509 M510 I516 D520 S523 V524I504-P506 VanDerWaalsContact C-N 3.29Å; I504-P506 HydrophobicContact CB-CG 4.41Å; I504-P506 HydrophobicContact CD1-CB 4.15Å; I504-P506 HydrophobicContact CD1-CG 3.97Å; I504-P506 HydrophobicContact CG1-CG 4.33Å; P506-Y508 VanDerWaalsContact C-N 3.35Å; P506-Y508 PolarHBondContact O-N 3.48Å; P506-K509 CarbonylContact O-C 3.57Å; P506-K509 WeakPolarHBondContact O-CA 3.49Å; P506-K509 VanDerWaalsContact O-CB 3.3Å; P506-K509 WeakPolarHBondContact O-CB 3.41Å; P506-K509 PolarHBondContact O-N 3.34Å; P506-M510 VanDerWaalsContact O-CG 3.29Å; P506-M510 WeakPolarHBondContact O-CG 3.2Å; P506-M510 PolarHBondContact O-N 3.43Å; P506-I516 HydrophobicContact CB-CD1 4.2Å; P506-I516 HydrophobicContact CB-CG2 4.5Å; P506-D520 HydrophobicContact CB-CB 4.44Å; P506-D520 HydrophobicContact CG-CB 4Å; P506-D520 WeakPolarHBondContact CG-O 3.49Å; P506-S523 WeakPolarHBondContact CD-OG 3.37Å; P506-V524 HydrophobicContact CG-CG2 3.61Å
507F82.3Confident80.1Confident28 Ų2833.4 Ų33.412%0.12316%0.162CC..Hα-helixtrans-63.7-40.5-179.3-172.8-111.5000112I467 F503 I504 R505 K509 M510 M511I467-F507 HydrophobicContact CD1-CD2 4.39Å; I467-F507 HydrophobicContact CD1-CE2 3.6Å; I467-F507 HydrophobicContact CD1-CZ 4.42Å; I467-F507 HydrophobicContact CG1-CD2 4.44Å; I467-F507 HydrophobicContact CG1-CE2 3.86Å; F503-F507 HydrophobicContact CB-CB 3.78Å; F503-F507 HydrophobicContact CB-CD1 3.36Å; F503-F507 HydrophobicContact CB-CE1 4.27Å; F503-F507 HydrophobicContact CB-CG 3.91Å; F503-F507 AromaticContact CD1-CD1 3.58Å; F503-F507 HydrophobicContact CD1-CD1 3.58Å; F503-F507 AromaticContact CD1-CE1 3.7Å; F503-F507 HydrophobicContact CD1-CE1 3.7Å; F503-F507 HydrophobicContact CD1-CG 4.3Å; F503-F507 AromaticContact CD2-CD1 3.51Å; F503-F507 HydrophobicContact CD2-CD1 3.51Å; F503-F507 AromaticContact CD2-CE1 3.62Å; F503-F507 HydrophobicContact CD2-CE1 3.62Å; F503-F507 HydrophobicContact CE1-CD1 4.18Å; F503-F507 AromaticContact CE1-CE1 3.8Å; F503-F507 HydrophobicContact CE1-CE1 3.8Å; F503-F507 HydrophobicContact CE1-CZ 4.46Å; F503-F507 HydrophobicContact CE2-CD1 4.12Å; F503-F507 AromaticContact CE2-CE1 3.73Å; F503-F507 HydrophobicContact CE2-CE1 3.73Å; F503-F507 HydrophobicContact CG-CB 4.5Å; F503-F507 AromaticContact CG-CD1 3.19Å; F503-F507 HydrophobicContact CG-CD1 3.19Å; F503-F507 AromaticContact CG-CE1 3.6Å; F503-F507 HydrophobicContact CG-CE1 3.6Å; F503-F507 HydrophobicContact CG-CG 4.1Å; F503-F507 HydrophobicContact CZ-CD1 4.41Å; F503-F507 AromaticContact CZ-CE1 3.8Å; F503-F507 HydrophobicContact CZ-CE1 3.8Å; I504-F507 HydrophobicContact CG1-CB 3.9Å; I504-F507 VanDerWaalsContact O-CB 3.24Å; I504-F507 WeakPolarHBondContact O-CB 3.19Å; I504-F507 PolarHBondContact O-N 3.01Å; R505-F507 PolarHBondContact O-N 3.32Å; F507-K509 VanDerWaalsContact C-N 3.34Å; F507-M510 WeakPolarHBondContact O-CB 3.42Å; F507-M510 PolarHBondContact O-N 3.28Å; F507-M511 HydrophobicContact CD1-CE 3.6Å; F507-M511 HydrophobicContact CD1-SD 4.42Å; F507-M511 HydrophobicContact CE1-CE 3.65Å; F507-M511 HydrophobicContact CE1-CG 4.39Å; F507-M511 HydrophobicContact CE1-SD 3.94Å; F507-M511 HydrophobicContact CZ-SD 4.43Å; F507-M511 PolarHBondContact O-N 3.4Å
508Y84Confident79.7Confident0 Ų033.3 Ų33.30%016%0.162CC..Hα-helixtrans-66.2-37171.8-58.7-70.9000111.8F503 R505 P506 M511 L512 L597 E598 M601 C602F503-Y508 HydrophobicContact CB-CE1 4.41Å; F503-Y508 HydrophobicContact CB-CE2 3.86Å; F503-Y508 AromaticContact CD2-CE1 3.94Å; F503-Y508 HydrophobicContact CD2-CE1 3.94Å; F503-Y508 AromaticContact CD2-CZ 3.88Å; F503-Y508 PolarHBondContact N-OH 3.47Å; F503-Y508 VanDerWaalsContact N-OH 3.1Å; F503-Y508 WeakPolarHBondContact O-CE2 3.31Å; R505-Y508 PolarHBondContact O-N 3.17Å; P506-Y508 VanDerWaalsContact C-N 3.35Å; P506-Y508 PolarHBondContact O-N 3.48Å; Y508-M511 HydrophobicContact CD1-CE 3.38Å; Y508-M511 HydrophobicContact CE1-CE 3.88Å; Y508-M511 HydrophobicContact CG-CE 4.22Å; Y508-M511 PolarHBondContact O-N 3.23Å; Y508-L512 WeakPolarHBondContact O-CB 3.49Å; Y508-L512 WeakPolarHBondContact O-CD1 3.26Å; Y508-L512 WeakPolarHBondContact O-CG 3.35Å; Y508-L512 PolarHBondContact O-N 3.34Å; Y508-L597 HydrophobicContact CD1-CB 4.27Å; Y508-L597 HydrophobicContact CD1-CD2 4.02Å; Y508-L597 HydrophobicContact CD1-CG 3.87Å; Y508-E598 HydrophobicContact CD1-CB 4.27Å; Y508-E598 HydrophobicContact CD2-CB 3.81Å; Y508-E598 HydrophobicContact CD2-CG 4.32Å; Y508-E598 HydrophobicContact CE1-CB 4Å; Y508-E598 HydrophobicContact CE2-CB 3.49Å; Y508-E598 VanDerWaalsContact CE2-CB 3.49Å; Y508-E598 HydrophobicContact CE2-CG 3.57Å; Y508-E598 HydrophobicContact CG-CB 4.19Å; Y508-M601 HydrophobicContact CD1-SD 4.24Å; Y508-M601 HydrophobicContact CE1-CE 4.03Å; Y508-M601 HydrophobicContact CE1-SD 3.84Å; Y508-C602 PolarHBondContact OH-SG 3.27Å
509K80.4Confident79.6Confident31 Ų3137.6 Ų37.614%0.13518%0.18CC..Hα-helixtrans-60.7-45.5171.7-74.3-170.7173.9-174.90111.2R505 P506 F507 L512 G513 K514 I516 D520 A594R505-K509 PolarHBondContact O-N 3.19Å; R505-K509 VanDerWaalsContact O-N 3.15Å; P506-K509 CarbonylContact O-C 3.57Å; P506-K509 WeakPolarHBondContact O-CA 3.49Å; P506-K509 VanDerWaalsContact O-CB 3.3Å; P506-K509 WeakPolarHBondContact O-CB 3.41Å; P506-K509 PolarHBondContact O-N 3.34Å; F507-K509 VanDerWaalsContact C-N 3.34Å; K509-L512 CarbonylContact O-C 2.9Å; K509-L512 VanDerWaalsContact O-C 3.24Å; K509-L512 WeakPolarHBondContact O-CA 3.32Å; K509-L512 PolarHBondContact O-N 3.04Å; K509-G513 CarbonylContact O-C 3.51Å; K509-G513 WeakPolarHBondContact O-CA 3.49Å; K509-G513 PolarHBondContact O-N 2.99Å; K509-K514 HydrophobicContact CB-CB 3.91Å; K509-K514 HydrophobicContact CD-CB 4.39Å; K509-K514 HydrophobicContact CG-CB 4.02Å; K509-K514 PolarHBondContact O-N 3.03Å; K509-I516 HydrophobicContact CB-CD1 3.47Å; K509-I516 VanDerWaalsContact CB-CD1 3.47Å; K509-I516 HydrophobicContact CD-CD1 4.17Å; K509-I516 HydrophobicContact CG-CD1 4.47Å; K509-D520 WeakPolarHBondContact CD-OD1 3.44Å; K509-D520 WeakPolarHBondContact CE-OD1 3.08Å; K509-D520 IonicContact NZ-OD1 2.69Å; K509-D520 PolarHBondContact NZ-OD1 3.43Å; K509-D520 IonicContact NZ-OD2 2.76Å; K509-D520 PolarHBondContact NZ-OD2 2.79Å; K509-A594 HydrophobicContact CG-CB 3.75Å
510M80.1Confident79.4Confident106 Ų10637.4 Ų37.452%0.52218%0.179SC..Hα-helixtrans-60.8-45.7176.6-66.1169.57500111.5P506 F507 L512 G513 I516P506-M510 VanDerWaalsContact O-CG 3.29Å; P506-M510 WeakPolarHBondContact O-CG 3.2Å; P506-M510 PolarHBondContact O-N 3.43Å; F507-M510 WeakPolarHBondContact O-CB 3.42Å; F507-M510 PolarHBondContact O-N 3.28Å; M510-L512 PolarHBondContact O-N 2.84Å; M510-G513 WeakPolarHBondContact O-CA 3.25Å; M510-G513 PolarHBondContact O-N 2.75Å; M510-I516 HydrophobicContact CG-CD1 3.87Å; M510-I516 HydrophobicContact CG-CG1 4.2Å
511M81.5Confident79.2Confident48 Ų4837.5 Ų37.524%0.23618%0.179CC..Hα-helixtrans-61.7-27.6173-76.1-167.2-71.800112.4F507 Y508 G513 R590 L597 M601F507-M511 HydrophobicContact CD1-CE 3.6Å; F507-M511 HydrophobicContact CD1-SD 4.42Å; F507-M511 HydrophobicContact CE1-CE 3.65Å; F507-M511 HydrophobicContact CE1-CG 4.39Å; F507-M511 HydrophobicContact CE1-SD 3.94Å; F507-M511 HydrophobicContact CZ-SD 4.43Å; F507-M511 PolarHBondContact O-N 3.4Å; Y508-M511 HydrophobicContact CD1-CE 3.38Å; Y508-M511 HydrophobicContact CE1-CE 3.88Å; Y508-M511 HydrophobicContact CG-CE 4.22Å; Y508-M511 PolarHBondContact O-N 3.23Å; M511-G513 VanDerWaalsContact C-N 3.33Å; M511-R590 PolarHBondContact O-NE 3.47Å; M511-R590 PolarHBondContact O-NH1 2.89Å; M511-R590 PolarHBondContact O-NH2 3.17Å; M511-L597 HydrophobicContact CB-CD2 3.9Å; M511-L597 HydrophobicContact CE-CD2 3.9Å; M511-M601 HydrophobicContact CE-CE 4.25Å; M511-M601 HydrophobicContact CE-SD 4.01Å
512L82.7Confident79.3Confident8 Ų840.6 Ų40.64%0.04219%0.192CC..THydrogen-bonded Turntrans-91.71.3173.8-65.5165.5000113.3Y508 K509 M510 K514 L589 R590 F592 D593 L597Y508-L512 WeakPolarHBondContact O-CB 3.49Å; Y508-L512 WeakPolarHBondContact O-CD1 3.26Å; Y508-L512 WeakPolarHBondContact O-CG 3.35Å; Y508-L512 PolarHBondContact O-N 3.34Å; K509-L512 CarbonylContact O-C 2.9Å; K509-L512 VanDerWaalsContact O-C 3.24Å; K509-L512 WeakPolarHBondContact O-CA 3.32Å; K509-L512 PolarHBondContact O-N 3.04Å; M510-L512 PolarHBondContact O-N 2.84Å; L512-K514 HydrophobicContact CB-CD 4.49Å; L512-K514 HydrophobicContact CB-CG 4Å; L512-K514 PolarHBondContact O-N 3.3Å; L512-K514 VanDerWaalsContact O-N 3.12Å; L512-L589 CarbonylContact O-C 3.47Å; L512-R590 HydrophobicContact CB-CB 4.2Å; L512-R590 HydrophobicContact CD2-CB 3.88Å; L512-R590 WeakPolarHBondContact O-CB 3.4Å; L512-R590 WeakPolarHBondContact O-CG 3.34Å; L512-R590 PolarHBondContact O-N 3.38Å; L512-F592 VanDerWaalsContact CD1-O 3.24Å; L512-F592 WeakPolarHBondContact CD1-O 3.46Å; L512-F592 HydrophobicContact CD2-CB 4.03Å; L512-F592 WeakPolarHBondContact CD2-O 3.2Å; L512-D593 VanDerWaalsContact CD1-O 3.29Å; L512-D593 WeakPolarHBondContact CD1-O 3.36Å; L512-L597 HydrophobicContact CD1-CB 4.05Å; L512-L597 HydrophobicContact CD1-CD2 4.11Å; L512-L597 HydrophobicContact CD2-CD2 4.02Å; L512-L597 HydrophobicContact CG-CD2 3.76Å
513G76.5Confident78.9Confident13 Ų1341.5 Ų41.513%0.13420%0.2CC..THydrogen-bonded Turntrans45.725.8-164.700000115K509 M510 M511 K515 N587 L588K509-G513 CarbonylContact O-C 3.51Å; K509-G513 WeakPolarHBondContact O-CA 3.49Å; K509-G513 PolarHBondContact O-N 2.99Å; M510-G513 WeakPolarHBondContact O-CA 3.25Å; M510-G513 PolarHBondContact O-N 2.75Å; M511-G513 VanDerWaalsContact C-N 3.33Å; G513-K515 PolarHBondContact O-N 3.39Å; G513-N587 CarbonylContact O-C 3.54Å; G513-L588 VanDerWaalsContact C-C 3.48Å; G513-L588 CarbonylContact C-O 3.48Å; G513-L588 WeakPolarHBondContact CA-O 3.44Å; G513-L588 CarbonylContact O-C 3.6Å; G513-L588 WeakPolarHBondContact O-CA 3.31Å; G513-L588 PolarHBondContact O-N 2.95Å
514K78.8Confident78.3Confident67 Ų6742.6 Ų42.629%0.29121%0.207SC..PPolyproline II helixtrans-64.5140.1170.2-66.2-170175.7-157.80109.3K509 L512 I516 F592K509-K514 HydrophobicContact CB-CB 3.91Å; K509-K514 HydrophobicContact CD-CB 4.39Å; K509-K514 HydrophobicContact CG-CB 4.02Å; K509-K514 PolarHBondContact O-N 3.03Å; L512-K514 HydrophobicContact CB-CD 4.49Å; L512-K514 HydrophobicContact CB-CG 4Å; L512-K514 PolarHBondContact O-N 3.3Å; L512-K514 VanDerWaalsContact O-N 3.12Å; K514-I516 PolarHBondContact O-N 3.05Å; K514-F592 WeakPolarHBondContact CE-O 3.45Å
515K77.2Confident78.2Confident91 Ų9144.5 Ų44.540%0.39622%0.217SC..PPolyproline II helixtrans-53.9130174.1178.8170.2-175.81760109.1G513 E581G513-K515 PolarHBondContact O-N 3.39Å; K515-E581 IonicContact NZ-OE1 2.69Å; K515-E581 PolarHBondContact NZ-OE1 2.95Å
516I82Confident78.2Confident17 Ų1743 Ų439%0.08722%0.217CC..PPolyproline II helixtrans-78.8137.4169.2-49.2-53.8000106.5P506 K509 M510 K514 D520 V584 P585P506-I516 HydrophobicContact CB-CD1 4.2Å; P506-I516 HydrophobicContact CB-CG2 4.5Å; K509-I516 HydrophobicContact CB-CD1 3.47Å; K509-I516 VanDerWaalsContact CB-CD1 3.47Å; K509-I516 HydrophobicContact CD-CD1 4.17Å; K509-I516 HydrophobicContact CG-CD1 4.47Å; M510-I516 HydrophobicContact CG-CD1 3.87Å; M510-I516 HydrophobicContact CG-CG1 4.2Å; K514-I516 PolarHBondContact O-N 3.05Å; I516-D520 HydrophobicContact CG2-CB 3.81Å; I516-V584 HydrophobicContact CB-CG1 3.9Å; I516-V584 HydrophobicContact CG2-CG1 3.82Å; I516-V584 WeakPolarHBondContact O-CG1 3.26Å; I516-P585 WeakPolarHBondContact CB-O 3.18Å
517T82.5Confident78.1Confident57 Ų5750.4 Ų50.435%0.3525%0.251SS..  trans-121.3163.1-17759.30000109.2F519 D520T517-F519 PolarHBondContact O-N 3.4Å; T517-D520 PolarHBondContact N-OD2 3.22Å; T517-D520 VanDerWaalsContact O-CB 3.26Å; T517-D520 WeakPolarHBondContact O-CB 3.39Å; T517-D520 PolarHBondContact O-N 3.3Å; T517-D520 PolarHBondContact OG1-OD2 2.99Å
518L80.9Confident78Confident25 Ų2552.2 Ų52.213%0.13126%0.257CS..Hα-helixtrans-52-40.6176.3176.458.6000112.4D520 M521 Y529 L532 I533 K536 I580L518-D520 PolarHBondContact O-N 2.84Å; L518-D520 VanDerWaalsContact O-N 3.16Å; L518-M521 WeakPolarHBondContact O-CB 3.32Å; L518-M521 PolarHBondContact O-N 3.12Å; L518-Y529 HydrophobicContact CD1-CD2 4.1Å; L518-Y529 HydrophobicContact CD1-CE2 4.43Å; L518-Y529 HydrophobicContact CG-CD2 4.23Å; L518-Y529 HydrophobicContact CG-CE2 4.05Å; L518-Y529 VanDerWaalsContact O-CD2 3.24Å; L518-Y529 WeakPolarHBondContact O-CD2 3.34Å; L518-Y529 WeakPolarHBondContact O-CE2 3.34Å; L518-L532 HydrophobicContact CD1-CB 3.52Å; L518-L532 HydrophobicContact CD1-CD1 3.63Å; L518-L532 HydrophobicContact CD1-CG 4.25Å; L518-I533 HydrophobicContact CD2-CD1 3.64Å; L518-I533 HydrophobicContact CD2-CG1 4.33Å; L518-I533 HydrophobicContact CG-CD1 4.22Å; L518-K536 HydrophobicContact CD2-CD 3.78Å; L518-I580 HydrophobicContact CB-CG2 4.36Å; L518-I580 HydrophobicContact CD1-CG2 4.28Å; L518-I580 HydrophobicContact CD2-CG2 4.14Å; L518-I580 HydrophobicContact CG-CG2 4.49Å
519F81.4Confident77.7Confident125 Ų12553.7 Ų53.755%0.54826%0.263SS..Hα-helixtrans-60.5-24.8177.4-172.1-97.6000113.8T517 M521 E522T517-F519 PolarHBondContact O-N 3.4Å; F519-M521 VanDerWaalsContact C-N 3.27Å; F519-M521 PolarHBondContact O-N 3.39Å; F519-E522 WeakPolarHBondContact CE2-OE2 3.47Å; F519-E522 WeakPolarHBondContact CZ-OE2 3.34Å; F519-E522 WeakPolarHBondContact O-CB 3.29Å; F519-E522 PolarHBondContact O-N 2.81Å
520D81Confident77.8Confident2 Ų256.2 Ų56.21%0.01128%0.278CS..Hα-helixtrans-71.8-25.3176.6-65.8-60.7000112.3P506 K509 I516 T517 L518 E522 S523P506-D520 HydrophobicContact CB-CB 4.44Å; P506-D520 HydrophobicContact CG-CB 4Å; P506-D520 WeakPolarHBondContact CG-O 3.49Å; K509-D520 WeakPolarHBondContact CD-OD1 3.44Å; K509-D520 WeakPolarHBondContact CE-OD1 3.08Å; K509-D520 IonicContact NZ-OD1 2.69Å; K509-D520 PolarHBondContact NZ-OD1 3.43Å; K509-D520 IonicContact NZ-OD2 2.76Å; K509-D520 PolarHBondContact NZ-OD2 2.79Å; I516-D520 HydrophobicContact CG2-CB 3.81Å; T517-D520 PolarHBondContact N-OD2 3.22Å; T517-D520 VanDerWaalsContact O-CB 3.26Å; T517-D520 WeakPolarHBondContact O-CB 3.39Å; T517-D520 PolarHBondContact O-N 3.3Å; T517-D520 PolarHBondContact OG1-OD2 2.99Å; L518-D520 PolarHBondContact O-N 2.84Å; L518-D520 VanDerWaalsContact O-N 3.16Å; D520-E522 PolarHBondContact O-N 3.25Å; D520-S523 PolarHBondContact O-N 3.11Å; D520-S523 PolarHBondContact O-OG 3.46Å
521M77.4Confident78.2Confident28 Ų2853.7 Ų53.714%0.13827%0.271CS..Hα-helixtrans-63.7-27.6176.9-163.962.17400111.8L518 F519 S523 V524 D525 Y528 Y529 L532 V583L518-M521 WeakPolarHBondContact O-CB 3.32Å; L518-M521 PolarHBondContact O-N 3.12Å; F519-M521 VanDerWaalsContact C-N 3.27Å; F519-M521 PolarHBondContact O-N 3.39Å; M521-S523 PolarHBondContact O-N 3.43Å; M521-S523 VanDerWaalsContact O-N 3.08Å; M521-V524 WeakPolarHBondContact O-CB 3.49Å; M521-V524 PolarHBondContact O-N 2.84Å; M521-V524 HydrophobicContact SD-CB 3.84Å; M521-V524 HydrophobicContact SD-CG1 3.98Å; M521-V524 HydrophobicContact SD-CG2 4.28Å; M521-D525 CarbonylContact O-C 3.46Å; M521-D525 PolarHBondContact O-N 3.33Å; M521-D525 VanDerWaalsContact O-O 3.07Å; M521-Y528 HydrophobicContact CE-CD1 4.41Å; M521-Y528 HydrophobicContact CE-CE1 4.36Å; M521-Y528 HydrophobicContact CG-CD1 3.98Å; M521-Y528 HydrophobicContact SD-CD1 4.08Å; M521-Y529 HydrophobicContact CB-CD2 4.23Å; M521-L532 HydrophobicContact CG-CD1 4.39Å; M521-V583 HydrophobicContact CE-CG1 4.41Å
522E76.3Confident78.5Confident72 Ų7251.5 Ų51.534%0.33626%0.26SS..THydrogen-bonded Turntrans-53.7-33.4177.2-172-176.3-147.800112.4T460 F519 D520 N526 Y529T460-E522 VanDerWaalsContact CG2-O 3.3Å; T460-E522 WeakPolarHBondContact CG2-O 3.36Å; F519-E522 WeakPolarHBondContact CE2-OE2 3.47Å; F519-E522 WeakPolarHBondContact CZ-OE2 3.34Å; F519-E522 WeakPolarHBondContact O-CB 3.29Å; F519-E522 PolarHBondContact O-N 2.81Å; D520-E522 PolarHBondContact O-N 3.25Å; E522-N526 WeakPolarHBondContact CG-ND2 3.4Å; E522-Y529 HydrophobicContact CB-CD1 3.75Å; E522-Y529 HydrophobicContact CB-CD2 4.12Å; E522-Y529 HydrophobicContact CB-CE1 3.99Å; E522-Y529 HydrophobicContact CB-CE2 4.34Å; E522-Y529 HydrophobicContact CB-CG 3.81Å; E522-Y529 HydrophobicContact CG-CD1 3.83Å; E522-Y529 HydrophobicContact CG-CE1 3.98Å; E522-Y529 HydrophobicContact CG-CG 4.37Å
523S65.5Low78.8Confident33 Ų3353.1 Ų53.123%0.23127%0.268CS..THydrogen-bonded Turntrans-90.3-8.117964.40000114.9T460 P506 D520 M521T460-S523 PolarHBondContact OG1-O 2.97Å; P506-S523 WeakPolarHBondContact CD-OG 3.37Å; D520-S523 PolarHBondContact O-N 3.11Å; D520-S523 PolarHBondContact O-OG 3.46Å; M521-S523 PolarHBondContact O-N 3.43Å; M521-S523 VanDerWaalsContact O-N 3.08Å
524V69.2Low79.4Confident27 Ų2758.4 Ų58.416%0.16429%0.285CS..THydrogen-bonded Turntrans-93.5-54.6177.8179.80000108A459 Q466 I504 P506 M521A459-V524 PolarHBondContact N-O 3.39Å; A459-V524 VanDerWaalsContact N-O 3.07Å; Q466-V524 VanDerWaalsContact OE1-CG1 3.26Å; I504-V524 HydrophobicContact CD1-CG2 3.86Å; P506-V524 HydrophobicContact CG-CG2 3.61Å; M521-V524 WeakPolarHBondContact O-CB 3.49Å; M521-V524 PolarHBondContact O-N 2.84Å; M521-V524 HydrophobicContact SD-CB 3.84Å; M521-V524 HydrophobicContact SD-CG1 3.98Å; M521-V524 HydrophobicContact SD-CG2 4.28Å
525D70.1Confident79.9Confident53 Ų5355.5 Ų55.528%0.28327%0.273SS..  trans-151.5108.1-179.8-174.9-25.7000108.9A459 M521 E527 Y528 Y529A459-D525 HydrophobicContact CB-CB 4.18Å; M521-D525 CarbonylContact O-C 3.46Å; M521-D525 PolarHBondContact O-N 3.33Å; M521-D525 VanDerWaalsContact O-O 3.07Å; D525-E527 VanDerWaalsContact C-N 3.34Å; D525-E527 PolarHBondContact OD1-N 2.71Å; D525-Y528 PolarHBondContact OD1-N 3.43Å; D525-Y529 VanDerWaalsContact O-CB 3.23Å; D525-Y529 WeakPolarHBondContact O-CB 3.46Å; D525-Y529 PolarHBondContact O-N 2.78Å
526N74.7Confident80.6Confident67 Ų6755.5 Ų55.536%0.35827%0.273SS..Hα-helixtrans-68.9-34.7-178-170.6-97.4000111.7T460 E522 N530T460-N526 HydrophobicContact CG2-CB 3.72Å; T460-N526 VanDerWaalsContact CG2-N 3.26Å; E522-N526 WeakPolarHBondContact CG-ND2 3.4Å; N526-N530 WeakPolarHBondContact O-CB 3.42Å; N526-N530 PolarHBondContact O-N 3.28Å; N526-N530 PolarHBondContact O-ND2 2.81Å; N526-N530 PolarHBondContact OD1-ND2 3.33Å
527E75.5Confident81Confident161 Ų16159.4 Ų59.475%0.75229%0.294SS*.Hα-helixtrans-71.5-45.9-179.5-173.7172.5-175.500110.4D525 Y529 N530 S531D525-E527 VanDerWaalsContact C-N 3.34Å; D525-E527 PolarHBondContact OD1-N 2.71Å; E527-Y529 VanDerWaalsContact C-N 3.34Å; E527-Y529 PolarHBondContact O-N 3.24Å; E527-N530 PolarHBondContact O-N 3.16Å; E527-S531 PolarHBondContact O-N 3.31Å
528Y79.6Confident81.6Confident66 Ų6659.9 Ų59.926%0.25930%0.295SS..Hα-helixtrans-65.3-36.6174.3-168.5-115.8000112.3M521 D525 S531 L532 L549 V583M521-Y528 HydrophobicContact CE-CD1 4.41Å; M521-Y528 HydrophobicContact CE-CE1 4.36Å; M521-Y528 HydrophobicContact CG-CD1 3.98Å; M521-Y528 HydrophobicContact SD-CD1 4.08Å; D525-Y528 PolarHBondContact OD1-N 3.43Å; Y528-S531 PolarHBondContact O-N 2.87Å; Y528-S531 PolarHBondContact O-OG 2.9Å; Y528-L532 HydrophobicContact CD1-CD1 3.95Å; Y528-L532 HydrophobicContact CD1-CG 4.42Å; Y528-L532 HydrophobicContact CE1-CD1 3.66Å; Y528-L532 HydrophobicContact CE1-CG 4.16Å; Y528-L532 WeakPolarHBondContact O-CG 3.25Å; Y528-L532 PolarHBondContact O-N 2.66Å; Y528-L549 WeakPolarHBondContact OH-CD2 3.4Å; Y528-V583 HydrophobicContact CE1-CG1 3.86Å
529Y77.9Confident82Confident30 Ų3063.1 Ų63.112%0.11831%0.312CS..Hα-helixtrans-59.4-47.3170.5168.5-106.1000112.2L518 M521 E522 D525 E527 S531 L532 I533L518-Y529 HydrophobicContact CD1-CD2 4.1Å; L518-Y529 HydrophobicContact CD1-CE2 4.43Å; L518-Y529 HydrophobicContact CG-CD2 4.23Å; L518-Y529 HydrophobicContact CG-CE2 4.05Å; L518-Y529 VanDerWaalsContact O-CD2 3.24Å; L518-Y529 WeakPolarHBondContact O-CD2 3.34Å; L518-Y529 WeakPolarHBondContact O-CE2 3.34Å; M521-Y529 HydrophobicContact CB-CD2 4.23Å; E522-Y529 HydrophobicContact CB-CD1 3.75Å; E522-Y529 HydrophobicContact CB-CD2 4.12Å; E522-Y529 HydrophobicContact CB-CE1 3.99Å; E522-Y529 HydrophobicContact CB-CE2 4.34Å; E522-Y529 HydrophobicContact CB-CG 3.81Å; E522-Y529 HydrophobicContact CG-CD1 3.83Å; E522-Y529 HydrophobicContact CG-CE1 3.98Å; E522-Y529 HydrophobicContact CG-CG 4.37Å; D525-Y529 VanDerWaalsContact O-CB 3.23Å; D525-Y529 WeakPolarHBondContact O-CB 3.46Å; D525-Y529 PolarHBondContact O-N 2.78Å; E527-Y529 VanDerWaalsContact C-N 3.34Å; E527-Y529 PolarHBondContact O-N 3.24Å; Y529-S531 VanDerWaalsContact C-N 3.29Å; Y529-S531 PolarHBondContact O-N 3.37Å; Y529-L532 PolarHBondContact O-N 2.93Å; Y529-I533 HydrophobicContact CD1-CG1 4.37Å; Y529-I533 HydrophobicContact CD2-CG1 4.07Å; Y529-I533 HydrophobicContact CE1-CG1 3.95Å; Y529-I533 HydrophobicContact CE2-CD1 3.76Å; Y529-I533 HydrophobicContact CE2-CG1 3.61Å; Y529-I533 HydrophobicContact CG-CG1 4.44Å; Y529-I533 VanDerWaalsContact O-CG1 3.31Å; Y529-I533 WeakPolarHBondContact O-CG1 3.34Å; Y529-I533 PolarHBondContact O-N 3.4Å
530N83.9Confident82.4Confident84 Ų8457.2 Ų57.245%0.44929%0.286SS..Hα-helixtrans-62.5-36.7178.3-69.3-35.3000111.8N526 E527 I533 Y534N526-N530 WeakPolarHBondContact O-CB 3.42Å; N526-N530 PolarHBondContact O-N 3.28Å; N526-N530 PolarHBondContact O-ND2 2.81Å; N526-N530 PolarHBondContact OD1-ND2 3.33Å; E527-N530 PolarHBondContact O-N 3.16Å; N530-I533 PolarHBondContact O-N 2.99Å; N530-Y534 PolarHBondContact O-N 2.97Å
531S86.7Confident82.6Confident53 Ų5359.8 Ų59.837%0.37131%0.308SS..Hα-helixtrans-66.4-42.1175.680.50000111.9E527 Y528 Y529 Y534 V535E527-S531 PolarHBondContact O-N 3.31Å; Y528-S531 PolarHBondContact O-N 2.87Å; Y528-S531 PolarHBondContact O-OG 2.9Å; Y529-S531 VanDerWaalsContact C-N 3.29Å; Y529-S531 PolarHBondContact O-N 3.37Å; S531-Y534 WeakPolarHBondContact O-CB 2.95Å; S531-Y534 PolarHBondContact O-N 3.24Å; S531-V535 WeakPolarHBondContact O-CG2 3.39Å; S531-V535 PolarHBondContact O-N 3.21Å
532L87.9Confident83.1Confident3 Ų366 Ų662%0.01634%0.341CS..Hα-helixtrans-67.5-35.1175.1-69.4177000112.6L518 M521 Y528 Y529 Y534 V535 K536 Y579 V583L518-L532 HydrophobicContact CD1-CB 3.52Å; L518-L532 HydrophobicContact CD1-CD1 3.63Å; L518-L532 HydrophobicContact CD1-CG 4.25Å; M521-L532 HydrophobicContact CG-CD1 4.39Å; Y528-L532 HydrophobicContact CD1-CD1 3.95Å; Y528-L532 HydrophobicContact CD1-CG 4.42Å; Y528-L532 HydrophobicContact CE1-CD1 3.66Å; Y528-L532 HydrophobicContact CE1-CG 4.16Å; Y528-L532 WeakPolarHBondContact O-CG 3.25Å; Y528-L532 PolarHBondContact O-N 2.66Å; Y529-L532 PolarHBondContact O-N 2.93Å; L532-Y534 VanDerWaalsContact C-N 3.32Å; L532-V535 PolarHBondContact O-N 3.14Å; L532-K536 VanDerWaalsContact O-CB 3.32Å; L532-K536 WeakPolarHBondContact O-CB 3.03Å; L532-K536 PolarHBondContact O-N 3.38Å; L532-Y579 HydrophobicContact CD2-CE1 4.18Å; L532-V583 HydrophobicContact CD1-CG1 4.07Å
533I88.8Confident83.7Confident42 Ų4266 Ų6622%0.21534%0.343CS..Hα-helixtrans-63.7-41.3171.4-70.4-71.1000110.4L518 Y529 N530 K536 D537L518-I533 HydrophobicContact CD2-CD1 3.64Å; L518-I533 HydrophobicContact CD2-CG1 4.33Å; L518-I533 HydrophobicContact CG-CD1 4.22Å; Y529-I533 HydrophobicContact CD1-CG1 4.37Å; Y529-I533 HydrophobicContact CD2-CG1 4.07Å; Y529-I533 HydrophobicContact CE1-CG1 3.95Å; Y529-I533 HydrophobicContact CE2-CD1 3.76Å; Y529-I533 HydrophobicContact CE2-CG1 3.61Å; Y529-I533 HydrophobicContact CG-CG1 4.44Å; Y529-I533 VanDerWaalsContact O-CG1 3.31Å; Y529-I533 WeakPolarHBondContact O-CG1 3.34Å; Y529-I533 PolarHBondContact O-N 3.4Å; N530-I533 PolarHBondContact O-N 2.99Å; I533-K536 WeakPolarHBondContact O-CB 3.44Å; I533-K536 PolarHBondContact O-N 2.96Å; I533-D537 WeakPolarHBondContact O-CB 3.49Å; I533-D537 PolarHBondContact O-N 2.92Å
534Y89.4Confident84.8Confident124 Ų12472.9 Ų72.949%0.48637%0.372SS..Hα-helixtrans-61.5-47.7174.7-176.7-89.2000111.8N530 S531 L532 K536 D537 N538 L543N530-Y534 PolarHBondContact O-N 2.97Å; S531-Y534 WeakPolarHBondContact O-CB 2.95Å; S531-Y534 PolarHBondContact O-N 3.24Å; L532-Y534 VanDerWaalsContact C-N 3.32Å; Y534-K536 VanDerWaalsContact C-N 3.26Å; Y534-K536 PolarHBondContact O-N 2.98Å; Y534-D537 PolarHBondContact O-N 3.02Å; Y534-N538 WeakPolarHBondContact CD2-ND2 3.45Å; Y534-N538 HydrophobicContact CE1-CB 4.22Å; Y534-N538 WeakPolarHBondContact O-CB 3.46Å; Y534-N538 PolarHBondContact O-N 3.24Å; Y534-N538 PolarHBondContact O-ND2 3.33Å; Y534-L543 HydrophobicContact CD1-CD1 4.12Å; Y534-L543 HydrophobicContact CE1-CD1 4.18Å; Y534-L543 HydrophobicContact CE1-CD2 4.28Å
535V90.9Very high85.9Confident6 Ų674 Ų744%0.03638%0.377CS..Hα-helixtrans-56.7-42.2173.8169.80000110.7S531 L532 P540 L543 L545 K576 Y579 I580S531-V535 WeakPolarHBondContact O-CG2 3.39Å; S531-V535 PolarHBondContact O-N 3.21Å; L532-V535 PolarHBondContact O-N 3.14Å; V535-P540 HydrophobicContact CG1-CB 4.1Å; V535-P540 HydrophobicContact CG1-CG 4.38Å; V535-L543 HydrophobicContact CG2-CD1 3.69Å; V535-L545 HydrophobicContact CG2-CD1 3.73Å; V535-K576 HydrophobicContact CG1-CB 4.21Å; V535-K576 WeakPolarHBondContact O-CD 3.36Å; V535-Y579 HydrophobicContact CG1-CD1 4.41Å; V535-I580 HydrophobicContact CG1-CD1 4.35Å; V535-I580 HydrophobicContact CG1-CG1 4.49Å
536K90Very high87Confident90 Ų9073.4 Ų73.439%0.39138%0.375SS..Hα-helixtrans-63.4-44.4179.7-170.5178.3141.3-72.80112.2L518 L532 I533 Y534 K576 I580L518-K536 HydrophobicContact CD2-CD 3.78Å; L532-K536 VanDerWaalsContact O-CB 3.32Å; L532-K536 WeakPolarHBondContact O-CB 3.03Å; L532-K536 PolarHBondContact O-N 3.38Å; I533-K536 WeakPolarHBondContact O-CB 3.44Å; I533-K536 PolarHBondContact O-N 2.96Å; Y534-K536 VanDerWaalsContact C-N 3.26Å; Y534-K536 PolarHBondContact O-N 2.98Å; K536-K576 WeakPolarHBondContact O-CE 3.47Å; K536-K576 PolarHBondContact O-NZ 3.22Å; K536-I580 HydrophobicContact CB-CD1 3.57Å; K536-I580 HydrophobicContact CG-CD1 3.96Å
537D92.3Very high87.9Confident99 Ų9970.3 Ų70.353%0.52936%0.358SS..Hα-helixtrans-93.9-8.2-168.8-65.7-10.6000113.6I533 Y534I533-D537 WeakPolarHBondContact O-CB 3.49Å; I533-D537 PolarHBondContact O-N 2.92Å; Y534-D537 PolarHBondContact O-N 3.02Å
538N93.2Very high88.6Confident68 Ų6863.2 Ų63.236%0.36433%0.327SS..SBendtrans-129171.1179.8-56.9-88.4000111.8Y534 P540 K576Y534-N538 WeakPolarHBondContact CD2-ND2 3.45Å; Y534-N538 HydrophobicContact CE1-CB 4.22Å; Y534-N538 WeakPolarHBondContact O-CB 3.46Å; Y534-N538 PolarHBondContact O-N 3.24Å; Y534-N538 PolarHBondContact O-ND2 3.33Å; N538-P540 WeakPolarHBondContact O-CD 3.45Å; N538-K576 PolarHBondContact O-NZ 3.4Å
539D90.8Very high88.8Confident92 Ų9262.3 Ų62.349%0.49233%0.326SS..  trans-76.1117.6170.6-173.2-11.1000109.7A541 E573D539-A541 VanDerWaalsContact C-N 3.27Å; D539-A541 PolarHBondContact O-N 2.92Å; D539-A541 VanDerWaalsContact OD1-CB 3.25Å; D539-A541 WeakPolarHBondContact OD1-CB 3.31Å; D539-A541 PolarHBondContact OD1-N 3.49Å; D539-E573 VanDerWaalsContact CA-OE2 3.28Å; D539-E573 WeakPolarHBondContact CA-OE2 3.29Å
540P89.6Confident88.9Confident1 Ų166.6 Ų66.61%0.00635%0.351CS..G310 helixtrans-834-178.834.9-35.9000113.7V535 N538 D542 L543 V571 K576V535-P540 HydrophobicContact CG1-CB 4.1Å; V535-P540 HydrophobicContact CG1-CG 4.38Å; N538-P540 WeakPolarHBondContact O-CD 3.45Å; P540-D542 PolarHBondContact O-N 2.93Å; P540-D542 VanDerWaalsContact O-N 3.16Å; P540-L543 HydrophobicContact CB-CD1 3.98Å; P540-L543 WeakPolarHBondContact O-CB 3.2Å; P540-L543 PolarHBondContact O-N 2.95Å; P540-V571 HydrophobicContact CB-CG1 4.31Å; P540-V571 HydrophobicContact CG-CB 4.5Å; P540-V571 HydrophobicContact CG-CG1 3.81Å; P540-K576 HydrophobicContact CG-CB 4.12Å
541A85.6Confident88.2Confident56 Ų5664.9 Ų64.946%0.46334%0.342SS..G310 helixtrans-53.5-37.6-176.700000113.4D539 L543D539-A541 VanDerWaalsContact C-N 3.27Å; D539-A541 PolarHBondContact O-N 2.92Å; D539-A541 VanDerWaalsContact OD1-CB 3.25Å; D539-A541 WeakPolarHBondContact OD1-CB 3.31Å; D539-A541 PolarHBondContact OD1-N 3.49Å; A541-L543 VanDerWaalsContact C-N 3.29Å; A541-L543 PolarHBondContact O-N 3.42Å
542D87Confident87.2Confident159 Ų15966.3 Ų66.385%0.8535%0.352SS*.G310 helixtrans-78.3-9.7179-69.6-21.9000113.6P540 E544P540-D542 PolarHBondContact O-N 2.93Å; P540-D542 VanDerWaalsContact O-N 3.16Å; D542-E544 VanDerWaalsContact C-N 3.31Å
543L88.8Confident85.9Confident72 Ų7267.2 Ų67.238%0.37736%0.356SS..G310 helixtrans-84.6-6.4179.1-58.2176.5000112.8Y534 V535 P540 A541 L545Y534-L543 HydrophobicContact CD1-CD1 4.12Å; Y534-L543 HydrophobicContact CE1-CD1 4.18Å; Y534-L543 HydrophobicContact CE1-CD2 4.28Å; V535-L543 HydrophobicContact CG2-CD1 3.69Å; P540-L543 HydrophobicContact CB-CD1 3.98Å; P540-L543 WeakPolarHBondContact O-CB 3.2Å; P540-L543 PolarHBondContact O-N 2.95Å; A541-L543 VanDerWaalsContact C-N 3.29Å; A541-L543 PolarHBondContact O-N 3.42Å; L543-L545 HydrophobicContact CB-CD1 4.01Å; L543-L545 HydrophobicContact CB-CG 3.77Å; L543-L545 HydrophobicContact CD1-CD1 4.01Å; L543-L545 PolarHBondContact O-N 3.11Å
544E89Confident84.8Confident178 Ų17872.4 Ų72.483%0.83238%0.378SS*.THydrogen-bonded Turntrans51.928.6-179.7-59-172.9162.500113.9D542D542-E544 VanDerWaalsContact C-N 3.31Å
545L92.3Very high83.9Confident51 Ų5170 Ų7027%0.26739%0.39SS..  trans-72.6149180-62.7175000111V535 L543 P570 V571 Y579V535-L545 HydrophobicContact CG2-CD1 3.73Å; L543-L545 HydrophobicContact CB-CD1 4.01Å; L543-L545 HydrophobicContact CB-CG 3.77Å; L543-L545 HydrophobicContact CD1-CD1 4.01Å; L543-L545 PolarHBondContact O-N 3.11Å; L545-P570 WeakPolarHBondContact O-CA 3.48Å; L545-V571 HydrophobicContact CB-CB 3.88Å; L545-V571 HydrophobicContact CB-CG2 3.66Å; L545-V571 PolarHBondContact O-N 3.02Å; L545-Y579 HydrophobicContact CD1-CE1 4.41Å
546T93.7Very high83Confident40 Ų4076.3 Ų76.325%0.24542%0.42CS..BIsolated β-bridgetrans-124.6171168.861.30000109.8S548 V569 Y579T546-S548 PolarHBondContact O-N 3.43Å; T546-S548 PolarHBondContact OG1-OG 3.04Å; T546-V569 CarbonylContact C-O 3.46Å; T546-V569 WeakPolarHBondContact CA-O 3.44Å; T546-V569 WeakPolarHBondContact CB-O 3.42Å; T546-Y579 WeakPolarHBondContact O-CE2 3.18Å
547F93.8Very high82.4Confident1 Ų176.7 Ų76.70%0.00443%0.43CS..SBendtrans-74.248171.8-80.4-113.3000111.8L562 I563 G566 V569 V571 N575 E578 Y579F547-L562 HydrophobicContact CB-CB 4.47Å; F547-L562 WeakPolarHBondContact O-CB 3.46Å; F547-L562 PolarHBondContact O-N 3.09Å; F547-I563 HydrophobicContact CB-CD1 3.85Å; F547-I563 HydrophobicContact CB-CG1 3.75Å; F547-I563 HydrophobicContact CD1-CD1 3.55Å; F547-I563 HydrophobicContact CD1-CG1 3.95Å; F547-I563 HydrophobicContact CD1-CG2 3.97Å; F547-I563 HydrophobicContact CD2-CD1 4.49Å; F547-I563 HydrophobicContact CE1-CD1 4.16Å; F547-I563 HydrophobicContact CG-CD1 3.73Å; F547-I563 HydrophobicContact CG-CG1 4.12Å; F547-G566 CarbonylContact C-O 3.52Å; F547-G566 WeakPolarHBondContact CA-O 3.35Å; F547-G566 PolarHBondContact N-O 2.83Å; F547-G566 CarbonylContact O-C 3.4Å; F547-G566 VanDerWaalsContact O-CA 3.3Å; F547-G566 WeakPolarHBondContact O-CA 3.34Å; F547-V569 HydrophobicContact CB-CB 4.35Å; F547-V569 HydrophobicContact CD2-CB 4.14Å; F547-V569 HydrophobicContact CD2-CG1 3.72Å; F547-V569 HydrophobicContact CE2-CG1 4.09Å; F547-V569 HydrophobicContact CG-CB 4.5Å; F547-V569 HydrophobicContact CG-CG1 4.36Å; F547-V569 PolarHBondContact N-O 3.32Å; F547-V571 HydrophobicContact CD2-CG2 4.03Å; F547-V571 HydrophobicContact CE2-CG2 4.13Å; F547-N575 HydrophobicContact CE2-CB 4.34Å; F547-N575 WeakPolarHBondContact CE2-ND2 3.15Å; F547-N575 HydrophobicContact CZ-CB 4.22Å; F547-E578 HydrophobicContact CE1-CB 4.22Å; F547-E578 HydrophobicContact CE1-CG 4.03Å; F547-E578 HydrophobicContact CZ-CB 4.13Å; F547-E578 HydrophobicContact CZ-CG 4.35Å; F547-Y579 HydrophobicContact CD1-CD2 4.28Å; F547-Y579 HydrophobicContact CD2-CD2 4.24Å; F547-Y579 VanDerWaalsContact CE1-CA 3.45Å; F547-Y579 HydrophobicContact CE2-CD2 4.47Å; F547-Y579 HydrophobicContact CG-CD2 4.15Å
548S90.2Very high81.7Confident13 Ų1376.5 Ų76.59%0.09143%0.425CS..EExtended strand (participates in β ladder)trans-138.5158.2171.768.90000110.1T546 N559 I560T546-S548 PolarHBondContact O-N 3.43Å; T546-S548 PolarHBondContact OG1-OG 3.04Å; S548-N559 VanDerWaalsContact CB-OD1 3.24Å; S548-N559 WeakPolarHBondContact CB-OD1 3.45Å; S548-N559 PolarHBondContact OG-ND2 3.37Å; S548-N559 PolarHBondContact OG-OD1 2.82Å; S548-I560 CarbonylContact C-O 2.88Å; S548-I560 WeakPolarHBondContact CA-O 3.15Å
549L83.2Confident81.3Confident47 Ų4777.1 Ų77.125%0.24643%0.429CS..EExtended strand (participates in β ladder)trans-123.5138.2176.1-62.5177.4000109Y528 N559 I560 L562 V583Y528-L549 WeakPolarHBondContact OH-CD2 3.4Å; L549-N559 CarbonylContact O-C 3.18Å; L549-N559 WeakPolarHBondContact O-CA 3.35Å; L549-I560 PolarHBondContact N-O 3.06Å; L549-I560 PolarHBondContact O-N 2.84Å; L549-L562 HydrophobicContact CD1-CD2 3.64Å; L549-L562 HydrophobicContact CD1-CG 4.45Å; L549-L562 HydrophobicContact CD2-CD1 4.42Å; L549-L562 HydrophobicContact CG-CD1 4.2Å; L549-L562 HydrophobicContact CG-CD2 3.84Å; L549-L562 HydrophobicContact CG-CG 4.13Å; L549-V583 HydrophobicContact CD2-CG2 4.46Å
550D80.2Confident80.9Confident119 Ų11976.3 Ų76.364%0.63642%0.424SS*.EExtended strand (participates in β ladder)trans-91.4114.7170.6-73.7-19.3000109.1T557 N559D550-T557 HydrophobicContact CB-CG2 3.74Å; D550-N559 PolarHBondContact OD1-ND2 2.82Å
551D69.1Low80.9Confident49 Ų4980.6 Ų80.626%0.26244%0.443SS..EExtended strand (participates in β ladder)trans-109.3126179.7-167.47.5000110.1H470 I553 T557 Q558 I560H470-D551 IonicContact CE1-OD2 3.79Å; H470-D551 PolarHBondContact CE1-OD2 3.31Å; H470-D551 VanDerWaalsContact CE1-OD2 3.32Å; H470-D551 IonicContact NE2-OD1 3.25Å; H470-D551 IonicContact NE2-OD2 3.32Å; D551-I553 HydrophobicContact CB-CD1 4.43Å; D551-I553 HydrophobicContact CB-CG1 4.27Å; D551-I553 PolarHBondContact O-N 2.97Å; D551-T557 CarbonylContact O-C 3.55Å; D551-T557 WeakPolarHBondContact O-CA 3.45Å; D551-Q558 PolarHBondContact N-O 3.3Å; D551-Q558 PolarHBondContact O-N 2.81Å; D551-I560 HydrophobicContact CB-CD1 3.65Å; D551-I560 HydrophobicContact CB-CG1 4.31Å
552S65.6Low81Confident82 Ų8279.9 Ų79.957%0.57343%0.432SS*.EExtended strand (participates in β ladder)trans-96.396.5-176.2-172.10000110.5
553I61.3Low81.1Confident22 Ų2274.3 Ų74.311%0.11340%0.401CS..EExtended strand (participates in β ladder)trans-109.9117.2-172.1-44.1-178000109.5H470 D551 G555 E556 Q558H470-I553 HydrophobicContact CB-CG2 4.49Å; H470-I553 WeakPolarHBondContact CE1-CD1 3.43Å; H470-I553 WeakPolarHBondContact CE1-CG1 3.47Å; D551-I553 HydrophobicContact CB-CD1 4.43Å; D551-I553 HydrophobicContact CB-CG1 4.27Å; D551-I553 PolarHBondContact O-N 2.97Å; I553-G555 PolarHBondContact O-N 3.49Å; I553-G555 VanDerWaalsContact O-N 3.09Å; I553-E556 PolarHBondContact N-O 2.87Å; I553-E556 PolarHBondContact O-N 2.89Å; I553-Q558 HydrophobicContact CD1-CG 4.45Å
554F65.1Low81.2Confident152 Ų15276.8 Ų76.867%0.66742%0.422SS*.THydrogen-bonded Turntrans52.427.4-177.9-58.5-71.2000115.3A473A473-F554 HydrophobicContact CB-CE2 3.38Å; A473-F554 HydrophobicContact CB-CZ 3.72Å
555G69.2Low81.3Confident73 Ų7372.8 Ų72.875%0.75341%0.406SS*.THydrogen-bonded Turntrans88.92.4-178.500000114.7I553I553-G555 PolarHBondContact O-N 3.49Å; I553-G555 VanDerWaalsContact O-N 3.09Å
556E72.4Confident81.3Confident139 Ų13970.3 Ų70.365%0.6539%0.393SS*.EExtended strand (participates in β ladder)trans-106.6127169.8-65.4-178.217900109.6I553I553-E556 PolarHBondContact N-O 2.87Å; I553-E556 PolarHBondContact O-N 2.89Å
557T78.2Confident81.3Confident98 Ų9870 Ų7060%0.60140%0.395SS*.EExtended strand (participates in β ladder)trans-80.1121.8172.1-52.80000109.8D550 D551D550-T557 HydrophobicContact CB-CG2 3.74Å; D551-T557 CarbonylContact O-C 3.55Å; D551-T557 WeakPolarHBondContact O-CA 3.45Å
558Q77.5Confident81.3Confident94 Ų9475.5 Ų75.544%0.43942%0.424SS..EExtended strand (participates in β ladder)trans-109133.5173.8-63.4-173.135.500109.7D551 I553D551-Q558 PolarHBondContact N-O 3.3Å; D551-Q558 PolarHBondContact O-N 2.81Å; I553-Q558 HydrophobicContact CD1-CG 4.45Å
559N84.6Confident81.5Confident81 Ų8177 Ų7743%0.43343%0.433SS..EExtended strand (participates in β ladder)trans-90.8117.9174.6-172.6-90.9000109.6S548 L549 D550S548-N559 VanDerWaalsContact CB-OD1 3.24Å; S548-N559 WeakPolarHBondContact CB-OD1 3.45Å; S548-N559 PolarHBondContact OG-ND2 3.37Å; S548-N559 PolarHBondContact OG-OD1 2.82Å; L549-N559 CarbonylContact O-C 3.18Å; L549-N559 WeakPolarHBondContact O-CA 3.35Å; D550-N559 PolarHBondContact OD1-ND2 2.82Å
560I82.4Confident82.1Confident75 Ų7578.3 Ų78.339%0.38544%0.444SS..EExtended strand (participates in β ladder)trans-103.6113.9-178.8-56.9176.9000108.5S548 L549 D551 L562S548-I560 CarbonylContact C-O 2.88Å; S548-I560 WeakPolarHBondContact CA-O 3.15Å; L549-I560 PolarHBondContact N-O 3.06Å; L549-I560 PolarHBondContact O-N 2.84Å; D551-I560 HydrophobicContact CB-CD1 3.65Å; D551-I560 HydrophobicContact CB-CG1 4.31Å; I560-L562 PolarHBondContact O-N 3.09Å
561E90.3Very high82.8Confident91 Ų9172.9 Ų72.943%0.42542%0.415SS..EExtended strand (participates in β ladder)trans-75.4124.7175.3-59.1-168.4162.100111.5I563 N565 G566 A567E561-I563 WeakPolarHBondContact CB-O 3.28Å; E561-N565 WeakPolarHBondContact OE2-CA 3.15Å; E561-N565 PolarHBondContact OE2-N 2.84Å; E561-G566 PolarHBondContact OE2-N 2.69Å; E561-A567 HydrophobicContact CG-CB 4.29Å
562L86.4Confident83.9Confident41 Ų4172.9 Ų72.922%0.21542%0.417CS..SBendtrans-74.9-31-180-65.7177.8000112.8F547 L549 I560 Y579 A582 V583F547-L562 HydrophobicContact CB-CB 4.47Å; F547-L562 WeakPolarHBondContact O-CB 3.46Å; F547-L562 PolarHBondContact O-N 3.09Å; L549-L562 HydrophobicContact CD1-CD2 3.64Å; L549-L562 HydrophobicContact CD1-CG 4.45Å; L549-L562 HydrophobicContact CD2-CD1 4.42Å; L549-L562 HydrophobicContact CG-CD1 4.2Å; L549-L562 HydrophobicContact CG-CD2 3.84Å; L549-L562 HydrophobicContact CG-CG 4.13Å; I560-L562 PolarHBondContact O-N 3.09Å; L562-Y579 HydrophobicContact CD1-CD2 3.78Å; L562-Y579 HydrophobicContact CD1-CE2 3.52Å; L562-A582 HydrophobicContact CB-CB 4.12Å; L562-A582 HydrophobicContact CD1-CB 4.45Å; L562-V583 HydrophobicContact CD1-CG2 3.64Å; L562-V583 HydrophobicContact CD2-CG2 4.5Å
563I89.1Confident85.2Confident42 Ų4273.2 Ų73.222%0.21541%0.409CS..SBendtrans-131.2160.517465179.4000108.2F547 E561 N565 G566 V569F547-I563 HydrophobicContact CB-CD1 3.85Å; F547-I563 HydrophobicContact CB-CG1 3.75Å; F547-I563 HydrophobicContact CD1-CD1 3.55Å; F547-I563 HydrophobicContact CD1-CG1 3.95Å; F547-I563 HydrophobicContact CD1-CG2 3.97Å; F547-I563 HydrophobicContact CD2-CD1 4.49Å; F547-I563 HydrophobicContact CE1-CD1 4.16Å; F547-I563 HydrophobicContact CG-CD1 3.73Å; F547-I563 HydrophobicContact CG-CG1 4.12Å; E561-I563 WeakPolarHBondContact CB-O 3.28Å; I563-N565 PolarHBondContact O-N 3.49Å; I563-G566 WeakPolarHBondContact O-CA 3.23Å; I563-G566 PolarHBondContact O-N 2.79Å; I563-V569 HydrophobicContact CD1-CB 4.38Å; I563-V569 HydrophobicContact CD1-CG1 4.36Å; I563-V569 HydrophobicContact CD1-CG2 4.23Å
564P90.8Very high86.8Confident125 Ų12579.9 Ų79.981%0.81245%0.446SS*.THydrogen-bonded Turntrans-54.3126.9175.3-24.434.1000111.6G566P564-G566 PolarHBondContact O-N 2.79Å
565N91.8Very high88.2Confident93 Ų9374.1 Ų74.150%0.49742%0.422SS..THydrogen-bonded Turntrans63.925.6-176.8-165.151.1000113.7E561 I563 A567 N568E561-N565 WeakPolarHBondContact OE2-CA 3.15Å; E561-N565 PolarHBondContact OE2-N 2.84Å; I563-N565 PolarHBondContact O-N 3.49Å; N565-A567 VanDerWaalsContact C-N 3.29Å; N565-A567 PolarHBondContact O-N 3.46Å; N565-N568 PolarHBondContact O-N 3.43Å; N565-N568 VanDerWaalsContact O-N 3.11Å; N565-N568 PolarHBondContact OD1-ND2 3.47Å
566G93.3Very high89.4Confident0 Ų071.5 Ų71.50%039%0.39CS..G310 helixtrans-64.1-27.5-172.600000114.6F547 E561 I563 P564 N568 V569F547-G566 CarbonylContact C-O 3.52Å; F547-G566 WeakPolarHBondContact CA-O 3.35Å; F547-G566 PolarHBondContact N-O 2.83Å; F547-G566 CarbonylContact O-C 3.4Å; F547-G566 VanDerWaalsContact O-CA 3.3Å; F547-G566 WeakPolarHBondContact O-CA 3.34Å; E561-G566 PolarHBondContact OE2-N 2.69Å; I563-G566 WeakPolarHBondContact O-CA 3.23Å; I563-G566 PolarHBondContact O-N 2.79Å; P564-G566 PolarHBondContact O-N 2.79Å; G566-N568 PolarHBondContact O-N 3.19Å; G566-N568 VanDerWaalsContact O-N 3.11Å; G566-V569 PolarHBondContact O-N 3.08Å
567A92.7Very high90.3Very high33 Ų3372 Ų7227%0.27339%0.392SS..G310 helixtrans-61.5-19.5174.600000113.4E561 N565E561-A567 HydrophobicContact CG-CB 4.29Å; N565-A567 VanDerWaalsContact C-N 3.29Å; N565-A567 PolarHBondContact O-N 3.46Å
568N94.2Very high90.9Very high117 Ų11772.9 Ų72.963%0.62639%0.389SS*.G310 helixtrans-1023.1177-67-55.6000113.4N565 G566 P570N565-N568 PolarHBondContact O-N 3.43Å; N565-N568 VanDerWaalsContact O-N 3.11Å; N565-N568 PolarHBondContact OD1-ND2 3.47Å; G566-N568 PolarHBondContact O-N 3.19Å; G566-N568 VanDerWaalsContact O-N 3.11Å; N568-P570 WeakPolarHBondContact O-CD 3.34Å
569V95Very high91.5Very high44 Ų4468.9 Ų68.927%0.26737%0.37SS..SBendtrans-107.4104.4-179.6-177.70000108.2T546 F547 I563 G566T546-V569 CarbonylContact C-O 3.46Å; T546-V569 WeakPolarHBondContact CA-O 3.44Å; T546-V569 WeakPolarHBondContact CB-O 3.42Å; F547-V569 HydrophobicContact CB-CB 4.35Å; F547-V569 HydrophobicContact CD2-CB 4.14Å; F547-V569 HydrophobicContact CD2-CG1 3.72Å; F547-V569 HydrophobicContact CE2-CG1 4.09Å; F547-V569 HydrophobicContact CG-CB 4.5Å; F547-V569 HydrophobicContact CG-CG1 4.36Å; F547-V569 PolarHBondContact N-O 3.32Å; I563-V569 HydrophobicContact CD1-CB 4.38Å; I563-V569 HydrophobicContact CD1-CG1 4.36Å; I563-V569 HydrophobicContact CD1-CG2 4.23Å; G566-V569 PolarHBondContact O-N 3.08Å
570P94.7Very high91.7Very high75 Ų7565.7 Ų65.749%0.48735%0.353SS..BIsolated β-bridgetrans-67.7146.8177.227.9-33.6000111.1L545 N568 N575L545-P570 WeakPolarHBondContact O-CA 3.48Å; N568-P570 WeakPolarHBondContact O-CD 3.34Å; P570-N575 PolarHBondContact O-ND2 3.34Å
571V94.2Very high91.8Very high4 Ų467.2 Ų67.22%0.02436%0.359CS..  trans-81.3129.1169.3-169.40000108.2P540 L545 F547 N575 K576 Y579P540-V571 HydrophobicContact CB-CG1 4.31Å; P540-V571 HydrophobicContact CG-CB 4.5Å; P540-V571 HydrophobicContact CG-CG1 3.81Å; L545-V571 HydrophobicContact CB-CB 3.88Å; L545-V571 HydrophobicContact CB-CG2 3.66Å; L545-V571 PolarHBondContact O-N 3.02Å; F547-V571 HydrophobicContact CD2-CG2 4.03Å; F547-V571 HydrophobicContact CE2-CG2 4.13Å; V571-N575 WeakPolarHBondContact CA-OD1 3.34Å; V571-K576 HydrophobicContact CG1-CB 4.07Å; V571-Y579 HydrophobicContact CG1-CD1 4.2Å; V571-Y579 HydrophobicContact CG1-CG 4.02Å; V571-Y579 HydrophobicContact CG2-CD1 4.21Å; V571-Y579 HydrophobicContact CG2-CD2 3.45Å; V571-Y579 VanDerWaalsContact CG2-CD2 3.45Å; V571-Y579 HydrophobicContact CG2-CE2 3.85Å; V571-Y579 HydrophobicContact CG2-CG 3.65Å
572T93.4Very high91.5Very high50 Ų5064.8 Ų64.831%0.30735%0.354SS..  trans-133.8165.5-173.762.40000108.6D574 N575 K576T572-D574 PolarHBondContact O-N 3.35Å; T572-D574 VanDerWaalsContact O-N 3.11Å; T572-N575 PolarHBondContact N-OD1 3.3Å; T572-N575 PolarHBondContact O-N 2.95Å; T572-N575 PolarHBondContact O-OD1 2.98Å; T572-N575 VanDerWaalsContact O-OD1 3.09Å; T572-N575 VanDerWaalsContact OG1-CG 3.26Å; T572-N575 PolarHBondContact OG1-N 3.43Å; T572-N575 PolarHBondContact OG1-OD1 3.22Å; T572-K576 WeakPolarHBondContact O-CB 3.46Å; T572-K576 PolarHBondContact O-N 3.35Å
573E92.9Very high91.2Very high88 Ų8863.8 Ų63.841%0.41135%0.349SS..THydrogen-bonded Turntrans-53.2-32.5174.7-173.660.6-166.900113.2D539 K576D539-E573 VanDerWaalsContact CA-OE2 3.28Å; D539-E573 WeakPolarHBondContact CA-OE2 3.29Å; E573-K576 VanDerWaalsContact OE1-CE 3.26Å; E573-K576 WeakPolarHBondContact OE1-CE 3.31Å; E573-K576 IonicContact OE1-NZ 2.79Å; E573-K576 PolarHBondContact OE1-NZ 2.58Å; E573-K576 WeakPolarHBondContact OE2-CE 3.31Å; E573-K576 IonicContact OE2-NZ 3.6Å; E573-K576 PolarHBondContact OE2-NZ 2.88Å
574D94.2Very high90.3Very high163 Ų16362.1 Ų62.187%0.87234%0.341SS*.THydrogen-bonded Turntrans-78.3-28.8-177.5-70.7-31.4000113.9T572T572-D574 PolarHBondContact O-N 3.35Å; T572-D574 VanDerWaalsContact O-N 3.11Å
575N94.5Very high88.7Confident31 Ų3160.2 Ų60.217%0.16633%0.329CS..THydrogen-bonded Turntrans-116.51.8-174.370.21.6000114.3F547 P570 V571 T572 E577 E578 Y579F547-N575 HydrophobicContact CE2-CB 4.34Å; F547-N575 WeakPolarHBondContact CE2-ND2 3.15Å; F547-N575 HydrophobicContact CZ-CB 4.22Å; P570-N575 PolarHBondContact O-ND2 3.34Å; V571-N575 WeakPolarHBondContact CA-OD1 3.34Å; T572-N575 PolarHBondContact N-OD1 3.3Å; T572-N575 PolarHBondContact O-N 2.95Å; T572-N575 PolarHBondContact O-OD1 2.98Å; T572-N575 VanDerWaalsContact O-OD1 3.09Å; T572-N575 VanDerWaalsContact OG1-CG 3.26Å; T572-N575 PolarHBondContact OG1-N 3.43Å; T572-N575 PolarHBondContact OG1-OD1 3.22Å; N575-E577 PolarHBondContact O-N 2.62Å; N575-E578 WeakPolarHBondContact O-CB 3.34Å; N575-E578 PolarHBondContact O-N 3.44Å; N575-Y579 PolarHBondContact O-N 3.4Å
576K93.8Very high86.3Confident18 Ų1859.5 Ų59.58%0.07833%0.331CS..Hα-helixtrans-57.4-32-179.763.6175.4173.3-176.40114.5V535 K536 N538 P540 V571 T572 E573 Y579 I580V535-K576 HydrophobicContact CG1-CB 4.21Å; V535-K576 WeakPolarHBondContact O-CD 3.36Å; K536-K576 WeakPolarHBondContact O-CE 3.47Å; K536-K576 PolarHBondContact O-NZ 3.22Å; N538-K576 PolarHBondContact O-NZ 3.4Å; P540-K576 HydrophobicContact CG-CB 4.12Å; V571-K576 HydrophobicContact CG1-CB 4.07Å; T572-K576 WeakPolarHBondContact O-CB 3.46Å; T572-K576 PolarHBondContact O-N 3.35Å; E573-K576 VanDerWaalsContact OE1-CE 3.26Å; E573-K576 WeakPolarHBondContact OE1-CE 3.31Å; E573-K576 IonicContact OE1-NZ 2.79Å; E573-K576 PolarHBondContact OE1-NZ 2.58Å; E573-K576 WeakPolarHBondContact OE2-CE 3.31Å; E573-K576 IonicContact OE2-NZ 3.6Å; E573-K576 PolarHBondContact OE2-NZ 2.88Å; K576-Y579 WeakPolarHBondContact O-CB 3.28Å; K576-Y579 PolarHBondContact O-N 3.36Å; K576-I580 VanDerWaalsContact O-CG1 3.28Å; K576-I580 WeakPolarHBondContact O-CG1 3.41Å; K576-I580 PolarHBondContact O-N 2.83Å
577E91.2Very high83.6Confident150 Ų15064.4 Ų64.470%0.70136%0.357SS*.Hα-helixtrans-67.5-38.6176.1-67.6-166.8166.500111.6N575 I580 E581N575-E577 PolarHBondContact O-N 2.62Å; E577-I580 PolarHBondContact O-N 3.15Å; E577-E581 WeakPolarHBondContact O-CB 3.27Å; E577-E581 PolarHBondContact O-N 3.32Å
578E91.3Very high80.9Confident116 Ų11669.6 Ų69.654%0.54238%0.38SS..Hα-helixtrans-68.1-38175.8-170.3-179.2179.200110.8F547 N575 E581 A582F547-E578 HydrophobicContact CE1-CB 4.22Å; F547-E578 HydrophobicContact CE1-CG 4.03Å; F547-E578 HydrophobicContact CZ-CB 4.13Å; F547-E578 HydrophobicContact CZ-CG 4.35Å; N575-E578 WeakPolarHBondContact O-CB 3.34Å; N575-E578 PolarHBondContact O-N 3.44Å; E578-E581 PolarHBondContact O-N 3.08Å; E578-A582 VanDerWaalsContact O-CB 3.27Å; E578-A582 WeakPolarHBondContact O-CB 3.32Å; E578-A582 PolarHBondContact O-N 3.06Å
579Y91.1Very high77.8Confident9 Ų971.7 Ų71.74%0.03539%0.39CS..Hα-helixtrans-59.5-51172.4175.4-102.9000111.2L532 V535 L545 T546 F547 L562 V571 N575 K576 E581 A582 V583L532-Y579 HydrophobicContact CD2-CE1 4.18Å; V535-Y579 HydrophobicContact CG1-CD1 4.41Å; L545-Y579 HydrophobicContact CD1-CE1 4.41Å; T546-Y579 WeakPolarHBondContact O-CE2 3.18Å; F547-Y579 HydrophobicContact CD1-CD2 4.28Å; F547-Y579 HydrophobicContact CD2-CD2 4.24Å; F547-Y579 VanDerWaalsContact CE1-CA 3.45Å; F547-Y579 HydrophobicContact CE2-CD2 4.47Å; F547-Y579 HydrophobicContact CG-CD2 4.15Å; L562-Y579 HydrophobicContact CD1-CD2 3.78Å; L562-Y579 HydrophobicContact CD1-CE2 3.52Å; V571-Y579 HydrophobicContact CG1-CD1 4.2Å; V571-Y579 HydrophobicContact CG1-CG 4.02Å; V571-Y579 HydrophobicContact CG2-CD1 4.21Å; V571-Y579 HydrophobicContact CG2-CD2 3.45Å; V571-Y579 VanDerWaalsContact CG2-CD2 3.45Å; V571-Y579 HydrophobicContact CG2-CE2 3.85Å; V571-Y579 HydrophobicContact CG2-CG 3.65Å; N575-Y579 PolarHBondContact O-N 3.4Å; K576-Y579 WeakPolarHBondContact O-CB 3.28Å; K576-Y579 PolarHBondContact O-N 3.36Å; Y579-E581 VanDerWaalsContact C-N 3.33Å; Y579-E581 PolarHBondContact O-N 3.32Å; Y579-A582 PolarHBondContact O-N 3.38Å; Y579-V583 HydrophobicContact CE1-CG2 4.26Å; Y579-V583 HydrophobicContact CE2-CG2 4.36Å; Y579-V583 WeakPolarHBondContact O-CG2 3.33Å; Y579-V583 PolarHBondContact O-N 3.37Å
580I87.4Confident75.6Confident15 Ų1577.5 Ų77.58%0.07741%0.407CS..Hα-helixtrans-61.6-41.2178.5-67.7163.6000111.2L518 V535 K536 K576 E577 V583 V584L518-I580 HydrophobicContact CB-CG2 4.36Å; L518-I580 HydrophobicContact CD1-CG2 4.28Å; L518-I580 HydrophobicContact CD2-CG2 4.14Å; L518-I580 HydrophobicContact CG-CG2 4.49Å; V535-I580 HydrophobicContact CG1-CD1 4.35Å; V535-I580 HydrophobicContact CG1-CG1 4.49Å; K536-I580 HydrophobicContact CB-CD1 3.57Å; K536-I580 HydrophobicContact CG-CD1 3.96Å; K576-I580 VanDerWaalsContact O-CG1 3.28Å; K576-I580 WeakPolarHBondContact O-CG1 3.41Å; K576-I580 PolarHBondContact O-N 2.83Å; E577-I580 PolarHBondContact O-N 3.15Å; I580-V583 PolarHBondContact O-N 3.04Å; I580-V584 WeakPolarHBondContact O-CG2 2.95Å; I580-V584 PolarHBondContact O-N 2.96Å
581E84.7Confident73.6Confident107 Ų10778.6 Ų78.650%0.541%0.409SS..Hα-helixtrans-68.2-36.1176.9-175.2161.3-140.300112.1K515 E577 E578 Y579 V583 V584K515-E581 IonicContact NZ-OE1 2.69Å; K515-E581 PolarHBondContact NZ-OE1 2.95Å; E577-E581 WeakPolarHBondContact O-CB 3.27Å; E577-E581 PolarHBondContact O-N 3.32Å; E578-E581 PolarHBondContact O-N 3.08Å; Y579-E581 VanDerWaalsContact C-N 3.33Å; Y579-E581 PolarHBondContact O-N 3.32Å; E581-V583 VanDerWaalsContact C-N 3.31Å; E581-V583 PolarHBondContact O-N 3.49Å; E581-V584 CarbonylContact O-C 3.59Å; E581-V584 PolarHBondContact O-N 3.46Å; E581-V584 VanDerWaalsContact O-N 3.1Å
582A84Confident71.7Confident40 Ų4079.2 Ų79.233%0.33141%0.411SS..Hα-helixtrans-66.5-33.2175.900000112.5L562 E578 Y579 V584L562-A582 HydrophobicContact CB-CB 4.12Å; L562-A582 HydrophobicContact CD1-CB 4.45Å; E578-A582 VanDerWaalsContact O-CB 3.27Å; E578-A582 WeakPolarHBondContact O-CB 3.32Å; E578-A582 PolarHBondContact O-N 3.06Å; Y579-A582 PolarHBondContact O-N 3.38Å; A582-V584 VanDerWaalsContact C-N 3.27Å; A582-V584 PolarHBondContact O-N 2.99Å
583V80.4Confident70.4Confident19 Ų1978.9 Ų78.912%0.11541%0.407CS..Hα-helixtrans-68.1-26172.2173.20000111.9M521 Y528 L532 L549 L562 Y579 I580 E581M521-V583 HydrophobicContact CE-CG1 4.41Å; Y528-V583 HydrophobicContact CE1-CG1 3.86Å; L532-V583 HydrophobicContact CD1-CG1 4.07Å; L549-V583 HydrophobicContact CD2-CG2 4.46Å; L562-V583 HydrophobicContact CD1-CG2 3.64Å; L562-V583 HydrophobicContact CD2-CG2 4.5Å; Y579-V583 HydrophobicContact CE1-CG2 4.26Å; Y579-V583 HydrophobicContact CE2-CG2 4.36Å; Y579-V583 WeakPolarHBondContact O-CG2 3.33Å; Y579-V583 PolarHBondContact O-N 3.37Å; I580-V583 PolarHBondContact O-N 3.04Å; E581-V583 VanDerWaalsContact C-N 3.31Å; E581-V583 PolarHBondContact O-N 3.49Å
584V70.5Confident69.1Low8 Ų874.8 Ų74.85%0.04839%0.389CS..SBendtrans-110.4108.5-172.7-177.10000112.4I516 I580 E581 A582I516-V584 HydrophobicContact CB-CG1 3.9Å; I516-V584 HydrophobicContact CG2-CG1 3.82Å; I516-V584 WeakPolarHBondContact O-CG1 3.26Å; I580-V584 WeakPolarHBondContact O-CG2 2.95Å; I580-V584 PolarHBondContact O-N 2.96Å; E581-V584 CarbonylContact O-C 3.59Å; E581-V584 PolarHBondContact O-N 3.46Å; E581-V584 VanDerWaalsContact O-N 3.1Å; A582-V584 VanDerWaalsContact C-N 3.27Å; A582-V584 PolarHBondContact O-N 2.99Å
585P56.3Low67.8Low84 Ų8469.9 Ų69.955%0.54536%0.362SS..  trans-70.2153.2-171.124.5-32000115.4I516I516-P585 WeakPolarHBondContact CB-O 3.18Å
586S41.4Very low66.5Low78 Ų7868.7 Ų68.755%0.54536%0.356SS..  trans-123.2131.2-164.6670000117.2
587N37.1Very low65.6Low103 Ų10368.6 Ų68.655%0.55136%0.356SS*.  trans102.2143.9136.1-58.7-29.9000125.4G513G513-N587 CarbonylContact O-C 3.54Å
588L36.2Very low64.7Low142 Ų14263.8 Ų63.874%0.74333%0.333SS*.  trans110.9116.9161.8-72.1161.5000124.3G513G513-L588 VanDerWaalsContact C-C 3.48Å; G513-L588 CarbonylContact C-O 3.48Å; G513-L588 WeakPolarHBondContact CA-O 3.44Å; G513-L588 CarbonylContact O-C 3.6Å; G513-L588 WeakPolarHBondContact O-CA 3.31Å; G513-L588 PolarHBondContact O-N 2.95Å
589L30Very low63.6Low162 Ų16259.1 Ų59.185%0.84831%0.312SS*.  trans-62.5152-166-57.6166.6000121.1L512L512-L589 CarbonylContact O-C 3.47Å
590R49.1Very low62.8Low166 Ų16660 Ų6063%0.62632%0.317SS*.  trans-152.3175.8172.9-68.6-165.4-149.8-174-3.2117.1M511 L512M511-R590 PolarHBondContact O-NE 3.47Å; M511-R590 PolarHBondContact O-NH1 2.89Å; M511-R590 PolarHBondContact O-NH2 3.17Å; L512-R590 HydrophobicContact CB-CB 4.2Å; L512-R590 HydrophobicContact CD2-CB 3.88Å; L512-R590 WeakPolarHBondContact O-CB 3.4Å; L512-R590 WeakPolarHBondContact O-CG 3.34Å; L512-R590 PolarHBondContact O-N 3.38Å
591L52.5Low62.2Low98 Ų9859.4 Ų59.451%0.51331%0.314SS..SBendtrans-69.4-42.5-170.1-170.378.3000116.5Y376Y376-L591 HydrophobicContact CD1-CD2 4.38Å
592F53.9Low61.7Low16 Ų1654.4 Ų54.47%0.0729%0.291CS..SBendtrans-95.6155.3175.1-68.9-78.2000109.8Y370 K373 V374 L377 L512 K514 E596 L600Y370-F592 HydrophobicContact CD2-CD1 4.45Å; Y370-F592 HydrophobicContact CD2-CE1 4.32Å; Y370-F592 HydrophobicContact CE2-CD1 4.28Å; Y370-F592 HydrophobicContact CE2-CE1 4.07Å; K373-F592 HydrophobicContact CB-CD1 4.39Å; K373-F592 HydrophobicContact CB-CE1 3.7Å; K373-F592 HydrophobicContact CB-CZ 4.25Å; K373-F592 HydrophobicContact CD-CD1 4.34Å; K373-F592 HydrophobicContact CD-CE1 4.44Å; V374-F592 HydrophobicContact CG2-CE1 4.49Å; L377-F592 HydrophobicContact CB-CE2 4.35Å; L377-F592 HydrophobicContact CB-CZ 4.08Å; L377-F592 HydrophobicContact CD1-CE2 4.44Å; L377-F592 HydrophobicContact CD2-CE2 3.87Å; L377-F592 HydrophobicContact CD2-CZ 3.91Å; L377-F592 HydrophobicContact CG-CE2 4.44Å; L512-F592 VanDerWaalsContact CD1-O 3.24Å; L512-F592 WeakPolarHBondContact CD1-O 3.46Å; L512-F592 HydrophobicContact CD2-CB 4.03Å; L512-F592 WeakPolarHBondContact CD2-O 3.2Å; K514-F592 WeakPolarHBondContact CE-O 3.45Å; F592-E596 HydrophobicContact CB-CB 4.19Å; F592-E596 HydrophobicContact CD1-CB 3.92Å; F592-L600 HydrophobicContact CE2-CD2 4.23Å; F592-L600 HydrophobicContact CZ-CD2 4.23Å
593D66.8Low61.1Low44 Ų4452.7 Ų52.724%0.23528%0.277CS..  trans-89.1170.4161.473.348.7000112.9L512 N595 E596 L597L512-D593 VanDerWaalsContact CD1-O 3.29Å; L512-D593 WeakPolarHBondContact CD1-O 3.36Å; D593-N595 VanDerWaalsContact C-N 3.29Å; D593-N595 PolarHBondContact O-N 2.96Å; D593-N595 WeakPolarHBondContact OD1-CA 3.44Å; D593-N595 WeakPolarHBondContact OD1-CB 3.49Å; D593-N595 PolarHBondContact OD1-N 3.44Å; D593-E596 PolarHBondContact N-OE2 2.77Å; D593-E596 PolarHBondContact O-N 3.15Å; D593-E596 WeakPolarHBondContact OD1-CG 3.4Å; D593-E596 PolarHBondContact OD1-N 2.95Å; D593-L597 PolarHBondContact O-N 2.66Å
594A65.1Low60.4Low2 Ų252.6 Ų52.62%0.01728%0.276CS..Hα-helixtrans-59.7-40.3-174.600000112.2R505 K509 L597 E598R505-A594 HydrophobicContact CG-CB 4.11Å; K509-A594 HydrophobicContact CG-CB 3.75Å; A594-L597 PolarHBondContact O-N 3.33Å; A594-E598 WeakPolarHBondContact O-CB 3.4Å; A594-E598 PolarHBondContact O-N 2.69Å
595N66.6Low60.2Low60 Ų6056.6 Ų56.632%0.32129%0.294SS..Hα-helixtrans-66.5-45.3176.3-64.8-25.1000110.3R505 D593 L597 E598 L599R505-N595 PolarHBondContact NH1-OD1 3.17Å; R505-N595 PolarHBondContact NH2-ND2 2.79Å; R505-N595 VanDerWaalsContact NH2-ND2 3.15Å; R505-N595 PolarHBondContact NH2-OD1 3Å; D593-N595 VanDerWaalsContact C-N 3.29Å; D593-N595 PolarHBondContact O-N 2.96Å; D593-N595 WeakPolarHBondContact OD1-CA 3.44Å; D593-N595 WeakPolarHBondContact OD1-CB 3.49Å; D593-N595 PolarHBondContact OD1-N 3.44Å; N595-L597 VanDerWaalsContact C-N 3.3Å; N595-L597 PolarHBondContact O-N 2.88Å; N595-E598 PolarHBondContact O-N 3.23Å; N595-L599 WeakPolarHBondContact O-CB 3.28Å; N595-L599 WeakPolarHBondContact O-CD1 3.21Å; N595-L599 WeakPolarHBondContact O-CG 3.28Å; N595-L599 PolarHBondContact O-N 3.38Å
596E68.2Low61.1Low5 Ų558.3 Ų58.32%0.02329%0.293CS..Hα-helixtrans-63.1-36.1179.3-68.6177.7150.900112S367 Y370 K373 F592 D593 L600S367-E596 VanDerWaalsContact CB-OE1 3.31Å; S367-E596 WeakPolarHBondContact CB-OE1 3.45Å; S367-E596 PolarHBondContact OG-OE1 3.07Å; Y370-E596 HydrophobicContact CD2-CB 3.78Å; Y370-E596 HydrophobicContact CD2-CG 3.69Å; Y370-E596 HydrophobicContact CE2-CB 3.87Å; Y370-E596 HydrophobicContact CE2-CG 4.29Å; Y370-E596 WeakPolarHBondContact CE2-O 3.17Å; K373-E596 IonicContact NZ-OE1 2.68Å; K373-E596 PolarHBondContact NZ-OE1 3.34Å; K373-E596 IonicContact NZ-OE2 2.65Å; K373-E596 PolarHBondContact NZ-OE2 3.3Å; F592-E596 HydrophobicContact CB-CB 4.19Å; F592-E596 HydrophobicContact CD1-CB 3.92Å; D593-E596 PolarHBondContact N-OE2 2.77Å; D593-E596 PolarHBondContact O-N 3.15Å; D593-E596 WeakPolarHBondContact OD1-CG 3.4Å; D593-E596 PolarHBondContact OD1-N 2.95Å; E596-L600 VanDerWaalsContact O-CB 3.28Å; E596-L600 WeakPolarHBondContact O-CB 3.36Å; E596-L600 PolarHBondContact O-N 2.8Å
597L74.4Confident63Low17 Ų1754.7 Ų54.79%0.08927%0.267CS..Hα-helixtrans-72.6-43.1176.6-178.460.6000112.1Y508 M511 L512 D593 A594 N595 L599 L600 M601Y508-L597 HydrophobicContact CD1-CB 4.27Å; Y508-L597 HydrophobicContact CD1-CD2 4.02Å; Y508-L597 HydrophobicContact CD1-CG 3.87Å; M511-L597 HydrophobicContact CB-CD2 3.9Å; M511-L597 HydrophobicContact CE-CD2 3.9Å; L512-L597 HydrophobicContact CD1-CB 4.05Å; L512-L597 HydrophobicContact CD1-CD2 4.11Å; L512-L597 HydrophobicContact CD2-CD2 4.02Å; L512-L597 HydrophobicContact CG-CD2 3.76Å; D593-L597 PolarHBondContact O-N 2.66Å; A594-L597 PolarHBondContact O-N 3.33Å; N595-L597 VanDerWaalsContact C-N 3.3Å; N595-L597 PolarHBondContact O-N 2.88Å; L597-L599 VanDerWaalsContact C-N 3.33Å; L597-L599 PolarHBondContact O-N 3.37Å; L597-L600 HydrophobicContact CD1-CD2 4.36Å; L597-L600 WeakPolarHBondContact O-CB 3.21Å; L597-L600 PolarHBondContact O-N 3.35Å; L597-M601 HydrophobicContact CD1-CG 4.3Å; L597-M601 HydrophobicContact CD1-SD 3.94Å; L597-M601 HydrophobicContact CG-SD 3.96Å; L597-M601 WeakPolarHBondContact O-CG 3.49Å; L597-M601 PolarHBondContact O-N 2.81Å
598E72.3Confident65.2Low48 Ų4851.6 Ų51.622%0.22425%0.251CS..Hα-helixtrans-54.2-51.3172179-179.1-174.700110.8F502 Y508 A594 N595 L600 M601 C602F502-E598 HydrophobicContact CD1-CG 4.46Å; F502-E598 WeakPolarHBondContact CD1-OE1 3.42Å; Y508-E598 HydrophobicContact CD1-CB 4.27Å; Y508-E598 HydrophobicContact CD2-CB 3.81Å; Y508-E598 HydrophobicContact CD2-CG 4.32Å; Y508-E598 HydrophobicContact CE1-CB 4Å; Y508-E598 HydrophobicContact CE2-CB 3.49Å; Y508-E598 VanDerWaalsContact CE2-CB 3.49Å; Y508-E598 HydrophobicContact CE2-CG 3.57Å; Y508-E598 HydrophobicContact CG-CB 4.19Å; A594-E598 WeakPolarHBondContact O-CB 3.4Å; A594-E598 PolarHBondContact O-N 2.69Å; N595-E598 PolarHBondContact O-N 3.23Å; E598-L600 VanDerWaalsContact C-N 3.29Å; E598-L600 PolarHBondContact O-N 2.85Å; E598-M601 PolarHBondContact O-N 2.99Å; E598-M601 VanDerWaalsContact O-N 3.09Å; E598-C602 VanDerWaalsContact O-CB 3.29Å; E598-C602 WeakPolarHBondContact O-CB 3.34Å; E598-C602 PolarHBondContact O-N 3.35Å; E598-C602 PolarHBondContact O-SG 3.44Å; E598-C602 VanDerWaalsContact O-SG 3.41Å
599L67.7Low67.7Low19 Ų1944.8 Ų44.810%0.09922%0.215CC..Hα-helixtrans-64.7-33.9179.7-69.3160000113.2Y366 N595 L597 M601 G603 L604 M659Y366-L599 HydrophobicContact CD1-CD1 3.55Å; Y366-L599 HydrophobicContact CE1-CD1 3.1Å; Y366-L599 HydrophobicContact CE1-CD2 3.8Å; Y366-L599 HydrophobicContact CE1-CG 4.07Å; Y366-L599 WeakPolarHBondContact OH-CD2 3.41Å; N595-L599 WeakPolarHBondContact O-CB 3.28Å; N595-L599 WeakPolarHBondContact O-CD1 3.21Å; N595-L599 WeakPolarHBondContact O-CG 3.28Å; N595-L599 PolarHBondContact O-N 3.38Å; L597-L599 VanDerWaalsContact C-N 3.33Å; L597-L599 PolarHBondContact O-N 3.37Å; L599-M601 VanDerWaalsContact C-N 3.28Å; L599-G603 WeakPolarHBondContact O-CA 3.32Å; L599-G603 PolarHBondContact O-N 3.25Å; L599-G603 VanDerWaalsContact O-N 3.15Å; L599-L604 HydrophobicContact CD2-CD2 4.22Å; L599-M659 HydrophobicContact CB-CB 4.49Å; L599-M659 HydrophobicContact CB-CE 4.13Å; L599-M659 HydrophobicContact CB-CG 4.22Å; L599-M659 HydrophobicContact CD1-CE 3.58Å; L599-M659 HydrophobicContact CD1-CG 4.3Å; L599-M659 HydrophobicContact CD2-CG 4.19Å; L599-M659 HydrophobicContact CG-CE 4.44Å; L599-M659 HydrophobicContact CG-CG 4.49Å
600L74.5Confident70.4Confident27 Ų2743 Ų4314%0.14120%0.201CC..Hα-helixtrans-64.8-35.4175.3-178.463.7000111.6Y370 V374 L377 I493 F592 E596 L597 E598Y370-L600 WeakPolarHBondContact OH-CA 3.48Å; Y370-L600 WeakPolarHBondContact OH-CB 3.46Å; Y370-L600 PolarHBondContact OH-N 3.4Å; V374-L600 HydrophobicContact CG2-CD1 4.32Å; L377-L600 HydrophobicContact CD2-CD2 3.88Å; I493-L600 HydrophobicContact CG1-CD2 4.48Å; I493-L600 HydrophobicContact CG1-CG 4.39Å; I493-L600 HydrophobicContact CG2-CD2 4.03Å; I493-L600 HydrophobicContact CG2-CG 4.36Å; F592-L600 HydrophobicContact CE2-CD2 4.23Å; F592-L600 HydrophobicContact CZ-CD2 4.23Å; E596-L600 VanDerWaalsContact O-CB 3.28Å; E596-L600 WeakPolarHBondContact O-CB 3.36Å; E596-L600 PolarHBondContact O-N 2.8Å; L597-L600 HydrophobicContact CD1-CD2 4.36Å; L597-L600 WeakPolarHBondContact O-CB 3.21Å; L597-L600 PolarHBondContact O-N 3.35Å; E598-L600 VanDerWaalsContact C-N 3.29Å; E598-L600 PolarHBondContact O-N 2.85Å
601M75.1Confident72.3Confident3 Ų337 Ų372%0.01518%0.181CC..Hα-helixtrans-88.6-40.7-176.6-71.3174.650.100113.2I489 I493 L499 F503 Y508 M511 L597 E598 L599I489-M601 HydrophobicContact CB-CE 4.3Å; I489-M601 HydrophobicContact CD1-CE 3.84Å; I489-M601 HydrophobicContact CG1-CE 3.89Å; I489-M601 HydrophobicContact CG2-CE 3.43Å; I489-M601 VanDerWaalsContact CG2-CE 3.43Å; I489-M601 HydrophobicContact CG2-CG 4.2Å; I489-M601 HydrophobicContact CG2-SD 3.73Å; I493-M601 HydrophobicContact CD1-CG 3.91Å; I493-M601 HydrophobicContact CD1-SD 4.44Å; I493-M601 HydrophobicContact CG1-CG 4.09Å; L499-M601 PolarHBondContact N-O 3.21Å; F503-M601 HydrophobicContact CD2-CE 4.09Å; F503-M601 HydrophobicContact CE2-CE 3.74Å; Y508-M601 HydrophobicContact CD1-SD 4.24Å; Y508-M601 HydrophobicContact CE1-CE 4.03Å; Y508-M601 HydrophobicContact CE1-SD 3.84Å; M511-M601 HydrophobicContact CE-CE 4.25Å; M511-M601 HydrophobicContact CE-SD 4.01Å; L597-M601 HydrophobicContact CD1-CG 4.3Å; L597-M601 HydrophobicContact CD1-SD 3.94Å; L597-M601 HydrophobicContact CG-SD 3.96Å; L597-M601 WeakPolarHBondContact O-CG 3.49Å; L597-M601 PolarHBondContact O-N 2.81Å; E598-M601 PolarHBondContact O-N 2.99Å; E598-M601 VanDerWaalsContact O-N 3.09Å; L599-M601 VanDerWaalsContact C-N 3.28Å
602C74.3Confident74.2Confident2 Ų232.4 Ų32.41%0.01416%0.157CC..Hα-helixtrans-116.5-21-161-48.20000112.5A501 F502 Y508 E598A501-C602 WeakPolarHBondContact O-CB 3.43Å; A501-C602 PolarHBondContact O-SG 2.97Å; F502-C602 HydrophobicContact CD1-CB 4.17Å; F502-C602 HydrophobicContact CE1-CB 3.88Å; F502-C602 HydrophobicContact CZ-CB 4.42Å; Y508-C602 PolarHBondContact OH-SG 3.27Å; E598-C602 VanDerWaalsContact O-CB 3.29Å; E598-C602 WeakPolarHBondContact O-CB 3.34Å; E598-C602 PolarHBondContact O-N 3.35Å; E598-C602 PolarHBondContact O-SG 3.44Å; E598-C602 VanDerWaalsContact O-SG 3.41Å
603G69.9Low76.1Confident3 Ų334.2 Ų34.23%0.03117%0.165CC..  trans74.8-162-178.700000113.9L599L599-G603 WeakPolarHBondContact O-CA 3.32Å; L599-G603 PolarHBondContact O-N 3.25Å; L599-G603 VanDerWaalsContact O-N 3.15Å
604L65.8Low77.2Confident18 Ų1835.8 Ų35.89%0.09418%0.184CC..BIsolated β-bridgetrans-79.8129178.1-55.1179.6000110.7Y366 L599 V657 M659Y366-L604 HydrophobicContact CE2-CD2 3.85Å; Y366-L604 WeakPolarHBondContact OH-CD2 3.26Å; L599-L604 HydrophobicContact CD2-CD2 4.22Å; L604-V657 HydrophobicContact CB-CB 4.16Å; L604-V657 HydrophobicContact CD1-CB 4.11Å; L604-V657 HydrophobicContact CD1-CG1 4.05Å; L604-V657 HydrophobicContact CG-CB 4.37Å; L604-V657 PolarHBondContact N-O 3.43Å; L604-M659 HydrophobicContact CD2-CG 4.45Å
605Q66.3Low78.5Confident91 Ų9136.5 Ų36.543%0.42519%0.187SC..SBendtrans-75.7-43.6173.3-164.8-173.544.900112F502 N641F502-Q605 HydrophobicContact CE1-CB 4.2Å; F502-Q605 HydrophobicContact CE1-CG 4.46Å; F502-Q605 HydrophobicContact CE2-CG 4.09Å; F502-Q605 HydrophobicContact CZ-CB 3.8Å; F502-Q605 HydrophobicContact CZ-CG 3.79Å; Q605-N641 PolarHBondContact O-ND2 2.88Å
606K75.8Confident79.9Confident121 Ų12134.3 Ų34.353%0.52618%0.176SC..SBendtrans-91.5129.4177.5-68.4-173.3-179.2-179.10111.1N641K606-N641 WeakPolarHBondContact CA-OD1 3.46Å
607I82.5Confident81.1Confident2 Ų237.2 Ų37.21%0.0119%0.191CC..  trans-89.2111.6179.6-63.4177.4000109.3V609 W612 N641 R644 A645 L648 V657 F662I607-V609 PolarHBondContact O-N 2.93Å; I607-W612 HydrophobicContact CG2-CE3 3.68Å; I607-W612 HydrophobicContact CG2-CZ3 4.05Å; I607-N641 PolarHBondContact N-OD1 3.13Å; I607-R644 HydrophobicContact CB-CB 4.34Å; I607-R644 HydrophobicContact CD1-CB 3.84Å; I607-R644 HydrophobicContact CG2-CB 4.44Å; I607-A645 HydrophobicContact CD1-CB 4.02Å; I607-L648 HydrophobicContact CD1-CB 4.46Å; I607-L648 HydrophobicContact CD1-CD2 4.13Å; I607-V657 HydrophobicContact CG1-CG2 3.93Å; I607-V657 HydrophobicContact CG2-CG2 4.44Å; I607-F662 HydrophobicContact CG2-CE2 3.91Å; I607-F662 HydrophobicContact CG2-CZ 3.85Å
608D83.3Confident82.2Confident37 Ų3738.3 Ų38.320%0.19819%0.194CC..  trans-73.9107.7168.8-179.6-15.1000109.6K610 D611 W612D608-K610 VanDerWaalsContact C-N 3.28Å; D608-K610 PolarHBondContact O-N 3.29Å; D608-K610 WeakPolarHBondContact OD1-CA 3.16Å; D608-K610 WeakPolarHBondContact OD1-CB 3.44Å; D608-K610 PolarHBondContact OD1-N 3.44Å; D608-D611 HydrophobicContact CB-CB 3.96Å; D608-D611 PolarHBondContact O-N 3.12Å; D608-D611 PolarHBondContact OD1-N 2.94Å; D608-W612 PolarHBondContact O-N 3.43Å
609V88.7Confident83.3Confident0 Ų039.9 Ų39.90%020%0.2CC..Hα-helixtrans-68.8-29.6-179.1-173.30000111.5F354 A360 I607 W612 K613 W633 I636 L637 R644F354-V609 HydrophobicContact CE1-CG1 3.99Å; A360-V609 PolarHBondContact O-N 2.88Å; I607-V609 PolarHBondContact O-N 2.93Å; V609-W612 PolarHBondContact O-N 3.05Å; V609-K613 VanDerWaalsContact O-CB 3.31Å; V609-K613 WeakPolarHBondContact O-CB 3.31Å; V609-K613 PolarHBondContact O-N 2.78Å; V609-W633 HydrophobicContact CG1-CE3 4.09Å; V609-W633 HydrophobicContact CG1-CZ3 4.33Å; V609-I636 HydrophobicContact CG1-CB 4.34Å; V609-I636 HydrophobicContact CG1-CG2 3.74Å; V609-I636 HydrophobicContact CG2-CG2 4.11Å; V609-L637 HydrophobicContact CB-CD2 4.02Å; V609-L637 HydrophobicContact CG1-CD2 3.86Å; V609-L637 HydrophobicContact CG1-CG 4.18Å; V609-L637 HydrophobicContact CG2-CD2 4.33Å; V609-R644 VanDerWaalsContact CG2-CZ 3.46Å
610K86.4Confident84.4Confident125 Ų12540.9 Ų40.954%0.54322%0.216SC..Hα-helixtrans-69.1-44.6177.8-176.6-178.5179.1177.20110.3D608 K613 A614D608-K610 VanDerWaalsContact C-N 3.28Å; D608-K610 PolarHBondContact O-N 3.29Å; D608-K610 WeakPolarHBondContact OD1-CA 3.16Å; D608-K610 WeakPolarHBondContact OD1-CB 3.44Å; D608-K610 PolarHBondContact OD1-N 3.44Å; K610-K613 PolarHBondContact O-N 2.85Å; K610-A614 VanDerWaalsContact O-CB 3.29Å; K610-A614 WeakPolarHBondContact O-CB 3.48Å; K610-A614 PolarHBondContact O-N 2.78Å
611D88.3Confident85.2Confident40 Ų4043.1 Ų43.121%0.21425%0.245CC..Hα-helixtrans-64.2-41.1174.2-177.158.5000112D608 K613 A614 N615 G661 F662D608-D611 HydrophobicContact CB-CB 3.96Å; D608-D611 PolarHBondContact O-N 3.12Å; D608-D611 PolarHBondContact OD1-N 2.94Å; D611-K613 PolarHBondContact O-N 3.29Å; D611-A614 PolarHBondContact O-N 3.38Å; D611-N615 WeakPolarHBondContact O-CB 3.48Å; D611-N615 PolarHBondContact O-N 2.89Å; D611-N615 PolarHBondContact O-ND2 2.94Å; D611-N615 PolarHBondContact OD1-ND2 3.04Å; D611-G661 WeakPolarHBondContact OD2-CA 3.38Å; D611-F662 WeakPolarHBondContact OD2-CD2 3.31Å; D611-F662 PolarHBondContact OD2-N 2.86Å
612W92.6Very high86.1Confident0 Ų044 Ų440%025%0.249CC..Hα-helixtrans-57-50.6174.4-166.6-4.4000111.6I607 D608 V609 A614 N615 T616 W633 I636 R644 V647 L648 F662 F674I607-W612 HydrophobicContact CG2-CE3 3.68Å; I607-W612 HydrophobicContact CG2-CZ3 4.05Å; D608-W612 PolarHBondContact O-N 3.43Å; V609-W612 PolarHBondContact O-N 3.05Å; W612-A614 PolarHBondContact O-N 2.9Å; W612-N615 PolarHBondContact O-N 3.35Å; W612-T616 PolarHBondContact O-N 2.93Å; W612-T616 PolarHBondContact O-OG1 3.05Å; W612-W633 HydrophobicContact CB-CH2 4.07Å; W612-W633 HydrophobicContact CB-CZ3 3.96Å; W612-W633 AromaticContact CD1-CH2 3.53Å; W612-W633 HydrophobicContact CD2-CH2 4.1Å; W612-W633 AromaticContact CD2-CZ3 3.92Å; W612-W633 HydrophobicContact CD2-CZ3 3.92Å; W612-W633 HydrophobicContact CE3-CZ3 4.4Å; W612-W633 AromaticContact CG-CH2 3.61Å; W612-W633 HydrophobicContact CG-CH2 3.61Å; W612-W633 AromaticContact CG-CZ3 3.7Å; W612-W633 HydrophobicContact CG-CZ3 3.7Å; W612-W633 AromaticContact NE1-CH2 3.9Å; W612-I636 HydrophobicContact CE3-CG2 3.79Å; W612-I636 HydrophobicContact CH2-CD1 4.49Å; W612-I636 HydrophobicContact CZ3-CG2 3.66Å; W612-R644 HydrophobicContact CZ3-CB 4.41Å; W612-V647 HydrophobicContact CH2-CB 4.04Å; W612-V647 HydrophobicContact CH2-CG1 3.77Å; W612-V647 HydrophobicContact CZ2-CG1 4.23Å; W612-L648 HydrophobicContact CH2-CB 4.18Å; W612-L648 HydrophobicContact CZ2-CD1 4.17Å; W612-F662 VanDerWaalsContact CA-CG 3.47Å; W612-F662 HydrophobicContact CB-CD1 4.03Å; W612-F662 HydrophobicContact CB-CD2 3.6Å; W612-F662 HydrophobicContact CB-CE1 3.9Å; W612-F662 HydrophobicContact CB-CE2 3.42Å; W612-F662 VanDerWaalsContact CB-CE2 3.42Å; W612-F662 HydrophobicContact CB-CG 3.92Å; W612-F662 HydrophobicContact CB-CZ 3.58Å; W612-F662 AromaticContact CD1-CD1 3.23Å; W612-F662 AromaticContact CD1-CE1 3.17Å; W612-F662 AromaticContact CD1-CG 3.92Å; W612-F662 AromaticContact CD1-CZ 3.76Å; W612-F662 HydrophobicContact CD2-CD1 4.27Å; W612-F662 AromaticContact CD2-CE1 3.44Å; W612-F662 HydrophobicContact CD2-CE1 3.44Å; W612-F662 VanDerWaalsContact CD2-CE1 3.44Å; W612-F662 HydrophobicContact CD2-CE2 4.15Å; W612-F662 AromaticContact CD2-CZ 3.36Å; W612-F662 HydrophobicContact CD2-CZ 3.36Å; W612-F662 AromaticContact CE2-CE1 3.54Å; W612-F662 AromaticContact CE2-CZ 3.92Å; W612-F662 HydrophobicContact CE3-CE1 4.22Å; W612-F662 HydrophobicContact CE3-CE2 4.47Å; W612-F662 AromaticContact CE3-CZ 3.73Å; W612-F662 HydrophobicContact CE3-CZ 3.73Å; W612-F662 AromaticContact CG-CD1 3.6Å; W612-F662 HydrophobicContact CG-CD1 3.6Å; W612-F662 HydrophobicContact CG-CD2 4.07Å; W612-F662 AromaticContact CG-CE1 3.24Å; W612-F662 HydrophobicContact CG-CE1 3.24Å; W612-F662 AromaticContact CG-CE2 3.72Å; W612-F662 HydrophobicContact CG-CE2 3.72Å; W612-F662 HydrophobicContact CG-CG 4.02Å; W612-F662 AromaticContact CG-CZ 3.3Å; W612-F662 HydrophobicContact CG-CZ 3.3Å; W612-F662 HydrophobicContact CZ2-CE1 4.36Å; W612-F662 HydrophobicContact CZ3-CZ 4.5Å; W612-F662 AromaticContact NE1-CD1 3.78Å; W612-F662 AromaticContact NE1-CE1 3.39Å; W612-F674 AromaticContact CE2-CE2 3.82Å; W612-F674 AromaticContact CE2-CZ 3.97Å; W612-F674 HydrophobicContact CZ2-CD2 4.15Å; W612-F674 HydrophobicContact CZ2-CE1 4.4Å; W612-F674 AromaticContact CZ2-CE2 3.51Å; W612-F674 HydrophobicContact CZ2-CE2 3.51Å; W612-F674 AromaticContact CZ2-CZ 3.67Å; W612-F674 HydrophobicContact CZ2-CZ 3.67Å; W612-F674 AromaticContact NE1-CD1 3.43Å; W612-F674 AromaticContact NE1-CD2 3.33Å; W612-F674 VanDerWaalsContact NE1-CD2 3.33Å; W612-F674 AromaticContact NE1-CE1 3.63Å; W612-F674 AromaticContact NE1-CE2 3.5Å; W612-F674 AromaticContact NE1-CG 3.28Å; W612-F674 VanDerWaalsContact NE1-CG 3.28Å; W612-F674 AromaticContact NE1-CZ 3.67Å
613K92.5Very high86.9Confident54 Ų5444.8 Ų44.824%0.23526%0.256CS..Hα-helixtrans-62.7-43.4179-176.6174.1179.5-173.90112.2F354 V609 K610 D611 N615 T616 W633F354-K613 HydrophobicContact CD1-CD 4.47Å; F354-K613 HydrophobicContact CE1-CD 3.89Å; F354-K613 HydrophobicContact CZ-CD 4.01Å; V609-K613 VanDerWaalsContact O-CB 3.31Å; V609-K613 WeakPolarHBondContact O-CB 3.31Å; V609-K613 PolarHBondContact O-N 2.78Å; K610-K613 PolarHBondContact O-N 2.85Å; D611-K613 PolarHBondContact O-N 3.29Å; K613-N615 VanDerWaalsContact C-N 3.25Å; K613-N615 PolarHBondContact O-N 3.48Å; K613-T616 PolarHBondContact O-N 3.44Å; K613-W633 VanDerWaalsContact CA-CH2 3.44Å; K613-W633 VanDerWaalsContact CA-CZ2 3.48Å; K613-W633 HydrophobicContact CB-CD2 3.89Å; K613-W633 HydrophobicContact CB-CE3 3.9Å; K613-W633 HydrophobicContact CB-CH2 3.99Å; K613-W633 HydrophobicContact CB-CZ2 3.96Å; K613-W633 HydrophobicContact CB-CZ3 3.95Å; K613-W633 HydrophobicContact CD-CB 4.35Å; K613-W633 HydrophobicContact CD-CD2 4.01Å; K613-W633 HydrophobicContact CD-CG 3.87Å; K613-W633 HydrophobicContact CG-CD2 3.82Å; K613-W633 HydrophobicContact CG-CE3 4.34Å; K613-W633 HydrophobicContact CG-CG 4.11Å; K613-W633 HydrophobicContact CG-CZ2 4.15Å
614A90.2Very high87.8Confident77 Ų7749.4 Ų49.464%0.63629%0.286SS*.Hα-helixtrans-65.6-27-18000000113.3K610 D611 W612K610-A614 VanDerWaalsContact O-CB 3.29Å; K610-A614 WeakPolarHBondContact O-CB 3.48Å; K610-A614 PolarHBondContact O-N 2.78Å; D611-A614 PolarHBondContact O-N 3.38Å; W612-A614 PolarHBondContact O-N 2.9Å
615N92.5Very high88.7Confident17 Ų1752 Ų529%0.09131%0.306CS..THydrogen-bonded Turntrans-106.116.5-178.7-70-73.4000114.3D611 W612 K613 F662 R663 K673D611-N615 WeakPolarHBondContact O-CB 3.48Å; D611-N615 PolarHBondContact O-N 2.89Å; D611-N615 PolarHBondContact O-ND2 2.94Å; D611-N615 PolarHBondContact OD1-ND2 3.04Å; W612-N615 PolarHBondContact O-N 3.35Å; K613-N615 VanDerWaalsContact C-N 3.25Å; K613-N615 PolarHBondContact O-N 3.48Å; N615-F662 HydrophobicContact CB-CB 3.65Å; N615-R663 WeakPolarHBondContact OD1-CA 3.46Å; N615-R663 VanDerWaalsContact OD1-CB 3.26Å; N615-R663 WeakPolarHBondContact OD1-CB 3.39Å; N615-K673 WeakPolarHBondContact O-CD 3.18Å
616T95.5Very high89.9Confident14 Ų1448.9 Ų48.99%0.08629%0.294CS..  trans-92.3135.8175.5-67.10000112.3W612 K613 Y618 W633 F674 I676W612-T616 PolarHBondContact O-N 2.93Å; W612-T616 PolarHBondContact O-OG1 3.05Å; K613-T616 PolarHBondContact O-N 3.44Å; T616-Y618 HydrophobicContact CG2-CD1 4.26Å; T616-Y618 HydrophobicContact CG2-CE1 3.71Å; T616-Y618 HydrophobicContact CG2-CE2 4.37Å; T616-W633 HydrophobicContact CG2-CZ2 3.99Å; T616-W633 WeakPolarHBondContact OG1-CH2 3.36Å; T616-W633 WeakPolarHBondContact OG1-CZ2 3.48Å; T616-F674 CarbonylContact C-O 3.56Å; T616-F674 WeakPolarHBondContact CA-O 3.1Å; T616-F674 HydrophobicContact CG2-CD1 3.78Å; T616-F674 HydrophobicContact CG2-CE1 4.46Å; T616-F674 WeakPolarHBondContact OG1-CD1 3.42Å; T616-I676 HydrophobicContact CG2-CD1 4.08Å; T616-I676 HydrophobicContact CG2-CG1 3.9Å
617I95.3Very high90.5Very high67 Ų6745.7 Ų45.734%0.34428%0.281SS..EExtended strand (participates in β ladder)trans-96139172.1-60.4178.1000109.3K619 K673 F674 T675 I676I617-K619 HydrophobicContact CG2-CG 4.25Å; I617-K673 HydrophobicContact CD1-CB 3.81Å; I617-K673 HydrophobicContact CD1-CD 4.06Å; I617-K673 HydrophobicContact CD1-CG 4.37Å; I617-K673 HydrophobicContact CG1-CB 3.98Å; I617-K673 HydrophobicContact CG1-CD 4.06Å; I617-F674 PolarHBondContact N-O 3.1Å; I617-T675 HydrophobicContact CB-CG2 4.41Å; I617-T675 HydrophobicContact CG2-CG2 4.43Å; I617-T675 CarbonylContact O-C 3.54Å; I617-T675 VanDerWaalsContact O-CA 3.23Å; I617-T675 WeakPolarHBondContact O-CA 3.36Å; I617-I676 PolarHBondContact O-N 2.94Å
618Y96.6Very high91Very high39 Ų3946.1 Ų46.115%0.15328%0.284CS..EExtended strand (participates in β ladder)trans-110.9137.3175.7-51.5-81.9000110.8T616 Y622 P624 V629 W633 I676T616-Y618 HydrophobicContact CG2-CD1 4.26Å; T616-Y618 HydrophobicContact CG2-CE1 3.71Å; T616-Y618 HydrophobicContact CG2-CE2 4.37Å; Y618-Y622 WeakPolarHBondContact CB-O 3.47Å; Y618-P624 HydrophobicContact CD2-CG 3.99Å; Y618-P624 HydrophobicContact CE2-CB 4.4Å; Y618-P624 HydrophobicContact CE2-CG 3.88Å; Y618-V629 HydrophobicContact CD1-CG1 3.95Å; Y618-V629 HydrophobicContact CD1-CG2 3.71Å; Y618-V629 HydrophobicContact CE1-CB 4.26Å; Y618-V629 HydrophobicContact CE1-CG1 3.3Å; Y618-V629 HydrophobicContact CE1-CG2 3.9Å; Y618-W633 AromaticContact CE1-NE1 3.96Å; Y618-W633 AromaticContact CZ-NE1 3.81Å; Y618-W633 PolarHBondContact OH-NE1 3.27Å; Y618-I676 CarbonylContact C-O 3.54Å; Y618-I676 WeakPolarHBondContact CA-O 3.28Å; Y618-I676 HydrophobicContact CD1-CB 4.12Å; Y618-I676 HydrophobicContact CE1-CB 4.49Å; Y618-I676 HydrophobicContact CE1-CD1 4.07Å
619K95Very high91.5Very high81 Ų8144.4 Ų44.435%0.35227%0.274SS..EExtended strand (participates in β ladder)trans-136.9172.6-178.3-67.2-171.9-178-179.40111.9I617 G621 Y622 T675 I676 E677 R678I617-K619 HydrophobicContact CG2-CG 4.25Å; K619-G621 VanDerWaalsContact C-N 3.29Å; K619-G621 PolarHBondContact O-N 3.38Å; K619-Y622 WeakPolarHBondContact O-CB 3.4Å; K619-Y622 PolarHBondContact O-N 3.14Å; K619-T675 HydrophobicContact CD-CG2 3.87Å; K619-T675 HydrophobicContact CG-CG2 4.01Å; K619-I676 PolarHBondContact N-O 3.16Å; K619-E677 HydrophobicContact CB-CB 3.98Å; K619-E677 HydrophobicContact CB-CG 3.72Å; K619-R678 PolarHBondContact O-N 3.05Å
620G91.9Very high91.6Very high41 Ų4146 Ų4642%0.42328%0.282SS..THydrogen-bonded Turntrans69.424.5178.100000114.1Y622 R678G620-Y622 VanDerWaalsContact C-N 3.32Å; G620-R678 WeakPolarHBondContact O-CB 3.47Å; G620-R678 WeakPolarHBondContact O-CD 3.45Å
621G90.8Very high91.8Very high74 Ų7440.4 Ų40.476%0.76326%0.258SS*.THydrogen-bonded Turntrans84.81.4-175.400000114.3K619K619-G621 VanDerWaalsContact C-N 3.29Å; K619-G621 PolarHBondContact O-N 3.38Å
622Y94.9Very high92.2Very high22 Ų2238.5 Ų38.59%0.08625%0.248CC..  trans-75.9145.2164.7-68-16.3000111.4Y618 K619 G620 V628 V629 I676 R678 L697 P698 P699Y618-Y622 WeakPolarHBondContact CB-O 3.47Å; K619-Y622 WeakPolarHBondContact O-CB 3.4Å; K619-Y622 PolarHBondContact O-N 3.14Å; G620-Y622 VanDerWaalsContact C-N 3.32Å; Y622-V628 HydrophobicContact CD1-CG1 3.8Å; Y622-V628 HydrophobicContact CD2-CG1 4.33Å; Y622-V628 HydrophobicContact CE1-CG1 3.38Å; Y622-V628 HydrophobicContact CE2-CG1 3.93Å; Y622-V628 HydrophobicContact CG-CG1 4.27Å; Y622-V628 VanDerWaalsContact CZ-CG1 3.43Å; Y622-V629 HydrophobicContact CD2-CG2 4.45Å; Y622-V629 HydrophobicContact CG-CG2 4.3Å; Y622-I676 HydrophobicContact CD2-CG2 4.09Å; Y622-I676 HydrophobicContact CE2-CG2 4.48Å; Y622-R678 HydrophobicContact CD1-CB 3.88Å; Y622-R678 HydrophobicContact CD1-CG 4.36Å; Y622-R678 HydrophobicContact CD2-CB 3.88Å; Y622-R678 HydrophobicContact CE1-CB 3.58Å; Y622-R678 HydrophobicContact CE1-CG 3.63Å; Y622-R678 HydrophobicContact CE2-CB 3.6Å; Y622-R678 HydrophobicContact CE2-CG 4.18Å; Y622-R678 HydrophobicContact CG-CB 4.02Å; Y622-R678 VanDerWaalsContact CZ-CB 3.44Å; Y622-L697 HydrophobicContact CE2-CB 4.18Å; Y622-L697 WeakPolarHBondContact CE2-O 3.33Å; Y622-L697 PolarHBondContact OH-O 2.94Å; Y622-P698 VanDerWaalsContact OH-C 3.3Å; Y622-P698 PolarHBondContact OH-O 3.43Å; Y622-P699 WeakPolarHBondContact OH-CA 3.17Å
623G90.3Very high92.2Very high17 Ų1738.6 Ų38.618%0.17525%0.248CC..  trans-144.3175.6171.200000110.7S625 S626G623-S625 PolarHBondContact O-N 2.75Å; G623-S626 PolarHBondContact N-OG 3.34Å; G623-S626 WeakPolarHBondContact O-CB 3.21Å; G623-S626 PolarHBondContact O-N 3.5Å; G623-S626 PolarHBondContact O-OG 2.71Å
624P88.2Confident92Very high101 Ų10137.2 Ų37.266%0.65624%0.242SC*.THydrogen-bonded Turntrans-55.9-27.9-178.4-24.833.2000114.1Y618Y618-P624 HydrophobicContact CD2-CG 3.99Å; Y618-P624 HydrophobicContact CE2-CB 4.4Å; Y618-P624 HydrophobicContact CE2-CG 3.88Å
625S85.5Confident92.1Very high72 Ų7233.5 Ų33.550%0.50321%0.212SC..THydrogen-bonded Turntrans-91.82.4179.865.40000114.4G623G623-S625 PolarHBondContact O-N 2.75Å
626S90.8Very high92Very high25 Ų2532.7 Ų32.718%0.17521%0.207CC..  trans-71.5134.4178.3-62.20000110.3G623 V628 V629 H630G623-S626 PolarHBondContact N-OG 3.34Å; G623-S626 WeakPolarHBondContact O-CB 3.21Å; G623-S626 PolarHBondContact O-N 3.5Å; G623-S626 PolarHBondContact O-OG 2.71Å; S626-V628 VanDerWaalsContact C-N 3.28Å; S626-V628 PolarHBondContact O-N 2.72Å; S626-V629 WeakPolarHBondContact O-CA 3.47Å; S626-V629 WeakPolarHBondContact O-CB 3.44Å; S626-V629 PolarHBondContact O-N 3.17Å; S626-H630 PolarHBondContact O-N 2.88Å
627Q88.8Confident91.7Very high55 Ų5532.3 Ų32.326%0.25720%0.204SC..Hα-helixtrans-57.4-40.5-177.8-173.458.846.600112.8V629 H630 N631Q627-V629 VanDerWaalsContact C-N 3.32Å; Q627-V629 PolarHBondContact O-N 3.39Å; Q627-H630 WeakPolarHBondContact O-CB 3.26Å; Q627-H630 PolarHBondContact O-N 3.41Å; Q627-N631 PolarHBondContact NE2-OD1 3.43Å; Q627-N631 WeakPolarHBondContact O-CB 3.48Å; Q627-N631 VanDerWaalsContact O-CG 3.25Å; Q627-N631 PolarHBondContact O-N 2.91Å
628V93.1Very high91.3Very high11 Ų1130.5 Ų30.57%0.06720%0.198CC..Hα-helixtrans-62.7-36.4175.565.20000112.6Y622 S626 N631 F632 L697 L706Y622-V628 HydrophobicContact CD1-CG1 3.8Å; Y622-V628 HydrophobicContact CD2-CG1 4.33Å; Y622-V628 HydrophobicContact CE1-CG1 3.38Å; Y622-V628 HydrophobicContact CE2-CG1 3.93Å; Y622-V628 HydrophobicContact CG-CG1 4.27Å; Y622-V628 VanDerWaalsContact CZ-CG1 3.43Å; S626-V628 VanDerWaalsContact C-N 3.28Å; S626-V628 PolarHBondContact O-N 2.72Å; V628-N631 PolarHBondContact O-N 3.49Å; V628-F632 WeakPolarHBondContact O-CB 3.39Å; V628-F632 PolarHBondContact O-N 3.32Å; V628-L697 HydrophobicContact CG2-CD2 3.85Å; V628-L697 HydrophobicContact CG2-CG 4.14Å; V628-L706 HydrophobicContact CG2-CD1 3.98Å; V628-L706 WeakPolarHBondContact O-CD1 3.1Å
629V93.7Very high90.8Very high0 Ų029.3 Ų29.30%019%0.194CC..Hα-helixtrans-70-41.2175.5168.80000110.5Y618 Y622 S626 Q627 F632 W633Y618-V629 HydrophobicContact CD1-CG1 3.95Å; Y618-V629 HydrophobicContact CD1-CG2 3.71Å; Y618-V629 HydrophobicContact CE1-CB 4.26Å; Y618-V629 HydrophobicContact CE1-CG1 3.3Å; Y618-V629 HydrophobicContact CE1-CG2 3.9Å; Y622-V629 HydrophobicContact CD2-CG2 4.45Å; Y622-V629 HydrophobicContact CG-CG2 4.3Å; S626-V629 WeakPolarHBondContact O-CA 3.47Å; S626-V629 WeakPolarHBondContact O-CB 3.44Å; S626-V629 PolarHBondContact O-N 3.17Å; Q627-V629 VanDerWaalsContact C-N 3.32Å; Q627-V629 PolarHBondContact O-N 3.39Å; V629-F632 WeakPolarHBondContact O-CB 3.45Å; V629-F632 PolarHBondContact O-N 2.8Å; V629-W633 PolarHBondContact O-N 2.88Å
630H90.7Very high90.1Very high33 Ų3330.1 Ų30.115%0.15320%0.201CC..Hα-helixtrans-59.5-47.7172.7179.8-83.6000111.1F339 S626 Q627 F632 W633 K634F339-H630 AromaticContact CE2-NE2 3.92Å; S626-H630 PolarHBondContact O-N 2.88Å; Q627-H630 WeakPolarHBondContact O-CB 3.26Å; Q627-H630 PolarHBondContact O-N 3.41Å; H630-F632 VanDerWaalsContact C-N 3.32Å; H630-F632 PolarHBondContact O-N 3.32Å; H630-W633 PolarHBondContact O-N 3.21Å; H630-K634 VanDerWaalsContact O-CB 3.3Å; H630-K634 WeakPolarHBondContact O-CB 3.09Å; H630-K634 PolarHBondContact O-N 2.58Å
631N91.1Very high89.5Confident9 Ų930.5 Ų30.55%0.04819%0.194CC..Hα-helixtrans-62.8-37.6177.4-69.4-10.5000112.2Q627 V628 K634 C635 F703 L706Q627-N631 PolarHBondContact NE2-OD1 3.43Å; Q627-N631 WeakPolarHBondContact O-CB 3.48Å; Q627-N631 VanDerWaalsContact O-CG 3.25Å; Q627-N631 PolarHBondContact O-N 2.91Å; V628-N631 PolarHBondContact O-N 3.49Å; N631-K634 WeakPolarHBondContact O-CB 3.3Å; N631-K634 PolarHBondContact O-N 2.76Å; N631-C635 WeakPolarHBondContact O-CB 3.22Å; N631-C635 PolarHBondContact O-N 3.05Å; N631-F703 PolarHBondContact ND2-N 2.89Å; N631-L706 HydrophobicContact CB-CD1 3.94Å
632F95.4Very high88.8Confident0 Ų032.2 Ų32.20%018%0.182CC..Hα-helixtrans-59.7-53.4173.9175.2-96.3000111.1V628 V629 H630 K634 C635 I636 F674 I676 L695 L697 L706 L710V628-F632 WeakPolarHBondContact O-CB 3.39Å; V628-F632 PolarHBondContact O-N 3.32Å; V629-F632 WeakPolarHBondContact O-CB 3.45Å; V629-F632 PolarHBondContact O-N 2.8Å; H630-F632 VanDerWaalsContact C-N 3.32Å; H630-F632 PolarHBondContact O-N 3.32Å; F632-K634 VanDerWaalsContact C-N 3.31Å; F632-K634 PolarHBondContact O-N 2.85Å; F632-C635 WeakPolarHBondContact O-CA 3.3Å; F632-C635 WeakPolarHBondContact O-CB 3.25Å; F632-C635 PolarHBondContact O-N 2.84Å; F632-I636 HydrophobicContact CD1-CG1 4.16Å; F632-I636 HydrophobicContact CE1-CD1 4.31Å; F632-I636 HydrophobicContact CE1-CG1 3.69Å; F632-I636 HydrophobicContact CE2-CD1 3.99Å; F632-I636 HydrophobicContact CE2-CG1 4.19Å; F632-I636 HydrophobicContact CZ-CD1 3.8Å; F632-I636 HydrophobicContact CZ-CG1 3.71Å; F632-I636 WeakPolarHBondContact O-CG1 3.27Å; F632-I636 PolarHBondContact O-N 2.88Å; F632-F674 HydrophobicContact CE1-CE1 4.43Å; F632-F674 HydrophobicContact CZ-CE1 4.26Å; F632-F674 HydrophobicContact CZ-CZ 4.23Å; F632-I676 HydrophobicContact CD1-CD1 3.44Å; F632-I676 VanDerWaalsContact CD1-CD1 3.44Å; F632-I676 HydrophobicContact CE1-CD1 3.47Å; F632-I676 VanDerWaalsContact CE1-CD1 3.47Å; F632-I676 HydrophobicContact CG-CD1 4.01Å; F632-I676 HydrophobicContact CZ-CD1 4.05Å; F632-L695 HydrophobicContact CD2-CD2 4.03Å; F632-L695 HydrophobicContact CE2-CD2 3.42Å; F632-L695 VanDerWaalsContact CE2-CD2 3.42Å; F632-L695 HydrophobicContact CZ-CD2 4Å; F632-L697 HydrophobicContact CB-CD2 4.11Å; F632-L697 HydrophobicContact CD2-CD2 4.22Å; F632-L697 HydrophobicContact CG-CD2 4.36Å; F632-L706 HydrophobicContact CB-CD1 4.12Å; F632-L710 HydrophobicContact CD2-CD2 4.39Å; F632-L710 HydrophobicContact CE2-CD2 4.19Å
633W94Very high88.2Confident2 Ų232.7 Ų32.71%0.00819%0.186CC..Hα-helixtrans-67.3-32.6-179.6-69.4115.9000113.3F354 V609 W612 K613 T616 Y618 V629 H630 C635 I636 L637 I676F354-W633 HydrophobicContact CZ-CB 3.86Å; V609-W633 HydrophobicContact CG1-CE3 4.09Å; V609-W633 HydrophobicContact CG1-CZ3 4.33Å; W612-W633 HydrophobicContact CB-CH2 4.07Å; W612-W633 HydrophobicContact CB-CZ3 3.96Å; W612-W633 AromaticContact CD1-CH2 3.53Å; W612-W633 HydrophobicContact CD2-CH2 4.1Å; W612-W633 AromaticContact CD2-CZ3 3.92Å; W612-W633 HydrophobicContact CD2-CZ3 3.92Å; W612-W633 HydrophobicContact CE3-CZ3 4.4Å; W612-W633 AromaticContact CG-CH2 3.61Å; W612-W633 HydrophobicContact CG-CH2 3.61Å; W612-W633 AromaticContact CG-CZ3 3.7Å; W612-W633 HydrophobicContact CG-CZ3 3.7Å; W612-W633 AromaticContact NE1-CH2 3.9Å; K613-W633 VanDerWaalsContact CA-CH2 3.44Å; K613-W633 VanDerWaalsContact CA-CZ2 3.48Å; K613-W633 HydrophobicContact CB-CD2 3.89Å; K613-W633 HydrophobicContact CB-CE3 3.9Å; K613-W633 HydrophobicContact CB-CH2 3.99Å; K613-W633 HydrophobicContact CB-CZ2 3.96Å; K613-W633 HydrophobicContact CB-CZ3 3.95Å; K613-W633 HydrophobicContact CD-CB 4.35Å; K613-W633 HydrophobicContact CD-CD2 4.01Å; K613-W633 HydrophobicContact CD-CG 3.87Å; K613-W633 HydrophobicContact CG-CD2 3.82Å; K613-W633 HydrophobicContact CG-CE3 4.34Å; K613-W633 HydrophobicContact CG-CG 4.11Å; K613-W633 HydrophobicContact CG-CZ2 4.15Å; T616-W633 HydrophobicContact CG2-CZ2 3.99Å; T616-W633 WeakPolarHBondContact OG1-CH2 3.36Å; T616-W633 WeakPolarHBondContact OG1-CZ2 3.48Å; Y618-W633 AromaticContact CE1-NE1 3.96Å; Y618-W633 AromaticContact CZ-NE1 3.81Å; Y618-W633 PolarHBondContact OH-NE1 3.27Å; V629-W633 PolarHBondContact O-N 2.88Å; H630-W633 PolarHBondContact O-N 3.21Å; W633-C635 VanDerWaalsContact C-N 3.26Å; W633-C635 PolarHBondContact O-N 3.11Å; W633-I636 HydrophobicContact CE3-CB 4.25Å; W633-I636 HydrophobicContact CE3-CG1 4.28Å; W633-I636 HydrophobicContact CE3-CG2 4.5Å; W633-I636 HydrophobicContact CZ3-CG1 4.49Å; W633-I636 HydrophobicContact CZ3-CG2 4.47Å; W633-I636 PolarHBondContact O-N 2.74Å; W633-L637 PolarHBondContact O-N 3.04Å; W633-I676 HydrophobicContact CZ2-CD1 4.44Å
634K88.4Confident88.1Confident24 Ų2432.9 Ų32.910%0.10418%0.181CC..Hα-helixtrans-57-43.1168.7-171.9179.9176.7-179.50110.5D318 I320 H630 N631 F632 L637 S638 F703D318-K634 IonicContact OD1-NZ 2.76Å; D318-K634 PolarHBondContact OD1-NZ 3.39Å; D318-K634 IonicContact OD2-NZ 2.97Å; I320-K634 HydrophobicContact CD1-CB 4.36Å; I320-K634 HydrophobicContact CD1-CD 4.28Å; I320-K634 HydrophobicContact CD1-CG 3.33Å; I320-K634 WeakPolarHBondContact CD1-O 3.4Å; H630-K634 VanDerWaalsContact O-CB 3.3Å; H630-K634 WeakPolarHBondContact O-CB 3.09Å; H630-K634 PolarHBondContact O-N 2.58Å; N631-K634 WeakPolarHBondContact O-CB 3.3Å; N631-K634 PolarHBondContact O-N 2.76Å; F632-K634 VanDerWaalsContact C-N 3.31Å; F632-K634 PolarHBondContact O-N 2.85Å; K634-L637 PolarHBondContact O-N 3.22Å; K634-S638 PolarHBondContact O-N 3.06Å; K634-F703 HydrophobicContact CB-CD2 4.06Å; K634-F703 HydrophobicContact CB-CE2 4.02Å; K634-F703 HydrophobicContact CD-CD2 3.68Å; K634-F703 HydrophobicContact CD-CE2 3.94Å; K634-F703 HydrophobicContact CD-CG 4.07Å; K634-F703 HydrophobicContact CG-CD2 3.84Å; K634-F703 HydrophobicContact CG-CE2 3.66Å; K634-F703 HydrophobicContact CG-CZ 4.38Å
635C91.4Very high87.8Confident0 Ų028.6 Ų28.60%015%0.154CC..Hα-helixtrans-64.6-48177.2-165.50000111.6N631 F632 W633 L637 S638 F639 F703 L706N631-C635 WeakPolarHBondContact O-CB 3.22Å; N631-C635 PolarHBondContact O-N 3.05Å; F632-C635 WeakPolarHBondContact O-CA 3.3Å; F632-C635 WeakPolarHBondContact O-CB 3.25Å; F632-C635 PolarHBondContact O-N 2.84Å; W633-C635 VanDerWaalsContact C-N 3.26Å; W633-C635 PolarHBondContact O-N 3.11Å; C635-L637 VanDerWaalsContact C-N 3.32Å; C635-L637 PolarHBondContact O-N 3.1Å; C635-S638 PolarHBondContact O-N 2.9Å; C635-S638 VanDerWaalsContact O-N 3.08Å; C635-S638 PolarHBondContact O-OG 2.8Å; C635-F639 WeakPolarHBondContact O-CG 3.21Å; C635-F639 PolarHBondContact O-N 2.99Å; C635-F639 WeakPolarHBondContact SG-CZ 3.01Å; C635-F703 HydrophobicContact CB-CE2 4.01Å; C635-L706 HydrophobicContact CB-CD2 3.95Å
636I91.9Very high87.6Confident0 Ų029.6 Ų29.60%015%0.147CC..Hα-helixtrans-62.1-38.5178.7-57.2-49.9000112.1V609 W612 F632 W633 S638 F639 R644 V647V609-I636 HydrophobicContact CG1-CB 4.34Å; V609-I636 HydrophobicContact CG1-CG2 3.74Å; V609-I636 HydrophobicContact CG2-CG2 4.11Å; W612-I636 HydrophobicContact CE3-CG2 3.79Å; W612-I636 HydrophobicContact CH2-CD1 4.49Å; W612-I636 HydrophobicContact CZ3-CG2 3.66Å; F632-I636 HydrophobicContact CD1-CG1 4.16Å; F632-I636 HydrophobicContact CE1-CD1 4.31Å; F632-I636 HydrophobicContact CE1-CG1 3.69Å; F632-I636 HydrophobicContact CE2-CD1 3.99Å; F632-I636 HydrophobicContact CE2-CG1 4.19Å; F632-I636 HydrophobicContact CZ-CD1 3.8Å; F632-I636 HydrophobicContact CZ-CG1 3.71Å; F632-I636 WeakPolarHBondContact O-CG1 3.27Å; F632-I636 PolarHBondContact O-N 2.88Å; W633-I636 HydrophobicContact CE3-CB 4.25Å; W633-I636 HydrophobicContact CE3-CG1 4.28Å; W633-I636 HydrophobicContact CE3-CG2 4.5Å; W633-I636 HydrophobicContact CZ3-CG1 4.49Å; W633-I636 HydrophobicContact CZ3-CG2 4.47Å; W633-I636 PolarHBondContact O-N 2.74Å; I636-S638 VanDerWaalsContact C-N 3.35Å; I636-F639 HydrophobicContact CD1-CD2 4.18Å; I636-F639 HydrophobicContact CD1-CE2 4.33Å; I636-F639 PolarHBondContact O-N 3.26Å; I636-R644 HydrophobicContact CG2-CG 4.11Å; I636-R644 PolarHBondContact O-NE 2.78Å; I636-R644 VanDerWaalsContact O-NE 3.09Å; I636-V647 HydrophobicContact CD1-CB 4.27Å; I636-V647 HydrophobicContact CD1-CG1 3.81Å; I636-V647 HydrophobicContact CD1-CG2 3.98Å
637L88.7Confident87.5Confident5 Ų528.4 Ų28.43%0.02614%0.138CC..Hα-helixtrans-64.6-38.1173.2-82.3-177.6000112.9I320 F354 I359 V609 W633 K634 C635 F639 R644I320-L637 HydrophobicContact CD1-CB 4.42Å; F354-L637 HydrophobicContact CD1-CD1 3.72Å; F354-L637 HydrophobicContact CD1-CD2 3.83Å; F354-L637 HydrophobicContact CD1-CG 4Å; F354-L637 HydrophobicContact CD2-CD1 3.68Å; F354-L637 HydrophobicContact CE1-CD1 3.36Å; F354-L637 HydrophobicContact CE1-CD2 3.69Å; F354-L637 HydrophobicContact CE1-CG 3.44Å; F354-L637 VanDerWaalsContact CE1-CG 3.44Å; F354-L637 HydrophobicContact CE2-CD1 3.31Å; F354-L637 HydrophobicContact CE2-CG 4.26Å; F354-L637 HydrophobicContact CG-CD1 3.84Å; F354-L637 HydrophobicContact CZ-CD1 3.1Å; F354-L637 HydrophobicContact CZ-CD2 4.3Å; F354-L637 HydrophobicContact CZ-CG 3.55Å; I359-L637 HydrophobicContact CG2-CD2 4.38Å; V609-L637 HydrophobicContact CB-CD2 4.02Å; V609-L637 HydrophobicContact CG1-CD2 3.86Å; V609-L637 HydrophobicContact CG1-CG 4.18Å; V609-L637 HydrophobicContact CG2-CD2 4.33Å; W633-L637 PolarHBondContact O-N 3.04Å; K634-L637 PolarHBondContact O-N 3.22Å; C635-L637 VanDerWaalsContact C-N 3.32Å; C635-L637 PolarHBondContact O-N 3.1Å; L637-F639 PolarHBondContact O-N 2.91Å; L637-R644 PolarHBondContact O-NH2 3.06Å; L637-R644 VanDerWaalsContact O-NH2 3.11Å
638S86.3Confident87.5Confident29 Ų2925.8 Ų25.820%0.20313%0.126CC..Hα-helixtrans-69.3-18.6178.874.80000113.7K634 C635 I636K634-S638 PolarHBondContact O-N 3.06Å; C635-S638 PolarHBondContact O-N 2.9Å; C635-S638 VanDerWaalsContact O-N 3.08Å; C635-S638 PolarHBondContact O-OG 2.8Å; I636-S638 VanDerWaalsContact C-N 3.35Å
639F86.4Confident86.9Confident15 Ų1527 Ų277%0.06613%0.131CC..SBendtrans-81145.5177.7-69.2-20000111.4C635 I636 L637 M643 R644 V647 K707 L710 L711C635-F639 WeakPolarHBondContact O-CG 3.21Å; C635-F639 PolarHBondContact O-N 2.99Å; C635-F639 WeakPolarHBondContact SG-CZ 3.01Å; I636-F639 HydrophobicContact CD1-CD2 4.18Å; I636-F639 HydrophobicContact CD1-CE2 4.33Å; I636-F639 PolarHBondContact O-N 3.26Å; L637-F639 PolarHBondContact O-N 2.91Å; F639-M643 HydrophobicContact CB-CB 3.91Å; F639-M643 HydrophobicContact CB-CG 3.93Å; F639-M643 HydrophobicContact CD1-CB 4.39Å; F639-M643 HydrophobicContact CD1-CG 3.67Å; F639-M643 HydrophobicContact CD2-CB 4.35Å; F639-M643 HydrophobicContact CD2-CG 3.51Å; F639-M643 HydrophobicContact CE1-CG 3.94Å; F639-M643 HydrophobicContact CE2-CG 3.8Å; F639-M643 HydrophobicContact CG-CB 4Å; F639-M643 HydrophobicContact CG-CG 3.43Å; F639-M643 VanDerWaalsContact CG-CG 3.43Å; F639-M643 HydrophobicContact CZ-CG 3.99Å; F639-R644 HydrophobicContact CB-CG 4Å; F639-R644 PolarHBondContact O-NE 3.36Å; F639-R644 PolarHBondContact O-NH2 2.97Å; F639-V647 HydrophobicContact CD2-CG2 3.94Å; F639-V647 HydrophobicContact CE2-CG2 3.74Å; F639-K707 HydrophobicContact CE1-CG 4.3Å; F639-K707 HydrophobicContact CZ-CG 4.44Å; F639-L710 HydrophobicContact CE2-CD2 4.25Å; F639-L711 HydrophobicContact CE1-CD2 4.05Å; F639-L711 HydrophobicContact CE1-CG 4.45Å; F639-L711 HydrophobicContact CZ-CD2 3.74Å; F639-L711 HydrophobicContact CZ-CG 4.09Å
640D79.8Confident86.4Confident97 Ų9728.3 Ų28.352%0.51914%0.137SC..  trans-69.5177.2164.661.920.6000111.1E642 M643 R644D640-E642 VanDerWaalsContact C-N 3.3Å; D640-E642 PolarHBondContact O-N 3.5Å; D640-E642 PolarHBondContact OD1-N 3.27Å; D640-M643 VanDerWaalsContact OD1-CB 3.28Å; D640-M643 WeakPolarHBondContact OD1-CB 3.41Å; D640-M643 PolarHBondContact OD1-N 3.07Å; D640-R644 WeakPolarHBondContact O-CB 3.44Å; D640-R644 WeakPolarHBondContact O-CD 3.34Å; D640-R644 WeakPolarHBondContact O-CG 3.34Å; D640-R644 PolarHBondContact O-N 2.67Å
641N79.3Confident86.2Confident50 Ų5026.8 Ų26.827%0.26713%0.13SC..Hα-helixtrans-66.7-31.2-177.1-166.571000113.3Q605 K606 I607 A645Q605-N641 PolarHBondContact O-ND2 2.88Å; K606-N641 WeakPolarHBondContact CA-OD1 3.46Å; I607-N641 PolarHBondContact N-OD1 3.13Å; N641-A645 WeakPolarHBondContact O-CB 3.22Å; N641-A645 PolarHBondContact O-N 3.25Å
642E77.2Confident85.7Confident110 Ų11026.3 Ų26.351%0.51413%0.128SC..Hα-helixtrans-66.5-50.5178.4-175.2-174.6156.800110.7D640 R644 A645 R646D640-E642 VanDerWaalsContact C-N 3.3Å; D640-E642 PolarHBondContact O-N 3.5Å; D640-E642 PolarHBondContact OD1-N 3.27Å; E642-R644 VanDerWaalsContact C-N 3.33Å; E642-R644 PolarHBondContact O-N 2.92Å; E642-A645 WeakPolarHBondContact O-CA 3.3Å; E642-A645 WeakPolarHBondContact O-CB 3.46Å; E642-A645 PolarHBondContact O-N 2.95Å; E642-R646 PolarHBondContact O-N 3.44Å; E642-R646 IonicContact OE1-CZ 2.7Å; E642-R646 VanDerWaalsContact OE1-CZ 3.3Å; E642-R646 IonicContact OE1-NH1 2.76Å; E642-R646 PolarHBondContact OE1-NH1 2.85Å; E642-R646 IonicContact OE1-NH2 3.17Å; E642-R646 PolarHBondContact OE1-NH2 3.43Å
643M81.6Confident84.5Confident32 Ų3226.7 Ų26.716%0.15813%0.131CC..Hα-helixtrans-66.9-35.4179.1-1766068.200111.6F639 D640 A645 R646 V647 L711F639-M643 HydrophobicContact CB-CB 3.91Å; F639-M643 HydrophobicContact CB-CG 3.93Å; F639-M643 HydrophobicContact CD1-CB 4.39Å; F639-M643 HydrophobicContact CD1-CG 3.67Å; F639-M643 HydrophobicContact CD2-CB 4.35Å; F639-M643 HydrophobicContact CD2-CG 3.51Å; F639-M643 HydrophobicContact CE1-CG 3.94Å; F639-M643 HydrophobicContact CE2-CG 3.8Å; F639-M643 HydrophobicContact CG-CB 4Å; F639-M643 HydrophobicContact CG-CG 3.43Å; F639-M643 VanDerWaalsContact CG-CG 3.43Å; F639-M643 HydrophobicContact CZ-CG 3.99Å; D640-M643 VanDerWaalsContact OD1-CB 3.28Å; D640-M643 WeakPolarHBondContact OD1-CB 3.41Å; D640-M643 PolarHBondContact OD1-N 3.07Å; M643-A645 VanDerWaalsContact C-N 3.27Å; M643-A645 PolarHBondContact O-N 2.96Å; M643-R646 PolarHBondContact O-N 2.87Å; M643-R646 HydrophobicContact SD-CB 4.34Å; M643-V647 WeakPolarHBondContact O-CG2 3.48Å; M643-V647 PolarHBondContact O-N 3.27Å; M643-L711 HydrophobicContact CE-CD2 3.69Å; M643-L711 HydrophobicContact CG-CD2 4.28Å; M643-L711 HydrophobicContact SD-CD2 3.55Å; M643-L711 VanDerWaalsContact SD-CD2 3.55Å
644R88.2Confident83.4Confident20 Ų2027.5 Ų27.58%0.07514%0.136CC..Hα-helixtrans-57.9-41.1169.7-71.3168.4-167.2176.16.1111.5I359 I607 V609 W612 I636 L637 F639 D640 E642 V647 L648I359-R644 PolarHBondContact O-NH1 2.81Å; I359-R644 PolarHBondContact O-NH2 2.97Å; I607-R644 HydrophobicContact CB-CB 4.34Å; I607-R644 HydrophobicContact CD1-CB 3.84Å; I607-R644 HydrophobicContact CG2-CB 4.44Å; V609-R644 VanDerWaalsContact CG2-CZ 3.46Å; W612-R644 HydrophobicContact CZ3-CB 4.41Å; I636-R644 HydrophobicContact CG2-CG 4.11Å; I636-R644 PolarHBondContact O-NE 2.78Å; I636-R644 VanDerWaalsContact O-NE 3.09Å; L637-R644 PolarHBondContact O-NH2 3.06Å; L637-R644 VanDerWaalsContact O-NH2 3.11Å; F639-R644 HydrophobicContact CB-CG 4Å; F639-R644 PolarHBondContact O-NE 3.36Å; F639-R644 PolarHBondContact O-NH2 2.97Å; D640-R644 WeakPolarHBondContact O-CB 3.44Å; D640-R644 WeakPolarHBondContact O-CD 3.34Å; D640-R644 WeakPolarHBondContact O-CG 3.34Å; D640-R644 PolarHBondContact O-N 2.67Å; E642-R644 VanDerWaalsContact C-N 3.33Å; E642-R644 PolarHBondContact O-N 2.92Å; R644-V647 PolarHBondContact O-N 2.98Å; R644-L648 PolarHBondContact O-N 3.22Å
645A81.2Confident82.6Confident11 Ų1126.6 Ų26.69%0.09113%0.133CC..Hα-helixtrans-66.8-39.8177.900000111.7I607 N641 E642 M643 L648 Q649I607-A645 HydrophobicContact CD1-CB 4.02Å; N641-A645 WeakPolarHBondContact O-CB 3.22Å; N641-A645 PolarHBondContact O-N 3.25Å; E642-A645 WeakPolarHBondContact O-CA 3.3Å; E642-A645 WeakPolarHBondContact O-CB 3.46Å; E642-A645 PolarHBondContact O-N 2.95Å; M643-A645 VanDerWaalsContact C-N 3.27Å; M643-A645 PolarHBondContact O-N 2.96Å; A645-L648 WeakPolarHBondContact O-CB 3.3Å; A645-L648 PolarHBondContact O-N 2.87Å; A645-Q649 WeakPolarHBondContact O-CB 3.39Å; A645-Q649 PolarHBondContact O-N 2.91Å
646R81.9Confident81.8Confident93 Ų9328.2 Ų28.235%0.35114%0.139SC..Hα-helixtrans-62.7-41.4172.8-70.7-161.5177.8116.915.8112.9E642 M643 L648 Q649 F650 I714E642-R646 PolarHBondContact O-N 3.44Å; E642-R646 IonicContact OE1-CZ 2.7Å; E642-R646 VanDerWaalsContact OE1-CZ 3.3Å; E642-R646 IonicContact OE1-NH1 2.76Å; E642-R646 PolarHBondContact OE1-NH1 2.85Å; E642-R646 IonicContact OE1-NH2 3.17Å; E642-R646 PolarHBondContact OE1-NH2 3.43Å; M643-R646 PolarHBondContact O-N 2.87Å; M643-R646 HydrophobicContact SD-CB 4.34Å; R646-L648 VanDerWaalsContact C-N 3.32Å; R646-L648 PolarHBondContact O-N 3.44Å; R646-Q649 PolarHBondContact O-N 3.49Å; R646-F650 WeakPolarHBondContact O-CB 3.46Å; R646-F650 PolarHBondContact O-N 3.33Å; R646-I714 HydrophobicContact CB-CG2 3.91Å
647V89.1Confident81.3Confident0 Ų028.3 Ų28.30%014%0.14CC..Hα-helixtrans-61.4-43.6173.6178.20000110.6W612 I636 F639 M643 R644 Q649 F650 V651 L710 I714W612-V647 HydrophobicContact CH2-CB 4.04Å; W612-V647 HydrophobicContact CH2-CG1 3.77Å; W612-V647 HydrophobicContact CZ2-CG1 4.23Å; I636-V647 HydrophobicContact CD1-CB 4.27Å; I636-V647 HydrophobicContact CD1-CG1 3.81Å; I636-V647 HydrophobicContact CD1-CG2 3.98Å; F639-V647 HydrophobicContact CD2-CG2 3.94Å; F639-V647 HydrophobicContact CE2-CG2 3.74Å; M643-V647 WeakPolarHBondContact O-CG2 3.48Å; M643-V647 PolarHBondContact O-N 3.27Å; R644-V647 PolarHBondContact O-N 2.98Å; V647-Q649 VanDerWaalsContact C-N 3.35Å; V647-F650 PolarHBondContact O-N 2.6Å; V647-V651 WeakPolarHBondContact O-CG2 3.4Å; V647-V651 PolarHBondContact O-N 2.94Å; V647-V651 VanDerWaalsContact O-N 3.12Å; V647-L710 HydrophobicContact CG2-CD2 4.49Å; V647-I714 HydrophobicContact CB-CD1 4.23Å; V647-I714 HydrophobicContact CG2-CD1 3.51Å
648L87.8Confident80.6Confident0 Ų029 Ų290%015%0.145CC..Hα-helixtrans-63.2-42.8178.3-173.657.2000111.3I607 W612 R644 A645 R646 V651 S652 T654 V657 F662 F674I607-L648 HydrophobicContact CD1-CB 4.46Å; I607-L648 HydrophobicContact CD1-CD2 4.13Å; W612-L648 HydrophobicContact CH2-CB 4.18Å; W612-L648 HydrophobicContact CZ2-CD1 4.17Å; R644-L648 PolarHBondContact O-N 3.22Å; A645-L648 WeakPolarHBondContact O-CB 3.3Å; A645-L648 PolarHBondContact O-N 2.87Å; R646-L648 VanDerWaalsContact C-N 3.32Å; R646-L648 PolarHBondContact O-N 3.44Å; L648-V651 PolarHBondContact O-N 3.39Å; L648-S652 WeakPolarHBondContact O-CA 3.32Å; L648-S652 VanDerWaalsContact O-CB 3.31Å; L648-S652 WeakPolarHBondContact O-CB 3.49Å; L648-S652 PolarHBondContact O-N 3.44Å; L648-S652 PolarHBondContact O-OG 2.97Å; L648-T654 CarbonylContact C-O 3.55Å; L648-T654 WeakPolarHBondContact CG-O 3.45Å; L648-V657 HydrophobicContact CD2-CG2 3.56Å; L648-F662 HydrophobicContact CD1-CE1 3.66Å; L648-F662 HydrophobicContact CD1-CZ 4.26Å; L648-F662 HydrophobicContact CD2-CE1 4.31Å; L648-F662 HydrophobicContact CD2-CZ 4.17Å; L648-F674 HydrophobicContact CD1-CD2 4.47Å
649Q81Confident79.7Confident38 Ų3828.5 Ų28.518%0.17814%0.139CC..Hα-helixtrans-63-45.4176.8-175.2-170.8-14.100111.5F441 A645 R646 V647 V651 G653 T654F441-Q649 HydrophobicContact CE2-CG 4.38Å; F441-Q649 HydrophobicContact CZ-CG 4.27Å; A645-Q649 WeakPolarHBondContact O-CB 3.39Å; A645-Q649 PolarHBondContact O-N 2.91Å; R646-Q649 PolarHBondContact O-N 3.49Å; V647-Q649 VanDerWaalsContact C-N 3.35Å; Q649-V651 VanDerWaalsContact C-N 3.3Å; Q649-V651 PolarHBondContact O-N 2.81Å; Q649-G653 WeakPolarHBondContact O-CA 3.47Å; Q649-G653 PolarHBondContact O-N 3.5Å; Q649-T654 WeakPolarHBondContact CA-O 3.44Å; Q649-T654 PolarHBondContact N-O 3.03Å
650F83.9Confident79.1Confident27 Ų2729.9 Ų29.912%0.11815%0.147CC..Hα-helixtrans-54.9-46.7175.4175.9-111.9000111.5R646 V647 A688 L695 A713 I714R646-F650 WeakPolarHBondContact O-CB 3.46Å; R646-F650 PolarHBondContact O-N 3.33Å; V647-F650 PolarHBondContact O-N 2.6Å; F650-A688 HydrophobicContact CD1-CB 4.07Å; F650-A688 HydrophobicContact CD2-CB 4.41Å; F650-A688 HydrophobicContact CE1-CB 3.89Å; F650-A688 HydrophobicContact CE2-CB 4.24Å; F650-A688 HydrophobicContact CG-CB 4.33Å; F650-A688 HydrophobicContact CZ-CB 3.98Å; F650-A688 WeakPolarHBondContact O-CB 3.49Å; F650-L695 HydrophobicContact CD1-CD1 4.37Å; F650-L695 HydrophobicContact CE1-CD1 3.86Å; F650-A713 HydrophobicContact CE2-CB 4.42Å; F650-A713 HydrophobicContact CZ-CB 3.96Å; F650-I714 HydrophobicContact CB-CG1 3.99Å; F650-I714 HydrophobicContact CD1-CG1 4.16Å; F650-I714 HydrophobicContact CD2-CG1 4.46Å; F650-I714 HydrophobicContact CG-CG1 3.96Å
651V86Confident79.1Confident0 Ų025.5 Ų25.50%013%0.125CC..Hα-helixtrans-84.8-29.9-173.5-178.80000114.1V647 L648 Q649 F674 T690 L695V647-V651 WeakPolarHBondContact O-CG2 3.4Å; V647-V651 PolarHBondContact O-N 2.94Å; V647-V651 VanDerWaalsContact O-N 3.12Å; L648-V651 PolarHBondContact O-N 3.39Å; Q649-V651 VanDerWaalsContact C-N 3.3Å; Q649-V651 PolarHBondContact O-N 2.81Å; V651-F674 HydrophobicContact CB-CD2 4.49Å; V651-F674 HydrophobicContact CB-CE2 3.55Å; V651-F674 HydrophobicContact CB-CZ 4.03Å; V651-F674 HydrophobicContact CG1-CD2 3.92Å; V651-F674 HydrophobicContact CG1-CE2 3.26Å; V651-F674 HydrophobicContact CG1-CZ 3.67Å; V651-F674 HydrophobicContact CG2-CE2 4Å; V651-F674 HydrophobicContact CG2-CZ 3.98Å; V651-T690 WeakPolarHBondContact O-CA 3.41Å; V651-L695 HydrophobicContact CG1-CB 3.96Å; V651-L695 HydrophobicContact CG2-CB 3.9Å; V651-L695 HydrophobicContact CG2-CD1 3.92Å; V651-L695 HydrophobicContact CG2-CD2 4.43Å; V651-L695 HydrophobicContact CG2-CG 4.3Å
652S79.8Confident79.5Confident0 Ų023.1 Ų23.10%011%0.113CC..Hα-helixtrans-120.8-7.1-170.675.80000113.8R437 L648 T654 N693R437-S652 PolarHBondContact NE-O 3.01Å; R437-S652 PolarHBondContact NH1-O 2.97Å; L648-S652 WeakPolarHBondContact O-CA 3.32Å; L648-S652 VanDerWaalsContact O-CB 3.31Å; L648-S652 WeakPolarHBondContact O-CB 3.49Å; L648-S652 PolarHBondContact O-N 3.44Å; L648-S652 PolarHBondContact O-OG 2.97Å; S652-T654 PolarHBondContact O-N 3.47Å; S652-T654 WeakPolarHBondContact OG-CG2 3.19Å; S652-T654 PolarHBondContact OG-N 2.96Å; S652-T654 PolarHBondContact OG-O 3.1Å; S652-N693 WeakPolarHBondContact CB-OD1 3.2Å
653G71Confident79.9Confident8 Ų824.4 Ų24.48%0.08211%0.113CC..SBendtrans67.514.9-174.100000113.7Q649Q649-G653 WeakPolarHBondContact O-CA 3.47Å; Q649-G653 PolarHBondContact O-N 3.5Å
654T70.2Confident80Confident18 Ų1824.5 Ų24.511%0.1111%0.113CC..  trans-138.4139170.5179.70000109.4L648 Q649 S652 R656L648-T654 CarbonylContact C-O 3.55Å; L648-T654 WeakPolarHBondContact CG-O 3.45Å; Q649-T654 WeakPolarHBondContact CA-O 3.44Å; Q649-T654 PolarHBondContact N-O 3.03Å; S652-T654 PolarHBondContact O-N 3.47Å; S652-T654 WeakPolarHBondContact OG-CG2 3.19Å; S652-T654 PolarHBondContact OG-N 2.96Å; S652-T654 PolarHBondContact OG-O 3.1Å; T654-R656 PolarHBondContact O-N 2.61Å; T654-R656 PolarHBondContact OG1-N 3.02Å
655S71.7Confident79.6Confident6 Ų623.7 Ų23.74%0.04211%0.11CC..SBendtrans-79.5-2.8172.755.60000112.7F441 D500F441-S655 WeakPolarHBondContact CE2-OG 3.18Å; D500-S655 PolarHBondContact OD2-OG 3.39Å
656R74.9Confident79.2Confident34 Ų3425.8 Ų25.813%0.12812%0.116CC..  trans-121.4147.9-165.2-56.5-61.3175.3-168.6-3.7113.2L498 D500 T654L498-R656 HydrophobicContact CB-CB 4.37Å; L498-R656 HydrophobicContact CD1-CB 3.65Å; D500-R656 IonicContact OD1-CZ 3.64Å; D500-R656 IonicContact OD1-NE 2.76Å; D500-R656 PolarHBondContact OD1-NE 3.1Å; D500-R656 IonicContact OD1-NH2 3.29Å; D500-R656 PolarHBondContact OD1-NH2 2.77Å; D500-R656 IonicContact OD2-NH2 3.44Å; T654-R656 PolarHBondContact O-N 2.61Å; T654-R656 PolarHBondContact OG1-N 3.02Å
657V81.6Confident78.7Confident1 Ų121.5 Ų21.51%0.00610%0.101CC..BIsolated β-bridgetrans-100.5134.5178.6-172.20000109L604 I607 L648 F662L604-V657 HydrophobicContact CB-CB 4.16Å; L604-V657 HydrophobicContact CD1-CB 4.11Å; L604-V657 HydrophobicContact CD1-CG1 4.05Å; L604-V657 HydrophobicContact CG-CB 4.37Å; L604-V657 PolarHBondContact N-O 3.43Å; I607-V657 HydrophobicContact CG1-CG2 3.93Å; I607-V657 HydrophobicContact CG2-CG2 4.44Å; L648-V657 HydrophobicContact CD2-CG2 3.56Å; V657-F662 HydrophobicContact CB-CE2 4.21Å; V657-F662 HydrophobicContact CB-CZ 4.5Å; V657-F662 HydrophobicContact CG1-CD2 3.6Å; V657-F662 HydrophobicContact CG1-CE2 3.66Å; V657-F662 HydrophobicContact CG1-CG 4.15Å; V657-F662 HydrophobicContact CG1-CZ 4.23Å; V657-F662 HydrophobicContact CG2-CD2 4.22Å; V657-F662 HydrophobicContact CG2-CE1 4.25Å; V657-F662 HydrophobicContact CG2-CE2 3.4Å; V657-F662 VanDerWaalsContact CG2-CE2 3.4Å; V657-F662 HydrophobicContact CG2-CZ 3.41Å; V657-F662 VanDerWaalsContact CG2-CZ 3.41Å
658P73.4Confident77.5Confident20 Ų2022.5 Ų22.513%0.1311%0.108CC..  trans-54.6151.2171-2534.5000111.4N660 G661 E664 L665P658-N660 PolarHBondContact O-N 2.81Å; P658-G661 WeakPolarHBondContact O-CA 3.45Å; P658-G661 PolarHBondContact O-N 3.31Å; P658-E664 WeakPolarHBondContact CG-O 3.44Å; P658-L665 HydrophobicContact CG-CD2 4.16Å
659M67.2Low76.4Confident18 Ų1828.9 Ų28.99%0.08914%0.141CC..THydrogen-bonded Turntrans-58.3-34.9-176.6-171.5-120.4-11700113.8Y366 Y370 L599 L604 G661Y366-M659 HydrophobicContact CD1-CE 3.69Å; Y366-M659 HydrophobicContact CD1-CG 4.4Å; Y366-M659 HydrophobicContact CD1-SD 4.29Å; Y366-M659 HydrophobicContact CD2-CE 4.15Å; Y366-M659 HydrophobicContact CD2-CG 3.75Å; Y366-M659 HydrophobicContact CD2-SD 3.64Å; Y366-M659 HydrophobicContact CE1-CE 4.18Å; Y366-M659 HydrophobicContact CE1-CG 4.2Å; Y366-M659 HydrophobicContact CE2-CG 3.44Å; Y366-M659 VanDerWaalsContact CE2-CG 3.44Å; Y366-M659 HydrophobicContact CE2-SD 4.01Å; Y366-M659 HydrophobicContact CG-CE 3.69Å; Y366-M659 HydrophobicContact CG-CG 4.21Å; Y366-M659 HydrophobicContact CG-SD 3.78Å; Y370-M659 HydrophobicContact CD1-CE 3.08Å; Y370-M659 HydrophobicContact CD1-SD 3.22Å; Y370-M659 WeakPolarHBondContact CD1-SD 3.34Å; Y370-M659 HydrophobicContact CD2-CE 3.63Å; Y370-M659 HydrophobicContact CE1-CB 4.29Å; Y370-M659 HydrophobicContact CE1-CE 3.22Å; Y370-M659 HydrophobicContact CE1-CG 4.3Å; Y370-M659 HydrophobicContact CE1-SD 3.31Å; Y370-M659 WeakPolarHBondContact CE1-SD 3.37Å; Y370-M659 HydrophobicContact CE2-CE 3.77Å; Y370-M659 HydrophobicContact CG-CE 3.26Å; Y370-M659 HydrophobicContact CG-SD 4Å; L599-M659 HydrophobicContact CB-CB 4.49Å; L599-M659 HydrophobicContact CB-CE 4.13Å; L599-M659 HydrophobicContact CB-CG 4.22Å; L599-M659 HydrophobicContact CD1-CE 3.58Å; L599-M659 HydrophobicContact CD1-CG 4.3Å; L599-M659 HydrophobicContact CD2-CG 4.19Å; L599-M659 HydrophobicContact CG-CE 4.44Å; L599-M659 HydrophobicContact CG-CG 4.49Å; L604-M659 HydrophobicContact CD2-CG 4.45Å; M659-G661 PolarHBondContact O-N 3.11Å; M659-G661 VanDerWaalsContact O-N 3.14Å
660N73.2Confident76Confident44 Ų4428.2 Ų28.224%0.23515%0.145CC..THydrogen-bonded Turntrans-77.112.4174.1-72.1-41.5000113.6P658 E664P658-N660 PolarHBondContact O-N 2.81Å; N660-E664 HydrophobicContact CB-CB 4.17Å; N660-E664 VanDerWaalsContact CB-CD 3.48Å; N660-E664 HydrophobicContact CB-CG 3.95Å; N660-E664 WeakPolarHBondContact CB-OE2 3.28Å; N660-E664 PolarHBondContact ND2-OE1 3.3Å; N660-E664 PolarHBondContact ND2-OE2 2.92Å
661G81.3Confident75.8Confident5 Ų532.1 Ų32.15%0.05217%0.167CC..  trans78.5-167.618000000114D611 P658 M659 R663 E664D611-G661 WeakPolarHBondContact OD2-CA 3.38Å; P658-G661 WeakPolarHBondContact O-CA 3.45Å; P658-G661 PolarHBondContact O-N 3.31Å; M659-G661 PolarHBondContact O-N 3.11Å; M659-G661 VanDerWaalsContact O-N 3.14Å; G661-R663 PolarHBondContact O-N 2.9Å; G661-R663 VanDerWaalsContact O-N 3.14Å; G661-E664 PolarHBondContact O-N 2.8Å
662F87.9Confident75.6Confident1 Ų134.8 Ų34.80%0.00418%0.179CC..G310 helixtrans-63.9-18.2-179-77.9-95.2000113.6I607 D611 W612 N615 L648 V657 E664 L665I607-F662 HydrophobicContact CG2-CE2 3.91Å; I607-F662 HydrophobicContact CG2-CZ 3.85Å; D611-F662 WeakPolarHBondContact OD2-CD2 3.31Å; D611-F662 PolarHBondContact OD2-N 2.86Å; W612-F662 VanDerWaalsContact CA-CG 3.47Å; W612-F662 HydrophobicContact CB-CD1 4.03Å; W612-F662 HydrophobicContact CB-CD2 3.6Å; W612-F662 HydrophobicContact CB-CE1 3.9Å; W612-F662 HydrophobicContact CB-CE2 3.42Å; W612-F662 VanDerWaalsContact CB-CE2 3.42Å; W612-F662 HydrophobicContact CB-CG 3.92Å; W612-F662 HydrophobicContact CB-CZ 3.58Å; W612-F662 AromaticContact CD1-CD1 3.23Å; W612-F662 AromaticContact CD1-CE1 3.17Å; W612-F662 AromaticContact CD1-CG 3.92Å; W612-F662 AromaticContact CD1-CZ 3.76Å; W612-F662 HydrophobicContact CD2-CD1 4.27Å; W612-F662 AromaticContact CD2-CE1 3.44Å; W612-F662 HydrophobicContact CD2-CE1 3.44Å; W612-F662 VanDerWaalsContact CD2-CE1 3.44Å; W612-F662 HydrophobicContact CD2-CE2 4.15Å; W612-F662 AromaticContact CD2-CZ 3.36Å; W612-F662 HydrophobicContact CD2-CZ 3.36Å; W612-F662 AromaticContact CE2-CE1 3.54Å; W612-F662 AromaticContact CE2-CZ 3.92Å; W612-F662 HydrophobicContact CE3-CE1 4.22Å; W612-F662 HydrophobicContact CE3-CE2 4.47Å; W612-F662 AromaticContact CE3-CZ 3.73Å; W612-F662 HydrophobicContact CE3-CZ 3.73Å; W612-F662 AromaticContact CG-CD1 3.6Å; W612-F662 HydrophobicContact CG-CD1 3.6Å; W612-F662 HydrophobicContact CG-CD2 4.07Å; W612-F662 AromaticContact CG-CE1 3.24Å; W612-F662 HydrophobicContact CG-CE1 3.24Å; W612-F662 AromaticContact CG-CE2 3.72Å; W612-F662 HydrophobicContact CG-CE2 3.72Å; W612-F662 HydrophobicContact CG-CG 4.02Å; W612-F662 AromaticContact CG-CZ 3.3Å; W612-F662 HydrophobicContact CG-CZ 3.3Å; W612-F662 HydrophobicContact CZ2-CE1 4.36Å; W612-F662 HydrophobicContact CZ3-CZ 4.5Å; W612-F662 AromaticContact NE1-CD1 3.78Å; W612-F662 AromaticContact NE1-CE1 3.39Å; N615-F662 HydrophobicContact CB-CB 3.65Å; L648-F662 HydrophobicContact CD1-CE1 3.66Å; L648-F662 HydrophobicContact CD1-CZ 4.26Å; L648-F662 HydrophobicContact CD2-CE1 4.31Å; L648-F662 HydrophobicContact CD2-CZ 4.17Å; V657-F662 HydrophobicContact CB-CE2 4.21Å; V657-F662 HydrophobicContact CB-CZ 4.5Å; V657-F662 HydrophobicContact CG1-CD2 3.6Å; V657-F662 HydrophobicContact CG1-CE2 3.66Å; V657-F662 HydrophobicContact CG1-CG 4.15Å; V657-F662 HydrophobicContact CG1-CZ 4.23Å; V657-F662 HydrophobicContact CG2-CD2 4.22Å; V657-F662 HydrophobicContact CG2-CE1 4.25Å; V657-F662 HydrophobicContact CG2-CE2 3.4Å; V657-F662 VanDerWaalsContact CG2-CE2 3.4Å; V657-F662 HydrophobicContact CG2-CZ 3.41Å; V657-F662 VanDerWaalsContact CG2-CZ 3.41Å; F662-E664 PolarHBondContact O-N 3.47Å; F662-L665 HydrophobicContact CB-CD1 4.43Å; F662-L665 HydrophobicContact CD1-CD1 3.51Å; F662-L665 HydrophobicContact CD1-CG 4.16Å; F662-L665 HydrophobicContact CE1-CD1 4.2Å; F662-L665 HydrophobicContact CG-CD1 4.37Å; F662-L665 PolarHBondContact O-N 2.87Å
663R85.6Confident76.2Confident137 Ų13738.4 Ų38.452%0.51720%0.195SC..G310 helixtrans-59-33.4174.7-173.3169.360.2-166.2-7.7112.5N615 G661N615-R663 WeakPolarHBondContact OD1-CA 3.46Å; N615-R663 VanDerWaalsContact OD1-CB 3.26Å; N615-R663 WeakPolarHBondContact OD1-CB 3.39Å; G661-R663 PolarHBondContact O-N 2.9Å; G661-R663 VanDerWaalsContact O-N 3.14Å
664E82.3Confident77.3Confident33 Ų3338 Ų3815%0.15419%0.191CC..G310 helixtrans-109.927.5-176.8-66.7-172.1-169.600112.9K371 P658 N660 G661 F662 Y666 L671K371-E664 IonicContact NZ-OE1 2.71Å; P658-E664 WeakPolarHBondContact CG-O 3.44Å; N660-E664 HydrophobicContact CB-CB 4.17Å; N660-E664 VanDerWaalsContact CB-CD 3.48Å; N660-E664 HydrophobicContact CB-CG 3.95Å; N660-E664 WeakPolarHBondContact CB-OE2 3.28Å; N660-E664 PolarHBondContact ND2-OE1 3.3Å; N660-E664 PolarHBondContact ND2-OE2 2.92Å; G661-E664 PolarHBondContact O-N 2.8Å; F662-E664 PolarHBondContact O-N 3.47Å; E664-Y666 WeakPolarHBondContact O-CD2 3.21Å; E664-Y666 WeakPolarHBondContact O-CE2 3.49Å; E664-Y666 PolarHBondContact O-N 3.42Å; E664-L671 HydrophobicContact CB-CD2 4.06Å; E664-L671 HydrophobicContact CG-CD2 4.33Å
665L80.9Confident78.4Confident3 Ų337.2 Ų37.22%0.01619%0.186CC..  trans-55.9136.8166.9-79.4176000110.6P658 F662 L671 Q672 F674P658-L665 HydrophobicContact CG-CD2 4.16Å; F662-L665 HydrophobicContact CB-CD1 4.43Å; F662-L665 HydrophobicContact CD1-CD1 3.51Å; F662-L665 HydrophobicContact CD1-CG 4.16Å; F662-L665 HydrophobicContact CE1-CD1 4.2Å; F662-L665 HydrophobicContact CG-CD1 4.37Å; F662-L665 PolarHBondContact O-N 2.87Å; L665-L671 CarbonylContact O-C 3.51Å; L665-L671 WeakPolarHBondContact O-CA 3.06Å; L665-Q672 CarbonylContact C-O 3.46Å; L665-Q672 VanDerWaalsContact CB-O 3.23Å; L665-Q672 WeakPolarHBondContact CB-O 3.23Å; L665-Q672 CarbonylContact O-C 3.59Å; L665-Q672 PolarHBondContact O-N 2.87Å; L665-Q672 VanDerWaalsContact O-O 3.13Å; L665-F674 HydrophobicContact CD1-CB 3.84Å
666Y72.9Confident79.7Confident56 Ų5636.9 Ų36.922%0.2218%0.184CC..EExtended strand (participates in β ladder)trans-99.9134.4176.4-78.6-96.2000110R378 R437 E664 G670 L671 N693R378-Y666 VanDerWaalsContact CZ-OH 3.3Å; R378-Y666 PolarHBondContact NH1-OH 3.05Å; R378-Y666 PolarHBondContact NH2-OH 3.09Å; R437-Y666 PolarHBondContact NH1-O 2.83Å; E664-Y666 WeakPolarHBondContact O-CD2 3.21Å; E664-Y666 WeakPolarHBondContact O-CE2 3.49Å; E664-Y666 PolarHBondContact O-N 3.42Å; Y666-G670 CarbonylContact C-O 3.52Å; Y666-G670 WeakPolarHBondContact CA-O 3.13Å; Y666-L671 HydrophobicContact CD1-CD2 4.5Å; Y666-L671 HydrophobicContact CD2-CD2 4.28Å; Y666-L671 HydrophobicContact CE1-CD2 4.04Å; Y666-L671 HydrophobicContact CE2-CD2 3.79Å; Y666-N693 PolarHBondContact O-ND2 2.89Å
667G70.1Confident80.7Confident3 Ų337.5 Ų37.53%0.03119%0.188CC..EExtended strand (participates in β ladder)trans-108.4-157.9166.100000110.4N669 G670 C691G667-N669 PolarHBondContact O-N 2.78Å; G667-G670 PolarHBondContact N-O 2.85Å; G667-C691 WeakPolarHBondContact CA-O 3.29Å
668S63.9Low81.4Confident21 Ų2144 Ų4415%0.14721%0.212CC..THydrogen-bonded Turntrans-56-45.1179.144.20000115Y432 C691Y432-S668 VanDerWaalsContact C-CB 3.49Å; Y432-S668 CarbonylContact O-C 3.58Å; Y432-S668 WeakPolarHBondContact O-CA 3.35Å; Y432-S668 WeakPolarHBondContact O-CB 3.4Å; S668-C691 PolarHBondContact N-O 3.06Å; S668-C691 PolarHBondContact OG-O 2.81Å
669N66.2Low82.1Confident133 Ų13346.1 Ų46.171%0.71122%0.218SC*.THydrogen-bonded Turntrans-112.328.7-170.7-66.5-26.9000113G667G667-N669 PolarHBondContact O-N 2.78Å
670G71.8Confident83.3Confident25 Ų2547.1 Ų47.126%0.25823%0.233SC..EExtended strand (participates in β ladder)trans107-144.2-177.800000112.4Y666 G667 Q672Y666-G670 CarbonylContact C-O 3.52Å; Y666-G670 WeakPolarHBondContact CA-O 3.13Å; G667-G670 PolarHBondContact N-O 2.85Å; G670-Q672 PolarHBondContact O-N 2.84Å
671L80.2Confident84.1Confident108 Ų10847.2 Ų47.257%0.56524%0.237SC*.EExtended strand (participates in β ladder)trans-61.4122.6-176.4-66.5177.6000111.2E664 L665 Y666E664-L671 HydrophobicContact CB-CD2 4.06Å; E664-L671 HydrophobicContact CG-CD2 4.33Å; L665-L671 CarbonylContact O-C 3.51Å; L665-L671 WeakPolarHBondContact O-CA 3.06Å; Y666-L671 HydrophobicContact CD1-CD2 4.5Å; Y666-L671 HydrophobicContact CD2-CD2 4.28Å; Y666-L671 HydrophobicContact CE1-CD2 4.04Å; Y666-L671 HydrophobicContact CE2-CD2 3.79Å
672Q82.6Confident84.5Confident57 Ų5748.3 Ų48.327%0.26625%0.246SC..  trans-144.3110.4-179.6179.455.769.800109.3L665 G670 F692 N693L665-Q672 CarbonylContact C-O 3.46Å; L665-Q672 VanDerWaalsContact CB-O 3.23Å; L665-Q672 WeakPolarHBondContact CB-O 3.23Å; L665-Q672 CarbonylContact O-C 3.59Å; L665-Q672 PolarHBondContact O-N 2.87Å; L665-Q672 VanDerWaalsContact O-O 3.13Å; G670-Q672 PolarHBondContact O-N 2.84Å; Q672-F692 WeakPolarHBondContact CG-O 3.37Å; Q672-N693 HydrophobicContact CG-CB 4.4Å; Q672-N693 PolarHBondContact O-ND2 2.64Å
673K90.6Very high84.6Confident75 Ų7553.5 Ų53.533%0.32627%0.274SS..  trans-65.7151177.1-69.6-170175.4-161.80111.8N615 I617 T675N615-K673 WeakPolarHBondContact O-CD 3.18Å; I617-K673 HydrophobicContact CD1-CB 3.81Å; I617-K673 HydrophobicContact CD1-CD 4.06Å; I617-K673 HydrophobicContact CD1-CG 4.37Å; I617-K673 HydrophobicContact CG1-CB 3.98Å; I617-K673 HydrophobicContact CG1-CD 4.06Å; K673-T675 PolarHBondContact O-N 2.97Å; K673-T675 PolarHBondContact O-OG1 2.75Å; K673-T675 VanDerWaalsContact O-OG1 3.11Å
674F93.9Very high84.9Confident0 Ų050.2 Ų50.20%027%0.265CS..  trans-53.8131.6167.4-167.3-90.1000109.5W612 T616 I617 F632 L648 V651 L665 I676 N693 L695W612-F674 AromaticContact CE2-CE2 3.82Å; W612-F674 AromaticContact CE2-CZ 3.97Å; W612-F674 HydrophobicContact CZ2-CD2 4.15Å; W612-F674 HydrophobicContact CZ2-CE1 4.4Å; W612-F674 AromaticContact CZ2-CE2 3.51Å; W612-F674 HydrophobicContact CZ2-CE2 3.51Å; W612-F674 AromaticContact CZ2-CZ 3.67Å; W612-F674 HydrophobicContact CZ2-CZ 3.67Å; W612-F674 AromaticContact NE1-CD1 3.43Å; W612-F674 AromaticContact NE1-CD2 3.33Å; W612-F674 VanDerWaalsContact NE1-CD2 3.33Å; W612-F674 AromaticContact NE1-CE1 3.63Å; W612-F674 AromaticContact NE1-CE2 3.5Å; W612-F674 AromaticContact NE1-CG 3.28Å; W612-F674 VanDerWaalsContact NE1-CG 3.28Å; W612-F674 AromaticContact NE1-CZ 3.67Å; T616-F674 CarbonylContact C-O 3.56Å; T616-F674 WeakPolarHBondContact CA-O 3.1Å; T616-F674 HydrophobicContact CG2-CD1 3.78Å; T616-F674 HydrophobicContact CG2-CE1 4.46Å; T616-F674 WeakPolarHBondContact OG1-CD1 3.42Å; I617-F674 PolarHBondContact N-O 3.1Å; F632-F674 HydrophobicContact CE1-CE1 4.43Å; F632-F674 HydrophobicContact CZ-CE1 4.26Å; F632-F674 HydrophobicContact CZ-CZ 4.23Å; L648-F674 HydrophobicContact CD1-CD2 4.47Å; V651-F674 HydrophobicContact CB-CD2 4.49Å; V651-F674 HydrophobicContact CB-CE2 3.55Å; V651-F674 HydrophobicContact CB-CZ 4.03Å; V651-F674 HydrophobicContact CG1-CD2 3.92Å; V651-F674 HydrophobicContact CG1-CE2 3.26Å; V651-F674 HydrophobicContact CG1-CZ 3.67Å; V651-F674 HydrophobicContact CG2-CE2 4Å; V651-F674 HydrophobicContact CG2-CZ 3.98Å; L665-F674 HydrophobicContact CD1-CB 3.84Å; F674-I676 HydrophobicContact CD1-CG1 4.15Å; F674-I676 HydrophobicContact CE1-CD1 4.04Å; F674-I676 HydrophobicContact CE1-CG1 3.63Å; F674-N693 CarbonylContact C-O 3.02Å; F674-N693 WeakPolarHBondContact CA-O 3.28Å; F674-L695 HydrophobicContact CZ-CB 4.47Å
675T95.2Very high85.4Confident1 Ų151.9 Ų51.91%0.00627%0.274CS..EExtended strand (participates in β ladder)trans-129.4130.4-174.6-58.10000110.1I617 K619 K673 N693 R694 L695I617-T675 HydrophobicContact CB-CG2 4.41Å; I617-T675 HydrophobicContact CG2-CG2 4.43Å; I617-T675 CarbonylContact O-C 3.54Å; I617-T675 VanDerWaalsContact O-CA 3.23Å; I617-T675 WeakPolarHBondContact O-CA 3.36Å; K619-T675 HydrophobicContact CD-CG2 3.87Å; K619-T675 HydrophobicContact CG-CG2 4.01Å; K673-T675 PolarHBondContact O-N 2.97Å; K673-T675 PolarHBondContact O-OG1 2.75Å; K673-T675 VanDerWaalsContact O-OG1 3.11Å; T675-N693 PolarHBondContact N-O 3.47Å; T675-R694 HydrophobicContact CG2-CG 4.18Å; T675-R694 CarbonylContact O-C 3.43Å; T675-R694 VanDerWaalsContact O-CA 3.25Å; T675-R694 WeakPolarHBondContact O-CA 3.36Å; T675-L695 PolarHBondContact O-N 3.21Å
676I97.6Very high86Confident0 Ų051.9 Ų51.90%028%0.275CS..EExtended strand (participates in β ladder)trans-108.9124.1170-55.8-179.5000108.1T616 I617 Y618 K619 Y622 F632 W633 F674 L695 L697T616-I676 HydrophobicContact CG2-CD1 4.08Å; T616-I676 HydrophobicContact CG2-CG1 3.9Å; I617-I676 PolarHBondContact O-N 2.94Å; Y618-I676 CarbonylContact C-O 3.54Å; Y618-I676 WeakPolarHBondContact CA-O 3.28Å; Y618-I676 HydrophobicContact CD1-CB 4.12Å; Y618-I676 HydrophobicContact CE1-CB 4.49Å; Y618-I676 HydrophobicContact CE1-CD1 4.07Å; K619-I676 PolarHBondContact N-O 3.16Å; Y622-I676 HydrophobicContact CD2-CG2 4.09Å; Y622-I676 HydrophobicContact CE2-CG2 4.48Å; F632-I676 HydrophobicContact CD1-CD1 3.44Å; F632-I676 VanDerWaalsContact CD1-CD1 3.44Å; F632-I676 HydrophobicContact CE1-CD1 3.47Å; F632-I676 VanDerWaalsContact CE1-CD1 3.47Å; F632-I676 HydrophobicContact CG-CD1 4.01Å; F632-I676 HydrophobicContact CZ-CD1 4.05Å; W633-I676 HydrophobicContact CZ2-CD1 4.44Å; F674-I676 HydrophobicContact CD1-CG1 4.15Å; F674-I676 HydrophobicContact CE1-CD1 4.04Å; F674-I676 HydrophobicContact CE1-CG1 3.63Å; I676-L695 WeakPolarHBondContact CA-O 3.3Å; I676-L697 HydrophobicContact CG2-CB 3.79Å; I676-L697 HydrophobicContact CG2-CD2 3.81Å; I676-L697 HydrophobicContact CG2-CG 4.48Å
677E96.4Very high86.8Confident46 Ų4654.5 Ų54.522%0.21528%0.284CS..EExtended strand (participates in β ladder)trans-125.4134-177.6-172.9157.7-174.300110.6K619 W679 R694 L695 D696 L697K619-E677 HydrophobicContact CB-CB 3.98Å; K619-E677 HydrophobicContact CB-CG 3.72Å; E677-W679 PolarHBondContact O-N 2.93Å; E677-R694 HydrophobicContact CB-CG 4.29Å; E677-R694 WeakPolarHBondContact OE2-CD 3.37Å; E677-R694 IonicContact OE2-CZ 3.97Å; E677-R694 IonicContact OE2-NE 2.79Å; E677-R694 PolarHBondContact OE2-NE 3.11Å; E677-R694 IonicContact OE2-NH1 3.66Å; E677-R694 PolarHBondContact OE2-NH1 2.87Å; E677-R694 IonicContact OE2-NH2 3.29Å; E677-L695 PolarHBondContact N-O 3.01Å; E677-D696 CarbonylContact O-C 3.59Å; E677-D696 WeakPolarHBondContact O-CA 3.3Å; E677-L697 PolarHBondContact O-N 3.06Å
678R95.9Very high87.6Confident137 Ų13755.8 Ų55.852%0.51730%0.295SS..EExtended strand (participates in β ladder)trans-62.8130.7174.4-177.5175.5-179.4-174.60110.3K619 G620 Y622K619-R678 PolarHBondContact O-N 3.05Å; G620-R678 WeakPolarHBondContact O-CB 3.47Å; G620-R678 WeakPolarHBondContact O-CD 3.45Å; Y622-R678 HydrophobicContact CD1-CB 3.88Å; Y622-R678 HydrophobicContact CD1-CG 4.36Å; Y622-R678 HydrophobicContact CD2-CB 3.88Å; Y622-R678 HydrophobicContact CE1-CB 3.58Å; Y622-R678 HydrophobicContact CE1-CG 3.63Å; Y622-R678 HydrophobicContact CE2-CB 3.6Å; Y622-R678 HydrophobicContact CE2-CG 4.18Å; Y622-R678 HydrophobicContact CG-CB 4.02Å; Y622-R678 VanDerWaalsContact CZ-CB 3.44Å
679W89.3Confident88.4Confident65 Ų6558.1 Ų58.125%0.24630%0.303CS..  trans-145.5143.8178.8175.476.8000112.6E677 M684 L685 R687 D696 L697 P698E677-W679 PolarHBondContact O-N 2.93Å; W679-M684 HydrophobicContact CH2-CB 3.92Å; W679-M684 HydrophobicContact CH2-CG 4.2Å; W679-M684 HydrophobicContact CH2-SD 3.17Å; W679-M684 WeakPolarHBondContact CH2-SD 3.35Å; W679-M684 HydrophobicContact CZ2-SD 3.59Å; W679-M684 VanDerWaalsContact CZ2-SD 3.59Å; W679-M684 HydrophobicContact CZ3-CB 3.63Å; W679-M684 HydrophobicContact CZ3-CG 4.32Å; W679-M684 HydrophobicContact CZ3-SD 3.73Å; W679-L685 VanDerWaalsContact CZ3-O 3.28Å; W679-L685 WeakPolarHBondContact CZ3-O 3.12Å; W679-R687 VanDerWaalsContact CE2-CZ 3.45Å; W679-R687 HydrophobicContact CH2-CG 4.26Å; W679-R687 VanDerWaalsContact CH2-NE 3.25Å; W679-R687 VanDerWaalsContact CZ2-NH2 3.28Å; W679-R687 HydrophobicContact CZ3-CG 4.17Å; W679-D696 HydrophobicContact CB-CB 3.64Å; W679-D696 HydrophobicContact CD2-CB 4.23Å; W679-D696 HydrophobicContact CE3-CB 4.4Å; W679-D696 HydrophobicContact CG-CB 3.89Å; W679-L697 PolarHBondContact N-O 3.24Å; W679-P698 HydrophobicContact CE3-CG 3.91Å; W679-P698 HydrophobicContact CZ3-CG 4.16Å; W679-P698 WeakPolarHBondContact O-CA 3.47Å
680G91Very high88.9Confident40 Ų4053.6 Ų53.641%0.41228%0.281SS..SBendtrans60.1-152.4171.100000115.2
681S91Very high88.8Confident46 Ų4653.4 Ų53.432%0.32228%0.275SS..  trans-120.2160-178.647.50000109.8D683 M684 P698S681-D683 WeakPolarHBondContact CB-OD1 3.42Å; S681-D683 PolarHBondContact O-N 2.52Å; S681-D683 PolarHBondContact OG-OD1 2.79Å; S681-M684 PolarHBondContact O-N 3.01Å; S681-M684 VanDerWaalsContact O-N 3.1Å; S681-M684 VanDerWaalsContact OG-CE 3.29Å; S681-M684 WeakPolarHBondContact OG-CE 3.33Å; S681-P698 WeakPolarHBondContact O-CB 3.48Å
682A90.1Very high88.9Confident28 Ų2851.9 Ų51.923%0.23126%0.264CS..THydrogen-bonded Turntrans-63-12.9-170.700000114.8Y700A682-Y700 HydrophobicContact CB-CD1 4.4Å; A682-Y700 WeakPolarHBondContact O-CD1 3.43Å; A682-Y700 WeakPolarHBondContact O-CE1 3.34Å
683D90Very high89.1Confident109 Ų10949.2 Ų49.258%0.58325%0.251SS*.THydrogen-bonded Turntrans-77.4-27.8175.556-61.3000113.6S681 K709S681-D683 WeakPolarHBondContact CB-OD1 3.42Å; S681-D683 PolarHBondContact O-N 2.52Å; S681-D683 PolarHBondContact OG-OD1 2.79Å; D683-K709 PolarHBondContact O-NZ 2.83Å
684M92.2Very high89.1Confident69 Ų6948.5 Ų48.534%0.3425%0.247SC..SBendtrans-73.5158.8-176.5-56.9-164.5-14100112.3W679 S681 P698 Y700W679-M684 HydrophobicContact CH2-CB 3.92Å; W679-M684 HydrophobicContact CH2-CG 4.2Å; W679-M684 HydrophobicContact CH2-SD 3.17Å; W679-M684 WeakPolarHBondContact CH2-SD 3.35Å; W679-M684 HydrophobicContact CZ2-SD 3.59Å; W679-M684 VanDerWaalsContact CZ2-SD 3.59Å; W679-M684 HydrophobicContact CZ3-CB 3.63Å; W679-M684 HydrophobicContact CZ3-CG 4.32Å; W679-M684 HydrophobicContact CZ3-SD 3.73Å; S681-M684 PolarHBondContact O-N 3.01Å; S681-M684 VanDerWaalsContact O-N 3.1Å; S681-M684 VanDerWaalsContact OG-CE 3.29Å; S681-M684 WeakPolarHBondContact OG-CE 3.33Å; M684-P698 HydrophobicContact CB-CG 4.38Å; M684-Y700 WeakPolarHBondContact O-CE1 3.23Å; M684-Y700 PolarHBondContact O-OH 2.78Å
685L92.4Very high89.1Confident67 Ų6748.5 Ų48.535%0.35125%0.247SC..PPolyproline II helixtrans-82.7152.1171.7-68.6176000111.3W679 K709 T712 A713W679-L685 VanDerWaalsContact CZ3-O 3.28Å; W679-L685 WeakPolarHBondContact CZ3-O 3.12Å; L685-K709 HydrophobicContact CD2-CB 4.3Å; L685-K709 HydrophobicContact CD2-CD 3.63Å; L685-T712 HydrophobicContact CD1-CG2 4.32Å; L685-T712 HydrophobicContact CD2-CG2 4.01Å; L685-A713 HydrophobicContact CB-CB 4.36Å
686P93.3Very high89.1Confident4 Ų449 Ų493%0.02625%0.249CC..PPolyproline II helixtrans-59.9149.6171-1934.1000110.9L695 D696 L697 Y700 K709 L710 A713P686-L695 HydrophobicContact CB-CD1 3.87Å; P686-D696 WeakPolarHBondContact CA-O 3.41Å; P686-L697 HydrophobicContact CB-CD1 4.45Å; P686-L697 HydrophobicContact CG-CD1 4.25Å; P686-Y700 WeakPolarHBondContact CD-OH 3.46Å; P686-Y700 HydrophobicContact CG-CE2 4Å; P686-Y700 WeakPolarHBondContact CG-OH 3.4Å; P686-K709 WeakPolarHBondContact CD-O 3.3Å; P686-L710 HydrophobicContact CG-CD1 4.38Å; P686-A713 HydrophobicContact CG-CB 4.44Å
687R89.5Confident89.1Confident110 Ų11049 Ų4942%0.41525%0.249SC..EExtended strand (participates in β ladder)trans-125.9150.1175-62.1-172.6-57.9160.112.3110.3W679 D696W679-R687 VanDerWaalsContact CE2-CZ 3.45Å; W679-R687 HydrophobicContact CH2-CG 4.26Å; W679-R687 VanDerWaalsContact CH2-NE 3.25Å; W679-R687 VanDerWaalsContact CZ2-NH2 3.28Å; W679-R687 HydrophobicContact CZ3-CG 4.17Å; R687-D696 HydrophobicContact CB-CB 4.21Å; R687-D696 PolarHBondContact N-O 2.84Å; R687-D696 IonicContact NH2-OD2 3.48Å; R687-D696 WeakPolarHBondContact O-CB 3.48Å; R687-D696 PolarHBondContact O-N 3.09Å
688A86.3Confident89.1Confident30 Ų3046.8 Ų46.825%0.24824%0.239CC..EExtended strand (participates in β ladder)trans-115.3140.7178.700000111.4F650 R694F650-A688 HydrophobicContact CD1-CB 4.07Å; F650-A688 HydrophobicContact CD2-CB 4.41Å; F650-A688 HydrophobicContact CE1-CB 3.89Å; F650-A688 HydrophobicContact CE2-CB 4.24Å; F650-A688 HydrophobicContact CG-CB 4.33Å; F650-A688 HydrophobicContact CZ-CB 3.98Å; F650-A688 WeakPolarHBondContact O-CB 3.49Å; A688-R694 CarbonylContact C-O 3.57Å; A688-R694 WeakPolarHBondContact CA-O 3.06Å
689H81.2Confident89Confident70 Ų7041.9 Ų41.932%0.32423%0.225SC..EExtended strand (participates in β ladder)trans-113.486.2165.8-54.2-95.5000107.9C691 F692 N693 R694 D696H689-C691 PolarHBondContact O-N 2.73Å; H689-F692 HydrophobicContact CB-CD2 3.97Å; H689-F692 CarbonylContact O-C 3.56Å; H689-F692 PolarHBondContact O-N 3.09Å; H689-N693 PolarHBondContact O-N 2.86Å; H689-N693 VanDerWaalsContact O-N 3.16Å; H689-R694 HydrophobicContact CB-CB 4.28Å; H689-R694 PolarHBondContact N-O 3.13Å; H689-R694 PolarHBondContact O-N 3.1Å; H689-D696 IonicContact CD2-OD1 3.95Å; H689-D696 PolarHBondContact CD2-OD1 2.73Å; H689-D696 IonicContact CD2-OD2 3.74Å; H689-D696 IonicContact CE1-OD2 2.77Å; H689-D696 VanDerWaalsContact NE2-CG 3.29Å; H689-D696 IonicContact NE2-OD1 3.5Å; H689-D696 PolarHBondContact NE2-OD1 2.84Å; H689-D696 IonicContact NE2-OD2 3.91Å; H689-D696 PolarHBondContact NE2-OD2 2.68Å
690T75.7Confident89.3Confident39 Ų3939 Ų3924%0.23921%0.214CC..G310 helixtrans-50.9-46.7-175.258.30000111.1R437 V651 F692 N693R437-T690 PolarHBondContact NH2-O 3.26Å; V651-T690 WeakPolarHBondContact O-CA 3.41Å; T690-F692 PolarHBondContact O-N 2.76Å; T690-N693 PolarHBondContact O-N 2.77Å; T690-N693 PolarHBondContact O-OD1 2.82Å; T690-N693 VanDerWaalsContact O-OD1 3.13Å
691C71Confident89.1Confident20 Ų2042.1 Ų42.114%0.13523%0.225CC..G310 helixtrans-47.6-31.3176.3-67.20000115G434 G667 S668 H689G434-C691 PolarHBondContact N-SG 3.39Å; G434-C691 VanDerWaalsContact N-SG 3.35Å; G667-C691 WeakPolarHBondContact CA-O 3.29Å; S668-C691 PolarHBondContact N-O 3.06Å; S668-C691 PolarHBondContact OG-O 2.81Å; H689-C691 PolarHBondContact O-N 2.73Å
692F81.8Confident89Confident77 Ų7743.2 Ų43.234%0.33823%0.23SC..G310 helixtrans-112.66.4-177.1-55.8-71.6000113.5Q672 H689 T690 R694Q672-F692 WeakPolarHBondContact CG-O 3.37Å; H689-F692 HydrophobicContact CB-CD2 3.97Å; H689-F692 CarbonylContact O-C 3.56Å; H689-F692 PolarHBondContact O-N 3.09Å; T690-F692 PolarHBondContact O-N 2.76Å; F692-R694 HydrophobicContact CB-CB 4.17Å; F692-R694 PolarHBondContact O-N 3.1Å
693N86Confident88.9Confident0 Ų043.2 Ų43.20%023%0.225CC..THydrogen-bonded Turntrans49.542.4-173-57.6-28.4000111.3R437 S652 Y666 Q672 F674 T675 H689 T690R437-N693 PolarHBondContact NH1-OD1 3.07Å; R437-N693 PolarHBondContact NH2-OD1 3.26Å; S652-N693 WeakPolarHBondContact CB-OD1 3.2Å; Y666-N693 PolarHBondContact O-ND2 2.89Å; Q672-N693 HydrophobicContact CG-CB 4.4Å; Q672-N693 PolarHBondContact O-ND2 2.64Å; F674-N693 CarbonylContact C-O 3.02Å; F674-N693 WeakPolarHBondContact CA-O 3.28Å; T675-N693 PolarHBondContact N-O 3.47Å; H689-N693 PolarHBondContact O-N 2.86Å; H689-N693 VanDerWaalsContact O-N 3.16Å; T690-N693 PolarHBondContact O-N 2.77Å; T690-N693 PolarHBondContact O-OD1 2.82Å; T690-N693 VanDerWaalsContact O-OD1 3.13Å
694R91Very high88.9Confident61 Ų6145.6 Ų45.623%0.2323%0.23CC..EExtended strand (participates in β ladder)trans-115.1126.8-170.8-176-169.4-55.8-167.1-2111.6T675 E677 A688 H689 F692 D696T675-R694 HydrophobicContact CG2-CG 4.18Å; T675-R694 CarbonylContact O-C 3.43Å; T675-R694 VanDerWaalsContact O-CA 3.25Å; T675-R694 WeakPolarHBondContact O-CA 3.36Å; E677-R694 HydrophobicContact CB-CG 4.29Å; E677-R694 WeakPolarHBondContact OE2-CD 3.37Å; E677-R694 IonicContact OE2-CZ 3.97Å; E677-R694 IonicContact OE2-NE 2.79Å; E677-R694 PolarHBondContact OE2-NE 3.11Å; E677-R694 IonicContact OE2-NH1 3.66Å; E677-R694 PolarHBondContact OE2-NH1 2.87Å; E677-R694 IonicContact OE2-NH2 3.29Å; A688-R694 CarbonylContact C-O 3.57Å; A688-R694 WeakPolarHBondContact CA-O 3.06Å; H689-R694 HydrophobicContact CB-CB 4.28Å; H689-R694 PolarHBondContact N-O 3.13Å; H689-R694 PolarHBondContact O-N 3.1Å; F692-R694 HydrophobicContact CB-CB 4.17Å; F692-R694 PolarHBondContact O-N 3.1Å; R694-D696 WeakPolarHBondContact CD-OD1 3.43Å
695L95.2Very high88.9Confident0 Ų044.9 Ų44.90%023%0.226CC..EExtended strand (participates in β ladder)trans-97.9112.7167.6179.764.3000109.2F632 F650 V651 F674 T675 I676 E677 P686 L697F632-L695 HydrophobicContact CD2-CD2 4.03Å; F632-L695 HydrophobicContact CE2-CD2 3.42Å; F632-L695 VanDerWaalsContact CE2-CD2 3.42Å; F632-L695 HydrophobicContact CZ-CD2 4Å; F650-L695 HydrophobicContact CD1-CD1 4.37Å; F650-L695 HydrophobicContact CE1-CD1 3.86Å; V651-L695 HydrophobicContact CG1-CB 3.96Å; V651-L695 HydrophobicContact CG2-CB 3.9Å; V651-L695 HydrophobicContact CG2-CD1 3.92Å; V651-L695 HydrophobicContact CG2-CD2 4.43Å; V651-L695 HydrophobicContact CG2-CG 4.3Å; F674-L695 HydrophobicContact CZ-CB 4.47Å; T675-L695 PolarHBondContact O-N 3.21Å; I676-L695 WeakPolarHBondContact CA-O 3.3Å; E677-L695 PolarHBondContact N-O 3.01Å; P686-L695 HydrophobicContact CB-CD1 3.87Å; L695-L697 HydrophobicContact CD2-CB 4.41Å; L695-L697 HydrophobicContact CD2-CD1 4.36Å; L695-L697 HydrophobicContact CG-CB 4.23Å; L695-L697 PolarHBondContact O-N 2.79Å
696D94.5Very high89Confident10 Ų1041.7 Ų41.75%0.05321%0.209CC..EExtended strand (participates in β ladder)trans-77102.6164.8-76.65.2000107.1E677 W679 P686 R687 H689 R694E677-D696 CarbonylContact O-C 3.59Å; E677-D696 WeakPolarHBondContact O-CA 3.3Å; W679-D696 HydrophobicContact CB-CB 3.64Å; W679-D696 HydrophobicContact CD2-CB 4.23Å; W679-D696 HydrophobicContact CE3-CB 4.4Å; W679-D696 HydrophobicContact CG-CB 3.89Å; P686-D696 WeakPolarHBondContact CA-O 3.41Å; R687-D696 HydrophobicContact CB-CB 4.21Å; R687-D696 PolarHBondContact N-O 2.84Å; R687-D696 IonicContact NH2-OD2 3.48Å; R687-D696 WeakPolarHBondContact O-CB 3.48Å; R687-D696 PolarHBondContact O-N 3.09Å; H689-D696 IonicContact CD2-OD1 3.95Å; H689-D696 PolarHBondContact CD2-OD1 2.73Å; H689-D696 IonicContact CD2-OD2 3.74Å; H689-D696 IonicContact CE1-OD2 2.77Å; H689-D696 VanDerWaalsContact NE2-CG 3.29Å; H689-D696 IonicContact NE2-OD1 3.5Å; H689-D696 PolarHBondContact NE2-OD1 2.84Å; H689-D696 IonicContact NE2-OD2 3.91Å; H689-D696 PolarHBondContact NE2-OD2 2.68Å; R694-D696 WeakPolarHBondContact CD-OD1 3.43Å
697L96.7Very high88.9Confident0 Ų043.3 Ų43.30%022%0.216CC..EExtended strand (participates in β ladder)trans-105.8119.1-174.5-174.464000109.9Y622 V628 F632 I676 E677 W679 P686 L695 Y700 L706Y622-L697 HydrophobicContact CE2-CB 4.18Å; Y622-L697 WeakPolarHBondContact CE2-O 3.33Å; Y622-L697 PolarHBondContact OH-O 2.94Å; V628-L697 HydrophobicContact CG2-CD2 3.85Å; V628-L697 HydrophobicContact CG2-CG 4.14Å; F632-L697 HydrophobicContact CB-CD2 4.11Å; F632-L697 HydrophobicContact CD2-CD2 4.22Å; F632-L697 HydrophobicContact CG-CD2 4.36Å; I676-L697 HydrophobicContact CG2-CB 3.79Å; I676-L697 HydrophobicContact CG2-CD2 3.81Å; I676-L697 HydrophobicContact CG2-CG 4.48Å; E677-L697 PolarHBondContact O-N 3.06Å; W679-L697 PolarHBondContact N-O 3.24Å; P686-L697 HydrophobicContact CB-CD1 4.45Å; P686-L697 HydrophobicContact CG-CD1 4.25Å; L695-L697 HydrophobicContact CD2-CB 4.41Å; L695-L697 HydrophobicContact CD2-CD1 4.36Å; L695-L697 HydrophobicContact CG-CB 4.23Å; L695-L697 PolarHBondContact O-N 2.79Å; L697-Y700 HydrophobicContact CD1-CD2 4.2Å; L697-Y700 HydrophobicContact CD1-CE2 3.92Å; L697-L706 HydrophobicContact CD1-CD1 4.46Å; L697-L706 HydrophobicContact CD2-CD1 4.31Å
698P96.5Very high89.1Confident0 Ų041.3 Ų41.30%022%0.218CC..  trans-64.6153.8172-26.236.3000114.1Y622 W679 S681 M684 Y700Y622-P698 VanDerWaalsContact OH-C 3.3Å; Y622-P698 PolarHBondContact OH-O 3.43Å; W679-P698 HydrophobicContact CE3-CG 3.91Å; W679-P698 HydrophobicContact CZ3-CG 4.16Å; W679-P698 WeakPolarHBondContact O-CA 3.47Å; S681-P698 WeakPolarHBondContact O-CB 3.48Å; M684-P698 HydrophobicContact CB-CG 4.38Å; P698-Y700 HydrophobicContact CB-CD1 4.39Å; P698-Y700 HydrophobicContact CB-CE1 3.84Å; P698-Y700 HydrophobicContact CB-CE2 4.1Å; P698-Y700 HydrophobicContact CG-CE1 4.35Å; P698-Y700 HydrophobicContact CG-CE2 4.28Å; P698-Y700 WeakPolarHBondContact CG-OH 3.3Å; P698-Y700 WeakPolarHBondContact O-CD2 3.49Å; P698-Y700 PolarHBondContact O-N 3.33Å
699P95Very high89.4Confident35 Ų3542.9 Ų42.923%0.22722%0.219CC..  trans-77.261.5-177.534.1-36.9000112Y622Y622-P699 WeakPolarHBondContact OH-CA 3.17Å
700Y94.2Very high90Very high5 Ų539.5 Ų39.52%0.0220%0.204CC..  trans-59.3140.2175.1-55.5-57.9000111A682 M684 P686 L697 P698 E705 L706 K709A682-Y700 HydrophobicContact CB-CD1 4.4Å; A682-Y700 WeakPolarHBondContact O-CD1 3.43Å; A682-Y700 WeakPolarHBondContact O-CE1 3.34Å; M684-Y700 WeakPolarHBondContact O-CE1 3.23Å; M684-Y700 PolarHBondContact O-OH 2.78Å; P686-Y700 WeakPolarHBondContact CD-OH 3.46Å; P686-Y700 HydrophobicContact CG-CE2 4Å; P686-Y700 WeakPolarHBondContact CG-OH 3.4Å; L697-Y700 HydrophobicContact CD1-CD2 4.2Å; L697-Y700 HydrophobicContact CD1-CE2 3.92Å; P698-Y700 HydrophobicContact CB-CD1 4.39Å; P698-Y700 HydrophobicContact CB-CE1 3.84Å; P698-Y700 HydrophobicContact CB-CE2 4.1Å; P698-Y700 HydrophobicContact CG-CE1 4.35Å; P698-Y700 HydrophobicContact CG-CE2 4.28Å; P698-Y700 WeakPolarHBondContact CG-OH 3.3Å; P698-Y700 WeakPolarHBondContact O-CD2 3.49Å; P698-Y700 PolarHBondContact O-N 3.33Å; Y700-E705 HydrophobicContact CD1-CG 3.76Å; Y700-E705 HydrophobicContact CG-CG 4.2Å; Y700-L706 HydrophobicContact CD2-CB 3.85Å; Y700-L706 HydrophobicContact CD2-CD1 4.23Å; Y700-L706 HydrophobicContact CD2-CG 3.84Å; Y700-L706 HydrophobicContact CG-CB 4.26Å; Y700-K709 HydrophobicContact CD1-CG 4.45Å; Y700-K709 HydrophobicContact CE1-CB 3.96Å; Y700-K709 HydrophobicContact CE1-CD 4.41Å; Y700-K709 HydrophobicContact CE1-CG 3.78Å; Y700-K709 HydrophobicContact CE2-CB 4.09Å
701T86.5Confident90.7Very high105 Ų10539.3 Ų39.364%0.64420%0.201SC*.SBendtrans-87.8-30.3-171.257.80000111.9E705T701-E705 PolarHBondContact N-OE2 3.37Å; T701-E705 PolarHBondContact OG1-OE2 3.26Å; T701-E705 VanDerWaalsContact OG1-OE2 3.06Å
702T89.2Confident91.5Very high69 Ų6940.6 Ų40.642%0.42321%0.209SC..SBendtrans-123157.1-175.770.50000112.6E705 L706T702-E705 WeakPolarHBondContact OG1-CB 3.38Å; T702-E705 PolarHBondContact OG1-N 2.74Å; T702-L706 PolarHBondContact O-N 3.4Å; T702-L706 VanDerWaalsContact O-N 3.16Å
703F88.3Confident91.8Very high27 Ų2737.3 Ų37.312%0.11820%0.196CC..Hα-helixtrans-59.7-45.1174168.5-106000112.1N631 K634 C635 E705 L706 K707N631-F703 PolarHBondContact ND2-N 2.89Å; K634-F703 HydrophobicContact CB-CD2 4.06Å; K634-F703 HydrophobicContact CB-CE2 4.02Å; K634-F703 HydrophobicContact CD-CD2 3.68Å; K634-F703 HydrophobicContact CD-CE2 3.94Å; K634-F703 HydrophobicContact CD-CG 4.07Å; K634-F703 HydrophobicContact CG-CD2 3.84Å; K634-F703 HydrophobicContact CG-CE2 3.66Å; K634-F703 HydrophobicContact CG-CZ 4.38Å; C635-F703 HydrophobicContact CB-CE2 4.01Å; F703-E705 PolarHBondContact O-N 2.75Å; F703-L706 PolarHBondContact O-N 3.01Å; F703-K707 HydrophobicContact CE1-CD 4.4Å; F703-K707 HydrophobicContact CZ-CD 4.15Å; F703-K707 WeakPolarHBondContact O-CB 3.3Å; F703-K707 PolarHBondContact O-N 3Å
704K90Very high91.5Very high159 Ų15937.8 Ų37.869%0.69120%0.198SC*.Hα-helixtrans-62.8-43.3-178.8-172.8174.5-177.6172.40112.4S708K704-S708 WeakPolarHBondContact O-CB 3.31Å; K704-S708 PolarHBondContact O-N 3.26Å
705E92.4Very high91Very high55 Ų5539.9 Ų39.926%0.25721%0.211SC..Hα-helixtrans-61.7-48.5175.9-178.8-178.5-149.600111.3Y700 T701 T702 F703 S708 K709Y700-E705 HydrophobicContact CD1-CG 3.76Å; Y700-E705 HydrophobicContact CG-CG 4.2Å; T701-E705 PolarHBondContact N-OE2 3.37Å; T701-E705 PolarHBondContact OG1-OE2 3.26Å; T701-E705 VanDerWaalsContact OG1-OE2 3.06Å; T702-E705 WeakPolarHBondContact OG1-CB 3.38Å; T702-E705 PolarHBondContact OG1-N 2.74Å; F703-E705 PolarHBondContact O-N 2.75Å; E705-S708 PolarHBondContact O-N 2.88Å; E705-K709 WeakPolarHBondContact O-CB 3.3Å; E705-K709 VanDerWaalsContact O-CG 3.28Å; E705-K709 WeakPolarHBondContact O-CG 3.49Å; E705-K709 PolarHBondContact O-N 3.18Å
706L94Very high89.9Confident0 Ų043.8 Ų43.80%023%0.231CC..Hα-helixtrans-59.8-49.3177.9-174.7154.6000111.4V628 N631 F632 C635 L697 Y700 T702 F703 S708 K709 L710V628-L706 HydrophobicContact CG2-CD1 3.98Å; V628-L706 WeakPolarHBondContact O-CD1 3.1Å; N631-L706 HydrophobicContact CB-CD1 3.94Å; F632-L706 HydrophobicContact CB-CD1 4.12Å; C635-L706 HydrophobicContact CB-CD2 3.95Å; L697-L706 HydrophobicContact CD1-CD1 4.46Å; L697-L706 HydrophobicContact CD2-CD1 4.31Å; Y700-L706 HydrophobicContact CD2-CB 3.85Å; Y700-L706 HydrophobicContact CD2-CD1 4.23Å; Y700-L706 HydrophobicContact CD2-CG 3.84Å; Y700-L706 HydrophobicContact CG-CB 4.26Å; T702-L706 PolarHBondContact O-N 3.4Å; T702-L706 VanDerWaalsContact O-N 3.16Å; F703-L706 PolarHBondContact O-N 3.01Å; L706-S708 PolarHBondContact O-N 2.85Å; L706-K709 PolarHBondContact O-N 2.88Å; L706-L710 HydrophobicContact CD2-CD2 4.34Å; L706-L710 WeakPolarHBondContact O-CB 3.47Å; L706-L710 PolarHBondContact O-N 2.64Å
707K92.4Very high88.5Confident38 Ų3846.4 Ų46.417%0.16525%0.25CS..Hα-helixtrans-58.5-50.6-179.4-178176.2-174.2-170.30111E319 F639 F703 L710 L711E319-K707 IonicContact OE1-NZ 3.33Å; E319-K707 PolarHBondContact OE1-NZ 3.37Å; E319-K707 IonicContact OE2-NZ 3.93Å; E319-K707 PolarHBondContact OE2-NZ 3.45Å; F639-K707 HydrophobicContact CE1-CG 4.3Å; F639-K707 HydrophobicContact CZ-CG 4.44Å; F703-K707 HydrophobicContact CE1-CD 4.4Å; F703-K707 HydrophobicContact CZ-CD 4.15Å; F703-K707 WeakPolarHBondContact O-CB 3.3Å; F703-K707 PolarHBondContact O-N 3Å; K707-L710 PolarHBondContact O-N 3.26Å; K707-L711 HydrophobicContact CG-CD1 4.06Å; K707-L711 WeakPolarHBondContact O-CB 3.33Å; K707-L711 WeakPolarHBondContact O-CG 3.43Å; K707-L711 PolarHBondContact O-N 2.97Å
708S92.2Very high86Confident67 Ų6752 Ų5247%0.46928%0.277SS..Hα-helixtrans-60-50.1179.4172.90000111.9K704 E705 L706 L710 L711 T712K704-S708 WeakPolarHBondContact O-CB 3.31Å; K704-S708 PolarHBondContact O-N 3.26Å; E705-S708 PolarHBondContact O-N 2.88Å; L706-S708 PolarHBondContact O-N 2.85Å; S708-L710 VanDerWaalsContact C-N 3.35Å; S708-L710 PolarHBondContact O-N 3.43Å; S708-L711 PolarHBondContact O-N 3.43Å; S708-T712 PolarHBondContact O-N 3.06Å; S708-T712 PolarHBondContact O-OG1 2.64Å
709K94Very high82.8Confident63 Ų6357.4 Ų57.427%0.27430%0.304SS..Hα-helixtrans-67-35.1-178.4-69.1-80-179.61680112.8D683 L685 P686 Y700 E705 L706 A713D683-K709 PolarHBondContact O-NZ 2.83Å; L685-K709 HydrophobicContact CD2-CB 4.3Å; L685-K709 HydrophobicContact CD2-CD 3.63Å; P686-K709 WeakPolarHBondContact CD-O 3.3Å; Y700-K709 HydrophobicContact CD1-CG 4.45Å; Y700-K709 HydrophobicContact CE1-CB 3.96Å; Y700-K709 HydrophobicContact CE1-CD 4.41Å; Y700-K709 HydrophobicContact CE1-CG 3.78Å; Y700-K709 HydrophobicContact CE2-CB 4.09Å; E705-K709 WeakPolarHBondContact O-CB 3.3Å; E705-K709 VanDerWaalsContact O-CG 3.28Å; E705-K709 WeakPolarHBondContact O-CG 3.49Å; E705-K709 PolarHBondContact O-N 3.18Å; L706-K709 PolarHBondContact O-N 2.88Å; K709-A713 WeakPolarHBondContact O-CB 3.22Å; K709-A713 PolarHBondContact O-N 2.86Å
710L92.6Very high79.5Confident0 Ų064.2 Ų64.20%033%0.331CS..Hα-helixtrans-66-47.5174.9-178.861.3000111.2F632 F639 V647 P686 L706 K707 S708 A713 I714F632-L710 HydrophobicContact CD2-CD2 4.39Å; F632-L710 HydrophobicContact CE2-CD2 4.19Å; F639-L710 HydrophobicContact CE2-CD2 4.25Å; V647-L710 HydrophobicContact CG2-CD2 4.49Å; P686-L710 HydrophobicContact CG-CD1 4.38Å; L706-L710 HydrophobicContact CD2-CD2 4.34Å; L706-L710 WeakPolarHBondContact O-CB 3.47Å; L706-L710 PolarHBondContact O-N 2.64Å; K707-L710 PolarHBondContact O-N 3.26Å; S708-L710 VanDerWaalsContact C-N 3.35Å; S708-L710 PolarHBondContact O-N 3.43Å; L710-A713 PolarHBondContact O-N 2.78Å; L710-I714 HydrophobicContact CD1-CD1 4.04Å; L710-I714 HydrophobicContact CD1-CG1 4.5Å; L710-I714 HydrophobicContact CG-CD1 3.92Å; L710-I714 WeakPolarHBondContact O-CD1 3.31Å; L710-I714 VanDerWaalsContact O-CG1 3.29Å; L710-I714 WeakPolarHBondContact O-CG1 3.36Å; L710-I714 PolarHBondContact O-N 2.93Å
711L90.2Very high76.3Confident35 Ų3568.2 Ų68.218%0.18336%0.359CS..Hα-helixtrans-60.3-47.3176-72.2172.9000111.3F639 M643 K707 S708 A713 I714 E715F639-L711 HydrophobicContact CE1-CD2 4.05Å; F639-L711 HydrophobicContact CE1-CG 4.45Å; F639-L711 HydrophobicContact CZ-CD2 3.74Å; F639-L711 HydrophobicContact CZ-CG 4.09Å; M643-L711 HydrophobicContact CE-CD2 3.69Å; M643-L711 HydrophobicContact CG-CD2 4.28Å; M643-L711 HydrophobicContact SD-CD2 3.55Å; M643-L711 VanDerWaalsContact SD-CD2 3.55Å; K707-L711 HydrophobicContact CG-CD1 4.06Å; K707-L711 WeakPolarHBondContact O-CB 3.33Å; K707-L711 WeakPolarHBondContact O-CG 3.43Å; K707-L711 PolarHBondContact O-N 2.97Å; S708-L711 PolarHBondContact O-N 3.43Å; L711-A713 VanDerWaalsContact C-N 3.3Å; L711-A713 PolarHBondContact O-N 2.77Å; L711-I714 PolarHBondContact O-N 2.82Å; L711-I714 VanDerWaalsContact O-N 3.09Å; L711-E715 WeakPolarHBondContact O-CB 3.27Å; L711-E715 WeakPolarHBondContact O-CG 3.29Å; L711-E715 PolarHBondContact O-N 2.84Å
712T89.6Confident73.2Confident47 Ų4766.7 Ų66.729%0.28836%0.364SS..Hα-helixtrans-56.8-42.6176.3-57.50000112L685 S708 N716L685-T712 HydrophobicContact CD1-CG2 4.32Å; L685-T712 HydrophobicContact CD2-CG2 4.01Å; S708-T712 PolarHBondContact O-N 3.06Å; S708-T712 PolarHBondContact O-OG1 2.64Å; T712-N716 WeakPolarHBondContact CG2-ND2 3.28Å; T712-N716 VanDerWaalsContact O-CB 3.31Å; T712-N716 WeakPolarHBondContact O-CB 3.33Å; T712-N716 PolarHBondContact O-N 3.05Å; T712-N716 PolarHBondContact O-ND2 2.8Å
713A87.1Confident70Confident8 Ų868.8 Ų68.87%0.06638%0.376CS..Hα-helixtrans-67.2-35.3178.300000113.2F650 L685 P686 K709 L710 L711 S717F650-A713 HydrophobicContact CE2-CB 4.42Å; F650-A713 HydrophobicContact CZ-CB 3.96Å; L685-A713 HydrophobicContact CB-CB 4.36Å; P686-A713 HydrophobicContact CG-CB 4.44Å; K709-A713 WeakPolarHBondContact O-CB 3.22Å; K709-A713 PolarHBondContact O-N 2.86Å; L710-A713 PolarHBondContact O-N 2.78Å; L711-A713 VanDerWaalsContact C-N 3.3Å; L711-A713 PolarHBondContact O-N 2.77Å; A713-S717 VanDerWaalsContact O-CB 3.31Å; A713-S717 WeakPolarHBondContact O-CB 3.45Å; A713-S717 PolarHBondContact O-N 2.78Å
714I80.6Confident67.1Low9 Ų979 Ų795%0.04643%0.432CS..Hα-helixtrans-69.8-52176.5-67.1164.1000110R646 V647 F650 L710 L711 N716 S717R646-I714 HydrophobicContact CB-CG2 3.91Å; V647-I714 HydrophobicContact CB-CD1 4.23Å; V647-I714 HydrophobicContact CG2-CD1 3.51Å; F650-I714 HydrophobicContact CB-CG1 3.99Å; F650-I714 HydrophobicContact CD1-CG1 4.16Å; F650-I714 HydrophobicContact CD2-CG1 4.46Å; F650-I714 HydrophobicContact CG-CG1 3.96Å; L710-I714 HydrophobicContact CD1-CD1 4.04Å; L710-I714 HydrophobicContact CD1-CG1 4.5Å; L710-I714 HydrophobicContact CG-CD1 3.92Å; L710-I714 WeakPolarHBondContact O-CD1 3.31Å; L710-I714 VanDerWaalsContact O-CG1 3.29Å; L710-I714 WeakPolarHBondContact O-CG1 3.36Å; L710-I714 PolarHBondContact O-N 2.93Å; L711-I714 PolarHBondContact O-N 2.82Å; L711-I714 VanDerWaalsContact O-N 3.09Å; I714-N716 VanDerWaalsContact C-N 3.3Å; I714-N716 PolarHBondContact O-N 3.36Å; I714-S717 PolarHBondContact O-N 2.92Å; I714-S717 VanDerWaalsContact O-N 3.08Å; I714-S717 PolarHBondContact O-OG 3.1Å
715E78.7Confident66Low106 Ų10675 Ų7550%0.49542%0.419SS..Hα-helixtrans-60.9-37.2-178.7-70.5165.5-175.800112.5L711 I719L711-E715 WeakPolarHBondContact O-CB 3.27Å; L711-E715 WeakPolarHBondContact O-CG 3.29Å; L711-E715 PolarHBondContact O-N 2.84Å; E715-I719 WeakPolarHBondContact O-CD1 3.24Å
716N73.7Confident64.6Low82 Ų8276.1 Ų76.144%0.43943%0.428SS..THydrogen-bonded Turntrans-87.4-3.9179-69.2-87.8000113.6T712 I714 E718T712-N716 WeakPolarHBondContact CG2-ND2 3.28Å; T712-N716 VanDerWaalsContact O-CB 3.31Å; T712-N716 WeakPolarHBondContact O-CB 3.33Å; T712-N716 PolarHBondContact O-N 3.05Å; T712-N716 PolarHBondContact O-ND2 2.8Å; I714-N716 VanDerWaalsContact C-N 3.3Å; I714-N716 PolarHBondContact O-N 3.36Å; N716-E718 VanDerWaalsContact C-N 3.35Å
717S63.4Low62.9Low64 Ų6480.3 Ų80.345%0.44845%0.452SS..THydrogen-bonded Turntrans-76.8-22.1175.567.50000113.1A713 I714A713-S717 VanDerWaalsContact O-CB 3.31Å; A713-S717 WeakPolarHBondContact O-CB 3.45Å; A713-S717 PolarHBondContact O-N 2.78Å; I714-S717 PolarHBondContact O-N 2.92Å; I714-S717 VanDerWaalsContact O-N 3.08Å; I714-S717 PolarHBondContact O-OG 3.1Å
718E45.8Very low61.2Low119 Ų11982.8 Ų82.856%0.55647%0.469SS*.SBendtrans-88.8-2.2-179.5-66.5-168.8156.400114.3N716N716-E718 VanDerWaalsContact C-N 3.35Å
719I28.5Very low59.3Low112 Ų11283.8 Ų83.857%0.57447%0.469SS*.  trans-113.72.3-159.3-57177.7000116E715 S721E715-I719 WeakPolarHBondContact O-CD1 3.24Å; I719-S721 PolarHBondContact O-N 2.74Å
720F25.1Very low56.9Low179 Ų17985.1 Ų85.179%0.78548%0.482SS*.  trans-81.232.9173.3-79.5-78.8000114.8V723F720-V723 HydrophobicContact CD1-CG2 4.35Å
721S27.2Very low54.4Low89 Ų8991.2 Ų91.262%0.62252%0.516SS*.SBendtrans-99.493.9160.360.50000109.2I719I719-S721 PolarHBondContact O-N 2.74Å
722G22.6Very low51.6Low72 Ų7295.5 Ų95.574%0.74254%0.542SS*.  trans118.667.6172.200000114.2
723V21.6Very low48.5Very low113 Ų11399.6 Ų99.669%0.68556%0.563SS**  trans-119.8115149.7-81.70000108.1F720F720-V723 HydrophobicContact CD1-CG2 4.35Å
724D27.3Very low45Very low242 Ų242107.9 Ų107.9100%1.29461%0.608SS**  trans74.70174-55.2-19.1000119.8

Retrieved 724 of 724 residues in 445.2 ms (Link to these results)