A0A061AD13_CAEEL Loading...

poly(A)-specific ribonuclease

AlphaFold DB , UniProt , Accession A0A061AD13, Species CAEEL (Caenorhabditis elegans), Gene ccr-4, Length 400 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M33.2Very low51.3Low230 Ų230131.1 Ų131.1100%1.13365%0.65SS**  090.10-73.1-177.8-160.600108.8R3M1-R3 PolarHBondContact O-N 2.6Å
2I36.2Very low54.8Low115 Ų115120.4 Ų120.459%0.5960%0.598SS**  trans-67108157.9-63.8172000103.5H4 A323I2-H4 PolarHBondContact O-N 3.24Å; I2-A323 HydrophobicContact CD1-CB 4.25Å
3R35.2Very low57.9Low228 Ų228113 Ų11386%0.8656%0.563SS**  trans-52.3129.9169-70.9-178.3179.6-172.3-0.3105.9M1 A5M1-R3 PolarHBondContact O-N 2.6Å; R3-A5 PolarHBondContact O-N 3.24Å
4H37.2Very low60.7Low188 Ų188104.9 Ų104.987%0.8752%0.523SS*.SBendtrans-3.1103.6175.7-66.9-79.9000112.6I2 D6I2-H4 PolarHBondContact O-N 3.24Å; H4-D6 PolarHBondContact O-N 2.76Å
5A44.2Very low63.3Low64 Ų6499.3 Ų99.353%0.52950%0.496SS..  trans-51.2109.6177.300000107.6R3 P7 I11R3-A5 PolarHBondContact O-N 3.24Å; A5-P7 VanDerWaalsContact O-CD 3.24Å; A5-P7 WeakPolarHBondContact O-CD 3.44Å; A5-P7 VanDerWaalsContact O-N 3.12Å; A5-I11 HydrophobicContact CB-CD1 4.49Å
6D49.4Very low65.5Low85 Ų8593.1 Ų93.146%0.45547%0.465SS..  trans-58.2114.2172.7-179.8-7000106.2H4 E8 R9H4-D6 PolarHBondContact O-N 2.76Å; D6-E8 PolarHBondContact O-N 3.09Å; D6-E8 PolarHBondContact OD1-N 2.76Å; D6-E8 VanDerWaalsContact OD1-N 3.16Å; D6-R9 HydrophobicContact CB-CB 4.25Å; D6-R9 PolarHBondContact O-N 3.07Å
7P51.4Low67.4Low130 Ų13087.6 Ų87.684%0.84444%0.438SS*.THydrogen-bonded Turntrans-61.1-14.6-175.23.7-1.7000112.9A5A5-P7 VanDerWaalsContact O-CD 3.24Å; A5-P7 WeakPolarHBondContact O-CD 3.44Å; A5-P7 VanDerWaalsContact O-N 3.12Å
8E55.3Low69.2Low161 Ų16182.8 Ų82.875%0.75241%0.414SS*.THydrogen-bonded Turntrans-92.7-6.1178.1-59.3-152.6154.300114.3D6 P10D6-E8 PolarHBondContact O-N 3.09Å; D6-E8 PolarHBondContact OD1-N 2.76Å; D6-E8 VanDerWaalsContact OD1-N 3.16Å; E8-P10 WeakPolarHBondContact O-CD 3.15Å
9R65.3Low70.7Confident126 Ų12678.5 Ų78.548%0.47539%0.392SS..SBendtrans-93.7116.8-179.5-119.6174.4170.3161.3-3.8111.3D6 I11 D178D6-R9 HydrophobicContact CB-CB 4.25Å; D6-R9 PolarHBondContact O-N 3.07Å; R9-I11 PolarHBondContact O-N 2.96Å; R9-D178 IonicContact CZ-OD1 3.99Å; R9-D178 IonicContact CZ-OD2 3.18Å; R9-D178 IonicContact NE-OD2 2.76Å; R9-D178 PolarHBondContact NE-OD2 3.34Å; R9-D178 IonicContact NH2-OD1 3.19Å; R9-D178 PolarHBondContact NH2-OD1 2.8Å; R9-D178 IonicContact NH2-OD2 2.78Å; R9-D178 PolarHBondContact NH2-OD2 3.15Å
10P72.7Confident72.1Confident35 Ų3574.6 Ų74.623%0.22737%0.373CS..PPolyproline II helixtrans-66.6123.8178.227.1-32.7000109.9E8 Y164 I174E8-P10 WeakPolarHBondContact O-CD 3.15Å; P10-Y164 HydrophobicContact CB-CD1 3.91Å; P10-Y164 HydrophobicContact CG-CD1 4.49Å; P10-I174 HydrophobicContact CG-CD1 4.39Å; P10-I174 HydrophobicContact CG-CG1 3.97Å
11I84.7Confident73.4Confident80 Ų8071 Ų7141%0.4136%0.355SS..PPolyproline II helixtrans-99.1122.5178-55.3177.5000108.1A5 R9 T13 A361A5-I11 HydrophobicContact CB-CD1 4.49Å; R9-I11 PolarHBondContact O-N 2.96Å; I11-T13 HydrophobicContact CB-CG2 4.26Å; I11-T13 HydrophobicContact CG2-CG2 3.71Å; I11-T13 PolarHBondContact O-N 3.43Å; I11-A361 HydrophobicContact CG2-CB 3.52Å
12A92.6Very high76.5Confident3 Ų360.1 Ų60.13%0.02530%0.301CS..  trans-70.5113.3171.300000109V163 Y164 V180 A361 I362A12-V163 WeakPolarHBondContact CA-O 3.25Å; A12-V163 HydrophobicContact CB-CB 4.3Å; A12-V163 HydrophobicContact CB-CG2 3.61Å; A12-Y164 HydrophobicContact CB-CD1 3.88Å; A12-Y164 HydrophobicContact CB-CE1 3.59Å; A12-Y164 HydrophobicContact CB-CE2 4.28Å; A12-Y164 HydrophobicContact CB-CG 4.4Å; A12-V180 HydrophobicContact CB-CG2 3.53Å; A12-A361 CarbonylContact O-C 3.55Å; A12-A361 VanDerWaalsContact O-CA 3.32Å; A12-A361 WeakPolarHBondContact O-CA 3.48Å; A12-I362 HydrophobicContact CB-CB 4.16Å; A12-I362 HydrophobicContact CB-CD1 4.19Å; A12-I362 PolarHBondContact O-N 2.89Å
13T95.5Very high79.3Confident24 Ų2454.7 Ų54.715%0.14727%0.273CS..EExtended strand (participates in β ladder)trans-125.3150.1-179.365.30000111.7I11 V163 L325 Y360 A361I11-T13 HydrophobicContact CB-CG2 4.26Å; I11-T13 HydrophobicContact CG2-CG2 3.71Å; I11-T13 PolarHBondContact O-N 3.43Å; T13-V163 PolarHBondContact N-O 3.18Å; T13-L325 HydrophobicContact CG2-CD1 3.66Å; T13-Y360 VanDerWaalsContact CA-O 3.24Å; T13-Y360 WeakPolarHBondContact CA-O 3.34Å; T13-A361 HydrophobicContact CG2-CB 4.31Å
14F97.8Very high82.2Confident0 Ų047.1 Ų47.10%025%0.25CS..EExtended strand (participates in β ladder)trans-151.8161.617173.3-78.1000111.2D59 V60 F117 L185 L234 L322 Y360 I362F14-D59 WeakPolarHBondContact CA-OD2 3.11Å; F14-D59 HydrophobicContact CB-CB 3.99Å; F14-D59 WeakPolarHBondContact CB-OD2 3.45Å; F14-V60 HydrophobicContact CD2-CG2 4.22Å; F14-V60 HydrophobicContact CE2-CG2 4.44Å; F14-F117 HydrophobicContact CB-CE2 4.4Å; F14-F117 HydrophobicContact CB-CZ 3.89Å; F14-F117 HydrophobicContact CD2-CZ 4.12Å; F14-F117 AromaticContact CG-CZ 3.93Å; F14-F117 HydrophobicContact CG-CZ 3.93Å; F14-L185 HydrophobicContact CE1-CD2 4.4Å; F14-L185 HydrophobicContact CE2-CD2 4Å; F14-L185 HydrophobicContact CZ-CD1 4.2Å; F14-L185 HydrophobicContact CZ-CD2 3.88Å; F14-L234 HydrophobicContact CE2-CD1 3.48Å; F14-L234 VanDerWaalsContact CE2-CD1 3.48Å; F14-L234 HydrophobicContact CZ-CD1 3.66Å; F14-L322 HydrophobicContact CE1-CD2 3.77Å; F14-L322 HydrophobicContact CZ-CD1 4.49Å; F14-L322 HydrophobicContact CZ-CD2 4.06Å; F14-Y360 PolarHBondContact N-O 2.8Å; F14-Y360 PolarHBondContact O-N 3.48Å; F14-I362 HydrophobicContact CD1-CD1 3.83Å; F14-I362 HydrophobicContact CD1-CG1 3.77Å; F14-I362 HydrophobicContact CE1-CD1 4.02Å; F14-I362 HydrophobicContact CE1-CG1 3.62Å
15T98.4Very high84.9Confident20 Ų2043.3 Ų43.312%0.12323%0.231CC..EExtended strand (participates in β ladder)trans-111.9147.9176.852.60000112A58 D59 V60 M357 A358 Q359T15-A58 VanDerWaalsContact OG1-CA 3.28Å; T15-A58 WeakPolarHBondContact OG1-CA 3.1Å; T15-D59 PolarHBondContact N-OD2 2.92Å; T15-D59 WeakPolarHBondContact O-CB 3.47Å; T15-D59 PolarHBondContact O-N 2.93Å; T15-D59 VanDerWaalsContact O-N 3.11Å; T15-D59 PolarHBondContact OG1-N 2.86Å; T15-D59 PolarHBondContact OG1-OD2 2.85Å; T15-V60 PolarHBondContact O-N 2.94Å; T15-M357 HydrophobicContact CG2-CE 3.69Å; T15-A358 CarbonylContact C-O 3.59Å; T15-A358 WeakPolarHBondContact CA-O 3.1Å; T15-Q359 HydrophobicContact CG2-CB 3.98Å; T15-Q359 HydrophobicContact CG2-CG 3.87Å
16V98.8Very high87.3Confident0 Ų043.8 Ų43.80%022%0.22CC..EExtended strand (participates in β ladder)trans-127.4130.6175.858.70000110.3V60 L234 I315 M357 A358 Y360V16-V60 CarbonylContact C-O 3.53Å; V16-V60 VanDerWaalsContact CA-O 3.27Å; V16-V60 WeakPolarHBondContact CA-O 3.24Å; V16-V60 HydrophobicContact CB-CB 4.42Å; V16-V60 HydrophobicContact CG2-CB 4.3Å; V16-V60 HydrophobicContact CG2-CG1 4.23Å; V16-L234 HydrophobicContact CB-CD1 4.17Å; V16-L234 HydrophobicContact CG1-CD1 4.24Å; V16-L234 HydrophobicContact CG1-CD2 4.42Å; V16-L234 HydrophobicContact CG2-CD1 4.25Å; V16-I315 HydrophobicContact CG1-CD1 4.28Å; V16-I315 HydrophobicContact CG1-CG2 3.86Å; V16-M357 CarbonylContact O-C 3.59Å; V16-M357 WeakPolarHBondContact O-CA 3.36Å; V16-M357 VanDerWaalsContact O-CG 3.28Å; V16-M357 WeakPolarHBondContact O-CG 2.9Å; V16-A358 HydrophobicContact CG1-CB 4.28Å; V16-A358 PolarHBondContact N-O 3.01Å; V16-A358 PolarHBondContact O-N 2.86Å; V16-Y360 HydrophobicContact CG1-CD2 4.01Å; V16-Y360 HydrophobicContact CG1-CE2 3.7Å
17L98.8Very high89.5Confident0 Ų040.2 Ų40.20%020%0.202CC..EExtended strand (participates in β ladder)trans-108.9131.7174.4-178.471.8000109.4I53 Y56 A58 V60 I61 T62 P355 M357L17-I53 HydrophobicContact CD2-CG1 4.42Å; L17-Y56 HydrophobicContact CD1-CD2 3.73Å; L17-Y56 HydrophobicContact CD1-CE2 4.21Å; L17-Y56 HydrophobicContact CD1-CG 4.12Å; L17-Y56 HydrophobicContact CD2-CD2 4.04Å; L17-A58 HydrophobicContact CB-CB 3.53Å; L17-V60 PolarHBondContact N-O 2.89Å; L17-I61 HydrophobicContact CB-CG1 4.26Å; L17-I61 HydrophobicContact CB-CG2 4.44Å; L17-I61 HydrophobicContact CD2-CG1 4.28Å; L17-I61 HydrophobicContact CD2-CG2 4.05Å; L17-I61 CarbonylContact O-C 3.48Å; L17-I61 WeakPolarHBondContact O-CA 3.32Å; L17-T62 PolarHBondContact O-N 3.34Å; L17-T62 PolarHBondContact O-OG1 3.05Å; L17-P355 HydrophobicContact CD1-CB 3.78Å; L17-M357 HydrophobicContact CD1-CB 3.96Å; L17-M357 HydrophobicContact CD1-CG 4.43Å
18C98.8Very high91.6Very high1 Ų136.8 Ų36.81%0.00718%0.179CC..EExtended strand (participates in β ladder)trans-119.4127.5170-176.90000109.9T62 C236 G237 I315 I356C18-T62 WeakPolarHBondContact CA-O 3.39Å; C18-T62 WeakPolarHBondContact CA-OG1 3.43Å; C18-C236 HydrophobicContact CB-CB 3.97Å; C18-G237 VanDerWaalsContact SG-CA 3.54Å; C18-G237 PolarHBondContact SG-N 3.08Å; C18-I315 HydrophobicContact CB-CD1 4.18Å; C18-I315 HydrophobicContact CB-CG1 3.82Å; C18-I356 HydrophobicContact CB-CD1 4.21Å; C18-I356 HydrophobicContact CB-CG1 3.79Å; C18-I356 PolarHBondContact N-O 3.35Å; C18-I356 PolarHBondContact O-N 3.14Å
19Y98.8Very high93.4Very high1 Ų132.6 Ų32.60%0.00416%0.164CC..EExtended strand (participates in β ladder)trans-153.5118.2-174.1-173.3-156.5000113.2V21 I49 E52 T62 L63 Q64 S351 H353 P355Y19-V21 HydrophobicContact CD1-CG1 3.79Å; Y19-V21 HydrophobicContact CE1-CG1 4.07Å; Y19-V21 HydrophobicContact CG-CG1 4.22Å; Y19-I49 HydrophobicContact CE1-CG2 4.31Å; Y19-E52 VanDerWaalsContact CE1-OE2 3.24Å; Y19-E52 WeakPolarHBondContact CE1-OE2 3.44Å; Y19-E52 PolarHBondContact OH-OE2 2.56Å; Y19-T62 PolarHBondContact N-O 2.89Å; Y19-L63 HydrophobicContact CD1-CD2 4.41Å; Y19-L63 VanDerWaalsContact O-CA 3.26Å; Y19-L63 WeakPolarHBondContact O-CA 3.48Å; Y19-Q64 VanDerWaalsContact C-OE1 3.27Å; Y19-Q64 PolarHBondContact O-N 3.42Å; Y19-Q64 VanDerWaalsContact O-N 3.12Å; Y19-Q64 PolarHBondContact O-OE1 2.82Å; Y19-S351 VanDerWaalsContact OH-CB 3.29Å; Y19-S351 WeakPolarHBondContact OH-CB 3.44Å; Y19-H353 WeakPolarHBondContact CE2-O 3.4Å; Y19-P355 HydrophobicContact CD1-CB 4.34Å; Y19-P355 HydrophobicContact CD2-CB 3.98Å; Y19-P355 HydrophobicContact CD2-CG 4.47Å; Y19-P355 HydrophobicContact CE2-CB 4.48Å; Y19-P355 HydrophobicContact CE2-CG 4.49Å; Y19-P355 HydrophobicContact CG-CB 3.91Å
20N98.8Very high94.7Very high0 Ų034 Ų340%018%0.181CC..EExtended strand (participates in β ladder)trans-78.6118.4163.2-178.3-19.1000108.8L22 Q64 E65 D238 S351 H353N20-L22 PolarHBondContact OD1-N 2.71Å; N20-L22 VanDerWaalsContact OD1-N 3.07Å; N20-Q64 HydrophobicContact CB-CB 4.08Å; N20-E65 PolarHBondContact ND2-OE1 2.89Å; N20-E65 VanDerWaalsContact OD1-CB 3.3Å; N20-E65 WeakPolarHBondContact OD1-CB 3.33Å; N20-E65 WeakPolarHBondContact OD1-CG 3.29Å; N20-E65 PolarHBondContact OD1-OE1 3.37Å; N20-D238 PolarHBondContact ND2-OD2 2.79Å; N20-S351 WeakPolarHBondContact O-CB 3.38Å; N20-S351 PolarHBondContact O-OG 3.44Å; N20-H353 HydrophobicContact CB-CB 4.01Å
21V98.6Very high95.6Very high0 Ų037.4 Ų37.40%019%0.194CC..  trans-90.40.5-170.9-57.70000114.4Y19 R45 I49 L63 Q64 E65 V66 F75Y19-V21 HydrophobicContact CD1-CG1 3.79Å; Y19-V21 HydrophobicContact CE1-CG1 4.07Å; Y19-V21 HydrophobicContact CG-CG1 4.22Å; V21-R45 PolarHBondContact O-NH1 3.37Å; V21-I49 HydrophobicContact CB-CD1 4.23Å; V21-I49 HydrophobicContact CB-CG2 4.2Å; V21-I49 HydrophobicContact CG1-CG2 3.92Å; V21-L63 HydrophobicContact CG1-CD1 4.36Å; V21-L63 HydrophobicContact CG1-CD2 4.03Å; V21-Q64 WeakPolarHBondContact CG2-O 3.28Å; V21-Q64 PolarHBondContact N-O 3.46Å; V21-Q64 VanDerWaalsContact N-O 3.1Å; V21-E65 WeakPolarHBondContact CG2-O 3.46Å; V21-V66 HydrophobicContact CG2-CG2 4.26Å; V21-F75 HydrophobicContact CG2-CZ 4.1Å
22L98.4Very high96.2Very high1 Ų133.7 Ų33.71%0.00518%0.175CC..  trans53.7100.1-172.3179.864.2000112.4N20 A27 Y32 R45 E65 P345N20-L22 PolarHBondContact OD1-N 2.71Å; N20-L22 VanDerWaalsContact OD1-N 3.07Å; L22-A27 HydrophobicContact CD2-CB 4.05Å; L22-A27 HydrophobicContact CG-CB 4.18Å; L22-Y32 HydrophobicContact CD1-CE2 4.1Å; L22-Y32 WeakPolarHBondContact CD1-OH 3.47Å; L22-Y32 HydrophobicContact CD2-CE2 3.93Å; L22-R45 VanDerWaalsContact O-CZ 3.31Å; L22-R45 PolarHBondContact O-NH1 3Å; L22-R45 PolarHBondContact O-NH2 2.98Å; L22-E65 WeakPolarHBondContact CA-OE2 3.37Å; L22-P345 HydrophobicContact CD2-CG 3.33Å
23C96.1Very high96.4Very high1 Ų137.6 Ų37.61%0.00720%0.202CC..  trans-62.7155.8179.1650000111.8K25 Y26 A27 E65 E67 D106C23-K25 PolarHBondContact O-N 3.03Å; C23-Y26 PolarHBondContact O-N 3.16Å; C23-Y26 WeakPolarHBondContact SG-CD2 3.45Å; C23-Y26 VanDerWaalsContact SG-CG 3.57Å; C23-A27 PolarHBondContact O-N 3.37Å; C23-E65 HydrophobicContact CB-CB 4.05Å; C23-E65 WeakPolarHBondContact CB-O 3.2Å; C23-E65 PolarHBondContact N-OE2 3.25Å; C23-E65 PolarHBondContact SG-OE2 3.22Å; C23-E65 VanDerWaalsContact SG-OE2 3.39Å; C23-E67 HydrophobicContact CB-CG 3.75Å; C23-D106 HydrophobicContact CB-CB 4.07Å
24D95.6Very high96.4Very high70 Ų7038.9 Ų38.937%0.37420%0.204SC..THydrogen-bonded Turntrans-62.8-36.1-178-170.250.4000111.2Y26 A27 W42 E67D24-Y26 PolarHBondContact O-N 3.39Å; D24-Y26 VanDerWaalsContact O-N 3.16Å; D24-A27 PolarHBondContact O-N 3.34Å; D24-A27 VanDerWaalsContact O-N 3.16Å; D24-W42 HydrophobicContact CB-CB 4.04Å; D24-W42 HydrophobicContact CB-CD2 4.4Å; D24-W42 HydrophobicContact CB-CE3 4.3Å; D24-W42 HydrophobicContact CB-CG 4.32Å; D24-W42 WeakPolarHBondContact OD1-CB 3.4Å; D24-E67 WeakPolarHBondContact CB-OE1 3.34Å; D24-E67 PolarHBondContact N-OE1 3.01Å
25K93.6Very high96.3Very high108 Ų10839.1 Ų39.147%0.4721%0.206SC..THydrogen-bonded Turntrans-54.7-34.2176.8-172.8172.1-175.8171.70114.2C23 E67C23-K25 PolarHBondContact O-N 3.03Å; K25-E67 PolarHBondContact N-OE1 2.73Å
26Y93.7Very high96.3Very high73 Ų7340.7 Ų40.729%0.28622%0.217SC..THydrogen-bonded Turntrans-96.2-16.2-178.9-59.7-31.1000113.2C23 D24 T28 Q31 Y32 E65C23-Y26 PolarHBondContact O-N 3.16Å; C23-Y26 WeakPolarHBondContact SG-CD2 3.45Å; C23-Y26 VanDerWaalsContact SG-CG 3.57Å; D24-Y26 PolarHBondContact O-N 3.39Å; D24-Y26 VanDerWaalsContact O-N 3.16Å; Y26-T28 PolarHBondContact O-N 3.07Å; Y26-Q31 PolarHBondContact O-OE1 3.33Å; Y26-Y32 WeakPolarHBondContact O-CE2 3.47Å; Y26-E65 WeakPolarHBondContact CD2-OE2 3.29Å
27A95.8Very high96.2Very high10 Ų1044.3 Ų44.38%0.08324%0.242CC..  trans-73.756.8178.700000113.8L22 C23 D24L22-A27 HydrophobicContact CD2-CB 4.05Å; L22-A27 HydrophobicContact CG-CB 4.18Å; C23-A27 PolarHBondContact O-N 3.37Å; D24-A27 PolarHBondContact O-N 3.34Å; D24-A27 VanDerWaalsContact O-N 3.16Å
28T95.1Very high96.1Very high59 Ų5951.2 Ų51.236%0.36227%0.268SS..  trans-92150.4-175.473.10000112.8Y26 N30 Q31 Y32Y26-T28 PolarHBondContact O-N 3.07Å; T28-N30 PolarHBondContact O-N 2.73Å; T28-Q31 PolarHBondContact O-N 3Å; T28-Q31 PolarHBondContact OG1-N 3.47Å; T28-Y32 PolarHBondContact O-N 3.28Å
29V92.9Very high96.1Very high73 Ų7351.2 Ų51.244%0.44227%0.268SS..THydrogen-bonded Turntrans-62.5-26.1175.5-179.20000112.1Y32 S33 L40V29-Y32 CarbonylContact O-C 3.54Å; V29-S33 WeakPolarHBondContact O-CA 3.19Å; V29-S33 WeakPolarHBondContact O-CB 3.28Å; V29-S33 PolarHBondContact O-N 2.79Å; V29-S33 VanDerWaalsContact O-N 3.09Å; V29-L40 HydrophobicContact CG2-CD1 4.2Å
30N92.7Very high96Very high156 Ų15651.4 Ų51.483%0.83427%0.269SS*.THydrogen-bonded Turntrans-69-42177.1-69.8-11.2000111.6T28T28-N30 PolarHBondContact O-N 2.73Å
31Q93Very high95.9Very high105 Ų10555.3 Ų55.349%0.49129%0.29SS..THydrogen-bonded Turntrans-79.7-35.1179.8-172.8167.6-4.800112.1Y26 T28Y26-Q31 PolarHBondContact O-OE1 3.33Å; T28-Q31 PolarHBondContact O-N 3Å; T28-Q31 PolarHBondContact OG1-N 3.47Å
32Y96.7Very high95.9Very high2 Ų255.9 Ų55.91%0.00829%0.292CS..  trans-119.451.8-175.9-54.6-77.3000111.5L22 Y26 T28 V29 Y34 C35 L40 T305 P345 D352L22-Y32 HydrophobicContact CD1-CE2 4.1Å; L22-Y32 WeakPolarHBondContact CD1-OH 3.47Å; L22-Y32 HydrophobicContact CD2-CE2 3.93Å; Y26-Y32 WeakPolarHBondContact O-CE2 3.47Å; T28-Y32 PolarHBondContact O-N 3.28Å; V29-Y32 CarbonylContact O-C 3.54Å; Y32-Y34 HydrophobicContact CD1-CE2 4.44Å; Y32-Y34 AromaticContact CD1-CZ 3.92Å; Y32-Y34 WeakPolarHBondContact CD1-OH 3.25Å; Y32-Y34 PolarHBondContact O-N 3Å; Y32-Y34 VanDerWaalsContact O-N 3.09Å; Y32-C35 PolarHBondContact O-N 3.44Å; Y32-L40 HydrophobicContact CD2-CD2 4.25Å; Y32-L40 HydrophobicContact CG-CD2 4.15Å; Y32-T305 HydrophobicContact CE1-CG2 4.02Å; Y32-P345 HydrophobicContact CD1-CG 4.41Å; Y32-D352 HydrophobicContact CE1-CB 3.74Å; Y32-D352 PolarHBondContact OH-OD2 2.71Å
33S95.9Very high95.9Very high86 Ų8661.6 Ų61.660%0.60132%0.319SS*.THydrogen-bonded Turntrans-61.4-20-174.660.90000114.8V29V29-S33 WeakPolarHBondContact O-CA 3.19Å; V29-S33 WeakPolarHBondContact O-CB 3.28Å; V29-S33 PolarHBondContact O-N 2.79Å; V29-S33 VanDerWaalsContact O-N 3.09Å
34Y95.8Very high96Very high50 Ų5065.5 Ų65.520%0.19633%0.334CS..THydrogen-bonded Turntrans-81.6-14.1174.149.4-92.4000113.7Y32 T305 L306 G343 F344Y32-Y34 HydrophobicContact CD1-CE2 4.44Å; Y32-Y34 AromaticContact CD1-CZ 3.92Å; Y32-Y34 WeakPolarHBondContact CD1-OH 3.25Å; Y32-Y34 PolarHBondContact O-N 3Å; Y32-Y34 VanDerWaalsContact O-N 3.09Å; Y34-T305 WeakPolarHBondContact OH-CA 3.37Å; Y34-T305 WeakPolarHBondContact OH-CB 3.49Å; Y34-L306 HydrophobicContact CD1-CB 3.73Å; Y34-L306 HydrophobicContact CD1-CD2 4.15Å; Y34-L306 HydrophobicContact CD1-CG 4.47Å; Y34-L306 HydrophobicContact CE1-CB 3.41Å; Y34-L306 VanDerWaalsContact CE1-CB 3.41Å; Y34-L306 PolarHBondContact OH-N 3.08Å; Y34-G343 VanDerWaalsContact CE2-C 3.4Å; Y34-F344 PolarHBondContact OH-O 2.91Å
35C97.3Very high96.1Very high6 Ų662.1 Ų62.14%0.04132%0.316CS..SBendtrans-97.7126.4179.5-169.80000110.3Y32 S37 L40 P345Y32-C35 PolarHBondContact O-N 3.44Å; C35-S37 PolarHBondContact O-N 2.78Å; C35-L40 HydrophobicContact CB-CD1 4.18Å; C35-L40 HydrophobicContact CB-CD2 3.79Å; C35-L40 HydrophobicContact CB-CG 3.81Å; C35-P345 WeakPolarHBondContact CB-O 3.26Å; C35-P345 PolarHBondContact SG-O 2.95Å; C35-P345 VanDerWaalsContact SG-O 3.39Å
36P97.1Very high96.3Very high52 Ų5259.2 Ų59.234%0.33830%0.304SS..  trans-57.1139.2176.3-24.633.6000112.2W38 A39 L40 P347P36-W38 HydrophobicContact CB-CD2 4.4Å; P36-W38 HydrophobicContact CB-CG 4.26Å; P36-W38 HydrophobicContact CB-CZ2 4.44Å; P36-W38 HydrophobicContact CG-CZ2 4.48Å; P36-W38 PolarHBondContact O-N 2.92Å; P36-W38 VanDerWaalsContact O-N 3.07Å; P36-A39 HydrophobicContact CB-CB 4.48Å; P36-A39 WeakPolarHBondContact O-CA 3.28Å; P36-A39 WeakPolarHBondContact O-CB 3.35Å; P36-A39 PolarHBondContact O-N 2.94Å; P36-L40 PolarHBondContact O-N 3.34Å; P36-P347 HydrophobicContact CG-CG 4.47Å
37S96.9Very high96.5Very high76 Ų7657.9 Ų57.953%0.53131%0.312SS..Hα-helixtrans-57.2-31.1-176.2-48.80000114C35 A39 L40 N41C35-S37 PolarHBondContact O-N 2.78Å; S37-A39 VanDerWaalsContact C-N 3.31Å; S37-A39 PolarHBondContact O-N 3.02Å; S37-L40 PolarHBondContact O-N 3.19Å; S37-N41 PolarHBondContact O-N 2.76Å
38W97.6Very high96.6Very high146 Ų14659.5 Ų59.555%0.55332%0.319SS*.Hα-helixtrans-68.7-29.6175.465.2-100.2000112.9P36 Y44 P347P36-W38 HydrophobicContact CB-CD2 4.4Å; P36-W38 HydrophobicContact CB-CG 4.26Å; P36-W38 HydrophobicContact CB-CZ2 4.44Å; P36-W38 HydrophobicContact CG-CZ2 4.48Å; P36-W38 PolarHBondContact O-N 2.92Å; P36-W38 VanDerWaalsContact O-N 3.07Å; W38-Y44 HydrophobicContact CE3-CD2 4.28Å; W38-Y44 HydrophobicContact CE3-CE1 4.47Å; W38-Y44 HydrophobicContact CE3-CE2 4.24Å; W38-Y44 HydrophobicContact CE3-CG 4.42Å; W38-Y44 HydrophobicContact CZ3-CD1 4.41Å; W38-Y44 HydrophobicContact CZ3-CD2 4.24Å; W38-Y44 AromaticContact CZ3-CE1 3.93Å; W38-Y44 HydrophobicContact CZ3-CE1 3.93Å; W38-Y44 AromaticContact CZ3-CE2 3.74Å; W38-Y44 HydrophobicContact CZ3-CE2 3.74Å; W38-Y44 AromaticContact CZ3-CZ 3.58Å; W38-Y44 VanDerWaalsContact O-CB 3.31Å; W38-Y44 WeakPolarHBondContact O-CB 3.48Å; W38-P347 HydrophobicContact CH2-CB 3.7Å; W38-P347 HydrophobicContact CH2-CG 3.83Å; W38-P347 HydrophobicContact CZ2-CB 4.31Å; W38-P347 HydrophobicContact CZ2-CG 3.94Å; W38-P347 HydrophobicContact CZ3-CB 4.44Å
39A97.2Very high96.8Very high1 Ų156.7 Ų56.71%0.00830%0.301CS..Hα-helixtrans-83.9-26.3176.900000111.8P36 S37 Y44 R45 P347P36-A39 HydrophobicContact CB-CB 4.48Å; P36-A39 WeakPolarHBondContact O-CA 3.28Å; P36-A39 WeakPolarHBondContact O-CB 3.35Å; P36-A39 PolarHBondContact O-N 2.94Å; S37-A39 VanDerWaalsContact C-N 3.31Å; S37-A39 PolarHBondContact O-N 3.02Å; A39-Y44 HydrophobicContact CB-CD1 4.37Å; A39-Y44 HydrophobicContact CB-CE1 4.33Å; A39-R45 WeakPolarHBondContact O-CD 3.11Å; A39-R45 WeakPolarHBondContact O-CG 3.29Å; A39-P347 HydrophobicContact CB-CG 4.05Å
40L97.3Very high97Very high5 Ų553.7 Ų53.73%0.02628%0.283CS..Hα-helixtrans-74-30.2170.4-72.3175.3000113V29 Y32 C35 P36 S37 W42 R45 P345V29-L40 HydrophobicContact CG2-CD1 4.2Å; Y32-L40 HydrophobicContact CD2-CD2 4.25Å; Y32-L40 HydrophobicContact CG-CD2 4.15Å; C35-L40 HydrophobicContact CB-CD1 4.18Å; C35-L40 HydrophobicContact CB-CD2 3.79Å; C35-L40 HydrophobicContact CB-CG 3.81Å; P36-L40 PolarHBondContact O-N 3.34Å; S37-L40 PolarHBondContact O-N 3.19Å; L40-W42 PolarHBondContact O-N 3Å; L40-R45 VanDerWaalsContact O-CD 3.31Å; L40-R45 WeakPolarHBondContact O-CD 3.37Å; L40-R45 PolarHBondContact O-NE 3.49Å; L40-P345 HydrophobicContact CD2-CB 4.25Å; L40-P345 HydrophobicContact CD2-CG 3.97Å
41N98Very high97.3Very high81 Ų8152.7 Ų52.743%0.43327%0.271SS..SBendtrans-53.2129.4-177.7-174.6-78.2000111.8S37 E43 Y44 R45S37-N41 PolarHBondContact O-N 2.76Å; N41-E43 VanDerWaalsContact C-N 3.26Å; N41-E43 PolarHBondContact O-N 2.96Å; N41-E43 VanDerWaalsContact OD1-CB 3.23Å; N41-E43 WeakPolarHBondContact OD1-CB 3.24Å; N41-E43 PolarHBondContact OD1-N 2.97Å; N41-Y44 WeakPolarHBondContact O-CB 3.34Å; N41-Y44 PolarHBondContact O-N 3.23Å; N41-R45 PolarHBondContact O-N 3.47Å
42W98.1Very high97.4Very high13 Ų1349.5 Ų49.55%0.04926%0.256CS..Hα-helixtrans-53-39.3-179.3-178.8-112.9000114.2D24 L40 Y44 R45 K46 I49 Q70 L74 F75D24-W42 HydrophobicContact CB-CB 4.04Å; D24-W42 HydrophobicContact CB-CD2 4.4Å; D24-W42 HydrophobicContact CB-CE3 4.3Å; D24-W42 HydrophobicContact CB-CG 4.32Å; D24-W42 WeakPolarHBondContact OD1-CB 3.4Å; L40-W42 PolarHBondContact O-N 3Å; W42-Y44 PolarHBondContact O-N 2.9Å; W42-R45 PolarHBondContact O-N 2.67Å; W42-K46 HydrophobicContact CD2-CB 4.1Å; W42-K46 HydrophobicContact CH2-CB 4.35Å; W42-K46 HydrophobicContact CZ2-CB 3.84Å; W42-K46 VanDerWaalsContact O-CB 3.23Å; W42-K46 WeakPolarHBondContact O-CB 3.4Å; W42-K46 VanDerWaalsContact O-CG 3.26Å; W42-K46 WeakPolarHBondContact O-CG 3.18Å; W42-K46 PolarHBondContact O-N 3.42Å; W42-I49 HydrophobicContact CH2-CD1 4.19Å; W42-I49 HydrophobicContact CZ3-CD1 3.86Å; W42-Q70 HydrophobicContact CZ2-CB 3.91Å; W42-Q70 HydrophobicContact CZ2-CG 3.59Å; W42-L74 HydrophobicContact CZ2-CD2 3.8Å; W42-F75 HydrophobicContact CH2-CE2 4.15Å; W42-F75 HydrophobicContact CH2-CZ 4.13Å; W42-F75 HydrophobicContact CZ2-CE2 4.3Å
43E97.8Very high97.4Very high121 Ų12149.5 Ų49.557%0.56526%0.256SS*.Hα-helixtrans-62.1-29.5-179.1-62.8-61.3111.300112.3N41 K46N41-E43 VanDerWaalsContact C-N 3.26Å; N41-E43 PolarHBondContact O-N 2.96Å; N41-E43 VanDerWaalsContact OD1-CB 3.23Å; N41-E43 WeakPolarHBondContact OD1-CB 3.24Å; N41-E43 PolarHBondContact OD1-N 2.97Å; E43-K46 IonicContact OE1-NZ 2.57Å; E43-K46 PolarHBondContact OE1-NZ 2.74Å; E43-K46 VanDerWaalsContact OE2-CE 3.31Å; E43-K46 WeakPolarHBondContact OE2-CE 3.3Å; E43-K46 IonicContact OE2-NZ 2.72Å; E43-K46 PolarHBondContact OE2-NZ 2.99Å
44Y97.9Very high97.5Very high82 Ų8250.6 Ų50.632%0.32225%0.247SC..Hα-helixtrans-80.4-53.4172.3-177-97.2000111.6W38 A39 N41 W42 K46 G47 L48 P347W38-Y44 HydrophobicContact CE3-CD2 4.28Å; W38-Y44 HydrophobicContact CE3-CE1 4.47Å; W38-Y44 HydrophobicContact CE3-CE2 4.24Å; W38-Y44 HydrophobicContact CE3-CG 4.42Å; W38-Y44 HydrophobicContact CZ3-CD1 4.41Å; W38-Y44 HydrophobicContact CZ3-CD2 4.24Å; W38-Y44 AromaticContact CZ3-CE1 3.93Å; W38-Y44 HydrophobicContact CZ3-CE1 3.93Å; W38-Y44 AromaticContact CZ3-CE2 3.74Å; W38-Y44 HydrophobicContact CZ3-CE2 3.74Å; W38-Y44 AromaticContact CZ3-CZ 3.58Å; W38-Y44 VanDerWaalsContact O-CB 3.31Å; W38-Y44 WeakPolarHBondContact O-CB 3.48Å; A39-Y44 HydrophobicContact CB-CD1 4.37Å; A39-Y44 HydrophobicContact CB-CE1 4.33Å; N41-Y44 WeakPolarHBondContact O-CB 3.34Å; N41-Y44 PolarHBondContact O-N 3.23Å; W42-Y44 PolarHBondContact O-N 2.9Å; Y44-K46 PolarHBondContact O-N 2.82Å; Y44-G47 PolarHBondContact O-N 2.84Å; Y44-L48 HydrophobicContact CD1-CD1 4.22Å; Y44-L48 HydrophobicContact CE1-CD1 3.52Å; Y44-L48 HydrophobicContact CE1-CG 4.39Å; Y44-P347 PolarHBondContact OH-O 2.79Å
45R98.3Very high97.5Very high0 Ų052.9 Ų52.90%027%0.267CS..Hα-helixtrans-61.4-41.3-174.3-65.4-166.9-53.3109.5-4.1112.6V21 L22 A39 L40 N41 W42 G47 L48 I49 A350V21-R45 PolarHBondContact O-NH1 3.37Å; L22-R45 VanDerWaalsContact O-CZ 3.31Å; L22-R45 PolarHBondContact O-NH1 3Å; L22-R45 PolarHBondContact O-NH2 2.98Å; A39-R45 WeakPolarHBondContact O-CD 3.11Å; A39-R45 WeakPolarHBondContact O-CG 3.29Å; L40-R45 VanDerWaalsContact O-CD 3.31Å; L40-R45 WeakPolarHBondContact O-CD 3.37Å; L40-R45 PolarHBondContact O-NE 3.49Å; N41-R45 PolarHBondContact O-N 3.47Å; W42-R45 PolarHBondContact O-N 2.67Å; R45-G47 PolarHBondContact O-N 2.84Å; R45-L48 WeakPolarHBondContact O-CB 3.46Å; R45-L48 PolarHBondContact O-N 2.75Å; R45-I49 HydrophobicContact CB-CD1 4.26Å; R45-I49 WeakPolarHBondContact O-CG1 3.44Å; R45-I49 PolarHBondContact O-N 2.7Å; R45-A350 HydrophobicContact CB-CB 4.29Å; R45-A350 VanDerWaalsContact CD-O 3.29Å; R45-A350 WeakPolarHBondContact CD-O 3.29Å; R45-A350 PolarHBondContact NH1-O 2.06Å
46K97.9Very high97.5Very high47 Ų4755.5 Ų55.520%0.20428%0.276CS..Hα-helixtrans-58-35.8-176.778-174.5-176.8-175.30112.8W42 E43 Y44 I49 I50 L74W42-K46 HydrophobicContact CD2-CB 4.1Å; W42-K46 HydrophobicContact CH2-CB 4.35Å; W42-K46 HydrophobicContact CZ2-CB 3.84Å; W42-K46 VanDerWaalsContact O-CB 3.23Å; W42-K46 WeakPolarHBondContact O-CB 3.4Å; W42-K46 VanDerWaalsContact O-CG 3.26Å; W42-K46 WeakPolarHBondContact O-CG 3.18Å; W42-K46 PolarHBondContact O-N 3.42Å; E43-K46 IonicContact OE1-NZ 2.57Å; E43-K46 PolarHBondContact OE1-NZ 2.74Å; E43-K46 VanDerWaalsContact OE2-CE 3.31Å; E43-K46 WeakPolarHBondContact OE2-CE 3.3Å; E43-K46 IonicContact OE2-NZ 2.72Å; E43-K46 PolarHBondContact OE2-NZ 2.99Å; Y44-K46 PolarHBondContact O-N 2.82Å; K46-I49 PolarHBondContact O-N 3.07Å; K46-I50 WeakPolarHBondContact O-CB 3.06Å; K46-I50 WeakPolarHBondContact O-CG1 3.34Å; K46-I50 PolarHBondContact O-N 2.79Å; K46-L74 HydrophobicContact CB-CD2 3.74Å; K46-L74 HydrophobicContact CD-CD1 4.45Å; K46-L74 HydrophobicContact CD-CD2 4.38Å; K46-L74 HydrophobicContact CG-CD2 4.41Å
47G97.4Very high97.4Very high44 Ų4459.6 Ų59.645%0.45429%0.291SS..Hα-helixtrans-65.6-40176.500000112.4Y44 R45 K51Y44-G47 PolarHBondContact O-N 2.84Å; R45-G47 PolarHBondContact O-N 2.84Å; G47-K51 VanDerWaalsContact O-CB 3.3Å; G47-K51 WeakPolarHBondContact O-CB 3.35Å; G47-K51 PolarHBondContact O-N 3.46Å
48L98Very high97.5Very high44 Ų4456 Ų5623%0.2327%0.265CS..Hα-helixtrans-70.8-43.2175.9-65.9-178.5000112Y44 R45 I50 K51 E52 A350Y44-L48 HydrophobicContact CD1-CD1 4.22Å; Y44-L48 HydrophobicContact CE1-CD1 3.52Å; Y44-L48 HydrophobicContact CE1-CG 4.39Å; R45-L48 WeakPolarHBondContact O-CB 3.46Å; R45-L48 PolarHBondContact O-N 2.75Å; L48-I50 PolarHBondContact O-N 2.74Å; L48-K51 WeakPolarHBondContact O-CB 3.34Å; L48-K51 PolarHBondContact O-N 3.45Å; L48-E52 WeakPolarHBondContact O-CB 3.26Å; L48-E52 PolarHBondContact O-N 2.57Å; L48-A350 HydrophobicContact CB-CB 3.57Å; L48-A350 HydrophobicContact CD1-CB 4.19Å
49I98.5Very high97.6Very high0 Ų049.7 Ų49.70%024%0.243CC..Hα-helixtrans-57.9-48.9176.9-67.3161.9000110.4Y19 V21 W42 R45 K46 K51 E52 I53 F75 A350Y19-I49 HydrophobicContact CE1-CG2 4.31Å; V21-I49 HydrophobicContact CB-CD1 4.23Å; V21-I49 HydrophobicContact CB-CG2 4.2Å; V21-I49 HydrophobicContact CG1-CG2 3.92Å; W42-I49 HydrophobicContact CH2-CD1 4.19Å; W42-I49 HydrophobicContact CZ3-CD1 3.86Å; R45-I49 HydrophobicContact CB-CD1 4.26Å; R45-I49 WeakPolarHBondContact O-CG1 3.44Å; R45-I49 PolarHBondContact O-N 2.7Å; K46-I49 PolarHBondContact O-N 3.07Å; I49-K51 VanDerWaalsContact C-N 3.35Å; I49-K51 PolarHBondContact O-N 3.34Å; I49-E52 PolarHBondContact O-N 3.49Å; I49-I53 HydrophobicContact CG2-CD1 3.89Å; I49-I53 WeakPolarHBondContact O-CG1 3.44Å; I49-I53 PolarHBondContact O-N 2.62Å; I49-F75 HydrophobicContact CG2-CE1 3.88Å; I49-F75 HydrophobicContact CG2-CZ 4.21Å; I49-A350 HydrophobicContact CD1-CB 4.42Å; I49-A350 HydrophobicContact CG1-CB 3.67Å
50I98.3Very high97.6Very high10 Ų1049.7 Ų49.75%0.05124%0.242CC..Hα-helixtrans-64.9-39.4178.1-68.1-63.1000111.4K46 L48 E52 R54 L74 F75 E78K46-I50 WeakPolarHBondContact O-CB 3.06Å; K46-I50 WeakPolarHBondContact O-CG1 3.34Å; K46-I50 PolarHBondContact O-N 2.79Å; L48-I50 PolarHBondContact O-N 2.74Å; I50-E52 VanDerWaalsContact C-N 3.33Å; I50-E52 PolarHBondContact O-N 2.86Å; I50-R54 HydrophobicContact CG2-CG 4.37Å; I50-R54 VanDerWaalsContact CG2-NE 3.33Å; I50-R54 VanDerWaalsContact O-CB 3.3Å; I50-R54 WeakPolarHBondContact O-CB 3.31Å; I50-R54 WeakPolarHBondContact O-CD 3.5Å; I50-R54 WeakPolarHBondContact O-CG 3.19Å; I50-R54 PolarHBondContact O-N 3.02Å; I50-L74 HydrophobicContact CD1-CD2 4.38Å; I50-L74 HydrophobicContact CD1-CG 4.15Å; I50-L74 HydrophobicContact CG1-CD1 4.05Å; I50-L74 HydrophobicContact CG1-CD2 4.17Å; I50-L74 HydrophobicContact CG1-CG 4.1Å; I50-F75 HydrophobicContact CD1-CD1 3.92Å; I50-F75 HydrophobicContact CD1-CE1 4.2Å; I50-E78 HydrophobicContact CD1-CB 4.16Å; I50-E78 HydrophobicContact CD1-CG 4.43Å; I50-E78 HydrophobicContact CG2-CB 4.41Å; I50-E78 HydrophobicContact CG2-CG 4.49Å
51K97.7Very high97.7Very high136 Ų13649.4 Ų49.459%0.59124%0.241SC*.Hα-helixtrans-61.2-42.4175.5-178.7-176176.6-173.70111.7G47 L48 I49 R54 T55G47-K51 VanDerWaalsContact O-CB 3.3Å; G47-K51 WeakPolarHBondContact O-CB 3.35Å; G47-K51 PolarHBondContact O-N 3.46Å; L48-K51 WeakPolarHBondContact O-CB 3.34Å; L48-K51 PolarHBondContact O-N 3.45Å; I49-K51 VanDerWaalsContact C-N 3.35Å; I49-K51 PolarHBondContact O-N 3.34Å; K51-R54 WeakPolarHBondContact O-CB 3.24Å; K51-R54 PolarHBondContact O-N 2.92Å; K51-T55 WeakPolarHBondContact O-CB 3.42Å; K51-T55 PolarHBondContact O-N 3.08Å; K51-T55 PolarHBondContact O-OG1 2.99Å
52E95.8Very high97.8Very high38 Ų3845.6 Ų45.618%0.17822%0.22CC..Hα-helixtrans-64.9-50.4179-179164.1-127.200111.1Y19 L48 I49 I50 R54 T55 Y56 P355Y19-E52 VanDerWaalsContact CE1-OE2 3.24Å; Y19-E52 WeakPolarHBondContact CE1-OE2 3.44Å; Y19-E52 PolarHBondContact OH-OE2 2.56Å; L48-E52 WeakPolarHBondContact O-CB 3.26Å; L48-E52 PolarHBondContact O-N 2.57Å; I49-E52 PolarHBondContact O-N 3.49Å; I50-E52 VanDerWaalsContact C-N 3.33Å; I50-E52 PolarHBondContact O-N 2.86Å; E52-R54 VanDerWaalsContact C-N 3.29Å; E52-R54 PolarHBondContact O-N 2.92Å; E52-T55 WeakPolarHBondContact O-CB 3.3Å; E52-T55 PolarHBondContact O-N 2.95Å; E52-Y56 HydrophobicContact CG-CD2 4.05Å; E52-Y56 HydrophobicContact CG-CE2 3.37Å; E52-Y56 WeakPolarHBondContact O-CD2 3.13Å; E52-Y56 PolarHBondContact O-N 3.26Å; E52-P355 HydrophobicContact CG-CG 4.19Å; E52-P355 WeakPolarHBondContact OE1-CG 3.33Å
53I97.5Very high97.8Very high2 Ų245 Ų451%0.0122%0.218CC..Hα-helixtrans-56.5-43.4175.1-67.7168.7000111.4L17 I49 T55 Y56 E57 I61 L63 F75 L79L17-I53 HydrophobicContact CD2-CG1 4.42Å; I49-I53 HydrophobicContact CG2-CD1 3.89Å; I49-I53 WeakPolarHBondContact O-CG1 3.44Å; I49-I53 PolarHBondContact O-N 2.62Å; I53-T55 VanDerWaalsContact C-N 3.31Å; I53-T55 PolarHBondContact O-N 3.4Å; I53-Y56 PolarHBondContact O-N 2.86Å; I53-E57 PolarHBondContact O-N 3.41Å; I53-I61 HydrophobicContact CG2-CD1 3.68Å; I53-L63 HydrophobicContact CD1-CD1 4.03Å; I53-L63 HydrophobicContact CD1-CD2 4.24Å; I53-F75 HydrophobicContact CD1-CD1 4.33Å; I53-F75 HydrophobicContact CD1-CE1 4.06Å; I53-L79 HydrophobicContact CG2-CD2 3.63Å
54R97.1Very high97.8Very high109 Ų10939.2 Ų39.241%0.41119%0.191SC..Hα-helixtrans-61.5-36.9175.7-80.1167.6178.6-163.43113I50 K51 E52 E57 E78 L82I50-R54 HydrophobicContact CG2-CG 4.37Å; I50-R54 VanDerWaalsContact CG2-NE 3.33Å; I50-R54 VanDerWaalsContact O-CB 3.3Å; I50-R54 WeakPolarHBondContact O-CB 3.31Å; I50-R54 WeakPolarHBondContact O-CD 3.5Å; I50-R54 WeakPolarHBondContact O-CG 3.19Å; I50-R54 PolarHBondContact O-N 3.02Å; K51-R54 WeakPolarHBondContact O-CB 3.24Å; K51-R54 PolarHBondContact O-N 2.92Å; E52-R54 VanDerWaalsContact C-N 3.29Å; E52-R54 PolarHBondContact O-N 2.92Å; R54-E57 WeakPolarHBondContact O-CG 3.42Å; R54-E78 IonicContact CZ-OE2 3.59Å; R54-E78 IonicContact NH2-OE2 2.7Å; R54-E78 PolarHBondContact NH2-OE2 3.11Å; R54-L82 HydrophobicContact CG-CD1 3.42Å; R54-L82 VanDerWaalsContact CG-CD1 3.42Å; R54-L82 HydrophobicContact CG-CD2 4.44Å
55T96.7Very high97.9Very high98 Ų9836 Ų3660%0.60118%0.179SC*.Hα-helixtrans-70.9-34.7-176.2-590000111.5K51 E52 I53K51-T55 WeakPolarHBondContact O-CB 3.42Å; K51-T55 PolarHBondContact O-N 3.08Å; K51-T55 PolarHBondContact O-OG1 2.99Å; E52-T55 WeakPolarHBondContact O-CB 3.3Å; E52-T55 PolarHBondContact O-N 2.95Å; I53-T55 VanDerWaalsContact C-N 3.31Å; I53-T55 PolarHBondContact O-N 3.4Å
56Y96.3Very high97.9Very high61 Ų6136 Ų3624%0.23918%0.179CC..Hα-helixtrans-76-25.3-179.9-68.2-54.3000114.2L17 E52 I53 A58 L328 P355 M357L17-Y56 HydrophobicContact CD1-CD2 3.73Å; L17-Y56 HydrophobicContact CD1-CE2 4.21Å; L17-Y56 HydrophobicContact CD1-CG 4.12Å; L17-Y56 HydrophobicContact CD2-CD2 4.04Å; E52-Y56 HydrophobicContact CG-CD2 4.05Å; E52-Y56 HydrophobicContact CG-CE2 3.37Å; E52-Y56 WeakPolarHBondContact O-CD2 3.13Å; E52-Y56 PolarHBondContact O-N 3.26Å; I53-Y56 PolarHBondContact O-N 2.86Å; Y56-A58 PolarHBondContact O-N 2.95Å; Y56-L328 HydrophobicContact CD1-CD2 4.08Å; Y56-L328 HydrophobicContact CE1-CD1 4.16Å; Y56-L328 HydrophobicContact CE1-CD2 3.33Å; Y56-L328 HydrophobicContact CE1-CG 4.4Å; Y56-P355 HydrophobicContact CE2-CB 3.88Å; Y56-P355 HydrophobicContact CE2-CG 3.5Å; Y56-P355 WeakPolarHBondContact OH-CG 3.2Å; Y56-M357 HydrophobicContact CD1-SD 4.05Å; Y56-M357 HydrophobicContact CG-SD 4.21Å; Y56-M357 WeakPolarHBondContact O-CE 3.19Å
57E96.1Very high97.9Very high138 Ų13834.1 Ų34.165%0.64517%0.171SC*.  trans48.434.9-179.7-59.3-167.310300113.8I53 R54I53-E57 PolarHBondContact O-N 3.41Å; R54-E57 WeakPolarHBondContact O-CG 3.42Å
58A98.3Very high98Very high0 Ų032.3 Ų32.30%015%0.151CC..  trans-64.7144-17500000112T15 L17 Y56 I61 Y84 M357T15-A58 VanDerWaalsContact OG1-CA 3.28Å; T15-A58 WeakPolarHBondContact OG1-CA 3.1Å; L17-A58 HydrophobicContact CB-CB 3.53Å; Y56-A58 PolarHBondContact O-N 2.95Å; A58-I61 HydrophobicContact CB-CG1 4.05Å; A58-Y84 WeakPolarHBondContact O-CE1 3.28Å; A58-Y84 PolarHBondContact O-OH 2.85Å; A58-M357 HydrophobicContact CB-CE 3.86Å
59D98.7Very high97.9Very high14 Ų1432.9 Ų32.98%0.07515%0.153CC..SBendtrans-74.2-31.5-178.3-63.5-52.3000113.1F14 T15 W112 K113 K116 F117F14-D59 WeakPolarHBondContact CA-OD2 3.11Å; F14-D59 HydrophobicContact CB-CB 3.99Å; F14-D59 WeakPolarHBondContact CB-OD2 3.45Å; T15-D59 PolarHBondContact N-OD2 2.92Å; T15-D59 WeakPolarHBondContact O-CB 3.47Å; T15-D59 PolarHBondContact O-N 2.93Å; T15-D59 VanDerWaalsContact O-N 3.11Å; T15-D59 PolarHBondContact OG1-N 2.86Å; T15-D59 PolarHBondContact OG1-OD2 2.85Å; D59-W112 CarbonylContact O-C 3.46Å; D59-W112 VanDerWaalsContact O-CA 3.29Å; D59-W112 WeakPolarHBondContact O-CA 3.45Å; D59-K113 PolarHBondContact O-N 3.18Å; D59-K116 HydrophobicContact CB-CD 4.14Å; D59-K116 VanDerWaalsContact OD1-CD 3.25Å; D59-K116 WeakPolarHBondContact OD1-CD 3.33Å; D59-K116 VanDerWaalsContact OD1-CE 3.28Å; D59-K116 WeakPolarHBondContact OD1-CE 3.29Å; D59-K116 IonicContact OD1-NZ 2.71Å; D59-K116 PolarHBondContact OD1-NZ 3.26Å; D59-K116 IonicContact OD2-NZ 2.79Å; D59-K116 PolarHBondContact OD2-NZ 3.23Å; D59-F117 HydrophobicContact CB-CE2 4.1Å
60V98.9Very high97.9Very high0 Ų034 Ų340%016%0.158CC..EExtended strand (participates in β ladder)trans-126.5134.3172.6177.90000108.3F14 T15 V16 L17 I110 F111 W112 F117 L157 V187F14-V60 HydrophobicContact CD2-CG2 4.22Å; F14-V60 HydrophobicContact CE2-CG2 4.44Å; T15-V60 PolarHBondContact O-N 2.94Å; V16-V60 CarbonylContact C-O 3.53Å; V16-V60 VanDerWaalsContact CA-O 3.27Å; V16-V60 WeakPolarHBondContact CA-O 3.24Å; V16-V60 HydrophobicContact CB-CB 4.42Å; V16-V60 HydrophobicContact CG2-CB 4.3Å; V16-V60 HydrophobicContact CG2-CG1 4.23Å; L17-V60 PolarHBondContact N-O 2.89Å; V60-I110 HydrophobicContact CG1-CG2 4.48Å; V60-F111 CarbonylContact C-O 3.54Å; V60-F111 WeakPolarHBondContact CA-O 3.48Å; V60-W112 HydrophobicContact CG2-CB 4.49Å; V60-F117 HydrophobicContact CG2-CD2 4.34Å; V60-F117 HydrophobicContact CG2-CE2 3.91Å; V60-F117 HydrophobicContact CG2-CZ 4.37Å; V60-L157 HydrophobicContact CG2-CD1 4.29Å; V60-V187 HydrophobicContact CG1-CG1 3.84Å; V60-V187 HydrophobicContact CG1-CG2 4.25Å
61I98.9Very high97.9Very high0 Ų034.3 Ų34.30%016%0.159CC..EExtended strand (participates in β ladder)trans-126.3126.3178.6-57.7158.6000108.3L17 I53 A58 L63 L79 Y84 I110 F111L17-I61 HydrophobicContact CB-CG1 4.26Å; L17-I61 HydrophobicContact CB-CG2 4.44Å; L17-I61 HydrophobicContact CD2-CG1 4.28Å; L17-I61 HydrophobicContact CD2-CG2 4.05Å; L17-I61 CarbonylContact O-C 3.48Å; L17-I61 WeakPolarHBondContact O-CA 3.32Å; I53-I61 HydrophobicContact CG2-CD1 3.68Å; A58-I61 HydrophobicContact CB-CG1 4.05Å; I61-L63 HydrophobicContact CG2-CD1 4.47Å; I61-L63 HydrophobicContact CG2-CD2 3.53Å; I61-L63 HydrophobicContact CG2-CG 3.82Å; I61-L79 HydrophobicContact CD1-CD2 4.33Å; I61-Y84 HydrophobicContact CD1-CD1 4.09Å; I61-Y84 HydrophobicContact CD1-CE1 3.53Å; I61-Y84 HydrophobicContact CD1-CE2 4.45Å; I61-Y84 HydrophobicContact CG1-CE1 4.21Å; I61-I110 CarbonylContact O-C 3.57Å; I61-I110 WeakPolarHBondContact O-CA 3.29Å; I61-F111 HydrophobicContact CB-CB 4.22Å; I61-F111 PolarHBondContact N-O 2.84Å; I61-F111 PolarHBondContact O-N 2.97Å
62T98.9Very high98Very high0 Ų035.4 Ų35.40%016%0.159CC..EExtended strand (participates in β ladder)trans-113.8120.317264.20000109.6L17 C18 Y19 A109 I110 V187 C236L17-T62 PolarHBondContact O-N 3.34Å; L17-T62 PolarHBondContact O-OG1 3.05Å; C18-T62 WeakPolarHBondContact CA-O 3.39Å; C18-T62 WeakPolarHBondContact CA-OG1 3.43Å; Y19-T62 PolarHBondContact N-O 2.89Å; T62-A109 CarbonylContact C-O 3.5Å; T62-A109 WeakPolarHBondContact CA-O 3.37Å; T62-I110 HydrophobicContact CG2-CG1 4.36Å; T62-V187 HydrophobicContact CG2-CG1 3.94Å; T62-C236 HydrophobicContact CG2-CB 3.96Å; T62-C236 WeakPolarHBondContact OG1-CB 3.13Å
63L98.9Very high98.1Very high0 Ų037.7 Ų37.70%018%0.176CC..EExtended strand (participates in β ladder)trans-113.9142.6-179.1-55.1-178.6000111.3Y19 V21 I53 I61 V66 F75 C108 A109 F111Y19-L63 HydrophobicContact CD1-CD2 4.41Å; Y19-L63 VanDerWaalsContact O-CA 3.26Å; Y19-L63 WeakPolarHBondContact O-CA 3.48Å; V21-L63 HydrophobicContact CG1-CD1 4.36Å; V21-L63 HydrophobicContact CG1-CD2 4.03Å; I53-L63 HydrophobicContact CD1-CD1 4.03Å; I53-L63 HydrophobicContact CD1-CD2 4.24Å; I61-L63 HydrophobicContact CG2-CD1 4.47Å; I61-L63 HydrophobicContact CG2-CD2 3.53Å; I61-L63 HydrophobicContact CG2-CG 3.82Å; L63-V66 HydrophobicContact CB-CG2 3.46Å; L63-V66 VanDerWaalsContact CB-CG2 3.46Å; L63-V66 HydrophobicContact CD1-CG2 3.99Å; L63-V66 HydrophobicContact CG-CG2 4.38Å; L63-F75 HydrophobicContact CD1-CD1 3.79Å; L63-F75 HydrophobicContact CD1-CE1 3.82Å; L63-C108 CarbonylContact O-C 3.58Å; L63-C108 VanDerWaalsContact O-CA 3.28Å; L63-C108 WeakPolarHBondContact O-CA 3.31Å; L63-A109 HydrophobicContact CB-CB 4.39Å; L63-A109 PolarHBondContact N-O 2.91Å; L63-A109 PolarHBondContact O-N 2.87Å; L63-F111 HydrophobicContact CD1-CD2 4.43Å; L63-F111 HydrophobicContact CD1-CE2 3.98Å
64Q98.8Very high98.1Very high0 Ų038.5 Ų38.50%018%0.18CC..EExtended strand (participates in β ladder)trans-114158.9168.6-56.174.748.800109.2Y19 N20 V21 V66 T189 H191 D238Y19-Q64 VanDerWaalsContact C-OE1 3.27Å; Y19-Q64 PolarHBondContact O-N 3.42Å; Y19-Q64 VanDerWaalsContact O-N 3.12Å; Y19-Q64 PolarHBondContact O-OE1 2.82Å; N20-Q64 HydrophobicContact CB-CB 4.08Å; V21-Q64 WeakPolarHBondContact CG2-O 3.28Å; V21-Q64 PolarHBondContact N-O 3.46Å; V21-Q64 VanDerWaalsContact N-O 3.1Å; Q64-V66 VanDerWaalsContact C-N 3.27Å; Q64-V66 PolarHBondContact O-N 2.84Å; Q64-T189 PolarHBondContact NE2-OG1 2.99Å; Q64-H191 HydrophobicContact CB-CB 4.24Å; Q64-H191 HydrophobicContact CG-CB 4.08Å; Q64-D238 HydrophobicContact CG-CB 4.29Å
65E98.6Very high98.2Very high15 Ų1533.3 Ų33.37%0.0716%0.16CC..EExtended strand (participates in β ladder)trans59.733.3-177-60.7-164.5-157.700114.8N20 V21 L22 C23 Y26 G107 H191N20-E65 PolarHBondContact ND2-OE1 2.89Å; N20-E65 VanDerWaalsContact OD1-CB 3.3Å; N20-E65 WeakPolarHBondContact OD1-CB 3.33Å; N20-E65 WeakPolarHBondContact OD1-CG 3.29Å; N20-E65 PolarHBondContact OD1-OE1 3.37Å; V21-E65 WeakPolarHBondContact CG2-O 3.46Å; L22-E65 WeakPolarHBondContact CA-OE2 3.37Å; C23-E65 HydrophobicContact CB-CB 4.05Å; C23-E65 WeakPolarHBondContact CB-O 3.2Å; C23-E65 PolarHBondContact N-OE2 3.25Å; C23-E65 PolarHBondContact SG-OE2 3.22Å; C23-E65 VanDerWaalsContact SG-OE2 3.39Å; Y26-E65 WeakPolarHBondContact CD2-OE2 3.29Å; E65-G107 PolarHBondContact N-O 3.41Å; E65-H191 IonicContact OE1-CE1 2.92Å; E65-H191 PolarHBondContact OE1-CE1 3.33Å
66V98.7Very high98.3Very high0 Ų032.6 Ų32.60%015%0.151CC..EExtended strand (participates in β ladder)trans-82.2119.6171.6179.60000108.9V21 L63 Q64 F71 F75 F88 D106 G107 A109V21-V66 HydrophobicContact CG2-CG2 4.26Å; L63-V66 HydrophobicContact CB-CG2 3.46Å; L63-V66 VanDerWaalsContact CB-CG2 3.46Å; L63-V66 HydrophobicContact CD1-CG2 3.99Å; L63-V66 HydrophobicContact CG-CG2 4.38Å; Q64-V66 VanDerWaalsContact C-N 3.27Å; Q64-V66 PolarHBondContact O-N 2.84Å; V66-F71 HydrophobicContact CG1-CB 3.82Å; V66-F71 HydrophobicContact CG1-CD2 4.38Å; V66-F75 HydrophobicContact CG1-CD2 3.69Å; V66-F75 HydrophobicContact CG1-CE2 3.86Å; V66-F75 HydrophobicContact CG1-CG 4.47Å; V66-F75 HydrophobicContact CG2-CE2 4.45Å; V66-F88 HydrophobicContact CB-CD2 4.24Å; V66-F88 HydrophobicContact CB-CE2 4.05Å; V66-F88 HydrophobicContact CG1-CD2 4.18Å; V66-F88 HydrophobicContact CG1-CE2 4.17Å; V66-F88 WeakPolarHBondContact O-CE2 3.36Å; V66-F88 WeakPolarHBondContact O-CZ 3.42Å; V66-D106 CarbonylContact O-C 3.47Å; V66-D106 VanDerWaalsContact O-CA 3.25Å; V66-D106 WeakPolarHBondContact O-CA 3.25Å; V66-G107 PolarHBondContact N-O 3.02Å; V66-G107 VanDerWaalsContact N-O 3.14Å; V66-G107 PolarHBondContact O-N 2.87Å; V66-A109 HydrophobicContact CG2-CB 4.18Å
67E98.4Very high98.4Very high7 Ų732 Ų323%0.03315%0.154CC..EExtended strand (participates in β ladder)trans-70.9145173.7-66.8-172.8-172.400112.2C23 D24 K25 E69 Q70 F71C23-E67 HydrophobicContact CB-CG 3.75Å; D24-E67 WeakPolarHBondContact CB-OE1 3.34Å; D24-E67 PolarHBondContact N-OE1 3.01Å; K25-E67 PolarHBondContact N-OE1 2.73Å; E67-E69 VanDerWaalsContact C-N 3.35Å; E67-E69 PolarHBondContact O-N 2.74Å; E67-Q70 HydrophobicContact CB-CB 4.17Å; E67-Q70 HydrophobicContact CB-CG 3.92Å; E67-Q70 PolarHBondContact O-N 3.31Å; E67-Q70 VanDerWaalsContact O-N 3.11Å; E67-F71 PolarHBondContact O-N 3.17Å
68T98.1Very high98.5Very high6 Ų627.9 Ų27.94%0.03714%0.135CC..Hα-helixtrans-56-44.5-174.8-64.10000113.2F88 A90 R102 K103 V105T68-F88 HydrophobicContact CG2-CE1 4.12Å; T68-F88 WeakPolarHBondContact OG1-CE1 3.09Å; T68-A90 WeakPolarHBondContact OG1-CB 3.42Å; T68-R102 WeakPolarHBondContact CB-O 3.23Å; T68-R102 PolarHBondContact OG1-O 2.99Å; T68-K103 WeakPolarHBondContact CB-O 3.41Å; T68-K103 PolarHBondContact N-O 3.35Å; T68-V105 PolarHBondContact N-O 2.82Å; T68-V105 PolarHBondContact OG1-O 2.82Å
69E97.5Very high98.5Very high57 Ų5727.9 Ų27.927%0.26614%0.135SC..Hα-helixtrans-69.5-43.1176.9-178.3167-12000111.4E67 F71 R72 T73 K103E67-E69 VanDerWaalsContact C-N 3.35Å; E67-E69 PolarHBondContact O-N 2.74Å; E69-F71 VanDerWaalsContact C-N 3.29Å; E69-F71 PolarHBondContact O-N 2.88Å; E69-R72 PolarHBondContact O-N 2.9Å; E69-T73 HydrophobicContact CG-CG2 3.95Å; E69-T73 PolarHBondContact O-N 3.35Å; E69-T73 PolarHBondContact O-OG1 3.08Å; E69-K103 HydrophobicContact CB-CB 3.94Å; E69-K103 HydrophobicContact CB-CG 4.44Å; E69-K103 PolarHBondContact N-O 3.17Å
70Q98.4Very high98.5Very high23 Ų2334.6 Ų34.611%0.10716%0.163CC..Hα-helixtrans-64.6-32.9-179.6-59.3-55.9-37.100112.4W42 E67 R72 L74 F75W42-Q70 HydrophobicContact CZ2-CB 3.91Å; W42-Q70 HydrophobicContact CZ2-CG 3.59Å; E67-Q70 HydrophobicContact CB-CB 4.17Å; E67-Q70 HydrophobicContact CB-CG 3.92Å; E67-Q70 PolarHBondContact O-N 3.31Å; E67-Q70 VanDerWaalsContact O-N 3.11Å; Q70-R72 VanDerWaalsContact C-N 3.29Å; Q70-R72 PolarHBondContact O-N 2.8Å; Q70-L74 CarbonylContact O-C 3.57Å; Q70-L74 WeakPolarHBondContact O-CA 3.23Å; Q70-L74 VanDerWaalsContact O-CB 3.29Å; Q70-L74 WeakPolarHBondContact O-CB 3.28Å; Q70-L74 PolarHBondContact O-N 2.8Å; Q70-F75 HydrophobicContact CB-CD2 4.22Å; Q70-F75 HydrophobicContact CB-CE2 4.07Å; Q70-F75 WeakPolarHBondContact O-CD2 3.28Å; Q70-F75 PolarHBondContact O-N 3.17Å
71F98.6Very high98.5Very high16 Ų1641.6 Ų41.67%0.0720%0.196CC..Iπ-helixtrans-56-47.2170.1178.6-98.2000111.1V66 E67 E69 Q76 F88 A109 F111V66-F71 HydrophobicContact CG1-CB 3.82Å; V66-F71 HydrophobicContact CG1-CD2 4.38Å; E67-F71 PolarHBondContact O-N 3.17Å; E69-F71 VanDerWaalsContact C-N 3.29Å; E69-F71 PolarHBondContact O-N 2.88Å; F71-Q76 HydrophobicContact CE1-CB 4.26Å; F71-Q76 HydrophobicContact CZ-CB 4.32Å; F71-Q76 WeakPolarHBondContact O-CB 3.43Å; F71-Q76 PolarHBondContact O-N 3.31Å; F71-F88 HydrophobicContact CB-CB 4.31Å; F71-F88 HydrophobicContact CB-CD1 4.23Å; F71-F88 HydrophobicContact CB-CD2 4.27Å; F71-F88 HydrophobicContact CB-CG 4Å; F71-F88 HydrophobicContact CD1-CB 3.64Å; F71-F88 HydrophobicContact CD1-CD1 4.26Å; F71-F88 HydrophobicContact CD1-CG 4.09Å; F71-F88 HydrophobicContact CD2-CB 3.39Å; F71-F88 HydrophobicContact CD2-CD2 4.26Å; F71-F88 AromaticContact CD2-CG 3.93Å; F71-F88 HydrophobicContact CD2-CG 3.93Å; F71-F88 HydrophobicContact CE1-CB 3.7Å; F71-F88 HydrophobicContact CE2-CB 3.43Å; F71-F88 VanDerWaalsContact CE2-CB 3.43Å; F71-F88 HydrophobicContact CE2-CG 4.44Å; F71-F88 HydrophobicContact CG-CB 3.49Å; F71-F88 VanDerWaalsContact CG-CB 3.49Å; F71-F88 HydrophobicContact CG-CD1 4.18Å; F71-F88 HydrophobicContact CG-CD2 4.28Å; F71-F88 AromaticContact CG-CG 3.72Å; F71-F88 HydrophobicContact CG-CG 3.72Å; F71-F88 HydrophobicContact CZ-CB 3.58Å; F71-A109 HydrophobicContact CD2-CB 4.12Å; F71-A109 HydrophobicContact CE2-CB 4.14Å; F71-F111 HydrophobicContact CD2-CE2 4.49Å; F71-F111 AromaticContact CD2-CZ 3.75Å; F71-F111 HydrophobicContact CD2-CZ 3.75Å; F71-F111 AromaticContact CE2-CE1 3.78Å; F71-F111 HydrophobicContact CE2-CE1 3.78Å; F71-F111 HydrophobicContact CE2-CE2 4.17Å; F71-F111 AromaticContact CE2-CZ 3.35Å; F71-F111 HydrophobicContact CE2-CZ 3.35Å; F71-F111 HydrophobicContact CZ-CE1 4.46Å; F71-F111 HydrophobicContact CZ-CZ 4.4Å
72R98.1Very high98.4Very high160 Ų16044.6 Ų44.660%0.60421%0.212SC*.Iπ-helixtrans-75.8-39.4-175.2-65.9177.6178.6143.51.6113.3E69 Q70 P77E69-R72 PolarHBondContact O-N 2.9Å; Q70-R72 VanDerWaalsContact C-N 3.29Å; Q70-R72 PolarHBondContact O-N 2.8Å; R72-P77 VanDerWaalsContact O-CD 3.28Å; R72-P77 WeakPolarHBondContact O-CD 3.11Å
73T98.2Very high98.3Very high86 Ų8646 Ų4653%0.52823%0.226SC..Iπ-helixtrans-96.1-22.8-170.660.80000113.3E69 P77E69-T73 HydrophobicContact CG-CG2 3.95Å; E69-T73 PolarHBondContact O-N 3.35Å; E69-T73 PolarHBondContact O-OG1 3.08Å; T73-P77 VanDerWaalsContact O-CG 3.29Å; T73-P77 WeakPolarHBondContact O-CG 3.28Å
74L98.5Very high98.3Very high18 Ų1846.5 Ų46.59%0.09423%0.228CC..Iπ-helixtrans-120.9-71.2-177.5179.676.6000111.9W42 K46 I50 Q70 Q76 P77 E78W42-L74 HydrophobicContact CZ2-CD2 3.8Å; K46-L74 HydrophobicContact CB-CD2 3.74Å; K46-L74 HydrophobicContact CD-CD1 4.45Å; K46-L74 HydrophobicContact CD-CD2 4.38Å; K46-L74 HydrophobicContact CG-CD2 4.41Å; I50-L74 HydrophobicContact CD1-CD2 4.38Å; I50-L74 HydrophobicContact CD1-CG 4.15Å; I50-L74 HydrophobicContact CG1-CD1 4.05Å; I50-L74 HydrophobicContact CG1-CD2 4.17Å; I50-L74 HydrophobicContact CG1-CG 4.1Å; Q70-L74 CarbonylContact O-C 3.57Å; Q70-L74 WeakPolarHBondContact O-CA 3.23Å; Q70-L74 VanDerWaalsContact O-CB 3.29Å; Q70-L74 WeakPolarHBondContact O-CB 3.28Å; Q70-L74 PolarHBondContact O-N 2.8Å; L74-Q76 PolarHBondContact O-N 3.31Å; L74-P77 VanDerWaalsContact O-CD 3.26Å; L74-P77 WeakPolarHBondContact O-CD 3.2Å; L74-P77 WeakPolarHBondContact O-CG 3.33Å; L74-E78 HydrophobicContact CD1-CG 4.08Å; L74-E78 WeakPolarHBondContact O-CB 3.45Å; L74-E78 WeakPolarHBondContact O-CG 3.46Å; L74-E78 PolarHBondContact O-N 2.64Å
75F98.7Very high98.3Very high0 Ų048 Ų480%024%0.241CC..Iπ-helixtrans-62.9-48-166.6-67.9-82.5000112.5V21 W42 I49 I50 I53 L63 V66 Q70 L79 F111V21-F75 HydrophobicContact CG2-CZ 4.1Å; W42-F75 HydrophobicContact CH2-CE2 4.15Å; W42-F75 HydrophobicContact CH2-CZ 4.13Å; W42-F75 HydrophobicContact CZ2-CE2 4.3Å; I49-F75 HydrophobicContact CG2-CE1 3.88Å; I49-F75 HydrophobicContact CG2-CZ 4.21Å; I50-F75 HydrophobicContact CD1-CD1 3.92Å; I50-F75 HydrophobicContact CD1-CE1 4.2Å; I53-F75 HydrophobicContact CD1-CD1 4.33Å; I53-F75 HydrophobicContact CD1-CE1 4.06Å; L63-F75 HydrophobicContact CD1-CD1 3.79Å; L63-F75 HydrophobicContact CD1-CE1 3.82Å; V66-F75 HydrophobicContact CG1-CD2 3.69Å; V66-F75 HydrophobicContact CG1-CE2 3.86Å; V66-F75 HydrophobicContact CG1-CG 4.47Å; V66-F75 HydrophobicContact CG2-CE2 4.45Å; Q70-F75 HydrophobicContact CB-CD2 4.22Å; Q70-F75 HydrophobicContact CB-CE2 4.07Å; Q70-F75 WeakPolarHBondContact O-CD2 3.28Å; Q70-F75 PolarHBondContact O-N 3.17Å; F75-L79 WeakPolarHBondContact O-CB 3.42Å; F75-L79 VanDerWaalsContact O-CG 3.31Å; F75-L79 WeakPolarHBondContact O-CG 3.28Å; F75-L79 PolarHBondContact O-N 3.35Å; F75-F111 HydrophobicContact CB-CE2 4.39Å; F75-F111 HydrophobicContact CB-CZ 3.75Å
76Q98.4Very high98.3Very high84 Ų8448.1 Ų48.139%0.39325%0.246SC..Hα-helixtrans-62.2-53179.7-173.7177.22800113.1F71 L74 K80F71-Q76 HydrophobicContact CE1-CB 4.26Å; F71-Q76 HydrophobicContact CZ-CB 4.32Å; F71-Q76 WeakPolarHBondContact O-CB 3.43Å; F71-Q76 PolarHBondContact O-N 3.31Å; L74-Q76 PolarHBondContact O-N 3.31Å; Q76-K80 WeakPolarHBondContact O-CB 3.3Å; Q76-K80 PolarHBondContact O-N 3.21Å
77P98.5Very high98.3Very high47 Ų4748.7 Ų48.731%0.30525%0.249SC..Hα-helixtrans-65.5-39.3179.722-31.7000113.1R72 T73 L74 Q81R72-P77 VanDerWaalsContact O-CD 3.28Å; R72-P77 WeakPolarHBondContact O-CD 3.11Å; T73-P77 VanDerWaalsContact O-CG 3.29Å; T73-P77 WeakPolarHBondContact O-CG 3.28Å; L74-P77 VanDerWaalsContact O-CD 3.26Å; L74-P77 WeakPolarHBondContact O-CD 3.2Å; L74-P77 WeakPolarHBondContact O-CG 3.33Å; P77-Q81 WeakPolarHBondContact O-CG 3.46Å; P77-Q81 PolarHBondContact O-N 2.64Å
78E98.4Very high98.4Very high52 Ų5249.8 Ų49.824%0.24325%0.253CS..Hα-helixtrans-66.4-47.2179.3-69.9-63.7161.900112I50 R54 L74 Q81I50-E78 HydrophobicContact CD1-CB 4.16Å; I50-E78 HydrophobicContact CD1-CG 4.43Å; I50-E78 HydrophobicContact CG2-CB 4.41Å; I50-E78 HydrophobicContact CG2-CG 4.49Å; R54-E78 IonicContact CZ-OE2 3.59Å; R54-E78 IonicContact NH2-OE2 2.7Å; R54-E78 PolarHBondContact NH2-OE2 3.11Å; L74-E78 HydrophobicContact CD1-CG 4.08Å; L74-E78 WeakPolarHBondContact O-CB 3.45Å; L74-E78 WeakPolarHBondContact O-CG 3.46Å; L74-E78 PolarHBondContact O-N 2.64Å; E78-Q81 PolarHBondContact O-N 3.43Å
79L98.4Very high98.4Very high1 Ų152.1 Ų52.11%0.00526%0.264CS..Hα-helixtrans-73.2-29.7179.8-68.7174.2000112I53 I61 F75 Q81 L82 G83 Y84 F111I53-L79 HydrophobicContact CG2-CD2 3.63Å; I61-L79 HydrophobicContact CD1-CD2 4.33Å; F75-L79 WeakPolarHBondContact O-CB 3.42Å; F75-L79 VanDerWaalsContact O-CG 3.31Å; F75-L79 WeakPolarHBondContact O-CG 3.28Å; F75-L79 PolarHBondContact O-N 3.35Å; L79-Q81 VanDerWaalsContact C-N 3.29Å; L79-Q81 PolarHBondContact O-N 3.39Å; L79-L82 HydrophobicContact CD2-CD1 3.93Å; L79-L82 CarbonylContact O-C 3.57Å; L79-L82 WeakPolarHBondContact O-CA 3.45Å; L79-L82 WeakPolarHBondContact O-CB 3.37Å; L79-L82 PolarHBondContact O-N 3.46Å; L79-G83 PolarHBondContact O-N 2.99Å; L79-Y84 HydrophobicContact CB-CD2 4.18Å; L79-Y84 HydrophobicContact CB-CG 4.27Å; L79-Y84 HydrophobicContact CD2-CD2 4.1Å; L79-Y84 HydrophobicContact CD2-CE2 4.26Å; L79-Y84 WeakPolarHBondContact O-CB 3.45Å; L79-Y84 WeakPolarHBondContact O-CD2 3.4Å; L79-Y84 PolarHBondContact O-N 3.49Å; L79-F111 HydrophobicContact CB-CD1 4.11Å; L79-F111 HydrophobicContact CB-CE1 4.29Å; L79-F111 HydrophobicContact CD1-CB 4.33Å; L79-F111 HydrophobicContact CD1-CD1 3.55Å; L79-F111 HydrophobicContact CD1-CD2 3.67Å; L79-F111 HydrophobicContact CD1-CE1 3.64Å; L79-F111 HydrophobicContact CD1-CE2 3.74Å; L79-F111 HydrophobicContact CD1-CG 3.58Å; L79-F111 HydrophobicContact CD1-CZ 3.72Å; L79-F111 HydrophobicContact CG-CD1 4.49Å
80K98.5Very high98.4Very high154 Ų15450.2 Ų50.267%0.6726%0.258SS*.Hα-helixtrans-60.5-38.5173.3-175177.9-178.9-178.40112.4Q76 L82 G83 Y84Q76-K80 WeakPolarHBondContact O-CB 3.3Å; Q76-K80 PolarHBondContact O-N 3.21Å; K80-L82 PolarHBondContact O-N 3.25Å; K80-G83 PolarHBondContact O-N 3.06Å; K80-G83 VanDerWaalsContact O-N 3.07Å; K80-Y84 WeakPolarHBondContact CA-O 3.39Å
81Q98Very high98.3Very high148 Ų14849.6 Ų49.669%0.69226%0.255SS*.Hα-helixtrans-63.2-26.2174.9-68.4174.241.500112.5P77 E78 L79 G83P77-Q81 WeakPolarHBondContact O-CG 3.46Å; P77-Q81 PolarHBondContact O-N 2.64Å; E78-Q81 PolarHBondContact O-N 3.43Å; L79-Q81 VanDerWaalsContact C-N 3.29Å; L79-Q81 PolarHBondContact O-N 3.39Å; Q81-G83 VanDerWaalsContact C-N 3.3Å
82L97.4Very high98Very high63 Ų6349.6 Ų49.633%0.3326%0.257SS..THydrogen-bonded Turntrans-90.79.6177.5-56168.4000112.7R54 L79 K80 Y84 K113R54-L82 HydrophobicContact CG-CD1 3.42Å; R54-L82 VanDerWaalsContact CG-CD1 3.42Å; R54-L82 HydrophobicContact CG-CD2 4.44Å; L79-L82 HydrophobicContact CD2-CD1 3.93Å; L79-L82 CarbonylContact O-C 3.57Å; L79-L82 WeakPolarHBondContact O-CA 3.45Å; L79-L82 WeakPolarHBondContact O-CB 3.37Å; L79-L82 PolarHBondContact O-N 3.46Å; K80-L82 PolarHBondContact O-N 3.25Å; L82-Y84 HydrophobicContact CB-CD2 3.76Å; L82-Y84 HydrophobicContact CB-CE2 3.81Å; L82-K113 PolarHBondContact O-NZ 2.71Å
83G98.3Very high97.7Very high30 Ų3044.3 Ų44.331%0.30924%0.237SC..THydrogen-bonded Turntrans8123.8178.200000114.5L79 K80 Q81 V114L79-G83 PolarHBondContact O-N 2.99Å; K80-G83 PolarHBondContact O-N 3.06Å; K80-G83 VanDerWaalsContact O-N 3.07Å; Q81-G83 VanDerWaalsContact C-N 3.3Å; G83-V114 WeakPolarHBondContact O-CG2 3.26Å; G83-V114 PolarHBondContact O-N 3.42Å
84Y98.8Very high97.2Very high9 Ų940.6 Ų40.64%0.03522%0.215CC..EExtended strand (participates in β ladder)trans-97.2147.8172.4-63.6-97000112.1A58 I61 L79 K80 L82 F111 W112 K113A58-Y84 WeakPolarHBondContact O-CE1 3.28Å; A58-Y84 PolarHBondContact O-OH 2.85Å; I61-Y84 HydrophobicContact CD1-CD1 4.09Å; I61-Y84 HydrophobicContact CD1-CE1 3.53Å; I61-Y84 HydrophobicContact CD1-CE2 4.45Å; I61-Y84 HydrophobicContact CG1-CE1 4.21Å; L79-Y84 HydrophobicContact CB-CD2 4.18Å; L79-Y84 HydrophobicContact CB-CG 4.27Å; L79-Y84 HydrophobicContact CD2-CD2 4.1Å; L79-Y84 HydrophobicContact CD2-CE2 4.26Å; L79-Y84 WeakPolarHBondContact O-CB 3.45Å; L79-Y84 WeakPolarHBondContact O-CD2 3.4Å; L79-Y84 PolarHBondContact O-N 3.49Å; K80-Y84 WeakPolarHBondContact CA-O 3.39Å; L82-Y84 HydrophobicContact CB-CD2 3.76Å; L82-Y84 HydrophobicContact CB-CE2 3.81Å; Y84-F111 HydrophobicContact CD1-CB 4.09Å; Y84-W112 VanDerWaalsContact CA-O 3.24Å; Y84-W112 WeakPolarHBondContact CA-O 3.18Å; Y84-W112 VanDerWaalsContact CD1-C 3.47Å; Y84-K113 HydrophobicContact CD1-CD 4.11Å; Y84-K113 HydrophobicContact CD1-CG 4.2Å; Y84-K113 HydrophobicContact CD2-CD 4.13Å; Y84-K113 HydrophobicContact CE1-CD 3.73Å; Y84-K113 HydrophobicContact CE1-CG 3.71Å; Y84-K113 HydrophobicContact CE2-CD 3.79Å; Y84-K113 HydrophobicContact CG-CD 4.29Å; Y84-K113 WeakPolarHBondContact OH-CE 3.3Å; Y84-K113 PolarHBondContact OH-NZ 3.01Å
85A98.8Very high96.8Very high33 Ų3346 Ų4627%0.27324%0.238SC..EExtended strand (participates in β ladder)trans-106.1162.4153.600000108.4F111 W112 V114A85-F111 CarbonylContact O-C 3.52Å; A85-F111 WeakPolarHBondContact O-CA 3.31Å; A85-W112 HydrophobicContact CB-CD2 4.45Å; A85-W112 HydrophobicContact CB-CH2 4.16Å; A85-W112 HydrophobicContact CB-CZ2 3.47Å; A85-W112 VanDerWaalsContact CB-CZ2 3.47Å; A85-W112 PolarHBondContact N-O 3.29Å; A85-W112 PolarHBondContact O-N 2.73Å; A85-V114 HydrophobicContact CB-CG1 3.61Å
86G98.6Very high96.4Very high16 Ų1652.1 Ų52.117%0.16528%0.276CS..EExtended strand (participates in β ladder)trans-159.7158.6177.800000114I110G86-I110 CarbonylContact C-O 3.43Å; G86-I110 WeakPolarHBondContact CA-O 3.43Å
87I98.9Very high96Very high13 Ų1350.1 Ų50.17%0.06727%0.267CS..EExtended strand (participates in β ladder)trans-123.2155.2175.758.6171.6000109.6A109 I110 W112 M119 Q122 L153 A155I87-A109 CarbonylContact O-C 3.58Å; I87-A109 VanDerWaalsContact O-CA 3.23Å; I87-A109 WeakPolarHBondContact O-CA 3.39Å; I87-I110 HydrophobicContact CG1-CB 4.06Å; I87-I110 PolarHBondContact N-O 3.01Å; I87-I110 PolarHBondContact O-N 2.83Å; I87-W112 HydrophobicContact CG1-CZ3 4.21Å; I87-W112 HydrophobicContact CG2-CH2 3.95Å; I87-W112 HydrophobicContact CG2-CZ3 4.12Å; I87-M119 HydrophobicContact CG2-SD 3.68Å; I87-Q122 HydrophobicContact CD1-CB 3.67Å; I87-Q122 VanDerWaalsContact CG2-OE1 3.22Å; I87-L153 HydrophobicContact CD1-CD1 3.92Å; I87-L153 HydrophobicContact CD1-CD2 4.22Å; I87-L153 HydrophobicContact CD1-CG 4.09Å; I87-L153 HydrophobicContact CG1-CD2 4.06Å; I87-L153 HydrophobicContact CG1-CG 4.47Å; I87-A155 HydrophobicContact CD1-CB 3.95Å
88F98.8Very high95.7Very high29 Ų2950 Ų5013%0.12727%0.273CS..EExtended strand (participates in β ladder)trans-147.6142.2-180165.7-97.2000110.3V66 T68 F71 A90 C108 A109V66-F88 HydrophobicContact CB-CD2 4.24Å; V66-F88 HydrophobicContact CB-CE2 4.05Å; V66-F88 HydrophobicContact CG1-CD2 4.18Å; V66-F88 HydrophobicContact CG1-CE2 4.17Å; V66-F88 WeakPolarHBondContact O-CE2 3.36Å; V66-F88 WeakPolarHBondContact O-CZ 3.42Å; T68-F88 HydrophobicContact CG2-CE1 4.12Å; T68-F88 WeakPolarHBondContact OG1-CE1 3.09Å; F71-F88 HydrophobicContact CB-CB 4.31Å; F71-F88 HydrophobicContact CB-CD1 4.23Å; F71-F88 HydrophobicContact CB-CD2 4.27Å; F71-F88 HydrophobicContact CB-CG 4Å; F71-F88 HydrophobicContact CD1-CB 3.64Å; F71-F88 HydrophobicContact CD1-CD1 4.26Å; F71-F88 HydrophobicContact CD1-CG 4.09Å; F71-F88 HydrophobicContact CD2-CB 3.39Å; F71-F88 HydrophobicContact CD2-CD2 4.26Å; F71-F88 AromaticContact CD2-CG 3.93Å; F71-F88 HydrophobicContact CD2-CG 3.93Å; F71-F88 HydrophobicContact CE1-CB 3.7Å; F71-F88 HydrophobicContact CE2-CB 3.43Å; F71-F88 VanDerWaalsContact CE2-CB 3.43Å; F71-F88 HydrophobicContact CE2-CG 4.44Å; F71-F88 HydrophobicContact CG-CB 3.49Å; F71-F88 VanDerWaalsContact CG-CB 3.49Å; F71-F88 HydrophobicContact CG-CD1 4.18Å; F71-F88 HydrophobicContact CG-CD2 4.28Å; F71-F88 AromaticContact CG-CG 3.72Å; F71-F88 HydrophobicContact CG-CG 3.72Å; F71-F88 HydrophobicContact CZ-CB 3.58Å; F88-A90 HydrophobicContact CE1-CB 3.93Å; F88-A90 HydrophobicContact CZ-CB 3.88Å; F88-C108 WeakPolarHBondContact CA-O 3.23Å; F88-C108 VanDerWaalsContact CD2-O 3.26Å; F88-C108 WeakPolarHBondContact CD2-O 3.26Å; F88-A109 HydrophobicContact CB-CB 4.35Å; F88-A109 HydrophobicContact CD2-CB 4.22Å
89E98.6Very high95.2Very high56 Ų5654.6 Ų54.626%0.26230%0.295SS..EExtended strand (participates in β ladder)trans-134.4133.6168.6-69.5-67.3173.900109.3G107 C108 Q122 L124 I151 L153E89-G107 VanDerWaalsContact O-CA 3.3Å; E89-G107 WeakPolarHBondContact O-CA 3.34Å; E89-C108 PolarHBondContact N-O 2.98Å; E89-C108 VanDerWaalsContact N-O 3.1Å; E89-C108 PolarHBondContact O-N 3.44Å; E89-Q122 PolarHBondContact OE1-NE2 3.14Å; E89-L124 HydrophobicContact CB-CD1 3.73Å; E89-L124 HydrophobicContact CG-CB 4.25Å; E89-L124 HydrophobicContact CG-CD1 4.01Å; E89-L124 HydrophobicContact CG-CD2 4.39Å; E89-L124 HydrophobicContact CG-CG 4.42Å; E89-I151 HydrophobicContact CB-CD1 4.06Å; E89-I151 WeakPolarHBondContact O-CD1 3.49Å; E89-L153 HydrophobicContact CB-CD1 4.28Å; E89-L153 HydrophobicContact CG-CD1 3.7Å
90A97.8Very high94.9Very high16 Ų1660 Ų6013%0.13232%0.32CS..EExtended strand (participates in β ladder)trans-81.1155.1176.600000110.9T68 F88 A94 V105T68-A90 WeakPolarHBondContact OG1-CB 3.42Å; F88-A90 HydrophobicContact CE1-CB 3.93Å; F88-A90 HydrophobicContact CZ-CB 3.88Å; A90-A94 HydrophobicContact CB-CB 3.81Å; A90-V105 HydrophobicContact CB-CB 4.5Å; A90-V105 HydrophobicContact CB-CG1 4.1Å
91K96.6Very high94.6Very high10 Ų1058 Ų584%0.04331%0.314CS..  trans-53.5147.7170.9-75.3174.4179.9158.70111.4R93 A94 V105 D106 D149K91-R93 HydrophobicContact CB-CG 4.47Å; K91-R93 VanDerWaalsContact CD-NH1 3.27Å; K91-R93 PolarHBondContact O-N 3.19Å; K91-A94 VanDerWaalsContact O-CB 3.32Å; K91-A94 WeakPolarHBondContact O-CB 3.34Å; K91-A94 PolarHBondContact O-N 2.94Å; K91-V105 HydrophobicContact CB-CG1 4.11Å; K91-D106 WeakPolarHBondContact CE-OD2 3.41Å; K91-D106 WeakPolarHBondContact CG-O 3.37Å; K91-D106 PolarHBondContact N-O 2.86Å; K91-D106 IonicContact NZ-OD1 3.21Å; K91-D106 PolarHBondContact NZ-OD1 3.11Å; K91-D106 IonicContact NZ-OD2 2.83Å; K91-D106 PolarHBondContact NZ-OD2 2.96Å; K91-D149 WeakPolarHBondContact CB-O 3.23Å
92S92.5Very high94.3Very high17 Ų1755.3 Ų55.312%0.11930%0.297CS..G310 helixtrans-56.8-25.9-167.6-67.30000114.6A94 K95 E126 D149S92-A94 PolarHBondContact O-N 3.45Å; S92-A94 VanDerWaalsContact O-N 3.14Å; S92-K95 WeakPolarHBondContact O-CB 3.34Å; S92-K95 PolarHBondContact O-N 3.47Å; S92-K95 VanDerWaalsContact O-N 3.13Å; S92-E126 WeakPolarHBondContact CB-OE1 3.46Å; S92-E126 WeakPolarHBondContact OG-CG 3.36Å; S92-E126 PolarHBondContact OG-OE1 2.8Å; S92-D149 PolarHBondContact N-O 3.47Å
93R91Very high94.2Very high48 Ų4854.9 Ų54.918%0.18129%0.292CS..G310 helixtrans-56.4-26.4175.267178.8176.9-103.43.1113.8K91 K95 T96 M97 V105 D106 D149K91-R93 HydrophobicContact CB-CG 4.47Å; K91-R93 VanDerWaalsContact CD-NH1 3.27Å; K91-R93 PolarHBondContact O-N 3.19Å; R93-K95 PolarHBondContact O-N 3.01Å; R93-T96 PolarHBondContact O-N 3.03Å; R93-T96 VanDerWaalsContact O-N 3.09Å; R93-T96 PolarHBondContact O-OG1 3.18Å; R93-M97 HydrophobicContact CB-SD 4.41Å; R93-M97 HydrophobicContact CG-SD 4.1Å; R93-M97 WeakPolarHBondContact O-CG 3.35Å; R93-M97 PolarHBondContact O-N 3.28Å; R93-V105 HydrophobicContact CG-CG1 3.88Å; R93-V105 HydrophobicContact CG-CG2 4.31Å; R93-D106 IonicContact CZ-OD1 3.65Å; R93-D106 IonicContact NH2-OD1 3.69Å; R93-D106 PolarHBondContact NH2-OD1 3.31Å; R93-D149 HydrophobicContact CB-CB 4.47Å; R93-D149 WeakPolarHBondContact CB-OD2 3.41Å; R93-D149 WeakPolarHBondContact CD-OD2 3.39Å; R93-D149 WeakPolarHBondContact CG-OD2 3.46Å; R93-D149 IonicContact CZ-OD2 3.97Å; R93-D149 IonicContact NE-OD2 3.44Å; R93-D149 IonicContact NH1-OD1 3.66Å; R93-D149 IonicContact NH1-OD2 3.57Å; R93-D149 PolarHBondContact NH1-OD2 2.67Å
94A88.4Confident94Very high9 Ų958.8 Ų58.87%0.07430%0.298CS..G310 helixtrans-52.3-30.2175.800000113.1A90 K91 S92 T96 R102 V105A90-A94 HydrophobicContact CB-CB 3.81Å; K91-A94 VanDerWaalsContact O-CB 3.32Å; K91-A94 WeakPolarHBondContact O-CB 3.34Å; K91-A94 PolarHBondContact O-N 2.94Å; S92-A94 PolarHBondContact O-N 3.45Å; S92-A94 VanDerWaalsContact O-N 3.14Å; A94-T96 VanDerWaalsContact C-N 3.34Å; A94-T96 PolarHBondContact O-N 3.21Å; A94-R102 HydrophobicContact CB-CG 3.93Å; A94-R102 PolarHBondContact O-NE 2.89Å; A94-V105 HydrophobicContact CB-CB 4.21Å; A94-V105 HydrophobicContact CB-CG1 4.01Å; A94-V105 HydrophobicContact CB-CG2 4.34Å
95K89.8Confident93.9Very high130 Ų13058.4 Ų58.457%0.56530%0.297SS*.G310 helixtrans-70.6-25.8-177.6-65.2179.2176.5178.60113.9S92 R93 E126S92-K95 WeakPolarHBondContact O-CB 3.34Å; S92-K95 PolarHBondContact O-N 3.47Å; S92-K95 VanDerWaalsContact O-N 3.13Å; R93-K95 PolarHBondContact O-N 3.01Å; K95-E126 WeakPolarHBondContact CE-OE1 3.42Å; K95-E126 IonicContact NZ-OE1 2.74Å; K95-E126 PolarHBondContact NZ-OE1 3.43Å; K95-E126 IonicContact NZ-OE2 2.73Å; K95-E126 PolarHBondContact NZ-OE2 3.3Å
96T89.5Confident93.9Very high130 Ų13056.8 Ų56.880%0.79828%0.284SS*.THydrogen-bonded Turntrans-105.2-6.3-17857.10000113.1R93 A94R93-T96 PolarHBondContact O-N 3.03Å; R93-T96 VanDerWaalsContact O-N 3.09Å; R93-T96 PolarHBondContact O-OG1 3.18Å; A94-T96 VanDerWaalsContact C-N 3.34Å; A94-T96 PolarHBondContact O-N 3.21Å
97M90.6Very high93.9Very high42 Ų4256 Ų5621%0.20728%0.276CS..SBendtrans-89153.6179.1-65.8178.187.200111.9R93 E101 R102 V105R93-M97 HydrophobicContact CB-SD 4.41Å; R93-M97 HydrophobicContact CG-SD 4.1Å; R93-M97 WeakPolarHBondContact O-CG 3.35Å; R93-M97 PolarHBondContact O-N 3.28Å; M97-E101 HydrophobicContact CB-CB 4.42Å; M97-E101 HydrophobicContact CE-CB 3.54Å; M97-E101 HydrophobicContact CE-CG 4.36Å; M97-E101 WeakPolarHBondContact CE-OE2 3.4Å; M97-R102 PolarHBondContact O-NH2 2.82Å; M97-V105 HydrophobicContact CE-CG2 4.46Å; M97-V105 HydrophobicContact SD-CG2 3.52Å; M97-V105 VanDerWaalsContact SD-CG2 3.52Å
98G91.8Very high93.9Very high43 Ų4355.4 Ų55.444%0.44327%0.273SS..  trans-64161.8171.100000112.1E100 E101 R102G98-E100 VanDerWaalsContact C-N 3.34Å; G98-E100 PolarHBondContact O-N 2.71Å; G98-E101 PolarHBondContact O-N 3.03Å; G98-R102 WeakPolarHBondContact O-CB 3.46Å; G98-R102 PolarHBondContact O-N 2.63Å
99E89.2Confident93.9Very high149 Ų14954 Ų5470%0.69627%0.267SS*.Hα-helixtrans-60.1-38.8-172.6-67.5-171.1158.900113.9
100E91.4Very high93.9Very high114 Ų11451.4 Ų51.453%0.53326%0.255SS..Hα-helixtrans-67.6-46.1179.5-69.6-55.2126.800112.2G98 R102 K103 Y104G98-E100 VanDerWaalsContact C-N 3.34Å; G98-E100 PolarHBondContact O-N 2.71Å; E100-R102 VanDerWaalsContact C-N 3.3Å; E100-R102 PolarHBondContact O-N 3.19Å; E100-K103 WeakPolarHBondContact O-CB 3.27Å; E100-K103 PolarHBondContact O-N 3.49Å; E100-K103 IonicContact OE1-NZ 3.72Å; E100-K103 PolarHBondContact OE1-NZ 2.8Å; E100-K103 IonicContact OE2-NZ 2.62Å; E100-K103 PolarHBondContact OE2-NZ 2.8Å; E100-Y104 WeakPolarHBondContact O-CD2 3.49Å; E100-Y104 WeakPolarHBondContact O-CE2 3.41Å
101E91.2Very high94Very high114 Ų11450.7 Ų50.753%0.53325%0.248SC..Hα-helixtrans-70.2-30.8179.6-56.5-179.1148.200112.1M97 G98 K103 Y104M97-E101 HydrophobicContact CB-CB 4.42Å; M97-E101 HydrophobicContact CE-CB 3.54Å; M97-E101 HydrophobicContact CE-CG 4.36Å; M97-E101 WeakPolarHBondContact CE-OE2 3.4Å; G98-E101 PolarHBondContact O-N 3.03Å; E101-K103 PolarHBondContact O-N 2.83Å; E101-Y104 PolarHBondContact O-N 2.88Å; E101-Y104 VanDerWaalsContact O-N 3.14Å
102R93.1Very high94.1Very high90 Ų9050.8 Ų50.834%0.3425%0.249SC..Hα-helixtrans-58.5-31.1177.8-171.8-177-62.8148.36.5112.2T68 A94 M97 G98 E100 Y104 V105T68-R102 WeakPolarHBondContact CB-O 3.23Å; T68-R102 PolarHBondContact OG1-O 2.99Å; A94-R102 HydrophobicContact CB-CG 3.93Å; A94-R102 PolarHBondContact O-NE 2.89Å; M97-R102 PolarHBondContact O-NH2 2.82Å; G98-R102 WeakPolarHBondContact O-CB 3.46Å; G98-R102 PolarHBondContact O-N 2.63Å; E100-R102 VanDerWaalsContact C-N 3.3Å; E100-R102 PolarHBondContact O-N 3.19Å; R102-Y104 PolarHBondContact O-N 3.31Å; R102-V105 PolarHBondContact O-N 2.88Å; R102-V105 VanDerWaalsContact O-N 3.14Å
103K94.1Very high94.4Very high55 Ų5551.6 Ų51.624%0.23925%0.25CC..THydrogen-bonded Turntrans-57.1-32.9178-69.8175.1-171.7170.40112.8T68 E69 E100 E101T68-K103 WeakPolarHBondContact CB-O 3.41Å; T68-K103 PolarHBondContact N-O 3.35Å; E69-K103 HydrophobicContact CB-CB 3.94Å; E69-K103 HydrophobicContact CB-CG 4.44Å; E69-K103 PolarHBondContact N-O 3.17Å; E100-K103 WeakPolarHBondContact O-CB 3.27Å; E100-K103 PolarHBondContact O-N 3.49Å; E100-K103 IonicContact OE1-NZ 3.72Å; E100-K103 PolarHBondContact OE1-NZ 2.8Å; E100-K103 IonicContact OE2-NZ 2.62Å; E100-K103 PolarHBondContact OE2-NZ 2.8Å; E101-K103 PolarHBondContact O-N 2.83Å
104Y95.1Very high94.7Very high111 Ų11152.2 Ų52.244%0.43526%0.259SS..THydrogen-bonded Turntrans-99.47-176.7-50.7-74.1000113E100 E101 R102 D106E100-Y104 WeakPolarHBondContact O-CD2 3.49Å; E100-Y104 WeakPolarHBondContact O-CE2 3.41Å; E101-Y104 PolarHBondContact O-N 2.88Å; E101-Y104 VanDerWaalsContact O-N 3.14Å; R102-Y104 PolarHBondContact O-N 3.31Å; Y104-D106 PolarHBondContact O-N 2.86Å
105V96.9Very high95.1Very high1 Ų155.7 Ų55.71%0.00628%0.276CS..  trans-77.4121.8171.9-179.30000108.3T68 A90 K91 R93 A94 M97 R102T68-V105 PolarHBondContact N-O 2.82Å; T68-V105 PolarHBondContact OG1-O 2.82Å; A90-V105 HydrophobicContact CB-CB 4.5Å; A90-V105 HydrophobicContact CB-CG1 4.1Å; K91-V105 HydrophobicContact CB-CG1 4.11Å; R93-V105 HydrophobicContact CG-CG1 3.88Å; R93-V105 HydrophobicContact CG-CG2 4.31Å; A94-V105 HydrophobicContact CB-CB 4.21Å; A94-V105 HydrophobicContact CB-CG1 4.01Å; A94-V105 HydrophobicContact CB-CG2 4.34Å; M97-V105 HydrophobicContact CE-CG2 4.46Å; M97-V105 HydrophobicContact SD-CG2 3.52Å; M97-V105 VanDerWaalsContact SD-CG2 3.52Å; R102-V105 PolarHBondContact O-N 2.88Å; R102-V105 VanDerWaalsContact O-N 3.14Å
106D98Very high95.5Very high0 Ų050.7 Ų50.70%026%0.255CS..EExtended strand (participates in β ladder)trans-77.1162.3175.678.2-66.3000112.4C23 V66 K91 R93 Y104C23-D106 HydrophobicContact CB-CB 4.07Å; V66-D106 CarbonylContact O-C 3.47Å; V66-D106 VanDerWaalsContact O-CA 3.25Å; V66-D106 WeakPolarHBondContact O-CA 3.25Å; K91-D106 WeakPolarHBondContact CE-OD2 3.41Å; K91-D106 WeakPolarHBondContact CG-O 3.37Å; K91-D106 PolarHBondContact N-O 2.86Å; K91-D106 IonicContact NZ-OD1 3.21Å; K91-D106 PolarHBondContact NZ-OD1 3.11Å; K91-D106 IonicContact NZ-OD2 2.83Å; K91-D106 PolarHBondContact NZ-OD2 2.96Å; R93-D106 IonicContact CZ-OD1 3.65Å; R93-D106 IonicContact NH2-OD1 3.69Å; R93-D106 PolarHBondContact NH2-OD1 3.31Å; Y104-D106 PolarHBondContact O-N 2.86Å
107G98.4Very high95.9Very high0 Ų044.5 Ų44.50%022%0.217CC..EExtended strand (participates in β ladder)trans-167-157.2179.600000112.5E65 V66 E89E65-G107 PolarHBondContact N-O 3.41Å; V66-G107 PolarHBondContact N-O 3.02Å; V66-G107 VanDerWaalsContact N-O 3.14Å; V66-G107 PolarHBondContact O-N 2.87Å; E89-G107 VanDerWaalsContact O-CA 3.3Å; E89-G107 WeakPolarHBondContact O-CA 3.34Å
108C98.8Very high96.3Very high0 Ų046 Ų460%023%0.225CC..EExtended strand (participates in β ladder)trans-113.5144.4-179.6-62.20000110.8L63 F88 E89 L153 T189L63-C108 CarbonylContact O-C 3.58Å; L63-C108 VanDerWaalsContact O-CA 3.28Å; L63-C108 WeakPolarHBondContact O-CA 3.31Å; F88-C108 WeakPolarHBondContact CA-O 3.23Å; F88-C108 VanDerWaalsContact CD2-O 3.26Å; F88-C108 WeakPolarHBondContact CD2-O 3.26Å; E89-C108 PolarHBondContact N-O 2.98Å; E89-C108 VanDerWaalsContact N-O 3.1Å; E89-C108 PolarHBondContact O-N 3.44Å; C108-L153 HydrophobicContact CB-CB 4.2Å; C108-L153 VanDerWaalsContact O-CD2 3.23Å; C108-L153 WeakPolarHBondContact O-CD2 3.28Å; C108-T189 HydrophobicContact CB-CG2 3.75Å
109A98.9Very high96.6Very high0 Ų047.6 Ų47.60%022%0.222CC..EExtended strand (participates in β ladder)trans-127.1147174.100000111.6T62 L63 V66 F71 I87 F88 F111T62-A109 CarbonylContact C-O 3.5Å; T62-A109 WeakPolarHBondContact CA-O 3.37Å; L63-A109 HydrophobicContact CB-CB 4.39Å; L63-A109 PolarHBondContact N-O 2.91Å; L63-A109 PolarHBondContact O-N 2.87Å; V66-A109 HydrophobicContact CG2-CB 4.18Å; F71-A109 HydrophobicContact CD2-CB 4.12Å; F71-A109 HydrophobicContact CE2-CB 4.14Å; I87-A109 CarbonylContact O-C 3.58Å; I87-A109 VanDerWaalsContact O-CA 3.23Å; I87-A109 WeakPolarHBondContact O-CA 3.39Å; F88-A109 HydrophobicContact CB-CB 4.35Å; F88-A109 HydrophobicContact CD2-CB 4.22Å; A109-F111 HydrophobicContact CB-CD2 4.32Å; A109-F111 HydrophobicContact CB-CE2 3.63Å; A109-F111 HydrophobicContact CB-CZ 4.29Å
110I98.9Very high97Very high0 Ų043.3 Ų43.30%020%0.204CC..EExtended strand (participates in β ladder)trans-124.7125.3170-56.4177.7000107.8V60 I61 T62 G86 I87 W112 L153 A155 V187 T189V60-I110 HydrophobicContact CG1-CG2 4.48Å; I61-I110 CarbonylContact O-C 3.57Å; I61-I110 WeakPolarHBondContact O-CA 3.29Å; T62-I110 HydrophobicContact CG2-CG1 4.36Å; G86-I110 CarbonylContact C-O 3.43Å; G86-I110 WeakPolarHBondContact CA-O 3.43Å; I87-I110 HydrophobicContact CG1-CB 4.06Å; I87-I110 PolarHBondContact N-O 3.01Å; I87-I110 PolarHBondContact O-N 2.83Å; I110-W112 HydrophobicContact CG2-CE3 4.46Å; I110-L153 HydrophobicContact CD1-CG 4.1Å; I110-L153 HydrophobicContact CG1-CD2 4.22Å; I110-L153 HydrophobicContact CG1-CG 4.3Å; I110-A155 HydrophobicContact CD1-CB 4.12Å; I110-A155 HydrophobicContact CG2-CB 4.44Å; I110-V187 HydrophobicContact CD1-CG1 4.39Å; I110-V187 WeakPolarHBondContact CD1-O 3.42Å; I110-V187 HydrophobicContact CG2-CG1 4.24Å; I110-T189 HydrophobicContact CD1-CG2 3.99Å; I110-T189 HydrophobicContact CG1-CG2 3.63Å
111F98.9Very high97.3Very high1 Ų141.7 Ų41.70%0.00420%0.195CC..EExtended strand (participates in β ladder)trans-115.6150.6171.3-59.2-94.9000110.7V60 I61 L63 F71 F75 L79 Y84 A85 A109V60-F111 CarbonylContact C-O 3.54Å; V60-F111 WeakPolarHBondContact CA-O 3.48Å; I61-F111 HydrophobicContact CB-CB 4.22Å; I61-F111 PolarHBondContact N-O 2.84Å; I61-F111 PolarHBondContact O-N 2.97Å; L63-F111 HydrophobicContact CD1-CD2 4.43Å; L63-F111 HydrophobicContact CD1-CE2 3.98Å; F71-F111 HydrophobicContact CD2-CE2 4.49Å; F71-F111 AromaticContact CD2-CZ 3.75Å; F71-F111 HydrophobicContact CD2-CZ 3.75Å; F71-F111 AromaticContact CE2-CE1 3.78Å; F71-F111 HydrophobicContact CE2-CE1 3.78Å; F71-F111 HydrophobicContact CE2-CE2 4.17Å; F71-F111 AromaticContact CE2-CZ 3.35Å; F71-F111 HydrophobicContact CE2-CZ 3.35Å; F71-F111 HydrophobicContact CZ-CE1 4.46Å; F71-F111 HydrophobicContact CZ-CZ 4.4Å; F75-F111 HydrophobicContact CB-CE2 4.39Å; F75-F111 HydrophobicContact CB-CZ 3.75Å; L79-F111 HydrophobicContact CB-CD1 4.11Å; L79-F111 HydrophobicContact CB-CE1 4.29Å; L79-F111 HydrophobicContact CD1-CB 4.33Å; L79-F111 HydrophobicContact CD1-CD1 3.55Å; L79-F111 HydrophobicContact CD1-CD2 3.67Å; L79-F111 HydrophobicContact CD1-CE1 3.64Å; L79-F111 HydrophobicContact CD1-CE2 3.74Å; L79-F111 HydrophobicContact CD1-CG 3.58Å; L79-F111 HydrophobicContact CD1-CZ 3.72Å; L79-F111 HydrophobicContact CG-CD1 4.49Å; Y84-F111 HydrophobicContact CD1-CB 4.09Å; A85-F111 CarbonylContact O-C 3.52Å; A85-F111 WeakPolarHBondContact O-CA 3.31Å; A109-F111 HydrophobicContact CB-CD2 4.32Å; A109-F111 HydrophobicContact CB-CE2 3.63Å; A109-F111 HydrophobicContact CB-CZ 4.29Å
112W98.9Very high97.7Very high13 Ų1339.8 Ų39.85%0.04919%0.187CC..EExtended strand (participates in β ladder)trans-145.1148.5175.663.690.1000111.2D59 V60 Y84 A85 I87 I110 V114 F117 M119 L157D59-W112 CarbonylContact O-C 3.46Å; D59-W112 VanDerWaalsContact O-CA 3.29Å; D59-W112 WeakPolarHBondContact O-CA 3.45Å; V60-W112 HydrophobicContact CG2-CB 4.49Å; Y84-W112 VanDerWaalsContact CA-O 3.24Å; Y84-W112 WeakPolarHBondContact CA-O 3.18Å; Y84-W112 VanDerWaalsContact CD1-C 3.47Å; A85-W112 HydrophobicContact CB-CD2 4.45Å; A85-W112 HydrophobicContact CB-CH2 4.16Å; A85-W112 HydrophobicContact CB-CZ2 3.47Å; A85-W112 VanDerWaalsContact CB-CZ2 3.47Å; A85-W112 PolarHBondContact N-O 3.29Å; A85-W112 PolarHBondContact O-N 2.73Å; I87-W112 HydrophobicContact CG1-CZ3 4.21Å; I87-W112 HydrophobicContact CG2-CH2 3.95Å; I87-W112 HydrophobicContact CG2-CZ3 4.12Å; I110-W112 HydrophobicContact CG2-CE3 4.46Å; W112-V114 PolarHBondContact O-N 3.36Å; W112-F117 HydrophobicContact CB-CB 4.37Å; W112-F117 HydrophobicContact CB-CD2 4.23Å; W112-F117 VanDerWaalsContact CD1-O 3.28Å; W112-F117 HydrophobicContact CG-CB 4.24Å; W112-F117 PolarHBondContact NE1-O 3.27Å; W112-M119 HydrophobicContact CH2-CB 3.65Å; W112-M119 HydrophobicContact CH2-CG 4.07Å; W112-M119 HydrophobicContact CH2-SD 3.8Å; W112-M119 HydrophobicContact CZ2-CB 3.34Å; W112-M119 HydrophobicContact CZ2-CG 4.26Å; W112-M119 HydrophobicContact CZ2-SD 4.39Å; W112-L157 HydrophobicContact CB-CD1 3.97Å; W112-L157 HydrophobicContact CD2-CD2 3.79Å; W112-L157 HydrophobicContact CE3-CD2 4Å; W112-L157 HydrophobicContact CG-CD1 4.26Å; W112-L157 HydrophobicContact CG-CD2 4.05Å
113K98.7Very high98Very high33 Ų3336.4 Ų36.414%0.14317%0.174CC..EExtended strand (participates in β ladder)trans-66.6122.5172.6-74.4-67.3-158.7-169.60110.8D59 L82 Y84 D115 K116 F117D59-K113 PolarHBondContact O-N 3.18Å; L82-K113 PolarHBondContact O-NZ 2.71Å; Y84-K113 HydrophobicContact CD1-CD 4.11Å; Y84-K113 HydrophobicContact CD1-CG 4.2Å; Y84-K113 HydrophobicContact CD2-CD 4.13Å; Y84-K113 HydrophobicContact CE1-CD 3.73Å; Y84-K113 HydrophobicContact CE1-CG 3.71Å; Y84-K113 HydrophobicContact CE2-CD 3.79Å; Y84-K113 HydrophobicContact CG-CD 4.29Å; Y84-K113 WeakPolarHBondContact OH-CE 3.3Å; Y84-K113 PolarHBondContact OH-NZ 3.01Å; K113-D115 VanDerWaalsContact C-N 3.28Å; K113-D115 WeakPolarHBondContact CB-OD1 3.23Å; K113-D115 PolarHBondContact O-N 3.14Å; K113-K116 HydrophobicContact CB-CB 4.39Å; K113-K116 PolarHBondContact O-N 2.99Å; K113-F117 PolarHBondContact O-N 3.39Å
114V98.3Very high98.2Very high62 Ų6236.1 Ų36.138%0.37618%0.175SC..THydrogen-bonded Turntrans-73.1-17.8-172.4-56.90000114.1G83 A85 W112 K160G83-V114 WeakPolarHBondContact O-CG2 3.26Å; G83-V114 PolarHBondContact O-N 3.42Å; A85-V114 HydrophobicContact CB-CG1 3.61Å; W112-V114 PolarHBondContact O-N 3.36Å; V114-K160 WeakPolarHBondContact O-CD 3.17Å; V114-K160 PolarHBondContact O-NZ 3.24Å
115D96.9Very high98.3Very high82 Ų8230.9 Ų30.944%0.43915%0.154SC..THydrogen-bonded Turntrans-78.6-27.3174.463.8-22.1000112K113 K160 S162K113-D115 VanDerWaalsContact C-N 3.28Å; K113-D115 WeakPolarHBondContact CB-OD1 3.23Å; K113-D115 PolarHBondContact O-N 3.14Å; D115-K160 WeakPolarHBondContact O-CB 3.41Å; D115-S162 WeakPolarHBondContact O-CB 3.41Å; D115-S162 PolarHBondContact O-OG 3.12Å
116K97.5Very high98.3Very high25 Ų2532.3 Ų32.311%0.10916%0.161CC..THydrogen-bonded Turntrans-96.5-28.5178.7-70.5-172.2178.3-177.40114.3D59 K113 K160 V163D59-K116 HydrophobicContact CB-CD 4.14Å; D59-K116 VanDerWaalsContact OD1-CD 3.25Å; D59-K116 WeakPolarHBondContact OD1-CD 3.33Å; D59-K116 VanDerWaalsContact OD1-CE 3.28Å; D59-K116 WeakPolarHBondContact OD1-CE 3.29Å; D59-K116 IonicContact OD1-NZ 2.71Å; D59-K116 PolarHBondContact OD1-NZ 3.26Å; D59-K116 IonicContact OD2-NZ 2.79Å; D59-K116 PolarHBondContact OD2-NZ 3.23Å; K113-K116 HydrophobicContact CB-CB 4.39Å; K113-K116 PolarHBondContact O-N 2.99Å; K116-K160 WeakPolarHBondContact O-CB 3.34Å; K116-K160 PolarHBondContact O-N 2.88Å; K116-V163 HydrophobicContact CB-CG1 3.99Å; K116-V163 HydrophobicContact CD-CG1 4.41Å; K116-V163 HydrophobicContact CG-CG1 4.25Å
117F98.6Very high98.3Very high0 Ų032.3 Ų32.30%016%0.161CC..EExtended strand (participates in β ladder)trans-141.6143.8-176.3-51.2-80.3000113.1F14 D59 V60 W112 K113 L157 K158 I159 V163 L185F14-F117 HydrophobicContact CB-CE2 4.4Å; F14-F117 HydrophobicContact CB-CZ 3.89Å; F14-F117 HydrophobicContact CD2-CZ 4.12Å; F14-F117 AromaticContact CG-CZ 3.93Å; F14-F117 HydrophobicContact CG-CZ 3.93Å; D59-F117 HydrophobicContact CB-CE2 4.1Å; V60-F117 HydrophobicContact CG2-CD2 4.34Å; V60-F117 HydrophobicContact CG2-CE2 3.91Å; V60-F117 HydrophobicContact CG2-CZ 4.37Å; W112-F117 HydrophobicContact CB-CB 4.37Å; W112-F117 HydrophobicContact CB-CD2 4.23Å; W112-F117 VanDerWaalsContact CD1-O 3.28Å; W112-F117 HydrophobicContact CG-CB 4.24Å; W112-F117 PolarHBondContact NE1-O 3.27Å; K113-F117 PolarHBondContact O-N 3.39Å; F117-L157 HydrophobicContact CB-CB 4.2Å; F117-L157 HydrophobicContact CB-CD1 4.27Å; F117-L157 HydrophobicContact CD1-CB 4.25Å; F117-L157 HydrophobicContact CD1-CD1 4.5Å; F117-L157 HydrophobicContact CG-CB 4.47Å; F117-L157 HydrophobicContact CG-CD1 4.25Å; F117-K158 WeakPolarHBondContact CA-O 3.33Å; F117-I159 HydrophobicContact CD1-CG1 4.27Å; F117-I159 HydrophobicContact CE1-CG1 4.08Å; F117-V163 HydrophobicContact CE1-CG1 4.16Å; F117-V163 HydrophobicContact CZ-CG1 4.12Å; F117-L185 HydrophobicContact CD1-CD2 4.36Å; F117-L185 HydrophobicContact CE1-CD2 3.73Å; F117-L185 HydrophobicContact CZ-CD2 4.18Å
118D98.3Very high98.1Very high72 Ų7233.3 Ų33.339%0.38517%0.168SC..EExtended strand (participates in β ladder)trans-111.2138.3165.5-64.9-43.1000109.1L157 K158 K160D118-L157 CarbonylContact O-C 3.58Å; D118-L157 WeakPolarHBondContact O-CA 3.25Å; D118-K158 PolarHBondContact N-O 2.84Å; D118-K158 PolarHBondContact O-N 2.64Å; D118-K160 IonicContact OD1-NZ 2.82Å; D118-K160 PolarHBondContact OD1-NZ 2.89Å; D118-K160 WeakPolarHBondContact OD2-CD 3.2Å; D118-K160 WeakPolarHBondContact OD2-CE 3.2Å; D118-K160 IonicContact OD2-NZ 3.42Å; D118-K160 PolarHBondContact OD2-NZ 2.98Å
119M98.4Very high97.9Very high78 Ų7835 Ų3538%0.38418%0.18SC..EExtended strand (participates in β ladder)trans-79.3127.6174.8179.5-160.773.300110.4I87 W112 Q122 L157I87-M119 HydrophobicContact CG2-SD 3.68Å; W112-M119 HydrophobicContact CH2-CB 3.65Å; W112-M119 HydrophobicContact CH2-CG 4.07Å; W112-M119 HydrophobicContact CH2-SD 3.8Å; W112-M119 HydrophobicContact CZ2-CB 3.34Å; W112-M119 HydrophobicContact CZ2-CG 4.26Å; W112-M119 HydrophobicContact CZ2-SD 4.39Å; M119-Q122 HydrophobicContact SD-CB 4.45Å; M119-L157 HydrophobicContact CB-CD2 4.16Å
120D97.8Very high97.8Very high58 Ų5835.6 Ų35.631%0.3118%0.183SC..EExtended strand (participates in β ladder)trans-92.3-48.4174.9-17326.6000111.3V156 K223 Y224D120-V156 HydrophobicContact CB-CB 4.39Å; D120-V156 HydrophobicContact CB-CG1 4.21Å; D120-V156 WeakPolarHBondContact CB-O 3.16Å; D120-V156 PolarHBondContact N-O 2.87Å; D120-K223 IonicContact OD1-NZ 3.67Å; D120-K223 PolarHBondContact OD1-NZ 2.89Å; D120-K223 WeakPolarHBondContact OD2-CE 3.42Å; D120-K223 IonicContact OD2-NZ 2.67Å; D120-K223 PolarHBondContact OD2-NZ 3.08Å; D120-Y224 PolarHBondContact OD2-OH 3.26Å
121K98.4Very high97.5Very high80 Ų8035.6 Ų35.635%0.34818%0.183SC..EExtended strand (participates in β ladder)trans-155.9149.2-178.2-167.5159.4169.9-174.90112.3Y123 V156 E219K121-Y123 HydrophobicContact CB-CE2 4.06Å; K121-Y123 HydrophobicContact CD-CE1 4.28Å; K121-Y123 HydrophobicContact CD-CE2 4.07Å; K121-Y123 VanDerWaalsContact CD-OH 3.31Å; K121-Y123 WeakPolarHBondContact CD-OH 3.36Å; K121-Y123 WeakPolarHBondContact CE-OH 3.46Å; K121-Y123 HydrophobicContact CG-CD2 4.43Å; K121-Y123 HydrophobicContact CG-CE2 3.74Å; K121-V156 PolarHBondContact N-O 3.33Å; K121-V156 PolarHBondContact O-N 3.2Å; K121-E219 IonicContact NZ-OE1 3.52Å; K121-E219 PolarHBondContact NZ-OE1 2.87Å; K121-E219 IonicContact NZ-OE2 2.68Å; K121-E219 PolarHBondContact NZ-OE2 2.99Å
122Q98.5Very high97.2Very high75 Ų7540.6 Ų40.635%0.3521%0.208SC..EExtended strand (participates in β ladder)trans-113.2154170.672.5176.954.700111.8I87 E89 M119 C154I87-Q122 HydrophobicContact CD1-CB 3.67Å; I87-Q122 VanDerWaalsContact CG2-OE1 3.22Å; E89-Q122 PolarHBondContact OE1-NE2 3.14Å; M119-Q122 HydrophobicContact SD-CB 4.45Å; Q122-C154 CarbonylContact C-O 3.53Å; Q122-C154 VanDerWaalsContact CA-O 3.28Å; Q122-C154 WeakPolarHBondContact CA-O 3.35Å
123Y98.7Very high96.9Very high19 Ų1948.4 Ų48.48%0.07524%0.242CC..EExtended strand (participates in β ladder)trans-139.3133.7175.5-57.3-98.5000110.4K121 F125 C154 V156 V216 E219K121-Y123 HydrophobicContact CB-CE2 4.06Å; K121-Y123 HydrophobicContact CD-CE1 4.28Å; K121-Y123 HydrophobicContact CD-CE2 4.07Å; K121-Y123 VanDerWaalsContact CD-OH 3.31Å; K121-Y123 WeakPolarHBondContact CD-OH 3.36Å; K121-Y123 WeakPolarHBondContact CE-OH 3.46Å; K121-Y123 HydrophobicContact CG-CD2 4.43Å; K121-Y123 HydrophobicContact CG-CE2 3.74Å; Y123-F125 HydrophobicContact CG-CE1 4.42Å; Y123-C154 PolarHBondContact N-O 3.34Å; Y123-C154 PolarHBondContact O-N 3.04Å; Y123-V156 HydrophobicContact CD2-CG2 4.48Å; Y123-V156 HydrophobicContact CE2-CG2 3.78Å; Y123-V216 HydrophobicContact CD1-CG2 3.89Å; Y123-V216 HydrophobicContact CD2-CG1 4.15Å; Y123-V216 HydrophobicContact CD2-CG2 3.79Å; Y123-V216 HydrophobicContact CE1-CG2 4.01Å; Y123-V216 HydrophobicContact CE2-CG1 3.76Å; Y123-V216 HydrophobicContact CE2-CG2 3.95Å; Y123-V216 HydrophobicContact CG-CG2 3.75Å; Y123-E219 WeakPolarHBondContact CE1-OE2 3.33Å; Y123-E219 PolarHBondContact OH-OE1 3Å; Y123-E219 PolarHBondContact OH-OE2 2.9Å
124L98.5Very high96.6Very high49 Ų4950 Ų5026%0.25725%0.249SC..EExtended strand (participates in β ladder)trans-99.8127.4169.8174.460.3000109.3E89 E126 I151E89-L124 HydrophobicContact CB-CD1 3.73Å; E89-L124 HydrophobicContact CG-CB 4.25Å; E89-L124 HydrophobicContact CG-CD1 4.01Å; E89-L124 HydrophobicContact CG-CD2 4.39Å; E89-L124 HydrophobicContact CG-CG 4.42Å; L124-E126 HydrophobicContact CD1-CG 4.29Å; L124-E126 HydrophobicContact CD2-CG 3.73Å; L124-E126 HydrophobicContact CG-CG 3.76Å; L124-I151 HydrophobicContact CD1-CB 4.01Å; L124-I151 HydrophobicContact CD1-CD1 4Å; L124-I151 HydrophobicContact CD1-CG2 4.14Å
125F98.2Very high96.2Very high1 Ų147.1 Ų47.10%0.00423%0.231CC..EExtended strand (participates in β ladder)trans-105.691.6175.3-51.7-30.5000109.3Y123 F127 I151 G152 C154 L209 E212 V213 V216Y123-F125 HydrophobicContact CG-CE1 4.42Å; F125-F127 HydrophobicContact CB-CE1 4.3Å; F125-F127 PolarHBondContact O-N 2.8Å; F125-I151 CarbonylContact O-C 3.55Å; F125-I151 WeakPolarHBondContact O-CA 3.1Å; F125-G152 PolarHBondContact N-O 2.9Å; F125-G152 PolarHBondContact O-N 3.47Å; F125-C154 HydrophobicContact CE1-CB 4.29Å; F125-C154 HydrophobicContact CE2-CB 3.57Å; F125-C154 HydrophobicContact CZ-CB 3.43Å; F125-C154 VanDerWaalsContact CZ-CB 3.43Å; F125-L209 HydrophobicContact CD2-CD1 3.82Å; F125-L209 HydrophobicContact CE2-CD1 4.17Å; F125-E212 HydrophobicContact CB-CB 4.48Å; F125-E212 HydrophobicContact CB-CG 4.45Å; F125-E212 HydrophobicContact CD1-CB 3.58Å; F125-E212 HydrophobicContact CD1-CG 3.99Å; F125-E212 HydrophobicContact CD2-CB 3.99Å; F125-E212 HydrophobicContact CE1-CB 3.66Å; F125-E212 HydrophobicContact CE1-CG 4.46Å; F125-E212 HydrophobicContact CE2-CB 4.04Å; F125-E212 HydrophobicContact CG-CB 3.76Å; F125-E212 HydrophobicContact CG-CG 4.19Å; F125-E212 HydrophobicContact CZ-CB 3.87Å; F125-V213 HydrophobicContact CE2-CG2 3.87Å; F125-V213 HydrophobicContact CZ-CG2 4.4Å; F125-V216 HydrophobicContact CE1-CG2 4.04Å; F125-V216 HydrophobicContact CZ-CG2 3.88Å
126E97.4Very high95.8Very high30 Ų3046.1 Ų46.114%0.1423%0.231CC..EExtended strand (participates in β ladder)trans-84102.6173.5-61.3-17894.900109.4S92 K95 L124 S128 S129 V130 I151S92-E126 WeakPolarHBondContact CB-OE1 3.46Å; S92-E126 WeakPolarHBondContact OG-CG 3.36Å; S92-E126 PolarHBondContact OG-OE1 2.8Å; K95-E126 WeakPolarHBondContact CE-OE1 3.42Å; K95-E126 IonicContact NZ-OE1 2.74Å; K95-E126 PolarHBondContact NZ-OE1 3.43Å; K95-E126 IonicContact NZ-OE2 2.73Å; K95-E126 PolarHBondContact NZ-OE2 3.3Å; L124-E126 HydrophobicContact CD1-CG 4.29Å; L124-E126 HydrophobicContact CD2-CG 3.73Å; L124-E126 HydrophobicContact CG-CG 3.76Å; E126-S128 PolarHBondContact O-N 3.03Å; E126-S129 WeakPolarHBondContact O-CA 3.47Å; E126-S129 WeakPolarHBondContact O-CB 3.39Å; E126-S129 PolarHBondContact O-N 3.05Å; E126-V130 WeakPolarHBondContact O-CG2 3.43Å; E126-V130 PolarHBondContact O-N 3.1Å; E126-I151 HydrophobicContact CG-CG2 4.43Å
127F97.3Very high95.4Very high0 Ų050.5 Ų50.50%026%0.26CS..Hα-helixtrans-59.2-35.1-173.6-59-46.3000112.6F125 S129 V130 A131 N150 A190 I192 Q205 M208 L209F125-F127 HydrophobicContact CB-CE1 4.3Å; F125-F127 PolarHBondContact O-N 2.8Å; F127-S129 VanDerWaalsContact C-N 3.34Å; F127-S129 PolarHBondContact O-N 2.86Å; F127-V130 PolarHBondContact O-N 2.78Å; F127-A131 VanDerWaalsContact O-CB 3.31Å; F127-A131 WeakPolarHBondContact O-CB 3.36Å; F127-A131 PolarHBondContact O-N 3.23Å; F127-N150 HydrophobicContact CD2-CB 3.87Å; F127-N150 VanDerWaalsContact CD2-O 3.28Å; F127-N150 WeakPolarHBondContact CD2-O 3.25Å; F127-N150 HydrophobicContact CE2-CB 4.27Å; F127-A190 HydrophobicContact CZ-CB 4.38Å; F127-I192 HydrophobicContact CE2-CD1 3.87Å; F127-I192 HydrophobicContact CZ-CD1 4.1Å; F127-Q205 HydrophobicContact CB-CG 4.11Å; F127-Q205 HydrophobicContact CD2-CB 3.99Å; F127-Q205 HydrophobicContact CD2-CG 3.85Å; F127-Q205 HydrophobicContact CE2-CB 4.23Å; F127-Q205 HydrophobicContact CG-CB 4.27Å; F127-Q205 HydrophobicContact CG-CG 4.07Å; F127-M208 HydrophobicContact CB-SD 4.06Å; F127-M208 HydrophobicContact CD1-CB 3.81Å; F127-M208 HydrophobicContact CE1-CB 4.3Å; F127-L209 HydrophobicContact CE1-CB 4.03Å; F127-L209 HydrophobicContact CZ-CB 4.19Å
128S94.8Very high95.2Very high22 Ų2250.8 Ų50.815%0.15426%0.262CS..Hα-helixtrans-60.1-41172.458.10000112.8E126 M132 M146E126-S128 PolarHBondContact O-N 3.03Å; S128-M132 WeakPolarHBondContact O-CB 3.46Å; S128-M132 PolarHBondContact O-N 3.02Å; S128-M146 WeakPolarHBondContact CB-O 3.42Å
129S94.8Very high95.1Very high36 Ų3654.4 Ų54.425%0.25228%0.277SS..Hα-helixtrans-71.7-35.9175.9-66.70000112.3E126 F127 M132 K133E126-S129 WeakPolarHBondContact O-CA 3.47Å; E126-S129 WeakPolarHBondContact O-CB 3.39Å; E126-S129 PolarHBondContact O-N 3.05Å; F127-S129 VanDerWaalsContact C-N 3.34Å; F127-S129 PolarHBondContact O-N 2.86Å; S129-M132 PolarHBondContact O-N 2.88Å; S129-K133 WeakPolarHBondContact O-CB 3.31Å; S129-K133 VanDerWaalsContact O-CG 3.3Å; S129-K133 WeakPolarHBondContact O-CG 3.46Å; S129-K133 PolarHBondContact O-N 3.41Å
130V95.2Very high94.8Very high11 Ų1152.4 Ų52.47%0.06727%0.268CS..Hα-helixtrans-64.5-46.9173.9-179.60000110.1E126 F127 M132 K133 K134 M208 E212 F275E126-V130 WeakPolarHBondContact O-CG2 3.43Å; E126-V130 PolarHBondContact O-N 3.1Å; F127-V130 PolarHBondContact O-N 2.78Å; V130-M132 VanDerWaalsContact C-N 3.35Å; V130-M132 PolarHBondContact O-N 3.2Å; V130-K133 PolarHBondContact O-N 3.04Å; V130-K134 HydrophobicContact CG1-CD 4.19Å; V130-K134 WeakPolarHBondContact O-CB 3.42Å; V130-K134 PolarHBondContact O-N 3.27Å; V130-M208 HydrophobicContact CB-CG 4.42Å; V130-M208 HydrophobicContact CB-SD 4.16Å; V130-M208 HydrophobicContact CG1-CB 4.13Å; V130-M208 HydrophobicContact CG1-CG 3.87Å; V130-M208 HydrophobicContact CG1-SD 4.17Å; V130-E212 HydrophobicContact CG2-CG 3.99Å; V130-F275 HydrophobicContact CG1-CE1 3.83Å; V130-F275 HydrophobicContact CG1-CZ 4.43Å
131A94.3Very high94.7Very high0 Ų049.7 Ų49.70%025%0.253CS..Hα-helixtrans-57.6-45.9175.100000111.6F127 A135 S136 M141 V145 M146 M208F127-A131 VanDerWaalsContact O-CB 3.31Å; F127-A131 WeakPolarHBondContact O-CB 3.36Å; F127-A131 PolarHBondContact O-N 3.23Å; A131-A135 CarbonylContact O-C 3.59Å; A131-A135 VanDerWaalsContact O-C 3.28Å; A131-A135 VanDerWaalsContact O-CA 3.29Å; A131-A135 WeakPolarHBondContact O-CA 3.45Å; A131-A135 PolarHBondContact O-N 3.36Å; A131-S136 PolarHBondContact O-N 3.32Å; A131-M141 HydrophobicContact CB-SD 3.93Å; A131-V145 HydrophobicContact CB-CG1 4.23Å; A131-M146 HydrophobicContact CB-CG 3.55Å; A131-M146 HydrophobicContact CB-SD 4.42Å; A131-M208 HydrophobicContact CB-CE 3.58Å; A131-M208 HydrophobicContact CB-SD 4.36Å
132M92.3Very high94.5Very high107 Ų10749.2 Ų49.253%0.52725%0.254SS..Hα-helixtrans-62.7-46.4177.5-173.8-175.2-69.900112.5S128 S129 V130 S136 M146S128-M132 WeakPolarHBondContact O-CB 3.46Å; S128-M132 PolarHBondContact O-N 3.02Å; S129-M132 PolarHBondContact O-N 2.88Å; V130-M132 VanDerWaalsContact C-N 3.35Å; V130-M132 PolarHBondContact O-N 3.2Å; M132-S136 VanDerWaalsContact O-CB 3.23Å; M132-S136 WeakPolarHBondContact O-CB 3.32Å; M132-S136 PolarHBondContact O-OG 3.38Å; M132-M146 HydrophobicContact CB-CE 3.79Å; M132-M146 HydrophobicContact CB-SD 3.99Å; M132-M146 HydrophobicContact CE-CE 3.49Å; M132-M146 VanDerWaalsContact CE-CE 3.49Å; M132-M146 HydrophobicContact CG-CE 4Å
133K93.2Very high94.3Very high176 Ų17651 Ų5177%0.76527%0.266SS*.Hα-helixtrans-69.6-40.2-177.2-73.7172.9-175.8174.50112.6S129 V130S129-K133 WeakPolarHBondContact O-CB 3.31Å; S129-K133 VanDerWaalsContact O-CG 3.3Å; S129-K133 WeakPolarHBondContact O-CG 3.46Å; S129-K133 PolarHBondContact O-N 3.41Å; V130-K133 PolarHBondContact O-N 3.04Å
134K91.2Very high94.1Very high68 Ų6853 Ų5330%0.29627%0.273SS..Hα-helixtrans-95.1-35.5-172.9-75.7177171.1-91.70112.1V130 H211 K274 F275V130-K134 HydrophobicContact CG1-CD 4.19Å; V130-K134 WeakPolarHBondContact O-CB 3.42Å; V130-K134 PolarHBondContact O-N 3.27Å; K134-H211 WeakPolarHBondContact CE-NE2 3.38Å; K134-H211 PolarHBondContact NZ-CE1 3.13Å; K134-H211 PolarHBondContact NZ-NE2 2.85Å; K134-K274 HydrophobicContact CB-CD 4.42Å; K134-K274 WeakPolarHBondContact O-CD 3.4Å; K134-K274 VanDerWaalsContact O-CE 3.24Å; K134-K274 WeakPolarHBondContact O-CE 3.24Å; K134-K274 PolarHBondContact O-NZ 2.92Å; K134-F275 HydrophobicContact CB-CE1 4.12Å; K134-F275 HydrophobicContact CB-CZ 3.93Å; K134-F275 HydrophobicContact CD-CD1 4.29Å; K134-F275 HydrophobicContact CD-CE1 3.62Å; K134-F275 HydrophobicContact CD-CZ 4.31Å; K134-F275 HydrophobicContact CG-CE1 4.49Å
135A90.1Very high94Very high0 Ų050.6 Ų50.60%026%0.261CS..Hα-helixtrans-135.330-164.200000114.4A131 T137 S138 M141 C271A131-A135 CarbonylContact O-C 3.59Å; A131-A135 VanDerWaalsContact O-C 3.28Å; A131-A135 VanDerWaalsContact O-CA 3.29Å; A131-A135 WeakPolarHBondContact O-CA 3.45Å; A131-A135 PolarHBondContact O-N 3.36Å; A135-T137 PolarHBondContact O-N 3.13Å; A135-S138 PolarHBondContact O-N 3.41Å; A135-M141 HydrophobicContact CB-CB 4.26Å; A135-M141 HydrophobicContact CB-CG 3.56Å; A135-M141 HydrophobicContact CB-SD 4.03Å; A135-M141 WeakPolarHBondContact O-CB 3.44Å; A135-C271 HydrophobicContact CB-CB 3.72Å
136S87.8Confident93.8Very high61 Ų6152.4 Ų52.443%0.42727%0.27SS..THydrogen-bonded Turntrans-57.8-17.1177.949.50000115.6A131 M132 L142A131-S136 PolarHBondContact O-N 3.32Å; M132-S136 VanDerWaalsContact O-CB 3.23Å; M132-S136 WeakPolarHBondContact O-CB 3.32Å; M132-S136 PolarHBondContact O-OG 3.38Å; S136-L142 WeakPolarHBondContact O-CD1 3.29Å
137T90.6Very high93.7Very high118 Ų11854.9 Ų54.972%0.72429%0.288SS*.THydrogen-bonded Turntrans-87-7.9178.4600000113.7A135A135-T137 PolarHBondContact O-N 3.13Å
138S94.5Very high93.6Very high6 Ų657.2 Ų57.24%0.04230%0.297CS..  trans-91124178.7157.60000110.4A135 N140 M141 L142 D269A135-S138 PolarHBondContact O-N 3.41Å; S138-N140 VanDerWaalsContact C-N 3.29Å; S138-N140 PolarHBondContact O-N 3.44Å; S138-N140 PolarHBondContact OG-N 3.44Å; S138-M141 WeakPolarHBondContact O-CB 3.41Å; S138-M141 PolarHBondContact O-N 3.33Å; S138-M141 PolarHBondContact OG-N 2.91Å; S138-L142 VanDerWaalsContact O-CG 3.32Å; S138-L142 WeakPolarHBondContact O-CG 3.28Å; S138-L142 PolarHBondContact O-N 2.75Å; S138-D269 WeakPolarHBondContact CB-OD2 3.39Å; S138-D269 PolarHBondContact OG-OD2 3.2Å
139E94.4Very high93.6Very high148 Ų14858 Ų5869%0.69230%0.3SS*.Hα-helixtrans-62.1-38.5174-65.8-174.5175.400111.7M141 L142 N143E139-M141 VanDerWaalsContact C-N 3.33Å; E139-M141 PolarHBondContact O-N 2.81Å; E139-L142 PolarHBondContact O-N 2.64Å; E139-N143 VanDerWaalsContact O-CB 3.29Å; E139-N143 WeakPolarHBondContact O-CB 3.19Å; E139-N143 VanDerWaalsContact O-CG 3.29Å; E139-N143 PolarHBondContact O-N 2.73Å; E139-N143 PolarHBondContact O-ND2 3.18Å
140N93.9Very high93.8Very high36 Ų3656.6 Ų56.619%0.19329%0.289CS..Hα-helixtrans-61.8-42.2176.7-66-55.5000111.1S138 R144 S265 F266 D269S138-N140 VanDerWaalsContact C-N 3.29Å; S138-N140 PolarHBondContact O-N 3.44Å; S138-N140 PolarHBondContact OG-N 3.44Å; N140-R144 VanDerWaalsContact O-CB 3.23Å; N140-R144 WeakPolarHBondContact O-CB 3.39Å; N140-R144 PolarHBondContact O-N 2.92Å; N140-S265 PolarHBondContact ND2-O 3.49Å; N140-S265 WeakPolarHBondContact OD1-CB 3.16Å; N140-S265 PolarHBondContact OD1-OG 2.73Å; N140-F266 HydrophobicContact CB-CD1 3.75Å; N140-F266 HydrophobicContact CB-CD2 4.37Å; N140-F266 HydrophobicContact CB-CE1 3.19Å; N140-F266 HydrophobicContact CB-CE2 3.95Å; N140-F266 HydrophobicContact CB-CG 4.3Å; N140-F266 HydrophobicContact CB-CZ 3.34Å; N140-D269 PolarHBondContact ND2-OD2 3.03Å
141M94.8Very high93.9Very high0 Ų056.1 Ų56.10%029%0.286CS..Iπ-helixtrans-62.2-48.4175.1-77.7-77.1104.700112.6A131 A135 S138 E139 N143 V145 M146 V204 M208 F266 C271A131-M141 HydrophobicContact CB-SD 3.93Å; A135-M141 HydrophobicContact CB-CB 4.26Å; A135-M141 HydrophobicContact CB-CG 3.56Å; A135-M141 HydrophobicContact CB-SD 4.03Å; A135-M141 WeakPolarHBondContact O-CB 3.44Å; S138-M141 WeakPolarHBondContact O-CB 3.41Å; S138-M141 PolarHBondContact O-N 3.33Å; S138-M141 PolarHBondContact OG-N 2.91Å; E139-M141 VanDerWaalsContact C-N 3.33Å; E139-M141 PolarHBondContact O-N 2.81Å; M141-N143 PolarHBondContact O-N 3.46Å; M141-V145 HydrophobicContact CE-CB 3.68Å; M141-V145 HydrophobicContact CE-CG1 4.14Å; M141-V145 HydrophobicContact CE-CG2 3.32Å; M141-V145 PolarHBondContact O-N 3.42Å; M141-V145 HydrophobicContact SD-CB 4.2Å; M141-V145 HydrophobicContact SD-CG1 4.39Å; M141-V145 HydrophobicContact SD-CG2 4.46Å; M141-M146 WeakPolarHBondContact O-CB 3.49Å; M141-M146 WeakPolarHBondContact O-CG 3.48Å; M141-M146 PolarHBondContact O-N 3.02Å; M141-V204 HydrophobicContact CE-CB 4.08Å; M141-V204 HydrophobicContact CE-CG1 3.37Å; M141-V204 HydrophobicContact CE-CG2 4.25Å; M141-V204 HydrophobicContact SD-CG1 4.25Å; M141-M208 HydrophobicContact CE-CE 4.24Å; M141-M208 HydrophobicContact SD-CE 3.53Å; M141-M208 VanDerWaalsContact SD-CE 3.53Å; M141-F266 HydrophobicContact CE-CD1 4.08Å; M141-F266 HydrophobicContact CE-CE1 3.08Å; M141-F266 HydrophobicContact CE-CE2 4.38Å; M141-F266 HydrophobicContact CE-CZ 3.25Å; M141-F266 HydrophobicContact CG-CE1 4.06Å; M141-F266 HydrophobicContact SD-CE1 4.42Å; M141-C271 HydrophobicContact CG-CB 4.5Å
142L93.6Very high94.1Very high71 Ų7156.1 Ų56.137%0.37229%0.286SS..Iπ-helixtrans-63.1-41.8-178.5-68.4168.1000112.1S136 S138 E139 M146 P147S136-L142 WeakPolarHBondContact O-CD1 3.29Å; S138-L142 VanDerWaalsContact O-CG 3.32Å; S138-L142 WeakPolarHBondContact O-CG 3.28Å; S138-L142 PolarHBondContact O-N 2.75Å; E139-L142 PolarHBondContact O-N 2.64Å; L142-M146 HydrophobicContact CD2-CE 4.14Å; L142-M146 HydrophobicContact CD2-SD 3.6Å; L142-M146 HydrophobicContact CG-SD 4.49Å; L142-P147 VanDerWaalsContact O-CD 3.31Å; L142-P147 WeakPolarHBondContact O-CD 3.39Å; L142-P147 WeakPolarHBondContact O-CG 3.47Å
143N94.6Very high94.4Very high112 Ų11251 Ų5160%0.59926%0.261SS*.Iπ-helixtrans-90.7-31.7-170.9-65.2-27.8000113.3E139 M141E139-N143 VanDerWaalsContact O-CB 3.29Å; E139-N143 WeakPolarHBondContact O-CB 3.19Å; E139-N143 VanDerWaalsContact O-CG 3.29Å; E139-N143 PolarHBondContact O-N 2.73Å; E139-N143 PolarHBondContact O-ND2 3.18Å; M141-N143 PolarHBondContact O-N 3.46Å
144R95.8Very high94.7Very high60 Ų6042.6 Ų42.623%0.22623%0.225CC..Iπ-helixtrans-107.8-39.4-170.4-53.7-177.758.372.24.7113N140 F198 D200 V201N140-R144 VanDerWaalsContact O-CB 3.23Å; N140-R144 WeakPolarHBondContact O-CB 3.39Å; N140-R144 PolarHBondContact O-N 2.92Å; R144-F198 VanDerWaalsContact NH2-CD1 3.31Å; R144-D200 IonicContact CZ-OD1 3.79Å; R144-D200 IonicContact CZ-OD2 3.29Å; R144-D200 VanDerWaalsContact CZ-OD2 3.29Å; R144-D200 IonicContact NE-OD1 3.9Å; R144-D200 IonicContact NE-OD2 2.66Å; R144-D200 PolarHBondContact NE-OD2 3.19Å; R144-D200 VanDerWaalsContact NH2-CG 3.35Å; R144-D200 IonicContact NH2-OD1 2.83Å; R144-D200 PolarHBondContact NH2-OD1 2.69Å; R144-D200 IonicContact NH2-OD2 3.08Å; R144-D200 PolarHBondContact NH2-OD2 2.94Å; R144-D200 VanDerWaalsContact NH2-OD2 3.08Å; R144-V201 HydrophobicContact CB-CG2 4.03Å; R144-V201 WeakPolarHBondContact O-CG2 3.44Å
145V95.2Very high95.1Very high0 Ų039.4 Ų39.40%021%0.211CC..Iπ-helixtrans-100.2-48-173.5178.70000112.9A131 M141 P147 R148 V201 V204 Q205 M208 F266A131-V145 HydrophobicContact CB-CG1 4.23Å; M141-V145 HydrophobicContact CE-CB 3.68Å; M141-V145 HydrophobicContact CE-CG1 4.14Å; M141-V145 HydrophobicContact CE-CG2 3.32Å; M141-V145 PolarHBondContact O-N 3.42Å; M141-V145 HydrophobicContact SD-CB 4.2Å; M141-V145 HydrophobicContact SD-CG1 4.39Å; M141-V145 HydrophobicContact SD-CG2 4.46Å; V145-P147 VanDerWaalsContact C-CD 3.42Å; V145-R148 WeakPolarHBondContact O-CB 3.26Å; V145-R148 PolarHBondContact O-N 3.5Å; V145-R148 VanDerWaalsContact O-N 3.07Å; V145-V201 HydrophobicContact CG2-CB 4.28Å; V145-V201 HydrophobicContact CG2-CG1 4.13Å; V145-V201 HydrophobicContact CG2-CG2 3.94Å; V145-V204 HydrophobicContact CG2-CB 4.47Å; V145-Q205 HydrophobicContact CG1-CG 4.47Å; V145-M208 HydrophobicContact CG1-CE 4.11Å; V145-M208 HydrophobicContact CG1-SD 4.38Å; V145-F266 HydrophobicContact CG2-CE2 4.43Å; V145-F266 HydrophobicContact CG2-CZ 3.93Å
146M93.6Very high95.5Very high38 Ų3839.4 Ų39.419%0.18721%0.211CC..THydrogen-bonded Turntrans-57.8-34.6-178.2-80.4-173.25200115.6S128 A131 M132 M141 L142 R148S128-M146 WeakPolarHBondContact CB-O 3.42Å; A131-M146 HydrophobicContact CB-CG 3.55Å; A131-M146 HydrophobicContact CB-SD 4.42Å; M132-M146 HydrophobicContact CB-CE 3.79Å; M132-M146 HydrophobicContact CB-SD 3.99Å; M132-M146 HydrophobicContact CE-CE 3.49Å; M132-M146 VanDerWaalsContact CE-CE 3.49Å; M132-M146 HydrophobicContact CG-CE 4Å; M141-M146 WeakPolarHBondContact O-CB 3.49Å; M141-M146 WeakPolarHBondContact O-CG 3.48Å; M141-M146 PolarHBondContact O-N 3.02Å; L142-M146 HydrophobicContact CD2-CE 4.14Å; L142-M146 HydrophobicContact CD2-SD 3.6Å; L142-M146 HydrophobicContact CG-SD 4.49Å; M146-R148 PolarHBondContact O-N 2.97Å
147P95.2Very high96Very high82 Ų8236.5 Ų36.553%0.53219%0.191SC..THydrogen-bonded Turntrans-74-4.9178.5-1833.4000113.8L142 V145L142-P147 VanDerWaalsContact O-CD 3.31Å; L142-P147 WeakPolarHBondContact O-CD 3.39Å; L142-P147 WeakPolarHBondContact O-CG 3.47Å; V145-P147 VanDerWaalsContact C-CD 3.42Å
148R95.6Very high96.4Very high50 Ų5035.5 Ų35.519%0.18918%0.176CC..  trans-92.6134.3177.6-52.7-57.5-174.3-91.23109.6V145 M146 H193 V201V145-R148 WeakPolarHBondContact O-CB 3.26Å; V145-R148 PolarHBondContact O-N 3.5Å; V145-R148 VanDerWaalsContact O-N 3.07Å; M146-R148 PolarHBondContact O-N 2.97Å; R148-H193 VanDerWaalsContact CD-CE1 3.5Å; R148-H193 WeakPolarHBondContact CD-CE1 3.45Å; R148-H193 PolarHBondContact NE-CE1 2.74Å; R148-H193 VanDerWaalsContact NE-CE1 3.31Å; R148-H193 PolarHBondContact NE-NE2 2.95Å; R148-H193 VanDerWaalsContact NE-NE2 3.11Å; R148-V201 HydrophobicContact CG-CG1 4.13Å
149D94.9Very high96.6Very high38 Ų3835.3 Ų35.320%0.20318%0.175CC..  trans-10215.9-172.369.1-20.1000113.6K91 S92 R93K91-D149 WeakPolarHBondContact CB-O 3.23Å; S92-D149 PolarHBondContact N-O 3.47Å; R93-D149 HydrophobicContact CB-CB 4.47Å; R93-D149 WeakPolarHBondContact CB-OD2 3.41Å; R93-D149 WeakPolarHBondContact CD-OD2 3.39Å; R93-D149 WeakPolarHBondContact CG-OD2 3.46Å; R93-D149 IonicContact CZ-OD2 3.97Å; R93-D149 IonicContact NE-OD2 3.44Å; R93-D149 IonicContact NH1-OD1 3.66Å; R93-D149 IonicContact NH1-OD2 3.57Å; R93-D149 PolarHBondContact NH1-OD2 2.67Å
150N98.2Very high96.6Very high6 Ų631.1 Ų31.13%0.03215%0.154CC..  trans-58.2148.1174.4-61.597.2000111.3F127 H191 H193 Q205F127-N150 HydrophobicContact CD2-CB 3.87Å; F127-N150 VanDerWaalsContact CD2-O 3.28Å; F127-N150 WeakPolarHBondContact CD2-O 3.25Å; F127-N150 HydrophobicContact CE2-CB 4.27Å; N150-H191 WeakPolarHBondContact CB-O 3.44Å; N150-H191 PolarHBondContact ND2-O 3.37Å; N150-H193 PolarHBondContact ND2-N 3.34Å; N150-H193 WeakPolarHBondContact OD1-CB 3.46Å; N150-Q205 PolarHBondContact OD1-NE2 2.85Å
151I98.5Very high96.5Very high1 Ų136.3 Ų36.31%0.00518%0.177CC..EExtended strand (participates in β ladder)trans-133.5158.9-176.861.5161.4000111.6E89 L124 F125 E126 H191E89-I151 HydrophobicContact CB-CD1 4.06Å; E89-I151 WeakPolarHBondContact O-CD1 3.49Å; L124-I151 HydrophobicContact CD1-CB 4.01Å; L124-I151 HydrophobicContact CD1-CD1 4Å; L124-I151 HydrophobicContact CD1-CG2 4.14Å; F125-I151 CarbonylContact O-C 3.55Å; F125-I151 WeakPolarHBondContact O-CA 3.1Å; E126-I151 HydrophobicContact CG-CG2 4.43Å; I151-H191 PolarHBondContact O-N 3.38Å
152G98.7Very high96.4Very high0 Ų039 Ų390%020%0.196CC..EExtended strand (participates in β ladder)trans-114.3149.4156.400000110.8F125 T189F125-G152 PolarHBondContact N-O 2.9Å; F125-G152 PolarHBondContact O-N 3.47Å; G152-T189 CarbonylContact C-O 3.58Å; G152-T189 VanDerWaalsContact CA-O 3.25Å; G152-T189 WeakPolarHBondContact CA-O 3.49Å
153L98.8Very high96.3Very high0 Ų035.6 Ų35.60%018%0.178CC..EExtended strand (participates in β ladder)trans-122.6136.2173.9178.857.9000108.5I87 E89 C108 I110 A188 T189I87-L153 HydrophobicContact CD1-CD1 3.92Å; I87-L153 HydrophobicContact CD1-CD2 4.22Å; I87-L153 HydrophobicContact CD1-CG 4.09Å; I87-L153 HydrophobicContact CG1-CD2 4.06Å; I87-L153 HydrophobicContact CG1-CG 4.47Å; E89-L153 HydrophobicContact CB-CD1 4.28Å; E89-L153 HydrophobicContact CG-CD1 3.7Å; C108-L153 HydrophobicContact CB-CB 4.2Å; C108-L153 VanDerWaalsContact O-CD2 3.23Å; C108-L153 WeakPolarHBondContact O-CD2 3.28Å; I110-L153 HydrophobicContact CD1-CG 4.1Å; I110-L153 HydrophobicContact CG1-CD2 4.22Å; I110-L153 HydrophobicContact CG1-CG 4.3Å; L153-A188 CarbonylContact O-C 3.47Å; L153-A188 VanDerWaalsContact O-CA 3.29Å; L153-A188 WeakPolarHBondContact O-CA 3.36Å; L153-T189 HydrophobicContact CB-CG2 4.04Å; L153-T189 PolarHBondContact N-O 2.93Å; L153-T189 PolarHBondContact O-N 3.26Å
154C98.9Very high96.1Very high0 Ų031.4 Ų31.40%015%0.154CC..EExtended strand (participates in β ladder)trans-133.8135.9-178.6175.10000111.1Q122 Y123 F125 V187 A188Q122-C154 CarbonylContact C-O 3.53Å; Q122-C154 VanDerWaalsContact CA-O 3.28Å; Q122-C154 WeakPolarHBondContact CA-O 3.35Å; Y123-C154 PolarHBondContact N-O 3.34Å; Y123-C154 PolarHBondContact O-N 3.04Å; F125-C154 HydrophobicContact CE1-CB 4.29Å; F125-C154 HydrophobicContact CE2-CB 3.57Å; F125-C154 HydrophobicContact CZ-CB 3.43Å; F125-C154 VanDerWaalsContact CZ-CB 3.43Å; C154-V187 CarbonylContact C-O 3.41Å; C154-V187 WeakPolarHBondContact CA-O 3.15Å; C154-A188 HydrophobicContact CB-CB 4.2Å
155A98.9Very high94.8Very high0 Ų031.4 Ų31.40%017%0.167CC..EExtended strand (participates in β ladder)trans-118.6134.5173.700000110I87 I110 L157 V187I87-A155 HydrophobicContact CD1-CB 3.95Å; I110-A155 HydrophobicContact CD1-CB 4.12Å; I110-A155 HydrophobicContact CG2-CB 4.44Å; A155-L157 HydrophobicContact CB-CD2 4.06Å; A155-L157 HydrophobicContact CB-CG 4.35Å; A155-V187 PolarHBondContact N-O 3.2Å; A155-V187 PolarHBondContact O-N 3.01Å
156V98.9Very high93Very high1 Ų137.8 Ų37.81%0.00620%0.201CC..EExtended strand (participates in β ladder)trans-96.1111.9164.3-1770000106.8D120 K121 Y123 P184 V186 V216 V220D120-V156 HydrophobicContact CB-CB 4.39Å; D120-V156 HydrophobicContact CB-CG1 4.21Å; D120-V156 WeakPolarHBondContact CB-O 3.16Å; D120-V156 PolarHBondContact N-O 2.87Å; K121-V156 PolarHBondContact N-O 3.33Å; K121-V156 PolarHBondContact O-N 3.2Å; Y123-V156 HydrophobicContact CD2-CG2 4.48Å; Y123-V156 HydrophobicContact CE2-CG2 3.78Å; V156-P184 HydrophobicContact CG1-CB 4.22Å; V156-V186 HydrophobicContact CG2-CG2 4.33Å; V156-V216 HydrophobicContact CG2-CG1 3.87Å; V156-V220 HydrophobicContact CB-CG2 4.47Å; V156-V220 HydrophobicContact CG1-CG2 3.91Å; V156-V220 HydrophobicContact CG2-CG2 3.68Å
157L98.9Very high90.9Very high0 Ų046.2 Ų46.20%024%0.237CC..EExtended strand (participates in β ladder)trans-102.5136.3179.7-58.6-176.3000109.6V60 W112 F117 D118 M119 A155 P184 L185 V187V60-L157 HydrophobicContact CG2-CD1 4.29Å; W112-L157 HydrophobicContact CB-CD1 3.97Å; W112-L157 HydrophobicContact CD2-CD2 3.79Å; W112-L157 HydrophobicContact CE3-CD2 4Å; W112-L157 HydrophobicContact CG-CD1 4.26Å; W112-L157 HydrophobicContact CG-CD2 4.05Å; F117-L157 HydrophobicContact CB-CB 4.2Å; F117-L157 HydrophobicContact CB-CD1 4.27Å; F117-L157 HydrophobicContact CD1-CB 4.25Å; F117-L157 HydrophobicContact CD1-CD1 4.5Å; F117-L157 HydrophobicContact CG-CB 4.47Å; F117-L157 HydrophobicContact CG-CD1 4.25Å; D118-L157 CarbonylContact O-C 3.58Å; D118-L157 WeakPolarHBondContact O-CA 3.25Å; M119-L157 HydrophobicContact CB-CD2 4.16Å; A155-L157 HydrophobicContact CB-CD2 4.06Å; A155-L157 HydrophobicContact CB-CG 4.35Å; L157-P184 CarbonylContact O-C 3.49Å; L157-P184 WeakPolarHBondContact O-CA 3.43Å; L157-L185 HydrophobicContact CB-CB 4.4Å; L157-L185 PolarHBondContact N-O 2.78Å; L157-L185 PolarHBondContact O-N 2.89Å; L157-V187 HydrophobicContact CD1-CG2 3.91Å; L157-V187 HydrophobicContact CG-CG2 4.47Å
158K98.5Very high88.8Confident96 Ų9649.9 Ų49.942%0.41725%0.245SC..EExtended strand (participates in β ladder)trans-94.3125.1171.5-174.6178.7-179.3-178.70109F117 D118F117-K158 WeakPolarHBondContact CA-O 3.33Å; D118-K158 PolarHBondContact N-O 2.84Å; D118-K158 PolarHBondContact O-N 2.64Å
159I98Very high86.5Confident3 Ų353.8 Ų53.82%0.01527%0.268CS..EExtended strand (participates in β ladder)trans-72.6136.1-177.1-62.7158000110.8F117 V163 V180 G182 N183 L185 I362F117-I159 HydrophobicContact CD1-CG1 4.27Å; F117-I159 HydrophobicContact CE1-CG1 4.08Å; I159-V163 HydrophobicContact CG2-CB 4.32Å; I159-V163 HydrophobicContact CG2-CG1 3.77Å; I159-V163 HydrophobicContact CG2-CG2 3.64Å; I159-V180 HydrophobicContact CD1-CG2 4.47Å; I159-V180 HydrophobicContact CG2-CG2 3.95Å; I159-G182 PolarHBondContact O-N 2.97Å; I159-N183 HydrophobicContact CD1-CB 4.16Å; I159-N183 WeakPolarHBondContact CG1-O 3.4Å; I159-N183 PolarHBondContact N-O 3.28Å; I159-L185 HydrophobicContact CD1-CB 4.41Å; I159-L185 HydrophobicContact CG1-CB 4.31Å; I159-I362 HydrophobicContact CD1-CD1 3.86Å; I159-I362 HydrophobicContact CD1-CG2 4.37Å; I159-I362 HydrophobicContact CG1-CD1 4.31Å; I159-I362 HydrophobicContact CG2-CD1 4.42Å
160K95.9Very high84.4Confident59 Ų5956.4 Ų56.426%0.25730%0.304SS..  trans-110166.1176.7-56.5172.380156.40110.7V114 D115 K116 D118 S162 V163V114-K160 WeakPolarHBondContact O-CD 3.17Å; V114-K160 PolarHBondContact O-NZ 3.24Å; D115-K160 WeakPolarHBondContact O-CB 3.41Å; K116-K160 WeakPolarHBondContact O-CB 3.34Å; K116-K160 PolarHBondContact O-N 2.88Å; D118-K160 IonicContact OD1-NZ 2.82Å; D118-K160 PolarHBondContact OD1-NZ 2.89Å; D118-K160 WeakPolarHBondContact OD2-CD 3.2Å; D118-K160 WeakPolarHBondContact OD2-CE 3.2Å; D118-K160 IonicContact OD2-NZ 3.42Å; D118-K160 PolarHBondContact OD2-NZ 2.98Å; K160-S162 PolarHBondContact O-N 3.42Å; K160-S162 VanDerWaalsContact O-N 3.15Å; K160-V163 VanDerWaalsContact O-CG2 3.3Å; K160-V163 WeakPolarHBondContact O-CG2 3.38Å; K160-V163 PolarHBondContact O-N 3.24Å
161E91.9Very high82.3Confident145 Ų14567.2 Ų67.268%0.67835%0.345SS*.G310 helixtrans-57.5-30.5-176.4-170.1172-164.500114.1V163 Y164 V181E161-V163 PolarHBondContact O-N 3.1Å; E161-Y164 WeakPolarHBondContact O-CD2 3.38Å; E161-Y164 PolarHBondContact O-N 3.02Å; E161-Y164 VanDerWaalsContact O-N 3.07Å; E161-V181 HydrophobicContact CB-CG2 4.13Å
162S91.4Very high80.4Confident56 Ų5671.8 Ų71.839%0.39237%0.368SS..G310 helixtrans-64.4-7.5-176.6-45.10000114.8D115 K160 Y164D115-S162 WeakPolarHBondContact O-CB 3.41Å; D115-S162 PolarHBondContact O-OG 3.12Å; K160-S162 PolarHBondContact O-N 3.42Å; K160-S162 VanDerWaalsContact O-N 3.15Å; S162-Y164 PolarHBondContact O-N 2.89Å
163V92.6Very high79Confident0 Ų080.6 Ų80.60%041%0.408CS..G310 helixtrans-68.7-20.4171.2-60.50000113.1A12 T13 K116 F117 I159 K160 E161 A165 V180A12-V163 WeakPolarHBondContact CA-O 3.25Å; A12-V163 HydrophobicContact CB-CB 4.3Å; A12-V163 HydrophobicContact CB-CG2 3.61Å; T13-V163 PolarHBondContact N-O 3.18Å; K116-V163 HydrophobicContact CB-CG1 3.99Å; K116-V163 HydrophobicContact CD-CG1 4.41Å; K116-V163 HydrophobicContact CG-CG1 4.25Å; F117-V163 HydrophobicContact CE1-CG1 4.16Å; F117-V163 HydrophobicContact CZ-CG1 4.12Å; I159-V163 HydrophobicContact CG2-CB 4.32Å; I159-V163 HydrophobicContact CG2-CG1 3.77Å; I159-V163 HydrophobicContact CG2-CG2 3.64Å; K160-V163 VanDerWaalsContact O-CG2 3.3Å; K160-V163 WeakPolarHBondContact O-CG2 3.38Å; K160-V163 PolarHBondContact O-N 3.24Å; E161-V163 PolarHBondContact O-N 3.1Å; V163-A165 PolarHBondContact O-N 3.14Å; V163-V180 HydrophobicContact CG2-CG2 4.22Å
164Y89.4Confident78Confident24 Ų2482.2 Ų82.29%0.09442%0.417CS..SBendtrans-82.847.6178.5-70-77.7000112.2P10 A12 E161 S162 N166 I174 D178 N179 V180 V181P10-Y164 HydrophobicContact CB-CD1 3.91Å; P10-Y164 HydrophobicContact CG-CD1 4.49Å; A12-Y164 HydrophobicContact CB-CD1 3.88Å; A12-Y164 HydrophobicContact CB-CE1 3.59Å; A12-Y164 HydrophobicContact CB-CE2 4.28Å; A12-Y164 HydrophobicContact CB-CG 4.4Å; E161-Y164 WeakPolarHBondContact O-CD2 3.38Å; E161-Y164 PolarHBondContact O-N 3.02Å; E161-Y164 VanDerWaalsContact O-N 3.07Å; S162-Y164 PolarHBondContact O-N 2.89Å; Y164-N166 VanDerWaalsContact C-N 3.29Å; Y164-N166 PolarHBondContact O-N 3.06Å; Y164-I174 HydrophobicContact CD1-CD1 3.82Å; Y164-I174 HydrophobicContact CD2-CD1 3.43Å; Y164-I174 VanDerWaalsContact CD2-CD1 3.43Å; Y164-I174 HydrophobicContact CE1-CD1 3.8Å; Y164-I174 HydrophobicContact CE1-CG2 4.45Å; Y164-I174 HydrophobicContact CE2-CD1 3.45Å; Y164-I174 VanDerWaalsContact CE2-CD1 3.45Å; Y164-I174 HydrophobicContact CG-CD1 3.61Å; Y164-D178 PolarHBondContact OH-O 3.37Å; Y164-N179 WeakPolarHBondContact OH-CA 3.32Å; Y164-V180 HydrophobicContact CE2-CG2 4.09Å; Y164-V180 WeakPolarHBondContact OH-CG2 3.33Å; Y164-V180 PolarHBondContact OH-N 2.79Å; Y164-V181 HydrophobicContact CD2-CG2 4.36Å; Y164-V181 HydrophobicContact CE2-CG2 3.86Å
165A68.9Low77.1Confident61 Ų6185.3 Ų85.350%0.50444%0.437SS..  trans-66.582.9-171.700000113.1V163V163-A165 PolarHBondContact O-N 3.14Å
166N56.6Low76.3Confident133 Ų13393.7 Ų93.771%0.71148%0.478SS*.  trans-146.5102.3148.6-105.9-23.8000104.9Y164 F168Y164-N166 VanDerWaalsContact C-N 3.29Å; Y164-N166 PolarHBondContact O-N 3.06Å; N166-F168 PolarHBondContact O-N 3.46Å
167K50.8Low75.6Confident215 Ų21598.4 Ų98.494%0.93550%0.504SS*.  trans-68.443.9179.3-68.7-179176.2176.30112.5L169K167-L169 VanDerWaalsContact C-N 3.27Å; K167-L169 PolarHBondContact O-N 2.86Å; K167-L169 VanDerWaalsContact O-N 3.09Å
168F50.1Low75Confident159 Ų15999 Ų9970%0.69751%0.507SS*.  trans-81.486162.6-102.2-89000108.3N166N166-F168 PolarHBondContact O-N 3.46Å
169L47.9Very low74.6Confident132 Ų13297.3 Ų97.369%0.69150%0.502SS*.  trans53.1120.3151.1-65.8156.6000116K167 R171K167-L169 VanDerWaalsContact C-N 3.27Å; K167-L169 PolarHBondContact O-N 2.86Å; K167-L169 VanDerWaalsContact O-N 3.09Å; L169-R171 PolarHBondContact O-N 3.1Å
170G50Low74.4Confident93 Ų9397.1 Ų97.196%0.95950%0.501SS*.THydrogen-bonded Turntrans-57.463.1177.400000115.8
171R53.8Low74.3Confident233 Ų23396.9 Ų96.988%0.87951%0.505SS*.THydrogen-bonded Turntrans-147.3-11.5-179-71.9-168178.4-174.20112.8L169 Q173L169-R171 PolarHBondContact O-N 3.1Å; R171-Q173 PolarHBondContact O-N 2.84Å
172M59.1Low74.5Confident98 Ų9890.9 Ų90.948%0.48348%0.482SS..  trans-78.2106.7170.4-90.6-163-68.200110.1I174M172-I174 PolarHBondContact O-N 2.8Å
173Q69.1Low74.7Confident184 Ų18489.9 Ų89.986%0.8647%0.472SS*.  trans-70.2110.1162.7-69.6-178.94.300107.7R171 P175R171-Q173 PolarHBondContact O-N 2.84Å; Q173-P175 WeakPolarHBondContact O-CD 3.34Å
174I77.4Confident75Confident35 Ų3589.9 Ų89.918%0.17947%0.472CS..  trans-65.5121169-54.8179.6000106.4P10 Y164 M172 M176 D178 N179P10-I174 HydrophobicContact CG-CD1 4.39Å; P10-I174 HydrophobicContact CG-CG1 3.97Å; Y164-I174 HydrophobicContact CD1-CD1 3.82Å; Y164-I174 HydrophobicContact CD2-CD1 3.43Å; Y164-I174 VanDerWaalsContact CD2-CD1 3.43Å; Y164-I174 HydrophobicContact CE1-CD1 3.8Å; Y164-I174 HydrophobicContact CE1-CG2 4.45Å; Y164-I174 HydrophobicContact CE2-CD1 3.45Å; Y164-I174 VanDerWaalsContact CE2-CD1 3.45Å; Y164-I174 HydrophobicContact CG-CD1 3.61Å; M172-I174 PolarHBondContact O-N 2.8Å; I174-M176 PolarHBondContact O-N 2.81Å; I174-D178 HydrophobicContact CG2-CB 4Å; I174-N179 HydrophobicContact CG2-CB 4.11Å
175P81.3Confident75.4Confident64 Ų6488.8 Ų88.842%0.41647%0.467SS..  trans-52.5141.7177-2634.4000110.2Q173 N177 D178 N179Q173-P175 WeakPolarHBondContact O-CD 3.34Å; P175-N177 PolarHBondContact O-N 2.79Å; P175-D178 HydrophobicContact CB-CB 4.37Å; P175-D178 WeakPolarHBondContact O-CA 3.49Å; P175-D178 PolarHBondContact O-N 2.92Å; P175-N179 PolarHBondContact O-N 3.46Å; P175-N179 VanDerWaalsContact O-N 3.08Å
176M81.9Confident76.8Confident176 Ų17685.9 Ų85.987%0.86744%0.443SS*.THydrogen-bonded Turntrans-54.4-33.7-176.8-172.2172.9-17800112.7I174 D178 N179I174-M176 PolarHBondContact O-N 2.81Å; M176-D178 VanDerWaalsContact C-N 3.32Å; M176-D178 PolarHBondContact O-N 3.08Å; M176-N179 PolarHBondContact O-N 3.41Å
177N84Confident78.9Confident101 Ų10179.5 Ų79.554%0.5441%0.41SS..THydrogen-bonded Turntrans-70.2-26.4176.4-65.9-14.3000113.3P175 P364 T366P175-N177 PolarHBondContact O-N 2.79Å; N177-P364 VanDerWaalsContact O-CB 3.25Å; N177-P364 WeakPolarHBondContact O-CB 3.45Å; N177-T366 HydrophobicContact CB-CG2 4.09Å; N177-T366 PolarHBondContact O-OG1 3.15Å
178D85.8Confident81.1Confident12 Ų1269.3 Ų69.36%0.06437%0.365CS..THydrogen-bonded Turntrans-95.6-7.8-179-59.3-9.9000112R9 Y164 I174 P175 M176 P364 H367R9-D178 IonicContact CZ-OD1 3.99Å; R9-D178 IonicContact CZ-OD2 3.18Å; R9-D178 IonicContact NE-OD2 2.76Å; R9-D178 PolarHBondContact NE-OD2 3.34Å; R9-D178 IonicContact NH2-OD1 3.19Å; R9-D178 PolarHBondContact NH2-OD1 2.8Å; R9-D178 IonicContact NH2-OD2 2.78Å; R9-D178 PolarHBondContact NH2-OD2 3.15Å; Y164-D178 PolarHBondContact OH-O 3.37Å; I174-D178 HydrophobicContact CG2-CB 4Å; P175-D178 HydrophobicContact CB-CB 4.37Å; P175-D178 WeakPolarHBondContact O-CA 3.49Å; P175-D178 PolarHBondContact O-N 2.92Å; M176-D178 VanDerWaalsContact C-N 3.32Å; M176-D178 PolarHBondContact O-N 3.08Å; D178-P364 WeakPolarHBondContact O-CG 3.31Å; D178-H367 IonicContact OD1-CD2 3.31Å; D178-H367 IonicContact OD1-CE1 3.7Å; D178-H367 IonicContact OD1-NE2 2.63Å; D178-H367 PolarHBondContact OD1-NE2 2.84Å
179N89.7Confident83.5Confident60 Ų6061.7 Ų61.732%0.32133%0.332SS..  trans-78.3122-176.3-170.85.7000111.5Y164 I174 P175 M176 V181Y164-N179 WeakPolarHBondContact OH-CA 3.32Å; I174-N179 HydrophobicContact CG2-CB 4.11Å; P175-N179 PolarHBondContact O-N 3.46Å; P175-N179 VanDerWaalsContact O-N 3.08Å; M176-N179 PolarHBondContact O-N 3.41Å; N179-V181 VanDerWaalsContact OD1-CB 3.28Å; N179-V181 WeakPolarHBondContact OD1-CB 3.41Å; N179-V181 VanDerWaalsContact OD1-CG2 3.29Å; N179-V181 WeakPolarHBondContact OD1-CG2 3.42Å; N179-V181 PolarHBondContact OD1-N 2.93Å
180V93.8Very high85.9Confident0 Ų055.4 Ų55.40%030%0.299CS..  trans-106.9-3.7176.3-48.40000112.8A12 I159 V163 Y164 G182 N183 I362 P364A12-V180 HydrophobicContact CB-CG2 3.53Å; I159-V180 HydrophobicContact CD1-CG2 4.47Å; I159-V180 HydrophobicContact CG2-CG2 3.95Å; V163-V180 HydrophobicContact CG2-CG2 4.22Å; Y164-V180 HydrophobicContact CE2-CG2 4.09Å; Y164-V180 WeakPolarHBondContact OH-CG2 3.33Å; Y164-V180 PolarHBondContact OH-N 2.79Å; V180-G182 PolarHBondContact O-N 3.14Å; V180-N183 VanDerWaalsContact O-CB 3.26Å; V180-N183 WeakPolarHBondContact O-CB 3.41Å; V180-N183 PolarHBondContact O-N 2.95Å; V180-I362 HydrophobicContact CB-CG2 4.11Å; V180-I362 HydrophobicContact CG1-CG2 3.94Å; V180-I362 HydrophobicContact CG2-CB 4.4Å; V180-I362 HydrophobicContact CG2-CD1 4.27Å; V180-I362 HydrophobicContact CG2-CG2 4.21Å; V180-P364 HydrophobicContact CG1-CB 3.97Å; V180-P364 HydrophobicContact CG1-CG 3.89Å
181V94.4Very high88.2Confident54 Ų5451.4 Ų51.433%0.32726%0.255SS..THydrogen-bonded Turntrans-60.8131.8177.4-178.20000109.5E161 Y164 N179 N183E161-V181 HydrophobicContact CB-CG2 4.13Å; Y164-V181 HydrophobicContact CD2-CG2 4.36Å; Y164-V181 HydrophobicContact CE2-CG2 3.86Å; N179-V181 VanDerWaalsContact OD1-CB 3.28Å; N179-V181 WeakPolarHBondContact OD1-CB 3.41Å; N179-V181 VanDerWaalsContact OD1-CG2 3.29Å; N179-V181 WeakPolarHBondContact OD1-CG2 3.42Å; N179-V181 PolarHBondContact OD1-N 2.93Å; V181-N183 VanDerWaalsContact C-N 3.26Å; V181-N183 PolarHBondContact O-N 2.97Å
182G95.4Very high90.3Very high19 Ų1940.3 Ų40.320%0.19621%0.213CC..THydrogen-bonded Turntrans85.3-11.1-177.600000114.6I159 V180 Y224I159-G182 PolarHBondContact O-N 2.97Å; V180-G182 PolarHBondContact O-N 3.14Å; G182-Y224 WeakPolarHBondContact O-CE1 3.29Å
183N96.6Very high92.2Very high35 Ų3536.3 Ų36.319%0.18719%0.194CC..  trans-70153173.2-68-13.2000110.8I159 V180 V181I159-N183 HydrophobicContact CD1-CB 4.16Å; I159-N183 WeakPolarHBondContact CG1-O 3.4Å; I159-N183 PolarHBondContact N-O 3.28Å; V180-N183 VanDerWaalsContact O-CB 3.26Å; V180-N183 WeakPolarHBondContact O-CB 3.41Å; V180-N183 PolarHBondContact O-N 2.95Å; V181-N183 VanDerWaalsContact C-N 3.26Å; V181-N183 PolarHBondContact O-N 2.97Å
184P98.3Very high93.4Very high0 Ų035.5 Ų35.50%018%0.183CC..EExtended strand (participates in β ladder)trans-78.8154.4176.132.6-32.3000111.2V156 L157 V220 Y224 I226 V231 P232V156-P184 HydrophobicContact CG1-CB 4.22Å; L157-P184 CarbonylContact O-C 3.49Å; L157-P184 WeakPolarHBondContact O-CA 3.43Å; P184-V220 HydrophobicContact CB-CG1 3.63Å; P184-V220 HydrophobicContact CG-CG1 3.59Å; P184-Y224 HydrophobicContact CB-CD1 4.28Å; P184-Y224 HydrophobicContact CB-CD2 4.04Å; P184-Y224 HydrophobicContact CB-CE1 4.12Å; P184-Y224 HydrophobicContact CB-CE2 3.9Å; P184-Y224 HydrophobicContact CB-CG 4.24Å; P184-Y224 HydrophobicContact CG-CD1 3.98Å; P184-Y224 HydrophobicContact CG-CD2 3.93Å; P184-Y224 HydrophobicContact CG-CE1 4.33Å; P184-Y224 HydrophobicContact CG-CE2 4.3Å; P184-Y224 HydrophobicContact CG-CG 3.76Å; P184-I226 HydrophobicContact CG-CD1 3.81Å; P184-V231 HydrophobicContact CG-CG1 4.26Å; P184-V231 HydrophobicContact CG-CG2 4.43Å; P184-P232 VanDerWaalsContact O-CD 3.23Å; P184-P232 WeakPolarHBondContact O-CD 3.44Å
185L98.7Very high94.3Very high0 Ų035.6 Ų35.60%018%0.183CC..EExtended strand (participates in β ladder)trans-132.4122.3165.5167.765000106.8F14 F117 L157 I159 V187 P232 L322F14-L185 HydrophobicContact CE1-CD2 4.4Å; F14-L185 HydrophobicContact CE2-CD2 4Å; F14-L185 HydrophobicContact CZ-CD1 4.2Å; F14-L185 HydrophobicContact CZ-CD2 3.88Å; F117-L185 HydrophobicContact CD1-CD2 4.36Å; F117-L185 HydrophobicContact CE1-CD2 3.73Å; F117-L185 HydrophobicContact CZ-CD2 4.18Å; L157-L185 HydrophobicContact CB-CB 4.4Å; L157-L185 PolarHBondContact N-O 2.78Å; L157-L185 PolarHBondContact O-N 2.89Å; I159-L185 HydrophobicContact CD1-CB 4.41Å; I159-L185 HydrophobicContact CG1-CB 4.31Å; L185-V187 HydrophobicContact CD2-CG2 4.06Å; L185-V187 HydrophobicContact CG-CG2 3.9Å; L185-P232 HydrophobicContact CD1-CB 3.74Å; L185-L322 HydrophobicContact CD1-CD1 4.48Å
186V98.9Very high94.9Very high0 Ų034.3 Ų34.30%018%0.175CC..EExtended strand (participates in β ladder)trans-94121.7176174.20000108.8V156 V216 L217 V220 V231 P232 V233 L234V156-V186 HydrophobicContact CG2-CG2 4.33Å; V186-V216 HydrophobicContact CG2-CG1 4.47Å; V186-L217 HydrophobicContact CG2-CD2 3.96Å; V186-V220 HydrophobicContact CG2-CG2 4.45Å; V186-V231 HydrophobicContact CB-CG1 4.46Å; V186-V231 HydrophobicContact CG2-CG1 3.7Å; V186-P232 PolarHBondContact N-O 2.89Å; V186-V233 HydrophobicContact CB-CG2 4.29Å; V186-V233 HydrophobicContact CG1-CG1 4.48Å; V186-V233 CarbonylContact O-C 3.58Å; V186-V233 WeakPolarHBondContact O-CA 3.48Å; V186-L234 PolarHBondContact O-N 2.95Å
187V98.9Very high95.6Very high0 Ų032.6 Ų32.60%017%0.165CC..EExtended strand (participates in β ladder)trans-118.6116.7176-175.40000108.2V60 T62 I110 C154 A155 L157 L185 L234V60-V187 HydrophobicContact CG1-CG1 3.84Å; V60-V187 HydrophobicContact CG1-CG2 4.25Å; T62-V187 HydrophobicContact CG2-CG1 3.94Å; I110-V187 HydrophobicContact CD1-CG1 4.39Å; I110-V187 WeakPolarHBondContact CD1-O 3.42Å; I110-V187 HydrophobicContact CG2-CG1 4.24Å; C154-V187 CarbonylContact C-O 3.41Å; C154-V187 WeakPolarHBondContact CA-O 3.15Å; A155-V187 PolarHBondContact N-O 3.2Å; A155-V187 PolarHBondContact O-N 3.01Å; L157-V187 HydrophobicContact CD1-CG2 3.91Å; L157-V187 HydrophobicContact CG-CG2 4.47Å; L185-V187 HydrophobicContact CD2-CG2 4.06Å; L185-V187 HydrophobicContact CG-CG2 3.9Å; V187-L234 HydrophobicContact CG1-CB 4.46Å; V187-L234 HydrophobicContact CG2-CD1 4.43Å
188A98.9Very high96.2Very high0 Ų029.3 Ų29.30%015%0.146CC..EExtended strand (participates in β ladder)trans-112147.217300000110.6L153 C154 V213 L234 I235 C236L153-A188 CarbonylContact O-C 3.47Å; L153-A188 VanDerWaalsContact O-CA 3.29Å; L153-A188 WeakPolarHBondContact O-CA 3.36Å; C154-A188 HydrophobicContact CB-CB 4.2Å; A188-V213 HydrophobicContact CB-CG2 4Å; A188-L234 PolarHBondContact N-O 3.34Å; A188-I235 HydrophobicContact CB-CG1 4.37Å; A188-I235 HydrophobicContact CB-CG2 4.46Å; A188-I235 WeakPolarHBondContact O-CA 3.47Å; A188-C236 PolarHBondContact O-N 3.35Å
189T98.9Very high96.8Very high0 Ų029 Ų290%015%0.145CC..EExtended strand (participates in β ladder)trans-132.9145.3167.7-172.20000111.1Q64 C108 I110 G152 L153 C236Q64-T189 PolarHBondContact NE2-OG1 2.99Å; C108-T189 HydrophobicContact CB-CG2 3.75Å; I110-T189 HydrophobicContact CD1-CG2 3.99Å; I110-T189 HydrophobicContact CG1-CG2 3.63Å; G152-T189 CarbonylContact C-O 3.58Å; G152-T189 VanDerWaalsContact CA-O 3.25Å; G152-T189 WeakPolarHBondContact CA-O 3.49Å; L153-T189 HydrophobicContact CB-CG2 4.04Å; L153-T189 PolarHBondContact N-O 2.93Å; L153-T189 PolarHBondContact O-N 3.26Å; T189-C236 CarbonylContact C-O 3.56Å; T189-C236 WeakPolarHBondContact CA-O 3.44Å; T189-C236 PolarHBondContact OG1-O 2.64Å
190A98.6Very high97.1Very high0 Ų026.1 Ų26.10%013%0.129CC..EExtended strand (participates in β ladder)trans-138.5155.8176.100000111.7F127 I192 L209 C236 G237 D238F127-A190 HydrophobicContact CZ-CB 4.38Å; A190-I192 HydrophobicContact CB-CD1 4.14Å; A190-L209 HydrophobicContact CB-CD1 4.28Å; A190-L209 HydrophobicContact CB-CD2 3.76Å; A190-C236 PolarHBondContact N-O 2.8Å; A190-C236 VanDerWaalsContact N-O 3.1Å; A190-G237 VanDerWaalsContact O-CA 3.28Å; A190-G237 WeakPolarHBondContact O-CA 3.33Å; A190-D238 PolarHBondContact O-N 3.4Å
191H98.3Very high97.3Very high9 Ų926.1 Ų26.14%0.04213%0.129CC..EExtended strand (participates in β ladder)trans-124.697.7166.7-175.7174.2000107.6Q64 E65 N150 I151 D238Q64-H191 HydrophobicContact CB-CB 4.24Å; Q64-H191 HydrophobicContact CG-CB 4.08Å; E65-H191 IonicContact OE1-CE1 2.92Å; E65-H191 PolarHBondContact OE1-CE1 3.33Å; N150-H191 WeakPolarHBondContact CB-O 3.44Å; N150-H191 PolarHBondContact ND2-O 3.37Å; I151-H191 PolarHBondContact O-N 3.38Å; H191-D238 WeakPolarHBondContact CA-O 3.43Å; H191-D238 IonicContact CD2-OD2 3.8Å; H191-D238 IonicContact NE2-OD2 3.51Å
192I98.5Very high97.5Very high0 Ų024 Ų240%012%0.116CC..  trans-76.2155.1-175.6-57.6-60.8000110.4F127 A190 W194 K202 Q205 D238 F239 N240F127-I192 HydrophobicContact CE2-CD1 3.87Å; F127-I192 HydrophobicContact CZ-CD1 4.1Å; A190-I192 HydrophobicContact CB-CD1 4.14Å; I192-W194 PolarHBondContact O-N 3.47Å; I192-K202 HydrophobicContact CG2-CB 3.73Å; I192-K202 HydrophobicContact CG2-CG 3.98Å; I192-Q205 HydrophobicContact CD1-CB 3.91Å; I192-Q205 HydrophobicContact CG2-CB 4.4Å; I192-D238 PolarHBondContact N-O 3.45Å; I192-F239 HydrophobicContact CG1-CB 4.47Å; I192-F239 HydrophobicContact CG1-CD1 3.81Å; I192-F239 HydrophobicContact CG1-CE1 4.35Å; I192-F239 HydrophobicContact CG1-CG 4.3Å; I192-N240 PolarHBondContact O-ND2 2.88Å
193H98.4Very high97.7Very high14 Ų1423 Ų237%0.06511%0.106CC..  trans-51.6138.5-179-170.348.6000112.8R148 N150 D195 F198 V201 K202 N240R148-H193 VanDerWaalsContact CD-CE1 3.5Å; R148-H193 WeakPolarHBondContact CD-CE1 3.45Å; R148-H193 PolarHBondContact NE-CE1 2.74Å; R148-H193 VanDerWaalsContact NE-CE1 3.31Å; R148-H193 PolarHBondContact NE-NE2 2.95Å; R148-H193 VanDerWaalsContact NE-NE2 3.11Å; N150-H193 PolarHBondContact ND2-N 3.34Å; N150-H193 WeakPolarHBondContact OD1-CB 3.46Å; H193-D195 WeakPolarHBondContact NE2-CB 3.44Å; H193-F198 AromaticContact NE2-CG 3.94Å; H193-V201 HydrophobicContact CB-CG1 4.02Å; H193-K202 WeakPolarHBondContact O-CD 3Å; H193-K202 WeakPolarHBondContact O-CE 3.46Å; H193-K202 VanDerWaalsContact O-CG 3.3Å; H193-K202 WeakPolarHBondContact O-CG 3.05Å; H193-N240 VanDerWaalsContact O-CB 3.31Å; H193-N240 WeakPolarHBondContact O-CB 3.34Å
194W95.8Very high97.8Very high166 Ų16621.4 Ų21.463%0.62910%0.097SC*.  trans-86.1-35.8-169.668.8-91.4000113.9I192 P196 K202I192-W194 PolarHBondContact O-N 3.47Å; W194-P196 WeakPolarHBondContact O-CD 3.44Å; W194-K202 WeakPolarHBondContact O-CE 3.16Å; W194-K202 PolarHBondContact O-NZ 2.99Å
195D96.1Very high97.8Very high37 Ų3721.4 Ų21.420%0.19810%0.097CC..  trans-58118.9-166.5-170.1-28.9000111.6H193 E197 F198 K202H193-D195 WeakPolarHBondContact NE2-CB 3.44Å; D195-E197 PolarHBondContact O-N 3.19Å; D195-E197 PolarHBondContact OD1-N 3.38Å; D195-F198 HydrophobicContact CB-CB 4.42Å; D195-F198 HydrophobicContact CB-CD2 3.68Å; D195-F198 HydrophobicContact CB-CE2 4.42Å; D195-F198 HydrophobicContact CB-CG 4.45Å; D195-F198 VanDerWaalsContact CG-CD2 3.41Å; D195-F198 PolarHBondContact O-N 3.42Å; D195-F198 WeakPolarHBondContact OD2-CD2 3.37Å; D195-F198 WeakPolarHBondContact OD2-CE2 3.47Å; D195-K202 WeakPolarHBondContact O-CE 3.3Å; D195-K202 PolarHBondContact O-NZ 2.86Å
196P93.9Very high97.8Very high38 Ų3821.4 Ų21.425%0.24710%0.097CC..G310 helixtrans-54.4-34.1178.3-21.431.2000112.3W194 F198 L398 C400W194-P196 WeakPolarHBondContact O-CD 3.44Å; P196-F198 PolarHBondContact O-N 3.18Å; P196-L398 HydrophobicContact CB-CD2 4.38Å; P196-L398 HydrophobicContact CG-CD2 4.19Å; P196-C400 CarbonylContact C-O 3.56Å; P196-C400 WeakPolarHBondContact CA-O 3.15Å; P196-C400 WeakPolarHBondContact CB-OXT 3.42Å; P196-C400 CarbonylContact O-C 3.01Å; P196-C400 WeakPolarHBondContact O-CB 3.44Å
197E95.6Very high97.7Very high140 Ų14021.4 Ų21.465%0.65410%0.097SC*.G310 helixtrans-70-3.7179.1-62.1-156.3130.100114.3D195 K264D195-E197 PolarHBondContact O-N 3.19Å; D195-E197 PolarHBondContact OD1-N 3.38Å; E197-K264 PolarHBondContact O-NZ 2.95Å
198F97.1Very high97.7Very high31 Ų3121.4 Ų21.414%0.13610%0.097CC..G310 helixtrans-118.236.9-174.9-70.7-95.5000113.4R144 H193 D195 P196 D200 V201 K202R144-F198 VanDerWaalsContact NH2-CD1 3.31Å; H193-F198 AromaticContact NE2-CG 3.94Å; D195-F198 HydrophobicContact CB-CB 4.42Å; D195-F198 HydrophobicContact CB-CD2 3.68Å; D195-F198 HydrophobicContact CB-CE2 4.42Å; D195-F198 HydrophobicContact CB-CG 4.45Å; D195-F198 VanDerWaalsContact CG-CD2 3.41Å; D195-F198 PolarHBondContact O-N 3.42Å; D195-F198 WeakPolarHBondContact OD2-CD2 3.37Å; D195-F198 WeakPolarHBondContact OD2-CE2 3.47Å; P196-F198 PolarHBondContact O-N 3.18Å; F198-D200 WeakPolarHBondContact CA-OD1 3.33Å; F198-D200 PolarHBondContact O-N 3.09Å; F198-V201 HydrophobicContact CB-CB 4.02Å; F198-V201 HydrophobicContact CB-CG2 3.97Å; F198-V201 HydrophobicContact CD1-CG2 3.59Å; F198-V201 HydrophobicContact CG-CG2 4.24Å; F198-V201 WeakPolarHBondContact O-CA 3.49Å; F198-V201 WeakPolarHBondContact O-CB 3.15Å; F198-V201 PolarHBondContact O-N 3.03Å; F198-K202 WeakPolarHBondContact O-CG 3.37Å; F198-K202 PolarHBondContact O-N 3.13Å
199C97.3Very high97.7Very high5 Ų521.4 Ų21.43%0.03410%0.097CC..Hα-helixtrans-48-31.3170.749.20000113.9K202 L203 D262 K264 C400C199-K202 PolarHBondContact O-N 2.92Å; C199-L203 VanDerWaalsContact O-CB 3.3Å; C199-L203 WeakPolarHBondContact O-CB 3.31Å; C199-L203 PolarHBondContact O-N 3.23Å; C199-D262 HydrophobicContact CB-CB 4.07Å; C199-K264 WeakPolarHBondContact SG-CE 3.35Å; C199-C400 HydrophobicContact CB-CB 3.5Å; C199-C400 VanDerWaalsContact CB-CB 3.5Å; C199-C400 WeakPolarHBondContact CB-SG 3.27Å; C199-C400 WeakPolarHBondContact SG-CB 3.28Å; C199-C400 CovalentContact SG-SG 2.06Å; C199-C400 PolarHBondContact SG-SG 3.36Å
200D97.4Very high97.7Very high0 Ų021.4 Ų21.40%010%0.098CC..Hα-helixtrans-68.2-41.4174.460.8-47.9000112.9R144 F198 L203 V204 D262 K264 F266R144-D200 IonicContact CZ-OD1 3.79Å; R144-D200 IonicContact CZ-OD2 3.29Å; R144-D200 VanDerWaalsContact CZ-OD2 3.29Å; R144-D200 IonicContact NE-OD1 3.9Å; R144-D200 IonicContact NE-OD2 2.66Å; R144-D200 PolarHBondContact NE-OD2 3.19Å; R144-D200 VanDerWaalsContact NH2-CG 3.35Å; R144-D200 IonicContact NH2-OD1 2.83Å; R144-D200 PolarHBondContact NH2-OD1 2.69Å; R144-D200 IonicContact NH2-OD2 3.08Å; R144-D200 PolarHBondContact NH2-OD2 2.94Å; R144-D200 VanDerWaalsContact NH2-OD2 3.08Å; F198-D200 WeakPolarHBondContact CA-OD1 3.33Å; F198-D200 PolarHBondContact O-N 3.09Å; D200-L203 PolarHBondContact O-N 3.29Å; D200-V204 VanDerWaalsContact O-CG2 3.3Å; D200-V204 WeakPolarHBondContact O-CG2 3.49Å; D200-V204 PolarHBondContact O-N 2.78Å; D200-D262 WeakPolarHBondContact CA-O 3.29Å; D200-D262 WeakPolarHBondContact CB-O 3.47Å; D200-D262 PolarHBondContact N-O 2.88Å; D200-D262 VanDerWaalsContact N-O 3.12Å; D200-K264 HydrophobicContact CB-CB 4.13Å; D200-K264 HydrophobicContact CB-CD 4.32Å; D200-K264 HydrophobicContact CB-CG 4.22Å; D200-F266 HydrophobicContact CB-CD2 3.92Å; D200-F266 HydrophobicContact CB-CE2 4.19Å; D200-F266 WeakPolarHBondContact OD2-CE2 3.5Å
201V98.1Very high97.6Very high0 Ų023 Ų230%011%0.105CC..Hα-helixtrans-65.9-43.7174176.20000110.3R144 V145 R148 H193 F198 L203 V204 Q205R144-V201 HydrophobicContact CB-CG2 4.03Å; R144-V201 WeakPolarHBondContact O-CG2 3.44Å; V145-V201 HydrophobicContact CG2-CB 4.28Å; V145-V201 HydrophobicContact CG2-CG1 4.13Å; V145-V201 HydrophobicContact CG2-CG2 3.94Å; R148-V201 HydrophobicContact CG-CG1 4.13Å; H193-V201 HydrophobicContact CB-CG1 4.02Å; F198-V201 HydrophobicContact CB-CB 4.02Å; F198-V201 HydrophobicContact CB-CG2 3.97Å; F198-V201 HydrophobicContact CD1-CG2 3.59Å; F198-V201 HydrophobicContact CG-CG2 4.24Å; F198-V201 WeakPolarHBondContact O-CA 3.49Å; F198-V201 WeakPolarHBondContact O-CB 3.15Å; F198-V201 PolarHBondContact O-N 3.03Å; V201-L203 VanDerWaalsContact C-N 3.31Å; V201-L203 PolarHBondContact O-N 2.91Å; V201-V204 PolarHBondContact O-N 3.24Å; V201-Q205 HydrophobicContact CG1-CG 4.17Å; V201-Q205 WeakPolarHBondContact O-CB 3.48Å; V201-Q205 VanDerWaalsContact O-CG 3.3Å; V201-Q205 WeakPolarHBondContact O-CG 3.46Å; V201-Q205 PolarHBondContact O-N 3.44Å
202K98.6Very high97.6Very high9 Ų923.4 Ų23.44%0.03911%0.107CC..Hα-helixtrans-57.6-46.3177.8-59.7-178.3-171.61790111.1I192 H193 W194 D195 F198 C199 S206 N240 V247I192-K202 HydrophobicContact CG2-CB 3.73Å; I192-K202 HydrophobicContact CG2-CG 3.98Å; H193-K202 WeakPolarHBondContact O-CD 3Å; H193-K202 WeakPolarHBondContact O-CE 3.46Å; H193-K202 VanDerWaalsContact O-CG 3.3Å; H193-K202 WeakPolarHBondContact O-CG 3.05Å; W194-K202 WeakPolarHBondContact O-CE 3.16Å; W194-K202 PolarHBondContact O-NZ 2.99Å; D195-K202 WeakPolarHBondContact O-CE 3.3Å; D195-K202 PolarHBondContact O-NZ 2.86Å; F198-K202 WeakPolarHBondContact O-CG 3.37Å; F198-K202 PolarHBondContact O-N 3.13Å; C199-K202 PolarHBondContact O-N 2.92Å; K202-S206 WeakPolarHBondContact O-CB 3.33Å; K202-S206 PolarHBondContact O-N 3.5Å; K202-S206 PolarHBondContact O-OG 3.42Å; K202-N240 HydrophobicContact CD-CB 4.4Å; K202-N240 WeakPolarHBondContact CD-O 3.37Å; K202-N240 WeakPolarHBondContact CE-O 3.25Å; K202-N240 PolarHBondContact NZ-O 3.5Å; K202-V247 HydrophobicContact CB-CG2 3.91Å
203L98.5Very high97.6Very high0 Ų023.4 Ų23.40%011%0.107CC..Hα-helixtrans-65.5-46.1178-179.652.3000112.2C199 D200 V201 S206 M207 G246 V247 Y250 I256 D262 L263C199-L203 VanDerWaalsContact O-CB 3.3Å; C199-L203 WeakPolarHBondContact O-CB 3.31Å; C199-L203 PolarHBondContact O-N 3.23Å; D200-L203 PolarHBondContact O-N 3.29Å; V201-L203 VanDerWaalsContact C-N 3.31Å; V201-L203 PolarHBondContact O-N 2.91Å; L203-S206 WeakPolarHBondContact O-CB 3.4Å; L203-S206 PolarHBondContact O-N 2.82Å; L203-M207 HydrophobicContact CD1-CE 3.87Å; L203-M207 HydrophobicContact CD2-CE 4.29Å; L203-M207 HydrophobicContact CG-CE 3.84Å; L203-M207 WeakPolarHBondContact O-CG 3.45Å; L203-M207 PolarHBondContact O-N 2.86Å; L203-G246 WeakPolarHBondContact CD1-O 3.37Å; L203-V247 HydrophobicContact CB-CG2 4.07Å; L203-V247 HydrophobicContact CD1-CG2 4.41Å; L203-Y250 HydrophobicContact CD1-CD1 4.47Å; L203-Y250 HydrophobicContact CD1-CG 4.23Å; L203-I256 HydrophobicContact CD1-CD1 4.32Å; L203-I256 HydrophobicContact CD2-CD1 3.84Å; L203-D262 HydrophobicContact CD2-CB 4.2Å; L203-L263 HydrophobicContact CD2-CD2 3.51Å; L203-L263 HydrophobicContact CD2-CG 3.7Å; L203-L263 HydrophobicContact CG-CD2 4.05Å
204V98.1Very high97.6Very high0 Ų023 Ų230%011%0.106CC..Hα-helixtrans-69.3-37179.31800000112.4M141 V145 D200 V201 S206 M207 M208 F266 L272M141-V204 HydrophobicContact CE-CB 4.08Å; M141-V204 HydrophobicContact CE-CG1 3.37Å; M141-V204 HydrophobicContact CE-CG2 4.25Å; M141-V204 HydrophobicContact SD-CG1 4.25Å; V145-V204 HydrophobicContact CG2-CB 4.47Å; D200-V204 VanDerWaalsContact O-CG2 3.3Å; D200-V204 WeakPolarHBondContact O-CG2 3.49Å; D200-V204 PolarHBondContact O-N 2.78Å; V201-V204 PolarHBondContact O-N 3.24Å; V204-S206 VanDerWaalsContact C-N 3.26Å; V204-S206 PolarHBondContact O-N 2.85Å; V204-M207 WeakPolarHBondContact O-CB 3.45Å; V204-M207 PolarHBondContact O-N 2.97Å; V204-M207 VanDerWaalsContact O-N 3.16Å; V204-M208 HydrophobicContact CG1-CE 3.71Å; V204-M208 WeakPolarHBondContact O-CG 3.38Å; V204-M208 PolarHBondContact O-N 2.86Å; V204-F266 HydrophobicContact CG2-CD1 4.39Å; V204-F266 HydrophobicContact CG2-CD2 4.26Å; V204-F266 HydrophobicContact CG2-CE2 4.37Å; V204-F266 HydrophobicContact CG2-CG 4.24Å; V204-L272 HydrophobicContact CG1-CD2 4.26Å; V204-L272 HydrophobicContact CG2-CD2 3.82Å
205Q98.6Very high97.6Very high0 Ų019.9 Ų19.90%09%0.094CC..Hα-helixtrans-60.5-38.5171.6-74.1-179.5-13.300111.3F127 V145 N150 I192 V201 M208 L209F127-Q205 HydrophobicContact CB-CG 4.11Å; F127-Q205 HydrophobicContact CD2-CB 3.99Å; F127-Q205 HydrophobicContact CD2-CG 3.85Å; F127-Q205 HydrophobicContact CE2-CB 4.23Å; F127-Q205 HydrophobicContact CG-CB 4.27Å; F127-Q205 HydrophobicContact CG-CG 4.07Å; V145-Q205 HydrophobicContact CG1-CG 4.47Å; N150-Q205 PolarHBondContact OD1-NE2 2.85Å; I192-Q205 HydrophobicContact CD1-CB 3.91Å; I192-Q205 HydrophobicContact CG2-CB 4.4Å; V201-Q205 HydrophobicContact CG1-CG 4.17Å; V201-Q205 WeakPolarHBondContact O-CB 3.48Å; V201-Q205 VanDerWaalsContact O-CG 3.3Å; V201-Q205 WeakPolarHBondContact O-CG 3.46Å; V201-Q205 PolarHBondContact O-N 3.44Å; Q205-M208 WeakPolarHBondContact O-CB 3.48Å; Q205-M208 PolarHBondContact O-N 3.07Å; Q205-L209 PolarHBondContact O-N 2.84Å
206S98.6Very high97.8Very high0 Ų018.1 Ų18.10%08%0.084CC..Hα-helixtrans-65.6-36.5174.5-58.40000112.6K202 L203 V204 L209 T210 V247K202-S206 WeakPolarHBondContact O-CB 3.33Å; K202-S206 PolarHBondContact O-N 3.5Å; K202-S206 PolarHBondContact O-OG 3.42Å; L203-S206 WeakPolarHBondContact O-CB 3.4Å; L203-S206 PolarHBondContact O-N 2.82Å; V204-S206 VanDerWaalsContact C-N 3.26Å; V204-S206 PolarHBondContact O-N 2.85Å; S206-L209 WeakPolarHBondContact O-CB 3.28Å; S206-L209 PolarHBondContact O-N 3.26Å; S206-T210 PolarHBondContact O-N 3.39Å; S206-T210 VanDerWaalsContact O-N 3.09Å; S206-T210 PolarHBondContact O-OG1 3.02Å; S206-V247 WeakPolarHBondContact OG-CG1 3.19Å
207M98.3Very high98Very high0 Ų016.5 Ų16.50%07%0.073CC..Hα-helixtrans-65.5-39.2171.4-65.2175.2177.200112.3L203 V204 L209 T210 H211 Y250 I256 L263 L272 F275 I284L203-M207 HydrophobicContact CD1-CE 3.87Å; L203-M207 HydrophobicContact CD2-CE 4.29Å; L203-M207 HydrophobicContact CG-CE 3.84Å; L203-M207 WeakPolarHBondContact O-CG 3.45Å; L203-M207 PolarHBondContact O-N 2.86Å; V204-M207 WeakPolarHBondContact O-CB 3.45Å; V204-M207 PolarHBondContact O-N 2.97Å; V204-M207 VanDerWaalsContact O-N 3.16Å; M207-L209 VanDerWaalsContact C-N 3.34Å; M207-T210 PolarHBondContact O-OG1 2.73Å; M207-T210 VanDerWaalsContact O-OG1 3.08Å; M207-H211 VanDerWaalsContact O-CB 3.22Å; M207-H211 WeakPolarHBondContact O-CB 3.46Å; M207-H211 PolarHBondContact O-N 3.16Å; M207-Y250 HydrophobicContact CB-CE1 4.33Å; M207-Y250 HydrophobicContact CE-CD2 4.34Å; M207-Y250 HydrophobicContact CE-CE2 4.38Å; M207-Y250 HydrophobicContact CG-CD1 4.34Å; M207-Y250 HydrophobicContact CG-CE1 3.8Å; M207-Y250 HydrophobicContact CG-CE2 4.09Å; M207-I256 HydrophobicContact CE-CG2 3.76Å; M207-L263 HydrophobicContact CE-CD2 4.06Å; M207-L272 HydrophobicContact SD-CD2 4.34Å; M207-F275 HydrophobicContact CB-CB 4.28Å; M207-I284 HydrophobicContact CE-CB 4.08Å; M207-I284 HydrophobicContact CE-CD1 3.79Å; M207-I284 HydrophobicContact CE-CG2 3.69Å; M207-I284 HydrophobicContact CG-CG2 4.43Å; M207-I284 HydrophobicContact SD-CD1 4.3Å; M207-I284 HydrophobicContact SD-CG2 3.79Å
208M98.3Very high98.1Very high0 Ų014.1 Ų14.10%06%0.062CC..Hα-helixtrans-65.8-38.7174.7-68.6174-178.900111.5F127 V130 A131 M141 V145 V204 Q205 H211 E212 F275F127-M208 HydrophobicContact CB-SD 4.06Å; F127-M208 HydrophobicContact CD1-CB 3.81Å; F127-M208 HydrophobicContact CE1-CB 4.3Å; V130-M208 HydrophobicContact CB-CG 4.42Å; V130-M208 HydrophobicContact CB-SD 4.16Å; V130-M208 HydrophobicContact CG1-CB 4.13Å; V130-M208 HydrophobicContact CG1-CG 3.87Å; V130-M208 HydrophobicContact CG1-SD 4.17Å; A131-M208 HydrophobicContact CB-CE 3.58Å; A131-M208 HydrophobicContact CB-SD 4.36Å; M141-M208 HydrophobicContact CE-CE 4.24Å; M141-M208 HydrophobicContact SD-CE 3.53Å; M141-M208 VanDerWaalsContact SD-CE 3.53Å; V145-M208 HydrophobicContact CG1-CE 4.11Å; V145-M208 HydrophobicContact CG1-SD 4.38Å; V204-M208 HydrophobicContact CG1-CE 3.71Å; V204-M208 WeakPolarHBondContact O-CG 3.38Å; V204-M208 PolarHBondContact O-N 2.86Å; Q205-M208 WeakPolarHBondContact O-CB 3.48Å; Q205-M208 PolarHBondContact O-N 3.07Å; M208-H211 PolarHBondContact O-N 3.25Å; M208-E212 WeakPolarHBondContact O-CB 3.48Å; M208-E212 WeakPolarHBondContact O-CG 3.46Å; M208-E212 PolarHBondContact O-N 3.21Å; M208-F275 HydrophobicContact CE-CE1 4.35Å; M208-F275 HydrophobicContact CE-CE2 4.08Å; M208-F275 HydrophobicContact CE-CZ 3.65Å; M208-F275 HydrophobicContact CG-CD1 4.26Å; M208-F275 HydrophobicContact CG-CE1 3.79Å; M208-F275 HydrophobicContact CG-CZ 4.01Å
209L98.7Very high98.1Very high0 Ų016.1 Ų16.10%07%0.072CC..Hα-helixtrans-60.9-53176.1178.162.1000111.6F125 F127 A190 Q205 S206 M207 H211 E212 V213 I235 F239F125-L209 HydrophobicContact CD2-CD1 3.82Å; F125-L209 HydrophobicContact CE2-CD1 4.17Å; F127-L209 HydrophobicContact CE1-CB 4.03Å; F127-L209 HydrophobicContact CZ-CB 4.19Å; A190-L209 HydrophobicContact CB-CD1 4.28Å; A190-L209 HydrophobicContact CB-CD2 3.76Å; Q205-L209 PolarHBondContact O-N 2.84Å; S206-L209 WeakPolarHBondContact O-CB 3.28Å; S206-L209 PolarHBondContact O-N 3.26Å; M207-L209 VanDerWaalsContact C-N 3.34Å; L209-H211 VanDerWaalsContact C-N 3.28Å; L209-H211 PolarHBondContact O-N 3.09Å; L209-E212 PolarHBondContact O-N 2.71Å; L209-V213 HydrophobicContact CD1-CG2 4.35Å; L209-V213 VanDerWaalsContact O-CG2 3.31Å; L209-V213 WeakPolarHBondContact O-CG2 3.05Å; L209-V213 PolarHBondContact O-N 2.9Å; L209-I235 HydrophobicContact CD2-CG2 3.73Å; L209-I235 HydrophobicContact CG-CG2 4.39Å; L209-F239 HydrophobicContact CD2-CE1 3.99Å; L209-F239 HydrophobicContact CD2-CZ 4.12Å
210T98.4Very high98.1Very high1 Ų116.1 Ų16.11%0.0067%0.072CC..Hα-helixtrans-65-33.817957.70000112S206 M207 S214 Y250 L251 H286 L288S206-T210 PolarHBondContact O-N 3.39Å; S206-T210 VanDerWaalsContact O-N 3.09Å; S206-T210 PolarHBondContact O-OG1 3.02Å; M207-T210 PolarHBondContact O-OG1 2.73Å; M207-T210 VanDerWaalsContact O-OG1 3.08Å; T210-S214 WeakPolarHBondContact O-CB 3.42Å; T210-S214 PolarHBondContact O-N 3.18Å; T210-S214 PolarHBondContact O-OG 3.17Å; T210-Y250 HydrophobicContact CG2-CE1 3.94Å; T210-Y250 PolarHBondContact OG1-OH 3.02Å; T210-L251 HydrophobicContact CG2-CD2 3.5Å; T210-H286 HydrophobicContact CG2-CB 4.48Å; T210-L288 HydrophobicContact CG2-CD1 4.23Å
211H97.4Very high98.1Very high34 Ų3416.9 Ų16.916%0.1578%0.077CC..Hα-helixtrans-63.3-50.1174.2-177.174.6000112K134 M207 M208 L209 S214 R215 F275K134-H211 WeakPolarHBondContact CE-NE2 3.38Å; K134-H211 PolarHBondContact NZ-CE1 3.13Å; K134-H211 PolarHBondContact NZ-NE2 2.85Å; M207-H211 VanDerWaalsContact O-CB 3.22Å; M207-H211 WeakPolarHBondContact O-CB 3.46Å; M207-H211 PolarHBondContact O-N 3.16Å; M208-H211 PolarHBondContact O-N 3.25Å; L209-H211 VanDerWaalsContact C-N 3.28Å; L209-H211 PolarHBondContact O-N 3.09Å; H211-S214 WeakPolarHBondContact O-CB 3.21Å; H211-S214 PolarHBondContact O-N 3.01Å; H211-R215 PolarHBondContact O-N 3.16Å; H211-F275 HydrophobicContact CB-CD1 4.18Å
212E98.3Very high98.1Very high17 Ų1724.2 Ų24.28%0.07911%0.109CC..Hα-helixtrans-67.4-36.8179.3-74.9-61.7114.700112.2F125 V130 M208 L209 S214 R215 V216F125-E212 HydrophobicContact CB-CB 4.48Å; F125-E212 HydrophobicContact CB-CG 4.45Å; F125-E212 HydrophobicContact CD1-CB 3.58Å; F125-E212 HydrophobicContact CD1-CG 3.99Å; F125-E212 HydrophobicContact CD2-CB 3.99Å; F125-E212 HydrophobicContact CE1-CB 3.66Å; F125-E212 HydrophobicContact CE1-CG 4.46Å; F125-E212 HydrophobicContact CE2-CB 4.04Å; F125-E212 HydrophobicContact CG-CB 3.76Å; F125-E212 HydrophobicContact CG-CG 4.19Å; F125-E212 HydrophobicContact CZ-CB 3.87Å; V130-E212 HydrophobicContact CG2-CG 3.99Å; M208-E212 WeakPolarHBondContact O-CB 3.48Å; M208-E212 WeakPolarHBondContact O-CG 3.46Å; M208-E212 PolarHBondContact O-N 3.21Å; L209-E212 PolarHBondContact O-N 2.71Å; E212-S214 VanDerWaalsContact C-N 3.32Å; E212-S214 PolarHBondContact O-N 2.78Å; E212-R215 WeakPolarHBondContact O-CB 3.08Å; E212-R215 PolarHBondContact O-N 3.32Å; E212-R215 IonicContact OE1-NE 2.63Å; E212-R215 IonicContact OE2-CZ 3.35Å; E212-R215 VanDerWaalsContact OE2-CZ 3.26Å; E212-R215 IonicContact OE2-NE 2.71Å; E212-R215 PolarHBondContact OE2-NE 2.78Å; E212-R215 IonicContact OE2-NH2 2.64Å; E212-R215 PolarHBondContact OE2-NH2 2.72Å; E212-V216 WeakPolarHBondContact O-CG2 3.28Å; E212-V216 PolarHBondContact O-N 3.39Å
213V98.6Very high98Very high0 Ų029.2 Ų29.20%013%0.131CC..Hα-helixtrans-61.1-42.5171.2171.40000110.7F125 A188 L209 R215 V216 L217 V233 I235 L288F125-V213 HydrophobicContact CE2-CG2 3.87Å; F125-V213 HydrophobicContact CZ-CG2 4.4Å; A188-V213 HydrophobicContact CB-CG2 4Å; L209-V213 HydrophobicContact CD1-CG2 4.35Å; L209-V213 VanDerWaalsContact O-CG2 3.31Å; L209-V213 WeakPolarHBondContact O-CG2 3.05Å; L209-V213 PolarHBondContact O-N 2.9Å; V213-R215 VanDerWaalsContact C-N 3.31Å; V213-R215 PolarHBondContact O-N 3.07Å; V213-V216 WeakPolarHBondContact O-CB 3.36Å; V213-V216 PolarHBondContact O-N 3.42Å; V213-V216 VanDerWaalsContact O-N 3.13Å; V213-L217 WeakPolarHBondContact O-CG 3.48Å; V213-L217 PolarHBondContact O-N 3.22Å; V213-V233 HydrophobicContact CG1-CG1 4Å; V213-I235 HydrophobicContact CG1-CD1 4.47Å; V213-I235 HydrophobicContact CG2-CD1 4.24Å; V213-L288 HydrophobicContact CB-CD1 3.93Å; V213-L288 HydrophobicContact CG1-CD1 3.63Å; V213-L288 HydrophobicContact CG1-CD2 4.23Å
214S97.5Very high97.9Very high6 Ų631.5 Ų31.54%0.04214%0.14CC..Hα-helixtrans-62.2-38.7176.5-56.80000112T210 H211 E212 V216 L217 E218T210-S214 WeakPolarHBondContact O-CB 3.42Å; T210-S214 PolarHBondContact O-N 3.18Å; T210-S214 PolarHBondContact O-OG 3.17Å; H211-S214 WeakPolarHBondContact O-CB 3.21Å; H211-S214 PolarHBondContact O-N 3.01Å; E212-S214 VanDerWaalsContact C-N 3.32Å; E212-S214 PolarHBondContact O-N 2.78Å; S214-V216 PolarHBondContact O-N 3.4Å; S214-L217 WeakPolarHBondContact O-CB 3.49Å; S214-L217 PolarHBondContact O-N 3.06Å; S214-E218 PolarHBondContact O-N 2.88Å
215R97.3Very high97.8Very high99 Ų9940.1 Ų40.137%0.37418%0.18SC..Hα-helixtrans-62.4-40.8172.8-173.8-177.967.575.70.4112.2H211 E212 V213 L217 E218 E219H211-R215 PolarHBondContact O-N 3.16Å; E212-R215 WeakPolarHBondContact O-CB 3.08Å; E212-R215 PolarHBondContact O-N 3.32Å; E212-R215 IonicContact OE1-NE 2.63Å; E212-R215 IonicContact OE2-CZ 3.35Å; E212-R215 VanDerWaalsContact OE2-CZ 3.26Å; E212-R215 IonicContact OE2-NE 2.71Å; E212-R215 PolarHBondContact OE2-NE 2.78Å; E212-R215 IonicContact OE2-NH2 2.64Å; E212-R215 PolarHBondContact OE2-NH2 2.72Å; V213-R215 VanDerWaalsContact C-N 3.31Å; V213-R215 PolarHBondContact O-N 3.07Å; R215-L217 VanDerWaalsContact C-N 3.34Å; R215-E218 PolarHBondContact O-N 2.68Å; R215-E219 PolarHBondContact O-N 3.33Å
216V98.6Very high97.5Very high0 Ų041.6 Ų41.60%019%0.188CC..Hα-helixtrans-63.6-42173.5172.60000110.5Y123 F125 V156 V186 E212 V213 S214 E218 E219 V220Y123-V216 HydrophobicContact CD1-CG2 3.89Å; Y123-V216 HydrophobicContact CD2-CG1 4.15Å; Y123-V216 HydrophobicContact CD2-CG2 3.79Å; Y123-V216 HydrophobicContact CE1-CG2 4.01Å; Y123-V216 HydrophobicContact CE2-CG1 3.76Å; Y123-V216 HydrophobicContact CE2-CG2 3.95Å; Y123-V216 HydrophobicContact CG-CG2 3.75Å; F125-V216 HydrophobicContact CE1-CG2 4.04Å; F125-V216 HydrophobicContact CZ-CG2 3.88Å; V156-V216 HydrophobicContact CG2-CG1 3.87Å; V186-V216 HydrophobicContact CG2-CG1 4.47Å; E212-V216 WeakPolarHBondContact O-CG2 3.28Å; E212-V216 PolarHBondContact O-N 3.39Å; V213-V216 WeakPolarHBondContact O-CB 3.36Å; V213-V216 PolarHBondContact O-N 3.42Å; V213-V216 VanDerWaalsContact O-N 3.13Å; S214-V216 PolarHBondContact O-N 3.4Å; V216-E218 VanDerWaalsContact C-N 3.32Å; V216-E218 PolarHBondContact O-N 2.97Å; V216-E219 PolarHBondContact O-N 3.05Å; V216-E219 VanDerWaalsContact O-N 3.13Å; V216-V220 HydrophobicContact CG1-CG2 3.99Å; V216-V220 WeakPolarHBondContact O-CG2 3.31Å; V216-V220 PolarHBondContact O-N 2.93Å
217L98.2Very high97.3Very high4 Ų444.9 Ų44.92%0.02121%0.208CC..Hα-helixtrans-60.7-38.6177.1-69.9-174.6000113V186 V213 S214 R215 E219 V220 S221 Q228 V231 V233 L288V186-L217 HydrophobicContact CG2-CD2 3.96Å; V213-L217 WeakPolarHBondContact O-CG 3.48Å; V213-L217 PolarHBondContact O-N 3.22Å; S214-L217 WeakPolarHBondContact O-CB 3.49Å; S214-L217 PolarHBondContact O-N 3.06Å; R215-L217 VanDerWaalsContact C-N 3.34Å; L217-E219 VanDerWaalsContact C-N 3.31Å; L217-E219 PolarHBondContact O-N 2.63Å; L217-V220 PolarHBondContact O-N 3.31Å; L217-S221 WeakPolarHBondContact O-CB 3.22Å; L217-S221 PolarHBondContact O-N 2.89Å; L217-S221 PolarHBondContact O-OG 3.32Å; L217-Q228 HydrophobicContact CB-CB 4.26Å; L217-Q228 HydrophobicContact CB-CG 4.13Å; L217-V231 HydrophobicContact CD2-CB 3.68Å; L217-V231 HydrophobicContact CD2-CG1 3.51Å; L217-V231 HydrophobicContact CD2-CG2 4.19Å; L217-V233 HydrophobicContact CD1-CG2 4.02Å; L217-V233 HydrophobicContact CD2-CG2 3.78Å; L217-V233 HydrophobicContact CG-CG2 4.36Å; L217-L288 HydrophobicContact CD1-CD2 3.3Å; L217-L288 HydrophobicContact CG-CD2 4.5Å
218E97.5Very high97.1Very high90 Ų9047.4 Ų47.442%0.42122%0.22SC..Hα-helixtrans-60.2-39.5173.8-75.4176.3-159.900113.1S214 R215 V216 S221 K222S214-E218 PolarHBondContact O-N 2.88Å; R215-E218 PolarHBondContact O-N 2.68Å; V216-E218 VanDerWaalsContact C-N 3.32Å; V216-E218 PolarHBondContact O-N 2.97Å; E218-S221 PolarHBondContact O-OG 3.37Å; E218-K222 WeakPolarHBondContact O-CD 3.43Å; E218-K222 VanDerWaalsContact O-CG 3.28Å; E218-K222 WeakPolarHBondContact O-CG 3.44Å; E218-K222 PolarHBondContact O-N 3.39Å
219E98.1Very high96.8Very high74 Ų7451.8 Ų51.835%0.34624%0.24SC..Hα-helixtrans-70.2-48177.8-169.1-173.9155.400110.8K121 Y123 R215 V216 L217 K222 K223K121-E219 IonicContact NZ-OE1 3.52Å; K121-E219 PolarHBondContact NZ-OE1 2.87Å; K121-E219 IonicContact NZ-OE2 2.68Å; K121-E219 PolarHBondContact NZ-OE2 2.99Å; Y123-E219 WeakPolarHBondContact CE1-OE2 3.33Å; Y123-E219 PolarHBondContact OH-OE1 3Å; Y123-E219 PolarHBondContact OH-OE2 2.9Å; R215-E219 PolarHBondContact O-N 3.33Å; V216-E219 PolarHBondContact O-N 3.05Å; V216-E219 VanDerWaalsContact O-N 3.13Å; L217-E219 VanDerWaalsContact C-N 3.31Å; L217-E219 PolarHBondContact O-N 2.63Å; E219-K222 PolarHBondContact O-N 3.41Å; E219-K223 PolarHBondContact O-N 3.43Å; E219-K223 VanDerWaalsContact O-N 3.08Å
220V98.1Very high96.6Very high4 Ų453.8 Ų53.82%0.02425%0.25CC..Hα-helixtrans-63.7-45.4-179.5172.40000110.8V156 P184 V186 V216 L217 K222 K223 Y224 V231V156-V220 HydrophobicContact CB-CG2 4.47Å; V156-V220 HydrophobicContact CG1-CG2 3.91Å; V156-V220 HydrophobicContact CG2-CG2 3.68Å; P184-V220 HydrophobicContact CB-CG1 3.63Å; P184-V220 HydrophobicContact CG-CG1 3.59Å; V186-V220 HydrophobicContact CG2-CG2 4.45Å; V216-V220 HydrophobicContact CG1-CG2 3.99Å; V216-V220 WeakPolarHBondContact O-CG2 3.31Å; V216-V220 PolarHBondContact O-N 2.93Å; L217-V220 PolarHBondContact O-N 3.31Å; V220-K222 VanDerWaalsContact C-N 3.29Å; V220-K222 PolarHBondContact O-N 2.72Å; V220-K223 PolarHBondContact O-N 3.23Å; V220-K223 VanDerWaalsContact O-N 3.17Å; V220-Y224 HydrophobicContact CG1-CD2 3.74Å; V220-Y224 HydrophobicContact CG1-CE2 4.12Å; V220-Y224 WeakPolarHBondContact O-CD2 3.39Å; V220-Y224 PolarHBondContact O-N 3.09Å; V220-V231 HydrophobicContact CG1-CG1 4.11Å; V220-V231 HydrophobicContact CG1-CG2 4Å
221S96.9Very high96.5Very high16 Ų1653.8 Ų53.811%0.11225%0.25CC..Hα-helixtrans-60.4-40.3-178.277.60000111.5L217 E218 Q225 I226L217-S221 WeakPolarHBondContact O-CB 3.22Å; L217-S221 PolarHBondContact O-N 2.89Å; L217-S221 PolarHBondContact O-OG 3.32Å; E218-S221 PolarHBondContact O-OG 3.37Å; S221-Q225 WeakPolarHBondContact O-CA 3.45Å; S221-Q225 PolarHBondContact O-N 3.44Å; S221-I226 CarbonylContact C-O 3.56Å; S221-I226 WeakPolarHBondContact CA-O 3.39Å; S221-I226 WeakPolarHBondContact CB-O 3.3Å; S221-I226 PolarHBondContact O-N 3.09Å; S221-I226 VanDerWaalsContact O-N 3.08Å; S221-I226 VanDerWaalsContact O-O 3.04Å
222K97.5Very high96.5Very high155 Ų15552.4 Ų52.467%0.67424%0.243SC*.Hα-helixtrans-65.9-46.5175-71170.7-173168.70111.9E218 E219 V220 Q225E218-K222 WeakPolarHBondContact O-CD 3.43Å; E218-K222 VanDerWaalsContact O-CG 3.28Å; E218-K222 WeakPolarHBondContact O-CG 3.44Å; E218-K222 PolarHBondContact O-N 3.39Å; E219-K222 PolarHBondContact O-N 3.41Å; V220-K222 VanDerWaalsContact C-N 3.29Å; V220-K222 PolarHBondContact O-N 2.72Å; K222-Q225 PolarHBondContact O-N 2.83Å
223K97.4Very high96.5Very high114 Ų11451.6 Ų51.650%0.49624%0.24SC..Hα-helixtrans-63.3-44-178.5178.7175.3178178.30112.5D120 E219 V220D120-K223 IonicContact OD1-NZ 3.67Å; D120-K223 PolarHBondContact OD1-NZ 2.89Å; D120-K223 WeakPolarHBondContact OD2-CE 3.42Å; D120-K223 IonicContact OD2-NZ 2.67Å; D120-K223 PolarHBondContact OD2-NZ 3.08Å; E219-K223 PolarHBondContact O-N 3.43Å; E219-K223 VanDerWaalsContact O-N 3.08Å; V220-K223 PolarHBondContact O-N 3.23Å; V220-K223 VanDerWaalsContact O-N 3.17Å
224Y95.3Very high96.5Very high47 Ų4751.6 Ų51.618%0.18424%0.24CC..Hα-helixtrans-91.81.5-176.5-70.6-96000113.3D120 G182 P184 V220 I226D120-Y224 PolarHBondContact OD2-OH 3.26Å; G182-Y224 WeakPolarHBondContact O-CE1 3.29Å; P184-Y224 HydrophobicContact CB-CD1 4.28Å; P184-Y224 HydrophobicContact CB-CD2 4.04Å; P184-Y224 HydrophobicContact CB-CE1 4.12Å; P184-Y224 HydrophobicContact CB-CE2 3.9Å; P184-Y224 HydrophobicContact CB-CG 4.24Å; P184-Y224 HydrophobicContact CG-CD1 3.98Å; P184-Y224 HydrophobicContact CG-CD2 3.93Å; P184-Y224 HydrophobicContact CG-CE1 4.33Å; P184-Y224 HydrophobicContact CG-CE2 4.3Å; P184-Y224 HydrophobicContact CG-CG 3.76Å; V220-Y224 HydrophobicContact CG1-CD2 3.74Å; V220-Y224 HydrophobicContact CG1-CE2 4.12Å; V220-Y224 WeakPolarHBondContact O-CD2 3.39Å; V220-Y224 PolarHBondContact O-N 3.09Å; Y224-I226 VanDerWaalsContact C-N 3.29Å; Y224-I226 PolarHBondContact O-N 2.82Å
225Q95.4Very high96.6Very high181 Ų18151.3 Ų51.385%0.84624%0.238SC*.THydrogen-bonded Turntrans54.841.7178.9-57.2176.337.400113.4S221 K222S221-Q225 WeakPolarHBondContact O-CA 3.45Å; S221-Q225 PolarHBondContact O-N 3.44Å; K222-Q225 PolarHBondContact O-N 2.83Å
226I94.1Very high96.6Very high31 Ų3146.6 Ų46.616%0.15922%0.22CC..SBendtrans-126.8169176.956175000109.9P184 S221 Y224 Q230 V231P184-I226 HydrophobicContact CG-CD1 3.81Å; S221-I226 CarbonylContact C-O 3.56Å; S221-I226 WeakPolarHBondContact CA-O 3.39Å; S221-I226 WeakPolarHBondContact CB-O 3.3Å; S221-I226 PolarHBondContact O-N 3.09Å; S221-I226 VanDerWaalsContact O-N 3.08Å; S221-I226 VanDerWaalsContact O-O 3.04Å; Y224-I226 VanDerWaalsContact C-N 3.29Å; Y224-I226 PolarHBondContact O-N 2.82Å; I226-Q230 HydrophobicContact CB-CB 4.19Å; I226-Q230 HydrophobicContact CD1-CB 4.44Å; I226-V231 HydrophobicContact CD1-CG2 3.68Å; I226-V231 HydrophobicContact CG1-CG2 4.16Å
227T93.8Very high96.6Very high70 Ų7046.6 Ų46.643%0.42922%0.22SC..  trans-79.9159.1173.172.80000111.1Q229 Q230T227-Q229 PolarHBondContact O-N 3.43Å; T227-Q230 WeakPolarHBondContact O-CB 3.23Å; T227-Q230 PolarHBondContact O-N 3.02Å; T227-Q230 VanDerWaalsContact OG1-CG 3.28Å; T227-Q230 WeakPolarHBondContact OG1-CG 3.24Å; T227-Q230 PolarHBondContact OG1-N 2.92Å; T227-Q230 PolarHBondContact OG1-OE1 2.94Å
228Q93.6Very high96.6Very high52 Ų5246.5 Ų46.524%0.24322%0.219CC..G310 helixtrans-60.2-37.1177.5-64.8179.121.500112.1L217 Q230 V231L217-Q228 HydrophobicContact CB-CB 4.26Å; L217-Q228 HydrophobicContact CB-CG 4.13Å; Q228-Q230 PolarHBondContact O-N 3.37Å; Q228-V231 PolarHBondContact O-N 3.45Å
229Q91.4Very high96.7Very high92 Ų9242.2 Ų42.243%0.4320%0.199SC..G310 helixtrans-67.2-21.3178.6-6574.118.900112.1T227T227-Q229 PolarHBondContact O-N 3.43Å
230Q94.3Very high96.7Very high43 Ų4339.9 Ų39.920%0.20119%0.189CC..G310 helixtrans-81.4-19.1178.2-74174.4-50.800114.1I226 T227 Q228 P232 T365 Q368I226-Q230 HydrophobicContact CB-CB 4.19Å; I226-Q230 HydrophobicContact CD1-CB 4.44Å; T227-Q230 WeakPolarHBondContact O-CB 3.23Å; T227-Q230 PolarHBondContact O-N 3.02Å; T227-Q230 VanDerWaalsContact OG1-CG 3.28Å; T227-Q230 WeakPolarHBondContact OG1-CG 3.24Å; T227-Q230 PolarHBondContact OG1-N 2.92Å; T227-Q230 PolarHBondContact OG1-OE1 2.94Å; Q228-Q230 PolarHBondContact O-N 3.37Å; Q230-P232 VanDerWaalsContact O-CD 3.28Å; Q230-P232 WeakPolarHBondContact O-CD 2.81Å; Q230-T365 HydrophobicContact CB-CG2 4.24Å; Q230-T365 PolarHBondContact NE2-O 2.84Å; Q230-Q368 VanDerWaalsContact CG-OE1 3.28Å; Q230-Q368 PolarHBondContact O-NE2 3.32Å; Q230-Q368 PolarHBondContact O-OE1 3.48Å
231V96.9Very high96.7Very high1 Ų140.1 Ų40.11%0.00619%0.191CC..SBendtrans-75.2119.8177-175.80000108.8P184 V186 L217 V220 I226 Q228P184-V231 HydrophobicContact CG-CG1 4.26Å; P184-V231 HydrophobicContact CG-CG2 4.43Å; V186-V231 HydrophobicContact CB-CG1 4.46Å; V186-V231 HydrophobicContact CG2-CG1 3.7Å; L217-V231 HydrophobicContact CD2-CB 3.68Å; L217-V231 HydrophobicContact CD2-CG1 3.51Å; L217-V231 HydrophobicContact CD2-CG2 4.19Å; V220-V231 HydrophobicContact CG1-CG1 4.11Å; V220-V231 HydrophobicContact CG1-CG2 4Å; I226-V231 HydrophobicContact CD1-CG2 3.68Å; I226-V231 HydrophobicContact CG1-CG2 4.16Å; Q228-V231 PolarHBondContact O-N 3.45Å
232P97.7Very high96.7Very high4 Ų441.7 Ų41.73%0.02620%0.198CC..  trans-62.4132168.6-18.532.3000111.7P184 L185 V186 Q230 S321 L322 I362P184-P232 VanDerWaalsContact O-CD 3.23Å; P184-P232 WeakPolarHBondContact O-CD 3.44Å; L185-P232 HydrophobicContact CD1-CB 3.74Å; V186-P232 PolarHBondContact N-O 2.89Å; Q230-P232 VanDerWaalsContact O-CD 3.28Å; Q230-P232 WeakPolarHBondContact O-CD 2.81Å; P232-S321 WeakPolarHBondContact CA-OG 3.05Å; P232-L322 HydrophobicContact CB-CD1 4.19Å; P232-L322 HydrophobicContact CB-CD2 3.83Å; P232-L322 HydrophobicContact CB-CG 3.88Å; P232-I362 HydrophobicContact CG-CG2 4.42Å
233V98.6Very high96.6Very high1 Ų135.8 Ų35.81%0.00618%0.175CC..EExtended strand (participates in β ladder)trans-125.6133.7178.3-177.80000110.3V186 V213 L217 I235 A317 T318V186-V233 HydrophobicContact CB-CG2 4.29Å; V186-V233 HydrophobicContact CG1-CG1 4.48Å; V186-V233 CarbonylContact O-C 3.58Å; V186-V233 WeakPolarHBondContact O-CA 3.48Å; V213-V233 HydrophobicContact CG1-CG1 4Å; L217-V233 HydrophobicContact CD1-CG2 4.02Å; L217-V233 HydrophobicContact CD2-CG2 3.78Å; L217-V233 HydrophobicContact CG-CG2 4.36Å; V233-I235 HydrophobicContact CG1-CD1 4.39Å; V233-I235 HydrophobicContact CG1-CG1 3.87Å; V233-A317 WeakPolarHBondContact O-CA 3.45Å; V233-T318 HydrophobicContact CB-CG2 3.83Å; V233-T318 HydrophobicContact CG2-CG2 4.21Å; V233-T318 PolarHBondContact N-OG1 2.97Å; V233-T318 PolarHBondContact O-N 3.34Å; V233-T318 VanDerWaalsContact O-N 3.15Å; V233-T318 PolarHBondContact O-OG1 2.77Å
234L98.6Very high96.5Very high0 Ų035.7 Ų35.70%018%0.181CC..EExtended strand (participates in β ladder)trans-116132.6163.5-72.1171.4000109.5F14 V16 V186 V187 A188 I315 F316 A317 L322 Y360F14-L234 HydrophobicContact CE2-CD1 3.48Å; F14-L234 VanDerWaalsContact CE2-CD1 3.48Å; F14-L234 HydrophobicContact CZ-CD1 3.66Å; V16-L234 HydrophobicContact CB-CD1 4.17Å; V16-L234 HydrophobicContact CG1-CD1 4.24Å; V16-L234 HydrophobicContact CG1-CD2 4.42Å; V16-L234 HydrophobicContact CG2-CD1 4.25Å; V186-L234 PolarHBondContact O-N 2.95Å; V187-L234 HydrophobicContact CG1-CB 4.46Å; V187-L234 HydrophobicContact CG2-CD1 4.43Å; A188-L234 PolarHBondContact N-O 3.34Å; L234-I315 HydrophobicContact CD2-CG2 4.21Å; L234-F316 CarbonylContact C-O 3.51Å; L234-F316 WeakPolarHBondContact CA-O 3.43Å; L234-A317 HydrophobicContact CD2-CB 3.7Å; L234-L322 HydrophobicContact CD2-CD1 3.83Å; L234-L322 HydrophobicContact CG-CD1 3.84Å; L234-Y360 HydrophobicContact CD2-CD2 4.29Å; L234-Y360 HydrophobicContact CD2-CE2 3.87Å
235I98.8Very high96.6Very high0 Ų034.3 Ų34.30%018%0.178CC..EExtended strand (participates in β ladder)trans-124.9109.9170-51.4-174.8000107.4A188 L209 V213 V233 F239 L288 L290 F316A188-I235 HydrophobicContact CB-CG1 4.37Å; A188-I235 HydrophobicContact CB-CG2 4.46Å; A188-I235 WeakPolarHBondContact O-CA 3.47Å; L209-I235 HydrophobicContact CD2-CG2 3.73Å; L209-I235 HydrophobicContact CG-CG2 4.39Å; V213-I235 HydrophobicContact CG1-CD1 4.47Å; V213-I235 HydrophobicContact CG2-CD1 4.24Å; V233-I235 HydrophobicContact CG1-CD1 4.39Å; V233-I235 HydrophobicContact CG1-CG1 3.87Å; I235-F239 HydrophobicContact CG2-CZ 4Å; I235-L288 HydrophobicContact CD1-CD1 4.02Å; I235-L290 HydrophobicContact CD1-CD1 3.89Å; I235-L290 HydrophobicContact CD1-CD2 4.39Å; I235-F316 HydrophobicContact CB-CB 4.29Å; I235-F316 PolarHBondContact N-O 3.44Å; I235-F316 PolarHBondContact O-N 3.45Å
236C98.7Very high96.7Very high0 Ų025.7 Ų25.70%014%0.137CC..EExtended strand (participates in β ladder)trans-110.2162.8-179.2-53.50000110.4C18 T62 A188 T189 A190 Y314C18-C236 HydrophobicContact CB-CB 3.97Å; T62-C236 HydrophobicContact CG2-CB 3.96Å; T62-C236 WeakPolarHBondContact OG1-CB 3.13Å; A188-C236 PolarHBondContact O-N 3.35Å; T189-C236 CarbonylContact C-O 3.56Å; T189-C236 WeakPolarHBondContact CA-O 3.44Å; T189-C236 PolarHBondContact OG1-O 2.64Å; A190-C236 PolarHBondContact N-O 2.8Å; A190-C236 VanDerWaalsContact N-O 3.1Å; C236-Y314 CarbonylContact C-O 3.28Å; C236-Y314 VanDerWaalsContact CA-O 3.25Å; C236-Y314 WeakPolarHBondContact CA-O 3.33Å
237G98.3Very high96.9Very high0 Ų024.3 Ų24.30%013%0.131CC..EExtended strand (participates in β ladder)trans148.3-178.6163.700000114.7C18 A190 F239 D313 Y314C18-G237 VanDerWaalsContact SG-CA 3.54Å; C18-G237 PolarHBondContact SG-N 3.08Å; A190-G237 VanDerWaalsContact O-CA 3.28Å; A190-G237 WeakPolarHBondContact O-CA 3.33Å; G237-F239 WeakPolarHBondContact O-CD2 3.39Å; G237-D313 VanDerWaalsContact O-CA 3.31Å; G237-D313 WeakPolarHBondContact O-CA 3.41Å; G237-Y314 PolarHBondContact N-O 3.03Å; G237-Y314 PolarHBondContact O-N 3.2Å
238D98.7Very high97Very high1 Ų122.9 Ų22.91%0.00512%0.118CC..EExtended strand (participates in β ladder)trans-89.1109.1169.1-176.7-8.9000108.6N20 Q64 A190 H191 I192 N240 D313 H353N20-D238 PolarHBondContact ND2-OD2 2.79Å; Q64-D238 HydrophobicContact CG-CB 4.29Å; A190-D238 PolarHBondContact O-N 3.4Å; H191-D238 WeakPolarHBondContact CA-O 3.43Å; H191-D238 IonicContact CD2-OD2 3.8Å; H191-D238 IonicContact NE2-OD2 3.51Å; I192-D238 PolarHBondContact N-O 3.45Å; D238-N240 VanDerWaalsContact OD1-CG 3.3Å; D238-N240 PolarHBondContact OD1-N 3.29Å; D238-N240 PolarHBondContact OD1-ND2 3.24Å; D238-D313 WeakPolarHBondContact CB-OD1 3.43Å; D238-H353 IonicContact OD2-CE1 3.72Å; D238-H353 PolarHBondContact OD2-CE1 3.12Å; D238-H353 IonicContact OD2-NE2 3.83Å
239F98.6Very high97.2Very high0 Ų022.9 Ų22.90%012%0.118CC..  trans-93.9-6.2-179.9-74.5-97.1000112.6I192 L209 I235 G237 S241 V247 L251 I312 Y314 F316I192-F239 HydrophobicContact CG1-CB 4.47Å; I192-F239 HydrophobicContact CG1-CD1 3.81Å; I192-F239 HydrophobicContact CG1-CE1 4.35Å; I192-F239 HydrophobicContact CG1-CG 4.3Å; L209-F239 HydrophobicContact CD2-CE1 3.99Å; L209-F239 HydrophobicContact CD2-CZ 4.12Å; I235-F239 HydrophobicContact CG2-CZ 4Å; G237-F239 WeakPolarHBondContact O-CD2 3.39Å; F239-S241 WeakPolarHBondContact O-CB 3.35Å; F239-S241 PolarHBondContact O-N 3.44Å; F239-S241 PolarHBondContact O-OG 3.48Å; F239-V247 HydrophobicContact CB-CG1 4.29Å; F239-V247 HydrophobicContact CD1-CG1 3.85Å; F239-V247 HydrophobicContact CG-CG1 4.45Å; F239-L251 HydrophobicContact CD1-CD1 3.81Å; F239-L251 HydrophobicContact CE1-CD1 3.44Å; F239-L251 VanDerWaalsContact CE1-CD1 3.44Å; F239-L251 HydrophobicContact CZ-CD1 4.03Å; F239-I312 PolarHBondContact N-O 2.99Å; F239-Y314 HydrophobicContact CB-CD2 3.96Å; F239-Y314 HydrophobicContact CB-CE2 4.12Å; F239-Y314 AromaticContact CD2-CD2 3.71Å; F239-Y314 HydrophobicContact CD2-CD2 3.71Å; F239-Y314 HydrophobicContact CD2-CG 4.45Å; F239-Y314 HydrophobicContact CG-CD2 4.07Å; F239-F316 HydrophobicContact CE2-CD2 4.43Å; F239-F316 HydrophobicContact CE2-CE2 4.47Å; F239-F316 HydrophobicContact CZ-CD2 4.43Å
240N98.4Very high97.5Very high25 Ų2518.5 Ų18.513%0.13410%0.098CC..  trans48.432.5-176.7-80.6-68.5000113.2I192 H193 K202 D238I192-N240 PolarHBondContact O-ND2 2.88Å; H193-N240 VanDerWaalsContact O-CB 3.31Å; H193-N240 WeakPolarHBondContact O-CB 3.34Å; K202-N240 HydrophobicContact CD-CB 4.4Å; K202-N240 WeakPolarHBondContact CD-O 3.37Å; K202-N240 WeakPolarHBondContact CE-O 3.25Å; K202-N240 PolarHBondContact NZ-O 3.5Å; D238-N240 VanDerWaalsContact OD1-CG 3.3Å; D238-N240 PolarHBondContact OD1-N 3.29Å; D238-N240 PolarHBondContact OD1-ND2 3.24Å
241S97.9Very high97.7Very high9 Ų916.5 Ų16.56%0.0639%0.088CC..  trans-141.2128.2-169.4-59.20000110.6F239 S245 V247 Y314F239-S241 WeakPolarHBondContact O-CB 3.35Å; F239-S241 PolarHBondContact O-N 3.44Å; F239-S241 PolarHBondContact O-OG 3.48Å; S241-S245 WeakPolarHBondContact CB-OG 3.48Å; S241-V247 WeakPolarHBondContact OG-CG2 3.46Å; S241-Y314 WeakPolarHBondContact O-CE2 3.39Å; S241-Y314 PolarHBondContact O-OH 3Å
242L97.1Very high97.6Very high50 Ų5018.3 Ų18.326%0.26210%0.101SC..  trans-72162.9-179.6-69.6172.3000112.6D244 S245 F308 I312 Y314L242-D244 VanDerWaalsContact CB-OD1 3.25Å; L242-D244 WeakPolarHBondContact CB-OD1 3.4Å; L242-D244 PolarHBondContact O-N 3.48Å; L242-D244 VanDerWaalsContact O-N 3.14Å; L242-S245 WeakPolarHBondContact O-CB 3.08Å; L242-S245 PolarHBondContact O-N 3.06Å; L242-S245 PolarHBondContact O-OG 2.71Å; L242-F308 HydrophobicContact CD2-CE2 4.28Å; L242-F308 HydrophobicContact CD2-CZ 3.89Å; L242-F308 HydrophobicContact CG-CZ 4.47Å; L242-I312 HydrophobicContact CD2-CG2 4.3Å; L242-Y314 VanDerWaalsContact C-OH 3.24Å
243P95.8Very high97.5Very high30 Ų3024.4 Ų24.420%0.19513%0.127CC..THydrogen-bonded Turntrans-63-18.4-179-26.336.7000115.3F248 I296 M311 Y314P243-F248 WeakPolarHBondContact O-CD1 3.48Å; P243-I296 HydrophobicContact CG-CD1 4.35Å; P243-M311 HydrophobicContact CG-CB 4.07Å; P243-M311 HydrophobicContact CG-CG 4.33Å; P243-M311 HydrophobicContact CG-SD 4.02Å; P243-Y314 WeakPolarHBondContact CD-OH 3.33Å; P243-Y314 HydrophobicContact CG-CE1 4.49Å
244D94.2Very high97.4Very high113 Ų11324.9 Ų24.960%0.60413%0.133SC*.THydrogen-bonded Turntrans-92.54.1175.364.9-21.5000113.7L242L242-D244 VanDerWaalsContact CB-OD1 3.25Å; L242-D244 WeakPolarHBondContact CB-OD1 3.4Å; L242-D244 PolarHBondContact O-N 3.48Å; L242-D244 VanDerWaalsContact O-N 3.14Å
245S97.1Very high97.3Very high17 Ų1729.8 Ų29.812%0.11916%0.156CC..SBendtrans-77.5160.4177.969.20000113.5S241 L242 V247 F248 E249S241-S245 WeakPolarHBondContact CB-OG 3.48Å; L242-S245 WeakPolarHBondContact O-CB 3.08Å; L242-S245 PolarHBondContact O-N 3.06Å; L242-S245 PolarHBondContact O-OG 2.71Å; S245-V247 PolarHBondContact O-N 3.08Å; S245-F248 PolarHBondContact O-N 2.93Å; S245-F248 PolarHBondContact OG-N 2.92Å; S245-E249 PolarHBondContact O-N 3.39Å
246G97.8Very high97.2Very high0 Ų030 Ų300%016%0.156CC..Hα-helixtrans-63.2-27.6170.900000113.4L203 Y250 I256 H260 D262L203-G246 WeakPolarHBondContact CD1-O 3.37Å; G246-Y250 WeakPolarHBondContact O-CB 3.43Å; G246-Y250 PolarHBondContact O-N 3.42Å; G246-I256 WeakPolarHBondContact O-CD1 3.31Å; G246-H260 WeakPolarHBondContact CA-CE1 3.38Å; G246-D262 WeakPolarHBondContact CA-OD2 2.82Å; G246-D262 PolarHBondContact N-OD2 2.68Å
247V98.1Very high97.1Very high3 Ų332.3 Ų32.32%0.01817%0.171CC..Hα-helixtrans-62.3-52.5173.8168.50000110.2K202 L203 S206 F239 S241 S245 Y250 L251K202-V247 HydrophobicContact CB-CG2 3.91Å; L203-V247 HydrophobicContact CB-CG2 4.07Å; L203-V247 HydrophobicContact CD1-CG2 4.41Å; S206-V247 WeakPolarHBondContact OG-CG1 3.19Å; F239-V247 HydrophobicContact CB-CG1 4.29Å; F239-V247 HydrophobicContact CD1-CG1 3.85Å; F239-V247 HydrophobicContact CG-CG1 4.45Å; S241-V247 WeakPolarHBondContact OG-CG2 3.46Å; S245-V247 PolarHBondContact O-N 3.08Å; V247-Y250 PolarHBondContact O-N 3.02Å; V247-L251 HydrophobicContact CG1-CD1 3.89Å; V247-L251 VanDerWaalsContact O-CG 3.31Å; V247-L251 WeakPolarHBondContact O-CG 3.27Å; V247-L251 PolarHBondContact O-N 2.94Å
248F97.1Very high96.9Very high39 Ų3933.6 Ų33.617%0.17118%0.176CC..Hα-helixtrans-65.6-43-180-171.1-88.5000111.2P243 S245 Y250 L251 S252 Y314 F316P243-F248 WeakPolarHBondContact O-CD1 3.48Å; S245-F248 PolarHBondContact O-N 2.93Å; S245-F248 PolarHBondContact OG-N 2.92Å; F248-Y250 PolarHBondContact O-N 2.99Å; F248-L251 PolarHBondContact O-N 2.9Å; F248-S252 VanDerWaalsContact O-CB 3.27Å; F248-S252 WeakPolarHBondContact O-CB 3.14Å; F248-S252 PolarHBondContact O-N 3.45Å; F248-S252 PolarHBondContact O-OG 2.91Å; F248-Y314 AromaticContact CD2-CD1 3.86Å; F248-Y314 HydrophobicContact CD2-CD1 3.86Å; F248-Y314 AromaticContact CD2-CE1 3.36Å; F248-Y314 HydrophobicContact CD2-CE1 3.36Å; F248-Y314 HydrophobicContact CD2-CE2 4.46Å; F248-Y314 AromaticContact CD2-CZ 3.72Å; F248-Y314 AromaticContact CE2-CD1 3.67Å; F248-Y314 HydrophobicContact CE2-CD1 3.67Å; F248-Y314 AromaticContact CE2-CE1 3.4Å; F248-Y314 HydrophobicContact CE2-CE1 3.4Å; F248-Y314 VanDerWaalsContact CE2-CE1 3.4Å; F248-F316 AromaticContact CD2-CZ 3.8Å; F248-F316 HydrophobicContact CD2-CZ 3.8Å; F248-F316 HydrophobicContact CE2-CE1 4.2Å; F248-F316 AromaticContact CE2-CZ 3.81Å; F248-F316 HydrophobicContact CE2-CZ 3.81Å
249E97.3Very high96.7Very high53 Ų5342.3 Ų42.325%0.24821%0.209CC..Hα-helixtrans-56.7-50.6175.2175.5167.9-161.700111.7S245 S252 K253 I256 H260S245-E249 PolarHBondContact O-N 3.39Å; E249-S252 PolarHBondContact O-OG 3.35Å; E249-K253 HydrophobicContact CG-CD 3.8Å; E249-K253 HydrophobicContact CG-CG 4.31Å; E249-K253 VanDerWaalsContact O-CB 3.28Å; E249-K253 WeakPolarHBondContact O-CB 3.44Å; E249-K253 WeakPolarHBondContact O-CG 3.31Å; E249-K253 PolarHBondContact O-N 2.93Å; E249-K253 IonicContact OE1-NZ 3.4Å; E249-K253 PolarHBondContact OE1-NZ 3.23Å; E249-I256 HydrophobicContact CG-CG1 4.48Å; E249-H260 IonicContact OE2-CD2 3.7Å; E249-H260 PolarHBondContact OE2-CD2 3Å; E249-H260 IonicContact OE2-NE2 2.72Å; E249-H260 PolarHBondContact OE2-NE2 2.94Å
250Y98.1Very high96.6Very high0 Ų043.7 Ų43.70%022%0.215CC..Hα-helixtrans-58.5-52.2-179.2171.5-106.8000111.3L203 M207 T210 G246 V247 F248 G254 Q255 I256 I284 H286L203-Y250 HydrophobicContact CD1-CD1 4.47Å; L203-Y250 HydrophobicContact CD1-CG 4.23Å; M207-Y250 HydrophobicContact CB-CE1 4.33Å; M207-Y250 HydrophobicContact CE-CD2 4.34Å; M207-Y250 HydrophobicContact CE-CE2 4.38Å; M207-Y250 HydrophobicContact CG-CD1 4.34Å; M207-Y250 HydrophobicContact CG-CE1 3.8Å; M207-Y250 HydrophobicContact CG-CE2 4.09Å; T210-Y250 HydrophobicContact CG2-CE1 3.94Å; T210-Y250 PolarHBondContact OG1-OH 3.02Å; G246-Y250 WeakPolarHBondContact O-CB 3.43Å; G246-Y250 PolarHBondContact O-N 3.42Å; V247-Y250 PolarHBondContact O-N 3.02Å; F248-Y250 PolarHBondContact O-N 2.99Å; Y250-G254 CarbonylContact O-C 3.55Å; Y250-G254 WeakPolarHBondContact O-CA 3.22Å; Y250-G254 PolarHBondContact O-N 3.17Å; Y250-Q255 PolarHBondContact O-N 3.46Å; Y250-I256 HydrophobicContact CD2-CB 4.15Å; Y250-I256 HydrophobicContact CD2-CG2 3.78Å; Y250-I256 HydrophobicContact CG-CG2 4.43Å; Y250-I284 HydrophobicContact CE2-CG2 4.07Å; Y250-H286 AromaticContact CE1-CD2 3.54Å; Y250-H286 AromaticContact CE2-CD2 3.63Å; Y250-H286 AromaticContact CZ-CD2 3.33Å; Y250-H286 PolarHBondContact O-NE2 3.27Å
251L97.6Very high96.5Very high0 Ų048.6 Ų48.60%024%0.239CC..Hα-helixtrans-63.3-45.2-177.5-68.5171.3000112.2T210 F239 V247 F248 H286 L290 F316T210-L251 HydrophobicContact CG2-CD2 3.5Å; F239-L251 HydrophobicContact CD1-CD1 3.81Å; F239-L251 HydrophobicContact CE1-CD1 3.44Å; F239-L251 VanDerWaalsContact CE1-CD1 3.44Å; F239-L251 HydrophobicContact CZ-CD1 4.03Å; V247-L251 HydrophobicContact CG1-CD1 3.89Å; V247-L251 VanDerWaalsContact O-CG 3.31Å; V247-L251 WeakPolarHBondContact O-CG 3.27Å; V247-L251 PolarHBondContact O-N 2.94Å; F248-L251 PolarHBondContact O-N 2.9Å; L251-H286 WeakPolarHBondContact CA-NE2 3.46Å; L251-H286 PolarHBondContact O-CE1 3.03Å; L251-H286 PolarHBondContact O-NE2 3.1Å; L251-L290 HydrophobicContact CD2-CD1 4.2Å; L251-L290 WeakPolarHBondContact O-CB 3.43Å; L251-F316 HydrophobicContact CB-CE1 4.03Å; L251-F316 HydrophobicContact CB-CE2 4.19Å; L251-F316 HydrophobicContact CB-CZ 3.86Å; L251-F316 HydrophobicContact CD1-CD2 4.21Å; L251-F316 HydrophobicContact CD1-CE2 3.65Å; L251-F316 HydrophobicContact CD1-CZ 4.07Å
252S95.7Very high96.5Very high39 Ų3949.4 Ų49.427%0.27324%0.242SC..Hα-helixtrans-76.3-42-175.660.90000113.4F248 E249 G254F248-S252 VanDerWaalsContact O-CB 3.27Å; F248-S252 WeakPolarHBondContact O-CB 3.14Å; F248-S252 PolarHBondContact O-N 3.45Å; F248-S252 PolarHBondContact O-OG 2.91Å; E249-S252 PolarHBondContact O-OG 3.35Å; S252-G254 VanDerWaalsContact C-N 3.35Å
253K95.8Very high96.4Very high132 Ų13247 Ų4757%0.57423%0.23SC*.Hα-helixtrans-84.1-12.3-179.4-60.4-171.8-168.2165.70112.9E249 Q255E249-K253 HydrophobicContact CG-CD 3.8Å; E249-K253 HydrophobicContact CG-CG 4.31Å; E249-K253 VanDerWaalsContact O-CB 3.28Å; E249-K253 WeakPolarHBondContact O-CB 3.44Å; E249-K253 WeakPolarHBondContact O-CG 3.31Å; E249-K253 PolarHBondContact O-N 2.93Å; E249-K253 IonicContact OE1-NZ 3.4Å; E249-K253 PolarHBondContact OE1-NZ 3.23Å; K253-Q255 PolarHBondContact O-N 3.2Å
254G96.3Very high96.4Very high12 Ų1249.2 Ų49.212%0.12424%0.236CC..SBendtrans75.51.5-173.500000113.7Y250 S252 S285 H286Y250-G254 CarbonylContact O-C 3.55Å; Y250-G254 WeakPolarHBondContact O-CA 3.22Å; Y250-G254 PolarHBondContact O-N 3.17Å; S252-G254 VanDerWaalsContact C-N 3.35Å; G254-S285 CarbonylContact O-C 3.5Å; G254-S285 WeakPolarHBondContact O-CA 3.31Å; G254-S285 VanDerWaalsContact O-CB 3.3Å; G254-S285 WeakPolarHBondContact O-CB 3.48Å; G254-H286 WeakPolarHBondContact CA-NE2 3.5Å; G254-H286 PolarHBondContact O-N 3.14Å
255Q96.6Very high96.4Very high103 Ų10346.4 Ų46.448%0.48123%0.226SC..EExtended strand (participates in β ladder)trans-160.6156.3-175.666.5179.216.100112.5Y250 K253 V283 I284Y250-Q255 PolarHBondContact O-N 3.46Å; K253-Q255 PolarHBondContact O-N 3.2Å; Q255-V283 HydrophobicContact CB-CG1 3.75Å; Q255-V283 HydrophobicContact CG-CG1 4.42Å; Q255-I284 CarbonylContact C-O 3.5Å; Q255-I284 VanDerWaalsContact CA-O 3.23Å; Q255-I284 WeakPolarHBondContact CA-O 3.48Å
256I96.6Very high96.3Very high3 Ų345.6 Ų45.62%0.01522%0.22CC..EExtended strand (participates in β ladder)trans-144.1149.1172.3-159.9175000110.2L203 M207 G246 E249 Y250 H260 V283 I284L203-I256 HydrophobicContact CD1-CD1 4.32Å; L203-I256 HydrophobicContact CD2-CD1 3.84Å; M207-I256 HydrophobicContact CE-CG2 3.76Å; G246-I256 WeakPolarHBondContact O-CD1 3.31Å; E249-I256 HydrophobicContact CG-CG1 4.48Å; Y250-I256 HydrophobicContact CD2-CB 4.15Å; Y250-I256 HydrophobicContact CD2-CG2 3.78Å; Y250-I256 HydrophobicContact CG-CG2 4.43Å; I256-H260 HydrophobicContact CD1-CB 3.72Å; I256-H260 HydrophobicContact CG1-CB 3.84Å; I256-V283 WeakPolarHBondContact O-CA 3.3Å; I256-I284 HydrophobicContact CG2-CB 4.17Å; I256-I284 PolarHBondContact N-O 3.1Å; I256-I284 PolarHBondContact O-N 2.78Å
257T96.1Very high96.1Very high50 Ų5049 Ų4931%0.30723%0.233SC..EExtended strand (participates in β ladder)trans-74.2142.5174.7-179.90000111.2R259 H260 N282T257-R259 HydrophobicContact CG2-CB 4.48Å; T257-R259 PolarHBondContact O-N 3.26Å; T257-R259 VanDerWaalsContact O-N 3.11Å; T257-R259 PolarHBondContact OG1-N 2.7Å; T257-H260 HydrophobicContact CG2-CB 4.2Å; T257-H260 VanDerWaalsContact O-CB 3.22Å; T257-H260 WeakPolarHBondContact O-CB 3.43Å; T257-H260 PolarHBondContact O-N 3.21Å; T257-N282 PolarHBondContact OG1-O 2.99Å
258R94.2Very high95.7Very high27 Ų2756.3 Ų56.310%0.10227%0.272CS..THydrogen-bonded Turntrans-58.5-20.3170.3-77.9-161.9178.2-106.9-7.6114H260 R267 D269 K281 N282 I284R258-H260 PolarHBondContact O-N 2.83Å; R258-R267 VanDerWaalsContact O-CB 3.27Å; R258-R267 WeakPolarHBondContact O-CB 3.3Å; R258-R267 WeakPolarHBondContact O-CG 3.36Å; R258-D269 PolarHBondContact NH1-O 3.32Å; R258-K281 WeakPolarHBondContact CD-O 3.48Å; R258-K281 PolarHBondContact NE-O 3.19Å; R258-N282 PolarHBondContact N-O 3.24Å; R258-I284 HydrophobicContact CG-CD1 4.03Å; R258-I284 HydrophobicContact CG-CG1 4.06Å
259R94.4Very high95.5Very high183 Ų18355.5 Ų55.569%0.69127%0.269SS*.THydrogen-bonded Turntrans-842.6177-66-172.1-69.4-114.80.5113.3T257T257-R259 HydrophobicContact CG2-CB 4.48Å; T257-R259 PolarHBondContact O-N 3.26Å; T257-R259 VanDerWaalsContact O-N 3.11Å; T257-R259 PolarHBondContact OG1-N 2.7Å
260H96.8Very high95.2Very high29 Ų2956.7 Ų56.713%0.13428%0.283CS..  trans-61140.7-175.9-169-82.2000111.5G246 E249 I256 T257 R258 D262 L263 R267G246-H260 WeakPolarHBondContact CA-CE1 3.38Å; E249-H260 IonicContact OE2-CD2 3.7Å; E249-H260 PolarHBondContact OE2-CD2 3Å; E249-H260 IonicContact OE2-NE2 2.72Å; E249-H260 PolarHBondContact OE2-NE2 2.94Å; I256-H260 HydrophobicContact CD1-CB 3.72Å; I256-H260 HydrophobicContact CG1-CB 3.84Å; T257-H260 HydrophobicContact CG2-CB 4.2Å; T257-H260 VanDerWaalsContact O-CB 3.22Å; T257-H260 WeakPolarHBondContact O-CB 3.43Å; T257-H260 PolarHBondContact O-N 3.21Å; R258-H260 PolarHBondContact O-N 2.83Å; H260-D262 VanDerWaalsContact C-N 3.33Å; H260-D262 IonicContact CE1-OD1 3.45Å; H260-D262 PolarHBondContact CE1-OD1 2.67Å; H260-D262 IonicContact CE1-OD2 3.46Å; H260-D262 WeakPolarHBondContact ND1-CB 3.31Å; H260-D262 PolarHBondContact ND1-N 2.95Å; H260-D262 VanDerWaalsContact ND1-N 3.14Å; H260-D262 IonicContact ND1-OD1 2.74Å; H260-D262 PolarHBondContact O-N 3.26Å; H260-L263 HydrophobicContact CB-CD1 4.33Å; H260-L263 PolarHBondContact O-N 3.35Å; H260-R267 PolarHBondContact O-NE 2.59Å
261M96.6Very high94.9Very high129 Ų12956.8 Ų56.864%0.63528%0.284SS*.G310 helixtrans-63.6-41.6-169.7-71.1-59.9-67.400112.4L263 K264 R267M261-L263 PolarHBondContact O-N 3.48Å; M261-L263 VanDerWaalsContact O-N 3.11Å; M261-K264 PolarHBondContact O-N 2.7Å; M261-R267 PolarHBondContact O-NH2 3.45Å; M261-R267 PolarHBondContact SD-NH2 2.97Å
262D96.8Very high94.7Very high26 Ų2656.8 Ų56.814%0.13928%0.284CS..G310 helixtrans-62.3-19.2-179.8-61.313.9000114C199 D200 L203 G246 H260 K264C199-D262 HydrophobicContact CB-CB 4.07Å; D200-D262 WeakPolarHBondContact CA-O 3.29Å; D200-D262 WeakPolarHBondContact CB-O 3.47Å; D200-D262 PolarHBondContact N-O 2.88Å; D200-D262 VanDerWaalsContact N-O 3.12Å; L203-D262 HydrophobicContact CD2-CB 4.2Å; G246-D262 WeakPolarHBondContact CA-OD2 2.82Å; G246-D262 PolarHBondContact N-OD2 2.68Å; H260-D262 VanDerWaalsContact C-N 3.33Å; H260-D262 IonicContact CE1-OD1 3.45Å; H260-D262 PolarHBondContact CE1-OD1 2.67Å; H260-D262 IonicContact CE1-OD2 3.46Å; H260-D262 WeakPolarHBondContact ND1-CB 3.31Å; H260-D262 PolarHBondContact ND1-N 2.95Å; H260-D262 VanDerWaalsContact ND1-N 3.14Å; H260-D262 IonicContact ND1-OD1 2.74Å; H260-D262 PolarHBondContact O-N 3.26Å; D262-K264 PolarHBondContact O-N 2.87Å
263L96.4Very high94.4Very high0 Ų059.5 Ų59.50%029%0.292CS..G310 helixtrans-70.5-14.6175.5-74.4172.3000113L203 M207 H260 M261 S265 F266 R267 L272 I284L203-L263 HydrophobicContact CD2-CD2 3.51Å; L203-L263 HydrophobicContact CD2-CG 3.7Å; L203-L263 HydrophobicContact CG-CD2 4.05Å; M207-L263 HydrophobicContact CE-CD2 4.06Å; H260-L263 HydrophobicContact CB-CD1 4.33Å; H260-L263 PolarHBondContact O-N 3.35Å; M261-L263 PolarHBondContact O-N 3.48Å; M261-L263 VanDerWaalsContact O-N 3.11Å; L263-S265 PolarHBondContact O-N 3.48Å; L263-S265 VanDerWaalsContact O-N 3.13Å; L263-F266 HydrophobicContact CB-CB 4.47Å; L263-F266 HydrophobicContact CD2-CB 4.4Å; L263-F266 WeakPolarHBondContact O-CA 3.48Å; L263-F266 VanDerWaalsContact O-CB 3.25Å; L263-F266 WeakPolarHBondContact O-CB 3.5Å; L263-F266 PolarHBondContact O-N 2.82Å; L263-R267 HydrophobicContact CB-CG 3.63Å; L263-L272 HydrophobicContact CD1-CD1 4.45Å; L263-L272 HydrophobicContact CD2-CD1 3.76Å; L263-I284 HydrophobicContact CD1-CD1 4.19Å
264K95.7Very high94.2Very high76 Ų7657.5 Ų57.533%0.3328%0.284SS..G310 helixtrans43.7-118.1-179.5-63.3-173.2173.31790112.5E197 C199 D200 M261 D262 F266 R267E197-K264 PolarHBondContact O-NZ 2.95Å; C199-K264 WeakPolarHBondContact SG-CE 3.35Å; D200-K264 HydrophobicContact CB-CB 4.13Å; D200-K264 HydrophobicContact CB-CD 4.32Å; D200-K264 HydrophobicContact CB-CG 4.22Å; M261-K264 PolarHBondContact O-N 2.7Å; D262-K264 PolarHBondContact O-N 2.87Å; K264-F266 VanDerWaalsContact C-N 3.28Å; K264-F266 PolarHBondContact O-N 3.42Å; K264-R267 VanDerWaalsContact O-CG 3.28Å; K264-R267 WeakPolarHBondContact O-CG 3.46Å
265S93.7Very high93.9Very high54 Ų5457 Ų5738%0.37828%0.278SS..G310 helixtrans-75.7-11.5-179.953.80000114N140 L263 R267N140-S265 PolarHBondContact ND2-O 3.49Å; N140-S265 WeakPolarHBondContact OD1-CB 3.16Å; N140-S265 PolarHBondContact OD1-OG 2.73Å; L263-S265 PolarHBondContact O-N 3.48Å; L263-S265 VanDerWaalsContact O-N 3.13Å; S265-R267 VanDerWaalsContact C-N 3.28Å; S265-R267 PolarHBondContact O-N 3.06Å
266F94.8Very high93.6Very high0 Ų053.5 Ų53.50%026%0.264CS..G310 helixtrans-77.2-9.6176.2-70.2-82.2000114.3N140 M141 V145 D200 V204 L263 K264 D268 D269 L272N140-F266 HydrophobicContact CB-CD1 3.75Å; N140-F266 HydrophobicContact CB-CD2 4.37Å; N140-F266 HydrophobicContact CB-CE1 3.19Å; N140-F266 HydrophobicContact CB-CE2 3.95Å; N140-F266 HydrophobicContact CB-CG 4.3Å; N140-F266 HydrophobicContact CB-CZ 3.34Å; M141-F266 HydrophobicContact CE-CD1 4.08Å; M141-F266 HydrophobicContact CE-CE1 3.08Å; M141-F266 HydrophobicContact CE-CE2 4.38Å; M141-F266 HydrophobicContact CE-CZ 3.25Å; M141-F266 HydrophobicContact CG-CE1 4.06Å; M141-F266 HydrophobicContact SD-CE1 4.42Å; V145-F266 HydrophobicContact CG2-CE2 4.43Å; V145-F266 HydrophobicContact CG2-CZ 3.93Å; D200-F266 HydrophobicContact CB-CD2 3.92Å; D200-F266 HydrophobicContact CB-CE2 4.19Å; D200-F266 WeakPolarHBondContact OD2-CE2 3.5Å; V204-F266 HydrophobicContact CG2-CD1 4.39Å; V204-F266 HydrophobicContact CG2-CD2 4.26Å; V204-F266 HydrophobicContact CG2-CE2 4.37Å; V204-F266 HydrophobicContact CG2-CG 4.24Å; L263-F266 HydrophobicContact CB-CB 4.47Å; L263-F266 HydrophobicContact CD2-CB 4.4Å; L263-F266 WeakPolarHBondContact O-CA 3.48Å; L263-F266 VanDerWaalsContact O-CB 3.25Å; L263-F266 WeakPolarHBondContact O-CB 3.5Å; L263-F266 PolarHBondContact O-N 2.82Å; K264-F266 VanDerWaalsContact C-N 3.28Å; K264-F266 PolarHBondContact O-N 3.42Å; F266-D268 PolarHBondContact O-N 3.32Å; F266-D269 HydrophobicContact CB-CB 4.47Å; F266-D269 HydrophobicContact CD1-CB 4.18Å; F266-D269 PolarHBondContact O-N 2.98Å; F266-D269 VanDerWaalsContact O-N 3.08Å; F266-L272 HydrophobicContact CB-CD1 3.89Å; F266-L272 HydrophobicContact CB-CG 4.42Å; F266-L272 HydrophobicContact CD1-CD2 4.23Å
267R94.2Very high93.1Very high71 Ų7157.9 Ų57.927%0.26829%0.287SS..G310 helixtrans-56.4-40179.2-63.2-177.3-164.8155.320.2112R258 H260 M261 L263 K264 S265R258-R267 VanDerWaalsContact O-CB 3.27Å; R258-R267 WeakPolarHBondContact O-CB 3.3Å; R258-R267 WeakPolarHBondContact O-CG 3.36Å; H260-R267 PolarHBondContact O-NE 2.59Å; M261-R267 PolarHBondContact O-NH2 3.45Å; M261-R267 PolarHBondContact SD-NH2 2.97Å; L263-R267 HydrophobicContact CB-CG 3.63Å; K264-R267 VanDerWaalsContact O-CG 3.28Å; K264-R267 WeakPolarHBondContact O-CG 3.46Å; S265-R267 VanDerWaalsContact C-N 3.28Å; S265-R267 PolarHBondContact O-N 3.06Å
268D89.8Confident92.6Very high157 Ų15757.2 Ų57.284%0.8429%0.285SS*.G310 helixtrans-95.21.2-178.6-55.6-47.8000112.6F266F266-D268 PolarHBondContact O-N 3.32Å
269D91.3Very high92.1Very high21 Ų2163 Ų6311%0.11232%0.323CS..  trans-88.8119.2-176.2-160-40.2000111S138 N140 R258 F266 C271S138-D269 WeakPolarHBondContact CB-OD2 3.39Å; S138-D269 PolarHBondContact OG-OD2 3.2Å; N140-D269 PolarHBondContact ND2-OD2 3.03Å; R258-D269 PolarHBondContact NH1-O 3.32Å; F266-D269 HydrophobicContact CB-CB 4.47Å; F266-D269 HydrophobicContact CD1-CB 4.18Å; F266-D269 PolarHBondContact O-N 2.98Å; F266-D269 VanDerWaalsContact O-N 3.08Å; D269-C271 PolarHBondContact O-N 2.91Å; D269-C271 VanDerWaalsContact OD1-CB 3.24Å; D269-C271 WeakPolarHBondContact OD1-CB 3.4Å; D269-C271 PolarHBondContact OD1-N 3.39Å; D269-C271 PolarHBondContact OD1-SG 3.32Å
270S91.6Very high91.9Very high78 Ų7857.8 Ų57.855%0.54531%0.309SS..G310 helixtrans-68.5-14.317961.40000112.6L272 E273S270-L272 PolarHBondContact O-N 3.42Å; S270-L272 VanDerWaalsContact O-N 3.12Å; S270-E273 VanDerWaalsContact O-CB 3.26Å; S270-E273 WeakPolarHBondContact O-CB 3.22Å; S270-E273 WeakPolarHBondContact O-CG 3.23Å; S270-E273 PolarHBondContact O-N 2.97Å
271C92.3Very high91.3Very high2 Ų263.6 Ų63.61%0.01433%0.334CS..G310 helixtrans-59.5-28.1179.474.10000113.6A135 M141 D269 E273 K274A135-C271 HydrophobicContact CB-CB 3.72Å; M141-C271 HydrophobicContact CG-CB 4.5Å; D269-C271 PolarHBondContact O-N 2.91Å; D269-C271 VanDerWaalsContact OD1-CB 3.24Å; D269-C271 WeakPolarHBondContact OD1-CB 3.4Å; D269-C271 PolarHBondContact OD1-N 3.39Å; D269-C271 PolarHBondContact OD1-SG 3.32Å; C271-E273 PolarHBondContact O-N 3.19Å; C271-K274 WeakPolarHBondContact O-CB 3.43Å; C271-K274 WeakPolarHBondContact O-CG 3.3Å; C271-K274 PolarHBondContact O-N 2.84Å; C271-K274 VanDerWaalsContact O-N 3.1Å
272L92.5Very high91.1Very high0 Ų061.6 Ų61.60%033%0.326CS..G310 helixtrans-66.8-18.4177.9-57.5-170.6000113.1V204 M207 L263 F266 S270 K274 F275 T276 I284V204-L272 HydrophobicContact CG1-CD2 4.26Å; V204-L272 HydrophobicContact CG2-CD2 3.82Å; M207-L272 HydrophobicContact SD-CD2 4.34Å; L263-L272 HydrophobicContact CD1-CD1 4.45Å; L263-L272 HydrophobicContact CD2-CD1 3.76Å; F266-L272 HydrophobicContact CB-CD1 3.89Å; F266-L272 HydrophobicContact CB-CG 4.42Å; F266-L272 HydrophobicContact CD1-CD2 4.23Å; S270-L272 PolarHBondContact O-N 3.42Å; S270-L272 VanDerWaalsContact O-N 3.12Å; L272-K274 PolarHBondContact O-N 3.16Å; L272-K274 VanDerWaalsContact O-N 3.14Å; L272-F275 HydrophobicContact CD2-CD2 4.5Å; L272-F275 PolarHBondContact O-N 2.89Å; L272-F275 VanDerWaalsContact O-N 3.16Å; L272-T276 PolarHBondContact O-N 3.07Å; L272-I284 HydrophobicContact CB-CD1 3.8Å; L272-I284 HydrophobicContact CB-CG1 4.45Å; L272-I284 HydrophobicContact CD1-CD1 3.44Å; L272-I284 VanDerWaalsContact CD1-CD1 3.44Å; L272-I284 HydrophobicContact CG-CD1 4.27Å
273E90.9Very high91Very high96 Ų9661.5 Ų61.545%0.44933%0.326SS..G310 helixtrans-61.3-20.1172.7-63.1-176.1174.300112.2S270 C271 F275S270-E273 VanDerWaalsContact O-CB 3.26Å; S270-E273 WeakPolarHBondContact O-CB 3.22Å; S270-E273 WeakPolarHBondContact O-CG 3.23Å; S270-E273 PolarHBondContact O-N 2.97Å; C271-E273 PolarHBondContact O-N 3.19Å; E273-F275 VanDerWaalsContact C-N 3.28Å; E273-F275 PolarHBondContact O-N 3.24Å
274K90.5Very high90.9Very high90 Ų9061.5 Ų61.539%0.39133%0.326SS..G310 helixtrans-81.9-8.7-178.9-55-178.6-171.4-174.50113.5K134 C271 L272K134-K274 HydrophobicContact CB-CD 4.42Å; K134-K274 WeakPolarHBondContact O-CD 3.4Å; K134-K274 VanDerWaalsContact O-CE 3.24Å; K134-K274 WeakPolarHBondContact O-CE 3.24Å; K134-K274 PolarHBondContact O-NZ 2.92Å; C271-K274 WeakPolarHBondContact O-CB 3.43Å; C271-K274 WeakPolarHBondContact O-CG 3.3Å; C271-K274 PolarHBondContact O-N 2.84Å; C271-K274 VanDerWaalsContact O-N 3.1Å; L272-K274 PolarHBondContact O-N 3.16Å; L272-K274 VanDerWaalsContact O-N 3.14Å
275F90.4Very high90.9Very high1 Ų158.8 Ų58.80%0.00432%0.317CS..THydrogen-bonded Turntrans-117-4.9-178.5-53.9-68.5000113.1V130 K134 M207 M208 H211 L272 E273V130-F275 HydrophobicContact CG1-CE1 3.83Å; V130-F275 HydrophobicContact CG1-CZ 4.43Å; K134-F275 HydrophobicContact CB-CE1 4.12Å; K134-F275 HydrophobicContact CB-CZ 3.93Å; K134-F275 HydrophobicContact CD-CD1 4.29Å; K134-F275 HydrophobicContact CD-CE1 3.62Å; K134-F275 HydrophobicContact CD-CZ 4.31Å; K134-F275 HydrophobicContact CG-CE1 4.49Å; M207-F275 HydrophobicContact CB-CB 4.28Å; M208-F275 HydrophobicContact CE-CE1 4.35Å; M208-F275 HydrophobicContact CE-CE2 4.08Å; M208-F275 HydrophobicContact CE-CZ 3.65Å; M208-F275 HydrophobicContact CG-CD1 4.26Å; M208-F275 HydrophobicContact CG-CE1 3.79Å; M208-F275 HydrophobicContact CG-CZ 4.01Å; H211-F275 HydrophobicContact CB-CD1 4.18Å; L272-F275 HydrophobicContact CD2-CD2 4.5Å; L272-F275 PolarHBondContact O-N 2.89Å; L272-F275 VanDerWaalsContact O-N 3.16Å; E273-F275 VanDerWaalsContact C-N 3.28Å; E273-F275 PolarHBondContact O-N 3.24Å
276T91.1Very high91Very high30 Ų3056.7 Ų56.718%0.18430%0.301CS..  trans-91.8149.6179.5-168.90000112.3L272 S278 V283 I284 S285L272-T276 PolarHBondContact O-N 3.07Å; T276-S278 WeakPolarHBondContact OG1-CB 3.39Å; T276-S278 PolarHBondContact OG1-N 3.13Å; T276-S278 VanDerWaalsContact OG1-N 3.11Å; T276-V283 PolarHBondContact OG1-O 3.01Å; T276-I284 WeakPolarHBondContact OG1-CA 3.43Å; T276-S285 PolarHBondContact OG1-N 3.24Å
277N84.7Confident91Very high95 Ų9558.8 Ų58.851%0.50831%0.314SS..  trans-104.62.4168.3-67.3-92.9000112.4S285 P287N277-S285 PolarHBondContact N-O 3.45Å; N277-S285 PolarHBondContact ND2-O 3.48Å; N277-P287 WeakPolarHBondContact ND2-CD 3.5Å
278S85.8Confident90.9Very high36 Ų3655.7 Ų55.725%0.25230%0.303SS..  trans-85.4143.6179.7-175.10000111.7T276 D280 S285T276-S278 WeakPolarHBondContact OG1-CB 3.39Å; T276-S278 PolarHBondContact OG1-N 3.13Å; T276-S278 VanDerWaalsContact OG1-N 3.11Å; S278-D280 PolarHBondContact OG-N 3.05Å; S278-D280 PolarHBondContact OG-O 3.11Å; S278-S285 WeakPolarHBondContact CB-OG 3.5Å; S278-S285 PolarHBondContact N-OG 3.16Å; S278-S285 VanDerWaalsContact N-OG 3.13Å
279T84.9Confident91Very high148 Ų14853.4 Ų53.491%0.90828%0.283SS*.SBendtrans-84.2-19165.653.80000112.6K281T279-K281 PolarHBondContact O-N 3Å
280D88.9Confident91.2Very high75 Ų7552.9 Ų52.940%0.40128%0.28SS..SBendtrans-75.3114.8171.6-178.50.4000109.8S278 N282 V283S278-D280 PolarHBondContact OG-N 3.05Å; S278-D280 PolarHBondContact OG-O 3.11Å; D280-N282 PolarHBondContact O-N 3.38Å; D280-N282 VanDerWaalsContact O-N 3.16Å; D280-N282 WeakPolarHBondContact OD1-CB 3.4Å; D280-N282 PolarHBondContact OD1-N 3.29Å; D280-N282 PolarHBondContact OD1-ND2 3.01Å; D280-N282 VanDerWaalsContact OD1-ND2 3.15Å; D280-V283 PolarHBondContact O-N 2.84Å; D280-V283 VanDerWaalsContact O-N 3.17Å; D280-V283 VanDerWaalsContact O-O 3.1Å
281K85Confident91.4Very high151 Ų15152.5 Ų52.566%0.65727%0.272SS*.THydrogen-bonded Turntrans-61.2-22.2179-66.3-168.5175.9-1670113.1R258 T279 V283R258-K281 WeakPolarHBondContact CD-O 3.48Å; R258-K281 PolarHBondContact NE-O 3.19Å; T279-K281 PolarHBondContact O-N 3Å; K281-V283 VanDerWaalsContact C-N 3.28Å; K281-V283 PolarHBondContact O-N 3.49Å
282N91.1Very high91.6Very high86 Ų8652.9 Ų52.946%0.4628%0.275SS..THydrogen-bonded Turntrans-82.4-5-179.3-60.8-64.6000113.9T257 R258 D280T257-N282 PolarHBondContact OG1-O 2.99Å; R258-N282 PolarHBondContact N-O 3.24Å; D280-N282 PolarHBondContact O-N 3.38Å; D280-N282 VanDerWaalsContact O-N 3.16Å; D280-N282 WeakPolarHBondContact OD1-CB 3.4Å; D280-N282 PolarHBondContact OD1-N 3.29Å; D280-N282 PolarHBondContact OD1-ND2 3.01Å; D280-N282 VanDerWaalsContact OD1-ND2 3.15Å
283V94.5Very high91.6Very high25 Ų2553 Ų5315%0.15228%0.275CS..EExtended strand (participates in β ladder)trans-129137.9-173.5179.20000110.3Q255 I256 T276 D280 K281Q255-V283 HydrophobicContact CB-CG1 3.75Å; Q255-V283 HydrophobicContact CG-CG1 4.42Å; I256-V283 WeakPolarHBondContact O-CA 3.3Å; T276-V283 PolarHBondContact OG1-O 3.01Å; D280-V283 PolarHBondContact O-N 2.84Å; D280-V283 VanDerWaalsContact O-N 3.17Å; D280-V283 VanDerWaalsContact O-O 3.1Å; K281-V283 VanDerWaalsContact C-N 3.28Å; K281-V283 PolarHBondContact O-N 3.49Å
284I95.6Very high91.3Very high0 Ų048.5 Ų48.50%026%0.255CS..EExtended strand (participates in β ladder)trans-108.8122.8170.7-59.2161.3000107.1M207 Y250 Q255 I256 R258 L263 L272 T276M207-I284 HydrophobicContact CE-CB 4.08Å; M207-I284 HydrophobicContact CE-CD1 3.79Å; M207-I284 HydrophobicContact CE-CG2 3.69Å; M207-I284 HydrophobicContact CG-CG2 4.43Å; M207-I284 HydrophobicContact SD-CD1 4.3Å; M207-I284 HydrophobicContact SD-CG2 3.79Å; Y250-I284 HydrophobicContact CE2-CG2 4.07Å; Q255-I284 CarbonylContact C-O 3.5Å; Q255-I284 VanDerWaalsContact CA-O 3.23Å; Q255-I284 WeakPolarHBondContact CA-O 3.48Å; I256-I284 HydrophobicContact CG2-CB 4.17Å; I256-I284 PolarHBondContact N-O 3.1Å; I256-I284 PolarHBondContact O-N 2.78Å; R258-I284 HydrophobicContact CG-CD1 4.03Å; R258-I284 HydrophobicContact CG-CG1 4.06Å; L263-I284 HydrophobicContact CD1-CD1 4.19Å; L272-I284 HydrophobicContact CB-CD1 3.8Å; L272-I284 HydrophobicContact CB-CG1 4.45Å; L272-I284 HydrophobicContact CD1-CD1 3.44Å; L272-I284 VanDerWaalsContact CD1-CD1 3.44Å; L272-I284 HydrophobicContact CG-CD1 4.27Å; T276-I284 WeakPolarHBondContact OG1-CA 3.43Å
285S96.4Very high90.8Very high18 Ų1847 Ų4713%0.12625%0.251CS..EExtended strand (participates in β ladder)trans-134.2158-174.170.30000113.9G254 T276 N277 S278G254-S285 CarbonylContact O-C 3.5Å; G254-S285 WeakPolarHBondContact O-CA 3.31Å; G254-S285 VanDerWaalsContact O-CB 3.3Å; G254-S285 WeakPolarHBondContact O-CB 3.48Å; T276-S285 PolarHBondContact OG1-N 3.24Å; N277-S285 PolarHBondContact N-O 3.45Å; N277-S285 PolarHBondContact ND2-O 3.48Å; S278-S285 WeakPolarHBondContact CB-OG 3.5Å; S278-S285 PolarHBondContact N-OG 3.16Å; S278-S285 VanDerWaalsContact N-OG 3.13Å
286H95.7Very high90.1Very high11 Ų1151.7 Ų51.75%0.05128%0.275CS..  trans-127.7154.4169.664.991.2000111.4T210 Y250 L251 G254 L288T210-H286 HydrophobicContact CG2-CB 4.48Å; Y250-H286 AromaticContact CE1-CD2 3.54Å; Y250-H286 AromaticContact CE2-CD2 3.63Å; Y250-H286 AromaticContact CZ-CD2 3.33Å; Y250-H286 PolarHBondContact O-NE2 3.27Å; L251-H286 WeakPolarHBondContact CA-NE2 3.46Å; L251-H286 PolarHBondContact O-CE1 3.03Å; L251-H286 PolarHBondContact O-NE2 3.1Å; G254-H286 WeakPolarHBondContact CA-NE2 3.5Å; G254-H286 PolarHBondContact O-N 3.14Å; H286-L288 PolarHBondContact CE1-O 3.05Å; H286-L288 WeakPolarHBondContact ND1-CB 3.36Å; H286-L288 PolarHBondContact ND1-N 2.98Å; H286-L288 PolarHBondContact ND1-O 3.17Å
287P94.1Very high89.7Confident43 Ų4357.5 Ų57.528%0.27931%0.305SS..SBendtrans-82.7-15.5-176.333.6-37000113.1N277 R289N277-P287 WeakPolarHBondContact ND2-CD 3.5Å; P287-R289 PolarHBondContact O-N 3.39Å
288L91.3Very high89.6Confident6 Ų655.1 Ų55.13%0.03130%0.295CS..  trans-68.897.6-179-44.8176000108.1T210 V213 L217 I235 H286 L290T210-L288 HydrophobicContact CG2-CD1 4.23Å; V213-L288 HydrophobicContact CB-CD1 3.93Å; V213-L288 HydrophobicContact CG1-CD1 3.63Å; V213-L288 HydrophobicContact CG1-CD2 4.23Å; L217-L288 HydrophobicContact CD1-CD2 3.3Å; L217-L288 HydrophobicContact CG-CD2 4.5Å; I235-L288 HydrophobicContact CD1-CD1 4.02Å; H286-L288 PolarHBondContact CE1-O 3.05Å; H286-L288 WeakPolarHBondContact ND1-CB 3.36Å; H286-L288 PolarHBondContact ND1-N 2.98Å; H286-L288 PolarHBondContact ND1-O 3.17Å; L288-L290 HydrophobicContact CB-CD1 4.21Å; L288-L290 HydrophobicContact CB-CD2 4.03Å; L288-L290 HydrophobicContact CB-CG 3.9Å; L288-L290 WeakPolarHBondContact O-CG 3.26Å; L288-L290 PolarHBondContact O-N 2.84Å
289R91.9Very high89.7Confident110 Ų11053.8 Ų53.842%0.41529%0.286SS..  trans-72.197.4173.8-64.3178.3-178-153-4.3107.4P287 P319 Q371P287-R289 PolarHBondContact O-N 3.39Å; R289-P319 WeakPolarHBondContact O-CD 3.17Å; R289-Q371 VanDerWaalsContact NH1-OE1 3.12Å
290L96.6Very high89.9Confident9 Ų949.8 Ų49.85%0.04726%0.262CS..  trans-102.3142.5-173.8-60.9171.4000110.3I235 L251 L288 F316 A317 T318I235-L290 HydrophobicContact CD1-CD1 3.89Å; I235-L290 HydrophobicContact CD1-CD2 4.39Å; L251-L290 HydrophobicContact CD2-CD1 4.2Å; L251-L290 WeakPolarHBondContact O-CB 3.43Å; L288-L290 HydrophobicContact CB-CD1 4.21Å; L288-L290 HydrophobicContact CB-CD2 4.03Å; L288-L290 HydrophobicContact CB-CG 3.9Å; L288-L290 WeakPolarHBondContact O-CG 3.26Å; L288-L290 PolarHBondContact O-N 2.84Å; L290-F316 HydrophobicContact CB-CB 4.1Å; L290-F316 HydrophobicContact CB-CD1 3.94Å; L290-F316 HydrophobicContact CB-CG 4.37Å; L290-F316 HydrophobicContact CD1-CB 4.2Å; L290-F316 HydrophobicContact CD2-CB 4.31Å; L290-F316 HydrophobicContact CG-CB 4.42Å; L290-A317 CarbonylContact C-O 3.54Å; L290-A317 WeakPolarHBondContact CA-O 3.17Å; L290-T318 HydrophobicContact CD2-CG2 4.17Å
291D95.4Very high90.1Very high70 Ų7047.6 Ų47.637%0.37425%0.249SC..EExtended strand (participates in β ladder)trans-122133.1169.3-175.749.4000108.6F316 A317 P319 R324D291-F316 WeakPolarHBondContact O-CA 3.42Å; D291-A317 PolarHBondContact N-O 2.9Å; D291-A317 PolarHBondContact O-N 3.33Å; D291-P319 HydrophobicContact CB-CB 4.28Å; D291-P319 HydrophobicContact CB-CG 4.03Å; D291-R324 IonicContact OD2-CZ 2.75Å; D291-R324 IonicContact OD2-NH1 2.73Å; D291-R324 PolarHBondContact OD2-NH1 2.89Å; D291-R324 IonicContact OD2-NH2 2.64Å
292S95.9Very high90.6Very high11 Ų1140.4 Ų40.48%0.07722%0.218CC..EExtended strand (participates in β ladder)trans-76.5133.6176.8-179.50000109.8C294 I315 R324S292-C294 VanDerWaalsContact C-N 3.25Å; S292-C294 WeakPolarHBondContact CB-O 3.32Å; S292-C294 PolarHBondContact OG-N 2.73Å; S292-C294 VanDerWaalsContact OG-N 3.17Å; S292-C294 PolarHBondContact OG-O 3.43Å; S292-I315 CarbonylContact C-O 3.6Å; S292-R324 PolarHBondContact O-NH1 2.93Å
293A92.9Very high90.9Very high1 Ų136.8 Ų36.81%0.00820%0.199CC..SBendtrans-65-34.8169.100000111.7I315 I327 A358 Y360A293-I315 HydrophobicContact CB-CB 3.92Å; A293-I315 HydrophobicContact CB-CG2 4.19Å; A293-I315 WeakPolarHBondContact CB-O 3.25Å; A293-I315 PolarHBondContact N-O 3.29Å; A293-I327 HydrophobicContact CB-CG2 4.12Å; A293-I327 WeakPolarHBondContact O-CG2 3.45Å; A293-A358 HydrophobicContact CB-CB 3.84Å; A293-Y360 WeakPolarHBondContact CB-OH 3.38Å
294C84.4Confident91.1Very high3 Ų336.9 Ų36.92%0.0220%0.196CC..  trans-99.8132-174.1-560000109.8S292 I299 M311S292-C294 VanDerWaalsContact C-N 3.25Å; S292-C294 WeakPolarHBondContact CB-O 3.32Å; S292-C294 PolarHBondContact OG-N 2.73Å; S292-C294 VanDerWaalsContact OG-N 3.17Å; S292-C294 PolarHBondContact OG-O 3.43Å; C294-I299 HydrophobicContact CB-CD1 4.11Å; C294-M311 HydrophobicContact CB-CE 4.06Å; C294-M311 HydrophobicContact CB-SD 4.01Å
295D80.6Confident91.1Very high58 Ų5837.8 Ų37.831%0.3120%0.202SC..  trans-125.8151.6170.777.283.6000110N297 S298 I299D295-N297 PolarHBondContact O-N 3.33Å; D295-N297 VanDerWaalsContact O-N 3.17Å; D295-N297 WeakPolarHBondContact OD1-CA 3.42Å; D295-N297 WeakPolarHBondContact OD1-CB 3.23Å; D295-N297 PolarHBondContact OD1-N 3.41Å; D295-N297 PolarHBondContact OD1-ND2 3.42Å; D295-S298 PolarHBondContact O-N 3.09Å; D295-S298 PolarHBondContact OD1-N 3Å; D295-S298 VanDerWaalsContact OD1-N 3.08Å; D295-S298 PolarHBondContact OD1-OG 2.9Å; D295-S298 WeakPolarHBondContact OD2-CB 3.44Å; D295-S298 PolarHBondContact OD2-OG 3.21Å; D295-I299 PolarHBondContact O-N 3.09Å
296I76.3Confident91Very high100 Ų10040.5 Ų40.551%0.51321%0.214SC..THydrogen-bonded Turntrans-62.9-22.7-173.7-163.4165.7000113.6P243P243-I296 HydrophobicContact CG-CD1 4.35Å
297N82.1Confident91Very high151 Ų15146.6 Ų46.681%0.80725%0.247SC*.THydrogen-bonded Turntrans-78.1-29.3177.3-51-59.6000111.2D295D295-N297 PolarHBondContact O-N 3.33Å; D295-N297 VanDerWaalsContact O-N 3.17Å; D295-N297 WeakPolarHBondContact OD1-CA 3.42Å; D295-N297 WeakPolarHBondContact OD1-CB 3.23Å; D295-N297 PolarHBondContact OD1-N 3.41Å; D295-N297 PolarHBondContact OD1-ND2 3.42Å
298S81.9Confident91Very high45 Ų4546.9 Ų46.932%0.31524%0.244SC..THydrogen-bonded Turntrans-88.3-40.9179.8-59.50000112.7D295 P330D295-S298 PolarHBondContact O-N 3.09Å; D295-S298 PolarHBondContact OD1-N 3Å; D295-S298 VanDerWaalsContact OD1-N 3.08Å; D295-S298 PolarHBondContact OD1-OG 2.9Å; D295-S298 WeakPolarHBondContact OD2-CB 3.44Å; D295-S298 PolarHBondContact OD2-OG 3.21Å; S298-P330 WeakPolarHBondContact O-CB 3.5Å; S298-P330 WeakPolarHBondContact O-CD 3.49Å; S298-P330 WeakPolarHBondContact O-CG 3.41Å
299I88.6Confident91.2Very high9 Ų950.9 Ų50.95%0.04626%0.262CS..  trans-128.9104.8-176.8-62.1173000108C294 D295 F301 T302 M311 I327 I356C294-I299 HydrophobicContact CB-CD1 4.11Å; D295-I299 PolarHBondContact O-N 3.09Å; I299-F301 VanDerWaalsContact C-N 3.35Å; I299-F301 WeakPolarHBondContact CG2-O 3.41Å; I299-F301 PolarHBondContact O-N 3.09Å; I299-T302 HydrophobicContact CG2-CG2 3.92Å; I299-M311 HydrophobicContact CB-CE 3.82Å; I299-M311 HydrophobicContact CG2-CE 4.14Å; I299-M311 WeakPolarHBondContact O-CE 3.1Å; I299-I327 HydrophobicContact CD1-CD1 4.31Å; I299-I356 HydrophobicContact CD1-CG2 4.27Å
300P88.4Confident91.4Very high64 Ų6445.9 Ų45.942%0.41624%0.244SC..SBendtrans-73.2-27.6-173.326.9-33.6000113.3
301F93.3Very high91.3Very high29 Ų2945.6 Ų45.613%0.12724%0.243CC..  trans-152.7149.9-179.947.3-99.6000110.9I299 Y304 F331 I354I299-F301 VanDerWaalsContact C-N 3.35Å; I299-F301 WeakPolarHBondContact CG2-O 3.41Å; I299-F301 PolarHBondContact O-N 3.09Å; F301-Y304 AromaticContact CD1-CD2 3.99Å; F301-Y304 HydrophobicContact CD1-CD2 3.99Å; F301-Y304 HydrophobicContact CD1-CE2 4.37Å; F301-Y304 AromaticContact CD2-CD2 3.67Å; F301-Y304 HydrophobicContact CD2-CD2 3.67Å; F301-Y304 HydrophobicContact CD2-CG 4.23Å; F301-Y304 AromaticContact CE1-CD2 3.93Å; F301-Y304 HydrophobicContact CE1-CD2 3.93Å; F301-Y304 AromaticContact CE1-CE2 3.99Å; F301-Y304 HydrophobicContact CE1-CE2 3.99Å; F301-Y304 AromaticContact CE2-CD2 3.6Å; F301-Y304 HydrophobicContact CE2-CD2 3.6Å; F301-Y304 HydrophobicContact CE2-CE2 4.25Å; F301-Y304 HydrophobicContact CE2-CG 4.19Å; F301-Y304 AromaticContact CG-CD2 3.88Å; F301-Y304 HydrophobicContact CG-CD2 3.88Å; F301-Y304 AromaticContact CZ-CD2 3.74Å; F301-Y304 HydrophobicContact CZ-CD2 3.74Å; F301-Y304 AromaticContact CZ-CE2 3.93Å; F301-Y304 HydrophobicContact CZ-CE2 3.93Å; F301-F331 HydrophobicContact CE2-CB 4.48Å; F301-I354 HydrophobicContact CD2-CD1 3.44Å; F301-I354 VanDerWaalsContact CD2-CD1 3.44Å; F301-I354 HydrophobicContact CE2-CD1 3.37Å
302T96.4Very high91.5Very high0 Ų042.5 Ų42.50%023%0.226CC..SBendtrans-121-21.8170.864.10000111.3I299 G310 M311 I312 D313 H353 I354 I356I299-T302 HydrophobicContact CG2-CG2 3.92Å; T302-G310 PolarHBondContact N-O 3.4Å; T302-M311 HydrophobicContact CG2-CB 4.42Å; T302-M311 HydrophobicContact CG2-CG 3.95Å; T302-I312 PolarHBondContact OG1-N 3.23Å; T302-D313 WeakPolarHBondContact CB-OD2 3.36Å; T302-D313 HydrophobicContact CG2-CB 4.21Å; T302-D313 WeakPolarHBondContact OG1-CB 3.41Å; T302-D313 PolarHBondContact OG1-N 3.14Å; T302-D313 PolarHBondContact OG1-OD2 3Å; T302-H353 CarbonylContact O-C 3.57Å; T302-H353 WeakPolarHBondContact O-CA 2.96Å; T302-I354 PolarHBondContact O-N 3.18Å; T302-I356 HydrophobicContact CG2-CG2 3.66Å
303N97.8Very high91.6Very high10 Ų1042.1 Ų42.15%0.05322%0.223CC..EExtended strand (participates in β ladder)trans-112.4134.7162.2-179.4-78.8000109.4F308 K309 G310 I312 D352 H353N303-F308 HydrophobicContact CB-CD1 4.33Å; N303-F308 HydrophobicContact CB-CE1 4.2Å; N303-F308 WeakPolarHBondContact OD1-CD1 3.21Å; N303-K309 WeakPolarHBondContact O-CA 3.39Å; N303-G310 PolarHBondContact N-O 2.8Å; N303-G310 PolarHBondContact O-N 3.01Å; N303-G310 VanDerWaalsContact O-N 3.08Å; N303-I312 HydrophobicContact CB-CD1 3.67Å; N303-I312 HydrophobicContact CB-CG1 3.84Å; N303-D352 WeakPolarHBondContact CA-O 3.34Å; N303-D352 PolarHBondContact ND2-OD2 2.74Å; N303-H353 PolarHBondContact ND2-CD2 2.62Å; N303-H353 PolarHBondContact ND2-NE2 3.29Å
304Y97.1Very high91.8Very high26 Ų2642.2 Ų42.210%0.10222%0.223CC..EExtended strand (participates in β ladder)trans-138.192.9-177-170.5-87.1000110.1F301 K309 V336 I341 G343 F344 D352F301-Y304 AromaticContact CD1-CD2 3.99Å; F301-Y304 HydrophobicContact CD1-CD2 3.99Å; F301-Y304 HydrophobicContact CD1-CE2 4.37Å; F301-Y304 AromaticContact CD2-CD2 3.67Å; F301-Y304 HydrophobicContact CD2-CD2 3.67Å; F301-Y304 HydrophobicContact CD2-CG 4.23Å; F301-Y304 AromaticContact CE1-CD2 3.93Å; F301-Y304 HydrophobicContact CE1-CD2 3.93Å; F301-Y304 AromaticContact CE1-CE2 3.99Å; F301-Y304 HydrophobicContact CE1-CE2 3.99Å; F301-Y304 AromaticContact CE2-CD2 3.6Å; F301-Y304 HydrophobicContact CE2-CD2 3.6Å; F301-Y304 HydrophobicContact CE2-CE2 4.25Å; F301-Y304 HydrophobicContact CE2-CG 4.19Å; F301-Y304 AromaticContact CG-CD2 3.88Å; F301-Y304 HydrophobicContact CG-CD2 3.88Å; F301-Y304 AromaticContact CZ-CD2 3.74Å; F301-Y304 HydrophobicContact CZ-CD2 3.74Å; F301-Y304 AromaticContact CZ-CE2 3.93Å; F301-Y304 HydrophobicContact CZ-CE2 3.93Å; Y304-K309 HydrophobicContact CD2-CB 4.29Å; Y304-K309 HydrophobicContact CD2-CD 3.84Å; Y304-K309 HydrophobicContact CD2-CG 3.72Å; Y304-K309 HydrophobicContact CE2-CD 3.47Å; Y304-K309 VanDerWaalsContact CE2-CD 3.47Å; Y304-K309 HydrophobicContact CE2-CG 3.92Å; Y304-K309 HydrophobicContact CG-CG 4.24Å; Y304-K309 WeakPolarHBondContact OH-CE 3.38Å; Y304-V336 HydrophobicContact CE1-CG1 4.2Å; Y304-V336 WeakPolarHBondContact OH-CG1 3.28Å; Y304-I341 HydrophobicContact CE1-CG2 4.49Å; Y304-I341 PolarHBondContact OH-O 2.75Å; Y304-G343 CarbonylContact O-C 3.54Å; Y304-F344 AromaticContact CD1-CD2 3.98Å; Y304-F344 HydrophobicContact CD1-CD2 3.98Å; Y304-F344 HydrophobicContact CD1-CE2 4.12Å; Y304-F344 HydrophobicContact CD1-CG 4.18Å; Y304-F344 HydrophobicContact CD1-CZ 4.47Å; Y304-F344 HydrophobicContact CG-CD2 4.17Å; Y304-F344 HydrophobicContact CG-CE2 4.25Å; Y304-F344 WeakPolarHBondContact O-CA 3.3Å; Y304-F344 WeakPolarHBondContact O-CB 3.48Å; Y304-F344 PolarHBondContact O-N 3.16Å; Y304-D352 PolarHBondContact N-O 3.45Å
305T96.9Very high92.5Very high19 Ų1942 Ų4212%0.11722%0.222CC..  trans-114.3177.3174.363.90000110.7Y32 Y34 D307 F308 K309 D352Y32-T305 HydrophobicContact CE1-CG2 4.02Å; Y34-T305 WeakPolarHBondContact OH-CA 3.37Å; Y34-T305 WeakPolarHBondContact OH-CB 3.49Å; T305-D307 VanDerWaalsContact C-N 3.35Å; T305-F308 PolarHBondContact N-O 3.04Å; T305-F308 PolarHBondContact OG1-N 2.93Å; T305-F308 PolarHBondContact OG1-O 2.98Å; T305-K309 PolarHBondContact O-NZ 2.67Å; T305-D352 HydrophobicContact CG2-CB 3.79Å
306L94.4Very high93.4Very high75 Ų7539.3 Ų39.339%0.39321%0.208SC..SBendtrans-57.6-49.1173.8-178.367.3000111.4Y34 K309 L342Y34-L306 HydrophobicContact CD1-CB 3.73Å; Y34-L306 HydrophobicContact CD1-CD2 4.15Å; Y34-L306 HydrophobicContact CD1-CG 4.47Å; Y34-L306 HydrophobicContact CE1-CB 3.41Å; Y34-L306 VanDerWaalsContact CE1-CB 3.41Å; Y34-L306 PolarHBondContact OH-N 3.08Å; L306-K309 PolarHBondContact O-NZ 2.8Å; L306-L342 HydrophobicContact CD1-CB 4.08Å
307D93.9Very high94.4Very high139 Ų13934.6 Ų34.674%0.74318%0.184SC*.SBendtrans-90-25.2-170.1-59.8-38.5000113.5T305T305-D307 VanDerWaalsContact C-N 3.35Å
308F95.8Very high95.1Very high49 Ų4927.6 Ų27.622%0.21515%0.146CC..  trans-136134-177.7178.6-100.6000112.1L242 N303 T305 I312 L398L242-F308 HydrophobicContact CD2-CE2 4.28Å; L242-F308 HydrophobicContact CD2-CZ 3.89Å; L242-F308 HydrophobicContact CG-CZ 4.47Å; N303-F308 HydrophobicContact CB-CD1 4.33Å; N303-F308 HydrophobicContact CB-CE1 4.2Å; N303-F308 WeakPolarHBondContact OD1-CD1 3.21Å; T305-F308 PolarHBondContact N-O 3.04Å; T305-F308 PolarHBondContact OG1-N 2.93Å; T305-F308 PolarHBondContact OG1-O 2.98Å; F308-I312 HydrophobicContact CE1-CD1 4.08Å; F308-I312 HydrophobicContact CE1-CG1 4.49Å; F308-I312 HydrophobicContact CE1-CG2 3.96Å; F308-I312 HydrophobicContact CZ-CG2 3.78Å; F308-L398 HydrophobicContact CD2-CD1 4.15Å; F308-L398 HydrophobicContact CD2-CD2 4.46Å
309K95.3Very high95.8Very high91 Ų9128.4 Ų28.440%0.39615%0.151SC..EExtended strand (participates in β ladder)trans-138.4116.3174.8-62.9171.2175.164.20107.6N303 Y304 T305 L306 L342N303-K309 WeakPolarHBondContact O-CA 3.39Å; Y304-K309 HydrophobicContact CD2-CB 4.29Å; Y304-K309 HydrophobicContact CD2-CD 3.84Å; Y304-K309 HydrophobicContact CD2-CG 3.72Å; Y304-K309 HydrophobicContact CE2-CD 3.47Å; Y304-K309 VanDerWaalsContact CE2-CD 3.47Å; Y304-K309 HydrophobicContact CE2-CG 3.92Å; Y304-K309 HydrophobicContact CG-CG 4.24Å; Y304-K309 WeakPolarHBondContact OH-CE 3.38Å; T305-K309 PolarHBondContact O-NZ 2.67Å; L306-K309 PolarHBondContact O-NZ 2.8Å; K309-L342 PolarHBondContact NZ-O 3.37Å
310G95Very high96Very high5 Ų529.6 Ų29.65%0.05216%0.156CC..EExtended strand (participates in β ladder)trans-172.7163-175.800000113.8T302 N303T302-G310 PolarHBondContact N-O 3.4Å; N303-G310 PolarHBondContact N-O 2.8Å; N303-G310 PolarHBondContact O-N 3.01Å; N303-G310 VanDerWaalsContact O-N 3.08Å
311M96.1Very high96.3Very high2 Ų226.6 Ų26.61%0.0114%0.136CC..  trans-84.8112.4171178.8-176.9-59.500108.6P243 C294 I299 T302 Y314P243-M311 HydrophobicContact CG-CB 4.07Å; P243-M311 HydrophobicContact CG-CG 4.33Å; P243-M311 HydrophobicContact CG-SD 4.02Å; C294-M311 HydrophobicContact CB-CE 4.06Å; C294-M311 HydrophobicContact CB-SD 4.01Å; I299-M311 HydrophobicContact CB-CE 3.82Å; I299-M311 HydrophobicContact CG2-CE 4.14Å; I299-M311 WeakPolarHBondContact O-CE 3.1Å; T302-M311 HydrophobicContact CG2-CB 4.42Å; T302-M311 HydrophobicContact CG2-CG 3.95Å; M311-Y314 HydrophobicContact CG-CD1 4.36Å; M311-Y314 HydrophobicContact CG-CE1 3.67Å; M311-Y314 PolarHBondContact O-OH 2.64Å; M311-Y314 HydrophobicContact SD-CD1 4.05Å; M311-Y314 HydrophobicContact SD-CE1 3.46Å; M311-Y314 WeakPolarHBondContact SD-CE1 3.43Å
312I97.8Very high96.5Very high6 Ų625.3 Ų25.33%0.03113%0.131CC..  trans-128.7-6.1176.357.7171.7000112.9F239 L242 T302 N303 F308 Y314F239-I312 PolarHBondContact N-O 2.99Å; L242-I312 HydrophobicContact CD2-CG2 4.3Å; T302-I312 PolarHBondContact OG1-N 3.23Å; N303-I312 HydrophobicContact CB-CD1 3.67Å; N303-I312 HydrophobicContact CB-CG1 3.84Å; F308-I312 HydrophobicContact CE1-CD1 4.08Å; F308-I312 HydrophobicContact CE1-CG1 4.49Å; F308-I312 HydrophobicContact CE1-CG2 3.96Å; F308-I312 HydrophobicContact CZ-CG2 3.78Å; I312-Y314 WeakPolarHBondContact O-CE2 3.44Å
313D98.4Very high96.5Very high3 Ų326.2 Ų26.22%0.01614%0.138CC..EExtended strand (participates in β ladder)trans-104.9137.4176.3-52-85.8000110.1G237 D238 T302 H353 I356G237-D313 VanDerWaalsContact O-CA 3.31Å; G237-D313 WeakPolarHBondContact O-CA 3.41Å; D238-D313 WeakPolarHBondContact CB-OD1 3.43Å; T302-D313 WeakPolarHBondContact CB-OD2 3.36Å; T302-D313 HydrophobicContact CG2-CB 4.21Å; T302-D313 WeakPolarHBondContact OG1-CB 3.41Å; T302-D313 PolarHBondContact OG1-N 3.14Å; T302-D313 PolarHBondContact OG1-OD2 3Å; D313-H353 IonicContact OD1-CE1 3.62Å; D313-H353 IonicContact OD1-ND1 3.52Å; D313-H353 PolarHBondContact OD1-ND1 3.35Å; D313-H353 IonicContact OD2-CE1 3.9Å; D313-H353 IonicContact OD2-CG 3.26Å; D313-H353 IonicContact OD2-ND1 3.18Å; D313-H353 PolarHBondContact OD2-ND1 2.83Å; D313-I356 HydrophobicContact CB-CD1 4Å; D313-I356 WeakPolarHBondContact O-CD1 3.05Å
314Y98.2Very high96.4Very high2 Ų230.6 Ų30.61%0.00815%0.154CC..EExtended strand (participates in β ladder)trans-139.4151.4-175.6-56.7-84.2000112.7C236 G237 F239 S241 L242 P243 F248 M311 I312 F316C236-Y314 CarbonylContact C-O 3.28Å; C236-Y314 VanDerWaalsContact CA-O 3.25Å; C236-Y314 WeakPolarHBondContact CA-O 3.33Å; G237-Y314 PolarHBondContact N-O 3.03Å; G237-Y314 PolarHBondContact O-N 3.2Å; F239-Y314 HydrophobicContact CB-CD2 3.96Å; F239-Y314 HydrophobicContact CB-CE2 4.12Å; F239-Y314 AromaticContact CD2-CD2 3.71Å; F239-Y314 HydrophobicContact CD2-CD2 3.71Å; F239-Y314 HydrophobicContact CD2-CG 4.45Å; F239-Y314 HydrophobicContact CG-CD2 4.07Å; S241-Y314 WeakPolarHBondContact O-CE2 3.39Å; S241-Y314 PolarHBondContact O-OH 3Å; L242-Y314 VanDerWaalsContact C-OH 3.24Å; P243-Y314 WeakPolarHBondContact CD-OH 3.33Å; P243-Y314 HydrophobicContact CG-CE1 4.49Å; F248-Y314 AromaticContact CD2-CD1 3.86Å; F248-Y314 HydrophobicContact CD2-CD1 3.86Å; F248-Y314 AromaticContact CD2-CE1 3.36Å; F248-Y314 HydrophobicContact CD2-CE1 3.36Å; F248-Y314 HydrophobicContact CD2-CE2 4.46Å; F248-Y314 AromaticContact CD2-CZ 3.72Å; F248-Y314 AromaticContact CE2-CD1 3.67Å; F248-Y314 HydrophobicContact CE2-CD1 3.67Å; F248-Y314 AromaticContact CE2-CE1 3.4Å; F248-Y314 HydrophobicContact CE2-CE1 3.4Å; F248-Y314 VanDerWaalsContact CE2-CE1 3.4Å; M311-Y314 HydrophobicContact CG-CD1 4.36Å; M311-Y314 HydrophobicContact CG-CE1 3.67Å; M311-Y314 PolarHBondContact O-OH 2.64Å; M311-Y314 HydrophobicContact SD-CD1 4.05Å; M311-Y314 HydrophobicContact SD-CE1 3.46Å; M311-Y314 WeakPolarHBondContact SD-CE1 3.43Å; I312-Y314 WeakPolarHBondContact O-CE2 3.44Å; Y314-F316 VanDerWaalsContact CB-CE2 3.41Å; Y314-F316 HydrophobicContact CD1-CE2 4.34Å; Y314-F316 HydrophobicContact CD1-CZ 4.36Å; Y314-F316 HydrophobicContact CD2-CE2 4.3Å; Y314-F316 AromaticContact CG-CE2 3.77Å; Y314-F316 HydrophobicContact CG-CE2 3.77Å; Y314-F316 HydrophobicContact CG-CZ 4.24Å
315I98.5Very high96.2Very high0 Ų033.1 Ų33.10%017%0.169CC..EExtended strand (participates in β ladder)trans-118.1104.3164.3-63.5162.5000106.5V16 C18 L234 S292 A293 I356 A358 Y360V16-I315 HydrophobicContact CG1-CD1 4.28Å; V16-I315 HydrophobicContact CG1-CG2 3.86Å; C18-I315 HydrophobicContact CB-CD1 4.18Å; C18-I315 HydrophobicContact CB-CG1 3.82Å; L234-I315 HydrophobicContact CD2-CG2 4.21Å; S292-I315 CarbonylContact C-O 3.6Å; A293-I315 HydrophobicContact CB-CB 3.92Å; A293-I315 HydrophobicContact CB-CG2 4.19Å; A293-I315 WeakPolarHBondContact CB-O 3.25Å; A293-I315 PolarHBondContact N-O 3.29Å; I315-I356 HydrophobicContact CD1-CB 4.38Å; I315-I356 HydrophobicContact CD1-CD1 4.1Å; I315-I356 HydrophobicContact CD1-CG1 3.85Å; I315-I356 HydrophobicContact CG1-CD1 3.85Å; I315-I356 HydrophobicContact CG1-CG1 4.08Å; I315-A358 HydrophobicContact CD1-CB 4.3Å; I315-Y360 HydrophobicContact CG2-CE2 4.19Å
316F98.6Very high96.1Very high0 Ų033.7 Ų33.70%018%0.179CC..EExtended strand (participates in β ladder)trans-94.5136172.7-73.7-79.6000110.3L234 I235 F239 F248 L251 L290 D291 Y314L234-F316 CarbonylContact C-O 3.51Å; L234-F316 WeakPolarHBondContact CA-O 3.43Å; I235-F316 HydrophobicContact CB-CB 4.29Å; I235-F316 PolarHBondContact N-O 3.44Å; I235-F316 PolarHBondContact O-N 3.45Å; F239-F316 HydrophobicContact CE2-CD2 4.43Å; F239-F316 HydrophobicContact CE2-CE2 4.47Å; F239-F316 HydrophobicContact CZ-CD2 4.43Å; F248-F316 AromaticContact CD2-CZ 3.8Å; F248-F316 HydrophobicContact CD2-CZ 3.8Å; F248-F316 HydrophobicContact CE2-CE1 4.2Å; F248-F316 AromaticContact CE2-CZ 3.81Å; F248-F316 HydrophobicContact CE2-CZ 3.81Å; L251-F316 HydrophobicContact CB-CE1 4.03Å; L251-F316 HydrophobicContact CB-CE2 4.19Å; L251-F316 HydrophobicContact CB-CZ 3.86Å; L251-F316 HydrophobicContact CD1-CD2 4.21Å; L251-F316 HydrophobicContact CD1-CE2 3.65Å; L251-F316 HydrophobicContact CD1-CZ 4.07Å; L290-F316 HydrophobicContact CB-CB 4.1Å; L290-F316 HydrophobicContact CB-CD1 3.94Å; L290-F316 HydrophobicContact CB-CG 4.37Å; L290-F316 HydrophobicContact CD1-CB 4.2Å; L290-F316 HydrophobicContact CD2-CB 4.31Å; L290-F316 HydrophobicContact CG-CB 4.42Å; D291-F316 WeakPolarHBondContact O-CA 3.42Å; Y314-F316 VanDerWaalsContact CB-CE2 3.41Å; Y314-F316 HydrophobicContact CD1-CE2 4.34Å; Y314-F316 HydrophobicContact CD1-CZ 4.36Å; Y314-F316 HydrophobicContact CD2-CE2 4.3Å; Y314-F316 AromaticContact CG-CE2 3.77Å; Y314-F316 HydrophobicContact CG-CE2 3.77Å; Y314-F316 HydrophobicContact CG-CZ 4.24Å
317A98.2Very high96.1Very high2 Ų232.7 Ų32.72%0.01717%0.173CC..EExtended strand (participates in β ladder)trans-132.6157.8178.200000111.3V233 L234 L290 D291 P319 L322 Y360V233-A317 WeakPolarHBondContact O-CA 3.45Å; L234-A317 HydrophobicContact CD2-CB 3.7Å; L290-A317 CarbonylContact C-O 3.54Å; L290-A317 WeakPolarHBondContact CA-O 3.17Å; D291-A317 PolarHBondContact N-O 2.9Å; D291-A317 PolarHBondContact O-N 3.33Å; A317-P319 WeakPolarHBondContact O-CD 3.48Å; A317-L322 HydrophobicContact CB-CB 4.37Å; A317-L322 HydrophobicContact CB-CD1 4.09Å; A317-Y360 HydrophobicContact CB-CD1 4.36Å; A317-Y360 HydrophobicContact CB-CE1 3.51Å; A317-Y360 HydrophobicContact CB-CE2 4.48Å; A317-Y360 WeakPolarHBondContact CB-OH 3.45Å
318T97.5Very high96.2Very high3 Ų329 Ų292%0.01815%0.153CC..  trans-84.1101.9171.143.40000111.3V233 L290 Q320 S321 L322V233-T318 HydrophobicContact CB-CG2 3.83Å; V233-T318 HydrophobicContact CG2-CG2 4.21Å; V233-T318 PolarHBondContact N-OG1 2.97Å; V233-T318 PolarHBondContact O-N 3.34Å; V233-T318 VanDerWaalsContact O-N 3.15Å; V233-T318 PolarHBondContact O-OG1 2.77Å; L290-T318 HydrophobicContact CD2-CG2 4.17Å; T318-Q320 PolarHBondContact O-N 2.77Å; T318-Q320 VanDerWaalsContact O-N 3.08Å; T318-S321 WeakPolarHBondContact CB-OG 3.37Å; T318-S321 PolarHBondContact O-N 2.99Å; T318-S321 PolarHBondContact O-OG 3.11Å; T318-S321 PolarHBondContact OG1-OG 3.31Å; T318-L322 PolarHBondContact O-N 3.05Å
319P95.2Very high95.9Very high63 Ų6329 Ų2941%0.40917%0.166SC..THydrogen-bonded Turntrans-66.9-16.5-172.430-37000113.8R289 D291 A317 S321 L322R289-P319 WeakPolarHBondContact O-CD 3.17Å; D291-P319 HydrophobicContact CB-CB 4.28Å; D291-P319 HydrophobicContact CB-CG 4.03Å; A317-P319 WeakPolarHBondContact O-CD 3.48Å; P319-S321 VanDerWaalsContact C-N 3.29Å; P319-L322 WeakPolarHBondContact CA-O 3.44Å
320Q93.8Very high95.5Very high34 Ų3427.7 Ų27.716%0.15917%0.168CC..THydrogen-bonded Turntrans-70.1-23.5172.962.5-84.813.900113.6T318 Q368T318-Q320 PolarHBondContact O-N 2.77Å; T318-Q320 VanDerWaalsContact O-N 3.08Å; Q320-Q368 WeakPolarHBondContact O-CG 3.25Å
321S95.1Very high95.2Very high0 Ų030.1 Ų30.10%018%0.177CC..THydrogen-bonded Turntrans-124.8-16.2-176.248.50000113.6P232 T318 P319 I363P232-S321 WeakPolarHBondContact CA-OG 3.05Å; T318-S321 WeakPolarHBondContact CB-OG 3.37Å; T318-S321 PolarHBondContact O-N 2.99Å; T318-S321 PolarHBondContact O-OG 3.11Å; T318-S321 PolarHBondContact OG1-OG 3.31Å; P319-S321 VanDerWaalsContact C-N 3.29Å; S321-I363 PolarHBondContact O-N 2.66Å
322L96.6Very high95Very high2 Ų233.8 Ų33.81%0.0120%0.196CC..EExtended strand (participates in β ladder)trans-128.2111176.3-65.1177.1000110.2F14 L185 P232 L234 A317 T318 P319 Y360 A361 I362F14-L322 HydrophobicContact CE1-CD2 3.77Å; F14-L322 HydrophobicContact CZ-CD1 4.49Å; F14-L322 HydrophobicContact CZ-CD2 4.06Å; L185-L322 HydrophobicContact CD1-CD1 4.48Å; P232-L322 HydrophobicContact CB-CD1 4.19Å; P232-L322 HydrophobicContact CB-CD2 3.83Å; P232-L322 HydrophobicContact CB-CG 3.88Å; L234-L322 HydrophobicContact CD2-CD1 3.83Å; L234-L322 HydrophobicContact CG-CD1 3.84Å; A317-L322 HydrophobicContact CB-CB 4.37Å; A317-L322 HydrophobicContact CB-CD1 4.09Å; T318-L322 PolarHBondContact O-N 3.05Å; P319-L322 WeakPolarHBondContact CA-O 3.44Å; L322-Y360 HydrophobicContact CB-CD1 3.8Å; L322-Y360 HydrophobicContact CB-CE1 4.41Å; L322-Y360 HydrophobicContact CB-CG 4.33Å; L322-A361 WeakPolarHBondContact CA-O 3.4Å; L322-I362 HydrophobicContact CD2-CG1 4.11Å
323A95.8Very high94.5Very high19 Ų1937.2 Ų37.216%0.15722%0.219CC..EExtended strand (participates in β ladder)trans-86.9116.2173.600000110I2 L325 Y360 A361 I363I2-A323 HydrophobicContact CD1-CB 4.25Å; A323-L325 PolarHBondContact O-N 2.99Å; A323-Y360 CarbonylContact O-C 3.57Å; A323-Y360 WeakPolarHBondContact O-CA 3.35Å; A323-A361 HydrophobicContact CB-CB 4.32Å; A323-A361 PolarHBondContact N-O 3.08Å; A323-A361 PolarHBondContact O-N 3.28Å; A323-I363 HydrophobicContact CB-CD1 4.14Å; A323-I363 HydrophobicContact CB-CG1 4.19Å
324R95.4Very high94.2Very high102 Ų10243.5 Ų43.539%0.38525%0.248SC..EExtended strand (participates in β ladder)trans-65.8123.3174.5-171.6169.570.4-125.10.8110D291 S292 Y360D291-R324 IonicContact OD2-CZ 2.75Å; D291-R324 IonicContact OD2-NH1 2.73Å; D291-R324 PolarHBondContact OD2-NH1 2.89Å; D291-R324 IonicContact OD2-NH2 2.64Å; S292-R324 PolarHBondContact O-NH1 2.93Å; R324-Y360 HydrophobicContact CB-CD1 4.07Å; R324-Y360 HydrophobicContact CB-CE1 3.75Å; R324-Y360 HydrophobicContact CG-CE1 4.14Å
325L94.7Very high94.1Very high79 Ų7947.2 Ų47.241%0.41426%0.262SS..EExtended strand (participates in β ladder)trans-96.7-33.4178-59.3-174.2000112.2T13 A323 Q359 A361T13-L325 HydrophobicContact CG2-CD1 3.66Å; A323-L325 PolarHBondContact O-N 2.99Å; L325-Q359 HydrophobicContact CB-CB 4.34Å; L325-Q359 HydrophobicContact CB-CG 4.32Å; L325-Q359 HydrophobicContact CD1-CG 4.22Å; L325-Q359 PolarHBondContact N-O 3.11Å; L325-A361 HydrophobicContact CD1-CB 4.04Å; L325-A361 HydrophobicContact CD2-CB 3.94Å; L325-A361 HydrophobicContact CG-CB 4.09Å
326G94Very high93.8Very high31 Ų3147.6 Ų47.632%0.3226%0.264SS..EExtended strand (participates in β ladder)trans-173.9168.9-179.600000112.2A358 Q359G326-A358 WeakPolarHBondContact O-CA 3.07Å; G326-Q359 PolarHBondContact O-N 3.47Å
327I95.4Very high93.5Very high55 Ų5555.1 Ų55.128%0.28230%0.3SS..EExtended strand (participates in β ladder)trans-129.8153.7173.361.1174.7000109.3A293 I299 G329 M357 A358A293-I327 HydrophobicContact CB-CG2 4.12Å; A293-I327 WeakPolarHBondContact O-CG2 3.45Å; I299-I327 HydrophobicContact CD1-CD1 4.31Å; I327-G329 PolarHBondContact O-N 3.48Å; I327-M357 CarbonylContact C-O 3.4Å; I327-M357 WeakPolarHBondContact CA-O 3.45Å; I327-A358 HydrophobicContact CG2-CB 4.1Å
328L93.9Very high93.4Very high62 Ų6259.5 Ų59.533%0.32533%0.33SS..PPolyproline II helixtrans-65.2130.2165.5179.667.6000108.5Y56 M357Y56-L328 HydrophobicContact CD1-CD2 4.08Å; Y56-L328 HydrophobicContact CE1-CD1 4.16Å; Y56-L328 HydrophobicContact CE1-CD2 3.33Å; Y56-L328 HydrophobicContact CE1-CG 4.4Å; L328-M357 HydrophobicContact CB-CB 3.85Å; L328-M357 HydrophobicContact CD2-CB 4.24Å; L328-M357 PolarHBondContact N-O 2.97Å
329G89.8Confident93.4Very high47 Ų4763.3 Ų63.349%0.48535%0.35SS..PPolyproline II helixtrans-62.8165.8-179.800000112.7I327I327-G329 PolarHBondContact O-N 3.48Å
330P88.3Confident93.4Very high65 Ų6568.7 Ų68.742%0.42237%0.367SS..PPolyproline II helixtrans-62.4156.8178.929.1-35.3000110.9S298 D332S298-P330 WeakPolarHBondContact O-CB 3.5Å; S298-P330 WeakPolarHBondContact O-CD 3.49Å; S298-P330 WeakPolarHBondContact O-CG 3.41Å; P330-D332 PolarHBondContact O-N 3.47Å
331F87.6Confident93.4Very high55 Ų5567.5 Ų67.524%0.24136%0.362CS..PPolyproline II helixtrans-58.9135.2167.9-160.4-85.7000109.9F301 P333 W335 V336 F344 V349 I354F301-F331 HydrophobicContact CE2-CB 4.48Å; F331-P333 WeakPolarHBondContact O-CD 3.49Å; F331-W335 AromaticContact CE1-CE3 3.52Å; F331-W335 HydrophobicContact CE1-CE3 3.52Å; F331-W335 AromaticContact CE1-CZ3 3.61Å; F331-W335 HydrophobicContact CE1-CZ3 3.61Å; F331-W335 AromaticContact CZ-CE3 3.98Å; F331-W335 HydrophobicContact CZ-CE3 3.98Å; F331-W335 AromaticContact CZ-CZ3 3.7Å; F331-W335 HydrophobicContact CZ-CZ3 3.7Å; F331-V336 HydrophobicContact CD1-CG2 3.63Å; F331-V336 HydrophobicContact CE1-CG2 3.66Å; F331-F344 HydrophobicContact CD1-CE2 4.49Å; F331-F344 HydrophobicContact CD1-CZ 4.12Å; F331-F344 HydrophobicContact CE1-CE2 4.38Å; F331-F344 AromaticContact CE1-CZ 3.66Å; F331-F344 HydrophobicContact CE1-CZ 3.66Å; F331-F344 HydrophobicContact CE2-CZ 4.46Å; F331-F344 HydrophobicContact CZ-CE2 4.5Å; F331-F344 AromaticContact CZ-CZ 3.86Å; F331-F344 HydrophobicContact CZ-CZ 3.86Å; F331-V349 HydrophobicContact CE2-CG2 4.23Å; F331-V349 HydrophobicContact CZ-CG2 3.81Å; F331-I354 HydrophobicContact CB-CD1 3.73Å; F331-I354 HydrophobicContact CB-CG2 4.18Å; F331-I354 HydrophobicContact CD2-CD1 4.33Å; F331-I354 HydrophobicContact CD2-CG2 4.08Å; F331-I354 HydrophobicContact CG-CD1 4.09Å
332D91.3Very high93.4Very high80 Ų8072.5 Ų72.543%0.42839%0.388SS..  trans-61.8108.9-171.6178.28000111.4P330 Q334 W335 V336P330-D332 PolarHBondContact O-N 3.47Å; D332-Q334 PolarHBondContact O-N 2.87Å; D332-Q334 WeakPolarHBondContact OD1-CB 3.35Å; D332-Q334 PolarHBondContact OD1-N 2.86Å; D332-W335 HydrophobicContact CB-CB 4.02Å; D332-W335 PolarHBondContact O-N 3.21Å; D332-W335 PolarHBondContact OD1-N 3.46Å; D332-W335 PolarHBondContact OD2-N 3.17Å; D332-V336 PolarHBondContact O-N 3.44Å
333P88.8Confident93.4Very high77 Ų7772.5 Ų72.550%0.539%0.388SS..Hα-helixtrans-68.4-26.2-178.429.4-34.5000112F331 V336 Q337F331-P333 WeakPolarHBondContact O-CD 3.49Å; P333-V336 PolarHBondContact O-N 3.25Å; P333-Q337 WeakPolarHBondContact O-CB 3.42Å; P333-Q337 PolarHBondContact O-N 3.03Å
334Q92.6Very high93.5Very high136 Ų13671.6 Ų71.664%0.63638%0.381SS*.Hα-helixtrans-69.8-39.2177.8-61-175.3-200110.8D332 Q337 S338D332-Q334 PolarHBondContact O-N 2.87Å; D332-Q334 WeakPolarHBondContact OD1-CB 3.35Å; D332-Q334 PolarHBondContact OD1-N 2.86Å; Q334-Q337 PolarHBondContact O-N 3.19Å; Q334-S338 VanDerWaalsContact O-CB 3.23Å; Q334-S338 WeakPolarHBondContact O-CB 3.47Å; Q334-S338 PolarHBondContact O-N 3.44Å; Q334-S338 PolarHBondContact O-OG 3.33Å
335W94.4Very high93.6Very high79 Ų7966.8 Ų66.830%0.29936%0.363SS..Hα-helixtrans-63.8-43.7174.1-176.191.3000111.5F331 D332 Q337 S338 N339 I341 H348 V349F331-W335 AromaticContact CE1-CE3 3.52Å; F331-W335 HydrophobicContact CE1-CE3 3.52Å; F331-W335 AromaticContact CE1-CZ3 3.61Å; F331-W335 HydrophobicContact CE1-CZ3 3.61Å; F331-W335 AromaticContact CZ-CE3 3.98Å; F331-W335 HydrophobicContact CZ-CE3 3.98Å; F331-W335 AromaticContact CZ-CZ3 3.7Å; F331-W335 HydrophobicContact CZ-CZ3 3.7Å; D332-W335 HydrophobicContact CB-CB 4.02Å; D332-W335 PolarHBondContact O-N 3.21Å; D332-W335 PolarHBondContact OD1-N 3.46Å; D332-W335 PolarHBondContact OD2-N 3.17Å; W335-Q337 PolarHBondContact O-N 2.93Å; W335-S338 PolarHBondContact O-N 2.92Å; W335-N339 VanDerWaalsContact CD1-ND2 3.33Å; W335-N339 PolarHBondContact NE1-ND2 3.04Å; W335-N339 WeakPolarHBondContact O-CB 3.3Å; W335-N339 PolarHBondContact O-N 3.34Å; W335-N339 PolarHBondContact O-ND2 3.01Å; W335-I341 HydrophobicContact CE3-CD1 3.72Å; W335-I341 HydrophobicContact CH2-CD1 3.41Å; W335-I341 VanDerWaalsContact CH2-CD1 3.41Å; W335-I341 HydrophobicContact CZ2-CD1 4.33Å; W335-I341 HydrophobicContact CZ3-CD1 3.05Å; W335-H348 HydrophobicContact CH2-CB 4.11Å; W335-H348 HydrophobicContact CZ2-CB 4.33Å; W335-V349 HydrophobicContact CH2-CG2 4.38Å; W335-V349 HydrophobicContact CZ3-CG2 4.39Å
336V93.1Very high93.7Very high8 Ų865.1 Ų65.15%0.04835%0.353CS..Hα-helixtrans-58.1-47.9175.8174.60000110.8Y304 F331 D332 P333 K340 I341 F344Y304-V336 HydrophobicContact CE1-CG1 4.2Å; Y304-V336 WeakPolarHBondContact OH-CG1 3.28Å; F331-V336 HydrophobicContact CD1-CG2 3.63Å; F331-V336 HydrophobicContact CE1-CG2 3.66Å; D332-V336 PolarHBondContact O-N 3.44Å; P333-V336 PolarHBondContact O-N 3.25Å; V336-K340 PolarHBondContact O-N 3.12Å; V336-I341 HydrophobicContact CG1-CB 4.16Å; V336-I341 PolarHBondContact O-N 2.97Å; V336-I341 VanDerWaalsContact O-N 3.09Å; V336-F344 HydrophobicContact CG2-CZ 4.24Å
337Q92.9Very high93.9Very high158 Ų15864.6 Ų64.674%0.73834%0.344SS*.Hα-helixtrans-65.6-45.7179.5-172.2178.519.400112.3P333 Q334 W335 N339 K340P333-Q337 WeakPolarHBondContact O-CB 3.42Å; P333-Q337 PolarHBondContact O-N 3.03Å; Q334-Q337 PolarHBondContact O-N 3.19Å; W335-Q337 PolarHBondContact O-N 2.93Å; Q337-N339 VanDerWaalsContact C-N 3.29Å; Q337-N339 PolarHBondContact O-N 3.23Å; Q337-K340 PolarHBondContact O-N 3.1Å; Q337-K340 VanDerWaalsContact O-N 3.1Å
338S96.1Very high93.9Very high94 Ų9468.3 Ų68.366%0.65736%0.36SS*.Hα-helixtrans-65.1-34.1-177.1-60.20000112.3Q334 W335 K340Q334-S338 VanDerWaalsContact O-CB 3.23Å; Q334-S338 WeakPolarHBondContact O-CB 3.47Å; Q334-S338 PolarHBondContact O-N 3.44Å; Q334-S338 PolarHBondContact O-OG 3.33Å; W335-S338 PolarHBondContact O-N 2.92Å; S338-K340 VanDerWaalsContact C-N 3.34Å
339N95.8Very high94.1Very high83 Ų8365.7 Ų65.744%0.44435%0.347SS..THydrogen-bonded Turntrans-90.23.3177.1-67-81.5000113.3W335 Q337 I341W335-N339 VanDerWaalsContact CD1-ND2 3.33Å; W335-N339 PolarHBondContact NE1-ND2 3.04Å; W335-N339 WeakPolarHBondContact O-CB 3.3Å; W335-N339 PolarHBondContact O-N 3.34Å; W335-N339 PolarHBondContact O-ND2 3.01Å; Q337-N339 VanDerWaalsContact C-N 3.29Å; Q337-N339 PolarHBondContact O-N 3.23Å; N339-I341 HydrophobicContact CB-CD1 4Å; N339-I341 HydrophobicContact CB-CG1 3.86Å; N339-I341 PolarHBondContact O-N 2.55Å
340K95Very high94.4Very high176 Ų17663.6 Ų63.677%0.76532%0.324SS*.THydrogen-bonded Turntrans53.239.9179.3-57.7176.9-178.7177.10113.1V336 Q337 S338 L342V336-K340 PolarHBondContact O-N 3.12Å; Q337-K340 PolarHBondContact O-N 3.1Å; Q337-K340 VanDerWaalsContact O-N 3.1Å; S338-K340 VanDerWaalsContact C-N 3.34Å; K340-L342 PolarHBondContact O-N 3.23Å
341I95.2Very high94.9Very high10 Ų1060.5 Ų60.55%0.05130%0.304CS..  trans-76.4123.2-177.6-60.8175.8000109.3Y304 W335 V336 N339 G343 F344Y304-I341 HydrophobicContact CE1-CG2 4.49Å; Y304-I341 PolarHBondContact OH-O 2.75Å; W335-I341 HydrophobicContact CE3-CD1 3.72Å; W335-I341 HydrophobicContact CH2-CD1 3.41Å; W335-I341 VanDerWaalsContact CH2-CD1 3.41Å; W335-I341 HydrophobicContact CZ2-CD1 4.33Å; W335-I341 HydrophobicContact CZ3-CD1 3.05Å; V336-I341 HydrophobicContact CG1-CB 4.16Å; V336-I341 PolarHBondContact O-N 2.97Å; V336-I341 VanDerWaalsContact O-N 3.09Å; N339-I341 HydrophobicContact CB-CD1 4Å; N339-I341 HydrophobicContact CB-CG1 3.86Å; N339-I341 PolarHBondContact O-N 2.55Å; I341-G343 WeakPolarHBondContact CG2-O 2.99Å; I341-F344 HydrophobicContact CD1-CE1 4.23Å; I341-F344 HydrophobicContact CG2-CD1 3.93Å; I341-F344 HydrophobicContact CG2-CE1 3.68Å
342L94.4Very high95.4Very high105 Ų10558.3 Ų58.355%0.5530%0.295SS..  trans-84.9-30.5-177.4-60.1177.2000113.1L306 K309 K340L306-L342 HydrophobicContact CD1-CB 4.08Å; K309-L342 PolarHBondContact NZ-O 3.37Å; K340-L342 PolarHBondContact O-N 3.23Å
343G96.6Very high95.7Very high1 Ų154.8 Ų54.81%0.0128%0.276CS..SBendtrans-174.1167.5-174.100000110.6Y34 Y304 I341Y34-G343 VanDerWaalsContact CE2-C 3.4Å; Y304-G343 CarbonylContact O-C 3.54Å; I341-G343 WeakPolarHBondContact CG2-O 2.99Å
344F97.4Very high96.1Very high0 Ų051.8 Ų51.80%026%0.256CS..SBendtrans-110.5152.7170.6-60.7-36.6000109.6Y34 Y304 F331 V336 I341 H346 V349 S351 D352 I354Y34-F344 PolarHBondContact OH-O 2.91Å; Y304-F344 AromaticContact CD1-CD2 3.98Å; Y304-F344 HydrophobicContact CD1-CD2 3.98Å; Y304-F344 HydrophobicContact CD1-CE2 4.12Å; Y304-F344 HydrophobicContact CD1-CG 4.18Å; Y304-F344 HydrophobicContact CD1-CZ 4.47Å; Y304-F344 HydrophobicContact CG-CD2 4.17Å; Y304-F344 HydrophobicContact CG-CE2 4.25Å; Y304-F344 WeakPolarHBondContact O-CA 3.3Å; Y304-F344 WeakPolarHBondContact O-CB 3.48Å; Y304-F344 PolarHBondContact O-N 3.16Å; F331-F344 HydrophobicContact CD1-CE2 4.49Å; F331-F344 HydrophobicContact CD1-CZ 4.12Å; F331-F344 HydrophobicContact CE1-CE2 4.38Å; F331-F344 AromaticContact CE1-CZ 3.66Å; F331-F344 HydrophobicContact CE1-CZ 3.66Å; F331-F344 HydrophobicContact CE2-CZ 4.46Å; F331-F344 HydrophobicContact CZ-CE2 4.5Å; F331-F344 AromaticContact CZ-CZ 3.86Å; F331-F344 HydrophobicContact CZ-CZ 3.86Å; V336-F344 HydrophobicContact CG2-CZ 4.24Å; I341-F344 HydrophobicContact CD1-CE1 4.23Å; I341-F344 HydrophobicContact CG2-CD1 3.93Å; I341-F344 HydrophobicContact CG2-CE1 3.68Å; F344-H346 HydrophobicContact CD1-CB 3.89Å; F344-H346 HydrophobicContact CE1-CB 4.38Å; F344-V349 HydrophobicContact CB-CG1 4.23Å; F344-V349 HydrophobicContact CD1-CB 3.72Å; F344-V349 HydrophobicContact CD1-CG1 3.86Å; F344-V349 HydrophobicContact CD1-CG2 3.92Å; F344-V349 HydrophobicContact CD2-CG1 3.85Å; F344-V349 HydrophobicContact CE1-CB 3.88Å; F344-V349 HydrophobicContact CE1-CG1 4.11Å; F344-V349 HydrophobicContact CE1-CG2 3.53Å; F344-V349 HydrophobicContact CE2-CG1 4.13Å; F344-V349 HydrophobicContact CG-CB 4.11Å; F344-V349 HydrophobicContact CG-CG1 3.74Å; F344-V349 HydrophobicContact CZ-CB 4.43Å; F344-V349 HydrophobicContact CZ-CG1 4.26Å; F344-V349 HydrophobicContact CZ-CG2 3.93Å; F344-S351 WeakPolarHBondContact CB-O 3.24Å; F344-D352 VanDerWaalsContact O-CB 3.25Å; F344-D352 WeakPolarHBondContact O-CB 3.38Å; F344-I354 HydrophobicContact CD2-CD1 4.36Å; F344-I354 HydrophobicContact CD2-CG1 4.2Å; F344-I354 HydrophobicContact CE2-CD1 3.83Å; F344-I354 HydrophobicContact CE2-CG1 4.03Å
345P97.9Very high96.3Very high1 Ų145.6 Ų45.61%0.00623%0.227CC..SBendcis-65.8160.12.7-1731.8000113L22 Y32 C35 L40 V349L22-P345 HydrophobicContact CD2-CG 3.33Å; Y32-P345 HydrophobicContact CD1-CG 4.41Å; C35-P345 WeakPolarHBondContact CB-O 3.26Å; C35-P345 PolarHBondContact SG-O 2.95Å; C35-P345 VanDerWaalsContact SG-O 3.39Å; L40-P345 HydrophobicContact CD2-CB 4.25Å; L40-P345 HydrophobicContact CD2-CG 3.97Å; P345-V349 CarbonylContact C-O 3.54Å; P345-V349 WeakPolarHBondContact CA-O 3.23Å; P345-V349 WeakPolarHBondContact CB-O 3.38Å
346H97.6Very high96.4Very high45 Ų4542 Ų4221%0.20821%0.214CC..BIsolated β-bridgetrans-139.3157.8178.8-179-92.2000108.3F344 H348 V349F344-H346 HydrophobicContact CD1-CB 3.89Å; F344-H346 HydrophobicContact CE1-CB 4.38Å; H346-H348 AromaticContact CE1-CD2 3.63Å; H346-H348 AromaticContact ND1-CD2 3.81Å; H346-H348 PolarHBondContact ND1-N 2.7Å; H346-H348 PolarHBondContact O-N 3.2Å; H346-V349 HydrophobicContact CB-CB 4.22Å; H346-V349 PolarHBondContact N-O 2.97Å; H346-V349 CarbonylContact O-C 3.59Å; H346-V349 PolarHBondContact O-N 2.87Å
347P97.4Very high96.7Very high19 Ų1942.9 Ų42.912%0.12322%0.218CC..THydrogen-bonded Turntrans-44.3-22171.8-3838.9000117.6P36 W38 A39 Y44P36-P347 HydrophobicContact CG-CG 4.47Å; W38-P347 HydrophobicContact CH2-CB 3.7Å; W38-P347 HydrophobicContact CH2-CG 3.83Å; W38-P347 HydrophobicContact CZ2-CB 4.31Å; W38-P347 HydrophobicContact CZ2-CG 3.94Å; W38-P347 HydrophobicContact CZ3-CB 4.44Å; A39-P347 HydrophobicContact CB-CG 4.05Å; Y44-P347 PolarHBondContact OH-O 2.79Å
348H96.1Very high96.9Very high133 Ų13335.5 Ų35.562%0.61618%0.184SC*.THydrogen-bonded Turntrans-114.6-1.2178.6-58-57.3000114.2W335 H346W335-H348 HydrophobicContact CH2-CB 4.11Å; W335-H348 HydrophobicContact CZ2-CB 4.33Å; H346-H348 AromaticContact CE1-CD2 3.63Å; H346-H348 AromaticContact ND1-CD2 3.81Å; H346-H348 PolarHBondContact ND1-N 2.7Å; H346-H348 PolarHBondContact O-N 3.2Å
349V96.9Very high96.9Very high8 Ų834.8 Ų34.85%0.04817%0.17CC..BIsolated β-bridgetrans-137.2114.5-177.6-174.60000108.7F331 W335 F344 P345 H346F331-V349 HydrophobicContact CE2-CG2 4.23Å; F331-V349 HydrophobicContact CZ-CG2 3.81Å; W335-V349 HydrophobicContact CH2-CG2 4.38Å; W335-V349 HydrophobicContact CZ3-CG2 4.39Å; F344-V349 HydrophobicContact CB-CG1 4.23Å; F344-V349 HydrophobicContact CD1-CB 3.72Å; F344-V349 HydrophobicContact CD1-CG1 3.86Å; F344-V349 HydrophobicContact CD1-CG2 3.92Å; F344-V349 HydrophobicContact CD2-CG1 3.85Å; F344-V349 HydrophobicContact CE1-CB 3.88Å; F344-V349 HydrophobicContact CE1-CG1 4.11Å; F344-V349 HydrophobicContact CE1-CG2 3.53Å; F344-V349 HydrophobicContact CE2-CG1 4.13Å; F344-V349 HydrophobicContact CG-CB 4.11Å; F344-V349 HydrophobicContact CG-CG1 3.74Å; F344-V349 HydrophobicContact CZ-CB 4.43Å; F344-V349 HydrophobicContact CZ-CG1 4.26Å; F344-V349 HydrophobicContact CZ-CG2 3.93Å; P345-V349 CarbonylContact C-O 3.54Å; P345-V349 WeakPolarHBondContact CA-O 3.23Å; P345-V349 WeakPolarHBondContact CB-O 3.38Å; H346-V349 HydrophobicContact CB-CB 4.22Å; H346-V349 PolarHBondContact N-O 2.97Å; H346-V349 CarbonylContact O-C 3.59Å; H346-V349 PolarHBondContact O-N 2.87Å
350A97.3Very high97Very high2 Ų231 Ų312%0.01715%0.149CC..  trans-91-7.6-160.500000115.5R45 L48 I49R45-A350 HydrophobicContact CB-CB 4.29Å; R45-A350 VanDerWaalsContact CD-O 3.29Å; R45-A350 WeakPolarHBondContact CD-O 3.29Å; R45-A350 PolarHBondContact NH1-O 2.06Å; L48-A350 HydrophobicContact CB-CB 3.57Å; L48-A350 HydrophobicContact CD1-CB 4.19Å; I49-A350 HydrophobicContact CD1-CB 4.42Å; I49-A350 HydrophobicContact CG1-CB 3.67Å
351S98.4Very high97.1Very high0 Ų023 Ų230%012%0.116CC..SBendtrans-129.6157.7174.6-178.40000108.5Y19 N20 F344 H353Y19-S351 VanDerWaalsContact OH-CB 3.29Å; Y19-S351 WeakPolarHBondContact OH-CB 3.44Å; N20-S351 WeakPolarHBondContact O-CB 3.38Å; N20-S351 PolarHBondContact O-OG 3.44Å; F344-S351 WeakPolarHBondContact CB-O 3.24Å; S351-H353 WeakPolarHBondContact CB-O 3.46Å; S351-H353 PolarHBondContact OG-N 3.46Å; S351-H353 VanDerWaalsContact OG-N 3.09Å
352D98.1Very high97.1Very high9 Ų922.9 Ų22.95%0.04812%0.116CC..SBendtrans-74.6-13.5165.758.3-31.8000113.2Y32 N303 Y304 T305 F344Y32-D352 HydrophobicContact CE1-CB 3.74Å; Y32-D352 PolarHBondContact OH-OD2 2.71Å; N303-D352 WeakPolarHBondContact CA-O 3.34Å; N303-D352 PolarHBondContact ND2-OD2 2.74Å; Y304-D352 PolarHBondContact N-O 3.45Å; T305-D352 HydrophobicContact CG2-CB 3.79Å; F344-D352 VanDerWaalsContact O-CB 3.25Å; F344-D352 WeakPolarHBondContact O-CB 3.38Å
353H98.3Very high97.1Very high6 Ų619.8 Ų19.83%0.02810%0.099CC..BIsolated β-bridgetrans-94.3154.8169-66.7-113.5000112.2Y19 N20 D238 T302 N303 D313 S351Y19-H353 WeakPolarHBondContact CE2-O 3.4Å; N20-H353 HydrophobicContact CB-CB 4.01Å; D238-H353 IonicContact OD2-CE1 3.72Å; D238-H353 PolarHBondContact OD2-CE1 3.12Å; D238-H353 IonicContact OD2-NE2 3.83Å; T302-H353 CarbonylContact O-C 3.57Å; T302-H353 WeakPolarHBondContact O-CA 2.96Å; N303-H353 PolarHBondContact ND2-CD2 2.62Å; N303-H353 PolarHBondContact ND2-NE2 3.29Å; D313-H353 IonicContact OD1-CE1 3.62Å; D313-H353 IonicContact OD1-ND1 3.52Å; D313-H353 PolarHBondContact OD1-ND1 3.35Å; D313-H353 IonicContact OD2-CE1 3.9Å; D313-H353 IonicContact OD2-CG 3.26Å; D313-H353 IonicContact OD2-ND1 3.18Å; D313-H353 PolarHBondContact OD2-ND1 2.83Å; S351-H353 WeakPolarHBondContact CB-O 3.46Å; S351-H353 PolarHBondContact OG-N 3.46Å; S351-H353 VanDerWaalsContact OG-N 3.09Å
354I96.5Very high96.9Very high15 Ų1520.7 Ų20.78%0.07711%0.105CC..  trans-109127.7176.6-56.9175.1000107.2F301 T302 F331 F344 I356F301-I354 HydrophobicContact CD2-CD1 3.44Å; F301-I354 VanDerWaalsContact CD2-CD1 3.44Å; F301-I354 HydrophobicContact CE2-CD1 3.37Å; T302-I354 PolarHBondContact O-N 3.18Å; F331-I354 HydrophobicContact CB-CD1 3.73Å; F331-I354 HydrophobicContact CB-CG2 4.18Å; F331-I354 HydrophobicContact CD2-CD1 4.33Å; F331-I354 HydrophobicContact CD2-CG2 4.08Å; F331-I354 HydrophobicContact CG-CD1 4.09Å; F344-I354 HydrophobicContact CD2-CD1 4.36Å; F344-I354 HydrophobicContact CD2-CG1 4.2Å; F344-I354 HydrophobicContact CE2-CD1 3.83Å; F344-I354 HydrophobicContact CE2-CG1 4.03Å; I354-I356 PolarHBondContact O-N 3.11Å
355P96.8Very high96.5Very high6 Ų622.2 Ų22.24%0.03911%0.114CC..  trans-61.2133.5177.822.6-31.2000111.1L17 Y19 E52 Y56L17-P355 HydrophobicContact CD1-CB 3.78Å; Y19-P355 HydrophobicContact CD1-CB 4.34Å; Y19-P355 HydrophobicContact CD2-CB 3.98Å; Y19-P355 HydrophobicContact CD2-CG 4.47Å; Y19-P355 HydrophobicContact CE2-CB 4.48Å; Y19-P355 HydrophobicContact CE2-CG 4.49Å; Y19-P355 HydrophobicContact CG-CB 3.91Å; E52-P355 HydrophobicContact CG-CG 4.19Å; E52-P355 WeakPolarHBondContact OE1-CG 3.33Å; Y56-P355 HydrophobicContact CE2-CB 3.88Å; Y56-P355 HydrophobicContact CE2-CG 3.5Å; Y56-P355 WeakPolarHBondContact OH-CG 3.2Å
356I97.5Very high96Very high4 Ų425.7 Ų25.72%0.02114%0.136CC..EExtended strand (participates in β ladder)trans-106.9142.517158.9175.3000109.5C18 I299 T302 D313 I315 I354C18-I356 HydrophobicContact CB-CD1 4.21Å; C18-I356 HydrophobicContact CB-CG1 3.79Å; C18-I356 PolarHBondContact N-O 3.35Å; C18-I356 PolarHBondContact O-N 3.14Å; I299-I356 HydrophobicContact CD1-CG2 4.27Å; T302-I356 HydrophobicContact CG2-CG2 3.66Å; D313-I356 HydrophobicContact CB-CD1 4Å; D313-I356 WeakPolarHBondContact O-CD1 3.05Å; I315-I356 HydrophobicContact CD1-CB 4.38Å; I315-I356 HydrophobicContact CD1-CD1 4.1Å; I315-I356 HydrophobicContact CD1-CG1 3.85Å; I315-I356 HydrophobicContact CG1-CD1 3.85Å; I315-I356 HydrophobicContact CG1-CG1 4.08Å; I354-I356 PolarHBondContact O-N 3.11Å
357M97.6Very high95.4Very high26 Ų2628 Ų2813%0.12815%0.146CC..EExtended strand (participates in β ladder)trans-143.3144-176.9-176.8-176.3178.900110.9T15 V16 L17 Y56 A58 I327 L328T15-M357 HydrophobicContact CG2-CE 3.69Å; V16-M357 CarbonylContact O-C 3.59Å; V16-M357 WeakPolarHBondContact O-CA 3.36Å; V16-M357 VanDerWaalsContact O-CG 3.28Å; V16-M357 WeakPolarHBondContact O-CG 2.9Å; L17-M357 HydrophobicContact CD1-CB 3.96Å; L17-M357 HydrophobicContact CD1-CG 4.43Å; Y56-M357 HydrophobicContact CD1-SD 4.05Å; Y56-M357 HydrophobicContact CG-SD 4.21Å; Y56-M357 WeakPolarHBondContact O-CE 3.19Å; A58-M357 HydrophobicContact CB-CE 3.86Å; I327-M357 CarbonylContact C-O 3.4Å; I327-M357 WeakPolarHBondContact CA-O 3.45Å; L328-M357 HydrophobicContact CB-CB 3.85Å; L328-M357 HydrophobicContact CD2-CB 4.24Å; L328-M357 PolarHBondContact N-O 2.97Å
358A97.6Very high94.9Very high3 Ų327.9 Ų27.93%0.02514%0.144CC..EExtended strand (participates in β ladder)trans-138.1149.4177.800000111.4T15 V16 A293 I315 G326 I327 Y360T15-A358 CarbonylContact C-O 3.59Å; T15-A358 WeakPolarHBondContact CA-O 3.1Å; V16-A358 HydrophobicContact CG1-CB 4.28Å; V16-A358 PolarHBondContact N-O 3.01Å; V16-A358 PolarHBondContact O-N 2.86Å; A293-A358 HydrophobicContact CB-CB 3.84Å; I315-A358 HydrophobicContact CD1-CB 4.3Å; G326-A358 WeakPolarHBondContact O-CA 3.07Å; I327-A358 HydrophobicContact CG2-CB 4.1Å; A358-Y360 HydrophobicContact CB-CD2 4.3Å; A358-Y360 HydrophobicContact CB-CE2 3.56Å
359Q97.6Very high93.8Very high78 Ų7832 Ų3236%0.36415%0.154SC..EExtended strand (participates in β ladder)trans-107.3134.4171.6-170-178.942.700109.8T15 L325 G326T15-Q359 HydrophobicContact CG2-CB 3.98Å; T15-Q359 HydrophobicContact CG2-CG 3.87Å; L325-Q359 HydrophobicContact CB-CB 4.34Å; L325-Q359 HydrophobicContact CB-CG 4.32Å; L325-Q359 HydrophobicContact CD1-CG 4.22Å; L325-Q359 PolarHBondContact N-O 3.11Å; G326-Q359 PolarHBondContact O-N 3.47Å
360Y97.6Very high92Very high3 Ų340.4 Ų40.41%0.01219%0.193CC..EExtended strand (participates in β ladder)trans-125.1144.2178.7-67.6-85.4000111.7T13 F14 V16 L234 A293 I315 A317 L322 A323 R324 A358T13-Y360 VanDerWaalsContact CA-O 3.24Å; T13-Y360 WeakPolarHBondContact CA-O 3.34Å; F14-Y360 PolarHBondContact N-O 2.8Å; F14-Y360 PolarHBondContact O-N 3.48Å; V16-Y360 HydrophobicContact CG1-CD2 4.01Å; V16-Y360 HydrophobicContact CG1-CE2 3.7Å; L234-Y360 HydrophobicContact CD2-CD2 4.29Å; L234-Y360 HydrophobicContact CD2-CE2 3.87Å; A293-Y360 WeakPolarHBondContact CB-OH 3.38Å; I315-Y360 HydrophobicContact CG2-CE2 4.19Å; A317-Y360 HydrophobicContact CB-CD1 4.36Å; A317-Y360 HydrophobicContact CB-CE1 3.51Å; A317-Y360 HydrophobicContact CB-CE2 4.48Å; A317-Y360 WeakPolarHBondContact CB-OH 3.45Å; L322-Y360 HydrophobicContact CB-CD1 3.8Å; L322-Y360 HydrophobicContact CB-CE1 4.41Å; L322-Y360 HydrophobicContact CB-CG 4.33Å; A323-Y360 CarbonylContact O-C 3.57Å; A323-Y360 WeakPolarHBondContact O-CA 3.35Å; R324-Y360 HydrophobicContact CB-CD1 4.07Å; R324-Y360 HydrophobicContact CB-CE1 3.75Å; R324-Y360 HydrophobicContact CG-CE1 4.14Å; A358-Y360 HydrophobicContact CB-CD2 4.3Å; A358-Y360 HydrophobicContact CB-CE2 3.56Å
361A96Very high89.9Confident8 Ų844 Ų447%0.06621%0.21CC..EExtended strand (participates in β ladder)trans-94.1132.8159.400000109.7I11 A12 T13 L322 A323 L325I11-A361 HydrophobicContact CG2-CB 3.52Å; A12-A361 CarbonylContact O-C 3.55Å; A12-A361 VanDerWaalsContact O-CA 3.32Å; A12-A361 WeakPolarHBondContact O-CA 3.48Å; T13-A361 HydrophobicContact CG2-CB 4.31Å; L322-A361 WeakPolarHBondContact CA-O 3.4Å; A323-A361 HydrophobicContact CB-CB 4.32Å; A323-A361 PolarHBondContact N-O 3.08Å; A323-A361 PolarHBondContact O-N 3.28Å; L325-A361 HydrophobicContact CD1-CB 4.04Å; L325-A361 HydrophobicContact CD2-CB 3.94Å; L325-A361 HydrophobicContact CG-CB 4.09Å
362I95.8Very high87.3Confident9 Ų949.4 Ų49.45%0.04625%0.245CC..EExtended strand (participates in β ladder)trans-79.9121.8175-57.4161.7000108A12 F14 I159 V180 P232 L322 P364A12-I362 HydrophobicContact CB-CB 4.16Å; A12-I362 HydrophobicContact CB-CD1 4.19Å; A12-I362 PolarHBondContact O-N 2.89Å; F14-I362 HydrophobicContact CD1-CD1 3.83Å; F14-I362 HydrophobicContact CD1-CG1 3.77Å; F14-I362 HydrophobicContact CE1-CD1 4.02Å; F14-I362 HydrophobicContact CE1-CG1 3.62Å; I159-I362 HydrophobicContact CD1-CD1 3.86Å; I159-I362 HydrophobicContact CD1-CG2 4.37Å; I159-I362 HydrophobicContact CG1-CD1 4.31Å; I159-I362 HydrophobicContact CG2-CD1 4.42Å; V180-I362 HydrophobicContact CB-CG2 4.11Å; V180-I362 HydrophobicContact CG1-CG2 3.94Å; V180-I362 HydrophobicContact CG2-CB 4.4Å; V180-I362 HydrophobicContact CG2-CD1 4.27Å; V180-I362 HydrophobicContact CG2-CG2 4.21Å; P232-I362 HydrophobicContact CG-CG2 4.42Å; L322-I362 HydrophobicContact CD2-CG1 4.11Å; I362-P364 WeakPolarHBondContact O-CD 3.11Å
363I94.1Very high84.5Confident39 Ų3957 Ų5720%0.228%0.284CS..PPolyproline II helixtrans-83.4119.5177.4-55.8171.4000107.6S321 A323 H367 Q368S321-I363 PolarHBondContact O-N 2.66Å; A323-I363 HydrophobicContact CB-CD1 4.14Å; A323-I363 HydrophobicContact CB-CG1 4.19Å; I363-H367 HydrophobicContact CG2-CB 4.05Å; I363-Q368 HydrophobicContact CB-CG 4.06Å; I363-Q368 HydrophobicContact CG2-CG 3.7Å; I363-Q368 PolarHBondContact O-NE2 2.8Å
364P92.2Very high81.7Confident21 Ų2165 Ų6514%0.13632%0.322CS..PPolyproline II helixtrans-59.2144.3179-21.832.4000111.8N177 D178 V180 I362 T366 H367 Q368N177-P364 VanDerWaalsContact O-CB 3.25Å; N177-P364 WeakPolarHBondContact O-CB 3.45Å; D178-P364 WeakPolarHBondContact O-CG 3.31Å; V180-P364 HydrophobicContact CG1-CB 3.97Å; V180-P364 HydrophobicContact CG1-CG 3.89Å; I362-P364 WeakPolarHBondContact O-CD 3.11Å; P364-T366 PolarHBondContact O-N 3.44Å; P364-H367 PolarHBondContact O-N 3.13Å; P364-Q368 WeakPolarHBondContact O-CG 3.22Å; P364-Q368 PolarHBondContact O-N 3.45Å
365T89.6Confident78.6Confident31 Ų3173 Ų7319%0.1936%0.359CS..THydrogen-bonded Turntrans-56.5-27.3-17151.90000114Q230Q230-T365 HydrophobicContact CB-CG2 4.24Å; Q230-T365 PolarHBondContact NE2-O 2.84Å
366T86.5Confident75.7Confident75 Ų7578.1 Ų78.146%0.4640%0.402SS..THydrogen-bonded Turntrans-76.8-23.1176.162.10000113.9N177 P364N177-T366 HydrophobicContact CB-CG2 4.09Å; N177-T366 PolarHBondContact O-OG1 3.15Å; P364-T366 PolarHBondContact O-N 3.44Å
367H86.4Confident72.5Confident93 Ų9380.9 Ų80.943%0.43143%0.431SS..THydrogen-bonded Turntrans-98.3-9.4-179.8-63.5-55.9000113.3D178 I363 P364 R369D178-H367 IonicContact OD1-CD2 3.31Å; D178-H367 IonicContact OD1-CE1 3.7Å; D178-H367 IonicContact OD1-NE2 2.63Å; D178-H367 PolarHBondContact OD1-NE2 2.84Å; I363-H367 HydrophobicContact CG2-CB 4.05Å; P364-H367 PolarHBondContact O-N 3.13Å; H367-R369 PolarHBondContact O-N 3.08Å
368Q85.3Confident69.4Low17 Ų1785.8 Ų85.88%0.07947%0.465CS..SBendtrans-65.7130.2175.1-64.9172.5-3.100108.9Q230 Q320 I363 P364 Q370Q230-Q368 VanDerWaalsContact CG-OE1 3.28Å; Q230-Q368 PolarHBondContact O-NE2 3.32Å; Q230-Q368 PolarHBondContact O-OE1 3.48Å; Q320-Q368 WeakPolarHBondContact O-CG 3.25Å; I363-Q368 HydrophobicContact CB-CG 4.06Å; I363-Q368 HydrophobicContact CG2-CG 3.7Å; I363-Q368 PolarHBondContact O-NE2 2.8Å; P364-Q368 WeakPolarHBondContact O-CG 3.22Å; P364-Q368 PolarHBondContact O-N 3.45Å; Q368-Q370 PolarHBondContact O-N 2.69Å
369R73.3Confident66.4Low219 Ų21990.7 Ų90.783%0.82651%0.506SS*.  trans-62.2112.6-176.9-76.9-174.9-106.2175-1.1109.8H367H367-R369 PolarHBondContact O-N 3.08Å
370Q59Low63.3Low184 Ų18491.8 Ų91.886%0.8653%0.528SS*.PPolyproline II helixtrans-63.6134.3165.6-68.7-173.80.900108.7Q368Q368-Q370 PolarHBondContact O-N 2.69Å
371Q54.4Low60Low78 Ų7895 Ų9536%0.36456%0.561SS.*PPolyproline II helixtrans-90.9145.3176.3-67.3173.123.700110.1R289 L373R289-Q371 VanDerWaalsContact NH1-OE1 3.12Å; Q371-L373 PolarHBondContact O-N 3.27Å
372P43.2Very low56.8Low113 Ų113101.5 Ų101.573%0.73460%0.6SS**PPolyproline II helixtrans-56.6136.4161.1-13.226.4000108.5Q374P372-Q374 PolarHBondContact O-N 3.15Å; P372-Q374 VanDerWaalsContact O-N 3.09Å
373L40.1Very low53.7Low168 Ų168109 Ų10988%0.8864%0.639SS**PPolyproline II helixtrans-48.9119.9164.1-74.5155.1000107.4Q371 Q375Q371-L373 PolarHBondContact O-N 3.27Å; L373-Q375 VanDerWaalsContact C-N 3.33Å; L373-Q375 PolarHBondContact O-N 2.86Å
374Q40Very low50.7Low174 Ų174110.6 Ų110.681%0.81367%0.665SS**  trans-61.998.1175.6-86.9175.2-24.400108.3P372P372-Q374 PolarHBondContact O-N 3.15Å; P372-Q374 VanDerWaalsContact O-N 3.09Å
375Q30.6Very low47.6Very low183 Ų183112.8 Ų112.886%0.85569%0.691SS**  trans-68.7125.8157.2-72.8-174.2-1.700106.8L373 G377L373-Q375 VanDerWaalsContact C-N 3.33Å; L373-Q375 PolarHBondContact O-N 2.86Å; Q375-G377 PolarHBondContact O-N 3.46Å
376A36.7Very low44.5Very low115 Ų115115.2 Ų115.295%0.9572%0.722SS**  trans-58.7107.617300000109.2
377G30.2Very low41.9Very low61 Ų61121.3 Ų121.363%0.62974%0.743SS**  trans-130.4151.3175.200000110Q375Q375-G377 PolarHBondContact O-N 3.46Å
378P31Very low39.2Very low130 Ų130122.3 Ų122.384%0.84476%0.758SS**PPolyproline II helixtrans-71149.9-158.329.6-33.9000112.7A380P378-A380 PolarHBondContact O-N 3.05Å
379A35.3Very low36.6Very low106 Ų106127.2 Ų127.288%0.87679%0.794SS**PPolyproline II helixtrans-49.4117.1178.500000111.9
380A31.6Very low34.7Very low101 Ų101122.8 Ų122.884%0.83579%0.791SS**PPolyproline II helixtrans-76136.4169.500000109.6P378P378-A380 PolarHBondContact O-N 3.05Å
381G28.3Very low33.4Very low69 Ų69120 Ų12071%0.71179%0.789SS**PPolyproline II helixtrans-63146.9-164.200000115.7I383G381-I383 PolarHBondContact O-N 3.49Å
382V30.1Very low32.8Very low145 Ų145122.4 Ų122.488%0.87981%0.814SS**  trans-60.5115.4168.7178.70000109.1
383I29.4Very low32.2Very low167 Ų167120.8 Ų120.886%0.85682%0.819SS**  trans-102.1110.1161.8-51.9180000106.3G381 G385G381-I383 PolarHBondContact O-N 3.49Å; I383-G385 PolarHBondContact O-N 3.48Å
384G32.2Very low31.7Very low73 Ų73117.5 Ų117.575%0.75382%0.815SS**  trans-68.1125.3179.900000111.9
385G25.8Very low31.4Very low67 Ų67116.8 Ų116.869%0.69181%0.812SS**  trans-123.9108.4160.800000107.7I383I383-G385 PolarHBondContact O-N 3.48Å
386G26Very low31.5Very low82 Ų82113.5 Ų113.585%0.84581%0.807SS**PPolyproline II helixtrans-67.3133.8177.500000111.2
387F30.8Very low31.3Very low202 Ų202116.7 Ų116.789%0.88680%0.8SS**PPolyproline II helixtrans-78.1138.5167.1-79.3-87.1000109.8
388P29.4Very low31.8Very low115 Ų115117.4 Ų117.475%0.74779%0.789SS**PPolyproline II helixtrans-71.8138174.426.1-26.4000110.7T390P388-T390 PolarHBondContact O-N 3.32Å
389S31.1Very low32.3Very low120 Ų120121.6 Ų121.684%0.83979%0.788SS**PPolyproline II helixtrans-61.9123.9175.949.30000111.9
390T33.2Very low32.6Very low125 Ų125118.9 Ų118.977%0.76776%0.761SS**PPolyproline II helixtrans-78152.216944.20000112P388P388-T390 PolarHBondContact O-N 3.32Å
391P32.3Very low32.6Very low126 Ų126119.8 Ų119.882%0.81876%0.758SS**PPolyproline II helixtrans-70.4141.4-175.7-10.326.6000112.2G393P391-G393 PolarHBondContact O-N 3.28Å
392S41.3Very low32.8Very low128 Ų128122.4 Ų122.490%0.89576%0.76SS**SBendtrans-60.1116.4177.552.50000112.8
393G31Very low33Very low80 Ų80121.2 Ų121.283%0.82575%0.753SS**  trans-1621.8170.700000115.8P391P391-G393 PolarHBondContact O-N 3.28Å
394A30.6Very low33.2Very low98 Ų98118.5 Ų118.581%0.8175%0.747SS**SBendtrans-98.7129.1173.700000109.9
395Q31.7Very low33.3Very low160 Ų160121.3 Ų121.375%0.74875%0.747SS**  trans-61.4147.6174.2-71.9-175-1200110.8F397Q395-F397 PolarHBondContact O-N 2.78Å
396P34.7Very low33.8Very low114 Ų114124.9 Ų124.974%0.7475%0.751SS**G310 helixtrans-72.73.3-172.2-14.430.2000115.8L398P396-L398 PolarHBondContact O-N 3.05Å
397F32.3Very low34.3Very low182 Ų182128 Ų12880%0.79874%0.744SS**G310 helixtrans-89.46.8-170.2-77.8-79.3000115.4Q395Q395-F397 PolarHBondContact O-N 2.78Å
398L39.1Very low34.6Very low76 Ų76122.3 Ų122.340%0.39873%0.733SS.*G310 helixtrans-128.222.5-177.2-68.6165000113.1P196 F308 P396 C400P196-L398 HydrophobicContact CB-CD2 4.38Å; P196-L398 HydrophobicContact CG-CD2 4.19Å; F308-L398 HydrophobicContact CD2-CD1 4.15Å; F308-L398 HydrophobicContact CD2-CD2 4.46Å; P396-L398 PolarHBondContact O-N 3.05Å; L398-C400 WeakPolarHBondContact CA-OXT 3.32Å
399R43.2Very low35Very low218 Ų218122.9 Ų122.982%0.82373%0.732SS**  trans-10538.8169.9-76-169.3173.5-161.6-2.9111.8
400C39.7Very low35.4Very low48 Ų48123.2 Ų123.232%0.32472%0.722SS.*  -134.50106.1-85.70000105.1P196 C199 L398P196-C400 CarbonylContact C-O 3.56Å; P196-C400 WeakPolarHBondContact CA-O 3.15Å; P196-C400 WeakPolarHBondContact CB-OXT 3.42Å; P196-C400 CarbonylContact O-C 3.01Å; P196-C400 WeakPolarHBondContact O-CB 3.44Å; C199-C400 HydrophobicContact CB-CB 3.5Å; C199-C400 VanDerWaalsContact CB-CB 3.5Å; C199-C400 WeakPolarHBondContact CB-SG 3.27Å; C199-C400 WeakPolarHBondContact SG-CB 3.28Å; C199-C400 CovalentContact SG-SG 2.06Å; C199-C400 PolarHBondContact SG-SG 3.36Å; L398-C400 WeakPolarHBondContact CA-OXT 3.32Å

Retrieved 400 of 400 residues in 267.9 ms (Link to these results)