A0A061AKV1_CAEEL Loading...

UDP-glucuronosyltransferase

AlphaFold DB , UniProt , Accession A0A061AKV1, Species CAEEL (Caenorhabditis elegans), Gene ugt-21, Length 534 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M65.5Low76.6Confident201 Ų201129.3 Ų129.399%0.9962%0.622SS**  0-60.70-91.5167.456.500114.4K3 L4 L5M1-K3 PolarHBondContact O-N 3.31Å; M1-L4 PolarHBondContact O-N 3.27Å; M1-L4 VanDerWaalsContact O-N 3.11Å; M1-L5 PolarHBondContact O-N 3.33Å
2R75Confident75.7Confident214 Ų214122.8 Ų122.881%0.80860%0.6SS**Hα-helixtrans-56.2-40.5-173.6-134.5176.4-175.2-178.41.2115.2L5 N6R2-L5 PolarHBondContact O-N 3.26Å; R2-N6 PolarHBondContact O-N 3.24Å; R2-N6 PolarHBondContact O-OD1 3.43Å
3K76.7Confident74.8Confident178 Ų178121.3 Ų121.377%0.77460%0.595SS**Hα-helixtrans-66.9-39.7175.5-74.1-176.1176.5-177.50113.4M1 N6 I7M1-K3 PolarHBondContact O-N 3.31Å; K3-N6 PolarHBondContact O-N 2.98Å; K3-I7 WeakPolarHBondContact O-CG1 3.31Å; K3-I7 PolarHBondContact O-N 3.32Å
4L80.9Confident73.6Confident127 Ų127121 Ų12167%0.66560%0.595SS**Hα-helixtrans-66.7-40.3175.8-83.9152.3000111.3M1 I7 F8M1-L4 PolarHBondContact O-N 3.27Å; M1-L4 VanDerWaalsContact O-N 3.11Å; L4-I7 PolarHBondContact O-N 3.24Å; L4-F8 WeakPolarHBondContact O-CB 3.49Å; L4-F8 PolarHBondContact O-N 3.41Å
5L82.7Confident72.3Confident101 Ų101119 Ų11953%0.52960%0.598SS.*Hα-helixtrans-62.6-42.9174.9-174.167.6000111.6M1 R2 F8 I9M1-L5 PolarHBondContact O-N 3.33Å; R2-L5 PolarHBondContact O-N 3.26Å; L5-F8 PolarHBondContact O-N 3.01Å; L5-I9 HydrophobicContact CD1-CD1 4.31Å; L5-I9 HydrophobicContact CD2-CD1 4.46Å; L5-I9 HydrophobicContact CG-CD1 3.87Å; L5-I9 HydrophobicContact CG-CG1 4.48Å; L5-I9 WeakPolarHBondContact O-CB 3.17Å; L5-I9 VanDerWaalsContact O-CG1 3.23Å; L5-I9 WeakPolarHBondContact O-CG1 3.24Å; L5-I9 PolarHBondContact O-N 3.05Å
6N82.6Confident71.1Confident99 Ų99118.5 Ų118.553%0.52961%0.607SS.*Hα-helixtrans-65.3-39.7177-71-3.4000112.5R2 K3 L10R2-N6 PolarHBondContact O-N 3.24Å; R2-N6 PolarHBondContact O-OD1 3.43Å; K3-N6 PolarHBondContact O-N 2.98Å; N6-L10 VanDerWaalsContact O-CB 3.27Å; N6-L10 WeakPolarHBondContact O-CB 3.37Å; N6-L10 PolarHBondContact O-N 3.44Å
7I80.6Confident70.5Confident105 Ų105117.7 Ų117.754%0.53861%0.609SS.*Hα-helixtrans-64.4-44.7174-68.5166.9000109.8K3 L4 I9 L10 T11K3-I7 WeakPolarHBondContact O-CG1 3.31Å; K3-I7 PolarHBondContact O-N 3.32Å; L4-I7 PolarHBondContact O-N 3.24Å; I7-I9 PolarHBondContact O-N 3.06Å; I7-L10 PolarHBondContact O-N 2.86Å; I7-T11 HydrophobicContact CG2-CG2 4.29Å; I7-T11 WeakPolarHBondContact O-CB 3.17Å; I7-T11 WeakPolarHBondContact O-CG2 3.38Å; I7-T11 PolarHBondContact O-N 3.48Å; I7-T11 PolarHBondContact O-OG1 2.9Å
8F80Confident70.2Confident144 Ų144115.2 Ų115.263%0.63260%0.603SS**Hα-helixtrans-61.1-46.5178.7-149.1-87.4000111.3L4 L5 L10 T11 S12L4-F8 WeakPolarHBondContact O-CB 3.49Å; L4-F8 PolarHBondContact O-N 3.41Å; L5-F8 PolarHBondContact O-N 3.01Å; F8-L10 PolarHBondContact O-N 2.69Å; F8-T11 WeakPolarHBondContact CA-OG1 3.36Å; F8-T11 PolarHBondContact O-N 3.28Å; F8-T11 PolarHBondContact O-OG1 3.2Å; F8-S12 WeakPolarHBondContact O-CB 3.21Å; F8-S12 PolarHBondContact O-N 3.29Å; F8-S12 PolarHBondContact O-OG 3.36Å
9I78.6Confident71.2Confident80 Ų80112 Ų11241%0.4159%0.592SS.*Hα-helixtrans-60.4-45.6174.5-69.3167.1000110.6L5 I7 S12 I13L5-I9 HydrophobicContact CD1-CD1 4.31Å; L5-I9 HydrophobicContact CD2-CD1 4.46Å; L5-I9 HydrophobicContact CG-CD1 3.87Å; L5-I9 HydrophobicContact CG-CG1 4.48Å; L5-I9 WeakPolarHBondContact O-CB 3.17Å; L5-I9 VanDerWaalsContact O-CG1 3.23Å; L5-I9 WeakPolarHBondContact O-CG1 3.24Å; L5-I9 PolarHBondContact O-N 3.05Å; I7-I9 PolarHBondContact O-N 3.06Å; I9-S12 PolarHBondContact O-N 3.14Å; I9-I13 HydrophobicContact CG2-CD1 3.55Å; I9-I13 HydrophobicContact CG2-CG1 4.27Å; I9-I13 WeakPolarHBondContact O-CB 3.38Å; I9-I13 WeakPolarHBondContact O-CG1 3.33Å; I9-I13 PolarHBondContact O-N 2.95Å
10L71.4Confident72.5Confident107 Ų107108.2 Ų108.256%0.5657%0.569SS**Hα-helixtrans-64.8-43.2179.4-160.379.8000111.4N6 I7 F8 I13 I14N6-L10 VanDerWaalsContact O-CB 3.27Å; N6-L10 WeakPolarHBondContact O-CB 3.37Å; N6-L10 PolarHBondContact O-N 3.44Å; I7-L10 PolarHBondContact O-N 2.86Å; F8-L10 PolarHBondContact O-N 2.69Å; L10-I13 PolarHBondContact O-N 3.09Å; L10-I14 HydrophobicContact CD2-CD1 4.31Å; L10-I14 HydrophobicContact CG-CD1 4Å; L10-I14 WeakPolarHBondContact O-CB 3.17Å; L10-I14 WeakPolarHBondContact O-CD1 3.44Å; L10-I14 WeakPolarHBondContact O-CG1 3.16Å; L10-I14 PolarHBondContact O-N 2.96Å
11T68.9Low73.7Confident66 Ų66105.2 Ų105.241%0.40555%0.552SS.*Hα-helixtrans-66-37.2174.750.50000111.7I7 F8 I14 S15I7-T11 HydrophobicContact CG2-CG2 4.29Å; I7-T11 WeakPolarHBondContact O-CB 3.17Å; I7-T11 WeakPolarHBondContact O-CG2 3.38Å; I7-T11 PolarHBondContact O-N 3.48Å; I7-T11 PolarHBondContact O-OG1 2.9Å; F8-T11 WeakPolarHBondContact CA-OG1 3.36Å; F8-T11 PolarHBondContact O-N 3.28Å; F8-T11 PolarHBondContact O-OG1 3.2Å; T11-I14 PolarHBondContact O-N 3.13Å; T11-S15 WeakPolarHBondContact O-CB 3.25Å; T11-S15 PolarHBondContact O-N 3.47Å; T11-S15 PolarHBondContact O-OG 2.91Å
12S65.9Low75.3Confident51 Ų5195.7 Ų95.736%0.35750%0.504SS..Hα-helixtrans-66.7-40.2174.5-64.60000111.7F8 I9 S15 C16F8-S12 WeakPolarHBondContact O-CB 3.21Å; F8-S12 PolarHBondContact O-N 3.29Å; F8-S12 PolarHBondContact O-OG 3.36Å; I9-S12 PolarHBondContact O-N 3.14Å; S12-S15 PolarHBondContact O-N 3.44Å; S12-C16 WeakPolarHBondContact O-CB 3.25Å; S12-C16 PolarHBondContact O-N 3.45Å; S12-C16 PolarHBondContact O-SG 2.9Å; S12-C16 VanDerWaalsContact O-SG 3.37Å
13I63.3Low76.4Confident104 Ų10485.5 Ų85.553%0.53347%0.466SS..Hα-helixtrans-66-43.2175.4-67.9165.8000110.7I9 L10 S15 C16I9-I13 HydrophobicContact CG2-CD1 3.55Å; I9-I13 HydrophobicContact CG2-CG1 4.27Å; I9-I13 WeakPolarHBondContact O-CB 3.38Å; I9-I13 WeakPolarHBondContact O-CG1 3.33Å; I9-I13 PolarHBondContact O-N 2.95Å; L10-I13 PolarHBondContact O-N 3.09Å; I13-S15 VanDerWaalsContact C-N 3.34Å; I13-C16 PolarHBondContact O-N 3.48Å
14I57.9Low77.5Confident117 Ų11777 Ų7760%0.643%0.429SS*.Hα-helixtrans-67-36.2176.5-66.5164.2000111L10 T11 C16L10-I14 HydrophobicContact CD2-CD1 4.31Å; L10-I14 HydrophobicContact CG-CD1 4Å; L10-I14 WeakPolarHBondContact O-CB 3.17Å; L10-I14 WeakPolarHBondContact O-CD1 3.44Å; L10-I14 WeakPolarHBondContact O-CG1 3.16Å; L10-I14 PolarHBondContact O-N 2.96Å; T11-I14 PolarHBondContact O-N 3.13Å; I14-C16 VanDerWaalsContact C-N 3.31Å; I14-C16 PolarHBondContact O-N 3.04Å
15S54.8Low78.3Confident91 Ų9171 Ų7164%0.63640%0.398SS*.Hα-helixtrans-72.5-22.6177-550000113.1T11 S12 I13 V17T11-S15 WeakPolarHBondContact O-CB 3.25Å; T11-S15 PolarHBondContact O-N 3.47Å; T11-S15 PolarHBondContact O-OG 2.91Å; S12-S15 PolarHBondContact O-N 3.44Å; I13-S15 VanDerWaalsContact C-N 3.34Å; S15-V17 VanDerWaalsContact C-N 3.32Å
16C53.5Low79Confident111 Ų11166.4 Ų66.475%0.7537%0.374SS*.THydrogen-bonded Turntrans-79-10.7179.9-85.60000114S12 I13 I14S12-C16 WeakPolarHBondContact O-CB 3.25Å; S12-C16 PolarHBondContact O-N 3.45Å; S12-C16 PolarHBondContact O-SG 2.9Å; S12-C16 VanDerWaalsContact O-SG 3.37Å; I13-C16 PolarHBondContact O-N 3.48Å; I14-C16 VanDerWaalsContact C-N 3.31Å; I14-C16 PolarHBondContact O-N 3.04Å
17V60.2Low79.7Confident105 Ų10562 Ų6264%0.63635%0.35SS*.  trans-109.169.8174.4-168.40000108.9S15 S19S15-V17 VanDerWaalsContact C-N 3.32Å; V17-S19 VanDerWaalsContact C-N 3.3Å; V17-S19 PolarHBondContact O-N 2.85Å
18S64.8Low80.4Confident72 Ų7257 Ų5750%0.50333%0.325SS..  trans-75.787.5167.6-177.90000108.6Y20S18-Y20 PolarHBondContact O-N 3.34Å
19S89.1Confident81Confident55 Ų5551 Ų5139%0.38530%0.298SS..  trans-78.2100.6170.8163.30000109V17 G48 N50V17-S19 VanDerWaalsContact C-N 3.3Å; V17-S19 PolarHBondContact O-N 2.85Å; S19-G48 WeakPolarHBondContact CB-O 3.45Å; S19-G48 PolarHBondContact OG-O 3.32Å; S19-N50 PolarHBondContact OG-N 3.26Å
20Y97.6Very high81.4Confident36 Ų3647.9 Ų47.914%0.14129%0.286CS..  trans-66.4145.2170.8-64.2-75.2000110.5S18 N49 N50 D142 E467 A470 R471S18-Y20 PolarHBondContact O-N 3.34Å; Y20-N49 WeakPolarHBondContact CB-OD1 3.2Å; Y20-N49 PolarHBondContact N-OD1 2.9Å; Y20-N50 PolarHBondContact O-N 3.46Å; Y20-D142 WeakPolarHBondContact CA-OD2 3.47Å; Y20-D142 HydrophobicContact CD1-CB 4.12Å; Y20-E467 HydrophobicContact CD2-CB 4.17Å; Y20-E467 HydrophobicContact CD2-CG 3.9Å; Y20-E467 HydrophobicContact CE2-CB 3.86Å; Y20-E467 HydrophobicContact CE2-CG 4Å; Y20-A470 HydrophobicContact CD1-CB 3.55Å; Y20-A470 HydrophobicContact CD2-CB 4.15Å; Y20-A470 HydrophobicContact CE1-CB 3.99Å; Y20-A470 HydrophobicContact CG-CB 3.64Å; Y20-R471 HydrophobicContact CE1-CB 4.45Å; Y20-R471 WeakPolarHBondContact OH-CB 3.45Å
21K98Very high82.3Confident46 Ų4644.9 Ų44.920%0.227%0.269CS..EExtended strand (participates in β ladder)trans-95111.5175.5-160.4-178.2-172.4169.90109.6N50 E139 Y141 D142K21-N50 CarbonylContact C-O 3.55Å; K21-N50 WeakPolarHBondContact CA-O 3.42Å; K21-N50 HydrophobicContact CG-CB 4.45Å; K21-E139 WeakPolarHBondContact CD-O 3.42Å; K21-E139 WeakPolarHBondContact CE-O 2.99Å; K21-E139 WeakPolarHBondContact CE-OE2 3.09Å; K21-E139 PolarHBondContact NZ-O 3Å; K21-E139 IonicContact NZ-OE2 3.19Å; K21-E139 PolarHBondContact NZ-OE2 3.31Å; K21-Y141 HydrophobicContact CB-CD1 4.36Å; K21-Y141 HydrophobicContact CD-CD1 4.18Å; K21-Y141 HydrophobicContact CD-CE1 4.37Å; K21-Y141 HydrophobicContact CG-CD1 3.7Å; K21-Y141 HydrophobicContact CG-CE1 3.95Å; K21-D142 PolarHBondContact N-OD2 3.08Å; K21-D142 PolarHBondContact O-N 3.45Å
22I98.7Very high83.3Confident0 Ų044.6 Ų44.60%027%0.27CS..EExtended strand (participates in β ladder)trans-116.3128.6-169.7-58.6173.8000109.6L44 N49 N50 V51 T52 L143 I145 V466I22-L44 HydrophobicContact CD1-CD1 4.29Å; I22-N49 HydrophobicContact CD1-CB 3.86Å; I22-N50 PolarHBondContact N-O 2.84Å; I22-V51 HydrophobicContact CB-CG2 4.44Å; I22-V51 WeakPolarHBondContact O-CA 3.35Å; I22-T52 PolarHBondContact O-N 3.5Å; I22-L143 WeakPolarHBondContact CA-O 3.39Å; I22-I145 HydrophobicContact CG2-CD1 3.75Å; I22-I145 HydrophobicContact CG2-CG1 3.83Å; I22-V466 HydrophobicContact CD1-CG1 3.59Å
23L98.8Very high84.6Confident0 Ų043.5 Ų43.50%026%0.259CS..EExtended strand (participates in β ladder)trans-96.7119.9169.1176.862.2000109.5T52 L54 L136 Y141 L143 A144 I145 I160L23-T52 HydrophobicContact CD1-CG2 4.39Å; L23-L54 HydrophobicContact CD1-CB 4.3Å; L23-L136 HydrophobicContact CD1-CD2 4.02Å; L23-L136 HydrophobicContact CD2-CD2 4.3Å; L23-Y141 HydrophobicContact CB-CD1 3.69Å; L23-Y141 HydrophobicContact CB-CD2 3.81Å; L23-Y141 HydrophobicContact CB-CE1 3.88Å; L23-Y141 HydrophobicContact CB-CE2 3.97Å; L23-Y141 HydrophobicContact CB-CG 3.67Å; L23-Y141 HydrophobicContact CD1-CE2 4.19Å; L23-Y141 HydrophobicContact CD2-CD2 4.15Å; L23-Y141 HydrophobicContact CD2-CE2 4.12Å; L23-Y141 HydrophobicContact CG-CD2 4.47Å; L23-Y141 HydrophobicContact CG-CE2 4.32Å; L23-L143 PolarHBondContact N-O 3.38Å; L23-A144 HydrophobicContact CB-CB 4.2Å; L23-A144 CarbonylContact O-C 3.57Å; L23-A144 WeakPolarHBondContact O-CA 3.26Å; L23-I145 PolarHBondContact O-N 3.47Å; L23-I160 HydrophobicContact CD2-CD1 3.73Å
24L98.8Very high86.1Confident0 Ų038.6 Ų38.60%023%0.234CC..EExtended strand (participates in β ladder)trans-107.3119.4171.6-167.1149.8000109.7S26 L37 A41 V51 T52 V53 L54 I145L24-S26 VanDerWaalsContact CD2-CB 3.45Å; L24-L37 HydrophobicContact CD2-CB 4.3Å; L24-A41 HydrophobicContact CD1-CB 4.1Å; L24-V51 HydrophobicContact CB-CG1 4.45Å; L24-T52 PolarHBondContact N-O 3.39Å; L24-V53 HydrophobicContact CB-CG2 4.45Å; L24-V53 HydrophobicContact CD2-CG1 3.91Å; L24-V53 CarbonylContact O-C 3.52Å; L24-V53 VanDerWaalsContact O-CA 3.28Å; L24-V53 WeakPolarHBondContact O-CA 3.5Å; L24-L54 PolarHBondContact O-N 3.41Å; L24-I145 CarbonylContact C-O 3.38Å; L24-I145 WeakPolarHBondContact CA-O 3.45Å; L24-I145 HydrophobicContact CB-CB 4.36Å; L24-I145 HydrophobicContact CD1-CB 4.2Å; L24-I145 HydrophobicContact CD1-CD1 4.49Å; L24-I145 HydrophobicContact CD1-CG2 4.07Å; L24-I145 HydrophobicContact CG-CB 4.03Å; L24-I145 HydrophobicContact CG-CG2 4.19Å
25Y98.7Very high87.8Confident2 Ų236.2 Ų36.21%0.00822%0.219CC..EExtended strand (participates in β ladder)trans-90.2115.3170.5-174.2-82.9000108.8L54 P56 V126 I145 T146 D150 C152 L156Y25-L54 HydrophobicContact CD2-CD2 3.83Å; Y25-L54 HydrophobicContact CD2-CG 4.19Å; Y25-L54 HydrophobicContact CE2-CD2 4.07Å; Y25-L54 HydrophobicContact CE2-CG 4.47Å; Y25-P56 HydrophobicContact CE1-CG 4.28Å; Y25-P56 HydrophobicContact CE2-CG 3.79Å; Y25-P56 WeakPolarHBondContact OH-CG 3.31Å; Y25-V126 HydrophobicContact CE2-CG1 4.19Å; Y25-I145 PolarHBondContact N-O 2.99Å; Y25-T146 WeakPolarHBondContact CD1-OG1 3.46Å; Y25-D150 HydrophobicContact CE1-CB 4.31Å; Y25-D150 WeakPolarHBondContact CE1-OD2 3.39Å; Y25-C152 WeakPolarHBondContact OH-CB 3.41Å; Y25-L156 HydrophobicContact CD2-CD2 3.62Å; Y25-L156 HydrophobicContact CE2-CD2 4.07Å
26S97.7Very high89.8Confident3 Ų332.3 Ų32.32%0.02119%0.191CC..  trans-143.4103.7177.5174.20000108.9L24 L37 L54 M55L24-S26 VanDerWaalsContact CD2-CB 3.45Å; S26-L37 WeakPolarHBondContact OG-CD1 3.21Å; S26-L54 PolarHBondContact N-O 2.84Å; S26-M55 VanDerWaalsContact O-CA 3.29Å; S26-M55 WeakPolarHBondContact O-CA 3.25Å
27N96.4Very high91.9Very high7 Ų727.2 Ų27.24%0.03716%0.157CC..  trans-61.5165.8171.674.729.2000112.1F29 V34 P56 F58 D150N27-F29 VanDerWaalsContact OD1-CB 3.28Å; N27-F29 WeakPolarHBondContact OD1-CB 3.31Å; N27-F29 PolarHBondContact OD1-N 3.45Å; N27-V34 WeakPolarHBondContact O-CG2 3.34Å; N27-P56 CarbonylContact C-O 3.58Å; N27-P56 WeakPolarHBondContact CA-O 3.34Å; N27-P56 HydrophobicContact CB-CB 4.19Å; N27-P56 HydrophobicContact CB-CG 4.37Å; N27-F58 HydrophobicContact CB-CD2 3.75Å; N27-F58 HydrophobicContact CB-CE2 3.62Å; N27-D150 VanDerWaalsContact ND2-CB 3.33Å; N27-D150 WeakPolarHBondContact ND2-CB 3.39Å; N27-D150 PolarHBondContact ND2-OD2 3.29Å
28L95.5Very high93.7Very high0 Ų022.3 Ų22.30%013%0.127CC..SBendtrans-101.156.9171.5-59.7-179.5000110V34 M55 P56 V57 D59 L62 T66 F76L28-V34 HydrophobicContact CD2-CG1 4.02Å; L28-V34 HydrophobicContact CD2-CG2 4.13Å; L28-M55 HydrophobicContact CD2-CE 3.46Å; L28-M55 VanDerWaalsContact CD2-CE 3.46Å; L28-M55 HydrophobicContact CD2-SD 4.28Å; L28-M55 HydrophobicContact CG-CB 4.3Å; L28-M55 HydrophobicContact CG-CE 4.47Å; L28-P56 PolarHBondContact N-O 2.9Å; L28-V57 HydrophobicContact CD1-CG1 4.49Å; L28-V57 HydrophobicContact CD1-CG2 4.07Å; L28-D59 PolarHBondContact O-N 3.42Å; L28-D59 VanDerWaalsContact O-N 3.14Å; L28-L62 HydrophobicContact CB-CB 4.06Å; L28-T66 HydrophobicContact CD2-CG2 4.41Å; L28-F76 HydrophobicContact CD1-CD1 4.35Å; L28-F76 HydrophobicContact CD1-CE1 4.13Å
29F91.6Very high95.2Very high18 Ų1819.8 Ų19.88%0.07911%0.11CC..SBendtrans-114.2126.7169.6177.6-89000109.2N27 F58 M87 M90 F119 F149N27-F29 VanDerWaalsContact OD1-CB 3.28Å; N27-F29 WeakPolarHBondContact OD1-CB 3.31Å; N27-F29 PolarHBondContact OD1-N 3.45Å; F29-F58 HydrophobicContact CB-CB 4Å; F29-F58 HydrophobicContact CB-CD2 4.07Å; F29-F58 HydrophobicContact CB-CG 4Å; F29-F58 HydrophobicContact CD2-CB 4.28Å; F29-F58 HydrophobicContact CD2-CD1 4.29Å; F29-F58 HydrophobicContact CD2-CG 4.37Å; F29-M87 HydrophobicContact CD2-CE 3.72Å; F29-M87 HydrophobicContact CD2-SD 3.72Å; F29-M87 HydrophobicContact CE2-CE 3.72Å; F29-M87 HydrophobicContact CE2-SD 3.79Å; F29-M90 HydrophobicContact CE2-CE 4.26Å; F29-M90 HydrophobicContact CE2-CG 4.37Å; F29-M90 HydrophobicContact CZ-CE 4.34Å; F29-F119 HydrophobicContact CB-CZ 4.46Å; F29-F119 HydrophobicContact CD1-CE2 4.44Å; F29-F119 AromaticContact CD1-CZ 3.95Å; F29-F119 HydrophobicContact CD1-CZ 3.95Å; F29-F119 HydrophobicContact CD2-CE2 4.18Å; F29-F119 HydrophobicContact CD2-CZ 4.29Å; F29-F119 HydrophobicContact CE1-CE2 4.41Å; F29-F119 HydrophobicContact CE1-CZ 4.24Å; F29-F119 HydrophobicContact CE2-CE2 4.14Å; F29-F119 HydrophobicContact CG-CE2 4.32Å; F29-F119 AromaticContact CG-CZ 3.98Å; F29-F119 HydrophobicContact CG-CZ 3.98Å; F29-F119 HydrophobicContact CZ-CE2 4.26Å; F29-F149 AromaticContact CD1-CE1 3.7Å; F29-F149 HydrophobicContact CD1-CE1 3.7Å; F29-F149 HydrophobicContact CD1-CZ 4.44Å; F29-F149 AromaticContact CE1-CE1 3.53Å; F29-F149 HydrophobicContact CE1-CE1 3.53Å; F29-F149 AromaticContact CE1-CZ 3.85Å; F29-F149 HydrophobicContact CE1-CZ 3.85Å
30G88.9Confident95.7Very high14 Ų1417.1 Ų17.114%0.1449%0.092CC..  trans64.9104.8177.900000113.7S32 H33 V34G30-S32 PolarHBondContact O-N 2.97Å; G30-H33 PolarHBondContact O-N 3.14Å; G30-V34 PolarHBondContact O-N 3.11Å
31H89.1Confident95.7Very high44 Ų4415.4 Ų15.420%0.2049%0.085CC..Hα-helixtrans-54.8-27.7-176.3-174.6-114.6000114.5K35 L62 S67H31-K35 WeakPolarHBondContact O-CB 3.5Å; H31-K35 PolarHBondContact O-N 3.11Å; H31-L62 HydrophobicContact CB-CD2 4Å; H31-S67 PolarHBondContact NE2-OG 3.19Å
32S89.8Confident95.7Very high61 Ų6113.9 Ų13.943%0.4278%0.079SC..Hα-helixtrans-64.3-40.5174.748.30000113.4G30 V36G30-S32 PolarHBondContact O-N 2.97Å; S32-V36 PolarHBondContact O-N 3.17Å
33H93.6Very high95.7Very high28 Ų2814.7 Ų14.713%0.138%0.083CC..Hα-helixtrans-68.5-50.3177.8-66.9-108.6000109.8G30 K35 V36 L37 E147 F149 T170G30-H33 PolarHBondContact O-N 3.14Å; H33-K35 VanDerWaalsContact C-N 3.3Å; H33-K35 PolarHBondContact O-N 3.28Å; H33-V36 PolarHBondContact O-N 3.34Å; H33-V36 VanDerWaalsContact O-N 3.12Å; H33-L37 PolarHBondContact O-N 2.92Å; H33-L37 VanDerWaalsContact O-N 3.08Å; H33-E147 IonicContact CE1-OE1 2.58Å; H33-E147 IonicContact CE1-OE2 3.28Å; H33-E147 IonicContact CG-OE2 2.83Å; H33-E147 IonicContact ND1-OE1 3.45Å; H33-E147 PolarHBondContact ND1-OE1 3.41Å; H33-E147 IonicContact ND1-OE2 2.89Å; H33-E147 PolarHBondContact ND1-OE2 2.83Å; H33-F149 AromaticContact CE1-CD2 3.86Å; H33-F149 AromaticContact CE1-CG 3.91Å; H33-T170 HydrophobicContact CB-CG2 4.35Å; H33-T170 PolarHBondContact CE1-OG1 3.31Å; H33-T170 PolarHBondContact ND1-OG1 3.47Å
34V94.9Very high95.7Very high1 Ų114.7 Ų14.71%0.0068%0.083CC..Hα-helixtrans-53.8-44.7177-179.60000111.4N27 L28 G30 V36 A38 L62 T66N27-V34 WeakPolarHBondContact O-CG2 3.34Å; L28-V34 HydrophobicContact CD2-CG1 4.02Å; L28-V34 HydrophobicContact CD2-CG2 4.13Å; G30-V34 PolarHBondContact O-N 3.11Å; V34-V36 VanDerWaalsContact C-N 3.35Å; V34-V36 PolarHBondContact O-N 3.44Å; V34-A38 WeakPolarHBondContact O-CB 3.39Å; V34-A38 PolarHBondContact O-N 3.37Å; V34-L62 HydrophobicContact CG2-CD1 4.46Å; V34-T66 VanDerWaalsContact CG1-O 3.26Å; V34-T66 WeakPolarHBondContact CG1-O 3.16Å
35K94.2Very high95.7Very high67 Ų6716.4 Ų16.429%0.2919%0.094SC..Hα-helixtrans-61.1-39.6-179.5-173.8-174.1175.3-170.40112.7H31 H33 A39 E383H31-K35 WeakPolarHBondContact O-CB 3.5Å; H31-K35 PolarHBondContact O-N 3.11Å; H33-K35 VanDerWaalsContact C-N 3.3Å; H33-K35 PolarHBondContact O-N 3.28Å; K35-A39 WeakPolarHBondContact O-CB 3.46Å; K35-A39 PolarHBondContact O-N 3.46Å; K35-A39 VanDerWaalsContact O-N 3.14Å; K35-E383 IonicContact NZ-OE1 3.48Å; K35-E383 PolarHBondContact NZ-OE1 3.26Å
36V95.7Very high95.6Very high9 Ų921.9 Ų21.96%0.05512%0.123CC..Hα-helixtrans-75-46.3-178.6175.10000110.9S32 H33 V34 A39 A40 T170S32-V36 PolarHBondContact O-N 3.17Å; H33-V36 PolarHBondContact O-N 3.34Å; H33-V36 VanDerWaalsContact O-N 3.12Å; V34-V36 VanDerWaalsContact C-N 3.35Å; V34-V36 PolarHBondContact O-N 3.44Å; V36-A39 PolarHBondContact O-N 3.49Å; V36-A40 PolarHBondContact O-N 3.42Å; V36-T170 HydrophobicContact CB-CG2 3.68Å; V36-T170 HydrophobicContact CG1-CG2 3.83Å; V36-T170 HydrophobicContact CG2-CG2 4.43Å
37L97.6Very high95.6Very high4 Ų423.9 Ų23.92%0.02114%0.14CC..Hα-helixtrans-66.5-37.4178.2-69173.4000112.1L24 S26 H33 A40 A41 E147 I168 T170L24-L37 HydrophobicContact CD2-CB 4.3Å; S26-L37 WeakPolarHBondContact OG-CD1 3.21Å; H33-L37 PolarHBondContact O-N 2.92Å; H33-L37 VanDerWaalsContact O-N 3.08Å; L37-A40 PolarHBondContact O-N 2.91Å; L37-A41 PolarHBondContact O-N 2.91Å; L37-E147 HydrophobicContact CD1-CB 3.99Å; L37-E147 HydrophobicContact CD2-CB 4.4Å; L37-I168 HydrophobicContact CD2-CB 3.91Å; L37-I168 HydrophobicContact CD2-CD1 4.45Å; L37-I168 HydrophobicContact CD2-CG2 3.93Å; L37-T170 HydrophobicContact CD2-CG2 4.49Å; L37-T170 HydrophobicContact CG-CG2 4.04Å
38A97.6Very high95.6Very high2 Ų225.4 Ų25.42%0.01716%0.157CC..Hα-helixtrans-63.9-40.6172.900000112.4V34 A40 A41 D42 T66 L68V34-A38 WeakPolarHBondContact O-CB 3.39Å; V34-A38 PolarHBondContact O-N 3.37Å; A38-A40 VanDerWaalsContact C-N 3.32Å; A38-A40 PolarHBondContact O-N 2.92Å; A38-A41 PolarHBondContact O-N 3.27Å; A38-D42 WeakPolarHBondContact O-CB 3.31Å; A38-D42 PolarHBondContact O-N 3.24Å; A38-T66 WeakPolarHBondContact CB-O 3.47Å; A38-L68 HydrophobicContact CB-CD2 3.66Å; A38-L68 HydrophobicContact CB-CG 4.03Å
39A97.4Very high95.7Very high18 Ų1825.7 Ų25.715%0.14916%0.159CC..Hα-helixtrans-62.4-40.7174.100000111.5K35 V36 D42 I43 L275K35-A39 WeakPolarHBondContact O-CB 3.46Å; K35-A39 PolarHBondContact O-N 3.46Å; K35-A39 VanDerWaalsContact O-N 3.14Å; V36-A39 PolarHBondContact O-N 3.49Å; A39-D42 PolarHBondContact O-N 2.9Å; A39-I43 WeakPolarHBondContact O-CB 3.26Å; A39-I43 VanDerWaalsContact O-CD1 3.29Å; A39-I43 WeakPolarHBondContact O-CD1 3.43Å; A39-I43 WeakPolarHBondContact O-CG1 3.39Å; A39-I43 PolarHBondContact O-N 2.97Å; A39-L275 HydrophobicContact CB-CB 4.41Å
40A98.5Very high96Very high0 Ų028.3 Ų28.30%017%0.173CC..Hα-helixtrans-63.4-44.6175.200000112V36 L37 A38 I43 L44 I168 L275 L462V36-A40 PolarHBondContact O-N 3.42Å; L37-A40 PolarHBondContact O-N 2.91Å; A38-A40 VanDerWaalsContact C-N 3.32Å; A38-A40 PolarHBondContact O-N 2.92Å; A40-I43 PolarHBondContact O-N 3.49Å; A40-L44 VanDerWaalsContact O-CG 3.29Å; A40-L44 WeakPolarHBondContact O-CG 3.47Å; A40-L44 PolarHBondContact O-N 2.93Å; A40-L44 VanDerWaalsContact O-N 3.07Å; A40-I168 HydrophobicContact CB-CD1 3.67Å; A40-L275 HydrophobicContact CB-CD1 4.37Å; A40-L462 HydrophobicContact CB-CD2 3.8Å
41A98.6Very high96.5Very high0 Ų027.9 Ų27.90%017%0.168CC..Hα-helixtrans-58.4-48.7175.600000111.8L24 L37 A38 L44 T45 V51 V53 L68 T71L24-A41 HydrophobicContact CD1-CB 4.1Å; L37-A41 PolarHBondContact O-N 2.91Å; A38-A41 PolarHBondContact O-N 3.27Å; A41-L44 PolarHBondContact O-N 3.43Å; A41-T45 WeakPolarHBondContact O-CB 3.5Å; A41-T45 PolarHBondContact O-N 3.06Å; A41-T45 PolarHBondContact O-OG1 3.38Å; A41-T45 VanDerWaalsContact O-OG1 3.05Å; A41-V51 HydrophobicContact CB-CG1 4.23Å; A41-V53 HydrophobicContact CB-CG2 3.94Å; A41-L68 HydrophobicContact CB-CD2 3.72Å; A41-T71 HydrophobicContact CB-CG2 4.41Å; A41-T71 PolarHBondContact O-OG1 3.43Å; A41-T71 VanDerWaalsContact O-OG1 3.14Å
42D98.5Very high97Very high13 Ų1325.8 Ų25.87%0.0716%0.158CC..Hα-helixtrans-63.9-42179.8-76.2-17.8000112A38 A39 L44 T45 D46 K69 S70 T71A38-D42 WeakPolarHBondContact O-CB 3.31Å; A38-D42 PolarHBondContact O-N 3.24Å; A39-D42 PolarHBondContact O-N 2.9Å; D42-L44 VanDerWaalsContact C-N 3.32Å; D42-L44 PolarHBondContact O-N 3.28Å; D42-T45 PolarHBondContact O-N 3.39Å; D42-D46 VanDerWaalsContact O-CB 3.29Å; D42-D46 WeakPolarHBondContact O-CB 3.07Å; D42-D46 PolarHBondContact O-N 3.49Å; D42-K69 VanDerWaalsContact CG-N 3.34Å; D42-K69 PolarHBondContact OD1-N 3.16Å; D42-K69 VanDerWaalsContact OD1-N 3.14Å; D42-K69 WeakPolarHBondContact OD2-CB 3.35Å; D42-K69 PolarHBondContact OD2-N 3.07Å; D42-S70 WeakPolarHBondContact CA-OG 3.26Å; D42-S70 WeakPolarHBondContact CB-OG 3.43Å; D42-S70 PolarHBondContact O-OG 2.91Å; D42-S70 PolarHBondContact OD1-N 3.44Å; D42-S70 PolarHBondContact OD1-OG 3.18Å; D42-T71 WeakPolarHBondContact CA-OG1 3.41Å; D42-T71 PolarHBondContact N-OG1 3.09Å; D42-T71 WeakPolarHBondContact OD1-CB 3.39Å; D42-T71 PolarHBondContact OD1-N 3.45Å; D42-T71 PolarHBondContact OD1-OG1 3.48Å
43I98.1Very high97.4Very high17 Ų1722.9 Ų22.99%0.08714%0.138CC..Hα-helixtrans-61-42.3176.6-71.7161.6000111.2A39 A40 A47 L275 K459 L462 I463A39-I43 WeakPolarHBondContact O-CB 3.26Å; A39-I43 VanDerWaalsContact O-CD1 3.29Å; A39-I43 WeakPolarHBondContact O-CD1 3.43Å; A39-I43 WeakPolarHBondContact O-CG1 3.39Å; A39-I43 PolarHBondContact O-N 2.97Å; A40-I43 PolarHBondContact O-N 3.49Å; I43-A47 WeakPolarHBondContact O-CB 3.32Å; I43-A47 PolarHBondContact O-N 2.9Å; I43-A47 VanDerWaalsContact O-N 3.07Å; I43-L275 HydrophobicContact CD1-CB 4.07Å; I43-L275 HydrophobicContact CD1-CD1 4.14Å; I43-L275 HydrophobicContact CD1-CD2 3.91Å; I43-L275 HydrophobicContact CD1-CG 4.26Å; I43-K459 HydrophobicContact CD1-CB 4.28Å; I43-K459 HydrophobicContact CD1-CD 4.09Å; I43-K459 HydrophobicContact CD1-CG 3.77Å; I43-K459 HydrophobicContact CG1-CD 4.23Å; I43-K459 HydrophobicContact CG1-CG 4.33Å; I43-K459 HydrophobicContact CG2-CB 4.14Å; I43-L462 HydrophobicContact CB-CD2 4.09Å; I43-L462 HydrophobicContact CD1-CD2 4.3Å; I43-L462 HydrophobicContact CG2-CD2 3.93Å; I43-I463 HydrophobicContact CG2-CD1 3.83Å; I43-I463 HydrophobicContact CG2-CG1 3.77Å
44L98.6Very high97.6Very high0 Ų021.6 Ų21.60%013%0.132CC..Hα-helixtrans-69.1-40.8178.6-68.6170.4000111.8I22 A40 A41 D42 A47 G48 N49 V51 I145 L462 I463 V466I22-L44 HydrophobicContact CD1-CD1 4.29Å; A40-L44 VanDerWaalsContact O-CG 3.29Å; A40-L44 WeakPolarHBondContact O-CG 3.47Å; A40-L44 PolarHBondContact O-N 2.93Å; A40-L44 VanDerWaalsContact O-N 3.07Å; A41-L44 PolarHBondContact O-N 3.43Å; D42-L44 VanDerWaalsContact C-N 3.32Å; D42-L44 PolarHBondContact O-N 3.28Å; L44-A47 PolarHBondContact O-N 3.44Å; L44-G48 PolarHBondContact O-N 2.91Å; L44-N49 VanDerWaalsContact O-CB 3.31Å; L44-N49 WeakPolarHBondContact O-CB 3.42Å; L44-N49 PolarHBondContact O-N 3.32Å; L44-N49 VanDerWaalsContact O-N 3.09Å; L44-N49 PolarHBondContact O-ND2 2.98Å; L44-V51 HydrophobicContact CB-CG2 3.75Å; L44-I145 HydrophobicContact CD1-CD1 3.58Å; L44-L462 HydrophobicContact CD2-CG 4.34Å; L44-L462 HydrophobicContact CG-CD2 4.41Å; L44-I463 HydrophobicContact CD2-CG1 4.44Å; L44-V466 HydrophobicContact CD1-CG1 4.04Å; L44-V466 HydrophobicContact CD1-CG2 4.37Å; L44-V466 HydrophobicContact CD2-CB 3.84Å; L44-V466 HydrophobicContact CD2-CG1 3.63Å; L44-V466 HydrophobicContact CD2-CG2 4.16Å
45T98.4Very high97.8Very high36 Ų3621.6 Ų21.622%0.22113%0.132CC..Hα-helixtrans-61.2-46.7173.5-63.70000111.3A41 D42 A47 G48 V51 T71A41-T45 WeakPolarHBondContact O-CB 3.5Å; A41-T45 PolarHBondContact O-N 3.06Å; A41-T45 PolarHBondContact O-OG1 3.38Å; A41-T45 VanDerWaalsContact O-OG1 3.05Å; D42-T45 PolarHBondContact O-N 3.39Å; T45-A47 PolarHBondContact O-N 3.37Å; T45-G48 WeakPolarHBondContact O-CA 3.27Å; T45-G48 PolarHBondContact O-N 2.86Å; T45-V51 WeakPolarHBondContact OG1-CB 3.25Å; T45-V51 WeakPolarHBondContact OG1-CG2 3.36Å; T45-T71 PolarHBondContact OG1-OG1 2.87Å
46D97.4Very high98Very high117 Ų11718.4 Ų18.463%0.62612%0.118SC*.Hα-helixtrans-65.5-26.4179.6-69-10000112.1D42 G48 S70D42-D46 VanDerWaalsContact O-CB 3.29Å; D42-D46 WeakPolarHBondContact O-CB 3.07Å; D42-D46 PolarHBondContact O-N 3.49Å; D46-G48 PolarHBondContact O-N 3.24Å; D46-S70 WeakPolarHBondContact OD1-CB 3.46Å; D46-S70 PolarHBondContact OD1-OG 3.35Å
47A97.2Very high98Very high45 Ų4518 Ų1837%0.37212%0.116SC..THydrogen-bonded Turntrans-76.8-417200000113.7I43 L44 T45 I463I43-A47 WeakPolarHBondContact O-CB 3.32Å; I43-A47 PolarHBondContact O-N 2.9Å; I43-A47 VanDerWaalsContact O-N 3.07Å; L44-A47 PolarHBondContact O-N 3.44Å; T45-A47 PolarHBondContact O-N 3.37Å; A47-I463 HydrophobicContact CB-CD1 3.68Å; A47-I463 HydrophobicContact CB-CG1 3.87Å; A47-I463 HydrophobicContact CB-CG2 4.02Å
48G97Very high97.8Very high39 Ų3917.8 Ų17.840%0.40212%0.115SC..THydrogen-bonded Turntrans96.69.5177.300000115S19 L44 T45 D46S19-G48 WeakPolarHBondContact CB-O 3.45Å; S19-G48 PolarHBondContact OG-O 3.32Å; L44-G48 PolarHBondContact O-N 2.91Å; T45-G48 WeakPolarHBondContact O-CA 3.27Å; T45-G48 PolarHBondContact O-N 2.86Å; D46-G48 PolarHBondContact O-N 3.24Å
49N98Very high97.5Very high7 Ų718.8 Ų18.84%0.03712%0.12CC..  trans-79.3148.7174-63.3-81.8000111.1Y20 I22 L44 V51 E467Y20-N49 WeakPolarHBondContact CB-OD1 3.2Å; Y20-N49 PolarHBondContact N-OD1 2.9Å; I22-N49 HydrophobicContact CD1-CB 3.86Å; L44-N49 VanDerWaalsContact O-CB 3.31Å; L44-N49 WeakPolarHBondContact O-CB 3.42Å; L44-N49 PolarHBondContact O-N 3.32Å; L44-N49 VanDerWaalsContact O-N 3.09Å; L44-N49 PolarHBondContact O-ND2 2.98Å; N49-V51 HydrophobicContact CB-CG2 4.22Å; N49-V51 PolarHBondContact O-N 3.37Å; N49-E467 PolarHBondContact ND2-OE1 2.92Å
50N97.8Very high97.1Very high72 Ų7221.5 Ų21.539%0.38513%0.132SC..EExtended strand (participates in β ladder)trans-87.994.1174.2-177.4-1.5000109.3S19 Y20 K21 I22S19-N50 PolarHBondContact OG-N 3.26Å; Y20-N50 PolarHBondContact O-N 3.46Å; K21-N50 CarbonylContact C-O 3.55Å; K21-N50 WeakPolarHBondContact CA-O 3.42Å; K21-N50 HydrophobicContact CG-CB 4.45Å; I22-N50 PolarHBondContact N-O 2.84Å
51V98.6Very high96.6Very high5 Ų526.2 Ų26.23%0.0316%0.157CC..EExtended strand (participates in β ladder)trans-97.5124-176.1-174.20000110.9I22 L24 A41 L44 T45 N49 V53 T71I22-V51 HydrophobicContact CB-CG2 4.44Å; I22-V51 WeakPolarHBondContact O-CA 3.35Å; L24-V51 HydrophobicContact CB-CG1 4.45Å; A41-V51 HydrophobicContact CB-CG1 4.23Å; L44-V51 HydrophobicContact CB-CG2 3.75Å; T45-V51 WeakPolarHBondContact OG1-CB 3.25Å; T45-V51 WeakPolarHBondContact OG1-CG2 3.36Å; N49-V51 HydrophobicContact CB-CG2 4.22Å; N49-V51 PolarHBondContact O-N 3.37Å; V51-V53 HydrophobicContact CG1-CG2 4.17Å; V51-T71 HydrophobicContact CB-CG2 4.01Å; V51-T71 HydrophobicContact CG1-CG2 4.02Å
52T98.7Very high96.1Very high0 Ų026.9 Ų26.90%016%0.161CC..EExtended strand (participates in β ladder)trans-103.4131165.2-53.20000109.2I22 L23 L24 N73 I75 Y141I22-T52 PolarHBondContact O-N 3.5Å; L23-T52 HydrophobicContact CD1-CG2 4.39Å; L24-T52 PolarHBondContact N-O 3.39Å; T52-N73 CarbonylContact C-O 3.4Å; T52-N73 WeakPolarHBondContact CA-O 3.49Å; T52-N73 PolarHBondContact OG1-ND2 2.83Å; T52-I75 HydrophobicContact CG2-CD1 3.79Å; T52-I75 HydrophobicContact CG2-CG1 4.11Å; T52-Y141 VanDerWaalsContact CB-OH 3.23Å; T52-Y141 WeakPolarHBondContact CB-OH 3.43Å; T52-Y141 WeakPolarHBondContact CG2-OH 3.36Å; T52-Y141 WeakPolarHBondContact OG1-CE1 3.37Å; T52-Y141 PolarHBondContact OG1-OH 3.09Å
53V98.8Very high95.8Very high1 Ų129.3 Ų29.31%0.00617%0.169CC..EExtended strand (participates in β ladder)trans-108.8117.7174.9-167.50000110.3L24 A41 V51 M55 L68 T71 N73 T74 I75L24-V53 HydrophobicContact CB-CG2 4.45Å; L24-V53 HydrophobicContact CD2-CG1 3.91Å; L24-V53 CarbonylContact O-C 3.52Å; L24-V53 VanDerWaalsContact O-CA 3.28Å; L24-V53 WeakPolarHBondContact O-CA 3.5Å; A41-V53 HydrophobicContact CB-CG2 3.94Å; V51-V53 HydrophobicContact CG1-CG2 4.17Å; V53-M55 HydrophobicContact CB-CG 4.3Å; V53-M55 HydrophobicContact CG1-CE 4.23Å; V53-M55 HydrophobicContact CG1-CG 3.6Å; V53-M55 HydrophobicContact CG1-SD 4.16Å; V53-L68 HydrophobicContact CB-CD1 4.36Å; V53-L68 HydrophobicContact CG2-CD1 4.22Å; V53-L68 HydrophobicContact CG2-CD2 4.25Å; V53-T71 HydrophobicContact CG2-CG2 3.72Å; V53-N73 PolarHBondContact N-O 3.13Å; V53-T74 HydrophobicContact CB-CG2 4.49Å; V53-T74 CarbonylContact O-C 3.59Å; V53-T74 VanDerWaalsContact O-CA 3.32Å; V53-T74 WeakPolarHBondContact O-CA 3.38Å; V53-I75 PolarHBondContact O-N 2.81Å
54L98.7Very high95.5Very high0 Ų035.6 Ų35.60%020%0.203CC..EExtended strand (participates in β ladder)trans-89.6121.6169.2175.159.9000109.2L23 L24 Y25 S26 P56 I75 V77 V126 L132 L136 L156L23-L54 HydrophobicContact CD1-CB 4.3Å; L24-L54 PolarHBondContact O-N 3.41Å; Y25-L54 HydrophobicContact CD2-CD2 3.83Å; Y25-L54 HydrophobicContact CD2-CG 4.19Å; Y25-L54 HydrophobicContact CE2-CD2 4.07Å; Y25-L54 HydrophobicContact CE2-CG 4.47Å; S26-L54 PolarHBondContact N-O 2.84Å; L54-P56 WeakPolarHBondContact O-CD 3.36Å; L54-I75 CarbonylContact C-O 3.54Å; L54-I75 WeakPolarHBondContact CA-O 3.28Å; L54-I75 HydrophobicContact CD1-CB 3.9Å; L54-I75 HydrophobicContact CD1-CG2 3.68Å; L54-V77 HydrophobicContact CD1-CG2 3.84Å; L54-V126 HydrophobicContact CD2-CG1 4.46Å; L54-L132 HydrophobicContact CD1-CD1 4.31Å; L54-L132 HydrophobicContact CD1-CD2 4.26Å; L54-L132 HydrophobicContact CD2-CD2 4.3Å; L54-L136 HydrophobicContact CD2-CD1 4.02Å; L54-L156 HydrophobicContact CD2-CD2 3.47Å; L54-L156 VanDerWaalsContact CD2-CD2 3.47Å
55M98.3Very high95.1Very high1 Ų141.7 Ų41.71%0.00523%0.229CC..EExtended strand (participates in β ladder)trans-123.585.1-171.4-55.5-167.410100112.3S26 L28 V53 V57 T66 L68 T74 I75 F76 V77S26-M55 VanDerWaalsContact O-CA 3.29Å; S26-M55 WeakPolarHBondContact O-CA 3.25Å; L28-M55 HydrophobicContact CD2-CE 3.46Å; L28-M55 VanDerWaalsContact CD2-CE 3.46Å; L28-M55 HydrophobicContact CD2-SD 4.28Å; L28-M55 HydrophobicContact CG-CB 4.3Å; L28-M55 HydrophobicContact CG-CE 4.47Å; V53-M55 HydrophobicContact CB-CG 4.3Å; V53-M55 HydrophobicContact CG1-CE 4.23Å; V53-M55 HydrophobicContact CG1-CG 3.6Å; V53-M55 HydrophobicContact CG1-SD 4.16Å; M55-V57 PolarHBondContact O-N 3.4Å; M55-T66 HydrophobicContact CE-CG2 4.08Å; M55-T66 HydrophobicContact SD-CG2 3.71Å; M55-L68 HydrophobicContact CE-CD1 4.13Å; M55-L68 HydrophobicContact SD-CD1 3.83Å; M55-T74 HydrophobicContact SD-CG2 4.38Å; M55-I75 PolarHBondContact N-O 3.29Å; M55-F76 HydrophobicContact CB-CD1 3.82Å; M55-F76 HydrophobicContact CB-CE1 3.94Å; M55-F76 HydrophobicContact CG-CE1 4.43Å; M55-F76 WeakPolarHBondContact O-CA 3.43Å; M55-F76 HydrophobicContact SD-CE1 3.88Å; M55-F76 HydrophobicContact SD-CZ 4.21Å; M55-V77 PolarHBondContact O-N 3.34Å
56P98.1Very high94.9Very high0 Ų041.2 Ų41.20%023%0.226CC..EExtended strand (participates in β ladder)trans-59.1127.5166.3-21.430.6000111.3Y25 N27 L28 L54 F58 V77 Q122 V126Y25-P56 HydrophobicContact CE1-CG 4.28Å; Y25-P56 HydrophobicContact CE2-CG 3.79Å; Y25-P56 WeakPolarHBondContact OH-CG 3.31Å; N27-P56 CarbonylContact C-O 3.58Å; N27-P56 WeakPolarHBondContact CA-O 3.34Å; N27-P56 HydrophobicContact CB-CB 4.19Å; N27-P56 HydrophobicContact CB-CG 4.37Å; L28-P56 PolarHBondContact N-O 2.9Å; L54-P56 WeakPolarHBondContact O-CD 3.36Å; P56-F58 PolarHBondContact O-N 3.37Å; P56-V77 CarbonylContact C-O 3.53Å; P56-V77 WeakPolarHBondContact CA-O 3.33Å; P56-Q122 HydrophobicContact CB-CG 4.07Å; P56-V126 HydrophobicContact CB-CG2 3.62Å; P56-V126 HydrophobicContact CG-CG2 3.55Å
57V96.6Very high94.7Very high0 Ų037.5 Ų37.50%021%0.209CC..  trans-90.2107.1-176.2-1740000109L28 M55 R63 F76 V77 A79L28-V57 HydrophobicContact CD1-CG1 4.49Å; L28-V57 HydrophobicContact CD1-CG2 4.07Å; M55-V57 PolarHBondContact O-N 3.4Å; V57-R63 HydrophobicContact CG1-CB 4.45Å; V57-R63 VanDerWaalsContact CG2-CD 3.5Å; V57-F76 HydrophobicContact CG2-CD1 4.2Å; V57-V77 WeakPolarHBondContact CG2-O 3.38Å; V57-V77 PolarHBondContact N-O 2.88Å; V57-A79 VanDerWaalsContact O-CA 3.22Å; V57-A79 WeakPolarHBondContact O-CA 3.48Å; V57-A79 WeakPolarHBondContact O-CB 3.24Å; V57-A79 PolarHBondContact O-N 2.92Å
58F93.7Very high94.7Very high0 Ų036.5 Ų36.50%020%0.197CC..SBendtrans-89.6-55.6168.7-79.4-103.1000110.5N27 F29 P56 V83 M87 F119 Q122N27-F58 HydrophobicContact CB-CD2 3.75Å; N27-F58 HydrophobicContact CB-CE2 3.62Å; F29-F58 HydrophobicContact CB-CB 4Å; F29-F58 HydrophobicContact CB-CD2 4.07Å; F29-F58 HydrophobicContact CB-CG 4Å; F29-F58 HydrophobicContact CD2-CB 4.28Å; F29-F58 HydrophobicContact CD2-CD1 4.29Å; F29-F58 HydrophobicContact CD2-CG 4.37Å; P56-F58 PolarHBondContact O-N 3.37Å; F58-V83 HydrophobicContact CB-CG1 4.44Å; F58-V83 HydrophobicContact CD1-CG1 4.04Å; F58-V83 HydrophobicContact CG-CG1 4.46Å; F58-M87 HydrophobicContact CB-CG 4.44Å; F58-M87 HydrophobicContact CB-SD 4.17Å; F58-M87 HydrophobicContact CD1-SD 4.37Å; F58-M87 WeakPolarHBondContact O-CG 3.48Å; F58-F119 HydrophobicContact CE1-CD1 4.39Å; F58-F119 AromaticContact CE1-CD2 3.89Å; F58-F119 HydrophobicContact CE1-CD2 3.89Å; F58-F119 HydrophobicContact CE1-CE2 4.06Å; F58-F119 HydrophobicContact CE1-CG 4.06Å; F58-F119 HydrophobicContact CE1-CZ 4.36Å; F58-F119 AromaticContact CZ-CD1 3.9Å; F58-F119 HydrophobicContact CZ-CD1 3.9Å; F58-F119 HydrophobicContact CZ-CD2 4.23Å; F58-F119 HydrophobicContact CZ-CE1 4.06Å; F58-F119 HydrophobicContact CZ-CE2 4.38Å; F58-F119 AromaticContact CZ-CG 3.98Å; F58-F119 HydrophobicContact CZ-CG 3.98Å; F58-F119 HydrophobicContact CZ-CZ 4.27Å; F58-Q122 HydrophobicContact CD1-CB 4.27Å; F58-Q122 HydrophobicContact CD1-CG 4.43Å; F58-Q122 HydrophobicContact CD2-CB 4.48Å; F58-Q122 HydrophobicContact CD2-CG 3.86Å; F58-Q122 HydrophobicContact CE1-CB 3.62Å; F58-Q122 HydrophobicContact CE1-CG 4.07Å; F58-Q122 HydrophobicContact CE2-CB 3.89Å; F58-Q122 HydrophobicContact CE2-CG 3.46Å; F58-Q122 VanDerWaalsContact CE2-CG 3.46Å; F58-Q122 HydrophobicContact CG-CG 4.35Å; F58-Q122 HydrophobicContact CZ-CB 3.42Å; F58-Q122 VanDerWaalsContact CZ-CB 3.42Å; F58-Q122 HydrophobicContact CZ-CG 3.59Å
59D90Very high94.7Very high24 Ų2441.4 Ų41.413%0.12821%0.208CC..  trans-101.7113.2179-172.2-8.3000110.7L28 N61 L62 M87L28-D59 PolarHBondContact O-N 3.42Å; L28-D59 VanDerWaalsContact O-N 3.14Å; D59-N61 PolarHBondContact O-N 2.98Å; D59-N61 VanDerWaalsContact O-N 3.12Å; D59-N61 WeakPolarHBondContact OD1-CB 3.31Å; D59-N61 PolarHBondContact OD1-N 2.83Å; D59-N61 PolarHBondContact OD1-ND2 3.44Å; D59-L62 HydrophobicContact CB-CB 4.49Å; D59-L62 HydrophobicContact CB-CD1 4.19Å; D59-L62 HydrophobicContact CB-CG 4.09Å; D59-L62 WeakPolarHBondContact O-CB 3.48Å; D59-L62 PolarHBondContact O-N 2.9Å; D59-M87 HydrophobicContact CB-CE 4.28Å
60N89.5Confident94.6Very high74 Ų7442.8 Ų42.840%0.39622%0.218SC..G310 helixtrans-57.9-25.9176.5-76.9-54.8000113L62 R63 E84N60-L62 PolarHBondContact O-N 2.97Å; N60-R63 VanDerWaalsContact O-CB 3.26Å; N60-R63 WeakPolarHBondContact O-CB 3.45Å; N60-R63 PolarHBondContact O-N 3.17Å; N60-E84 PolarHBondContact ND2-OE2 2.72Å
61N87.2Confident94.7Very high100 Ų10039.5 Ų39.554%0.53520%0.201SC..G310 helixtrans-66.5-19.7175.5-60.4-61.7000113D59D59-N61 PolarHBondContact O-N 2.98Å; D59-N61 VanDerWaalsContact O-N 3.12Å; D59-N61 WeakPolarHBondContact OD1-CB 3.31Å; D59-N61 PolarHBondContact OD1-N 2.83Å; D59-N61 PolarHBondContact OD1-ND2 3.44Å
62L89.9Confident94.6Very high14 Ų1446.9 Ų46.97%0.07323%0.232CC..G310 helixtrans-95.7-8.7178.1-60.1-175.5000113.1L28 H31 V34 D59 N60 N64 K65L28-L62 HydrophobicContact CB-CB 4.06Å; H31-L62 HydrophobicContact CB-CD2 4Å; V34-L62 HydrophobicContact CG2-CD1 4.46Å; D59-L62 HydrophobicContact CB-CB 4.49Å; D59-L62 HydrophobicContact CB-CD1 4.19Å; D59-L62 HydrophobicContact CB-CG 4.09Å; D59-L62 WeakPolarHBondContact O-CB 3.48Å; D59-L62 PolarHBondContact O-N 2.9Å; N60-L62 PolarHBondContact O-N 2.97Å; L62-N64 PolarHBondContact O-N 3.03Å; L62-N64 VanDerWaalsContact O-N 3.09Å; L62-K65 HydrophobicContact CD2-CB 4.45Å; L62-K65 CarbonylContact O-C 3.52Å; L62-K65 WeakPolarHBondContact O-CA 3.48Å; L62-K65 PolarHBondContact O-N 3.4Å
63R92Very high94.6Very high63 Ų6350.4 Ų50.424%0.23825%0.251CS..THydrogen-bonded Turntrans-53.5-35.1-177.5-175.760.617876.2-1.5114.1V57 N60 F76 E78V57-R63 HydrophobicContact CG1-CB 4.45Å; V57-R63 VanDerWaalsContact CG2-CD 3.5Å; N60-R63 VanDerWaalsContact O-CB 3.26Å; N60-R63 WeakPolarHBondContact O-CB 3.45Å; N60-R63 PolarHBondContact O-N 3.17Å; R63-F76 VanDerWaalsContact CZ-CD1 3.45Å; R63-F76 VanDerWaalsContact NH1-CZ 3.3Å; R63-F76 VanDerWaalsContact NH2-CD2 3.35Å; R63-F76 VanDerWaalsContact NH2-CG 3.29Å; R63-E78 IonicContact CZ-OE1 3.63Å; R63-E78 IonicContact NE-OE1 3.21Å; R63-E78 PolarHBondContact NE-OE1 3.43Å; R63-E78 IonicContact NE-OE2 3.86Å; R63-E78 IonicContact NH2-OE1 3.73Å; R63-E78 PolarHBondContact NH2-OE1 3.26Å
64N91.6Very high94.5Very high150 Ų15052.7 Ų52.780%0.80227%0.265SS*.THydrogen-bonded Turntrans-105.38.6177.8-64.7-34.4000113.2L62L62-N64 PolarHBondContact O-N 3.03Å; L62-N64 VanDerWaalsContact O-N 3.09Å
65K90.1Very high94.5Very high128 Ų12853.8 Ų53.856%0.55727%0.271SS*.  trans-125.950-177.9-61.4-179.7-178.71740111L62 S67L62-K65 HydrophobicContact CD2-CB 4.45Å; L62-K65 CarbonylContact O-C 3.52Å; L62-K65 WeakPolarHBondContact O-CA 3.48Å; L62-K65 PolarHBondContact O-N 3.4Å; K65-S67 PolarHBondContact O-N 3.22Å; K65-S67 VanDerWaalsContact O-N 3.16Å
66T94.1Very high94.5Very high25 Ų2556.2 Ų56.215%0.15328%0.281CS..  trans-67.6-12.2-178.162.40000114.1L28 V34 A38 M55 L68 F76L28-T66 HydrophobicContact CD2-CG2 4.41Å; V34-T66 VanDerWaalsContact CG1-O 3.26Å; V34-T66 WeakPolarHBondContact CG1-O 3.16Å; A38-T66 WeakPolarHBondContact CB-O 3.47Å; M55-T66 HydrophobicContact CE-CG2 4.08Å; M55-T66 HydrophobicContact SD-CG2 3.71Å; T66-L68 PolarHBondContact O-N 3.15Å; T66-L68 PolarHBondContact OG1-N 2.91Å; T66-F76 HydrophobicContact CG2-CE1 3.91Å; T66-F76 HydrophobicContact CG2-CZ 3.88Å
67S93.9Very high94.5Very high39 Ų3956.3 Ų56.327%0.27328%0.282SS..  trans61.7-4.7-172.4-64.50000116.2H31 K65H31-S67 PolarHBondContact NE2-OG 3.19Å; K65-S67 PolarHBondContact O-N 3.22Å; K65-S67 VanDerWaalsContact O-N 3.16Å
68L97Very high94.5Very high24 Ų2460.2 Ų60.213%0.12630%0.3CS..  trans-68.9138.6175.8-62.8168.7000110.9A38 A41 V53 M55 T66 T74A38-L68 HydrophobicContact CB-CD2 3.66Å; A38-L68 HydrophobicContact CB-CG 4.03Å; A41-L68 HydrophobicContact CB-CD2 3.72Å; V53-L68 HydrophobicContact CB-CD1 4.36Å; V53-L68 HydrophobicContact CG2-CD1 4.22Å; V53-L68 HydrophobicContact CG2-CD2 4.25Å; M55-L68 HydrophobicContact CE-CD1 4.13Å; M55-L68 HydrophobicContact SD-CD1 3.83Å; T66-L68 PolarHBondContact O-N 3.15Å; T66-L68 PolarHBondContact OG1-N 2.91Å; L68-T74 HydrophobicContact CD1-CG2 3.49Å; L68-T74 VanDerWaalsContact CD1-CG2 3.49Å
69K95.9Very high94.6Very high142 Ų14261.6 Ų61.662%0.61731%0.312SS*.SBendtrans-120.5-55.8-178.8-63174.6-174.2164.50111.9D42 K72D42-K69 VanDerWaalsContact CG-N 3.34Å; D42-K69 PolarHBondContact OD1-N 3.16Å; D42-K69 VanDerWaalsContact OD1-N 3.14Å; D42-K69 WeakPolarHBondContact OD2-CB 3.35Å; D42-K69 PolarHBondContact OD2-N 3.07Å; K69-K72 VanDerWaalsContact O-CE 3.3Å; K69-K72 WeakPolarHBondContact O-CE 3.43Å; K69-K72 PolarHBondContact O-NZ 3.37Å
70S97.3Very high94.7Very high36 Ų3660.9 Ų60.925%0.25231%0.31SS..SBendtrans-97.1-31.1-177.253.50000112.2D42 D46 K72D42-S70 WeakPolarHBondContact CA-OG 3.26Å; D42-S70 WeakPolarHBondContact CB-OG 3.43Å; D42-S70 PolarHBondContact O-OG 2.91Å; D42-S70 PolarHBondContact OD1-N 3.44Å; D42-S70 PolarHBondContact OD1-OG 3.18Å; D46-S70 WeakPolarHBondContact OD1-CB 3.46Å; D46-S70 PolarHBondContact OD1-OG 3.35Å; S70-K72 PolarHBondContact O-N 2.95Å
71T98.1Very high94.6Very high4 Ų461.4 Ų61.43%0.02532%0.317CS..  trans-72.6114.8175.7-43.80000110.5A41 D42 T45 V51 V53A41-T71 HydrophobicContact CB-CG2 4.41Å; A41-T71 PolarHBondContact O-OG1 3.43Å; A41-T71 VanDerWaalsContact O-OG1 3.14Å; D42-T71 WeakPolarHBondContact CA-OG1 3.41Å; D42-T71 PolarHBondContact N-OG1 3.09Å; D42-T71 WeakPolarHBondContact OD1-CB 3.39Å; D42-T71 PolarHBondContact OD1-N 3.45Å; D42-T71 PolarHBondContact OD1-OG1 3.48Å; T45-T71 PolarHBondContact OG1-OG1 2.87Å; V51-T71 HydrophobicContact CB-CG2 4.01Å; V51-T71 HydrophobicContact CG1-CG2 4.02Å; V53-T71 HydrophobicContact CG2-CG2 3.72Å
72K97.4Very high94.7Very high159 Ų15961.1 Ų61.169%0.69132%0.316SS*.  trans-106.5-21.1-177.1-57.7-50.2-173.3-175.70114.5K69 S70 T74K69-K72 VanDerWaalsContact O-CE 3.3Å; K69-K72 WeakPolarHBondContact O-CE 3.43Å; K69-K72 PolarHBondContact O-NZ 3.37Å; S70-K72 PolarHBondContact O-N 2.95Å; K72-T74 PolarHBondContact O-N 2.81Å
73N97.8Very high94.7Very high75 Ų7560.5 Ų60.540%0.40131%0.312SS..EExtended strand (participates in β ladder)trans-81.391.6-177.9-170.316.3000110.1T52 V53T52-N73 CarbonylContact C-O 3.4Å; T52-N73 WeakPolarHBondContact CA-O 3.49Å; T52-N73 PolarHBondContact OG1-ND2 2.83Å; V53-N73 PolarHBondContact N-O 3.13Å
74T98Very high94.6Very high48 Ų4860.6 Ų60.629%0.29432%0.316SS..EExtended strand (participates in β ladder)trans-117.7135.4-177.856.70000111.1V53 M55 L68 K72 F76V53-T74 HydrophobicContact CB-CG2 4.49Å; V53-T74 CarbonylContact O-C 3.59Å; V53-T74 VanDerWaalsContact O-CA 3.32Å; V53-T74 WeakPolarHBondContact O-CA 3.38Å; M55-T74 HydrophobicContact SD-CG2 4.38Å; L68-T74 HydrophobicContact CD1-CG2 3.49Å; L68-T74 VanDerWaalsContact CD1-CG2 3.49Å; K72-T74 PolarHBondContact O-N 2.81Å; T74-F76 WeakPolarHBondContact OG1-CE2 3.42Å
75I98.3Very high94.6Very high23 Ų2359.6 Ų59.612%0.11831%0.306CS..EExtended strand (participates in β ladder)trans-113.1122.3171.7-58172.1000106.9T52 V53 L54 M55 L132 L136T52-I75 HydrophobicContact CG2-CD1 3.79Å; T52-I75 HydrophobicContact CG2-CG1 4.11Å; V53-I75 PolarHBondContact O-N 2.81Å; L54-I75 CarbonylContact C-O 3.54Å; L54-I75 WeakPolarHBondContact CA-O 3.28Å; L54-I75 HydrophobicContact CD1-CB 3.9Å; L54-I75 HydrophobicContact CD1-CG2 3.68Å; M55-I75 PolarHBondContact N-O 3.29Å; I75-L132 HydrophobicContact CG2-CD1 3.9Å; I75-L136 HydrophobicContact CD1-CD2 3.97Å
76F98.1Very high94.6Very high53 Ų5354.9 Ų54.923%0.23229%0.287CS..EExtended strand (participates in β ladder)trans-100.2140175.2-65.4-84.9000110.1L28 M55 V57 R63 T66 T74L28-F76 HydrophobicContact CD1-CD1 4.35Å; L28-F76 HydrophobicContact CD1-CE1 4.13Å; M55-F76 HydrophobicContact CB-CD1 3.82Å; M55-F76 HydrophobicContact CB-CE1 3.94Å; M55-F76 HydrophobicContact CG-CE1 4.43Å; M55-F76 WeakPolarHBondContact O-CA 3.43Å; M55-F76 HydrophobicContact SD-CE1 3.88Å; M55-F76 HydrophobicContact SD-CZ 4.21Å; V57-F76 HydrophobicContact CG2-CD1 4.2Å; R63-F76 VanDerWaalsContact CZ-CD1 3.45Å; R63-F76 VanDerWaalsContact NH1-CZ 3.3Å; R63-F76 VanDerWaalsContact NH2-CD2 3.35Å; R63-F76 VanDerWaalsContact NH2-CG 3.29Å; T66-F76 HydrophobicContact CG2-CE1 3.91Å; T66-F76 HydrophobicContact CG2-CZ 3.88Å; T74-F76 WeakPolarHBondContact OG1-CE2 3.42Å
77V98.1Very high94.3Very high1 Ų154.1 Ų54.11%0.00628%0.282CS..EExtended strand (participates in β ladder)trans-117.4114.5164.6178.60000106.4L54 M55 P56 V57 K125 V126 E129 L132L54-V77 HydrophobicContact CD1-CG2 3.84Å; M55-V77 PolarHBondContact O-N 3.34Å; P56-V77 CarbonylContact C-O 3.53Å; P56-V77 WeakPolarHBondContact CA-O 3.33Å; V57-V77 WeakPolarHBondContact CG2-O 3.38Å; V57-V77 PolarHBondContact N-O 2.88Å; V77-K125 HydrophobicContact CG1-CG 3.97Å; V77-V126 HydrophobicContact CB-CG2 4.14Å; V77-V126 HydrophobicContact CG1-CG2 3.97Å; V77-V126 HydrophobicContact CG2-CG2 4.44Å; V77-E129 HydrophobicContact CG1-CB 4.38Å; V77-E129 HydrophobicContact CG1-CG 4.4Å; V77-E129 HydrophobicContact CG2-CB 4.44Å; V77-E129 HydrophobicContact CG2-CG 4.22Å; V77-L132 HydrophobicContact CG2-CD2 3.72Å
78E96.6Very high94Very high83 Ų8354.9 Ų54.939%0.38829%0.287SS..PPolyproline II helixtrans-65.8162.2-176.9-57.4-57.6151.300111.5R63 Q122 K125R63-E78 IonicContact CZ-OE1 3.63Å; R63-E78 IonicContact NE-OE1 3.21Å; R63-E78 PolarHBondContact NE-OE1 3.43Å; R63-E78 IonicContact NE-OE2 3.86Å; R63-E78 IonicContact NH2-OE1 3.73Å; R63-E78 PolarHBondContact NH2-OE1 3.26Å; E78-Q122 PolarHBondContact O-NE2 2.89Å; E78-K125 WeakPolarHBondContact O-CG 3.25Å
79A95.4Very high93.6Very high29 Ų2957.9 Ų57.924%0.2430%0.303CS..PPolyproline II helixtrans-55.7138.8-175.200000112.3V57 V83V57-A79 VanDerWaalsContact O-CA 3.22Å; V57-A79 WeakPolarHBondContact O-CA 3.48Å; V57-A79 WeakPolarHBondContact O-CB 3.24Å; V57-A79 PolarHBondContact O-N 2.92Å; A79-V83 HydrophobicContact CB-CB 4.23Å; A79-V83 HydrophobicContact CB-CG1 4.3Å
80G91.7Very high93.1Very high9 Ų951.8 Ų51.89%0.09328%0.277CS..PPolyproline II helixtrans-65.4169.6170.800000112.3V83G80-V83 PolarHBondContact O-N 3.12Å
81P87.9Confident92.7Very high84 Ų8453.9 Ų53.955%0.54528%0.279SS..THydrogen-bonded Turntrans-52.3145.1169-18.831.1000110.3V83 E121P81-V83 PolarHBondContact O-N 3.3Å; P81-E121 WeakPolarHBondContact CB-OE1 3.43Å; P81-E121 WeakPolarHBondContact O-CG 3.39Å; P81-E121 VanDerWaalsContact O-OE1 3.08Å
82N89.4Confident92.1Very high95 Ų9558.9 Ų58.951%0.50830%0.303SS..THydrogen-bonded Turntrans61.6-9.9177.3-42.7-45.3000117.2E84 E85 L86N82-E84 VanDerWaalsContact C-N 3.29Å; N82-E84 PolarHBondContact O-N 2.87Å; N82-E85 WeakPolarHBondContact O-CB 3.46Å; N82-E85 PolarHBondContact O-N 2.88Å; N82-E85 VanDerWaalsContact O-N 3.07Å; N82-L86 WeakPolarHBondContact O-CG 3.35Å; N82-L86 PolarHBondContact O-N 2.91Å
83V90.8Very high91.6Very high0 Ų053.5 Ų53.50%028%0.279CS..Hα-helixtrans-60.6-38.5-178.9173.30000111.3F58 A79 G80 P81 E85 L86 M87 E121 Q122F58-V83 HydrophobicContact CB-CG1 4.44Å; F58-V83 HydrophobicContact CD1-CG1 4.04Å; F58-V83 HydrophobicContact CG-CG1 4.46Å; A79-V83 HydrophobicContact CB-CB 4.23Å; A79-V83 HydrophobicContact CB-CG1 4.3Å; G80-V83 PolarHBondContact O-N 3.12Å; P81-V83 PolarHBondContact O-N 3.3Å; V83-E85 PolarHBondContact O-N 2.71Å; V83-L86 PolarHBondContact O-N 3.33Å; V83-M87 HydrophobicContact CG1-CG 4.31Å; V83-M87 WeakPolarHBondContact O-CB 3.24Å; V83-M87 VanDerWaalsContact O-CG 3.26Å; V83-M87 WeakPolarHBondContact O-CG 3.42Å; V83-M87 PolarHBondContact O-N 2.99Å; V83-E121 HydrophobicContact CG2-CB 4.15Å; V83-E121 HydrophobicContact CG2-CG 3.84Å; V83-Q122 HydrophobicContact CG2-CB 4.24Å
84E89.3Confident91.1Very high66 Ų6651.4 Ų51.431%0.30827%0.268SS..Hα-helixtrans-65.8-36.4175.9-175.260.4-126.700112.7N60 N82 M87 S88 R91N60-E84 PolarHBondContact ND2-OE2 2.72Å; N82-E84 VanDerWaalsContact C-N 3.29Å; N82-E84 PolarHBondContact O-N 2.87Å; E84-M87 PolarHBondContact O-N 3.21Å; E84-S88 PolarHBondContact O-N 3.41Å; E84-R91 IonicContact OE1-CZ 2.93Å; E84-R91 IonicContact OE1-NH1 2.99Å; E84-R91 PolarHBondContact OE1-NH1 3.43Å; E84-R91 IonicContact OE1-NH2 3.09Å; E84-R91 PolarHBondContact OE1-NH2 3.41Å
85E90.4Very high90.7Very high128 Ų12849.8 Ų49.860%0.59826%0.26SS*.Hα-helixtrans-65.4-47.2174.8-176.7176.1-176.300110.4N82 V83 M87 S88 D89N82-E85 WeakPolarHBondContact O-CB 3.46Å; N82-E85 PolarHBondContact O-N 2.88Å; N82-E85 VanDerWaalsContact O-N 3.07Å; V83-E85 PolarHBondContact O-N 2.71Å; E85-M87 VanDerWaalsContact C-N 3.3Å; E85-M87 PolarHBondContact O-N 3.33Å; E85-S88 WeakPolarHBondContact O-CA 3.46Å; E85-S88 WeakPolarHBondContact O-CB 3.37Å; E85-S88 PolarHBondContact O-N 3.13Å; E85-D89 PolarHBondContact O-N 2.92Å
86L90Very high90.3Very high30 Ų3050.5 Ų50.516%0.15726%0.264CS..Hα-helixtrans-62.2-36.6175.8-66.8166.9000112.3N82 V83 S88 D89 M90 T117 A118N82-L86 WeakPolarHBondContact O-CG 3.35Å; N82-L86 PolarHBondContact O-N 2.91Å; V83-L86 PolarHBondContact O-N 3.33Å; L86-S88 VanDerWaalsContact C-N 3.29Å; L86-S88 PolarHBondContact O-N 3.43Å; L86-D89 PolarHBondContact O-N 2.91Å; L86-M90 PolarHBondContact O-N 3Å; L86-T117 HydrophobicContact CD1-CG2 4.1Å; L86-A118 HydrophobicContact CB-CB 3.9Å; L86-A118 HydrophobicContact CD1-CB 3.83Å; L86-A118 HydrophobicContact CG-CB 4.41Å
87M89.3Confident89.9Confident8 Ų848 Ų484%0.03925%0.253CS..Hα-helixtrans-68.5-29.1172.1-72.2-48.4-58.600112.3F29 F58 D59 V83 E84 E85 M90 R91F29-M87 HydrophobicContact CD2-CE 3.72Å; F29-M87 HydrophobicContact CD2-SD 3.72Å; F29-M87 HydrophobicContact CE2-CE 3.72Å; F29-M87 HydrophobicContact CE2-SD 3.79Å; F58-M87 HydrophobicContact CB-CG 4.44Å; F58-M87 HydrophobicContact CB-SD 4.17Å; F58-M87 HydrophobicContact CD1-SD 4.37Å; F58-M87 WeakPolarHBondContact O-CG 3.48Å; D59-M87 HydrophobicContact CB-CE 4.28Å; V83-M87 HydrophobicContact CG1-CG 4.31Å; V83-M87 WeakPolarHBondContact O-CB 3.24Å; V83-M87 VanDerWaalsContact O-CG 3.26Å; V83-M87 WeakPolarHBondContact O-CG 3.42Å; V83-M87 PolarHBondContact O-N 2.99Å; E84-M87 PolarHBondContact O-N 3.21Å; E85-M87 VanDerWaalsContact C-N 3.3Å; E85-M87 PolarHBondContact O-N 3.33Å; M87-M90 HydrophobicContact CE-CB 4.35Å; M87-M90 HydrophobicContact CE-CG 4.4Å; M87-M90 WeakPolarHBondContact O-CB 3.32Å; M87-M90 PolarHBondContact O-N 3.18Å; M87-R91 VanDerWaalsContact O-CG 3.3Å; M87-R91 WeakPolarHBondContact O-CG 3.42Å; M87-R91 PolarHBondContact O-N 3.34Å; M87-R91 PolarHBondContact O-NE 3.09Å
88S88Confident89.7Confident56 Ų5648 Ų4839%0.39225%0.253SS..Hα-helixtrans-65.7-45.9170.8-160.60000111.7E84 E85 L86 M90 R91 Q92E84-S88 PolarHBondContact O-N 3.41Å; E85-S88 WeakPolarHBondContact O-CA 3.46Å; E85-S88 WeakPolarHBondContact O-CB 3.37Å; E85-S88 PolarHBondContact O-N 3.13Å; L86-S88 VanDerWaalsContact C-N 3.29Å; L86-S88 PolarHBondContact O-N 3.43Å; S88-M90 VanDerWaalsContact C-N 3.29Å; S88-M90 PolarHBondContact O-N 3.24Å; S88-R91 VanDerWaalsContact CA-NH2 3.26Å; S88-R91 WeakPolarHBondContact O-CB 3.3Å; S88-R91 PolarHBondContact O-N 3.34Å; S88-R91 VanDerWaalsContact O-N 3.15Å; S88-Q92 PolarHBondContact O-N 3.39Å
89D87.3Confident89.3Confident87 Ų8750.7 Ų50.747%0.46526%0.263SS..Hα-helixtrans-61.8-39.1175.1-68.7-18.7000111.4E85 L86 R91 Q92 F93E85-D89 PolarHBondContact O-N 2.92Å; L86-D89 PolarHBondContact O-N 2.91Å; D89-R91 PolarHBondContact O-N 2.83Å; D89-Q92 WeakPolarHBondContact O-CB 3.17Å; D89-Q92 PolarHBondContact O-N 2.97Å; D89-F93 PolarHBondContact O-N 3.49Å
90M86.3Confident88.9Confident13 Ų1352.8 Ų52.86%0.06427%0.268CS..Hα-helixtrans-59.7-44.2173.1-165.764.266.400112.4F29 L86 M87 S88 Q92 F93 L94 M115F29-M90 HydrophobicContact CE2-CE 4.26Å; F29-M90 HydrophobicContact CE2-CG 4.37Å; F29-M90 HydrophobicContact CZ-CE 4.34Å; L86-M90 PolarHBondContact O-N 3Å; M87-M90 HydrophobicContact CE-CB 4.35Å; M87-M90 HydrophobicContact CE-CG 4.4Å; M87-M90 WeakPolarHBondContact O-CB 3.32Å; M87-M90 PolarHBondContact O-N 3.18Å; S88-M90 VanDerWaalsContact C-N 3.29Å; S88-M90 PolarHBondContact O-N 3.24Å; M90-Q92 VanDerWaalsContact C-N 3.28Å; M90-Q92 PolarHBondContact O-N 3.44Å; M90-F93 WeakPolarHBondContact O-CB 3.46Å; M90-F93 PolarHBondContact O-N 2.89Å; M90-L94 HydrophobicContact CG-CD1 4.47Å; M90-L94 VanDerWaalsContact O-CG 3.31Å; M90-L94 WeakPolarHBondContact O-CG 3.4Å; M90-L94 PolarHBondContact O-N 3.08Å; M90-M115 HydrophobicContact CE-CB 4.38Å; M90-M115 HydrophobicContact CE-CE 3.67Å; M90-M115 HydrophobicContact CE-CG 3.26Å; M90-M115 HydrophobicContact CE-SD 4.3Å; M90-M115 HydrophobicContact SD-CE 3.44Å; M90-M115 WeakPolarHBondContact SD-CE 3.3Å; M90-M115 HydrophobicContact SD-CG 4.29Å
91R87.5Confident88.4Confident80 Ų8057 Ų5730%0.30229%0.288SS..Hα-helixtrans-63.1-38.2176.9-72.8177.4-61.8-112.96.7110.8E84 M87 S88 D89 L94 A95E84-R91 IonicContact OE1-CZ 2.93Å; E84-R91 IonicContact OE1-NH1 2.99Å; E84-R91 PolarHBondContact OE1-NH1 3.43Å; E84-R91 IonicContact OE1-NH2 3.09Å; E84-R91 PolarHBondContact OE1-NH2 3.41Å; M87-R91 VanDerWaalsContact O-CG 3.3Å; M87-R91 WeakPolarHBondContact O-CG 3.42Å; M87-R91 PolarHBondContact O-N 3.34Å; M87-R91 PolarHBondContact O-NE 3.09Å; S88-R91 VanDerWaalsContact CA-NH2 3.26Å; S88-R91 WeakPolarHBondContact O-CB 3.3Å; S88-R91 PolarHBondContact O-N 3.34Å; S88-R91 VanDerWaalsContact O-N 3.15Å; D89-R91 PolarHBondContact O-N 2.83Å; R91-L94 PolarHBondContact O-N 2.92Å; R91-A95 WeakPolarHBondContact O-CB 3.19Å; R91-A95 PolarHBondContact O-N 3.45Å
92Q87.1Confident88Confident110 Ų11053.6 Ų53.651%0.51427%0.266SS..Hα-helixtrans-66.3-41.7174.8-171.760.657.600111.9S88 D89 M90 L94 A95 N96S88-Q92 PolarHBondContact O-N 3.39Å; D89-Q92 WeakPolarHBondContact O-CB 3.17Å; D89-Q92 PolarHBondContact O-N 2.97Å; M90-Q92 VanDerWaalsContact C-N 3.28Å; M90-Q92 PolarHBondContact O-N 3.44Å; Q92-L94 PolarHBondContact O-N 2.97Å; Q92-A95 PolarHBondContact O-N 3.29Å; Q92-N96 PolarHBondContact NE2-OD1 2.86Å; Q92-N96 WeakPolarHBondContact O-CB 3.47Å; Q92-N96 VanDerWaalsContact O-CG 3.3Å; Q92-N96 PolarHBondContact O-N 3.42Å; Q92-N96 PolarHBondContact O-OD1 2.96Å
93F86.4Confident87.3Confident46 Ų4651 Ų5120%0.20226%0.262CS..Hα-helixtrans-58.3-46.3173.5172.6-97.4000111.6D89 M90 A95 N96 A97 T102 T107 A111D89-F93 PolarHBondContact O-N 3.49Å; M90-F93 WeakPolarHBondContact O-CB 3.46Å; M90-F93 PolarHBondContact O-N 2.89Å; F93-A95 PolarHBondContact O-N 3.06Å; F93-N96 CarbonylContact O-C 3.58Å; F93-N96 PolarHBondContact O-N 3.47Å; F93-A97 PolarHBondContact O-N 3.19Å; F93-T102 HydrophobicContact CZ-CG2 4.46Å; F93-T107 HydrophobicContact CE2-CG2 3.86Å; F93-A111 HydrophobicContact CE2-CB 4.04Å; F93-A111 HydrophobicContact CZ-CB 4.06Å
94L87.7Confident86.7Confident30 Ų3053.7 Ų53.716%0.15728%0.276CS..Hα-helixtrans-64.4-38177.4-68.3171.7000112.6M90 R91 Q92 N96 A97 N308 F397M90-L94 HydrophobicContact CG-CD1 4.47Å; M90-L94 VanDerWaalsContact O-CG 3.31Å; M90-L94 WeakPolarHBondContact O-CG 3.4Å; M90-L94 PolarHBondContact O-N 3.08Å; R91-L94 PolarHBondContact O-N 2.92Å; Q92-L94 PolarHBondContact O-N 2.97Å; L94-N96 VanDerWaalsContact C-N 3.34Å; L94-A97 VanDerWaalsContact O-CB 3.32Å; L94-A97 WeakPolarHBondContact O-CB 3.35Å; L94-A97 PolarHBondContact O-N 3.02Å; L94-N308 HydrophobicContact CD1-CB 4.22Å; L94-F397 HydrophobicContact CD2-CD2 4.29Å; L94-F397 HydrophobicContact CD2-CE1 4.1Å; L94-F397 HydrophobicContact CD2-CE2 3.65Å; L94-F397 HydrophobicContact CD2-CZ 3.55Å
95A88.3Confident86.2Confident15 Ų1554.4 Ų54.412%0.12429%0.287CS..Hα-helixtrans-65-38.9173.100000111.6R91 Q92 F93 A97 D313R91-A95 WeakPolarHBondContact O-CB 3.19Å; R91-A95 PolarHBondContact O-N 3.45Å; Q92-A95 PolarHBondContact O-N 3.29Å; F93-A95 PolarHBondContact O-N 3.06Å; A95-A97 VanDerWaalsContact C-N 3.27Å; A95-A97 PolarHBondContact O-N 3.14Å; A95-D313 HydrophobicContact CB-CB 4.13Å
96N89.9Confident85.8Confident38 Ų3854.7 Ų54.720%0.20329%0.291CS..Hα-helixtrans-72.1-17.1177.4-73.43.5000113.5Q92 F93 L94 W98 K99 E100Q92-N96 PolarHBondContact NE2-OD1 2.86Å; Q92-N96 WeakPolarHBondContact O-CB 3.47Å; Q92-N96 VanDerWaalsContact O-CG 3.3Å; Q92-N96 PolarHBondContact O-N 3.42Å; Q92-N96 PolarHBondContact O-OD1 2.96Å; F93-N96 CarbonylContact O-C 3.58Å; F93-N96 PolarHBondContact O-N 3.47Å; L94-N96 VanDerWaalsContact C-N 3.34Å; N96-W98 PolarHBondContact O-N 2.84Å; N96-K99 WeakPolarHBondContact O-CA 3.41Å; N96-K99 PolarHBondContact O-N 3.13Å; N96-E100 HydrophobicContact CB-CG 4.14Å; N96-E100 WeakPolarHBondContact CB-OE1 3.48Å; N96-E100 PolarHBondContact ND2-OE1 3.38Å; N96-E100 PolarHBondContact O-N 3.05Å
97A91.5Very high85.4Confident1 Ų154.9 Ų54.91%0.00829%0.293CS..THydrogen-bonded Turntrans-58.9-22.2179.600000113.6F93 L94 A95 K99 T102 F397 K418F93-A97 PolarHBondContact O-N 3.19Å; L94-A97 VanDerWaalsContact O-CB 3.32Å; L94-A97 WeakPolarHBondContact O-CB 3.35Å; L94-A97 PolarHBondContact O-N 3.02Å; A95-A97 VanDerWaalsContact C-N 3.27Å; A95-A97 PolarHBondContact O-N 3.14Å; A97-K99 VanDerWaalsContact C-N 3.31Å; A97-T102 HydrophobicContact CB-CG2 3.83Å; A97-F397 HydrophobicContact CB-CB 4.48Å; A97-F397 HydrophobicContact CB-CD1 3.57Å; A97-F397 HydrophobicContact CB-CE1 4.16Å; A97-F397 HydrophobicContact CB-CG 4.34Å; A97-K418 PolarHBondContact O-NZ 3.45Å
98W92.5Very high85.1Confident0 Ų055.3 Ų55.30%030%0.295CS..THydrogen-bonded Turntrans-65.4-31.9170.1-72.4113.5000113.8N96 F305 A309 K310 M314 P315 F318 L396 L421N96-W98 PolarHBondContact O-N 2.84Å; W98-F305 HydrophobicContact CH2-CB 3.96Å; W98-F305 AromaticContact CH2-CD1 3.45Å; W98-F305 HydrophobicContact CH2-CD1 3.45Å; W98-F305 VanDerWaalsContact CH2-CD1 3.45Å; W98-F305 AromaticContact CH2-CD2 3.65Å; W98-F305 HydrophobicContact CH2-CD2 3.65Å; W98-F305 AromaticContact CH2-CE1 3.71Å; W98-F305 HydrophobicContact CH2-CE1 3.71Å; W98-F305 AromaticContact CH2-CE2 3.9Å; W98-F305 HydrophobicContact CH2-CE2 3.9Å; W98-F305 AromaticContact CH2-CG 3.4Å; W98-F305 HydrophobicContact CH2-CG 3.4Å; W98-F305 VanDerWaalsContact CH2-CG 3.4Å; W98-F305 AromaticContact CH2-CZ 3.94Å; W98-F305 HydrophobicContact CH2-CZ 3.94Å; W98-F305 HydrophobicContact CZ2-CB 3.87Å; W98-F305 HydrophobicContact CZ2-CD1 4.23Å; W98-F305 HydrophobicContact CZ2-CD2 4.11Å; W98-F305 AromaticContact CZ2-CG 3.82Å; W98-F305 HydrophobicContact CZ2-CG 3.82Å; W98-F305 HydrophobicContact CZ3-CD1 4.22Å; W98-F305 HydrophobicContact CZ3-CE1 4.18Å; W98-F305 HydrophobicContact CZ3-CZ 4.47Å; W98-A309 HydrophobicContact CZ2-CB 4.14Å; W98-K310 PolarHBondContact NE1-O 3.29Å; W98-M314 HydrophobicContact CD2-CB 4.29Å; W98-M314 HydrophobicContact CD2-CG 4.42Å; W98-M314 HydrophobicContact CE3-CE 4.42Å; W98-M314 HydrophobicContact CE3-CG 4.22Å; W98-M314 HydrophobicContact CH2-CE 3.35Å; W98-M314 HydrophobicContact CZ2-CB 4.47Å; W98-M314 HydrophobicContact CZ2-CE 4.01Å; W98-M314 HydrophobicContact CZ3-CE 3.61Å; W98-M314 HydrophobicContact CZ3-CG 4.3Å; W98-P315 HydrophobicContact CB-CG 4.48Å; W98-F318 HydrophobicContact CE3-CD2 4.22Å; W98-F318 HydrophobicContact CE3-CE2 4.35Å; W98-L396 HydrophobicContact CD2-CD1 4.15Å; W98-L396 HydrophobicContact CD2-CD2 4.38Å; W98-L396 HydrophobicContact CE3-CD1 4.08Å; W98-L396 HydrophobicContact CE3-CD2 3.66Å; W98-L396 HydrophobicContact CH2-CD1 3.79Å; W98-L396 HydrophobicContact CH2-CD2 4.38Å; W98-L396 HydrophobicContact CZ2-CD1 3.85Å; W98-L396 HydrophobicContact CZ3-CD1 3.89Å; W98-L396 HydrophobicContact CZ3-CD2 3.66Å; W98-L396 HydrophobicContact CZ3-CG 4.42Å; W98-L421 HydrophobicContact CZ3-CD1 3.76Å
99K89.4Confident84.9Confident140 Ų14055.6 Ų55.661%0.60929%0.291SS*.THydrogen-bonded Turntrans-106.1-39.4-170.9-63.4174-173.7174.10112.7N96 A97 P315N96-K99 WeakPolarHBondContact O-CA 3.41Å; N96-K99 PolarHBondContact O-N 3.13Å; A97-K99 VanDerWaalsContact C-N 3.31Å; K99-P315 HydrophobicContact CG-CG 3.83Å
100E85.5Confident84.8Confident72 Ų7257.8 Ų57.834%0.33630%0.296SS..SBendtrans-89.3147.2-172.6-67.8-179.6-165.300111.8N96 T102 K418N96-E100 HydrophobicContact CB-CG 4.14Å; N96-E100 WeakPolarHBondContact CB-OE1 3.48Å; N96-E100 PolarHBondContact ND2-OE1 3.38Å; N96-E100 PolarHBondContact O-N 3.05Å; E100-T102 PolarHBondContact O-N 2.92Å; E100-T102 VanDerWaalsContact O-N 3.09Å; E100-K418 PolarHBondContact O-NZ 2.95Å
101D82.7Confident84.8Confident97 Ų9757.6 Ų57.652%0.51930%0.297SS..  trans-71.9100166.3179.211.1000109.7G103 N104D101-G103 PolarHBondContact O-N 2.79Å; D101-G103 WeakPolarHBondContact OD1-CA 3.21Å; D101-G103 PolarHBondContact OD1-N 2.84Å; D101-N104 HydrophobicContact CB-CB 4.38Å; D101-N104 VanDerWaalsContact O-CB 3.26Å; D101-N104 WeakPolarHBondContact O-CB 3.44Å; D101-N104 PolarHBondContact O-N 3.13Å
102T79.6Confident84.8Confident14 Ų1453.8 Ų53.89%0.08628%0.283CS..THydrogen-bonded Turntrans-75.5-12.4179.754.60000112.5F93 A97 E100 N104 M108 L396 F397F93-T102 HydrophobicContact CZ-CG2 4.46Å; A97-T102 HydrophobicContact CB-CG2 3.83Å; E100-T102 PolarHBondContact O-N 2.92Å; E100-T102 VanDerWaalsContact O-N 3.09Å; T102-N104 VanDerWaalsContact C-N 3.32Å; T102-M108 VanDerWaalsContact O-CG 3.28Å; T102-M108 WeakPolarHBondContact O-CG 3.12Å; T102-L396 PolarHBondContact OG1-O 2.85Å; T102-F397 HydrophobicContact CG2-CB 4.04Å
103G74.7Confident84.9Confident40 Ų4052.9 Ų52.941%0.41228%0.279SS..THydrogen-bonded Turntrans-82.9-7.3170.900000113.4D101 P105D101-G103 PolarHBondContact O-N 2.79Å; D101-G103 WeakPolarHBondContact OD1-CA 3.21Å; D101-G103 PolarHBondContact OD1-N 2.84Å; G103-P105 WeakPolarHBondContact O-CD 3.29Å
104N78.4Confident85Confident56 Ų5653.6 Ų53.630%0.29929%0.285SS..  trans-64.6125.2178-174.1-63.4000110.9D101 T102 I106 T107 M108D101-N104 HydrophobicContact CB-CB 4.38Å; D101-N104 VanDerWaalsContact O-CB 3.26Å; D101-N104 WeakPolarHBondContact O-CB 3.44Å; D101-N104 PolarHBondContact O-N 3.13Å; T102-N104 VanDerWaalsContact C-N 3.32Å; N104-I106 PolarHBondContact O-N 3.42Å; N104-I106 VanDerWaalsContact O-N 3.13Å; N104-I106 VanDerWaalsContact OD1-CB 3.3Å; N104-I106 WeakPolarHBondContact OD1-CB 3.13Å; N104-I106 PolarHBondContact OD1-N 3.3Å; N104-T107 PolarHBondContact O-N 2.92Å; N104-T107 VanDerWaalsContact O-N 3.13Å; N104-M108 WeakPolarHBondContact O-CG 3.3Å; N104-M108 PolarHBondContact O-N 3.25Å
105P77.5Confident85.2Confident82 Ų8253.3 Ų53.353%0.53228%0.283SS..Hα-helixtrans-57.8-31-177.7-27.335000114.9G103 M109G103-P105 WeakPolarHBondContact O-CD 3.29Å; P105-M109 WeakPolarHBondContact O-CB 3.32Å; P105-M109 PolarHBondContact O-N 2.96Å
106I82Confident85.4Confident134 Ų13452.6 Ų52.669%0.68728%0.277SS*.Hα-helixtrans-71.1-47.9178.1-59174.3000109.9N104 M108 M109 K110N104-I106 PolarHBondContact O-N 3.42Å; N104-I106 VanDerWaalsContact O-N 3.13Å; N104-I106 VanDerWaalsContact OD1-CB 3.3Å; N104-I106 WeakPolarHBondContact OD1-CB 3.13Å; N104-I106 PolarHBondContact OD1-N 3.3Å; I106-M108 VanDerWaalsContact C-N 3.31Å; I106-M108 PolarHBondContact O-N 3.07Å; I106-M109 PolarHBondContact O-N 2.67Å; I106-K110 PolarHBondContact O-N 3.27Å
107T82.7Confident85.6Confident33 Ų3353.5 Ų53.520%0.20228%0.284CS..Hα-helixtrans-59.2-45.1175.8-57.20000110.6F93 N104 K110 A111F93-T107 HydrophobicContact CE2-CG2 3.86Å; N104-T107 PolarHBondContact O-N 2.92Å; N104-T107 VanDerWaalsContact O-N 3.13Å; T107-K110 PolarHBondContact O-N 2.95Å; T107-A111 WeakPolarHBondContact O-CB 3.34Å; T107-A111 PolarHBondContact O-N 2.76Å
108M81.3Confident85.7Confident17 Ų1753.5 Ų53.58%0.08428%0.284CS..Hα-helixtrans-60.7-45.4174.5-68-18071.500111.8T102 N104 I106 K110 A111 A112 Q194 V215 F219T102-M108 VanDerWaalsContact O-CG 3.28Å; T102-M108 WeakPolarHBondContact O-CG 3.12Å; N104-M108 WeakPolarHBondContact O-CG 3.3Å; N104-M108 PolarHBondContact O-N 3.25Å; I106-M108 VanDerWaalsContact C-N 3.31Å; I106-M108 PolarHBondContact O-N 3.07Å; M108-K110 PolarHBondContact O-N 2.67Å; M108-A111 PolarHBondContact O-N 2.72Å; M108-A112 WeakPolarHBondContact O-CB 3.39Å; M108-A112 PolarHBondContact O-N 3.34Å; M108-Q194 VanDerWaalsContact CE-NE2 3.25Å; M108-V215 HydrophobicContact CE-CG1 4.26Å; M108-F219 WeakPolarHBondContact O-CD2 3.33Å; M108-F219 WeakPolarHBondContact O-CE2 3.48Å
109M85Confident85.9Confident62 Ų6253.6 Ų53.631%0.30528%0.284SS..Hα-helixtrans-63.7-41.3-179.5-169.660.560.800112.1P105 I106 A112 Q113 Y218P105-M109 WeakPolarHBondContact O-CB 3.32Å; P105-M109 PolarHBondContact O-N 2.96Å; I106-M109 PolarHBondContact O-N 2.67Å; M109-A112 WeakPolarHBondContact O-CB 3.29Å; M109-A112 PolarHBondContact O-N 2.98Å; M109-Q113 WeakPolarHBondContact O-CG 3.33Å; M109-Q113 PolarHBondContact O-N 3.48Å; M109-Y218 HydrophobicContact CE-CD1 3.8Å; M109-Y218 HydrophobicContact CE-CE1 3.64Å; M109-Y218 HydrophobicContact SD-CD1 4.38Å; M109-Y218 HydrophobicContact SD-CE1 3.83Å
110K85.5Confident86.2Confident133 Ų13347.6 Ų47.658%0.57826%0.261SS*.Hα-helixtrans-62.3-47.8174.8-176.3178.6176.5-172.70110.9I106 T107 M108 A112 Q113 D114I106-K110 PolarHBondContact O-N 3.27Å; T107-K110 PolarHBondContact O-N 2.95Å; M108-K110 PolarHBondContact O-N 2.67Å; K110-A112 PolarHBondContact O-N 2.8Å; K110-Q113 WeakPolarHBondContact O-CB 3.45Å; K110-Q113 PolarHBondContact O-N 2.93Å; K110-Q113 VanDerWaalsContact O-N 3.07Å; K110-D114 PolarHBondContact O-N 3.32Å
111A85.5Confident86.7Confident10 Ų1046.9 Ų46.98%0.08326%0.258CS..Hα-helixtrans-58.9-36175.400000112.3F93 T107 M108 D114 M115 F219F93-A111 HydrophobicContact CE2-CB 4.04Å; F93-A111 HydrophobicContact CZ-CB 4.06Å; T107-A111 WeakPolarHBondContact O-CB 3.34Å; T107-A111 PolarHBondContact O-N 2.76Å; M108-A111 PolarHBondContact O-N 2.72Å; A111-D114 PolarHBondContact O-N 2.79Å; A111-M115 VanDerWaalsContact O-CB 3.27Å; A111-M115 WeakPolarHBondContact O-CB 3.37Å; A111-M115 VanDerWaalsContact O-CG 3.32Å; A111-M115 WeakPolarHBondContact O-CG 3.21Å; A111-M115 PolarHBondContact O-N 3.22Å; A111-F219 HydrophobicContact CB-CE2 4.23Å
112A87.1Confident87.4Confident0 Ų042.2 Ų42.20%023%0.233CC..Hα-helixtrans-63.7-42.1175.400000111.8M108 M109 K110 G116 F219 L222M108-A112 WeakPolarHBondContact O-CB 3.39Å; M108-A112 PolarHBondContact O-N 3.34Å; M109-A112 WeakPolarHBondContact O-CB 3.29Å; M109-A112 PolarHBondContact O-N 2.98Å; K110-A112 PolarHBondContact O-N 2.8Å; A112-G116 WeakPolarHBondContact O-CA 3.45Å; A112-G116 PolarHBondContact O-N 3.48Å; A112-F219 HydrophobicContact CB-CD2 3.24Å; A112-F219 HydrophobicContact CB-CE2 3.39Å; A112-F219 HydrophobicContact CB-CG 3.9Å; A112-F219 HydrophobicContact CB-CZ 4.12Å; A112-F219 VanDerWaalsContact N-CE2 3.26Å; A112-L222 HydrophobicContact CB-CD2 4.06Å
113Q89.3Confident88.3Confident90 Ų9041.6 Ų41.642%0.42123%0.229SC..Hα-helixtrans-67.3-45.4178.3-70.9176.2-21.300111.1M109 K110 G116 T117 L222 R226M109-Q113 WeakPolarHBondContact O-CG 3.33Å; M109-Q113 PolarHBondContact O-N 3.48Å; K110-Q113 WeakPolarHBondContact O-CB 3.45Å; K110-Q113 PolarHBondContact O-N 2.93Å; K110-Q113 VanDerWaalsContact O-N 3.07Å; Q113-G116 PolarHBondContact O-N 2.92Å; Q113-T117 PolarHBondContact O-N 2.89Å; Q113-T117 PolarHBondContact O-OG1 3.42Å; Q113-L222 HydrophobicContact CG-CD2 4.34Å; Q113-R226 PolarHBondContact O-NH1 2.92Å
114D89.5Confident89.4Confident62 Ų6241.9 Ų41.933%0.33222%0.223SC..Hα-helixtrans-67.1-44.9-179.5-63.4-21.2000110.8K110 A111 T117 A118K110-D114 PolarHBondContact O-N 3.32Å; A111-D114 PolarHBondContact O-N 2.79Å; D114-T117 PolarHBondContact O-N 3.46Å; D114-A118 PolarHBondContact O-N 2.91Å
115M90.5Very high90.3Very high23 Ų2341.9 Ų41.911%0.11322%0.22CC..Hα-helixtrans-58.8-50.5171.5-78.3-174.7-17500111.4M90 A111 T117 A118 F119 F219 I223M90-M115 HydrophobicContact CE-CB 4.38Å; M90-M115 HydrophobicContact CE-CE 3.67Å; M90-M115 HydrophobicContact CE-CG 3.26Å; M90-M115 HydrophobicContact CE-SD 4.3Å; M90-M115 HydrophobicContact SD-CE 3.44Å; M90-M115 WeakPolarHBondContact SD-CE 3.3Å; M90-M115 HydrophobicContact SD-CG 4.29Å; A111-M115 VanDerWaalsContact O-CB 3.27Å; A111-M115 WeakPolarHBondContact O-CB 3.37Å; A111-M115 VanDerWaalsContact O-CG 3.32Å; A111-M115 WeakPolarHBondContact O-CG 3.21Å; A111-M115 PolarHBondContact O-N 3.22Å; M115-T117 PolarHBondContact O-N 2.93Å; M115-A118 PolarHBondContact O-N 2.86Å; M115-F119 VanDerWaalsContact O-CD2 3.23Å; M115-F119 WeakPolarHBondContact O-CD2 2.9Å; M115-F119 PolarHBondContact O-N 3.42Å; M115-F219 HydrophobicContact SD-CE1 4.14Å; M115-F219 HydrophobicContact SD-CZ 3.76Å; M115-I223 HydrophobicContact CB-CD1 3.83Å; M115-I223 HydrophobicContact CB-CG1 4.2Å; M115-I223 HydrophobicContact SD-CD1 4.2Å
116G93.6Very high91.3Very high0 Ų038 Ų380%020%0.195CC..Hα-helixtrans-61.1-32.3-178.100000112.9A112 Q113 A120 R226A112-G116 WeakPolarHBondContact O-CA 3.45Å; A112-G116 PolarHBondContact O-N 3.48Å; Q113-G116 PolarHBondContact O-N 2.92Å; G116-A120 WeakPolarHBondContact O-CB 3.3Å; G116-A120 PolarHBondContact O-N 3.3Å; G116-A120 VanDerWaalsContact O-N 3.15Å; G116-R226 WeakPolarHBondContact O-CD 3.42Å
117T94Very high92.1Very high58 Ų5831.8 Ų31.836%0.35616%0.163SC..Hα-helixtrans-67.6-48.5171.8-56.50000111.1L86 Q113 D114 M115 F119 A120 E121 R226L86-T117 HydrophobicContact CD1-CG2 4.1Å; Q113-T117 PolarHBondContact O-N 2.89Å; Q113-T117 PolarHBondContact O-OG1 3.42Å; D114-T117 PolarHBondContact O-N 3.46Å; M115-T117 PolarHBondContact O-N 2.93Å; T117-F119 VanDerWaalsContact C-N 3.34Å; T117-F119 PolarHBondContact O-N 2.92Å; T117-A120 PolarHBondContact O-N 2.95Å; T117-E121 WeakPolarHBondContact O-CB 3.43Å; T117-E121 PolarHBondContact O-N 3.15Å; T117-R226 VanDerWaalsContact N-NH1 3.19Å; T117-R226 PolarHBondContact OG1-NH1 2.93Å
118A93.8Very high92.8Very high1 Ų133.1 Ų33.11%0.00817%0.173CC..Hα-helixtrans-60.9-42.8-178.900000112.5L86 D114 M115 Q122L86-A118 HydrophobicContact CB-CB 3.9Å; L86-A118 HydrophobicContact CD1-CB 3.83Å; L86-A118 HydrophobicContact CG-CB 4.41Å; D114-A118 PolarHBondContact O-N 2.91Å; M115-A118 PolarHBondContact O-N 2.86Å; A118-Q122 WeakPolarHBondContact O-CB 3.34Å; A118-Q122 PolarHBondContact O-N 3.48Å
119F95.8Very high93.6Very high1 Ų135 Ų350%0.00418%0.182CC..Hα-helixtrans-67.2-44.6178.3-84.4-106.6000111.8F29 F58 M115 T117 E121 Q122 C123 F149 D150 I223 D227F29-F119 HydrophobicContact CB-CZ 4.46Å; F29-F119 HydrophobicContact CD1-CE2 4.44Å; F29-F119 AromaticContact CD1-CZ 3.95Å; F29-F119 HydrophobicContact CD1-CZ 3.95Å; F29-F119 HydrophobicContact CD2-CE2 4.18Å; F29-F119 HydrophobicContact CD2-CZ 4.29Å; F29-F119 HydrophobicContact CE1-CE2 4.41Å; F29-F119 HydrophobicContact CE1-CZ 4.24Å; F29-F119 HydrophobicContact CE2-CE2 4.14Å; F29-F119 HydrophobicContact CG-CE2 4.32Å; F29-F119 AromaticContact CG-CZ 3.98Å; F29-F119 HydrophobicContact CG-CZ 3.98Å; F29-F119 HydrophobicContact CZ-CE2 4.26Å; F58-F119 HydrophobicContact CE1-CD1 4.39Å; F58-F119 AromaticContact CE1-CD2 3.89Å; F58-F119 HydrophobicContact CE1-CD2 3.89Å; F58-F119 HydrophobicContact CE1-CE2 4.06Å; F58-F119 HydrophobicContact CE1-CG 4.06Å; F58-F119 HydrophobicContact CE1-CZ 4.36Å; F58-F119 AromaticContact CZ-CD1 3.9Å; F58-F119 HydrophobicContact CZ-CD1 3.9Å; F58-F119 HydrophobicContact CZ-CD2 4.23Å; F58-F119 HydrophobicContact CZ-CE1 4.06Å; F58-F119 HydrophobicContact CZ-CE2 4.38Å; F58-F119 AromaticContact CZ-CG 3.98Å; F58-F119 HydrophobicContact CZ-CG 3.98Å; F58-F119 HydrophobicContact CZ-CZ 4.27Å; M115-F119 VanDerWaalsContact O-CD2 3.23Å; M115-F119 WeakPolarHBondContact O-CD2 2.9Å; M115-F119 PolarHBondContact O-N 3.42Å; T117-F119 VanDerWaalsContact C-N 3.34Å; T117-F119 PolarHBondContact O-N 2.92Å; F119-E121 PolarHBondContact O-N 2.86Å; F119-Q122 PolarHBondContact O-N 2.74Å; F119-C123 VanDerWaalsContact O-CB 3.26Å; F119-C123 WeakPolarHBondContact O-CB 3.42Å; F119-C123 PolarHBondContact O-N 3.15Å; F119-F149 HydrophobicContact CE1-CD1 4.12Å; F119-F149 HydrophobicContact CE1-CE1 4.19Å; F119-F149 HydrophobicContact CE2-CE1 4.39Å; F119-F149 AromaticContact CZ-CD1 3.97Å; F119-F149 HydrophobicContact CZ-CD1 3.97Å; F119-F149 AromaticContact CZ-CE1 3.59Å; F119-F149 HydrophobicContact CZ-CE1 3.59Å; F119-D150 HydrophobicContact CD1-CB 4.13Å; F119-D150 HydrophobicContact CE1-CB 3.77Å; F119-I223 HydrophobicContact CB-CG2 3.88Å; F119-I223 HydrophobicContact CD1-CG2 4.06Å; F119-I223 HydrophobicContact CD2-CG2 4.4Å; F119-I223 HydrophobicContact CG-CG2 3.84Å; F119-D227 WeakPolarHBondContact CB-OD1 3.32Å
120A96.4Very high94.2Very high15 Ų1537.3 Ų37.312%0.12420%0.202CC..Hα-helixtrans-62.8-41.2176.600000113.6G116 T117 C123 T124 R226 D227 A230G116-A120 WeakPolarHBondContact O-CB 3.3Å; G116-A120 PolarHBondContact O-N 3.3Å; G116-A120 VanDerWaalsContact O-N 3.15Å; T117-A120 PolarHBondContact O-N 2.95Å; A120-C123 PolarHBondContact O-N 3.37Å; A120-T124 PolarHBondContact O-N 3.21Å; A120-T124 PolarHBondContact O-OG1 2.93Å; A120-R226 HydrophobicContact CB-CB 3.89Å; A120-D227 PolarHBondContact N-OD1 2.94Å; A120-A230 HydrophobicContact CB-CB 3.94Å; A120-A230 VanDerWaalsContact O-CB 3.31Å; A120-A230 WeakPolarHBondContact O-CB 3.26Å
121E96.3Very high94.8Very high56 Ų5633 Ų3326%0.26220%0.196SC..Hα-helixtrans-63.2-48.3176.5-17374.2-169.400110.6P81 V83 T117 F119 C123 T124 K125P81-E121 WeakPolarHBondContact CB-OE1 3.43Å; P81-E121 WeakPolarHBondContact O-CG 3.39Å; P81-E121 VanDerWaalsContact O-OE1 3.08Å; V83-E121 HydrophobicContact CG2-CB 4.15Å; V83-E121 HydrophobicContact CG2-CG 3.84Å; T117-E121 WeakPolarHBondContact O-CB 3.43Å; T117-E121 PolarHBondContact O-N 3.15Å; F119-E121 PolarHBondContact O-N 2.86Å; E121-C123 VanDerWaalsContact C-N 3.3Å; E121-C123 PolarHBondContact O-N 2.96Å; E121-T124 WeakPolarHBondContact O-CB 3.42Å; E121-T124 PolarHBondContact O-N 3.1Å; E121-K125 PolarHBondContact O-N 2.95Å
122Q97.4Very high95.4Very high0 Ų033 Ų330%019%0.194CC..Hα-helixtrans-65.3-35.8176.1-170.660.925.500111.7P56 F58 E78 V83 A118 F119 K125 V126P56-Q122 HydrophobicContact CB-CG 4.07Å; F58-Q122 HydrophobicContact CD1-CB 4.27Å; F58-Q122 HydrophobicContact CD1-CG 4.43Å; F58-Q122 HydrophobicContact CD2-CB 4.48Å; F58-Q122 HydrophobicContact CD2-CG 3.86Å; F58-Q122 HydrophobicContact CE1-CB 3.62Å; F58-Q122 HydrophobicContact CE1-CG 4.07Å; F58-Q122 HydrophobicContact CE2-CB 3.89Å; F58-Q122 HydrophobicContact CE2-CG 3.46Å; F58-Q122 VanDerWaalsContact CE2-CG 3.46Å; F58-Q122 HydrophobicContact CG-CG 4.35Å; F58-Q122 HydrophobicContact CZ-CB 3.42Å; F58-Q122 VanDerWaalsContact CZ-CB 3.42Å; F58-Q122 HydrophobicContact CZ-CG 3.59Å; E78-Q122 PolarHBondContact O-NE2 2.89Å; V83-Q122 HydrophobicContact CG2-CB 4.24Å; A118-Q122 WeakPolarHBondContact O-CB 3.34Å; A118-Q122 PolarHBondContact O-N 3.48Å; F119-Q122 PolarHBondContact O-N 2.74Å; Q122-K125 WeakPolarHBondContact O-CB 3.41Å; Q122-K125 PolarHBondContact O-N 3.06Å; Q122-V126 VanDerWaalsContact O-CG2 3.31Å; Q122-V126 WeakPolarHBondContact O-CG2 3.44Å; Q122-V126 PolarHBondContact O-N 3.31Å
123C98Very high95.9Very high1 Ų134.3 Ų34.31%0.00720%0.201CC..Hα-helixtrans-64.7-44.3176.6-170.30000111.4F119 A120 E121 K125 V126 I127 C152F119-C123 VanDerWaalsContact O-CB 3.26Å; F119-C123 WeakPolarHBondContact O-CB 3.42Å; F119-C123 PolarHBondContact O-N 3.15Å; A120-C123 PolarHBondContact O-N 3.37Å; E121-C123 VanDerWaalsContact C-N 3.3Å; E121-C123 PolarHBondContact O-N 2.96Å; C123-K125 VanDerWaalsContact C-N 3.28Å; C123-K125 PolarHBondContact O-N 3.39Å; C123-V126 PolarHBondContact O-N 2.89Å; C123-I127 VanDerWaalsContact O-CG1 3.31Å; C123-I127 WeakPolarHBondContact O-CG1 3.36Å; C123-I127 PolarHBondContact O-N 3.24Å; C123-C152 WeakPolarHBondContact CA-SG 3.43Å; C123-C152 HydrophobicContact CB-CB 3.59Å; C123-C152 WeakPolarHBondContact CB-SG 3.44Å; C123-C152 WeakPolarHBondContact SG-CB 3.28Å; C123-C152 CovalentContact SG-SG 2.04Å; C123-C152 PolarHBondContact SG-SG 2.87Å
124T97.8Very high96.4Very high45 Ų4536 Ų3628%0.27621%0.209SC..Hα-helixtrans-54.8-46.9172.5-58.40000110.4A120 E121 V126 I127 S128 A230 V234A120-T124 PolarHBondContact O-N 3.21Å; A120-T124 PolarHBondContact O-OG1 2.93Å; E121-T124 WeakPolarHBondContact O-CB 3.42Å; E121-T124 PolarHBondContact O-N 3.1Å; T124-V126 PolarHBondContact O-N 3.38Å; T124-I127 PolarHBondContact O-N 3.4Å; T124-S128 VanDerWaalsContact O-CB 3.26Å; T124-S128 WeakPolarHBondContact O-CB 3.38Å; T124-S128 PolarHBondContact O-N 3.41Å; T124-S128 PolarHBondContact O-OG 3.39Å; T124-A230 WeakPolarHBondContact OG1-CB 3.29Å; T124-V234 HydrophobicContact CG2-CG2 3.96Å
125K97.8Very high96.8Very high56 Ų5638.1 Ų38.124%0.24322%0.215CC..Hα-helixtrans-60.5-43.6177.7176.656175.1149.70112.5V77 E78 E121 Q122 C123 S128 E129V77-K125 HydrophobicContact CG1-CG 3.97Å; E78-K125 WeakPolarHBondContact O-CG 3.25Å; E121-K125 PolarHBondContact O-N 2.95Å; Q122-K125 WeakPolarHBondContact O-CB 3.41Å; Q122-K125 PolarHBondContact O-N 3.06Å; C123-K125 VanDerWaalsContact C-N 3.28Å; C123-K125 PolarHBondContact O-N 3.39Å; K125-S128 PolarHBondContact O-OG 2.86Å; K125-E129 WeakPolarHBondContact CE-OE2 3.22Å; K125-E129 IonicContact NZ-OE2 2.68Å; K125-E129 PolarHBondContact NZ-OE2 3.05Å; K125-E129 PolarHBondContact O-N 3.01Å; K125-E129 VanDerWaalsContact O-N 3.13Å
126V98.3Very high97.1Very high0 Ų037 Ų370%021%0.21CC..Hα-helixtrans-64.8-48.8177.8172.80000112.1Y25 L54 P56 V77 Q122 C123 T124 S128 E129 L132Y25-V126 HydrophobicContact CE2-CG1 4.19Å; L54-V126 HydrophobicContact CD2-CG1 4.46Å; P56-V126 HydrophobicContact CB-CG2 3.62Å; P56-V126 HydrophobicContact CG-CG2 3.55Å; V77-V126 HydrophobicContact CB-CG2 4.14Å; V77-V126 HydrophobicContact CG1-CG2 3.97Å; V77-V126 HydrophobicContact CG2-CG2 4.44Å; Q122-V126 VanDerWaalsContact O-CG2 3.31Å; Q122-V126 WeakPolarHBondContact O-CG2 3.44Å; Q122-V126 PolarHBondContact O-N 3.31Å; C123-V126 PolarHBondContact O-N 2.89Å; T124-V126 PolarHBondContact O-N 3.38Å; V126-S128 VanDerWaalsContact C-N 3.3Å; V126-S128 PolarHBondContact O-N 3.27Å; V126-E129 WeakPolarHBondContact O-CB 3.44Å; V126-E129 PolarHBondContact O-N 3.23Å; V126-L132 HydrophobicContact CG1-CD2 4.23Å; V126-L132 WeakPolarHBondContact O-CD2 3.41Å
127I98.3Very high97.3Very high5 Ų543 Ų433%0.02624%0.235CC..Hα-helixtrans-70-30-176.3-61.7-62.7000111.6C123 T124 L133 L156 A231 V234 V235C123-I127 VanDerWaalsContact O-CG1 3.31Å; C123-I127 WeakPolarHBondContact O-CG1 3.36Å; C123-I127 PolarHBondContact O-N 3.24Å; T124-I127 PolarHBondContact O-N 3.4Å; I127-L133 HydrophobicContact CG2-CD1 4.34Å; I127-L156 HydrophobicContact CD1-CB 4.25Å; I127-L156 HydrophobicContact CD1-CD1 4.22Å; I127-A231 HydrophobicContact CG1-CB 3.92Å; I127-V234 HydrophobicContact CB-CB 4.49Å; I127-V234 HydrophobicContact CB-CG1 4.46Å; I127-V234 HydrophobicContact CG2-CB 3.79Å; I127-V234 HydrophobicContact CG2-CG1 3.77Å; I127-V235 HydrophobicContact CG2-CB 3.9Å; I127-V235 HydrophobicContact CG2-CG1 3.5Å; I127-V235 VanDerWaalsContact CG2-CG1 3.5Å
128S97.5Very high97.5Very high60 Ų6043.6 Ų43.642%0.4225%0.246SC..THydrogen-bonded Turntrans-88.9-0.1176.863.40000114.5T124 K125 V126 P130T124-S128 VanDerWaalsContact O-CB 3.26Å; T124-S128 WeakPolarHBondContact O-CB 3.38Å; T124-S128 PolarHBondContact O-N 3.41Å; T124-S128 PolarHBondContact O-OG 3.39Å; K125-S128 PolarHBondContact O-OG 2.86Å; V126-S128 VanDerWaalsContact C-N 3.3Å; V126-S128 PolarHBondContact O-N 3.27Å; S128-P130 WeakPolarHBondContact O-CD 3.41Å
129E98.1Very high97.7Very high56 Ų5646.5 Ų46.526%0.26226%0.26SS..SBendtrans-61.7121.2-178.4-173.963.3-151.700110.6V77 K125 V126 G131 L132V77-E129 HydrophobicContact CG1-CB 4.38Å; V77-E129 HydrophobicContact CG1-CG 4.4Å; V77-E129 HydrophobicContact CG2-CB 4.44Å; V77-E129 HydrophobicContact CG2-CG 4.22Å; K125-E129 WeakPolarHBondContact CE-OE2 3.22Å; K125-E129 IonicContact NZ-OE2 2.68Å; K125-E129 PolarHBondContact NZ-OE2 3.05Å; K125-E129 PolarHBondContact O-N 3.01Å; K125-E129 VanDerWaalsContact O-N 3.13Å; V126-E129 WeakPolarHBondContact O-CB 3.44Å; V126-E129 PolarHBondContact O-N 3.23Å; E129-G131 PolarHBondContact O-N 3.42Å; E129-L132 HydrophobicContact CB-CB 3.87Å; E129-L132 HydrophobicContact CB-CD2 3.89Å; E129-L132 HydrophobicContact CG-CB 4.08Å; E129-L132 HydrophobicContact CG-CD2 4.29Å; E129-L132 WeakPolarHBondContact O-CB 3.42Å; E129-L132 PolarHBondContact O-N 2.9Å; E129-L132 VanDerWaalsContact O-N 3.12Å
130P97.7Very high97.7Very high112 Ų11252.6 Ų52.673%0.72729%0.293SS*.THydrogen-bonded Turntrans-56.6123-171.1-28.435.7000113.8S128 L132S128-P130 WeakPolarHBondContact O-CD 3.41Å; P130-L132 PolarHBondContact O-N 3.02Å
131G97.7Very high97.8Very high43 Ų4352.5 Ų52.544%0.44329%0.289SS..THydrogen-bonded Turntrans74.1-1.2176.100000115.2E129 E134 K135E129-G131 PolarHBondContact O-N 3.42Å; G131-E134 VanDerWaalsContact C-OE2 3.27Å; G131-E134 WeakPolarHBondContact CA-OE2 3.24Å; G131-K135 VanDerWaalsContact O-CB 3.25Å; G131-K135 WeakPolarHBondContact O-CB 3.43Å; G131-K135 PolarHBondContact O-N 2.8Å
132L98.6Very high97.9Very high10 Ų1052.6 Ų52.65%0.05229%0.291CS..Hα-helixtrans-66.4-49.7-176.5178.862.7000111.4L54 I75 V77 V126 E129 P130 E134 K135 L136L54-L132 HydrophobicContact CD1-CD1 4.31Å; L54-L132 HydrophobicContact CD1-CD2 4.26Å; L54-L132 HydrophobicContact CD2-CD2 4.3Å; I75-L132 HydrophobicContact CG2-CD1 3.9Å; V77-L132 HydrophobicContact CG2-CD2 3.72Å; V126-L132 HydrophobicContact CG1-CD2 4.23Å; V126-L132 WeakPolarHBondContact O-CD2 3.41Å; E129-L132 HydrophobicContact CB-CB 3.87Å; E129-L132 HydrophobicContact CB-CD2 3.89Å; E129-L132 HydrophobicContact CG-CB 4.08Å; E129-L132 HydrophobicContact CG-CD2 4.29Å; E129-L132 WeakPolarHBondContact O-CB 3.42Å; E129-L132 PolarHBondContact O-N 2.9Å; E129-L132 VanDerWaalsContact O-N 3.12Å; P130-L132 PolarHBondContact O-N 3.02Å; L132-E134 VanDerWaalsContact C-N 3.35Å; L132-E134 PolarHBondContact O-N 2.85Å; L132-K135 PolarHBondContact O-N 2.78Å; L132-L136 HydrophobicContact CD1-CD1 3.9Å; L132-L136 HydrophobicContact CD1-CG 4.03Å; L132-L136 HydrophobicContact CG-CD1 3.9Å; L132-L136 HydrophobicContact CG-CG 4.39Å; L132-L136 WeakPolarHBondContact O-CB 3.49Å; L132-L136 VanDerWaalsContact O-CG 3.27Å; L132-L136 WeakPolarHBondContact O-CG 3.38Å; L132-L136 PolarHBondContact O-N 3.44Å
133L98.3Very high97.9Very high26 Ų2652.6 Ų52.614%0.13629%0.291CS..Hα-helixtrans-63.1-42.7-178.1-62.7-176.4000111.4I127 L136 K137 L156 A159 I160 V235I127-L133 HydrophobicContact CG2-CD1 4.34Å; L133-L136 PolarHBondContact O-N 3.42Å; L133-K137 WeakPolarHBondContact O-CB 3.46Å; L133-K137 PolarHBondContact O-N 3Å; L133-L156 HydrophobicContact CD2-CD1 3.38Å; L133-A159 HydrophobicContact CD1-CB 4.29Å; L133-A159 HydrophobicContact CD2-CB 4.23Å; L133-I160 HydrophobicContact CD2-CG2 4.21Å; L133-V235 HydrophobicContact CD1-CB 4.49Å; L133-V235 HydrophobicContact CD1-CG2 4.13Å
134E98Very high98Very high127 Ų12752.6 Ų52.659%0.59329%0.291SS*.Hα-helixtrans-61.9-45.3177-65.176.8-171.600111G131 L132 K137 A138G131-E134 VanDerWaalsContact C-OE2 3.27Å; G131-E134 WeakPolarHBondContact CA-OE2 3.24Å; L132-E134 VanDerWaalsContact C-N 3.35Å; L132-E134 PolarHBondContact O-N 2.85Å; E134-K137 PolarHBondContact O-N 2.93Å; E134-A138 WeakPolarHBondContact O-CB 3.2Å; E134-A138 PolarHBondContact O-N 3.38Å
135K98.2Very high98Very high105 Ų10550.4 Ų50.446%0.45728%0.278SS..Hα-helixtrans-59.8-53.2175.8-179.2-179.3177.1-176.70110.7G131 L132 K137 A138 E139G131-K135 VanDerWaalsContact O-CB 3.25Å; G131-K135 WeakPolarHBondContact O-CB 3.43Å; G131-K135 PolarHBondContact O-N 2.8Å; L132-K135 PolarHBondContact O-N 2.78Å; K135-K137 VanDerWaalsContact C-N 3.3Å; K135-K137 PolarHBondContact O-N 3.36Å; K135-A138 WeakPolarHBondContact O-CB 3.17Å; K135-A138 PolarHBondContact O-N 2.99Å; K135-A138 VanDerWaalsContact O-N 3.13Å; K135-E139 WeakPolarHBondContact O-CG 3.43Å; K135-E139 PolarHBondContact O-N 2.93Å; K135-E139 VanDerWaalsContact O-N 3.16Å
136L98.5Very high98.1Very high1 Ų147.8 Ų47.81%0.00527%0.267CS..Hα-helixtrans-62.1-37.2-178.1-68174.8000112.5L23 L54 I75 L132 L133 E139 Y141 L156 I160L23-L136 HydrophobicContact CD1-CD2 4.02Å; L23-L136 HydrophobicContact CD2-CD2 4.3Å; L54-L136 HydrophobicContact CD2-CD1 4.02Å; I75-L136 HydrophobicContact CD1-CD2 3.97Å; L132-L136 HydrophobicContact CD1-CD1 3.9Å; L132-L136 HydrophobicContact CD1-CG 4.03Å; L132-L136 HydrophobicContact CG-CD1 3.9Å; L132-L136 HydrophobicContact CG-CG 4.39Å; L132-L136 WeakPolarHBondContact O-CB 3.49Å; L132-L136 VanDerWaalsContact O-CG 3.27Å; L132-L136 WeakPolarHBondContact O-CG 3.38Å; L132-L136 PolarHBondContact O-N 3.44Å; L133-L136 PolarHBondContact O-N 3.42Å; L136-E139 PolarHBondContact O-N 2.77Å; L136-Y141 HydrophobicContact CD2-CE2 4.02Å; L136-L156 HydrophobicContact CD1-CD1 3.88Å; L136-L156 HydrophobicContact CD1-CD2 4.12Å; L136-L156 HydrophobicContact CD1-CG 4.38Å; L136-I160 HydrophobicContact CB-CD1 4.35Å; L136-I160 HydrophobicContact CB-CG2 3.94Å
137K97.7Very high98Very high124 Ų12448.1 Ų48.154%0.53927%0.268SS..Hα-helixtrans-66.1-40.6174.6-172.1173.8-1761730111.9L133 E134 K135 E139 N140 I160L133-K137 WeakPolarHBondContact O-CB 3.46Å; L133-K137 PolarHBondContact O-N 3Å; E134-K137 PolarHBondContact O-N 2.93Å; K135-K137 VanDerWaalsContact C-N 3.3Å; K135-K137 PolarHBondContact O-N 3.36Å; K137-E139 PolarHBondContact O-N 2.89Å; K137-N140 PolarHBondContact O-N 2.89Å; K137-I160 HydrophobicContact CB-CB 4.41Å
138A97.9Very high97.9Very high71 Ų7147.9 Ų47.959%0.58727%0.267SS*.Hα-helixtrans-65.9-25.7177.800000113.2E134 K135 N140E134-A138 WeakPolarHBondContact O-CB 3.2Å; E134-A138 PolarHBondContact O-N 3.38Å; K135-A138 WeakPolarHBondContact O-CB 3.17Å; K135-A138 PolarHBondContact O-N 2.99Å; K135-A138 VanDerWaalsContact O-N 3.13Å; A138-N140 VanDerWaalsContact C-N 3.26Å; A138-N140 PolarHBondContact O-N 3.45Å; A138-N140 PolarHBondContact O-ND2 3.19Å
139E97.1Very high97.8Very high63 Ų6345.9 Ų45.929%0.29425%0.251SS..THydrogen-bonded Turntrans-68-22.1178.7-67.3-64.3156.500113.4K21 K135 L136 K137 Y141K21-E139 WeakPolarHBondContact CD-O 3.42Å; K21-E139 WeakPolarHBondContact CE-O 2.99Å; K21-E139 WeakPolarHBondContact CE-OE2 3.09Å; K21-E139 PolarHBondContact NZ-O 3Å; K21-E139 IonicContact NZ-OE2 3.19Å; K21-E139 PolarHBondContact NZ-OE2 3.31Å; K135-E139 WeakPolarHBondContact O-CG 3.43Å; K135-E139 PolarHBondContact O-N 2.93Å; K135-E139 VanDerWaalsContact O-N 3.16Å; L136-E139 PolarHBondContact O-N 2.77Å; K137-E139 PolarHBondContact O-N 2.89Å; E139-Y141 HydrophobicContact CB-CD2 3.83Å; E139-Y141 HydrophobicContact CB-CE1 4.38Å; E139-Y141 HydrophobicContact CB-CE2 3.36Å; E139-Y141 HydrophobicContact CG-CE2 3.87Å
140N96Very high97.6Very high129 Ų12943.5 Ų43.569%0.6924%0.24SC*.  trans5056.8-179.7-64.5-76000113.4K137 A138K137-N140 PolarHBondContact O-N 2.89Å; A138-N140 VanDerWaalsContact C-N 3.26Å; A138-N140 PolarHBondContact O-N 3.45Å; A138-N140 PolarHBondContact O-ND2 3.19Å
141Y98.3Very high97.6Very high13 Ų1338.3 Ų38.35%0.05121%0.206CC..  trans-60.4139.3177.9-66.3-80.3000112.5K21 L23 T52 L136 E139K21-Y141 HydrophobicContact CB-CD1 4.36Å; K21-Y141 HydrophobicContact CD-CD1 4.18Å; K21-Y141 HydrophobicContact CD-CE1 4.37Å; K21-Y141 HydrophobicContact CG-CD1 3.7Å; K21-Y141 HydrophobicContact CG-CE1 3.95Å; L23-Y141 HydrophobicContact CB-CD1 3.69Å; L23-Y141 HydrophobicContact CB-CD2 3.81Å; L23-Y141 HydrophobicContact CB-CE1 3.88Å; L23-Y141 HydrophobicContact CB-CE2 3.97Å; L23-Y141 HydrophobicContact CB-CG 3.67Å; L23-Y141 HydrophobicContact CD1-CE2 4.19Å; L23-Y141 HydrophobicContact CD2-CD2 4.15Å; L23-Y141 HydrophobicContact CD2-CE2 4.12Å; L23-Y141 HydrophobicContact CG-CD2 4.47Å; L23-Y141 HydrophobicContact CG-CE2 4.32Å; T52-Y141 VanDerWaalsContact CB-OH 3.23Å; T52-Y141 WeakPolarHBondContact CB-OH 3.43Å; T52-Y141 WeakPolarHBondContact CG2-OH 3.36Å; T52-Y141 WeakPolarHBondContact OG1-CE1 3.37Å; T52-Y141 PolarHBondContact OG1-OH 3.09Å; L136-Y141 HydrophobicContact CD2-CE2 4.02Å; E139-Y141 HydrophobicContact CB-CD2 3.83Å; E139-Y141 HydrophobicContact CB-CE1 4.38Å; E139-Y141 HydrophobicContact CB-CE2 3.36Å; E139-Y141 HydrophobicContact CG-CE2 3.87Å
142D98.1Very high97.6Very high58 Ų5836.3 Ų36.331%0.3119%0.185SC..SBendtrans-73.2-32.2176.7-63-59.8000111.8Y20 K21 A470Y20-D142 WeakPolarHBondContact CA-OD2 3.47Å; Y20-D142 HydrophobicContact CD1-CB 4.12Å; K21-D142 PolarHBondContact N-OD2 3.08Å; K21-D142 PolarHBondContact O-N 3.45Å; D142-A470 HydrophobicContact CB-CB 4.27Å
143L98.7Very high97.6Very high0 Ų035.8 Ų35.80%018%0.182CC..EExtended strand (participates in β ladder)trans-150.9149-178.6-168.476.7000110.4I22 L23 I145 A164 V166 V466 A469 A470I22-L143 WeakPolarHBondContact CA-O 3.39Å; L23-L143 PolarHBondContact N-O 3.38Å; L143-I145 HydrophobicContact CD2-CG1 4.42Å; L143-A164 HydrophobicContact CD1-CB 3.82Å; L143-V166 HydrophobicContact CD2-CG1 4.3Å; L143-V166 HydrophobicContact CD2-CG2 4.09Å; L143-V466 HydrophobicContact CD2-CB 4.47Å; L143-V466 HydrophobicContact CD2-CG1 3.7Å; L143-A469 HydrophobicContact CD1-CB 3.76Å; L143-A469 HydrophobicContact CD2-CB 4.13Å; L143-A470 HydrophobicContact CB-CB 3.94Å; L143-A470 HydrophobicContact CD2-CB 4.43Å
144A98.9Very high97.6Very high0 Ų034.6 Ų34.60%018%0.176CC..EExtended strand (participates in β ladder)trans-117.1155163.900000113.7L23 F157 I162 A164 H165 V166L23-A144 HydrophobicContact CB-CB 4.2Å; L23-A144 CarbonylContact O-C 3.57Å; L23-A144 WeakPolarHBondContact O-CA 3.26Å; A144-F157 HydrophobicContact CB-CD1 3.73Å; A144-F157 HydrophobicContact CB-CD2 4.18Å; A144-F157 HydrophobicContact CB-CE1 3.33Å; A144-F157 HydrophobicContact CB-CE2 3.8Å; A144-F157 HydrophobicContact CB-CG 4.16Å; A144-F157 HydrophobicContact CB-CZ 3.36Å; A144-I162 HydrophobicContact CB-CD1 4.05Å; A144-I162 HydrophobicContact CB-CG1 3.76Å; A144-A164 PolarHBondContact N-O 3.23Å; A144-H165 HydrophobicContact CB-CB 4.45Å; A144-H165 CarbonylContact O-C 3.54Å; A144-H165 WeakPolarHBondContact O-CA 3.31Å; A144-H165 WeakPolarHBondContact O-CB 3.46Å; A144-V166 PolarHBondContact O-N 3.43Å
145I98.9Very high97.6Very high0 Ų028.7 Ų28.70%015%0.149CC..EExtended strand (participates in β ladder)trans-131132.3-178.3-51.7-169.2000108.2I22 L23 L24 Y25 L44 L143 V166 I168 V466I22-I145 HydrophobicContact CG2-CD1 3.75Å; I22-I145 HydrophobicContact CG2-CG1 3.83Å; L23-I145 PolarHBondContact O-N 3.47Å; L24-I145 CarbonylContact C-O 3.38Å; L24-I145 WeakPolarHBondContact CA-O 3.45Å; L24-I145 HydrophobicContact CB-CB 4.36Å; L24-I145 HydrophobicContact CD1-CB 4.2Å; L24-I145 HydrophobicContact CD1-CD1 4.49Å; L24-I145 HydrophobicContact CD1-CG2 4.07Å; L24-I145 HydrophobicContact CG-CB 4.03Å; L24-I145 HydrophobicContact CG-CG2 4.19Å; Y25-I145 PolarHBondContact N-O 2.99Å; L44-I145 HydrophobicContact CD1-CD1 3.58Å; L143-I145 HydrophobicContact CD2-CG1 4.42Å; I145-V166 WeakPolarHBondContact CA-O 3.43Å; I145-V166 HydrophobicContact CB-CG2 4.22Å; I145-V166 HydrophobicContact CD1-CG2 3.95Å; I145-V166 HydrophobicContact CG1-CG2 3.6Å; I145-V166 HydrophobicContact CG2-CG2 4.12Å; I145-I168 HydrophobicContact CG2-CD1 3.55Å; I145-I168 HydrophobicContact CG2-CG1 3.77Å; I145-V466 HydrophobicContact CD1-CG1 4.2Å; I145-V466 HydrophobicContact CD1-CG2 4.13Å
146T98.6Very high97.6Very high1 Ų123.7 Ų23.71%0.00613%0.128CC..EExtended strand (participates in β ladder)trans-144.3163.4170-165.70000110.6Y25 Y154 F157 V166 A167 I168Y25-T146 WeakPolarHBondContact CD1-OG1 3.46Å; T146-Y154 HydrophobicContact CG2-CD1 4.16Å; T146-Y154 HydrophobicContact CG2-CD2 4.35Å; T146-Y154 HydrophobicContact CG2-CE1 3.65Å; T146-Y154 HydrophobicContact CG2-CE2 3.85Å; T146-Y154 HydrophobicContact CG2-CG 4.47Å; T146-Y154 VanDerWaalsContact CG2-CZ 3.43Å; T146-F157 HydrophobicContact CG2-CE2 3.68Å; T146-F157 HydrophobicContact CG2-CZ 3.97Å; T146-V166 PolarHBondContact N-O 2.93Å; T146-A167 WeakPolarHBondContact O-CA 2.98Å; T146-I168 PolarHBondContact O-N 3.26Å
147E98Very high97.6Very high7 Ų723.8 Ų23.83%0.03313%0.128CC..  trans-92.8130.3165.2178.7177.7-145.300110.1H33 L37 F149 D150 I168 T170 F174H33-E147 IonicContact CE1-OE1 2.58Å; H33-E147 IonicContact CE1-OE2 3.28Å; H33-E147 IonicContact CG-OE2 2.83Å; H33-E147 IonicContact ND1-OE1 3.45Å; H33-E147 PolarHBondContact ND1-OE1 3.41Å; H33-E147 IonicContact ND1-OE2 2.89Å; H33-E147 PolarHBondContact ND1-OE2 2.83Å; L37-E147 HydrophobicContact CD1-CB 3.99Å; L37-E147 HydrophobicContact CD2-CB 4.4Å; E147-F149 HydrophobicContact CG-CB 3.65Å; E147-F149 PolarHBondContact O-N 2.92Å; E147-D150 PolarHBondContact O-N 3.26Å; E147-I168 VanDerWaalsContact CA-O 3.24Å; E147-I168 WeakPolarHBondContact CA-O 3.38Å; E147-I168 VanDerWaalsContact CB-O 3.28Å; E147-I168 WeakPolarHBondContact CB-O 3.41Å; E147-I168 VanDerWaalsContact CG-O 3.29Å; E147-I168 WeakPolarHBondContact CG-O 3.46Å; E147-T170 VanDerWaalsContact OE1-CB 3.26Å; E147-T170 WeakPolarHBondContact OE1-CB 3.43Å; E147-T170 VanDerWaalsContact OE1-CG2 3.31Å; E147-T170 WeakPolarHBondContact OE1-CG2 3.42Å; E147-T170 PolarHBondContact OE1-N 3.15Å; E147-T170 PolarHBondContact OE1-OG1 2.95Å; E147-F174 HydrophobicContact CG-CE2 4.12Å; E147-F174 WeakPolarHBondContact OE1-CZ 3.32Å
148P96.2Very high97.6Very high0 Ų019.5 Ų19.50%011%0.11CC..THydrogen-bonded Turntrans-7316.4177.130.3-34.9000114.9Y154 A167 L169 F174 H176 V177 L245P148-Y154 HydrophobicContact CB-CE2 3.92Å; P148-A167 HydrophobicContact CG-CB 4.42Å; P148-L169 HydrophobicContact CG-CD1 3.61Å; P148-L169 HydrophobicContact CG-CG 4.09Å; P148-F174 HydrophobicContact CG-CD2 4.27Å; P148-H176 PolarHBondContact O-NE2 3.45Å; P148-V177 HydrophobicContact CB-CG2 3.61Å; P148-V177 HydrophobicContact CG-CG2 3.39Å; P148-L245 HydrophobicContact CB-CD1 4.25Å; P148-L245 HydrophobicContact CB-CD2 4.29Å
149F93.5Very high97.6Very high18 Ų1817.3 Ų17.38%0.0799%0.091CC..THydrogen-bonded Turntrans-79.7-39.2166.9-173.7-92.5000110.3F29 H33 F119 E147 F174 F220F29-F149 AromaticContact CD1-CE1 3.7Å; F29-F149 HydrophobicContact CD1-CE1 3.7Å; F29-F149 HydrophobicContact CD1-CZ 4.44Å; F29-F149 AromaticContact CE1-CE1 3.53Å; F29-F149 HydrophobicContact CE1-CE1 3.53Å; F29-F149 AromaticContact CE1-CZ 3.85Å; F29-F149 HydrophobicContact CE1-CZ 3.85Å; H33-F149 AromaticContact CE1-CD2 3.86Å; H33-F149 AromaticContact CE1-CG 3.91Å; F119-F149 HydrophobicContact CE1-CD1 4.12Å; F119-F149 HydrophobicContact CE1-CE1 4.19Å; F119-F149 HydrophobicContact CE2-CE1 4.39Å; F119-F149 AromaticContact CZ-CD1 3.97Å; F119-F149 HydrophobicContact CZ-CD1 3.97Å; F119-F149 AromaticContact CZ-CE1 3.59Å; F119-F149 HydrophobicContact CZ-CE1 3.59Å; E147-F149 HydrophobicContact CG-CB 3.65Å; E147-F149 PolarHBondContact O-N 2.92Å; F149-F174 HydrophobicContact CB-CE2 4.1Å; F149-F174 HydrophobicContact CB-CZ 4.12Å; F149-F174 HydrophobicContact CD2-CE1 4.14Å; F149-F174 AromaticContact CD2-CZ 3.94Å; F149-F174 HydrophobicContact CD2-CZ 3.94Å; F149-F174 HydrophobicContact CG-CZ 4.47Å; F149-F220 HydrophobicContact CD2-CD1 4.32Å; F149-F220 AromaticContact CD2-CE1 3.94Å; F149-F220 HydrophobicContact CD2-CE1 3.94Å; F149-F220 HydrophobicContact CE2-CD1 4.22Å; F149-F220 AromaticContact CE2-CE1 3.49Å; F149-F220 HydrophobicContact CE2-CE1 3.49Å; F149-F220 VanDerWaalsContact CE2-CE1 3.49Å; F149-F220 HydrophobicContact CE2-CZ 4.3Å; F149-F220 HydrophobicContact CZ-CE1 4.41Å
150D94.9Very high97.6Very high5 Ų514.8 Ų14.83%0.0278%0.08CC..SBendtrans-106.3105.4167.9-173.1-23.3000108.7Y25 N27 F119 E147 C152Y25-D150 HydrophobicContact CE1-CB 4.31Å; Y25-D150 WeakPolarHBondContact CE1-OD2 3.39Å; N27-D150 VanDerWaalsContact ND2-CB 3.33Å; N27-D150 WeakPolarHBondContact ND2-CB 3.39Å; N27-D150 PolarHBondContact ND2-OD2 3.29Å; F119-D150 HydrophobicContact CD1-CB 4.13Å; F119-D150 HydrophobicContact CE1-CB 3.77Å; E147-D150 PolarHBondContact O-N 3.26Å; D150-C152 VanDerWaalsContact C-N 3.29Å; D150-C152 PolarHBondContact O-N 2.89Å; D150-C152 WeakPolarHBondContact OD1-CB 3.45Å; D150-C152 PolarHBondContact OD1-N 2.87Å
151T96.7Very high97.6Very high4 Ų414.6 Ų14.63%0.0258%0.079CC..THydrogen-bonded Turntrans-86.6-5.3-174.675.70000112.9G153 Y154 A155 G224 D227 W241T151-G153 PolarHBondContact O-N 3.45Å; T151-Y154 WeakPolarHBondContact O-CB 3.06Å; T151-Y154 PolarHBondContact O-N 3Å; T151-A155 PolarHBondContact O-N 3.09Å; T151-G224 WeakPolarHBondContact OG1-CA 3.49Å; T151-G224 PolarHBondContact OG1-O 3.43Å; T151-D227 PolarHBondContact N-OD2 3.26Å; T151-D227 VanDerWaalsContact OG1-CB 3.27Å; T151-D227 WeakPolarHBondContact OG1-CB 3.22Å; T151-D227 PolarHBondContact OG1-OD2 2.85Å; T151-W241 HydrophobicContact CG2-CB 4.21Å; T151-W241 HydrophobicContact CG2-CD2 4.13Å; T151-W241 HydrophobicContact CG2-CE3 4.5Å; T151-W241 HydrophobicContact CG2-CG 3.99Å
152C98.1Very high97.6Very high0 Ų015 Ų150%08%0.081CC..Hα-helixtrans-57.3-30.3173.1-168.30000111.8Y25 C123 D150 Y154 A155 L156 D227Y25-C152 WeakPolarHBondContact OH-CB 3.41Å; C123-C152 WeakPolarHBondContact CA-SG 3.43Å; C123-C152 HydrophobicContact CB-CB 3.59Å; C123-C152 WeakPolarHBondContact CB-SG 3.44Å; C123-C152 WeakPolarHBondContact SG-CB 3.28Å; C123-C152 CovalentContact SG-SG 2.04Å; C123-C152 PolarHBondContact SG-SG 2.87Å; D150-C152 VanDerWaalsContact C-N 3.29Å; D150-C152 PolarHBondContact O-N 2.89Å; D150-C152 WeakPolarHBondContact OD1-CB 3.45Å; D150-C152 PolarHBondContact OD1-N 2.87Å; C152-Y154 PolarHBondContact O-N 3.5Å; C152-A155 WeakPolarHBondContact O-CB 3.37Å; C152-A155 PolarHBondContact O-N 3.25Å; C152-A155 VanDerWaalsContact O-N 3.1Å; C152-L156 PolarHBondContact O-N 3.27Å; C152-D227 HydrophobicContact CB-CB 4.43Å; C152-D227 PolarHBondContact N-OD2 3.39Å
153G98.2Very high97.5Very high0 Ų019.4 Ų19.40%09%0.094CC..Hα-helixtrans-52.9-38.1170.700000113.1T151 L156 F157T151-G153 PolarHBondContact O-N 3.45Å; G153-L156 WeakPolarHBondContact O-CB 3.4Å; G153-L156 PolarHBondContact O-N 3.45Å; G153-F157 WeakPolarHBondContact O-CB 3.38Å; G153-F157 WeakPolarHBondContact O-CD1 3.4Å; G153-F157 WeakPolarHBondContact O-CE1 3.23Å; G153-F157 WeakPolarHBondContact O-CG 3.27Å; G153-F157 PolarHBondContact O-N 2.94Å
154Y98.4Very high97.5Very high0 Ų019.4 Ų19.40%09%0.094CC..Hα-helixtrans-73.2-36.6176.6-61.3-67.2000112.9T146 P148 T151 C152 L156 F157 E158 H165 W241 I244 L245T146-Y154 HydrophobicContact CG2-CD1 4.16Å; T146-Y154 HydrophobicContact CG2-CD2 4.35Å; T146-Y154 HydrophobicContact CG2-CE1 3.65Å; T146-Y154 HydrophobicContact CG2-CE2 3.85Å; T146-Y154 HydrophobicContact CG2-CG 4.47Å; T146-Y154 VanDerWaalsContact CG2-CZ 3.43Å; P148-Y154 HydrophobicContact CB-CE2 3.92Å; T151-Y154 WeakPolarHBondContact O-CB 3.06Å; T151-Y154 PolarHBondContact O-N 3Å; C152-Y154 PolarHBondContact O-N 3.5Å; Y154-L156 VanDerWaalsContact C-N 3.31Å; Y154-F157 HydrophobicContact CD1-CD2 4.14Å; Y154-F157 HydrophobicContact CD1-CE2 4.48Å; Y154-F157 PolarHBondContact O-N 3.02Å; Y154-E158 PolarHBondContact O-N 2.64Å; Y154-H165 AromaticContact CE1-CD2 3.77Å; Y154-H165 AromaticContact CE1-NE2 3.79Å; Y154-W241 HydrophobicContact CD2-CB 3.84Å; Y154-W241 HydrophobicContact CG-CB 4.27Å; Y154-I244 HydrophobicContact CD1-CB 4.29Å; Y154-I244 HydrophobicContact CD1-CG2 3.67Å; Y154-I244 HydrophobicContact CG-CG2 4.29Å; Y154-I244 WeakPolarHBondContact O-CD1 3.46Å; Y154-L245 HydrophobicContact CE1-CB 4.28Å; Y154-L245 HydrophobicContact CE1-CD1 4.37Å; Y154-L245 HydrophobicContact CE2-CB 4.37Å; Y154-L245 HydrophobicContact CE2-CD1 4.48Å; Y154-L245 VanDerWaalsContact OH-CD1 3.28Å; Y154-L245 WeakPolarHBondContact OH-CD1 3.26Å
155A98.4Very high97.5Very high4 Ų419.6 Ų19.63%0.03310%0.095CC..Hα-helixtrans-62.6-41.1172.900000111.4T151 C152 E158 A159 A231 I237T151-A155 PolarHBondContact O-N 3.09Å; C152-A155 WeakPolarHBondContact O-CB 3.37Å; C152-A155 PolarHBondContact O-N 3.25Å; C152-A155 VanDerWaalsContact O-N 3.1Å; A155-E158 PolarHBondContact O-N 3.27Å; A155-A159 WeakPolarHBondContact O-CB 3.35Å; A155-A159 PolarHBondContact O-N 2.92Å; A155-A231 HydrophobicContact CB-CB 3.47Å; A155-A231 VanDerWaalsContact CB-CB 3.47Å; A155-I237 HydrophobicContact CB-CD1 3.65Å
156L98.4Very high97.5Very high0 Ų019.6 Ų19.60%010%0.095CC..Hα-helixtrans-60.9-46.6173-178.474.3000111.7Y25 L54 I127 L133 L136 C152 G153 Y154 E158 A159 I160Y25-L156 HydrophobicContact CD2-CD2 3.62Å; Y25-L156 HydrophobicContact CE2-CD2 4.07Å; L54-L156 HydrophobicContact CD2-CD2 3.47Å; L54-L156 VanDerWaalsContact CD2-CD2 3.47Å; I127-L156 HydrophobicContact CD1-CB 4.25Å; I127-L156 HydrophobicContact CD1-CD1 4.22Å; L133-L156 HydrophobicContact CD2-CD1 3.38Å; L136-L156 HydrophobicContact CD1-CD1 3.88Å; L136-L156 HydrophobicContact CD1-CD2 4.12Å; L136-L156 HydrophobicContact CD1-CG 4.38Å; C152-L156 PolarHBondContact O-N 3.27Å; G153-L156 WeakPolarHBondContact O-CB 3.4Å; G153-L156 PolarHBondContact O-N 3.45Å; Y154-L156 VanDerWaalsContact C-N 3.31Å; L156-E158 VanDerWaalsContact C-N 3.28Å; L156-E158 PolarHBondContact O-N 3.27Å; L156-A159 PolarHBondContact O-N 3.36Å; L156-A159 VanDerWaalsContact O-N 3.15Å; L156-I160 HydrophobicContact CD1-CG2 4.43Å; L156-I160 WeakPolarHBondContact O-CG1 3.39Å; L156-I160 PolarHBondContact O-N 3.48Å
157F98.2Very high97.5Very high3 Ų319.5 Ų19.51%0.0139%0.094CC..Hα-helixtrans-59.4-39.1179.3-70.10.2000112.3A144 T146 G153 Y154 N161 I162 H165A144-F157 HydrophobicContact CB-CD1 3.73Å; A144-F157 HydrophobicContact CB-CD2 4.18Å; A144-F157 HydrophobicContact CB-CE1 3.33Å; A144-F157 HydrophobicContact CB-CE2 3.8Å; A144-F157 HydrophobicContact CB-CG 4.16Å; A144-F157 HydrophobicContact CB-CZ 3.36Å; T146-F157 HydrophobicContact CG2-CE2 3.68Å; T146-F157 HydrophobicContact CG2-CZ 3.97Å; G153-F157 WeakPolarHBondContact O-CB 3.38Å; G153-F157 WeakPolarHBondContact O-CD1 3.4Å; G153-F157 WeakPolarHBondContact O-CE1 3.23Å; G153-F157 WeakPolarHBondContact O-CG 3.27Å; G153-F157 PolarHBondContact O-N 2.94Å; Y154-F157 HydrophobicContact CD1-CD2 4.14Å; Y154-F157 HydrophobicContact CD1-CE2 4.48Å; Y154-F157 PolarHBondContact O-N 3.02Å; F157-N161 PolarHBondContact O-N 2.83Å; F157-N161 VanDerWaalsContact O-N 3.17Å; F157-I162 HydrophobicContact CB-CB 4.45Å; F157-I162 HydrophobicContact CB-CG2 3.57Å; F157-I162 HydrophobicContact CD2-CG2 4.4Å; F157-I162 HydrophobicContact CG-CG2 3.97Å; F157-I162 PolarHBondContact O-N 2.85Å; F157-H165 HydrophobicContact CD2-CB 3.87Å; F157-H165 HydrophobicContact CE2-CB 3.82Å
158E97.6Very high97.5Very high34 Ų3419.2 Ų19.216%0.1599%0.093CC..Hα-helixtrans-65.1-48.2172.7-172.969.8172.800111.6Y154 A155 L156 I160 N161 I237 R239 I244Y154-E158 PolarHBondContact O-N 2.64Å; A155-E158 PolarHBondContact O-N 3.27Å; L156-E158 VanDerWaalsContact C-N 3.28Å; L156-E158 PolarHBondContact O-N 3.27Å; E158-I160 VanDerWaalsContact C-N 3.3Å; E158-I160 PolarHBondContact O-N 3.23Å; E158-N161 PolarHBondContact O-N 2.89Å; E158-N161 VanDerWaalsContact O-N 3.07Å; E158-I237 HydrophobicContact CB-CB 4.37Å; E158-I237 HydrophobicContact CB-CG2 3.87Å; E158-I237 HydrophobicContact CG-CB 3.79Å; E158-I237 HydrophobicContact CG-CG2 3.55Å; E158-R239 VanDerWaalsContact CD-NE 3.33Å; E158-R239 IonicContact OE1-CZ 3.69Å; E158-R239 IonicContact OE1-NE 3.94Å; E158-R239 PolarHBondContact OE1-NE 3.28Å; E158-R239 IonicContact OE1-NH2 2.87Å; E158-R239 IonicContact OE2-CZ 3.65Å; E158-R239 IonicContact OE2-NE 2.85Å; E158-R239 PolarHBondContact OE2-NE 3.42Å; E158-R239 VanDerWaalsContact OE2-NE 3.09Å; E158-R239 IonicContact OE2-NH2 2.8Å; E158-R239 PolarHBondContact OE2-NH2 3.45Å; E158-I244 HydrophobicContact CB-CD1 3.85Å; E158-I244 HydrophobicContact CG-CD1 4.42Å
159A97.9Very high97.5Very high24 Ų2419.4 Ų19.420%0.1989%0.094CC..Hα-helixtrans-61.3-36.7-177.100000113L133 A155 L156 V235 I237L133-A159 HydrophobicContact CD1-CB 4.29Å; L133-A159 HydrophobicContact CD2-CB 4.23Å; A155-A159 WeakPolarHBondContact O-CB 3.35Å; A155-A159 PolarHBondContact O-N 2.92Å; L156-A159 PolarHBondContact O-N 3.36Å; L156-A159 VanDerWaalsContact O-N 3.15Å; A159-V235 HydrophobicContact CB-CG1 4.17Å; A159-V235 HydrophobicContact CB-CG2 4.02Å; A159-I237 HydrophobicContact CB-CG2 4.08Å
160I97.7Very high97.6Very high11 Ų1119 Ų196%0.0569%0.093CC..THydrogen-bonded Turntrans-90.3-2.3178.273.8178.2000113.3L23 L133 L136 K137 L156 E158 I162L23-I160 HydrophobicContact CD2-CD1 3.73Å; L133-I160 HydrophobicContact CD2-CG2 4.21Å; L136-I160 HydrophobicContact CB-CD1 4.35Å; L136-I160 HydrophobicContact CB-CG2 3.94Å; K137-I160 HydrophobicContact CB-CB 4.41Å; L156-I160 HydrophobicContact CD1-CG2 4.43Å; L156-I160 WeakPolarHBondContact O-CG1 3.39Å; L156-I160 PolarHBondContact O-N 3.48Å; E158-I160 VanDerWaalsContact C-N 3.3Å; E158-I160 PolarHBondContact O-N 3.23Å; I160-I162 HydrophobicContact CD1-CD1 4.48Å; I160-I162 HydrophobicContact CG1-CB 4.37Å
161N96.3Very high97.6Very high124 Ų12419.1 Ų19.166%0.66310%0.095SC*.THydrogen-bonded Turntrans55.252.7-177.2-169.640.4000113F157 E158 R163F157-N161 PolarHBondContact O-N 2.83Å; F157-N161 VanDerWaalsContact O-N 3.17Å; E158-N161 PolarHBondContact O-N 2.89Å; E158-N161 VanDerWaalsContact O-N 3.07Å; N161-R163 PolarHBondContact O-N 3.35Å
162I97.5Very high97.4Very high21 Ų2119.2 Ų19.211%0.10810%0.095CC..  trans-63.1137.4178.2-161.573.1000110.6A144 F157 I160 A164A144-I162 HydrophobicContact CB-CD1 4.05Å; A144-I162 HydrophobicContact CB-CG1 3.76Å; F157-I162 HydrophobicContact CB-CB 4.45Å; F157-I162 HydrophobicContact CB-CG2 3.57Å; F157-I162 HydrophobicContact CD2-CG2 4.4Å; F157-I162 HydrophobicContact CG-CG2 3.97Å; F157-I162 PolarHBondContact O-N 2.85Å; I160-I162 HydrophobicContact CD1-CD1 4.48Å; I160-I162 HydrophobicContact CG1-CB 4.37Å; I162-A164 WeakPolarHBondContact CG1-O 3.22Å
163R96.3Very high97.1Very high152 Ų15220.2 Ų20.257%0.57410%0.099SC*.SBendtrans-64-44.1179.8177.4-179.7167.1179.1-8.7112.4N161 K474N161-R163 PolarHBondContact O-N 3.35Å; R163-K474 WeakPolarHBondContact O-CE 3.45Å
164A98.2Very high96.9Very high0 Ų020.5 Ų20.50%010%0.1CC..  trans-154.9160.1-175.200000111.2L143 A144 I162 G473L143-A164 HydrophobicContact CD1-CB 3.82Å; A144-A164 PolarHBondContact N-O 3.23Å; I162-A164 WeakPolarHBondContact CG1-O 3.22Å; A164-G473 VanDerWaalsContact CB-CA 3.46Å
165H98.8Very high96.7Very high3 Ų320.5 Ų20.51%0.01410%0.1CC..EExtended strand (participates in β ladder)trans-147.8167.6176.363.7-82.6000112.1A144 Y154 F157 I244 A248 S249A144-H165 HydrophobicContact CB-CB 4.45Å; A144-H165 CarbonylContact O-C 3.54Å; A144-H165 WeakPolarHBondContact O-CA 3.31Å; A144-H165 WeakPolarHBondContact O-CB 3.46Å; Y154-H165 AromaticContact CE1-CD2 3.77Å; Y154-H165 AromaticContact CE1-NE2 3.79Å; F157-H165 HydrophobicContact CD2-CB 3.87Å; F157-H165 HydrophobicContact CE2-CB 3.82Å; H165-I244 PolarHBondContact CE1-O 3.21Å; H165-I244 PolarHBondContact NE2-O 3.42Å; H165-A248 WeakPolarHBondContact NE2-CA 3.41Å; H165-A248 WeakPolarHBondContact NE2-CB 3.16Å; H165-A248 PolarHBondContact NE2-N 2.93Å; H165-A248 WeakPolarHBondContact O-CA 3.15Å; H165-S249 PolarHBondContact O-N 3.01Å; H165-S249 PolarHBondContact O-OG 3.37Å
166V98.7Very high96.6Very high0 Ų020.4 Ų20.40%010%0.099CC..EExtended strand (participates in β ladder)trans-129.4152.7166.8-64.40000109.5L143 A144 I145 T146 F250 L252 V466 A469L143-V166 HydrophobicContact CD2-CG1 4.3Å; L143-V166 HydrophobicContact CD2-CG2 4.09Å; A144-V166 PolarHBondContact O-N 3.43Å; I145-V166 WeakPolarHBondContact CA-O 3.43Å; I145-V166 HydrophobicContact CB-CG2 4.22Å; I145-V166 HydrophobicContact CD1-CG2 3.95Å; I145-V166 HydrophobicContact CG1-CG2 3.6Å; I145-V166 HydrophobicContact CG2-CG2 4.12Å; T146-V166 PolarHBondContact N-O 2.93Å; V166-F250 HydrophobicContact CG1-CB 4.36Å; V166-F250 HydrophobicContact CG1-CD2 4.43Å; V166-L252 HydrophobicContact CG2-CD1 4.44Å; V166-V466 HydrophobicContact CG2-CG2 4.3Å; V166-A469 HydrophobicContact CG1-CB 3.63Å
167A98.6Very high96.5Very high0 Ų020.4 Ų20.40%010%0.099CC..EExtended strand (participates in β ladder)trans-101.8136.9172.800000109.7T146 P148 L169 L245 F250 I251 L252T146-A167 WeakPolarHBondContact O-CA 2.98Å; P148-A167 HydrophobicContact CG-CB 4.42Å; A167-L169 HydrophobicContact CB-CD1 4.4Å; A167-L245 HydrophobicContact CB-CD1 3.98Å; A167-F250 PolarHBondContact N-O 2.95Å; A167-F250 VanDerWaalsContact N-O 3.14Å; A167-I251 HydrophobicContact CB-CD1 3.7Å; A167-L252 WeakPolarHBondContact O-CB 3.15Å; A167-L252 PolarHBondContact O-N 3.44Å
168I98.6Very high96.3Very high1 Ų120.4 Ų20.41%0.00510%0.099CC..EExtended strand (participates in β ladder)trans-113.3119.7167.8-64.6178.5000108.3L37 A40 I145 T146 E147 L252 I272 L462L37-I168 HydrophobicContact CD2-CB 3.91Å; L37-I168 HydrophobicContact CD2-CD1 4.45Å; L37-I168 HydrophobicContact CD2-CG2 3.93Å; A40-I168 HydrophobicContact CB-CD1 3.67Å; I145-I168 HydrophobicContact CG2-CD1 3.55Å; I145-I168 HydrophobicContact CG2-CG1 3.77Å; T146-I168 PolarHBondContact O-N 3.26Å; E147-I168 VanDerWaalsContact CA-O 3.24Å; E147-I168 WeakPolarHBondContact CA-O 3.38Å; E147-I168 VanDerWaalsContact CB-O 3.28Å; E147-I168 WeakPolarHBondContact CB-O 3.41Å; E147-I168 VanDerWaalsContact CG-O 3.29Å; E147-I168 WeakPolarHBondContact CG-O 3.46Å; I168-L252 CarbonylContact C-O 3.51Å; I168-L252 WeakPolarHBondContact CA-O 3.16Å; I168-L252 HydrophobicContact CD1-CD1 4.36Å; I168-L252 HydrophobicContact CG1-CB 4.09Å; I168-L252 HydrophobicContact CG1-CD1 3.9Å; I168-I272 HydrophobicContact CG2-CD1 4.29Å; I168-L462 HydrophobicContact CD1-CD1 4.23Å
169L97.3Very high96.2Very high3 Ų323 Ų232%0.01611%0.114CC..EExtended strand (participates in β ladder)trans-91.7123.3172.3-79.465.4000108.7P148 A167 A171 F174 V177 I251 L252 T253 N254P148-L169 HydrophobicContact CG-CD1 3.61Å; P148-L169 HydrophobicContact CG-CG 4.09Å; A167-L169 HydrophobicContact CB-CD1 4.4Å; L169-A171 VanDerWaalsContact C-N 3.27Å; L169-F174 HydrophobicContact CB-CD2 4.37Å; L169-F174 HydrophobicContact CB-CE2 4.24Å; L169-F174 HydrophobicContact CD2-CB 4.35Å; L169-F174 HydrophobicContact CD2-CD2 3.76Å; L169-F174 HydrophobicContact CD2-CE2 4.44Å; L169-F174 HydrophobicContact CD2-CG 4.23Å; L169-F174 HydrophobicContact CG-CD2 3.61Å; L169-F174 HydrophobicContact CG-CE2 3.89Å; L169-V177 HydrophobicContact CD1-CG1 4.45Å; L169-V177 HydrophobicContact CD2-CG1 4.36Å; L169-I251 HydrophobicContact CD1-CG2 3.56Å; L169-L252 PolarHBondContact N-O 2.93Å; L169-T253 HydrophobicContact CD2-CG2 4.4Å; L169-N254 VanDerWaalsContact O-CB 3.3Å; L169-N254 WeakPolarHBondContact O-CB 3.3Å; L169-N254 PolarHBondContact O-N 3.46Å
170T95.4Very high96.1Very high11 Ų1122.2 Ų22.27%0.06711%0.107CC..SBendtrans-80-12.3174.569.40000113.1H33 V36 L37 E147 N254H33-T170 HydrophobicContact CB-CG2 4.35Å; H33-T170 PolarHBondContact CE1-OG1 3.31Å; H33-T170 PolarHBondContact ND1-OG1 3.47Å; V36-T170 HydrophobicContact CB-CG2 3.68Å; V36-T170 HydrophobicContact CG1-CG2 3.83Å; V36-T170 HydrophobicContact CG2-CG2 4.43Å; L37-T170 HydrophobicContact CD2-CG2 4.49Å; L37-T170 HydrophobicContact CG-CG2 4.04Å; E147-T170 VanDerWaalsContact OE1-CB 3.26Å; E147-T170 WeakPolarHBondContact OE1-CB 3.43Å; E147-T170 VanDerWaalsContact OE1-CG2 3.31Å; E147-T170 WeakPolarHBondContact OE1-CG2 3.42Å; E147-T170 PolarHBondContact OE1-N 3.15Å; E147-T170 PolarHBondContact OE1-OG1 2.95Å; T170-N254 WeakPolarHBondContact O-CB 3.3Å; T170-N254 PolarHBondContact O-ND2 3.02Å
171A94.6Very high96Very high7 Ų721.8 Ų21.86%0.05811%0.105CC..SBendtrans-94.6170.416700000112L169 R173 F174 N254L169-A171 VanDerWaalsContact C-N 3.27Å; A171-R173 VanDerWaalsContact C-N 3.27Å; A171-R173 PolarHBondContact O-N 3.33Å; A171-F174 HydrophobicContact CB-CD1 4.08Å; A171-F174 HydrophobicContact CB-CE1 3.49Å; A171-F174 VanDerWaalsContact CB-CE1 3.49Å; A171-F174 HydrophobicContact CB-CZ 3.82Å; A171-N254 PolarHBondContact O-N 3.27Å
172N92.8Very high95.9Very high6 Ų616.6 Ų16.63%0.0328%0.08CC..SBendtrans-60.2-40.5172.9-73.7-56.5000111.7Q255 L378 R402 N403N172-Q255 WeakPolarHBondContact OD1-CA 3.38Å; N172-L378 VanDerWaalsContact ND2-CD1 3.28Å; N172-L378 WeakPolarHBondContact ND2-CD1 3.42Å; N172-R402 PolarHBondContact ND2-NH1 2.97Å; N172-R402 VanDerWaalsContact ND2-NH1 3.16Å; N172-N403 PolarHBondContact ND2-OD1 3.21Å
173R91.7Very high95.7Very high20 Ų2016.5 Ų16.58%0.0758%0.079CC..  trans-158.7156.9-179.9-166.4174.470.1-128.9-4.4109A171 D175 T178 P191 T193A171-R173 VanDerWaalsContact C-N 3.27Å; A171-R173 PolarHBondContact O-N 3.33Å; R173-D175 IonicContact CZ-OD1 2.96Å; R173-D175 IonicContact NE-OD1 3.48Å; R173-D175 IonicContact NH2-OD1 2.67Å; R173-D175 PolarHBondContact NH2-OD1 2.94Å; R173-T178 WeakPolarHBondContact CD-OG1 3.33Å; R173-T178 WeakPolarHBondContact CG-OG1 3.44Å; R173-P191 PolarHBondContact NH2-O 3.07Å; R173-T193 WeakPolarHBondContact O-CG2 3.3Å; R173-T193 PolarHBondContact O-OG1 2.84Å
174F94.2Very high95.5Very high7 Ų710.9 Ų10.93%0.0316%0.063CC..  trans-121.8134.6159.7-61.2-54.1000110E147 P148 F149 L169 A171 H176 V177 T178 T193E147-F174 HydrophobicContact CG-CE2 4.12Å; E147-F174 WeakPolarHBondContact OE1-CZ 3.32Å; P148-F174 HydrophobicContact CG-CD2 4.27Å; F149-F174 HydrophobicContact CB-CE2 4.1Å; F149-F174 HydrophobicContact CB-CZ 4.12Å; F149-F174 HydrophobicContact CD2-CE1 4.14Å; F149-F174 AromaticContact CD2-CZ 3.94Å; F149-F174 HydrophobicContact CD2-CZ 3.94Å; F149-F174 HydrophobicContact CG-CZ 4.47Å; L169-F174 HydrophobicContact CB-CD2 4.37Å; L169-F174 HydrophobicContact CB-CE2 4.24Å; L169-F174 HydrophobicContact CD2-CB 4.35Å; L169-F174 HydrophobicContact CD2-CD2 3.76Å; L169-F174 HydrophobicContact CD2-CE2 4.44Å; L169-F174 HydrophobicContact CD2-CG 4.23Å; L169-F174 HydrophobicContact CG-CD2 3.61Å; L169-F174 HydrophobicContact CG-CE2 3.89Å; A171-F174 HydrophobicContact CB-CD1 4.08Å; A171-F174 HydrophobicContact CB-CE1 3.49Å; A171-F174 VanDerWaalsContact CB-CE1 3.49Å; A171-F174 HydrophobicContact CB-CZ 3.82Å; F174-H176 VanDerWaalsContact C-N 3.35Å; F174-H176 WeakPolarHBondContact CB-CE1 3.27Å; F174-H176 VanDerWaalsContact CB-ND1 3.33Å; F174-H176 WeakPolarHBondContact CB-ND1 3.45Å; F174-H176 AromaticContact CD2-CE1 3.99Å; F174-H176 AromaticContact CG-CE1 3.76Å; F174-H176 PolarHBondContact O-N 2.79Å; F174-V177 HydrophobicContact CB-CB 4.18Å; F174-V177 HydrophobicContact CB-CG2 3.88Å; F174-V177 HydrophobicContact CD2-CG2 4.16Å; F174-V177 PolarHBondContact O-N 3.41Å; F174-T178 PolarHBondContact O-N 2.92Å; F174-T178 PolarHBondContact O-OG1 3.23Å; F174-T193 HydrophobicContact CD1-CG2 4.44Å
175D94Very high94.9Very high0 Ų014 Ų140%08%0.079CC..Hα-helixtrans-67.1-35.2-173.5-61.4-30.1000111.9R173 T178 D179 T193 F213R173-D175 IonicContact CZ-OD1 2.96Å; R173-D175 IonicContact NE-OD1 3.48Å; R173-D175 IonicContact NH2-OD1 2.67Å; R173-D175 PolarHBondContact NH2-OD1 2.94Å; D175-T178 WeakPolarHBondContact O-CB 3.39Å; D175-T178 PolarHBondContact O-N 3.37Å; D175-D179 PolarHBondContact O-N 3.46Å; D175-T193 PolarHBondContact N-OG1 2.83Å; D175-T193 PolarHBondContact OD1-N 3.25Å; D175-T193 PolarHBondContact OD1-OG1 2.86Å; D175-T193 VanDerWaalsContact OD2-CB 3.3Å; D175-T193 WeakPolarHBondContact OD2-CB 3.46Å; D175-T193 PolarHBondContact OD2-N 3.34Å; D175-T193 PolarHBondContact OD2-OG1 2.79Å; D175-F213 HydrophobicContact CB-CD2 3.91Å; D175-F213 HydrophobicContact CB-CE2 3.62Å; D175-F213 HydrophobicContact CB-CZ 3.99Å; D175-F213 WeakPolarHBondContact OD1-CD2 3.35Å; D175-F213 WeakPolarHBondContact OD1-CE2 3.37Å
176H94.8Very high94.6Very high1 Ų114.8 Ų14.81%0.0059%0.085CC..Hα-helixtrans-68.6-34.9175.470.1-61000112.9P148 F174 T178 V180 S217 F220 W241P148-H176 PolarHBondContact O-NE2 3.45Å; F174-H176 VanDerWaalsContact C-N 3.35Å; F174-H176 WeakPolarHBondContact CB-CE1 3.27Å; F174-H176 VanDerWaalsContact CB-ND1 3.33Å; F174-H176 WeakPolarHBondContact CB-ND1 3.45Å; F174-H176 AromaticContact CD2-CE1 3.99Å; F174-H176 AromaticContact CG-CE1 3.76Å; F174-H176 PolarHBondContact O-N 2.79Å; H176-T178 VanDerWaalsContact C-N 3.35Å; H176-V180 VanDerWaalsContact O-CB 3.3Å; H176-V180 WeakPolarHBondContact O-CB 3.41Å; H176-V180 WeakPolarHBondContact O-CG2 3.42Å; H176-V180 PolarHBondContact O-N 3.43Å; H176-S217 WeakPolarHBondContact CA-OG 3.26Å; H176-S217 WeakPolarHBondContact CB-O 3.37Å; H176-F220 HydrophobicContact CB-CB 3.99Å; H176-F220 AromaticContact CE1-CG 3.97Å; H176-F220 VanDerWaalsContact CG-CB 3.46Å; H176-F220 VanDerWaalsContact ND1-CB 3.26Å; H176-F220 WeakPolarHBondContact ND1-CB 3.37Å; H176-F220 AromaticContact ND1-CG 3.86Å; H176-W241 HydrophobicContact CB-CH2 4.14Å; H176-W241 AromaticContact CD2-CH2 3.67Å; H176-W241 AromaticContact CD2-CZ3 3.77Å
177V96.7Very high94.3Very high1 Ų116.1 Ų16.11%0.00610%0.095CC..Hα-helixtrans-64.8-45.2172.3173.10000109.6P148 L169 F174 D179 V180 I181 L245 I251P148-V177 HydrophobicContact CB-CG2 3.61Å; P148-V177 HydrophobicContact CG-CG2 3.39Å; L169-V177 HydrophobicContact CD1-CG1 4.45Å; L169-V177 HydrophobicContact CD2-CG1 4.36Å; F174-V177 HydrophobicContact CB-CB 4.18Å; F174-V177 HydrophobicContact CB-CG2 3.88Å; F174-V177 HydrophobicContact CD2-CG2 4.16Å; F174-V177 PolarHBondContact O-N 3.41Å; V177-D179 PolarHBondContact O-N 3.1Å; V177-V180 PolarHBondContact O-N 3.31Å; V177-I181 HydrophobicContact CG1-CD1 4.01Å; V177-I181 HydrophobicContact CG1-CG2 4.26Å; V177-I181 WeakPolarHBondContact O-CG1 3.39Å; V177-I181 WeakPolarHBondContact O-CG2 3.43Å; V177-I181 PolarHBondContact O-N 3.47Å; V177-L245 HydrophobicContact CB-CD2 4.37Å; V177-L245 HydrophobicContact CG1-CD2 4.23Å; V177-L245 HydrophobicContact CG2-CD2 4.05Å; V177-I251 HydrophobicContact CG1-CG2 4.31Å
178T95.2Very high94Very high2 Ų218.9 Ų18.91%0.01211%0.114CC..Hα-helixtrans-58.6-48.8-178.9-54.30000111R173 F174 D175 H176 G182 Q183 I185 F213R173-T178 WeakPolarHBondContact CD-OG1 3.33Å; R173-T178 WeakPolarHBondContact CG-OG1 3.44Å; F174-T178 PolarHBondContact O-N 2.92Å; F174-T178 PolarHBondContact O-OG1 3.23Å; D175-T178 WeakPolarHBondContact O-CB 3.39Å; D175-T178 PolarHBondContact O-N 3.37Å; H176-T178 VanDerWaalsContact C-N 3.35Å; T178-G182 PolarHBondContact O-N 2.9Å; T178-Q183 HydrophobicContact CG2-CB 3.62Å; T178-Q183 HydrophobicContact CG2-CG 3.91Å; T178-Q183 PolarHBondContact O-N 2.92Å; T178-I185 HydrophobicContact CG2-CD1 3.74Å; T178-I185 HydrophobicContact CG2-CG1 3.36Å; T178-F213 HydrophobicContact CG2-CE2 4.33Å; T178-F213 HydrophobicContact CG2-CZ 4.07Å
179D94.1Very high93.9Very high88 Ų8823.3 Ų23.347%0.47113%0.131SC..Hα-helixtrans-59.5-54.5175.4-178.146.1000110.9D175 V177 I181 G182D175-D179 PolarHBondContact O-N 3.46Å; V177-D179 PolarHBondContact O-N 3.1Å; D179-I181 VanDerWaalsContact C-N 3.31Å; D179-I181 PolarHBondContact O-N 2.98Å; D179-G182 PolarHBondContact O-N 3.46Å; D179-G182 VanDerWaalsContact O-N 3.08Å
180V95.7Very high93.8Very high8 Ų823.6 Ų23.65%0.04813%0.133CC..Hα-helixtrans-68-25.6-175.71680000112.8H176 V177 W241 R242 L245 P246 R483H176-V180 VanDerWaalsContact O-CB 3.3Å; H176-V180 WeakPolarHBondContact O-CB 3.41Å; H176-V180 WeakPolarHBondContact O-CG2 3.42Å; H176-V180 PolarHBondContact O-N 3.43Å; V177-V180 PolarHBondContact O-N 3.31Å; V180-W241 HydrophobicContact CB-CH2 4.35Å; V180-W241 HydrophobicContact CB-CZ3 3.92Å; V180-W241 HydrophobicContact CG1-CE3 4.41Å; V180-W241 HydrophobicContact CG1-CZ3 4.01Å; V180-W241 HydrophobicContact CG2-CH2 3.51Å; V180-W241 HydrophobicContact CG2-CZ2 4.46Å; V180-W241 HydrophobicContact CG2-CZ3 3.56Å; V180-R242 HydrophobicContact CG1-CB 4.32Å; V180-R242 HydrophobicContact CG2-CB 4.46Å; V180-R242 HydrophobicContact CG2-CG 3.93Å; V180-L245 HydrophobicContact CB-CD2 4.45Å; V180-L245 HydrophobicContact CG1-CD2 4.07Å; V180-P246 HydrophobicContact CG1-CG 3.8Å; V180-P246 WeakPolarHBondContact O-CG 3.32Å; V180-R483 PolarHBondContact O-NH1 2.84Å; V180-R483 PolarHBondContact O-NH2 3.35Å
181I96.1Very high93.8Very high3 Ų323 Ų232%0.01513%0.13CC..Hα-helixtrans-91.3-5.1175.172.4-171.3000113.5V177 D179 Q183 L245 I251 F266 I269 R483V177-I181 HydrophobicContact CG1-CD1 4.01Å; V177-I181 HydrophobicContact CG1-CG2 4.26Å; V177-I181 WeakPolarHBondContact O-CG1 3.39Å; V177-I181 WeakPolarHBondContact O-CG2 3.43Å; V177-I181 PolarHBondContact O-N 3.47Å; D179-I181 VanDerWaalsContact C-N 3.31Å; D179-I181 PolarHBondContact O-N 2.98Å; I181-Q183 HydrophobicContact CD1-CB 3.99Å; I181-Q183 HydrophobicContact CG1-CB 3.79Å; I181-L245 HydrophobicContact CG2-CD2 4.41Å; I181-L245 HydrophobicContact CG2-CG 4.11Å; I181-I251 HydrophobicContact CD1-CG1 4.12Å; I181-I251 HydrophobicContact CG2-CD1 4.37Å; I181-I251 HydrophobicContact CG2-CG1 4.49Å; I181-F266 HydrophobicContact CD1-CZ 4.32Å; I181-F266 HydrophobicContact CG1-CZ 4.09Å; I181-I269 HydrophobicContact CD1-CD1 3.45Å; I181-I269 VanDerWaalsContact CD1-CD1 3.45Å; I181-R483 VanDerWaalsContact C-NH1 3.29Å; I181-R483 PolarHBondContact O-NH1 2.94Å
182G94.2Very high93.7Very high14 Ų1422.7 Ų22.714%0.14413%0.127CC..THydrogen-bonded Turntrans69.330.3-172.700000113.2T178 D179 P184 N480T178-G182 PolarHBondContact O-N 2.9Å; D179-G182 PolarHBondContact O-N 3.46Å; D179-G182 VanDerWaalsContact O-N 3.08Å; G182-P184 WeakPolarHBondContact O-CD 3.45Å; G182-N480 PolarHBondContact O-ND2 3.26Å
183Q94.7Very high93.7Very high19 Ų1922.7 Ų22.79%0.08913%0.127CC..  trans-65.3125.3173.4177.4176.23.500110T178 I181 I185 F266T178-Q183 HydrophobicContact CG2-CB 3.62Å; T178-Q183 HydrophobicContact CG2-CG 3.91Å; T178-Q183 PolarHBondContact O-N 2.92Å; I181-Q183 HydrophobicContact CD1-CB 3.99Å; I181-Q183 HydrophobicContact CG1-CB 3.79Å; Q183-I185 WeakPolarHBondContact O-CG1 3.45Å; Q183-I185 PolarHBondContact O-N 3.44Å; Q183-F266 VanDerWaalsContact CA-CE1 3.45Å; Q183-F266 HydrophobicContact CB-CE1 3.98Å; Q183-F266 HydrophobicContact CB-CZ 4.4Å
184P91Very high93.6Very high35 Ų3523.4 Ų23.423%0.22713%0.131CC..  trans-60.5126.6-177.1-22.831.7000111.6G182 P264G182-P184 WeakPolarHBondContact O-CD 3.45Å; P184-P264 HydrophobicContact CB-CB 3.88Å
185I84.7Confident93.5Very high65 Ų6523.4 Ų23.433%0.33313%0.132SC..  trans-106.3115.4-178.4-62132.8000109.5T178 Q183 F213T178-I185 HydrophobicContact CG2-CD1 3.74Å; T178-I185 HydrophobicContact CG2-CG1 3.36Å; Q183-I185 WeakPolarHBondContact O-CG1 3.45Å; Q183-I185 PolarHBondContact O-N 3.44Å; I185-F213 HydrophobicContact CB-CZ 4.37Å; I185-F213 HydrophobicContact CD1-CD1 4.48Å; I185-F213 HydrophobicContact CD1-CE1 3.41Å; I185-F213 VanDerWaalsContact CD1-CE1 3.41Å; I185-F213 HydrophobicContact CD1-CE2 4.09Å; I185-F213 HydrophobicContact CD1-CZ 3.18Å; I185-F213 HydrophobicContact CG1-CE1 4.02Å; I185-F213 HydrophobicContact CG1-CE2 3.81Å; I185-F213 HydrophobicContact CG1-CZ 3.42Å; I185-F213 VanDerWaalsContact CG1-CZ 3.42Å; I185-F213 HydrophobicContact CG2-CD1 4.43Å; I185-F213 HydrophobicContact CG2-CD2 4.07Å; I185-F213 HydrophobicContact CG2-CE1 4.32Å; I185-F213 HydrophobicContact CG2-CE2 3.93Å; I185-F213 HydrophobicContact CG2-CG 4.34Å; I185-F213 HydrophobicContact CG2-CZ 4.1Å
186A92.7Very high93.3Very high19 Ų1928.9 Ų28.916%0.15716%0.158CC..  trans-101.668.3169.300000110.6S188 Y189 V190 P264A186-S188 PolarHBondContact O-N 2.91Å; A186-Y189 HydrophobicContact CB-CD1 4.03Å; A186-Y189 HydrophobicContact CB-CE1 3.33Å; A186-Y189 HydrophobicContact CB-CE2 4.13Å; A186-Y189 WeakPolarHBondContact CB-OH 3.46Å; A186-Y189 PolarHBondContact O-N 3.4Å; A186-V190 HydrophobicContact CB-CG2 4.14Å; A186-V190 WeakPolarHBondContact O-CB 3.28Å; A186-V190 PolarHBondContact O-N 3.44Å; A186-P264 HydrophobicContact CB-CG 4.02Å
187S92.4Very high93.2Very high28 Ų2830 Ų3020%0.19616%0.164CC..THydrogen-bonded Turntrans-60.3-9.8-176.155.90000114.6Y189 N209S187-Y189 VanDerWaalsContact C-N 3.3Å; S187-N209 PolarHBondContact O-ND2 2.9Å
188S94.2Very high93.1Very high58 Ų5830.5 Ų30.541%0.40617%0.17SC..THydrogen-bonded Turntrans-72.6-20173.859.30000114.1A186 R206A186-S188 PolarHBondContact O-N 2.91Å; S188-R206 VanDerWaalsContact O-CD 3.3Å; S188-R206 WeakPolarHBondContact O-CD 3.41Å; S188-R206 WeakPolarHBondContact O-CG 3.38Å
189Y95Very high93.1Very high95 Ų9532.2 Ų32.237%0.37318%0.179SC..THydrogen-bonded Turntrans-146.3-7.5177.966.4-97.2000114.1A186 S187 P191 D199 P264A186-Y189 HydrophobicContact CB-CD1 4.03Å; A186-Y189 HydrophobicContact CB-CE1 3.33Å; A186-Y189 HydrophobicContact CB-CE2 4.13Å; A186-Y189 WeakPolarHBondContact CB-OH 3.46Å; A186-Y189 PolarHBondContact O-N 3.4Å; S187-Y189 VanDerWaalsContact C-N 3.3Å; Y189-P191 WeakPolarHBondContact O-CD 3.31Å; Y189-D199 WeakPolarHBondContact O-CA 3.31Å; Y189-D199 WeakPolarHBondContact O-CB 3.3Å; Y189-P264 WeakPolarHBondContact OH-CD 3.44Å; Y189-P264 WeakPolarHBondContact OH-CG 3.47Å
190V95.7Very high93.2Very high8 Ų838.3 Ų38.35%0.04820%0.196CC..SBendtrans-98.4113.4173.5-1790000108.3A186 G192 N209 A263A186-V190 HydrophobicContact CB-CG2 4.14Å; A186-V190 WeakPolarHBondContact O-CB 3.28Å; A186-V190 PolarHBondContact O-N 3.44Å; V190-G192 PolarHBondContact O-N 3.35Å; V190-N209 PolarHBondContact O-ND2 2.76Å; V190-A263 HydrophobicContact CG1-CB 4.02Å; V190-A263 HydrophobicContact CG2-CB 3.69Å
191P95.1Very high93.2Very high0 Ų039.2 Ų39.20%020%0.2CC..  trans-63.3135.6176.8-21.133.1000110.6R173 Y189 T197 M201 N209 F261 R402R173-P191 PolarHBondContact NH2-O 3.07Å; Y189-P191 WeakPolarHBondContact O-CD 3.31Å; P191-T197 WeakPolarHBondContact CB-O 3.42Å; P191-T197 WeakPolarHBondContact CG-O 3.47Å; P191-M201 HydrophobicContact CB-CE 4.17Å; P191-M201 HydrophobicContact CG-CE 3.8Å; P191-N209 VanDerWaalsContact CA-OD1 3.26Å; P191-N209 WeakPolarHBondContact CA-OD1 3.38Å; P191-F261 HydrophobicContact CG-CD2 4.09Å; P191-F261 HydrophobicContact CG-CE1 4.4Å; P191-F261 HydrophobicContact CG-CE2 3.82Å; P191-F261 HydrophobicContact CG-CG 4.47Å; P191-F261 HydrophobicContact CG-CZ 3.97Å; P191-R402 HydrophobicContact CB-CG 4.29Å
192G93.1Very high93.3Very high0 Ų043.2 Ų43.20%022%0.224CC..  trans-66.9170.7171.100000111.9V190 Q194 S195 N209 R402V190-G192 PolarHBondContact O-N 3.35Å; G192-Q194 VanDerWaalsContact C-N 3.3Å; G192-Q194 PolarHBondContact O-N 3.27Å; G192-S195 VanDerWaalsContact O-CB 3.31Å; G192-S195 WeakPolarHBondContact O-CB 3.39Å; G192-S195 PolarHBondContact O-N 3.46Å; G192-S195 VanDerWaalsContact O-N 3.14Å; G192-N209 PolarHBondContact N-OD1 3.15Å; G192-R402 WeakPolarHBondContact O-CD 3.48Å
193T92.4Very high93.4Very high5 Ų549.7 Ų49.73%0.03125%0.253CS..THydrogen-bonded Turntrans-60.1-39.2-166.8-60.10000112.5R173 F174 D175 D399R173-T193 WeakPolarHBondContact O-CG2 3.3Å; R173-T193 PolarHBondContact O-OG1 2.84Å; F174-T193 HydrophobicContact CD1-CG2 4.44Å; D175-T193 PolarHBondContact N-OG1 2.83Å; D175-T193 PolarHBondContact OD1-N 3.25Å; D175-T193 PolarHBondContact OD1-OG1 2.86Å; D175-T193 VanDerWaalsContact OD2-CB 3.3Å; D175-T193 WeakPolarHBondContact OD2-CB 3.46Å; D175-T193 PolarHBondContact OD2-N 3.34Å; D175-T193 PolarHBondContact OD2-OG1 2.79Å; T193-D399 HydrophobicContact CG2-CB 4.26Å; T193-D399 VanDerWaalsContact O-CA 3.28Å; T193-D399 WeakPolarHBondContact O-CA 3.15Å; T193-D399 WeakPolarHBondContact O-CB 3.48Å
194Q89.3Confident93.5Very high36 Ų3651.2 Ų51.217%0.16827%0.273CS..THydrogen-bonded Turntrans-10619.4-179.4-50.5-177.371.300112.5M108 G192 Q212 A398M108-Q194 VanDerWaalsContact CE-NE2 3.25Å; G192-Q194 VanDerWaalsContact C-N 3.3Å; G192-Q194 PolarHBondContact O-N 3.27Å; Q194-Q212 HydrophobicContact CB-CG 4.35Å; Q194-Q212 VanDerWaalsContact N-NE2 3.14Å; Q194-A398 WeakPolarHBondContact CA-O 3.3Å
195S91.8Very high93.7Very high6 Ų653 Ų534%0.04228%0.279CS..  trans-75.4143.3178.7-175.40000111.2G192 T197 N209 G401 R402G192-S195 VanDerWaalsContact O-CB 3.31Å; G192-S195 WeakPolarHBondContact O-CB 3.39Å; G192-S195 PolarHBondContact O-N 3.46Å; G192-S195 VanDerWaalsContact O-N 3.14Å; S195-T197 PolarHBondContact OG-N 3.11Å; S195-T197 PolarHBondContact OG-OG1 2.96Å; S195-N209 VanDerWaalsContact CB-OD1 3.29Å; S195-N209 WeakPolarHBondContact CB-OD1 3.41Å; S195-N209 PolarHBondContact OG-OD1 3.21Å; S195-G401 CarbonylContact O-C 3.57Å; S195-R402 VanDerWaalsContact O-CA 3.3Å; S195-R402 WeakPolarHBondContact O-CA 3.34Å; S195-R402 WeakPolarHBondContact O-CB 3.26Å; S195-R402 PolarHBondContact O-N 2.95Å
196E91.1Very high94.3Very high116 Ų11655.4 Ų55.454%0.54228%0.284SS..  trans-95.72.6174.5-59.4-169.4156.700113Q405E196-Q405 VanDerWaalsContact O-CG 3.23Å; E196-Q405 WeakPolarHBondContact O-CG 3.39Å; E196-Q405 PolarHBondContact O-NE2 3.16Å
197T92.8Very high94.4Very high23 Ų2359.4 Ų59.414%0.14130%0.302CS..  trans-99.9157.1-17666.90000112.2P191 S195 M201 E205P191-T197 WeakPolarHBondContact CB-O 3.42Å; P191-T197 WeakPolarHBondContact CG-O 3.47Å; S195-T197 PolarHBondContact OG-N 3.11Å; S195-T197 PolarHBondContact OG-OG1 2.96Å; T197-M201 WeakPolarHBondContact OG1-CE 3.25Å; T197-E205 HydrophobicContact CG2-CB 3.97Å; T197-E205 HydrophobicContact CG2-CG 3.87Å
198G94.2Very high94.4Very high13 Ų1360 Ų6013%0.13431%0.313CS..  trans-90.6-171.9172.700000112.3R200 M201G198-R200 PolarHBondContact O-N 2.97Å; G198-M201 WeakPolarHBondContact O-CE 3.41Å; G198-M201 WeakPolarHBondContact O-CG 3.32Å
199D95.1Very high94.5Very high37 Ų3757.3 Ų57.320%0.19829%0.294CS..SBendtrans-75.6-6.1177.866.5-23.6000115Y189 F261 R409Y189-D199 WeakPolarHBondContact O-CA 3.31Å; Y189-D199 WeakPolarHBondContact O-CB 3.3Å; D199-F261 HydrophobicContact CB-CD1 3.77Å; D199-F261 HydrophobicContact CB-CE1 4.13Å; D199-R409 IonicContact OD1-CZ 3.44Å; D199-R409 IonicContact OD1-NH1 3.13Å; D199-R409 PolarHBondContact OD1-NH1 3.23Å; D199-R409 IonicContact OD1-NH2 3.07Å; D199-R409 IonicContact OD2-CZ 3.72Å; D199-R409 IonicContact OD2-NH1 3.37Å; D199-R409 PolarHBondContact OD2-NH1 2.96Å; D199-R409 IonicContact OD2-NH2 2.9Å; D199-R409 PolarHBondContact OD2-NH2 3.29Å
200R95.8Very high94.4Very high217 Ų21757.6 Ų57.682%0.81930%0.295SS*.SBendtrans-109.287.6175.7-64.1-176.3-178.5-158.5-0.5109G198G198-R200 PolarHBondContact O-N 2.97Å
201M96.1Very high94.2Very high26 Ų2662.5 Ų62.513%0.12832%0.316CS..  trans-105.2138-174.1-60.7176.7-160.500111.7P191 T197 G198 E205 R206 N209P191-M201 HydrophobicContact CB-CE 4.17Å; P191-M201 HydrophobicContact CG-CE 3.8Å; T197-M201 WeakPolarHBondContact OG1-CE 3.25Å; G198-M201 WeakPolarHBondContact O-CE 3.41Å; G198-M201 WeakPolarHBondContact O-CG 3.32Å; M201-E205 HydrophobicContact CB-CB 3.75Å; M201-E205 HydrophobicContact CG-CB 4.16Å; M201-R206 HydrophobicContact CB-CG 3.52Å; M201-R206 HydrophobicContact CG-CG 4.44Å; M201-R206 HydrophobicContact SD-CG 4.14Å; M201-N209 HydrophobicContact CE-CB 4.1Å; M201-N209 HydrophobicContact SD-CB 3.7Å
202T97.2Very high93.9Very high87 Ų8763.7 Ų63.753%0.53432%0.321SS..  trans-65.3171160.962.80000111G204 E205 R206T202-G204 VanDerWaalsContact C-N 3.32Å; T202-G204 PolarHBondContact O-N 3.46Å; T202-E205 WeakPolarHBondContact CB-OE2 3.48Å; T202-E205 VanDerWaalsContact CG2-OE2 3.3Å; T202-E205 WeakPolarHBondContact CG2-OE2 3.24Å; T202-E205 PolarHBondContact N-OE2 3.23Å; T202-E205 PolarHBondContact O-N 3.13Å; T202-E205 WeakPolarHBondContact OG1-CG 3.36Å; T202-E205 PolarHBondContact OG1-N 3.02Å; T202-E205 PolarHBondContact OG1-OE2 2.94Å; T202-R206 WeakPolarHBondContact O-CG 3.42Å; T202-R206 PolarHBondContact O-N 3.42Å
203M97.2Very high93.8Very high150 Ų15064.5 Ų64.574%0.73933%0.325SS*.Hα-helixtrans-58.6-42.3177.5-173.4174.576.600112.9R206 L207M203-R206 PolarHBondContact O-N 2.92Å; M203-L207 PolarHBondContact O-N 3.01Å; M203-L207 VanDerWaalsContact O-N 3.1Å
204G96.4Very high93.7Very high51 Ų5168 Ų6853%0.52634%0.343SS..Hα-helixtrans-65.4-43.3177.600000112.2T202 R206 L207 G208T202-G204 VanDerWaalsContact C-N 3.32Å; T202-G204 PolarHBondContact O-N 3.46Å; G204-R206 VanDerWaalsContact C-N 3.35Å; G204-R206 PolarHBondContact O-N 3.09Å; G204-L207 PolarHBondContact O-N 2.9Å; G204-G208 PolarHBondContact O-N 3.36Å
205E95.7Very high93.7Very high74 Ų7468.5 Ų68.535%0.34635%0.348SS..Hα-helixtrans-64.2-37.4176-72.6167.4132.200112.3T197 M201 T202 G208 N209T197-E205 HydrophobicContact CG2-CB 3.97Å; T197-E205 HydrophobicContact CG2-CG 3.87Å; M201-E205 HydrophobicContact CB-CB 3.75Å; M201-E205 HydrophobicContact CG-CB 4.16Å; T202-E205 WeakPolarHBondContact CB-OE2 3.48Å; T202-E205 VanDerWaalsContact CG2-OE2 3.3Å; T202-E205 WeakPolarHBondContact CG2-OE2 3.24Å; T202-E205 PolarHBondContact N-OE2 3.23Å; T202-E205 PolarHBondContact O-N 3.13Å; T202-E205 WeakPolarHBondContact OG1-CG 3.36Å; T202-E205 PolarHBondContact OG1-N 3.02Å; T202-E205 PolarHBondContact OG1-OE2 2.94Å; E205-G208 PolarHBondContact O-N 3.22Å; E205-N209 WeakPolarHBondContact O-CB 3.4Å; E205-N209 PolarHBondContact O-N 3.13Å
206R96.9Very high93.5Very high115 Ų11568.2 Ų68.243%0.43435%0.346SS..Hα-helixtrans-63.5-42.3173.6-71.4-170.6-56.6-177.43.4112S188 M201 T202 M203 G204 N209 Y210S188-R206 VanDerWaalsContact O-CD 3.3Å; S188-R206 WeakPolarHBondContact O-CD 3.41Å; S188-R206 WeakPolarHBondContact O-CG 3.38Å; M201-R206 HydrophobicContact CB-CG 3.52Å; M201-R206 HydrophobicContact CG-CG 4.44Å; M201-R206 HydrophobicContact SD-CG 4.14Å; T202-R206 WeakPolarHBondContact O-CG 3.42Å; T202-R206 PolarHBondContact O-N 3.42Å; M203-R206 PolarHBondContact O-N 2.92Å; G204-R206 VanDerWaalsContact C-N 3.35Å; G204-R206 PolarHBondContact O-N 3.09Å; R206-N209 PolarHBondContact O-N 3.2Å; R206-Y210 WeakPolarHBondContact O-CB 3.28Å; R206-Y210 PolarHBondContact O-N 3.05Å
207L95.2Very high93.5Very high102 Ų10263.1 Ų63.153%0.53432%0.324SS..Hα-helixtrans-64.1-46.3176.8-176.863.1000110.9M203 G204 N209 Y210 F211M203-L207 PolarHBondContact O-N 3.01Å; M203-L207 VanDerWaalsContact O-N 3.1Å; G204-L207 PolarHBondContact O-N 2.9Å; L207-N209 PolarHBondContact O-N 2.99Å; L207-Y210 WeakPolarHBondContact O-CB 3.13Å; L207-Y210 PolarHBondContact O-N 3.3Å; L207-F211 HydrophobicContact CD1-CD2 4.09Å; L207-F211 HydrophobicContact CD1-CE2 3.58Å; L207-F211 HydrophobicContact CD1-CZ 4.49Å; L207-F211 HydrophobicContact CD2-CE2 4.48Å; L207-F211 HydrophobicContact CG-CD2 4.08Å; L207-F211 HydrophobicContact CG-CE2 3.84Å; L207-F211 VanDerWaalsContact O-CD2 3.25Å; L207-F211 WeakPolarHBondContact O-CD2 3.41Å; L207-F211 PolarHBondContact O-N 3.03Å; L207-F211 VanDerWaalsContact O-N 3.12Å
208G92.7Very high93.5Very high41 Ų4168.2 Ų68.242%0.42334%0.341SS..Hα-helixtrans-60.1-44175.400000112.4G204 E205 Y210 F211 Q212G204-G208 PolarHBondContact O-N 3.36Å; E205-G208 PolarHBondContact O-N 3.22Å; G208-Y210 PolarHBondContact O-N 3.17Å; G208-F211 PolarHBondContact O-N 2.94Å; G208-Q212 WeakPolarHBondContact O-CB 3.29Å; G208-Q212 PolarHBondContact O-N 3.12Å
209N94.7Very high93.2Very high2 Ų268.2 Ų68.21%0.01134%0.338CS..Hα-helixtrans-63.7-39.2177.4-171.863.6000112.6S187 V190 P191 G192 S195 M201 E205 R206 L207 Q212 F213S187-N209 PolarHBondContact O-ND2 2.9Å; V190-N209 PolarHBondContact O-ND2 2.76Å; P191-N209 VanDerWaalsContact CA-OD1 3.26Å; P191-N209 WeakPolarHBondContact CA-OD1 3.38Å; G192-N209 PolarHBondContact N-OD1 3.15Å; S195-N209 VanDerWaalsContact CB-OD1 3.29Å; S195-N209 WeakPolarHBondContact CB-OD1 3.41Å; S195-N209 PolarHBondContact OG-OD1 3.21Å; M201-N209 HydrophobicContact CE-CB 4.1Å; M201-N209 HydrophobicContact SD-CB 3.7Å; E205-N209 WeakPolarHBondContact O-CB 3.4Å; E205-N209 PolarHBondContact O-N 3.13Å; R206-N209 PolarHBondContact O-N 3.2Å; L207-N209 PolarHBondContact O-N 2.99Å; N209-Q212 PolarHBondContact O-N 3.27Å; N209-F213 PolarHBondContact O-N 3.47Å
210Y93.5Very high92.9Very high100 Ų10067.4 Ų67.439%0.39233%0.332SS..Hα-helixtrans-60.2-47.8174.2176.6-104.1000111.7R206 L207 G208 Q212 F213 L214R206-Y210 WeakPolarHBondContact O-CB 3.28Å; R206-Y210 PolarHBondContact O-N 3.05Å; L207-Y210 WeakPolarHBondContact O-CB 3.13Å; L207-Y210 PolarHBondContact O-N 3.3Å; G208-Y210 PolarHBondContact O-N 3.17Å; Y210-Q212 VanDerWaalsContact C-N 3.35Å; Y210-Q212 PolarHBondContact O-N 2.92Å; Y210-F213 PolarHBondContact O-N 3.03Å; Y210-L214 HydrophobicContact CD1-CD1 4.16Å; Y210-L214 HydrophobicContact CE1-CD1 3.56Å; Y210-L214 HydrophobicContact CE1-CG 4.38Å; Y210-L214 PolarHBondContact O-N 3.36Å
211F91.3Very high92.9Very high112 Ų11257.4 Ų57.449%0.49130%0.295SS..Hα-helixtrans-64.8-38.4175.8-78.1-65000112.6L207 G208 F213 L214 V215L207-F211 HydrophobicContact CD1-CD2 4.09Å; L207-F211 HydrophobicContact CD1-CE2 3.58Å; L207-F211 HydrophobicContact CD1-CZ 4.49Å; L207-F211 HydrophobicContact CD2-CE2 4.48Å; L207-F211 HydrophobicContact CG-CD2 4.08Å; L207-F211 HydrophobicContact CG-CE2 3.84Å; L207-F211 VanDerWaalsContact O-CD2 3.25Å; L207-F211 WeakPolarHBondContact O-CD2 3.41Å; L207-F211 PolarHBondContact O-N 3.03Å; L207-F211 VanDerWaalsContact O-N 3.12Å; G208-F211 PolarHBondContact O-N 2.94Å; F211-F213 VanDerWaalsContact C-N 3.3Å; F211-F213 PolarHBondContact O-N 2.83Å; F211-L214 HydrophobicContact CD1-CD1 4.45Å; F211-L214 PolarHBondContact O-N 2.75Å; F211-V215 WeakPolarHBondContact O-CB 3.46Å; F211-V215 WeakPolarHBondContact O-CG2 3.44Å; F211-V215 PolarHBondContact O-N 3.15Å
212Q89Confident92.7Very high25 Ų2557.5 Ų57.512%0.11730%0.297CS..Hα-helixtrans-60.5-41.5175.6-170.8-75.4-50.400110.8Q194 G208 N209 Y210 L214 V215 G216Q194-Q212 HydrophobicContact CB-CG 4.35Å; Q194-Q212 VanDerWaalsContact N-NE2 3.14Å; G208-Q212 WeakPolarHBondContact O-CB 3.29Å; G208-Q212 PolarHBondContact O-N 3.12Å; N209-Q212 PolarHBondContact O-N 3.27Å; Y210-Q212 VanDerWaalsContact C-N 3.35Å; Y210-Q212 PolarHBondContact O-N 2.92Å; Q212-L214 PolarHBondContact O-N 2.9Å; Q212-V215 PolarHBondContact O-N 3.08Å; Q212-G216 WeakPolarHBondContact O-CA 3.38Å; Q212-G216 PolarHBondContact O-N 3.38Å
213F90.7Very high92.5Very high17 Ų1753.4 Ų53.48%0.07527%0.271CS..Hα-helixtrans-60.2-45175.9-169.6-88.9000112.1D175 T178 I185 N209 Y210 F211 S217D175-F213 HydrophobicContact CB-CD2 3.91Å; D175-F213 HydrophobicContact CB-CE2 3.62Å; D175-F213 HydrophobicContact CB-CZ 3.99Å; D175-F213 WeakPolarHBondContact OD1-CD2 3.35Å; D175-F213 WeakPolarHBondContact OD1-CE2 3.37Å; T178-F213 HydrophobicContact CG2-CE2 4.33Å; T178-F213 HydrophobicContact CG2-CZ 4.07Å; I185-F213 HydrophobicContact CB-CZ 4.37Å; I185-F213 HydrophobicContact CD1-CD1 4.48Å; I185-F213 HydrophobicContact CD1-CE1 3.41Å; I185-F213 VanDerWaalsContact CD1-CE1 3.41Å; I185-F213 HydrophobicContact CD1-CE2 4.09Å; I185-F213 HydrophobicContact CD1-CZ 3.18Å; I185-F213 HydrophobicContact CG1-CE1 4.02Å; I185-F213 HydrophobicContact CG1-CE2 3.81Å; I185-F213 HydrophobicContact CG1-CZ 3.42Å; I185-F213 VanDerWaalsContact CG1-CZ 3.42Å; I185-F213 HydrophobicContact CG2-CD1 4.43Å; I185-F213 HydrophobicContact CG2-CD2 4.07Å; I185-F213 HydrophobicContact CG2-CE1 4.32Å; I185-F213 HydrophobicContact CG2-CE2 3.93Å; I185-F213 HydrophobicContact CG2-CG 4.34Å; I185-F213 HydrophobicContact CG2-CZ 4.1Å; N209-F213 PolarHBondContact O-N 3.47Å; Y210-F213 PolarHBondContact O-N 3.03Å; F211-F213 VanDerWaalsContact C-N 3.3Å; F211-F213 PolarHBondContact O-N 2.83Å; F213-S217 VanDerWaalsContact O-CB 3.26Å; F213-S217 WeakPolarHBondContact O-CB 3.49Å; F213-S217 PolarHBondContact O-N 3.39Å
214L90.1Very high92.4Very high79 Ų7946.3 Ų46.341%0.41424%0.236SC..Hα-helixtrans-63.3-50.2177.9-65.9177.9000112Y210 F211 Q212 Y218Y210-L214 HydrophobicContact CD1-CD1 4.16Å; Y210-L214 HydrophobicContact CE1-CD1 3.56Å; Y210-L214 HydrophobicContact CE1-CG 4.38Å; Y210-L214 PolarHBondContact O-N 3.36Å; F211-L214 HydrophobicContact CD1-CD1 4.45Å; F211-L214 PolarHBondContact O-N 2.75Å; Q212-L214 PolarHBondContact O-N 2.9Å; L214-Y218 WeakPolarHBondContact O-CB 3.25Å; L214-Y218 PolarHBondContact O-N 3.41Å
215V89.2Confident92.5Very high45 Ų4546.6 Ų46.627%0.27323%0.226SC..Hα-helixtrans-66.6-41.5-179.2173.60000110.9M108 F211 Q212 Y218 F219M108-V215 HydrophobicContact CE-CG1 4.26Å; F211-V215 WeakPolarHBondContact O-CB 3.46Å; F211-V215 WeakPolarHBondContact O-CG2 3.44Å; F211-V215 PolarHBondContact O-N 3.15Å; Q212-V215 PolarHBondContact O-N 3.08Å; V215-Y218 PolarHBondContact O-N 3.01Å; V215-F219 WeakPolarHBondContact O-CB 3.19Å; V215-F219 PolarHBondContact O-N 3.41Å
216G88.3Confident92.5Very high0 Ų046.7 Ų46.70%022%0.223CC..Hα-helixtrans-65.2-43.9177.800000112.6Q212 F219 F220Q212-G216 WeakPolarHBondContact O-CA 3.38Å; Q212-G216 PolarHBondContact O-N 3.38Å; G216-F219 PolarHBondContact O-N 3Å; G216-F220 WeakPolarHBondContact O-CD2 3.48Å; G216-F220 PolarHBondContact O-N 3.05Å
217S92.2Very high92.5Very high10 Ų1041.2 Ų41.27%0.0720%0.202CC..Hα-helixtrans-61.6-44.3173.7-177.70000111.3H176 F213 S221H176-S217 WeakPolarHBondContact CA-OG 3.26Å; H176-S217 WeakPolarHBondContact CB-O 3.37Å; F213-S217 VanDerWaalsContact O-CB 3.26Å; F213-S217 WeakPolarHBondContact O-CB 3.49Å; F213-S217 PolarHBondContact O-N 3.39Å; S217-S221 WeakPolarHBondContact O-CB 3.3Å; S217-S221 PolarHBondContact O-N 3.3Å; S217-S221 PolarHBondContact O-OG 2.99Å
218Y91.6Very high92.7Very high130 Ų13037.7 Ų37.751%0.5118%0.183SC..Hα-helixtrans-63.4-43.7177.3-178.2-97.3000112.7M109 L214 V215 F220 S221 L222M109-Y218 HydrophobicContact CE-CD1 3.8Å; M109-Y218 HydrophobicContact CE-CE1 3.64Å; M109-Y218 HydrophobicContact SD-CD1 4.38Å; M109-Y218 HydrophobicContact SD-CE1 3.83Å; L214-Y218 WeakPolarHBondContact O-CB 3.25Å; L214-Y218 PolarHBondContact O-N 3.41Å; V215-Y218 PolarHBondContact O-N 3.01Å; Y218-F220 PolarHBondContact O-N 2.78Å; Y218-S221 WeakPolarHBondContact O-CB 3.45Å; Y218-S221 PolarHBondContact O-N 3.46Å; Y218-L222 PolarHBondContact O-N 2.96Å
219F88.3Confident92.9Very high13 Ų1341.1 Ų41.16%0.05719%0.188CC..Hα-helixtrans-53.1-55.3178.7174.5-78.1000111.7M108 A111 A112 M115 V215 G216 L222 I223M108-F219 WeakPolarHBondContact O-CD2 3.33Å; M108-F219 WeakPolarHBondContact O-CE2 3.48Å; A111-F219 HydrophobicContact CB-CE2 4.23Å; A112-F219 HydrophobicContact CB-CD2 3.24Å; A112-F219 HydrophobicContact CB-CE2 3.39Å; A112-F219 HydrophobicContact CB-CG 3.9Å; A112-F219 HydrophobicContact CB-CZ 4.12Å; A112-F219 VanDerWaalsContact N-CE2 3.26Å; M115-F219 HydrophobicContact SD-CE1 4.14Å; M115-F219 HydrophobicContact SD-CZ 3.76Å; V215-F219 WeakPolarHBondContact O-CB 3.19Å; V215-F219 PolarHBondContact O-N 3.41Å; G216-F219 PolarHBondContact O-N 3Å; F219-L222 WeakPolarHBondContact O-CB 3.46Å; F219-L222 PolarHBondContact O-N 3.08Å; F219-I223 HydrophobicContact CD1-CD1 4.34Å; F219-I223 HydrophobicContact CE1-CD1 3.79Å; F219-I223 HydrophobicContact CZ-CD1 4.45Å
220F88.9Confident93.1Very high19 Ų1941.7 Ų41.78%0.08319%0.193CC..Hα-helixtrans-76.5-28.6-176.9-70.6-67000112.3F149 H176 G216 Y218 L222 I223 G224F149-F220 HydrophobicContact CD2-CD1 4.32Å; F149-F220 AromaticContact CD2-CE1 3.94Å; F149-F220 HydrophobicContact CD2-CE1 3.94Å; F149-F220 HydrophobicContact CE2-CD1 4.22Å; F149-F220 AromaticContact CE2-CE1 3.49Å; F149-F220 HydrophobicContact CE2-CE1 3.49Å; F149-F220 VanDerWaalsContact CE2-CE1 3.49Å; F149-F220 HydrophobicContact CE2-CZ 4.3Å; F149-F220 HydrophobicContact CZ-CE1 4.41Å; H176-F220 HydrophobicContact CB-CB 3.99Å; H176-F220 AromaticContact CE1-CG 3.97Å; H176-F220 VanDerWaalsContact CG-CB 3.46Å; H176-F220 VanDerWaalsContact ND1-CB 3.26Å; H176-F220 WeakPolarHBondContact ND1-CB 3.37Å; H176-F220 AromaticContact ND1-CG 3.86Å; G216-F220 WeakPolarHBondContact O-CD2 3.48Å; G216-F220 PolarHBondContact O-N 3.05Å; Y218-F220 PolarHBondContact O-N 2.78Å; F220-L222 VanDerWaalsContact C-N 3.3Å; F220-L222 PolarHBondContact O-N 3.4Å; F220-I223 HydrophobicContact CD1-CD1 4.1Å; F220-I223 PolarHBondContact O-N 2.84Å; F220-G224 PolarHBondContact O-N 3.15Å
221S95Very high93.3Very high7 Ų736.9 Ų36.95%0.04917%0.174CC..Hα-helixtrans-59.9-40.1171.2-77.50000112.7S217 Y218 G224 D225S217-S221 WeakPolarHBondContact O-CB 3.3Å; S217-S221 PolarHBondContact O-N 3.3Å; S217-S221 PolarHBondContact O-OG 2.99Å; Y218-S221 WeakPolarHBondContact O-CB 3.45Å; Y218-S221 PolarHBondContact O-N 3.46Å; S221-G224 PolarHBondContact O-N 3.16Å; S221-D225 PolarHBondContact O-N 2.82Å
222L93.5Very high93.6Very high29 Ų2936.5 Ų36.515%0.15217%0.172CC..Hα-helixtrans-63-41.3178.8-178.369.1000111.9A112 Q113 Y218 F219 F220 G224 D225 R226A112-L222 HydrophobicContact CB-CD2 4.06Å; Q113-L222 HydrophobicContact CG-CD2 4.34Å; Y218-L222 PolarHBondContact O-N 2.96Å; F219-L222 WeakPolarHBondContact O-CB 3.46Å; F219-L222 PolarHBondContact O-N 3.08Å; F220-L222 VanDerWaalsContact C-N 3.3Å; F220-L222 PolarHBondContact O-N 3.4Å; L222-G224 VanDerWaalsContact C-N 3.31Å; L222-G224 PolarHBondContact O-N 3.37Å; L222-D225 PolarHBondContact O-N 3.22Å; L222-R226 WeakPolarHBondContact O-CG 3.3Å; L222-R226 PolarHBondContact O-N 2.8Å
223I92Very high94Very high1 Ų139.5 Ų39.51%0.00520%0.196CC..Hα-helixtrans-57.7-50.5175.2-63.1172.6000108.9M115 F119 F219 F220 D225 R226 D227M115-I223 HydrophobicContact CB-CD1 3.83Å; M115-I223 HydrophobicContact CB-CG1 4.2Å; M115-I223 HydrophobicContact SD-CD1 4.2Å; F119-I223 HydrophobicContact CB-CG2 3.88Å; F119-I223 HydrophobicContact CD1-CG2 4.06Å; F119-I223 HydrophobicContact CD2-CG2 4.4Å; F119-I223 HydrophobicContact CG-CG2 3.84Å; F219-I223 HydrophobicContact CD1-CD1 4.34Å; F219-I223 HydrophobicContact CE1-CD1 3.79Å; F219-I223 HydrophobicContact CZ-CD1 4.45Å; F220-I223 HydrophobicContact CD1-CD1 4.1Å; F220-I223 PolarHBondContact O-N 2.84Å; I223-D225 VanDerWaalsContact C-N 3.33Å; I223-D225 PolarHBondContact O-N 2.99Å; I223-R226 PolarHBondContact O-N 2.98Å; I223-D227 PolarHBondContact O-N 3Å; I223-D227 VanDerWaalsContact O-N 3.1Å
224G96.1Very high94.3Very high0 Ų041.7 Ų41.70%021%0.21CC..Hα-helixtrans-69.4-28.6-17700000115.2T151 F220 S221 L222 R226 F228 W241T151-G224 WeakPolarHBondContact OG1-CA 3.49Å; T151-G224 PolarHBondContact OG1-O 3.43Å; F220-G224 PolarHBondContact O-N 3.15Å; S221-G224 PolarHBondContact O-N 3.16Å; L222-G224 VanDerWaalsContact C-N 3.31Å; L222-G224 PolarHBondContact O-N 3.37Å; G224-R226 VanDerWaalsContact C-N 3.35Å; G224-F228 PolarHBondContact O-N 3.18Å; G224-F228 VanDerWaalsContact O-N 3.15Å; G224-W241 VanDerWaalsContact C-CD1 3.4Å; G224-W241 VanDerWaalsContact C-NE1 3.26Å; G224-W241 PolarHBondContact O-NE1 3.29Å
225D97Very high94.6Very high58 Ų5839 Ų3931%0.3120%0.197SC..Hα-helixtrans-65.3-39172.2-79.8-31.4000113S221 L222 I223 F228 E229 R242S221-D225 PolarHBondContact O-N 2.82Å; L222-D225 PolarHBondContact O-N 3.22Å; I223-D225 VanDerWaalsContact C-N 3.33Å; I223-D225 PolarHBondContact O-N 2.99Å; D225-F228 PolarHBondContact O-N 3.33Å; D225-E229 PolarHBondContact O-N 3.26Å; D225-R242 IonicContact OD1-CZ 3.93Å; D225-R242 IonicContact OD1-NH1 2.62Å; D225-R242 PolarHBondContact OD1-NH1 3.16Å; D225-R242 IonicContact OD1-NH2 3.65Å; D225-R242 IonicContact OD2-CZ 3.93Å; D225-R242 IonicContact OD2-NH1 3.55Å; D225-R242 PolarHBondContact OD2-NH1 2.85Å; D225-R242 IonicContact OD2-NH2 3.33Å; D225-R242 PolarHBondContact OD2-NH2 3.39Å
226R96.7Very high94.9Very high75 Ų7542.9 Ų42.928%0.28322%0.223SC..Hα-helixtrans-72.1-38.2178.4-68.2-177.1171.4-166.73.3112.2Q113 G116 T117 A120 L222 I223 G224 F228 E229 A230Q113-R226 PolarHBondContact O-NH1 2.92Å; G116-R226 WeakPolarHBondContact O-CD 3.42Å; T117-R226 VanDerWaalsContact N-NH1 3.19Å; T117-R226 PolarHBondContact OG1-NH1 2.93Å; A120-R226 HydrophobicContact CB-CB 3.89Å; L222-R226 WeakPolarHBondContact O-CG 3.3Å; L222-R226 PolarHBondContact O-N 2.8Å; I223-R226 PolarHBondContact O-N 2.98Å; G224-R226 VanDerWaalsContact C-N 3.35Å; R226-F228 VanDerWaalsContact C-N 3.29Å; R226-F228 PolarHBondContact O-N 2.72Å; R226-E229 PolarHBondContact O-N 3.14Å; R226-A230 VanDerWaalsContact O-CB 3.24Å; R226-A230 WeakPolarHBondContact O-CB 3.49Å; R226-A230 PolarHBondContact O-N 2.88Å
227D97.1Very high95.4Very high0 Ų043.3 Ų43.30%023%0.225CC..Hα-helixtrans-55.3-47170.5-75.4-24.6000111.4F119 A120 T151 C152 I223 A230 A231F119-D227 WeakPolarHBondContact CB-OD1 3.32Å; A120-D227 PolarHBondContact N-OD1 2.94Å; T151-D227 PolarHBondContact N-OD2 3.26Å; T151-D227 VanDerWaalsContact OG1-CB 3.27Å; T151-D227 WeakPolarHBondContact OG1-CB 3.22Å; T151-D227 PolarHBondContact OG1-OD2 2.85Å; C152-D227 HydrophobicContact CB-CB 4.43Å; C152-D227 PolarHBondContact N-OD2 3.39Å; I223-D227 PolarHBondContact O-N 3Å; I223-D227 VanDerWaalsContact O-N 3.1Å; D227-A230 PolarHBondContact O-N 3.44Å; D227-A231 WeakPolarHBondContact O-CB 3.31Å; D227-A231 PolarHBondContact O-N 3.4Å
228F98.1Very high95.6Very high28 Ų2848.3 Ų48.312%0.12326%0.256CS..Hα-helixtrans-65-45.3-179.2174.6-114.3000112G224 D225 R226 A230 A231 K232 I237 R239G224-F228 PolarHBondContact O-N 3.18Å; G224-F228 VanDerWaalsContact O-N 3.15Å; D225-F228 PolarHBondContact O-N 3.33Å; R226-F228 VanDerWaalsContact C-N 3.29Å; R226-F228 PolarHBondContact O-N 2.72Å; F228-A230 VanDerWaalsContact C-N 3.35Å; F228-A231 PolarHBondContact O-N 3.24Å; F228-K232 HydrophobicContact CE1-CD 4.15Å; F228-K232 HydrophobicContact CZ-CD 4.03Å; F228-K232 WeakPolarHBondContact O-CB 3.49Å; F228-K232 PolarHBondContact O-N 3.49Å; F228-I237 HydrophobicContact CD2-CD1 4.02Å; F228-I237 HydrophobicContact CE2-CD1 4Å; F228-I237 HydrophobicContact CE2-CG1 4.16Å; F228-R239 VanDerWaalsContact CE2-O 3.31Å; F228-R239 WeakPolarHBondContact CE2-O 3.46Å
229E98.2Very high95.9Very high114 Ų11445.7 Ų45.753%0.53325%0.245SC..Hα-helixtrans-64.3-41.3178.6-168.859.6-153.800111.5D225 R226 K232 S233D225-E229 PolarHBondContact O-N 3.26Å; R226-E229 PolarHBondContact O-N 3.14Å; E229-K232 PolarHBondContact O-N 3.46Å; E229-S233 PolarHBondContact O-N 2.89Å; E229-S233 VanDerWaalsContact O-N 3.17Å
230A97.7Very high96.3Very high13 Ų1346.2 Ų46.211%0.10725%0.25CS..Hα-helixtrans-57.7-53.4172.900000111.9A120 T124 R226 D227 F228 K232 S233A120-A230 HydrophobicContact CB-CB 3.94Å; A120-A230 VanDerWaalsContact O-CB 3.31Å; A120-A230 WeakPolarHBondContact O-CB 3.26Å; T124-A230 WeakPolarHBondContact OG1-CB 3.29Å; R226-A230 VanDerWaalsContact O-CB 3.24Å; R226-A230 WeakPolarHBondContact O-CB 3.49Å; R226-A230 PolarHBondContact O-N 2.88Å; D227-A230 PolarHBondContact O-N 3.44Å; F228-A230 VanDerWaalsContact C-N 3.35Å; A230-K232 PolarHBondContact O-N 3.46Å; A230-S233 WeakPolarHBondContact O-CB 3.22Å; A230-S233 PolarHBondContact O-N 2.96Å; A230-S233 PolarHBondContact O-OG 2.99Å
231A98.3Very high96.7Very high0 Ų045.5 Ų45.50%025%0.247CC..Hα-helixtrans-62.1-43.5-179.700000112.5I127 A155 D227 F228 S233 V234 V235 I237I127-A231 HydrophobicContact CG1-CB 3.92Å; A155-A231 HydrophobicContact CB-CB 3.47Å; A155-A231 VanDerWaalsContact CB-CB 3.47Å; D227-A231 WeakPolarHBondContact O-CB 3.31Å; D227-A231 PolarHBondContact O-N 3.4Å; F228-A231 PolarHBondContact O-N 3.24Å; A231-S233 PolarHBondContact O-N 2.92Å; A231-V234 PolarHBondContact O-N 2.98Å; A231-V235 WeakPolarHBondContact O-CG1 3.5Å; A231-V235 PolarHBondContact O-N 3.33Å; A231-I237 HydrophobicContact CB-CD1 3.75Å
232K97.8Very high96.8Very high103 Ų10349 Ų4945%0.44826%0.259SS..Hα-helixtrans-61.4-27.3179-177.1-177.6173.7-165.30112.9F228 E229 A230 V234 I237F228-K232 HydrophobicContact CE1-CD 4.15Å; F228-K232 HydrophobicContact CZ-CD 4.03Å; F228-K232 WeakPolarHBondContact O-CB 3.49Å; F228-K232 PolarHBondContact O-N 3.49Å; E229-K232 PolarHBondContact O-N 3.46Å; A230-K232 PolarHBondContact O-N 3.46Å; K232-V234 PolarHBondContact O-N 2.81Å; K232-I237 HydrophobicContact CB-CG1 4.26Å
233S97.4Very high97Very high89 Ų8949.6 Ų49.662%0.62227%0.269SS*.Hα-helixtrans-69.9-18.4174.680.50000113.7E229 A230 A231E229-S233 PolarHBondContact O-N 2.89Å; E229-S233 VanDerWaalsContact O-N 3.17Å; A230-S233 WeakPolarHBondContact O-CB 3.22Å; A230-S233 PolarHBondContact O-N 2.96Å; A230-S233 PolarHBondContact O-OG 2.99Å; A231-S233 PolarHBondContact O-N 2.92Å
234V97.2Very high97.3Very high62 Ų6249.8 Ų49.838%0.37627%0.27SS..Hα-helixtrans-107.7-40-176.1-176.60000112.2T124 I127 A231 K232T124-V234 HydrophobicContact CG2-CG2 3.96Å; I127-V234 HydrophobicContact CB-CB 4.49Å; I127-V234 HydrophobicContact CB-CG1 4.46Å; I127-V234 HydrophobicContact CG2-CB 3.79Å; I127-V234 HydrophobicContact CG2-CG1 3.77Å; A231-V234 PolarHBondContact O-N 2.98Å; K232-V234 PolarHBondContact O-N 2.81Å
235V97Very high97.4Very high24 Ų2449.8 Ų49.815%0.14527%0.27CS..SBendtrans-129.6143.4-175.167.70000110.4I127 L133 A159 A231 I237I127-V235 HydrophobicContact CG2-CB 3.9Å; I127-V235 HydrophobicContact CG2-CG1 3.5Å; I127-V235 VanDerWaalsContact CG2-CG1 3.5Å; L133-V235 HydrophobicContact CD1-CB 4.49Å; L133-V235 HydrophobicContact CD1-CG2 4.13Å; A159-V235 HydrophobicContact CB-CG1 4.17Å; A159-V235 HydrophobicContact CB-CG2 4.02Å; A231-V235 WeakPolarHBondContact O-CG1 3.5Å; A231-V235 PolarHBondContact O-N 3.33Å; V235-I237 HydrophobicContact CG1-CD1 4.36Å; V235-I237 HydrophobicContact CG1-CG1 4.12Å; V235-I237 HydrophobicContact CG1-CG2 3.84Å; V235-I237 PolarHBondContact O-N 2.85Å
236P95.4Very high97.4Very high126 Ų12647.6 Ų47.682%0.81826%0.258SS*.  trans-77.758.2-173.633.3-39000113.3
237I97.5Very high97.4Very high8 Ų846.9 Ų46.94%0.04126%0.258CS..  trans-85149.9171.958.9170.6000110.8A155 E158 A159 F228 A231 K232 V235A155-I237 HydrophobicContact CB-CD1 3.65Å; E158-I237 HydrophobicContact CB-CB 4.37Å; E158-I237 HydrophobicContact CB-CG2 3.87Å; E158-I237 HydrophobicContact CG-CB 3.79Å; E158-I237 HydrophobicContact CG-CG2 3.55Å; A159-I237 HydrophobicContact CB-CG2 4.08Å; F228-I237 HydrophobicContact CD2-CD1 4.02Å; F228-I237 HydrophobicContact CE2-CD1 4Å; F228-I237 HydrophobicContact CE2-CG1 4.16Å; A231-I237 HydrophobicContact CB-CD1 3.75Å; K232-I237 HydrophobicContact CB-CG1 4.26Å; V235-I237 HydrophobicContact CG1-CD1 4.36Å; V235-I237 HydrophobicContact CG1-CG1 4.12Å; V235-I237 HydrophobicContact CG1-CG2 3.84Å; V235-I237 PolarHBondContact O-N 2.85Å
238T96.6Very high97.5Very high115 Ų11546.9 Ų46.971%0.70626%0.258SS*.  trans-123.2-27-176.757.90000113.8
239R97.7Very high97.5Very high75 Ų7545.5 Ų45.528%0.28325%0.252SS..  trans-91.9125.5-180-60.5-171-68.6162.13.1110.2E158 F228 A243 I244 E247E158-R239 VanDerWaalsContact CD-NE 3.33Å; E158-R239 IonicContact OE1-CZ 3.69Å; E158-R239 IonicContact OE1-NE 3.94Å; E158-R239 PolarHBondContact OE1-NE 3.28Å; E158-R239 IonicContact OE1-NH2 2.87Å; E158-R239 IonicContact OE2-CZ 3.65Å; E158-R239 IonicContact OE2-NE 2.85Å; E158-R239 PolarHBondContact OE2-NE 3.42Å; E158-R239 VanDerWaalsContact OE2-NE 3.09Å; E158-R239 IonicContact OE2-NH2 2.8Å; E158-R239 PolarHBondContact OE2-NH2 3.45Å; F228-R239 VanDerWaalsContact CE2-O 3.31Å; F228-R239 WeakPolarHBondContact CE2-O 3.46Å; R239-A243 HydrophobicContact CB-CB 4.19Å; R239-I244 HydrophobicContact CB-CD1 4.14Å; R239-I244 HydrophobicContact CB-CG1 3.96Å; R239-I244 WeakPolarHBondContact O-CD1 3.48Å; R239-E247 IonicContact CZ-OE2 2.61Å; R239-E247 IonicContact NH1-OE1 3.58Å; R239-E247 PolarHBondContact NH1-OE1 3.39Å; R239-E247 IonicContact NH1-OE2 2.84Å; R239-E247 PolarHBondContact NH1-OE2 3.22Å
240S97.4Very high97.5Very high25 Ų2540.6 Ų40.618%0.17523%0.229CC..  trans-80.3170.617471.60000111.5R242 A243 I244S240-R242 PolarHBondContact O-N 3.31Å; S240-R242 VanDerWaalsContact O-N 3.08Å; S240-R242 PolarHBondContact OG-N 3.31Å; S240-A243 PolarHBondContact O-N 2.84Å; S240-I244 WeakPolarHBondContact O-CG1 3.25Å; S240-I244 PolarHBondContact O-N 3.17Å; S240-I244 VanDerWaalsContact O-N 3.11Å
241W97.6Very high97.6Very high4 Ų440 Ų402%0.01522%0.224CC..Hα-helixtrans-53.1-30.5173.772-90.9000112.6T151 Y154 H176 V180 G224 A243 I244 L245T151-W241 HydrophobicContact CG2-CB 4.21Å; T151-W241 HydrophobicContact CG2-CD2 4.13Å; T151-W241 HydrophobicContact CG2-CE3 4.5Å; T151-W241 HydrophobicContact CG2-CG 3.99Å; Y154-W241 HydrophobicContact CD2-CB 3.84Å; Y154-W241 HydrophobicContact CG-CB 4.27Å; H176-W241 HydrophobicContact CB-CH2 4.14Å; H176-W241 AromaticContact CD2-CH2 3.67Å; H176-W241 AromaticContact CD2-CZ3 3.77Å; V180-W241 HydrophobicContact CB-CH2 4.35Å; V180-W241 HydrophobicContact CB-CZ3 3.92Å; V180-W241 HydrophobicContact CG1-CE3 4.41Å; V180-W241 HydrophobicContact CG1-CZ3 4.01Å; V180-W241 HydrophobicContact CG2-CH2 3.51Å; V180-W241 HydrophobicContact CG2-CZ2 4.46Å; V180-W241 HydrophobicContact CG2-CZ3 3.56Å; G224-W241 VanDerWaalsContact C-CD1 3.4Å; G224-W241 VanDerWaalsContact C-NE1 3.26Å; G224-W241 PolarHBondContact O-NE1 3.29Å; W241-A243 VanDerWaalsContact C-N 3.27Å; W241-A243 PolarHBondContact O-N 2.96Å; W241-I244 PolarHBondContact O-N 3.12Å; W241-L245 HydrophobicContact CE3-CD2 3.98Å; W241-L245 HydrophobicContact CZ3-CD2 3.95Å; W241-L245 WeakPolarHBondContact O-CB 3.36Å; W241-L245 PolarHBondContact O-N 2.93Å
242R97.1Very high97.6Very high80 Ų8040 Ų4030%0.30222%0.224SC..Hα-helixtrans-65.4-28.1177.2-65.7-158.4-178.975.4-0.5114.2V180 D225 S240 P246V180-R242 HydrophobicContact CG1-CB 4.32Å; V180-R242 HydrophobicContact CG2-CB 4.46Å; V180-R242 HydrophobicContact CG2-CG 3.93Å; D225-R242 IonicContact OD1-CZ 3.93Å; D225-R242 IonicContact OD1-NH1 2.62Å; D225-R242 PolarHBondContact OD1-NH1 3.16Å; D225-R242 IonicContact OD1-NH2 3.65Å; D225-R242 IonicContact OD2-CZ 3.93Å; D225-R242 IonicContact OD2-NH1 3.55Å; D225-R242 PolarHBondContact OD2-NH1 2.85Å; D225-R242 IonicContact OD2-NH2 3.33Å; D225-R242 PolarHBondContact OD2-NH2 3.39Å; S240-R242 PolarHBondContact O-N 3.31Å; S240-R242 VanDerWaalsContact O-N 3.08Å; S240-R242 PolarHBondContact OG-N 3.31Å; R242-P246 WeakPolarHBondContact O-CD 3.32Å; R242-P246 VanDerWaalsContact O-CG 3.24Å; R242-P246 WeakPolarHBondContact O-CG 3.33Å
243A97Very high97.6Very high42 Ų4235.3 Ų35.335%0.34720%0.204SC..Hα-helixtrans-87.5-35.4174.700000111.4R239 S240 W241R239-A243 HydrophobicContact CB-CB 4.19Å; S240-A243 PolarHBondContact O-N 2.84Å; W241-A243 VanDerWaalsContact C-N 3.27Å; W241-A243 PolarHBondContact O-N 2.96Å
244I98.1Very high97.5Very high5 Ų531.5 Ų31.53%0.02618%0.177CC..Hα-helixtrans-81.6-47.6-172.9-59.9168.8000112Y154 E158 H165 R239 S240 W241 E247Y154-I244 HydrophobicContact CD1-CB 4.29Å; Y154-I244 HydrophobicContact CD1-CG2 3.67Å; Y154-I244 HydrophobicContact CG-CG2 4.29Å; Y154-I244 WeakPolarHBondContact O-CD1 3.46Å; E158-I244 HydrophobicContact CB-CD1 3.85Å; E158-I244 HydrophobicContact CG-CD1 4.42Å; H165-I244 PolarHBondContact CE1-O 3.21Å; H165-I244 PolarHBondContact NE2-O 3.42Å; R239-I244 HydrophobicContact CB-CD1 4.14Å; R239-I244 HydrophobicContact CB-CG1 3.96Å; R239-I244 WeakPolarHBondContact O-CD1 3.48Å; S240-I244 WeakPolarHBondContact O-CG1 3.25Å; S240-I244 PolarHBondContact O-N 3.17Å; S240-I244 VanDerWaalsContact O-N 3.11Å; W241-I244 PolarHBondContact O-N 3.12Å; I244-E247 WeakPolarHBondContact O-CA 3.23Å; I244-E247 VanDerWaalsContact O-CB 3.28Å; I244-E247 WeakPolarHBondContact O-CB 3.43Å; I244-E247 PolarHBondContact O-N 3.33Å
245L98Very high97.4Very high0 Ų030 Ų300%017%0.166CC..G310 helixtrans-53.5-42.9-177.7166.966.5000113.3P148 Y154 A167 V177 V180 I181 W241 E247 A248 I251P148-L245 HydrophobicContact CB-CD1 4.25Å; P148-L245 HydrophobicContact CB-CD2 4.29Å; Y154-L245 HydrophobicContact CE1-CB 4.28Å; Y154-L245 HydrophobicContact CE1-CD1 4.37Å; Y154-L245 HydrophobicContact CE2-CB 4.37Å; Y154-L245 HydrophobicContact CE2-CD1 4.48Å; Y154-L245 VanDerWaalsContact OH-CD1 3.28Å; Y154-L245 WeakPolarHBondContact OH-CD1 3.26Å; A167-L245 HydrophobicContact CB-CD1 3.98Å; V177-L245 HydrophobicContact CB-CD2 4.37Å; V177-L245 HydrophobicContact CG1-CD2 4.23Å; V177-L245 HydrophobicContact CG2-CD2 4.05Å; V180-L245 HydrophobicContact CB-CD2 4.45Å; V180-L245 HydrophobicContact CG1-CD2 4.07Å; I181-L245 HydrophobicContact CG2-CD2 4.41Å; I181-L245 HydrophobicContact CG2-CG 4.11Å; W241-L245 HydrophobicContact CE3-CD2 3.98Å; W241-L245 HydrophobicContact CZ3-CD2 3.95Å; W241-L245 WeakPolarHBondContact O-CB 3.36Å; W241-L245 PolarHBondContact O-N 2.93Å; L245-E247 PolarHBondContact O-N 2.89Å; L245-A248 WeakPolarHBondContact O-CB 3.21Å; L245-A248 PolarHBondContact O-N 2.98Å; L245-A248 VanDerWaalsContact O-N 3.09Å; L245-I251 HydrophobicContact CD1-CD1 3.87Å
246P97.5Very high97.4Very high11 Ų1129 Ų297%0.07116%0.159CC..G310 helixtrans-59-26.1172.6-29.338.7000115.2V180 R242 A248 K268 R483V180-P246 HydrophobicContact CG1-CG 3.8Å; V180-P246 WeakPolarHBondContact O-CG 3.32Å; R242-P246 WeakPolarHBondContact O-CD 3.32Å; R242-P246 VanDerWaalsContact O-CG 3.24Å; R242-P246 WeakPolarHBondContact O-CG 3.33Å; P246-A248 PolarHBondContact O-N 3.03Å; P246-K268 PolarHBondContact O-NZ 2.97Å; P246-R483 VanDerWaalsContact CB-NH1 3.32Å; P246-R483 VanDerWaalsContact CG-NH1 3.33Å
247E97.6Very high97.4Very high60 Ų6026.5 Ų26.528%0.2814%0.143SC..G310 helixtrans-79.5-6.3178.3-61.4179.1177.400112.6R239 I244 L245 S249 K474R239-E247 IonicContact CZ-OE2 2.61Å; R239-E247 IonicContact NH1-OE1 3.58Å; R239-E247 PolarHBondContact NH1-OE1 3.39Å; R239-E247 IonicContact NH1-OE2 2.84Å; R239-E247 PolarHBondContact NH1-OE2 3.22Å; I244-E247 WeakPolarHBondContact O-CA 3.23Å; I244-E247 VanDerWaalsContact O-CB 3.28Å; I244-E247 WeakPolarHBondContact O-CB 3.43Å; I244-E247 PolarHBondContact O-N 3.33Å; L245-E247 PolarHBondContact O-N 2.89Å; E247-S249 PolarHBondContact O-N 2.99Å; E247-K474 HydrophobicContact CB-CD 4.21Å; E247-K474 WeakPolarHBondContact OE2-CE 3.44Å; E247-K474 IonicContact OE2-NZ 3.91Å; E247-K474 PolarHBondContact OE2-NZ 2.57Å
248A98.4Very high97.3Very high0 Ų029.9 Ų29.90%016%0.161CC..  trans-52.9140.7172.700000110H165 L245 P246 F250 I251 K268H165-A248 WeakPolarHBondContact NE2-CA 3.41Å; H165-A248 WeakPolarHBondContact NE2-CB 3.16Å; H165-A248 PolarHBondContact NE2-N 2.93Å; H165-A248 WeakPolarHBondContact O-CA 3.15Å; L245-A248 WeakPolarHBondContact O-CB 3.21Å; L245-A248 PolarHBondContact O-N 2.98Å; L245-A248 VanDerWaalsContact O-N 3.09Å; P246-A248 PolarHBondContact O-N 3.03Å; A248-F250 VanDerWaalsContact C-N 3.33Å; A248-I251 HydrophobicContact CB-CD1 3.82Å; A248-K268 WeakPolarHBondContact O-CE 3.39Å; A248-K268 PolarHBondContact O-NZ 3.29Å
249S98.5Very high97.4Very high0 Ų024.5 Ų24.50%013%0.128CC..SBendtrans-67.7-41.3179.6-45.10000110.4H165 E247 G473H165-S249 PolarHBondContact O-N 3.01Å; H165-S249 PolarHBondContact O-OG 3.37Å; E247-S249 PolarHBondContact O-N 2.99Å; S249-G473 PolarHBondContact OG-O 3.17Å
250F98.6Very high97.3Very high10 Ų1021.3 Ų21.34%0.04412%0.116CC..  trans-143.6153.5177.2-58-71.6000110.8V166 A167 A248 L252 K268 V270 Y465 F468 A469 L475 L478V166-F250 HydrophobicContact CG1-CB 4.36Å; V166-F250 HydrophobicContact CG1-CD2 4.43Å; A167-F250 PolarHBondContact N-O 2.95Å; A167-F250 VanDerWaalsContact N-O 3.14Å; A248-F250 VanDerWaalsContact C-N 3.33Å; F250-L252 HydrophobicContact CB-CD2 4.21Å; F250-K268 WeakPolarHBondContact CA-O 3.27Å; F250-V270 HydrophobicContact CB-CG2 4.36Å; F250-V270 HydrophobicContact CD1-CG2 3.99Å; F250-V270 HydrophobicContact CG-CG2 4.4Å; F250-Y465 AromaticContact CD1-CD1 3.58Å; F250-Y465 HydrophobicContact CD1-CD1 3.58Å; F250-Y465 AromaticContact CD1-CE1 3.84Å; F250-Y465 HydrophobicContact CD1-CE1 3.84Å; F250-Y465 AromaticContact CD2-CD1 3.72Å; F250-Y465 HydrophobicContact CD2-CD1 3.72Å; F250-Y465 HydrophobicContact CD2-CG 4.45Å; F250-Y465 AromaticContact CE1-CD1 3.52Å; F250-Y465 HydrophobicContact CE1-CD1 3.52Å; F250-Y465 AromaticContact CE1-CE1 3.58Å; F250-Y465 HydrophobicContact CE1-CE1 3.58Å; F250-Y465 AromaticContact CE2-CD1 3.65Å; F250-Y465 HydrophobicContact CE2-CD1 3.65Å; F250-Y465 HydrophobicContact CE2-CE1 4.47Å; F250-Y465 HydrophobicContact CE2-CG 4.49Å; F250-Y465 AromaticContact CG-CD1 3.68Å; F250-Y465 HydrophobicContact CG-CD1 3.68Å; F250-Y465 HydrophobicContact CG-CE1 4.4Å; F250-Y465 AromaticContact CZ-CD1 3.55Å; F250-Y465 HydrophobicContact CZ-CD1 3.55Å; F250-Y465 AromaticContact CZ-CE1 3.92Å; F250-Y465 HydrophobicContact CZ-CE1 3.92Å; F250-F468 HydrophobicContact CE2-CB 4.45Å; F250-F468 AromaticContact CE2-CD1 3.89Å; F250-F468 HydrophobicContact CE2-CD1 3.89Å; F250-F468 AromaticContact CZ-CD1 3.89Å; F250-F468 HydrophobicContact CZ-CD1 3.89Å; F250-F468 HydrophobicContact CZ-CE1 4.34Å; F250-A469 HydrophobicContact CD2-CB 4.17Å; F250-A469 HydrophobicContact CE2-CB 4.3Å; F250-L475 HydrophobicContact CE1-CD1 3.9Å; F250-L475 HydrophobicContact CE2-CD1 3.89Å; F250-L475 HydrophobicContact CZ-CD1 3.42Å; F250-L475 VanDerWaalsContact CZ-CD1 3.42Å; F250-L478 HydrophobicContact CD1-CD1 4.36Å; F250-L478 HydrophobicContact CE1-CD1 3.76Å
251I98.3Very high97.2Very high1 Ų120.1 Ų20.11%0.00511%0.108CC..EExtended strand (participates in β ladder)trans-110.8102.1169.9-50.8-60.8000106.9A167 L169 V177 I181 L245 A248 T253 K268 I269 V270A167-I251 HydrophobicContact CB-CD1 3.7Å; L169-I251 HydrophobicContact CD1-CG2 3.56Å; V177-I251 HydrophobicContact CG1-CG2 4.31Å; I181-I251 HydrophobicContact CD1-CG1 4.12Å; I181-I251 HydrophobicContact CG2-CD1 4.37Å; I181-I251 HydrophobicContact CG2-CG1 4.49Å; L245-I251 HydrophobicContact CD1-CD1 3.87Å; A248-I251 HydrophobicContact CB-CD1 3.82Å; I251-T253 HydrophobicContact CG2-CG2 4.4Å; I251-K268 HydrophobicContact CG1-CD 4.4Å; I251-K268 HydrophobicContact CG1-CG 4.4Å; I251-K268 PolarHBondContact N-O 3.5Å; I251-I269 HydrophobicContact CB-CD1 3.63Å; I251-I269 HydrophobicContact CG1-CD1 4.01Å; I251-I269 HydrophobicContact CG2-CD1 3.94Å; I251-I269 WeakPolarHBondContact O-CA 3.38Å; I251-V270 PolarHBondContact O-N 2.97Å
252L98.5Very high97.1Very high0 Ų024.3 Ų24.30%014%0.136CC..EExtended strand (participates in β ladder)trans-87.5123-178-55.6174.7000109.2V166 A167 I168 L169 F250 V270 I272 L462 V466V166-L252 HydrophobicContact CG2-CD1 4.44Å; A167-L252 WeakPolarHBondContact O-CB 3.15Å; A167-L252 PolarHBondContact O-N 3.44Å; I168-L252 CarbonylContact C-O 3.51Å; I168-L252 WeakPolarHBondContact CA-O 3.16Å; I168-L252 HydrophobicContact CD1-CD1 4.36Å; I168-L252 HydrophobicContact CG1-CB 4.09Å; I168-L252 HydrophobicContact CG1-CD1 3.9Å; L169-L252 PolarHBondContact N-O 2.93Å; F250-L252 HydrophobicContact CB-CD2 4.21Å; L252-V270 CarbonylContact C-O 3.57Å; L252-V270 VanDerWaalsContact CA-O 3.28Å; L252-V270 WeakPolarHBondContact CA-O 3.32Å; L252-V270 HydrophobicContact CD2-CB 3.63Å; L252-V270 HydrophobicContact CD2-CG1 3.89Å; L252-V270 HydrophobicContact CD2-CG2 4.33Å; L252-I272 HydrophobicContact CB-CD1 3.61Å; L252-I272 HydrophobicContact CB-CG1 4Å; L252-I272 HydrophobicContact CD1-CD1 4.32Å; L252-I272 HydrophobicContact CD2-CG2 4.34Å; L252-L462 HydrophobicContact CD1-CD1 3.56Å; L252-V466 HydrophobicContact CD1-CG2 4.07Å
253T97.5Very high96.9Very high5 Ų522.3 Ų22.33%0.03114%0.136CC..EExtended strand (participates in β ladder)trans-111.6146.2-173.664.40000112.3L169 I251 Q255 I269 V270 I272 G273L169-T253 HydrophobicContact CD2-CG2 4.4Å; I251-T253 HydrophobicContact CG2-CG2 4.4Å; T253-Q255 PolarHBondContact O-N 3.16Å; T253-Q255 WeakPolarHBondContact OG1-CB 3.36Å; T253-I269 HydrophobicContact CG2-CG2 3.81Å; T253-V270 PolarHBondContact N-O 3.49Å; T253-I272 VanDerWaalsContact O-CG1 3.24Å; T253-I272 WeakPolarHBondContact O-CG1 3.21Å; T253-I272 PolarHBondContact O-N 3.02Å; T253-G273 PolarHBondContact O-N 2.86Å
254N96.6Very high96.8Very high9 Ų922.2 Ų22.25%0.04813%0.132CC..SBendtrans-7725.8172.3-164.223.3000112.7L169 T170 A171 G273 G274 L378L169-N254 VanDerWaalsContact O-CB 3.3Å; L169-N254 WeakPolarHBondContact O-CB 3.3Å; L169-N254 PolarHBondContact O-N 3.46Å; T170-N254 WeakPolarHBondContact O-CB 3.3Å; T170-N254 PolarHBondContact O-ND2 3.02Å; A171-N254 PolarHBondContact O-N 3.27Å; N254-G273 WeakPolarHBondContact OD1-CA 3.28Å; N254-G274 PolarHBondContact OD1-N 3.49Å; N254-L378 HydrophobicContact CB-CD2 4.17Å
255Q95.2Very high96.6Very high30 Ų3025.9 Ų25.914%0.1416%0.155CC..  trans-83.2142.4176.7-173.9-175.49.900110.5N172 T253 D260 P271 G273N172-Q255 WeakPolarHBondContact OD1-CA 3.38Å; T253-Q255 PolarHBondContact O-N 3.16Å; T253-Q255 WeakPolarHBondContact OG1-CB 3.36Å; Q255-D260 VanDerWaalsContact CD-OD2 3.25Å; Q255-D260 HydrophobicContact CG-CB 3.54Å; Q255-D260 VanDerWaalsContact CG-OD2 3.29Å; Q255-D260 WeakPolarHBondContact CG-OD2 3.25Å; Q255-D260 PolarHBondContact NE2-OD2 3.12Å; Q255-P271 WeakPolarHBondContact O-CB 3.33Å; Q255-G273 VanDerWaalsContact O-CA 3.32Å; Q255-G273 WeakPolarHBondContact O-CA 3.49Å; Q255-G273 PolarHBondContact O-N 3.35Å
256I96.4Very high96.4Very high3 Ų327.6 Ų27.62%0.01516%0.162CC..  trans-111.2112.3162.1-58.4175.5000108.1L258 L259 D260 T382 L451 Q454I256-L258 PolarHBondContact O-N 2.88Å; I256-L258 VanDerWaalsContact O-N 3.14Å; I256-L259 HydrophobicContact CB-CB 3.99Å; I256-L259 HydrophobicContact CG2-CB 4.28Å; I256-L259 WeakPolarHBondContact O-CA 3.4Å; I256-L259 WeakPolarHBondContact O-CB 3.5Å; I256-L259 PolarHBondContact O-N 3.34Å; I256-D260 PolarHBondContact O-N 3.1Å; I256-T382 HydrophobicContact CD1-CG2 3.67Å; I256-L451 HydrophobicContact CG2-CD2 3.56Å; I256-Q454 VanDerWaalsContact CG2-OE1 3.23Å
257P95.7Very high96.3Very high73 Ų7333.6 Ų33.647%0.47419%0.194SC..THydrogen-bonded Turntrans-57.5-31.5-173-3037.1000115.3L259 P271P257-L259 VanDerWaalsContact C-N 3.26Å; P257-L259 PolarHBondContact O-N 3.36Å; P257-P271 HydrophobicContact CG-CB 3.78Å; P257-P271 HydrophobicContact CG-CG 3.65Å
258L95.9Very high96.3Very high79 Ų7931 Ų3141%0.41418%0.181SC..THydrogen-bonded Turntrans-75.6-14.1176.4-65.6-178.7000113.5I256 H410 M450 L451 Q454I256-L258 PolarHBondContact O-N 2.88Å; I256-L258 VanDerWaalsContact O-N 3.14Å; L258-H410 PolarHBondContact O-CE1 3.3Å; L258-M450 HydrophobicContact CD1-CB 4.35Å; L258-L451 HydrophobicContact CB-CD2 3.91Å; L258-Q454 HydrophobicContact CD1-CG 3.99Å
259L96.9Very high96.2Very high3 Ų331.5 Ų31.52%0.01618%0.184CC..THydrogen-bonded Turntrans-100.7-43.1176.9178.654.2000111.5I256 P257 V381 A385 M406 L407 H410 L447 L451I256-L259 HydrophobicContact CB-CB 3.99Å; I256-L259 HydrophobicContact CG2-CB 4.28Å; I256-L259 WeakPolarHBondContact O-CA 3.4Å; I256-L259 WeakPolarHBondContact O-CB 3.5Å; I256-L259 PolarHBondContact O-N 3.34Å; P257-L259 VanDerWaalsContact C-N 3.26Å; P257-L259 PolarHBondContact O-N 3.36Å; L259-V381 HydrophobicContact CD2-CG1 4.4Å; L259-A385 HydrophobicContact CD1-CB 4.17Å; L259-A385 HydrophobicContact CD2-CB 4.12Å; L259-M406 HydrophobicContact CD1-CE 4.36Å; L259-M406 HydrophobicContact CD2-CE 3.95Å; L259-M406 HydrophobicContact CG-CE 3.81Å; L259-M406 HydrophobicContact CG-CG 4.46Å; L259-M406 HydrophobicContact CG-SD 4.12Å; L259-M406 WeakPolarHBondContact O-CG 3.44Å; L259-L407 HydrophobicContact CD1-CD1 4.23Å; L259-H410 PolarHBondContact O-NE2 3.42Å; L259-L447 HydrophobicContact CD1-CD1 4.47Å; L259-L447 HydrophobicContact CD1-CD2 3.92Å; L259-L451 HydrophobicContact CB-CD2 4.07Å; L259-L451 HydrophobicContact CD2-CD1 4.45Å
260D96.3Very high96.2Very high7 Ų731.8 Ų31.84%0.03719%0.186CC..SBendtrans-76.6170.5-171.9-160.719.8000113.6Q255 I256 R402 M406Q255-D260 VanDerWaalsContact CD-OD2 3.25Å; Q255-D260 HydrophobicContact CG-CB 3.54Å; Q255-D260 VanDerWaalsContact CG-OD2 3.29Å; Q255-D260 WeakPolarHBondContact CG-OD2 3.25Å; Q255-D260 PolarHBondContact NE2-OD2 3.12Å; I256-D260 PolarHBondContact O-N 3.1Å; D260-R402 VanDerWaalsContact CG-NH2 3.3Å; D260-R402 IonicContact OD1-CZ 2.95Å; D260-R402 VanDerWaalsContact OD1-CZ 3.28Å; D260-R402 IonicContact OD1-NH1 3.4Å; D260-R402 PolarHBondContact OD1-NH1 3.37Å; D260-R402 IonicContact OD1-NH2 3.96Å; D260-R402 PolarHBondContact OD1-NH2 3.4Å; D260-R402 IonicContact OD2-CZ 2.73Å; D260-R402 IonicContact OD2-NH1 3.57Å; D260-R402 IonicContact OD2-NH2 3.76Å; D260-R402 PolarHBondContact OD2-NH2 3.35Å; D260-M406 HydrophobicContact CB-SD 3.95Å
261F96Very high96.1Very high1 Ų133.4 Ų33.40%0.00420%0.197CC..PPolyproline II helixtrans-65.4131.3172.3-60.7-75.1000110.8P191 D199 A263 R402 Q405 M406P191-F261 HydrophobicContact CG-CD2 4.09Å; P191-F261 HydrophobicContact CG-CE1 4.4Å; P191-F261 HydrophobicContact CG-CE2 3.82Å; P191-F261 HydrophobicContact CG-CG 4.47Å; P191-F261 HydrophobicContact CG-CZ 3.97Å; D199-F261 HydrophobicContact CB-CD1 3.77Å; D199-F261 HydrophobicContact CB-CE1 4.13Å; F261-A263 PolarHBondContact O-N 2.86Å; F261-R402 HydrophobicContact CE2-CG 4.2Å; F261-Q405 HydrophobicContact CZ-CB 3.94Å; F261-M406 HydrophobicContact CD2-CB 4.26Å; F261-M406 HydrophobicContact CE2-CB 3.66Å; F261-M406 HydrophobicContact CE2-CG 4.38Å; F261-M406 VanDerWaalsContact CZ-CA 3.45Å; F261-M406 HydrophobicContact CZ-CB 4.02Å; F261-M406 VanDerWaalsContact CZ-N 3.33Å
262P94.8Very high96.1Very high92 Ų9233.5 Ų33.560%0.59720%0.198SC*.PPolyproline II helixtrans-57.2125.8167.3-23.834.4000110
263A94.1Very high96Very high37 Ų3733.8 Ų33.831%0.30620%0.2SC..  trans-143.9152.4-177.500000110.4V190 F261 T265V190-A263 HydrophobicContact CG1-CB 4.02Å; V190-A263 HydrophobicContact CG2-CB 3.69Å; F261-A263 PolarHBondContact O-N 2.86Å; A263-T265 PolarHBondContact O-N 3.18Å
264P94.4Very high95.7Very high40 Ų4033.9 Ų33.926%0.2620%0.203SC..  trans-56.9136.3168.2-25.336.8000111.3P184 A186 Y189P184-P264 HydrophobicContact CB-CB 3.88Å; A186-P264 HydrophobicContact CB-CG 4.02Å; Y189-P264 WeakPolarHBondContact OH-CD 3.44Å; Y189-P264 WeakPolarHBondContact OH-CG 3.47Å
265T94.2Very high95.6Very high82 Ų8234 Ų3450%0.50320%0.203SC..  trans-151.2176-180-165.30000109.5A263 I269A263-T265 PolarHBondContact O-N 3.18Å; T265-I269 WeakPolarHBondContact OG1-CB 3.1Å
266F94Very high95.2Very high37 Ų3733.6 Ų33.616%0.16220%0.204CC..  trans-142.9164.2173.452.9-108.3000110.9I181 Q183 K268 I269 N480I181-F266 HydrophobicContact CD1-CZ 4.32Å; I181-F266 HydrophobicContact CG1-CZ 4.09Å; Q183-F266 VanDerWaalsContact CA-CE1 3.45Å; Q183-F266 HydrophobicContact CB-CE1 3.98Å; Q183-F266 HydrophobicContact CB-CZ 4.4Å; F266-K268 HydrophobicContact CD2-CB 3.48Å; F266-K268 VanDerWaalsContact CD2-CB 3.48Å; F266-K268 HydrophobicContact CE2-CB 3.4Å; F266-K268 HydrophobicContact CE2-CD 3.9Å; F266-K268 HydrophobicContact CE2-CG 4.25Å; F266-K268 PolarHBondContact O-N 2.97Å; F266-I269 HydrophobicContact CD2-CG1 4.43Å; F266-I269 HydrophobicContact CE2-CG1 4.4Å; F266-I269 WeakPolarHBondContact O-CB 3.37Å; F266-I269 PolarHBondContact O-N 2.55Å; F266-N480 HydrophobicContact CD1-CB 4.44Å; F266-N480 HydrophobicContact CE1-CB 3.96Å; F266-N480 HydrophobicContact CZ-CB 4.15Å
267D95.3Very high94.7Very high136 Ų13633.9 Ų33.973%0.72721%0.206SC*.THydrogen-bonded Turntrans-61.9-12.3-165-61.3-33.9000116I269D267-I269 VanDerWaalsContact C-N 3.32Å
268K96.3Very high94.2Very high5 Ų536 Ų362%0.02221%0.208CC..THydrogen-bonded Turntrans-71.4-27.2171.4-163.1-177.6-176.3126.50112.6P246 A248 F250 I251 F266 L478P246-K268 PolarHBondContact O-NZ 2.97Å; A248-K268 WeakPolarHBondContact O-CE 3.39Å; A248-K268 PolarHBondContact O-NZ 3.29Å; F250-K268 WeakPolarHBondContact CA-O 3.27Å; I251-K268 HydrophobicContact CG1-CD 4.4Å; I251-K268 HydrophobicContact CG1-CG 4.4Å; I251-K268 PolarHBondContact N-O 3.5Å; F266-K268 HydrophobicContact CD2-CB 3.48Å; F266-K268 VanDerWaalsContact CD2-CB 3.48Å; F266-K268 HydrophobicContact CE2-CB 3.4Å; F266-K268 HydrophobicContact CE2-CD 3.9Å; F266-K268 HydrophobicContact CE2-CG 4.25Å; F266-K268 PolarHBondContact O-N 2.97Å; K268-L478 HydrophobicContact CB-CB 4.38Å; K268-L478 HydrophobicContact CG-CB 4.49Å
269I97.2Very high93.4Very high11 Ų1135.2 Ų35.26%0.05621%0.206CC..EExtended strand (participates in β ladder)trans-85.9116.6178.2-53.9-57.6000108.4I181 I251 T253 T265 F266 D267I181-I269 HydrophobicContact CD1-CD1 3.45Å; I181-I269 VanDerWaalsContact CD1-CD1 3.45Å; I251-I269 HydrophobicContact CB-CD1 3.63Å; I251-I269 HydrophobicContact CG1-CD1 4.01Å; I251-I269 HydrophobicContact CG2-CD1 3.94Å; I251-I269 WeakPolarHBondContact O-CA 3.38Å; T253-I269 HydrophobicContact CG2-CG2 3.81Å; T265-I269 WeakPolarHBondContact OG1-CB 3.1Å; F266-I269 HydrophobicContact CD2-CG1 4.43Å; F266-I269 HydrophobicContact CE2-CG1 4.4Å; F266-I269 WeakPolarHBondContact O-CB 3.37Å; F266-I269 PolarHBondContact O-N 2.55Å; D267-I269 VanDerWaalsContact C-N 3.32Å
270V97.8Very high92.8Very high6 Ų639.8 Ų39.84%0.03623%0.227CC..EExtended strand (participates in β ladder)trans-122.3108.8-172.6-1790000109.4F250 I251 L252 T253 I272 T461 Y465F250-V270 HydrophobicContact CB-CG2 4.36Å; F250-V270 HydrophobicContact CD1-CG2 3.99Å; F250-V270 HydrophobicContact CG-CG2 4.4Å; I251-V270 PolarHBondContact O-N 2.97Å; L252-V270 CarbonylContact C-O 3.57Å; L252-V270 VanDerWaalsContact CA-O 3.28Å; L252-V270 WeakPolarHBondContact CA-O 3.32Å; L252-V270 HydrophobicContact CD2-CB 3.63Å; L252-V270 HydrophobicContact CD2-CG1 3.89Å; L252-V270 HydrophobicContact CD2-CG2 4.33Å; T253-V270 PolarHBondContact N-O 3.49Å; V270-I272 HydrophobicContact CG1-CG2 4.49Å; V270-I272 PolarHBondContact O-N 2.98Å; V270-T461 HydrophobicContact CG1-CG2 3.49Å; V270-T461 VanDerWaalsContact CG1-CG2 3.49Å; V270-Y465 HydrophobicContact CB-CD1 4.48Å; V270-Y465 HydrophobicContact CB-CE1 4.41Å; V270-Y465 HydrophobicContact CG1-CD1 4.22Å; V270-Y465 HydrophobicContact CG1-CD2 3.78Å; V270-Y465 HydrophobicContact CG1-CE1 4.15Å; V270-Y465 HydrophobicContact CG1-CE2 3.69Å; V270-Y465 HydrophobicContact CG1-CG 4.03Å; V270-Y465 HydrophobicContact CG2-CD1 3.65Å; V270-Y465 HydrophobicContact CG2-CE1 3.38Å; V270-Y465 HydrophobicContact CG2-CE2 4.43Å; V270-Y465 HydrophobicContact CG2-CG 4.28Å
271P97.3Very high92Very high45 Ų4544.3 Ų44.329%0.29225%0.247SC..EExtended strand (participates in β ladder)trans-68.4127178.5-19.432.2000111.8Q255 P257Q255-P271 WeakPolarHBondContact O-CB 3.33Å; P257-P271 HydrophobicContact CG-CB 3.78Å; P257-P271 HydrophobicContact CG-CG 3.65Å
272I97.5Very high91.3Very high3 Ų351.6 Ų51.62%0.01528%0.278CS..  trans-128.220.2175.456.9162.5000111.3I168 L252 T253 V270 L275 T461 L462I168-I272 HydrophobicContact CG2-CD1 4.29Å; L252-I272 HydrophobicContact CB-CD1 3.61Å; L252-I272 HydrophobicContact CB-CG1 4Å; L252-I272 HydrophobicContact CD1-CD1 4.32Å; L252-I272 HydrophobicContact CD2-CG2 4.34Å; T253-I272 VanDerWaalsContact O-CG1 3.24Å; T253-I272 WeakPolarHBondContact O-CG1 3.21Å; T253-I272 PolarHBondContact O-N 3.02Å; V270-I272 HydrophobicContact CG1-CG2 4.49Å; V270-I272 PolarHBondContact O-N 2.98Å; I272-L275 HydrophobicContact CB-CD1 4.46Å; I272-L275 HydrophobicContact CB-CG 4.49Å; I272-L275 HydrophobicContact CD1-CD1 3.8Å; I272-L275 HydrophobicContact CG1-CD1 4.47Å; I272-L275 VanDerWaalsContact O-CG 3.25Å; I272-L275 WeakPolarHBondContact O-CG 3.28Å; I272-T461 HydrophobicContact CG2-CG2 3.97Å; I272-L462 HydrophobicContact CD1-CD1 4.27Å; I272-L462 HydrophobicContact CG2-CB 4.33Å
273G95.7Very high90.9Very high5 Ų552.3 Ų52.35%0.05228%0.277CS..THydrogen-bonded Turntrans-54.6142.5-175.200000114.2T253 N254 Q255T253-G273 PolarHBondContact O-N 2.86Å; N254-G273 WeakPolarHBondContact OD1-CA 3.28Å; Q255-G273 VanDerWaalsContact O-CA 3.32Å; Q255-G273 WeakPolarHBondContact O-CA 3.49Å; Q255-G273 PolarHBondContact O-N 3.35Å
274G92.6Very high90.7Very high8 Ų851.3 Ų51.38%0.08227%0.266CS..THydrogen-bonded Turntrans93.17.517700000116.1N254 S276 V277N254-G274 PolarHBondContact OD1-N 3.49Å; G274-S276 PolarHBondContact O-N 2.98Å; G274-V277 PolarHBondContact O-N 3.25Å; G274-V277 VanDerWaalsContact O-N 3.13Å
275L93.2Very high90.5Very high10 Ų1057.9 Ų57.95%0.05229%0.291CS..THydrogen-bonded Turntrans-54.5-38.2178.7-63.3-172.4000114.1A39 A40 I43 I272 P458 K459 L462A39-L275 HydrophobicContact CB-CB 4.41Å; A40-L275 HydrophobicContact CB-CD1 4.37Å; I43-L275 HydrophobicContact CD1-CB 4.07Å; I43-L275 HydrophobicContact CD1-CD1 4.14Å; I43-L275 HydrophobicContact CD1-CD2 3.91Å; I43-L275 HydrophobicContact CD1-CG 4.26Å; I272-L275 HydrophobicContact CB-CD1 4.46Å; I272-L275 HydrophobicContact CB-CG 4.49Å; I272-L275 HydrophobicContact CD1-CD1 3.8Å; I272-L275 HydrophobicContact CG1-CD1 4.47Å; I272-L275 VanDerWaalsContact O-CG 3.25Å; I272-L275 WeakPolarHBondContact O-CG 3.28Å; L275-P458 HydrophobicContact CD2-CB 3.8Å; L275-P458 HydrophobicContact CD2-CG 4.3Å; L275-K459 HydrophobicContact CD2-CG 4.09Å; L275-L462 HydrophobicContact CD1-CD2 3.69Å
276S86.6Confident90.4Very high22 Ų2255.3 Ų55.315%0.15427%0.274CS..THydrogen-bonded Turntrans-88.1-4.8-175.467.20000113.7G274G274-S276 PolarHBondContact O-N 2.98Å
277V87.8Confident90.4Very high10 Ų1057.2 Ų57.26%0.06129%0.286CS..  trans-88.5125.4179.6-179.80000109.5G274 T279 T382 E383 M386G274-V277 PolarHBondContact O-N 3.25Å; G274-V277 VanDerWaalsContact O-N 3.13Å; V277-T279 HydrophobicContact CG1-CG2 4.14Å; V277-T279 PolarHBondContact O-N 2.88Å; V277-T382 HydrophobicContact CG2-CG2 3.7Å; V277-E383 HydrophobicContact CB-CG 4.43Å; V277-E383 HydrophobicContact CG1-CG 3.98Å; V277-E383 HydrophobicContact CG2-CG 3.8Å; V277-M386 HydrophobicContact CB-SD 4.15Å; V277-M386 HydrophobicContact CG1-SD 3.86Å
278K84.5Confident90.5Very high118 Ų11858.9 Ų58.951%0.51329%0.289SS..  trans-81.8113.5170.4-54.4174.4-176.9172.30107.8L284 N361 M387K278-L284 HydrophobicContact CB-CD2 4.13Å; K278-L284 HydrophobicContact CD-CD2 4.12Å; K278-N361 PolarHBondContact O-ND2 3.33Å; K278-M387 WeakPolarHBondContact O-CE 3.39Å
279T78.6Confident90.5Very high62 Ų6264.6 Ų64.638%0.3831%0.314SS..  trans-97.5-18.2-174.553.60000113.7V277 K281 M386V277-T279 HydrophobicContact CG1-CG2 4.14Å; V277-T279 PolarHBondContact O-N 2.88Å; T279-K281 PolarHBondContact O-N 3.22Å; T279-M386 HydrophobicContact CG2-CE 3.28Å; T279-M386 HydrophobicContact CG2-SD 3.72Å
280E84.1Confident90.5Very high99 Ų9964.6 Ų64.646%0.46331%0.314SS..  trans-70.887.4179.2-69.9-172.7-145.800111.3K282 N283E280-K282 HydrophobicContact CB-CG 4.35Å; E280-K282 PolarHBondContact O-N 3.43Å; E280-K282 WeakPolarHBondContact OE2-CE 3.22Å; E280-K282 IonicContact OE2-NZ 3.63Å; E280-K282 PolarHBondContact OE2-NZ 2.99Å; E280-N283 HydrophobicContact CB-CB 4.4Å; E280-N283 PolarHBondContact O-N 2.88Å; E280-N283 PolarHBondContact OE2-ND2 2.82Å
281K79.2Confident90.4Very high101 Ų10166.3 Ų66.344%0.43933%0.326SS..G310 helixtrans-49.8-35.8179.7-65.6-171176.2-169.20113.2T279 N283 L284 M387T279-K281 PolarHBondContact O-N 3.22Å; K281-N283 PolarHBondContact O-N 2.78Å; K281-N283 VanDerWaalsContact O-N 3.15Å; K281-L284 PolarHBondContact O-N 3.42Å; K281-M387 HydrophobicContact CD-SD 4.32Å; K281-M387 VanDerWaalsContact CE-SD 3.6Å; K281-M387 HydrophobicContact CG-SD 3.95Å; K281-M387 PolarHBondContact NZ-O 2.59Å
282K81.6Confident90.5Very high155 Ų15571.7 Ų71.767%0.67435%0.345SS*.G310 helixtrans-58.2-26.3176.962.1173-173.9-175.30114.2E280E280-K282 HydrophobicContact CB-CG 4.35Å; E280-K282 PolarHBondContact O-N 3.43Å; E280-K282 WeakPolarHBondContact OE2-CE 3.22Å; E280-K282 IonicContact OE2-NZ 3.63Å; E280-K282 PolarHBondContact OE2-NZ 2.99Å
283N87.8Confident90.5Very high107 Ų10772.2 Ų72.257%0.57235%0.347SS*.G310 helixtrans-95.5-6.9179.8-58.4-20.5000112.1E280 K281 K285E280-N283 HydrophobicContact CB-CB 4.4Å; E280-N283 PolarHBondContact O-N 2.88Å; E280-N283 PolarHBondContact OE2-ND2 2.82Å; K281-N283 PolarHBondContact O-N 2.78Å; K281-N283 VanDerWaalsContact O-N 3.15Å; N283-K285 PolarHBondContact O-N 3.02Å
284L89.1Confident90.6Very high15 Ų1572.1 Ų72.18%0.07935%0.345CS..  trans-95.678.5179.3-61.2179000109.1K278 K281 N361 E362 A365 M387K278-L284 HydrophobicContact CB-CD2 4.13Å; K278-L284 HydrophobicContact CD-CD2 4.12Å; K281-L284 PolarHBondContact O-N 3.42Å; L284-N361 WeakPolarHBondContact CD1-ND2 3.24Å; L284-N361 WeakPolarHBondContact CD2-ND2 3.37Å; L284-E362 HydrophobicContact CB-CG 4.22Å; L284-E362 HydrophobicContact CD2-CG 4.41Å; L284-A365 HydrophobicContact CB-CB 4.01Å; L284-A365 HydrophobicContact CD1-CB 3.77Å; L284-M387 HydrophobicContact CD1-CE 3.97Å; L284-M387 HydrophobicContact CD1-SD 4.26Å
285K89.4Confident90.9Very high179 Ų17974.2 Ų74.278%0.77837%0.367SS*.PPolyproline II helixtrans-95.3120.5175.9-66.6-172.1-179.5-178.20109.8N283N283-K285 PolarHBondContact O-N 3.02Å
286L92.9Very high91.1Very high27 Ų2778.4 Ų78.414%0.14139%0.389CS..PPolyproline II helixtrans-67.9140172.4-166.164.2000110W290 L294 P359 E362 L363L286-W290 HydrophobicContact CD1-CB 3.64Å; L286-W290 HydrophobicContact CD1-CG 4.27Å; L286-W290 HydrophobicContact CD2-CB 3.67Å; L286-W290 HydrophobicContact CG-CB 3.61Å; L286-L294 HydrophobicContact CD2-CD1 3.46Å; L286-L294 VanDerWaalsContact CD2-CD1 3.46Å; L286-L294 HydrophobicContact CD2-CG 4.26Å; L286-P359 HydrophobicContact CD1-CB 4.35Å; L286-P359 HydrophobicContact CD1-CG 3.66Å; L286-E362 HydrophobicContact CB-CB 4.43Å; L286-E362 HydrophobicContact CD1-CB 3.9Å; L286-L363 HydrophobicContact CD1-CD2 3.88Å; L286-L363 HydrophobicContact CD1-CG 4.02Å; L286-L363 HydrophobicContact CD2-CD2 4.02Å
287D94.1Very high91.6Very high77 Ų7779.3 Ų79.341%0.41239%0.389SS..PPolyproline II helixtrans-65162.6175.168.244.9000112K289 W290 S291D287-K289 PolarHBondContact O-N 3.33Å; D287-K289 WeakPolarHBondContact OD1-CB 3.3Å; D287-K289 PolarHBondContact OD1-N 3.4Å; D287-K289 VanDerWaalsContact OD1-N 3.15Å; D287-W290 PolarHBondContact O-N 3.43Å; D287-W290 PolarHBondContact OD1-N 3.16Å; D287-S291 VanDerWaalsContact O-CB 3.3Å; D287-S291 WeakPolarHBondContact O-CB 3.48Å; D287-S291 PolarHBondContact O-N 3.29Å
288E96.2Very high92Very high172 Ų17287.3 Ų87.380%0.80442%0.423SS*.Hα-helixtrans-60.1-35.4-174.9-170.6179175.700112.4K292E288-K292 VanDerWaalsContact O-CB 3.32Å; E288-K292 WeakPolarHBondContact O-CB 3.46Å; E288-K292 PolarHBondContact O-N 3.43Å
289K96.8Very high92.7Very high124 Ų12483.3 Ų83.354%0.53941%0.407SS..Hα-helixtrans-61.1-56.2179.8174.3-170.4172.3-173.40110.4D287 K292 I293D287-K289 PolarHBondContact O-N 3.33Å; D287-K289 WeakPolarHBondContact OD1-CB 3.3Å; D287-K289 PolarHBondContact OD1-N 3.4Å; D287-K289 VanDerWaalsContact OD1-N 3.15Å; K289-K292 PolarHBondContact O-N 3.48Å; K289-I293 HydrophobicContact CG-CD1 4.11Å; K289-I293 WeakPolarHBondContact O-CG1 3.27Å; K289-I293 PolarHBondContact O-N 2.87Å; K289-I293 VanDerWaalsContact O-N 3.1Å
290W97Very high93.6Very high12 Ų1280.5 Ų80.55%0.04539%0.39CS..Hα-helixtrans-72.1-33.9-177-60.3114.6000111.8L286 D287 K292 I293 L294 I335 H353 L358 P359 L363L286-W290 HydrophobicContact CD1-CB 3.64Å; L286-W290 HydrophobicContact CD1-CG 4.27Å; L286-W290 HydrophobicContact CD2-CB 3.67Å; L286-W290 HydrophobicContact CG-CB 3.61Å; D287-W290 PolarHBondContact O-N 3.43Å; D287-W290 PolarHBondContact OD1-N 3.16Å; W290-K292 VanDerWaalsContact C-N 3.3Å; W290-K292 PolarHBondContact O-N 3.32Å; W290-I293 HydrophobicContact CD2-CD1 4.41Å; W290-I293 HydrophobicContact CE3-CD1 3.56Å; W290-I293 HydrophobicContact CZ3-CD1 3.7Å; W290-I293 PolarHBondContact O-N 2.63Å; W290-L294 WeakPolarHBondContact O-CG 3.39Å; W290-L294 PolarHBondContact O-N 2.86Å; W290-I335 HydrophobicContact CE3-CD1 3.99Å; W290-I335 HydrophobicContact CE3-CG1 4.33Å; W290-I335 HydrophobicContact CE3-CG2 4.13Å; W290-I335 HydrophobicContact CH2-CG2 4.39Å; W290-I335 HydrophobicContact CZ3-CD1 4.46Å; W290-I335 HydrophobicContact CZ3-CG1 4.31Å; W290-I335 HydrophobicContact CZ3-CG2 3.76Å; W290-H353 HydrophobicContact CZ3-CB 3.99Å; W290-L358 HydrophobicContact CH2-CD2 3.29Å; W290-L358 HydrophobicContact CZ2-CD2 3.11Å; W290-L358 HydrophobicContact CZ3-CD2 4.1Å; W290-P359 VanDerWaalsContact CD1-CG 3.49Å; W290-P359 HydrophobicContact CG-CG 4.25Å; W290-L363 HydrophobicContact CB-CD2 4.44Å
291S97.4Very high94.3Very high42 Ų4275.9 Ų75.929%0.29437%0.368SS..Hα-helixtrans-61.7-39174.4-171.90000112.2D287 G295 R368D287-S291 VanDerWaalsContact O-CB 3.3Å; D287-S291 WeakPolarHBondContact O-CB 3.48Å; D287-S291 PolarHBondContact O-N 3.29Å; S291-G295 PolarHBondContact O-N 2.71Å; S291-R368 PolarHBondContact O-NH1 3.47Å; S291-R368 PolarHBondContact OG-NH2 2.93Å
292K97.9Very high95.2Very high158 Ų15871.1 Ų71.169%0.68735%0.347SS*.Hα-helixtrans-65.2-45.8173-177.8175.8179.11790111.5E288 K289 W290 L294 G295 I296E288-K292 VanDerWaalsContact O-CB 3.32Å; E288-K292 WeakPolarHBondContact O-CB 3.46Å; E288-K292 PolarHBondContact O-N 3.43Å; K289-K292 PolarHBondContact O-N 3.48Å; W290-K292 VanDerWaalsContact C-N 3.3Å; W290-K292 PolarHBondContact O-N 3.32Å; K292-L294 VanDerWaalsContact C-N 3.34Å; K292-L294 PolarHBondContact O-N 3.47Å; K292-G295 PolarHBondContact O-N 3.24Å; K292-I296 WeakPolarHBondContact O-CG1 3.41Å
293I98Very high96Very high14 Ų1463.8 Ų63.87%0.07232%0.316CS..Hα-helixtrans-56.9-46178-73.9167.3000111.4K289 W290 G295 I296 T333 I335 H353K289-I293 HydrophobicContact CG-CD1 4.11Å; K289-I293 WeakPolarHBondContact O-CG1 3.27Å; K289-I293 PolarHBondContact O-N 2.87Å; K289-I293 VanDerWaalsContact O-N 3.1Å; W290-I293 HydrophobicContact CD2-CD1 4.41Å; W290-I293 HydrophobicContact CE3-CD1 3.56Å; W290-I293 HydrophobicContact CZ3-CD1 3.7Å; W290-I293 PolarHBondContact O-N 2.63Å; I293-G295 PolarHBondContact O-N 3.44Å; I293-G295 VanDerWaalsContact O-N 3.17Å; I293-I296 PolarHBondContact O-N 2.79Å; I293-T333 HydrophobicContact CG2-CG2 3.58Å; I293-I335 HydrophobicContact CG2-CD1 4.04Å; I293-I335 HydrophobicContact CG2-CG1 4.08Å; I293-H353 HydrophobicContact CD1-CB 4.24Å; I293-H353 WeakPolarHBondContact CG2-CD2 3.29Å
294L97.9Very high96.5Very high2 Ų259 Ų591%0.0129%0.29CS..THydrogen-bonded Turntrans-65.1-16.6177.5-68.7-176.8000113.9L286 W290 K292 N300 I335 L363 D366 R368L286-L294 HydrophobicContact CD2-CD1 3.46Å; L286-L294 VanDerWaalsContact CD2-CD1 3.46Å; L286-L294 HydrophobicContact CD2-CG 4.26Å; W290-L294 WeakPolarHBondContact O-CG 3.39Å; W290-L294 PolarHBondContact O-N 2.86Å; K292-L294 VanDerWaalsContact C-N 3.34Å; K292-L294 PolarHBondContact O-N 3.47Å; L294-N300 WeakPolarHBondContact CA-OD1 3.37Å; L294-N300 HydrophobicContact CD2-CB 3.55Å; L294-N300 VanDerWaalsContact CD2-CG 3.45Å; L294-N300 PolarHBondContact O-ND2 2.86Å; L294-N300 VanDerWaalsContact O-ND2 3.15Å; L294-I335 HydrophobicContact CD2-CD1 3.76Å; L294-I335 HydrophobicContact CG-CD1 4.41Å; L294-L363 HydrophobicContact CD1-CD2 4.1Å; L294-L363 HydrophobicContact CD2-CD2 4.48Å; L294-L363 HydrophobicContact CG-CD2 4.48Å; L294-D366 HydrophobicContact CD1-CB 3.95Å; L294-R368 HydrophobicContact CB-CB 4.34Å
295G97.8Very high96.9Very high53 Ų5358.3 Ų58.355%0.54629%0.287SS..THydrogen-bonded Turntrans-91.4-6.2179.300000115.1S291 K292 I293S291-G295 PolarHBondContact O-N 2.71Å; K292-G295 PolarHBondContact O-N 3.24Å; I293-G295 PolarHBondContact O-N 3.44Å; I293-G295 VanDerWaalsContact O-N 3.17Å
296I97.9Very high96.9Very high97 Ų9750.5 Ų50.550%0.49726%0.257SS..THydrogen-bonded Turntrans-76.2-43.1-174.3-59.2174.8000111.6K292 I293K292-I296 WeakPolarHBondContact O-CG1 3.41Å; I293-I296 PolarHBondContact O-N 2.79Å
297R98Very high96.4Very high41 Ų4151.7 Ų51.716%0.15527%0.267CS..SBendtrans-126.2165.6-171-58.3-175.717579.1-0111.4P330 D331 T333 D350R297-P330 WeakPolarHBondContact CD-O 3.03Å; R297-P330 PolarHBondContact NE-O 3.27Å; R297-D331 WeakPolarHBondContact CB-O 3.1Å; R297-T333 WeakPolarHBondContact CB-OG1 3.35Å; R297-T333 WeakPolarHBondContact CD-OG1 2.94Å; R297-T333 WeakPolarHBondContact CG-OG1 3.49Å; R297-D350 PolarHBondContact NH1-O 3.44Å; R297-D350 VanDerWaalsContact NH2-CG 3.28Å; R297-D350 PolarHBondContact NH2-O 3.01Å; R297-D350 VanDerWaalsContact NH2-O 3.16Å; R297-D350 IonicContact NH2-OD1 2.72Å; R297-D350 PolarHBondContact NH2-OD1 3.19Å; R297-D350 IonicContact NH2-OD2 3.73Å; R297-D350 PolarHBondContact NH2-OD2 2.82Å
298K95.7Very high96Very high179 Ų17950.7 Ų50.778%0.77826%0.262SS*.SBendtrans-68.7-44.3-176.3-177.9-179175.9-178.30112.6
299N98.4Very high95.8Very high34 Ų3442.6 Ų42.618%0.18222%0.224CC..EExtended strand (participates in β ladder)trans-109.7144.8-177.4-48.4-53.6000109.9D331 T332 T333 S370 I435N299-D331 PolarHBondContact N-O 2.6Å; N299-T332 HydrophobicContact CB-CG2 3.86Å; N299-T332 WeakPolarHBondContact O-CA 3.42Å; N299-T333 PolarHBondContact O-N 3.43Å; N299-S370 WeakPolarHBondContact CA-OG 3.36Å; N299-I435 HydrophobicContact CB-CD1 4.45Å; N299-I435 HydrophobicContact CB-CG2 4.38Å
300N98.7Very high95.6Very high3 Ų341.2 Ų41.22%0.01622%0.219CC..EExtended strand (participates in β ladder)trans-131125.7177.5-61.2-76000109.8L294 T333 R368 L369 S370 V371L294-N300 WeakPolarHBondContact CA-OD1 3.37Å; L294-N300 HydrophobicContact CD2-CB 3.55Å; L294-N300 VanDerWaalsContact CD2-CG 3.45Å; L294-N300 PolarHBondContact O-ND2 2.86Å; L294-N300 VanDerWaalsContact O-ND2 3.15Å; N300-T333 CarbonylContact C-O 3.59Å; N300-T333 WeakPolarHBondContact CA-O 3.43Å; N300-T333 VanDerWaalsContact OD1-CB 3.31Å; N300-T333 WeakPolarHBondContact OD1-CB 3.34Å; N300-R368 PolarHBondContact ND2-O 3.2Å; N300-L369 HydrophobicContact CB-CD1 4.34Å; N300-S370 PolarHBondContact N-OG 3Å; N300-S370 WeakPolarHBondContact O-CA 3.28Å; N300-S370 VanDerWaalsContact O-CB 3.26Å; N300-S370 WeakPolarHBondContact O-CB 3.49Å; N300-S370 PolarHBondContact O-N 3.35Å; N300-S370 PolarHBondContact O-OG 3.35Å; N300-V371 PolarHBondContact O-N 3.33Å
301V98.8Very high95.5Very high1 Ų140.7 Ų40.71%0.00622%0.216CC..EExtended strand (participates in β ladder)trans-115.2124.8177.6177.90000108.2I303 T332 T333 F334 I335 V371 V373 L431 I435V301-I303 HydrophobicContact CG1-CD1 4.44Å; V301-I303 HydrophobicContact CG1-CG1 3.93Å; V301-T332 HydrophobicContact CB-CG2 4.42Å; V301-T332 HydrophobicContact CG2-CG2 3.65Å; V301-T333 PolarHBondContact N-O 2.97Å; V301-F334 HydrophobicContact CB-CD1 3.68Å; V301-F334 HydrophobicContact CB-CE1 3.9Å; V301-F334 HydrophobicContact CG1-CD1 3.97Å; V301-F334 HydrophobicContact CG1-CE1 4.18Å; V301-F334 HydrophobicContact CG2-CD1 4.26Å; V301-F334 HydrophobicContact CG2-CE1 3.97Å; V301-F334 CarbonylContact O-C 3.55Å; V301-F334 WeakPolarHBondContact O-CA 2.97Å; V301-I335 PolarHBondContact O-N 3.43Å; V301-V371 WeakPolarHBondContact CA-O 3.43Å; V301-V373 HydrophobicContact CG1-CG2 3.75Å; V301-L431 HydrophobicContact CG1-CD2 4.17Å; V301-L431 HydrophobicContact CG2-CD2 4.44Å; V301-I435 HydrophobicContact CG2-CD1 4.06Å
302F98.8Very high95.4Very high1 Ų140.5 Ų40.50%0.00421%0.213CC..EExtended strand (participates in β ladder)trans-98.2137170.4176.3-137.2000108.6I335 L358 Q360 L363 L369 V371 F372 V373F302-I335 CarbonylContact C-O 3.55Å; F302-I335 WeakPolarHBondContact CA-O 3.41Å; F302-I335 HydrophobicContact CD2-CB 4.25Å; F302-I335 HydrophobicContact CD2-CG2 4Å; F302-I335 WeakPolarHBondContact CD2-O 3.35Å; F302-I335 HydrophobicContact CE2-CG2 4.45Å; F302-L358 HydrophobicContact CD2-CD1 4.35Å; F302-L358 HydrophobicContact CE2-CB 4.27Å; F302-L358 HydrophobicContact CE2-CD1 3.55Å; F302-L358 HydrophobicContact CZ-CB 4.45Å; F302-L358 HydrophobicContact CZ-CD1 4.41Å; F302-Q360 HydrophobicContact CE1-CB 3.84Å; F302-Q360 HydrophobicContact CE1-CG 3.71Å; F302-Q360 HydrophobicContact CZ-CB 4.03Å; F302-Q360 HydrophobicContact CZ-CG 4.33Å; F302-L363 HydrophobicContact CD1-CD1 4.43Å; F302-L363 HydrophobicContact CD2-CD1 3.94Å; F302-L363 HydrophobicContact CE2-CD1 4.07Å; F302-L363 HydrophobicContact CG-CD1 4.17Å; F302-L363 HydrophobicContact CZ-CD1 4.34Å; F302-L369 HydrophobicContact CB-CD1 3.65Å; F302-L369 HydrophobicContact CB-CD2 4.21Å; F302-V371 PolarHBondContact N-O 3.14Å; F302-F372 HydrophobicContact CB-CD2 4.12Å; F302-F372 AromaticContact CD1-CD2 3.33Å; F302-F372 HydrophobicContact CD1-CD2 3.33Å; F302-F372 AromaticContact CD1-CE2 3.26Å; F302-F372 HydrophobicContact CD1-CE2 3.26Å; F302-F372 HydrophobicContact CD1-CG 4.1Å; F302-F372 AromaticContact CD1-CZ 3.95Å; F302-F372 HydrophobicContact CD1-CZ 3.95Å; F302-F372 AromaticContact CE1-CD2 3.89Å; F302-F372 HydrophobicContact CE1-CD2 3.89Å; F302-F372 HydrophobicContact CE1-CE1 4.47Å; F302-F372 AromaticContact CE1-CE2 3.29Å; F302-F372 HydrophobicContact CE1-CE2 3.29Å; F302-F372 AromaticContact CE1-CZ 3.63Å; F302-F372 HydrophobicContact CE1-CZ 3.63Å; F302-F372 AromaticContact CG-CD2 3.91Å; F302-F372 HydrophobicContact CG-CD2 3.91Å; F302-F372 HydrophobicContact CG-CE2 4.02Å; F302-F372 HydrophobicContact CZ-CE2 4.07Å; F302-F372 HydrophobicContact CZ-CZ 4.48Å; F302-F372 CarbonylContact O-C 3.4Å; F302-F372 WeakPolarHBondContact O-CA 3.32Å; F302-F372 WeakPolarHBondContact O-CD2 3.26Å; F302-V373 PolarHBondContact O-N 2.98Å
303I98.6Very high95.2Very high2 Ų235.7 Ų35.71%0.0120%0.196CC..EExtended strand (participates in β ladder)trans-127.1121.2-179.3-51.2178.8000108.3V301 F305 F326 F334 I335 W336 K337 V373V301-I303 HydrophobicContact CG1-CD1 4.44Å; V301-I303 HydrophobicContact CG1-CG1 3.93Å; I303-F305 HydrophobicContact CG2-CD2 4.23Å; I303-F305 HydrophobicContact CG2-CE2 3.56Å; I303-F305 HydrophobicContact CG2-CZ 4.24Å; I303-F326 HydrophobicContact CD1-CE1 3.64Å; I303-F326 HydrophobicContact CD1-CZ 3.59Å; I303-F334 HydrophobicContact CD1-CD1 4.17Å; I303-I335 PolarHBondContact N-O 3.3Å; I303-W336 HydrophobicContact CB-CB 4.24Å; I303-W336 HydrophobicContact CB-CG 4.03Å; I303-W336 VanDerWaalsContact CG2-CD1 3.49Å; I303-W336 HydrophobicContact CG2-CG 4.17Å; I303-K337 PolarHBondContact O-N 3Å; I303-V373 WeakPolarHBondContact CA-O 3.21Å; I303-V373 HydrophobicContact CB-CB 4.33Å; I303-V373 HydrophobicContact CG1-CB 4.03Å; I303-V373 HydrophobicContact CG1-CG2 4.15Å; I303-V373 HydrophobicContact CG2-CB 4.15Å; I303-V373 HydrophobicContact CG2-CG1 4.28Å
304S97.9Very high95.1Very high5 Ų535.2 Ų35.24%0.03519%0.193CC..EExtended strand (participates in β ladder)trans-152.2121.3175.2177.20000111.9G306 V373 T374S304-G306 VanDerWaalsContact C-N 3.27Å; S304-G306 PolarHBondContact OG-N 3.16Å; S304-V373 PolarHBondContact N-O 3.17Å; S304-T374 VanDerWaalsContact O-CA 3.25Å; S304-T374 WeakPolarHBondContact O-CA 2.87Å; S304-T374 VanDerWaalsContact O-CB 3.3Å; S304-T374 WeakPolarHBondContact O-CB 3.17Å; S304-T374 PolarHBondContact O-OG1 3.21Å
305F95.9Very high94.9Very high1 Ų136.3 Ų36.30%0.00420%0.2CC..  trans-94.722.5173.1-59.1-88.2000112.2W98 I303 A309 M314 V373 H375 I394 L396W98-F305 HydrophobicContact CH2-CB 3.96Å; W98-F305 AromaticContact CH2-CD1 3.45Å; W98-F305 HydrophobicContact CH2-CD1 3.45Å; W98-F305 VanDerWaalsContact CH2-CD1 3.45Å; W98-F305 AromaticContact CH2-CD2 3.65Å; W98-F305 HydrophobicContact CH2-CD2 3.65Å; W98-F305 AromaticContact CH2-CE1 3.71Å; W98-F305 HydrophobicContact CH2-CE1 3.71Å; W98-F305 AromaticContact CH2-CE2 3.9Å; W98-F305 HydrophobicContact CH2-CE2 3.9Å; W98-F305 AromaticContact CH2-CG 3.4Å; W98-F305 HydrophobicContact CH2-CG 3.4Å; W98-F305 VanDerWaalsContact CH2-CG 3.4Å; W98-F305 AromaticContact CH2-CZ 3.94Å; W98-F305 HydrophobicContact CH2-CZ 3.94Å; W98-F305 HydrophobicContact CZ2-CB 3.87Å; W98-F305 HydrophobicContact CZ2-CD1 4.23Å; W98-F305 HydrophobicContact CZ2-CD2 4.11Å; W98-F305 AromaticContact CZ2-CG 3.82Å; W98-F305 HydrophobicContact CZ2-CG 3.82Å; W98-F305 HydrophobicContact CZ3-CD1 4.22Å; W98-F305 HydrophobicContact CZ3-CE1 4.18Å; W98-F305 HydrophobicContact CZ3-CZ 4.47Å; I303-F305 HydrophobicContact CG2-CD2 4.23Å; I303-F305 HydrophobicContact CG2-CE2 3.56Å; I303-F305 HydrophobicContact CG2-CZ 4.24Å; F305-A309 HydrophobicContact CB-CB 4.14Å; F305-A309 WeakPolarHBondContact CB-O 3.28Å; F305-A309 WeakPolarHBondContact O-CB 3.45Å; F305-M314 HydrophobicContact CD2-CE 4.32Å; F305-M314 HydrophobicContact CE2-CE 3.77Å; F305-M314 HydrophobicContact CZ-CE 4.16Å; F305-V373 HydrophobicContact CZ-CG1 4.34Å; F305-H375 WeakPolarHBondContact CA-ND1 3.49Å; F305-H375 HydrophobicContact CD1-CB 4.02Å; F305-H375 PolarHBondContact O-CE1 2.8Å; F305-H375 PolarHBondContact O-ND1 3.37Å; F305-I394 HydrophobicContact CE1-CB 4.07Å; F305-I394 HydrophobicContact CE1-CD1 4.04Å; F305-I394 HydrophobicContact CE1-CG1 4.39Å; F305-I394 HydrophobicContact CZ-CD1 4.09Å; F305-L396 HydrophobicContact CD1-CD1 4.24Å
306G90.6Very high94.8Very high15 Ų1538.5 Ų38.516%0.15520%0.199CC..THydrogen-bonded Turntrans81.4-166.8173.800000113.8S304 K337 H375S304-G306 VanDerWaalsContact C-N 3.27Å; S304-G306 PolarHBondContact OG-N 3.16Å; G306-K337 WeakPolarHBondContact O-CE 3.45Å; G306-K337 PolarHBondContact O-NZ 3.08Å; G306-H375 PolarHBondContact N-ND1 2.96Å
307S82.5Confident94.7Very high52 Ų5240 Ų4036%0.36420%0.204SC..THydrogen-bonded Turntrans-83.6-25.2178.855.10000113.3
308N85.4Confident94.7Very high57 Ų5738.4 Ų38.431%0.30520%0.199SC..THydrogen-bonded Turntrans-94.8-41.9-169.7-64.5-3.6000112.3L94 K310 F397L94-N308 HydrophobicContact CD1-CB 4.22Å; N308-K310 PolarHBondContact O-N 3.16Å; N308-F397 HydrophobicContact CB-CZ 4.21Å
309A91.1Very high94.7Very high1 Ų130.6 Ų30.61%0.00817%0.165CC..SBendtrans-90.992.2171.600000109.5W98 F305 L396 F397W98-A309 HydrophobicContact CZ2-CB 4.14Å; F305-A309 HydrophobicContact CB-CB 4.14Å; F305-A309 WeakPolarHBondContact CB-O 3.28Å; F305-A309 WeakPolarHBondContact O-CB 3.45Å; A309-L396 HydrophobicContact CB-CD1 3.44Å; A309-L396 VanDerWaalsContact CB-CD1 3.44Å; A309-F397 HydrophobicContact CB-CE1 4.19Å
310K93.3Very high94.7Very high96 Ų9632.7 Ų32.742%0.41718%0.176SC..  trans-68.7139.1177.7-63.6179.3-178.2174.90110.1W98 N308 V312 D313 E339W98-K310 PolarHBondContact NE1-O 3.29Å; N308-K310 PolarHBondContact O-N 3.16Å; K310-V312 VanDerWaalsContact C-N 3.29Å; K310-V312 HydrophobicContact CB-CG2 3.95Å; K310-V312 HydrophobicContact CD-CG2 4.41Å; K310-D313 WeakPolarHBondContact CB-OD2 3.41Å; K310-D313 PolarHBondContact O-N 3.46Å; K310-E339 WeakPolarHBondContact CA-OE1 3.47Å; K310-E339 HydrophobicContact CB-CG 4.29Å; K310-E339 WeakPolarHBondContact CB-OE1 3.38Å; K310-E339 HydrophobicContact CD-CG 4.25Å; K310-E339 HydrophobicContact CG-CG 4.21Å
311S95.5Very high94.7Very high0 Ų032.8 Ų32.80%018%0.176CC..G310 helixtrans-75.6-22.6-179.9-65.10000111.9D313 M314 K319 W336 K337 Y338 E339S311-D313 PolarHBondContact O-N 2.88Å; S311-M314 WeakPolarHBondContact O-CB 3.17Å; S311-M314 PolarHBondContact O-N 3.19Å; S311-K319 WeakPolarHBondContact O-CE 3.36Å; S311-W336 PolarHBondContact OG-NE1 3.33Å; S311-W336 VanDerWaalsContact OG-NE1 3.08Å; S311-K337 PolarHBondContact OG-O 3.3Å; S311-Y338 WeakPolarHBondContact O-CE2 3.31Å; S311-E339 PolarHBondContact N-OE2 2.73Å
312V94.4Very high94.7Very high38 Ų3832.9 Ų32.923%0.2318%0.177CC..G310 helixtrans-63.6-26.9171.9-66.10000113.7K310 M314 K319 Y338 E339 N340K310-V312 VanDerWaalsContact C-N 3.29Å; K310-V312 HydrophobicContact CB-CG2 3.95Å; K310-V312 HydrophobicContact CD-CG2 4.41Å; V312-M314 VanDerWaalsContact C-N 3.29Å; V312-K319 WeakPolarHBondContact O-CE 3.3Å; V312-K319 PolarHBondContact O-NZ 3.5Å; V312-Y338 HydrophobicContact CG1-CD1 3.95Å; V312-Y338 HydrophobicContact CG1-CE1 3.6Å; V312-E339 HydrophobicContact CG1-CB 3.68Å; V312-E339 HydrophobicContact CG2-CB 4.01Å; V312-E339 HydrophobicContact CG2-CG 4.29Å; V312-E339 PolarHBondContact N-OE2 3.48Å; V312-E339 VanDerWaalsContact N-OE2 3.1Å; V312-N340 HydrophobicContact CG1-CB 3.72Å; V312-N340 VanDerWaalsContact CG1-N 3.35Å
313D94.4Very high94.6Very high58 Ų5833.2 Ų33.231%0.3118%0.18SC..G310 helixtrans-84.2-7.6-179.1-61.2-30.8000112.6A95 K310 S311A95-D313 HydrophobicContact CB-CB 4.13Å; K310-D313 WeakPolarHBondContact CB-OD2 3.41Å; K310-D313 PolarHBondContact O-N 3.46Å; S311-D313 PolarHBondContact O-N 2.88Å
314M94.9Very high94.6Very high4 Ų437.2 Ų37.22%0.0220%0.201CC..SBendtrans-59139.7176.3-174.4-171.5-76.300110.7W98 F305 S311 V312 F318 K319 L322 W336 L421W98-M314 HydrophobicContact CD2-CB 4.29Å; W98-M314 HydrophobicContact CD2-CG 4.42Å; W98-M314 HydrophobicContact CE3-CE 4.42Å; W98-M314 HydrophobicContact CE3-CG 4.22Å; W98-M314 HydrophobicContact CH2-CE 3.35Å; W98-M314 HydrophobicContact CZ2-CB 4.47Å; W98-M314 HydrophobicContact CZ2-CE 4.01Å; W98-M314 HydrophobicContact CZ3-CE 3.61Å; W98-M314 HydrophobicContact CZ3-CG 4.3Å; F305-M314 HydrophobicContact CD2-CE 4.32Å; F305-M314 HydrophobicContact CE2-CE 3.77Å; F305-M314 HydrophobicContact CZ-CE 4.16Å; S311-M314 WeakPolarHBondContact O-CB 3.17Å; S311-M314 PolarHBondContact O-N 3.19Å; V312-M314 VanDerWaalsContact C-N 3.29Å; M314-F318 HydrophobicContact CG-CB 3.49Å; M314-F318 VanDerWaalsContact CG-CB 3.49Å; M314-F318 HydrophobicContact CG-CD2 3.78Å; M314-F318 HydrophobicContact CG-CG 4.11Å; M314-F318 HydrophobicContact SD-CB 3.41Å; M314-F318 WeakPolarHBondContact SD-CB 3.19Å; M314-F318 HydrophobicContact SD-CD2 4.47Å; M314-F318 HydrophobicContact SD-CG 4.47Å; M314-K319 HydrophobicContact CB-CG 4.12Å; M314-K319 HydrophobicContact CG-CG 4.14Å; M314-K319 WeakPolarHBondContact O-CE 3.32Å; M314-K319 PolarHBondContact O-NZ 3.22Å; M314-K319 HydrophobicContact SD-CG 3.84Å; M314-L322 HydrophobicContact CE-CD1 3.97Å; M314-L322 HydrophobicContact SD-CD1 3.95Å; M314-W336 HydrophobicContact CE-CZ2 4.06Å; M314-W336 HydrophobicContact SD-CZ2 4.26Å; M314-L421 HydrophobicContact CE-CD1 4.42Å
315P95.1Very high94.7Very high25 Ų2537 Ų3716%0.16220%0.2CC..  trans-54142.5171.3-27.334.2000112.1W98 K99 E317 F318 K319W98-P315 HydrophobicContact CB-CG 4.48Å; K99-P315 HydrophobicContact CG-CG 3.83Å; P315-E317 PolarHBondContact O-N 3.22Å; P315-E317 VanDerWaalsContact O-N 3.16Å; P315-F318 HydrophobicContact CB-CG 4.44Å; P315-F318 HydrophobicContact CG-CD2 4.13Å; P315-F318 HydrophobicContact CG-CE2 4.08Å; P315-F318 HydrophobicContact CG-CZ 4.45Å; P315-F318 PolarHBondContact O-N 3.28Å; P315-K319 PolarHBondContact O-N 2.75Å; P315-K319 VanDerWaalsContact O-N 3.15Å
316D94.7Very high94.8Very high99 Ų9936.9 Ų36.953%0.52920%0.199SC..Hα-helixtrans-59.3-29.9179.3-67.8-15.7000112F318 K319 N320D316-F318 VanDerWaalsContact C-N 3.35Å; D316-F318 PolarHBondContact O-N 2.91Å; D316-K319 PolarHBondContact O-N 3.46Å; D316-K319 IonicContact OD1-NZ 3.17Å; D316-N320 VanDerWaalsContact O-CB 3.24Å; D316-N320 WeakPolarHBondContact O-CB 3.46Å; D316-N320 PolarHBondContact O-N 3.27Å; D316-N320 PolarHBondContact O-ND2 3.32Å
317E96.4Very high95.1Very high127 Ų12743.4 Ų43.459%0.59322%0.224SC*.Hα-helixtrans-55.3-47172.3-175.4178.6-169.400112.3P315 S321 A422P315-E317 PolarHBondContact O-N 3.22Å; P315-E317 VanDerWaalsContact O-N 3.16Å; E317-S321 WeakPolarHBondContact O-CB 3.12Å; E317-S321 PolarHBondContact O-N 2.94Å; E317-A422 HydrophobicContact CG-CB 3.64Å; E317-A422 VanDerWaalsContact OE1-CB 3.3Å; E317-A422 WeakPolarHBondContact OE1-CB 3.22Å
318F97.3Very high95.9Very high9 Ų943.1 Ų43.14%0.03922%0.222CC..Hα-helixtrans-71.8-39179.3-60.9-4.6000110.9W98 M314 P315 D316 S321 L322 L421 A422W98-F318 HydrophobicContact CE3-CD2 4.22Å; W98-F318 HydrophobicContact CE3-CE2 4.35Å; M314-F318 HydrophobicContact CG-CB 3.49Å; M314-F318 VanDerWaalsContact CG-CB 3.49Å; M314-F318 HydrophobicContact CG-CD2 3.78Å; M314-F318 HydrophobicContact CG-CG 4.11Å; M314-F318 HydrophobicContact SD-CB 3.41Å; M314-F318 WeakPolarHBondContact SD-CB 3.19Å; M314-F318 HydrophobicContact SD-CD2 4.47Å; M314-F318 HydrophobicContact SD-CG 4.47Å; P315-F318 HydrophobicContact CB-CG 4.44Å; P315-F318 HydrophobicContact CG-CD2 4.13Å; P315-F318 HydrophobicContact CG-CE2 4.08Å; P315-F318 HydrophobicContact CG-CZ 4.45Å; P315-F318 PolarHBondContact O-N 3.28Å; D316-F318 VanDerWaalsContact C-N 3.35Å; D316-F318 PolarHBondContact O-N 2.91Å; F318-S321 PolarHBondContact O-N 3.41Å; F318-L322 WeakPolarHBondContact O-CB 3.43Å; F318-L322 WeakPolarHBondContact O-CG 3.42Å; F318-L322 PolarHBondContact O-N 3.14Å; F318-L421 HydrophobicContact CB-CB 3.97Å; F318-L421 HydrophobicContact CD1-CB 3.91Å; F318-L421 HydrophobicContact CD2-CB 3.92Å; F318-L421 HydrophobicContact CD2-CD1 3.83Å; F318-L421 HydrophobicContact CE1-CB 4.4Å; F318-L421 HydrophobicContact CE2-CB 4.42Å; F318-L421 HydrophobicContact CE2-CD1 4.31Å; F318-L421 HydrophobicContact CG-CB 3.66Å; F318-L421 HydrophobicContact CG-CD1 4.34Å; F318-A422 HydrophobicContact CD1-CB 3.85Å; F318-A422 HydrophobicContact CE1-CB 3.9Å
319K97.2Very high96.5Very high15 Ų1541 Ų417%0.06521%0.21CC..Hα-helixtrans-63.2-43.3176.5-64.7177.1-176159.60111.8S311 V312 M314 P315 D316 L322 A323 W336 Y338 I345S311-K319 WeakPolarHBondContact O-CE 3.36Å; V312-K319 WeakPolarHBondContact O-CE 3.3Å; V312-K319 PolarHBondContact O-NZ 3.5Å; M314-K319 HydrophobicContact CB-CG 4.12Å; M314-K319 HydrophobicContact CG-CG 4.14Å; M314-K319 WeakPolarHBondContact O-CE 3.32Å; M314-K319 PolarHBondContact O-NZ 3.22Å; M314-K319 HydrophobicContact SD-CG 3.84Å; P315-K319 PolarHBondContact O-N 2.75Å; P315-K319 VanDerWaalsContact O-N 3.15Å; D316-K319 PolarHBondContact O-N 3.46Å; D316-K319 IonicContact OD1-NZ 3.17Å; K319-L322 PolarHBondContact O-N 3.29Å; K319-A323 WeakPolarHBondContact O-CB 3.45Å; K319-A323 PolarHBondContact O-N 3.07Å; K319-W336 HydrophobicContact CG-CH2 4.36Å; K319-Y338 WeakPolarHBondContact CD-OH 3.48Å; K319-Y338 WeakPolarHBondContact CE-OH 3.47Å; K319-Y338 PolarHBondContact NZ-OH 3.18Å; K319-I345 HydrophobicContact CB-CD1 3.91Å; K319-I345 HydrophobicContact CB-CG2 4.29Å; K319-I345 HydrophobicContact CD-CD1 3.85Å
320N97.8Very high96.7Very high78 Ų7844.9 Ų44.942%0.41724%0.235SC..Hα-helixtrans-66.7-43.6178.1-72.8-37.8000111.2D316 L322 A323 D324D316-N320 VanDerWaalsContact O-CB 3.24Å; D316-N320 WeakPolarHBondContact O-CB 3.46Å; D316-N320 PolarHBondContact O-N 3.27Å; D316-N320 PolarHBondContact O-ND2 3.32Å; N320-L322 PolarHBondContact O-N 2.97Å; N320-A323 WeakPolarHBondContact O-CB 3.35Å; N320-A323 PolarHBondContact O-N 3.42Å; N320-D324 PolarHBondContact O-N 3.43Å
321S98.2Very high96.9Very high4 Ų446 Ų463%0.02825%0.245CC..Hα-helixtrans-57.7-47173.2166.50000111.8E317 F318 A323 D324 V325 L421 T424E317-S321 WeakPolarHBondContact O-CB 3.12Å; E317-S321 PolarHBondContact O-N 2.94Å; F318-S321 PolarHBondContact O-N 3.41Å; S321-A323 PolarHBondContact O-N 3.48Å; S321-D324 PolarHBondContact O-N 3.08Å; S321-V325 WeakPolarHBondContact O-CG2 3.47Å; S321-V325 PolarHBondContact O-N 3.37Å; S321-L421 WeakPolarHBondContact CB-O 3.28Å; S321-L421 PolarHBondContact OG-O 3.18Å; S321-T424 WeakPolarHBondContact CA-OG1 3.47Å; S321-T424 WeakPolarHBondContact OG-CA 3.48Å; S321-T424 PolarHBondContact OG-N 2.88Å; S321-T424 PolarHBondContact OG-OG1 3.15Å
322L98.2Very high97.1Very high3 Ų346.1 Ų46.12%0.01625%0.246CC..Hα-helixtrans-61.1-42.8174.8-73.8176.2000112.1M314 F318 K319 N320 D324 V325 F326 W336 L421 M427M314-L322 HydrophobicContact CE-CD1 3.97Å; M314-L322 HydrophobicContact SD-CD1 3.95Å; F318-L322 WeakPolarHBondContact O-CB 3.43Å; F318-L322 WeakPolarHBondContact O-CG 3.42Å; F318-L322 PolarHBondContact O-N 3.14Å; K319-L322 PolarHBondContact O-N 3.29Å; N320-L322 PolarHBondContact O-N 2.97Å; L322-D324 VanDerWaalsContact C-N 3.33Å; L322-D324 PolarHBondContact O-N 3.11Å; L322-V325 WeakPolarHBondContact O-CB 3.26Å; L322-V325 PolarHBondContact O-N 3.26Å; L322-F326 HydrophobicContact CB-CE1 4.31Å; L322-F326 HydrophobicContact CB-CE2 3.99Å; L322-F326 HydrophobicContact CB-CZ 3.75Å; L322-F326 HydrophobicContact CD2-CE1 4.39Å; L322-F326 HydrophobicContact CD2-CZ 4.33Å; L322-F326 HydrophobicContact CG-CZ 4.46Å; L322-F326 WeakPolarHBondContact O-CD1 3.42Å; L322-F326 WeakPolarHBondContact O-CD2 3.34Å; L322-F326 WeakPolarHBondContact O-CG 3.39Å; L322-F326 PolarHBondContact O-N 2.84Å; L322-W336 HydrophobicContact CD1-CH2 3.91Å; L322-W336 HydrophobicContact CD1-CZ2 3.84Å; L322-L421 HydrophobicContact CD2-CD2 4.27Å; L322-M427 HydrophobicContact CD2-CE 4.41Å
323A98.2Very high97.3Very high9 Ų944.3 Ų44.37%0.07424%0.236CC..Hα-helixtrans-59.9-41.7175.900000112.4K319 N320 S321 F326 K327 I345 V346 L349K319-A323 WeakPolarHBondContact O-CB 3.45Å; K319-A323 PolarHBondContact O-N 3.07Å; N320-A323 WeakPolarHBondContact O-CB 3.35Å; N320-A323 PolarHBondContact O-N 3.42Å; S321-A323 PolarHBondContact O-N 3.48Å; A323-F326 PolarHBondContact O-N 3.49Å; A323-K327 WeakPolarHBondContact O-CB 3.27Å; A323-K327 PolarHBondContact O-N 2.82Å; A323-I345 HydrophobicContact CB-CG2 3.79Å; A323-V346 HydrophobicContact CB-CG1 3.88Å; A323-L349 HydrophobicContact CB-CD1 4.45Å
324D98.4Very high97.5Very high85 Ų8541.6 Ų41.646%0.45522%0.221SC..Hα-helixtrans-66.2-40.5175.6-74.6-25.9000111.9N320 S321 L322 F326 K327 S328 T424N320-D324 PolarHBondContact O-N 3.43Å; S321-D324 PolarHBondContact O-N 3.08Å; L322-D324 VanDerWaalsContact C-N 3.33Å; L322-D324 PolarHBondContact O-N 3.11Å; D324-F326 VanDerWaalsContact C-N 3.35Å; D324-F326 PolarHBondContact O-N 2.88Å; D324-K327 PolarHBondContact O-N 3.28Å; D324-S328 WeakPolarHBondContact O-CB 3.17Å; D324-S328 PolarHBondContact O-N 2.94Å; D324-T424 HydrophobicContact CB-CG2 3.51Å
325V98.6Very high97.6Very high0 Ų041.4 Ų41.40%022%0.22CC..Hα-helixtrans-57.5-49.7171.91710000110S321 L322 K327 S328 M329 T424 M427 K428 L431S321-V325 WeakPolarHBondContact O-CG2 3.47Å; S321-V325 PolarHBondContact O-N 3.37Å; L322-V325 WeakPolarHBondContact O-CB 3.26Å; L322-V325 PolarHBondContact O-N 3.26Å; V325-K327 PolarHBondContact O-N 2.87Å; V325-S328 PolarHBondContact O-N 3.22Å; V325-S328 VanDerWaalsContact O-N 3.09Å; V325-S328 PolarHBondContact O-OG 3.49Å; V325-M329 HydrophobicContact CG1-SD 3.85Å; V325-M329 WeakPolarHBondContact O-CG 3.33Å; V325-M329 PolarHBondContact O-N 3.38Å; V325-T424 HydrophobicContact CG2-CG2 3.97Å; V325-T424 WeakPolarHBondContact CG2-O 3.38Å; V325-M427 HydrophobicContact CG2-CB 3.77Å; V325-K428 HydrophobicContact CG2-CB 4.34Å; V325-L431 HydrophobicContact CG1-CD1 3.83Å
326F98.5Very high97.8Very high0 Ų040.3 Ų40.30%021%0.212CC..Hα-helixtrans-59.3-46.7-179.1-55.8-23.7000111.6I303 L322 A323 D324 S328 M329 F334 W336 V346 L349 N351 V352I303-F326 HydrophobicContact CD1-CE1 3.64Å; I303-F326 HydrophobicContact CD1-CZ 3.59Å; L322-F326 HydrophobicContact CB-CE1 4.31Å; L322-F326 HydrophobicContact CB-CE2 3.99Å; L322-F326 HydrophobicContact CB-CZ 3.75Å; L322-F326 HydrophobicContact CD2-CE1 4.39Å; L322-F326 HydrophobicContact CD2-CZ 4.33Å; L322-F326 HydrophobicContact CG-CZ 4.46Å; L322-F326 WeakPolarHBondContact O-CD1 3.42Å; L322-F326 WeakPolarHBondContact O-CD2 3.34Å; L322-F326 WeakPolarHBondContact O-CG 3.39Å; L322-F326 PolarHBondContact O-N 2.84Å; A323-F326 PolarHBondContact O-N 3.49Å; D324-F326 VanDerWaalsContact C-N 3.35Å; D324-F326 PolarHBondContact O-N 2.88Å; F326-S328 VanDerWaalsContact C-N 3.25Å; F326-S328 PolarHBondContact O-N 3.29Å; F326-M329 PolarHBondContact O-N 2.81Å; F326-F334 HydrophobicContact CB-CD2 3.98Å; F326-F334 HydrophobicContact CB-CE2 4.08Å; F326-F334 HydrophobicContact CD1-CB 4.11Å; F326-F334 AromaticContact CD1-CD1 3.38Å; F326-F334 HydrophobicContact CD1-CD1 3.38Å; F326-F334 AromaticContact CD1-CD2 3.53Å; F326-F334 HydrophobicContact CD1-CD2 3.53Å; F326-F334 AromaticContact CD1-CE1 3.53Å; F326-F334 HydrophobicContact CD1-CE1 3.53Å; F326-F334 AromaticContact CD1-CE2 3.69Å; F326-F334 HydrophobicContact CD1-CE2 3.69Å; F326-F334 AromaticContact CD1-CG 3.37Å; F326-F334 HydrophobicContact CD1-CG 3.37Å; F326-F334 AromaticContact CD1-CZ 3.68Å; F326-F334 HydrophobicContact CD1-CZ 3.68Å; F326-F334 HydrophobicContact CE1-CB 4.14Å; F326-F334 AromaticContact CE1-CD1 3.36Å; F326-F334 HydrophobicContact CE1-CD1 3.36Å; F326-F334 HydrophobicContact CE1-CD2 4.3Å; F326-F334 AromaticContact CE1-CE1 3.75Å; F326-F334 HydrophobicContact CE1-CE1 3.75Å; F326-F334 AromaticContact CE1-CG 3.67Å; F326-F334 HydrophobicContact CE1-CG 3.67Å; F326-F334 HydrophobicContact CE1-CZ 4.36Å; F326-F334 HydrophobicContact CG-CD1 4.45Å; F326-F334 AromaticContact CG-CD2 3.92Å; F326-F334 HydrophobicContact CG-CD2 3.92Å; F326-F334 HydrophobicContact CG-CE2 4.24Å; F326-F334 HydrophobicContact CG-CG 4.03Å; F326-F334 HydrophobicContact CZ-CD1 4.41Å; F326-W336 AromaticContact CE2-CE3 3.82Å; F326-W336 HydrophobicContact CE2-CE3 3.82Å; F326-W336 AromaticContact CE2-CZ3 3.96Å; F326-W336 HydrophobicContact CE2-CZ3 3.96Å; F326-W336 HydrophobicContact CZ-CE3 4.14Å; F326-W336 HydrophobicContact CZ-CZ3 4.44Å; F326-V346 HydrophobicContact CD2-CG1 4.21Å; F326-V346 HydrophobicContact CE2-CG1 4.24Å; F326-L349 HydrophobicContact CB-CD1 4.01Å; F326-L349 HydrophobicContact CD2-CD1 4.38Å; F326-N351 PolarHBondContact O-ND2 3.48Å; F326-V352 HydrophobicContact CB-CG2 3.75Å; F326-V352 HydrophobicContact CD2-CG1 4.37Å; F326-V352 HydrophobicContact CD2-CG2 3.44Å; F326-V352 VanDerWaalsContact CD2-CG2 3.44Å; F326-V352 HydrophobicContact CE2-CG1 4.4Å; F326-V352 HydrophobicContact CE2-CG2 4.24Å; F326-V352 HydrophobicContact CG-CG2 3.76Å
327K97.9Very high97.9Very high152 Ų15236.4 Ų36.466%0.66119%0.191SC*.Hα-helixtrans-60.9-34.7176.4-173.8178.7-178.5178.90112.5A323 D324 V325 M329 L349A323-K327 WeakPolarHBondContact O-CB 3.27Å; A323-K327 PolarHBondContact O-N 2.82Å; D324-K327 PolarHBondContact O-N 3.28Å; V325-K327 PolarHBondContact O-N 2.87Å; K327-M329 VanDerWaalsContact C-N 3.28Å; K327-M329 PolarHBondContact O-N 3.47Å; K327-L349 HydrophobicContact CB-CD2 4.4Å
328S98.1Very high97.9Very high46 Ų4630.5 Ų30.532%0.32216%0.163SC..THydrogen-bonded Turntrans-80.4-4.5-179.385.40000114.5D324 V325 F326 P330 K428D324-S328 WeakPolarHBondContact O-CB 3.17Å; D324-S328 PolarHBondContact O-N 2.94Å; V325-S328 PolarHBondContact O-N 3.22Å; V325-S328 VanDerWaalsContact O-N 3.09Å; V325-S328 PolarHBondContact O-OG 3.49Å; F326-S328 VanDerWaalsContact C-N 3.25Å; F326-S328 PolarHBondContact O-N 3.29Å; S328-P330 VanDerWaalsContact C-CD 3.46Å; S328-K428 PolarHBondContact O-NZ 2.86Å; S328-K428 WeakPolarHBondContact OG-CD 3.43Å; S328-K428 PolarHBondContact OG-NZ 2.79Å
329M98Very high97.7Very high12 Ų1232.1 Ų32.16%0.05917%0.171CC..  trans-126.561.8-177.3-63.4-178.373.100111.8V325 F326 K327 D331 T332 F334 N351 K428 L431 E432 I435V325-M329 HydrophobicContact CG1-SD 3.85Å; V325-M329 WeakPolarHBondContact O-CG 3.33Å; V325-M329 PolarHBondContact O-N 3.38Å; F326-M329 PolarHBondContact O-N 2.81Å; K327-M329 VanDerWaalsContact C-N 3.28Å; K327-M329 PolarHBondContact O-N 3.47Å; M329-D331 PolarHBondContact O-N 3Å; M329-D331 VanDerWaalsContact O-N 3.14Å; M329-T332 HydrophobicContact CE-CG2 4.46Å; M329-T332 WeakPolarHBondContact O-CB 3.21Å; M329-T332 PolarHBondContact O-N 3.31Å; M329-F334 HydrophobicContact CB-CE2 4.06Å; M329-F334 HydrophobicContact CB-CZ 4Å; M329-F334 HydrophobicContact CE-CZ 4.48Å; M329-F334 HydrophobicContact SD-CZ 3.89Å; M329-N351 PolarHBondContact O-ND2 2.92Å; M329-K428 HydrophobicContact CG-CG 4.38Å; M329-K428 HydrophobicContact SD-CG 4.21Å; M329-L431 HydrophobicContact CE-CB 4.4Å; M329-L431 HydrophobicContact SD-CD1 4.46Å; M329-E432 HydrophobicContact CE-CG 4.04Å; M329-I435 HydrophobicContact CE-CD1 4.06Å
330P96.6Very high97.6Very high83 Ų8334.7 Ų34.754%0.53919%0.186SC..THydrogen-bonded Turntrans-63.6-22.7-173.226.7-36.3000114.4R297 S328 T332R297-P330 WeakPolarHBondContact CD-O 3.03Å; R297-P330 PolarHBondContact NE-O 3.27Å; S328-P330 VanDerWaalsContact C-CD 3.46Å; P330-T332 VanDerWaalsContact C-N 3.25Å; P330-T332 PolarHBondContact O-N 3.48Å
331D97.2Very high97.2Very high118 Ų11834.7 Ų34.763%0.63119%0.188SC*.THydrogen-bonded Turntrans-84.97.6175.6-62.3-38.3000113.5R297 N299 M329R297-D331 WeakPolarHBondContact CB-O 3.1Å; N299-D331 PolarHBondContact N-O 2.6Å; M329-D331 PolarHBondContact O-N 3Å; M329-D331 VanDerWaalsContact O-N 3.14Å
332T98.6Very high96.8Very high4 Ų438.4 Ų38.43%0.02521%0.214CC..EExtended strand (participates in β ladder)trans-121.5128.8-179.6-50.40000110.5N299 V301 M329 P330 F334 N351N299-T332 HydrophobicContact CB-CG2 3.86Å; N299-T332 WeakPolarHBondContact O-CA 3.42Å; V301-T332 HydrophobicContact CB-CG2 4.42Å; V301-T332 HydrophobicContact CG2-CG2 3.65Å; M329-T332 HydrophobicContact CE-CG2 4.46Å; M329-T332 WeakPolarHBondContact O-CB 3.21Å; M329-T332 PolarHBondContact O-N 3.31Å; P330-T332 VanDerWaalsContact C-N 3.25Å; P330-T332 PolarHBondContact O-N 3.48Å; T332-F334 HydrophobicContact CG2-CD2 4.47Å; T332-F334 HydrophobicContact CG2-CE1 4.13Å; T332-F334 HydrophobicContact CG2-CE2 3.91Å; T332-F334 HydrophobicContact CG2-CZ 3.73Å; T332-N351 WeakPolarHBondContact O-CB 3.33Å; T332-N351 PolarHBondContact O-ND2 3.26Å; T332-N351 VanDerWaalsContact O-ND2 3.12Å
333T98.7Very high96.5Very high0 Ų039 Ų390%022%0.217CC..EExtended strand (participates in β ladder)trans-87.1132.3170.4-62.20000109.5I293 R297 N299 N300 V301 I335I293-T333 HydrophobicContact CG2-CG2 3.58Å; R297-T333 WeakPolarHBondContact CB-OG1 3.35Å; R297-T333 WeakPolarHBondContact CD-OG1 2.94Å; R297-T333 WeakPolarHBondContact CG-OG1 3.49Å; N299-T333 PolarHBondContact O-N 3.43Å; N300-T333 CarbonylContact C-O 3.59Å; N300-T333 WeakPolarHBondContact CA-O 3.43Å; N300-T333 VanDerWaalsContact OD1-CB 3.31Å; N300-T333 WeakPolarHBondContact OD1-CB 3.34Å; V301-T333 PolarHBondContact N-O 2.97Å; T333-I335 HydrophobicContact CG2-CG1 4.38Å
334F98.6Very high96.2Very high0 Ų043 Ų430%024%0.242CC..EExtended strand (participates in β ladder)trans-111.5116.6175.3-62.9-87.1000109.7V301 I303 F326 M329 T332 N351 V352 H353 L431V301-F334 HydrophobicContact CB-CD1 3.68Å; V301-F334 HydrophobicContact CB-CE1 3.9Å; V301-F334 HydrophobicContact CG1-CD1 3.97Å; V301-F334 HydrophobicContact CG1-CE1 4.18Å; V301-F334 HydrophobicContact CG2-CD1 4.26Å; V301-F334 HydrophobicContact CG2-CE1 3.97Å; V301-F334 CarbonylContact O-C 3.55Å; V301-F334 WeakPolarHBondContact O-CA 2.97Å; I303-F334 HydrophobicContact CD1-CD1 4.17Å; F326-F334 HydrophobicContact CB-CD2 3.98Å; F326-F334 HydrophobicContact CB-CE2 4.08Å; F326-F334 HydrophobicContact CD1-CB 4.11Å; F326-F334 AromaticContact CD1-CD1 3.38Å; F326-F334 HydrophobicContact CD1-CD1 3.38Å; F326-F334 AromaticContact CD1-CD2 3.53Å; F326-F334 HydrophobicContact CD1-CD2 3.53Å; F326-F334 AromaticContact CD1-CE1 3.53Å; F326-F334 HydrophobicContact CD1-CE1 3.53Å; F326-F334 AromaticContact CD1-CE2 3.69Å; F326-F334 HydrophobicContact CD1-CE2 3.69Å; F326-F334 AromaticContact CD1-CG 3.37Å; F326-F334 HydrophobicContact CD1-CG 3.37Å; F326-F334 AromaticContact CD1-CZ 3.68Å; F326-F334 HydrophobicContact CD1-CZ 3.68Å; F326-F334 HydrophobicContact CE1-CB 4.14Å; F326-F334 AromaticContact CE1-CD1 3.36Å; F326-F334 HydrophobicContact CE1-CD1 3.36Å; F326-F334 HydrophobicContact CE1-CD2 4.3Å; F326-F334 AromaticContact CE1-CE1 3.75Å; F326-F334 HydrophobicContact CE1-CE1 3.75Å; F326-F334 AromaticContact CE1-CG 3.67Å; F326-F334 HydrophobicContact CE1-CG 3.67Å; F326-F334 HydrophobicContact CE1-CZ 4.36Å; F326-F334 HydrophobicContact CG-CD1 4.45Å; F326-F334 AromaticContact CG-CD2 3.92Å; F326-F334 HydrophobicContact CG-CD2 3.92Å; F326-F334 HydrophobicContact CG-CE2 4.24Å; F326-F334 HydrophobicContact CG-CG 4.03Å; F326-F334 HydrophobicContact CZ-CD1 4.41Å; M329-F334 HydrophobicContact CB-CE2 4.06Å; M329-F334 HydrophobicContact CB-CZ 4Å; M329-F334 HydrophobicContact CE-CZ 4.48Å; M329-F334 HydrophobicContact SD-CZ 3.89Å; T332-F334 HydrophobicContact CG2-CD2 4.47Å; T332-F334 HydrophobicContact CG2-CE1 4.13Å; T332-F334 HydrophobicContact CG2-CE2 3.91Å; T332-F334 HydrophobicContact CG2-CZ 3.73Å; F334-N351 PolarHBondContact N-O 2.68Å; F334-V352 HydrophobicContact CB-CG2 4.4Å; F334-V352 CarbonylContact O-C 3.58Å; F334-V352 WeakPolarHBondContact O-CA 3.29Å; F334-H353 PolarHBondContact O-N 2.82Å; F334-L431 HydrophobicContact CE1-CD1 4.21Å
335I98.4Very high95.9Very high1 Ų140.6 Ų40.61%0.00523%0.23CC..EExtended strand (participates in β ladder)trans-100.7114.8170.7-61.1173.2000106.6W290 I293 L294 V301 F302 I303 T333 H353 L358 L363W290-I335 HydrophobicContact CE3-CD1 3.99Å; W290-I335 HydrophobicContact CE3-CG1 4.33Å; W290-I335 HydrophobicContact CE3-CG2 4.13Å; W290-I335 HydrophobicContact CH2-CG2 4.39Å; W290-I335 HydrophobicContact CZ3-CD1 4.46Å; W290-I335 HydrophobicContact CZ3-CG1 4.31Å; W290-I335 HydrophobicContact CZ3-CG2 3.76Å; I293-I335 HydrophobicContact CG2-CD1 4.04Å; I293-I335 HydrophobicContact CG2-CG1 4.08Å; L294-I335 HydrophobicContact CD2-CD1 3.76Å; L294-I335 HydrophobicContact CG-CD1 4.41Å; V301-I335 PolarHBondContact O-N 3.43Å; F302-I335 CarbonylContact C-O 3.55Å; F302-I335 WeakPolarHBondContact CA-O 3.41Å; F302-I335 HydrophobicContact CD2-CB 4.25Å; F302-I335 HydrophobicContact CD2-CG2 4Å; F302-I335 WeakPolarHBondContact CD2-O 3.35Å; F302-I335 HydrophobicContact CE2-CG2 4.45Å; I303-I335 PolarHBondContact N-O 3.3Å; T333-I335 HydrophobicContact CG2-CG1 4.38Å; I335-H353 WeakPolarHBondContact CA-O 3.38Å; I335-L358 HydrophobicContact CG2-CD1 3.73Å; I335-L358 HydrophobicContact CG2-CD2 4.25Å; I335-L363 HydrophobicContact CD1-CD2 3.81Å; I335-L363 HydrophobicContact CG2-CD1 4.24Å
336W98Very high95.7Very high1 Ų140.7 Ų40.70%0.00423%0.23CC..EExtended strand (participates in β ladder)trans-121.1119.8-173.9-172.310.1000111.2I303 S311 M314 K319 L322 F326 Y338 V346 H353 L354 G355I303-W336 HydrophobicContact CB-CB 4.24Å; I303-W336 HydrophobicContact CB-CG 4.03Å; I303-W336 VanDerWaalsContact CG2-CD1 3.49Å; I303-W336 HydrophobicContact CG2-CG 4.17Å; S311-W336 PolarHBondContact OG-NE1 3.33Å; S311-W336 VanDerWaalsContact OG-NE1 3.08Å; M314-W336 HydrophobicContact CE-CZ2 4.06Å; M314-W336 HydrophobicContact SD-CZ2 4.26Å; K319-W336 HydrophobicContact CG-CH2 4.36Å; L322-W336 HydrophobicContact CD1-CH2 3.91Å; L322-W336 HydrophobicContact CD1-CZ2 3.84Å; F326-W336 AromaticContact CE2-CE3 3.82Å; F326-W336 HydrophobicContact CE2-CE3 3.82Å; F326-W336 AromaticContact CE2-CZ3 3.96Å; F326-W336 HydrophobicContact CE2-CZ3 3.96Å; F326-W336 HydrophobicContact CZ-CE3 4.14Å; F326-W336 HydrophobicContact CZ-CZ3 4.44Å; W336-Y338 AromaticContact CD2-CD2 3.8Å; W336-Y338 HydrophobicContact CD2-CD2 3.8Å; W336-Y338 AromaticContact CE2-CD2 3.52Å; W336-Y338 HydrophobicContact CE3-CD2 4Å; W336-Y338 HydrophobicContact CE3-CE2 4.48Å; W336-Y338 HydrophobicContact CG-CD2 4.49Å; W336-Y338 AromaticContact CH2-CD2 3.77Å; W336-Y338 HydrophobicContact CH2-CD2 3.77Å; W336-Y338 AromaticContact CH2-CE2 3.54Å; W336-Y338 HydrophobicContact CH2-CE2 3.54Å; W336-Y338 AromaticContact CZ2-CD2 3.53Å; W336-Y338 HydrophobicContact CZ2-CD2 3.53Å; W336-Y338 AromaticContact CZ2-CE2 3.6Å; W336-Y338 HydrophobicContact CZ2-CE2 3.6Å; W336-Y338 AromaticContact CZ3-CD2 3.99Å; W336-Y338 HydrophobicContact CZ3-CD2 3.99Å; W336-Y338 AromaticContact CZ3-CE2 4Å; W336-Y338 HydrophobicContact CZ3-CE2 4Å; W336-Y338 AromaticContact NE1-CD2 4Å; W336-Y338 PolarHBondContact O-N 2.93Å; W336-Y338 VanDerWaalsContact O-N 3.11Å; W336-V346 HydrophobicContact CZ3-CG1 4.09Å; W336-V346 HydrophobicContact CZ3-CG2 4.48Å; W336-H353 PolarHBondContact N-O 3.01Å; W336-L354 HydrophobicContact CB-CD2 3.93Å; W336-L354 HydrophobicContact CD2-CD2 4.42Å; W336-L354 HydrophobicContact CE3-CD2 4.01Å; W336-L354 HydrophobicContact CG-CD2 4.43Å; W336-L354 WeakPolarHBondContact O-CA 3.29Å; W336-G355 PolarHBondContact O-N 3.29Å
337K97.2Very high95.2Very high18 Ų1845 Ų458%0.07825%0.253CS..EExtended strand (participates in β ladder)trans-64.1108.2169.3-169.1-97.4176.9177.60108.7I303 G306 S311 E339 G355 D356 L358I303-K337 PolarHBondContact O-N 3Å; G306-K337 WeakPolarHBondContact O-CE 3.45Å; G306-K337 PolarHBondContact O-NZ 3.08Å; S311-K337 PolarHBondContact OG-O 3.3Å; K337-E339 WeakPolarHBondContact CE-OE1 3.42Å; K337-E339 IonicContact NZ-OE1 2.57Å; K337-E339 PolarHBondContact NZ-OE1 3.09Å; K337-G355 CarbonylContact C-O 3.57Å; K337-G355 VanDerWaalsContact CA-O 3.27Å; K337-G355 WeakPolarHBondContact CA-O 3.5Å; K337-D356 WeakPolarHBondContact CE-O 3.49Å; K337-L358 HydrophobicContact CB-CD1 3.86Å; K337-L358 HydrophobicContact CG-CD1 4.5Å
338Y95.9Very high95Very high2 Ų243.9 Ų43.91%0.00825%0.25CC..  trans-150.7125.6-170.2-159-89.3000110.4S311 V312 K319 W336 N340 D343 L354 G355 D356S311-Y338 WeakPolarHBondContact O-CE2 3.31Å; V312-Y338 HydrophobicContact CG1-CD1 3.95Å; V312-Y338 HydrophobicContact CG1-CE1 3.6Å; K319-Y338 WeakPolarHBondContact CD-OH 3.48Å; K319-Y338 WeakPolarHBondContact CE-OH 3.47Å; K319-Y338 PolarHBondContact NZ-OH 3.18Å; W336-Y338 AromaticContact CD2-CD2 3.8Å; W336-Y338 HydrophobicContact CD2-CD2 3.8Å; W336-Y338 AromaticContact CE2-CD2 3.52Å; W336-Y338 HydrophobicContact CE3-CD2 4Å; W336-Y338 HydrophobicContact CE3-CE2 4.48Å; W336-Y338 HydrophobicContact CG-CD2 4.49Å; W336-Y338 AromaticContact CH2-CD2 3.77Å; W336-Y338 HydrophobicContact CH2-CD2 3.77Å; W336-Y338 AromaticContact CH2-CE2 3.54Å; W336-Y338 HydrophobicContact CH2-CE2 3.54Å; W336-Y338 AromaticContact CZ2-CD2 3.53Å; W336-Y338 HydrophobicContact CZ2-CD2 3.53Å; W336-Y338 AromaticContact CZ2-CE2 3.6Å; W336-Y338 HydrophobicContact CZ2-CE2 3.6Å; W336-Y338 AromaticContact CZ3-CD2 3.99Å; W336-Y338 HydrophobicContact CZ3-CD2 3.99Å; W336-Y338 AromaticContact CZ3-CE2 4Å; W336-Y338 HydrophobicContact CZ3-CE2 4Å; W336-Y338 AromaticContact NE1-CD2 4Å; W336-Y338 PolarHBondContact O-N 2.93Å; W336-Y338 VanDerWaalsContact O-N 3.11Å; Y338-N340 HydrophobicContact CD1-CB 4.25Å; Y338-N340 WeakPolarHBondContact CD1-O 3.29Å; Y338-N340 HydrophobicContact CE1-CB 3.94Å; Y338-N340 WeakPolarHBondContact CE1-O 3.45Å; Y338-N340 PolarHBondContact O-N 3.26Å; Y338-D343 HydrophobicContact CE1-CB 3.72Å; Y338-D343 WeakPolarHBondContact CE1-OD2 3.44Å; Y338-D343 PolarHBondContact OH-OD2 3.42Å; Y338-L354 HydrophobicContact CD1-CD1 4.06Å; Y338-L354 HydrophobicContact CG-CD1 4.42Å; Y338-L354 HydrophobicContact CG-CD2 4.31Å; Y338-G355 PolarHBondContact N-O 3.26Å; Y338-G355 CarbonylContact O-C 3.6Å; Y338-D356 PolarHBondContact O-N 3.14Å
339E93.9Very high94.9Very high43 Ų4342.7 Ų42.720%0.20124%0.24CC..SBendtrans-74.5-25.3-168.7-60.370.9-163.600112.8K310 S311 V312 K337K310-E339 WeakPolarHBondContact CA-OE1 3.47Å; K310-E339 HydrophobicContact CB-CG 4.29Å; K310-E339 WeakPolarHBondContact CB-OE1 3.38Å; K310-E339 HydrophobicContact CD-CG 4.25Å; K310-E339 HydrophobicContact CG-CG 4.21Å; S311-E339 PolarHBondContact N-OE2 2.73Å; V312-E339 HydrophobicContact CG1-CB 3.68Å; V312-E339 HydrophobicContact CG2-CB 4.01Å; V312-E339 HydrophobicContact CG2-CG 4.29Å; V312-E339 PolarHBondContact N-OE2 3.48Å; V312-E339 VanDerWaalsContact N-OE2 3.1Å; K337-E339 WeakPolarHBondContact CE-OE1 3.42Å; K337-E339 IonicContact NZ-OE1 2.57Å; K337-E339 PolarHBondContact NZ-OE1 3.09Å
340N93.8Very high94.8Very high70 Ų7048 Ų4837%0.37427%0.269SS..  trans-106.791.2174.6176.514.5000111.4V312 Y338 S342 D343V312-N340 HydrophobicContact CG1-CB 3.72Å; V312-N340 VanDerWaalsContact CG1-N 3.35Å; Y338-N340 HydrophobicContact CD1-CB 4.25Å; Y338-N340 WeakPolarHBondContact CD1-O 3.29Å; Y338-N340 HydrophobicContact CE1-CB 3.94Å; Y338-N340 WeakPolarHBondContact CE1-O 3.45Å; Y338-N340 PolarHBondContact O-N 3.26Å; N340-S342 PolarHBondContact O-N 3.32Å; N340-S342 PolarHBondContact OD1-N 3.07Å; N340-S342 VanDerWaalsContact OD1-N 3.16Å; N340-D343 PolarHBondContact O-N 3.33Å
341T89.5Confident94.9Very high78 Ų7844.3 Ų44.348%0.47924%0.244SC..THydrogen-bonded Turntrans-67.7-5.2-177.258.10000114.9L354T341-L354 HydrophobicContact CG2-CB 4.11Å
342S90.1Very high95Very high81 Ų8139.4 Ų39.457%0.56622%0.218SC*.THydrogen-bonded Turntrans-110.313.3-178.7-58.90000112.9N340 N347N340-S342 PolarHBondContact O-N 3.32Å; N340-S342 PolarHBondContact OD1-N 3.07Å; N340-S342 VanDerWaalsContact OD1-N 3.16Å; S342-N347 PolarHBondContact O-ND2 2.96Å
343D91.9Very high94.9Very high15 Ų1541.2 Ų41.28%0.0823%0.227CC..  trans-58.3120.1-176.4-164.6-44.8000112.3Y338 N340 I345 V346 N347Y338-D343 HydrophobicContact CE1-CB 3.72Å; Y338-D343 WeakPolarHBondContact CE1-OD2 3.44Å; Y338-D343 PolarHBondContact OH-OD2 3.42Å; N340-D343 PolarHBondContact O-N 3.33Å; D343-I345 PolarHBondContact O-N 2.91Å; D343-I345 VanDerWaalsContact O-N 3.12Å; D343-I345 WeakPolarHBondContact OD1-CB 3.29Å; D343-I345 VanDerWaalsContact OD1-CG1 3.32Å; D343-I345 WeakPolarHBondContact OD1-CG1 3.07Å; D343-I345 PolarHBondContact OD1-N 3.3Å; D343-V346 PolarHBondContact O-N 3.07Å; D343-N347 WeakPolarHBondContact O-CB 3.34Å; D343-N347 PolarHBondContact O-N 3.14Å
344P92.4Very high94.8Very high93 Ų9342.3 Ų42.360%0.60423%0.232SC*.THydrogen-bonded Turntrans-61.8-20.2-176.626.5-35.5000114V346 H348P344-V346 VanDerWaalsContact C-N 3.26Å; P344-V346 PolarHBondContact O-N 3.05Å; P344-H348 PolarHBondContact O-CE1 3.48Å; P344-H348 PolarHBondContact O-ND1 2.92Å
345I92.4Very high94.6Very high36 Ų3642.8 Ų42.819%0.18524%0.237CC..THydrogen-bonded Turntrans-62.1-35.1178.9-63.3174.2000111.1K319 A323 D343 H348K319-I345 HydrophobicContact CB-CD1 3.91Å; K319-I345 HydrophobicContact CB-CG2 4.29Å; K319-I345 HydrophobicContact CD-CD1 3.85Å; A323-I345 HydrophobicContact CB-CG2 3.79Å; D343-I345 PolarHBondContact O-N 2.91Å; D343-I345 VanDerWaalsContact O-N 3.12Å; D343-I345 WeakPolarHBondContact OD1-CB 3.29Å; D343-I345 VanDerWaalsContact OD1-CG1 3.32Å; D343-I345 WeakPolarHBondContact OD1-CG1 3.07Å; D343-I345 PolarHBondContact OD1-N 3.3Å; I345-H348 PolarHBondContact O-CE1 2.93Å
346V93.5Very high94.3Very high2 Ų247.1 Ų47.11%0.01226%0.26CS..THydrogen-bonded Turntrans-131.8-14.3-174-60.40000115.2A323 F326 W336 D343 P344 H348 L349 V352 L354A323-V346 HydrophobicContact CB-CG1 3.88Å; F326-V346 HydrophobicContact CD2-CG1 4.21Å; F326-V346 HydrophobicContact CE2-CG1 4.24Å; W336-V346 HydrophobicContact CZ3-CG1 4.09Å; W336-V346 HydrophobicContact CZ3-CG2 4.48Å; D343-V346 PolarHBondContact O-N 3.07Å; P344-V346 VanDerWaalsContact C-N 3.26Å; P344-V346 PolarHBondContact O-N 3.05Å; V346-H348 PolarHBondContact O-N 3.41Å; V346-L349 HydrophobicContact CB-CD1 4.37Å; V346-L349 HydrophobicContact CG1-CD1 4.41Å; V346-L349 WeakPolarHBondContact O-CB 3.41Å; V346-L349 PolarHBondContact O-N 3.25Å; V346-V352 HydrophobicContact CB-CG1 4.2Å; V346-V352 HydrophobicContact CG2-CG1 4.31Å; V346-L354 HydrophobicContact CG2-CD1 3.73Å; V346-L354 HydrophobicContact CG2-CD2 3.98Å; V346-L354 HydrophobicContact CG2-CG 4.21Å
347N89.3Confident93.9Very high91 Ų9156.5 Ų56.549%0.48730%0.296SS..THydrogen-bonded Turntrans-60.9-18.4-175.369.13.8000114.4S342 D343S342-N347 PolarHBondContact O-ND2 2.96Å; D343-N347 WeakPolarHBondContact O-CB 3.34Å; D343-N347 PolarHBondContact O-N 3.14Å
348H92.7Very high93.8Very high127 Ų12756.3 Ų56.359%0.58830%0.295SS*.THydrogen-bonded Turntrans-88.8-6.6179.264.9-88.1000113.1P344 I345 V346P344-H348 PolarHBondContact O-CE1 3.48Å; P344-H348 PolarHBondContact O-ND1 2.92Å; I345-H348 PolarHBondContact O-CE1 2.93Å; V346-H348 PolarHBondContact O-N 3.41Å
349L96.7Very high93.8Very high22 Ų2257.5 Ų57.512%0.11530%0.304CS..  trans-91117.9179.6-58.9176.2000110.2A323 F326 K327 V346 N351 V352A323-L349 HydrophobicContact CB-CD1 4.45Å; F326-L349 HydrophobicContact CB-CD1 4.01Å; F326-L349 HydrophobicContact CD2-CD1 4.38Å; K327-L349 HydrophobicContact CB-CD2 4.4Å; V346-L349 HydrophobicContact CB-CD1 4.37Å; V346-L349 HydrophobicContact CG1-CD1 4.41Å; V346-L349 WeakPolarHBondContact O-CB 3.41Å; V346-L349 PolarHBondContact O-N 3.25Å; L349-N351 PolarHBondContact O-N 3.48Å; L349-V352 HydrophobicContact CB-CB 4.19Å; L349-V352 HydrophobicContact CB-CG2 3.71Å; L349-V352 HydrophobicContact CD1-CG2 3.93Å; L349-V352 HydrophobicContact CG-CG2 4.48Å; L349-V352 PolarHBondContact O-N 3.33Å
350D96.3Very high93.8Very high124 Ų12457 Ų5766%0.66330%0.301SS*.THydrogen-bonded Turntrans-73.1-11.5-176.375.8-31.8000114.1R297R297-D350 PolarHBondContact NH1-O 3.44Å; R297-D350 VanDerWaalsContact NH2-CG 3.28Å; R297-D350 PolarHBondContact NH2-O 3.01Å; R297-D350 VanDerWaalsContact NH2-O 3.16Å; R297-D350 IonicContact NH2-OD1 2.72Å; R297-D350 PolarHBondContact NH2-OD1 3.19Å; R297-D350 IonicContact NH2-OD2 3.73Å; R297-D350 PolarHBondContact NH2-OD2 2.82Å
351N98.2Very high93.8Very high4 Ų454.4 Ų54.42%0.02129%0.287CS..THydrogen-bonded Turntrans-98.13.2175.673.3-32.5000113.8F326 M329 T332 F334 L349F326-N351 PolarHBondContact O-ND2 3.48Å; M329-N351 PolarHBondContact O-ND2 2.92Å; T332-N351 WeakPolarHBondContact O-CB 3.33Å; T332-N351 PolarHBondContact O-ND2 3.26Å; T332-N351 VanDerWaalsContact O-ND2 3.12Å; F334-N351 PolarHBondContact N-O 2.68Å; L349-N351 PolarHBondContact O-N 3.48Å
352V98.2Very high94.1Very high15 Ų1552.6 Ų52.69%0.09127%0.273CS..EExtended strand (participates in β ladder)trans-112.6128.1178-174.40000110F326 F334 V346 L349 L354F326-V352 HydrophobicContact CB-CG2 3.75Å; F326-V352 HydrophobicContact CD2-CG1 4.37Å; F326-V352 HydrophobicContact CD2-CG2 3.44Å; F326-V352 VanDerWaalsContact CD2-CG2 3.44Å; F326-V352 HydrophobicContact CE2-CG1 4.4Å; F326-V352 HydrophobicContact CE2-CG2 4.24Å; F326-V352 HydrophobicContact CG-CG2 3.76Å; F334-V352 HydrophobicContact CB-CG2 4.4Å; F334-V352 CarbonylContact O-C 3.58Å; F334-V352 WeakPolarHBondContact O-CA 3.29Å; V346-V352 HydrophobicContact CB-CG1 4.2Å; V346-V352 HydrophobicContact CG2-CG1 4.31Å; L349-V352 HydrophobicContact CB-CB 4.19Å; L349-V352 HydrophobicContact CB-CG2 3.71Å; L349-V352 HydrophobicContact CD1-CG2 3.93Å; L349-V352 HydrophobicContact CG-CG2 4.48Å; L349-V352 PolarHBondContact O-N 3.33Å; V352-L354 HydrophobicContact CG1-CD2 3.8Å; V352-L354 HydrophobicContact CG1-CG 4.48Å
353H97.3Very high94.4Very high43 Ų4348.7 Ų48.720%0.19925%0.246CC..EExtended strand (participates in β ladder)trans-123.2111.8177.5-57.3-78.9000110W290 I293 F334 I335 W336W290-H353 HydrophobicContact CZ3-CB 3.99Å; I293-H353 HydrophobicContact CD1-CB 4.24Å; I293-H353 WeakPolarHBondContact CG2-CD2 3.29Å; F334-H353 PolarHBondContact O-N 2.82Å; I335-H353 WeakPolarHBondContact CA-O 3.38Å; W336-H353 PolarHBondContact N-O 3.01Å
354L96.8Very high94.7Very high23 Ų2348.1 Ų48.112%0.1224%0.243CC..EExtended strand (participates in β ladder)trans-88.8150.5179.9-55.9-173.2000112.1W336 Y338 T341 V346 V352W336-L354 HydrophobicContact CB-CD2 3.93Å; W336-L354 HydrophobicContact CD2-CD2 4.42Å; W336-L354 HydrophobicContact CE3-CD2 4.01Å; W336-L354 HydrophobicContact CG-CD2 4.43Å; W336-L354 WeakPolarHBondContact O-CA 3.29Å; Y338-L354 HydrophobicContact CD1-CD1 4.06Å; Y338-L354 HydrophobicContact CG-CD1 4.42Å; Y338-L354 HydrophobicContact CG-CD2 4.31Å; T341-L354 HydrophobicContact CG2-CB 4.11Å; V346-L354 HydrophobicContact CG2-CD1 3.73Å; V346-L354 HydrophobicContact CG2-CD2 3.98Å; V346-L354 HydrophobicContact CG2-CG 4.21Å; V352-L354 HydrophobicContact CG1-CD2 3.8Å; V352-L354 HydrophobicContact CG1-CG 4.48Å
355G94.1Very high94.8Very high9 Ų944.6 Ų44.69%0.09322%0.221CC..EExtended strand (participates in β ladder)trans-163140.116700000112.2W336 K337 Y338W336-G355 PolarHBondContact O-N 3.29Å; K337-G355 CarbonylContact C-O 3.57Å; K337-G355 VanDerWaalsContact CA-O 3.27Å; K337-G355 WeakPolarHBondContact CA-O 3.5Å; Y338-G355 PolarHBondContact N-O 3.26Å; Y338-G355 CarbonylContact O-C 3.6Å
356D91Very high94.9Very high92 Ų9243.9 Ų43.949%0.49222%0.218SC..SBendtrans-68.7-43.8177.9177.934.4000111.7K337 Y338K337-D356 WeakPolarHBondContact CE-O 3.49Å; Y338-D356 PolarHBondContact O-N 3.14Å
357W91Very high95Very high199 Ų19949.9 Ų49.975%0.75426%0.257SS*.SBendtrans-122.8123.7175.2-166.5-97000110.8
358L95.1Very high95.4Very high13 Ų1349.6 Ų49.67%0.06825%0.249CC..  trans-121.9146.7-174.6-65.4176.2000111.2W290 F302 I335 K337 Q360 L363W290-L358 HydrophobicContact CH2-CD2 3.29Å; W290-L358 HydrophobicContact CZ2-CD2 3.11Å; W290-L358 HydrophobicContact CZ3-CD2 4.1Å; F302-L358 HydrophobicContact CD2-CD1 4.35Å; F302-L358 HydrophobicContact CE2-CB 4.27Å; F302-L358 HydrophobicContact CE2-CD1 3.55Å; F302-L358 HydrophobicContact CZ-CB 4.45Å; F302-L358 HydrophobicContact CZ-CD1 4.41Å; I335-L358 HydrophobicContact CG2-CD1 3.73Å; I335-L358 HydrophobicContact CG2-CD2 4.25Å; K337-L358 HydrophobicContact CB-CD1 3.86Å; K337-L358 HydrophobicContact CG-CD1 4.5Å; L358-Q360 PolarHBondContact O-N 3.08Å; L358-L363 HydrophobicContact CB-CD1 4.49Å
359P94.8Very high95.6Very high28 Ų2844.2 Ų44.218%0.18223%0.225CC..  trans-7769.2177.834.4-36.3000110.4L286 W290 N361 E362 L363L286-P359 HydrophobicContact CD1-CB 4.35Å; L286-P359 HydrophobicContact CD1-CG 3.66Å; W290-P359 VanDerWaalsContact CD1-CG 3.49Å; W290-P359 HydrophobicContact CG-CG 4.25Å; P359-N361 PolarHBondContact O-N 2.85Å; P359-E362 HydrophobicContact CB-CB 4.16Å; P359-E362 HydrophobicContact CB-CG 4.42Å; P359-E362 WeakPolarHBondContact CB-OE2 3.38Å; P359-E362 PolarHBondContact O-N 3.38Å; P359-L363 HydrophobicContact CG-CG 4.42Å; P359-L363 WeakPolarHBondContact O-CG 3.31Å; P359-L363 PolarHBondContact O-N 2.97Å
360Q95.1Very high95.7Very high33 Ų3344.3 Ų44.315%0.15423%0.227CC..Hα-helixtrans-54.6-46.7-171.9163.3163-48.500112.5F302 L358 E362 L363 L364 S380 E383F302-Q360 HydrophobicContact CE1-CB 3.84Å; F302-Q360 HydrophobicContact CE1-CG 3.71Å; F302-Q360 HydrophobicContact CZ-CB 4.03Å; F302-Q360 HydrophobicContact CZ-CG 4.33Å; L358-Q360 PolarHBondContact O-N 3.08Å; Q360-E362 VanDerWaalsContact C-N 3.34Å; Q360-E362 PolarHBondContact O-N 3.12Å; Q360-L363 PolarHBondContact O-N 3.27Å; Q360-L364 HydrophobicContact CG-CD1 3.77Å; Q360-L364 HydrophobicContact CG-CG 4.36Å; Q360-L364 WeakPolarHBondContact O-CB 3.26Å; Q360-L364 VanDerWaalsContact O-CG 3.22Å; Q360-L364 WeakPolarHBondContact O-CG 3.43Å; Q360-L364 PolarHBondContact O-N 2.62Å; Q360-S380 PolarHBondContact NE2-OG 2.86Å; Q360-E383 PolarHBondContact NE2-OE2 3.32Å
361N93.6Very high95.8Very high15 Ų1538.4 Ų38.48%0.0820%0.196CC..Hα-helixtrans-69.4-35.9-175.6-161.634.2000111.7K278 L284 P359 A365K278-N361 PolarHBondContact O-ND2 3.33Å; L284-N361 WeakPolarHBondContact CD1-ND2 3.24Å; L284-N361 WeakPolarHBondContact CD2-ND2 3.37Å; P359-N361 PolarHBondContact O-N 2.85Å; N361-A365 WeakPolarHBondContact O-CB 3.48Å; N361-A365 PolarHBondContact O-N 2.92Å
362E95.8Very high95.9Very high39 Ų3938.2 Ų38.218%0.18220%0.195CC..Hα-helixtrans-68.9-39.3174.1-62.872.3-166.300111.8L284 L286 P359 Q360 A365 D366L284-E362 HydrophobicContact CB-CG 4.22Å; L284-E362 HydrophobicContact CD2-CG 4.41Å; L286-E362 HydrophobicContact CB-CB 4.43Å; L286-E362 HydrophobicContact CD1-CB 3.9Å; P359-E362 HydrophobicContact CB-CB 4.16Å; P359-E362 HydrophobicContact CB-CG 4.42Å; P359-E362 WeakPolarHBondContact CB-OE2 3.38Å; P359-E362 PolarHBondContact O-N 3.38Å; Q360-E362 VanDerWaalsContact C-N 3.34Å; Q360-E362 PolarHBondContact O-N 3.12Å; E362-A365 PolarHBondContact O-N 3.47Å; E362-D366 PolarHBondContact O-N 2.93Å
363L97.2Very high95.9Very high0 Ų037.6 Ų37.60%019%0.191CC..Hα-helixtrans-62.7-45.2173-74.6169.7000111.5L286 W290 L294 F302 I335 L358 P359 Q360 A365 D366 L369L286-L363 HydrophobicContact CD1-CD2 3.88Å; L286-L363 HydrophobicContact CD1-CG 4.02Å; L286-L363 HydrophobicContact CD2-CD2 4.02Å; W290-L363 HydrophobicContact CB-CD2 4.44Å; L294-L363 HydrophobicContact CD1-CD2 4.1Å; L294-L363 HydrophobicContact CD2-CD2 4.48Å; L294-L363 HydrophobicContact CG-CD2 4.48Å; F302-L363 HydrophobicContact CD1-CD1 4.43Å; F302-L363 HydrophobicContact CD2-CD1 3.94Å; F302-L363 HydrophobicContact CE2-CD1 4.07Å; F302-L363 HydrophobicContact CG-CD1 4.17Å; F302-L363 HydrophobicContact CZ-CD1 4.34Å; I335-L363 HydrophobicContact CD1-CD2 3.81Å; I335-L363 HydrophobicContact CG2-CD1 4.24Å; L358-L363 HydrophobicContact CB-CD1 4.49Å; P359-L363 HydrophobicContact CG-CG 4.42Å; P359-L363 WeakPolarHBondContact O-CG 3.31Å; P359-L363 PolarHBondContact O-N 2.97Å; Q360-L363 PolarHBondContact O-N 3.27Å; L363-A365 VanDerWaalsContact C-N 3.28Å; L363-A365 PolarHBondContact O-N 3.29Å; L363-D366 PolarHBondContact O-N 3.44Å; L363-L369 WeakPolarHBondContact O-CD2 3.29Å
364L96.8Very high95.9Very high3 Ų335.6 Ų35.62%0.01618%0.182CC..Hα-helixtrans-64.4-33.4177.8-69.6171.9000112.3Q360 D366 L369 F372 E383 L384 M387 T389Q360-L364 HydrophobicContact CG-CD1 3.77Å; Q360-L364 HydrophobicContact CG-CG 4.36Å; Q360-L364 WeakPolarHBondContact O-CB 3.26Å; Q360-L364 VanDerWaalsContact O-CG 3.22Å; Q360-L364 WeakPolarHBondContact O-CG 3.43Å; Q360-L364 PolarHBondContact O-N 2.62Å; L364-D366 VanDerWaalsContact C-N 3.31Å; L364-L369 HydrophobicContact CD2-CD2 3.9Å; L364-F372 HydrophobicContact CD1-CD1 4.37Å; L364-F372 HydrophobicContact CD1-CE1 4.27Å; L364-F372 HydrophobicContact CD2-CB 3.95Å; L364-F372 HydrophobicContact CD2-CD1 3.59Å; L364-F372 HydrophobicContact CD2-CE1 4.23Å; L364-F372 HydrophobicContact CD2-CG 3.89Å; L364-E383 HydrophobicContact CD1-CB 3.77Å; L364-L384 HydrophobicContact CD1-CB 4.2Å; L364-L384 HydrophobicContact CD2-CB 3.93Å; L364-M387 HydrophobicContact CB-CB 4.1Å; L364-M387 HydrophobicContact CB-CG 3.91Å; L364-M387 WeakPolarHBondContact O-CB 3.37Å; L364-T389 HydrophobicContact CD2-CG2 4.06Å; L364-T389 PolarHBondContact O-OG1 3.1Å
365A94.3Very high95.9Very high18 Ų1835.4 Ų35.415%0.14918%0.18CC..Hα-helixtrans-75.1-16.7176.800000113.9L284 N361 E362 L363 M387L284-A365 HydrophobicContact CB-CB 4.01Å; L284-A365 HydrophobicContact CD1-CB 3.77Å; N361-A365 WeakPolarHBondContact O-CB 3.48Å; N361-A365 PolarHBondContact O-N 2.92Å; E362-A365 PolarHBondContact O-N 3.47Å; L363-A365 VanDerWaalsContact C-N 3.28Å; L363-A365 PolarHBondContact O-N 3.29Å; A365-M387 HydrophobicContact CB-CG 4.48Å; A365-M387 HydrophobicContact CB-SD 3.73Å
366D95.6Very high96.1Very high22 Ų2235 Ų3512%0.11818%0.176CC..  trans-79.2125.4-176.8-164.3-61.7000111.3L294 E362 L363 L364 R368 L369L294-D366 HydrophobicContact CD1-CB 3.95Å; E362-D366 PolarHBondContact O-N 2.93Å; L363-D366 PolarHBondContact O-N 3.44Å; L364-D366 VanDerWaalsContact C-N 3.31Å; D366-R368 PolarHBondContact O-N 3.39Å; D366-R368 VanDerWaalsContact O-N 3.08Å; D366-R368 VanDerWaalsContact OD1-CB 3.24Å; D366-R368 WeakPolarHBondContact OD1-CB 3.28Å; D366-R368 WeakPolarHBondContact OD1-CG 3.24Å; D366-R368 IonicContact OD1-CZ 3.37Å; D366-R368 PolarHBondContact OD1-N 2.85Å; D366-R368 IonicContact OD1-NE 3.49Å; D366-R368 PolarHBondContact OD1-NE 3.22Å; D366-R368 IonicContact OD1-NH2 3.81Å; D366-R368 IonicContact OD2-CZ 3.32Å; D366-R368 IonicContact OD2-NE 3.65Å; D366-R368 PolarHBondContact OD2-NE 2.95Å; D366-R368 IonicContact OD2-NH2 2.98Å; D366-R368 PolarHBondContact OD2-NH2 2.95Å; D366-L369 PolarHBondContact O-N 3.39Å; D366-L369 VanDerWaalsContact O-N 3.13Å
367P94.8Very high96.3Very high128 Ų12831.1 Ų31.183%0.83116%0.158SC*.THydrogen-bonded Turntrans-66.1-12-177.728-36.4000114.3
368R97.3Very high96.5Very high85 Ų8522.2 Ų22.232%0.32113%0.125SC..THydrogen-bonded Turntrans-83.3-13.4176.9-62.1169.8-72.1176.2-2.5112.9S291 L294 N300 D366 S370S291-R368 PolarHBondContact O-NH1 3.47Å; S291-R368 PolarHBondContact OG-NH2 2.93Å; L294-R368 HydrophobicContact CB-CB 4.34Å; N300-R368 PolarHBondContact ND2-O 3.2Å; D366-R368 PolarHBondContact O-N 3.39Å; D366-R368 VanDerWaalsContact O-N 3.08Å; D366-R368 VanDerWaalsContact OD1-CB 3.24Å; D366-R368 WeakPolarHBondContact OD1-CB 3.28Å; D366-R368 WeakPolarHBondContact OD1-CG 3.24Å; D366-R368 IonicContact OD1-CZ 3.37Å; D366-R368 PolarHBondContact OD1-N 2.85Å; D366-R368 IonicContact OD1-NE 3.49Å; D366-R368 PolarHBondContact OD1-NE 3.22Å; D366-R368 IonicContact OD1-NH2 3.81Å; D366-R368 IonicContact OD2-CZ 3.32Å; D366-R368 IonicContact OD2-NE 3.65Å; D366-R368 PolarHBondContact OD2-NE 2.95Å; D366-R368 IonicContact OD2-NH2 2.98Å; D366-R368 PolarHBondContact OD2-NH2 2.95Å; R368-S370 PolarHBondContact O-N 2.8Å
369L98.3Very high96.4Very high13 Ų1323 Ų237%0.06814%0.137CC..  trans-71.7124.7174.7-174.967.4000110N300 F302 L363 L364 D366 T389N300-L369 HydrophobicContact CB-CD1 4.34Å; F302-L369 HydrophobicContact CB-CD1 3.65Å; F302-L369 HydrophobicContact CB-CD2 4.21Å; L363-L369 WeakPolarHBondContact O-CD2 3.29Å; L364-L369 HydrophobicContact CD2-CD2 3.9Å; D366-L369 PolarHBondContact O-N 3.39Å; D366-L369 VanDerWaalsContact O-N 3.13Å; L369-T389 HydrophobicContact CD2-CG2 3.77Å; L369-T389 HydrophobicContact CG-CG2 4.18Å
370S98.5Very high96.4Very high25 Ų2522.3 Ų22.318%0.17513%0.132CC..  trans-89.8-47.5-176.6-46.70000112.2N299 N300 R368 P390N299-S370 WeakPolarHBondContact CA-OG 3.36Å; N300-S370 PolarHBondContact N-OG 3Å; N300-S370 WeakPolarHBondContact O-CA 3.28Å; N300-S370 VanDerWaalsContact O-CB 3.26Å; N300-S370 WeakPolarHBondContact O-CB 3.49Å; N300-S370 PolarHBondContact O-N 3.35Å; N300-S370 PolarHBondContact O-OG 3.35Å; R368-S370 PolarHBondContact O-N 2.8Å; S370-P390 WeakPolarHBondContact O-CD 3.4Å
371V98.7Very high96.5Very high0 Ų020.7 Ų20.70%013%0.125CC..EExtended strand (participates in β ladder)trans-146.8143.7-175.2178.90000110.6N300 V301 F302 P390 V392 L431 V434 I435N300-V371 PolarHBondContact O-N 3.33Å; V301-V371 WeakPolarHBondContact CA-O 3.43Å; F302-V371 PolarHBondContact N-O 3.14Å; V371-P390 WeakPolarHBondContact CA-O 3.3Å; V371-P390 HydrophobicContact CG2-CB 4.42Å; V371-V392 HydrophobicContact CG1-CG2 4.03Å; V371-L431 HydrophobicContact CG1-CD2 4.31Å; V371-V434 HydrophobicContact CG1-CG1 4.1Å; V371-V434 HydrophobicContact CG2-CB 4.07Å; V371-V434 HydrophobicContact CG2-CG1 3.6Å; V371-I435 HydrophobicContact CG2-CG1 3.54Å
372F98.8Very high96.6Very high0 Ų020.2 Ų20.20%012%0.122CC..EExtended strand (participates in β ladder)trans-107121167.1-175.6-157.3000111.3F302 L364 T374 L384 T389 P390 A391 V392F302-F372 HydrophobicContact CB-CD2 4.12Å; F302-F372 AromaticContact CD1-CD2 3.33Å; F302-F372 HydrophobicContact CD1-CD2 3.33Å; F302-F372 AromaticContact CD1-CE2 3.26Å; F302-F372 HydrophobicContact CD1-CE2 3.26Å; F302-F372 HydrophobicContact CD1-CG 4.1Å; F302-F372 AromaticContact CD1-CZ 3.95Å; F302-F372 HydrophobicContact CD1-CZ 3.95Å; F302-F372 AromaticContact CE1-CD2 3.89Å; F302-F372 HydrophobicContact CE1-CD2 3.89Å; F302-F372 HydrophobicContact CE1-CE1 4.47Å; F302-F372 AromaticContact CE1-CE2 3.29Å; F302-F372 HydrophobicContact CE1-CE2 3.29Å; F302-F372 AromaticContact CE1-CZ 3.63Å; F302-F372 HydrophobicContact CE1-CZ 3.63Å; F302-F372 AromaticContact CG-CD2 3.91Å; F302-F372 HydrophobicContact CG-CD2 3.91Å; F302-F372 HydrophobicContact CG-CE2 4.02Å; F302-F372 HydrophobicContact CZ-CE2 4.07Å; F302-F372 HydrophobicContact CZ-CZ 4.48Å; F302-F372 CarbonylContact O-C 3.4Å; F302-F372 WeakPolarHBondContact O-CA 3.32Å; F302-F372 WeakPolarHBondContact O-CD2 3.26Å; L364-F372 HydrophobicContact CD1-CD1 4.37Å; L364-F372 HydrophobicContact CD1-CE1 4.27Å; L364-F372 HydrophobicContact CD2-CB 3.95Å; L364-F372 HydrophobicContact CD2-CD1 3.59Å; L364-F372 HydrophobicContact CD2-CE1 4.23Å; L364-F372 HydrophobicContact CD2-CG 3.89Å; F372-T374 HydrophobicContact CD1-CG2 4.05Å; F372-T374 HydrophobicContact CE1-CG2 3.94Å; F372-T374 HydrophobicContact CZ-CG2 4.26Å; F372-L384 HydrophobicContact CD1-CB 4.09Å; F372-L384 HydrophobicContact CD1-CD2 3.67Å; F372-L384 HydrophobicContact CE1-CD2 4.24Å; F372-T389 HydrophobicContact CB-CG2 4.24Å; F372-P390 PolarHBondContact N-O 3.37Å; F372-A391 CarbonylContact O-C 3.48Å; F372-A391 WeakPolarHBondContact O-CA 3.37Å; F372-A391 WeakPolarHBondContact O-CB 3.44Å; F372-V392 PolarHBondContact O-N 2.84Å
373V98.8Very high96.6Very high2 Ų218.9 Ų18.91%0.01212%0.116CC..EExtended strand (participates in β ladder)trans-94.7120.1170.8-174.30000108.7V301 F302 I303 S304 F305 V392 I394 L431V301-V373 HydrophobicContact CG1-CG2 3.75Å; F302-V373 PolarHBondContact O-N 2.98Å; I303-V373 WeakPolarHBondContact CA-O 3.21Å; I303-V373 HydrophobicContact CB-CB 4.33Å; I303-V373 HydrophobicContact CG1-CB 4.03Å; I303-V373 HydrophobicContact CG1-CG2 4.15Å; I303-V373 HydrophobicContact CG2-CB 4.15Å; I303-V373 HydrophobicContact CG2-CG1 4.28Å; S304-V373 PolarHBondContact N-O 3.17Å; F305-V373 HydrophobicContact CZ-CG1 4.34Å; V373-V392 VanDerWaalsContact CA-O 3.31Å; V373-V392 WeakPolarHBondContact CA-O 3.43Å; V373-V392 HydrophobicContact CG2-CB 4.26Å; V373-I394 HydrophobicContact CG1-CD1 3.66Å; V373-I394 HydrophobicContact CG1-CG1 4.26Å; V373-L431 HydrophobicContact CG2-CD2 3.75Å
374T98.4Very high96.6Very high0 Ų018.9 Ų18.90%012%0.116CC..EExtended strand (participates in β ladder)trans-151.2159.2-175.9-168.60000113.2S304 F372 G376 L384 V392 M393 I394S304-T374 VanDerWaalsContact O-CA 3.25Å; S304-T374 WeakPolarHBondContact O-CA 2.87Å; S304-T374 VanDerWaalsContact O-CB 3.3Å; S304-T374 WeakPolarHBondContact O-CB 3.17Å; S304-T374 PolarHBondContact O-OG1 3.21Å; F372-T374 HydrophobicContact CD1-CG2 4.05Å; F372-T374 HydrophobicContact CE1-CG2 3.94Å; F372-T374 HydrophobicContact CZ-CG2 4.26Å; T374-G376 PolarHBondContact O-N 2.99Å; T374-L384 HydrophobicContact CG2-CD2 4.23Å; T374-V392 PolarHBondContact N-O 3.13Å; T374-M393 HydrophobicContact CG2-CE 3.82Å; T374-M393 HydrophobicContact CG2-SD 3.55Å; T374-M393 VanDerWaalsContact CG2-SD 3.55Å; T374-M393 CarbonylContact O-C 3.6Å; T374-M393 VanDerWaalsContact O-CA 3.31Å; T374-M393 WeakPolarHBondContact O-CA 3.46Å; T374-I394 PolarHBondContact O-N 2.56Å
375H96.9Very high96.6Very high19 Ų1918.9 Ų18.99%0.08812%0.116CC..  trans-68-24.5175.366.5-79.6000113.3F305 G306 G377 I394 P395 L396 Q400F305-H375 WeakPolarHBondContact CA-ND1 3.49Å; F305-H375 HydrophobicContact CD1-CB 4.02Å; F305-H375 PolarHBondContact O-CE1 2.8Å; F305-H375 PolarHBondContact O-ND1 3.37Å; G306-H375 PolarHBondContact N-ND1 2.96Å; H375-G377 PolarHBondContact CD2-N 3.33Å; H375-G377 VanDerWaalsContact NE2-CA 3.27Å; H375-G377 WeakPolarHBondContact NE2-CA 3.41Å; H375-G377 PolarHBondContact NE2-N 3.05Å; H375-I394 VanDerWaalsContact CA-O 3.25Å; H375-I394 WeakPolarHBondContact CA-O 3.34Å; H375-P395 WeakPolarHBondContact O-CA 3.4Å; H375-L396 HydrophobicContact CB-CD1 4.16Å; H375-L396 HydrophobicContact CB-CG 4.22Å; H375-Q400 PolarHBondContact CD2-NE2 3.05Å; H375-Q400 VanDerWaalsContact CD2-NE2 3.33Å; H375-Q400 WeakPolarHBondContact O-CB 3.33Å
376G96.5Very high96.6Very high0 Ų018.7 Ų18.70%011%0.112CC..  trans92.630.6179.600000116.4T374 N403T374-G376 PolarHBondContact O-N 2.99Å; G376-N403 WeakPolarHBondContact O-CB 3.47Å; G376-N403 PolarHBondContact O-ND2 3.14Å
377G95.3Very high96.6Very high12 Ų1218.1 Ų18.112%0.12411%0.109CC..  trans-59143164.800000111.1H375 G379 S380 V381H375-G377 PolarHBondContact CD2-N 3.33Å; H375-G377 VanDerWaalsContact NE2-CA 3.27Å; H375-G377 WeakPolarHBondContact NE2-CA 3.41Å; H375-G377 PolarHBondContact NE2-N 3.05Å; G377-G379 PolarHBondContact O-N 2.95Å; G377-G379 VanDerWaalsContact O-N 3.15Å; G377-S380 PolarHBondContact O-N 3.09Å; G377-V381 PolarHBondContact O-N 2.8Å
378L95.5Very high96.7Very high12 Ų1212.3 Ų12.36%0.0637%0.072CC..Hα-helixtrans-55.6-37.3-171.6-176.355.6000113.6N172 N254 V381 T382 N403 M406N172-L378 VanDerWaalsContact ND2-CD1 3.28Å; N172-L378 WeakPolarHBondContact ND2-CD1 3.42Å; N254-L378 HydrophobicContact CB-CD2 4.17Å; L378-V381 PolarHBondContact O-N 3.16Å; L378-T382 WeakPolarHBondContact O-CB 3.21Å; L378-T382 PolarHBondContact O-N 3.11Å; L378-T382 PolarHBondContact O-OG1 2.63Å; L378-N403 PolarHBondContact N-ND2 3.39Å; L378-M406 HydrophobicContact CD1-CE 4.16Å
379G93.7Very high96.8Very high30 Ų308.6 Ų8.631%0.3096%0.059SC..Hα-helixtrans-59.5-51.7175.600000112.5G377 V381 T382 E383G377-G379 PolarHBondContact O-N 2.95Å; G377-G379 VanDerWaalsContact O-N 3.15Å; G379-V381 PolarHBondContact O-N 3.48Å; G379-T382 PolarHBondContact O-N 2.76Å; G379-E383 VanDerWaalsContact O-CG 3.31Å; G379-E383 WeakPolarHBondContact O-CG 3.26Å; G379-E383 PolarHBondContact O-N 2.83Å
380S95.3Very high96.8Very high12 Ų128.1 Ų8.18%0.0846%0.057CC..Hα-helixtrans-62-41.7177-67.10000112Q360 G377 T382 E383 L384Q360-S380 PolarHBondContact NE2-OG 2.86Å; G377-S380 PolarHBondContact O-N 3.09Å; S380-T382 VanDerWaalsContact C-N 3.32Å; S380-T382 PolarHBondContact O-N 3.02Å; S380-E383 PolarHBondContact O-N 3.27Å; S380-L384 WeakPolarHBondContact O-CB 3.3Å; S380-L384 WeakPolarHBondContact O-CD2 3.48Å; S380-L384 VanDerWaalsContact O-CG 3.26Å; S380-L384 WeakPolarHBondContact O-CG 3.37Å; S380-L384 PolarHBondContact O-N 3.47Å
381V97Very high96.8Very high0 Ų06.9 Ų6.90%05%0.049CC..Hα-helixtrans-61.8-41.9177.1171.20000111.2L259 G377 L378 G379 A385 M393 N403 M406 L407L259-V381 HydrophobicContact CD2-CG1 4.4Å; G377-V381 PolarHBondContact O-N 2.8Å; L378-V381 PolarHBondContact O-N 3.16Å; G379-V381 PolarHBondContact O-N 3.48Å; V381-A385 WeakPolarHBondContact O-CB 3.46Å; V381-A385 PolarHBondContact O-N 2.97Å; V381-M393 HydrophobicContact CG2-CE 3.43Å; V381-M393 VanDerWaalsContact CG2-CE 3.43Å; V381-N403 HydrophobicContact CG2-CB 4.23Å; V381-M406 HydrophobicContact CG1-CE 3.43Å; V381-M406 VanDerWaalsContact CG1-CE 3.43Å; V381-L407 HydrophobicContact CG1-CB 4.16Å; V381-L407 HydrophobicContact CG1-CD2 4.49Å
382T96.2Very high96.8Very high4 Ų46.9 Ų6.93%0.0255%0.049CC..Hα-helixtrans-67.7-46.3177.7-51.60000111I256 V277 L378 G379 S380 A385 M386I256-T382 HydrophobicContact CD1-CG2 3.67Å; V277-T382 HydrophobicContact CG2-CG2 3.7Å; L378-T382 WeakPolarHBondContact O-CB 3.21Å; L378-T382 PolarHBondContact O-N 3.11Å; L378-T382 PolarHBondContact O-OG1 2.63Å; G379-T382 PolarHBondContact O-N 2.76Å; S380-T382 VanDerWaalsContact C-N 3.32Å; S380-T382 PolarHBondContact O-N 3.02Å; T382-A385 PolarHBondContact O-N 2.98Å; T382-M386 HydrophobicContact CG2-CG 4.38Å; T382-M386 HydrophobicContact CG2-SD 3.96Å; T382-M386 WeakPolarHBondContact O-CB 3.34Å; T382-M386 VanDerWaalsContact O-CG 3.24Å; T382-M386 WeakPolarHBondContact O-CG 3.28Å; T382-M386 PolarHBondContact O-N 3.43Å
383E95.3Very high96.8Very high11 Ų116.9 Ų6.95%0.0515%0.049CC..Hα-helixtrans-57.6-53.2177.9-72.1169.3179.400111.2K35 V277 Q360 L364 G379 S380 A385 M386 M387K35-E383 IonicContact NZ-OE1 3.48Å; K35-E383 PolarHBondContact NZ-OE1 3.26Å; V277-E383 HydrophobicContact CB-CG 4.43Å; V277-E383 HydrophobicContact CG1-CG 3.98Å; V277-E383 HydrophobicContact CG2-CG 3.8Å; Q360-E383 PolarHBondContact NE2-OE2 3.32Å; L364-E383 HydrophobicContact CD1-CB 3.77Å; G379-E383 VanDerWaalsContact O-CG 3.31Å; G379-E383 WeakPolarHBondContact O-CG 3.26Å; G379-E383 PolarHBondContact O-N 2.83Å; S380-E383 PolarHBondContact O-N 3.27Å; E383-A385 PolarHBondContact O-N 3.31Å; E383-M386 PolarHBondContact O-N 3.25Å; E383-M387 WeakPolarHBondContact O-CB 3.26Å; E383-M387 VanDerWaalsContact O-CG 3.25Å; E383-M387 WeakPolarHBondContact O-CG 2.98Å; E383-M387 PolarHBondContact O-N 2.87Å
384L96.5Very high96.7Very high1 Ų16.8 Ų6.81%0.0055%0.048CC..Hα-helixtrans-67.4-36.3-1787582.6000112.3L364 F372 T374 S380 M387 G388 T389 A391 M393 L407L364-L384 HydrophobicContact CD1-CB 4.2Å; L364-L384 HydrophobicContact CD2-CB 3.93Å; F372-L384 HydrophobicContact CD1-CB 4.09Å; F372-L384 HydrophobicContact CD1-CD2 3.67Å; F372-L384 HydrophobicContact CE1-CD2 4.24Å; T374-L384 HydrophobicContact CG2-CD2 4.23Å; S380-L384 WeakPolarHBondContact O-CB 3.3Å; S380-L384 WeakPolarHBondContact O-CD2 3.48Å; S380-L384 VanDerWaalsContact O-CG 3.26Å; S380-L384 WeakPolarHBondContact O-CG 3.37Å; S380-L384 PolarHBondContact O-N 3.47Å; L384-M387 PolarHBondContact O-N 3.43Å; L384-G388 PolarHBondContact O-N 3.08Å; L384-T389 PolarHBondContact O-N 2.63Å; L384-T389 VanDerWaalsContact O-N 3.13Å; L384-A391 HydrophobicContact CD1-CB 4.28Å; L384-A391 HydrophobicContact CD2-CB 4.07Å; L384-M393 HydrophobicContact CD2-SD 4.41Å; L384-L407 HydrophobicContact CD1-CD1 4.03Å; L384-L407 HydrophobicContact CD1-CD2 3.36Å; L384-L407 HydrophobicContact CD1-CG 4.32Å; L384-L407 HydrophobicContact CD2-CD2 4.16Å; L384-L407 HydrophobicContact CG-CD2 4.29Å
385A97.3Very high96.7Very high2 Ų27.5 Ų7.52%0.0175%0.053CC..Hα-helixtrans-66.9-39.2178.500000111.5L259 V381 T382 E383 L407 L447 A448 L451L259-A385 HydrophobicContact CD1-CB 4.17Å; L259-A385 HydrophobicContact CD2-CB 4.12Å; V381-A385 WeakPolarHBondContact O-CB 3.46Å; V381-A385 PolarHBondContact O-N 2.97Å; T382-A385 PolarHBondContact O-N 2.98Å; E383-A385 PolarHBondContact O-N 3.31Å; A385-L407 HydrophobicContact CB-CD1 4.1Å; A385-L447 HydrophobicContact CB-CD2 3.95Å; A385-A448 VanDerWaalsContact O-CA 3.24Å; A385-A448 WeakPolarHBondContact O-CA 3.44Å; A385-A448 WeakPolarHBondContact O-CB 3.01Å; A385-A448 PolarHBondContact O-N 3.49Å; A385-L451 HydrophobicContact CB-CD1 3.66Å
386M95.1Very high96.6Very high14 Ų146.7 Ų6.77%0.0695%0.049CC..Hα-helixtrans-74.8-25.6176.2-65.7-173.993.800112.9V277 T279 T382 E383 A448 L451V277-M386 HydrophobicContact CB-SD 4.15Å; V277-M386 HydrophobicContact CG1-SD 3.86Å; T279-M386 HydrophobicContact CG2-CE 3.28Å; T279-M386 HydrophobicContact CG2-SD 3.72Å; T382-M386 HydrophobicContact CG2-CG 4.38Å; T382-M386 HydrophobicContact CG2-SD 3.96Å; T382-M386 WeakPolarHBondContact O-CB 3.34Å; T382-M386 VanDerWaalsContact O-CG 3.24Å; T382-M386 WeakPolarHBondContact O-CG 3.28Å; T382-M386 PolarHBondContact O-N 3.43Å; E383-M386 PolarHBondContact O-N 3.25Å; M386-A448 WeakPolarHBondContact O-CB 3.04Å; M386-L451 HydrophobicContact CG-CB 4.18Å; M386-L451 HydrophobicContact CG-CD1 4.16Å
387M95.4Very high96.3Very high10 Ų108.1 Ų8.15%0.0496%0.055CC..Hα-helixtrans-84.2-26.7176.6-66.7-55.6137.600113.4K278 K281 L284 L364 A365 E383 L384K278-M387 WeakPolarHBondContact O-CE 3.39Å; K281-M387 HydrophobicContact CD-SD 4.32Å; K281-M387 VanDerWaalsContact CE-SD 3.6Å; K281-M387 HydrophobicContact CG-SD 3.95Å; K281-M387 PolarHBondContact NZ-O 2.59Å; L284-M387 HydrophobicContact CD1-CE 3.97Å; L284-M387 HydrophobicContact CD1-SD 4.26Å; L364-M387 HydrophobicContact CB-CB 4.1Å; L364-M387 HydrophobicContact CB-CG 3.91Å; L364-M387 WeakPolarHBondContact O-CB 3.37Å; A365-M387 HydrophobicContact CB-CG 4.48Å; A365-M387 HydrophobicContact CB-SD 3.73Å; E383-M387 WeakPolarHBondContact O-CB 3.26Å; E383-M387 VanDerWaalsContact O-CG 3.25Å; E383-M387 WeakPolarHBondContact O-CG 2.98Å; E383-M387 PolarHBondContact O-N 2.87Å; L384-M387 PolarHBondContact O-N 3.43Å
388G96.7Very high96.1Very high6 Ų69.7 Ų9.76%0.0627%0.067CC..THydrogen-bonded Turntrans89.233.4178.900000113.3L384 S444L384-G388 PolarHBondContact O-N 3.08Å; G388-S444 VanDerWaalsContact C-CB 3.48Å; G388-S444 WeakPolarHBondContact CA-O 3.39Å; G388-S444 WeakPolarHBondContact O-CB 3.47Å
389T97.9Very high96Very high7 Ų710.6 Ų10.64%0.0437%0.072CC..  trans-94.2130.1-177.9-43.50000110.8L364 L369 F372 L384 S444L364-T389 HydrophobicContact CD2-CG2 4.06Å; L364-T389 PolarHBondContact O-OG1 3.1Å; L369-T389 HydrophobicContact CD2-CG2 3.77Å; L369-T389 HydrophobicContact CG-CG2 4.18Å; F372-T389 HydrophobicContact CB-CG2 4.24Å; L384-T389 PolarHBondContact O-N 2.63Å; L384-T389 VanDerWaalsContact O-N 3.13Å; T389-S444 PolarHBondContact O-OG 3Å
390P98.7Very high96.1Very high3 Ų39.4 Ų9.42%0.0196%0.058CC..  trans-59.7151.1167.4-26.537.1000112.8S370 V371 F372 G412 V434 L441S370-P390 WeakPolarHBondContact O-CD 3.4Å; V371-P390 WeakPolarHBondContact CA-O 3.3Å; V371-P390 HydrophobicContact CG2-CB 4.42Å; F372-P390 PolarHBondContact N-O 3.37Å; P390-G412 VanDerWaalsContact CA-O 3.3Å; P390-G412 WeakPolarHBondContact CA-O 3.38Å; P390-V434 HydrophobicContact CB-CG1 3.6Å; P390-L441 HydrophobicContact CG-CB 4.07Å; P390-L441 HydrophobicContact CG-CD1 3.98Å
391A98.8Very high96.1Very high0 Ų09.1 Ų9.10%06%0.057CC..EExtended strand (participates in β ladder)trans-139.4149.6-177.500000115.7F372 L384 M393 L407 G412 A413 V414F372-A391 CarbonylContact O-C 3.48Å; F372-A391 WeakPolarHBondContact O-CA 3.37Å; F372-A391 WeakPolarHBondContact O-CB 3.44Å; L384-A391 HydrophobicContact CD1-CB 4.28Å; L384-A391 HydrophobicContact CD2-CB 4.07Å; A391-M393 HydrophobicContact CB-CG 4.37Å; A391-M393 HydrophobicContact CB-SD 3.63Å; A391-L407 HydrophobicContact CB-CD2 4.17Å; A391-G412 PolarHBondContact N-O 2.86Å; A391-G412 VanDerWaalsContact N-O 3.08Å; A391-A413 HydrophobicContact CB-CB 4.07Å; A391-A413 CarbonylContact O-C 3.58Å; A391-A413 WeakPolarHBondContact O-CA 3.5Å; A391-V414 PolarHBondContact O-N 2.88Å
392V98.8Very high96.1Very high0 Ų09.2 Ų9.20%06%0.057CC..EExtended strand (participates in β ladder)trans-110.9116.1162177.30000107.1V371 F372 V373 T374 I394 I416 T430 L431 V434V371-V392 HydrophobicContact CG1-CG2 4.03Å; F372-V392 PolarHBondContact O-N 2.84Å; V373-V392 VanDerWaalsContact CA-O 3.31Å; V373-V392 WeakPolarHBondContact CA-O 3.43Å; V373-V392 HydrophobicContact CG2-CB 4.26Å; T374-V392 PolarHBondContact N-O 3.13Å; V392-I394 HydrophobicContact CG1-CG1 4.3Å; V392-I416 HydrophobicContact CG1-CD1 3.86Å; V392-I416 HydrophobicContact CG1-CG1 4.16Å; V392-T430 HydrophobicContact CG1-CG2 4.06Å; V392-T430 HydrophobicContact CG2-CG2 3.94Å; V392-L431 HydrophobicContact CG2-CD2 4.19Å; V392-V434 HydrophobicContact CG2-CB 4.47Å; V392-V434 HydrophobicContact CG2-CG2 3.95Å
393M98.6Very high96.1Very high0 Ų09 Ų90%06%0.056CC..EExtended strand (participates in β ladder)trans-103.2128.1-172.9-52.1-61.7-72.200109.5T374 V381 L384 A391 A404 L407 A413 V414 V415 I416T374-M393 HydrophobicContact CG2-CE 3.82Å; T374-M393 HydrophobicContact CG2-SD 3.55Å; T374-M393 VanDerWaalsContact CG2-SD 3.55Å; T374-M393 CarbonylContact O-C 3.6Å; T374-M393 VanDerWaalsContact O-CA 3.31Å; T374-M393 WeakPolarHBondContact O-CA 3.46Å; V381-M393 HydrophobicContact CG2-CE 3.43Å; V381-M393 VanDerWaalsContact CG2-CE 3.43Å; L384-M393 HydrophobicContact CD2-SD 4.41Å; A391-M393 HydrophobicContact CB-CG 4.37Å; A391-M393 HydrophobicContact CB-SD 3.63Å; M393-A404 HydrophobicContact CB-CB 3.65Å; M393-A404 HydrophobicContact CE-CB 4.33Å; M393-A404 HydrophobicContact CG-CB 4.22Å; M393-L407 HydrophobicContact CE-CD2 4.31Å; M393-L407 HydrophobicContact CG-CD2 4.44Å; M393-L407 HydrophobicContact SD-CD2 3.98Å; M393-A413 HydrophobicContact CG-CB 4.1Å; M393-V414 PolarHBondContact N-O 3.41Å; M393-V415 HydrophobicContact CB-CG2 4.17Å; M393-V415 WeakPolarHBondContact O-CA 3.17Å; M393-I416 PolarHBondContact O-N 3.13Å
394I97.8Very high96.3Very high0 Ų08.5 Ų8.50%05%0.054CC..  trans-129.278.9-176-40.6-174.6000109.4F305 V373 T374 H375 V392 I416 K418 L421 M427F305-I394 HydrophobicContact CE1-CB 4.07Å; F305-I394 HydrophobicContact CE1-CD1 4.04Å; F305-I394 HydrophobicContact CE1-CG1 4.39Å; F305-I394 HydrophobicContact CZ-CD1 4.09Å; V373-I394 HydrophobicContact CG1-CD1 3.66Å; V373-I394 HydrophobicContact CG1-CG1 4.26Å; T374-I394 PolarHBondContact O-N 2.56Å; H375-I394 VanDerWaalsContact CA-O 3.25Å; H375-I394 WeakPolarHBondContact CA-O 3.34Å; V392-I394 HydrophobicContact CG1-CG1 4.3Å; I394-I416 HydrophobicContact CB-CG1 4.27Å; I394-I416 HydrophobicContact CD1-CD1 3.69Å; I394-I416 HydrophobicContact CD1-CG1 4.14Å; I394-I416 HydrophobicContact CG1-CD1 3.76Å; I394-I416 HydrophobicContact CG1-CG1 3.63Å; I394-I416 HydrophobicContact CG2-CG1 4.23Å; I394-K418 HydrophobicContact CG2-CB 4.1Å; I394-L421 HydrophobicContact CD1-CD1 4.36Å; I394-L421 HydrophobicContact CD1-CD2 3.5Å; I394-L421 HydrophobicContact CD1-CG 4.01Å; I394-L421 HydrophobicContact CG2-CD1 3.97Å; I394-L421 HydrophobicContact CG2-CG 4.13Å; I394-M427 HydrophobicContact CD1-CE 4.25Å
395P96.7Very high96.3Very high15 Ų1510.1 Ų10.110%0.0976%0.061CC..  trans-56.1141.3-178.1-25.536.3000113H375 Q400 A404 V415H375-P395 WeakPolarHBondContact O-CA 3.4Å; P395-Q400 HydrophobicContact CB-CB 4.1Å; P395-A404 HydrophobicContact CG-CB 3.73Å; P395-V415 HydrophobicContact CG-CG1 4.08Å
396L94.7Very high96.4Very high2 Ų210 Ų101%0.016%0.06CC..  trans-119-39.6178.7-57.7176.9000112.9W98 T102 F305 A309 H375 K418W98-L396 HydrophobicContact CD2-CD1 4.15Å; W98-L396 HydrophobicContact CD2-CD2 4.38Å; W98-L396 HydrophobicContact CE3-CD1 4.08Å; W98-L396 HydrophobicContact CE3-CD2 3.66Å; W98-L396 HydrophobicContact CH2-CD1 3.79Å; W98-L396 HydrophobicContact CH2-CD2 4.38Å; W98-L396 HydrophobicContact CZ2-CD1 3.85Å; W98-L396 HydrophobicContact CZ3-CD1 3.89Å; W98-L396 HydrophobicContact CZ3-CD2 3.66Å; W98-L396 HydrophobicContact CZ3-CG 4.42Å; T102-L396 PolarHBondContact OG1-O 2.85Å; F305-L396 HydrophobicContact CD1-CD1 4.24Å; A309-L396 HydrophobicContact CB-CD1 3.44Å; A309-L396 VanDerWaalsContact CB-CD1 3.44Å; H375-L396 HydrophobicContact CB-CD1 4.16Å; H375-L396 HydrophobicContact CB-CG 4.22Å; L396-K418 HydrophobicContact CD2-CB 3.93Å; L396-K418 HydrophobicContact CD2-CD 4.1Å
397F92Very high96.5Very high29 Ų299.5 Ų9.513%0.1276%0.058CC..SBendtrans-166.7177.6-177.757.5-90.7000113.1L94 A97 T102 N308 A309 D399 Q400L94-F397 HydrophobicContact CD2-CD2 4.29Å; L94-F397 HydrophobicContact CD2-CE1 4.1Å; L94-F397 HydrophobicContact CD2-CE2 3.65Å; L94-F397 HydrophobicContact CD2-CZ 3.55Å; A97-F397 HydrophobicContact CB-CB 4.48Å; A97-F397 HydrophobicContact CB-CD1 3.57Å; A97-F397 HydrophobicContact CB-CE1 4.16Å; A97-F397 HydrophobicContact CB-CG 4.34Å; T102-F397 HydrophobicContact CG2-CB 4.04Å; N308-F397 HydrophobicContact CB-CZ 4.21Å; A309-F397 HydrophobicContact CB-CE1 4.19Å; F397-D399 PolarHBondContact O-N 2.93Å; F397-Q400 VanDerWaalsContact CE2-NE2 3.34Å; F397-Q400 VanDerWaalsContact CZ-NE2 3.31Å; F397-Q400 VanDerWaalsContact N-OE1 3.12Å; F397-Q400 WeakPolarHBondContact O-CB 3.48Å; F397-Q400 WeakPolarHBondContact O-CG 3.42Å; F397-Q400 PolarHBondContact O-N 3.23Å; F397-Q400 PolarHBondContact O-NE2 2.78Å; F397-Q400 PolarHBondContact O-OE1 3.38Å
398A90.8Very high96.6Very high45 Ų4513.4 Ų13.437%0.3727%0.074SC..THydrogen-bonded Turntrans53.4-130.5175.400000113.2Q194 Q400Q194-A398 WeakPolarHBondContact CA-O 3.3Å; A398-Q400 VanDerWaalsContact C-N 3.3Å; A398-Q400 PolarHBondContact O-N 2.88Å
399D93.4Very high96.7Very high31 Ų3117.5 Ų17.517%0.1669%0.088CC..THydrogen-bonded Turntrans-87.64.2-175.168.1-30000113.9T193 F397 G401 R402 N403T193-D399 HydrophobicContact CG2-CB 4.26Å; T193-D399 VanDerWaalsContact O-CA 3.28Å; T193-D399 WeakPolarHBondContact O-CA 3.15Å; T193-D399 WeakPolarHBondContact O-CB 3.48Å; F397-D399 PolarHBondContact O-N 2.93Å; D399-G401 PolarHBondContact O-N 3.06Å; D399-R402 PolarHBondContact O-N 2.87Å; D399-N403 WeakPolarHBondContact O-CB 3.4Å; D399-N403 PolarHBondContact O-N 2.89Å; D399-N403 PolarHBondContact O-ND2 3.04Å; D399-N403 PolarHBondContact OD2-ND2 3.37Å
400Q95.9Very high96.7Very high6 Ų619.1 Ų19.13%0.02810%0.095CC..Hα-helixtrans-64.6-38.3-171.9-61.8169.715.600112.5H375 P395 F397 A398 N403 A404H375-Q400 PolarHBondContact CD2-NE2 3.05Å; H375-Q400 VanDerWaalsContact CD2-NE2 3.33Å; H375-Q400 WeakPolarHBondContact O-CB 3.33Å; P395-Q400 HydrophobicContact CB-CB 4.1Å; F397-Q400 VanDerWaalsContact CE2-NE2 3.34Å; F397-Q400 VanDerWaalsContact CZ-NE2 3.31Å; F397-Q400 VanDerWaalsContact N-OE1 3.12Å; F397-Q400 WeakPolarHBondContact O-CB 3.48Å; F397-Q400 WeakPolarHBondContact O-CG 3.42Å; F397-Q400 PolarHBondContact O-N 3.23Å; F397-Q400 PolarHBondContact O-NE2 2.78Å; F397-Q400 PolarHBondContact O-OE1 3.38Å; A398-Q400 VanDerWaalsContact C-N 3.3Å; A398-Q400 PolarHBondContact O-N 2.88Å; Q400-N403 PolarHBondContact O-N 3.28Å; Q400-A404 VanDerWaalsContact O-CB 3.22Å; Q400-A404 WeakPolarHBondContact O-CB 3.46Å; Q400-A404 PolarHBondContact O-N 3.18Å
401G95.4Very high96.6Very high5 Ų519.8 Ų19.85%0.05210%0.103CC..Hα-helixtrans-59.9-50.1175.200000111.5S195 D399 N403 A404 Q405S195-G401 CarbonylContact O-C 3.57Å; D399-G401 PolarHBondContact O-N 3.06Å; G401-N403 PolarHBondContact O-N 2.67Å; G401-A404 WeakPolarHBondContact O-CB 3.22Å; G401-A404 PolarHBondContact O-N 2.87Å; G401-Q405 WeakPolarHBondContact O-CG 3.19Å; G401-Q405 PolarHBondContact O-N 3.47Å
402R95.7Very high96.6Very high3 Ų320 Ų201%0.01110%0.104CC..Hα-helixtrans-59.5-47.5177.6-177.5-165.4176.9-71.23.2110.8N172 P191 G192 S195 D260 F261 D399 A404 Q405 M406N172-R402 PolarHBondContact ND2-NH1 2.97Å; N172-R402 VanDerWaalsContact ND2-NH1 3.16Å; P191-R402 HydrophobicContact CB-CG 4.29Å; G192-R402 WeakPolarHBondContact O-CD 3.48Å; S195-R402 VanDerWaalsContact O-CA 3.3Å; S195-R402 WeakPolarHBondContact O-CA 3.34Å; S195-R402 WeakPolarHBondContact O-CB 3.26Å; S195-R402 PolarHBondContact O-N 2.95Å; D260-R402 VanDerWaalsContact CG-NH2 3.3Å; D260-R402 IonicContact OD1-CZ 2.95Å; D260-R402 VanDerWaalsContact OD1-CZ 3.28Å; D260-R402 IonicContact OD1-NH1 3.4Å; D260-R402 PolarHBondContact OD1-NH1 3.37Å; D260-R402 IonicContact OD1-NH2 3.96Å; D260-R402 PolarHBondContact OD1-NH2 3.4Å; D260-R402 IonicContact OD2-CZ 2.73Å; D260-R402 IonicContact OD2-NH1 3.57Å; D260-R402 IonicContact OD2-NH2 3.76Å; D260-R402 PolarHBondContact OD2-NH2 3.35Å; F261-R402 HydrophobicContact CE2-CG 4.2Å; D399-R402 PolarHBondContact O-N 2.87Å; R402-A404 VanDerWaalsContact C-N 3.32Å; R402-A404 PolarHBondContact O-N 3.3Å; R402-Q405 PolarHBondContact O-N 2.97Å; R402-M406 VanDerWaalsContact O-CB 3.27Å; R402-M406 WeakPolarHBondContact O-CB 3.44Å; R402-M406 PolarHBondContact O-N 2.79Å
403N97.6Very high96.6Very high0 Ų020.1 Ų20.10%011%0.106CC..Hα-helixtrans-64.2-36.8-179.8-67.3-24000112.2N172 G376 L378 V381 D399 Q400 G401 M406 L407N172-N403 PolarHBondContact ND2-OD1 3.21Å; G376-N403 WeakPolarHBondContact O-CB 3.47Å; G376-N403 PolarHBondContact O-ND2 3.14Å; L378-N403 PolarHBondContact N-ND2 3.39Å; V381-N403 HydrophobicContact CG2-CB 4.23Å; D399-N403 WeakPolarHBondContact O-CB 3.4Å; D399-N403 PolarHBondContact O-N 2.89Å; D399-N403 PolarHBondContact O-ND2 3.04Å; D399-N403 PolarHBondContact OD2-ND2 3.37Å; Q400-N403 PolarHBondContact O-N 3.28Å; G401-N403 PolarHBondContact O-N 2.67Å; N403-M406 WeakPolarHBondContact O-CB 3.47Å; N403-M406 PolarHBondContact O-N 2.76Å; N403-L407 PolarHBondContact O-N 2.78Å; N403-L407 VanDerWaalsContact O-N 3.09Å
404A98.2Very high96.6Very high0 Ų021.3 Ų21.30%011%0.113CC..Hα-helixtrans-65.9-45.8175.800000111.6M393 P395 Q400 G401 R402 M406 L407 K408 V415M393-A404 HydrophobicContact CB-CB 3.65Å; M393-A404 HydrophobicContact CE-CB 4.33Å; M393-A404 HydrophobicContact CG-CB 4.22Å; P395-A404 HydrophobicContact CG-CB 3.73Å; Q400-A404 VanDerWaalsContact O-CB 3.22Å; Q400-A404 WeakPolarHBondContact O-CB 3.46Å; Q400-A404 PolarHBondContact O-N 3.18Å; G401-A404 WeakPolarHBondContact O-CB 3.22Å; G401-A404 PolarHBondContact O-N 2.87Å; R402-A404 VanDerWaalsContact C-N 3.32Å; R402-A404 PolarHBondContact O-N 3.3Å; A404-M406 VanDerWaalsContact C-N 3.33Å; A404-M406 PolarHBondContact O-N 2.88Å; A404-L407 PolarHBondContact O-N 2.97Å; A404-K408 WeakPolarHBondContact O-CB 3.04Å; A404-K408 PolarHBondContact O-N 2.8Å; A404-V415 HydrophobicContact CB-CG1 3.97Å; A404-V415 HydrophobicContact CB-CG2 3.77Å; A404-V415 WeakPolarHBondContact O-CG2 3.43Å
405Q97.6Very high96.6Very high35 Ų3522.6 Ų22.616%0.16412%0.121CC..Hα-helixtrans-66.6-36175.5-62.6-66.1-11.900112.3E196 F261 G401 R402 L407 K408 R409E196-Q405 VanDerWaalsContact O-CG 3.23Å; E196-Q405 WeakPolarHBondContact O-CG 3.39Å; E196-Q405 PolarHBondContact O-NE2 3.16Å; F261-Q405 HydrophobicContact CZ-CB 3.94Å; G401-Q405 WeakPolarHBondContact O-CG 3.19Å; G401-Q405 PolarHBondContact O-N 3.47Å; R402-Q405 PolarHBondContact O-N 2.97Å; Q405-L407 VanDerWaalsContact C-N 3.3Å; Q405-L407 PolarHBondContact O-N 2.8Å; Q405-K408 PolarHBondContact O-N 2.88Å; Q405-R409 PolarHBondContact O-N 3.39Å
406M97.8Very high96.6Very high0 Ų022.2 Ų22.20%012%0.118CC..Hα-helixtrans-57.5-43.1173.8178.5-169.670.400111.1L259 D260 F261 L378 V381 R402 N403 A404 R409 H410L259-M406 HydrophobicContact CD1-CE 4.36Å; L259-M406 HydrophobicContact CD2-CE 3.95Å; L259-M406 HydrophobicContact CG-CE 3.81Å; L259-M406 HydrophobicContact CG-CG 4.46Å; L259-M406 HydrophobicContact CG-SD 4.12Å; L259-M406 WeakPolarHBondContact O-CG 3.44Å; D260-M406 HydrophobicContact CB-SD 3.95Å; F261-M406 HydrophobicContact CD2-CB 4.26Å; F261-M406 HydrophobicContact CE2-CB 3.66Å; F261-M406 HydrophobicContact CE2-CG 4.38Å; F261-M406 VanDerWaalsContact CZ-CA 3.45Å; F261-M406 HydrophobicContact CZ-CB 4.02Å; F261-M406 VanDerWaalsContact CZ-N 3.33Å; L378-M406 HydrophobicContact CD1-CE 4.16Å; V381-M406 HydrophobicContact CG1-CE 3.43Å; V381-M406 VanDerWaalsContact CG1-CE 3.43Å; R402-M406 VanDerWaalsContact O-CB 3.27Å; R402-M406 WeakPolarHBondContact O-CB 3.44Å; R402-M406 PolarHBondContact O-N 2.79Å; N403-M406 WeakPolarHBondContact O-CB 3.47Å; N403-M406 PolarHBondContact O-N 2.76Å; A404-M406 VanDerWaalsContact C-N 3.33Å; A404-M406 PolarHBondContact O-N 2.88Å; M406-R409 WeakPolarHBondContact O-CD 3.44Å; M406-R409 WeakPolarHBondContact O-CG 3.31Å; M406-H410 PolarHBondContact O-CD2 3.48Å; M406-H410 VanDerWaalsContact O-CD2 3.29Å
407L98.2Very high96.6Very high2 Ų228.6 Ų28.61%0.0115%0.147CC..Hα-helixtrans-75.7-43177.1-176.166.5000112.3L259 V381 L384 A385 A391 M393 N403 A404 Q405 R409 H410 A413 L447L259-L407 HydrophobicContact CD1-CD1 4.23Å; V381-L407 HydrophobicContact CG1-CB 4.16Å; V381-L407 HydrophobicContact CG1-CD2 4.49Å; L384-L407 HydrophobicContact CD1-CD1 4.03Å; L384-L407 HydrophobicContact CD1-CD2 3.36Å; L384-L407 HydrophobicContact CD1-CG 4.32Å; L384-L407 HydrophobicContact CD2-CD2 4.16Å; L384-L407 HydrophobicContact CG-CD2 4.29Å; A385-L407 HydrophobicContact CB-CD1 4.1Å; A391-L407 HydrophobicContact CB-CD2 4.17Å; M393-L407 HydrophobicContact CE-CD2 4.31Å; M393-L407 HydrophobicContact CG-CD2 4.44Å; M393-L407 HydrophobicContact SD-CD2 3.98Å; N403-L407 PolarHBondContact O-N 2.78Å; N403-L407 VanDerWaalsContact O-N 3.09Å; A404-L407 PolarHBondContact O-N 2.97Å; Q405-L407 VanDerWaalsContact C-N 3.3Å; Q405-L407 PolarHBondContact O-N 2.8Å; L407-R409 PolarHBondContact O-N 3.3Å; L407-R409 VanDerWaalsContact O-N 3.13Å; L407-H410 WeakPolarHBondContact O-CB 3.49Å; L407-H410 PolarHBondContact O-N 2.97Å; L407-A413 HydrophobicContact CB-CB 4.48Å; L407-A413 HydrophobicContact CD2-CB 3.66Å; L407-A413 HydrophobicContact CG-CB 3.8Å; L407-L447 HydrophobicContact CD1-CD2 3.96Å
408K98.2Very high96.8Very high92 Ų9228.5 Ų28.540%0.415%0.147SC..Hα-helixtrans-51.7-38.5-178.2-179.9-176.8173.5-179.90113A404 Q405 H410 G411 V415A404-K408 WeakPolarHBondContact O-CB 3.04Å; A404-K408 PolarHBondContact O-N 2.8Å; Q405-K408 PolarHBondContact O-N 2.88Å; K408-H410 PolarHBondContact O-N 3.47Å; K408-H410 VanDerWaalsContact O-N 3.13Å; K408-G411 PolarHBondContact O-N 2.94Å; K408-V415 HydrophobicContact CB-CG2 3.81Å; K408-V415 HydrophobicContact CD-CB 4.24Å; K408-V415 HydrophobicContact CD-CG2 3.75Å; K408-V415 HydrophobicContact CG-CG2 4.22Å
409R97.3Very high97Very high92 Ų9231.1 Ų31.135%0.34716%0.155SC..THydrogen-bonded Turntrans-59.8-25.8-178.278.6-173.1-69.481.73114.5D199 Q405 M406 L407 G411D199-R409 IonicContact OD1-CZ 3.44Å; D199-R409 IonicContact OD1-NH1 3.13Å; D199-R409 PolarHBondContact OD1-NH1 3.23Å; D199-R409 IonicContact OD1-NH2 3.07Å; D199-R409 IonicContact OD2-CZ 3.72Å; D199-R409 IonicContact OD2-NH1 3.37Å; D199-R409 PolarHBondContact OD2-NH1 2.96Å; D199-R409 IonicContact OD2-NH2 2.9Å; D199-R409 PolarHBondContact OD2-NH2 3.29Å; Q405-R409 PolarHBondContact O-N 3.39Å; M406-R409 WeakPolarHBondContact O-CD 3.44Å; M406-R409 WeakPolarHBondContact O-CG 3.31Å; L407-R409 PolarHBondContact O-N 3.3Å; L407-R409 VanDerWaalsContact O-N 3.13Å; R409-G411 PolarHBondContact O-N 3.27Å
410H98.1Very high97.1Very high41 Ų4132 Ų3219%0.1916%0.159CC..THydrogen-bonded Turntrans-78-9178-65.1-77.1000111.8L258 L259 M406 L407 K408 G412 N443 L447L258-H410 PolarHBondContact O-CE1 3.3Å; L259-H410 PolarHBondContact O-NE2 3.42Å; M406-H410 PolarHBondContact O-CD2 3.48Å; M406-H410 VanDerWaalsContact O-CD2 3.29Å; L407-H410 WeakPolarHBondContact O-CB 3.49Å; L407-H410 PolarHBondContact O-N 2.97Å; K408-H410 PolarHBondContact O-N 3.47Å; K408-H410 VanDerWaalsContact O-N 3.13Å; H410-G412 VanDerWaalsContact C-N 3.33Å; H410-N443 VanDerWaalsContact O-CB 3.26Å; H410-N443 WeakPolarHBondContact O-CB 3.36Å; H410-L447 HydrophobicContact CB-CD2 3.92Å
411G97.9Very high97.2Very high18 Ų1831.7 Ų31.719%0.18616%0.158CC..THydrogen-bonded Turntrans81.39.5175.300000114.6K408 R409 Y440 N443K408-G411 PolarHBondContact O-N 2.94Å; R409-G411 PolarHBondContact O-N 3.27Å; G411-Y440 WeakPolarHBondContact O-CD1 3.46Å; G411-N443 PolarHBondContact O-ND2 2.96Å; G411-N443 VanDerWaalsContact O-ND2 3.09Å
412G97.7Very high97.2Very high3 Ų332.7 Ų32.73%0.03117%0.166CC..SBendtrans-97.8-1.8176.700000114.6P390 A391 H410 S444P390-G412 VanDerWaalsContact CA-O 3.3Å; P390-G412 WeakPolarHBondContact CA-O 3.38Å; A391-G412 PolarHBondContact N-O 2.86Å; A391-G412 VanDerWaalsContact N-O 3.08Å; H410-G412 VanDerWaalsContact C-N 3.33Å; G412-S444 VanDerWaalsContact CA-OG 3.31Å; G412-S444 WeakPolarHBondContact CA-OG 3.3Å; G412-S444 PolarHBondContact O-OG 3.14Å
413A98.6Very high97.3Very high4 Ų436 Ų363%0.03318%0.184CC..EExtended strand (participates in β ladder)trans-141.5153-177.700000113.6A391 M393 L407A391-A413 HydrophobicContact CB-CB 4.07Å; A391-A413 CarbonylContact O-C 3.58Å; A391-A413 WeakPolarHBondContact O-CA 3.5Å; M393-A413 HydrophobicContact CG-CB 4.1Å; L407-A413 HydrophobicContact CB-CB 4.48Å; L407-A413 HydrophobicContact CD2-CB 3.66Å; L407-A413 HydrophobicContact CG-CB 3.8Å
414V98.5Very high97.4Very high24 Ų2438.1 Ų38.115%0.14520%0.197CC..EExtended strand (participates in β ladder)trans-108.1143.6166.6-179.50000108.4A391 M393 I416 T430 V434 Y440A391-V414 PolarHBondContact O-N 2.88Å; M393-V414 PolarHBondContact N-O 3.41Å; V414-I416 HydrophobicContact CG1-CG2 3.94Å; V414-T430 HydrophobicContact CB-CG2 4.38Å; V414-T430 HydrophobicContact CG1-CG2 4.07Å; V414-V434 HydrophobicContact CB-CG2 4.32Å; V414-V434 HydrophobicContact CG2-CG2 3.62Å; V414-Y440 HydrophobicContact CG2-CE1 3.51Å; V414-Y440 VanDerWaalsContact CG2-OH 3.32Å; V414-Y440 WeakPolarHBondContact CG2-OH 3.48Å
415V98.2Very high97.4Very high27 Ų2743.8 Ų43.816%0.16422%0.223CC..EExtended strand (participates in β ladder)trans-113.1129.6173.4-175.60000107.2M393 P395 A404 K408M393-V415 HydrophobicContact CB-CG2 4.17Å; M393-V415 WeakPolarHBondContact O-CA 3.17Å; P395-V415 HydrophobicContact CG-CG1 4.08Å; A404-V415 HydrophobicContact CB-CG1 3.97Å; A404-V415 HydrophobicContact CB-CG2 3.77Å; A404-V415 WeakPolarHBondContact O-CG2 3.43Å; K408-V415 HydrophobicContact CB-CG2 3.81Å; K408-V415 HydrophobicContact CD-CB 4.24Å; K408-V415 HydrophobicContact CD-CG2 3.75Å; K408-V415 HydrophobicContact CG-CG2 4.22Å
416I97.1Very high97.4Very high7 Ų745.2 Ų45.24%0.03623%0.229CC..  trans-125.4149.3178.464.5172.3000110V392 M393 I394 V414 F426 M427 T430V392-I416 HydrophobicContact CG1-CD1 3.86Å; V392-I416 HydrophobicContact CG1-CG1 4.16Å; M393-I416 PolarHBondContact O-N 3.13Å; I394-I416 HydrophobicContact CB-CG1 4.27Å; I394-I416 HydrophobicContact CD1-CD1 3.69Å; I394-I416 HydrophobicContact CD1-CG1 4.14Å; I394-I416 HydrophobicContact CG1-CD1 3.76Å; I394-I416 HydrophobicContact CG1-CG1 3.63Å; I394-I416 HydrophobicContact CG2-CG1 4.23Å; V414-I416 HydrophobicContact CG1-CG2 3.94Å; I416-F426 HydrophobicContact CB-CE1 3.94Å; I416-F426 HydrophobicContact CB-CZ 4.4Å; I416-F426 HydrophobicContact CD1-CE1 4.38Å; I416-F426 HydrophobicContact CG2-CE1 3.62Å; I416-F426 HydrophobicContact CG2-CZ 3.81Å; I416-M427 HydrophobicContact CD1-CE 3.91Å; I416-M427 HydrophobicContact CD1-SD 3.28Å; I416-M427 WeakPolarHBondContact CD1-SD 3.33Å; I416-T430 HydrophobicContact CG2-CG2 4.13Å
417E95.1Very high97.5Very high136 Ų13645.2 Ų45.264%0.63623%0.229SC*.  trans-72.5141.9175.1-64.3176.3-16300109.5N419 N420E417-N419 PolarHBondContact O-N 2.9Å; E417-N419 VanDerWaalsContact O-N 3.15Å; E417-N420 WeakPolarHBondContact O-CB 3.28Å; E417-N420 PolarHBondContact O-N 3.17Å
418K95.3Very high97.5Very high28 Ų2848 Ų4812%0.12224%0.241CC..G310 helixtrans-57.7-33.8-175.171.8-175.1-179.8-170.50113.7A97 E100 I394 L396 N420 L421A97-K418 PolarHBondContact O-NZ 3.45Å; E100-K418 PolarHBondContact O-NZ 2.95Å; I394-K418 HydrophobicContact CG2-CB 4.1Å; L396-K418 HydrophobicContact CD2-CB 3.93Å; L396-K418 HydrophobicContact CD2-CD 4.1Å; K418-N420 PolarHBondContact O-N 3.45Å; K418-L421 WeakPolarHBondContact O-CB 3.43Å; K418-L421 WeakPolarHBondContact O-CG 3.46Å; K418-L421 PolarHBondContact O-N 3.3Å
419N94.8Very high97.5Very high99 Ų9948.5 Ų48.553%0.52925%0.245SC..G310 helixtrans-67.2-21.3179.1-66.5-24.4000112.3E417 L421 A422E417-N419 PolarHBondContact O-N 2.9Å; E417-N419 VanDerWaalsContact O-N 3.15Å; N419-L421 PolarHBondContact O-N 3.24Å; N419-A422 WeakPolarHBondContact O-CB 3.24Å; N419-A422 PolarHBondContact O-N 3.15Å
420N96.7Very high97.6Very high49 Ų4944.6 Ų44.626%0.26223%0.231SC..G310 helixtrans-71.6-8.8172.8-57.4140.9000112.9E417 K418 A422 D423 F426 M427E417-N420 WeakPolarHBondContact O-CB 3.28Å; E417-N420 PolarHBondContact O-N 3.17Å; K418-N420 PolarHBondContact O-N 3.45Å; N420-A422 PolarHBondContact O-N 3.09Å; N420-D423 PolarHBondContact O-N 2.85Å; N420-F426 HydrophobicContact CB-CD1 3.63Å; N420-F426 HydrophobicContact CB-CE1 3.62Å; N420-M427 WeakPolarHBondContact O-CG 3.49Å
421L96.7Very high97.6Very high0 Ų042.8 Ų42.80%022%0.223CC..G310 helixtrans-59-27.7167.6-80.8170.6000112.4W98 M314 F318 S321 L322 I394 K418 N419 D423 M427W98-L421 HydrophobicContact CZ3-CD1 3.76Å; M314-L421 HydrophobicContact CE-CD1 4.42Å; F318-L421 HydrophobicContact CB-CB 3.97Å; F318-L421 HydrophobicContact CD1-CB 3.91Å; F318-L421 HydrophobicContact CD2-CB 3.92Å; F318-L421 HydrophobicContact CD2-CD1 3.83Å; F318-L421 HydrophobicContact CE1-CB 4.4Å; F318-L421 HydrophobicContact CE2-CB 4.42Å; F318-L421 HydrophobicContact CE2-CD1 4.31Å; F318-L421 HydrophobicContact CG-CB 3.66Å; F318-L421 HydrophobicContact CG-CD1 4.34Å; S321-L421 WeakPolarHBondContact CB-O 3.28Å; S321-L421 PolarHBondContact OG-O 3.18Å; L322-L421 HydrophobicContact CD2-CD2 4.27Å; I394-L421 HydrophobicContact CD1-CD1 4.36Å; I394-L421 HydrophobicContact CD1-CD2 3.5Å; I394-L421 HydrophobicContact CD1-CG 4.01Å; I394-L421 HydrophobicContact CG2-CD1 3.97Å; I394-L421 HydrophobicContact CG2-CG 4.13Å; K418-L421 WeakPolarHBondContact O-CB 3.43Å; K418-L421 WeakPolarHBondContact O-CG 3.46Å; K418-L421 PolarHBondContact O-N 3.3Å; N419-L421 PolarHBondContact O-N 3.24Å; L421-D423 VanDerWaalsContact C-N 3.26Å; L421-D423 PolarHBondContact O-N 2.79Å; L421-M427 HydrophobicContact CD2-CE 3.94Å; L421-M427 HydrophobicContact CD2-SD 4.03Å
422A97Very high97.6Very high26 Ų2644.5 Ų44.522%0.21523%0.226CC..G310 helixtrans-72.1-18.2174.700000113.6E317 F318 N419 N420 T424E317-A422 HydrophobicContact CG-CB 3.64Å; E317-A422 VanDerWaalsContact OE1-CB 3.3Å; E317-A422 WeakPolarHBondContact OE1-CB 3.22Å; F318-A422 HydrophobicContact CD1-CB 3.85Å; F318-A422 HydrophobicContact CE1-CB 3.9Å; N419-A422 WeakPolarHBondContact O-CB 3.24Å; N419-A422 PolarHBondContact O-N 3.15Å; N420-A422 PolarHBondContact O-N 3.09Å; A422-T424 PolarHBondContact O-N 2.86Å
423D98Very high97.7Very high73 Ų7349.8 Ų49.839%0.3925%0.248SC..  trans-92.594.3-177.9-174.1-22.7000110.6N420 L421 H425 F426 M427N420-D423 PolarHBondContact O-N 2.85Å; L421-D423 VanDerWaalsContact C-N 3.26Å; L421-D423 PolarHBondContact O-N 2.79Å; D423-H425 PolarHBondContact O-N 3.29Å; D423-H425 PolarHBondContact OD1-N 3.35Å; D423-H425 VanDerWaalsContact OD1-N 3.07Å; D423-F426 HydrophobicContact CB-CB 3.84Å; D423-F426 PolarHBondContact O-N 3.32Å; D423-F426 PolarHBondContact OD1-N 3Å; D423-M427 WeakPolarHBondContact O-CB 3.19Å; D423-M427 WeakPolarHBondContact O-CG 3.14Å; D423-M427 PolarHBondContact O-N 3.37Å
424T98.3Very high97.7Very high44 Ų4449.8 Ų49.827%0.2725%0.248SC..Hα-helixtrans-52-42.3178.9-54.70000112.5S321 D324 V325 A422 K428S321-T424 WeakPolarHBondContact CA-OG1 3.47Å; S321-T424 WeakPolarHBondContact OG-CA 3.48Å; S321-T424 PolarHBondContact OG-N 2.88Å; S321-T424 PolarHBondContact OG-OG1 3.15Å; D324-T424 HydrophobicContact CB-CG2 3.51Å; V325-T424 HydrophobicContact CG2-CG2 3.97Å; V325-T424 WeakPolarHBondContact CG2-O 3.38Å; A422-T424 PolarHBondContact O-N 2.86Å; T424-K428 WeakPolarHBondContact O-CB 3.33Å; T424-K428 PolarHBondContact O-N 3.47Å
425H98.3Very high97.7Very high120 Ų12050.5 Ų50.556%0.55625%0.25SS*.Hα-helixtrans-69.4-49.4-176.2-178.2-89.9000110.3D423 M427 K428 E429D423-H425 PolarHBondContact O-N 3.29Å; D423-H425 PolarHBondContact OD1-N 3.35Å; D423-H425 VanDerWaalsContact OD1-N 3.07Å; H425-M427 VanDerWaalsContact C-N 3.33Å; H425-M427 PolarHBondContact O-N 3.46Å; H425-K428 PolarHBondContact O-N 3.38Å; H425-E429 IonicContact CE1-OE1 3.41Å; H425-E429 PolarHBondContact CE1-OE1 2.97Å; H425-E429 IonicContact CE1-OE2 3.82Å; H425-E429 PolarHBondContact CE1-OE2 3.47Å; H425-E429 VanDerWaalsContact CE1-OE2 3.32Å; H425-E429 IonicContact ND1-OE1 2.69Å; H425-E429 IonicContact ND1-OE2 2.99Å; H425-E429 PolarHBondContact ND1-OE2 3.45Å; H425-E429 IonicContact NE2-OE1 2.96Å; H425-E429 WeakPolarHBondContact O-CG 3.32Å; H425-E429 PolarHBondContact O-N 2.87Å
426F98.5Very high97.7Very high64 Ų6455.8 Ų55.828%0.28127%0.271SS..Hα-helixtrans-60.6-41.7177.9177.9-95.5000112.5I416 N420 D423 E429 T430I416-F426 HydrophobicContact CB-CE1 3.94Å; I416-F426 HydrophobicContact CB-CZ 4.4Å; I416-F426 HydrophobicContact CD1-CE1 4.38Å; I416-F426 HydrophobicContact CG2-CE1 3.62Å; I416-F426 HydrophobicContact CG2-CZ 3.81Å; N420-F426 HydrophobicContact CB-CD1 3.63Å; N420-F426 HydrophobicContact CB-CE1 3.62Å; D423-F426 HydrophobicContact CB-CB 3.84Å; D423-F426 PolarHBondContact O-N 3.32Å; D423-F426 PolarHBondContact OD1-N 3Å; F426-E429 PolarHBondContact O-N 3.3Å; F426-T430 VanDerWaalsContact O-CB 3.29Å; F426-T430 WeakPolarHBondContact O-CB 3.48Å; F426-T430 PolarHBondContact O-N 2.9Å; F426-T430 PolarHBondContact O-OG1 2.8Å
427M98.5Very high97.7Very high1 Ų158.4 Ų58.41%0.00529%0.285CS..Hα-helixtrans-63-44.9177.3-76.5-55.2-55.600112L322 V325 I394 I416 N420 L421 D423 H425 T430 L431L322-M427 HydrophobicContact CD2-CE 4.41Å; V325-M427 HydrophobicContact CG2-CB 3.77Å; I394-M427 HydrophobicContact CD1-CE 4.25Å; I416-M427 HydrophobicContact CD1-CE 3.91Å; I416-M427 HydrophobicContact CD1-SD 3.28Å; I416-M427 WeakPolarHBondContact CD1-SD 3.33Å; N420-M427 WeakPolarHBondContact O-CG 3.49Å; L421-M427 HydrophobicContact CD2-CE 3.94Å; L421-M427 HydrophobicContact CD2-SD 4.03Å; D423-M427 WeakPolarHBondContact O-CB 3.19Å; D423-M427 WeakPolarHBondContact O-CG 3.14Å; D423-M427 PolarHBondContact O-N 3.37Å; H425-M427 VanDerWaalsContact C-N 3.33Å; H425-M427 PolarHBondContact O-N 3.46Å; M427-T430 PolarHBondContact O-N 3.24Å; M427-L431 WeakPolarHBondContact O-CG 3.44Å; M427-L431 PolarHBondContact O-N 2.96Å
428K98.5Very high97.9Very high61 Ų6155.6 Ų55.627%0.26528%0.278SS..Hα-helixtrans-60.9-51.6175.4-177.4-175-177162.40111.4V325 S328 M329 T424 H425 T430 L431 E432V325-K428 HydrophobicContact CG2-CB 4.34Å; S328-K428 PolarHBondContact O-NZ 2.86Å; S328-K428 WeakPolarHBondContact OG-CD 3.43Å; S328-K428 PolarHBondContact OG-NZ 2.79Å; M329-K428 HydrophobicContact CG-CG 4.38Å; M329-K428 HydrophobicContact SD-CG 4.21Å; T424-K428 WeakPolarHBondContact O-CB 3.33Å; T424-K428 PolarHBondContact O-N 3.47Å; H425-K428 PolarHBondContact O-N 3.38Å; K428-T430 VanDerWaalsContact C-N 3.27Å; K428-T430 PolarHBondContact O-N 3.28Å; K428-L431 PolarHBondContact O-N 3.26Å; K428-E432 WeakPolarHBondContact CE-OE1 3.33Å; K428-E432 HydrophobicContact CG-CG 4.36Å; K428-E432 WeakPolarHBondContact O-CB 3.43Å; K428-E432 WeakPolarHBondContact O-CG 3.09Å; K428-E432 PolarHBondContact O-N 2.9Å
429E98.5Very high98Very high102 Ų10259.9 Ų59.948%0.47730%0.297SS..Hα-helixtrans-59.1-40.7-179.8-75.3-170141.400111.8H425 F426 E432 K433H425-E429 IonicContact CE1-OE1 3.41Å; H425-E429 PolarHBondContact CE1-OE1 2.97Å; H425-E429 IonicContact CE1-OE2 3.82Å; H425-E429 PolarHBondContact CE1-OE2 3.47Å; H425-E429 VanDerWaalsContact CE1-OE2 3.32Å; H425-E429 IonicContact ND1-OE1 2.69Å; H425-E429 IonicContact ND1-OE2 2.99Å; H425-E429 PolarHBondContact ND1-OE2 3.45Å; H425-E429 IonicContact NE2-OE1 2.96Å; H425-E429 WeakPolarHBondContact O-CG 3.32Å; H425-E429 PolarHBondContact O-N 2.87Å; F426-E429 PolarHBondContact O-N 3.3Å; E429-E432 PolarHBondContact O-N 3.07Å; E429-K433 WeakPolarHBondContact O-CB 3.41Å; E429-K433 PolarHBondContact O-N 2.87Å
430T98.7Very high98.2Very high10 Ų1056.2 Ų56.26%0.06128%0.276CS..Hα-helixtrans-63.6-47.3177.5-63.20000111.4V392 V414 I416 F426 M427 K428 K433 V434V392-T430 HydrophobicContact CG1-CG2 4.06Å; V392-T430 HydrophobicContact CG2-CG2 3.94Å; V414-T430 HydrophobicContact CB-CG2 4.38Å; V414-T430 HydrophobicContact CG1-CG2 4.07Å; I416-T430 HydrophobicContact CG2-CG2 4.13Å; F426-T430 VanDerWaalsContact O-CB 3.29Å; F426-T430 WeakPolarHBondContact O-CB 3.48Å; F426-T430 PolarHBondContact O-N 2.9Å; F426-T430 PolarHBondContact O-OG1 2.8Å; M427-T430 PolarHBondContact O-N 3.24Å; K428-T430 VanDerWaalsContact C-N 3.27Å; K428-T430 PolarHBondContact O-N 3.28Å; T430-K433 PolarHBondContact O-N 3.42Å; T430-V434 WeakPolarHBondContact O-CG2 3.46Å; T430-V434 PolarHBondContact O-N 2.84Å
431L98.7Very high98.3Very high2 Ų257.3 Ų57.31%0.0128%0.281CS..Hα-helixtrans-62.6-47.1176.8-76.6170.8000111.7V301 V325 M329 F334 V371 V373 V392 M427 K428 K433 V434 I435V301-L431 HydrophobicContact CG1-CD2 4.17Å; V301-L431 HydrophobicContact CG2-CD2 4.44Å; V325-L431 HydrophobicContact CG1-CD1 3.83Å; M329-L431 HydrophobicContact CE-CB 4.4Å; M329-L431 HydrophobicContact SD-CD1 4.46Å; F334-L431 HydrophobicContact CE1-CD1 4.21Å; V371-L431 HydrophobicContact CG1-CD2 4.31Å; V373-L431 HydrophobicContact CG2-CD2 3.75Å; V392-L431 HydrophobicContact CG2-CD2 4.19Å; M427-L431 WeakPolarHBondContact O-CG 3.44Å; M427-L431 PolarHBondContact O-N 2.96Å; K428-L431 PolarHBondContact O-N 3.26Å; L431-K433 VanDerWaalsContact C-N 3.3Å; L431-K433 PolarHBondContact O-N 3.2Å; L431-V434 PolarHBondContact O-N 2.94Å; L431-I435 WeakPolarHBondContact O-CB 3.32Å; L431-I435 WeakPolarHBondContact O-CD1 3.4Å; L431-I435 WeakPolarHBondContact O-CG1 3.39Å; L431-I435 PolarHBondContact O-N 2.87Å
432E98.5Very high98.4Very high55 Ų5563.2 Ų63.226%0.25731%0.309SS..Hα-helixtrans-60.5-40.5177.7-74.4-167.8176.200112.1M329 K428 E429 I435 K436M329-E432 HydrophobicContact CE-CG 4.04Å; K428-E432 WeakPolarHBondContact CE-OE1 3.33Å; K428-E432 HydrophobicContact CG-CG 4.36Å; K428-E432 WeakPolarHBondContact O-CB 3.43Å; K428-E432 WeakPolarHBondContact O-CG 3.09Å; K428-E432 PolarHBondContact O-N 2.9Å; E429-E432 PolarHBondContact O-N 3.07Å; E432-I435 PolarHBondContact O-N 2.84Å; E432-K436 HydrophobicContact CB-CD 4.27Å; E432-K436 VanDerWaalsContact CD-NZ 3.28Å; E432-K436 WeakPolarHBondContact O-CB 3.26Å; E432-K436 WeakPolarHBondContact O-CG 3.35Å; E432-K436 PolarHBondContact O-N 3.17Å; E432-K436 IonicContact OE1-NZ 3.83Å; E432-K436 IonicContact OE2-NZ 2.69Å; E432-K436 PolarHBondContact OE2-NZ 2.85Å
433K98.6Very high98.5Very high114 Ų11463.7 Ų63.750%0.49631%0.308SS..Hα-helixtrans-60.1-49.6176-176.9-171.1-172.9-1710111.4E429 T430 L431 I435 K436 D437 Y440E429-K433 WeakPolarHBondContact O-CB 3.41Å; E429-K433 PolarHBondContact O-N 2.87Å; T430-K433 PolarHBondContact O-N 3.42Å; L431-K433 VanDerWaalsContact C-N 3.3Å; L431-K433 PolarHBondContact O-N 3.2Å; K433-I435 VanDerWaalsContact C-N 3.33Å; K433-I435 PolarHBondContact O-N 3.09Å; K433-K436 PolarHBondContact O-N 3.23Å; K433-D437 VanDerWaalsContact O-CB 3.24Å; K433-D437 WeakPolarHBondContact O-CB 3.23Å; K433-D437 PolarHBondContact O-N 2.81Å; K433-Y440 VanDerWaalsContact CE-OH 3.27Å; K433-Y440 WeakPolarHBondContact CE-OH 3.22Å; K433-Y440 HydrophobicContact CG-CE2 4.16Å
434V98.7Very high98.5Very high4 Ų460.3 Ų60.32%0.02429%0.29CS..Hα-helixtrans-68.1-34.3-178.7-177.80000111.6V371 P390 V392 V414 T430 L431 Y440V371-V434 HydrophobicContact CG1-CG1 4.1Å; V371-V434 HydrophobicContact CG2-CB 4.07Å; V371-V434 HydrophobicContact CG2-CG1 3.6Å; P390-V434 HydrophobicContact CB-CG1 3.6Å; V392-V434 HydrophobicContact CG2-CB 4.47Å; V392-V434 HydrophobicContact CG2-CG2 3.95Å; V414-V434 HydrophobicContact CB-CG2 4.32Å; V414-V434 HydrophobicContact CG2-CG2 3.62Å; T430-V434 WeakPolarHBondContact O-CG2 3.46Å; T430-V434 PolarHBondContact O-N 2.84Å; L431-V434 PolarHBondContact O-N 2.94Å; V434-Y440 HydrophobicContact CB-CD2 4.4Å; V434-Y440 HydrophobicContact CG1-CD1 4.36Å; V434-Y440 HydrophobicContact CG1-CD2 4.39Å; V434-Y440 HydrophobicContact CG1-CG 4.05Å; V434-Y440 HydrophobicContact CG2-CD1 4.44Å; V434-Y440 HydrophobicContact CG2-CD2 4.44Å; V434-Y440 HydrophobicContact CG2-CE1 4.29Å; V434-Y440 HydrophobicContact CG2-CE2 4.29Å
435I98.4Very high98.5Very high38 Ų3864 Ų6420%0.19530%0.303CS..Hα-helixtrans-70.6-42176-69.1165.9000111.9N299 V301 M329 V371 L431 E432 K433N299-I435 HydrophobicContact CB-CD1 4.45Å; N299-I435 HydrophobicContact CB-CG2 4.38Å; V301-I435 HydrophobicContact CG2-CD1 4.06Å; M329-I435 HydrophobicContact CE-CD1 4.06Å; V371-I435 HydrophobicContact CG2-CG1 3.54Å; L431-I435 WeakPolarHBondContact O-CB 3.32Å; L431-I435 WeakPolarHBondContact O-CD1 3.4Å; L431-I435 WeakPolarHBondContact O-CG1 3.39Å; L431-I435 PolarHBondContact O-N 2.87Å; E432-I435 PolarHBondContact O-N 2.84Å; K433-I435 VanDerWaalsContact C-N 3.33Å; K433-I435 PolarHBondContact O-N 3.09Å
436K98.1Very high98.5Very high139 Ų13965.5 Ų65.560%0.60430%0.303SS*.Hα-helixtrans-90.9-32.5-169.2-66.6170.6-176.7171.50113.8E432 K433 P438E432-K436 HydrophobicContact CB-CD 4.27Å; E432-K436 VanDerWaalsContact CD-NZ 3.28Å; E432-K436 WeakPolarHBondContact O-CB 3.26Å; E432-K436 WeakPolarHBondContact O-CG 3.35Å; E432-K436 PolarHBondContact O-N 3.17Å; E432-K436 IonicContact OE1-NZ 3.83Å; E432-K436 IonicContact OE2-NZ 2.69Å; E432-K436 PolarHBondContact OE2-NZ 2.85Å; K433-K436 PolarHBondContact O-N 3.23Å; K436-P438 VanDerWaalsContact O-CD 3.31Å; K436-P438 WeakPolarHBondContact O-CD 3.28Å
437D98.5Very high98.5Very high61 Ų6162.6 Ų62.633%0.32629%0.291SS..  trans-80.2110.8-179.6-177.9-7.4000110.1K433 K439 Y440K433-D437 VanDerWaalsContact O-CB 3.24Å; K433-D437 WeakPolarHBondContact O-CB 3.23Å; K433-D437 PolarHBondContact O-N 2.81Å; D437-K439 PolarHBondContact O-N 3Å; D437-K439 WeakPolarHBondContact OD1-CB 3.46Å; D437-K439 PolarHBondContact OD1-N 2.85Å; D437-Y440 HydrophobicContact CB-CD2 3.86Å; D437-Y440 HydrophobicContact CB-CE2 3.9Å; D437-Y440 PolarHBondContact O-N 2.91Å
438P98.1Very high98.4Very high77 Ų7762.9 Ų62.950%0.529%0.293SS..Hα-helixtrans-60.8-22.5-175.526-35.3000112.9K436 Y440 L441 E442K436-P438 VanDerWaalsContact O-CD 3.31Å; K436-P438 WeakPolarHBondContact O-CD 3.28Å; P438-Y440 PolarHBondContact O-N 3.12Å; P438-L441 PolarHBondContact O-N 2.88Å; P438-L441 VanDerWaalsContact O-N 3.14Å; P438-E442 WeakPolarHBondContact O-CB 3.14Å; P438-E442 WeakPolarHBondContact O-CG 3.4Å; P438-E442 PolarHBondContact O-N 2.9Å
439K98.5Very high98.3Very high118 Ų11866 Ų6651%0.51331%0.309SS..Hα-helixtrans-55.1-37.8180179.8179.1175.1-174.90112.6D437 N443D437-K439 PolarHBondContact O-N 3Å; D437-K439 WeakPolarHBondContact OD1-CB 3.46Å; D437-K439 PolarHBondContact OD1-N 2.85Å; K439-N443 WeakPolarHBondContact CG-ND2 3.28Å; K439-N443 WeakPolarHBondContact O-CB 3.29Å; K439-N443 PolarHBondContact O-N 3.05Å; K439-N443 PolarHBondContact O-ND2 2.75Å
440Y98.8Very high98.2Very high23 Ų2364 Ų649%0.0930%0.3CS..Hα-helixtrans-65.7-46.1-180-67.1-81000111.3G411 V414 K433 V434 D437 P438 S444G411-Y440 WeakPolarHBondContact O-CD1 3.46Å; V414-Y440 HydrophobicContact CG2-CE1 3.51Å; V414-Y440 VanDerWaalsContact CG2-OH 3.32Å; V414-Y440 WeakPolarHBondContact CG2-OH 3.48Å; K433-Y440 VanDerWaalsContact CE-OH 3.27Å; K433-Y440 WeakPolarHBondContact CE-OH 3.22Å; K433-Y440 HydrophobicContact CG-CE2 4.16Å; V434-Y440 HydrophobicContact CB-CD2 4.4Å; V434-Y440 HydrophobicContact CG1-CD1 4.36Å; V434-Y440 HydrophobicContact CG1-CD2 4.39Å; V434-Y440 HydrophobicContact CG1-CG 4.05Å; V434-Y440 HydrophobicContact CG2-CD1 4.44Å; V434-Y440 HydrophobicContact CG2-CD2 4.44Å; V434-Y440 HydrophobicContact CG2-CE1 4.29Å; V434-Y440 HydrophobicContact CG2-CE2 4.29Å; D437-Y440 HydrophobicContact CB-CD2 3.86Å; D437-Y440 HydrophobicContact CB-CE2 3.9Å; D437-Y440 PolarHBondContact O-N 2.91Å; P438-Y440 PolarHBondContact O-N 3.12Å; Y440-S444 WeakPolarHBondContact O-CB 3.26Å; Y440-S444 PolarHBondContact O-N 2.78Å; Y440-S444 PolarHBondContact O-OG 2.99Å; Y440-S444 VanDerWaalsContact O-OG 3.09Å
441L98.6Very high98.1Very high71 Ų7163.7 Ų63.737%0.37230%0.298SS..Hα-helixtrans-68-42.8178.7-176.161.6000112.2P390 P438 S444 K445P390-L441 HydrophobicContact CG-CB 4.07Å; P390-L441 HydrophobicContact CG-CD1 3.98Å; P438-L441 PolarHBondContact O-N 2.88Å; P438-L441 VanDerWaalsContact O-N 3.14Å; L441-S444 PolarHBondContact O-N 2.81Å; L441-K445 HydrophobicContact CD1-CD 4.33Å; L441-K445 HydrophobicContact CD1-CG 4.33Å; L441-K445 HydrophobicContact CG-CD 4.16Å; L441-K445 WeakPolarHBondContact O-CB 3.48Å; L441-K445 VanDerWaalsContact O-CG 3.31Å; L441-K445 WeakPolarHBondContact O-CG 3.42Å; L441-K445 PolarHBondContact O-N 3.44Å
442E98.7Very high97.7Very high124 Ų12467 Ų6758%0.57932%0.319SS*.Hα-helixtrans-60.2-46.5177.4-73174.3-176.100111.5P438 K445 R446P438-E442 WeakPolarHBondContact O-CB 3.14Å; P438-E442 WeakPolarHBondContact O-CG 3.4Å; P438-E442 PolarHBondContact O-N 2.9Å; E442-K445 PolarHBondContact O-N 3.5Å; E442-R446 WeakPolarHBondContact O-CB 3.35Å; E442-R446 PolarHBondContact O-N 2.73Å
443N98.8Very high97.5Very high36 Ų3670 Ų7019%0.19334%0.337CS..Hα-helixtrans-66.6-42.6177.9-76.2-29000112.6H410 G411 K439 K445 R446 L447H410-N443 VanDerWaalsContact O-CB 3.26Å; H410-N443 WeakPolarHBondContact O-CB 3.36Å; G411-N443 PolarHBondContact O-ND2 2.96Å; G411-N443 VanDerWaalsContact O-ND2 3.09Å; K439-N443 WeakPolarHBondContact CG-ND2 3.28Å; K439-N443 WeakPolarHBondContact O-CB 3.29Å; K439-N443 PolarHBondContact O-N 3.05Å; K439-N443 PolarHBondContact O-ND2 2.75Å; N443-K445 VanDerWaalsContact C-N 3.34Å; N443-K445 PolarHBondContact O-N 3.46Å; N443-R446 PolarHBondContact O-N 3.01Å; N443-L447 WeakPolarHBondContact O-CB 3.46Å; N443-L447 PolarHBondContact O-N 3.5Å
444S98.6Very high97.2Very high3 Ų366.6 Ų66.62%0.02132%0.322CS..Hα-helixtrans-62.8-41.5176.1-67.90000111.5G388 T389 G412 Y440 L441 L447 A448G388-S444 VanDerWaalsContact C-CB 3.48Å; G388-S444 WeakPolarHBondContact CA-O 3.39Å; G388-S444 WeakPolarHBondContact O-CB 3.47Å; T389-S444 PolarHBondContact O-OG 3Å; G412-S444 VanDerWaalsContact CA-OG 3.31Å; G412-S444 WeakPolarHBondContact CA-OG 3.3Å; G412-S444 PolarHBondContact O-OG 3.14Å; Y440-S444 WeakPolarHBondContact O-CB 3.26Å; Y440-S444 PolarHBondContact O-N 2.78Å; Y440-S444 PolarHBondContact O-OG 2.99Å; Y440-S444 VanDerWaalsContact O-OG 3.09Å; L441-S444 PolarHBondContact O-N 2.81Å; S444-L447 PolarHBondContact O-N 3.48Å; S444-A448 WeakPolarHBondContact O-CB 3.41Å; S444-A448 PolarHBondContact O-N 3Å
445K98.2Very high96.9Very high122 Ų12272.6 Ų72.653%0.5336%0.361SS..Hα-helixtrans-64.3-44.4175.4-76.4176.9176.7175.10112.4L441 E442 N443 L447 A448 E449L441-K445 HydrophobicContact CD1-CD 4.33Å; L441-K445 HydrophobicContact CD1-CG 4.33Å; L441-K445 HydrophobicContact CG-CD 4.16Å; L441-K445 WeakPolarHBondContact O-CB 3.48Å; L441-K445 VanDerWaalsContact O-CG 3.31Å; L441-K445 WeakPolarHBondContact O-CG 3.42Å; L441-K445 PolarHBondContact O-N 3.44Å; E442-K445 PolarHBondContact O-N 3.5Å; N443-K445 VanDerWaalsContact C-N 3.34Å; N443-K445 PolarHBondContact O-N 3.46Å; K445-L447 VanDerWaalsContact C-N 3.32Å; K445-L447 PolarHBondContact O-N 2.97Å; K445-A448 PolarHBondContact O-N 3.17Å; K445-E449 PolarHBondContact O-N 3.42Å
446R98.4Very high96.6Very high150 Ų15075 Ų7557%0.56638%0.378SS*.Hα-helixtrans-60.2-42.6175.6179.3176.3173.7-100.7-5.5111.5E442 N443 E449 M450E442-R446 WeakPolarHBondContact O-CB 3.35Å; E442-R446 PolarHBondContact O-N 2.73Å; N443-R446 PolarHBondContact O-N 3.01Å; R446-E449 PolarHBondContact O-N 3.01Å; R446-M450 HydrophobicContact CG-CE 4.46Å; R446-M450 WeakPolarHBondContact O-CG 3.46Å; R446-M450 PolarHBondContact O-N 3.01Å; R446-M450 VanDerWaalsContact O-N 3.11Å
447L98.3Very high96.4Very high3 Ų371.6 Ų71.62%0.01637%0.366CS..Hα-helixtrans-62.7-47.817517960.6000111.3L259 A385 L407 H410 N443 S444 K445 E449 M450 L451L259-L447 HydrophobicContact CD1-CD1 4.47Å; L259-L447 HydrophobicContact CD1-CD2 3.92Å; A385-L447 HydrophobicContact CB-CD2 3.95Å; L407-L447 HydrophobicContact CD1-CD2 3.96Å; H410-L447 HydrophobicContact CB-CD2 3.92Å; N443-L447 WeakPolarHBondContact O-CB 3.46Å; N443-L447 PolarHBondContact O-N 3.5Å; S444-L447 PolarHBondContact O-N 3.48Å; K445-L447 VanDerWaalsContact C-N 3.32Å; K445-L447 PolarHBondContact O-N 2.97Å; L447-E449 VanDerWaalsContact C-N 3.29Å; L447-E449 PolarHBondContact O-N 3.5Å; L447-M450 HydrophobicContact CB-CE 4.45Å; L447-M450 HydrophobicContact CD1-CE 3.97Å; L447-M450 WeakPolarHBondContact O-CB 3.47Å; L447-M450 PolarHBondContact O-N 3.46Å; L447-M450 VanDerWaalsContact O-N 3.11Å; L447-L451 HydrophobicContact CD1-CD1 3.94Å; L447-L451 HydrophobicContact CD1-CD2 4.22Å; L447-L451 HydrophobicContact CD1-CG 3.9Å; L447-L451 HydrophobicContact CD2-CD1 4.49Å; L447-L451 HydrophobicContact CG-CD1 3.85Å; L447-L451 HydrophobicContact CG-CG 4.19Å; L447-L451 VanDerWaalsContact O-CG 3.3Å; L447-L451 WeakPolarHBondContact O-CG 3.09Å; L447-L451 PolarHBondContact O-N 3.15Å
448A96.6Very high96.2Very high7 Ų770.1 Ų70.16%0.05836%0.36CS..Hα-helixtrans-57.9-41.2176.900000112.6A385 M386 S444 K445 L451 T452A385-A448 VanDerWaalsContact O-CA 3.24Å; A385-A448 WeakPolarHBondContact O-CA 3.44Å; A385-A448 WeakPolarHBondContact O-CB 3.01Å; A385-A448 PolarHBondContact O-N 3.49Å; M386-A448 WeakPolarHBondContact O-CB 3.04Å; S444-A448 WeakPolarHBondContact O-CB 3.41Å; S444-A448 PolarHBondContact O-N 3Å; K445-A448 PolarHBondContact O-N 3.17Å; A448-L451 PolarHBondContact O-N 2.93Å; A448-T452 WeakPolarHBondContact O-CB 3.33Å; A448-T452 WeakPolarHBondContact O-CG2 3.45Å; A448-T452 PolarHBondContact O-N 2.69Å; A448-T452 PolarHBondContact O-OG1 2.89Å
449E96.4Very high96.2Very high128 Ų12871.4 Ų71.460%0.59836%0.358SS*.Hα-helixtrans-59.9-45.5174.8-174.2177.3-165.900111.5K445 R446 L447 T452 N453K445-E449 PolarHBondContact O-N 3.42Å; R446-E449 PolarHBondContact O-N 3.01Å; L447-E449 VanDerWaalsContact C-N 3.29Å; L447-E449 PolarHBondContact O-N 3.5Å; E449-T452 PolarHBondContact O-OG1 3.35Å; E449-N453 WeakPolarHBondContact O-CB 3.45Å; E449-N453 PolarHBondContact O-N 3.19Å; E449-N453 PolarHBondContact O-ND2 3.21Å
450M96.8Very high96.1Very high59 Ų5970.2 Ų70.229%0.29135%0.354SS..Hα-helixtrans-63.3-43.9175.2-67.9-174.4-63.200112.4L258 R446 L447 N453 Q454L258-M450 HydrophobicContact CD1-CB 4.35Å; R446-M450 HydrophobicContact CG-CE 4.46Å; R446-M450 WeakPolarHBondContact O-CG 3.46Å; R446-M450 PolarHBondContact O-N 3.01Å; R446-M450 VanDerWaalsContact O-N 3.11Å; L447-M450 HydrophobicContact CB-CE 4.45Å; L447-M450 HydrophobicContact CD1-CE 3.97Å; L447-M450 WeakPolarHBondContact O-CB 3.47Å; L447-M450 PolarHBondContact O-N 3.46Å; L447-M450 VanDerWaalsContact O-N 3.11Å; M450-N453 CarbonylContact O-C 3.4Å; M450-N453 PolarHBondContact O-N 3.5Å; M450-Q454 PolarHBondContact O-N 2.8Å
451L95.3Very high96.1Very high3 Ų370 Ų702%0.01636%0.355CS..Hα-helixtrans-72.7-27.8-176.4-62.6-179.9000113.3I256 L258 L259 A385 M386 L447 A448 Q454I256-L451 HydrophobicContact CG2-CD2 3.56Å; L258-L451 HydrophobicContact CB-CD2 3.91Å; L259-L451 HydrophobicContact CB-CD2 4.07Å; L259-L451 HydrophobicContact CD2-CD1 4.45Å; A385-L451 HydrophobicContact CB-CD1 3.66Å; M386-L451 HydrophobicContact CG-CB 4.18Å; M386-L451 HydrophobicContact CG-CD1 4.16Å; L447-L451 HydrophobicContact CD1-CD1 3.94Å; L447-L451 HydrophobicContact CD1-CD2 4.22Å; L447-L451 HydrophobicContact CD1-CG 3.9Å; L447-L451 HydrophobicContact CD2-CD1 4.49Å; L447-L451 HydrophobicContact CG-CD1 3.85Å; L447-L451 HydrophobicContact CG-CG 4.19Å; L447-L451 VanDerWaalsContact O-CG 3.3Å; L447-L451 WeakPolarHBondContact O-CG 3.09Å; L447-L451 PolarHBondContact O-N 3.15Å; A448-L451 PolarHBondContact O-N 2.93Å; L451-Q454 WeakPolarHBondContact O-CG 3.42Å; L451-Q454 PolarHBondContact O-NE2 2.99Å
452T91.7Very high96.1Very high73 Ų7366.7 Ų66.745%0.44834%0.338SS..Hα-helixtrans-85.4-16.9176.552.70000113.2A448 E449A448-T452 WeakPolarHBondContact O-CB 3.33Å; A448-T452 WeakPolarHBondContact O-CG2 3.45Å; A448-T452 PolarHBondContact O-N 2.69Å; A448-T452 PolarHBondContact O-OG1 2.89Å; E449-T452 PolarHBondContact O-OG1 3.35Å
453N92.8Very high96Very high118 Ų11862.4 Ų62.463%0.63132%0.319SS*.THydrogen-bonded Turntrans-111.834.1176.3-65.7-81.1000112.4E449 M450E449-N453 WeakPolarHBondContact O-CB 3.45Å; E449-N453 PolarHBondContact O-N 3.19Å; E449-N453 PolarHBondContact O-ND2 3.21Å; M450-N453 CarbonylContact O-C 3.4Å; M450-N453 PolarHBondContact O-N 3.5Å
454Q92.9Very high96Very high42 Ų4266.8 Ų66.820%0.19634%0.336CS..  trans-62.3144.3176.2-74.5179.883.600111.4I256 L258 M450 L451 T456I256-Q454 VanDerWaalsContact CG2-OE1 3.23Å; L258-Q454 HydrophobicContact CD1-CG 3.99Å; M450-Q454 PolarHBondContact O-N 2.8Å; L451-Q454 WeakPolarHBondContact O-CG 3.42Å; L451-Q454 PolarHBondContact O-NE2 2.99Å; Q454-T456 PolarHBondContact O-N 2.99Å
455P92.7Very high96Very high130 Ų13070.7 Ų70.784%0.84435%0.351SS*.SBendtrans-63.7-22.5179.4-23.934.2000114.6
456T91.5Very high96Very high88 Ų8864.9 Ų64.954%0.5433%0.325SS..SBendtrans-120.5147.5-177.955.30000111.1Q454Q454-T456 PolarHBondContact O-N 2.99Å
457N93.9Very high96Very high68 Ų6860.4 Ų60.436%0.36431%0.311SS..  trans-95.7115.9173.8178.3-18.1000109.1K459 E460 T461N457-K459 PolarHBondContact O-N 2.83Å; N457-K459 WeakPolarHBondContact OD1-CB 3.46Å; N457-K459 PolarHBondContact OD1-N 3.07Å; N457-E460 HydrophobicContact CB-CB 4.12Å; N457-E460 HydrophobicContact CB-CG 4.03Å; N457-E460 PolarHBondContact ND2-OE1 3.35Å; N457-E460 PolarHBondContact O-N 2.9Å; N457-E460 VanDerWaalsContact O-N 3.09Å; N457-T461 PolarHBondContact O-N 2.96Å; N457-T461 PolarHBondContact O-OG1 3.27Å; N457-T461 VanDerWaalsContact O-OG1 3.12Å
458P95.7Very high96Very high30 Ų3064.7 Ų64.720%0.19533%0.329CS..Hα-helixtrans-62.7-27.6-174.425.6-35.2000113.2L275 L462L275-P458 HydrophobicContact CD2-CB 3.8Å; L275-P458 HydrophobicContact CD2-CG 4.3Å; P458-L462 WeakPolarHBondContact O-CB 3.34Å; P458-L462 PolarHBondContact O-N 3.39Å
459K96.4Very high96.1Very high104 Ų10464.3 Ų64.345%0.45233%0.327SS..Hα-helixtrans-68.2-45.3175-56.4-171177.1-179.90111.4I43 L275 N457 T461 L462 I463I43-K459 HydrophobicContact CD1-CB 4.28Å; I43-K459 HydrophobicContact CD1-CD 4.09Å; I43-K459 HydrophobicContact CD1-CG 3.77Å; I43-K459 HydrophobicContact CG1-CD 4.23Å; I43-K459 HydrophobicContact CG1-CG 4.33Å; I43-K459 HydrophobicContact CG2-CB 4.14Å; L275-K459 HydrophobicContact CD2-CG 4.09Å; N457-K459 PolarHBondContact O-N 2.83Å; N457-K459 WeakPolarHBondContact OD1-CB 3.46Å; N457-K459 PolarHBondContact OD1-N 3.07Å; K459-T461 VanDerWaalsContact C-N 3.34Å; K459-L462 PolarHBondContact O-N 3.24Å; K459-I463 WeakPolarHBondContact O-CD1 3.32Å; K459-I463 VanDerWaalsContact O-CG1 3.3Å; K459-I463 WeakPolarHBondContact O-CG1 3.23Å; K459-I463 PolarHBondContact O-N 3.11Å; K459-I463 VanDerWaalsContact O-N 3.1Å
460E97.1Very high96.2Very high92 Ų9258.4 Ų58.443%0.4330%0.299SS..Hα-helixtrans-66.5-38.3176.1-69178-146.600111.8N457 I463 K464N457-E460 HydrophobicContact CB-CB 4.12Å; N457-E460 HydrophobicContact CB-CG 4.03Å; N457-E460 PolarHBondContact ND2-OE1 3.35Å; N457-E460 PolarHBondContact O-N 2.9Å; N457-E460 VanDerWaalsContact O-N 3.09Å; E460-I463 PolarHBondContact O-N 2.9Å; E460-K464 WeakPolarHBondContact O-CB 3.41Å; E460-K464 VanDerWaalsContact O-CG 3.28Å; E460-K464 WeakPolarHBondContact O-CG 3.27Å; E460-K464 PolarHBondContact O-N 3.06Å; E460-K464 IonicContact OE2-NZ 2.67Å; E460-K464 PolarHBondContact OE2-NZ 3.39Å
461T98.1Very high96.2Very high20 Ų2063.2 Ų63.212%0.12331%0.314CS..Hα-helixtrans-58.8-51.1173.8-600000110.3V270 I272 N457 K459 I463 K464 Y465V270-T461 HydrophobicContact CG1-CG2 3.49Å; V270-T461 VanDerWaalsContact CG1-CG2 3.49Å; I272-T461 HydrophobicContact CG2-CG2 3.97Å; N457-T461 PolarHBondContact O-N 2.96Å; N457-T461 PolarHBondContact O-OG1 3.27Å; N457-T461 VanDerWaalsContact O-OG1 3.12Å; K459-T461 VanDerWaalsContact C-N 3.34Å; T461-I463 PolarHBondContact O-N 2.96Å; T461-K464 PolarHBondContact O-N 2.93Å; T461-Y465 HydrophobicContact CG2-CD2 3.67Å; T461-Y465 HydrophobicContact CG2-CE2 3.79Å; T461-Y465 WeakPolarHBondContact O-CB 3.44Å; T461-Y465 VanDerWaalsContact O-CD2 3.28Å; T461-Y465 WeakPolarHBondContact O-CD2 3.5Å; T461-Y465 PolarHBondContact O-N 3.15Å
462L98.5Very high96.3Very high0 Ų068 Ų680%034%0.335CS..Hα-helixtrans-51.9-53.6176170.365.7000111.3A40 I43 L44 I168 L252 I272 L275 P458 K459 Y465 V466A40-L462 HydrophobicContact CB-CD2 3.8Å; I43-L462 HydrophobicContact CB-CD2 4.09Å; I43-L462 HydrophobicContact CD1-CD2 4.3Å; I43-L462 HydrophobicContact CG2-CD2 3.93Å; L44-L462 HydrophobicContact CD2-CG 4.34Å; L44-L462 HydrophobicContact CG-CD2 4.41Å; I168-L462 HydrophobicContact CD1-CD1 4.23Å; L252-L462 HydrophobicContact CD1-CD1 3.56Å; I272-L462 HydrophobicContact CD1-CD1 4.27Å; I272-L462 HydrophobicContact CG2-CB 4.33Å; L275-L462 HydrophobicContact CD1-CD2 3.69Å; P458-L462 WeakPolarHBondContact O-CB 3.34Å; P458-L462 PolarHBondContact O-N 3.39Å; K459-L462 PolarHBondContact O-N 3.24Å; L462-Y465 PolarHBondContact O-N 3.25Å; L462-V466 HydrophobicContact CD1-CG2 3.66Å; L462-V466 HydrophobicContact CG-CG2 4.43Å; L462-V466 VanDerWaalsContact O-CB 3.28Å; L462-V466 WeakPolarHBondContact O-CB 3.46Å; L462-V466 VanDerWaalsContact O-CG2 3.22Å; L462-V466 WeakPolarHBondContact O-CG2 3.44Å; L462-V466 PolarHBondContact O-N 2.95Å
463I98.4Very high96.6Very high35 Ų3564.6 Ų64.618%0.17932%0.315CS..Hα-helixtrans-57.5-54.4-178.2-65.4160.4000110.5I43 L44 A47 K459 E460 T461 Y465 V466 E467I43-I463 HydrophobicContact CG2-CD1 3.83Å; I43-I463 HydrophobicContact CG2-CG1 3.77Å; L44-I463 HydrophobicContact CD2-CG1 4.44Å; A47-I463 HydrophobicContact CB-CD1 3.68Å; A47-I463 HydrophobicContact CB-CG1 3.87Å; A47-I463 HydrophobicContact CB-CG2 4.02Å; K459-I463 WeakPolarHBondContact O-CD1 3.32Å; K459-I463 VanDerWaalsContact O-CG1 3.3Å; K459-I463 WeakPolarHBondContact O-CG1 3.23Å; K459-I463 PolarHBondContact O-N 3.11Å; K459-I463 VanDerWaalsContact O-N 3.1Å; E460-I463 PolarHBondContact O-N 2.9Å; T461-I463 PolarHBondContact O-N 2.96Å; I463-Y465 PolarHBondContact O-N 3.08Å; I463-V466 PolarHBondContact O-N 3.41Å; I463-E467 HydrophobicContact CG2-CG 4.25Å; I463-E467 WeakPolarHBondContact CG2-OE1 3.41Å; I463-E467 WeakPolarHBondContact O-CB 3.27Å; I463-E467 VanDerWaalsContact O-CG 3.3Å; I463-E467 WeakPolarHBondContact O-CG 2.98Å; I463-E467 PolarHBondContact O-N 3.5Å
464K98.1Very high96.9Very high127 Ų12762.8 Ų62.855%0.55230%0.301SS*.Hα-helixtrans-60-43.2-175.4-73.2168.5-178.81610112.4E460 T461 F468E460-K464 WeakPolarHBondContact O-CB 3.41Å; E460-K464 VanDerWaalsContact O-CG 3.28Å; E460-K464 WeakPolarHBondContact O-CG 3.27Å; E460-K464 PolarHBondContact O-N 3.06Å; E460-K464 IonicContact OE2-NZ 2.67Å; E460-K464 PolarHBondContact OE2-NZ 3.39Å; T461-K464 PolarHBondContact O-N 2.93Å; K464-F468 WeakPolarHBondContact O-CB 3.08Å; K464-F468 PolarHBondContact O-N 3.36Å
465Y98.7Very high97.1Very high85 Ų8562.1 Ų62.133%0.33330%0.299SS..Hα-helixtrans-73.4-37.9-179.1-83.9-92000112.5F250 V270 T461 L462 I463 A469F250-Y465 AromaticContact CD1-CD1 3.58Å; F250-Y465 HydrophobicContact CD1-CD1 3.58Å; F250-Y465 AromaticContact CD1-CE1 3.84Å; F250-Y465 HydrophobicContact CD1-CE1 3.84Å; F250-Y465 AromaticContact CD2-CD1 3.72Å; F250-Y465 HydrophobicContact CD2-CD1 3.72Å; F250-Y465 HydrophobicContact CD2-CG 4.45Å; F250-Y465 AromaticContact CE1-CD1 3.52Å; F250-Y465 HydrophobicContact CE1-CD1 3.52Å; F250-Y465 AromaticContact CE1-CE1 3.58Å; F250-Y465 HydrophobicContact CE1-CE1 3.58Å; F250-Y465 AromaticContact CE2-CD1 3.65Å; F250-Y465 HydrophobicContact CE2-CD1 3.65Å; F250-Y465 HydrophobicContact CE2-CE1 4.47Å; F250-Y465 HydrophobicContact CE2-CG 4.49Å; F250-Y465 AromaticContact CG-CD1 3.68Å; F250-Y465 HydrophobicContact CG-CD1 3.68Å; F250-Y465 HydrophobicContact CG-CE1 4.4Å; F250-Y465 AromaticContact CZ-CD1 3.55Å; F250-Y465 HydrophobicContact CZ-CD1 3.55Å; F250-Y465 AromaticContact CZ-CE1 3.92Å; F250-Y465 HydrophobicContact CZ-CE1 3.92Å; V270-Y465 HydrophobicContact CB-CD1 4.48Å; V270-Y465 HydrophobicContact CB-CE1 4.41Å; V270-Y465 HydrophobicContact CG1-CD1 4.22Å; V270-Y465 HydrophobicContact CG1-CD2 3.78Å; V270-Y465 HydrophobicContact CG1-CE1 4.15Å; V270-Y465 HydrophobicContact CG1-CE2 3.69Å; V270-Y465 HydrophobicContact CG1-CG 4.03Å; V270-Y465 HydrophobicContact CG2-CD1 3.65Å; V270-Y465 HydrophobicContact CG2-CE1 3.38Å; V270-Y465 HydrophobicContact CG2-CE2 4.43Å; V270-Y465 HydrophobicContact CG2-CG 4.28Å; T461-Y465 HydrophobicContact CG2-CD2 3.67Å; T461-Y465 HydrophobicContact CG2-CE2 3.79Å; T461-Y465 WeakPolarHBondContact O-CB 3.44Å; T461-Y465 VanDerWaalsContact O-CD2 3.28Å; T461-Y465 WeakPolarHBondContact O-CD2 3.5Å; T461-Y465 PolarHBondContact O-N 3.15Å; L462-Y465 PolarHBondContact O-N 3.25Å; I463-Y465 PolarHBondContact O-N 3.08Å; Y465-A469 WeakPolarHBondContact O-CB 3.44Å; Y465-A469 PolarHBondContact O-N 3.18Å
466V98.7Very high97.2Very high0 Ų061.1 Ų61.10%029%0.292CS..Hα-helixtrans-65.5-46.8175167.20000110.9I22 L44 L143 I145 V166 L252 L462 I463 F468 A469 A470I22-V466 HydrophobicContact CD1-CG1 3.59Å; L44-V466 HydrophobicContact CD1-CG1 4.04Å; L44-V466 HydrophobicContact CD1-CG2 4.37Å; L44-V466 HydrophobicContact CD2-CB 3.84Å; L44-V466 HydrophobicContact CD2-CG1 3.63Å; L44-V466 HydrophobicContact CD2-CG2 4.16Å; L143-V466 HydrophobicContact CD2-CB 4.47Å; L143-V466 HydrophobicContact CD2-CG1 3.7Å; I145-V466 HydrophobicContact CD1-CG1 4.2Å; I145-V466 HydrophobicContact CD1-CG2 4.13Å; V166-V466 HydrophobicContact CG2-CG2 4.3Å; L252-V466 HydrophobicContact CD1-CG2 4.07Å; L462-V466 HydrophobicContact CD1-CG2 3.66Å; L462-V466 HydrophobicContact CG-CG2 4.43Å; L462-V466 VanDerWaalsContact O-CB 3.28Å; L462-V466 WeakPolarHBondContact O-CB 3.46Å; L462-V466 VanDerWaalsContact O-CG2 3.22Å; L462-V466 WeakPolarHBondContact O-CG2 3.44Å; L462-V466 PolarHBondContact O-N 2.95Å; I463-V466 PolarHBondContact O-N 3.41Å; V466-F468 VanDerWaalsContact C-N 3.34Å; V466-F468 PolarHBondContact O-N 3.49Å; V466-A469 WeakPolarHBondContact O-CB 3.47Å; V466-A469 PolarHBondContact O-N 3.1Å; V466-A470 WeakPolarHBondContact O-CB 3.39Å; V466-A470 PolarHBondContact O-N 3.18Å
467E98.3Very high97.4Very high56 Ų5662 Ų6226%0.26230%0.303SS..Hα-helixtrans-65.7-37177.7-69.7179.5173.300112Y20 N49 I463 A470 R471Y20-E467 HydrophobicContact CD2-CB 4.17Å; Y20-E467 HydrophobicContact CD2-CG 3.9Å; Y20-E467 HydrophobicContact CE2-CB 3.86Å; Y20-E467 HydrophobicContact CE2-CG 4Å; N49-E467 PolarHBondContact ND2-OE1 2.92Å; I463-E467 HydrophobicContact CG2-CG 4.25Å; I463-E467 WeakPolarHBondContact CG2-OE1 3.41Å; I463-E467 WeakPolarHBondContact O-CB 3.27Å; I463-E467 VanDerWaalsContact O-CG 3.3Å; I463-E467 WeakPolarHBondContact O-CG 2.98Å; I463-E467 PolarHBondContact O-N 3.5Å; E467-A470 PolarHBondContact O-N 2.95Å; E467-R471 VanDerWaalsContact O-CB 3.29Å; E467-R471 WeakPolarHBondContact O-CB 3.39Å; E467-R471 PolarHBondContact O-N 3.04Å
468F98.1Very high97.5Very high93 Ų9361 Ų6141%0.40830%0.297SS..Hα-helixtrans-61.1-46.6172.1-169.6-80.2000111.3F250 K464 V466 R471 F472 L475F250-F468 HydrophobicContact CE2-CB 4.45Å; F250-F468 AromaticContact CE2-CD1 3.89Å; F250-F468 HydrophobicContact CE2-CD1 3.89Å; F250-F468 AromaticContact CZ-CD1 3.89Å; F250-F468 HydrophobicContact CZ-CD1 3.89Å; F250-F468 HydrophobicContact CZ-CE1 4.34Å; K464-F468 WeakPolarHBondContact O-CB 3.08Å; K464-F468 PolarHBondContact O-N 3.36Å; V466-F468 VanDerWaalsContact C-N 3.34Å; V466-F468 PolarHBondContact O-N 3.49Å; F468-R471 PolarHBondContact O-N 3.07Å; F468-F472 AromaticContact CD1-CD2 3.68Å; F468-F472 HydrophobicContact CD1-CD2 3.68Å; F468-F472 HydrophobicContact CD1-CE2 4.45Å; F468-F472 AromaticContact CD2-CD2 3.71Å; F468-F472 HydrophobicContact CD2-CD2 3.71Å; F468-F472 AromaticContact CD2-CE2 3.63Å; F468-F472 HydrophobicContact CD2-CE2 3.63Å; F468-F472 HydrophobicContact CE1-CB 4.25Å; F468-F472 AromaticContact CE1-CD2 3.57Å; F468-F472 HydrophobicContact CE1-CD2 3.57Å; F468-F472 HydrophobicContact CE1-CE2 4.3Å; F468-F472 HydrophobicContact CE1-CG 4.19Å; F468-F472 AromaticContact CE2-CD2 3.6Å; F468-F472 HydrophobicContact CE2-CD2 3.6Å; F468-F472 AromaticContact CE2-CE2 3.46Å; F468-F472 HydrophobicContact CE2-CE2 3.46Å; F468-F472 VanDerWaalsContact CE2-CE2 3.46Å; F468-F472 HydrophobicContact CE2-CZ 4.47Å; F468-F472 AromaticContact CG-CD2 3.75Å; F468-F472 HydrophobicContact CG-CD2 3.75Å; F468-F472 HydrophobicContact CG-CE2 4.14Å; F468-F472 AromaticContact CZ-CD2 3.53Å; F468-F472 HydrophobicContact CZ-CD2 3.53Å; F468-F472 AromaticContact CZ-CE2 3.82Å; F468-F472 HydrophobicContact CZ-CE2 3.82Å; F468-F472 HydrophobicContact CZ-CG 4.28Å; F468-F472 VanDerWaalsContact O-CD2 3.29Å; F468-F472 WeakPolarHBondContact O-CD2 3.4Å; F468-F472 PolarHBondContact O-N 2.94Å; F468-L475 HydrophobicContact CD1-CD1 4.29Å; F468-L475 HydrophobicContact CE1-CD1 3.95Å; F468-L475 HydrophobicContact CE1-CD2 4.11Å
469A98.5Very high97.4Very high0 Ų062.3 Ų62.30%030%0.302CS..Hα-helixtrans-62.9-41.9176.700000112.1L143 V166 F250 Y465 V466 R471 G473L143-A469 HydrophobicContact CD1-CB 3.76Å; L143-A469 HydrophobicContact CD2-CB 4.13Å; V166-A469 HydrophobicContact CG1-CB 3.63Å; F250-A469 HydrophobicContact CD2-CB 4.17Å; F250-A469 HydrophobicContact CE2-CB 4.3Å; Y465-A469 WeakPolarHBondContact O-CB 3.44Å; Y465-A469 PolarHBondContact O-N 3.18Å; V466-A469 WeakPolarHBondContact O-CB 3.47Å; V466-A469 PolarHBondContact O-N 3.1Å; A469-R471 VanDerWaalsContact C-N 3.31Å; A469-R471 PolarHBondContact O-N 3.49Å; A469-G473 WeakPolarHBondContact O-CA 3.38Å; A469-G473 PolarHBondContact O-N 2.73Å
470A98.2Very high97.3Very high3 Ų359.5 Ų59.53%0.02529%0.292CS..Hα-helixtrans-63.2-38.6176.400000111.7Y20 D142 L143 V466 E467Y20-A470 HydrophobicContact CD1-CB 3.55Å; Y20-A470 HydrophobicContact CD2-CB 4.15Å; Y20-A470 HydrophobicContact CE1-CB 3.99Å; Y20-A470 HydrophobicContact CG-CB 3.64Å; D142-A470 HydrophobicContact CB-CB 4.27Å; L143-A470 HydrophobicContact CB-CB 3.94Å; L143-A470 HydrophobicContact CD2-CB 4.43Å; V466-A470 WeakPolarHBondContact O-CB 3.39Å; V466-A470 PolarHBondContact O-N 3.18Å; E467-A470 PolarHBondContact O-N 2.95Å
471R97.5Very high97.1Very high160 Ų16063 Ų6360%0.60430%0.303SS*.Hα-helixtrans-70.8-49.1179.2-172.4171177.7176.30.1113.4Y20 E467 F468 A469Y20-R471 HydrophobicContact CE1-CB 4.45Å; Y20-R471 WeakPolarHBondContact OH-CB 3.45Å; E467-R471 VanDerWaalsContact O-CB 3.29Å; E467-R471 WeakPolarHBondContact O-CB 3.39Å; E467-R471 PolarHBondContact O-N 3.04Å; F468-R471 PolarHBondContact O-N 3.07Å; A469-R471 VanDerWaalsContact C-N 3.31Å; A469-R471 PolarHBondContact O-N 3.49Å
472F97.8Very high96.9Very high103 Ų10362.6 Ų62.645%0.45230%0.302SS..Hα-helixtrans-101-19-168.5-63.3-69.1000113.4F468 L475F468-F472 AromaticContact CD1-CD2 3.68Å; F468-F472 HydrophobicContact CD1-CD2 3.68Å; F468-F472 HydrophobicContact CD1-CE2 4.45Å; F468-F472 AromaticContact CD2-CD2 3.71Å; F468-F472 HydrophobicContact CD2-CD2 3.71Å; F468-F472 AromaticContact CD2-CE2 3.63Å; F468-F472 HydrophobicContact CD2-CE2 3.63Å; F468-F472 HydrophobicContact CE1-CB 4.25Å; F468-F472 AromaticContact CE1-CD2 3.57Å; F468-F472 HydrophobicContact CE1-CD2 3.57Å; F468-F472 HydrophobicContact CE1-CE2 4.3Å; F468-F472 HydrophobicContact CE1-CG 4.19Å; F468-F472 AromaticContact CE2-CD2 3.6Å; F468-F472 HydrophobicContact CE2-CD2 3.6Å; F468-F472 AromaticContact CE2-CE2 3.46Å; F468-F472 HydrophobicContact CE2-CE2 3.46Å; F468-F472 VanDerWaalsContact CE2-CE2 3.46Å; F468-F472 HydrophobicContact CE2-CZ 4.47Å; F468-F472 AromaticContact CG-CD2 3.75Å; F468-F472 HydrophobicContact CG-CD2 3.75Å; F468-F472 HydrophobicContact CG-CE2 4.14Å; F468-F472 AromaticContact CZ-CD2 3.53Å; F468-F472 HydrophobicContact CZ-CD2 3.53Å; F468-F472 AromaticContact CZ-CE2 3.82Å; F468-F472 HydrophobicContact CZ-CE2 3.82Å; F468-F472 HydrophobicContact CZ-CG 4.28Å; F468-F472 VanDerWaalsContact O-CD2 3.29Å; F468-F472 WeakPolarHBondContact O-CD2 3.4Å; F468-F472 PolarHBondContact O-N 2.94Å; F472-L475 HydrophobicContact CB-CD2 4.4Å
473G97.9Very high96.6Very high2 Ų265.9 Ų65.92%0.02132%0.315CS..  trans73.7-149.9-177.800000112.8A164 S249 A469A164-G473 VanDerWaalsContact CB-CA 3.46Å; S249-G473 PolarHBondContact OG-O 3.17Å; A469-G473 WeakPolarHBondContact O-CA 3.38Å; A469-G473 PolarHBondContact O-N 2.73Å
474K97.4Very high96.5Very high81 Ų8169.3 Ų69.335%0.35233%0.33SS..  trans-57142.4-179.4-57179.2-174.8-175.80111.4R163 E247 P476R163-K474 WeakPolarHBondContact O-CE 3.45Å; E247-K474 HydrophobicContact CB-CD 4.21Å; E247-K474 WeakPolarHBondContact OE2-CE 3.44Å; E247-K474 IonicContact OE2-NZ 3.91Å; E247-K474 PolarHBondContact OE2-NZ 2.57Å; K474-P476 VanDerWaalsContact O-CD 3.26Å; K474-P476 WeakPolarHBondContact O-CD 3.48Å
475L97.3Very high96.3Very high27 Ų2766.7 Ų66.714%0.14132%0.319CS..  trans-117.778.2-178.5-59178.5000110.6F250 F468 F472 S477 L478F250-L475 HydrophobicContact CE1-CD1 3.9Å; F250-L475 HydrophobicContact CE2-CD1 3.89Å; F250-L475 HydrophobicContact CZ-CD1 3.42Å; F250-L475 VanDerWaalsContact CZ-CD1 3.42Å; F468-L475 HydrophobicContact CD1-CD1 4.29Å; F468-L475 HydrophobicContact CE1-CD1 3.95Å; F468-L475 HydrophobicContact CE1-CD2 4.11Å; F472-L475 HydrophobicContact CB-CD2 4.4Å; L475-S477 PolarHBondContact O-N 2.58Å; L475-S477 VanDerWaalsContact O-N 3.16Å; L475-L478 HydrophobicContact CB-CB 4.37Å; L475-L478 HydrophobicContact CB-CD1 4.23Å; L475-L478 HydrophobicContact CB-CG 4.25Å; L475-L478 HydrophobicContact CD1-CD1 3.82Å; L475-L478 PolarHBondContact O-N 2.78Å
476P95.8Very high96.1Very high109 Ų10965.2 Ų65.271%0.70832%0.321SS*.G310 helixtrans-62.3-22.1179.526.3-34.9000112.8K474 L478 D479K474-P476 VanDerWaalsContact O-CD 3.26Å; K474-P476 WeakPolarHBondContact O-CD 3.48Å; P476-L478 PolarHBondContact O-N 3.02Å; P476-D479 WeakPolarHBondContact O-CB 3.45Å; P476-D479 PolarHBondContact O-N 2.84Å; P476-D479 VanDerWaalsContact O-N 3.11Å
477S95.2Very high95.8Very high108 Ų10872.3 Ų72.376%0.75535%0.349SS*.G310 helixtrans-65.3-15.6172.357.70000114L475L475-S477 PolarHBondContact O-N 2.58Å; L475-S477 VanDerWaalsContact O-N 3.16Å
478L95.4Very high95.7Very high47 Ų4774.1 Ų74.125%0.24636%0.36CS..G310 helixtrans-105.69.8174.7-61.3-176000112.4F250 K268 L475 P476 N480F250-L478 HydrophobicContact CD1-CD1 4.36Å; F250-L478 HydrophobicContact CE1-CD1 3.76Å; K268-L478 HydrophobicContact CB-CB 4.38Å; K268-L478 HydrophobicContact CG-CB 4.49Å; L475-L478 HydrophobicContact CB-CB 4.37Å; L475-L478 HydrophobicContact CB-CD1 4.23Å; L475-L478 HydrophobicContact CB-CG 4.25Å; L475-L478 HydrophobicContact CD1-CD1 3.82Å; L475-L478 PolarHBondContact O-N 2.78Å; P476-L478 PolarHBondContact O-N 3.02Å; L478-N480 PolarHBondContact O-N 2.94Å
479D94.7Very high95.6Very high56 Ų5673.8 Ų73.830%0.29936%0.36SS..SBendtrans-78115.2171.2-17230.7000109.7P476 Y481 R483 H484P476-D479 WeakPolarHBondContact O-CB 3.45Å; P476-D479 PolarHBondContact O-N 2.84Å; P476-D479 VanDerWaalsContact O-N 3.11Å; D479-Y481 PolarHBondContact O-N 2.81Å; D479-Y481 VanDerWaalsContact O-N 3.17Å; D479-R483 WeakPolarHBondContact OD1-CD 3.49Å; D479-R483 IonicContact OD1-NE 3.55Å; D479-H484 IonicContact OD2-CD2 2.94Å; D479-H484 IonicContact OD2-CE1 3.02Å; D479-H484 IonicContact OD2-NE2 3.23Å; D479-H484 PolarHBondContact OD2-NE2 3.3Å
480N93Very high95.4Very high46 Ų4678 Ų7825%0.24638%0.376CS..  trans-68.9114.5-178.9176.421.8000110G182 F266 L478 G482 R483G182-N480 PolarHBondContact O-ND2 3.26Å; F266-N480 HydrophobicContact CD1-CB 4.44Å; F266-N480 HydrophobicContact CE1-CB 3.96Å; F266-N480 HydrophobicContact CZ-CB 4.15Å; L478-N480 PolarHBondContact O-N 2.94Å; N480-G482 PolarHBondContact O-N 3.35Å; N480-G482 VanDerWaalsContact O-N 3.08Å; N480-G482 PolarHBondContact OD1-N 3.42Å; N480-G482 VanDerWaalsContact OD1-N 3.16Å; N480-R483 WeakPolarHBondContact O-CG 3.27Å; N480-R483 PolarHBondContact O-N 3.35Å; N480-R483 VanDerWaalsContact O-N 3.16Å
481Y93.3Very high95.3Very high166 Ų16682.5 Ų82.565%0.65140%0.395SS*.G310 helixtrans-59.3-25.4-178.9-165.9-97.9000113.9D479 R483 H484 Q485D479-Y481 PolarHBondContact O-N 2.81Å; D479-Y481 VanDerWaalsContact O-N 3.17Å; Y481-R483 PolarHBondContact O-N 2.79Å; Y481-H484 PolarHBondContact O-N 3.43Å; Y481-Q485 HydrophobicContact CD1-CG 4.18Å; Y481-Q485 HydrophobicContact CE1-CG 4.17Å
482G93.4Very high95.3Very high11 Ų1181.3 Ų81.311%0.11340%0.395CS..G310 helixtrans-55.8-25.9177.700000114N480 H484 Q485N480-G482 PolarHBondContact O-N 3.35Å; N480-G482 VanDerWaalsContact O-N 3.08Å; N480-G482 PolarHBondContact OD1-N 3.42Å; N480-G482 VanDerWaalsContact OD1-N 3.16Å; G482-H484 PolarHBondContact O-N 3.36Å; G482-Q485 PolarHBondContact O-N 3.49Å
483R93.6Very high95.3Very high68 Ų6880 Ų8026%0.25739%0.392SS..G310 helixtrans-65.3-24.3175.377.6-177.7-75.4104.419.5114.1V180 I181 P246 D479 N480 Y481V180-R483 PolarHBondContact O-NH1 2.84Å; V180-R483 PolarHBondContact O-NH2 3.35Å; I181-R483 VanDerWaalsContact C-NH1 3.29Å; I181-R483 PolarHBondContact O-NH1 2.94Å; P246-R483 VanDerWaalsContact CB-NH1 3.32Å; P246-R483 VanDerWaalsContact CG-NH1 3.33Å; D479-R483 WeakPolarHBondContact OD1-CD 3.49Å; D479-R483 IonicContact OD1-NE 3.55Å; N480-R483 WeakPolarHBondContact O-CG 3.27Å; N480-R483 PolarHBondContact O-N 3.35Å; N480-R483 VanDerWaalsContact O-N 3.16Å; Y481-R483 PolarHBondContact O-N 2.79Å
484H95Very high95.3Very high107 Ų10782.8 Ų82.850%0.49541%0.407SS..G310 helixtrans-93.4-6.8-176.8-59-62.6000111D479 Y481 G482D479-H484 IonicContact OD2-CD2 2.94Å; D479-H484 IonicContact OD2-CE1 3.02Å; D479-H484 IonicContact OD2-NE2 3.23Å; D479-H484 PolarHBondContact OD2-NE2 3.3Å; Y481-H484 PolarHBondContact O-N 3.43Å; G482-H484 PolarHBondContact O-N 3.36Å
485Q95.1Very high95.3Very high72 Ų7282.5 Ų82.534%0.33641%0.408SS..SBendtrans-87.5146.7177.1-63.2-172.7-67.300110.7Y481 G482 E489Y481-Q485 HydrophobicContact CD1-CG 4.18Å; Y481-Q485 HydrophobicContact CE1-CG 4.17Å; G482-Q485 PolarHBondContact O-N 3.49Å; Q485-E489 WeakPolarHBondContact CA-OE2 3.39Å; Q485-E489 HydrophobicContact CB-CB 4.13Å
486S94.9Very high95.4Very high54 Ų5486 Ų8638%0.37843%0.426SS..  trans-68.3159.9166.767.60000110.9I488 E489 Y490S486-I488 PolarHBondContact O-N 3Å; S486-I488 VanDerWaalsContact O-N 3.14Å; S486-E489 PolarHBondContact N-OE2 3Å; S486-E489 PolarHBondContact O-N 3.07Å; S486-E489 VanDerWaalsContact O-N 3.15Å; S486-E489 WeakPolarHBondContact OG-CG 3.31Å; S486-E489 PolarHBondContact OG-N 3.17Å; S486-E489 PolarHBondContact OG-OE2 3.15Å; S486-Y490 WeakPolarHBondContact O-CB 3.33Å; S486-Y490 PolarHBondContact O-N 3.37Å
487Y91.4Very high95.5Very high150 Ų15083.3 Ų83.359%0.58841%0.412SS*.Hα-helixtrans-55-32172.6-173.8-87.9000112.3F491 L493Y487-F491 HydrophobicContact CD1-CD2 4.08Å; Y487-F491 AromaticContact CD2-CD2 3.75Å; Y487-F491 HydrophobicContact CD2-CD2 3.75Å; Y487-F491 AromaticContact CD2-CE2 3.62Å; Y487-F491 HydrophobicContact CD2-CE2 3.62Å; Y487-F491 AromaticContact CE1-CD2 3.84Å; Y487-F491 HydrophobicContact CE1-CD2 3.84Å; Y487-F491 HydrophobicContact CE1-CE2 4.38Å; Y487-F491 AromaticContact CE2-CD2 3.51Å; Y487-F491 HydrophobicContact CE2-CD2 3.51Å; Y487-F491 AromaticContact CE2-CE2 3.21Å; Y487-F491 HydrophobicContact CE2-CE2 3.21Å; Y487-F491 HydrophobicContact CE2-CZ 4.26Å; Y487-F491 HydrophobicContact CG-CD2 4.02Å; Y487-F491 HydrophobicContact CG-CE2 4.36Å; Y487-F491 AromaticContact CZ-CD2 3.53Å; Y487-F491 AromaticContact CZ-CE2 3.63Å; Y487-F491 WeakPolarHBondContact O-CD2 3.22Å; Y487-F491 PolarHBondContact O-N 2.91Å; Y487-L493 HydrophobicContact CD1-CD1 3.92Å; Y487-L493 HydrophobicContact CE1-CD1 3.86Å
488I96.5Very high95.6Very high94 Ų9482.9 Ų82.948%0.48240%0.401SS..Hα-helixtrans-65.8-49.3178.9-63.2175.2000110.5S486 F492 L493 D494S486-I488 PolarHBondContact O-N 3Å; S486-I488 VanDerWaalsContact O-N 3.14Å; I488-F492 PolarHBondContact O-N 3.25Å; I488-L493 HydrophobicContact CG2-CB 4.1Å; I488-L493 PolarHBondContact O-N 2.76Å; I488-D494 HydrophobicContact CG2-CB 3.84Å
489E96.7Very high95.7Very high86 Ų8685.3 Ų85.340%0.40241%0.414SS..Hα-helixtrans-69.4-44.9-179.8-68.2163158.200111.6Q485 S486 F491 F492Q485-E489 WeakPolarHBondContact CA-OE2 3.39Å; Q485-E489 HydrophobicContact CB-CB 4.13Å; S486-E489 PolarHBondContact N-OE2 3Å; S486-E489 PolarHBondContact O-N 3.07Å; S486-E489 VanDerWaalsContact O-N 3.15Å; S486-E489 WeakPolarHBondContact OG-CG 3.31Å; S486-E489 PolarHBondContact OG-N 3.17Å; S486-E489 PolarHBondContact OG-OE2 3.15Å; E489-F491 VanDerWaalsContact C-N 3.28Å; E489-F491 PolarHBondContact O-N 3.1Å; E489-F492 PolarHBondContact O-N 3.3Å; E489-F492 VanDerWaalsContact O-N 3.08Å
490Y94.2Very high95.9Very high88 Ų8884.9 Ų84.935%0.34542%0.418SS..Hα-helixtrans-60-38-176.5-174.6-88.8000112.5S486S486-Y490 WeakPolarHBondContact O-CB 3.33Å; S486-Y490 PolarHBondContact O-N 3.37Å
491F94.5Very high96.2Very high98 Ų9887.4 Ų87.443%0.4343%0.434SS..THydrogen-bonded Turntrans-9811.2178.1-70.4-71.4000113.9Y487 E489 L493Y487-F491 HydrophobicContact CD1-CD2 4.08Å; Y487-F491 AromaticContact CD2-CD2 3.75Å; Y487-F491 HydrophobicContact CD2-CD2 3.75Å; Y487-F491 AromaticContact CD2-CE2 3.62Å; Y487-F491 HydrophobicContact CD2-CE2 3.62Å; Y487-F491 AromaticContact CE1-CD2 3.84Å; Y487-F491 HydrophobicContact CE1-CD2 3.84Å; Y487-F491 HydrophobicContact CE1-CE2 4.38Å; Y487-F491 AromaticContact CE2-CD2 3.51Å; Y487-F491 HydrophobicContact CE2-CD2 3.51Å; Y487-F491 AromaticContact CE2-CE2 3.21Å; Y487-F491 HydrophobicContact CE2-CE2 3.21Å; Y487-F491 HydrophobicContact CE2-CZ 4.26Å; Y487-F491 HydrophobicContact CG-CD2 4.02Å; Y487-F491 HydrophobicContact CG-CE2 4.36Å; Y487-F491 AromaticContact CZ-CD2 3.53Å; Y487-F491 AromaticContact CZ-CE2 3.63Å; Y487-F491 WeakPolarHBondContact O-CD2 3.22Å; Y487-F491 PolarHBondContact O-N 2.91Å; E489-F491 VanDerWaalsContact C-N 3.28Å; E489-F491 PolarHBondContact O-N 3.1Å; F491-L493 HydrophobicContact CB-CD2 4.32Å; F491-L493 HydrophobicContact CB-CG 4.08Å; F491-L493 PolarHBondContact O-N 3.35Å; F491-L493 VanDerWaalsContact O-N 3.16Å
492F97.5Very high96.4Very high134 Ų13483.9 Ų83.959%0.58843%0.426SS*.THydrogen-bonded Turntrans5430.9-179.4-64.8-65.6000113.9I488 E489 D494 I495 I496I488-F492 PolarHBondContact O-N 3.25Å; E489-F492 PolarHBondContact O-N 3.3Å; E489-F492 VanDerWaalsContact O-N 3.08Å; F492-D494 VanDerWaalsContact C-OD1 3.24Å; F492-D494 WeakPolarHBondContact CA-OD1 3.13Å; F492-D494 PolarHBondContact O-N 2.04Å; F492-I495 HydrophobicContact CB-CB 4.14Å; F492-I495 HydrophobicContact CB-CG1 4.27Å; F492-I495 HydrophobicContact CD1-CB 4.47Å; F492-I495 HydrophobicContact CD1-CG1 3.77Å; F492-I495 HydrophobicContact CG-CG1 4.48Å; F492-I495 PolarHBondContact O-N 3.42Å; F492-I495 VanDerWaalsContact O-N 3.17Å; F492-I496 WeakPolarHBondContact O-CB 3.42Å; F492-I496 VanDerWaalsContact O-CG1 3.26Å; F492-I496 WeakPolarHBondContact O-CG1 2.99Å; F492-I496 PolarHBondContact O-N 3.34Å
493L98Very high96.6Very high77 Ų7786.6 Ų86.640%0.40344%0.443SS..Hα-helixtrans-66-32-179.4-61.7-176.4000111.5Y487 I488 F491 I496 A497Y487-L493 HydrophobicContact CD1-CD1 3.92Å; Y487-L493 HydrophobicContact CE1-CD1 3.86Å; I488-L493 HydrophobicContact CG2-CB 4.1Å; I488-L493 PolarHBondContact O-N 2.76Å; F491-L493 HydrophobicContact CB-CD2 4.32Å; F491-L493 HydrophobicContact CB-CG 4.08Å; F491-L493 PolarHBondContact O-N 3.35Å; F491-L493 VanDerWaalsContact O-N 3.16Å; L493-I496 HydrophobicContact CD2-CD1 4.37Å; L493-A497 VanDerWaalsContact O-CB 3.26Å; L493-A497 WeakPolarHBondContact O-CB 3.47Å; L493-A497 PolarHBondContact O-N 2.95Å
494D97.7Very high96.8Very high60 Ų6089 Ų8932%0.32146%0.461SS..Hα-helixtrans-60.7-48.4168.956.6-17.7000112.1I488 F492 A497 I498I488-D494 HydrophobicContact CG2-CB 3.84Å; F492-D494 VanDerWaalsContact C-OD1 3.24Å; F492-D494 WeakPolarHBondContact CA-OD1 3.13Å; F492-D494 PolarHBondContact O-N 2.04Å; D494-A497 PolarHBondContact O-N 3.47Å; D494-I498 WeakPolarHBondContact O-CG1 3.46Å; D494-I498 PolarHBondContact O-N 3.06Å
495I98.1Very high96.9Very high75 Ų7590 Ų9039%0.38546%0.464SS..Hα-helixtrans-66.5-43.8178.1-55.8-55.8000110.9F492 A497 I498 L499F492-I495 HydrophobicContact CB-CB 4.14Å; F492-I495 HydrophobicContact CB-CG1 4.27Å; F492-I495 HydrophobicContact CD1-CB 4.47Å; F492-I495 HydrophobicContact CD1-CG1 3.77Å; F492-I495 HydrophobicContact CG-CG1 4.48Å; F492-I495 PolarHBondContact O-N 3.42Å; F492-I495 VanDerWaalsContact O-N 3.17Å; I495-A497 VanDerWaalsContact C-N 3.29Å; I495-A497 PolarHBondContact O-N 3.07Å; I495-I498 PolarHBondContact O-N 2.94Å; I495-L499 HydrophobicContact CG2-CD1 4.18Å; I495-L499 HydrophobicContact CG2-CG 4.42Å; I495-L499 WeakPolarHBondContact O-CG 3.47Å; I495-L499 PolarHBondContact O-N 2.83Å
496I98.4Very high97.1Very high101 Ų10189.3 Ų89.352%0.51847%0.467SS..Hα-helixtrans-59.3-43.5175.8-69.4165.8000110F492 L493 L499 A500F492-I496 WeakPolarHBondContact O-CB 3.42Å; F492-I496 VanDerWaalsContact O-CG1 3.26Å; F492-I496 WeakPolarHBondContact O-CG1 2.99Å; F492-I496 PolarHBondContact O-N 3.34Å; L493-I496 HydrophobicContact CD2-CD1 4.37Å; I496-L499 PolarHBondContact O-N 3.36Å; I496-A500 VanDerWaalsContact O-CB 3.32Å; I496-A500 WeakPolarHBondContact O-CB 3.29Å; I496-A500 PolarHBondContact O-N 3.37Å
497A98.1Very high97.2Very high51 Ų5192.3 Ų92.342%0.42148%0.478SS..Hα-helixtrans-62.1-44.1176.400000112.1L493 D494 I495 A500 V501L493-A497 VanDerWaalsContact O-CB 3.26Å; L493-A497 WeakPolarHBondContact O-CB 3.47Å; L493-A497 PolarHBondContact O-N 2.95Å; D494-A497 PolarHBondContact O-N 3.47Å; I495-A497 VanDerWaalsContact C-N 3.29Å; I495-A497 PolarHBondContact O-N 3.07Å; A497-A500 PolarHBondContact O-N 3.03Å; A497-V501 WeakPolarHBondContact O-CG2 2.97Å; A497-V501 PolarHBondContact O-N 2.91Å
498I98.3Very high97.5Very high99 Ų9991.6 Ų91.651%0.50848%0.475SS..Hα-helixtrans-59.6-47.6175.9-69.5164.7000111.1D494 I495 A500 V501 I502D494-I498 WeakPolarHBondContact O-CG1 3.46Å; D494-I498 PolarHBondContact O-N 3.06Å; I495-I498 PolarHBondContact O-N 2.94Å; I498-A500 PolarHBondContact O-N 3.5Å; I498-V501 PolarHBondContact O-N 2.61Å; I498-I502 HydrophobicContact CG2-CD1 3.87Å; I498-I502 WeakPolarHBondContact O-CG1 3.26Å; I498-I502 PolarHBondContact O-N 3.09Å
499L98.2Very high97.5Very high99 Ų9990.2 Ų90.252%0.51847%0.468SS..Hα-helixtrans-65-37.9179.3-68.8177.1000112.5I495 I496 I502 S503I495-L499 HydrophobicContact CG2-CD1 4.18Å; I495-L499 HydrophobicContact CG2-CG 4.42Å; I495-L499 WeakPolarHBondContact O-CG 3.47Å; I495-L499 PolarHBondContact O-N 2.83Å; I496-L499 PolarHBondContact O-N 3.36Å; L499-I502 PolarHBondContact O-N 3.01Å; L499-S503 WeakPolarHBondContact O-CB 3.19Å; L499-S503 PolarHBondContact O-N 3.4Å; L499-S503 PolarHBondContact O-OG 2.85Å
500A98.2Very high97.5Very high47 Ų4789.5 Ų89.539%0.38847%0.472SS..Hα-helixtrans-62.8-44.4174.700000111.3I496 A497 I498 S503 L504I496-A500 VanDerWaalsContact O-CB 3.32Å; I496-A500 WeakPolarHBondContact O-CB 3.29Å; I496-A500 PolarHBondContact O-N 3.37Å; A497-A500 PolarHBondContact O-N 3.03Å; I498-A500 PolarHBondContact O-N 3.5Å; A500-S503 PolarHBondContact O-N 3.34Å; A500-L504 WeakPolarHBondContact O-CB 3.38Å; A500-L504 VanDerWaalsContact O-CG 3.27Å; A500-L504 WeakPolarHBondContact O-CG 3.42Å; A500-L504 PolarHBondContact O-N 3.39Å
501V98.2Very high97.6Very high98 Ų9891.8 Ų91.859%0.59448%0.481SS*.Hα-helixtrans-62-45.5176.6171.20000111.5A497 I498 S503 L504 F505A497-V501 WeakPolarHBondContact O-CG2 2.97Å; A497-V501 PolarHBondContact O-N 2.91Å; I498-V501 PolarHBondContact O-N 2.61Å; V501-S503 VanDerWaalsContact C-N 3.33Å; V501-S503 PolarHBondContact O-N 3.45Å; V501-L504 PolarHBondContact O-N 3.03Å; V501-F505 WeakPolarHBondContact O-CB 3.38Å; V501-F505 PolarHBondContact O-N 3.43Å
502I98.2Very high97.7Very high92 Ų9290.5 Ų90.547%0.47248%0.479SS..Hα-helixtrans-62-42178-69.6164.3000111.3I498 L499 F505 S506I498-I502 HydrophobicContact CG2-CD1 3.87Å; I498-I502 WeakPolarHBondContact O-CG1 3.26Å; I498-I502 PolarHBondContact O-N 3.09Å; L499-I502 PolarHBondContact O-N 3.01Å; I502-F505 PolarHBondContact O-N 3.47Å; I502-S506 WeakPolarHBondContact O-CB 3.31Å; I502-S506 PolarHBondContact O-N 3.15Å; I502-S506 PolarHBondContact O-OG 2.92Å
503S97.8Very high97.6Very high68 Ų6888.9 Ų88.948%0.47648%0.475SS..Hα-helixtrans-67.1-44.6179.4-67.10000111.5L499 A500 V501 F505 S506 L507L499-S503 WeakPolarHBondContact O-CB 3.19Å; L499-S503 PolarHBondContact O-N 3.4Å; L499-S503 PolarHBondContact O-OG 2.85Å; A500-S503 PolarHBondContact O-N 3.34Å; V501-S503 VanDerWaalsContact C-N 3.33Å; V501-S503 PolarHBondContact O-N 3.45Å; S503-F505 PolarHBondContact O-N 3.41Å; S503-S506 PolarHBondContact O-N 2.96Å; S503-L507 WeakPolarHBondContact O-CB 3.47Å; S503-L507 VanDerWaalsContact O-CG 3.29Å; S503-L507 WeakPolarHBondContact O-CG 3.35Å; S503-L507 PolarHBondContact O-N 2.96Å
504L98Very high97.5Very high119 Ų11989.9 Ų89.962%0.62348%0.48SS*.Hα-helixtrans-62.4-41.1174.7-71.7172.4000111.9A500 V501 L507 Y508A500-L504 WeakPolarHBondContact O-CB 3.38Å; A500-L504 VanDerWaalsContact O-CG 3.27Å; A500-L504 WeakPolarHBondContact O-CG 3.42Å; A500-L504 PolarHBondContact O-N 3.39Å; V501-L504 PolarHBondContact O-N 3.03Å; L504-L507 PolarHBondContact O-N 2.86Å; L504-Y508 WeakPolarHBondContact O-CB 3.25Å; L504-Y508 PolarHBondContact O-N 2.94Å
505F97.9Very high97.3Very high128 Ų12892.8 Ų92.856%0.56149%0.487SS*.Hα-helixtrans-64-43.8175.7-175.3-103000111.9V501 I502 S503 Y508 I509V501-F505 WeakPolarHBondContact O-CB 3.38Å; V501-F505 PolarHBondContact O-N 3.43Å; I502-F505 PolarHBondContact O-N 3.47Å; S503-F505 PolarHBondContact O-N 3.41Å; F505-Y508 WeakPolarHBondContact O-CB 3.22Å; F505-Y508 PolarHBondContact O-N 3.16Å; F505-I509 HydrophobicContact CD1-CG1 4.21Å; F505-I509 HydrophobicContact CE1-CD1 4.34Å; F505-I509 HydrophobicContact CE1-CG1 3.83Å; F505-I509 HydrophobicContact CE2-CD1 4.4Å; F505-I509 HydrophobicContact CE2-CG1 4.42Å; F505-I509 HydrophobicContact CZ-CD1 3.98Å; F505-I509 HydrophobicContact CZ-CG1 3.95Å; F505-I509 WeakPolarHBondContact O-CG1 3.38Å; F505-I509 PolarHBondContact O-N 3.35Å
506S97.3Very high97.1Very high58 Ų5891.9 Ų91.941%0.40649%0.49SS..Hα-helixtrans-65.2-40.4178.3-57.50000112.2I502 S503 Y508 I509 S510I502-S506 WeakPolarHBondContact O-CB 3.31Å; I502-S506 PolarHBondContact O-N 3.15Å; I502-S506 PolarHBondContact O-OG 2.92Å; S503-S506 PolarHBondContact O-N 2.96Å; S506-Y508 VanDerWaalsContact C-N 3.34Å; S506-I509 PolarHBondContact O-N 3.4Å; S506-S510 WeakPolarHBondContact O-CB 3.41Å; S506-S510 PolarHBondContact O-N 3.42Å; S506-S510 PolarHBondContact O-OG 2.9Å
507L97.5Very high96.8Very high117 Ų11790.4 Ų90.461%0.61349%0.486SS*.Hα-helixtrans-63.4-40.5172.9-73.4172.1000111.4S503 L504 S510 Y511S503-L507 WeakPolarHBondContact O-CB 3.47Å; S503-L507 VanDerWaalsContact O-CG 3.29Å; S503-L507 WeakPolarHBondContact O-CG 3.35Å; S503-L507 PolarHBondContact O-N 2.96Å; L504-L507 PolarHBondContact O-N 2.86Å; L507-S510 PolarHBondContact O-N 2.79Å; L507-Y511 WeakPolarHBondContact O-CB 3.5Å; L507-Y511 PolarHBondContact O-N 2.96Å
508Y97.6Very high96.5Very high135 Ų13591.8 Ų91.853%0.52949%0.485SS..Hα-helixtrans-64.3-45.3176.2178.1-107.1000112.5L504 F505 S506 Y511 I512L504-Y508 WeakPolarHBondContact O-CB 3.25Å; L504-Y508 PolarHBondContact O-N 2.94Å; F505-Y508 WeakPolarHBondContact O-CB 3.22Å; F505-Y508 PolarHBondContact O-N 3.16Å; S506-Y508 VanDerWaalsContact C-N 3.34Å; Y508-Y511 WeakPolarHBondContact O-CB 3.43Å; Y508-Y511 PolarHBondContact O-N 3.01Å; Y508-I512 HydrophobicContact CD1-CD1 3.84Å; Y508-I512 HydrophobicContact CE1-CD1 3.3Å; Y508-I512 HydrophobicContact CE1-CG1 4.34Å; Y508-I512 HydrophobicContact CE2-CD1 4.22Å; Y508-I512 HydrophobicContact CG-CD1 4.5Å; Y508-I512 WeakPolarHBondContact O-CG1 3.49Å; Y508-I512 PolarHBondContact O-N 2.95Å
509I97.4Very high96.1Very high65 Ų6593.3 Ų93.333%0.33349%0.485SS..Hα-helixtrans-62.7-43.7174.8-66.1-62000111.1F505 S506 Y511 I512 I513F505-I509 HydrophobicContact CD1-CG1 4.21Å; F505-I509 HydrophobicContact CE1-CD1 4.34Å; F505-I509 HydrophobicContact CE1-CG1 3.83Å; F505-I509 HydrophobicContact CE2-CD1 4.4Å; F505-I509 HydrophobicContact CE2-CG1 4.42Å; F505-I509 HydrophobicContact CZ-CD1 3.98Å; F505-I509 HydrophobicContact CZ-CG1 3.95Å; F505-I509 WeakPolarHBondContact O-CG1 3.38Å; F505-I509 PolarHBondContact O-N 3.35Å; S506-I509 PolarHBondContact O-N 3.4Å; I509-Y511 VanDerWaalsContact C-N 3.31Å; I509-Y511 PolarHBondContact O-N 3.13Å; I509-I512 PolarHBondContact O-N 3.35Å; I509-I512 VanDerWaalsContact O-N 3.15Å; I509-I513 HydrophobicContact CG2-CD1 3.78Å; I509-I513 HydrophobicContact CG2-CG1 4.41Å; I509-I513 WeakPolarHBondContact O-CG1 3.31Å; I509-I513 PolarHBondContact O-N 3.47Å
510S96.4Very high95.5Very high70 Ų7096.6 Ų96.649%0.4950%0.495SS..Hα-helixtrans-61.3-41176.4-58.90000111.6S506 L507 I513 L514S506-S510 WeakPolarHBondContact O-CB 3.41Å; S506-S510 PolarHBondContact O-N 3.42Å; S506-S510 PolarHBondContact O-OG 2.9Å; L507-S510 PolarHBondContact O-N 2.79Å; S510-I513 PolarHBondContact O-N 3.41Å; S510-L514 VanDerWaalsContact O-CB 3.25Å; S510-L514 WeakPolarHBondContact O-CB 3.26Å; S510-L514 PolarHBondContact O-N 3.44Å
511Y96.8Very high95Very high136 Ų13698.9 Ų98.953%0.53350%0.499SS..Hα-helixtrans-62.1-43173169.1-104.9000112.1L507 Y508 I509 L514 R515L507-Y511 WeakPolarHBondContact O-CB 3.5Å; L507-Y511 PolarHBondContact O-N 2.96Å; Y508-Y511 WeakPolarHBondContact O-CB 3.43Å; Y508-Y511 PolarHBondContact O-N 3.01Å; I509-Y511 VanDerWaalsContact C-N 3.31Å; I509-Y511 PolarHBondContact O-N 3.13Å; Y511-L514 PolarHBondContact O-N 3.13Å; Y511-R515 WeakPolarHBondContact O-CB 3.43Å; Y511-R515 PolarHBondContact O-N 3.3Å
512I96.5Very high94.2Very high72 Ų72101 Ų10137%0.36950%0.501SS..Hα-helixtrans-61-47.8175-71.6171.7000111Y508 I509 R515 A516Y508-I512 HydrophobicContact CD1-CD1 3.84Å; Y508-I512 HydrophobicContact CE1-CD1 3.3Å; Y508-I512 HydrophobicContact CE1-CG1 4.34Å; Y508-I512 HydrophobicContact CE2-CD1 4.22Å; Y508-I512 HydrophobicContact CG-CD1 4.5Å; Y508-I512 WeakPolarHBondContact O-CG1 3.49Å; Y508-I512 PolarHBondContact O-N 2.95Å; I509-I512 PolarHBondContact O-N 3.35Å; I509-I512 VanDerWaalsContact O-N 3.15Å; I512-R515 PolarHBondContact O-N 3.42Å; I512-A516 WeakPolarHBondContact O-CB 3.44Å; I512-A516 PolarHBondContact O-N 3.4Å
513I95.7Very high93Very high99 Ų99103.9 Ų103.951%0.50851%0.51SS..Hα-helixtrans-63.1-47.9179.7-67.5165.9000110.1I509 S510 R515 A516 V517I509-I513 HydrophobicContact CG2-CD1 3.78Å; I509-I513 HydrophobicContact CG2-CG1 4.41Å; I509-I513 WeakPolarHBondContact O-CG1 3.31Å; I509-I513 PolarHBondContact O-N 3.47Å; S510-I513 PolarHBondContact O-N 3.41Å; I513-R515 VanDerWaalsContact C-N 3.32Å; I513-R515 PolarHBondContact O-N 2.89Å; I513-A516 WeakPolarHBondContact O-CB 3.47Å; I513-A516 PolarHBondContact O-N 3.47Å; I513-A516 VanDerWaalsContact O-N 3.09Å; I513-V517 HydrophobicContact CG2-CG2 4.29Å; I513-V517 WeakPolarHBondContact O-CG2 3.46Å; I513-V517 PolarHBondContact O-N 3.29Å
514L95.2Very high91.5Very high99 Ų99103.6 Ų103.652%0.51851%0.508SS..Hα-helixtrans-59.7-44.2177.8-179.962.3000111.1S510 Y511 A516 V517 I518S510-L514 VanDerWaalsContact O-CB 3.25Å; S510-L514 WeakPolarHBondContact O-CB 3.26Å; S510-L514 PolarHBondContact O-N 3.44Å; Y511-L514 PolarHBondContact O-N 3.13Å; L514-A516 VanDerWaalsContact C-N 3.3Å; L514-A516 PolarHBondContact O-N 3.32Å; L514-V517 PolarHBondContact O-N 3.46Å; L514-I518 HydrophobicContact CD1-CD1 3.95Å; L514-I518 HydrophobicContact CD1-CG1 4.15Å; L514-I518 HydrophobicContact CD2-CD1 4.47Å; L514-I518 HydrophobicContact CG-CD1 3.8Å; L514-I518 HydrophobicContact CG-CG1 4.39Å; L514-I518 WeakPolarHBondContact O-CB 3.46Å; L514-I518 VanDerWaalsContact O-CG1 3.25Å; L514-I518 WeakPolarHBondContact O-CG1 3.44Å; L514-I518 PolarHBondContact O-N 3.17Å
515R94.2Very high89.6Confident121 Ų121104.7 Ų104.746%0.45751%0.508SS..Hα-helixtrans-60.5-39.7174.8-173.2-177.1-175.1-163.85.1111.7Y511 I512 I513 R519Y511-R515 WeakPolarHBondContact O-CB 3.43Å; Y511-R515 PolarHBondContact O-N 3.3Å; I512-R515 PolarHBondContact O-N 3.42Å; I513-R515 VanDerWaalsContact C-N 3.32Å; I513-R515 PolarHBondContact O-N 2.89Å; R515-R519 VanDerWaalsContact NH2-NH2 3.2Å; R515-R519 WeakPolarHBondContact O-CB 3.43Å; R515-R519 VanDerWaalsContact O-CG 3.28Å; R515-R519 WeakPolarHBondContact O-CG 3.47Å; R515-R519 PolarHBondContact O-N 2.65Å
516A92.9Very high87.7Confident55 Ų55102.7 Ų102.746%0.45551%0.509SS..Hα-helixtrans-67.6-43.2176.300000112.3I512 I513 L514 R519 K520I512-A516 WeakPolarHBondContact O-CB 3.44Å; I512-A516 PolarHBondContact O-N 3.4Å; I513-A516 WeakPolarHBondContact O-CB 3.47Å; I513-A516 PolarHBondContact O-N 3.47Å; I513-A516 VanDerWaalsContact O-N 3.09Å; L514-A516 VanDerWaalsContact C-N 3.3Å; L514-A516 PolarHBondContact O-N 3.32Å; A516-R519 PolarHBondContact O-N 2.95Å; A516-K520 WeakPolarHBondContact O-CB 3.24Å; A516-K520 PolarHBondContact O-N 2.89Å
517V92.6Very high85.8Confident70 Ų70103.3 Ų103.342%0.42451%0.513SS..Hα-helixtrans-64.2-47.4176.4171.70000111.1I513 L514 R519 K520 I521I513-V517 HydrophobicContact CG2-CG2 4.29Å; I513-V517 WeakPolarHBondContact O-CG2 3.46Å; I513-V517 PolarHBondContact O-N 3.29Å; L514-V517 PolarHBondContact O-N 3.46Å; V517-R519 PolarHBondContact O-N 2.9Å; V517-K520 PolarHBondContact O-N 3.47Å; V517-K520 VanDerWaalsContact O-N 3.13Å; V517-I521 HydrophobicContact CG1-CD1 3.75Å; V517-I521 HydrophobicContact CG1-CG1 4.4Å; V517-I521 WeakPolarHBondContact O-CG1 3.4Å; V517-I521 PolarHBondContact O-N 3.33Å
518I91.7Very high83.8Confident80 Ų80103.9 Ų103.941%0.4151%0.513SS..Hα-helixtrans-58.1-48.6175.4-71.2171.9000109.9L514 K520 I521 F522L514-I518 HydrophobicContact CD1-CD1 3.95Å; L514-I518 HydrophobicContact CD1-CG1 4.15Å; L514-I518 HydrophobicContact CD2-CD1 4.47Å; L514-I518 HydrophobicContact CG-CD1 3.8Å; L514-I518 HydrophobicContact CG-CG1 4.39Å; L514-I518 WeakPolarHBondContact O-CB 3.46Å; L514-I518 VanDerWaalsContact O-CG1 3.25Å; L514-I518 WeakPolarHBondContact O-CG1 3.44Å; L514-I518 PolarHBondContact O-N 3.17Å; I518-K520 VanDerWaalsContact C-N 3.31Å; I518-K520 PolarHBondContact O-N 2.91Å; I518-I521 PolarHBondContact O-N 3.36Å; I518-F522 HydrophobicContact CG2-CD2 3.67Å; I518-F522 HydrophobicContact CG2-CE2 3.94Å; I518-F522 WeakPolarHBondContact O-CD2 3.05Å; I518-F522 PolarHBondContact O-N 3.05Å
519R88.9Confident81.9Confident132 Ų132102.7 Ų102.750%0.49852%0.519SS..Hα-helixtrans-55-47.6174.5-80.5176.8170.5-174-5.4111.1R515 A516 V517 I521 F522 F523R515-R519 VanDerWaalsContact NH2-NH2 3.2Å; R515-R519 WeakPolarHBondContact O-CB 3.43Å; R515-R519 VanDerWaalsContact O-CG 3.28Å; R515-R519 WeakPolarHBondContact O-CG 3.47Å; R515-R519 PolarHBondContact O-N 2.65Å; A516-R519 PolarHBondContact O-N 2.95Å; V517-R519 PolarHBondContact O-N 2.9Å; R519-I521 PolarHBondContact O-N 3.25Å; R519-F522 PolarHBondContact O-N 2.8Å; R519-F523 HydrophobicContact CB-CD2 4.27Å; R519-F523 HydrophobicContact CG-CE2 4.42Å; R519-F523 VanDerWaalsContact O-CB 3.31Å; R519-F523 WeakPolarHBondContact O-CB 3.31Å; R519-F523 VanDerWaalsContact O-CD2 3.25Å; R519-F523 WeakPolarHBondContact O-CD2 3.21Å; R519-F523 PolarHBondContact O-N 2.78Å
520K87.4Confident79.8Confident168 Ų168107.6 Ų107.673%0.7354%0.538SS*.Hα-helixtrans-61.5-44.3-179.9-164.9177.2-179.6-178.40112.4A516 V517 I518 S524A516-K520 WeakPolarHBondContact O-CB 3.24Å; A516-K520 PolarHBondContact O-N 2.89Å; V517-K520 PolarHBondContact O-N 3.47Å; V517-K520 VanDerWaalsContact O-N 3.13Å; I518-K520 VanDerWaalsContact C-N 3.31Å; I518-K520 PolarHBondContact O-N 2.91Å; K520-S524 WeakPolarHBondContact O-CB 3.18Å; K520-S524 PolarHBondContact O-N 2.98Å
521I86.6Confident77.9Confident95 Ų95108.2 Ų108.249%0.48754%0.542SS..Hα-helixtrans-66.1-45.6-179.9-66.7170.2000111.5V517 I518 R519 K525V517-I521 HydrophobicContact CG1-CD1 3.75Å; V517-I521 HydrophobicContact CG1-CG1 4.4Å; V517-I521 WeakPolarHBondContact O-CG1 3.4Å; V517-I521 PolarHBondContact O-N 3.33Å; I518-I521 PolarHBondContact O-N 3.36Å; R519-I521 PolarHBondContact O-N 3.25Å; I521-K525 PolarHBondContact O-N 2.97Å
522F81.6Confident75.6Confident143 Ų143110.7 Ų110.763%0.62756%0.556SS**Hα-helixtrans-76.2-35.8-177.7-79.3-84.5000113.1I518 R519I518-F522 HydrophobicContact CG2-CD2 3.67Å; I518-F522 HydrophobicContact CG2-CE2 3.94Å; I518-F522 WeakPolarHBondContact O-CD2 3.05Å; I518-F522 PolarHBondContact O-N 3.05Å; R519-F522 PolarHBondContact O-N 2.8Å
523F73.6Confident73.5Confident152 Ų152113 Ų11367%0.66757%0.574SS**Hα-helixtrans-75.4-30.9176.1-80-78.8000113.1R519 K525 C526 S527R519-F523 HydrophobicContact CB-CD2 4.27Å; R519-F523 HydrophobicContact CG-CE2 4.42Å; R519-F523 VanDerWaalsContact O-CB 3.31Å; R519-F523 WeakPolarHBondContact O-CB 3.31Å; R519-F523 VanDerWaalsContact O-CD2 3.25Å; R519-F523 WeakPolarHBondContact O-CD2 3.21Å; R519-F523 PolarHBondContact O-N 2.78Å; F523-K525 VanDerWaalsContact C-N 3.34Å; F523-K525 PolarHBondContact O-N 3.23Å; F523-C526 PolarHBondContact O-N 3.39Å; F523-S527 PolarHBondContact O-N 2.66Å
524S65.7Low71Confident62 Ų62120 Ų12043%0.43460%0.604SS.*Hα-helixtrans-66.3-33.6174.2-172.60000112.8K520 C526 S527 E528K520-S524 WeakPolarHBondContact O-CB 3.18Å; K520-S524 PolarHBondContact O-N 2.98Å; S524-C526 VanDerWaalsContact C-N 3.33Å; S524-S527 PolarHBondContact O-N 3.22Å; S524-S527 PolarHBondContact O-OG 3.44Å; S524-E528 PolarHBondContact O-N 2.93Å
525K58.4Low69.8Low141 Ų141121 Ų12161%0.61361%0.608SS**Hα-helixtrans-68.8-31.4174.3-78.6-174.5175.2-177.20112.4I521 F523 S527 V529I521-K525 PolarHBondContact O-N 2.97Å; F523-K525 VanDerWaalsContact C-N 3.34Å; F523-K525 PolarHBondContact O-N 3.23Å; K525-S527 VanDerWaalsContact C-N 3.34Å; K525-V529 WeakPolarHBondContact O-CG2 3.43Å; K525-V529 PolarHBondContact O-N 2.9Å
526C57.7Low68.5Low87 Ų87121 Ų12159%0.58862%0.616SS**Hα-helixtrans-70.6-26.7174-87.90000113.5F523 S524F523-C526 PolarHBondContact O-N 3.39Å; S524-C526 VanDerWaalsContact C-N 3.33Å
527S58.1Low67.2Low71 Ų71124.7 Ų124.750%0.49763%0.625SS.*Hα-helixtrans-78.3-36.7175.351.80000113.1F523 S524 K525 K530 S531F523-S527 PolarHBondContact O-N 2.66Å; S524-S527 PolarHBondContact O-N 3.22Å; S524-S527 PolarHBondContact O-OG 3.44Å; K525-S527 VanDerWaalsContact C-N 3.34Å; S527-K530 PolarHBondContact O-N 3.17Å; S527-S531 PolarHBondContact O-N 3.12Å
528E55.7Low65.7Low129 Ų129127.9 Ų127.960%0.60364%0.637SS**Hα-helixtrans-70.7-32177.4-80.8-175.1160.700113.4S524 K530 S531S524-E528 PolarHBondContact O-N 2.93Å; E528-K530 PolarHBondContact O-N 3.21Å; E528-S531 PolarHBondContact O-N 3.2Å; E528-S531 PolarHBondContact O-OG 2.68Å
529V57Low64Low109 Ų109130.9 Ų130.966%0.66165%0.651SS**Hα-helixtrans-65.9-25.9174.1174.70000111.3K525 T533K525-V529 WeakPolarHBondContact O-CG2 3.43Å; K525-V529 PolarHBondContact O-N 2.9Å; V529-T533 PolarHBondContact O-OG1 3.49Å
530K54.2Low62.4Low169 Ų169130.8 Ų130.874%0.73566%0.661SS**Hα-helixtrans-78.5-25.8175.5-76.8-174.5173-174.20113.8S527 E528 T533S527-K530 PolarHBondContact O-N 3.17Å; E528-K530 PolarHBondContact O-N 3.21Å; K530-T533 PolarHBondContact O-OG1 3.4Å
531S55.1Low60.6Low82 Ų82128.1 Ų128.157%0.57366%0.656SS**Hα-helixtrans-90.2-4.5-177.372.70000115S527 E528S527-S531 PolarHBondContact O-N 3.12Å; E528-S531 PolarHBondContact O-N 3.2Å; E528-S531 PolarHBondContact O-OG 2.68Å
532K49.6Very low58.6Low189 Ų189130.7 Ų130.782%0.82267%0.669SS**THydrogen-bonded Turntrans-97.59.6173.5-81.1-172.7175.2179.90114.1
533T52.6Low56.7Low121 Ų121129.7 Ų129.774%0.74267%0.673SS**  trans-113.413.7179.419.80000113.8V529 K530V529-T533 PolarHBondContact O-OG1 3.49Å; K530-T533 PolarHBondContact O-OG1 3.4Å
534E42.6Very low55.2Low244 Ų244127.6 Ų127.6100%1.1467%0.673SS**  trans-105.50160-71.7-178.516500108.3

Retrieved 534 of 534 residues in 521.6 ms (Link to these results)