A0A061HXR0_CRIGR Loading...

Free fatty acid receptor 1

G-protein coupled receptor for medium and long chain saturated and unsaturated fatty acids that plays an important role in glucose homeostasis. Fatty acid binding increases glucose-stimulated insulin secretion, and may also enhance the secretion of glucagon-like peptide 1 (GLP-1). May also play a role in bone homeostasis; receptor signaling activates pathways that inhibit osteoclast differentiation. Ligand binding leads to a conformation change that triggers signaling via G-proteins that activate phospholipase C, leading to an increase of the intracellular calcium concentration. Seems to act through a G(q) and G(i)-mediated pathway. Mediates the anti-inflammatory effects of omega-3 polyunsaturated fatty acids (PUFAs) via inhibition of NLRP3 inflammasome activation.

AlphaFold DB , UniProt , Accession A0A061HXR0, Species CRIGR (Cricetulus griseus, Chinese hamster), Gene LOC113837332, Length 300 aa.

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(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	49.9	Very low	88	Confident	226 Å²	226	77.4 Å²	77.4	100%	1.113	44%	0.438	S	S	*	.				0	110.9	0	-81.1	178.6	-107.4	0	0	108.1
2	A	69.7	Low	88.8	Confident	87 Å²	87	71.7 Å²	71.7	72%	0.719	41%	0.405	S	S	*	.	P	Polyproline II helix	trans	-83	131.3	172.7	0	0	0	0	0	108.8
3	L	82.7	Confident	89.6	Confident	55 Å²	55	70.2 Å²	70.2	29%	0.288	40%	0.398	S	S	.	.	P	Polyproline II helix	trans	-66	139.7	170.4	-75.3	97.2	0	0	0	109.2	L7 L11 L260 I263	L3-L7 HydrophobicContact CD2-CD2 3.85Å; L3-L7 HydrophobicContact CD2-CG 4.09Å; L3-L7 HydrophobicContact CG-CD2 4.41Å; L3-L11 HydrophobicContact CD2-CD1 3.9Å; L3-L260 HydrophobicContact CD1-CB 4.44Å; L3-L260 HydrophobicContact CD1-CD1 4.23Å; L3-I263 HydrophobicContact CD2-CD1 3.96Å
4	S	92.5	Very high	90.2	Very high	54 Å²	54	68.8 Å²	68.8	38%	0.378	40%	0.395	S	S	.	.	P	Polyproline II helix	trans	-64.4	149.7	173.1	65.5	0	0	0	0	110.7	Q6 L7 S8	S4-Q6 PolarHBondContact O-N 3.06Å; S4-L7 PolarHBondContact O-N 3.28Å; S4-L7 VanDerWaalsContact OG-CB 3.26Å; S4-L7 WeakPolarHBondContact OG-CB 3.44Å; S4-L7 PolarHBondContact OG-N 3.4Å; S4-S8 PolarHBondContact O-N 3.21Å; S4-S8 PolarHBondContact O-OG 3.19Å; S4-S8 VanDerWaalsContact O-OG 3.11Å
5	P	92.9	Very high	90.8	Very high	43 Å²	43	64.2 Å²	64.2	28%	0.279	37%	0.369	S	S	.	.	H	α-helix	trans	-53.4	-41	175.2	-29.9	37.4	0	0	0	113	S8 F9 A66	P5-S8 PolarHBondContact O-N 3.09Å; P5-F9 WeakPolarHBondContact O-CB 3.22Å; P5-F9 PolarHBondContact O-N 3.28Å; P5-A66 WeakPolarHBondContact CB-O 3.31Å
6	Q	95.4	Very high	91.3	Very high	125 Å²	125	64.3 Å²	64.3	58%	0.584	36%	0.363	S	S	*	.	H	α-helix	trans	-66.2	-40.9	-179.7	-60.8	80.9	0.3	0	0	111.9	S4 A10	S4-Q6 PolarHBondContact O-N 3.06Å; Q6-A10 WeakPolarHBondContact O-CB 3.2Å; Q6-A10 PolarHBondContact O-N 3.27Å
7	L	95.6	Very high	91.7	Very high	84 Å²	84	63.9 Å²	63.9	44%	0.44	37%	0.37	S	S	.	.	H	α-helix	trans	-67.2	-43.2	176.7	179.9	59	0	0	0	111	L3 S4 F9 A10 L11	L3-L7 HydrophobicContact CD2-CD2 3.85Å; L3-L7 HydrophobicContact CD2-CG 4.09Å; L3-L7 HydrophobicContact CG-CD2 4.41Å; S4-L7 PolarHBondContact O-N 3.28Å; S4-L7 VanDerWaalsContact OG-CB 3.26Å; S4-L7 WeakPolarHBondContact OG-CB 3.44Å; S4-L7 PolarHBondContact OG-N 3.4Å; L7-F9 PolarHBondContact O-N 3.13Å; L7-A10 PolarHBondContact O-N 3.07Å; L7-L11 HydrophobicContact CD1-CD1 4.18Å; L7-L11 HydrophobicContact CD1-CG 4.27Å; L7-L11 HydrophobicContact CG-CD1 4.04Å; L7-L11 VanDerWaalsContact O-CG 3.28Å; L7-L11 WeakPolarHBondContact O-CG 3.45Å; L7-L11 PolarHBondContact O-N 2.72Å
8	S	95.7	Very high	92.1	Very high	15 Å²	15	65.2 Å²	65.2	11%	0.105	38%	0.375	C	S	.	.	H	α-helix	trans	-61.4	-45.5	176.9	-56.8	0	0	0	0	111.4	S4 P5 L11 Y12	S4-S8 PolarHBondContact O-N 3.21Å; S4-S8 PolarHBondContact O-OG 3.19Å; S4-S8 VanDerWaalsContact O-OG 3.11Å; P5-S8 PolarHBondContact O-N 3.09Å; S8-L11 PolarHBondContact O-N 2.86Å; S8-Y12 WeakPolarHBondContact O-CD2 3.48Å; S8-Y12 PolarHBondContact O-N 3.37Å; S8-Y12 VanDerWaalsContact O-N 3.1Å
9	F	97	Very high	92.4	Very high	72 Å²	72	61.7 Å²	61.7	32%	0.316	36%	0.355	S	S	.	.	H	α-helix	trans	-55.4	-51.5	173.2	174.9	-89.7	0	0	0	111.5	P5 L7 L11 Y12 V13 A63 L67	P5-F9 WeakPolarHBondContact O-CB 3.22Å; P5-F9 PolarHBondContact O-N 3.28Å; L7-F9 PolarHBondContact O-N 3.13Å; F9-L11 VanDerWaalsContact C-N 3.31Å; F9-L11 PolarHBondContact O-N 3.44Å; F9-Y12 PolarHBondContact O-N 3.13Å; F9-V13 HydrophobicContact CD1-CG2 4.18Å; F9-V13 HydrophobicContact CD2-CG2 4.41Å; F9-V13 HydrophobicContact CE1-CG2 3.79Å; F9-V13 HydrophobicContact CE2-CG2 4.04Å; F9-V13 HydrophobicContact CG-CG2 4.47Å; F9-V13 HydrophobicContact CZ-CG2 3.71Å; F9-V13 WeakPolarHBondContact O-CG2 3.1Å; F9-V13 PolarHBondContact O-N 2.92Å; F9-A63 HydrophobicContact CD2-CB 3.7Å; F9-A63 WeakPolarHBondContact CD2-O 3.38Å; F9-A63 HydrophobicContact CE2-CB 4.05Å; F9-A63 HydrophobicContact CG-CB 4.39Å; F9-L67 HydrophobicContact CB-CB 4.48Å; F9-L67 HydrophobicContact CB-CD1 4.48Å; F9-L67 HydrophobicContact CD2-CB 4.06Å; F9-L67 HydrophobicContact CD2-CD2 4.15Å; F9-L67 HydrophobicContact CE2-CD2 4.34Å
10	A	97.9	Very high	92.7	Very high	43 Å²	43	62.4 Å²	62.4	36%	0.355	35%	0.354	S	S	.	.	H	α-helix	trans	-60.1	-39.8	-179.4	0	0	0	0	0	112.3	Q6 L7 S14	Q6-A10 WeakPolarHBondContact O-CB 3.2Å; Q6-A10 PolarHBondContact O-N 3.27Å; L7-A10 PolarHBondContact O-N 3.07Å; A10-S14 VanDerWaalsContact O-CB 3.25Å; A10-S14 WeakPolarHBondContact O-CB 3.46Å; A10-S14 PolarHBondContact O-N 3.3Å; A10-S14 PolarHBondContact O-OG 2.85Å
11	L	98.2	Very high	92.9	Very high	47 Å²	47	62.2 Å²	62.2	25%	0.246	36%	0.355	C	S	.	.	H	α-helix	trans	-67.1	-41.7	178.9	-70.4	168.7	0	0	0	112.5	L3 L7 S8 F9 A15 I263 W267	L3-L11 HydrophobicContact CD2-CD1 3.9Å; L7-L11 HydrophobicContact CD1-CD1 4.18Å; L7-L11 HydrophobicContact CD1-CG 4.27Å; L7-L11 HydrophobicContact CG-CD1 4.04Å; L7-L11 VanDerWaalsContact O-CG 3.28Å; L7-L11 WeakPolarHBondContact O-CG 3.45Å; L7-L11 PolarHBondContact O-N 2.72Å; S8-L11 PolarHBondContact O-N 2.86Å; F9-L11 VanDerWaalsContact C-N 3.31Å; F9-L11 PolarHBondContact O-N 3.44Å; L11-A15 WeakPolarHBondContact O-CB 3.42Å; L11-A15 PolarHBondContact O-N 3.46Å; L11-I263 HydrophobicContact CB-CG2 3.91Å; L11-I263 HydrophobicContact CD1-CD1 4.22Å; L11-I263 HydrophobicContact CD1-CG2 4.01Å; L11-I263 HydrophobicContact CG-CG2 4.49Å; L11-W267 HydrophobicContact CD2-CZ2 4.13Å; L11-W267 PolarHBondContact O-NE1 2.93Å
12	Y	98.5	Very high	95.1	Very high	9 Å²	9	53.1 Å²	53.1	4%	0.035	31%	0.311	C	S	.	.	H	α-helix	trans	-68.5	-43.2	175.5	-76	-62.2	0	0	0	112.3	S8 F9 S14 A15 F16 L59 K62 A66 L262 I263 A266	S8-Y12 WeakPolarHBondContact O-CD2 3.48Å; S8-Y12 PolarHBondContact O-N 3.37Å; S8-Y12 VanDerWaalsContact O-N 3.1Å; F9-Y12 PolarHBondContact O-N 3.13Å; Y12-S14 VanDerWaalsContact C-N 3.32Å; Y12-S14 PolarHBondContact O-N 3.45Å; Y12-A15 PolarHBondContact O-N 3.13Å; Y12-F16 PolarHBondContact O-N 3.23Å; Y12-L59 HydrophobicContact CD1-CD2 4.26Å; Y12-K62 HydrophobicContact CD1-CB 4.47Å; Y12-K62 HydrophobicContact CD1-CG 4.28Å; Y12-K62 HydrophobicContact CD2-CG 4.36Å; Y12-K62 HydrophobicContact CE1-CB 4.44Å; Y12-K62 HydrophobicContact CE1-CG 3.79Å; Y12-K62 HydrophobicContact CE2-CG 3.9Å; Y12-A66 HydrophobicContact CD2-CB 4.39Å; Y12-A66 HydrophobicContact CE2-CB 4.34Å; Y12-L262 WeakPolarHBondContact OH-CB 3.42Å; Y12-I263 HydrophobicContact CE1-CG1 4.32Å; Y12-I263 HydrophobicContact CE2-CG1 3.9Å; Y12-A266 HydrophobicContact CD1-CB 3.79Å; Y12-A266 HydrophobicContact CE1-CB 3.66Å
13	V	98.4	Very high	96.4	Very high	53 Å²	53	49 Å²	49	32%	0.321	28%	0.277	S	S	.	.	H	α-helix	trans	-63	-40.5	176.5	171.1	0	0	0	0	111	F9 F16 A17 A63	F9-V13 HydrophobicContact CD1-CG2 4.18Å; F9-V13 HydrophobicContact CD2-CG2 4.41Å; F9-V13 HydrophobicContact CE1-CG2 3.79Å; F9-V13 HydrophobicContact CE2-CG2 4.04Å; F9-V13 HydrophobicContact CG-CG2 4.47Å; F9-V13 HydrophobicContact CZ-CG2 3.71Å; F9-V13 WeakPolarHBondContact O-CG2 3.1Å; F9-V13 PolarHBondContact O-N 2.92Å; V13-F16 PolarHBondContact O-N 3.4Å; V13-A17 VanDerWaalsContact O-CB 3.31Å; V13-A17 WeakPolarHBondContact O-CB 3.37Å; V13-A17 PolarHBondContact O-N 2.9Å; V13-A63 HydrophobicContact CG2-CB 3.93Å
14	S	98.6	Very high	97.1	Very high	50 Å²	50	51 Å²	51	35%	0.35	29%	0.287	S	S	.	.	H	α-helix	trans	-63.8	-44.3	175.9	-59.9	0	0	0	0	111.6	A10 Y12 F16 A17 L18	A10-S14 VanDerWaalsContact O-CB 3.25Å; A10-S14 WeakPolarHBondContact O-CB 3.46Å; A10-S14 PolarHBondContact O-N 3.3Å; A10-S14 PolarHBondContact O-OG 2.85Å; Y12-S14 VanDerWaalsContact C-N 3.32Å; Y12-S14 PolarHBondContact O-N 3.45Å; S14-F16 VanDerWaalsContact C-N 3.31Å; S14-F16 PolarHBondContact O-N 3.48Å; S14-A17 PolarHBondContact O-N 3.28Å; S14-L18 WeakPolarHBondContact O-CB 3.4Å; S14-L18 WeakPolarHBondContact O-CG 3.24Å; S14-L18 PolarHBondContact O-N 3.24Å
15	A	98.5	Very high	97.2	Very high	0 Å²	0	52.5 Å²	52.5	0%	0	29%	0.291	C	S	.	.	H	α-helix	trans	-60.5	-40.4	175.6	0	0	0	0	0	111.9	L11 Y12 G19 L59 W267 V269	L11-A15 WeakPolarHBondContact O-CB 3.42Å; L11-A15 PolarHBondContact O-N 3.46Å; Y12-A15 PolarHBondContact O-N 3.13Å; A15-G19 VanDerWaalsContact O-CA 3.29Å; A15-G19 WeakPolarHBondContact O-CA 3.44Å; A15-G19 PolarHBondContact O-N 3.23Å; A15-L59 HydrophobicContact CB-CD1 3.82Å; A15-W267 HydrophobicContact CB-CD2 4.34Å; A15-W267 HydrophobicContact CB-CG 4.25Å; A15-V269 WeakPolarHBondContact O-CG2 3.3Å
16	F	98.7	Very high	97.2	Very high	65 Å²	65	50.7 Å²	50.7	29%	0.285	28%	0.279	S	S	.	.	H	α-helix	trans	-63.5	-53.8	173	170.3	-110.7	0	0	0	112.3	Y12 V13 S14 L18 G19 F20 A56 L59 P60	Y12-F16 PolarHBondContact O-N 3.23Å; V13-F16 PolarHBondContact O-N 3.4Å; S14-F16 VanDerWaalsContact C-N 3.31Å; S14-F16 PolarHBondContact O-N 3.48Å; F16-L18 PolarHBondContact O-N 2.97Å; F16-G19 PolarHBondContact O-N 3.31Å; F16-F20 HydrophobicContact CD2-CB 4.14Å; F16-F20 HydrophobicContact CE2-CB 3.96Å; F16-F20 AromaticContact CE2-CD2 3.95Å; F16-F20 HydrophobicContact CE2-CD2 3.95Å; F16-F20 HydrophobicContact CE2-CG 4.07Å; F16-F20 VanDerWaalsContact O-CB 3.28Å; F16-F20 WeakPolarHBondContact O-CB 3.38Å; F16-F20 PolarHBondContact O-N 3.41Å; F16-A56 WeakPolarHBondContact CD2-O 3.44Å; F16-L59 HydrophobicContact CB-CB 4.13Å; F16-L59 HydrophobicContact CB-CD1 4.46Å; F16-P60 HydrophobicContact CB-CG 4.39Å; F16-P60 HydrophobicContact CD1-CG 3.95Å; F16-P60 HydrophobicContact CD2-CG 3.91Å; F16-P60 HydrophobicContact CE1-CG 4.17Å; F16-P60 HydrophobicContact CE2-CG 4.12Å; F16-P60 HydrophobicContact CG-CG 3.8Å; F16-P60 HydrophobicContact CZ-CG 4.25Å
17	A	98.6	Very high	97.2	Very high	58 Å²	58	46 Å²	46	48%	0.479	26%	0.258	S	S	.	.	H	α-helix	trans	-60.1	-34.3	-174.6	0	0	0	0	0	112.5	V13 S14 P21	V13-A17 VanDerWaalsContact O-CB 3.31Å; V13-A17 WeakPolarHBondContact O-CB 3.37Å; V13-A17 PolarHBondContact O-N 2.9Å; S14-A17 PolarHBondContact O-N 3.28Å; A17-P21 WeakPolarHBondContact O-CD 3.31Å; A17-P21 WeakPolarHBondContact O-CG 3.44Å
18	L	98.4	Very high	97.1	Very high	87 Å²	87	50.8 Å²	50.8	46%	0.455	27%	0.27	S	S	.	.	H	α-helix	trans	-85.7	-46.2	175.1	-63.2	174.4	0	0	0	112	S14 F16 P21 L22 W267 V270	S14-L18 WeakPolarHBondContact O-CB 3.4Å; S14-L18 WeakPolarHBondContact O-CG 3.24Å; S14-L18 PolarHBondContact O-N 3.24Å; F16-L18 PolarHBondContact O-N 2.97Å; L18-P21 WeakPolarHBondContact O-CD 3.46Å; L18-P21 WeakPolarHBondContact O-CG 3.32Å; L18-L22 WeakPolarHBondContact O-CB 3.38Å; L18-L22 WeakPolarHBondContact O-CD1 3.26Å; L18-L22 WeakPolarHBondContact O-CG 3.5Å; L18-L22 PolarHBondContact O-N 2.91Å; L18-W267 HydrophobicContact CD1-CH2 4.46Å; L18-W267 HydrophobicContact CD1-CZ3 4.41Å; L18-V270 HydrophobicContact CB-CG1 4.32Å; L18-V270 HydrophobicContact CB-CG2 3.89Å
19	G	98.1	Very high	96.9	Very high	0 Å²	0	50.6 Å²	50.6	0%	0	27%	0.27	C	S	.	.	H	α-helix	trans	-67.9	-42.4	-172.2	0	0	0	0	0	113.8	A15 F16 L22 N23	A15-G19 VanDerWaalsContact O-CA 3.29Å; A15-G19 WeakPolarHBondContact O-CA 3.44Å; A15-G19 PolarHBondContact O-N 3.23Å; F16-G19 PolarHBondContact O-N 3.31Å; G19-L22 PolarHBondContact O-N 3.49Å; G19-N23 PolarHBondContact O-N 3.2Å; G19-N23 PolarHBondContact O-ND2 3.39Å
20	F	98.3	Very high	96.6	Very high	75 Å²	75	47.2 Å²	47.2	33%	0.329	26%	0.255	S	S	.	.	H	α-helix	trans	-58.7	-54.7	-178.6	-173	-90.3	0	0	0	112.7	F16 L22 N23 L24 L53 A56 I57	F16-F20 HydrophobicContact CD2-CB 4.14Å; F16-F20 HydrophobicContact CE2-CB 3.96Å; F16-F20 AromaticContact CE2-CD2 3.95Å; F16-F20 HydrophobicContact CE2-CD2 3.95Å; F16-F20 HydrophobicContact CE2-CG 4.07Å; F16-F20 VanDerWaalsContact O-CB 3.28Å; F16-F20 WeakPolarHBondContact O-CB 3.38Å; F16-F20 PolarHBondContact O-N 3.41Å; F20-L22 PolarHBondContact O-N 2.86Å; F20-N23 PolarHBondContact O-N 3.37Å; F20-L24 PolarHBondContact O-N 3.23Å; F20-L24 VanDerWaalsContact O-N 3.09Å; F20-L53 HydrophobicContact CD2-CD2 3.87Å; F20-L53 HydrophobicContact CE2-CD2 4.11Å; F20-L53 HydrophobicContact CG-CD2 4.36Å; F20-A56 HydrophobicContact CB-CB 4.48Å; F20-I57 HydrophobicContact CD2-CG1 4.19Å; F20-I57 HydrophobicContact CE2-CD1 4.24Å; F20-I57 HydrophobicContact CE2-CG1 3.87Å
21	P	97.7	Very high	96.4	Very high	58 Å²	58	47.5 Å²	47.5	38%	0.377	25%	0.253	S	S	.	.	H	α-helix	trans	-66.1	-36.9	177.8	25.4	-34	0	0	0	112.8	A17 L18 N23 L24 L25	A17-P21 WeakPolarHBondContact O-CD 3.31Å; A17-P21 WeakPolarHBondContact O-CG 3.44Å; L18-P21 WeakPolarHBondContact O-CD 3.46Å; L18-P21 WeakPolarHBondContact O-CG 3.32Å; P21-N23 PolarHBondContact O-N 3.5Å; P21-L24 PolarHBondContact O-N 3.1Å; P21-L25 WeakPolarHBondContact O-CB 3.12Å; P21-L25 VanDerWaalsContact O-CG 3.29Å; P21-L25 WeakPolarHBondContact O-CG 3.2Å; P21-L25 PolarHBondContact O-N 3.1Å
22	L	96.6	Very high	96.1	Very high	36 Å²	36	48 Å²	48	19%	0.188	26%	0.263	C	S	.	.	H	α-helix	trans	-61.2	-45.6	178.2	-75.3	171.8	0	0	0	112	L18 G19 F20 L25 A26 V270 P273 L274 L279	L18-L22 WeakPolarHBondContact O-CB 3.38Å; L18-L22 WeakPolarHBondContact O-CD1 3.26Å; L18-L22 WeakPolarHBondContact O-CG 3.5Å; L18-L22 PolarHBondContact O-N 2.91Å; G19-L22 PolarHBondContact O-N 3.49Å; F20-L22 PolarHBondContact O-N 2.86Å; L22-L25 PolarHBondContact O-N 3.06Å; L22-A26 WeakPolarHBondContact O-CB 3.43Å; L22-A26 PolarHBondContact O-N 2.98Å; L22-V270 HydrophobicContact CD1-CG1 3.88Å; L22-P273 HydrophobicContact CB-CB 4.15Å; L22-P273 HydrophobicContact CB-CG 3.67Å; L22-P273 HydrophobicContact CD1-CG 4.48Å; L22-L274 HydrophobicContact CD2-CD2 4.41Å; L22-L279 HydrophobicContact CD2-CD1 3.92Å; L22-L279 HydrophobicContact CD2-CD2 4.11Å; L22-L279 WeakPolarHBondContact O-CD2 3.29Å
23	N	96.8	Very high	95.6	Very high	1 Å²	1	49.9 Å²	49.9	1%	0.005	27%	0.273	C	S	.	.	H	α-helix	trans	-70.1	-36.7	178.5	-73.2	-66.9	0	0	0	112.2	G19 F20 P21 L25 A26 I27 D52 L53 V269	G19-N23 PolarHBondContact O-N 3.2Å; G19-N23 PolarHBondContact O-ND2 3.39Å; F20-N23 PolarHBondContact O-N 3.37Å; P21-N23 PolarHBondContact O-N 3.5Å; N23-L25 VanDerWaalsContact C-N 3.32Å; N23-L25 PolarHBondContact O-N 2.88Å; N23-A26 PolarHBondContact O-N 3.46Å; N23-I27 WeakPolarHBondContact O-CB 3.28Å; N23-I27 VanDerWaalsContact O-CG1 3.28Å; N23-I27 WeakPolarHBondContact O-CG1 3.27Å; N23-I27 PolarHBondContact O-N 3.2Å; N23-D52 VanDerWaalsContact OD1-CB 3.31Å; N23-D52 WeakPolarHBondContact OD1-CB 3.41Å; N23-L53 HydrophobicContact CB-CD2 3.66Å; N23-L53 HydrophobicContact CB-CG 3.75Å; N23-V269 PolarHBondContact ND2-O 2.9Å
24	L	96.5	Very high	95.2	Very high	97 Å²	97	48.4 Å²	48.4	51%	0.508	27%	0.266	S	S	.	.	H	α-helix	trans	-60.3	-43.9	173.7	-174.7	63.1	0	0	0	111.5	F20 P21 R28	F20-L24 PolarHBondContact O-N 3.23Å; F20-L24 VanDerWaalsContact O-N 3.09Å; P21-L24 PolarHBondContact O-N 3.1Å; L24-R28 WeakPolarHBondContact O-CB 3.49Å; L24-R28 PolarHBondContact O-N 3.27Å
25	L	95.1	Very high	94.8	Very high	85 Å²	85	56.2 Å²	56.2	45%	0.445	29%	0.288	S	S	.	.	H	α-helix	trans	-64.8	-43.1	175.6	-71.9	172.2	0	0	0	112.1	P21 L22 N23 R28 G29 L279	P21-L25 WeakPolarHBondContact O-CB 3.12Å; P21-L25 VanDerWaalsContact O-CG 3.29Å; P21-L25 WeakPolarHBondContact O-CG 3.2Å; P21-L25 PolarHBondContact O-N 3.1Å; L22-L25 PolarHBondContact O-N 3.06Å; N23-L25 VanDerWaalsContact C-N 3.32Å; N23-L25 PolarHBondContact O-N 2.88Å; L25-R28 PolarHBondContact O-N 2.92Å; L25-G29 PolarHBondContact O-N 3.35Å; L25-L279 HydrophobicContact CB-CD2 4Å
26	A	92.4	Very high	94.4	Very high	4 Å²	4	62.4 Å²	62.4	3%	0.033	32%	0.32	C	S	.	.	H	α-helix	trans	-63.2	-44	178.3	0	0	0	0	0	111.9	L22 N23 G29 A30 P273 L279	L22-A26 WeakPolarHBondContact O-CB 3.43Å; L22-A26 PolarHBondContact O-N 2.98Å; N23-A26 PolarHBondContact O-N 3.46Å; A26-G29 PolarHBondContact O-N 2.89Å; A26-A30 VanDerWaalsContact O-CB 3.32Å; A26-A30 WeakPolarHBondContact O-CB 3.07Å; A26-A30 PolarHBondContact O-N 2.86Å; A26-P273 HydrophobicContact CB-CB 3.85Å; A26-L279 HydrophobicContact CB-CD2 4.13Å
27	I	95.1	Very high	93.9	Very high	28 Å²	28	66.9 Å²	66.9	14%	0.144	34%	0.335	C	S	.	.	H	α-helix	trans	-62.9	-46.8	174.2	-67.7	170.5	0	0	0	110.1	N23 G29 A30 V31 L46 L53	N23-I27 WeakPolarHBondContact O-CB 3.28Å; N23-I27 VanDerWaalsContact O-CG1 3.28Å; N23-I27 WeakPolarHBondContact O-CG1 3.27Å; N23-I27 PolarHBondContact O-N 3.2Å; I27-G29 VanDerWaalsContact C-N 3.3Å; I27-G29 PolarHBondContact O-N 2.89Å; I27-A30 PolarHBondContact O-N 3.45Å; I27-V31 HydrophobicContact CG2-CG2 4.06Å; I27-V31 WeakPolarHBondContact O-CB 3.12Å; I27-V31 VanDerWaalsContact O-CG2 3.31Å; I27-V31 WeakPolarHBondContact O-CG2 3.12Å; I27-V31 PolarHBondContact O-N 3.08Å; I27-L46 HydrophobicContact CG2-CD2 4.21Å; I27-L53 HydrophobicContact CD1-CD1 3.36Å; I27-L53 HydrophobicContact CD1-CG 4Å
28	R	94.3	Very high	93.4	Very high	184 Å²	184	67.2 Å²	67.2	69%	0.694	33%	0.328	S	S	*	.	H	α-helix	trans	-57.1	-45.3	178.3	-167.4	-176.9	85.1	156.5	4.2	111.5	L24 L25 A32	L24-R28 WeakPolarHBondContact O-CB 3.49Å; L24-R28 PolarHBondContact O-N 3.27Å; L25-R28 PolarHBondContact O-N 2.92Å; R28-A32 WeakPolarHBondContact O-CB 3.45Å; R28-A32 PolarHBondContact O-N 2.93Å
29	G	91.4	Very high	92.9	Very high	11 Å²	11	64 Å²	64	11%	0.113	31%	0.312	C	S	.	.	H	α-helix	trans	-60.8	-50.7	174.7	0	0	0	0	0	112	L25 A26 I27 V31 A32 H33	L25-G29 PolarHBondContact O-N 3.35Å; A26-G29 PolarHBondContact O-N 2.89Å; I27-G29 VanDerWaalsContact C-N 3.3Å; I27-G29 PolarHBondContact O-N 2.89Å; G29-V31 VanDerWaalsContact C-N 3.35Å; G29-V31 PolarHBondContact O-N 3.3Å; G29-A32 PolarHBondContact O-N 3.42Å; G29-H33 PolarHBondContact O-CD2 2.94Å; G29-H33 PolarHBondContact O-N 3.13Å
30	A	91	Very high	92.5	Very high	0 Å²	0	64.2 Å²	64.2	0%	0	31%	0.314	C	S	.	.	H	α-helix	trans	-60.1	-41.1	178.8	0	0	0	0	0	112.6	A26 I27 H33 A34 L42 T45 L46	A26-A30 VanDerWaalsContact O-CB 3.32Å; A26-A30 WeakPolarHBondContact O-CB 3.07Å; A26-A30 PolarHBondContact O-N 2.86Å; I27-A30 PolarHBondContact O-N 3.45Å; A30-H33 PolarHBondContact O-N 3.03Å; A30-A34 VanDerWaalsContact O-CB 3.29Å; A30-A34 WeakPolarHBondContact O-CB 3.28Å; A30-A34 PolarHBondContact O-N 2.84Å; A30-L42 HydrophobicContact CB-CD2 4.17Å; A30-T45 HydrophobicContact CB-CG2 4.06Å; A30-L46 HydrophobicContact CB-CD2 3.65Å; A30-L46 HydrophobicContact CB-CG 4.07Å
31	V	93.3	Very high	92.1	Very high	50 Å²	50	61.7 Å²	61.7	30%	0.303	30%	0.303	S	S	.	.	H	α-helix	trans	-63.8	-45	175.1	170	0	0	0	0	110.9	I27 G29 H33 A34 R35 L46	I27-V31 HydrophobicContact CG2-CG2 4.06Å; I27-V31 WeakPolarHBondContact O-CB 3.12Å; I27-V31 VanDerWaalsContact O-CG2 3.31Å; I27-V31 WeakPolarHBondContact O-CG2 3.12Å; I27-V31 PolarHBondContact O-N 3.08Å; G29-V31 VanDerWaalsContact C-N 3.35Å; G29-V31 PolarHBondContact O-N 3.3Å; V31-H33 VanDerWaalsContact C-N 3.28Å; V31-H33 PolarHBondContact O-N 3.37Å; V31-A34 PolarHBondContact O-N 3.37Å; V31-A34 VanDerWaalsContact O-N 3.13Å; V31-R35 HydrophobicContact CG1-CG 4.47Å; V31-R35 WeakPolarHBondContact O-CG 3.5Å; V31-R35 PolarHBondContact O-N 3.25Å; V31-L46 HydrophobicContact CG2-CD2 3.58Å
32	A	92	Very high	91.8	Very high	56 Å²	56	59.2 Å²	59.2	46%	0.463	29%	0.287	S	S	.	.	H	α-helix	trans	-58.8	-41.4	177.2	0	0	0	0	0	111.6	R28 G29	R28-A32 WeakPolarHBondContact O-CB 3.45Å; R28-A32 PolarHBondContact O-N 2.93Å; G29-A32 PolarHBondContact O-N 3.42Å
33	H	88	Confident	91.7	Very high	50 Å²	50	57.6 Å²	57.6	23%	0.231	28%	0.279	C	S	.	.	H	α-helix	trans	-67.9	-40.4	173	-74.6	-69.6	0	0	0	113.1	G29 A30 V31 R35 L36 R37 L42 G282	G29-H33 PolarHBondContact O-CD2 2.94Å; G29-H33 PolarHBondContact O-N 3.13Å; A30-H33 PolarHBondContact O-N 3.03Å; V31-H33 VanDerWaalsContact C-N 3.28Å; V31-H33 PolarHBondContact O-N 3.37Å; H33-R35 VanDerWaalsContact C-N 3.31Å; H33-R35 PolarHBondContact O-N 3.35Å; H33-L36 WeakPolarHBondContact O-CB 3.28Å; H33-L36 PolarHBondContact O-N 3.3Å; H33-L36 VanDerWaalsContact O-N 3.14Å; H33-R37 PolarHBondContact O-N 3.45Å; H33-L42 HydrophobicContact CB-CD1 3.88Å; H33-L42 HydrophobicContact CB-CD2 3.9Å; H33-G282 WeakPolarHBondContact NE2-CA 3.2Å
34	A	89.3	Confident	91.6	Very high	21 Å²	21	58.6 Å²	58.6	17%	0.174	28%	0.282	C	S	.	.	H	α-helix	trans	-63.5	-35.6	179.9	0	0	0	0	0	112.4	A30 V31 L36 R37 L38 L42 L46	A30-A34 VanDerWaalsContact O-CB 3.29Å; A30-A34 WeakPolarHBondContact O-CB 3.28Å; A30-A34 PolarHBondContact O-N 2.84Å; V31-A34 PolarHBondContact O-N 3.37Å; V31-A34 VanDerWaalsContact O-N 3.13Å; A34-L36 VanDerWaalsContact C-N 3.26Å; A34-L36 PolarHBondContact O-N 3.36Å; A34-R37 CarbonylContact O-C 3.57Å; A34-R37 PolarHBondContact O-N 3.14Å; A34-L38 HydrophobicContact CB-CD1 3.8Å; A34-L38 PolarHBondContact O-N 3.03Å; A34-L42 HydrophobicContact CB-CD1 4.42Å; A34-L46 HydrophobicContact CB-CD1 4.44Å
35	R	90.5	Very high	91.5	Very high	215 Å²	215	54.2 Å²	54.2	81%	0.811	26%	0.26	S	S	*	.	H	α-helix	trans	-61.9	-32.4	173.8	-72.9	177.5	-175.9	-170.9	0.8	112.8	V31 H33	V31-R35 HydrophobicContact CG1-CG 4.47Å; V31-R35 WeakPolarHBondContact O-CG 3.5Å; V31-R35 PolarHBondContact O-N 3.25Å; H33-R35 VanDerWaalsContact C-N 3.31Å; H33-R35 PolarHBondContact O-N 3.35Å
36	L	90.3	Very high	91.6	Very high	130 Å²	130	51.5 Å²	51.5	68%	0.681	25%	0.246	S	C	*	.	H	α-helix	trans	-79.5	-49.9	176.2	-64.1	171.6	0	0	0	111.4	H33 A34	H33-L36 WeakPolarHBondContact O-CB 3.28Å; H33-L36 PolarHBondContact O-N 3.3Å; H33-L36 VanDerWaalsContact O-N 3.14Å; A34-L36 VanDerWaalsContact C-N 3.26Å; A34-L36 PolarHBondContact O-N 3.36Å
37	R	87.4	Confident	91.8	Very high	158 Å²	158	52.6 Å²	52.6	60%	0.596	25%	0.25	S	S	*	.			trans	-158.3	110.3	176.8	-173.8	177.3	-177.1	-178.1	3.3	110.3	H33 A34 T39 L42	H33-R37 PolarHBondContact O-N 3.45Å; A34-R37 CarbonylContact O-C 3.57Å; A34-R37 PolarHBondContact O-N 3.14Å; R37-T39 HydrophobicContact CG-CG2 4.43Å; R37-T39 PolarHBondContact O-N 3.09Å; R37-L42 WeakPolarHBondContact O-CD1 3.49Å
38	L	88.9	Confident	91.9	Very high	65 Å²	65	51.4 Å²	51.4	34%	0.34	24%	0.244	S	C	.	.			trans	-69.1	123	173.7	-171.8	66.2	0	0	0	110.5	A34 L42 V43 P120	A34-L38 HydrophobicContact CB-CD1 3.8Å; A34-L38 PolarHBondContact O-N 3.03Å; L38-L42 HydrophobicContact CD1-CB 4.42Å; L38-V43 HydrophobicContact CD1-CG2 3.85Å; L38-V43 HydrophobicContact CD2-CG2 4.25Å; L38-V43 HydrophobicContact CG-CG2 4.13Å; L38-P120 HydrophobicContact CB-CG 4.43Å; L38-P120 HydrophobicContact CD2-CB 3.74Å; L38-P120 HydrophobicContact CD2-CG 4.25Å; L38-P120 HydrophobicContact CG-CB 3.98Å; L38-P120 HydrophobicContact CG-CG 4.14Å; L38-P120 WeakPolarHBondContact O-CG 3.31Å
39	T	89.1	Confident	92.1	Very high	20 Å²	20	42.9 Å²	42.9	12%	0.123	21%	0.213	C	C	.	.			trans	-117.9	153.6	174.2	70.9	0	0	0	0	110.1	R37 N41 L42 V43	R37-T39 HydrophobicContact CG-CG2 4.43Å; R37-T39 PolarHBondContact O-N 3.09Å; T39-N41 VanDerWaalsContact C-N 3.26Å; T39-N41 PolarHBondContact O-N 3.11Å; T39-L42 WeakPolarHBondContact O-CB 3.48Å; T39-L42 PolarHBondContact O-N 3.27Å; T39-L42 PolarHBondContact OG1-N 2.88Å; T39-V43 PolarHBondContact O-N 3.4Å
40	P	89	Confident	92.4	Very high	4 Å²	4	45.7 Å²	45.7	3%	0.026	23%	0.23	C	C	.	.	H	α-helix	trans	-42.8	-49	172.5	-40.1	44.1	0	0	0	114.8	L42 V43 Y44 R118 S123	P40-L42 VanDerWaalsContact C-N 3.29Å; P40-L42 PolarHBondContact O-N 2.9Å; P40-V43 WeakPolarHBondContact O-CB 3.47Å; P40-V43 PolarHBondContact O-N 3.23Å; P40-V43 VanDerWaalsContact O-N 3.11Å; P40-Y44 WeakPolarHBondContact O-CD2 3.48Å; P40-Y44 PolarHBondContact O-N 2.97Å; P40-R118 HydrophobicContact CG-CG 3.63Å; P40-S123 WeakPolarHBondContact CA-OG 3.35Å; P40-S123 WeakPolarHBondContact CB-OG 3.06Å
41	N	88.8	Confident	92.8	Very high	22 Å²	22	45.7 Å²	45.7	12%	0.118	23%	0.23	C	C	.	.	H	α-helix	trans	-65.1	-31.8	-178.5	-66.4	-4.2	0	0	0	112.8	T39 Y44 T45 L100	T39-N41 VanDerWaalsContact C-N 3.26Å; T39-N41 PolarHBondContact O-N 3.11Å; N41-Y44 PolarHBondContact O-N 2.98Å; N41-T45 PolarHBondContact O-N 3.33Å; N41-T45 PolarHBondContact O-OG1 3.34Å; N41-L100 HydrophobicContact CB-CD1 3.73Å
42	L	91.7	Very high	93	Very high	7 Å²	7	43.3 Å²	43.3	4%	0.037	22%	0.216	C	C	.	.	H	α-helix	trans	-68.4	-36.2	175	-76.9	168.1	0	0	0	111.5	A30 H33 A34 R37 L38 T39 P40 T45 L46 Y278	A30-L42 HydrophobicContact CB-CD2 4.17Å; H33-L42 HydrophobicContact CB-CD1 3.88Å; H33-L42 HydrophobicContact CB-CD2 3.9Å; A34-L42 HydrophobicContact CB-CD1 4.42Å; R37-L42 WeakPolarHBondContact O-CD1 3.49Å; L38-L42 HydrophobicContact CD1-CB 4.42Å; T39-L42 WeakPolarHBondContact O-CB 3.48Å; T39-L42 PolarHBondContact O-N 3.27Å; T39-L42 PolarHBondContact OG1-N 2.88Å; P40-L42 VanDerWaalsContact C-N 3.29Å; P40-L42 PolarHBondContact O-N 2.9Å; L42-T45 PolarHBondContact O-N 3.39Å; L42-L46 WeakPolarHBondContact O-CB 3.43Å; L42-L46 VanDerWaalsContact O-CG 3.26Å; L42-L46 WeakPolarHBondContact O-CG 3.46Å; L42-L46 PolarHBondContact O-N 3.07Å; L42-Y278 HydrophobicContact CD2-CD1 4.2Å; L42-Y278 HydrophobicContact CD2-CE1 3.46Å; L42-Y278 VanDerWaalsContact CD2-CE1 3.46Å
43	V	94.9	Very high	93.3	Very high	1 Å²	1	42 Å²	42	1%	0.006	20%	0.201	C	C	.	.	H	α-helix	trans	-60.9	-47.8	174.6	-178.9	0	0	0	0	110	L38 T39 P40 T45 L46 H47 P120 W124	L38-V43 HydrophobicContact CD1-CG2 3.85Å; L38-V43 HydrophobicContact CD2-CG2 4.25Å; L38-V43 HydrophobicContact CG-CG2 4.13Å; T39-V43 PolarHBondContact O-N 3.4Å; P40-V43 WeakPolarHBondContact O-CB 3.47Å; P40-V43 PolarHBondContact O-N 3.23Å; P40-V43 VanDerWaalsContact O-N 3.11Å; V43-T45 PolarHBondContact O-N 3.46Å; V43-L46 PolarHBondContact O-N 3.32Å; V43-H47 PolarHBondContact O-CD2 3.41Å; V43-H47 PolarHBondContact O-N 3.5Å; V43-H47 VanDerWaalsContact O-N 3.09Å; V43-P120 HydrophobicContact CG2-CB 4.39Å; V43-W124 HydrophobicContact CG1-CD2 3.93Å; V43-W124 HydrophobicContact CG1-CE3 4.41Å; V43-W124 HydrophobicContact CG1-CG 4.08Å
44	Y	94.9	Very high	93.8	Very high	22 Å²	22	43.1 Å²	43.1	9%	0.086	21%	0.208	C	C	.	.	H	α-helix	trans	-61.8	-41.8	176.4	-56.4	-42.1	0	0	0	112.5	P40 N41 H47 L48 A99 S123 V126 C127	P40-Y44 WeakPolarHBondContact O-CD2 3.48Å; P40-Y44 PolarHBondContact O-N 2.97Å; N41-Y44 PolarHBondContact O-N 2.98Å; Y44-H47 PolarHBondContact O-N 2.82Å; Y44-L48 VanDerWaalsContact O-CB 3.31Å; Y44-L48 WeakPolarHBondContact O-CB 3.37Å; Y44-L48 PolarHBondContact O-N 3.46Å; Y44-A99 HydrophobicContact CD1-CB 3.89Å; Y44-A99 HydrophobicContact CD2-CB 4.22Å; Y44-A99 HydrophobicContact CE1-CB 3.89Å; Y44-A99 HydrophobicContact CE2-CB 4.18Å; Y44-A99 WeakPolarHBondContact CE2-O 3.33Å; Y44-A99 HydrophobicContact CG-CB 4.09Å; Y44-S123 VanDerWaalsContact CZ-OG 3.31Å; Y44-S123 PolarHBondContact OH-OG 3.37Å; Y44-S123 VanDerWaalsContact OH-OG 3.1Å; Y44-V126 HydrophobicContact CE1-CB 4.04Å; Y44-V126 HydrophobicContact CE1-CG1 3.89Å; Y44-C127 VanDerWaalsContact CD1-SG 3.56Å
45	T	94.3	Very high	94.2	Very high	5 Å²	5	42.1 Å²	42.1	3%	0.031	20%	0.2	C	C	.	.	H	α-helix	trans	-63.4	-40.3	176.7	-60.5	0	0	0	0	112.5	A30 N41 L42 V43 L48 G49 Y278	A30-T45 HydrophobicContact CB-CG2 4.06Å; N41-T45 PolarHBondContact O-N 3.33Å; N41-T45 PolarHBondContact O-OG1 3.34Å; L42-T45 PolarHBondContact O-N 3.39Å; V43-T45 PolarHBondContact O-N 3.46Å; T45-L48 PolarHBondContact O-N 2.61Å; T45-G49 PolarHBondContact O-N 3.01Å; T45-Y278 HydrophobicContact CG2-CD2 3.47Å; T45-Y278 VanDerWaalsContact CG2-CD2 3.47Å; T45-Y278 HydrophobicContact CG2-CE2 3.81Å; T45-Y278 HydrophobicContact CG2-CG 4.16Å; T45-Y278 WeakPolarHBondContact OG1-CE2 3.39Å
46	L	96.2	Very high	94.6	Very high	29 Å²	29	31.9 Å²	31.9	15%	0.152	16%	0.162	C	C	.	.	H	α-helix	trans	-64.3	-46.1	177.5	-72.8	168	0	0	0	111.2	I27 A30 V31 A34 L42 V43 G49 C50	I27-L46 HydrophobicContact CG2-CD2 4.21Å; A30-L46 HydrophobicContact CB-CD2 3.65Å; A30-L46 HydrophobicContact CB-CG 4.07Å; V31-L46 HydrophobicContact CG2-CD2 3.58Å; A34-L46 HydrophobicContact CB-CD1 4.44Å; L42-L46 WeakPolarHBondContact O-CB 3.43Å; L42-L46 VanDerWaalsContact O-CG 3.26Å; L42-L46 WeakPolarHBondContact O-CG 3.46Å; L42-L46 PolarHBondContact O-N 3.07Å; V43-L46 PolarHBondContact O-N 3.32Å; L46-G49 PolarHBondContact O-N 3.28Å; L46-C50 PolarHBondContact O-N 2.86Å; L46-C50 PolarHBondContact O-SG 3.46Å
47	H	97.9	Very high	95	Very high	27 Å²	27	30.6 Å²	30.6	13%	0.125	15%	0.154	C	C	.	.	H	α-helix	trans	-63.8	-40.9	176.6	-85	-102	0	0	0	112.7	V43 Y44 C50 S51 F96 W124 C127 W131	V43-H47 PolarHBondContact O-CD2 3.41Å; V43-H47 PolarHBondContact O-N 3.5Å; V43-H47 VanDerWaalsContact O-N 3.09Å; Y44-H47 PolarHBondContact O-N 2.82Å; H47-C50 PolarHBondContact O-N 3.42Å; H47-S51 VanDerWaalsContact O-CB 3.3Å; H47-S51 WeakPolarHBondContact O-CB 3.34Å; H47-S51 PolarHBondContact O-N 3Å; H47-F96 HydrophobicContact CB-CD1 3.93Å; H47-F96 HydrophobicContact CB-CD2 4.19Å; H47-F96 HydrophobicContact CB-CE1 3.69Å; H47-F96 HydrophobicContact CB-CE2 3.96Å; H47-F96 HydrophobicContact CB-CG 4.21Å; H47-F96 HydrophobicContact CB-CZ 3.73Å; H47-W124 AromaticContact NE2-CE3 3.57Å; H47-W124 AromaticContact NE2-CZ3 3.24Å; H47-W124 WeakPolarHBondContact NE2-CZ3 3.34Å; H47-C127 VanDerWaalsContact CD2-SG 3.59Å; H47-C127 VanDerWaalsContact CG-SG 3.56Å; H47-W131 AromaticContact CE1-NE1 3.98Å; H47-W131 AromaticContact ND1-CD1 3.63Å; H47-W131 AromaticContact ND1-NE1 3.25Å; H47-W131 PolarHBondContact ND1-NE1 2.87Å
48	L	97.7	Very high	95.5	Very high	3 Å²	3	23.6 Å²	23.6	2%	0.016	13%	0.129	C	C	.	.	H	α-helix	trans	-58.9	-48.6	172.9	179	59.2	0	0	0	111.5	Y44 T45 C50 S51 D52 F96 L97 T276	Y44-L48 VanDerWaalsContact O-CB 3.31Å; Y44-L48 WeakPolarHBondContact O-CB 3.37Å; Y44-L48 PolarHBondContact O-N 3.46Å; T45-L48 PolarHBondContact O-N 2.61Å; L48-C50 PolarHBondContact O-N 3.5Å; L48-S51 WeakPolarHBondContact O-CB 3.45Å; L48-S51 PolarHBondContact O-N 3.43Å; L48-D52 VanDerWaalsContact O-CG 3.3Å; L48-D52 PolarHBondContact O-N 3.04Å; L48-F96 HydrophobicContact CB-CB 3.94Å; L48-F96 HydrophobicContact CB-CD2 4.42Å; L48-F96 HydrophobicContact CB-CG 4.49Å; L48-F96 HydrophobicContact CD1-CB 4.28Å; L48-L97 HydrophobicContact CD1-CG 4.37Å; L48-L97 HydrophobicContact CD2-CD2 3.7Å; L48-L97 HydrophobicContact CD2-CG 4.19Å; L48-T276 HydrophobicContact CD2-CG2 3.49Å; L48-T276 VanDerWaalsContact CD2-CG2 3.49Å
49	G	97.6	Very high	96	Very high	5 Å²	5	20.5 Å²	20.5	5%	0.052	11%	0.113	C	C	.	.	H	α-helix	trans	-62	-41.1	177.4	0	0	0	0	0	113.1	T45 L46 S51 D52 L53	T45-G49 PolarHBondContact O-N 3.01Å; L46-G49 PolarHBondContact O-N 3.28Å; G49-S51 VanDerWaalsContact C-N 3.34Å; G49-D52 PolarHBondContact O-N 3.3Å; G49-L53 WeakPolarHBondContact O-CB 3.48Å; G49-L53 PolarHBondContact O-N 3.31Å
50	C	98	Very high	96.4	Very high	69 Å²	69	21.8 Å²	21.8	47%	0.466	12%	0.121	S	C	.	.	H	α-helix	trans	-63.8	-40.7	174.9	-69.3	0	0	0	0	112	L46 H47 L48 L53 L54	L46-C50 PolarHBondContact O-N 2.86Å; L46-C50 PolarHBondContact O-SG 3.46Å; H47-C50 PolarHBondContact O-N 3.42Å; L48-C50 PolarHBondContact O-N 3.5Å; C50-L53 PolarHBondContact O-N 2.86Å; C50-L54 WeakPolarHBondContact O-CB 3.43Å; C50-L54 PolarHBondContact O-N 3.37Å
51	S	98.4	Very high	96.8	Very high	0 Å²	0	23.4 Å²	23.4	0%	0	13%	0.13	C	C	.	.	H	α-helix	trans	-60.7	-48.9	175.2	-166.9	0	0	0	0	111.1	H47 L48 G49 L53 L54 L55 P89 S93	H47-S51 VanDerWaalsContact O-CB 3.3Å; H47-S51 WeakPolarHBondContact O-CB 3.34Å; H47-S51 PolarHBondContact O-N 3Å; L48-S51 WeakPolarHBondContact O-CB 3.45Å; L48-S51 PolarHBondContact O-N 3.43Å; G49-S51 VanDerWaalsContact C-N 3.34Å; S51-L53 PolarHBondContact O-N 2.91Å; S51-L54 PolarHBondContact O-N 3.46Å; S51-L55 PolarHBondContact O-N 3.43Å; S51-P89 WeakPolarHBondContact O-CB 3.47Å; S51-P89 VanDerWaalsContact OG-C 3.29Å; S51-P89 WeakPolarHBondContact OG-CA 3.34Å; S51-P89 VanDerWaalsContact OG-CB 3.28Å; S51-P89 WeakPolarHBondContact OG-CB 3.5Å; S51-P89 PolarHBondContact OG-O 3.28Å; S51-S93 WeakPolarHBondContact CB-OG 3.38Å; S51-S93 PolarHBondContact OG-OG 2.93Å
52	D	98.4	Very high	97.2	Very high	1 Å²	1	22.7 Å²	22.7	1%	0.005	13%	0.126	C	C	.	.	H	α-helix	trans	-68.1	-34.2	-180	-66.5	-23.4	0	0	0	112.6	N23 L48 G49 A56 S93 V269 N272	N23-D52 VanDerWaalsContact OD1-CB 3.31Å; N23-D52 WeakPolarHBondContact OD1-CB 3.41Å; L48-D52 VanDerWaalsContact O-CG 3.3Å; L48-D52 PolarHBondContact O-N 3.04Å; G49-D52 PolarHBondContact O-N 3.3Å; D52-A56 VanDerWaalsContact O-CB 3.23Å; D52-A56 WeakPolarHBondContact O-CB 3.44Å; D52-A56 PolarHBondContact O-N 3.23Å; D52-S93 PolarHBondContact OD1-OG 2.74Å; D52-V269 HydrophobicContact CB-CB 4.43Å; D52-V269 HydrophobicContact CB-CG1 4.31Å; D52-V269 WeakPolarHBondContact O-CG1 3.35Å; D52-N272 VanDerWaalsContact CG-ND2 3.26Å; D52-N272 PolarHBondContact OD1-ND2 2.69Å; D52-N272 WeakPolarHBondContact OD2-CB 3.17Å; D52-N272 PolarHBondContact OD2-ND2 3.23Å
53	L	98.3	Very high	97.5	Very high	29 Å²	29	22.4 Å²	22.4	15%	0.152	12%	0.124	C	C	.	.	H	α-helix	trans	-64.8	-43.6	170.9	-83	-174.5	0	0	0	112	F20 N23 I27 G49 C50 S51 L55 A56 I57	F20-L53 HydrophobicContact CD2-CD2 3.87Å; F20-L53 HydrophobicContact CE2-CD2 4.11Å; F20-L53 HydrophobicContact CG-CD2 4.36Å; N23-L53 HydrophobicContact CB-CD2 3.66Å; N23-L53 HydrophobicContact CB-CG 3.75Å; I27-L53 HydrophobicContact CD1-CD1 3.36Å; I27-L53 HydrophobicContact CD1-CG 4Å; G49-L53 WeakPolarHBondContact O-CB 3.48Å; G49-L53 PolarHBondContact O-N 3.31Å; C50-L53 PolarHBondContact O-N 2.86Å; S51-L53 PolarHBondContact O-N 2.91Å; L53-L55 VanDerWaalsContact C-N 3.35Å; L53-A56 PolarHBondContact O-N 3.24Å; L53-I57 VanDerWaalsContact O-CG1 3.29Å; L53-I57 WeakPolarHBondContact O-CG1 3.3Å; L53-I57 PolarHBondContact O-N 2.88Å
54	L	98.3	Very high	97.6	Very high	73 Å²	73	25.6 Å²	25.6	38%	0.382	14%	0.143	S	C	.	.	H	α-helix	trans	-61.8	-45.8	177.8	-177	55.9	0	0	0	110.3	C50 S51 I57 T58 P89	C50-L54 WeakPolarHBondContact O-CB 3.43Å; C50-L54 PolarHBondContact O-N 3.37Å; S51-L54 PolarHBondContact O-N 3.46Å; L54-I57 PolarHBondContact O-N 3.18Å; L54-T58 WeakPolarHBondContact O-CG2 3.32Å; L54-T58 PolarHBondContact O-N 3.41Å; L54-P89 HydrophobicContact CB-CB 4.35Å; L54-P89 HydrophobicContact CB-CG 3.98Å; L54-P89 HydrophobicContact CD2-CG 3.56Å; L54-P89 HydrophobicContact CG-CG 3.67Å
55	L	98.6	Very high	97.6	Very high	0 Å²	0	24.9 Å²	24.9	0%	0	14%	0.141	C	C	.	.	H	α-helix	trans	-57.9	-49.7	171.9	175.8	54.7	0	0	0	111.2	S51 L53 I57 T58 L59 H86 P89 L90 V269	S51-L55 PolarHBondContact O-N 3.43Å; L53-L55 VanDerWaalsContact C-N 3.35Å; L55-I57 VanDerWaalsContact C-N 3.3Å; L55-I57 PolarHBondContact O-N 3.08Å; L55-T58 PolarHBondContact O-N 3.42Å; L55-T58 PolarHBondContact O-OG1 3.2Å; L55-L59 HydrophobicContact CD1-CD2 3.95Å; L55-L59 HydrophobicContact CG-CD2 4.33Å; L55-L59 WeakPolarHBondContact O-CG 3.31Å; L55-L59 PolarHBondContact O-N 2.89Å; L55-H86 WeakPolarHBondContact CD1-O 3.37Å; L55-P89 HydrophobicContact CB-CB 4.19Å; L55-L90 HydrophobicContact CD2-CB 4.23Å; L55-L90 HydrophobicContact CD2-CD1 3.94Å; L55-V269 HydrophobicContact CB-CG1 3.89Å; L55-V269 HydrophobicContact CD2-CG1 3.56Å; L55-V269 HydrophobicContact CG-CG1 3.59Å
56	A	98.6	Very high	97.6	Very high	0 Å²	0	25.6 Å²	25.6	0%	0	15%	0.147	C	C	.	.	H	α-helix	trans	-54.8	-44.4	-178.7	0	0	0	0	0	112	F16 F20 D52 L53 T58 L59 P60 V269	F16-A56 WeakPolarHBondContact CD2-O 3.44Å; F20-A56 HydrophobicContact CB-CB 4.48Å; D52-A56 VanDerWaalsContact O-CB 3.23Å; D52-A56 WeakPolarHBondContact O-CB 3.44Å; D52-A56 PolarHBondContact O-N 3.23Å; L53-A56 PolarHBondContact O-N 3.24Å; A56-T58 PolarHBondContact O-N 2.91Å; A56-L59 WeakPolarHBondContact O-CB 3.37Å; A56-L59 PolarHBondContact O-N 2.83Å; A56-P60 WeakPolarHBondContact O-CD 3.41Å; A56-V269 HydrophobicContact CB-CB 4.47Å; A56-V269 HydrophobicContact CB-CG1 4.34Å
57	I	98.4	Very high	97.5	Very high	102 Å²	102	28.2 Å²	28.2	52%	0.523	16%	0.161	S	C	.	.	H	α-helix	trans	-61.9	-27.8	179.4	-68.6	163.1	0	0	0	112.2	F20 L53 L54 L55 P60	F20-I57 HydrophobicContact CD2-CG1 4.19Å; F20-I57 HydrophobicContact CE2-CD1 4.24Å; F20-I57 HydrophobicContact CE2-CG1 3.87Å; L53-I57 VanDerWaalsContact O-CG1 3.29Å; L53-I57 WeakPolarHBondContact O-CG1 3.3Å; L53-I57 PolarHBondContact O-N 2.88Å; L54-I57 PolarHBondContact O-N 3.18Å; L55-I57 VanDerWaalsContact C-N 3.3Å; L55-I57 PolarHBondContact O-N 3.08Å; I57-P60 WeakPolarHBondContact O-CD 3.46Å
58	T	98.3	Very high	97.3	Very high	12 Å²	12	29 Å²	29	7%	0.074	17%	0.173	C	C	.	.	H	α-helix	trans	-81.2	-18.2	176.3	71.3	0	0	0	0	114	L54 L55 A56 L61 K62 F82 A85 H86	L54-T58 WeakPolarHBondContact O-CG2 3.32Å; L54-T58 PolarHBondContact O-N 3.41Å; L55-T58 PolarHBondContact O-N 3.42Å; L55-T58 PolarHBondContact O-OG1 3.2Å; A56-T58 PolarHBondContact O-N 2.91Å; T58-L61 PolarHBondContact O-N 2.97Å; T58-K62 PolarHBondContact O-N 3.11Å; T58-K62 VanDerWaalsContact O-N 3.17Å; T58-F82 HydrophobicContact CG2-CD2 4.47Å; T58-A85 HydrophobicContact CG2-CB 3.7Å; T58-A85 WeakPolarHBondContact CG2-O 3.47Å; T58-H86 HydrophobicContact CG2-CB 4.5Å; T58-H86 PolarHBondContact OG1-ND1 3.48Å
59	L	98.4	Very high	96.9	Very high	0 Å²	0	33.5 Å²	33.5	0%	0	20%	0.204	C	C	.	.	H	α-helix	trans	-62.9	-38.5	-174.1	-59.5	-174.5	0	0	0	114.4	Y12 A15 F16 L55 A56 L61 K62 A63 A266 V269	Y12-L59 HydrophobicContact CD1-CD2 4.26Å; A15-L59 HydrophobicContact CB-CD1 3.82Å; F16-L59 HydrophobicContact CB-CB 4.13Å; F16-L59 HydrophobicContact CB-CD1 4.46Å; L55-L59 HydrophobicContact CD1-CD2 3.95Å; L55-L59 HydrophobicContact CG-CD2 4.33Å; L55-L59 WeakPolarHBondContact O-CG 3.31Å; L55-L59 PolarHBondContact O-N 2.89Å; A56-L59 WeakPolarHBondContact O-CB 3.37Å; A56-L59 PolarHBondContact O-N 2.83Å; L59-L61 VanDerWaalsContact C-N 3.28Å; L59-L61 PolarHBondContact O-N 3.23Å; L59-K62 PolarHBondContact O-N 3.48Å; L59-A63 PolarHBondContact O-N 3.41Å; L59-A266 HydrophobicContact CD1-CB 4.37Å; L59-A266 HydrophobicContact CD2-CB 3.82Å; L59-V269 HydrophobicContact CD1-CG2 3.99Å
60	P	98.1	Very high	96.6	Very high	46 Å²	46	34.2 Å²	34.2	30%	0.299	21%	0.211	S	C	.	.	H	α-helix	trans	-57.9	-39.8	174.6	-27	36.2	0	0	0	113	F16 A56 I57 A63 V64	F16-P60 HydrophobicContact CB-CG 4.39Å; F16-P60 HydrophobicContact CD1-CG 3.95Å; F16-P60 HydrophobicContact CD2-CG 3.91Å; F16-P60 HydrophobicContact CE1-CG 4.17Å; F16-P60 HydrophobicContact CE2-CG 4.12Å; F16-P60 HydrophobicContact CG-CG 3.8Å; F16-P60 HydrophobicContact CZ-CG 4.25Å; A56-P60 WeakPolarHBondContact O-CD 3.41Å; I57-P60 WeakPolarHBondContact O-CD 3.46Å; P60-A63 WeakPolarHBondContact O-CB 3.07Å; P60-A63 PolarHBondContact O-N 2.69Å; P60-V64 WeakPolarHBondContact O-CG2 3.33Å; P60-V64 PolarHBondContact O-N 3.33Å
61	L	97.5	Very high	96.4	Very high	38 Å²	38	32.2 Å²	32.2	20%	0.199	20%	0.199	C	C	.	.	H	α-helix	trans	-66.6	-42.2	176.4	176.3	55.9	0	0	0	111.4	T58 L59 A63 V64 E65 W72 P73 L74 F82	T58-L61 PolarHBondContact O-N 2.97Å; L59-L61 VanDerWaalsContact C-N 3.28Å; L59-L61 PolarHBondContact O-N 3.23Å; L61-A63 PolarHBondContact O-N 3.38Å; L61-V64 PolarHBondContact O-N 2.86Å; L61-E65 PolarHBondContact O-N 3Å; L61-W72 HydrophobicContact CD1-CH2 4.47Å; L61-W72 HydrophobicContact CD1-CZ3 4.47Å; L61-W72 HydrophobicContact CD2-CH2 3.83Å; L61-W72 HydrophobicContact CD2-CZ3 4.34Å; L61-W72 HydrophobicContact CG-CH2 4.31Å; L61-W72 HydrophobicContact CG-CZ3 4.36Å; L61-P73 HydrophobicContact CD1-CG 3.68Å; L61-L74 HydrophobicContact CD1-CD1 3.59Å; L61-L74 HydrophobicContact CD1-CG 3.75Å; L61-L74 HydrophobicContact CD2-CD1 3.42Å; L61-L74 VanDerWaalsContact CD2-CD1 3.42Å; L61-L74 HydrophobicContact CD2-CG 4.46Å; L61-L74 HydrophobicContact CG-CD1 4.17Å; L61-F82 HydrophobicContact CB-CD2 4.46Å; L61-F82 HydrophobicContact CB-CE2 4.11Å; L61-F82 HydrophobicContact CD2-CB 4.32Å; L61-F82 HydrophobicContact CD2-CD2 3.42Å; L61-F82 VanDerWaalsContact CD2-CD2 3.42Å; L61-F82 HydrophobicContact CD2-CE2 3.86Å; L61-F82 HydrophobicContact CD2-CG 3.98Å; L61-F82 HydrophobicContact CG-CD2 4.01Å; L61-F82 HydrophobicContact CG-CE2 3.92Å
62	K	96.9	Very high	96.3	Very high	8 Å²	8	32.7 Å²	32.7	4%	0.035	20%	0.201	C	C	.	.	H	α-helix	trans	-62.7	-32.5	173	-165.1	51.3	164.8	-178.2	0	112.3	Y12 T58 L59 E65 A66 F82 E172	Y12-K62 HydrophobicContact CD1-CB 4.47Å; Y12-K62 HydrophobicContact CD1-CG 4.28Å; Y12-K62 HydrophobicContact CD2-CG 4.36Å; Y12-K62 HydrophobicContact CE1-CB 4.44Å; Y12-K62 HydrophobicContact CE1-CG 3.79Å; Y12-K62 HydrophobicContact CE2-CG 3.9Å; T58-K62 PolarHBondContact O-N 3.11Å; T58-K62 VanDerWaalsContact O-N 3.17Å; L59-K62 PolarHBondContact O-N 3.48Å; K62-E65 WeakPolarHBondContact CD-OE2 3.37Å; K62-E65 IonicContact NZ-OE1 2.85Å; K62-E65 PolarHBondContact NZ-OE1 3.34Å; K62-E65 IonicContact NZ-OE2 3.53Å; K62-E65 PolarHBondContact NZ-OE2 3.11Å; K62-A66 WeakPolarHBondContact O-CB 3.24Å; K62-A66 PolarHBondContact O-N 3.34Å; K62-F82 HydrophobicContact CB-CZ 4Å; K62-F82 HydrophobicContact CD-CE1 4.42Å; K62-F82 HydrophobicContact CD-CZ 4.01Å; K62-F82 HydrophobicContact CG-CZ 4.46Å; K62-E172 IonicContact NZ-OE1 2.72Å
63	A	97.4	Very high	96	Very high	0 Å²	0	35.4 Å²	35.4	0%	0	22%	0.219	C	C	.	.	H	α-helix	trans	-65.5	-46.6	174.4	0	0	0	0	0	111.4	F9 V13 L59 P60 L61 A66 L67	F9-A63 HydrophobicContact CD2-CB 3.7Å; F9-A63 WeakPolarHBondContact CD2-O 3.38Å; F9-A63 HydrophobicContact CE2-CB 4.05Å; F9-A63 HydrophobicContact CG-CB 4.39Å; V13-A63 HydrophobicContact CG2-CB 3.93Å; L59-A63 PolarHBondContact O-N 3.41Å; P60-A63 WeakPolarHBondContact O-CB 3.07Å; P60-A63 PolarHBondContact O-N 2.69Å; L61-A63 PolarHBondContact O-N 3.38Å; A63-A66 WeakPolarHBondContact O-CB 3.31Å; A63-A66 PolarHBondContact O-N 2.78Å; A63-L67 PolarHBondContact O-N 3.13Å
64	V	96.9	Very high	95.8	Very high	68 Å²	68	37.5 Å²	37.5	41%	0.412	23%	0.23	S	C	.	.	H	α-helix	trans	-62.5	-42.3	176.6	176.5	0	0	0	0	111.1	P60 L61 A66 L67 A68 P73	P60-V64 WeakPolarHBondContact O-CG2 3.33Å; P60-V64 PolarHBondContact O-N 3.33Å; L61-V64 PolarHBondContact O-N 2.86Å; V64-A66 VanDerWaalsContact C-N 3.3Å; V64-A66 PolarHBondContact O-N 3.21Å; V64-L67 PolarHBondContact O-N 3.32Å; V64-A68 WeakPolarHBondContact O-CB 3.23Å; V64-A68 PolarHBondContact O-N 3.21Å; V64-P73 HydrophobicContact CB-CG 4.41Å; V64-P73 HydrophobicContact CG1-CB 3.8Å; V64-P73 HydrophobicContact CG1-CG 3.86Å
65	E	95.2	Very high	95.7	Very high	7 Å²	7	37.6 Å²	37.6	3%	0.033	24%	0.235	C	C	.	.	H	α-helix	trans	-57.2	-43.7	173	-171.8	-156.6	133	0	0	111.4	L61 K62 L67 A68 S69 G70	L61-E65 PolarHBondContact O-N 3Å; K62-E65 WeakPolarHBondContact CD-OE2 3.37Å; K62-E65 IonicContact NZ-OE1 2.85Å; K62-E65 PolarHBondContact NZ-OE1 3.34Å; K62-E65 IonicContact NZ-OE2 3.53Å; K62-E65 PolarHBondContact NZ-OE2 3.11Å; E65-L67 PolarHBondContact O-N 3.4Å; E65-A68 CarbonylContact O-C 3.49Å; E65-A68 PolarHBondContact O-N 2.79Å; E65-S69 PolarHBondContact O-N 3.18Å; E65-G70 PolarHBondContact O-N 2.86Å
66	A	93.7	Very high	95.4	Very high	21 Å²	21	40.5 Å²	40.5	17%	0.174	25%	0.25	C	S	.	.	H	α-helix	trans	-64.3	-39.5	177.2	0	0	0	0	0	112.4	P5 Y12 K62 A63 V64 A68 S69	P5-A66 WeakPolarHBondContact CB-O 3.31Å; Y12-A66 HydrophobicContact CD2-CB 4.39Å; Y12-A66 HydrophobicContact CE2-CB 4.34Å; K62-A66 WeakPolarHBondContact O-CB 3.24Å; K62-A66 PolarHBondContact O-N 3.34Å; A63-A66 WeakPolarHBondContact O-CB 3.31Å; A63-A66 PolarHBondContact O-N 2.78Å; V64-A66 VanDerWaalsContact C-N 3.3Å; V64-A66 PolarHBondContact O-N 3.21Å; A66-A68 VanDerWaalsContact C-N 3.33Å; A66-S69 PolarHBondContact O-N 2.9Å; A66-S69 VanDerWaalsContact O-N 3.15Å
67	L	94.5	Very high	95	Very high	84 Å²	84	44.6 Å²	44.6	44%	0.44	28%	0.277	S	S	.	.	H	α-helix	trans	-67.2	-35.5	176.2	-168.3	64.1	0	0	0	111.8	F9 A63 V64 E65 S69	F9-L67 HydrophobicContact CB-CB 4.48Å; F9-L67 HydrophobicContact CB-CD1 4.48Å; F9-L67 HydrophobicContact CD2-CB 4.06Å; F9-L67 HydrophobicContact CD2-CD2 4.15Å; F9-L67 HydrophobicContact CE2-CD2 4.34Å; A63-L67 PolarHBondContact O-N 3.13Å; V64-L67 PolarHBondContact O-N 3.32Å; E65-L67 PolarHBondContact O-N 3.4Å; L67-S69 PolarHBondContact O-N 3.38Å
68	A	93.3	Very high	94.8	Very high	44 Å²	44	45.2 Å²	45.2	36%	0.364	28%	0.276	S	S	.	.	T	Hydrogen-bonded Turn	trans	-77.4	15.4	172.7	0	0	0	0	0	113.4	V64 E65 A66 G70 A71	V64-A68 WeakPolarHBondContact O-CB 3.23Å; V64-A68 PolarHBondContact O-N 3.21Å; E65-A68 CarbonylContact O-C 3.49Å; E65-A68 PolarHBondContact O-N 2.79Å; A66-A68 VanDerWaalsContact C-N 3.33Å; A68-G70 PolarHBondContact O-N 3.29Å; A68-G70 VanDerWaalsContact O-N 3.17Å; A68-A71 HydrophobicContact CB-CB 4.15Å; A68-A71 WeakPolarHBondContact O-CB 3.34Å; A68-A71 PolarHBondContact O-N 3.44Å; A68-A71 VanDerWaalsContact O-N 3.11Å
69	S	90.4	Very high	94.7	Very high	97 Å²	97	44.7 Å²	44.7	68%	0.678	27%	0.272	S	S	*	.	T	Hydrogen-bonded Turn	trans	56	31.5	178.7	-58.2	0	0	0	0	114.2	E65 A66 L67	E65-S69 PolarHBondContact O-N 3.18Å; A66-S69 PolarHBondContact O-N 2.9Å; A66-S69 VanDerWaalsContact O-N 3.15Å; L67-S69 PolarHBondContact O-N 3.38Å
70	G	90.9	Very high	94.4	Very high	19 Å²	19	45.9 Å²	45.9	20%	0.196	28%	0.281	C	S	.	.	T	Hydrogen-bonded Turn	trans	96.2	-4.1	179.2	0	0	0	0	0	114.8	E65 A68	E65-G70 PolarHBondContact O-N 2.86Å; A68-G70 PolarHBondContact O-N 3.29Å; A68-G70 VanDerWaalsContact O-N 3.17Å
71	A	93.7	Very high	94.3	Very high	27 Å²	27	47.9 Å²	47.9	22%	0.223	29%	0.292	C	S	.	.			trans	-69.6	137.7	173.2	0	0	0	0	0	110.9	A68 P73 P168	A68-A71 HydrophobicContact CB-CB 4.15Å; A68-A71 WeakPolarHBondContact O-CB 3.34Å; A68-A71 PolarHBondContact O-N 3.44Å; A68-A71 VanDerWaalsContact O-N 3.11Å; A71-P73 WeakPolarHBondContact O-CD 3.23Å; A71-P168 WeakPolarHBondContact CA-O 3.48Å
72	W	95.8	Very high	94.3	Very high	11 Å²	11	46.6 Å²	46.6	4%	0.042	29%	0.285	C	S	.	.			trans	-75.4	116.9	-179.9	-178.7	-115.4	0	0	0	110.6	L61 L74 P75 F78 C79 F82 I160 P168 C170	L61-W72 HydrophobicContact CD1-CH2 4.47Å; L61-W72 HydrophobicContact CD1-CZ3 4.47Å; L61-W72 HydrophobicContact CD2-CH2 3.83Å; L61-W72 HydrophobicContact CD2-CZ3 4.34Å; L61-W72 HydrophobicContact CG-CH2 4.31Å; L61-W72 HydrophobicContact CG-CZ3 4.36Å; W72-L74 HydrophobicContact CH2-CD1 4.31Å; W72-L74 HydrophobicContact CZ2-CB 3.69Å; W72-L74 HydrophobicContact CZ2-CD1 4.09Å; W72-L74 HydrophobicContact CZ2-CG 4.36Å; W72-L74 PolarHBondContact NE1-O 2.93Å; W72-P75 PolarHBondContact NE1-O 3.32Å; W72-P75 VanDerWaalsContact NE1-O 3.16Å; W72-F78 HydrophobicContact CZ2-CB 4.09Å; W72-C79 HydrophobicContact CD2-CB 4.48Å; W72-C79 HydrophobicContact CZ2-CB 4.14Å; W72-F82 HydrophobicContact CH2-CB 3.53Å; W72-F82 AromaticContact CH2-CD1 3.7Å; W72-F82 HydrophobicContact CH2-CD1 3.7Å; W72-F82 HydrophobicContact CH2-CD2 4.42Å; W72-F82 AromaticContact CH2-CG 3.62Å; W72-F82 HydrophobicContact CH2-CG 3.62Å; W72-F82 HydrophobicContact CZ2-CB 4.37Å; W72-F82 HydrophobicContact CZ3-CB 4.29Å; W72-F82 AromaticContact CZ3-CD1 3.55Å; W72-F82 HydrophobicContact CZ3-CD1 3.55Å; W72-F82 HydrophobicContact CZ3-CE1 4.01Å; W72-F82 AromaticContact CZ3-CG 3.93Å; W72-F82 HydrophobicContact CZ3-CG 3.93Å; W72-I160 HydrophobicContact CB-CD1 4.38Å; W72-I160 HydrophobicContact CG-CD1 4.01Å; W72-P168 HydrophobicContact CB-CB 4.44Å; W72-P168 WeakPolarHBondContact CB-O 3.35Å; W72-P168 PolarHBondContact N-O 3.49Å; W72-C170 HydrophobicContact CB-CB 4.24Å; W72-C170 HydrophobicContact CD2-CB 3.68Å; W72-C170 HydrophobicContact CE3-CB 3.42Å; W72-C170 VanDerWaalsContact CE3-CB 3.42Å; W72-C170 HydrophobicContact CG-CB 4.05Å; W72-C170 HydrophobicContact CZ3-CB 4.05Å
73	P	93.2	Very high	94.2	Very high	58 Å²	58	46.6 Å²	46.6	38%	0.377	29%	0.286	S	S	.	.			trans	-89.9	-5.1	-170.4	35.7	-36.8	0	0	0	114.3	L61 V64 A71	L61-P73 HydrophobicContact CD1-CG 3.68Å; V64-P73 HydrophobicContact CB-CG 4.41Å; V64-P73 HydrophobicContact CG1-CB 3.8Å; V64-P73 HydrophobicContact CG1-CG 3.86Å; A71-P73 WeakPolarHBondContact O-CD 3.23Å
74	L	94.3	Very high	94.1	Very high	73 Å²	73	49.2 Å²	49.2	38%	0.382	30%	0.299	S	S	.	.	S	Bend	trans	-109	169.7	-177.3	-73.5	-177	0	0	0	111.8	L61 W72 F78	L61-L74 HydrophobicContact CD1-CD1 3.59Å; L61-L74 HydrophobicContact CD1-CG 3.75Å; L61-L74 HydrophobicContact CD2-CD1 3.42Å; L61-L74 VanDerWaalsContact CD2-CD1 3.42Å; L61-L74 HydrophobicContact CD2-CG 4.46Å; L61-L74 HydrophobicContact CG-CD1 4.17Å; W72-L74 HydrophobicContact CH2-CD1 4.31Å; W72-L74 HydrophobicContact CZ2-CB 3.69Å; W72-L74 HydrophobicContact CZ2-CD1 4.09Å; W72-L74 HydrophobicContact CZ2-CG 4.36Å; W72-L74 PolarHBondContact NE1-O 2.93Å; L74-F78 HydrophobicContact CB-CB 4.44Å; L74-F78 HydrophobicContact CD1-CB 4.42Å
75	P	94.6	Very high	94.2	Very high	75 Å²	75	47 Å²	47	49%	0.487	29%	0.289	S	S	.	.			trans	-56.1	146.2	170.4	-22.7	32	0	0	0	112	W72 P77 F78	W72-P75 PolarHBondContact NE1-O 3.32Å; W72-P75 VanDerWaalsContact NE1-O 3.16Å; P75-P77 VanDerWaalsContact C-CD 3.43Å; P75-F78 HydrophobicContact CB-CD2 3.83Å; P75-F78 HydrophobicContact CB-CE2 4.13Å; P75-F78 HydrophobicContact CG-CD2 3.97Å; P75-F78 HydrophobicContact CG-CE2 4.04Å; P75-F78 PolarHBondContact O-N 3.48Å; P75-F78 VanDerWaalsContact O-N 3.14Å
76	L	93.4	Very high	94.3	Very high	61 Å²	61	46.9 Å²	46.9	32%	0.319	29%	0.288	S	S	.	.	T	Hydrogen-bonded Turn	trans	-55.1	-40.5	-170.5	-53.9	-176.6	0	0	0	114.9	F78 C79 S157 I160 P168	L76-F78 PolarHBondContact O-N 2.92Å; L76-C79 PolarHBondContact O-N 3.46Å; L76-S157 WeakPolarHBondContact CB-OG 3.4Å; L76-I160 HydrophobicContact CB-CG1 4.2Å; L76-I160 HydrophobicContact CD2-CD1 4.18Å; L76-I160 HydrophobicContact CD2-CG1 4.26Å; L76-I160 HydrophobicContact CD2-CG2 4.2Å; L76-P168 HydrophobicContact CD2-CB 3.8Å; L76-P168 HydrophobicContact CD2-CG 4.22Å
77	P	90.1	Very high	94.5	Very high	86 Å²	86	46.2 Å²	46.2	56%	0.558	28%	0.281	S	S	*	.	T	Hydrogen-bonded Turn	trans	-63.3	-24.1	-178.9	-23.9	35.5	0	0	0	114.2	P75 C79 S80	P75-P77 VanDerWaalsContact C-CD 3.43Å; P77-C79 PolarHBondContact O-N 2.91Å; P77-S80 PolarHBondContact O-OG 3.4Å
78	F	94.4	Very high	94.6	Very high	115 Å²	115	42.3 Å²	42.3	50%	0.504	26%	0.261	S	S	.	.	H	α-helix	trans	-74.3	-12.1	-178.3	-70.6	-71.1	0	0	0	113.8	W72 L74 P75 L76 V81 F82	W72-F78 HydrophobicContact CZ2-CB 4.09Å; L74-F78 HydrophobicContact CB-CB 4.44Å; L74-F78 HydrophobicContact CD1-CB 4.42Å; P75-F78 HydrophobicContact CB-CD2 3.83Å; P75-F78 HydrophobicContact CB-CE2 4.13Å; P75-F78 HydrophobicContact CG-CD2 3.97Å; P75-F78 HydrophobicContact CG-CE2 4.04Å; P75-F78 PolarHBondContact O-N 3.48Å; P75-F78 VanDerWaalsContact O-N 3.14Å; L76-F78 PolarHBondContact O-N 2.92Å; F78-V81 PolarHBondContact O-N 2.94Å; F78-F82 WeakPolarHBondContact O-CB 3.19Å; F78-F82 PolarHBondContact O-N 2.84Å
79	C	95.2	Very high	94.9	Very high	0 Å²	0	40.2 Å²	40.2	0%	0	24%	0.244	C	C	.	.	H	α-helix	trans	-60	-51.1	179.8	168.6	0	0	0	0	112.1	W72 L76 P77 V81 F82 V83 G159 I160 C170	W72-C79 HydrophobicContact CD2-CB 4.48Å; W72-C79 HydrophobicContact CZ2-CB 4.14Å; L76-C79 PolarHBondContact O-N 3.46Å; P77-C79 PolarHBondContact O-N 2.91Å; C79-V81 VanDerWaalsContact C-N 3.33Å; C79-V81 PolarHBondContact O-N 3.35Å; C79-F82 WeakPolarHBondContact O-CB 3.48Å; C79-F82 PolarHBondContact O-N 3.14Å; C79-V83 WeakPolarHBondContact O-CG2 3.45Å; C79-V83 PolarHBondContact O-N 3.2Å; C79-G159 VanDerWaalsContact SG-C 3.55Å; C79-G159 PolarHBondContact SG-O 3.18Å; C79-G159 VanDerWaalsContact SG-O 3.37Å; C79-I160 HydrophobicContact CB-CD1 3.51Å; C79-I160 HydrophobicContact CB-CG1 3.87Å; C79-C170 WeakPolarHBondContact CA-SG 3.19Å; C79-C170 HydrophobicContact CB-CB 3.87Å; C79-C170 WeakPolarHBondContact CB-SG 3.29Å; C79-C170 WeakPolarHBondContact SG-CA 3.48Å; C79-C170 WeakPolarHBondContact SG-CB 3.21Å; C79-C170 CovalentContact SG-SG 2.03Å; C79-C170 PolarHBondContact SG-SG 2.98Å
80	S	93.6	Very high	95.2	Very high	25 Å²	25	35.8 Å²	35.8	18%	0.175	21%	0.212	C	C	.	.	H	α-helix	trans	-60.2	-41.2	179.8	61.7	0	0	0	0	113	P77 V83 L84	P77-S80 PolarHBondContact O-OG 3.4Å; S80-V83 PolarHBondContact O-N 3.49Å; S80-L84 PolarHBondContact O-N 2.84Å
81	V	95.4	Very high	95.6	Very high	88 Å²	88	35 Å²	35	53%	0.533	20%	0.204	S	C	.	.	H	α-helix	trans	-62.8	-45.8	176.1	-179.6	0	0	0	0	110.5	F78 C79 L84 A85	F78-V81 PolarHBondContact O-N 2.94Å; C79-V81 VanDerWaalsContact C-N 3.33Å; C79-V81 PolarHBondContact O-N 3.35Å; V81-L84 PolarHBondContact O-N 2.83Å; V81-A85 VanDerWaalsContact O-CB 3.26Å; V81-A85 WeakPolarHBondContact O-CB 3.33Å; V81-A85 PolarHBondContact O-N 3.45Å
82	F	96.8	Very high	95.8	Very high	12 Å²	12	33.8 Å²	33.8	5%	0.053	19%	0.193	C	C	.	.	H	α-helix	trans	-62	-44.9	176.4	168.6	-104.8	0	0	0	112.2	T58 L61 K62 W72 F78 C79 L84 A85 H86	T58-F82 HydrophobicContact CG2-CD2 4.47Å; L61-F82 HydrophobicContact CB-CD2 4.46Å; L61-F82 HydrophobicContact CB-CE2 4.11Å; L61-F82 HydrophobicContact CD2-CB 4.32Å; L61-F82 HydrophobicContact CD2-CD2 3.42Å; L61-F82 VanDerWaalsContact CD2-CD2 3.42Å; L61-F82 HydrophobicContact CD2-CE2 3.86Å; L61-F82 HydrophobicContact CD2-CG 3.98Å; L61-F82 HydrophobicContact CG-CD2 4.01Å; L61-F82 HydrophobicContact CG-CE2 3.92Å; K62-F82 HydrophobicContact CB-CZ 4Å; K62-F82 HydrophobicContact CD-CE1 4.42Å; K62-F82 HydrophobicContact CD-CZ 4.01Å; K62-F82 HydrophobicContact CG-CZ 4.46Å; W72-F82 HydrophobicContact CH2-CB 3.53Å; W72-F82 AromaticContact CH2-CD1 3.7Å; W72-F82 HydrophobicContact CH2-CD1 3.7Å; W72-F82 HydrophobicContact CH2-CD2 4.42Å; W72-F82 AromaticContact CH2-CG 3.62Å; W72-F82 HydrophobicContact CH2-CG 3.62Å; W72-F82 HydrophobicContact CZ2-CB 4.37Å; W72-F82 HydrophobicContact CZ3-CB 4.29Å; W72-F82 AromaticContact CZ3-CD1 3.55Å; W72-F82 HydrophobicContact CZ3-CD1 3.55Å; W72-F82 HydrophobicContact CZ3-CE1 4.01Å; W72-F82 AromaticContact CZ3-CG 3.93Å; W72-F82 HydrophobicContact CZ3-CG 3.93Å; F78-F82 WeakPolarHBondContact O-CB 3.19Å; F78-F82 PolarHBondContact O-N 2.84Å; C79-F82 WeakPolarHBondContact O-CB 3.48Å; C79-F82 PolarHBondContact O-N 3.14Å; F82-L84 VanDerWaalsContact C-N 3.33Å; F82-L84 PolarHBondContact O-N 2.8Å; F82-A85 CarbonylContact O-C 3.55Å; F82-A85 PolarHBondContact O-N 3.39Å; F82-H86 HydrophobicContact CE2-CB 4.22Å; F82-H86 HydrophobicContact CZ-CB 4.22Å; F82-H86 WeakPolarHBondContact O-CB 3.5Å; F82-H86 PolarHBondContact O-N 3.47Å
83	V	95.3	Very high	95.9	Very high	8 Å²	8	33.3 Å²	33.3	5%	0.048	19%	0.191	C	C	.	.	H	α-helix	trans	-56.8	-48.3	177.9	166.5	0	0	0	0	110.4	C79 S80 H86 F87 L142 L171	C79-V83 WeakPolarHBondContact O-CG2 3.45Å; C79-V83 PolarHBondContact O-N 3.2Å; S80-V83 PolarHBondContact O-N 3.49Å; V83-H86 PolarHBondContact O-N 3.5Å; V83-F87 HydrophobicContact CG1-CD2 4.03Å; V83-F87 WeakPolarHBondContact O-CB 3.44Å; V83-F87 WeakPolarHBondContact O-CD2 3.27Å; V83-F87 PolarHBondContact O-N 2.86Å; V83-L142 HydrophobicContact CG1-CD1 4.47Å; V83-L142 HydrophobicContact CG1-CD2 4.27Å; V83-L171 HydrophobicContact CG1-CD1 4.49Å; V83-L171 HydrophobicContact CG1-CD2 3.81Å; V83-L171 HydrophobicContact CG2-CB 3.99Å; V83-L171 HydrophobicContact CG2-CD1 4.42Å; V83-L171 HydrophobicContact CG2-CD2 3.98Å; V83-L171 HydrophobicContact CG2-CG 4.36Å
84	L	96.4	Very high	96.1	Very high	54 Å²	54	30.6 Å²	30.6	28%	0.283	17%	0.174	S	C	.	.	H	α-helix	trans	-65.5	-44.5	177	-69.9	174.7	0	0	0	111.8	S80 V81 F82 H86 A88 P89 M138 L142	S80-L84 PolarHBondContact O-N 2.84Å; V81-L84 PolarHBondContact O-N 2.83Å; F82-L84 VanDerWaalsContact C-N 3.33Å; F82-L84 PolarHBondContact O-N 2.8Å; L84-H86 VanDerWaalsContact C-N 3.27Å; L84-H86 PolarHBondContact O-N 2.96Å; L84-A88 WeakPolarHBondContact O-CB 3.4Å; L84-A88 PolarHBondContact O-N 3.24Å; L84-P89 WeakPolarHBondContact O-CD 3.08Å; L84-M138 HydrophobicContact CD2-CB 4Å; L84-L142 HydrophobicContact CG-CD2 4.41Å
85	A	97.3	Very high	96.3	Very high	23 Å²	23	27.7 Å²	27.7	19%	0.19	16%	0.162	C	C	.	.	H	α-helix	trans	-67.6	-23.8	179.7	0	0	0	0	0	113.7	T58 V81 F82 P89	T58-A85 HydrophobicContact CG2-CB 3.7Å; T58-A85 WeakPolarHBondContact CG2-O 3.47Å; V81-A85 VanDerWaalsContact O-CB 3.26Å; V81-A85 WeakPolarHBondContact O-CB 3.33Å; V81-A85 PolarHBondContact O-N 3.45Å; F82-A85 CarbonylContact O-C 3.55Å; F82-A85 PolarHBondContact O-N 3.39Å; A85-P89 VanDerWaalsContact O-CD 3.24Å; A85-P89 WeakPolarHBondContact O-CD 3.2Å; A85-P89 WeakPolarHBondContact O-CG 3.39Å
86	H	97.7	Very high	96.4	Very high	3 Å²	3	24.1 Å²	24.1	1%	0.014	14%	0.138	C	C	.	.	H	α-helix	trans	-90.6	-51.6	178.6	-168.2	83.6	0	0	0	111.3	L55 T58 F82 V83 L84	L55-H86 WeakPolarHBondContact CD1-O 3.37Å; T58-H86 HydrophobicContact CG2-CB 4.5Å; T58-H86 PolarHBondContact OG1-ND1 3.48Å; F82-H86 HydrophobicContact CE2-CB 4.22Å; F82-H86 HydrophobicContact CZ-CB 4.22Å; F82-H86 WeakPolarHBondContact O-CB 3.5Å; F82-H86 PolarHBondContact O-N 3.47Å; V83-H86 PolarHBondContact O-N 3.5Å; L84-H86 VanDerWaalsContact C-N 3.27Å; L84-H86 PolarHBondContact O-N 2.96Å
87	F	97.3	Very high	96.5	Very high	7 Å²	7	21.3 Å²	21.3	3%	0.031	12%	0.124	C	C	.	.	H	α-helix	trans	-86.5	-35.5	-172.3	-69	-76.1	0	0	0	113.6	V83 L90 Y91 M138 L171 Y240 L262	V83-F87 HydrophobicContact CG1-CD2 4.03Å; V83-F87 WeakPolarHBondContact O-CB 3.44Å; V83-F87 WeakPolarHBondContact O-CD2 3.27Å; V83-F87 PolarHBondContact O-N 2.86Å; F87-L90 HydrophobicContact CD1-CD2 4.3Å; F87-L90 WeakPolarHBondContact O-CB 3.47Å; F87-L90 PolarHBondContact O-N 2.96Å; F87-Y91 WeakPolarHBondContact O-CD2 3.41Å; F87-Y91 PolarHBondContact O-N 3.1Å; F87-Y91 VanDerWaalsContact O-N 3.11Å; F87-M138 HydrophobicContact CB-CE 3.76Å; F87-M138 HydrophobicContact CB-SD 4.19Å; F87-L171 HydrophobicContact CE2-CD2 4.16Å; F87-Y240 HydrophobicContact CD1-CE1 4.38Å; F87-Y240 HydrophobicContact CE1-CE1 4.19Å; F87-Y240 HydrophobicContact CE1-CE2 4.42Å; F87-Y240 AromaticContact CE1-CZ 3.72Å; F87-Y240 WeakPolarHBondContact CE1-OH 3.39Å; F87-L262 HydrophobicContact CE1-CD2 3.52Å; F87-L262 HydrophobicContact CZ-CD2 3.68Å
88	A	98.2	Very high	96.9	Very high	2 Å²	2	17.4 Å²	17.4	2%	0.017	10%	0.099	C	C	.	.	H	α-helix	trans	-61.1	-45.3	179.5	0	0	0	0	0	111.6	L84 L90 Y91 A92 V134 L135	L84-A88 WeakPolarHBondContact O-CB 3.4Å; L84-A88 PolarHBondContact O-N 3.24Å; A88-L90 PolarHBondContact O-N 3.36Å; A88-Y91 PolarHBondContact O-N 2.88Å; A88-A92 VanDerWaalsContact O-CB 3.24Å; A88-A92 WeakPolarHBondContact O-CB 3.39Å; A88-A92 PolarHBondContact O-N 3.36Å; A88-V134 HydrophobicContact CB-CG1 3.76Å; A88-V134 WeakPolarHBondContact O-CG1 3.43Å; A88-L135 HydrophobicContact CB-CD2 3.77Å
89	P	98.4	Very high	96.9	Very high	1 Å²	1	12.6 Å²	12.6	1%	0.006	8%	0.081	C	C	.	.	H	α-helix	trans	-69.1	-35.2	177.8	-20.1	35.1	0	0	0	112.8	S51 L54 L55 L84 A85 Y91 A92 S93 W131	S51-P89 WeakPolarHBondContact O-CB 3.47Å; S51-P89 VanDerWaalsContact OG-C 3.29Å; S51-P89 WeakPolarHBondContact OG-CA 3.34Å; S51-P89 VanDerWaalsContact OG-CB 3.28Å; S51-P89 WeakPolarHBondContact OG-CB 3.5Å; S51-P89 PolarHBondContact OG-O 3.28Å; L54-P89 HydrophobicContact CB-CB 4.35Å; L54-P89 HydrophobicContact CB-CG 3.98Å; L54-P89 HydrophobicContact CD2-CG 3.56Å; L54-P89 HydrophobicContact CG-CG 3.67Å; L55-P89 HydrophobicContact CB-CB 4.19Å; L84-P89 WeakPolarHBondContact O-CD 3.08Å; A85-P89 VanDerWaalsContact O-CD 3.24Å; A85-P89 WeakPolarHBondContact O-CD 3.2Å; A85-P89 WeakPolarHBondContact O-CG 3.39Å; P89-Y91 VanDerWaalsContact C-N 3.29Å; P89-Y91 PolarHBondContact O-N 3.06Å; P89-A92 PolarHBondContact O-N 3.31Å; P89-S93 WeakPolarHBondContact O-CB 3.44Å; P89-S93 PolarHBondContact O-N 2.78Å; P89-S93 PolarHBondContact O-OG 2.92Å; P89-W131 HydrophobicContact CB-CH2 4.34Å; P89-W131 HydrophobicContact CG-CH2 4.35Å
90	L	97.6	Very high	96.8	Very high	4 Å²	4	12.6 Å²	12.6	2%	0.021	8%	0.081	C	C	.	.	H	α-helix	trans	-54	-47.8	174.1	-179.7	67.2	0	0	0	111.5	L55 F87 A88 L237 Y240 G265	L55-L90 HydrophobicContact CD2-CB 4.23Å; L55-L90 HydrophobicContact CD2-CD1 3.94Å; F87-L90 HydrophobicContact CD1-CD2 4.3Å; F87-L90 WeakPolarHBondContact O-CB 3.47Å; F87-L90 PolarHBondContact O-N 2.96Å; A88-L90 PolarHBondContact O-N 3.36Å; L90-L237 HydrophobicContact CD1-CD1 3.99Å; L90-L237 HydrophobicContact CD1-CG 4.04Å; L90-L237 HydrophobicContact CG-CG 4.44Å; L90-Y240 HydrophobicContact CD2-CD1 4.32Å; L90-Y240 HydrophobicContact CD2-CE1 4.48Å; L90-G265 WeakPolarHBondContact CD1-O 3.46Å
91	Y	98.4	Very high	96.8	Very high	3 Å²	3	11.6 Å²	11.6	1%	0.012	7%	0.074	C	C	.	.	H	α-helix	trans	-77.6	-37.5	179.6	-79.5	-72.8	0	0	0	113.5	F87 A88 P89 S93 G94 G95 M138 F186 L190 F191 Y240 N241	F87-Y91 WeakPolarHBondContact O-CD2 3.41Å; F87-Y91 PolarHBondContact O-N 3.1Å; F87-Y91 VanDerWaalsContact O-N 3.11Å; A88-Y91 PolarHBondContact O-N 2.88Å; P89-Y91 VanDerWaalsContact C-N 3.29Å; P89-Y91 PolarHBondContact O-N 3.06Å; Y91-S93 VanDerWaalsContact C-N 3.28Å; Y91-S93 PolarHBondContact O-N 2.99Å; Y91-G94 PolarHBondContact O-N 3.08Å; Y91-G94 VanDerWaalsContact O-N 3.1Å; Y91-G95 PolarHBondContact O-N 2.84Å; Y91-M138 HydrophobicContact CD2-CE 3.03Å; Y91-M138 HydrophobicContact CE2-CE 3.36Å; Y91-M138 HydrophobicContact CG-CE 3.99Å; Y91-F186 HydrophobicContact CE2-CB 4.32Å; Y91-L190 HydrophobicContact CD1-CB 3.27Å; Y91-L190 HydrophobicContact CD1-CD1 4.27Å; Y91-L190 HydrophobicContact CD1-CG 4.41Å; Y91-L190 HydrophobicContact CD2-CD1 4.48Å; Y91-L190 HydrophobicContact CE1-CB 3.9Å; Y91-L190 HydrophobicContact CG-CB 3.8Å; Y91-L190 HydrophobicContact CG-CD1 4.02Å; Y91-F191 HydrophobicContact CE1-CB 4.19Å; Y91-Y240 HydrophobicContact CE2-CE1 4.23Å; Y91-Y240 WeakPolarHBondContact OH-CE1 3.39Å; Y91-N241 VanDerWaalsContact CE1-OD1 3.3Å; Y91-N241 WeakPolarHBondContact CE1-OD1 3.3Å; Y91-N241 PolarHBondContact OH-OD1 2.73Å
92	A	98.6	Very high	96.7	Very high	0 Å²	0	8.8 Å²	8.8	0%	0	6%	0.059	C	C	.	.	H	α-helix	trans	-60.6	-38.9	175.1	0	0	0	0	0	111.4	A88 P89 G94 G95 F96 I130 W131 V134	A88-A92 VanDerWaalsContact O-CB 3.24Å; A88-A92 WeakPolarHBondContact O-CB 3.39Å; A88-A92 PolarHBondContact O-N 3.36Å; P89-A92 PolarHBondContact O-N 3.31Å; A92-G94 VanDerWaalsContact C-N 3.27Å; A92-G94 PolarHBondContact O-N 3.07Å; A92-G95 WeakPolarHBondContact O-CA 3.34Å; A92-G95 PolarHBondContact O-N 3.11Å; A92-F96 HydrophobicContact CB-CD2 4.36Å; A92-F96 HydrophobicContact CB-CE2 3.71Å; A92-F96 HydrophobicContact CB-CZ 4.24Å; A92-F96 WeakPolarHBondContact O-CD2 3.46Å; A92-F96 WeakPolarHBondContact O-CG 3.47Å; A92-F96 PolarHBondContact O-N 3.48Å; A92-I130 HydrophobicContact CB-CG2 4.29Å; A92-W131 HydrophobicContact CB-CD2 4.45Å; A92-W131 HydrophobicContact CB-CE3 4.07Å; A92-W131 HydrophobicContact CB-CH2 4.04Å; A92-W131 HydrophobicContact CB-CZ2 4.44Å; A92-W131 HydrophobicContact CB-CZ3 3.86Å; A92-V134 HydrophobicContact CB-CG2 4.29Å
93	S	97.8	Very high	96.3	Very high	1 Å²	1	8.4 Å²	8.4	1%	0.007	6%	0.059	C	C	.	.	H	α-helix	trans	-56.7	-39.3	173.9	-68.7	0	0	0	0	112.1	S51 D52 P89 Y91 F96 L97	S51-S93 WeakPolarHBondContact CB-OG 3.38Å; S51-S93 PolarHBondContact OG-OG 2.93Å; D52-S93 PolarHBondContact OD1-OG 2.74Å; P89-S93 WeakPolarHBondContact O-CB 3.44Å; P89-S93 PolarHBondContact O-N 2.78Å; P89-S93 PolarHBondContact O-OG 2.92Å; Y91-S93 VanDerWaalsContact C-N 3.28Å; Y91-S93 PolarHBondContact O-N 2.99Å; S93-F96 PolarHBondContact O-N 3.22Å; S93-L97 WeakPolarHBondContact O-CG 3.36Å; S93-L97 PolarHBondContact O-N 3.44Å
94	G	97.2	Very high	95.9	Very high	1 Å²	1	10.1 Å²	10.1	1%	0.01	6%	0.064	C	C	.	.	H	α-helix	trans	-62.3	-44.5	173.3	0	0	0	0	0	113.1	Y91 A92 L97 A98	Y91-G94 PolarHBondContact O-N 3.08Å; Y91-G94 VanDerWaalsContact O-N 3.1Å; A92-G94 VanDerWaalsContact C-N 3.27Å; A92-G94 PolarHBondContact O-N 3.07Å; G94-L97 PolarHBondContact O-N 3.06Å; G94-A98 PolarHBondContact O-N 3.02Å
95	G	98	Very high	95.6	Very high	12 Å²	12	9.4 Å²	9.4	12%	0.124	6%	0.058	C	C	.	.	H	α-helix	trans	-61.3	-42.9	173.9	0	0	0	0	0	113	Y91 A92 A98 A99	Y91-G95 PolarHBondContact O-N 2.84Å; A92-G95 WeakPolarHBondContact O-CA 3.34Å; A92-G95 PolarHBondContact O-N 3.11Å; G95-A98 PolarHBondContact O-N 2.99Å; G95-A99 PolarHBondContact O-N 3.28Å
96	F	97.9	Very high	95.1	Very high	0 Å²	0	11.5 Å²	11.5	0%	0	7%	0.066	C	C	.	.	H	α-helix	trans	-67.1	-36.5	177.4	-60.9	-47.5	0	0	0	112.5	H47 L48 A92 S93 A99 L100 C127 I130 W131	H47-F96 HydrophobicContact CB-CD1 3.93Å; H47-F96 HydrophobicContact CB-CD2 4.19Å; H47-F96 HydrophobicContact CB-CE1 3.69Å; H47-F96 HydrophobicContact CB-CE2 3.96Å; H47-F96 HydrophobicContact CB-CG 4.21Å; H47-F96 HydrophobicContact CB-CZ 3.73Å; L48-F96 HydrophobicContact CB-CB 3.94Å; L48-F96 HydrophobicContact CB-CD2 4.42Å; L48-F96 HydrophobicContact CB-CG 4.49Å; L48-F96 HydrophobicContact CD1-CB 4.28Å; A92-F96 HydrophobicContact CB-CD2 4.36Å; A92-F96 HydrophobicContact CB-CE2 3.71Å; A92-F96 HydrophobicContact CB-CZ 4.24Å; A92-F96 WeakPolarHBondContact O-CD2 3.46Å; A92-F96 WeakPolarHBondContact O-CG 3.47Å; A92-F96 PolarHBondContact O-N 3.48Å; S93-F96 PolarHBondContact O-N 3.22Å; F96-A99 PolarHBondContact O-N 3.43Å; F96-L100 WeakPolarHBondContact O-CB 3.42Å; F96-L100 PolarHBondContact O-N 3.35Å; F96-C127 HydrophobicContact CE1-CB 4.05Å; F96-I130 HydrophobicContact CD1-CD1 3.73Å; F96-I130 HydrophobicContact CD1-CG2 4.27Å; F96-I130 HydrophobicContact CE1-CB 3.95Å; F96-I130 HydrophobicContact CE1-CD1 3.9Å; F96-I130 HydrophobicContact CE1-CG2 3.8Å; F96-I130 HydrophobicContact CZ-CB 4.42Å; F96-I130 HydrophobicContact CZ-CG2 3.94Å; F96-W131 HydrophobicContact CE2-CZ2 4.06Å; F96-W131 AromaticContact CZ-CD1 3.81Å; F96-W131 HydrophobicContact CZ-CD2 4.3Å; F96-W131 AromaticContact CZ-CE2 3.78Å; F96-W131 HydrophobicContact CZ-CG 4.3Å; F96-W131 HydrophobicContact CZ-CZ2 4.29Å; F96-W131 AromaticContact CZ-NE1 3.5Å
97	L	96.1	Very high	94.5	Very high	2 Å²	2	12.9 Å²	12.9	1%	0.01	8%	0.08	C	C	.	.	H	α-helix	trans	-62.8	-41.1	172.5	-75.6	173.9	0	0	0	112	L48 S93 G94 L100 S101 A229 T232 L233	L48-L97 HydrophobicContact CD1-CG 4.37Å; L48-L97 HydrophobicContact CD2-CD2 3.7Å; L48-L97 HydrophobicContact CD2-CG 4.19Å; S93-L97 WeakPolarHBondContact O-CG 3.36Å; S93-L97 PolarHBondContact O-N 3.44Å; G94-L97 PolarHBondContact O-N 3.06Å; L97-L100 PolarHBondContact O-N 2.9Å; L97-S101 WeakPolarHBondContact O-CB 3.17Å; L97-S101 PolarHBondContact O-N 3.21Å; L97-S101 PolarHBondContact O-OG 3.17Å; L97-A229 HydrophobicContact CB-CB 4.36Å; L97-A229 HydrophobicContact CD2-CB 3.93Å; L97-T232 HydrophobicContact CD1-CG2 4.46Å; L97-L233 HydrophobicContact CD1-CD2 4.07Å; L97-L233 HydrophobicContact CD1-CG 4.18Å
98	A	96.8	Very high	93.8	Very high	5 Å²	5	14.9 Å²	14.9	4%	0.041	10%	0.098	C	C	.	.	H	α-helix	trans	-64.8	-46.6	175.4	0	0	0	0	0	111.6	G94 G95 L100 S101 A102 P194 I197 T198	G94-A98 PolarHBondContact O-N 3.02Å; G95-A98 PolarHBondContact O-N 2.99Å; A98-L100 PolarHBondContact O-N 3.37Å; A98-S101 PolarHBondContact O-N 3.08Å; A98-A102 WeakPolarHBondContact O-CB 3.11Å; A98-A102 PolarHBondContact O-N 2.85Å; A98-P194 HydrophobicContact CB-CB 3.93Å; A98-I197 HydrophobicContact CB-CB 4.22Å; A98-I197 HydrophobicContact CB-CG2 4.05Å; A98-T198 WeakPolarHBondContact CA-OG1 3.23Å
99	A	95.9	Very high	93.2	Very high	14 Å²	14	16.4 Å²	16.4	12%	0.116	11%	0.111	C	C	.	.	H	α-helix	trans	-62	-41.7	176.8	0	0	0	0	0	112.2	Y44 G95 F96 A102 G103 V126 I130	Y44-A99 HydrophobicContact CD1-CB 3.89Å; Y44-A99 HydrophobicContact CD2-CB 4.22Å; Y44-A99 HydrophobicContact CE1-CB 3.89Å; Y44-A99 HydrophobicContact CE2-CB 4.18Å; Y44-A99 WeakPolarHBondContact CE2-O 3.33Å; Y44-A99 HydrophobicContact CG-CB 4.09Å; G95-A99 PolarHBondContact O-N 3.28Å; F96-A99 PolarHBondContact O-N 3.43Å; A99-A102 PolarHBondContact O-N 3.1Å; A99-G103 PolarHBondContact O-N 3.49Å; A99-V126 HydrophobicContact CB-CG1 4.13Å; A99-I130 HydrophobicContact CB-CD1 4.23Å
100	L	92.8	Very high	92.5	Very high	0 Å²	0	21.4 Å²	21.4	0%	0	13%	0.133	C	C	.	.	H	α-helix	trans	-62.9	-42.3	174.8	-178.6	62.8	0	0	0	111.7	N41 F96 L97 A98 G103 R104 T276	N41-L100 HydrophobicContact CB-CD1 3.73Å; F96-L100 WeakPolarHBondContact O-CB 3.42Å; F96-L100 PolarHBondContact O-N 3.35Å; L97-L100 PolarHBondContact O-N 2.9Å; A98-L100 PolarHBondContact O-N 3.37Å; L100-G103 PolarHBondContact O-N 3.36Å; L100-R104 WeakPolarHBondContact O-CB 3.32Å; L100-R104 VanDerWaalsContact O-CG 3.28Å; L100-R104 WeakPolarHBondContact O-CG 3.28Å; L100-R104 PolarHBondContact O-N 3.38Å; L100-T276 HydrophobicContact CD2-CG2 4.15Å
101	S	92.8	Very high	91.3	Very high	4 Å²	4	24 Å²	24	3%	0.028	15%	0.15	C	C	.	.	H	α-helix	trans	-65.3	-42.6	177.2	-60.4	0	0	0	0	111.8	L97 A98 R104 Y105	L97-S101 WeakPolarHBondContact O-CB 3.17Å; L97-S101 PolarHBondContact O-N 3.21Å; L97-S101 PolarHBondContact O-OG 3.17Å; A98-S101 PolarHBondContact O-N 3.08Å; S101-R104 PolarHBondContact O-N 2.93Å; S101-Y105 WeakPolarHBondContact O-CB 3.36Å; S101-Y105 PolarHBondContact O-N 2.85Å
102	A	93.1	Very high	90	Very high	28 Å²	28	31.3 Å²	31.3	23%	0.231	18%	0.182	C	C	.	.	H	α-helix	trans	-62.7	-46.5	174.5	0	0	0	0	0	112	A98 A99 R104 Y105 L106 C201	A98-A102 WeakPolarHBondContact O-CB 3.11Å; A98-A102 PolarHBondContact O-N 2.85Å; A99-A102 PolarHBondContact O-N 3.1Å; A102-R104 VanDerWaalsContact C-N 3.25Å; A102-R104 PolarHBondContact O-N 3.43Å; A102-Y105 PolarHBondContact O-N 3.33Å; A102-L106 WeakPolarHBondContact O-CB 3.49Å; A102-L106 VanDerWaalsContact O-CG 3.31Å; A102-L106 WeakPolarHBondContact O-CG 3.24Å; A102-L106 PolarHBondContact O-N 3.47Å; A102-C201 WeakPolarHBondContact CA-SG 3.33Å
103	G	89.3	Confident	88.5	Confident	4 Å²	4	33.4 Å²	33.4	4%	0.041	20%	0.203	C	C	.	.	H	α-helix	trans	-61.3	-32.6	176.9	0	0	0	0	0	113.4	A99 L100 G107 Y114	A99-G103 PolarHBondContact O-N 3.49Å; L100-G103 PolarHBondContact O-N 3.36Å; G103-G107 PolarHBondContact O-N 2.92Å; G103-Y114 PolarHBondContact O-OH 3.3Å
104	R	86.9	Confident	87.1	Confident	44 Å²	44	34.7 Å²	34.7	17%	0.166	21%	0.208	C	C	.	.	H	α-helix	trans	-73.9	-45.4	173.7	-73.9	171.8	174.2	170	-3.8	112.1	L100 S101 A102 G107 A108 V225 T276	L100-R104 WeakPolarHBondContact O-CB 3.32Å; L100-R104 VanDerWaalsContact O-CG 3.28Å; L100-R104 WeakPolarHBondContact O-CG 3.28Å; L100-R104 PolarHBondContact O-N 3.38Å; S101-R104 PolarHBondContact O-N 2.93Å; A102-R104 VanDerWaalsContact C-N 3.25Å; A102-R104 PolarHBondContact O-N 3.43Å; R104-G107 PolarHBondContact O-N 3.23Å; R104-A108 PolarHBondContact O-N 3.02Å; R104-A108 VanDerWaalsContact O-N 3.08Å; R104-V225 PolarHBondContact NH1-O 2.85Å; R104-T276 PolarHBondContact NH2-O 3.13Å
105	Y	89.1	Confident	85.6	Confident	40 Å²	40	40.2 Å²	40.2	16%	0.157	23%	0.234	C	C	.	.	H	α-helix	trans	-59.5	-51.2	176.9	165.5	-120.9	0	0	0	111.8	S101 A102 G107 A108 A109 F110 F200 C201 G204 C205	S101-Y105 WeakPolarHBondContact O-CB 3.36Å; S101-Y105 PolarHBondContact O-N 2.85Å; A102-Y105 PolarHBondContact O-N 3.33Å; Y105-G107 VanDerWaalsContact C-N 3.27Å; Y105-G107 PolarHBondContact O-N 2.9Å; Y105-A108 PolarHBondContact O-N 3.24Å; Y105-A109 HydrophobicContact CD2-CB 4.04Å; Y105-A109 HydrophobicContact CE2-CB 3.54Å; Y105-A109 WeakPolarHBondContact O-CB 3.26Å; Y105-A109 PolarHBondContact O-N 2.97Å; Y105-F110 HydrophobicContact CE1-CE2 4.49Å; Y105-F200 AromaticContact CE1-CE1 3.92Å; Y105-F200 HydrophobicContact CE1-CE1 3.92Å; Y105-C201 HydrophobicContact CG-CB 4.48Å; Y105-G204 VanDerWaalsContact CD2-C 3.48Å; Y105-G204 VanDerWaalsContact CE2-CA 3.48Å; Y105-C205 WeakPolarHBondContact CA-SG 3.48Å
106	L	88.2	Confident	83.8	Confident	67 Å²	67	43.4 Å²	43.4	35%	0.351	26%	0.259	S	S	.	.	H	α-helix	trans	-59.5	-39.6	179.7	-68.8	172.8	0	0	0	111.9	A102 A108 F110 Y114	A102-L106 WeakPolarHBondContact O-CB 3.49Å; A102-L106 VanDerWaalsContact O-CG 3.31Å; A102-L106 WeakPolarHBondContact O-CG 3.24Å; A102-L106 PolarHBondContact O-N 3.47Å; L106-A108 VanDerWaalsContact C-N 3.32Å; L106-A108 PolarHBondContact O-N 3.46Å; L106-F110 HydrophobicContact CD2-CD2 3.94Å; L106-F110 HydrophobicContact CD2-CE2 4.2Å; L106-F110 CarbonylContact O-C 3.58Å; L106-F110 WeakPolarHBondContact O-CA 3.2Å; L106-F110 PolarHBondContact O-N 3.25Å; L106-Y114 HydrophobicContact CB-CD2 3.62Å; L106-Y114 HydrophobicContact CB-CE2 3.87Å; L106-Y114 HydrophobicContact CB-CG 4.1Å; L106-Y114 HydrophobicContact CD1-CD2 4.3Å; L106-Y114 HydrophobicContact CD1-CE2 4.16Å
107	G	83.9	Confident	82.3	Confident	31 Å²	31	48.7 Å²	48.7	32%	0.32	29%	0.287	S	S	.	.	H	α-helix	trans	-67.4	-29	176	0	0	0	0	0	114.4	G103 R104 Y105 Y114	G103-G107 PolarHBondContact O-N 2.92Å; R104-G107 PolarHBondContact O-N 3.23Å; Y105-G107 VanDerWaalsContact C-N 3.27Å; Y105-G107 PolarHBondContact O-N 2.9Å; G107-Y114 VanDerWaalsContact CA-CD1 3.46Å
108	A	82.4	Confident	81.1	Confident	49 Å²	49	52.1 Å²	52.1	41%	0.405	30%	0.299	S	S	.	.	H	α-helix	trans	-84.2	-42.2	178.3	0	0	0	0	0	112.5	R104 Y105 L106 A208	R104-A108 PolarHBondContact O-N 3.02Å; R104-A108 VanDerWaalsContact O-N 3.08Å; Y105-A108 PolarHBondContact O-N 3.24Å; L106-A108 VanDerWaalsContact C-N 3.32Å; L106-A108 PolarHBondContact O-N 3.46Å; A108-A208 HydrophobicContact CB-CB 4.36Å
109	A	85.4	Confident	80.5	Confident	34 Å²	34	59 Å²	59	28%	0.281	32%	0.324	S	S	.	.	H	α-helix	trans	-82.9	-31.4	-176.3	0	0	0	0	0	113.3	Y105 A208	Y105-A109 HydrophobicContact CD2-CB 4.04Å; Y105-A109 HydrophobicContact CE2-CB 3.54Å; Y105-A109 WeakPolarHBondContact O-CB 3.26Å; Y105-A109 PolarHBondContact O-N 2.97Å; A109-A208 HydrophobicContact CB-CB 4.21Å
110	F	83.8	Confident	80	Confident	107 Å²	107	59.9 Å²	59.9	47%	0.469	33%	0.329	S	S	.	.			trans	-130.7	64.5	-173.5	-52.6	-74.1	0	0	0	112	Y105 L106 F112 G113 Y114	Y105-F110 HydrophobicContact CE1-CE2 4.49Å; L106-F110 HydrophobicContact CD2-CD2 3.94Å; L106-F110 HydrophobicContact CD2-CE2 4.2Å; L106-F110 CarbonylContact O-C 3.58Å; L106-F110 WeakPolarHBondContact O-CA 3.2Å; L106-F110 PolarHBondContact O-N 3.25Å; F110-F112 VanDerWaalsContact C-N 3.33Å; F110-F112 PolarHBondContact O-N 3.47Å; F110-G113 PolarHBondContact O-N 3.42Å; F110-Y114 WeakPolarHBondContact O-CB 3.44Å; F110-Y114 PolarHBondContact O-N 2.91Å
111	P	73.9	Confident	79.9	Confident	58 Å²	58	66.9 Å²	66.9	38%	0.377	36%	0.355	S	S	.	.	H	α-helix	trans	-59.1	-38	-171.3	22.5	-33.5	0	0	0	113.9	Q115	P111-Q115 WeakPolarHBondContact O-CB 3.13Å; P111-Q115 WeakPolarHBondContact O-CG 3.48Å; P111-Q115 PolarHBondContact O-N 2.87Å
112	F	71.3	Confident	79.8	Confident	156 Å²	156	71.9 Å²	71.9	68%	0.684	37%	0.374	S	S	*	.	H	α-helix	trans	-82.3	-46	-179.7	-59.2	-69.5	0	0	0	112.7	F110 Q115	F110-F112 VanDerWaalsContact C-N 3.33Å; F110-F112 PolarHBondContact O-N 3.47Å; F112-Q115 PolarHBondContact O-N 3.08Å
113	G	65.6	Low	79.8	Confident	44 Å²	44	70.7 Å²	70.7	45%	0.454	36%	0.364	S	S	.	.	H	α-helix	trans	-66.7	-39.4	178.8	0	0	0	0	0	113.1	F110 A116	F110-G113 PolarHBondContact O-N 3.42Å; G113-A116 PolarHBondContact O-N 3.44Å
114	Y	69.4	Low	80.1	Confident	28 Å²	28	76.3 Å²	76.3	11%	0.11	38%	0.384	C	S	.	.	H	α-helix	trans	-68.1	-36.3	176.6	-173.2	-118.2	0	0	0	111.7	G103 L106 G107 F110 A116 I117 R118	G103-Y114 PolarHBondContact O-OH 3.3Å; L106-Y114 HydrophobicContact CB-CD2 3.62Å; L106-Y114 HydrophobicContact CB-CE2 3.87Å; L106-Y114 HydrophobicContact CB-CG 4.1Å; L106-Y114 HydrophobicContact CD1-CD2 4.3Å; L106-Y114 HydrophobicContact CD1-CE2 4.16Å; G107-Y114 VanDerWaalsContact CA-CD1 3.46Å; F110-Y114 WeakPolarHBondContact O-CB 3.44Å; F110-Y114 PolarHBondContact O-N 2.91Å; Y114-A116 VanDerWaalsContact C-N 3.26Å; Y114-A116 PolarHBondContact O-N 3.01Å; Y114-I117 CarbonylContact O-C 3.52Å; Y114-I117 PolarHBondContact O-N 2.87Å; Y114-R118 HydrophobicContact CD1-CB 4.5Å; Y114-R118 HydrophobicContact CD1-CG 4.36Å; Y114-R118 HydrophobicContact CE1-CB 4.42Å; Y114-R118 HydrophobicContact CE1-CG 3.89Å; Y114-R118 VanDerWaalsContact O-CB 3.22Å; Y114-R118 WeakPolarHBondContact O-CB 3.38Å; Y114-R118 PolarHBondContact O-N 2.93Å
115	Q	65.6	Low	80.6	Confident	117 Å²	117	76.2 Å²	76.2	55%	0.547	40%	0.397	S	S	.	.	H	α-helix	trans	-59.2	-34.7	177.2	-84.9	-171.8	17.4	0	0	113.3	P111 F112 I117	P111-Q115 WeakPolarHBondContact O-CB 3.13Å; P111-Q115 WeakPolarHBondContact O-CG 3.48Å; P111-Q115 PolarHBondContact O-N 2.87Å; F112-Q115 PolarHBondContact O-N 3.08Å; Q115-I117 VanDerWaalsContact C-N 3.34Å
116	A	61	Low	81	Confident	80 Å²	80	77.1 Å²	77.1	66%	0.661	41%	0.406	S	S	*	.	H	α-helix	trans	-68.2	-32.2	175.5	0	0	0	0	0	113.1	G113 Y114	G113-A116 PolarHBondContact O-N 3.44Å; Y114-A116 VanDerWaalsContact C-N 3.26Å; Y114-A116 PolarHBondContact O-N 3.01Å
117	I	66	Low	81.5	Confident	111 Å²	111	73.9 Å²	73.9	57%	0.569	39%	0.39	S	S	*	.	H	α-helix	trans	-98.5	-10.6	-174.2	-62.4	168	0	0	0	112.4	Y114 Q115 R119 Y122	Y114-I117 CarbonylContact O-C 3.52Å; Y114-I117 PolarHBondContact O-N 2.87Å; Q115-I117 VanDerWaalsContact C-N 3.34Å; I117-R119 PolarHBondContact O-N 3.44Å; I117-Y122 HydrophobicContact CG2-CE2 4.46Å; I117-Y122 WeakPolarHBondContact O-CD2 3.41Å
118	R	71.2	Confident	82.2	Confident	73 Å²	73	76.3 Å²	76.3	28%	0.275	40%	0.398	S	S	.	.			trans	-70	55.9	-174.1	-162	-178.4	179.6	-172.8	-0.3	114.3	P40 Y114	P40-R118 HydrophobicContact CG-CG 3.63Å; Y114-R118 HydrophobicContact CD1-CB 4.5Å; Y114-R118 HydrophobicContact CD1-CG 4.36Å; Y114-R118 HydrophobicContact CE1-CB 4.42Å; Y114-R118 HydrophobicContact CE1-CG 3.89Å; Y114-R118 VanDerWaalsContact O-CB 3.22Å; Y114-R118 WeakPolarHBondContact O-CB 3.38Å; Y114-R118 PolarHBondContact O-N 2.93Å
119	R	82.6	Confident	82.9	Confident	149 Å²	149	76.7 Å²	76.7	56%	0.562	40%	0.401	S	S	*	.			trans	-95.1	124.4	176.1	-57.1	-86.2	-172.9	157.2	-0.3	109.4	I117 R121 Y122	I117-R119 PolarHBondContact O-N 3.44Å; R119-R121 HydrophobicContact CB-CG 3.88Å; R119-R121 PolarHBondContact O-N 3.28Å; R119-R121 VanDerWaalsContact O-N 3.07Å; R119-Y122 HydrophobicContact CB-CD2 3.77Å; R119-Y122 HydrophobicContact CB-CE2 3.92Å; R119-Y122 HydrophobicContact CG-CD2 4.36Å; R119-Y122 HydrophobicContact CG-CE2 4.03Å; R119-Y122 PolarHBondContact O-N 3.33Å; R119-Y122 VanDerWaalsContact O-N 3.13Å
120	P	85.8	Confident	83.6	Confident	34 Å²	34	76.2 Å²	76.2	22%	0.221	39%	0.394	C	S	.	.	H	α-helix	trans	-55	-27.6	177.9	-28.2	35.5	0	0	0	114.9	L38 V43 Y122 S123 W124	L38-P120 HydrophobicContact CB-CG 4.43Å; L38-P120 HydrophobicContact CD2-CB 3.74Å; L38-P120 HydrophobicContact CD2-CG 4.25Å; L38-P120 HydrophobicContact CG-CB 3.98Å; L38-P120 HydrophobicContact CG-CG 4.14Å; L38-P120 WeakPolarHBondContact O-CG 3.31Å; V43-P120 HydrophobicContact CG2-CB 4.39Å; P120-Y122 VanDerWaalsContact C-N 3.25Å; P120-Y122 PolarHBondContact O-N 2.9Å; P120-S123 WeakPolarHBondContact O-CB 3.37Å; P120-S123 PolarHBondContact O-N 2.84Å; P120-W124 VanDerWaalsContact O-CD1 3.31Å; P120-W124 PolarHBondContact O-N 3.37Å; P120-W124 VanDerWaalsContact O-N 3.1Å
121	R	89.9	Confident	84.3	Confident	146 Å²	146	73.6 Å²	73.6	55%	0.551	38%	0.381	S	S	*	.	H	α-helix	trans	-55.4	-36.6	176.7	68.9	-172.2	171	89.4	-3	113.7	R119 S123 W124 G125	R119-R121 HydrophobicContact CB-CG 3.88Å; R119-R121 PolarHBondContact O-N 3.28Å; R119-R121 VanDerWaalsContact O-N 3.07Å; R121-S123 VanDerWaalsContact C-N 3.35Å; R121-W124 PolarHBondContact O-N 2.91Å; R121-G125 PolarHBondContact O-N 3.41Å; R121-G125 VanDerWaalsContact O-N 3.13Å
122	Y	91.3	Very high	85.4	Confident	109 Å²	109	74.5 Å²	74.5	43%	0.427	39%	0.385	S	S	.	.	H	α-helix	trans	-69.4	-36.9	177.9	-63.1	-54.6	0	0	0	111.3	I117 R119 P120 G125 V126	I117-Y122 HydrophobicContact CG2-CE2 4.46Å; I117-Y122 WeakPolarHBondContact O-CD2 3.41Å; R119-Y122 HydrophobicContact CB-CD2 3.77Å; R119-Y122 HydrophobicContact CB-CE2 3.92Å; R119-Y122 HydrophobicContact CG-CD2 4.36Å; R119-Y122 HydrophobicContact CG-CE2 4.03Å; R119-Y122 PolarHBondContact O-N 3.33Å; R119-Y122 VanDerWaalsContact O-N 3.13Å; P120-Y122 VanDerWaalsContact C-N 3.25Å; P120-Y122 PolarHBondContact O-N 2.9Å; Y122-G125 PolarHBondContact O-N 2.88Å; Y122-V126 WeakPolarHBondContact O-CG2 3.45Å; Y122-V126 PolarHBondContact O-N 3.21Å
123	S	93.6	Very high	86.7	Confident	3 Å²	3	70.7 Å²	70.7	2%	0.021	37%	0.371	C	S	.	.	H	α-helix	trans	-66.7	-37.1	176.1	-59.1	0	0	0	0	112.7	P40 Y44 P120 R121 V126 C127	P40-S123 WeakPolarHBondContact CA-OG 3.35Å; P40-S123 WeakPolarHBondContact CB-OG 3.06Å; Y44-S123 VanDerWaalsContact CZ-OG 3.31Å; Y44-S123 PolarHBondContact OH-OG 3.37Å; Y44-S123 VanDerWaalsContact OH-OG 3.1Å; P120-S123 WeakPolarHBondContact O-CB 3.37Å; P120-S123 PolarHBondContact O-N 2.84Å; R121-S123 VanDerWaalsContact C-N 3.35Å; S123-V126 PolarHBondContact O-N 2.98Å; S123-C127 WeakPolarHBondContact O-CB 3.43Å; S123-C127 PolarHBondContact O-N 3.48Å; S123-C127 PolarHBondContact O-SG 3.44Å
124	W	95.9	Very high	88.3	Confident	123 Å²	123	68.8 Å²	68.8	47%	0.466	35%	0.351	S	S	.	.	H	α-helix	trans	-60	-46.6	170.2	-78.4	104.8	0	0	0	111.6	V43 H47 P120 R121 V126 C127 V128	V43-W124 HydrophobicContact CG1-CD2 3.93Å; V43-W124 HydrophobicContact CG1-CE3 4.41Å; V43-W124 HydrophobicContact CG1-CG 4.08Å; H47-W124 AromaticContact NE2-CE3 3.57Å; H47-W124 AromaticContact NE2-CZ3 3.24Å; H47-W124 WeakPolarHBondContact NE2-CZ3 3.34Å; P120-W124 VanDerWaalsContact O-CD1 3.31Å; P120-W124 PolarHBondContact O-N 3.37Å; P120-W124 VanDerWaalsContact O-N 3.1Å; R121-W124 PolarHBondContact O-N 2.91Å; W124-V126 PolarHBondContact O-N 2.93Å; W124-C127 PolarHBondContact O-N 2.9Å; W124-V128 WeakPolarHBondContact O-CG2 3.39Å; W124-V128 PolarHBondContact O-N 2.88Å
125	G	97.3	Very high	89.6	Confident	41 Å²	41	71.2 Å²	71.2	42%	0.423	37%	0.365	S	S	.	.	H	α-helix	trans	-58.4	-45.5	175.6	0	0	0	0	0	113	R121 Y122 C127 V128 A129	R121-G125 PolarHBondContact O-N 3.41Å; R121-G125 VanDerWaalsContact O-N 3.13Å; Y122-G125 PolarHBondContact O-N 2.88Å; G125-C127 PolarHBondContact O-N 3.42Å; G125-V128 PolarHBondContact O-N 3.21Å; G125-A129 WeakPolarHBondContact O-CB 3.28Å; G125-A129 PolarHBondContact O-N 3.21Å
126	V	97.2	Very high	91.2	Very high	59 Å²	59	69.4 Å²	69.4	36%	0.358	36%	0.364	S	S	.	.	H	α-helix	trans	-61.5	-43.2	174.9	170.7	0	0	0	0	111.2	Y44 A99 Y122 S123 W124 V128 A129 I130	Y44-V126 HydrophobicContact CE1-CB 4.04Å; Y44-V126 HydrophobicContact CE1-CG1 3.89Å; A99-V126 HydrophobicContact CB-CG1 4.13Å; Y122-V126 WeakPolarHBondContact O-CG2 3.45Å; Y122-V126 PolarHBondContact O-N 3.21Å; S123-V126 PolarHBondContact O-N 2.98Å; W124-V126 PolarHBondContact O-N 2.93Å; V126-V128 PolarHBondContact O-N 3.44Å; V126-A129 PolarHBondContact O-N 3.4Å; V126-I130 HydrophobicContact CG1-CD1 3.88Å; V126-I130 HydrophobicContact CG1-CG1 4.49Å; V126-I130 VanDerWaalsContact O-CG1 3.32Å; V126-I130 WeakPolarHBondContact O-CG1 3.14Å; V126-I130 PolarHBondContact O-N 3.46Å
127	C	98.2	Very high	92.9	Very high	0 Å²	0	67.7 Å²	67.7	0%	0	34%	0.343	C	S	.	.	H	α-helix	trans	-63.2	-42.9	178.1	-74.7	0	0	0	0	112.8	Y44 H47 F96 S123 W124 G125 A129 I130 W131	Y44-C127 VanDerWaalsContact CD1-SG 3.56Å; H47-C127 VanDerWaalsContact CD2-SG 3.59Å; H47-C127 VanDerWaalsContact CG-SG 3.56Å; F96-C127 HydrophobicContact CE1-CB 4.05Å; S123-C127 WeakPolarHBondContact O-CB 3.43Å; S123-C127 PolarHBondContact O-N 3.48Å; S123-C127 PolarHBondContact O-SG 3.44Å; W124-C127 PolarHBondContact O-N 2.9Å; G125-C127 PolarHBondContact O-N 3.42Å; C127-A129 VanDerWaalsContact C-N 3.34Å; C127-I130 PolarHBondContact O-N 3.42Å; C127-W131 PolarHBondContact O-N 2.89Å; C127-W131 VanDerWaalsContact O-N 3.07Å
128	V	98.4	Very high	94.3	Very high	81 Å²	81	62.8 Å²	62.8	49%	0.491	32%	0.318	S	S	.	.	H	α-helix	trans	-62.3	-45	175	170.8	0	0	0	0	110	W124 G125 V126 I130 W131 V132	W124-V128 WeakPolarHBondContact O-CG2 3.39Å; W124-V128 PolarHBondContact O-N 2.88Å; G125-V128 PolarHBondContact O-N 3.21Å; V126-V128 PolarHBondContact O-N 3.44Å; V128-I130 VanDerWaalsContact C-N 3.34Å; V128-I130 PolarHBondContact O-N 3.26Å; V128-W131 PolarHBondContact O-N 3.37Å; V128-V132 HydrophobicContact CG1-CG2 4.14Å; V128-V132 WeakPolarHBondContact O-CB 3.31Å; V128-V132 VanDerWaalsContact O-CG2 3.3Å; V128-V132 WeakPolarHBondContact O-CG2 3.17Å; V128-V132 PolarHBondContact O-N 3.06Å
129	A	98.4	Very high	95.5	Very high	57 Å²	57	60.6 Å²	60.6	47%	0.471	32%	0.318	S	S	.	.	H	α-helix	trans	-60.5	-41.2	177.6	0	0	0	0	0	112.5	G125 V126 C127 L133	G125-A129 WeakPolarHBondContact O-CB 3.28Å; G125-A129 PolarHBondContact O-N 3.21Å; V126-A129 PolarHBondContact O-N 3.4Å; C127-A129 VanDerWaalsContact C-N 3.34Å; A129-L133 WeakPolarHBondContact O-CB 3.25Å; A129-L133 PolarHBondContact O-N 3.48Å
130	I	98.7	Very high	96.2	Very high	25 Å²	25	58.7 Å²	58.7	13%	0.128	32%	0.318	C	S	.	.	H	α-helix	trans	-61.1	-49.1	175	-69.7	163.6	0	0	0	110.6	A92 F96 A99 V126 C127 V128 L133 V134	A92-I130 HydrophobicContact CB-CG2 4.29Å; F96-I130 HydrophobicContact CD1-CD1 3.73Å; F96-I130 HydrophobicContact CD1-CG2 4.27Å; F96-I130 HydrophobicContact CE1-CB 3.95Å; F96-I130 HydrophobicContact CE1-CD1 3.9Å; F96-I130 HydrophobicContact CE1-CG2 3.8Å; F96-I130 HydrophobicContact CZ-CB 4.42Å; F96-I130 HydrophobicContact CZ-CG2 3.94Å; A99-I130 HydrophobicContact CB-CD1 4.23Å; V126-I130 HydrophobicContact CG1-CD1 3.88Å; V126-I130 HydrophobicContact CG1-CG1 4.49Å; V126-I130 VanDerWaalsContact O-CG1 3.32Å; V126-I130 WeakPolarHBondContact O-CG1 3.14Å; V126-I130 PolarHBondContact O-N 3.46Å; C127-I130 PolarHBondContact O-N 3.42Å; V128-I130 VanDerWaalsContact C-N 3.34Å; V128-I130 PolarHBondContact O-N 3.26Å; I130-L133 PolarHBondContact O-N 3.29Å; I130-V134 HydrophobicContact CG2-CG2 4.5Å; I130-V134 VanDerWaalsContact O-CG2 3.28Å; I130-V134 WeakPolarHBondContact O-CG2 3.34Å; I130-V134 PolarHBondContact O-N 2.75Å
131	W	98.5	Very high	96.6	Very high	52 Å²	52	57.8 Å²	57.8	20%	0.197	31%	0.312	C	S	.	.	H	α-helix	trans	-60.8	-48.2	178.5	-85.2	124.1	0	0	0	112.3	H47 P89 A92 F96 C127 V128 V134 L135	H47-W131 AromaticContact CE1-NE1 3.98Å; H47-W131 AromaticContact ND1-CD1 3.63Å; H47-W131 AromaticContact ND1-NE1 3.25Å; H47-W131 PolarHBondContact ND1-NE1 2.87Å; P89-W131 HydrophobicContact CB-CH2 4.34Å; P89-W131 HydrophobicContact CG-CH2 4.35Å; A92-W131 HydrophobicContact CB-CD2 4.45Å; A92-W131 HydrophobicContact CB-CE3 4.07Å; A92-W131 HydrophobicContact CB-CH2 4.04Å; A92-W131 HydrophobicContact CB-CZ2 4.44Å; A92-W131 HydrophobicContact CB-CZ3 3.86Å; F96-W131 HydrophobicContact CE2-CZ2 4.06Å; F96-W131 AromaticContact CZ-CD1 3.81Å; F96-W131 HydrophobicContact CZ-CD2 4.3Å; F96-W131 AromaticContact CZ-CE2 3.78Å; F96-W131 HydrophobicContact CZ-CG 4.3Å; F96-W131 HydrophobicContact CZ-CZ2 4.29Å; F96-W131 AromaticContact CZ-NE1 3.5Å; C127-W131 PolarHBondContact O-N 2.89Å; C127-W131 VanDerWaalsContact O-N 3.07Å; V128-W131 PolarHBondContact O-N 3.37Å; W131-V134 PolarHBondContact O-N 3.43Å; W131-L135 HydrophobicContact CE3-CD1 4.2Å; W131-L135 HydrophobicContact CE3-CG 4.34Å; W131-L135 VanDerWaalsContact O-CB 3.27Å; W131-L135 WeakPolarHBondContact O-CB 2.98Å; W131-L135 VanDerWaalsContact O-CG 3.28Å; W131-L135 WeakPolarHBondContact O-CG 3.33Å; W131-L135 PolarHBondContact O-N 2.99Å
132	V	98.6	Very high	96.8	Very high	77 Å²	77	51.2 Å²	51.2	47%	0.467	29%	0.288	S	S	.	.	H	α-helix	trans	-60	-47.8	178.2	169.8	0	0	0	0	110.3	V128 V134 L135 C136	V128-V132 HydrophobicContact CG1-CG2 4.14Å; V128-V132 WeakPolarHBondContact O-CB 3.31Å; V128-V132 VanDerWaalsContact O-CG2 3.3Å; V128-V132 WeakPolarHBondContact O-CG2 3.17Å; V128-V132 PolarHBondContact O-N 3.06Å; V132-V134 PolarHBondContact O-N 2.88Å; V132-L135 PolarHBondContact O-N 3.34Å; V132-C136 WeakPolarHBondContact O-CB 3.45Å; V132-C136 PolarHBondContact O-N 3.33Å; V132-C136 PolarHBondContact O-SG 2.99Å
133	L	98.2	Very high	96.9	Very high	76 Å²	76	47.4 Å²	47.4	40%	0.398	28%	0.282	S	S	.	.	H	α-helix	trans	-56.9	-50	178.6	178.6	64.6	0	0	0	111.6	A129 I130 H137 L189 L190	A129-L133 WeakPolarHBondContact O-CB 3.25Å; A129-L133 PolarHBondContact O-N 3.48Å; I130-L133 PolarHBondContact O-N 3.29Å; L133-H137 WeakPolarHBondContact O-CB 3.33Å; L133-H137 PolarHBondContact O-N 3.36Å; L133-L189 HydrophobicContact CD1-CD2 4.14Å; L133-L190 HydrophobicContact CD2-CD2 4.25Å; L133-L190 HydrophobicContact CG-CD2 4.17Å
134	V	98.3	Very high	96.9	Very high	3 Å²	3	50.3 Å²	50.3	2%	0.018	30%	0.296	C	S	.	.	H	α-helix	trans	-65.6	-50	-178.4	174.7	0	0	0	0	111	A88 A92 I130 W131 V132 M138 L190	A88-V134 HydrophobicContact CB-CG1 3.76Å; A88-V134 WeakPolarHBondContact O-CG1 3.43Å; A92-V134 HydrophobicContact CB-CG2 4.29Å; I130-V134 HydrophobicContact CG2-CG2 4.5Å; I130-V134 VanDerWaalsContact O-CG2 3.28Å; I130-V134 WeakPolarHBondContact O-CG2 3.34Å; I130-V134 PolarHBondContact O-N 2.75Å; W131-V134 PolarHBondContact O-N 3.43Å; V132-V134 PolarHBondContact O-N 2.88Å; V134-M138 HydrophobicContact CG1-CG 4.33Å; V134-M138 WeakPolarHBondContact O-CB 3.35Å; V134-M138 WeakPolarHBondContact O-CG 3.16Å; V134-M138 PolarHBondContact O-N 2.99Å; V134-L190 HydrophobicContact CG1-CD1 4.39Å; V134-L190 HydrophobicContact CG2-CD1 4.38Å; V134-L190 HydrophobicContact CG2-CD2 3.93Å
135	L	98	Very high	96.7	Very high	79 Å²	79	47.7 Å²	47.7	41%	0.414	29%	0.289	S	S	.	.	H	α-helix	trans	-67.8	-42.5	-176.2	-70.8	169.6	0	0	0	112	A88 W131 V132 G139	A88-L135 HydrophobicContact CB-CD2 3.77Å; W131-L135 HydrophobicContact CE3-CD1 4.2Å; W131-L135 HydrophobicContact CE3-CG 4.34Å; W131-L135 VanDerWaalsContact O-CB 3.27Å; W131-L135 WeakPolarHBondContact O-CB 2.98Å; W131-L135 VanDerWaalsContact O-CG 3.28Å; W131-L135 WeakPolarHBondContact O-CG 3.33Å; W131-L135 PolarHBondContact O-N 2.99Å; V132-L135 PolarHBondContact O-N 3.34Å; L135-G139 WeakPolarHBondContact O-CA 3.33Å; L135-G139 PolarHBondContact O-N 2.91Å
136	C	97.8	Very high	96.5	Very high	79 Å²	79	45.8 Å²	45.8	53%	0.534	27%	0.269	S	S	.	.	H	α-helix	trans	-67.2	-46.7	177.5	-69.6	0	0	0	0	111.1	V132 L140	V132-C136 WeakPolarHBondContact O-CB 3.45Å; V132-C136 PolarHBondContact O-N 3.33Å; V132-C136 PolarHBondContact O-SG 2.99Å; C136-L140 WeakPolarHBondContact O-CB 3.49Å; C136-L140 PolarHBondContact O-N 3.36Å
137	H	97.1	Very high	96.2	Very high	44 Å²	44	43.8 Å²	43.8	20%	0.204	26%	0.258	C	S	.	.	H	α-helix	trans	-64.5	-47.5	-179.1	-170.5	56.3	0	0	0	111.6	L133 V141 S185 F186	L133-H137 WeakPolarHBondContact O-CB 3.33Å; L133-H137 PolarHBondContact O-N 3.36Å; H137-V141 WeakPolarHBondContact O-CB 3.1Å; H137-V141 VanDerWaalsContact O-CG2 3.29Å; H137-V141 WeakPolarHBondContact O-CG2 3.45Å; H137-V141 PolarHBondContact O-N 3.25Å; H137-V141 VanDerWaalsContact O-N 3.14Å; H137-S185 PolarHBondContact NE2-OG 2.84Å; H137-S185 VanDerWaalsContact NE2-OG 3.08Å; H137-F186 AromaticContact CD2-CD1 3.39Å; H137-F186 WeakPolarHBondContact CD2-CD1 3.34Å; H137-F186 AromaticContact CD2-CE1 3.65Å; H137-F186 AromaticContact NE2-CD1 3.47Å; H137-F186 WeakPolarHBondContact NE2-CD1 3.48Å; H137-F186 AromaticContact NE2-CE1 3.75Å
138	M	96.3	Very high	95.8	Very high	9 Å²	9	44.7 Å²	44.7	4%	0.044	27%	0.267	C	S	.	.	H	α-helix	trans	-63	-48.7	175.2	-74.6	-93.2	-167.9	0	0	112.5	L84 F87 Y91 V134 L140 V141 L142 F186 L190	L84-M138 HydrophobicContact CD2-CB 4Å; F87-M138 HydrophobicContact CB-CE 3.76Å; F87-M138 HydrophobicContact CB-SD 4.19Å; Y91-M138 HydrophobicContact CD2-CE 3.03Å; Y91-M138 HydrophobicContact CE2-CE 3.36Å; Y91-M138 HydrophobicContact CG-CE 3.99Å; V134-M138 HydrophobicContact CG1-CG 4.33Å; V134-M138 WeakPolarHBondContact O-CB 3.35Å; V134-M138 WeakPolarHBondContact O-CG 3.16Å; V134-M138 PolarHBondContact O-N 2.99Å; M138-L140 PolarHBondContact O-N 3.39Å; M138-V141 PolarHBondContact O-N 3.28Å; M138-L142 VanDerWaalsContact O-CB 3.23Å; M138-L142 WeakPolarHBondContact O-CB 2.99Å; M138-L142 PolarHBondContact O-N 2.9Å; M138-F186 HydrophobicContact CE-CD2 4.45Å; M138-F186 HydrophobicContact CE-CG 4.42Å; M138-F186 HydrophobicContact CG-CE1 4.32Å; M138-F186 HydrophobicContact SD-CD1 4.41Å; M138-F186 HydrophobicContact SD-CD2 4.21Å; M138-F186 HydrophobicContact SD-CE1 4.15Å; M138-F186 HydrophobicContact SD-CE2 3.94Å; M138-F186 HydrophobicContact SD-CG 4.44Å; M138-F186 HydrophobicContact SD-CZ 3.89Å; M138-L190 HydrophobicContact CE-CD1 4.26Å
139	G	96.1	Very high	95.4	Very high	27 Å²	27	41.1 Å²	41.1	28%	0.278	25%	0.247	S	C	.	.	H	α-helix	trans	-65.4	-38.8	-176.4	0	0	0	0	0	112.2	L135 G143	L135-G139 WeakPolarHBondContact O-CA 3.33Å; L135-G139 PolarHBondContact O-N 2.91Å; G139-G143 PolarHBondContact O-N 3.02Å
140	L	96.1	Very high	95.1	Very high	109 Å²	109	48.4 Å²	48.4	57%	0.571	26%	0.262	S	S	*	.	H	α-helix	trans	-65.5	-50.3	176	-175.7	66	0	0	0	111.1	C136 M138 L142 G143 L144	C136-L140 WeakPolarHBondContact O-CB 3.49Å; C136-L140 PolarHBondContact O-N 3.36Å; M138-L140 PolarHBondContact O-N 3.39Å; L140-L142 PolarHBondContact O-N 2.69Å; L140-G143 PolarHBondContact O-N 3.4Å; L140-L144 HydrophobicContact CD1-CD1 3.59Å; L140-L144 HydrophobicContact CD1-CG 4.05Å; L140-L144 HydrophobicContact CG-CD1 3.87Å; L140-L144 HydrophobicContact CG-CG 4.5Å; L140-L144 WeakPolarHBondContact O-CB 3.42Å; L140-L144 VanDerWaalsContact O-CG 3.31Å; L140-L144 WeakPolarHBondContact O-CG 3.36Å; L140-L144 PolarHBondContact O-N 3.15Å
141	V	95.1	Very high	94.6	Very high	14 Å²	14	52.9 Å²	52.9	9%	0.085	29%	0.286	C	S	.	.	H	α-helix	trans	-62.3	-44	179	169.2	0	0	0	0	111	H137 M138 E145 W174 A182 F186	H137-V141 WeakPolarHBondContact O-CB 3.1Å; H137-V141 VanDerWaalsContact O-CG2 3.29Å; H137-V141 WeakPolarHBondContact O-CG2 3.45Å; H137-V141 PolarHBondContact O-N 3.25Å; H137-V141 VanDerWaalsContact O-N 3.14Å; M138-V141 PolarHBondContact O-N 3.28Å; V141-E145 WeakPolarHBondContact O-CB 3.32Å; V141-E145 PolarHBondContact O-N 3.17Å; V141-W174 HydrophobicContact CG1-CH2 4.01Å; V141-A182 HydrophobicContact CG1-CB 3.52Å; V141-F186 HydrophobicContact CB-CE1 3.86Å; V141-F186 HydrophobicContact CB-CZ 3.66Å; V141-F186 HydrophobicContact CG1-CE1 4.01Å; V141-F186 HydrophobicContact CG1-CE2 4.28Å; V141-F186 HydrophobicContact CG1-CZ 3.46Å; V141-F186 VanDerWaalsContact CG1-CZ 3.46Å; V141-F186 HydrophobicContact CG2-CE1 3.88Å; V141-F186 HydrophobicContact CG2-CZ 4.18Å
142	L	93.5	Very high	93.8	Very high	9 Å²	9	53 Å²	53	5%	0.047	29%	0.292	C	S	.	.	H	α-helix	trans	-63.7	-48	176.4	-177.2	70.3	0	0	0	111.3	V83 L84 M138 L140 L144 A146 L158 L171	V83-L142 HydrophobicContact CG1-CD1 4.47Å; V83-L142 HydrophobicContact CG1-CD2 4.27Å; L84-L142 HydrophobicContact CG-CD2 4.41Å; M138-L142 VanDerWaalsContact O-CB 3.23Å; M138-L142 WeakPolarHBondContact O-CB 2.99Å; M138-L142 PolarHBondContact O-N 2.9Å; L140-L142 PolarHBondContact O-N 2.69Å; L142-L144 VanDerWaalsContact C-N 3.32Å; L142-L144 PolarHBondContact O-N 3.04Å; L142-A146 HydrophobicContact CD1-CB 3.32Å; L142-A146 HydrophobicContact CG-CB 4.14Å; L142-A146 WeakPolarHBondContact O-CB 3.3Å; L142-A146 PolarHBondContact O-N 2.76Å; L142-L158 HydrophobicContact CD2-CD2 4.33Å; L142-L158 HydrophobicContact CG-CD2 4.29Å; L142-L158 HydrophobicContact CG-CG 4.32Å; L142-L171 HydrophobicContact CD1-CD1 3.72Å
143	G	93.5	Very high	92.8	Very high	29 Å²	29	56.9 Å²	56.9	30%	0.299	31%	0.31	S	S	.	.	H	α-helix	trans	-67	-29.5	-177.2	0	0	0	0	0	114	G139 L140 G149 W150	G139-G143 PolarHBondContact O-N 3.02Å; L140-G143 PolarHBondContact O-N 3.4Å; G143-G149 CarbonylContact O-C 3.55Å; G143-G149 VanDerWaalsContact O-CA 3.23Å; G143-G149 WeakPolarHBondContact O-CA 3.45Å; G143-W150 PolarHBondContact O-N 2.8Å
144	L	93.4	Very high	91.8	Very high	63 Å²	63	56.9 Å²	56.9	33%	0.33	31%	0.314	S	S	.	.	H	α-helix	trans	-90.3	-49.9	179.7	-67.3	179.4	0	0	0	112.9	L140 L142 W150 L151	L140-L144 HydrophobicContact CD1-CD1 3.59Å; L140-L144 HydrophobicContact CD1-CG 4.05Å; L140-L144 HydrophobicContact CG-CD1 3.87Å; L140-L144 HydrophobicContact CG-CG 4.5Å; L140-L144 WeakPolarHBondContact O-CB 3.42Å; L140-L144 VanDerWaalsContact O-CG 3.31Å; L140-L144 WeakPolarHBondContact O-CG 3.36Å; L140-L144 PolarHBondContact O-N 3.15Å; L142-L144 VanDerWaalsContact C-N 3.32Å; L142-L144 PolarHBondContact O-N 3.04Å; L144-W150 HydrophobicContact CD2-CB 4.03Å; L144-W150 HydrophobicContact CD2-CG 4.47Å; L144-W150 PolarHBondContact O-N 3.33Å; L144-L151 HydrophobicContact CB-CD1 4.33Å; L144-L151 VanDerWaalsContact O-CB 3.27Å; L144-L151 WeakPolarHBondContact O-CB 3.32Å; L144-L151 WeakPolarHBondContact O-CG 3.47Å; L144-L151 PolarHBondContact O-N 3.24Å
145	E	92.3	Very high	90.8	Very high	69 Å²	69	64.2 Å²	64.2	32%	0.322	36%	0.359	S	S	.	.	H	α-helix	trans	-108.4	-18.1	-163	-59.9	-176.6	-177.7	0	0	114.5	V141 L151 W174	V141-E145 WeakPolarHBondContact O-CB 3.32Å; V141-E145 PolarHBondContact O-N 3.17Å; E145-L151 HydrophobicContact CG-CD1 4.3Å; E145-W174 VanDerWaalsContact C-CZ2 3.49Å; E145-W174 HydrophobicContact CB-CH2 4.5Å; E145-W174 HydrophobicContact CB-CZ2 3.78Å; E145-W174 WeakPolarHBondContact O-CZ2 3.44Å; E145-W174 PolarHBondContact O-NE1 3.19Å; E145-W174 VanDerWaalsContact O-NE1 3.1Å
146	A	92.2	Very high	90.1	Very high	0 Å²	0	62.7 Å²	62.7	0%	0	36%	0.355	C	S	.	.	S	Bend	trans	-73.7	163.9	-178.6	0	0	0	0	0	112.1	L142 G148 G149 T152 W174	L142-A146 HydrophobicContact CD1-CB 3.32Å; L142-A146 HydrophobicContact CG-CB 4.14Å; L142-A146 WeakPolarHBondContact O-CB 3.3Å; L142-A146 PolarHBondContact O-N 2.76Å; A146-G148 PolarHBondContact O-N 3.18Å; A146-G149 WeakPolarHBondContact O-CA 3.46Å; A146-G149 PolarHBondContact O-N 3.11Å; A146-T152 WeakPolarHBondContact O-CG2 3.38Å; A146-W174 HydrophobicContact CB-CD2 4.43Å; A146-W174 HydrophobicContact CB-CE3 4.48Å; A146-W174 HydrophobicContact CB-CH2 4.05Å; A146-W174 HydrophobicContact CB-CZ2 4.02Å; A146-W174 HydrophobicContact CB-CZ3 4.28Å
147	P	91	Very high	89.7	Confident	17 Å²	17	60.7 Å²	60.7	11%	0.11	34%	0.342	C	S	.	.	T	Hydrogen-bonded Turn	trans	-55.3	130.4	175.6	-24.4	34.9	0	0	0	111.3	G149 L158 G159 I160 S161 W174	P147-G149 PolarHBondContact O-N 3.06Å; P147-L158 CarbonylContact O-C 3.57Å; P147-L158 WeakPolarHBondContact O-CA 3.37Å; P147-G159 PolarHBondContact O-N 3.1Å; P147-I160 WeakPolarHBondContact CB-O 3.39Å; P147-S161 WeakPolarHBondContact CG-OG 3.35Å; P147-W174 HydrophobicContact CG-CB 4.35Å; P147-W174 HydrophobicContact CG-CG 4.23Å
148	G	89.6	Confident	89.5	Confident	20 Å²	20	61.2 Å²	61.2	21%	0.206	35%	0.345	C	S	.	.	T	Hydrogen-bonded Turn	trans	73.7	9.1	-173.2	0	0	0	0	0	114.3	A146 T152 S156	A146-G148 PolarHBondContact O-N 3.18Å; G148-T152 PolarHBondContact N-OG1 3.11Å; G148-T152 VanDerWaalsContact N-OG1 3.11Å; G148-S156 WeakPolarHBondContact CA-O 3.47Å; G148-S156 VanDerWaalsContact CA-OG 3.31Å; G148-S156 WeakPolarHBondContact CA-OG 3.39Å; G148-S156 PolarHBondContact N-OG 2.91Å
149	G	91.4	Very high	89.2	Confident	6 Å²	6	60.8 Å²	60.8	6%	0.062	34%	0.343	C	S	.	.	S	Bend	trans	-82.6	170.1	169.6	0	0	0	0	0	112.2	G143 A146 P147 L151 T152	G143-G149 CarbonylContact O-C 3.55Å; G143-G149 VanDerWaalsContact O-CA 3.23Å; G143-G149 WeakPolarHBondContact O-CA 3.45Å; A146-G149 WeakPolarHBondContact O-CA 3.46Å; A146-G149 PolarHBondContact O-N 3.11Å; P147-G149 PolarHBondContact O-N 3.06Å; G149-L151 VanDerWaalsContact C-N 3.31Å; G149-L151 PolarHBondContact O-N 2.93Å; G149-T152 PolarHBondContact N-OG1 3.43Å; G149-T152 PolarHBondContact O-N 3.4Å; G149-T152 PolarHBondContact O-OG1 3.03Å
150	W	90.4	Very high	89.2	Confident	210 Å²	210	59.7 Å²	59.7	80%	0.795	33%	0.331	S	S	*	.	G	3₁₀ helix	trans	-54.2	-41.6	-170.3	-173.3	-97.7	0	0	0	114	G143 L144	G143-W150 PolarHBondContact O-N 2.8Å; L144-W150 HydrophobicContact CD2-CB 4.03Å; L144-W150 HydrophobicContact CD2-CG 4.47Å; L144-W150 PolarHBondContact O-N 3.33Å
151	L	88.9	Confident	88.9	Confident	119 Å²	119	55.6 Å²	55.6	62%	0.623	31%	0.312	S	S	*	.	G	3₁₀ helix	trans	-79.5	-18.8	-176.8	-62.5	173.4	0	0	0	113.5	L144 E145 G149	L144-L151 HydrophobicContact CB-CD1 4.33Å; L144-L151 VanDerWaalsContact O-CB 3.27Å; L144-L151 WeakPolarHBondContact O-CB 3.32Å; L144-L151 WeakPolarHBondContact O-CG 3.47Å; L144-L151 PolarHBondContact O-N 3.24Å; E145-L151 HydrophobicContact CG-CD1 4.3Å; G149-L151 VanDerWaalsContact C-N 3.31Å; G149-L151 PolarHBondContact O-N 2.93Å
152	T	82.8	Confident	88.6	Confident	54 Å²	54	60.2 Å²	60.2	33%	0.331	34%	0.335	S	S	.	.	G	3₁₀ helix	trans	-79.1	-19.7	-179.1	58.3	0	0	0	0	113.2	A146 G148 G149 T154	A146-T152 WeakPolarHBondContact O-CG2 3.38Å; G148-T152 PolarHBondContact N-OG1 3.11Å; G148-T152 VanDerWaalsContact N-OG1 3.11Å; G149-T152 PolarHBondContact N-OG1 3.43Å; G149-T152 PolarHBondContact O-N 3.4Å; G149-T152 PolarHBondContact O-OG1 3.03Å; T152-T154 PolarHBondContact O-N 3.45Å
153	N	77.4	Confident	88.1	Confident	158 Å²	158	62.3 Å²	62.3	85%	0.845	35%	0.349	S	S	*	.			trans	50.5	37.3	177.1	-158.5	20.1	0	0	0	114.2
154	T	77.1	Confident	87.3	Confident	76 Å²	76	68.2 Å²	68.2	47%	0.466	38%	0.379	S	S	.	.			trans	-113.5	152.4	177.7	54.6	0	0	0	0	111.4	T152 S156	T152-T154 PolarHBondContact O-N 3.45Å; T154-S156 PolarHBondContact O-N 3.31Å; T154-S156 PolarHBondContact OG1-OG 3.14Å
155	T	76.9	Confident	86.4	Confident	158 Å²	158	72.1 Å²	72.1	97%	0.969	40%	0.4	S	S	*	.			trans	-83.2	17.6	174.7	56.5	0	0	0	0	113.4
156	S	82.1	Confident	86	Confident	47 Å²	47	71.2 Å²	71.2	33%	0.329	41%	0.41	S	S	.	.	S	Bend	trans	-75.9	149.7	178.6	49.4	0	0	0	0	111.5	G148 T154	G148-S156 WeakPolarHBondContact CA-O 3.47Å; G148-S156 VanDerWaalsContact CA-OG 3.31Å; G148-S156 WeakPolarHBondContact CA-OG 3.39Å; G148-S156 PolarHBondContact N-OG 2.91Å; T154-S156 PolarHBondContact O-N 3.31Å; T154-S156 PolarHBondContact OG1-OG 3.14Å
157	S	89.8	Confident	85.9	Confident	37 Å²	37	74 Å²	74	26%	0.259	43%	0.429	S	S	.	.	P	Polyproline II helix	trans	-62.1	139.8	171.7	-59.9	0	0	0	0	111.4	L76 G159 I160	L76-S157 WeakPolarHBondContact CB-OG 3.4Å; S157-G159 PolarHBondContact O-N 3.1Å; S157-I160 WeakPolarHBondContact O-CB 3.47Å; S157-I160 PolarHBondContact O-N 2.7Å
158	L	92.8	Very high	86	Confident	54 Å²	54	75 Å²	75	28%	0.283	44%	0.435	S	S	.	.	T	Hydrogen-bonded Turn	trans	-57.2	124.5	-175.6	-174.2	65.8	0	0	0	112.5	L142 P147 I160	L142-L158 HydrophobicContact CD2-CD2 4.33Å; L142-L158 HydrophobicContact CG-CD2 4.29Å; L142-L158 HydrophobicContact CG-CG 4.32Å; P147-L158 CarbonylContact O-C 3.57Å; P147-L158 WeakPolarHBondContact O-CA 3.37Å; L158-I160 VanDerWaalsContact C-N 3.34Å
159	G	91.8	Very high	86.2	Confident	0 Å²	0	75 Å²	75	0%	0	43%	0.431	C	S	.	.	T	Hydrogen-bonded Turn	trans	84.1	-3.1	-179.5	0	0	0	0	0	115.1	C79 P147 S157 L171	C79-G159 VanDerWaalsContact SG-C 3.55Å; C79-G159 PolarHBondContact SG-O 3.18Å; C79-G159 VanDerWaalsContact SG-O 3.37Å; P147-G159 PolarHBondContact O-N 3.1Å; S157-G159 PolarHBondContact O-N 3.1Å; G159-L171 PolarHBondContact O-N 3.43Å
160	I	94.2	Very high	86.3	Confident	5 Å²	5	74.9 Å²	74.9	3%	0.026	43%	0.429	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-94.2	129.1	179.8	-65.9	-68.8	0	0	0	110.9	W72 L76 C79 P147 S157 L158 I162 P168 C170	W72-I160 HydrophobicContact CB-CD1 4.38Å; W72-I160 HydrophobicContact CG-CD1 4.01Å; L76-I160 HydrophobicContact CB-CG1 4.2Å; L76-I160 HydrophobicContact CD2-CD1 4.18Å; L76-I160 HydrophobicContact CD2-CG1 4.26Å; L76-I160 HydrophobicContact CD2-CG2 4.2Å; C79-I160 HydrophobicContact CB-CD1 3.51Å; C79-I160 HydrophobicContact CB-CG1 3.87Å; P147-I160 WeakPolarHBondContact CB-O 3.39Å; S157-I160 WeakPolarHBondContact O-CB 3.47Å; S157-I160 PolarHBondContact O-N 2.7Å; L158-I160 VanDerWaalsContact C-N 3.34Å; I160-I162 HydrophobicContact CG2-CG1 4.17Å; I160-P168 HydrophobicContact CG2-CB 4.21Å; I160-C170 HydrophobicContact CD1-CB 4.2Å
161	S	91.3	Very high	86.3	Confident	22 Å²	22	65.6 Å²	65.6	15%	0.154	40%	0.396	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-113.3	139.3	164.9	-62.7	0	0	0	0	109.8	P147 P163 V169 A173	P147-S161 WeakPolarHBondContact CG-OG 3.35Å; S161-P163 WeakPolarHBondContact O-CD 3.42Å; S161-V169 PolarHBondContact N-O 3.38Å; S161-V169 PolarHBondContact O-N 2.88Å; S161-A173 VanDerWaalsContact CB-O 3.3Å; S161-A173 WeakPolarHBondContact CB-O 3.3Å; S161-A173 PolarHBondContact OG-O 2.69Å
162	I	88.6	Confident	86.3	Confident	111 Å²	111	62.1 Å²	62.1	57%	0.569	38%	0.376	S	S	*	.			trans	-112.6	96.5	173.1	-54.8	175.2	0	0	0	107.5	I160	I160-I162 HydrophobicContact CG2-CG1 4.17Å
163	P	83.6	Confident	86.5	Confident	54 Å²	54	61.6 Å²	61.6	35%	0.351	38%	0.377	S	S	.	.			trans	-66.5	170.5	175.9	30.6	-34.4	0	0	0	111.2	S161 N165 G166 S167 V169	S161-P163 WeakPolarHBondContact O-CD 3.42Å; P163-N165 PolarHBondContact O-N 3.14Å; P163-G166 PolarHBondContact O-N 3.05Å; P163-S167 WeakPolarHBondContact CD-O 3.43Å; P163-V169 HydrophobicContact CG-CG2 4.22Å
164	V	76.1	Confident	87.2	Confident	153 Å²	153	54.7 Å²	54.7	93%	0.927	34%	0.339	S	S	*	.	T	Hydrogen-bonded Turn	trans	-52.9	-26.7	-177.2	-173	0	0	0	0	113.2	G166	V164-G166 PolarHBondContact O-N 3.27Å
165	N	74.3	Confident	87.8	Confident	144 Å²	144	54.7 Å²	54.7	77%	0.77	34%	0.336	S	S	*	.	T	Hydrogen-bonded Turn	trans	-74.7	0.8	177.1	-60.5	0.5	0	0	0	114.1	P163 S167	P163-N165 PolarHBondContact O-N 3.14Å; N165-S167 PolarHBondContact O-N 3.2Å; N165-S167 VanDerWaalsContact O-N 3.13Å
166	G	83.4	Confident	88.5	Confident	51 Å²	51	50 Å²	50	53%	0.526	31%	0.308	S	S	.	.			trans	76.1	-7.6	172.8	0	0	0	0	0	116.5	P163 V164	P163-G166 PolarHBondContact O-N 3.05Å; V164-G166 PolarHBondContact O-N 3.27Å
167	S	89.6	Confident	88.9	Confident	59 Å²	59	53.5 Å²	53.5	41%	0.413	32%	0.324	S	S	.	.			trans	-87.8	125	-177.9	-62.7	0	0	0	0	111.8	P163 N165	P163-S167 WeakPolarHBondContact CD-O 3.43Å; N165-S167 PolarHBondContact O-N 3.2Å; N165-S167 VanDerWaalsContact O-N 3.13Å
168	P	93.3	Very high	89	Confident	37 Å²	37	53.8 Å²	53.8	24%	0.24	33%	0.326	C	S	.	.			trans	-65	138.3	-179.1	27.9	-34.7	0	0	0	111.2	A71 W72 L76 I160	A71-P168 WeakPolarHBondContact CA-O 3.48Å; W72-P168 HydrophobicContact CB-CB 4.44Å; W72-P168 WeakPolarHBondContact CB-O 3.35Å; W72-P168 PolarHBondContact N-O 3.49Å; L76-P168 HydrophobicContact CD2-CB 3.8Å; L76-P168 HydrophobicContact CD2-CG 4.22Å; I160-P168 HydrophobicContact CG2-CB 4.21Å
169	V	93.8	Very high	89	Confident	20 Å²	20	51.2 Å²	51.2	12%	0.121	31%	0.312	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-126.7	130.8	178.5	178.2	0	0	0	0	109.2	S161 P163 E172 A173	S161-V169 PolarHBondContact N-O 3.38Å; S161-V169 PolarHBondContact O-N 2.88Å; P163-V169 HydrophobicContact CG-CG2 4.22Å; V169-E172 HydrophobicContact CG1-CB 3.68Å; V169-A173 HydrophobicContact CB-CB 3.89Å; V169-A173 HydrophobicContact CG1-CB 3.71Å; V169-A173 HydrophobicContact CG2-CB 4.45Å
170	C	94.4	Very high	89.1	Confident	3 Å²	3	54.2 Å²	54.2	2%	0.02	32%	0.323	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-93.9	112.6	-179.7	-179.4	0	0	0	0	110.9	W72 C79 I160 E172	W72-C170 HydrophobicContact CB-CB 4.24Å; W72-C170 HydrophobicContact CD2-CB 3.68Å; W72-C170 HydrophobicContact CE3-CB 3.42Å; W72-C170 VanDerWaalsContact CE3-CB 3.42Å; W72-C170 HydrophobicContact CG-CB 4.05Å; W72-C170 HydrophobicContact CZ3-CB 4.05Å; C79-C170 WeakPolarHBondContact CA-SG 3.19Å; C79-C170 HydrophobicContact CB-CB 3.87Å; C79-C170 WeakPolarHBondContact CB-SG 3.29Å; C79-C170 WeakPolarHBondContact SG-CA 3.48Å; C79-C170 WeakPolarHBondContact SG-CB 3.21Å; C79-C170 CovalentContact SG-SG 2.03Å; C79-C170 PolarHBondContact SG-SG 2.98Å; I160-C170 HydrophobicContact CD1-CB 4.2Å; C170-E172 PolarHBondContact O-N 2.84Å
171	L	91.1	Very high	89.2	Confident	16 Å²	16	56.8 Å²	56.8	8%	0.084	34%	0.34	C	S	.	.	S	Bend	trans	59.6	-25.6	176	-152.7	80	0	0	0	117.3	V83 F87 L142 G159 A173 W174	V83-L171 HydrophobicContact CG1-CD1 4.49Å; V83-L171 HydrophobicContact CG1-CD2 3.81Å; V83-L171 HydrophobicContact CG2-CB 3.99Å; V83-L171 HydrophobicContact CG2-CD1 4.42Å; V83-L171 HydrophobicContact CG2-CD2 3.98Å; V83-L171 HydrophobicContact CG2-CG 4.36Å; F87-L171 HydrophobicContact CE2-CD2 4.16Å; L142-L171 HydrophobicContact CD1-CD1 3.72Å; G159-L171 PolarHBondContact O-N 3.43Å; L171-A173 VanDerWaalsContact C-N 3.32Å; L171-A173 PolarHBondContact O-N 3.38Å; L171-W174 HydrophobicContact CD1-CD2 4.48Å; L171-W174 HydrophobicContact CD1-CE3 3.54Å; L171-W174 HydrophobicContact CD1-CZ3 3.87Å; L171-W174 HydrophobicContact CG-CE3 4Å; L171-W174 VanDerWaalsContact O-CB 3.32Å; L171-W174 WeakPolarHBondContact O-CB 3.4Å; L171-W174 PolarHBondContact O-N 2.82Å
172	E	87.3	Confident	89.3	Confident	46 Å²	46	55.9 Å²	55.9	22%	0.215	33%	0.334	C	S	.	.	T	Hydrogen-bonded Turn	trans	-67.3	-33	-178.8	-64.6	-65	128.6	0	0	111.8	K62 V169 C170 R258	K62-E172 IonicContact NZ-OE1 2.72Å; V169-E172 HydrophobicContact CG1-CB 3.68Å; C170-E172 PolarHBondContact O-N 2.84Å; E172-R258 IonicContact OE1-CZ 3.71Å; E172-R258 IonicContact OE1-NH2 2.73Å; E172-R258 PolarHBondContact OE1-NH2 3.28Å; E172-R258 IonicContact OE2-CZ 3.54Å; E172-R258 IonicContact OE2-NE 3.87Å; E172-R258 IonicContact OE2-NH2 2.6Å; E172-R258 PolarHBondContact OE2-NH2 2.81Å
173	A	88.3	Confident	89.7	Confident	42 Å²	42	51.8 Å²	51.8	35%	0.347	31%	0.312	S	S	.	.	T	Hydrogen-bonded Turn	trans	-99.4	32	175.7	0	0	0	0	0	112.8	S161 V169 L171	S161-A173 VanDerWaalsContact CB-O 3.3Å; S161-A173 WeakPolarHBondContact CB-O 3.3Å; S161-A173 PolarHBondContact OG-O 2.69Å; V169-A173 HydrophobicContact CB-CB 3.89Å; V169-A173 HydrophobicContact CG1-CB 3.71Å; V169-A173 HydrophobicContact CG2-CB 4.45Å; L171-A173 VanDerWaalsContact C-N 3.32Å; L171-A173 PolarHBondContact O-N 3.38Å
174	W	90.8	Very high	90.2	Very high	14 Å²	14	50.7 Å²	50.7	5%	0.053	30%	0.302	C	S	.	.			trans	-72	131.5	170.5	-175.6	2.2	0	0	0	110	V141 E145 A146 P147 L171 A179 A182	V141-W174 HydrophobicContact CG1-CH2 4.01Å; E145-W174 VanDerWaalsContact C-CZ2 3.49Å; E145-W174 HydrophobicContact CB-CH2 4.5Å; E145-W174 HydrophobicContact CB-CZ2 3.78Å; E145-W174 WeakPolarHBondContact O-CZ2 3.44Å; E145-W174 PolarHBondContact O-NE1 3.19Å; E145-W174 VanDerWaalsContact O-NE1 3.1Å; A146-W174 HydrophobicContact CB-CD2 4.43Å; A146-W174 HydrophobicContact CB-CE3 4.48Å; A146-W174 HydrophobicContact CB-CH2 4.05Å; A146-W174 HydrophobicContact CB-CZ2 4.02Å; A146-W174 HydrophobicContact CB-CZ3 4.28Å; P147-W174 HydrophobicContact CG-CB 4.35Å; P147-W174 HydrophobicContact CG-CG 4.23Å; L171-W174 HydrophobicContact CD1-CD2 4.48Å; L171-W174 HydrophobicContact CD1-CE3 3.54Å; L171-W174 HydrophobicContact CD1-CZ3 3.87Å; L171-W174 HydrophobicContact CG-CE3 4Å; L171-W174 VanDerWaalsContact O-CB 3.32Å; L171-W174 WeakPolarHBondContact O-CB 3.4Å; L171-W174 PolarHBondContact O-N 2.82Å; W174-A179 HydrophobicContact CB-CB 3.96Å; W174-A179 HydrophobicContact CD2-CB 3.69Å; W174-A179 HydrophobicContact CE3-CB 4.09Å; W174-A179 HydrophobicContact CG-CB 3.65Å; W174-A182 HydrophobicContact CH2-CB 3.78Å; W174-A182 HydrophobicContact CZ2-CB 4.26Å; W174-A182 HydrophobicContact CZ3-CB 4.37Å
175	D	90.9	Very high	91.2	Very high	76 Å²	76	45.1 Å²	45.1	41%	0.406	27%	0.27	S	S	.	.			trans	-38.3	118.7	172.3	175.1	52	0	0	0	112.7	N177 S178 A179	D175-N177 PolarHBondContact O-N 2.86Å; D175-N177 WeakPolarHBondContact OD2-CB 3.28Å; D175-N177 PolarHBondContact OD2-N 3.39Å; D175-S178 PolarHBondContact O-N 2.87Å; D175-S178 PolarHBondContact OD2-N 3.42Å; D175-A179 VanDerWaalsContact O-CB 3.25Å; D175-A179 WeakPolarHBondContact O-CB 3.45Å; D175-A179 PolarHBondContact O-N 3.32Å
176	P	91.2	Very high	92.3	Very high	59 Å²	59	39 Å²	39	38%	0.383	24%	0.237	S	C	.	.	H	α-helix	trans	-61.2	-27.5	-173.9	-25.8	34.3	0	0	0	115	S178 R180	P176-S178 VanDerWaalsContact C-N 3.29Å; P176-S178 PolarHBondContact O-N 2.92Å; P176-R180 HydrophobicContact CB-CG 4.5Å; P176-R180 VanDerWaalsContact CB-CZ 3.49Å; P176-R180 WeakPolarHBondContact O-CB 3.47Å; P176-R180 WeakPolarHBondContact O-CD 3.2Å; P176-R180 WeakPolarHBondContact O-CG 3.38Å; P176-R180 PolarHBondContact O-N 3.44Å
177	N	91	Very high	92.9	Very high	121 Å²	121	36.6 Å²	36.6	65%	0.647	21%	0.212	S	C	*	.	H	α-helix	trans	-67.4	-33.4	-178.8	-61.7	-38.6	0	0	0	111.7	D175 P181	D175-N177 PolarHBondContact O-N 2.86Å; D175-N177 WeakPolarHBondContact OD2-CB 3.28Å; D175-N177 PolarHBondContact OD2-N 3.39Å; N177-P181 WeakPolarHBondContact O-CD 3.29Å; N177-P181 VanDerWaalsContact O-CG 3.3Å; N177-P181 WeakPolarHBondContact O-CG 3.49Å
178	S	91.9	Very high	93.2	Very high	43 Å²	43	38.3 Å²	38.3	30%	0.301	22%	0.216	S	C	.	.	H	α-helix	trans	-91.8	-39.6	174.7	-52.3	0	0	0	0	111.6	D175 P176 R180 P181 A182	D175-S178 PolarHBondContact O-N 2.87Å; D175-S178 PolarHBondContact OD2-N 3.42Å; P176-S178 VanDerWaalsContact C-N 3.29Å; P176-S178 PolarHBondContact O-N 2.92Å; S178-R180 PolarHBondContact O-N 3.27Å; S178-P181 WeakPolarHBondContact O-CD 3.29Å; S178-A182 WeakPolarHBondContact O-CB 3.46Å; S178-A182 PolarHBondContact O-N 3.39Å
179	A	92.8	Very high	93.3	Very high	0 Å²	0	39.5 Å²	39.5	0%	0	22%	0.219	C	C	.	.	H	α-helix	trans	-67.4	-37.4	-175.6	0	0	0	0	0	113.7	W174 D175 R183	W174-A179 HydrophobicContact CB-CB 3.96Å; W174-A179 HydrophobicContact CD2-CB 3.69Å; W174-A179 HydrophobicContact CE3-CB 4.09Å; W174-A179 HydrophobicContact CG-CB 3.65Å; D175-A179 VanDerWaalsContact O-CB 3.25Å; D175-A179 WeakPolarHBondContact O-CB 3.45Å; D175-A179 PolarHBondContact O-N 3.32Å; A179-R183 WeakPolarHBondContact O-CB 3.33Å; A179-R183 WeakPolarHBondContact O-CD 3.31Å; A179-R183 WeakPolarHBondContact O-CG 3.38Å; A179-R183 PolarHBondContact O-N 3.49Å
180	R	94.1	Very high	93.4	Very high	63 Å²	63	38.8 Å²	38.8	24%	0.238	22%	0.215	C	C	.	.	H	α-helix	trans	-68.2	-51.1	-177.4	-67.5	169.3	-176.7	143	-2.8	112	P176 S178 A182 R183 L184 S247 F248 P251	P176-R180 HydrophobicContact CB-CG 4.5Å; P176-R180 VanDerWaalsContact CB-CZ 3.49Å; P176-R180 WeakPolarHBondContact O-CB 3.47Å; P176-R180 WeakPolarHBondContact O-CD 3.2Å; P176-R180 WeakPolarHBondContact O-CG 3.38Å; P176-R180 PolarHBondContact O-N 3.44Å; S178-R180 PolarHBondContact O-N 3.27Å; R180-A182 VanDerWaalsContact C-N 3.33Å; R180-A182 PolarHBondContact O-N 2.89Å; R180-R183 PolarHBondContact O-N 3.36Å; R180-L184 WeakPolarHBondContact O-CB 3.38Å; R180-L184 PolarHBondContact O-N 2.91Å; R180-S247 VanDerWaalsContact CD-O 3.31Å; R180-S247 WeakPolarHBondContact CD-O 3.48Å; R180-S247 PolarHBondContact NE-O 3.45Å; R180-F248 HydrophobicContact CB-CD2 4.12Å; R180-P251 PolarHBondContact NH2-O 3.37Å; R180-P251 VanDerWaalsContact NH2-O 3.16Å
181	P	94.9	Very high	93.5	Very high	59 Å²	59	38.9 Å²	38.9	38%	0.383	22%	0.215	S	C	.	.	H	α-helix	trans	-58.3	-42.9	173.8	-22.6	32.3	0	0	0	112.8	N177 S178 R183 L184 S185 F248	N177-P181 WeakPolarHBondContact O-CD 3.29Å; N177-P181 VanDerWaalsContact O-CG 3.3Å; N177-P181 WeakPolarHBondContact O-CG 3.49Å; S178-P181 WeakPolarHBondContact O-CD 3.29Å; P181-R183 PolarHBondContact O-N 2.95Å; P181-L184 PolarHBondContact O-N 2.96Å; P181-S185 PolarHBondContact O-N 3.4Å; P181-F248 HydrophobicContact CB-CE2 4.42Å; P181-F248 HydrophobicContact CG-CE2 4.19Å
182	A	94.9	Very high	93.9	Very high	3 Å²	3	42 Å²	42	3%	0.025	23%	0.228	C	C	.	.	H	α-helix	trans	-55.9	-53.2	175.9	0	0	0	0	0	111.8	V141 W174 S178 R180 L184 S185 F186	V141-A182 HydrophobicContact CG1-CB 3.52Å; W174-A182 HydrophobicContact CH2-CB 3.78Å; W174-A182 HydrophobicContact CZ2-CB 4.26Å; W174-A182 HydrophobicContact CZ3-CB 4.37Å; S178-A182 WeakPolarHBondContact O-CB 3.46Å; S178-A182 PolarHBondContact O-N 3.39Å; R180-A182 VanDerWaalsContact C-N 3.33Å; R180-A182 PolarHBondContact O-N 2.89Å; A182-L184 VanDerWaalsContact C-N 3.35Å; A182-L184 PolarHBondContact O-N 3.29Å; A182-S185 WeakPolarHBondContact O-CB 3.23Å; A182-S185 PolarHBondContact O-N 2.92Å; A182-S185 PolarHBondContact O-OG 3.26Å; A182-F186 WeakPolarHBondContact O-CD2 3.44Å; A182-F186 WeakPolarHBondContact O-CG 3.46Å; A182-F186 PolarHBondContact O-N 2.98Å; A182-F186 VanDerWaalsContact O-N 3.1Å
183	R	95.4	Very high	94.3	Very high	25 Å²	25	44.7 Å²	44.7	9%	0.094	24%	0.242	C	C	.	.	H	α-helix	trans	-62.7	-38.6	178.4	-70.8	167.5	-168.7	173.2	4.1	112.5	A179 R180 P181 F186 S187 N244	A179-R183 WeakPolarHBondContact O-CB 3.33Å; A179-R183 WeakPolarHBondContact O-CD 3.31Å; A179-R183 WeakPolarHBondContact O-CG 3.38Å; A179-R183 PolarHBondContact O-N 3.49Å; R180-R183 PolarHBondContact O-N 3.36Å; P181-R183 PolarHBondContact O-N 2.95Å; R183-F186 PolarHBondContact O-N 3.37Å; R183-S187 PolarHBondContact O-N 2.89Å; R183-S187 PolarHBondContact O-OG 3.14Å; R183-N244 HydrophobicContact CB-CB 4.09Å
184	L	95.7	Very high	94.7	Very high	30 Å²	30	43.1 Å²	43.1	16%	0.157	23%	0.228	C	C	.	.	H	α-helix	trans	-62	-44.3	174.3	179	66.5	0	0	0	111	R180 P181 A182 F186 S187 I188 V245 F248	R180-L184 WeakPolarHBondContact O-CB 3.38Å; R180-L184 PolarHBondContact O-N 2.91Å; P181-L184 PolarHBondContact O-N 2.96Å; A182-L184 VanDerWaalsContact C-N 3.35Å; A182-L184 PolarHBondContact O-N 3.29Å; L184-F186 VanDerWaalsContact C-N 3.3Å; L184-F186 PolarHBondContact O-N 3.09Å; L184-S187 PolarHBondContact O-N 3.49Å; L184-S187 VanDerWaalsContact O-N 3.14Å; L184-I188 HydrophobicContact CD1-CD1 3.95Å; L184-I188 HydrophobicContact CD1-CG1 4.13Å; L184-I188 HydrophobicContact CD2-CD1 4.29Å; L184-I188 HydrophobicContact CG-CD1 3.79Å; L184-I188 HydrophobicContact CG-CG1 4.33Å; L184-I188 WeakPolarHBondContact O-CG1 3.39Å; L184-I188 PolarHBondContact O-N 3.48Å; L184-V245 HydrophobicContact CD1-CG2 3.88Å; L184-F248 HydrophobicContact CB-CD2 4.18Å; L184-F248 HydrophobicContact CB-CG 4.37Å; L184-F248 HydrophobicContact CD2-CB 4.49Å; L184-F248 HydrophobicContact CD2-CD1 3.64Å; L184-F248 HydrophobicContact CD2-CD2 3.77Å; L184-F248 HydrophobicContact CD2-CE1 3.65Å; L184-F248 HydrophobicContact CD2-CE2 3.79Å; L184-F248 HydrophobicContact CD2-CG 3.7Å; L184-F248 HydrophobicContact CD2-CZ 3.73Å; L184-F248 HydrophobicContact CG-CG 4.48Å
185	S	96.6	Very high	95.1	Very high	36 Å²	36	43.8 Å²	43.8	25%	0.252	23%	0.233	S	C	.	.	H	α-helix	trans	-58.9	-42.6	177.6	86.1	0	0	0	0	111.5	H137 P181 A182 L189	H137-S185 PolarHBondContact NE2-OG 2.84Å; H137-S185 VanDerWaalsContact NE2-OG 3.08Å; P181-S185 PolarHBondContact O-N 3.4Å; A182-S185 WeakPolarHBondContact O-CB 3.23Å; A182-S185 PolarHBondContact O-N 2.92Å; A182-S185 PolarHBondContact O-OG 3.26Å; S185-L189 WeakPolarHBondContact O-CB 3.46Å; S185-L189 PolarHBondContact O-N 3.47Å; S185-L189 VanDerWaalsContact O-N 3.08Å
186	F	96.6	Very high	95.4	Very high	16 Å²	16	43.1 Å²	43.1	7%	0.07	24%	0.237	C	C	.	.	H	α-helix	trans	-61.9	-46.2	174.7	-58.5	-29.7	0	0	0	111.1	Y91 H137 M138 V141 A182 R183 L184 L190	Y91-F186 HydrophobicContact CE2-CB 4.32Å; H137-F186 AromaticContact CD2-CD1 3.39Å; H137-F186 WeakPolarHBondContact CD2-CD1 3.34Å; H137-F186 AromaticContact CD2-CE1 3.65Å; H137-F186 AromaticContact NE2-CD1 3.47Å; H137-F186 WeakPolarHBondContact NE2-CD1 3.48Å; H137-F186 AromaticContact NE2-CE1 3.75Å; M138-F186 HydrophobicContact CE-CD2 4.45Å; M138-F186 HydrophobicContact CE-CG 4.42Å; M138-F186 HydrophobicContact CG-CE1 4.32Å; M138-F186 HydrophobicContact SD-CD1 4.41Å; M138-F186 HydrophobicContact SD-CD2 4.21Å; M138-F186 HydrophobicContact SD-CE1 4.15Å; M138-F186 HydrophobicContact SD-CE2 3.94Å; M138-F186 HydrophobicContact SD-CG 4.44Å; M138-F186 HydrophobicContact SD-CZ 3.89Å; V141-F186 HydrophobicContact CB-CE1 3.86Å; V141-F186 HydrophobicContact CB-CZ 3.66Å; V141-F186 HydrophobicContact CG1-CE1 4.01Å; V141-F186 HydrophobicContact CG1-CE2 4.28Å; V141-F186 HydrophobicContact CG1-CZ 3.46Å; V141-F186 VanDerWaalsContact CG1-CZ 3.46Å; V141-F186 HydrophobicContact CG2-CE1 3.88Å; V141-F186 HydrophobicContact CG2-CZ 4.18Å; A182-F186 WeakPolarHBondContact O-CD2 3.44Å; A182-F186 WeakPolarHBondContact O-CG 3.46Å; A182-F186 PolarHBondContact O-N 2.98Å; A182-F186 VanDerWaalsContact O-N 3.1Å; R183-F186 PolarHBondContact O-N 3.37Å; L184-F186 VanDerWaalsContact C-N 3.3Å; L184-F186 PolarHBondContact O-N 3.09Å; F186-L190 WeakPolarHBondContact O-CA 3.33Å; F186-L190 WeakPolarHBondContact O-CB 3.06Å; F186-L190 PolarHBondContact O-N 3.25Å
187	S	96.8	Very high	95.7	Very high	0 Å²	0	43.2 Å²	43.2	0%	0	23%	0.234	C	C	.	.	H	α-helix	trans	-63.7	-43.4	179.4	-68.6	0	0	0	0	113	R183 L184 F191 F192 N241 N244	R183-S187 PolarHBondContact O-N 2.89Å; R183-S187 PolarHBondContact O-OG 3.14Å; L184-S187 PolarHBondContact O-N 3.49Å; L184-S187 VanDerWaalsContact O-N 3.14Å; S187-F191 WeakPolarHBondContact O-CA 3.2Å; S187-F191 WeakPolarHBondContact O-CB 3.41Å; S187-F191 PolarHBondContact O-N 3.18Å; S187-F191 VanDerWaalsContact O-N 3.14Å; S187-F192 WeakPolarHBondContact O-CD2 3.33Å; S187-F192 PolarHBondContact O-N 3.33Å; S187-N241 WeakPolarHBondContact CA-OD1 3.43Å; S187-N241 WeakPolarHBondContact CB-OD1 3.3Å; S187-N241 PolarHBondContact OG-OD1 3.08Å; S187-N244 WeakPolarHBondContact OG-CB 3.04Å; S187-N244 PolarHBondContact OG-ND2 3.19Å; S187-N244 VanDerWaalsContact OG-ND2 3.1Å
188	I	95.2	Very high	96	Very high	96 Å²	96	37.4 Å²	37.4	49%	0.492	20%	0.203	S	C	.	.	I	π-helix	trans	-62.9	-54.6	178.8	-67.7	172.1	0	0	0	110.6	L184 M193	L184-I188 HydrophobicContact CD1-CD1 3.95Å; L184-I188 HydrophobicContact CD1-CG1 4.13Å; L184-I188 HydrophobicContact CD2-CD1 4.29Å; L184-I188 HydrophobicContact CG-CD1 3.79Å; L184-I188 HydrophobicContact CG-CG1 4.33Å; L184-I188 WeakPolarHBondContact O-CG1 3.39Å; L184-I188 PolarHBondContact O-N 3.48Å; I188-M193 PolarHBondContact O-N 2.94Å
189	L	95	Very high	96.2	Very high	61 Å²	61	37 Å²	37	32%	0.319	20%	0.202	S	C	.	.	I	π-helix	trans	-77.3	-41.8	-171.2	-175.4	60.2	0	0	0	112.7	L133 S185	L133-L189 HydrophobicContact CD1-CD2 4.14Å; S185-L189 WeakPolarHBondContact O-CB 3.46Å; S185-L189 PolarHBondContact O-N 3.47Å; S185-L189 VanDerWaalsContact O-N 3.08Å
190	L	96.4	Very high	96.4	Very high	6 Å²	6	43.2 Å²	43.2	3%	0.031	23%	0.23	C	C	.	.	I	π-helix	trans	-103.8	-7.4	-168.1	-52.5	178.8	0	0	0	113.6	Y91 L133 V134 M138 F186 P194	Y91-L190 HydrophobicContact CD1-CB 3.27Å; Y91-L190 HydrophobicContact CD1-CD1 4.27Å; Y91-L190 HydrophobicContact CD1-CG 4.41Å; Y91-L190 HydrophobicContact CD2-CD1 4.48Å; Y91-L190 HydrophobicContact CE1-CB 3.9Å; Y91-L190 HydrophobicContact CG-CB 3.8Å; Y91-L190 HydrophobicContact CG-CD1 4.02Å; L133-L190 HydrophobicContact CD2-CD2 4.25Å; L133-L190 HydrophobicContact CG-CD2 4.17Å; V134-L190 HydrophobicContact CG1-CD1 4.39Å; V134-L190 HydrophobicContact CG2-CD1 4.38Å; V134-L190 HydrophobicContact CG2-CD2 3.93Å; M138-L190 HydrophobicContact CE-CD1 4.26Å; F186-L190 WeakPolarHBondContact O-CA 3.33Å; F186-L190 WeakPolarHBondContact O-CB 3.06Å; F186-L190 PolarHBondContact O-N 3.25Å; L190-P194 WeakPolarHBondContact O-CG 3.49Å
191	F	97.8	Very high	96.4	Very high	5 Å²	5	40.4 Å²	40.4	2%	0.022	22%	0.22	C	C	.	.	I	π-helix	trans	-122.5	-56.8	174.7	171.9	-100.8	0	0	0	113.5	Y91 S187 M193 P194 L195 L233 L237 G238 N241	Y91-F191 HydrophobicContact CE1-CB 4.19Å; S187-F191 WeakPolarHBondContact O-CA 3.2Å; S187-F191 WeakPolarHBondContact O-CB 3.41Å; S187-F191 PolarHBondContact O-N 3.18Å; S187-F191 VanDerWaalsContact O-N 3.14Å; F191-M193 PolarHBondContact O-N 3.14Å; F191-P194 WeakPolarHBondContact O-CD 3.43Å; F191-L195 HydrophobicContact CE1-CD2 3.95Å; F191-L195 HydrophobicContact CZ-CD2 3.91Å; F191-L195 VanDerWaalsContact O-CB 3.28Å; F191-L195 WeakPolarHBondContact O-CB 3.44Å; F191-L195 PolarHBondContact O-N 2.84Å; F191-L233 HydrophobicContact CE2-CB 4.34Å; F191-L233 WeakPolarHBondContact CE2-O 3.37Å; F191-L237 HydrophobicContact CD2-CB 3.75Å; F191-L237 HydrophobicContact CD2-CD2 4.36Å; F191-L237 HydrophobicContact CE2-CB 3.67Å; F191-G238 VanDerWaalsContact CZ-CA 3.5Å; F191-N241 HydrophobicContact CB-CB 4.03Å; F191-N241 WeakPolarHBondContact CB-OD1 3.32Å; F191-N241 HydrophobicContact CD1-CB 3.34Å; F191-N241 HydrophobicContact CD2-CB 4.31Å; F191-N241 WeakPolarHBondContact CD2-ND2 3.23Å; F191-N241 HydrophobicContact CE1-CB 3.83Å; F191-N241 HydrophobicContact CG-CB 3.62Å; F191-N241 WeakPolarHBondContact CG-ND2 3.25Å
192	F	97.9	Very high	96.3	Very high	81 Å²	81	41 Å²	41	36%	0.355	22%	0.215	S	C	.	.	I	π-helix	trans	-66.7	-37.2	-174.8	-72.8	-69	0	0	0	112.7	S187 L195 A196 V245	S187-F192 WeakPolarHBondContact O-CD2 3.33Å; S187-F192 PolarHBondContact O-N 3.33Å; F192-L195 HydrophobicContact CD1-CD2 4.31Å; F192-L195 PolarHBondContact O-N 2.68Å; F192-A196 WeakPolarHBondContact O-CB 3.4Å; F192-A196 PolarHBondContact O-N 2.99Å; F192-V245 HydrophobicContact CE2-CG2 3.62Å; F192-V245 HydrophobicContact CZ-CG2 3.94Å
193	M	96.3	Very high	96.3	Very high	102 Å²	102	43.9 Å²	43.9	50%	0.502	23%	0.232	S	C	.	.	H	α-helix	trans	-63.8	-51.1	174.4	-179.3	-108.2	-167.1	0	0	112	I188 F191 L195 A196 I197	I188-M193 PolarHBondContact O-N 2.94Å; F191-M193 PolarHBondContact O-N 3.14Å; M193-L195 VanDerWaalsContact C-N 3.33Å; M193-L195 PolarHBondContact O-N 3.23Å; M193-A196 PolarHBondContact O-N 3.47Å; M193-I197 HydrophobicContact CE-CD1 3.94Å; M193-I197 HydrophobicContact CG-CD1 4.32Å; M193-I197 WeakPolarHBondContact O-CG1 3.37Å; M193-I197 PolarHBondContact O-N 3.28Å; M193-I197 VanDerWaalsContact O-N 3.1Å; M193-I197 HydrophobicContact SD-CD1 3.95Å
194	P	97.3	Very high	96.1	Very high	9 Å²	9	43.1 Å²	43.1	6%	0.058	23%	0.232	C	C	.	.	H	α-helix	trans	-57.3	-37.9	169.7	-30.7	37.7	0	0	0	115.1	A98 L190 F191 T198	A98-P194 HydrophobicContact CB-CB 3.93Å; L190-P194 WeakPolarHBondContact O-CG 3.49Å; F191-P194 WeakPolarHBondContact O-CD 3.43Å; P194-T198 WeakPolarHBondContact O-CB 3.21Å; P194-T198 PolarHBondContact O-N 3.18Å; P194-T198 PolarHBondContact O-OG1 2.8Å
195	L	98.1	Very high	95.9	Very high	29 Å²	29	42 Å²	42	15%	0.152	23%	0.227	C	C	.	.	H	α-helix	trans	-63.3	-47.6	177.5	179.7	66.8	0	0	0	111.4	F191 F192 M193 I197 T198 A199 L230 L233 L234	F191-L195 HydrophobicContact CE1-CD2 3.95Å; F191-L195 HydrophobicContact CZ-CD2 3.91Å; F191-L195 VanDerWaalsContact O-CB 3.28Å; F191-L195 WeakPolarHBondContact O-CB 3.44Å; F191-L195 PolarHBondContact O-N 2.84Å; F192-L195 HydrophobicContact CD1-CD2 4.31Å; F192-L195 PolarHBondContact O-N 2.68Å; M193-L195 VanDerWaalsContact C-N 3.33Å; M193-L195 PolarHBondContact O-N 3.23Å; L195-I197 PolarHBondContact O-N 3.41Å; L195-T198 PolarHBondContact O-N 3.25Å; L195-A199 WeakPolarHBondContact O-CB 3.36Å; L195-A199 PolarHBondContact O-N 2.95Å; L195-L230 HydrophobicContact CD1-CD1 3.62Å; L195-L233 HydrophobicContact CD1-CB 3.97Å; L195-L233 HydrophobicContact CD1-CD1 4.23Å; L195-L234 HydrophobicContact CD1-CD2 3.95Å; L195-L234 HydrophobicContact CD1-CG 4.27Å; L195-L234 HydrophobicContact CD2-CD2 4.39Å
196	A	98.2	Very high	95.6	Very high	61 Å²	61	43.2 Å²	43.2	50%	0.504	23%	0.23	S	C	.	.	H	α-helix	trans	-61	-44.8	178.2	0	0	0	0	0	111.6	F192 M193 T198 A199 F200	F192-A196 WeakPolarHBondContact O-CB 3.4Å; F192-A196 PolarHBondContact O-N 2.99Å; M193-A196 PolarHBondContact O-N 3.47Å; A196-T198 VanDerWaalsContact C-N 3.35Å; A196-T198 PolarHBondContact O-N 2.82Å; A196-A199 PolarHBondContact O-N 3.39Å; A196-F200 WeakPolarHBondContact O-CB 3.35Å; A196-F200 PolarHBondContact O-N 3.29Å
197	I	97.1	Very high	95.3	Very high	61 Å²	61	50.7 Å²	50.7	31%	0.313	26%	0.258	S	S	.	.	H	α-helix	trans	-59.5	-47.3	175.2	-66.2	166.9	0	0	0	110.3	A98 M193 L195 F200 C201	A98-I197 HydrophobicContact CB-CB 4.22Å; A98-I197 HydrophobicContact CB-CG2 4.05Å; M193-I197 HydrophobicContact CE-CD1 3.94Å; M193-I197 HydrophobicContact CG-CD1 4.32Å; M193-I197 WeakPolarHBondContact O-CG1 3.37Å; M193-I197 PolarHBondContact O-N 3.28Å; M193-I197 VanDerWaalsContact O-N 3.1Å; M193-I197 HydrophobicContact SD-CD1 3.95Å; L195-I197 PolarHBondContact O-N 3.41Å; I197-F200 PolarHBondContact O-N 2.8Å; I197-C201 WeakPolarHBondContact O-CB 3.47Å; I197-C201 PolarHBondContact O-N 2.98Å; I197-C201 PolarHBondContact O-SG 3.29Å
198	T	96.3	Very high	94.9	Very high	0 Å²	0	51.8 Å²	51.8	0%	0	27%	0.267	C	S	.	.	H	α-helix	trans	-63.7	-44.1	-178.6	-57.7	0	0	0	0	111.6	A98 P194 L195 A196 C201 Y202 A229 L230 L233	A98-T198 WeakPolarHBondContact CA-OG1 3.23Å; P194-T198 WeakPolarHBondContact O-CB 3.21Å; P194-T198 PolarHBondContact O-N 3.18Å; P194-T198 PolarHBondContact O-OG1 2.8Å; L195-T198 PolarHBondContact O-N 3.25Å; A196-T198 VanDerWaalsContact C-N 3.35Å; A196-T198 PolarHBondContact O-N 2.82Å; T198-C201 PolarHBondContact O-N 3.36Å; T198-Y202 WeakPolarHBondContact O-CB 3.35Å; T198-Y202 PolarHBondContact O-N 2.73Å; T198-A229 HydrophobicContact CG2-CB 4.08Å; T198-L230 HydrophobicContact CG2-CB 4.01Å; T198-L230 HydrophobicContact CG2-CD1 4.31Å; T198-L233 HydrophobicContact CG2-CD1 4Å; T198-L233 WeakPolarHBondContact OG1-CD1 3.17Å
199	A	97	Very high	94.5	Very high	34 Å²	34	47.9 Å²	47.9	28%	0.281	25%	0.247	S	C	.	.	H	α-helix	trans	-63.1	-45	176.7	0	0	0	0	0	111.9	L195 A196 C201 Y202 V203 L230	L195-A199 WeakPolarHBondContact O-CB 3.36Å; L195-A199 PolarHBondContact O-N 2.95Å; A196-A199 PolarHBondContact O-N 3.39Å; A199-C201 VanDerWaalsContact C-N 3.35Å; A199-C201 PolarHBondContact O-N 3.37Å; A199-Y202 PolarHBondContact O-N 2.77Å; A199-V203 WeakPolarHBondContact O-CG2 3.27Å; A199-V203 PolarHBondContact O-N 2.86Å; A199-L230 HydrophobicContact CB-CD1 4.17Å
200	F	96.8	Very high	94.2	Very high	130 Å²	130	49.8 Å²	49.8	57%	0.57	26%	0.261	S	S	*	.	H	α-helix	trans	-58.3	-47.4	174.4	176.4	-95.5	0	0	0	111.4	Y105 A196 I197 Y202 V203 G204	Y105-F200 AromaticContact CE1-CE1 3.92Å; Y105-F200 HydrophobicContact CE1-CE1 3.92Å; A196-F200 WeakPolarHBondContact O-CB 3.35Å; A196-F200 PolarHBondContact O-N 3.29Å; I197-F200 PolarHBondContact O-N 2.8Å; F200-Y202 VanDerWaalsContact C-N 3.32Å; F200-Y202 PolarHBondContact O-N 3.29Å; F200-V203 PolarHBondContact O-N 3.06Å; F200-G204 PolarHBondContact O-N 2.84Å
201	C	94.1	Very high	93.8	Very high	5 Å²	5	57.6 Å²	57.6	3%	0.034	30%	0.297	C	S	.	.	H	α-helix	trans	-64	-36.7	178.3	-67.2	0	0	0	0	112.1	A102 Y105 I197 T198 A199 C205	A102-C201 WeakPolarHBondContact CA-SG 3.33Å; Y105-C201 HydrophobicContact CG-CB 4.48Å; I197-C201 WeakPolarHBondContact O-CB 3.47Å; I197-C201 PolarHBondContact O-N 2.98Å; I197-C201 PolarHBondContact O-SG 3.29Å; T198-C201 PolarHBondContact O-N 3.36Å; A199-C201 VanDerWaalsContact C-N 3.35Å; A199-C201 PolarHBondContact O-N 3.37Å; C201-C205 WeakPolarHBondContact O-CB 3.4Å; C201-C205 PolarHBondContact O-N 3.24Å; C201-C205 PolarHBondContact O-SG 3.03Å
202	Y	93.6	Very high	93.2	Very high	72 Å²	72	58.8 Å²	58.8	28%	0.282	31%	0.306	S	S	.	.	H	α-helix	trans	-63.7	-51.2	176.5	175	-112.2	0	0	0	111.4	T198 A199 F200 G204 C205 L206 A226 L230	T198-Y202 WeakPolarHBondContact O-CB 3.35Å; T198-Y202 PolarHBondContact O-N 2.73Å; A199-Y202 PolarHBondContact O-N 2.77Å; F200-Y202 VanDerWaalsContact C-N 3.32Å; F200-Y202 PolarHBondContact O-N 3.29Å; Y202-G204 VanDerWaalsContact C-N 3.32Å; Y202-G204 PolarHBondContact O-N 2.03Å; Y202-C205 WeakPolarHBondContact O-CB 3.38Å; Y202-C205 PolarHBondContact O-N 3.13Å; Y202-L206 HydrophobicContact CD1-CD1 4.31Å; Y202-L206 HydrophobicContact CE1-CD1 3.69Å; Y202-L206 HydrophobicContact CE1-CG 4.44Å; Y202-L206 HydrophobicContact CE2-CD1 4.22Å; Y202-L206 HydrophobicContact CE2-CD2 4.27Å; Y202-L206 HydrophobicContact CE2-CG 4.21Å; Y202-L206 WeakPolarHBondContact O-CG 3.43Å; Y202-L206 PolarHBondContact O-N 3.15Å; Y202-A226 HydrophobicContact CD2-CB 3.97Å; Y202-L230 HydrophobicContact CD1-CD2 3.92Å; Y202-L230 HydrophobicContact CG-CD2 4.22Å
203	V	94.6	Very high	92.6	Very high	62 Å²	62	59.3 Å²	59.3	38%	0.376	33%	0.334	S	S	.	.	H	α-helix	trans	-60.2	-44.1	176.6	175	0	0	0	0	110.8	A199 F200 C205 L206 R207	A199-V203 WeakPolarHBondContact O-CG2 3.27Å; A199-V203 PolarHBondContact O-N 2.86Å; F200-V203 PolarHBondContact O-N 3.06Å; V203-C205 PolarHBondContact O-N 2.89Å; V203-L206 PolarHBondContact O-N 3.22Å; V203-R207 WeakPolarHBondContact O-CG 3.4Å; V203-R207 PolarHBondContact O-N 3.08Å
204	G	91.8	Very high	92	Very high	9 Å²	9	57.3 Å²	57.3	9%	0.093	33%	0.325	C	S	.	.	H	α-helix	trans	-60	-43.2	175.6	0	0	0	0	0	113	Y105 F200 Y202 R207 A208	Y105-G204 VanDerWaalsContact CD2-C 3.48Å; Y105-G204 VanDerWaalsContact CE2-CA 3.48Å; F200-G204 PolarHBondContact O-N 2.84Å; Y202-G204 VanDerWaalsContact C-N 3.32Å; Y202-G204 PolarHBondContact O-N 2.03Å; G204-R207 PolarHBondContact O-N 2.78Å; G204-A208 WeakPolarHBondContact O-CB 3.25Å; G204-A208 PolarHBondContact O-N 3.29Å
205	C	89.9	Confident	91.6	Very high	8 Å²	8	60.3 Å²	60.3	5%	0.054	35%	0.346	C	S	.	.	H	α-helix	trans	-59.3	-47	173.8	-75.1	0	0	0	0	111.3	Y105 C201 Y202 V203 R207 A208 L209 A226	Y105-C205 WeakPolarHBondContact CA-SG 3.48Å; C201-C205 WeakPolarHBondContact O-CB 3.4Å; C201-C205 PolarHBondContact O-N 3.24Å; C201-C205 PolarHBondContact O-SG 3.03Å; Y202-C205 WeakPolarHBondContact O-CB 3.38Å; Y202-C205 PolarHBondContact O-N 3.13Å; V203-C205 PolarHBondContact O-N 2.89Å; C205-R207 PolarHBondContact O-N 3.18Å; C205-A208 PolarHBondContact O-N 2.65Å; C205-L209 WeakPolarHBondContact O-CB 3.13Å; C205-L209 WeakPolarHBondContact O-CG 3.36Å; C205-L209 PolarHBondContact O-N 2.82Å; C205-A226 HydrophobicContact CB-CB 4.21Å
206	L	90.1	Very high	91.1	Very high	61 Å²	61	66 Å²	66	32%	0.319	37%	0.371	S	S	.	.	H	α-helix	trans	-60.1	-46.7	179.2	-69	-177.5	0	0	0	111.5	Y202 V203 A208 L209 V210 A223	Y202-L206 HydrophobicContact CD1-CD1 4.31Å; Y202-L206 HydrophobicContact CE1-CD1 3.69Å; Y202-L206 HydrophobicContact CE1-CG 4.44Å; Y202-L206 HydrophobicContact CE2-CD1 4.22Å; Y202-L206 HydrophobicContact CE2-CD2 4.27Å; Y202-L206 HydrophobicContact CE2-CG 4.21Å; Y202-L206 WeakPolarHBondContact O-CG 3.43Å; Y202-L206 PolarHBondContact O-N 3.15Å; V203-L206 PolarHBondContact O-N 3.22Å; L206-A208 PolarHBondContact O-N 2.81Å; L206-L209 PolarHBondContact O-N 3.37Å; L206-V210 WeakPolarHBondContact O-CG2 3.46Å; L206-V210 PolarHBondContact O-N 3.41Å; L206-A223 HydrophobicContact CD2-CB 3.79Å
207	R	91.8	Very high	90.5	Very high	172 Å²	172	71.5 Å²	71.5	65%	0.649	38%	0.384	S	S	*	.	H	α-helix	trans	-58.7	-49.1	176.7	-69.7	176.8	-177.4	169.3	1.2	111.5	V203 G204 C205 L209 V210 H211	V203-R207 WeakPolarHBondContact O-CG 3.4Å; V203-R207 PolarHBondContact O-N 3.08Å; G204-R207 PolarHBondContact O-N 2.78Å; C205-R207 PolarHBondContact O-N 3.18Å; R207-L209 VanDerWaalsContact C-N 3.3Å; R207-L209 PolarHBondContact O-N 3.05Å; R207-V210 PolarHBondContact O-N 2.93Å; R207-H211 PolarHBondContact O-CD2 3.44Å; R207-H211 PolarHBondContact O-N 3.31Å
208	A	88.3	Confident	89.9	Confident	23 Å²	23	76.1 Å²	76.1	19%	0.19	40%	0.398	C	S	.	.	H	α-helix	trans	-61.5	-38.6	177.8	0	0	0	0	0	112.2	A108 A109 G204 C205 L206 S212	A108-A208 HydrophobicContact CB-CB 4.36Å; A109-A208 HydrophobicContact CB-CB 4.21Å; G204-A208 WeakPolarHBondContact O-CB 3.25Å; G204-A208 PolarHBondContact O-N 3.29Å; C205-A208 PolarHBondContact O-N 2.65Å; L206-A208 PolarHBondContact O-N 2.81Å; A208-S212 WeakPolarHBondContact O-CB 3.39Å; A208-S212 PolarHBondContact O-N 3.1Å; A208-S212 VanDerWaalsContact O-N 3.11Å
209	L	87.3	Confident	89.4	Confident	14 Å²	14	78.6 Å²	78.6	7%	0.073	41%	0.408	C	S	.	.	H	α-helix	trans	-68.7	-39.1	178.2	-73.3	171.3	0	0	0	112.4	C205 L206 R207 H211 S212 L214 K219 A222 A223	C205-L209 WeakPolarHBondContact O-CB 3.13Å; C205-L209 WeakPolarHBondContact O-CG 3.36Å; C205-L209 PolarHBondContact O-N 2.82Å; L206-L209 PolarHBondContact O-N 3.37Å; R207-L209 VanDerWaalsContact C-N 3.3Å; R207-L209 PolarHBondContact O-N 3.05Å; L209-H211 VanDerWaalsContact C-N 3.32Å; L209-H211 PolarHBondContact O-N 2.76Å; L209-S212 WeakPolarHBondContact O-CB 3.37Å; L209-S212 PolarHBondContact O-N 2.87Å; L209-S212 VanDerWaalsContact O-N 3.13Å; L209-S212 PolarHBondContact O-OG 3.31Å; L209-L214 HydrophobicContact CD2-CD1 4.11Å; L209-K219 HydrophobicContact CD2-CG 4.47Å; L209-K219 WeakPolarHBondContact O-CD 3.32Å; L209-K219 WeakPolarHBondContact O-CE 3.32Å; L209-K219 PolarHBondContact O-NZ 2.86Å; L209-A222 HydrophobicContact CD1-CB 3.77Å; L209-A222 HydrophobicContact CD2-CB 3.82Å; L209-A222 HydrophobicContact CG-CB 4.43Å; L209-A223 HydrophobicContact CD1-CB 4.17Å
210	V	88.4	Confident	88.8	Confident	102 Å²	102	82.3 Å²	82.3	62%	0.618	42%	0.423	S	S	*	.	H	α-helix	trans	-56.8	-48.6	176.2	167.8	0	0	0	0	110.1	L206 R207 S212 K219	L206-V210 WeakPolarHBondContact O-CG2 3.46Å; L206-V210 PolarHBondContact O-N 3.41Å; R207-V210 PolarHBondContact O-N 2.93Å; V210-S212 VanDerWaalsContact C-N 3.27Å; V210-S212 PolarHBondContact O-N 3.3Å; V210-K219 PolarHBondContact O-NZ 3.04Å; V210-K219 VanDerWaalsContact O-NZ 3.08Å
211	H	86.6	Confident	88.1	Confident	169 Å²	169	82.9 Å²	82.9	78%	0.782	42%	0.421	S	S	*	.	T	Hydrogen-bonded Turn	trans	-78.5	-3.5	179.3	-63.4	-69.5	0	0	0	114.7	R207 L209	R207-H211 PolarHBondContact O-CD2 3.44Å; R207-H211 PolarHBondContact O-N 3.31Å; L209-H211 VanDerWaalsContact C-N 3.32Å; L209-H211 PolarHBondContact O-N 2.76Å
212	S	85.1	Confident	87.4	Confident	31 Å²	31	84.6 Å²	84.6	22%	0.217	44%	0.436	C	S	.	.	S	Bend	trans	-79.8	146.5	178.7	74.8	0	0	0	0	112.8	A208 L209 V210 L214 K219	A208-S212 WeakPolarHBondContact O-CB 3.39Å; A208-S212 PolarHBondContact O-N 3.1Å; A208-S212 VanDerWaalsContact O-N 3.11Å; L209-S212 WeakPolarHBondContact O-CB 3.37Å; L209-S212 PolarHBondContact O-N 2.87Å; L209-S212 VanDerWaalsContact O-N 3.13Å; L209-S212 PolarHBondContact O-OG 3.31Å; V210-S212 VanDerWaalsContact C-N 3.27Å; V210-S212 PolarHBondContact O-N 3.3Å; S212-L214 PolarHBondContact O-N 3.41Å; S212-K219 WeakPolarHBondContact O-CE 3.3Å; S212-K219 PolarHBondContact O-NZ 2.96Å; S212-K219 WeakPolarHBondContact OG-CE 3.49Å
213	G	85.6	Confident	86.9	Confident	91 Å²	91	82.1 Å²	82.1	94%	0.938	43%	0.43	S	S	*	.			trans	-77.1	16.9	170.3	0	0	0	0	0	114.7
214	L	84.4	Confident	86.4	Confident	61 Å²	61	86.6 Å²	86.6	32%	0.319	44%	0.44	S	S	.	.			trans	-73.8	148.9	-178.7	-69	172.9	0	0	0	112	L209 S212 R218 K219	L209-L214 HydrophobicContact CD2-CD1 4.11Å; S212-L214 PolarHBondContact O-N 3.41Å; L214-R218 HydrophobicContact CB-CB 4.41Å; L214-K219 HydrophobicContact CB-CG 3.97Å; L214-K219 WeakPolarHBondContact O-CE 3.14Å
215	S	89.1	Confident	85.7	Confident	72 Å²	72	87.7 Å²	87.7	50%	0.503	45%	0.445	S	S	.	.			trans	-58.4	145.7	169.6	172.5	0	0	0	0	111.8	K217 R218 K219	S215-K217 VanDerWaalsContact C-N 3.26Å; S215-K217 PolarHBondContact O-N 2.98Å; S215-K217 VanDerWaalsContact O-N 3.17Å; S215-R218 WeakPolarHBondContact O-CA 3.4Å; S215-R218 WeakPolarHBondContact O-CB 3.22Å; S215-R218 PolarHBondContact O-N 3.47Å; S215-K219 PolarHBondContact O-N 3.44Å
216	H	87.6	Confident	85.1	Confident	147 Å²	147	87.5 Å²	87.5	68%	0.681	44%	0.444	S	S	*	.	H	α-helix	trans	-48.2	-44.4	178.3	-173.4	-96.6	0	0	0	113.2	R218 K219 L220	H216-R218 VanDerWaalsContact C-N 3.29Å; H216-R218 PolarHBondContact O-N 3.21Å; H216-K219 PolarHBondContact O-N 3.19Å; H216-L220 PolarHBondContact O-N 3.13Å
217	K	85.7	Confident	85.1	Confident	177 Å²	177	85.2 Å²	85.2	77%	0.77	44%	0.435	S	S	*	.	H	α-helix	trans	-59.6	-38.3	178.1	-68.8	-175.2	178.4	-178.8	0	112.7	S215 R221	S215-K217 VanDerWaalsContact C-N 3.26Å; S215-K217 PolarHBondContact O-N 2.98Å; S215-K217 VanDerWaalsContact O-N 3.17Å; K217-R221 WeakPolarHBondContact O-CB 3.48Å; K217-R221 PolarHBondContact O-N 3.49Å; K217-R221 VanDerWaalsContact O-N 3.14Å
218	R	83.1	Confident	85.1	Confident	159 Å²	159	77 Å²	77	60%	0.6	40%	0.404	S	S	*	.	H	α-helix	trans	-74.2	-38.5	178.6	-66.5	-176.5	-179.9	-174.6	0.6	111.4	L214 S215 H216 R221 A222	L214-R218 HydrophobicContact CB-CB 4.41Å; S215-R218 WeakPolarHBondContact O-CA 3.4Å; S215-R218 WeakPolarHBondContact O-CB 3.22Å; S215-R218 PolarHBondContact O-N 3.47Å; H216-R218 VanDerWaalsContact C-N 3.29Å; H216-R218 PolarHBondContact O-N 3.21Å; R218-R221 PolarHBondContact O-N 3.45Å; R218-A222 WeakPolarHBondContact O-CB 3.46Å; R218-A222 PolarHBondContact O-N 3.31Å
219	K	85.9	Confident	85.3	Confident	52 Å²	52	76 Å²	76	23%	0.226	40%	0.395	C	S	.	.	H	α-helix	trans	-60.8	-48.5	173.8	-63.8	-170.1	-174.1	-161.7	0	111.1	L209 V210 S212 L214 S215 H216 R221 A222 A223	L209-K219 HydrophobicContact CD2-CG 4.47Å; L209-K219 WeakPolarHBondContact O-CD 3.32Å; L209-K219 WeakPolarHBondContact O-CE 3.32Å; L209-K219 PolarHBondContact O-NZ 2.86Å; V210-K219 PolarHBondContact O-NZ 3.04Å; V210-K219 VanDerWaalsContact O-NZ 3.08Å; S212-K219 WeakPolarHBondContact O-CE 3.3Å; S212-K219 PolarHBondContact O-NZ 2.96Å; S212-K219 WeakPolarHBondContact OG-CE 3.49Å; L214-K219 HydrophobicContact CB-CG 3.97Å; L214-K219 WeakPolarHBondContact O-CE 3.14Å; S215-K219 PolarHBondContact O-N 3.44Å; H216-K219 PolarHBondContact O-N 3.19Å; K219-R221 VanDerWaalsContact C-N 3.35Å; K219-R221 PolarHBondContact O-N 3.15Å; K219-A222 PolarHBondContact O-N 3.1Å; K219-A223 WeakPolarHBondContact O-CB 3.47Å; K219-A223 PolarHBondContact O-N 3.17Å
220	L	84.5	Confident	85.7	Confident	112 Å²	112	76.6 Å²	76.6	59%	0.586	40%	0.399	S	S	*	.	H	α-helix	trans	-60	-44.4	178.4	-171.4	69.3	0	0	0	111.7	H216 A222 A223 W224	H216-L220 PolarHBondContact O-N 3.13Å; L220-A222 PolarHBondContact O-N 3.44Å; L220-A223 PolarHBondContact O-N 2.81Å; L220-W224 WeakPolarHBondContact O-CB 3.18Å; L220-W224 PolarHBondContact O-N 3.28Å
221	R	82.1	Confident	86.1	Confident	142 Å²	142	74.7 Å²	74.7	54%	0.536	39%	0.385	S	S	.	.	H	α-helix	trans	-61.5	-44.3	176.4	-171.3	177.8	-173.7	175.5	5.3	112.2	K217 R218 K219 W224 V225	K217-R221 WeakPolarHBondContact O-CB 3.48Å; K217-R221 PolarHBondContact O-N 3.49Å; K217-R221 VanDerWaalsContact O-N 3.14Å; R218-R221 PolarHBondContact O-N 3.45Å; K219-R221 VanDerWaalsContact C-N 3.35Å; K219-R221 PolarHBondContact O-N 3.15Å; R221-W224 PolarHBondContact O-N 3.31Å; R221-V225 WeakPolarHBondContact O-CB 3.48Å; R221-V225 WeakPolarHBondContact O-CG2 3.41Å; R221-V225 PolarHBondContact O-N 3.26Å
222	A	79.9	Confident	86.5	Confident	41 Å²	41	66.7 Å²	66.7	34%	0.339	35%	0.348	S	S	.	.	H	α-helix	trans	-66.3	-41.6	178.7	0	0	0	0	0	112.1	L209 R218 K219 L220 V225 A226	L209-A222 HydrophobicContact CD1-CB 3.77Å; L209-A222 HydrophobicContact CD2-CB 3.82Å; L209-A222 HydrophobicContact CG-CB 4.43Å; R218-A222 WeakPolarHBondContact O-CB 3.46Å; R218-A222 PolarHBondContact O-N 3.31Å; K219-A222 PolarHBondContact O-N 3.1Å; L220-A222 PolarHBondContact O-N 3.44Å; A222-V225 PolarHBondContact O-N 3.01Å; A222-A226 WeakPolarHBondContact O-CB 3.44Å; A222-A226 PolarHBondContact O-N 2.63Å
223	A	84	Confident	87.1	Confident	19 Å²	19	65.2 Å²	65.2	16%	0.157	34%	0.337	C	S	.	.	H	α-helix	trans	-63.4	-42.2	175	0	0	0	0	0	111.8	L206 L209 K219 L220 A226 G227	L206-A223 HydrophobicContact CD2-CB 3.79Å; L209-A223 HydrophobicContact CD1-CB 4.17Å; K219-A223 WeakPolarHBondContact O-CB 3.47Å; K219-A223 PolarHBondContact O-N 3.17Å; L220-A223 PolarHBondContact O-N 2.81Å; A223-A226 PolarHBondContact O-N 3.33Å; A223-G227 PolarHBondContact O-N 3.47Å
224	W	82.9	Confident	87.7	Confident	156 Å²	156	65.2 Å²	65.2	59%	0.591	32%	0.315	S	S	*	.	H	α-helix	trans	-63.4	-44.5	177.3	-179.5	-135.7	0	0	0	112	L220 R221 A226 G227 G228 L231	L220-W224 WeakPolarHBondContact O-CB 3.18Å; L220-W224 PolarHBondContact O-N 3.28Å; R221-W224 PolarHBondContact O-N 3.31Å; W224-A226 VanDerWaalsContact C-N 3.29Å; W224-A226 PolarHBondContact O-N 3.15Å; W224-G227 PolarHBondContact O-N 3.16Å; W224-G228 PolarHBondContact O-N 3.18Å; W224-L231 HydrophobicContact CH2-CD2 3.85Å; W224-L231 HydrophobicContact CZ3-CD2 4.24Å
225	V	77.5	Confident	88.3	Confident	32 Å²	32	66.9 Å²	66.9	19%	0.194	32%	0.324	C	S	.	.	H	α-helix	trans	-65.1	-32.1	178.5	168.1	0	0	0	0	112.3	R104 R221 A222	R104-V225 PolarHBondContact NH1-O 2.85Å; R221-V225 WeakPolarHBondContact O-CB 3.48Å; R221-V225 WeakPolarHBondContact O-CG2 3.41Å; R221-V225 PolarHBondContact O-N 3.26Å; A222-V225 PolarHBondContact O-N 3.01Å
226	A	77.7	Confident	88.7	Confident	5 Å²	5	63.9 Å²	63.9	4%	0.041	30%	0.303	C	S	.	.	H	α-helix	trans	-77.2	-41.7	172.7	0	0	0	0	0	112.4	Y202 C205 A222 A223 W224	Y202-A226 HydrophobicContact CD2-CB 3.97Å; C205-A226 HydrophobicContact CB-CB 4.21Å; A222-A226 WeakPolarHBondContact O-CB 3.44Å; A222-A226 PolarHBondContact O-N 2.63Å; A223-A226 PolarHBondContact O-N 3.33Å; W224-A226 VanDerWaalsContact C-N 3.29Å; W224-A226 PolarHBondContact O-N 3.15Å
227	G	89.3	Confident	89.2	Confident	12 Å²	12	57 Å²	57	12%	0.124	27%	0.271	C	S	.	.	H	α-helix	trans	-70.4	-29.8	179.9	0	0	0	0	0	113.5	A223 W224 A229 L230 L231	A223-G227 PolarHBondContact O-N 3.47Å; W224-G227 PolarHBondContact O-N 3.16Å; G227-A229 VanDerWaalsContact C-N 3.33Å; G227-A229 PolarHBondContact O-N 3.17Å; G227-L230 PolarHBondContact O-N 3.06Å; G227-L231 WeakPolarHBondContact O-CB 3.21Å; G227-L231 PolarHBondContact O-N 2.98Å
228	G	92.1	Very high	89.8	Confident	0 Å²	0	49.1 Å²	49.1	0%	0	24%	0.24	C	C	.	.	H	α-helix	trans	-63.6	-34.6	179.9	0	0	0	0	0	113.7	W224 L231 T232	W224-G228 PolarHBondContact O-N 3.18Å; G228-L231 PolarHBondContact O-N 2.92Å; G228-T232 PolarHBondContact O-N 3.3Å; G228-T232 PolarHBondContact O-OG1 2.94Å
229	A	92.9	Very high	90.4	Very high	1 Å²	1	43.8 Å²	43.8	1%	0.008	23%	0.226	C	C	.	.	H	α-helix	trans	-64.3	-46.9	173.3	0	0	0	0	0	111.3	L97 T198 G227 L231 T232 L233	L97-A229 HydrophobicContact CB-CB 4.36Å; L97-A229 HydrophobicContact CD2-CB 3.93Å; T198-A229 HydrophobicContact CG2-CB 4.08Å; G227-A229 VanDerWaalsContact C-N 3.33Å; G227-A229 PolarHBondContact O-N 3.17Å; A229-L231 VanDerWaalsContact C-N 3.35Å; A229-L231 PolarHBondContact O-N 3.36Å; A229-T232 PolarHBondContact O-N 3.22Å; A229-L233 WeakPolarHBondContact O-CG 3.38Å; A229-L233 PolarHBondContact O-N 2.84Å
230	L	96	Very high	90.9	Very high	28 Å²	28	41.6 Å²	41.6	15%	0.147	22%	0.217	C	C	.	.	H	α-helix	trans	-61.9	-43.7	176.6	-175.3	60	0	0	0	111.4	L195 T198 A199 Y202 G227 T232 L233 L234	L195-L230 HydrophobicContact CD1-CD1 3.62Å; T198-L230 HydrophobicContact CG2-CB 4.01Å; T198-L230 HydrophobicContact CG2-CD1 4.31Å; A199-L230 HydrophobicContact CB-CD1 4.17Å; Y202-L230 HydrophobicContact CD1-CD2 3.92Å; Y202-L230 HydrophobicContact CG-CD2 4.22Å; G227-L230 PolarHBondContact O-N 3.06Å; L230-T232 VanDerWaalsContact C-N 3.31Å; L230-T232 PolarHBondContact O-N 3.24Å; L230-L233 PolarHBondContact O-N 2.8Å; L230-L234 HydrophobicContact CD1-CD1 4.23Å; L230-L234 HydrophobicContact CD1-CG 4.39Å; L230-L234 HydrophobicContact CG-CD1 3.98Å; L230-L234 WeakPolarHBondContact O-CB 3.28Å; L230-L234 VanDerWaalsContact O-CG 3.3Å; L230-L234 WeakPolarHBondContact O-CG 3.14Å; L230-L234 PolarHBondContact O-N 3.01Å
231	L	95.8	Very high	91.5	Very high	62 Å²	62	36.3 Å²	36.3	33%	0.325	19%	0.189	S	C	.	.	H	α-helix	trans	-58.2	-43.9	176.3	-175.8	66.7	0	0	0	111.4	W224 G227 G228 A229 L234 L235	W224-L231 HydrophobicContact CH2-CD2 3.85Å; W224-L231 HydrophobicContact CZ3-CD2 4.24Å; G227-L231 WeakPolarHBondContact O-CB 3.21Å; G227-L231 PolarHBondContact O-N 2.98Å; G228-L231 PolarHBondContact O-N 2.92Å; A229-L231 VanDerWaalsContact C-N 3.35Å; A229-L231 PolarHBondContact O-N 3.36Å; L231-L234 PolarHBondContact O-N 2.93Å; L231-L235 HydrophobicContact CD1-CD1 3.54Å; L231-L235 HydrophobicContact CD1-CG 3.84Å; L231-L235 HydrophobicContact CD2-CD1 4.43Å; L231-L235 HydrophobicContact CG-CD1 3.78Å; L231-L235 HydrophobicContact CG-CG 4.25Å; L231-L235 WeakPolarHBondContact O-CB 3.36Å; L231-L235 WeakPolarHBondContact O-CG 3.16Å; L231-L235 PolarHBondContact O-N 2.85Å
232	T	95.9	Very high	92.2	Very high	0 Å²	0	32 Å²	32	0%	0	18%	0.184	C	C	.	.	H	α-helix	trans	-67	-41.7	180	-51	0	0	0	0	112	L97 G228 A229 L230 L234 C236 L271 N272	L97-T232 HydrophobicContact CD1-CG2 4.46Å; G228-T232 PolarHBondContact O-N 3.3Å; G228-T232 PolarHBondContact O-OG1 2.94Å; A229-T232 PolarHBondContact O-N 3.22Å; L230-T232 VanDerWaalsContact C-N 3.31Å; L230-T232 PolarHBondContact O-N 3.24Å; T232-L234 VanDerWaalsContact C-N 3.32Å; T232-L234 PolarHBondContact O-N 3.42Å; T232-C236 HydrophobicContact CG2-CB 4.29Å; T232-C236 VanDerWaalsContact O-CB 3.27Å; T232-C236 WeakPolarHBondContact O-CB 3.39Å; T232-C236 PolarHBondContact O-N 3.31Å; T232-L271 HydrophobicContact CG2-CB 4.04Å; T232-L271 HydrophobicContact CG2-CD2 3.94Å; T232-L271 HydrophobicContact CG2-CG 4.11Å; T232-L271 WeakPolarHBondContact OG1-CD2 3.47Å; T232-L271 WeakPolarHBondContact OG1-CG 3.16Å; T232-N272 WeakPolarHBondContact CG2-OD1 3.41Å
233	L	97.3	Very high	92.9	Very high	0 Å²	0	30.4 Å²	30.4	0%	0	17%	0.17	C	C	.	.	I	π-helix	trans	-59.8	-43.6	173.8	-70	177.1	0	0	0	111.4	L97 F191 L195 T198 A229 L230 L237 G238	L97-L233 HydrophobicContact CD1-CD2 4.07Å; L97-L233 HydrophobicContact CD1-CG 4.18Å; F191-L233 HydrophobicContact CE2-CB 4.34Å; F191-L233 WeakPolarHBondContact CE2-O 3.37Å; L195-L233 HydrophobicContact CD1-CB 3.97Å; L195-L233 HydrophobicContact CD1-CD1 4.23Å; T198-L233 HydrophobicContact CG2-CD1 4Å; T198-L233 WeakPolarHBondContact OG1-CD1 3.17Å; A229-L233 WeakPolarHBondContact O-CG 3.38Å; A229-L233 PolarHBondContact O-N 2.84Å; L230-L233 PolarHBondContact O-N 2.8Å; L233-L237 HydrophobicContact CD2-CD2 4.06Å; L233-L237 CarbonylContact O-C 3.14Å; L233-L237 PolarHBondContact O-N 2.85Å; L233-G238 WeakPolarHBondContact O-CA 3.44Å; L233-G238 PolarHBondContact O-N 3.08Å
234	L	97.9	Very high	93.4	Very high	91 Å²	91	29.6 Å²	29.6	48%	0.476	16%	0.163	S	C	.	.	I	π-helix	trans	-72.7	-40.6	-177.6	-69.7	172.3	0	0	0	113.4	L195 L230 L231 T232 P239	L195-L234 HydrophobicContact CD1-CD2 3.95Å; L195-L234 HydrophobicContact CD1-CG 4.27Å; L195-L234 HydrophobicContact CD2-CD2 4.39Å; L230-L234 HydrophobicContact CD1-CD1 4.23Å; L230-L234 HydrophobicContact CD1-CG 4.39Å; L230-L234 HydrophobicContact CG-CD1 3.98Å; L230-L234 WeakPolarHBondContact O-CB 3.28Å; L230-L234 VanDerWaalsContact O-CG 3.3Å; L230-L234 WeakPolarHBondContact O-CG 3.14Å; L230-L234 PolarHBondContact O-N 3.01Å; L231-L234 PolarHBondContact O-N 2.93Å; T232-L234 VanDerWaalsContact C-N 3.32Å; T232-L234 PolarHBondContact O-N 3.42Å; L234-P239 WeakPolarHBondContact O-CD 3.16Å
235	L	97.2	Very high	94.1	Very high	97 Å²	97	23.9 Å²	23.9	51%	0.508	15%	0.145	S	C	.	.	I	π-helix	trans	-85.6	-37.3	-175.4	-66.5	-174.7	0	0	0	113.4	L231 P239	L231-L235 HydrophobicContact CD1-CD1 3.54Å; L231-L235 HydrophobicContact CD1-CG 3.84Å; L231-L235 HydrophobicContact CD2-CD1 4.43Å; L231-L235 HydrophobicContact CG-CD1 3.78Å; L231-L235 HydrophobicContact CG-CG 4.25Å; L231-L235 WeakPolarHBondContact O-CB 3.36Å; L231-L235 WeakPolarHBondContact O-CG 3.16Å; L231-L235 PolarHBondContact O-N 2.85Å; L235-P239 WeakPolarHBondContact O-CD 3.44Å; L235-P239 WeakPolarHBondContact O-CG 3.34Å
236	C	97.7	Very high	94.9	Very high	8 Å²	8	24.1 Å²	24.1	5%	0.054	15%	0.151	C	C	.	.	I	π-helix	trans	-94.4	-60.3	-174.3	-62	0	0	0	0	111.4	T232 T264 G265	T232-C236 HydrophobicContact CG2-CB 4.29Å; T232-C236 VanDerWaalsContact O-CB 3.27Å; T232-C236 WeakPolarHBondContact O-CB 3.39Å; T232-C236 PolarHBondContact O-N 3.31Å; C236-T264 WeakPolarHBondContact CA-O 3.35Å; C236-T264 WeakPolarHBondContact CB-O 3.29Å; C236-T264 CarbonylContact O-C 3.46Å; C236-T264 WeakPolarHBondContact O-CB 3.39Å; C236-T264 PolarHBondContact O-OG1 2.89Å; C236-G265 VanDerWaalsContact O-CA 3.28Å; C236-G265 WeakPolarHBondContact O-CA 3.3Å; C236-G265 PolarHBondContact O-N 3.28Å
237	L	97.5	Very high	95.6	Very high	2 Å²	2	24.6 Å²	24.6	1%	0.01	15%	0.154	C	C	.	.	I	π-helix	trans	-83.2	-26.8	-175.1	-78	67.3	0	0	0	112.3	L90 F191 L233 Y240 N241	L90-L237 HydrophobicContact CD1-CD1 3.99Å; L90-L237 HydrophobicContact CD1-CG 4.04Å; L90-L237 HydrophobicContact CG-CG 4.44Å; F191-L237 HydrophobicContact CD2-CB 3.75Å; F191-L237 HydrophobicContact CD2-CD2 4.36Å; F191-L237 HydrophobicContact CE2-CB 3.67Å; L233-L237 HydrophobicContact CD2-CD2 4.06Å; L233-L237 CarbonylContact O-C 3.14Å; L233-L237 PolarHBondContact O-N 2.85Å; L237-Y240 PolarHBondContact O-N 2.72Å; L237-N241 PolarHBondContact O-N 3.06Å; L237-N241 PolarHBondContact O-ND2 2.6Å
238	G	97.8	Very high	95.8	Very high	12 Å²	12	28.4 Å²	28.4	12%	0.124	17%	0.167	C	C	.	.	H	α-helix	trans	-56.3	-53.6	-177.2	0	0	0	0	0	113.3	F191 L233 Y240 N241 A242	F191-G238 VanDerWaalsContact CZ-CA 3.5Å; L233-G238 WeakPolarHBondContact O-CA 3.44Å; L233-G238 PolarHBondContact O-N 3.08Å; G238-Y240 VanDerWaalsContact C-N 3.3Å; G238-Y240 PolarHBondContact O-N 2.77Å; G238-N241 PolarHBondContact O-N 3.31Å; G238-A242 WeakPolarHBondContact O-CB 3.45Å; G238-A242 PolarHBondContact O-N 2.97Å
239	P	97.1	Very high	95.9	Very high	47 Å²	47	34.6 Å²	34.6	31%	0.305	20%	0.199	S	C	.	.	H	α-helix	trans	-61.2	-38.2	-178.7	-24.3	35.3	0	0	0	112.6	L234 L235 S243 T264	L234-P239 WeakPolarHBondContact O-CD 3.16Å; L235-P239 WeakPolarHBondContact O-CD 3.44Å; L235-P239 WeakPolarHBondContact O-CG 3.34Å; P239-S243 WeakPolarHBondContact O-CB 3.44Å; P239-S243 PolarHBondContact O-N 3.49Å; P239-T264 HydrophobicContact CB-CG2 4.41Å; P239-T264 WeakPolarHBondContact CB-OG1 3.31Å; P239-T264 HydrophobicContact CG-CG2 4.21Å
240	Y	96.2	Very high	96	Very high	7 Å²	7	38 Å²	38	3%	0.027	22%	0.217	C	C	.	.	H	α-helix	trans	-62.7	-51.9	175.6	-177.8	-119.6	0	0	0	112.3	F87 L90 Y91 L237 G238 S243 N244 R258 G261 L262	F87-Y240 HydrophobicContact CD1-CE1 4.38Å; F87-Y240 HydrophobicContact CE1-CE1 4.19Å; F87-Y240 HydrophobicContact CE1-CE2 4.42Å; F87-Y240 AromaticContact CE1-CZ 3.72Å; F87-Y240 WeakPolarHBondContact CE1-OH 3.39Å; L90-Y240 HydrophobicContact CD2-CD1 4.32Å; L90-Y240 HydrophobicContact CD2-CE1 4.48Å; Y91-Y240 HydrophobicContact CE2-CE1 4.23Å; Y91-Y240 WeakPolarHBondContact OH-CE1 3.39Å; L237-Y240 PolarHBondContact O-N 2.72Å; G238-Y240 VanDerWaalsContact C-N 3.3Å; G238-Y240 PolarHBondContact O-N 2.77Å; Y240-S243 WeakPolarHBondContact O-CB 3.35Å; Y240-S243 PolarHBondContact O-N 3.46Å; Y240-S243 PolarHBondContact O-OG 2.74Å; Y240-N244 PolarHBondContact O-N 2.87Å; Y240-N244 VanDerWaalsContact O-N 3.1Å; Y240-R258 HydrophobicContact CE2-CG 4.25Å; Y240-G261 WeakPolarHBondContact CB-O 3.47Å; Y240-L262 HydrophobicContact CD2-CD2 3.8Å; Y240-L262 HydrophobicContact CD2-CG 3.94Å; Y240-L262 HydrophobicContact CE2-CD2 3.31Å; Y240-L262 HydrophobicContact CE2-CG 3.74Å
241	N	97.5	Very high	95.6	Very high	0 Å²	0	39.6 Å²	39.6	0%	0	23%	0.229	C	C	.	.	H	α-helix	trans	-71.8	-32.9	-177.1	-71.2	-77.2	0	0	0	112.4	Y91 S187 F191 L237 G238 S243 N244 V245	Y91-N241 VanDerWaalsContact CE1-OD1 3.3Å; Y91-N241 WeakPolarHBondContact CE1-OD1 3.3Å; Y91-N241 PolarHBondContact OH-OD1 2.73Å; S187-N241 WeakPolarHBondContact CA-OD1 3.43Å; S187-N241 WeakPolarHBondContact CB-OD1 3.3Å; S187-N241 PolarHBondContact OG-OD1 3.08Å; F191-N241 HydrophobicContact CB-CB 4.03Å; F191-N241 WeakPolarHBondContact CB-OD1 3.32Å; F191-N241 HydrophobicContact CD1-CB 3.34Å; F191-N241 HydrophobicContact CD2-CB 4.31Å; F191-N241 WeakPolarHBondContact CD2-ND2 3.23Å; F191-N241 HydrophobicContact CE1-CB 3.83Å; F191-N241 HydrophobicContact CG-CB 3.62Å; F191-N241 WeakPolarHBondContact CG-ND2 3.25Å; L237-N241 PolarHBondContact O-N 3.06Å; L237-N241 PolarHBondContact O-ND2 2.6Å; G238-N241 PolarHBondContact O-N 3.31Å; N241-S243 VanDerWaalsContact C-N 3.32Å; N241-N244 PolarHBondContact O-N 2.98Å; N241-V245 WeakPolarHBondContact O-CG2 3.07Å; N241-V245 PolarHBondContact O-N 3.17Å; N241-V245 VanDerWaalsContact O-N 3.15Å
242	A	96	Very high	95.2	Very high	53 Å²	53	43.8 Å²	43.8	44%	0.438	25%	0.252	S	S	.	.	H	α-helix	trans	-63.3	-39.9	170	0	0	0	0	0	111.3	G238 N244 V245 A246	G238-A242 WeakPolarHBondContact O-CB 3.45Å; G238-A242 PolarHBondContact O-N 2.97Å; A242-N244 VanDerWaalsContact C-N 3.32Å; A242-N244 PolarHBondContact O-N 2.97Å; A242-V245 PolarHBondContact O-N 3.42Å; A242-A246 VanDerWaalsContact O-CB 3.3Å; A242-A246 WeakPolarHBondContact O-CB 3.28Å; A242-A246 PolarHBondContact O-N 3.22Å
243	S	95.1	Very high	94.6	Very high	6 Å²	6	46.5 Å²	46.5	4%	0.042	27%	0.266	C	S	.	.	H	α-helix	trans	-62.7	-38	175.2	80	0	0	0	0	112.3	P239 Y240 N241 A246 S247 R258	P239-S243 WeakPolarHBondContact O-CB 3.44Å; P239-S243 PolarHBondContact O-N 3.49Å; Y240-S243 WeakPolarHBondContact O-CB 3.35Å; Y240-S243 PolarHBondContact O-N 3.46Å; Y240-S243 PolarHBondContact O-OG 2.74Å; N241-S243 VanDerWaalsContact C-N 3.32Å; S243-A246 PolarHBondContact O-N 3.29Å; S243-S247 WeakPolarHBondContact O-CB 3.18Å; S243-S247 PolarHBondContact O-N 3.36Å; S243-S247 PolarHBondContact O-OG 3.18Å; S243-S247 VanDerWaalsContact O-OG 3.13Å; S243-R258 WeakPolarHBondContact OG-CA 3.48Å
244	N	95.1	Very high	93.7	Very high	3 Å²	3	48.8 Å²	48.8	2%	0.016	29%	0.29	C	S	.	.	H	α-helix	trans	-64.1	-43.3	176.2	-67.6	-23.4	0	0	0	111.9	R183 S187 Y240 N241 A242 F248	R183-N244 HydrophobicContact CB-CB 4.09Å; S187-N244 WeakPolarHBondContact OG-CB 3.04Å; S187-N244 PolarHBondContact OG-ND2 3.19Å; S187-N244 VanDerWaalsContact OG-ND2 3.1Å; Y240-N244 PolarHBondContact O-N 2.87Å; Y240-N244 VanDerWaalsContact O-N 3.1Å; N241-N244 PolarHBondContact O-N 2.98Å; A242-N244 VanDerWaalsContact C-N 3.32Å; A242-N244 PolarHBondContact O-N 2.97Å; N244-F248 PolarHBondContact O-N 3.3Å; N244-F248 VanDerWaalsContact O-N 3.13Å
245	V	95.8	Very high	92.8	Very high	35 Å²	35	49.2 Å²	49.2	21%	0.212	29%	0.292	C	S	.	.	H	α-helix	trans	-64.3	-46.1	175.3	174.8	0	0	0	0	110.6	L184 F192 N241 A242 S247 F248 I249	L184-V245 HydrophobicContact CD1-CG2 3.88Å; F192-V245 HydrophobicContact CE2-CG2 3.62Å; F192-V245 HydrophobicContact CZ-CG2 3.94Å; N241-V245 WeakPolarHBondContact O-CG2 3.07Å; N241-V245 PolarHBondContact O-N 3.17Å; N241-V245 VanDerWaalsContact O-N 3.15Å; A242-V245 PolarHBondContact O-N 3.42Å; V245-S247 PolarHBondContact O-N 3.26Å; V245-F248 WeakPolarHBondContact O-CB 3.46Å; V245-F248 PolarHBondContact O-N 2.88Å; V245-F248 VanDerWaalsContact O-N 3.15Å; V245-I249 HydrophobicContact CG1-CD1 3.69Å; V245-I249 HydrophobicContact CG1-CG1 4.41Å; V245-I249 WeakPolarHBondContact O-CG1 3.44Å; V245-I249 PolarHBondContact O-N 2.86Å
246	A	94.6	Very high	92.3	Very high	38 Å²	38	46.7 Å²	46.7	31%	0.314	28%	0.283	S	S	.	.	H	α-helix	trans	-61	-46.3	-179.6	0	0	0	0	0	111.4	A242 S243 F248 I249 N250 L253	A242-A246 VanDerWaalsContact O-CB 3.3Å; A242-A246 WeakPolarHBondContact O-CB 3.28Å; A242-A246 PolarHBondContact O-N 3.22Å; S243-A246 PolarHBondContact O-N 3.29Å; A246-F248 VanDerWaalsContact C-N 3.25Å; A246-F248 PolarHBondContact O-N 2.9Å; A246-I249 PolarHBondContact O-N 3.44Å; A246-N250 PolarHBondContact O-N 3.46Å; A246-L253 HydrophobicContact CB-CD1 3.78Å
247	S	92.7	Very high	91.8	Very high	15 Å²	15	54.8 Å²	54.8	11%	0.105	31%	0.312	C	S	.	.	H	α-helix	trans	-66.5	-23.2	176.6	-65.8	0	0	0	0	114	R180 S243 V245	R180-S247 VanDerWaalsContact CD-O 3.31Å; R180-S247 WeakPolarHBondContact CD-O 3.48Å; R180-S247 PolarHBondContact NE-O 3.45Å; S243-S247 WeakPolarHBondContact O-CB 3.18Å; S243-S247 PolarHBondContact O-N 3.36Å; S243-S247 PolarHBondContact O-OG 3.18Å; S243-S247 VanDerWaalsContact O-OG 3.13Å; V245-S247 PolarHBondContact O-N 3.26Å
248	F	94.2	Very high	91.5	Very high	92 Å²	92	54.8 Å²	54.8	40%	0.404	31%	0.312	S	S	.	.	H	α-helix	trans	-76.6	-43.1	172.5	-178.6	-90.2	0	0	0	111.7	R180 P181 L184 N244 V245 A246	R180-F248 HydrophobicContact CB-CD2 4.12Å; P181-F248 HydrophobicContact CB-CE2 4.42Å; P181-F248 HydrophobicContact CG-CE2 4.19Å; L184-F248 HydrophobicContact CB-CD2 4.18Å; L184-F248 HydrophobicContact CB-CG 4.37Å; L184-F248 HydrophobicContact CD2-CB 4.49Å; L184-F248 HydrophobicContact CD2-CD1 3.64Å; L184-F248 HydrophobicContact CD2-CD2 3.77Å; L184-F248 HydrophobicContact CD2-CE1 3.65Å; L184-F248 HydrophobicContact CD2-CE2 3.79Å; L184-F248 HydrophobicContact CD2-CG 3.7Å; L184-F248 HydrophobicContact CD2-CZ 3.73Å; L184-F248 HydrophobicContact CG-CG 4.48Å; N244-F248 PolarHBondContact O-N 3.3Å; N244-F248 VanDerWaalsContact O-N 3.13Å; V245-F248 WeakPolarHBondContact O-CB 3.46Å; V245-F248 PolarHBondContact O-N 2.88Å; V245-F248 VanDerWaalsContact O-N 3.15Å; A246-F248 VanDerWaalsContact C-N 3.25Å; A246-F248 PolarHBondContact O-N 2.9Å
249	I	94.7	Very high	91.3	Very high	129 Å²	129	59.8 Å²	59.8	66%	0.662	33%	0.331	S	S	*	.	H	α-helix	trans	-74.9	-42.3	-178.4	-64.8	171.8	0	0	0	111.6	V245 A246	V245-I249 HydrophobicContact CG1-CD1 3.69Å; V245-I249 HydrophobicContact CG1-CG1 4.41Å; V245-I249 WeakPolarHBondContact O-CG1 3.44Å; V245-I249 PolarHBondContact O-N 2.86Å; A246-I249 PolarHBondContact O-N 3.44Å
250	N	93.4	Very high	91.1	Very high	73 Å²	73	61 Å²	61	39%	0.39	33%	0.334	S	S	.	.			trans	-124.7	92.7	-179.1	-176.9	-15.1	0	0	0	109.4	A246 D252 L253	A246-N250 PolarHBondContact O-N 3.46Å; N250-D252 PolarHBondContact O-N 3.32Å; N250-D252 PolarHBondContact OD1-N 2.88Å; N250-L253 HydrophobicContact CB-CD1 3.74Å; N250-L253 HydrophobicContact CB-CG 4.13Å; N250-L253 WeakPolarHBondContact O-CB 3.49Å; N250-L253 PolarHBondContact O-N 3.13Å
251	P	87.7	Confident	91	Very high	61 Å²	61	60.7 Å²	60.7	40%	0.396	33%	0.333	S	S	.	.	T	Hydrogen-bonded Turn	trans	-57.9	-23.9	-179.6	-30.8	39.3	0	0	0	115.7	R180 L253	R180-P251 PolarHBondContact NH2-O 3.37Å; R180-P251 VanDerWaalsContact NH2-O 3.16Å; P251-L253 VanDerWaalsContact C-N 3.28Å; P251-L253 PolarHBondContact O-N 3.37Å
252	D	87.3	Confident	91	Very high	150 Å²	150	61 Å²	61	80%	0.802	33%	0.334	S	S	*	.	T	Hydrogen-bonded Turn	trans	-83.4	-5.8	-175.3	-57.5	-38	0	0	0	112.5	N250 G254	N250-D252 PolarHBondContact O-N 3.32Å; N250-D252 PolarHBondContact OD1-N 2.88Å; D252-G254 PolarHBondContact O-N 2.93Å
253	L	84.5	Confident	91	Very high	58 Å²	58	58.9 Å²	58.9	30%	0.304	32%	0.316	S	S	.	.	S	Bend	trans	-65.3	114.4	171	-79.5	163.9	0	0	0	110.3	A246 N250 P251	A246-L253 HydrophobicContact CB-CD1 3.78Å; N250-L253 HydrophobicContact CB-CD1 3.74Å; N250-L253 HydrophobicContact CB-CG 4.13Å; N250-L253 WeakPolarHBondContact O-CB 3.49Å; N250-L253 PolarHBondContact O-N 3.13Å; P251-L253 VanDerWaalsContact C-N 3.28Å; P251-L253 PolarHBondContact O-N 3.37Å
254	G	77.2	Confident	91.2	Very high	48 Å²	48	60.1 Å²	60.1	50%	0.495	32%	0.323	S	S	.	.			trans	-62.3	160.3	176.1	0	0	0	0	0	114.2	D252 S256	D252-G254 PolarHBondContact O-N 2.93Å; G254-S256 PolarHBondContact O-N 3.18Å
255	D	80.3	Confident	91.3	Very high	99 Å²	99	60 Å²	60	53%	0.529	32%	0.323	S	S	.	.	T	Hydrogen-bonded Turn	trans	-69.7	-3	-169.4	-63.5	-41	0	0	0	116.2	W257 R258 K259	D255-W257 VanDerWaalsContact C-N 3.3Å; D255-W257 PolarHBondContact O-N 3.16Å; D255-R258 PolarHBondContact O-N 3.36Å; D255-K259 PolarHBondContact O-N 3.24Å; D255-K259 VanDerWaalsContact O-N 3.1Å
256	S	85.9	Confident	91.4	Very high	45 Å²	45	58.4 Å²	58.4	32%	0.315	31%	0.313	S	S	.	.	H	α-helix	trans	-60.6	-38.8	-175.1	-64.9	0	0	0	0	112.5	G254 R258 K259 L260	G254-S256 PolarHBondContact O-N 3.18Å; S256-R258 VanDerWaalsContact C-N 3.34Å; S256-R258 PolarHBondContact O-N 2.82Å; S256-K259 PolarHBondContact O-N 3.02Å; S256-L260 PolarHBondContact O-N 2.95Å; S256-L260 VanDerWaalsContact O-N 3.1Å
257	W	87.7	Confident	91.6	Very high	177 Å²	177	60.5 Å²	60.5	67%	0.67	31%	0.313	S	S	*	.	H	α-helix	trans	-65.7	-38.1	178.6	-64.9	95.9	0	0	0	112.2	D255 L260 G261	D255-W257 VanDerWaalsContact C-N 3.3Å; D255-W257 PolarHBondContact O-N 3.16Å; W257-L260 PolarHBondContact O-N 3.3Å; W257-G261 PolarHBondContact O-N 2.85Å
258	R	91.4	Very high	91.9	Very high	3 Å²	3	59.8 Å²	59.8	1%	0.011	31%	0.308	C	S	.	.	H	α-helix	trans	-68.1	-43.2	178.2	-163.3	178.9	98.9	92.9	-3.4	111.6	E172 Y240 S243 D255 S256 L260 G261 L262	E172-R258 IonicContact OE1-CZ 3.71Å; E172-R258 IonicContact OE1-NH2 2.73Å; E172-R258 PolarHBondContact OE1-NH2 3.28Å; E172-R258 IonicContact OE2-CZ 3.54Å; E172-R258 IonicContact OE2-NE 3.87Å; E172-R258 IonicContact OE2-NH2 2.6Å; E172-R258 PolarHBondContact OE2-NH2 2.81Å; Y240-R258 HydrophobicContact CE2-CG 4.25Å; S243-R258 WeakPolarHBondContact OG-CA 3.48Å; D255-R258 PolarHBondContact O-N 3.36Å; S256-R258 VanDerWaalsContact C-N 3.34Å; S256-R258 PolarHBondContact O-N 2.82Å; R258-L260 VanDerWaalsContact C-N 3.33Å; R258-L260 PolarHBondContact O-N 2.97Å; R258-G261 PolarHBondContact O-N 3.24Å; R258-L262 WeakPolarHBondContact O-CG 3.44Å; R258-L262 PolarHBondContact O-N 3.36Å
259	K	91.9	Very high	92.1	Very high	116 Å²	116	55.4 Å²	55.4	50%	0.504	29%	0.289	S	S	.	.	H	α-helix	trans	-59.4	-43.9	175.1	-69.9	-178.1	-179.1	-177.9	0	111.7	D255 S256 L262 I263	D255-K259 PolarHBondContact O-N 3.24Å; D255-K259 VanDerWaalsContact O-N 3.1Å; S256-K259 PolarHBondContact O-N 3.02Å; K259-L262 PolarHBondContact O-N 3.23Å; K259-I263 WeakPolarHBondContact O-CG1 3.45Å; K259-I263 PolarHBondContact O-N 3.35Å
260	L	93.3	Very high	92.2	Very high	74 Å²	74	50 Å²	50	39%	0.387	26%	0.262	S	S	.	.	H	α-helix	trans	-62.4	-44.6	174.4	-177.8	62.9	0	0	0	111.4	L3 S256 W257 R258 L262 I263 T264	L3-L260 HydrophobicContact CD1-CB 4.44Å; L3-L260 HydrophobicContact CD1-CD1 4.23Å; S256-L260 PolarHBondContact O-N 2.95Å; S256-L260 VanDerWaalsContact O-N 3.1Å; W257-L260 PolarHBondContact O-N 3.3Å; R258-L260 VanDerWaalsContact C-N 3.33Å; R258-L260 PolarHBondContact O-N 2.97Å; L260-L262 PolarHBondContact O-N 3.47Å; L260-I263 WeakPolarHBondContact O-CB 3.49Å; L260-I263 PolarHBondContact O-N 2.85Å; L260-T264 PolarHBondContact O-N 3.11Å
261	G	95.5	Very high	92.4	Very high	0 Å²	0	48.4 Å²	48.4	0%	0	25%	0.253	C	S	.	.	H	α-helix	trans	-60.5	-40.3	177	0	0	0	0	0	113.8	Y240 W257 R258 I263 T264 G265	Y240-G261 WeakPolarHBondContact CB-O 3.47Å; W257-G261 PolarHBondContact O-N 2.85Å; R258-G261 PolarHBondContact O-N 3.24Å; G261-I263 VanDerWaalsContact C-N 3.3Å; G261-I263 PolarHBondContact O-N 2.89Å; G261-T264 WeakPolarHBondContact CA-OG1 3.43Å; G261-T264 PolarHBondContact O-N 3Å; G261-T264 PolarHBondContact O-OG1 3.35Å; G261-G265 PolarHBondContact O-N 3.49Å
262	L	96.1	Very high	92.8	Very high	5 Å²	5	45.5 Å²	45.5	3%	0.026	23%	0.234	C	C	.	.	H	α-helix	trans	-58.9	-43.2	174.2	-74	169.2	0	0	0	111.5	Y12 F87 Y240 R258 K259 L260 G265 A266	Y12-L262 WeakPolarHBondContact OH-CB 3.42Å; F87-L262 HydrophobicContact CE1-CD2 3.52Å; F87-L262 HydrophobicContact CZ-CD2 3.68Å; Y240-L262 HydrophobicContact CD2-CD2 3.8Å; Y240-L262 HydrophobicContact CD2-CG 3.94Å; Y240-L262 HydrophobicContact CE2-CD2 3.31Å; Y240-L262 HydrophobicContact CE2-CG 3.74Å; R258-L262 WeakPolarHBondContact O-CG 3.44Å; R258-L262 PolarHBondContact O-N 3.36Å; K259-L262 PolarHBondContact O-N 3.23Å; L260-L262 PolarHBondContact O-N 3.47Å; L262-G265 PolarHBondContact O-N 3.1Å; L262-A266 PolarHBondContact O-N 3.18Å
263	I	97.2	Very high	93	Very high	10 Å²	10	38.4 Å²	38.4	5%	0.051	20%	0.196	C	C	.	.	H	α-helix	trans	-63.8	-49.1	176.6	-65.2	167.7	0	0	0	110.2	L3 L11 Y12 K259 L260 G261 G265 A266 W267	L3-I263 HydrophobicContact CD2-CD1 3.96Å; L11-I263 HydrophobicContact CB-CG2 3.91Å; L11-I263 HydrophobicContact CD1-CD1 4.22Å; L11-I263 HydrophobicContact CD1-CG2 4.01Å; L11-I263 HydrophobicContact CG-CG2 4.49Å; Y12-I263 HydrophobicContact CE1-CG1 4.32Å; Y12-I263 HydrophobicContact CE2-CG1 3.9Å; K259-I263 WeakPolarHBondContact O-CG1 3.45Å; K259-I263 PolarHBondContact O-N 3.35Å; L260-I263 WeakPolarHBondContact O-CB 3.49Å; L260-I263 PolarHBondContact O-N 2.85Å; G261-I263 VanDerWaalsContact C-N 3.3Å; G261-I263 PolarHBondContact O-N 2.89Å; I263-G265 PolarHBondContact O-N 3.27Å; I263-A266 VanDerWaalsContact O-CB 3.25Å; I263-A266 WeakPolarHBondContact O-CB 3.36Å; I263-A266 PolarHBondContact O-N 3.32Å; I263-A266 VanDerWaalsContact O-N 3.08Å; I263-W267 VanDerWaalsContact O-CD1 3.24Å; I263-W267 PolarHBondContact O-N 2.78Å
264	T	97.9	Very high	93.4	Very high	32 Å²	32	40 Å²	40	20%	0.196	21%	0.205	C	C	.	.	H	α-helix	trans	-60.8	-37.4	178.9	62.6	0	0	0	0	111.6	C236 P239 L260 G261 A266 W267	C236-T264 WeakPolarHBondContact CA-O 3.35Å; C236-T264 WeakPolarHBondContact CB-O 3.29Å; C236-T264 CarbonylContact O-C 3.46Å; C236-T264 WeakPolarHBondContact O-CB 3.39Å; C236-T264 PolarHBondContact O-OG1 2.89Å; P239-T264 HydrophobicContact CB-CG2 4.41Å; P239-T264 WeakPolarHBondContact CB-OG1 3.31Å; P239-T264 HydrophobicContact CG-CG2 4.21Å; L260-T264 PolarHBondContact O-N 3.11Å; G261-T264 WeakPolarHBondContact CA-OG1 3.43Å; G261-T264 PolarHBondContact O-N 3Å; G261-T264 PolarHBondContact O-OG1 3.35Å; T264-A266 VanDerWaalsContact C-N 3.35Å; T264-A266 PolarHBondContact O-N 3.1Å; T264-W267 PolarHBondContact O-N 3.1Å
265	G	98.1	Very high	93.8	Very high	0 Å²	0	38.3 Å²	38.3	0%	0	18%	0.184	C	C	.	.	H	α-helix	trans	-60.2	-44	174.6	0	0	0	0	0	111.8	L90 C236 G261 L262 I263 W267 S268	L90-G265 WeakPolarHBondContact CD1-O 3.46Å; C236-G265 VanDerWaalsContact O-CA 3.28Å; C236-G265 WeakPolarHBondContact O-CA 3.3Å; C236-G265 PolarHBondContact O-N 3.28Å; G261-G265 PolarHBondContact O-N 3.49Å; L262-G265 PolarHBondContact O-N 3.1Å; I263-G265 PolarHBondContact O-N 3.27Å; G265-W267 VanDerWaalsContact C-N 3.27Å; G265-W267 PolarHBondContact O-N 3.02Å; G265-S268 VanDerWaalsContact O-CB 3.23Å; G265-S268 WeakPolarHBondContact O-CB 3.31Å; G265-S268 PolarHBondContact O-N 2.95Å; G265-S268 VanDerWaalsContact O-N 3.08Å; G265-S268 PolarHBondContact O-OG 3.42Å
266	A	98.3	Very high	93.8	Very high	1 Å²	1	33.9 Å²	33.9	1%	0.008	16%	0.161	C	C	.	.	H	α-helix	trans	-56.6	-41	175.8	0	0	0	0	0	112	Y12 L59 L262 I263 T264 S268 V269	Y12-A266 HydrophobicContact CD1-CB 3.79Å; Y12-A266 HydrophobicContact CE1-CB 3.66Å; L59-A266 HydrophobicContact CD1-CB 4.37Å; L59-A266 HydrophobicContact CD2-CB 3.82Å; L262-A266 PolarHBondContact O-N 3.18Å; I263-A266 VanDerWaalsContact O-CB 3.25Å; I263-A266 WeakPolarHBondContact O-CB 3.36Å; I263-A266 PolarHBondContact O-N 3.32Å; I263-A266 VanDerWaalsContact O-N 3.08Å; T264-A266 VanDerWaalsContact C-N 3.35Å; T264-A266 PolarHBondContact O-N 3.1Å; A266-S268 PolarHBondContact O-N 3.45Å; A266-S268 VanDerWaalsContact O-N 3.08Å; A266-V269 VanDerWaalsContact O-CG2 3.3Å; A266-V269 WeakPolarHBondContact O-CG2 3.33Å; A266-V269 PolarHBondContact O-N 3.49Å
267	W	98.5	Very high	93.1	Very high	82 Å²	82	33.2 Å²	33.2	31%	0.311	16%	0.161	S	C	.	.	T	Hydrogen-bonded Turn	trans	-68.3	-6	-179.4	-80.7	70.6	0	0	0	114.4	L11 A15 L18 I263 T264 G265 V269 V270 L271	L11-W267 HydrophobicContact CD2-CZ2 4.13Å; L11-W267 PolarHBondContact O-NE1 2.93Å; A15-W267 HydrophobicContact CB-CD2 4.34Å; A15-W267 HydrophobicContact CB-CG 4.25Å; L18-W267 HydrophobicContact CD1-CH2 4.46Å; L18-W267 HydrophobicContact CD1-CZ3 4.41Å; I263-W267 VanDerWaalsContact O-CD1 3.24Å; I263-W267 PolarHBondContact O-N 2.78Å; T264-W267 PolarHBondContact O-N 3.1Å; G265-W267 VanDerWaalsContact C-N 3.27Å; G265-W267 PolarHBondContact O-N 3.02Å; W267-V269 PolarHBondContact O-N 3.19Å; W267-V270 HydrophobicContact CE3-CB 4.44Å; W267-V270 HydrophobicContact CE3-CG2 4.27Å; W267-V270 PolarHBondContact O-N 3.44Å; W267-L271 PolarHBondContact O-N 2.9Å
268	S	98.1	Very high	92.3	Very high	0 Å²	0	25.7 Å²	25.7	0%	0	13%	0.133	C	C	.	.	H	α-helix	trans	-57.7	-32.7	168.9	63.5	0	0	0	0	112.4	G265 A266 V270 L271 N272	G265-S268 VanDerWaalsContact O-CB 3.23Å; G265-S268 WeakPolarHBondContact O-CB 3.31Å; G265-S268 PolarHBondContact O-N 2.95Å; G265-S268 VanDerWaalsContact O-N 3.08Å; G265-S268 PolarHBondContact O-OG 3.42Å; A266-S268 PolarHBondContact O-N 3.45Å; A266-S268 VanDerWaalsContact O-N 3.08Å; S268-V270 PolarHBondContact O-N 3.5Å; S268-V270 VanDerWaalsContact O-N 3.13Å; S268-L271 PolarHBondContact O-N 2.99Å; S268-N272 VanDerWaalsContact O-CB 3.25Å; S268-N272 WeakPolarHBondContact O-CB 3.17Å; S268-N272 PolarHBondContact O-N 3.19Å; S268-N272 PolarHBondContact O-ND2 2.84Å
269	V	98.4	Very high	91	Very high	0 Å²	0	28 Å²	28	0%	0	15%	0.145	C	C	.	.	H	α-helix	trans	-61.7	-23.4	177	-53.7	0	0	0	0	112.6	A15 N23 D52 L55 A56 L59 A266 W267 P273	A15-V269 WeakPolarHBondContact O-CG2 3.3Å; N23-V269 PolarHBondContact ND2-O 2.9Å; D52-V269 HydrophobicContact CB-CB 4.43Å; D52-V269 HydrophobicContact CB-CG1 4.31Å; D52-V269 WeakPolarHBondContact O-CG1 3.35Å; L55-V269 HydrophobicContact CB-CG1 3.89Å; L55-V269 HydrophobicContact CD2-CG1 3.56Å; L55-V269 HydrophobicContact CG-CG1 3.59Å; A56-V269 HydrophobicContact CB-CB 4.47Å; A56-V269 HydrophobicContact CB-CG1 4.34Å; L59-V269 HydrophobicContact CD1-CG2 3.99Å; A266-V269 VanDerWaalsContact O-CG2 3.3Å; A266-V269 WeakPolarHBondContact O-CG2 3.33Å; A266-V269 PolarHBondContact O-N 3.49Å; W267-V269 PolarHBondContact O-N 3.19Å; V269-P273 VanDerWaalsContact O-CD 3.23Å; V269-P273 WeakPolarHBondContact O-CD 3.34Å; V269-P273 WeakPolarHBondContact O-CG 3.43Å
270	V	98	Very high	89.3	Confident	16 Å²	16	25.7 Å²	25.7	10%	0.097	15%	0.154	C	C	.	.	H	α-helix	trans	-88.2	-44.6	176.5	-178	0	0	0	0	110	L18 L22 W267 S268 P273 L274	L18-V270 HydrophobicContact CB-CG1 4.32Å; L18-V270 HydrophobicContact CB-CG2 3.89Å; L22-V270 HydrophobicContact CD1-CG1 3.88Å; W267-V270 HydrophobicContact CE3-CB 4.44Å; W267-V270 HydrophobicContact CE3-CG2 4.27Å; W267-V270 PolarHBondContact O-N 3.44Å; S268-V270 PolarHBondContact O-N 3.5Å; S268-V270 VanDerWaalsContact O-N 3.13Å; V270-P273 WeakPolarHBondContact O-CD 3.42Å; V270-P273 WeakPolarHBondContact O-CG 3.44Å; V270-L274 HydrophobicContact CG1-CD1 4.29Å; V270-L274 WeakPolarHBondContact O-CD1 3.36Å; V270-L274 WeakPolarHBondContact O-CG 3.38Å
271	L	96.3	Very high	86.8	Confident	39 Å²	39	26.8 Å²	26.8	20%	0.204	17%	0.174	C	C	.	.	H	α-helix	trans	-76.2	-38.7	-172	-166.7	59.3	0	0	0	113	T232 W267 S268 L274 V275	T232-L271 HydrophobicContact CG2-CB 4.04Å; T232-L271 HydrophobicContact CG2-CD2 3.94Å; T232-L271 HydrophobicContact CG2-CG 4.11Å; T232-L271 WeakPolarHBondContact OG1-CD2 3.47Å; T232-L271 WeakPolarHBondContact OG1-CG 3.16Å; W267-L271 PolarHBondContact O-N 2.9Å; S268-L271 PolarHBondContact O-N 2.99Å; L271-L274 WeakPolarHBondContact O-CB 3.25Å; L271-L274 PolarHBondContact O-N 3.2Å; L271-L274 VanDerWaalsContact O-N 3.15Å; L271-V275 HydrophobicContact CD1-CG1 4.19Å; L271-V275 HydrophobicContact CG-CG1 4.21Å; L271-V275 WeakPolarHBondContact O-CG2 3.49Å; L271-V275 PolarHBondContact O-N 3.41Å
272	N	95.8	Very high	84.6	Confident	0 Å²	0	27.5 Å²	27.5	0%	0	18%	0.181	C	C	.	.	H	α-helix	trans	-53.4	-54	179.1	-75.4	-16.6	0	0	0	114	D52 T232 S268 L274 V275 T276	D52-N272 VanDerWaalsContact CG-ND2 3.26Å; D52-N272 PolarHBondContact OD1-ND2 2.69Å; D52-N272 WeakPolarHBondContact OD2-CB 3.17Å; D52-N272 PolarHBondContact OD2-ND2 3.23Å; T232-N272 WeakPolarHBondContact CG2-OD1 3.41Å; S268-N272 VanDerWaalsContact O-CB 3.25Å; S268-N272 WeakPolarHBondContact O-CB 3.17Å; S268-N272 PolarHBondContact O-N 3.19Å; S268-N272 PolarHBondContact O-ND2 2.84Å; N272-L274 PolarHBondContact O-N 2.96Å; N272-V275 VanDerWaalsContact O-CG2 3.31Å; N272-V275 WeakPolarHBondContact O-CG2 3.48Å; N272-V275 PolarHBondContact O-N 3.18Å; N272-T276 WeakPolarHBondContact O-CG2 3.48Å; N272-T276 PolarHBondContact O-N 3.34Å; N272-T276 PolarHBondContact O-OG1 3.29Å
273	P	93.4	Very high	82.4	Confident	2 Å²	2	28.7 Å²	28.7	1%	0.013	19%	0.189	C	C	.	.	H	α-helix	trans	-63.7	-29.6	179.1	23	-33.3	0	0	0	112.8	L22 A26 V269 V270 T276 L279	L22-P273 HydrophobicContact CB-CB 4.15Å; L22-P273 HydrophobicContact CB-CG 3.67Å; L22-P273 HydrophobicContact CD1-CG 4.48Å; A26-P273 HydrophobicContact CB-CB 3.85Å; V269-P273 VanDerWaalsContact O-CD 3.23Å; V269-P273 WeakPolarHBondContact O-CD 3.34Å; V269-P273 WeakPolarHBondContact O-CG 3.43Å; V270-P273 WeakPolarHBondContact O-CD 3.42Å; V270-P273 WeakPolarHBondContact O-CG 3.44Å; P273-T276 PolarHBondContact O-OG1 3.17Å; P273-L279 HydrophobicContact CB-CD2 4.36Å; P273-L279 WeakPolarHBondContact O-CD1 3.28Å
274	L	91.1	Very high	79.8	Confident	92 Å²	92	30.3 Å²	30.3	48%	0.482	21%	0.208	S	C	.	.	H	α-helix	trans	-69.4	-40.2	176.3	-64	169.4	0	0	0	112.1	L22 V270 L271 N272 L279	L22-L274 HydrophobicContact CD2-CD2 4.41Å; V270-L274 HydrophobicContact CG1-CD1 4.29Å; V270-L274 WeakPolarHBondContact O-CD1 3.36Å; V270-L274 WeakPolarHBondContact O-CG 3.38Å; L271-L274 WeakPolarHBondContact O-CB 3.25Å; L271-L274 PolarHBondContact O-N 3.2Å; L271-L274 VanDerWaalsContact O-N 3.15Å; N272-L274 PolarHBondContact O-N 2.96Å; L274-L279 HydrophobicContact CD2-CD1 3.59Å; L274-L279 HydrophobicContact CG-CD1 4.29Å
275	V	86.8	Confident	77	Confident	11 Å²	11	39.7 Å²	39.7	7%	0.067	24%	0.24	C	C	.	.	H	α-helix	trans	-84.1	-23.7	-177.4	-59.2	0	0	0	0	113.8	L271 N272 G277	L271-V275 HydrophobicContact CD1-CG1 4.19Å; L271-V275 HydrophobicContact CG-CG1 4.21Å; L271-V275 WeakPolarHBondContact O-CG2 3.49Å; L271-V275 PolarHBondContact O-N 3.41Å; N272-V275 VanDerWaalsContact O-CG2 3.31Å; N272-V275 WeakPolarHBondContact O-CG2 3.48Å; N272-V275 PolarHBondContact O-N 3.18Å; V275-G277 VanDerWaalsContact C-N 3.26Å; V275-G277 PolarHBondContact O-N 3.17Å
276	T	80.4	Confident	73.9	Confident	7 Å²	7	42.3 Å²	42.3	4%	0.043	27%	0.267	C	S	.	.	H	α-helix	trans	-71	-24.1	-179.6	53.8	0	0	0	0	112.7	L48 L100 R104 N272 P273 Y278	L48-T276 HydrophobicContact CD2-CG2 3.49Å; L48-T276 VanDerWaalsContact CD2-CG2 3.49Å; L100-T276 HydrophobicContact CD2-CG2 4.15Å; R104-T276 PolarHBondContact NH2-O 3.13Å; N272-T276 WeakPolarHBondContact O-CG2 3.48Å; N272-T276 PolarHBondContact O-N 3.34Å; N272-T276 PolarHBondContact O-OG1 3.29Å; P273-T276 PolarHBondContact O-OG1 3.17Å; T276-Y278 WeakPolarHBondContact O-CD2 3.47Å
277	G	71.4	Confident	71.1	Confident	30 Å²	30	47.5 Å²	47.5	31%	0.309	30%	0.299	S	S	.	.	T	Hydrogen-bonded Turn	trans	82.2	18.2	170.9	0	0	0	0	0	115.1	V275 P283	V275-G277 VanDerWaalsContact C-N 3.26Å; V275-G277 PolarHBondContact O-N 3.17Å; G277-P283 WeakPolarHBondContact O-CD 3.26Å
278	Y	69.6	Low	68	Low	20 Å²	20	46.8 Å²	46.8	8%	0.078	30%	0.303	C	S	.	.			trans	-105.6	10.3	-179.3	-70.5	-80.1	0	0	0	114.6	L42 T45 T276 P283	L42-Y278 HydrophobicContact CD2-CD1 4.2Å; L42-Y278 HydrophobicContact CD2-CE1 3.46Å; L42-Y278 VanDerWaalsContact CD2-CE1 3.46Å; T45-Y278 HydrophobicContact CG2-CD2 3.47Å; T45-Y278 VanDerWaalsContact CG2-CD2 3.47Å; T45-Y278 HydrophobicContact CG2-CE2 3.81Å; T45-Y278 HydrophobicContact CG2-CG 4.16Å; T45-Y278 WeakPolarHBondContact OG1-CE2 3.39Å; T276-Y278 WeakPolarHBondContact O-CD2 3.47Å; Y278-P283 VanDerWaalsContact CD1-CD 3.46Å; Y278-P283 HydrophobicContact CD1-CG 3.99Å; Y278-P283 HydrophobicContact CE1-CG 3.57Å
279	L	65.4	Low	65	Low	52 Å²	52	51 Å²	51	27%	0.272	33%	0.332	S	S	.	.	S	Bend	trans	-74.4	127.6	168.6	-64.5	170.1	0	0	0	110	L22 L25 A26 P273 L274	L22-L279 HydrophobicContact CD2-CD1 3.92Å; L22-L279 HydrophobicContact CD2-CD2 4.11Å; L22-L279 WeakPolarHBondContact O-CD2 3.29Å; L25-L279 HydrophobicContact CB-CD2 4Å; A26-L279 HydrophobicContact CB-CD2 4.13Å; P273-L279 HydrophobicContact CB-CD2 4.36Å; P273-L279 WeakPolarHBondContact O-CD1 3.28Å; L274-L279 HydrophobicContact CD2-CD1 3.59Å; L274-L279 HydrophobicContact CG-CD1 4.29Å
280	G	56.3	Low	61.8	Low	66 Å²	66	58.7 Å²	58.7	68%	0.68	37%	0.37	S	S	*	.	S	Bend	trans	85.2	-140.9	176.2	0	0	0	0	0	114.8	G282	G280-G282 PolarHBondContact O-N 3.15Å
281	A	39.9	Very low	58.7	Low	98 Å²	98	62.5 Å²	62.5	81%	0.81	40%	0.395	S	S	*	.	S	Bend	trans	-64.7	8.7	-178.7	0	0	0	0	0	114.8
282	G	49.4	Very low	55.7	Low	14 Å²	14	72 Å²	72	14%	0.144	43%	0.428	C	S	.	.			trans	64.3	179.7	-178.4	0	0	0	0	0	114.1	H33 G280 G284	H33-G282 WeakPolarHBondContact NE2-CA 3.2Å; G280-G282 PolarHBondContact O-N 3.15Å; G282-G284 VanDerWaalsContact C-N 3.29Å; G282-G284 PolarHBondContact O-N 2.89Å
283	P	51.1	Low	52.8	Low	31 Å²	31	78.5 Å²	78.5	20%	0.201	47%	0.468	C	S	.	.	S	Bend	trans	-66.8	97.2	166.8	27	-26.5	0	0	0	106.9	G277 Y278 R285	G277-P283 WeakPolarHBondContact O-CD 3.26Å; Y278-P283 VanDerWaalsContact CD1-CD 3.46Å; Y278-P283 HydrophobicContact CD1-CG 3.99Å; Y278-P283 HydrophobicContact CE1-CG 3.57Å; P283-R285 PolarHBondContact O-N 3.5Å
284	G	41.3	Very low	50.1	Low	44 Å²	44	87.3 Å²	87.3	45%	0.454	51%	0.509	S	S	.	.			trans	-41.9	141.3	179.8	0	0	0	0	0	111.7	G282 G286	G282-G284 VanDerWaalsContact C-N 3.29Å; G282-G284 PolarHBondContact O-N 2.89Å; G284-G286 PolarHBondContact O-N 3.32Å
285	R	38.8	Very low	47.3	Very low	229 Å²	229	86.3 Å²	86.3	86%	0.864	52%	0.521	S	S	*	.	S	Bend	trans	-31.3	-4.8	-174.1	-90	176.6	167.6	-175.5	-3.7	120	P283 T287	P283-R285 PolarHBondContact O-N 3.5Å; R285-T287 PolarHBondContact O-N 3.37Å
286	G	33.7	Very low	44.7	Very low	55 Å²	55	89 Å²	89	57%	0.567	55%	0.551	S	S	*	*	T	Hydrogen-bonded Turn	trans	-80.7	10.5	-176.1	0	0	0	0	0	117.4	G284 V288	G284-G286 PolarHBondContact O-N 3.32Å; G286-V288 VanDerWaalsContact C-N 3.29Å
287	T	39.2	Very low	42.8	Very low	110 Å²	110	95.3 Å²	95.3	68%	0.675	59%	0.59	S	S	*	*	T	Hydrogen-bonded Turn	trans	-86.2	5.6	175	42.1	0	0	0	0	114.2	R285	R285-T287 PolarHBondContact O-N 3.37Å
288	V	33.9	Very low	41.1	Very low	66 Å²	66	101.8 Å²	101.8	40%	0.4	62%	0.615	S	S	.	*	S	Bend	trans	-90.9	100.6	163.1	-173	0	0	0	0	107.4	G286 M290	G286-V288 VanDerWaalsContact C-N 3.29Å; V288-M290 HydrophobicContact CG1-CG 4.09Å; V288-M290 PolarHBondContact O-N 2.97Å
289	C	35.8	Very low	39.6	Very low	90 Å²	90	109.7 Å²	109.7	61%	0.608	65%	0.653	S	S	*	*			trans	-57.7	95	155.5	-82.8	0	0	0	0	107.7
290	M	29.2	Very low	38.1	Very low	161 Å²	161	120.2 Å²	120.2	79%	0.793	70%	0.697	S	S	*	*			trans	-87.2	116.2	152.4	-79.2	-66.4	-168.6	0	0	106.1	V288 R292	V288-M290 HydrophobicContact CG1-CG 4.09Å; V288-M290 PolarHBondContact O-N 2.97Å; M290-R292 PolarHBondContact O-N 3.29Å
291	P	33.4	Very low	37.2	Very low	96 Å²	96	123 Å²	123	62%	0.623	70%	0.697	S	S	*	*			trans	-61.6	125.7	163.4	-9.3	24.4	0	0	0	107	T293	P291-T293 PolarHBondContact O-N 3.02Å; P291-T293 VanDerWaalsContact O-N 3.13Å
292	R	33.6	Very low	37.1	Very low	237 Å²	237	124.3 Å²	124.3	89%	0.894	69%	0.691	S	S	*	*			trans	-65.1	110.9	163.7	-161.6	175.1	-175.2	167.6	0	105.2	M290 Q294	M290-R292 PolarHBondContact O-N 3.29Å; R292-Q294 PolarHBondContact O-N 2.95Å
293	T	36	Very low	36.4	Very low	138 Å²	138	130.4 Å²	130.4	85%	0.847	72%	0.722	S	S	*	*			trans	-57.5	101.4	166.4	21.2	0	0	0	0	107.1	P291 G295	P291-T293 PolarHBondContact O-N 3.02Å; P291-T293 VanDerWaalsContact O-N 3.13Å; T293-G295 PolarHBondContact O-N 3.29Å
294	Q	35.4	Very low	35.6	Very low	187 Å²	187	136.2 Å²	136.2	87%	0.874	75%	0.752	S	S	*	*			trans	-70.7	106	156.8	-91.3	178.9	-23.2	0	0	105.3	R292 G296	R292-Q294 PolarHBondContact O-N 2.95Å; Q294-G296 PolarHBondContact O-N 3.11Å
295	G	33.3	Very low	35.2	Very low	71 Å²	71	142 Å²	142	73%	0.732	77%	0.771	S	S	*	*			trans	-54	120.2	170.3	0	0	0	0	0	108.6	T293 T297	T293-G295 PolarHBondContact O-N 3.29Å; G295-T297 PolarHBondContact O-N 3.29Å
296	G	31.4	Very low	35	Very low	68 Å²	68	136.2 Å²	136.2	70%	0.701	77%	0.765	S	S	*	*			trans	-61.1	122.2	169	0	0	0	0	0	108.7	Q294 I298	Q294-G296 PolarHBondContact O-N 3.11Å; G296-I298 PolarHBondContact O-N 3.21Å; G296-I298 VanDerWaalsContact O-N 3.09Å
297	T	41.6	Very low	35	Very low	139 Å²	139	142 Å²	142	85%	0.853	78%	0.779	S	S	*	*			trans	-52.7	106.5	154.2	32.7	0	0	0	0	108.5	G295	G295-T297 PolarHBondContact O-N 3.29Å
298	I	35.4	Very low	34.7	Very low	165 Å²	165	144.5 Å²	144.5	85%	0.846	79%	0.787	S	S	*	*			trans	-87.2	104.4	158.9	-65.4	178.9	0	0	0	105.8	G296	G296-I298 PolarHBondContact O-N 3.21Å; G296-I298 VanDerWaalsContact O-N 3.09Å
299	Q	37.8	Very low	34.8	Very low	186 Å²	186	151 Å²	151	87%	0.869	82%	0.819	S	S	*	*			trans	-94.1	111.5	163.1	-150.3	-178.3	6.9	0	0	106.2
300	K	34.5	Very low	34.7	Very low	274 Å²	274	156.5 Å²	156.5	100%	1.191	84%	0.839	S	S	*	*			trans	-176.2	0	145.1	-102.3	-179.1	-173.8	-172	0	108.9

Retrieved 300 of 300 residues in 88.5 ms (Link to these results)

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