A0A061I2R6_CRIGR Loading...

G-protein coupled receptor 22

Orphan G-protein coupled receptor. Seems to act through a G(i)/G(o) mediated pathway. May be involved in ciliogenesis.

AlphaFold DB , UniProt , Accession A0A061I2R6, Species CRIGR (Cricetulus griseus, Chinese hamster), Gene Gpr22, Length 469 aa.

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	33.2	Very low	37.9	Very low	254 Å²	254	116.3 Å²	116.3	100%	1.251	63%	0.63	S	S	*	*				0	90.7	0	-100.5	175	144.6	0	0	108.7
2	S	32.1	Very low	38.6	Very low	105 Å²	105	116.2 Å²	116.2	73%	0.734	63%	0.628	S	S	*	*			trans	-117.4	113.4	172.4	39.5	0	0	0	0	108	L4	S2-L4 PolarHBondContact O-N 2.91Å; S2-L4 VanDerWaalsContact O-N 3.13Å
3	K	36.6	Very low	38.9	Very low	212 Å²	212	119.5 Å²	119.5	92%	0.922	63%	0.626	S	S	*	*			trans	-71.1	100.2	173.1	-75.3	177	177.4	174.4	0	107.9	S5	K3-S5 PolarHBondContact O-N 3.12Å
4	L	39.1	Very low	39.1	Very low	126 Å²	126	120 Å²	120	66%	0.66	62%	0.621	S	S	*	*			trans	-72	108.7	160	-101.2	86	0	0	0	107.6	S2	S2-L4 PolarHBondContact O-N 2.91Å; S2-L4 VanDerWaalsContact O-N 3.13Å
5	S	39.1	Very low	39	Very low	59 Å²	59	118.4 Å²	118.4	41%	0.413	62%	0.618	S	S	.	*			trans	-71.5	146.5	170.6	177.9	0	0	0	0	109.4	K3 T7 S8	K3-S5 PolarHBondContact O-N 3.12Å; S5-T7 PolarHBondContact O-N 3Å; S5-T7 PolarHBondContact OG-N 2.91Å; S5-T7 PolarHBondContact OG-OG1 3.37Å; S5-S8 WeakPolarHBondContact O-CA 3.15Å; S5-S8 VanDerWaalsContact O-CB 3.3Å; S5-S8 WeakPolarHBondContact O-CB 3.42Å; S5-S8 PolarHBondContact O-N 3.38Å
6	M	35.5	Very low	39	Very low	156 Å²	156	114.8 Å²	114.8	77%	0.768	61%	0.611	S	S	*	*	H	α-helix	trans	-52.7	-25.4	171.8	-159.1	160.1	79.5	0	0	112.2	C9 I10	M6-C9 PolarHBondContact O-N 3.27Å; M6-I10 WeakPolarHBondContact O-CG1 3.31Å; M6-I10 PolarHBondContact O-N 2.73Å
7	T	37.9	Very low	38.8	Very low	80 Å²	80	113.9 Å²	113.9	49%	0.491	60%	0.604	S	S	.	*	H	α-helix	trans	-64.6	-34.9	172.2	-31.8	0	0	0	0	113.1	S5 I10 N11	S5-T7 PolarHBondContact O-N 3Å; S5-T7 PolarHBondContact OG-N 2.91Å; S5-T7 PolarHBondContact OG-OG1 3.37Å; T7-I10 PolarHBondContact O-N 3.31Å; T7-N11 WeakPolarHBondContact O-CB 3.38Å; T7-N11 VanDerWaalsContact O-CG 3.22Å; T7-N11 PolarHBondContact O-N 3.22Å; T7-N11 PolarHBondContact O-ND2 3.32Å
8	S	38.3	Very low	38.8	Very low	51 Å²	51	113.7 Å²	113.7	36%	0.357	61%	0.608	S	S	.	*	H	α-helix	trans	-67.2	-37.3	176.5	-64.6	0	0	0	0	111.5	S5 N11 L12	S5-S8 WeakPolarHBondContact O-CA 3.15Å; S5-S8 VanDerWaalsContact O-CB 3.3Å; S5-S8 WeakPolarHBondContact O-CB 3.42Å; S5-S8 PolarHBondContact O-N 3.38Å; S8-N11 PolarHBondContact O-N 3.49Å; S8-L12 WeakPolarHBondContact O-CB 3.43Å; S8-L12 PolarHBondContact O-N 3.31Å
9	C	40.3	Very low	38.5	Very low	66 Å²	66	111.6 Å²	111.6	45%	0.446	60%	0.603	S	S	.	*	H	α-helix	trans	-67.9	-40	174.6	-67.1	0	0	0	0	112.3	M6 N11 L12 W13	M6-C9 PolarHBondContact O-N 3.27Å; C9-N11 VanDerWaalsContact C-N 3.31Å; C9-N11 PolarHBondContact O-N 2.99Å; C9-L12 PolarHBondContact O-N 2.68Å; C9-W13 WeakPolarHBondContact O-CB 3.29Å; C9-W13 PolarHBondContact O-N 3.35Å
10	I	46	Very low	38.6	Very low	85 Å²	85	113 Å²	113	44%	0.436	61%	0.605	S	S	.	*	H	α-helix	trans	-65.2	-37.4	175.3	-66.2	166.5	0	0	0	111	M6 T7 W13 K14	M6-I10 WeakPolarHBondContact O-CG1 3.31Å; M6-I10 PolarHBondContact O-N 2.73Å; T7-I10 PolarHBondContact O-N 3.31Å; I10-W13 PolarHBondContact O-N 2.97Å; I10-K14 PolarHBondContact O-N 3.43Å; I10-K14 VanDerWaalsContact O-N 3.07Å
11	N	39.1	Very low	38.6	Very low	85 Å²	85	116 Å²	116	46%	0.455	61%	0.613	S	S	.	*	H	α-helix	trans	-70.8	-42.8	178.6	-73.8	-19.2	0	0	0	111.7	T7 S8 C9 W13 K14 T15	T7-N11 WeakPolarHBondContact O-CB 3.38Å; T7-N11 VanDerWaalsContact O-CG 3.22Å; T7-N11 PolarHBondContact O-N 3.22Å; T7-N11 PolarHBondContact O-ND2 3.32Å; S8-N11 PolarHBondContact O-N 3.49Å; C9-N11 VanDerWaalsContact C-N 3.31Å; C9-N11 PolarHBondContact O-N 2.99Å; N11-W13 VanDerWaalsContact C-N 3.25Å; N11-W13 PolarHBondContact O-N 3.06Å; N11-K14 PolarHBondContact O-N 3.07Å; N11-K14 VanDerWaalsContact O-N 3.15Å; N11-T15 PolarHBondContact O-N 3.05Å; N11-T15 PolarHBondContact O-OG1 3.27Å
12	L	45.5	Very low	38.6	Very low	115 Å²	115	107.8 Å²	107.8	60%	0.602	58%	0.58	S	S	*	*	H	α-helix	trans	-57.4	-37.7	171.9	-93.2	146.6	0	0	0	112.4	S8 C9 T15 A16	S8-L12 WeakPolarHBondContact O-CB 3.43Å; S8-L12 PolarHBondContact O-N 3.31Å; C9-L12 PolarHBondContact O-N 2.68Å; L12-T15 PolarHBondContact O-N 2.82Å; L12-T15 PolarHBondContact O-OG1 3.26Å; L12-A16 PolarHBondContact O-N 3.37Å; L12-A16 VanDerWaalsContact O-N 3.12Å
13	W	43.6	Very low	38.7	Very low	159 Å²	159	109.3 Å²	109.3	60%	0.602	58%	0.575	S	S	*	*	H	α-helix	trans	-66.6	-41	175	-178.7	71.1	0	0	0	112.9	C9 I10 N11 A16 M17	C9-W13 WeakPolarHBondContact O-CB 3.29Å; C9-W13 PolarHBondContact O-N 3.35Å; I10-W13 PolarHBondContact O-N 2.97Å; N11-W13 VanDerWaalsContact C-N 3.25Å; N11-W13 PolarHBondContact O-N 3.06Å; W13-A16 PolarHBondContact O-N 3.32Å; W13-M17 HydrophobicContact CH2-CE 4.01Å; W13-M17 HydrophobicContact CZ2-CE 3.81Å; W13-M17 PolarHBondContact O-N 3.36Å; W13-M17 VanDerWaalsContact O-N 3.16Å
14	K	40.4	Very low	38.7	Very low	127 Å²	127	107.8 Å²	107.8	55%	0.552	57%	0.569	S	S	*	*	H	α-helix	trans	-64.6	-40.6	175.2	-78	-176.1	177.4	-178.9	0	112.3	I10 N11 M17 V18	I10-K14 PolarHBondContact O-N 3.43Å; I10-K14 VanDerWaalsContact O-N 3.07Å; N11-K14 PolarHBondContact O-N 3.07Å; N11-K14 VanDerWaalsContact O-N 3.15Å; K14-M17 PolarHBondContact O-N 3.43Å; K14-V18 WeakPolarHBondContact O-CG2 3.16Å; K14-V18 PolarHBondContact O-N 3.42Å
15	T	38.9	Very low	38.6	Very low	96 Å²	96	105.3 Å²	105.3	59%	0.589	57%	0.567	S	S	*	*	H	α-helix	trans	-66.8	-37.8	178.3	-1.6	0	0	0	0	112.1	N11 L12 V18 S19	N11-T15 PolarHBondContact O-N 3.05Å; N11-T15 PolarHBondContact O-OG1 3.27Å; L12-T15 PolarHBondContact O-N 2.82Å; L12-T15 PolarHBondContact O-OG1 3.26Å; T15-V18 PolarHBondContact O-N 2.96Å; T15-S19 PolarHBondContact O-N 3.25Å
16	A	38.2	Very low	38.6	Very low	60 Å²	60	107.4 Å²	107.4	50%	0.496	58%	0.577	S	S	.	*	H	α-helix	trans	-64	-41.1	176	0	0	0	0	0	112.4	L12 W13 S19 Q20	L12-A16 PolarHBondContact O-N 3.37Å; L12-A16 VanDerWaalsContact O-N 3.12Å; W13-A16 PolarHBondContact O-N 3.32Å; A16-S19 PolarHBondContact O-N 2.91Å; A16-Q20 PolarHBondContact O-N 3.5Å
17	M	35.8	Very low	38.6	Very low	101 Å²	101	104 Å²	104	50%	0.498	57%	0.574	S	S	.	*	H	α-helix	trans	-66.5	-35.3	177.4	-79.4	-100.5	-94.3	0	0	113.6	W13 K14	W13-M17 HydrophobicContact CH2-CE 4.01Å; W13-M17 HydrophobicContact CZ2-CE 3.81Å; W13-M17 PolarHBondContact O-N 3.36Å; W13-M17 VanDerWaalsContact O-N 3.16Å; K14-M17 PolarHBondContact O-N 3.43Å
18	V	38.8	Very low	38.5	Very low	110 Å²	110	107.4 Å²	107.4	67%	0.667	59%	0.589	S	S	*	*	H	α-helix	trans	-72.2	-38.3	178.7	173.7	0	0	0	0	111.6	K14 T15 Q20 K21	K14-V18 WeakPolarHBondContact O-CG2 3.16Å; K14-V18 PolarHBondContact O-N 3.42Å; T15-V18 PolarHBondContact O-N 2.96Å; V18-Q20 VanDerWaalsContact C-N 3.29Å; V18-Q20 PolarHBondContact O-N 3.35Å; V18-K21 PolarHBondContact O-N 3.26Å
19	S	32.4	Very low	38.4	Very low	74 Å²	74	116.2 Å²	116.2	52%	0.517	61%	0.614	S	S	.	*	H	α-helix	trans	-62.2	-36.3	176	-168.8	0	0	0	0	112.4	T15 A16 K21 S22 H23	T15-S19 PolarHBondContact O-N 3.25Å; A16-S19 PolarHBondContact O-N 2.91Å; S19-K21 PolarHBondContact O-N 3.09Å; S19-S22 PolarHBondContact O-N 2.66Å; S19-H23 PolarHBondContact O-N 3.32Å
20	Q	40.9	Very low	38	Very low	139 Å²	139	116.7 Å²	116.7	65%	0.65	63%	0.631	S	S	*	*	H	α-helix	trans	-71.3	-27.5	-178.7	-142.7	174.7	9.8	0	0	113.6	A16 V18 S22 K24	A16-Q20 PolarHBondContact O-N 3.5Å; V18-Q20 VanDerWaalsContact C-N 3.29Å; V18-Q20 PolarHBondContact O-N 3.35Å; Q20-S22 VanDerWaalsContact C-N 3.33Å; Q20-K24 PolarHBondContact O-N 2.96Å
21	K	38.7	Very low	37.4	Very low	177 Å²	177	120.1 Å²	120.1	77%	0.77	65%	0.65	S	S	*	*	H	α-helix	trans	-73.6	-26.7	176.5	-143.3	177.4	-173.5	-177	0	112.3	V18 S19	V18-K21 PolarHBondContact O-N 3.26Å; S19-K21 PolarHBondContact O-N 3.09Å
22	S	32.8	Very low	37.1	Very low	80 Å²	80	122.2 Å²	122.2	56%	0.559	67%	0.666	S	S	*	*	H	α-helix	trans	-76.1	-42.6	176.5	-171.3	0	0	0	0	112	S19 Q20 K24 A25 T26	S19-S22 PolarHBondContact O-N 2.66Å; Q20-S22 VanDerWaalsContact C-N 3.33Å; S22-K24 VanDerWaalsContact C-N 3.34Å; S22-K24 PolarHBondContact O-N 2.8Å; S22-A25 PolarHBondContact O-N 2.99Å; S22-T26 PolarHBondContact O-OG1 2.85Å
23	H	35	Very low	36.3	Very low	137 Å²	137	123.6 Å²	123.6	63%	0.634	67%	0.674	S	S	*	*	H	α-helix	trans	-67.4	-28.5	177.3	-93.8	-79	0	0	0	114.3	S19 A25 T26 A27	S19-H23 PolarHBondContact O-N 3.32Å; H23-A25 VanDerWaalsContact C-N 3.32Å; H23-T26 PolarHBondContact O-OG1 2.86Å; H23-A27 PolarHBondContact O-N 3.29Å
24	K	37.3	Very low	35.6	Very low	180 Å²	180	121.8 Å²	121.8	78%	0.783	68%	0.684	S	S	*	*	H	α-helix	trans	-76	-18.7	176.7	-134.8	172.2	-172.6	175.8	0	113.3	Q20 S22	Q20-K24 PolarHBondContact O-N 2.96Å; S22-K24 VanDerWaalsContact C-N 3.34Å; S22-K24 PolarHBondContact O-N 2.8Å
25	A	36.9	Very low	35	Very low	75 Å²	75	121.4 Å²	121.4	62%	0.62	70%	0.698	S	S	*	*	H	α-helix	trans	-86.1	-28.8	178.1	0	0	0	0	0	112.9	S22 H23	S22-A25 PolarHBondContact O-N 2.99Å; H23-A25 VanDerWaalsContact C-N 3.32Å
26	T	38.6	Very low	34.8	Very low	102 Å²	102	126.4 Å²	126.4	63%	0.626	71%	0.711	S	S	*	*	H	α-helix	trans	-83.4	-25.5	177.9	29.2	0	0	0	0	113.7	S22 H23 N28	S22-T26 PolarHBondContact O-OG1 2.85Å; H23-T26 PolarHBondContact O-OG1 2.86Å; T26-N28 VanDerWaalsContact C-N 3.29Å; T26-N28 PolarHBondContact O-N 3.38Å
27	A	35.9	Very low	34.2	Very low	86 Å²	86	135.6 Å²	135.6	71%	0.711	73%	0.733	S	S	*	*	T	Hydrogen-bonded Turn	trans	-75.9	-8.8	-179.8	0	0	0	0	0	114.9	H23	H23-A27 PolarHBondContact O-N 3.29Å
28	N	35.5	Very low	33.8	Very low	150 Å²	150	139.2 Å²	139.2	80%	0.802	75%	0.751	S	S	*	*	T	Hydrogen-bonded Turn	trans	-102.4	12.4	-175.5	-141.9	21	0	0	0	114.2	T26	T26-N28 VanDerWaalsContact C-N 3.29Å; T26-N28 PolarHBondContact O-N 3.38Å
29	R	35.3	Very low	33.2	Very low	236 Å²	236	140 Å²	140	89%	0.891	76%	0.759	S	S	*	*	S	Bend	trans	-132.3	88.8	175	-101	-174.2	-174.9	179.7	2.5	110.1
30	G	33.1	Very low	32.9	Very low	76 Å²	76	145.9 Å²	145.9	78%	0.784	78%	0.776	S	S	*	*			trans	153.5	74.6	166.3	0	0	0	0	0	113.8
31	N	32.4	Very low	32.3	Very low	158 Å²	158	144.2 Å²	144.2	85%	0.845	78%	0.78	S	S	*	*			trans	-148.3	95.2	153.2	-149.6	9.7	0	0	0	110.7
32	T	33.2	Very low	32.2	Very low	128 Å²	128	141.5 Å²	141.5	79%	0.785	78%	0.781	S	S	*	*			trans	-152.3	130.3	151.8	31.7	0	0	0	0	109.5
33	N	28.8	Very low	32	Very low	145 Å²	145	143.5 Å²	143.5	78%	0.775	79%	0.789	S	S	*	*			trans	92.9	118.8	154.1	-64.8	-13.2	0	0	0	122.5
34	C	28.4	Very low	31.5	Very low	120 Å²	120	145.6 Å²	145.6	81%	0.811	80%	0.804	S	S	*	*			trans	65	119.6	131.7	-73.2	0	0	0	0	120.8
35	S	28.3	Very low	30.9	Very low	120 Å²	120	145.1 Å²	145.1	84%	0.839	80%	0.804	S	S	*	*				156.2	150.5	82	-153.2	0	0	0	0	112.8
36	K	35.2	Very low	30.4	Very low	201 Å²	201	149.2 Å²	149.2	87%	0.874	81%	0.814	S	S	*	*			trans	-64.1	144.8	174	-68.8	169.6	173.6	175.1	0	112.5
37	R	24.9	Very low	29.7	Very low	252 Å²	252	151.6 Å²	151.6	95%	0.951	82%	0.823	S	S	*	*			trans	-163.1	128.5	142.6	-113.8	175.8	-151.6	-145.4	4	113.5
38	M	27.7	Very low	29.1	Very low	177 Å²	177	155.7 Å²	155.7	87%	0.872	83%	0.83	S	S	*	*			trans	-65.1	155.4	161.8	-84.4	166.3	153.9	0	0	111.8
39	C	25.6	Very low	28.7	Very low	126 Å²	126	157.7 Å²	157.7	85%	0.851	83%	0.834	S	S	*	*			trans	-172.9	119.6	131	-100.1	0	0	0	0	113.7
40	F	25.8	Very low	28.2	Very low	199 Å²	199	151.2 Å²	151.2	87%	0.873	83%	0.825	S	S	*	*			trans	12.5	140.1	146	-83.5	-97	0	0	0	124.5
41	S	29.7	Very low	27.9	Very low	104 Å²	104	153.5 Å²	153.5	73%	0.727	82%	0.824	S	S	*	*			trans	-74.7	168.9	156.3	-65.1	0	0	0	0	113.4
42	P	36.1	Very low	28.1	Very low	120 Å²	120	150.5 Å²	150.5	78%	0.779	82%	0.815	S	S	*	*				-141.7	134.7	108	31.7	-14.5	0	0	0	113.2
43	V	28	Very low	27.9	Very low	122 Å²	122	151.3 Å²	151.3	74%	0.739	82%	0.815	S	S	*	*				56.3	113.7	95	-175.1	0	0	0	0	115.5
44	L	24.7	Very low	28	Very low	181 Å²	181	152.5 Å²	152.5	95%	0.948	82%	0.819	S	S	*	*			trans	-138.7	126.4	144.5	-141.3	99.6	0	0	0	108.8
45	Q	24.2	Very low	28.2	Very low	169 Å²	169	152.2 Å²	152.2	79%	0.79	81%	0.814	S	S	*	*			trans	-126.4	170.7	179.5	-151	-179.4	-1.8	0	0	107.7
46	I	27.1	Very low	28.4	Very low	161 Å²	161	152.1 Å²	152.1	83%	0.826	81%	0.808	S	S	*	*			trans	116.3	125.6	171.4	-61.2	160.5	0	0	0	110.7
47	N	23.2	Very low	28.2	Very low	153 Å²	153	152.5 Å²	152.5	82%	0.818	80%	0.804	S	S	*	*			cis	-154.2	166	6.6	-145.3	-8.8	0	0	0	112.8
48	M	24.6	Very low	28.7	Very low	171 Å²	171	146.4 Å²	146.4	84%	0.842	79%	0.79	S	S	*	*			trans	-82.2	151.8	177.1	-114.1	-177.8	139	0	0	115.1
49	Q	27.1	Very low	29.1	Very low	193 Å²	193	143.2 Å²	143.2	90%	0.902	78%	0.776	S	S	*	*			trans	162.4	139.6	136.9	-91.4	174.8	2.4	0	0	107.6
50	S	24.9	Very low	29.7	Very low	99 Å²	99	143 Å²	143	69%	0.692	77%	0.766	S	S	*	*			cis	-171.8	159.8	-5.6	72.4	0	0	0	0	107.5
51	V	26.6	Very low	30.4	Very low	125 Å²	125	139.3 Å²	139.3	76%	0.758	76%	0.755	S	S	*	*			trans	83.3	106.5	152.1	-176.7	0	0	0	0	119
52	S	35.1	Very low	30.7	Very low	94 Å²	94	139.8 Å²	139.8	66%	0.657	75%	0.75	S	S	*	*			trans	32.5	115.6	147.3	65.3	0	0	0	0	120
53	N	29.3	Very low	30.9	Very low	146 Å²	146	140.2 Å²	140.2	78%	0.781	74%	0.744	S	S	*	*				-152.3	114	126.6	-91.2	-26.3	0	0	0	108.6	T55	N53-T55 HydrophobicContact CB-CG2 4.4Å; N53-T55 PolarHBondContact O-N 3.5Å
54	I	32.4	Very low	31.4	Very low	169 Å²	169	138.5 Å²	138.5	87%	0.867	73%	0.73	S	S	*	*			trans	-69.8	89.6	160.9	-64.3	166.2	0	0	0	104.8
55	T	30.8	Very low	32.1	Very low	115 Å²	115	133.9 Å²	133.9	71%	0.706	71%	0.71	S	S	*	*			trans	-87.4	107.2	160.8	47.1	0	0	0	0	106.3	N53 R57	N53-T55 HydrophobicContact CB-CG2 4.4Å; N53-T55 PolarHBondContact O-N 3.5Å; T55-R57 PolarHBondContact O-N 2.86Å
56	V	33.5	Very low	32.7	Very low	118 Å²	118	131.7 Å²	131.7	72%	0.715	70%	0.704	S	S	*	*			trans	-43.4	113.6	158.3	173.3	0	0	0	0	106.4	D58	V56-D58 PolarHBondContact O-N 3.28Å
57	R	31.3	Very low	33.3	Very low	209 Å²	209	130.4 Å²	130.4	79%	0.789	70%	0.696	S	S	*	*			trans	-71.7	112.8	174.5	-152	167.8	-168.5	141.8	-0.8	104.9	T55 D59	T55-R57 PolarHBondContact O-N 2.86Å; R57-D59 PolarHBondContact O-N 2.83Å
58	D	34.8	Very low	33.9	Very low	123 Å²	123	131.5 Å²	131.5	66%	0.658	69%	0.69	S	S	*	*			trans	-63.9	84.9	167.7	-77.6	-44.4	0	0	0	107.9	V56 I60	V56-D58 PolarHBondContact O-N 3.28Å; D58-I60 PolarHBondContact O-N 3.09Å
59	D	35.5	Very low	34.5	Very low	110 Å²	110	130.7 Å²	130.7	59%	0.588	68%	0.684	S	S	*	*	T	Hydrogen-bonded Turn	trans	-72.2	27.7	169.9	-74.3	-32.3	0	0	0	111.6	R57	R57-D59 PolarHBondContact O-N 2.83Å
60	I	40.2	Very low	35.3	Very low	122 Å²	122	124.3 Å²	124.3	63%	0.626	66%	0.664	S	S	*	*	T	Hydrogen-bonded Turn	trans	-101.9	-24.1	-178.6	-61.1	-176.9	0	0	0	111.7	D58	D58-I60 PolarHBondContact O-N 3.09Å
61	D	38.5	Very low	36.7	Very low	121 Å²	121	123 Å²	123	65%	0.647	65%	0.649	S	S	*	*	H	α-helix	trans	-86.8	-17.6	-177.9	-75.5	-24.8	0	0	0	114.4	T65	D61-T65 PolarHBondContact O-OG1 3.03Å
62	D	36.3	Very low	38.4	Very low	115 Å²	115	121.1 Å²	121.1	62%	0.615	64%	0.641	S	S	*	*	H	α-helix	trans	-86.6	-12.7	179.2	-97.2	-30.4	0	0	0	113.7	N66	D62-N66 PolarHBondContact O-ND2 2.98Å
63	I	41	Very low	40.2	Very low	129 Å²	129	117.9 Å²	117.9	66%	0.662	62%	0.615	S	S	*	*	H	α-helix	trans	-87.2	-37.5	176.8	-61.2	177.8	0	0	0	110.9
64	D	38.9	Very low	42.9	Very low	85 Å²	85	114 Å²	114	46%	0.455	60%	0.598	S	S	.	*	H	α-helix	trans	-72.2	-35.3	177.1	-95.7	-21.5	0	0	0	111.9	N66 M67 Y68	D64-N66 VanDerWaalsContact C-N 3.34Å; D64-N66 PolarHBondContact O-N 2.86Å; D64-M67 PolarHBondContact O-N 3.06Å; D64-Y68 WeakPolarHBondContact O-CD2 3.2Å; D64-Y68 WeakPolarHBondContact O-CE2 3.28Å
65	T	39.5	Very low	45.4	Very low	85 Å²	85	112.2 Å²	112.2	52%	0.521	59%	0.589	S	S	.	*	H	α-helix	trans	-71.1	-28.8	-175.9	-45.9	0	0	0	0	113	D61	D61-T65 PolarHBondContact O-OG1 3.03Å
66	N	36.7	Very low	48.2	Very low	123 Å²	123	111.2 Å²	111.2	66%	0.658	59%	0.587	S	S	*	*	H	α-helix	trans	-86	-10.6	179.4	-72.4	-54.2	0	0	0	113.9	D62 D64	D62-N66 PolarHBondContact O-ND2 2.98Å; D64-N66 VanDerWaalsContact C-N 3.34Å; D64-N66 PolarHBondContact O-N 2.86Å
67	M	38.3	Very low	50.8	Low	134 Å²	134	107.5 Å²	107.5	66%	0.66	56%	0.561	S	S	*	*	H	α-helix	trans	-86.9	-17.9	177	-165.2	168.9	66.9	0	0	113.2	D64	D64-M67 PolarHBondContact O-N 3.06Å
68	Y	36.7	Very low	53.6	Low	175 Å²	175	99.4 Å²	99.4	69%	0.686	53%	0.533	S	S	*	.	S	Bend	trans	-89.9	-6	176.5	-66.5	-74.2	0	0	0	114.3	D64 A70	D64-Y68 WeakPolarHBondContact O-CD2 3.2Å; D64-Y68 WeakPolarHBondContact O-CE2 3.28Å; Y68-A70 VanDerWaalsContact C-N 3.28Å; Y68-A70 PolarHBondContact O-N 3.28Å
69	Q	37.7	Very low	56.4	Low	155 Å²	155	98 Å²	98	72%	0.724	53%	0.528	S	S	*	.			trans	-91	35.3	-174.4	-152.5	93.1	6.9	0	0	113.2
70	A	43	Very low	59.2	Low	58 Å²	58	95.8 Å²	95.8	48%	0.479	52%	0.521	S	S	.	.	S	Bend	trans	-128.2	81.2	171	0	0	0	0	0	109.3	Y68 S72	Y68-A70 VanDerWaalsContact C-N 3.28Å; Y68-A70 PolarHBondContact O-N 3.28Å; A70-S72 PolarHBondContact O-N 3.48Å; A70-S72 PolarHBondContact O-OG 2.94Å
71	L	55.1	Low	61.8	Low	73 Å²	73	90.5 Å²	90.5	38%	0.382	49%	0.494	S	S	.	.			trans	25.8	57.1	165.2	-147.4	85.2	0	0	0	117.6	T237	L71-T237 HydrophobicContact CD1-CG2 3.54Å
72	S	61.1	Low	64.4	Low	85 Å²	85	85.8 Å²	85.8	59%	0.594	47%	0.47	S	S	*	.	P	Polyproline II helix	trans	-90.7	116.3	169.7	-68.5	0	0	0	0	109.4	A70	A70-S72 PolarHBondContact O-N 3.48Å; A70-S72 PolarHBondContact O-OG 2.94Å
73	Y	74.4	Confident	67.3	Low	26 Å²	26	82.4 Å²	82.4	10%	0.102	46%	0.462	C	S	.	.	P	Polyproline II helix	trans	-52.9	148.6	169.3	-65.6	-80.4	0	0	0	109.6	L75 F77 K383 L386	Y73-L75 PolarHBondContact O-N 3.46Å; Y73-F77 AromaticContact CD1-CD1 3.99Å; Y73-F77 HydrophobicContact CD1-CD1 3.99Å; Y73-F77 AromaticContact CD1-CE1 3.87Å; Y73-F77 HydrophobicContact CD1-CE1 3.87Å; Y73-F77 HydrophobicContact CE1-CE1 4.36Å; Y73-F77 HydrophobicContact CG-CD1 4.09Å; Y73-F77 HydrophobicContact CG-CE1 4.26Å; Y73-K383 HydrophobicContact CD1-CG 4.24Å; Y73-K383 HydrophobicContact CE1-CG 4.13Å; Y73-L386 HydrophobicContact CE1-CD1 3.81Å; Y73-L386 HydrophobicContact CE2-CD1 4.21Å; Y73-L386 WeakPolarHBondContact OH-CD1 3.46Å
74	P	84.4	Confident	69.9	Low	65 Å²	65	81.7 Å²	81.7	42%	0.422	45%	0.454	S	S	.	.	P	Polyproline II helix	trans	-56.1	134.8	177.4	20.2	-29.1	0	0	0	109.9	S76 F77 Q78	P74-S76 PolarHBondContact O-N 2.97Å; P74-F77 HydrophobicContact CG-CB 3.8Å; P74-F77 WeakPolarHBondContact O-CA 3.47Å; P74-F77 VanDerWaalsContact O-CB 3.26Å; P74-F77 WeakPolarHBondContact O-CB 3.36Å; P74-F77 PolarHBondContact O-N 2.78Å; P74-Q78 PolarHBondContact O-N 3.23Å; P74-Q78 VanDerWaalsContact O-N 3.17Å
75	L	85.4	Confident	72.6	Confident	130 Å²	130	77.7 Å²	77.7	68%	0.681	43%	0.432	S	S	*	.	H	α-helix	trans	-52.4	-38.4	-171.6	-176.1	67.4	0	0	0	112.8	Y73 F77 Q78 V79	Y73-L75 PolarHBondContact O-N 3.46Å; L75-F77 VanDerWaalsContact C-N 3.32Å; L75-F77 PolarHBondContact O-N 3.22Å; L75-Q78 PolarHBondContact O-N 3.41Å; L75-V79 HydrophobicContact CD1-CG2 4.15Å; L75-V79 HydrophobicContact CG-CG2 4.24Å; L75-V79 WeakPolarHBondContact O-CB 3.25Å; L75-V79 VanDerWaalsContact O-CG2 3.28Å; L75-V79 WeakPolarHBondContact O-CG2 3.28Å; L75-V79 PolarHBondContact O-N 3.39Å
76	S	89.5	Confident	75.4	Confident	95 Å²	95	78.3 Å²	78.3	66%	0.664	43%	0.431	S	S	*	.	H	α-helix	trans	-60.5	-38.6	176.4	56.6	0	0	0	0	113.1	P74 S80	P74-S76 PolarHBondContact O-N 2.97Å; S76-S80 WeakPolarHBondContact O-CB 3.43Å; S76-S80 PolarHBondContact O-N 2.92Å
77	F	89.4	Confident	78.2	Confident	39 Å²	39	76.6 Å²	76.6	17%	0.171	42%	0.421	C	S	.	.	H	α-helix	trans	-68.3	-47.7	176.5	-179.4	-93.9	0	0	0	111.1	Y73 P74 L75 S80 L81 K383 L386 C387	Y73-F77 AromaticContact CD1-CD1 3.99Å; Y73-F77 HydrophobicContact CD1-CD1 3.99Å; Y73-F77 AromaticContact CD1-CE1 3.87Å; Y73-F77 HydrophobicContact CD1-CE1 3.87Å; Y73-F77 HydrophobicContact CE1-CE1 4.36Å; Y73-F77 HydrophobicContact CG-CD1 4.09Å; Y73-F77 HydrophobicContact CG-CE1 4.26Å; P74-F77 HydrophobicContact CG-CB 3.8Å; P74-F77 WeakPolarHBondContact O-CA 3.47Å; P74-F77 VanDerWaalsContact O-CB 3.26Å; P74-F77 WeakPolarHBondContact O-CB 3.36Å; P74-F77 PolarHBondContact O-N 2.78Å; L75-F77 VanDerWaalsContact C-N 3.32Å; L75-F77 PolarHBondContact O-N 3.22Å; F77-S80 PolarHBondContact O-N 2.91Å; F77-L81 HydrophobicContact CE1-CD2 4.01Å; F77-L81 HydrophobicContact CZ-CD2 4.02Å; F77-L81 VanDerWaalsContact O-CB 3.31Å; F77-L81 WeakPolarHBondContact O-CB 3.46Å; F77-L81 PolarHBondContact O-N 3.35Å; F77-K383 HydrophobicContact CE2-CB 4.48Å; F77-K383 HydrophobicContact CZ-CB 4.28Å; F77-L386 HydrophobicContact CE1-CD1 4.28Å; F77-L386 HydrophobicContact CZ-CB 4.36Å; F77-C387 VanDerWaalsContact CE2-SG 3.55Å
78	Q	89.9	Confident	80.9	Confident	40 Å²	40	71 Å²	71	19%	0.187	39%	0.393	C	S	.	.	H	α-helix	trans	-61.2	-48.2	179.4	-178.5	179.1	-12.2	0	0	111.9	P74 L75 T82 L140 L141	P74-Q78 PolarHBondContact O-N 3.23Å; P74-Q78 VanDerWaalsContact O-N 3.17Å; L75-Q78 PolarHBondContact O-N 3.41Å; Q78-T82 WeakPolarHBondContact O-CB 3.24Å; Q78-T82 PolarHBondContact O-N 2.94Å; Q78-T82 PolarHBondContact O-OG1 3.35Å; Q78-L140 WeakPolarHBondContact CG-O 3.21Å; Q78-L140 PolarHBondContact NE2-O 2.85Å; Q78-L141 HydrophobicContact CG-CD2 3.78Å
79	V	92.4	Very high	83.8	Confident	94 Å²	94	64.2 Å²	64.2	57%	0.57	37%	0.368	S	S	*	.	H	α-helix	trans	-63.2	-45.1	178.4	171.8	0	0	0	0	110.9	L75 G83	L75-V79 HydrophobicContact CD1-CG2 4.15Å; L75-V79 HydrophobicContact CG-CG2 4.24Å; L75-V79 WeakPolarHBondContact O-CB 3.25Å; L75-V79 VanDerWaalsContact O-CG2 3.28Å; L75-V79 WeakPolarHBondContact O-CG2 3.28Å; L75-V79 PolarHBondContact O-N 3.39Å; V79-G83 PolarHBondContact O-N 2.83Å
80	S	94.9	Very high	86.6	Confident	62 Å²	62	61.6 Å²	61.6	43%	0.434	36%	0.363	S	S	.	.	H	α-helix	trans	-62.2	-50.3	179.7	-178.8	0	0	0	0	111.7	S76 F77 G83 F84	S76-S80 WeakPolarHBondContact O-CB 3.43Å; S76-S80 PolarHBondContact O-N 2.92Å; F77-S80 PolarHBondContact O-N 2.91Å; S80-G83 PolarHBondContact O-N 3.5Å; S80-F84 WeakPolarHBondContact O-CD2 3.38Å; S80-F84 PolarHBondContact O-N 3.06Å
81	L	93.8	Very high	89.1	Confident	12 Å²	12	62.5 Å²	62.5	6%	0.063	36%	0.359	C	S	.	.	H	α-helix	trans	-68.9	-41.1	-174.8	-152.2	68.4	0	0	0	111.7	F77 G83 F84 L85 L140 L386 V390	F77-L81 HydrophobicContact CE1-CD2 4.01Å; F77-L81 HydrophobicContact CZ-CD2 4.02Å; F77-L81 VanDerWaalsContact O-CB 3.31Å; F77-L81 WeakPolarHBondContact O-CB 3.46Å; F77-L81 PolarHBondContact O-N 3.35Å; L81-G83 VanDerWaalsContact C-N 3.32Å; L81-G83 PolarHBondContact O-N 3.08Å; L81-F84 PolarHBondContact O-N 3.27Å; L81-L85 VanDerWaalsContact O-CG 3.32Å; L81-L85 WeakPolarHBondContact O-CG 3.2Å; L81-L85 PolarHBondContact O-N 2.85Å; L81-L140 HydrophobicContact CB-CD1 4.16Å; L81-L140 HydrophobicContact CD2-CD1 3.78Å; L81-L140 HydrophobicContact CD2-CD2 3.85Å; L81-L140 HydrophobicContact CD2-CG 4.48Å; L81-L140 HydrophobicContact CG-CD1 4.09Å; L81-L386 HydrophobicContact CD2-CB 3.85Å; L81-V390 HydrophobicContact CD1-CB 4.11Å; L81-V390 HydrophobicContact CD1-CG1 4.44Å; L81-V390 HydrophobicContact CD1-CG2 3.47Å; L81-V390 VanDerWaalsContact CD1-CG2 3.47Å; L81-V390 HydrophobicContact CD2-CG2 3.97Å; L81-V390 HydrophobicContact CG-CG2 3.54Å
82	T	94.4	Very high	91	Very high	22 Å²	22	59 Å²	59	14%	0.135	34%	0.341	C	S	.	.	H	α-helix	trans	-61.2	-42	172.6	-56.8	0	0	0	0	111.1	Q78 F84 L85 M86 I137 L141	Q78-T82 WeakPolarHBondContact O-CB 3.24Å; Q78-T82 PolarHBondContact O-N 2.94Å; Q78-T82 PolarHBondContact O-OG1 3.35Å; T82-F84 PolarHBondContact O-N 3.42Å; T82-L85 PolarHBondContact O-N 3.47Å; T82-M86 HydrophobicContact CG2-CG 4.32Å; T82-M86 WeakPolarHBondContact O-CB 3.34Å; T82-M86 VanDerWaalsContact O-CG 3.28Å; T82-M86 WeakPolarHBondContact O-CG 3.06Å; T82-M86 PolarHBondContact O-N 2.85Å; T82-I137 HydrophobicContact CG2-CG1 4.49Å; T82-I137 HydrophobicContact CG2-CG2 3.84Å; T82-L141 HydrophobicContact CG2-CD2 4.43Å
83	G	96.1	Very high	92.5	Very high	43 Å²	43	57.6 Å²	57.6	44%	0.443	33%	0.327	S	S	.	.	H	α-helix	trans	-59.2	-44.3	175.8	0	0	0	0	0	113	V79 S80 L81 M86 L87	V79-G83 PolarHBondContact O-N 2.83Å; S80-G83 PolarHBondContact O-N 3.5Å; L81-G83 VanDerWaalsContact C-N 3.32Å; L81-G83 PolarHBondContact O-N 3.08Å; G83-M86 PolarHBondContact O-N 2.87Å; G83-L87 PolarHBondContact O-N 2.93Å
84	F	96.6	Very high	93.4	Very high	115 Å²	115	58.1 Å²	58.1	50%	0.504	34%	0.34	S	S	.	.	H	α-helix	trans	-63.9	-44.5	174.6	-78.2	-66.9	0	0	0	112.4	S80 L81 T82 M86 L87 E88 V390	S80-F84 WeakPolarHBondContact O-CD2 3.38Å; S80-F84 PolarHBondContact O-N 3.06Å; L81-F84 PolarHBondContact O-N 3.27Å; T82-F84 PolarHBondContact O-N 3.42Å; F84-M86 VanDerWaalsContact C-N 3.34Å; F84-M86 PolarHBondContact O-N 3.38Å; F84-L87 WeakPolarHBondContact O-CB 3.45Å; F84-L87 PolarHBondContact O-N 3.27Å; F84-L87 VanDerWaalsContact O-N 3.17Å; F84-E88 WeakPolarHBondContact O-CG 3.38Å; F84-E88 PolarHBondContact O-N 2.86Å; F84-V390 HydrophobicContact CB-CG1 4.04Å
85	L	96.5	Very high	93.7	Very high	0 Å²	0	56.2 Å²	56.2	0%	0	33%	0.328	C	S	.	.	H	α-helix	trans	-63.7	-39	178.5	-70.2	166.1	0	0	0	112.1	L81 T82 L87 E88 I89 I133 T136 I137 L140 V390 Y393	L81-L85 VanDerWaalsContact O-CG 3.32Å; L81-L85 WeakPolarHBondContact O-CG 3.2Å; L81-L85 PolarHBondContact O-N 2.85Å; T82-L85 PolarHBondContact O-N 3.47Å; L85-L87 VanDerWaalsContact C-N 3.34Å; L85-L87 PolarHBondContact O-N 3.46Å; L85-E88 WeakPolarHBondContact O-CB 3.25Å; L85-E88 PolarHBondContact O-N 3.43Å; L85-I89 WeakPolarHBondContact O-CG1 3.17Å; L85-I89 PolarHBondContact O-N 3.32Å; L85-I133 HydrophobicContact CB-CG2 3.79Å; L85-I133 HydrophobicContact CD2-CG2 3.74Å; L85-I133 HydrophobicContact CG-CG2 4.33Å; L85-T136 HydrophobicContact CD1-CG2 4.01Å; L85-I137 HydrophobicContact CB-CD1 3.84Å; L85-I137 HydrophobicContact CB-CG1 3.73Å; L85-I137 HydrophobicContact CD1-CG1 3.85Å; L85-I137 HydrophobicContact CG-CG1 4.42Å; L85-L140 HydrophobicContact CD1-CD1 3.47Å; L85-L140 VanDerWaalsContact CD1-CD1 3.47Å; L85-V390 HydrophobicContact CD1-CG2 4.09Å; L85-V390 HydrophobicContact CD2-CB 4.25Å; L85-V390 HydrophobicContact CD2-CG1 4.04Å; L85-V390 HydrophobicContact CD2-CG2 3.7Å; L85-V390 HydrophobicContact CG-CG1 4.28Å; L85-V390 HydrophobicContact CG-CG2 3.88Å; L85-Y393 HydrophobicContact CD2-CD2 3.84Å; L85-Y393 HydrophobicContact CD2-CE2 4.43Å
86	M	96.7	Very high	94.1	Very high	98 Å²	98	50 Å²	50	48%	0.483	30%	0.296	S	S	.	.	H	α-helix	trans	-64	-40	173.6	-71.4	-61	-71	0	0	111.9	T82 G83 F84 E88 I89 V90 I137	T82-M86 HydrophobicContact CG2-CG 4.32Å; T82-M86 WeakPolarHBondContact O-CB 3.34Å; T82-M86 VanDerWaalsContact O-CG 3.28Å; T82-M86 WeakPolarHBondContact O-CG 3.06Å; T82-M86 PolarHBondContact O-N 2.85Å; G83-M86 PolarHBondContact O-N 2.87Å; F84-M86 VanDerWaalsContact C-N 3.34Å; F84-M86 PolarHBondContact O-N 3.38Å; M86-E88 VanDerWaalsContact C-N 3.3Å; M86-E88 PolarHBondContact O-N 3.47Å; M86-I89 PolarHBondContact O-N 3.33Å; M86-I89 HydrophobicContact SD-CD1 4.06Å; M86-V90 WeakPolarHBondContact O-CG2 3.28Å; M86-V90 PolarHBondContact O-N 2.93Å; M86-I137 HydrophobicContact CG-CD1 4.04Å; M86-I137 HydrophobicContact SD-CD1 3.57Å; M86-I137 VanDerWaalsContact SD-CD1 3.57Å
87	L	96.3	Very high	94.3	Very high	88 Å²	88	49.6 Å²	49.6	46%	0.461	29%	0.285	S	S	.	.	H	α-helix	trans	-62.8	-39.2	173.6	-177	66.5	0	0	0	111.4	G83 F84 L85 V90 L91	G83-L87 PolarHBondContact O-N 2.93Å; F84-L87 WeakPolarHBondContact O-CB 3.45Å; F84-L87 PolarHBondContact O-N 3.27Å; F84-L87 VanDerWaalsContact O-N 3.17Å; L85-L87 VanDerWaalsContact C-N 3.34Å; L85-L87 PolarHBondContact O-N 3.46Å; L87-V90 PolarHBondContact O-N 3.34Å; L87-L91 HydrophobicContact CD1-CD1 3.74Å; L87-L91 HydrophobicContact CD1-CG 3.84Å; L87-L91 HydrophobicContact CD2-CD1 4.27Å; L87-L91 HydrophobicContact CG-CD1 3.75Å; L87-L91 HydrophobicContact CG-CG 4.15Å; L87-L91 WeakPolarHBondContact O-CB 3.25Å; L87-L91 WeakPolarHBondContact O-CG 3.23Å; L87-L91 PolarHBondContact O-N 2.86Å
88	E	95.6	Very high	94.3	Very high	16 Å²	16	51.8 Å²	51.8	8%	0.075	30%	0.302	C	S	.	.	H	α-helix	trans	-63.2	-40.5	174.6	-71.6	179.8	-179	0	0	112.8	F84 L85 M86 G92 I133 Y393 G394 I397	F84-E88 WeakPolarHBondContact O-CG 3.38Å; F84-E88 PolarHBondContact O-N 2.86Å; L85-E88 WeakPolarHBondContact O-CB 3.25Å; L85-E88 PolarHBondContact O-N 3.43Å; M86-E88 VanDerWaalsContact C-N 3.3Å; M86-E88 PolarHBondContact O-N 3.47Å; E88-G92 WeakPolarHBondContact O-CA 3.23Å; E88-G92 PolarHBondContact O-N 3.05Å; E88-I133 HydrophobicContact CB-CD1 3.93Å; E88-Y393 WeakPolarHBondContact OE2-CB 3.47Å; E88-G394 PolarHBondContact OE1-N 3.48Å; E88-I397 HydrophobicContact CB-CD1 4.24Å; E88-I397 HydrophobicContact CG-CD1 3.66Å; E88-I397 HydrophobicContact CG-CG1 4.44Å
89	I	96.8	Very high	94.2	Very high	32 Å²	32	51.1 Å²	51.1	16%	0.164	30%	0.301	C	S	.	.	H	α-helix	trans	-59.7	-52.3	172.6	-66.5	168.4	0	0	0	109.8	L85 M86 L93 I133 P134 I137	L85-I89 WeakPolarHBondContact O-CG1 3.17Å; L85-I89 PolarHBondContact O-N 3.32Å; M86-I89 PolarHBondContact O-N 3.33Å; M86-I89 HydrophobicContact SD-CD1 4.06Å; I89-L93 WeakPolarHBondContact O-CA 3.29Å; I89-L93 WeakPolarHBondContact O-CB 3.38Å; I89-L93 PolarHBondContact O-N 2.88Å; I89-I133 HydrophobicContact CD1-CB 4.44Å; I89-I133 HydrophobicContact CD1-CG2 3.83Å; I89-I133 HydrophobicContact CG1-CB 4.07Å; I89-I133 HydrophobicContact CG1-CG2 3.59Å; I89-P134 HydrophobicContact CD1-CG 3.99Å; I89-I137 HydrophobicContact CD1-CD1 3.86Å
90	V	96.3	Very high	94	Very high	101 Å²	101	48.5 Å²	48.5	61%	0.612	28%	0.283	S	S	*	.	H	α-helix	trans	-63.4	-50.7	-175.3	174	0	0	0	0	111.5	M86 L87 G94	M86-V90 WeakPolarHBondContact O-CG2 3.28Å; M86-V90 PolarHBondContact O-N 2.93Å; L87-V90 PolarHBondContact O-N 3.34Å; V90-G94 PolarHBondContact O-N 3.42Å; V90-G94 VanDerWaalsContact O-N 3.1Å
91	L	95	Very high	93.7	Very high	76 Å²	76	48.8 Å²	48.8	40%	0.398	28%	0.282	S	S	.	.	H	α-helix	trans	-73.3	-43.6	-177.6	-65.4	-176.8	0	0	0	112.1	L87 S95 I397	L87-L91 HydrophobicContact CD1-CD1 3.74Å; L87-L91 HydrophobicContact CD1-CG 3.84Å; L87-L91 HydrophobicContact CD2-CD1 4.27Å; L87-L91 HydrophobicContact CG-CD1 3.75Å; L87-L91 HydrophobicContact CG-CG 4.15Å; L87-L91 WeakPolarHBondContact O-CB 3.25Å; L87-L91 WeakPolarHBondContact O-CG 3.23Å; L87-L91 PolarHBondContact O-N 2.86Å; L91-S95 WeakPolarHBondContact O-CB 3.42Å; L91-S95 PolarHBondContact O-N 3.13Å; L91-S95 PolarHBondContact O-OG 3.24Å; L91-I397 HydrophobicContact CB-CD1 4.16Å; L91-I397 HydrophobicContact CB-CG1 3.94Å; L91-I397 HydrophobicContact CB-CG2 4.07Å; L91-I397 HydrophobicContact CD1-CD1 4.24Å; L91-I397 HydrophobicContact CD1-CG2 4.42Å
92	G	94.7	Very high	93.2	Very high	0 Å²	0	53 Å²	53	0%	0	30%	0.304	C	S	.	.	H	α-helix	trans	-64.7	-54	179.8	0	0	0	0	0	111.1	E88 S95 N96	E88-G92 WeakPolarHBondContact O-CA 3.23Å; E88-G92 PolarHBondContact O-N 3.05Å; G92-S95 PolarHBondContact O-OG 3.34Å; G92-N96 WeakPolarHBondContact O-CB 3.27Å; G92-N96 PolarHBondContact O-N 2.99Å; G92-N96 PolarHBondContact O-ND2 2.86Å
93	L	94.3	Very high	92.7	Very high	56 Å²	56	53.2 Å²	53.2	29%	0.293	30%	0.303	S	S	.	.	H	α-helix	trans	-63	-48.7	179.8	-167.4	70	0	0	0	111.3	I89 S95 L97 V126 C129 V130	I89-L93 WeakPolarHBondContact O-CA 3.29Å; I89-L93 WeakPolarHBondContact O-CB 3.38Å; I89-L93 PolarHBondContact O-N 2.88Å; L93-S95 PolarHBondContact O-N 2.9Å; L93-L97 WeakPolarHBondContact O-CB 3.43Å; L93-L97 PolarHBondContact O-N 2.84Å; L93-V126 HydrophobicContact CD1-CG1 3.89Å; L93-V126 HydrophobicContact CD1-CG2 4.35Å; L93-C129 HydrophobicContact CB-CB 4.43Å; L93-C129 HydrophobicContact CD1-CB 4.39Å; L93-V130 HydrophobicContact CD1-CG1 3.67Å
94	G	92.2	Very high	92.1	Very high	36 Å²	36	55.5 Å²	55.5	37%	0.371	31%	0.311	S	S	.	.	H	α-helix	trans	-59.9	-46.1	-178.4	0	0	0	0	0	112.6	V90 T98	V90-G94 PolarHBondContact O-N 3.42Å; V90-G94 VanDerWaalsContact O-N 3.1Å; G94-T98 WeakPolarHBondContact O-CB 3.3Å; G94-T98 PolarHBondContact O-N 2.83Å; G94-T98 VanDerWaalsContact O-N 3.12Å; G94-T98 PolarHBondContact O-OG1 3.15Å
95	S	91.8	Very high	91.3	Very high	26 Å²	26	57.3 Å²	57.3	18%	0.182	32%	0.323	C	S	.	.	H	α-helix	trans	-73.2	-41.6	-177.8	66.9	0	0	0	0	113.2	L91 G92 L93 V99 P400	L91-S95 WeakPolarHBondContact O-CB 3.42Å; L91-S95 PolarHBondContact O-N 3.13Å; L91-S95 PolarHBondContact O-OG 3.24Å; G92-S95 PolarHBondContact O-OG 3.34Å; L93-S95 PolarHBondContact O-N 2.9Å; S95-V99 WeakPolarHBondContact O-CG2 3.49Å; S95-V99 PolarHBondContact O-N 3.35Å; S95-P400 WeakPolarHBondContact OG-CG 3.22Å
96	N	93.4	Very high	90.4	Very high	0 Å²	0	63 Å²	63	0%	0	35%	0.348	C	S	.	.	H	α-helix	trans	-69.5	-42.3	178.4	-74.6	-70.4	0	0	0	112.2	G92 T98 V99 L100 H122 D125 V126 T396 P400	G92-N96 WeakPolarHBondContact O-CB 3.27Å; G92-N96 PolarHBondContact O-N 2.99Å; G92-N96 PolarHBondContact O-ND2 2.86Å; N96-T98 VanDerWaalsContact C-N 3.34Å; N96-T98 PolarHBondContact O-N 2.87Å; N96-V99 PolarHBondContact O-N 3.34Å; N96-L100 PolarHBondContact O-N 2.92Å; N96-H122 HydrophobicContact CB-CB 4.49Å; N96-H122 PolarHBondContact OD1-ND1 2.87Å; N96-D125 HydrophobicContact CB-CB 4.45Å; N96-D125 PolarHBondContact OD1-OD2 3.18Å; N96-V126 HydrophobicContact CB-CG2 3.75Å; N96-T396 PolarHBondContact ND2-O 3.5Å; N96-P400 HydrophobicContact CB-CG 4.28Å; N96-P400 WeakPolarHBondContact OD1-CD 3.39Å; N96-P400 WeakPolarHBondContact OD1-CG 3.28Å
97	L	92.8	Very high	89.1	Confident	85 Å²	85	62 Å²	62	45%	0.445	35%	0.351	S	S	.	.	H	α-helix	trans	-63.5	-41.5	176.9	-174.3	61.7	0	0	0	111.4	L93 V99 L100 V101	L93-L97 WeakPolarHBondContact O-CB 3.43Å; L93-L97 PolarHBondContact O-N 2.84Å; L97-V99 VanDerWaalsContact C-N 3.28Å; L97-V99 PolarHBondContact O-N 3.21Å; L97-L100 PolarHBondContact O-N 3.1Å; L97-L100 VanDerWaalsContact O-N 3.16Å; L97-V101 HydrophobicContact CD1-CG2 4.4Å; L97-V101 HydrophobicContact CG-CG2 4.39Å; L97-V101 WeakPolarHBondContact O-CG2 3.26Å; L97-V101 PolarHBondContact O-N 3.4Å
98	T	89.4	Confident	88	Confident	85 Å²	85	63.7 Å²	63.7	52%	0.521	36%	0.36	S	S	.	.	H	α-helix	trans	-56.3	-44.4	174.7	-62.6	0	0	0	0	111.2	G94 N96 L102	G94-T98 WeakPolarHBondContact O-CB 3.3Å; G94-T98 PolarHBondContact O-N 2.83Å; G94-T98 VanDerWaalsContact O-N 3.12Å; G94-T98 PolarHBondContact O-OG1 3.15Å; N96-T98 VanDerWaalsContact C-N 3.34Å; N96-T98 PolarHBondContact O-N 2.87Å; T98-L102 HydrophobicContact CG2-CD1 4.43Å; T98-L102 VanDerWaalsContact O-CG 3.28Å; T98-L102 WeakPolarHBondContact O-CG 3.3Å; T98-L102 PolarHBondContact O-N 3.49Å; T98-L102 VanDerWaalsContact O-N 3.13Å
99	V	87.9	Confident	86.8	Confident	26 Å²	26	65 Å²	65	16%	0.158	37%	0.367	C	S	.	.	H	α-helix	trans	-66.1	-42.9	178	175.9	0	0	0	0	111.2	S95 N96 L97 L102 Y103 H122 P400	S95-V99 WeakPolarHBondContact O-CG2 3.49Å; S95-V99 PolarHBondContact O-N 3.35Å; N96-V99 PolarHBondContact O-N 3.34Å; L97-V99 VanDerWaalsContact C-N 3.28Å; L97-V99 PolarHBondContact O-N 3.21Å; V99-L102 WeakPolarHBondContact O-CB 3.39Å; V99-L102 PolarHBondContact O-N 3.43Å; V99-Y103 HydrophobicContact CG1-CD2 3.8Å; V99-Y103 HydrophobicContact CG1-CE2 3.49Å; V99-Y103 VanDerWaalsContact CG1-CE2 3.49Å; V99-Y103 WeakPolarHBondContact O-CD2 3.47Å; V99-Y103 PolarHBondContact O-N 3.42Å; V99-Y103 VanDerWaalsContact O-N 3.14Å; V99-H122 VanDerWaalsContact CG1-CD2 3.48Å; V99-H122 WeakPolarHBondContact CG1-CD2 3.16Å; V99-H122 WeakPolarHBondContact CG1-NE2 3.35Å; V99-P400 HydrophobicContact CG2-CB 4.21Å
100	L	89.4	Confident	85.5	Confident	40 Å²	40	66.4 Å²	66.4	21%	0.209	38%	0.375	C	S	.	.	H	α-helix	trans	-61.6	-45.8	178.3	-173.3	61.7	0	0	0	111.9	N96 L97 L102 Y103 C104 M119 V123	N96-L100 PolarHBondContact O-N 2.92Å; L97-L100 PolarHBondContact O-N 3.1Å; L97-L100 VanDerWaalsContact O-N 3.16Å; L100-L102 VanDerWaalsContact C-N 3.3Å; L100-L102 PolarHBondContact O-N 3.15Å; L100-Y103 WeakPolarHBondContact O-CB 3.47Å; L100-Y103 PolarHBondContact O-N 3Å; L100-C104 PolarHBondContact O-N 2.84Å; L100-C104 PolarHBondContact O-SG 3.39Å; L100-C104 VanDerWaalsContact O-SG 3.37Å; L100-M119 HydrophobicContact CD1-CG 3.74Å; L100-M119 HydrophobicContact CD1-SD 4.25Å; L100-V123 HydrophobicContact CD1-CG2 4.23Å
101	V	87.6	Confident	84.5	Confident	67 Å²	67	67.4 Å²	67.4	41%	0.406	38%	0.376	S	S	.	.	H	α-helix	trans	-57.4	-43.1	175	170.1	0	0	0	0	111	L97 Y103 C104 M105	L97-V101 HydrophobicContact CD1-CG2 4.4Å; L97-V101 HydrophobicContact CG-CG2 4.39Å; L97-V101 WeakPolarHBondContact O-CG2 3.26Å; L97-V101 PolarHBondContact O-N 3.4Å; V101-Y103 VanDerWaalsContact C-N 3.27Å; V101-Y103 PolarHBondContact O-N 3.21Å; V101-C104 PolarHBondContact O-N 3.29Å; V101-M105 HydrophobicContact CG1-CG 4.13Å; V101-M105 HydrophobicContact CG1-SD 3.75Å; V101-M105 WeakPolarHBondContact O-CB 3.37Å; V101-M105 VanDerWaalsContact O-CG 3.27Å; V101-M105 WeakPolarHBondContact O-CG 3.45Å; V101-M105 PolarHBondContact O-N 3.34Å
102	L	84.4	Confident	84	Confident	101 Å²	101	66 Å²	66	53%	0.529	37%	0.373	S	S	.	.	H	α-helix	trans	-62.8	-31.3	176.6	-71.2	172.7	0	0	0	113.4	T98 V99 L100	T98-L102 HydrophobicContact CG2-CD1 4.43Å; T98-L102 VanDerWaalsContact O-CG 3.28Å; T98-L102 WeakPolarHBondContact O-CG 3.3Å; T98-L102 PolarHBondContact O-N 3.49Å; T98-L102 VanDerWaalsContact O-N 3.13Å; V99-L102 WeakPolarHBondContact O-CB 3.39Å; V99-L102 PolarHBondContact O-N 3.43Å; L100-L102 VanDerWaalsContact C-N 3.3Å; L100-L102 PolarHBondContact O-N 3.15Å
103	Y	83.4	Confident	83.6	Confident	26 Å²	26	66.5 Å²	66.5	10%	0.102	38%	0.376	C	S	.	.	H	α-helix	trans	-71.5	-44.5	172.7	-80.9	-73	0	0	0	111.3	V99 L100 V101 M105 K106 L109 N115	V99-Y103 HydrophobicContact CG1-CD2 3.8Å; V99-Y103 HydrophobicContact CG1-CE2 3.49Å; V99-Y103 VanDerWaalsContact CG1-CE2 3.49Å; V99-Y103 WeakPolarHBondContact O-CD2 3.47Å; V99-Y103 PolarHBondContact O-N 3.42Å; V99-Y103 VanDerWaalsContact O-N 3.14Å; L100-Y103 WeakPolarHBondContact O-CB 3.47Å; L100-Y103 PolarHBondContact O-N 3Å; V101-Y103 VanDerWaalsContact C-N 3.27Å; V101-Y103 PolarHBondContact O-N 3.21Å; Y103-M105 PolarHBondContact O-N 2.89Å; Y103-K106 CarbonylContact O-C 3.42Å; Y103-K106 PolarHBondContact O-N 2.95Å; Y103-L109 HydrophobicContact CD1-CB 3.68Å; Y103-L109 HydrophobicContact CD1-CD1 4.09Å; Y103-L109 HydrophobicContact CD1-CG 4.47Å; Y103-L109 HydrophobicContact CE1-CB 3.97Å; Y103-L109 HydrophobicContact CE1-CD1 4.37Å; Y103-N115 HydrophobicContact CE1-CB 4Å
104	C	83	Confident	83.2	Confident	92 Å²	92	64.3 Å²	64.3	62%	0.622	37%	0.365	S	S	*	.	H	α-helix	trans	-62.3	-42.8	177.9	-63.8	0	0	0	0	112.4	L100 V101 K106	L100-C104 PolarHBondContact O-N 2.84Å; L100-C104 PolarHBondContact O-SG 3.39Å; L100-C104 VanDerWaalsContact O-SG 3.37Å; V101-C104 PolarHBondContact O-N 3.29Å; C104-K106 PolarHBondContact O-N 2.82Å; C104-K106 VanDerWaalsContact O-N 3.17Å
105	M	79.8	Confident	82.9	Confident	152 Å²	152	64.7 Å²	64.7	75%	0.749	36%	0.359	S	S	*	.	T	Hydrogen-bonded Turn	trans	-66.5	-16.6	179.3	-69.8	178	79.4	0	0	113.5	V101 Y103	V101-M105 HydrophobicContact CG1-CG 4.13Å; V101-M105 HydrophobicContact CG1-SD 3.75Å; V101-M105 WeakPolarHBondContact O-CB 3.37Å; V101-M105 VanDerWaalsContact O-CG 3.27Å; V101-M105 WeakPolarHBondContact O-CG 3.45Å; V101-M105 PolarHBondContact O-N 3.34Å; Y103-M105 PolarHBondContact O-N 2.89Å
106	K	78.6	Confident	82.8	Confident	120 Å²	120	65 Å²	65	52%	0.522	36%	0.358	S	S	.	.			trans	-133.6	82.6	-173.8	-170.7	167.7	-174.4	159.6	0	111	Y103 C104 N108 L109	Y103-K106 CarbonylContact O-C 3.42Å; Y103-K106 PolarHBondContact O-N 2.95Å; C104-K106 PolarHBondContact O-N 2.82Å; C104-K106 VanDerWaalsContact O-N 3.17Å; K106-N108 PolarHBondContact O-N 3.21Å; K106-L109 HydrophobicContact CB-CD1 3.8Å; K106-L109 HydrophobicContact CB-CG 4.22Å; K106-L109 HydrophobicContact CD-CD1 3.92Å; K106-L109 HydrophobicContact CD-CG 4.06Å; K106-L109 HydrophobicContact CG-CD1 4Å; K106-L109 HydrophobicContact CG-CG 3.97Å; K106-L109 WeakPolarHBondContact O-CB 3.31Å; K106-L109 PolarHBondContact O-N 2.82Å
107	S	68.6	Low	82.6	Confident	78 Å²	78	65 Å²	65	55%	0.545	36%	0.358	S	S	.	.	G	3₁₀ helix	trans	-45.7	-37.5	178.5	59.6	0	0	0	0	114.5	L109 I110	S107-L109 PolarHBondContact O-N 3.43Å; S107-I110 WeakPolarHBondContact O-CG1 3.48Å; S107-I110 PolarHBondContact O-N 2.96Å; S107-I110 VanDerWaalsContact O-N 3.09Å
108	N	72.3	Confident	82.3	Confident	122 Å²	122	61.1 Å²	61.1	65%	0.652	34%	0.338	S	S	*	.	G	3₁₀ helix	trans	-60.3	-17.6	177	-71.5	-62.3	0	0	0	114.9	K106	K106-N108 PolarHBondContact O-N 3.21Å
109	L	71.4	Confident	82.3	Confident	45 Å²	45	59.2 Å²	59.2	24%	0.236	32%	0.324	C	S	.	.	G	3₁₀ helix	trans	-79.5	-23.2	176.9	-70.8	169.2	0	0	0	112.6	Y103 K106 S107 N111 N115	Y103-L109 HydrophobicContact CD1-CB 3.68Å; Y103-L109 HydrophobicContact CD1-CD1 4.09Å; Y103-L109 HydrophobicContact CD1-CG 4.47Å; Y103-L109 HydrophobicContact CE1-CB 3.97Å; Y103-L109 HydrophobicContact CE1-CD1 4.37Å; K106-L109 HydrophobicContact CB-CD1 3.8Å; K106-L109 HydrophobicContact CB-CG 4.22Å; K106-L109 HydrophobicContact CD-CD1 3.92Å; K106-L109 HydrophobicContact CD-CG 4.06Å; K106-L109 HydrophobicContact CG-CD1 4Å; K106-L109 HydrophobicContact CG-CG 3.97Å; K106-L109 WeakPolarHBondContact O-CB 3.31Å; K106-L109 PolarHBondContact O-N 2.82Å; S107-L109 PolarHBondContact O-N 3.43Å; L109-N111 VanDerWaalsContact C-N 3.32Å; L109-N111 PolarHBondContact O-N 3.38Å; L109-N115 WeakPolarHBondContact O-CB 3.13Å; L109-N115 PolarHBondContact O-ND2 3.23Å
110	I	70.2	Confident	82.5	Confident	61 Å²	61	58.9 Å²	58.9	31%	0.313	32%	0.321	S	S	.	.	T	Hydrogen-bonded Turn	trans	-83.5	-15	-171.1	-33	168.6	0	0	0	111.5	S107 S112 I116	S107-I110 WeakPolarHBondContact O-CG1 3.48Å; S107-I110 PolarHBondContact O-N 2.96Å; S107-I110 VanDerWaalsContact O-N 3.09Å; I110-S112 PolarHBondContact O-N 2.94Å; I110-I116 HydrophobicContact CG2-CD1 4.38Å; I110-I116 HydrophobicContact CG2-CG1 4.05Å; I110-I116 WeakPolarHBondContact O-CG1 3.26Å
111	N	74.5	Confident	82.6	Confident	121 Å²	121	57 Å²	57	65%	0.647	31%	0.311	S	S	*	.	T	Hydrogen-bonded Turn	trans	-70.2	-2.4	-175.9	-63.5	-22.7	0	0	0	115.1	L109	L109-N111 VanDerWaalsContact C-N 3.32Å; L109-N111 PolarHBondContact O-N 3.38Å
112	S	84.5	Confident	82.9	Confident	46 Å²	46	53.8 Å²	53.8	32%	0.322	29%	0.292	S	S	.	.	S	Bend	trans	-113.1	129.6	-178.4	177.8	0	0	0	0	110.9	I110 S114 N115 I116	I110-S112 PolarHBondContact O-N 2.94Å; S112-S114 VanDerWaalsContact C-N 3.26Å; S112-S114 PolarHBondContact O-N 3.03Å; S112-N115 WeakPolarHBondContact O-CA 3.42Å; S112-N115 WeakPolarHBondContact O-CB 3.4Å; S112-N115 PolarHBondContact O-N 3.41Å; S112-I116 PolarHBondContact O-N 3.31Å; S112-I116 VanDerWaalsContact O-N 3.16Å
113	V	86.9	Confident	83.4	Confident	12 Å²	12	51.2 Å²	51.2	7%	0.073	28%	0.28	C	S	.	.	H	α-helix	trans	-44.3	-50.4	173.9	170.9	0	0	0	0	112.3	N115 I116 I117 L189 M191 A194	V113-N115 PolarHBondContact O-N 3.4Å; V113-I116 PolarHBondContact O-N 3.33Å; V113-I117 HydrophobicContact CG1-CD1 3.76Å; V113-I117 WeakPolarHBondContact O-CG1 3.44Å; V113-I117 PolarHBondContact O-N 3.41Å; V113-L189 HydrophobicContact CG1-CD2 3.72Å; V113-L189 HydrophobicContact CG1-CG 3.83Å; V113-M191 HydrophobicContact CG2-CB 4.4Å; V113-M191 HydrophobicContact CG2-SD 4.03Å; V113-A194 HydrophobicContact CB-CB 4.47Å; V113-A194 HydrophobicContact CG1-CB 3.64Å; V113-A194 HydrophobicContact CG2-CB 4.3Å
114	S	86.1	Confident	84	Confident	10 Å²	10	50 Å²	50	7%	0.07	28%	0.275	C	S	.	.	H	α-helix	trans	-60.5	-29.4	-179.8	-46.8	0	0	0	0	114.2	S112 T118 D176 I180	S112-S114 VanDerWaalsContact C-N 3.26Å; S112-S114 PolarHBondContact O-N 3.03Å; S114-T118 WeakPolarHBondContact O-CB 3.49Å; S114-T118 PolarHBondContact O-N 3.28Å; S114-T118 PolarHBondContact O-OG1 3.04Å; S114-D176 WeakPolarHBondContact CA-OD2 3.32Å; S114-D176 WeakPolarHBondContact CB-OD2 3.43Å; S114-D176 PolarHBondContact OG-OD1 2.64Å; S114-D176 PolarHBondContact OG-OD2 2.84Å; S114-I180 VanDerWaalsContact OG-CD1 3.31Å; S114-I180 WeakPolarHBondContact OG-CD1 3.23Å
115	N	85.9	Confident	84.6	Confident	44 Å²	44	45.6 Å²	45.6	24%	0.235	25%	0.246	C	C	.	.	H	α-helix	trans	-81.2	-36.8	-179.3	-68.5	-7.6	0	0	0	110.6	Y103 L109 S112 V113 T118 M119	Y103-N115 HydrophobicContact CE1-CB 4Å; L109-N115 WeakPolarHBondContact O-CB 3.13Å; L109-N115 PolarHBondContact O-ND2 3.23Å; S112-N115 WeakPolarHBondContact O-CA 3.42Å; S112-N115 WeakPolarHBondContact O-CB 3.4Å; S112-N115 PolarHBondContact O-N 3.41Å; V113-N115 PolarHBondContact O-N 3.4Å; N115-T118 PolarHBondContact O-N 2.98Å; N115-M119 VanDerWaalsContact O-CB 3.25Å; N115-M119 WeakPolarHBondContact O-CB 3.37Å; N115-M119 PolarHBondContact O-N 3.03Å
116	I	88.3	Confident	85.4	Confident	31 Å²	31	39.8 Å²	39.8	16%	0.159	22%	0.218	C	C	.	.	H	α-helix	trans	-63.9	-46.8	172.8	-63.3	-172.7	0	0	0	110.9	I110 S112 V113 T118 M119 N120 M191	I110-I116 HydrophobicContact CG2-CD1 4.38Å; I110-I116 HydrophobicContact CG2-CG1 4.05Å; I110-I116 WeakPolarHBondContact O-CG1 3.26Å; S112-I116 PolarHBondContact O-N 3.31Å; S112-I116 VanDerWaalsContact O-N 3.16Å; V113-I116 PolarHBondContact O-N 3.33Å; I116-T118 VanDerWaalsContact C-N 3.29Å; I116-T118 PolarHBondContact O-N 3.28Å; I116-M119 WeakPolarHBondContact O-CB 3.09Å; I116-M119 PolarHBondContact O-N 3.34Å; I116-M119 VanDerWaalsContact O-N 3.14Å; I116-N120 PolarHBondContact O-N 2.79Å; I116-M191 HydrophobicContact CD1-CE 3.61Å; I116-M191 HydrophobicContact CD1-SD 3.42Å; I116-M191 WeakPolarHBondContact CD1-SD 3.5Å; I116-M191 HydrophobicContact CG1-CE 4.47Å; I116-M191 HydrophobicContact CG1-SD 4.49Å
117	I	89.8	Confident	86.3	Confident	1 Å²	1	37.4 Å²	37.4	1%	0.005	21%	0.211	C	C	.	.	H	α-helix	trans	-60.3	-42.2	178	-66.1	168.2	0	0	0	110.7	V113 N120 L121 A172 I173 D176 L189 M198	V113-I117 HydrophobicContact CG1-CD1 3.76Å; V113-I117 WeakPolarHBondContact O-CG1 3.44Å; V113-I117 PolarHBondContact O-N 3.41Å; I117-N120 PolarHBondContact O-N 3Å; I117-L121 PolarHBondContact O-N 3.45Å; I117-A172 HydrophobicContact CG2-CB 4.07Å; I117-I173 HydrophobicContact CG2-CB 4.48Å; I117-I173 HydrophobicContact CG2-CG1 3.65Å; I117-D176 HydrophobicContact CD1-CB 3.81Å; I117-L189 HydrophobicContact CD1-CD2 3.69Å; I117-M198 HydrophobicContact CG1-SD 4.03Å
118	T	87.1	Confident	87.6	Confident	3 Å²	3	33.8 Å²	33.8	2%	0.018	19%	0.186	C	C	.	.	H	α-helix	trans	-65.4	-42.1	174.9	-66.1	0	0	0	0	112.2	S114 N115 I116 N120 L121 H122 Y403	S114-T118 WeakPolarHBondContact O-CB 3.49Å; S114-T118 PolarHBondContact O-N 3.28Å; S114-T118 PolarHBondContact O-OG1 3.04Å; N115-T118 PolarHBondContact O-N 2.98Å; I116-T118 VanDerWaalsContact C-N 3.29Å; I116-T118 PolarHBondContact O-N 3.28Å; T118-N120 VanDerWaalsContact C-N 3.29Å; T118-N120 PolarHBondContact O-N 3.32Å; T118-L121 WeakPolarHBondContact O-CB 3.22Å; T118-L121 PolarHBondContact O-N 3.24Å; T118-H122 PolarHBondContact O-CD2 3.36Å; T118-H122 PolarHBondContact O-N 2.84Å; T118-Y403 HydrophobicContact CG2-CD1 3.96Å; T118-Y403 HydrophobicContact CG2-CE1 3.16Å; T118-Y403 HydrophobicContact CG2-CE2 4.37Å; T118-Y403 VanDerWaalsContact CG2-CZ 3.43Å; T118-Y403 WeakPolarHBondContact CG2-OH 3Å; T118-Y403 PolarHBondContact OG1-OH 3.2Å
119	M	88.6	Confident	88.8	Confident	46 Å²	46	28 Å²	28	23%	0.227	16%	0.155	C	C	.	.	H	α-helix	trans	-62.5	-40.3	179	-176.1	-175.9	77.9	0	0	110.7	L100 N115 I116 L121 H122 V123	L100-M119 HydrophobicContact CD1-CG 3.74Å; L100-M119 HydrophobicContact CD1-SD 4.25Å; N115-M119 VanDerWaalsContact O-CB 3.25Å; N115-M119 WeakPolarHBondContact O-CB 3.37Å; N115-M119 PolarHBondContact O-N 3.03Å; I116-M119 WeakPolarHBondContact O-CB 3.09Å; I116-M119 PolarHBondContact O-N 3.34Å; I116-M119 VanDerWaalsContact O-N 3.14Å; M119-L121 VanDerWaalsContact C-N 3.27Å; M119-L121 PolarHBondContact O-N 3.13Å; M119-H122 PolarHBondContact O-N 3.02Å; M119-H122 VanDerWaalsContact O-N 3.1Å; M119-V123 PolarHBondContact O-N 3.34Å
120	N	91.9	Very high	90	Very high	19 Å²	19	29.8 Å²	29.8	10%	0.102	17%	0.167	C	C	.	.	H	α-helix	trans	-61.8	-35.3	176.7	-164.4	81.7	0	0	0	112.8	I116 I117 T118 H122 V123 L124 N169 M198 W202	I116-N120 PolarHBondContact O-N 2.79Å; I117-N120 PolarHBondContact O-N 3Å; T118-N120 VanDerWaalsContact C-N 3.29Å; T118-N120 PolarHBondContact O-N 3.32Å; N120-H122 VanDerWaalsContact C-N 3.33Å; N120-H122 PolarHBondContact O-N 2.9Å; N120-V123 PolarHBondContact O-N 2.83Å; N120-L124 PolarHBondContact O-N 2.9Å; N120-N169 PolarHBondContact ND2-OD1 3.42Å; N120-M198 HydrophobicContact CB-CE 3.37Å; N120-M198 WeakPolarHBondContact ND2-CE 3.4Å; N120-W202 WeakPolarHBondContact OD1-CZ2 3.34Å; N120-W202 PolarHBondContact OD1-NE1 3.43Å
121	L	92.1	Very high	91.1	Very high	0 Å²	0	28.4 Å²	28.4	0%	0	17%	0.168	C	C	.	.	H	α-helix	trans	-59.5	-44.8	173.3	-174.6	72.2	0	0	0	111.1	I117 T118 M119 V123 L124 D125 N169 I173 H399	I117-L121 PolarHBondContact O-N 3.45Å; T118-L121 WeakPolarHBondContact O-CB 3.22Å; T118-L121 PolarHBondContact O-N 3.24Å; M119-L121 VanDerWaalsContact C-N 3.27Å; M119-L121 PolarHBondContact O-N 3.13Å; L121-V123 VanDerWaalsContact C-N 3.31Å; L121-V123 PolarHBondContact O-N 3.18Å; L121-L124 WeakPolarHBondContact O-CB 3.5Å; L121-L124 PolarHBondContact O-N 3.45Å; L121-D125 VanDerWaalsContact O-CG 3.29Å; L121-D125 PolarHBondContact O-N 3.24Å; L121-N169 HydrophobicContact CD1-CB 3.91Å; L121-I173 HydrophobicContact CB-CD1 4.42Å; L121-I173 HydrophobicContact CD2-CD1 3.75Å; L121-I173 HydrophobicContact CG-CD1 4.47Å; L121-H399 HydrophobicContact CD2-CB 4.16Å
122	H	93.2	Very high	92.1	Very high	0 Å²	0	22.8 Å²	22.8	0%	0	14%	0.138	C	C	.	.	H	α-helix	trans	-66	-33.2	177.1	-64.9	-58.1	0	0	0	112.9	N96 V99 T118 M119 N120 V126	N96-H122 HydrophobicContact CB-CB 4.49Å; N96-H122 PolarHBondContact OD1-ND1 2.87Å; V99-H122 VanDerWaalsContact CG1-CD2 3.48Å; V99-H122 WeakPolarHBondContact CG1-CD2 3.16Å; V99-H122 WeakPolarHBondContact CG1-NE2 3.35Å; T118-H122 PolarHBondContact O-CD2 3.36Å; T118-H122 PolarHBondContact O-N 2.84Å; M119-H122 PolarHBondContact O-N 3.02Å; M119-H122 VanDerWaalsContact O-N 3.1Å; N120-H122 VanDerWaalsContact C-N 3.33Å; N120-H122 PolarHBondContact O-N 2.9Å; H122-V126 WeakPolarHBondContact O-CG2 3.4Å; H122-V126 PolarHBondContact O-N 3.45Å; H122-V126 VanDerWaalsContact O-N 3.09Å
123	V	94.9	Very high	92.7	Very high	47 Å²	47	20.6 Å²	20.6	29%	0.285	12%	0.123	S	C	.	.	H	α-helix	trans	-64.6	-45.1	172.7	173.9	0	0	0	0	110.4	L100 M119 N120 L121 V126 L127 W202	L100-V123 HydrophobicContact CD1-CG2 4.23Å; M119-V123 PolarHBondContact O-N 3.34Å; N120-V123 PolarHBondContact O-N 2.83Å; L121-V123 VanDerWaalsContact C-N 3.31Å; L121-V123 PolarHBondContact O-N 3.18Å; V123-V126 PolarHBondContact O-N 3.01Å; V123-L127 WeakPolarHBondContact O-CG 3.46Å; V123-L127 PolarHBondContact O-N 3.47Å; V123-L127 VanDerWaalsContact O-N 3.07Å; V123-W202 HydrophobicContact CG1-CH2 4.22Å; V123-W202 HydrophobicContact CG1-CZ2 4.14Å
124	L	96.3	Very high	93.1	Very high	0 Å²	0	22.2 Å²	22.2	0%	0	13%	0.134	C	C	.	.	H	α-helix	trans	-60.5	-46.8	175.3	174	64	0	0	0	111.8	N120 L121 V126 L127 I128 F161 S165 N169	N120-L124 PolarHBondContact O-N 2.9Å; L121-L124 WeakPolarHBondContact O-CB 3.5Å; L121-L124 PolarHBondContact O-N 3.45Å; L124-V126 VanDerWaalsContact C-N 3.26Å; L124-V126 PolarHBondContact O-N 3.43Å; L124-L127 WeakPolarHBondContact O-CB 3.24Å; L124-L127 PolarHBondContact O-N 3.06Å; L124-L127 VanDerWaalsContact O-N 3.08Å; L124-I128 HydrophobicContact CD1-CD1 4.1Å; L124-I128 HydrophobicContact CD1-CG1 4.23Å; L124-I128 HydrophobicContact CG-CD1 3.98Å; L124-I128 HydrophobicContact CG-CG1 4.49Å; L124-I128 WeakPolarHBondContact O-CG1 3.39Å; L124-I128 PolarHBondContact O-N 3.48Å; L124-F161 HydrophobicContact CD1-CE1 3.81Å; L124-F161 HydrophobicContact CD1-CZ 3.92Å; L124-S165 VanDerWaalsContact CD1-CB 3.43Å; L124-S165 VanDerWaalsContact CD2-C 3.46Å; L124-N169 HydrophobicContact CD2-CB 4.3Å
125	D	95.9	Very high	93.4	Very high	0 Å²	0	22.8 Å²	22.8	0%	0	14%	0.136	C	C	.	.	H	α-helix	trans	-60.3	-37.8	-179.8	-68.9	-24.3	0	0	0	111.3	N96 L121 I128 C129 T396 H399	N96-D125 HydrophobicContact CB-CB 4.45Å; N96-D125 PolarHBondContact OD1-OD2 3.18Å; L121-D125 VanDerWaalsContact O-CG 3.29Å; L121-D125 PolarHBondContact O-N 3.24Å; D125-I128 PolarHBondContact O-N 3.48Å; D125-C129 PolarHBondContact O-N 3.11Å; D125-C129 PolarHBondContact O-SG 3.4Å; D125-T396 HydrophobicContact CB-CG2 4.13Å; D125-H399 IonicContact OD1-CE1 3Å; D125-H399 IonicContact OD1-ND1 3.76Å; D125-H399 PolarHBondContact OD1-ND1 3.04Å; D125-H399 WeakPolarHBondContact OD2-CB 3.43Å; D125-H399 IonicContact OD2-CE1 3.54Å; D125-H399 IonicContact OD2-CG 3.86Å; D125-H399 IonicContact OD2-ND1 4Å; D125-H399 PolarHBondContact OD2-ND1 3.44Å
126	V	96.6	Very high	93.6	Very high	29 Å²	29	20.8 Å²	20.8	18%	0.176	13%	0.125	C	C	.	.	H	α-helix	trans	-63.6	-45.8	173	168.3	0	0	0	0	111.3	L93 N96 H122 V123 L124 I128 C129 V130	L93-V126 HydrophobicContact CD1-CG1 3.89Å; L93-V126 HydrophobicContact CD1-CG2 4.35Å; N96-V126 HydrophobicContact CB-CG2 3.75Å; H122-V126 WeakPolarHBondContact O-CG2 3.4Å; H122-V126 PolarHBondContact O-N 3.45Å; H122-V126 VanDerWaalsContact O-N 3.09Å; V123-V126 PolarHBondContact O-N 3.01Å; L124-V126 VanDerWaalsContact C-N 3.26Å; L124-V126 PolarHBondContact O-N 3.43Å; V126-I128 VanDerWaalsContact C-N 3.31Å; V126-I128 PolarHBondContact O-N 3.23Å; V126-C129 PolarHBondContact O-N 2.89Å; V126-C129 VanDerWaalsContact O-N 3.15Å; V126-V130 HydrophobicContact CG1-CG1 4.41Å; V126-V130 WeakPolarHBondContact O-CG2 3.3Å; V126-V130 PolarHBondContact O-N 3.48Å
127	L	96.5	Very high	93.8	Very high	71 Å²	71	20.1 Å²	20.1	37%	0.372	12%	0.122	S	C	.	.	H	α-helix	trans	-60.2	-40.5	177.6	-70.4	-179.8	0	0	0	112.3	V123 L124 V130 G131 W202	V123-L127 WeakPolarHBondContact O-CG 3.46Å; V123-L127 PolarHBondContact O-N 3.47Å; V123-L127 VanDerWaalsContact O-N 3.07Å; L124-L127 WeakPolarHBondContact O-CB 3.24Å; L124-L127 PolarHBondContact O-N 3.06Å; L124-L127 VanDerWaalsContact O-N 3.08Å; L127-V130 PolarHBondContact O-N 3.4Å; L127-G131 PolarHBondContact O-N 2.92Å; L127-W202 HydrophobicContact CD1-CH2 3.47Å; L127-W202 VanDerWaalsContact CD1-CH2 3.47Å; L127-W202 HydrophobicContact CD1-CZ3 3.55Å
128	I	96.6	Very high	93.8	Very high	1 Å²	1	23 Å²	23	1%	0.005	14%	0.14	C	C	.	.	I	π-helix	trans	-62.7	-45.4	174.9	-66.9	171	0	0	0	110.1	L124 D125 V126 V130 C132 I133 A162 Y393 T396	L124-I128 HydrophobicContact CD1-CD1 4.1Å; L124-I128 HydrophobicContact CD1-CG1 4.23Å; L124-I128 HydrophobicContact CG-CD1 3.98Å; L124-I128 HydrophobicContact CG-CG1 4.49Å; L124-I128 WeakPolarHBondContact O-CG1 3.39Å; L124-I128 PolarHBondContact O-N 3.48Å; D125-I128 PolarHBondContact O-N 3.48Å; V126-I128 VanDerWaalsContact C-N 3.31Å; V126-I128 PolarHBondContact O-N 3.23Å; I128-V130 PolarHBondContact O-N 2.92Å; I128-C132 HydrophobicContact CG2-CB 4.08Å; I128-C132 WeakPolarHBondContact O-CB 3.33Å; I128-C132 PolarHBondContact O-N 2.89Å; I128-I133 HydrophobicContact CG2-CG1 4.28Å; I128-I133 PolarHBondContact O-N 3.32Å; I128-A162 HydrophobicContact CD1-CB 4.03Å; I128-A162 HydrophobicContact CG1-CB 4.06Å; I128-Y393 HydrophobicContact CG2-CD1 3.73Å; I128-Y393 HydrophobicContact CG2-CE1 4.1Å; I128-T396 HydrophobicContact CB-CG2 4.06Å; I128-T396 HydrophobicContact CG2-CG2 3.8Å
129	C	97.1	Very high	93.7	Very high	1 Å²	1	23 Å²	23	1%	0.007	14%	0.14	C	C	.	.	I	π-helix	trans	-64	-35.5	179.6	-66.9	0	0	0	0	114	L93 D125 V126 P134	L93-C129 HydrophobicContact CB-CB 4.43Å; L93-C129 HydrophobicContact CD1-CB 4.39Å; D125-C129 PolarHBondContact O-N 3.11Å; D125-C129 PolarHBondContact O-SG 3.4Å; V126-C129 PolarHBondContact O-N 2.89Å; V126-C129 VanDerWaalsContact O-N 3.15Å; C129-P134 VanDerWaalsContact O-CD 3.25Å; C129-P134 WeakPolarHBondContact O-CD 3.32Å
130	V	96.6	Very high	93.5	Very high	82 Å²	82	21 Å²	21	50%	0.497	13%	0.13	S	C	.	.	I	π-helix	trans	-93	-20.4	-177.5	-56.2	0	0	0	0	113.8	L93 V126 L127 I128	L93-V130 HydrophobicContact CD1-CG1 3.67Å; V126-V130 HydrophobicContact CG1-CG1 4.41Å; V126-V130 WeakPolarHBondContact O-CG2 3.3Å; V126-V130 PolarHBondContact O-N 3.48Å; L127-V130 PolarHBondContact O-N 3.4Å; I128-V130 PolarHBondContact O-N 2.92Å
131	G	94.7	Very high	93.2	Very high	32 Å²	32	24.3 Å²	24.3	33%	0.33	15%	0.147	S	C	.	.	I	π-helix	trans	-110.8	-62.8	-177.7	0	0	0	0	0	113.1	L127 L135	L127-G131 PolarHBondContact O-N 2.92Å; G131-L135 VanDerWaalsContact O-CB 3.28Å; G131-L135 WeakPolarHBondContact O-CB 3.49Å; G131-L135 PolarHBondContact O-N 3.49Å
132	C	95.3	Very high	92.5	Very high	4 Å²	4	27.8 Å²	27.8	3%	0.027	17%	0.165	C	C	.	.	I	π-helix	trans	-71.5	-44.6	-169.7	-56.6	0	0	0	0	112.4	I128 T136 C158 Y393	I128-C132 HydrophobicContact CG2-CB 4.08Å; I128-C132 WeakPolarHBondContact O-CB 3.33Å; I128-C132 PolarHBondContact O-N 2.89Å; C132-T136 PolarHBondContact O-N 3.27Å; C132-T136 PolarHBondContact O-OG1 3.26Å; C132-C158 HydrophobicContact CB-CB 4.31Å; C132-Y393 HydrophobicContact CB-CE1 3.95Å
133	I	95.8	Very high	91	Very high	0 Å²	0	31.1 Å²	31.1	0%	0	19%	0.188	C	C	.	.	H	α-helix	trans	-66.5	-49.8	-177.6	-58.7	-179	0	0	0	111.7	L85 E88 I89 I128 L135 T136 I137 Y393	L85-I133 HydrophobicContact CB-CG2 3.79Å; L85-I133 HydrophobicContact CD2-CG2 3.74Å; L85-I133 HydrophobicContact CG-CG2 4.33Å; E88-I133 HydrophobicContact CB-CD1 3.93Å; I89-I133 HydrophobicContact CD1-CB 4.44Å; I89-I133 HydrophobicContact CD1-CG2 3.83Å; I89-I133 HydrophobicContact CG1-CB 4.07Å; I89-I133 HydrophobicContact CG1-CG2 3.59Å; I128-I133 HydrophobicContact CG2-CG1 4.28Å; I128-I133 PolarHBondContact O-N 3.32Å; I133-L135 VanDerWaalsContact C-N 3.3Å; I133-L135 PolarHBondContact O-N 2.96Å; I133-T136 WeakPolarHBondContact O-CB 3.28Å; I133-T136 PolarHBondContact O-N 3Å; I133-T136 VanDerWaalsContact O-N 3.1Å; I133-I137 HydrophobicContact CG2-CD1 4.42Å; I133-I137 PolarHBondContact O-N 3.14Å; I133-Y393 HydrophobicContact CD1-CG 4.4Å; I133-Y393 HydrophobicContact CG1-CD1 4.41Å; I133-Y393 HydrophobicContact CG1-CD2 3.94Å; I133-Y393 HydrophobicContact CG1-CE2 4.4Å; I133-Y393 HydrophobicContact CG1-CG 3.94Å
134	P	95.5	Very high	89.2	Confident	46 Å²	46	30.9 Å²	30.9	30%	0.299	19%	0.185	S	C	.	.	H	α-helix	trans	-61.6	-38.2	178.6	-25.3	37	0	0	0	112.7	I89 C129 T136 I137 V138	I89-P134 HydrophobicContact CD1-CG 3.99Å; C129-P134 VanDerWaalsContact O-CD 3.25Å; C129-P134 WeakPolarHBondContact O-CD 3.32Å; P134-T136 VanDerWaalsContact C-N 3.31Å; P134-T136 PolarHBondContact O-N 3.4Å; P134-I137 WeakPolarHBondContact O-CB 3.31Å; P134-I137 PolarHBondContact O-N 2.8Å; P134-I137 VanDerWaalsContact O-N 3.14Å; P134-V138 WeakPolarHBondContact O-CG2 3.42Å; P134-V138 PolarHBondContact O-N 3.31Å
135	L	92.2	Very high	87.3	Confident	22 Å²	22	38 Å²	38	12%	0.115	22%	0.218	C	C	.	.	H	α-helix	trans	-63.9	-37.6	175.5	-177.8	66.4	0	0	0	112.3	G131 I133 I137 V138 I139 I151 F154 H155 C158	G131-L135 VanDerWaalsContact O-CB 3.28Å; G131-L135 WeakPolarHBondContact O-CB 3.49Å; G131-L135 PolarHBondContact O-N 3.49Å; I133-L135 VanDerWaalsContact C-N 3.3Å; I133-L135 PolarHBondContact O-N 2.96Å; L135-I137 VanDerWaalsContact C-N 3.3Å; L135-I137 PolarHBondContact O-N 2.96Å; L135-V138 PolarHBondContact O-N 2.98Å; L135-I139 WeakPolarHBondContact O-CG1 3.31Å; L135-I139 PolarHBondContact O-N 3.43Å; L135-I151 HydrophobicContact CD1-CG2 3.96Å; L135-F154 HydrophobicContact CD1-CD1 4.09Å; L135-F154 HydrophobicContact CD2-CD1 3.38Å; L135-F154 HydrophobicContact CD2-CE1 3.9Å; L135-F154 HydrophobicContact CD2-CG 4.42Å; L135-F154 HydrophobicContact CG-CD1 4.37Å; L135-H155 VanDerWaalsContact CD2-CA 3.45Å; L135-H155 HydrophobicContact CD2-CB 4.06Å; L135-H155 HydrophobicContact CG-CB 4.15Å; L135-C158 HydrophobicContact CD2-CB 3.89Å; L135-C158 VanDerWaalsContact CD2-SG 3.56Å
136	T	91.4	Very high	85.2	Confident	1 Å²	1	42.9 Å²	42.9	1%	0.006	25%	0.252	C	S	.	.	H	α-helix	trans	-64	-38.1	173.2	-51.4	0	0	0	0	110.8	L85 C132 I133 P134 I139 L140 H155 L389 Y393	L85-T136 HydrophobicContact CD1-CG2 4.01Å; C132-T136 PolarHBondContact O-N 3.27Å; C132-T136 PolarHBondContact O-OG1 3.26Å; I133-T136 WeakPolarHBondContact O-CB 3.28Å; I133-T136 PolarHBondContact O-N 3Å; I133-T136 VanDerWaalsContact O-N 3.1Å; P134-T136 VanDerWaalsContact C-N 3.31Å; P134-T136 PolarHBondContact O-N 3.4Å; T136-I139 PolarHBondContact O-N 3.01Å; T136-L140 HydrophobicContact CG2-CD1 4.48Å; T136-L140 VanDerWaalsContact O-CG 3.32Å; T136-L140 WeakPolarHBondContact O-CG 2.95Å; T136-L140 PolarHBondContact O-N 3.01Å; T136-H155 PolarHBondContact OG1-NE2 3.05Å; T136-L389 HydrophobicContact CG2-CD2 4.15Å; T136-Y393 HydrophobicContact CG2-CE2 4.24Å; T136-Y393 VanDerWaalsContact OG1-CE2 3.3Å; T136-Y393 WeakPolarHBondContact OG1-CE2 3.44Å; T136-Y393 PolarHBondContact OG1-OH 3.46Å
137	I	92.5	Very high	83.4	Confident	17 Å²	17	47.8 Å²	47.8	9%	0.087	28%	0.278	C	S	.	.	H	α-helix	trans	-63.6	-47	174	-65.3	170.4	0	0	0	110.9	T82 L85 M86 I89 I133 P134 L135 I139 L140 L141	T82-I137 HydrophobicContact CG2-CG1 4.49Å; T82-I137 HydrophobicContact CG2-CG2 3.84Å; L85-I137 HydrophobicContact CB-CD1 3.84Å; L85-I137 HydrophobicContact CB-CG1 3.73Å; L85-I137 HydrophobicContact CD1-CG1 3.85Å; L85-I137 HydrophobicContact CG-CG1 4.42Å; M86-I137 HydrophobicContact CG-CD1 4.04Å; M86-I137 HydrophobicContact SD-CD1 3.57Å; M86-I137 VanDerWaalsContact SD-CD1 3.57Å; I89-I137 HydrophobicContact CD1-CD1 3.86Å; I133-I137 HydrophobicContact CG2-CD1 4.42Å; I133-I137 PolarHBondContact O-N 3.14Å; P134-I137 WeakPolarHBondContact O-CB 3.31Å; P134-I137 PolarHBondContact O-N 2.8Å; P134-I137 VanDerWaalsContact O-N 3.14Å; L135-I137 VanDerWaalsContact C-N 3.3Å; L135-I137 PolarHBondContact O-N 2.96Å; I137-I139 PolarHBondContact O-N 3.45Å; I137-L140 PolarHBondContact O-N 3.15Å; I137-L141 HydrophobicContact CG2-CD1 3.64Å; I137-L141 HydrophobicContact CG2-CG 4.03Å; I137-L141 WeakPolarHBondContact O-CG 3.47Å; I137-L141 PolarHBondContact O-N 3.29Å
138	V	89.4	Confident	82.1	Confident	63 Å²	63	44.8 Å²	44.8	38%	0.382	26%	0.262	S	S	.	.	H	α-helix	trans	-53.5	-47.3	176.5	170.8	0	0	0	0	110.2	P134 L135 L140 L141 L142 I151	P134-V138 WeakPolarHBondContact O-CG2 3.42Å; P134-V138 PolarHBondContact O-N 3.31Å; L135-V138 PolarHBondContact O-N 2.98Å; V138-L140 VanDerWaalsContact C-N 3.31Å; V138-L140 PolarHBondContact O-N 3.41Å; V138-L141 PolarHBondContact O-N 2.77Å; V138-L141 VanDerWaalsContact O-N 3.15Å; V138-L142 WeakPolarHBondContact O-CB 3.38Å; V138-L142 PolarHBondContact O-N 3.31Å; V138-I151 HydrophobicContact CG1-CG2 4.31Å
139	I	83.9	Confident	80.9	Confident	3 Å²	3	45.5 Å²	45.5	2%	0.015	27%	0.268	C	S	.	.	H	α-helix	trans	-61.9	-33.6	177.9	-76.1	-66	0	0	0	113.5	L135 T136 I137 I151 H155 L233	L135-I139 WeakPolarHBondContact O-CG1 3.31Å; L135-I139 PolarHBondContact O-N 3.43Å; T136-I139 PolarHBondContact O-N 3.01Å; I137-I139 PolarHBondContact O-N 3.45Å; I139-I151 HydrophobicContact CD1-CB 4.45Å; I139-I151 HydrophobicContact CD1-CG2 3.73Å; I139-I151 HydrophobicContact CG1-CG2 4.24Å; I139-H155 HydrophobicContact CD1-CB 4.36Å; I139-H155 HydrophobicContact CG1-CB 3.96Å; I139-L233 HydrophobicContact CB-CD2 4.47Å; I139-L233 HydrophobicContact CG2-CD2 3.01Å
140	L	86.1	Confident	79.9	Confident	4 Å²	4	49.4 Å²	49.4	2%	0.021	29%	0.289	C	S	.	.	H	α-helix	trans	-76.3	-26.4	176.1	-70.8	169.6	0	0	0	113.2	Q78 L81 L85 T136 I137 V138 L386	Q78-L140 WeakPolarHBondContact CG-O 3.21Å; Q78-L140 PolarHBondContact NE2-O 2.85Å; L81-L140 HydrophobicContact CB-CD1 4.16Å; L81-L140 HydrophobicContact CD2-CD1 3.78Å; L81-L140 HydrophobicContact CD2-CD2 3.85Å; L81-L140 HydrophobicContact CD2-CG 4.48Å; L81-L140 HydrophobicContact CG-CD1 4.09Å; L85-L140 HydrophobicContact CD1-CD1 3.47Å; L85-L140 VanDerWaalsContact CD1-CD1 3.47Å; T136-L140 HydrophobicContact CG2-CD1 4.48Å; T136-L140 VanDerWaalsContact O-CG 3.32Å; T136-L140 WeakPolarHBondContact O-CG 2.95Å; T136-L140 PolarHBondContact O-N 3.01Å; I137-L140 PolarHBondContact O-N 3.15Å; V138-L140 VanDerWaalsContact C-N 3.31Å; V138-L140 PolarHBondContact O-N 3.41Å; L140-L386 HydrophobicContact CD2-CD1 3.84Å; L140-L386 HydrophobicContact CD2-CD2 4.29Å
141	L	85	Confident	79.2	Confident	88 Å²	88	48.3 Å²	48.3	46%	0.461	28%	0.279	S	S	.	.	H	α-helix	trans	-98.1	-23.5	-174.9	-61.5	-176	0	0	0	113.8	Q78 T82 I137 V138	Q78-L141 HydrophobicContact CG-CD2 3.78Å; T82-L141 HydrophobicContact CG2-CD2 4.43Å; I137-L141 HydrophobicContact CG2-CD1 3.64Å; I137-L141 HydrophobicContact CG2-CG 4.03Å; I137-L141 WeakPolarHBondContact O-CG 3.47Å; I137-L141 PolarHBondContact O-N 3.29Å; V138-L141 PolarHBondContact O-N 2.77Å; V138-L141 VanDerWaalsContact O-N 3.15Å
142	L	77.8	Confident	78.3	Confident	72 Å²	72	46.8 Å²	46.8	38%	0.377	26%	0.264	S	S	.	.	S	Bend	trans	-77.8	128.5	-178.4	-145.2	80.8	0	0	0	110.3	V138 L144 T148 I151	V138-L142 WeakPolarHBondContact O-CB 3.38Å; V138-L142 PolarHBondContact O-N 3.31Å; L142-L144 PolarHBondContact O-N 2.86Å; L142-T148 HydrophobicContact CD2-CG2 3.67Å; L142-I151 HydrophobicContact CD2-CD1 4.24Å
143	S	60.6	Low	77.5	Confident	70 Å²	70	46.9 Å²	46.9	49%	0.49	26%	0.264	S	S	.	.			trans	-67.4	121.1	162.2	-61.3	0	0	0	0	108	E145	S143-E145 VanDerWaalsContact C-N 3.28Å; S143-E145 PolarHBondContact O-N 2.92Å
144	L	57.6	Low	77	Confident	42 Å²	42	51.5 Å²	51.5	22%	0.22	29%	0.285	C	S	.	.			trans	-73	80.5	-174.2	-79.1	92.1	0	0	0	111.5	L142 L233 C234	L142-L144 PolarHBondContact O-N 2.86Å; L144-L233 WeakPolarHBondContact CD2-O 3.37Å; L144-C234 HydrophobicContact CD2-CB 4.14Å; L144-C234 VanDerWaalsContact CD2-SG 3.6Å
145	E	55.4	Low	76.6	Confident	149 Å²	149	49.4 Å²	49.4	70%	0.696	27%	0.271	S	S	*	.			trans	-80.6	167	165.6	-71.2	-178.5	179	0	0	111.2	S143 N147 T148	S143-E145 VanDerWaalsContact C-N 3.28Å; S143-E145 PolarHBondContact O-N 2.92Å; E145-N147 PolarHBondContact O-N 2.78Å; E145-T148 PolarHBondContact O-N 2.94Å; E145-T148 PolarHBondContact O-OG1 3.12Å
146	S	53.5	Low	76.2	Confident	103 Å²	103	48.4 Å²	48.4	72%	0.72	27%	0.266	S	S	*	.	T	Hydrogen-bonded Turn	trans	-56.3	-11.3	-168.9	53.6	0	0	0	0	116.5
147	N	58.9	Low	76	Confident	133 Å²	133	48.4 Å²	48.4	71%	0.711	27%	0.266	S	S	*	.	T	Hydrogen-bonded Turn	trans	-103.2	14.8	-178.7	-154.5	16.3	0	0	0	114.7	E145	E145-N147 PolarHBondContact O-N 2.78Å
148	T	69.2	Low	76	Confident	7 Å²	7	48 Å²	48	4%	0.043	26%	0.264	C	S	.	.			trans	-91.2	-3.6	-173.7	-47.4	0	0	0	0	114.2	L142 E145 L150 I151 C152	L142-T148 HydrophobicContact CD2-CG2 3.67Å; E145-T148 PolarHBondContact O-N 2.94Å; E145-T148 PolarHBondContact O-OG1 3.12Å; T148-L150 VanDerWaalsContact C-N 3.32Å; T148-L150 PolarHBondContact O-N 3.35Å; T148-I151 HydrophobicContact CG2-CB 4.19Å; T148-I151 HydrophobicContact CG2-CD1 4.46Å; T148-I151 PolarHBondContact O-N 3.48Å; T148-C152 PolarHBondContact O-N 3.39Å; T148-C152 VanDerWaalsContact O-N 3.09Å
149	A	71	Confident	75.9	Confident	16 Å²	16	45 Å²	45	13%	0.132	25%	0.246	C	C	.	.	H	α-helix	trans	-49.7	-46.7	-175.3	0	0	0	0	0	114	I151 C152 C153 N229	A149-I151 PolarHBondContact O-N 3.48Å; A149-C152 PolarHBondContact O-N 3.05Å; A149-C153 WeakPolarHBondContact O-CB 3.2Å; A149-C153 PolarHBondContact O-N 3.15Å; A149-N229 WeakPolarHBondContact CA-OD1 3.49Å; A149-N229 WeakPolarHBondContact CB-OD1 3.38Å
150	L	76.3	Confident	76.1	Confident	83 Å²	83	45.1 Å²	45.1	44%	0.435	25%	0.247	S	C	.	.	H	α-helix	trans	-66.3	-38.5	-177.5	-68.9	175	0	0	0	112.2	T148 C153 F154 F218	T148-L150 VanDerWaalsContact C-N 3.32Å; T148-L150 PolarHBondContact O-N 3.35Å; L150-C153 PolarHBondContact O-N 3.07Å; L150-F154 VanDerWaalsContact O-CB 3.32Å; L150-F154 WeakPolarHBondContact O-CB 3.47Å; L150-F154 PolarHBondContact O-N 3.42Å; L150-F218 HydrophobicContact CD2-CD2 4.32Å; L150-F218 HydrophobicContact CD2-CE2 3.73Å
151	I	80.4	Confident	76.4	Confident	59 Å²	59	46.3 Å²	46.3	30%	0.303	25%	0.252	S	S	.	.	H	α-helix	trans	-68.4	-42.3	179.2	-55.7	178.1	0	0	0	109.6	L135 V138 I139 L142 T148 A149 F154 H155	L135-I151 HydrophobicContact CD1-CG2 3.96Å; V138-I151 HydrophobicContact CG1-CG2 4.31Å; I139-I151 HydrophobicContact CD1-CB 4.45Å; I139-I151 HydrophobicContact CD1-CG2 3.73Å; I139-I151 HydrophobicContact CG1-CG2 4.24Å; L142-I151 HydrophobicContact CD2-CD1 4.24Å; T148-I151 HydrophobicContact CG2-CB 4.19Å; T148-I151 HydrophobicContact CG2-CD1 4.46Å; T148-I151 PolarHBondContact O-N 3.48Å; A149-I151 PolarHBondContact O-N 3.48Å; I151-F154 PolarHBondContact O-N 3.47Å; I151-H155 VanDerWaalsContact O-CB 3.28Å; I151-H155 WeakPolarHBondContact O-CB 3.44Å; I151-H155 PolarHBondContact O-N 2.96Å
152	C	77.3	Confident	76.7	Confident	1 Å²	1	42.1 Å²	42.1	1%	0.007	23%	0.23	C	C	.	.	H	α-helix	trans	-61.8	-43.9	173.4	-83.9	0	0	0	0	112.5	T148 A149 H155 E156 T231 C234	T148-C152 PolarHBondContact O-N 3.39Å; T148-C152 VanDerWaalsContact O-N 3.09Å; A149-C152 PolarHBondContact O-N 3.05Å; C152-H155 WeakPolarHBondContact O-CB 3.37Å; C152-H155 PolarHBondContact O-N 2.95Å; C152-E156 PolarHBondContact O-N 3.39Å; C152-T231 HydrophobicContact CB-CG2 4.19Å; C152-C234 HydrophobicContact CB-CB 3.76Å; C152-C234 WeakPolarHBondContact CB-SG 3.48Å; C152-C234 WeakPolarHBondContact SG-CB 3.29Å; C152-C234 CovalentContact SG-SG 2.03Å; C152-C234 PolarHBondContact SG-SG 2.89Å
153	C	78.3	Confident	77.3	Confident	5 Å²	5	39.1 Å²	39.1	3%	0.034	22%	0.215	C	C	.	.	H	α-helix	trans	-61.8	-46.1	176	-175	0	0	0	0	111.6	A149 L150 H155 E156 A157	A149-C153 WeakPolarHBondContact O-CB 3.2Å; A149-C153 PolarHBondContact O-N 3.15Å; L150-C153 PolarHBondContact O-N 3.07Å; C153-H155 VanDerWaalsContact C-N 3.29Å; C153-H155 PolarHBondContact O-N 3.21Å; C153-E156 PolarHBondContact O-N 3Å; C153-A157 WeakPolarHBondContact O-CB 3.45Å; C153-A157 PolarHBondContact O-N 3.46Å
154	F	85.4	Confident	78.6	Confident	98 Å²	98	36 Å²	36	43%	0.43	19%	0.193	S	C	.	.	H	α-helix	trans	-63.9	-36.6	177.1	-165.4	-96.6	0	0	0	111.4	L135 L150 I151 A157 C158 F209 F213	L135-F154 HydrophobicContact CD1-CD1 4.09Å; L135-F154 HydrophobicContact CD2-CD1 3.38Å; L135-F154 HydrophobicContact CD2-CE1 3.9Å; L135-F154 HydrophobicContact CD2-CG 4.42Å; L135-F154 HydrophobicContact CG-CD1 4.37Å; L150-F154 VanDerWaalsContact O-CB 3.32Å; L150-F154 WeakPolarHBondContact O-CB 3.47Å; L150-F154 PolarHBondContact O-N 3.42Å; I151-F154 PolarHBondContact O-N 3.47Å; F154-A157 WeakPolarHBondContact O-CB 3.29Å; F154-A157 PolarHBondContact O-N 3.47Å; F154-C158 PolarHBondContact O-N 3.39Å; F154-F209 AromaticContact CD2-CZ 3.95Å; F154-F209 HydrophobicContact CD2-CZ 3.95Å; F154-F209 HydrophobicContact CE2-CE1 4.45Å; F154-F209 HydrophobicContact CE2-CE2 4.41Å; F154-F209 AromaticContact CE2-CZ 3.57Å; F154-F209 HydrophobicContact CE2-CZ 3.57Å; F154-F209 HydrophobicContact CZ-CZ 4.03Å; F154-F213 HydrophobicContact CB-CZ 4.4Å; F154-F213 AromaticContact CD2-CZ 3.88Å; F154-F213 HydrophobicContact CD2-CZ 3.88Å
155	H	87.1	Confident	80.3	Confident	1 Å²	1	34 Å²	34	1%	0.005	18%	0.183	C	C	.	.	H	α-helix	trans	-61	-50.7	173.6	173.4	-93.9	0	0	0	111.9	L135 T136 I139 I151 C152 C153 A157 C158 V159	L135-H155 VanDerWaalsContact CD2-CA 3.45Å; L135-H155 HydrophobicContact CD2-CB 4.06Å; L135-H155 HydrophobicContact CG-CB 4.15Å; T136-H155 PolarHBondContact OG1-NE2 3.05Å; I139-H155 HydrophobicContact CD1-CB 4.36Å; I139-H155 HydrophobicContact CG1-CB 3.96Å; I151-H155 VanDerWaalsContact O-CB 3.28Å; I151-H155 WeakPolarHBondContact O-CB 3.44Å; I151-H155 PolarHBondContact O-N 2.96Å; C152-H155 WeakPolarHBondContact O-CB 3.37Å; C152-H155 PolarHBondContact O-N 2.95Å; C153-H155 VanDerWaalsContact C-N 3.29Å; C153-H155 PolarHBondContact O-N 3.21Å; H155-A157 VanDerWaalsContact C-N 3.27Å; H155-A157 PolarHBondContact O-N 3.31Å; H155-C158 WeakPolarHBondContact O-CB 3.45Å; H155-C158 PolarHBondContact O-N 3.33Å; H155-C158 VanDerWaalsContact O-N 3.15Å; H155-V159 WeakPolarHBondContact O-CG2 3.41Å; H155-V159 PolarHBondContact O-N 2.88Å
156	E	84.2	Confident	82	Confident	2 Å²	2	27 Å²	27	1%	0.009	15%	0.15	C	C	.	.	H	α-helix	trans	-63.4	-34.4	177.5	-67.8	-56.7	156	0	0	112.7	C152 C153 V159 S160 P212 T231 H249 R385	C152-E156 PolarHBondContact O-N 3.39Å; C153-E156 PolarHBondContact O-N 3Å; E156-V159 PolarHBondContact O-N 3.33Å; E156-S160 WeakPolarHBondContact O-CB 3.37Å; E156-S160 PolarHBondContact O-N 2.77Å; E156-S160 PolarHBondContact O-OG 2.9Å; E156-P212 HydrophobicContact CB-CB 4.38Å; E156-P212 HydrophobicContact CB-CG 4.36Å; E156-T231 HydrophobicContact CB-CG2 4.37Å; E156-T231 HydrophobicContact CG-CG2 3.46Å; E156-T231 VanDerWaalsContact CG-CG2 3.46Å; E156-H249 IonicContact OE2-NE2 3.22Å; E156-R385 VanDerWaalsContact CD-NH2 3.34Å; E156-R385 IonicContact OE1-CZ 2.85Å; E156-R385 IonicContact OE1-NH1 3.46Å; E156-R385 PolarHBondContact OE1-NH1 3.44Å; E156-R385 IonicContact OE1-NH2 3.72Å; E156-R385 PolarHBondContact OE1-NH2 3.39Å; E156-R385 IonicContact OE2-CZ 3.99Å; E156-R385 IonicContact OE2-NH1 3.67Å; E156-R385 IonicContact OE2-NH2 2.74Å; E156-R385 PolarHBondContact OE2-NH2 2.79Å
157	A	87.1	Confident	83.8	Confident	0 Å²	0	22.1 Å²	22.1	0%	0	12%	0.117	C	C	.	.	H	α-helix	trans	-62.8	-45.1	172.1	0	0	0	0	0	112.1	C153 F154 H155 S160 F161 F209 P212 F213	C153-A157 WeakPolarHBondContact O-CB 3.45Å; C153-A157 PolarHBondContact O-N 3.46Å; F154-A157 WeakPolarHBondContact O-CB 3.29Å; F154-A157 PolarHBondContact O-N 3.47Å; H155-A157 VanDerWaalsContact C-N 3.27Å; H155-A157 PolarHBondContact O-N 3.31Å; A157-S160 PolarHBondContact O-N 3.3Å; A157-F161 WeakPolarHBondContact O-CB 3.25Å; A157-F161 PolarHBondContact O-N 2.89Å; A157-F209 VanDerWaalsContact C-CD2 3.49Å; A157-F209 HydrophobicContact CB-CD1 4.44Å; A157-F209 HydrophobicContact CB-CD2 3.71Å; A157-F209 HydrophobicContact CB-CE1 4.3Å; A157-F209 HydrophobicContact CB-CE2 3.53Å; A157-F209 HydrophobicContact CB-CG 4.16Å; A157-F209 HydrophobicContact CB-CZ 3.85Å; A157-F209 VanDerWaalsContact CB-O 3.22Å; A157-F209 WeakPolarHBondContact CB-O 3.42Å; A157-F209 WeakPolarHBondContact O-CD2 3.46Å; A157-P212 HydrophobicContact CB-CB 4.46Å; A157-P212 HydrophobicContact CB-CG 4.24Å; A157-F213 HydrophobicContact CB-CD2 4.15Å; A157-F213 HydrophobicContact CB-CE2 3.42Å; A157-F213 VanDerWaalsContact CB-CE2 3.42Å; A157-F213 HydrophobicContact CB-CZ 4.14Å
158	C	91.1	Very high	85.2	Confident	9 Å²	9	17.3 Å²	17.3	6%	0.061	9%	0.09	C	C	.	.	H	α-helix	trans	-62.1	-43.2	174.4	-80.1	0	0	0	0	112.5	C132 L135 F154 H155 F161 A162	C132-C158 HydrophobicContact CB-CB 4.31Å; L135-C158 HydrophobicContact CD2-CB 3.89Å; L135-C158 VanDerWaalsContact CD2-SG 3.56Å; F154-C158 PolarHBondContact O-N 3.39Å; H155-C158 WeakPolarHBondContact O-CB 3.45Å; H155-C158 PolarHBondContact O-N 3.33Å; H155-C158 VanDerWaalsContact O-N 3.15Å; C158-F161 PolarHBondContact O-N 3.44Å; C158-A162 WeakPolarHBondContact O-CB 3.11Å; C158-A162 PolarHBondContact O-N 2.81Å
159	V	88.6	Confident	86.3	Confident	1 Å²	1	17.1 Å²	17.1	1%	0.006	9%	0.089	C	C	.	.	H	α-helix	trans	-61.6	-45.1	176.3	172.3	0	0	0	0	110.7	H155 E156 A162 S163 L389	H155-V159 WeakPolarHBondContact O-CG2 3.41Å; H155-V159 PolarHBondContact O-N 2.88Å; E156-V159 PolarHBondContact O-N 3.33Å; V159-A162 PolarHBondContact O-N 2.99Å; V159-S163 WeakPolarHBondContact O-CB 3.28Å; V159-S163 PolarHBondContact O-N 3.46Å; V159-S163 PolarHBondContact O-OG 3.48Å; V159-L389 HydrophobicContact CG1-CD1 3.95Å; V159-L389 HydrophobicContact CG2-CD1 4.02Å; V159-L389 HydrophobicContact CG2-CD2 3.84Å
160	S	87.6	Confident	87.2	Confident	4 Å²	4	16.3 Å²	16.3	3%	0.028	8%	0.083	C	C	.	.	H	α-helix	trans	-60.4	-50.6	176.8	-62.3	0	0	0	0	110.9	E156 A157 A162 S163 V164	E156-S160 WeakPolarHBondContact O-CB 3.37Å; E156-S160 PolarHBondContact O-N 2.77Å; E156-S160 PolarHBondContact O-OG 2.9Å; A157-S160 PolarHBondContact O-N 3.3Å; S160-A162 PolarHBondContact O-N 2.77Å; S160-S163 PolarHBondContact O-N 3.29Å; S160-S163 PolarHBondContact O-OG 2.95Å; S160-V164 PolarHBondContact O-N 2.93Å
161	F	91.5	Very high	87.7	Confident	29 Å²	29	14.5 Å²	14.5	13%	0.127	7%	0.071	C	C	.	.	H	α-helix	trans	-55.1	-50.3	174.7	170.5	-94.2	0	0	0	112.5	L124 A157 C158 S163 V164 S165 W202 F209	L124-F161 HydrophobicContact CD1-CE1 3.81Å; L124-F161 HydrophobicContact CD1-CZ 3.92Å; A157-F161 WeakPolarHBondContact O-CB 3.25Å; A157-F161 PolarHBondContact O-N 2.89Å; C158-F161 PolarHBondContact O-N 3.44Å; F161-S163 VanDerWaalsContact C-N 3.29Å; F161-S163 PolarHBondContact O-N 2.89Å; F161-V164 PolarHBondContact O-N 3.25Å; F161-S165 WeakPolarHBondContact CD2-OG 3.33Å; F161-S165 WeakPolarHBondContact CE2-OG 3.28Å; F161-S165 WeakPolarHBondContact O-CB 3.31Å; F161-S165 PolarHBondContact O-N 3.04Å; F161-S165 PolarHBondContact O-OG 3.29Å; F161-W202 HydrophobicContact CZ-CZ3 4.07Å; F161-F209 HydrophobicContact CB-CB 4.1Å; F161-F209 HydrophobicContact CB-CD2 3.93Å; F161-F209 HydrophobicContact CD2-CB 4.42Å
162	A	92.8	Very high	88.2	Confident	0 Å²	0	11.7 Å²	11.7	0%	0	6%	0.057	C	C	.	.	H	α-helix	trans	-59.7	-43.5	-178	0	0	0	0	0	110.8	I128 C158 V159 S160 T166 W362 Y393	I128-A162 HydrophobicContact CD1-CB 4.03Å; I128-A162 HydrophobicContact CG1-CB 4.06Å; C158-A162 WeakPolarHBondContact O-CB 3.11Å; C158-A162 PolarHBondContact O-N 2.81Å; V159-A162 PolarHBondContact O-N 2.99Å; S160-A162 PolarHBondContact O-N 2.77Å; A162-T166 WeakPolarHBondContact O-CB 3.35Å; A162-T166 PolarHBondContact O-N 3.49Å; A162-T166 PolarHBondContact O-OG1 3.38Å; A162-W362 HydrophobicContact CB-CH2 4.08Å; A162-Y393 HydrophobicContact CB-CE1 4.19Å
163	S	89.6	Confident	88.7	Confident	9 Å²	9	11.7 Å²	11.7	6%	0.063	6%	0.057	C	C	.	.	H	α-helix	trans	-64.8	-51.9	-179.6	74.2	0	0	0	0	113.2	V159 S160 F161 T166 A167 Q253	V159-S163 WeakPolarHBondContact O-CB 3.28Å; V159-S163 PolarHBondContact O-N 3.46Å; V159-S163 PolarHBondContact O-OG 3.48Å; S160-S163 PolarHBondContact O-N 3.29Å; S160-S163 PolarHBondContact O-OG 2.95Å; F161-S163 VanDerWaalsContact C-N 3.29Å; F161-S163 PolarHBondContact O-N 2.89Å; S163-T166 PolarHBondContact O-N 3.24Å; S163-A167 WeakPolarHBondContact O-CB 3.47Å; S163-A167 PolarHBondContact O-N 3Å; S163-Q253 PolarHBondContact OG-NE2 3.45Å
164	V	88.3	Confident	89.1	Confident	5 Å²	5	11.5 Å²	11.5	3%	0.03	6%	0.055	C	C	.	.	H	α-helix	trans	-70.5	-44.4	-175.5	173.3	0	0	0	0	110	S160 F161 T166 A167 I168 S208 I256	S160-V164 PolarHBondContact O-N 2.93Å; F161-V164 PolarHBondContact O-N 3.25Å; V164-T166 VanDerWaalsContact C-N 3.33Å; V164-T166 PolarHBondContact O-N 3.35Å; V164-A167 PolarHBondContact O-N 3.04Å; V164-I168 HydrophobicContact CG1-CD1 3.54Å; V164-I168 HydrophobicContact CG1-CG1 4.23Å; V164-I168 VanDerWaalsContact O-CG1 3.29Å; V164-I168 WeakPolarHBondContact O-CG1 3.16Å; V164-I168 PolarHBondContact O-N 3.1Å; V164-S208 VanDerWaalsContact CG2-OG 3.22Å; V164-S208 WeakPolarHBondContact CG2-OG 3.1Å; V164-I256 HydrophobicContact CG2-CD1 4.28Å; V164-I256 HydrophobicContact CG2-CG2 4.25Å
165	S	92.1	Very high	89.3	Confident	1 Å²	1	9.4 Å²	9.4	1%	0.007	5%	0.048	C	C	.	.	H	α-helix	trans	-59.5	-44.7	177.5	-55.9	0	0	0	0	111.7	L124 F161 N169 S205	L124-S165 VanDerWaalsContact CD1-CB 3.43Å; L124-S165 VanDerWaalsContact CD2-C 3.46Å; F161-S165 WeakPolarHBondContact CD2-OG 3.33Å; F161-S165 WeakPolarHBondContact CE2-OG 3.28Å; F161-S165 WeakPolarHBondContact O-CB 3.31Å; F161-S165 PolarHBondContact O-N 3.04Å; F161-S165 PolarHBondContact O-OG 3.29Å; S165-N169 VanDerWaalsContact O-CB 3.32Å; S165-N169 WeakPolarHBondContact O-CB 3.17Å; S165-N169 PolarHBondContact O-N 2.89Å; S165-N169 PolarHBondContact O-ND2 2.83Å; S165-S205 WeakPolarHBondContact CA-OG 3.48Å; S165-S205 WeakPolarHBondContact CB-OG 3.47Å; S165-S205 WeakPolarHBondContact OG-CB 3.47Å; S165-S205 PolarHBondContact OG-OG 3.49Å
166	T	92.8	Very high	89.3	Confident	0 Å²	0	9.3 Å²	9.3	0%	0	5%	0.048	C	C	.	.	H	α-helix	trans	-65.4	-46	180	-56.1	0	0	0	0	110.4	A162 S163 V164 I168 N169 V170 F358 W362	A162-T166 WeakPolarHBondContact O-CB 3.35Å; A162-T166 PolarHBondContact O-N 3.49Å; A162-T166 PolarHBondContact O-OG1 3.38Å; S163-T166 PolarHBondContact O-N 3.24Å; V164-T166 VanDerWaalsContact C-N 3.33Å; V164-T166 PolarHBondContact O-N 3.35Å; T166-I168 PolarHBondContact O-N 3.34Å; T166-N169 PolarHBondContact O-N 3Å; T166-V170 HydrophobicContact CG2-CG2 4.37Å; T166-V170 WeakPolarHBondContact O-CB 3.15Å; T166-V170 VanDerWaalsContact O-CG2 3.27Å; T166-V170 WeakPolarHBondContact O-CG2 3.41Å; T166-V170 PolarHBondContact O-N 3.24Å; T166-F358 HydrophobicContact CG2-CD2 3.77Å; T166-F358 HydrophobicContact CG2-CE2 3.95Å; T166-W362 HydrophobicContact CG2-CZ2 4.47Å
167	A	89.6	Confident	89.4	Confident	2 Å²	2	10 Å²	10	2%	0.017	5%	0.05	C	C	.	.	H	α-helix	trans	-58.8	-48.6	179.5	0	0	0	0	0	112.3	S163 V164 V170 F171 T260 F358	S163-A167 WeakPolarHBondContact O-CB 3.47Å; S163-A167 PolarHBondContact O-N 3Å; V164-A167 PolarHBondContact O-N 3.04Å; A167-V170 PolarHBondContact O-N 2.58Å; A167-F171 WeakPolarHBondContact O-CB 3.35Å; A167-F171 PolarHBondContact O-N 2.94Å; A167-T260 HydrophobicContact CB-CG2 3.77Å; A167-F358 HydrophobicContact CB-CE2 4.08Å; A167-F358 HydrophobicContact CB-CZ 3.65Å
168	I	89.6	Confident	89.3	Confident	32 Å²	32	13.1 Å²	13.1	16%	0.164	6%	0.063	C	C	.	.	H	α-helix	trans	-72.7	-33.5	-177.6	-52	169.6	0	0	0	111.3	V164 T166 F171 A172 I201 F204	V164-I168 HydrophobicContact CG1-CD1 3.54Å; V164-I168 HydrophobicContact CG1-CG1 4.23Å; V164-I168 VanDerWaalsContact O-CG1 3.29Å; V164-I168 WeakPolarHBondContact O-CG1 3.16Å; V164-I168 PolarHBondContact O-N 3.1Å; T166-I168 PolarHBondContact O-N 3.34Å; I168-F171 WeakPolarHBondContact O-CB 3.25Å; I168-F171 PolarHBondContact O-N 3.37Å; I168-A172 PolarHBondContact O-N 2.94Å; I168-I201 HydrophobicContact CB-CG2 4.39Å; I168-I201 HydrophobicContact CG2-CB 4.47Å; I168-I201 HydrophobicContact CG2-CD1 4.17Å; I168-I201 HydrophobicContact CG2-CG1 3.61Å; I168-I201 HydrophobicContact CG2-CG2 4.34Å; I168-F204 HydrophobicContact CD1-CB 4.09Å
169	N	91.6	Very high	89.1	Confident	2 Å²	2	13 Å²	13	1%	0.011	6%	0.061	C	C	.	.	H	α-helix	trans	-65	-43.1	173.4	-86.8	-87.5	0	0	0	112.2	N120 L121 L124 S165 T166 F171 A172 I173 I201	N120-N169 PolarHBondContact ND2-OD1 3.42Å; L121-N169 HydrophobicContact CD1-CB 3.91Å; L124-N169 HydrophobicContact CD2-CB 4.3Å; S165-N169 VanDerWaalsContact O-CB 3.32Å; S165-N169 WeakPolarHBondContact O-CB 3.17Å; S165-N169 PolarHBondContact O-N 2.89Å; S165-N169 PolarHBondContact O-ND2 2.83Å; T166-N169 PolarHBondContact O-N 3Å; N169-F171 VanDerWaalsContact C-N 3.27Å; N169-F171 PolarHBondContact O-N 3.47Å; N169-A172 WeakPolarHBondContact O-CB 3.36Å; N169-A172 PolarHBondContact O-N 3.43Å; N169-I173 WeakPolarHBondContact O-CG1 3.21Å; N169-I173 PolarHBondContact O-N 3.34Å; N169-I201 WeakPolarHBondContact ND2-CG2 3.39Å
170	V	89.4	Confident	88.9	Confident	0 Å²	0	14.5 Å²	14.5	0%	0	7%	0.069	C	C	.	.	H	α-helix	trans	-64.3	-35.7	174.7	174.8	0	0	0	0	111	T166 A167 I173 T174 M264 I354 I355 F358	T166-V170 HydrophobicContact CG2-CG2 4.37Å; T166-V170 WeakPolarHBondContact O-CB 3.15Å; T166-V170 VanDerWaalsContact O-CG2 3.27Å; T166-V170 WeakPolarHBondContact O-CG2 3.41Å; T166-V170 PolarHBondContact O-N 3.24Å; A167-V170 PolarHBondContact O-N 2.58Å; V170-I173 PolarHBondContact O-N 3.46Å; V170-T174 PolarHBondContact O-N 2.92Å; V170-T174 PolarHBondContact O-OG1 3.1Å; V170-M264 HydrophobicContact CG1-CE 3.47Å; V170-M264 VanDerWaalsContact CG1-CE 3.47Å; V170-M264 HydrophobicContact CG1-SD 3.87Å; V170-I354 HydrophobicContact CG2-CG2 4.3Å; V170-I355 HydrophobicContact CG1-CG1 3.69Å; V170-F358 HydrophobicContact CG1-CB 4.34Å; V170-F358 HydrophobicContact CG1-CG 4.37Å; V170-F358 HydrophobicContact CG2-CB 4.26Å; V170-F358 HydrophobicContact CG2-CD2 4.19Å; V170-F358 HydrophobicContact CG2-CG 4.24Å
171	F	87.9	Confident	88.5	Confident	45 Å²	45	14.8 Å²	14.8	20%	0.197	7%	0.071	C	C	.	.	H	α-helix	trans	-64.5	-42.3	171.5	175.2	-122.7	0	0	0	112.6	A167 I168 N169 I173 T174 L175 V263	A167-F171 WeakPolarHBondContact O-CB 3.35Å; A167-F171 PolarHBondContact O-N 2.94Å; I168-F171 WeakPolarHBondContact O-CB 3.25Å; I168-F171 PolarHBondContact O-N 3.37Å; N169-F171 VanDerWaalsContact C-N 3.27Å; N169-F171 PolarHBondContact O-N 3.47Å; F171-I173 VanDerWaalsContact C-N 3.33Å; F171-I173 PolarHBondContact O-N 2.9Å; F171-T174 CarbonylContact O-C 3.6Å; F171-T174 WeakPolarHBondContact O-CA 3.46Å; F171-T174 VanDerWaalsContact O-CB 3.23Å; F171-T174 WeakPolarHBondContact O-CB 3.48Å; F171-T174 PolarHBondContact O-N 3.19Å; F171-L175 HydrophobicContact CD1-CD1 4.27Å; F171-L175 HydrophobicContact CD2-CG 4.27Å; F171-L175 HydrophobicContact CE1-CD1 3.65Å; F171-L175 HydrophobicContact CE1-CG 4.17Å; F171-L175 HydrophobicContact CE2-CD1 4.11Å; F171-L175 HydrophobicContact CE2-CD2 3.72Å; F171-L175 HydrophobicContact CE2-CG 3.69Å; F171-L175 HydrophobicContact CZ-CD1 3.57Å; F171-L175 HydrophobicContact CZ-CD2 3.72Å; F171-L175 HydrophobicContact CZ-CG 3.68Å; F171-L175 PolarHBondContact O-N 3.39Å; F171-V263 HydrophobicContact CD2-CG1 3.89Å; F171-V263 HydrophobicContact CE2-CB 4.28Å; F171-V263 HydrophobicContact CE2-CG1 3.2Å; F171-V263 HydrophobicContact CZ-CG1 3.8Å
172	A	90	Very high	88	Confident	0 Å²	0	15.4 Å²	15.4	0%	0	8%	0.077	C	C	.	.	H	α-helix	trans	-61	-41	175.5	0	0	0	0	0	112.2	I117 I168 N169 T174 L175 D176 L197 I201	I117-A172 HydrophobicContact CG2-CB 4.07Å; I168-A172 PolarHBondContact O-N 2.94Å; N169-A172 WeakPolarHBondContact O-CB 3.36Å; N169-A172 PolarHBondContact O-N 3.43Å; A172-T174 VanDerWaalsContact C-N 3.26Å; A172-T174 PolarHBondContact O-N 2.93Å; A172-L175 PolarHBondContact O-N 3.08Å; A172-D176 PolarHBondContact O-N 3.1Å; A172-L197 HydrophobicContact CB-CD2 4.09Å; A172-I201 HydrophobicContact CB-CD1 3.77Å
173	I	88.8	Confident	87.3	Confident	1 Å²	1	19.4 Å²	19.4	1%	0.005	10%	0.095	C	C	.	.	H	α-helix	trans	-58.9	-43.3	171.8	-67	167.2	0	0	0	109.9	I117 L121 N169 V170 F171 L175 D176 R177 I354	I117-I173 HydrophobicContact CG2-CB 4.48Å; I117-I173 HydrophobicContact CG2-CG1 3.65Å; L121-I173 HydrophobicContact CB-CD1 4.42Å; L121-I173 HydrophobicContact CD2-CD1 3.75Å; L121-I173 HydrophobicContact CG-CD1 4.47Å; N169-I173 WeakPolarHBondContact O-CG1 3.21Å; N169-I173 PolarHBondContact O-N 3.34Å; V170-I173 PolarHBondContact O-N 3.46Å; F171-I173 VanDerWaalsContact C-N 3.33Å; F171-I173 PolarHBondContact O-N 2.9Å; I173-L175 PolarHBondContact O-N 3.12Å; I173-D176 PolarHBondContact O-N 3.32Å; I173-R177 HydrophobicContact CG2-CG 4.4Å; I173-R177 WeakPolarHBondContact O-CG 3.33Å; I173-R177 PolarHBondContact O-N 3.35Å; I173-I354 HydrophobicContact CD1-CG2 4.48Å
174	T	87.1	Confident	86.7	Confident	0 Å²	0	22.2 Å²	22.2	0%	0	11%	0.113	C	C	.	.	H	α-helix	trans	-62.2	-42.8	178.6	-61.4	0	0	0	0	112.5	V170 F171 A172 R177 Y178 T267 Y268 I355	V170-T174 PolarHBondContact O-N 2.92Å; V170-T174 PolarHBondContact O-OG1 3.1Å; F171-T174 CarbonylContact O-C 3.6Å; F171-T174 WeakPolarHBondContact O-CA 3.46Å; F171-T174 VanDerWaalsContact O-CB 3.23Å; F171-T174 WeakPolarHBondContact O-CB 3.48Å; F171-T174 PolarHBondContact O-N 3.19Å; A172-T174 VanDerWaalsContact C-N 3.26Å; A172-T174 PolarHBondContact O-N 2.93Å; T174-R177 PolarHBondContact O-N 3.25Å; T174-Y178 WeakPolarHBondContact O-CB 3.36Å; T174-Y178 PolarHBondContact O-N 3.28Å; T174-T267 HydrophobicContact CG2-CG2 4.32Å; T174-T267 WeakPolarHBondContact CG2-OG1 3.22Å; T174-Y268 HydrophobicContact CG2-CD2 3.77Å; T174-Y268 HydrophobicContact CG2-CE2 3.46Å; T174-Y268 VanDerWaalsContact CG2-CE2 3.46Å; T174-I355 VanDerWaalsContact OG1-CD1 3.24Å; T174-I355 WeakPolarHBondContact OG1-CD1 3.33Å
175	L	87.9	Confident	86.1	Confident	54 Å²	54	26.3 Å²	26.3	28%	0.283	15%	0.147	S	C	.	.	H	α-helix	trans	-62.6	-45	175.6	-71	179.8	0	0	0	112.4	F171 A172 I173 R177 Y178 D179 L197	F171-L175 HydrophobicContact CD1-CD1 4.27Å; F171-L175 HydrophobicContact CD2-CG 4.27Å; F171-L175 HydrophobicContact CE1-CD1 3.65Å; F171-L175 HydrophobicContact CE1-CG 4.17Å; F171-L175 HydrophobicContact CE2-CD1 4.11Å; F171-L175 HydrophobicContact CE2-CD2 3.72Å; F171-L175 HydrophobicContact CE2-CG 3.69Å; F171-L175 HydrophobicContact CZ-CD1 3.57Å; F171-L175 HydrophobicContact CZ-CD2 3.72Å; F171-L175 HydrophobicContact CZ-CG 3.68Å; F171-L175 PolarHBondContact O-N 3.39Å; A172-L175 PolarHBondContact O-N 3.08Å; I173-L175 PolarHBondContact O-N 3.12Å; L175-R177 VanDerWaalsContact C-N 3.26Å; L175-R177 PolarHBondContact O-N 2.93Å; L175-Y178 PolarHBondContact O-N 3.47Å; L175-D179 WeakPolarHBondContact O-CB 3.43Å; L175-D179 PolarHBondContact O-N 3.49Å; L175-L197 HydrophobicContact CD1-CD2 4.48Å
176	D	88.5	Confident	85.7	Confident	0 Å²	0	32.3 Å²	32.3	0%	0	18%	0.179	C	C	.	.	H	α-helix	trans	-58.2	-40.2	174.6	173.3	64.5	0	0	0	111.4	S114 I117 A172 I173 D179 I180 R187 L189	S114-D176 WeakPolarHBondContact CA-OD2 3.32Å; S114-D176 WeakPolarHBondContact CB-OD2 3.43Å; S114-D176 PolarHBondContact OG-OD1 2.64Å; S114-D176 PolarHBondContact OG-OD2 2.84Å; I117-D176 HydrophobicContact CD1-CB 3.81Å; A172-D176 PolarHBondContact O-N 3.1Å; I173-D176 PolarHBondContact O-N 3.32Å; D176-D179 PolarHBondContact O-N 3.49Å; D176-I180 WeakPolarHBondContact O-CD1 3.46Å; D176-I180 WeakPolarHBondContact O-CG1 3.23Å; D176-I180 PolarHBondContact O-N 3.15Å; D176-I180 VanDerWaalsContact O-N 3.1Å; D176-R187 IonicContact OD1-NH2 3.8Å; D176-L189 HydrophobicContact CB-CD2 3.84Å
177	R	85.8	Confident	85.2	Confident	16 Å²	16	37.4 Å²	37.4	6%	0.06	20%	0.198	C	C	.	.	H	α-helix	trans	-70.8	-37.7	178.9	-63.6	-71.6	160.3	-103.8	-15.4	112.6	I173 T174 L175 S181 I271 S351	I173-R177 HydrophobicContact CG2-CG 4.4Å; I173-R177 WeakPolarHBondContact O-CG 3.33Å; I173-R177 PolarHBondContact O-N 3.35Å; T174-R177 PolarHBondContact O-N 3.25Å; L175-R177 VanDerWaalsContact C-N 3.26Å; L175-R177 PolarHBondContact O-N 2.93Å; R177-S181 WeakPolarHBondContact O-CB 3.39Å; R177-S181 PolarHBondContact O-N 2.91Å; R177-S181 PolarHBondContact O-OG 3.49Å; R177-I271 HydrophobicContact CB-CD1 4.25Å; R177-S351 WeakPolarHBondContact CD-OG 3.21Å; R177-S351 VanDerWaalsContact CG-OG 3.31Å; R177-S351 WeakPolarHBondContact CG-OG 3.26Å; R177-S351 PolarHBondContact NE-OG 3.36Å
178	Y	85.5	Confident	84.9	Confident	65 Å²	65	41.4 Å²	41.4	26%	0.255	22%	0.218	S	C	.	.	H	α-helix	trans	-61.9	-48.3	173.8	-179.4	-95	0	0	0	110.9	T174 L175 I180 S181 V182 K270 I271	T174-Y178 WeakPolarHBondContact O-CB 3.36Å; T174-Y178 PolarHBondContact O-N 3.28Å; L175-Y178 PolarHBondContact O-N 3.47Å; Y178-I180 PolarHBondContact O-N 2.76Å; Y178-S181 PolarHBondContact O-N 3.14Å; Y178-V182 HydrophobicContact CD2-CB 4.27Å; Y178-V182 HydrophobicContact CD2-CG2 3.63Å; Y178-V182 HydrophobicContact CE1-CB 4.49Å; Y178-V182 HydrophobicContact CE2-CB 4.02Å; Y178-V182 HydrophobicContact CE2-CG1 4.13Å; Y178-V182 HydrophobicContact CE2-CG2 3.6Å; Y178-V182 HydrophobicContact CG-CG2 4.26Å; Y178-V182 WeakPolarHBondContact O-CB 3.49Å; Y178-V182 PolarHBondContact O-N 2.98Å; Y178-K270 HydrophobicContact CD2-CB 4.46Å; Y178-K270 HydrophobicContact CE2-CB 3.84Å; Y178-I271 HydrophobicContact CD2-CG1 4.02Å
179	D	86.1	Confident	84.6	Confident	7 Å²	7	41 Å²	41	4%	0.037	22%	0.216	C	C	.	.	H	α-helix	trans	-57.3	-49.7	178.4	-171.2	64.3	0	0	0	111.9	L175 D176 S181 K183 R187 I188 L189	L175-D179 WeakPolarHBondContact O-CB 3.43Å; L175-D179 PolarHBondContact O-N 3.49Å; D176-D179 PolarHBondContact O-N 3.49Å; D179-S181 PolarHBondContact O-N 3.43Å; D179-K183 CarbonylContact O-C 3.58Å; D179-K183 PolarHBondContact O-N 3.21Å; D179-R187 WeakPolarHBondContact OD1-CA 3.13Å; D179-R187 VanDerWaalsContact OD2-CB 3.26Å; D179-R187 WeakPolarHBondContact OD2-CB 3.48Å; D179-R187 WeakPolarHBondContact OD2-CG 3.26Å; D179-R187 IonicContact OD2-CZ 3.24Å; D179-R187 IonicContact OD2-NE 2.94Å; D179-R187 PolarHBondContact OD2-NE 3.22Å; D179-R187 IonicContact OD2-NH2 3.83Å; D179-I188 PolarHBondContact OD1-N 3.12Å; D179-L189 HydrophobicContact CB-CB 4.47Å
180	I	84.1	Confident	84.5	Confident	33 Å²	33	44.2 Å²	44.2	17%	0.169	24%	0.236	C	C	.	.	H	α-helix	trans	-66.7	-39.1	-179.4	-68.9	166	0	0	0	112.5	S114 D176 Y178	S114-I180 VanDerWaalsContact OG-CD1 3.31Å; S114-I180 WeakPolarHBondContact OG-CD1 3.23Å; D176-I180 WeakPolarHBondContact O-CD1 3.46Å; D176-I180 WeakPolarHBondContact O-CG1 3.23Å; D176-I180 PolarHBondContact O-N 3.15Å; D176-I180 VanDerWaalsContact O-N 3.1Å; Y178-I180 PolarHBondContact O-N 2.76Å
181	S	80.5	Confident	84.4	Confident	9 Å²	9	47.5 Å²	47.5	6%	0.063	25%	0.252	C	S	.	.	H	α-helix	trans	-84.7	-48	-171.3	-57.3	0	0	0	0	111.9	R177 Y178 D179 R278	R177-S181 WeakPolarHBondContact O-CB 3.39Å; R177-S181 PolarHBondContact O-N 2.91Å; R177-S181 PolarHBondContact O-OG 3.49Å; Y178-S181 PolarHBondContact O-N 3.14Å; D179-S181 PolarHBondContact O-N 3.43Å; S181-R278 PolarHBondContact O-NH2 3.21Å
182	V	80.7	Confident	84.4	Confident	42 Å²	42	47.9 Å²	47.9	26%	0.255	27%	0.269	S	S	.	.	H	α-helix	trans	-88	-42.1	-171.4	-174.7	0	0	0	0	111.4	Y178 P184 I271 A274	Y178-V182 HydrophobicContact CD2-CB 4.27Å; Y178-V182 HydrophobicContact CD2-CG2 3.63Å; Y178-V182 HydrophobicContact CE1-CB 4.49Å; Y178-V182 HydrophobicContact CE2-CB 4.02Å; Y178-V182 HydrophobicContact CE2-CG1 4.13Å; Y178-V182 HydrophobicContact CE2-CG2 3.6Å; Y178-V182 HydrophobicContact CG-CG2 4.26Å; Y178-V182 WeakPolarHBondContact O-CB 3.49Å; Y178-V182 PolarHBondContact O-N 2.98Å; V182-P184 VanDerWaalsContact O-CD 3.26Å; V182-P184 WeakPolarHBondContact O-CD 3.33Å; V182-I271 HydrophobicContact CG2-CG1 4.14Å; V182-A274 HydrophobicContact CB-CB 4.38Å; V182-A274 HydrophobicContact CG1-CB 4.4Å; V182-A274 HydrophobicContact CG2-CB 3.8Å
183	K	78.5	Confident	84.5	Confident	85 Å²	85	54.7 Å²	54.7	37%	0.37	29%	0.294	S	S	.	.			trans	-119.9	57.7	-174.5	-62.4	-175.4	179.6	-178.3	0	113.1	D179 A185 N186 I188	D179-K183 CarbonylContact O-C 3.58Å; D179-K183 PolarHBondContact O-N 3.21Å; K183-A185 PolarHBondContact O-N 3.42Å; K183-A185 VanDerWaalsContact O-N 3.13Å; K183-N186 CarbonylContact O-C 3.45Å; K183-N186 PolarHBondContact O-N 3.16Å; K183-I188 HydrophobicContact CD-CD1 4.07Å
184	P	76.3	Confident	84.5	Confident	68 Å²	68	54.7 Å²	54.7	44%	0.442	30%	0.295	S	S	.	.	S	Bend	trans	-64.7	-23.8	-173.8	30.6	-39.8	0	0	0	114.7	V182	V182-P184 VanDerWaalsContact O-CD 3.26Å; V182-P184 WeakPolarHBondContact O-CD 3.33Å
185	A	76.5	Confident	84.6	Confident	91 Å²	91	58 Å²	58	75%	0.752	32%	0.315	S	S	*	.	S	Bend	trans	-90.8	-26.9	-179.6	0	0	0	0	0	112.9	K183	K183-A185 PolarHBondContact O-N 3.42Å; K183-A185 VanDerWaalsContact O-N 3.13Å
186	N	82.7	Confident	84.8	Confident	126 Å²	126	62 Å²	62	67%	0.674	33%	0.333	S	S	*	.	S	Bend	trans	-122.6	61.8	-175.3	-63.6	-15.6	0	0	0	108.8	K183 I188	K183-N186 CarbonylContact O-C 3.45Å; K183-N186 PolarHBondContact O-N 3.16Å; N186-I188 PolarHBondContact O-N 3.44Å
187	R	81.6	Confident	84.9	Confident	108 Å²	108	63.9 Å²	63.9	41%	0.408	34%	0.343	S	S	.	.			trans	-66.6	120.3	-178.9	-69.5	-168.3	72	-172.5	4	110.1	D176 D179	D176-R187 IonicContact OD1-NH2 3.8Å; D179-R187 WeakPolarHBondContact OD1-CA 3.13Å; D179-R187 VanDerWaalsContact OD2-CB 3.26Å; D179-R187 WeakPolarHBondContact OD2-CB 3.48Å; D179-R187 WeakPolarHBondContact OD2-CG 3.26Å; D179-R187 IonicContact OD2-CZ 3.24Å; D179-R187 IonicContact OD2-NE 2.94Å; D179-R187 PolarHBondContact OD2-NE 3.22Å; D179-R187 IonicContact OD2-NH2 3.83Å
188	I	83	Confident	85.1	Confident	85 Å²	85	63.7 Å²	63.7	44%	0.436	34%	0.343	S	S	.	.			trans	-88.2	-34.4	-177	-60.6	174.4	0	0	0	110.4	D179 K183 N186 T190 R193	D179-I188 PolarHBondContact OD1-N 3.12Å; K183-I188 HydrophobicContact CD-CD1 4.07Å; N186-I188 PolarHBondContact O-N 3.44Å; I188-T190 PolarHBondContact O-N 3.49Å; I188-T190 VanDerWaalsContact O-N 3.07Å; I188-R193 WeakPolarHBondContact O-CD 3.36Å; I188-R193 PolarHBondContact O-NH1 3.42Å
189	L	85.2	Confident	85.4	Confident	24 Å²	24	64.1 Å²	64.1	13%	0.126	35%	0.353	C	S	.	.			trans	-83.9	81.6	-176.9	-164.3	66.6	0	0	0	110.2	V113 I117 D176 D179 A194 L197	V113-L189 HydrophobicContact CG1-CD2 3.72Å; V113-L189 HydrophobicContact CG1-CG 3.83Å; I117-L189 HydrophobicContact CD1-CD2 3.69Å; D176-L189 HydrophobicContact CB-CD2 3.84Å; D179-L189 HydrophobicContact CB-CB 4.47Å; L189-A194 HydrophobicContact CD1-CB 4.27Å; L189-A194 HydrophobicContact CG-CB 4.26Å; L189-L197 HydrophobicContact CD1-CD2 4.23Å
190	T	88.8	Confident	85.7	Confident	69 Å²	69	65.7 Å²	65.7	42%	0.423	36%	0.364	S	S	.	.			trans	-77.6	167.7	172.5	62.3	0	0	0	0	111	I188 G192 R193 A194	I188-T190 PolarHBondContact O-N 3.49Å; I188-T190 VanDerWaalsContact O-N 3.07Å; T190-G192 PolarHBondContact O-N 2.99Å; T190-R193 PolarHBondContact O-N 3.43Å; T190-R193 WeakPolarHBondContact OG1-CG 3.06Å; T190-A194 WeakPolarHBondContact O-CB 3.39Å; T190-A194 PolarHBondContact O-N 3.5Å
191	M	86.9	Confident	86	Confident	70 Å²	70	64.2 Å²	64.2	35%	0.345	36%	0.357	S	S	.	.	H	α-helix	trans	-58.5	-48.1	-179	-168.6	62.5	99	0	0	112.8	V113 I116 R193 A194 V195	V113-M191 HydrophobicContact CG2-CB 4.4Å; V113-M191 HydrophobicContact CG2-SD 4.03Å; I116-M191 HydrophobicContact CD1-CE 3.61Å; I116-M191 HydrophobicContact CD1-SD 3.42Å; I116-M191 WeakPolarHBondContact CD1-SD 3.5Å; I116-M191 HydrophobicContact CG1-CE 4.47Å; I116-M191 HydrophobicContact CG1-SD 4.49Å; M191-R193 VanDerWaalsContact C-N 3.35Å; M191-R193 PolarHBondContact O-N 3.41Å; M191-A194 WeakPolarHBondContact O-CB 3.12Å; M191-A194 PolarHBondContact O-N 3.12Å; M191-V195 WeakPolarHBondContact O-CG2 3.33Å; M191-V195 PolarHBondContact O-N 3.07Å
192	G	88.8	Confident	86.7	Confident	53 Å²	53	67.4 Å²	67.4	55%	0.546	37%	0.368	S	S	.	.	H	α-helix	trans	-61.3	-41.3	178	0	0	0	0	0	112.9	T190 V195 M196	T190-G192 PolarHBondContact O-N 2.99Å; G192-V195 PolarHBondContact O-N 3.34Å; G192-M196 WeakPolarHBondContact O-CB 3.01Å; G192-M196 PolarHBondContact O-N 3.49Å
193	R	91	Very high	87.3	Confident	142 Å²	142	69.4 Å²	69.4	54%	0.536	38%	0.376	S	S	.	.	H	α-helix	trans	-67.4	-35.9	175.6	-71.8	177.2	175.5	175	-1.7	112.4	I188 T190 M191 L197	I188-R193 WeakPolarHBondContact O-CD 3.36Å; I188-R193 PolarHBondContact O-NH1 3.42Å; T190-R193 PolarHBondContact O-N 3.43Å; T190-R193 WeakPolarHBondContact OG1-CG 3.06Å; M191-R193 VanDerWaalsContact C-N 3.35Å; M191-R193 PolarHBondContact O-N 3.41Å; R193-L197 VanDerWaalsContact O-CB 3.32Å; R193-L197 WeakPolarHBondContact O-CB 3.19Å; R193-L197 PolarHBondContact O-N 3.44Å
194	A	89.1	Confident	87.8	Confident	1 Å²	1	71.6 Å²	71.6	1%	0.008	39%	0.386	C	S	.	.	H	α-helix	trans	-66.3	-44.4	175.8	0	0	0	0	0	111.3	V113 L189 T190 M191 L197 M198	V113-A194 HydrophobicContact CB-CB 4.47Å; V113-A194 HydrophobicContact CG1-CB 3.64Å; V113-A194 HydrophobicContact CG2-CB 4.3Å; L189-A194 HydrophobicContact CD1-CB 4.27Å; L189-A194 HydrophobicContact CG-CB 4.26Å; T190-A194 WeakPolarHBondContact O-CB 3.39Å; T190-A194 PolarHBondContact O-N 3.5Å; M191-A194 WeakPolarHBondContact O-CB 3.12Å; M191-A194 PolarHBondContact O-N 3.12Å; A194-L197 WeakPolarHBondContact O-CB 3.13Å; A194-L197 PolarHBondContact O-N 3.04Å; A194-M198 VanDerWaalsContact O-CG 3.27Å; A194-M198 WeakPolarHBondContact O-CG 3.24Å; A194-M198 PolarHBondContact O-N 2.9Å
195	V	89.6	Confident	88.6	Confident	70 Å²	70	68.4 Å²	68.4	42%	0.424	37%	0.365	S	S	.	.	H	α-helix	trans	-61.9	-46.3	175.5	173.5	0	0	0	0	110.8	M191 G192 L197 M198 T199	M191-V195 WeakPolarHBondContact O-CG2 3.33Å; M191-V195 PolarHBondContact O-N 3.07Å; G192-V195 PolarHBondContact O-N 3.34Å; V195-L197 VanDerWaalsContact C-N 3.31Å; V195-L197 PolarHBondContact O-N 2.92Å; V195-M198 WeakPolarHBondContact O-CB 3.3Å; V195-M198 PolarHBondContact O-N 2.85Å; V195-T199 PolarHBondContact O-N 3.31Å; V195-T199 PolarHBondContact O-OG1 3.16Å; V195-T199 VanDerWaalsContact O-OG1 3.13Å
196	M	91.2	Very high	89.3	Confident	137 Å²	137	69.5 Å²	69.5	68%	0.675	35%	0.353	S	S	*	.	H	α-helix	trans	-58.4	-41.9	175.2	-175.8	-171.1	-65.2	0	0	112.3	G192 T199 S200	G192-M196 WeakPolarHBondContact O-CB 3.01Å; G192-M196 PolarHBondContact O-N 3.49Å; M196-T199 PolarHBondContact O-N 3Å; M196-S200 PolarHBondContact O-N 3Å
197	L	90.8	Very high	89.6	Confident	40 Å²	40	69.3 Å²	69.3	21%	0.209	35%	0.346	C	S	.	.	H	α-helix	trans	-61	-43.3	173.1	177.4	66.4	0	0	0	111	A172 L175 L189 R193 A194 V195 S200 I201	A172-L197 HydrophobicContact CB-CD2 4.09Å; L175-L197 HydrophobicContact CD1-CD2 4.48Å; L189-L197 HydrophobicContact CD1-CD2 4.23Å; R193-L197 VanDerWaalsContact O-CB 3.32Å; R193-L197 WeakPolarHBondContact O-CB 3.19Å; R193-L197 PolarHBondContact O-N 3.44Å; A194-L197 WeakPolarHBondContact O-CB 3.13Å; A194-L197 PolarHBondContact O-N 3.04Å; V195-L197 VanDerWaalsContact C-N 3.31Å; V195-L197 PolarHBondContact O-N 2.92Å; L197-S200 PolarHBondContact O-N 3.28Å; L197-S200 PolarHBondContact O-OG 3.33Å; L197-I201 HydrophobicContact CD1-CD1 4.37Å; L197-I201 HydrophobicContact CG-CD1 4.03Å; L197-I201 WeakPolarHBondContact O-CD1 3.31Å; L197-I201 WeakPolarHBondContact O-CG1 3.31Å; L197-I201 PolarHBondContact O-N 3.12Å
198	M	90.4	Very high	89.9	Confident	12 Å²	12	64.6 Å²	64.6	6%	0.059	33%	0.33	C	S	.	.	H	α-helix	trans	-63.9	-44.2	177.4	-60.8	-40.4	-55.7	0	0	111.7	I117 N120 A194 V195 S200 I201 W202	I117-M198 HydrophobicContact CG1-SD 4.03Å; N120-M198 HydrophobicContact CB-CE 3.37Å; N120-M198 WeakPolarHBondContact ND2-CE 3.4Å; A194-M198 VanDerWaalsContact O-CG 3.27Å; A194-M198 WeakPolarHBondContact O-CG 3.24Å; A194-M198 PolarHBondContact O-N 2.9Å; V195-M198 WeakPolarHBondContact O-CB 3.3Å; V195-M198 PolarHBondContact O-N 2.85Å; M198-S200 VanDerWaalsContact C-N 3.31Å; M198-S200 PolarHBondContact O-N 3.28Å; M198-I201 HydrophobicContact CE-CD1 3.88Å; M198-I201 WeakPolarHBondContact O-CB 3.19Å; M198-I201 PolarHBondContact O-N 3.37Å; M198-I201 HydrophobicContact SD-CD1 3.99Å; M198-W202 PolarHBondContact O-N 3.29Å; M198-W202 VanDerWaalsContact O-N 3.1Å
199	T	91.3	Very high	90.2	Very high	75 Å²	75	62.5 Å²	62.5	46%	0.46	32%	0.318	S	S	.	.	H	α-helix	trans	-59.5	-43.3	176.2	-54.6	0	0	0	0	111.3	V195 M196 I201 W202 I203	V195-T199 PolarHBondContact O-N 3.31Å; V195-T199 PolarHBondContact O-OG1 3.16Å; V195-T199 VanDerWaalsContact O-OG1 3.13Å; M196-T199 PolarHBondContact O-N 3Å; T199-I201 VanDerWaalsContact C-N 3.34Å; T199-I201 PolarHBondContact O-N 2.96Å; T199-W202 PolarHBondContact O-N 3.12Å; T199-I203 HydrophobicContact CG2-CD1 4.07Å; T199-I203 WeakPolarHBondContact O-CG1 3.17Å; T199-I203 PolarHBondContact O-N 2.86Å; T199-I203 VanDerWaalsContact O-N 3.11Å
200	S	92.1	Very high	90.3	Very high	39 Å²	39	63.2 Å²	63.2	27%	0.273	32%	0.322	S	S	.	.	H	α-helix	trans	-65.4	-37.9	176.9	71.5	0	0	0	0	112.2	M196 L197 M198 W202 I203 F204	M196-S200 PolarHBondContact O-N 3Å; L197-S200 PolarHBondContact O-N 3.28Å; L197-S200 PolarHBondContact O-OG 3.33Å; M198-S200 VanDerWaalsContact C-N 3.31Å; M198-S200 PolarHBondContact O-N 3.28Å; S200-W202 PolarHBondContact O-N 2.94Å; S200-I203 PolarHBondContact O-N 2.69Å; S200-F204 WeakPolarHBondContact O-CD2 3.5Å; S200-F204 PolarHBondContact O-N 3.41Å
201	I	91.9	Very high	90	Very high	2 Å²	2	61.8 Å²	61.8	1%	0.01	31%	0.311	C	S	.	.	H	α-helix	trans	-55.9	-50.5	174.5	-69.3	168	0	0	0	110.7	I168 N169 A172 L197 M198 T199 I203 F204 S205	I168-I201 HydrophobicContact CB-CG2 4.39Å; I168-I201 HydrophobicContact CG2-CB 4.47Å; I168-I201 HydrophobicContact CG2-CD1 4.17Å; I168-I201 HydrophobicContact CG2-CG1 3.61Å; I168-I201 HydrophobicContact CG2-CG2 4.34Å; N169-I201 WeakPolarHBondContact ND2-CG2 3.39Å; A172-I201 HydrophobicContact CB-CD1 3.77Å; L197-I201 HydrophobicContact CD1-CD1 4.37Å; L197-I201 HydrophobicContact CG-CD1 4.03Å; L197-I201 WeakPolarHBondContact O-CD1 3.31Å; L197-I201 WeakPolarHBondContact O-CG1 3.31Å; L197-I201 PolarHBondContact O-N 3.12Å; M198-I201 HydrophobicContact CE-CD1 3.88Å; M198-I201 WeakPolarHBondContact O-CB 3.19Å; M198-I201 PolarHBondContact O-N 3.37Å; M198-I201 HydrophobicContact SD-CD1 3.99Å; T199-I201 VanDerWaalsContact C-N 3.34Å; T199-I201 PolarHBondContact O-N 2.96Å; I201-I203 VanDerWaalsContact C-N 3.31Å; I201-I203 PolarHBondContact O-N 3.44Å; I201-F204 PolarHBondContact O-N 3.01Å; I201-S205 WeakPolarHBondContact O-CB 3.44Å; I201-S205 PolarHBondContact O-N 2.83Å; I201-S205 PolarHBondContact O-OG 2.84Å; I201-S205 VanDerWaalsContact O-OG 3.05Å
202	W	94.7	Very high	89.6	Confident	77 Å²	77	58.7 Å²	58.7	29%	0.292	30%	0.296	S	S	.	.	H	α-helix	trans	-62.2	-38.3	179.3	-73.3	108.2	0	0	0	112.8	N120 V123 L127 F161 M198 T199 S200 S205 F206	N120-W202 WeakPolarHBondContact OD1-CZ2 3.34Å; N120-W202 PolarHBondContact OD1-NE1 3.43Å; V123-W202 HydrophobicContact CG1-CH2 4.22Å; V123-W202 HydrophobicContact CG1-CZ2 4.14Å; L127-W202 HydrophobicContact CD1-CH2 3.47Å; L127-W202 VanDerWaalsContact CD1-CH2 3.47Å; L127-W202 HydrophobicContact CD1-CZ3 3.55Å; F161-W202 HydrophobicContact CZ-CZ3 4.07Å; M198-W202 PolarHBondContact O-N 3.29Å; M198-W202 VanDerWaalsContact O-N 3.1Å; T199-W202 PolarHBondContact O-N 3.12Å; S200-W202 PolarHBondContact O-N 2.94Å; W202-S205 PolarHBondContact O-N 3.12Å; W202-F206 WeakPolarHBondContact O-CB 3.15Å; W202-F206 PolarHBondContact O-N 2.97Å
203	I	93.6	Very high	89.2	Confident	84 Å²	84	57.2 Å²	57.2	43%	0.431	28%	0.275	S	S	.	.	H	α-helix	trans	-63.4	-49.4	175.7	-68.6	167.3	0	0	0	110.7	T199 S200 I201 S205 F206 F207	T199-I203 HydrophobicContact CG2-CD1 4.07Å; T199-I203 WeakPolarHBondContact O-CG1 3.17Å; T199-I203 PolarHBondContact O-N 2.86Å; T199-I203 VanDerWaalsContact O-N 3.11Å; S200-I203 PolarHBondContact O-N 2.69Å; I201-I203 VanDerWaalsContact C-N 3.31Å; I201-I203 PolarHBondContact O-N 3.44Å; I203-S205 VanDerWaalsContact C-N 3.33Å; I203-S205 PolarHBondContact O-N 3.19Å; I203-F206 PolarHBondContact O-N 2.87Å; I203-F207 HydrophobicContact CG2-CD2 3.68Å; I203-F207 HydrophobicContact CG2-CE2 3.36Å; I203-F207 WeakPolarHBondContact O-CD2 3.04Å; I203-F207 PolarHBondContact O-N 3.28Å
204	F	89.1	Confident	88.5	Confident	131 Å²	131	55.5 Å²	55.5	58%	0.575	28%	0.275	S	S	*	.	H	α-helix	trans	-61.9	-40.7	177.5	-85	-71.5	0	0	0	112.4	I168 S200 I201 F207 S208	I168-F204 HydrophobicContact CD1-CB 4.09Å; S200-F204 WeakPolarHBondContact O-CD2 3.5Å; S200-F204 PolarHBondContact O-N 3.41Å; I201-F204 PolarHBondContact O-N 3.01Å; F204-F207 PolarHBondContact O-N 3.41Å; F204-S208 PolarHBondContact O-N 2.79Å
205	S	92.3	Very high	87.6	Confident	0 Å²	0	57.8 Å²	57.8	0%	0	29%	0.285	C	S	.	.	H	α-helix	trans	-60	-44.5	174.1	-72.8	0	0	0	0	112.5	S165 I201 W202 I203 S208 F209	S165-S205 WeakPolarHBondContact CA-OG 3.48Å; S165-S205 WeakPolarHBondContact CB-OG 3.47Å; S165-S205 WeakPolarHBondContact OG-CB 3.47Å; S165-S205 PolarHBondContact OG-OG 3.49Å; I201-S205 WeakPolarHBondContact O-CB 3.44Å; I201-S205 PolarHBondContact O-N 2.83Å; I201-S205 PolarHBondContact O-OG 2.84Å; I201-S205 VanDerWaalsContact O-OG 3.05Å; W202-S205 PolarHBondContact O-N 3.12Å; I203-S205 VanDerWaalsContact C-N 3.33Å; I203-S205 PolarHBondContact O-N 3.19Å; S205-S208 WeakPolarHBondContact O-CB 3.23Å; S205-S208 PolarHBondContact O-N 3.22Å; S205-F209 PolarHBondContact O-N 3.39Å
206	F	91.4	Very high	86.4	Confident	114 Å²	114	57.4 Å²	57.4	50%	0.5	28%	0.283	S	S	.	.	H	α-helix	trans	-64.7	-42.9	176.8	178.2	-105.4	0	0	0	111.7	W202 I203 S208 F209 L210	W202-F206 WeakPolarHBondContact O-CB 3.15Å; W202-F206 PolarHBondContact O-N 2.97Å; I203-F206 PolarHBondContact O-N 2.87Å; F206-S208 VanDerWaalsContact C-N 3.28Å; F206-S208 PolarHBondContact O-N 3.15Å; F206-F209 VanDerWaalsContact O-CB 3.28Å; F206-F209 WeakPolarHBondContact O-CB 3.46Å; F206-F209 PolarHBondContact O-N 3.02Å; F206-L210 HydrophobicContact CD1-CD1 4.11Å; F206-L210 HydrophobicContact CE1-CD1 3.54Å; F206-L210 HydrophobicContact CE1-CD2 4.47Å; F206-L210 HydrophobicContact CE1-CG 4.11Å; F206-L210 HydrophobicContact CE2-CD2 4.38Å; F206-L210 HydrophobicContact CZ-CD1 3.93Å; F206-L210 HydrophobicContact CZ-CD2 4.02Å; F206-L210 HydrophobicContact CZ-CG 4.14Å; F206-L210 PolarHBondContact O-N 2.98Å; F206-L210 VanDerWaalsContact O-N 3.16Å
207	F	89.1	Confident	85.2	Confident	122 Å²	122	55.9 Å²	55.9	54%	0.535	28%	0.278	S	S	.	.	H	α-helix	trans	-59.8	-40.8	173.4	-77.9	-61.6	0	0	0	112.1	I203 F204 F209 L210 I211	I203-F207 HydrophobicContact CG2-CD2 3.68Å; I203-F207 HydrophobicContact CG2-CE2 3.36Å; I203-F207 WeakPolarHBondContact O-CD2 3.04Å; I203-F207 PolarHBondContact O-N 3.28Å; F204-F207 PolarHBondContact O-N 3.41Å; F207-F209 PolarHBondContact O-N 3.48Å; F207-L210 HydrophobicContact CD1-CD1 4.47Å; F207-L210 PolarHBondContact O-N 2.88Å; F207-L210 VanDerWaalsContact O-N 3.09Å; F207-I211 WeakPolarHBondContact O-CG1 3.43Å; F207-I211 PolarHBondContact O-N 3.44Å
208	S	87.3	Confident	83.9	Confident	10 Å²	10	58.5 Å²	58.5	7%	0.07	29%	0.288	C	S	.	.	H	α-helix	trans	-62	-31.8	174.9	-176.3	0	0	0	0	113.2	V164 F204 S205 F206 L210	V164-S208 VanDerWaalsContact CG2-OG 3.22Å; V164-S208 WeakPolarHBondContact CG2-OG 3.1Å; F204-S208 PolarHBondContact O-N 2.79Å; S205-S208 WeakPolarHBondContact O-CB 3.23Å; S205-S208 PolarHBondContact O-N 3.22Å; F206-S208 VanDerWaalsContact C-N 3.28Å; F206-S208 PolarHBondContact O-N 3.15Å; S208-L210 VanDerWaalsContact C-N 3.34Å
209	F	89.6	Confident	82.5	Confident	40 Å²	40	64.2 Å²	64.2	18%	0.175	31%	0.313	C	S	.	.	H	α-helix	trans	-67.8	-34.7	174.4	-179.6	-92.6	0	0	0	111.8	F154 A157 F161 S205 F206 F207 I211 P212 F213	F154-F209 AromaticContact CD2-CZ 3.95Å; F154-F209 HydrophobicContact CD2-CZ 3.95Å; F154-F209 HydrophobicContact CE2-CE1 4.45Å; F154-F209 HydrophobicContact CE2-CE2 4.41Å; F154-F209 AromaticContact CE2-CZ 3.57Å; F154-F209 HydrophobicContact CE2-CZ 3.57Å; F154-F209 HydrophobicContact CZ-CZ 4.03Å; A157-F209 VanDerWaalsContact C-CD2 3.49Å; A157-F209 HydrophobicContact CB-CD1 4.44Å; A157-F209 HydrophobicContact CB-CD2 3.71Å; A157-F209 HydrophobicContact CB-CE1 4.3Å; A157-F209 HydrophobicContact CB-CE2 3.53Å; A157-F209 HydrophobicContact CB-CG 4.16Å; A157-F209 HydrophobicContact CB-CZ 3.85Å; A157-F209 VanDerWaalsContact CB-O 3.22Å; A157-F209 WeakPolarHBondContact CB-O 3.42Å; A157-F209 WeakPolarHBondContact O-CD2 3.46Å; F161-F209 HydrophobicContact CB-CB 4.1Å; F161-F209 HydrophobicContact CB-CD2 3.93Å; F161-F209 HydrophobicContact CD2-CB 4.42Å; S205-F209 PolarHBondContact O-N 3.39Å; F206-F209 VanDerWaalsContact O-CB 3.28Å; F206-F209 WeakPolarHBondContact O-CB 3.46Å; F206-F209 PolarHBondContact O-N 3.02Å; F207-F209 PolarHBondContact O-N 3.48Å; F209-I211 VanDerWaalsContact C-N 3.33Å; F209-I211 PolarHBondContact O-N 3.03Å; F209-P212 WeakPolarHBondContact O-CD 3.31Å; F209-F213 HydrophobicContact CD1-CE2 4.21Å; F209-F213 HydrophobicContact CE1-CD2 4.41Å; F209-F213 AromaticContact CE1-CE2 3.6Å; F209-F213 HydrophobicContact CE1-CE2 3.6Å; F209-F213 HydrophobicContact CE1-CZ 4.34Å; F209-F213 AromaticContact CZ-CE2 3.9Å; F209-F213 HydrophobicContact CZ-CE2 3.9Å; F209-F213 HydrophobicContact CZ-CZ 4.39Å
210	L	87.4	Confident	80.8	Confident	40 Å²	40	63.2 Å²	63.2	21%	0.209	31%	0.308	C	S	.	.	H	α-helix	trans	-74.9	-20.2	-178.4	-64.9	-179.4	0	0	0	114	F206 F207 S208 F213 I214	F206-L210 HydrophobicContact CD1-CD1 4.11Å; F206-L210 HydrophobicContact CE1-CD1 3.54Å; F206-L210 HydrophobicContact CE1-CD2 4.47Å; F206-L210 HydrophobicContact CE1-CG 4.11Å; F206-L210 HydrophobicContact CE2-CD2 4.38Å; F206-L210 HydrophobicContact CZ-CD1 3.93Å; F206-L210 HydrophobicContact CZ-CD2 4.02Å; F206-L210 HydrophobicContact CZ-CG 4.14Å; F206-L210 PolarHBondContact O-N 2.98Å; F206-L210 VanDerWaalsContact O-N 3.16Å; F207-L210 HydrophobicContact CD1-CD1 4.47Å; F207-L210 PolarHBondContact O-N 2.88Å; F207-L210 VanDerWaalsContact O-N 3.09Å; S208-L210 VanDerWaalsContact C-N 3.34Å; L210-F213 WeakPolarHBondContact O-CB 3.02Å; L210-F213 PolarHBondContact O-N 2.96Å; L210-F213 VanDerWaalsContact O-N 3.1Å; L210-I214 HydrophobicContact CB-CD1 4.37Å; L210-I214 WeakPolarHBondContact O-CG1 3.42Å; L210-I214 PolarHBondContact O-N 2.87Å; L210-I214 VanDerWaalsContact O-N 3.13Å
211	I	82.1	Confident	78.7	Confident	39 Å²	39	69.9 Å²	69.9	20%	0.2	34%	0.34	C	S	.	.	H	α-helix	trans	-53.2	-51.9	-173.9	-69.4	171.6	0	0	0	112.2	F207 F209 F213 I214 E215 H249 V252	F207-I211 WeakPolarHBondContact O-CG1 3.43Å; F207-I211 PolarHBondContact O-N 3.44Å; F209-I211 VanDerWaalsContact C-N 3.33Å; F209-I211 PolarHBondContact O-N 3.03Å; I211-F213 VanDerWaalsContact C-N 3.26Å; I211-F213 PolarHBondContact O-N 2.78Å; I211-I214 PolarHBondContact O-N 3.19Å; I211-I214 VanDerWaalsContact O-N 3.12Å; I211-E215 HydrophobicContact CG2-CG 4.45Å; I211-E215 WeakPolarHBondContact CG2-OE1 2.9Å; I211-E215 WeakPolarHBondContact O-CG 3.19Å; I211-E215 PolarHBondContact O-N 2.81Å; I211-H249 HydrophobicContact CG2-CB 3.85Å; I211-V252 HydrophobicContact CD1-CB 4.45Å; I211-V252 HydrophobicContact CD1-CG1 3.84Å
212	P	79.6	Confident	76.5	Confident	5 Å²	5	78.1 Å²	78.1	3%	0.032	38%	0.378	C	S	.	.	H	α-helix	trans	-61.7	-30	-179.6	-28.2	40.5	0	0	0	114.2	E156 A157 F209 E215 V216 H249	E156-P212 HydrophobicContact CB-CB 4.38Å; E156-P212 HydrophobicContact CB-CG 4.36Å; A157-P212 HydrophobicContact CB-CB 4.46Å; A157-P212 HydrophobicContact CB-CG 4.24Å; F209-P212 WeakPolarHBondContact O-CD 3.31Å; P212-E215 PolarHBondContact O-N 3.19Å; P212-V216 WeakPolarHBondContact O-CG2 3.14Å; P212-V216 PolarHBondContact O-N 3.35Å; P212-H249 HydrophobicContact CG-CB 4.41Å
213	F	79.5	Confident	74.2	Confident	22 Å²	22	80.8 Å²	80.8	10%	0.096	41%	0.409	C	S	.	.	H	α-helix	trans	-71.7	-38	176.1	-65.7	-81.5	0	0	0	112.4	F154 A157 F209 L210 I211 E215 F218 F219	F154-F213 HydrophobicContact CB-CZ 4.4Å; F154-F213 AromaticContact CD2-CZ 3.88Å; F154-F213 HydrophobicContact CD2-CZ 3.88Å; A157-F213 HydrophobicContact CB-CD2 4.15Å; A157-F213 HydrophobicContact CB-CE2 3.42Å; A157-F213 VanDerWaalsContact CB-CE2 3.42Å; A157-F213 HydrophobicContact CB-CZ 4.14Å; F209-F213 HydrophobicContact CD1-CE2 4.21Å; F209-F213 HydrophobicContact CE1-CD2 4.41Å; F209-F213 AromaticContact CE1-CE2 3.6Å; F209-F213 HydrophobicContact CE1-CE2 3.6Å; F209-F213 HydrophobicContact CE1-CZ 4.34Å; F209-F213 AromaticContact CZ-CE2 3.9Å; F209-F213 HydrophobicContact CZ-CE2 3.9Å; F209-F213 HydrophobicContact CZ-CZ 4.39Å; L210-F213 WeakPolarHBondContact O-CB 3.02Å; L210-F213 PolarHBondContact O-N 2.96Å; L210-F213 VanDerWaalsContact O-N 3.1Å; I211-F213 VanDerWaalsContact C-N 3.26Å; I211-F213 PolarHBondContact O-N 2.78Å; F213-E215 VanDerWaalsContact C-N 3.29Å; F213-F218 HydrophobicContact CB-CB 4.27Å; F213-F218 HydrophobicContact CD1-CD1 4.42Å; F213-F218 HydrophobicContact CD1-CG 4.24Å; F213-F218 WeakPolarHBondContact O-CB 3.32Å; F213-F218 PolarHBondContact O-N 3.19Å; F213-F219 HydrophobicContact CB-CE2 3.89Å; F213-F219 HydrophobicContact CB-CZ 4.42Å
214	I	77.1	Confident	71.8	Confident	105 Å²	105	79.5 Å²	79.5	54%	0.538	42%	0.416	S	S	.	.	H	α-helix	trans	-65.3	-38.4	175.1	-62.9	167.8	0	0	0	109.7	L210 I211 N217 F219	L210-I214 HydrophobicContact CB-CD1 4.37Å; L210-I214 WeakPolarHBondContact O-CG1 3.42Å; L210-I214 PolarHBondContact O-N 2.87Å; L210-I214 VanDerWaalsContact O-N 3.13Å; I211-I214 PolarHBondContact O-N 3.19Å; I211-I214 VanDerWaalsContact O-N 3.12Å; I214-N217 WeakPolarHBondContact O-CA 3.49Å; I214-N217 PolarHBondContact O-N 3.44Å; I214-N217 VanDerWaalsContact O-N 3.08Å; I214-F219 HydrophobicContact CG1-CD2 4.42Å; I214-F219 HydrophobicContact CG1-CE2 4.31Å
215	E	68.6	Low	69.8	Low	49 Å²	49	81 Å²	81	23%	0.229	43%	0.43	C	S	.	.	H	α-helix	trans	-64.7	-40.9	179.8	-74.9	172.8	-170.1	0	0	113.7	I211 P212 F213 N217 Y248 H249	I211-E215 HydrophobicContact CG2-CG 4.45Å; I211-E215 WeakPolarHBondContact CG2-OE1 2.9Å; I211-E215 WeakPolarHBondContact O-CG 3.19Å; I211-E215 PolarHBondContact O-N 2.81Å; P212-E215 PolarHBondContact O-N 3.19Å; F213-E215 VanDerWaalsContact C-N 3.29Å; E215-N217 PolarHBondContact O-N 2.92Å; E215-N217 VanDerWaalsContact O-N 3.15Å; E215-Y248 WeakPolarHBondContact OE1-CB 3.39Å; E215-H249 VanDerWaalsContact OE1-CA 3.24Å; E215-H249 WeakPolarHBondContact OE1-CA 3.48Å; E215-H249 WeakPolarHBondContact OE1-CB 3.45Å; E215-H249 PolarHBondContact OE1-N 2.96Å; E215-H249 WeakPolarHBondContact OE2-CB 3.13Å; E215-H249 IonicContact OE2-CG 2.74Å; E215-H249 PolarHBondContact OE2-N 2.9Å; E215-H249 IonicContact OE2-ND1 3.57Å; E215-H249 PolarHBondContact OE2-ND1 3.45Å
216	V	64.4	Low	67.4	Low	63 Å²	63	86.3 Å²	86.3	38%	0.382	46%	0.463	S	S	.	.	T	Hydrogen-bonded Turn	trans	-77.1	6.6	176.8	-175.7	0	0	0	0	111.3	P212 F218	P212-V216 WeakPolarHBondContact O-CG2 3.14Å; P212-V216 PolarHBondContact O-N 3.35Å; V216-F218 PolarHBondContact O-N 2.69Å
217	N	66.4	Low	65.4	Low	104 Å²	104	89.2 Å²	89.2	56%	0.556	47%	0.471	S	S	*	.	T	Hydrogen-bonded Turn	trans	52.5	33	-175.5	-141.1	35	0	0	0	112.2	I214 E215 F219 S220	I214-N217 WeakPolarHBondContact O-CA 3.49Å; I214-N217 PolarHBondContact O-N 3.44Å; I214-N217 VanDerWaalsContact O-N 3.08Å; E215-N217 PolarHBondContact O-N 2.92Å; E215-N217 VanDerWaalsContact O-N 3.15Å; N217-F219 PolarHBondContact O-N 3.37Å; N217-S220 WeakPolarHBondContact ND2-CB 3.46Å; N217-S220 PolarHBondContact ND2-OG 3.32Å; N217-S220 PolarHBondContact O-N 3.38Å; N217-S220 PolarHBondContact O-OG 2.89Å
218	F	63.3	Low	63.5	Low	96 Å²	96	89.2 Å²	89.2	42%	0.421	47%	0.472	S	S	.	.	T	Hydrogen-bonded Turn	trans	-55.6	-31.3	-173.7	-177.7	-95.4	0	0	0	112.7	L150 F213 V216	L150-F218 HydrophobicContact CD2-CD2 4.32Å; L150-F218 HydrophobicContact CD2-CE2 3.73Å; F213-F218 HydrophobicContact CB-CB 4.27Å; F213-F218 HydrophobicContact CD1-CD1 4.42Å; F213-F218 HydrophobicContact CD1-CG 4.24Å; F213-F218 WeakPolarHBondContact O-CB 3.32Å; F213-F218 PolarHBondContact O-N 3.19Å; V216-F218 PolarHBondContact O-N 2.69Å
219	F	61.8	Low	61.6	Low	132 Å²	132	90.9 Å²	90.9	58%	0.579	48%	0.481	S	S	*	.	T	Hydrogen-bonded Turn	trans	-86.6	-5.8	-178.8	-60.2	-73.7	0	0	0	114.2	F213 I214 N217 L221	F213-F219 HydrophobicContact CB-CE2 3.89Å; F213-F219 HydrophobicContact CB-CZ 4.42Å; I214-F219 HydrophobicContact CG1-CD2 4.42Å; I214-F219 HydrophobicContact CG1-CE2 4.31Å; N217-F219 PolarHBondContact O-N 3.37Å; F219-L221 PolarHBondContact O-N 3.1Å
220	S	54.8	Low	59.7	Low	53 Å²	53	93.7 Å²	93.7	37%	0.371	49%	0.493	S	S	.	.			trans	-81.5	108.3	174.1	76.1	0	0	0	0	110	N217 Q222	N217-S220 WeakPolarHBondContact ND2-CB 3.46Å; N217-S220 PolarHBondContact ND2-OG 3.32Å; N217-S220 PolarHBondContact O-N 3.38Å; N217-S220 PolarHBondContact O-OG 2.89Å; S220-Q222 VanDerWaalsContact C-N 3.3Å; S220-Q222 PolarHBondContact O-N 3.2Å
221	L	48.9	Very low	57.8	Low	179 Å²	179	92.4 Å²	92.4	94%	0.937	49%	0.486	S	S	*	.			trans	-63.5	86.8	164.9	-84.2	133.9	0	0	0	109.5	F219	F219-L221 PolarHBondContact O-N 3.1Å
222	Q	45.6	Very low	56.1	Low	175 Å²	175	91.6 Å²	91.6	82%	0.818	48%	0.483	S	S	*	.			trans	-128.3	123.4	166.8	-157.1	119.5	1.5	0	0	110.9	S220 G224	S220-Q222 VanDerWaalsContact C-N 3.3Å; S220-Q222 PolarHBondContact O-N 3.2Å; Q222-G224 PolarHBondContact O-N 3.29Å
223	S	45.9	Very low	54.7	Low	133 Å²	133	91.7 Å²	91.7	93%	0.93	48%	0.483	S	S	*	.			trans	-70.3	93.6	-170.4	-174.9	0	0	0	0	113.2
224	G	43.2	Very low	53.3	Low	57 Å²	57	91 Å²	91	59%	0.588	48%	0.481	S	S	*	.			trans	-170	106.9	169.4	0	0	0	0	0	111.1	Q222 T226	Q222-G224 PolarHBondContact O-N 3.29Å; G224-T226 VanDerWaalsContact C-N 3.32Å; G224-T226 PolarHBondContact O-N 3.17Å
225	N	46.9	Very low	51.8	Low	162 Å²	162	87.4 Å²	87.4	87%	0.866	46%	0.464	S	S	*	.			trans	-67.9	79.9	-179.7	-74.4	-13.5	0	0	0	112
226	T	43.7	Very low	50.4	Low	112 Å²	112	89.4 Å²	89.4	69%	0.687	48%	0.483	S	S	*	.			trans	-152.7	101.4	155	46.5	0	0	0	0	108.7	G224 E228	G224-T226 VanDerWaalsContact C-N 3.32Å; G224-T226 PolarHBondContact O-N 3.17Å; T226-E228 PolarHBondContact O-N 3.42Å
227	W	48.7	Very low	49.4	Very low	175 Å²	175	90.6 Å²	90.6	66%	0.663	49%	0.49	S	S	*	.			trans	-67	96.9	170.2	-54.8	97.2	0	0	0	108.6	N229	W227-N229 PolarHBondContact O-N 3.09Å
228	E	49.2	Very low	48	Very low	122 Å²	122	90.8 Å²	90.8	57%	0.57	50%	0.5	S	S	*	.			trans	-75.3	120.7	174.1	-70.7	-177	160.6	0	0	109.8	T226 K230	T226-E228 PolarHBondContact O-N 3.42Å; E228-K230 HydrophobicContact CB-CD 4.47Å; E228-K230 HydrophobicContact CB-CG 4.32Å; E228-K230 PolarHBondContact O-N 3.04Å; E228-K230 WeakPolarHBondContact OE2-CE 3.17Å; E228-K230 IonicContact OE2-NZ 2.7Å; E228-K230 PolarHBondContact OE2-NZ 3.17Å
229	N	48.2	Very low	46.9	Very low	46 Å²	46	91.1 Å²	91.1	25%	0.246	50%	0.503	C	S	.	.			trans	-64.5	91.3	177.1	-75.2	-40.9	0	0	0	111	A149 W227 C234 V235	A149-N229 WeakPolarHBondContact CA-OD1 3.49Å; A149-N229 WeakPolarHBondContact CB-OD1 3.38Å; W227-N229 PolarHBondContact O-N 3.09Å; N229-C234 HydrophobicContact CB-CB 4.44Å; N229-C234 VanDerWaalsContact CB-O 3.31Å; N229-C234 WeakPolarHBondContact CB-O 3.43Å; N229-V235 WeakPolarHBondContact O-CG2 3.3Å
230	K	47.8	Very low	45.9	Very low	99 Å²	99	90.1 Å²	90.1	43%	0.43	50%	0.496	S	S	.	.			trans	-109.2	44.8	-177.6	-69.2	176.7	178.2	162.8	0	112.6	E228	E228-K230 HydrophobicContact CB-CD 4.47Å; E228-K230 HydrophobicContact CB-CG 4.32Å; E228-K230 PolarHBondContact O-N 3.04Å; E228-K230 WeakPolarHBondContact OE2-CE 3.17Å; E228-K230 IonicContact OE2-NZ 2.7Å; E228-K230 PolarHBondContact OE2-NZ 3.17Å
231	T	47.4	Very low	45.1	Very low	12 Å²	12	94.6 Å²	94.6	7%	0.074	51%	0.505	C	S	.	.	S	Bend	trans	-128.9	140	177.3	-26.8	0	0	0	0	109.7	C152 E156 L233 C234 V235 M246	C152-T231 HydrophobicContact CB-CG2 4.19Å; E156-T231 HydrophobicContact CB-CG2 4.37Å; E156-T231 HydrophobicContact CG-CG2 3.46Å; E156-T231 VanDerWaalsContact CG-CG2 3.46Å; T231-L233 PolarHBondContact O-N 3.45Å; T231-C234 WeakPolarHBondContact O-CA 3.32Å; T231-C234 PolarHBondContact O-N 3.18Å; T231-V235 WeakPolarHBondContact O-CG2 3.14Å; T231-V235 PolarHBondContact O-N 3.38Å; T231-M246 VanDerWaalsContact C-CE 3.49Å
232	L	47.5	Very low	44.8	Very low	23 Å²	23	91.2 Å²	91.2	12%	0.12	49%	0.493	C	S	.	.	T	Hydrogen-bonded Turn	trans	-51.8	-28.8	-169.1	-165.5	88.9	0	0	0	114.1	M246 I372 P377	L232-M246 HydrophobicContact CB-CE 3.88Å; L232-M246 HydrophobicContact CD1-CE 4.07Å; L232-I372 HydrophobicContact CD1-CG2 4.31Å; L232-P377 HydrophobicContact CD1-CB 4.17Å
233	L	50.8	Low	44.7	Very low	6 Å²	6	88.7 Å²	88.7	3%	0.031	48%	0.481	C	S	.	.	T	Hydrogen-bonded Turn	trans	-92.1	-15.9	179.7	-134.7	93.6	0	0	0	114.4	I139 L144 T231 V382 L386	I139-L233 HydrophobicContact CB-CD2 4.47Å; I139-L233 HydrophobicContact CG2-CD2 3.01Å; L144-L233 WeakPolarHBondContact CD2-O 3.37Å; T231-L233 PolarHBondContact O-N 3.45Å; L233-V382 HydrophobicContact CD1-CG1 4.15Å; L233-L386 HydrophobicContact CD1-CD2 4.23Å
234	C	48.9	Very low	44.6	Very low	8 Å²	8	87.9 Å²	87.9	5%	0.054	47%	0.465	C	S	.	.	T	Hydrogen-bonded Turn	trans	-112.5	-0.3	-172.5	-92.6	0	0	0	0	114.7	L144 C152 N229 T231 S236	L144-C234 HydrophobicContact CD2-CB 4.14Å; L144-C234 VanDerWaalsContact CD2-SG 3.6Å; C152-C234 HydrophobicContact CB-CB 3.76Å; C152-C234 WeakPolarHBondContact CB-SG 3.48Å; C152-C234 WeakPolarHBondContact SG-CB 3.29Å; C152-C234 CovalentContact SG-SG 2.03Å; C152-C234 PolarHBondContact SG-SG 2.89Å; N229-C234 HydrophobicContact CB-CB 4.44Å; N229-C234 VanDerWaalsContact CB-O 3.31Å; N229-C234 WeakPolarHBondContact CB-O 3.43Å; T231-C234 WeakPolarHBondContact O-CA 3.32Å; T231-C234 PolarHBondContact O-N 3.18Å; C234-S236 PolarHBondContact O-N 3.3Å
235	V	45	Very low	44.8	Very low	30 Å²	30	86.7 Å²	86.7	18%	0.182	45%	0.453	C	S	.	.			trans	-75.9	113.4	175	-178.2	0	0	0	0	108.9	N229 T231 E239 M246	N229-V235 WeakPolarHBondContact O-CG2 3.3Å; T231-V235 WeakPolarHBondContact O-CG2 3.14Å; T231-V235 PolarHBondContact O-N 3.38Å; V235-E239 WeakPolarHBondContact CG1-O 3.35Å; V235-M246 HydrophobicContact CG2-CE 4.14Å
236	S	41.1	Very low	45.1	Very low	91 Å²	91	80.3 Å²	80.3	64%	0.636	42%	0.418	S	S	*	.			trans	-56.9	138.9	174.6	-162.1	0	0	0	0	110.6	C234 S238	C234-S236 PolarHBondContact O-N 3.3Å; S236-S238 PolarHBondContact O-N 3.43Å
237	T	42.2	Very low	46	Very low	88 Å²	88	77 Å²	77	54%	0.54	39%	0.394	S	S	.	.	T	Hydrogen-bonded Turn	trans	-60.8	8.3	-170.1	29.9	0	0	0	0	116.9	L71	L71-T237 HydrophobicContact CD1-CG2 3.54Å
238	S	37.9	Very low	46.5	Very low	107 Å²	107	74 Å²	74	75%	0.748	38%	0.383	S	S	*	.	T	Hydrogen-bonded Turn	trans	-85.5	-34.7	179	-169	0	0	0	0	113.3	S236	S236-S238 PolarHBondContact O-N 3.43Å
239	E	38.7	Very low	47.3	Very low	104 Å²	104	68.9 Å²	68.9	49%	0.486	36%	0.359	S	S	.	.			trans	-152.2	107.7	-177.4	-69.3	-179.1	136.9	0	0	108.4	V235 Y241	V235-E239 WeakPolarHBondContact CG1-O 3.35Å; E239-Y241 HydrophobicContact CB-CD2 3.65Å; E239-Y241 HydrophobicContact CB-CE2 3.41Å; E239-Y241 VanDerWaalsContact CB-CE2 3.41Å; E239-Y241 HydrophobicContact CG-CE2 4.16Å; E239-Y241 WeakPolarHBondContact O-CD2 3.45Å; E239-Y241 PolarHBondContact O-N 3.35Å; E239-Y241 WeakPolarHBondContact OE2-CE2 3.44Å; E239-Y241 PolarHBondContact OE2-OH 3.4Å
240	Y	41.8	Very low	48.3	Very low	110 Å²	110	66.8 Å²	66.8	43%	0.431	35%	0.348	S	S	.	.			trans	-63.6	82.6	162.2	-74.6	-81.4	0	0	0	107.3	T242 P377	Y240-T242 PolarHBondContact O-N 3.33Å; Y240-P377 HydrophobicContact CD1-CB 4.34Å; Y240-P377 HydrophobicContact CD1-CG 3.54Å; Y240-P377 HydrophobicContact CE1-CB 3.88Å; Y240-P377 HydrophobicContact CE1-CG 3.58Å; Y240-P377 HydrophobicContact CG-CG 4.41Å
241	Y	38.8	Very low	49.2	Very low	147 Å²	147	65.8 Å²	65.8	58%	0.576	35%	0.347	S	S	*	.			trans	-62.2	97	168.3	-81.1	-82.9	0	0	0	106.8	E239 E243	E239-Y241 HydrophobicContact CB-CD2 3.65Å; E239-Y241 HydrophobicContact CB-CE2 3.41Å; E239-Y241 VanDerWaalsContact CB-CE2 3.41Å; E239-Y241 HydrophobicContact CG-CE2 4.16Å; E239-Y241 WeakPolarHBondContact O-CD2 3.45Å; E239-Y241 PolarHBondContact O-N 3.35Å; E239-Y241 WeakPolarHBondContact OE2-CE2 3.44Å; E239-Y241 PolarHBondContact OE2-OH 3.4Å; Y241-E243 PolarHBondContact O-N 2.92Å
242	T	40.8	Very low	50.2	Low	109 Å²	109	68.1 Å²	68.1	67%	0.669	36%	0.361	S	S	*	.			trans	-73.3	52.2	173.5	38.9	0	0	0	0	109.1	Y240	Y240-T242 PolarHBondContact O-N 3.33Å
243	E	45.3	Very low	51.4	Low	121 Å²	121	67.8 Å²	67.8	57%	0.565	36%	0.359	S	S	*	.			trans	-75.7	133.7	170.3	-80	-67.6	156.3	0	0	108.8	Y241 G245 M246	Y241-E243 PolarHBondContact O-N 2.92Å; E243-G245 PolarHBondContact O-N 3.15Å; E243-M246 PolarHBondContact O-N 3.24Å
244	L	43.8	Very low	52.8	Low	116 Å²	116	68.4 Å²	68.4	61%	0.607	36%	0.362	S	S	*	.	G	3₁₀ helix	trans	-52.9	-20.3	-170.5	-151.2	72.6	0	0	0	113.6	M246 Y248	L244-M246 VanDerWaalsContact C-N 3.32Å; L244-M246 PolarHBondContact O-N 3.32Å; L244-Y248 HydrophobicContact CB-CE2 4.46Å; L244-Y248 VanDerWaalsContact CD2-OH 3.26Å; L244-Y248 WeakPolarHBondContact CD2-OH 3.47Å; L244-Y248 HydrophobicContact CG-CE2 4.26Å; L244-Y248 VanDerWaalsContact O-CD2 3.22Å; L244-Y248 WeakPolarHBondContact O-CD2 3.34Å; L244-Y248 WeakPolarHBondContact O-CE2 3.34Å
245	G	46.4	Very low	54.4	Low	32 Å²	32	71.5 Å²	71.5	33%	0.33	38%	0.382	S	S	.	.	G	3₁₀ helix	trans	-62.3	-26.4	-179.3	0	0	0	0	0	115.7	E243 Y247	E243-G245 PolarHBondContact O-N 3.15Å; G245-Y247 VanDerWaalsContact C-N 3.28Å; G245-Y247 PolarHBondContact O-N 2.82Å
246	M	53.8	Low	56	Low	28 Å²	28	72.5 Å²	72.5	14%	0.138	39%	0.386	C	S	.	.	G	3₁₀ helix	trans	-74.9	-13.3	-173.1	-71.1	-80.8	-79.5	0	0	114.9	T231 L232 V235 E243 L244 H249	T231-M246 VanDerWaalsContact C-CE 3.49Å; L232-M246 HydrophobicContact CB-CE 3.88Å; L232-M246 HydrophobicContact CD1-CE 4.07Å; V235-M246 HydrophobicContact CG2-CE 4.14Å; E243-M246 PolarHBondContact O-N 3.24Å; L244-M246 VanDerWaalsContact C-N 3.32Å; L244-M246 PolarHBondContact O-N 3.32Å; M246-H249 PolarHBondContact O-CE1 3.35Å
247	Y	61.2	Low	58	Low	44 Å²	44	68.8 Å²	68.8	17%	0.173	36%	0.358	C	S	.	.	G	3₁₀ helix	trans	-105.5	-11.3	-171.4	-64.9	-71.5	0	0	0	113.8	G245 L250 L251 L373	G245-Y247 VanDerWaalsContact C-N 3.28Å; G245-Y247 PolarHBondContact O-N 2.82Å; Y247-L250 PolarHBondContact O-N 2.82Å; Y247-L251 VanDerWaalsContact O-CB 3.23Å; Y247-L251 WeakPolarHBondContact O-CB 3.39Å; Y247-L251 WeakPolarHBondContact O-CD1 3.33Å; Y247-L251 WeakPolarHBondContact O-CG 3.17Å; Y247-L251 PolarHBondContact O-N 2.9Å; Y247-L373 HydrophobicContact CD1-CD1 3.26Å; Y247-L373 HydrophobicContact CD1-CG 4.46Å; Y247-L373 HydrophobicContact CE1-CD1 4.05Å; Y247-L373 HydrophobicContact CG-CD1 3.72Å
248	Y	59.7	Low	59.9	Low	111 Å²	111	68.9 Å²	68.9	44%	0.435	35%	0.351	S	S	.	.	H	α-helix	trans	-69.8	-40.9	-171.1	-72.8	-74.4	0	0	0	113.1	E215 L244 L250 L251 V252	E215-Y248 WeakPolarHBondContact OE1-CB 3.39Å; L244-Y248 HydrophobicContact CB-CE2 4.46Å; L244-Y248 VanDerWaalsContact CD2-OH 3.26Å; L244-Y248 WeakPolarHBondContact CD2-OH 3.47Å; L244-Y248 HydrophobicContact CG-CE2 4.26Å; L244-Y248 VanDerWaalsContact O-CD2 3.22Å; L244-Y248 WeakPolarHBondContact O-CD2 3.34Å; L244-Y248 WeakPolarHBondContact O-CE2 3.34Å; Y248-L250 VanDerWaalsContact C-N 3.33Å; Y248-L250 PolarHBondContact O-N 3.34Å; Y248-L251 HydrophobicContact CD1-CD1 4.32Å; Y248-L251 CarbonylContact O-C 3.44Å; Y248-L251 WeakPolarHBondContact O-CB 3.48Å; Y248-L251 PolarHBondContact O-N 3.38Å; Y248-L251 VanDerWaalsContact O-N 3.15Å; Y248-V252 WeakPolarHBondContact O-CG2 3.47Å; Y248-V252 PolarHBondContact O-N 3.27Å
249	H	65.9	Low	62.1	Low	14 Å²	14	69.9 Å²	69.9	7%	0.065	34%	0.342	C	S	.	.	H	α-helix	trans	-69.5	-37.3	179.3	65	-82.2	0	0	0	110.5	E156 I211 P212 E215 M246 V252 Q253	E156-H249 IonicContact OE2-NE2 3.22Å; I211-H249 HydrophobicContact CG2-CB 3.85Å; P212-H249 HydrophobicContact CG-CB 4.41Å; E215-H249 VanDerWaalsContact OE1-CA 3.24Å; E215-H249 WeakPolarHBondContact OE1-CA 3.48Å; E215-H249 WeakPolarHBondContact OE1-CB 3.45Å; E215-H249 PolarHBondContact OE1-N 2.96Å; E215-H249 WeakPolarHBondContact OE2-CB 3.13Å; E215-H249 IonicContact OE2-CG 2.74Å; E215-H249 PolarHBondContact OE2-N 2.9Å; E215-H249 IonicContact OE2-ND1 3.57Å; E215-H249 PolarHBondContact OE2-ND1 3.45Å; M246-H249 PolarHBondContact O-CE1 3.35Å; H249-V252 PolarHBondContact O-N 2.84Å; H249-Q253 WeakPolarHBondContact O-CB 3.43Å; H249-Q253 PolarHBondContact O-N 3.28Å
250	L	69.6	Low	64.2	Low	2 Å²	2	65.2 Å²	65.2	1%	0.01	32%	0.321	C	S	.	.	H	α-helix	trans	-63	-42.5	171.5	-59.9	-178.4	0	0	0	111.1	Y247 Y248 V252 Q253 I254 N369	Y247-L250 PolarHBondContact O-N 2.82Å; Y248-L250 VanDerWaalsContact C-N 3.33Å; Y248-L250 PolarHBondContact O-N 3.34Å; L250-V252 PolarHBondContact O-N 3.19Å; L250-Q253 PolarHBondContact O-N 3.41Å; L250-I254 HydrophobicContact CB-CD1 4.48Å; L250-I254 VanDerWaalsContact O-CB 3.32Å; L250-I254 WeakPolarHBondContact O-CB 3.08Å; L250-I254 WeakPolarHBondContact O-CD1 3.34Å; L250-I254 WeakPolarHBondContact O-CG1 3.46Å; L250-I254 PolarHBondContact O-N 2.96Å; L250-N369 HydrophobicContact CD2-CB 4.06Å
251	L	67.2	Low	66.2	Low	79 Å²	79	61 Å²	61	41%	0.414	31%	0.307	S	S	.	.	H	α-helix	trans	-64.8	-23.4	176.1	-78.2	168.6	0	0	0	113.3	Y247 Y248 P255 L373	Y247-L251 VanDerWaalsContact O-CB 3.23Å; Y247-L251 WeakPolarHBondContact O-CB 3.39Å; Y247-L251 WeakPolarHBondContact O-CD1 3.33Å; Y247-L251 WeakPolarHBondContact O-CG 3.17Å; Y247-L251 PolarHBondContact O-N 2.9Å; Y248-L251 HydrophobicContact CD1-CD1 4.32Å; Y248-L251 CarbonylContact O-C 3.44Å; Y248-L251 WeakPolarHBondContact O-CB 3.48Å; Y248-L251 PolarHBondContact O-N 3.38Å; Y248-L251 VanDerWaalsContact O-N 3.15Å; L251-P255 WeakPolarHBondContact O-CD 3.48Å; L251-P255 WeakPolarHBondContact O-CG 3.37Å; L251-L373 HydrophobicContact CD2-CD1 4.27Å; L251-L373 HydrophobicContact CD2-CD2 3.58Å; L251-L373 HydrophobicContact CG-CD1 4.22Å; L251-L373 HydrophobicContact CG-CD2 4.2Å
252	V	67.3	Low	68.5	Low	61 Å²	61	58.6 Å²	58.6	37%	0.37	30%	0.303	S	S	.	.	H	α-helix	trans	-89.1	-40.3	173.4	174.9	0	0	0	0	111.3	I211 Y248 H249 L250 P255 I256	I211-V252 HydrophobicContact CD1-CB 4.45Å; I211-V252 HydrophobicContact CD1-CG1 3.84Å; Y248-V252 WeakPolarHBondContact O-CG2 3.47Å; Y248-V252 PolarHBondContact O-N 3.27Å; H249-V252 PolarHBondContact O-N 2.84Å; L250-V252 PolarHBondContact O-N 3.19Å; V252-P255 WeakPolarHBondContact O-CD 3.42Å; V252-I256 HydrophobicContact CG1-CD1 3.64Å; V252-I256 WeakPolarHBondContact O-CD1 3.48Å; V252-I256 VanDerWaalsContact O-CG1 3.22Å; V252-I256 WeakPolarHBondContact O-CG1 3.27Å; V252-I256 PolarHBondContact O-N 3.31Å
253	Q	72.9	Confident	70.5	Confident	15 Å²	15	54.9 Å²	54.9	7%	0.07	28%	0.28	C	S	.	.	H	α-helix	trans	-68.2	-39.7	-177.6	-167.8	-179	20.8	0	0	112.3	S163 H249 L250 I256 F257	S163-Q253 PolarHBondContact OG-NE2 3.45Å; H249-Q253 WeakPolarHBondContact O-CB 3.43Å; H249-Q253 PolarHBondContact O-N 3.28Å; L250-Q253 PolarHBondContact O-N 3.41Å; Q253-I256 PolarHBondContact O-N 3.39Å; Q253-F257 WeakPolarHBondContact O-CB 3.36Å; Q253-F257 PolarHBondContact O-N 3.05Å
254	I	80.3	Confident	72.3	Confident	20 Å²	20	49.2 Å²	49.2	10%	0.103	25%	0.253	C	S	.	.	H	α-helix	trans	-62	-54.2	-179	-71.5	165.2	0	0	0	111.6	L250 I256 F257 F258 N369 L373	L250-I254 HydrophobicContact CB-CD1 4.48Å; L250-I254 VanDerWaalsContact O-CB 3.32Å; L250-I254 WeakPolarHBondContact O-CB 3.08Å; L250-I254 WeakPolarHBondContact O-CD1 3.34Å; L250-I254 WeakPolarHBondContact O-CG1 3.46Å; L250-I254 PolarHBondContact O-N 2.96Å; I254-I256 VanDerWaalsContact C-N 3.34Å; I254-I256 PolarHBondContact O-N 2.96Å; I254-F257 PolarHBondContact O-N 3.49Å; I254-F258 HydrophobicContact CG2-CD2 3.62Å; I254-F258 HydrophobicContact CG2-CE2 3.55Å; I254-F258 WeakPolarHBondContact O-CD2 3.44Å; I254-F258 PolarHBondContact O-N 3.37Å; I254-N369 HydrophobicContact CD1-CB 4.45Å; I254-L373 HydrophobicContact CD1-CD2 4.09Å
255	P	82	Confident	74.3	Confident	73 Å²	73	48.3 Å²	48.3	47%	0.474	25%	0.248	S	C	.	.	H	α-helix	trans	-60.7	-39.4	176.4	-25.9	35.2	0	0	0	113.5	L251 V252 F257 F258 F259	L251-P255 WeakPolarHBondContact O-CD 3.48Å; L251-P255 WeakPolarHBondContact O-CG 3.37Å; V252-P255 WeakPolarHBondContact O-CD 3.42Å; P255-F257 VanDerWaalsContact C-N 3.34Å; P255-F257 PolarHBondContact O-N 3.04Å; P255-F258 PolarHBondContact O-N 2.95Å; P255-F259 WeakPolarHBondContact O-CB 3.17Å; P255-F259 PolarHBondContact O-N 2.89Å
256	I	78.7	Confident	76.1	Confident	51 Å²	51	51.3 Å²	51.3	26%	0.262	26%	0.256	S	S	.	.	H	α-helix	trans	-61.3	-46.5	177.5	-69.1	169.7	0	0	0	109.9	V164 V252 Q253 I254 F259 T260	V164-I256 HydrophobicContact CG2-CD1 4.28Å; V164-I256 HydrophobicContact CG2-CG2 4.25Å; V252-I256 HydrophobicContact CG1-CD1 3.64Å; V252-I256 WeakPolarHBondContact O-CD1 3.48Å; V252-I256 VanDerWaalsContact O-CG1 3.22Å; V252-I256 WeakPolarHBondContact O-CG1 3.27Å; V252-I256 PolarHBondContact O-N 3.31Å; Q253-I256 PolarHBondContact O-N 3.39Å; I254-I256 VanDerWaalsContact C-N 3.34Å; I254-I256 PolarHBondContact O-N 2.96Å; I256-F259 PolarHBondContact O-N 2.93Å; I256-T260 HydrophobicContact CG2-CG2 4.34Å; I256-T260 WeakPolarHBondContact O-CG2 3.47Å; I256-T260 PolarHBondContact O-N 3.02Å; I256-T260 PolarHBondContact O-OG1 3.05Å
257	F	82.8	Confident	77.5	Confident	12 Å²	12	50.8 Å²	50.8	5%	0.053	25%	0.254	C	S	.	.	H	α-helix	trans	-58.6	-55.2	176.3	178.7	-100.9	0	0	0	111.1	Q253 I254 P255 F259 T260 V261 F358 W362 S366	Q253-F257 WeakPolarHBondContact O-CB 3.36Å; Q253-F257 PolarHBondContact O-N 3.05Å; I254-F257 PolarHBondContact O-N 3.49Å; P255-F257 VanDerWaalsContact C-N 3.34Å; P255-F257 PolarHBondContact O-N 3.04Å; F257-F259 VanDerWaalsContact C-N 3.32Å; F257-F259 PolarHBondContact O-N 3.42Å; F257-T260 PolarHBondContact O-N 2.65Å; F257-T260 VanDerWaalsContact O-N 3.12Å; F257-T260 PolarHBondContact O-OG1 2.79Å; F257-V261 HydrophobicContact CD1-CG2 4.25Å; F257-V261 HydrophobicContact CD2-CG2 4.46Å; F257-V261 HydrophobicContact CE1-CG2 3.86Å; F257-V261 HydrophobicContact CE2-CG2 4.07Å; F257-V261 HydrophobicContact CZ-CG2 3.75Å; F257-V261 WeakPolarHBondContact O-CG2 3.47Å; F257-V261 PolarHBondContact O-N 2.79Å; F257-F358 HydrophobicContact CD2-CE1 4.42Å; F257-F358 HydrophobicContact CD2-CZ 4.1Å; F257-F358 AromaticContact CE2-CE1 3.93Å; F257-F358 HydrophobicContact CE2-CE1 3.93Å; F257-F358 AromaticContact CE2-CZ 3.89Å; F257-F358 HydrophobicContact CE2-CZ 3.89Å; F257-W362 HydrophobicContact CD2-CB 4.46Å; F257-W362 HydrophobicContact CE2-CB 3.69Å; F257-W362 HydrophobicContact CZ-CB 4.41Å; F257-S366 WeakPolarHBondContact CD1-OG 3.2Å; F257-S366 WeakPolarHBondContact CD2-OG 3.33Å; F257-S366 VanDerWaalsContact CG-OG 3.29Å; F257-S366 WeakPolarHBondContact CG-OG 3.33Å
258	F	84.1	Confident	78.5	Confident	91 Å²	91	49.2 Å²	49.2	40%	0.399	25%	0.248	S	C	.	.	H	α-helix	trans	-61.8	-38.8	-179.1	-75.9	-65.4	0	0	0	113	I254 P255 V261 I262	I254-F258 HydrophobicContact CG2-CD2 3.62Å; I254-F258 HydrophobicContact CG2-CE2 3.55Å; I254-F258 WeakPolarHBondContact O-CD2 3.44Å; I254-F258 PolarHBondContact O-N 3.37Å; P255-F258 PolarHBondContact O-N 2.95Å; F258-V261 PolarHBondContact O-N 2.99Å; F258-I262 WeakPolarHBondContact O-CB 3.42Å; F258-I262 VanDerWaalsContact O-CG1 3.23Å; F258-I262 WeakPolarHBondContact O-CG1 3.36Å; F258-I262 PolarHBondContact O-N 3.45Å
259	F	83.7	Confident	79.6	Confident	128 Å²	128	47.3 Å²	47.3	56%	0.561	25%	0.248	S	C	*	.	H	α-helix	trans	-59.1	-49	173.2	174.1	-100.8	0	0	0	111.2	P255 I256 F257 V261 I262 V263	P255-F259 WeakPolarHBondContact O-CB 3.17Å; P255-F259 PolarHBondContact O-N 2.89Å; I256-F259 PolarHBondContact O-N 2.93Å; F257-F259 VanDerWaalsContact C-N 3.32Å; F257-F259 PolarHBondContact O-N 3.42Å; F259-V261 VanDerWaalsContact C-N 3.32Å; F259-V261 PolarHBondContact O-N 2.79Å; F259-I262 PolarHBondContact O-N 3.43Å; F259-V263 HydrophobicContact CD2-CG2 4.17Å; F259-V263 HydrophobicContact CE1-CG2 4.15Å; F259-V263 HydrophobicContact CE2-CG2 3.78Å; F259-V263 HydrophobicContact CZ-CG2 3.77Å; F259-V263 VanDerWaalsContact O-CG2 3.32Å; F259-V263 WeakPolarHBondContact O-CG2 3.04Å; F259-V263 PolarHBondContact O-N 3.06Å
260	T	81.3	Confident	80.4	Confident	5 Å²	5	51.7 Å²	51.7	3%	0.031	27%	0.267	C	S	.	.	H	α-helix	trans	-59.7	-42.9	177.6	64.8	0	0	0	0	111.5	A167 I256 F257 V263 M264	A167-T260 HydrophobicContact CB-CG2 3.77Å; I256-T260 HydrophobicContact CG2-CG2 4.34Å; I256-T260 WeakPolarHBondContact O-CG2 3.47Å; I256-T260 PolarHBondContact O-N 3.02Å; I256-T260 PolarHBondContact O-OG1 3.05Å; F257-T260 PolarHBondContact O-N 2.65Å; F257-T260 VanDerWaalsContact O-N 3.12Å; F257-T260 PolarHBondContact O-OG1 2.79Å; T260-V263 PolarHBondContact O-N 2.9Å; T260-M264 VanDerWaalsContact O-CB 3.26Å; T260-M264 WeakPolarHBondContact O-CB 3.18Å; T260-M264 WeakPolarHBondContact O-CG 3.46Å; T260-M264 PolarHBondContact O-N 3.47Å
261	V	85.5	Confident	81	Confident	22 Å²	22	51.6 Å²	51.6	13%	0.133	27%	0.266	C	S	.	.	H	α-helix	trans	-62.8	-47.5	177.3	174.7	0	0	0	0	111.7	F257 F258 F259 V263 M264 L265 L359	F257-V261 HydrophobicContact CD1-CG2 4.25Å; F257-V261 HydrophobicContact CD2-CG2 4.46Å; F257-V261 HydrophobicContact CE1-CG2 3.86Å; F257-V261 HydrophobicContact CE2-CG2 4.07Å; F257-V261 HydrophobicContact CZ-CG2 3.75Å; F257-V261 WeakPolarHBondContact O-CG2 3.47Å; F257-V261 PolarHBondContact O-N 2.79Å; F258-V261 PolarHBondContact O-N 2.99Å; F259-V261 VanDerWaalsContact C-N 3.32Å; F259-V261 PolarHBondContact O-N 2.79Å; V261-V263 PolarHBondContact O-N 3.14Å; V261-M264 PolarHBondContact O-N 3.37Å; V261-L265 HydrophobicContact CG1-CD1 3.86Å; V261-L265 HydrophobicContact CG1-CG 4.28Å; V261-L265 WeakPolarHBondContact O-CB 3.42Å; V261-L265 VanDerWaalsContact O-CG 3.28Å; V261-L265 WeakPolarHBondContact O-CG 3.23Å; V261-L265 PolarHBondContact O-N 3.38Å; V261-L359 HydrophobicContact CB-CD2 4.27Å; V261-L359 HydrophobicContact CG1-CD2 3.89Å; V261-L359 HydrophobicContact CG2-CD2 3.51Å
262	I	87.1	Confident	81.7	Confident	96 Å²	96	51.6 Å²	51.6	49%	0.492	27%	0.267	S	S	.	.	H	α-helix	trans	-59.7	-48.9	179.5	-71.5	165.3	0	0	0	110.5	F258 F259 M264 L265 I266	F258-I262 WeakPolarHBondContact O-CB 3.42Å; F258-I262 VanDerWaalsContact O-CG1 3.23Å; F258-I262 WeakPolarHBondContact O-CG1 3.36Å; F258-I262 PolarHBondContact O-N 3.45Å; F259-I262 PolarHBondContact O-N 3.43Å; I262-M264 VanDerWaalsContact C-N 3.33Å; I262-M264 PolarHBondContact O-N 3.42Å; I262-L265 PolarHBondContact O-N 3.48Å; I262-I266 HydrophobicContact CG2-CD1 3.79Å; I262-I266 WeakPolarHBondContact O-CG1 3.5Å; I262-I266 PolarHBondContact O-N 3.34Å
263	V	82.1	Confident	82.4	Confident	31 Å²	31	53 Å²	53	19%	0.188	27%	0.269	C	S	.	.	H	α-helix	trans	-64.2	-41.1	-179.8	178.6	0	0	0	0	110.8	F171 F259 T260 V261 I266 T267	F171-V263 HydrophobicContact CD2-CG1 3.89Å; F171-V263 HydrophobicContact CE2-CB 4.28Å; F171-V263 HydrophobicContact CE2-CG1 3.2Å; F171-V263 HydrophobicContact CZ-CG1 3.8Å; F259-V263 HydrophobicContact CD2-CG2 4.17Å; F259-V263 HydrophobicContact CE1-CG2 4.15Å; F259-V263 HydrophobicContact CE2-CG2 3.78Å; F259-V263 HydrophobicContact CZ-CG2 3.77Å; F259-V263 VanDerWaalsContact O-CG2 3.32Å; F259-V263 WeakPolarHBondContact O-CG2 3.04Å; F259-V263 PolarHBondContact O-N 3.06Å; T260-V263 PolarHBondContact O-N 2.9Å; V261-V263 PolarHBondContact O-N 3.14Å; V263-I266 PolarHBondContact O-N 3.2Å; V263-T267 HydrophobicContact CG1-CG2 4.34Å; V263-T267 WeakPolarHBondContact O-CB 3.46Å; V263-T267 VanDerWaalsContact O-CG2 3.31Å; V263-T267 WeakPolarHBondContact O-CG2 3.37Å; V263-T267 PolarHBondContact O-N 3.16Å; V263-T267 PolarHBondContact O-OG1 3.02Å
264	M	83.3	Confident	82.6	Confident	3 Å²	3	53.2 Å²	53.2	2%	0.015	27%	0.273	C	S	.	.	H	α-helix	trans	-62.2	-43.1	175.2	-75.1	170.5	50.8	0	0	112.1	V170 T260 V261 I262 T267 Y268 I355 F358	V170-M264 HydrophobicContact CG1-CE 3.47Å; V170-M264 VanDerWaalsContact CG1-CE 3.47Å; V170-M264 HydrophobicContact CG1-SD 3.87Å; T260-M264 VanDerWaalsContact O-CB 3.26Å; T260-M264 WeakPolarHBondContact O-CB 3.18Å; T260-M264 WeakPolarHBondContact O-CG 3.46Å; T260-M264 PolarHBondContact O-N 3.47Å; V261-M264 PolarHBondContact O-N 3.37Å; I262-M264 VanDerWaalsContact C-N 3.33Å; I262-M264 PolarHBondContact O-N 3.42Å; M264-T267 WeakPolarHBondContact CA-OG1 3.49Å; M264-T267 PolarHBondContact O-OG1 3.48Å; M264-Y268 WeakPolarHBondContact O-CB 3.46Å; M264-Y268 VanDerWaalsContact O-CD2 3.31Å; M264-Y268 WeakPolarHBondContact O-CD2 3.11Å; M264-Y268 PolarHBondContact O-N 3.18Å; M264-I355 HydrophobicContact CE-CB 3.87Å; M264-I355 HydrophobicContact CE-CD1 3.89Å; M264-I355 HydrophobicContact CE-CG1 3.55Å; M264-I355 HydrophobicContact CE-CG2 3.3Å; M264-F358 HydrophobicContact CE-CD1 4.01Å; M264-F358 HydrophobicContact SD-CD1 4.42Å; M264-F358 HydrophobicContact SD-CE1 4.41Å
265	L	85.4	Confident	82.2	Confident	96 Å²	96	53.6 Å²	53.6	50%	0.503	28%	0.276	S	S	.	.	H	α-helix	trans	-62	-49.5	176.7	-72.5	171.1	0	0	0	111.3	V261 I262 T267 Y268 T269	V261-L265 HydrophobicContact CG1-CD1 3.86Å; V261-L265 HydrophobicContact CG1-CG 4.28Å; V261-L265 WeakPolarHBondContact O-CB 3.42Å; V261-L265 VanDerWaalsContact O-CG 3.28Å; V261-L265 WeakPolarHBondContact O-CG 3.23Å; V261-L265 PolarHBondContact O-N 3.38Å; I262-L265 PolarHBondContact O-N 3.48Å; L265-T267 PolarHBondContact O-N 2.89Å; L265-Y268 PolarHBondContact O-N 3.47Å; L265-T269 PolarHBondContact O-N 3.3Å; L265-T269 PolarHBondContact O-OG1 3.17Å
266	I	85.3	Confident	81.7	Confident	96 Å²	96	55.4 Å²	55.4	49%	0.492	28%	0.281	S	S	.	.	H	α-helix	trans	-58.5	-50.9	-180	-68.5	168	0	0	0	110.8	I262 V263 Y268 T269 K270	I262-I266 HydrophobicContact CG2-CD1 3.79Å; I262-I266 WeakPolarHBondContact O-CG1 3.5Å; I262-I266 PolarHBondContact O-N 3.34Å; V263-I266 PolarHBondContact O-N 3.2Å; I266-Y268 VanDerWaalsContact C-N 3.29Å; I266-Y268 PolarHBondContact O-N 2.9Å; I266-T269 PolarHBondContact O-N 2.97Å; I266-K270 VanDerWaalsContact O-CG 3.27Å; I266-K270 WeakPolarHBondContact O-CG 3.19Å; I266-K270 PolarHBondContact O-N 3.39Å
267	T	82.6	Confident	80.9	Confident	16 Å²	16	58 Å²	58	10%	0.098	29%	0.294	C	S	.	.	H	α-helix	trans	-60.7	-39.3	-179.4	48.8	0	0	0	0	111.5	T174 V263 M264 L265 K270 I271	T174-T267 HydrophobicContact CG2-CG2 4.32Å; T174-T267 WeakPolarHBondContact CG2-OG1 3.22Å; V263-T267 HydrophobicContact CG1-CG2 4.34Å; V263-T267 WeakPolarHBondContact O-CB 3.46Å; V263-T267 VanDerWaalsContact O-CG2 3.31Å; V263-T267 WeakPolarHBondContact O-CG2 3.37Å; V263-T267 PolarHBondContact O-N 3.16Å; V263-T267 PolarHBondContact O-OG1 3.02Å; M264-T267 WeakPolarHBondContact CA-OG1 3.49Å; M264-T267 PolarHBondContact O-OG1 3.48Å; L265-T267 PolarHBondContact O-N 2.89Å; T267-K270 PolarHBondContact O-N 2.93Å; T267-I271 WeakPolarHBondContact O-CG1 3.22Å; T267-I271 PolarHBondContact O-N 3.27Å
268	Y	81.1	Confident	80	Confident	12 Å²	12	59.9 Å²	59.9	5%	0.047	30%	0.301	C	S	.	.	H	α-helix	trans	-71.1	-39.7	177	-92.6	-98.4	0	0	0	114.1	T174 M264 L265 I266 K270 I271 L272 F348 S351 L352 I355	T174-Y268 HydrophobicContact CG2-CD2 3.77Å; T174-Y268 HydrophobicContact CG2-CE2 3.46Å; T174-Y268 VanDerWaalsContact CG2-CE2 3.46Å; M264-Y268 WeakPolarHBondContact O-CB 3.46Å; M264-Y268 VanDerWaalsContact O-CD2 3.31Å; M264-Y268 WeakPolarHBondContact O-CD2 3.11Å; M264-Y268 PolarHBondContact O-N 3.18Å; L265-Y268 PolarHBondContact O-N 3.47Å; I266-Y268 VanDerWaalsContact C-N 3.29Å; I266-Y268 PolarHBondContact O-N 2.9Å; Y268-K270 PolarHBondContact O-N 3.38Å; Y268-I271 HydrophobicContact CD2-CD1 4.32Å; Y268-I271 HydrophobicContact CE2-CD1 4.26Å; Y268-I271 PolarHBondContact O-N 2.91Å; Y268-I271 VanDerWaalsContact O-N 3.15Å; Y268-L272 WeakPolarHBondContact O-CB 3.14Å; Y268-L272 WeakPolarHBondContact O-CG 3.32Å; Y268-L272 PolarHBondContact O-N 3.48Å; Y268-F348 AromaticContact CD1-CE2 3.73Å; Y268-F348 HydrophobicContact CD1-CE2 3.73Å; Y268-F348 HydrophobicContact CD1-CZ 4.06Å; Y268-F348 HydrophobicContact CE1-CD2 4.27Å; Y268-F348 AromaticContact CE1-CE2 3.55Å; Y268-F348 HydrophobicContact CE1-CE2 3.55Å; Y268-F348 HydrophobicContact CE1-CZ 4.14Å; Y268-S351 VanDerWaalsContact OH-C 3.23Å; Y268-S351 WeakPolarHBondContact OH-CB 3.43Å; Y268-S351 PolarHBondContact OH-O 3.23Å; Y268-L352 HydrophobicContact CD1-CD1 4.08Å; Y268-L352 HydrophobicContact CE1-CB 4.22Å; Y268-L352 HydrophobicContact CE1-CD1 4.23Å; Y268-I355 HydrophobicContact CD2-CD1 3.62Å; Y268-I355 HydrophobicContact CE1-CD1 4.05Å; Y268-I355 HydrophobicContact CE2-CD1 2.86Å; Y268-I355 HydrophobicContact CE2-CG1 4.34Å; Y268-I355 HydrophobicContact CG-CD1 4.45Å; Y268-I355 WeakPolarHBondContact OH-CD1 3.44Å
269	T	83.9	Confident	78.8	Confident	71 Å²	71	59 Å²	59	44%	0.436	30%	0.3	S	S	.	.	H	α-helix	trans	-56.7	-43.1	171.7	-55.5	0	0	0	0	110	L265 I266 L272 Q273	L265-T269 PolarHBondContact O-N 3.3Å; L265-T269 PolarHBondContact O-OG1 3.17Å; I266-T269 PolarHBondContact O-N 2.97Å; T269-L272 PolarHBondContact O-N 2.86Å; T269-Q273 WeakPolarHBondContact O-CB 3Å; T269-Q273 VanDerWaalsContact O-CG 3.25Å; T269-Q273 WeakPolarHBondContact O-CG 3.27Å; T269-Q273 PolarHBondContact O-N 2.92Å
270	K	83.4	Confident	77.5	Confident	105 Å²	105	54.8 Å²	54.8	46%	0.457	29%	0.293	S	S	.	.	H	α-helix	trans	-67	-38.4	176.6	-63.5	-69.8	175	-178.8	0	112.7	Y178 I266 T267 Y268 Q273 A274	Y178-K270 HydrophobicContact CD2-CB 4.46Å; Y178-K270 HydrophobicContact CE2-CB 3.84Å; I266-K270 VanDerWaalsContact O-CG 3.27Å; I266-K270 WeakPolarHBondContact O-CG 3.19Å; I266-K270 PolarHBondContact O-N 3.39Å; T267-K270 PolarHBondContact O-N 2.93Å; Y268-K270 PolarHBondContact O-N 3.38Å; K270-Q273 PolarHBondContact O-N 3.41Å; K270-A274 WeakPolarHBondContact O-CB 3.36Å; K270-A274 PolarHBondContact O-N 3.37Å
271	I	82.4	Confident	76.4	Confident	0 Å²	0	57.8 Å²	57.8	0%	0	31%	0.311	C	S	.	.	H	α-helix	trans	-64.8	-46.1	175.1	-65.1	160.3	0	0	0	110.7	R177 Y178 V182 T267 Y268 Q273 A274 L275 F348	R177-I271 HydrophobicContact CB-CD1 4.25Å; Y178-I271 HydrophobicContact CD2-CG1 4.02Å; V182-I271 HydrophobicContact CG2-CG1 4.14Å; T267-I271 WeakPolarHBondContact O-CG1 3.22Å; T267-I271 PolarHBondContact O-N 3.27Å; Y268-I271 HydrophobicContact CD2-CD1 4.32Å; Y268-I271 HydrophobicContact CE2-CD1 4.26Å; Y268-I271 PolarHBondContact O-N 2.91Å; Y268-I271 VanDerWaalsContact O-N 3.15Å; I271-Q273 VanDerWaalsContact C-N 3.33Å; I271-Q273 PolarHBondContact O-N 3.44Å; I271-A274 PolarHBondContact O-N 3.22Å; I271-L275 HydrophobicContact CG2-CD1 3.91Å; I271-L275 HydrophobicContact CG2-CG 4.26Å; I271-L275 WeakPolarHBondContact O-CB 3.43Å; I271-L275 VanDerWaalsContact O-CG 3.3Å; I271-L275 WeakPolarHBondContact O-CG 3.2Å; I271-L275 PolarHBondContact O-N 2.85Å; I271-F348 HydrophobicContact CB-CD2 4.5Å; I271-F348 HydrophobicContact CB-CE2 3.94Å; I271-F348 HydrophobicContact CG2-CD2 3.38Å; I271-F348 HydrophobicContact CG2-CE2 3.21Å; I271-F348 HydrophobicContact CG2-CG 4.43Å; I271-F348 HydrophobicContact CG2-CZ 4.15Å
272	L	81.1	Confident	74.9	Confident	80 Å²	80	60.6 Å²	60.6	42%	0.419	32%	0.32	S	S	.	.	H	α-helix	trans	-60	-43.9	177.3	-73.9	171.8	0	0	0	111.4	Y268 T269 L275 N276 F348	Y268-L272 WeakPolarHBondContact O-CB 3.14Å; Y268-L272 WeakPolarHBondContact O-CG 3.32Å; Y268-L272 PolarHBondContact O-N 3.48Å; T269-L272 PolarHBondContact O-N 2.86Å; L272-L275 PolarHBondContact O-N 3.48Å; L272-N276 WeakPolarHBondContact O-CB 3.29Å; L272-N276 PolarHBondContact O-N 3.24Å; L272-F348 HydrophobicContact CD2-CE1 3.68Å; L272-F348 HydrophobicContact CD2-CZ 3.44Å; L272-F348 VanDerWaalsContact CD2-CZ 3.44Å; L272-F348 HydrophobicContact CG-CZ 3.92Å
273	Q	81.3	Confident	73.1	Confident	90 Å²	90	63.6 Å²	63.6	42%	0.421	33%	0.329	S	S	.	.	H	α-helix	trans	-60	-48.7	173.5	-75.1	174.5	-10.2	0	0	111.5	T269 K270 I271 L275 N276 I277	T269-Q273 WeakPolarHBondContact O-CB 3Å; T269-Q273 VanDerWaalsContact O-CG 3.25Å; T269-Q273 WeakPolarHBondContact O-CG 3.27Å; T269-Q273 PolarHBondContact O-N 2.92Å; K270-Q273 PolarHBondContact O-N 3.41Å; I271-Q273 VanDerWaalsContact C-N 3.33Å; I271-Q273 PolarHBondContact O-N 3.44Å; Q273-L275 VanDerWaalsContact C-N 3.3Å; Q273-L275 PolarHBondContact O-N 2.72Å; Q273-N276 PolarHBondContact O-N 3.21Å; Q273-I277 HydrophobicContact CB-CD1 4.5Å; Q273-I277 WeakPolarHBondContact O-CB 3.21Å; Q273-I277 WeakPolarHBondContact O-CG1 3.32Å; Q273-I277 PolarHBondContact O-N 3.43Å
274	A	76.8	Confident	71.5	Confident	19 Å²	19	64.9 Å²	64.9	16%	0.157	34%	0.339	C	S	.	.	H	α-helix	trans	-62	-37	178.6	0	0	0	0	0	112.5	V182 K270 I271 R278	V182-A274 HydrophobicContact CB-CB 4.38Å; V182-A274 HydrophobicContact CG1-CB 4.4Å; V182-A274 HydrophobicContact CG2-CB 3.8Å; K270-A274 WeakPolarHBondContact O-CB 3.36Å; K270-A274 PolarHBondContact O-N 3.37Å; I271-A274 PolarHBondContact O-N 3.22Å; A274-R278 WeakPolarHBondContact O-CB 3.49Å; A274-R278 PolarHBondContact O-N 3.33Å
275	L	73.6	Confident	70.1	Confident	29 Å²	29	68.5 Å²	68.5	15%	0.152	36%	0.362	C	S	.	.	H	α-helix	trans	-67.2	-43.8	175.2	-71.6	173.2	0	0	0	111.7	I271 L272 Q273 R278 I279 F348	I271-L275 HydrophobicContact CG2-CD1 3.91Å; I271-L275 HydrophobicContact CG2-CG 4.26Å; I271-L275 WeakPolarHBondContact O-CB 3.43Å; I271-L275 VanDerWaalsContact O-CG 3.3Å; I271-L275 WeakPolarHBondContact O-CG 3.2Å; I271-L275 PolarHBondContact O-N 2.85Å; L272-L275 PolarHBondContact O-N 3.48Å; Q273-L275 VanDerWaalsContact C-N 3.3Å; Q273-L275 PolarHBondContact O-N 2.72Å; L275-R278 PolarHBondContact O-N 3.23Å; L275-I279 WeakPolarHBondContact O-CD1 3.49Å; L275-I279 VanDerWaalsContact O-CG1 3.25Å; L275-I279 WeakPolarHBondContact O-CG1 3.44Å; L275-I279 PolarHBondContact O-N 3.1Å; L275-F348 HydrophobicContact CD1-CB 4.33Å; L275-F348 HydrophobicContact CD1-CD1 3.55Å; L275-F348 HydrophobicContact CD1-CD2 3.91Å; L275-F348 HydrophobicContact CD1-CE1 3.77Å; L275-F348 HydrophobicContact CD1-CE2 4.11Å; L275-F348 HydrophobicContact CD1-CG 3.62Å; L275-F348 HydrophobicContact CD1-CZ 4.04Å
276	N	71.6	Confident	68.4	Low	110 Å²	110	65.8 Å²	65.8	59%	0.588	36%	0.358	S	S	*	.	H	α-helix	trans	-69.3	-43.1	177.3	-80.7	-7.5	0	0	0	112.7	L272 Q273 R278 I279 G280	L272-N276 WeakPolarHBondContact O-CB 3.29Å; L272-N276 PolarHBondContact O-N 3.24Å; Q273-N276 PolarHBondContact O-N 3.21Å; N276-R278 VanDerWaalsContact C-N 3.28Å; N276-R278 PolarHBondContact O-N 2.8Å; N276-I279 CarbonylContact O-C 3.58Å; N276-I279 WeakPolarHBondContact O-CA 3.42Å; N276-I279 WeakPolarHBondContact O-CB 3.45Å; N276-I279 PolarHBondContact O-N 3.37Å; N276-G280 PolarHBondContact O-N 3.22Å
277	I	61.2	Low	66.8	Low	105 Å²	105	68.3 Å²	68.3	54%	0.538	37%	0.367	S	S	.	.	H	α-helix	trans	-60.7	-40.6	173.5	-67.8	165.8	0	0	0	109.9	Q273 I279 G280 T281	Q273-I277 HydrophobicContact CB-CD1 4.5Å; Q273-I277 WeakPolarHBondContact O-CB 3.21Å; Q273-I277 WeakPolarHBondContact O-CG1 3.32Å; Q273-I277 PolarHBondContact O-N 3.43Å; I277-I279 PolarHBondContact O-N 2.89Å; I277-G280 PolarHBondContact O-N 3.36Å; I277-T281 HydrophobicContact CG2-CG2 3.71Å; I277-T281 VanDerWaalsContact O-CB 3.31Å; I277-T281 WeakPolarHBondContact O-CB 3.4Å; I277-T281 VanDerWaalsContact O-CG2 3.29Å; I277-T281 WeakPolarHBondContact O-CG2 3.39Å; I277-T281 PolarHBondContact O-N 3.02Å; I277-T281 PolarHBondContact O-OG1 3.07Å
278	R	62.8	Low	65.1	Low	52 Å²	52	74.7 Å²	74.7	20%	0.196	39%	0.393	C	S	.	.	H	α-helix	trans	-68.6	-19.9	175.4	-176.3	177.5	-78.6	-173.5	15.4	112.9	S181 A274 L275 N276 R282	S181-R278 PolarHBondContact O-NH2 3.21Å; A274-R278 WeakPolarHBondContact O-CB 3.49Å; A274-R278 PolarHBondContact O-N 3.33Å; L275-R278 PolarHBondContact O-N 3.23Å; N276-R278 VanDerWaalsContact C-N 3.28Å; N276-R278 PolarHBondContact O-N 2.8Å; R278-R282 VanDerWaalsContact CD-NH2 3.33Å; R278-R282 VanDerWaalsContact CG-NH2 3.33Å; R278-R282 WeakPolarHBondContact O-CD 3.44Å; R278-R282 WeakPolarHBondContact O-CG 3.47Å; R278-R282 PolarHBondContact O-NE 3.46Å; R278-R282 VanDerWaalsContact O-NE 3.08Å
279	I	58.8	Low	63.6	Low	72 Å²	72	81.9 Å²	81.9	37%	0.369	43%	0.425	S	S	.	.	H	α-helix	trans	-79.8	-51.2	169.6	-67.9	158.4	0	0	0	109.2	L275 N276 I277 F283	L275-I279 WeakPolarHBondContact O-CD1 3.49Å; L275-I279 VanDerWaalsContact O-CG1 3.25Å; L275-I279 WeakPolarHBondContact O-CG1 3.44Å; L275-I279 PolarHBondContact O-N 3.1Å; N276-I279 CarbonylContact O-C 3.58Å; N276-I279 WeakPolarHBondContact O-CA 3.42Å; N276-I279 WeakPolarHBondContact O-CB 3.45Å; N276-I279 PolarHBondContact O-N 3.37Å; I277-I279 PolarHBondContact O-N 2.89Å; I279-F283 HydrophobicContact CG2-CE2 4.07Å; I279-F283 WeakPolarHBondContact O-CD2 3.46Å
280	G	56.8	Low	61.9	Low	41 Å²	41	86.4 Å²	86.4	42%	0.423	44%	0.439	S	S	.	.	H	α-helix	trans	-67.2	-44.5	-177.4	0	0	0	0	0	115.2	N276 I277 R282 F283 S284	N276-G280 PolarHBondContact O-N 3.22Å; I277-G280 PolarHBondContact O-N 3.36Å; G280-R282 VanDerWaalsContact C-N 3.26Å; G280-R282 PolarHBondContact O-N 3.09Å; G280-F283 PolarHBondContact O-N 3.06Å; G280-S284 PolarHBondContact O-N 2.86Å
281	T	58	Low	60.2	Low	68 Å²	68	84.3 Å²	84.3	42%	0.417	44%	0.441	S	S	.	.	H	α-helix	trans	-63.8	-29.3	179.9	52.1	0	0	0	0	113	I277 S284 T285	I277-T281 HydrophobicContact CG2-CG2 3.71Å; I277-T281 VanDerWaalsContact O-CB 3.31Å; I277-T281 WeakPolarHBondContact O-CB 3.4Å; I277-T281 VanDerWaalsContact O-CG2 3.29Å; I277-T281 WeakPolarHBondContact O-CG2 3.39Å; I277-T281 PolarHBondContact O-N 3.02Å; I277-T281 PolarHBondContact O-OG1 3.07Å; T281-S284 PolarHBondContact O-N 3.43Å; T281-T285 PolarHBondContact O-N 3.03Å; T281-T285 PolarHBondContact O-OG1 3.46Å
282	R	54	Low	58.4	Low	81 Å²	81	93.8 Å²	93.8	31%	0.306	48%	0.477	S	S	.	.	H	α-helix	trans	-74.3	-27.2	179.8	-68.7	-176.4	-161.2	-134.1	9.8	113.6	R278 G280 G286 H337 R341	R278-R282 VanDerWaalsContact CD-NH2 3.33Å; R278-R282 VanDerWaalsContact CG-NH2 3.33Å; R278-R282 WeakPolarHBondContact O-CD 3.44Å; R278-R282 WeakPolarHBondContact O-CG 3.47Å; R278-R282 PolarHBondContact O-NE 3.46Å; R278-R282 VanDerWaalsContact O-NE 3.08Å; G280-R282 VanDerWaalsContact C-N 3.26Å; G280-R282 PolarHBondContact O-N 3.09Å; R282-G286 PolarHBondContact O-N 3.09Å; R282-H337 PolarHBondContact NH1-CE1 3.4Å; R282-H337 PolarHBondContact NH1-NE2 3.16Å; R282-R341 VanDerWaalsContact CD-CZ 3.48Å; R282-R341 VanDerWaalsContact CZ-CZ 3.47Å; R282-R341 VanDerWaalsContact NH1-NE 3.19Å
283	F	49.2	Very low	56.7	Low	159 Å²	159	97.8 Å²	97.8	70%	0.697	49%	0.491	S	S	*	.	H	α-helix	trans	-72.5	-39.7	170.9	-72.8	-75.5	0	0	0	110.8	I279 G280 Q287	I279-F283 HydrophobicContact CG2-CE2 4.07Å; I279-F283 WeakPolarHBondContact O-CD2 3.46Å; G280-F283 PolarHBondContact O-N 3.06Å; F283-Q287 PolarHBondContact O-N 3.01Å
284	S	50	Low	54.9	Low	57 Å²	57	101.7 Å²	101.7	40%	0.399	51%	0.506	S	S	.	.	H	α-helix	trans	-69.4	-44.4	179.2	-167.2	0	0	0	0	113.4	G280 T281 G286 Q287 K288	G280-S284 PolarHBondContact O-N 2.86Å; T281-S284 PolarHBondContact O-N 3.43Å; S284-G286 VanDerWaalsContact C-N 3.34Å; S284-G286 PolarHBondContact O-N 3.1Å; S284-Q287 PolarHBondContact O-N 3.21Å; S284-K288 PolarHBondContact O-N 3.45Å
285	T	52.1	Low	53.2	Low	79 Å²	79	109 Å²	109	49%	0.485	53%	0.534	S	S	.	.	H	α-helix	trans	-72	-27.5	-179.4	-44.8	0	0	0	0	112.9	T281 K289	T281-T285 PolarHBondContact O-N 3.03Å; T281-T285 PolarHBondContact O-OG1 3.46Å; T285-K289 PolarHBondContact O-N 2.74Å
286	G	51.5	Low	51.4	Low	40 Å²	40	113.1 Å²	113.1	41%	0.412	56%	0.561	S	S	.	*	H	α-helix	trans	-68.8	-34.1	173.5	0	0	0	0	0	113.4	R282 S284	R282-G286 PolarHBondContact O-N 3.09Å; S284-G286 VanDerWaalsContact C-N 3.34Å; S284-G286 PolarHBondContact O-N 3.1Å
287	Q	50.5	Low	50.1	Low	149 Å²	149	114.9 Å²	114.9	70%	0.696	57%	0.569	S	S	*	*	H	α-helix	trans	-76.6	-41.4	173.1	-75.9	-171.4	-14.8	0	0	112.3	F283 S284 K289 K290 A291	F283-Q287 PolarHBondContact O-N 3.01Å; S284-Q287 PolarHBondContact O-N 3.21Å; Q287-K289 VanDerWaalsContact C-N 3.32Å; Q287-K289 PolarHBondContact O-N 3.08Å; Q287-K290 PolarHBondContact O-N 2.94Å; Q287-A291 PolarHBondContact O-N 3.13Å
288	K	47.9	Very low	49.2	Very low	149 Å²	149	113.7 Å²	113.7	65%	0.648	57%	0.57	S	S	*	*	H	α-helix	trans	-61.6	-34.4	178.6	-72.5	-175	179.7	-174.2	0	113.4	S284 A291 R292	S284-K288 PolarHBondContact O-N 3.45Å; K288-A291 PolarHBondContact O-N 3.2Å; K288-R292 PolarHBondContact O-N 3.05Å; K288-R292 VanDerWaalsContact O-N 3.07Å
289	K	48.8	Very low	48.1	Very low	163 Å²	163	118.8 Å²	118.8	71%	0.709	60%	0.6	S	S	*	*	H	α-helix	trans	-70.8	-30.4	173.3	-77.3	-171.5	176.3	-173.2	0	113.6	T285 Q287 K293	T285-K289 PolarHBondContact O-N 2.74Å; Q287-K289 VanDerWaalsContact C-N 3.32Å; Q287-K289 PolarHBondContact O-N 3.08Å; K289-K293 PolarHBondContact O-N 3.33Å
290	K	48.5	Very low	47.2	Very low	167 Å²	167	122.2 Å²	122.2	73%	0.726	63%	0.625	S	S	*	*	H	α-helix	trans	-73.3	-36.6	173.3	-72.3	-175.8	178.2	-173.4	0	111.9	Q287 K294	Q287-K290 PolarHBondContact O-N 2.94Å; K290-K294 PolarHBondContact O-N 2.79Å
291	A	47.2	Very low	46	Very low	61 Å²	61	127.3 Å²	127.3	50%	0.504	65%	0.648	S	S	.	*	H	α-helix	trans	-68.2	-40.9	175.7	0	0	0	0	0	112.7	Q287 K288 K294 K295	Q287-A291 PolarHBondContact O-N 3.13Å; K288-A291 PolarHBondContact O-N 3.2Å; A291-K294 PolarHBondContact O-N 3.27Å; A291-K295 PolarHBondContact O-N 2.77Å
292	R	45	Very low	44.8	Very low	198 Å²	198	132 Å²	132	75%	0.747	67%	0.665	S	S	*	*	H	α-helix	trans	-68.9	-34.3	178.6	-165.5	170.3	171.9	174.1	-3.3	112.8	K288 K294 K295 T296	K288-R292 PolarHBondContact O-N 3.05Å; K288-R292 VanDerWaalsContact O-N 3.07Å; R292-K294 VanDerWaalsContact C-N 3.28Å; R292-K294 PolarHBondContact O-N 3.4Å; R292-K295 PolarHBondContact O-N 2.77Å; R292-T296 PolarHBondContact O-N 3.02Å; R292-T296 PolarHBondContact O-OG1 2.96Å
293	K	44.8	Very low	43.7	Very low	164 Å²	164	135.6 Å²	135.6	71%	0.713	69%	0.685	S	S	*	*	H	α-helix	trans	-71.6	-20.9	175.2	-150.1	178.1	-174.8	-173.6	0	113.3	K289	K289-K293 PolarHBondContact O-N 3.33Å
294	K	44.1	Very low	42.7	Very low	172 Å²	172	134.8 Å²	134.8	75%	0.748	69%	0.693	S	S	*	*	H	α-helix	trans	-81.9	-26.6	175	-145.4	178.6	-176.7	-171.7	0	112.6	K290 A291 R292 S298	K290-K294 PolarHBondContact O-N 2.79Å; A291-K294 PolarHBondContact O-N 3.27Å; R292-K294 VanDerWaalsContact C-N 3.28Å; R292-K294 PolarHBondContact O-N 3.4Å; K294-S298 PolarHBondContact O-OG 2.68Å; K294-S298 VanDerWaalsContact O-OG 3.12Å
295	K	40.9	Very low	42.2	Very low	172 Å²	172	137.9 Å²	137.9	75%	0.748	71%	0.71	S	S	*	*	H	α-helix	trans	-85.3	-19.9	177.6	-81.6	-169	172.7	-169.3	0	115.1	A291 R292 I297	A291-K295 PolarHBondContact O-N 2.77Å; R292-K295 PolarHBondContact O-N 2.77Å; K295-I297 VanDerWaalsContact C-N 3.32Å
296	T	34.9	Very low	41	Very low	116 Å²	116	141.7 Å²	141.7	71%	0.712	73%	0.728	S	S	*	*	T	Hydrogen-bonded Turn	trans	-84	-4.4	177.4	-50.3	0	0	0	0	113.2	R292	R292-T296 PolarHBondContact O-N 3.02Å; R292-T296 PolarHBondContact O-OG1 2.96Å
297	I	45.5	Very low	40.2	Very low	147 Å²	147	147.3 Å²	147.3	75%	0.754	75%	0.745	S	S	*	*	T	Hydrogen-bonded Turn	trans	-104.9	7.9	179.1	-58.9	174.7	0	0	0	111.5	K295	K295-I297 VanDerWaalsContact C-N 3.32Å
298	S	41.5	Very low	39.4	Very low	80 Å²	80	145 Å²	145	56%	0.559	75%	0.746	S	S	*	*	S	Bend	trans	-123.3	24.7	-172	22	0	0	0	0	114.5	K294	K294-S298 PolarHBondContact O-OG 2.68Å; K294-S298 VanDerWaalsContact O-OG 3.12Å
299	L	40.4	Very low	38.7	Very low	159 Å²	159	147.1 Å²	147.1	83%	0.832	76%	0.758	S	S	*	*			trans	-141.2	67.8	178.1	-141.7	84.6	0	0	0	112.9
300	T	39.7	Very low	38.3	Very low	144 Å²	144	143.4 Å²	143.4	88%	0.883	77%	0.766	S	S	*	*			trans	-164.9	81.1	152.8	10.6	0	0	0	0	109.3
301	T	32.5	Very low	37.8	Very low	148 Å²	148	141.5 Å²	141.5	91%	0.908	77%	0.773	S	S	*	*			trans	-153.5	102.2	154.3	-39.3	0	0	0	0	108.7
302	Q	31.4	Very low	37.3	Very low	167 Å²	167	142.1 Å²	142.1	78%	0.78	79%	0.786	S	S	*	*			trans	-144.6	103.6	157.9	-156.3	169.4	-1.3	0	0	108.9
303	E	30.4	Very low	36.9	Very low	157 Å²	157	136.5 Å²	136.5	73%	0.734	79%	0.789	S	S	*	*			trans	63.4	117.3	139.5	-66.1	176.4	144.1	0	0	120.3
304	T	28.7	Very low	36.4	Very low	141 Å²	141	139.8 Å²	139.8	87%	0.865	80%	0.797	S	S	*	*				-171	150.1	102.2	37.9	0	0	0	0	111
305	T	39.4	Very low	35.9	Very low	123 Å²	123	139.1 Å²	139.1	76%	0.755	80%	0.802	S	S	*	*			trans	-56	141.8	-178	42.1	0	0	0	0	116.6
306	D	27.3	Very low	35.8	Very low	158 Å²	158	136.5 Å²	136.5	85%	0.845	80%	0.8	S	S	*	*				175	170.3	114.1	-98.1	-19.1	0	0	0	114.4
307	M	34.1	Very low	35.9	Very low	159 Å²	159	136.6 Å²	136.6	78%	0.783	80%	0.8	S	S	*	*			trans	-80.6	156.2	-148.2	-154.9	48.1	57.2	0	0	117.1
308	S	33.8	Very low	35.7	Very low	101 Å²	101	138.2 Å²	138.2	71%	0.706	80%	0.802	S	S	*	*			trans	90.5	140.2	146.4	78.8	0	0	0	0	122.4
309	Q	32.9	Very low	35.8	Very low	193 Å²	193	136.8 Å²	136.8	90%	0.902	80%	0.8	S	S	*	*			trans	78.5	103.8	162.5	-62.3	-167.3	1.1	0	0	119.3
310	G	41.6	Very low	36.5	Very low	85 Å²	85	134.3 Å²	134.3	88%	0.876	79%	0.791	S	S	*	*			trans	-82.2	130.2	163.2	0	0	0	0	0	111.9
311	S	36.9	Very low	37.2	Very low	126 Å²	126	138.8 Å²	138.8	88%	0.881	79%	0.792	S	S	*	*			trans	-168	135.7	138.8	-172	0	0	0	0	108.8
312	G	36.4	Very low	38.6	Very low	75 Å²	75	135.2 Å²	135.2	77%	0.773	77%	0.77	S	S	*	*			trans	94.1	98.8	159.1	0	0	0	0	0	117.2
313	G	37.7	Very low	41	Very low	79 Å²	79	130.3 Å²	130.3	81%	0.814	75%	0.754	S	S	*	*				100	131	126	0	0	0	0	0	118.5
314	R	34.5	Very low	43.5	Very low	233 Å²	233	127.8 Å²	127.8	88%	0.879	75%	0.749	S	S	*	*			trans	76.5	87.8	160.3	-70.3	177	155.7	137	-4.9	117	V316	R314-V316 VanDerWaalsContact C-N 3.33Å; R314-V316 PolarHBondContact O-N 3.35Å
315	N	33.8	Very low	46	Very low	159 Å²	159	125.4 Å²	125.4	85%	0.85	74%	0.738	S	S	*	*			trans	-46	99.3	135.7	-80.9	-50.4	0	0	0	109.7	V317	N315-V317 HydrophobicContact CB-CG2 4.36Å; N315-V317 PolarHBondContact O-N 3.24Å
316	V	37.5	Very low	48.2	Very low	116 Å²	116	123 Å²	123	70%	0.703	72%	0.723	S	S	*	*			trans	-76.4	75.2	163.8	-175.5	0	0	0	0	106.9	R314 F318	R314-V316 VanDerWaalsContact C-N 3.33Å; R314-V316 PolarHBondContact O-N 3.35Å; V316-F318 VanDerWaalsContact C-N 3.31Å; V316-F318 HydrophobicContact CG1-CD2 4.21Å; V316-F318 PolarHBondContact O-N 3.22Å
317	V	38.5	Very low	50.9	Low	119 Å²	119	118.5 Å²	118.5	72%	0.721	70%	0.698	S	S	*	*			trans	-64.6	101.9	158.4	174.6	0	0	0	0	104.9	N315 G319	N315-V317 HydrophobicContact CB-CG2 4.36Å; N315-V317 PolarHBondContact O-N 3.24Å; V317-G319 PolarHBondContact O-N 3.22Å
318	F	40.8	Very low	53.4	Low	181 Å²	181	114.2 Å²	114.2	79%	0.794	68%	0.678	S	S	*	*			trans	-70.2	63	167.1	-138.4	-87.6	0	0	0	108.4	V316 V320	V316-F318 VanDerWaalsContact C-N 3.31Å; V316-F318 HydrophobicContact CG1-CD2 4.21Å; V316-F318 PolarHBondContact O-N 3.22Å; F318-V320 VanDerWaalsContact C-N 3.33Å; F318-V320 HydrophobicContact CD1-CG2 4.12Å; F318-V320 PolarHBondContact O-N 3.39Å
319	G	43.9	Very low	56	Low	50 Å²	50	112 Å²	112	52%	0.515	67%	0.665	S	S	.	*			trans	-67.9	97.8	168.9	0	0	0	0	0	105.8	V317 R321	V317-G319 PolarHBondContact O-N 3.22Å; G319-R321 PolarHBondContact O-N 3.48Å
320	V	54.2	Low	58.5	Low	107 Å²	107	108 Å²	108	65%	0.648	65%	0.65	S	S	*	*			trans	-64.9	79.7	167.5	-174.3	0	0	0	0	106.5	F318 T322	F318-V320 VanDerWaalsContact C-N 3.33Å; F318-V320 HydrophobicContact CD1-CG2 4.12Å; F318-V320 PolarHBondContact O-N 3.39Å; V320-T322 HydrophobicContact CG1-CG2 3.77Å; V320-T322 PolarHBondContact O-N 3.4Å
321	R	55.2	Low	60.7	Low	238 Å²	238	112.6 Å²	112.6	90%	0.898	64%	0.641	S	S	*	*			trans	-67.2	80	159.8	-81.8	-175.9	171	-172.2	-1.6	104.9	G319 S323	G319-R321 PolarHBondContact O-N 3.48Å; R321-S323 PolarHBondContact O-N 3.46Å
322	T	62.6	Low	63.1	Low	73 Å²	73	114.3 Å²	114.3	45%	0.448	63%	0.628	S	S	.	*			trans	-52.6	112.2	166.3	42.1	0	0	0	0	106	V320 V324 I327	V320-T322 HydrophobicContact CG1-CG2 3.77Å; V320-T322 PolarHBondContact O-N 3.4Å; T322-V324 PolarHBondContact O-N 3.36Å; T322-I327 WeakPolarHBondContact O-CD1 3.47Å
323	S	80.8	Confident	65.4	Low	63 Å²	63	113 Å²	113	44%	0.441	61%	0.61	S	S	.	*			trans	-53.4	144.2	-176.2	53.7	0	0	0	0	109.6	R321 S325 V326 I327	R321-S323 PolarHBondContact O-N 3.46Å; S323-S325 PolarHBondContact O-N 3.36Å; S323-V326 WeakPolarHBondContact O-CA 3.36Å; S323-V326 WeakPolarHBondContact O-CB 3.35Å; S323-V326 PolarHBondContact O-N 3.38Å; S323-V326 VanDerWaalsContact OG-CG2 3.28Å; S323-V326 WeakPolarHBondContact OG-CG2 3.26Å; S323-I327 PolarHBondContact O-N 3.38Å; S323-I327 VanDerWaalsContact O-N 3.09Å
324	V	82.8	Confident	67.7	Low	105 Å²	105	113.4 Å²	113.4	64%	0.636	60%	0.596	S	S	*	*	H	α-helix	trans	-51.1	-34.9	-178.6	176.2	0	0	0	0	110.8	T322 I327 I328	T322-V324 PolarHBondContact O-N 3.36Å; V324-I327 PolarHBondContact O-N 3.29Å; V324-I328 HydrophobicContact CG1-CD1 3.74Å; V324-I328 HydrophobicContact CG1-CG1 4.3Å; V324-I328 WeakPolarHBondContact O-CB 3.27Å; V324-I328 VanDerWaalsContact O-CG1 3.24Å; V324-I328 WeakPolarHBondContact O-CG1 3.46Å; V324-I328 PolarHBondContact O-N 3.31Å
325	S	81.1	Confident	70.2	Confident	90 Å²	90	108.8 Å²	108.8	63%	0.629	58%	0.583	S	S	*	*	H	α-helix	trans	-60.3	-42.6	173.2	-52.9	0	0	0	0	114	S323 I328 A329	S323-S325 PolarHBondContact O-N 3.36Å; S325-I328 PolarHBondContact O-N 3.47Å; S325-A329 VanDerWaalsContact O-CB 3.25Å; S325-A329 WeakPolarHBondContact O-CB 3.46Å; S325-A329 PolarHBondContact O-N 3.19Å
326	V	85.1	Confident	72.4	Confident	73 Å²	73	107.9 Å²	107.9	44%	0.442	57%	0.567	S	S	.	*	H	α-helix	trans	-67.4	-41.4	175.3	172.1	0	0	0	0	110.4	S323 I328 A329 L330	S323-V326 WeakPolarHBondContact O-CA 3.36Å; S323-V326 WeakPolarHBondContact O-CB 3.35Å; S323-V326 PolarHBondContact O-N 3.38Å; S323-V326 VanDerWaalsContact OG-CG2 3.28Å; S323-V326 WeakPolarHBondContact OG-CG2 3.26Å; V326-I328 PolarHBondContact O-N 2.67Å; V326-A329 PolarHBondContact O-N 3.45Å; V326-L330 WeakPolarHBondContact O-CB 3.36Å; V326-L330 PolarHBondContact O-N 2.96Å
327	I	84.7	Confident	74.3	Confident	63 Å²	63	106.1 Å²	106.1	32%	0.323	55%	0.551	S	S	.	*	H	α-helix	trans	-62.2	-45.7	176.4	-60.9	173.7	0	0	0	110.4	T322 S323 V324 L330 R331	T322-I327 WeakPolarHBondContact O-CD1 3.47Å; S323-I327 PolarHBondContact O-N 3.38Å; S323-I327 VanDerWaalsContact O-N 3.09Å; V324-I327 PolarHBondContact O-N 3.29Å; I327-L330 PolarHBondContact O-N 3.45Å; I327-R331 HydrophobicContact CG2-CG 4.46Å; I327-R331 WeakPolarHBondContact O-CB 3.48Å; I327-R331 VanDerWaalsContact O-CG 3.28Å; I327-R331 WeakPolarHBondContact O-CG 3.31Å; I327-R331 PolarHBondContact O-N 2.91Å
328	I	86.3	Confident	76.3	Confident	70 Å²	70	109 Å²	109	36%	0.359	55%	0.549	S	S	.	.	H	α-helix	trans	-64.4	-45.3	177.8	-69.2	169	0	0	0	110.7	V324 S325 V326 L330 R331 R332	V324-I328 HydrophobicContact CG1-CD1 3.74Å; V324-I328 HydrophobicContact CG1-CG1 4.3Å; V324-I328 WeakPolarHBondContact O-CB 3.27Å; V324-I328 VanDerWaalsContact O-CG1 3.24Å; V324-I328 WeakPolarHBondContact O-CG1 3.46Å; V324-I328 PolarHBondContact O-N 3.31Å; S325-I328 PolarHBondContact O-N 3.47Å; V326-I328 PolarHBondContact O-N 2.67Å; I328-L330 VanDerWaalsContact C-N 3.34Å; I328-L330 PolarHBondContact O-N 3.42Å; I328-R331 PolarHBondContact O-N 3.11Å; I328-R332 HydrophobicContact CG2-CG 4.43Å; I328-R332 WeakPolarHBondContact O-CB 3.33Å; I328-R332 VanDerWaalsContact O-CG 3.29Å; I328-R332 WeakPolarHBondContact O-CG 3.45Å; I328-R332 PolarHBondContact O-N 3.34Å
329	A	87.9	Confident	78.1	Confident	53 Å²	53	104.2 Å²	104.2	44%	0.438	53%	0.529	S	S	.	.	H	α-helix	trans	-61	-43.2	177.6	0	0	0	0	0	111.7	S325 V326 R332 A333	S325-A329 VanDerWaalsContact O-CB 3.25Å; S325-A329 WeakPolarHBondContact O-CB 3.46Å; S325-A329 PolarHBondContact O-N 3.19Å; V326-A329 PolarHBondContact O-N 3.45Å; A329-R332 PolarHBondContact O-N 3.23Å; A329-A333 WeakPolarHBondContact O-CB 3.32Å; A329-A333 PolarHBondContact O-N 3.4Å
330	L	87.5	Confident	79.6	Confident	111 Å²	111	109.5 Å²	109.5	58%	0.581	53%	0.534	S	S	*	.	H	α-helix	trans	-68.7	-41.6	178.9	-159.1	141.4	0	0	0	111.2	V326 I327 I328 R332 A333 V334	V326-L330 WeakPolarHBondContact O-CB 3.36Å; V326-L330 PolarHBondContact O-N 2.96Å; I327-L330 PolarHBondContact O-N 3.45Å; I328-L330 VanDerWaalsContact C-N 3.34Å; I328-L330 PolarHBondContact O-N 3.42Å; L330-R332 PolarHBondContact O-N 2.94Å; L330-A333 PolarHBondContact O-N 2.99Å; L330-V334 HydrophobicContact CD2-CG2 4.01Å; L330-V334 WeakPolarHBondContact O-CB 3.25Å; L330-V334 VanDerWaalsContact O-CG2 3.23Å; L330-V334 WeakPolarHBondContact O-CG2 3.06Å; L330-V334 PolarHBondContact O-N 3.04Å
331	R	85.8	Confident	80.6	Confident	181 Å²	181	108.4 Å²	108.4	68%	0.683	52%	0.518	S	S	*	.	H	α-helix	trans	-59.9	-43.7	171.4	-75.9	-180	-176	-162.4	2.9	111.7	I327 I328 V334 K335	I327-R331 HydrophobicContact CG2-CG 4.46Å; I327-R331 WeakPolarHBondContact O-CB 3.48Å; I327-R331 VanDerWaalsContact O-CG 3.28Å; I327-R331 WeakPolarHBondContact O-CG 3.31Å; I327-R331 PolarHBondContact O-N 2.91Å; I328-R331 PolarHBondContact O-N 3.11Å; R331-V334 PolarHBondContact O-N 3.43Å; R331-K335 VanDerWaalsContact O-CB 3.23Å; R331-K335 WeakPolarHBondContact O-CB 3.09Å; R331-K335 PolarHBondContact O-N 3.37Å
332	R	87.9	Confident	81.7	Confident	162 Å²	162	100.3 Å²	100.3	61%	0.611	49%	0.49	S	S	*	.	H	α-helix	trans	-64.1	-40.4	175.9	-73.1	176	-173	168.4	3.7	111.9	I328 A329 L330 R336	I328-R332 HydrophobicContact CG2-CG 4.43Å; I328-R332 WeakPolarHBondContact O-CB 3.33Å; I328-R332 VanDerWaalsContact O-CG 3.29Å; I328-R332 WeakPolarHBondContact O-CG 3.45Å; I328-R332 PolarHBondContact O-N 3.34Å; A329-R332 PolarHBondContact O-N 3.23Å; L330-R332 PolarHBondContact O-N 2.94Å; R332-R336 WeakPolarHBondContact O-CB 3.32Å; R332-R336 WeakPolarHBondContact O-CG 3.38Å; R332-R336 PolarHBondContact O-N 2.84Å
333	A	86.1	Confident	82.3	Confident	47 Å²	47	104.6 Å²	104.6	39%	0.388	50%	0.498	S	S	.	.	H	α-helix	trans	-67.6	-45.7	177.3	0	0	0	0	0	111.8	A329 L330 R336 H337	A329-A333 WeakPolarHBondContact O-CB 3.32Å; A329-A333 PolarHBondContact O-N 3.4Å; L330-A333 PolarHBondContact O-N 2.99Å; A333-R336 PolarHBondContact O-N 3.13Å; A333-H337 VanDerWaalsContact O-CB 3.28Å; A333-H337 WeakPolarHBondContact O-CB 3.38Å; A333-H337 PolarHBondContact O-N 2.89Å
334	V	85.3	Confident	82	Confident	88 Å²	88	104.5 Å²	104.5	53%	0.533	49%	0.491	S	S	.	.	H	α-helix	trans	-61.9	-43.4	175.3	171.7	0	0	0	0	110.8	L330 R331 H337 R338	L330-V334 HydrophobicContact CD2-CG2 4.01Å; L330-V334 WeakPolarHBondContact O-CB 3.25Å; L330-V334 VanDerWaalsContact O-CG2 3.23Å; L330-V334 WeakPolarHBondContact O-CG2 3.06Å; L330-V334 PolarHBondContact O-N 3.04Å; R331-V334 PolarHBondContact O-N 3.43Å; V334-H337 PolarHBondContact O-N 2.9Å; V334-R338 WeakPolarHBondContact O-CB 3.03Å; V334-R338 PolarHBondContact O-N 2.73Å
335	K	85.9	Confident	81.7	Confident	136 Å²	136	104.8 Å²	104.8	59%	0.591	48%	0.483	S	S	*	.	H	α-helix	trans	-61.1	-51.6	175.8	-176.5	177.4	177.5	-178.3	0	111.7	R331 H337 R338 E339	R331-K335 VanDerWaalsContact O-CB 3.23Å; R331-K335 WeakPolarHBondContact O-CB 3.09Å; R331-K335 PolarHBondContact O-N 3.37Å; K335-H337 VanDerWaalsContact C-N 3.25Å; K335-H337 PolarHBondContact O-N 3.29Å; K335-R338 PolarHBondContact O-N 3.05Å; K335-E339 WeakPolarHBondContact CE-OE1 3.48Å; K335-E339 WeakPolarHBondContact CG-OE1 3.41Å; K335-E339 WeakPolarHBondContact O-CG 3.43Å; K335-E339 PolarHBondContact O-N 2.65Å
336	R	80.6	Confident	81.6	Confident	140 Å²	140	103 Å²	103	53%	0.528	46%	0.463	S	S	.	.	H	α-helix	trans	-56	-41.5	176	-84.4	-174.8	-84.7	154.5	-8.4	111.8	R332 A333 R340	R332-R336 WeakPolarHBondContact O-CB 3.32Å; R332-R336 WeakPolarHBondContact O-CG 3.38Å; R332-R336 PolarHBondContact O-N 2.84Å; A333-R336 PolarHBondContact O-N 3.13Å; R336-R340 VanDerWaalsContact O-CG 3.31Å; R336-R340 WeakPolarHBondContact O-CG 3.39Å; R336-R340 PolarHBondContact O-N 2.88Å
337	H	76.7	Confident	81.2	Confident	78 Å²	78	102 Å²	102	36%	0.361	46%	0.456	S	S	.	.	H	α-helix	trans	-70.7	-40.5	179.6	-176.8	-115.7	0	0	0	113	R282 A333 V334 K335 R340 R341	R282-H337 PolarHBondContact NH1-CE1 3.4Å; R282-H337 PolarHBondContact NH1-NE2 3.16Å; A333-H337 VanDerWaalsContact O-CB 3.28Å; A333-H337 WeakPolarHBondContact O-CB 3.38Å; A333-H337 PolarHBondContact O-N 2.89Å; V334-H337 PolarHBondContact O-N 2.9Å; K335-H337 VanDerWaalsContact C-N 3.25Å; K335-H337 PolarHBondContact O-N 3.29Å; H337-R340 PolarHBondContact O-N 3.47Å; H337-R341 PolarHBondContact CE1-NE 3.44Å; H337-R341 VanDerWaalsContact CE1-NE 3.35Å; H337-R341 PolarHBondContact CE1-NH2 3.02Å; H337-R341 VanDerWaalsContact CE1-NH2 3.27Å; H337-R341 PolarHBondContact O-N 2.7Å; H337-R341 VanDerWaalsContact O-N 3.1Å
338	R	80.9	Confident	80.9	Confident	179 Å²	179	100 Å²	100	68%	0.675	45%	0.445	S	S	*	.	H	α-helix	trans	-59.9	-47.8	172.2	-175.8	178.7	-179	-177	1.8	110.5	V334 K335 R340 R341 E342	V334-R338 WeakPolarHBondContact O-CB 3.03Å; V334-R338 PolarHBondContact O-N 2.73Å; K335-R338 PolarHBondContact O-N 3.05Å; R338-R340 VanDerWaalsContact C-N 3.34Å; R338-R340 PolarHBondContact O-N 3.1Å; R338-R341 PolarHBondContact O-N 3.24Å; R338-R341 VanDerWaalsContact O-N 3.15Å; R338-E342 HydrophobicContact CG-CG 4.43Å; R338-E342 WeakPolarHBondContact O-CG 3.18Å; R338-E342 PolarHBondContact O-N 3.39Å
339	E	78	Confident	80.6	Confident	81 Å²	81	101.4 Å²	101.4	38%	0.379	45%	0.446	S	S	.	.	H	α-helix	trans	-59.6	-41.6	178	-73.4	177	-169.3	0	0	112.6	K335 E342 R343	K335-E339 WeakPolarHBondContact CE-OE1 3.48Å; K335-E339 WeakPolarHBondContact CG-OE1 3.41Å; K335-E339 WeakPolarHBondContact O-CG 3.43Å; K335-E339 PolarHBondContact O-N 2.65Å; E339-E342 PolarHBondContact O-N 2.84Å; E339-R343 VanDerWaalsContact O-CG 3.28Å; E339-R343 WeakPolarHBondContact O-CG 3.18Å; E339-R343 PolarHBondContact O-N 3.4Å
340	R	76.6	Confident	80.3	Confident	162 Å²	162	99.9 Å²	99.9	61%	0.611	43%	0.431	S	S	*	.	H	α-helix	trans	-60.2	-44.3	174.1	-74.5	173.8	-176.7	173.4	-0.7	111.9	R336 H337 R338 R343 Q344	R336-R340 VanDerWaalsContact O-CG 3.31Å; R336-R340 WeakPolarHBondContact O-CG 3.39Å; R336-R340 PolarHBondContact O-N 2.88Å; H337-R340 PolarHBondContact O-N 3.47Å; R338-R340 VanDerWaalsContact C-N 3.34Å; R338-R340 PolarHBondContact O-N 3.1Å; R340-R343 PolarHBondContact O-N 2.74Å; R340-Q344 WeakPolarHBondContact O-CG 3.42Å; R340-Q344 PolarHBondContact O-N 3.38Å
341	R	74.9	Confident	80	Confident	83 Å²	83	94.6 Å²	94.6	31%	0.313	40%	0.403	S	S	.	.	H	α-helix	trans	-65.9	-42.6	177.6	-68.6	-163	-160.3	-171.5	18.6	112.6	R282 H337 R338 R343 Q344 K345	R282-R341 VanDerWaalsContact CD-CZ 3.48Å; R282-R341 VanDerWaalsContact CZ-CZ 3.47Å; R282-R341 VanDerWaalsContact NH1-NE 3.19Å; H337-R341 PolarHBondContact CE1-NE 3.44Å; H337-R341 VanDerWaalsContact CE1-NE 3.35Å; H337-R341 PolarHBondContact CE1-NH2 3.02Å; H337-R341 VanDerWaalsContact CE1-NH2 3.27Å; H337-R341 PolarHBondContact O-N 2.7Å; H337-R341 VanDerWaalsContact O-N 3.1Å; R338-R341 PolarHBondContact O-N 3.24Å; R338-R341 VanDerWaalsContact O-N 3.15Å; R341-R343 VanDerWaalsContact C-N 3.28Å; R341-R343 PolarHBondContact O-N 3.37Å; R341-Q344 PolarHBondContact O-N 2.9Å; R341-K345 WeakPolarHBondContact O-CG 3.17Å; R341-K345 PolarHBondContact O-N 2.66Å
342	E	77.7	Confident	79.8	Confident	68 Å²	68	89.8 Å²	89.8	32%	0.318	39%	0.39	S	S	.	.	H	α-helix	trans	-62.1	-38.3	177.3	-71.5	-58	144.2	0	0	111.6	R338 E339 R346	R338-E342 HydrophobicContact CG-CG 4.43Å; R338-E342 WeakPolarHBondContact O-CG 3.18Å; R338-E342 PolarHBondContact O-N 3.39Å; E339-E342 PolarHBondContact O-N 2.84Å; E342-R346 VanDerWaalsContact O-CB 3.31Å; E342-R346 WeakPolarHBondContact O-CB 3.17Å; E342-R346 PolarHBondContact O-N 2.91Å
343	R	76.3	Confident	79.8	Confident	163 Å²	163	85.1 Å²	85.1	62%	0.615	38%	0.377	S	S	*	.	H	α-helix	trans	-63.1	-48.3	172.1	-70.6	175.4	-166.9	-142.8	7.6	111.2	E339 R340 R341 K345 R346 V347	E339-R343 VanDerWaalsContact O-CG 3.28Å; E339-R343 WeakPolarHBondContact O-CG 3.18Å; E339-R343 PolarHBondContact O-N 3.4Å; R340-R343 PolarHBondContact O-N 2.74Å; R341-R343 VanDerWaalsContact C-N 3.28Å; R341-R343 PolarHBondContact O-N 3.37Å; R343-K345 PolarHBondContact O-N 2.88Å; R343-R346 PolarHBondContact O-N 3.14Å; R343-V347 WeakPolarHBondContact O-CB 3.34Å; R343-V347 VanDerWaalsContact O-CG2 3.25Å; R343-V347 WeakPolarHBondContact O-CG2 3.42Å; R343-V347 PolarHBondContact O-N 3.08Å
344	Q	74.7	Confident	79.7	Confident	62 Å²	62	82.9 Å²	82.9	29%	0.29	36%	0.359	S	S	.	.	H	α-helix	trans	-59.3	-47.3	177.5	-75.9	-176.3	-23.8	0	0	112.5	R340 R341 R346 V347 F348	R340-Q344 WeakPolarHBondContact O-CG 3.42Å; R340-Q344 PolarHBondContact O-N 3.38Å; R341-Q344 PolarHBondContact O-N 2.9Å; Q344-R346 VanDerWaalsContact C-N 3.33Å; Q344-R346 PolarHBondContact O-N 2.94Å; Q344-V347 PolarHBondContact O-N 3.33Å; Q344-F348 WeakPolarHBondContact O-CB 3.22Å; Q344-F348 PolarHBondContact O-N 2.94Å
345	K	76.3	Confident	79.8	Confident	110 Å²	110	79.2 Å²	79.2	48%	0.478	34%	0.336	S	S	.	.	H	α-helix	trans	-61	-41.3	176.9	-75.7	-174.6	175.4	-172	0	112.2	R341 R343 F348 R349	R341-K345 WeakPolarHBondContact O-CG 3.17Å; R341-K345 PolarHBondContact O-N 2.66Å; R343-K345 PolarHBondContact O-N 2.88Å; K345-F348 PolarHBondContact O-N 3.07Å; K345-R349 VanDerWaalsContact O-CB 3.29Å; K345-R349 WeakPolarHBondContact O-CB 3.28Å; K345-R349 PolarHBondContact O-N 3.05Å
346	R	78.8	Confident	79.9	Confident	54 Å²	54	75.3 Å²	75.3	20%	0.204	33%	0.326	C	S	.	.	H	α-helix	trans	-62.3	-48.9	177.4	-173.6	-166.8	-54.4	-178.9	7.6	110.9	E342 R343 Q344 F348 R349 M350 T406	E342-R346 VanDerWaalsContact O-CB 3.31Å; E342-R346 WeakPolarHBondContact O-CB 3.17Å; E342-R346 PolarHBondContact O-N 2.91Å; R343-R346 PolarHBondContact O-N 3.14Å; Q344-R346 VanDerWaalsContact C-N 3.33Å; Q344-R346 PolarHBondContact O-N 2.94Å; R346-F348 VanDerWaalsContact C-N 3.33Å; R346-F348 PolarHBondContact O-N 3.35Å; R346-R349 PolarHBondContact O-N 3.09Å; R346-M350 WeakPolarHBondContact O-CB 3.37Å; R346-M350 PolarHBondContact O-N 3.15Å; R346-T406 WeakPolarHBondContact CD-O 3.26Å; R346-T406 WeakPolarHBondContact CG-O 3.35Å
347	V	77.2	Confident	80.3	Confident	50 Å²	50	69.6 Å²	69.6	30%	0.303	31%	0.306	S	S	.	.	H	α-helix	trans	-62	-41.5	179.9	170.3	0	0	0	0	110.9	R343 Q344 M350 S351	R343-V347 WeakPolarHBondContact O-CB 3.34Å; R343-V347 VanDerWaalsContact O-CG2 3.25Å; R343-V347 WeakPolarHBondContact O-CG2 3.42Å; R343-V347 PolarHBondContact O-N 3.08Å; Q344-V347 PolarHBondContact O-N 3.33Å; V347-M350 WeakPolarHBondContact O-CB 3.02Å; V347-S351 PolarHBondContact O-N 3.11Å; V347-S351 VanDerWaalsContact O-N 3.1Å; V347-S351 PolarHBondContact O-OG 2.86Å
348	F	77.9	Confident	81	Confident	21 Å²	21	66 Å²	66	9%	0.092	29%	0.289	C	S	.	.	H	α-helix	trans	-63.7	-52	173.9	173.7	-104.6	0	0	0	112.9	Y268 I271 L272 L275 Q344 K345 R346 M350 S351 L352	Y268-F348 AromaticContact CD1-CE2 3.73Å; Y268-F348 HydrophobicContact CD1-CE2 3.73Å; Y268-F348 HydrophobicContact CD1-CZ 4.06Å; Y268-F348 HydrophobicContact CE1-CD2 4.27Å; Y268-F348 AromaticContact CE1-CE2 3.55Å; Y268-F348 HydrophobicContact CE1-CE2 3.55Å; Y268-F348 HydrophobicContact CE1-CZ 4.14Å; I271-F348 HydrophobicContact CB-CD2 4.5Å; I271-F348 HydrophobicContact CB-CE2 3.94Å; I271-F348 HydrophobicContact CG2-CD2 3.38Å; I271-F348 HydrophobicContact CG2-CE2 3.21Å; I271-F348 HydrophobicContact CG2-CG 4.43Å; I271-F348 HydrophobicContact CG2-CZ 4.15Å; L272-F348 HydrophobicContact CD2-CE1 3.68Å; L272-F348 HydrophobicContact CD2-CZ 3.44Å; L272-F348 VanDerWaalsContact CD2-CZ 3.44Å; L272-F348 HydrophobicContact CG-CZ 3.92Å; L275-F348 HydrophobicContact CD1-CB 4.33Å; L275-F348 HydrophobicContact CD1-CD1 3.55Å; L275-F348 HydrophobicContact CD1-CD2 3.91Å; L275-F348 HydrophobicContact CD1-CE1 3.77Å; L275-F348 HydrophobicContact CD1-CE2 4.11Å; L275-F348 HydrophobicContact CD1-CG 3.62Å; L275-F348 HydrophobicContact CD1-CZ 4.04Å; Q344-F348 WeakPolarHBondContact O-CB 3.22Å; Q344-F348 PolarHBondContact O-N 2.94Å; K345-F348 PolarHBondContact O-N 3.07Å; R346-F348 VanDerWaalsContact C-N 3.33Å; R346-F348 PolarHBondContact O-N 3.35Å; F348-M350 PolarHBondContact O-N 3.01Å; F348-S351 PolarHBondContact O-N 3.23Å; F348-S351 VanDerWaalsContact O-N 3.11Å; F348-L352 PolarHBondContact O-N 2.96Å
349	R	80.7	Confident	81.5	Confident	100 Å²	100	59.3 Å²	59.3	38%	0.377	27%	0.267	S	S	.	.	H	α-helix	trans	-55.9	-39.7	178.6	177.9	-179.5	65.8	-159.8	5.8	111.5	K345 R346 L352 L353	K345-R349 VanDerWaalsContact O-CB 3.29Å; K345-R349 WeakPolarHBondContact O-CB 3.28Å; K345-R349 PolarHBondContact O-N 3.05Å; R346-R349 PolarHBondContact O-N 3.09Å; R349-L352 WeakPolarHBondContact O-CB 3.19Å; R349-L352 PolarHBondContact O-N 3.16Å; R349-L353 WeakPolarHBondContact O-CG 3.24Å; R349-L353 PolarHBondContact O-N 3.46Å
350	M	80.8	Confident	82.2	Confident	22 Å²	22	61.1 Å²	61.1	11%	0.108	28%	0.279	C	S	.	.	H	α-helix	trans	-64.2	-45.5	178.2	175.9	176.2	-168.8	0	0	112.5	R346 V347 F348 L352 L353 I354 Y403 T406	R346-M350 WeakPolarHBondContact O-CB 3.37Å; R346-M350 PolarHBondContact O-N 3.15Å; V347-M350 WeakPolarHBondContact O-CB 3.02Å; F348-M350 PolarHBondContact O-N 3.01Å; M350-L352 VanDerWaalsContact C-N 3.31Å; M350-L352 PolarHBondContact O-N 3.25Å; M350-L353 WeakPolarHBondContact O-CB 3.39Å; M350-L353 PolarHBondContact O-N 2.99Å; M350-I354 HydrophobicContact CG-CD1 4.49Å; M350-I354 WeakPolarHBondContact O-CG1 3.32Å; M350-I354 PolarHBondContact O-N 3.32Å; M350-I354 VanDerWaalsContact O-N 3.08Å; M350-Y403 HydrophobicContact CE-CD1 2.84Å; M350-Y403 HydrophobicContact CE-CD2 3.53Å; M350-Y403 HydrophobicContact CE-CE1 3.06Å; M350-Y403 HydrophobicContact CE-CE2 3.78Å; M350-Y403 HydrophobicContact CE-CG 3.01Å; M350-Y403 HydrophobicContact SD-CD1 4.29Å; M350-Y403 HydrophobicContact SD-CE1 4.29Å; M350-T406 HydrophobicContact CB-CG2 4.2Å; M350-T406 HydrophobicContact CG-CG2 4.33Å
351	S	80.3	Confident	83	Confident	0 Å²	0	53.8 Å²	53.8	0%	0	25%	0.252	C	S	.	.	H	α-helix	trans	-68.5	-30.7	175.4	-61.6	0	0	0	0	113	R177 Y268 V347 F348 L353 I354 I355	R177-S351 WeakPolarHBondContact CD-OG 3.21Å; R177-S351 VanDerWaalsContact CG-OG 3.31Å; R177-S351 WeakPolarHBondContact CG-OG 3.26Å; R177-S351 PolarHBondContact NE-OG 3.36Å; Y268-S351 VanDerWaalsContact OH-C 3.23Å; Y268-S351 WeakPolarHBondContact OH-CB 3.43Å; Y268-S351 PolarHBondContact OH-O 3.23Å; V347-S351 PolarHBondContact O-N 3.11Å; V347-S351 VanDerWaalsContact O-N 3.1Å; V347-S351 PolarHBondContact O-OG 2.86Å; F348-S351 PolarHBondContact O-N 3.23Å; F348-S351 VanDerWaalsContact O-N 3.11Å; S351-L353 VanDerWaalsContact C-N 3.32Å; S351-L353 PolarHBondContact O-N 3.18Å; S351-I354 PolarHBondContact O-N 3.37Å; S351-I355 VanDerWaalsContact O-CG1 3.3Å; S351-I355 WeakPolarHBondContact O-CG1 3.5Å; S351-I355 PolarHBondContact O-N 3.35Å; S351-I355 VanDerWaalsContact O-N 3.1Å
352	L	83.3	Confident	83.8	Confident	79 Å²	79	50 Å²	50	41%	0.414	24%	0.238	S	C	.	.	H	α-helix	trans	-60.3	-41.8	169.2	-178.7	68.3	0	0	0	111.8	Y268 F348 R349 M350 I355 S356	Y268-L352 HydrophobicContact CD1-CD1 4.08Å; Y268-L352 HydrophobicContact CE1-CB 4.22Å; Y268-L352 HydrophobicContact CE1-CD1 4.23Å; F348-L352 PolarHBondContact O-N 2.96Å; R349-L352 WeakPolarHBondContact O-CB 3.19Å; R349-L352 PolarHBondContact O-N 3.16Å; M350-L352 VanDerWaalsContact C-N 3.31Å; M350-L352 PolarHBondContact O-N 3.25Å; L352-I355 PolarHBondContact O-N 3.14Å; L352-S356 WeakPolarHBondContact O-CB 3.33Å; L352-S356 PolarHBondContact O-N 3.19Å
353	L	86.1	Confident	84.5	Confident	65 Å²	65	49.1 Å²	49.1	34%	0.34	24%	0.238	S	C	.	.	H	α-helix	trans	-65	-45.8	177	-70.7	167	0	0	0	111.7	R349 M350 S351 I355 S356 T357 L402 T406	R349-L353 WeakPolarHBondContact O-CG 3.24Å; R349-L353 PolarHBondContact O-N 3.46Å; M350-L353 WeakPolarHBondContact O-CB 3.39Å; M350-L353 PolarHBondContact O-N 2.99Å; S351-L353 VanDerWaalsContact C-N 3.32Å; S351-L353 PolarHBondContact O-N 3.18Å; L353-I355 PolarHBondContact O-N 3.22Å; L353-S356 PolarHBondContact O-N 3.17Å; L353-T357 WeakPolarHBondContact O-CB 3.21Å; L353-T357 PolarHBondContact O-N 3.49Å; L353-T357 PolarHBondContact O-OG1 3.03Å; L353-T357 VanDerWaalsContact O-OG1 3.12Å; L353-L402 HydrophobicContact CB-CD1 4Å; L353-L402 HydrophobicContact CB-CD2 3.9Å; L353-L402 HydrophobicContact CB-CG 4.43Å; L353-L402 HydrophobicContact CD1-CD2 4.12Å; L353-L402 HydrophobicContact CG-CD2 4.41Å; L353-T406 HydrophobicContact CD1-CG2 3.52Å
354	I	85.8	Confident	85.3	Confident	0 Å²	0	42.9 Å²	42.9	0%	0	22%	0.218	C	C	.	.	H	α-helix	trans	-54.4	-44.5	177	-67.6	167.2	0	0	0	110.6	V170 I173 M350 S351 T357 F358 L402 Y403	V170-I354 HydrophobicContact CG2-CG2 4.3Å; I173-I354 HydrophobicContact CD1-CG2 4.48Å; M350-I354 HydrophobicContact CG-CD1 4.49Å; M350-I354 WeakPolarHBondContact O-CG1 3.32Å; M350-I354 PolarHBondContact O-N 3.32Å; M350-I354 VanDerWaalsContact O-N 3.08Å; S351-I354 PolarHBondContact O-N 3.37Å; I354-T357 PolarHBondContact O-N 2.88Å; I354-F358 PolarHBondContact O-N 2.94Å; I354-L402 HydrophobicContact CG1-CD1 4.43Å; I354-Y403 HydrophobicContact CD1-CE2 3.55Å; I354-Y403 WeakPolarHBondContact CD1-OH 3.45Å; I354-Y403 HydrophobicContact CG1-CE2 4.29Å
355	I	85.8	Confident	86	Confident	11 Å²	11	40 Å²	40	6%	0.056	21%	0.205	C	C	.	.	H	α-helix	trans	-71.6	-44.1	-179	-69.8	176.3	0	0	0	112.4	V170 T174 M264 Y268 S351 L352 L353 T357 F358 L359	V170-I355 HydrophobicContact CG1-CG1 3.69Å; T174-I355 VanDerWaalsContact OG1-CD1 3.24Å; T174-I355 WeakPolarHBondContact OG1-CD1 3.33Å; M264-I355 HydrophobicContact CE-CB 3.87Å; M264-I355 HydrophobicContact CE-CD1 3.89Å; M264-I355 HydrophobicContact CE-CG1 3.55Å; M264-I355 HydrophobicContact CE-CG2 3.3Å; Y268-I355 HydrophobicContact CD2-CD1 3.62Å; Y268-I355 HydrophobicContact CE1-CD1 4.05Å; Y268-I355 HydrophobicContact CE2-CD1 2.86Å; Y268-I355 HydrophobicContact CE2-CG1 4.34Å; Y268-I355 HydrophobicContact CG-CD1 4.45Å; Y268-I355 WeakPolarHBondContact OH-CD1 3.44Å; S351-I355 VanDerWaalsContact O-CG1 3.3Å; S351-I355 WeakPolarHBondContact O-CG1 3.5Å; S351-I355 PolarHBondContact O-N 3.35Å; S351-I355 VanDerWaalsContact O-N 3.1Å; L352-I355 PolarHBondContact O-N 3.14Å; L353-I355 PolarHBondContact O-N 3.22Å; I355-T357 PolarHBondContact O-N 3.34Å; I355-F358 PolarHBondContact O-N 2.97Å; I355-L359 HydrophobicContact CG2-CD1 4.06Å; I355-L359 HydrophobicContact CG2-CG 4.36Å; I355-L359 WeakPolarHBondContact O-CG 3.09Å; I355-L359 PolarHBondContact O-N 3.47Å
356	S	88	Confident	86.7	Confident	54 Å²	54	35.1 Å²	35.1	38%	0.378	18%	0.184	S	C	.	.	H	α-helix	trans	-56.5	-43.2	175.9	-172.1	0	0	0	0	110.3	L352 L353 L359 L360	L352-S356 WeakPolarHBondContact O-CB 3.33Å; L352-S356 PolarHBondContact O-N 3.19Å; L353-S356 PolarHBondContact O-N 3.17Å; S356-L359 PolarHBondContact O-N 3.31Å; S356-L360 WeakPolarHBondContact O-CB 3.47Å; S356-L360 WeakPolarHBondContact O-CD1 3.34Å; S356-L360 WeakPolarHBondContact O-CG 3.4Å; S356-L360 PolarHBondContact O-N 3.49Å
357	T	90.8	Very high	87.2	Confident	20 Å²	20	36 Å²	36	12%	0.123	20%	0.195	C	C	.	.	H	α-helix	trans	-64.7	-46.2	176	-63.3	0	0	0	0	111.9	L353 I354 I355 L359 L360 C361 T395 F398	L353-T357 WeakPolarHBondContact O-CB 3.21Å; L353-T357 PolarHBondContact O-N 3.49Å; L353-T357 PolarHBondContact O-OG1 3.03Å; L353-T357 VanDerWaalsContact O-OG1 3.12Å; I354-T357 PolarHBondContact O-N 2.88Å; I355-T357 PolarHBondContact O-N 3.34Å; T357-L359 VanDerWaalsContact C-N 3.32Å; T357-L359 PolarHBondContact O-N 2.98Å; T357-L360 PolarHBondContact O-N 2.88Å; T357-C361 WeakPolarHBondContact O-CB 3.34Å; T357-C361 PolarHBondContact O-N 3.17Å; T357-C361 PolarHBondContact O-SG 3.4Å; T357-T395 HydrophobicContact CG2-CG2 4.4Å; T357-F398 HydrophobicContact CG2-CB 3.54Å; T357-F398 HydrophobicContact CG2-CD2 3.59Å; T357-F398 HydrophobicContact CG2-CG 3.8Å
358	F	90.4	Very high	87.7	Confident	1 Å²	1	34.2 Å²	34.2	0%	0.004	18%	0.184	C	C	.	.	H	α-helix	trans	-54.4	-48.7	175	171.9	-101.3	0	0	0	111.7	T166 A167 V170 F257 M264 I354 I355 C361 W362	T166-F358 HydrophobicContact CG2-CD2 3.77Å; T166-F358 HydrophobicContact CG2-CE2 3.95Å; A167-F358 HydrophobicContact CB-CE2 4.08Å; A167-F358 HydrophobicContact CB-CZ 3.65Å; V170-F358 HydrophobicContact CG1-CB 4.34Å; V170-F358 HydrophobicContact CG1-CG 4.37Å; V170-F358 HydrophobicContact CG2-CB 4.26Å; V170-F358 HydrophobicContact CG2-CD2 4.19Å; V170-F358 HydrophobicContact CG2-CG 4.24Å; F257-F358 HydrophobicContact CD2-CE1 4.42Å; F257-F358 HydrophobicContact CD2-CZ 4.1Å; F257-F358 AromaticContact CE2-CE1 3.93Å; F257-F358 HydrophobicContact CE2-CE1 3.93Å; F257-F358 AromaticContact CE2-CZ 3.89Å; F257-F358 HydrophobicContact CE2-CZ 3.89Å; M264-F358 HydrophobicContact CE-CD1 4.01Å; M264-F358 HydrophobicContact SD-CD1 4.42Å; M264-F358 HydrophobicContact SD-CE1 4.41Å; I354-F358 PolarHBondContact O-N 2.94Å; I355-F358 PolarHBondContact O-N 2.97Å; F358-C361 PolarHBondContact O-N 3.5Å; F358-W362 HydrophobicContact CD2-CB 4.45Å; F358-W362 AromaticContact CD2-CD1 3.27Å; F358-W362 AromaticContact CD2-CG 3.95Å; F358-W362 HydrophobicContact CD2-CG 3.95Å; F358-W362 AromaticContact CD2-NE1 3.79Å; F358-W362 HydrophobicContact CE2-CB 4.13Å; F358-W362 AromaticContact CE2-CD1 3.45Å; F358-W362 VanDerWaalsContact CE2-CD1 3.45Å; F358-W362 HydrophobicContact CE2-CD2 4.32Å; F358-W362 AromaticContact CE2-CG 3.69Å; F358-W362 HydrophobicContact CE2-CG 3.69Å; F358-W362 AromaticContact CE2-NE1 3.92Å; F358-W362 HydrophobicContact CZ-CB 4.36Å; F358-W362 HydrophobicContact CZ-CG 4.37Å; F358-W362 WeakPolarHBondContact O-CB 3.08Å; F358-W362 PolarHBondContact O-N 2.95Å
359	L	90.8	Very high	88.1	Confident	39 Å²	39	33.3 Å²	33.3	20%	0.204	18%	0.18	C	C	.	.	H	α-helix	trans	-62.6	-46.5	178.4	-66.3	175.3	0	0	0	111.6	V261 I355 S356 T357 C361 T363	V261-L359 HydrophobicContact CB-CD2 4.27Å; V261-L359 HydrophobicContact CG1-CD2 3.89Å; V261-L359 HydrophobicContact CG2-CD2 3.51Å; I355-L359 HydrophobicContact CG2-CD1 4.06Å; I355-L359 HydrophobicContact CG2-CG 4.36Å; I355-L359 WeakPolarHBondContact O-CG 3.09Å; I355-L359 PolarHBondContact O-N 3.47Å; S356-L359 PolarHBondContact O-N 3.31Å; T357-L359 VanDerWaalsContact C-N 3.32Å; T357-L359 PolarHBondContact O-N 2.98Å; L359-C361 VanDerWaalsContact C-N 3.33Å; L359-C361 PolarHBondContact O-N 3.44Å; L359-T363 WeakPolarHBondContact O-CB 3.46Å; L359-T363 PolarHBondContact O-N 3.21Å; L359-T363 PolarHBondContact O-OG1 3.17Å
360	L	92.5	Very high	88.3	Confident	119 Å²	119	30.5 Å²	30.5	62%	0.623	17%	0.174	S	C	*	.	H	α-helix	trans	-63.1	-39	-178.8	-73.4	168.8	0	0	0	112.5	S356 T357 P364	S356-L360 WeakPolarHBondContact O-CB 3.47Å; S356-L360 WeakPolarHBondContact O-CD1 3.34Å; S356-L360 WeakPolarHBondContact O-CG 3.4Å; S356-L360 PolarHBondContact O-N 3.49Å; T357-L360 PolarHBondContact O-N 2.88Å; L360-P364 WeakPolarHBondContact O-CD 3.45Å; L360-P364 WeakPolarHBondContact O-CG 3.41Å
361	C	93.8	Very high	88.5	Confident	9 Å²	9	31.7 Å²	31.7	6%	0.061	18%	0.183	C	C	.	.	H	α-helix	trans	-82.3	-37.9	-176.8	-71	0	0	0	0	113.3	T357 F358 L359 M391 T395	T357-C361 WeakPolarHBondContact O-CB 3.34Å; T357-C361 PolarHBondContact O-N 3.17Å; T357-C361 PolarHBondContact O-SG 3.4Å; F358-C361 PolarHBondContact O-N 3.5Å; L359-C361 VanDerWaalsContact C-N 3.33Å; L359-C361 PolarHBondContact O-N 3.44Å; C361-M391 WeakPolarHBondContact CB-O 3.34Å; C361-M391 PolarHBondContact SG-O 3.15Å; C361-M391 VanDerWaalsContact SG-O 3.37Å; C361-T395 HydrophobicContact CB-CG2 3.36Å
362	W	92.4	Very high	88.6	Confident	3 Å²	3	31.7 Å²	31.7	1%	0.011	18%	0.183	C	C	.	.	H	α-helix	trans	-96.1	-22.5	-174.6	-71.2	89.8	0	0	0	114.4	A162 T166 F257 F358 I365 S366 A392	A162-W362 HydrophobicContact CB-CH2 4.08Å; T166-W362 HydrophobicContact CG2-CZ2 4.47Å; F257-W362 HydrophobicContact CD2-CB 4.46Å; F257-W362 HydrophobicContact CE2-CB 3.69Å; F257-W362 HydrophobicContact CZ-CB 4.41Å; F358-W362 HydrophobicContact CD2-CB 4.45Å; F358-W362 AromaticContact CD2-CD1 3.27Å; F358-W362 AromaticContact CD2-CG 3.95Å; F358-W362 HydrophobicContact CD2-CG 3.95Å; F358-W362 AromaticContact CD2-NE1 3.79Å; F358-W362 HydrophobicContact CE2-CB 4.13Å; F358-W362 AromaticContact CE2-CD1 3.45Å; F358-W362 VanDerWaalsContact CE2-CD1 3.45Å; F358-W362 HydrophobicContact CE2-CD2 4.32Å; F358-W362 AromaticContact CE2-CG 3.69Å; F358-W362 HydrophobicContact CE2-CG 3.69Å; F358-W362 AromaticContact CE2-NE1 3.92Å; F358-W362 HydrophobicContact CZ-CB 4.36Å; F358-W362 HydrophobicContact CZ-CG 4.37Å; F358-W362 WeakPolarHBondContact O-CB 3.08Å; F358-W362 PolarHBondContact O-N 2.95Å; W362-I365 HydrophobicContact CE3-CG2 4.11Å; W362-I365 WeakPolarHBondContact O-CG2 3.33Å; W362-S366 WeakPolarHBondContact O-CB 3.49Å; W362-S366 PolarHBondContact O-N 2.9Å; W362-S366 VanDerWaalsContact O-N 3.15Å; W362-S366 PolarHBondContact O-OG 2.75Å; W362-A392 HydrophobicContact CD2-CB 3.85Å; W362-A392 HydrophobicContact CE3-CB 3.83Å; W362-A392 HydrophobicContact CG-CB 4.43Å; W362-A392 HydrophobicContact CH2-CB 4.09Å; W362-A392 HydrophobicContact CZ2-CB 4.14Å; W362-A392 HydrophobicContact CZ3-CB 3.92Å
363	T	91.6	Very high	88.5	Confident	50 Å²	50	30.4 Å²	30.4	31%	0.307	18%	0.176	S	C	.	.	H	α-helix	trans	-61.8	-43.7	178.1	-57	0	0	0	0	113.1	L359 I365 S366 V367	L359-T363 WeakPolarHBondContact O-CB 3.46Å; L359-T363 PolarHBondContact O-N 3.21Å; L359-T363 PolarHBondContact O-OG1 3.17Å; T363-I365 PolarHBondContact O-N 3.28Å; T363-S366 PolarHBondContact O-N 3.31Å; T363-V367 HydrophobicContact CG2-CG2 3.86Å; T363-V367 WeakPolarHBondContact O-CB 3.5Å; T363-V367 WeakPolarHBondContact O-CG2 3.41Å; T363-V367 PolarHBondContact O-N 3.48Å
364	P	94.1	Very high	88.3	Confident	32 Å²	32	31.5 Å²	31.5	21%	0.208	19%	0.188	C	C	.	.	H	α-helix	trans	-57.9	-45.9	-178	-26.7	36.4	0	0	0	113.1	L360 L368 F388 M391	L360-P364 WeakPolarHBondContact O-CD 3.45Å; L360-P364 WeakPolarHBondContact O-CG 3.41Å; P364-L368 WeakPolarHBondContact O-CB 3.3Å; P364-L368 PolarHBondContact O-N 3.01Å; P364-F388 HydrophobicContact CB-CB 4.12Å; P364-F388 HydrophobicContact CB-CD1 3.64Å; P364-F388 HydrophobicContact CB-CD2 3.9Å; P364-F388 HydrophobicContact CB-CE1 3.96Å; P364-F388 HydrophobicContact CB-CE2 4.21Å; P364-F388 HydrophobicContact CB-CG 3.62Å; P364-F388 HydrophobicContact CB-CZ 4.25Å; P364-M391 HydrophobicContact CG-SD 4.05Å
365	I	89.7	Confident	88.2	Confident	2 Å²	2	38.3 Å²	38.3	1%	0.01	22%	0.224	C	C	.	.	H	α-helix	trans	-67.8	-40.3	177.3	-174.5	164	0	0	0	111.9	W362 T363 V367 L368 N369 F388 L389 A392	W362-I365 HydrophobicContact CE3-CG2 4.11Å; W362-I365 WeakPolarHBondContact O-CG2 3.33Å; T363-I365 PolarHBondContact O-N 3.28Å; I365-V367 PolarHBondContact O-N 2.88Å; I365-L368 PolarHBondContact O-N 2.93Å; I365-N369 WeakPolarHBondContact O-CB 3.47Å; I365-N369 VanDerWaalsContact O-CG 3.24Å; I365-N369 PolarHBondContact O-N 3.42Å; I365-F388 HydrophobicContact CB-CB 3.86Å; I365-L389 HydrophobicContact CD1-CB 3.82Å; I365-L389 HydrophobicContact CD1-CD1 3.77Å; I365-L389 HydrophobicContact CD1-CG 4.39Å; I365-A392 HydrophobicContact CG2-CB 4.21Å
366	S	89.3	Confident	87.5	Confident	7 Å²	7	38.7 Å²	38.7	5%	0.049	23%	0.23	C	C	.	.	H	α-helix	trans	-63.8	-41.2	177.5	-64	0	0	0	0	112.7	F257 W362 T363 T370	F257-S366 WeakPolarHBondContact CD1-OG 3.2Å; F257-S366 WeakPolarHBondContact CD2-OG 3.33Å; F257-S366 VanDerWaalsContact CG-OG 3.29Å; F257-S366 WeakPolarHBondContact CG-OG 3.33Å; W362-S366 WeakPolarHBondContact O-CB 3.49Å; W362-S366 PolarHBondContact O-N 2.9Å; W362-S366 VanDerWaalsContact O-N 3.15Å; W362-S366 PolarHBondContact O-OG 2.75Å; T363-S366 PolarHBondContact O-N 3.31Å; S366-T370 PolarHBondContact O-N 3.1Å; S366-T370 VanDerWaalsContact O-N 3.12Å; S366-T370 PolarHBondContact O-OG1 2.83Å
367	V	90	Very high	86.9	Confident	72 Å²	72	37.5 Å²	37.5	44%	0.436	22%	0.221	S	C	.	.	H	α-helix	trans	-65.4	-44.8	175	171.4	0	0	0	0	110	T363 I365 N369 T370 T371	T363-V367 HydrophobicContact CG2-CG2 3.86Å; T363-V367 WeakPolarHBondContact O-CB 3.5Å; T363-V367 WeakPolarHBondContact O-CG2 3.41Å; T363-V367 PolarHBondContact O-N 3.48Å; I365-V367 PolarHBondContact O-N 2.88Å; V367-N369 PolarHBondContact O-N 2.7Å; V367-T370 WeakPolarHBondContact O-CA 3.46Å; V367-T370 VanDerWaalsContact O-CB 3.3Å; V367-T370 WeakPolarHBondContact O-CB 3.43Å; V367-T370 PolarHBondContact O-N 3.34Å; V367-T370 VanDerWaalsContact O-N 3.12Å; V367-T371 PolarHBondContact O-N 3.04Å; V367-T371 PolarHBondContact O-OG1 3.23Å; V367-T371 VanDerWaalsContact O-OG1 3.12Å
368	L	88.2	Confident	86.3	Confident	13 Å²	13	38.7 Å²	38.7	7%	0.068	23%	0.231	C	C	.	.	H	α-helix	trans	-64	-41.9	179.2	-171.5	72.4	0	0	0	112.4	P364 I365 T370 T371 I372 L381 L384 R385 F388	P364-L368 WeakPolarHBondContact O-CB 3.3Å; P364-L368 PolarHBondContact O-N 3.01Å; I365-L368 PolarHBondContact O-N 2.93Å; L368-T370 PolarHBondContact O-N 3.13Å; L368-T371 CarbonylContact O-C 3.53Å; L368-T371 WeakPolarHBondContact O-CA 3.31Å; L368-T371 WeakPolarHBondContact O-CB 3.32Å; L368-T371 PolarHBondContact O-N 2.92Å; L368-I372 HydrophobicContact CG-CD1 4.19Å; L368-I372 WeakPolarHBondContact O-CG1 3.32Å; L368-I372 PolarHBondContact O-N 2.92Å; L368-L381 HydrophobicContact CD1-CG 4.1Å; L368-L384 HydrophobicContact CD1-CB 4.34Å; L368-L384 VanDerWaalsContact CD2-C 3.47Å; L368-L384 HydrophobicContact CD2-CB 3.81Å; L368-R385 HydrophobicContact CD2-CB 3.67Å; L368-R385 HydrophobicContact CD2-CG 4.44Å; L368-F388 HydrophobicContact CB-CD2 3.97Å; L368-F388 HydrophobicContact CB-CE2 4.24Å; L368-F388 HydrophobicContact CD1-CE2 4.46Å; L368-F388 HydrophobicContact CD2-CD2 3.67Å; L368-F388 HydrophobicContact CD2-CE2 4.08Å; L368-F388 HydrophobicContact CG-CD2 4.36Å
369	N	85.6	Confident	85.6	Confident	2 Å²	2	43.5 Å²	43.5	1%	0.011	26%	0.256	C	S	.	.	H	α-helix	trans	-59.2	-36.1	173.5	-74.5	-13.3	0	0	0	111.6	L250 I254 I365 V367 L373 R385	L250-N369 HydrophobicContact CD2-CB 4.06Å; I254-N369 HydrophobicContact CD1-CB 4.45Å; I365-N369 WeakPolarHBondContact O-CB 3.47Å; I365-N369 VanDerWaalsContact O-CG 3.24Å; I365-N369 PolarHBondContact O-N 3.42Å; V367-N369 PolarHBondContact O-N 2.7Å; N369-L373 WeakPolarHBondContact O-CB 3.43Å; N369-L373 PolarHBondContact O-N 3.02Å; N369-R385 PolarHBondContact OD1-NE 3.12Å
370	T	84.9	Confident	85.3	Confident	40 Å²	40	47 Å²	47	25%	0.245	28%	0.275	C	S	.	.	H	α-helix	trans	-66.6	-42	173	-51.3	0	0	0	0	111.2	S366 V367 L368 L373 C374	S366-T370 PolarHBondContact O-N 3.1Å; S366-T370 VanDerWaalsContact O-N 3.12Å; S366-T370 PolarHBondContact O-OG1 2.83Å; V367-T370 WeakPolarHBondContact O-CA 3.46Å; V367-T370 VanDerWaalsContact O-CB 3.3Å; V367-T370 WeakPolarHBondContact O-CB 3.43Å; V367-T370 PolarHBondContact O-N 3.34Å; V367-T370 VanDerWaalsContact O-N 3.12Å; L368-T370 PolarHBondContact O-N 3.13Å; T370-L373 WeakPolarHBondContact O-CB 3.26Å; T370-L373 PolarHBondContact O-N 3.06Å; T370-C374 PolarHBondContact O-N 3.46Å; T370-C374 PolarHBondContact O-SG 3.05Å
371	T	85.7	Confident	84.9	Confident	48 Å²	48	42.7 Å²	42.7	29%	0.294	25%	0.252	S	S	.	.	H	α-helix	trans	-63.6	-42.5	176.2	-54.1	0	0	0	0	111.9	V367 L368 L373 C374 L375 L381	V367-T371 PolarHBondContact O-N 3.04Å; V367-T371 PolarHBondContact O-OG1 3.23Å; V367-T371 VanDerWaalsContact O-OG1 3.12Å; L368-T371 CarbonylContact O-C 3.53Å; L368-T371 WeakPolarHBondContact O-CA 3.31Å; L368-T371 WeakPolarHBondContact O-CB 3.32Å; L368-T371 PolarHBondContact O-N 2.92Å; T371-L373 VanDerWaalsContact C-N 3.29Å; T371-L373 PolarHBondContact O-N 3.4Å; T371-C374 PolarHBondContact O-N 3.05Å; T371-C374 VanDerWaalsContact O-N 3.16Å; T371-L375 HydrophobicContact CG2-CD1 3.73Å; T371-L375 HydrophobicContact CG2-CG 4.32Å; T371-L375 WeakPolarHBondContact O-CB 3.44Å; T371-L375 PolarHBondContact O-N 2.88Å; T371-L381 HydrophobicContact CG2-CD2 4.04Å
372	I	82.4	Confident	84.2	Confident	0 Å²	0	43 Å²	43	0%	0	25%	0.254	C	S	.	.	H	α-helix	trans	-60.5	-41.2	175.3	-68.2	166.6	0	0	0	110.3	L232 L368 C374 G376 L381 R385	L232-I372 HydrophobicContact CD1-CG2 4.31Å; L368-I372 HydrophobicContact CG-CD1 4.19Å; L368-I372 WeakPolarHBondContact O-CG1 3.32Å; L368-I372 PolarHBondContact O-N 2.92Å; I372-C374 VanDerWaalsContact C-N 3.35Å; I372-C374 PolarHBondContact O-N 3.34Å; I372-G376 CarbonylContact O-C 3.57Å; I372-G376 WeakPolarHBondContact O-CA 3.39Å; I372-G376 PolarHBondContact O-N 3.35Å; I372-L381 HydrophobicContact CD1-CB 4.5Å; I372-L381 HydrophobicContact CG1-CB 4.05Å; I372-L381 HydrophobicContact CG1-CD2 3.79Å; I372-L381 HydrophobicContact CG1-CG 4.31Å; I372-R385 HydrophobicContact CD1-CB 4.46Å
373	L	80.6	Confident	83.8	Confident	52 Å²	52	46.8 Å²	46.8	27%	0.272	27%	0.271	S	S	.	.	H	α-helix	trans	-65.2	-35.2	175.9	-179.4	67.7	0	0	0	112.8	Y247 L251 I254 N369 T370 T371	Y247-L373 HydrophobicContact CD1-CD1 3.26Å; Y247-L373 HydrophobicContact CD1-CG 4.46Å; Y247-L373 HydrophobicContact CE1-CD1 4.05Å; Y247-L373 HydrophobicContact CG-CD1 3.72Å; L251-L373 HydrophobicContact CD2-CD1 4.27Å; L251-L373 HydrophobicContact CD2-CD2 3.58Å; L251-L373 HydrophobicContact CG-CD1 4.22Å; L251-L373 HydrophobicContact CG-CD2 4.2Å; I254-L373 HydrophobicContact CD1-CD2 4.09Å; N369-L373 WeakPolarHBondContact O-CB 3.43Å; N369-L373 PolarHBondContact O-N 3.02Å; T370-L373 WeakPolarHBondContact O-CB 3.26Å; T370-L373 PolarHBondContact O-N 3.06Å; T371-L373 VanDerWaalsContact C-N 3.29Å; T371-L373 PolarHBondContact O-N 3.4Å
374	C	82.4	Confident	83.7	Confident	88 Å²	88	47.3 Å²	47.3	60%	0.595	27%	0.271	S	S	*	.	H	α-helix	trans	-85.8	-37.8	-177.3	-67.8	0	0	0	0	114.5	T370 T371 I372	T370-C374 PolarHBondContact O-N 3.46Å; T370-C374 PolarHBondContact O-SG 3.05Å; T371-C374 PolarHBondContact O-N 3.05Å; T371-C374 VanDerWaalsContact O-N 3.16Å; I372-C374 VanDerWaalsContact C-N 3.35Å; I372-C374 PolarHBondContact O-N 3.34Å
375	L	82.8	Confident	83.4	Confident	142 Å²	142	46 Å²	46	74%	0.743	26%	0.262	S	S	*	.	H	α-helix	trans	-110	-8.1	-171.6	-60.1	179.9	0	0	0	113.3	T371	T371-L375 HydrophobicContact CG2-CD1 3.73Å; T371-L375 HydrophobicContact CG2-CG 4.32Å; T371-L375 WeakPolarHBondContact O-CB 3.44Å; T371-L375 PolarHBondContact O-N 2.88Å
376	G	72.2	Confident	83.3	Confident	19 Å²	19	46 Å²	46	20%	0.196	26%	0.262	C	S	.	.			trans	84.5	166.2	-171.7	0	0	0	0	0	113.1	I372	I372-G376 CarbonylContact O-C 3.57Å; I372-G376 WeakPolarHBondContact O-CA 3.39Å; I372-G376 PolarHBondContact O-N 3.35Å
377	P	74.6	Confident	83.5	Confident	29 Å²	29	47.8 Å²	47.8	19%	0.188	27%	0.274	C	S	.	.			trans	-70.8	144.8	174.9	29.8	-34	0	0	0	111.6	L232 Y240	L232-P377 HydrophobicContact CD1-CB 4.17Å; Y240-P377 HydrophobicContact CD1-CB 4.34Å; Y240-P377 HydrophobicContact CD1-CG 3.54Å; Y240-P377 HydrophobicContact CE1-CB 3.88Å; Y240-P377 HydrophobicContact CE1-CG 3.58Å; Y240-P377 HydrophobicContact CG-CG 4.41Å
378	S	78.9	Confident	83.7	Confident	46 Å²	46	47 Å²	47	32%	0.322	27%	0.265	S	S	.	.			trans	-141.8	159.8	167.1	63.7	0	0	0	0	109.3	L380 L381 V382	S378-L380 PolarHBondContact O-N 2.87Å; S378-L381 PolarHBondContact O-N 3.04Å; S378-L381 WeakPolarHBondContact OG-CB 3.49Å; S378-L381 WeakPolarHBondContact OG-CD1 3.34Å; S378-L381 PolarHBondContact OG-N 2.86Å; S378-V382 WeakPolarHBondContact O-CG2 3.18Å; S378-V382 PolarHBondContact O-N 3.12Å
379	D	76.3	Confident	83.9	Confident	101 Å²	101	46.5 Å²	46.5	54%	0.54	26%	0.262	S	S	.	.	H	α-helix	trans	-54.5	-39.8	-178.3	-63.8	-19.8	0	0	0	113	K383	D379-K383 VanDerWaalsContact O-CG 3.31Å; D379-K383 WeakPolarHBondContact O-CG 3.13Å; D379-K383 PolarHBondContact O-N 3.38Å
380	L	83	Confident	84.3	Confident	113 Å²	113	46.9 Å²	46.9	59%	0.592	27%	0.265	S	S	*	.	H	α-helix	trans	-66.6	-44.5	176.2	179.3	61.8	0	0	0	111.3	S378 V382 K383 L384	S378-L380 PolarHBondContact O-N 2.87Å; L380-V382 VanDerWaalsContact C-N 3.32Å; L380-V382 PolarHBondContact O-N 3.22Å; L380-K383 PolarHBondContact O-N 3.26Å; L380-L384 HydrophobicContact CD1-CD1 4.14Å; L380-L384 HydrophobicContact CD1-CG 4.15Å; L380-L384 HydrophobicContact CG-CD1 3.95Å; L380-L384 HydrophobicContact CG-CG 4.39Å; L380-L384 WeakPolarHBondContact O-CB 3.33Å; L380-L384 VanDerWaalsContact O-CG 3.27Å; L380-L384 WeakPolarHBondContact O-CG 2.97Å; L380-L384 PolarHBondContact O-N 2.94Å
381	L	83.7	Confident	84.8	Confident	28 Å²	28	49.2 Å²	49.2	15%	0.147	27%	0.274	C	S	.	.	H	α-helix	trans	-65.1	-37.3	179.9	-90.6	63.6	0	0	0	111.2	L368 T371 I372 S378 R385	L368-L381 HydrophobicContact CD1-CG 4.1Å; T371-L381 HydrophobicContact CG2-CD2 4.04Å; I372-L381 HydrophobicContact CD1-CB 4.5Å; I372-L381 HydrophobicContact CG1-CB 4.05Å; I372-L381 HydrophobicContact CG1-CD2 3.79Å; I372-L381 HydrophobicContact CG1-CG 4.31Å; S378-L381 PolarHBondContact O-N 3.04Å; S378-L381 WeakPolarHBondContact OG-CB 3.49Å; S378-L381 WeakPolarHBondContact OG-CD1 3.34Å; S378-L381 PolarHBondContact OG-N 2.86Å; L381-R385 WeakPolarHBondContact O-CB 3.27Å; L381-R385 PolarHBondContact O-N 3.33Å
382	V	80.1	Confident	85.2	Confident	17 Å²	17	47 Å²	47	10%	0.103	26%	0.26	C	S	.	.	H	α-helix	trans	-67.5	-45.2	176.1	176.3	0	0	0	0	111.2	L233 S378 L380 L384 R385 L386	L233-V382 HydrophobicContact CD1-CG1 4.15Å; S378-V382 WeakPolarHBondContact O-CG2 3.18Å; S378-V382 PolarHBondContact O-N 3.12Å; L380-V382 VanDerWaalsContact C-N 3.32Å; L380-V382 PolarHBondContact O-N 3.22Å; V382-L384 PolarHBondContact O-N 3.47Å; V382-R385 WeakPolarHBondContact O-CB 3.48Å; V382-R385 PolarHBondContact O-N 3.09Å; V382-R385 VanDerWaalsContact O-N 3.17Å; V382-L386 PolarHBondContact O-N 2.73Å
383	K	84.1	Confident	85.8	Confident	82 Å²	82	47 Å²	47	36%	0.357	26%	0.26	S	S	.	.	H	α-helix	trans	-60.5	-45.2	174.8	-72.5	171.5	-175.6	173.8	0	111.9	Y73 F77 D379 L380 R385 L386 C387	Y73-K383 HydrophobicContact CD1-CG 4.24Å; Y73-K383 HydrophobicContact CE1-CG 4.13Å; F77-K383 HydrophobicContact CE2-CB 4.48Å; F77-K383 HydrophobicContact CZ-CB 4.28Å; D379-K383 VanDerWaalsContact O-CG 3.31Å; D379-K383 WeakPolarHBondContact O-CG 3.13Å; D379-K383 PolarHBondContact O-N 3.38Å; L380-K383 PolarHBondContact O-N 3.26Å; K383-R385 VanDerWaalsContact C-N 3.27Å; K383-R385 PolarHBondContact O-N 2.96Å; K383-L386 PolarHBondContact O-N 3.16Å; K383-C387 PolarHBondContact O-N 3.06Å; K383-C387 VanDerWaalsContact O-N 3.16Å; K383-C387 PolarHBondContact O-SG 2.92Å; K383-C387 VanDerWaalsContact O-SG 3.4Å
384	L	88.6	Confident	86.5	Confident	61 Å²	61	44.8 Å²	44.8	32%	0.319	25%	0.249	S	C	.	.	H	α-helix	trans	-63.2	-33.3	176.2	-73.5	174.8	0	0	0	112.4	L368 L380 V382 L386 C387 F388	L368-L384 HydrophobicContact CD1-CB 4.34Å; L368-L384 VanDerWaalsContact CD2-C 3.47Å; L368-L384 HydrophobicContact CD2-CB 3.81Å; L380-L384 HydrophobicContact CD1-CD1 4.14Å; L380-L384 HydrophobicContact CD1-CG 4.15Å; L380-L384 HydrophobicContact CG-CD1 3.95Å; L380-L384 HydrophobicContact CG-CG 4.39Å; L380-L384 WeakPolarHBondContact O-CB 3.33Å; L380-L384 VanDerWaalsContact O-CG 3.27Å; L380-L384 WeakPolarHBondContact O-CG 2.97Å; L380-L384 PolarHBondContact O-N 2.94Å; V382-L384 PolarHBondContact O-N 3.47Å; L384-L386 VanDerWaalsContact C-N 3.34Å; L384-C387 PolarHBondContact O-N 3.36Å; L384-F388 HydrophobicContact CB-CE2 4.39Å; L384-F388 WeakPolarHBondContact O-CD2 3.2Å; L384-F388 WeakPolarHBondContact O-CG 3.41Å; L384-F388 PolarHBondContact O-N 3.26Å
385	R	88.1	Confident	87	Confident	5 Å²	5	40.6 Å²	40.6	2%	0.019	22%	0.221	C	C	.	.	H	α-helix	trans	-62.7	-43.7	177.4	-173.8	-178.4	-179.3	-114.5	-0.6	111.1	E156 L368 N369 I372 L381 V382 K383 F388 L389	E156-R385 VanDerWaalsContact CD-NH2 3.34Å; E156-R385 IonicContact OE1-CZ 2.85Å; E156-R385 IonicContact OE1-NH1 3.46Å; E156-R385 PolarHBondContact OE1-NH1 3.44Å; E156-R385 IonicContact OE1-NH2 3.72Å; E156-R385 PolarHBondContact OE1-NH2 3.39Å; E156-R385 IonicContact OE2-CZ 3.99Å; E156-R385 IonicContact OE2-NH1 3.67Å; E156-R385 IonicContact OE2-NH2 2.74Å; E156-R385 PolarHBondContact OE2-NH2 2.79Å; L368-R385 HydrophobicContact CD2-CB 3.67Å; L368-R385 HydrophobicContact CD2-CG 4.44Å; N369-R385 PolarHBondContact OD1-NE 3.12Å; I372-R385 HydrophobicContact CD1-CB 4.46Å; L381-R385 WeakPolarHBondContact O-CB 3.27Å; L381-R385 PolarHBondContact O-N 3.33Å; V382-R385 WeakPolarHBondContact O-CB 3.48Å; V382-R385 PolarHBondContact O-N 3.09Å; V382-R385 VanDerWaalsContact O-N 3.17Å; K383-R385 VanDerWaalsContact C-N 3.27Å; K383-R385 PolarHBondContact O-N 2.96Å; R385-F388 PolarHBondContact O-N 3.24Å; R385-L389 VanDerWaalsContact O-CB 3.26Å; R385-L389 WeakPolarHBondContact O-CB 3.28Å; R385-L389 PolarHBondContact O-N 2.91Å
386	L	88.2	Confident	87.5	Confident	2 Å²	2	33.9 Å²	33.9	1%	0.01	19%	0.186	C	C	.	.	H	α-helix	trans	-63.5	-43.9	174.7	-68.4	169.6	0	0	0	111.6	Y73 F77 L81 L140 L233 V382 K383 L384 F388 L389 V390	Y73-L386 HydrophobicContact CE1-CD1 3.81Å; Y73-L386 HydrophobicContact CE2-CD1 4.21Å; Y73-L386 WeakPolarHBondContact OH-CD1 3.46Å; F77-L386 HydrophobicContact CE1-CD1 4.28Å; F77-L386 HydrophobicContact CZ-CB 4.36Å; L81-L386 HydrophobicContact CD2-CB 3.85Å; L140-L386 HydrophobicContact CD2-CD1 3.84Å; L140-L386 HydrophobicContact CD2-CD2 4.29Å; L233-L386 HydrophobicContact CD1-CD2 4.23Å; V382-L386 PolarHBondContact O-N 2.73Å; K383-L386 PolarHBondContact O-N 3.16Å; L384-L386 VanDerWaalsContact C-N 3.34Å; L386-F388 PolarHBondContact O-N 2.81Å; L386-L389 WeakPolarHBondContact O-CB 3.28Å; L386-L389 PolarHBondContact O-N 2.98Å; L386-V390 VanDerWaalsContact O-CG2 3.32Å; L386-V390 WeakPolarHBondContact O-CG2 3.47Å; L386-V390 PolarHBondContact O-N 3.33Å
387	C	92.5	Very high	88.5	Confident	44 Å²	44	34 Å²	34	30%	0.297	18%	0.182	S	C	.	.	H	α-helix	trans	-59.7	-46.3	176	-63.9	0	0	0	0	112.8	F77 K383 L384 L389 V390 M391	F77-C387 VanDerWaalsContact CE2-SG 3.55Å; K383-C387 PolarHBondContact O-N 3.06Å; K383-C387 VanDerWaalsContact O-N 3.16Å; K383-C387 PolarHBondContact O-SG 2.92Å; K383-C387 VanDerWaalsContact O-SG 3.4Å; L384-C387 PolarHBondContact O-N 3.36Å; C387-L389 VanDerWaalsContact C-N 3.31Å; C387-V390 PolarHBondContact O-N 3.29Å; C387-M391 PolarHBondContact O-N 3.06Å; C387-M391 VanDerWaalsContact O-N 3.09Å
388	F	94.4	Very high	89.1	Confident	55 Å²	55	37.1 Å²	37.1	24%	0.241	19%	0.193	C	C	.	.	H	α-helix	trans	-72.6	-25.8	178.5	-63.6	-29.9	0	0	0	112.8	P364 I365 L368 L384 R385 L386 M391 A392	P364-F388 HydrophobicContact CB-CB 4.12Å; P364-F388 HydrophobicContact CB-CD1 3.64Å; P364-F388 HydrophobicContact CB-CD2 3.9Å; P364-F388 HydrophobicContact CB-CE1 3.96Å; P364-F388 HydrophobicContact CB-CE2 4.21Å; P364-F388 HydrophobicContact CB-CG 3.62Å; P364-F388 HydrophobicContact CB-CZ 4.25Å; I365-F388 HydrophobicContact CB-CB 3.86Å; L368-F388 HydrophobicContact CB-CD2 3.97Å; L368-F388 HydrophobicContact CB-CE2 4.24Å; L368-F388 HydrophobicContact CD1-CE2 4.46Å; L368-F388 HydrophobicContact CD2-CD2 3.67Å; L368-F388 HydrophobicContact CD2-CE2 4.08Å; L368-F388 HydrophobicContact CG-CD2 4.36Å; L384-F388 HydrophobicContact CB-CE2 4.39Å; L384-F388 WeakPolarHBondContact O-CD2 3.2Å; L384-F388 WeakPolarHBondContact O-CG 3.41Å; L384-F388 PolarHBondContact O-N 3.26Å; R385-F388 PolarHBondContact O-N 3.24Å; L386-F388 PolarHBondContact O-N 2.81Å; F388-M391 HydrophobicContact CD1-CE 4.45Å; F388-M391 PolarHBondContact O-N 3.18Å; F388-A392 WeakPolarHBondContact O-CB 3.43Å; F388-A392 PolarHBondContact O-N 2.78Å
389	L	92.7	Very high	89.5	Confident	3 Å²	3	34.9 Å²	34.9	2%	0.016	18%	0.177	C	C	.	.	H	α-helix	trans	-66	-44.8	171.8	-178	60.6	0	0	0	111.4	T136 V159 I365 R385 L386 C387 M391 A392 Y393	T136-L389 HydrophobicContact CG2-CD2 4.15Å; V159-L389 HydrophobicContact CG1-CD1 3.95Å; V159-L389 HydrophobicContact CG2-CD1 4.02Å; V159-L389 HydrophobicContact CG2-CD2 3.84Å; I365-L389 HydrophobicContact CD1-CB 3.82Å; I365-L389 HydrophobicContact CD1-CD1 3.77Å; I365-L389 HydrophobicContact CD1-CG 4.39Å; R385-L389 VanDerWaalsContact O-CB 3.26Å; R385-L389 WeakPolarHBondContact O-CB 3.28Å; R385-L389 PolarHBondContact O-N 2.91Å; L386-L389 WeakPolarHBondContact O-CB 3.28Å; L386-L389 PolarHBondContact O-N 2.98Å; C387-L389 VanDerWaalsContact C-N 3.31Å; L389-M391 VanDerWaalsContact C-N 3.31Å; L389-M391 PolarHBondContact O-N 2.89Å; L389-A392 WeakPolarHBondContact O-CB 3.42Å; L389-A392 PolarHBondContact O-N 3.36Å; L389-A392 VanDerWaalsContact O-N 3.08Å; L389-Y393 HydrophobicContact CD1-CE1 4.1Å; L389-Y393 HydrophobicContact CD1-CE2 4.01Å; L389-Y393 HydrophobicContact CD2-CE2 4.13Å; L389-Y393 HydrophobicContact CG-CD2 4.29Å; L389-Y393 HydrophobicContact CG-CE2 3.68Å; L389-Y393 PolarHBondContact O-N 2.98Å
390	V	94.8	Very high	89.7	Confident	10 Å²	10	30.4 Å²	30.4	6%	0.061	15%	0.154	C	C	.	.	H	α-helix	trans	-59	-46.1	172.8	179.5	0	0	0	0	110.3	L81 F84 L85 L386 C387 A392 Y393 G394	L81-V390 HydrophobicContact CD1-CB 4.11Å; L81-V390 HydrophobicContact CD1-CG1 4.44Å; L81-V390 HydrophobicContact CD1-CG2 3.47Å; L81-V390 VanDerWaalsContact CD1-CG2 3.47Å; L81-V390 HydrophobicContact CD2-CG2 3.97Å; L81-V390 HydrophobicContact CG-CG2 3.54Å; F84-V390 HydrophobicContact CB-CG1 4.04Å; L85-V390 HydrophobicContact CD1-CG2 4.09Å; L85-V390 HydrophobicContact CD2-CB 4.25Å; L85-V390 HydrophobicContact CD2-CG1 4.04Å; L85-V390 HydrophobicContact CD2-CG2 3.7Å; L85-V390 HydrophobicContact CG-CG1 4.28Å; L85-V390 HydrophobicContact CG-CG2 3.88Å; L386-V390 VanDerWaalsContact O-CG2 3.32Å; L386-V390 WeakPolarHBondContact O-CG2 3.47Å; L386-V390 PolarHBondContact O-N 3.33Å; C387-V390 PolarHBondContact O-N 3.29Å; V390-A392 PolarHBondContact O-N 3.36Å; V390-Y393 PolarHBondContact O-N 3.32Å; V390-Y393 VanDerWaalsContact O-N 3.1Å; V390-G394 PolarHBondContact O-N 3.43Å
391	M	95.3	Very high	89.3	Confident	89 Å²	89	28.2 Å²	28.2	44%	0.438	14%	0.142	S	C	.	.	H	α-helix	trans	-57.4	-36.1	174.8	-170.6	180	-64.2	0	0	113.3	C361 P364 C387 F388 L389 G394	C361-M391 WeakPolarHBondContact CB-O 3.34Å; C361-M391 PolarHBondContact SG-O 3.15Å; C361-M391 VanDerWaalsContact SG-O 3.37Å; P364-M391 HydrophobicContact CG-SD 4.05Å; C387-M391 PolarHBondContact O-N 3.06Å; C387-M391 VanDerWaalsContact O-N 3.09Å; F388-M391 HydrophobicContact CD1-CE 4.45Å; F388-M391 PolarHBondContact O-N 3.18Å; L389-M391 VanDerWaalsContact C-N 3.31Å; L389-M391 PolarHBondContact O-N 2.89Å; M391-G394 PolarHBondContact O-N 2.91Å
392	A	94.4	Very high	88.7	Confident	0 Å²	0	28.2 Å²	28.2	0%	0	14%	0.142	C	C	.	.	H	α-helix	trans	-66.6	-43.5	175.9	0	0	0	0	0	112	W362 I365 F388 L389 V390 G394 T395	W362-A392 HydrophobicContact CD2-CB 3.85Å; W362-A392 HydrophobicContact CE3-CB 3.83Å; W362-A392 HydrophobicContact CG-CB 4.43Å; W362-A392 HydrophobicContact CH2-CB 4.09Å; W362-A392 HydrophobicContact CZ2-CB 4.14Å; W362-A392 HydrophobicContact CZ3-CB 3.92Å; I365-A392 HydrophobicContact CG2-CB 4.21Å; F388-A392 WeakPolarHBondContact O-CB 3.43Å; F388-A392 PolarHBondContact O-N 2.78Å; L389-A392 WeakPolarHBondContact O-CB 3.42Å; L389-A392 PolarHBondContact O-N 3.36Å; L389-A392 VanDerWaalsContact O-N 3.08Å; V390-A392 PolarHBondContact O-N 3.36Å; A392-G394 VanDerWaalsContact C-N 3.26Å; A392-G394 PolarHBondContact O-N 2.98Å; A392-T395 WeakPolarHBondContact O-CB 3.49Å; A392-T395 WeakPolarHBondContact O-CG2 3.15Å; A392-T395 PolarHBondContact O-N 3.45Å; A392-T395 PolarHBondContact O-OG1 3.02Å
393	Y	95.4	Very high	88.2	Confident	1 Å²	1	29 Å²	29	0%	0.004	14%	0.143	C	C	.	.	H	α-helix	trans	-64.8	-27.7	175.5	-66.6	-34.7	0	0	0	113.5	L85 E88 I128 C132 I133 T136 A162 L389 V390 T395 T396	L85-Y393 HydrophobicContact CD2-CD2 3.84Å; L85-Y393 HydrophobicContact CD2-CE2 4.43Å; E88-Y393 WeakPolarHBondContact OE2-CB 3.47Å; I128-Y393 HydrophobicContact CG2-CD1 3.73Å; I128-Y393 HydrophobicContact CG2-CE1 4.1Å; C132-Y393 HydrophobicContact CB-CE1 3.95Å; I133-Y393 HydrophobicContact CD1-CG 4.4Å; I133-Y393 HydrophobicContact CG1-CD1 4.41Å; I133-Y393 HydrophobicContact CG1-CD2 3.94Å; I133-Y393 HydrophobicContact CG1-CE2 4.4Å; I133-Y393 HydrophobicContact CG1-CG 3.94Å; T136-Y393 HydrophobicContact CG2-CE2 4.24Å; T136-Y393 VanDerWaalsContact OG1-CE2 3.3Å; T136-Y393 WeakPolarHBondContact OG1-CE2 3.44Å; T136-Y393 PolarHBondContact OG1-OH 3.46Å; A162-Y393 HydrophobicContact CB-CE1 4.19Å; L389-Y393 HydrophobicContact CD1-CE1 4.1Å; L389-Y393 HydrophobicContact CD1-CE2 4.01Å; L389-Y393 HydrophobicContact CD2-CE2 4.13Å; L389-Y393 HydrophobicContact CG-CD2 4.29Å; L389-Y393 HydrophobicContact CG-CE2 3.68Å; L389-Y393 PolarHBondContact O-N 2.98Å; V390-Y393 PolarHBondContact O-N 3.32Å; V390-Y393 VanDerWaalsContact O-N 3.1Å; Y393-T395 PolarHBondContact O-N 3.36Å; Y393-T396 WeakPolarHBondContact O-CB 3.37Å; Y393-T396 WeakPolarHBondContact O-CG2 3.09Å; Y393-T396 PolarHBondContact O-N 3.41Å; Y393-T396 PolarHBondContact O-OG1 3.14Å
394	G	93.8	Very high	87.3	Confident	5 Å²	5	27.3 Å²	27.3	5%	0.052	15%	0.145	C	C	.	.	T	Hydrogen-bonded Turn	trans	-52.9	-20.3	171.4	0	0	0	0	0	114.9	E88 V390 M391 A392 T396 I397 F398	E88-G394 PolarHBondContact OE1-N 3.48Å; V390-G394 PolarHBondContact O-N 3.43Å; M391-G394 PolarHBondContact O-N 2.91Å; A392-G394 VanDerWaalsContact C-N 3.26Å; A392-G394 PolarHBondContact O-N 2.98Å; G394-T396 PolarHBondContact O-N 2.93Å; G394-I397 PolarHBondContact O-N 3.05Å; G394-I397 VanDerWaalsContact O-N 3.13Å; G394-F398 WeakPolarHBondContact O-CD2 3.36Å; G394-F398 PolarHBondContact O-N 3.39Å
395	T	92.6	Very high	85.9	Confident	1 Å²	1	29.9 Å²	29.9	1%	0.006	15%	0.154	C	C	.	.	H	α-helix	trans	-53.6	-34.4	171.1	51.9	0	0	0	0	113.3	T357 C361 A392 Y393 I397 F398 H399	T357-T395 HydrophobicContact CG2-CG2 4.4Å; C361-T395 HydrophobicContact CB-CG2 3.36Å; A392-T395 WeakPolarHBondContact O-CB 3.49Å; A392-T395 WeakPolarHBondContact O-CG2 3.15Å; A392-T395 PolarHBondContact O-N 3.45Å; A392-T395 PolarHBondContact O-OG1 3.02Å; Y393-T395 PolarHBondContact O-N 3.36Å; T395-I397 VanDerWaalsContact C-N 3.29Å; T395-I397 PolarHBondContact O-N 3.02Å; T395-F398 PolarHBondContact O-N 3.06Å; T395-H399 PolarHBondContact O-N 3.1Å; T395-H399 VanDerWaalsContact O-N 3.1Å; T395-H399 PolarHBondContact O-ND1 2.97Å
396	T	93.4	Very high	84.6	Confident	0 Å²	0	30 Å²	30	0%	0	16%	0.155	C	C	.	.	H	α-helix	trans	-60.9	-34.6	179.1	61.7	0	0	0	0	112.6	N96 D125 I128 Y393 G394 P400	N96-T396 PolarHBondContact ND2-O 3.5Å; D125-T396 HydrophobicContact CB-CG2 4.13Å; I128-T396 HydrophobicContact CB-CG2 4.06Å; I128-T396 HydrophobicContact CG2-CG2 3.8Å; Y393-T396 WeakPolarHBondContact O-CB 3.37Å; Y393-T396 WeakPolarHBondContact O-CG2 3.09Å; Y393-T396 PolarHBondContact O-N 3.41Å; Y393-T396 PolarHBondContact O-OG1 3.14Å; G394-T396 PolarHBondContact O-N 2.93Å; T396-P400 WeakPolarHBondContact O-CD 3.5Å
397	I	92.9	Very high	83.2	Confident	22 Å²	22	37.1 Å²	37.1	11%	0.113	18%	0.182	C	C	.	.	H	α-helix	trans	-76.4	-45.2	175.8	-56.7	165.5	0	0	0	110.2	E88 L91 G394 T395 H399 L401	E88-I397 HydrophobicContact CB-CD1 4.24Å; E88-I397 HydrophobicContact CG-CD1 3.66Å; E88-I397 HydrophobicContact CG-CG1 4.44Å; L91-I397 HydrophobicContact CB-CD1 4.16Å; L91-I397 HydrophobicContact CB-CG1 3.94Å; L91-I397 HydrophobicContact CB-CG2 4.07Å; L91-I397 HydrophobicContact CD1-CD1 4.24Å; L91-I397 HydrophobicContact CD1-CG2 4.42Å; G394-I397 PolarHBondContact O-N 3.05Å; G394-I397 VanDerWaalsContact O-N 3.13Å; T395-I397 VanDerWaalsContact C-N 3.29Å; T395-I397 PolarHBondContact O-N 3.02Å; I397-H399 VanDerWaalsContact C-N 3.33Å; I397-H399 PolarHBondContact O-N 3.04Å; I397-L401 HydrophobicContact CG2-CD1 3.67Å; I397-L401 HydrophobicContact CG2-CG 4.33Å; I397-L401 WeakPolarHBondContact O-CG 3.5Å
398	F	88.8	Confident	81.4	Confident	94 Å²	94	37 Å²	37	41%	0.412	18%	0.177	S	C	.	.	H	α-helix	trans	-66.6	-35.3	-170.4	-69.5	-55.4	0	0	0	112.4	T357 G394 T395 L401 L402	T357-F398 HydrophobicContact CG2-CB 3.54Å; T357-F398 HydrophobicContact CG2-CD2 3.59Å; T357-F398 HydrophobicContact CG2-CG 3.8Å; G394-F398 WeakPolarHBondContact O-CD2 3.36Å; G394-F398 PolarHBondContact O-N 3.39Å; T395-F398 PolarHBondContact O-N 3.06Å; F398-L401 PolarHBondContact O-N 3.33Å; F398-L402 WeakPolarHBondContact O-CB 3.44Å; F398-L402 WeakPolarHBondContact O-CG 3.37Å; F398-L402 PolarHBondContact O-N 2.75Å
399	H	86	Confident	79.3	Confident	0 Å²	0	42.3 Å²	42.3	0%	0	20%	0.2	C	C	.	.	H	α-helix	trans	-51.7	-69.8	-179.8	-68.5	150.8	0	0	0	111.3	L121 D125 T395 I397 L401 L402 Y403	L121-H399 HydrophobicContact CD2-CB 4.16Å; D125-H399 IonicContact OD1-CE1 3Å; D125-H399 IonicContact OD1-ND1 3.76Å; D125-H399 PolarHBondContact OD1-ND1 3.04Å; D125-H399 WeakPolarHBondContact OD2-CB 3.43Å; D125-H399 IonicContact OD2-CE1 3.54Å; D125-H399 IonicContact OD2-CG 3.86Å; D125-H399 IonicContact OD2-ND1 4Å; D125-H399 PolarHBondContact OD2-ND1 3.44Å; T395-H399 PolarHBondContact O-N 3.1Å; T395-H399 VanDerWaalsContact O-N 3.1Å; T395-H399 PolarHBondContact O-ND1 2.97Å; I397-H399 VanDerWaalsContact C-N 3.33Å; I397-H399 PolarHBondContact O-N 3.04Å; H399-L401 VanDerWaalsContact C-N 3.29Å; H399-L401 PolarHBondContact O-N 3.46Å; H399-L401 VanDerWaalsContact O-N 3.17Å; H399-L402 WeakPolarHBondContact O-CB 3.44Å; H399-L402 PolarHBondContact O-N 3.35Å; H399-Y403 WeakPolarHBondContact O-CD2 3.34Å; H399-Y403 PolarHBondContact O-N 3.17Å; H399-Y403 VanDerWaalsContact O-N 3.17Å
400	P	82.1	Confident	77	Confident	7 Å²	7	47.2 Å²	47.2	5%	0.045	22%	0.222	C	C	.	.	H	α-helix	trans	-50.6	-40.9	177.2	-30.5	36	0	0	0	115.6	S95 N96 V99 T396 L402 Y403 A404	S95-P400 WeakPolarHBondContact OG-CG 3.22Å; N96-P400 HydrophobicContact CB-CG 4.28Å; N96-P400 WeakPolarHBondContact OD1-CD 3.39Å; N96-P400 WeakPolarHBondContact OD1-CG 3.28Å; V99-P400 HydrophobicContact CG2-CB 4.21Å; T396-P400 WeakPolarHBondContact O-CD 3.5Å; P400-L402 VanDerWaalsContact C-N 3.33Å; P400-L402 PolarHBondContact O-N 2.99Å; P400-Y403 CarbonylContact O-C 3.21Å; P400-Y403 WeakPolarHBondContact O-CA 3.47Å; P400-Y403 WeakPolarHBondContact O-CB 3.46Å; P400-Y403 PolarHBondContact O-N 3.15Å; P400-Y403 VanDerWaalsContact O-N 3.09Å; P400-A404 PolarHBondContact O-N 3.27Å
401	L	72.6	Confident	75.1	Confident	67 Å²	67	50.5 Å²	50.5	35%	0.351	24%	0.236	S	C	.	.	H	α-helix	trans	-62.6	-41.6	179.4	-69.3	-177.1	0	0	0	111.2	I397 F398 H399 Y403 A404 F405	I397-L401 HydrophobicContact CG2-CD1 3.67Å; I397-L401 HydrophobicContact CG2-CG 4.33Å; I397-L401 WeakPolarHBondContact O-CG 3.5Å; F398-L401 PolarHBondContact O-N 3.33Å; H399-L401 VanDerWaalsContact C-N 3.29Å; H399-L401 PolarHBondContact O-N 3.46Å; H399-L401 VanDerWaalsContact O-N 3.17Å; L401-Y403 VanDerWaalsContact C-N 3.31Å; L401-Y403 PolarHBondContact O-N 3.08Å; L401-A404 PolarHBondContact O-N 3.46Å; L401-F405 HydrophobicContact CB-CD2 4.04Å; L401-F405 HydrophobicContact CB-CE2 3.95Å; L401-F405 HydrophobicContact CD2-CE2 3.97Å; L401-F405 HydrophobicContact CG-CE2 4.4Å; L401-F405 WeakPolarHBondContact O-CB 3.28Å; L401-F405 WeakPolarHBondContact O-CD2 3.46Å; L401-F405 WeakPolarHBondContact O-CG 3.5Å; L401-F405 PolarHBondContact O-N 3.44Å
402	L	73	Confident	73.3	Confident	27 Å²	27	53.2 Å²	53.2	14%	0.141	25%	0.246	C	C	.	.	H	α-helix	trans	-63.9	-35.6	174	-66.2	173.5	0	0	0	111.5	L353 I354 F398 H399 P400 T406	L353-L402 HydrophobicContact CB-CD1 4Å; L353-L402 HydrophobicContact CB-CD2 3.9Å; L353-L402 HydrophobicContact CB-CG 4.43Å; L353-L402 HydrophobicContact CD1-CD2 4.12Å; L353-L402 HydrophobicContact CG-CD2 4.41Å; I354-L402 HydrophobicContact CG1-CD1 4.43Å; F398-L402 WeakPolarHBondContact O-CB 3.44Å; F398-L402 WeakPolarHBondContact O-CG 3.37Å; F398-L402 PolarHBondContact O-N 2.75Å; H399-L402 WeakPolarHBondContact O-CB 3.44Å; H399-L402 PolarHBondContact O-N 3.35Å; P400-L402 VanDerWaalsContact C-N 3.33Å; P400-L402 PolarHBondContact O-N 2.99Å; L402-T406 VanDerWaalsContact O-CB 3.23Å; L402-T406 WeakPolarHBondContact O-CB 3.35Å; L402-T406 WeakPolarHBondContact O-CG2 3.28Å; L402-T406 PolarHBondContact O-N 2.75Å; L402-T406 VanDerWaalsContact O-N 3.15Å; L402-T406 PolarHBondContact O-OG1 2.74Å
403	Y	68.3	Low	71.3	Confident	33 Å²	33	56.9 Å²	56.9	13%	0.129	27%	0.268	C	S	.	.	H	α-helix	trans	-65.7	-38.5	171.9	-74	-103.6	0	0	0	112.8	T118 M350 I354 H399 P400 L401	T118-Y403 HydrophobicContact CG2-CD1 3.96Å; T118-Y403 HydrophobicContact CG2-CE1 3.16Å; T118-Y403 HydrophobicContact CG2-CE2 4.37Å; T118-Y403 VanDerWaalsContact CG2-CZ 3.43Å; T118-Y403 WeakPolarHBondContact CG2-OH 3Å; T118-Y403 PolarHBondContact OG1-OH 3.2Å; M350-Y403 HydrophobicContact CE-CD1 2.84Å; M350-Y403 HydrophobicContact CE-CD2 3.53Å; M350-Y403 HydrophobicContact CE-CE1 3.06Å; M350-Y403 HydrophobicContact CE-CE2 3.78Å; M350-Y403 HydrophobicContact CE-CG 3.01Å; M350-Y403 HydrophobicContact SD-CD1 4.29Å; M350-Y403 HydrophobicContact SD-CE1 4.29Å; I354-Y403 HydrophobicContact CD1-CE2 3.55Å; I354-Y403 WeakPolarHBondContact CD1-OH 3.45Å; I354-Y403 HydrophobicContact CG1-CE2 4.29Å; H399-Y403 WeakPolarHBondContact O-CD2 3.34Å; H399-Y403 PolarHBondContact O-N 3.17Å; H399-Y403 VanDerWaalsContact O-N 3.17Å; P400-Y403 CarbonylContact O-C 3.21Å; P400-Y403 WeakPolarHBondContact O-CA 3.47Å; P400-Y403 WeakPolarHBondContact O-CB 3.46Å; P400-Y403 PolarHBondContact O-N 3.15Å; P400-Y403 VanDerWaalsContact O-N 3.09Å; L401-Y403 VanDerWaalsContact C-N 3.31Å; L401-Y403 PolarHBondContact O-N 3.08Å
404	A	65.3	Low	69.2	Low	48 Å²	48	60.9 Å²	60.9	40%	0.397	29%	0.289	S	S	.	.	H	α-helix	trans	-71.8	-50.7	178.3	0	0	0	0	0	112.3	P400 L401 T406 R407	P400-A404 PolarHBondContact O-N 3.27Å; L401-A404 PolarHBondContact O-N 3.46Å; A404-T406 PolarHBondContact O-N 3.13Å; A404-R407 PolarHBondContact O-N 3.1Å
405	F	59.2	Low	67.5	Low	114 Å²	114	67.5 Å²	67.5	50%	0.5	32%	0.316	S	S	.	.	H	α-helix	trans	-73.1	-27.1	-174.5	-70	-59.5	0	0	0	113.6	L401 R407 F410 Q411	L401-F405 HydrophobicContact CB-CD2 4.04Å; L401-F405 HydrophobicContact CB-CE2 3.95Å; L401-F405 HydrophobicContact CD2-CE2 3.97Å; L401-F405 HydrophobicContact CG-CE2 4.4Å; L401-F405 WeakPolarHBondContact O-CB 3.28Å; L401-F405 WeakPolarHBondContact O-CD2 3.46Å; L401-F405 WeakPolarHBondContact O-CG 3.5Å; L401-F405 PolarHBondContact O-N 3.44Å; F405-R407 VanDerWaalsContact C-N 3.32Å; F405-R407 PolarHBondContact O-N 2.54Å; F405-F410 HydrophobicContact CE1-CE1 4.47Å; F405-Q411 PolarHBondContact O-NE2 2.82Å
406	T	60.4	Low	65.7	Low	7 Å²	7	70.1 Å²	70.1	4%	0.043	34%	0.335	C	S	.	.	T	Hydrogen-bonded Turn	trans	-78.7	-13.6	177.5	59.7	0	0	0	0	113.5	R346 M350 L353 L402 A404 Q408	R346-T406 WeakPolarHBondContact CD-O 3.26Å; R346-T406 WeakPolarHBondContact CG-O 3.35Å; M350-T406 HydrophobicContact CB-CG2 4.2Å; M350-T406 HydrophobicContact CG-CG2 4.33Å; L353-T406 HydrophobicContact CD1-CG2 3.52Å; L402-T406 VanDerWaalsContact O-CB 3.23Å; L402-T406 WeakPolarHBondContact O-CB 3.35Å; L402-T406 WeakPolarHBondContact O-CG2 3.28Å; L402-T406 PolarHBondContact O-N 2.75Å; L402-T406 VanDerWaalsContact O-N 3.15Å; L402-T406 PolarHBondContact O-OG1 2.74Å; A404-T406 PolarHBondContact O-N 3.13Å; T406-Q408 PolarHBondContact O-N 3.04Å; T406-Q408 VanDerWaalsContact O-N 3.14Å
407	R	59.6	Low	63.9	Low	153 Å²	153	76.8 Å²	76.8	58%	0.577	36%	0.363	S	S	*	.			trans	-70.8	108.9	174.4	-86	-175.4	171.6	-159	2.8	110.4	A404 F405 K409 F410 Q411	A404-R407 PolarHBondContact O-N 3.1Å; F405-R407 VanDerWaalsContact C-N 3.32Å; F405-R407 PolarHBondContact O-N 2.54Å; R407-K409 PolarHBondContact O-N 2.9Å; R407-F410 PolarHBondContact O-N 3.42Å; R407-Q411 PolarHBondContact O-N 3.27Å
408	Q	53.6	Low	62	Low	42 Å²	42	81.2 Å²	81.2	20%	0.196	39%	0.385	C	S	.	.	H	α-helix	trans	-52.6	-21.1	173.6	-65.6	175.5	-7.9	0	0	114.3	T406 K412	T406-Q408 PolarHBondContact O-N 3.04Å; T406-Q408 VanDerWaalsContact O-N 3.14Å; Q408-K412 WeakPolarHBondContact O-CB 3.45Å; Q408-K412 WeakPolarHBondContact O-CG 3.33Å; Q408-K412 PolarHBondContact O-N 2.89Å
409	K	50.7	Low	60.6	Low	166 Å²	166	84.2 Å²	84.2	72%	0.722	40%	0.398	S	S	*	.	H	α-helix	trans	-68.5	-42.1	174.7	-73.8	-169.1	176.9	-172.9	0	111.4	R407 K412 V413	R407-K409 PolarHBondContact O-N 2.9Å; K409-K412 PolarHBondContact O-N 3.39Å; K409-V413 WeakPolarHBondContact O-CG2 3.32Å; K409-V413 PolarHBondContact O-N 3.49Å
410	F	44.7	Very low	59.1	Low	106 Å²	106	91.8 Å²	91.8	47%	0.465	43%	0.431	S	S	.	.	H	α-helix	trans	-68.2	-43.5	177.1	-166	-102.2	0	0	0	110.7	F405 R407 K412 V413 L414	F405-F410 HydrophobicContact CE1-CE1 4.47Å; R407-F410 PolarHBondContact O-N 3.42Å; F410-K412 VanDerWaalsContact C-N 3.29Å; F410-K412 PolarHBondContact O-N 3.4Å; F410-V413 PolarHBondContact O-N 2.93Å; F410-V413 VanDerWaalsContact O-N 3.14Å; F410-L414 VanDerWaalsContact O-CB 3.31Å; F410-L414 WeakPolarHBondContact O-CB 3.37Å; F410-L414 PolarHBondContact O-N 3.39Å
411	Q	54.4	Low	57.8	Low	79 Å²	79	100.5 Å²	100.5	37%	0.369	46%	0.463	S	S	.	.	H	α-helix	trans	-60.8	-35.5	172.5	-66.5	-169.8	-3.3	0	0	113.1	F405 R407 K415	F405-Q411 PolarHBondContact O-NE2 2.82Å; R407-Q411 PolarHBondContact O-N 3.27Å; Q411-K415 WeakPolarHBondContact O-CB 3.25Å; Q411-K415 WeakPolarHBondContact O-CG 3.41Å; Q411-K415 PolarHBondContact O-N 3.43Å
412	K	57.6	Low	56.9	Low	146 Å²	146	101.5 Å²	101.5	64%	0.635	47%	0.472	S	S	*	.	H	α-helix	trans	-69.7	-36.5	175.2	-78.5	176	-176.7	-171.2	0	112.4	Q408 K409 F410 S416	Q408-K412 WeakPolarHBondContact O-CB 3.45Å; Q408-K412 WeakPolarHBondContact O-CG 3.33Å; Q408-K412 PolarHBondContact O-N 2.89Å; K409-K412 PolarHBondContact O-N 3.39Å; F410-K412 VanDerWaalsContact C-N 3.29Å; F410-K412 PolarHBondContact O-N 3.4Å; K412-S416 WeakPolarHBondContact O-CB 3Å; K412-S416 PolarHBondContact O-N 3.36Å; K412-S416 PolarHBondContact O-OG 2.87Å
413	V	53.5	Low	56	Low	76 Å²	76	103.6 Å²	103.6	46%	0.461	49%	0.485	S	S	.	.	H	α-helix	trans	-72.5	-41.3	175.6	173	0	0	0	0	111	K409 F410 S416 K417	K409-V413 WeakPolarHBondContact O-CG2 3.32Å; K409-V413 PolarHBondContact O-N 3.49Å; F410-V413 PolarHBondContact O-N 2.93Å; F410-V413 VanDerWaalsContact O-N 3.14Å; V413-S416 WeakPolarHBondContact CA-OG 3.31Å; V413-S416 PolarHBondContact O-N 3.29Å; V413-S416 PolarHBondContact O-OG 3.15Å; V413-K417 WeakPolarHBondContact O-CB 3.01Å; V413-K417 WeakPolarHBondContact O-CG 3.48Å; V413-K417 PolarHBondContact O-N 3.09Å
414	L	51.6	Low	55.1	Low	86 Å²	86	105.9 Å²	105.9	45%	0.45	51%	0.506	S	S	.	.	H	α-helix	trans	-66.9	-46.7	175.6	-167.2	71.7	0	0	0	110.6	F410 S416 K417 M418	F410-L414 VanDerWaalsContact O-CB 3.31Å; F410-L414 WeakPolarHBondContact O-CB 3.37Å; F410-L414 PolarHBondContact O-N 3.39Å; L414-S416 VanDerWaalsContact C-N 3.35Å; L414-S416 PolarHBondContact O-N 2.03Å; L414-K417 PolarHBondContact O-N 2.9Å; L414-M418 HydrophobicContact CG-SD 4.38Å; L414-M418 WeakPolarHBondContact O-CB 3.17Å; L414-M418 VanDerWaalsContact O-CG 3.28Å; L414-M418 WeakPolarHBondContact O-CG 3.49Å; L414-M418 PolarHBondContact O-N 3.44Å
415	K	56.9	Low	54.3	Low	144 Å²	144	109.4 Å²	109.4	63%	0.626	52%	0.517	S	S	*	.	H	α-helix	trans	-65.8	-33.2	173.9	-72.3	-178.2	179.4	-167.1	0	112.6	Q411 K419	Q411-K415 WeakPolarHBondContact O-CB 3.25Å; Q411-K415 WeakPolarHBondContact O-CG 3.41Å; Q411-K415 PolarHBondContact O-N 3.43Å; K415-K419 WeakPolarHBondContact O-CB 3.49Å; K415-K419 PolarHBondContact O-N 3.23Å
416	S	56	Low	53.9	Low	56 Å²	56	109.3 Å²	109.3	39%	0.392	53%	0.526	S	S	.	.	H	α-helix	trans	-73.2	-36.4	174.9	72.9	0	0	0	0	112	K412 V413 L414 K420	K412-S416 WeakPolarHBondContact O-CB 3Å; K412-S416 PolarHBondContact O-N 3.36Å; K412-S416 PolarHBondContact O-OG 2.87Å; V413-S416 WeakPolarHBondContact CA-OG 3.31Å; V413-S416 PolarHBondContact O-N 3.29Å; V413-S416 PolarHBondContact O-OG 3.15Å; L414-S416 VanDerWaalsContact C-N 3.35Å; L414-S416 PolarHBondContact O-N 2.03Å; S416-K420 WeakPolarHBondContact O-CB 3.41Å; S416-K420 VanDerWaalsContact O-CG 3.25Å; S416-K420 WeakPolarHBondContact O-CG 3.39Å; S416-K420 PolarHBondContact O-N 3.01Å
417	K	54.8	Low	53.3	Low	140 Å²	140	116.5 Å²	116.5	61%	0.609	56%	0.559	S	S	*	*	H	α-helix	trans	-67.9	-43	171.9	-78.7	-166.2	174.3	-163.3	0	112.1	V413 L414 K420 R421	V413-K417 WeakPolarHBondContact O-CB 3.01Å; V413-K417 WeakPolarHBondContact O-CG 3.48Å; V413-K417 PolarHBondContact O-N 3.09Å; L414-K417 PolarHBondContact O-N 2.9Å; K417-K420 PolarHBondContact O-N 2.93Å; K417-R421 PolarHBondContact O-N 2.92Å
418	M	52.8	Low	52.5	Low	115 Å²	115	112.4 Å²	112.4	57%	0.567	56%	0.557	S	S	*	*	H	α-helix	trans	-67	-42.1	175.2	-71.3	-174.4	82	0	0	111.6	L414 K420 R421 V422	L414-M418 HydrophobicContact CG-SD 4.38Å; L414-M418 WeakPolarHBondContact O-CB 3.17Å; L414-M418 VanDerWaalsContact O-CG 3.28Å; L414-M418 WeakPolarHBondContact O-CG 3.49Å; L414-M418 PolarHBondContact O-N 3.44Å; M418-K420 VanDerWaalsContact C-N 3.32Å; M418-K420 PolarHBondContact O-N 3.38Å; M418-R421 PolarHBondContact O-N 2.73Å; M418-V422 WeakPolarHBondContact O-CB 3.13Å; M418-V422 VanDerWaalsContact O-CG2 3.26Å; M418-V422 WeakPolarHBondContact O-CG2 3.02Å; M418-V422 PolarHBondContact O-N 2.81Å
419	K	59.6	Low	51.5	Low	157 Å²	157	117.2 Å²	117.2	68%	0.683	58%	0.584	S	S	*	*	H	α-helix	trans	-63.7	-37.1	174.6	-168.3	175.1	-176.9	-177.7	0	111.8	K415 V423	K415-K419 WeakPolarHBondContact O-CB 3.49Å; K415-K419 PolarHBondContact O-N 3.23Å; K419-V423 HydrophobicContact CG-CG2 4.43Å; K419-V423 WeakPolarHBondContact O-CB 3.47Å; K419-V423 WeakPolarHBondContact O-CG2 3.39Å; K419-V423 PolarHBondContact O-N 2.88Å
420	K	54.5	Low	51	Low	158 Å²	158	115.2 Å²	115.2	69%	0.687	59%	0.588	S	S	*	*	H	α-helix	trans	-65.9	-40.6	172.2	-79.1	-179.7	177.8	-167.7	0	112.7	S416 K417 M418 S424	S416-K420 WeakPolarHBondContact O-CB 3.41Å; S416-K420 VanDerWaalsContact O-CG 3.25Å; S416-K420 WeakPolarHBondContact O-CG 3.39Å; S416-K420 PolarHBondContact O-N 3.01Å; K417-K420 PolarHBondContact O-N 2.93Å; M418-K420 VanDerWaalsContact C-N 3.32Å; M418-K420 PolarHBondContact O-N 3.38Å; K420-S424 WeakPolarHBondContact O-CB 3.47Å; K420-S424 PolarHBondContact O-N 3.33Å
421	R	53.9	Low	50.6	Low	191 Å²	191	118.8 Å²	118.8	72%	0.721	61%	0.608	S	S	*	*	H	α-helix	trans	-68.2	-40.4	175.8	-78.2	-170.5	177	-175.7	-1.9	112.3	K417 M418 S424 I425	K417-R421 PolarHBondContact O-N 2.92Å; M418-R421 PolarHBondContact O-N 2.73Å; R421-S424 PolarHBondContact O-N 3.05Å; R421-I425 WeakPolarHBondContact O-CB 3.32Å; R421-I425 WeakPolarHBondContact O-CD1 3.32Å; R421-I425 WeakPolarHBondContact O-CG1 3.37Å; R421-I425 PolarHBondContact O-N 3.02Å
422	V	54.6	Low	50.1	Low	88 Å²	88	120.3 Å²	120.3	53%	0.533	63%	0.625	S	S	.	*	H	α-helix	trans	-67.5	-42.5	176.8	172.1	0	0	0	0	111.1	M418 I425 V426	M418-V422 WeakPolarHBondContact O-CB 3.13Å; M418-V422 VanDerWaalsContact O-CG2 3.26Å; M418-V422 WeakPolarHBondContact O-CG2 3.02Å; M418-V422 PolarHBondContact O-N 2.81Å; V422-I425 PolarHBondContact O-N 3.17Å; V422-V426 VanDerWaalsContact O-CG2 3.3Å; V422-V426 WeakPolarHBondContact O-CG2 3.39Å; V422-V426 PolarHBondContact O-N 3.07Å
423	V	53.7	Low	49.2	Very low	71 Å²	71	120.8 Å²	120.8	43%	0.43	64%	0.635	S	S	.	*	H	α-helix	trans	-65.3	-40.1	174.7	172.5	0	0	0	0	111.2	K419 I425 V426 E427	K419-V423 HydrophobicContact CG-CG2 4.43Å; K419-V423 WeakPolarHBondContact O-CB 3.47Å; K419-V423 WeakPolarHBondContact O-CG2 3.39Å; K419-V423 PolarHBondContact O-N 2.88Å; V423-I425 VanDerWaalsContact C-N 3.27Å; V423-I425 PolarHBondContact O-N 2.91Å; V423-V426 PolarHBondContact O-N 3.21Å; V423-E427 WeakPolarHBondContact O-CB 3.01Å; V423-E427 PolarHBondContact O-N 2.82Å
424	S	49	Very low	49	Very low	81 Å²	81	124.7 Å²	124.7	57%	0.566	65%	0.653	S	S	*	*	H	α-helix	trans	-65.8	-24.3	175.5	178.8	0	0	0	0	114.5	K420 R421	K420-S424 WeakPolarHBondContact O-CB 3.47Å; K420-S424 PolarHBondContact O-N 3.33Å; R421-S424 PolarHBondContact O-N 3.05Å
425	I	50	Low	48.4	Very low	122 Å²	122	124.7 Å²	124.7	63%	0.626	67%	0.666	S	S	*	*	H	α-helix	trans	-86.6	-32.8	177.2	-70.9	164.9	0	0	0	110.4	R421 V422 V423	R421-I425 WeakPolarHBondContact O-CB 3.32Å; R421-I425 WeakPolarHBondContact O-CD1 3.32Å; R421-I425 WeakPolarHBondContact O-CG1 3.37Å; R421-I425 PolarHBondContact O-N 3.02Å; V422-I425 PolarHBondContact O-N 3.17Å; V423-I425 VanDerWaalsContact C-N 3.27Å; V423-I425 PolarHBondContact O-N 2.91Å
426	V	50	Low	47.5	Very low	112 Å²	112	124.5 Å²	124.5	68%	0.679	68%	0.676	S	S	*	*	H	α-helix	trans	-75.1	-24.6	176.5	172.5	0	0	0	0	112.4	V422 V423 A428	V422-V426 VanDerWaalsContact O-CG2 3.3Å; V422-V426 WeakPolarHBondContact O-CG2 3.39Å; V422-V426 PolarHBondContact O-N 3.07Å; V423-V426 PolarHBondContact O-N 3.21Å; V426-A428 VanDerWaalsContact C-N 3.33Å
427	E	47.8	Very low	46.8	Very low	158 Å²	158	128 Å²	128	74%	0.738	69%	0.689	S	S	*	*	T	Hydrogen-bonded Turn	trans	-88.2	0.2	177.2	-146.4	125.2	-170.6	0	0	113.4	V423	V423-E427 WeakPolarHBondContact O-CB 3.01Å; V423-E427 PolarHBondContact O-N 2.82Å
428	A	42.1	Very low	46	Very low	66 Å²	66	129 Å²	129	55%	0.545	70%	0.696	S	S	.	*	T	Hydrogen-bonded Turn	trans	-94.8	3.8	-176	0	0	0	0	0	114.5	V426 P430	V426-A428 VanDerWaalsContact C-N 3.33Å; A428-P430 VanDerWaalsContact O-CD 3.24Å; A428-P430 WeakPolarHBondContact O-CD 3.22Å
429	D	33.8	Very low	45.1	Very low	144 Å²	144	130.1 Å²	130.1	77%	0.77	70%	0.704	S	S	*	*			trans	-103.4	99	169.9	-75.1	-31.2	0	0	0	110.3	M431	D429-M431 PolarHBondContact O-N 2.81Å
430	P	38.7	Very low	44.4	Very low	123 Å²	123	127 Å²	127	80%	0.799	70%	0.702	S	S	*	*			trans	-80.9	104.3	168.6	31.2	-29.5	0	0	0	109.2	A428	A428-P430 VanDerWaalsContact O-CD 3.24Å; A428-P430 WeakPolarHBondContact O-CD 3.22Å
431	M	38	Very low	43.8	Very low	181 Å²	181	130.6 Å²	130.6	89%	0.892	71%	0.711	S	S	*	*			trans	-81.4	130.5	157.1	-101.7	177.6	70.8	0	0	109.1	D429 N433	D429-M431 PolarHBondContact O-N 2.81Å; M431-N433 PolarHBondContact O-N 3.35Å
432	P	43.6	Very low	42.9	Very low	111 Å²	111	129 Å²	129	72%	0.721	72%	0.715	S	S	*	*			trans	-83.6	104.1	178.8	32.8	-28.3	0	0	0	108.4
433	N	39.1	Very low	42.1	Very low	156 Å²	156	131.5 Å²	131.5	83%	0.834	73%	0.726	S	S	*	*			trans	171.5	120.4	135	-91.8	-19	0	0	0	111.4	M431	M431-N433 PolarHBondContact O-N 3.35Å
434	N	48.5	Very low	41.3	Very low	158 Å²	158	133.8 Å²	133.8	85%	0.845	74%	0.742	S	S	*	*			trans	16.5	106	153.1	-77.9	-6.7	0	0	0	118.9
435	A	38.8	Very low	40.7	Very low	87 Å²	87	139.7 Å²	139.7	72%	0.719	76%	0.758	S	S	*	*				-157.3	101.3	129.6	0	0	0	0	0	109.3	I437	A435-I437 PolarHBondContact O-N 2.99Å; A435-I437 VanDerWaalsContact O-N 3.09Å
436	V	38.4	Very low	40.3	Very low	139 Å²	139	145 Å²	145	84%	0.842	77%	0.77	S	S	*	*			trans	-71.2	98.9	171.1	176.1	0	0	0	0	108
437	I	41.1	Very low	39.5	Very low	130 Å²	130	146.7 Å²	146.7	67%	0.667	78%	0.775	S	S	*	*			trans	-98.6	102.2	167.7	-59.1	177.7	0	0	0	107.7	A435 N439	A435-I437 PolarHBondContact O-N 2.99Å; A435-I437 VanDerWaalsContact O-N 3.09Å; I437-N439 PolarHBondContact O-N 3.23Å
438	H	37.8	Very low	38.9	Very low	161 Å²	161	148.7 Å²	148.7	75%	0.745	78%	0.781	S	S	*	*			trans	-76.4	88.3	176.8	-168.5	-80.6	0	0	0	110.4	S440	H438-S440 PolarHBondContact O-N 3.26Å
439	N	35.2	Very low	38.5	Very low	139 Å²	139	155.8 Å²	155.8	74%	0.743	80%	0.8	S	S	*	*			trans	-84.7	95.3	168.7	-75	-30.5	0	0	0	109.8	I437 W441	I437-N439 PolarHBondContact O-N 3.23Å; N439-W441 PolarHBondContact O-N 2.91Å
440	S	44.3	Very low	38.4	Very low	91 Å²	91	154.7 Å²	154.7	64%	0.636	80%	0.798	S	S	*	*			trans	-58.6	95.3	165.6	171.8	0	0	0	0	109.6	H438	H438-S440 PolarHBondContact O-N 3.26Å
441	W	40.6	Very low	38.3	Very low	233 Å²	233	154.6 Å²	154.6	88%	0.883	80%	0.798	S	S	*	*			trans	-172.8	63.4	157.2	-101.2	103.4	0	0	0	109.7	N439	N439-W441 PolarHBondContact O-N 2.91Å
442	I	36.2	Very low	37.8	Very low	158 Å²	158	154.9 Å²	154.9	81%	0.81	79%	0.79	S	S	*	*			trans	-135.2	97.7	165.5	-59.3	176	0	0	0	107.9	P444	I442-P444 WeakPolarHBondContact O-CD 3.18Å
443	D	36.9	Very low	37.4	Very low	140 Å²	140	158.4 Å²	158.4	75%	0.749	80%	0.797	S	S	*	*	P	Polyproline II helix	trans	-61	124.2	160.7	-91.6	-40.5	0	0	0	109	K445	D443-K445 PolarHBondContact O-N 2.87Å
444	P	38	Very low	37	Very low	119 Å²	119	157.3 Å²	157.3	77%	0.773	79%	0.791	S	S	*	*	P	Polyproline II helix	trans	-72.6	127	177.7	26.6	-29.2	0	0	0	110.4	I442 R446	I442-P444 WeakPolarHBondContact O-CD 3.18Å; P444-R446 PolarHBondContact O-N 2.83Å
445	K	35.4	Very low	36.2	Very low	206 Å²	206	154.7 Å²	154.7	90%	0.896	79%	0.785	S	S	*	*	P	Polyproline II helix	trans	-57.3	120.2	174.8	-78	173	179.4	162.7	0	111.4	D443 N447	D443-K445 PolarHBondContact O-N 2.87Å; K445-N447 PolarHBondContact O-N 2.98Å; K445-N447 VanDerWaalsContact O-N 3.12Å
446	R	41.1	Very low	35.8	Very low	234 Å²	234	159 Å²	159	88%	0.883	79%	0.79	S	S	*	*	S	Bend	trans	-50.5	105.9	153.3	-162.5	178.3	-172.6	177.4	2.9	110.4	P444	P444-R446 PolarHBondContact O-N 2.83Å
447	N	34.4	Very low	35.5	Very low	147 Å²	147	160 Å²	160	79%	0.786	79%	0.789	S	S	*	*			trans	153.4	92.6	141.5	-84.1	-5.1	0	0	0	111.3	K445	K445-N447 PolarHBondContact O-N 2.98Å; K445-N447 VanDerWaalsContact O-N 3.12Å
448	K	34.4	Very low	35.1	Very low	199 Å²	199	164.8 Å²	164.8	87%	0.865	80%	0.799	S	S	*	*			trans	-138	116.7	138.5	-92.4	-174	176	-178.4	0	106.9	V450	K448-V450 PolarHBondContact O-N 3.04Å
449	K	34	Very low	34.9	Very low	215 Å²	215	165.2 Å²	165.2	94%	0.935	80%	0.801	S	S	*	*	P	Polyproline II helix	trans	-66.5	124.9	164.5	-70	-179.3	175.3	-173.2	0	106.4
450	V	32.9	Very low	34.8	Very low	121 Å²	121	167.4 Å²	167.4	73%	0.733	80%	0.804	S	S	*	*	P	Polyproline II helix	trans	-96.5	125.3	169.9	178.7	0	0	0	0	106.1	K448	K448-V450 PolarHBondContact O-N 3.04Å
451	P	35.1	Very low	34.1	Very low	122 Å²	122	169 Å²	169	79%	0.792	81%	0.813	S	S	*	*	P	Polyproline II helix	trans	-86.1	126	159.9	31.6	-22.6	0	0	0	107.9
452	Y	28.4	Very low	33.7	Very low	187 Å²	187	165.6 Å²	165.6	73%	0.733	81%	0.812	S	S	*	*			trans	-138.4	109.5	165.5	-160.3	-97.1	0	0	0	106.7	D454	Y452-D454 HydrophobicContact CD1-CB 4.36Å; Y452-D454 HydrophobicContact CE1-CB 4.11Å; Y452-D454 WeakPolarHBondContact CE1-OD2 3.5Å
453	E	34.4	Very low	33.5	Very low	184 Å²	184	164.3 Å²	164.3	86%	0.86	81%	0.811	S	S	*	*			trans	-68.4	135.9	159.9	-79	-167.7	138.9	0	0	107.9
454	D	30.5	Very low	33.6	Very low	134 Å²	134	163 Å²	163	72%	0.717	81%	0.81	S	S	*	*			trans	-145.3	114.4	149.3	-115.2	-6.7	0	0	0	107.5	Y452	Y452-D454 HydrophobicContact CD1-CB 4.36Å; Y452-D454 HydrophobicContact CE1-CB 4.11Å; Y452-D454 WeakPolarHBondContact CE1-OD2 3.5Å
455	S	31.6	Very low	33.5	Very low	102 Å²	102	165.7 Å²	165.7	71%	0.713	81%	0.813	S	S	*	*			trans	-76.9	139.1	172.9	44.2	0	0	0	0	110.8
456	E	31.9	Very low	33.4	Very low	177 Å²	177	162.7 Å²	162.7	83%	0.827	81%	0.811	S	S	*	*			trans	64	115.3	157.4	-69.5	-179.7	140.6	0	0	118.4
457	I	31.7	Very low	33.3	Very low	160 Å²	160	156.5 Å²	156.5	82%	0.821	80%	0.799	S	S	*	*				174.9	139.8	114.3	-84.7	153.8	0	0	0	108.9
458	R	33	Very low	33.3	Very low	232 Å²	232	155.1 Å²	155.1	88%	0.875	80%	0.796	S	S	*	*			trans	89.9	67.9	169.6	-83.5	174.7	179	-157.9	-1.5	118.4
459	E	32.4	Very low	33.5	Very low	169 Å²	169	156.6 Å²	156.6	79%	0.79	81%	0.813	S	S	*	*				-15	149.8	109	-105.1	-171.5	171.4	0	0	116.9
460	K	33.8	Very low	33.5	Very low	186 Å²	186	153.7 Å²	153.7	81%	0.809	81%	0.807	S	S	*	*			trans	100.2	77.3	167	-61.3	176.5	-175.4	-178.4	0	116.2
461	C	29.1	Very low	33.5	Very low	123 Å²	123	155.4 Å²	155.4	83%	0.831	81%	0.811	S	S	*	*				-35.5	137.6	122.1	-66.3	0	0	0	0	111
462	L	32.9	Very low	33.4	Very low	163 Å²	163	157.2 Å²	157.2	85%	0.853	81%	0.812	S	S	*	*				178.7	140.1	128.3	-95.4	166.3	0	0	0	109.5
463	V	31.1	Very low	33.7	Very low	131 Å²	131	155.5 Å²	155.5	79%	0.794	82%	0.817	S	S	*	*			trans	155.7	142.6	134.9	166.9	0	0	0	0	107.3
464	P	39.8	Very low	33.7	Very low	113 Å²	113	153.7 Å²	153.7	73%	0.734	81%	0.814	S	S	*	*			cis	-123.6	154	10.8	12.8	11.8	0	0	0	116.4
465	Q	34.8	Very low	33.9	Very low	175 Å²	175	155 Å²	155	82%	0.818	82%	0.821	S	S	*	*			trans	-64.6	142.9	151.9	-73	-175.4	-33.7	0	0	110.8
466	V	33.7	Very low	34	Very low	142 Å²	142	158.8 Å²	158.8	86%	0.861	83%	0.828	S	S	*	*			trans	-134.1	124.7	143	178.3	0	0	0	0	107.2
467	V	38.7	Very low	34.2	Very low	105 Å²	105	157.4 Å²	157.4	64%	0.636	83%	0.828	S	S	*	*			trans	-100.1	167.7	172.9	168.9	0	0	0	0	108.1
468	T	34.7	Very low	34.4	Very low	118 Å²	118	157.2 Å²	157.2	72%	0.724	83%	0.829	S	S	*	*			trans	99.2	122.7	173.1	72.3	0	0	0	0	112.8
469	D	38.8	Very low	34.5	Very low	229 Å²	229	150.4 Å²	150.4	100%	1.225	83%	0.825	S	S	*	*			cis	-154.9	0	-4.3	-99.1	-23.2	0	0	0	106.6

Retrieved 469 of 469 residues in 225.3 ms (Link to these results)

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