A0A061I667_CRIGR Loading...

Endothelin-1 receptor

Receptor for endothelin-1. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of binding affinities for ET-A is: ET1 > ET2 >> ET3.

AlphaFold DB , UniProt , Accession A0A061I667, Species CRIGR (Cricetulus griseus, Chinese hamster), Gene Ednra, Length 427 aa.

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(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	33.4	Very low	39.9	Very low	168 Å²	168	92.7 Å²	92.7	83%	0.828	49%	0.493	S	S	*	.				0	-46.6	0	-150.3	157.3	74.6	0	0	108	T3 F4 C5	M1-T3 PolarHBondContact O-N 3.09Å; M1-F4 PolarHBondContact O-N 3.48Å; M1-F4 VanDerWaalsContact O-N 3.12Å; M1-C5 PolarHBondContact O-N 3.48Å
2	D	32.4	Very low	40.5	Very low	128 Å²	128	94 Å²	94	68%	0.684	50%	0.499	S	S	*	.	H	α-helix	trans	-61.3	-42.7	178.5	-46.7	-45.7	0	0	0	114	F4 L6	D2-F4 VanDerWaalsContact C-N 3.27Å; D2-F4 PolarHBondContact O-N 3.35Å; D2-L6 WeakPolarHBondContact O-CB 3.41Å; D2-L6 PolarHBondContact O-N 3.42Å
3	T	38	Very low	40.8	Very low	101 Å²	101	91.5 Å²	91.5	62%	0.62	50%	0.5	S	S	*	.	H	α-helix	trans	-69	-25	176.5	-29	0	0	0	0	113.4	M1 L6 M7	M1-T3 PolarHBondContact O-N 3.09Å; T3-L6 WeakPolarHBondContact O-CB 3.4Å; T3-L6 PolarHBondContact O-N 3.06Å; T3-M7 PolarHBondContact O-N 3.13Å
4	F	41.6	Very low	41.1	Very low	66 Å²	66	90.4 Å²	90.4	29%	0.289	49%	0.492	S	S	.	.	H	α-helix	trans	-82.7	-41.2	179.5	175.9	-93.8	0	0	0	111	M1 D2 L6 M7 A8 I314	M1-F4 PolarHBondContact O-N 3.48Å; M1-F4 VanDerWaalsContact O-N 3.12Å; D2-F4 VanDerWaalsContact C-N 3.27Å; D2-F4 PolarHBondContact O-N 3.35Å; F4-L6 PolarHBondContact O-N 2.82Å; F4-M7 PolarHBondContact O-N 2.8Å; F4-A8 WeakPolarHBondContact O-CB 3.26Å; F4-A8 PolarHBondContact O-N 2.83Å; F4-I314 HydrophobicContact CE1-CG1 4.07Å; F4-I314 HydrophobicContact CE2-CD1 3.59Å; F4-I314 HydrophobicContact CE2-CG1 3.53Å; F4-I314 HydrophobicContact CZ-CB 4.46Å; F4-I314 HydrophobicContact CZ-CD1 3.7Å; F4-I314 HydrophobicContact CZ-CG1 3.13Å
5	C	35.3	Very low	41.1	Very low	70 Å²	70	87.1 Å²	87.1	47%	0.473	48%	0.476	S	S	.	.	H	α-helix	trans	-56.9	-40.4	162.7	-77.9	0	0	0	0	110.3	M1 M7 A8 S9	M1-C5 PolarHBondContact O-N 3.48Å; C5-M7 PolarHBondContact O-N 3.04Å; C5-A8 PolarHBondContact O-N 3.13Å; C5-S9 WeakPolarHBondContact O-CA 3.35Å; C5-S9 WeakPolarHBondContact O-CB 3.49Å; C5-S9 PolarHBondContact O-N 3.46Å; C5-S9 PolarHBondContact O-OG 3.2Å
6	L	39.5	Very low	41	Very low	119 Å²	119	83.8 Å²	83.8	62%	0.623	47%	0.468	S	S	*	.	H	α-helix	trans	-63.7	-39	176.8	-114.9	132.8	0	0	0	113.6	D2 T3 F4 F10	D2-L6 WeakPolarHBondContact O-CB 3.41Å; D2-L6 PolarHBondContact O-N 3.42Å; T3-L6 WeakPolarHBondContact O-CB 3.4Å; T3-L6 PolarHBondContact O-N 3.06Å; F4-L6 PolarHBondContact O-N 2.82Å; L6-F10 WeakPolarHBondContact O-CA 3.33Å; L6-F10 WeakPolarHBondContact O-CB 3.37Å; L6-F10 PolarHBondContact O-N 3.34Å
7	M	41.1	Very low	40.6	Very low	78 Å²	78	81.4 Å²	81.4	38%	0.384	47%	0.467	S	S	.	.	H	α-helix	trans	-69.8	-46.8	173.7	-73.3	-136	82	0	0	111.5	T3 F4 C5 S9 F10 W11	T3-M7 PolarHBondContact O-N 3.13Å; F4-M7 PolarHBondContact O-N 2.8Å; C5-M7 PolarHBondContact O-N 3.04Å; M7-S9 VanDerWaalsContact C-N 3.3Å; M7-S9 PolarHBondContact O-N 3.2Å; M7-F10 PolarHBondContact O-N 3.45Å; M7-W11 WeakPolarHBondContact O-CB 3.35Å; M7-W11 PolarHBondContact O-N 2.86Å
8	A	41.3	Very low	40.5	Very low	30 Å²	30	80.6 Å²	80.6	25%	0.248	46%	0.464	C	S	.	.	H	α-helix	trans	-60.1	-41.3	175.8	0	0	0	0	0	111.5	F4 C5 L12	F4-A8 WeakPolarHBondContact O-CB 3.26Å; F4-A8 PolarHBondContact O-N 2.83Å; C5-A8 PolarHBondContact O-N 3.13Å; A8-L12 WeakPolarHBondContact O-CB 3.08Å; A8-L12 WeakPolarHBondContact O-CD1 3.47Å; A8-L12 WeakPolarHBondContact O-CG 3.32Å; A8-L12 PolarHBondContact O-N 2.99Å
9	S	41.4	Very low	40.4	Very low	67 Å²	67	81.6 Å²	81.6	47%	0.469	46%	0.462	S	S	.	.	H	α-helix	trans	-70.8	-36.2	175.2	-65.6	0	0	0	0	112.5	C5 M7 W11 A13	C5-S9 WeakPolarHBondContact O-CA 3.35Å; C5-S9 WeakPolarHBondContact O-CB 3.49Å; C5-S9 PolarHBondContact O-N 3.46Å; C5-S9 PolarHBondContact O-OG 3.2Å; M7-S9 VanDerWaalsContact C-N 3.3Å; M7-S9 PolarHBondContact O-N 3.2Å; S9-W11 VanDerWaalsContact C-N 3.35Å; S9-A13 WeakPolarHBondContact O-CA 3.38Å; S9-A13 WeakPolarHBondContact O-CB 3.46Å; S9-A13 PolarHBondContact O-N 3.33Å
10	F	44.1	Very low	39.9	Very low	118 Å²	118	82.4 Å²	82.4	52%	0.518	47%	0.473	S	S	.	.	H	α-helix	trans	-66	-40.4	174.6	178.5	-100.8	0	0	0	110.7	L6 M7 A13 L14	L6-F10 WeakPolarHBondContact O-CA 3.33Å; L6-F10 WeakPolarHBondContact O-CB 3.37Å; L6-F10 PolarHBondContact O-N 3.34Å; M7-F10 PolarHBondContact O-N 3.45Å; F10-A13 PolarHBondContact O-N 3.35Å; F10-L14 HydrophobicContact CD1-CD1 3.97Å; F10-L14 HydrophobicContact CE1-CD1 3.46Å; F10-L14 VanDerWaalsContact CE1-CD1 3.46Å; F10-L14 HydrophobicContact CE2-CD1 4.48Å; F10-L14 HydrophobicContact CZ-CD1 3.75Å; F10-L14 WeakPolarHBondContact O-CB 3.35Å; F10-L14 PolarHBondContact O-N 2.9Å
11	W	50.8	Low	39.5	Very low	75 Å²	75	85.5 Å²	85.5	28%	0.284	49%	0.488	S	S	.	.	H	α-helix	trans	-75.9	-38.7	176.3	-67.5	119.5	0	0	0	112.7	M7 S9 A13 L14 V15	M7-W11 WeakPolarHBondContact O-CB 3.35Å; M7-W11 PolarHBondContact O-N 2.86Å; S9-W11 VanDerWaalsContact C-N 3.35Å; W11-A13 VanDerWaalsContact C-N 3.27Å; W11-A13 PolarHBondContact O-N 2.85Å; W11-L14 HydrophobicContact CE3-CB 4.36Å; W11-L14 HydrophobicContact CE3-CD1 3.81Å; W11-L14 HydrophobicContact CZ3-CD1 3.8Å; W11-L14 PolarHBondContact O-N 3.15Å; W11-V15 VanDerWaalsContact O-CG2 3.31Å; W11-V15 WeakPolarHBondContact O-CG2 3.14Å; W11-V15 PolarHBondContact O-N 3.38Å
12	L	47	Very low	39.5	Very low	108 Å²	108	81.9 Å²	81.9	57%	0.565	47%	0.472	S	S	*	.	H	α-helix	trans	-65.3	-29.5	169.4	-75.3	166.1	0	0	0	112	A8 G16	A8-L12 WeakPolarHBondContact O-CB 3.08Å; A8-L12 WeakPolarHBondContact O-CD1 3.47Å; A8-L12 WeakPolarHBondContact O-CG 3.32Å; A8-L12 PolarHBondContact O-N 2.99Å; L12-G16 WeakPolarHBondContact O-CA 3.3Å; L12-G16 PolarHBondContact O-N 3.32Å
13	A	45.1	Very low	39.3	Very low	62 Å²	62	81.6 Å²	81.6	51%	0.512	48%	0.477	S	S	.	.	H	α-helix	trans	-79.8	-29.7	173.4	0	0	0	0	0	112.1	S9 F10 W11 G16 G17	S9-A13 WeakPolarHBondContact O-CA 3.38Å; S9-A13 WeakPolarHBondContact O-CB 3.46Å; S9-A13 PolarHBondContact O-N 3.33Å; F10-A13 PolarHBondContact O-N 3.35Å; W11-A13 VanDerWaalsContact C-N 3.27Å; W11-A13 PolarHBondContact O-N 2.85Å; A13-G16 PolarHBondContact O-N 2.9Å; A13-G17 WeakPolarHBondContact O-CA 3.43Å; A13-G17 PolarHBondContact O-N 3.13Å
14	L	44.4	Very low	38.9	Very low	75 Å²	75	84.6 Å²	84.6	39%	0.393	48%	0.484	S	S	.	.	H	α-helix	trans	-67.3	-40.8	168.6	-114.2	141.4	0	0	0	111	F10 W11 V18	F10-L14 HydrophobicContact CD1-CD1 3.97Å; F10-L14 HydrophobicContact CE1-CD1 3.46Å; F10-L14 VanDerWaalsContact CE1-CD1 3.46Å; F10-L14 HydrophobicContact CE2-CD1 4.48Å; F10-L14 HydrophobicContact CZ-CD1 3.75Å; F10-L14 WeakPolarHBondContact O-CB 3.35Å; F10-L14 PolarHBondContact O-N 2.9Å; W11-L14 HydrophobicContact CE3-CB 4.36Å; W11-L14 HydrophobicContact CE3-CD1 3.81Å; W11-L14 HydrophobicContact CZ3-CD1 3.8Å; W11-L14 PolarHBondContact O-N 3.15Å; L14-V18 WeakPolarHBondContact O-CG2 3.31Å
15	V	41.4	Very low	38.2	Very low	41 Å²	41	90.9 Å²	90.9	25%	0.248	51%	0.506	C	S	.	.	H	α-helix	trans	-71.9	-38.1	172.8	174.3	0	0	0	0	111	W11 F19 I353	W11-V15 VanDerWaalsContact O-CG2 3.31Å; W11-V15 WeakPolarHBondContact O-CG2 3.14Å; W11-V15 PolarHBondContact O-N 3.38Å; V15-F19 HydrophobicContact CG1-CE2 4.25Å; V15-F19 WeakPolarHBondContact O-CD2 3.42Å; V15-I353 HydrophobicContact CG1-CD1 4.23Å; V15-I353 HydrophobicContact CG1-CG2 4.08Å
16	G	38.7	Very low	37.9	Very low	34 Å²	34	98.7 Å²	98.7	35%	0.351	53%	0.527	S	S	.	.	H	α-helix	trans	-73.3	-33.2	179.1	0	0	0	0	0	114.2	L12 A13 V18 F19 S20	L12-G16 WeakPolarHBondContact O-CA 3.3Å; L12-G16 PolarHBondContact O-N 3.32Å; A13-G16 PolarHBondContact O-N 2.9Å; G16-V18 PolarHBondContact O-N 3.48Å; G16-F19 WeakPolarHBondContact O-CB 3.33Å; G16-F19 PolarHBondContact O-N 2.83Å; G16-S20 PolarHBondContact O-N 2.89Å
17	G	34.2	Very low	37.4	Very low	43 Å²	43	98.1 Å²	98.1	44%	0.443	53%	0.533	S	S	.	.	H	α-helix	trans	-65.7	-25.7	175.4	0	0	0	0	0	112.6	A13 F19 S20	A13-G17 WeakPolarHBondContact O-CA 3.43Å; A13-G17 PolarHBondContact O-N 3.13Å; G17-F19 VanDerWaalsContact C-N 3.28Å; G17-F19 PolarHBondContact O-N 3.36Å; G17-S20 PolarHBondContact O-N 3.28Å
18	V	40.1	Very low	36.9	Very low	68 Å²	68	99.7 Å²	99.7	41%	0.412	55%	0.547	S	S	.	.	T	Hydrogen-bonded Turn	trans	-70.7	-24.1	172.2	177.3	0	0	0	0	112.1	L14 G16 I82	L14-V18 WeakPolarHBondContact O-CG2 3.31Å; G16-V18 PolarHBondContact O-N 3.48Å; V18-I82 HydrophobicContact CG1-CD1 4.44Å; V18-I82 HydrophobicContact CG2-CD1 3.74Å
19	F	37.8	Very low	36.2	Very low	100 Å²	100	106 Å²	106	44%	0.439	58%	0.577	S	S	.	*	T	Hydrogen-bonded Turn	trans	-83.8	-13.3	174.3	-71	-81.8	0	0	0	113.4	V15 G16 G17 L349 I353	V15-F19 HydrophobicContact CG1-CE2 4.25Å; V15-F19 WeakPolarHBondContact O-CD2 3.42Å; G16-F19 WeakPolarHBondContact O-CB 3.33Å; G16-F19 PolarHBondContact O-N 2.83Å; G17-F19 VanDerWaalsContact C-N 3.28Å; G17-F19 PolarHBondContact O-N 3.36Å; F19-L349 HydrophobicContact CE1-CD2 3.68Å; F19-L349 HydrophobicContact CZ-CD2 3.92Å; F19-I353 HydrophobicContact CE2-CD1 3.88Å; F19-I353 HydrophobicContact CZ-CD1 3.65Å
20	S	30.9	Very low	35.6	Very low	96 Å²	96	111.6 Å²	111.6	67%	0.671	60%	0.6	S	S	*	*			trans	-88.1	-6.1	-176.8	-163.5	0	0	0	0	114.2	G16 G17 N22	G16-S20 PolarHBondContact O-N 2.89Å; G17-S20 PolarHBondContact O-N 3.28Å; S20-N22 VanDerWaalsContact C-N 3.33Å; S20-N22 PolarHBondContact O-N 3.1Å; S20-N22 VanDerWaalsContact O-N 3.15Å
21	D	31.1	Very low	34.8	Very low	149 Å²	149	110.9 Å²	110.9	80%	0.797	61%	0.61	S	S	*	*	S	Bend	trans	-86.6	79.2	169.7	-88.1	-23	0	0	0	110.7
22	N	32.2	Very low	33.7	Very low	91 Å²	91	112.3 Å²	112.3	49%	0.487	63%	0.632	S	S	.	*			trans	63.4	103.6	152.3	-96.4	-33.5	0	0	0	120.8	S20	S20-N22 VanDerWaalsContact C-N 3.33Å; S20-N22 PolarHBondContact O-N 3.1Å; S20-N22 VanDerWaalsContact O-N 3.15Å
23	P	29.6	Very low	32.7	Very low	122 Å²	122	115.7 Å²	115.7	79%	0.792	64%	0.644	S	S	*	*	S	Bend	trans	-84	-13.7	152.5	-4.8	23.4	0	0	0	113.8
24	E	28.8	Very low	32	Very low	164 Å²	164	119 Å²	119	77%	0.766	66%	0.657	S	S	*	*	S	Bend	trans	-99.3	-0.4	-162.9	-72.4	-167.8	153.2	0	0	116.5
25	R	26.2	Very low	31	Very low	199 Å²	199	124.2 Å²	124.2	75%	0.751	68%	0.68	S	S	*	*	S	Bend	trans	-104.9	30.3	-174.7	-150.5	-177.9	-80.5	-165.4	-4.4	115.3
26	Y	30.1	Very low	30.4	Very low	234 Å²	234	129.2 Å²	129.2	92%	0.918	71%	0.705	S	S	*	*	S	Bend	trans	-131.7	10.5	177.8	-96.9	-81.9	0	0	0	115.6
27	S	28.4	Very low	29.6	Very low	106 Å²	106	137.5 Å²	137.5	74%	0.741	73%	0.732	S	S	*	*	S	Bend	trans	-100.9	9.8	178.4	48	0	0	0	0	114.9
28	T	30.3	Very low	29.4	Very low	111 Å²	111	141.7 Å²	141.7	68%	0.681	75%	0.749	S	S	*	*	S	Bend	trans	-134.4	114.4	172.3	40.9	0	0	0	0	110.4
29	N	26.3	Very low	28.7	Very low	163 Å²	163	143.6 Å²	143.6	87%	0.872	76%	0.763	S	S	*	*			trans	127.4	61.5	165.4	-61.7	-22.1	0	0	0	112.3
30	L	29.1	Very low	28	Very low	184 Å²	184	149.5 Å²	149.5	96%	0.963	78%	0.784	S	S	*	*			trans	-120.1	72.3	154.1	-158.9	76	0	0	0	109
31	S	28.9	Very low	27.8	Very low	104 Å²	104	150.7 Å²	150.7	73%	0.727	79%	0.79	S	S	*	*			trans	-146.2	129	152.3	72.5	0	0	0	0	109.8
32	S	26.7	Very low	27.4	Very low	105 Å²	105	147 Å²	147	73%	0.734	79%	0.787	S	S	*	*			trans	91.7	130.3	161.4	82.5	0	0	0	0	118.8
33	H	25.1	Very low	27.1	Very low	179 Å²	179	148 Å²	148	83%	0.829	80%	0.796	S	S	*	*			trans	85.6	96.2	158.1	-71	-70.9	0	0	0	120.7
34	V	31.7	Very low	26.9	Very low	130 Å²	130	147.2 Å²	147.2	79%	0.788	78%	0.782	S	S	*	*			trans	-43.5	128.1	136.8	174.7	0	0	0	0	110.4
35	E	23.3	Very low	27.1	Very low	185 Å²	185	143.6 Å²	143.6	86%	0.864	76%	0.764	S	S	*	*			trans	-173.7	147.3	130.2	-102.9	174.3	-170.1	0	0	111.3
36	D	28.1	Very low	27.3	Very low	147 Å²	147	136.5 Å²	136.5	79%	0.786	74%	0.741	S	S	*	*			trans	-46.7	139.9	-178.2	-82.5	-50.4	0	0	0	114.7
37	F	22.7	Very low	27.4	Very low	207 Å²	207	127.2 Å²	127.2	91%	0.908	71%	0.705	S	S	*	*			trans	-163.3	117.3	137.9	-99.1	-73	0	0	0	110
38	T	30.4	Very low	27.7	Very low	132 Å²	132	124.9 Å²	124.9	81%	0.81	68%	0.684	S	S	*	*			trans	-75.6	136.4	160	42.5	0	0	0	0	108.8
39	P	25.6	Very low	27.7	Very low	107 Å²	107	121.4 Å²	121.4	70%	0.695	67%	0.671	S	S	*	*				-144.9	136.1	119.9	25.1	-4.6	0	0	0	114.6
40	Y	21.6	Very low	28.1	Very low	224 Å²	224	117.8 Å²	117.8	88%	0.878	65%	0.654	S	S	*	*			trans	55.2	115.4	155.4	-77.2	-89	0	0	0	120.4	G42	Y40-G42 PolarHBondContact O-N 2.64Å
41	P	27.4	Very low	28.3	Very low	122 Å²	122	112.7 Å²	112.7	79%	0.792	63%	0.631	S	S	*	*			trans	-85.2	95.8	173.1	32.8	-27.9	0	0	0	111.1	T43	P41-T43 PolarHBondContact O-N 2.87Å
42	G	22	Very low	28.4	Very low	72 Å²	72	113.6 Å²	113.6	74%	0.742	62%	0.624	S	S	*	*			trans	-70.6	116.3	157.5	0	0	0	0	0	109.6	Y40 E44	Y40-G42 PolarHBondContact O-N 2.64Å; G42-E44 PolarHBondContact O-N 3.02Å
43	T	26.5	Very low	28.4	Very low	112 Å²	112	118 Å²	118	69%	0.687	62%	0.624	S	S	*	*			trans	-82.9	96.9	-166.8	-21	0	0	0	0	111.6	P41 F45	P41-T43 PolarHBondContact O-N 2.87Å; T43-F45 HydrophobicContact CG2-CD2 3.56Å; T43-F45 HydrophobicContact CG2-CE2 3.23Å; T43-F45 HydrophobicContact CG2-CZ 4.15Å
44	E	26.1	Very low	28.7	Very low	105 Å²	105	113.8 Å²	113.8	49%	0.491	61%	0.612	S	S	.	*			trans	-100.1	94.7	166.7	-75	-158.9	154.4	0	0	110.6	G42 S77	G42-E44 PolarHBondContact O-N 3.02Å; E44-S77 PolarHBondContact OE1-OG 3.35Å; E44-S77 PolarHBondContact OE2-OG 3.15Å
45	F	31.7	Very low	28.8	Very low	88 Å²	88	112.2 Å²	112.2	39%	0.386	60%	0.603	S	S	.	*			trans	-81.4	121.7	171	-80.4	-83.8	0	0	0	110.5	T43 H236	T43-F45 HydrophobicContact CG2-CD2 3.56Å; T43-F45 HydrophobicContact CG2-CE2 3.23Å; T43-F45 HydrophobicContact CG2-CZ 4.15Å; F45-H236 AromaticContact CE1-CE1 3.93Å
46	N	31.6	Very low	29.4	Very low	49 Å²	49	110.7 Å²	110.7	26%	0.262	60%	0.601	S	S	.	*			trans	-112.2	98.2	169.5	-75.2	-18.9	0	0	0	108.8	K80	N46-K80 WeakPolarHBondContact OD1-CE 3.24Å; N46-K80 PolarHBondContact OD1-NZ 3.14Å
47	F	32.7	Very low	29.4	Very low	40 Å²	40	111.5 Å²	111.5	18%	0.175	60%	0.604	C	S	.	*			trans	-104.1	95.9	179.1	-159.3	-95.9	0	0	0	111.2	G144 F229 T238	F47-G144 WeakPolarHBondContact CB-O 3.4Å; F47-F229 HydrophobicContact CD1-CE1 4.31Å; F47-F229 AromaticContact CD1-CZ 3.96Å; F47-F229 HydrophobicContact CD1-CZ 3.96Å; F47-F229 HydrophobicContact CD2-CE1 4.48Å; F47-F229 AromaticContact CD2-CE2 3.72Å; F47-F229 HydrophobicContact CD2-CE2 3.72Å; F47-F229 AromaticContact CD2-CZ 3.46Å; F47-F229 HydrophobicContact CD2-CZ 3.46Å; F47-F229 VanDerWaalsContact CD2-CZ 3.46Å; F47-F229 HydrophobicContact CE1-CD1 4.4Å; F47-F229 AromaticContact CE1-CE1 3.44Å; F47-F229 HydrophobicContact CE1-CE1 3.44Å; F47-F229 VanDerWaalsContact CE1-CE1 3.44Å; F47-F229 HydrophobicContact CE1-CE2 4.26Å; F47-F229 AromaticContact CE1-CZ 3.38Å; F47-F229 HydrophobicContact CE1-CZ 3.38Å; F47-F229 HydrophobicContact CE2-CD1 4.48Å; F47-F229 AromaticContact CE2-CD2 3.85Å; F47-F229 HydrophobicContact CE2-CD2 3.85Å; F47-F229 AromaticContact CE2-CE1 3.71Å; F47-F229 HydrophobicContact CE2-CE1 3.71Å; F47-F229 AromaticContact CE2-CE2 2.91Å; F47-F229 HydrophobicContact CE2-CE2 2.91Å; F47-F229 AromaticContact CE2-CZ 2.84Å; F47-F229 HydrophobicContact CE2-CZ 2.84Å; F47-F229 HydrophobicContact CG-CZ 4.02Å; F47-F229 AromaticContact CZ-CD1 3.82Å; F47-F229 HydrophobicContact CZ-CD1 3.82Å; F47-F229 AromaticContact CZ-CD2 3.94Å; F47-F229 HydrophobicContact CZ-CD2 3.94Å; F47-F229 AromaticContact CZ-CE1 3.1Å; F47-F229 HydrophobicContact CZ-CE1 3.1Å; F47-F229 AromaticContact CZ-CE2 3.26Å; F47-F229 HydrophobicContact CZ-CE2 3.26Å; F47-F229 HydrophobicContact CZ-CG 4.21Å; F47-F229 AromaticContact CZ-CZ 2.78Å; F47-F229 HydrophobicContact CZ-CZ 2.78Å; F47-T238 HydrophobicContact CE1-CG2 3.61Å; F47-T238 WeakPolarHBondContact CE1-OG1 3.31Å; F47-T238 HydrophobicContact CZ-CG2 4.19Å
48	L	34.3	Very low	29.8	Very low	57 Å²	57	108.1 Å²	108.1	30%	0.298	60%	0.6	S	S	.	*			trans	-123.7	82.9	162.5	-137.3	76.8	0	0	0	108.4	T50 L348 Y352	L48-T50 PolarHBondContact O-N 3.08Å; L48-L348 HydrophobicContact CD2-CD2 4.09Å; L48-Y352 WeakPolarHBondContact CD1-OH 3.04Å; L48-Y352 HydrophobicContact CD2-CE2 3.74Å
49	G	29.9	Very low	29.6	Very low	38 Å²	38	109 Å²	109	39%	0.392	60%	0.6	S	S	.	*			trans	-53	122.4	175	0	0	0	0	0	111.2
50	T	34	Very low	29.7	Very low	87 Å²	87	109.5 Å²	109.5	53%	0.534	60%	0.603	S	S	.	*			trans	-62.7	130	171.2	44.8	0	0	0	0	110.5	L48 H52	L48-T50 PolarHBondContact O-N 3.08Å; T50-H52 VanDerWaalsContact C-N 3.33Å; T50-H52 PolarHBondContact O-N 2.86Å
51	T	33.9	Very low	30.4	Very low	77 Å²	77	103.4 Å²	103.4	47%	0.472	59%	0.593	S	S	.	*	S	Bend	trans	-72.7	82.7	166.5	47.6	0	0	0	0	110.1
52	H	30.6	Very low	30.6	Very low	123 Å²	123	104.7 Å²	104.7	57%	0.569	59%	0.593	S	S	*	*			trans	-160.2	112	155.5	-137.1	-125.6	0	0	0	108.8	T50 E335	T50-H52 VanDerWaalsContact C-N 3.33Å; T50-H52 PolarHBondContact O-N 2.86Å; H52-E335 IonicContact CE1-OE1 3.49Å; H52-E335 PolarHBondContact CE1-OE1 3.04Å; H52-E335 IonicContact CG-OE1 2.73Å; H52-E335 IonicContact ND1-OE1 3.18Å; H52-E335 PolarHBondContact ND1-OE1 3.16Å
53	R	27.9	Very low	31.3	Very low	197 Å²	197	105.4 Å²	105.4	74%	0.743	60%	0.6	S	S	*	*			trans	-105.8	122.7	161.4	-172.2	-175.9	-160.9	-167.7	4.8	105.4	T55	R53-T55 PolarHBondContact O-N 3.17Å
54	P	31.8	Very low	31.5	Very low	90 Å²	90	105.1 Å²	105.1	58%	0.584	60%	0.603	S	S	*	*			trans	-69.3	126.8	173.5	26.5	-29.7	0	0	0	109.1
55	T	32.7	Very low	31.9	Very low	97 Å²	97	108 Å²	108	60%	0.595	62%	0.618	S	S	*	*			trans	-75.6	123.3	173.5	-6.9	0	0	0	0	109.2	R53	R53-T55 PolarHBondContact O-N 3.17Å
56	N	35.3	Very low	32.2	Very low	153 Å²	153	110.2 Å²	110.2	82%	0.818	63%	0.63	S	S	*	*			trans	47.6	93.2	159.7	-57.6	-45.6	0	0	0	117.6
57	L	28.5	Very low	32.8	Very low	164 Å²	164	111 Å²	111	86%	0.859	64%	0.639	S	S	*	*			trans	-129.9	111.5	154.4	-114	140.4	0	0	0	109.1	L59	L57-L59 PolarHBondContact O-N 3.1Å
58	V	30.9	Very low	33.7	Very low	136 Å²	136	118.7 Å²	118.7	82%	0.824	67%	0.669	S	S	*	*			trans	-52.9	126	163.7	171.8	0	0	0	0	107.4	P60	V58-P60 WeakPolarHBondContact O-CD 3.42Å
59	L	26.8	Very low	34.6	Very low	152 Å²	152	118 Å²	118	80%	0.796	67%	0.668	S	S	*	*			trans	-52.6	139.7	176.6	-118.8	87.9	0	0	0	110.6	L57	L57-L59 PolarHBondContact O-N 3.1Å
60	P	27.3	Very low	35.4	Very low	116 Å²	116	122.3 Å²	122.3	75%	0.753	69%	0.689	S	S	*	*				-116.1	134.7	121.4	19.9	-6.2	0	0	0	110.3	V58 N62	V58-P60 WeakPolarHBondContact O-CD 3.42Å; P60-N62 PolarHBondContact O-N 3.4Å; P60-N62 VanDerWaalsContact O-N 3.11Å
61	S	36.6	Very low	36	Very low	96 Å²	96	124.7 Å²	124.7	67%	0.671	69%	0.694	S	S	*	*			trans	-41	106	166.6	158.6	0	0	0	0	112.9
62	N	31.4	Very low	36.6	Very low	150 Å²	150	125.8 Å²	125.8	80%	0.802	69%	0.694	S	S	*	*	S	Bend		165.2	113.6	129.8	-91.5	-12.2	0	0	0	111.3	P60 S64	P60-N62 PolarHBondContact O-N 3.4Å; P60-N62 VanDerWaalsContact O-N 3.11Å; N62-S64 PolarHBondContact O-N 2.85Å
63	G	37.4	Very low	37.5	Very low	87 Å²	87	122.6 Å²	122.6	90%	0.897	68%	0.683	S	S	*	*			trans	74.7	22.4	137.3	0	0	0	0	0	121	M65	G63-M65 PolarHBondContact O-N 3.39Å
64	S	31	Very low	38.6	Very low	106 Å²	106	121.3 Å²	121.3	74%	0.741	68%	0.683	S	S	*	*			trans	-95.6	88.2	165.3	54.8	0	0	0	0	111.1	N62 H66	N62-S64 PolarHBondContact O-N 2.85Å; S64-H66 PolarHBondContact O-N 3.3Å
65	M	34.1	Very low	40	Very low	165 Å²	165	118.4 Å²	118.4	81%	0.813	66%	0.662	S	S	*	*			trans	-57.8	105.7	164.4	-162.1	165	84.9	0	0	107.2	G63 S67	G63-M65 PolarHBondContact O-N 3.39Å; M65-S67 VanDerWaalsContact C-N 3.26Å; M65-S67 PolarHBondContact O-N 2.89Å
66	H	38.5	Very low	41.7	Very low	134 Å²	134	118.1 Å²	118.1	62%	0.62	66%	0.66	S	S	*	*			trans	-57.9	98.9	165.5	-101.2	-78.6	0	0	0	106.3	S64 Y68	S64-H66 PolarHBondContact O-N 3.3Å; H66-Y68 VanDerWaalsContact O-CD2 3.25Å; H66-Y68 WeakPolarHBondContact O-CD2 3.15Å; H66-Y68 PolarHBondContact O-N 3.39Å
67	S	44.1	Very low	43.6	Very low	67 Å²	67	113.7 Å²	113.7	47%	0.469	64%	0.641	S	S	.	*			trans	-66.3	97.5	-178.9	-86.3	0	0	0	0	108.5	M65 R340	M65-S67 VanDerWaalsContact C-N 3.26Å; M65-S67 PolarHBondContact O-N 2.89Å; S67-R340 PolarHBondContact O-NH2 3.48Å
68	Y	51.1	Low	46	Very low	201 Å²	201	108.5 Å²	108.5	79%	0.788	62%	0.622	S	S	*	*			trans	-52.9	141.9	159.1	-60	-84.6	0	0	0	108.4	H66 P70	H66-Y68 VanDerWaalsContact O-CD2 3.25Å; H66-Y68 WeakPolarHBondContact O-CD2 3.15Å; H66-Y68 PolarHBondContact O-N 3.39Å; Y68-P70 VanDerWaalsContact O-CD 3.26Å; Y68-P70 WeakPolarHBondContact O-CD 3.38Å
69	C	53.5	Low	48.3	Very low	43 Å²	43	103.4 Å²	103.4	29%	0.291	59%	0.589	S	S	.	*			trans	-56.7	117.5	173	-80	0	0	0	0	108.6	Q71 C341	C69-Q71 PolarHBondContact O-N 3.28Å; C69-C341 WeakPolarHBondContact CA-SG 3.2Å; C69-C341 HydrophobicContact CB-CB 3.83Å; C69-C341 WeakPolarHBondContact CB-SG 3.17Å; C69-C341 WeakPolarHBondContact SG-CA 3.28Å; C69-C341 WeakPolarHBondContact SG-CB 3.38Å; C69-C341 CovalentContact SG-SG 2.04Å; C69-C341 PolarHBondContact SG-SG 3.49Å
70	P	46.3	Very low	51	Low	128 Å²	128	97 Å²	97	83%	0.831	55%	0.554	S	S	*	*	S	Bend	trans	-70.6	-20.6	-176.3	27.9	-33.6	0	0	0	111.4	Y68 Q72	Y68-P70 VanDerWaalsContact O-CD 3.26Å; Y68-P70 WeakPolarHBondContact O-CD 3.38Å; P70-Q72 PolarHBondContact O-N 3.43Å
71	Q	47.3	Very low	53.7	Low	136 Å²	136	99.5 Å²	99.5	64%	0.636	55%	0.55	S	S	*	*	S	Bend	trans	-82.2	103.5	176.9	-145.1	163.2	9.5	0	0	108.7	C69 T73	C69-Q71 PolarHBondContact O-N 3.28Å; Q71-T73 PolarHBondContact O-N 3.3Å; Q71-T73 VanDerWaalsContact O-N 3.13Å
72	Q	45.5	Very low	56	Low	101 Å²	101	97.5 Å²	97.5	47%	0.472	53%	0.531	S	S	.	.			trans	-58.5	118	168.8	-170.1	161.2	-0.4	0	0	107.3	P70 K74	P70-Q72 PolarHBondContact O-N 3.43Å; Q72-K74 PolarHBondContact O-N 2.66Å
73	T	49.3	Very low	58.5	Low	55 Å²	55	90.8 Å²	90.8	34%	0.337	50%	0.496	S	S	.	.			trans	-62.4	89.8	163.7	37.3	0	0	0	0	106.8	Q71 I75 S345 L348	Q71-T73 PolarHBondContact O-N 3.3Å; Q71-T73 VanDerWaalsContact O-N 3.13Å; T73-I75 PolarHBondContact O-N 2.83Å; T73-S345 WeakPolarHBondContact CG2-OG 3.42Å; T73-L348 HydrophobicContact CG2-CD1 4.37Å
74	K	51.5	Low	60.8	Low	171 Å²	171	87.8 Å²	87.8	74%	0.743	46%	0.46	S	S	*	.			trans	-68.1	90.1	168.7	-73.9	-173.6	-180	-179.1	0	105.4	Q72 T76	Q72-K74 PolarHBondContact O-N 2.66Å; K74-T76 PolarHBondContact O-N 3.34Å
75	I	61	Low	63.6	Low	29 Å²	29	85.9 Å²	85.9	15%	0.149	44%	0.444	C	S	.	.			trans	-60	99	157.4	-59.8	178.9	0	0	0	104.2	T73 S77 F79 K80 Y352	T73-I75 PolarHBondContact O-N 2.83Å; I75-S77 PolarHBondContact O-N 2.82Å; I75-F79 HydrophobicContact CG2-CB 3.94Å; I75-F79 HydrophobicContact CG2-CD1 3.32Å; I75-F79 HydrophobicContact CG2-CE1 4.17Å; I75-F79 HydrophobicContact CG2-CG 3.95Å; I75-K80 HydrophobicContact CG2-CG 3.92Å; I75-Y352 HydrophobicContact CD1-CE2 3.75Å
76	T	69.1	Low	66.2	Low	90 Å²	90	79.3 Å²	79.3	55%	0.552	41%	0.412	S	S	*	.			trans	-52.8	140.1	-177.8	-47.3	0	0	0	0	108.6	K74 A78 F79 K80	K74-T76 PolarHBondContact O-N 3.34Å; T76-A78 HydrophobicContact CG2-CB 3.87Å; T76-A78 PolarHBondContact O-N 3.47Å; T76-F79 WeakPolarHBondContact O-CA 3.03Å; T76-F79 WeakPolarHBondContact O-CB 3.22Å; T76-F79 PolarHBondContact O-N 3.07Å; T76-K80 PolarHBondContact O-N 3.49Å
77	S	75.1	Confident	68.5	Low	61 Å²	61	73.2 Å²	73.2	43%	0.427	39%	0.385	S	S	.	.	H	α-helix	trans	-53.8	-29.6	176.5	-40.3	0	0	0	0	111.4	E44 I75 F79 K80 Y81	E44-S77 PolarHBondContact OE1-OG 3.35Å; E44-S77 PolarHBondContact OE2-OG 3.15Å; I75-S77 PolarHBondContact O-N 2.82Å; S77-F79 PolarHBondContact O-N 3.13Å; S77-K80 PolarHBondContact O-N 3.25Å; S77-Y81 WeakPolarHBondContact O-CB 3.49Å; S77-Y81 PolarHBondContact O-N 3.33Å
78	A	78.8	Confident	70.7	Confident	55 Å²	55	73.1 Å²	73.1	46%	0.455	38%	0.383	S	S	.	.	H	α-helix	trans	-56	-46	168.9	0	0	0	0	0	113.4	T76 Y81 I82	T76-A78 HydrophobicContact CG2-CB 3.87Å; T76-A78 PolarHBondContact O-N 3.47Å; A78-Y81 PolarHBondContact O-N 3.34Å; A78-I82 WeakPolarHBondContact O-CB 3.43Å; A78-I82 WeakPolarHBondContact O-CD1 3.32Å; A78-I82 WeakPolarHBondContact O-CG1 3.48Å; A78-I82 PolarHBondContact O-N 2.98Å
79	F	79.6	Confident	72.6	Confident	28 Å²	28	66.5 Å²	66.5	12%	0.123	36%	0.363	C	S	.	.	H	α-helix	trans	-64	-42.8	178	-178.3	-90.1	0	0	0	112.1	I75 T76 S77 Y81 T83 L349 Y352	I75-F79 HydrophobicContact CG2-CB 3.94Å; I75-F79 HydrophobicContact CG2-CD1 3.32Å; I75-F79 HydrophobicContact CG2-CE1 4.17Å; I75-F79 HydrophobicContact CG2-CG 3.95Å; T76-F79 WeakPolarHBondContact O-CA 3.03Å; T76-F79 WeakPolarHBondContact O-CB 3.22Å; T76-F79 PolarHBondContact O-N 3.07Å; S77-F79 PolarHBondContact O-N 3.13Å; F79-Y81 VanDerWaalsContact C-N 3.33Å; F79-Y81 PolarHBondContact O-N 2.85Å; F79-T83 WeakPolarHBondContact CE1-OG1 3.24Å; F79-T83 VanDerWaalsContact O-CB 3.26Å; F79-T83 WeakPolarHBondContact O-CB 3.3Å; F79-T83 PolarHBondContact O-N 2.95Å; F79-T83 PolarHBondContact O-OG1 2.91Å; F79-L349 HydrophobicContact CD2-CD1 3.81Å; F79-L349 HydrophobicContact CE2-CD1 3.3Å; F79-L349 HydrophobicContact CZ-CD1 3.87Å; F79-Y352 HydrophobicContact CE1-CD1 4.29Å; F79-Y352 HydrophobicContact CE1-CD2 4.34Å; F79-Y352 HydrophobicContact CE1-CG 4.01Å; F79-Y352 HydrophobicContact CZ-CG 4.07Å
80	K	81.4	Confident	74.4	Confident	17 Å²	17	64.7 Å²	64.7	7%	0.074	35%	0.351	C	S	.	.	H	α-helix	trans	-59.9	-46.3	175	-67.5	-175.9	178.6	178.7	0	110.8	N46 I75 T76 S77 T84 L141	N46-K80 WeakPolarHBondContact OD1-CE 3.24Å; N46-K80 PolarHBondContact OD1-NZ 3.14Å; I75-K80 HydrophobicContact CG2-CG 3.92Å; T76-K80 PolarHBondContact O-N 3.49Å; S77-K80 PolarHBondContact O-N 3.25Å; K80-T84 VanDerWaalsContact O-CB 3.28Å; K80-T84 WeakPolarHBondContact O-CB 3.45Å; K80-T84 PolarHBondContact O-N 3.44Å; K80-T84 PolarHBondContact O-OG1 3.04Å; K80-L141 HydrophobicContact CG-CD1 4.33Å; K80-L141 HydrophobicContact CG-CG 4.46Å
81	Y	84.9	Confident	76.6	Confident	169 Å²	169	62.2 Å²	62.2	66%	0.663	33%	0.327	S	S	*	.	H	α-helix	trans	-61.8	-50.9	179.9	-173.5	-97.4	0	0	0	111.5	S77 A78 F79 T83 T84 V85	S77-Y81 WeakPolarHBondContact O-CB 3.49Å; S77-Y81 PolarHBondContact O-N 3.33Å; A78-Y81 PolarHBondContact O-N 3.34Å; F79-Y81 VanDerWaalsContact C-N 3.33Å; F79-Y81 PolarHBondContact O-N 2.85Å; Y81-T83 PolarHBondContact O-N 3.41Å; Y81-T84 PolarHBondContact O-N 3.46Å; Y81-V85 HydrophobicContact CD1-CG2 4.23Å; Y81-V85 HydrophobicContact CE1-CG2 3.92Å; Y81-V85 WeakPolarHBondContact O-CG2 3.37Å; Y81-V85 PolarHBondContact O-N 2.92Å
82	I	85.7	Confident	78.7	Confident	54 Å²	54	60.7 Å²	60.7	28%	0.277	32%	0.323	S	S	.	.	H	α-helix	trans	-58.5	-50.2	178.6	-68.3	163.7	0	0	0	110.9	V18 A78 T84 V85 I86	V18-I82 HydrophobicContact CG1-CD1 4.44Å; V18-I82 HydrophobicContact CG2-CD1 3.74Å; A78-I82 WeakPolarHBondContact O-CB 3.43Å; A78-I82 WeakPolarHBondContact O-CD1 3.32Å; A78-I82 WeakPolarHBondContact O-CG1 3.48Å; A78-I82 PolarHBondContact O-N 2.98Å; I82-T84 VanDerWaalsContact C-N 3.29Å; I82-T84 PolarHBondContact O-N 3.32Å; I82-V85 PolarHBondContact O-N 2.95Å; I82-I86 HydrophobicContact CG2-CD1 3.76Å; I82-I86 HydrophobicContact CG2-CG1 4.49Å; I82-I86 WeakPolarHBondContact O-CG1 3.38Å; I82-I86 PolarHBondContact O-N 3.24Å
83	T	83	Confident	80.9	Confident	9 Å²	9	58.5 Å²	58.5	6%	0.055	32%	0.316	C	S	.	.	H	α-helix	trans	-61.3	-38.9	179.9	-61.1	0	0	0	0	111.9	F79 Y81 S87 L141 N356	F79-T83 WeakPolarHBondContact CE1-OG1 3.24Å; F79-T83 VanDerWaalsContact O-CB 3.26Å; F79-T83 WeakPolarHBondContact O-CB 3.3Å; F79-T83 PolarHBondContact O-N 2.95Å; F79-T83 PolarHBondContact O-OG1 2.91Å; Y81-T83 PolarHBondContact O-N 3.41Å; T83-S87 VanDerWaalsContact O-CB 3.31Å; T83-S87 WeakPolarHBondContact O-CB 3.39Å; T83-S87 PolarHBondContact O-N 3.13Å; T83-S87 PolarHBondContact O-OG 3.07Å; T83-L141 HydrophobicContact CG2-CD2 3.38Å; T83-N356 WeakPolarHBondContact CG2-ND2 3.16Å; T83-N356 WeakPolarHBondContact CG2-OD1 3.06Å
84	T	86.9	Confident	83	Confident	24 Å²	24	55.9 Å²	55.9	15%	0.147	30%	0.3	C	S	.	.	H	α-helix	trans	-65.7	-46.8	177	-58.6	0	0	0	0	111.1	K80 Y81 I82 I86 S87 C88 V138 L142	K80-T84 VanDerWaalsContact O-CB 3.28Å; K80-T84 WeakPolarHBondContact O-CB 3.45Å; K80-T84 PolarHBondContact O-N 3.44Å; K80-T84 PolarHBondContact O-OG1 3.04Å; Y81-T84 PolarHBondContact O-N 3.46Å; I82-T84 VanDerWaalsContact C-N 3.29Å; I82-T84 PolarHBondContact O-N 3.32Å; T84-I86 VanDerWaalsContact C-N 3.35Å; T84-I86 PolarHBondContact O-N 2.77Å; T84-S87 PolarHBondContact O-N 3.42Å; T84-C88 PolarHBondContact O-N 3.3Å; T84-C88 PolarHBondContact O-SG 3.45Å; T84-V138 HydrophobicContact CG2-CG1 4.13Å; T84-L142 HydrophobicContact CG2-CD1 4.16Å; T84-L142 WeakPolarHBondContact OG1-CD2 3.38Å
85	V	88.8	Confident	85	Confident	67 Å²	67	50.7 Å²	50.7	41%	0.406	28%	0.279	S	S	.	.	H	α-helix	trans	-60.8	-43.4	177.3	171.8	0	0	0	0	111.5	Y81 I82 C88 T89	Y81-V85 HydrophobicContact CD1-CG2 4.23Å; Y81-V85 HydrophobicContact CE1-CG2 3.92Å; Y81-V85 WeakPolarHBondContact O-CG2 3.37Å; Y81-V85 PolarHBondContact O-N 2.92Å; I82-V85 PolarHBondContact O-N 2.95Å; V85-C88 PolarHBondContact O-N 3.16Å; V85-T89 PolarHBondContact O-N 2.88Å; V85-T89 PolarHBondContact O-OG1 2.94Å
86	I	88.1	Confident	86.5	Confident	26 Å²	26	53 Å²	53	13%	0.133	29%	0.294	C	S	.	.	H	α-helix	trans	-61.1	-48.3	175.3	-69.6	169.8	0	0	0	110.1	I82 T84 C88 T89 I90	I82-I86 HydrophobicContact CG2-CD1 3.76Å; I82-I86 HydrophobicContact CG2-CG1 4.49Å; I82-I86 WeakPolarHBondContact O-CG1 3.38Å; I82-I86 PolarHBondContact O-N 3.24Å; T84-I86 VanDerWaalsContact C-N 3.35Å; T84-I86 PolarHBondContact O-N 2.77Å; I86-C88 PolarHBondContact O-N 3.04Å; I86-T89 WeakPolarHBondContact O-CB 3.39Å; I86-T89 PolarHBondContact O-N 2.9Å; I86-T89 VanDerWaalsContact O-N 3.13Å; I86-I90 HydrophobicContact CG2-CD1 3.69Å; I86-I90 HydrophobicContact CG2-CG1 4.33Å; I86-I90 WeakPolarHBondContact O-CG1 3.41Å; I86-I90 PolarHBondContact O-N 2.89Å
87	S	88.2	Confident	87.7	Confident	7 Å²	7	49.3 Å²	49.3	5%	0.049	27%	0.274	C	S	.	.	H	α-helix	trans	-61.4	-43.5	179.3	-61.7	0	0	0	0	112.1	T83 T84 T89 I90 F91 L134	T83-S87 VanDerWaalsContact O-CB 3.31Å; T83-S87 WeakPolarHBondContact O-CB 3.39Å; T83-S87 PolarHBondContact O-N 3.13Å; T83-S87 PolarHBondContact O-OG 3.07Å; T84-S87 PolarHBondContact O-N 3.42Å; S87-T89 VanDerWaalsContact C-N 3.29Å; S87-T89 PolarHBondContact O-N 3.4Å; S87-I90 PolarHBondContact O-N 3.05Å; S87-F91 WeakPolarHBondContact O-CB 3.28Å; S87-F91 PolarHBondContact O-N 2.91Å; S87-L134 WeakPolarHBondContact O-CD2 3.46Å
88	C	89.8	Confident	88.6	Confident	64 Å²	64	46.4 Å²	46.4	43%	0.432	25%	0.254	S	S	.	.	H	α-helix	trans	-60.7	-39.4	174.6	-70.1	0	0	0	0	112	T84 V85 I86 F91 I92	T84-C88 PolarHBondContact O-N 3.3Å; T84-C88 PolarHBondContact O-SG 3.45Å; V85-C88 PolarHBondContact O-N 3.16Å; I86-C88 PolarHBondContact O-N 3.04Å; C88-F91 WeakPolarHBondContact O-CB 3.17Å; C88-F91 PolarHBondContact O-N 2.96Å; C88-I92 WeakPolarHBondContact O-CG1 3.28Å; C88-I92 PolarHBondContact O-N 3.03Å
89	T	90.5	Very high	89.3	Confident	62 Å²	62	46 Å²	46	38%	0.38	25%	0.251	S	S	.	.	H	α-helix	trans	-65.4	-46.9	176.3	-55.5	0	0	0	0	111.1	V85 I86 S87 F91 I92 V93	V85-T89 PolarHBondContact O-N 2.88Å; V85-T89 PolarHBondContact O-OG1 2.94Å; I86-T89 WeakPolarHBondContact O-CB 3.39Å; I86-T89 PolarHBondContact O-N 2.9Å; I86-T89 VanDerWaalsContact O-N 3.13Å; S87-T89 VanDerWaalsContact C-N 3.29Å; S87-T89 PolarHBondContact O-N 3.4Å; T89-F91 VanDerWaalsContact C-N 3.27Å; T89-F91 PolarHBondContact O-N 2.92Å; T89-I92 PolarHBondContact O-N 2.81Å; T89-V93 HydrophobicContact CG2-CG2 4.28Å; T89-V93 WeakPolarHBondContact O-CB 3.36Å; T89-V93 VanDerWaalsContact O-CG2 3.28Å; T89-V93 WeakPolarHBondContact O-CG2 3.45Å; T89-V93 PolarHBondContact O-N 3.42Å
90	I	91.3	Very high	89.9	Confident	6 Å²	6	45.5 Å²	45.5	3%	0.031	25%	0.25	C	C	.	.	H	α-helix	trans	-59.3	-41	175.8	-67.7	169.2	0	0	0	110.4	I86 S87 G94 L134 M360 C363	I86-I90 HydrophobicContact CG2-CD1 3.69Å; I86-I90 HydrophobicContact CG2-CG1 4.33Å; I86-I90 WeakPolarHBondContact O-CG1 3.41Å; I86-I90 PolarHBondContact O-N 2.89Å; S87-I90 PolarHBondContact O-N 3.05Å; I90-G94 WeakPolarHBondContact O-CA 3.47Å; I90-G94 PolarHBondContact O-N 2.92Å; I90-L134 HydrophobicContact CB-CD2 4.18Å; I90-L134 HydrophobicContact CG2-CD2 3.87Å; I90-M360 HydrophobicContact CD1-CB 4.01Å; I90-M360 HydrophobicContact CD1-CE 4.3Å; I90-M360 HydrophobicContact CD1-CG 4.29Å; I90-M360 HydrophobicContact CG1-CG 4.42Å; I90-C363 HydrophobicContact CG2-CB 4.31Å
91	F	92.1	Very high	90.5	Very high	75 Å²	75	44.8 Å²	44.8	33%	0.329	25%	0.247	S	C	.	.	H	α-helix	trans	-59.6	-53.7	177.5	-175	-97.3	0	0	0	111.5	S87 C88 T89 M95 V130 L134 P135	S87-F91 WeakPolarHBondContact O-CB 3.28Å; S87-F91 PolarHBondContact O-N 2.91Å; C88-F91 WeakPolarHBondContact O-CB 3.17Å; C88-F91 PolarHBondContact O-N 2.96Å; T89-F91 VanDerWaalsContact C-N 3.27Å; T89-F91 PolarHBondContact O-N 2.92Å; F91-M95 HydrophobicContact CD1-CG 4.35Å; F91-M95 HydrophobicContact CE1-CG 4.1Å; F91-M95 HydrophobicContact CE2-CG 4.27Å; F91-M95 HydrophobicContact CZ-CG 4.05Å; F91-M95 VanDerWaalsContact O-CB 3.24Å; F91-M95 WeakPolarHBondContact O-CB 3.37Å; F91-M95 WeakPolarHBondContact O-CG 3.5Å; F91-M95 PolarHBondContact O-N 3.35Å; F91-V130 HydrophobicContact CD2-CG1 3.69Å; F91-V130 WeakPolarHBondContact CD2-O 3.39Å; F91-V130 HydrophobicContact CE2-CG1 4.23Å; F91-V130 WeakPolarHBondContact CE2-O 3.3Å; F91-V130 HydrophobicContact CG-CG1 4.31Å; F91-L134 HydrophobicContact CB-CD2 3.69Å; F91-L134 HydrophobicContact CD2-CD2 4.21Å; F91-L134 HydrophobicContact CG-CD2 4.47Å; F91-P135 HydrophobicContact CD2-CG 4.48Å; F91-P135 HydrophobicContact CE2-CG 4.13Å
92	I	92.2	Very high	90.9	Very high	105 Å²	105	38.8 Å²	38.8	54%	0.538	23%	0.226	S	C	.	.	H	α-helix	trans	-62.4	-50.3	-178.2	-65.9	166.6	0	0	0	110.6	C88 T89 M95 V96	C88-I92 WeakPolarHBondContact O-CG1 3.28Å; C88-I92 PolarHBondContact O-N 3.03Å; T89-I92 PolarHBondContact O-N 2.81Å; I92-M95 PolarHBondContact O-N 3.01Å; I92-V96 WeakPolarHBondContact O-CB 3.46Å; I92-V96 WeakPolarHBondContact O-CG2 3.48Å; I92-V96 PolarHBondContact O-N 3.45Å
93	V	91.9	Very high	91.2	Very high	54 Å²	54	43 Å²	43	33%	0.327	24%	0.238	S	C	.	.	H	α-helix	trans	-66.7	-41.7	-177.6	177	0	0	0	0	111.2	T89 G97 C363 I367	T89-V93 HydrophobicContact CG2-CG2 4.28Å; T89-V93 WeakPolarHBondContact O-CB 3.36Å; T89-V93 VanDerWaalsContact O-CG2 3.28Å; T89-V93 WeakPolarHBondContact O-CG2 3.45Å; T89-V93 PolarHBondContact O-N 3.42Å; V93-G97 WeakPolarHBondContact O-CA 3.37Å; V93-G97 PolarHBondContact O-N 3.06Å; V93-C363 HydrophobicContact CB-CB 4.41Å; V93-C363 HydrophobicContact CG1-CB 4.15Å; V93-I367 HydrophobicContact CG1-CD1 3.92Å
94	G	92.9	Very high	91.5	Very high	0 Å²	0	42.6 Å²	42.6	0%	0	24%	0.236	C	C	.	.	H	α-helix	trans	-63.1	-45.1	177.1	0	0	0	0	0	112.1	I90 N98	I90-G94 WeakPolarHBondContact O-CA 3.47Å; I90-G94 PolarHBondContact O-N 2.92Å; G94-N98 VanDerWaalsContact O-CB 3.28Å; G94-N98 WeakPolarHBondContact O-CB 3.19Å; G94-N98 PolarHBondContact O-N 3.22Å; G94-N98 PolarHBondContact O-ND2 3.06Å
95	M	93.6	Very high	91.7	Very high	63 Å²	63	42 Å²	42	31%	0.31	23%	0.232	S	C	.	.	H	α-helix	trans	-61.5	-56.1	175.7	-76.6	-65.2	-65.6	0	0	111.7	F91 I92 A99 L127 V130 V131	F91-M95 HydrophobicContact CD1-CG 4.35Å; F91-M95 HydrophobicContact CE1-CG 4.1Å; F91-M95 HydrophobicContact CE2-CG 4.27Å; F91-M95 HydrophobicContact CZ-CG 4.05Å; F91-M95 VanDerWaalsContact O-CB 3.24Å; F91-M95 WeakPolarHBondContact O-CB 3.37Å; F91-M95 WeakPolarHBondContact O-CG 3.5Å; F91-M95 PolarHBondContact O-N 3.35Å; I92-M95 PolarHBondContact O-N 3.01Å; M95-A99 WeakPolarHBondContact O-CB 3.45Å; M95-A99 PolarHBondContact O-N 2.7Å; M95-L127 HydrophobicContact SD-CD2 3.92Å; M95-V130 HydrophobicContact CG-CG1 4.03Å; M95-V130 HydrophobicContact SD-CG1 4.42Å; M95-V131 HydrophobicContact CE-CG2 4.13Å; M95-V131 HydrophobicContact SD-CG2 3.36Å; M95-V131 WeakPolarHBondContact SD-CG2 3.47Å
96	V	93	Very high	91.7	Very high	76 Å²	76	46.9 Å²	46.9	46%	0.461	24%	0.244	S	C	.	.	H	α-helix	trans	-64.4	-45.9	-176.9	174.1	0	0	0	0	110.9	I92 T100 L384	I92-V96 WeakPolarHBondContact O-CB 3.46Å; I92-V96 WeakPolarHBondContact O-CG2 3.48Å; I92-V96 PolarHBondContact O-N 3.45Å; V96-T100 WeakPolarHBondContact O-CB 3.33Å; V96-T100 PolarHBondContact O-N 3.28Å; V96-T100 PolarHBondContact O-OG1 2.97Å; V96-L384 HydrophobicContact CG1-CD2 4.27Å
97	G	92.9	Very high	91.7	Very high	14 Å²	14	50.5 Å²	50.5	14%	0.144	26%	0.26	C	S	.	.	H	α-helix	trans	-63.6	-54.2	-177.1	0	0	0	0	0	112.5	V93 T100 L101	V93-G97 WeakPolarHBondContact O-CA 3.37Å; V93-G97 PolarHBondContact O-N 3.06Å; G97-T100 PolarHBondContact O-N 3.37Å; G97-L101 WeakPolarHBondContact O-CB 3.36Å; G97-L101 PolarHBondContact O-N 3.44Å
98	N	94.8	Very high	91.5	Very high	0 Å²	0	53.1 Å²	53.1	0%	0	27%	0.274	C	S	.	.	H	α-helix	trans	-70.9	-37.7	-177.3	-68.9	-62.9	0	0	0	112.2	G94 L101 L102 A123 L127 S362 P366	G94-N98 VanDerWaalsContact O-CB 3.28Å; G94-N98 WeakPolarHBondContact O-CB 3.19Å; G94-N98 PolarHBondContact O-N 3.22Å; G94-N98 PolarHBondContact O-ND2 3.06Å; N98-L101 PolarHBondContact O-N 3.35Å; N98-L102 WeakPolarHBondContact O-CG 3.37Å; N98-L102 PolarHBondContact O-N 2.83Å; N98-A123 HydrophobicContact CB-CB 4.3Å; N98-L127 HydrophobicContact CB-CD1 4.31Å; N98-L127 HydrophobicContact CB-CD2 3.79Å; N98-L127 HydrophobicContact CB-CG 3.66Å; N98-S362 PolarHBondContact ND2-O 2.91Å; N98-P366 HydrophobicContact CB-CG 4.43Å; N98-P366 WeakPolarHBondContact OD1-CD 3.3Å; N98-P366 WeakPolarHBondContact OD1-CG 3.34Å
99	A	94.3	Very high	91.1	Very high	46 Å²	46	57.2 Å²	57.2	38%	0.38	28%	0.284	S	S	.	.	H	α-helix	trans	-64.3	-41.1	174	0	0	0	0	0	111.9	M95 L102 R103	M95-A99 WeakPolarHBondContact O-CB 3.45Å; M95-A99 PolarHBondContact O-N 2.7Å; A99-L102 PolarHBondContact O-N 3.21Å; A99-R103 WeakPolarHBondContact O-CB 3.46Å; A99-R103 PolarHBondContact O-N 3.47Å
100	T	92.3	Very high	90.7	Very high	17 Å²	17	57.3 Å²	57.3	10%	0.104	29%	0.287	C	S	.	.	H	α-helix	trans	-64.8	-40.9	175.5	-59.7	0	0	0	0	111.2	V96 G97 R103 I104 F380 C383 L384	V96-T100 WeakPolarHBondContact O-CB 3.33Å; V96-T100 PolarHBondContact O-N 3.28Å; V96-T100 PolarHBondContact O-OG1 2.97Å; G97-T100 PolarHBondContact O-N 3.37Å; T100-R103 WeakPolarHBondContact O-CB 3.35Å; T100-R103 PolarHBondContact O-N 2.96Å; T100-I104 HydrophobicContact CG2-CD1 3.87Å; T100-I104 HydrophobicContact CG2-CG1 4.34Å; T100-I104 VanDerWaalsContact O-CG1 3.28Å; T100-I104 WeakPolarHBondContact O-CG1 3.28Å; T100-I104 PolarHBondContact O-N 2.96Å; T100-F380 HydrophobicContact CG2-CD1 3.66Å; T100-F380 HydrophobicContact CG2-CE1 3.79Å; T100-C383 HydrophobicContact CG2-CB 4.01Å; T100-L384 HydrophobicContact CG2-CD2 4.22Å; T100-L384 HydrophobicContact CG2-CG 4.27Å
101	L	92.8	Very high	90.2	Very high	2 Å²	2	57.1 Å²	57.1	1%	0.01	29%	0.286	C	S	.	.	H	α-helix	trans	-60.2	-47.5	176.4	-178.7	56.6	0	0	0	111.8	G97 N98 R103 I104 I105 I119 A123 P366 L369 F376 F380	G97-L101 WeakPolarHBondContact O-CB 3.36Å; G97-L101 PolarHBondContact O-N 3.44Å; N98-L101 PolarHBondContact O-N 3.35Å; L101-R103 PolarHBondContact O-N 3.39Å; L101-I104 PolarHBondContact O-N 3.31Å; L101-I105 HydrophobicContact CD1-CD1 4.01Å; L101-I105 HydrophobicContact CG-CD1 4.18Å; L101-I105 WeakPolarHBondContact O-CG1 3.39Å; L101-I105 PolarHBondContact O-N 3.27Å; L101-I105 VanDerWaalsContact O-N 3.14Å; L101-I119 HydrophobicContact CD1-CG2 4.1Å; L101-I119 HydrophobicContact CD2-CG2 3.78Å; L101-I119 HydrophobicContact CG-CG2 4.17Å; L101-A123 HydrophobicContact CD2-CB 3.95Å; L101-A123 HydrophobicContact CG-CB 4.38Å; L101-P366 HydrophobicContact CD2-CG 4.34Å; L101-L369 HydrophobicContact CD1-CD1 4.09Å; L101-L369 HydrophobicContact CD2-CD1 3.69Å; L101-F376 HydrophobicContact CD1-CD1 3.85Å; L101-F376 HydrophobicContact CD1-CE1 3.6Å; L101-F376 HydrophobicContact CD1-CZ 4.5Å; L101-F380 HydrophobicContact CB-CE1 4.48Å; L101-F380 HydrophobicContact CB-CZ 4Å; L101-F380 HydrophobicContact CD1-CE2 4.28Å; L101-F380 HydrophobicContact CD1-CZ 3.98Å
102	L	93.6	Very high	89.9	Confident	44 Å²	44	58 Å²	58	23%	0.23	29%	0.287	C	S	.	.	H	α-helix	trans	-59.8	-45.1	174	-73.2	177.9	0	0	0	111.6	N98 A99 I104 I105 Y106 A120 A123 L127	N98-L102 WeakPolarHBondContact O-CG 3.37Å; N98-L102 PolarHBondContact O-N 2.83Å; A99-L102 PolarHBondContact O-N 3.21Å; L102-I104 PolarHBondContact O-N 3.49Å; L102-I105 PolarHBondContact O-N 2.9Å; L102-Y106 VanDerWaalsContact O-CB 3.3Å; L102-Y106 WeakPolarHBondContact O-CB 3.49Å; L102-Y106 PolarHBondContact O-N 2.96Å; L102-A120 HydrophobicContact CD2-CB 3.8Å; L102-A120 WeakPolarHBondContact CD2-O 3.39Å; L102-A123 HydrophobicContact CD2-CB 4.02Å; L102-A123 HydrophobicContact CG-CB 4Å; L102-L127 HydrophobicContact CD1-CD1 3.5Å
103	R	92.2	Very high	89.5	Confident	142 Å²	142	54.6 Å²	54.6	54%	0.536	27%	0.27	S	S	.	.	H	α-helix	trans	-59.4	-44.7	177.1	-179.4	179.1	173.3	170.9	2.4	112	A99 T100 L101 I105 Y106 Q107	A99-R103 WeakPolarHBondContact O-CB 3.46Å; A99-R103 PolarHBondContact O-N 3.47Å; T100-R103 WeakPolarHBondContact O-CB 3.35Å; T100-R103 PolarHBondContact O-N 2.96Å; L101-R103 PolarHBondContact O-N 3.39Å; R103-I105 PolarHBondContact O-N 3.5Å; R103-Y106 PolarHBondContact O-N 3.31Å; R103-Q107 HydrophobicContact CG-CG 4.18Å; R103-Q107 WeakPolarHBondContact O-CB 3.5Å; R103-Q107 WeakPolarHBondContact O-CG 3.48Å; R103-Q107 PolarHBondContact O-N 3.36Å
104	I	89.9	Confident	89.3	Confident	0 Å²	0	52.3 Å²	52.3	0%	0	26%	0.257	C	S	.	.	H	α-helix	trans	-59.5	-47	178.5	-74.9	164.8	0	0	0	110.8	T100 L101 L102 N108 M111 C379 F380 C383	T100-I104 HydrophobicContact CG2-CD1 3.87Å; T100-I104 HydrophobicContact CG2-CG1 4.34Å; T100-I104 VanDerWaalsContact O-CG1 3.28Å; T100-I104 WeakPolarHBondContact O-CG1 3.28Å; T100-I104 PolarHBondContact O-N 2.96Å; L101-I104 PolarHBondContact O-N 3.31Å; L102-I104 PolarHBondContact O-N 3.49Å; I104-N108 WeakPolarHBondContact O-CB 3.4Å; I104-N108 PolarHBondContact O-N 3.43Å; I104-N108 VanDerWaalsContact O-N 3.1Å; I104-N108 PolarHBondContact O-ND2 3.26Å; I104-M111 HydrophobicContact CG2-CE 4.47Å; I104-C379 HydrophobicContact CB-CB 4.41Å; I104-C379 HydrophobicContact CD1-CB 3.92Å; I104-C379 HydrophobicContact CG1-CB 4.03Å; I104-C379 HydrophobicContact CG2-CB 3.48Å; I104-C379 VanDerWaalsContact CG2-CB 3.48Å; I104-F380 HydrophobicContact CD1-CB 4.34Å; I104-F380 HydrophobicContact CD1-CD1 3.64Å; I104-F380 HydrophobicContact CD1-CD2 4.12Å; I104-F380 HydrophobicContact CD1-CE1 3.9Å; I104-F380 HydrophobicContact CD1-CE2 4.35Å; I104-F380 HydrophobicContact CD1-CG 3.75Å; I104-F380 HydrophobicContact CD1-CZ 4.25Å; I104-C383 HydrophobicContact CG1-CB 4.42Å
105	I	90.5	Very high	88.9	Confident	13 Å²	13	52.8 Å²	52.8	7%	0.067	26%	0.261	C	S	.	.	H	α-helix	trans	-69.3	-39.4	-178.2	-64.4	163.7	0	0	0	110.2	L101 L102 R103 R112 N116 I119 A120 F376	L101-I105 HydrophobicContact CD1-CD1 4.01Å; L101-I105 HydrophobicContact CG-CD1 4.18Å; L101-I105 WeakPolarHBondContact O-CG1 3.39Å; L101-I105 PolarHBondContact O-N 3.27Å; L101-I105 VanDerWaalsContact O-N 3.14Å; L102-I105 PolarHBondContact O-N 2.9Å; R103-I105 PolarHBondContact O-N 3.5Å; I105-R112 WeakPolarHBondContact O-CG 3.4Å; I105-N116 HydrophobicContact CG2-CB 4.49Å; I105-I119 HydrophobicContact CD1-CG2 4.1Å; I105-A120 HydrophobicContact CD1-CB 4.01Å; I105-A120 HydrophobicContact CG2-CB 4.4Å; I105-F376 HydrophobicContact CD1-CE1 4.4Å; I105-F376 HydrophobicContact CG1-CE1 4.26Å
106	Y	89.3	Confident	88.7	Confident	169 Å²	169	50.4 Å²	50.4	66%	0.663	25%	0.249	S	C	*	.	H	α-helix	trans	-64.9	-50.3	176	-178	-100.3	0	0	0	111.4	L102 R103 R112	L102-Y106 VanDerWaalsContact O-CB 3.3Å; L102-Y106 WeakPolarHBondContact O-CB 3.49Å; L102-Y106 PolarHBondContact O-N 2.96Å; R103-Y106 PolarHBondContact O-N 3.31Å; Y106-R112 PolarHBondContact O-NE 3.44Å; Y106-R112 PolarHBondContact O-NH2 3.43Å
107	Q	87.8	Confident	88.7	Confident	102 Å²	102	47.2 Å²	47.2	48%	0.477	23%	0.231	S	C	.	.	H	α-helix	trans	-72.5	-35.7	-173.4	-69.1	-176.6	-27.1	0	0	113.2	R103 K109	R103-Q107 HydrophobicContact CG-CG 4.18Å; R103-Q107 WeakPolarHBondContact O-CB 3.5Å; R103-Q107 WeakPolarHBondContact O-CG 3.48Å; R103-Q107 PolarHBondContact O-N 3.36Å; Q107-K109 PolarHBondContact O-N 3.32Å
108	N	84.1	Confident	88.6	Confident	62 Å²	62	46.6 Å²	46.6	33%	0.332	22%	0.224	S	C	.	.			trans	-92.8	103.7	-174.9	-64.6	-65.9	0	0	0	111.8	I104 C110 M111	I104-N108 WeakPolarHBondContact O-CB 3.4Å; I104-N108 PolarHBondContact O-N 3.43Å; I104-N108 VanDerWaalsContact O-N 3.1Å; I104-N108 PolarHBondContact O-ND2 3.26Å; N108-C110 PolarHBondContact O-N 3Å; N108-C110 VanDerWaalsContact O-N 3.16Å; N108-M111 HydrophobicContact CB-CB 3.99Å; N108-M111 HydrophobicContact CB-CG 3.73Å; N108-M111 WeakPolarHBondContact O-CA 3.21Å; N108-M111 WeakPolarHBondContact O-CB 3.43Å; N108-M111 PolarHBondContact O-N 3.34Å
109	K	82.4	Confident	88.5	Confident	149 Å²	149	47.3 Å²	47.3	65%	0.648	23%	0.228	S	C	*	.	G	3₁₀ helix	trans	-54.1	-36.5	176.4	-67.6	-176.2	-178.7	179.1	0	112.8	Q107 M111 R112	Q107-K109 PolarHBondContact O-N 3.32Å; K109-M111 PolarHBondContact O-N 2.89Å; K109-M111 VanDerWaalsContact O-N 3.17Å; K109-R112 PolarHBondContact O-N 3.05Å; K109-R112 VanDerWaalsContact O-N 3.08Å
110	C	80.2	Confident	88.4	Confident	65 Å²	65	46 Å²	46	44%	0.439	22%	0.217	S	C	.	.	G	3₁₀ helix	trans	-68.3	-8.6	176.5	-54.6	0	0	0	0	114.5	N108 K375	N108-C110 PolarHBondContact O-N 3Å; N108-C110 VanDerWaalsContact O-N 3.16Å; C110-K375 PolarHBondContact O-NZ 2.88Å
111	M	81.4	Confident	88.6	Confident	2 Å²	2	45.6 Å²	45.6	1%	0.01	22%	0.215	C	C	.	.	G	3₁₀ helix	trans	-101.5	-6	174.1	-66.6	-67.3	-84.1	0	0	112.3	I104 N108 K109 N113 N116 K375 F376	I104-M111 HydrophobicContact CG2-CE 4.47Å; N108-M111 HydrophobicContact CB-CB 3.99Å; N108-M111 HydrophobicContact CB-CG 3.73Å; N108-M111 WeakPolarHBondContact O-CA 3.21Å; N108-M111 WeakPolarHBondContact O-CB 3.43Å; N108-M111 PolarHBondContact O-N 3.34Å; K109-M111 PolarHBondContact O-N 2.89Å; K109-M111 VanDerWaalsContact O-N 3.17Å; M111-N113 PolarHBondContact O-N 3.23Å; M111-N113 VanDerWaalsContact O-N 3.07Å; M111-N116 WeakPolarHBondContact O-CB 3.48Å; M111-N116 PolarHBondContact O-ND2 3.11Å; M111-K375 HydrophobicContact CE-CD 4.34Å; M111-K375 HydrophobicContact CE-CG 4.37Å; M111-K375 HydrophobicContact SD-CD 3.42Å; M111-K375 WeakPolarHBondContact SD-CD 3.06Å; M111-K375 WeakPolarHBondContact SD-CE 3.31Å; M111-K375 HydrophobicContact SD-CG 3.84Å; M111-K375 PolarHBondContact SD-NZ 3.15Å; M111-F376 HydrophobicContact CE-CD1 3.58Å; M111-F376 HydrophobicContact CE-CD2 4.3Å; M111-F376 HydrophobicContact CE-CE1 3.27Å; M111-F376 HydrophobicContact CE-CE2 4.03Å; M111-F376 HydrophobicContact CE-CG 4.09Å; M111-F376 HydrophobicContact CE-CZ 3.51Å
112	R	85.5	Confident	88.6	Confident	93 Å²	93	45.7 Å²	45.7	35%	0.351	22%	0.215	S	C	.	.			trans	-85.8	80.7	-179.2	-61.1	-179.2	-174	179.3	-2.7	110.8	I105 Y106 K109 G197	I105-R112 WeakPolarHBondContact O-CG 3.4Å; Y106-R112 PolarHBondContact O-NE 3.44Å; Y106-R112 PolarHBondContact O-NH2 3.43Å; K109-R112 PolarHBondContact O-N 3.05Å; K109-R112 VanDerWaalsContact O-N 3.08Å; R112-G197 CarbonylContact O-C 3.38Å; R112-G197 WeakPolarHBondContact O-CA 3.37Å; R112-G197 PolarHBondContact O-N 3.13Å; R112-G197 VanDerWaalsContact O-N 3.1Å
113	N	85.4	Confident	88.6	Confident	33 Å²	33	43.7 Å²	43.7	18%	0.176	21%	0.205	C	C	.	.	B	Isolated β-bridge	trans	-131.7	169.7	176	61.1	38.1	0	0	0	110.1	M111 P115 N116 A117	M111-N113 PolarHBondContact O-N 3.23Å; M111-N113 VanDerWaalsContact O-N 3.07Å; N113-P115 VanDerWaalsContact OD1-CD 3.3Å; N113-P115 WeakPolarHBondContact OD1-CD 3.48Å; N113-P115 VanDerWaalsContact OD1-CG 3.24Å; N113-P115 WeakPolarHBondContact OD1-CG 3.36Å; N113-N116 PolarHBondContact O-N 3.43Å; N113-N116 WeakPolarHBondContact OD1-CB 3.19Å; N113-N116 PolarHBondContact OD1-N 3.11Å; N113-N116 PolarHBondContact OD1-ND2 3.48Å; N113-A117 PolarHBondContact O-N 2.73Å
114	G	86.3	Confident	88.7	Confident	6 Å²	6	40.5 Å²	40.5	6%	0.062	20%	0.198	C	C	.	.	H	α-helix	trans	-47.5	-58.6	-178.6	0	0	0	0	0	115.5	N116 A117 L118	G114-N116 VanDerWaalsContact C-N 3.32Å; G114-N116 PolarHBondContact O-N 3.35Å; G114-A117 WeakPolarHBondContact O-CB 3.44Å; G114-A117 PolarHBondContact O-N 3.41Å; G114-L118 PolarHBondContact O-N 2.93Å; G114-L118 VanDerWaalsContact O-N 3.11Å
115	P	85.4	Confident	88.9	Confident	11 Å²	11	40.6 Å²	40.6	7%	0.071	20%	0.199	C	C	.	.	H	α-helix	trans	-63.9	-34.9	-178.1	24.4	-35.5	0	0	0	113.5	N113 A117 L118 I119 L179	N113-P115 VanDerWaalsContact OD1-CD 3.3Å; N113-P115 WeakPolarHBondContact OD1-CD 3.48Å; N113-P115 VanDerWaalsContact OD1-CG 3.24Å; N113-P115 WeakPolarHBondContact OD1-CG 3.36Å; P115-A117 VanDerWaalsContact C-N 3.3Å; P115-L118 PolarHBondContact O-N 2.97Å; P115-I119 WeakPolarHBondContact O-CG1 3.48Å; P115-I119 PolarHBondContact O-N 2.92Å; P115-L179 HydrophobicContact CB-CD2 4.34Å
116	N	89.5	Confident	89	Confident	13 Å²	13	40 Å²	40	7%	0.07	20%	0.195	C	C	.	.	H	α-helix	trans	-72	-26.8	175.5	-68.9	-8	0	0	0	111.9	I105 M111 N113 G114 I119 A120 F376	I105-N116 HydrophobicContact CG2-CB 4.49Å; M111-N116 WeakPolarHBondContact O-CB 3.48Å; M111-N116 PolarHBondContact O-ND2 3.11Å; N113-N116 PolarHBondContact O-N 3.43Å; N113-N116 WeakPolarHBondContact OD1-CB 3.19Å; N113-N116 PolarHBondContact OD1-N 3.11Å; N113-N116 PolarHBondContact OD1-ND2 3.48Å; G114-N116 VanDerWaalsContact C-N 3.32Å; G114-N116 PolarHBondContact O-N 3.35Å; N116-I119 PolarHBondContact O-N 2.96Å; N116-A120 WeakPolarHBondContact O-CB 3.41Å; N116-A120 PolarHBondContact O-N 3.06Å; N116-F376 WeakPolarHBondContact OD1-CZ 3.48Å
117	A	91.6	Very high	89.2	Confident	9 Å²	9	33.1 Å²	33.1	7%	0.074	17%	0.17	C	C	.	.	H	α-helix	trans	-68.9	-37	171	0	0	0	0	0	112	N113 G114 P115 A120 S121 I198 T202 I206	N113-A117 PolarHBondContact O-N 2.73Å; G114-A117 WeakPolarHBondContact O-CB 3.44Å; G114-A117 PolarHBondContact O-N 3.41Å; P115-A117 VanDerWaalsContact C-N 3.3Å; A117-A120 WeakPolarHBondContact O-CB 3Å; A117-A120 PolarHBondContact O-N 3.38Å; A117-S121 PolarHBondContact O-N 2.79Å; A117-I198 HydrophobicContact CB-CD1 3.92Å; A117-I198 HydrophobicContact CB-CG1 4.09Å; A117-I198 HydrophobicContact CB-CG2 4.12Å; A117-T202 HydrophobicContact CB-CG2 4.38Å; A117-I206 HydrophobicContact CB-CD1 3.86Å
118	L	92	Very high	89.4	Confident	1 Å²	1	30.5 Å²	30.5	1%	0.005	16%	0.159	C	C	.	.	H	α-helix	trans	-64.5	-41.8	170.8	-67.9	171	0	0	0	111.6	G114 P115 A120 S121 L122 N175 A178 L179 T202 E205 I206 I209	G114-L118 PolarHBondContact O-N 2.93Å; G114-L118 VanDerWaalsContact O-N 3.11Å; P115-L118 PolarHBondContact O-N 2.97Å; L118-A120 VanDerWaalsContact C-N 3.3Å; L118-A120 PolarHBondContact O-N 2.77Å; L118-S121 WeakPolarHBondContact O-CB 3.5Å; L118-S121 PolarHBondContact O-N 3.47Å; L118-L122 PolarHBondContact O-N 3.06Å; L118-N175 PolarHBondContact O-OD1 3.36Å; L118-A178 HydrophobicContact CD1-CB 3.95Å; L118-A178 HydrophobicContact CD2-CB 4Å; L118-L179 HydrophobicContact CB-CD2 3.79Å; L118-L179 HydrophobicContact CB-CG 4.08Å; L118-L179 HydrophobicContact CD1-CD2 4.06Å; L118-L179 HydrophobicContact CD1-CG 4.32Å; L118-T202 HydrophobicContact CG-CG2 4.24Å; L118-E205 HydrophobicContact CD2-CG 4.46Å; L118-I206 HydrophobicContact CD2-CD1 4.47Å; L118-I206 HydrophobicContact CD2-CG1 3.78Å; L118-I209 HydrophobicContact CD2-CD1 4.11Å
119	I	91.9	Very high	89.7	Confident	15 Å²	15	27.9 Å²	27.9	8%	0.077	15%	0.145	C	C	.	.	H	α-helix	trans	-61.6	-38.5	173	-68.9	166.4	0	0	0	111.2	L101 I105 P115 N116 L122 A123 L179 L369 F376	L101-I119 HydrophobicContact CD1-CG2 4.1Å; L101-I119 HydrophobicContact CD2-CG2 3.78Å; L101-I119 HydrophobicContact CG-CG2 4.17Å; I105-I119 HydrophobicContact CD1-CG2 4.1Å; P115-I119 WeakPolarHBondContact O-CG1 3.48Å; P115-I119 PolarHBondContact O-N 2.92Å; N116-I119 PolarHBondContact O-N 2.96Å; I119-L122 WeakPolarHBondContact O-CB 3.25Å; I119-L122 PolarHBondContact O-N 3.34Å; I119-A123 WeakPolarHBondContact O-CB 3.2Å; I119-A123 PolarHBondContact O-N 3.38Å; I119-L179 HydrophobicContact CG1-CD1 4.25Å; I119-L179 HydrophobicContact CG1-CD2 4.13Å; I119-L369 HydrophobicContact CD1-CD2 4.17Å; I119-L369 HydrophobicContact CG2-CD1 3.55Å; I119-F376 HydrophobicContact CD1-CE2 4.01Å; I119-F376 HydrophobicContact CD1-CZ 3.97Å
120	A	93.7	Very high	90.2	Very high	19 Å²	19	20.8 Å²	20.8	16%	0.157	11%	0.114	C	C	.	.	H	α-helix	trans	-67	-40.6	174.8	0	0	0	0	0	112.2	L102 I105 N116 A117 L118 L122 A123 L124	L102-A120 HydrophobicContact CD2-CB 3.8Å; L102-A120 WeakPolarHBondContact CD2-O 3.39Å; I105-A120 HydrophobicContact CD1-CB 4.01Å; I105-A120 HydrophobicContact CG2-CB 4.4Å; N116-A120 WeakPolarHBondContact O-CB 3.41Å; N116-A120 PolarHBondContact O-N 3.06Å; A117-A120 WeakPolarHBondContact O-CB 3Å; A117-A120 PolarHBondContact O-N 3.38Å; L118-A120 VanDerWaalsContact C-N 3.3Å; L118-A120 PolarHBondContact O-N 2.77Å; A120-L122 VanDerWaalsContact C-N 3.33Å; A120-L122 PolarHBondContact O-N 3.04Å; A120-A123 PolarHBondContact O-N 3.4Å; A120-L124 PolarHBondContact O-N 2.94Å
121	S	94.8	Very high	90.7	Very high	8 Å²	8	21.2 Å²	21.2	6%	0.056	11%	0.114	C	C	.	.	H	α-helix	trans	-58.1	-45.6	173.3	-180	0	0	0	0	111.4	A117 L118 L124 G125 N175 W210	A117-S121 PolarHBondContact O-N 2.79Å; L118-S121 WeakPolarHBondContact O-CB 3.5Å; L118-S121 PolarHBondContact O-N 3.47Å; S121-L124 PolarHBondContact O-N 3.39Å; S121-G125 PolarHBondContact O-N 2.89Å; S121-G125 VanDerWaalsContact O-N 3.11Å; S121-N175 PolarHBondContact OG-ND2 3.43Å; S121-N175 PolarHBondContact OG-OD1 3.24Å; S121-W210 PolarHBondContact OG-NE1 3.44Å
122	L	92.6	Very high	91	Very high	4 Å²	4	23.8 Å²	23.8	2%	0.021	13%	0.127	C	C	.	.	H	α-helix	trans	-58.7	-50.3	174.1	178.4	67.1	0	0	0	111.9	L118 I119 A120 L124 G125 D126 T172 N175	L118-L122 PolarHBondContact O-N 3.06Å; I119-L122 WeakPolarHBondContact O-CB 3.25Å; I119-L122 PolarHBondContact O-N 3.34Å; A120-L122 VanDerWaalsContact C-N 3.33Å; A120-L122 PolarHBondContact O-N 3.04Å; L122-L124 VanDerWaalsContact C-N 3.27Å; L122-L124 PolarHBondContact O-N 3.39Å; L122-G125 PolarHBondContact O-N 2.92Å; L122-G125 VanDerWaalsContact O-N 3.14Å; L122-D126 PolarHBondContact O-N 3.47Å; L122-T172 HydrophobicContact CD1-CG2 3.72Å; L122-N175 HydrophobicContact CB-CB 4.29Å; L122-N175 HydrophobicContact CD1-CB 4.46Å
123	A	94.5	Very high	91	Very high	1 Å²	1	19.6 Å²	19.6	1%	0.008	11%	0.112	C	C	.	.	H	α-helix	trans	-61.8	-33.5	179.9	0	0	0	0	0	112.9	N98 L101 L102 I119 A120 L127	N98-A123 HydrophobicContact CB-CB 4.3Å; L101-A123 HydrophobicContact CD2-CB 3.95Å; L101-A123 HydrophobicContact CG-CB 4.38Å; L102-A123 HydrophobicContact CD2-CB 4.02Å; L102-A123 HydrophobicContact CG-CB 4Å; I119-A123 WeakPolarHBondContact O-CB 3.2Å; I119-A123 PolarHBondContact O-N 3.38Å; A120-A123 PolarHBondContact O-N 3.4Å; A123-L127 WeakPolarHBondContact O-CG 3.48Å; A123-L127 PolarHBondContact O-N 2.89Å
124	L	94.6	Very high	91.1	Very high	76 Å²	76	18.2 Å²	18.2	40%	0.398	11%	0.105	S	C	.	.	H	α-helix	trans	-68.8	-42.2	174.8	-176.8	62.1	0	0	0	111.7	A120 S121 L122 L127 I128 W210	A120-L124 PolarHBondContact O-N 2.94Å; S121-L124 PolarHBondContact O-N 3.39Å; L122-L124 VanDerWaalsContact C-N 3.27Å; L122-L124 PolarHBondContact O-N 3.39Å; L124-L127 PolarHBondContact O-N 3.27Å; L124-I128 WeakPolarHBondContact O-CG1 3.49Å; L124-I128 PolarHBondContact O-N 3.34Å; L124-I128 VanDerWaalsContact O-N 3.09Å; L124-W210 HydrophobicContact CB-CZ2 4.27Å; L124-W210 HydrophobicContact CD2-CH2 3.83Å; L124-W210 HydrophobicContact CD2-CZ2 3.7Å; L124-W210 HydrophobicContact CG-CH2 3.96Å; L124-W210 HydrophobicContact CG-CZ2 3.97Å
125	G	93.4	Very high	91.2	Very high	1 Å²	1	20.7 Å²	20.7	1%	0.01	12%	0.119	C	C	.	.	H	α-helix	trans	-59.7	-48.7	172.7	0	0	0	0	0	111.8	S121 L122 L127 I128 Y129 S168	S121-G125 PolarHBondContact O-N 2.89Å; S121-G125 VanDerWaalsContact O-N 3.11Å; L122-G125 PolarHBondContact O-N 2.92Å; L122-G125 VanDerWaalsContact O-N 3.14Å; G125-L127 VanDerWaalsContact C-N 3.3Å; G125-L127 PolarHBondContact O-N 3.05Å; G125-I128 WeakPolarHBondContact O-CB 3.36Å; G125-I128 PolarHBondContact O-N 3.31Å; G125-I128 VanDerWaalsContact O-N 3.1Å; G125-Y129 PolarHBondContact O-N 3.03Å; G125-S168 PolarHBondContact O-OG 3.32Å; G125-S168 VanDerWaalsContact O-OG 3.04Å
126	D	93.1	Very high	91.3	Very high	0 Å²	0	21.2 Å²	21.2	0%	0	12%	0.121	C	C	.	.	H	α-helix	trans	-59.9	-36.6	177.6	-73.9	-31	0	0	0	112.6	L122 Y129 V130 S362 N365	L122-D126 PolarHBondContact O-N 3.47Å; D126-Y129 PolarHBondContact O-N 2.83Å; D126-V130 WeakPolarHBondContact O-CB 3.44Å; D126-V130 VanDerWaalsContact O-CG2 3.27Å; D126-V130 WeakPolarHBondContact O-CG2 3.45Å; D126-V130 PolarHBondContact O-N 3.48Å; D126-S362 WeakPolarHBondContact OD1-CA 3.41Å; D126-S362 WeakPolarHBondContact OD1-CB 3.47Å; D126-S362 PolarHBondContact OD1-OG 3.33Å; D126-N365 PolarHBondContact OD2-ND2 2.78Å
127	L	93.9	Very high	91	Very high	25 Å²	25	22.3 Å²	22.3	13%	0.131	13%	0.127	C	C	.	.	H	α-helix	trans	-65.7	-44.3	173.1	-79.2	174.7	0	0	0	112.5	M95 N98 L102 A123 L124 G125 Y129 V130 V131	M95-L127 HydrophobicContact SD-CD2 3.92Å; N98-L127 HydrophobicContact CB-CD1 4.31Å; N98-L127 HydrophobicContact CB-CD2 3.79Å; N98-L127 HydrophobicContact CB-CG 3.66Å; L102-L127 HydrophobicContact CD1-CD1 3.5Å; A123-L127 WeakPolarHBondContact O-CG 3.48Å; A123-L127 PolarHBondContact O-N 2.89Å; L124-L127 PolarHBondContact O-N 3.27Å; G125-L127 VanDerWaalsContact C-N 3.3Å; G125-L127 PolarHBondContact O-N 3.05Å; L127-Y129 VanDerWaalsContact C-N 3.26Å; L127-Y129 PolarHBondContact O-N 3.27Å; L127-V130 PolarHBondContact O-N 3.03Å; L127-V131 VanDerWaalsContact O-CB 3.31Å; L127-V131 WeakPolarHBondContact O-CB 3.39Å; L127-V131 WeakPolarHBondContact O-CG2 3.24Å; L127-V131 PolarHBondContact O-N 2.85Å
128	I	91.6	Very high	90.7	Very high	48 Å²	48	23 Å²	23	25%	0.246	13%	0.13	C	C	.	.	H	α-helix	trans	-58.9	-44.1	177.1	-69.1	170	0	0	0	109.8	L124 G125 I132 L164 W210	L124-I128 WeakPolarHBondContact O-CG1 3.49Å; L124-I128 PolarHBondContact O-N 3.34Å; L124-I128 VanDerWaalsContact O-N 3.09Å; G125-I128 WeakPolarHBondContact O-CB 3.36Å; G125-I128 PolarHBondContact O-N 3.31Å; G125-I128 VanDerWaalsContact O-N 3.1Å; I128-I132 HydrophobicContact CG2-CD1 4.16Å; I128-I132 WeakPolarHBondContact O-CB 3.31Å; I128-I132 PolarHBondContact O-N 2.86Å; I128-I132 VanDerWaalsContact O-N 3.13Å; I128-L164 HydrophobicContact CG2-CD2 4.36Å; I128-W210 HydrophobicContact CD1-CH2 3.63Å; I128-W210 HydrophobicContact CD1-CZ3 4.01Å
129	Y	90.8	Very high	90.5	Very high	7 Å²	7	26.4 Å²	26.4	3%	0.027	15%	0.145	C	C	.	.	I	π-helix	trans	-59.9	-53.7	175.7	-171.4	-90	0	0	0	112	G125 D126 L127 V131 I132 D133 L134 Q165 S168 T359	G125-Y129 PolarHBondContact O-N 3.03Å; D126-Y129 PolarHBondContact O-N 2.83Å; L127-Y129 VanDerWaalsContact C-N 3.26Å; L127-Y129 PolarHBondContact O-N 3.27Å; Y129-V131 VanDerWaalsContact C-N 3.34Å; Y129-V131 PolarHBondContact O-N 3.23Å; Y129-I132 PolarHBondContact O-N 3.42Å; Y129-D133 HydrophobicContact CD1-CB 4.36Å; Y129-D133 HydrophobicContact CD2-CB 3.99Å; Y129-D133 HydrophobicContact CE1-CB 4.27Å; Y129-D133 HydrophobicContact CE2-CB 3.94Å; Y129-D133 WeakPolarHBondContact CE2-OD2 3.39Å; Y129-D133 HydrophobicContact CG-CB 4.19Å; Y129-D133 WeakPolarHBondContact O-CA 3.35Å; Y129-D133 WeakPolarHBondContact O-CB 3.27Å; Y129-D133 PolarHBondContact O-N 3.43Å; Y129-D133 PolarHBondContact OH-OD2 2.97Å; Y129-L134 PolarHBondContact O-N 3.1Å; Y129-Q165 HydrophobicContact CE2-CG 3.76Å; Y129-S168 WeakPolarHBondContact CB-OG 3.42Å; Y129-T359 HydrophobicContact CE1-CG2 3.71Å; Y129-T359 WeakPolarHBondContact OH-CG2 3.04Å
130	V	92.4	Very high	90	Very high	0 Å²	0	28.3 Å²	28.3	0%	0	15%	0.153	C	C	.	.	I	π-helix	trans	-65.2	-36.9	-176.5	171.6	0	0	0	0	112.2	F91 M95 D126 L127 L134 P135	F91-V130 HydrophobicContact CD2-CG1 3.69Å; F91-V130 WeakPolarHBondContact CD2-O 3.39Å; F91-V130 HydrophobicContact CE2-CG1 4.23Å; F91-V130 WeakPolarHBondContact CE2-O 3.3Å; F91-V130 HydrophobicContact CG-CG1 4.31Å; M95-V130 HydrophobicContact CG-CG1 4.03Å; M95-V130 HydrophobicContact SD-CG1 4.42Å; D126-V130 WeakPolarHBondContact O-CB 3.44Å; D126-V130 VanDerWaalsContact O-CG2 3.27Å; D126-V130 WeakPolarHBondContact O-CG2 3.45Å; D126-V130 PolarHBondContact O-N 3.48Å; L127-V130 PolarHBondContact O-N 3.03Å; V130-L134 HydrophobicContact CG1-CD2 4.32Å; V130-L134 WeakPolarHBondContact O-CB 3.2Å; V130-P135 WeakPolarHBondContact O-CD 3.46Å
131	V	91.1	Very high	89.4	Confident	73 Å²	73	28 Å²	28	44%	0.442	15%	0.149	S	C	.	.	I	π-helix	trans	-72.8	-37.4	-178.3	171	0	0	0	0	112.2	M95 L127 Y129 P135	M95-V131 HydrophobicContact CE-CG2 4.13Å; M95-V131 HydrophobicContact SD-CG2 3.36Å; M95-V131 WeakPolarHBondContact SD-CG2 3.47Å; L127-V131 VanDerWaalsContact O-CB 3.31Å; L127-V131 WeakPolarHBondContact O-CB 3.39Å; L127-V131 WeakPolarHBondContact O-CG2 3.24Å; L127-V131 PolarHBondContact O-N 2.85Å; Y129-V131 VanDerWaalsContact C-N 3.34Å; Y129-V131 PolarHBondContact O-N 3.23Å; V131-P135 WeakPolarHBondContact O-CD 3.49Å; V131-P135 WeakPolarHBondContact O-CG 3.44Å
132	I	86.9	Confident	88.8	Confident	56 Å²	56	32 Å²	32	29%	0.287	17%	0.169	S	C	.	.	I	π-helix	trans	-106	-48.4	-169.9	-56.8	175.9	0	0	0	111.2	I128 Y129 I136 L164	I128-I132 HydrophobicContact CG2-CD1 4.16Å; I128-I132 WeakPolarHBondContact O-CB 3.31Å; I128-I132 PolarHBondContact O-N 2.86Å; I128-I132 VanDerWaalsContact O-N 3.13Å; Y129-I132 PolarHBondContact O-N 3.42Å; I132-I136 HydrophobicContact CG2-CD1 4.44Å; I132-L164 HydrophobicContact CD1-CD1 3.6Å; I132-L164 HydrophobicContact CG2-CD1 4Å
133	D	85.1	Confident	88.3	Confident	5 Å²	5	33.7 Å²	33.7	3%	0.027	18%	0.183	C	C	.	.	I	π-helix	trans	-72.8	-45.6	-171.6	-165.7	75.6	0	0	0	111.7	Y129 I136 N137 F161 Q165	Y129-D133 HydrophobicContact CD1-CB 4.36Å; Y129-D133 HydrophobicContact CD2-CB 3.99Å; Y129-D133 HydrophobicContact CE1-CB 4.27Å; Y129-D133 HydrophobicContact CE2-CB 3.94Å; Y129-D133 WeakPolarHBondContact CE2-OD2 3.39Å; Y129-D133 HydrophobicContact CG-CB 4.19Å; Y129-D133 WeakPolarHBondContact O-CA 3.35Å; Y129-D133 WeakPolarHBondContact O-CB 3.27Å; Y129-D133 PolarHBondContact O-N 3.43Å; Y129-D133 PolarHBondContact OH-OD2 2.97Å; D133-I136 PolarHBondContact O-N 3.04Å; D133-N137 PolarHBondContact O-N 3.13Å; D133-N137 VanDerWaalsContact O-N 3.1Å; D133-N137 PolarHBondContact O-ND2 3.4Å; D133-N137 VanDerWaalsContact O-ND2 3.13Å; D133-N137 PolarHBondContact OD2-ND2 3.11Å; D133-F161 HydrophobicContact CB-CE2 4.04Å; D133-F161 VanDerWaalsContact O-CE2 3.28Å; D133-F161 WeakPolarHBondContact O-CE2 3.27Å; D133-F161 WeakPolarHBondContact OD1-CE2 3.37Å; D133-F161 WeakPolarHBondContact OD1-CZ 3.39Å; D133-Q165 WeakPolarHBondContact OD1-CB 3.45Å; D133-Q165 WeakPolarHBondContact OD1-CG 3.29Å
134	L	88.3	Confident	87.3	Confident	5 Å²	5	34 Å²	34	3%	0.026	19%	0.187	C	C	.	.	H	α-helix	trans	-65.7	-46.2	-172.3	-166.8	60.3	0	0	0	113.4	S87 I90 F91 Y129 V130 I136 N137 V138 T359	S87-L134 WeakPolarHBondContact O-CD2 3.46Å; I90-L134 HydrophobicContact CB-CD2 4.18Å; I90-L134 HydrophobicContact CG2-CD2 3.87Å; F91-L134 HydrophobicContact CB-CD2 3.69Å; F91-L134 HydrophobicContact CD2-CD2 4.21Å; F91-L134 HydrophobicContact CG-CD2 4.47Å; Y129-L134 PolarHBondContact O-N 3.1Å; V130-L134 HydrophobicContact CG1-CD2 4.32Å; V130-L134 WeakPolarHBondContact O-CB 3.2Å; L134-I136 VanDerWaalsContact C-N 3.34Å; L134-I136 PolarHBondContact O-N 3.09Å; L134-N137 PolarHBondContact O-N 3.32Å; L134-V138 WeakPolarHBondContact O-CG2 3.28Å; L134-V138 PolarHBondContact O-N 3.36Å; L134-T359 HydrophobicContact CD1-CG2 4.22Å
135	P	89.2	Confident	86.6	Confident	57 Å²	57	35.7 Å²	35.7	37%	0.37	19%	0.188	S	C	.	.	H	α-helix	trans	-63.9	-37.1	179.6	-24.1	36.7	0	0	0	113.3	F91 V130 V131 V138 F139	F91-P135 HydrophobicContact CD2-CG 4.48Å; F91-P135 HydrophobicContact CE2-CG 4.13Å; V130-P135 WeakPolarHBondContact O-CD 3.46Å; V131-P135 WeakPolarHBondContact O-CD 3.49Å; V131-P135 WeakPolarHBondContact O-CG 3.44Å; P135-V138 PolarHBondContact O-N 3.01Å; P135-F139 WeakPolarHBondContact O-CB 3.39Å; P135-F139 PolarHBondContact O-N 2.93Å
136	I	86.3	Confident	86.2	Confident	22 Å²	22	35.9 Å²	35.9	11%	0.113	19%	0.189	C	C	.	.	H	α-helix	trans	-69.2	-39.9	179.3	-69.9	169.5	0	0	0	110.5	I132 D133 L134 F139 K140 W146 P147 L157 F161	I132-I136 HydrophobicContact CG2-CD1 4.44Å; D133-I136 PolarHBondContact O-N 3.04Å; L134-I136 VanDerWaalsContact C-N 3.34Å; L134-I136 PolarHBondContact O-N 3.09Å; I136-F139 PolarHBondContact O-N 2.82Å; I136-K140 WeakPolarHBondContact O-CB 3.25Å; I136-K140 PolarHBondContact O-N 3.01Å; I136-W146 HydrophobicContact CG2-CH2 3.89Å; I136-W146 HydrophobicContact CG2-CZ3 4.06Å; I136-P147 HydrophobicContact CG1-CG 4.49Å; I136-P147 HydrophobicContact CG2-CG 4.29Å; I136-L157 HydrophobicContact CD1-CD2 4.48Å; I136-F161 HydrophobicContact CB-CD2 3.8Å; I136-F161 HydrophobicContact CB-CE2 3.52Å; I136-F161 HydrophobicContact CB-CZ 4.36Å; I136-F161 HydrophobicContact CD1-CB 4.38Å; I136-F161 HydrophobicContact CD1-CD2 3.59Å; I136-F161 HydrophobicContact CD1-CE2 4.23Å; I136-F161 HydrophobicContact CD1-CG 4.33Å; I136-F161 HydrophobicContact CG1-CD2 4.27Å; I136-F161 HydrophobicContact CG1-CE2 4.43Å; I136-F161 HydrophobicContact CG2-CD2 3.73Å; I136-F161 HydrophobicContact CG2-CE2 3.53Å; I136-F161 HydrophobicContact CG2-CG 4.23Å; I136-F161 HydrophobicContact CG2-CZ 4.01Å
137	N	83.5	Confident	85.7	Confident	36 Å²	36	36.3 Å²	36.3	19%	0.193	19%	0.191	C	C	.	.	H	α-helix	trans	-62.1	-44.3	174.2	-78.8	-41.8	0	0	0	112.3	D133 L134 K140 L141 F161	D133-N137 PolarHBondContact O-N 3.13Å; D133-N137 VanDerWaalsContact O-N 3.1Å; D133-N137 PolarHBondContact O-ND2 3.4Å; D133-N137 VanDerWaalsContact O-ND2 3.13Å; D133-N137 PolarHBondContact OD2-ND2 3.11Å; L134-N137 PolarHBondContact O-N 3.32Å; N137-K140 PolarHBondContact O-N 3.47Å; N137-L141 PolarHBondContact O-N 3.14Å; N137-F161 WeakPolarHBondContact OD1-CZ 3.5Å
138	V	86.1	Confident	85.2	Confident	23 Å²	23	40.1 Å²	40.1	14%	0.139	21%	0.207	C	C	.	.	H	α-helix	trans	-64.1	-43.4	176.2	174	0	0	0	0	111	T84 L134 P135 K140 L141 L142	T84-V138 HydrophobicContact CG2-CG1 4.13Å; L134-V138 WeakPolarHBondContact O-CG2 3.28Å; L134-V138 PolarHBondContact O-N 3.36Å; P135-V138 PolarHBondContact O-N 3.01Å; V138-K140 VanDerWaalsContact C-N 3.34Å; V138-K140 PolarHBondContact O-N 3.41Å; V138-L141 WeakPolarHBondContact O-CB 3.42Å; V138-L141 PolarHBondContact O-N 2.94Å; V138-L142 HydrophobicContact CG1-CD1 3.75Å; V138-L142 HydrophobicContact CG1-CG 4.25Å; V138-L142 WeakPolarHBondContact O-CG 3.36Å; V138-L142 PolarHBondContact O-N 3.25Å
139	F	86.4	Confident	84.6	Confident	73 Å²	73	38.9 Å²	38.9	32%	0.32	20%	0.201	S	C	.	.	H	α-helix	trans	-59	-46.6	175.6	-178.4	-86.3	0	0	0	111.3	P135 I136 L141 L142 A143 R145 P147	P135-F139 WeakPolarHBondContact O-CB 3.39Å; P135-F139 PolarHBondContact O-N 2.93Å; I136-F139 PolarHBondContact O-N 2.82Å; F139-L141 VanDerWaalsContact C-N 3.29Å; F139-L141 PolarHBondContact O-N 3.24Å; F139-L142 PolarHBondContact O-N 3.44Å; F139-A143 HydrophobicContact CD1-CB 4.12Å; F139-A143 HydrophobicContact CD2-CB 4.39Å; F139-A143 HydrophobicContact CE1-CB 3.75Å; F139-A143 HydrophobicContact CE2-CB 4.06Å; F139-A143 HydrophobicContact CG-CB 4.43Å; F139-A143 HydrophobicContact CZ-CB 3.72Å; F139-A143 VanDerWaalsContact O-CB 3.26Å; F139-A143 WeakPolarHBondContact O-CB 3.35Å; F139-A143 PolarHBondContact O-N 2.78Å; F139-R145 HydrophobicContact CE1-CG 4.08Å; F139-R145 WeakPolarHBondContact CE1-O 3.38Å; F139-R145 HydrophobicContact CZ-CG 4.42Å; F139-P147 HydrophobicContact CD1-CB 3.79Å; F139-P147 HydrophobicContact CD1-CG 4.17Å; F139-P147 VanDerWaalsContact CE1-CA 3.48Å; F139-P147 HydrophobicContact CE1-CB 3.74Å; F139-P147 HydrophobicContact CE1-CG 4.46Å; F139-P147 HydrophobicContact CG-CB 4.37Å; F139-P147 HydrophobicContact CZ-CB 4.27Å
140	K	82.5	Confident	84	Confident	56 Å²	56	44.3 Å²	44.3	24%	0.243	23%	0.226	C	C	.	.	H	α-helix	trans	-59.9	-40.2	178.1	-172	-177.7	-178.9	-173.7	0	111.7	I136 N137 V138 G144	I136-K140 WeakPolarHBondContact O-CB 3.25Å; I136-K140 PolarHBondContact O-N 3.01Å; N137-K140 PolarHBondContact O-N 3.47Å; V138-K140 VanDerWaalsContact C-N 3.34Å; V138-K140 PolarHBondContact O-N 3.41Å; K140-G144 WeakPolarHBondContact O-CA 3.47Å; K140-G144 PolarHBondContact O-N 3.33Å; K140-G144 VanDerWaalsContact O-N 3.13Å
141	L	80.6	Confident	83.6	Confident	13 Å²	13	48.5 Å²	48.5	7%	0.068	25%	0.249	C	C	.	.	H	α-helix	trans	-66.1	-43.7	177.2	178.5	69.1	0	0	0	112.8	K80 T83 N137 V138 F139 Y352	K80-L141 HydrophobicContact CG-CD1 4.33Å; K80-L141 HydrophobicContact CG-CG 4.46Å; T83-L141 HydrophobicContact CG2-CD2 3.38Å; N137-L141 PolarHBondContact O-N 3.14Å; V138-L141 WeakPolarHBondContact O-CB 3.42Å; V138-L141 PolarHBondContact O-N 2.94Å; F139-L141 VanDerWaalsContact C-N 3.29Å; F139-L141 PolarHBondContact O-N 3.24Å; L141-Y352 HydrophobicContact CD1-CE1 3.83Å
142	L	82.5	Confident	83.4	Confident	92 Å²	92	52 Å²	52	48%	0.482	27%	0.265	S	S	.	.	H	α-helix	trans	-81	-48.8	-174.9	-69.1	177.9	0	0	0	112.7	T84 V138 F139	T84-L142 HydrophobicContact CG2-CD1 4.16Å; T84-L142 WeakPolarHBondContact OG1-CD2 3.38Å; V138-L142 HydrophobicContact CG1-CD1 3.75Å; V138-L142 HydrophobicContact CG1-CG 4.25Å; V138-L142 WeakPolarHBondContact O-CG 3.36Å; V138-L142 PolarHBondContact O-N 3.25Å; F139-L142 PolarHBondContact O-N 3.44Å
143	A	80.8	Confident	83.4	Confident	38 Å²	38	54.4 Å²	54.4	31%	0.314	27%	0.273	S	S	.	.	H	α-helix	trans	-84.7	-14.6	-174.6	0	0	0	0	0	112.8	F139 R145	F139-A143 HydrophobicContact CD1-CB 4.12Å; F139-A143 HydrophobicContact CD2-CB 4.39Å; F139-A143 HydrophobicContact CE1-CB 3.75Å; F139-A143 HydrophobicContact CE2-CB 4.06Å; F139-A143 HydrophobicContact CG-CB 4.43Å; F139-A143 HydrophobicContact CZ-CB 3.72Å; F139-A143 VanDerWaalsContact O-CB 3.26Å; F139-A143 WeakPolarHBondContact O-CB 3.35Å; F139-A143 PolarHBondContact O-N 2.78Å; A143-R145 HydrophobicContact CB-CG 3.96Å; A143-R145 PolarHBondContact O-N 2.92Å; A143-R145 VanDerWaalsContact O-N 3.11Å
144	G	74.3	Confident	83.5	Confident	9 Å²	9	54.2 Å²	54.2	9%	0.093	27%	0.273	C	S	.	.	S	Bend	trans	57.9	27	-177.6	0	0	0	0	0	112.7	F47 K140	F47-G144 WeakPolarHBondContact CB-O 3.4Å; K140-G144 WeakPolarHBondContact O-CA 3.47Å; K140-G144 PolarHBondContact O-N 3.33Å; K140-G144 VanDerWaalsContact O-N 3.13Å
145	R	80.3	Confident	83.5	Confident	110 Å²	110	56.3 Å²	56.3	42%	0.415	29%	0.285	S	S	.	.	S	Bend	trans	-149.9	162.5	179.2	65.8	-177.9	178.3	128.1	-9.4	110.9	F139 A143 D149 H150	F139-R145 HydrophobicContact CE1-CG 4.08Å; F139-R145 WeakPolarHBondContact CE1-O 3.38Å; F139-R145 HydrophobicContact CZ-CG 4.42Å; A143-R145 HydrophobicContact CB-CG 3.96Å; A143-R145 PolarHBondContact O-N 2.92Å; A143-R145 VanDerWaalsContact O-N 3.11Å; R145-D149 IonicContact NH1-OD1 2.89Å; R145-D149 PolarHBondContact NH1-OD1 3.35Å; R145-H150 PolarHBondContact NH1-CE1 3.36Å; R145-H150 PolarHBondContact NH1-NE2 2.92Å
146	W	83.9	Confident	83.5	Confident	6 Å²	6	59 Å²	59	2%	0.023	29%	0.292	C	S	.	.			trans	-75.5	137.4	173.6	-171.8	-100.5	0	0	0	110.2	I136 F148 D149 G154 L157 C158 F161 M226 C239	I136-W146 HydrophobicContact CG2-CH2 3.89Å; I136-W146 HydrophobicContact CG2-CZ3 4.06Å; W146-F148 PolarHBondContact O-N 3.34Å; W146-D149 HydrophobicContact CB-CB 4.31Å; W146-G154 PolarHBondContact NE1-O 3.39Å; W146-L157 HydrophobicContact CZ2-CB 4.08Å; W146-C158 VanDerWaalsContact CZ2-CA 3.42Å; W146-C158 HydrophobicContact CZ2-CB 4.06Å; W146-F161 HydrophobicContact CH2-CB 4.17Å; W146-F161 AromaticContact CH2-CD1 3.94Å; W146-F161 HydrophobicContact CH2-CD1 3.94Å; W146-F161 HydrophobicContact CH2-CG 4.12Å; W146-M226 HydrophobicContact CB-CE 4.01Å; W146-M226 HydrophobicContact CB-SD 4.41Å; W146-M226 VanDerWaalsContact CD1-SD 3.58Å; W146-M226 HydrophobicContact CD2-SD 4.48Å; W146-M226 HydrophobicContact CG-CE 4.05Å; W146-M226 HydrophobicContact CG-SD 3.89Å; W146-C239 HydrophobicContact CD2-CB 3.49Å; W146-C239 VanDerWaalsContact CD2-CB 3.49Å; W146-C239 HydrophobicContact CE3-CB 3.45Å; W146-C239 VanDerWaalsContact CE3-CB 3.45Å; W146-C239 HydrophobicContact CG-CB 4.12Å; W146-C239 HydrophobicContact CH2-CB 4.12Å; W146-C239 HydrophobicContact CZ2-CB 4.17Å; W146-C239 HydrophobicContact CZ3-CB 3.76Å
147	P	83.8	Confident	83.7	Confident	8 Å²	8	59 Å²	59	5%	0.052	29%	0.291	C	S	.	.	T	Hydrogen-bonded Turn	trans	-64.5	135.4	178.6	26.4	-34.6	0	0	0	111.1	I136 F139 D149	I136-P147 HydrophobicContact CG1-CG 4.49Å; I136-P147 HydrophobicContact CG2-CG 4.29Å; F139-P147 HydrophobicContact CD1-CB 3.79Å; F139-P147 HydrophobicContact CD1-CG 4.17Å; F139-P147 VanDerWaalsContact CE1-CA 3.48Å; F139-P147 HydrophobicContact CE1-CB 3.74Å; F139-P147 HydrophobicContact CE1-CG 4.46Å; F139-P147 HydrophobicContact CG-CB 4.37Å; F139-P147 HydrophobicContact CZ-CB 4.27Å; P147-D149 PolarHBondContact O-N 2.86Å
148	F	83.4	Confident	84	Confident	105 Å²	105	57.2 Å²	57.2	46%	0.461	28%	0.282	S	S	.	.	T	Hydrogen-bonded Turn	trans	56.2	34.6	178.1	-47.2	-76.3	0	0	0	114	W146 H150 N151 F153 G154 L157	W146-F148 PolarHBondContact O-N 3.34Å; F148-H150 PolarHBondContact O-N 3.45Å; F148-N151 PolarHBondContact O-N 2.86Å; F148-F153 HydrophobicContact CB-CD1 4.23Å; F148-F153 AromaticContact CD2-CD1 3.67Å; F148-F153 HydrophobicContact CD2-CD1 3.67Å; F148-F153 AromaticContact CD2-CE1 3.84Å; F148-F153 HydrophobicContact CD2-CE1 3.84Å; F148-F153 HydrophobicContact CE2-CD1 4.18Å; F148-F153 AromaticContact CE2-CE1 3.93Å; F148-F153 HydrophobicContact CE2-CE1 3.93Å; F148-F153 AromaticContact CG-CD1 3.95Å; F148-F153 HydrophobicContact CG-CD1 3.95Å; F148-G154 WeakPolarHBondContact O-CA 3.31Å; F148-G154 PolarHBondContact O-N 3.43Å; F148-L157 HydrophobicContact CD2-CD1 3.92Å; F148-L157 HydrophobicContact CE2-CD1 4.46Å
149	D	79.3	Confident	84.3	Confident	23 Å²	23	59.4 Å²	59.4	12%	0.123	29%	0.29	C	S	.	.	T	Hydrogen-bonded Turn	trans	-58.6	-18.8	-178	61.1	-55.5	0	0	0	114.7	R145 W146 P147 M226 R237	R145-D149 IonicContact NH1-OD1 2.89Å; R145-D149 PolarHBondContact NH1-OD1 3.35Å; W146-D149 HydrophobicContact CB-CB 4.31Å; P147-D149 PolarHBondContact O-N 2.86Å; D149-M226 HydrophobicContact CB-CE 3.87Å; D149-R237 HydrophobicContact CB-CB 4.47Å; D149-R237 PolarHBondContact O-NH1 3.25Å
150	H	78.1	Confident	84.5	Confident	121 Å²	121	58.3 Å²	58.3	56%	0.56	29%	0.287	S	S	*	.	T	Hydrogen-bonded Turn	trans	-80.5	-23.9	176.4	-12.5	-60.9	0	0	0	113.3	R145 F148	R145-H150 PolarHBondContact NH1-CE1 3.36Å; R145-H150 PolarHBondContact NH1-NE2 2.92Å; F148-H150 PolarHBondContact O-N 3.45Å
151	N	84.3	Confident	84.8	Confident	88 Å²	88	56.3 Å²	56.3	47%	0.471	28%	0.278	S	S	.	.	S	Bend	trans	-108.9	156.4	-169.1	-64.1	-11.1	0	0	0	111.2	F148 F153 G154	F148-N151 PolarHBondContact O-N 2.86Å; N151-F153 HydrophobicContact CB-CB 4.42Å; N151-F153 PolarHBondContact O-N 3.02Å; N151-F153 VanDerWaalsContact O-N 3.13Å; N151-G154 PolarHBondContact O-N 2.87Å
152	D	85.9	Confident	85.3	Confident	147 Å²	147	55.9 Å²	55.9	79%	0.786	28%	0.276	S	S	*	.	H	α-helix	trans	-58.9	-26.7	173.3	-65.6	-34.4	0	0	0	112.5	G154 V155 F156	D152-G154 VanDerWaalsContact C-N 3.29Å; D152-G154 PolarHBondContact O-N 2.75Å; D152-V155 WeakPolarHBondContact O-CB 3.34Å; D152-V155 PolarHBondContact O-N 2.87Å; D152-F156 PolarHBondContact O-N 3.35Å
153	F	87.3	Confident	85.8	Confident	106 Å²	106	53.4 Å²	53.4	47%	0.465	26%	0.262	S	S	.	.	H	α-helix	trans	-60	-36.3	172.5	-171.8	-114.3	0	0	0	112.7	F148 N151 V155 F156 L157	F148-F153 HydrophobicContact CB-CD1 4.23Å; F148-F153 AromaticContact CD2-CD1 3.67Å; F148-F153 HydrophobicContact CD2-CD1 3.67Å; F148-F153 AromaticContact CD2-CE1 3.84Å; F148-F153 HydrophobicContact CD2-CE1 3.84Å; F148-F153 HydrophobicContact CE2-CD1 4.18Å; F148-F153 AromaticContact CE2-CE1 3.93Å; F148-F153 HydrophobicContact CE2-CE1 3.93Å; F148-F153 AromaticContact CG-CD1 3.95Å; F148-F153 HydrophobicContact CG-CD1 3.95Å; N151-F153 HydrophobicContact CB-CB 4.42Å; N151-F153 PolarHBondContact O-N 3.02Å; N151-F153 VanDerWaalsContact O-N 3.13Å; F153-V155 VanDerWaalsContact C-N 3.35Å; F153-F156 HydrophobicContact CD2-CD1 4.31Å; F153-F156 HydrophobicContact CE2-CD1 4.24Å; F153-F156 PolarHBondContact O-N 3.35Å; F153-L157 HydrophobicContact CD1-CD1 3.82Å; F153-L157 HydrophobicContact CD1-CG 4.26Å; F153-L157 HydrophobicContact CE1-CD1 3.49Å; F153-L157 VanDerWaalsContact CE1-CD1 3.49Å; F153-L157 HydrophobicContact CE1-CD2 4.37Å; F153-L157 HydrophobicContact CE1-CG 3.97Å; F153-L157 HydrophobicContact CE2-CG 4.49Å; F153-L157 HydrophobicContact CZ-CD1 4.05Å; F153-L157 HydrophobicContact CZ-CD2 4.08Å; F153-L157 HydrophobicContact CZ-CG 4.08Å; F153-L157 WeakPolarHBondContact O-CB 3.42Å; F153-L157 WeakPolarHBondContact O-CG 3.43Å; F153-L157 PolarHBondContact O-N 3.49Å
154	G	87	Confident	86.3	Confident	1 Å²	1	53 Å²	53	1%	0.01	25%	0.254	C	S	.	.	H	α-helix	trans	-66.1	-36.8	175.7	0	0	0	0	0	112.6	W146 F148 N151 D152 L157 C158	W146-G154 PolarHBondContact NE1-O 3.39Å; F148-G154 WeakPolarHBondContact O-CA 3.31Å; F148-G154 PolarHBondContact O-N 3.43Å; N151-G154 PolarHBondContact O-N 2.87Å; D152-G154 VanDerWaalsContact C-N 3.29Å; D152-G154 PolarHBondContact O-N 2.75Å; G154-L157 PolarHBondContact O-N 3.3Å; G154-C158 WeakPolarHBondContact O-CB 3.37Å; G154-C158 PolarHBondContact O-N 3.46Å
155	V	87.8	Confident	87.1	Confident	48 Å²	48	54.1 Å²	54.1	29%	0.291	26%	0.257	S	S	.	.	H	α-helix	trans	-66.7	-43.9	174.7	-178.1	0	0	0	0	110.7	D152 F153 C158 K159 M226	D152-V155 WeakPolarHBondContact O-CB 3.34Å; D152-V155 PolarHBondContact O-N 2.87Å; F153-V155 VanDerWaalsContact C-N 3.35Å; V155-C158 WeakPolarHBondContact O-CB 3.41Å; V155-C158 PolarHBondContact O-N 2.73Å; V155-K159 PolarHBondContact O-N 3.08Å; V155-M226 HydrophobicContact CB-CG 4.42Å; V155-M226 HydrophobicContact CG2-CB 4.37Å; V155-M226 HydrophobicContact CG2-CG 3.93Å
156	F	90.5	Very high	87.6	Confident	115 Å²	115	49.4 Å²	49.4	50%	0.504	24%	0.239	S	C	.	.	H	α-helix	trans	-58.5	-48.8	173.9	171.8	-104	0	0	0	111.6	D152 F153 C158 K159 L160	D152-F156 PolarHBondContact O-N 3.35Å; F153-F156 HydrophobicContact CD2-CD1 4.31Å; F153-F156 HydrophobicContact CE2-CD1 4.24Å; F153-F156 PolarHBondContact O-N 3.35Å; F156-C158 VanDerWaalsContact C-N 3.29Å; F156-C158 PolarHBondContact O-N 3.32Å; F156-K159 PolarHBondContact O-N 3.47Å; F156-K159 VanDerWaalsContact O-N 3.16Å; F156-L160 HydrophobicContact CD1-CD2 4.45Å; F156-L160 HydrophobicContact CE1-CB 4.38Å; F156-L160 HydrophobicContact CE1-CD2 3.54Å; F156-L160 HydrophobicContact CZ-CB 4.35Å; F156-L160 HydrophobicContact CZ-CD2 3.69Å; F156-L160 HydrophobicContact CZ-CG 4.4Å; F156-L160 WeakPolarHBondContact O-CB 3.12Å; F156-L160 PolarHBondContact O-N 3.33Å
157	L	89.3	Confident	88.1	Confident	20 Å²	20	49.2 Å²	49.2	11%	0.105	24%	0.239	C	C	.	.	H	α-helix	trans	-60	-38.6	176.2	-73.2	178.8	0	0	0	112.2	I136 W146 F148 F153 G154 K159 L160 F161	I136-L157 HydrophobicContact CD1-CD2 4.48Å; W146-L157 HydrophobicContact CZ2-CB 4.08Å; F148-L157 HydrophobicContact CD2-CD1 3.92Å; F148-L157 HydrophobicContact CE2-CD1 4.46Å; F153-L157 HydrophobicContact CD1-CD1 3.82Å; F153-L157 HydrophobicContact CD1-CG 4.26Å; F153-L157 HydrophobicContact CE1-CD1 3.49Å; F153-L157 VanDerWaalsContact CE1-CD1 3.49Å; F153-L157 HydrophobicContact CE1-CD2 4.37Å; F153-L157 HydrophobicContact CE1-CG 3.97Å; F153-L157 HydrophobicContact CE2-CG 4.49Å; F153-L157 HydrophobicContact CZ-CD1 4.05Å; F153-L157 HydrophobicContact CZ-CD2 4.08Å; F153-L157 HydrophobicContact CZ-CG 4.08Å; F153-L157 WeakPolarHBondContact O-CB 3.42Å; F153-L157 WeakPolarHBondContact O-CG 3.43Å; F153-L157 PolarHBondContact O-N 3.49Å; G154-L157 PolarHBondContact O-N 3.3Å; L157-K159 PolarHBondContact O-N 3.13Å; L157-L160 PolarHBondContact O-N 3.33Å; L157-F161 WeakPolarHBondContact O-CB 3.41Å; L157-F161 PolarHBondContact O-N 3.24Å
158	C	90.6	Very high	88.5	Confident	0 Å²	0	49 Å²	49	0%	0	24%	0.237	C	C	.	.	H	α-helix	trans	-60.1	-29.8	179	176.1	0	0	0	0	112.8	W146 G154 V155 F156 P162 F224 M226 C239	W146-C158 VanDerWaalsContact CZ2-CA 3.42Å; W146-C158 HydrophobicContact CZ2-CB 4.06Å; G154-C158 WeakPolarHBondContact O-CB 3.37Å; G154-C158 PolarHBondContact O-N 3.46Å; V155-C158 WeakPolarHBondContact O-CB 3.41Å; V155-C158 PolarHBondContact O-N 2.73Å; F156-C158 VanDerWaalsContact C-N 3.29Å; F156-C158 PolarHBondContact O-N 3.32Å; C158-P162 WeakPolarHBondContact O-CD 3.3Å; C158-P162 VanDerWaalsContact O-CG 3.3Å; C158-P162 WeakPolarHBondContact O-CG 3.34Å; C158-F224 WeakPolarHBondContact O-CB 3.44Å; C158-M226 HydrophobicContact CB-CG 4.02Å; C158-M226 HydrophobicContact CB-SD 3.85Å; C158-C239 WeakPolarHBondContact CA-SG 3.4Å; C158-C239 HydrophobicContact CB-CB 3.73Å; C158-C239 WeakPolarHBondContact CB-SG 3.36Å; C158-C239 PolarHBondContact O-SG 2.97Å; C158-C239 WeakPolarHBondContact SG-CA 3.41Å; C158-C239 WeakPolarHBondContact SG-CB 3.42Å; C158-C239 CovalentContact SG-SG 2.03Å; C158-C239 PolarHBondContact SG-SG 2.74Å
159	K	91.6	Very high	88.9	Confident	69 Å²	69	44.2 Å²	44.2	30%	0.3	22%	0.217	S	C	.	.	H	α-helix	trans	-88.1	-43.2	174.9	-66.5	-173.9	166.4	-59.9	0	112.6	V155 F156 L157 F163 A221 I222 F224	V155-K159 PolarHBondContact O-N 3.08Å; F156-K159 PolarHBondContact O-N 3.47Å; F156-K159 VanDerWaalsContact O-N 3.16Å; L157-K159 PolarHBondContact O-N 3.13Å; K159-F163 WeakPolarHBondContact O-CB 3.25Å; K159-A221 WeakPolarHBondContact CD-O 3.38Å; K159-A221 WeakPolarHBondContact CG-O 3.29Å; K159-A221 PolarHBondContact NZ-O 3.31Å; K159-I222 PolarHBondContact NZ-O 3.46Å; K159-F224 WeakPolarHBondContact CG-O 3.28Å; K159-F224 PolarHBondContact NZ-O 2.95Å
160	L	90.8	Very high	89.6	Confident	49 Å²	49	43.1 Å²	43.1	26%	0.257	21%	0.211	S	C	.	.	H	α-helix	trans	-66.9	-41.2	-175.8	-179.2	66.3	0	0	0	112	F156 L157 F163 L164	F156-L160 HydrophobicContact CD1-CD2 4.45Å; F156-L160 HydrophobicContact CE1-CB 4.38Å; F156-L160 HydrophobicContact CE1-CD2 3.54Å; F156-L160 HydrophobicContact CZ-CB 4.35Å; F156-L160 HydrophobicContact CZ-CD2 3.69Å; F156-L160 HydrophobicContact CZ-CG 4.4Å; F156-L160 WeakPolarHBondContact O-CB 3.12Å; F156-L160 PolarHBondContact O-N 3.33Å; L157-L160 PolarHBondContact O-N 3.33Å; L160-F163 HydrophobicContact CD1-CD1 4.39Å; L160-F163 WeakPolarHBondContact O-CB 3.32Å; L160-F163 PolarHBondContact O-N 2.67Å; L160-L164 HydrophobicContact CD1-CD1 3.76Å; L160-L164 HydrophobicContact CD1-CD2 4.4Å; L160-L164 HydrophobicContact CD1-CG 3.84Å; L160-L164 HydrophobicContact CD2-CD1 4.08Å; L160-L164 HydrophobicContact CG-CD1 3.64Å; L160-L164 HydrophobicContact CG-CG 4.08Å; L160-L164 WeakPolarHBondContact O-CB 3.32Å; L160-L164 WeakPolarHBondContact O-CG 3.3Å; L160-L164 PolarHBondContact O-N 2.93Å
161	F	89.1	Confident	90.4	Very high	14 Å²	14	37.5 Å²	37.5	6%	0.061	19%	0.185	C	C	.	.	H	α-helix	trans	-65.5	-55.4	-172.9	168	-88.2	0	0	0	113	D133 I136 N137 W146 L157 F163 L164 Q165	D133-F161 HydrophobicContact CB-CE2 4.04Å; D133-F161 VanDerWaalsContact O-CE2 3.28Å; D133-F161 WeakPolarHBondContact O-CE2 3.27Å; D133-F161 WeakPolarHBondContact OD1-CE2 3.37Å; D133-F161 WeakPolarHBondContact OD1-CZ 3.39Å; I136-F161 HydrophobicContact CB-CD2 3.8Å; I136-F161 HydrophobicContact CB-CE2 3.52Å; I136-F161 HydrophobicContact CB-CZ 4.36Å; I136-F161 HydrophobicContact CD1-CB 4.38Å; I136-F161 HydrophobicContact CD1-CD2 3.59Å; I136-F161 HydrophobicContact CD1-CE2 4.23Å; I136-F161 HydrophobicContact CD1-CG 4.33Å; I136-F161 HydrophobicContact CG1-CD2 4.27Å; I136-F161 HydrophobicContact CG1-CE2 4.43Å; I136-F161 HydrophobicContact CG2-CD2 3.73Å; I136-F161 HydrophobicContact CG2-CE2 3.53Å; I136-F161 HydrophobicContact CG2-CG 4.23Å; I136-F161 HydrophobicContact CG2-CZ 4.01Å; N137-F161 WeakPolarHBondContact OD1-CZ 3.5Å; W146-F161 HydrophobicContact CH2-CB 4.17Å; W146-F161 AromaticContact CH2-CD1 3.94Å; W146-F161 HydrophobicContact CH2-CD1 3.94Å; W146-F161 HydrophobicContact CH2-CG 4.12Å; L157-F161 WeakPolarHBondContact O-CB 3.41Å; L157-F161 PolarHBondContact O-N 3.24Å; F161-F163 PolarHBondContact O-N 2.99Å; F161-L164 PolarHBondContact O-N 3.25Å; F161-Q165 WeakPolarHBondContact O-CB 3.34Å; F161-Q165 PolarHBondContact O-N 2.86Å
162	P	90.4	Very high	90.8	Very high	4 Å²	4	33.4 Å²	33.4	3%	0.026	16%	0.163	C	C	.	.	H	α-helix	trans	-61.1	-33.7	177.5	-22	35	0	0	0	112.2	C158 K166 E220 F224	C158-P162 WeakPolarHBondContact O-CD 3.3Å; C158-P162 VanDerWaalsContact O-CG 3.3Å; C158-P162 WeakPolarHBondContact O-CG 3.34Å; P162-K166 WeakPolarHBondContact O-CG 3.5Å; P162-K166 PolarHBondContact O-N 3.29Å; P162-E220 HydrophobicContact CB-CB 4.11Å; P162-F224 HydrophobicContact CB-CD1 4.22Å; P162-F224 HydrophobicContact CB-CD2 3.97Å; P162-F224 HydrophobicContact CB-CE1 4.35Å; P162-F224 HydrophobicContact CB-CE2 4.15Å; P162-F224 HydrophobicContact CB-CG 4.01Å; P162-F224 HydrophobicContact CB-CZ 4.31Å; P162-F224 HydrophobicContact CG-CB 4.05Å; P162-F224 HydrophobicContact CG-CD1 3.5Å; P162-F224 HydrophobicContact CG-CD2 4.07Å; P162-F224 HydrophobicContact CG-CE1 3.89Å; P162-F224 HydrophobicContact CG-CE2 4.45Å; P162-F224 HydrophobicContact CG-CG 3.58Å; P162-F224 HydrophobicContact CG-CZ 4.35Å
163	F	93.7	Very high	91.2	Very high	40 Å²	40	26.4 Å²	26.4	18%	0.175	13%	0.126	C	C	.	.	H	α-helix	trans	-62.5	-52.5	174.3	168.5	-98.3	0	0	0	112.3	K159 L160 F161 Q165 K166 S167 F214 A217 A221	K159-F163 WeakPolarHBondContact O-CB 3.25Å; L160-F163 HydrophobicContact CD1-CD1 4.39Å; L160-F163 WeakPolarHBondContact O-CB 3.32Å; L160-F163 PolarHBondContact O-N 2.67Å; F161-F163 PolarHBondContact O-N 2.99Å; F163-Q165 VanDerWaalsContact C-N 3.32Å; F163-Q165 PolarHBondContact O-N 3.01Å; F163-K166 PolarHBondContact O-N 3.47Å; F163-S167 WeakPolarHBondContact O-CB 3.39Å; F163-S167 PolarHBondContact O-N 3.35Å; F163-S167 PolarHBondContact O-OG 3.42Å; F163-F214 HydrophobicContact CE2-CB 4.5Å; F163-F214 WeakPolarHBondContact CE2-O 3.12Å; F163-F214 HydrophobicContact CZ-CB 4.14Å; F163-F214 HydrophobicContact CZ-CD1 4.07Å; F163-F214 HydrophobicContact CZ-CG 4.18Å; F163-A217 HydrophobicContact CD2-CB 3.68Å; F163-A217 HydrophobicContact CE2-CB 3.88Å; F163-A217 WeakPolarHBondContact O-CB 3.28Å; F163-A221 HydrophobicContact CB-CB 4.04Å; F163-A221 HydrophobicContact CD2-CB 4.22Å; F163-A221 HydrophobicContact CG-CB 4.36Å
164	L	92	Very high	91.6	Very high	30 Å²	30	22.2 Å²	22.2	16%	0.157	11%	0.108	C	C	.	.	H	α-helix	trans	-65.7	-37.9	178.8	-72.4	177.2	0	0	0	111.4	I128 I132 L160 F161 S167 S168	I128-L164 HydrophobicContact CG2-CD2 4.36Å; I132-L164 HydrophobicContact CD1-CD1 3.6Å; I132-L164 HydrophobicContact CG2-CD1 4Å; L160-L164 HydrophobicContact CD1-CD1 3.76Å; L160-L164 HydrophobicContact CD1-CD2 4.4Å; L160-L164 HydrophobicContact CD1-CG 3.84Å; L160-L164 HydrophobicContact CD2-CD1 4.08Å; L160-L164 HydrophobicContact CG-CD1 3.64Å; L160-L164 HydrophobicContact CG-CG 4.08Å; L160-L164 WeakPolarHBondContact O-CB 3.32Å; L160-L164 WeakPolarHBondContact O-CG 3.3Å; L160-L164 PolarHBondContact O-N 2.93Å; F161-L164 PolarHBondContact O-N 3.25Å; L164-S167 PolarHBondContact O-N 2.94Å; L164-S168 WeakPolarHBondContact O-CB 3.31Å; L164-S168 PolarHBondContact O-N 2.85Å
165	Q	89.9	Confident	91.9	Very high	32 Å²	32	22.1 Å²	22.1	15%	0.15	11%	0.108	C	C	.	.	H	α-helix	trans	-54.8	-59.2	174.3	-166.3	-176.6	16.7	0	0	109.7	Y129 D133 F161 F163 S167 S168 V169	Y129-Q165 HydrophobicContact CE2-CG 3.76Å; D133-Q165 WeakPolarHBondContact OD1-CB 3.45Å; D133-Q165 WeakPolarHBondContact OD1-CG 3.29Å; F161-Q165 WeakPolarHBondContact O-CB 3.34Å; F161-Q165 PolarHBondContact O-N 2.86Å; F163-Q165 VanDerWaalsContact C-N 3.32Å; F163-Q165 PolarHBondContact O-N 3.01Å; Q165-S167 PolarHBondContact O-N 3.45Å; Q165-S168 PolarHBondContact O-N 3.01Å; Q165-V169 WeakPolarHBondContact O-CG2 3.49Å; Q165-V169 PolarHBondContact O-N 3.46Å
166	K	91.3	Very high	92	Very high	12 Å²	12	20 Å²	20	5%	0.052	9%	0.094	C	C	.	.	H	α-helix	trans	-66.3	-37.3	-179.3	-66.9	-45.4	-174.6	177.6	0	113.7	P162 F163 S168 V169 G170 A217 E220 L259	P162-K166 WeakPolarHBondContact O-CG 3.5Å; P162-K166 PolarHBondContact O-N 3.29Å; F163-K166 PolarHBondContact O-N 3.47Å; K166-S168 VanDerWaalsContact C-N 3.32Å; K166-S168 PolarHBondContact O-N 3.44Å; K166-V169 PolarHBondContact O-N 3.45Å; K166-G170 PolarHBondContact O-N 3.44Å; K166-A217 HydrophobicContact CB-CB 3.94Å; K166-E220 HydrophobicContact CB-CG 4.18Å; K166-E220 VanDerWaalsContact CE-OE1 3.32Å; K166-E220 WeakPolarHBondContact CE-OE1 3.42Å; K166-E220 HydrophobicContact CG-CG 3.59Å; K166-E220 WeakPolarHBondContact CG-OE1 3.49Å; K166-L259 HydrophobicContact CD-CD2 4.2Å
167	S	94.3	Very high	92.2	Very high	1 Å²	1	14.9 Å²	14.9	1%	0.007	7%	0.073	C	C	.	.	H	α-helix	trans	-57.5	-46.1	174	-66.9	0	0	0	0	111.4	F163 L164 Q165 V169 G170 I171 S213 F214 A217	F163-S167 WeakPolarHBondContact O-CB 3.39Å; F163-S167 PolarHBondContact O-N 3.35Å; F163-S167 PolarHBondContact O-OG 3.42Å; L164-S167 PolarHBondContact O-N 2.94Å; Q165-S167 PolarHBondContact O-N 3.45Å; S167-V169 PolarHBondContact O-N 3.23Å; S167-G170 WeakPolarHBondContact O-CA 3.47Å; S167-G170 PolarHBondContact O-N 3.12Å; S167-G170 VanDerWaalsContact O-N 3.16Å; S167-I171 WeakPolarHBondContact O-CG1 3.39Å; S167-I171 PolarHBondContact O-N 3.39Å; S167-S213 WeakPolarHBondContact O-CB 3.37Å; S167-F214 WeakPolarHBondContact OG-CD1 3.44Å; S167-A217 WeakPolarHBondContact OG-CB 3.5Å
168	S	92.6	Very high	92.3	Very high	3 Å²	3	14.2 Å²	14.2	2%	0.021	7%	0.07	C	C	.	.	H	α-helix	trans	-63.7	-43.4	179.2	-171.1	0	0	0	0	111.9	G125 Y129 L164 Q165 K166 G170 I171 T172	G125-S168 PolarHBondContact O-OG 3.32Å; G125-S168 VanDerWaalsContact O-OG 3.04Å; Y129-S168 WeakPolarHBondContact CB-OG 3.42Å; L164-S168 WeakPolarHBondContact O-CB 3.31Å; L164-S168 PolarHBondContact O-N 2.85Å; Q165-S168 PolarHBondContact O-N 3.01Å; K166-S168 VanDerWaalsContact C-N 3.32Å; K166-S168 PolarHBondContact O-N 3.44Å; S168-G170 PolarHBondContact O-N 2.87Å; S168-I171 PolarHBondContact O-N 2.95Å; S168-T172 PolarHBondContact O-N 3.31Å; S168-T172 PolarHBondContact O-OG1 2.85Å
169	V	91.2	Very high	92.3	Very high	5 Å²	5	14.4 Å²	14.4	3%	0.03	7%	0.071	C	C	.	.	H	α-helix	trans	-59.9	-38.7	175.6	-171.5	0	0	0	0	110.6	Q165 K166 S167 T172 V173 Y263 W319	Q165-V169 WeakPolarHBondContact O-CG2 3.49Å; Q165-V169 PolarHBondContact O-N 3.46Å; K166-V169 PolarHBondContact O-N 3.45Å; S167-V169 PolarHBondContact O-N 3.23Å; V169-T172 WeakPolarHBondContact O-CB 3.39Å; V169-T172 PolarHBondContact O-N 2.89Å; V169-V173 HydrophobicContact CG1-CG1 4.27Å; V169-V173 VanDerWaalsContact O-CG1 3.29Å; V169-V173 WeakPolarHBondContact O-CG1 3.45Å; V169-V173 WeakPolarHBondContact O-CG2 3.19Å; V169-V173 PolarHBondContact O-N 3.39Å; V169-Y263 HydrophobicContact CB-CD1 4.01Å; V169-Y263 HydrophobicContact CB-CE1 4.24Å; V169-Y263 HydrophobicContact CG1-CD1 3.63Å; V169-Y263 HydrophobicContact CG1-CE1 4.36Å; V169-Y263 HydrophobicContact CG1-CG 4.35Å; V169-W319 HydrophobicContact CB-CH2 4.03Å; V169-W319 HydrophobicContact CB-CZ2 4.37Å; V169-W319 HydrophobicContact CG1-CE3 4.3Å; V169-W319 HydrophobicContact CG1-CH2 3.58Å; V169-W319 HydrophobicContact CG1-CZ2 3.81Å; V169-W319 HydrophobicContact CG1-CZ3 3.8Å; V169-W319 HydrophobicContact CG2-CH2 3.11Å; V169-W319 HydrophobicContact CG2-CZ2 3.67Å; V169-W319 HydrophobicContact CG2-CZ3 3.89Å
170	G	94.6	Very high	92.1	Very high	0 Å²	0	11.6 Å²	11.6	0%	0	6%	0.06	C	C	.	.	H	α-helix	trans	-60.2	-48	175.1	0	0	0	0	0	112.1	K166 S167 S168 T172 V173 L174 S213 Y263	K166-G170 PolarHBondContact O-N 3.44Å; S167-G170 WeakPolarHBondContact O-CA 3.47Å; S167-G170 PolarHBondContact O-N 3.12Å; S167-G170 VanDerWaalsContact O-N 3.16Å; S168-G170 PolarHBondContact O-N 2.87Å; G170-T172 VanDerWaalsContact C-N 3.3Å; G170-T172 PolarHBondContact O-N 2.88Å; G170-V173 WeakPolarHBondContact O-CG2 3.12Å; G170-V173 PolarHBondContact O-N 3.29Å; G170-L174 VanDerWaalsContact O-CB 3.31Å; G170-L174 WeakPolarHBondContact O-CB 3.34Å; G170-L174 VanDerWaalsContact O-CG 3.29Å; G170-L174 WeakPolarHBondContact O-CG 3.18Å; G170-L174 PolarHBondContact O-N 3.14Å; G170-S213 PolarHBondContact O-OG 2.87Å; G170-Y263 VanDerWaalsContact CA-CE1 3.45Å
171	I	95.1	Very high	92	Very high	3 Å²	3	11.2 Å²	11.2	2%	0.015	6%	0.06	C	C	.	.	H	α-helix	trans	-59.5	-45.2	176.9	-67.6	165.2	0	0	0	109.4	S167 S168 N175 W210 S213 F214	S167-I171 WeakPolarHBondContact O-CG1 3.39Å; S167-I171 PolarHBondContact O-N 3.39Å; S168-I171 PolarHBondContact O-N 2.95Å; I171-N175 VanDerWaalsContact CG2-ND2 3.29Å; I171-N175 WeakPolarHBondContact CG2-ND2 3.49Å; I171-N175 VanDerWaalsContact O-CB 3.26Å; I171-N175 WeakPolarHBondContact O-CB 3.47Å; I171-N175 PolarHBondContact O-N 2.84Å; I171-N175 PolarHBondContact O-ND2 3.35Å; I171-W210 HydrophobicContact CD1-CD2 3.82Å; I171-W210 HydrophobicContact CD1-CE3 3.77Å; I171-W210 HydrophobicContact CD1-CG 4.5Å; I171-W210 HydrophobicContact CD1-CH2 3.93Å; I171-W210 HydrophobicContact CD1-CZ2 3.97Å; I171-W210 HydrophobicContact CD1-CZ3 3.82Å; I171-W210 HydrophobicContact CG1-CD2 4.36Å; I171-S213 WeakPolarHBondContact CA-OG 3.27Å; I171-S213 PolarHBondContact N-OG 3.13Å; I171-F214 HydrophobicContact CD1-CE1 4.31Å
172	T	92.4	Very high	91.9	Very high	3 Å²	3	10.8 Å²	10.8	2%	0.018	6%	0.058	C	C	.	.	H	α-helix	trans	-59.5	-54.3	178.5	-56.1	0	0	0	0	111.4	L122 S168 V169 G170 L174 N175 L176 F315	L122-T172 HydrophobicContact CD1-CG2 3.72Å; S168-T172 PolarHBondContact O-N 3.31Å; S168-T172 PolarHBondContact O-OG1 2.85Å; V169-T172 WeakPolarHBondContact O-CB 3.39Å; V169-T172 PolarHBondContact O-N 2.89Å; G170-T172 VanDerWaalsContact C-N 3.3Å; G170-T172 PolarHBondContact O-N 2.88Å; T172-L174 PolarHBondContact O-N 3.44Å; T172-N175 PolarHBondContact O-N 3.07Å; T172-L176 HydrophobicContact CG2-CD1 4.33Å; T172-L176 WeakPolarHBondContact O-CG 3.33Å; T172-L176 PolarHBondContact O-N 3.33Å; T172-F315 HydrophobicContact CG2-CD2 4.46Å
173	V	93.6	Very high	91.5	Very high	0 Å²	0	12.4 Å²	12.4	0%	0	6%	0.064	C	C	.	.	H	α-helix	trans	-68.8	-39.9	-172.1	-59.1	0	0	0	0	111.9	V169 G170 L176 C177 Y263 P267 F315	V169-V173 HydrophobicContact CG1-CG1 4.27Å; V169-V173 VanDerWaalsContact O-CG1 3.29Å; V169-V173 WeakPolarHBondContact O-CG1 3.45Å; V169-V173 WeakPolarHBondContact O-CG2 3.19Å; V169-V173 PolarHBondContact O-N 3.39Å; G170-V173 WeakPolarHBondContact O-CG2 3.12Å; G170-V173 PolarHBondContact O-N 3.29Å; V173-L176 PolarHBondContact O-N 3.12Å; V173-C177 PolarHBondContact O-N 3.3Å; V173-C177 VanDerWaalsContact O-N 3.08Å; V173-C177 PolarHBondContact O-SG 2.94Å; V173-C177 VanDerWaalsContact O-SG 3.37Å; V173-Y263 WeakPolarHBondContact CG1-O 3.45Å; V173-Y263 HydrophobicContact CG2-CD1 4.05Å; V173-P267 HydrophobicContact CB-CB 4.27Å; V173-P267 HydrophobicContact CB-CG 4.07Å; V173-P267 HydrophobicContact CG1-CG 4.19Å; V173-F315 HydrophobicContact CG1-CE1 4.38Å; V173-F315 HydrophobicContact CG1-CE2 3.55Å; V173-F315 HydrophobicContact CG1-CZ 3.47Å; V173-F315 VanDerWaalsContact CG1-CZ 3.47Å
174	L	95.5	Very high	91	Very high	17 Å²	17	13.4 Å²	13.4	9%	0.089	7%	0.067	C	C	.	.	H	α-helix	trans	-70.2	-36.4	178.2	-67.6	174.9	0	0	0	111.7	G170 T172 C177 A178 I209 L212 F262	G170-L174 VanDerWaalsContact O-CB 3.31Å; G170-L174 WeakPolarHBondContact O-CB 3.34Å; G170-L174 VanDerWaalsContact O-CG 3.29Å; G170-L174 WeakPolarHBondContact O-CG 3.18Å; G170-L174 PolarHBondContact O-N 3.14Å; T172-L174 PolarHBondContact O-N 3.44Å; L174-C177 WeakPolarHBondContact O-CB 3.48Å; L174-C177 PolarHBondContact O-N 3.28Å; L174-A178 WeakPolarHBondContact O-CB 3.31Å; L174-A178 PolarHBondContact O-N 3.39Å; L174-I209 HydrophobicContact CB-CB 4.39Å; L174-I209 HydrophobicContact CB-CG1 4.04Å; L174-I209 HydrophobicContact CB-CG2 3.76Å; L174-I209 HydrophobicContact CD1-CG2 4.29Å; L174-L212 HydrophobicContact CD1-CB 4.13Å; L174-L212 HydrophobicContact CD1-CD2 3.79Å; L174-L212 HydrophobicContact CD1-CG 4Å; L174-L212 HydrophobicContact CD2-CD2 4.22Å; L174-F262 HydrophobicContact CD2-CZ 4.25Å
175	N	93.7	Very high	90.6	Very high	0 Å²	0	16.7 Å²	16.7	0%	0	8%	0.077	C	C	.	.	H	α-helix	trans	-65.2	-37.8	171.8	-83.5	-64.4	0	0	0	112.1	L118 S121 L122 I171 T172 C177 A178 L179	L118-N175 PolarHBondContact O-OD1 3.36Å; S121-N175 PolarHBondContact OG-ND2 3.43Å; S121-N175 PolarHBondContact OG-OD1 3.24Å; L122-N175 HydrophobicContact CB-CB 4.29Å; L122-N175 HydrophobicContact CD1-CB 4.46Å; I171-N175 VanDerWaalsContact CG2-ND2 3.29Å; I171-N175 WeakPolarHBondContact CG2-ND2 3.49Å; I171-N175 VanDerWaalsContact O-CB 3.26Å; I171-N175 WeakPolarHBondContact O-CB 3.47Å; I171-N175 PolarHBondContact O-N 2.84Å; I171-N175 PolarHBondContact O-ND2 3.35Å; T172-N175 PolarHBondContact O-N 3.07Å; N175-C177 VanDerWaalsContact C-N 3.35Å; N175-A178 PolarHBondContact O-N 3.46Å; N175-L179 WeakPolarHBondContact O-CB 3.37Å; N175-L179 VanDerWaalsContact O-CG 3.24Å; N175-L179 WeakPolarHBondContact O-CG 3.29Å; N175-L179 PolarHBondContact O-N 2.99Å
176	L	90.4	Very high	89.9	Confident	2 Å²	2	16 Å²	16	1%	0.01	8%	0.077	C	C	.	.	H	α-helix	trans	-63.5	-40.8	175.6	-71.9	175.3	0	0	0	111.9	T172 V173 S180 L311 F315	T172-L176 HydrophobicContact CG2-CD1 4.33Å; T172-L176 WeakPolarHBondContact O-CG 3.33Å; T172-L176 PolarHBondContact O-N 3.33Å; V173-L176 PolarHBondContact O-N 3.12Å; L176-S180 PolarHBondContact O-N 3.04Å; L176-S180 VanDerWaalsContact O-N 3.09Å; L176-S180 PolarHBondContact O-OG 3.34Å; L176-L311 HydrophobicContact CD2-CB 4.03Å; L176-F315 HydrophobicContact CD1-CB 3.93Å; L176-F315 HydrophobicContact CD1-CD2 4.02Å; L176-F315 HydrophobicContact CD1-CG 3.88Å
177	C	93.6	Very high	89.1	Confident	8 Å²	8	15.9 Å²	15.9	5%	0.054	8%	0.077	C	C	.	.	H	α-helix	trans	-60.9	-52	172	-71.1	0	0	0	0	111.7	V173 L174 N175 L179 S180 V181 M266 P267 C270	V173-C177 PolarHBondContact O-N 3.3Å; V173-C177 VanDerWaalsContact O-N 3.08Å; V173-C177 PolarHBondContact O-SG 2.94Å; V173-C177 VanDerWaalsContact O-SG 3.37Å; L174-C177 WeakPolarHBondContact O-CB 3.48Å; L174-C177 PolarHBondContact O-N 3.28Å; N175-C177 VanDerWaalsContact C-N 3.35Å; C177-L179 VanDerWaalsContact C-N 3.32Å; C177-L179 PolarHBondContact O-N 2.8Å; C177-S180 WeakPolarHBondContact O-CB 3.39Å; C177-S180 PolarHBondContact O-N 3.34Å; C177-V181 VanDerWaalsContact O-CG2 3.26Å; C177-V181 WeakPolarHBondContact O-CG2 3.26Å; C177-V181 PolarHBondContact O-N 2.97Å; C177-M266 HydrophobicContact CB-CE 4.48Å; C177-M266 PolarHBondContact SG-SD 3.48Å; C177-P267 VanDerWaalsContact SG-CA 3.56Å; C177-C270 VanDerWaalsContact SG-SG 3.63Å
178	A	92.6	Very high	88.2	Confident	6 Å²	6	17.2 Å²	17.2	5%	0.05	9%	0.089	C	C	.	.	H	α-helix	trans	-57	-43.9	178.2	0	0	0	0	0	112.2	L118 L174 N175 S180 V181 D182 E205 I209	L118-A178 HydrophobicContact CD1-CB 3.95Å; L118-A178 HydrophobicContact CD2-CB 4Å; L174-A178 WeakPolarHBondContact O-CB 3.31Å; L174-A178 PolarHBondContact O-N 3.39Å; N175-A178 PolarHBondContact O-N 3.46Å; A178-S180 VanDerWaalsContact C-N 3.31Å; A178-S180 PolarHBondContact O-N 3.46Å; A178-V181 PolarHBondContact O-N 3.13Å; A178-D182 WeakPolarHBondContact O-CB 3.26Å; A178-D182 PolarHBondContact O-N 3.1Å; A178-E205 HydrophobicContact CB-CG 4.44Å; A178-E205 VanDerWaalsContact CB-OE1 3.24Å; A178-E205 WeakPolarHBondContact CB-OE1 3.47Å; A178-I209 HydrophobicContact CB-CD1 3.97Å
179	L	89	Confident	87.1	Confident	5 Å²	5	19.7 Å²	19.7	3%	0.026	11%	0.106	C	C	.	.	H	α-helix	trans	-59.2	-43	175.2	-77.1	169.4	0	0	0	111.4	P115 L118 I119 N175 C177 D182 R183 V308	P115-L179 HydrophobicContact CB-CD2 4.34Å; L118-L179 HydrophobicContact CB-CD2 3.79Å; L118-L179 HydrophobicContact CB-CG 4.08Å; L118-L179 HydrophobicContact CD1-CD2 4.06Å; L118-L179 HydrophobicContact CD1-CG 4.32Å; I119-L179 HydrophobicContact CG1-CD1 4.25Å; I119-L179 HydrophobicContact CG1-CD2 4.13Å; N175-L179 WeakPolarHBondContact O-CB 3.37Å; N175-L179 VanDerWaalsContact O-CG 3.24Å; N175-L179 WeakPolarHBondContact O-CG 3.29Å; N175-L179 PolarHBondContact O-N 2.99Å; C177-L179 VanDerWaalsContact C-N 3.32Å; C177-L179 PolarHBondContact O-N 2.8Å; L179-D182 PolarHBondContact O-N 3.45Å; L179-R183 VanDerWaalsContact O-CG 3.27Å; L179-R183 WeakPolarHBondContact O-CG 3.29Å; L179-R183 PolarHBondContact O-N 2.77Å; L179-V308 HydrophobicContact CB-CG1 4.37Å; L179-V308 HydrophobicContact CB-CG2 4.45Å
180	S	88.3	Confident	85.4	Confident	9 Å²	9	26.9 Å²	26.9	6%	0.063	13%	0.132	C	C	.	.	H	α-helix	trans	-65.9	-42.5	179.7	-57.4	0	0	0	0	112.3	L176 C177 A178 R183 Y184 T271 V308	L176-S180 PolarHBondContact O-N 3.04Å; L176-S180 VanDerWaalsContact O-N 3.09Å; L176-S180 PolarHBondContact O-OG 3.34Å; C177-S180 WeakPolarHBondContact O-CB 3.39Å; C177-S180 PolarHBondContact O-N 3.34Å; A178-S180 VanDerWaalsContact C-N 3.31Å; A178-S180 PolarHBondContact O-N 3.46Å; S180-R183 PolarHBondContact O-N 2.97Å; S180-Y184 PolarHBondContact O-N 2.92Å; S180-T271 WeakPolarHBondContact OG-CG2 3.24Å; S180-V308 VanDerWaalsContact OG-CG1 3.31Å; S180-V308 WeakPolarHBondContact OG-CG1 3.26Å
181	V	89.4	Confident	83.4	Confident	41 Å²	41	31.8 Å²	31.8	25%	0.248	17%	0.167	C	C	.	.	H	α-helix	trans	-61.2	-46.4	173.7	178.2	0	0	0	0	110.2	C177 A178 R183 Y184 R185 F274	C177-V181 VanDerWaalsContact O-CG2 3.26Å; C177-V181 WeakPolarHBondContact O-CG2 3.26Å; C177-V181 PolarHBondContact O-N 2.97Å; A178-V181 PolarHBondContact O-N 3.13Å; V181-R183 VanDerWaalsContact C-N 3.34Å; V181-R183 PolarHBondContact O-N 3.47Å; V181-Y184 PolarHBondContact O-N 2.9Å; V181-R185 HydrophobicContact CG1-CG 4.29Å; V181-R185 WeakPolarHBondContact O-CB 3.48Å; V181-R185 VanDerWaalsContact O-CG 3.29Å; V181-R185 WeakPolarHBondContact O-CG 3.42Å; V181-R185 PolarHBondContact O-N 3.08Å; V181-F274 HydrophobicContact CB-CE2 4.41Å; V181-F274 HydrophobicContact CB-CZ 4.39Å; V181-F274 HydrophobicContact CG1-CZ 4.43Å; V181-F274 HydrophobicContact CG2-CD2 3.77Å; V181-F274 HydrophobicContact CG2-CE1 4.2Å; V181-F274 HydrophobicContact CG2-CE2 3.3Å; V181-F274 HydrophobicContact CG2-CG 4.42Å; V181-F274 HydrophobicContact CG2-CZ 3.55Å
182	D	85.4	Confident	81.5	Confident	6 Å²	6	35.7 Å²	35.7	3%	0.032	18%	0.181	C	C	.	.	H	α-helix	trans	-63.2	-39.5	179.2	-177.5	73	0	0	0	111.9	A178 L179 R185 A186	A178-D182 WeakPolarHBondContact O-CB 3.26Å; A178-D182 PolarHBondContact O-N 3.1Å; L179-D182 PolarHBondContact O-N 3.45Å; D182-R185 PolarHBondContact O-N 3.13Å; D182-R185 IonicContact OD1-NH1 2.69Å; D182-A186 WeakPolarHBondContact O-CB 3.42Å; D182-A186 PolarHBondContact O-N 3.22Å
183	R	83.3	Confident	79.5	Confident	37 Å²	37	42.1 Å²	42.1	14%	0.14	22%	0.22	C	C	.	.	H	α-helix	trans	-61.3	-48	173.5	-66.3	-51.3	82.4	-165.8	3.9	111.8	L179 S180 V181 A186 V187 M278 V308	L179-R183 VanDerWaalsContact O-CG 3.27Å; L179-R183 WeakPolarHBondContact O-CG 3.29Å; L179-R183 PolarHBondContact O-N 2.77Å; S180-R183 PolarHBondContact O-N 2.97Å; V181-R183 VanDerWaalsContact C-N 3.34Å; V181-R183 PolarHBondContact O-N 3.47Å; R183-A186 PolarHBondContact O-N 3.42Å; R183-V187 WeakPolarHBondContact O-CG2 3.3Å; R183-V187 PolarHBondContact O-N 3.24Å; R183-M278 HydrophobicContact CB-SD 4.4Å; R183-V308 HydrophobicContact CG-CB 4.22Å; R183-V308 HydrophobicContact CG-CG2 3.57Å
184	Y	83.3	Confident	77.7	Confident	62 Å²	62	47.6 Å²	47.6	24%	0.243	25%	0.246	C	C	.	.	H	α-helix	trans	-59.1	-49	177.1	167.8	-109.5	0	0	0	111.2	S180 V181 A186 V187 A188 F274 L277 M278	S180-Y184 PolarHBondContact O-N 2.92Å; V181-Y184 PolarHBondContact O-N 2.9Å; Y184-A186 VanDerWaalsContact C-N 3.32Å; Y184-A186 PolarHBondContact O-N 3.17Å; Y184-V187 PolarHBondContact O-N 3.03Å; Y184-A188 HydrophobicContact CE1-CB 4.45Å; Y184-A188 HydrophobicContact CE2-CB 4.1Å; Y184-A188 WeakPolarHBondContact O-CB 3.42Å; Y184-A188 PolarHBondContact O-N 3.01Å; Y184-F274 AromaticContact CD1-CD1 3.65Å; Y184-F274 HydrophobicContact CD1-CD1 3.65Å; Y184-F274 AromaticContact CD1-CE1 3.88Å; Y184-F274 HydrophobicContact CD1-CE1 3.88Å; Y184-F274 HydrophobicContact CE1-CD1 4.44Å; Y184-F274 HydrophobicContact CE1-CE1 4.44Å; Y184-F274 AromaticContact CG-CD1 3.76Å; Y184-F274 HydrophobicContact CG-CD1 3.76Å; Y184-F274 HydrophobicContact CG-CE1 4.45Å; Y184-L277 HydrophobicContact CD2-CB 3.81Å; Y184-L277 HydrophobicContact CE2-CB 3.54Å; Y184-L277 HydrophobicContact CE2-CD1 4.44Å; Y184-M278 HydrophobicContact CD2-CB 4.29Å
185	R	82.4	Confident	75.8	Confident	99 Å²	99	49 Å²	49	37%	0.374	26%	0.264	S	S	.	.	H	α-helix	trans	-60.4	-39.4	179.1	-73.5	175.8	64.8	-106.4	-1.2	112.6	V181 D182 V187 S189	V181-R185 HydrophobicContact CG1-CG 4.29Å; V181-R185 WeakPolarHBondContact O-CB 3.48Å; V181-R185 VanDerWaalsContact O-CG 3.29Å; V181-R185 WeakPolarHBondContact O-CG 3.42Å; V181-R185 PolarHBondContact O-N 3.08Å; D182-R185 PolarHBondContact O-N 3.13Å; D182-R185 IonicContact OD1-NH1 2.69Å; R185-V187 PolarHBondContact O-N 3.49Å; R185-S189 VanDerWaalsContact O-CB 3.25Å; R185-S189 WeakPolarHBondContact O-CB 3.33Å; R185-S189 PolarHBondContact O-N 3.33Å
186	A	76.8	Confident	74.2	Confident	18 Å²	18	56 Å²	56	15%	0.149	30%	0.3	C	S	.	.	H	α-helix	trans	-63.6	-29.3	176.4	0	0	0	0	0	112.6	D182 R183 Y184 R301	D182-A186 WeakPolarHBondContact O-CB 3.42Å; D182-A186 PolarHBondContact O-N 3.22Å; R183-A186 PolarHBondContact O-N 3.42Å; Y184-A186 VanDerWaalsContact C-N 3.32Å; Y184-A186 PolarHBondContact O-N 3.17Å; A186-R301 VanDerWaalsContact O-CZ 3.27Å; A186-R301 PolarHBondContact O-NH1 2.9Å
187	V	72.9	Confident	73.2	Confident	8 Å²	8	57.4 Å²	57.4	5%	0.048	32%	0.315	C	S	.	.	H	α-helix	trans	-84	-45.7	178.2	174.2	0	0	0	0	111.7	R183 Y184 R185 M278 E281 M282 R301	R183-V187 WeakPolarHBondContact O-CG2 3.3Å; R183-V187 PolarHBondContact O-N 3.24Å; Y184-V187 PolarHBondContact O-N 3.03Å; R185-V187 PolarHBondContact O-N 3.49Å; V187-M278 HydrophobicContact CB-CG 4.23Å; V187-M278 HydrophobicContact CG1-CG 4.2Å; V187-M278 HydrophobicContact CG2-CE 3.55Å; V187-M278 HydrophobicContact CG2-CG 3.99Å; V187-M278 HydrophobicContact CG2-SD 3.84Å; V187-E281 HydrophobicContact CG1-CG 4.37Å; V187-M282 HydrophobicContact CG1-CG 3.72Å; V187-M282 HydrophobicContact CG1-SD 4.48Å; V187-R301 HydrophobicContact CG2-CB 4.3Å
188	A	75.3	Confident	72.6	Confident	30 Å²	30	61.5 Å²	61.5	25%	0.248	34%	0.336	C	S	.	.	H	α-helix	trans	-70.7	-40	-179	0	0	0	0	0	112.7	Y184 R285	Y184-A188 HydrophobicContact CE1-CB 4.45Å; Y184-A188 HydrophobicContact CE2-CB 4.1Å; Y184-A188 WeakPolarHBondContact O-CB 3.42Å; Y184-A188 PolarHBondContact O-N 3.01Å; A188-R285 PolarHBondContact O-NH2 2.91Å
189	S	69.5	Low	72.2	Confident	54 Å²	54	63.3 Å²	63.3	38%	0.378	35%	0.347	S	S	.	.			trans	-96.1	105.9	178.1	-173.5	0	0	0	0	110.5	R185 S191	R185-S189 VanDerWaalsContact O-CB 3.25Å; R185-S189 WeakPolarHBondContact O-CB 3.33Å; R185-S189 PolarHBondContact O-N 3.33Å; S189-S191 VanDerWaalsContact C-N 3.34Å
190	W	55.8	Low	72.1	Confident	156 Å²	156	69.4 Å²	69.4	59%	0.591	38%	0.379	S	S	*	.	S	Bend	trans	-81.1	-12.8	179.2	-139.1	66.4	0	0	0	113.2	L294	W190-L294 HydrophobicContact CZ2-CD1 3.65Å
191	S	52	Low	72.1	Confident	103 Å²	103	74.3 Å²	74.3	72%	0.72	40%	0.403	S	S	*	.			trans	-100.7	2	-173.4	76.9	0	0	0	0	115.7	S189 V193	S189-S191 VanDerWaalsContact C-N 3.34Å; S191-V193 PolarHBondContact O-N 3.36Å
192	R	56.2	Low	72	Confident	86 Å²	86	72.5 Å²	72.5	33%	0.325	39%	0.392	S	S	.	.			trans	-74.2	94.9	175.6	-156.6	178.4	-163.2	-168.1	3.7	108.9	Q194	R192-Q194 PolarHBondContact O-N 2.85Å
193	V	51.3	Low	72.3	Confident	138 Å²	138	74.1 Å²	74.1	84%	0.836	41%	0.407	S	S	*	.			trans	-54.2	109.5	167.3	179.4	0	0	0	0	107	S191 G195	S191-V193 PolarHBondContact O-N 3.36Å; V193-G195 PolarHBondContact O-N 3.09Å
194	Q	54.3	Low	72.8	Confident	114 Å²	114	77.2 Å²	77.2	53%	0.533	43%	0.425	S	S	.	.			trans	-77.6	76.1	-179.2	-143.8	125.2	14.9	0	0	107.7	R192	R192-Q194 PolarHBondContact O-N 2.85Å
195	G	56.4	Low	73.2	Confident	47 Å²	47	76.7 Å²	76.7	49%	0.485	43%	0.425	S	S	.	.			trans	-60.6	152.6	175.5	0	0	0	0	0	111.4	V193 G197	V193-G195 PolarHBondContact O-N 3.09Å; G195-G197 PolarHBondContact O-N 2.92Å
196	I	60.6	Low	73.9	Confident	146 Å²	146	73.5 Å²	73.5	75%	0.749	42%	0.415	S	S	*	.	S	Bend	trans	-69.6	122.7	170.1	-62.9	164.7	0	0	0	107.1
197	G	68.9	Low	74.8	Confident	32 Å²	32	76.7 Å²	76.7	33%	0.33	43%	0.432	S	S	.	.	B	Isolated β-bridge	trans	133.9	161.3	-178.1	0	0	0	0	0	113.4	R112 G195 P199	R112-G197 CarbonylContact O-C 3.38Å; R112-G197 WeakPolarHBondContact O-CA 3.37Å; R112-G197 PolarHBondContact O-N 3.13Å; R112-G197 VanDerWaalsContact O-N 3.1Å; G195-G197 PolarHBondContact O-N 2.92Å; G197-P199 WeakPolarHBondContact O-CD 3.27Å
198	I	80.2	Confident	75.9	Confident	94 Å²	94	79.1 Å²	79.1	48%	0.482	45%	0.45	S	S	.	.			trans	-88.9	115.9	174.8	-57.9	173.4	0	0	0	107	A117 T202	A117-I198 HydrophobicContact CB-CD1 3.92Å; A117-I198 HydrophobicContact CB-CG1 4.09Å; A117-I198 HydrophobicContact CB-CG2 4.12Å; I198-T202 HydrophobicContact CG2-CG2 4.41Å
199	P	84.1	Confident	77	Confident	45 Å²	45	78.2 Å²	78.2	29%	0.292	44%	0.44	S	S	.	.			trans	-60.4	141.9	175.7	-20.1	32.1	0	0	0	110.3	G197 I201 T202 A203	G197-P199 WeakPolarHBondContact O-CD 3.27Å; P199-I201 PolarHBondContact O-N 3.5Å; P199-I201 VanDerWaalsContact O-N 3.13Å; P199-T202 WeakPolarHBondContact O-CB 3.17Å; P199-T202 PolarHBondContact O-N 3.04Å; P199-A203 PolarHBondContact O-N 3.39Å; P199-A203 VanDerWaalsContact O-N 3.16Å
200	L	87.4	Confident	78.3	Confident	133 Å²	133	77.9 Å²	77.9	70%	0.696	43%	0.431	S	S	*	.	H	α-helix	trans	-51.6	-38.9	174.8	178.1	62.1	0	0	0	111.7	T202 A203 I204	L200-T202 VanDerWaalsContact C-N 3.3Å; L200-T202 PolarHBondContact O-N 3.19Å; L200-A203 WeakPolarHBondContact O-CB 3.19Å; L200-A203 PolarHBondContact O-N 3.18Å; L200-A203 VanDerWaalsContact O-N 3.11Å; L200-I204 HydrophobicContact CD1-CD1 4.38Å; L200-I204 HydrophobicContact CD1-CG1 4.43Å; L200-I204 HydrophobicContact CG-CD1 3.99Å; L200-I204 HydrophobicContact CG-CG1 4.48Å; L200-I204 WeakPolarHBondContact O-CG1 3.47Å; L200-I204 PolarHBondContact O-N 3.45Å
201	I	87.6	Confident	80.3	Confident	111 Å²	111	75 Å²	75	57%	0.569	43%	0.426	S	S	*	.	H	α-helix	trans	-57.2	-42.2	176.3	-60	172.5	0	0	0	111.5	P199 I204 E205	P199-I201 PolarHBondContact O-N 3.5Å; P199-I201 VanDerWaalsContact O-N 3.13Å; I201-I204 PolarHBondContact O-N 2.85Å; I201-E205 WeakPolarHBondContact O-CB 3.23Å; I201-E205 PolarHBondContact O-N 3.35Å
202	T	89.2	Confident	82.5	Confident	3 Å²	3	73.8 Å²	73.8	2%	0.018	41%	0.411	C	S	.	.	H	α-helix	trans	-71.5	-32.6	178.3	-57.7	0	0	0	0	111.9	A117 L118 I198 P199 L200 E205 I206	A117-T202 HydrophobicContact CB-CG2 4.38Å; L118-T202 HydrophobicContact CG-CG2 4.24Å; I198-T202 HydrophobicContact CG2-CG2 4.41Å; P199-T202 WeakPolarHBondContact O-CB 3.17Å; P199-T202 PolarHBondContact O-N 3.04Å; L200-T202 VanDerWaalsContact C-N 3.3Å; L200-T202 PolarHBondContact O-N 3.19Å; T202-E205 PolarHBondContact O-N 3.44Å; T202-I206 HydrophobicContact CG2-CD1 4.2Å; T202-I206 WeakPolarHBondContact O-CG1 3.33Å; T202-I206 PolarHBondContact O-N 3.15Å
203	A	90.5	Very high	84.4	Confident	41 Å²	41	69.7 Å²	69.7	34%	0.339	40%	0.396	S	S	.	.	H	α-helix	trans	-65.4	-44.1	173	0	0	0	0	0	111.4	P199 L200 E205 I206 V207	P199-A203 PolarHBondContact O-N 3.39Å; P199-A203 VanDerWaalsContact O-N 3.16Å; L200-A203 WeakPolarHBondContact O-CB 3.19Å; L200-A203 PolarHBondContact O-N 3.18Å; L200-A203 VanDerWaalsContact O-N 3.11Å; A203-E205 VanDerWaalsContact C-N 3.33Å; A203-E205 PolarHBondContact O-N 3.41Å; A203-I206 PolarHBondContact O-N 2.92Å; A203-V207 WeakPolarHBondContact O-CG2 3.43Å; A203-V207 PolarHBondContact O-N 3.18Å
204	I	93.5	Very high	86.5	Confident	102 Å²	102	66.5 Å²	66.5	52%	0.523	37%	0.371	S	S	.	.	H	α-helix	trans	-60.3	-44.1	174.2	-66.5	167.9	0	0	0	110.5	L200 I201 V207 S208	L200-I204 HydrophobicContact CD1-CD1 4.38Å; L200-I204 HydrophobicContact CD1-CG1 4.43Å; L200-I204 HydrophobicContact CG-CD1 3.99Å; L200-I204 HydrophobicContact CG-CG1 4.48Å; L200-I204 WeakPolarHBondContact O-CG1 3.47Å; L200-I204 PolarHBondContact O-N 3.45Å; I201-I204 PolarHBondContact O-N 2.85Å; I204-V207 PolarHBondContact O-N 2.91Å; I204-S208 WeakPolarHBondContact O-CB 3.42Å; I204-S208 PolarHBondContact O-N 2.86Å; I204-S208 PolarHBondContact O-OG 3.17Å
205	E	93.4	Very high	88.6	Confident	50 Å²	50	66.2 Å²	66.2	23%	0.234	37%	0.371	C	S	.	.	H	α-helix	trans	-57.3	-49.9	176.1	-174	174	-162.5	0	0	111.3	L118 A178 I201 T202 A203 V207 S208 I209	L118-E205 HydrophobicContact CD2-CG 4.46Å; A178-E205 HydrophobicContact CB-CG 4.44Å; A178-E205 VanDerWaalsContact CB-OE1 3.24Å; A178-E205 WeakPolarHBondContact CB-OE1 3.47Å; I201-E205 WeakPolarHBondContact O-CB 3.23Å; I201-E205 PolarHBondContact O-N 3.35Å; T202-E205 PolarHBondContact O-N 3.44Å; A203-E205 VanDerWaalsContact C-N 3.33Å; A203-E205 PolarHBondContact O-N 3.41Å; E205-V207 PolarHBondContact O-N 3.45Å; E205-S208 PolarHBondContact O-N 2.94Å; E205-S208 PolarHBondContact O-OG 3.27Å; E205-I209 HydrophobicContact CG-CD1 4.23Å; E205-I209 VanDerWaalsContact O-CG1 3.28Å; E205-I209 WeakPolarHBondContact O-CG1 3.03Å; E205-I209 PolarHBondContact O-N 3.38Å
206	I	95.5	Very high	90.4	Very high	33 Å²	33	65.8 Å²	65.8	17%	0.169	36%	0.357	C	S	.	.	H	α-helix	trans	-58.6	-50	176.1	-69.4	165.9	0	0	0	111.1	A117 L118 T202 A203 S208 I209 W210	A117-I206 HydrophobicContact CB-CD1 3.86Å; L118-I206 HydrophobicContact CD2-CD1 4.47Å; L118-I206 HydrophobicContact CD2-CG1 3.78Å; T202-I206 HydrophobicContact CG2-CD1 4.2Å; T202-I206 WeakPolarHBondContact O-CG1 3.33Å; T202-I206 PolarHBondContact O-N 3.15Å; A203-I206 PolarHBondContact O-N 2.92Å; I206-S208 VanDerWaalsContact C-N 3.27Å; I206-S208 PolarHBondContact O-N 3.13Å; I206-I209 WeakPolarHBondContact O-CB 3.42Å; I206-I209 PolarHBondContact O-N 3.01Å; I206-I209 VanDerWaalsContact O-N 3.13Å; I206-W210 PolarHBondContact O-N 3.44Å; I206-W210 VanDerWaalsContact O-N 3.08Å
207	V	96.3	Very high	92	Very high	84 Å²	84	58.8 Å²	58.8	51%	0.509	32%	0.321	S	S	.	.	H	α-helix	trans	-59.4	-41.7	179.6	171.2	0	0	0	0	111	A203 I204 E205 I209 W210 I211	A203-V207 WeakPolarHBondContact O-CG2 3.43Å; A203-V207 PolarHBondContact O-N 3.18Å; I204-V207 PolarHBondContact O-N 2.91Å; E205-V207 PolarHBondContact O-N 3.45Å; V207-I209 VanDerWaalsContact C-N 3.34Å; V207-I209 PolarHBondContact O-N 3.44Å; V207-W210 PolarHBondContact O-N 2.86Å; V207-I211 HydrophobicContact CG1-CD1 3.72Å; V207-I211 HydrophobicContact CG1-CG1 4.38Å; V207-I211 WeakPolarHBondContact O-CG1 3.46Å; V207-I211 PolarHBondContact O-N 3.36Å
208	S	96.8	Very high	93.3	Very high	60 Å²	60	60.4 Å²	60.4	42%	0.42	32%	0.322	S	S	.	.	H	α-helix	trans	-63.4	-38.8	176.9	76	0	0	0	0	112.6	I204 E205 I206 W210 I211 L212	I204-S208 WeakPolarHBondContact O-CB 3.42Å; I204-S208 PolarHBondContact O-N 2.86Å; I204-S208 PolarHBondContact O-OG 3.17Å; E205-S208 PolarHBondContact O-N 2.94Å; E205-S208 PolarHBondContact O-OG 3.27Å; I206-S208 VanDerWaalsContact C-N 3.27Å; I206-S208 PolarHBondContact O-N 3.13Å; S208-W210 VanDerWaalsContact C-N 3.35Å; S208-W210 PolarHBondContact O-N 2.91Å; S208-I211 PolarHBondContact O-N 3.16Å; S208-L212 VanDerWaalsContact O-CB 3.23Å; S208-L212 WeakPolarHBondContact O-CB 3.16Å; S208-L212 PolarHBondContact O-N 3.41Å
209	I	97.3	Very high	93.8	Very high	10 Å²	10	57 Å²	57	5%	0.051	31%	0.306	C	S	.	.	H	α-helix	trans	-60.7	-46.4	176.1	-72.5	167.2	0	0	0	110.1	L118 L174 A178 E205 I206 V207 S213	L118-I209 HydrophobicContact CD2-CD1 4.11Å; L174-I209 HydrophobicContact CB-CB 4.39Å; L174-I209 HydrophobicContact CB-CG1 4.04Å; L174-I209 HydrophobicContact CB-CG2 3.76Å; L174-I209 HydrophobicContact CD1-CG2 4.29Å; A178-I209 HydrophobicContact CB-CD1 3.97Å; E205-I209 HydrophobicContact CG-CD1 4.23Å; E205-I209 VanDerWaalsContact O-CG1 3.28Å; E205-I209 WeakPolarHBondContact O-CG1 3.03Å; E205-I209 PolarHBondContact O-N 3.38Å; I206-I209 WeakPolarHBondContact O-CB 3.42Å; I206-I209 PolarHBondContact O-N 3.01Å; I206-I209 VanDerWaalsContact O-N 3.13Å; V207-I209 VanDerWaalsContact C-N 3.34Å; V207-I209 PolarHBondContact O-N 3.44Å; I209-S213 VanDerWaalsContact O-CB 3.27Å; I209-S213 WeakPolarHBondContact O-CB 3.4Å; I209-S213 PolarHBondContact O-N 3.03Å; I209-S213 PolarHBondContact O-OG 3.36Å
210	W	97.4	Very high	94.2	Very high	48 Å²	48	55 Å²	55	18%	0.182	29%	0.293	C	S	.	.	H	α-helix	trans	-65.9	-47.7	-179.5	-81.1	69.5	0	0	0	112.2	S121 L124 I128 I171 I206 V207 S208 L212 S213 F214	S121-W210 PolarHBondContact OG-NE1 3.44Å; L124-W210 HydrophobicContact CB-CZ2 4.27Å; L124-W210 HydrophobicContact CD2-CH2 3.83Å; L124-W210 HydrophobicContact CD2-CZ2 3.7Å; L124-W210 HydrophobicContact CG-CH2 3.96Å; L124-W210 HydrophobicContact CG-CZ2 3.97Å; I128-W210 HydrophobicContact CD1-CH2 3.63Å; I128-W210 HydrophobicContact CD1-CZ3 4.01Å; I171-W210 HydrophobicContact CD1-CD2 3.82Å; I171-W210 HydrophobicContact CD1-CE3 3.77Å; I171-W210 HydrophobicContact CD1-CG 4.5Å; I171-W210 HydrophobicContact CD1-CH2 3.93Å; I171-W210 HydrophobicContact CD1-CZ2 3.97Å; I171-W210 HydrophobicContact CD1-CZ3 3.82Å; I171-W210 HydrophobicContact CG1-CD2 4.36Å; I206-W210 PolarHBondContact O-N 3.44Å; I206-W210 VanDerWaalsContact O-N 3.08Å; V207-W210 PolarHBondContact O-N 2.86Å; S208-W210 VanDerWaalsContact C-N 3.35Å; S208-W210 PolarHBondContact O-N 2.91Å; W210-L212 PolarHBondContact O-N 3.03Å; W210-S213 PolarHBondContact O-N 3.38Å; W210-F214 HydrophobicContact CE3-CE1 4.05Å; W210-F214 AromaticContact CE3-CE2 3.91Å; W210-F214 HydrophobicContact CE3-CE2 3.91Å; W210-F214 AromaticContact CE3-CZ 3.4Å; W210-F214 HydrophobicContact CE3-CZ 3.4Å; W210-F214 HydrophobicContact CZ3-CE1 4.31Å; W210-F214 AromaticContact CZ3-CZ 3.69Å; W210-F214 HydrophobicContact CZ3-CZ 3.69Å; W210-F214 VanDerWaalsContact O-CG 3.3Å; W210-F214 WeakPolarHBondContact O-CG 3.41Å; W210-F214 PolarHBondContact O-N 2.92Å
211	I	97.8	Very high	94.4	Very high	94 Å²	94	50 Å²	50	48%	0.482	27%	0.271	S	S	.	.	H	α-helix	trans	-59.2	-50.3	177.4	-67.5	170.9	0	0	0	110	V207 S208 S213 F214 M215	V207-I211 HydrophobicContact CG1-CD1 3.72Å; V207-I211 HydrophobicContact CG1-CG1 4.38Å; V207-I211 WeakPolarHBondContact O-CG1 3.46Å; V207-I211 PolarHBondContact O-N 3.36Å; S208-I211 PolarHBondContact O-N 3.16Å; I211-S213 VanDerWaalsContact C-N 3.33Å; I211-S213 PolarHBondContact O-N 3.48Å; I211-F214 PolarHBondContact O-N 3.4Å; I211-M215 HydrophobicContact CG2-CG 4.23Å; I211-M215 WeakPolarHBondContact O-CB 3.31Å; I211-M215 WeakPolarHBondContact O-CG 3.49Å; I211-M215 PolarHBondContact O-N 3Å
212	L	97.1	Very high	94.6	Very high	79 Å²	79	49.5 Å²	49.5	41%	0.414	27%	0.268	S	S	.	.	H	α-helix	trans	-60.6	-43.2	179.7	-177	58.6	0	0	0	111.6	L174 S208 W210 F214 M215 L216	L174-L212 HydrophobicContact CD1-CB 4.13Å; L174-L212 HydrophobicContact CD1-CD2 3.79Å; L174-L212 HydrophobicContact CD1-CG 4Å; L174-L212 HydrophobicContact CD2-CD2 4.22Å; S208-L212 VanDerWaalsContact O-CB 3.23Å; S208-L212 WeakPolarHBondContact O-CB 3.16Å; S208-L212 PolarHBondContact O-N 3.41Å; W210-L212 PolarHBondContact O-N 3.03Å; L212-F214 PolarHBondContact O-N 3.08Å; L212-M215 PolarHBondContact O-N 3.3Å; L212-L216 HydrophobicContact CD1-CD1 4.15Å; L212-L216 HydrophobicContact CD1-CD2 4.48Å; L212-L216 HydrophobicContact CD1-CG 4.1Å; L212-L216 HydrophobicContact CG-CD1 4.09Å; L212-L216 HydrophobicContact CG-CG 4.43Å; L212-L216 VanDerWaalsContact O-CG 3.25Å; L212-L216 WeakPolarHBondContact O-CG 3.4Å; L212-L216 PolarHBondContact O-N 2.84Å
213	S	97.1	Very high	94.5	Very high	0 Å²	0	49.4 Å²	49.4	0%	0	27%	0.267	C	S	.	.	H	α-helix	trans	-61.6	-43.4	178.8	-57.8	0	0	0	0	112.3	S167 G170 I171 I209 W210 I211 A217	S167-S213 WeakPolarHBondContact O-CB 3.37Å; G170-S213 PolarHBondContact O-OG 2.87Å; I171-S213 WeakPolarHBondContact CA-OG 3.27Å; I171-S213 PolarHBondContact N-OG 3.13Å; I209-S213 VanDerWaalsContact O-CB 3.27Å; I209-S213 WeakPolarHBondContact O-CB 3.4Å; I209-S213 PolarHBondContact O-N 3.03Å; I209-S213 PolarHBondContact O-OG 3.36Å; W210-S213 PolarHBondContact O-N 3.38Å; I211-S213 VanDerWaalsContact C-N 3.33Å; I211-S213 PolarHBondContact O-N 3.48Å; S213-A217 PolarHBondContact O-N 2.96Å
214	F	96.2	Very high	94.5	Very high	70 Å²	70	49.1 Å²	49.1	31%	0.307	26%	0.258	S	S	.	.	H	α-helix	trans	-65.5	-44.3	176	-68.1	-15.1	0	0	0	111.6	F163 S167 I171 W210 I211 L212 L216 A217 I218	F163-F214 HydrophobicContact CE2-CB 4.5Å; F163-F214 WeakPolarHBondContact CE2-O 3.12Å; F163-F214 HydrophobicContact CZ-CB 4.14Å; F163-F214 HydrophobicContact CZ-CD1 4.07Å; F163-F214 HydrophobicContact CZ-CG 4.18Å; S167-F214 WeakPolarHBondContact OG-CD1 3.44Å; I171-F214 HydrophobicContact CD1-CE1 4.31Å; W210-F214 HydrophobicContact CE3-CE1 4.05Å; W210-F214 AromaticContact CE3-CE2 3.91Å; W210-F214 HydrophobicContact CE3-CE2 3.91Å; W210-F214 AromaticContact CE3-CZ 3.4Å; W210-F214 HydrophobicContact CE3-CZ 3.4Å; W210-F214 HydrophobicContact CZ3-CE1 4.31Å; W210-F214 AromaticContact CZ3-CZ 3.69Å; W210-F214 HydrophobicContact CZ3-CZ 3.69Å; W210-F214 VanDerWaalsContact O-CG 3.3Å; W210-F214 WeakPolarHBondContact O-CG 3.41Å; W210-F214 PolarHBondContact O-N 2.92Å; I211-F214 PolarHBondContact O-N 3.4Å; L212-F214 PolarHBondContact O-N 3.08Å; F214-L216 VanDerWaalsContact C-N 3.32Å; F214-L216 PolarHBondContact O-N 3.31Å; F214-A217 PolarHBondContact O-N 3.07Å; F214-A217 VanDerWaalsContact O-N 3.11Å; F214-I218 WeakPolarHBondContact O-CG1 3.04Å; F214-I218 PolarHBondContact O-N 3.01Å
215	M	96.8	Very high	94.3	Very high	109 Å²	109	46.2 Å²	46.2	54%	0.537	25%	0.245	S	C	.	.	H	α-helix	trans	-59.7	-43.3	178.7	-70	-65.4	140.8	0	0	112	I211 L212 A217 I218	I211-M215 HydrophobicContact CG2-CG 4.23Å; I211-M215 WeakPolarHBondContact O-CB 3.31Å; I211-M215 WeakPolarHBondContact O-CG 3.49Å; I211-M215 PolarHBondContact O-N 3Å; L212-M215 PolarHBondContact O-N 3.3Å; M215-A217 PolarHBondContact O-N 3.38Å; M215-I218 HydrophobicContact CE-CD1 4.24Å; M215-I218 WeakPolarHBondContact O-CB 3.28Å; M215-I218 PolarHBondContact O-N 2.87Å; M215-I218 HydrophobicContact SD-CD1 3.56Å; M215-I218 VanDerWaalsContact SD-CD1 3.56Å
216	L	94.9	Very high	94	Very high	37 Å²	37	44.8 Å²	44.8	19%	0.194	24%	0.239	C	C	.	.	H	α-helix	trans	-69.3	-18.9	178.9	-65.9	178.6	0	0	0	113.8	L212 F214 W258 F262 Y263	L212-L216 HydrophobicContact CD1-CD1 4.15Å; L212-L216 HydrophobicContact CD1-CD2 4.48Å; L212-L216 HydrophobicContact CD1-CG 4.1Å; L212-L216 HydrophobicContact CG-CD1 4.09Å; L212-L216 HydrophobicContact CG-CG 4.43Å; L212-L216 VanDerWaalsContact O-CG 3.25Å; L212-L216 WeakPolarHBondContact O-CG 3.4Å; L212-L216 PolarHBondContact O-N 2.84Å; F214-L216 VanDerWaalsContact C-N 3.32Å; F214-L216 PolarHBondContact O-N 3.31Å; L216-W258 HydrophobicContact CD1-CZ2 4.38Å; L216-W258 HydrophobicContact CD2-CH2 4.17Å; L216-W258 HydrophobicContact CD2-CZ2 3.73Å; L216-F262 HydrophobicContact CD1-CD1 3.91Å; L216-F262 HydrophobicContact CD1-CE1 3.17Å; L216-F262 HydrophobicContact CD1-CE2 4.1Å; L216-F262 HydrophobicContact CD1-CZ 3.28Å; L216-Y263 WeakPolarHBondContact CB-OH 3.33Å
217	A	95.2	Very high	93.5	Very high	0 Å²	0	44.5 Å²	44.5	0%	0	24%	0.239	C	C	.	.	H	α-helix	trans	-92.6	-11.4	178.3	0	0	0	0	0	113.7	F163 K166 S167 S213 F214 M215 P219 E220	F163-A217 HydrophobicContact CD2-CB 3.68Å; F163-A217 HydrophobicContact CE2-CB 3.88Å; F163-A217 WeakPolarHBondContact O-CB 3.28Å; K166-A217 HydrophobicContact CB-CB 3.94Å; S167-A217 WeakPolarHBondContact OG-CB 3.5Å; S213-A217 PolarHBondContact O-N 2.96Å; F214-A217 PolarHBondContact O-N 3.07Å; F214-A217 VanDerWaalsContact O-N 3.11Å; M215-A217 PolarHBondContact O-N 3.38Å; A217-P219 VanDerWaalsContact C-CD 3.42Å; A217-P219 VanDerWaalsContact C-N 3.34Å; A217-E220 WeakPolarHBondContact O-CB 3.44Å; A217-E220 PolarHBondContact O-N 3.29Å
218	I	94.3	Very high	92.9	Very high	66 Å²	66	44.5 Å²	44.5	34%	0.338	24%	0.24	S	C	.	.	H	α-helix	trans	-51.3	-43.6	-179.7	-69.8	173.1	0	0	0	113.4	F214 M215 E220 A221 I222	F214-I218 WeakPolarHBondContact O-CG1 3.04Å; F214-I218 PolarHBondContact O-N 3.01Å; M215-I218 HydrophobicContact CE-CD1 4.24Å; M215-I218 WeakPolarHBondContact O-CB 3.28Å; M215-I218 PolarHBondContact O-N 2.87Å; M215-I218 HydrophobicContact SD-CD1 3.56Å; M215-I218 VanDerWaalsContact SD-CD1 3.56Å; I218-E220 PolarHBondContact O-N 2.91Å; I218-E220 VanDerWaalsContact O-N 3.13Å; I218-A221 WeakPolarHBondContact O-CB 3.5Å; I218-A221 PolarHBondContact O-N 2.63Å; I218-I222 HydrophobicContact CG2-CD1 3.66Å; I218-I222 HydrophobicContact CG2-CG1 4.21Å; I218-I222 PolarHBondContact O-N 3.41Å; I218-I222 VanDerWaalsContact O-N 3.17Å
219	P	92.6	Very high	92	Very high	23 Å²	23	43.5 Å²	43.5	15%	0.149	23%	0.228	C	C	.	.	H	α-helix	trans	-57.7	-29.4	179.8	-27.5	37	0	0	0	113.8	A217 I222 G223 Y251	A217-P219 VanDerWaalsContact C-CD 3.42Å; A217-P219 VanDerWaalsContact C-N 3.34Å; P219-I222 PolarHBondContact O-N 2.91Å; P219-G223 PolarHBondContact O-N 2.9Å; P219-Y251 HydrophobicContact CB-CD1 4.25Å; P219-Y251 HydrophobicContact CB-CD2 3.79Å; P219-Y251 HydrophobicContact CB-CE1 3.96Å; P219-Y251 HydrophobicContact CB-CE2 3.49Å; P219-Y251 VanDerWaalsContact CB-CE2 3.49Å; P219-Y251 HydrophobicContact CB-CG 4.15Å; P219-Y251 HydrophobicContact CG-CD2 4.36Å; P219-Y251 HydrophobicContact CG-CE2 4.06Å
220	E	91.5	Very high	91	Very high	3 Å²	3	49.1 Å²	49.1	1%	0.014	26%	0.255	C	S	.	.	H	α-helix	trans	-68.5	-42.4	176.7	-58	-77.9	-164.5	0	0	111.2	P162 K166 A217 I218 I222 G223 F224 Y251 K255	P162-E220 HydrophobicContact CB-CB 4.11Å; K166-E220 HydrophobicContact CB-CG 4.18Å; K166-E220 VanDerWaalsContact CE-OE1 3.32Å; K166-E220 WeakPolarHBondContact CE-OE1 3.42Å; K166-E220 HydrophobicContact CG-CG 3.59Å; K166-E220 WeakPolarHBondContact CG-OE1 3.49Å; A217-E220 WeakPolarHBondContact O-CB 3.44Å; A217-E220 PolarHBondContact O-N 3.29Å; I218-E220 PolarHBondContact O-N 2.91Å; I218-E220 VanDerWaalsContact O-N 3.13Å; E220-I222 VanDerWaalsContact C-N 3.3Å; E220-I222 PolarHBondContact O-N 3.49Å; E220-G223 PolarHBondContact O-N 2.91Å; E220-F224 WeakPolarHBondContact O-CB 3.11Å; E220-F224 WeakPolarHBondContact O-CD2 3.3Å; E220-F224 PolarHBondContact O-N 3.5Å; E220-F224 WeakPolarHBondContact OE2-CE2 3.34Å; E220-Y251 PolarHBondContact OE1-OH 2.96Å; E220-Y251 VanDerWaalsContact OE1-OH 3.05Å; E220-K255 WeakPolarHBondContact OE1-CE 3.26Å; E220-K255 IonicContact OE1-NZ 3.63Å; E220-K255 PolarHBondContact OE1-NZ 3.45Å; E220-K255 IonicContact OE2-NZ 3.81Å; E220-K255 PolarHBondContact OE2-NZ 3.3Å
221	A	92.5	Very high	89.6	Confident	28 Å²	28	51.4 Å²	51.4	23%	0.231	26%	0.264	C	S	.	.	H	α-helix	trans	-64	-36.5	177.1	0	0	0	0	0	112.3	K159 F163 I218	K159-A221 WeakPolarHBondContact CD-O 3.38Å; K159-A221 WeakPolarHBondContact CG-O 3.29Å; K159-A221 PolarHBondContact NZ-O 3.31Å; F163-A221 HydrophobicContact CB-CB 4.04Å; F163-A221 HydrophobicContact CD2-CB 4.22Å; F163-A221 HydrophobicContact CG-CB 4.36Å; I218-A221 WeakPolarHBondContact O-CB 3.5Å; I218-A221 PolarHBondContact O-N 2.63Å
222	I	91.6	Very high	88.2	Confident	99 Å²	99	56.1 Å²	56.1	51%	0.508	28%	0.275	S	S	.	.	H	α-helix	trans	-73.1	-48.5	178.5	-62.1	174.2	0	0	0	109.8	K159 I218 P219 E220 M248	K159-I222 PolarHBondContact NZ-O 3.46Å; I218-I222 HydrophobicContact CG2-CD1 3.66Å; I218-I222 HydrophobicContact CG2-CG1 4.21Å; I218-I222 PolarHBondContact O-N 3.41Å; I218-I222 VanDerWaalsContact O-N 3.17Å; P219-I222 PolarHBondContact O-N 2.91Å; E220-I222 VanDerWaalsContact C-N 3.3Å; E220-I222 PolarHBondContact O-N 3.49Å; I222-M248 HydrophobicContact CB-SD 4.49Å; I222-M248 HydrophobicContact CG2-SD 4.13Å
223	G	87.4	Confident	87	Confident	1 Å²	1	55.1 Å²	55.1	1%	0.01	29%	0.285	C	S	.	.	H	α-helix	trans	-76.5	-29.6	-170.5	0	0	0	0	0	116.5	P219 E220 N242	P219-G223 PolarHBondContact O-N 2.9Å; E220-G223 PolarHBondContact O-N 2.91Å; G223-N242 PolarHBondContact O-N 2.72Å
224	F	89.8	Confident	85.9	Confident	35 Å²	35	60.3 Å²	60.3	15%	0.154	31%	0.309	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-79.8	127.3	179.1	-84.2	-107.7	0	0	0	111	C158 K159 P162 E220 L241	C158-F224 WeakPolarHBondContact O-CB 3.44Å; K159-F224 WeakPolarHBondContact CG-O 3.28Å; K159-F224 PolarHBondContact NZ-O 2.95Å; P162-F224 HydrophobicContact CB-CD1 4.22Å; P162-F224 HydrophobicContact CB-CD2 3.97Å; P162-F224 HydrophobicContact CB-CE1 4.35Å; P162-F224 HydrophobicContact CB-CE2 4.15Å; P162-F224 HydrophobicContact CB-CG 4.01Å; P162-F224 HydrophobicContact CB-CZ 4.31Å; P162-F224 HydrophobicContact CG-CB 4.05Å; P162-F224 HydrophobicContact CG-CD1 3.5Å; P162-F224 HydrophobicContact CG-CD2 4.07Å; P162-F224 HydrophobicContact CG-CE1 3.89Å; P162-F224 HydrophobicContact CG-CE2 4.45Å; P162-F224 HydrophobicContact CG-CG 3.58Å; P162-F224 HydrophobicContact CG-CZ 4.35Å; E220-F224 WeakPolarHBondContact O-CB 3.11Å; E220-F224 WeakPolarHBondContact O-CD2 3.3Å; E220-F224 PolarHBondContact O-N 3.5Å; E220-F224 WeakPolarHBondContact OE2-CE2 3.34Å; F224-L241 HydrophobicContact CD2-CB 4.23Å; F224-L241 HydrophobicContact CD2-CD1 3.73Å; F224-L241 HydrophobicContact CE2-CB 3.83Å; F224-L241 HydrophobicContact CE2-CD1 3.69Å; F224-L241 HydrophobicContact CE2-CG 4.35Å; F224-L241 HydrophobicContact CZ-CB 4.09Å
225	V	89.2	Confident	84.9	Confident	41 Å²	41	63 Å²	63	25%	0.248	32%	0.323	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-142.1	157.2	179.7	-64.2	0	0	0	0	110.3	V227 M240 N242	V225-V227 HydrophobicContact CG2-CG2 3.84Å; V225-V227 PolarHBondContact O-N 3.3Å; V225-M240 PolarHBondContact N-O 3.5Å; V225-M240 PolarHBondContact O-N 3.46Å; V225-M240 VanDerWaalsContact O-N 3.09Å; V225-M240 VanDerWaalsContact O-O 3.11Å; V225-N242 HydrophobicContact CG2-CB 3.41Å; V225-N242 VanDerWaalsContact CG2-CB 3.41Å
226	M	86.8	Confident	84	Confident	21 Å²	21	60 Å²	60	10%	0.103	31%	0.307	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-79.2	116.4	172.7	-70.8	-62	-66.1	0	0	109.5	W146 D149 V155 C158 R237 T238 C239	W146-M226 HydrophobicContact CB-CE 4.01Å; W146-M226 HydrophobicContact CB-SD 4.41Å; W146-M226 VanDerWaalsContact CD1-SD 3.58Å; W146-M226 HydrophobicContact CD2-SD 4.48Å; W146-M226 HydrophobicContact CG-CE 4.05Å; W146-M226 HydrophobicContact CG-SD 3.89Å; D149-M226 HydrophobicContact CB-CE 3.87Å; V155-M226 HydrophobicContact CB-CG 4.42Å; V155-M226 HydrophobicContact CG2-CB 4.37Å; V155-M226 HydrophobicContact CG2-CG 3.93Å; C158-M226 HydrophobicContact CB-CG 4.02Å; C158-M226 HydrophobicContact CB-SD 3.85Å; M226-R237 HydrophobicContact CE-CB 3.76Å; M226-T238 CarbonylContact C-O 3.49Å; M226-T238 WeakPolarHBondContact CA-O 3.47Å; M226-C239 HydrophobicContact SD-CB 3.77Å
227	V	85.6	Confident	83.3	Confident	27 Å²	27	63.1 Å²	63.1	16%	0.164	32%	0.316	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-111	128.4	-179.4	-179.5	0	0	0	0	109.5	V225 T238 M240 N242	V225-V227 HydrophobicContact CG2-CG2 3.84Å; V225-V227 PolarHBondContact O-N 3.3Å; V227-T238 PolarHBondContact N-O 3.24Å; V227-T238 PolarHBondContact O-N 2.94Å; V227-M240 HydrophobicContact CB-CE 3.79Å; V227-M240 HydrophobicContact CB-CG 3.84Å; V227-M240 HydrophobicContact CB-SD 3.79Å; V227-M240 HydrophobicContact CG1-CE 4Å; V227-M240 HydrophobicContact CG1-SD 4.03Å; V227-M240 HydrophobicContact CG2-CE 4.45Å; V227-M240 HydrophobicContact CG2-CG 3.49Å; V227-M240 VanDerWaalsContact CG2-CG 3.49Å; V227-M240 HydrophobicContact CG2-SD 3.81Å; V227-N242 HydrophobicContact CG2-CB 4.26Å
228	P	83.3	Confident	82.8	Confident	83 Å²	83	63.4 Å²	63.4	54%	0.539	32%	0.318	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-77.6	144.3	172.2	32.6	-33.1	0	0	0	111	H236 R237	P228-H236 CarbonylContact C-O 3.45Å; P228-H236 VanDerWaalsContact CA-O 3.27Å; P228-H236 WeakPolarHBondContact CA-O 3.48Å; P228-R237 HydrophobicContact CB-CG 4.4Å
229	F	77.7	Confident	82.4	Confident	39 Å²	39	60.7 Å²	60.7	17%	0.171	31%	0.305	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-146	146.8	173.3	63.8	-84.6	0	0	0	112.3	F47 H236 T238	F47-F229 HydrophobicContact CD1-CE1 4.31Å; F47-F229 AromaticContact CD1-CZ 3.96Å; F47-F229 HydrophobicContact CD1-CZ 3.96Å; F47-F229 HydrophobicContact CD2-CE1 4.48Å; F47-F229 AromaticContact CD2-CE2 3.72Å; F47-F229 HydrophobicContact CD2-CE2 3.72Å; F47-F229 AromaticContact CD2-CZ 3.46Å; F47-F229 HydrophobicContact CD2-CZ 3.46Å; F47-F229 VanDerWaalsContact CD2-CZ 3.46Å; F47-F229 HydrophobicContact CE1-CD1 4.4Å; F47-F229 AromaticContact CE1-CE1 3.44Å; F47-F229 HydrophobicContact CE1-CE1 3.44Å; F47-F229 VanDerWaalsContact CE1-CE1 3.44Å; F47-F229 HydrophobicContact CE1-CE2 4.26Å; F47-F229 AromaticContact CE1-CZ 3.38Å; F47-F229 HydrophobicContact CE1-CZ 3.38Å; F47-F229 HydrophobicContact CE2-CD1 4.48Å; F47-F229 AromaticContact CE2-CD2 3.85Å; F47-F229 HydrophobicContact CE2-CD2 3.85Å; F47-F229 AromaticContact CE2-CE1 3.71Å; F47-F229 HydrophobicContact CE2-CE1 3.71Å; F47-F229 AromaticContact CE2-CE2 2.91Å; F47-F229 HydrophobicContact CE2-CE2 2.91Å; F47-F229 AromaticContact CE2-CZ 2.84Å; F47-F229 HydrophobicContact CE2-CZ 2.84Å; F47-F229 HydrophobicContact CG-CZ 4.02Å; F47-F229 AromaticContact CZ-CD1 3.82Å; F47-F229 HydrophobicContact CZ-CD1 3.82Å; F47-F229 AromaticContact CZ-CD2 3.94Å; F47-F229 HydrophobicContact CZ-CD2 3.94Å; F47-F229 AromaticContact CZ-CE1 3.1Å; F47-F229 HydrophobicContact CZ-CE1 3.1Å; F47-F229 AromaticContact CZ-CE2 3.26Å; F47-F229 HydrophobicContact CZ-CE2 3.26Å; F47-F229 HydrophobicContact CZ-CG 4.21Å; F47-F229 AromaticContact CZ-CZ 2.78Å; F47-F229 HydrophobicContact CZ-CZ 2.78Å; F229-H236 HydrophobicContact CD1-CB 4.39Å; F229-H236 WeakPolarHBondContact CD1-O 3.32Å; F229-H236 HydrophobicContact CD2-CB 4.24Å; F229-H236 HydrophobicContact CE1-CB 3.61Å; F229-H236 HydrophobicContact CE2-CB 3.42Å; F229-H236 VanDerWaalsContact CE2-CB 3.42Å; F229-H236 AromaticContact CE2-CD2 3.86Å; F229-H236 AromaticContact CE2-CG 3.96Å; F229-H236 HydrophobicContact CZ-CB 3.02Å; F229-H236 AromaticContact CZ-CG 3.88Å; F229-H236 PolarHBondContact N-O 2.92Å; F229-H236 PolarHBondContact O-N 3.45Å; F229-T238 HydrophobicContact CD1-CG2 3.93Å; F229-T238 HydrophobicContact CE1-CG2 3.69Å
230	E	76.1	Confident	82	Confident	129 Å²	129	61.7 Å²	61.7	60%	0.603	31%	0.308	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-67.1	108.5	168.2	164.8	-123.3	-157.1	0	0	114.9	E234 Q235	E230-E234 WeakPolarHBondContact CB-O 3.38Å; E230-Q235 VanDerWaalsContact CB-NE2 3.32Å; E230-Q235 PolarHBondContact OE2-NE2 2.89Å
231	Y	68.4	Low	81.8	Confident	96 Å²	96	62.6 Å²	62.6	38%	0.376	31%	0.313	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-132.6	119.3	164.7	-168.1	-103.2	0	0	0	112.4	G233 E234	Y231-G233 PolarHBondContact O-N 2.94Å; Y231-E234 PolarHBondContact N-O 3.24Å; Y231-E234 PolarHBondContact O-N 2.89Å
232	R	67.6	Low	81.4	Confident	192 Å²	192	62.8 Å²	62.8	73%	0.725	31%	0.31	S	S	*	.	T	Hydrogen-bonded Turn	trans	51.9	35.7	179.9	-63.6	-177	177	-168	-1.9	114.2	E234	R232-E234 VanDerWaalsContact C-N 3.28Å; R232-E234 PolarHBondContact O-N 3.36Å
233	G	71.5	Confident	81	Confident	59 Å²	59	59 Å²	59	61%	0.608	29%	0.294	S	S	*	.	T	Hydrogen-bonded Turn	trans	81.1	1	179.7	0	0	0	0	0	114.7	Y231	Y231-G233 PolarHBondContact O-N 2.94Å
234	E	74.4	Confident	80.7	Confident	108 Å²	108	64 Å²	64	51%	0.505	32%	0.324	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-103.2	134.8	171.6	-67	-169.5	165	0	0	111	E230 Y231 R232 H236	E230-E234 WeakPolarHBondContact CB-O 3.38Å; Y231-E234 PolarHBondContact N-O 3.24Å; Y231-E234 PolarHBondContact O-N 2.89Å; R232-E234 VanDerWaalsContact C-N 3.28Å; R232-E234 PolarHBondContact O-N 3.36Å; E234-H236 PolarHBondContact O-CD2 3.43Å; E234-H236 IonicContact OE2-CE1 2.97Å; E234-H236 IonicContact OE2-NE2 3.79Å
235	Q	76	Confident	80.5	Confident	128 Å²	128	65.5 Å²	65.5	60%	0.598	34%	0.336	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-82	122	174	-69.5	-67.7	-32.4	0	0	109.6	E230	E230-Q235 VanDerWaalsContact CB-NE2 3.32Å; E230-Q235 PolarHBondContact OE2-NE2 2.89Å
236	H	77.1	Confident	80.4	Confident	46 Å²	46	72.2 Å²	72.2	21%	0.213	36%	0.362	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-122.9	156.4	177.2	-63.7	-78.5	0	0	0	110.7	F45 P228 F229 E234	F45-H236 AromaticContact CE1-CE1 3.93Å; P228-H236 CarbonylContact C-O 3.45Å; P228-H236 VanDerWaalsContact CA-O 3.27Å; P228-H236 WeakPolarHBondContact CA-O 3.48Å; F229-H236 HydrophobicContact CD1-CB 4.39Å; F229-H236 WeakPolarHBondContact CD1-O 3.32Å; F229-H236 HydrophobicContact CD2-CB 4.24Å; F229-H236 HydrophobicContact CE1-CB 3.61Å; F229-H236 HydrophobicContact CE2-CB 3.42Å; F229-H236 VanDerWaalsContact CE2-CB 3.42Å; F229-H236 AromaticContact CE2-CD2 3.86Å; F229-H236 AromaticContact CE2-CG 3.96Å; F229-H236 HydrophobicContact CZ-CB 3.02Å; F229-H236 AromaticContact CZ-CG 3.88Å; F229-H236 PolarHBondContact N-O 2.92Å; F229-H236 PolarHBondContact O-N 3.45Å; E234-H236 PolarHBondContact O-CD2 3.43Å; E234-H236 IonicContact OE2-CE1 2.97Å; E234-H236 IonicContact OE2-NE2 3.79Å
237	R	81.6	Confident	80.5	Confident	102 Å²	102	77 Å²	77	39%	0.385	38%	0.382	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-124.8	132.9	177.3	-58.7	178.8	75.3	-177.6	6	109.8	D149 M226 P228	D149-R237 HydrophobicContact CB-CB 4.47Å; D149-R237 PolarHBondContact O-NH1 3.25Å; M226-R237 HydrophobicContact CE-CB 3.76Å; P228-R237 HydrophobicContact CB-CG 4.4Å
238	T	82.9	Confident	80.6	Confident	6 Å²	6	75.8 Å²	75.8	4%	0.037	38%	0.375	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-134.3	154.8	178	-168.7	0	0	0	0	111.6	F47 M226 V227 F229 M240	F47-T238 HydrophobicContact CE1-CG2 3.61Å; F47-T238 WeakPolarHBondContact CE1-OG1 3.31Å; F47-T238 HydrophobicContact CZ-CG2 4.19Å; M226-T238 CarbonylContact C-O 3.49Å; M226-T238 WeakPolarHBondContact CA-O 3.47Å; V227-T238 PolarHBondContact N-O 3.24Å; V227-T238 PolarHBondContact O-N 2.94Å; F229-T238 HydrophobicContact CD1-CG2 3.93Å; F229-T238 HydrophobicContact CE1-CG2 3.69Å; T238-M240 HydrophobicContact CG2-CE 3.23Å; T238-M240 HydrophobicContact CG2-CG 4.5Å
239	C	86.7	Confident	80.9	Confident	9 Å²	9	75.4 Å²	75.4	6%	0.061	37%	0.366	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-85.4	116.4	173.1	-174.1	0	0	0	0	110	W146 C158 M226	W146-C239 HydrophobicContact CD2-CB 3.49Å; W146-C239 VanDerWaalsContact CD2-CB 3.49Å; W146-C239 HydrophobicContact CE3-CB 3.45Å; W146-C239 VanDerWaalsContact CE3-CB 3.45Å; W146-C239 HydrophobicContact CG-CB 4.12Å; W146-C239 HydrophobicContact CH2-CB 4.12Å; W146-C239 HydrophobicContact CZ2-CB 4.17Å; W146-C239 HydrophobicContact CZ3-CB 3.76Å; C158-C239 WeakPolarHBondContact CA-SG 3.4Å; C158-C239 HydrophobicContact CB-CB 3.73Å; C158-C239 WeakPolarHBondContact CB-SG 3.36Å; C158-C239 PolarHBondContact O-SG 2.97Å; C158-C239 WeakPolarHBondContact SG-CA 3.41Å; C158-C239 WeakPolarHBondContact SG-CB 3.42Å; C158-C239 CovalentContact SG-SG 2.03Å; C158-C239 PolarHBondContact SG-SG 2.74Å; M226-C239 HydrophobicContact SD-CB 3.77Å
240	M	85	Confident	81.5	Confident	44 Å²	44	79.5 Å²	79.5	22%	0.217	38%	0.384	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-142.1	157.1	178.3	62.7	172.1	84.4	0	0	111.3	V225 V227 T238 N242	V225-M240 PolarHBondContact N-O 3.5Å; V225-M240 PolarHBondContact O-N 3.46Å; V225-M240 VanDerWaalsContact O-N 3.09Å; V225-M240 VanDerWaalsContact O-O 3.11Å; V227-M240 HydrophobicContact CB-CE 3.79Å; V227-M240 HydrophobicContact CB-CG 3.84Å; V227-M240 HydrophobicContact CB-SD 3.79Å; V227-M240 HydrophobicContact CG1-CE 4Å; V227-M240 HydrophobicContact CG1-SD 4.03Å; V227-M240 HydrophobicContact CG2-CE 4.45Å; V227-M240 HydrophobicContact CG2-CG 3.49Å; V227-M240 VanDerWaalsContact CG2-CG 3.49Å; V227-M240 HydrophobicContact CG2-SD 3.81Å; T238-M240 HydrophobicContact CG2-CE 3.23Å; T238-M240 HydrophobicContact CG2-CG 4.5Å; M240-N242 PolarHBondContact O-N 2.78Å
241	L	85.5	Confident	82.1	Confident	21 Å²	21	74.3 Å²	74.3	11%	0.11	36%	0.359	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-68.6	123.1	168.6	-173.5	79.2	0	0	0	108.3	F224 M248 Y251 Q252 K255	F224-L241 HydrophobicContact CD2-CB 4.23Å; F224-L241 HydrophobicContact CD2-CD1 3.73Å; F224-L241 HydrophobicContact CE2-CB 3.83Å; F224-L241 HydrophobicContact CE2-CD1 3.69Å; F224-L241 HydrophobicContact CE2-CG 4.35Å; F224-L241 HydrophobicContact CZ-CB 4.09Å; L241-M248 HydrophobicContact CD1-CE 3.87Å; L241-Y251 HydrophobicContact CD1-CD1 4.46Å; L241-Y251 HydrophobicContact CD1-CE1 4.3Å; L241-Q252 HydrophobicContact CD2-CB 3.94Å; L241-Q252 HydrophobicContact CD2-CG 3.95Å; L241-K255 HydrophobicContact CD2-CD 4.41Å
242	N	84.8	Confident	83.1	Confident	33 Å²	33	72.2 Å²	72.2	18%	0.176	35%	0.352	C	S	.	.			trans	-123.4	114.7	176	-171.9	22.6	0	0	0	109.7	G223 V225 V227 M240 T244	G223-N242 PolarHBondContact O-N 2.72Å; V225-N242 HydrophobicContact CG2-CB 3.41Å; V225-N242 VanDerWaalsContact CG2-CB 3.41Å; V227-N242 HydrophobicContact CG2-CB 4.26Å; M240-N242 PolarHBondContact O-N 2.78Å; N242-T244 WeakPolarHBondContact ND2-CG2 3.39Å; N242-T244 PolarHBondContact O-N 3.41Å; N242-T244 VanDerWaalsContact O-N 3.11Å
243	A	83.4	Confident	84	Confident	20 Å²	20	68 Å²	68	17%	0.165	34%	0.344	C	S	.	.			trans	-79.4	92.6	176.7	0	0	0	0	0	110.6	M248 E249 Q252	A243-M248 HydrophobicContact CB-CB 4.21Å; A243-E249 HydrophobicContact CB-CB 4.33Å; A243-E249 HydrophobicContact CB-CG 3.74Å; A243-Q252 VanDerWaalsContact CB-OE1 3.24Å
244	T	80.5	Confident	84.9	Confident	104 Å²	104	67.8 Å²	67.8	64%	0.638	33%	0.331	S	S	*	.			trans	-95.3	-18.5	177.1	55.8	0	0	0	0	113.5	N242	N242-T244 WeakPolarHBondContact ND2-CG2 3.39Å; N242-T244 PolarHBondContact O-N 3.41Å; N242-T244 VanDerWaalsContact O-N 3.11Å
245	T	87.1	Confident	85.7	Confident	67 Å²	67	63.6 Å²	63.6	41%	0.411	31%	0.311	S	S	.	.	S	Bend	trans	-120.1	153.4	-179.6	69.8	0	0	0	0	110.3	F247 M248 E249	T245-F247 PolarHBondContact O-N 2.92Å; T245-F247 VanDerWaalsContact O-N 3.15Å; T245-M248 WeakPolarHBondContact O-CA 3.46Å; T245-M248 PolarHBondContact O-N 3.43Å; T245-M248 WeakPolarHBondContact OG1-CG 3.15Å; T245-M248 PolarHBondContact OG1-N 2.68Å; T245-E249 PolarHBondContact O-N 2.93Å
246	K	87	Confident	86.3	Confident	183 Å²	183	59.1 Å²	59.1	80%	0.796	29%	0.291	S	S	*	.	H	α-helix	trans	-53.4	-36.5	177.4	-66.4	-171.7	177.5	-175.7	0	113.2	F250	K246-F250 PolarHBondContact O-N 3.38Å; K246-F250 VanDerWaalsContact O-N 3.16Å
247	F	88.5	Confident	87.1	Confident	120 Å²	120	63 Å²	63	53%	0.526	30%	0.304	S	S	.	.	H	α-helix	trans	-66.1	-40.5	175.1	175.8	-97.9	0	0	0	112	T245 F250 Y251	T245-F247 PolarHBondContact O-N 2.92Å; T245-F247 VanDerWaalsContact O-N 3.15Å; F247-F250 PolarHBondContact O-N 2.81Å; F247-Y251 WeakPolarHBondContact O-CB 3.2Å; F247-Y251 PolarHBondContact O-N 2.81Å
248	M	88.4	Confident	87.7	Confident	2 Å²	2	62.6 Å²	62.6	1%	0.01	30%	0.303	C	S	.	.	H	α-helix	trans	-72.4	-30.1	178.8	-69.9	-55.4	-47.3	0	0	113	I222 L241 A243 T245 Y251 Q252	I222-M248 HydrophobicContact CB-SD 4.49Å; I222-M248 HydrophobicContact CG2-SD 4.13Å; L241-M248 HydrophobicContact CD1-CE 3.87Å; A243-M248 HydrophobicContact CB-CB 4.21Å; T245-M248 WeakPolarHBondContact O-CA 3.46Å; T245-M248 PolarHBondContact O-N 3.43Å; T245-M248 WeakPolarHBondContact OG1-CG 3.15Å; T245-M248 PolarHBondContact OG1-N 2.68Å; M248-Y251 HydrophobicContact CE-CD1 3.6Å; M248-Y251 HydrophobicContact CE-CE1 4.32Å; M248-Y251 HydrophobicContact CE-CG 4.29Å; M248-Y251 PolarHBondContact O-N 2.84Å; M248-Q252 WeakPolarHBondContact O-CB 3.47Å; M248-Q252 PolarHBondContact O-N 2.68Å
249	E	88	Confident	88.1	Confident	75 Å²	75	62.4 Å²	62.4	35%	0.35	30%	0.302	S	S	.	.	H	α-helix	trans	-61.8	-52.6	169.8	-69	174.7	164.6	0	0	110.2	A243 T245 Y251 Q252 D253	A243-E249 HydrophobicContact CB-CB 4.33Å; A243-E249 HydrophobicContact CB-CG 3.74Å; T245-E249 PolarHBondContact O-N 2.93Å; E249-Y251 VanDerWaalsContact C-N 3.3Å; E249-Y251 PolarHBondContact O-N 3.37Å; E249-Q252 PolarHBondContact O-N 3.28Å; E249-Q252 VanDerWaalsContact O-N 3.16Å; E249-D253 PolarHBondContact O-N 3.45Å
250	F	90.6	Very high	88.5	Confident	126 Å²	126	64.8 Å²	64.8	55%	0.553	31%	0.311	S	S	*	.	H	α-helix	trans	-56.1	-44.3	173.5	172.1	-98.6	0	0	0	112.1	K246 F247 Q252 D253 V254	K246-F250 PolarHBondContact O-N 3.38Å; K246-F250 VanDerWaalsContact O-N 3.16Å; F247-F250 PolarHBondContact O-N 2.81Å; F250-Q252 PolarHBondContact O-N 2.95Å; F250-D253 PolarHBondContact O-N 3.35Å; F250-V254 HydrophobicContact CD2-CG2 3.97Å; F250-V254 HydrophobicContact CE1-CG2 4.23Å; F250-V254 HydrophobicContact CE2-CG2 3.5Å; F250-V254 HydrophobicContact CZ-CB 4.3Å; F250-V254 HydrophobicContact CZ-CG2 3.65Å; F250-V254 WeakPolarHBondContact O-CG2 3.39Å; F250-V254 PolarHBondContact O-N 3.23Å
251	Y	89.8	Confident	89	Confident	19 Å²	19	64.3 Å²	64.3	8%	0.075	32%	0.317	C	S	.	.	H	α-helix	trans	-61.3	-45.5	177.7	177.8	-103.8	0	0	0	111.5	P219 E220 L241 F247 M248 E249 D253 V254 K255	P219-Y251 HydrophobicContact CB-CD1 4.25Å; P219-Y251 HydrophobicContact CB-CD2 3.79Å; P219-Y251 HydrophobicContact CB-CE1 3.96Å; P219-Y251 HydrophobicContact CB-CE2 3.49Å; P219-Y251 VanDerWaalsContact CB-CE2 3.49Å; P219-Y251 HydrophobicContact CB-CG 4.15Å; P219-Y251 HydrophobicContact CG-CD2 4.36Å; P219-Y251 HydrophobicContact CG-CE2 4.06Å; E220-Y251 PolarHBondContact OE1-OH 2.96Å; E220-Y251 VanDerWaalsContact OE1-OH 3.05Å; L241-Y251 HydrophobicContact CD1-CD1 4.46Å; L241-Y251 HydrophobicContact CD1-CE1 4.3Å; F247-Y251 WeakPolarHBondContact O-CB 3.2Å; F247-Y251 PolarHBondContact O-N 2.81Å; M248-Y251 HydrophobicContact CE-CD1 3.6Å; M248-Y251 HydrophobicContact CE-CE1 4.32Å; M248-Y251 HydrophobicContact CE-CG 4.29Å; M248-Y251 PolarHBondContact O-N 2.84Å; E249-Y251 VanDerWaalsContact C-N 3.3Å; E249-Y251 PolarHBondContact O-N 3.37Å; Y251-D253 VanDerWaalsContact C-N 3.25Å; Y251-D253 PolarHBondContact O-N 2.89Å; Y251-V254 PolarHBondContact O-N 3Å; Y251-K255 HydrophobicContact CE1-CB 4.29Å; Y251-K255 HydrophobicContact CE1-CD 3.74Å; Y251-K255 HydrophobicContact CE1-CG 4.27Å; Y251-K255 HydrophobicContact CE2-CB 4.44Å; Y251-K255 WeakPolarHBondContact O-CA 3.5Å; Y251-K255 WeakPolarHBondContact O-CB 3.3Å; Y251-K255 PolarHBondContact O-N 3.47Å
252	Q	87.7	Confident	89.4	Confident	52 Å²	52	65.2 Å²	65.2	24%	0.243	32%	0.32	C	S	.	.	H	α-helix	trans	-58.6	-39	176.7	-179.8	171.9	-16.4	0	0	111.7	L241 A243 M248 E249 F250	L241-Q252 HydrophobicContact CD2-CB 3.94Å; L241-Q252 HydrophobicContact CD2-CG 3.95Å; A243-Q252 VanDerWaalsContact CB-OE1 3.24Å; M248-Q252 WeakPolarHBondContact O-CB 3.47Å; M248-Q252 PolarHBondContact O-N 2.68Å; E249-Q252 PolarHBondContact O-N 3.28Å; E249-Q252 VanDerWaalsContact O-N 3.16Å; F250-Q252 PolarHBondContact O-N 2.95Å
253	D	87.2	Confident	89.8	Confident	104 Å²	104	63.8 Å²	63.8	56%	0.556	31%	0.313	S	S	*	.	H	α-helix	trans	-74.2	-29.7	178.8	-72	-18.8	0	0	0	113.8	E249 F250 Y251 K330	E249-D253 PolarHBondContact O-N 3.45Å; F250-D253 PolarHBondContact O-N 3.35Å; Y251-D253 VanDerWaalsContact C-N 3.25Å; Y251-D253 PolarHBondContact O-N 2.89Å; D253-K330 VanDerWaalsContact C-NZ 3.26Å; D253-K330 WeakPolarHBondContact O-CE 3.36Å; D253-K330 PolarHBondContact O-NZ 3.37Å
254	V	90.7	Very high	90.3	Very high	55 Å²	55	63.6 Å²	63.6	33%	0.333	31%	0.308	S	S	.	.	H	α-helix	trans	-99.6	-18.2	-178.5	-178.9	0	0	0	0	112.6	F250 Y251 D256 W257 W258	F250-V254 HydrophobicContact CD2-CG2 3.97Å; F250-V254 HydrophobicContact CE1-CG2 4.23Å; F250-V254 HydrophobicContact CE2-CG2 3.5Å; F250-V254 HydrophobicContact CZ-CB 4.3Å; F250-V254 HydrophobicContact CZ-CG2 3.65Å; F250-V254 WeakPolarHBondContact O-CG2 3.39Å; F250-V254 PolarHBondContact O-N 3.23Å; Y251-V254 PolarHBondContact O-N 3Å; V254-D256 PolarHBondContact O-N 2.88Å; V254-W257 PolarHBondContact O-N 3.42Å; V254-W257 VanDerWaalsContact O-N 3.14Å; V254-W258 HydrophobicContact CG1-CB 4.21Å; V254-W258 WeakPolarHBondContact O-CB 3.4Å; V254-W258 PolarHBondContact O-N 3.2Å
255	K	90.3	Very high	91	Very high	19 Å²	19	60.5 Å²	60.5	8%	0.083	29%	0.29	C	S	.	.	H	α-helix	trans	-49	-53.9	-170.2	170	174.8	175.7	163.9	0	113.9	E220 L241 Y251 W257 W258 L259	E220-K255 WeakPolarHBondContact OE1-CE 3.26Å; E220-K255 IonicContact OE1-NZ 3.63Å; E220-K255 PolarHBondContact OE1-NZ 3.45Å; E220-K255 IonicContact OE2-NZ 3.81Å; E220-K255 PolarHBondContact OE2-NZ 3.3Å; L241-K255 HydrophobicContact CD2-CD 4.41Å; Y251-K255 HydrophobicContact CE1-CB 4.29Å; Y251-K255 HydrophobicContact CE1-CD 3.74Å; Y251-K255 HydrophobicContact CE1-CG 4.27Å; Y251-K255 HydrophobicContact CE2-CB 4.44Å; Y251-K255 WeakPolarHBondContact O-CA 3.5Å; Y251-K255 WeakPolarHBondContact O-CB 3.3Å; Y251-K255 PolarHBondContact O-N 3.47Å; K255-W257 PolarHBondContact O-N 2.68Å; K255-W258 PolarHBondContact O-N 2.98Å; K255-L259 HydrophobicContact CG-CD1 3.77Å; K255-L259 HydrophobicContact CG-CG 4.25Å; K255-L259 WeakPolarHBondContact O-CB 3.33Å; K255-L259 WeakPolarHBondContact O-CG 3.18Å; K255-L259 PolarHBondContact O-N 3.39Å
256	D	90.2	Very high	91.3	Very high	34 Å²	34	60.8 Å²	60.8	18%	0.182	29%	0.288	C	S	.	.	H	α-helix	trans	-68.1	-36.5	-174.6	-65.1	-47.9	0	0	0	112.5	V254 L259 F260 I327	V254-D256 PolarHBondContact O-N 2.88Å; D256-L259 PolarHBondContact O-N 2.85Å; D256-F260 WeakPolarHBondContact O-CB 2.96Å; D256-F260 PolarHBondContact O-N 3.32Å; D256-I327 HydrophobicContact CB-CD1 4.13Å
257	W	93.1	Very high	91.5	Very high	127 Å²	127	52.1 Å²	52.1	48%	0.481	25%	0.25	S	C	.	.	H	α-helix	trans	-67.6	-43.6	173.4	-70.5	113.5	0	0	0	112	V254 K255 F260 G261 I327 T331	V254-W257 PolarHBondContact O-N 3.42Å; V254-W257 VanDerWaalsContact O-N 3.14Å; K255-W257 PolarHBondContact O-N 2.68Å; W257-F260 PolarHBondContact O-N 3.3Å; W257-G261 PolarHBondContact O-N 3.49Å; W257-I327 HydrophobicContact CD2-CD1 3.91Å; W257-I327 HydrophobicContact CE3-CD1 3.89Å; W257-I327 HydrophobicContact CG-CD1 4.45Å; W257-I327 HydrophobicContact CH2-CD1 4.4Å; W257-I327 HydrophobicContact CH2-CG2 4Å; W257-I327 HydrophobicContact CZ2-CD1 4.42Å; W257-I327 HydrophobicContact CZ2-CG2 4.36Å; W257-I327 HydrophobicContact CZ3-CD1 4.14Å; W257-I327 HydrophobicContact CZ3-CG2 4.42Å; W257-T331 HydrophobicContact CZ2-CG2 4.04Å
258	W	93.9	Very high	91.7	Very high	94 Å²	94	48.5 Å²	48.5	36%	0.356	24%	0.236	S	C	.	.	H	α-helix	trans	-59.5	-47.3	173.7	162.7	-103.4	0	0	0	111.3	L216 V254 K255 G261 F262 Y263	L216-W258 HydrophobicContact CD1-CZ2 4.38Å; L216-W258 HydrophobicContact CD2-CH2 4.17Å; L216-W258 HydrophobicContact CD2-CZ2 3.73Å; V254-W258 HydrophobicContact CG1-CB 4.21Å; V254-W258 WeakPolarHBondContact O-CB 3.4Å; V254-W258 PolarHBondContact O-N 3.2Å; K255-W258 PolarHBondContact O-N 2.98Å; W258-G261 PolarHBondContact O-N 3.39Å; W258-F262 HydrophobicContact CD2-CB 4.25Å; W258-F262 HydrophobicContact CE3-CB 4.26Å; W258-F262 HydrophobicContact CH2-CB 3.87Å; W258-F262 AromaticContact CH2-CD2 3.55Å; W258-F262 HydrophobicContact CH2-CD2 3.55Å; W258-F262 HydrophobicContact CH2-CE2 4.25Å; W258-F262 AromaticContact CH2-CG 3.71Å; W258-F262 HydrophobicContact CH2-CG 3.71Å; W258-F262 HydrophobicContact CZ2-CB 3.82Å; W258-F262 HydrophobicContact CZ2-CD1 4.15Å; W258-F262 HydrophobicContact CZ2-CD2 4Å; W258-F262 AromaticContact CZ2-CG 3.7Å; W258-F262 HydrophobicContact CZ2-CG 3.7Å; W258-F262 HydrophobicContact CZ3-CB 4.09Å; W258-F262 HydrophobicContact CZ3-CD2 4.19Å; W258-F262 HydrophobicContact CZ3-CG 4.37Å; W258-F262 WeakPolarHBondContact O-CB 3.28Å; W258-F262 PolarHBondContact O-N 2.9Å; W258-Y263 AromaticContact NE1-CE2 3.91Å
259	L	92.4	Very high	92	Very high	3 Å²	3	52.3 Å²	52.3	2%	0.016	26%	0.259	C	S	.	.	I	π-helix	trans	-62.5	-44.5	178.5	-73.2	175.8	0	0	0	111.2	K166 K255 D256 Y263 F264	K166-L259 HydrophobicContact CD-CD2 4.2Å; K255-L259 HydrophobicContact CG-CD1 3.77Å; K255-L259 HydrophobicContact CG-CG 4.25Å; K255-L259 WeakPolarHBondContact O-CB 3.33Å; K255-L259 WeakPolarHBondContact O-CG 3.18Å; K255-L259 PolarHBondContact O-N 3.39Å; D256-L259 PolarHBondContact O-N 2.85Å; L259-Y263 HydrophobicContact CD2-CD2 3.53Å; L259-Y263 HydrophobicContact CD2-CE2 3.57Å; L259-Y263 HydrophobicContact CD2-CG 4.36Å; L259-Y263 WeakPolarHBondContact O-CA 3.17Å; L259-Y263 VanDerWaalsContact O-CB 3.29Å; L259-Y263 WeakPolarHBondContact O-CB 3.33Å; L259-Y263 PolarHBondContact O-N 3.29Å; L259-F264 PolarHBondContact O-N 3.14Å
260	F	94.2	Very high	92.2	Very high	59 Å²	59	49.5 Å²	49.5	26%	0.259	25%	0.248	S	C	.	.	I	π-helix	trans	-63	-46.9	175.5	178.9	-113.2	0	0	0	112	D256 W257 F264 C265 H323	D256-F260 WeakPolarHBondContact O-CB 2.96Å; D256-F260 PolarHBondContact O-N 3.32Å; W257-F260 PolarHBondContact O-N 3.3Å; F260-F264 HydrophobicContact CD2-CB 4.18Å; F260-F264 AromaticContact CD2-CD1 3.75Å; F260-F264 HydrophobicContact CD2-CD1 3.75Å; F260-F264 HydrophobicContact CD2-CG 4.23Å; F260-F264 AromaticContact CE2-CD1 3.38Å; F260-F264 HydrophobicContact CE2-CD1 3.38Å; F260-F264 AromaticContact CE2-CE1 3.79Å; F260-F264 HydrophobicContact CE2-CE1 3.79Å; F260-F264 HydrophobicContact CE2-CG 4.27Å; F260-F264 HydrophobicContact CZ-CD1 4.24Å; F260-F264 WeakPolarHBondContact O-CA 3.22Å; F260-F264 VanDerWaalsContact O-CB 3.27Å; F260-F264 WeakPolarHBondContact O-CB 3.22Å; F260-F264 PolarHBondContact O-N 2.91Å; F260-C265 VanDerWaalsContact CE1-SG 3.55Å; F260-C265 VanDerWaalsContact CZ-SG 3.59Å; F260-C265 PolarHBondContact O-N 3.25Å; F260-H323 HydrophobicContact CD2-CB 3.86Å
261	G	95.1	Very high	92.1	Very high	33 Å²	33	44 Å²	44	34%	0.34	22%	0.224	S	C	.	.	I	π-helix	trans	-64.3	-54.2	179.8	0	0	0	0	0	112.9	W257 W258 C265 M266	W257-G261 PolarHBondContact O-N 3.49Å; W258-G261 PolarHBondContact O-N 3.39Å; G261-C265 WeakPolarHBondContact O-CB 3.47Å; G261-C265 PolarHBondContact O-N 3.39Å; G261-M266 PolarHBondContact O-N 2.95Å
262	F	94.2	Very high	92.2	Very high	41 Å²	41	45.4 Å²	45.4	18%	0.18	24%	0.24	C	C	.	.	I	π-helix	trans	-81.8	-45.7	-172.5	-172	-88	0	0	0	113.3	L174 L216 W258 M266	L174-F262 HydrophobicContact CD2-CZ 4.25Å; L216-F262 HydrophobicContact CD1-CD1 3.91Å; L216-F262 HydrophobicContact CD1-CE1 3.17Å; L216-F262 HydrophobicContact CD1-CE2 4.1Å; L216-F262 HydrophobicContact CD1-CZ 3.28Å; W258-F262 HydrophobicContact CD2-CB 4.25Å; W258-F262 HydrophobicContact CE3-CB 4.26Å; W258-F262 HydrophobicContact CH2-CB 3.87Å; W258-F262 AromaticContact CH2-CD2 3.55Å; W258-F262 HydrophobicContact CH2-CD2 3.55Å; W258-F262 HydrophobicContact CH2-CE2 4.25Å; W258-F262 AromaticContact CH2-CG 3.71Å; W258-F262 HydrophobicContact CH2-CG 3.71Å; W258-F262 HydrophobicContact CZ2-CB 3.82Å; W258-F262 HydrophobicContact CZ2-CD1 4.15Å; W258-F262 HydrophobicContact CZ2-CD2 4Å; W258-F262 AromaticContact CZ2-CG 3.7Å; W258-F262 HydrophobicContact CZ2-CG 3.7Å; W258-F262 HydrophobicContact CZ3-CB 4.09Å; W258-F262 HydrophobicContact CZ3-CD2 4.19Å; W258-F262 HydrophobicContact CZ3-CG 4.37Å; W258-F262 WeakPolarHBondContact O-CB 3.28Å; W258-F262 PolarHBondContact O-N 2.9Å; F262-M266 WeakPolarHBondContact O-CB 3.05Å
263	Y	93.3	Very high	92.4	Very high	3 Å²	3	47.2 Å²	47.2	1%	0.012	25%	0.25	C	S	.	.	I	π-helix	trans	-87.3	-23.4	-175	-67.4	-98	0	0	0	112.7	V169 G170 V173 L216 W258 L259 P267 F315	V169-Y263 HydrophobicContact CB-CD1 4.01Å; V169-Y263 HydrophobicContact CB-CE1 4.24Å; V169-Y263 HydrophobicContact CG1-CD1 3.63Å; V169-Y263 HydrophobicContact CG1-CE1 4.36Å; V169-Y263 HydrophobicContact CG1-CG 4.35Å; G170-Y263 VanDerWaalsContact CA-CE1 3.45Å; V173-Y263 WeakPolarHBondContact CG1-O 3.45Å; V173-Y263 HydrophobicContact CG2-CD1 4.05Å; L216-Y263 WeakPolarHBondContact CB-OH 3.33Å; W258-Y263 AromaticContact NE1-CE2 3.91Å; L259-Y263 HydrophobicContact CD2-CD2 3.53Å; L259-Y263 HydrophobicContact CD2-CE2 3.57Å; L259-Y263 HydrophobicContact CD2-CG 4.36Å; L259-Y263 WeakPolarHBondContact O-CA 3.17Å; L259-Y263 VanDerWaalsContact O-CB 3.29Å; L259-Y263 WeakPolarHBondContact O-CB 3.33Å; L259-Y263 PolarHBondContact O-N 3.29Å; Y263-P267 VanDerWaalsContact O-CG 3.29Å; Y263-P267 WeakPolarHBondContact O-CG 3.34Å; Y263-F315 VanDerWaalsContact O-CZ 3.22Å; Y263-F315 WeakPolarHBondContact O-CZ 3.29Å
264	F	93.7	Very high	92.5	Very high	16 Å²	16	44.5 Å²	44.5	7%	0.07	23%	0.234	C	C	.	.	I	π-helix	trans	-108.5	-57.4	-179.6	-176.4	-96.3	0	0	0	113.2	L259 F260 P267 L268 F315 W319 F320 H323	L259-F264 PolarHBondContact O-N 3.14Å; F260-F264 HydrophobicContact CD2-CB 4.18Å; F260-F264 AromaticContact CD2-CD1 3.75Å; F260-F264 HydrophobicContact CD2-CD1 3.75Å; F260-F264 HydrophobicContact CD2-CG 4.23Å; F260-F264 AromaticContact CE2-CD1 3.38Å; F260-F264 HydrophobicContact CE2-CD1 3.38Å; F260-F264 AromaticContact CE2-CE1 3.79Å; F260-F264 HydrophobicContact CE2-CE1 3.79Å; F260-F264 HydrophobicContact CE2-CG 4.27Å; F260-F264 HydrophobicContact CZ-CD1 4.24Å; F260-F264 WeakPolarHBondContact O-CA 3.22Å; F260-F264 VanDerWaalsContact O-CB 3.27Å; F260-F264 WeakPolarHBondContact O-CB 3.22Å; F260-F264 PolarHBondContact O-N 2.91Å; F264-P267 VanDerWaalsContact O-CD 3.3Å; F264-P267 WeakPolarHBondContact O-CD 3.29Å; F264-P267 VanDerWaalsContact O-CG 3.28Å; F264-P267 WeakPolarHBondContact O-CG 3.08Å; F264-L268 HydrophobicContact CD1-CD1 3.96Å; F264-L268 HydrophobicContact CD2-CD1 4.45Å; F264-L268 HydrophobicContact CE1-CD1 3.54Å; F264-L268 HydrophobicContact CE2-CD1 4.08Å; F264-L268 HydrophobicContact CG-CD1 4.4Å; F264-L268 HydrophobicContact CZ-CD1 3.6Å; F264-L268 VanDerWaalsContact O-CG 3.28Å; F264-L268 WeakPolarHBondContact O-CG 3.44Å; F264-F315 HydrophobicContact CD2-CE1 4.31Å; F264-W319 HydrophobicContact CD2-CB 4Å; F264-W319 HydrophobicContact CE2-CB 4.29Å; F264-F320 HydrophobicContact CE1-CD2 4.24Å; F264-F320 HydrophobicContact CE2-CB 3.91Å; F264-F320 HydrophobicContact CZ-CB 3.87Å; F264-F320 AromaticContact CZ-CD2 3.77Å; F264-F320 HydrophobicContact CZ-CD2 3.77Å; F264-F320 HydrophobicContact CZ-CG 4.32Å; F264-H323 AromaticContact CD2-CD2 3.87Å
265	C	95.2	Very high	92.2	Very high	39 Å²	39	45.9 Å²	45.9	26%	0.264	23%	0.234	S	C	.	.	I	π-helix	trans	-69.9	-44.2	-175	-65.6	0	0	0	0	113.1	F260 G261 L268 V269	F260-C265 VanDerWaalsContact CE1-SG 3.55Å; F260-C265 VanDerWaalsContact CZ-SG 3.59Å; F260-C265 PolarHBondContact O-N 3.25Å; G261-C265 WeakPolarHBondContact O-CB 3.47Å; G261-C265 PolarHBondContact O-N 3.39Å; C265-L268 PolarHBondContact O-N 3.15Å; C265-V269 WeakPolarHBondContact O-CB 3.01Å; C265-V269 WeakPolarHBondContact O-CG2 3.25Å; C265-V269 PolarHBondContact O-N 3.47Å
266	M	94.1	Very high	92.1	Very high	72 Å²	72	48.8 Å²	48.8	36%	0.355	25%	0.253	S	S	.	.	H	α-helix	trans	-54.8	-50.4	-179.1	-177.3	-83.7	177.3	0	0	113.5	C177 G261 F262 L268 V269 C270	C177-M266 HydrophobicContact CB-CE 4.48Å; C177-M266 PolarHBondContact SG-SD 3.48Å; G261-M266 PolarHBondContact O-N 2.95Å; F262-M266 WeakPolarHBondContact O-CB 3.05Å; M266-L268 VanDerWaalsContact C-N 3.35Å; M266-L268 PolarHBondContact O-N 3.42Å; M266-V269 PolarHBondContact O-N 2.83Å; M266-C270 HydrophobicContact CE-CB 4.45Å; M266-C270 WeakPolarHBondContact O-CB 3.43Å; M266-C270 PolarHBondContact O-N 3.25Å
267	P	91.4	Very high	91.9	Very high	1 Å²	1	50.7 Å²	50.7	1%	0.006	26%	0.263	C	S	.	.	H	α-helix	trans	-64.8	-37.3	178.2	24.3	-34.4	0	0	0	112.8	V173 C177 Y263 F264 T271 F315	V173-P267 HydrophobicContact CB-CB 4.27Å; V173-P267 HydrophobicContact CB-CG 4.07Å; V173-P267 HydrophobicContact CG1-CG 4.19Å; C177-P267 VanDerWaalsContact SG-CA 3.56Å; Y263-P267 VanDerWaalsContact O-CG 3.29Å; Y263-P267 WeakPolarHBondContact O-CG 3.34Å; F264-P267 VanDerWaalsContact O-CD 3.3Å; F264-P267 WeakPolarHBondContact O-CD 3.29Å; F264-P267 VanDerWaalsContact O-CG 3.28Å; F264-P267 WeakPolarHBondContact O-CG 3.08Å; P267-T271 VanDerWaalsContact O-CB 3.25Å; P267-T271 WeakPolarHBondContact O-CB 3.38Å; P267-T271 WeakPolarHBondContact O-CG2 3Å; P267-T271 PolarHBondContact O-N 3.32Å; P267-T271 PolarHBondContact O-OG1 2.98Å; P267-F315 HydrophobicContact CG-CE1 3.81Å; P267-F315 HydrophobicContact CG-CZ 4.27Å
268	L	92.6	Very high	91.4	Very high	45 Å²	45	45 Å²	45	24%	0.236	24%	0.242	C	C	.	.	H	α-helix	trans	-64.8	-44.4	176.6	-62.8	177.8	0	0	0	112.1	F264 C265 M266 T271 A272 V312 A316	F264-L268 HydrophobicContact CD1-CD1 3.96Å; F264-L268 HydrophobicContact CD2-CD1 4.45Å; F264-L268 HydrophobicContact CE1-CD1 3.54Å; F264-L268 HydrophobicContact CE2-CD1 4.08Å; F264-L268 HydrophobicContact CG-CD1 4.4Å; F264-L268 HydrophobicContact CZ-CD1 3.6Å; F264-L268 VanDerWaalsContact O-CG 3.28Å; F264-L268 WeakPolarHBondContact O-CG 3.44Å; C265-L268 PolarHBondContact O-N 3.15Å; M266-L268 VanDerWaalsContact C-N 3.35Å; M266-L268 PolarHBondContact O-N 3.42Å; L268-T271 WeakPolarHBondContact CA-OG1 3.37Å; L268-T271 PolarHBondContact O-OG1 3.05Å; L268-A272 WeakPolarHBondContact O-CB 3.41Å; L268-A272 PolarHBondContact O-N 3.37Å; L268-V312 HydrophobicContact CD2-CG1 3.64Å; L268-A316 HydrophobicContact CD1-CB 4.4Å; L268-A316 HydrophobicContact CD2-CB 3.73Å
269	V	94.3	Very high	90.8	Very high	82 Å²	82	43 Å²	43	50%	0.497	24%	0.24	S	C	.	.	H	α-helix	trans	-66.9	-47	177.8	172	0	0	0	0	110.6	C265 M266 T271 A272 I273	C265-V269 WeakPolarHBondContact O-CB 3.01Å; C265-V269 WeakPolarHBondContact O-CG2 3.25Å; C265-V269 PolarHBondContact O-N 3.47Å; M266-V269 PolarHBondContact O-N 2.83Å; V269-T271 PolarHBondContact O-N 2.83Å; V269-A272 PolarHBondContact O-N 3.28Å; V269-I273 HydrophobicContact CG1-CD1 3.66Å; V269-I273 HydrophobicContact CG1-CG1 4.37Å; V269-I273 WeakPolarHBondContact O-CB 3.39Å; V269-I273 VanDerWaalsContact O-CG1 3.23Å; V269-I273 WeakPolarHBondContact O-CG1 3.46Å; V269-I273 PolarHBondContact O-N 2.66Å
270	C	93	Very high	90.3	Very high	16 Å²	16	46.1 Å²	46.1	11%	0.108	26%	0.261	C	S	.	.	H	α-helix	trans	-55.8	-52.3	177.8	179.2	0	0	0	0	111.1	C177 M266 I273 F274	C177-C270 VanDerWaalsContact SG-SG 3.63Å; M266-C270 HydrophobicContact CE-CB 4.45Å; M266-C270 WeakPolarHBondContact O-CB 3.43Å; M266-C270 PolarHBondContact O-N 3.25Å; C270-I273 PolarHBondContact O-N 2.95Å; C270-F274 WeakPolarHBondContact O-CD2 3.05Å; C270-F274 PolarHBondContact O-N 3.45Å; C270-F274 VanDerWaalsContact SG-CE2 3.58Å
271	T	88.9	Confident	89.7	Confident	9 Å²	9	45.5 Å²	45.5	6%	0.055	26%	0.259	C	S	.	.	H	α-helix	trans	-66	-40.6	-179.4	56	0	0	0	0	112.1	S180 P267 L268 V269 I273 F274 Y275 V312	S180-T271 WeakPolarHBondContact OG-CG2 3.24Å; P267-T271 VanDerWaalsContact O-CB 3.25Å; P267-T271 WeakPolarHBondContact O-CB 3.38Å; P267-T271 WeakPolarHBondContact O-CG2 3Å; P267-T271 PolarHBondContact O-N 3.32Å; P267-T271 PolarHBondContact O-OG1 2.98Å; L268-T271 WeakPolarHBondContact CA-OG1 3.37Å; L268-T271 PolarHBondContact O-OG1 3.05Å; V269-T271 PolarHBondContact O-N 2.83Å; T271-I273 PolarHBondContact O-N 3.26Å; T271-F274 PolarHBondContact O-N 3.23Å; T271-Y275 WeakPolarHBondContact O-CB 3.28Å; T271-Y275 PolarHBondContact O-N 2.92Å; T271-V312 HydrophobicContact CG2-CB 4.32Å; T271-V312 HydrophobicContact CG2-CG1 4.08Å; T271-V312 HydrophobicContact CG2-CG2 3.28Å; T271-V312 VanDerWaalsContact OG1-CG1 3.3Å; T271-V312 WeakPolarHBondContact OG1-CG1 3.45Å
272	A	90.3	Very high	88.6	Confident	50 Å²	50	45.6 Å²	45.6	41%	0.413	25%	0.251	S	S	.	.	H	α-helix	trans	-60.8	-44.5	174.7	0	0	0	0	0	111.9	L268 V269 T276	L268-A272 WeakPolarHBondContact O-CB 3.41Å; L268-A272 PolarHBondContact O-N 3.37Å; V269-A272 PolarHBondContact O-N 3.28Å; A272-T276 VanDerWaalsContact O-CB 3.28Å; A272-T276 WeakPolarHBondContact O-CB 3.3Å; A272-T276 PolarHBondContact O-N 3.19Å; A272-T276 PolarHBondContact O-OG1 2.97Å
273	I	92	Very high	87.6	Confident	89 Å²	89	47.3 Å²	47.3	46%	0.456	26%	0.262	S	S	.	.	H	α-helix	trans	-61.6	-55.4	176.8	-69.5	167.1	0	0	0	110.1	V269 C270 T271 Y275 T276 L277	V269-I273 HydrophobicContact CG1-CD1 3.66Å; V269-I273 HydrophobicContact CG1-CG1 4.37Å; V269-I273 WeakPolarHBondContact O-CB 3.39Å; V269-I273 VanDerWaalsContact O-CG1 3.23Å; V269-I273 WeakPolarHBondContact O-CG1 3.46Å; V269-I273 PolarHBondContact O-N 2.66Å; C270-I273 PolarHBondContact O-N 2.95Å; T271-I273 PolarHBondContact O-N 3.26Å; I273-Y275 VanDerWaalsContact C-N 3.32Å; I273-Y275 PolarHBondContact O-N 3.46Å; I273-T276 PolarHBondContact O-N 3.31Å; I273-L277 HydrophobicContact CG2-CD1 3.87Å; I273-L277 HydrophobicContact CG2-CG 4.32Å; I273-L277 WeakPolarHBondContact O-CB 3.47Å; I273-L277 VanDerWaalsContact O-CG 3.31Å; I273-L277 WeakPolarHBondContact O-CG 3.47Å; I273-L277 PolarHBondContact O-N 2.93Å
274	F	88.9	Confident	86.8	Confident	48 Å²	48	52.7 Å²	52.7	21%	0.211	29%	0.291	C	S	.	.	H	α-helix	trans	-65.9	-34	-176.9	-75.7	-64.2	0	0	0	113.1	V181 Y184 C270 T271 L277 M278	V181-F274 HydrophobicContact CB-CE2 4.41Å; V181-F274 HydrophobicContact CB-CZ 4.39Å; V181-F274 HydrophobicContact CG1-CZ 4.43Å; V181-F274 HydrophobicContact CG2-CD2 3.77Å; V181-F274 HydrophobicContact CG2-CE1 4.2Å; V181-F274 HydrophobicContact CG2-CE2 3.3Å; V181-F274 HydrophobicContact CG2-CG 4.42Å; V181-F274 HydrophobicContact CG2-CZ 3.55Å; Y184-F274 AromaticContact CD1-CD1 3.65Å; Y184-F274 HydrophobicContact CD1-CD1 3.65Å; Y184-F274 AromaticContact CD1-CE1 3.88Å; Y184-F274 HydrophobicContact CD1-CE1 3.88Å; Y184-F274 HydrophobicContact CE1-CD1 4.44Å; Y184-F274 HydrophobicContact CE1-CE1 4.44Å; Y184-F274 AromaticContact CG-CD1 3.76Å; Y184-F274 HydrophobicContact CG-CD1 3.76Å; Y184-F274 HydrophobicContact CG-CE1 4.45Å; C270-F274 WeakPolarHBondContact O-CD2 3.05Å; C270-F274 PolarHBondContact O-N 3.45Å; C270-F274 VanDerWaalsContact SG-CE2 3.58Å; T271-F274 PolarHBondContact O-N 3.23Å; F274-L277 HydrophobicContact CD1-CD1 4.4Å; F274-M278 WeakPolarHBondContact O-CB 3.47Å; F274-M278 PolarHBondContact O-N 2.85Å
275	Y	85.8	Confident	85.4	Confident	83 Å²	83	57.2 Å²	57.2	33%	0.325	31%	0.308	S	S	.	.	H	α-helix	trans	-68.5	-40	174.6	-173.8	-98.5	0	0	0	112	T271 I273 M278 T279 F309	T271-Y275 WeakPolarHBondContact O-CB 3.28Å; T271-Y275 PolarHBondContact O-N 2.92Å; I273-Y275 VanDerWaalsContact C-N 3.32Å; I273-Y275 PolarHBondContact O-N 3.46Å; Y275-M278 PolarHBondContact O-N 3.28Å; Y275-T279 WeakPolarHBondContact O-CB 3.41Å; Y275-T279 PolarHBondContact O-N 2.91Å; Y275-T279 PolarHBondContact O-OG1 3.48Å; Y275-F309 HydrophobicContact CD1-CD2 4.25Å; Y275-F309 HydrophobicContact CD2-CB 4.15Å; Y275-F309 HydrophobicContact CD2-CD2 4.29Å; Y275-F309 HydrophobicContact CE1-CD2 4.37Å; Y275-F309 HydrophobicContact CE2-CB 4Å; Y275-F309 HydrophobicContact CE2-CD2 4.41Å; Y275-F309 HydrophobicContact CE2-CG 4.32Å; Y275-F309 HydrophobicContact CG-CD2 4.21Å
276	T	87.1	Confident	83.8	Confident	81 Å²	81	64 Å²	64	50%	0.497	33%	0.328	S	S	.	.	H	α-helix	trans	-64.1	-49.8	174.4	-57.5	0	0	0	0	110.4	A272 I273 M278 T279 C280	A272-T276 VanDerWaalsContact O-CB 3.28Å; A272-T276 WeakPolarHBondContact O-CB 3.3Å; A272-T276 PolarHBondContact O-N 3.19Å; A272-T276 PolarHBondContact O-OG1 2.97Å; I273-T276 PolarHBondContact O-N 3.31Å; T276-M278 VanDerWaalsContact C-N 3.32Å; T276-M278 PolarHBondContact O-N 3.49Å; T276-T279 PolarHBondContact O-N 3.35Å; T276-T279 VanDerWaalsContact O-N 3.13Å; T276-C280 WeakPolarHBondContact O-CB 3.34Å; T276-C280 PolarHBondContact O-N 2.67Å; T276-C280 PolarHBondContact O-SG 2.96Å
277	L	87.3	Confident	82.1	Confident	74 Å²	74	67.2 Å²	67.2	39%	0.387	35%	0.346	S	S	.	.	H	α-helix	trans	-58.2	-43.6	176.6	-69.1	176	0	0	0	112	Y184 I273 F274 T279 C280 E281	Y184-L277 HydrophobicContact CD2-CB 3.81Å; Y184-L277 HydrophobicContact CE2-CB 3.54Å; Y184-L277 HydrophobicContact CE2-CD1 4.44Å; I273-L277 HydrophobicContact CG2-CD1 3.87Å; I273-L277 HydrophobicContact CG2-CG 4.32Å; I273-L277 WeakPolarHBondContact O-CB 3.47Å; I273-L277 VanDerWaalsContact O-CG 3.31Å; I273-L277 WeakPolarHBondContact O-CG 3.47Å; I273-L277 PolarHBondContact O-N 2.93Å; F274-L277 HydrophobicContact CD1-CD1 4.4Å; L277-T279 PolarHBondContact O-N 3.5Å; L277-C280 PolarHBondContact O-N 2.84Å; L277-E281 WeakPolarHBondContact O-CB 3.31Å; L277-E281 PolarHBondContact O-N 3.37Å
278	M	82	Confident	80.5	Confident	7 Å²	7	69.1 Å²	69.1	3%	0.034	37%	0.366	C	S	.	.	H	α-helix	trans	-60.1	-46.1	175.1	173.6	171.5	167.2	0	0	111.8	R183 Y184 V187 F274 Y275 T276 E281 M282 A305	R183-M278 HydrophobicContact CB-SD 4.4Å; Y184-M278 HydrophobicContact CD2-CB 4.29Å; V187-M278 HydrophobicContact CB-CG 4.23Å; V187-M278 HydrophobicContact CG1-CG 4.2Å; V187-M278 HydrophobicContact CG2-CE 3.55Å; V187-M278 HydrophobicContact CG2-CG 3.99Å; V187-M278 HydrophobicContact CG2-SD 3.84Å; F274-M278 WeakPolarHBondContact O-CB 3.47Å; F274-M278 PolarHBondContact O-N 2.85Å; Y275-M278 PolarHBondContact O-N 3.28Å; T276-M278 VanDerWaalsContact C-N 3.32Å; T276-M278 PolarHBondContact O-N 3.49Å; M278-E281 PolarHBondContact O-N 3.37Å; M278-M282 HydrophobicContact CE-SD 3.65Å; M278-M282 HydrophobicContact CG-SD 4.25Å; M278-M282 VanDerWaalsContact O-CG 3.27Å; M278-M282 WeakPolarHBondContact O-CG 3.46Å; M278-M282 PolarHBondContact O-N 2.84Å; M278-A305 HydrophobicContact CE-CB 3.12Å; M278-A305 HydrophobicContact SD-CB 3.32Å; M278-A305 WeakPolarHBondContact SD-CB 3.42Å
279	T	80.6	Confident	78.6	Confident	52 Å²	52	73.2 Å²	73.2	32%	0.319	40%	0.398	S	S	.	.	H	α-helix	trans	-65.8	-42.7	-179.8	-58.3	0	0	0	0	111.2	Y275 T276 L277 M282 L283	Y275-T279 WeakPolarHBondContact O-CB 3.41Å; Y275-T279 PolarHBondContact O-N 2.91Å; Y275-T279 PolarHBondContact O-OG1 3.48Å; T276-T279 PolarHBondContact O-N 3.35Å; T276-T279 VanDerWaalsContact O-N 3.13Å; L277-T279 PolarHBondContact O-N 3.5Å; T279-M282 PolarHBondContact O-N 3.2Å; T279-L283 HydrophobicContact CG2-CD1 3.99Å; T279-L283 HydrophobicContact CG2-CG 4.46Å; T279-L283 WeakPolarHBondContact O-CB 3.13Å; T279-L283 VanDerWaalsContact O-CG 3.28Å; T279-L283 WeakPolarHBondContact O-CG 3.39Å; T279-L283 PolarHBondContact O-N 3.48Å
280	C	83.4	Confident	76.7	Confident	68 Å²	68	74.9 Å²	74.9	46%	0.459	40%	0.404	S	S	.	.	H	α-helix	trans	-60.8	-47	175.3	-69.9	0	0	0	0	111.7	T276 L277 M282 L283 N284	T276-C280 WeakPolarHBondContact O-CB 3.34Å; T276-C280 PolarHBondContact O-N 2.67Å; T276-C280 PolarHBondContact O-SG 2.96Å; L277-C280 PolarHBondContact O-N 2.84Å; C280-M282 VanDerWaalsContact C-N 3.31Å; C280-M282 PolarHBondContact O-N 2.92Å; C280-L283 PolarHBondContact O-N 3.44Å; C280-N284 WeakPolarHBondContact O-CB 3.15Å; C280-N284 PolarHBondContact O-N 3.34Å
281	E	80.4	Confident	75	Confident	47 Å²	47	85 Å²	85	22%	0.22	44%	0.44	C	S	.	.	H	α-helix	trans	-60.6	-41.2	178.1	-175.6	61.4	-161.9	0	0	111.5	V187 L277 M278 R285	V187-E281 HydrophobicContact CG1-CG 4.37Å; L277-E281 WeakPolarHBondContact O-CB 3.31Å; L277-E281 PolarHBondContact O-N 3.37Å; M278-E281 PolarHBondContact O-N 3.37Å; E281-R285 WeakPolarHBondContact O-CG 3.5Å; E281-R285 PolarHBondContact O-N 3.25Å; E281-R285 IonicContact OE1-CZ 3.82Å; E281-R285 IonicContact OE1-NE 2.75Å; E281-R285 PolarHBondContact OE1-NE 3.3Å; E281-R285 IonicContact OE1-NH2 3.01Å; E281-R285 PolarHBondContact OE1-NH2 3.22Å
282	M	72	Confident	73.3	Confident	35 Å²	35	91.3 Å²	91.3	17%	0.172	47%	0.472	C	S	.	.	H	α-helix	trans	-66.1	-39.5	175.5	-71.3	-178.1	70.4	0	0	112.8	V187 M278 T279 C280 R286 L298 R302	V187-M282 HydrophobicContact CG1-CG 3.72Å; V187-M282 HydrophobicContact CG1-SD 4.48Å; M278-M282 HydrophobicContact CE-SD 3.65Å; M278-M282 HydrophobicContact CG-SD 4.25Å; M278-M282 VanDerWaalsContact O-CG 3.27Å; M278-M282 WeakPolarHBondContact O-CG 3.46Å; M278-M282 PolarHBondContact O-N 2.84Å; T279-M282 PolarHBondContact O-N 3.2Å; C280-M282 VanDerWaalsContact C-N 3.31Å; C280-M282 PolarHBondContact O-N 2.92Å; M282-R286 PolarHBondContact O-N 3.16Å; M282-L298 HydrophobicContact CE-CB 4.17Å; M282-L298 HydrophobicContact CE-CD2 4.3Å; M282-R302 HydrophobicContact CE-CB 4.29Å
283	L	74.1	Confident	71.5	Confident	77 Å²	77	93.2 Å²	93.2	40%	0.403	49%	0.487	S	S	.	.	H	α-helix	trans	-70.6	-40.3	178.7	-74.1	170.4	0	0	0	112.1	T279 C280 R285 R286	T279-L283 HydrophobicContact CG2-CD1 3.99Å; T279-L283 HydrophobicContact CG2-CG 4.46Å; T279-L283 WeakPolarHBondContact O-CB 3.13Å; T279-L283 VanDerWaalsContact O-CG 3.28Å; T279-L283 WeakPolarHBondContact O-CG 3.39Å; T279-L283 PolarHBondContact O-N 3.48Å; C280-L283 PolarHBondContact O-N 3.44Å; L283-R285 VanDerWaalsContact C-N 3.32Å; L283-R285 PolarHBondContact O-N 3.24Å; L283-R286 VanDerWaalsContact O-CB 3.3Å; L283-R286 WeakPolarHBondContact O-CB 3.39Å; L283-R286 PolarHBondContact O-N 3.27Å; L283-R286 VanDerWaalsContact O-N 3.15Å
284	N	74.8	Confident	69.7	Low	116 Å²	116	90.1 Å²	90.1	62%	0.62	47%	0.471	S	S	*	.	H	α-helix	trans	-63.3	-40.8	178.2	-161.9	20.3	0	0	0	110.9	C280 R286 N287	C280-N284 WeakPolarHBondContact O-CB 3.15Å; C280-N284 PolarHBondContact O-N 3.34Å; N284-R286 VanDerWaalsContact C-N 3.31Å; N284-R286 PolarHBondContact O-N 3.36Å; N284-N287 PolarHBondContact O-N 3.2Å
285	R	65.9	Low	68.3	Low	111 Å²	111	90.5 Å²	90.5	42%	0.419	48%	0.48	S	S	.	.	H	α-helix	trans	-72.2	-20.4	175.5	-66.9	-171.1	-171.8	-131.6	3.8	114.2	A188 E281 L283 N287 G288	A188-R285 PolarHBondContact O-NH2 2.91Å; E281-R285 WeakPolarHBondContact O-CG 3.5Å; E281-R285 PolarHBondContact O-N 3.25Å; E281-R285 IonicContact OE1-CZ 3.82Å; E281-R285 IonicContact OE1-NE 2.75Å; E281-R285 PolarHBondContact OE1-NE 3.3Å; E281-R285 IonicContact OE1-NH2 3.01Å; E281-R285 PolarHBondContact OE1-NH2 3.22Å; L283-R285 VanDerWaalsContact C-N 3.32Å; L283-R285 PolarHBondContact O-N 3.24Å; R285-N287 PolarHBondContact O-N 2.9Å; R285-G288 PolarHBondContact O-N 2.88Å
286	R	61.5	Low	67	Low	182 Å²	182	91.6 Å²	91.6	69%	0.687	49%	0.488	S	S	*	.	H	α-helix	trans	-67.5	-24.8	172.7	-169.8	177.2	69.3	170	1.7	112.5	M282 L283 N284 G288	M282-R286 PolarHBondContact O-N 3.16Å; L283-R286 VanDerWaalsContact O-CB 3.3Å; L283-R286 WeakPolarHBondContact O-CB 3.39Å; L283-R286 PolarHBondContact O-N 3.27Å; L283-R286 VanDerWaalsContact O-N 3.15Å; N284-R286 VanDerWaalsContact C-N 3.31Å; N284-R286 PolarHBondContact O-N 3.36Å; R286-G288 VanDerWaalsContact C-N 3.31Å
287	N	57	Low	65.8	Low	139 Å²	139	93.5 Å²	93.5	74%	0.743	49%	0.491	S	S	*	.	T	Hydrogen-bonded Turn	trans	-82.1	-6	175.7	-72.3	-8.2	0	0	0	113.2	N284 R285	N284-N287 PolarHBondContact O-N 3.2Å; R285-N287 PolarHBondContact O-N 2.9Å
288	G	59.7	Low	64.7	Low	41 Å²	41	91.6 Å²	91.6	42%	0.423	48%	0.481	S	S	.	.	S	Bend	trans	-92.2	149.4	172.7	0	0	0	0	0	113.4	R285 R286 L290	R285-G288 PolarHBondContact O-N 2.88Å; R286-G288 VanDerWaalsContact C-N 3.31Å; G288-L290 PolarHBondContact O-N 3.24Å
289	S	51.6	Low	63.9	Low	131 Å²	131	96.8 Å²	96.8	92%	0.916	50%	0.504	S	S	*	.	S	Bend	trans	-68.6	46.2	-173.4	-176.8	0	0	0	0	116.4
290	L	55.3	Low	63.1	Low	116 Å²	116	100.5 Å²	100.5	61%	0.607	52%	0.517	S	S	*	.			trans	-128.8	73.5	176.8	-157.1	70	0	0	0	111.2	G288 L294	G288-L290 PolarHBondContact O-N 3.24Å; L290-L294 HydrophobicContact CB-CD2 4.43Å; L290-L294 HydrophobicContact CD2-CD2 4.29Å
291	R	55.7	Low	62.2	Low	229 Å²	229	100.4 Å²	100.4	86%	0.864	51%	0.507	S	S	*	.			trans	-90.9	-13.9	-151.5	-131.3	178.6	-174.2	-166.1	1.4	117.2
292	I	54	Low	61.6	Low	142 Å²	142	106 Å²	106	73%	0.728	53%	0.526	S	S	*	.	S	Bend	trans	-128.1	-55.7	-162.9	-51.9	179.4	0	0	0	114	L294 S295	I292-L294 PolarHBondContact O-N 2.84Å; I292-S295 WeakPolarHBondContact O-CB 3.46Å; I292-S295 PolarHBondContact O-N 3.43Å; I292-S295 PolarHBondContact O-OG 3.01Å
293	A	51.7	Low	61.4	Low	89 Å²	89	108.5 Å²	108.5	74%	0.736	54%	0.538	S	S	*	.	H	α-helix	trans	-74.2	-26.2	179.7	0	0	0	0	0	114	S295	A293-S295 PolarHBondContact O-N 2.84Å
294	L	55.4	Low	61.1	Low	24 Å²	24	107.5 Å²	107.5	13%	0.126	54%	0.535	C	S	.	.	H	α-helix	trans	-70.2	-22.5	176.7	-173.7	64.4	0	0	0	112	W190 L290 I292 L298	W190-L294 HydrophobicContact CZ2-CD1 3.65Å; L290-L294 HydrophobicContact CB-CD2 4.43Å; L290-L294 HydrophobicContact CD2-CD2 4.29Å; I292-L294 PolarHBondContact O-N 2.84Å; L294-L298 HydrophobicContact CD1-CD1 4.33Å; L294-L298 HydrophobicContact CD1-CG 4.15Å; L294-L298 HydrophobicContact CD2-CD1 3.9Å; L294-L298 HydrophobicContact CG-CD1 3.6Å; L294-L298 HydrophobicContact CG-CG 3.88Å; L294-L298 VanDerWaalsContact O-CB 3.28Å; L294-L298 WeakPolarHBondContact O-CB 3.47Å; L294-L298 WeakPolarHBondContact O-CG 3.49Å; L294-L298 PolarHBondContact O-N 3.49Å
295	S	58.5	Low	60.8	Low	56 Å²	56	102.2 Å²	102.2	39%	0.392	51%	0.507	S	S	.	.	H	α-helix	trans	-65.9	-42	-173.6	71.3	0	0	0	0	113.3	I292 A293 L298 K299	I292-S295 WeakPolarHBondContact O-CB 3.46Å; I292-S295 PolarHBondContact O-N 3.43Å; I292-S295 PolarHBondContact O-OG 3.01Å; A293-S295 PolarHBondContact O-N 2.84Å; S295-L298 PolarHBondContact O-N 2.74Å; S295-K299 WeakPolarHBondContact O-CB 3.5Å; S295-K299 PolarHBondContact O-N 2.96Å
296	E	58.5	Low	61.2	Low	106 Å²	106	101.6 Å²	101.6	50%	0.495	51%	0.507	S	S	.	.	H	α-helix	trans	-73.1	-39.1	-178.8	-77.9	-63.8	138.2	0	0	112.3	K299 Q300	E296-K299 PolarHBondContact O-N 2.94Å; E296-K299 IonicContact OE1-NZ 3.96Å; E296-K299 PolarHBondContact OE1-NZ 3.47Å; E296-K299 IonicContact OE2-NZ 3.42Å; E296-Q300 PolarHBondContact O-N 3.37Å
297	H	62.1	Low	61.7	Low	121 Å²	121	93.4 Å²	93.4	56%	0.56	48%	0.477	S	S	*	.	H	α-helix	trans	-67.6	-37.9	172.2	-79.7	-70.8	0	0	0	112.5	R301	H297-R301 VanDerWaalsContact O-CG 3.3Å; H297-R301 WeakPolarHBondContact O-CG 3.25Å; H297-R301 PolarHBondContact O-N 2.86Å
298	L	63.6	Low	62.5	Low	35 Å²	35	87.4 Å²	87.4	18%	0.183	45%	0.446	C	S	.	.	H	α-helix	trans	-68.4	-35	173.4	-73.6	179	0	0	0	112.2	M282 L294 S295 R301 R302	M282-L298 HydrophobicContact CE-CB 4.17Å; M282-L298 HydrophobicContact CE-CD2 4.3Å; L294-L298 HydrophobicContact CD1-CD1 4.33Å; L294-L298 HydrophobicContact CD1-CG 4.15Å; L294-L298 HydrophobicContact CD2-CD1 3.9Å; L294-L298 HydrophobicContact CG-CD1 3.6Å; L294-L298 HydrophobicContact CG-CG 3.88Å; L294-L298 VanDerWaalsContact O-CB 3.28Å; L294-L298 WeakPolarHBondContact O-CB 3.47Å; L294-L298 WeakPolarHBondContact O-CG 3.49Å; L294-L298 PolarHBondContact O-N 3.49Å; S295-L298 PolarHBondContact O-N 2.74Å; L298-R301 PolarHBondContact O-N 3.24Å; L298-R302 WeakPolarHBondContact O-CB 3.4Å; L298-R302 PolarHBondContact O-N 3.04Å
299	K	66	Low	63.5	Low	116 Å²	116	90 Å²	90	50%	0.504	45%	0.446	S	S	.	.	H	α-helix	trans	-64.7	-45	174.7	-173.1	-179.8	179.1	-174.6	0	111.2	S295 E296 R301 R302 E303	S295-K299 WeakPolarHBondContact O-CB 3.5Å; S295-K299 PolarHBondContact O-N 2.96Å; E296-K299 PolarHBondContact O-N 2.94Å; E296-K299 IonicContact OE1-NZ 3.96Å; E296-K299 PolarHBondContact OE1-NZ 3.47Å; E296-K299 IonicContact OE2-NZ 3.42Å; K299-R301 VanDerWaalsContact C-N 3.34Å; K299-R301 PolarHBondContact O-N 3.31Å; K299-R302 WeakPolarHBondContact O-CB 3.41Å; K299-R302 PolarHBondContact O-N 3.11Å; K299-E303 WeakPolarHBondContact O-CG 3.42Å; K299-E303 PolarHBondContact O-N 3.28Å
300	Q	63.4	Low	64.9	Low	129 Å²	129	85 Å²	85	60%	0.603	41%	0.411	S	S	*	.	H	α-helix	trans	-58.7	-43.7	170.7	-80.2	-173	-28.8	0	0	112.1	E296 R302 E303 V304	E296-Q300 PolarHBondContact O-N 3.37Å; Q300-R302 VanDerWaalsContact C-N 3.33Å; Q300-R302 PolarHBondContact O-N 3.45Å; Q300-E303 PolarHBondContact O-N 2.98Å; Q300-V304 WeakPolarHBondContact O-CG2 2.98Å; Q300-V304 PolarHBondContact O-N 3.33Å
301	R	65.4	Low	66.2	Low	66 Å²	66	79.7 Å²	79.7	25%	0.249	38%	0.383	C	S	.	.	H	α-helix	trans	-63.7	-36.8	177	-71.1	173	-177.6	-151	-5.3	112.4	A186 V187 H297 L298 K299 V304 A305	A186-R301 VanDerWaalsContact O-CZ 3.27Å; A186-R301 PolarHBondContact O-NH1 2.9Å; V187-R301 HydrophobicContact CG2-CB 4.3Å; H297-R301 VanDerWaalsContact O-CG 3.3Å; H297-R301 WeakPolarHBondContact O-CG 3.25Å; H297-R301 PolarHBondContact O-N 2.86Å; L298-R301 PolarHBondContact O-N 3.24Å; K299-R301 VanDerWaalsContact C-N 3.34Å; K299-R301 PolarHBondContact O-N 3.31Å; R301-V304 PolarHBondContact O-N 2.98Å; R301-A305 PolarHBondContact O-N 2.72Å
302	R	66.5	Low	67.6	Low	165 Å²	165	69.1 Å²	69.1	62%	0.623	34%	0.344	S	S	*	.	H	α-helix	trans	-64.3	-44.4	175.4	-169.1	178.7	-176.9	-178.1	-0.1	112.3	M282 L298 K299 Q300 V304 A305 K306	M282-R302 HydrophobicContact CE-CB 4.29Å; L298-R302 WeakPolarHBondContact O-CB 3.4Å; L298-R302 PolarHBondContact O-N 3.04Å; K299-R302 WeakPolarHBondContact O-CB 3.41Å; K299-R302 PolarHBondContact O-N 3.11Å; Q300-R302 VanDerWaalsContact C-N 3.33Å; Q300-R302 PolarHBondContact O-N 3.45Å; R302-V304 VanDerWaalsContact C-N 3.3Å; R302-V304 PolarHBondContact O-N 3.29Å; R302-A305 PolarHBondContact O-N 3.27Å; R302-K306 VanDerWaalsContact O-CB 3.29Å; R302-K306 WeakPolarHBondContact O-CB 3.32Å; R302-K306 PolarHBondContact O-N 3.3Å
303	E	69	Low	69.2	Low	88 Å²	88	64.9 Å²	64.9	41%	0.411	32%	0.324	S	S	.	.	H	α-helix	trans	-61.4	-40.1	177.4	-70.8	-58.7	136.2	0	0	111.6	K299 Q300 K306 T307	K299-E303 WeakPolarHBondContact O-CG 3.42Å; K299-E303 PolarHBondContact O-N 3.28Å; Q300-E303 PolarHBondContact O-N 2.98Å; E303-K306 PolarHBondContact O-N 3.39Å; E303-T307 PolarHBondContact O-N 2.83Å; E303-T307 PolarHBondContact O-OG1 2.79Å
304	V	66.6	Low	70.8	Confident	56 Å²	56	60.7 Å²	60.7	34%	0.339	29%	0.29	S	S	.	.	H	α-helix	trans	-72	-36.1	178.4	-171.3	0	0	0	0	112	Q300 R301 R302 T307 V308	Q300-V304 WeakPolarHBondContact O-CG2 2.98Å; Q300-V304 PolarHBondContact O-N 3.33Å; R301-V304 PolarHBondContact O-N 2.98Å; R302-V304 VanDerWaalsContact C-N 3.3Å; R302-V304 PolarHBondContact O-N 3.29Å; V304-T307 WeakPolarHBondContact O-CB 3.45Å; V304-T307 PolarHBondContact O-N 3.5Å; V304-V308 PolarHBondContact O-N 3.34Å
305	A	69.6	Low	72.4	Confident	5 Å²	5	59.6 Å²	59.6	4%	0.041	28%	0.284	C	S	.	.	H	α-helix	trans	-71.5	-35.1	173.8	0	0	0	0	0	113.5	M278 R301 R302 T307 V308 F309	M278-A305 HydrophobicContact CE-CB 3.12Å; M278-A305 HydrophobicContact SD-CB 3.32Å; M278-A305 WeakPolarHBondContact SD-CB 3.42Å; R301-A305 PolarHBondContact O-N 2.72Å; R302-A305 PolarHBondContact O-N 3.27Å; A305-T307 PolarHBondContact O-N 3.46Å; A305-V308 PolarHBondContact O-N 3.35Å; A305-V308 VanDerWaalsContact O-N 3.13Å; A305-F309 PolarHBondContact O-N 3.29Å
306	K	73.5	Confident	73.9	Confident	98 Å²	98	58 Å²	58	43%	0.426	27%	0.274	S	S	.	.	H	α-helix	trans	-58.9	-34.7	169.3	-176.9	-179.3	177.1	-177.9	0	111.3	R302 E303 C310	R302-K306 VanDerWaalsContact O-CB 3.29Å; R302-K306 WeakPolarHBondContact O-CB 3.32Å; R302-K306 PolarHBondContact O-N 3.3Å; E303-K306 PolarHBondContact O-N 3.39Å; K306-C310 VanDerWaalsContact O-CB 3.25Å; K306-C310 WeakPolarHBondContact O-CB 3.2Å; K306-C310 PolarHBondContact O-N 3.02Å
307	T	73.2	Confident	75.4	Confident	9 Å²	9	57.5 Å²	57.5	6%	0.055	27%	0.274	C	S	.	.	H	α-helix	trans	-60.3	-50.7	171.9	-47.6	0	0	0	0	111.4	E303 V304 A305 C310 L311 L369 V372	E303-T307 PolarHBondContact O-N 2.83Å; E303-T307 PolarHBondContact O-OG1 2.79Å; V304-T307 WeakPolarHBondContact O-CB 3.45Å; V304-T307 PolarHBondContact O-N 3.5Å; A305-T307 PolarHBondContact O-N 3.46Å; T307-C310 WeakPolarHBondContact O-CB 3.32Å; T307-C310 PolarHBondContact O-N 3.49Å; T307-L311 HydrophobicContact CG2-CD1 4.4Å; T307-L311 WeakPolarHBondContact O-CG 2.92Å; T307-L311 PolarHBondContact O-N 2.81Å; T307-L369 HydrophobicContact CG2-CD2 3.98Å; T307-V372 HydrophobicContact CG2-CB 3.85Å; T307-V372 HydrophobicContact CG2-CG1 4.02Å; T307-V372 HydrophobicContact CG2-CG2 4.49Å; T307-V372 WeakPolarHBondContact OG1-CG1 3.23Å
308	V	74	Confident	76.7	Confident	14 Å²	14	52 Å²	52	9%	0.085	25%	0.25	C	C	.	.	H	α-helix	trans	-64.6	-43	-179.3	178.8	0	0	0	0	111.4	L179 S180 R183 V304 A305 C310 L311 V312	L179-V308 HydrophobicContact CB-CG1 4.37Å; L179-V308 HydrophobicContact CB-CG2 4.45Å; S180-V308 VanDerWaalsContact OG-CG1 3.31Å; S180-V308 WeakPolarHBondContact OG-CG1 3.26Å; R183-V308 HydrophobicContact CG-CB 4.22Å; R183-V308 HydrophobicContact CG-CG2 3.57Å; V304-V308 PolarHBondContact O-N 3.34Å; A305-V308 PolarHBondContact O-N 3.35Å; A305-V308 VanDerWaalsContact O-N 3.13Å; V308-C310 VanDerWaalsContact C-N 3.33Å; V308-C310 PolarHBondContact O-N 2.78Å; V308-L311 WeakPolarHBondContact O-CB 2.88Å; V308-L311 PolarHBondContact O-N 3.11Å; V308-V312 VanDerWaalsContact O-CG2 3.28Å; V308-V312 WeakPolarHBondContact O-CG2 3.18Å; V308-V312 PolarHBondContact O-N 3.35Å; V308-V312 VanDerWaalsContact O-N 3.08Å
309	F	79.3	Confident	77.9	Confident	94 Å²	94	50.9 Å²	50.9	41%	0.412	24%	0.243	S	C	.	.	H	α-helix	trans	-59.3	-43.2	173.9	-178.9	-97.1	0	0	0	112.1	Y275 A305 L311 V312 V313	Y275-F309 HydrophobicContact CD1-CD2 4.25Å; Y275-F309 HydrophobicContact CD2-CB 4.15Å; Y275-F309 HydrophobicContact CD2-CD2 4.29Å; Y275-F309 HydrophobicContact CE1-CD2 4.37Å; Y275-F309 HydrophobicContact CE2-CB 4Å; Y275-F309 HydrophobicContact CE2-CD2 4.41Å; Y275-F309 HydrophobicContact CE2-CG 4.32Å; Y275-F309 HydrophobicContact CG-CD2 4.21Å; A305-F309 PolarHBondContact O-N 3.29Å; F309-L311 PolarHBondContact O-N 3.13Å; F309-V312 PolarHBondContact O-N 3.25Å; F309-V313 HydrophobicContact CD1-CG2 4.12Å; F309-V313 HydrophobicContact CE1-CG2 3.66Å; F309-V313 HydrophobicContact CE2-CG2 4.38Å; F309-V313 HydrophobicContact CZ-CG2 3.81Å; F309-V313 WeakPolarHBondContact O-CG2 3.27Å; F309-V313 PolarHBondContact O-N 3.33Å
310	C	82.4	Confident	79.1	Confident	27 Å²	27	50.1 Å²	50.1	18%	0.182	24%	0.239	C	C	.	.	H	α-helix	trans	-60.8	-43.7	176.2	-169.7	0	0	0	0	112	K306 T307 V308 V312 V313 I314	K306-C310 VanDerWaalsContact O-CB 3.25Å; K306-C310 WeakPolarHBondContact O-CB 3.2Å; K306-C310 PolarHBondContact O-N 3.02Å; T307-C310 WeakPolarHBondContact O-CB 3.32Å; T307-C310 PolarHBondContact O-N 3.49Å; V308-C310 VanDerWaalsContact C-N 3.33Å; V308-C310 PolarHBondContact O-N 2.78Å; C310-V312 VanDerWaalsContact C-N 3.27Å; C310-V312 PolarHBondContact O-N 2.86Å; C310-V313 PolarHBondContact O-N 2.7Å; C310-I314 WeakPolarHBondContact O-CD1 3Å; C310-I314 VanDerWaalsContact O-CG1 3.3Å; C310-I314 WeakPolarHBondContact O-CG1 3.47Å; C310-I314 PolarHBondContact O-N 2.7Å
311	L	82.4	Confident	80.3	Confident	5 Å²	5	45.4 Å²	45.4	3%	0.026	22%	0.22	C	C	.	.	H	α-helix	trans	-60.1	-37.7	176.6	-70	172.1	0	0	0	112	L176 T307 V308 F309 I314 F315 A368 L369	L176-L311 HydrophobicContact CD2-CB 4.03Å; T307-L311 HydrophobicContact CG2-CD1 4.4Å; T307-L311 WeakPolarHBondContact O-CG 2.92Å; T307-L311 PolarHBondContact O-N 2.81Å; V308-L311 WeakPolarHBondContact O-CB 2.88Å; V308-L311 PolarHBondContact O-N 3.11Å; F309-L311 PolarHBondContact O-N 3.13Å; L311-I314 WeakPolarHBondContact O-CB 3.04Å; L311-F315 WeakPolarHBondContact O-CB 3.47Å; L311-F315 PolarHBondContact O-N 3.02Å; L311-A368 HydrophobicContact CD2-CB 3.54Å; L311-L369 HydrophobicContact CD1-CD2 4.39Å
312	V	85.1	Confident	81.4	Confident	7 Å²	7	42.6 Å²	42.6	4%	0.042	21%	0.21	C	C	.	.	H	α-helix	trans	-70.9	-40.9	177.4	174.3	0	0	0	0	111.8	L268 T271 V308 F309 C310 I314 F315 A316	L268-V312 HydrophobicContact CD2-CG1 3.64Å; T271-V312 HydrophobicContact CG2-CB 4.32Å; T271-V312 HydrophobicContact CG2-CG1 4.08Å; T271-V312 HydrophobicContact CG2-CG2 3.28Å; T271-V312 VanDerWaalsContact OG1-CG1 3.3Å; T271-V312 WeakPolarHBondContact OG1-CG1 3.45Å; V308-V312 VanDerWaalsContact O-CG2 3.28Å; V308-V312 WeakPolarHBondContact O-CG2 3.18Å; V308-V312 PolarHBondContact O-N 3.35Å; V308-V312 VanDerWaalsContact O-N 3.08Å; F309-V312 PolarHBondContact O-N 3.25Å; C310-V312 VanDerWaalsContact C-N 3.27Å; C310-V312 PolarHBondContact O-N 2.86Å; V312-I314 VanDerWaalsContact C-N 3.34Å; V312-F315 WeakPolarHBondContact O-CB 3.27Å; V312-F315 PolarHBondContact O-N 3.43Å; V312-A316 WeakPolarHBondContact O-CB 3.37Å; V312-A316 PolarHBondContact O-N 3.42Å
313	V	86.7	Confident	82.5	Confident	52 Å²	52	35 Å²	35	32%	0.315	18%	0.182	S	C	.	.	H	α-helix	trans	-64.3	-42.3	176.1	171.7	0	0	0	0	110.5	F309 C310 F315 A316 L317	F309-V313 HydrophobicContact CD1-CG2 4.12Å; F309-V313 HydrophobicContact CE1-CG2 3.66Å; F309-V313 HydrophobicContact CE2-CG2 4.38Å; F309-V313 HydrophobicContact CZ-CG2 3.81Å; F309-V313 WeakPolarHBondContact O-CG2 3.27Å; F309-V313 PolarHBondContact O-N 3.33Å; C310-V313 PolarHBondContact O-N 2.7Å; V313-F315 VanDerWaalsContact C-N 3.33Å; V313-F315 PolarHBondContact O-N 2.82Å; V313-A316 WeakPolarHBondContact O-CB 3.25Å; V313-A316 PolarHBondContact O-N 3.46Å; V313-L317 HydrophobicContact CG1-CD1 4.03Å; V313-L317 HydrophobicContact CG1-CG 4.4Å; V313-L317 WeakPolarHBondContact O-CG 3.28Å; V313-L317 PolarHBondContact O-N 3.42Å
314	I	86.3	Confident	83.5	Confident	2 Å²	2	34.2 Å²	34.2	1%	0.01	18%	0.18	C	C	.	.	H	α-helix	trans	-54.8	-52.2	171.5	-74.4	155.1	0	0	0	110.2	F4 C310 L311 V312 A316 L317 C318 I364 A368	F4-I314 HydrophobicContact CE1-CG1 4.07Å; F4-I314 HydrophobicContact CE2-CD1 3.59Å; F4-I314 HydrophobicContact CE2-CG1 3.53Å; F4-I314 HydrophobicContact CZ-CB 4.46Å; F4-I314 HydrophobicContact CZ-CD1 3.7Å; F4-I314 HydrophobicContact CZ-CG1 3.13Å; C310-I314 WeakPolarHBondContact O-CD1 3Å; C310-I314 VanDerWaalsContact O-CG1 3.3Å; C310-I314 WeakPolarHBondContact O-CG1 3.47Å; C310-I314 PolarHBondContact O-N 2.7Å; L311-I314 WeakPolarHBondContact O-CB 3.04Å; V312-I314 VanDerWaalsContact C-N 3.34Å; I314-A316 VanDerWaalsContact C-N 3.32Å; I314-A316 PolarHBondContact O-N 3.48Å; I314-L317 PolarHBondContact O-N 3.3Å; I314-C318 WeakPolarHBondContact O-CB 3.28Å; I314-C318 PolarHBondContact O-N 2.81Å; I314-C318 PolarHBondContact O-SG 3.3Å; I314-I364 HydrophobicContact CB-CG2 4.45Å; I314-I364 HydrophobicContact CD1-CG2 3.8Å; I314-I364 HydrophobicContact CG1-CG2 4.1Å; I314-I364 HydrophobicContact CG2-CB 4.04Å; I314-I364 HydrophobicContact CG2-CD1 4.15Å; I314-I364 HydrophobicContact CG2-CG2 3.51Å; I314-A368 HydrophobicContact CD1-CB 3.65Å
315	F	88.4	Confident	84.4	Confident	0 Å²	0	31.7 Å²	31.7	0%	0	17%	0.165	C	C	.	.	H	α-helix	trans	-55.2	-48.1	177.9	170.2	-92.1	0	0	0	111.1	T172 V173 L176 Y263 F264 P267 L311 V312 V313 L317 C318 W319 N361	T172-F315 HydrophobicContact CG2-CD2 4.46Å; V173-F315 HydrophobicContact CG1-CE1 4.38Å; V173-F315 HydrophobicContact CG1-CE2 3.55Å; V173-F315 HydrophobicContact CG1-CZ 3.47Å; V173-F315 VanDerWaalsContact CG1-CZ 3.47Å; L176-F315 HydrophobicContact CD1-CB 3.93Å; L176-F315 HydrophobicContact CD1-CD2 4.02Å; L176-F315 HydrophobicContact CD1-CG 3.88Å; Y263-F315 VanDerWaalsContact O-CZ 3.22Å; Y263-F315 WeakPolarHBondContact O-CZ 3.29Å; F264-F315 HydrophobicContact CD2-CE1 4.31Å; P267-F315 HydrophobicContact CG-CE1 3.81Å; P267-F315 HydrophobicContact CG-CZ 4.27Å; L311-F315 WeakPolarHBondContact O-CB 3.47Å; L311-F315 PolarHBondContact O-N 3.02Å; V312-F315 WeakPolarHBondContact O-CB 3.27Å; V312-F315 PolarHBondContact O-N 3.43Å; V313-F315 VanDerWaalsContact C-N 3.33Å; V313-F315 PolarHBondContact O-N 2.82Å; F315-L317 PolarHBondContact O-N 2.9Å; F315-C318 PolarHBondContact O-N 3.27Å; F315-W319 AromaticContact CD2-CD1 3.27Å; F315-W319 HydrophobicContact CD2-CG 4.07Å; F315-W319 AromaticContact CD2-NE1 3.53Å; F315-W319 HydrophobicContact CE2-CB 4.41Å; F315-W319 AromaticContact CE2-CD1 3.23Å; F315-W319 AromaticContact CE2-CD2 4Å; F315-W319 HydrophobicContact CE2-CD2 4Å; F315-W319 AromaticContact CE2-CE2 3.94Å; F315-W319 AromaticContact CE2-CG 3.61Å; F315-W319 HydrophobicContact CE2-CG 3.61Å; F315-W319 AromaticContact CE2-NE1 3.39Å; F315-W319 HydrophobicContact CZ-CB 4.25Å; F315-W319 AromaticContact CZ-CD1 3.92Å; F315-W319 HydrophobicContact CZ-CD2 4.38Å; F315-W319 AromaticContact CZ-CG 3.89Å; F315-W319 HydrophobicContact CZ-CG 3.89Å; F315-W319 WeakPolarHBondContact O-CB 3.47Å; F315-W319 PolarHBondContact O-N 3.29Å; F315-N361 WeakPolarHBondContact CA-OD1 3.37Å
316	A	89.8	Confident	85.3	Confident	22 Å²	22	33.8 Å²	33.8	18%	0.182	17%	0.172	C	C	.	.	H	α-helix	trans	-57.2	-50.2	178.4	0	0	0	0	0	111.8	L268 V312 V313 I314 C318 W319 F320	L268-A316 HydrophobicContact CD1-CB 4.4Å; L268-A316 HydrophobicContact CD2-CB 3.73Å; V312-A316 WeakPolarHBondContact O-CB 3.37Å; V312-A316 PolarHBondContact O-N 3.42Å; V313-A316 WeakPolarHBondContact O-CB 3.25Å; V313-A316 PolarHBondContact O-N 3.46Å; I314-A316 VanDerWaalsContact C-N 3.32Å; I314-A316 PolarHBondContact O-N 3.48Å; A316-C318 VanDerWaalsContact C-N 3.33Å; A316-C318 PolarHBondContact O-N 3.18Å; A316-W319 PolarHBondContact O-N 3.46Å; A316-F320 WeakPolarHBondContact O-CB 3.28Å; A316-F320 PolarHBondContact O-N 3.22Å
317	L	89.3	Confident	86	Confident	96 Å²	96	30.3 Å²	30.3	50%	0.503	16%	0.157	S	C	.	.	H	α-helix	trans	-64.7	-37.4	-178.6	-68	173.9	0	0	0	112.2	V313 I314 F315 P321 L357	V313-L317 HydrophobicContact CG1-CD1 4.03Å; V313-L317 HydrophobicContact CG1-CG 4.4Å; V313-L317 WeakPolarHBondContact O-CG 3.28Å; V313-L317 PolarHBondContact O-N 3.42Å; I314-L317 PolarHBondContact O-N 3.3Å; F315-L317 PolarHBondContact O-N 2.9Å; L317-P321 VanDerWaalsContact O-CD 3.27Å; L317-P321 WeakPolarHBondContact O-CD 3.28Å; L317-L357 VanDerWaalsContact O-CD2 3.28Å; L317-L357 WeakPolarHBondContact O-CD2 3.41Å
318	C	89.8	Confident	86.6	Confident	7 Å²	7	32.8 Å²	32.8	5%	0.047	17%	0.17	C	C	.	.	H	α-helix	trans	-73.2	-38.3	-179.4	-66.6	0	0	0	0	112.7	I314 F315 A316 L357 A358 N361	I314-C318 WeakPolarHBondContact O-CB 3.28Å; I314-C318 PolarHBondContact O-N 2.81Å; I314-C318 PolarHBondContact O-SG 3.3Å; F315-C318 PolarHBondContact O-N 3.27Å; A316-C318 VanDerWaalsContact C-N 3.33Å; A316-C318 PolarHBondContact O-N 3.18Å; C318-L357 WeakPolarHBondContact CB-O 3.41Å; C318-L357 CarbonylContact O-C 3.59Å; C318-A358 PolarHBondContact O-N 3.24Å; C318-N361 HydrophobicContact CB-CB 3.92Å
319	W	89.8	Confident	87	Confident	11 Å²	11	35.3 Å²	35.3	4%	0.042	18%	0.18	C	C	.	.	H	α-helix	trans	-92.4	-25.1	-173.6	-76	83.3	0	0	0	113.7	V169 F264 F315 A316 L322 H323 A358 N361	V169-W319 HydrophobicContact CB-CH2 4.03Å; V169-W319 HydrophobicContact CB-CZ2 4.37Å; V169-W319 HydrophobicContact CG1-CE3 4.3Å; V169-W319 HydrophobicContact CG1-CH2 3.58Å; V169-W319 HydrophobicContact CG1-CZ2 3.81Å; V169-W319 HydrophobicContact CG1-CZ3 3.8Å; V169-W319 HydrophobicContact CG2-CH2 3.11Å; V169-W319 HydrophobicContact CG2-CZ2 3.67Å; V169-W319 HydrophobicContact CG2-CZ3 3.89Å; F264-W319 HydrophobicContact CD2-CB 4Å; F264-W319 HydrophobicContact CE2-CB 4.29Å; F315-W319 AromaticContact CD2-CD1 3.27Å; F315-W319 HydrophobicContact CD2-CG 4.07Å; F315-W319 AromaticContact CD2-NE1 3.53Å; F315-W319 HydrophobicContact CE2-CB 4.41Å; F315-W319 AromaticContact CE2-CD1 3.23Å; F315-W319 AromaticContact CE2-CD2 4Å; F315-W319 HydrophobicContact CE2-CD2 4Å; F315-W319 AromaticContact CE2-CE2 3.94Å; F315-W319 AromaticContact CE2-CG 3.61Å; F315-W319 HydrophobicContact CE2-CG 3.61Å; F315-W319 AromaticContact CE2-NE1 3.39Å; F315-W319 HydrophobicContact CZ-CB 4.25Å; F315-W319 AromaticContact CZ-CD1 3.92Å; F315-W319 HydrophobicContact CZ-CD2 4.38Å; F315-W319 AromaticContact CZ-CG 3.89Å; F315-W319 HydrophobicContact CZ-CG 3.89Å; F315-W319 WeakPolarHBondContact O-CB 3.47Å; F315-W319 PolarHBondContact O-N 3.29Å; A316-W319 PolarHBondContact O-N 3.46Å; W319-L322 HydrophobicContact CE3-CD2 4.28Å; W319-L322 HydrophobicContact CZ3-CD2 4Å; W319-L322 PolarHBondContact O-N 3.23Å; W319-H323 AromaticContact CE3-NE2 3.76Å; W319-H323 PolarHBondContact O-CD2 3.44Å; W319-H323 VanDerWaalsContact O-CD2 3.27Å; W319-H323 PolarHBondContact O-N 3.46Å; W319-A358 HydrophobicContact CD2-CB 4.14Å; W319-A358 HydrophobicContact CE3-CB 4.18Å; W319-A358 HydrophobicContact CH2-CB 3.95Å; W319-A358 HydrophobicContact CZ2-CB 4.01Å; W319-A358 HydrophobicContact CZ3-CB 4.1Å; W319-N361 PolarHBondContact NE1-ND2 3.43Å
320	F	90.5	Very high	87.2	Confident	99 Å²	99	34.5 Å²	34.5	43%	0.434	18%	0.176	S	C	.	.	H	α-helix	trans	-57.1	-47.3	-176	176.1	-104.1	0	0	0	113.8	F264 A316 L322 H323 L324	F264-F320 HydrophobicContact CE1-CD2 4.24Å; F264-F320 HydrophobicContact CE2-CB 3.91Å; F264-F320 HydrophobicContact CZ-CB 3.87Å; F264-F320 AromaticContact CZ-CD2 3.77Å; F264-F320 HydrophobicContact CZ-CD2 3.77Å; F264-F320 HydrophobicContact CZ-CG 4.32Å; A316-F320 WeakPolarHBondContact O-CB 3.28Å; A316-F320 PolarHBondContact O-N 3.22Å; F320-L322 VanDerWaalsContact C-N 3.28Å; F320-L322 PolarHBondContact O-N 3.39Å; F320-H323 PolarHBondContact O-N 2.7Å; F320-L324 HydrophobicContact CE1-CD2 3.81Å; F320-L324 HydrophobicContact CZ-CB 4.42Å; F320-L324 HydrophobicContact CZ-CD1 4.49Å; F320-L324 HydrophobicContact CZ-CD2 3.92Å; F320-L324 VanDerWaalsContact O-CB 3.29Å; F320-L324 WeakPolarHBondContact O-CB 3.3Å; F320-L324 PolarHBondContact O-N 3.09Å
321	P	89.3	Confident	87.3	Confident	31 Å²	31	37.2 Å²	37.2	20%	0.201	19%	0.192	C	C	.	.	H	α-helix	trans	-61	-36.7	-178.1	-25.7	37.3	0	0	0	113.2	L317 S325 L357	L317-P321 VanDerWaalsContact O-CD 3.27Å; L317-P321 WeakPolarHBondContact O-CD 3.28Å; P321-S325 WeakPolarHBondContact O-CB 3.15Å; P321-S325 PolarHBondContact O-N 3.41Å; P321-S325 PolarHBondContact O-OG 2.87Å; P321-L357 HydrophobicContact CG-CD2 3.76Å
322	L	88.4	Confident	87.2	Confident	6 Å²	6	40.5 Å²	40.5	3%	0.031	21%	0.212	C	C	.	.	H	α-helix	trans	-67.7	-43.9	177.7	-178.7	61.6	0	0	0	112.4	W319 F320 S325 R326 D351 I355 A358	W319-L322 HydrophobicContact CE3-CD2 4.28Å; W319-L322 HydrophobicContact CZ3-CD2 4Å; W319-L322 PolarHBondContact O-N 3.23Å; F320-L322 VanDerWaalsContact C-N 3.28Å; F320-L322 PolarHBondContact O-N 3.39Å; L322-S325 PolarHBondContact O-OG 2.69Å; L322-R326 VanDerWaalsContact O-CG 3.29Å; L322-R326 WeakPolarHBondContact O-CG 3.33Å; L322-R326 PolarHBondContact O-N 2.88Å; L322-D351 VanDerWaalsContact CD1-OD1 3.29Å; L322-D351 WeakPolarHBondContact CD1-OD1 3.39Å; L322-I355 HydrophobicContact CD1-CG1 3.8Å; L322-A358 HydrophobicContact CD2-CB 3.87Å
323	H	90.3	Very high	86.8	Confident	7 Å²	7	43.4 Å²	43.4	3%	0.032	22%	0.223	C	C	.	.	H	α-helix	trans	-68.8	-39.7	177.2	-76.3	-71.9	0	0	0	111.3	F260 F264 W319 F320 R326 I327	F260-H323 HydrophobicContact CD2-CB 3.86Å; F264-H323 AromaticContact CD2-CD2 3.87Å; W319-H323 AromaticContact CE3-NE2 3.76Å; W319-H323 PolarHBondContact O-CD2 3.44Å; W319-H323 VanDerWaalsContact O-CD2 3.27Å; W319-H323 PolarHBondContact O-N 3.46Å; F320-H323 PolarHBondContact O-N 2.7Å; H323-R326 PolarHBondContact O-N 2.89Å; H323-I327 VanDerWaalsContact O-CG1 3.3Å; H323-I327 WeakPolarHBondContact O-CG1 3.44Å; H323-I327 PolarHBondContact O-N 3.47Å
324	L	89.2	Confident	86.2	Confident	70 Å²	70	45.2 Å²	45.2	37%	0.366	23%	0.231	S	C	.	.	H	α-helix	trans	-62.1	-48.2	177.7	-178.4	63.8	0	0	0	111.5	F320 R326 I327 L328	F320-L324 HydrophobicContact CE1-CD2 3.81Å; F320-L324 HydrophobicContact CZ-CB 4.42Å; F320-L324 HydrophobicContact CZ-CD1 4.49Å; F320-L324 HydrophobicContact CZ-CD2 3.92Å; F320-L324 VanDerWaalsContact O-CB 3.29Å; F320-L324 WeakPolarHBondContact O-CB 3.3Å; F320-L324 PolarHBondContact O-N 3.09Å; L324-R326 VanDerWaalsContact C-N 3.3Å; L324-R326 PolarHBondContact O-N 3.05Å; L324-I327 PolarHBondContact O-N 2.03Å; L324-L328 HydrophobicContact CD1-CD1 3.88Å; L324-L328 HydrophobicContact CD1-CD2 4.5Å; L324-L328 HydrophobicContact CD1-CG 3.92Å; L324-L328 HydrophobicContact CD2-CD1 4.39Å; L324-L328 HydrophobicContact CG-CD1 3.76Å; L324-L328 HydrophobicContact CG-CG 4.21Å; L324-L328 WeakPolarHBondContact O-CB 3.02Å; L324-L328 VanDerWaalsContact O-CG 3.28Å; L324-L328 WeakPolarHBondContact O-CG 3.39Å; L324-L328 PolarHBondContact O-N 2.86Å
325	S	86.1	Confident	85.3	Confident	4 Å²	4	49.3 Å²	49.3	3%	0.028	25%	0.25	C	S	.	.	H	α-helix	trans	-58.7	-41.6	179.6	65.9	0	0	0	0	112	P321 L322 K329	P321-S325 WeakPolarHBondContact O-CB 3.15Å; P321-S325 PolarHBondContact O-N 3.41Å; P321-S325 PolarHBondContact O-OG 2.87Å; L322-S325 PolarHBondContact O-OG 2.69Å; S325-K329 VanDerWaalsContact O-CB 3.23Å; S325-K329 WeakPolarHBondContact O-CB 3.37Å; S325-K329 PolarHBondContact O-N 3.01Å
326	R	86.8	Confident	84.3	Confident	49 Å²	49	57.1 Å²	57.1	19%	0.185	29%	0.289	C	S	.	.	H	α-helix	trans	-68.4	-44	179.2	-69.7	176	-176.7	-151	-1.1	112.8	L322 H323 L324 K329 K330 D351	L322-R326 VanDerWaalsContact O-CG 3.29Å; L322-R326 WeakPolarHBondContact O-CG 3.33Å; L322-R326 PolarHBondContact O-N 2.88Å; H323-R326 PolarHBondContact O-N 2.89Å; L324-R326 VanDerWaalsContact C-N 3.3Å; L324-R326 PolarHBondContact O-N 3.05Å; R326-K329 PolarHBondContact O-N 3.03Å; R326-K330 PolarHBondContact O-N 2.92Å; R326-K330 VanDerWaalsContact O-N 3.1Å; R326-D351 IonicContact NE-OD1 3.94Å
327	I	89.3	Confident	83.6	Confident	24 Å²	24	59.4 Å²	59.4	12%	0.123	30%	0.298	C	S	.	.	H	α-helix	trans	-66.6	-46.1	177.3	-65.3	-62.9	0	0	0	110.4	D256 W257 H323 L324 K329 K330 T331	D256-I327 HydrophobicContact CB-CD1 4.13Å; W257-I327 HydrophobicContact CD2-CD1 3.91Å; W257-I327 HydrophobicContact CE3-CD1 3.89Å; W257-I327 HydrophobicContact CG-CD1 4.45Å; W257-I327 HydrophobicContact CH2-CD1 4.4Å; W257-I327 HydrophobicContact CH2-CG2 4Å; W257-I327 HydrophobicContact CZ2-CD1 4.42Å; W257-I327 HydrophobicContact CZ2-CG2 4.36Å; W257-I327 HydrophobicContact CZ3-CD1 4.14Å; W257-I327 HydrophobicContact CZ3-CG2 4.42Å; H323-I327 VanDerWaalsContact O-CG1 3.3Å; H323-I327 WeakPolarHBondContact O-CG1 3.44Å; H323-I327 PolarHBondContact O-N 3.47Å; L324-I327 PolarHBondContact O-N 2.03Å; I327-K329 VanDerWaalsContact C-N 3.32Å; I327-K329 PolarHBondContact O-N 3.21Å; I327-K330 WeakPolarHBondContact O-CA 3.09Å; I327-K330 WeakPolarHBondContact O-CB 3.29Å; I327-K330 PolarHBondContact O-N 2.9Å; I327-T331 HydrophobicContact CG2-CG2 4.21Å; I327-T331 WeakPolarHBondContact O-CG2 3.43Å; I327-T331 PolarHBondContact O-N 3.44Å; I327-T331 PolarHBondContact O-OG1 2.88Å; I327-T331 VanDerWaalsContact O-OG1 3.07Å
328	L	86.2	Confident	82.6	Confident	61 Å²	61	64.3 Å²	64.3	32%	0.319	32%	0.315	S	S	.	.	H	α-helix	trans	-60.1	-42.2	176.7	-72.7	175.9	0	0	0	111.9	L324 K330 T331 V332 L347	L324-L328 HydrophobicContact CD1-CD1 3.88Å; L324-L328 HydrophobicContact CD1-CD2 4.5Å; L324-L328 HydrophobicContact CD1-CG 3.92Å; L324-L328 HydrophobicContact CD2-CD1 4.39Å; L324-L328 HydrophobicContact CG-CD1 3.76Å; L324-L328 HydrophobicContact CG-CG 4.21Å; L324-L328 WeakPolarHBondContact O-CB 3.02Å; L324-L328 VanDerWaalsContact O-CG 3.28Å; L324-L328 WeakPolarHBondContact O-CG 3.39Å; L324-L328 PolarHBondContact O-N 2.86Å; L328-K330 PolarHBondContact O-N 2.95Å; L328-T331 PolarHBondContact O-N 2.91Å; L328-V332 HydrophobicContact CD2-CG2 3.94Å; L328-V332 VanDerWaalsContact O-CB 3.31Å; L328-V332 WeakPolarHBondContact O-CB 3.32Å; L328-V332 PolarHBondContact O-N 2.84Å; L328-L347 HydrophobicContact CB-CD2 3.86Å
329	K	82.2	Confident	81.8	Confident	67 Å²	67	69 Å²	69	29%	0.291	34%	0.34	S	S	.	.	H	α-helix	trans	-59.9	-32.3	173.9	-174.7	-178.3	177.7	-173.5	0	112.2	S325 R326 I327 Y333 L347	S325-K329 VanDerWaalsContact O-CB 3.23Å; S325-K329 WeakPolarHBondContact O-CB 3.37Å; S325-K329 PolarHBondContact O-N 3.01Å; R326-K329 PolarHBondContact O-N 3.03Å; I327-K329 VanDerWaalsContact C-N 3.32Å; I327-K329 PolarHBondContact O-N 3.21Å; K329-Y333 WeakPolarHBondContact O-CB 3.32Å; K329-L347 HydrophobicContact CB-CD1 4.06Å; K329-L347 HydrophobicContact CG-CD1 4.39Å
330	K	83	Confident	81	Confident	77 Å²	77	71 Å²	71	34%	0.335	35%	0.347	S	S	.	.	H	α-helix	trans	-81.8	-33.2	179.3	-171.8	166.4	-171.5	142.7	0	113.6	D253 R326 I327 L328	D253-K330 VanDerWaalsContact C-NZ 3.26Å; D253-K330 WeakPolarHBondContact O-CE 3.36Å; D253-K330 PolarHBondContact O-NZ 3.37Å; R326-K330 PolarHBondContact O-N 2.92Å; R326-K330 VanDerWaalsContact O-N 3.1Å; I327-K330 WeakPolarHBondContact O-CA 3.09Å; I327-K330 WeakPolarHBondContact O-CB 3.29Å; I327-K330 PolarHBondContact O-N 2.9Å; L328-K330 PolarHBondContact O-N 2.95Å
331	T	84.9	Confident	80	Confident	84 Å²	84	67.2 Å²	67.2	52%	0.515	33%	0.333	S	S	.	.	H	α-helix	trans	-97.3	-30.1	-173	57.1	0	0	0	0	114.1	W257 I327 L328	W257-T331 HydrophobicContact CZ2-CG2 4.04Å; I327-T331 HydrophobicContact CG2-CG2 4.21Å; I327-T331 WeakPolarHBondContact O-CG2 3.43Å; I327-T331 PolarHBondContact O-N 3.44Å; I327-T331 PolarHBondContact O-OG1 2.88Å; I327-T331 VanDerWaalsContact O-OG1 3.07Å; L328-T331 PolarHBondContact O-N 2.91Å
332	V	80.5	Confident	79.3	Confident	75 Å²	75	72.3 Å²	72.3	46%	0.455	35%	0.354	S	S	.	.	T	Hydrogen-bonded Turn	trans	-105.4	-25	-171.9	-171.2	0	0	0	0	112.2	L328 D334 L343	L328-V332 HydrophobicContact CD2-CG2 3.94Å; L328-V332 VanDerWaalsContact O-CB 3.31Å; L328-V332 WeakPolarHBondContact O-CB 3.32Å; L328-V332 PolarHBondContact O-N 2.84Å; V332-D334 PolarHBondContact O-N 3.42Å; V332-L343 HydrophobicContact CG1-CD2 3.89Å
333	Y	76.4	Confident	78.8	Confident	67 Å²	67	74.3 Å²	74.3	26%	0.263	36%	0.364	S	S	.	.			trans	-72.3	112.8	179.1	-179	-99.1	0	0	0	110.6	K329 E335 R340 L344	K329-Y333 WeakPolarHBondContact O-CB 3.32Å; Y333-E335 HydrophobicContact CE1-CG 3.76Å; Y333-R340 HydrophobicContact CE2-CB 4.21Å; Y333-L344 HydrophobicContact CD2-CD1 4.41Å; Y333-L344 HydrophobicContact CE2-CB 4.22Å; Y333-L344 HydrophobicContact CE2-CD1 4.22Å; Y333-L344 HydrophobicContact CE2-CD2 4.26Å; Y333-L344 HydrophobicContact CE2-CG 4.48Å
334	D	74.1	Confident	78	Confident	91 Å²	91	74.9 Å²	74.9	49%	0.487	37%	0.368	S	S	.	.			trans	-109.1	128.2	169.9	-171.9	-10.7	0	0	0	109.3	V332 M336 D337	V332-D334 PolarHBondContact O-N 3.42Å; D334-M336 PolarHBondContact O-N 3.48Å; D334-M336 WeakPolarHBondContact OD1-CB 3.33Å; D334-M336 PolarHBondContact OD1-N 3.13Å; D334-D337 HydrophobicContact CB-CB 4.37Å; D334-D337 PolarHBondContact O-N 3.17Å
335	E	68.3	Low	77.4	Confident	88 Å²	88	73.4 Å²	73.4	41%	0.411	36%	0.363	S	S	.	.	T	Hydrogen-bonded Turn	trans	-64.1	-22.1	177.2	-67.9	-171.8	172.3	0	0	112.3	H52 Y333 R340	H52-E335 IonicContact CE1-OE1 3.49Å; H52-E335 PolarHBondContact CE1-OE1 3.04Å; H52-E335 IonicContact CG-OE1 2.73Å; H52-E335 IonicContact ND1-OE1 3.18Å; H52-E335 PolarHBondContact ND1-OE1 3.16Å; Y333-E335 HydrophobicContact CE1-CG 3.76Å; E335-R340 VanDerWaalsContact O-CD 3.26Å; E335-R340 WeakPolarHBondContact O-CD 3.44Å
336	M	66	Low	77.1	Confident	164 Å²	164	77.9 Å²	77.9	81%	0.808	38%	0.382	S	S	*	.	T	Hydrogen-bonded Turn	trans	-90.2	-6.9	-176.3	-58.9	-58	-66.6	0	0	114.2	D334	D334-M336 PolarHBondContact O-N 3.48Å; D334-M336 WeakPolarHBondContact OD1-CB 3.33Å; D334-M336 PolarHBondContact OD1-N 3.13Å
337	D	75	Confident	76.7	Confident	70 Å²	70	75.9 Å²	75.9	37%	0.374	38%	0.375	S	S	.	.			trans	-77.9	139.5	-179.5	-170.6	1	0	0	0	112	D334 N339 R340	D334-D337 HydrophobicContact CB-CB 4.37Å; D334-D337 PolarHBondContact O-N 3.17Å; D337-N339 VanDerWaalsContact C-N 3.33Å; D337-N339 PolarHBondContact OD1-N 3.15Å; D337-N339 VanDerWaalsContact OD1-N 3.12Å; D337-R340 HydrophobicContact CB-CB 4.36Å; D337-R340 WeakPolarHBondContact O-CB 3.23Å; D337-R340 WeakPolarHBondContact O-CD 3.48Å; D337-R340 WeakPolarHBondContact O-CG 3.46Å; D337-R340 PolarHBondContact O-N 3.19Å
338	K	69.1	Low	76	Confident	198 Å²	198	76.2 Å²	76.2	86%	0.861	38%	0.377	S	S	*	.	T	Hydrogen-bonded Turn	trans	-70.4	-29.3	176.6	-65.6	-177.4	-175.5	177.5	0	112.1
339	N	72.4	Confident	75.5	Confident	107 Å²	107	75.9 Å²	75.9	57%	0.572	38%	0.375	S	S	*	.	T	Hydrogen-bonded Turn	trans	-92.6	8	179.5	-66.7	-17.3	0	0	0	113.5	D337 C341 E342 L343	D337-N339 VanDerWaalsContact C-N 3.33Å; D337-N339 PolarHBondContact OD1-N 3.15Å; D337-N339 VanDerWaalsContact OD1-N 3.12Å; N339-C341 PolarHBondContact O-N 3.03Å; N339-E342 PolarHBondContact O-N 3.25Å; N339-E342 VanDerWaalsContact O-N 3.14Å; N339-L343 PolarHBondContact O-N 2.83Å
340	R	72.5	Confident	75.4	Confident	52 Å²	52	75.6 Å²	75.6	20%	0.196	38%	0.376	C	S	.	.	H	α-helix	trans	-54.4	-31.1	-176.2	68.2	-172.7	174	117	7.5	114.2	S67 Y333 E335 D337 L344	S67-R340 PolarHBondContact O-NH2 3.48Å; Y333-R340 HydrophobicContact CE2-CB 4.21Å; E335-R340 VanDerWaalsContact O-CD 3.26Å; E335-R340 WeakPolarHBondContact O-CD 3.44Å; D337-R340 HydrophobicContact CB-CB 4.36Å; D337-R340 WeakPolarHBondContact O-CB 3.23Å; D337-R340 WeakPolarHBondContact O-CD 3.48Å; D337-R340 WeakPolarHBondContact O-CG 3.46Å; D337-R340 PolarHBondContact O-N 3.19Å; R340-L344 WeakPolarHBondContact O-CB 3.22Å; R340-L344 PolarHBondContact O-N 3.28Å
341	C	70.2	Confident	75.3	Confident	19 Å²	19	73.5 Å²	73.5	13%	0.128	37%	0.368	C	S	.	.	H	α-helix	trans	-74.4	-35.3	-177.5	-62.2	0	0	0	0	113	C69 N339 S345	C69-C341 WeakPolarHBondContact CA-SG 3.2Å; C69-C341 HydrophobicContact CB-CB 3.83Å; C69-C341 WeakPolarHBondContact CB-SG 3.17Å; C69-C341 WeakPolarHBondContact SG-CA 3.28Å; C69-C341 WeakPolarHBondContact SG-CB 3.38Å; C69-C341 CovalentContact SG-SG 2.04Å; C69-C341 PolarHBondContact SG-SG 3.49Å; N339-C341 PolarHBondContact O-N 3.03Å; C341-S345 WeakPolarHBondContact O-CB 3.24Å; C341-S345 PolarHBondContact O-N 3.29Å; C341-S345 PolarHBondContact O-OG 2.87Å
342	E	75.2	Confident	74.9	Confident	139 Å²	139	71 Å²	71	65%	0.65	35%	0.349	S	S	*	.	H	α-helix	trans	-70.8	-46.6	175.6	-172.9	177.3	178.7	0	0	110.3	N339 L344 S345 F346	N339-E342 PolarHBondContact O-N 3.25Å; N339-E342 VanDerWaalsContact O-N 3.14Å; E342-L344 PolarHBondContact O-N 3.47Å; E342-S345 WeakPolarHBondContact O-CB 3.44Å; E342-S345 PolarHBondContact O-N 2.87Å; E342-F346 PolarHBondContact O-N 3.41Å
343	L	76.9	Confident	74.9	Confident	48 Å²	48	68.6 Å²	68.6	25%	0.251	33%	0.334	S	S	.	.	H	α-helix	trans	-58.5	-46	174.4	178.5	63.5	0	0	0	111.6	V332 N339 S345 F346 L347	V332-L343 HydrophobicContact CG1-CD2 3.89Å; N339-L343 PolarHBondContact O-N 2.83Å; L343-S345 VanDerWaalsContact C-N 3.33Å; L343-S345 PolarHBondContact O-N 3.02Å; L343-F346 PolarHBondContact O-N 2.94Å; L343-L347 HydrophobicContact CD1-CD1 4.05Å; L343-L347 HydrophobicContact CD1-CG 4.15Å; L343-L347 HydrophobicContact CG-CD1 3.87Å; L343-L347 HydrophobicContact CG-CG 4.38Å; L343-L347 WeakPolarHBondContact O-CB 3.43Å; L343-L347 VanDerWaalsContact O-CG 3.23Å; L343-L347 WeakPolarHBondContact O-CG 3.49Å; L343-L347 PolarHBondContact O-N 2.87Å
344	L	74.8	Confident	75.4	Confident	19 Å²	19	65.4 Å²	65.4	10%	0.099	32%	0.321	C	S	.	.	H	α-helix	trans	-63.2	-39.7	178.1	-175.9	63.3	0	0	0	111.8	Y333 R340 E342 L347 L348	Y333-L344 HydrophobicContact CD2-CD1 4.41Å; Y333-L344 HydrophobicContact CE2-CB 4.22Å; Y333-L344 HydrophobicContact CE2-CD1 4.22Å; Y333-L344 HydrophobicContact CE2-CD2 4.26Å; Y333-L344 HydrophobicContact CE2-CG 4.48Å; R340-L344 WeakPolarHBondContact O-CB 3.22Å; R340-L344 PolarHBondContact O-N 3.28Å; E342-L344 PolarHBondContact O-N 3.47Å; L344-L347 PolarHBondContact O-N 3.47Å; L344-L348 HydrophobicContact CD1-CG 4.47Å; L344-L348 HydrophobicContact CG-CD1 4.16Å; L344-L348 HydrophobicContact CG-CG 4.49Å; L344-L348 WeakPolarHBondContact O-CB 3.29Å; L344-L348 WeakPolarHBondContact O-CG 3.29Å; L344-L348 PolarHBondContact O-N 2.96Å
345	S	75.3	Confident	75.8	Confident	39 Å²	39	62.9 Å²	62.9	27%	0.273	31%	0.307	S	S	.	.	H	α-helix	trans	-61.7	-46	176.2	-60	0	0	0	0	111.7	T73 C341 E342 L343 L348 L349	T73-S345 WeakPolarHBondContact CG2-OG 3.42Å; C341-S345 WeakPolarHBondContact O-CB 3.24Å; C341-S345 PolarHBondContact O-N 3.29Å; C341-S345 PolarHBondContact O-OG 2.87Å; E342-S345 WeakPolarHBondContact O-CB 3.44Å; E342-S345 PolarHBondContact O-N 2.87Å; L343-S345 VanDerWaalsContact C-N 3.33Å; L343-S345 PolarHBondContact O-N 3.02Å; S345-L348 PolarHBondContact O-N 3.26Å; S345-L349 PolarHBondContact O-N 3.49Å; S345-L349 VanDerWaalsContact O-N 3.11Å
346	F	79.4	Confident	76.6	Confident	97 Å²	97	59.6 Å²	59.6	43%	0.425	29%	0.293	S	S	.	.	H	α-helix	trans	-62.4	-46.1	175.5	173.9	-99.7	0	0	0	112.2	E342 L343 L348 L349 M350	E342-F346 PolarHBondContact O-N 3.41Å; L343-F346 PolarHBondContact O-N 2.94Å; F346-L348 VanDerWaalsContact C-N 3.33Å; F346-L348 PolarHBondContact O-N 3.33Å; F346-L349 WeakPolarHBondContact O-CB 3.29Å; F346-L349 PolarHBondContact O-N 3.37Å; F346-M350 HydrophobicContact CD1-CG 4.43Å; F346-M350 HydrophobicContact CE1-CE 4.25Å; F346-M350 HydrophobicContact CE1-CG 3.99Å; F346-M350 HydrophobicContact CE2-CE 3.74Å; F346-M350 HydrophobicContact CE2-CG 4.3Å; F346-M350 HydrophobicContact CZ-CE 3.37Å; F346-M350 HydrophobicContact CZ-CG 3.93Å; F346-M350 PolarHBondContact O-N 2.96Å
347	L	79.4	Confident	77.6	Confident	8 Å²	8	53.2 Å²	53.2	4%	0.042	26%	0.262	C	S	.	.	H	α-helix	trans	-64.5	-36.5	178.8	-71.4	172.1	0	0	0	112.4	L328 K329 L343 L344 M350 D351	L328-L347 HydrophobicContact CB-CD2 3.86Å; K329-L347 HydrophobicContact CB-CD1 4.06Å; K329-L347 HydrophobicContact CG-CD1 4.39Å; L343-L347 HydrophobicContact CD1-CD1 4.05Å; L343-L347 HydrophobicContact CD1-CG 4.15Å; L343-L347 HydrophobicContact CG-CD1 3.87Å; L343-L347 HydrophobicContact CG-CG 4.38Å; L343-L347 WeakPolarHBondContact O-CB 3.43Å; L343-L347 VanDerWaalsContact O-CG 3.23Å; L343-L347 WeakPolarHBondContact O-CG 3.49Å; L343-L347 PolarHBondContact O-N 2.87Å; L344-L347 PolarHBondContact O-N 3.47Å; L347-M350 PolarHBondContact O-N 2.86Å; L347-D351 WeakPolarHBondContact O-CB 3.5Å; L347-D351 PolarHBondContact O-N 3.4Å
348	L	73.2	Confident	78.2	Confident	30 Å²	30	50 Å²	50	16%	0.157	25%	0.245	C	C	.	.	H	α-helix	trans	-63.4	-44.8	173.9	-76.2	168.6	0	0	0	111.2	L48 T73 L344 S345 F346 M350 D351 Y352	L48-L348 HydrophobicContact CD2-CD2 4.09Å; T73-L348 HydrophobicContact CG2-CD1 4.37Å; L344-L348 HydrophobicContact CD1-CG 4.47Å; L344-L348 HydrophobicContact CG-CD1 4.16Å; L344-L348 HydrophobicContact CG-CG 4.49Å; L344-L348 WeakPolarHBondContact O-CB 3.29Å; L344-L348 WeakPolarHBondContact O-CG 3.29Å; L344-L348 PolarHBondContact O-N 2.96Å; S345-L348 PolarHBondContact O-N 3.26Å; F346-L348 VanDerWaalsContact C-N 3.33Å; F346-L348 PolarHBondContact O-N 3.33Å; L348-M350 VanDerWaalsContact C-N 3.34Å; L348-M350 PolarHBondContact O-N 3.23Å; L348-D351 PolarHBondContact O-N 3.33Å; L348-Y352 WeakPolarHBondContact O-CD2 3.32Å; L348-Y352 PolarHBondContact O-N 3.27Å
349	L	77.2	Confident	78.9	Confident	54 Å²	54	40.6 Å²	40.6	28%	0.283	20%	0.204	S	C	.	.	H	α-helix	trans	-60.5	-45.3	175.5	-179	63.7	0	0	0	111.4	F19 F79 S345 F346 D351 Y352 I353	F19-L349 HydrophobicContact CE1-CD2 3.68Å; F19-L349 HydrophobicContact CZ-CD2 3.92Å; F79-L349 HydrophobicContact CD2-CD1 3.81Å; F79-L349 HydrophobicContact CE2-CD1 3.3Å; F79-L349 HydrophobicContact CZ-CD1 3.87Å; S345-L349 PolarHBondContact O-N 3.49Å; S345-L349 VanDerWaalsContact O-N 3.11Å; F346-L349 WeakPolarHBondContact O-CB 3.29Å; F346-L349 PolarHBondContact O-N 3.37Å; L349-D351 VanDerWaalsContact C-N 3.34Å; L349-D351 PolarHBondContact O-N 3Å; L349-Y352 PolarHBondContact O-N 2.83Å; L349-I353 HydrophobicContact CD1-CD1 4.34Å; L349-I353 HydrophobicContact CG-CD1 4.06Å; L349-I353 WeakPolarHBondContact O-CG1 3.33Å; L349-I353 PolarHBondContact O-N 3.06Å
350	M	79.4	Confident	79.7	Confident	61 Å²	61	36.6 Å²	36.6	30%	0.3	18%	0.182	S	C	.	.	H	α-helix	trans	-62.1	-38.4	175.6	-76.8	-65.3	-168.7	0	0	112.7	F346 L347 L348 I353 G354	F346-M350 HydrophobicContact CD1-CG 4.43Å; F346-M350 HydrophobicContact CE1-CE 4.25Å; F346-M350 HydrophobicContact CE1-CG 3.99Å; F346-M350 HydrophobicContact CE2-CE 3.74Å; F346-M350 HydrophobicContact CE2-CG 4.3Å; F346-M350 HydrophobicContact CZ-CE 3.37Å; F346-M350 HydrophobicContact CZ-CG 3.93Å; F346-M350 PolarHBondContact O-N 2.96Å; L347-M350 PolarHBondContact O-N 2.86Å; L348-M350 VanDerWaalsContact C-N 3.34Å; L348-M350 PolarHBondContact O-N 3.23Å; M350-I353 PolarHBondContact O-N 3.5Å; M350-G354 PolarHBondContact O-N 2.8Å
351	D	80.1	Confident	80.4	Confident	34 Å²	34	34.1 Å²	34.1	18%	0.182	17%	0.173	C	C	.	.	H	α-helix	trans	-63.7	-43.6	175.1	-168	51	0	0	0	111.2	L322 R326 L347 L348 L349 G354 I355	L322-D351 VanDerWaalsContact CD1-OD1 3.29Å; L322-D351 WeakPolarHBondContact CD1-OD1 3.39Å; R326-D351 IonicContact NE-OD1 3.94Å; L347-D351 WeakPolarHBondContact O-CB 3.5Å; L347-D351 PolarHBondContact O-N 3.4Å; L348-D351 PolarHBondContact O-N 3.33Å; L349-D351 VanDerWaalsContact C-N 3.34Å; L349-D351 PolarHBondContact O-N 3Å; D351-G354 PolarHBondContact O-N 3.34Å; D351-I355 VanDerWaalsContact O-CG1 3.24Å; D351-I355 WeakPolarHBondContact O-CG1 3.27Å; D351-I355 PolarHBondContact O-N 2.83Å
352	Y	76.7	Confident	81.2	Confident	30 Å²	30	33.5 Å²	33.5	12%	0.118	17%	0.169	C	C	.	.	H	α-helix	trans	-63	-44.8	174.3	-82.6	-75.3	0	0	0	113	L48 I75 F79 L141 L348 L349 G354 I355 N356	L48-Y352 WeakPolarHBondContact CD1-OH 3.04Å; L48-Y352 HydrophobicContact CD2-CE2 3.74Å; I75-Y352 HydrophobicContact CD1-CE2 3.75Å; F79-Y352 HydrophobicContact CE1-CD1 4.29Å; F79-Y352 HydrophobicContact CE1-CD2 4.34Å; F79-Y352 HydrophobicContact CE1-CG 4.01Å; F79-Y352 HydrophobicContact CZ-CG 4.07Å; L141-Y352 HydrophobicContact CD1-CE1 3.83Å; L348-Y352 WeakPolarHBondContact O-CD2 3.32Å; L348-Y352 PolarHBondContact O-N 3.27Å; L349-Y352 PolarHBondContact O-N 2.83Å; Y352-G354 VanDerWaalsContact C-N 3.3Å; Y352-G354 PolarHBondContact O-N 3Å; Y352-I355 PolarHBondContact O-N 2.92Å; Y352-N356 PolarHBondContact O-N 3.4Å; Y352-N356 PolarHBondContact O-ND2 2.75Å
353	I	80.8	Confident	81.7	Confident	26 Å²	26	27.2 Å²	27.2	13%	0.133	14%	0.14	C	C	.	.	H	α-helix	trans	-61.4	-44.1	176.4	-68.4	168.4	0	0	0	109.7	V15 F19 L349 M350 I355 N356 L357	V15-I353 HydrophobicContact CG1-CD1 4.23Å; V15-I353 HydrophobicContact CG1-CG2 4.08Å; F19-I353 HydrophobicContact CE2-CD1 3.88Å; F19-I353 HydrophobicContact CZ-CD1 3.65Å; L349-I353 HydrophobicContact CD1-CD1 4.34Å; L349-I353 HydrophobicContact CG-CD1 4.06Å; L349-I353 WeakPolarHBondContact O-CG1 3.33Å; L349-I353 PolarHBondContact O-N 3.06Å; M350-I353 PolarHBondContact O-N 3.5Å; I353-I355 PolarHBondContact O-N 3.46Å; I353-N356 PolarHBondContact O-N 3.11Å; I353-L357 WeakPolarHBondContact O-CB 3.36Å; I353-L357 PolarHBondContact O-N 3.13Å
354	G	86.9	Confident	82.2	Confident	0 Å²	0	26.2 Å²	26.2	0%	0	14%	0.135	C	C	.	.	H	α-helix	trans	-60.2	-42	176.4	0	0	0	0	0	112.9	M350 D351 Y352 L357 A358	M350-G354 PolarHBondContact O-N 2.8Å; D351-G354 PolarHBondContact O-N 3.34Å; Y352-G354 VanDerWaalsContact C-N 3.3Å; Y352-G354 PolarHBondContact O-N 3Å; G354-L357 PolarHBondContact O-N 3.11Å; G354-A358 VanDerWaalsContact O-CB 3.25Å; G354-A358 WeakPolarHBondContact O-CB 3.19Å; G354-A358 PolarHBondContact O-N 3.44Å
355	I	83.9	Confident	82.7	Confident	37 Å²	37	25.5 Å²	25.5	19%	0.19	13%	0.131	C	C	.	.	H	α-helix	trans	-61.8	-47.7	174.9	-70.8	164.6	0	0	0	110.3	L322 D351 Y352 I353 L357 A358 T359	L322-I355 HydrophobicContact CD1-CG1 3.8Å; D351-I355 VanDerWaalsContact O-CG1 3.24Å; D351-I355 WeakPolarHBondContact O-CG1 3.27Å; D351-I355 PolarHBondContact O-N 2.83Å; Y352-I355 PolarHBondContact O-N 2.92Å; I353-I355 PolarHBondContact O-N 3.46Å; I355-L357 VanDerWaalsContact C-N 3.33Å; I355-L357 PolarHBondContact O-N 2.84Å; I355-A358 PolarHBondContact O-N 3.36Å; I355-T359 HydrophobicContact CG2-CG2 4.27Å; I355-T359 WeakPolarHBondContact O-CG2 3.32Å; I355-T359 PolarHBondContact O-N 2.83Å; I355-T359 PolarHBondContact O-OG1 3.47Å
356	N	83.7	Confident	83.3	Confident	20 Å²	20	23.9 Å²	23.9	11%	0.107	12%	0.119	C	C	.	.	H	α-helix	trans	-59.8	-44.9	177.6	-78.3	-73.4	0	0	0	111.6	T83 Y352 I353 T359 M360	T83-N356 WeakPolarHBondContact CG2-ND2 3.16Å; T83-N356 WeakPolarHBondContact CG2-OD1 3.06Å; Y352-N356 PolarHBondContact O-N 3.4Å; Y352-N356 PolarHBondContact O-ND2 2.75Å; I353-N356 PolarHBondContact O-N 3.11Å; N356-T359 PolarHBondContact O-N 3.31Å; N356-T359 PolarHBondContact O-OG1 2.9Å; N356-M360 PolarHBondContact O-N 3.4Å
357	L	87.6	Confident	83.7	Confident	29 Å²	29	22 Å²	22	15%	0.152	11%	0.113	C	C	.	.	H	α-helix	trans	-67.1	-39.8	-180	-144.3	71.6	0	0	0	111.8	L317 C318 P321 I353 G354 I355 T359 M360 N361	L317-L357 VanDerWaalsContact O-CD2 3.28Å; L317-L357 WeakPolarHBondContact O-CD2 3.41Å; C318-L357 WeakPolarHBondContact CB-O 3.41Å; C318-L357 CarbonylContact O-C 3.59Å; P321-L357 HydrophobicContact CG-CD2 3.76Å; I353-L357 WeakPolarHBondContact O-CB 3.36Å; I353-L357 PolarHBondContact O-N 3.13Å; G354-L357 PolarHBondContact O-N 3.11Å; I355-L357 VanDerWaalsContact C-N 3.33Å; I355-L357 PolarHBondContact O-N 2.84Å; L357-T359 PolarHBondContact O-N 3.43Å; L357-M360 HydrophobicContact CD1-CE 4.34Å; L357-M360 VanDerWaalsContact O-CB 3.3Å; L357-M360 WeakPolarHBondContact O-CB 3.49Å; L357-M360 PolarHBondContact O-N 2.89Å; L357-N361 PolarHBondContact O-N 3.22Å
358	A	87.6	Confident	84	Confident	2 Å²	2	21.9 Å²	21.9	2%	0.017	11%	0.113	C	C	.	.	H	α-helix	trans	-62.2	-42.1	173.3	0	0	0	0	0	111.8	C318 W319 L322 G354 I355 M360 N361	C318-A358 PolarHBondContact O-N 3.24Å; W319-A358 HydrophobicContact CD2-CB 4.14Å; W319-A358 HydrophobicContact CE3-CB 4.18Å; W319-A358 HydrophobicContact CH2-CB 3.95Å; W319-A358 HydrophobicContact CZ2-CB 4.01Å; W319-A358 HydrophobicContact CZ3-CB 4.1Å; L322-A358 HydrophobicContact CD2-CB 3.87Å; G354-A358 VanDerWaalsContact O-CB 3.25Å; G354-A358 WeakPolarHBondContact O-CB 3.19Å; G354-A358 PolarHBondContact O-N 3.44Å; I355-A358 PolarHBondContact O-N 3.36Å; A358-M360 VanDerWaalsContact C-N 3.27Å; A358-M360 PolarHBondContact O-N 3.02Å; A358-N361 WeakPolarHBondContact O-CB 3.33Å; A358-N361 PolarHBondContact O-N 2.86Å
359	T	84.7	Confident	84.5	Confident	2 Å²	2	20.7 Å²	20.7	1%	0.012	11%	0.107	C	C	.	.	H	α-helix	trans	-65	-31.7	175.8	67.1	0	0	0	0	112.4	Y129 L134 I355 N356 L357 N361 S362	Y129-T359 HydrophobicContact CE1-CG2 3.71Å; Y129-T359 WeakPolarHBondContact OH-CG2 3.04Å; L134-T359 HydrophobicContact CD1-CG2 4.22Å; I355-T359 HydrophobicContact CG2-CG2 4.27Å; I355-T359 WeakPolarHBondContact O-CG2 3.32Å; I355-T359 PolarHBondContact O-N 2.83Å; I355-T359 PolarHBondContact O-OG1 3.47Å; N356-T359 PolarHBondContact O-N 3.31Å; N356-T359 PolarHBondContact O-OG1 2.9Å; L357-T359 PolarHBondContact O-N 3.43Å; T359-N361 PolarHBondContact O-N 3.34Å; T359-S362 PolarHBondContact O-N 2.96Å
360	M	87.4	Confident	84.9	Confident	22 Å²	22	21 Å²	21	11%	0.108	11%	0.105	C	C	.	.	H	α-helix	trans	-65.6	-28.6	177.8	-162.3	-177.6	-67.5	0	0	112.3	I90 N356 L357 A358 S362 C363 I364	I90-M360 HydrophobicContact CD1-CB 4.01Å; I90-M360 HydrophobicContact CD1-CE 4.3Å; I90-M360 HydrophobicContact CD1-CG 4.29Å; I90-M360 HydrophobicContact CG1-CG 4.42Å; N356-M360 PolarHBondContact O-N 3.4Å; L357-M360 HydrophobicContact CD1-CE 4.34Å; L357-M360 VanDerWaalsContact O-CB 3.3Å; L357-M360 WeakPolarHBondContact O-CB 3.49Å; L357-M360 PolarHBondContact O-N 2.89Å; A358-M360 VanDerWaalsContact C-N 3.27Å; A358-M360 PolarHBondContact O-N 3.02Å; M360-S362 PolarHBondContact O-N 3.01Å; M360-S362 VanDerWaalsContact O-N 3.12Å; M360-C363 PolarHBondContact O-N 3.02Å; M360-C363 PolarHBondContact O-SG 3.03Å; M360-I364 HydrophobicContact CB-CD1 4.3Å; M360-I364 HydrophobicContact CG-CD1 3.67Å; M360-I364 HydrophobicContact CG-CG1 3.98Å; M360-I364 WeakPolarHBondContact O-CG1 3.19Å; M360-I364 PolarHBondContact O-N 3.19Å; M360-I364 HydrophobicContact SD-CD1 3.95Å
361	N	87.5	Confident	85	Confident	1 Å²	1	24.3 Å²	24.3	1%	0.005	12%	0.118	C	C	.	.	H	α-helix	trans	-53	-36.1	176.5	-174.1	64.9	0	0	0	112.2	F315 C318 W319 L357 A358 T359 C363 N365	F315-N361 WeakPolarHBondContact CA-OD1 3.37Å; C318-N361 HydrophobicContact CB-CB 3.92Å; W319-N361 PolarHBondContact NE1-ND2 3.43Å; L357-N361 PolarHBondContact O-N 3.22Å; A358-N361 WeakPolarHBondContact O-CB 3.33Å; A358-N361 PolarHBondContact O-N 2.86Å; T359-N361 PolarHBondContact O-N 3.34Å; N361-C363 VanDerWaalsContact C-N 3.34Å; N361-C363 PolarHBondContact O-N 3.2Å; N361-N365 PolarHBondContact O-ND2 2.74Å
362	S	86.7	Confident	84.7	Confident	5 Å²	5	24.3 Å²	24.3	4%	0.035	12%	0.119	C	C	.	.	H	α-helix	trans	-71.2	-22.5	179.7	-67.8	0	0	0	0	114.3	N98 D126 T359 M360	N98-S362 PolarHBondContact ND2-O 2.91Å; D126-S362 WeakPolarHBondContact OD1-CA 3.41Å; D126-S362 WeakPolarHBondContact OD1-CB 3.47Å; D126-S362 PolarHBondContact OD1-OG 3.33Å; T359-S362 PolarHBondContact O-N 2.96Å; M360-S362 PolarHBondContact O-N 3.01Å; M360-S362 VanDerWaalsContact O-N 3.12Å
363	C	87	Confident	84.8	Confident	8 Å²	8	24 Å²	24	5%	0.054	12%	0.121	C	C	.	.	H	α-helix	trans	-98.4	-21.7	175.8	72	0	0	0	0	113.2	I90 V93 M360 N361 N365 I367	I90-C363 HydrophobicContact CG2-CB 4.31Å; V93-C363 HydrophobicContact CB-CB 4.41Å; V93-C363 HydrophobicContact CG1-CB 4.15Å; M360-C363 PolarHBondContact O-N 3.02Å; M360-C363 PolarHBondContact O-SG 3.03Å; N361-C363 VanDerWaalsContact C-N 3.34Å; N361-C363 PolarHBondContact O-N 3.2Å; C363-N365 VanDerWaalsContact C-N 3.34Å; C363-I367 WeakPolarHBondContact O-CD1 3.38Å; C363-I367 WeakPolarHBondContact O-CG1 3.42Å
364	I	87.4	Confident	84.7	Confident	27 Å²	27	31.2 Å²	31.2	14%	0.138	15%	0.152	C	C	.	.	H	α-helix	trans	-70.8	-30	177.5	-66.1	165.2	0	0	0	111.5	I314 M360 I367 A368	I314-I364 HydrophobicContact CB-CG2 4.45Å; I314-I364 HydrophobicContact CD1-CG2 3.8Å; I314-I364 HydrophobicContact CG1-CG2 4.1Å; I314-I364 HydrophobicContact CG2-CB 4.04Å; I314-I364 HydrophobicContact CG2-CD1 4.15Å; I314-I364 HydrophobicContact CG2-CG2 3.51Å; M360-I364 HydrophobicContact CB-CD1 4.3Å; M360-I364 HydrophobicContact CG-CD1 3.67Å; M360-I364 HydrophobicContact CG-CG1 3.98Å; M360-I364 WeakPolarHBondContact O-CG1 3.19Å; M360-I364 PolarHBondContact O-N 3.19Å; M360-I364 HydrophobicContact SD-CD1 3.95Å; I364-I367 CarbonylContact O-C 3.58Å; I364-I367 WeakPolarHBondContact O-CA 3.4Å; I364-I367 WeakPolarHBondContact O-CB 3.47Å; I364-I367 PolarHBondContact O-N 3.24Å; I364-A368 HydrophobicContact CG2-CB 4.45Å; I364-A368 WeakPolarHBondContact O-CB 3.23Å; I364-A368 PolarHBondContact O-N 3.1Å
365	N	85.2	Confident	84.4	Confident	4 Å²	4	36.1 Å²	36.1	2%	0.021	17%	0.173	C	C	.	.	H	α-helix	trans	-54	-53.2	-176.1	-71.6	-24.4	0	0	0	113.8	D126 N361 C363 I367 A368 L369	D126-N365 PolarHBondContact OD2-ND2 2.78Å; N361-N365 PolarHBondContact O-ND2 2.74Å; C363-N365 VanDerWaalsContact C-N 3.34Å; N365-I367 VanDerWaalsContact C-N 3.32Å; N365-I367 PolarHBondContact O-N 2.58Å; N365-A368 PolarHBondContact O-N 2.86Å; N365-L369 WeakPolarHBondContact O-CG 3.28Å; N365-L369 PolarHBondContact O-N 3.24Å
366	P	87.3	Confident	84.4	Confident	4 Å²	4	34.8 Å²	34.8	3%	0.026	17%	0.166	C	C	.	.	H	α-helix	trans	-58.9	-39.1	172.7	-26	33.6	0	0	0	114.1	N98 L101 L369 Y370 F380	N98-P366 HydrophobicContact CB-CG 4.43Å; N98-P366 WeakPolarHBondContact OD1-CD 3.3Å; N98-P366 WeakPolarHBondContact OD1-CG 3.34Å; L101-P366 HydrophobicContact CD2-CG 4.34Å; P366-L369 PolarHBondContact O-N 3.14Å; P366-Y370 WeakPolarHBondContact O-CB 3.45Å; P366-Y370 PolarHBondContact O-N 3.24Å; P366-F380 HydrophobicContact CB-CZ 4.13Å
367	I	87.9	Confident	84.5	Confident	59 Å²	59	37.8 Å²	37.8	30%	0.303	18%	0.178	S	C	.	.	H	α-helix	trans	-65.1	-45.5	-179.6	-59.5	173.3	0	0	0	110.1	V93 C363 I364 N365 L369 Y370 F371	V93-I367 HydrophobicContact CG1-CD1 3.92Å; C363-I367 WeakPolarHBondContact O-CD1 3.38Å; C363-I367 WeakPolarHBondContact O-CG1 3.42Å; I364-I367 CarbonylContact O-C 3.58Å; I364-I367 WeakPolarHBondContact O-CA 3.4Å; I364-I367 WeakPolarHBondContact O-CB 3.47Å; I364-I367 PolarHBondContact O-N 3.24Å; N365-I367 VanDerWaalsContact C-N 3.32Å; N365-I367 PolarHBondContact O-N 2.58Å; I367-L369 VanDerWaalsContact C-N 3.34Å; I367-L369 PolarHBondContact O-N 2.93Å; I367-Y370 WeakPolarHBondContact O-CB 3.01Å; I367-Y370 PolarHBondContact O-N 3.04Å; I367-F371 HydrophobicContact CG2-CD2 3.72Å; I367-F371 HydrophobicContact CG2-CE2 3.58Å; I367-F371 WeakPolarHBondContact O-CD2 3.12Å; I367-F371 PolarHBondContact O-N 3.16Å
368	A	84.8	Confident	84.4	Confident	5 Å²	5	40.9 Å²	40.9	4%	0.041	20%	0.195	C	C	.	.	H	α-helix	trans	-61.3	-43.9	176.3	0	0	0	0	0	111.1	L311 I314 I364 N365 Y370 F371 V372	L311-A368 HydrophobicContact CD2-CB 3.54Å; I314-A368 HydrophobicContact CD1-CB 3.65Å; I364-A368 HydrophobicContact CG2-CB 4.45Å; I364-A368 WeakPolarHBondContact O-CB 3.23Å; I364-A368 PolarHBondContact O-N 3.1Å; N365-A368 PolarHBondContact O-N 2.86Å; A368-Y370 VanDerWaalsContact C-N 3.33Å; A368-Y370 PolarHBondContact O-N 3.5Å; A368-F371 PolarHBondContact O-N 3.33Å; A368-V372 WeakPolarHBondContact O-CB 3.45Å; A368-V372 VanDerWaalsContact O-CG2 3.25Å; A368-V372 WeakPolarHBondContact O-CG2 3.45Å; A368-V372 PolarHBondContact O-N 3.41Å
369	L	84.3	Confident	84.2	Confident	5 Å²	5	41.8 Å²	41.8	3%	0.026	20%	0.2	C	C	.	.	H	α-helix	trans	-63.2	-37.8	175.8	-70.7	171.3	0	0	0	112.6	L101 I119 T307 L311 N365 P366 I367 S373 F376	L101-L369 HydrophobicContact CD1-CD1 4.09Å; L101-L369 HydrophobicContact CD2-CD1 3.69Å; I119-L369 HydrophobicContact CD1-CD2 4.17Å; I119-L369 HydrophobicContact CG2-CD1 3.55Å; T307-L369 HydrophobicContact CG2-CD2 3.98Å; L311-L369 HydrophobicContact CD1-CD2 4.39Å; N365-L369 WeakPolarHBondContact O-CG 3.28Å; N365-L369 PolarHBondContact O-N 3.24Å; P366-L369 PolarHBondContact O-N 3.14Å; I367-L369 VanDerWaalsContact C-N 3.34Å; I367-L369 PolarHBondContact O-N 2.93Å; L369-S373 WeakPolarHBondContact O-CB 3.38Å; L369-S373 PolarHBondContact O-N 3.34Å; L369-F376 HydrophobicContact CB-CG 4.47Å; L369-F376 HydrophobicContact CD2-CD2 4.35Å; L369-F376 HydrophobicContact CD2-CE2 4.36Å
370	Y	86.4	Confident	84.3	Confident	61 Å²	61	42 Å²	42	24%	0.239	20%	0.201	C	C	.	.	H	α-helix	trans	-60.9	-45.3	174.4	175.8	-95.8	0	0	0	112.4	P366 I367 A368 K377 F380 Q381	P366-Y370 WeakPolarHBondContact O-CB 3.45Å; P366-Y370 PolarHBondContact O-N 3.24Å; I367-Y370 WeakPolarHBondContact O-CB 3.01Å; I367-Y370 PolarHBondContact O-N 3.04Å; A368-Y370 VanDerWaalsContact C-N 3.33Å; A368-Y370 PolarHBondContact O-N 3.5Å; Y370-K377 HydrophobicContact CD2-CB 4.39Å; Y370-K377 HydrophobicContact CD2-CG 4.07Å; Y370-K377 HydrophobicContact CE1-CG 4.41Å; Y370-K377 HydrophobicContact CE2-CB 4.42Å; Y370-K377 HydrophobicContact CE2-CG 3.67Å; Y370-K377 VanDerWaalsContact O-CB 3.31Å; Y370-K377 WeakPolarHBondContact O-CB 3.49Å; Y370-F380 HydrophobicContact CD2-CB 3.56Å; Y370-F380 HydrophobicContact CD2-CD2 4.01Å; Y370-F380 AromaticContact CD2-CG 4Å; Y370-F380 HydrophobicContact CD2-CG 4Å; Y370-F380 HydrophobicContact CE2-CB 3.95Å; Y370-Q381 HydrophobicContact CE2-CG 4.01Å; Y370-Q381 PolarHBondContact OH-NE2 2.87Å
371	F	81.1	Confident	84.2	Confident	129 Å²	129	44.5 Å²	44.5	57%	0.566	21%	0.213	S	C	*	.	H	α-helix	trans	-78.7	-34.4	-177.1	-77	-67.3	0	0	0	113.7	I367 A368	I367-F371 HydrophobicContact CG2-CD2 3.72Å; I367-F371 HydrophobicContact CG2-CE2 3.58Å; I367-F371 WeakPolarHBondContact O-CD2 3.12Å; I367-F371 PolarHBondContact O-N 3.16Å; A368-F371 PolarHBondContact O-N 3.33Å
372	V	73.3	Confident	84	Confident	35 Å²	35	48.1 Å²	48.1	21%	0.212	24%	0.238	C	C	.	.	H	α-helix	trans	-90.9	-33.1	-173.2	-165.7	0	0	0	0	112.5	T307 A368	T307-V372 HydrophobicContact CG2-CB 3.85Å; T307-V372 HydrophobicContact CG2-CG1 4.02Å; T307-V372 HydrophobicContact CG2-CG2 4.49Å; T307-V372 WeakPolarHBondContact OG1-CG1 3.23Å; A368-V372 WeakPolarHBondContact O-CB 3.45Å; A368-V372 VanDerWaalsContact O-CG2 3.25Å; A368-V372 WeakPolarHBondContact O-CG2 3.45Å; A368-V372 PolarHBondContact O-N 3.41Å
373	S	79.5	Confident	83.7	Confident	23 Å²	23	49.5 Å²	49.5	16%	0.161	25%	0.248	C	C	.	.			trans	-105	112.2	-178.8	176.1	0	0	0	0	112.3	L369 K375 F376 K377	L369-S373 WeakPolarHBondContact O-CB 3.38Å; L369-S373 PolarHBondContact O-N 3.34Å; S373-K375 PolarHBondContact O-N 2.86Å; S373-K375 VanDerWaalsContact O-N 3.15Å; S373-K375 PolarHBondContact OG-N 2.97Å; S373-F376 PolarHBondContact O-N 3.16Å; S373-F376 VanDerWaalsContact O-N 3.13Å; S373-F376 WeakPolarHBondContact OG-CD2 3.45Å; S373-F376 PolarHBondContact OG-N 3.45Å; S373-K377 WeakPolarHBondContact O-CB 3.26Å; S373-K377 PolarHBondContact O-N 2.69Å
374	K	78.8	Confident	83.2	Confident	178 Å²	178	53.7 Å²	53.7	77%	0.774	27%	0.269	S	S	*	.	H	α-helix	trans	-52.6	-36.9	172.7	-68.1	-176.1	179.2	-177.8	0	112.5	N378	K374-N378 PolarHBondContact O-N 3.34Å; K374-N378 PolarHBondContact O-OD1 3.28Å
375	K	80.8	Confident	82.4	Confident	103 Å²	103	55.5 Å²	55.5	45%	0.448	28%	0.283	S	S	.	.	H	α-helix	trans	-66.9	-47.4	179.6	-164.8	179.4	-172.8	-163.5	0	111.2	C110 M111 S373 C379	C110-K375 PolarHBondContact O-NZ 2.88Å; M111-K375 HydrophobicContact CE-CD 4.34Å; M111-K375 HydrophobicContact CE-CG 4.37Å; M111-K375 HydrophobicContact SD-CD 3.42Å; M111-K375 WeakPolarHBondContact SD-CD 3.06Å; M111-K375 WeakPolarHBondContact SD-CE 3.31Å; M111-K375 HydrophobicContact SD-CG 3.84Å; M111-K375 PolarHBondContact SD-NZ 3.15Å; S373-K375 PolarHBondContact O-N 2.86Å; S373-K375 VanDerWaalsContact O-N 3.15Å; S373-K375 PolarHBondContact OG-N 2.97Å; K375-C379 PolarHBondContact O-N 3.21Å; K375-C379 PolarHBondContact O-SG 3.45Å
376	F	83.9	Confident	81	Confident	9 Å²	9	59.9 Å²	59.9	4%	0.039	31%	0.313	C	S	.	.	H	α-helix	trans	-66.6	-42.6	175.7	-79.1	-72.5	0	0	0	111.3	L101 I105 M111 N116 I119 L369 S373 N378 C379 F380	L101-F376 HydrophobicContact CD1-CD1 3.85Å; L101-F376 HydrophobicContact CD1-CE1 3.6Å; L101-F376 HydrophobicContact CD1-CZ 4.5Å; I105-F376 HydrophobicContact CD1-CE1 4.4Å; I105-F376 HydrophobicContact CG1-CE1 4.26Å; M111-F376 HydrophobicContact CE-CD1 3.58Å; M111-F376 HydrophobicContact CE-CD2 4.3Å; M111-F376 HydrophobicContact CE-CE1 3.27Å; M111-F376 HydrophobicContact CE-CE2 4.03Å; M111-F376 HydrophobicContact CE-CG 4.09Å; M111-F376 HydrophobicContact CE-CZ 3.51Å; N116-F376 WeakPolarHBondContact OD1-CZ 3.48Å; I119-F376 HydrophobicContact CD1-CE2 4.01Å; I119-F376 HydrophobicContact CD1-CZ 3.97Å; L369-F376 HydrophobicContact CB-CG 4.47Å; L369-F376 HydrophobicContact CD2-CD2 4.35Å; L369-F376 HydrophobicContact CD2-CE2 4.36Å; S373-F376 PolarHBondContact O-N 3.16Å; S373-F376 VanDerWaalsContact O-N 3.13Å; S373-F376 WeakPolarHBondContact OG-CD2 3.45Å; S373-F376 PolarHBondContact OG-N 3.45Å; F376-N378 VanDerWaalsContact C-N 3.33Å; F376-N378 PolarHBondContact O-N 3.26Å; F376-C379 PolarHBondContact O-N 3.43Å; F376-C379 VanDerWaalsContact O-N 3.13Å; F376-F380 HydrophobicContact CB-CD2 4.15Å; F376-F380 HydrophobicContact CB-CE2 4.16Å; F376-F380 HydrophobicContact CD1-CE2 4.42Å; F376-F380 WeakPolarHBondContact O-CD2 3.49Å; F376-F380 PolarHBondContact O-N 2.89Å
377	K	85.8	Confident	79.1	Confident	83 Å²	83	65.8 Å²	65.8	36%	0.361	35%	0.353	S	S	.	.	H	α-helix	trans	-49.3	-53.1	175	-170	-178.1	174.7	179.7	0	112	Y370 S373 C379 F380 Q381	Y370-K377 HydrophobicContact CD2-CB 4.39Å; Y370-K377 HydrophobicContact CD2-CG 4.07Å; Y370-K377 HydrophobicContact CE1-CG 4.41Å; Y370-K377 HydrophobicContact CE2-CB 4.42Å; Y370-K377 HydrophobicContact CE2-CG 3.67Å; Y370-K377 VanDerWaalsContact O-CB 3.31Å; Y370-K377 WeakPolarHBondContact O-CB 3.49Å; S373-K377 WeakPolarHBondContact O-CB 3.26Å; S373-K377 PolarHBondContact O-N 2.69Å; K377-C379 VanDerWaalsContact C-N 3.34Å; K377-C379 PolarHBondContact O-N 3.03Å; K377-F380 PolarHBondContact O-N 2.98Å; K377-Q381 WeakPolarHBondContact O-CG 3.05Å; K377-Q381 PolarHBondContact O-N 3.4Å
378	N	84.5	Confident	76.9	Confident	93 Å²	93	68 Å²	68	50%	0.497	37%	0.373	S	S	.	.	H	α-helix	trans	-62.1	-42.7	-178.8	-67.1	-3.4	0	0	0	111.3	K374 F376 Q381 S382	K374-N378 PolarHBondContact O-N 3.34Å; K374-N378 PolarHBondContact O-OD1 3.28Å; F376-N378 VanDerWaalsContact C-N 3.33Å; F376-N378 PolarHBondContact O-N 3.26Å; N378-Q381 PolarHBondContact O-N 3.48Å; N378-S382 PolarHBondContact O-N 3.33Å; N378-S382 PolarHBondContact O-OG 2.97Å
379	C	84.9	Confident	74.6	Confident	21 Å²	21	74.6 Å²	74.6	14%	0.142	40%	0.402	C	S	.	.	H	α-helix	trans	-66.1	-40.1	177	-63.2	0	0	0	0	112.9	I104 K375 F376 K377 S382 C383	I104-C379 HydrophobicContact CB-CB 4.41Å; I104-C379 HydrophobicContact CD1-CB 3.92Å; I104-C379 HydrophobicContact CG1-CB 4.03Å; I104-C379 HydrophobicContact CG2-CB 3.48Å; I104-C379 VanDerWaalsContact CG2-CB 3.48Å; K375-C379 PolarHBondContact O-N 3.21Å; K375-C379 PolarHBondContact O-SG 3.45Å; F376-C379 PolarHBondContact O-N 3.43Å; F376-C379 VanDerWaalsContact O-N 3.13Å; K377-C379 VanDerWaalsContact C-N 3.34Å; K377-C379 PolarHBondContact O-N 3.03Å; C379-S382 PolarHBondContact O-N 3.28Å; C379-C383 WeakPolarHBondContact O-CB 3.48Å; C379-C383 PolarHBondContact O-N 2.98Å
380	F	85.7	Confident	72.4	Confident	7 Å²	7	84.3 Å²	84.3	3%	0.031	45%	0.447	C	S	.	.	H	α-helix	trans	-63.1	-43.3	174.3	-85.1	-68.7	0	0	0	111.5	T100 L101 I104 P366 Y370 F376 K377 C383 L384	T100-F380 HydrophobicContact CG2-CD1 3.66Å; T100-F380 HydrophobicContact CG2-CE1 3.79Å; L101-F380 HydrophobicContact CB-CE1 4.48Å; L101-F380 HydrophobicContact CB-CZ 4Å; L101-F380 HydrophobicContact CD1-CE2 4.28Å; L101-F380 HydrophobicContact CD1-CZ 3.98Å; I104-F380 HydrophobicContact CD1-CB 4.34Å; I104-F380 HydrophobicContact CD1-CD1 3.64Å; I104-F380 HydrophobicContact CD1-CD2 4.12Å; I104-F380 HydrophobicContact CD1-CE1 3.9Å; I104-F380 HydrophobicContact CD1-CE2 4.35Å; I104-F380 HydrophobicContact CD1-CG 3.75Å; I104-F380 HydrophobicContact CD1-CZ 4.25Å; P366-F380 HydrophobicContact CB-CZ 4.13Å; Y370-F380 HydrophobicContact CD2-CB 3.56Å; Y370-F380 HydrophobicContact CD2-CD2 4.01Å; Y370-F380 AromaticContact CD2-CG 4Å; Y370-F380 HydrophobicContact CD2-CG 4Å; Y370-F380 HydrophobicContact CE2-CB 3.95Å; F376-F380 HydrophobicContact CB-CD2 4.15Å; F376-F380 HydrophobicContact CB-CE2 4.16Å; F376-F380 HydrophobicContact CD1-CE2 4.42Å; F376-F380 WeakPolarHBondContact O-CD2 3.49Å; F376-F380 PolarHBondContact O-N 2.89Å; K377-F380 PolarHBondContact O-N 2.98Å; F380-C383 PolarHBondContact O-N 3.07Å; F380-L384 HydrophobicContact CD1-CD1 4.24Å; F380-L384 VanDerWaalsContact O-CB 3.31Å; F380-L384 WeakPolarHBondContact O-CB 3.15Å; F380-L384 WeakPolarHBondContact O-CG 3.36Å; F380-L384 PolarHBondContact O-N 2.92Å
381	Q	85.5	Confident	70	Confident	75 Å²	75	85.3 Å²	85.3	35%	0.35	46%	0.464	S	S	.	.	H	α-helix	trans	-62.9	-42.9	175.1	-71.6	179.2	-33.3	0	0	111.4	Y370 K377 N378 C385	Y370-Q381 HydrophobicContact CE2-CG 4.01Å; Y370-Q381 PolarHBondContact OH-NE2 2.87Å; K377-Q381 WeakPolarHBondContact O-CG 3.05Å; K377-Q381 PolarHBondContact O-N 3.4Å; N378-Q381 PolarHBondContact O-N 3.48Å; Q381-C385 WeakPolarHBondContact O-CA 3.25Å; Q381-C385 WeakPolarHBondContact O-CB 3.26Å; Q381-C385 PolarHBondContact O-N 3.36Å
382	S	82.4	Confident	68.2	Low	76 Å²	76	89.1 Å²	89.1	53%	0.531	48%	0.48	S	S	.	.	H	α-helix	trans	-60.7	-46.5	173.2	-65	0	0	0	0	112.1	N378 C379 C386	N378-S382 PolarHBondContact O-N 3.33Å; N378-S382 PolarHBondContact O-OG 2.97Å; C379-S382 PolarHBondContact O-N 3.28Å; S382-C386 VanDerWaalsContact O-CB 3.26Å; S382-C386 WeakPolarHBondContact O-CB 3.19Å; S382-C386 PolarHBondContact O-N 3.3Å; S382-C386 PolarHBondContact O-SG 3.14Å
383	C	80.4	Confident	66.4	Low	35 Å²	35	92.7 Å²	92.7	24%	0.236	51%	0.506	C	S	.	.	H	α-helix	trans	-72.7	-39.1	-176.9	-74.7	0	0	0	0	114.1	T100 I104 C379 F380	T100-C383 HydrophobicContact CG2-CB 4.01Å; I104-C383 HydrophobicContact CG1-CB 4.42Å; C379-C383 WeakPolarHBondContact O-CB 3.48Å; C379-C383 PolarHBondContact O-N 2.98Å; F380-C383 PolarHBondContact O-N 3.07Å
384	L	78.3	Confident	64.3	Low	96 Å²	96	99 Å²	99	50%	0.503	54%	0.537	S	S	.	.	H	α-helix	trans	-90	-36	-175.6	-63.4	172.4	0	0	0	112.5	V96 T100 F380 C386	V96-L384 HydrophobicContact CG1-CD2 4.27Å; T100-L384 HydrophobicContact CG2-CD2 4.22Å; T100-L384 HydrophobicContact CG2-CG 4.27Å; F380-L384 HydrophobicContact CD1-CD1 4.24Å; F380-L384 VanDerWaalsContact O-CB 3.31Å; F380-L384 WeakPolarHBondContact O-CB 3.15Å; F380-L384 WeakPolarHBondContact O-CG 3.36Å; F380-L384 PolarHBondContact O-N 2.92Å; L384-C386 VanDerWaalsContact C-N 3.35Å
385	C	70.5	Confident	62.3	Low	65 Å²	65	96.8 Å²	96.8	44%	0.439	53%	0.531	S	S	.	.	S	Bend	trans	-93.8	13.4	179.7	-50.1	0	0	0	0	113	Q381 C387 C388 H389	Q381-C385 WeakPolarHBondContact O-CA 3.25Å; Q381-C385 WeakPolarHBondContact O-CB 3.26Å; Q381-C385 PolarHBondContact O-N 3.36Å; C385-C387 PolarHBondContact O-N 2.04Å; C385-C388 PolarHBondContact O-N 2.76Å; C385-H389 PolarHBondContact O-N 3.06Å
386	C	55.9	Low	59.9	Low	96 Å²	96	96.7 Å²	96.7	65%	0.649	54%	0.54	S	S	*	.	T	Hydrogen-bonded Turn	trans	-59.8	-13.4	175.2	-113.9	0	0	0	0	113.5	S382 L384 C388	S382-C386 VanDerWaalsContact O-CB 3.26Å; S382-C386 WeakPolarHBondContact O-CB 3.19Å; S382-C386 PolarHBondContact O-N 3.3Å; S382-C386 PolarHBondContact O-SG 3.14Å; L384-C386 VanDerWaalsContact C-N 3.35Å; C386-C388 VanDerWaalsContact C-N 3.35Å
387	C	46.7	Very low	57.4	Low	127 Å²	127	101.7 Å²	101.7	86%	0.858	58%	0.576	S	S	*	*	T	Hydrogen-bonded Turn	trans	-79.8	-12.3	169.9	-59.6	0	0	0	0	113.7	C385	C385-C387 PolarHBondContact O-N 2.04Å
388	C	42.4	Very low	54.9	Low	107 Å²	107	103.6 Å²	103.6	72%	0.723	59%	0.594	S	S	*	*	T	Hydrogen-bonded Turn	trans	-129.8	-6.3	-171.1	-57	0	0	0	0	115.3	C385 C386	C385-C388 PolarHBondContact O-N 2.76Å; C386-C388 VanDerWaalsContact C-N 3.35Å
389	H	36.5	Very low	52.3	Low	142 Å²	142	104.9 Å²	104.9	66%	0.657	61%	0.607	S	S	*	*			trans	-151	82.2	-179.2	-136.9	60.6	0	0	0	113.7	C385 S391	C385-H389 PolarHBondContact O-N 3.06Å; H389-S391 VanDerWaalsContact CD2-CB 3.4Å; H389-S391 WeakPolarHBondContact CD2-CB 3.46Å; H389-S391 WeakPolarHBondContact NE2-CB 3.42Å; H389-S391 PolarHBondContact O-N 3.47Å
390	Q	37.9	Very low	49.8	Very low	209 Å²	209	112.3 Å²	112.3	98%	0.977	64%	0.642	S	S	*	*			trans	-77.7	76.1	158.1	-151	176.6	37.6	0	0	107.7
391	S	36.1	Very low	47.5	Very low	83 Å²	83	120.4 Å²	120.4	58%	0.58	69%	0.686	S	S	*	*			trans	-116.2	129	169.6	-163.7	0	0	0	0	110.5	H389 S393	H389-S391 VanDerWaalsContact CD2-CB 3.4Å; H389-S391 WeakPolarHBondContact CD2-CB 3.46Å; H389-S391 WeakPolarHBondContact NE2-CB 3.42Å; H389-S391 PolarHBondContact O-N 3.47Å; S391-S393 PolarHBondContact O-N 2.87Å
392	K	42.5	Very low	45.1	Very low	209 Å²	209	119.7 Å²	119.7	91%	0.909	70%	0.699	S	S	*	*			trans	-57.5	116.6	-164.6	-65.3	164.4	177.5	174.6	0	112.3
393	S	36.4	Very low	43	Very low	110 Å²	110	123.6 Å²	123.6	77%	0.769	72%	0.72	S	S	*	*			trans	-145.4	70.7	153.1	179.6	0	0	0	0	108.3	S391 M395	S391-S393 PolarHBondContact O-N 2.87Å; S393-M395 PolarHBondContact O-N 3.19Å
394	L	35.4	Very low	40.7	Very low	154 Å²	154	126.9 Å²	126.9	81%	0.806	74%	0.743	S	S	*	*			trans	-75.3	99.7	165.1	-162.8	78.6	0	0	0	106.1	T396	L394-T396 PolarHBondContact O-N 3.38Å; L394-T396 PolarHBondContact O-OG1 3.25Å; L394-T396 VanDerWaalsContact O-OG1 3.13Å
395	M	35.4	Very low	38.7	Very low	132 Å²	132	129.4 Å²	129.4	65%	0.65	76%	0.756	S	S	*	*			trans	-66.5	88.7	174.3	-152.9	163.8	79.9	0	0	107.8	S393 W407	S393-M395 PolarHBondContact O-N 3.19Å; M395-W407 HydrophobicContact CE-CH2 3.65Å; M395-W407 HydrophobicContact CE-CZ3 3.4Å; M395-W407 VanDerWaalsContact CE-CZ3 3.4Å; M395-W407 HydrophobicContact SD-CZ3 3.87Å
396	T	30.6	Very low	36.8	Very low	102 Å²	102	135 Å²	135	63%	0.626	78%	0.775	S	S	*	*			trans	-89.6	111.5	-177.3	-47.7	0	0	0	0	107.8	L394 V398	L394-T396 PolarHBondContact O-N 3.38Å; L394-T396 PolarHBondContact O-OG1 3.25Å; L394-T396 VanDerWaalsContact O-OG1 3.13Å; T396-V398 PolarHBondContact O-N 3.49Å
397	S	31.6	Very low	35.6	Very low	113 Å²	113	138.8 Å²	138.8	79%	0.79	78%	0.776	S	S	*	*			trans	-75.1	114	170.7	54.6	0	0	0	0	109.2
398	V	33.2	Very low	34.6	Very low	123 Å²	123	142.2 Å²	142.2	75%	0.745	78%	0.776	S	S	*	*			trans	-85.3	125.2	167.3	-179.4	0	0	0	0	108	T396	T396-V398 PolarHBondContact O-N 3.49Å
399	P	30	Very low	33.9	Very low	120 Å²	120	144.3 Å²	144.3	78%	0.779	78%	0.78	S	S	*	*			trans	-82.1	128.5	171.8	31.5	-27.1	0	0	0	109.3
400	M	32.5	Very low	33.4	Very low	178 Å²	178	145.8 Å²	145.8	88%	0.877	79%	0.787	S	S	*	*			trans	-133.6	142.1	157.2	-89.1	-129.4	167.8	0	0	109.8
401	N	36.6	Very low	33	Very low	176 Å²	176	142.3 Å²	142.3	94%	0.941	78%	0.775	S	S	*	*	S	Bend	trans	-53.9	131.7	-174.5	-77.8	-19.2	0	0	0	112.8
402	G	35.4	Very low	32.6	Very low	61 Å²	61	147 Å²	147	63%	0.629	79%	0.788	S	S	*	*	S	Bend	trans	128.5	124.2	173.4	0	0	0	0	0	112	S404	G402-S404 VanDerWaalsContact C-N 3.29Å; G402-S404 PolarHBondContact O-N 3.12Å
403	T	39	Very low	31.8	Very low	158 Å²	158	143.9 Å²	143.9	97%	0.969	78%	0.781	S	S	*	*	S	Bend	trans	-65.4	69.9	-174.7	32.9	0	0	0	0	114.3
404	S	32.8	Very low	31.4	Very low	104 Å²	104	146.1 Å²	146.1	73%	0.727	78%	0.784	S	S	*	*			trans	-161.7	123.1	159.8	58.5	0	0	0	0	111.6	G402	G402-S404 VanDerWaalsContact C-N 3.29Å; G402-S404 PolarHBondContact O-N 3.12Å
405	I	35.4	Very low	31.1	Very low	149 Å²	149	147 Å²	147	76%	0.764	78%	0.784	S	S	*	*			trans	-97.5	104.4	174.3	-58.3	175.3	0	0	0	107.9
406	Q	30.5	Very low	30.7	Very low	183 Å²	183	147.8 Å²	147.8	86%	0.855	79%	0.791	S	S	*	*			trans	-100.4	123.2	171.8	-165.2	173.8	9.2	0	0	109.8
407	W	31	Very low	30.6	Very low	175 Å²	175	149.1 Å²	149.1	66%	0.663	80%	0.799	S	S	*	*			trans	-86.8	109.7	177.7	-66.7	78.1	0	0	0	109.3	M395	M395-W407 HydrophobicContact CE-CH2 3.65Å; M395-W407 HydrophobicContact CE-CZ3 3.4Å; M395-W407 VanDerWaalsContact CE-CZ3 3.4Å; M395-W407 HydrophobicContact SD-CZ3 3.87Å
408	K	25.3	Very low	30.4	Very low	198 Å²	198	153.2 Å²	153.2	86%	0.861	81%	0.806	S	S	*	*			trans	-97.1	114.8	174.4	-155.8	174.7	-175.1	-179.7	0	108.6	H410	K408-H410 PolarHBondContact O-N 3.48Å
409	N	27.2	Very low	30.1	Very low	151 Å²	151	158.8 Å²	158.8	81%	0.807	81%	0.814	S	S	*	*			trans	-68.1	119	164	-80.7	-22	0	0	0	107.1	D411	N409-D411 PolarHBondContact O-N 2.8Å
410	H	27.1	Very low	30.1	Very low	173 Å²	173	158.1 Å²	158.1	80%	0.801	81%	0.811	S	S	*	*			trans	-85.5	97	168.9	-151.3	-50.5	0	0	0	107.4	K408 Q412	K408-H410 PolarHBondContact O-N 3.48Å; H410-Q412 PolarHBondContact O-N 2.98Å
411	D	28.4	Very low	29.9	Very low	137 Å²	137	155 Å²	155	73%	0.733	81%	0.807	S	S	*	*			trans	-65.9	127.9	160.4	-76.9	-37.1	0	0	0	107.5	N409 N413	N409-D411 PolarHBondContact O-N 2.8Å; D411-N413 PolarHBondContact O-N 2.92Å; D411-N413 VanDerWaalsContact O-N 3.13Å
412	Q	27.8	Very low	29.6	Very low	182 Å²	182	154.7 Å²	154.7	85%	0.85	80%	0.8	S	S	*	*			trans	-75.5	92.1	175.5	-111.1	172.4	-23.7	0	0	108.2	H410 N414	H410-Q412 PolarHBondContact O-N 2.98Å; Q412-N414 PolarHBondContact O-N 3.35Å
413	N	26	Very low	29.3	Very low	143 Å²	143	161.7 Å²	161.7	77%	0.765	81%	0.813	S	S	*	*			trans	-81	110.3	159.4	-98.1	1.1	0	0	0	108.2	D411 H415	D411-N413 PolarHBondContact O-N 2.92Å; D411-N413 VanDerWaalsContact O-N 3.13Å; N413-H415 PolarHBondContact O-N 3.37Å; N413-H415 VanDerWaalsContact O-N 3.09Å
414	N	28.6	Very low	29	Very low	156 Å²	156	160.7 Å²	160.7	83%	0.834	80%	0.802	S	S	*	*			trans	-60	104.9	163	-95.9	-8	0	0	0	108.6	Q412	Q412-N414 PolarHBondContact O-N 3.35Å
415	H	27.9	Very low	29	Very low	174 Å²	174	161 Å²	161	81%	0.806	80%	0.804	S	S	*	*			trans	-93.6	104.4	158.8	-106.6	-63.6	0	0	0	108.3	N413	N413-H415 PolarHBondContact O-N 3.37Å; N413-H415 VanDerWaalsContact O-N 3.09Å
416	N	28.5	Very low	28.8	Very low	148 Å²	148	163.1 Å²	163.1	79%	0.791	81%	0.813	S	S	*	*			trans	-67	127.5	153.3	-85.3	-13.8	0	0	0	108.1
417	T	28.9	Very low	29	Very low	129 Å²	129	165.8 Å²	165.8	79%	0.791	83%	0.833	S	S	*	*			trans	-29.1	123.1	161.5	-35.2	0	0	0	0	113.7
418	E	26.6	Very low	28.9	Very low	199 Å²	199	165.3 Å²	165.3	93%	0.93	84%	0.841	S	S	*	*				-160.8	147.7	129.8	-115.1	174.9	-179.1	0	0	112.1
419	R	27.1	Very low	29.1	Very low	241 Å²	241	163.6 Å²	163.6	91%	0.909	84%	0.84	S	S	*	*			trans	-115.6	116.4	-157.3	171.7	-171.3	-173.2	179.2	2.1	107
420	S	28.6	Very low	29.2	Very low	105 Å²	105	164.3 Å²	164.3	73%	0.734	84%	0.842	S	S	*	*			trans	-160.3	101.3	158.7	62.9	0	0	0	0	113
421	S	29.1	Very low	29.3	Very low	113 Å²	113	163.8 Å²	163.8	79%	0.79	85%	0.845	S	S	*	*			trans	43.5	115.4	130.1	47.1	0	0	0	0	120.9
422	H	29.5	Very low	29.3	Very low	170 Å²	170	165.4 Å²	165.4	79%	0.787	85%	0.852	S	S	*	*			trans	-24.1	137.4	150.2	-84.9	-86.1	0	0	0	116.4	D424	H422-D424 IonicContact ND1-OD2 3.48Å; H422-D424 PolarHBondContact ND1-OD2 3.11Å
423	K	29.8	Very low	29.4	Very low	207 Å²	207	164.3 Å²	164.3	90%	0.9	85%	0.852	S	S	*	*			trans	-150.6	104.5	133.6	-119.3	178.3	-179.5	-179.2	0	109.9
424	D	32.3	Very low	29.7	Very low	137 Å²	137	165.9 Å²	165.9	73%	0.733	86%	0.858	S	S	*	*			trans	-76.9	135.6	160.6	-69.2	-61	0	0	0	109.1	H422	H422-D424 IonicContact ND1-OD2 3.48Å; H422-D424 PolarHBondContact ND1-OD2 3.11Å
425	S	32.5	Very low	29.8	Very low	112 Å²	112	166.6 Å²	166.6	78%	0.783	86%	0.86	S	S	*	*			trans	-166.3	97.9	149.7	55.8	0	0	0	0	110.4
426	M	32.5	Very low	29.9	Very low	193 Å²	193	166 Å²	166	95%	0.951	86%	0.864	S	S	*	*			trans	-97.8	105.7	145.5	-88.3	173.5	113.7	0	0	106.9
427	N	34	Very low	30.1	Very low	238 Å²	238	167.6 Å²	167.6	100%	1.273	87%	0.871	S	S	*	*			trans	-179.2	0	137.4	-100.4	0.8	0	0	0	109.1

Retrieved 427 of 427 residues in 88.6 ms (Link to these results)

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