A0A061IAY6_CRIGR Loading...

Protein spinster homolog 1

AlphaFold DB , UniProt , Accession A0A061IAY6, Species CRIGR (Cricetulus griseus, Chinese hamster), Gene Spns1, Length 528 aa.

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	34.5	Very low	28	Very low	244 Å²	244	129.9 Å²	129.9	100%	1.202	81%	0.805	S	S	*	*				0	81.9	0	-68.3	172.4	169.2	0	0	105.9
2	A	23.9	Very low	27.9	Very low	106 Å²	106	133.6 Å²	133.6	88%	0.876	81%	0.805	S	S	*	*				55.9	93.6	54.4	0	0	0	0	0	112.9
3	G	24.1	Very low	28	Very low	71 Å²	71	131.2 Å²	131.2	73%	0.732	81%	0.809	S	S	*	*				98.9	153.4	117.3	0	0	0	0	0	119.7
4	S	25.2	Very low	28.1	Very low	108 Å²	108	131.7 Å²	131.7	76%	0.755	80%	0.804	S	S	*	*			trans	93.7	105.6	165.5	75.8	0	0	0	0	115.2
5	D	27.5	Very low	28.2	Very low	147 Å²	147	132.9 Å²	132.9	79%	0.786	80%	0.803	S	S	*	*				98.8	126.2	60.2	-83.3	-32.1	0	0	0	110
6	T	28.5	Very low	29.1	Very low	136 Å²	136	131.2 Å²	131.2	83%	0.834	80%	0.796	S	S	*	*				156.7	114.3	115.9	42.9	0	0	0	0	111.1
7	A	28.3	Very low	29.2	Very low	88 Å²	88	132.1 Å²	132.1	73%	0.727	80%	0.795	S	S	*	*			trans	-65.5	170.7	150.2	0	0	0	0	0	108.5
8	P	39.3	Very low	29.3	Very low	105 Å²	105	133.8 Å²	133.8	68%	0.682	80%	0.8	S	S	*	*				-168.7	-174.3	62	42.3	-17.8	0	0	0	119.5
9	F	24.1	Very low	29.2	Very low	180 Å²	180	130.7 Å²	130.7	79%	0.789	80%	0.798	S	S	*	*			trans	97.4	112.4	133	-93.2	-66	0	0	0	123.8
10	L	26.1	Very low	29.4	Very low	136 Å²	136	130.6 Å²	130.6	71%	0.712	80%	0.8	S	S	*	*			trans	57.2	132.9	135	-82.8	171.9	0	0	0	125.5
11	S	27	Very low	29.5	Very low	108 Å²	108	129.1 Å²	129.1	76%	0.755	80%	0.801	S	S	*	*				169.7	116.2	105.4	44.4	0	0	0	0	110
12	Q	26.6	Very low	29.2	Very low	174 Å²	174	123.7 Å²	123.7	81%	0.813	79%	0.787	S	S	*	*				60.2	118.2	90.9	-93.1	-169.7	-14.4	0	0	116.3
13	A	29.5	Very low	29.3	Very low	103 Å²	103	121.8 Å²	121.8	85%	0.851	78%	0.778	S	S	*	*				-175.6	138.9	120.5	0	0	0	0	0	111.4
14	D	28.6	Very low	29.5	Very low	138 Å²	138	127.4 Å²	127.4	74%	0.738	79%	0.785	S	S	*	*			trans	-87.5	154.6	-169.7	-58.7	-57.2	0	0	0	114.7
15	D	29.6	Very low	30.2	Very low	149 Å²	149	127.9 Å²	127.9	80%	0.797	79%	0.786	S	S	*	*			trans	51.8	168.2	132.9	-78.1	-16.1	0	0	0	122.9
16	P	43.5	Very low	30.1	Very low	106 Å²	106	124.2 Å²	124.2	69%	0.688	78%	0.783	S	S	*	*			cis	-138.5	170.8	-2.5	19.2	7.5	0	0	0	117.4
17	D	29.6	Very low	30.2	Very low	146 Å²	146	126.3 Å²	126.3	78%	0.781	79%	0.787	S	S	*	*			trans	38.1	129.4	141.7	-74.1	-33	0	0	0	124.4
18	D	31.8	Very low	30.1	Very low	164 Å²	164	127.9 Å²	127.9	88%	0.877	79%	0.793	S	S	*	*				177.2	128.8	99.8	-105.1	-28.8	0	0	0	114.2
19	G	27.8	Very low	29.6	Very low	75 Å²	75	126 Å²	126	77%	0.773	79%	0.793	S	S	*	*			trans	112.8	128.7	140.4	0	0	0	0	0	120.7
20	P	33.2	Very low	30.1	Very low	127 Å²	127	123.7 Å²	123.7	83%	0.825	80%	0.796	S	S	*	*			trans	-114	155.7	-163.7	38.5	-25	0	0	0	118
21	A	30.1	Very low	30.5	Very low	101 Å²	101	125.9 Å²	125.9	84%	0.835	81%	0.808	S	S	*	*			trans	62.6	121.4	139.5	0	0	0	0	0	124.1
22	S	29.2	Very low	30.5	Very low	129 Å²	129	123.9 Å²	123.9	90%	0.902	80%	0.804	S	S	*	*				-172.9	139.2	123.2	55.3	0	0	0	0	108.1
23	G	25.7	Very low	30.6	Very low	67 Å²	67	122.7 Å²	122.7	69%	0.691	80%	0.803	S	S	*	*			cis	160.8	90.9	0.6	0	0	0	0	0	109.6
24	H	29.1	Very low	30.8	Very low	189 Å²	189	123.6 Å²	123.6	88%	0.875	80%	0.801	S	S	*	*			trans	61.6	163.6	152	-73	-60.6	0	0	0	123.3
25	P	38.7	Very low	31	Very low	118 Å²	118	126 Å²	126	77%	0.766	81%	0.805	S	S	*	*			cis	-135.7	146.4	-17.5	27.8	-6.1	0	0	0	116.4
26	G	25.1	Very low	31.2	Very low	70 Å²	70	123.7 Å²	123.7	72%	0.722	80%	0.8	S	S	*	*				69.9	107.7	123.8	0	0	0	0	0	121.3
27	L	30.5	Very low	30.8	Very low	179 Å²	179	122.1 Å²	122.1	94%	0.937	80%	0.803	S	S	*	*				-161.8	110.1	119.2	-105.5	146.4	0	0	0	110.6
28	S	27.2	Very low	31.1	Very low	122 Å²	122	123.3 Å²	123.3	85%	0.853	80%	0.804	S	S	*	*			trans	-73.4	131.3	173.3	44.3	0	0	0	0	111.7
29	G	28.9	Very low	31.8	Very low	66 Å²	66	122.2 Å²	122.2	68%	0.68	79%	0.793	S	S	*	*			trans	-166.6	135	164.6	0	0	0	0	0	110.4
30	P	33.8	Very low	33	Very low	131 Å²	131	127 Å²	127	85%	0.851	80%	0.796	S	S	*	*			trans	-78.4	143.9	-151.3	-4.8	21.9	0	0	0	112.4	G32	P30-G32 VanDerWaalsContact C-N 3.3Å; P30-G32 PolarHBondContact O-N 3.03Å
31	L	34	Very low	34.4	Very low	181 Å²	181	126.3 Å²	126.3	95%	0.948	78%	0.784	S	S	*	*			trans	-54.9	96.5	158.5	-84.7	94.8	0	0	0	109	N33	L31-N33 PolarHBondContact O-N 2.74Å
32	G	28	Very low	35.9	Very low	67 Å²	67	122.9 Å²	122.9	69%	0.691	75%	0.753	S	S	*	*			trans	-78.1	111.9	164.9	0	0	0	0	0	108.9	P30	P30-G32 VanDerWaalsContact C-N 3.3Å; P30-G32 PolarHBondContact O-N 3.03Å
33	N	28.1	Very low	37.9	Very low	148 Å²	148	121.8 Å²	121.8	79%	0.791	74%	0.737	S	S	*	*			trans	-39.9	129.5	160.5	-108.6	-15.6	0	0	0	110.3	L31 K35	L31-N33 PolarHBondContact O-N 2.74Å; N33-K35 VanDerWaalsContact C-N 3.27Å; N33-K35 PolarHBondContact O-N 3.16Å
34	P	33.3	Very low	40	Very low	123 Å²	123	126.7 Å²	126.7	80%	0.799	74%	0.735	S	S	*	*			trans	-71.2	94.7	164.5	26.3	-22.2	0	0	0	106.5	S36	P34-S36 PolarHBondContact O-N 3.3Å
35	K	34.2	Very low	42	Very low	188 Å²	188	123.7 Å²	123.7	82%	0.817	72%	0.721	S	S	*	*			trans	-56.5	125.9	165.2	-76.1	-174.7	175.8	-177.3	0	107.1	N33 G37	N33-K35 VanDerWaalsContact C-N 3.27Å; N33-K35 PolarHBondContact O-N 3.16Å; K35-G37 PolarHBondContact O-N 3.21Å
36	S	34.2	Very low	43.6	Very low	101 Å²	101	118.9 Å²	118.9	71%	0.706	69%	0.693	S	S	*	*			trans	-30.4	122.5	161.7	46.4	0	0	0	0	111.3	P34 E38	P34-S36 PolarHBondContact O-N 3.3Å; S36-E38 PolarHBondContact O-N 2.87Å
37	G	33.6	Very low	45.8	Very low	73 Å²	73	116.6 Å²	116.6	75%	0.753	66%	0.664	S	S	*	*			trans	-61.4	90.9	-178.6	0	0	0	0	0	112.3	K35 H39	K35-G37 PolarHBondContact O-N 3.21Å; G37-H39 PolarHBondContact O-N 3.07Å
38	E	36	Very low	48.1	Very low	171 Å²	171	112.9 Å²	112.9	80%	0.799	64%	0.642	S	S	*	*			trans	-63	124.2	156.1	-76.1	177.3	142.2	0	0	107.1	S36 E40	S36-E38 PolarHBondContact O-N 2.87Å; E38-E40 VanDerWaalsContact C-N 3.3Å; E38-E40 PolarHBondContact O-N 3.15Å
39	H	47.4	Very low	50.3	Low	140 Å²	140	116.9 Å²	116.9	65%	0.648	64%	0.639	S	S	*	*			trans	-64.7	88.6	176.7	-79.8	33.4	0	0	0	109.3	G37 I41	G37-H39 PolarHBondContact O-N 3.07Å; H39-I41 PolarHBondContact O-N 3.13Å
40	E	53.7	Low	52.5	Low	175 Å²	175	115.5 Å²	115.5	82%	0.818	62%	0.615	S	S	*	*			trans	-74.2	112.7	171.6	-83.1	-175.8	150.5	0	0	109.3	E38	E38-E40 VanDerWaalsContact C-N 3.3Å; E38-E40 PolarHBondContact O-N 3.15Å
41	I	60.8	Low	54.4	Low	114 Å²	114	109.9 Å²	109.9	59%	0.585	58%	0.578	S	S	*	*			trans	-54.7	124.6	163.9	-62.8	170.5	0	0	0	106.3	H39 D43 V180 A181	H39-I41 PolarHBondContact O-N 3.13Å; I41-D43 PolarHBondContact O-N 3.22Å; I41-V180 HydrophobicContact CG2-CB 4.16Å; I41-V180 HydrophobicContact CG2-CG2 3.88Å; I41-A181 HydrophobicContact CD1-CB 4.27Å; I41-A181 HydrophobicContact CG2-CB 4.48Å
42	P	62.8	Low	56.6	Low	29 Å²	29	104.2 Å²	104.2	19%	0.188	56%	0.564	C	S	.	*			trans	-57.2	129.6	-174.1	19	-29.3	0	0	0	109.9	L47 I50 V180	P42-L47 HydrophobicContact CB-CD1 4.09Å; P42-L47 HydrophobicContact CG-CD1 3.87Å; P42-L47 WeakPolarHBondContact O-CD1 3.2Å; P42-I50 HydrophobicContact CB-CD1 4.35Å; P42-V180 HydrophobicContact CG-CG1 4.09Å
43	D	71.3	Confident	59.2	Low	105 Å²	105	101.3 Å²	101.3	56%	0.561	53%	0.532	S	S	*	.			trans	-66.3	174.6	174.8	65.2	-3.4	0	0	0	110.9	I41 E45 G46 L47	I41-D43 PolarHBondContact O-N 3.22Å; D43-E45 PolarHBondContact O-N 2.9Å; D43-G46 PolarHBondContact O-N 3.31Å; D43-G46 VanDerWaalsContact O-N 3.11Å; D43-G46 WeakPolarHBondContact OD1-CA 3.42Å; D43-G46 PolarHBondContact OD1-N 3.03Å; D43-L47 PolarHBondContact O-N 2.78Å
44	R	68.4	Low	62	Low	170 Å²	170	96.9 Å²	96.9	64%	0.642	51%	0.513	S	S	*	.	H	α-helix	trans	-58.8	-36.6	-174.5	-71.3	-176.2	173.9	-173.5	-3.2	112.7	Q48 Q55	R44-Q48 PolarHBondContact O-N 2.94Å; R44-Q55 VanDerWaalsContact CZ-OE1 3.3Å
45	E	71.6	Confident	64.4	Low	126 Å²	126	94.3 Å²	94.3	59%	0.589	49%	0.49	S	S	*	.	H	α-helix	trans	-72.7	-38.4	177.6	-65.7	-168.9	179.1	0	0	111.7	D43 Q48 R49	D43-E45 PolarHBondContact O-N 2.9Å; E45-Q48 PolarHBondContact O-N 2.98Å; E45-R49 WeakPolarHBondContact O-CG 3.41Å; E45-R49 PolarHBondContact O-N 3.18Å
46	G	71.9	Confident	67	Low	17 Å²	17	87.9 Å²	87.9	18%	0.175	48%	0.477	C	S	.	.	H	α-helix	trans	-57.3	-45.8	170.8	0	0	0	0	0	112.3	D43 Q48 R49 I50	D43-G46 PolarHBondContact O-N 3.31Å; D43-G46 VanDerWaalsContact O-N 3.11Å; D43-G46 WeakPolarHBondContact OD1-CA 3.42Å; D43-G46 PolarHBondContact OD1-N 3.03Å; G46-Q48 PolarHBondContact O-N 3.45Å; G46-R49 PolarHBondContact O-N 3.08Å; G46-I50 WeakPolarHBondContact O-CD1 3.43Å; G46-I50 WeakPolarHBondContact O-CG1 3.36Å; G46-I50 PolarHBondContact O-N 3.03Å
47	L	72.8	Confident	69.6	Low	22 Å²	22	85.4 Å²	85.4	12%	0.115	45%	0.454	C	S	.	.	H	α-helix	trans	-62.6	-42	176	-107	97.1	0	0	0	113	P42 D43 R49 I50 T51 L178 V180	P42-L47 HydrophobicContact CB-CD1 4.09Å; P42-L47 HydrophobicContact CG-CD1 3.87Å; P42-L47 WeakPolarHBondContact O-CD1 3.2Å; D43-L47 PolarHBondContact O-N 2.78Å; L47-R49 VanDerWaalsContact C-N 3.32Å; L47-R49 PolarHBondContact O-N 2.79Å; L47-I50 PolarHBondContact O-N 2.99Å; L47-T51 WeakPolarHBondContact O-CB 3.48Å; L47-T51 WeakPolarHBondContact O-CG2 3.3Å; L47-T51 PolarHBondContact O-N 2.74Å; L47-T51 PolarHBondContact O-OG1 2.94Å; L47-L178 WeakPolarHBondContact CD2-O 3.25Å; L47-V180 HydrophobicContact CD1-CB 4.34Å; L47-V180 HydrophobicContact CD1-CG1 3.86Å; L47-V180 HydrophobicContact CD1-CG2 3.53Å; L47-V180 HydrophobicContact CD2-CG2 4.48Å
48	Q	78	Confident	72.3	Confident	101 Å²	101	82.1 Å²	82.1	47%	0.472	42%	0.42	S	S	.	.	H	α-helix	trans	-65.7	-36.4	178.8	179.8	167.9	-1.3	0	0	111.6	R44 E45 G46 G52 L53	R44-Q48 PolarHBondContact O-N 2.94Å; E45-Q48 PolarHBondContact O-N 2.98Å; G46-Q48 PolarHBondContact O-N 3.45Å; Q48-G52 WeakPolarHBondContact O-CA 3.41Å; Q48-G52 PolarHBondContact O-N 3.47Å; Q48-L53 WeakPolarHBondContact CG-O 3.49Å
49	R	73.5	Confident	75	Confident	207 Å²	207	76.8 Å²	76.8	78%	0.781	40%	0.399	S	S	*	.	H	α-helix	trans	-67	-37.3	173.5	-71.2	178.2	-169.2	-177.8	7.7	112.4	E45 G46 L47	E45-R49 WeakPolarHBondContact O-CG 3.41Å; E45-R49 PolarHBondContact O-N 3.18Å; G46-R49 PolarHBondContact O-N 3.08Å; L47-R49 VanDerWaalsContact C-N 3.32Å; L47-R49 PolarHBondContact O-N 2.79Å
50	I	74.6	Confident	77.2	Confident	36 Å²	36	74.5 Å²	74.5	19%	0.185	39%	0.391	C	S	.	.	H	α-helix	trans	-74.3	-46.2	-179.3	-68.2	165.2	0	0	0	111.5	P42 G46 L47 A245	P42-I50 HydrophobicContact CB-CD1 4.35Å; G46-I50 WeakPolarHBondContact O-CD1 3.43Å; G46-I50 WeakPolarHBondContact O-CG1 3.36Å; G46-I50 PolarHBondContact O-N 3.03Å; L47-I50 PolarHBondContact O-N 2.99Å; I50-A245 HydrophobicContact CG2-CB 3.41Å; I50-A245 VanDerWaalsContact CG2-CB 3.41Å
51	T	75.3	Confident	79.2	Confident	13 Å²	13	66.1 Å²	66.1	8%	0.08	35%	0.352	C	S	.	.	H	α-helix	trans	-88.6	-20.4	-174.4	59.7	0	0	0	0	113.2	L47 L53	L47-T51 WeakPolarHBondContact O-CB 3.48Å; L47-T51 WeakPolarHBondContact O-CG2 3.3Å; L47-T51 PolarHBondContact O-N 2.74Å; L47-T51 PolarHBondContact O-OG1 2.94Å; T51-L53 PolarHBondContact O-N 2.83Å; T51-L53 PolarHBondContact OG1-N 3.33Å
52	G	78.5	Confident	80.8	Confident	62 Å²	62	60.9 Å²	60.9	64%	0.639	33%	0.325	S	S	*	.	S	Bend	trans	72.3	7.8	-170.9	0	0	0	0	0	113.8	Q48	Q48-G52 WeakPolarHBondContact O-CA 3.41Å; Q48-G52 PolarHBondContact O-N 3.47Å
53	L	83.8	Confident	82.3	Confident	7 Å²	7	62.1 Å²	62.1	4%	0.037	34%	0.338	C	S	.	.			trans	-119.1	141	-169.5	-68.4	170.7	0	0	0	112.1	Q48 T51 H57 I61 L178 Q239	Q48-L53 WeakPolarHBondContact CG-O 3.49Å; T51-L53 PolarHBondContact O-N 2.83Å; T51-L53 PolarHBondContact OG1-N 3.33Å; L53-H57 HydrophobicContact CD2-CB 4.45Å; L53-I61 HydrophobicContact CD1-CD1 3.94Å; L53-L178 HydrophobicContact CD1-CD2 3.63Å; L53-Q239 HydrophobicContact CD2-CB 4.05Å; L53-Q239 HydrophobicContact CD2-CG 4.45Å
54	S	87.6	Confident	83.5	Confident	54 Å²	54	57.5 Å²	57.5	38%	0.378	31%	0.313	S	S	.	.			trans	-73	151.7	170.3	74.7	0	0	0	0	110.7	G56 H57 S58	S54-G56 PolarHBondContact O-N 3.24Å; S54-H57 WeakPolarHBondContact O-CB 3.44Å; S54-H57 PolarHBondContact O-N 3.05Å; S54-H57 WeakPolarHBondContact OG-CB 3.35Å; S54-H57 PolarHBondContact OG-N 2.88Å; S54-S58 PolarHBondContact O-N 2.86Å; S54-S58 PolarHBondContact O-OG 3.18Å
55	Q	83	Confident	84.8	Confident	69 Å²	69	49.4 Å²	49.4	32%	0.322	28%	0.283	S	S	.	.	H	α-helix	trans	-58.3	-34.3	178.1	-169.7	178.7	6.6	0	0	112.7	R44 T59	R44-Q55 VanDerWaalsContact CZ-OE1 3.3Å; Q55-T59 WeakPolarHBondContact O-CB 3.23Å; Q55-T59 PolarHBondContact O-N 2.72Å; Q55-T59 PolarHBondContact O-OG1 3.3Å
56	G	88.3	Confident	86	Confident	53 Å²	53	44.3 Å²	44.3	55%	0.546	26%	0.261	S	S	.	.	H	α-helix	trans	-63.7	-42.8	174.4	0	0	0	0	0	112	S54 T59 L60	S54-G56 PolarHBondContact O-N 3.24Å; G56-T59 PolarHBondContact O-N 2.83Å; G56-L60 WeakPolarHBondContact O-CB 3.42Å; G56-L60 PolarHBondContact O-N 3.38Å
57	H	89.9	Confident	87.1	Confident	49 Å²	49	46.7 Å²	46.7	23%	0.227	27%	0.265	C	S	.	.	H	α-helix	trans	-65.9	-46.4	175.5	-159.9	148	0	0	0	111.3	L53 S54 T59 L60 I61 V237	L53-H57 HydrophobicContact CD2-CB 4.45Å; S54-H57 WeakPolarHBondContact O-CB 3.44Å; S54-H57 PolarHBondContact O-N 3.05Å; S54-H57 WeakPolarHBondContact OG-CB 3.35Å; S54-H57 PolarHBondContact OG-N 2.88Å; H57-T59 VanDerWaalsContact C-N 3.26Å; H57-T59 PolarHBondContact O-N 2.67Å; H57-L60 CarbonylContact O-C 3.58Å; H57-L60 WeakPolarHBondContact O-CA 3.4Å; H57-L60 WeakPolarHBondContact O-CB 3.49Å; H57-L60 PolarHBondContact O-N 3.03Å; H57-I61 WeakPolarHBondContact O-CG1 3.35Å; H57-I61 PolarHBondContact O-N 2.92Å; H57-V237 PolarHBondContact NE2-O 3.14Å
58	S	90.1	Very high	88.2	Confident	5 Å²	5	45.6 Å²	45.6	4%	0.035	26%	0.26	C	S	.	.	H	α-helix	trans	-58.9	-38.4	176.5	-57.1	0	0	0	0	112.3	S54 I61 V62	S54-S58 PolarHBondContact O-N 2.86Å; S54-S58 PolarHBondContact O-OG 3.18Å; S58-I61 PolarHBondContact O-N 3.43Å; S58-V62 WeakPolarHBondContact O-CG2 3.42Å; S58-V62 PolarHBondContact O-N 3.34Å; S58-V62 VanDerWaalsContact O-N 3.11Å
59	T	91.7	Very high	89	Confident	59 Å²	59	40.9 Å²	40.9	36%	0.362	24%	0.238	S	C	.	.	H	α-helix	trans	-67.8	-39.5	175.1	-53.5	0	0	0	0	111.6	Q55 G56 H57 I61 V62 A63	Q55-T59 WeakPolarHBondContact O-CB 3.23Å; Q55-T59 PolarHBondContact O-N 2.72Å; Q55-T59 PolarHBondContact O-OG1 3.3Å; G56-T59 PolarHBondContact O-N 2.83Å; H57-T59 VanDerWaalsContact C-N 3.26Å; H57-T59 PolarHBondContact O-N 2.67Å; T59-I61 VanDerWaalsContact C-N 3.33Å; T59-I61 PolarHBondContact O-N 3.13Å; T59-V62 PolarHBondContact O-N 2.8Å; T59-A63 PolarHBondContact O-N 2.71Å
60	L	94.7	Very high	90.1	Very high	91 Å²	91	33.1 Å²	33.1	48%	0.476	21%	0.211	S	C	.	.	H	α-helix	trans	-63.4	-38.4	174.4	-176.9	66.5	0	0	0	111.8	G56 H57 A63 V64 V237	G56-L60 WeakPolarHBondContact O-CB 3.42Å; G56-L60 PolarHBondContact O-N 3.38Å; H57-L60 CarbonylContact O-C 3.58Å; H57-L60 WeakPolarHBondContact O-CA 3.4Å; H57-L60 WeakPolarHBondContact O-CB 3.49Å; H57-L60 PolarHBondContact O-N 3.03Å; L60-A63 WeakPolarHBondContact O-CB 3.3Å; L60-A63 PolarHBondContact O-N 3.35Å; L60-V64 WeakPolarHBondContact O-CG2 3.39Å; L60-V64 PolarHBondContact O-N 3.49Å; L60-V237 HydrophobicContact CD2-CG1 3.59Å; L60-V237 HydrophobicContact CG-CG1 3.67Å
61	I	94.6	Very high	91	Very high	0 Å²	0	32 Å²	32	0%	0	21%	0.206	C	C	.	.	H	α-helix	trans	-59.3	-48.5	172.8	-69.8	167.2	0	0	0	110.1	L53 H57 S58 T59 A63 V64 L65 L174 L178 V238	L53-I61 HydrophobicContact CD1-CD1 3.94Å; H57-I61 WeakPolarHBondContact O-CG1 3.35Å; H57-I61 PolarHBondContact O-N 2.92Å; S58-I61 PolarHBondContact O-N 3.43Å; T59-I61 VanDerWaalsContact C-N 3.33Å; T59-I61 PolarHBondContact O-N 3.13Å; I61-A63 VanDerWaalsContact C-N 3.29Å; I61-A63 PolarHBondContact O-N 2.71Å; I61-V64 PolarHBondContact O-N 3.42Å; I61-V64 VanDerWaalsContact O-N 3.16Å; I61-L65 HydrophobicContact CG2-CD1 4.01Å; I61-L65 HydrophobicContact CG2-CG 4.33Å; I61-L65 WeakPolarHBondContact O-CG 3.47Å; I61-L65 PolarHBondContact O-N 3.04Å; I61-L174 HydrophobicContact CG2-CD2 4.37Å; I61-L178 HydrophobicContact CB-CD1 4.09Å; I61-L178 HydrophobicContact CD1-CD1 4.32Å; I61-L178 HydrophobicContact CD1-CD2 4.41Å; I61-L178 HydrophobicContact CG2-CD1 3.6Å; I61-V238 HydrophobicContact CG1-CG2 4.42Å; I61-V238 HydrophobicContact CG2-CG1 4.18Å; I61-V238 HydrophobicContact CG2-CG2 4.11Å
62	V	94.1	Very high	91.9	Very high	4 Å²	4	31.4 Å²	31.4	2%	0.024	20%	0.202	C	C	.	.	H	α-helix	trans	-59	-41.7	176.1	175.6	0	0	0	0	111	S58 T59 V64 L65 C66 I175 F179 M187	S58-V62 WeakPolarHBondContact O-CG2 3.42Å; S58-V62 PolarHBondContact O-N 3.34Å; S58-V62 VanDerWaalsContact O-N 3.11Å; T59-V62 PolarHBondContact O-N 2.8Å; V62-V64 VanDerWaalsContact C-N 3.33Å; V62-V64 PolarHBondContact O-N 3.37Å; V62-L65 CarbonylContact O-C 3.59Å; V62-L65 PolarHBondContact O-N 3.3Å; V62-C66 WeakPolarHBondContact O-CB 3.3Å; V62-C66 PolarHBondContact O-N 3.2Å; V62-C66 PolarHBondContact O-SG 3.21Å; V62-I175 HydrophobicContact CG2-CG1 4.34Å; V62-I175 HydrophobicContact CG2-CG2 4.4Å; V62-F179 HydrophobicContact CG2-CD2 4.39Å; V62-F179 HydrophobicContact CG2-CE2 3.4Å; V62-F179 HydrophobicContact CG2-CZ 3.94Å; V62-M187 HydrophobicContact CB-SD 4.49Å; V62-M187 HydrophobicContact CG1-CB 4.35Å; V62-M187 HydrophobicContact CG1-SD 4.09Å; V62-M187 HydrophobicContact CG2-CB 4.26Å; V62-M187 HydrophobicContact CG2-CG 4.35Å; V62-M187 HydrophobicContact CG2-SD 4.38Å
63	A	95.4	Very high	92.6	Very high	54 Å²	54	30.2 Å²	30.2	45%	0.446	18%	0.179	S	C	.	.	H	α-helix	trans	-60.5	-41.4	177	0	0	0	0	0	112.5	T59 L60 I61 C66 Y67	T59-A63 PolarHBondContact O-N 2.71Å; L60-A63 WeakPolarHBondContact O-CB 3.3Å; L60-A63 PolarHBondContact O-N 3.35Å; I61-A63 VanDerWaalsContact C-N 3.29Å; I61-A63 PolarHBondContact O-N 2.71Å; A63-C66 PolarHBondContact O-N 2.86Å; A63-Y67 WeakPolarHBondContact O-CB 3.23Å; A63-Y67 PolarHBondContact O-N 3.21Å
64	V	96.2	Very high	93.1	Very high	8 Å²	8	30.5 Å²	30.5	5%	0.048	18%	0.18	C	C	.	.	H	α-helix	trans	-63.9	-43.6	174.3	172.2	0	0	0	0	111.1	L60 I61 V62 Y67 I68 L233 L234 V237 V238	L60-V64 WeakPolarHBondContact O-CG2 3.39Å; L60-V64 PolarHBondContact O-N 3.49Å; I61-V64 PolarHBondContact O-N 3.42Å; I61-V64 VanDerWaalsContact O-N 3.16Å; V62-V64 VanDerWaalsContact C-N 3.33Å; V62-V64 PolarHBondContact O-N 3.37Å; V64-Y67 WeakPolarHBondContact O-CB 3.37Å; V64-Y67 PolarHBondContact O-N 3.04Å; V64-I68 HydrophobicContact CG1-CD1 3.83Å; V64-I68 WeakPolarHBondContact O-CD1 3.43Å; V64-I68 VanDerWaalsContact O-CG1 3.29Å; V64-I68 WeakPolarHBondContact O-CG1 3.41Å; V64-I68 PolarHBondContact O-N 2.67Å; V64-L233 HydrophobicContact CG1-CB 3.98Å; V64-L233 HydrophobicContact CG2-CB 4.28Å; V64-L234 HydrophobicContact CG1-CB 4.49Å; V64-V237 HydrophobicContact CG2-CB 4.2Å; V64-V237 HydrophobicContact CG2-CG1 4.05Å; V64-V237 HydrophobicContact CG2-CG2 4.42Å; V64-V238 HydrophobicContact CG1-CG2 4.25Å
65	L	95.9	Very high	93.3	Very high	0 Å²	0	28.2 Å²	28.2	0%	0	16%	0.163	C	C	.	.	H	α-helix	trans	-64.5	-41	175.1	-61.8	175.1	0	0	0	111.4	I61 V62 Y67 I68 N69 M128 Y167 A171 L174 I175 F191 L234	I61-L65 HydrophobicContact CG2-CD1 4.01Å; I61-L65 HydrophobicContact CG2-CG 4.33Å; I61-L65 WeakPolarHBondContact O-CG 3.47Å; I61-L65 PolarHBondContact O-N 3.04Å; V62-L65 CarbonylContact O-C 3.59Å; V62-L65 PolarHBondContact O-N 3.3Å; L65-Y67 VanDerWaalsContact C-N 3.32Å; L65-Y67 PolarHBondContact O-N 3.02Å; L65-I68 PolarHBondContact O-N 3.34Å; L65-N69 WeakPolarHBondContact O-CB 3.49Å; L65-N69 PolarHBondContact O-N 2.96Å; L65-M128 HydrophobicContact CD2-CE 4.4Å; L65-M128 HydrophobicContact CD2-SD 4.27Å; L65-Y167 VanDerWaalsContact CA-OH 3.25Å; L65-Y167 WeakPolarHBondContact CA-OH 3.37Å; L65-Y167 HydrophobicContact CD2-CE2 4.03Å; L65-Y167 PolarHBondContact O-OH 2.78Å; L65-A171 HydrophobicContact CD2-CB 4.22Å; L65-L174 HydrophobicContact CD1-CD2 4Å; L65-L174 HydrophobicContact CD1-CG 4.47Å; L65-L174 HydrophobicContact CD2-CD2 4.36Å; L65-I175 HydrophobicContact CD1-CD1 4.07Å; L65-I175 HydrophobicContact CD1-CG1 3.59Å; L65-F191 HydrophobicContact CB-CD2 4.28Å; L65-F191 HydrophobicContact CB-CE2 4.28Å; L65-L234 HydrophobicContact CD2-CD1 4.33Å
66	C	95.5	Very high	93.8	Very high	20 Å²	20	25.3 Å²	25.3	14%	0.135	15%	0.149	C	C	.	.	H	α-helix	trans	-62.2	-40.6	175.2	-68.5	0	0	0	0	111.8	V62 A63 N69 L70 F191	V62-C66 WeakPolarHBondContact O-CB 3.3Å; V62-C66 PolarHBondContact O-N 3.2Å; V62-C66 PolarHBondContact O-SG 3.21Å; A63-C66 PolarHBondContact O-N 2.86Å; C66-N69 PolarHBondContact O-N 3.38Å; C66-L70 WeakPolarHBondContact O-CB 3.36Å; C66-L70 PolarHBondContact O-N 2.79Å; C66-F191 VanDerWaalsContact SG-CA 3.6Å
67	Y	95.9	Very high	94	Very high	66 Å²	66	24 Å²	24	26%	0.259	13%	0.128	S	C	.	.	H	α-helix	trans	-60.8	-47.3	174.1	170.4	-107.2	0	0	0	112	A63 V64 L65 N69 L70 L71 L226 A230 L233	A63-Y67 WeakPolarHBondContact O-CB 3.23Å; A63-Y67 PolarHBondContact O-N 3.21Å; V64-Y67 WeakPolarHBondContact O-CB 3.37Å; V64-Y67 PolarHBondContact O-N 3.04Å; L65-Y67 VanDerWaalsContact C-N 3.32Å; L65-Y67 PolarHBondContact O-N 3.02Å; Y67-N69 VanDerWaalsContact C-N 3.32Å; Y67-N69 PolarHBondContact O-N 3.09Å; Y67-L70 WeakPolarHBondContact O-CB 3.44Å; Y67-L70 PolarHBondContact O-N 3.21Å; Y67-L71 HydrophobicContact CD1-CD1 4.24Å; Y67-L71 HydrophobicContact CE1-CD1 3.57Å; Y67-L71 HydrophobicContact CE1-CG 4.32Å; Y67-L71 HydrophobicContact CE2-CD1 4.21Å; Y67-L71 HydrophobicContact CE2-CD2 4.35Å; Y67-L71 HydrophobicContact CE2-CG 4.18Å; Y67-L71 WeakPolarHBondContact O-CG 3.47Å; Y67-L71 PolarHBondContact O-N 3.35Å; Y67-L226 PolarHBondContact OH-O 2.96Å; Y67-A230 HydrophobicContact CD1-CB 4.29Å; Y67-A230 HydrophobicContact CE1-CB 3.8Å; Y67-L233 HydrophobicContact CD1-CD1 4.23Å; Y67-L233 HydrophobicContact CE1-CD1 4.22Å
68	I	96.1	Very high	94.2	Very high	0 Å²	0	21.6 Å²	21.6	0%	0	12%	0.118	C	C	.	.	H	α-helix	trans	-65.2	-38.5	177.7	-61.3	156	0	0	0	110.8	V64 L65 L70 L71 N72 I132 W135 Y167 A230 L234	V64-I68 HydrophobicContact CG1-CD1 3.83Å; V64-I68 WeakPolarHBondContact O-CD1 3.43Å; V64-I68 VanDerWaalsContact O-CG1 3.29Å; V64-I68 WeakPolarHBondContact O-CG1 3.41Å; V64-I68 PolarHBondContact O-N 2.67Å; L65-I68 PolarHBondContact O-N 3.34Å; I68-L70 VanDerWaalsContact C-N 3.34Å; I68-L71 PolarHBondContact O-N 2.94Å; I68-N72 WeakPolarHBondContact O-CB 3.33Å; I68-N72 PolarHBondContact O-N 2.79Å; I68-I132 HydrophobicContact CD1-CD1 4.15Å; I68-I132 HydrophobicContact CG2-CD1 4.08Å; I68-I132 HydrophobicContact CG2-CG1 4.23Å; I68-W135 HydrophobicContact CG2-CH2 4.17Å; I68-W135 HydrophobicContact CG2-CZ2 4.34Å; I68-Y167 HydrophobicContact CB-CE1 4.26Å; I68-Y167 HydrophobicContact CB-CE2 3.79Å; I68-Y167 HydrophobicContact CD1-CE2 4.14Å; I68-Y167 HydrophobicContact CG2-CD1 4.05Å; I68-Y167 HydrophobicContact CG2-CD2 3.65Å; I68-Y167 HydrophobicContact CG2-CE1 3.78Å; I68-Y167 HydrophobicContact CG2-CE2 3.36Å; I68-Y167 HydrophobicContact CG2-CG 3.99Å; I68-Y167 VanDerWaalsContact CG2-CZ 3.43Å; I68-A230 HydrophobicContact CG1-CB 3.79Å; I68-L234 HydrophobicContact CD1-CB 4.07Å; I68-L234 HydrophobicContact CD1-CD1 3.43Å; I68-L234 VanDerWaalsContact CD1-CD1 3.43Å; I68-L234 HydrophobicContact CD1-CG 4.32Å
69	N	95.4	Very high	94.3	Very high	2 Å²	2	21.6 Å²	21.6	1%	0.011	12%	0.117	C	C	.	.	H	α-helix	trans	-65.1	-39.7	176.7	-161.8	39.9	0	0	0	111.4	L65 C66 Y67 N72 Y73 Y167 F191 A194	L65-N69 WeakPolarHBondContact O-CB 3.49Å; L65-N69 PolarHBondContact O-N 2.96Å; C66-N69 PolarHBondContact O-N 3.38Å; Y67-N69 VanDerWaalsContact C-N 3.32Å; Y67-N69 PolarHBondContact O-N 3.09Å; N69-N72 WeakPolarHBondContact O-CB 3.5Å; N69-N72 PolarHBondContact O-N 3.37Å; N69-Y73 WeakPolarHBondContact O-CD2 3.34Å; N69-Y73 PolarHBondContact O-N 2.95Å; N69-Y73 VanDerWaalsContact O-N 3.13Å; N69-Y167 HydrophobicContact CB-CE1 4Å; N69-F191 HydrophobicContact CB-CD2 4.11Å; N69-F191 HydrophobicContact CB-CE2 3.62Å; N69-F191 HydrophobicContact CB-CZ 3.94Å; N69-F191 PolarHBondContact ND2-O 3.13Å; N69-A194 HydrophobicContact CB-CB 4.24Å
70	L	94.6	Very high	94.4	Very high	43 Å²	43	18.8 Å²	18.8	23%	0.225	10%	0.1	C	C	.	.	H	α-helix	trans	-60.4	-46.5	172.7	-174.3	156.4	0	0	0	110.8	C66 Y67 I68 N72 Y73 M74 A194 V197 L201	C66-L70 WeakPolarHBondContact O-CB 3.36Å; C66-L70 PolarHBondContact O-N 2.79Å; Y67-L70 WeakPolarHBondContact O-CB 3.44Å; Y67-L70 PolarHBondContact O-N 3.21Å; I68-L70 VanDerWaalsContact C-N 3.34Å; L70-N72 VanDerWaalsContact C-N 3.34Å; L70-N72 PolarHBondContact O-N 2.92Å; L70-Y73 PolarHBondContact O-N 3.3Å; L70-M74 HydrophobicContact CD2-SD 4.48Å; L70-M74 VanDerWaalsContact O-CB 3.3Å; L70-M74 WeakPolarHBondContact O-CB 3.5Å; L70-M74 PolarHBondContact O-N 3.29Å; L70-A194 HydrophobicContact CB-CB 4.3Å; L70-V197 HydrophobicContact CD1-CG1 4.33Å; L70-L201 HydrophobicContact CD1-CD1 3.99Å; L70-L201 HydrophobicContact CD2-CD1 3.84Å; L70-L201 HydrophobicContact CG-CD1 4.17Å
71	L	93.9	Very high	94.2	Very high	13 Å²	13	14.5 Å²	14.5	7%	0.068	8%	0.078	C	C	.	.	H	α-helix	trans	-61.7	-39.6	176.1	-70.7	-177.4	0	0	0	112.9	Y67 I68 M74 D75 L226 A230	Y67-L71 HydrophobicContact CD1-CD1 4.24Å; Y67-L71 HydrophobicContact CE1-CD1 3.57Å; Y67-L71 HydrophobicContact CE1-CG 4.32Å; Y67-L71 HydrophobicContact CE2-CD1 4.21Å; Y67-L71 HydrophobicContact CE2-CD2 4.35Å; Y67-L71 HydrophobicContact CE2-CG 4.18Å; Y67-L71 WeakPolarHBondContact O-CG 3.47Å; Y67-L71 PolarHBondContact O-N 3.35Å; I68-L71 PolarHBondContact O-N 2.94Å; L71-M74 HydrophobicContact CD2-CE 3.55Å; L71-M74 WeakPolarHBondContact O-CB 3.38Å; L71-M74 PolarHBondContact O-N 2.94Å; L71-D75 PolarHBondContact O-N 2.87Å; L71-L226 HydrophobicContact CD1-CB 3.93Å; L71-L226 HydrophobicContact CD2-CB 3.62Å; L71-L226 HydrophobicContact CD2-CD1 3.74Å; L71-L226 HydrophobicContact CD2-CG 4.3Å; L71-L226 HydrophobicContact CG-CB 4.45Å; L71-A230 HydrophobicContact CD1-CB 3.74Å
72	N	94.8	Very high	94.2	Very high	0 Å²	0	14.5 Å²	14.5	0%	0	8%	0.078	C	C	.	.	H	α-helix	trans	-57.2	-52.6	177.2	177.3	-92	0	0	0	110.9	I68 N69 L70 M74 D75 R76 E164	I68-N72 WeakPolarHBondContact O-CB 3.33Å; I68-N72 PolarHBondContact O-N 2.79Å; N69-N72 WeakPolarHBondContact O-CB 3.5Å; N69-N72 PolarHBondContact O-N 3.37Å; L70-N72 VanDerWaalsContact C-N 3.34Å; L70-N72 PolarHBondContact O-N 2.92Å; N72-M74 VanDerWaalsContact C-N 3.31Å; N72-M74 PolarHBondContact O-N 3.42Å; N72-D75 PolarHBondContact O-N 3.47Å; N72-R76 PolarHBondContact O-N 3.09Å; N72-R76 VanDerWaalsContact O-N 3.15Å; N72-E164 WeakPolarHBondContact ND2-CB 3.23Å; N72-E164 WeakPolarHBondContact ND2-CG 3.36Å; N72-E164 PolarHBondContact ND2-OE2 2.94Å; N72-E164 PolarHBondContact OD1-OE2 3.43Å
73	Y	93.2	Very high	94.2	Very high	38 Å²	38	14.3 Å²	14.3	15%	0.149	8%	0.076	C	C	.	.	H	α-helix	trans	-69.9	-29.3	177.7	-80.5	-88.5	0	0	0	113	N69 L70 F77 I195	N69-Y73 WeakPolarHBondContact O-CD2 3.34Å; N69-Y73 PolarHBondContact O-N 2.95Å; N69-Y73 VanDerWaalsContact O-N 3.13Å; L70-Y73 PolarHBondContact O-N 3.3Å; Y73-F77 HydrophobicContact CD1-CE2 4.17Å; Y73-F77 VanDerWaalsContact O-CD2 3.3Å; Y73-F77 WeakPolarHBondContact O-CD2 3.49Å; Y73-F77 PolarHBondContact O-N 3.17Å; Y73-I195 HydrophobicContact CD1-CB 4.43Å; Y73-I195 HydrophobicContact CD1-CG2 3.79Å; Y73-I195 HydrophobicContact CD2-CB 4.41Å; Y73-I195 HydrophobicContact CD2-CG1 3.99Å; Y73-I195 HydrophobicContact CE1-CB 4.23Å; Y73-I195 HydrophobicContact CE1-CG1 4.2Å; Y73-I195 HydrophobicContact CE1-CG2 3.44Å; Y73-I195 VanDerWaalsContact CE1-CG2 3.44Å; Y73-I195 HydrophobicContact CE2-CB 4.24Å; Y73-I195 HydrophobicContact CE2-CD1 4.06Å; Y73-I195 HydrophobicContact CE2-CG1 3.49Å; Y73-I195 VanDerWaalsContact CE2-CG1 3.49Å; Y73-I195 HydrophobicContact CE2-CG2 4.32Å; Y73-I195 HydrophobicContact CG-CG2 4.33Å; Y73-I195 WeakPolarHBondContact OH-CD1 3.37Å
74	M	94.1	Very high	94	Very high	13 Å²	13	12.4 Å²	12.4	6%	0.064	6%	0.06	C	C	.	.	H	α-helix	trans	-63.6	-47.3	172.9	-164	171.8	76.8	0	0	111.3	L70 L71 N72 R76 F77 T78 G198 L201 G202 A205 T223 L226	L70-M74 HydrophobicContact CD2-SD 4.48Å; L70-M74 VanDerWaalsContact O-CB 3.3Å; L70-M74 WeakPolarHBondContact O-CB 3.5Å; L70-M74 PolarHBondContact O-N 3.29Å; L71-M74 HydrophobicContact CD2-CE 3.55Å; L71-M74 WeakPolarHBondContact O-CB 3.38Å; L71-M74 PolarHBondContact O-N 2.94Å; N72-M74 VanDerWaalsContact C-N 3.31Å; N72-M74 PolarHBondContact O-N 3.42Å; M74-R76 VanDerWaalsContact C-N 3.32Å; M74-R76 PolarHBondContact O-N 2.91Å; M74-F77 PolarHBondContact O-N 3.49Å; M74-T78 WeakPolarHBondContact O-CB 3.38Å; M74-T78 PolarHBondContact O-N 3.43Å; M74-T78 PolarHBondContact O-OG1 3.28Å; M74-G198 VanDerWaalsContact CA-O 3.29Å; M74-G198 WeakPolarHBondContact CA-O 3.19Å; M74-G198 PolarHBondContact N-O 3Å; M74-L201 HydrophobicContact CG-CB 4.31Å; M74-L201 HydrophobicContact SD-CB 4.17Å; M74-G202 VanDerWaalsContact O-CA 3.29Å; M74-G202 WeakPolarHBondContact O-CA 3.45Å; M74-A205 HydrophobicContact CG-CB 4.33Å; M74-A205 HydrophobicContact SD-CB 4.21Å; M74-T223 HydrophobicContact CE-CG2 3.89Å; M74-L226 HydrophobicContact CE-CD1 3.5Å; M74-L226 VanDerWaalsContact CE-CD1 3.5Å
75	D	92.8	Very high	93.8	Very high	5 Å²	5	12.2 Å²	12.2	3%	0.027	6%	0.058	C	C	.	.	H	α-helix	trans	-60.6	-42.7	177.9	-159.9	67.4	0	0	0	111.7	L71 N72 F77 T78 T139 R157 T223	L71-D75 PolarHBondContact O-N 2.87Å; N72-D75 PolarHBondContact O-N 3.47Å; D75-F77 VanDerWaalsContact C-N 3.26Å; D75-F77 PolarHBondContact O-N 3.25Å; D75-T78 PolarHBondContact O-N 3.01Å; D75-T139 WeakPolarHBondContact OD1-CG2 3.35Å; D75-T139 PolarHBondContact OD2-OG1 3.43Å; D75-R157 IonicContact OD2-NH1 3.2Å; D75-T223 WeakPolarHBondContact OD1-CB 3.3Å; D75-T223 PolarHBondContact OD1-OG1 3.22Å
76	R	92.5	Very high	93.7	Very high	8 Å²	8	12.2 Å²	12.2	3%	0.03	6%	0.059	C	C	.	.	H	α-helix	trans	-54.6	-39.1	178.9	-166.3	174.5	-163.2	156.8	5.4	113.5	N72 M74 F104	N72-R76 PolarHBondContact O-N 3.09Å; N72-R76 VanDerWaalsContact O-N 3.15Å; M74-R76 VanDerWaalsContact C-N 3.32Å; M74-R76 PolarHBondContact O-N 2.91Å; R76-F104 HydrophobicContact CB-CZ 4.5Å; R76-F104 HydrophobicContact CG-CD1 4.49Å; R76-F104 HydrophobicContact CG-CE1 3.71Å; R76-F104 HydrophobicContact CG-CZ 4Å
77	F	93.4	Very high	93.6	Very high	25 Å²	25	12.3 Å²	12.3	11%	0.11	6%	0.057	C	C	.	.	H	α-helix	trans	-106.4	-4.9	-175.6	-65	-67.1	0	0	0	114.5	Y73 M74 D75 V79 A80 G81 S199 Y203 A291	Y73-F77 HydrophobicContact CD1-CE2 4.17Å; Y73-F77 VanDerWaalsContact O-CD2 3.3Å; Y73-F77 WeakPolarHBondContact O-CD2 3.49Å; Y73-F77 PolarHBondContact O-N 3.17Å; M74-F77 PolarHBondContact O-N 3.49Å; D75-F77 VanDerWaalsContact C-N 3.26Å; D75-F77 PolarHBondContact O-N 3.25Å; F77-V79 VanDerWaalsContact C-N 3.26Å; F77-V79 PolarHBondContact O-N 2.96Å; F77-A80 PolarHBondContact O-N 2.85Å; F77-A80 VanDerWaalsContact O-N 3.17Å; F77-G81 PolarHBondContact O-N 3.47Å; F77-S199 VanDerWaalsContact CD2-CB 3.45Å; F77-S199 WeakPolarHBondContact CD2-OG 3.32Å; F77-S199 WeakPolarHBondContact CE2-OG 3.21Å; F77-Y203 HydrophobicContact CB-CD1 4.39Å; F77-Y203 HydrophobicContact CB-CD2 4.44Å; F77-Y203 HydrophobicContact CB-CE1 4.08Å; F77-Y203 HydrophobicContact CB-CE2 4.14Å; F77-Y203 HydrophobicContact CD1-CE1 4.19Å; F77-Y203 HydrophobicContact CD1-CE2 4.39Å; F77-Y203 AromaticContact CD1-CZ 3.69Å; F77-Y203 WeakPolarHBondContact CD1-OH 3.45Å; F77-Y203 HydrophobicContact CG-CE1 4.48Å; F77-Y203 HydrophobicContact CG-CE2 4.25Å; F77-Y203 AromaticContact CG-CZ 3.95Å; F77-A291 HydrophobicContact CD1-CB 4.2Å; F77-A291 HydrophobicContact CE1-CB 3.53Å; F77-A291 HydrophobicContact CZ-CB 4.28Å
78	T	93.4	Very high	93.4	Very high	0 Å²	0	11 Å²	11	0%	0	5%	0.053	C	C	.	.	H	α-helix	trans	-58.2	-41.4	172.8	-65.7	0	0	0	0	111.3	M74 D75 A80 G81 V82 G202 A219 L220	M74-T78 WeakPolarHBondContact O-CB 3.38Å; M74-T78 PolarHBondContact O-N 3.43Å; M74-T78 PolarHBondContact O-OG1 3.28Å; D75-T78 PolarHBondContact O-N 3.01Å; T78-A80 PolarHBondContact O-N 3.24Å; T78-G81 PolarHBondContact O-N 3.37Å; T78-V82 PolarHBondContact O-N 3.23Å; T78-G202 WeakPolarHBondContact CA-O 3.3Å; T78-A219 HydrophobicContact CG2-CB 3.9Å; T78-A219 WeakPolarHBondContact CG2-O 3.37Å; T78-L220 HydrophobicContact CG2-CD2 4.24Å
79	V	93.1	Very high	93.2	Very high	4 Å²	4	13.7 Å²	13.7	2%	0.024	7%	0.065	C	C	.	.	H	α-helix	trans	-61.2	-42.2	176.6	176.2	0	0	0	0	111.7	F77 G81 V82 L83 I86 I100 L220	F77-V79 VanDerWaalsContact C-N 3.26Å; F77-V79 PolarHBondContact O-N 2.96Å; V79-G81 VanDerWaalsContact C-N 3.29Å; V79-G81 PolarHBondContact O-N 3.23Å; V79-V82 CarbonylContact O-C 3.58Å; V79-V82 PolarHBondContact O-N 3.42Å; V79-L83 PolarHBondContact O-N 2.94Å; V79-I86 HydrophobicContact CG1-CD1 3.78Å; V79-I100 HydrophobicContact CG1-CG2 3.8Å; V79-L220 HydrophobicContact CG2-CD2 3.91Å
80	A	91.9	Very high	93.1	Very high	1 Å²	1	14.3 Å²	14.3	1%	0.008	7%	0.068	C	C	.	.	H	α-helix	trans	-66.4	-33	177.4	0	0	0	0	0	112	F77 T78 V82 L83 Y203 L292	F77-A80 PolarHBondContact O-N 2.85Å; F77-A80 VanDerWaalsContact O-N 3.17Å; T78-A80 PolarHBondContact O-N 3.24Å; A80-V82 PolarHBondContact O-N 2.83Å; A80-L83 WeakPolarHBondContact O-CB 3.22Å; A80-L83 PolarHBondContact O-N 3Å; A80-Y203 HydrophobicContact CB-CD1 4.1Å; A80-Y203 HydrophobicContact CB-CE1 3.55Å; A80-L292 HydrophobicContact CB-CD1 4.18Å
81	G	91.6	Very high	93	Very high	0 Å²	0	15.9 Å²	15.9	0%	0	8%	0.082	C	C	.	.	H	α-helix	trans	-63	-25.4	175	0	0	0	0	0	114.7	F77 T78 V79 S322	F77-G81 PolarHBondContact O-N 3.47Å; T78-G81 PolarHBondContact O-N 3.37Å; V79-G81 VanDerWaalsContact C-N 3.29Å; V79-G81 PolarHBondContact O-N 3.23Å; G81-S322 PolarHBondContact O-OG 3.13Å
82	V	93.4	Very high	93	Very high	0 Å²	0	16.7 Å²	16.7	0%	0	9%	0.086	C	C	.	.	T	Hydrogen-bonded Turn	trans	-118.1	17.2	178.7	-58.9	0	0	0	0	113.2	T78 V79 A80 P84 D85 I86 G206 K210 W216 A219	T78-V82 PolarHBondContact O-N 3.23Å; V79-V82 CarbonylContact O-C 3.58Å; V79-V82 PolarHBondContact O-N 3.42Å; A80-V82 PolarHBondContact O-N 2.83Å; V82-P84 VanDerWaalsContact C-CD 3.45Å; V82-D85 WeakPolarHBondContact O-CB 3.47Å; V82-D85 PolarHBondContact O-N 3.42Å; V82-D85 VanDerWaalsContact O-N 3.13Å; V82-I86 HydrophobicContact CG2-CD1 3.95Å; V82-I86 HydrophobicContact CG2-CG1 4.35Å; V82-I86 PolarHBondContact O-N 3.18Å; V82-G206 WeakPolarHBondContact CG1-O 3.38Å; V82-K210 HydrophobicContact CG1-CB 4.09Å; V82-K210 HydrophobicContact CG1-CD 4.05Å; V82-W216 HydrophobicContact CB-CB 4.22Å; V82-W216 HydrophobicContact CG1-CB 4.45Å; V82-W216 HydrophobicContact CG2-CE3 4.31Å; V82-A219 HydrophobicContact CG1-CB 3.74Å; V82-A219 HydrophobicContact CG2-CB 4.35Å
83	L	94	Very high	92.9	Very high	0 Å²	0	17.5 Å²	17.5	0%	0	10%	0.095	C	C	.	.	H	α-helix	trans	-55.3	-42.7	-175.3	-174.1	66.1	0	0	0	113.9	V79 A80 D85 I86 E87 I100 L292 W293 A296	V79-L83 PolarHBondContact O-N 2.94Å; A80-L83 WeakPolarHBondContact O-CB 3.22Å; A80-L83 PolarHBondContact O-N 3Å; L83-D85 VanDerWaalsContact C-N 3.28Å; L83-D85 PolarHBondContact O-N 3.3Å; L83-I86 WeakPolarHBondContact O-CB 3.23Å; L83-I86 PolarHBondContact O-N 2.94Å; L83-I86 VanDerWaalsContact O-N 3.12Å; L83-E87 HydrophobicContact CG-CG 4.37Å; L83-E87 WeakPolarHBondContact O-CG 3.41Å; L83-E87 PolarHBondContact O-N 3.09Å; L83-I100 HydrophobicContact CD1-CD1 4.42Å; L83-L292 HydrophobicContact CD1-CD1 4.29Å; L83-L292 HydrophobicContact CD2-CD1 3.77Å; L83-L292 HydrophobicContact CD2-CG 3.81Å; L83-W293 HydrophobicContact CD2-CZ3 4.46Å; L83-A296 HydrophobicContact CD2-CB 4.34Å
84	P	92.5	Very high	93	Very high	15 Å²	15	15.8 Å²	15.8	10%	0.097	9%	0.088	C	C	.	.	H	α-helix	trans	-59.5	-36.3	178.8	-25.5	36.7	0	0	0	113.6	V82 E87 Q88 A296 L299 C317	V82-P84 VanDerWaalsContact C-CD 3.45Å; P84-E87 PolarHBondContact O-N 3.47Å; P84-Q88 WeakPolarHBondContact O-CB 3.41Å; P84-Q88 PolarHBondContact O-N 3.22Å; P84-Q88 VanDerWaalsContact O-N 3.12Å; P84-A296 HydrophobicContact CG-CB 4.44Å; P84-L299 HydrophobicContact CB-CD2 3.55Å; P84-L299 HydrophobicContact CG-CD2 3.48Å; P84-L299 VanDerWaalsContact CG-CD2 3.48Å; P84-C317 HydrophobicContact CB-CB 4.35Å
85	D	92.6	Very high	93.1	Very high	3 Å²	3	16.2 Å²	16.2	2%	0.016	9%	0.093	C	C	.	.	H	α-helix	trans	-68.7	-39.7	176.5	-57.4	-97.4	0	0	0	111.4	V82 L83 Q88 F89 K210 W216 C317	V82-D85 WeakPolarHBondContact O-CB 3.47Å; V82-D85 PolarHBondContact O-N 3.42Å; V82-D85 VanDerWaalsContact O-N 3.13Å; L83-D85 VanDerWaalsContact C-N 3.28Å; L83-D85 PolarHBondContact O-N 3.3Å; D85-Q88 PolarHBondContact O-N 3.44Å; D85-F89 WeakPolarHBondContact O-CB 3.18Å; D85-F89 PolarHBondContact O-N 3.05Å; D85-K210 IonicContact OD1-NZ 3.39Å; D85-K210 WeakPolarHBondContact OD2-CD 3.42Å; D85-K210 WeakPolarHBondContact OD2-CE 3.27Å; D85-K210 IonicContact OD2-NZ 2.74Å; D85-K210 PolarHBondContact OD2-NZ 3.43Å; D85-W216 HydrophobicContact CB-CB 3.67Å; D85-W216 HydrophobicContact CB-CD2 4.5Å; D85-W216 HydrophobicContact CB-CG 3.68Å; D85-C317 WeakPolarHBondContact OD1-CB 3.38Å; D85-C317 PolarHBondContact OD1-N 3.31Å
86	I	93.3	Very high	93.3	Very high	1 Å²	1	17.3 Å²	17.3	1%	0.005	10%	0.101	C	C	.	.	H	α-helix	trans	-64.6	-44.7	175.7	-65.4	175	0	0	0	110.4	V79 V82 L83 Q88 F89 F90 I92 I100 L153 W216	V79-I86 HydrophobicContact CG1-CD1 3.78Å; V82-I86 HydrophobicContact CG2-CD1 3.95Å; V82-I86 HydrophobicContact CG2-CG1 4.35Å; V82-I86 PolarHBondContact O-N 3.18Å; L83-I86 WeakPolarHBondContact O-CB 3.23Å; L83-I86 PolarHBondContact O-N 2.94Å; L83-I86 VanDerWaalsContact O-N 3.12Å; I86-Q88 VanDerWaalsContact C-N 3.27Å; I86-Q88 PolarHBondContact O-N 3.2Å; I86-F89 PolarHBondContact O-N 3.47Å; I86-F90 HydrophobicContact CG2-CD2 3.83Å; I86-F90 HydrophobicContact CG2-CE2 4.23Å; I86-F90 WeakPolarHBondContact O-CD2 3.47Å; I86-F90 PolarHBondContact O-N 3.25Å; I86-I92 HydrophobicContact CG2-CD1 4.39Å; I86-I100 HydrophobicContact CG2-CD1 3.99Å; I86-L153 HydrophobicContact CG2-CD2 4.01Å; I86-W216 HydrophobicContact CD1-CE3 4.27Å; I86-W216 HydrophobicContact CD1-CZ3 4.03Å; I86-W216 HydrophobicContact CG1-CD2 4.24Å; I86-W216 HydrophobicContact CG1-CE3 3.76Å; I86-W216 HydrophobicContact CG1-CH2 4.07Å; I86-W216 HydrophobicContact CG1-CZ2 4.49Å; I86-W216 HydrophobicContact CG1-CZ3 3.67Å
87	E	92.8	Very high	93.5	Very high	21 Å²	21	17 Å²	17	10%	0.098	10%	0.099	C	C	.	.	H	α-helix	trans	-54.4	-47.9	177.2	-78.5	-175.3	161.7	0	0	111.2	L83 P84 S91 I92 S97 R300	L83-E87 HydrophobicContact CG-CG 4.37Å; L83-E87 WeakPolarHBondContact O-CG 3.41Å; L83-E87 PolarHBondContact O-N 3.09Å; P84-E87 PolarHBondContact O-N 3.47Å; E87-S91 CarbonylContact O-C 3.53Å; E87-S91 WeakPolarHBondContact O-CA 3.46Å; E87-S91 PolarHBondContact O-N 3.34Å; E87-I92 HydrophobicContact CB-CG1 4.48Å; E87-I92 HydrophobicContact CG-CG1 4.38Å; E87-I92 PolarHBondContact O-N 3.39Å; E87-S97 WeakPolarHBondContact CG-OG 3.45Å; E87-S97 WeakPolarHBondContact OE1-CB 3.5Å; E87-S97 PolarHBondContact OE1-OG 3.39Å; E87-R300 IonicContact OE1-NH2 2.85Å; E87-R300 PolarHBondContact OE1-NH2 3.34Å; E87-R300 IonicContact OE2-CZ 3.85Å; E87-R300 IonicContact OE2-NH2 3.49Å; E87-R300 PolarHBondContact OE2-NH2 3.21Å
88	Q	91.5	Very high	93.6	Very high	38 Å²	38	15.8 Å²	15.8	18%	0.178	9%	0.094	C	C	.	.	H	α-helix	trans	-70.1	-48.4	179.8	179.7	176.7	52.9	0	0	113	P84 D85 I86 F90 S91 C311 L312 P313 D315	P84-Q88 WeakPolarHBondContact O-CB 3.41Å; P84-Q88 PolarHBondContact O-N 3.22Å; P84-Q88 VanDerWaalsContact O-N 3.12Å; D85-Q88 PolarHBondContact O-N 3.44Å; I86-Q88 VanDerWaalsContact C-N 3.27Å; I86-Q88 PolarHBondContact O-N 3.2Å; Q88-F90 PolarHBondContact O-N 3.01Å; Q88-S91 PolarHBondContact O-N 3.03Å; Q88-S91 VanDerWaalsContact O-N 3.1Å; Q88-S91 PolarHBondContact O-OG 3.44Å; Q88-C311 PolarHBondContact NE2-O 2.97Å; Q88-L312 PolarHBondContact NE2-O 3.38Å; Q88-P313 VanDerWaalsContact NE2-N 3.11Å; Q88-D315 PolarHBondContact OE1-O 3.23Å
89	F	92.4	Very high	93.7	Very high	57 Å²	57	17.3 Å²	17.3	25%	0.25	10%	0.102	C	C	.	.	H	α-helix	trans	-59	-49.1	-176.4	179.4	-95.8	0	0	0	111.1	D85 I86 S91 R147 W216 H217	D85-F89 WeakPolarHBondContact O-CB 3.18Å; D85-F89 PolarHBondContact O-N 3.05Å; I86-F89 PolarHBondContact O-N 3.47Å; F89-S91 VanDerWaalsContact C-N 3.32Å; F89-R147 HydrophobicContact CD1-CB 4.37Å; F89-R147 VanDerWaalsContact CE1-CA 3.47Å; F89-R147 HydrophobicContact CE1-CB 3.88Å; F89-R147 HydrophobicContact CE2-CB 4.37Å; F89-R147 HydrophobicContact CZ-CB 3.88Å; F89-R147 VanDerWaalsContact O-CD 3.24Å; F89-R147 WeakPolarHBondContact O-CD 3.26Å; F89-R147 WeakPolarHBondContact O-CG 3.43Å; F89-R147 PolarHBondContact O-NE 2.97Å; F89-R147 VanDerWaalsContact O-NE 3.13Å; F89-W216 HydrophobicContact CB-CZ2 4.29Å; F89-W216 AromaticContact CD1-CZ2 3.75Å; F89-W216 HydrophobicContact CD1-CZ2 3.75Å; F89-W216 HydrophobicContact CD2-CZ2 4.49Å; F89-W216 AromaticContact CD2-NE1 3.93Å; F89-W216 HydrophobicContact CE1-CZ2 4.12Å; F89-W216 AromaticContact CG-CZ2 3.94Å; F89-W216 HydrophobicContact CG-CZ2 3.94Å; F89-W216 AromaticContact CG-NE1 3.88Å; F89-H217 AromaticContact CE2-CE1 3.82Å; F89-H217 AromaticContact CZ-CE1 3.95Å; F89-H217 AromaticContact CZ-NE2 3.77Å
90	F	93.4	Very high	93.8	Very high	16 Å²	16	17.1 Å²	17.1	7%	0.07	10%	0.101	C	C	.	.	H	α-helix	trans	-83.6	-7.4	177.3	-68.3	-78.6	0	0	0	113.5	I86 Q88 I92 I145 P146 R147 F150 L153 W216	I86-F90 HydrophobicContact CG2-CD2 3.83Å; I86-F90 HydrophobicContact CG2-CE2 4.23Å; I86-F90 WeakPolarHBondContact O-CD2 3.47Å; I86-F90 PolarHBondContact O-N 3.25Å; Q88-F90 PolarHBondContact O-N 3.01Å; F90-I92 VanDerWaalsContact C-N 3.32Å; F90-I92 HydrophobicContact CB-CG1 4.35Å; F90-I92 HydrophobicContact CB-CG2 3.69Å; F90-I92 PolarHBondContact O-N 3.23Å; F90-I145 HydrophobicContact CE1-CG2 4.07Å; F90-I145 HydrophobicContact CZ-CG2 4.09Å; F90-P146 WeakPolarHBondContact CE1-O 3.04Å; F90-R147 VanDerWaalsContact CD1-O 3.26Å; F90-R147 WeakPolarHBondContact CD1-O 3.23Å; F90-F150 HydrophobicContact CB-CB 4.35Å; F90-F150 HydrophobicContact CB-CD2 4.21Å; F90-F150 HydrophobicContact CD1-CB 3.82Å; F90-F150 HydrophobicContact CD1-CD2 4.38Å; F90-F150 HydrophobicContact CG-CB 4.27Å; F90-F150 HydrophobicContact CG-CD2 4.13Å; F90-L153 HydrophobicContact CD2-CD2 4.14Å; F90-L153 HydrophobicContact CE2-CD2 3.62Å; F90-L153 HydrophobicContact CZ-CB 4.28Å; F90-L153 HydrophobicContact CZ-CD2 4.07Å; F90-W216 HydrophobicContact CE2-CH2 4.02Å; F90-W216 HydrophobicContact CE2-CZ2 4.14Å
91	S	92.3	Very high	93.9	Very high	76 Å²	76	17.5 Å²	17.5	53%	0.531	10%	0.102	S	C	.	.	T	Hydrogen-bonded Turn	trans	54.6	47.6	-177	-52.4	0	0	0	0	112	E87 Q88 F89 R147	E87-S91 CarbonylContact O-C 3.53Å; E87-S91 WeakPolarHBondContact O-CA 3.46Å; E87-S91 PolarHBondContact O-N 3.34Å; Q88-S91 PolarHBondContact O-N 3.03Å; Q88-S91 VanDerWaalsContact O-N 3.1Å; Q88-S91 PolarHBondContact O-OG 3.44Å; F89-S91 VanDerWaalsContact C-N 3.32Å; S91-R147 PolarHBondContact OG-NH2 3.39Å
92	I	93.8	Very high	94	Very high	29 Å²	29	18.4 Å²	18.4	15%	0.149	11%	0.108	C	C	.	.			trans	-101	155.7	-174.9	57.8	170.8	0	0	0	112.3	I86 E87 F90 I100 F150	I86-I92 HydrophobicContact CG2-CD1 4.39Å; E87-I92 HydrophobicContact CB-CG1 4.48Å; E87-I92 HydrophobicContact CG-CG1 4.38Å; E87-I92 PolarHBondContact O-N 3.39Å; F90-I92 VanDerWaalsContact C-N 3.32Å; F90-I92 HydrophobicContact CB-CG1 4.35Å; F90-I92 HydrophobicContact CB-CG2 3.69Å; F90-I92 PolarHBondContact O-N 3.23Å; I92-I100 HydrophobicContact CD1-CD1 4.31Å; I92-F150 HydrophobicContact CD1-CD2 4.07Å; I92-F150 HydrophobicContact CD1-CE2 3.6Å; I92-F150 HydrophobicContact CD1-CZ 4.23Å; I92-F150 HydrophobicContact CG2-CB 4.41Å; I92-F150 HydrophobicContact CG2-CD1 4.3Å; I92-F150 HydrophobicContact CG2-CD2 3.86Å; I92-F150 HydrophobicContact CG2-CE2 4.22Å; I92-F150 HydrophobicContact CG2-CG 3.9Å
93	G	93.2	Very high	94.2	Very high	18 Å²	18	20.5 Å²	20.5	19%	0.186	12%	0.121	C	C	.	.			trans	-89.2	174.4	173.1	0	0	0	0	0	113.2	S95 S96 S97	G93-S95 VanDerWaalsContact C-N 3.28Å; G93-S95 PolarHBondContact O-N 2.93Å; G93-S96 WeakPolarHBondContact O-CB 3.28Å; G93-S96 PolarHBondContact O-N 3.37Å; G93-S97 PolarHBondContact O-N 2.95Å; G93-S97 VanDerWaalsContact O-N 3.11Å; G93-S97 PolarHBondContact O-OG 3.48Å
94	D	95.7	Very high	94.2	Very high	2 Å²	2	20.5 Å²	20.5	1%	0.011	12%	0.121	C	C	.	.	H	α-helix	trans	-64.5	-34.3	-172.3	-67.1	-3.3	0	0	0	111.7	S96 S97 G98 W293 R300 G439 S442 D443	D94-S96 VanDerWaalsContact C-N 3.3Å; D94-S96 PolarHBondContact O-N 3.4Å; D94-S97 WeakPolarHBondContact O-CB 3.46Å; D94-S97 PolarHBondContact O-N 3.23Å; D94-G98 PolarHBondContact O-N 2.93Å; D94-W293 HydrophobicContact CB-CH2 3.47Å; D94-W293 VanDerWaalsContact CB-CH2 3.47Å; D94-W293 HydrophobicContact CB-CZ2 4.19Å; D94-W293 HydrophobicContact CB-CZ3 4.07Å; D94-W293 WeakPolarHBondContact O-CH2 3.44Å; D94-W293 WeakPolarHBondContact O-CZ2 3.18Å; D94-R300 IonicContact OD1-CZ 2.73Å; D94-R300 IonicContact OD1-NH1 3.56Å; D94-R300 PolarHBondContact OD1-NH1 3.35Å; D94-R300 VanDerWaalsContact OD1-NH1 3.08Å; D94-R300 IonicContact OD1-NH2 2.99Å; D94-R300 PolarHBondContact OD1-NH2 3.15Å; D94-R300 IonicContact OD2-CZ 3.2Å; D94-R300 IonicContact OD2-NH1 2.83Å; D94-R300 PolarHBondContact OD2-NH1 2.99Å; D94-R300 IonicContact OD2-NH2 3.92Å; D94-G439 WeakPolarHBondContact O-CA 3.31Å; D94-S442 VanDerWaalsContact OD2-CB 3.24Å; D94-S442 WeakPolarHBondContact OD2-CB 3.42Å; D94-S442 PolarHBondContact OD2-OG 3.49Å; D94-D443 WeakPolarHBondContact CB-OD1 3.25Å; D94-D443 PolarHBondContact N-OD1 3.01Å; D94-D443 PolarHBondContact N-OD2 2.88Å
95	S	96.1	Very high	94.3	Very high	22 Å²	22	19.8 Å²	19.8	15%	0.154	12%	0.116	C	C	.	.	H	α-helix	trans	-60.3	-40.5	174.7	57.9	0	0	0	0	112.1	G93 G98 L99 Y436 G439 D443	G93-S95 VanDerWaalsContact C-N 3.28Å; G93-S95 PolarHBondContact O-N 2.93Å; S95-G98 PolarHBondContact O-N 2.58Å; S95-L99 WeakPolarHBondContact O-CG 3.28Å; S95-L99 PolarHBondContact O-N 3.38Å; S95-L99 VanDerWaalsContact O-N 3.08Å; S95-Y436 VanDerWaalsContact O-CD2 3.27Å; S95-Y436 WeakPolarHBondContact O-CD2 3.13Å; S95-G439 PolarHBondContact N-O 3.37Å; S95-D443 WeakPolarHBondContact CB-OD2 3.2Å; S95-D443 PolarHBondContact N-OD2 3.12Å; S95-D443 PolarHBondContact OG-OD2 3.16Å
96	S	96.2	Very high	94.3	Very high	28 Å²	28	21.5 Å²	21.5	20%	0.196	13%	0.128	C	C	.	.	H	α-helix	trans	-72.7	-37.4	179.5	-64.5	0	0	0	0	111.7	G93 D94 G98 L99 I100 F150	G93-S96 WeakPolarHBondContact O-CB 3.28Å; G93-S96 PolarHBondContact O-N 3.37Å; D94-S96 VanDerWaalsContact C-N 3.3Å; D94-S96 PolarHBondContact O-N 3.4Å; S96-G98 VanDerWaalsContact C-N 3.32Å; S96-G98 PolarHBondContact O-N 3.37Å; S96-L99 WeakPolarHBondContact O-CB 3.26Å; S96-L99 PolarHBondContact O-N 2.93Å; S96-I100 PolarHBondContact O-N 3.16Å; S96-F150 WeakPolarHBondContact O-CZ 3.24Å
97	S	96.1	Very high	94.4	Very high	0 Å²	0	22.4 Å²	22.4	0%	0	14%	0.135	C	C	.	.	H	α-helix	trans	-57.7	-45.4	169.7	-56.2	0	0	0	0	111.7	E87 G93 D94 L99 I100	E87-S97 WeakPolarHBondContact CG-OG 3.45Å; E87-S97 WeakPolarHBondContact OE1-CB 3.5Å; E87-S97 PolarHBondContact OE1-OG 3.39Å; G93-S97 PolarHBondContact O-N 2.95Å; G93-S97 VanDerWaalsContact O-N 3.11Å; G93-S97 PolarHBondContact O-OG 3.48Å; D94-S97 WeakPolarHBondContact O-CB 3.46Å; D94-S97 PolarHBondContact O-N 3.23Å; S97-L99 VanDerWaalsContact C-N 3.31Å; S97-L99 PolarHBondContact O-N 3.33Å; S97-I100 VanDerWaalsContact O-CB 3.3Å; S97-I100 WeakPolarHBondContact O-CB 3.33Å; S97-I100 PolarHBondContact O-N 2.93Å
98	G	96.1	Very high	94.3	Very high	0 Å²	0	22.8 Å²	22.8	0%	0	14%	0.136	C	C	.	.	H	α-helix	trans	-58.8	-39.3	175.2	0	0	0	0	0	113.4	D94 S95 S96 I100 Q101 T102	D94-G98 PolarHBondContact O-N 2.93Å; S95-G98 PolarHBondContact O-N 2.58Å; S96-G98 VanDerWaalsContact C-N 3.32Å; S96-G98 PolarHBondContact O-N 3.37Å; G98-I100 PolarHBondContact O-N 3.42Å; G98-Q101 PolarHBondContact O-N 3.41Å; G98-T102 PolarHBondContact O-N 3.31Å; G98-T102 VanDerWaalsContact O-N 3.16Å; G98-T102 PolarHBondContact O-OG1 3.49Å; G98-T102 VanDerWaalsContact O-OG1 3.14Å
99	L	95.9	Very high	94.3	Very high	33 Å²	33	22.5 Å²	22.5	17%	0.173	13%	0.134	C	C	.	.	H	α-helix	trans	-59.8	-32.8	178.1	-76.4	172.8	0	0	0	113.2	S95 S96 S97 Q101 T102 V103 L154 Y436	S95-L99 WeakPolarHBondContact O-CG 3.28Å; S95-L99 PolarHBondContact O-N 3.38Å; S95-L99 VanDerWaalsContact O-N 3.08Å; S96-L99 WeakPolarHBondContact O-CB 3.26Å; S96-L99 PolarHBondContact O-N 2.93Å; S97-L99 VanDerWaalsContact C-N 3.31Å; S97-L99 PolarHBondContact O-N 3.33Å; L99-Q101 VanDerWaalsContact C-N 3.28Å; L99-Q101 PolarHBondContact O-N 3.26Å; L99-T102 PolarHBondContact O-N 3.18Å; L99-V103 WeakPolarHBondContact O-CB 3.43Å; L99-V103 WeakPolarHBondContact O-CG2 3.38Å; L99-V103 PolarHBondContact O-N 3.12Å; L99-L154 HydrophobicContact CB-CD1 4.03Å; L99-L154 HydrophobicContact CB-CD2 4.49Å; L99-L154 WeakPolarHBondContact O-CD1 3.22Å; L99-Y436 HydrophobicContact CD1-CD2 4.39Å; L99-Y436 HydrophobicContact CD1-CE2 4.03Å; L99-Y436 HydrophobicContact CD2-CD2 3.49Å; L99-Y436 VanDerWaalsContact CD2-CD2 3.49Å; L99-Y436 HydrophobicContact CD2-CE2 3.62Å; L99-Y436 HydrophobicContact CD2-CG 3.97Å; L99-Y436 HydrophobicContact CG-CD2 3.48Å; L99-Y436 VanDerWaalsContact CG-CD2 3.48Å; L99-Y436 HydrophobicContact CG-CE2 3.59Å; L99-Y436 HydrophobicContact CG-CG 4.37Å
100	I	95.6	Very high	94.2	Very high	0 Å²	0	24.3 Å²	24.3	0%	0	15%	0.15	C	C	.	.	H	α-helix	trans	-55.1	-46.5	179.6	-61	177	0	0	0	110.4	V79 L83 I86 I92 S96 S97 G98 F150 L153 R157	V79-I100 HydrophobicContact CG1-CG2 3.8Å; L83-I100 HydrophobicContact CD1-CD1 4.42Å; I86-I100 HydrophobicContact CG2-CD1 3.99Å; I92-I100 HydrophobicContact CD1-CD1 4.31Å; S96-I100 PolarHBondContact O-N 3.16Å; S97-I100 VanDerWaalsContact O-CB 3.3Å; S97-I100 WeakPolarHBondContact O-CB 3.33Å; S97-I100 PolarHBondContact O-N 2.93Å; G98-I100 PolarHBondContact O-N 3.42Å; I100-F150 HydrophobicContact CD1-CE2 4.08Å; I100-F150 HydrophobicContact CG1-CE2 4.03Å; I100-F150 HydrophobicContact CG1-CZ 4.19Å; I100-L153 HydrophobicContact CD1-CD2 4.42Å; I100-R157 HydrophobicContact CG2-CG 3.83Å
101	Q	93.6	Very high	94.2	Very high	8 Å²	8	25.9 Å²	25.9	4%	0.037	16%	0.159	C	C	.	.	H	α-helix	trans	-74.1	-44.1	177.3	-168.7	65.5	20.9	0	0	111.3	G98 L99 V103 F104 I105 L292 P435	G98-Q101 PolarHBondContact O-N 3.41Å; L99-Q101 VanDerWaalsContact C-N 3.28Å; L99-Q101 PolarHBondContact O-N 3.26Å; Q101-V103 PolarHBondContact O-N 3.29Å; Q101-F104 WeakPolarHBondContact O-CB 3.39Å; Q101-F104 PolarHBondContact O-N 3.2Å; Q101-I105 HydrophobicContact CG-CD1 3.99Å; Q101-I105 HydrophobicContact CG-CG1 4.42Å; Q101-I105 WeakPolarHBondContact O-CG1 3.49Å; Q101-I105 PolarHBondContact O-N 3.24Å; Q101-L292 HydrophobicContact CB-CD1 4.47Å; Q101-L292 HydrophobicContact CB-CD2 4.24Å; Q101-P435 HydrophobicContact CB-CB 4.38Å; Q101-P435 HydrophobicContact CB-CG 4.27Å; Q101-P435 HydrophobicContact CG-CG 4.17Å
102	T	94.5	Very high	94	Very high	20 Å²	20	23 Å²	23	12%	0.123	14%	0.14	C	C	.	.	H	α-helix	trans	-58.9	-46.8	-177.8	-60.5	0	0	0	0	112.8	G98 L99 F104 I105 S106 A432 Y436	G98-T102 PolarHBondContact O-N 3.31Å; G98-T102 VanDerWaalsContact O-N 3.16Å; G98-T102 PolarHBondContact O-OG1 3.49Å; G98-T102 VanDerWaalsContact O-OG1 3.14Å; L99-T102 PolarHBondContact O-N 3.18Å; T102-F104 VanDerWaalsContact C-N 3.35Å; T102-I105 PolarHBondContact O-N 2.87Å; T102-S106 VanDerWaalsContact O-CB 3.23Å; T102-S106 WeakPolarHBondContact O-CB 3.37Å; T102-S106 PolarHBondContact O-N 3.39Å; T102-S106 PolarHBondContact O-OG 2.84Å; T102-A432 WeakPolarHBondContact CA-O 3.41Å; T102-A432 WeakPolarHBondContact CB-O 3.39Å; T102-A432 VanDerWaalsContact CG2-O 3.22Å; T102-A432 WeakPolarHBondContact CG2-O 3.33Å; T102-A432 PolarHBondContact OG1-O 3.11Å; T102-Y436 WeakPolarHBondContact OG1-CB 3.33Å
103	V	96	Very high	93.7	Very high	43 Å²	43	25.9 Å²	25.9	26%	0.261	16%	0.16	S	C	.	.	H	α-helix	trans	-66.2	-40.8	-179.2	169	0	0	0	0	110.9	L99 Q101 S107 L154	L99-V103 WeakPolarHBondContact O-CB 3.43Å; L99-V103 WeakPolarHBondContact O-CG2 3.38Å; L99-V103 PolarHBondContact O-N 3.12Å; Q101-V103 PolarHBondContact O-N 3.29Å; V103-S107 WeakPolarHBondContact O-CB 3.45Å; V103-S107 PolarHBondContact O-N 3.26Å; V103-S107 PolarHBondContact O-OG 2.72Å; V103-S107 VanDerWaalsContact O-OG 3.08Å; V103-L154 HydrophobicContact CB-CD1 3.79Å; V103-L154 HydrophobicContact CB-CG 4.17Å; V103-L154 HydrophobicContact CG1-CD1 4.33Å; V103-L154 HydrophobicContact CG1-CG 4.25Å; V103-L154 HydrophobicContact CG2-CD1 3.63Å; V103-L154 HydrophobicContact CG2-CD2 4.01Å; V103-L154 HydrophobicContact CG2-CG 3.83Å
104	F	95.2	Very high	93.5	Very high	0 Å²	0	28.5 Å²	28.5	0%	0	17%	0.172	C	C	.	.	H	α-helix	trans	-58	-53.6	174.4	168.1	-87.7	0	0	0	111.4	R76 Q101 T102 S106 S107 Y108 R157 V160 E164	R76-F104 HydrophobicContact CB-CZ 4.5Å; R76-F104 HydrophobicContact CG-CD1 4.49Å; R76-F104 HydrophobicContact CG-CE1 3.71Å; R76-F104 HydrophobicContact CG-CZ 4Å; Q101-F104 WeakPolarHBondContact O-CB 3.39Å; Q101-F104 PolarHBondContact O-N 3.2Å; T102-F104 VanDerWaalsContact C-N 3.35Å; F104-S106 PolarHBondContact O-N 2.75Å; F104-S107 PolarHBondContact O-N 3.01Å; F104-S107 PolarHBondContact O-OG 3.31Å; F104-Y108 WeakPolarHBondContact O-CB 3.45Å; F104-Y108 PolarHBondContact O-N 2.75Å; F104-Y108 VanDerWaalsContact O-N 3.09Å; F104-R157 HydrophobicContact CB-CB 4.41Å; F104-R157 WeakPolarHBondContact CD2-O 3.46Å; F104-V160 HydrophobicContact CD2-CB 4.39Å; F104-V160 HydrophobicContact CD2-CG1 4.34Å; F104-V160 HydrophobicContact CE2-CB 4.41Å; F104-V160 HydrophobicContact CE2-CG1 3.92Å; F104-E164 HydrophobicContact CE2-CG 4.43Å; F104-E164 WeakPolarHBondContact CE2-OE1 3.39Å; F104-E164 VanDerWaalsContact CZ-OE2 3.27Å; F104-E164 WeakPolarHBondContact CZ-OE2 3.24Å
105	I	93.3	Very high	93.1	Very high	1 Å²	1	30.1 Å²	30.1	1%	0.005	18%	0.179	C	C	.	.	H	α-helix	trans	-68.2	-38.1	-177.5	-57.9	-177.6	0	0	0	111.5	Q101 T102 Y108 M109 H427 D431 A432	Q101-I105 HydrophobicContact CG-CD1 3.99Å; Q101-I105 HydrophobicContact CG-CG1 4.42Å; Q101-I105 WeakPolarHBondContact O-CG1 3.49Å; Q101-I105 PolarHBondContact O-N 3.24Å; T102-I105 PolarHBondContact O-N 2.87Å; I105-Y108 WeakPolarHBondContact O-CB 3.46Å; I105-Y108 PolarHBondContact O-N 3.32Å; I105-M109 WeakPolarHBondContact O-CB 3.49Å; I105-M109 PolarHBondContact O-N 3.25Å; I105-H427 HydrophobicContact CG2-CB 4.27Å; I105-D431 HydrophobicContact CD1-CB 4.04Å; I105-D431 WeakPolarHBondContact CD1-O 3.5Å; I105-A432 HydrophobicContact CB-CB 3.79Å; I105-A432 HydrophobicContact CG2-CB 3.64Å
106	S	93.9	Very high	92.4	Very high	38 Å²	38	30.2 Å²	30.2	27%	0.266	18%	0.184	S	C	.	.	H	α-helix	trans	-64	-44.8	179.5	-60.2	0	0	0	0	111.5	T102 F104 M109 V110	T102-S106 VanDerWaalsContact O-CB 3.23Å; T102-S106 WeakPolarHBondContact O-CB 3.37Å; T102-S106 PolarHBondContact O-N 3.39Å; T102-S106 PolarHBondContact O-OG 2.84Å; F104-S106 PolarHBondContact O-N 2.75Å; S106-M109 PolarHBondContact O-N 2.7Å; S106-V110 WeakPolarHBondContact O-CG2 3.4Å; S106-V110 PolarHBondContact O-N 2.96Å; S106-V110 VanDerWaalsContact O-N 3.09Å
107	S	94.5	Very high	91.5	Very high	20 Å²	20	34.8 Å²	34.8	14%	0.14	20%	0.198	C	C	.	.	H	α-helix	trans	-63	-43.3	176.5	67.5	0	0	0	0	112	V103 F104 M109 V110 L111 G158	V103-S107 WeakPolarHBondContact O-CB 3.45Å; V103-S107 PolarHBondContact O-N 3.26Å; V103-S107 PolarHBondContact O-OG 2.72Å; V103-S107 VanDerWaalsContact O-OG 3.08Å; F104-S107 PolarHBondContact O-N 3.01Å; F104-S107 PolarHBondContact O-OG 3.31Å; S107-M109 PolarHBondContact O-N 3.49Å; S107-V110 PolarHBondContact O-N 3.31Å; S107-L111 WeakPolarHBondContact O-CD2 3.33Å; S107-L111 PolarHBondContact O-N 2.99Å; S107-L111 VanDerWaalsContact O-N 3.12Å; S107-G158 WeakPolarHBondContact CB-O 3.29Å; S107-G158 WeakPolarHBondContact OG-CA 3.23Å; S107-G158 PolarHBondContact OG-O 2.87Å
108	Y	92	Very high	90.9	Very high	30 Å²	30	36.9 Å²	36.9	12%	0.118	21%	0.209	C	C	.	.	H	α-helix	trans	-55.3	-49.8	173.3	170.8	-87	0	0	0	111.7	F104 I105 V110 L111 A112 E164 A165 S168	F104-Y108 WeakPolarHBondContact O-CB 3.45Å; F104-Y108 PolarHBondContact O-N 2.75Å; F104-Y108 VanDerWaalsContact O-N 3.09Å; I105-Y108 WeakPolarHBondContact O-CB 3.46Å; I105-Y108 PolarHBondContact O-N 3.32Å; Y108-V110 PolarHBondContact O-N 2.85Å; Y108-L111 PolarHBondContact O-N 3.11Å; Y108-A112 VanDerWaalsContact O-CB 3.28Å; Y108-A112 WeakPolarHBondContact O-CB 3.29Å; Y108-A112 PolarHBondContact O-N 3.39Å; Y108-E164 HydrophobicContact CD2-CB 4.38Å; Y108-A165 HydrophobicContact CD2-CB 3.83Å; Y108-A165 HydrophobicContact CE2-CB 4.23Å; Y108-A165 HydrophobicContact CG-CB 4.4Å; Y108-S168 WeakPolarHBondContact OH-CB 3.15Å
109	M	90.9	Very high	90.3	Very high	31 Å²	31	37 Å²	37	15%	0.153	21%	0.21	C	C	.	.	H	α-helix	trans	-65.3	-39.1	-176.1	-172.8	-176.9	65.8	0	0	112.7	I105 S106 S107 P113 V424 H427 L428	I105-M109 WeakPolarHBondContact O-CB 3.49Å; I105-M109 PolarHBondContact O-N 3.25Å; S106-M109 PolarHBondContact O-N 2.7Å; S107-M109 PolarHBondContact O-N 3.49Å; M109-P113 VanDerWaalsContact O-CD 3.26Å; M109-P113 WeakPolarHBondContact O-CD 3.33Å; M109-V424 HydrophobicContact SD-CB 4.48Å; M109-V424 HydrophobicContact SD-CG1 4.07Å; M109-H427 HydrophobicContact SD-CB 3.91Å; M109-L428 HydrophobicContact CE-CB 3.96Å; M109-L428 HydrophobicContact CE-CD1 4.01Å; M109-L428 HydrophobicContact CE-CG 4.41Å; M109-L428 HydrophobicContact SD-CB 3.98Å
110	V	91.1	Very high	89.4	Confident	95 Å²	95	40.3 Å²	40.3	58%	0.576	23%	0.228	S	C	*	.	H	α-helix	trans	-71.6	-35.3	179.9	176.3	0	0	0	0	111.5	S106 S107 Y108	S106-V110 WeakPolarHBondContact O-CG2 3.4Å; S106-V110 PolarHBondContact O-N 2.96Å; S106-V110 VanDerWaalsContact O-N 3.09Å; S107-V110 PolarHBondContact O-N 3.31Å; Y108-V110 PolarHBondContact O-N 2.85Å
111	L	92.3	Very high	88.7	Confident	50 Å²	50	46.3 Å²	46.3	26%	0.262	25%	0.25	S	S	.	.	H	α-helix	trans	-91.6	-18.3	-176.1	-82.7	-61.8	0	0	0	113.8	S107 Y108 V114 F115 V162 A165	S107-L111 WeakPolarHBondContact O-CD2 3.33Å; S107-L111 PolarHBondContact O-N 2.99Å; S107-L111 VanDerWaalsContact O-N 3.12Å; Y108-L111 PolarHBondContact O-N 3.11Å; L111-V114 HydrophobicContact CD1-CB 4.29Å; L111-V114 HydrophobicContact CD1-CG2 4.17Å; L111-V114 WeakPolarHBondContact O-CB 3.25Å; L111-V114 PolarHBondContact O-N 3.04Å; L111-F115 HydrophobicContact CB-CD2 4.25Å; L111-F115 HydrophobicContact CB-CE2 4.24Å; L111-F115 WeakPolarHBondContact O-CD2 3.11Å; L111-F115 PolarHBondContact O-N 3.15Å; L111-V162 HydrophobicContact CD2-CG2 4.22Å; L111-V162 HydrophobicContact CG-CG1 4.15Å; L111-V162 HydrophobicContact CG-CG2 4.01Å; L111-A165 HydrophobicContact CB-CB 4.32Å
112	A	88.8	Confident	88.4	Confident	16 Å²	16	52.5 Å²	52.5	13%	0.132	27%	0.274	C	S	.	.	H	α-helix	trans	-53.5	-47.3	176.6	0	0	0	0	0	113.4	Y108 V114 F115 G116 A165 T169	Y108-A112 VanDerWaalsContact O-CB 3.28Å; Y108-A112 WeakPolarHBondContact O-CB 3.29Å; Y108-A112 PolarHBondContact O-N 3.39Å; A112-V114 VanDerWaalsContact C-N 3.26Å; A112-V114 PolarHBondContact O-N 2.93Å; A112-F115 PolarHBondContact O-N 3.41Å; A112-G116 PolarHBondContact O-N 2.67Å; A112-A165 HydrophobicContact CB-CB 4.43Å; A112-T169 HydrophobicContact CB-CG2 3.56Å
113	P	86.6	Confident	88.2	Confident	89 Å²	89	54.1 Å²	54.1	58%	0.578	28%	0.283	S	S	*	.	H	α-helix	trans	-59.9	-34.9	175.3	-24.9	34.6	0	0	0	113.7	M109 G116 Y117	M109-P113 VanDerWaalsContact O-CD 3.26Å; M109-P113 WeakPolarHBondContact O-CD 3.33Å; P113-G116 PolarHBondContact O-N 3.32Å; P113-Y117 PolarHBondContact O-N 3.35Å
114	V	88.8	Confident	87.9	Confident	72 Å²	72	52.4 Å²	52.4	44%	0.436	27%	0.271	S	S	.	.	H	α-helix	trans	-66.5	-47.4	178.1	-178.3	0	0	0	0	110	L111 A112 G116 Y117 L118	L111-V114 HydrophobicContact CD1-CB 4.29Å; L111-V114 HydrophobicContact CD1-CG2 4.17Å; L111-V114 WeakPolarHBondContact O-CB 3.25Å; L111-V114 PolarHBondContact O-N 3.04Å; A112-V114 VanDerWaalsContact C-N 3.26Å; A112-V114 PolarHBondContact O-N 2.93Å; V114-G116 VanDerWaalsContact C-N 3.35Å; V114-G116 PolarHBondContact O-N 3.13Å; V114-Y117 WeakPolarHBondContact O-CB 3.21Å; V114-Y117 PolarHBondContact O-N 3.45Å; V114-L118 HydrophobicContact CG1-CD1 4.21Å; V114-L118 VanDerWaalsContact O-CG 3.3Å; V114-L118 WeakPolarHBondContact O-CG 3.17Å; V114-L118 PolarHBondContact O-N 3.43Å
115	F	87.8	Confident	87.8	Confident	36 Å²	36	53.8 Å²	53.8	16%	0.158	28%	0.277	C	S	.	.	H	α-helix	trans	-69.4	-30.1	177.1	-77.2	-70.1	0	0	0	113.6	L111 A112 L118 G119 V162 A165 S166	L111-F115 HydrophobicContact CB-CD2 4.25Å; L111-F115 HydrophobicContact CB-CE2 4.24Å; L111-F115 WeakPolarHBondContact O-CD2 3.11Å; L111-F115 PolarHBondContact O-N 3.15Å; A112-F115 PolarHBondContact O-N 3.41Å; F115-L118 HydrophobicContact CD1-CD1 4.17Å; F115-L118 HydrophobicContact CE1-CD1 4.41Å; F115-L118 PolarHBondContact O-N 2.89Å; F115-G119 PolarHBondContact O-N 3.09Å; F115-V162 HydrophobicContact CE2-CG1 4.02Å; F115-V162 WeakPolarHBondContact CE2-O 3.25Å; F115-V162 HydrophobicContact CZ-CG1 4.36Å; F115-A165 HydrophobicContact CD2-CB 3.94Å; F115-A165 HydrophobicContact CE2-CB 4.4Å; F115-S166 VanDerWaalsContact CD1-CB 3.41Å
116	G	80.8	Confident	87.8	Confident	24 Å²	24	60.1 Å²	60.1	25%	0.247	30%	0.302	C	S	.	.	H	α-helix	trans	-59	-52.4	167.9	0	0	0	0	0	111.5	A112 P113 V114 L118 G119 D120	A112-G116 PolarHBondContact O-N 2.67Å; P113-G116 PolarHBondContact O-N 3.32Å; V114-G116 VanDerWaalsContact C-N 3.35Å; V114-G116 PolarHBondContact O-N 3.13Å; G116-L118 VanDerWaalsContact C-N 3.29Å; G116-L118 PolarHBondContact O-N 3.36Å; G116-G119 PolarHBondContact O-N 2.91Å; G116-G119 VanDerWaalsContact O-N 3.13Å; G116-D120 PolarHBondContact O-N 3.27Å; G116-D120 VanDerWaalsContact O-N 3.09Å
117	Y	78.8	Confident	87.8	Confident	125 Å²	125	59.9 Å²	59.9	49%	0.49	30%	0.298	S	S	.	.	H	α-helix	trans	-57.3	-40.7	176.1	174.3	-85.2	0	0	0	113.1	P113 V114 R121	P113-Y117 PolarHBondContact O-N 3.35Å; V114-Y117 WeakPolarHBondContact O-CB 3.21Å; V114-Y117 PolarHBondContact O-N 3.45Å; Y117-R121 VanDerWaalsContact CZ-NE 3.27Å; Y117-R121 PolarHBondContact O-NH1 2.99Å; Y117-R121 PolarHBondContact OH-NE 3.12Å; Y117-R121 VanDerWaalsContact OH-NE 3.16Å
118	L	82.9	Confident	87.9	Confident	43 Å²	43	59 Å²	59	23%	0.225	29%	0.291	C	S	.	.	H	α-helix	trans	-69.3	-41.1	177	-68.3	174.8	0	0	0	111.3	V114 F115 G116 D120 R121 Y122 L127	V114-L118 HydrophobicContact CG1-CD1 4.21Å; V114-L118 VanDerWaalsContact O-CG 3.3Å; V114-L118 WeakPolarHBondContact O-CG 3.17Å; V114-L118 PolarHBondContact O-N 3.43Å; F115-L118 HydrophobicContact CD1-CD1 4.17Å; F115-L118 HydrophobicContact CE1-CD1 4.41Å; F115-L118 PolarHBondContact O-N 2.89Å; G116-L118 VanDerWaalsContact C-N 3.29Å; G116-L118 PolarHBondContact O-N 3.36Å; L118-D120 VanDerWaalsContact C-N 3.26Å; L118-D120 PolarHBondContact O-N 3.45Å; L118-R121 PolarHBondContact O-N 2.92Å; L118-R121 VanDerWaalsContact O-N 3.09Å; L118-Y122 HydrophobicContact CB-CD2 4.23Å; L118-Y122 HydrophobicContact CD2-CD2 3.69Å; L118-Y122 HydrophobicContact CD2-CE2 3.49Å; L118-Y122 VanDerWaalsContact CD2-CE2 3.49Å; L118-Y122 WeakPolarHBondContact O-CD2 3.25Å; L118-Y122 PolarHBondContact O-N 3.24Å; L118-L127 HydrophobicContact CB-CD1 4.02Å; L118-L127 HydrophobicContact CB-CD2 4.4Å; L118-L127 WeakPolarHBondContact O-CD1 3.16Å
119	G	82.3	Confident	88.1	Confident	3 Å²	3	58.1 Å²	58.1	3%	0.031	29%	0.29	C	S	.	.	H	α-helix	trans	-60.1	-34.9	177.5	0	0	0	0	0	113.3	F115 G116 R121 R124	F115-G119 PolarHBondContact O-N 3.09Å; G116-G119 PolarHBondContact O-N 2.91Å; G116-G119 VanDerWaalsContact O-N 3.13Å; G119-R121 VanDerWaalsContact C-N 3.26Å; G119-R121 PolarHBondContact O-N 3.49Å; G119-R124 WeakPolarHBondContact O-CG 3.28Å
120	D	77.3	Confident	88.3	Confident	102 Å²	102	58.7 Å²	58.7	55%	0.545	30%	0.303	S	S	.	.	H	α-helix	trans	-69.5	-23.1	176.8	-68.1	-20	0	0	0	113.4	G116 L118 R243	G116-D120 PolarHBondContact O-N 3.27Å; G116-D120 VanDerWaalsContact O-N 3.09Å; L118-D120 VanDerWaalsContact C-N 3.26Å; L118-D120 PolarHBondContact O-N 3.45Å; D120-R243 PolarHBondContact O-NH1 3.45Å
121	R	81.7	Confident	88.5	Confident	126 Å²	126	54.4 Å²	54.4	48%	0.475	28%	0.279	S	S	.	.	H	α-helix	trans	-109.7	-45.1	-172	-74.1	173.6	176.7	70.1	2.7	112.8	Y117 L118 G119 R243	Y117-R121 VanDerWaalsContact CZ-NE 3.27Å; Y117-R121 PolarHBondContact O-NH1 2.99Å; Y117-R121 PolarHBondContact OH-NE 3.12Å; Y117-R121 VanDerWaalsContact OH-NE 3.16Å; L118-R121 PolarHBondContact O-N 2.92Å; L118-R121 VanDerWaalsContact O-N 3.09Å; G119-R121 VanDerWaalsContact C-N 3.26Å; G119-R121 PolarHBondContact O-N 3.49Å; R121-R243 VanDerWaalsContact C-NH2 3.27Å; R121-R243 PolarHBondContact O-NH1 3.48Å; R121-R243 PolarHBondContact O-NH2 3.36Å
122	Y	87.8	Confident	88.7	Confident	138 Å²	138	52 Å²	52	54%	0.541	27%	0.266	S	S	.	.	S	Bend	trans	-103.3	159.3	-175.2	-57.1	-83.3	0	0	0	112	L118 R124 R243	L118-Y122 HydrophobicContact CB-CD2 4.23Å; L118-Y122 HydrophobicContact CD2-CD2 3.69Å; L118-Y122 HydrophobicContact CD2-CE2 3.49Å; L118-Y122 VanDerWaalsContact CD2-CE2 3.49Å; L118-Y122 WeakPolarHBondContact O-CD2 3.25Å; L118-Y122 PolarHBondContact O-N 3.24Å; Y122-R124 PolarHBondContact O-N 3.46Å; Y122-R124 VanDerWaalsContact O-N 3.12Å; Y122-R243 PolarHBondContact O-NH2 2.92Å
123	N	89.4	Confident	89.1	Confident	55 Å²	55	53 Å²	53	29%	0.294	27%	0.274	S	S	.	.			trans	-57.9	118.9	-176.3	-177.3	-59.8	0	0	0	110.7	K125 Y126 L127	N123-K125 PolarHBondContact O-N 3.44Å; N123-K125 VanDerWaalsContact OD1-CB 3.3Å; N123-K125 WeakPolarHBondContact OD1-CB 3.29Å; N123-K125 PolarHBondContact OD1-N 2.85Å; N123-Y126 HydrophobicContact CB-CD2 3.72Å; N123-Y126 HydrophobicContact CB-CE2 4.38Å; N123-Y126 VanDerWaalsContact CG-CD2 3.49Å; N123-Y126 PolarHBondContact O-N 2.94Å; N123-Y126 PolarHBondContact OD1-N 3.02Å; N123-L127 PolarHBondContact O-N 3.03Å; N123-L127 VanDerWaalsContact O-N 3.16Å
124	R	89.7	Confident	89.5	Confident	7 Å²	7	52.8 Å²	52.8	3%	0.026	26%	0.264	C	S	.	.	H	α-helix	trans	-66.3	-40.2	-171.3	-71.4	179	-69.4	-165.9	-6.8	111.6	G119 Y122 Y126 L127 M128 I170 T173 D177 E240	G119-R124 WeakPolarHBondContact O-CG 3.28Å; Y122-R124 PolarHBondContact O-N 3.46Å; Y122-R124 VanDerWaalsContact O-N 3.12Å; R124-Y126 PolarHBondContact O-N 2.71Å; R124-L127 PolarHBondContact O-N 3.4Å; R124-M128 WeakPolarHBondContact O-CG 3.21Å; R124-M128 PolarHBondContact O-N 2.97Å; R124-I170 HydrophobicContact CB-CG2 3.42Å; R124-I170 VanDerWaalsContact CB-CG2 3.42Å; R124-I170 HydrophobicContact CG-CG2 3.53Å; R124-T173 PolarHBondContact NH1-O 3.39Å; R124-T173 PolarHBondContact NH1-OG1 3.37Å; R124-D177 IonicContact CZ-OD2 2.58Å; R124-D177 IonicContact NH1-OD2 3.38Å; R124-D177 PolarHBondContact NH1-OD2 2.98Å; R124-D177 IonicContact NH2-OD2 3.31Å; R124-D177 PolarHBondContact NH2-OD2 2.9Å; R124-E240 WeakPolarHBondContact CB-OE2 3.33Å; R124-E240 IonicContact CZ-OE1 2.7Å; R124-E240 PolarHBondContact N-OE2 3.47Å; R124-E240 IonicContact NE-OE1 2.82Å; R124-E240 PolarHBondContact NE-OE1 3.16Å; R124-E240 IonicContact NH2-OE1 3.49Å; R124-E240 PolarHBondContact NH2-OE1 3.35Å
125	K	93.1	Very high	89.9	Confident	28 Å²	28	49.9 Å²	49.9	12%	0.122	25%	0.245	C	C	.	.	H	α-helix	trans	-52.2	-51.2	173.6	177.7	-170.6	-178.5	165.2	0	112.1	N123 M128 C129 L234 F235 V238 E240	N123-K125 PolarHBondContact O-N 3.44Å; N123-K125 VanDerWaalsContact OD1-CB 3.3Å; N123-K125 WeakPolarHBondContact OD1-CB 3.29Å; N123-K125 PolarHBondContact OD1-N 2.85Å; K125-M128 PolarHBondContact O-N 3.49Å; K125-C129 PolarHBondContact O-N 3.23Å; K125-L234 HydrophobicContact CG-CD2 3.82Å; K125-L234 WeakPolarHBondContact O-CD2 3.47Å; K125-F235 WeakPolarHBondContact CE-O 3.46Å; K125-F235 PolarHBondContact NZ-O 3.08Å; K125-V238 VanDerWaalsContact CD-O 3.28Å; K125-V238 WeakPolarHBondContact CD-O 3.31Å; K125-V238 WeakPolarHBondContact CE-O 3.49Å; K125-V238 PolarHBondContact NZ-O 3.22Å; K125-E240 PolarHBondContact N-OE2 3.01Å; K125-E240 VanDerWaalsContact N-OE2 3.11Å
126	Y	94.4	Very high	90.3	Very high	134 Å²	134	48.6 Å²	48.6	53%	0.525	24%	0.241	S	C	.	.	H	α-helix	trans	-70.8	-35.5	-177.7	-63.2	-49.1	0	0	0	113.2	N123 R124 C129 G130 F235	N123-Y126 HydrophobicContact CB-CD2 3.72Å; N123-Y126 HydrophobicContact CB-CE2 4.38Å; N123-Y126 VanDerWaalsContact CG-CD2 3.49Å; N123-Y126 PolarHBondContact O-N 2.94Å; N123-Y126 PolarHBondContact OD1-N 3.02Å; R124-Y126 PolarHBondContact O-N 2.71Å; Y126-C129 PolarHBondContact O-N 3.3Å; Y126-G130 PolarHBondContact O-N 3.41Å; Y126-F235 HydrophobicContact CD1-CE2 4.45Å; Y126-F235 HydrophobicContact CE1-CD2 4.38Å; Y126-F235 AromaticContact CE1-CE2 3.81Å; Y126-F235 HydrophobicContact CE1-CE2 3.81Å
127	L	93.9	Very high	91	Very high	34 Å²	34	53.3 Å²	53.3	18%	0.178	26%	0.26	C	S	.	.	H	α-helix	trans	-60.6	-46.1	172.8	-74.3	172.5	0	0	0	111.4	L118 N123 R124 G130 G131 I170	L118-L127 HydrophobicContact CB-CD1 4.02Å; L118-L127 HydrophobicContact CB-CD2 4.4Å; L118-L127 WeakPolarHBondContact O-CD1 3.16Å; N123-L127 PolarHBondContact O-N 3.03Å; N123-L127 VanDerWaalsContact O-N 3.16Å; R124-L127 PolarHBondContact O-N 3.4Å; L127-G130 PolarHBondContact O-N 3.39Å; L127-G131 PolarHBondContact O-N 3.25Å; L127-I170 HydrophobicContact CB-CD1 3.69Å; L127-I170 HydrophobicContact CD1-CD1 3.81Å; L127-I170 HydrophobicContact CG-CD1 4.42Å
128	M	95.1	Very high	91.9	Very high	0 Å²	0	48.2 Å²	48.2	0%	0	24%	0.242	C	C	.	.	H	α-helix	trans	-64.2	-45.1	176.2	-69.8	-172.7	-68.6	0	0	111.8	L65 R124 K125 G130 G131 I132 Y167 I170 A171 L174 L234	L65-M128 HydrophobicContact CD2-CE 4.4Å; L65-M128 HydrophobicContact CD2-SD 4.27Å; R124-M128 WeakPolarHBondContact O-CG 3.21Å; R124-M128 PolarHBondContact O-N 2.97Å; K125-M128 PolarHBondContact O-N 3.49Å; M128-G130 VanDerWaalsContact C-N 3.32Å; M128-G130 PolarHBondContact O-N 3.25Å; M128-G131 PolarHBondContact O-N 2.89Å; M128-I132 HydrophobicContact CB-CD1 4.46Å; M128-I132 WeakPolarHBondContact O-CB 3.33Å; M128-I132 VanDerWaalsContact O-CD1 3.31Å; M128-I132 WeakPolarHBondContact O-CD1 3.42Å; M128-I132 WeakPolarHBondContact O-CG1 3.4Å; M128-I132 PolarHBondContact O-N 3.39Å; M128-Y167 HydrophobicContact CB-CD2 4.5Å; M128-Y167 HydrophobicContact CG-CD2 4.21Å; M128-Y167 HydrophobicContact SD-CD2 3.89Å; M128-Y167 HydrophobicContact SD-CE2 4.04Å; M128-I170 HydrophobicContact CE-CG2 4.3Å; M128-I170 HydrophobicContact CG-CB 4.09Å; M128-I170 HydrophobicContact CG-CG2 3.87Å; M128-I170 HydrophobicContact SD-CB 4.34Å; M128-I170 HydrophobicContact SD-CG2 3.94Å; M128-A171 HydrophobicContact SD-CB 4.17Å; M128-L174 HydrophobicContact CE-CD2 3.69Å; M128-L234 HydrophobicContact CB-CD1 3.92Å; M128-L234 HydrophobicContact CB-CD2 4.19Å; M128-L234 HydrophobicContact CE-CD1 4.02Å; M128-L234 HydrophobicContact SD-CD1 4.2Å
129	C	96	Very high	92.5	Very high	13 Å²	13	46.3 Å²	46.3	9%	0.088	23%	0.232	C	C	.	.	H	α-helix	trans	-55.3	-47.7	174.4	-79	0	0	0	0	111.9	K125 Y126 I132 A133 L234	K125-C129 PolarHBondContact O-N 3.23Å; Y126-C129 PolarHBondContact O-N 3.3Å; C129-I132 PolarHBondContact O-N 2.96Å; C129-A133 VanDerWaalsContact O-CB 3.29Å; C129-A133 WeakPolarHBondContact O-CB 3.46Å; C129-A133 PolarHBondContact O-N 3.31Å; C129-L234 HydrophobicContact CB-CD2 4.42Å; C129-L234 WeakPolarHBondContact SG-CD2 3.31Å
130	G	96.1	Very high	93.1	Very high	42 Å²	42	49.2 Å²	49.2	43%	0.433	25%	0.246	S	C	.	.	H	α-helix	trans	-62.8	-43.5	179.8	0	0	0	0	0	112.1	Y126 L127 M128 F134	Y126-G130 PolarHBondContact O-N 3.41Å; L127-G130 PolarHBondContact O-N 3.39Å; M128-G130 VanDerWaalsContact C-N 3.32Å; M128-G130 PolarHBondContact O-N 3.25Å; G130-F134 WeakPolarHBondContact O-CB 3.31Å; G130-F134 PolarHBondContact O-N 2.57Å
131	G	95.6	Very high	94	Very high	6 Å²	6	46 Å²	46	6%	0.062	24%	0.238	C	C	.	.	H	α-helix	trans	-60.3	-52.1	174.4	0	0	0	0	0	113.4	L127 M128 A133 F134 W135 S166	L127-G131 PolarHBondContact O-N 3.25Å; M128-G131 PolarHBondContact O-N 2.89Å; G131-A133 VanDerWaalsContact C-N 3.34Å; G131-A133 PolarHBondContact O-N 2.89Å; G131-F134 PolarHBondContact O-N 2.98Å; G131-F134 VanDerWaalsContact O-N 3.16Å; G131-W135 PolarHBondContact O-N 2.91Å; G131-S166 VanDerWaalsContact CA-OG 3.32Å; G131-S166 WeakPolarHBondContact CA-OG 3.32Å
132	I	95.9	Very high	94.6	Very high	0 Å²	0	40.3 Å²	40.3	0%	0	22%	0.217	C	C	.	.	H	α-helix	trans	-57.5	-48.2	179	-60.7	154.1	0	0	0	110.7	I68 M128 C129 F134 W135 S136 A230 V231 L234	I68-I132 HydrophobicContact CD1-CD1 4.15Å; I68-I132 HydrophobicContact CG2-CD1 4.08Å; I68-I132 HydrophobicContact CG2-CG1 4.23Å; M128-I132 HydrophobicContact CB-CD1 4.46Å; M128-I132 WeakPolarHBondContact O-CB 3.33Å; M128-I132 VanDerWaalsContact O-CD1 3.31Å; M128-I132 WeakPolarHBondContact O-CD1 3.42Å; M128-I132 WeakPolarHBondContact O-CG1 3.4Å; M128-I132 PolarHBondContact O-N 3.39Å; C129-I132 PolarHBondContact O-N 2.96Å; I132-F134 VanDerWaalsContact C-N 3.34Å; I132-F134 PolarHBondContact O-N 3.48Å; I132-W135 VanDerWaalsContact CA-CD2 3.48Å; I132-W135 HydrophobicContact CB-CD2 4.48Å; I132-W135 HydrophobicContact CB-CE3 4.35Å; I132-W135 HydrophobicContact CB-CH2 3.71Å; I132-W135 HydrophobicContact CB-CZ2 3.78Å; I132-W135 HydrophobicContact CB-CZ3 3.97Å; I132-W135 HydrophobicContact CD1-CH2 4.3Å; I132-W135 HydrophobicContact CG1-CE3 4.38Å; I132-W135 HydrophobicContact CG1-CH2 3.04Å; I132-W135 HydrophobicContact CG1-CZ2 3.5Å; I132-W135 VanDerWaalsContact CG1-CZ2 3.5Å; I132-W135 HydrophobicContact CG1-CZ3 3.52Å; I132-W135 HydrophobicContact CG2-CH2 4.09Å; I132-W135 HydrophobicContact CG2-CZ2 3.62Å; I132-S136 VanDerWaalsContact O-CB 3.23Å; I132-S136 WeakPolarHBondContact O-CB 3.49Å; I132-S136 PolarHBondContact O-N 2.69Å; I132-S136 PolarHBondContact O-OG 2.99Å; I132-A230 HydrophobicContact CG2-CB 4.41Å; I132-V231 HydrophobicContact CB-CG2 3.71Å; I132-V231 HydrophobicContact CG2-CG2 3.36Å; I132-L234 HydrophobicContact CD1-CD1 3.85Å
133	A	96.4	Very high	95	Very high	37 Å²	37	33.8 Å²	33.8	31%	0.306	19%	0.192	S	C	.	.	H	α-helix	trans	-61.8	-44.1	177.8	0	0	0	0	0	111.3	C129 G131 S136 L137 V231	C129-A133 VanDerWaalsContact O-CB 3.29Å; C129-A133 WeakPolarHBondContact O-CB 3.46Å; C129-A133 PolarHBondContact O-N 3.31Å; G131-A133 VanDerWaalsContact C-N 3.34Å; G131-A133 PolarHBondContact O-N 2.89Å; A133-S136 PolarHBondContact O-N 3.15Å; A133-L137 WeakPolarHBondContact O-CB 3.11Å; A133-L137 WeakPolarHBondContact O-CG 3.29Å; A133-L137 PolarHBondContact O-N 3.35Å; A133-V231 HydrophobicContact CB-CG2 4.39Å
134	F	96.9	Very high	95.2	Very high	83 Å²	83	37.6 Å²	37.6	36%	0.364	21%	0.206	S	C	.	.	H	α-helix	trans	-61.9	-52.8	179.6	-179.4	-107.6	0	0	0	112.1	G130 G131 I132 S136 L137 V138 L159	G130-F134 WeakPolarHBondContact O-CB 3.31Å; G130-F134 PolarHBondContact O-N 2.57Å; G131-F134 PolarHBondContact O-N 2.98Å; G131-F134 VanDerWaalsContact O-N 3.16Å; I132-F134 VanDerWaalsContact C-N 3.34Å; I132-F134 PolarHBondContact O-N 3.48Å; F134-S136 VanDerWaalsContact C-N 3.31Å; F134-S136 PolarHBondContact O-N 3.01Å; F134-L137 PolarHBondContact O-N 2.84Å; F134-V138 HydrophobicContact CD1-CG2 4.47Å; F134-V138 HydrophobicContact CD2-CG2 4.29Å; F134-V138 HydrophobicContact CE1-CG2 4.16Å; F134-V138 HydrophobicContact CE2-CG2 3.95Å; F134-V138 HydrophobicContact CZ-CG2 3.88Å; F134-V138 VanDerWaalsContact O-CG2 3.25Å; F134-V138 WeakPolarHBondContact O-CG2 3.36Å; F134-V138 PolarHBondContact O-N 3.28Å; F134-L159 HydrophobicContact CE1-CB 4.21Å; F134-L159 VanDerWaalsContact CE1-O 3.31Å; F134-L159 WeakPolarHBondContact CE1-O 3.42Å; F134-L159 HydrophobicContact CZ-CB 4.18Å; F134-L159 HydrophobicContact CZ-CD2 4.21Å
135	W	96.1	Very high	95.5	Very high	11 Å²	11	37.7 Å²	37.7	4%	0.042	21%	0.207	C	C	.	.	H	α-helix	trans	-65.1	-37.7	-179.9	80.8	68	0	0	0	111.4	I68 G131 I132 L137 V138 T139 V160 G163 E164 Y167	I68-W135 HydrophobicContact CG2-CH2 4.17Å; I68-W135 HydrophobicContact CG2-CZ2 4.34Å; G131-W135 PolarHBondContact O-N 2.91Å; I132-W135 VanDerWaalsContact CA-CD2 3.48Å; I132-W135 HydrophobicContact CB-CD2 4.48Å; I132-W135 HydrophobicContact CB-CE3 4.35Å; I132-W135 HydrophobicContact CB-CH2 3.71Å; I132-W135 HydrophobicContact CB-CZ2 3.78Å; I132-W135 HydrophobicContact CB-CZ3 3.97Å; I132-W135 HydrophobicContact CD1-CH2 4.3Å; I132-W135 HydrophobicContact CG1-CE3 4.38Å; I132-W135 HydrophobicContact CG1-CH2 3.04Å; I132-W135 HydrophobicContact CG1-CZ2 3.5Å; I132-W135 VanDerWaalsContact CG1-CZ2 3.5Å; I132-W135 HydrophobicContact CG1-CZ3 3.52Å; I132-W135 HydrophobicContact CG2-CH2 4.09Å; I132-W135 HydrophobicContact CG2-CZ2 3.62Å; W135-L137 VanDerWaalsContact C-N 3.34Å; W135-L137 PolarHBondContact O-N 3.4Å; W135-V138 PolarHBondContact O-N 3.49Å; W135-T139 WeakPolarHBondContact O-CB 3.47Å; W135-T139 PolarHBondContact O-N 3.16Å; W135-T139 PolarHBondContact O-OG1 2.96Å; W135-T139 VanDerWaalsContact O-OG1 3.05Å; W135-V160 HydrophobicContact CB-CG1 4.15Å; W135-G163 VanDerWaalsContact CE3-C 3.46Å; W135-E164 HydrophobicContact CD2-CG 4.24Å; W135-E164 HydrophobicContact CE3-CG 4.27Å; W135-E164 HydrophobicContact CG-CG 4.39Å; W135-Y167 HydrophobicContact CH2-CG 4.05Å; W135-Y167 HydrophobicContact CZ3-CG 4.46Å
136	S	95.8	Very high	95.4	Very high	9 Å²	9	39 Å²	39	6%	0.063	22%	0.218	C	C	.	.	H	α-helix	trans	-63.8	-41.7	180	-60.4	0	0	0	0	111.2	I132 A133 F134 L140 P224	I132-S136 VanDerWaalsContact O-CB 3.23Å; I132-S136 WeakPolarHBondContact O-CB 3.49Å; I132-S136 PolarHBondContact O-N 2.69Å; I132-S136 PolarHBondContact O-OG 2.99Å; A133-S136 PolarHBondContact O-N 3.15Å; F134-S136 VanDerWaalsContact C-N 3.31Å; F134-S136 PolarHBondContact O-N 3.01Å; S136-L140 WeakPolarHBondContact O-CB 3.41Å; S136-L140 PolarHBondContact O-N 2.8Å; S136-P224 WeakPolarHBondContact O-CB 3.49Å; S136-P224 WeakPolarHBondContact O-CG 3.47Å
137	L	96.6	Very high	95.2	Very high	123 Å²	123	38.8 Å²	38.8	64%	0.644	22%	0.217	S	C	*	.	H	α-helix	trans	-66.3	-42.2	175.8	-73.2	170.6	0	0	0	112.1	A133 F134 W135 L140 G141	A133-L137 WeakPolarHBondContact O-CB 3.11Å; A133-L137 WeakPolarHBondContact O-CG 3.29Å; A133-L137 PolarHBondContact O-N 3.35Å; F134-L137 PolarHBondContact O-N 2.84Å; W135-L137 VanDerWaalsContact C-N 3.34Å; W135-L137 PolarHBondContact O-N 3.4Å; L137-L140 PolarHBondContact O-N 2.9Å; L137-G141 PolarHBondContact O-N 3.29Å
138	V	96.9	Very high	95.1	Very high	19 Å²	19	44.6 Å²	44.6	12%	0.115	24%	0.243	C	C	.	.	H	α-helix	trans	-67	-43.7	178.3	173.9	0	0	0	0	111	F134 W135 G141 S142 T156 L159 V160	F134-V138 HydrophobicContact CD1-CG2 4.47Å; F134-V138 HydrophobicContact CD2-CG2 4.29Å; F134-V138 HydrophobicContact CE1-CG2 4.16Å; F134-V138 HydrophobicContact CE2-CG2 3.95Å; F134-V138 HydrophobicContact CZ-CG2 3.88Å; F134-V138 VanDerWaalsContact O-CG2 3.25Å; F134-V138 WeakPolarHBondContact O-CG2 3.36Å; F134-V138 PolarHBondContact O-N 3.28Å; W135-V138 PolarHBondContact O-N 3.49Å; V138-G141 PolarHBondContact O-N 3.4Å; V138-S142 PolarHBondContact O-N 3.17Å; V138-T156 HydrophobicContact CG1-CG2 4.18Å; V138-T156 VanDerWaalsContact CG1-O 3.3Å; V138-T156 WeakPolarHBondContact CG1-O 3.38Å; V138-L159 HydrophobicContact CG1-CB 3.73Å; V138-L159 HydrophobicContact CG2-CB 4.19Å; V138-V160 HydrophobicContact CB-CG2 4.13Å; V138-V160 HydrophobicContact CG1-CG2 3.67Å
139	T	95.4	Very high	95	Very high	2 Å²	2	52 Å²	52	1%	0.012	27%	0.271	C	S	.	.	H	α-helix	trans	-60.4	-45.8	174.9	-63.5	0	0	0	0	110.5	D75 W135 G141 S142 S143 V160 L220 P224	D75-T139 WeakPolarHBondContact OD1-CG2 3.35Å; D75-T139 PolarHBondContact OD2-OG1 3.43Å; W135-T139 WeakPolarHBondContact O-CB 3.47Å; W135-T139 PolarHBondContact O-N 3.16Å; W135-T139 PolarHBondContact O-OG1 2.96Å; W135-T139 VanDerWaalsContact O-OG1 3.05Å; T139-G141 PolarHBondContact O-N 2.94Å; T139-S142 WeakPolarHBondContact O-CB 3.46Å; T139-S142 PolarHBondContact O-N 3.47Å; T139-S142 VanDerWaalsContact O-N 3.16Å; T139-S142 PolarHBondContact O-OG 2.9Å; T139-S143 PolarHBondContact O-N 3.38Å; T139-V160 VanDerWaalsContact OG1-CG2 3.26Å; T139-V160 WeakPolarHBondContact OG1-CG2 3Å; T139-L220 HydrophobicContact CG2-CB 4.46Å; T139-P224 HydrophobicContact CG2-CG 3.99Å
140	L	95.9	Very high	94.9	Very high	64 Å²	64	52.2 Å²	52.2	34%	0.335	27%	0.27	S	S	.	.	H	α-helix	trans	-59.8	-46.3	174.8	-178.5	58.7	0	0	0	111.6	S136 L137 S142 S143 F144 R221 P224	S136-L140 WeakPolarHBondContact O-CB 3.41Å; S136-L140 PolarHBondContact O-N 2.8Å; L137-L140 PolarHBondContact O-N 2.9Å; L140-S142 VanDerWaalsContact C-N 3.25Å; L140-S142 PolarHBondContact O-N 3.48Å; L140-S143 WeakPolarHBondContact O-CB 3.43Å; L140-S143 PolarHBondContact O-N 2.87Å; L140-S143 VanDerWaalsContact O-N 3.13Å; L140-S143 PolarHBondContact O-OG 3.34Å; L140-F144 HydrophobicContact CD1-CE2 4.02Å; L140-F144 HydrophobicContact CG-CE2 4.12Å; L140-F144 WeakPolarHBondContact O-CD2 3.48Å; L140-F144 WeakPolarHBondContact O-CE2 3.45Å; L140-R221 HydrophobicContact CD1-CB 4.39Å; L140-R221 HydrophobicContact CD1-CG 4Å; L140-P224 HydrophobicContact CB-CB 4Å; L140-P224 HydrophobicContact CB-CG 3.8Å
141	G	95.8	Very high	94.9	Very high	36 Å²	36	59 Å²	59	37%	0.371	28%	0.283	S	S	.	.	H	α-helix	trans	-59	-35.2	176.3	0	0	0	0	0	113.1	L137 V138 T139 S143 F144	L137-G141 PolarHBondContact O-N 3.29Å; V138-G141 PolarHBondContact O-N 3.4Å; T139-G141 PolarHBondContact O-N 2.94Å; G141-S143 PolarHBondContact O-N 3.37Å; G141-F144 PolarHBondContact O-N 3.33Å; G141-F144 VanDerWaalsContact O-N 3.15Å
142	S	94.7	Very high	94.9	Very high	5 Å²	5	62.3 Å²	62.3	4%	0.035	30%	0.298	C	S	.	.	H	α-helix	trans	-63.5	-27.1	178.1	80.1	0	0	0	0	113.2	V138 T139 L140 F144 I145 T156	V138-S142 PolarHBondContact O-N 3.17Å; T139-S142 WeakPolarHBondContact O-CB 3.46Å; T139-S142 PolarHBondContact O-N 3.47Å; T139-S142 VanDerWaalsContact O-N 3.16Å; T139-S142 PolarHBondContact O-OG 2.9Å; L140-S142 VanDerWaalsContact C-N 3.25Å; L140-S142 PolarHBondContact O-N 3.48Å; S142-F144 PolarHBondContact O-N 3.49Å; S142-I145 WeakPolarHBondContact O-CG1 3.38Å; S142-I145 PolarHBondContact O-N 3.33Å; S142-T156 WeakPolarHBondContact CB-OG1 3.5Å
143	S	94.4	Very high	94.8	Very high	1 Å²	1	62.5 Å²	62.5	1%	0.007	30%	0.299	C	S	.	.	T	Hydrogen-bonded Turn	trans	-73.1	-2.9	176.9	82	0	0	0	0	114.8	T139 L140 G141 H217 R221	T139-S143 PolarHBondContact O-N 3.38Å; L140-S143 WeakPolarHBondContact O-CB 3.43Å; L140-S143 PolarHBondContact O-N 2.87Å; L140-S143 VanDerWaalsContact O-N 3.13Å; L140-S143 PolarHBondContact O-OG 3.34Å; G141-S143 PolarHBondContact O-N 3.37Å; S143-H217 PolarHBondContact O-CD2 3.22Å; S143-R221 PolarHBondContact O-NH2 2.62Å; S143-R221 VanDerWaalsContact O-NH2 3.11Å; S143-R221 VanDerWaalsContact OG-CG 3.3Å; S143-R221 WeakPolarHBondContact OG-CG 3.45Å; S143-R221 PolarHBondContact OG-NE 3.13Å; S143-R221 VanDerWaalsContact OG-NE 3.08Å
144	F	95.1	Very high	94.8	Very high	135 Å²	135	61.3 Å²	61.3	59%	0.592	29%	0.288	S	S	*	.	T	Hydrogen-bonded Turn	trans	-113.2	8.8	178.2	-60.7	-76.2	0	0	0	112.6	L140 G141 S142 P146	L140-F144 HydrophobicContact CD1-CE2 4.02Å; L140-F144 HydrophobicContact CG-CE2 4.12Å; L140-F144 WeakPolarHBondContact O-CD2 3.48Å; L140-F144 WeakPolarHBondContact O-CE2 3.45Å; G141-F144 PolarHBondContact O-N 3.33Å; G141-F144 VanDerWaalsContact O-N 3.15Å; S142-F144 PolarHBondContact O-N 3.49Å; F144-P146 WeakPolarHBondContact O-CD 3.33Å
145	I	94.9	Very high	94.8	Very high	9 Å²	9	62.1 Å²	62.1	5%	0.046	30%	0.295	C	S	.	.			trans	-73.9	125.9	-176.1	-66.6	176.6	0	0	0	110.1	F90 S142 R149 L152 L153 T156	F90-I145 HydrophobicContact CE1-CG2 4.07Å; F90-I145 HydrophobicContact CZ-CG2 4.09Å; S142-I145 WeakPolarHBondContact O-CG1 3.38Å; S142-I145 PolarHBondContact O-N 3.33Å; I145-R149 HydrophobicContact CG2-CB 4.09Å; I145-R149 WeakPolarHBondContact CG2-O 3.22Å; I145-L152 HydrophobicContact CD1-CB 4.32Å; I145-L152 HydrophobicContact CD1-CD2 4.44Å; I145-L152 HydrophobicContact CD1-CG 3.97Å; I145-L152 HydrophobicContact CG1-CD2 4.16Å; I145-L152 HydrophobicContact CG1-CG 4.24Å; I145-L152 HydrophobicContact CG2-CB 4.22Å; I145-L152 HydrophobicContact CG2-CD2 4.38Å; I145-L153 VanDerWaalsContact CD1-CA 3.46Å; I145-L153 HydrophobicContact CD1-CB 4.05Å; I145-L153 HydrophobicContact CD1-CD1 4.21Å; I145-T156 HydrophobicContact CD1-CG2 3.89Å
146	P	92.1	Very high	94.8	Very high	56 Å²	56	62.4 Å²	62.4	36%	0.364	30%	0.298	S	S	.	.			trans	-65.1	152.5	176.4	-21.1	32.8	0	0	0	112.9	F90 F144 E148 R149	F90-P146 WeakPolarHBondContact CE1-O 3.04Å; F144-P146 WeakPolarHBondContact O-CD 3.33Å; P146-E148 VanDerWaalsContact CB-OE2 3.27Å; P146-E148 WeakPolarHBondContact CB-OE2 3.16Å; P146-E148 PolarHBondContact O-N 3.23Å; P146-R149 PolarHBondContact O-N 3.21Å
147	R	90.3	Very high	94.9	Very high	130 Å²	130	62.3 Å²	62.3	49%	0.491	30%	0.297	S	S	.	.	T	Hydrogen-bonded Turn	trans	-50	-33.8	178.8	165.4	166.7	-170	-156.2	1.3	114.3	F89 F90 S91 R149	F89-R147 HydrophobicContact CD1-CB 4.37Å; F89-R147 VanDerWaalsContact CE1-CA 3.47Å; F89-R147 HydrophobicContact CE1-CB 3.88Å; F89-R147 HydrophobicContact CE2-CB 4.37Å; F89-R147 HydrophobicContact CZ-CB 3.88Å; F89-R147 VanDerWaalsContact O-CD 3.24Å; F89-R147 WeakPolarHBondContact O-CD 3.26Å; F89-R147 WeakPolarHBondContact O-CG 3.43Å; F89-R147 PolarHBondContact O-NE 2.97Å; F89-R147 VanDerWaalsContact O-NE 3.13Å; F90-R147 VanDerWaalsContact CD1-O 3.26Å; F90-R147 WeakPolarHBondContact CD1-O 3.23Å; S91-R147 PolarHBondContact OG-NH2 3.39Å; R147-R149 PolarHBondContact O-N 3.3Å
148	E	90.4	Very high	94.9	Very high	155 Å²	155	56.9 Å²	56.9	72%	0.724	27%	0.27	S	S	*	.	T	Hydrogen-bonded Turn	trans	-79	-8.1	-175.3	-51	74.1	-156.2	0	0	112.7	P146	P146-E148 VanDerWaalsContact CB-OE2 3.27Å; P146-E148 WeakPolarHBondContact CB-OE2 3.16Å; P146-E148 PolarHBondContact O-N 3.23Å
149	R	93.6	Very high	94.9	Very high	156 Å²	156	59 Å²	59	59%	0.589	28%	0.281	S	S	*	.			trans	-117.2	49.9	-168	-60.8	-172.7	-175.3	-95.2	0.5	113.3	I145 P146 R147 W151 L152 L153	I145-R149 HydrophobicContact CG2-CB 4.09Å; I145-R149 WeakPolarHBondContact CG2-O 3.22Å; P146-R149 PolarHBondContact O-N 3.21Å; R147-R149 PolarHBondContact O-N 3.3Å; R149-W151 VanDerWaalsContact C-N 3.26Å; R149-W151 PolarHBondContact O-N 2.93Å; R149-L152 HydrophobicContact CB-CB 4.02Å; R149-L152 VanDerWaalsContact O-CB 3.28Å; R149-L152 WeakPolarHBondContact O-CB 3.31Å; R149-L152 PolarHBondContact O-N 3.13Å; R149-L153 PolarHBondContact O-N 3.46Å
150	F	94.4	Very high	94.9	Very high	18 Å²	18	58.9 Å²	58.9	8%	0.079	28%	0.28	C	S	.	.	H	α-helix	trans	-51.7	-41.9	175.1	172.3	-107.6	0	0	0	113.6	F90 I92 S96 I100 L152 L153 L154	F90-F150 HydrophobicContact CB-CB 4.35Å; F90-F150 HydrophobicContact CB-CD2 4.21Å; F90-F150 HydrophobicContact CD1-CB 3.82Å; F90-F150 HydrophobicContact CD1-CD2 4.38Å; F90-F150 HydrophobicContact CG-CB 4.27Å; F90-F150 HydrophobicContact CG-CD2 4.13Å; I92-F150 HydrophobicContact CD1-CD2 4.07Å; I92-F150 HydrophobicContact CD1-CE2 3.6Å; I92-F150 HydrophobicContact CD1-CZ 4.23Å; I92-F150 HydrophobicContact CG2-CB 4.41Å; I92-F150 HydrophobicContact CG2-CD1 4.3Å; I92-F150 HydrophobicContact CG2-CD2 3.86Å; I92-F150 HydrophobicContact CG2-CE2 4.22Å; I92-F150 HydrophobicContact CG2-CG 3.9Å; S96-F150 WeakPolarHBondContact O-CZ 3.24Å; I100-F150 HydrophobicContact CD1-CE2 4.08Å; I100-F150 HydrophobicContact CG1-CE2 4.03Å; I100-F150 HydrophobicContact CG1-CZ 4.19Å; F150-L152 PolarHBondContact O-N 3.07Å; F150-L153 HydrophobicContact CD2-CD2 4.46Å; F150-L153 WeakPolarHBondContact O-CA 3.45Å; F150-L153 VanDerWaalsContact O-CB 3.29Å; F150-L153 WeakPolarHBondContact O-CB 3.36Å; F150-L153 PolarHBondContact O-N 3.15Å; F150-L154 PolarHBondContact O-N 3.31Å
151	W	94.7	Very high	94.9	Very high	185 Å²	185	55.9 Å²	55.9	70%	0.701	26%	0.264	S	S	*	.	H	α-helix	trans	-61.8	-27.1	178.4	-66.9	107.5	0	0	0	113.6	R149 L154 L155	R149-W151 VanDerWaalsContact C-N 3.26Å; R149-W151 PolarHBondContact O-N 2.93Å; W151-L154 HydrophobicContact CE3-CD2 3.64Å; W151-L154 HydrophobicContact CZ3-CD2 3.55Å; W151-L154 PolarHBondContact O-N 3.12Å; W151-L155 PolarHBondContact O-N 3.03Å
152	L	96	Very high	94.9	Very high	74 Å²	74	55.7 Å²	55.7	39%	0.387	26%	0.256	S	S	.	.	H	α-helix	trans	-70.9	-38.2	173.2	-172.3	60.9	0	0	0	110.7	I145 R149 F150 L154 L155 T156	I145-L152 HydrophobicContact CD1-CB 4.32Å; I145-L152 HydrophobicContact CD1-CD2 4.44Å; I145-L152 HydrophobicContact CD1-CG 3.97Å; I145-L152 HydrophobicContact CG1-CD2 4.16Å; I145-L152 HydrophobicContact CG1-CG 4.24Å; I145-L152 HydrophobicContact CG2-CB 4.22Å; I145-L152 HydrophobicContact CG2-CD2 4.38Å; R149-L152 HydrophobicContact CB-CB 4.02Å; R149-L152 VanDerWaalsContact O-CB 3.28Å; R149-L152 WeakPolarHBondContact O-CB 3.31Å; R149-L152 PolarHBondContact O-N 3.13Å; F150-L152 PolarHBondContact O-N 3.07Å; L152-L154 VanDerWaalsContact C-N 3.31Å; L152-L154 PolarHBondContact O-N 3.31Å; L152-L155 HydrophobicContact CD1-CD2 4.25Å; L152-L155 PolarHBondContact O-N 3.17Å; L152-T156 WeakPolarHBondContact O-CG2 2.99Å; L152-T156 PolarHBondContact O-N 3.05Å; L152-T156 PolarHBondContact O-OG1 3.44Å
153	L	95.2	Very high	94.8	Very high	4 Å²	4	55.5 Å²	55.5	2%	0.021	26%	0.255	C	S	.	.	H	α-helix	trans	-60	-46.7	172.6	179.9	70.1	0	0	0	109.7	I86 F90 I100 I145 R149 F150 L155 T156 R157	I86-L153 HydrophobicContact CG2-CD2 4.01Å; F90-L153 HydrophobicContact CD2-CD2 4.14Å; F90-L153 HydrophobicContact CE2-CD2 3.62Å; F90-L153 HydrophobicContact CZ-CB 4.28Å; F90-L153 HydrophobicContact CZ-CD2 4.07Å; I100-L153 HydrophobicContact CD1-CD2 4.42Å; I145-L153 VanDerWaalsContact CD1-CA 3.46Å; I145-L153 HydrophobicContact CD1-CB 4.05Å; I145-L153 HydrophobicContact CD1-CD1 4.21Å; R149-L153 PolarHBondContact O-N 3.46Å; F150-L153 HydrophobicContact CD2-CD2 4.46Å; F150-L153 WeakPolarHBondContact O-CA 3.45Å; F150-L153 VanDerWaalsContact O-CB 3.29Å; F150-L153 WeakPolarHBondContact O-CB 3.36Å; F150-L153 PolarHBondContact O-N 3.15Å; L153-L155 VanDerWaalsContact C-N 3.33Å; L153-L155 PolarHBondContact O-N 3.09Å; L153-T156 WeakPolarHBondContact CA-OG1 3.49Å; L153-T156 PolarHBondContact O-N 3.47Å; L153-T156 VanDerWaalsContact O-N 3.15Å; L153-T156 PolarHBondContact O-OG1 2.9Å; L153-R157 WeakPolarHBondContact O-CG 3.49Å; L153-R157 PolarHBondContact O-N 3.36Å
154	L	95.8	Very high	94.8	Very high	13 Å²	13	55.5 Å²	55.5	7%	0.068	26%	0.255	C	S	.	.	H	α-helix	trans	-59.9	-42.4	178	-166.1	65.4	0	0	0	112.4	L99 V103 F150 W151 L152 R157 G158	L99-L154 HydrophobicContact CB-CD1 4.03Å; L99-L154 HydrophobicContact CB-CD2 4.49Å; L99-L154 WeakPolarHBondContact O-CD1 3.22Å; V103-L154 HydrophobicContact CB-CD1 3.79Å; V103-L154 HydrophobicContact CB-CG 4.17Å; V103-L154 HydrophobicContact CG1-CD1 4.33Å; V103-L154 HydrophobicContact CG1-CG 4.25Å; V103-L154 HydrophobicContact CG2-CD1 3.63Å; V103-L154 HydrophobicContact CG2-CD2 4.01Å; V103-L154 HydrophobicContact CG2-CG 3.83Å; F150-L154 PolarHBondContact O-N 3.31Å; W151-L154 HydrophobicContact CE3-CD2 3.64Å; W151-L154 HydrophobicContact CZ3-CD2 3.55Å; W151-L154 PolarHBondContact O-N 3.12Å; L152-L154 VanDerWaalsContact C-N 3.31Å; L152-L154 PolarHBondContact O-N 3.31Å; L154-R157 PolarHBondContact O-N 3.26Å; L154-G158 PolarHBondContact O-N 3.46Å
155	L	97	Very high	94.7	Very high	99 Å²	99	49 Å²	49	52%	0.518	23%	0.227	S	C	.	.	H	α-helix	trans	-60.7	-47.7	173.8	177.7	63.5	0	0	0	111.2	W151 L152 L153 R157 G158 L159	W151-L155 PolarHBondContact O-N 3.03Å; L152-L155 HydrophobicContact CD1-CD2 4.25Å; L152-L155 PolarHBondContact O-N 3.17Å; L153-L155 VanDerWaalsContact C-N 3.33Å; L153-L155 PolarHBondContact O-N 3.09Å; L155-R157 VanDerWaalsContact C-N 3.28Å; L155-R157 PolarHBondContact O-N 2.89Å; L155-G158 PolarHBondContact O-N 2.83Å; L155-G158 VanDerWaalsContact O-N 3.13Å; L155-L159 HydrophobicContact CD1-CG 4.46Å; L155-L159 HydrophobicContact CG-CD1 4.3Å; L155-L159 WeakPolarHBondContact O-CG 3.36Å; L155-L159 PolarHBondContact O-N 3.46Å
156	T	96.8	Very high	94.6	Very high	17 Å²	17	48.6 Å²	48.6	10%	0.104	22%	0.224	C	C	.	.	H	α-helix	trans	-60.5	-38.4	177.6	57.9	0	0	0	0	111.8	V138 S142 I145 L152 L153 G158 L159 V160	V138-T156 HydrophobicContact CG1-CG2 4.18Å; V138-T156 VanDerWaalsContact CG1-O 3.3Å; V138-T156 WeakPolarHBondContact CG1-O 3.38Å; S142-T156 WeakPolarHBondContact CB-OG1 3.5Å; I145-T156 HydrophobicContact CD1-CG2 3.89Å; L152-T156 WeakPolarHBondContact O-CG2 2.99Å; L152-T156 PolarHBondContact O-N 3.05Å; L152-T156 PolarHBondContact O-OG1 3.44Å; L153-T156 WeakPolarHBondContact CA-OG1 3.49Å; L153-T156 PolarHBondContact O-N 3.47Å; L153-T156 VanDerWaalsContact O-N 3.15Å; L153-T156 PolarHBondContact O-OG1 2.9Å; T156-G158 PolarHBondContact O-N 3.08Å; T156-L159 PolarHBondContact O-N 3.04Å; T156-L159 VanDerWaalsContact O-N 3.12Å; T156-V160 WeakPolarHBondContact O-CG2 3.11Å; T156-V160 PolarHBondContact O-N 3.23Å
157	R	96.1	Very high	94.7	Very high	7 Å²	7	46 Å²	46	3%	0.026	21%	0.207	C	C	.	.	H	α-helix	trans	-62.1	-40	174.1	-69.8	-58.2	-56.8	148.5	-2.6	112.9	D75 I100 F104 L153 L154 L155 V160 G161	D75-R157 IonicContact OD2-NH1 3.2Å; I100-R157 HydrophobicContact CG2-CG 3.83Å; F104-R157 HydrophobicContact CB-CB 4.41Å; F104-R157 WeakPolarHBondContact CD2-O 3.46Å; L153-R157 WeakPolarHBondContact O-CG 3.49Å; L153-R157 PolarHBondContact O-N 3.36Å; L154-R157 PolarHBondContact O-N 3.26Å; L155-R157 VanDerWaalsContact C-N 3.28Å; L155-R157 PolarHBondContact O-N 2.89Å; R157-V160 PolarHBondContact O-N 3.17Å; R157-G161 PolarHBondContact O-N 3.38Å; R157-G161 VanDerWaalsContact O-N 3.09Å
158	G	96.9	Very high	94.7	Very high	9 Å²	9	40.7 Å²	40.7	9%	0.093	19%	0.19	C	C	.	.	H	α-helix	trans	-61.6	-44.2	170.9	0	0	0	0	0	112.2	S107 L154 L155 T156 V160 G161 V162	S107-G158 WeakPolarHBondContact CB-O 3.29Å; S107-G158 WeakPolarHBondContact OG-CA 3.23Å; S107-G158 PolarHBondContact OG-O 2.87Å; L154-G158 PolarHBondContact O-N 3.46Å; L155-G158 PolarHBondContact O-N 2.83Å; L155-G158 VanDerWaalsContact O-N 3.13Å; T156-G158 PolarHBondContact O-N 3.08Å; G158-V160 PolarHBondContact O-N 3.4Å; G158-G161 PolarHBondContact O-N 2.92Å; G158-G161 VanDerWaalsContact O-N 3.17Å; G158-V162 WeakPolarHBondContact O-CG2 3.27Å; G158-V162 PolarHBondContact O-N 3.22Å
159	L	97.1	Very high	94.5	Very high	63 Å²	63	34.9 Å²	34.9	33%	0.33	17%	0.165	S	C	.	.	H	α-helix	trans	-65.5	-37.1	178.1	-66.5	177.2	0	0	0	112.8	F134 V138 L155 T156 G161 V162 G163	F134-L159 HydrophobicContact CE1-CB 4.21Å; F134-L159 VanDerWaalsContact CE1-O 3.31Å; F134-L159 WeakPolarHBondContact CE1-O 3.42Å; F134-L159 HydrophobicContact CZ-CB 4.18Å; F134-L159 HydrophobicContact CZ-CD2 4.21Å; V138-L159 HydrophobicContact CG1-CB 3.73Å; V138-L159 HydrophobicContact CG2-CB 4.19Å; L155-L159 HydrophobicContact CD1-CG 4.46Å; L155-L159 HydrophobicContact CG-CD1 4.3Å; L155-L159 WeakPolarHBondContact O-CG 3.36Å; L155-L159 PolarHBondContact O-N 3.46Å; T156-L159 PolarHBondContact O-N 3.04Å; T156-L159 VanDerWaalsContact O-N 3.12Å; L159-G161 VanDerWaalsContact C-N 3.33Å; L159-V162 WeakPolarHBondContact O-CB 3.25Å; L159-V162 PolarHBondContact O-N 3.09Å; L159-G163 PolarHBondContact O-N 3.28Å; L159-G163 VanDerWaalsContact O-N 3.08Å
160	V	96.6	Very high	94.4	Very high	1 Å²	1	27.6 Å²	27.6	1%	0.006	14%	0.138	C	C	.	.	H	α-helix	trans	-60	-45.6	171.3	178.2	0	0	0	0	109.9	F104 W135 V138 T139 T156 R157 G158 V162 G163 E164	F104-V160 HydrophobicContact CD2-CB 4.39Å; F104-V160 HydrophobicContact CD2-CG1 4.34Å; F104-V160 HydrophobicContact CE2-CB 4.41Å; F104-V160 HydrophobicContact CE2-CG1 3.92Å; W135-V160 HydrophobicContact CB-CG1 4.15Å; V138-V160 HydrophobicContact CB-CG2 4.13Å; V138-V160 HydrophobicContact CG1-CG2 3.67Å; T139-V160 VanDerWaalsContact OG1-CG2 3.26Å; T139-V160 WeakPolarHBondContact OG1-CG2 3Å; T156-V160 WeakPolarHBondContact O-CG2 3.11Å; T156-V160 PolarHBondContact O-N 3.23Å; R157-V160 PolarHBondContact O-N 3.17Å; G158-V160 PolarHBondContact O-N 3.4Å; V160-V162 VanDerWaalsContact C-N 3.29Å; V160-V162 PolarHBondContact O-N 3.34Å; V160-G163 PolarHBondContact O-N 3.11Å; V160-E164 HydrophobicContact CG1-CG 4.24Å; V160-E164 WeakPolarHBondContact O-CG 3.19Å; V160-E164 PolarHBondContact O-N 3.2Å
161	G	95.4	Very high	94.3	Very high	0 Å²	0	26.7 Å²	26.7	0%	0	13%	0.134	C	C	.	.	H	α-helix	trans	-58.3	-37.4	176.3	0	0	0	0	0	113.6	R157 G158 L159 A165	R157-G161 PolarHBondContact O-N 3.38Å; R157-G161 VanDerWaalsContact O-N 3.09Å; G158-G161 PolarHBondContact O-N 2.92Å; G158-G161 VanDerWaalsContact O-N 3.17Å; L159-G161 VanDerWaalsContact C-N 3.33Å; G161-A165 WeakPolarHBondContact O-CB 3.39Å; G161-A165 PolarHBondContact O-N 3.42Å
162	V	95.1	Very high	94	Very high	33 Å²	33	18.9 Å²	18.9	20%	0.2	11%	0.107	C	C	.	.	H	α-helix	trans	-62.3	-46.6	172	174.8	0	0	0	0	111.6	L111 F115 G158 L159 V160 A165	L111-V162 HydrophobicContact CD2-CG2 4.22Å; L111-V162 HydrophobicContact CG-CG1 4.15Å; L111-V162 HydrophobicContact CG-CG2 4.01Å; F115-V162 HydrophobicContact CE2-CG1 4.02Å; F115-V162 WeakPolarHBondContact CE2-O 3.25Å; F115-V162 HydrophobicContact CZ-CG1 4.36Å; G158-V162 WeakPolarHBondContact O-CG2 3.27Å; G158-V162 PolarHBondContact O-N 3.22Å; L159-V162 WeakPolarHBondContact O-CB 3.25Å; L159-V162 PolarHBondContact O-N 3.09Å; V160-V162 VanDerWaalsContact C-N 3.29Å; V160-V162 PolarHBondContact O-N 3.34Å; V162-A165 WeakPolarHBondContact O-CB 3.29Å; V162-A165 PolarHBondContact O-N 3.23Å
163	G	93.8	Very high	93.5	Very high	1 Å²	1	17.8 Å²	17.8	1%	0.01	10%	0.103	C	C	.	.	H	α-helix	trans	-63	-46.2	178.5	0	0	0	0	0	111.9	W135 L159 V160 A165 S166	W135-G163 VanDerWaalsContact CE3-C 3.46Å; L159-G163 PolarHBondContact O-N 3.28Å; L159-G163 VanDerWaalsContact O-N 3.08Å; V160-G163 PolarHBondContact O-N 3.11Å; G163-A165 VanDerWaalsContact C-N 3.3Å; G163-A165 PolarHBondContact O-N 3.13Å; G163-S166 WeakPolarHBondContact O-CB 3.3Å; G163-S166 PolarHBondContact O-N 3.5Å; G163-S166 PolarHBondContact O-OG 3.16Å
164	E	94.4	Very high	93.1	Very high	0 Å²	0	17.6 Å²	17.6	0%	0	10%	0.102	C	C	.	.	H	α-helix	trans	-64.2	-33.2	-179.9	-73.3	-165.3	-153	0	0	113.3	N72 F104 Y108 W135 V160 S166 Y167 S168	N72-E164 WeakPolarHBondContact ND2-CB 3.23Å; N72-E164 WeakPolarHBondContact ND2-CG 3.36Å; N72-E164 PolarHBondContact ND2-OE2 2.94Å; N72-E164 PolarHBondContact OD1-OE2 3.43Å; F104-E164 HydrophobicContact CE2-CG 4.43Å; F104-E164 WeakPolarHBondContact CE2-OE1 3.39Å; F104-E164 VanDerWaalsContact CZ-OE2 3.27Å; F104-E164 WeakPolarHBondContact CZ-OE2 3.24Å; Y108-E164 HydrophobicContact CD2-CB 4.38Å; W135-E164 HydrophobicContact CD2-CG 4.24Å; W135-E164 HydrophobicContact CE3-CG 4.27Å; W135-E164 HydrophobicContact CG-CG 4.39Å; V160-E164 HydrophobicContact CG1-CG 4.24Å; V160-E164 WeakPolarHBondContact O-CG 3.19Å; V160-E164 PolarHBondContact O-N 3.2Å; E164-S166 PolarHBondContact O-N 3.13Å; E164-Y167 PolarHBondContact O-N 3.09Å; E164-Y167 VanDerWaalsContact O-N 3.11Å; E164-S168 PolarHBondContact O-N 3.08Å; E164-S168 PolarHBondContact O-OG 3.32Å
165	A	92.6	Very high	92.8	Very high	0 Å²	0	17 Å²	17	0%	0	10%	0.099	C	C	.	.	H	α-helix	trans	-54.4	-38	175.8	0	0	0	0	0	112	Y108 L111 A112 F115 G161 V162 G163 Y167 T169	Y108-A165 HydrophobicContact CD2-CB 3.83Å; Y108-A165 HydrophobicContact CE2-CB 4.23Å; Y108-A165 HydrophobicContact CG-CB 4.4Å; L111-A165 HydrophobicContact CB-CB 4.32Å; A112-A165 HydrophobicContact CB-CB 4.43Å; F115-A165 HydrophobicContact CD2-CB 3.94Å; F115-A165 HydrophobicContact CE2-CB 4.4Å; G161-A165 WeakPolarHBondContact O-CB 3.39Å; G161-A165 PolarHBondContact O-N 3.42Å; V162-A165 WeakPolarHBondContact O-CB 3.29Å; V162-A165 PolarHBondContact O-N 3.23Å; G163-A165 VanDerWaalsContact C-N 3.3Å; G163-A165 PolarHBondContact O-N 3.13Å; A165-Y167 VanDerWaalsContact C-N 3.34Å; A165-Y167 PolarHBondContact O-N 3.37Å; A165-T169 VanDerWaalsContact O-CG2 3.29Å; A165-T169 WeakPolarHBondContact O-CG2 3.2Å; A165-T169 PolarHBondContact O-N 3.45Å; A165-T169 PolarHBondContact O-OG1 3.45Å
166	S	93.1	Very high	92	Very high	0 Å²	0	13.1 Å²	13.1	0%	0	8%	0.082	C	C	.	.	H	α-helix	trans	-60.5	-41.7	179.2	73.3	0	0	0	0	113.3	F115 G131 G163 E164 T169 I170	F115-S166 VanDerWaalsContact CD1-CB 3.41Å; G131-S166 VanDerWaalsContact CA-OG 3.32Å; G131-S166 WeakPolarHBondContact CA-OG 3.32Å; G163-S166 WeakPolarHBondContact O-CB 3.3Å; G163-S166 PolarHBondContact O-N 3.5Å; G163-S166 PolarHBondContact O-OG 3.16Å; E164-S166 PolarHBondContact O-N 3.13Å; S166-T169 PolarHBondContact O-OG1 2.91Å; S166-I170 VanDerWaalsContact O-CB 3.28Å; S166-I170 WeakPolarHBondContact O-CB 3.46Å; S166-I170 VanDerWaalsContact O-CD1 3.27Å; S166-I170 WeakPolarHBondContact O-CD1 3.22Å; S166-I170 WeakPolarHBondContact O-CG1 3.45Å; S166-I170 PolarHBondContact O-N 3.33Å
167	Y	93.6	Very high	91.4	Very high	0 Å²	0	12.9 Å²	12.9	0%	0	8%	0.08	C	C	.	.	H	α-helix	trans	-75.8	-50.7	-175.6	175.7	-100	0	0	0	111.2	L65 I68 N69 M128 W135 E164 A165 T169 I170 A171 F191	L65-Y167 VanDerWaalsContact CA-OH 3.25Å; L65-Y167 WeakPolarHBondContact CA-OH 3.37Å; L65-Y167 HydrophobicContact CD2-CE2 4.03Å; L65-Y167 PolarHBondContact O-OH 2.78Å; I68-Y167 HydrophobicContact CB-CE1 4.26Å; I68-Y167 HydrophobicContact CB-CE2 3.79Å; I68-Y167 HydrophobicContact CD1-CE2 4.14Å; I68-Y167 HydrophobicContact CG2-CD1 4.05Å; I68-Y167 HydrophobicContact CG2-CD2 3.65Å; I68-Y167 HydrophobicContact CG2-CE1 3.78Å; I68-Y167 HydrophobicContact CG2-CE2 3.36Å; I68-Y167 HydrophobicContact CG2-CG 3.99Å; I68-Y167 VanDerWaalsContact CG2-CZ 3.43Å; N69-Y167 HydrophobicContact CB-CE1 4Å; M128-Y167 HydrophobicContact CB-CD2 4.5Å; M128-Y167 HydrophobicContact CG-CD2 4.21Å; M128-Y167 HydrophobicContact SD-CD2 3.89Å; M128-Y167 HydrophobicContact SD-CE2 4.04Å; W135-Y167 HydrophobicContact CH2-CG 4.05Å; W135-Y167 HydrophobicContact CZ3-CG 4.46Å; E164-Y167 PolarHBondContact O-N 3.09Å; E164-Y167 VanDerWaalsContact O-N 3.11Å; A165-Y167 VanDerWaalsContact C-N 3.34Å; A165-Y167 PolarHBondContact O-N 3.37Å; Y167-T169 PolarHBondContact O-N 2.99Å; Y167-I170 PolarHBondContact O-N 3.34Å; Y167-I170 VanDerWaalsContact O-N 3.15Å; Y167-A171 HydrophobicContact CD2-CB 4.22Å; Y167-A171 HydrophobicContact CE1-CB 4.2Å; Y167-A171 HydrophobicContact CE2-CB 3.69Å; Y167-A171 WeakPolarHBondContact O-CB 3.39Å; Y167-A171 PolarHBondContact O-N 2.73Å; Y167-F191 HydrophobicContact CE1-CE2 4.27Å; Y167-F191 HydrophobicContact CE1-CZ 4.23Å; Y167-F191 WeakPolarHBondContact OH-CE2 3.36Å
168	S	89.8	Confident	90.8	Very high	19 Å²	19	12.6 Å²	12.6	13%	0.133	8%	0.079	C	C	.	.	H	α-helix	trans	-65.4	-26.3	-173.7	-57.4	0	0	0	0	113.1	Y108 E164 P172	Y108-S168 WeakPolarHBondContact OH-CB 3.15Å; E164-S168 PolarHBondContact O-N 3.08Å; E164-S168 PolarHBondContact O-OG 3.32Å; S168-P172 WeakPolarHBondContact O-CD 3.41Å
169	T	87	Confident	90.2	Very high	34 Å²	34	12.4 Å²	12.4	21%	0.209	8%	0.076	C	C	.	.	H	α-helix	trans	-82.9	-34.6	174.5	59.2	0	0	0	0	113.2	A112 A165 S166 Y167	A112-T169 HydrophobicContact CB-CG2 3.56Å; A165-T169 VanDerWaalsContact O-CG2 3.29Å; A165-T169 WeakPolarHBondContact O-CG2 3.2Å; A165-T169 PolarHBondContact O-N 3.45Å; A165-T169 PolarHBondContact O-OG1 3.45Å; S166-T169 PolarHBondContact O-OG1 2.91Å; Y167-T169 PolarHBondContact O-N 2.99Å
170	I	90.3	Very high	89.3	Confident	2 Å²	2	10.5 Å²	10.5	1%	0.01	7%	0.067	C	C	.	.	H	α-helix	trans	-89.2	-41	-170.4	-66.1	175.6	0	0	0	111.7	R124 L127 M128 S166 Y167 T173 L174	R124-I170 HydrophobicContact CB-CG2 3.42Å; R124-I170 VanDerWaalsContact CB-CG2 3.42Å; R124-I170 HydrophobicContact CG-CG2 3.53Å; L127-I170 HydrophobicContact CB-CD1 3.69Å; L127-I170 HydrophobicContact CD1-CD1 3.81Å; L127-I170 HydrophobicContact CG-CD1 4.42Å; M128-I170 HydrophobicContact CE-CG2 4.3Å; M128-I170 HydrophobicContact CG-CB 4.09Å; M128-I170 HydrophobicContact CG-CG2 3.87Å; M128-I170 HydrophobicContact SD-CB 4.34Å; M128-I170 HydrophobicContact SD-CG2 3.94Å; S166-I170 VanDerWaalsContact O-CB 3.28Å; S166-I170 WeakPolarHBondContact O-CB 3.46Å; S166-I170 VanDerWaalsContact O-CD1 3.27Å; S166-I170 WeakPolarHBondContact O-CD1 3.22Å; S166-I170 WeakPolarHBondContact O-CG1 3.45Å; S166-I170 PolarHBondContact O-N 3.33Å; Y167-I170 PolarHBondContact O-N 3.34Å; Y167-I170 VanDerWaalsContact O-N 3.15Å; I170-T173 WeakPolarHBondContact O-CB 3.35Å; I170-T173 PolarHBondContact O-N 3.14Å; I170-T173 VanDerWaalsContact O-N 3.09Å; I170-T173 PolarHBondContact O-OG1 2.94Å; I170-L174 PolarHBondContact O-N 3.26Å
171	A	92	Very high	88.4	Confident	0 Å²	0	12.6 Å²	12.6	0%	0	8%	0.084	C	C	.	.	H	α-helix	trans	-57.8	-43.6	-172.6	0	0	0	0	0	114.2	L65 M128 Y167 T173 L174 I175 F191	L65-A171 HydrophobicContact CD2-CB 4.22Å; M128-A171 HydrophobicContact SD-CB 4.17Å; Y167-A171 HydrophobicContact CD2-CB 4.22Å; Y167-A171 HydrophobicContact CE1-CB 4.2Å; Y167-A171 HydrophobicContact CE2-CB 3.69Å; Y167-A171 WeakPolarHBondContact O-CB 3.39Å; Y167-A171 PolarHBondContact O-N 2.73Å; A171-T173 VanDerWaalsContact C-N 3.28Å; A171-T173 PolarHBondContact O-N 3.3Å; A171-L174 WeakPolarHBondContact O-CB 3.23Å; A171-L174 PolarHBondContact O-N 2.93Å; A171-L174 VanDerWaalsContact O-N 3.16Å; A171-I175 WeakPolarHBondContact O-CG1 3.44Å; A171-I175 PolarHBondContact O-N 2.89Å; A171-I175 VanDerWaalsContact O-N 3.13Å; A171-F191 HydrophobicContact CB-CE2 3.92Å; A171-F191 HydrophobicContact CB-CZ 3.92Å
172	P	88.4	Confident	87.4	Confident	21 Å²	21	19.4 Å²	19.4	14%	0.136	12%	0.12	C	C	.	.	H	α-helix	trans	-61.1	-35.4	176.6	-24.2	35.3	0	0	0	113.2	S168 L174 I175 A176 L188 F191	S168-P172 WeakPolarHBondContact O-CD 3.41Å; P172-L174 VanDerWaalsContact C-N 3.33Å; P172-L174 PolarHBondContact O-N 3.05Å; P172-I175 PolarHBondContact O-N 3.34Å; P172-A176 WeakPolarHBondContact O-CB 3.45Å; P172-A176 PolarHBondContact O-N 2.89Å; P172-L188 HydrophobicContact CB-CD2 4.09Å; P172-F191 HydrophobicContact CG-CE1 3.93Å; P172-F191 HydrophobicContact CG-CZ 4.35Å
173	T	85.9	Confident	86.6	Confident	50 Å²	50	20.3 Å²	20.3	31%	0.307	12%	0.122	S	C	.	.	H	α-helix	trans	-67.7	-35.2	177.8	75.8	0	0	0	0	111.8	R124 I170 A171 A176 D177	R124-T173 PolarHBondContact NH1-O 3.39Å; R124-T173 PolarHBondContact NH1-OG1 3.37Å; I170-T173 WeakPolarHBondContact O-CB 3.35Å; I170-T173 PolarHBondContact O-N 3.14Å; I170-T173 VanDerWaalsContact O-N 3.09Å; I170-T173 PolarHBondContact O-OG1 2.94Å; A171-T173 VanDerWaalsContact C-N 3.28Å; A171-T173 PolarHBondContact O-N 3.3Å; T173-A176 PolarHBondContact O-N 3.05Å; T173-D177 PolarHBondContact O-N 2.93Å; T173-D177 VanDerWaalsContact O-N 3.13Å
174	L	88.4	Confident	85.9	Confident	0 Å²	0	23.9 Å²	23.9	0%	0	14%	0.135	C	C	.	.	H	α-helix	trans	-67.1	-41.6	176.2	-175.8	66.9	0	0	0	110.7	I61 L65 M128 I170 A171 P172 A176 D177 L178 V238 P241	I61-L174 HydrophobicContact CG2-CD2 4.37Å; L65-L174 HydrophobicContact CD1-CD2 4Å; L65-L174 HydrophobicContact CD1-CG 4.47Å; L65-L174 HydrophobicContact CD2-CD2 4.36Å; M128-L174 HydrophobicContact CE-CD2 3.69Å; I170-L174 PolarHBondContact O-N 3.26Å; A171-L174 WeakPolarHBondContact O-CB 3.23Å; A171-L174 PolarHBondContact O-N 2.93Å; A171-L174 VanDerWaalsContact O-N 3.16Å; P172-L174 VanDerWaalsContact C-N 3.33Å; P172-L174 PolarHBondContact O-N 3.05Å; L174-A176 VanDerWaalsContact C-N 3.31Å; L174-A176 PolarHBondContact O-N 3.16Å; L174-D177 PolarHBondContact O-N 3.43Å; L174-L178 VanDerWaalsContact O-CG 3.31Å; L174-L178 WeakPolarHBondContact O-CG 3.44Å; L174-L178 PolarHBondContact O-N 2.71Å; L174-V238 HydrophobicContact CD2-CG1 3.69Å; L174-P241 HydrophobicContact CD1-CG 3.66Å
175	I	87.8	Confident	84.9	Confident	0 Å²	0	27.1 Å²	27.1	0%	0	16%	0.158	C	C	.	.	H	α-helix	trans	-63	-40.6	174.1	-61.4	172.1	0	0	0	110.5	V62 L65 A171 P172 D177 L178 F179 M187 L188 F191	V62-I175 HydrophobicContact CG2-CG1 4.34Å; V62-I175 HydrophobicContact CG2-CG2 4.4Å; L65-I175 HydrophobicContact CD1-CD1 4.07Å; L65-I175 HydrophobicContact CD1-CG1 3.59Å; A171-I175 WeakPolarHBondContact O-CG1 3.44Å; A171-I175 PolarHBondContact O-N 2.89Å; A171-I175 VanDerWaalsContact O-N 3.13Å; P172-I175 PolarHBondContact O-N 3.34Å; I175-D177 VanDerWaalsContact C-N 3.27Å; I175-D177 PolarHBondContact O-N 3.34Å; I175-L178 PolarHBondContact O-N 2.89Å; I175-L178 VanDerWaalsContact O-N 3.13Å; I175-F179 HydrophobicContact CG2-CD2 4.29Å; I175-F179 PolarHBondContact O-N 3.45Å; I175-M187 HydrophobicContact CG2-CB 3.79Å; I175-L188 HydrophobicContact CB-CD2 3.96Å; I175-L188 HydrophobicContact CD1-CD2 4.28Å; I175-L188 HydrophobicContact CG2-CD2 3.85Å; I175-L188 HydrophobicContact CG2-CG 4.02Å; I175-F191 HydrophobicContact CD1-CB 3.76Å; I175-F191 HydrophobicContact CD1-CD2 3.62Å; I175-F191 HydrophobicContact CD1-CE2 4.33Å; I175-F191 HydrophobicContact CD1-CG 3.72Å
176	A	81.5	Confident	84.4	Confident	19 Å²	19	33.6 Å²	33.6	16%	0.157	18%	0.182	C	C	.	.	H	α-helix	trans	-63.1	-31.4	179	0	0	0	0	0	113.5	P172 T173 L174	P172-A176 WeakPolarHBondContact O-CB 3.45Å; P172-A176 PolarHBondContact O-N 2.89Å; T173-A176 PolarHBondContact O-N 3.05Å; L174-A176 VanDerWaalsContact C-N 3.31Å; L174-A176 PolarHBondContact O-N 3.16Å
177	D	83	Confident	84.2	Confident	12 Å²	12	34.5 Å²	34.5	6%	0.064	19%	0.187	C	C	.	.	H	α-helix	trans	-81.4	-13.6	175.9	-80.2	-26.1	0	0	0	113.9	R124 T173 L174 I175 P241 G244 V246	R124-D177 IonicContact CZ-OD2 2.58Å; R124-D177 IonicContact NH1-OD2 3.38Å; R124-D177 PolarHBondContact NH1-OD2 2.98Å; R124-D177 IonicContact NH2-OD2 3.31Å; R124-D177 PolarHBondContact NH2-OD2 2.9Å; T173-D177 PolarHBondContact O-N 2.93Å; T173-D177 VanDerWaalsContact O-N 3.13Å; L174-D177 PolarHBondContact O-N 3.43Å; I175-D177 VanDerWaalsContact C-N 3.27Å; I175-D177 PolarHBondContact O-N 3.34Å; D177-P241 HydrophobicContact CB-CG 3.96Å; D177-G244 WeakPolarHBondContact OD1-CA 3.4Å; D177-G244 PolarHBondContact OD1-N 3.38Å; D177-V246 VanDerWaalsContact O-CG2 3.23Å; D177-V246 WeakPolarHBondContact O-CG2 3.42Å
178	L	84.9	Confident	83.6	Confident	1 Å²	1	36.2 Å²	36.2	1%	0.005	20%	0.196	C	C	.	.	H	α-helix	trans	-92.3	-21.2	-178.9	-72	170.7	0	0	0	113.6	L47 L53 I61 L174 I175 P241	L47-L178 WeakPolarHBondContact CD2-O 3.25Å; L53-L178 HydrophobicContact CD1-CD2 3.63Å; I61-L178 HydrophobicContact CB-CD1 4.09Å; I61-L178 HydrophobicContact CD1-CD1 4.32Å; I61-L178 HydrophobicContact CD1-CD2 4.41Å; I61-L178 HydrophobicContact CG2-CD1 3.6Å; L174-L178 VanDerWaalsContact O-CG 3.31Å; L174-L178 WeakPolarHBondContact O-CG 3.44Å; L174-L178 PolarHBondContact O-N 2.71Å; I175-L178 PolarHBondContact O-N 2.89Å; I175-L178 VanDerWaalsContact O-N 3.13Å; L178-P241 HydrophobicContact CD2-CB 4.05Å; L178-P241 HydrophobicContact CD2-CG 3.99Å; L178-P241 HydrophobicContact CG-CG 4.29Å
179	F	83.4	Confident	83.2	Confident	5 Å²	5	39 Å²	39	2%	0.022	22%	0.216	C	C	.	.			trans	-137.8	150.1	-172.4	-59.7	-85.1	0	0	0	112.1	V62 I175 Q183 R184 M187	V62-F179 HydrophobicContact CG2-CD2 4.39Å; V62-F179 HydrophobicContact CG2-CE2 3.4Å; V62-F179 HydrophobicContact CG2-CZ 3.94Å; I175-F179 HydrophobicContact CG2-CD2 4.29Å; I175-F179 PolarHBondContact O-N 3.45Å; F179-Q183 HydrophobicContact CB-CB 4.22Å; F179-Q183 HydrophobicContact CD1-CB 4.13Å; F179-R184 HydrophobicContact CB-CB 4.04Å; F179-R184 WeakPolarHBondContact O-CB 3.3Å; F179-M187 HydrophobicContact CD1-CG 4.2Å; F179-M187 HydrophobicContact CD2-CB 4.17Å; F179-M187 HydrophobicContact CD2-CG 3.87Å; F179-M187 HydrophobicContact CE1-CE 4.24Å; F179-M187 HydrophobicContact CE1-CG 4.1Å; F179-M187 HydrophobicContact CE2-CB 4.3Å; F179-M187 HydrophobicContact CE2-CG 3.8Å; F179-M187 HydrophobicContact CG-CG 4.08Å; F179-M187 HydrophobicContact CZ-CE 4.4Å; F179-M187 HydrophobicContact CZ-CG 3.9Å; F179-M187 HydrophobicContact CZ-SD 4.42Å
180	V	79	Confident	83.3	Confident	23 Å²	23	41 Å²	41	14%	0.139	23%	0.228	C	C	.	.			trans	-104.6	156.2	173.9	-74.9	0	0	0	0	112.4	I41 P42 L47 D182 Q183 R184 V246	I41-V180 HydrophobicContact CG2-CB 4.16Å; I41-V180 HydrophobicContact CG2-CG2 3.88Å; P42-V180 HydrophobicContact CG-CG1 4.09Å; L47-V180 HydrophobicContact CD1-CB 4.34Å; L47-V180 HydrophobicContact CD1-CG1 3.86Å; L47-V180 HydrophobicContact CD1-CG2 3.53Å; L47-V180 HydrophobicContact CD2-CG2 4.48Å; V180-D182 PolarHBondContact O-N 3.48Å; V180-Q183 PolarHBondContact O-N 3.46Å; V180-Q183 VanDerWaalsContact O-N 3.13Å; V180-R184 PolarHBondContact O-N 2.72Å; V180-V246 HydrophobicContact CB-CG1 4.33Å; V180-V246 HydrophobicContact CG1-CB 4.47Å; V180-V246 HydrophobicContact CG1-CG1 3.08Å
181	A	76.6	Confident	83.2	Confident	45 Å²	45	41.1 Å²	41.1	37%	0.372	23%	0.228	S	C	.	.	H	α-helix	trans	47.4	-129.4	164.5	0	0	0	0	0	113.3	I41 Q183 R184 S185	I41-A181 HydrophobicContact CD1-CB 4.27Å; I41-A181 HydrophobicContact CG2-CB 4.48Å; A181-Q183 VanDerWaalsContact C-N 3.25Å; A181-Q183 PolarHBondContact O-N 3.19Å; A181-R184 WeakPolarHBondContact O-CB 3.46Å; A181-R184 PolarHBondContact O-N 3.35Å; A181-R184 VanDerWaalsContact O-N 3.14Å; A181-S185 PolarHBondContact O-N 3.4Å
182	D	74.3	Confident	82.9	Confident	142 Å²	142	46.6 Å²	46.6	76%	0.759	25%	0.25	S	C	*	.	H	α-helix	trans	-61.9	-30.1	-176.4	-66.3	-23.8	0	0	0	113.4	V180 R186	V180-D182 PolarHBondContact O-N 3.48Å; D182-R186 WeakPolarHBondContact O-CB 3.41Å; D182-R186 PolarHBondContact O-N 3.22Å
183	Q	77.8	Confident	82.7	Confident	52 Å²	52	50.9 Å²	50.9	24%	0.243	27%	0.266	C	S	.	.	H	α-helix	trans	-68.9	-37.7	177.3	-67.4	-155.5	32.8	0	0	111.7	F179 V180 A181 R186 M187	F179-Q183 HydrophobicContact CB-CB 4.22Å; F179-Q183 HydrophobicContact CD1-CB 4.13Å; V180-Q183 PolarHBondContact O-N 3.46Å; V180-Q183 VanDerWaalsContact O-N 3.13Å; A181-Q183 VanDerWaalsContact C-N 3.25Å; A181-Q183 PolarHBondContact O-N 3.19Å; Q183-R186 PolarHBondContact O-N 3.46Å; Q183-M187 VanDerWaalsContact O-CG 3.3Å; Q183-M187 WeakPolarHBondContact O-CG 3.38Å; Q183-M187 PolarHBondContact O-N 2.94Å
184	R	81	Confident	82.9	Confident	76 Å²	76	49 Å²	49	29%	0.287	26%	0.256	S	S	.	.	H	α-helix	trans	-59.8	-51.9	175.3	-176.3	172.2	66.5	173.2	4.1	110.9	F179 V180 A181 R186 M187 L188 E247	F179-R184 HydrophobicContact CB-CB 4.04Å; F179-R184 WeakPolarHBondContact O-CB 3.3Å; V180-R184 PolarHBondContact O-N 2.72Å; A181-R184 WeakPolarHBondContact O-CB 3.46Å; A181-R184 PolarHBondContact O-N 3.35Å; A181-R184 VanDerWaalsContact O-N 3.14Å; R184-R186 VanDerWaalsContact C-N 3.3Å; R184-R186 PolarHBondContact O-N 3.36Å; R184-M187 PolarHBondContact O-N 3.35Å; R184-L188 HydrophobicContact CG-CD1 4.01Å; R184-L188 WeakPolarHBondContact O-CB 3.48Å; R184-L188 WeakPolarHBondContact O-CG 3.45Å; R184-L188 PolarHBondContact O-N 2.65Å; R184-E247 IonicContact NH1-OE1 3.29Å; R184-E247 PolarHBondContact NH1-OE1 3.32Å
185	S	73.3	Confident	82.9	Confident	68 Å²	68	51.1 Å²	51.1	48%	0.476	27%	0.267	S	S	.	.	H	α-helix	trans	-58.1	-44.1	178	-57	0	0	0	0	111.3	A181 M187 L188 S189	A181-S185 PolarHBondContact O-N 3.4Å; S185-M187 PolarHBondContact O-N 3.3Å; S185-L188 PolarHBondContact O-N 2.98Å; S185-S189 PolarHBondContact O-N 2.89Å; S185-S189 PolarHBondContact O-OG 3.13Å
186	R	82.1	Confident	82.9	Confident	136 Å²	136	52.3 Å²	52.3	51%	0.513	28%	0.275	S	S	.	.	H	α-helix	trans	-61.9	-44.3	177.5	-173.2	177.7	65.6	-174.5	-0.2	112.8	D182 Q183 R184 S189 V190	D182-R186 WeakPolarHBondContact O-CB 3.41Å; D182-R186 PolarHBondContact O-N 3.22Å; Q183-R186 PolarHBondContact O-N 3.46Å; R184-R186 VanDerWaalsContact C-N 3.3Å; R184-R186 PolarHBondContact O-N 3.36Å; R186-S189 PolarHBondContact O-N 3.14Å; R186-V190 WeakPolarHBondContact O-CG2 3.39Å; R186-V190 PolarHBondContact O-N 3.11Å; R186-V190 VanDerWaalsContact O-N 3.07Å
187	M	87.3	Confident	83.3	Confident	19 Å²	19	53.3 Å²	53.3	9%	0.094	28%	0.278	C	S	.	.	H	α-helix	trans	-69.6	-38.3	-179.6	-67.3	-58.3	165.1	0	0	112.1	V62 I175 F179 Q183 R184 S185 S189 V190 F191	V62-M187 HydrophobicContact CB-SD 4.49Å; V62-M187 HydrophobicContact CG1-CB 4.35Å; V62-M187 HydrophobicContact CG1-SD 4.09Å; V62-M187 HydrophobicContact CG2-CB 4.26Å; V62-M187 HydrophobicContact CG2-CG 4.35Å; V62-M187 HydrophobicContact CG2-SD 4.38Å; I175-M187 HydrophobicContact CG2-CB 3.79Å; F179-M187 HydrophobicContact CD1-CG 4.2Å; F179-M187 HydrophobicContact CD2-CB 4.17Å; F179-M187 HydrophobicContact CD2-CG 3.87Å; F179-M187 HydrophobicContact CE1-CE 4.24Å; F179-M187 HydrophobicContact CE1-CG 4.1Å; F179-M187 HydrophobicContact CE2-CB 4.3Å; F179-M187 HydrophobicContact CE2-CG 3.8Å; F179-M187 HydrophobicContact CG-CG 4.08Å; F179-M187 HydrophobicContact CZ-CE 4.4Å; F179-M187 HydrophobicContact CZ-CG 3.9Å; F179-M187 HydrophobicContact CZ-SD 4.42Å; Q183-M187 VanDerWaalsContact O-CG 3.3Å; Q183-M187 WeakPolarHBondContact O-CG 3.38Å; Q183-M187 PolarHBondContact O-N 2.94Å; R184-M187 PolarHBondContact O-N 3.35Å; S185-M187 PolarHBondContact O-N 3.3Å; M187-S189 VanDerWaalsContact C-N 3.34Å; M187-V190 PolarHBondContact O-N 2.96Å; M187-F191 PolarHBondContact O-N 3.14Å
188	L	82.5	Confident	83.9	Confident	36 Å²	36	52.7 Å²	52.7	19%	0.188	28%	0.275	C	S	.	.	H	α-helix	trans	-63.3	-39.3	171.8	-71.6	172.3	0	0	0	111.8	P172 I175 R184 S185 V190 F191 Y192	P172-L188 HydrophobicContact CB-CD2 4.09Å; I175-L188 HydrophobicContact CB-CD2 3.96Å; I175-L188 HydrophobicContact CD1-CD2 4.28Å; I175-L188 HydrophobicContact CG2-CD2 3.85Å; I175-L188 HydrophobicContact CG2-CG 4.02Å; R184-L188 HydrophobicContact CG-CD1 4.01Å; R184-L188 WeakPolarHBondContact O-CB 3.48Å; R184-L188 WeakPolarHBondContact O-CG 3.45Å; R184-L188 PolarHBondContact O-N 2.65Å; S185-L188 PolarHBondContact O-N 2.98Å; L188-V190 PolarHBondContact O-N 3.13Å; L188-F191 WeakPolarHBondContact O-CB 3.43Å; L188-F191 PolarHBondContact O-N 3.33Å; L188-Y192 HydrophobicContact CB-CD2 4.47Å; L188-Y192 HydrophobicContact CB-CE2 4.31Å; L188-Y192 WeakPolarHBondContact O-CD2 3.3Å; L188-Y192 PolarHBondContact O-N 2.9Å
189	S	80.9	Confident	84.2	Confident	78 Å²	78	53.1 Å²	53.1	55%	0.545	28%	0.278	S	S	.	.	H	α-helix	trans	-61.4	-41.9	173.8	-63.1	0	0	0	0	112.3	S185 R186 M187 F191 Y192 F193	S185-S189 PolarHBondContact O-N 2.89Å; S185-S189 PolarHBondContact O-OG 3.13Å; R186-S189 PolarHBondContact O-N 3.14Å; M187-S189 VanDerWaalsContact C-N 3.34Å; S189-F191 VanDerWaalsContact C-N 3.33Å; S189-Y192 PolarHBondContact O-N 3.03Å; S189-F193 WeakPolarHBondContact O-CB 3.28Å; S189-F193 PolarHBondContact O-N 3.26Å
190	V	88.1	Confident	84.7	Confident	77 Å²	77	52.9 Å²	52.9	47%	0.467	28%	0.277	S	S	.	.	H	α-helix	trans	-63	-42	175	175.7	0	0	0	0	110.9	R186 M187 L188 F193	R186-V190 WeakPolarHBondContact O-CG2 3.39Å; R186-V190 PolarHBondContact O-N 3.11Å; R186-V190 VanDerWaalsContact O-N 3.07Å; M187-V190 PolarHBondContact O-N 2.96Å; L188-V190 PolarHBondContact O-N 3.13Å; V190-F193 PolarHBondContact O-N 2.99Å
191	F	89.7	Confident	85.4	Confident	4 Å²	4	54.8 Å²	54.8	2%	0.018	29%	0.286	C	S	.	.	H	α-helix	trans	-60	-48.5	176.4	175.9	-94.5	0	0	0	112.4	L65 C66 N69 Y167 A171 P172 I175 M187 L188 S189 F193 A194	L65-F191 HydrophobicContact CB-CD2 4.28Å; L65-F191 HydrophobicContact CB-CE2 4.28Å; C66-F191 VanDerWaalsContact SG-CA 3.6Å; N69-F191 HydrophobicContact CB-CD2 4.11Å; N69-F191 HydrophobicContact CB-CE2 3.62Å; N69-F191 HydrophobicContact CB-CZ 3.94Å; N69-F191 PolarHBondContact ND2-O 3.13Å; Y167-F191 HydrophobicContact CE1-CE2 4.27Å; Y167-F191 HydrophobicContact CE1-CZ 4.23Å; Y167-F191 WeakPolarHBondContact OH-CE2 3.36Å; A171-F191 HydrophobicContact CB-CE2 3.92Å; A171-F191 HydrophobicContact CB-CZ 3.92Å; P172-F191 HydrophobicContact CG-CE1 3.93Å; P172-F191 HydrophobicContact CG-CZ 4.35Å; I175-F191 HydrophobicContact CD1-CB 3.76Å; I175-F191 HydrophobicContact CD1-CD2 3.62Å; I175-F191 HydrophobicContact CD1-CE2 4.33Å; I175-F191 HydrophobicContact CD1-CG 3.72Å; M187-F191 PolarHBondContact O-N 3.14Å; L188-F191 WeakPolarHBondContact O-CB 3.43Å; L188-F191 PolarHBondContact O-N 3.33Å; S189-F191 VanDerWaalsContact C-N 3.33Å; F191-F193 VanDerWaalsContact C-N 3.33Å; F191-F193 PolarHBondContact O-N 3.45Å; F191-A194 VanDerWaalsContact O-CB 3.28Å; F191-A194 WeakPolarHBondContact O-CB 3.33Å; F191-A194 PolarHBondContact O-N 3.25Å
192	Y	85.1	Confident	86.3	Confident	115 Å²	115	52.7 Å²	52.7	45%	0.451	27%	0.269	S	S	.	.	H	α-helix	trans	-73.6	-22.8	179.8	-67.9	-53.4	0	0	0	113.5	L188 S189 A194 I195	L188-Y192 HydrophobicContact CB-CD2 4.47Å; L188-Y192 HydrophobicContact CB-CE2 4.31Å; L188-Y192 WeakPolarHBondContact O-CD2 3.3Å; L188-Y192 PolarHBondContact O-N 2.9Å; S189-Y192 PolarHBondContact O-N 3.03Å; Y192-A194 PolarHBondContact O-N 3.24Å; Y192-I195 HydrophobicContact CD1-CD1 3.8Å; Y192-I195 VanDerWaalsContact O-CB 3.25Å; Y192-I195 WeakPolarHBondContact O-CB 3.37Å; Y192-I195 VanDerWaalsContact O-CG1 3.24Å; Y192-I195 WeakPolarHBondContact O-CG1 3.42Å; Y192-I195 PolarHBondContact O-N 2.86Å
193	F	84.8	Confident	87.2	Confident	110 Å²	110	46 Å²	46	48%	0.482	23%	0.233	S	C	.	.	H	α-helix	trans	-63.5	-22.3	172	-165.2	-97.9	0	0	0	112.8	S189 V190 F191 I195 P196 V197 V334	S189-F193 WeakPolarHBondContact O-CB 3.28Å; S189-F193 PolarHBondContact O-N 3.26Å; V190-F193 PolarHBondContact O-N 2.99Å; F191-F193 VanDerWaalsContact C-N 3.33Å; F191-F193 PolarHBondContact O-N 3.45Å; F193-I195 PolarHBondContact O-N 3.3Å; F193-P196 VanDerWaalsContact O-CD 3.31Å; F193-P196 WeakPolarHBondContact O-CD 3.25Å; F193-P196 WeakPolarHBondContact O-CG 3.26Å; F193-V197 HydrophobicContact CD1-CG2 4.23Å; F193-V197 HydrophobicContact CE1-CG2 4.04Å; F193-V334 HydrophobicContact CE1-CG2 3.99Å; F193-V334 HydrophobicContact CE2-CB 4.17Å; F193-V334 HydrophobicContact CE2-CG1 3.81Å; F193-V334 HydrophobicContact CE2-CG2 3.67Å; F193-V334 HydrophobicContact CZ-CB 4Å; F193-V334 HydrophobicContact CZ-CG1 3.57Å; F193-V334 HydrophobicContact CZ-CG2 3.27Å
194	A	88.8	Confident	88	Confident	11 Å²	11	45.3 Å²	45.3	9%	0.091	23%	0.231	C	C	.	.	H	α-helix	trans	-66.4	-18	173.7	0	0	0	0	0	113.3	N69 L70 F191 Y192 G198	N69-A194 HydrophobicContact CB-CB 4.24Å; L70-A194 HydrophobicContact CB-CB 4.3Å; F191-A194 VanDerWaalsContact O-CB 3.28Å; F191-A194 WeakPolarHBondContact O-CB 3.33Å; F191-A194 PolarHBondContact O-N 3.25Å; Y192-A194 PolarHBondContact O-N 3.24Å; A194-G198 WeakPolarHBondContact O-CA 3.29Å; A194-G198 PolarHBondContact O-N 3.45Å
195	I	88.9	Confident	88.6	Confident	45 Å²	45	42.7 Å²	42.7	23%	0.231	23%	0.225	C	C	.	.	H	α-helix	trans	-61.6	-62.3	-179.3	-63	-179.4	0	0	0	112.3	Y73 Y192 F193 V197 G198 S199	Y73-I195 HydrophobicContact CD1-CB 4.43Å; Y73-I195 HydrophobicContact CD1-CG2 3.79Å; Y73-I195 HydrophobicContact CD2-CB 4.41Å; Y73-I195 HydrophobicContact CD2-CG1 3.99Å; Y73-I195 HydrophobicContact CE1-CB 4.23Å; Y73-I195 HydrophobicContact CE1-CG1 4.2Å; Y73-I195 HydrophobicContact CE1-CG2 3.44Å; Y73-I195 VanDerWaalsContact CE1-CG2 3.44Å; Y73-I195 HydrophobicContact CE2-CB 4.24Å; Y73-I195 HydrophobicContact CE2-CD1 4.06Å; Y73-I195 HydrophobicContact CE2-CG1 3.49Å; Y73-I195 VanDerWaalsContact CE2-CG1 3.49Å; Y73-I195 HydrophobicContact CE2-CG2 4.32Å; Y73-I195 HydrophobicContact CG-CG2 4.33Å; Y73-I195 WeakPolarHBondContact OH-CD1 3.37Å; Y192-I195 HydrophobicContact CD1-CD1 3.8Å; Y192-I195 VanDerWaalsContact O-CB 3.25Å; Y192-I195 WeakPolarHBondContact O-CB 3.37Å; Y192-I195 VanDerWaalsContact O-CG1 3.24Å; Y192-I195 WeakPolarHBondContact O-CG1 3.42Å; Y192-I195 PolarHBondContact O-N 2.86Å; F193-I195 PolarHBondContact O-N 3.3Å; I195-V197 VanDerWaalsContact C-N 3.31Å; I195-V197 PolarHBondContact O-N 3Å; I195-G198 PolarHBondContact O-N 2.87Å; I195-S199 WeakPolarHBondContact O-CB 3.33Å; I195-S199 PolarHBondContact O-N 3.32Å; I195-S199 PolarHBondContact O-OG 2.86Å
196	P	87.6	Confident	89.4	Confident	25 Å²	25	39.5 Å²	39.5	16%	0.162	20%	0.203	C	C	.	.	H	α-helix	trans	-63.5	-38	-178.8	23.4	-34.6	0	0	0	112.1	F193 S199 G200	F193-P196 VanDerWaalsContact O-CD 3.31Å; F193-P196 WeakPolarHBondContact O-CD 3.25Å; F193-P196 WeakPolarHBondContact O-CG 3.26Å; P196-S199 PolarHBondContact O-N 2.88Å; P196-G200 PolarHBondContact O-N 3.36Å; P196-G200 VanDerWaalsContact O-N 3.09Å
197	V	91	Very high	89.8	Confident	39 Å²	39	33 Å²	33	24%	0.236	18%	0.178	C	C	.	.	H	α-helix	trans	-66.6	-48.3	179.5	-179.4	0	0	0	0	111.3	L70 F193 I195 S199 G200 L201 C330 V334	L70-V197 HydrophobicContact CD1-CG1 4.33Å; F193-V197 HydrophobicContact CD1-CG2 4.23Å; F193-V197 HydrophobicContact CE1-CG2 4.04Å; I195-V197 VanDerWaalsContact C-N 3.31Å; I195-V197 PolarHBondContact O-N 3Å; V197-S199 VanDerWaalsContact C-N 3.28Å; V197-S199 PolarHBondContact O-N 2.86Å; V197-G200 PolarHBondContact O-N 2.82Å; V197-L201 HydrophobicContact CG1-CD1 4.02Å; V197-L201 HydrophobicContact CG1-CG 4.48Å; V197-L201 WeakPolarHBondContact O-CB 3.29Å; V197-L201 VanDerWaalsContact O-CG 3.29Å; V197-L201 WeakPolarHBondContact O-CG 3.45Å; V197-L201 PolarHBondContact O-N 2.82Å; V197-C330 PolarHBondContact O-SG 3.37Å; V197-V334 HydrophobicContact CG2-CG2 4.44Å
198	G	93.9	Very high	90	Very high	0 Å²	0	37.4 Å²	37.4	0%	0	20%	0.197	C	C	.	.	H	α-helix	trans	-61.6	-38.1	176.8	0	0	0	0	0	111.9	M74 A194 I195 L201 G202	M74-G198 VanDerWaalsContact CA-O 3.29Å; M74-G198 WeakPolarHBondContact CA-O 3.19Å; M74-G198 PolarHBondContact N-O 3Å; A194-G198 WeakPolarHBondContact O-CA 3.29Å; A194-G198 PolarHBondContact O-N 3.45Å; I195-G198 PolarHBondContact O-N 2.87Å; G198-L201 PolarHBondContact O-N 3.45Å; G198-G202 PolarHBondContact O-N 3.23Å
199	S	92.6	Very high	90.5	Very high	10 Å²	10	37.3 Å²	37.3	7%	0.07	20%	0.197	C	C	.	.	H	α-helix	trans	-63.3	-48.9	178.1	-54.4	0	0	0	0	112.4	F77 I195 P196 V197 G202 Y203	F77-S199 VanDerWaalsContact CD2-CB 3.45Å; F77-S199 WeakPolarHBondContact CD2-OG 3.32Å; F77-S199 WeakPolarHBondContact CE2-OG 3.21Å; I195-S199 WeakPolarHBondContact O-CB 3.33Å; I195-S199 PolarHBondContact O-N 3.32Å; I195-S199 PolarHBondContact O-OG 2.86Å; P196-S199 PolarHBondContact O-N 2.88Å; V197-S199 VanDerWaalsContact C-N 3.28Å; V197-S199 PolarHBondContact O-N 2.86Å; S199-G202 PolarHBondContact O-N 3.15Å; S199-G202 VanDerWaalsContact O-N 3.13Å; S199-Y203 WeakPolarHBondContact O-CD2 3.35Å; S199-Y203 WeakPolarHBondContact O-CE2 3.27Å; S199-Y203 PolarHBondContact O-N 3.49Å
200	G	93.6	Very high	90.9	Very high	0 Å²	0	33.8 Å²	33.8	0%	0	17%	0.172	C	C	.	.	H	α-helix	trans	-63.9	-40.9	176	0	0	0	0	0	112.9	P196 V197 G202 Y203 I204 G326 C330	P196-G200 PolarHBondContact O-N 3.36Å; P196-G200 VanDerWaalsContact O-N 3.09Å; V197-G200 PolarHBondContact O-N 2.82Å; G200-G202 PolarHBondContact O-N 3.27Å; G200-Y203 PolarHBondContact O-N 2.86Å; G200-I204 WeakPolarHBondContact O-CD1 3.44Å; G200-I204 VanDerWaalsContact O-CG1 3.29Å; G200-I204 WeakPolarHBondContact O-CG1 3.48Å; G200-I204 PolarHBondContact O-N 3.44Å; G200-G326 WeakPolarHBondContact CA-O 3.42Å; G200-C330 VanDerWaalsContact CA-SG 3.52Å
201	L	94.4	Very high	90.9	Very high	63 Å²	63	32.6 Å²	32.6	33%	0.33	16%	0.163	S	C	.	.	H	α-helix	trans	-61.7	-30.3	172.8	-71.9	175.7	0	0	0	112.6	L70 M74 V197 G198 I204 A205	L70-L201 HydrophobicContact CD1-CD1 3.99Å; L70-L201 HydrophobicContact CD2-CD1 3.84Å; L70-L201 HydrophobicContact CG-CD1 4.17Å; M74-L201 HydrophobicContact CG-CB 4.31Å; M74-L201 HydrophobicContact SD-CB 4.17Å; V197-L201 HydrophobicContact CG1-CD1 4.02Å; V197-L201 HydrophobicContact CG1-CG 4.48Å; V197-L201 WeakPolarHBondContact O-CB 3.29Å; V197-L201 VanDerWaalsContact O-CG 3.29Å; V197-L201 WeakPolarHBondContact O-CG 3.45Å; V197-L201 PolarHBondContact O-N 2.82Å; G198-L201 PolarHBondContact O-N 3.45Å; L201-I204 HydrophobicContact CD2-CD1 4.47Å; L201-I204 PolarHBondContact O-N 3.24Å; L201-A205 WeakPolarHBondContact O-CB 3.19Å; L201-A205 PolarHBondContact O-N 2.99Å
202	G	94.4	Very high	90.9	Very high	0 Å²	0	37.9 Å²	37.9	0%	0	20%	0.196	C	C	.	.	H	α-helix	trans	-60.3	-50.5	175	0	0	0	0	0	112.4	M74 T78 G198 S199 G200 I204 A205 G206	M74-G202 VanDerWaalsContact O-CA 3.29Å; M74-G202 WeakPolarHBondContact O-CA 3.45Å; T78-G202 WeakPolarHBondContact CA-O 3.3Å; G198-G202 PolarHBondContact O-N 3.23Å; S199-G202 PolarHBondContact O-N 3.15Å; S199-G202 VanDerWaalsContact O-N 3.13Å; G200-G202 PolarHBondContact O-N 3.27Å; G202-I204 VanDerWaalsContact C-N 3.33Å; G202-I204 PolarHBondContact O-N 3.46Å; G202-A205 PolarHBondContact O-N 3.43Å; G202-G206 PolarHBondContact O-N 3Å
203	Y	94.5	Very high	91.1	Very high	3 Å²	3	34.6 Å²	34.6	1%	0.012	19%	0.193	C	C	.	.	H	α-helix	trans	-62.6	-41.8	176.3	-57.1	-72.5	0	0	0	112.1	F77 A80 S199 G200 S207 A291 P295 S322 F325 T329	F77-Y203 HydrophobicContact CB-CD1 4.39Å; F77-Y203 HydrophobicContact CB-CD2 4.44Å; F77-Y203 HydrophobicContact CB-CE1 4.08Å; F77-Y203 HydrophobicContact CB-CE2 4.14Å; F77-Y203 HydrophobicContact CD1-CE1 4.19Å; F77-Y203 HydrophobicContact CD1-CE2 4.39Å; F77-Y203 AromaticContact CD1-CZ 3.69Å; F77-Y203 WeakPolarHBondContact CD1-OH 3.45Å; F77-Y203 HydrophobicContact CG-CE1 4.48Å; F77-Y203 HydrophobicContact CG-CE2 4.25Å; F77-Y203 AromaticContact CG-CZ 3.95Å; A80-Y203 HydrophobicContact CB-CD1 4.1Å; A80-Y203 HydrophobicContact CB-CE1 3.55Å; S199-Y203 WeakPolarHBondContact O-CD2 3.35Å; S199-Y203 WeakPolarHBondContact O-CE2 3.27Å; S199-Y203 PolarHBondContact O-N 3.49Å; G200-Y203 PolarHBondContact O-N 2.86Å; Y203-S207 WeakPolarHBondContact O-CB 3.4Å; Y203-S207 PolarHBondContact O-N 2.73Å; Y203-A291 VanDerWaalsContact CE1-O 3.29Å; Y203-A291 WeakPolarHBondContact CE1-O 3.43Å; Y203-A291 WeakPolarHBondContact OH-CA 3.48Å; Y203-A291 VanDerWaalsContact OH-CB 3.25Å; Y203-A291 WeakPolarHBondContact OH-CB 3.4Å; Y203-A291 PolarHBondContact OH-O 3.21Å; Y203-P295 HydrophobicContact CD1-CG 4.14Å; Y203-P295 HydrophobicContact CE1-CG 4.16Å; Y203-S322 VanDerWaalsContact CB-O 3.24Å; Y203-S322 WeakPolarHBondContact CB-O 3.36Å; Y203-F325 HydrophobicContact CD1-CD1 4.38Å; Y203-F325 HydrophobicContact CD2-CD1 4.11Å; Y203-F325 HydrophobicContact CD2-CE1 4.46Å; Y203-F325 HydrophobicContact CE1-CD1 4.2Å; Y203-F325 HydrophobicContact CE1-CE1 4.22Å; Y203-F325 AromaticContact CE2-CD1 3.93Å; Y203-F325 HydrophobicContact CE2-CD1 3.93Å; Y203-F325 AromaticContact CE2-CE1 3.83Å; Y203-F325 HydrophobicContact CE2-CE1 3.83Å; Y203-F325 HydrophobicContact CG-CD1 4.34Å; Y203-F325 AromaticContact CZ-CD1 3.99Å; Y203-F325 AromaticContact CZ-CE1 3.7Å; Y203-T329 HydrophobicContact CE2-CG2 4.49Å
204	I	94	Very high	91.2	Very high	37 Å²	37	31.6 Å²	31.6	19%	0.19	19%	0.192	C	C	.	.	H	α-helix	trans	-64.8	-48.1	-179.8	-65.3	165.3	0	0	0	110.5	G200 L201 G202 K208 L323 L327	G200-I204 WeakPolarHBondContact O-CD1 3.44Å; G200-I204 VanDerWaalsContact O-CG1 3.29Å; G200-I204 WeakPolarHBondContact O-CG1 3.48Å; G200-I204 PolarHBondContact O-N 3.44Å; L201-I204 HydrophobicContact CD2-CD1 4.47Å; L201-I204 PolarHBondContact O-N 3.24Å; G202-I204 VanDerWaalsContact C-N 3.33Å; G202-I204 PolarHBondContact O-N 3.46Å; I204-K208 WeakPolarHBondContact O-CB 3.42Å; I204-K208 PolarHBondContact O-N 3.27Å; I204-L323 HydrophobicContact CG1-CG 4.46Å; I204-L327 HydrophobicContact CD1-CD2 3.88Å; I204-L327 HydrophobicContact CD1-CG 4.16Å
205	A	93.1	Very high	91.2	Very high	21 Å²	21	33.4 Å²	33.4	17%	0.174	20%	0.201	C	C	.	.	H	α-helix	trans	-62.5	-48	179	0	0	0	0	0	110.6	M74 L201 G202 S207 V209	M74-A205 HydrophobicContact CG-CB 4.33Å; M74-A205 HydrophobicContact SD-CB 4.21Å; L201-A205 WeakPolarHBondContact O-CB 3.19Å; L201-A205 PolarHBondContact O-N 2.99Å; G202-A205 PolarHBondContact O-N 3.43Å; A205-S207 PolarHBondContact O-N 2.97Å; A205-V209 WeakPolarHBondContact O-CB 3.42Å; A205-V209 WeakPolarHBondContact O-CG2 3.42Å; A205-V209 PolarHBondContact O-N 3.45Å
206	G	90.6	Very high	91.4	Very high	0 Å²	0	32 Å²	32	0%	0	19%	0.192	C	C	.	.	H	α-helix	trans	-57.8	-50.1	179.1	0	0	0	0	0	112.7	V82 G202 K210	V82-G206 WeakPolarHBondContact CG1-O 3.38Å; G202-G206 PolarHBondContact O-N 3Å; G206-K210 VanDerWaalsContact O-CB 3.31Å; G206-K210 WeakPolarHBondContact O-CB 3.3Å; G206-K210 PolarHBondContact O-N 3.11Å
207	S	90.4	Very high	91.6	Very high	0 Å²	0	31.8 Å²	31.8	0%	0	19%	0.189	C	C	.	.	H	α-helix	trans	-66.8	-49.9	179.2	165.5	0	0	0	0	112.6	Y203 A205 K210 D211 S319	Y203-S207 WeakPolarHBondContact O-CB 3.4Å; Y203-S207 PolarHBondContact O-N 2.73Å; A205-S207 PolarHBondContact O-N 2.97Å; S207-K210 WeakPolarHBondContact O-CB 3.4Å; S207-K210 PolarHBondContact O-N 2.85Å; S207-D211 PolarHBondContact O-N 3.38Å; S207-S319 PolarHBondContact OG-O 2.87Å
208	K	92	Very high	91.7	Very high	112 Å²	112	35.5 Å²	35.5	49%	0.487	20%	0.199	S	C	.	.	H	α-helix	trans	-72.4	-38.2	-172.1	-169.7	60.1	177.9	175	0	113	I204 K210 D211 V212	I204-K208 WeakPolarHBondContact O-CB 3.42Å; I204-K208 PolarHBondContact O-N 3.27Å; K208-K210 VanDerWaalsContact C-N 3.34Å; K208-D211 PolarHBondContact O-N 3.05Å; K208-V212 HydrophobicContact CD-CG2 4.41Å; K208-V212 VanDerWaalsContact O-CG2 3.29Å; K208-V212 WeakPolarHBondContact O-CG2 3.5Å; K208-V212 PolarHBondContact O-N 3.28Å
209	V	92.1	Very high	91.6	Very high	33 Å²	33	35.6 Å²	35.6	20%	0.2	20%	0.2	C	C	.	.	H	α-helix	trans	-64.4	-43.9	177	171.5	0	0	0	0	109.9	A205 V212 A213 W218 V222	A205-V209 WeakPolarHBondContact O-CB 3.42Å; A205-V209 WeakPolarHBondContact O-CG2 3.42Å; A205-V209 PolarHBondContact O-N 3.45Å; V209-V212 PolarHBondContact O-N 2.93Å; V209-A213 VanDerWaalsContact O-CB 3.25Å; V209-A213 WeakPolarHBondContact O-CB 3.39Å; V209-A213 PolarHBondContact O-N 3.21Å; V209-W218 HydrophobicContact CG1-CB 3.83Å; V209-W218 WeakPolarHBondContact CG1-O 3.5Å; V209-V222 HydrophobicContact CB-CG2 4.48Å; V209-V222 HydrophobicContact CG1-CB 4.43Å; V209-V222 HydrophobicContact CG1-CG2 3.58Å; V209-V222 HydrophobicContact CG2-CB 4.39Å; V209-V222 HydrophobicContact CG2-CG1 4.45Å; V209-V222 HydrophobicContact CG2-CG2 4.03Å
210	K	89.8	Confident	91.5	Very high	5 Å²	5	35.3 Å²	35.3	2%	0.022	20%	0.198	C	C	.	.	H	α-helix	trans	-56	-52.6	173.1	174.7	-171.7	78.6	-171.6	0	111.3	V82 D85 G206 S207 K208 V212 A213 G214 D215 W216 C317	V82-K210 HydrophobicContact CG1-CB 4.09Å; V82-K210 HydrophobicContact CG1-CD 4.05Å; D85-K210 IonicContact OD1-NZ 3.39Å; D85-K210 WeakPolarHBondContact OD2-CD 3.42Å; D85-K210 WeakPolarHBondContact OD2-CE 3.27Å; D85-K210 IonicContact OD2-NZ 2.74Å; D85-K210 PolarHBondContact OD2-NZ 3.43Å; G206-K210 VanDerWaalsContact O-CB 3.31Å; G206-K210 WeakPolarHBondContact O-CB 3.3Å; G206-K210 PolarHBondContact O-N 3.11Å; S207-K210 WeakPolarHBondContact O-CB 3.4Å; S207-K210 PolarHBondContact O-N 2.85Å; K208-K210 VanDerWaalsContact C-N 3.34Å; K210-V212 VanDerWaalsContact C-N 3.28Å; K210-V212 PolarHBondContact O-N 3Å; K210-A213 PolarHBondContact O-N 2.78Å; K210-G214 WeakPolarHBondContact O-CA 3.13Å; K210-G214 PolarHBondContact O-N 2.85Å; K210-D215 PolarHBondContact O-N 3.16Å; K210-W216 HydrophobicContact CD-CB 3.89Å; K210-W216 HydrophobicContact CG-CB 4.07Å; K210-C317 VanDerWaalsContact CE-O 3.26Å; K210-C317 WeakPolarHBondContact CE-O 3.49Å; K210-C317 PolarHBondContact NZ-O 3.5Å
211	D	88.5	Confident	91.6	Very high	51 Å²	51	38.1 Å²	38.1	27%	0.273	21%	0.208	S	C	.	.	H	α-helix	trans	-61.9	-36.6	-175	-66.1	-13.4	0	0	0	112.3	S207 K208	S207-D211 PolarHBondContact O-N 3.38Å; K208-D211 PolarHBondContact O-N 3.05Å
212	V	89.7	Confident	91.4	Very high	115 Å²	115	37.8 Å²	37.8	70%	0.697	21%	0.208	S	C	*	.	H	α-helix	trans	-74.8	-38	178.3	173.4	0	0	0	0	111.8	K208 V209 K210	K208-V212 HydrophobicContact CD-CG2 4.41Å; K208-V212 VanDerWaalsContact O-CG2 3.29Å; K208-V212 WeakPolarHBondContact O-CG2 3.5Å; K208-V212 PolarHBondContact O-N 3.28Å; V209-V212 PolarHBondContact O-N 2.93Å; K210-V212 VanDerWaalsContact C-N 3.28Å; K210-V212 PolarHBondContact O-N 3Å
213	A	89.3	Confident	91.2	Very high	47 Å²	47	38.3 Å²	38.3	39%	0.388	21%	0.212	S	C	.	.	H	α-helix	trans	-85	-15.4	-178.4	0	0	0	0	0	113.7	V209 K210 D215 W218	V209-A213 VanDerWaalsContact O-CB 3.25Å; V209-A213 WeakPolarHBondContact O-CB 3.39Å; V209-A213 PolarHBondContact O-N 3.21Å; K210-A213 PolarHBondContact O-N 2.78Å; A213-D215 PolarHBondContact O-N 2.99Å; A213-W218 HydrophobicContact CB-CB 3.68Å; A213-W218 HydrophobicContact CB-CD2 4.36Å; A213-W218 HydrophobicContact CB-CG 3.57Å
214	G	86.4	Confident	91.2	Very high	46 Å²	46	38.6 Å²	38.6	47%	0.474	21%	0.214	S	C	.	.	T	Hydrogen-bonded Turn	trans	69.3	9.7	-173.3	0	0	0	0	0	114.2	K210	K210-G214 WeakPolarHBondContact O-CA 3.13Å; K210-G214 PolarHBondContact O-N 2.85Å
215	D	89.5	Confident	91.1	Very high	50 Å²	50	38.9 Å²	38.9	27%	0.267	23%	0.226	S	C	.	.	S	Bend	trans	-149.6	126.1	-175.2	173.3	13.6	0	0	0	110.7	K210 A213 H217 W218	K210-D215 PolarHBondContact O-N 3.16Å; A213-D215 PolarHBondContact O-N 2.99Å; D215-H217 PolarHBondContact O-N 2.56Å; D215-H217 IonicContact OD1-CE1 3.55Å; D215-H217 IonicContact OD1-CG 3.14Å; D215-H217 PolarHBondContact OD1-N 2.81Å; D215-H217 IonicContact OD1-ND1 3.91Å; D215-H217 PolarHBondContact OD1-ND1 3.4Å; D215-H217 IonicContact OD2-ND1 3.96Å; D215-H217 PolarHBondContact OD2-ND1 3.05Å; D215-W218 PolarHBondContact O-N 2.93Å
216	W	91.2	Very high	91.1	Very high	14 Å²	14	40.7 Å²	40.7	5%	0.053	23%	0.232	C	C	.	.	G	3₁₀ helix	trans	-65.5	-25.1	-176.8	72.6	-93.5	0	0	0	112.9	V82 D85 I86 F89 F90 K210 W218 A219 L220	V82-W216 HydrophobicContact CB-CB 4.22Å; V82-W216 HydrophobicContact CG1-CB 4.45Å; V82-W216 HydrophobicContact CG2-CE3 4.31Å; D85-W216 HydrophobicContact CB-CB 3.67Å; D85-W216 HydrophobicContact CB-CD2 4.5Å; D85-W216 HydrophobicContact CB-CG 3.68Å; I86-W216 HydrophobicContact CD1-CE3 4.27Å; I86-W216 HydrophobicContact CD1-CZ3 4.03Å; I86-W216 HydrophobicContact CG1-CD2 4.24Å; I86-W216 HydrophobicContact CG1-CE3 3.76Å; I86-W216 HydrophobicContact CG1-CH2 4.07Å; I86-W216 HydrophobicContact CG1-CZ2 4.49Å; I86-W216 HydrophobicContact CG1-CZ3 3.67Å; F89-W216 HydrophobicContact CB-CZ2 4.29Å; F89-W216 AromaticContact CD1-CZ2 3.75Å; F89-W216 HydrophobicContact CD1-CZ2 3.75Å; F89-W216 HydrophobicContact CD2-CZ2 4.49Å; F89-W216 AromaticContact CD2-NE1 3.93Å; F89-W216 HydrophobicContact CE1-CZ2 4.12Å; F89-W216 AromaticContact CG-CZ2 3.94Å; F89-W216 HydrophobicContact CG-CZ2 3.94Å; F89-W216 AromaticContact CG-NE1 3.88Å; F90-W216 HydrophobicContact CE2-CH2 4.02Å; F90-W216 HydrophobicContact CE2-CZ2 4.14Å; K210-W216 HydrophobicContact CD-CB 3.89Å; K210-W216 HydrophobicContact CG-CB 4.07Å; W216-W218 PolarHBondContact O-N 3.28Å; W216-W218 VanDerWaalsContact O-N 3.14Å; W216-A219 WeakPolarHBondContact O-CB 3.4Å; W216-A219 PolarHBondContact O-N 2.8Å; W216-L220 HydrophobicContact CE3-CD1 4.44Å; W216-L220 HydrophobicContact CZ3-CD1 3.71Å; W216-L220 HydrophobicContact CZ3-CG 4.48Å
217	H	93	Very high	91.3	Very high	21 Å²	21	40.8 Å²	40.8	10%	0.097	23%	0.233	C	C	.	.	G	3₁₀ helix	trans	-59.8	-28.5	178.1	-61.9	93	0	0	0	111.8	F89 S143 D215 A219 L220 R221	F89-H217 AromaticContact CE2-CE1 3.82Å; F89-H217 AromaticContact CZ-CE1 3.95Å; F89-H217 AromaticContact CZ-NE2 3.77Å; S143-H217 PolarHBondContact O-CD2 3.22Å; D215-H217 PolarHBondContact O-N 2.56Å; D215-H217 IonicContact OD1-CE1 3.55Å; D215-H217 IonicContact OD1-CG 3.14Å; D215-H217 PolarHBondContact OD1-N 2.81Å; D215-H217 IonicContact OD1-ND1 3.91Å; D215-H217 PolarHBondContact OD1-ND1 3.4Å; D215-H217 IonicContact OD2-ND1 3.96Å; D215-H217 PolarHBondContact OD2-ND1 3.05Å; H217-A219 VanDerWaalsContact C-N 3.27Å; H217-A219 PolarHBondContact O-N 3.28Å; H217-L220 PolarHBondContact O-N 3.2Å; H217-L220 VanDerWaalsContact O-N 3.11Å; H217-R221 WeakPolarHBondContact O-CG 3.49Å; H217-R221 PolarHBondContact O-N 3.11Å
218	W	92.4	Very high	91.5	Very high	118 Å²	118	44.9 Å²	44.9	45%	0.447	26%	0.258	S	S	.	.	G	3₁₀ helix	trans	-66.3	-27	177.3	-77.3	95.7	0	0	0	113.7	V209 A213 D215 W216 L220 R221 V222	V209-W218 HydrophobicContact CG1-CB 3.83Å; V209-W218 WeakPolarHBondContact CG1-O 3.5Å; A213-W218 HydrophobicContact CB-CB 3.68Å; A213-W218 HydrophobicContact CB-CD2 4.36Å; A213-W218 HydrophobicContact CB-CG 3.57Å; D215-W218 PolarHBondContact O-N 2.93Å; W216-W218 PolarHBondContact O-N 3.28Å; W216-W218 VanDerWaalsContact O-N 3.14Å; W218-L220 PolarHBondContact O-N 3.37Å; W218-R221 HydrophobicContact CE3-CB 4.08Å; W218-R221 PolarHBondContact O-N 3.26Å; W218-V222 PolarHBondContact O-N 2.95Å; W218-V222 VanDerWaalsContact O-N 3.16Å
219	A	91.6	Very high	91.6	Very high	2 Å²	2	42.8 Å²	42.8	2%	0.017	25%	0.254	C	S	.	.	H	α-helix	trans	-55.8	-39	171.6	0	0	0	0	0	111.1	T78 V82 W216 H217	T78-A219 HydrophobicContact CG2-CB 3.9Å; T78-A219 WeakPolarHBondContact CG2-O 3.37Å; V82-A219 HydrophobicContact CG1-CB 3.74Å; V82-A219 HydrophobicContact CG2-CB 4.35Å; W216-A219 WeakPolarHBondContact O-CB 3.4Å; W216-A219 PolarHBondContact O-N 2.8Å; H217-A219 VanDerWaalsContact C-N 3.27Å; H217-A219 PolarHBondContact O-N 3.28Å
220	L	92	Very high	91.7	Very high	4 Å²	4	41.2 Å²	41.2	2%	0.021	25%	0.245	C	C	.	.	H	α-helix	trans	-84.8	-5	178.3	-55.7	-177	0	0	0	113.9	T78 V79 T139 W216 H217 W218 P224	T78-L220 HydrophobicContact CG2-CD2 4.24Å; V79-L220 HydrophobicContact CG2-CD2 3.91Å; T139-L220 HydrophobicContact CG2-CB 4.46Å; W216-L220 HydrophobicContact CE3-CD1 4.44Å; W216-L220 HydrophobicContact CZ3-CD1 3.71Å; W216-L220 HydrophobicContact CZ3-CG 4.48Å; H217-L220 PolarHBondContact O-N 3.2Å; H217-L220 VanDerWaalsContact O-N 3.11Å; W218-L220 PolarHBondContact O-N 3.37Å; L220-P224 WeakPolarHBondContact O-CD 3.27Å; L220-P224 WeakPolarHBondContact O-CG 3.41Å
221	R	94.1	Very high	92	Very high	59 Å²	59	42.5 Å²	42.5	22%	0.223	25%	0.253	C	S	.	.	H	α-helix	trans	-99.7	-23.4	179.4	-66.8	175.2	-174.9	159	8.2	113.3	L140 S143 H217 W218 P224	L140-R221 HydrophobicContact CD1-CB 4.39Å; L140-R221 HydrophobicContact CD1-CG 4Å; S143-R221 PolarHBondContact O-NH2 2.62Å; S143-R221 VanDerWaalsContact O-NH2 3.11Å; S143-R221 VanDerWaalsContact OG-CG 3.3Å; S143-R221 WeakPolarHBondContact OG-CG 3.45Å; S143-R221 PolarHBondContact OG-NE 3.13Å; S143-R221 VanDerWaalsContact OG-NE 3.08Å; H217-R221 WeakPolarHBondContact O-CG 3.49Å; H217-R221 PolarHBondContact O-N 3.11Å; W218-R221 HydrophobicContact CE3-CB 4.08Å; W218-R221 PolarHBondContact O-N 3.26Å; R221-P224 WeakPolarHBondContact O-CD 3.34Å
222	V	91.8	Very high	92.4	Very high	55 Å²	55	44.7 Å²	44.7	33%	0.333	26%	0.264	S	S	.	.	H	α-helix	trans	-75.7	-42	179.2	170.2	0	0	0	0	111.9	V209 W218 G225 L226	V209-V222 HydrophobicContact CB-CG2 4.48Å; V209-V222 HydrophobicContact CG1-CB 4.43Å; V209-V222 HydrophobicContact CG1-CG2 3.58Å; V209-V222 HydrophobicContact CG2-CB 4.39Å; V209-V222 HydrophobicContact CG2-CG1 4.45Å; V209-V222 HydrophobicContact CG2-CG2 4.03Å; W218-V222 PolarHBondContact O-N 2.95Å; W218-V222 VanDerWaalsContact O-N 3.16Å; V222-G225 PolarHBondContact O-N 3.35Å; V222-G225 VanDerWaalsContact O-N 3.16Å; V222-L226 HydrophobicContact CG1-CD1 4.43Å; V222-L226 PolarHBondContact O-N 2.71Å
223	T	89.9	Confident	92.6	Very high	12 Å²	12	42.2 Å²	42.2	7%	0.074	25%	0.247	C	C	.	.	H	α-helix	trans	-63.6	-38.9	-178.1	59	0	0	0	0	113.3	M74 D75 G225 L226 G227	M74-T223 HydrophobicContact CE-CG2 3.89Å; D75-T223 WeakPolarHBondContact OD1-CB 3.3Å; D75-T223 PolarHBondContact OD1-OG1 3.22Å; T223-G225 VanDerWaalsContact C-N 3.32Å; T223-G225 PolarHBondContact O-N 3.48Å; T223-L226 PolarHBondContact O-N 3.19Å; T223-G227 PolarHBondContact O-N 3.38Å
224	P	93.3	Very high	92.8	Very high	8 Å²	8	40 Å²	40	5%	0.052	23%	0.229	C	C	.	.	H	α-helix	trans	-60.9	-35.9	172	-26.7	37.5	0	0	0	114.1	S136 T139 L140 L220 R221 L226 G227 V228	S136-P224 WeakPolarHBondContact O-CB 3.49Å; S136-P224 WeakPolarHBondContact O-CG 3.47Å; T139-P224 HydrophobicContact CG2-CG 3.99Å; L140-P224 HydrophobicContact CB-CB 4Å; L140-P224 HydrophobicContact CB-CG 3.8Å; L220-P224 WeakPolarHBondContact O-CD 3.27Å; L220-P224 WeakPolarHBondContact O-CG 3.41Å; R221-P224 WeakPolarHBondContact O-CD 3.34Å; P224-L226 VanDerWaalsContact C-N 3.32Å; P224-L226 PolarHBondContact O-N 3.41Å; P224-G227 CarbonylContact O-C 3.49Å; P224-G227 WeakPolarHBondContact O-CA 3.19Å; P224-G227 PolarHBondContact O-N 3.41Å; P224-G227 VanDerWaalsContact O-N 3.11Å; P224-V228 PolarHBondContact O-N 3.28Å
225	G	92.3	Very high	93.2	Very high	43 Å²	43	42.6 Å²	42.6	44%	0.443	23%	0.227	S	C	.	.	H	α-helix	trans	-61.8	-41.8	176.5	0	0	0	0	0	112	V222 T223 G227 V228 V229	V222-G225 PolarHBondContact O-N 3.35Å; V222-G225 VanDerWaalsContact O-N 3.16Å; T223-G225 VanDerWaalsContact C-N 3.32Å; T223-G225 PolarHBondContact O-N 3.48Å; G225-G227 VanDerWaalsContact C-N 3.34Å; G225-V228 PolarHBondContact O-N 3.02Å; G225-V229 PolarHBondContact O-N 2.9Å
226	L	93.5	Very high	93.5	Very high	60 Å²	60	46.6 Å²	46.6	31%	0.314	25%	0.248	S	C	.	.	H	α-helix	trans	-68.5	-35	172.3	-59.8	174.4	0	0	0	111.7	Y67 L71 M74 V222 T223 P224 V228 V229 A230	Y67-L226 PolarHBondContact OH-O 2.96Å; L71-L226 HydrophobicContact CD1-CB 3.93Å; L71-L226 HydrophobicContact CD2-CB 3.62Å; L71-L226 HydrophobicContact CD2-CD1 3.74Å; L71-L226 HydrophobicContact CD2-CG 4.3Å; L71-L226 HydrophobicContact CG-CB 4.45Å; M74-L226 HydrophobicContact CE-CD1 3.5Å; M74-L226 VanDerWaalsContact CE-CD1 3.5Å; V222-L226 HydrophobicContact CG1-CD1 4.43Å; V222-L226 PolarHBondContact O-N 2.71Å; T223-L226 PolarHBondContact O-N 3.19Å; P224-L226 VanDerWaalsContact C-N 3.32Å; P224-L226 PolarHBondContact O-N 3.41Å; L226-V228 VanDerWaalsContact C-N 3.33Å; L226-V228 PolarHBondContact O-N 2.97Å; L226-V229 WeakPolarHBondContact O-CB 3.43Å; L226-V229 PolarHBondContact O-N 2.94Å; L226-A230 PolarHBondContact O-N 3Å
227	G	93.8	Very high	93.5	Very high	2 Å²	2	47.2 Å²	47.2	2%	0.021	25%	0.253	C	S	.	.	H	α-helix	trans	-57.6	-40.5	172.7	0	0	0	0	0	113.3	T223 P224 G225 V229 A230 V231	T223-G227 PolarHBondContact O-N 3.38Å; P224-G227 CarbonylContact O-C 3.49Å; P224-G227 WeakPolarHBondContact O-CA 3.19Å; P224-G227 PolarHBondContact O-N 3.41Å; P224-G227 VanDerWaalsContact O-N 3.11Å; G225-G227 VanDerWaalsContact C-N 3.34Å; G227-V229 PolarHBondContact O-N 3.35Å; G227-A230 CarbonylContact O-C 3.59Å; G227-A230 WeakPolarHBondContact O-CA 3.37Å; G227-A230 VanDerWaalsContact O-CB 3.25Å; G227-A230 WeakPolarHBondContact O-CB 3.47Å; G227-A230 PolarHBondContact O-N 2.77Å; G227-A230 VanDerWaalsContact O-N 3.11Å; G227-V231 WeakPolarHBondContact O-CG2 3.42Å; G227-V231 PolarHBondContact O-N 3.43Å
228	V	94.5	Very high	93.5	Very high	86 Å²	86	46.2 Å²	46.2	52%	0.521	25%	0.248	S	C	.	.	H	α-helix	trans	-61.1	-45.3	174.6	174.2	0	0	0	0	111.1	P224 G225 L226 A230 V231 L232	P224-V228 PolarHBondContact O-N 3.28Å; G225-V228 PolarHBondContact O-N 3.02Å; L226-V228 VanDerWaalsContact C-N 3.33Å; L226-V228 PolarHBondContact O-N 2.97Å; V228-A230 VanDerWaalsContact C-N 3.25Å; V228-A230 PolarHBondContact O-N 3.49Å; V228-V231 PolarHBondContact O-N 3.24Å; V228-L232 HydrophobicContact CG1-CD1 4.25Å; V228-L232 WeakPolarHBondContact O-CG 3.16Å; V228-L232 PolarHBondContact O-N 3.47Å
229	V	95.7	Very high	93.3	Very high	67 Å²	67	45.4 Å²	45.4	41%	0.406	25%	0.25	S	C	.	.	H	α-helix	trans	-60	-41	174.4	-179.7	0	0	0	0	110.2	G225 L226 G227 L232 L233	G225-V229 PolarHBondContact O-N 2.9Å; L226-V229 WeakPolarHBondContact O-CB 3.43Å; L226-V229 PolarHBondContact O-N 2.94Å; G227-V229 PolarHBondContact O-N 3.35Å; V229-L232 PolarHBondContact O-N 2.92Å; V229-L233 HydrophobicContact CG1-CD1 3.93Å; V229-L233 HydrophobicContact CG1-CG 4.22Å; V229-L233 WeakPolarHBondContact O-CB 3.3Å; V229-L233 VanDerWaalsContact O-CG 3.3Å; V229-L233 WeakPolarHBondContact O-CG 3.12Å; V229-L233 PolarHBondContact O-N 3.34Å
230	A	94.3	Very high	92.9	Very high	0 Å²	0	47.8 Å²	47.8	0%	0	26%	0.26	C	S	.	.	H	α-helix	trans	-61.5	-44	177.1	0	0	0	0	0	112.7	Y67 I68 L71 I132 L226 G227 V228 L233 L234	Y67-A230 HydrophobicContact CD1-CB 4.29Å; Y67-A230 HydrophobicContact CE1-CB 3.8Å; I68-A230 HydrophobicContact CG1-CB 3.79Å; L71-A230 HydrophobicContact CD1-CB 3.74Å; I132-A230 HydrophobicContact CG2-CB 4.41Å; L226-A230 PolarHBondContact O-N 3Å; G227-A230 CarbonylContact O-C 3.59Å; G227-A230 WeakPolarHBondContact O-CA 3.37Å; G227-A230 VanDerWaalsContact O-CB 3.25Å; G227-A230 WeakPolarHBondContact O-CB 3.47Å; G227-A230 PolarHBondContact O-N 2.77Å; G227-A230 VanDerWaalsContact O-N 3.11Å; V228-A230 VanDerWaalsContact C-N 3.25Å; V228-A230 PolarHBondContact O-N 3.49Å; A230-L233 PolarHBondContact O-N 3.44Å; A230-L234 VanDerWaalsContact O-CB 3.3Å; A230-L234 WeakPolarHBondContact O-CB 3.06Å; A230-L234 PolarHBondContact O-N 3.02Å
231	V	95.6	Very high	92.4	Very high	32 Å²	32	47.7 Å²	47.7	19%	0.194	26%	0.26	C	S	.	.	H	α-helix	trans	-62.2	-45.3	174.6	176.6	0	0	0	0	110.9	I132 A133 G227 V228 L234 F235	I132-V231 HydrophobicContact CB-CG2 3.71Å; I132-V231 HydrophobicContact CG2-CG2 3.36Å; A133-V231 HydrophobicContact CB-CG2 4.39Å; G227-V231 WeakPolarHBondContact O-CG2 3.42Å; G227-V231 PolarHBondContact O-N 3.43Å; V228-V231 PolarHBondContact O-N 3.24Å; V231-L234 PolarHBondContact O-N 3.31Å; V231-F235 VanDerWaalsContact O-CB 3.25Å; V231-F235 WeakPolarHBondContact O-CB 3.44Å; V231-F235 PolarHBondContact O-N 2.91Å
232	L	95.6	Very high	91.4	Very high	97 Å²	97	48.2 Å²	48.2	51%	0.508	27%	0.271	S	S	.	.	H	α-helix	trans	-62.7	-47	179.4	-70.3	173.5	0	0	0	111.3	V228 V229 F235 L236	V228-L232 HydrophobicContact CG1-CD1 4.25Å; V228-L232 WeakPolarHBondContact O-CG 3.16Å; V228-L232 PolarHBondContact O-N 3.47Å; V229-L232 PolarHBondContact O-N 2.92Å; L232-F235 PolarHBondContact O-N 2.99Å; L232-L236 VanDerWaalsContact O-CB 3.3Å; L232-L236 WeakPolarHBondContact O-CB 3.37Å; L232-L236 WeakPolarHBondContact O-CG 3.29Å; L232-L236 PolarHBondContact O-N 2.87Å
233	L	94.9	Very high	90.5	Very high	64 Å²	64	50 Å²	50	34%	0.335	27%	0.272	S	S	.	.	H	α-helix	trans	-61.6	-44.9	176.3	-71.1	176	0	0	0	111.2	V64 Y67 V229 A230 F235 L236 V237	V64-L233 HydrophobicContact CG1-CB 3.98Å; V64-L233 HydrophobicContact CG2-CB 4.28Å; Y67-L233 HydrophobicContact CD1-CD1 4.23Å; Y67-L233 HydrophobicContact CE1-CD1 4.22Å; V229-L233 HydrophobicContact CG1-CD1 3.93Å; V229-L233 HydrophobicContact CG1-CG 4.22Å; V229-L233 WeakPolarHBondContact O-CB 3.3Å; V229-L233 VanDerWaalsContact O-CG 3.3Å; V229-L233 WeakPolarHBondContact O-CG 3.12Å; V229-L233 PolarHBondContact O-N 3.34Å; A230-L233 PolarHBondContact O-N 3.44Å; L233-F235 VanDerWaalsContact C-N 3.34Å; L233-F235 PolarHBondContact O-N 3.37Å; L233-L236 PolarHBondContact O-N 3.43Å; L233-V237 HydrophobicContact CD2-CG2 4.46Å; L233-V237 WeakPolarHBondContact O-CB 3.01Å; L233-V237 WeakPolarHBondContact O-CG2 3.46Å; L233-V237 PolarHBondContact O-N 2.94Å
234	L	94.2	Very high	89.3	Confident	0 Å²	0	50.3 Å²	50.3	0%	0	28%	0.277	C	S	.	.	H	α-helix	trans	-63.4	-42	177.8	-167.3	138.8	0	0	0	111.4	V64 L65 I68 K125 M128 C129 I132 A230 V231 V238	V64-L234 HydrophobicContact CG1-CB 4.49Å; L65-L234 HydrophobicContact CD2-CD1 4.33Å; I68-L234 HydrophobicContact CD1-CB 4.07Å; I68-L234 HydrophobicContact CD1-CD1 3.43Å; I68-L234 VanDerWaalsContact CD1-CD1 3.43Å; I68-L234 HydrophobicContact CD1-CG 4.32Å; K125-L234 HydrophobicContact CG-CD2 3.82Å; K125-L234 WeakPolarHBondContact O-CD2 3.47Å; M128-L234 HydrophobicContact CB-CD1 3.92Å; M128-L234 HydrophobicContact CB-CD2 4.19Å; M128-L234 HydrophobicContact CE-CD1 4.02Å; M128-L234 HydrophobicContact SD-CD1 4.2Å; C129-L234 HydrophobicContact CB-CD2 4.42Å; C129-L234 WeakPolarHBondContact SG-CD2 3.31Å; I132-L234 HydrophobicContact CD1-CD1 3.85Å; A230-L234 VanDerWaalsContact O-CB 3.3Å; A230-L234 WeakPolarHBondContact O-CB 3.06Å; A230-L234 PolarHBondContact O-N 3.02Å; V231-L234 PolarHBondContact O-N 3.31Å; L234-V238 HydrophobicContact CB-CG2 4.5Å; L234-V238 HydrophobicContact CG-CB 4.29Å; L234-V238 HydrophobicContact CG-CG2 3.97Å; L234-V238 WeakPolarHBondContact O-CB 3.38Å; L234-V238 PolarHBondContact O-N 3.38Å; L234-V238 VanDerWaalsContact O-N 3.15Å
235	F	94.7	Very high	87.6	Confident	101 Å²	101	50.7 Å²	50.7	44%	0.443	28%	0.281	S	S	.	.	H	α-helix	trans	-69	-39.4	179.9	-170.1	-91.7	0	0	0	112.9	K125 Y126 V231 L232 L233	K125-F235 WeakPolarHBondContact CE-O 3.46Å; K125-F235 PolarHBondContact NZ-O 3.08Å; Y126-F235 HydrophobicContact CD1-CE2 4.45Å; Y126-F235 HydrophobicContact CE1-CD2 4.38Å; Y126-F235 AromaticContact CE1-CE2 3.81Å; Y126-F235 HydrophobicContact CE1-CE2 3.81Å; V231-F235 VanDerWaalsContact O-CB 3.25Å; V231-F235 WeakPolarHBondContact O-CB 3.44Å; V231-F235 PolarHBondContact O-N 2.91Å; L232-F235 PolarHBondContact O-N 2.99Å; L233-F235 VanDerWaalsContact C-N 3.34Å; L233-F235 PolarHBondContact O-N 3.37Å
236	L	94.3	Very high	86	Confident	134 Å²	134	48.9 Å²	48.9	70%	0.702	26%	0.261	S	S	*	.	H	α-helix	trans	-84.1	-38.5	-176	-65.2	174	0	0	0	112.9	L232 L233	L232-L236 VanDerWaalsContact O-CB 3.3Å; L232-L236 WeakPolarHBondContact O-CB 3.37Å; L232-L236 WeakPolarHBondContact O-CG 3.29Å; L232-L236 PolarHBondContact O-N 2.87Å; L233-L236 PolarHBondContact O-N 3.43Å
237	V	93.1	Very high	84.2	Confident	27 Å²	27	51.1 Å²	51.1	16%	0.164	27%	0.27	C	S	.	.	H	α-helix	trans	-95.8	-40	-170.6	-178.9	0	0	0	0	112.1	H57 L60 V64 L233 Q239	H57-V237 PolarHBondContact NE2-O 3.14Å; L60-V237 HydrophobicContact CD2-CG1 3.59Å; L60-V237 HydrophobicContact CG-CG1 3.67Å; V64-V237 HydrophobicContact CG2-CB 4.2Å; V64-V237 HydrophobicContact CG2-CG1 4.05Å; V64-V237 HydrophobicContact CG2-CG2 4.42Å; L233-V237 HydrophobicContact CD2-CG2 4.46Å; L233-V237 WeakPolarHBondContact O-CB 3.01Å; L233-V237 WeakPolarHBondContact O-CG2 3.46Å; L233-V237 PolarHBondContact O-N 2.94Å; V237-Q239 PolarHBondContact O-N 2.61Å
238	V	91.3	Very high	82.1	Confident	0 Å²	0	61.2 Å²	61.2	0%	0	31%	0.307	C	S	.	.			trans	-77.6	122.9	-173.3	-177.1	0	0	0	0	110.1	I61 V64 K125 L174 L234	I61-V238 HydrophobicContact CG1-CG2 4.42Å; I61-V238 HydrophobicContact CG2-CG1 4.18Å; I61-V238 HydrophobicContact CG2-CG2 4.11Å; V64-V238 HydrophobicContact CG1-CG2 4.25Å; K125-V238 VanDerWaalsContact CD-O 3.28Å; K125-V238 WeakPolarHBondContact CD-O 3.31Å; K125-V238 WeakPolarHBondContact CE-O 3.49Å; K125-V238 PolarHBondContact NZ-O 3.22Å; L174-V238 HydrophobicContact CD2-CG1 3.69Å; L234-V238 HydrophobicContact CB-CG2 4.5Å; L234-V238 HydrophobicContact CG-CB 4.29Å; L234-V238 HydrophobicContact CG-CG2 3.97Å; L234-V238 WeakPolarHBondContact O-CB 3.38Å; L234-V238 PolarHBondContact O-N 3.38Å; L234-V238 VanDerWaalsContact O-N 3.15Å
239	Q	88.3	Confident	79.7	Confident	101 Å²	101	63.2 Å²	63.2	47%	0.472	31%	0.311	S	S	.	.			trans	-107.4	136	169.3	-66.8	-170.3	-9.6	0	0	108.2	L53 V237 P241	L53-Q239 HydrophobicContact CD2-CB 4.05Å; L53-Q239 HydrophobicContact CD2-CG 4.45Å; V237-Q239 PolarHBondContact O-N 2.61Å; Q239-P241 WeakPolarHBondContact O-CD 3.49Å
240	E	84.6	Confident	77.3	Confident	51 Å²	51	62.8 Å²	62.8	24%	0.238	31%	0.311	C	S	.	.			trans	-74.2	112	-179.1	-175.4	72.1	-160.3	0	0	109.1	R124 K125	R124-E240 WeakPolarHBondContact CB-OE2 3.33Å; R124-E240 IonicContact CZ-OE1 2.7Å; R124-E240 PolarHBondContact N-OE2 3.47Å; R124-E240 IonicContact NE-OE1 2.82Å; R124-E240 PolarHBondContact NE-OE1 3.16Å; R124-E240 IonicContact NH2-OE1 3.49Å; R124-E240 PolarHBondContact NH2-OE1 3.35Å; K125-E240 PolarHBondContact N-OE2 3.01Å; K125-E240 VanDerWaalsContact N-OE2 3.11Å
241	P	81.5	Confident	74.8	Confident	2 Å²	2	65.1 Å²	65.1	1%	0.013	34%	0.335	C	S	.	.	P	Polyproline II helix	trans	-73.1	154.6	175	32.7	-33.8	0	0	0	110	L174 D177 L178 Q239 R243	L174-P241 HydrophobicContact CD1-CG 3.66Å; D177-P241 HydrophobicContact CB-CG 3.96Å; L178-P241 HydrophobicContact CD2-CB 4.05Å; L178-P241 HydrophobicContact CD2-CG 3.99Å; L178-P241 HydrophobicContact CG-CG 4.29Å; Q239-P241 WeakPolarHBondContact O-CD 3.49Å; P241-R243 PolarHBondContact O-N 3.28Å
242	P	73.4	Confident	72.5	Confident	70 Å²	70	68 Å²	68	46%	0.455	36%	0.357	S	S	.	.	P	Polyproline II helix	trans	-59.7	123.8	172.9	-20.5	33.3	0	0	0	110.6	A245	P242-A245 HydrophobicContact CB-CB 3.89Å; P242-A245 VanDerWaalsContact O-CB 3.23Å; P242-A245 WeakPolarHBondContact O-CB 3.32Å; P242-A245 PolarHBondContact O-N 3.28Å
243	R	72.7	Confident	70	Confident	94 Å²	94	68.4 Å²	68.4	36%	0.355	37%	0.365	S	S	.	.	T	Hydrogen-bonded Turn	trans	-61.7	134.8	-173.1	-64.2	-174.4	-173.2	137.9	9.1	112.7	D120 R121 Y122 P241 A245	D120-R243 PolarHBondContact O-NH1 3.45Å; R121-R243 VanDerWaalsContact C-NH2 3.27Å; R121-R243 PolarHBondContact O-NH1 3.48Å; R121-R243 PolarHBondContact O-NH2 3.36Å; Y122-R243 PolarHBondContact O-NH2 2.92Å; P241-R243 PolarHBondContact O-N 3.28Å; R243-A245 PolarHBondContact O-N 3.21Å
244	G	64.2	Low	67.5	Low	17 Å²	17	71.5 Å²	71.5	18%	0.175	39%	0.389	C	S	.	.	T	Hydrogen-bonded Turn	trans	58.1	13.7	175.3	0	0	0	0	0	113.7	D177 V246 E247 R248	D177-G244 WeakPolarHBondContact OD1-CA 3.4Å; D177-G244 PolarHBondContact OD1-N 3.38Å; G244-V246 PolarHBondContact O-N 3.14Å; G244-E247 PolarHBondContact O-N 2.85Å; G244-E247 VanDerWaalsContact O-N 3.17Å; G244-R248 WeakPolarHBondContact O-CB 3.4Å; G244-R248 WeakPolarHBondContact O-CG 3.38Å; G244-R248 PolarHBondContact O-N 3.5Å
245	A	58	Low	65.6	Low	17 Å²	17	77 Å²	77	14%	0.14	42%	0.418	C	S	.	.	T	Hydrogen-bonded Turn	trans	-66.4	-25.2	-176.6	0	0	0	0	0	111.5	I50 P242 R243 H249	I50-A245 HydrophobicContact CG2-CB 3.41Å; I50-A245 VanDerWaalsContact CG2-CB 3.41Å; P242-A245 HydrophobicContact CB-CB 3.89Å; P242-A245 VanDerWaalsContact O-CB 3.23Å; P242-A245 WeakPolarHBondContact O-CB 3.32Å; P242-A245 PolarHBondContact O-N 3.28Å; R243-A245 PolarHBondContact O-N 3.21Å; A245-H249 PolarHBondContact O-ND1 3.2Å
246	V	57	Low	63.8	Low	4 Å²	4	76.8 Å²	76.8	2%	0.024	43%	0.428	C	S	.	.	T	Hydrogen-bonded Turn	trans	-79.5	-40.5	174.2	178.3	0	0	0	0	112.2	D177 V180 G244 S250	D177-V246 VanDerWaalsContact O-CG2 3.23Å; D177-V246 WeakPolarHBondContact O-CG2 3.42Å; V180-V246 HydrophobicContact CB-CG1 4.33Å; V180-V246 HydrophobicContact CG1-CB 4.47Å; V180-V246 HydrophobicContact CG1-CG1 3.08Å; G244-V246 PolarHBondContact O-N 3.14Å; V246-S250 PolarHBondContact O-OG 3.49Å
247	E	56.2	Low	62	Low	108 Å²	108	76.6 Å²	76.6	51%	0.505	44%	0.435	S	S	.	.	T	Hydrogen-bonded Turn	trans	-79	-30.9	-178.7	-75	-175.8	160.6	0	0	113.4	R184 G244 H249 S250	R184-E247 IonicContact NH1-OE1 3.29Å; R184-E247 PolarHBondContact NH1-OE1 3.32Å; G244-E247 PolarHBondContact O-N 2.85Å; G244-E247 VanDerWaalsContact O-N 3.17Å; E247-H249 PolarHBondContact O-N 3.14Å; E247-S250 WeakPolarHBondContact O-CB 3.48Å; E247-S250 PolarHBondContact O-N 2.84Å
248	R	49.8	Very low	60.8	Low	213 Å²	213	77.9 Å²	77.9	80%	0.804	44%	0.444	S	S	*	.	G	3₁₀ helix	trans	-63.3	-23.7	175.7	-76.7	179.9	-177.6	172.7	2.4	113.8	G244 S250	G244-R248 WeakPolarHBondContact O-CB 3.4Å; G244-R248 WeakPolarHBondContact O-CG 3.38Å; G244-R248 PolarHBondContact O-N 3.5Å; R248-S250 VanDerWaalsContact C-N 3.32Å
249	H	45.3	Very low	60.2	Low	129 Å²	129	81.6 Å²	81.6	60%	0.597	47%	0.469	S	S	*	.	G	3₁₀ helix	trans	-82.2	-9.3	174	-77.2	85.2	0	0	0	113.3	A245 E247 G251	A245-H249 PolarHBondContact O-ND1 3.2Å; E247-H249 PolarHBondContact O-N 3.14Å; H249-G251 VanDerWaalsContact C-N 3.28Å; H249-G251 PolarHBondContact O-N 3.19Å
250	S	45.4	Very low	59.6	Low	57 Å²	57	83.8 Å²	83.8	40%	0.399	47%	0.473	S	S	.	.	G	3₁₀ helix	trans	-84.2	3.6	-175.6	-57.2	0	0	0	0	114.1	V246 E247 R248 S252	V246-S250 PolarHBondContact O-OG 3.49Å; E247-S250 WeakPolarHBondContact O-CB 3.48Å; E247-S250 PolarHBondContact O-N 2.84Å; R248-S250 VanDerWaalsContact C-N 3.32Å; S250-S252 PolarHBondContact O-N 2.96Å; S250-S252 PolarHBondContact O-OG 3.39Å
251	G	41.8	Very low	59.4	Low	50 Å²	50	89.9 Å²	89.9	52%	0.515	49%	0.494	S	S	.	.			trans	55.5	8.3	162.8	0	0	0	0	0	117.4	H249	H249-G251 VanDerWaalsContact C-N 3.28Å; H249-G251 PolarHBondContact O-N 3.19Å
252	S	46.7	Very low	59.4	Low	92 Å²	92	91.9 Å²	91.9	64%	0.643	51%	0.511	S	S	*	.			trans	-64.9	128.3	-172.1	-63.9	0	0	0	0	108.5	S250	S250-S252 PolarHBondContact O-N 2.96Å; S250-S252 PolarHBondContact O-OG 3.39Å
253	P	42.1	Very low	59.8	Low	106 Å²	106	89 Å²	89	69%	0.688	49%	0.492	S	S	*	.			trans	-55	136	178.6	20.6	-30.2	0	0	0	108.4	L255	P253-L255 PolarHBondContact O-N 3.43Å
254	P	43.8	Very low	60.4	Low	129 Å²	129	86.9 Å²	86.9	84%	0.838	49%	0.487	S	S	*	.			trans	-60.8	106.2	178.6	23.7	-30.9	0	0	0	107.5	S256	P254-S256 PolarHBondContact O-N 3.42Å
255	L	54.1	Low	61.5	Low	116 Å²	116	91.3 Å²	91.3	61%	0.607	50%	0.502	S	S	*	.	P	Polyproline II helix	trans	-59.8	128.7	168.4	-71.3	155.9	0	0	0	106.4	P253 P412 T413	P253-L255 PolarHBondContact O-N 3.43Å; L255-P412 HydrophobicContact CD1-CB 4.42Å; L255-T413 HydrophobicContact CB-CG2 3.41Å; L255-T413 VanDerWaalsContact CB-CG2 3.41Å; L255-T413 HydrophobicContact CD1-CG2 3.67Å; L255-T413 HydrophobicContact CD2-CG2 3.87Å; L255-T413 HydrophobicContact CG-CG2 3.83Å
256	S	55.7	Low	62.7	Low	95 Å²	95	91.5 Å²	91.5	66%	0.664	50%	0.503	S	S	*	.	P	Polyproline II helix	trans	-59.6	125.4	-178.6	42.1	0	0	0	0	109.4	P254 T258	P254-S256 PolarHBondContact O-N 3.42Å; S256-T258 PolarHBondContact O-N 3.25Å
257	P	57.2	Low	64.2	Low	130 Å²	130	91.5 Å²	91.5	84%	0.844	50%	0.503	S	S	*	.	P	Polyproline II helix	trans	-62.8	124.2	178	22.9	-30.4	0	0	0	109.2
258	T	68	Low	65.9	Low	55 Å²	55	89.7 Å²	89.7	34%	0.337	51%	0.506	S	S	.	.	P	Polyproline II helix	trans	-80.7	155.5	171.5	38.8	0	0	0	0	110	S256 D263	S256-T258 PolarHBondContact O-N 3.25Å; T258-D263 WeakPolarHBondContact CB-OD1 3.45Å; T258-D263 VanDerWaalsContact OG1-CG 3.23Å; T258-D263 PolarHBondContact OG1-OD1 3.45Å; T258-D263 PolarHBondContact OG1-OD2 3.41Å; T258-D263 VanDerWaalsContact OG1-OD2 3.05Å
259	S	79.4	Confident	67.8	Low	77 Å²	77	86.3 Å²	86.3	54%	0.538	49%	0.494	S	S	.	.	P	Polyproline II helix	trans	-67.4	136.6	175.6	175.5	0	0	0	0	110.3	W261 A262 D263	S259-W261 PolarHBondContact O-N 3.18Å; S259-W261 VanDerWaalsContact O-N 3.15Å; S259-A262 WeakPolarHBondContact O-CA 3.27Å; S259-A262 VanDerWaalsContact O-CB 3.3Å; S259-A262 WeakPolarHBondContact O-CB 3.32Å; S259-A262 PolarHBondContact O-N 3.42Å; S259-D263 PolarHBondContact O-N 2.94Å
260	W	75.4	Confident	70.1	Confident	147 Å²	147	81.1 Å²	81.1	56%	0.557	47%	0.471	S	S	*	.	H	α-helix	trans	-52.5	-39.3	-179.1	-176.7	76.9	0	0	0	113.4	D263 L264	W260-D263 PolarHBondContact O-N 3.33Å; W260-L264 HydrophobicContact CH2-CD2 4.38Å; W260-L264 PolarHBondContact O-N 3.21Å
261	W	80.6	Confident	72.4	Confident	180 Å²	180	80.1 Å²	80.1	68%	0.682	46%	0.463	S	S	*	.	H	α-helix	trans	-68.3	-33.7	176.1	-73	108.7	0	0	0	113.4	S259 D263 L264 K265	S259-W261 PolarHBondContact O-N 3.18Å; S259-W261 VanDerWaalsContact O-N 3.15Å; W261-D263 VanDerWaalsContact C-N 3.35Å; W261-L264 HydrophobicContact CE3-CD2 4.44Å; W261-L264 HydrophobicContact CZ3-CD2 4.33Å; W261-K265 WeakPolarHBondContact O-CB 3.48Å; W261-K265 PolarHBondContact O-N 3.24Å; W261-K265 VanDerWaalsContact O-N 3.13Å
262	A	80.9	Confident	75	Confident	44 Å²	44	77.8 Å²	77.8	36%	0.364	44%	0.438	S	S	.	.	H	α-helix	trans	-68.1	-39.9	175.5	0	0	0	0	0	110.4	S259 K265 A266	S259-A262 WeakPolarHBondContact O-CA 3.27Å; S259-A262 VanDerWaalsContact O-CB 3.3Å; S259-A262 WeakPolarHBondContact O-CB 3.32Å; S259-A262 PolarHBondContact O-N 3.42Å; A262-K265 PolarHBondContact O-N 3.47Å; A262-A266 WeakPolarHBondContact O-CB 3.48Å; A262-A266 PolarHBondContact O-N 2.85Å
263	D	81.8	Confident	77.3	Confident	9 Å²	9	73.5 Å²	73.5	5%	0.048	41%	0.408	C	S	.	.	H	α-helix	trans	-65.3	-46.4	177.3	-64.6	-19.7	0	0	0	111.6	T258 S259 W260 W261 K265 A266 L267 R414 T417	T258-D263 WeakPolarHBondContact CB-OD1 3.45Å; T258-D263 VanDerWaalsContact OG1-CG 3.23Å; T258-D263 PolarHBondContact OG1-OD1 3.45Å; T258-D263 PolarHBondContact OG1-OD2 3.41Å; T258-D263 VanDerWaalsContact OG1-OD2 3.05Å; S259-D263 PolarHBondContact O-N 2.94Å; W260-D263 PolarHBondContact O-N 3.33Å; W261-D263 VanDerWaalsContact C-N 3.35Å; D263-K265 VanDerWaalsContact C-N 3.31Å; D263-K265 PolarHBondContact O-N 3.5Å; D263-A266 PolarHBondContact O-N 3.35Å; D263-L267 WeakPolarHBondContact O-CB 3.28Å; D263-L267 VanDerWaalsContact O-CG 3.23Å; D263-L267 WeakPolarHBondContact O-CG 3.48Å; D263-L267 PolarHBondContact O-N 2.92Å; D263-R414 HydrophobicContact CB-CG 4.23Å; D263-R414 WeakPolarHBondContact OD1-CD 3.15Å; D263-R414 WeakPolarHBondContact OD1-CG 3.38Å; D263-R414 IonicContact OD1-CZ 2.78Å; D263-R414 IonicContact OD1-NE 3.34Å; D263-R414 PolarHBondContact OD1-NE 2.95Å; D263-R414 IonicContact OD1-NH2 3.48Å; D263-T417 HydrophobicContact CB-CG2 4.49Å
264	L	84.4	Confident	79.8	Confident	50 Å²	50	70.9 Å²	70.9	26%	0.262	39%	0.39	S	S	.	.	H	α-helix	trans	-60.7	-42	178	-172.1	63.2	0	0	0	111.8	W260 W261 L267 A268 F421	W260-L264 HydrophobicContact CH2-CD2 4.38Å; W260-L264 PolarHBondContact O-N 3.21Å; W261-L264 HydrophobicContact CE3-CD2 4.44Å; W261-L264 HydrophobicContact CZ3-CD2 4.33Å; L264-L267 PolarHBondContact O-N 3.3Å; L264-A268 WeakPolarHBondContact O-CB 3.36Å; L264-A268 PolarHBondContact O-N 3.49Å; L264-F421 HydrophobicContact CD1-CD2 4.18Å; L264-F421 HydrophobicContact CD1-CE2 4.25Å
265	K	87.5	Confident	82.4	Confident	109 Å²	109	66.8 Å²	66.8	47%	0.474	36%	0.361	S	S	.	.	H	α-helix	trans	-65.5	-39.7	176.3	-174.7	177	-178.9	177.9	0	112.1	W261 A262 D263 R269	W261-K265 WeakPolarHBondContact O-CB 3.48Å; W261-K265 PolarHBondContact O-N 3.24Å; W261-K265 VanDerWaalsContact O-N 3.13Å; A262-K265 PolarHBondContact O-N 3.47Å; D263-K265 VanDerWaalsContact C-N 3.31Å; D263-K265 PolarHBondContact O-N 3.5Å; K265-R269 WeakPolarHBondContact O-CG 3.36Å; K265-R269 PolarHBondContact O-N 3.06Å
266	A	84.3	Confident	84.4	Confident	21 Å²	21	61.2 Å²	61.2	17%	0.174	33%	0.332	C	S	.	.	H	α-helix	trans	-67.7	-42	177.8	0	0	0	0	0	111.8	A262 D263 R269 N270 R414	A262-A266 WeakPolarHBondContact O-CB 3.48Å; A262-A266 PolarHBondContact O-N 2.85Å; D263-A266 PolarHBondContact O-N 3.35Å; A266-R269 PolarHBondContact O-N 2.88Å; A266-N270 PolarHBondContact O-N 3.49Å; A266-R414 VanDerWaalsContact CB-CZ 3.49Å
267	L	88.8	Confident	86.3	Confident	4 Å²	4	56.8 Å²	56.8	2%	0.021	30%	0.301	C	S	.	.	H	α-helix	trans	-63.2	-44.4	175.9	-69.1	173.6	0	0	0	111.7	D263 L264 R269 N270 F273 V410 T417 A418	D263-L267 WeakPolarHBondContact O-CB 3.28Å; D263-L267 VanDerWaalsContact O-CG 3.23Å; D263-L267 WeakPolarHBondContact O-CG 3.48Å; D263-L267 PolarHBondContact O-N 2.92Å; L264-L267 PolarHBondContact O-N 3.3Å; L267-R269 PolarHBondContact O-N 3.29Å; L267-N270 WeakPolarHBondContact O-CB 3.21Å; L267-N270 PolarHBondContact O-N 3.14Å; L267-F273 HydrophobicContact CB-CD1 3.95Å; L267-F273 HydrophobicContact CB-CE1 3.86Å; L267-F273 HydrophobicContact CD1-CE1 4.49Å; L267-F273 HydrophobicContact CD2-CD1 4.2Å; L267-F273 HydrophobicContact CD2-CE1 4.25Å; L267-F273 HydrophobicContact CD2-CG 4.42Å; L267-F273 HydrophobicContact CG-CE1 4.42Å; L267-V410 HydrophobicContact CD2-CG1 3.86Å; L267-V410 HydrophobicContact CD2-CG2 4.03Å; L267-T417 HydrophobicContact CD1-CG2 4.12Å; L267-A418 HydrophobicContact CD1-CB 3.97Å; L267-A418 HydrophobicContact CD2-CB 3.63Å; L267-A418 HydrophobicContact CG-CB 4.47Å
268	A	90.8	Very high	88.2	Confident	70 Å²	70	54.6 Å²	54.6	58%	0.579	28%	0.281	S	S	*	.	H	α-helix	trans	-64.1	-22.5	176.3	0	0	0	0	0	113.6	L264	L264-A268 WeakPolarHBondContact O-CB 3.36Å; L264-A268 PolarHBondContact O-N 3.49Å
269	R	90.7	Very high	89.6	Confident	142 Å²	142	52 Å²	52	54%	0.536	27%	0.265	S	S	.	.	T	Hydrogen-bonded Turn	trans	-88.1	-7.7	175.2	-76.5	177.8	169.4	-170.2	-7.2	113.6	K265 A266 L267 P271 P505	K265-R269 WeakPolarHBondContact O-CG 3.36Å; K265-R269 PolarHBondContact O-N 3.06Å; A266-R269 PolarHBondContact O-N 2.88Å; L267-R269 PolarHBondContact O-N 3.29Å; R269-P271 WeakPolarHBondContact O-CD 3.24Å; R269-P505 PolarHBondContact NH1-O 3Å; R269-P505 PolarHBondContact NH2-O 3.5Å; R269-P505 VanDerWaalsContact NH2-O 3.13Å
270	N	92.5	Very high	90.4	Very high	21 Å²	21	49 Å²	49	11%	0.112	24%	0.243	C	C	.	.			trans	-89.5	101.9	177.1	-177.7	-34.3	0	0	0	109.2	A266 L267 S272 F273 V274 V409 D488	A266-N270 PolarHBondContact O-N 3.49Å; L267-N270 WeakPolarHBondContact O-CB 3.21Å; L267-N270 PolarHBondContact O-N 3.14Å; N270-S272 VanDerWaalsContact C-N 3.33Å; N270-S272 PolarHBondContact O-N 3Å; N270-S272 PolarHBondContact OD1-N 2.83Å; N270-F273 HydrophobicContact CB-CB 3.91Å; N270-F273 PolarHBondContact O-N 2.9Å; N270-F273 PolarHBondContact OD1-N 3Å; N270-V274 WeakPolarHBondContact O-CG2 3.43Å; N270-V274 PolarHBondContact O-N 2.96Å; N270-V409 PolarHBondContact ND2-O 2.99Å; N270-D488 PolarHBondContact OD1-OD2 3.48Å
271	P	94.1	Very high	91.4	Very high	36 Å²	36	42.7 Å²	42.7	23%	0.234	22%	0.221	C	C	.	.	H	α-helix	trans	-63.9	-36.9	-174.2	25.5	-32.7	0	0	0	112.2	R269 F273 V274 L275 F484 D488	R269-P271 WeakPolarHBondContact O-CD 3.24Å; P271-F273 PolarHBondContact O-N 3.42Å; P271-V274 PolarHBondContact O-N 3.5Å; P271-L275 VanDerWaalsContact O-CB 3.27Å; P271-L275 WeakPolarHBondContact O-CB 3.44Å; P271-L275 VanDerWaalsContact O-CG 3.25Å; P271-L275 WeakPolarHBondContact O-CG 3.21Å; P271-L275 PolarHBondContact O-N 3.47Å; P271-F484 HydrophobicContact CB-CB 4.23Å; P271-F484 HydrophobicContact CB-CD1 4.37Å; P271-F484 HydrophobicContact CB-CD2 4.07Å; P271-F484 HydrophobicContact CB-CG 3.96Å; P271-F484 HydrophobicContact CG-CB 3.8Å; P271-F484 HydrophobicContact CG-CD1 4Å; P271-F484 HydrophobicContact CG-CD2 4.43Å; P271-F484 HydrophobicContact CG-CG 3.82Å; P271-D488 WeakPolarHBondContact CD-OD2 3.49Å; P271-D488 WeakPolarHBondContact CG-OD2 3.42Å
272	S	95.6	Very high	92.3	Very high	0 Å²	0	34.5 Å²	34.5	0%	0	19%	0.191	C	C	.	.	H	α-helix	trans	-63.9	-41.4	176.5	-65.1	0	0	0	0	112.3	N270 S276 F484 I485 D488	N270-S272 VanDerWaalsContact C-N 3.33Å; N270-S272 PolarHBondContact O-N 3Å; N270-S272 PolarHBondContact OD1-N 2.83Å; S272-S276 WeakPolarHBondContact O-CB 3.38Å; S272-S276 PolarHBondContact O-N 3.18Å; S272-S276 PolarHBondContact O-OG 3.46Å; S272-F484 VanDerWaalsContact OG-C 3.28Å; S272-F484 PolarHBondContact OG-O 3.22Å; S272-I485 VanDerWaalsContact OG-CA 3.29Å; S272-I485 WeakPolarHBondContact OG-CA 3.3Å; S272-I485 PolarHBondContact OG-N 3.15Å; S272-D488 WeakPolarHBondContact CB-OD2 3.29Å; S272-D488 PolarHBondContact N-OD2 3.18Å; S272-D488 PolarHBondContact OG-OD2 3.34Å
273	F	94.8	Very high	93	Very high	2 Å²	2	32.4 Å²	32.4	1%	0.009	17%	0.174	C	C	.	.	H	α-helix	trans	-64	-47.4	175.6	174.8	-105.3	0	0	0	111.9	L267 N270 P271 S276 S277 L406 V409 V410 A418 F421 Q422	L267-F273 HydrophobicContact CB-CD1 3.95Å; L267-F273 HydrophobicContact CB-CE1 3.86Å; L267-F273 HydrophobicContact CD1-CE1 4.49Å; L267-F273 HydrophobicContact CD2-CD1 4.2Å; L267-F273 HydrophobicContact CD2-CE1 4.25Å; L267-F273 HydrophobicContact CD2-CG 4.42Å; L267-F273 HydrophobicContact CG-CE1 4.42Å; N270-F273 HydrophobicContact CB-CB 3.91Å; N270-F273 PolarHBondContact O-N 2.9Å; N270-F273 PolarHBondContact OD1-N 3Å; P271-F273 PolarHBondContact O-N 3.42Å; F273-S276 PolarHBondContact O-OG 3.46Å; F273-S277 WeakPolarHBondContact O-CB 3.3Å; F273-S277 PolarHBondContact O-N 3.24Å; F273-S277 PolarHBondContact O-OG 3Å; F273-L406 HydrophobicContact CD2-CD1 4.42Å; F273-L406 HydrophobicContact CE2-CD1 3.92Å; F273-L406 HydrophobicContact CE2-CG 4.44Å; F273-V409 HydrophobicContact CB-CG2 4.47Å; F273-V410 HydrophobicContact CB-CG2 4.47Å; F273-V410 HydrophobicContact CD2-CG2 4.01Å; F273-V410 HydrophobicContact CG-CG2 4.39Å; F273-A418 HydrophobicContact CD2-CB 4.26Å; F273-A418 HydrophobicContact CE2-CB 3.61Å; F273-A418 HydrophobicContact CZ-CB 3.89Å; F273-A418 WeakPolarHBondContact CZ-O 3.42Å; F273-F421 AromaticContact CE1-CD1 3.93Å; F273-F421 HydrophobicContact CE1-CD1 3.93Å; F273-F421 HydrophobicContact CE1-CE1 4.46Å; F273-F421 AromaticContact CZ-CD1 3.94Å; F273-F421 HydrophobicContact CZ-CD1 3.94Å; F273-Q422 HydrophobicContact CE2-CB 4.41Å
274	V	96.4	Very high	93.7	Very high	52 Å²	52	32.2 Å²	32.2	32%	0.315	17%	0.173	S	C	.	.	H	α-helix	trans	-63.3	-49.7	-179.8	173.7	0	0	0	0	111.1	N270 P271 S277 L278	N270-V274 WeakPolarHBondContact O-CG2 3.43Å; N270-V274 PolarHBondContact O-N 2.96Å; P271-V274 PolarHBondContact O-N 3.5Å; V274-S277 PolarHBondContact O-N 3.27Å; V274-L278 HydrophobicContact CG1-CD1 4.2Å; V274-L278 WeakPolarHBondContact O-CG 3.39Å; V274-L278 PolarHBondContact O-N 3.03Å
275	L	97.3	Very high	94.4	Very high	42 Å²	42	30.6 Å²	30.6	22%	0.22	16%	0.164	C	C	.	.	H	α-helix	trans	-67.9	-40.1	-177.1	-68.7	172.1	0	0	0	112.4	P271 S277 L278 G279 T481 F484	P271-L275 VanDerWaalsContact O-CB 3.27Å; P271-L275 WeakPolarHBondContact O-CB 3.44Å; P271-L275 VanDerWaalsContact O-CG 3.25Å; P271-L275 WeakPolarHBondContact O-CG 3.21Å; P271-L275 PolarHBondContact O-N 3.47Å; L275-S277 VanDerWaalsContact C-N 3.33Å; L275-L278 PolarHBondContact O-N 3.25Å; L275-G279 PolarHBondContact O-N 2.9Å; L275-T481 VanDerWaalsContact CB-OG1 3.23Å; L275-T481 WeakPolarHBondContact CB-OG1 3.43Å; L275-F484 HydrophobicContact CD1-CD2 3.91Å; L275-F484 HydrophobicContact CD1-CE2 4.09Å
276	S	96.2	Very high	94.8	Very high	0 Å²	0	25.4 Å²	25.4	0%	0	14%	0.141	C	C	.	.	H	α-helix	trans	-67.6	-34.6	174.9	60.5	0	0	0	0	112.1	S272 F273 G279 F280 T481	S272-S276 WeakPolarHBondContact O-CB 3.38Å; S272-S276 PolarHBondContact O-N 3.18Å; S272-S276 PolarHBondContact O-OG 3.46Å; F273-S276 PolarHBondContact O-OG 3.46Å; S276-G279 PolarHBondContact O-N 3.17Å; S276-F280 WeakPolarHBondContact O-CB 3.46Å; S276-F280 PolarHBondContact O-N 2.95Å; S276-T481 PolarHBondContact N-OG1 2.84Å; S276-T481 VanDerWaalsContact N-OG1 3.13Å
277	S	96	Very high	95.3	Very high	1 Å²	1	26.5 Å²	26.5	1%	0.007	15%	0.146	C	C	.	.	H	α-helix	trans	-66.3	-40.2	173.2	-61.7	0	0	0	0	112.3	F273 V274 L275 F280 T281 Q422	F273-S277 WeakPolarHBondContact O-CB 3.3Å; F273-S277 PolarHBondContact O-N 3.24Å; F273-S277 PolarHBondContact O-OG 3Å; V274-S277 PolarHBondContact O-N 3.27Å; L275-S277 VanDerWaalsContact C-N 3.33Å; S277-F280 PolarHBondContact O-N 2.87Å; S277-T281 WeakPolarHBondContact O-CB 3.33Å; S277-T281 PolarHBondContact O-N 3.28Å; S277-T281 PolarHBondContact O-OG1 3.5Å; S277-Q422 PolarHBondContact OG-NE2 2.87Å
278	L	97.1	Very high	95.6	Very high	84 Å²	84	26.7 Å²	26.7	44%	0.44	15%	0.149	S	C	.	.	H	α-helix	trans	-65.3	-43.5	173.1	-70.1	174	0	0	0	111.8	V274 L275 F280 T281 A282 A477	V274-L278 HydrophobicContact CG1-CD1 4.2Å; V274-L278 WeakPolarHBondContact O-CG 3.39Å; V274-L278 PolarHBondContact O-N 3.03Å; L275-L278 PolarHBondContact O-N 3.25Å; L278-F280 PolarHBondContact O-N 3.14Å; L278-T281 WeakPolarHBondContact O-CB 3.4Å; L278-T281 PolarHBondContact O-N 3.46Å; L278-A282 PolarHBondContact O-N 3.19Å; L278-A477 HydrophobicContact CB-CB 4.31Å
279	G	97.3	Very high	95.8	Very high	0 Å²	0	23.3 Å²	23.3	0%	0	12%	0.121	C	C	.	.	H	α-helix	trans	-58.8	-46.5	174.7	0	0	0	0	0	112	L275 S276 T281 A282 V283	L275-G279 PolarHBondContact O-N 2.9Å; S276-G279 PolarHBondContact O-N 3.17Å; G279-T281 PolarHBondContact O-N 2.7Å; G279-A282 WeakPolarHBondContact O-CB 3.46Å; G279-A282 PolarHBondContact O-N 3.49Å; G279-V283 PolarHBondContact O-N 3.27Å; G279-V283 VanDerWaalsContact O-N 3.08Å
280	F	96.3	Very high	96	Very high	16 Å²	16	17.7 Å²	17.7	7%	0.07	10%	0.102	C	C	.	.	H	α-helix	trans	-67.6	-35.2	177.7	-173.7	-118.3	0	0	0	113.3	S276 S277 L278 A282 V283 A284 W399 V402 Q422 F478	S276-F280 WeakPolarHBondContact O-CB 3.46Å; S276-F280 PolarHBondContact O-N 2.95Å; S277-F280 PolarHBondContact O-N 2.87Å; L278-F280 PolarHBondContact O-N 3.14Å; F280-A282 VanDerWaalsContact C-N 3.27Å; F280-A282 PolarHBondContact O-N 3.39Å; F280-V283 HydrophobicContact CD2-CB 4.43Å; F280-V283 WeakPolarHBondContact O-CB 3.18Å; F280-V283 PolarHBondContact O-N 3.44Å; F280-V283 VanDerWaalsContact O-N 3.14Å; F280-A284 PolarHBondContact O-N 3.22Å; F280-W399 AromaticContact CE2-CD2 3.98Å; F280-W399 HydrophobicContact CE2-CD2 3.98Å; F280-W399 AromaticContact CE2-CE3 3.69Å; F280-W399 HydrophobicContact CE2-CE3 3.69Å; F280-W399 HydrophobicContact CE2-CH2 4.39Å; F280-W399 AromaticContact CE2-CZ3 3.92Å; F280-W399 HydrophobicContact CE2-CZ3 3.92Å; F280-W399 HydrophobicContact CZ-CD2 4.35Å; F280-W399 AromaticContact CZ-CE3 3.61Å; F280-W399 HydrophobicContact CZ-CE3 3.61Å; F280-W399 HydrophobicContact CZ-CH2 4.05Å; F280-W399 AromaticContact CZ-CZ3 3.45Å; F280-W399 HydrophobicContact CZ-CZ3 3.45Å; F280-W399 VanDerWaalsContact CZ-CZ3 3.45Å; F280-V402 HydrophobicContact CB-CG1 3.8Å; F280-V402 HydrophobicContact CB-CG2 4.29Å; F280-V402 HydrophobicContact CD1-CG1 4.39Å; F280-V402 HydrophobicContact CD2-CB 4.1Å; F280-V402 HydrophobicContact CD2-CG1 3.92Å; F280-V402 HydrophobicContact CD2-CG2 4.02Å; F280-V402 HydrophobicContact CG-CB 4.46Å; F280-V402 HydrophobicContact CG-CG1 3.79Å; F280-V402 HydrophobicContact CG-CG2 4.47Å; F280-Q422 HydrophobicContact CD1-CG 4.06Å; F280-F478 HydrophobicContact CB-CZ 4.48Å
281	T	97.3	Very high	96.1	Very high	14 Å²	14	17.2 Å²	17.2	9%	0.086	10%	0.101	C	C	.	.	H	α-helix	trans	-60.7	-39.3	172.6	-59.5	0	0	0	0	111.1	S277 L278 G279 A284 F285 L429	S277-T281 WeakPolarHBondContact O-CB 3.33Å; S277-T281 PolarHBondContact O-N 3.28Å; S277-T281 PolarHBondContact O-OG1 3.5Å; L278-T281 WeakPolarHBondContact O-CB 3.4Å; L278-T281 PolarHBondContact O-N 3.46Å; G279-T281 PolarHBondContact O-N 2.7Å; T281-A284 PolarHBondContact O-N 3.41Å; T281-F285 WeakPolarHBondContact O-CB 3.46Å; T281-F285 PolarHBondContact O-N 3.11Å; T281-L429 HydrophobicContact CG2-CB 3.69Å
282	A	97.9	Very high	96.1	Very high	8 Å²	8	15.6 Å²	15.6	7%	0.066	9%	0.09	C	C	.	.	H	α-helix	trans	-66.5	-38.1	173.3	0	0	0	0	0	112.7	L278 G279 F280 A284 F285 V286 L363 V470	L278-A282 PolarHBondContact O-N 3.19Å; G279-A282 WeakPolarHBondContact O-CB 3.46Å; G279-A282 PolarHBondContact O-N 3.49Å; F280-A282 VanDerWaalsContact C-N 3.27Å; F280-A282 PolarHBondContact O-N 3.39Å; A282-A284 VanDerWaalsContact C-N 3.35Å; A282-F285 WeakPolarHBondContact O-CB 3.43Å; A282-F285 PolarHBondContact O-N 3.12Å; A282-V286 WeakPolarHBondContact O-CG2 3.27Å; A282-V286 PolarHBondContact O-N 3.08Å; A282-L363 HydrophobicContact CB-CD2 4.26Å; A282-V470 HydrophobicContact CB-CG1 3.85Å
283	V	96.9	Very high	96.2	Very high	0 Å²	0	15.6 Å²	15.6	0%	0	9%	0.09	C	C	.	.	H	α-helix	trans	-57.6	-49	171.6	176.5	0	0	0	0	110.4	G279 F280 F285 V286 T287 L363 L395 N398 F478	G279-V283 PolarHBondContact O-N 3.27Å; G279-V283 VanDerWaalsContact O-N 3.08Å; F280-V283 HydrophobicContact CD2-CB 4.43Å; F280-V283 WeakPolarHBondContact O-CB 3.18Å; F280-V283 PolarHBondContact O-N 3.44Å; F280-V283 VanDerWaalsContact O-N 3.14Å; V283-F285 PolarHBondContact O-N 2.69Å; V283-V286 PolarHBondContact O-N 3.13Å; V283-T287 WeakPolarHBondContact O-CB 3.42Å; V283-T287 PolarHBondContact O-N 3.33Å; V283-T287 PolarHBondContact O-OG1 2.89Å; V283-L363 HydrophobicContact CG2-CD1 4.13Å; V283-L363 HydrophobicContact CG2-CD2 3.85Å; V283-L363 HydrophobicContact CG2-CG 4.49Å; V283-L395 HydrophobicContact CB-CD1 4.3Å; V283-L395 HydrophobicContact CG1-CD1 3.88Å; V283-L395 HydrophobicContact CG1-CG 4.13Å; V283-L395 HydrophobicContact CG2-CD1 4.35Å; V283-N398 HydrophobicContact CG1-CB 4.43Å; V283-N398 HydrophobicContact CG2-CB 3.89Å; V283-F478 HydrophobicContact CG2-CE2 4.12Å
284	A	96.3	Very high	96.2	Very high	4 Å²	4	15.7 Å²	15.7	3%	0.033	9%	0.091	C	C	.	.	H	α-helix	trans	-63.4	-40.5	178.4	0	0	0	0	0	112.1	F280 T281 A282 T287 G288 S426	F280-A284 PolarHBondContact O-N 3.22Å; T281-A284 PolarHBondContact O-N 3.41Å; A282-A284 VanDerWaalsContact C-N 3.35Å; A284-T287 PolarHBondContact O-N 2.96Å; A284-G288 PolarHBondContact O-N 3.37Å; A284-S426 WeakPolarHBondContact CB-O 3.19Å
285	F	97.8	Very high	96.1	Very high	16 Å²	16	13.3 Å²	13.3	7%	0.07	8%	0.077	C	C	.	.	H	α-helix	trans	-55.5	-54.6	175.2	-176	-79.4	0	0	0	111.4	T281 A282 V283 G288 S289 L429 S434 L437 L466 V470	T281-F285 WeakPolarHBondContact O-CB 3.46Å; T281-F285 PolarHBondContact O-N 3.11Å; A282-F285 WeakPolarHBondContact O-CB 3.43Å; A282-F285 PolarHBondContact O-N 3.12Å; V283-F285 PolarHBondContact O-N 2.69Å; F285-G288 PolarHBondContact O-N 3.16Å; F285-S289 PolarHBondContact O-N 3.47Å; F285-S289 VanDerWaalsContact O-N 3.09Å; F285-S289 PolarHBondContact O-OG 2.99Å; F285-L429 WeakPolarHBondContact CD2-O 3.26Å; F285-S434 WeakPolarHBondContact O-CB 3.17Å; F285-S434 PolarHBondContact O-OG 3.17Å; F285-L437 HydrophobicContact CE2-CD2 4.09Å; F285-L437 HydrophobicContact CZ-CD2 4.11Å; F285-L466 HydrophobicContact CE1-CD2 4.49Å; F285-L466 HydrophobicContact CE1-CG 4.38Å; F285-L466 HydrophobicContact CZ-CD2 3.95Å; F285-L466 HydrophobicContact CZ-CG 4.27Å; F285-V470 HydrophobicContact CB-CG1 4.02Å; F285-V470 HydrophobicContact CD1-CB 4.02Å; F285-V470 HydrophobicContact CD1-CG1 3.76Å; F285-V470 HydrophobicContact CD1-CG2 4.17Å; F285-V470 HydrophobicContact CE1-CB 4.26Å; F285-V470 HydrophobicContact CE1-CG1 4.41Å; F285-V470 HydrophobicContact CE1-CG2 3.98Å; F285-V470 HydrophobicContact CG-CG1 3.84Å; F285-V470 HydrophobicContact CZ-CG2 4.3Å
286	V	97.4	Very high	96	Very high	0 Å²	0	11.4 Å²	11.4	0%	0	7%	0.067	C	C	.	.	H	α-helix	trans	-63.6	-46	-177.9	174.3	0	0	0	0	110.3	A282 V283 S289 L290 L370 L395 C467	A282-V286 WeakPolarHBondContact O-CG2 3.27Å; A282-V286 PolarHBondContact O-N 3.08Å; V283-V286 PolarHBondContact O-N 3.13Å; V286-S289 PolarHBondContact O-N 3.24Å; V286-L290 HydrophobicContact CG1-CD1 3.77Å; V286-L290 HydrophobicContact CG1-CG 4.35Å; V286-L290 WeakPolarHBondContact O-CB 3.34Å; V286-L290 VanDerWaalsContact O-CG 3.32Å; V286-L290 WeakPolarHBondContact O-CG 3.35Å; V286-L290 PolarHBondContact O-N 3.41Å; V286-L370 HydrophobicContact CG1-CD1 3.49Å; V286-L370 VanDerWaalsContact CG1-CD1 3.49Å; V286-L395 HydrophobicContact CB-CD1 4.34Å; V286-L395 HydrophobicContact CB-CD2 4.23Å; V286-L395 HydrophobicContact CG1-CD1 4.28Å; V286-L395 HydrophobicContact CG1-CD2 3.73Å; V286-C467 HydrophobicContact CG1-CB 4.29Å; V286-C467 HydrophobicContact CG2-CB 4.15Å; V286-C467 VanDerWaalsContact CG2-O 3.3Å; V286-C467 WeakPolarHBondContact CG2-O 3.41Å
287	T	94.9	Very high	95.9	Very high	44 Å²	44	11.6 Å²	11.6	27%	0.27	7%	0.068	S	C	.	.	H	α-helix	trans	-60.8	-49.6	179.9	-52.7	0	0	0	0	111.1	V283 A284 S289 L290 A291 L395	V283-T287 WeakPolarHBondContact O-CB 3.42Å; V283-T287 PolarHBondContact O-N 3.33Å; V283-T287 PolarHBondContact O-OG1 2.89Å; A284-T287 PolarHBondContact O-N 2.96Å; T287-S289 VanDerWaalsContact C-N 3.34Å; T287-S289 PolarHBondContact O-N 2.92Å; T287-L290 PolarHBondContact O-N 3.42Å; T287-A291 WeakPolarHBondContact O-CB 3.46Å; T287-A291 PolarHBondContact O-N 3.11Å; T287-L395 VanDerWaalsContact OG1-CD2 3.31Å; T287-L395 WeakPolarHBondContact OG1-CD2 3.44Å
288	G	94	Very high	95.9	Very high	8 Å²	8	11.5 Å²	11.5	8%	0.082	7%	0.067	C	C	.	.	H	α-helix	trans	-62.5	-39.3	-179.3	0	0	0	0	0	113.2	A284 F285 L292	A284-G288 PolarHBondContact O-N 3.37Å; F285-G288 PolarHBondContact O-N 3.16Å; G288-L292 PolarHBondContact O-N 2.94Å
289	S	95.8	Very high	95.8	Very high	0 Å²	0	8.2 Å²	8.2	0%	0	5%	0.05	C	C	.	.	H	α-helix	trans	-66.5	-49.4	176.3	-77.4	0	0	0	0	112	F285 V286 T287 A291 L292 W293 S434 I438 C467	F285-S289 PolarHBondContact O-N 3.47Å; F285-S289 VanDerWaalsContact O-N 3.09Å; F285-S289 PolarHBondContact O-OG 2.99Å; V286-S289 PolarHBondContact O-N 3.24Å; T287-S289 VanDerWaalsContact C-N 3.34Å; T287-S289 PolarHBondContact O-N 2.92Å; S289-A291 VanDerWaalsContact C-N 3.28Å; S289-A291 PolarHBondContact O-N 3.45Å; S289-L292 PolarHBondContact O-N 3.41Å; S289-W293 VanDerWaalsContact O-CB 3.31Å; S289-W293 WeakPolarHBondContact O-CB 3.47Å; S289-W293 VanDerWaalsContact O-CD1 3.24Å; S289-W293 PolarHBondContact O-N 3.07Å; S289-S434 PolarHBondContact N-OG 2.92Å; S289-S434 VanDerWaalsContact N-OG 3.15Å; S289-S434 WeakPolarHBondContact OG-CB 3.48Å; S289-S434 PolarHBondContact OG-OG 3.13Å; S289-I438 WeakPolarHBondContact OG-CG1 3.35Å; S289-C467 VanDerWaalsContact CB-SG 3.51Å
290	L	95	Very high	95.6	Very high	24 Å²	24	9.6 Å²	9.6	13%	0.126	6%	0.055	C	C	.	.	H	α-helix	trans	-63.2	-37.9	178.7	-68.9	175.2	0	0	0	111.5	V286 T287 L292 W293 A294 L370	V286-L290 HydrophobicContact CG1-CD1 3.77Å; V286-L290 HydrophobicContact CG1-CG 4.35Å; V286-L290 WeakPolarHBondContact O-CB 3.34Å; V286-L290 VanDerWaalsContact O-CG 3.32Å; V286-L290 WeakPolarHBondContact O-CG 3.35Å; V286-L290 PolarHBondContact O-N 3.41Å; T287-L290 PolarHBondContact O-N 3.42Å; L290-L292 VanDerWaalsContact C-N 3.32Å; L290-L292 PolarHBondContact O-N 2.99Å; L290-W293 PolarHBondContact O-N 3.35Å; L290-A294 WeakPolarHBondContact O-CB 3.44Å; L290-A294 PolarHBondContact O-N 3.16Å; L290-L370 HydrophobicContact CD1-CD1 4.21Å; L290-L370 HydrophobicContact CD1-CD2 3.59Å; L290-L370 HydrophobicContact CD2-CD2 4.44Å
291	A	93.5	Very high	95.5	Very high	10 Å²	10	8.8 Å²	8.8	8%	0.083	5%	0.052	C	C	.	.	H	α-helix	trans	-60.4	-40.1	-178.6	0	0	0	0	0	112.9	F77 Y203 T287 S289	F77-A291 HydrophobicContact CD1-CB 4.2Å; F77-A291 HydrophobicContact CE1-CB 3.53Å; F77-A291 HydrophobicContact CZ-CB 4.28Å; Y203-A291 VanDerWaalsContact CE1-O 3.29Å; Y203-A291 WeakPolarHBondContact CE1-O 3.43Å; Y203-A291 WeakPolarHBondContact OH-CA 3.48Å; Y203-A291 VanDerWaalsContact OH-CB 3.25Å; Y203-A291 WeakPolarHBondContact OH-CB 3.4Å; Y203-A291 PolarHBondContact OH-O 3.21Å; T287-A291 WeakPolarHBondContact O-CB 3.46Å; T287-A291 PolarHBondContact O-N 3.11Å; S289-A291 VanDerWaalsContact C-N 3.28Å; S289-A291 PolarHBondContact O-N 3.45Å
292	L	95.2	Very high	95.4	Very high	2 Å²	2	9.9 Å²	9.9	1%	0.01	5%	0.054	C	C	.	.	H	α-helix	trans	-80	-45.6	175.1	-171.5	68.6	0	0	0	112.2	A80 L83 Q101 G288 S289 L290 P435	A80-L292 HydrophobicContact CB-CD1 4.18Å; L83-L292 HydrophobicContact CD1-CD1 4.29Å; L83-L292 HydrophobicContact CD2-CD1 3.77Å; L83-L292 HydrophobicContact CD2-CG 3.81Å; Q101-L292 HydrophobicContact CB-CD1 4.47Å; Q101-L292 HydrophobicContact CB-CD2 4.24Å; G288-L292 PolarHBondContact O-N 2.94Å; S289-L292 PolarHBondContact O-N 3.41Å; L290-L292 VanDerWaalsContact C-N 3.32Å; L290-L292 PolarHBondContact O-N 2.99Å; L292-P435 HydrophobicContact CB-CB 4.23Å; L292-P435 HydrophobicContact CD2-CB 3.57Å
293	W	96.6	Very high	95.1	Very high	0 Å²	0	10.6 Å²	10.6	0%	0	6%	0.058	C	C	.	.	H	α-helix	trans	-94.2	-23.1	-162.9	-68.3	114.5	0	0	0	115.2	L83 D94 S289 L290 A296 F297 P435 I438 L460 L464	L83-W293 HydrophobicContact CD2-CZ3 4.46Å; D94-W293 HydrophobicContact CB-CH2 3.47Å; D94-W293 VanDerWaalsContact CB-CH2 3.47Å; D94-W293 HydrophobicContact CB-CZ2 4.19Å; D94-W293 HydrophobicContact CB-CZ3 4.07Å; D94-W293 WeakPolarHBondContact O-CH2 3.44Å; D94-W293 WeakPolarHBondContact O-CZ2 3.18Å; S289-W293 VanDerWaalsContact O-CB 3.31Å; S289-W293 WeakPolarHBondContact O-CB 3.47Å; S289-W293 VanDerWaalsContact O-CD1 3.24Å; S289-W293 PolarHBondContact O-N 3.07Å; L290-W293 PolarHBondContact O-N 3.35Å; W293-A296 PolarHBondContact O-N 2.97Å; W293-F297 WeakPolarHBondContact O-CB 3.47Å; W293-F297 PolarHBondContact O-N 2.98Å; W293-P435 PolarHBondContact NE1-O 2.92Å; W293-I438 HydrophobicContact CD2-CG2 4.46Å; W293-I438 HydrophobicContact CG-CG2 4.18Å; W293-L460 HydrophobicContact CB-CD1 4.43Å; W293-L460 HydrophobicContact CD2-CD1 3.81Å; W293-L460 HydrophobicContact CE3-CD1 3.65Å; W293-L460 HydrophobicContact CE3-CD2 3.91Å; W293-L460 HydrophobicContact CE3-CG 4.46Å; W293-L460 HydrophobicContact CG-CD1 4.17Å; W293-L460 HydrophobicContact CZ3-CD1 4.21Å; W293-L464 HydrophobicContact CB-CD1 4.34Å; W293-L464 HydrophobicContact CB-CD2 3.92Å; W293-L464 HydrophobicContact CG-CD2 4.41Å
294	A	95.3	Very high	94.9	Very high	4 Å²	4	12.5 Å²	12.5	3%	0.033	7%	0.069	C	C	.	.	H	α-helix	trans	-62.5	-46.1	-173.2	0	0	0	0	0	113.1	L290 A296 F297 L298 F325	L290-A294 WeakPolarHBondContact O-CB 3.44Å; L290-A294 PolarHBondContact O-N 3.16Å; A294-A296 PolarHBondContact O-N 2.84Å; A294-F297 PolarHBondContact O-N 3.28Å; A294-L298 WeakPolarHBondContact O-CD1 3.44Å; A294-L298 VanDerWaalsContact O-CG 3.25Å; A294-L298 WeakPolarHBondContact O-CG 3.5Å; A294-L298 PolarHBondContact O-N 3.48Å; A294-F325 HydrophobicContact CB-CD2 3.9Å; A294-F325 HydrophobicContact CB-CE1 4.25Å; A294-F325 HydrophobicContact CB-CE2 3.41Å; A294-F325 VanDerWaalsContact CB-CE2 3.41Å; A294-F325 HydrophobicContact CB-CZ 3.61Å
295	P	94.3	Very high	94.7	Very high	2 Å²	2	15.3 Å²	15.3	1%	0.013	8%	0.083	C	C	.	.	H	α-helix	trans	-61.7	-44.7	176.5	-23.1	34.5	0	0	0	112.8	Y203 F297 L298 L299 F325	Y203-P295 HydrophobicContact CD1-CG 4.14Å; Y203-P295 HydrophobicContact CE1-CG 4.16Å; P295-F297 VanDerWaalsContact C-N 3.35Å; P295-F297 PolarHBondContact O-N 2.62Å; P295-L298 PolarHBondContact O-N 2.65Å; P295-L299 PolarHBondContact O-N 3.24Å; P295-F325 HydrophobicContact CG-CB 4.34Å; P295-F325 HydrophobicContact CG-CD1 3.73Å; P295-F325 HydrophobicContact CG-CE1 4.32Å; P295-F325 HydrophobicContact CG-CG 4.13Å
296	A	94.2	Very high	94.3	Very high	2 Å²	2	17.6 Å²	17.6	2%	0.017	11%	0.112	C	C	.	.	H	α-helix	trans	-64.6	-39	178	0	0	0	0	0	112	L83 P84 W293 A294 L299 R300	L83-A296 HydrophobicContact CD2-CB 4.34Å; P84-A296 HydrophobicContact CG-CB 4.44Å; W293-A296 PolarHBondContact O-N 2.97Å; A294-A296 PolarHBondContact O-N 2.84Å; A296-L299 PolarHBondContact O-N 3.46Å; A296-R300 WeakPolarHBondContact O-CB 3.26Å; A296-R300 VanDerWaalsContact O-CG 3.26Å; A296-R300 WeakPolarHBondContact O-CG 3.47Å; A296-R300 PolarHBondContact O-N 3.35Å
297	F	96.1	Very high	93.8	Very high	4 Å²	4	22.3 Å²	22.3	2%	0.018	13%	0.134	C	C	.	.	H	α-helix	trans	-63	-45.8	175.7	172.8	-101.9	0	0	0	112.1	W293 A294 P295 R300 S301 L374 A377 F457 L460 Q461 L464	W293-F297 WeakPolarHBondContact O-CB 3.47Å; W293-F297 PolarHBondContact O-N 2.98Å; A294-F297 PolarHBondContact O-N 3.28Å; P295-F297 VanDerWaalsContact C-N 3.35Å; P295-F297 PolarHBondContact O-N 2.62Å; F297-R300 PolarHBondContact O-N 2.93Å; F297-S301 PolarHBondContact O-N 3.42Å; F297-L374 HydrophobicContact CD1-CD2 4.27Å; F297-L374 HydrophobicContact CE1-CD2 3.73Å; F297-L374 HydrophobicContact CE2-CD2 4.12Å; F297-L374 HydrophobicContact CZ-CD2 3.64Å; F297-A377 HydrophobicContact CE1-CB 3.61Å; F297-A377 HydrophobicContact CZ-CB 3.48Å; F297-A377 VanDerWaalsContact CZ-CB 3.48Å; F297-F457 HydrophobicContact CD2-CD2 4.31Å; F297-F457 HydrophobicContact CD2-CE2 4.1Å; F297-F457 AromaticContact CE2-CD2 3.94Å; F297-F457 HydrophobicContact CE2-CD2 3.94Å; F297-F457 AromaticContact CE2-CE2 3.37Å; F297-F457 HydrophobicContact CE2-CE2 3.37Å; F297-F457 HydrophobicContact CE2-CZ 4.09Å; F297-F457 AromaticContact CZ-CE2 3.63Å; F297-F457 HydrophobicContact CZ-CE2 3.63Å; F297-F457 HydrophobicContact CZ-CZ 4.13Å; F297-L460 HydrophobicContact CB-CD2 3.9Å; F297-L460 HydrophobicContact CD2-CD2 4.3Å; F297-L460 HydrophobicContact CD2-CG 4.32Å; F297-Q461 HydrophobicContact CE2-CB 3.81Å; F297-Q461 HydrophobicContact CE2-CG 4.04Å; F297-Q461 HydrophobicContact CZ-CG 4.27Å; F297-L464 HydrophobicContact CB-CD1 4.02Å; F297-L464 HydrophobicContact CD2-CD1 3.92Å; F297-L464 HydrophobicContact CG-CD1 3.91Å
298	L	95.4	Very high	93.5	Very high	0 Å²	0	22 Å²	22	0%	0	13%	0.132	C	C	.	.	H	α-helix	trans	-60.9	-45	177.3	-71.5	164.3	0	0	0	111.2	A294 P295 S301 R302 D321 I381 T384 Y385 I388	A294-L298 WeakPolarHBondContact O-CD1 3.44Å; A294-L298 VanDerWaalsContact O-CG 3.25Å; A294-L298 WeakPolarHBondContact O-CG 3.5Å; A294-L298 PolarHBondContact O-N 3.48Å; P295-L298 PolarHBondContact O-N 2.65Å; L298-S301 WeakPolarHBondContact O-CB 3.4Å; L298-S301 PolarHBondContact O-N 3.34Å; L298-R302 PolarHBondContact O-N 3.31Å; L298-D321 HydrophobicContact CB-CB 3.87Å; L298-D321 HydrophobicContact CD1-CB 4.43Å; L298-I381 HydrophobicContact CB-CD1 4.46Å; L298-I381 HydrophobicContact CD2-CD1 3.57Å; L298-I381 HydrophobicContact CD2-CG1 4.5Å; L298-T384 HydrophobicContact CD2-CG2 3.66Å; L298-Y385 HydrophobicContact CD1-CD1 4.35Å; L298-Y385 HydrophobicContact CD1-CE1 3.51Å; L298-Y385 HydrophobicContact CD2-CE1 4.11Å; L298-Y385 HydrophobicContact CG-CE1 4.43Å; L298-I388 HydrophobicContact CD1-CD1 4.19Å; L298-I388 HydrophobicContact CD2-CD1 4.09Å; L298-I388 HydrophobicContact CG-CD1 4.43Å
299	L	93.9	Very high	93.1	Very high	14 Å²	14	29.1 Å²	29.1	7%	0.073	17%	0.167	C	C	.	.	H	α-helix	trans	-59.2	-50.8	175.2	175.3	59.7	0	0	0	111.6	P84 P295 A296 S301 R302 V303 D321	P84-L299 HydrophobicContact CB-CD2 3.55Å; P84-L299 HydrophobicContact CG-CD2 3.48Å; P84-L299 VanDerWaalsContact CG-CD2 3.48Å; P295-L299 PolarHBondContact O-N 3.24Å; A296-L299 PolarHBondContact O-N 3.46Å; L299-S301 PolarHBondContact O-N 2.94Å; L299-R302 PolarHBondContact O-N 3.37Å; L299-R302 VanDerWaalsContact O-N 3.14Å; L299-V303 HydrophobicContact CD1-CG2 4.27Å; L299-V303 WeakPolarHBondContact O-CG2 3.3Å; L299-V303 PolarHBondContact O-N 2.76Å; L299-D321 WeakPolarHBondContact CA-OD2 3.25Å; L299-D321 PolarHBondContact N-OD2 3.47Å
300	R	93.9	Very high	92.6	Very high	29 Å²	29	30.9 Å²	30.9	11%	0.109	18%	0.179	C	C	.	.	H	α-helix	trans	-58.1	-36.1	178.1	-71.2	174.8	-169.6	-170.3	4.6	111.4	E87 D94 A296 F297 V304 F457	E87-R300 IonicContact OE1-NH2 2.85Å; E87-R300 PolarHBondContact OE1-NH2 3.34Å; E87-R300 IonicContact OE2-CZ 3.85Å; E87-R300 IonicContact OE2-NH2 3.49Å; E87-R300 PolarHBondContact OE2-NH2 3.21Å; D94-R300 IonicContact OD1-CZ 2.73Å; D94-R300 IonicContact OD1-NH1 3.56Å; D94-R300 PolarHBondContact OD1-NH1 3.35Å; D94-R300 VanDerWaalsContact OD1-NH1 3.08Å; D94-R300 IonicContact OD1-NH2 2.99Å; D94-R300 PolarHBondContact OD1-NH2 3.15Å; D94-R300 IonicContact OD2-CZ 3.2Å; D94-R300 IonicContact OD2-NH1 2.83Å; D94-R300 PolarHBondContact OD2-NH1 2.99Å; D94-R300 IonicContact OD2-NH2 3.92Å; A296-R300 WeakPolarHBondContact O-CB 3.26Å; A296-R300 VanDerWaalsContact O-CG 3.26Å; A296-R300 WeakPolarHBondContact O-CG 3.47Å; A296-R300 PolarHBondContact O-N 3.35Å; F297-R300 PolarHBondContact O-N 2.93Å; R300-V304 WeakPolarHBondContact O-CG2 3.38Å; R300-V304 PolarHBondContact O-N 3.18Å; R300-F457 HydrophobicContact CB-CB 4.26Å; R300-F457 HydrophobicContact CB-CD2 4.28Å
301	S	94.8	Very high	92	Very high	0 Å²	0	31.5 Å²	31.5	0%	0	19%	0.185	C	C	.	.	H	α-helix	trans	-64.5	-46.6	175.8	-156.7	0	0	0	0	112.6	F297 L298 L299 V303 V304 L305 A377 F457	F297-S301 PolarHBondContact O-N 3.42Å; L298-S301 WeakPolarHBondContact O-CB 3.4Å; L298-S301 PolarHBondContact O-N 3.34Å; L299-S301 PolarHBondContact O-N 2.94Å; S301-V303 VanDerWaalsContact C-N 3.34Å; S301-V303 PolarHBondContact O-N 3.43Å; S301-V304 PolarHBondContact O-N 3.46Å; S301-L305 WeakPolarHBondContact O-CG 3.28Å; S301-L305 PolarHBondContact O-N 2.87Å; S301-A377 PolarHBondContact OG-O 2.89Å; S301-F457 VanDerWaalsContact CB-CE2 3.48Å; S301-F457 WeakPolarHBondContact OG-CE2 3.49Å
302	R	93.4	Very high	91.3	Very high	37 Å²	37	35.3 Å²	35.3	14%	0.14	20%	0.203	C	C	.	.	H	α-helix	trans	-64.9	-36.7	178.3	-72.4	-168	-173.5	-114.9	18.9	113.2	L298 L299 V304 L305 G306 E307 T308 D321 I381	L298-R302 PolarHBondContact O-N 3.31Å; L299-R302 PolarHBondContact O-N 3.37Å; L299-R302 VanDerWaalsContact O-N 3.14Å; R302-V304 VanDerWaalsContact C-N 3.33Å; R302-V304 PolarHBondContact O-N 3.31Å; R302-L305 PolarHBondContact O-N 2.85Å; R302-G306 PolarHBondContact O-N 3.43Å; R302-E307 HydrophobicContact CB-CB 4.23Å; R302-E307 IonicContact CZ-OE2 2.65Å; R302-E307 IonicContact NE-OE2 2.7Å; R302-E307 IonicContact NH1-OE2 3.5Å; R302-E307 PolarHBondContact NH1-OE2 3.4Å; R302-E307 PolarHBondContact O-N 3.26Å; R302-T308 HydrophobicContact CB-CG2 4.1Å; R302-T308 VanDerWaalsContact CB-OG1 3.26Å; R302-T308 WeakPolarHBondContact CB-OG1 3.42Å; R302-D321 IonicContact CZ-OD1 3.73Å; R302-D321 IonicContact NE-OD1 3.48Å; R302-D321 PolarHBondContact NE-OD1 2.9Å; R302-D321 IonicContact NE-OD2 3.17Å; R302-D321 IonicContact NH2-OD1 2.86Å; R302-D321 PolarHBondContact NH2-OD1 3.02Å; R302-I381 HydrophobicContact CG-CD1 4.09Å; R302-I381 HydrophobicContact CG-CG1 4.13Å
303	V	92.7	Very high	90	Very high	23 Å²	23	40.5 Å²	40.5	14%	0.139	24%	0.237	C	C	.	.	H	α-helix	trans	-60.9	-43.7	173.5	171.9	0	0	0	0	110.6	L299 S301 L305 G306 T308 P310 F453	L299-V303 HydrophobicContact CD1-CG2 4.27Å; L299-V303 WeakPolarHBondContact O-CG2 3.3Å; L299-V303 PolarHBondContact O-N 2.76Å; S301-V303 VanDerWaalsContact C-N 3.34Å; S301-V303 PolarHBondContact O-N 3.43Å; V303-L305 VanDerWaalsContact C-N 3.32Å; V303-L305 PolarHBondContact O-N 3.23Å; V303-G306 PolarHBondContact O-N 3.13Å; V303-G306 VanDerWaalsContact O-N 3.16Å; V303-T308 PolarHBondContact N-OG1 3.37Å; V303-P310 HydrophobicContact CG1-CB 3.88Å; V303-F453 HydrophobicContact CG1-CB 4.22Å; V303-F453 HydrophobicContact CG1-CD1 4.25Å; V303-F453 HydrophobicContact CG1-CD2 4.37Å; V303-F453 HydrophobicContact CG1-CG 4.03Å
304	V	93.1	Very high	88.5	Confident	39 Å²	39	44.4 Å²	44.4	24%	0.236	28%	0.277	C	S	.	.	H	α-helix	trans	-67.3	-32.2	176.9	170.5	0	0	0	0	112.4	R300 S301 R302 G306 F453 L454 F457	R300-V304 WeakPolarHBondContact O-CG2 3.38Å; R300-V304 PolarHBondContact O-N 3.18Å; S301-V304 PolarHBondContact O-N 3.46Å; R302-V304 VanDerWaalsContact C-N 3.33Å; R302-V304 PolarHBondContact O-N 3.31Å; V304-G306 VanDerWaalsContact C-N 3.27Å; V304-F453 HydrophobicContact CG2-CB 4.31Å; V304-L454 HydrophobicContact CG1-CD1 3.74Å; V304-F457 HydrophobicContact CG2-CB 3.82Å; V304-F457 HydrophobicContact CG2-CD1 4.48Å; V304-F457 HydrophobicContact CG2-CG 4.23Å
305	L	91.5	Very high	87.2	Confident	63 Å²	63	49.4 Å²	49.4	33%	0.33	30%	0.303	S	S	.	.	H	α-helix	trans	-74.3	-16	174.2	-77.4	170	0	0	0	113.5	S301 R302 V303 E307 R378	S301-L305 WeakPolarHBondContact O-CG 3.28Å; S301-L305 PolarHBondContact O-N 2.87Å; R302-L305 PolarHBondContact O-N 2.85Å; V303-L305 VanDerWaalsContact C-N 3.32Å; V303-L305 PolarHBondContact O-N 3.23Å; L305-E307 VanDerWaalsContact C-N 3.3Å; L305-E307 HydrophobicContact CB-CG 4.08Å; L305-R378 WeakPolarHBondContact CD2-O 3.45Å
306	G	88.4	Confident	86.1	Confident	65 Å²	65	51.9 Å²	51.9	67%	0.67	32%	0.321	S	S	*	.	T	Hydrogen-bonded Turn	trans	76	15.2	-173.5	0	0	0	0	0	114.1	R302 V303 V304	R302-G306 PolarHBondContact O-N 3.43Å; V303-G306 PolarHBondContact O-N 3.13Å; V303-G306 VanDerWaalsContact O-N 3.16Å; V304-G306 VanDerWaalsContact C-N 3.27Å
307	E	88.4	Confident	85.4	Confident	98 Å²	98	52.1 Å²	52.1	46%	0.458	32%	0.322	S	S	.	.	S	Bend	trans	-77	-28.6	176.8	-69.3	-176	-176.5	0	0	112.5	R302 L305	R302-E307 HydrophobicContact CB-CB 4.23Å; R302-E307 IonicContact CZ-OE2 2.65Å; R302-E307 IonicContact NE-OE2 2.7Å; R302-E307 IonicContact NH1-OE2 3.5Å; R302-E307 PolarHBondContact NH1-OE2 3.4Å; R302-E307 PolarHBondContact O-N 3.26Å; L305-E307 VanDerWaalsContact C-N 3.3Å; L305-E307 HydrophobicContact CB-CG 4.08Å
308	T	88.6	Confident	84.3	Confident	38 Å²	38	56 Å²	56	23%	0.233	35%	0.35	C	S	.	.	S	Bend	trans	-135.6	147.3	-178.3	56.5	0	0	0	0	110.5	R302 V303	R302-T308 HydrophobicContact CB-CG2 4.1Å; R302-T308 VanDerWaalsContact CB-OG1 3.26Å; R302-T308 WeakPolarHBondContact CB-OG1 3.42Å; V303-T308 PolarHBondContact N-OG1 3.37Å
309	L	86.1	Confident	83.4	Confident	158 Å²	158	56.6 Å²	56.6	83%	0.827	35%	0.354	S	S	*	.			trans	-67.4	145.8	174.7	-75.6	155.7	0	0	0	110.8
310	P	84	Confident	83	Confident	36 Å²	36	58.8 Å²	58.8	23%	0.234	37%	0.37	C	S	.	.			trans	-65.2	151.1	171.6	28.8	-33.7	0	0	0	110.3	V303 L312 F453	V303-P310 HydrophobicContact CG1-CB 3.88Å; P310-L312 HydrophobicContact CG-CD2 4.42Å; P310-L312 PolarHBondContact O-N 3.45Å; P310-L312 VanDerWaalsContact O-N 3.17Å; P310-F453 HydrophobicContact CB-CD1 4.45Å; P310-F453 HydrophobicContact CB-CE1 3.71Å; P310-F453 HydrophobicContact CB-CE2 4.01Å; P310-F453 HydrophobicContact CB-CZ 3.45Å; P310-F453 VanDerWaalsContact CB-CZ 3.45Å; P310-F453 HydrophobicContact CG-CE2 4.13Å; P310-F453 HydrophobicContact CG-CZ 3.89Å
311	C	82.5	Confident	82.9	Confident	38 Å²	38	57.4 Å²	57.4	26%	0.257	37%	0.365	S	S	.	.			trans	-63.2	115.7	167.9	-65.4	0	0	0	0	109.6	Q88 C317	Q88-C311 PolarHBondContact NE2-O 2.97Å; C311-C317 HydrophobicContact CB-CB 4.34Å; C311-C317 WeakPolarHBondContact CB-SG 3.3Å; C311-C317 WeakPolarHBondContact SG-CB 3.17Å; C311-C317 CovalentContact SG-SG 2.02Å; C311-C317 PolarHBondContact SG-SG 3.26Å
312	L	78.8	Confident	82.8	Confident	89 Å²	89	57.8 Å²	57.8	47%	0.466	37%	0.368	S	S	.	.			trans	-106.3	142.1	175.6	-66.9	178.9	0	0	0	112.1	Q88 P310 G314 D315	Q88-L312 PolarHBondContact NE2-O 3.38Å; P310-L312 HydrophobicContact CG-CD2 4.42Å; P310-L312 PolarHBondContact O-N 3.45Å; P310-L312 VanDerWaalsContact O-N 3.17Å; L312-G314 PolarHBondContact O-N 3.06Å; L312-G314 VanDerWaalsContact O-N 3.09Å; L312-D315 PolarHBondContact O-N 3.28Å
313	P	68.6	Low	82.8	Confident	112 Å²	112	58.6 Å²	58.6	73%	0.727	38%	0.375	S	S	*	.	T	Hydrogen-bonded Turn	trans	-58.4	118.1	-171.6	-24	32.9	0	0	0	111.4	Q88	Q88-P313 VanDerWaalsContact NE2-N 3.11Å
314	G	64.9	Low	82.9	Confident	82 Å²	82	59.9 Å²	59.9	85%	0.845	38%	0.38	S	S	*	.	T	Hydrogen-bonded Turn	trans	106.4	-11.3	-178.6	0	0	0	0	0	114.8	L312	L312-G314 PolarHBondContact O-N 3.06Å; L312-G314 VanDerWaalsContact O-N 3.09Å
315	D	68.1	Low	83	Confident	108 Å²	108	58.2 Å²	58.2	58%	0.578	37%	0.37	S	S	*	.	S	Bend	trans	-101.5	145.8	174	-68.7	-28	0	0	0	111.3	Q88 L312	Q88-D315 PolarHBondContact OE1-O 3.23Å; L312-D315 PolarHBondContact O-N 3.28Å
316	S	71.8	Confident	83.1	Confident	54 Å²	54	55.2 Å²	55.2	38%	0.378	35%	0.354	S	S	.	.			trans	-74	129.4	171.4	60.5	0	0	0	0	110.8	S318	S316-S318 PolarHBondContact O-N 3.48Å
317	C	79.1	Confident	83.5	Confident	8 Å²	8	56.2 Å²	56.2	5%	0.054	34%	0.344	C	S	.	.			trans	-72.7	82	178.3	-64.5	0	0	0	0	111.7	P84 D85 K210 C311 S319	P84-C317 HydrophobicContact CB-CB 4.35Å; D85-C317 WeakPolarHBondContact OD1-CB 3.38Å; D85-C317 PolarHBondContact OD1-N 3.31Å; K210-C317 VanDerWaalsContact CE-O 3.26Å; K210-C317 WeakPolarHBondContact CE-O 3.49Å; K210-C317 PolarHBondContact NZ-O 3.5Å; C311-C317 HydrophobicContact CB-CB 4.34Å; C311-C317 WeakPolarHBondContact CB-SG 3.3Å; C311-C317 WeakPolarHBondContact SG-CB 3.17Å; C311-C317 CovalentContact SG-SG 2.02Å; C311-C317 PolarHBondContact SG-SG 3.26Å; C317-S319 PolarHBondContact O-N 2.94Å
318	S	71.9	Confident	83.9	Confident	86 Å²	86	52.3 Å²	52.3	60%	0.601	33%	0.326	S	S	*	.			trans	-72.9	113.7	176.5	172.7	0	0	0	0	111.1	S316	S316-S318 PolarHBondContact O-N 3.48Å
319	S	76.4	Confident	84.1	Confident	11 Å²	11	51.1 Å²	51.1	8%	0.077	32%	0.319	C	S	.	.			trans	-142.3	138.5	169.7	176.2	0	0	0	0	111.9	S207 C317 D321	S207-S319 PolarHBondContact OG-O 2.87Å; C317-S319 PolarHBondContact O-N 2.94Å; S319-D321 PolarHBondContact O-N 3.27Å; S319-D321 WeakPolarHBondContact OG-CB 3.3Å; S319-D321 PolarHBondContact OG-N 3.44Å; S319-D321 PolarHBondContact OG-OD2 3.07Å
320	S	85.4	Confident	84.5	Confident	60 Å²	60	44.7 Å²	44.7	42%	0.42	29%	0.287	S	S	.	.	S	Bend	trans	-77.4	-5.1	172.1	56.4	0	0	0	0	113.4	S322 L323 I324	S320-S322 PolarHBondContact O-N 2.94Å; S320-L323 WeakPolarHBondContact O-CB 3.46Å; S320-L323 PolarHBondContact O-N 3.36Å; S320-L323 VanDerWaalsContact O-N 3.16Å; S320-I324 WeakPolarHBondContact O-CG1 3.24Å; S320-I324 PolarHBondContact O-N 3.36Å
321	D	92	Very high	85	Confident	1 Å²	1	47.7 Å²	47.7	1%	0.005	30%	0.3	C	S	.	.	H	α-helix	trans	-65.9	-39.7	-172.9	-61	-43.2	0	0	0	112.5	L298 L299 R302 S319 L323 I324 F325 Y385	L298-D321 HydrophobicContact CB-CB 3.87Å; L298-D321 HydrophobicContact CD1-CB 4.43Å; L299-D321 WeakPolarHBondContact CA-OD2 3.25Å; L299-D321 PolarHBondContact N-OD2 3.47Å; R302-D321 IonicContact CZ-OD1 3.73Å; R302-D321 IonicContact NE-OD1 3.48Å; R302-D321 PolarHBondContact NE-OD1 2.9Å; R302-D321 IonicContact NE-OD2 3.17Å; R302-D321 IonicContact NH2-OD1 2.86Å; R302-D321 PolarHBondContact NH2-OD1 3.02Å; S319-D321 PolarHBondContact O-N 3.27Å; S319-D321 WeakPolarHBondContact OG-CB 3.3Å; S319-D321 PolarHBondContact OG-N 3.44Å; S319-D321 PolarHBondContact OG-OD2 3.07Å; D321-L323 VanDerWaalsContact C-N 3.34Å; D321-L323 PolarHBondContact O-N 3.4Å; D321-I324 PolarHBondContact O-N 3.33Å; D321-F325 WeakPolarHBondContact O-CB 3.49Å; D321-F325 PolarHBondContact O-N 3.11Å; D321-Y385 WeakPolarHBondContact CA-OH 3.25Å; D321-Y385 WeakPolarHBondContact CB-OH 3.37Å; D321-Y385 PolarHBondContact OD1-OH 3.09Å
322	S	92.8	Very high	85.6	Confident	7 Å²	7	45.9 Å²	45.9	5%	0.049	29%	0.288	C	S	.	.	H	α-helix	trans	-63	-39.4	173.1	-64.9	0	0	0	0	112.1	G81 Y203 S320 G326	G81-S322 PolarHBondContact O-OG 3.13Å; Y203-S322 VanDerWaalsContact CB-O 3.24Å; Y203-S322 WeakPolarHBondContact CB-O 3.36Å; S320-S322 PolarHBondContact O-N 2.94Å; S322-G326 PolarHBondContact O-N 3.5Å
323	L	93.4	Very high	86.2	Confident	54 Å²	54	42 Å²	42	28%	0.283	27%	0.269	S	S	.	.	H	α-helix	trans	-65.6	-48.7	176.9	-177.4	159	0	0	0	110.9	I204 S320 D321 G326 L327	I204-L323 HydrophobicContact CG1-CG 4.46Å; S320-L323 WeakPolarHBondContact O-CB 3.46Å; S320-L323 PolarHBondContact O-N 3.36Å; S320-L323 VanDerWaalsContact O-N 3.16Å; D321-L323 VanDerWaalsContact C-N 3.34Å; D321-L323 PolarHBondContact O-N 3.4Å; L323-G326 PolarHBondContact O-N 3.44Å; L323-L327 HydrophobicContact CD2-CD1 3.71Å; L323-L327 HydrophobicContact CD2-CG 4.29Å; L323-L327 WeakPolarHBondContact O-CG 3.5Å; L323-L327 PolarHBondContact O-N 2.58Å
324	I	95	Very high	87.3	Confident	50 Å²	50	39.1 Å²	39.1	26%	0.256	25%	0.249	S	C	.	.	H	α-helix	trans	-64.4	-44.7	-179.5	-64.2	165.5	0	0	0	110.2	S320 D321 G326 L327 I328 Y385	S320-I324 WeakPolarHBondContact O-CG1 3.24Å; S320-I324 PolarHBondContact O-N 3.36Å; D321-I324 PolarHBondContact O-N 3.33Å; I324-G326 VanDerWaalsContact C-N 3.34Å; I324-G326 PolarHBondContact O-N 3.35Å; I324-L327 PolarHBondContact O-N 3.33Å; I324-I328 HydrophobicContact CG2-CD1 3.91Å; I324-I328 WeakPolarHBondContact O-CG1 3.38Å; I324-I328 PolarHBondContact O-N 2.89Å; I324-Y385 HydrophobicContact CB-CE1 4Å; I324-Y385 HydrophobicContact CD1-CE2 4.23Å; I324-Y385 HydrophobicContact CG2-CD1 3.7Å; I324-Y385 HydrophobicContact CG2-CD2 4.44Å; I324-Y385 HydrophobicContact CG2-CE1 3.41Å; I324-Y385 VanDerWaalsContact CG2-CE1 3.41Å; I324-Y385 HydrophobicContact CG2-CE2 4.23Å; I324-Y385 HydrophobicContact CG2-CG 4.21Å
325	F	95.5	Very high	88.7	Confident	4 Å²	4	39.1 Å²	39.1	2%	0.018	23%	0.23	C	C	.	.	H	α-helix	trans	-60.9	-43.2	175.8	-173.9	-102.8	0	0	0	111.4	Y203 A294 P295 D321 L327 I328 T329 I388	Y203-F325 HydrophobicContact CD1-CD1 4.38Å; Y203-F325 HydrophobicContact CD2-CD1 4.11Å; Y203-F325 HydrophobicContact CD2-CE1 4.46Å; Y203-F325 HydrophobicContact CE1-CD1 4.2Å; Y203-F325 HydrophobicContact CE1-CE1 4.22Å; Y203-F325 AromaticContact CE2-CD1 3.93Å; Y203-F325 HydrophobicContact CE2-CD1 3.93Å; Y203-F325 AromaticContact CE2-CE1 3.83Å; Y203-F325 HydrophobicContact CE2-CE1 3.83Å; Y203-F325 HydrophobicContact CG-CD1 4.34Å; Y203-F325 AromaticContact CZ-CD1 3.99Å; Y203-F325 AromaticContact CZ-CE1 3.7Å; A294-F325 HydrophobicContact CB-CD2 3.9Å; A294-F325 HydrophobicContact CB-CE1 4.25Å; A294-F325 HydrophobicContact CB-CE2 3.41Å; A294-F325 VanDerWaalsContact CB-CE2 3.41Å; A294-F325 HydrophobicContact CB-CZ 3.61Å; P295-F325 HydrophobicContact CG-CB 4.34Å; P295-F325 HydrophobicContact CG-CD1 3.73Å; P295-F325 HydrophobicContact CG-CE1 4.32Å; P295-F325 HydrophobicContact CG-CG 4.13Å; D321-F325 WeakPolarHBondContact O-CB 3.49Å; D321-F325 PolarHBondContact O-N 3.11Å; F325-L327 VanDerWaalsContact C-N 3.34Å; F325-L327 PolarHBondContact O-N 2.92Å; F325-I328 WeakPolarHBondContact O-CB 3.16Å; F325-I328 PolarHBondContact O-N 2.92Å; F325-I328 VanDerWaalsContact O-N 3.14Å; F325-T329 PolarHBondContact O-N 2.65Å; F325-T329 PolarHBondContact O-OG1 2.75Å; F325-I388 HydrophobicContact CD2-CG2 4.17Å; F325-I388 HydrophobicContact CE2-CG2 3.87Å
326	G	94.1	Very high	89.9	Confident	0 Å²	0	34 Å²	34	0%	0	20%	0.202	C	C	.	.	H	α-helix	trans	-60.7	-39.3	175.3	0	0	0	0	0	113.9	G200 S322 L323 I324 C330	G200-G326 WeakPolarHBondContact CA-O 3.42Å; S322-G326 PolarHBondContact O-N 3.5Å; L323-G326 PolarHBondContact O-N 3.44Å; I324-G326 VanDerWaalsContact C-N 3.34Å; I324-G326 PolarHBondContact O-N 3.35Å; G326-C330 PolarHBondContact O-N 3.42Å
327	L	95.8	Very high	90.9	Very high	87 Å²	87	33.9 Å²	33.9	46%	0.455	20%	0.199	S	C	.	.	H	α-helix	trans	-64.8	-42.9	172.8	-71.3	175.4	0	0	0	112	I204 L323 I324 F325 C330 L331	I204-L327 HydrophobicContact CD1-CD2 3.88Å; I204-L327 HydrophobicContact CD1-CG 4.16Å; L323-L327 HydrophobicContact CD2-CD1 3.71Å; L323-L327 HydrophobicContact CD2-CG 4.29Å; L323-L327 WeakPolarHBondContact O-CG 3.5Å; L323-L327 PolarHBondContact O-N 2.58Å; I324-L327 PolarHBondContact O-N 3.33Å; F325-L327 VanDerWaalsContact C-N 3.34Å; F325-L327 PolarHBondContact O-N 2.92Å; L327-C330 PolarHBondContact O-N 3.09Å; L327-L331 WeakPolarHBondContact O-CG 3.5Å; L327-L331 PolarHBondContact O-N 2.85Å; L327-L331 VanDerWaalsContact O-N 3.12Å
328	I	96.3	Very high	91.5	Very high	16 Å²	16	35.5 Å²	35.5	8%	0.082	22%	0.217	C	C	.	.	H	α-helix	trans	-59.6	-53.9	175.8	-70.5	166.5	0	0	0	109.2	I324 F325 C330 L331 T332 Y385 I388 F389 E392	I324-I328 HydrophobicContact CG2-CD1 3.91Å; I324-I328 WeakPolarHBondContact O-CG1 3.38Å; I324-I328 PolarHBondContact O-N 2.89Å; F325-I328 WeakPolarHBondContact O-CB 3.16Å; F325-I328 PolarHBondContact O-N 2.92Å; F325-I328 VanDerWaalsContact O-N 3.14Å; I328-C330 VanDerWaalsContact C-N 3.32Å; I328-C330 PolarHBondContact O-N 3.4Å; I328-L331 PolarHBondContact O-N 3.02Å; I328-T332 HydrophobicContact CG2-CG2 3.67Å; I328-T332 WeakPolarHBondContact O-CB 3.5Å; I328-T332 VanDerWaalsContact O-CG2 3.26Å; I328-T332 WeakPolarHBondContact O-CG2 3.13Å; I328-T332 PolarHBondContact O-N 3.04Å; I328-T332 PolarHBondContact O-OG1 2.96Å; I328-Y385 HydrophobicContact CD1-CD1 3.53Å; I328-Y385 HydrophobicContact CD1-CE1 4.27Å; I328-Y385 HydrophobicContact CD1-CG 4.29Å; I328-I388 HydrophobicContact CG2-CG2 4.18Å; I328-F389 HydrophobicContact CG2-CB 4.09Å; I328-F389 HydrophobicContact CG2-CD2 4.08Å; I328-E392 WeakPolarHBondContact CG2-OE2 3.48Å
329	T	94.4	Very high	92.6	Very high	13 Å²	13	35.5 Å²	35.5	8%	0.08	21%	0.21	C	C	.	.	H	α-helix	trans	-56	-41.2	179.6	-63.8	0	0	0	0	113.4	Y203 F325 T332 G333 E392	Y203-T329 HydrophobicContact CE2-CG2 4.49Å; F325-T329 PolarHBondContact O-N 2.65Å; F325-T329 PolarHBondContact O-OG1 2.75Å; T329-T332 WeakPolarHBondContact CA-OG1 3.2Å; T329-T332 PolarHBondContact O-OG1 3.15Å; T329-G333 PolarHBondContact O-N 2.79Å; T329-E392 WeakPolarHBondContact CA-OE1 3.31Å; T329-E392 WeakPolarHBondContact CA-OE2 3.37Å; T329-E392 WeakPolarHBondContact CB-OE1 3.31Å; T329-E392 WeakPolarHBondContact CG2-OE1 3.41Å; T329-E392 PolarHBondContact OG1-OE1 3.41Å
330	C	92.9	Very high	93.4	Very high	23 Å²	23	35 Å²	35	16%	0.155	21%	0.206	C	C	.	.	H	α-helix	trans	-58.2	-51.1	173.4	-86.2	0	0	0	0	111.6	V197 G200 G326 L327 I328 V334	V197-C330 PolarHBondContact O-SG 3.37Å; G200-C330 VanDerWaalsContact CA-SG 3.52Å; G326-C330 PolarHBondContact O-N 3.42Å; L327-C330 PolarHBondContact O-N 3.09Å; I328-C330 VanDerWaalsContact C-N 3.32Å; I328-C330 PolarHBondContact O-N 3.4Å; C330-V334 WeakPolarHBondContact O-CG2 3.47Å; C330-V334 PolarHBondContact O-N 3.43Å
331	L	95.4	Very high	93.7	Very high	98 Å²	98	34.8 Å²	34.8	51%	0.513	20%	0.203	S	C	.	.	H	α-helix	trans	-70.2	-46.6	-175.1	-68.3	173.3	0	0	0	111.7	L327 I328 V334 L335 F389	L327-L331 WeakPolarHBondContact O-CG 3.5Å; L327-L331 PolarHBondContact O-N 2.85Å; L327-L331 VanDerWaalsContact O-N 3.12Å; I328-L331 PolarHBondContact O-N 3.02Å; L331-V334 PolarHBondContact O-N 2.95Å; L331-L335 VanDerWaalsContact O-CB 3.24Å; L331-L335 WeakPolarHBondContact O-CB 3.31Å; L331-L335 WeakPolarHBondContact O-CG 3.46Å; L331-L335 PolarHBondContact O-N 3.5Å; L331-F389 HydrophobicContact CB-CE2 4.17Å
332	T	95	Very high	93.7	Very high	0 Å²	0	37.1 Å²	37.1	0%	0	21%	0.214	C	C	.	.	H	α-helix	trans	-68.2	-35.9	-177.3	58.6	0	0	0	0	111.8	I328 T329 G336 F389 E392 T393	I328-T332 HydrophobicContact CG2-CG2 3.67Å; I328-T332 WeakPolarHBondContact O-CB 3.5Å; I328-T332 VanDerWaalsContact O-CG2 3.26Å; I328-T332 WeakPolarHBondContact O-CG2 3.13Å; I328-T332 PolarHBondContact O-N 3.04Å; I328-T332 PolarHBondContact O-OG1 2.96Å; T329-T332 WeakPolarHBondContact CA-OG1 3.2Å; T329-T332 PolarHBondContact O-OG1 3.15Å; T332-G336 VanDerWaalsContact O-CA 3.31Å; T332-G336 WeakPolarHBondContact O-CA 3.39Å; T332-G336 PolarHBondContact O-N 2.86Å; T332-F389 HydrophobicContact CG2-CB 4.4Å; T332-F389 HydrophobicContact CG2-CD2 3.46Å; T332-F389 VanDerWaalsContact CG2-CD2 3.46Å; T332-F389 HydrophobicContact CG2-CE2 3.76Å; T332-F389 HydrophobicContact CG2-CG 3.95Å; T332-F389 HydrophobicContact CG2-CZ 4.46Å; T332-F389 VanDerWaalsContact CG2-O 3.29Å; T332-F389 WeakPolarHBondContact CG2-O 3.43Å; T332-E392 HydrophobicContact CG2-CB 4.2Å; T332-E392 WeakPolarHBondContact OG1-CG 3.39Å; T332-E392 PolarHBondContact OG1-OE2 2.89Å; T332-T393 WeakPolarHBondContact CG2-OG1 3.46Å
333	G	91.4	Very high	93.9	Very high	7 Å²	7	39.9 Å²	39.9	7%	0.072	23%	0.227	C	C	.	.	H	α-helix	trans	-62.1	-48.3	174.1	0	0	0	0	0	112.2	T329 V337	T329-G333 PolarHBondContact O-N 2.79Å; G333-V337 WeakPolarHBondContact O-CB 3.12Å; G333-V337 VanDerWaalsContact O-CG2 3.25Å; G333-V337 WeakPolarHBondContact O-CG2 3.41Å; G333-V337 PolarHBondContact O-N 3.38Å
334	V	91.2	Very high	93.9	Very high	52 Å²	52	37.4 Å²	37.4	32%	0.315	21%	0.214	S	C	.	.	H	α-helix	trans	-66.8	-50.6	178.6	172.5	0	0	0	0	111.6	F193 V197 C330 L331 G338	F193-V334 HydrophobicContact CE1-CG2 3.99Å; F193-V334 HydrophobicContact CE2-CB 4.17Å; F193-V334 HydrophobicContact CE2-CG1 3.81Å; F193-V334 HydrophobicContact CE2-CG2 3.67Å; F193-V334 HydrophobicContact CZ-CB 4Å; F193-V334 HydrophobicContact CZ-CG1 3.57Å; F193-V334 HydrophobicContact CZ-CG2 3.27Å; V197-V334 HydrophobicContact CG2-CG2 4.44Å; C330-V334 WeakPolarHBondContact O-CG2 3.47Å; C330-V334 PolarHBondContact O-N 3.43Å; L331-V334 PolarHBondContact O-N 2.95Å; V334-G338 PolarHBondContact O-N 2.73Å; V334-G338 VanDerWaalsContact O-N 3.16Å
335	L	94.6	Very high	93.8	Very high	83 Å²	83	41.1 Å²	41.1	44%	0.435	23%	0.225	S	C	.	.	H	α-helix	trans	-65.3	-45.8	-178.3	-69.8	172.5	0	0	0	111.2	L331 G338 L339 F389	L331-L335 VanDerWaalsContact O-CB 3.24Å; L331-L335 WeakPolarHBondContact O-CB 3.31Å; L331-L335 WeakPolarHBondContact O-CG 3.46Å; L331-L335 PolarHBondContact O-N 3.5Å; L335-G338 PolarHBondContact O-N 3.43Å; L335-L339 VanDerWaalsContact O-CB 3.25Å; L335-L339 WeakPolarHBondContact O-CB 3.3Å; L335-L339 WeakPolarHBondContact O-CG 3.47Å; L335-L339 PolarHBondContact O-N 2.96Å; L335-F389 HydrophobicContact CD1-CZ 3.98Å
336	G	94.3	Very high	93.8	Very high	0 Å²	0	48.1 Å²	48.1	0%	0	25%	0.251	C	S	.	.	H	α-helix	trans	-62.8	-50.4	-177.3	0	0	0	0	0	112.2	T332 G338 L339 G340 T393 M397	T332-G336 VanDerWaalsContact O-CA 3.31Å; T332-G336 WeakPolarHBondContact O-CA 3.39Å; T332-G336 PolarHBondContact O-N 2.86Å; G336-G338 VanDerWaalsContact C-N 3.35Å; G336-G338 PolarHBondContact O-N 3.29Å; G336-L339 PolarHBondContact O-N 3.42Å; G336-G340 PolarHBondContact O-N 3.31Å; G336-T393 WeakPolarHBondContact CA-O 3.36Å; G336-M397 VanDerWaalsContact O-CA 3.29Å; G336-M397 WeakPolarHBondContact O-CA 3.3Å; G336-M397 VanDerWaalsContact O-CG 3.27Å; G336-M397 WeakPolarHBondContact O-CG 3.21Å
337	V	91.8	Very high	93.8	Very high	51 Å²	51	52 Å²	52	31%	0.309	27%	0.272	S	S	.	.	H	α-helix	trans	-60.5	-45.7	177.8	174.1	0	0	0	0	110.9	G333 G340 V341 S396 W399 A400	G333-V337 WeakPolarHBondContact O-CB 3.12Å; G333-V337 VanDerWaalsContact O-CG2 3.25Å; G333-V337 WeakPolarHBondContact O-CG2 3.41Å; G333-V337 PolarHBondContact O-N 3.38Å; V337-G340 PolarHBondContact O-N 3.25Å; V337-V341 WeakPolarHBondContact O-CG2 3.43Å; V337-V341 PolarHBondContact O-N 3.12Å; V337-V341 VanDerWaalsContact O-N 3.09Å; V337-S396 WeakPolarHBondContact CG2-O 3.29Å; V337-W399 HydrophobicContact CG2-CB 4.39Å; V337-A400 HydrophobicContact CG1-CB 4.09Å
338	G	91.3	Very high	93.6	Very high	42 Å²	42	51.7 Å²	51.7	43%	0.433	26%	0.264	S	S	.	.	H	α-helix	trans	-62.4	-46.4	178.9	0	0	0	0	0	113.2	V334 L335 G336 E342	V334-G338 PolarHBondContact O-N 2.73Å; V334-G338 VanDerWaalsContact O-N 3.16Å; L335-G338 PolarHBondContact O-N 3.43Å; G336-G338 VanDerWaalsContact C-N 3.35Å; G336-G338 PolarHBondContact O-N 3.29Å; G338-E342 WeakPolarHBondContact O-CB 3.04Å; G338-E342 PolarHBondContact O-N 3.5Å
339	L	95	Very high	93.4	Very high	86 Å²	86	60 Å²	60	45%	0.45	29%	0.294	S	S	.	.	H	α-helix	trans	-62.5	-44.1	176.4	-73.8	172.7	0	0	0	111.4	L335 G336 E342 I343 T393	L335-L339 VanDerWaalsContact O-CB 3.25Å; L335-L339 WeakPolarHBondContact O-CB 3.3Å; L335-L339 WeakPolarHBondContact O-CG 3.47Å; L335-L339 PolarHBondContact O-N 2.96Å; G336-L339 PolarHBondContact O-N 3.42Å; L339-E342 PolarHBondContact O-N 2.99Å; L339-I343 HydrophobicContact CB-CD1 4.38Å; L339-I343 VanDerWaalsContact O-CB 3.29Å; L339-I343 WeakPolarHBondContact O-CB 3.19Å; L339-I343 WeakPolarHBondContact O-CD1 3.45Å; L339-I343 WeakPolarHBondContact O-CG1 3.34Å; L339-I343 PolarHBondContact O-N 3.3Å; L339-T393 HydrophobicContact CD1-CG2 4.18Å
340	G	93.5	Very high	93.3	Very high	0 Å²	0	67.9 Å²	67.9	0%	0	33%	0.328	C	S	.	.	H	α-helix	trans	-55.1	-55.5	177.3	0	0	0	0	0	111.6	G336 V337 E342 I343 S344 I401	G336-G340 PolarHBondContact O-N 3.31Å; V337-G340 PolarHBondContact O-N 3.25Å; G340-E342 PolarHBondContact O-N 2.98Å; G340-I343 PolarHBondContact O-N 3.03Å; G340-S344 WeakPolarHBondContact O-CB 3.29Å; G340-S344 PolarHBondContact O-N 3.04Å; G340-I401 WeakPolarHBondContact O-CD1 3.45Å
341	V	91.4	Very high	93.3	Very high	57 Å²	57	69.5 Å²	69.5	35%	0.345	34%	0.335	S	S	.	.	H	α-helix	trans	-59.6	-44.8	-179.9	174	0	0	0	0	111.7	V337 S344 R345 A400	V337-V341 WeakPolarHBondContact O-CG2 3.43Å; V337-V341 PolarHBondContact O-N 3.12Å; V337-V341 VanDerWaalsContact O-N 3.09Å; V341-S344 PolarHBondContact O-N 3.42Å; V341-R345 VanDerWaalsContact O-CB 3.25Å; V341-R345 WeakPolarHBondContact O-CB 3.34Å; V341-R345 PolarHBondContact O-N 2.92Å; V341-A400 HydrophobicContact CG2-CB 3.49Å; V341-A400 VanDerWaalsContact CG2-CB 3.49Å
342	E	93.7	Very high	93.1	Very high	50 Å²	50	68 Å²	68	23%	0.234	33%	0.331	C	S	.	.	H	α-helix	trans	-69.1	-43.3	-176.8	-179.1	59	-173.1	0	0	112.7	G338 L339 G340 S344 R345 R346	G338-E342 WeakPolarHBondContact O-CB 3.04Å; G338-E342 PolarHBondContact O-N 3.5Å; L339-E342 PolarHBondContact O-N 2.99Å; G340-E342 PolarHBondContact O-N 2.98Å; E342-S344 VanDerWaalsContact C-N 3.34Å; E342-R345 VanDerWaalsContact CD-NH2 3.29Å; E342-R345 PolarHBondContact O-N 2.82Å; E342-R345 IonicContact OE1-NH2 3.7Å; E342-R345 PolarHBondContact OE1-NH2 3.29Å; E342-R345 VanDerWaalsContact OE1-NH2 3.11Å; E342-R345 IonicContact OE2-CZ 3.65Å; E342-R345 IonicContact OE2-NE 3.92Å; E342-R345 PolarHBondContact OE2-NE 3.39Å; E342-R345 IonicContact OE2-NH2 2.83Å; E342-R345 PolarHBondContact OE2-NH2 3.24Å; E342-R346 WeakPolarHBondContact O-CG 3.35Å; E342-R346 PolarHBondContact O-N 3.38Å; E342-R346 IonicContact OE1-CZ 3.22Å; E342-R346 IonicContact OE1-NE 3.46Å; E342-R346 PolarHBondContact OE1-NE 3.24Å; E342-R346 IonicContact OE1-NH2 3.51Å; E342-R346 PolarHBondContact OE1-NH2 3.43Å
343	I	95.9	Very high	93	Very high	65 Å²	65	72.3 Å²	72.3	33%	0.333	35%	0.348	S	S	.	.	H	α-helix	trans	-61.4	-47.1	175.8	-68.4	167.3	0	0	0	109.4	L339 G340 R345 R346 L347 V358 M397	L339-I343 HydrophobicContact CB-CD1 4.38Å; L339-I343 VanDerWaalsContact O-CB 3.29Å; L339-I343 WeakPolarHBondContact O-CB 3.19Å; L339-I343 WeakPolarHBondContact O-CD1 3.45Å; L339-I343 WeakPolarHBondContact O-CG1 3.34Å; L339-I343 PolarHBondContact O-N 3.3Å; G340-I343 PolarHBondContact O-N 3.03Å; I343-R345 PolarHBondContact O-N 3.33Å; I343-R346 PolarHBondContact O-N 2.87Å; I343-L347 HydrophobicContact CG2-CD1 3.65Å; I343-L347 HydrophobicContact CG2-CG 4.32Å; I343-L347 WeakPolarHBondContact O-CB 3.36Å; I343-L347 WeakPolarHBondContact O-CG 3.1Å; I343-L347 PolarHBondContact O-N 3.38Å; I343-V358 HydrophobicContact CG2-CG1 4.27Å; I343-V358 HydrophobicContact CG2-CG2 3.78Å; I343-M397 HydrophobicContact CD1-CE 3.89Å
344	S	93.4	Very high	93.1	Very high	1 Å²	1	72 Å²	72	1%	0.007	35%	0.345	C	S	.	.	H	α-helix	trans	-59.5	-47.2	177.3	-131.9	0	0	0	0	112	G340 V341 E342 R346 L347 R348 D355	G340-S344 WeakPolarHBondContact O-CB 3.29Å; G340-S344 PolarHBondContact O-N 3.04Å; V341-S344 PolarHBondContact O-N 3.42Å; E342-S344 VanDerWaalsContact C-N 3.34Å; S344-R346 VanDerWaalsContact C-N 3.31Å; S344-R346 PolarHBondContact O-N 3.46Å; S344-L347 PolarHBondContact O-N 3.08Å; S344-R348 VanDerWaalsContact O-CB 3.26Å; S344-R348 WeakPolarHBondContact O-CB 3.34Å; S344-R348 WeakPolarHBondContact O-CG 3.34Å; S344-R348 PolarHBondContact O-N 2.85Å; S344-D355 WeakPolarHBondContact CB-OD1 3.48Å; S344-D355 WeakPolarHBondContact OG-CA 3.32Å; S344-D355 PolarHBondContact OG-OD1 2.87Å
345	R	93.1	Very high	93.3	Very high	129 Å²	129	69.7 Å²	69.7	49%	0.487	33%	0.33	S	S	.	.	H	α-helix	trans	-57.6	-41	178.2	-173.7	175.4	72	145.1	4.4	112.8	V341 E342 I343	V341-R345 VanDerWaalsContact O-CB 3.25Å; V341-R345 WeakPolarHBondContact O-CB 3.34Å; V341-R345 PolarHBondContact O-N 2.92Å; E342-R345 VanDerWaalsContact CD-NH2 3.29Å; E342-R345 PolarHBondContact O-N 2.82Å; E342-R345 IonicContact OE1-NH2 3.7Å; E342-R345 PolarHBondContact OE1-NH2 3.29Å; E342-R345 VanDerWaalsContact OE1-NH2 3.11Å; E342-R345 IonicContact OE2-CZ 3.65Å; E342-R345 IonicContact OE2-NE 3.92Å; E342-R345 PolarHBondContact OE2-NE 3.39Å; E342-R345 IonicContact OE2-NH2 2.83Å; E342-R345 PolarHBondContact OE2-NH2 3.24Å; I343-R345 PolarHBondContact O-N 3.33Å
346	R	94.4	Very high	93.4	Very high	150 Å²	150	65.7 Å²	65.7	57%	0.566	31%	0.309	S	S	*	.	H	α-helix	trans	-72.3	-47	178.3	-69.8	-178.8	-172.2	-172.8	5.5	111.9	E342 I343 S344 R348 R349	E342-R346 WeakPolarHBondContact O-CG 3.35Å; E342-R346 PolarHBondContact O-N 3.38Å; E342-R346 IonicContact OE1-CZ 3.22Å; E342-R346 IonicContact OE1-NE 3.46Å; E342-R346 PolarHBondContact OE1-NE 3.24Å; E342-R346 IonicContact OE1-NH2 3.51Å; E342-R346 PolarHBondContact OE1-NH2 3.43Å; I343-R346 PolarHBondContact O-N 2.87Å; S344-R346 VanDerWaalsContact C-N 3.31Å; S344-R346 PolarHBondContact O-N 3.46Å; R346-R348 VanDerWaalsContact C-N 3.33Å; R346-R348 PolarHBondContact O-N 3.44Å; R346-R349 WeakPolarHBondContact O-CB 3.32Å; R346-R349 PolarHBondContact O-N 3.21Å
347	L	94.4	Very high	93.5	Very high	82 Å²	82	68.7 Å²	68.7	43%	0.429	33%	0.325	S	S	.	.	H	α-helix	trans	-67.9	-32.7	-178.2	-71.2	176.2	0	0	0	112.4	I343 S344 R349 F350 N351 A354 V358	I343-L347 HydrophobicContact CG2-CD1 3.65Å; I343-L347 HydrophobicContact CG2-CG 4.32Å; I343-L347 WeakPolarHBondContact O-CB 3.36Å; I343-L347 WeakPolarHBondContact O-CG 3.1Å; I343-L347 PolarHBondContact O-N 3.38Å; S344-L347 PolarHBondContact O-N 3.08Å; L347-R349 PolarHBondContact O-N 3.36Å; L347-R349 VanDerWaalsContact O-N 3.09Å; L347-F350 PolarHBondContact O-N 2.88Å; L347-N351 PolarHBondContact O-N 3.5Å; L347-A354 HydrophobicContact CB-CB 3.57Å; L347-V358 HydrophobicContact CD1-CG2 3.81Å
348	R	91.9	Very high	93.8	Very high	80 Å²	80	66.5 Å²	66.5	30%	0.302	31%	0.312	S	S	.	.	T	Hydrogen-bonded Turn	trans	-55.5	-25.5	174.9	-84.6	-171.7	-77	-149	9.3	113.7	S344 R346 F350 A354 D355 D404	S344-R348 VanDerWaalsContact O-CB 3.26Å; S344-R348 WeakPolarHBondContact O-CB 3.34Å; S344-R348 WeakPolarHBondContact O-CG 3.34Å; S344-R348 PolarHBondContact O-N 2.85Å; R346-R348 VanDerWaalsContact C-N 3.33Å; R346-R348 PolarHBondContact O-N 3.44Å; R348-F350 VanDerWaalsContact C-N 3.26Å; R348-F350 PolarHBondContact O-N 3.3Å; R348-A354 HydrophobicContact CB-CB 4.37Å; R348-A354 HydrophobicContact CG-CB 3.82Å; R348-D355 WeakPolarHBondContact CD-OD1 3.35Å; R348-D355 WeakPolarHBondContact CD-OD2 3.43Å; R348-D355 WeakPolarHBondContact CG-OD1 3.31Å; R348-D355 IonicContact CZ-OD1 3.65Å; R348-D355 IonicContact CZ-OD2 2.66Å; R348-D355 IonicContact NE-OD1 2.86Å; R348-D355 PolarHBondContact NE-OD1 2.92Å; R348-D355 IonicContact NE-OD2 3.11Å; R348-D355 IonicContact NH1-OD1 2.75Å; R348-D355 PolarHBondContact NH1-OD1 2.87Å; R348-D355 IonicContact NH1-OD2 3.07Å; R348-D355 PolarHBondContact NH1-OD2 3.32Å; R348-D404 IonicContact CZ-OD2 3.36Å; R348-D404 IonicContact NH1-OD2 2.89Å; R348-D404 PolarHBondContact NH1-OD2 3.14Å; R348-D404 IonicContact NH2-OD2 3.08Å
349	R	91.9	Very high	94	Very high	190 Å²	190	64.5 Å²	64.5	72%	0.717	29%	0.291	S	S	*	.	T	Hydrogen-bonded Turn	trans	-68.2	-26	177.1	-63.4	-177.5	-179.7	177.4	-1.1	113.1	R346 L347	R346-R349 WeakPolarHBondContact O-CB 3.32Å; R346-R349 PolarHBondContact O-N 3.21Å; L347-R349 PolarHBondContact O-N 3.36Å; L347-R349 VanDerWaalsContact O-N 3.09Å
350	F	93.5	Very high	94.2	Very high	179 Å²	179	60.5 Å²	60.5	79%	0.785	27%	0.27	S	S	*	.	T	Hydrogen-bonded Turn	trans	-114	-28.9	-174.8	-57.1	-75.9	0	0	0	112.7	L347 R348	L347-F350 PolarHBondContact O-N 2.88Å; R348-F350 VanDerWaalsContact C-N 3.26Å; R348-F350 PolarHBondContact O-N 3.3Å
351	N	93	Very high	94.3	Very high	58 Å²	58	63.4 Å²	63.4	31%	0.31	30%	0.295	S	S	.	.			trans	-134.2	114.2	-177.7	-171.9	-13.7	0	0	0	110.2	L347 R353 A354	L347-N351 PolarHBondContact O-N 3.5Å; N351-R353 PolarHBondContact O-N 3.43Å; N351-R353 VanDerWaalsContact O-N 3.14Å; N351-R353 WeakPolarHBondContact OD1-CB 3.2Å; N351-R353 PolarHBondContact OD1-N 2.9Å; N351-A354 VanDerWaalsContact O-CB 3.23Å; N351-A354 WeakPolarHBondContact O-CB 3.44Å; N351-A354 PolarHBondContact O-N 3.46Å; N351-A354 VanDerWaalsContact O-N 3.09Å
352	P	89.3	Confident	94.6	Very high	65 Å²	65	60.7 Å²	60.7	42%	0.422	28%	0.278	S	S	.	.	T	Hydrogen-bonded Turn	trans	-64.8	-14.5	178.1	28.4	-36.7	0	0	0	113.7	A354 E486	P352-A354 VanDerWaalsContact C-N 3.34Å; P352-E486 HydrophobicContact CB-CG 4.49Å; P352-E486 HydrophobicContact CG-CG 4.26Å; P352-E486 VanDerWaalsContact CG-OE1 3.24Å; P352-E486 WeakPolarHBondContact CG-OE1 3.23Å
353	R	93.7	Very high	94.8	Very high	92 Å²	92	58.3 Å²	58.3	35%	0.347	27%	0.267	S	S	.	.	T	Hydrogen-bonded Turn	trans	-90.2	7.9	175.3	-51	174.7	-174.9	-161.2	-5.8	113.5	N351 D355 P356 L357 A482 I485 E486	N351-R353 PolarHBondContact O-N 3.43Å; N351-R353 VanDerWaalsContact O-N 3.14Å; N351-R353 WeakPolarHBondContact OD1-CB 3.2Å; N351-R353 PolarHBondContact OD1-N 2.9Å; R353-D355 PolarHBondContact O-N 3.13Å; R353-P356 VanDerWaalsContact O-CD 3.27Å; R353-P356 WeakPolarHBondContact O-CD 3.41Å; R353-P356 WeakPolarHBondContact O-CG 3.38Å; R353-L357 HydrophobicContact CB-CD1 4.08Å; R353-L357 HydrophobicContact CB-CG 4.45Å; R353-L357 VanDerWaalsContact O-CG 3.31Å; R353-L357 WeakPolarHBondContact O-CG 3.19Å; R353-L357 PolarHBondContact O-N 3.33Å; R353-A482 HydrophobicContact CB-CB 4.49Å; R353-A482 VanDerWaalsContact CD-O 3.29Å; R353-A482 WeakPolarHBondContact CD-O 3.3Å; R353-I485 HydrophobicContact CB-CG2 4.1Å; R353-I485 HydrophobicContact CG-CG2 3.87Å; R353-E486 HydrophobicContact CG-CG 4.07Å; R353-E486 WeakPolarHBondContact CG-OE1 3.26Å; R353-E486 IonicContact CZ-OE1 2.7Å; R353-E486 IonicContact CZ-OE2 3.93Å; R353-E486 IonicContact NE-OE1 3.66Å; R353-E486 PolarHBondContact NE-OE1 2.91Å; R353-E486 IonicContact NE-OE2 3.9Å; R353-E486 IonicContact NH2-OE1 2.91Å; R353-E486 PolarHBondContact NH2-OE1 3.32Å; R353-E486 IonicContact NH2-OE2 2.72Å; R353-E486 PolarHBondContact NH2-OE2 2.94Å
354	A	94.4	Very high	94.8	Very high	1 Å²	1	58.3 Å²	58.3	1%	0.008	27%	0.267	C	S	.	.	H	α-helix	trans	-55.4	-46.1	-172.1	0	0	0	0	0	113.7	L347 R348 N351 P352 L357 V358	L347-A354 HydrophobicContact CB-CB 3.57Å; R348-A354 HydrophobicContact CB-CB 4.37Å; R348-A354 HydrophobicContact CG-CB 3.82Å; N351-A354 VanDerWaalsContact O-CB 3.23Å; N351-A354 WeakPolarHBondContact O-CB 3.44Å; N351-A354 PolarHBondContact O-N 3.46Å; N351-A354 VanDerWaalsContact O-N 3.09Å; P352-A354 VanDerWaalsContact C-N 3.34Å; A354-L357 PolarHBondContact O-N 3.48Å; A354-L357 VanDerWaalsContact O-N 3.16Å; A354-V358 WeakPolarHBondContact O-CG2 3.5Å; A354-V358 PolarHBondContact O-N 3.43Å
355	D	94	Very high	95	Very high	2 Å²	2	59.2 Å²	59.2	1%	0.011	28%	0.277	C	S	.	.	H	α-helix	trans	-54.7	-58.7	-175.5	-67	-8.2	0	0	0	113.1	S344 R348 R353 L357 V358 C359 I401 I405 Y408	S344-D355 WeakPolarHBondContact CB-OD1 3.48Å; S344-D355 WeakPolarHBondContact OG-CA 3.32Å; S344-D355 PolarHBondContact OG-OD1 2.87Å; R348-D355 WeakPolarHBondContact CD-OD1 3.35Å; R348-D355 WeakPolarHBondContact CD-OD2 3.43Å; R348-D355 WeakPolarHBondContact CG-OD1 3.31Å; R348-D355 IonicContact CZ-OD1 3.65Å; R348-D355 IonicContact CZ-OD2 2.66Å; R348-D355 IonicContact NE-OD1 2.86Å; R348-D355 PolarHBondContact NE-OD1 2.92Å; R348-D355 IonicContact NE-OD2 3.11Å; R348-D355 IonicContact NH1-OD1 2.75Å; R348-D355 PolarHBondContact NH1-OD1 2.87Å; R348-D355 IonicContact NH1-OD2 3.07Å; R348-D355 PolarHBondContact NH1-OD2 3.32Å; R353-D355 PolarHBondContact O-N 3.13Å; D355-L357 VanDerWaalsContact C-N 3.29Å; D355-L357 PolarHBondContact O-N 3.26Å; D355-V358 PolarHBondContact O-N 2.86Å; D355-C359 PolarHBondContact O-N 3.35Å; D355-C359 VanDerWaalsContact O-N 3.13Å; D355-I401 HydrophobicContact CB-CG2 3.55Å; D355-I401 WeakPolarHBondContact O-CG2 3.42Å; D355-I405 HydrophobicContact CB-CD1 4.27Å; D355-I405 HydrophobicContact CB-CG1 3.92Å; D355-Y408 WeakPolarHBondContact CB-OH 3.21Å; D355-Y408 WeakPolarHBondContact OD2-CE1 3.5Å; D355-Y408 PolarHBondContact OD2-OH 2.52Å
356	P	96.6	Very high	95.2	Very high	0 Å²	0	53.1 Å²	53.1	0%	0	25%	0.254	C	S	.	.	H	α-helix	trans	-65.5	-28.6	177.3	24.6	-34.3	0	0	0	113.7	R353 C359 A360 I405 T481 A482 I485	R353-P356 VanDerWaalsContact O-CD 3.27Å; R353-P356 WeakPolarHBondContact O-CD 3.41Å; R353-P356 WeakPolarHBondContact O-CG 3.38Å; P356-C359 PolarHBondContact O-N 3.29Å; P356-A360 WeakPolarHBondContact O-CB 3.2Å; P356-A360 PolarHBondContact O-N 2.96Å; P356-I405 HydrophobicContact CB-CD1 4.26Å; P356-T481 HydrophobicContact CB-CG2 3.83Å; P356-T481 HydrophobicContact CG-CG2 4.43Å; P356-A482 HydrophobicContact CB-CB 4.01Å; P356-A482 HydrophobicContact CG-CB 3.81Å; P356-I485 HydrophobicContact CG-CB 4.21Å; P356-I485 HydrophobicContact CG-CD1 4.47Å; P356-I485 HydrophobicContact CG-CG1 4.18Å; P356-I485 HydrophobicContact CG-CG2 4.08Å
357	L	97.3	Very high	95.3	Very high	62 Å²	62	46.4 Å²	46.4	33%	0.325	23%	0.231	S	C	.	.	H	α-helix	trans	-69.2	-37.2	175.6	-70	174.1	0	0	0	112.4	R353 A354 D355 A360 A361 L479 A482	R353-L357 HydrophobicContact CB-CD1 4.08Å; R353-L357 HydrophobicContact CB-CG 4.45Å; R353-L357 VanDerWaalsContact O-CG 3.31Å; R353-L357 WeakPolarHBondContact O-CG 3.19Å; R353-L357 PolarHBondContact O-N 3.33Å; A354-L357 PolarHBondContact O-N 3.48Å; A354-L357 VanDerWaalsContact O-N 3.16Å; D355-L357 VanDerWaalsContact C-N 3.29Å; D355-L357 PolarHBondContact O-N 3.26Å; L357-A360 PolarHBondContact O-N 2.97Å; L357-A361 WeakPolarHBondContact O-CB 3.24Å; L357-A361 PolarHBondContact O-N 3.16Å; L357-L479 HydrophobicContact CD2-CD2 4.09Å; L357-A482 HydrophobicContact CD2-CB 3.76Å; L357-A482 HydrophobicContact CG-CB 3.95Å
358	V	97.1	Very high	95.4	Very high	6 Å²	6	45.7 Å²	45.7	4%	0.036	23%	0.231	C	C	.	.	H	α-helix	trans	-67.1	-42.7	174.8	175.4	0	0	0	0	110.2	I343 L347 A354 D355 A360 A361 G362 M397 I401	I343-V358 HydrophobicContact CG2-CG1 4.27Å; I343-V358 HydrophobicContact CG2-CG2 3.78Å; L347-V358 HydrophobicContact CD1-CG2 3.81Å; A354-V358 WeakPolarHBondContact O-CG2 3.5Å; A354-V358 PolarHBondContact O-N 3.43Å; D355-V358 PolarHBondContact O-N 2.86Å; V358-A360 PolarHBondContact O-N 3.34Å; V358-A361 PolarHBondContact O-N 3.47Å; V358-G362 PolarHBondContact O-N 2.89Å; V358-M397 HydrophobicContact CG1-CE 3.71Å; V358-I401 HydrophobicContact CB-CD1 3.98Å; V358-I401 HydrophobicContact CG1-CD1 3.44Å; V358-I401 VanDerWaalsContact CG1-CD1 3.44Å
359	C	96.9	Very high	95.6	Very high	0 Å²	0	44.8 Å²	44.8	0%	0	23%	0.229	C	C	.	.	H	α-helix	trans	-60	-45.9	173.3	-67.2	0	0	0	0	112	D355 P356 A361 G362 L363 N398 I401 F478	D355-C359 PolarHBondContact O-N 3.35Å; D355-C359 VanDerWaalsContact O-N 3.13Å; P356-C359 PolarHBondContact O-N 3.29Å; C359-A361 PolarHBondContact O-N 3.09Å; C359-G362 PolarHBondContact O-N 3.02Å; C359-L363 WeakPolarHBondContact O-CB 3.45Å; C359-L363 PolarHBondContact O-N 3.18Å; C359-N398 VanDerWaalsContact C-OD1 3.32Å; C359-N398 WeakPolarHBondContact CA-OD1 3.25Å; C359-N398 WeakPolarHBondContact CB-OD1 3.44Å; C359-N398 PolarHBondContact O-OD1 3.42Å; C359-I401 VanDerWaalsContact SG-CG2 3.52Å; C359-F478 HydrophobicContact CB-CB 4.15Å; C359-F478 HydrophobicContact CB-CD1 3.72Å; C359-F478 HydrophobicContact CB-CD2 3.67Å; C359-F478 HydrophobicContact CB-CE1 3.96Å; C359-F478 HydrophobicContact CB-CE2 3.88Å; C359-F478 HydrophobicContact CB-CG 3.59Å; C359-F478 HydrophobicContact CB-CZ 4.03Å
360	A	97.8	Very high	95.8	Very high	1 Å²	1	36 Å²	36	1%	0.008	20%	0.196	C	C	.	.	H	α-helix	trans	-59.1	-46.8	176.2	0	0	0	0	0	112.1	P356 L357 V358 L363 L364 F478 L479	P356-A360 WeakPolarHBondContact O-CB 3.2Å; P356-A360 PolarHBondContact O-N 2.96Å; L357-A360 PolarHBondContact O-N 2.97Å; V358-A360 PolarHBondContact O-N 3.34Å; A360-L363 PolarHBondContact O-N 3.34Å; A360-L364 WeakPolarHBondContact O-CB 3.43Å; A360-L364 VanDerWaalsContact O-CG 3.28Å; A360-L364 WeakPolarHBondContact O-CG 3.29Å; A360-L364 PolarHBondContact O-N 3.09Å; A360-F478 HydrophobicContact CB-CB 3.73Å; A360-L479 HydrophobicContact CB-CD2 3.55Å; A360-L479 HydrophobicContact CB-CG 3.71Å
361	A	97.3	Very high	95.9	Very high	62 Å²	62	32 Å²	32	51%	0.512	18%	0.179	S	C	.	.	H	α-helix	trans	-63.2	-41.6	178.4	0	0	0	0	0	112.1	L357 V358 C359 G365	L357-A361 WeakPolarHBondContact O-CB 3.24Å; L357-A361 PolarHBondContact O-N 3.16Å; V358-A361 PolarHBondContact O-N 3.47Å; C359-A361 PolarHBondContact O-N 3.09Å; A361-G365 WeakPolarHBondContact O-CA 3.18Å; A361-G365 PolarHBondContact O-N 2.88Å
362	G	97.1	Very high	96.1	Very high	0 Å²	0	32.2 Å²	32.2	0%	0	18%	0.18	C	C	.	.	H	α-helix	trans	-61.9	-53.5	175.6	0	0	0	0	0	111.6	V358 C359 G365 S366 L394	V358-G362 PolarHBondContact O-N 2.89Å; C359-G362 PolarHBondContact O-N 3.02Å; G362-G365 PolarHBondContact O-N 2.98Å; G362-S366 WeakPolarHBondContact O-CB 3.5Å; G362-S366 PolarHBondContact O-N 3Å; G362-L394 CarbonylContact C-O 3.58Å; G362-L394 WeakPolarHBondContact CA-O 3.4Å; G362-L394 WeakPolarHBondContact O-CB 3.36Å
363	L	97	Very high	96.4	Very high	0 Å²	0	29.3 Å²	29.3	0%	0	16%	0.161	C	C	.	.	H	α-helix	trans	-72.6	-44.1	-175.1	-172.4	57.2	0	0	0	113.1	A282 V283 C359 A360 G365 S366 A367 L395 G471 G475 F478	A282-L363 HydrophobicContact CB-CD2 4.26Å; V283-L363 HydrophobicContact CG2-CD1 4.13Å; V283-L363 HydrophobicContact CG2-CD2 3.85Å; V283-L363 HydrophobicContact CG2-CG 4.49Å; C359-L363 WeakPolarHBondContact O-CB 3.45Å; C359-L363 PolarHBondContact O-N 3.18Å; A360-L363 PolarHBondContact O-N 3.34Å; L363-G365 VanDerWaalsContact C-N 3.31Å; L363-G365 PolarHBondContact O-N 3.16Å; L363-S366 PolarHBondContact O-N 3.37Å; L363-S366 PolarHBondContact O-OG 3.29Å; L363-A367 PolarHBondContact O-N 2.7Å; L363-L395 HydrophobicContact CD1-CD1 3.51Å; L363-G471 VanDerWaalsContact CG-O 3.29Å; L363-G471 WeakPolarHBondContact CG-O 3.47Å; L363-G475 VanDerWaalsContact CD2-N 3.34Å; L363-F478 HydrophobicContact CB-CD2 4.38Å; L363-F478 HydrophobicContact CD2-CD2 4.04Å; L363-F478 HydrophobicContact CD2-CE2 3.87Å
364	L	97.2	Very high	96.5	Very high	64 Å²	64	25.4 Å²	25.4	34%	0.335	15%	0.147	S	C	.	.	H	α-helix	trans	-63.4	-38.6	173.3	-69.5	176.5	0	0	0	111.7	A360 S366 A367 P368 A472 L479	A360-L364 WeakPolarHBondContact O-CB 3.43Å; A360-L364 VanDerWaalsContact O-CG 3.28Å; A360-L364 WeakPolarHBondContact O-CG 3.29Å; A360-L364 PolarHBondContact O-N 3.09Å; L364-S366 VanDerWaalsContact C-N 3.34Å; L364-A367 PolarHBondContact O-N 3.11Å; L364-P368 WeakPolarHBondContact O-CD 3.29Å; L364-A472 VanDerWaalsContact CD2-O 3.32Å; L364-A472 WeakPolarHBondContact CD2-O 3.39Å; L364-L479 HydrophobicContact CD1-CD1 3.69Å; L364-L479 HydrophobicContact CD1-CG 4.18Å
365	G	96.8	Very high	96.5	Very high	21 Å²	21	27.9 Å²	27.9	22%	0.216	17%	0.167	C	C	.	.	H	α-helix	trans	-66.7	-35.2	176.4	0	0	0	0	0	112.3	A361 G362 L363 A367 P368 F369	A361-G365 WeakPolarHBondContact O-CA 3.18Å; A361-G365 PolarHBondContact O-N 2.88Å; G362-G365 PolarHBondContact O-N 2.98Å; L363-G365 VanDerWaalsContact C-N 3.31Å; L363-G365 PolarHBondContact O-N 3.16Å; G365-A367 PolarHBondContact O-N 3.27Å; G365-P368 WeakPolarHBondContact O-CD 3.22Å; G365-P368 VanDerWaalsContact O-CG 3.27Å; G365-P368 WeakPolarHBondContact O-CG 3.43Å; G365-F369 WeakPolarHBondContact O-CD2 3.49Å
366	S	97.3	Very high	96.5	Very high	0 Å²	0	29.7 Å²	29.7	0%	0	18%	0.18	C	C	.	.	H	α-helix	trans	-65.5	-36.7	177.9	75.4	0	0	0	0	112.7	G362 L363 L364 F369 L370 G391	G362-S366 WeakPolarHBondContact O-CB 3.5Å; G362-S366 PolarHBondContact O-N 3Å; L363-S366 PolarHBondContact O-N 3.37Å; L363-S366 PolarHBondContact O-OG 3.29Å; L364-S366 VanDerWaalsContact C-N 3.34Å; S366-F369 PolarHBondContact O-N 3.3Å; S366-L370 WeakPolarHBondContact O-CG 3.17Å; S366-L370 PolarHBondContact O-N 3.03Å; S366-G391 WeakPolarHBondContact CB-O 3.21Å
367	A	96.1	Very high	96.3	Very high	10 Å²	10	29.7 Å²	29.7	8%	0.083	18%	0.18	C	C	.	.	H	α-helix	trans	-55.4	-50.9	-175.9	0	0	0	0	0	114.9	L363 L364 G365 F369 L370 F371 A468 A472	L363-A367 PolarHBondContact O-N 2.7Å; L364-A367 PolarHBondContact O-N 3.11Å; G365-A367 PolarHBondContact O-N 3.27Å; A367-F369 PolarHBondContact O-N 3.02Å; A367-L370 PolarHBondContact O-N 3.13Å; A367-F371 WeakPolarHBondContact O-CB 3.16Å; A367-F371 PolarHBondContact O-N 3.39Å; A367-A468 WeakPolarHBondContact CB-O 3.44Å; A367-A472 HydrophobicContact CB-CB 4.47Å
368	P	97	Very high	96.1	Very high	67 Å²	67	32.6 Å²	32.6	44%	0.435	19%	0.187	S	C	.	.	H	α-helix	trans	-65	-36.2	176.6	25.2	-34.7	0	0	0	112.5	L364 G365 F371 L372	L364-P368 WeakPolarHBondContact O-CD 3.29Å; G365-P368 WeakPolarHBondContact O-CD 3.22Å; G365-P368 VanDerWaalsContact O-CG 3.27Å; G365-P368 WeakPolarHBondContact O-CG 3.43Å; P368-F371 PolarHBondContact O-N 3.36Å; P368-L372 WeakPolarHBondContact O-CB 3.5Å; P368-L372 WeakPolarHBondContact O-CG 3.29Å; P368-L372 PolarHBondContact O-N 3.37Å
369	F	97.2	Very high	95.8	Very high	60 Å²	60	35.5 Å²	35.5	26%	0.263	22%	0.218	S	C	.	.	H	α-helix	trans	-69.4	-38.6	176.7	-71.2	-64.8	0	0	0	112.1	G365 S366 A367 L372 S373 F387 I390 L394	G365-F369 WeakPolarHBondContact O-CD2 3.49Å; S366-F369 PolarHBondContact O-N 3.3Å; A367-F369 PolarHBondContact O-N 3.02Å; F369-L372 HydrophobicContact CD1-CD1 4.42Å; F369-L372 PolarHBondContact O-N 3.02Å; F369-S373 WeakPolarHBondContact O-CB 3.47Å; F369-S373 PolarHBondContact O-N 3.14Å; F369-F387 AromaticContact CD1-CD1 3.67Å; F369-F387 HydrophobicContact CD1-CD1 3.67Å; F369-F387 HydrophobicContact CD1-CE1 4.16Å; F369-F387 HydrophobicContact CE1-CD1 4.22Å; F369-F387 HydrophobicContact CE1-CE1 4.34Å; F369-I390 HydrophobicContact CD1-CB 4.38Å; F369-I390 HydrophobicContact CD1-CG2 4.05Å; F369-I390 HydrophobicContact CD2-CB 4.49Å; F369-I390 HydrophobicContact CD2-CG2 3.53Å; F369-I390 HydrophobicContact CE1-CD1 4.24Å; F369-I390 HydrophobicContact CE1-CG2 4.08Å; F369-I390 HydrophobicContact CE2-CG2 3.59Å; F369-I390 HydrophobicContact CG-CB 4.29Å; F369-I390 HydrophobicContact CG-CG2 3.79Å; F369-I390 HydrophobicContact CZ-CG2 3.86Å; F369-L394 HydrophobicContact CD2-CD1 3.71Å; F369-L394 HydrophobicContact CE2-CD1 3.93Å
370	L	95.1	Very high	95.6	Very high	5 Å²	5	38 Å²	38	3%	0.026	24%	0.235	C	C	.	.	H	α-helix	trans	-62.2	-45.5	171.5	-68.5	177.1	0	0	0	110.9	V286 L290 S366 A367 L372 S373 L374	V286-L370 HydrophobicContact CG1-CD1 3.49Å; V286-L370 VanDerWaalsContact CG1-CD1 3.49Å; L290-L370 HydrophobicContact CD1-CD1 4.21Å; L290-L370 HydrophobicContact CD1-CD2 3.59Å; L290-L370 HydrophobicContact CD2-CD2 4.44Å; S366-L370 WeakPolarHBondContact O-CG 3.17Å; S366-L370 PolarHBondContact O-N 3.03Å; A367-L370 PolarHBondContact O-N 3.13Å; L370-L372 PolarHBondContact O-N 3.46Å; L370-S373 PolarHBondContact O-N 3.05Å; L370-S373 PolarHBondContact O-OG 2.93Å; L370-L374 WeakPolarHBondContact O-CG 3.15Å; L370-L374 PolarHBondContact O-N 2.83Å; L370-L374 VanDerWaalsContact O-N 3.16Å
371	F	95.9	Very high	95.4	Very high	95 Å²	95	38.3 Å²	38.3	42%	0.417	24%	0.237	S	C	.	.	H	α-helix	trans	-59	-47	174.4	175.5	-93	0	0	0	112.4	A367 P368 S373 L374 A375 M465 A468	A367-F371 WeakPolarHBondContact O-CB 3.16Å; A367-F371 PolarHBondContact O-N 3.39Å; P368-F371 PolarHBondContact O-N 3.36Å; F371-S373 VanDerWaalsContact C-N 3.32Å; F371-S373 PolarHBondContact O-N 2.64Å; F371-L374 PolarHBondContact O-N 3.18Å; F371-A375 HydrophobicContact CE1-CB 4.39Å; F371-A375 WeakPolarHBondContact O-CB 3.4Å; F371-A375 PolarHBondContact O-N 3.47Å; F371-M465 HydrophobicContact CD2-CE 4.14Å; F371-M465 HydrophobicContact CE2-CE 3.66Å; F371-A468 HydrophobicContact CB-CB 4.3Å
372	L	96.3	Very high	95.3	Very high	64 Å²	64	39.8 Å²	39.8	34%	0.335	24%	0.239	S	C	.	.	H	α-helix	trans	-62.6	-38.6	177.5	-73.3	171.2	0	0	0	111.8	P368 F369 L370 L374 A375 C376 F387	P368-L372 WeakPolarHBondContact O-CB 3.5Å; P368-L372 WeakPolarHBondContact O-CG 3.29Å; P368-L372 PolarHBondContact O-N 3.37Å; F369-L372 HydrophobicContact CD1-CD1 4.42Å; F369-L372 PolarHBondContact O-N 3.02Å; L370-L372 PolarHBondContact O-N 3.46Å; L372-L374 VanDerWaalsContact C-N 3.29Å; L372-L374 PolarHBondContact O-N 3.33Å; L372-A375 PolarHBondContact O-N 2.87Å; L372-C376 VanDerWaalsContact O-CB 3.28Å; L372-C376 WeakPolarHBondContact O-CB 3.31Å; L372-C376 PolarHBondContact O-N 3.32Å; L372-C376 PolarHBondContact O-SG 3.42Å; L372-C376 VanDerWaalsContact O-SG 3.4Å; L372-F387 HydrophobicContact CB-CD1 4.4Å; L372-F387 HydrophobicContact CB-CD2 3.82Å; L372-F387 HydrophobicContact CB-CE1 4.48Å; L372-F387 HydrophobicContact CB-CE2 3.92Å; L372-F387 HydrophobicContact CB-CG 4.07Å; L372-F387 HydrophobicContact CB-CZ 4.25Å; L372-F387 HydrophobicContact CD1-CE1 4.19Å; L372-F387 HydrophobicContact CD1-CZ 4.25Å
373	S	96.3	Very high	95.2	Very high	4 Å²	4	41 Å²	41	3%	0.028	25%	0.249	C	C	.	.	H	α-helix	trans	-58.9	-42.1	175.8	80	0	0	0	0	111.8	F369 L370 F371 A377 T384	F369-S373 WeakPolarHBondContact O-CB 3.47Å; F369-S373 PolarHBondContact O-N 3.14Å; L370-S373 PolarHBondContact O-N 3.05Å; L370-S373 PolarHBondContact O-OG 2.93Å; F371-S373 VanDerWaalsContact C-N 3.32Å; F371-S373 PolarHBondContact O-N 2.64Å; S373-A377 PolarHBondContact O-N 3.39Å; S373-T384 VanDerWaalsContact O-CG2 3.31Å; S373-T384 WeakPolarHBondContact O-CG2 3.32Å; S373-T384 PolarHBondContact O-OG1 3.35Å
374	L	95.4	Very high	95.1	Very high	9 Å²	9	41 Å²	41	5%	0.047	25%	0.249	C	C	.	.	H	α-helix	trans	-70.6	-44.5	177.2	-61.9	174.8	0	0	0	111.1	F297 L370 F371 L372 C376 A377 Q461 L464 M465	F297-L374 HydrophobicContact CD1-CD2 4.27Å; F297-L374 HydrophobicContact CE1-CD2 3.73Å; F297-L374 HydrophobicContact CE2-CD2 4.12Å; F297-L374 HydrophobicContact CZ-CD2 3.64Å; L370-L374 WeakPolarHBondContact O-CG 3.15Å; L370-L374 PolarHBondContact O-N 2.83Å; L370-L374 VanDerWaalsContact O-N 3.16Å; F371-L374 PolarHBondContact O-N 3.18Å; L372-L374 VanDerWaalsContact C-N 3.29Å; L372-L374 PolarHBondContact O-N 3.33Å; L374-C376 PolarHBondContact O-N 3.13Å; L374-A377 WeakPolarHBondContact O-CB 3.15Å; L374-A377 PolarHBondContact O-N 3.26Å; L374-Q461 HydrophobicContact CB-CG 4.36Å; L374-Q461 PolarHBondContact O-NE2 2.73Å; L374-L464 HydrophobicContact CD1-CB 3.78Å; L374-L464 HydrophobicContact CD2-CB 3.82Å; L374-L464 HydrophobicContact CD2-CD1 3.96Å; L374-L464 HydrophobicContact CG-CB 4.48Å; L374-M465 HydrophobicContact CD1-CG 3.99Å
375	A	94.4	Very high	95.1	Very high	53 Å²	53	39.1 Å²	39.1	44%	0.438	24%	0.238	S	C	.	.	H	α-helix	trans	-65.1	-39.1	-178.5	0	0	0	0	0	112.5	F371 L372	F371-A375 HydrophobicContact CE1-CB 4.39Å; F371-A375 WeakPolarHBondContact O-CB 3.4Å; F371-A375 PolarHBondContact O-N 3.47Å; L372-A375 PolarHBondContact O-N 2.87Å
376	C	94.4	Very high	95.1	Very high	40 Å²	40	42.5 Å²	42.5	27%	0.27	25%	0.25	S	C	.	.	H	α-helix	trans	-81.9	-10.6	-178.5	-68.1	0	0	0	0	114.2	L372 L374 R378 G379 S380 A383 F387	L372-C376 VanDerWaalsContact O-CB 3.28Å; L372-C376 WeakPolarHBondContact O-CB 3.31Å; L372-C376 PolarHBondContact O-N 3.32Å; L372-C376 PolarHBondContact O-SG 3.42Å; L372-C376 VanDerWaalsContact O-SG 3.4Å; L374-C376 PolarHBondContact O-N 3.13Å; C376-R378 VanDerWaalsContact C-N 3.25Å; C376-R378 PolarHBondContact O-N 2.98Å; C376-R378 VanDerWaalsContact O-N 3.15Å; C376-G379 WeakPolarHBondContact O-CA 3.25Å; C376-G379 PolarHBondContact O-N 3.1Å; C376-S380 PolarHBondContact O-N 2.95Å; C376-A383 HydrophobicContact CB-CB 4.32Å; C376-F387 HydrophobicContact CB-CD2 4.47Å; C376-F387 HydrophobicContact CB-CE2 4.35Å
377	A	93.5	Very high	95.2	Very high	0 Å²	0	44.6 Å²	44.6	0%	0	26%	0.259	C	S	.	.	T	Hydrogen-bonded Turn	trans	-55.6	-37.4	-173.9	0	0	0	0	0	113.7	F297 S301 S373 L374 T384 F457	F297-A377 HydrophobicContact CE1-CB 3.61Å; F297-A377 HydrophobicContact CZ-CB 3.48Å; F297-A377 VanDerWaalsContact CZ-CB 3.48Å; S301-A377 PolarHBondContact OG-O 2.89Å; S373-A377 PolarHBondContact O-N 3.39Å; L374-A377 WeakPolarHBondContact O-CB 3.15Å; L374-A377 PolarHBondContact O-N 3.26Å; A377-T384 WeakPolarHBondContact CA-OG1 3.16Å; A377-T384 HydrophobicContact CB-CG2 4.44Å; A377-T384 PolarHBondContact N-OG1 3.25Å; A377-T384 VanDerWaalsContact N-OG1 3.16Å; A377-F457 HydrophobicContact CB-CE2 4.09Å; A377-F457 HydrophobicContact CB-CZ 3.9Å
378	R	91.4	Very high	95.2	Very high	124 Å²	124	44.6 Å²	44.6	47%	0.468	26%	0.258	S	S	.	.	T	Hydrogen-bonded Turn	trans	-79.1	-16.5	176.3	-168.6	178.9	176.2	-165.8	2.6	113.9	L305 C376 F457	L305-R378 WeakPolarHBondContact CD2-O 3.45Å; C376-R378 VanDerWaalsContact C-N 3.25Å; C376-R378 PolarHBondContact O-N 2.98Å; C376-R378 VanDerWaalsContact O-N 3.15Å; R378-F457 HydrophobicContact CB-CE1 4.19Å; R378-F457 HydrophobicContact CB-CZ 4.37Å
379	G	90.8	Very high	95.2	Very high	67 Å²	67	44.9 Å²	44.9	69%	0.691	25%	0.252	S	S	*	.	T	Hydrogen-bonded Turn	trans	-97.2	-44.8	-178	0	0	0	0	0	113	C376	C376-G379 WeakPolarHBondContact O-CA 3.25Å; C376-G379 PolarHBondContact O-N 3.1Å
380	S	94	Very high	95.3	Very high	51 Å²	51	44.6 Å²	44.6	36%	0.357	25%	0.253	S	S	.	.			trans	-155	114.7	-178.1	176	0	0	0	0	110.8	C376 V382 A383 T384	C376-S380 PolarHBondContact O-N 2.95Å; S380-V382 VanDerWaalsContact C-N 3.26Å; S380-V382 PolarHBondContact O-N 3.12Å; S380-A383 PolarHBondContact O-N 3.12Å; S380-A383 PolarHBondContact OG-N 3.24Å; S380-T384 PolarHBondContact O-N 3.37Å; S380-T384 PolarHBondContact O-OG1 3.44Å
381	I	93.4	Very high	95.4	Very high	9 Å²	9	44.4 Å²	44.4	5%	0.046	25%	0.252	C	S	.	.	H	α-helix	trans	-63.9	-33.7	176.5	-162.6	67	0	0	0	111.9	L298 R302 T384 Y385	L298-I381 HydrophobicContact CB-CD1 4.46Å; L298-I381 HydrophobicContact CD2-CD1 3.57Å; L298-I381 HydrophobicContact CD2-CG1 4.5Å; R302-I381 HydrophobicContact CG-CD1 4.09Å; R302-I381 HydrophobicContact CG-CG1 4.13Å; I381-T384 WeakPolarHBondContact O-CB 3.25Å; I381-T384 PolarHBondContact O-N 2.88Å; I381-Y385 HydrophobicContact CG1-CD2 4.23Å; I381-Y385 HydrophobicContact CG1-CE2 3.76Å; I381-Y385 VanDerWaalsContact O-CD2 3.22Å; I381-Y385 WeakPolarHBondContact O-CD2 3.44Å; I381-Y385 PolarHBondContact O-N 3.48Å
382	V	93.8	Very high	95.4	Very high	93 Å²	93	41 Å²	41	56%	0.564	24%	0.237	S	C	*	.	H	α-helix	trans	-65.5	-44	177.8	179.6	0	0	0	0	110.9	S380 T384 Y385 I386	S380-V382 VanDerWaalsContact C-N 3.26Å; S380-V382 PolarHBondContact O-N 3.12Å; V382-T384 VanDerWaalsContact C-N 3.29Å; V382-T384 PolarHBondContact O-N 3.3Å; V382-Y385 PolarHBondContact O-N 3.06Å; V382-I386 HydrophobicContact CG1-CD1 4.24Å; V382-I386 WeakPolarHBondContact O-CG1 3.24Å; V382-I386 PolarHBondContact O-N 2.7Å; V382-I386 VanDerWaalsContact O-N 3.1Å
383	A	95.6	Very high	95.4	Very high	26 Å²	26	38.6 Å²	38.6	22%	0.215	23%	0.225	C	C	.	.	H	α-helix	trans	-61.4	-40.7	175.2	0	0	0	0	0	111.2	C376 S380 Y385 I386 F387	C376-A383 HydrophobicContact CB-CB 4.32Å; S380-A383 PolarHBondContact O-N 3.12Å; S380-A383 PolarHBondContact OG-N 3.24Å; A383-Y385 PolarHBondContact O-N 3.3Å; A383-I386 PolarHBondContact O-N 3.41Å; A383-F387 HydrophobicContact CB-CE2 4.31Å; A383-F387 WeakPolarHBondContact O-CD2 3.05Å; A383-F387 WeakPolarHBondContact O-CG 3.31Å; A383-F387 PolarHBondContact O-N 3.42Å
384	T	96.1	Very high	95.5	Very high	0 Å²	0	40.3 Å²	40.3	0%	0	23%	0.234	C	C	.	.	H	α-helix	trans	-59.5	-44.5	174.7	-66.5	0	0	0	0	112.1	L298 S373 A377 S380 I381 V382 I386 F387 I388	L298-T384 HydrophobicContact CD2-CG2 3.66Å; S373-T384 VanDerWaalsContact O-CG2 3.31Å; S373-T384 WeakPolarHBondContact O-CG2 3.32Å; S373-T384 PolarHBondContact O-OG1 3.35Å; A377-T384 WeakPolarHBondContact CA-OG1 3.16Å; A377-T384 HydrophobicContact CB-CG2 4.44Å; A377-T384 PolarHBondContact N-OG1 3.25Å; A377-T384 VanDerWaalsContact N-OG1 3.16Å; S380-T384 PolarHBondContact O-N 3.37Å; S380-T384 PolarHBondContact O-OG1 3.44Å; I381-T384 WeakPolarHBondContact O-CB 3.25Å; I381-T384 PolarHBondContact O-N 2.88Å; V382-T384 VanDerWaalsContact C-N 3.29Å; V382-T384 PolarHBondContact O-N 3.3Å; T384-I386 PolarHBondContact O-N 3.02Å; T384-F387 PolarHBondContact O-N 2.97Å; T384-I388 HydrophobicContact CG2-CD1 3.84Å; T384-I388 HydrophobicContact CG2-CG1 4.36Å; T384-I388 VanDerWaalsContact O-CG1 3.3Å; T384-I388 WeakPolarHBondContact O-CG1 3.27Å; T384-I388 PolarHBondContact O-N 3.46Å
385	Y	96.4	Very high	95.5	Very high	24 Å²	24	40 Å²	40	9%	0.094	23%	0.232	C	C	.	.	H	α-helix	trans	-60.2	-43.3	175.6	-78.8	-55.9	0	0	0	113.3	L298 D321 I324 I328 I381 V382 A383 F387 I388 F389	L298-Y385 HydrophobicContact CD1-CD1 4.35Å; L298-Y385 HydrophobicContact CD1-CE1 3.51Å; L298-Y385 HydrophobicContact CD2-CE1 4.11Å; L298-Y385 HydrophobicContact CG-CE1 4.43Å; D321-Y385 WeakPolarHBondContact CA-OH 3.25Å; D321-Y385 WeakPolarHBondContact CB-OH 3.37Å; D321-Y385 PolarHBondContact OD1-OH 3.09Å; I324-Y385 HydrophobicContact CB-CE1 4Å; I324-Y385 HydrophobicContact CD1-CE2 4.23Å; I324-Y385 HydrophobicContact CG2-CD1 3.7Å; I324-Y385 HydrophobicContact CG2-CD2 4.44Å; I324-Y385 HydrophobicContact CG2-CE1 3.41Å; I324-Y385 VanDerWaalsContact CG2-CE1 3.41Å; I324-Y385 HydrophobicContact CG2-CE2 4.23Å; I324-Y385 HydrophobicContact CG2-CG 4.21Å; I328-Y385 HydrophobicContact CD1-CD1 3.53Å; I328-Y385 HydrophobicContact CD1-CE1 4.27Å; I328-Y385 HydrophobicContact CD1-CG 4.29Å; I381-Y385 HydrophobicContact CG1-CD2 4.23Å; I381-Y385 HydrophobicContact CG1-CE2 3.76Å; I381-Y385 VanDerWaalsContact O-CD2 3.22Å; I381-Y385 WeakPolarHBondContact O-CD2 3.44Å; I381-Y385 PolarHBondContact O-N 3.48Å; V382-Y385 PolarHBondContact O-N 3.06Å; A383-Y385 PolarHBondContact O-N 3.3Å; Y385-F387 VanDerWaalsContact C-N 3.33Å; Y385-F387 PolarHBondContact O-N 3.17Å; Y385-I388 PolarHBondContact O-N 3.42Å; Y385-F389 WeakPolarHBondContact O-CB 3.47Å; Y385-F389 PolarHBondContact O-N 3.42Å
386	I	97.6	Very high	95.5	Very high	92 Å²	92	38 Å²	38	47%	0.472	22%	0.215	S	C	.	.	H	α-helix	trans	-62	-44.1	177.7	-66.9	167.3	0	0	0	110.4	V382 A383 T384 F389 I390	V382-I386 HydrophobicContact CG1-CD1 4.24Å; V382-I386 WeakPolarHBondContact O-CG1 3.24Å; V382-I386 PolarHBondContact O-N 2.7Å; V382-I386 VanDerWaalsContact O-N 3.1Å; A383-I386 PolarHBondContact O-N 3.41Å; T384-I386 PolarHBondContact O-N 3.02Å; I386-F389 WeakPolarHBondContact O-CB 3.29Å; I386-F389 PolarHBondContact O-N 3.46Å; I386-I390 HydrophobicContact CG2-CD1 4Å; I386-I390 WeakPolarHBondContact O-CG1 3.49Å; I386-I390 PolarHBondContact O-N 3.4Å
387	F	97.7	Very high	95.5	Very high	44 Å²	44	36.9 Å²	36.9	19%	0.193	21%	0.206	C	C	.	.	H	α-helix	trans	-70	-35.7	178.8	-67	-42	0	0	0	113.3	F369 L372 C376 A383 T384 Y385 G391	F369-F387 AromaticContact CD1-CD1 3.67Å; F369-F387 HydrophobicContact CD1-CD1 3.67Å; F369-F387 HydrophobicContact CD1-CE1 4.16Å; F369-F387 HydrophobicContact CE1-CD1 4.22Å; F369-F387 HydrophobicContact CE1-CE1 4.34Å; L372-F387 HydrophobicContact CB-CD1 4.4Å; L372-F387 HydrophobicContact CB-CD2 3.82Å; L372-F387 HydrophobicContact CB-CE1 4.48Å; L372-F387 HydrophobicContact CB-CE2 3.92Å; L372-F387 HydrophobicContact CB-CG 4.07Å; L372-F387 HydrophobicContact CB-CZ 4.25Å; L372-F387 HydrophobicContact CD1-CE1 4.19Å; L372-F387 HydrophobicContact CD1-CZ 4.25Å; C376-F387 HydrophobicContact CB-CD2 4.47Å; C376-F387 HydrophobicContact CB-CE2 4.35Å; A383-F387 HydrophobicContact CB-CE2 4.31Å; A383-F387 WeakPolarHBondContact O-CD2 3.05Å; A383-F387 WeakPolarHBondContact O-CG 3.31Å; A383-F387 PolarHBondContact O-N 3.42Å; T384-F387 PolarHBondContact O-N 2.97Å; Y385-F387 VanDerWaalsContact C-N 3.33Å; Y385-F387 PolarHBondContact O-N 3.17Å; F387-G391 PolarHBondContact O-N 3.29Å
388	I	96.9	Very high	95.5	Very high	10 Å²	10	36.9 Å²	36.9	5%	0.051	21%	0.206	C	C	.	.	H	α-helix	trans	-60.1	-47.9	170.1	-71.1	171	0	0	0	109.7	L298 F325 I328 T384 Y385 I390 G391 E392	L298-I388 HydrophobicContact CD1-CD1 4.19Å; L298-I388 HydrophobicContact CD2-CD1 4.09Å; L298-I388 HydrophobicContact CG-CD1 4.43Å; F325-I388 HydrophobicContact CD2-CG2 4.17Å; F325-I388 HydrophobicContact CE2-CG2 3.87Å; I328-I388 HydrophobicContact CG2-CG2 4.18Å; T384-I388 HydrophobicContact CG2-CD1 3.84Å; T384-I388 HydrophobicContact CG2-CG1 4.36Å; T384-I388 VanDerWaalsContact O-CG1 3.3Å; T384-I388 WeakPolarHBondContact O-CG1 3.27Å; T384-I388 PolarHBondContact O-N 3.46Å; Y385-I388 PolarHBondContact O-N 3.42Å; I388-I390 PolarHBondContact O-N 2.79Å; I388-G391 PolarHBondContact O-N 2.72Å; I388-E392 VanDerWaalsContact O-CB 3.27Å; I388-E392 WeakPolarHBondContact O-CB 3.4Å; I388-E392 PolarHBondContact O-N 3.35Å
389	F	97.8	Very high	95.3	Very high	72 Å²	72	36.3 Å²	36.3	32%	0.316	20%	0.204	S	C	.	.	H	α-helix	trans	-57.1	-47.8	179.8	177.8	-87	0	0	0	112.2	I328 L331 T332 L335 Y385 I386 T393	I328-F389 HydrophobicContact CG2-CB 4.09Å; I328-F389 HydrophobicContact CG2-CD2 4.08Å; L331-F389 HydrophobicContact CB-CE2 4.17Å; T332-F389 HydrophobicContact CG2-CB 4.4Å; T332-F389 HydrophobicContact CG2-CD2 3.46Å; T332-F389 VanDerWaalsContact CG2-CD2 3.46Å; T332-F389 HydrophobicContact CG2-CE2 3.76Å; T332-F389 HydrophobicContact CG2-CG 3.95Å; T332-F389 HydrophobicContact CG2-CZ 4.46Å; T332-F389 VanDerWaalsContact CG2-O 3.29Å; T332-F389 WeakPolarHBondContact CG2-O 3.43Å; L335-F389 HydrophobicContact CD1-CZ 3.98Å; Y385-F389 WeakPolarHBondContact O-CB 3.47Å; Y385-F389 PolarHBondContact O-N 3.42Å; I386-F389 WeakPolarHBondContact O-CB 3.29Å; I386-F389 PolarHBondContact O-N 3.46Å; F389-T393 WeakPolarHBondContact O-CB 3.26Å; F389-T393 PolarHBondContact O-N 2.58Å; F389-T393 PolarHBondContact O-OG1 2.97Å
390	I	98	Very high	95.1	Very high	55 Å²	55	34.7 Å²	34.7	28%	0.282	18%	0.184	S	C	.	.	H	α-helix	trans	-66.8	-47.4	178.7	-62.6	167.8	0	0	0	110.5	F369 I386 I388 E392 T393 L394	F369-I390 HydrophobicContact CD1-CB 4.38Å; F369-I390 HydrophobicContact CD1-CG2 4.05Å; F369-I390 HydrophobicContact CD2-CB 4.49Å; F369-I390 HydrophobicContact CD2-CG2 3.53Å; F369-I390 HydrophobicContact CE1-CD1 4.24Å; F369-I390 HydrophobicContact CE1-CG2 4.08Å; F369-I390 HydrophobicContact CE2-CG2 3.59Å; F369-I390 HydrophobicContact CG-CB 4.29Å; F369-I390 HydrophobicContact CG-CG2 3.79Å; F369-I390 HydrophobicContact CZ-CG2 3.86Å; I386-I390 HydrophobicContact CG2-CD1 4Å; I386-I390 WeakPolarHBondContact O-CG1 3.49Å; I386-I390 PolarHBondContact O-N 3.4Å; I388-I390 PolarHBondContact O-N 2.79Å; I390-E392 PolarHBondContact O-N 3.43Å; I390-T393 PolarHBondContact O-N 3.08Å; I390-L394 HydrophobicContact CG2-CD1 3.98Å; I390-L394 HydrophobicContact CG2-CG 4.45Å; I390-L394 VanDerWaalsContact O-CG 3.3Å; I390-L394 WeakPolarHBondContact O-CG 3.38Å; I390-L394 PolarHBondContact O-N 2.82Å
391	G	97.1	Very high	95	Very high	0 Å²	0	32.3 Å²	32.3	0%	0	17%	0.167	C	C	.	.	H	α-helix	trans	-59.9	-45.9	-179.3	0	0	0	0	0	112.8	S366 F387 I388 L394 L395	S366-G391 WeakPolarHBondContact CB-O 3.21Å; F387-G391 PolarHBondContact O-N 3.29Å; I388-G391 PolarHBondContact O-N 2.72Å; G391-L394 PolarHBondContact O-N 2.7Å; G391-L395 WeakPolarHBondContact O-CB 3.49Å; G391-L395 PolarHBondContact O-N 3.38Å
392	E	96.2	Very high	94.9	Very high	24 Å²	24	32 Å²	32	11%	0.112	17%	0.166	C	C	.	.	H	α-helix	trans	-71	-34.4	179.4	-166.2	-175.7	-159.1	0	0	112.3	I328 T329 T332 I388 I390 L395 S396	I328-E392 WeakPolarHBondContact CG2-OE2 3.48Å; T329-E392 WeakPolarHBondContact CA-OE1 3.31Å; T329-E392 WeakPolarHBondContact CA-OE2 3.37Å; T329-E392 WeakPolarHBondContact CB-OE1 3.31Å; T329-E392 WeakPolarHBondContact CG2-OE1 3.41Å; T329-E392 PolarHBondContact OG1-OE1 3.41Å; T332-E392 HydrophobicContact CG2-CB 4.2Å; T332-E392 WeakPolarHBondContact OG1-CG 3.39Å; T332-E392 PolarHBondContact OG1-OE2 2.89Å; I388-E392 VanDerWaalsContact O-CB 3.27Å; I388-E392 WeakPolarHBondContact O-CB 3.4Å; I388-E392 PolarHBondContact O-N 3.35Å; I390-E392 PolarHBondContact O-N 3.43Å; E392-L395 PolarHBondContact O-N 3.38Å; E392-S396 VanDerWaalsContact O-CB 3.25Å; E392-S396 WeakPolarHBondContact O-CB 3.4Å; E392-S396 PolarHBondContact O-N 2.89Å; E392-S396 PolarHBondContact O-OG 3.19Å
393	T	96.8	Very high	94.5	Very high	14 Å²	14	30 Å²	30	9%	0.086	16%	0.159	C	C	.	.	H	α-helix	trans	-61.3	-48.3	172.7	-60.5	0	0	0	0	110.5	T332 G336 L339 F389 I390 L395 S396 M397	T332-T393 WeakPolarHBondContact CG2-OG1 3.46Å; G336-T393 WeakPolarHBondContact CA-O 3.36Å; L339-T393 HydrophobicContact CD1-CG2 4.18Å; F389-T393 WeakPolarHBondContact O-CB 3.26Å; F389-T393 PolarHBondContact O-N 2.58Å; F389-T393 PolarHBondContact O-OG1 2.97Å; I390-T393 PolarHBondContact O-N 3.08Å; T393-L395 VanDerWaalsContact C-N 3.34Å; T393-L395 PolarHBondContact O-N 2.98Å; T393-S396 PolarHBondContact O-N 2.86Å; T393-M397 WeakPolarHBondContact O-CG 3.24Å; T393-M397 PolarHBondContact O-N 3.42Å
394	L	97.4	Very high	94	Very high	39 Å²	39	31.7 Å²	31.7	20%	0.204	16%	0.164	C	C	.	.	H	α-helix	trans	-64.7	-37.6	178.5	-69	174.4	0	0	0	112.1	G362 F369 I390 G391 M397 N398	G362-L394 CarbonylContact C-O 3.58Å; G362-L394 WeakPolarHBondContact CA-O 3.4Å; G362-L394 WeakPolarHBondContact O-CB 3.36Å; F369-L394 HydrophobicContact CD2-CD1 3.71Å; F369-L394 HydrophobicContact CE2-CD1 3.93Å; I390-L394 HydrophobicContact CG2-CD1 3.98Å; I390-L394 HydrophobicContact CG2-CG 4.45Å; I390-L394 VanDerWaalsContact O-CG 3.3Å; I390-L394 WeakPolarHBondContact O-CG 3.38Å; I390-L394 PolarHBondContact O-N 2.82Å; G391-L394 PolarHBondContact O-N 2.7Å; L394-M397 HydrophobicContact CD2-SD 3.82Å; L394-M397 PolarHBondContact O-N 2.86Å; L394-N398 PolarHBondContact O-ND2 3.16Å
395	L	95.4	Very high	93.8	Very high	2 Å²	2	31.7 Å²	31.7	1%	0.01	16%	0.164	C	C	.	.	H	α-helix	trans	-63.6	-42.3	173.7	-170.1	65.5	0	0	0	111.3	V283 V286 T287 L363 G391 E392 T393 M397 N398	V283-L395 HydrophobicContact CB-CD1 4.3Å; V283-L395 HydrophobicContact CG1-CD1 3.88Å; V283-L395 HydrophobicContact CG1-CG 4.13Å; V283-L395 HydrophobicContact CG2-CD1 4.35Å; V286-L395 HydrophobicContact CB-CD1 4.34Å; V286-L395 HydrophobicContact CB-CD2 4.23Å; V286-L395 HydrophobicContact CG1-CD1 4.28Å; V286-L395 HydrophobicContact CG1-CD2 3.73Å; T287-L395 VanDerWaalsContact OG1-CD2 3.31Å; T287-L395 WeakPolarHBondContact OG1-CD2 3.44Å; L363-L395 HydrophobicContact CD1-CD1 3.51Å; G391-L395 WeakPolarHBondContact O-CB 3.49Å; G391-L395 PolarHBondContact O-N 3.38Å; E392-L395 PolarHBondContact O-N 3.38Å; T393-L395 VanDerWaalsContact C-N 3.34Å; T393-L395 PolarHBondContact O-N 2.98Å; L395-M397 VanDerWaalsContact C-N 3.26Å; L395-M397 PolarHBondContact O-N 3.39Å; L395-N398 PolarHBondContact O-N 2.82Å; L395-N398 PolarHBondContact O-ND2 3.43Å
396	S	94.5	Very high	93.5	Very high	13 Å²	13	30.6 Å²	30.6	9%	0.091	16%	0.16	C	C	.	.	H	α-helix	trans	-69.5	-19.1	-177.4	-64.7	0	0	0	0	113.9	V337 E392 T393 N398	V337-S396 WeakPolarHBondContact CG2-O 3.29Å; E392-S396 VanDerWaalsContact O-CB 3.25Å; E392-S396 WeakPolarHBondContact O-CB 3.4Å; E392-S396 PolarHBondContact O-N 2.89Å; E392-S396 PolarHBondContact O-OG 3.19Å; T393-S396 PolarHBondContact O-N 2.86Å; S396-N398 PolarHBondContact O-N 2.97Å; S396-N398 VanDerWaalsContact O-N 3.16Å
397	M	94.2	Very high	92.8	Very high	15 Å²	15	29.2 Å²	29.2	7%	0.074	15%	0.153	C	C	.	.	T	Hydrogen-bonded Turn	trans	-59.7	-23.9	175	-70	171.8	59.8	0	0	114.1	G336 I343 V358 T393 L394 L395 I401	G336-M397 VanDerWaalsContact O-CA 3.29Å; G336-M397 WeakPolarHBondContact O-CA 3.3Å; G336-M397 VanDerWaalsContact O-CG 3.27Å; G336-M397 WeakPolarHBondContact O-CG 3.21Å; I343-M397 HydrophobicContact CD1-CE 3.89Å; V358-M397 HydrophobicContact CG1-CE 3.71Å; T393-M397 WeakPolarHBondContact O-CG 3.24Å; T393-M397 PolarHBondContact O-N 3.42Å; L394-M397 HydrophobicContact CD2-SD 3.82Å; L394-M397 PolarHBondContact O-N 2.86Å; L395-M397 VanDerWaalsContact C-N 3.26Å; L395-M397 PolarHBondContact O-N 3.39Å; M397-I401 WeakPolarHBondContact O-CD1 3.4Å
398	N	93.7	Very high	92.2	Very high	0 Å²	0	29 Å²	29	0%	0	15%	0.151	C	C	.	.	H	α-helix	trans	-77.1	-31.2	-170.5	-64.7	-83.7	0	0	0	113.8	V283 C359 L394 L395 S396 A400 I401 V402	V283-N398 HydrophobicContact CG1-CB 4.43Å; V283-N398 HydrophobicContact CG2-CB 3.89Å; C359-N398 VanDerWaalsContact C-OD1 3.32Å; C359-N398 WeakPolarHBondContact CA-OD1 3.25Å; C359-N398 WeakPolarHBondContact CB-OD1 3.44Å; C359-N398 PolarHBondContact O-OD1 3.42Å; L394-N398 PolarHBondContact O-ND2 3.16Å; L395-N398 PolarHBondContact O-N 2.82Å; L395-N398 PolarHBondContact O-ND2 3.43Å; S396-N398 PolarHBondContact O-N 2.97Å; S396-N398 VanDerWaalsContact O-N 3.16Å; N398-A400 PolarHBondContact O-N 3.4Å; N398-I401 PolarHBondContact O-N 3.09Å; N398-V402 VanDerWaalsContact O-CG2 3.29Å; N398-V402 WeakPolarHBondContact O-CG2 3.32Å; N398-V402 PolarHBondContact O-N 2.86Å
399	W	87.4	Confident	91.8	Very high	113 Å²	113	28.6 Å²	28.6	43%	0.428	15%	0.15	S	C	.	.	H	α-helix	trans	-57.2	-54.5	-164.2	-78.8	91.8	0	0	0	114.4	F280 V337	F280-W399 AromaticContact CE2-CD2 3.98Å; F280-W399 HydrophobicContact CE2-CD2 3.98Å; F280-W399 AromaticContact CE2-CE3 3.69Å; F280-W399 HydrophobicContact CE2-CE3 3.69Å; F280-W399 HydrophobicContact CE2-CH2 4.39Å; F280-W399 AromaticContact CE2-CZ3 3.92Å; F280-W399 HydrophobicContact CE2-CZ3 3.92Å; F280-W399 HydrophobicContact CZ-CD2 4.35Å; F280-W399 AromaticContact CZ-CE3 3.61Å; F280-W399 HydrophobicContact CZ-CE3 3.61Å; F280-W399 HydrophobicContact CZ-CH2 4.05Å; F280-W399 AromaticContact CZ-CZ3 3.45Å; F280-W399 HydrophobicContact CZ-CZ3 3.45Å; F280-W399 VanDerWaalsContact CZ-CZ3 3.45Å; V337-W399 HydrophobicContact CG2-CB 4.39Å
400	A	87.1	Confident	91.2	Very high	32 Å²	32	25.4 Å²	25.4	26%	0.264	14%	0.136	S	C	.	.	H	α-helix	trans	-70.8	-35.9	-178	0	0	0	0	0	112.3	V337 V341 N398 A403 D404	V337-A400 HydrophobicContact CG1-CB 4.09Å; V341-A400 HydrophobicContact CG2-CB 3.49Å; V341-A400 VanDerWaalsContact CG2-CB 3.49Å; N398-A400 PolarHBondContact O-N 3.4Å; A400-A403 PolarHBondContact O-N 2.66Å; A400-D404 PolarHBondContact O-N 3.17Å
401	I	91.3	Very high	90.4	Very high	2 Å²	2	23.8 Å²	23.8	1%	0.01	13%	0.128	C	C	.	.	H	α-helix	trans	-70.8	-37.5	-175.7	-53.3	175.5	0	0	0	111	G340 D355 V358 C359 M397 N398 A403 D404 I405	G340-I401 WeakPolarHBondContact O-CD1 3.45Å; D355-I401 HydrophobicContact CB-CG2 3.55Å; D355-I401 WeakPolarHBondContact O-CG2 3.42Å; V358-I401 HydrophobicContact CB-CD1 3.98Å; V358-I401 HydrophobicContact CG1-CD1 3.44Å; V358-I401 VanDerWaalsContact CG1-CD1 3.44Å; C359-I401 VanDerWaalsContact SG-CG2 3.52Å; M397-I401 WeakPolarHBondContact O-CD1 3.4Å; N398-I401 PolarHBondContact O-N 3.09Å; I401-A403 VanDerWaalsContact C-N 3.33Å; I401-A403 PolarHBondContact O-N 3.11Å; I401-D404 WeakPolarHBondContact O-CB 3.16Å; I401-D404 PolarHBondContact O-N 2.98Å; I401-I405 HydrophobicContact CG2-CD1 4.19Å; I401-I405 HydrophobicContact CG2-CG1 4.48Å; I401-I405 WeakPolarHBondContact O-CG1 3.42Å; I401-I405 PolarHBondContact O-N 3.4Å
402	V	91.5	Very high	89.3	Confident	2 Å²	2	26.2 Å²	26.2	1%	0.012	14%	0.144	C	C	.	.	H	α-helix	trans	-62.6	-41	176.6	170.8	0	0	0	0	111.6	F280 N398 I405 L406 Q422 F478	F280-V402 HydrophobicContact CB-CG1 3.8Å; F280-V402 HydrophobicContact CB-CG2 4.29Å; F280-V402 HydrophobicContact CD1-CG1 4.39Å; F280-V402 HydrophobicContact CD2-CB 4.1Å; F280-V402 HydrophobicContact CD2-CG1 3.92Å; F280-V402 HydrophobicContact CD2-CG2 4.02Å; F280-V402 HydrophobicContact CG-CB 4.46Å; F280-V402 HydrophobicContact CG-CG1 3.79Å; F280-V402 HydrophobicContact CG-CG2 4.47Å; N398-V402 VanDerWaalsContact O-CG2 3.29Å; N398-V402 WeakPolarHBondContact O-CG2 3.32Å; N398-V402 PolarHBondContact O-N 2.86Å; V402-I405 WeakPolarHBondContact O-CB 3.28Å; V402-I405 PolarHBondContact O-N 3.06Å; V402-L406 PolarHBondContact O-N 3.04Å; V402-Q422 VanDerWaalsContact CG1-NE2 3.29Å; V402-F478 HydrophobicContact CG2-CE1 3.71Å; V402-F478 HydrophobicContact CG2-CZ 3.58Å
403	A	86.1	Confident	88.2	Confident	51 Å²	51	27.4 Å²	27.4	42%	0.421	15%	0.153	S	C	.	.	H	α-helix	trans	-61.9	-44.1	174.9	0	0	0	0	0	111.1	A400 I401 I405 L406 L407	A400-A403 PolarHBondContact O-N 2.66Å; I401-A403 VanDerWaalsContact C-N 3.33Å; I401-A403 PolarHBondContact O-N 3.11Å; A403-I405 PolarHBondContact O-N 2.86Å; A403-L406 PolarHBondContact O-N 3.32Å; A403-L407 WeakPolarHBondContact O-CG 3.42Å; A403-L407 PolarHBondContact O-N 3.09Å
404	D	85.4	Confident	87.3	Confident	61 Å²	61	27.4 Å²	27.4	33%	0.326	15%	0.151	S	C	.	.	H	α-helix	trans	-57.3	-46.6	173.6	-90.8	10.3	0	0	0	111.9	R348 A400 I401 L406 L407 Y408	R348-D404 IonicContact CZ-OD2 3.36Å; R348-D404 IonicContact NH1-OD2 2.89Å; R348-D404 PolarHBondContact NH1-OD2 3.14Å; R348-D404 IonicContact NH2-OD2 3.08Å; A400-D404 PolarHBondContact O-N 3.17Å; I401-D404 WeakPolarHBondContact O-CB 3.16Å; I401-D404 PolarHBondContact O-N 2.98Å; D404-L406 VanDerWaalsContact C-N 3.31Å; D404-L406 PolarHBondContact O-N 3.33Å; D404-L407 PolarHBondContact O-N 3.48Å; D404-L407 VanDerWaalsContact O-N 3.13Å; D404-Y408 WeakPolarHBondContact O-CD1 3.15Å; D404-Y408 VanDerWaalsContact O-CE1 3.29Å; D404-Y408 WeakPolarHBondContact O-CE1 3.44Å; D404-Y408 PolarHBondContact O-N 3.49Å
405	I	91.3	Very high	86.4	Confident	0 Å²	0	28.8 Å²	28.8	0%	0	15%	0.153	C	C	.	.	H	α-helix	trans	-53	-49.4	179	-72.4	163.9	0	0	0	110.8	D355 P356 I401 V402 A403 L407 Y408 V409 T481 I485	D355-I405 HydrophobicContact CB-CD1 4.27Å; D355-I405 HydrophobicContact CB-CG1 3.92Å; P356-I405 HydrophobicContact CB-CD1 4.26Å; I401-I405 HydrophobicContact CG2-CD1 4.19Å; I401-I405 HydrophobicContact CG2-CG1 4.48Å; I401-I405 WeakPolarHBondContact O-CG1 3.42Å; I401-I405 PolarHBondContact O-N 3.4Å; V402-I405 WeakPolarHBondContact O-CB 3.28Å; V402-I405 PolarHBondContact O-N 3.06Å; A403-I405 PolarHBondContact O-N 2.86Å; I405-L407 VanDerWaalsContact C-N 3.3Å; I405-L407 PolarHBondContact O-N 3.23Å; I405-Y408 VanDerWaalsContact CA-CE1 3.47Å; I405-Y408 HydrophobicContact CG1-CE1 4.43Å; I405-Y408 VanDerWaalsContact CG1-OH 3.32Å; I405-Y408 WeakPolarHBondContact CG1-OH 3.14Å; I405-Y408 PolarHBondContact O-N 3.25Å; I405-V409 HydrophobicContact CG2-CG1 4.46Å; I405-V409 WeakPolarHBondContact O-CG1 3Å; I405-V409 VanDerWaalsContact O-CG2 3.23Å; I405-V409 WeakPolarHBondContact O-CG2 3.17Å; I405-V409 PolarHBondContact O-N 2.68Å; I405-T481 HydrophobicContact CG2-CG2 4.48Å; I405-I485 HydrophobicContact CG2-CD1 3.88Å
406	L	89.3	Confident	85.2	Confident	1 Å²	1	33 Å²	33	1%	0.005	18%	0.183	C	C	.	.	H	α-helix	trans	-56.5	-45.5	-180	-176.3	153.7	0	0	0	111.6	F273 V402 A403 D404 Y408 V409 V410 R415 A418 E419	F273-L406 HydrophobicContact CD2-CD1 4.42Å; F273-L406 HydrophobicContact CE2-CD1 3.92Å; F273-L406 HydrophobicContact CE2-CG 4.44Å; V402-L406 PolarHBondContact O-N 3.04Å; A403-L406 PolarHBondContact O-N 3.32Å; D404-L406 VanDerWaalsContact C-N 3.31Å; D404-L406 PolarHBondContact O-N 3.33Å; L406-Y408 VanDerWaalsContact C-N 3.31Å; L406-Y408 PolarHBondContact O-N 2.89Å; L406-V409 PolarHBondContact O-N 3.4Å; L406-V410 HydrophobicContact CG-CG2 4.31Å; L406-V410 WeakPolarHBondContact O-CB 3.33Å; L406-V410 WeakPolarHBondContact O-CG2 3.49Å; L406-V410 PolarHBondContact O-N 3.23Å; L406-R415 HydrophobicContact CD2-CB 4.35Å; L406-R415 HydrophobicContact CD2-CG 4.33Å; L406-A418 HydrophobicContact CD1-CB 4.07Å; L406-A418 HydrophobicContact CD2-CB 4.32Å; L406-A418 HydrophobicContact CG-CB 4.28Å; L406-E419 HydrophobicContact CD1-CB 4.32Å; L406-E419 HydrophobicContact CD1-CG 3.63Å; L406-E419 HydrophobicContact CD2-CG 3.65Å; L406-E419 HydrophobicContact CG-CG 4.3Å
407	L	82.7	Confident	84.6	Confident	64 Å²	64	34.1 Å²	34.1	34%	0.335	19%	0.189	S	C	.	.	H	α-helix	trans	-62.7	-34.9	-173.3	-67.3	176.6	0	0	0	112.9	A403 D404 I405 R415	A403-L407 WeakPolarHBondContact O-CG 3.42Å; A403-L407 PolarHBondContact O-N 3.09Å; D404-L407 PolarHBondContact O-N 3.48Å; D404-L407 VanDerWaalsContact O-N 3.13Å; I405-L407 VanDerWaalsContact C-N 3.3Å; I405-L407 PolarHBondContact O-N 3.23Å; L407-R415 PolarHBondContact O-NE 3.06Å; L407-R415 PolarHBondContact O-NH2 3.3Å
408	Y	85.2	Confident	84.1	Confident	38 Å²	38	33.4 Å²	33.4	15%	0.149	19%	0.186	C	C	.	.	H	α-helix	trans	-99	-9.7	-177.8	65.7	-108.3	0	0	0	114.8	D355 D404 I405 L406 I485 R489	D355-Y408 WeakPolarHBondContact CB-OH 3.21Å; D355-Y408 WeakPolarHBondContact OD2-CE1 3.5Å; D355-Y408 PolarHBondContact OD2-OH 2.52Å; D404-Y408 WeakPolarHBondContact O-CD1 3.15Å; D404-Y408 VanDerWaalsContact O-CE1 3.29Å; D404-Y408 WeakPolarHBondContact O-CE1 3.44Å; D404-Y408 PolarHBondContact O-N 3.49Å; I405-Y408 VanDerWaalsContact CA-CE1 3.47Å; I405-Y408 HydrophobicContact CG1-CE1 4.43Å; I405-Y408 VanDerWaalsContact CG1-OH 3.32Å; I405-Y408 WeakPolarHBondContact CG1-OH 3.14Å; I405-Y408 PolarHBondContact O-N 3.25Å; L406-Y408 VanDerWaalsContact C-N 3.31Å; L406-Y408 PolarHBondContact O-N 2.89Å; Y408-I485 HydrophobicContact CE2-CD1 3.66Å; Y408-I485 HydrophobicContact CE2-CG1 3.69Å; Y408-R489 HydrophobicContact CD2-CB 4.12Å; Y408-R489 HydrophobicContact CD2-CG 3.88Å
409	V	89.3	Confident	83.6	Confident	3 Å²	3	37.2 Å²	37.2	2%	0.018	20%	0.204	C	C	.	.	H	α-helix	trans	-97	-17.6	172	-56.4	0	0	0	0	113.3	N270 F273 I405 L406 I485 D488	N270-V409 PolarHBondContact ND2-O 2.99Å; F273-V409 HydrophobicContact CB-CG2 4.47Å; I405-V409 HydrophobicContact CG2-CG1 4.46Å; I405-V409 WeakPolarHBondContact O-CG1 3Å; I405-V409 VanDerWaalsContact O-CG2 3.23Å; I405-V409 WeakPolarHBondContact O-CG2 3.17Å; I405-V409 PolarHBondContact O-N 2.68Å; L406-V409 PolarHBondContact O-N 3.4Å; V409-I485 HydrophobicContact CG1-CD1 3.42Å; V409-I485 VanDerWaalsContact CG1-CD1 3.42Å; V409-I485 HydrophobicContact CG1-CG1 4.34Å; V409-D488 HydrophobicContact CB-CB 4.33Å; V409-D488 HydrophobicContact CG1-CB 4.32Å
410	V	84.3	Confident	83.4	Confident	4 Å²	4	34.3 Å²	34.3	2%	0.024	20%	0.204	C	C	.	.	S	Bend	trans	-110.6	132.4	178.2	-175.3	0	0	0	0	110.6	L267 F273 L406 R414 R415 A418	L267-V410 HydrophobicContact CD2-CG1 3.86Å; L267-V410 HydrophobicContact CD2-CG2 4.03Å; F273-V410 HydrophobicContact CB-CG2 4.47Å; F273-V410 HydrophobicContact CD2-CG2 4.01Å; F273-V410 HydrophobicContact CG-CG2 4.39Å; L406-V410 HydrophobicContact CG-CG2 4.31Å; L406-V410 WeakPolarHBondContact O-CB 3.33Å; L406-V410 WeakPolarHBondContact O-CG2 3.49Å; L406-V410 PolarHBondContact O-N 3.23Å; V410-R414 HydrophobicContact CG1-CB 3.74Å; V410-R415 HydrophobicContact CB-CG 4.18Å; V410-R415 HydrophobicContact CG1-CG 4.13Å; V410-R415 PolarHBondContact O-NE 3.32Å; V410-A418 HydrophobicContact CB-CB 4.47Å; V410-A418 HydrophobicContact CG1-CB 3.98Å; V410-A418 HydrophobicContact CG2-CB 4.05Å
411	I	81.6	Confident	83.4	Confident	21 Å²	21	37 Å²	37	11%	0.108	21%	0.21	C	C	.	.			trans	-63.7	146.8	176.8	60.5	173.4	0	0	0	111.5	T413 R414 R415 A492 H495	I411-T413 VanDerWaalsContact C-N 3.27Å; I411-T413 VanDerWaalsContact CD1-OG1 3.3Å; I411-T413 WeakPolarHBondContact CD1-OG1 3.5Å; I411-T413 PolarHBondContact O-N 3.49Å; I411-T413 VanDerWaalsContact O-N 3.09Å; I411-R414 HydrophobicContact CD1-CG 4.08Å; I411-R414 HydrophobicContact CG1-CB 4.05Å; I411-R414 HydrophobicContact CG1-CG 3.9Å; I411-R414 PolarHBondContact O-N 2.93Å; I411-R415 WeakPolarHBondContact O-CG 3.17Å; I411-R415 PolarHBondContact O-N 3.4Å; I411-A492 HydrophobicContact CG2-CB 4.25Å; I411-H495 HydrophobicContact CG2-CB 3.88Å
412	P	74.6	Confident	83.4	Confident	52 Å²	52	37.4 Å²	37.4	34%	0.338	21%	0.212	S	C	.	.	G	3₁₀ helix	trans	-51.1	-39.1	-174	-29.8	35	0	0	0	115.5	L255 R414 R415 M496	L255-P412 HydrophobicContact CD1-CB 4.42Å; P412-R414 PolarHBondContact O-N 3.47Å; P412-R415 PolarHBondContact O-N 3.36Å; P412-M496 HydrophobicContact CG-CE 4.09Å; P412-M496 HydrophobicContact CG-CG 4.34Å; P412-M496 HydrophobicContact CG-SD 4.12Å
413	T	72.4	Confident	83.2	Confident	49 Å²	49	41.5 Å²	41.5	30%	0.301	23%	0.233	S	C	.	.	G	3₁₀ helix	trans	-62.4	-22.4	179.4	48.5	0	0	0	0	114.4	L255 I411	L255-T413 HydrophobicContact CB-CG2 3.41Å; L255-T413 VanDerWaalsContact CB-CG2 3.41Å; L255-T413 HydrophobicContact CD1-CG2 3.67Å; L255-T413 HydrophobicContact CD2-CG2 3.87Å; L255-T413 HydrophobicContact CG-CG2 3.83Å; I411-T413 VanDerWaalsContact C-N 3.27Å; I411-T413 VanDerWaalsContact CD1-OG1 3.3Å; I411-T413 WeakPolarHBondContact CD1-OG1 3.5Å; I411-T413 PolarHBondContact O-N 3.49Å; I411-T413 VanDerWaalsContact O-N 3.09Å
414	R	77.9	Confident	83.4	Confident	13 Å²	13	42.2 Å²	42.2	5%	0.049	23%	0.232	C	C	.	.	G	3₁₀ helix	trans	-111.7	-5.9	-174.3	-64	-177.3	176.5	148.7	-0.2	113.8	D263 A266 V410 I411 P412 S416 T417 A418 E502	D263-R414 HydrophobicContact CB-CG 4.23Å; D263-R414 WeakPolarHBondContact OD1-CD 3.15Å; D263-R414 WeakPolarHBondContact OD1-CG 3.38Å; D263-R414 IonicContact OD1-CZ 2.78Å; D263-R414 IonicContact OD1-NE 3.34Å; D263-R414 PolarHBondContact OD1-NE 2.95Å; D263-R414 IonicContact OD1-NH2 3.48Å; A266-R414 VanDerWaalsContact CB-CZ 3.49Å; V410-R414 HydrophobicContact CG1-CB 3.74Å; I411-R414 HydrophobicContact CD1-CG 4.08Å; I411-R414 HydrophobicContact CG1-CB 4.05Å; I411-R414 HydrophobicContact CG1-CG 3.9Å; I411-R414 PolarHBondContact O-N 2.93Å; P412-R414 PolarHBondContact O-N 3.47Å; R414-S416 PolarHBondContact O-N 3.29Å; R414-T417 PolarHBondContact O-N 3.26Å; R414-A418 WeakPolarHBondContact O-CB 3.31Å; R414-A418 PolarHBondContact O-N 3.29Å; R414-E502 IonicContact CZ-OE1 3.62Å; R414-E502 IonicContact CZ-OE2 3.71Å; R414-E502 IonicContact NH1-OE1 3.76Å; R414-E502 PolarHBondContact NH1-OE1 2.86Å; R414-E502 IonicContact NH1-OE2 3.24Å; R414-E502 IonicContact NH2-OE1 2.71Å; R414-E502 PolarHBondContact NH2-OE1 3.47Å; R414-E502 IonicContact NH2-OE2 3.77Å; R414-E502 PolarHBondContact NH2-OE2 2.89Å
415	R	79.7	Confident	83.7	Confident	68 Å²	68	41 Å²	41	26%	0.257	23%	0.225	S	C	.	.	H	α-helix	trans	-60.1	-46	-173	-75.6	176.2	-173.9	167.1	-1.8	113.1	L406 L407 V410 I411 P412 T417 A418 E419	L406-R415 HydrophobicContact CD2-CB 4.35Å; L406-R415 HydrophobicContact CD2-CG 4.33Å; L407-R415 PolarHBondContact O-NE 3.06Å; L407-R415 PolarHBondContact O-NH2 3.3Å; V410-R415 HydrophobicContact CB-CG 4.18Å; V410-R415 HydrophobicContact CG1-CG 4.13Å; V410-R415 PolarHBondContact O-NE 3.32Å; I411-R415 WeakPolarHBondContact O-CG 3.17Å; I411-R415 PolarHBondContact O-N 3.4Å; P412-R415 PolarHBondContact O-N 3.36Å; R415-T417 VanDerWaalsContact C-N 3.35Å; R415-T417 PolarHBondContact O-N 3.22Å; R415-A418 WeakPolarHBondContact O-CB 3.35Å; R415-A418 PolarHBondContact O-N 3.08Å; R415-A418 VanDerWaalsContact O-N 3.13Å; R415-E419 WeakPolarHBondContact O-CG 3.29Å; R415-E419 PolarHBondContact O-N 3.36Å
416	S	70.1	Confident	83.8	Confident	91 Å²	91	41.2 Å²	41.2	64%	0.636	23%	0.226	S	C	*	.	H	α-helix	trans	-61.8	-42.6	179.3	178.9	0	0	0	0	112	R414 A418 E419 A420	R414-S416 PolarHBondContact O-N 3.29Å; S416-A418 VanDerWaalsContact C-N 3.33Å; S416-A418 PolarHBondContact O-N 3.48Å; S416-E419 PolarHBondContact O-N 3.14Å; S416-A420 WeakPolarHBondContact O-CB 3.48Å; S416-A420 PolarHBondContact O-N 3Å
417	T	80.6	Confident	84	Confident	36 Å²	36	42.7 Å²	42.7	22%	0.221	23%	0.233	C	C	.	.	H	α-helix	trans	-62.6	-41.1	174.3	-52.3	0	0	0	0	111.6	D263 L267 R414 R415 F421	D263-T417 HydrophobicContact CB-CG2 4.49Å; L267-T417 HydrophobicContact CD1-CG2 4.12Å; R414-T417 PolarHBondContact O-N 3.26Å; R415-T417 VanDerWaalsContact C-N 3.35Å; R415-T417 PolarHBondContact O-N 3.22Å; T417-F421 WeakPolarHBondContact O-CB 3.29Å; T417-F421 PolarHBondContact O-N 3.34Å
418	A	84.5	Confident	84.4	Confident	0 Å²	0	43.8 Å²	43.8	0%	0	24%	0.239	C	C	.	.	H	α-helix	trans	-64.6	-46.1	178	0	0	0	0	0	112.2	L267 F273 L406 V410 R414 R415 S416 F421 Q422	L267-A418 HydrophobicContact CD1-CB 3.97Å; L267-A418 HydrophobicContact CD2-CB 3.63Å; L267-A418 HydrophobicContact CG-CB 4.47Å; F273-A418 HydrophobicContact CD2-CB 4.26Å; F273-A418 HydrophobicContact CE2-CB 3.61Å; F273-A418 HydrophobicContact CZ-CB 3.89Å; F273-A418 WeakPolarHBondContact CZ-O 3.42Å; L406-A418 HydrophobicContact CD1-CB 4.07Å; L406-A418 HydrophobicContact CD2-CB 4.32Å; L406-A418 HydrophobicContact CG-CB 4.28Å; V410-A418 HydrophobicContact CB-CB 4.47Å; V410-A418 HydrophobicContact CG1-CB 3.98Å; V410-A418 HydrophobicContact CG2-CB 4.05Å; R414-A418 WeakPolarHBondContact O-CB 3.31Å; R414-A418 PolarHBondContact O-N 3.29Å; R415-A418 WeakPolarHBondContact O-CB 3.35Å; R415-A418 PolarHBondContact O-N 3.08Å; R415-A418 VanDerWaalsContact O-N 3.13Å; S416-A418 VanDerWaalsContact C-N 3.33Å; S416-A418 PolarHBondContact O-N 3.48Å; A418-F421 PolarHBondContact O-N 3.35Å; A418-Q422 WeakPolarHBondContact O-CB 3.44Å; A418-Q422 PolarHBondContact O-N 2.71Å
419	E	82.9	Confident	84.8	Confident	81 Å²	81	46.7 Å²	46.7	38%	0.379	26%	0.257	S	S	.	.	H	α-helix	trans	-61.5	-47.9	176.8	-75.3	172.3	-176.1	0	0	110.8	L406 R415 S416 F421 Q422 I423	L406-E419 HydrophobicContact CD1-CB 4.32Å; L406-E419 HydrophobicContact CD1-CG 3.63Å; L406-E419 HydrophobicContact CD2-CG 3.65Å; L406-E419 HydrophobicContact CG-CG 4.3Å; R415-E419 WeakPolarHBondContact O-CG 3.29Å; R415-E419 PolarHBondContact O-N 3.36Å; S416-E419 PolarHBondContact O-N 3.14Å; E419-F421 VanDerWaalsContact C-N 3.33Å; E419-F421 PolarHBondContact O-N 3.48Å; E419-Q422 PolarHBondContact O-N 3.26Å; E419-I423 WeakPolarHBondContact O-CB 3.24Å; E419-I423 VanDerWaalsContact O-CG1 3.26Å; E419-I423 WeakPolarHBondContact O-CG1 3.49Å; E419-I423 PolarHBondContact O-N 3.27Å
420	A	83.9	Confident	85.1	Confident	52 Å²	52	46.6 Å²	46.6	43%	0.43	26%	0.256	S	S	.	.	H	α-helix	trans	-59.1	-44.1	177.9	0	0	0	0	0	111.8	S416 I423 V424	S416-A420 WeakPolarHBondContact O-CB 3.48Å; S416-A420 PolarHBondContact O-N 3Å; A420-I423 PolarHBondContact O-N 3.2Å; A420-V424 WeakPolarHBondContact O-CG2 3.26Å; A420-V424 PolarHBondContact O-N 3.46Å
421	F	87.6	Confident	85.5	Confident	88 Å²	88	47.5 Å²	47.5	39%	0.386	26%	0.26	S	S	.	.	H	α-helix	trans	-64	-45	177	-177.7	-97.7	0	0	0	112	L264 F273 T417 A418 E419 I423 V424 L425	L264-F421 HydrophobicContact CD1-CD2 4.18Å; L264-F421 HydrophobicContact CD1-CE2 4.25Å; F273-F421 AromaticContact CE1-CD1 3.93Å; F273-F421 HydrophobicContact CE1-CD1 3.93Å; F273-F421 HydrophobicContact CE1-CE1 4.46Å; F273-F421 AromaticContact CZ-CD1 3.94Å; F273-F421 HydrophobicContact CZ-CD1 3.94Å; T417-F421 WeakPolarHBondContact O-CB 3.29Å; T417-F421 PolarHBondContact O-N 3.34Å; A418-F421 PolarHBondContact O-N 3.35Å; E419-F421 VanDerWaalsContact C-N 3.33Å; E419-F421 PolarHBondContact O-N 3.48Å; F421-I423 VanDerWaalsContact C-N 3.33Å; F421-I423 PolarHBondContact O-N 3.5Å; F421-V424 PolarHBondContact O-N 3.46Å; F421-L425 HydrophobicContact CE1-CD2 4.24Å; F421-L425 WeakPolarHBondContact O-CB 3.21Å; F421-L425 PolarHBondContact O-N 2.9Å
422	Q	90.1	Very high	86.1	Confident	11 Å²	11	46.6 Å²	46.6	5%	0.051	26%	0.256	C	S	.	.	H	α-helix	trans	-61.8	-41.7	178.8	-172.9	177.1	45.1	0	0	111.6	F273 S277 F280 V402 A418 E419 L425 S426	F273-Q422 HydrophobicContact CE2-CB 4.41Å; S277-Q422 PolarHBondContact OG-NE2 2.87Å; F280-Q422 HydrophobicContact CD1-CG 4.06Å; V402-Q422 VanDerWaalsContact CG1-NE2 3.29Å; A418-Q422 WeakPolarHBondContact O-CB 3.44Å; A418-Q422 PolarHBondContact O-N 2.71Å; E419-Q422 PolarHBondContact O-N 3.26Å; Q422-L425 PolarHBondContact O-N 2.85Å; Q422-S426 VanDerWaalsContact O-CB 3.31Å; Q422-S426 WeakPolarHBondContact O-CB 3.49Å; Q422-S426 PolarHBondContact O-N 2.9Å; Q422-S426 PolarHBondContact O-OG 3.49Å
423	I	88.3	Confident	87	Confident	88 Å²	88	45.4 Å²	45.4	45%	0.451	25%	0.253	S	S	.	.	H	α-helix	trans	-64.6	-46.1	176.6	-71.6	169	0	0	0	111.4	E419 A420 F421 L425 S426 H427	E419-I423 WeakPolarHBondContact O-CB 3.24Å; E419-I423 VanDerWaalsContact O-CG1 3.26Å; E419-I423 WeakPolarHBondContact O-CG1 3.49Å; E419-I423 PolarHBondContact O-N 3.27Å; A420-I423 PolarHBondContact O-N 3.2Å; F421-I423 VanDerWaalsContact C-N 3.33Å; F421-I423 PolarHBondContact O-N 3.5Å; I423-L425 VanDerWaalsContact C-N 3.34Å; I423-L425 PolarHBondContact O-N 3.48Å; I423-S426 PolarHBondContact O-N 3.34Å; I423-S426 PolarHBondContact O-OG 3.25Å; I423-S426 VanDerWaalsContact O-OG 3.05Å; I423-H427 WeakPolarHBondContact O-CB 3.45Å; I423-H427 PolarHBondContact O-CD2 2.97Å; I423-H427 VanDerWaalsContact O-CD2 3.3Å; I423-H427 PolarHBondContact O-N 3.42Å
424	V	90.1	Very high	88.1	Confident	66 Å²	66	43 Å²	43	40%	0.4	24%	0.239	S	C	.	.	H	α-helix	trans	-63	-43.7	178.1	168.4	0	0	0	0	110.6	M109 A420 F421 L428	M109-V424 HydrophobicContact SD-CB 4.48Å; M109-V424 HydrophobicContact SD-CG1 4.07Å; A420-V424 WeakPolarHBondContact O-CG2 3.26Å; A420-V424 PolarHBondContact O-N 3.46Å; F421-V424 PolarHBondContact O-N 3.46Å; V424-L428 WeakPolarHBondContact O-CB 3.38Å; V424-L428 PolarHBondContact O-N 2.68Å
425	L	91.9	Very high	89	Confident	36 Å²	36	42.4 Å²	42.4	19%	0.188	24%	0.237	C	C	.	.	H	α-helix	trans	-63.3	-46.3	178.4	-173	67.9	0	0	0	111.5	F421 Q422 I423 L429	F421-L425 HydrophobicContact CE1-CD2 4.24Å; F421-L425 WeakPolarHBondContact O-CB 3.21Å; F421-L425 PolarHBondContact O-N 2.9Å; Q422-L425 PolarHBondContact O-N 2.85Å; I423-L425 VanDerWaalsContact C-N 3.34Å; I423-L425 PolarHBondContact O-N 3.48Å; L425-L429 HydrophobicContact CD1-CD1 3.56Å; L425-L429 HydrophobicContact CD1-CG 4.23Å; L425-L429 HydrophobicContact CG-CD1 4.49Å; L425-L429 WeakPolarHBondContact O-CB 3.43Å; L425-L429 PolarHBondContact O-N 2.8Å
426	S	92.8	Very high	89.8	Confident	4 Å²	4	43.3 Å²	43.3	3%	0.028	24%	0.24	C	C	.	.	H	α-helix	trans	-67.9	-35.9	-178.7	69.4	0	0	0	0	112.5	A284 Q422 I423 G430 D431	A284-S426 WeakPolarHBondContact CB-O 3.19Å; Q422-S426 VanDerWaalsContact O-CB 3.31Å; Q422-S426 WeakPolarHBondContact O-CB 3.49Å; Q422-S426 PolarHBondContact O-N 2.9Å; Q422-S426 PolarHBondContact O-OG 3.49Å; I423-S426 PolarHBondContact O-N 3.34Å; I423-S426 PolarHBondContact O-OG 3.25Å; I423-S426 VanDerWaalsContact O-OG 3.05Å; S426-G430 WeakPolarHBondContact O-CA 3.44Å; S426-G430 PolarHBondContact O-N 2.95Å; S426-D431 PolarHBondContact O-N 3.02Å
427	H	92.6	Very high	91.1	Very high	32 Å²	32	42.2 Å²	42.2	15%	0.148	23%	0.227	C	C	.	.	I	π-helix	trans	-73.1	-50.2	175.3	-79.6	-52.8	0	0	0	112.3	I105 M109 I423 D431 A432	I105-H427 HydrophobicContact CG2-CB 4.27Å; M109-H427 HydrophobicContact SD-CB 3.91Å; I423-H427 WeakPolarHBondContact O-CB 3.45Å; I423-H427 PolarHBondContact O-CD2 2.97Å; I423-H427 VanDerWaalsContact O-CD2 3.3Å; I423-H427 PolarHBondContact O-N 3.42Å; H427-D431 VanDerWaalsContact CA-OD1 3.24Å; H427-D431 WeakPolarHBondContact CA-OD1 3.35Å; H427-D431 IonicContact CE1-OD1 3.15Å; H427-D431 IonicContact CE1-OD2 3.88Å; H427-D431 PolarHBondContact CE1-OD2 3.47Å; H427-D431 IonicContact CG-OD1 3.4Å; H427-D431 IonicContact ND1-OD1 2.75Å; H427-D431 PolarHBondContact ND1-OD1 3.45Å; H427-D431 IonicContact ND1-OD2 3.8Å; H427-D431 PolarHBondContact ND1-OD2 2.93Å; H427-D431 VanDerWaalsContact ND1-OD2 3.14Å; H427-A432 WeakPolarHBondContact O-CB 3.34Å; H427-A432 PolarHBondContact O-N 3.31Å
428	L	91.4	Very high	91.9	Very high	86 Å²	86	40.5 Å²	40.5	45%	0.45	22%	0.217	S	C	.	.	I	π-helix	trans	-63.1	-49	-174.7	178.9	57.6	0	0	0	112.2	M109 V424	M109-L428 HydrophobicContact CE-CB 3.96Å; M109-L428 HydrophobicContact CE-CD1 4.01Å; M109-L428 HydrophobicContact CE-CG 4.41Å; M109-L428 HydrophobicContact SD-CB 3.98Å; V424-L428 WeakPolarHBondContact O-CB 3.38Å; V424-L428 PolarHBondContact O-N 2.68Å
429	L	93.8	Very high	92.5	Very high	100 Å²	100	40.5 Å²	40.5	52%	0.524	22%	0.217	S	C	.	.	I	π-helix	trans	-94.4	-16	-176.9	-60.7	-175.5	0	0	0	113.1	T281 F285 L425	T281-L429 HydrophobicContact CG2-CB 3.69Å; F285-L429 WeakPolarHBondContact CD2-O 3.26Å; L425-L429 HydrophobicContact CD1-CD1 3.56Å; L425-L429 HydrophobicContact CD1-CG 4.23Å; L425-L429 HydrophobicContact CG-CD1 4.49Å; L425-L429 WeakPolarHBondContact O-CB 3.43Å; L425-L429 PolarHBondContact O-N 2.8Å
430	G	95.3	Very high	93.2	Very high	0 Å²	0	38.5 Å²	38.5	0%	0	21%	0.208	C	C	.	.	I	π-helix	trans	-95.1	-103.7	177.1	0	0	0	0	0	111.9	S426 A432 G433 S434	S426-G430 WeakPolarHBondContact O-CA 3.44Å; S426-G430 PolarHBondContact O-N 2.95Å; G430-A432 PolarHBondContact O-N 2.77Å; G430-G433 PolarHBondContact O-N 2.86Å; G430-S434 WeakPolarHBondContact O-CB 3.19Å; G430-S434 PolarHBondContact O-N 3.44Å; G430-S434 PolarHBondContact O-OG 3.45Å
431	D	93.3	Very high	93.9	Very high	23 Å²	23	38.5 Å²	38.5	12%	0.123	20%	0.2	C	C	.	.	I	π-helix	trans	-73.3	-24	-164.6	66.9	-10.1	0	0	0	115	I105 S426 H427 P435	I105-D431 HydrophobicContact CD1-CB 4.04Å; I105-D431 WeakPolarHBondContact CD1-O 3.5Å; S426-D431 PolarHBondContact O-N 3.02Å; H427-D431 VanDerWaalsContact CA-OD1 3.24Å; H427-D431 WeakPolarHBondContact CA-OD1 3.35Å; H427-D431 IonicContact CE1-OD1 3.15Å; H427-D431 IonicContact CE1-OD2 3.88Å; H427-D431 PolarHBondContact CE1-OD2 3.47Å; H427-D431 IonicContact CG-OD1 3.4Å; H427-D431 IonicContact ND1-OD1 2.75Å; H427-D431 PolarHBondContact ND1-OD1 3.45Å; H427-D431 IonicContact ND1-OD2 3.8Å; H427-D431 PolarHBondContact ND1-OD2 2.93Å; H427-D431 VanDerWaalsContact ND1-OD2 3.14Å; D431-P435 WeakPolarHBondContact O-CD 3.34Å; D431-P435 WeakPolarHBondContact O-CG 3.24Å
432	A	93.7	Very high	94.4	Very high	2 Å²	2	34.3 Å²	34.3	2%	0.017	18%	0.182	C	C	.	.	T	Hydrogen-bonded Turn	trans	-73.3	-47.7	172.3	0	0	0	0	0	111.4	T102 I105 H427 G430	T102-A432 WeakPolarHBondContact CA-O 3.41Å; T102-A432 WeakPolarHBondContact CB-O 3.39Å; T102-A432 VanDerWaalsContact CG2-O 3.22Å; T102-A432 WeakPolarHBondContact CG2-O 3.33Å; T102-A432 PolarHBondContact OG1-O 3.11Å; I105-A432 HydrophobicContact CB-CB 3.79Å; I105-A432 HydrophobicContact CG2-CB 3.64Å; H427-A432 WeakPolarHBondContact O-CB 3.34Å; H427-A432 PolarHBondContact O-N 3.31Å; G430-A432 PolarHBondContact O-N 2.77Å
433	G	93.1	Very high	94.7	Very high	27 Å²	27	34.6 Å²	34.6	28%	0.278	18%	0.184	S	C	.	.	H	α-helix	trans	-79.8	-34	-173.3	0	0	0	0	0	114.1	G430 L437	G430-G433 PolarHBondContact O-N 2.86Å; G433-L437 PolarHBondContact O-N 3.05Å; G433-L437 VanDerWaalsContact O-N 3.14Å
434	S	96.7	Very high	95	Very high	0 Å²	0	37.6 Å²	37.6	0%	0	19%	0.19	C	C	.	.	H	α-helix	trans	-65	-42.9	-168.9	79	0	0	0	0	114.6	F285 S289 G430 Y436 L437 I438	F285-S434 WeakPolarHBondContact O-CB 3.17Å; F285-S434 PolarHBondContact O-OG 3.17Å; S289-S434 PolarHBondContact N-OG 2.92Å; S289-S434 VanDerWaalsContact N-OG 3.15Å; S289-S434 WeakPolarHBondContact OG-CB 3.48Å; S289-S434 PolarHBondContact OG-OG 3.13Å; G430-S434 WeakPolarHBondContact O-CB 3.19Å; G430-S434 PolarHBondContact O-N 3.44Å; G430-S434 PolarHBondContact O-OG 3.45Å; S434-Y436 PolarHBondContact O-N 2.91Å; S434-L437 PolarHBondContact O-N 3.47Å; S434-I438 VanDerWaalsContact O-CG1 3.31Å; S434-I438 WeakPolarHBondContact O-CG1 3.25Å; S434-I438 PolarHBondContact O-N 3.38Å
435	P	96.1	Very high	95.3	Very high	0 Å²	0	37 Å²	37	0%	0	18%	0.184	C	C	.	.	H	α-helix	trans	-64.9	-41.3	-176.3	-20.5	34	0	0	0	112.5	Q101 L292 W293 D431 G439	Q101-P435 HydrophobicContact CB-CB 4.38Å; Q101-P435 HydrophobicContact CB-CG 4.27Å; Q101-P435 HydrophobicContact CG-CG 4.17Å; L292-P435 HydrophobicContact CB-CB 4.23Å; L292-P435 HydrophobicContact CD2-CB 3.57Å; W293-P435 PolarHBondContact NE1-O 2.92Å; D431-P435 WeakPolarHBondContact O-CD 3.34Å; D431-P435 WeakPolarHBondContact O-CG 3.24Å; P435-G439 PolarHBondContact O-N 2.96Å
436	Y	96.9	Very high	95.4	Very high	86 Å²	86	38.4 Å²	38.4	34%	0.337	19%	0.187	S	C	.	.	H	α-helix	trans	-63.8	-42.9	174.1	177	-116.6	0	0	0	112.3	S95 L99 T102 S434 I438 G439 L440	S95-Y436 VanDerWaalsContact O-CD2 3.27Å; S95-Y436 WeakPolarHBondContact O-CD2 3.13Å; L99-Y436 HydrophobicContact CD1-CD2 4.39Å; L99-Y436 HydrophobicContact CD1-CE2 4.03Å; L99-Y436 HydrophobicContact CD2-CD2 3.49Å; L99-Y436 VanDerWaalsContact CD2-CD2 3.49Å; L99-Y436 HydrophobicContact CD2-CE2 3.62Å; L99-Y436 HydrophobicContact CD2-CG 3.97Å; L99-Y436 HydrophobicContact CG-CD2 3.48Å; L99-Y436 VanDerWaalsContact CG-CD2 3.48Å; L99-Y436 HydrophobicContact CG-CE2 3.59Å; L99-Y436 HydrophobicContact CG-CG 4.37Å; T102-Y436 WeakPolarHBondContact OG1-CB 3.33Å; S434-Y436 PolarHBondContact O-N 2.91Å; Y436-I438 PolarHBondContact O-N 3.31Å; Y436-G439 PolarHBondContact O-N 3.48Å; Y436-L440 VanDerWaalsContact O-CB 3.3Å; Y436-L440 WeakPolarHBondContact O-CB 3.36Å; Y436-L440 PolarHBondContact O-N 3.33Å
437	L	97.6	Very high	95.4	Very high	69 Å²	69	48.1 Å²	48.1	36%	0.361	22%	0.223	S	C	.	.	H	α-helix	trans	-61.3	-45.8	178.2	-179.8	60.5	0	0	0	111.7	F285 G433 S434 L440 I441 L466	F285-L437 HydrophobicContact CE2-CD2 4.09Å; F285-L437 HydrophobicContact CZ-CD2 4.11Å; G433-L437 PolarHBondContact O-N 3.05Å; G433-L437 VanDerWaalsContact O-N 3.14Å; S434-L437 PolarHBondContact O-N 3.47Å; L437-L440 PolarHBondContact O-N 3.37Å; L437-I441 HydrophobicContact CD1-CD1 4.17Å; L437-I441 HydrophobicContact CD1-CG1 4.45Å; L437-I441 HydrophobicContact CG-CD1 4.12Å; L437-I441 VanDerWaalsContact O-CG1 3.3Å; L437-I441 WeakPolarHBondContact O-CG1 3.27Å; L437-I441 PolarHBondContact O-N 3.22Å; L437-L466 HydrophobicContact CD2-CD2 3.88Å; L437-L466 HydrophobicContact CG-CD2 4.26Å
438	I	97.9	Very high	95.2	Very high	0 Å²	0	51.6 Å²	51.6	0%	0	25%	0.251	C	S	.	.	H	α-helix	trans	-60.4	-47.1	176.2	-65	-65.5	0	0	0	110.6	S289 W293 S434 Y436 L440 I441 S442 L460 S463 L464 L466	S289-I438 WeakPolarHBondContact OG-CG1 3.35Å; W293-I438 HydrophobicContact CD2-CG2 4.46Å; W293-I438 HydrophobicContact CG-CG2 4.18Å; S434-I438 VanDerWaalsContact O-CG1 3.31Å; S434-I438 WeakPolarHBondContact O-CG1 3.25Å; S434-I438 PolarHBondContact O-N 3.38Å; Y436-I438 PolarHBondContact O-N 3.31Å; I438-L440 VanDerWaalsContact C-N 3.34Å; I438-L440 PolarHBondContact O-N 3.47Å; I438-I441 PolarHBondContact O-N 2.79Å; I438-S442 PolarHBondContact O-N 2.83Å; I438-L460 HydrophobicContact CG2-CD1 3.95Å; I438-S463 WeakPolarHBondContact CD1-O 3.35Å; I438-S463 WeakPolarHBondContact O-CB 3.29Å; I438-L464 HydrophobicContact CG2-CD2 3.97Å; I438-L464 HydrophobicContact CG2-CG 4.24Å; I438-L466 HydrophobicContact CD1-CB 4.05Å; I438-L466 HydrophobicContact CD1-CD2 4.2Å
439	G	97.4	Very high	95.3	Very high	0 Å²	0	51.4 Å²	51.4	0%	0	24%	0.244	C	C	.	.	H	α-helix	trans	-63.2	-38.7	178.3	0	0	0	0	0	113.3	D94 S95 P435 Y436 S442 D443	D94-G439 WeakPolarHBondContact O-CA 3.31Å; S95-G439 PolarHBondContact N-O 3.37Å; P435-G439 PolarHBondContact O-N 2.96Å; Y436-G439 PolarHBondContact O-N 3.48Å; G439-S442 PolarHBondContact O-N 3.48Å; G439-D443 WeakPolarHBondContact O-CB 3.35Å; G439-D443 PolarHBondContact O-N 3.04Å
440	L	97.5	Very high	95.3	Very high	39 Å²	39	51.4 Å²	51.4	20%	0.204	25%	0.25	C	S	.	.	H	α-helix	trans	-64.1	-41.9	176.1	-179.4	65.6	0	0	0	112.2	Y436 L437 I438 R444	Y436-L440 VanDerWaalsContact O-CB 3.3Å; Y436-L440 WeakPolarHBondContact O-CB 3.36Å; Y436-L440 PolarHBondContact O-N 3.33Å; L437-L440 PolarHBondContact O-N 3.37Å; I438-L440 VanDerWaalsContact C-N 3.34Å; I438-L440 PolarHBondContact O-N 3.47Å; L440-R444 WeakPolarHBondContact O-CB 3.46Å; L440-R444 VanDerWaalsContact O-CG 3.31Å; L440-R444 WeakPolarHBondContact O-CG 3.32Å; L440-R444 PolarHBondContact O-N 2.8Å; L440-R444 VanDerWaalsContact O-N 3.12Å
441	I	97.5	Very high	95.1	Very high	51 Å²	51	56.7 Å²	56.7	26%	0.262	29%	0.294	S	S	.	.	H	α-helix	trans	-64.8	-44.9	175.8	-64.6	165.8	0	0	0	109.5	L437 I438 D443 R444 L445 S463 L466	L437-I441 HydrophobicContact CD1-CD1 4.17Å; L437-I441 HydrophobicContact CD1-CG1 4.45Å; L437-I441 HydrophobicContact CG-CD1 4.12Å; L437-I441 VanDerWaalsContact O-CG1 3.3Å; L437-I441 WeakPolarHBondContact O-CG1 3.27Å; L437-I441 PolarHBondContact O-N 3.22Å; I438-I441 PolarHBondContact O-N 2.79Å; I441-D443 PolarHBondContact O-N 3.02Å; I441-R444 PolarHBondContact O-N 3.33Å; I441-L445 HydrophobicContact CG2-CD1 4.09Å; I441-L445 HydrophobicContact CG2-CG 4.46Å; I441-L445 WeakPolarHBondContact O-CG 3.17Å; I441-L445 PolarHBondContact O-N 3.14Å; I441-S463 WeakPolarHBondContact CG2-OG 3.27Å; I441-L466 HydrophobicContact CD1-CD2 3.83Å
442	S	97.6	Very high	95	Very high	0 Å²	0	57.8 Å²	57.8	0%	0	30%	0.303	C	S	.	.	H	α-helix	trans	-59	-51	179.2	-174.4	0	0	0	0	111.5	D94 I438 G439 R444 L445 R446 L460 S463	D94-S442 VanDerWaalsContact OD2-CB 3.24Å; D94-S442 WeakPolarHBondContact OD2-CB 3.42Å; D94-S442 PolarHBondContact OD2-OG 3.49Å; I438-S442 PolarHBondContact O-N 2.83Å; G439-S442 PolarHBondContact O-N 3.48Å; S442-R444 VanDerWaalsContact C-N 3.31Å; S442-R444 PolarHBondContact O-N 2.97Å; S442-L445 PolarHBondContact O-N 3.48Å; S442-L445 VanDerWaalsContact O-N 3.14Å; S442-R446 WeakPolarHBondContact O-CG 3.44Å; S442-R446 PolarHBondContact O-N 3.04Å; S442-L460 PolarHBondContact OG-N 3.36Å; S442-S463 WeakPolarHBondContact CA-OG 3.25Å; S442-S463 WeakPolarHBondContact CB-OG 3.45Å; S442-S463 PolarHBondContact N-OG 3.26Å
443	D	96.6	Very high	94.9	Very high	17 Å²	17	62.7 Å²	62.7	9%	0.091	33%	0.325	C	S	.	.	H	α-helix	trans	-60	-39.1	178.2	-75.7	-8.6	0	0	0	112.9	D94 S95 G439 I441 R446 R447	D94-D443 WeakPolarHBondContact CB-OD1 3.25Å; D94-D443 PolarHBondContact N-OD1 3.01Å; D94-D443 PolarHBondContact N-OD2 2.88Å; S95-D443 WeakPolarHBondContact CB-OD2 3.2Å; S95-D443 PolarHBondContact N-OD2 3.12Å; S95-D443 PolarHBondContact OG-OD2 3.16Å; G439-D443 WeakPolarHBondContact O-CB 3.35Å; G439-D443 PolarHBondContact O-N 3.04Å; I441-D443 PolarHBondContact O-N 3.02Å; D443-R446 PolarHBondContact O-N 2.92Å; D443-R446 IonicContact OD1-CZ 2.86Å; D443-R446 IonicContact OD1-NE 2.68Å; D443-R446 PolarHBondContact OD1-NE 3.41Å; D443-R446 IonicContact OD1-NH2 3.49Å; D443-R446 PolarHBondContact OD1-NH2 3.36Å; D443-R447 WeakPolarHBondContact O-CG 3.38Å; D443-R447 PolarHBondContact O-N 2.81Å
444	R	96.1	Very high	94.9	Very high	152 Å²	152	64 Å²	64	57%	0.574	33%	0.325	S	S	*	.	H	α-helix	trans	-66	-40	176.5	-77.6	-178.1	-177	166	1.9	112.3	L440 I441 S442	L440-R444 WeakPolarHBondContact O-CB 3.46Å; L440-R444 VanDerWaalsContact O-CG 3.31Å; L440-R444 WeakPolarHBondContact O-CG 3.32Å; L440-R444 PolarHBondContact O-N 2.8Å; L440-R444 VanDerWaalsContact O-N 3.12Å; I441-R444 PolarHBondContact O-N 3.33Å; S442-R444 VanDerWaalsContact C-N 3.31Å; S442-R444 PolarHBondContact O-N 2.97Å
445	L	95.5	Very high	94.8	Very high	53 Å²	53	64.7 Å²	64.7	28%	0.277	33%	0.329	S	S	.	.	H	α-helix	trans	-64.3	-43.4	175.7	-70.7	172	0	0	0	111.2	I441 S442 R447 S448 A459 F462	I441-L445 HydrophobicContact CG2-CD1 4.09Å; I441-L445 HydrophobicContact CG2-CG 4.46Å; I441-L445 WeakPolarHBondContact O-CG 3.17Å; I441-L445 PolarHBondContact O-N 3.14Å; S442-L445 PolarHBondContact O-N 3.48Å; S442-L445 VanDerWaalsContact O-N 3.14Å; L445-R447 VanDerWaalsContact C-N 3.31Å; L445-R447 PolarHBondContact O-N 2.73Å; L445-S448 PolarHBondContact O-N 2.76Å; L445-A459 HydrophobicContact CB-CB 4.01Å; L445-F462 HydrophobicContact CD1-CB 3.96Å
446	R	93.8	Very high	94.7	Very high	66 Å²	66	67.8 Å²	67.8	25%	0.249	34%	0.344	C	S	.	.	H	α-helix	trans	-60.9	-34.6	-179.1	-69.5	-167.7	-59.2	149.3	-4.2	113.7	S442 D443 S448 W449 E456 A459	S442-R446 WeakPolarHBondContact O-CG 3.44Å; S442-R446 PolarHBondContact O-N 3.04Å; D443-R446 PolarHBondContact O-N 2.92Å; D443-R446 IonicContact OD1-CZ 2.86Å; D443-R446 IonicContact OD1-NE 2.68Å; D443-R446 PolarHBondContact OD1-NE 3.41Å; D443-R446 IonicContact OD1-NH2 3.49Å; D443-R446 PolarHBondContact OD1-NH2 3.36Å; R446-S448 PolarHBondContact O-N 3.34Å; R446-W449 PolarHBondContact O-N 2.72Å; R446-W449 VanDerWaalsContact O-N 3.09Å; R446-E456 IonicContact NH1-OE1 3.83Å; R446-A459 HydrophobicContact CG-CB 3.41Å; R446-A459 VanDerWaalsContact CG-CB 3.41Å
447	R	92.2	Very high	94.6	Very high	207 Å²	207	63.8 Å²	63.8	78%	0.781	33%	0.328	S	S	*	.	T	Hydrogen-bonded Turn	trans	-58.6	-29.2	179.8	-74.3	176.4	-171.9	172.5	2.3	113.7	D443 L445	D443-R447 WeakPolarHBondContact O-CG 3.38Å; D443-R447 PolarHBondContact O-N 2.81Å; L445-R447 VanDerWaalsContact C-N 3.31Å; L445-R447 PolarHBondContact O-N 2.73Å
448	S	89.6	Confident	94.6	Very high	106 Å²	106	65.3 Å²	65.3	74%	0.741	33%	0.329	S	S	*	.	T	Hydrogen-bonded Turn	trans	-92.3	-2.3	-177.8	-56.4	0	0	0	0	113.1	L445 R446	L445-S448 PolarHBondContact O-N 2.76Å; R446-S448 PolarHBondContact O-N 3.34Å
449	W	93.6	Very high	94.5	Very high	81 Å²	81	65.3 Å²	65.3	31%	0.307	33%	0.329	S	S	.	.	S	Bend	trans	-118.1	156.6	-171.6	-67.9	-4.1	0	0	0	111.6	R446 S455 R458 A459 F462	R446-W449 PolarHBondContact O-N 2.72Å; R446-W449 VanDerWaalsContact O-N 3.09Å; W449-S455 WeakPolarHBondContact CZ3-O 3.5Å; W449-R458 HydrophobicContact CH2-CB 3.95Å; W449-R458 HydrophobicContact CZ3-CB 3.54Å; W449-A459 HydrophobicContact CE3-CB 4.4Å; W449-A459 HydrophobicContact CZ3-CB 3.92Å; W449-F462 AromaticContact CH2-CD2 3.52Å; W449-F462 HydrophobicContact CH2-CD2 3.52Å; W449-F462 AromaticContact CH2-CE2 3.54Å; W449-F462 HydrophobicContact CH2-CE2 3.54Å; W449-F462 HydrophobicContact CZ2-CD2 4.03Å; W449-F462 AromaticContact CZ2-CE2 3.91Å; W449-F462 HydrophobicContact CZ2-CE2 3.91Å
450	P	93.2	Very high	94.5	Very high	100 Å²	100	65.3 Å²	65.3	65%	0.649	33%	0.329	S	S	*	.			trans	-64	141.7	176	26.3	-34.1	0	0	0	111	S452 S455	P450-S452 PolarHBondContact O-N 2.84Å; P450-S455 WeakPolarHBondContact O-CB 3.33Å; P450-S455 PolarHBondContact O-OG 2.95Å
451	A	90.3	Very high	94.4	Very high	111 Å²	111	64.6 Å²	64.6	92%	0.917	33%	0.325	S	S	*	.	S	Bend	trans	-64.3	106.1	176.7	0	0	0	0	0	110.3
452	S	92.6	Very high	94.4	Very high	46 Å²	46	67 Å²	67	32%	0.322	33%	0.333	S	S	.	.	S	Bend	trans	-158.5	153.5	177.7	73.4	0	0	0	0	110.6	P450 L454 S455 E456	P450-S452 PolarHBondContact O-N 2.84Å; S452-L454 PolarHBondContact O-N 2.61Å; S452-S455 WeakPolarHBondContact O-CB 3.36Å; S452-S455 PolarHBondContact O-N 2.92Å; S452-S455 PolarHBondContact OG-N 2.94Å; S452-S455 VanDerWaalsContact OG-N 3.08Å; S452-S455 PolarHBondContact OG-OG 2.87Å; S452-E456 PolarHBondContact O-N 3.02Å
453	F	91.6	Very high	94.3	Very high	106 Å²	106	67 Å²	67	47%	0.465	33%	0.334	S	S	.	.	H	α-helix	trans	-57.2	-33.1	173.9	-60.5	-61.5	0	0	0	112.3	V303 V304 P310 E456 F457	V303-F453 HydrophobicContact CG1-CB 4.22Å; V303-F453 HydrophobicContact CG1-CD1 4.25Å; V303-F453 HydrophobicContact CG1-CD2 4.37Å; V303-F453 HydrophobicContact CG1-CG 4.03Å; V304-F453 HydrophobicContact CG2-CB 4.31Å; P310-F453 HydrophobicContact CB-CD1 4.45Å; P310-F453 HydrophobicContact CB-CE1 3.71Å; P310-F453 HydrophobicContact CB-CE2 4.01Å; P310-F453 HydrophobicContact CB-CZ 3.45Å; P310-F453 VanDerWaalsContact CB-CZ 3.45Å; P310-F453 HydrophobicContact CG-CE2 4.13Å; P310-F453 HydrophobicContact CG-CZ 3.89Å; F453-E456 PolarHBondContact O-N 3.48Å; F453-F457 WeakPolarHBondContact O-CB 3.3Å; F453-F457 PolarHBondContact O-N 3.4Å
454	L	93.6	Very high	94.4	Very high	54 Å²	54	66.3 Å²	66.3	28%	0.283	33%	0.33	S	S	.	.	H	α-helix	trans	-65	-40.8	174.9	-178.9	65	0	0	0	112	V304 S452 F457 R458	V304-L454 HydrophobicContact CG1-CD1 3.74Å; S452-L454 PolarHBondContact O-N 2.61Å; L454-F457 HydrophobicContact CD1-CD1 4.5Å; L454-R458 HydrophobicContact CD1-CG 4.35Å; L454-R458 WeakPolarHBondContact O-CB 3.41Å; L454-R458 WeakPolarHBondContact O-CG 3.47Å; L454-R458 PolarHBondContact O-N 2.66Å
455	S	94.4	Very high	94.3	Very high	14 Å²	14	62.6 Å²	62.6	10%	0.098	32%	0.32	C	S	.	.	H	α-helix	trans	-65.2	-41.8	176.2	-60.8	0	0	0	0	111.5	W449 P450 S452 R458 A459	W449-S455 WeakPolarHBondContact CZ3-O 3.5Å; P450-S455 WeakPolarHBondContact O-CB 3.33Å; P450-S455 PolarHBondContact O-OG 2.95Å; S452-S455 WeakPolarHBondContact O-CB 3.36Å; S452-S455 PolarHBondContact O-N 2.92Å; S452-S455 PolarHBondContact OG-N 2.94Å; S452-S455 VanDerWaalsContact OG-N 3.08Å; S452-S455 PolarHBondContact OG-OG 2.87Å; S455-R458 PolarHBondContact O-N 3.27Å; S455-A459 VanDerWaalsContact O-CB 3.26Å; S455-A459 WeakPolarHBondContact O-CB 3.36Å; S455-A459 PolarHBondContact O-N 3.43Å
456	E	92.9	Very high	94.4	Very high	66 Å²	66	62.3 Å²	62.3	31%	0.308	32%	0.319	S	S	.	.	H	α-helix	trans	-64.4	-45.8	177.1	-69.2	177.6	177	0	0	112.3	R446 S452 F453 L460	R446-E456 IonicContact NH1-OE1 3.83Å; S452-E456 PolarHBondContact O-N 3.02Å; F453-E456 PolarHBondContact O-N 3.48Å; E456-L460 PolarHBondContact O-N 3.28Å
457	F	95.4	Very high	94.5	Very high	1 Å²	1	59.3 Å²	59.3	0%	0.004	31%	0.308	C	S	.	.	H	α-helix	trans	-59.3	-50.6	174.1	167	-105.2	0	0	0	111.7	F297 R300 S301 V304 A377 R378 F453 L454 A459 L460 Q461	F297-F457 HydrophobicContact CD2-CD2 4.31Å; F297-F457 HydrophobicContact CD2-CE2 4.1Å; F297-F457 AromaticContact CE2-CD2 3.94Å; F297-F457 HydrophobicContact CE2-CD2 3.94Å; F297-F457 AromaticContact CE2-CE2 3.37Å; F297-F457 HydrophobicContact CE2-CE2 3.37Å; F297-F457 HydrophobicContact CE2-CZ 4.09Å; F297-F457 AromaticContact CZ-CE2 3.63Å; F297-F457 HydrophobicContact CZ-CE2 3.63Å; F297-F457 HydrophobicContact CZ-CZ 4.13Å; R300-F457 HydrophobicContact CB-CB 4.26Å; R300-F457 HydrophobicContact CB-CD2 4.28Å; S301-F457 VanDerWaalsContact CB-CE2 3.48Å; S301-F457 WeakPolarHBondContact OG-CE2 3.49Å; V304-F457 HydrophobicContact CG2-CB 3.82Å; V304-F457 HydrophobicContact CG2-CD1 4.48Å; V304-F457 HydrophobicContact CG2-CG 4.23Å; A377-F457 HydrophobicContact CB-CE2 4.09Å; A377-F457 HydrophobicContact CB-CZ 3.9Å; R378-F457 HydrophobicContact CB-CE1 4.19Å; R378-F457 HydrophobicContact CB-CZ 4.37Å; F453-F457 WeakPolarHBondContact O-CB 3.3Å; F453-F457 PolarHBondContact O-N 3.4Å; L454-F457 HydrophobicContact CD1-CD1 4.5Å; F457-A459 PolarHBondContact O-N 2.82Å; F457-L460 PolarHBondContact O-N 2.87Å; F457-Q461 WeakPolarHBondContact O-CB 3.44Å; F457-Q461 PolarHBondContact O-N 3.37Å
458	R	96.3	Very high	94.6	Very high	101 Å²	101	50.1 Å²	50.1	38%	0.381	28%	0.276	S	S	.	.	H	α-helix	trans	-65.9	-35	-178	-80.3	-177.6	168.6	-177.1	-5.2	113.3	W449 L454 S455 Q461 F462	W449-R458 HydrophobicContact CH2-CB 3.95Å; W449-R458 HydrophobicContact CZ3-CB 3.54Å; L454-R458 HydrophobicContact CD1-CG 4.35Å; L454-R458 WeakPolarHBondContact O-CB 3.41Å; L454-R458 WeakPolarHBondContact O-CG 3.47Å; L454-R458 PolarHBondContact O-N 2.66Å; S455-R458 PolarHBondContact O-N 3.27Å; R458-Q461 WeakPolarHBondContact O-CB 3.17Å; R458-Q461 PolarHBondContact O-N 2.83Å; R458-F462 WeakPolarHBondContact O-CG 3.22Å; R458-F462 PolarHBondContact O-N 3.47Å
459	A	96.9	Very high	94.9	Very high	0 Å²	0	51.1 Å²	51.1	0%	0	27%	0.267	C	S	.	.	H	α-helix	trans	-66.1	-44.7	-180	0	0	0	0	0	110.2	L445 R446 W449 S455 F457 S463	L445-A459 HydrophobicContact CB-CB 4.01Å; R446-A459 HydrophobicContact CG-CB 3.41Å; R446-A459 VanDerWaalsContact CG-CB 3.41Å; W449-A459 HydrophobicContact CE3-CB 4.4Å; W449-A459 HydrophobicContact CZ3-CB 3.92Å; S455-A459 VanDerWaalsContact O-CB 3.26Å; S455-A459 WeakPolarHBondContact O-CB 3.36Å; S455-A459 PolarHBondContact O-N 3.43Å; F457-A459 PolarHBondContact O-N 2.82Å; A459-S463 WeakPolarHBondContact O-CB 3.21Å; A459-S463 PolarHBondContact O-N 3.42Å; A459-S463 PolarHBondContact O-OG 3.22Å
460	L	96.8	Very high	95.1	Very high	0 Å²	0	48.6 Å²	48.6	0%	0	26%	0.261	C	S	.	.	H	α-helix	trans	-67.4	-40.1	174.5	-173.2	60.7	0	0	0	111.6	W293 F297 I438 S442 E456 F457 F462 S463 L464	W293-L460 HydrophobicContact CB-CD1 4.43Å; W293-L460 HydrophobicContact CD2-CD1 3.81Å; W293-L460 HydrophobicContact CE3-CD1 3.65Å; W293-L460 HydrophobicContact CE3-CD2 3.91Å; W293-L460 HydrophobicContact CE3-CG 4.46Å; W293-L460 HydrophobicContact CG-CD1 4.17Å; W293-L460 HydrophobicContact CZ3-CD1 4.21Å; F297-L460 HydrophobicContact CB-CD2 3.9Å; F297-L460 HydrophobicContact CD2-CD2 4.3Å; F297-L460 HydrophobicContact CD2-CG 4.32Å; I438-L460 HydrophobicContact CG2-CD1 3.95Å; S442-L460 PolarHBondContact OG-N 3.36Å; E456-L460 PolarHBondContact O-N 3.28Å; F457-L460 PolarHBondContact O-N 2.87Å; L460-F462 PolarHBondContact O-N 3.03Å; L460-S463 PolarHBondContact O-N 3.39Å; L460-L464 HydrophobicContact CD1-CD1 4.34Å; L460-L464 HydrophobicContact CD1-CG 4.31Å; L460-L464 HydrophobicContact CG-CD1 4.01Å; L460-L464 HydrophobicContact CG-CG 4.42Å; L460-L464 WeakPolarHBondContact O-CB 3.29Å; L460-L464 WeakPolarHBondContact O-CG 3.21Å; L460-L464 PolarHBondContact O-N 3.44Å
461	Q	96.7	Very high	95.2	Very high	24 Å²	24	43.9 Å²	43.9	11%	0.112	23%	0.23	C	C	.	.	H	α-helix	trans	-54.6	-52.8	175.3	-169.1	-175.8	26.8	0	0	111.8	F297 L374 F457 R458 S463 L464 M465	F297-Q461 HydrophobicContact CE2-CB 3.81Å; F297-Q461 HydrophobicContact CE2-CG 4.04Å; F297-Q461 HydrophobicContact CZ-CG 4.27Å; L374-Q461 HydrophobicContact CB-CG 4.36Å; L374-Q461 PolarHBondContact O-NE2 2.73Å; F457-Q461 WeakPolarHBondContact O-CB 3.44Å; F457-Q461 PolarHBondContact O-N 3.37Å; R458-Q461 WeakPolarHBondContact O-CB 3.17Å; R458-Q461 PolarHBondContact O-N 2.83Å; Q461-S463 VanDerWaalsContact C-N 3.32Å; Q461-S463 PolarHBondContact O-N 2.94Å; Q461-L464 PolarHBondContact O-N 3.16Å; Q461-M465 WeakPolarHBondContact O-CG 2.91Å; Q461-M465 PolarHBondContact O-N 3.27Å
462	F	95.8	Very high	95.5	Very high	101 Å²	101	40.3 Å²	40.3	44%	0.443	20%	0.201	S	C	.	.	H	α-helix	trans	-67.5	-33.9	179	-69.2	-27.6	0	0	0	112.6	L445 W449 R458 L460 M465	L445-F462 HydrophobicContact CD1-CB 3.96Å; W449-F462 AromaticContact CH2-CD2 3.52Å; W449-F462 HydrophobicContact CH2-CD2 3.52Å; W449-F462 AromaticContact CH2-CE2 3.54Å; W449-F462 HydrophobicContact CH2-CE2 3.54Å; W449-F462 HydrophobicContact CZ2-CD2 4.03Å; W449-F462 AromaticContact CZ2-CE2 3.91Å; W449-F462 HydrophobicContact CZ2-CE2 3.91Å; R458-F462 WeakPolarHBondContact O-CG 3.22Å; R458-F462 PolarHBondContact O-N 3.47Å; L460-F462 PolarHBondContact O-N 3.03Å; F462-M465 HydrophobicContact CD1-SD 3.81Å; F462-M465 WeakPolarHBondContact O-CB 3.26Å; F462-M465 PolarHBondContact O-N 3.47Å
463	S	97.3	Very high	95.7	Very high	1 Å²	1	42.7 Å²	42.7	1%	0.007	21%	0.209	C	C	.	.	H	α-helix	trans	-64.4	-45.8	176.1	-55.9	0	0	0	0	110.8	I438 I441 S442 A459 L460 Q461 M465 L466	I438-S463 WeakPolarHBondContact CD1-O 3.35Å; I438-S463 WeakPolarHBondContact O-CB 3.29Å; I441-S463 WeakPolarHBondContact CG2-OG 3.27Å; S442-S463 WeakPolarHBondContact CA-OG 3.25Å; S442-S463 WeakPolarHBondContact CB-OG 3.45Å; S442-S463 PolarHBondContact N-OG 3.26Å; A459-S463 WeakPolarHBondContact O-CB 3.21Å; A459-S463 PolarHBondContact O-N 3.42Å; A459-S463 PolarHBondContact O-OG 3.22Å; L460-S463 PolarHBondContact O-N 3.39Å; Q461-S463 VanDerWaalsContact C-N 3.32Å; Q461-S463 PolarHBondContact O-N 2.94Å; S463-M465 PolarHBondContact O-N 3.37Å; S463-L466 WeakPolarHBondContact O-CB 2.99Å; S463-L466 PolarHBondContact O-N 2.89Å; S463-L466 VanDerWaalsContact O-N 3.08Å
464	L	96.9	Very high	96	Very high	3 Å²	3	37.8 Å²	37.8	2%	0.016	19%	0.189	C	C	.	.	H	α-helix	trans	-65.6	-18.8	178.3	-73.1	170.6	0	0	0	114	W293 F297 L374 I438 L460 Q461 L466 C467	W293-L464 HydrophobicContact CB-CD1 4.34Å; W293-L464 HydrophobicContact CB-CD2 3.92Å; W293-L464 HydrophobicContact CG-CD2 4.41Å; F297-L464 HydrophobicContact CB-CD1 4.02Å; F297-L464 HydrophobicContact CD2-CD1 3.92Å; F297-L464 HydrophobicContact CG-CD1 3.91Å; L374-L464 HydrophobicContact CD1-CB 3.78Å; L374-L464 HydrophobicContact CD2-CB 3.82Å; L374-L464 HydrophobicContact CD2-CD1 3.96Å; L374-L464 HydrophobicContact CG-CB 4.48Å; I438-L464 HydrophobicContact CG2-CD2 3.97Å; I438-L464 HydrophobicContact CG2-CG 4.24Å; L460-L464 HydrophobicContact CD1-CD1 4.34Å; L460-L464 HydrophobicContact CD1-CG 4.31Å; L460-L464 HydrophobicContact CG-CD1 4.01Å; L460-L464 HydrophobicContact CG-CG 4.42Å; L460-L464 WeakPolarHBondContact O-CB 3.29Å; L460-L464 WeakPolarHBondContact O-CG 3.21Å; L460-L464 PolarHBondContact O-N 3.44Å; Q461-L464 PolarHBondContact O-N 3.16Å; L464-L466 PolarHBondContact O-N 2.93Å; L464-C467 VanDerWaalsContact O-CB 3.24Å; L464-C467 WeakPolarHBondContact O-CB 3.36Å; L464-C467 PolarHBondContact O-N 3.36Å
465	M	95.5	Very high	96.1	Very high	74 Å²	74	35.2 Å²	35.2	37%	0.365	18%	0.175	S	C	.	.	H	α-helix	trans	-61.8	-23.3	171.9	-69.1	176.8	57.1	0	0	112.5	F371 L374 Q461 F462 S463 C467 A468 F469	F371-M465 HydrophobicContact CD2-CE 4.14Å; F371-M465 HydrophobicContact CE2-CE 3.66Å; L374-M465 HydrophobicContact CD1-CG 3.99Å; Q461-M465 WeakPolarHBondContact O-CG 2.91Å; Q461-M465 PolarHBondContact O-N 3.27Å; F462-M465 HydrophobicContact CD1-SD 3.81Å; F462-M465 WeakPolarHBondContact O-CB 3.26Å; F462-M465 PolarHBondContact O-N 3.47Å; S463-M465 PolarHBondContact O-N 3.37Å; M465-C467 PolarHBondContact O-N 3.48Å; M465-A468 PolarHBondContact O-N 3.17Å; M465-A468 VanDerWaalsContact O-N 3.14Å; M465-F469 PolarHBondContact O-N 2.82Å
466	L	96.3	Very high	96.3	Very high	47 Å²	47	37 Å²	37	25%	0.246	19%	0.191	C	C	.	.	H	α-helix	trans	-57	-34.4	171.8	-177.4	60.9	0	0	0	111.7	F285 L437 I438 I441 S463 L464 A468 F469 V470	F285-L466 HydrophobicContact CE1-CD2 4.49Å; F285-L466 HydrophobicContact CE1-CG 4.38Å; F285-L466 HydrophobicContact CZ-CD2 3.95Å; F285-L466 HydrophobicContact CZ-CG 4.27Å; L437-L466 HydrophobicContact CD2-CD2 3.88Å; L437-L466 HydrophobicContact CG-CD2 4.26Å; I438-L466 HydrophobicContact CD1-CB 4.05Å; I438-L466 HydrophobicContact CD1-CD2 4.2Å; I441-L466 HydrophobicContact CD1-CD2 3.83Å; S463-L466 WeakPolarHBondContact O-CB 2.99Å; S463-L466 PolarHBondContact O-N 2.89Å; S463-L466 VanDerWaalsContact O-N 3.08Å; L464-L466 PolarHBondContact O-N 2.93Å; L466-A468 VanDerWaalsContact C-N 3.34Å; L466-A468 PolarHBondContact O-N 3.39Å; L466-F469 HydrophobicContact CD1-CD1 4.42Å; L466-F469 PolarHBondContact O-N 2.84Å; L466-V470 HydrophobicContact CD1-CG2 4.07Å; L466-V470 HydrophobicContact CG-CG2 4.14Å; L466-V470 WeakPolarHBondContact O-CG2 3.33Å; L466-V470 PolarHBondContact O-N 2.83Å
467	C	96.3	Very high	96.5	Very high	2 Å²	2	34.6 Å²	34.6	1%	0.014	18%	0.182	C	C	.	.	H	α-helix	trans	-61.5	-40.5	177.4	-63.8	0	0	0	0	112.1	V286 S289 L464 M465 F469 G471	V286-C467 HydrophobicContact CG1-CB 4.29Å; V286-C467 HydrophobicContact CG2-CB 4.15Å; V286-C467 VanDerWaalsContact CG2-O 3.3Å; V286-C467 WeakPolarHBondContact CG2-O 3.41Å; S289-C467 VanDerWaalsContact CB-SG 3.51Å; L464-C467 VanDerWaalsContact O-CB 3.24Å; L464-C467 WeakPolarHBondContact O-CB 3.36Å; L464-C467 PolarHBondContact O-N 3.36Å; M465-C467 PolarHBondContact O-N 3.48Å; C467-F469 VanDerWaalsContact C-N 3.35Å; C467-G471 PolarHBondContact O-N 2.96Å
468	A	94.6	Very high	96.6	Very high	14 Å²	14	34.5 Å²	34.5	12%	0.116	18%	0.182	C	C	.	.	H	α-helix	trans	-65.5	-39.8	177.4	0	0	0	0	0	111.5	A367 F371 M465 L466 A472	A367-A468 WeakPolarHBondContact CB-O 3.44Å; F371-A468 HydrophobicContact CB-CB 4.3Å; M465-A468 PolarHBondContact O-N 3.17Å; M465-A468 VanDerWaalsContact O-N 3.14Å; L466-A468 VanDerWaalsContact C-N 3.34Å; L466-A468 PolarHBondContact O-N 3.39Å; A468-A472 PolarHBondContact O-N 3.06Å
469	F	95.4	Very high	96.7	Very high	128 Å²	128	33.5 Å²	33.5	56%	0.561	18%	0.183	S	C	*	.	H	α-helix	trans	-66.6	-48.3	176.4	179.3	-103.9	0	0	0	112.3	M465 L466 C467 G471 A472 L473	M465-F469 PolarHBondContact O-N 2.82Å; L466-F469 HydrophobicContact CD1-CD1 4.42Å; L466-F469 PolarHBondContact O-N 2.84Å; C467-F469 VanDerWaalsContact C-N 3.35Å; F469-G471 VanDerWaalsContact C-N 3.31Å; F469-G471 PolarHBondContact O-N 3.44Å; F469-A472 WeakPolarHBondContact O-CB 3.48Å; F469-A472 PolarHBondContact O-N 3Å; F469-L473 HydrophobicContact CD1-CD1 4.03Å; F469-L473 HydrophobicContact CE1-CD1 3.44Å; F469-L473 VanDerWaalsContact CE1-CD1 3.44Å; F469-L473 HydrophobicContact CE1-CG 4.16Å; F469-L473 HydrophobicContact CZ-CD1 3.78Å; F469-L473 HydrophobicContact CZ-CD2 4.36Å; F469-L473 HydrophobicContact CZ-CG 4.17Å; F469-L473 PolarHBondContact O-N 3.38Å
470	V	97.3	Very high	96.7	Very high	28 Å²	28	33.9 Å²	33.9	17%	0.17	19%	0.188	C	C	.	.	H	α-helix	trans	-62.4	-40.1	177	173	0	0	0	0	110.9	A282 F285 L466 L473 G474	A282-V470 HydrophobicContact CB-CG1 3.85Å; F285-V470 HydrophobicContact CB-CG1 4.02Å; F285-V470 HydrophobicContact CD1-CB 4.02Å; F285-V470 HydrophobicContact CD1-CG1 3.76Å; F285-V470 HydrophobicContact CD1-CG2 4.17Å; F285-V470 HydrophobicContact CE1-CB 4.26Å; F285-V470 HydrophobicContact CE1-CG1 4.41Å; F285-V470 HydrophobicContact CE1-CG2 3.98Å; F285-V470 HydrophobicContact CG-CG1 3.84Å; F285-V470 HydrophobicContact CZ-CG2 4.3Å; L466-V470 HydrophobicContact CD1-CG2 4.07Å; L466-V470 HydrophobicContact CG-CG2 4.14Å; L466-V470 WeakPolarHBondContact O-CG2 3.33Å; L466-V470 PolarHBondContact O-N 2.83Å; V470-L473 PolarHBondContact O-N 3.31Å; V470-G474 PolarHBondContact O-N 3.23Å
471	G	96.3	Very high	96.7	Very high	0 Å²	0	33.9 Å²	33.9	0%	0	19%	0.188	C	C	.	.	H	α-helix	trans	-58.1	-47.9	172.3	0	0	0	0	0	111.9	L363 C467 F469 L473 G474 G475	L363-G471 VanDerWaalsContact CG-O 3.29Å; L363-G471 WeakPolarHBondContact CG-O 3.47Å; C467-G471 PolarHBondContact O-N 2.96Å; F469-G471 VanDerWaalsContact C-N 3.31Å; F469-G471 PolarHBondContact O-N 3.44Å; G471-L473 VanDerWaalsContact C-N 3.33Å; G471-L473 PolarHBondContact O-N 2.8Å; G471-G474 PolarHBondContact O-N 3.31Å; G471-G475 PolarHBondContact O-N 3.44Å
472	A	96.1	Very high	96.6	Very high	37 Å²	37	33 Å²	33	31%	0.306	18%	0.184	S	C	.	.	H	α-helix	trans	-59	-42.7	177	0	0	0	0	0	112.7	L364 A367 A468 F469 G475 A476	L364-A472 VanDerWaalsContact CD2-O 3.32Å; L364-A472 WeakPolarHBondContact CD2-O 3.39Å; A367-A472 HydrophobicContact CB-CB 4.47Å; A468-A472 PolarHBondContact O-N 3.06Å; F469-A472 WeakPolarHBondContact O-CB 3.48Å; F469-A472 PolarHBondContact O-N 3Å; A472-G475 PolarHBondContact O-N 2.92Å; A472-A476 PolarHBondContact O-N 2.64Å
473	L	97.1	Very high	96.6	Very high	96 Å²	96	33.9 Å²	33.9	50%	0.503	19%	0.191	S	C	.	.	H	α-helix	trans	-63.4	-43.3	175.6	-69.2	-179.3	0	0	0	112.5	F469 V470 G471 G475 A476 A477	F469-L473 HydrophobicContact CD1-CD1 4.03Å; F469-L473 HydrophobicContact CE1-CD1 3.44Å; F469-L473 VanDerWaalsContact CE1-CD1 3.44Å; F469-L473 HydrophobicContact CE1-CG 4.16Å; F469-L473 HydrophobicContact CZ-CD1 3.78Å; F469-L473 HydrophobicContact CZ-CD2 4.36Å; F469-L473 HydrophobicContact CZ-CG 4.17Å; F469-L473 PolarHBondContact O-N 3.38Å; V470-L473 PolarHBondContact O-N 3.31Å; G471-L473 VanDerWaalsContact C-N 3.33Å; G471-L473 PolarHBondContact O-N 2.8Å; L473-G475 VanDerWaalsContact C-N 3.31Å; L473-G475 PolarHBondContact O-N 3.09Å; L473-A476 WeakPolarHBondContact O-CB 3.35Å; L473-A476 PolarHBondContact O-N 3.44Å; L473-A477 PolarHBondContact O-N 3.34Å
474	G	97.2	Very high	96.4	Very high	3 Å²	3	37.8 Å²	37.8	3%	0.031	21%	0.208	C	C	.	.	H	α-helix	trans	-64.3	-37.6	175.9	0	0	0	0	0	112.7	V470 G471 A476 A477 F478	V470-G474 PolarHBondContact O-N 3.23Å; G471-G474 PolarHBondContact O-N 3.31Å; G474-A476 VanDerWaalsContact C-N 3.34Å; G474-A477 WeakPolarHBondContact O-CB 3.46Å; G474-A477 PolarHBondContact O-N 3.02Å; G474-A477 VanDerWaalsContact O-N 3.15Å; G474-F478 WeakPolarHBondContact O-CD2 3.34Å; G474-F478 PolarHBondContact O-N 2.85Å
475	G	97.3	Very high	96.3	Very high	0 Å²	0	37.8 Å²	37.8	0%	0	21%	0.208	C	C	.	.	H	α-helix	trans	-64	-39.9	174.5	0	0	0	0	0	112.3	L363 G471 A472 L473 A477 F478 L479	L363-G475 VanDerWaalsContact CD2-N 3.34Å; G471-G475 PolarHBondContact O-N 3.44Å; A472-G475 PolarHBondContact O-N 2.92Å; L473-G475 VanDerWaalsContact C-N 3.31Å; L473-G475 PolarHBondContact O-N 3.09Å; G475-A477 VanDerWaalsContact C-N 3.33Å; G475-A477 PolarHBondContact O-N 3.17Å; G475-F478 PolarHBondContact O-N 2.02Å; G475-L479 PolarHBondContact O-N 3Å
476	A	97.4	Very high	96.2	Very high	52 Å²	52	37.4 Å²	37.4	43%	0.43	21%	0.206	S	C	.	.	H	α-helix	trans	-63.8	-36.4	171.2	0	0	0	0	0	112.4	A472 L473 G474 F478 L479 G480	A472-A476 PolarHBondContact O-N 2.64Å; L473-A476 WeakPolarHBondContact O-CB 3.35Å; L473-A476 PolarHBondContact O-N 3.44Å; G474-A476 VanDerWaalsContact C-N 3.34Å; A476-F478 VanDerWaalsContact C-N 3.35Å; A476-L479 WeakPolarHBondContact O-CB 3.36Å; A476-L479 PolarHBondContact O-N 3.22Å; A476-G480 PolarHBondContact O-N 3.16Å
477	A	97.9	Very high	95.9	Very high	14 Å²	14	38.8 Å²	38.8	12%	0.116	21%	0.213	C	C	.	.	H	α-helix	trans	-64.2	-38.1	173.5	0	0	0	0	0	112	L278 L473 G474 G475 G480 T481	L278-A477 HydrophobicContact CB-CB 4.31Å; L473-A477 PolarHBondContact O-N 3.34Å; G474-A477 WeakPolarHBondContact O-CB 3.46Å; G474-A477 PolarHBondContact O-N 3.02Å; G474-A477 VanDerWaalsContact O-N 3.15Å; G475-A477 VanDerWaalsContact C-N 3.33Å; G475-A477 PolarHBondContact O-N 3.17Å; A477-G480 CarbonylContact O-C 3.57Å; A477-G480 PolarHBondContact O-N 3.49Å; A477-T481 PolarHBondContact O-N 3.44Å; A477-T481 PolarHBondContact O-OG1 3.25Å
478	F	98	Very high	95.7	Very high	0 Å²	0	38.8 Å²	38.8	0%	0	21%	0.213	C	C	.	.	H	α-helix	trans	-67	-37.9	172.2	-74	-51.1	0	0	0	113.1	F280 V283 C359 A360 L363 V402 G474 G475 A476 G480 T481 A482	F280-F478 HydrophobicContact CB-CZ 4.48Å; V283-F478 HydrophobicContact CG2-CE2 4.12Å; C359-F478 HydrophobicContact CB-CB 4.15Å; C359-F478 HydrophobicContact CB-CD1 3.72Å; C359-F478 HydrophobicContact CB-CD2 3.67Å; C359-F478 HydrophobicContact CB-CE1 3.96Å; C359-F478 HydrophobicContact CB-CE2 3.88Å; C359-F478 HydrophobicContact CB-CG 3.59Å; C359-F478 HydrophobicContact CB-CZ 4.03Å; A360-F478 HydrophobicContact CB-CB 3.73Å; L363-F478 HydrophobicContact CB-CD2 4.38Å; L363-F478 HydrophobicContact CD2-CD2 4.04Å; L363-F478 HydrophobicContact CD2-CE2 3.87Å; V402-F478 HydrophobicContact CG2-CE1 3.71Å; V402-F478 HydrophobicContact CG2-CZ 3.58Å; G474-F478 WeakPolarHBondContact O-CD2 3.34Å; G474-F478 PolarHBondContact O-N 2.85Å; G475-F478 PolarHBondContact O-N 2.02Å; A476-F478 VanDerWaalsContact C-N 3.35Å; F478-G480 VanDerWaalsContact C-N 3.29Å; F478-G480 PolarHBondContact O-N 3.45Å; F478-T481 VanDerWaalsContact O-CB 3.28Å; F478-T481 WeakPolarHBondContact O-CB 3.32Å; F478-T481 PolarHBondContact O-N 3Å; F478-A482 PolarHBondContact O-N 2.73Å
479	L	97.3	Very high	95.5	Very high	79 Å²	79	42.2 Å²	42.2	41%	0.414	22%	0.223	S	C	.	.	H	α-helix	trans	-60.4	-42.2	169.7	-70.9	179	0	0	0	111.4	L357 A360 L364 G475 A476 T481 A482 M483	L357-L479 HydrophobicContact CD2-CD2 4.09Å; A360-L479 HydrophobicContact CB-CD2 3.55Å; A360-L479 HydrophobicContact CB-CG 3.71Å; L364-L479 HydrophobicContact CD1-CD1 3.69Å; L364-L479 HydrophobicContact CD1-CG 4.18Å; G475-L479 PolarHBondContact O-N 3Å; A476-L479 WeakPolarHBondContact O-CB 3.36Å; A476-L479 PolarHBondContact O-N 3.22Å; L479-T481 VanDerWaalsContact C-N 3.32Å; L479-T481 PolarHBondContact O-N 3.25Å; L479-A482 WeakPolarHBondContact O-CB 3.32Å; L479-A482 PolarHBondContact O-N 3.34Å; L479-A482 VanDerWaalsContact O-N 3.17Å; L479-M483 PolarHBondContact O-N 2.58Å
480	G	96.8	Very high	95.1	Very high	9 Å²	9	42 Å²	42	9%	0.093	22%	0.218	C	C	.	.	H	α-helix	trans	-58	-44.6	172.9	0	0	0	0	0	112.2	A476 A477 F478 A482 M483 F484	A476-G480 PolarHBondContact O-N 3.16Å; A477-G480 CarbonylContact O-C 3.57Å; A477-G480 PolarHBondContact O-N 3.49Å; F478-G480 VanDerWaalsContact C-N 3.29Å; F478-G480 PolarHBondContact O-N 3.45Å; G480-A482 VanDerWaalsContact C-N 3.27Å; G480-A482 PolarHBondContact O-N 3.45Å; G480-M483 WeakPolarHBondContact O-CB 3.37Å; G480-M483 PolarHBondContact O-N 2.92Å; G480-F484 VanDerWaalsContact O-CD2 3.24Å; G480-F484 WeakPolarHBondContact O-CD2 3.36Å
481	T	96.4	Very high	94.6	Very high	0 Å²	0	44.9 Å²	44.9	0%	0	23%	0.226	C	C	.	.	H	α-helix	trans	-55.8	-43.7	175.3	-53.9	0	0	0	0	110.8	L275 S276 P356 I405 A477 F478 L479 M483 F484 I485	L275-T481 VanDerWaalsContact CB-OG1 3.23Å; L275-T481 WeakPolarHBondContact CB-OG1 3.43Å; S276-T481 PolarHBondContact N-OG1 2.84Å; S276-T481 VanDerWaalsContact N-OG1 3.13Å; P356-T481 HydrophobicContact CB-CG2 3.83Å; P356-T481 HydrophobicContact CG-CG2 4.43Å; I405-T481 HydrophobicContact CG2-CG2 4.48Å; A477-T481 PolarHBondContact O-N 3.44Å; A477-T481 PolarHBondContact O-OG1 3.25Å; F478-T481 VanDerWaalsContact O-CB 3.28Å; F478-T481 WeakPolarHBondContact O-CB 3.32Å; F478-T481 PolarHBondContact O-N 3Å; L479-T481 VanDerWaalsContact C-N 3.32Å; L479-T481 PolarHBondContact O-N 3.25Å; T481-M483 PolarHBondContact O-N 3.4Å; T481-M483 VanDerWaalsContact O-N 3.14Å; T481-F484 PolarHBondContact O-N 3.01Å; T481-F484 VanDerWaalsContact O-N 3.11Å; T481-I485 HydrophobicContact CG2-CD1 3.95Å; T481-I485 WeakPolarHBondContact O-CB 3.38Å; T481-I485 PolarHBondContact O-N 3.14Å
482	A	96.1	Very high	93.9	Very high	5 Å²	5	45.2 Å²	45.2	4%	0.041	23%	0.229	C	C	.	.	H	α-helix	trans	-60.4	-24.2	178.9	0	0	0	0	0	113.8	R353 P356 L357 F478 L479 G480	R353-A482 HydrophobicContact CB-CB 4.49Å; R353-A482 VanDerWaalsContact CD-O 3.29Å; R353-A482 WeakPolarHBondContact CD-O 3.3Å; P356-A482 HydrophobicContact CB-CB 4.01Å; P356-A482 HydrophobicContact CG-CB 3.81Å; L357-A482 HydrophobicContact CD2-CB 3.76Å; L357-A482 HydrophobicContact CG-CB 3.95Å; F478-A482 PolarHBondContact O-N 2.73Å; L479-A482 WeakPolarHBondContact O-CB 3.32Å; L479-A482 PolarHBondContact O-N 3.34Å; L479-A482 VanDerWaalsContact O-N 3.17Å; G480-A482 VanDerWaalsContact C-N 3.27Å; G480-A482 PolarHBondContact O-N 3.45Å
483	M	95.4	Very high	93.3	Very high	120 Å²	120	47.8 Å²	47.8	59%	0.591	24%	0.235	S	C	*	.	H	α-helix	trans	-74.2	-32.5	176.8	-60	-167.8	-74.1	0	0	113	L479 G480 T481	L479-M483 PolarHBondContact O-N 2.58Å; G480-M483 WeakPolarHBondContact O-CB 3.37Å; G480-M483 PolarHBondContact O-N 2.92Å; T481-M483 PolarHBondContact O-N 3.4Å; T481-M483 VanDerWaalsContact O-N 3.14Å
484	F	93.9	Very high	92.5	Very high	83 Å²	83	44.8 Å²	44.8	36%	0.364	22%	0.219	S	C	.	.	H	α-helix	trans	-105.5	-11.1	-174	-59.4	-76.9	0	0	0	114	P271 S272 L275 G480 T481 E486 D487 D488	P271-F484 HydrophobicContact CB-CB 4.23Å; P271-F484 HydrophobicContact CB-CD1 4.37Å; P271-F484 HydrophobicContact CB-CD2 4.07Å; P271-F484 HydrophobicContact CB-CG 3.96Å; P271-F484 HydrophobicContact CG-CB 3.8Å; P271-F484 HydrophobicContact CG-CD1 4Å; P271-F484 HydrophobicContact CG-CD2 4.43Å; P271-F484 HydrophobicContact CG-CG 3.82Å; S272-F484 VanDerWaalsContact OG-C 3.28Å; S272-F484 PolarHBondContact OG-O 3.22Å; L275-F484 HydrophobicContact CD1-CD2 3.91Å; L275-F484 HydrophobicContact CD1-CE2 4.09Å; G480-F484 VanDerWaalsContact O-CD2 3.24Å; G480-F484 WeakPolarHBondContact O-CD2 3.36Å; T481-F484 PolarHBondContact O-N 3.01Å; T481-F484 VanDerWaalsContact O-N 3.11Å; F484-E486 VanDerWaalsContact C-N 3.31Å; F484-E486 PolarHBondContact O-N 2.85Å; F484-D487 PolarHBondContact O-N 3.41Å; F484-D488 PolarHBondContact O-N 3.22Å
485	I	94.1	Very high	91.6	Very high	2 Å²	2	47.3 Å²	47.3	1%	0.01	23%	0.23	C	C	.	.	H	α-helix	trans	-59.8	-36.8	-169.8	-162.7	77.6	0	0	0	113.8	S272 R353 P356 I405 Y408 V409 T481 R489	S272-I485 VanDerWaalsContact OG-CA 3.29Å; S272-I485 WeakPolarHBondContact OG-CA 3.3Å; S272-I485 PolarHBondContact OG-N 3.15Å; R353-I485 HydrophobicContact CB-CG2 4.1Å; R353-I485 HydrophobicContact CG-CG2 3.87Å; P356-I485 HydrophobicContact CG-CB 4.21Å; P356-I485 HydrophobicContact CG-CD1 4.47Å; P356-I485 HydrophobicContact CG-CG1 4.18Å; P356-I485 HydrophobicContact CG-CG2 4.08Å; I405-I485 HydrophobicContact CG2-CD1 3.88Å; Y408-I485 HydrophobicContact CE2-CD1 3.66Å; Y408-I485 HydrophobicContact CE2-CG1 3.69Å; V409-I485 HydrophobicContact CG1-CD1 3.42Å; V409-I485 VanDerWaalsContact CG1-CD1 3.42Å; V409-I485 HydrophobicContact CG1-CG1 4.34Å; T481-I485 HydrophobicContact CG2-CD1 3.95Å; T481-I485 WeakPolarHBondContact O-CB 3.38Å; T481-I485 PolarHBondContact O-N 3.14Å; I485-R489 WeakPolarHBondContact O-CB 3.38Å; I485-R489 PolarHBondContact O-N 3.2Å
486	E	93.1	Very high	90.4	Very high	67 Å²	67	52.7 Å²	52.7	31%	0.313	26%	0.256	S	S	.	.	H	α-helix	trans	-67.9	-46.5	-179.7	-75.1	175.3	-168.6	0	0	111.4	P352 R353 F484 R489 R490	P352-E486 HydrophobicContact CB-CG 4.49Å; P352-E486 HydrophobicContact CG-CG 4.26Å; P352-E486 VanDerWaalsContact CG-OE1 3.24Å; P352-E486 WeakPolarHBondContact CG-OE1 3.23Å; R353-E486 HydrophobicContact CG-CG 4.07Å; R353-E486 WeakPolarHBondContact CG-OE1 3.26Å; R353-E486 IonicContact CZ-OE1 2.7Å; R353-E486 IonicContact CZ-OE2 3.93Å; R353-E486 IonicContact NE-OE1 3.66Å; R353-E486 PolarHBondContact NE-OE1 2.91Å; R353-E486 IonicContact NE-OE2 3.9Å; R353-E486 IonicContact NH2-OE1 2.91Å; R353-E486 PolarHBondContact NH2-OE1 3.32Å; R353-E486 IonicContact NH2-OE2 2.72Å; R353-E486 PolarHBondContact NH2-OE2 2.94Å; F484-E486 VanDerWaalsContact C-N 3.31Å; F484-E486 PolarHBondContact O-N 2.85Å; E486-R489 PolarHBondContact O-N 2.95Å; E486-R490 WeakPolarHBondContact O-CB 3.34Å; E486-R490 PolarHBondContact O-N 3.03Å
487	D	90.8	Very high	89.4	Confident	75 Å²	75	56.6 Å²	56.6	40%	0.401	27%	0.266	S	S	.	.	H	α-helix	trans	-65.8	-45	179.8	-68	-30.3	0	0	0	110.9	F484 R490 R491	F484-D487 PolarHBondContact O-N 3.41Å; D487-R490 PolarHBondContact O-N 2.95Å; D487-R491 WeakPolarHBondContact O-CB 3.34Å; D487-R491 VanDerWaalsContact O-CG 3.3Å; D487-R491 WeakPolarHBondContact O-CG 3.45Å; D487-R491 PolarHBondContact O-N 3Å
488	D	91.2	Very high	88.2	Confident	3 Å²	3	58 Å²	58	2%	0.016	28%	0.281	C	S	.	.	H	α-helix	trans	-64.5	-41.8	178.7	-70.8	-25.2	0	0	0	112.2	N270 P271 S272 V409 F484 R491 A492	N270-D488 PolarHBondContact OD1-OD2 3.48Å; P271-D488 WeakPolarHBondContact CD-OD2 3.49Å; P271-D488 WeakPolarHBondContact CG-OD2 3.42Å; S272-D488 WeakPolarHBondContact CB-OD2 3.29Å; S272-D488 PolarHBondContact N-OD2 3.18Å; S272-D488 PolarHBondContact OG-OD2 3.34Å; V409-D488 HydrophobicContact CB-CB 4.33Å; V409-D488 HydrophobicContact CG1-CB 4.32Å; F484-D488 PolarHBondContact O-N 3.22Å; D488-R491 PolarHBondContact O-N 3.07Å; D488-R491 IonicContact OD1-CZ 3.63Å; D488-R491 VanDerWaalsContact OD1-CZ 3.31Å; D488-R491 IonicContact OD1-NE 2.71Å; D488-R491 PolarHBondContact OD1-NE 3.48Å; D488-R491 IonicContact OD1-NH2 2.8Å; D488-R491 PolarHBondContact OD1-NH2 2.9Å; D488-A492 WeakPolarHBondContact O-CB 3.12Å; D488-A492 PolarHBondContact O-N 3.32Å
489	R	89.6	Confident	86.9	Confident	85 Å²	85	60.7 Å²	60.7	32%	0.321	30%	0.295	S	S	.	.	H	α-helix	trans	-62.5	-44.2	174.1	-176.3	177.6	-172	170.1	4.9	111.4	Y408 I485 E486 A492 Q493	Y408-R489 HydrophobicContact CD2-CB 4.12Å; Y408-R489 HydrophobicContact CD2-CG 3.88Å; I485-R489 WeakPolarHBondContact O-CB 3.38Å; I485-R489 PolarHBondContact O-N 3.2Å; E486-R489 PolarHBondContact O-N 2.95Å; R489-A492 PolarHBondContact O-N 3.08Å; R489-Q493 WeakPolarHBondContact O-CB 3.31Å; R489-Q493 VanDerWaalsContact O-CG 3.29Å; R489-Q493 WeakPolarHBondContact O-CG 3.39Å; R489-Q493 PolarHBondContact O-N 2.72Å
490	R	88.2	Confident	85.4	Confident	124 Å²	124	57.3 Å²	57.3	47%	0.468	28%	0.277	S	S	.	.	H	α-helix	trans	-63.8	-43	177.8	-172.3	179.2	-178.7	-172.4	-0.4	111.2	E486 D487 Q493 L494	E486-R490 WeakPolarHBondContact O-CB 3.34Å; E486-R490 PolarHBondContact O-N 3.03Å; D487-R490 PolarHBondContact O-N 2.95Å; R490-Q493 PolarHBondContact O-N 3.16Å; R490-L494 HydrophobicContact CG-CD1 4.16Å; R490-L494 WeakPolarHBondContact O-CB 3.36Å; R490-L494 VanDerWaalsContact O-CG 3.32Å; R490-L494 WeakPolarHBondContact O-CG 3.28Å; R490-L494 PolarHBondContact O-N 2.9Å
491	R	85.8	Confident	83.7	Confident	88 Å²	88	61.8 Å²	61.8	33%	0.332	30%	0.296	S	S	.	.	H	α-helix	trans	-59.1	-47	174.9	-75.2	-167	-72.4	178.1	-9.2	111.6	D487 D488 Q493 L494 H495	D487-R491 WeakPolarHBondContact O-CB 3.34Å; D487-R491 VanDerWaalsContact O-CG 3.3Å; D487-R491 WeakPolarHBondContact O-CG 3.45Å; D487-R491 PolarHBondContact O-N 3Å; D488-R491 PolarHBondContact O-N 3.07Å; D488-R491 IonicContact OD1-CZ 3.63Å; D488-R491 VanDerWaalsContact OD1-CZ 3.31Å; D488-R491 IonicContact OD1-NE 2.71Å; D488-R491 PolarHBondContact OD1-NE 3.48Å; D488-R491 IonicContact OD1-NH2 2.8Å; D488-R491 PolarHBondContact OD1-NH2 2.9Å; R491-Q493 PolarHBondContact O-N 3.37Å; R491-L494 PolarHBondContact O-N 3.41Å; R491-H495 WeakPolarHBondContact O-CB 3.26Å; R491-H495 PolarHBondContact O-N 3.42Å
492	A	82.3	Confident	81.9	Confident	7 Å²	7	66.4 Å²	66.4	6%	0.058	32%	0.318	C	S	.	.	H	α-helix	trans	-60.8	-43.9	176.8	0	0	0	0	0	112	I411 D488 R489 H495 M496	I411-A492 HydrophobicContact CG2-CB 4.25Å; D488-A492 WeakPolarHBondContact O-CB 3.12Å; D488-A492 PolarHBondContact O-N 3.32Å; R489-A492 PolarHBondContact O-N 3.08Å; A492-H495 PolarHBondContact O-N 2.86Å; A492-M496 WeakPolarHBondContact O-CG 3.43Å; A492-M496 PolarHBondContact O-N 2.75Å
493	Q	83.4	Confident	79.5	Confident	92 Å²	92	69 Å²	69	43%	0.43	33%	0.333	S	S	.	.	H	α-helix	trans	-62.6	-44.6	177.2	-74.6	173.1	-20.2	0	0	112.8	R489 R490 R491 H495 M496 Q497	R489-Q493 WeakPolarHBondContact O-CB 3.31Å; R489-Q493 VanDerWaalsContact O-CG 3.29Å; R489-Q493 WeakPolarHBondContact O-CG 3.39Å; R489-Q493 PolarHBondContact O-N 2.72Å; R490-Q493 PolarHBondContact O-N 3.16Å; R491-Q493 PolarHBondContact O-N 3.37Å; Q493-H495 VanDerWaalsContact C-N 3.3Å; Q493-H495 PolarHBondContact O-N 3.29Å; Q493-M496 WeakPolarHBondContact O-CB 3.49Å; Q493-M496 PolarHBondContact O-N 3.5Å; Q493-Q497 WeakPolarHBondContact O-CG 3.22Å; Q493-Q497 PolarHBondContact O-N 3.29Å
494	L	81.4	Confident	77.2	Confident	32 Å²	32	65.9 Å²	65.9	17%	0.168	33%	0.331	C	S	.	.	H	α-helix	trans	-64.8	-35.3	177.7	-72.6	171.8	0	0	0	112.1	R490 R491 Q497 G498 L499 L500	R490-L494 HydrophobicContact CG-CD1 4.16Å; R490-L494 WeakPolarHBondContact O-CB 3.36Å; R490-L494 VanDerWaalsContact O-CG 3.32Å; R490-L494 WeakPolarHBondContact O-CG 3.28Å; R490-L494 PolarHBondContact O-N 2.9Å; R491-L494 PolarHBondContact O-N 3.41Å; L494-Q497 PolarHBondContact O-N 3.38Å; L494-G498 PolarHBondContact O-N 3.4Å; L494-L499 HydrophobicContact CD2-CB 4.32Å; L494-L499 HydrophobicContact CD2-CD1 3.9Å; L494-L499 PolarHBondContact O-N 3.47Å; L494-L500 HydrophobicContact CB-CB 4.44Å; L494-L500 HydrophobicContact CB-CD1 3.37Å; L494-L500 HydrophobicContact CB-CG 4.17Å; L494-L500 HydrophobicContact CD1-CD1 3.82Å; L494-L500 HydrophobicContact CG-CD1 4.24Å; L494-L500 PolarHBondContact O-N 3.33Å
495	H	77.3	Confident	74.7	Confident	56 Å²	56	66.4 Å²	66.4	26%	0.259	34%	0.343	S	S	.	.	H	α-helix	trans	-65.6	-42.8	173.9	-143.5	83.5	0	0	0	111.4	I411 R491 A492 Q493 Q497 G498 L500	I411-H495 HydrophobicContact CG2-CB 3.88Å; R491-H495 WeakPolarHBondContact O-CB 3.26Å; R491-H495 PolarHBondContact O-N 3.42Å; A492-H495 PolarHBondContact O-N 2.86Å; Q493-H495 VanDerWaalsContact C-N 3.3Å; Q493-H495 PolarHBondContact O-N 3.29Å; H495-Q497 VanDerWaalsContact C-N 3.26Å; H495-Q497 PolarHBondContact O-N 3Å; H495-G498 PolarHBondContact O-N 3.46Å; H495-L500 HydrophobicContact CB-CB 4.47Å; H495-L500 PolarHBondContact CE1-O 3.03Å; H495-L500 PolarHBondContact ND1-O 3.17Å
496	M	72.9	Confident	72.5	Confident	114 Å²	114	71.6 Å²	71.6	56%	0.562	38%	0.38	S	S	*	.	H	α-helix	trans	-63.9	-30	175	-70.7	176.9	63.2	0	0	113	P412 A492 Q493 G498	P412-M496 HydrophobicContact CG-CE 4.09Å; P412-M496 HydrophobicContact CG-CG 4.34Å; P412-M496 HydrophobicContact CG-SD 4.12Å; A492-M496 WeakPolarHBondContact O-CG 3.43Å; A492-M496 PolarHBondContact O-N 2.75Å; Q493-M496 WeakPolarHBondContact O-CB 3.49Å; Q493-M496 PolarHBondContact O-N 3.5Å; M496-G498 PolarHBondContact O-N 2.87Å
497	Q	76.3	Confident	70.5	Confident	134 Å²	134	70.7 Å²	70.7	63%	0.626	38%	0.377	S	S	*	.	T	Hydrogen-bonded Turn	trans	-80.5	-1	174.6	-69.9	173.3	-4.4	0	0	113.3	Q493 L494 H495 L499	Q493-Q497 WeakPolarHBondContact O-CG 3.22Å; Q493-Q497 PolarHBondContact O-N 3.29Å; L494-Q497 PolarHBondContact O-N 3.38Å; H495-Q497 VanDerWaalsContact C-N 3.26Å; H495-Q497 PolarHBondContact O-N 3Å; Q497-L499 HydrophobicContact CB-CD1 4.01Å; Q497-L499 HydrophobicContact CB-CG 4.12Å; Q497-L499 PolarHBondContact O-N 2.74Å
498	G	71.5	Confident	68.9	Low	42 Å²	42	70.1 Å²	70.1	43%	0.433	37%	0.374	S	S	.	.	T	Hydrogen-bonded Turn	trans	71.1	10.7	-177.5	0	0	0	0	0	114.4	L494 H495 M496	L494-G498 PolarHBondContact O-N 3.4Å; H495-G498 PolarHBondContact O-N 3.46Å; M496-G498 PolarHBondContact O-N 2.87Å
499	L	70.8	Confident	67.2	Low	58 Å²	58	74.6 Å²	74.6	30%	0.304	39%	0.391	S	S	.	.			trans	-85	-14.1	-177.7	-67.9	171.4	0	0	0	113.1	L494 Q497 I510 V511	L494-L499 HydrophobicContact CD2-CB 4.32Å; L494-L499 HydrophobicContact CD2-CD1 3.9Å; L494-L499 PolarHBondContact O-N 3.47Å; Q497-L499 HydrophobicContact CB-CD1 4.01Å; Q497-L499 HydrophobicContact CB-CG 4.12Å; Q497-L499 PolarHBondContact O-N 2.74Å; L499-I510 WeakPolarHBondContact O-CA 3.18Å; L499-V511 PolarHBondContact O-N 3.39Å
500	L	65.4	Low	65.6	Low	7 Å²	7	71.5 Å²	71.5	4%	0.037	38%	0.38	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-118.2	128.8	176.8	-98.4	158.9	0	0	0	109.5	L494 H495 D508 I510 V523	L494-L500 HydrophobicContact CB-CB 4.44Å; L494-L500 HydrophobicContact CB-CD1 3.37Å; L494-L500 HydrophobicContact CB-CG 4.17Å; L494-L500 HydrophobicContact CD1-CD1 3.82Å; L494-L500 HydrophobicContact CG-CD1 4.24Å; L494-L500 PolarHBondContact O-N 3.33Å; H495-L500 HydrophobicContact CB-CB 4.47Å; H495-L500 PolarHBondContact CE1-O 3.03Å; H495-L500 PolarHBondContact ND1-O 3.17Å; L500-D508 HydrophobicContact CD2-CB 4.01Å; L500-I510 HydrophobicContact CD2-CG1 4.14Å; L500-I510 HydrophobicContact CG-CG1 4.19Å; L500-V523 HydrophobicContact CD2-CG2 3.74Å
501	H	61.9	Low	64.4	Low	104 Å²	104	67.4 Å²	67.4	48%	0.481	37%	0.369	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-120.4	128.5	172	-82.3	2.8	0	0	0	109.7	T503	H501-T503 PolarHBondContact O-N 3.46Å
502	E	58.2	Low	63.4	Low	97 Å²	97	65.7 Å²	65.7	45%	0.453	37%	0.368	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-72.8	92.3	172.4	-83.3	179.6	-179.6	0	0	109.2	R414	R414-E502 IonicContact CZ-OE1 3.62Å; R414-E502 IonicContact CZ-OE2 3.71Å; R414-E502 IonicContact NH1-OE1 3.76Å; R414-E502 PolarHBondContact NH1-OE1 2.86Å; R414-E502 IonicContact NH1-OE2 3.24Å; R414-E502 IonicContact NH2-OE1 2.71Å; R414-E502 PolarHBondContact NH2-OE1 3.47Å; R414-E502 IonicContact NH2-OE2 3.77Å; R414-E502 PolarHBondContact NH2-OE2 2.89Å
503	T	45.6	Very low	62	Low	58 Å²	58	70.8 Å²	70.8	36%	0.356	40%	0.4	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-96.3	90.3	171.2	40.5	0	0	0	0	110.6	H501 D507	H501-T503 PolarHBondContact O-N 3.46Å; T503-D507 PolarHBondContact OG1-O 3.22Å
504	G	48	Very low	60.3	Low	55 Å²	55	72.5 Å²	72.5	57%	0.567	41%	0.408	S	S	*	.	T	Hydrogen-bonded Turn	trans	63.2	-176.3	166.9	0	0	0	0	0	115.8	S506	G504-S506 PolarHBondContact O-N 3.23Å
505	P	41.7	Very low	58.6	Low	94 Å²	94	83.6 Å²	83.6	61%	0.61	45%	0.448	S	S	*	.	T	Hydrogen-bonded Turn	trans	-65.8	-7.3	-154	-21.9	32.4	0	0	0	118.3	R269	R269-P505 PolarHBondContact NH1-O 3Å; R269-P505 PolarHBondContact NH2-O 3.5Å; R269-P505 VanDerWaalsContact NH2-O 3.13Å
506	S	46.5	Very low	57.5	Low	111 Å²	111	84.9 Å²	84.9	78%	0.776	48%	0.477	S	S	*	.	T	Hydrogen-bonded Turn	trans	-153.1	11.2	-169.9	60.7	0	0	0	0	117.1	G504	G504-S506 PolarHBondContact O-N 3.23Å
507	D	52.2	Low	56.4	Low	48 Å²	48	89.6 Å²	89.6	26%	0.257	49%	0.488	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-139.3	81.6	-173.3	-137.7	10.7	0	0	0	112.5	T503 R509	T503-D507 PolarHBondContact OG1-O 3.22Å; D507-R509 PolarHBondContact O-N 3.16Å; D507-R509 IonicContact OD2-CZ 3.18Å; D507-R509 IonicContact OD2-NE 3.38Å; D507-R509 PolarHBondContact OD2-NE 3.48Å; D507-R509 IonicContact OD2-NH2 2.74Å; D507-R509 PolarHBondContact OD2-NH2 3.02Å
508	D	57.6	Low	55.3	Low	63 Å²	63	87.5 Å²	87.5	34%	0.337	49%	0.488	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-68.4	114.6	164.4	-70.5	-16.9	0	0	0	107.6	L500 V523	L500-D508 HydrophobicContact CD2-CB 4.01Å; D508-V523 HydrophobicContact CB-CB 4.39Å; D508-V523 HydrophobicContact CB-CG2 3.58Å; D508-V523 WeakPolarHBondContact O-CG2 3.48Å; D508-V523 PolarHBondContact O-N 3.01Å
509	R	56	Low	54.8	Low	98 Å²	98	88.1 Å²	88.1	37%	0.37	48%	0.483	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-114.4	127.7	-178.6	-68.9	-175.8	173.4	-163	-0.1	111	D507 R520 V521	D507-R509 PolarHBondContact O-N 3.16Å; D507-R509 IonicContact OD2-CZ 3.18Å; D507-R509 IonicContact OD2-NE 3.38Å; D507-R509 PolarHBondContact OD2-NE 3.48Å; D507-R509 IonicContact OD2-NH2 2.74Å; D507-R509 PolarHBondContact OD2-NH2 3.02Å; R509-R520 HydrophobicContact CB-CB 4.14Å; R509-V521 WeakPolarHBondContact CA-O 3.14Å
510	I	55.3	Low	54.3	Low	20 Å²	20	92.3 Å²	92.3	10%	0.103	50%	0.495	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-86.7	134	173.4	-59.2	172.2	0	0	0	108.6	L499 L500 V512 R520 V521 V523 V526	L499-I510 WeakPolarHBondContact O-CA 3.18Å; L500-I510 HydrophobicContact CD2-CG1 4.14Å; L500-I510 HydrophobicContact CG-CG1 4.19Å; I510-V512 HydrophobicContact CG2-CG2 4.18Å; I510-R520 WeakPolarHBondContact O-CA 3.41Å; I510-V521 PolarHBondContact N-O 3.31Å; I510-V521 PolarHBondContact O-N 3.17Å; I510-V523 HydrophobicContact CD1-CB 4.46Å; I510-V523 HydrophobicContact CD1-CG2 3.98Å; I510-V523 HydrophobicContact CG1-CG2 3.78Å; I510-V526 HydrophobicContact CD1-CB 4.02Å; I510-V526 HydrophobicContact CD1-CG1 4.26Å; I510-V526 HydrophobicContact CD1-CG2 4.1Å
511	V	62.3	Low	54.2	Low	38 Å²	38	94 Å²	94	23%	0.23	51%	0.506	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-87.7	111.7	171.6	-176.7	0	0	0	0	109.2	L499 R520	L499-V511 PolarHBondContact O-N 3.39Å; V511-R520 HydrophobicContact CG2-CG 4.37Å
512	V	65.1	Low	54	Low	51 Å²	51	91.2 Å²	91.2	31%	0.309	50%	0.497	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-101.5	125.1	177.1	-172.9	0	0	0	0	109.4	I510 Q514 T519 V521	I510-V512 HydrophobicContact CG2-CG2 4.18Å; V512-Q514 PolarHBondContact O-N 3.27Å; V512-Q514 VanDerWaalsContact O-N 3.08Å; V512-T519 PolarHBondContact N-O 3.15Å; V512-T519 PolarHBondContact O-N 3.24Å; V512-V521 HydrophobicContact CG2-CG2 4.25Å
513	P	52.6	Low	53.9	Low	114 Å²	114	87.7 Å²	87.7	74%	0.74	48%	0.482	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-75.4	95.6	172.4	28.2	-29.9	0	0	0	109.5
514	Q	48.8	Very low	54.4	Low	128 Å²	128	89 Å²	89	60%	0.598	49%	0.494	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-86.6	145.3	161.8	-83.6	-172.7	-22	0	0	109.4	V512 G516 R517	V512-Q514 PolarHBondContact O-N 3.27Å; V512-Q514 VanDerWaalsContact O-N 3.08Å; Q514-G516 PolarHBondContact O-N 2.99Å; Q514-R517 PolarHBondContact O-N 3.47Å
515	R	44.2	Very low	54.8	Low	266 Å²	266	89.8 Å²	89.8	100%	1.004	49%	0.49	S	S	*	.	T	Hydrogen-bonded Turn	trans	-41.9	100.4	179.6	-81.8	-178.2	171.9	178.4	-2.4	110.8
516	G	54.8	Low	55.5	Low	83 Å²	83	88.1 Å²	88.1	86%	0.856	48%	0.478	S	S	*	.	T	Hydrogen-bonded Turn	trans	98.1	-19.2	173.5	0	0	0	0	0	118	Q514	Q514-G516 PolarHBondContact O-N 2.99Å
517	R	50.5	Low	55.3	Low	213 Å²	213	86.7 Å²	86.7	80%	0.804	46%	0.461	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-149.2	134.1	176	-87.2	-175	174	171.5	-2.1	112.4	Q514 T519	Q514-R517 PolarHBondContact O-N 3.47Å; R517-T519 PolarHBondContact O-N 2.83Å
518	S	52.2	Low	54.7	Low	89 Å²	89	94.5 Å²	94.5	62%	0.622	50%	0.501	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-72.6	118.9	172.3	58.4	0	0	0	0	110.7
519	T	61.2	Low	54.5	Low	55 Å²	55	96.1 Å²	96.1	34%	0.337	51%	0.509	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-104.7	138.4	174.8	37.3	0	0	0	0	110.4	V512 R517	V512-T519 PolarHBondContact N-O 3.15Å; V512-T519 PolarHBondContact O-N 3.24Å; R517-T519 PolarHBondContact O-N 2.83Å
520	R	59.5	Low	54.4	Low	146 Å²	146	95.9 Å²	95.9	55%	0.551	52%	0.517	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-96.3	119.4	178.3	-68.8	-174.4	-174.6	178.9	2.4	109.3	R509 I510 V511	R509-R520 HydrophobicContact CB-CB 4.14Å; I510-R520 WeakPolarHBondContact O-CA 3.41Å; V511-R520 HydrophobicContact CG2-CG 4.37Å
521	V	64.5	Low	54.4	Low	42 Å²	42	100.2 Å²	100.2	26%	0.255	54%	0.54	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-121.2	141.9	-175	-170.3	0	0	0	0	109.8	R509 I510 V512 V526	R509-V521 WeakPolarHBondContact CA-O 3.14Å; I510-V521 PolarHBondContact N-O 3.31Å; I510-V521 PolarHBondContact O-N 3.17Å; V512-V521 HydrophobicContact CG2-CG2 4.25Å; V521-V526 HydrophobicContact CG1-CG2 4.21Å
522	P	57.5	Low	53.9	Low	46 Å²	46	103.8 Å²	103.8	30%	0.299	56%	0.558	S	S	.	*	E	Extended strand (participates in β ladder)	trans	-60.3	141.7	175.9	-19.1	30.4	0	0	0	111.8	S524 S525	P522-S524 PolarHBondContact O-N 2.88Å; P522-S525 WeakPolarHBondContact O-CB 3.43Å; P522-S525 PolarHBondContact O-N 3.29Å
523	V	55.7	Low	53.2	Low	23 Å²	23	107.1 Å²	107.1	14%	0.139	57%	0.573	C	S	.	*	G	3₁₀ helix	trans	-55.2	-36.7	178	169.8	0	0	0	0	112.5	L500 D508 I510 S525 V526 L527	L500-V523 HydrophobicContact CD2-CG2 3.74Å; D508-V523 HydrophobicContact CB-CB 4.39Å; D508-V523 HydrophobicContact CB-CG2 3.58Å; D508-V523 WeakPolarHBondContact O-CG2 3.48Å; D508-V523 PolarHBondContact O-N 3.01Å; I510-V523 HydrophobicContact CD1-CB 4.46Å; I510-V523 HydrophobicContact CD1-CG2 3.98Å; I510-V523 HydrophobicContact CG1-CG2 3.78Å; V523-S525 PolarHBondContact O-N 3.1Å; V523-V526 PolarHBondContact O-N 3.43Å; V523-L527 HydrophobicContact CG1-CD1 3.43Å; V523-L527 VanDerWaalsContact CG1-CD1 3.43Å; V523-L527 HydrophobicContact CG1-CG 4.18Å; V523-L527 PolarHBondContact O-N 3.27Å
524	S	56.2	Low	53.3	Low	87 Å²	87	106.7 Å²	106.7	61%	0.608	56%	0.562	S	S	*	*	G	3₁₀ helix	trans	-63.6	-21.8	179.2	54.6	0	0	0	0	114.1	P522	P522-S524 PolarHBondContact O-N 2.88Å
525	S	57	Low	53.6	Low	70 Å²	70	105.1 Å²	105.1	49%	0.49	56%	0.56	S	S	.	*	G	3₁₀ helix	trans	-85.7	-12.7	-179	-43.7	0	0	0	0	113.4	P522 V523	P522-S525 WeakPolarHBondContact O-CB 3.43Å; P522-S525 PolarHBondContact O-N 3.29Å; V523-S525 PolarHBondContact O-N 3.1Å
526	V	55.6	Low	54.3	Low	60 Å²	60	92.8 Å²	92.8	36%	0.364	53%	0.525	S	S	.	.	T	Hydrogen-bonded Turn	trans	-109.9	-15.2	-174.9	-174.2	0	0	0	0	112	I510 V521 V523	I510-V526 HydrophobicContact CD1-CB 4.02Å; I510-V526 HydrophobicContact CD1-CG1 4.26Å; I510-V526 HydrophobicContact CD1-CG2 4.1Å; V521-V526 HydrophobicContact CG1-CG2 4.21Å; V523-V526 PolarHBondContact O-N 3.43Å
527	L	42.1	Very low	54.3	Low	80 Å²	80	93.6 Å²	93.6	42%	0.419	50%	0.498	S	S	.	.			trans	-91.3	8.2	-179.8	-73	172.9	0	0	0	114.1	V523	V523-L527 HydrophobicContact CG1-CD1 3.43Å; V523-L527 VanDerWaalsContact CG1-CD1 3.43Å; V523-L527 HydrophobicContact CG1-CG 4.18Å; V523-L527 PolarHBondContact O-N 3.27Å
528	I	39.3	Very low	54.6	Low	212 Å²	212	82.7 Å²	82.7	100%	1.087	47%	0.47	S	S	*	.			trans	-89.5	0	174.8	-57.9	176.5	0	0	0	110.4

Retrieved 528 of 528 residues in 171.5 ms (Link to these results)

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