A0A061IBG7_CRIGR Loading...

Cytochrome P450 26A1

AlphaFold DB , UniProt , Accession A0A061IBG7, Species CRIGR (Cricetulus griseus, Chinese hamster), Gene LOC100755549, Length 499 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M55.3Low78Confident182 Ų18286.3 Ų86.390%0.89753%0.529SS*.  0122.20-76.9169.359.800108.1L6M1-L6 HydrophobicContact CE-CD2 4.12Å; M1-L6 HydrophobicContact CE-CG 4.47Å
2G75.9Confident78.6Confident47 Ų4786.1 Ų86.149%0.48553%0.532SS..  trans-64.4147.5-178.300000111.8P4 A5 L6G2-P4 WeakPolarHBondContact O-CD 3.4Å; G2-A5 WeakPolarHBondContact O-CB 3.47Å; G2-A5 PolarHBondContact O-N 2.83Å; G2-L6 PolarHBondContact O-N 3.49Å
3L75.3Confident79.3Confident130 Ų13085.3 Ų85.368%0.68153%0.527SS*.Hα-helixtrans-41.3-38172.9-161.477000114.1A5 L6 L7L3-A5 PolarHBondContact O-N 2.86Å; L3-L6 PolarHBondContact O-N 3.12Å; L3-L7 HydrophobicContact CG-CD1 4.2Å; L3-L7 WeakPolarHBondContact O-CB 3.23Å; L3-L7 WeakPolarHBondContact O-CG 3.03Å; L3-L7 PolarHBondContact O-N 3.48Å
4P80.8Confident80Confident98 Ų9889.9 Ų89.964%0.63654%0.536SS*.Hα-helixtrans-66.1-35.3177.4-20.133000114G2 L7 A8G2-P4 WeakPolarHBondContact O-CD 3.4Å; P4-L7 PolarHBondContact O-N 3.49Å; P4-A8 VanDerWaalsContact O-CB 3.29Å; P4-A8 WeakPolarHBondContact O-CB 3.31Å; P4-A8 PolarHBondContact O-N 2.69Å
5A79.5Confident80.7Confident50 Ų5088.2 Ų88.241%0.41353%0.527SS..Hα-helixtrans-72.9-36.3179.300000111.6G2 L3 S9G2-A5 WeakPolarHBondContact O-CB 3.47Å; G2-A5 PolarHBondContact O-N 2.83Å; L3-A5 PolarHBondContact O-N 2.86Å; A5-S9 VanDerWaalsContact O-CB 3.26Å; A5-S9 WeakPolarHBondContact O-CB 3.45Å; A5-S9 PolarHBondContact O-N 2.83Å
6L78.9Confident81.4Confident94 Ų9488.3 Ų88.349%0.49252%0.523SS..Hα-helixtrans-67.3-40.7172.9-74.7164.6000111.6M1 G2 L3 S9 A10M1-L6 HydrophobicContact CE-CD2 4.12Å; M1-L6 HydrophobicContact CE-CG 4.47Å; G2-L6 PolarHBondContact O-N 3.49Å; L3-L6 PolarHBondContact O-N 3.12Å; L6-S9 PolarHBondContact O-N 3.1Å; L6-A10 WeakPolarHBondContact O-CB 3.36Å; L6-A10 PolarHBondContact O-N 2.94Å
7L79.7Confident82.1Confident98 Ų9886.9 Ų86.951%0.51352%0.517SS..Hα-helixtrans-65.7-45.9174.9-78.5164.2000112.2L3 P4 S9 A10 L11L3-L7 HydrophobicContact CG-CD1 4.2Å; L3-L7 WeakPolarHBondContact O-CB 3.23Å; L3-L7 WeakPolarHBondContact O-CG 3.03Å; L3-L7 PolarHBondContact O-N 3.48Å; P4-L7 PolarHBondContact O-N 3.49Å; L7-S9 VanDerWaalsContact C-N 3.32Å; L7-S9 PolarHBondContact O-N 3.23Å; L7-A10 PolarHBondContact O-N 3.35Å; L7-L11 WeakPolarHBondContact O-CB 3.4Å; L7-L11 WeakPolarHBondContact O-CD1 3.43Å; L7-L11 PolarHBondContact O-N 2.95Å
8A82.8Confident82.6Confident51 Ų5187.7 Ų87.742%0.42152%0.518SS..Hα-helixtrans-62.1-41.3176.100000111.5P4 L11 C12P4-A8 VanDerWaalsContact O-CB 3.29Å; P4-A8 WeakPolarHBondContact O-CB 3.31Å; P4-A8 PolarHBondContact O-N 2.69Å; A8-L11 PolarHBondContact O-N 3.35Å; A8-C12 WeakPolarHBondContact O-CB 3.43Å; A8-C12 PolarHBondContact O-N 3.5Å; A8-C12 PolarHBondContact O-SG 3.35Å
9S82.9Confident83.1Confident62 Ų6288.4 Ų88.443%0.43452%0.518SS..Hα-helixtrans-62.5-48.3173.5-175.50000111.2A5 L6 L7 L11 C12 T13A5-S9 VanDerWaalsContact O-CB 3.26Å; A5-S9 WeakPolarHBondContact O-CB 3.45Å; A5-S9 PolarHBondContact O-N 2.83Å; L6-S9 PolarHBondContact O-N 3.1Å; L7-S9 VanDerWaalsContact C-N 3.32Å; L7-S9 PolarHBondContact O-N 3.23Å; S9-L11 VanDerWaalsContact C-N 3.34Å; S9-L11 PolarHBondContact O-N 3.26Å; S9-C12 PolarHBondContact O-N 3.32Å; S9-T13 VanDerWaalsContact O-CB 3.23Å; S9-T13 WeakPolarHBondContact O-CB 3.44Å; S9-T13 PolarHBondContact O-N 3.17Å; S9-T13 PolarHBondContact O-OG1 3.27Å
10A82.3Confident83.5Confident43 Ų4389.3 Ų89.336%0.35552%0.52SS..Hα-helixtrans-62.3-39.5178.400000112.8L6 L7 F14L6-A10 WeakPolarHBondContact O-CB 3.36Å; L6-A10 PolarHBondContact O-N 2.94Å; L7-A10 PolarHBondContact O-N 3.35Å; A10-F14 WeakPolarHBondContact O-CB 3.2Å; A10-F14 PolarHBondContact O-N 3.45Å
11L84.5Confident83.7Confident94 Ų9489.8 Ų89.849%0.49252%0.516SS..Iπ-helixtrans-61.7-48.8175.1-87.6154.7000111.7L7 A8 S9 V15 L16L7-L11 WeakPolarHBondContact O-CB 3.4Å; L7-L11 WeakPolarHBondContact O-CD1 3.43Å; L7-L11 PolarHBondContact O-N 2.95Å; A8-L11 PolarHBondContact O-N 3.35Å; S9-L11 VanDerWaalsContact C-N 3.34Å; S9-L11 PolarHBondContact O-N 3.26Å; L11-V15 HydrophobicContact CD2-CB 4.05Å; L11-V15 HydrophobicContact CD2-CG1 4.14Å; L11-V15 HydrophobicContact CD2-CG2 4.09Å; L11-V15 WeakPolarHBondContact O-CB 3.22Å; L11-V15 PolarHBondContact O-N 3.17Å; L11-V15 VanDerWaalsContact O-N 3.16Å; L11-L16 PolarHBondContact O-N 3.09Å
12C85.4Confident85.4Confident84 Ų8485.5 Ų85.557%0.56850%0.496SS*.Iπ-helixtrans-73-32.8-179.2-70.80000113.1A8 S9 P17A8-C12 WeakPolarHBondContact O-CB 3.43Å; A8-C12 PolarHBondContact O-N 3.5Å; A8-C12 PolarHBondContact O-SG 3.35Å; S9-C12 PolarHBondContact O-N 3.32Å; C12-P17 WeakPolarHBondContact O-CD 3.44Å
13T87.4Confident86.1Confident76 Ų7685.5 Ų85.547%0.46649%0.492SS..Iπ-helixtrans-85.4-32.3-175.7-51.70000113S9 P17S9-T13 VanDerWaalsContact O-CB 3.23Å; S9-T13 WeakPolarHBondContact O-CB 3.44Å; S9-T13 PolarHBondContact O-N 3.17Å; S9-T13 PolarHBondContact O-OG1 3.27Å; T13-P17 WeakPolarHBondContact O-CG 3.42Å
14F89.9Confident86.7Confident150 Ų15081.4 Ų81.466%0.65848%0.477SS*.Iπ-helixtrans-119.5-46.3-174.7-59.3-72.7000113.6A10 L18A10-F14 WeakPolarHBondContact O-CB 3.2Å; A10-F14 PolarHBondContact O-N 3.45Å; F14-L18 VanDerWaalsContact O-CB 3.29Å; F14-L18 WeakPolarHBondContact O-CB 3.33Å; F14-L18 PolarHBondContact O-N 3.17Å
15V90.6Very high87Confident64 Ų6478.5 Ų78.539%0.38846%0.457SS..Iπ-helixtrans-73.9-48.3-173.2-177.80000111.3L11 L18 L19L11-V15 HydrophobicContact CD2-CB 4.05Å; L11-V15 HydrophobicContact CD2-CG1 4.14Å; L11-V15 HydrophobicContact CD2-CG2 4.09Å; L11-V15 WeakPolarHBondContact O-CB 3.22Å; L11-V15 PolarHBondContact O-N 3.17Å; L11-V15 VanDerWaalsContact O-N 3.16Å; V15-L18 PolarHBondContact O-N 2.92Å; V15-L19 HydrophobicContact CG1-CD1 3.97Å; V15-L19 HydrophobicContact CG1-CG 4.33Å; V15-L19 WeakPolarHBondContact O-CG 3.5Å; V15-L19 PolarHBondContact O-N 3.43Å
16L91.9Very high87.4Confident90 Ų9082.1 Ų82.147%0.47146%0.464SS..Hα-helixtrans-62.8-46.9-178.9-17967.8000112.3L11 L18 L19 L20L11-L16 PolarHBondContact O-N 3.09Å; L16-L18 VanDerWaalsContact C-N 3.32Å; L16-L18 PolarHBondContact O-N 3.28Å; L16-L19 PolarHBondContact O-N 2.84Å; L16-L20 HydrophobicContact CD1-CD1 4.4Å; L16-L20 HydrophobicContact CD1-CG 4.31Å; L16-L20 HydrophobicContact CG-CD1 4.13Å; L16-L20 HydrophobicContact CG-CG 4.46Å; L16-L20 WeakPolarHBondContact O-CB 3.45Å; L16-L20 WeakPolarHBondContact O-CG 3.28Å; L16-L20 PolarHBondContact O-N 3.38Å
17P91.9Very high87.9Confident64 Ų6483.2 Ų83.242%0.41647%0.469SS..Hα-helixtrans-62-37.8175.5-26.638.2000113.1C12 T13 L20 F21C12-P17 WeakPolarHBondContact O-CD 3.44Å; T13-P17 WeakPolarHBondContact O-CG 3.42Å; P17-L20 PolarHBondContact O-N 3.25Å; P17-F21 VanDerWaalsContact O-CB 3.26Å; P17-F21 WeakPolarHBondContact O-CB 3.11Å; P17-F21 PolarHBondContact O-N 3.13Å
18L91.4Very high88.2Confident102 Ų10279.8 Ų79.853%0.53445%0.45SS..Hα-helixtrans-64-45.9175.5-179.563.7000111.4F14 V15 L16 F21 L22F14-L18 VanDerWaalsContact O-CB 3.29Å; F14-L18 WeakPolarHBondContact O-CB 3.33Å; F14-L18 PolarHBondContact O-N 3.17Å; V15-L18 PolarHBondContact O-N 2.92Å; L16-L18 VanDerWaalsContact C-N 3.32Å; L16-L18 PolarHBondContact O-N 3.28Å; L18-F21 PolarHBondContact O-N 3.23Å; L18-L22 HydrophobicContact CD1-CD1 4.43Å; L18-L22 HydrophobicContact CD1-CG 4.41Å; L18-L22 HydrophobicContact CG-CD1 4.2Å; L18-L22 WeakPolarHBondContact O-CB 3.4Å; L18-L22 VanDerWaalsContact O-CG 3.28Å; L18-L22 WeakPolarHBondContact O-CG 3.36Å; L18-L22 PolarHBondContact O-N 3.23Å
19L92Very high88.3Confident101 Ų10181.8 Ų81.853%0.52945%0.447SS..Hα-helixtrans-63.2-43176.9-72.6175.6000112V15 L16 F21 L22 A23V15-L19 HydrophobicContact CG1-CD1 3.97Å; V15-L19 HydrophobicContact CG1-CG 4.33Å; V15-L19 WeakPolarHBondContact O-CG 3.5Å; V15-L19 PolarHBondContact O-N 3.43Å; L16-L19 PolarHBondContact O-N 2.84Å; L19-F21 VanDerWaalsContact C-N 3.32Å; L19-F21 PolarHBondContact O-N 2.88Å; L19-L22 PolarHBondContact O-N 3.44Å; L19-A23 WeakPolarHBondContact O-CB 3.22Å; L19-A23 PolarHBondContact O-N 3.25Å
20L90.8Very high88.5Confident106 Ų10683.2 Ų83.256%0.55545%0.449SS*.Hα-helixtrans-62.5-40.3175.2-71.6174.8000111.5L16 P17 A23 A24L16-L20 HydrophobicContact CD1-CD1 4.4Å; L16-L20 HydrophobicContact CD1-CG 4.31Å; L16-L20 HydrophobicContact CG-CD1 4.13Å; L16-L20 HydrophobicContact CG-CG 4.46Å; L16-L20 WeakPolarHBondContact O-CB 3.45Å; L16-L20 WeakPolarHBondContact O-CG 3.28Å; L16-L20 PolarHBondContact O-N 3.38Å; P17-L20 PolarHBondContact O-N 3.25Å; L20-A23 PolarHBondContact O-N 2.99Å; L20-A24 VanDerWaalsContact O-CB 3.25Å; L20-A24 WeakPolarHBondContact O-CB 3.45Å; L20-A24 PolarHBondContact O-N 2.86Å
21F88.9Confident88.8Confident99 Ų9988.9 Ų88.943%0.43446%0.463SS..Hα-helixtrans-65-43.7175.2178.8-100.6000112.2P17 L18 L19 A24 T25 F51P17-F21 VanDerWaalsContact O-CB 3.26Å; P17-F21 WeakPolarHBondContact O-CB 3.11Å; P17-F21 PolarHBondContact O-N 3.13Å; L18-F21 PolarHBondContact O-N 3.23Å; L19-F21 VanDerWaalsContact C-N 3.32Å; L19-F21 PolarHBondContact O-N 2.88Å; F21-A24 PolarHBondContact O-N 3.38Å; F21-T25 HydrophobicContact CD1-CG2 4.28Å; F21-T25 HydrophobicContact CD2-CG2 4.46Å; F21-T25 HydrophobicContact CE1-CG2 3.86Å; F21-T25 HydrophobicContact CE2-CG2 4.07Å; F21-T25 HydrophobicContact CZ-CG2 3.74Å; F21-T25 WeakPolarHBondContact O-CB 3.43Å; F21-T25 VanDerWaalsContact O-CG2 3.25Å; F21-T25 WeakPolarHBondContact O-CG2 3.31Å; F21-T25 PolarHBondContact O-N 3.05Å; F21-T25 PolarHBondContact O-OG1 3.45Å; F21-F51 HydrophobicContact CE2-CD1 4.39Å; F21-F51 AromaticContact CZ-CD1 3.89Å; F21-F51 HydrophobicContact CZ-CD1 3.89Å; F21-F51 AromaticContact CZ-CE1 3.86Å; F21-F51 HydrophobicContact CZ-CE1 3.86Å
22L90.3Very high88.7Confident92 Ų9284.5 Ų84.548%0.48244%0.44SS..Hα-helixtrans-64.6-39.7175.3-69.4174.9000112L18 L19 T25 K26L18-L22 HydrophobicContact CD1-CD1 4.43Å; L18-L22 HydrophobicContact CD1-CG 4.41Å; L18-L22 HydrophobicContact CG-CD1 4.2Å; L18-L22 WeakPolarHBondContact O-CB 3.4Å; L18-L22 VanDerWaalsContact O-CG 3.28Å; L18-L22 WeakPolarHBondContact O-CG 3.36Å; L18-L22 PolarHBondContact O-N 3.23Å; L19-L22 PolarHBondContact O-N 3.44Å; L22-T25 VanDerWaalsContact CA-OG1 3.31Å; L22-T25 WeakPolarHBondContact CA-OG1 3.25Å; L22-T25 PolarHBondContact O-OG1 3.05Å; L22-K26 WeakPolarHBondContact O-CB 3.46Å; L22-K26 PolarHBondContact O-N 3.15Å
23A90.7Very high88.5Confident47 Ų4782 Ų8239%0.38842%0.422SS..Hα-helixtrans-64.7-46.5173.900000111.3L19 L20 T25 K26 L27L19-A23 WeakPolarHBondContact O-CB 3.22Å; L19-A23 PolarHBondContact O-N 3.25Å; L20-A23 PolarHBondContact O-N 2.99Å; A23-T25 PolarHBondContact O-N 2.73Å; A23-K26 PolarHBondContact O-N 2.99Å; A23-L27 WeakPolarHBondContact O-CB 3.26Å; A23-L27 WeakPolarHBondContact O-CG 3.41Å; A23-L27 PolarHBondContact O-N 3.01Å
24A88.4Confident88.5Confident45 Ų4581.7 Ų81.737%0.37242%0.423SS..Hα-helixtrans-61.3-43.4177.800000112L20 F21 W28L20-A24 VanDerWaalsContact O-CB 3.25Å; L20-A24 WeakPolarHBondContact O-CB 3.45Å; L20-A24 PolarHBondContact O-N 2.86Å; F21-A24 PolarHBondContact O-N 3.38Å; A24-W28 WeakPolarHBondContact O-CB 3.22Å; A24-W28 PolarHBondContact O-N 3Å
25T86.4Confident88.2Confident36 Ų3676.9 Ų76.922%0.22141%0.408CS..Hα-helixtrans-64.6-39.3175.352.60000112F21 L22 A23 Y29 P52F21-T25 HydrophobicContact CD1-CG2 4.28Å; F21-T25 HydrophobicContact CD2-CG2 4.46Å; F21-T25 HydrophobicContact CE1-CG2 3.86Å; F21-T25 HydrophobicContact CE2-CG2 4.07Å; F21-T25 HydrophobicContact CZ-CG2 3.74Å; F21-T25 WeakPolarHBondContact O-CB 3.43Å; F21-T25 VanDerWaalsContact O-CG2 3.25Å; F21-T25 WeakPolarHBondContact O-CG2 3.31Å; F21-T25 PolarHBondContact O-N 3.05Å; F21-T25 PolarHBondContact O-OG1 3.45Å; L22-T25 VanDerWaalsContact CA-OG1 3.31Å; L22-T25 WeakPolarHBondContact CA-OG1 3.25Å; L22-T25 PolarHBondContact O-OG1 3.05Å; A23-T25 PolarHBondContact O-N 2.73Å; T25-Y29 WeakPolarHBondContact O-CB 3.45Å; T25-Y29 PolarHBondContact O-N 2.91Å; T25-P52 HydrophobicContact CG2-CG 3.98Å
26K87.3Confident88.3Confident126 Ų12678.1 Ų78.155%0.54841%0.405SS..Hα-helixtrans-68.5-46.2176.2-169.469.7179.2-171.10112.3L22 A23 W28 Y29 L30L22-K26 WeakPolarHBondContact O-CB 3.46Å; L22-K26 PolarHBondContact O-N 3.15Å; A23-K26 PolarHBondContact O-N 2.99Å; K26-W28 VanDerWaalsContact C-N 3.32Å; K26-W28 PolarHBondContact O-N 2.87Å; K26-Y29 WeakPolarHBondContact O-CB 3.39Å; K26-Y29 PolarHBondContact O-N 2.95Å; K26-L30 HydrophobicContact CG-CD1 4.42Å; K26-L30 VanDerWaalsContact O-CG 3.32Å; K26-L30 WeakPolarHBondContact O-CG 3.26Å; K26-L30 PolarHBondContact O-N 3.48Å
27L89.6Confident88.3Confident117 Ų11776 Ų7661%0.61340%0.395SS*.Hα-helixtrans-61.9-41.7176-73.2173.6000111.2A23 L30 Y31A23-L27 WeakPolarHBondContact O-CB 3.26Å; A23-L27 WeakPolarHBondContact O-CG 3.41Å; A23-L27 PolarHBondContact O-N 3.01Å; L27-L30 PolarHBondContact O-N 3.45Å; L27-Y31 WeakPolarHBondContact O-CB 3.32Å; L27-Y31 PolarHBondContact O-N 3.44Å
28W86.8Confident88.4Confident27 Ų2783.7 Ų83.710%0.10242%0.415CS..Hα-helixtrans-59.6-48.1173.3176.1-108000112.1A24 K26 L30 Y31 C32 M49 F51 P52 F53 H82A24-W28 WeakPolarHBondContact O-CB 3.22Å; A24-W28 PolarHBondContact O-N 3Å; K26-W28 VanDerWaalsContact C-N 3.32Å; K26-W28 PolarHBondContact O-N 2.87Å; W28-L30 VanDerWaalsContact C-N 3.31Å; W28-L30 PolarHBondContact O-N 2.88Å; W28-Y31 HydrophobicContact CE3-CD1 4.22Å; W28-Y31 HydrophobicContact CZ3-CD1 4.12Å; W28-Y31 HydrophobicContact CZ3-CE1 4.3Å; W28-Y31 PolarHBondContact O-N 2.91Å; W28-C32 VanDerWaalsContact CE2-SG 3.51Å; W28-C32 WeakPolarHBondContact O-CB 3.27Å; W28-C32 PolarHBondContact O-N 2.95Å; W28-C32 PolarHBondContact O-SG 2.95Å; W28-C32 VanDerWaalsContact O-SG 3.41Å; W28-M49 PolarHBondContact NE1-O 3.42Å; W28-F51 PolarHBondContact NE1-O 3.39Å; W28-P52 HydrophobicContact CB-CB 4.03Å; W28-P52 HydrophobicContact CB-CG 3.89Å; W28-P52 HydrophobicContact CD2-CB 4.15Å; W28-P52 HydrophobicContact CE3-CB 4.44Å; W28-P52 HydrophobicContact CG-CB 3.95Å; W28-P52 HydrophobicContact CG-CG 4.11Å; W28-F53 VanDerWaalsContact CH2-CA 3.44Å; W28-F53 HydrophobicContact CH2-CD1 4.44Å; W28-F53 VanDerWaalsContact CH2-N 3.31Å; W28-F53 AromaticContact CZ3-CD1 3.9Å; W28-F53 HydrophobicContact CZ3-CD1 3.9Å; W28-F53 HydrophobicContact CZ3-CE1 4.23Å; W28-F53 HydrophobicContact CZ3-CG 4.31Å; W28-H82 AromaticContact CH2-CE1 3.89Å; W28-H82 AromaticContact CH2-NE2 3.78Å; W28-H82 AromaticContact CZ2-CD2 3.82Å; W28-H82 AromaticContact CZ2-CE1 3.51Å; W28-H82 AromaticContact CZ2-ND1 3.93Å; W28-H82 AromaticContact CZ2-NE2 3.45Å; W28-H82 WeakPolarHBondContact CZ2-NE2 3.48Å
29Y85.8Confident88.5Confident93 Ų9384 Ų8437%0.36543%0.426SS..Hα-helixtrans-58.2-45.1175.5175.6-95.3000111.4T25 K26 C32 V33 M49T25-Y29 WeakPolarHBondContact O-CB 3.45Å; T25-Y29 PolarHBondContact O-N 2.91Å; K26-Y29 WeakPolarHBondContact O-CB 3.39Å; K26-Y29 PolarHBondContact O-N 2.95Å; Y29-C32 PolarHBondContact O-N 2.99Å; Y29-V33 HydrophobicContact CD1-CG2 4.38Å; Y29-V33 HydrophobicContact CD2-CG2 4.23Å; Y29-V33 HydrophobicContact CE1-CG2 3.97Å; Y29-V33 HydrophobicContact CE2-CG2 3.8Å; Y29-V33 WeakPolarHBondContact O-CB 3.47Å; Y29-V33 VanDerWaalsContact O-CG2 3.31Å; Y29-V33 WeakPolarHBondContact O-CG2 3.23Å; Y29-V33 PolarHBondContact O-N 3.34Å; Y29-M49 HydrophobicContact CD2-CG 4.47Å
30L87Confident88.5Confident92 Ų9280.5 Ų80.548%0.48241%0.41SS..Hα-helixtrans-63.4-42.1177.5-70.9173.1000112K26 L27 W28 V33 S34K26-L30 HydrophobicContact CG-CD1 4.42Å; K26-L30 VanDerWaalsContact O-CG 3.32Å; K26-L30 WeakPolarHBondContact O-CG 3.26Å; K26-L30 PolarHBondContact O-N 3.48Å; L27-L30 PolarHBondContact O-N 3.45Å; W28-L30 VanDerWaalsContact C-N 3.31Å; W28-L30 PolarHBondContact O-N 2.88Å; L30-V33 PolarHBondContact O-N 3.19Å; L30-S34 VanDerWaalsContact O-CB 3.26Å; L30-S34 WeakPolarHBondContact O-CB 3.46Å; L30-S34 PolarHBondContact O-N 3.19Å; L30-S34 PolarHBondContact O-OG 3.43Å
31Y87Confident88.7Confident161 Ų16180.1 Ų80.163%0.63142%0.422SS*.Hα-helixtrans-61.4-45.9174.7171.1-99.5000111.9L27 W28 V33 S34L27-Y31 WeakPolarHBondContact O-CB 3.32Å; L27-Y31 PolarHBondContact O-N 3.44Å; W28-Y31 HydrophobicContact CE3-CD1 4.22Å; W28-Y31 HydrophobicContact CZ3-CD1 4.12Å; W28-Y31 HydrophobicContact CZ3-CE1 4.3Å; W28-Y31 PolarHBondContact O-N 2.91Å; Y31-V33 VanDerWaalsContact C-N 3.35Å; Y31-V33 PolarHBondContact O-N 3.04Å; Y31-S34 PolarHBondContact O-N 3.47Å; Y31-S34 PolarHBondContact O-OG 3.04Å
32C83.2Confident89.1Confident2 Ų277.7 Ų77.71%0.01441%0.413CS..Hα-helixtrans-64.4-41177.1-73.80000111.8W28 Y29 S35 M49W28-C32 VanDerWaalsContact CE2-SG 3.51Å; W28-C32 WeakPolarHBondContact O-CB 3.27Å; W28-C32 PolarHBondContact O-N 2.95Å; W28-C32 PolarHBondContact O-SG 2.95Å; W28-C32 VanDerWaalsContact O-SG 3.41Å; Y29-C32 PolarHBondContact O-N 2.99Å; C32-S35 PolarHBondContact O-OG 3.21Å; C32-M49 HydrophobicContact CB-CB 4.14Å; C32-M49 HydrophobicContact CB-CE 3.61Å; C32-M49 HydrophobicContact CB-CG 3.76Å
33V82.2Confident89.3Confident33 Ų3376.4 Ų76.420%0.241%0.411CS..Hα-helixtrans-80.3-22.1-178.8174.80000112.6Y29 L30 Y31 S35 R36 L44Y29-V33 HydrophobicContact CD1-CG2 4.38Å; Y29-V33 HydrophobicContact CD2-CG2 4.23Å; Y29-V33 HydrophobicContact CE1-CG2 3.97Å; Y29-V33 HydrophobicContact CE2-CG2 3.8Å; Y29-V33 WeakPolarHBondContact O-CB 3.47Å; Y29-V33 VanDerWaalsContact O-CG2 3.31Å; Y29-V33 WeakPolarHBondContact O-CG2 3.23Å; Y29-V33 PolarHBondContact O-N 3.34Å; L30-V33 PolarHBondContact O-N 3.19Å; Y31-V33 VanDerWaalsContact C-N 3.35Å; Y31-V33 PolarHBondContact O-N 3.04Å; V33-S35 PolarHBondContact O-N 3.47Å; V33-R36 WeakPolarHBondContact O-CB 3.17Å; V33-R36 PolarHBondContact O-N 3.34Å; V33-L44 HydrophobicContact CB-CD1 4.46Å; V33-L44 HydrophobicContact CG1-CD1 3.98Å; V33-L44 HydrophobicContact CG2-CD1 4.25Å
34S86.2Confident89.6Confident68 Ų6875 Ų7548%0.47640%0.396SS..Hα-helixtrans-65.8-18.7175.267.80000112.5L30 Y31 R36L30-S34 VanDerWaalsContact O-CB 3.26Å; L30-S34 WeakPolarHBondContact O-CB 3.46Å; L30-S34 PolarHBondContact O-N 3.19Å; L30-S34 PolarHBondContact O-OG 3.43Å; Y31-S34 PolarHBondContact O-N 3.47Å; Y31-S34 PolarHBondContact O-OG 3.04Å; S34-R36 PolarHBondContact O-N 2.65Å
35S84.8Confident90Very high49 Ų4972.9 Ų72.934%0.34338%0.379SS..THydrogen-bonded Turntrans-73.60.217073.50000114.3C32 V33 P391 W394C32-S35 PolarHBondContact O-OG 3.21Å; V33-S35 PolarHBondContact O-N 3.47Å; S35-P391 WeakPolarHBondContact O-CB 3.36Å; S35-W394 WeakPolarHBondContact OG-CZ2 3.2Å; S35-W394 PolarHBondContact OG-NE1 2.89Å
36R91.2Very high90.5Very high90 Ų9073 Ų7334%0.3438%0.38SS..SBendtrans-60.5143.1167.4-176.8-173.6172.4-168.6-5.9110V33 S34 R38 C40 A41 L42 L44 Q389V33-R36 WeakPolarHBondContact O-CB 3.17Å; V33-R36 PolarHBondContact O-N 3.34Å; S34-R36 PolarHBondContact O-N 2.65Å; R36-R38 PolarHBondContact O-N 2.7Å; R36-C40 PolarHBondContact NH2-O 3.16Å; R36-A41 PolarHBondContact NH2-O 2.63Å; R36-L42 PolarHBondContact NH2-O 2.9Å; R36-L44 HydrophobicContact CB-CD1 4.15Å; R36-L44 HydrophobicContact CB-CD2 4.26Å; R36-L44 HydrophobicContact CB-CG 4.24Å; R36-L44 HydrophobicContact CG-CD1 4.41Å; R36-L44 HydrophobicContact CG-CD2 4.12Å; R36-L44 HydrophobicContact CG-CG 4.01Å; R36-Q389 VanDerWaalsContact CG-CD 3.44Å
37D93.3Very high90.8Very high46 Ų4668 Ų6825%0.24636%0.364CS..  trans-75.9111.9169.3-166.2-24.7000110.5S39 C40 T382 Q389D37-S39 VanDerWaalsContact C-N 3.28Å; D37-S39 PolarHBondContact O-N 3.03Å; D37-S39 WeakPolarHBondContact OD1-CB 3.38Å; D37-S39 PolarHBondContact OD1-N 3.28Å; D37-S39 PolarHBondContact OD1-OG 3.47Å; D37-C40 HydrophobicContact CB-CB 4.21Å; D37-C40 PolarHBondContact O-N 3.48Å; D37-T382 HydrophobicContact CB-CG2 3.67Å; D37-T382 WeakPolarHBondContact CB-OG1 3.34Å; D37-T382 WeakPolarHBondContact OD2-CB 3.33Å; D37-T382 WeakPolarHBondContact OD2-CG2 3.4Å; D37-T382 PolarHBondContact OD2-OG1 2.87Å; D37-Q389 PolarHBondContact O-NE2 3.19Å; D37-Q389 PolarHBondContact O-OE1 2.7Å
38R92.2Very high91Very high226 Ų22664.8 Ų64.885%0.85335%0.349SS*.THydrogen-bonded Turntrans-72.8-20179.6-64.8-175.7-179.6-174.6-0.1113.1R36 C40R36-R38 PolarHBondContact O-N 2.7Å; R38-C40 VanDerWaalsContact C-N 3.26Å
39S93.5Very high91.2Very high107 Ų10763.7 Ų63.775%0.74835%0.345SS*.THydrogen-bonded Turntrans-76.5-17.5175.472.80000112.4D37D37-S39 VanDerWaalsContact C-N 3.28Å; D37-S39 PolarHBondContact O-N 3.03Å; D37-S39 WeakPolarHBondContact OD1-CB 3.38Å; D37-S39 PolarHBondContact OD1-N 3.28Å; D37-S39 PolarHBondContact OD1-OG 3.47Å
40C93.3Very high91.4Very high28 Ų2860.8 Ų60.819%0.18934%0.344CS..  trans-95.4117.8178.6-173.50000111.3R36 D37 R38 L42 T382 Q389R36-C40 PolarHBondContact NH2-O 3.16Å; D37-C40 HydrophobicContact CB-CB 4.21Å; D37-C40 PolarHBondContact O-N 3.48Å; R38-C40 VanDerWaalsContact C-N 3.26Å; C40-L42 PolarHBondContact O-N 3.2Å; C40-T382 HydrophobicContact CB-CG2 4.22Å; C40-Q389 HydrophobicContact CB-CB 4.33Å; C40-Q389 PolarHBondContact O-NE2 2.95Å
41A94.4Very high91.5Very high99 Ų9962.7 Ų62.782%0.81835%0.348SS*.  trans-63.1-27.8-18000000113.3R36R36-A41 PolarHBondContact NH2-O 2.63Å
42L96.8Very high91.4Very high47 Ų4756 Ų5625%0.24633%0.325CS..SBendtrans-64.3145.9-177.5-62175.6000112.1R36 C40 E384 Q389R36-L42 PolarHBondContact NH2-O 2.9Å; C40-L42 PolarHBondContact O-N 3.2Å; L42-E384 HydrophobicContact CD1-CB 3.66Å; L42-E384 HydrophobicContact CD1-CG 3.45Å; L42-E384 VanDerWaalsContact CD1-CG 3.45Å; L42-Q389 HydrophobicContact CB-CB 4.21Å; L42-Q389 WeakPolarHBondContact O-CG 3.31Å; L42-Q389 PolarHBondContact O-NE2 2.93Å
43P95.7Very high91.1Very high66 Ų6663 Ų6343%0.42936%0.355SS..PPolyproline II helixtrans-73163.1175.830-32.8000111.8Y388 Q389P43-Y388 HydrophobicContact CG-CD1 3.92Å; P43-Y388 HydrophobicContact CG-CE1 4.14Å; P43-Y388 WeakPolarHBondContact O-CA 3.32Å; P43-Q389 PolarHBondContact O-N 3.28Å
44L96.4Very high91.1Very high17 Ų1768.5 Ų68.59%0.08938%0.376CS..PPolyproline II helixtrans-67.8154.3164.7-69.5172.5000110.1V33 R36 K80 Y388 Q389 P391 W394V33-L44 HydrophobicContact CB-CD1 4.46Å; V33-L44 HydrophobicContact CG1-CD1 3.98Å; V33-L44 HydrophobicContact CG2-CD1 4.25Å; R36-L44 HydrophobicContact CB-CD1 4.15Å; R36-L44 HydrophobicContact CB-CD2 4.26Å; R36-L44 HydrophobicContact CB-CG 4.24Å; R36-L44 HydrophobicContact CG-CD1 4.41Å; R36-L44 HydrophobicContact CG-CD2 4.12Å; R36-L44 HydrophobicContact CG-CG 4.01Å; L44-K80 HydrophobicContact CB-CD 4.25Å; L44-K80 HydrophobicContact CD1-CD 4.5Å; L44-Y388 WeakPolarHBondContact O-CD1 3.38Å; L44-Q389 HydrophobicContact CD2-CG 4.1Å; L44-P391 HydrophobicContact CD2-CG 3.43Å; L44-P391 VanDerWaalsContact CD2-CG 3.43Å; L44-W394 HydrophobicContact CD1-CH2 4.06Å; L44-W394 HydrophobicContact CD1-CZ2 4.32Å; L44-W394 HydrophobicContact CD2-CH2 3.97Å; L44-W394 HydrophobicContact CD2-CZ2 4.08Å
45P97Very high91.4Very high0 Ų065.4 Ų65.40%036%0.355CS..PPolyproline II helixtrans-52.8152.2171.7-26.234.5000112.6I78 K80 V89 Y388 Q389 I390P45-I78 HydrophobicContact CB-CG1 4.22Å; P45-I78 HydrophobicContact CG-CD1 4.24Å; P45-I78 HydrophobicContact CG-CG1 4.21Å; P45-K80 HydrophobicContact CB-CB 4.46Å; P45-K80 WeakPolarHBondContact O-CD 3.33Å; P45-K80 VanDerWaalsContact O-CE 3.27Å; P45-K80 WeakPolarHBondContact O-CE 3.32Å; P45-K80 VanDerWaalsContact O-CG 3.31Å; P45-K80 WeakPolarHBondContact O-CG 3.25Å; P45-V89 HydrophobicContact CG-CG1 4.02Å; P45-V89 HydrophobicContact CG-CG2 4.34Å; P45-Y388 HydrophobicContact CB-CG 4.28Å; P45-Y388 HydrophobicContact CG-CG 4.15Å; P45-Q389 WeakPolarHBondContact CD-O 3.43Å; P45-I390 HydrophobicContact CG-CD1 4Å
46P96.6Very high91.8Very high40 Ų4063.7 Ų63.726%0.2634%0.342SS..SBendtrans-61.8157173.229.2-36.2000110.3Y75 I78 Y79 K80P46-Y75 HydrophobicContact CB-CD1 4.12Å; P46-I78 WeakPolarHBondContact CG-O 3.44Å; P46-Y79 CarbonylContact O-C 3.47Å; P46-Y79 WeakPolarHBondContact O-CA 3.4Å; P46-Y79 VanDerWaalsContact O-CB 3.23Å; P46-Y79 WeakPolarHBondContact O-CB 3.39Å; P46-K80 PolarHBondContact O-N 2.84Å
47G94.9Very high91.8Very high19 Ų1960.6 Ų60.620%0.19633%0.333CS..BIsolated β-bridgetrans134.7-174.7178.400000114.4K80G47-K80 WeakPolarHBondContact CA-O 3.47Å; G47-K80 WeakPolarHBondContact O-CE 3.41Å
48T91.8Very high91.6Very high50 Ų5064.1 Ų64.131%0.30735%0.351SS..  trans-130138.9-170.146.50000111.2G50 E56 K71 Y75 K80 T81T48-G50 VanDerWaalsContact C-N 3.25Å; T48-G50 PolarHBondContact O-N 3.25Å; T48-E56 PolarHBondContact OG1-OE1 3.12Å; T48-K71 PolarHBondContact OG1-NZ 3.11Å; T48-Y75 WeakPolarHBondContact CG2-OH 3.29Å; T48-K80 PolarHBondContact N-O 2.95Å; T48-T81 VanDerWaalsContact O-CA 3.3Å; T48-T81 WeakPolarHBondContact O-CA 3.28Å
49M91.6Very high91.5Very high5 Ų556.5 Ų56.53%0.02533%0.325CS..  trans-86.56.7178.2-55.7-53.3-107.100113.5W28 Y29 C32 G55 K80 H82 P87 W394W28-M49 PolarHBondContact NE1-O 3.42Å; Y29-M49 HydrophobicContact CD2-CG 4.47Å; C32-M49 HydrophobicContact CB-CB 4.14Å; C32-M49 HydrophobicContact CB-CE 3.61Å; C32-M49 HydrophobicContact CB-CG 3.76Å; M49-G55 WeakPolarHBondContact O-CA 3.22Å; M49-K80 HydrophobicContact SD-CB 4.39Å; M49-K80 HydrophobicContact SD-CD 4.15Å; M49-K80 HydrophobicContact SD-CG 4.2Å; M49-H82 HydrophobicContact CB-CB 4.37Å; M49-H82 VanDerWaalsContact O-CB 3.25Å; M49-H82 WeakPolarHBondContact O-CB 3.29Å; M49-P87 HydrophobicContact CE-CB 3.79Å; M49-P87 HydrophobicContact CE-CG 4.25Å; M49-W394 HydrophobicContact CE-CH2 3.45Å; M49-W394 VanDerWaalsContact CE-CH2 3.45Å; M49-W394 HydrophobicContact CE-CZ2 4.02Å; M49-W394 HydrophobicContact CE-CZ3 3.94Å; M49-W394 HydrophobicContact SD-CH2 4.5Å
50G90.8Very high91.4Very high32 Ų3253.2 Ų53.233%0.3330%0.299SS..  trans62.7-156.5177.500000114.3T48T48-G50 VanDerWaalsContact C-N 3.25Å; T48-G50 PolarHBondContact O-N 3.25Å
51F88.8Confident91Very high132 Ų13254.7 Ų54.758%0.57931%0.307SS*.BIsolated β-bridgetrans-72.4154.6178.2-67.1-72.7000111.8F21 W28 F53 G55F21-F51 HydrophobicContact CE2-CD1 4.39Å; F21-F51 AromaticContact CZ-CD1 3.89Å; F21-F51 HydrophobicContact CZ-CD1 3.89Å; F21-F51 AromaticContact CZ-CE1 3.86Å; F21-F51 HydrophobicContact CZ-CE1 3.86Å; W28-F51 PolarHBondContact NE1-O 3.39Å; F51-F53 PolarHBondContact O-N 3.22Å; F51-G55 PolarHBondContact N-O 2.78Å; F51-G55 VanDerWaalsContact O-CA 3.24Å; F51-G55 WeakPolarHBondContact O-CA 3.1Å; F51-G55 PolarHBondContact O-N 2.91Å
52P84.7Confident90.7Very high20 Ų2056.1 Ų56.113%0.1330%0.3CS..THydrogen-bonded Turntrans-50.7136.6173.3-27.635.5000112.9T25 W28 F54T25-P52 HydrophobicContact CG2-CG 3.98Å; W28-P52 HydrophobicContact CB-CB 4.03Å; W28-P52 HydrophobicContact CB-CG 3.89Å; W28-P52 HydrophobicContact CD2-CB 4.15Å; W28-P52 HydrophobicContact CE3-CB 4.44Å; W28-P52 HydrophobicContact CG-CB 3.95Å; W28-P52 HydrophobicContact CG-CG 4.11Å; P52-F54 WeakPolarHBondContact O-CD2 3.39Å; P52-F54 PolarHBondContact O-N 3.26Å
53F77.4Confident90.3Very high148 Ų14858 Ų5865%0.64931%0.308SS*.THydrogen-bonded Turntrans65.7-48.5-179.7-49.9-78.7000115.8W28 F51W28-F53 VanDerWaalsContact CH2-CA 3.44Å; W28-F53 HydrophobicContact CH2-CD1 4.44Å; W28-F53 VanDerWaalsContact CH2-N 3.31Å; W28-F53 AromaticContact CZ3-CD1 3.9Å; W28-F53 HydrophobicContact CZ3-CD1 3.9Å; W28-F53 HydrophobicContact CZ3-CE1 4.23Å; W28-F53 HydrophobicContact CZ3-CG 4.31Å; F51-F53 PolarHBondContact O-N 3.22Å
54F82.7Confident89.8Confident149 Ų14959.8 Ų59.865%0.65431%0.306SS*.THydrogen-bonded Turntrans-84.4-22.5-175.1-59.5-76.1000113.4P52 E56 T57P52-F54 WeakPolarHBondContact O-CD2 3.39Å; P52-F54 PolarHBondContact O-N 3.26Å; F54-E56 PolarHBondContact O-N 2.95Å; F54-T57 WeakPolarHBondContact O-CB 3.36Å; F54-T57 PolarHBondContact O-N 3.27Å; F54-T57 PolarHBondContact O-OG1 3.39Å
55G91.4Very high89.2Confident3 Ų367.2 Ų67.23%0.03133%0.333CS..BIsolated β-bridgetrans57.8-123.3-175.100000111.6M49 F51 H82M49-G55 WeakPolarHBondContact O-CA 3.22Å; F51-G55 PolarHBondContact N-O 2.78Å; F51-G55 VanDerWaalsContact O-CA 3.24Å; F51-G55 WeakPolarHBondContact O-CA 3.1Å; F51-G55 PolarHBondContact O-N 2.91Å; G55-H82 WeakPolarHBondContact CA-O 3.4Å
56E93.6Very high88.8Confident13 Ų1374.8 Ų74.86%0.06137%0.366CS..THydrogen-bonded Turntrans-114.713.6178.5-52.6-170.4129.800111.9T48 F54 L58 Q59 M60 F67 K71 T81 H82 L83T48-E56 PolarHBondContact OG1-OE1 3.12Å; F54-E56 PolarHBondContact O-N 2.95Å; E56-L58 PolarHBondContact O-N 2.8Å; E56-Q59 PolarHBondContact O-N 3.46Å; E56-M60 WeakPolarHBondContact O-CB 3.36Å; E56-M60 PolarHBondContact O-N 2.94Å; E56-F67 HydrophobicContact CB-CE2 3.95Å; E56-F67 HydrophobicContact CB-CZ 3.83Å; E56-K71 IonicContact OE1-NZ 3.6Å; E56-K71 PolarHBondContact OE1-NZ 3.23Å; E56-K71 VanDerWaalsContact OE2-CE 3.26Å; E56-K71 WeakPolarHBondContact OE2-CE 3.39Å; E56-K71 IonicContact OE2-NZ 3.29Å; E56-K71 PolarHBondContact OE2-NZ 2.92Å; E56-T81 PolarHBondContact OE2-OG1 3.4Å; E56-H82 PolarHBondContact N-O 2.95Å; E56-L83 HydrophobicContact CB-CD2 4.41Å
57T90.8Very high88.5Confident26 Ų2672.9 Ų72.916%0.1635%0.353CS..Hα-helixtrans-59.5-48.9-173.6-49.40000111.8F54 Q59 M60 V61 L83 F84F54-T57 WeakPolarHBondContact O-CB 3.36Å; F54-T57 PolarHBondContact O-N 3.27Å; F54-T57 PolarHBondContact O-OG1 3.39Å; T57-Q59 VanDerWaalsContact C-N 3.34Å; T57-Q59 PolarHBondContact O-N 3.49Å; T57-M60 WeakPolarHBondContact O-CB 3.48Å; T57-M60 PolarHBondContact O-N 2.91Å; T57-V61 WeakPolarHBondContact O-CG2 3.46Å; T57-V61 PolarHBondContact O-N 2.86Å; T57-L83 WeakPolarHBondContact OG1-CA 3.38Å; T57-F84 HydrophobicContact CG2-CD1 3.65Å; T57-F84 HydrophobicContact CG2-CE1 3.82Å; T57-F84 HydrophobicContact CG2-CG 4.38Å; T57-F84 PolarHBondContact OG1-N 2.93Å
58L89.3Confident88.3Confident120 Ų12073.5 Ų73.563%0.62835%0.352SS*.Hα-helixtrans-63.3-42.3-179.5-175.663.1000111.4E56 M60 V61 L62E56-L58 PolarHBondContact O-N 2.8Å; L58-M60 VanDerWaalsContact C-N 3.32Å; L58-M60 PolarHBondContact O-N 3.38Å; L58-V61 PolarHBondContact O-N 3.33Å; L58-L62 HydrophobicContact CD1-CD1 3.96Å; L58-L62 HydrophobicContact CD1-CG 4.12Å; L58-L62 HydrophobicContact CD2-CD1 4.48Å; L58-L62 HydrophobicContact CG-CD1 3.84Å; L58-L62 HydrophobicContact CG-CG 4.36Å; L58-L62 WeakPolarHBondContact O-CB 3.36Å; L58-L62 VanDerWaalsContact O-CG 3.31Å; L58-L62 WeakPolarHBondContact O-CG 3.49Å; L58-L62 PolarHBondContact O-N 3.4Å
59Q90.8Very high88.3Confident65 Ų6573.4 Ų73.430%0.30435%0.348SS..Hα-helixtrans-61.5-42.5175.8-169.9-1792.400111.2E56 T57 Q63 F67E56-Q59 PolarHBondContact O-N 3.46Å; T57-Q59 VanDerWaalsContact C-N 3.34Å; T57-Q59 PolarHBondContact O-N 3.49Å; Q59-Q63 HydrophobicContact CG-CG 4.3Å; Q59-Q63 VanDerWaalsContact O-CB 3.27Å; Q59-Q63 WeakPolarHBondContact O-CB 3.39Å; Q59-Q63 PolarHBondContact O-N 3.34Å; Q59-F67 HydrophobicContact CB-CD2 4.29Å; Q59-F67 HydrophobicContact CB-CE2 4.39Å; Q59-F67 HydrophobicContact CG-CD2 3.75Å; Q59-F67 HydrophobicContact CG-CE2 4.22Å
60M89.9Confident88.4Confident38 Ų3877.2 Ų77.219%0.18737%0.367CS..Hα-helixtrans-62.3-42.7175.4-172.4-125.270.600112E56 T57 L58 R64 F67 L83 F84E56-M60 WeakPolarHBondContact O-CB 3.36Å; E56-M60 PolarHBondContact O-N 2.94Å; T57-M60 WeakPolarHBondContact O-CB 3.48Å; T57-M60 PolarHBondContact O-N 2.91Å; L58-M60 VanDerWaalsContact C-N 3.32Å; L58-M60 PolarHBondContact O-N 3.38Å; M60-R64 WeakPolarHBondContact O-CA 3.14Å; M60-R64 PolarHBondContact O-N 3.19Å; M60-F67 HydrophobicContact CB-CD1 3.75Å; M60-F67 HydrophobicContact CB-CE1 3.76Å; M60-F67 HydrophobicContact CB-CG 4.33Å; M60-F67 HydrophobicContact CB-CZ 4.32Å; M60-F67 HydrophobicContact CG-CD1 3.7Å; M60-F67 HydrophobicContact CG-CE1 3.83Å; M60-L83 HydrophobicContact CB-CD2 3.91Å; M60-L83 HydrophobicContact CG-CD2 4.28Å; M60-L83 HydrophobicContact SD-CD1 4.49Å; M60-L83 HydrophobicContact SD-CD2 4.39Å; M60-F84 HydrophobicContact CE-CZ 4.04Å; M60-F84 HydrophobicContact SD-CE2 4.35Å; M60-F84 HydrophobicContact SD-CZ 3.92Å
61V86.3Confident88.6Confident60 Ų6076.2 Ų76.236%0.36435%0.353SS..Hα-helixtrans-67.6-41.7-179.5171.40000111.5T57 L58 R64T57-V61 WeakPolarHBondContact O-CG2 3.46Å; T57-V61 PolarHBondContact O-N 2.86Å; L58-V61 PolarHBondContact O-N 3.33Å; V61-R64 VanDerWaalsContact O-CG 3.23Å; V61-R64 WeakPolarHBondContact O-CG 3.29Å; V61-R64 PolarHBondContact O-NE 2.95Å
62L87.4Confident88.8Confident128 Ų12871.9 Ų71.967%0.6733%0.333SS*.Hα-helixtrans-76.5-44.1-178.2-66.4175.5000112.4L58L58-L62 HydrophobicContact CD1-CD1 3.96Å; L58-L62 HydrophobicContact CD1-CG 4.12Å; L58-L62 HydrophobicContact CD2-CD1 4.48Å; L58-L62 HydrophobicContact CG-CD1 3.84Å; L58-L62 HydrophobicContact CG-CG 4.36Å; L58-L62 WeakPolarHBondContact O-CB 3.36Å; L58-L62 VanDerWaalsContact O-CG 3.31Å; L58-L62 WeakPolarHBondContact O-CG 3.49Å; L58-L62 PolarHBondContact O-N 3.4Å
63Q87.8Confident89.2Confident88 Ų8880.8 Ų80.841%0.41136%0.364SS..Hα-helixtrans-96.1-18.9-173.4-61.6179.9-5.700113.8Q59 R65 K66 F67Q59-Q63 HydrophobicContact CG-CG 4.3Å; Q59-Q63 VanDerWaalsContact O-CB 3.27Å; Q59-Q63 WeakPolarHBondContact O-CB 3.39Å; Q59-Q63 PolarHBondContact O-N 3.34Å; Q63-R65 PolarHBondContact O-N 3.46Å; Q63-K66 HydrophobicContact CB-CB 4.42Å; Q63-K66 WeakPolarHBondContact O-CB 3.49Å; Q63-K66 PolarHBondContact O-N 2.86Å; Q63-F67 HydrophobicContact CB-CB 3.89Å
64R85.6Confident90.1Very high103 Ų10380.8 Ų80.839%0.38936%0.364SS..THydrogen-bonded Turntrans48.3-115.6173.3-55.7-177.6-179.6-120.22.5113.2M60 V61 K66 F67 L68 T478M60-R64 WeakPolarHBondContact O-CA 3.14Å; M60-R64 PolarHBondContact O-N 3.19Å; V61-R64 VanDerWaalsContact O-CG 3.23Å; V61-R64 WeakPolarHBondContact O-CG 3.29Å; V61-R64 PolarHBondContact O-NE 2.95Å; R64-K66 VanDerWaalsContact C-N 3.26Å; R64-K66 PolarHBondContact O-N 3.35Å; R64-F67 WeakPolarHBondContact O-CB 3.26Å; R64-F67 PolarHBondContact O-N 3.02Å; R64-F67 VanDerWaalsContact O-N 3.13Å; R64-L68 PolarHBondContact O-N 3.01Å; R64-T478 PolarHBondContact NH1-O 3.46Å
65R84.1Confident90.7Very high173 Ų17375.7 Ų75.765%0.65334%0.34SS*.Hα-helixtrans-57-37.7-178.8-170.4176.7-179-178.50.7112.2Q63 F67 L68 Q69Q63-R65 PolarHBondContact O-N 3.46Å; R65-F67 PolarHBondContact O-N 2.8Å; R65-L68 PolarHBondContact O-N 3.19Å; R65-Q69 HydrophobicContact CG-CG 4.35Å; R65-Q69 WeakPolarHBondContact O-CB 3.5Å; R65-Q69 WeakPolarHBondContact O-CG 3.39Å; R65-Q69 PolarHBondContact O-N 3.23Å
66K88.4Confident90.9Very high159 Ų15976.9 Ų76.969%0.69135%0.353SS*.Hα-helixtrans-62.8-42.7178.1-66.3-176.6177.9-179.30111.5Q63 R64 M70Q63-K66 HydrophobicContact CB-CB 4.42Å; Q63-K66 WeakPolarHBondContact O-CB 3.49Å; Q63-K66 PolarHBondContact O-N 2.86Å; R64-K66 VanDerWaalsContact C-N 3.26Å; R64-K66 PolarHBondContact O-N 3.35Å; K66-M70 VanDerWaalsContact O-CB 3.28Å; K66-M70 WeakPolarHBondContact O-CB 3.34Å; K66-M70 PolarHBondContact O-N 3.36Å
67F91.1Very high90.9Very high0 Ų081 Ų810%037%0.371CS..Hα-helixtrans-60.8-46.1175.8169.4-97.7000111.3E56 Q59 M60 Q63 R64 R65 M70 K71E56-F67 HydrophobicContact CB-CE2 3.95Å; E56-F67 HydrophobicContact CB-CZ 3.83Å; Q59-F67 HydrophobicContact CB-CD2 4.29Å; Q59-F67 HydrophobicContact CB-CE2 4.39Å; Q59-F67 HydrophobicContact CG-CD2 3.75Å; Q59-F67 HydrophobicContact CG-CE2 4.22Å; M60-F67 HydrophobicContact CB-CD1 3.75Å; M60-F67 HydrophobicContact CB-CE1 3.76Å; M60-F67 HydrophobicContact CB-CG 4.33Å; M60-F67 HydrophobicContact CB-CZ 4.32Å; M60-F67 HydrophobicContact CG-CD1 3.7Å; M60-F67 HydrophobicContact CG-CE1 3.83Å; Q63-F67 HydrophobicContact CB-CB 3.89Å; R64-F67 WeakPolarHBondContact O-CB 3.26Å; R64-F67 PolarHBondContact O-N 3.02Å; R64-F67 VanDerWaalsContact O-N 3.13Å; R65-F67 PolarHBondContact O-N 2.8Å; F67-M70 HydrophobicContact CD2-CE 4.16Å; F67-M70 PolarHBondContact O-N 3.22Å; F67-K71 HydrophobicContact CD2-CG 4.28Å; F67-K71 HydrophobicContact CE1-CG 4.2Å; F67-K71 HydrophobicContact CE2-CD 4.3Å; F67-K71 HydrophobicContact CE2-CG 4Å; F67-K71 HydrophobicContact CZ-CD 4.36Å; F67-K71 HydrophobicContact CZ-CG 3.94Å; F67-K71 WeakPolarHBondContact O-CB 3.5Å; F67-K71 VanDerWaalsContact O-CG 3.24Å; F67-K71 WeakPolarHBondContact O-CG 3.43Å; F67-K71 PolarHBondContact O-N 2.85Å
68L90.8Very high91.1Very high31 Ų3179.9 Ų79.916%0.16236%0.364CS..Hα-helixtrans-63.8-46.5179.7-60.3-177.1000112.4R64 R65 M70 K71 R72R64-L68 PolarHBondContact O-N 3.01Å; R65-L68 PolarHBondContact O-N 3.19Å; L68-M70 PolarHBondContact O-N 3.24Å; L68-K71 PolarHBondContact O-N 3.11Å; L68-R72 WeakPolarHBondContact O-CB 3.24Å; L68-R72 PolarHBondContact O-N 3.1Å
69Q90.5Very high91.5Very high49 Ų4974.2 Ų74.223%0.22933%0.334CS..Hα-helixtrans-61.4-44.2176.5-74.1175.4-23.300112.1R65 R72 R73R65-Q69 HydrophobicContact CG-CG 4.35Å; R65-Q69 WeakPolarHBondContact O-CB 3.5Å; R65-Q69 WeakPolarHBondContact O-CG 3.39Å; R65-Q69 PolarHBondContact O-N 3.23Å; Q69-R72 PolarHBondContact O-N 3.26Å; Q69-R73 WeakPolarHBondContact O-CB 3.31Å; Q69-R73 VanDerWaalsContact O-CG 3.3Å; Q69-R73 WeakPolarHBondContact O-CG 3.48Å; Q69-R73 PolarHBondContact O-N 3.3Å
70M94Very high91.8Very high85 Ų8571.9 Ų71.942%0.41932%0.323SS..Hα-helixtrans-60.3-46.9177179.5-167.36500111.3K66 F67 L68 R73 K74K66-M70 VanDerWaalsContact O-CB 3.28Å; K66-M70 WeakPolarHBondContact O-CB 3.34Å; K66-M70 PolarHBondContact O-N 3.36Å; F67-M70 HydrophobicContact CD2-CE 4.16Å; F67-M70 PolarHBondContact O-N 3.22Å; L68-M70 PolarHBondContact O-N 3.24Å; M70-R73 PolarHBondContact O-N 3.03Å; M70-K74 WeakPolarHBondContact O-CB 3.39Å; M70-K74 PolarHBondContact O-N 3.14Å; M70-K74 VanDerWaalsContact O-N 3.08Å
71K94.8Very high92Very high10 Ų1070 Ų704%0.04331%0.314CS..Hα-helixtrans-64.5-43.8179.6-69.9-71.3179171.60111.9T48 E56 F67 L68 K74 Y75 Y79T48-K71 PolarHBondContact OG1-NZ 3.11Å; E56-K71 IonicContact OE1-NZ 3.6Å; E56-K71 PolarHBondContact OE1-NZ 3.23Å; E56-K71 VanDerWaalsContact OE2-CE 3.26Å; E56-K71 WeakPolarHBondContact OE2-CE 3.39Å; E56-K71 IonicContact OE2-NZ 3.29Å; E56-K71 PolarHBondContact OE2-NZ 2.92Å; F67-K71 HydrophobicContact CD2-CG 4.28Å; F67-K71 HydrophobicContact CE1-CG 4.2Å; F67-K71 HydrophobicContact CE2-CD 4.3Å; F67-K71 HydrophobicContact CE2-CG 4Å; F67-K71 HydrophobicContact CZ-CD 4.36Å; F67-K71 HydrophobicContact CZ-CG 3.94Å; F67-K71 WeakPolarHBondContact O-CB 3.5Å; F67-K71 VanDerWaalsContact O-CG 3.24Å; F67-K71 WeakPolarHBondContact O-CG 3.43Å; F67-K71 PolarHBondContact O-N 2.85Å; L68-K71 PolarHBondContact O-N 3.11Å; K71-K74 PolarHBondContact O-N 3.43Å; K71-Y75 HydrophobicContact CB-CD2 4.5Å; K71-Y75 HydrophobicContact CD-CD2 3.98Å; K71-Y75 HydrophobicContact CD-CE2 3.66Å; K71-Y75 WeakPolarHBondContact O-CD2 3.3Å; K71-Y75 PolarHBondContact O-N 3.33Å; K71-Y79 HydrophobicContact CB-CD2 4.43Å; K71-Y79 HydrophobicContact CB-CE1 3.95Å; K71-Y79 HydrophobicContact CB-CE2 3.76Å; K71-Y79 VanDerWaalsContact CB-CZ 3.47Å; K71-Y79 WeakPolarHBondContact CB-OH 3.37Å; K71-Y79 HydrophobicContact CD-CE2 4.3Å; K71-Y79 HydrophobicContact CG-CE2 4.09Å
72R92.8Very high92.4Very high41 Ų4167.4 Ų67.416%0.15530%0.298CS..Hα-helixtrans-59.8-48.2175.5-176.1178.775.3-173.717.1111.9L68 Q69 K74 G76 M92 D402 D405L68-R72 WeakPolarHBondContact O-CB 3.24Å; L68-R72 PolarHBondContact O-N 3.1Å; Q69-R72 PolarHBondContact O-N 3.26Å; R72-K74 PolarHBondContact O-N 3.3Å; R72-G76 WeakPolarHBondContact O-CA 3.42Å; R72-G76 PolarHBondContact O-N 3.26Å; R72-M92 HydrophobicContact CB-CE 4.31Å; R72-M92 HydrophobicContact CB-SD 4.34Å; R72-M92 WeakPolarHBondContact CD-SD 3.48Å; R72-M92 HydrophobicContact CG-CE 4.11Å; R72-M92 HydrophobicContact CG-SD 3.52Å; R72-M92 VanDerWaalsContact CG-SD 3.52Å; R72-D402 IonicContact CZ-OD1 2.77Å; R72-D402 IonicContact NH1-OD1 2.8Å; R72-D402 PolarHBondContact NH1-OD1 2.99Å; R72-D405 IonicContact CZ-OD2 3.81Å; R72-D405 IonicContact NH1-OD2 3.6Å; R72-D405 PolarHBondContact NH1-OD2 2.96Å; R72-D405 IonicContact NH2-OD2 3.02Å; R72-D405 PolarHBondContact NH2-OD2 3.26Å
73R94.1Very high92.5Very high207 Ų20761.3 Ų61.378%0.78127%0.266SS*.Hα-helixtrans-59.1-35.8176.8-75.2176.6-177.7176.80.3112.3Q69 M70Q69-R73 WeakPolarHBondContact O-CB 3.31Å; Q69-R73 VanDerWaalsContact O-CG 3.3Å; Q69-R73 WeakPolarHBondContact O-CG 3.48Å; Q69-R73 PolarHBondContact O-N 3.3Å; M70-R73 PolarHBondContact O-N 3.03Å
74K96.3Very high92.4Very high148 Ų14862.3 Ų62.364%0.64327%0.269SS*.Hα-helixtrans-82.1-38.3-177.5-171.6172.7178.6177.40114.1M70 K71 R72M70-K74 WeakPolarHBondContact O-CB 3.39Å; M70-K74 PolarHBondContact O-N 3.14Å; M70-K74 VanDerWaalsContact O-N 3.08Å; K71-K74 PolarHBondContact O-N 3.43Å; R72-K74 PolarHBondContact O-N 3.3Å
75Y95.8Very high92.4Very high42 Ų4259.8 Ų59.817%0.16528%0.275CS..Hα-helixtrans-119-6.8-168.1-56.8-54.8000114.4P46 T48 K71 Y79P46-Y75 HydrophobicContact CB-CD1 4.12Å; T48-Y75 WeakPolarHBondContact CG2-OH 3.29Å; K71-Y75 HydrophobicContact CB-CD2 4.5Å; K71-Y75 HydrophobicContact CD-CD2 3.98Å; K71-Y75 HydrophobicContact CD-CE2 3.66Å; K71-Y75 WeakPolarHBondContact O-CD2 3.3Å; K71-Y75 PolarHBondContact O-N 3.33Å; Y75-Y79 HydrophobicContact CD2-CD2 4.34Å; Y75-Y79 HydrophobicContact CD2-CG 4.23Å
76G93.9Very high92.7Very high29 Ų2956.7 Ų56.730%0.29926%0.263SS..THydrogen-bonded Turntrans80.4-149.3179.100000113.9R72 I78R72-G76 WeakPolarHBondContact O-CA 3.42Å; R72-G76 PolarHBondContact O-N 3.26Å; G76-I78 VanDerWaalsContact C-N 3.33Å; G76-I78 PolarHBondContact O-N 3.08Å
77F93.9Very high92.9Very high99 Ų9950.5 Ų50.543%0.43424%0.239SC..THydrogen-bonded Turntrans-77.2-13.9-169.8-58.7-45.2000115.3M92 V406F77-M92 HydrophobicContact CB-CG 4.06Å; F77-M92 HydrophobicContact CD1-CG 3.92Å; F77-M92 HydrophobicContact CD1-SD 4.37Å; F77-M92 HydrophobicContact CG-CG 4.46Å; F77-M92 WeakPolarHBondContact O-CG 3.4Å; F77-M92 PolarHBondContact O-N 2.94Å; F77-V406 HydrophobicContact CD1-CB 4.37Å; F77-V406 HydrophobicContact CD1-CG1 4.33Å; F77-V406 HydrophobicContact CD1-CG2 4.08Å; F77-V406 HydrophobicContact CE1-CB 3.62Å; F77-V406 HydrophobicContact CE1-CG1 3.79Å; F77-V406 HydrophobicContact CE1-CG2 3.7Å; F77-V406 HydrophobicContact CZ-CB 4.4Å
78I96.5Very high93.1Very high3 Ų350.5 Ų50.52%0.01524%0.239CC..EExtended strand (participates in β ladder)trans-142.3126.8-179.6-168.4172.3000110P45 P46 G76 V89 R90 V91 L385 N386 Y388 I390P45-I78 HydrophobicContact CB-CG1 4.22Å; P45-I78 HydrophobicContact CG-CD1 4.24Å; P45-I78 HydrophobicContact CG-CG1 4.21Å; P46-I78 WeakPolarHBondContact CG-O 3.44Å; G76-I78 VanDerWaalsContact C-N 3.33Å; G76-I78 PolarHBondContact O-N 3.08Å; I78-V89 HydrophobicContact CD1-CG1 4.2Å; I78-V89 HydrophobicContact CG1-CG1 3.74Å; I78-R90 WeakPolarHBondContact CA-O 3.18Å; I78-V91 HydrophobicContact CG1-CG2 4.46Å; I78-L385 HydrophobicContact CD1-CB 4.2Å; I78-L385 HydrophobicContact CD1-CD2 3.84Å; I78-L385 HydrophobicContact CD1-CG 4.01Å; I78-N386 HydrophobicContact CD1-CB 4.34Å; I78-N386 HydrophobicContact CG2-CB 4.15Å; I78-N386 WeakPolarHBondContact CG2-ND2 3.44Å; I78-Y388 HydrophobicContact CD1-CD2 4.4Å; I78-Y388 HydrophobicContact CG2-CD2 3.62Å; I78-Y388 HydrophobicContact CG2-CE2 3.62Å; I78-I390 HydrophobicContact CD1-CD1 3.95Å
79Y97.1Very high93.4Very high0 Ų049 Ų490%023%0.232CC..EExtended strand (participates in β ladder)trans-153149.6178.267.9-92.6000113P46 K71 Y75 T81 V89 R90 M92P46-Y79 CarbonylContact O-C 3.47Å; P46-Y79 WeakPolarHBondContact O-CA 3.4Å; P46-Y79 VanDerWaalsContact O-CB 3.23Å; P46-Y79 WeakPolarHBondContact O-CB 3.39Å; K71-Y79 HydrophobicContact CB-CD2 4.43Å; K71-Y79 HydrophobicContact CB-CE1 3.95Å; K71-Y79 HydrophobicContact CB-CE2 3.76Å; K71-Y79 VanDerWaalsContact CB-CZ 3.47Å; K71-Y79 WeakPolarHBondContact CB-OH 3.37Å; K71-Y79 HydrophobicContact CD-CE2 4.3Å; K71-Y79 HydrophobicContact CG-CE2 4.09Å; Y75-Y79 HydrophobicContact CD2-CD2 4.34Å; Y75-Y79 HydrophobicContact CD2-CG 4.23Å; Y79-T81 HydrophobicContact CE2-CG2 4.21Å; Y79-V89 CarbonylContact O-C 3.57Å; Y79-V89 WeakPolarHBondContact O-CA 3.41Å; Y79-R90 HydrophobicContact CD1-CB 4.16Å; Y79-R90 HydrophobicContact CD2-CB 4.39Å; Y79-R90 HydrophobicContact CE1-CB 3.68Å; Y79-R90 HydrophobicContact CE1-CG 4.4Å; Y79-R90 HydrophobicContact CE2-CB 3.95Å; Y79-R90 HydrophobicContact CE2-CG 3.95Å; Y79-R90 HydrophobicContact CG-CB 4.49Å; Y79-R90 PolarHBondContact N-O 3.18Å; Y79-R90 VanDerWaalsContact N-O 3.15Å; Y79-R90 PolarHBondContact O-N 3.48Å; Y79-R90 WeakPolarHBondContact OH-CD 3.49Å; Y79-M92 HydrophobicContact CE1-CE 4.05Å
80K96.3Very high93.7Very high16 Ų1647.7 Ų47.77%0.0723%0.225CC..EExtended strand (participates in β ladder)trans-86.9145.6172.468.9-176.6174.1-173.90111.6L44 P45 P46 G47 T48 M49 T88 W394L44-K80 HydrophobicContact CB-CD 4.25Å; L44-K80 HydrophobicContact CD1-CD 4.5Å; P45-K80 HydrophobicContact CB-CB 4.46Å; P45-K80 WeakPolarHBondContact O-CD 3.33Å; P45-K80 VanDerWaalsContact O-CE 3.27Å; P45-K80 WeakPolarHBondContact O-CE 3.32Å; P45-K80 VanDerWaalsContact O-CG 3.31Å; P45-K80 WeakPolarHBondContact O-CG 3.25Å; P46-K80 PolarHBondContact O-N 2.84Å; G47-K80 WeakPolarHBondContact CA-O 3.47Å; G47-K80 WeakPolarHBondContact O-CE 3.41Å; T48-K80 PolarHBondContact N-O 2.95Å; M49-K80 HydrophobicContact SD-CB 4.39Å; M49-K80 HydrophobicContact SD-CD 4.15Å; M49-K80 HydrophobicContact SD-CG 4.2Å; K80-T88 CarbonylContact C-O 3.53Å; K80-T88 WeakPolarHBondContact CA-O 3.41Å; K80-W394 HydrophobicContact CB-CZ3 3.87Å; K80-W394 HydrophobicContact CD-CH2 4.4Å
81T95.3Very high93.9Very high0 Ų043.7 Ų43.70%021%0.205CC..EExtended strand (participates in β ladder)trans-151.3178.5172.2-176.50000109.3T48 E56 Y79 L83 T88 R90T48-T81 VanDerWaalsContact O-CA 3.3Å; T48-T81 WeakPolarHBondContact O-CA 3.28Å; E56-T81 PolarHBondContact OE2-OG1 3.4Å; Y79-T81 HydrophobicContact CE2-CG2 4.21Å; T81-L83 HydrophobicContact CG2-CD1 3.74Å; T81-L83 HydrophobicContact CG2-CG 3.75Å; T81-T88 HydrophobicContact CG2-CG2 4.32Å; T81-T88 PolarHBondContact N-O 3Å; T81-T88 PolarHBondContact O-N 3.22Å; T81-R90 HydrophobicContact CG2-CG 4.25Å
82H93.4Very high93.9Very high4 Ų443.2 Ų43.22%0.01920%0.203CC..EExtended strand (participates in β ladder)trans-124.7109.4172.3-169.2-81.4000108.6W28 M49 G55 E56 G85 R86W28-H82 AromaticContact CH2-CE1 3.89Å; W28-H82 AromaticContact CH2-NE2 3.78Å; W28-H82 AromaticContact CZ2-CD2 3.82Å; W28-H82 AromaticContact CZ2-CE1 3.51Å; W28-H82 AromaticContact CZ2-ND1 3.93Å; W28-H82 AromaticContact CZ2-NE2 3.45Å; W28-H82 WeakPolarHBondContact CZ2-NE2 3.48Å; M49-H82 HydrophobicContact CB-CB 4.37Å; M49-H82 VanDerWaalsContact O-CB 3.25Å; M49-H82 WeakPolarHBondContact O-CB 3.29Å; G55-H82 WeakPolarHBondContact CA-O 3.4Å; E56-H82 PolarHBondContact N-O 2.95Å; H82-G85 VanDerWaalsContact CE1-CA 3.49Å; H82-G85 WeakPolarHBondContact CE1-CA 3.28Å; H82-R86 WeakPolarHBondContact CA-O 3.33Å; H82-R86 PolarHBondContact CE1-N 3.41Å; H82-R86 VanDerWaalsContact CE1-N 3.33Å; H82-R86 PolarHBondContact NE2-N 3.14Å
83L90.5Very high94Very high1 Ų141.7 Ų41.71%0.00520%0.2CC..EExtended strand (participates in β ladder)trans-127.6139.4-175.4-65.6176000109.5E56 T57 M60 T81 G85 R86 T88 I397E56-L83 HydrophobicContact CB-CD2 4.41Å; T57-L83 WeakPolarHBondContact OG1-CA 3.38Å; M60-L83 HydrophobicContact CB-CD2 3.91Å; M60-L83 HydrophobicContact CG-CD2 4.28Å; M60-L83 HydrophobicContact SD-CD1 4.49Å; M60-L83 HydrophobicContact SD-CD2 4.39Å; T81-L83 HydrophobicContact CG2-CD1 3.74Å; T81-L83 HydrophobicContact CG2-CG 3.75Å; L83-G85 PolarHBondContact O-N 3.09Å; L83-R86 PolarHBondContact N-O 3.04Å; L83-R86 VanDerWaalsContact N-O 3.07Å; L83-R86 PolarHBondContact O-N 3.07Å; L83-T88 HydrophobicContact CD1-CG2 4.43Å; L83-I397 HydrophobicContact CD1-CD1 4.17Å
84F85.8Confident93.9Very high109 Ų10933 Ų3348%0.47817%0.172SC..THydrogen-bonded Turntrans53.141.8176.4-47.3-68.3000112.9T57 M60 R86 F376T57-F84 HydrophobicContact CG2-CD1 3.65Å; T57-F84 HydrophobicContact CG2-CE1 3.82Å; T57-F84 HydrophobicContact CG2-CG 4.38Å; T57-F84 PolarHBondContact OG1-N 2.93Å; M60-F84 HydrophobicContact CE-CZ 4.04Å; M60-F84 HydrophobicContact SD-CE2 4.35Å; M60-F84 HydrophobicContact SD-CZ 3.92Å; F84-R86 VanDerWaalsContact C-N 3.3Å; F84-R86 PolarHBondContact O-N 3.07Å; F84-F376 HydrophobicContact CE2-CE1 4.21Å
85G85.9Confident93.8Very high50 Ų5032 Ų3252%0.51517%0.174SC..THydrogen-bonded Turntrans76.310.2177.700000115.1H82 L83H82-G85 VanDerWaalsContact CE1-CA 3.49Å; H82-G85 WeakPolarHBondContact CE1-CA 3.28Å; L83-G85 PolarHBondContact O-N 3.09Å
86R89.3Confident93.8Very high108 Ų10830.8 Ų30.841%0.40817%0.17SC..EExtended strand (participates in β ladder)trans-134.9144.6-177.5-65.9-171.5175.4-173.30.5114.3H82 L83 F84 T88 N395H82-R86 WeakPolarHBondContact CA-O 3.33Å; H82-R86 PolarHBondContact CE1-N 3.41Å; H82-R86 VanDerWaalsContact CE1-N 3.33Å; H82-R86 PolarHBondContact NE2-N 3.14Å; L83-R86 PolarHBondContact N-O 3.04Å; L83-R86 VanDerWaalsContact N-O 3.07Å; L83-R86 PolarHBondContact O-N 3.07Å; F84-R86 VanDerWaalsContact C-N 3.3Å; F84-R86 PolarHBondContact O-N 3.07Å; R86-T88 PolarHBondContact O-N 3.22Å; R86-T88 PolarHBondContact O-OG1 3Å; R86-N395 WeakPolarHBondContact CB-ND2 3.41Å; R86-N395 WeakPolarHBondContact CD-OD1 3.26Å
87P93.9Very high93.9Very high29 Ų2929.4 Ų29.419%0.18816%0.156CC..EExtended strand (participates in β ladder)trans-52.7126.7162.3-25.535.4000110.6M49 W394 N395M49-P87 HydrophobicContact CE-CB 3.79Å; M49-P87 HydrophobicContact CE-CG 4.25Å; P87-W394 HydrophobicContact CB-CD2 3.51Å; P87-W394 HydrophobicContact CB-CE3 3.78Å; P87-W394 HydrophobicContact CB-CG 3.98Å; P87-W394 HydrophobicContact CB-CH2 4.18Å; P87-W394 HydrophobicContact CB-CZ2 3.9Å; P87-W394 HydrophobicContact CB-CZ3 4.12Å; P87-N395 PolarHBondContact O-N 3.35Å
88T95.1Very high93.9Very high0 Ų029.9 Ų29.90%016%0.155CC..EExtended strand (participates in β ladder)trans-136.4133.7-171-61.40000110.5K80 T81 L83 R86 N395 I397K80-T88 CarbonylContact C-O 3.53Å; K80-T88 WeakPolarHBondContact CA-O 3.41Å; T81-T88 HydrophobicContact CG2-CG2 4.32Å; T81-T88 PolarHBondContact N-O 3Å; T81-T88 PolarHBondContact O-N 3.22Å; L83-T88 HydrophobicContact CD1-CG2 4.43Å; R86-T88 PolarHBondContact O-N 3.22Å; R86-T88 PolarHBondContact O-OG1 3Å; T88-N395 CarbonylContact C-O 3.59Å; T88-N395 VanDerWaalsContact CA-O 3.31Å; T88-N395 WeakPolarHBondContact CA-O 3.19Å; T88-N395 HydrophobicContact CG2-CB 4.09Å; T88-N395 WeakPolarHBondContact OG1-CB 3.23Å; T88-I397 HydrophobicContact CG2-CB 4.49Å; T88-I397 HydrophobicContact CG2-CD1 3.59Å; T88-I397 HydrophobicContact CG2-CG1 3.69Å
89V97.3Very high93.9Very high0 Ų035 Ų350%017%0.174CC..EExtended strand (participates in β ladder)trans-102.5123.4167.8-173.30000108.7P45 I78 Y79 V91 I390 W394 N395 V396 I397P45-V89 HydrophobicContact CG-CG1 4.02Å; P45-V89 HydrophobicContact CG-CG2 4.34Å; I78-V89 HydrophobicContact CD1-CG1 4.2Å; I78-V89 HydrophobicContact CG1-CG1 3.74Å; Y79-V89 CarbonylContact O-C 3.57Å; Y79-V89 WeakPolarHBondContact O-CA 3.41Å; V89-V91 HydrophobicContact CG1-CG2 3.96Å; V89-I390 HydrophobicContact CG1-CD1 3.99Å; V89-I390 HydrophobicContact CG2-CD1 4.2Å; V89-I390 HydrophobicContact CG2-CG2 4.3Å; V89-W394 HydrophobicContact CG2-CE3 3.66Å; V89-W394 HydrophobicContact CG2-CZ3 4.16Å; V89-N395 PolarHBondContact N-O 3.02Å; V89-V396 CarbonylContact O-C 3.49Å; V89-V396 WeakPolarHBondContact O-CA 3.12Å; V89-I397 PolarHBondContact O-N 3.08Å
90R96.8Very high93.9Very high21 Ų2135 Ų358%0.07917%0.174CC..EExtended strand (participates in β ladder)trans-89.4136.7167.7-67.2-133.975177.8-3.8109.6I78 Y79 T81 I397I78-R90 WeakPolarHBondContact CA-O 3.18Å; Y79-R90 HydrophobicContact CD1-CB 4.16Å; Y79-R90 HydrophobicContact CD2-CB 4.39Å; Y79-R90 HydrophobicContact CE1-CB 3.68Å; Y79-R90 HydrophobicContact CE1-CG 4.4Å; Y79-R90 HydrophobicContact CE2-CB 3.95Å; Y79-R90 HydrophobicContact CE2-CG 3.95Å; Y79-R90 HydrophobicContact CG-CB 4.49Å; Y79-R90 PolarHBondContact N-O 3.18Å; Y79-R90 VanDerWaalsContact N-O 3.15Å; Y79-R90 PolarHBondContact O-N 3.48Å; Y79-R90 WeakPolarHBondContact OH-CD 3.49Å; T81-R90 HydrophobicContact CG2-CG 4.25Å; R90-I397 WeakPolarHBondContact CA-O 2.98Å
91V97.1Very high93.9Very high0 Ų034.3 Ų34.30%017%0.171CC..EExtended strand (participates in β ladder)trans-131.8133.5-173.5-176.90000109.6I78 V89 N96 V97 I100 L385 V396 I397 Y398 S399I78-V91 HydrophobicContact CG1-CG2 4.46Å; V89-V91 HydrophobicContact CG1-CG2 3.96Å; V91-N96 HydrophobicContact CG1-CB 3.47Å; V91-N96 VanDerWaalsContact CG1-CB 3.47Å; V91-V97 HydrophobicContact CG1-CG2 4.39Å; V91-I100 HydrophobicContact CG1-CG1 4.15Å; V91-L385 HydrophobicContact CG1-CD2 3.96Å; V91-L385 HydrophobicContact CG2-CD2 3.91Å; V91-V396 HydrophobicContact CG2-CG1 3.74Å; V91-I397 PolarHBondContact N-O 2.79Å; V91-Y398 CarbonylContact O-C 3.28Å; V91-Y398 VanDerWaalsContact O-CA 3.24Å; V91-Y398 WeakPolarHBondContact O-CA 3.32Å; V91-S399 PolarHBondContact O-N 3.18Å
92M95.5Very high93.9Very high1 Ų137.5 Ų37.51%0.00519%0.188CC..  trans-147173.2172.668.6-163.172.800110.4R72 F77 Y79 N96 D402R72-M92 HydrophobicContact CB-CE 4.31Å; R72-M92 HydrophobicContact CB-SD 4.34Å; R72-M92 WeakPolarHBondContact CD-SD 3.48Å; R72-M92 HydrophobicContact CG-CE 4.11Å; R72-M92 HydrophobicContact CG-SD 3.52Å; R72-M92 VanDerWaalsContact CG-SD 3.52Å; F77-M92 HydrophobicContact CB-CG 4.06Å; F77-M92 HydrophobicContact CD1-CG 3.92Å; F77-M92 HydrophobicContact CD1-SD 4.37Å; F77-M92 HydrophobicContact CG-CG 4.46Å; F77-M92 WeakPolarHBondContact O-CG 3.4Å; F77-M92 PolarHBondContact O-N 2.94Å; Y79-M92 HydrophobicContact CE1-CE 4.05Å; M92-N96 WeakPolarHBondContact O-CB 3.33Å; M92-N96 PolarHBondContact O-ND2 2.96Å; M92-D402 HydrophobicContact CB-CB 3.86Å; M92-D402 HydrophobicContact CE-CB 4.21Å; M92-D402 HydrophobicContact CG-CB 4.32Å; M92-D402 HydrophobicContact SD-CB 3.67Å
93G93.6Very high94Very high9 Ų937.3 Ų37.39%0.09319%0.187CC..SBendtrans89.4144.4-176.200000111.5D95 N96 V97 T403G93-D95 PolarHBondContact O-N 2.8Å; G93-N96 PolarHBondContact O-N 3.4Å; G93-V97 WeakPolarHBondContact O-CB 3.16Å; G93-V97 WeakPolarHBondContact O-CG2 2.93Å; G93-V97 PolarHBondContact O-N 3.08Å; G93-T403 PolarHBondContact N-OG1 3.34Å
94A92.8Very high94.2Very high23 Ų2337.6 Ų37.619%0.1919%0.188CC..Hα-helixtrans-46.3-59.6-172.100000113.5N96 V97 R98 R431 T433A94-N96 PolarHBondContact O-N 2.84Å; A94-V97 PolarHBondContact O-N 2.93Å; A94-R98 WeakPolarHBondContact O-CB 3.27Å; A94-R98 PolarHBondContact O-N 3.45Å; A94-R431 WeakPolarHBondContact CB-O 3.29Å; A94-T433 HydrophobicContact CB-CG2 4Å
95D93.6Very high94.5Very high128 Ų12834.2 Ų34.268%0.68417%0.174SC*.Hα-helixtrans-65.8-40.8-174.3-67.8-35.4000112.9G93 R98 R99G93-D95 PolarHBondContact O-N 2.8Å; D95-R98 WeakPolarHBondContact O-CB 3.48Å; D95-R98 PolarHBondContact O-N 3Å; D95-R99 WeakPolarHBondContact O-CB 3.23Å; D95-R99 PolarHBondContact O-N 2.71Å
96N95.6Very high95Very high16 Ų1638.8 Ų38.89%0.08618%0.175CC..Hα-helixtrans-66.5-48.2180-63.6-39.6000110.9V91 M92 G93 A94 R98 R99 I100 L385V91-N96 HydrophobicContact CG1-CB 3.47Å; V91-N96 VanDerWaalsContact CG1-CB 3.47Å; M92-N96 WeakPolarHBondContact O-CB 3.33Å; M92-N96 PolarHBondContact O-ND2 2.96Å; G93-N96 PolarHBondContact O-N 3.4Å; A94-N96 PolarHBondContact O-N 2.84Å; N96-R98 VanDerWaalsContact C-N 3.34Å; N96-R99 PolarHBondContact O-N 2.89Å; N96-I100 WeakPolarHBondContact O-CG1 3.5Å; N96-I100 PolarHBondContact O-N 2.84Å; N96-I100 VanDerWaalsContact O-N 3.08Å; N96-L385 HydrophobicContact CB-CD1 4.44Å
97V96.1Very high95.3Very high0 Ų033.8 Ų33.80%016%0.157CC..Hα-helixtrans-67.5-37.5179.4176.80000110.9V91 G93 A94 R99 I100 L101 Y398 T403 I435V91-V97 HydrophobicContact CG1-CG2 4.39Å; G93-V97 WeakPolarHBondContact O-CB 3.16Å; G93-V97 WeakPolarHBondContact O-CG2 2.93Å; G93-V97 PolarHBondContact O-N 3.08Å; A94-V97 PolarHBondContact O-N 2.93Å; V97-R99 VanDerWaalsContact C-N 3.34Å; V97-R99 PolarHBondContact O-N 2.94Å; V97-I100 PolarHBondContact O-N 3.26Å; V97-L101 HydrophobicContact CG1-CD1 3.59Å; V97-L101 HydrophobicContact CG1-CG 3.95Å; V97-L101 WeakPolarHBondContact O-CB 3.44Å; V97-L101 WeakPolarHBondContact O-CG 3.27Å; V97-L101 PolarHBondContact O-N 3.14Å; V97-Y398 HydrophobicContact CG1-CD2 3.8Å; V97-Y398 HydrophobicContact CG1-CG 4.32Å; V97-T403 VanDerWaalsContact CG2-OG1 3.29Å; V97-T403 WeakPolarHBondContact CG2-OG1 3.45Å; V97-I435 HydrophobicContact CB-CD1 4.38Å; V97-I435 HydrophobicContact CG1-CD1 3.44Å; V97-I435 VanDerWaalsContact CG1-CD1 3.44Å
98R95.4Very high95.5Very high110 Ų11032.4 Ų32.442%0.41515%0.148SC..Hα-helixtrans-54.4-49.3170.3-179.8173.7-172.4-75.1-2111.6A94 D95 N96 I100 L101 L102 F432A94-R98 WeakPolarHBondContact O-CB 3.27Å; A94-R98 PolarHBondContact O-N 3.45Å; D95-R98 WeakPolarHBondContact O-CB 3.48Å; D95-R98 PolarHBondContact O-N 3Å; N96-R98 VanDerWaalsContact C-N 3.34Å; R98-I100 VanDerWaalsContact C-N 3.33Å; R98-I100 PolarHBondContact O-N 2.67Å; R98-L101 PolarHBondContact O-N 3.11Å; R98-L102 HydrophobicContact CG-CD1 3.71Å; R98-L102 HydrophobicContact CG-CG 4.27Å; R98-L102 VanDerWaalsContact O-CB 3.31Å; R98-L102 WeakPolarHBondContact O-CB 3.43Å; R98-L102 WeakPolarHBondContact O-CG 3.36Å; R98-L102 PolarHBondContact O-N 3.4Å; R98-F432 HydrophobicContact CB-CB 3.92Å; R98-F432 HydrophobicContact CB-CD1 3.81Å; R98-F432 HydrophobicContact CB-CD2 3.76Å; R98-F432 HydrophobicContact CB-CE1 4.24Å; R98-F432 HydrophobicContact CB-CE2 4.19Å; R98-F432 HydrophobicContact CB-CG 3.55Å; R98-F432 HydrophobicContact CB-CZ 4.41Å; R98-F432 HydrophobicContact CG-CD1 4.27Å; R98-F432 HydrophobicContact CG-CD2 3.51Å; R98-F432 HydrophobicContact CG-CE1 4.34Å; R98-F432 HydrophobicContact CG-CE2 3.59Å; R98-F432 HydrophobicContact CG-CG 3.88Å; R98-F432 HydrophobicContact CG-CZ 4.01Å
99R96.4Very high95.5Very high109 Ų10932.8 Ų32.841%0.41115%0.151SC..Hα-helixtrans-61.5-40.9179.6-176.958.3171165.3-3.2112.3D95 N96 V97 G103 L107 L385D95-R99 WeakPolarHBondContact O-CB 3.23Å; D95-R99 PolarHBondContact O-N 2.71Å; N96-R99 PolarHBondContact O-N 2.89Å; V97-R99 VanDerWaalsContact C-N 3.34Å; V97-R99 PolarHBondContact O-N 2.94Å; R99-G103 WeakPolarHBondContact O-CA 3.39Å; R99-G103 PolarHBondContact O-N 3.31Å; R99-L107 HydrophobicContact CG-CD1 4.32Å; R99-L385 HydrophobicContact CB-CD1 3.82Å; R99-L385 HydrophobicContact CG-CD1 3.73Å
100I97.2Very high95.3Very high0 Ų033.3 Ų33.30%015%0.154CC..Hα-helixtrans-66-51.6176.6-66.8-55.2000111.2V91 N96 V97 R98 G103 E104 V108 R377 F383 L385 V396 Y398V91-I100 HydrophobicContact CG1-CG1 4.15Å; N96-I100 WeakPolarHBondContact O-CG1 3.5Å; N96-I100 PolarHBondContact O-N 2.84Å; N96-I100 VanDerWaalsContact O-N 3.08Å; V97-I100 PolarHBondContact O-N 3.26Å; R98-I100 VanDerWaalsContact C-N 3.33Å; R98-I100 PolarHBondContact O-N 2.67Å; I100-G103 WeakPolarHBondContact O-CA 3.14Å; I100-G103 PolarHBondContact O-N 2.68Å; I100-G103 VanDerWaalsContact O-N 3.09Å; I100-E104 PolarHBondContact O-N 2.81Å; I100-V108 HydrophobicContact CD1-CG1 4.22Å; I100-V108 HydrophobicContact CG2-CG2 4.27Å; I100-V108 VanDerWaalsContact O-CG2 3.32Å; I100-V108 WeakPolarHBondContact O-CG2 3.37Å; I100-R377 HydrophobicContact CG2-CG 4.22Å; I100-F383 HydrophobicContact CD1-CE2 3.93Å; I100-F383 HydrophobicContact CD1-CZ 3.73Å; I100-L385 HydrophobicContact CD1-CD2 3.88Å; I100-L385 HydrophobicContact CG1-CD2 4.11Å; I100-V396 HydrophobicContact CD1-CG1 3.89Å; I100-V396 HydrophobicContact CG1-CG1 4.2Å; I100-V396 HydrophobicContact CG2-CG1 4.37Å; I100-Y398 HydrophobicContact CG2-CD1 4.12Å; I100-Y398 HydrophobicContact CG2-CG 4.48Å
101L95.9Very high94.8Very high2 Ų235.1 Ų35.11%0.0116%0.163CC..Hα-helixtrans-67.5-41.1-175.7-69.5179.3000113.1V97 R98 G103 Y398 F432 I435 P441V97-L101 HydrophobicContact CG1-CD1 3.59Å; V97-L101 HydrophobicContact CG1-CG 3.95Å; V97-L101 WeakPolarHBondContact O-CB 3.44Å; V97-L101 WeakPolarHBondContact O-CG 3.27Å; V97-L101 PolarHBondContact O-N 3.14Å; R98-L101 PolarHBondContact O-N 3.11Å; L101-G103 PolarHBondContact O-N 2.86Å; L101-Y398 HydrophobicContact CD1-CE2 4.38Å; L101-Y398 HydrophobicContact CD2-CD1 4.22Å; L101-Y398 HydrophobicContact CD2-CD2 4.33Å; L101-Y398 HydrophobicContact CD2-CE1 3.73Å; L101-Y398 HydrophobicContact CD2-CE2 3.85Å; L101-Y398 HydrophobicContact CD2-CG 4.5Å; L101-Y398 HydrophobicContact CG-CE2 4.46Å; L101-F432 HydrophobicContact CB-CE1 4.05Å; L101-F432 HydrophobicContact CD1-CD1 4.16Å; L101-F432 HydrophobicContact CD1-CE1 3.84Å; L101-I435 HydrophobicContact CD1-CD1 4.14Å; L101-P441 WeakPolarHBondContact O-CD 3.31Å
102L95.2Very high94.3Very high67 Ų6738.3 Ų38.335%0.35118%0.176SC..THydrogen-bonded Turntrans-75.4-12.6173-61.5-177.2000112.9R98 E104 F432R98-L102 HydrophobicContact CG-CD1 3.71Å; R98-L102 HydrophobicContact CG-CG 4.27Å; R98-L102 VanDerWaalsContact O-CB 3.31Å; R98-L102 WeakPolarHBondContact O-CB 3.43Å; R98-L102 WeakPolarHBondContact O-CG 3.36Å; R98-L102 PolarHBondContact O-N 3.4Å; L102-E104 VanDerWaalsContact C-N 3.34Å; L102-F432 HydrophobicContact CD1-CE2 4.44Å; L102-F432 HydrophobicContact CD1-CZ 4.39Å; L102-F432 HydrophobicContact CD2-CZ 4.03Å; L102-F432 HydrophobicContact CG-CZ 4.03Å
103G95.6Very high93.9Very high0 Ų040.7 Ų40.70%019%0.191CC..THydrogen-bonded Turntrans-85.1-1.6176.600000114.2R99 I100 L101 H105 R106 L107 V108R99-G103 WeakPolarHBondContact O-CA 3.39Å; R99-G103 PolarHBondContact O-N 3.31Å; I100-G103 WeakPolarHBondContact O-CA 3.14Å; I100-G103 PolarHBondContact O-N 2.68Å; I100-G103 VanDerWaalsContact O-N 3.09Å; L101-G103 PolarHBondContact O-N 2.86Å; G103-H105 PolarHBondContact O-N 3.14Å; G103-R106 PolarHBondContact O-N 3.17Å; G103-R106 VanDerWaalsContact O-N 3.1Å; G103-L107 PolarHBondContact O-N 3.42Å; G103-V108 PolarHBondContact O-N 3.5Å
104E94.9Very high93.6Very high8 Ų842 Ų424%0.03720%0.201CC..BIsolated β-bridgetrans-53.3138.9177.3-171.877.5-168.700111.1I100 L102 R106 V108 V110 R377 P441 R442I100-E104 PolarHBondContact O-N 2.81Å; L102-E104 VanDerWaalsContact C-N 3.34Å; E104-R106 PolarHBondContact O-N 3.4Å; E104-V108 CarbonylContact C-O 3.56Å; E104-V108 WeakPolarHBondContact CA-O 3.28Å; E104-V110 PolarHBondContact OE1-N 3.21Å; E104-R377 WeakPolarHBondContact OE2-CD 3.32Å; E104-R377 IonicContact OE2-CZ 3.32Å; E104-R377 IonicContact OE2-NE 2.87Å; E104-R377 PolarHBondContact OE2-NE 3.46Å; E104-R377 IonicContact OE2-NH2 2.91Å; E104-P441 HydrophobicContact CB-CB 4.34Å; E104-P441 HydrophobicContact CB-CG 4.12Å; E104-P441 HydrophobicContact CG-CB 4.46Å; E104-R442 HydrophobicContact CG-CG 3.71Å; E104-R442 IonicContact OE1-CZ 3.53Å; E104-R442 IonicContact OE1-NE 2.93Å; E104-R442 PolarHBondContact OE1-NE 3.38Å; E104-R442 IonicContact OE1-NH2 3.71Å; E104-R442 PolarHBondContact OE1-NH2 2.94Å
105H92.3Very high93.5Very high37 Ų3741.1 Ų41.117%0.17119%0.193CC..THydrogen-bonded Turntrans72-4.9-177.5-50.2-66.1000115.1G103 V108 D130 H133G103-H105 PolarHBondContact O-N 3.14Å; H105-V108 PolarHBondContact N-O 3.39Å; H105-D130 WeakPolarHBondContact CB-OD1 3.37Å; H105-D130 PolarHBondContact CE1-N 3.38Å; H105-D130 IonicContact CE1-OD1 2.65Å; H105-D130 IonicContact CG-OD1 3.78Å; H105-D130 PolarHBondContact ND1-N 2.86Å; H105-D130 VanDerWaalsContact ND1-N 3.12Å; H105-D130 IonicContact ND1-OD1 3.55Å; H105-D130 PolarHBondContact ND1-OD1 3.46Å; H105-H133 AromaticContact NE2-ND1 3.65Å
106R94.9Very high93.4Very high146 Ų14635 Ų3555%0.55116%0.161SC*.THydrogen-bonded Turntrans-127.6-49-177.4179.3176.560.7177.4-7.7114G103 E104 K381G103-R106 PolarHBondContact O-N 3.17Å; G103-R106 VanDerWaalsContact O-N 3.1Å; E104-R106 PolarHBondContact O-N 3.4Å; R106-K381 WeakPolarHBondContact O-CE 3.32Å
107L96.9Very high93.1Very high4 Ų440 Ų402%0.02118%0.178CC..THydrogen-bonded Turntrans-100.8-41.4177.5-58.5-178.1000110.3R99 G103 L380 F383R99-L107 HydrophobicContact CG-CD1 4.32Å; G103-L107 PolarHBondContact O-N 3.42Å; L107-L380 PolarHBondContact O-N 3.02Å; L107-F383 HydrophobicContact CB-CD1 4.1Å; L107-F383 HydrophobicContact CB-CE1 4.11Å; L107-F383 HydrophobicContact CB-CG 4.43Å; L107-F383 HydrophobicContact CB-CZ 4.43Å; L107-F383 HydrophobicContact CD1-CD2 4.29Å; L107-F383 HydrophobicContact CD2-CB 4.05Å; L107-F383 HydrophobicContact CD2-CD1 4.42Å; L107-F383 HydrophobicContact CD2-CG 4.17Å
108V97.3Very high92.9Very high0 Ų043 Ų430%020%0.197CC..EExtended strand (participates in β ladder)trans-136.8159.1-175.8-63.50000111.1I100 G103 E104 H105 R377 V378 F383 V396I100-V108 HydrophobicContact CD1-CG1 4.22Å; I100-V108 HydrophobicContact CG2-CG2 4.27Å; I100-V108 VanDerWaalsContact O-CG2 3.32Å; I100-V108 WeakPolarHBondContact O-CG2 3.37Å; G103-V108 PolarHBondContact O-N 3.5Å; E104-V108 CarbonylContact C-O 3.56Å; E104-V108 WeakPolarHBondContact CA-O 3.28Å; H105-V108 PolarHBondContact N-O 3.39Å; V108-R377 HydrophobicContact CB-CB 4.04Å; V108-R377 HydrophobicContact CB-CG 4.35Å; V108-R377 HydrophobicContact CG1-CB 4.42Å; V108-R377 HydrophobicContact CG2-CB 4.41Å; V108-R377 HydrophobicContact CG2-CG 4.17Å; V108-V378 CarbonylContact C-O 3.59Å; V108-V378 WeakPolarHBondContact CA-O 3.47Å; V108-F383 HydrophobicContact CG1-CE1 3.98Å; V108-F383 HydrophobicContact CG1-CZ 3.98Å; V108-V396 HydrophobicContact CG1-CG2 4.48Å
109A95.7Very high92.9Very high8 Ų837.8 Ų37.87%0.06618%0.177CC..EExtended strand (participates in β ladder)trans-129.7148.2166.300000109.9R377 V378 L380A109-R377 VanDerWaalsContact C-CD 3.45Å; A109-R377 CarbonylContact O-C 3.47Å; A109-R377 WeakPolarHBondContact O-CA 3.31Å; A109-R377 WeakPolarHBondContact O-CD 3.4Å; A109-V378 HydrophobicContact CB-CG1 4.41Å; A109-V378 PolarHBondContact N-O 2.94Å; A109-V378 PolarHBondContact O-N 2.84Å; A109-L380 HydrophobicContact CB-CD1 4.15Å; A109-L380 HydrophobicContact CB-CD2 3.86Å; A109-L380 HydrophobicContact CB-CG 4.2Å
110V92.4Very high92.6Very high11 Ų1132.6 Ų32.67%0.06716%0.158CC..EExtended strand (participates in β ladder)trans-51.9140.3165.571.30000110.7E104 H129 R442E104-V110 PolarHBondContact OE1-N 3.21Å; V110-H129 PolarHBondContact O-CE1 2.88Å; V110-R442 VanDerWaalsContact CG1-NH2 3.3Å
111Q87.3Confident92.2Very high58 Ų5832.8 Ų32.827%0.27116%0.159SC..  trans-141.7104.7171.8-173.4166.138.500109.2V378Q111-V378 HydrophobicContact CB-CB 4.33Å; Q111-V378 HydrophobicContact CB-CG1 4.13Å
112W86.1Confident91.7Very high68 Ų6836.4 Ų36.426%0.25819%0.19SC..  trans-82.2150.8172.6-69.4102.6000111.1V116 R117 S126 F224W112-V116 HydrophobicContact CB-CB 4.11Å; W112-V116 HydrophobicContact CB-CG1 4.04Å; W112-V116 HydrophobicContact CD2-CG1 4.02Å; W112-V116 HydrophobicContact CE3-CB 4.37Å; W112-V116 HydrophobicContact CE3-CG1 3.8Å; W112-V116 HydrophobicContact CE3-CG2 4.22Å; W112-V116 HydrophobicContact CG-CG1 4.15Å; W112-R117 HydrophobicContact CB-CG 4Å; W112-S126 PolarHBondContact NE1-O 3.49Å; W112-F224 HydrophobicContact CZ3-CE1 4.34Å; W112-F224 AromaticContact CZ3-CZ 3.98Å; W112-F224 HydrophobicContact CZ3-CZ 3.98Å
113P86.3Confident91.3Very high50 Ų5033.9 Ų33.933%0.32518%0.18SC..  trans-53.6152.9169.4-24.734.5000112.1S115 V116 R117 F224P113-S115 VanDerWaalsContact C-N 3.28Å; P113-S115 PolarHBondContact O-N 3.47Å; P113-V116 HydrophobicContact CB-CG2 4.21Å; P113-V116 HydrophobicContact CG-CG2 4.13Å; P113-V116 PolarHBondContact O-N 3.26Å; P113-R117 PolarHBondContact O-N 3.07Å; P113-R117 VanDerWaalsContact O-N 3.13Å; P113-F224 HydrophobicContact CG-CD1 4.02Å; P113-F224 HydrophobicContact CG-CE1 4.2Å
114A88.7Confident91Very high38 Ų3833.9 Ų33.931%0.31418%0.18SC..Hα-helixtrans-57.7-40.4-179.200000112.5R117 T118 P227A114-R117 PolarHBondContact O-N 2.89Å; A114-T118 PolarHBondContact O-N 2.88Å; A114-T118 PolarHBondContact O-OG1 3.33Å; A114-T118 VanDerWaalsContact O-OG1 3.11Å; A114-P227 HydrophobicContact CB-CB 3.97Å
115S90.8Very high90.8Very high3 Ų334.1 Ų34.12%0.02118%0.182CC..Hα-helixtrans-58.3-47.8175.337.60000112.8P113 R117 T118 I119 L223 S225P113-S115 VanDerWaalsContact C-N 3.28Å; P113-S115 PolarHBondContact O-N 3.47Å; S115-R117 VanDerWaalsContact C-N 3.33Å; S115-R117 PolarHBondContact O-N 2.87Å; S115-T118 PolarHBondContact O-N 2.95Å; S115-I119 WeakPolarHBondContact O-CB 3.38Å; S115-I119 WeakPolarHBondContact O-CG1 3.32Å; S115-I119 PolarHBondContact O-N 3.17Å; S115-L223 CarbonylContact C-O 3.54Å; S115-L223 WeakPolarHBondContact CB-O 3.45Å; S115-L223 PolarHBondContact OG-O 3.14Å; S115-S225 WeakPolarHBondContact CB-O 3.45Å; S115-S225 PolarHBondContact OG-O 3.45Å
116V89.8Confident90.7Very high1 Ų133.4 Ų33.41%0.00618%0.181CC..Hα-helixtrans-58.6-45.2176.3178.70000111W112 P113 T118 I119 L120 L223 F224W112-V116 HydrophobicContact CB-CB 4.11Å; W112-V116 HydrophobicContact CB-CG1 4.04Å; W112-V116 HydrophobicContact CD2-CG1 4.02Å; W112-V116 HydrophobicContact CE3-CB 4.37Å; W112-V116 HydrophobicContact CE3-CG1 3.8Å; W112-V116 HydrophobicContact CE3-CG2 4.22Å; W112-V116 HydrophobicContact CG-CG1 4.15Å; P113-V116 HydrophobicContact CB-CG2 4.21Å; P113-V116 HydrophobicContact CG-CG2 4.13Å; P113-V116 PolarHBondContact O-N 3.26Å; V116-T118 VanDerWaalsContact C-N 3.35Å; V116-T118 PolarHBondContact O-N 3.3Å; V116-I119 PolarHBondContact O-N 2.85Å; V116-L120 HydrophobicContact CG1-CD1 3.74Å; V116-L120 HydrophobicContact CG1-CG 4.29Å; V116-L120 WeakPolarHBondContact O-CB 3.3Å; V116-L120 PolarHBondContact O-N 3.45Å; V116-L223 WeakPolarHBondContact CA-O 3.3Å; V116-L223 HydrophobicContact CG1-CD2 4.48Å; V116-L223 HydrophobicContact CG2-CB 4.28Å; V116-L223 WeakPolarHBondContact CG2-O 3.3Å; V116-L223 PolarHBondContact N-O 2.89Å; V116-F224 HydrophobicContact CG2-CD1 4.03Å; V116-F224 HydrophobicContact CG2-CE1 3.96Å; V116-F224 HydrophobicContact CG2-CG 4.38Å; V116-F224 HydrophobicContact CG2-CZ 4.25Å
117R90.8Very high90.4Very high119 Ų11927.2 Ų27.245%0.44916%0.158SC..Hα-helixtrans-63.4-40.7179.4-62.7-174-55.3-1795.2112.3W112 P113 A114 S115 G121 N127W112-R117 HydrophobicContact CB-CG 4Å; P113-R117 PolarHBondContact O-N 3.07Å; P113-R117 VanDerWaalsContact O-N 3.13Å; A114-R117 PolarHBondContact O-N 2.89Å; S115-R117 VanDerWaalsContact C-N 3.33Å; S115-R117 PolarHBondContact O-N 2.87Å; R117-G121 CarbonylContact O-C 3.58Å; R117-G121 VanDerWaalsContact O-C 3.28Å; R117-G121 WeakPolarHBondContact O-CA 3.34Å; R117-G121 PolarHBondContact O-N 3.04Å; R117-N127 WeakPolarHBondContact CG-OD1 3.42Å
118T92.4Very high90.1Very high64 Ų6428.3 Ų28.339%0.39316%0.164SC..Hα-helixtrans-70.3-43.7178.6-60.80000111.7A114 S115 V116 L235 V239 R242A114-T118 PolarHBondContact O-N 2.88Å; A114-T118 PolarHBondContact O-OG1 3.33Å; A114-T118 VanDerWaalsContact O-OG1 3.11Å; S115-T118 PolarHBondContact O-N 2.95Å; V116-T118 VanDerWaalsContact C-N 3.35Å; V116-T118 PolarHBondContact O-N 3.3Å; T118-L235 HydrophobicContact CG2-CD1 4.02Å; T118-V239 HydrophobicContact CG2-CG2 3.96Å; T118-R242 PolarHBondContact O-NH1 3.18Å
119I93.4Very high89.8Confident0 Ų031.6 Ų31.60%018%0.18CC..Hα-helixtrans-75.5-42.4-176.6-66.2166.4000111.8S115 V116 M219 N222 L223 L235 V239 R242S115-I119 WeakPolarHBondContact O-CB 3.38Å; S115-I119 WeakPolarHBondContact O-CG1 3.32Å; S115-I119 PolarHBondContact O-N 3.17Å; V116-I119 PolarHBondContact O-N 2.85Å; I119-M219 HydrophobicContact CG2-CG 3.46Å; I119-M219 VanDerWaalsContact CG2-CG 3.46Å; I119-M219 HydrophobicContact CG2-SD 4.33Å; I119-N222 HydrophobicContact CD1-CB 4.3Å; I119-N222 WeakPolarHBondContact CD1-O 3.24Å; I119-L223 HydrophobicContact CB-CD2 3.95Å; I119-L223 HydrophobicContact CG2-CD2 3.66Å; I119-L235 HydrophobicContact CD1-CD1 3.92Å; I119-L235 HydrophobicContact CG1-CD1 3.76Å; I119-V239 HydrophobicContact CG1-CG2 4.18Å; I119-R242 WeakPolarHBondContact O-CD 3.25Å; I119-R242 WeakPolarHBondContact O-CG 3.37Å
120L90.2Very high89.6Confident1 Ų135.1 Ų35.11%0.00520%0.197CC..Hα-helixtrans-74.7-37.5176.2-68179.7000111.8V116 C124 L223 F301V116-L120 HydrophobicContact CG1-CD1 3.74Å; V116-L120 HydrophobicContact CG1-CG 4.29Å; V116-L120 WeakPolarHBondContact O-CB 3.3Å; V116-L120 PolarHBondContact O-N 3.45Å; L120-C124 VanDerWaalsContact C-SG 3.55Å; L120-C124 PolarHBondContact O-SG 2.97Å; L120-L223 HydrophobicContact CD1-CD2 4.33Å; L120-L223 HydrophobicContact CD2-CD2 3.81Å; L120-L223 HydrophobicContact CG-CD2 3.67Å; L120-F301 HydrophobicContact CD1-CD1 4.19Å; L120-F301 HydrophobicContact CD1-CE1 4.33Å; L120-F301 HydrophobicContact CD2-CB 4.38Å; L120-F301 HydrophobicContact CD2-CD1 4.38Å; L120-F301 HydrophobicContact CD2-CG 4.26Å
121G88.8Confident89.5Confident3 Ų339 Ų393%0.03123%0.225CC..  trans113146.8-174.900000111.8R117 G123 C124 N127R117-G121 CarbonylContact O-C 3.58Å; R117-G121 VanDerWaalsContact O-C 3.28Å; R117-G121 WeakPolarHBondContact O-CA 3.34Å; R117-G121 PolarHBondContact O-N 3.04Å; G121-G123 VanDerWaalsContact C-N 3.3Å; G121-G123 PolarHBondContact O-N 2.86Å; G121-C124 PolarHBondContact O-N 3.38Å; G121-N127 PolarHBondContact O-ND2 3Å
122A86.3Confident89.6Confident78 Ų7838.3 Ų38.365%0.64523%0.227SC*.THydrogen-bonded Turntrans-72.1-23.9-173.700000113.1
123G86.9Confident89.9Confident15 Ų1535.3 Ų35.316%0.15522%0.215CC..THydrogen-bonded Turntrans-92.52.4179.200000115G121 L128 E294G121-G123 VanDerWaalsContact C-N 3.3Å; G121-G123 PolarHBondContact O-N 2.86Å; G123-L128 WeakPolarHBondContact O-CD1 3.46Å; G123-E294 VanDerWaalsContact C-OE2 3.28Å; G123-E294 WeakPolarHBondContact CA-OE2 3.49Å; G123-E294 PolarHBondContact N-OE2 3.44Å
124C89.8Confident90.2Very high0 Ų039.3 Ų39.30%023%0.228CC..SBendtrans-60.3143.5168.1-68.30000111.1L120 G121 S126 N127 L128 E294 E298L120-C124 VanDerWaalsContact C-SG 3.55Å; L120-C124 PolarHBondContact O-SG 2.97Å; G121-C124 PolarHBondContact O-N 3.38Å; C124-S126 PolarHBondContact O-N 3.45Å; C124-S126 VanDerWaalsContact O-N 3.15Å; C124-N127 CarbonylContact O-C 3.58Å; C124-N127 WeakPolarHBondContact O-CA 3.19Å; C124-N127 PolarHBondContact O-N 2.93Å; C124-L128 WeakPolarHBondContact O-CG 3.16Å; C124-L128 PolarHBondContact O-N 3.46Å; C124-E294 PolarHBondContact SG-O 3.48Å; C124-E298 HydrophobicContact CB-CB 4.37Å
125L90.7Very high90.2Very high13 Ų1341.8 Ų41.87%0.06823%0.233CC..THydrogen-bonded Turntrans-51.5-40.9179.3-175.268.5000112.7N127 L128 H133 R136 K137 I140 E298 R442 V445L125-N127 PolarHBondContact O-N 3.24Å; L125-L128 PolarHBondContact O-N 3.08Å; L125-H133 WeakPolarHBondContact CD1-CD2 3.23Å; L125-H133 WeakPolarHBondContact CD1-O 3.44Å; L125-H133 PolarHBondContact O-CD2 3.39Å; L125-H133 VanDerWaalsContact O-CD2 3.27Å; L125-R136 HydrophobicContact CB-CG 4.27Å; L125-R136 HydrophobicContact CD1-CB 3.73Å; L125-R136 HydrophobicContact CD1-CG 3.76Å; L125-K137 HydrophobicContact CD1-CB 3.81Å; L125-K137 HydrophobicContact CD2-CB 4.38Å; L125-I140 HydrophobicContact CB-CD1 4.1Å; L125-I140 HydrophobicContact CD2-CD1 4.05Å; L125-I140 HydrophobicContact CG-CD1 4.47Å; L125-E298 WeakPolarHBondContact CA-OE2 3.42Å; L125-E298 WeakPolarHBondContact CB-OE2 3.27Å; L125-E298 PolarHBondContact N-OE1 3.36Å; L125-E298 PolarHBondContact N-OE2 3.42Å; L125-R442 PolarHBondContact O-NH1 2.91Å; L125-V445 HydrophobicContact CD2-CG1 3.8Å
126S88.6Confident90.2Very high22 Ų2243.2 Ų43.215%0.15424%0.238CC..THydrogen-bonded Turntrans-60.8-26.3176.948.80000113.7W112 C124 E298W112-S126 PolarHBondContact NE1-O 3.49Å; C124-S126 PolarHBondContact O-N 3.45Å; C124-S126 VanDerWaalsContact O-N 3.15Å; S126-E298 WeakPolarHBondContact CA-OE1 3.38Å; S126-E298 WeakPolarHBondContact CB-OE1 3.28Å; S126-E298 PolarHBondContact N-OE1 3.19Å; S126-E298 PolarHBondContact OG-OE1 3.49Å
127N89.6Confident90.3Very high15 Ų1544.6 Ų44.68%0.0824%0.244CC..THydrogen-bonded Turntrans-103.4-18.6-179.9-65.9-33.1000113.5R117 G121 C124 L125 H129R117-N127 WeakPolarHBondContact CG-OD1 3.42Å; G121-N127 PolarHBondContact O-ND2 3Å; C124-N127 CarbonylContact O-C 3.58Å; C124-N127 WeakPolarHBondContact O-CA 3.19Å; C124-N127 PolarHBondContact O-N 2.93Å; L125-N127 PolarHBondContact O-N 3.24Å; N127-H129 PolarHBondContact O-CD2 3.29Å; N127-H129 PolarHBondContact O-NE2 3.04Å
128L91.1Very high90.2Very high28 Ų2844.1 Ų44.115%0.14725%0.245CC..  trans-69.4156.7174-69.5179.4000111.9G123 C124 L125 H133 R136 R442G123-L128 WeakPolarHBondContact O-CD1 3.46Å; C124-L128 WeakPolarHBondContact O-CG 3.16Å; C124-L128 PolarHBondContact O-N 3.46Å; L125-L128 PolarHBondContact O-N 3.08Å; L128-H133 HydrophobicContact CB-CB 3.98Å; L128-R136 HydrophobicContact CD1-CB 3.62Å; L128-R136 HydrophobicContact CD1-CG 3.87Å; L128-R442 VanDerWaalsContact O-CZ 3.23Å; L128-R442 PolarHBondContact O-NH1 3.46Å; L128-R442 PolarHBondContact O-NH2 3.2Å
129H91.3Very high90Very high69 Ų6941.2 Ų41.232%0.31923%0.227SC..  trans-132.2160.8179.4-66.8-83.4000112.5V110 N127 S131 S132 H133 R442V110-H129 PolarHBondContact O-CE1 2.88Å; N127-H129 PolarHBondContact O-CD2 3.29Å; N127-H129 PolarHBondContact O-NE2 3.04Å; H129-S131 PolarHBondContact O-N 2.88Å; H129-S132 PolarHBondContact N-OG 3.42Å; H129-S132 PolarHBondContact O-N 3.31Å; H129-S132 PolarHBondContact O-OG 2.84Å; H129-H133 PolarHBondContact O-N 3.45Å; H129-H133 VanDerWaalsContact O-N 3.12Å; H129-R442 PolarHBondContact ND1-NH2 3.47Å
130D89.6Confident89.9Confident81 Ų8141.3 Ų41.343%0.43323%0.227SC..Hα-helixtrans49.5-123.5170.9-49.6-34.8000113.9H105 H133 K134H105-D130 WeakPolarHBondContact CB-OD1 3.37Å; H105-D130 PolarHBondContact CE1-N 3.38Å; H105-D130 IonicContact CE1-OD1 2.65Å; H105-D130 IonicContact CG-OD1 3.78Å; H105-D130 PolarHBondContact ND1-N 2.86Å; H105-D130 VanDerWaalsContact ND1-N 3.12Å; H105-D130 IonicContact ND1-OD1 3.55Å; H105-D130 PolarHBondContact ND1-OD1 3.46Å; D130-H133 PolarHBondContact O-N 3.44Å; D130-K134 WeakPolarHBondContact O-CG 3.13Å; D130-K134 PolarHBondContact O-N 3.19Å; D130-K134 VanDerWaalsContact O-N 3.12Å
131S90.3Very high90Very high92 Ų9244.7 Ų44.764%0.64324%0.244SC*.Hα-helixtrans-63.2-43.3-179.251.20000112.4H129 H133 K134 Q135H129-S131 PolarHBondContact O-N 2.88Å; S131-H133 VanDerWaalsContact C-N 3.31Å; S131-H133 PolarHBondContact O-N 2.96Å; S131-K134 PolarHBondContact O-N 2.86Å; S131-K134 VanDerWaalsContact O-N 3.14Å; S131-Q135 WeakPolarHBondContact O-CB 3.25Å; S131-Q135 PolarHBondContact O-N 3.42Å
132S90.4Very high89.9Confident45 Ų4547.8 Ų47.832%0.31526%0.258SS..Hα-helixtrans-60.5-41.5-179.967.20000111.8H129 R136H129-S132 PolarHBondContact N-OG 3.42Å; H129-S132 PolarHBondContact O-N 3.31Å; H129-S132 PolarHBondContact O-OG 2.84Å; S132-R136 WeakPolarHBondContact O-CB 3.4Å; S132-R136 PolarHBondContact O-N 2.68Å
133H93.3Very high90.1Very high5 Ų544 Ų442%0.02323%0.227CC..Hα-helixtrans-63.2-47.9173.5170.8-104000111.8H105 L125 L128 H129 D130 S131 Q135 R136 K137 P441 R442H105-H133 AromaticContact NE2-ND1 3.65Å; L125-H133 WeakPolarHBondContact CD1-CD2 3.23Å; L125-H133 WeakPolarHBondContact CD1-O 3.44Å; L125-H133 PolarHBondContact O-CD2 3.39Å; L125-H133 VanDerWaalsContact O-CD2 3.27Å; L128-H133 HydrophobicContact CB-CB 3.98Å; H129-H133 PolarHBondContact O-N 3.45Å; H129-H133 VanDerWaalsContact O-N 3.12Å; D130-H133 PolarHBondContact O-N 3.44Å; S131-H133 VanDerWaalsContact C-N 3.31Å; S131-H133 PolarHBondContact O-N 2.96Å; H133-Q135 VanDerWaalsContact C-N 3.33Å; H133-Q135 PolarHBondContact O-N 2.69Å; H133-R136 PolarHBondContact O-N 2.72Å; H133-K137 VanDerWaalsContact O-CB 3.23Å; H133-K137 WeakPolarHBondContact O-CB 3.46Å; H133-K137 PolarHBondContact O-N 3.4Å; H133-P441 PolarHBondContact CE1-O 3.36Å; H133-R442 PolarHBondContact CD2-NH1 3.19Å; H133-R442 WeakPolarHBondContact NE2-CD 3.28Å; H133-R442 PolarHBondContact NE2-NH1 3.02Å
134K91.3Very high90.4Very high133 Ų13344 Ų4458%0.57822%0.223SC*.Hα-helixtrans-60-43.5180-72.7175.4-176.81800111.9D130 S131 K138D130-K134 WeakPolarHBondContact O-CG 3.13Å; D130-K134 PolarHBondContact O-N 3.19Å; D130-K134 VanDerWaalsContact O-N 3.12Å; S131-K134 PolarHBondContact O-N 2.86Å; S131-K134 VanDerWaalsContact O-N 3.14Å; K134-K138 PolarHBondContact O-N 3.02Å
135Q88.9Confident90.5Very high91 Ų9146.2 Ų46.243%0.42523%0.234SC..Hα-helixtrans-63.8-52.8179.1-170.5178.416.800111S131 H133 K137 K138 V139 E285S131-Q135 WeakPolarHBondContact O-CB 3.25Å; S131-Q135 PolarHBondContact O-N 3.42Å; H133-Q135 VanDerWaalsContact C-N 3.33Å; H133-Q135 PolarHBondContact O-N 2.69Å; Q135-K137 VanDerWaalsContact C-N 3.31Å; Q135-K137 PolarHBondContact O-N 2.82Å; Q135-K138 WeakPolarHBondContact O-CB 3.25Å; Q135-K138 PolarHBondContact O-N 3.46Å; Q135-K138 VanDerWaalsContact O-N 3.13Å; Q135-V139 PolarHBondContact O-N 3.2Å; Q135-E285 WeakPolarHBondContact CG-OE1 3.43Å; Q135-E285 VanDerWaalsContact NE2-CG 3.32Å; Q135-E285 PolarHBondContact NE2-OE1 2.92Å
136R90.3Very high90.5Very high32 Ų3250.8 Ų50.812%0.12125%0.251CS..Hα-helixtrans-58.4-43.3177.7-175.162.961.2134.78.6112L125 L128 S132 H133 K138 V139 I140 A291 S295L125-R136 HydrophobicContact CB-CG 4.27Å; L125-R136 HydrophobicContact CD1-CB 3.73Å; L125-R136 HydrophobicContact CD1-CG 3.76Å; L128-R136 HydrophobicContact CD1-CB 3.62Å; L128-R136 HydrophobicContact CD1-CG 3.87Å; S132-R136 WeakPolarHBondContact O-CB 3.4Å; S132-R136 PolarHBondContact O-N 2.68Å; H133-R136 PolarHBondContact O-N 2.72Å; R136-K138 VanDerWaalsContact C-N 3.31Å; R136-K138 PolarHBondContact O-N 2.72Å; R136-V139 PolarHBondContact O-N 3.43Å; R136-I140 HydrophobicContact CG-CD1 3.77Å; R136-I140 WeakPolarHBondContact O-CG1 3.21Å; R136-I140 PolarHBondContact O-N 2.84Å; R136-A291 PolarHBondContact NH1-O 3.45Å; R136-A291 VanDerWaalsContact NH2-CB 3.31Å; R136-S295 PolarHBondContact NH1-OG 3Å
137K92.3Very high90.6Very high30 Ų3055.7 Ų55.713%0.1327%0.271CS..Hα-helixtrans-58.8-43.7177.5-175.5162.7172.3163.10111.3L125 H133 Q135 V139 I140 M141 P441 S443 V445L125-K137 HydrophobicContact CD1-CB 3.81Å; L125-K137 HydrophobicContact CD2-CB 4.38Å; H133-K137 VanDerWaalsContact O-CB 3.23Å; H133-K137 WeakPolarHBondContact O-CB 3.46Å; H133-K137 PolarHBondContact O-N 3.4Å; Q135-K137 VanDerWaalsContact C-N 3.31Å; Q135-K137 PolarHBondContact O-N 2.82Å; K137-V139 VanDerWaalsContact C-N 3.31Å; K137-V139 PolarHBondContact O-N 2.86Å; K137-I140 PolarHBondContact O-N 3.19Å; K137-M141 HydrophobicContact CG-CG 4.13Å; K137-M141 WeakPolarHBondContact O-CB 3.27Å; K137-M141 WeakPolarHBondContact O-CG 3.23Å; K137-M141 PolarHBondContact O-N 3.48Å; K137-P441 PolarHBondContact NZ-O 3.27Å; K137-S443 PolarHBondContact NZ-O 3.09Å; K137-S443 PolarHBondContact NZ-OG 2.91Å; K137-V445 HydrophobicContact CD-CG1 4.13Å; K137-V445 HydrophobicContact CG-CG1 3.79Å
138K89.5Confident90.8Very high110 Ų11055.3 Ų55.348%0.47827%0.27SS..Hα-helixtrans-61.1-40.4-178.9-175.2177.1176.8-175.40112K134 Q135 R136K134-K138 PolarHBondContact O-N 3.02Å; Q135-K138 WeakPolarHBondContact O-CB 3.25Å; Q135-K138 PolarHBondContact O-N 3.46Å; Q135-K138 VanDerWaalsContact O-N 3.13Å; R136-K138 VanDerWaalsContact C-N 3.31Å; R136-K138 PolarHBondContact O-N 2.72Å
139V88.6Confident90.9Very high3 Ų354.3 Ų54.32%0.01827%0.265CS..Hα-helixtrans-67.4-50.4176.1-178.60000110.4Q135 R136 K137 M141 Q142 L276 L287Q135-V139 PolarHBondContact O-N 3.2Å; R136-V139 PolarHBondContact O-N 3.43Å; K137-V139 VanDerWaalsContact C-N 3.31Å; K137-V139 PolarHBondContact O-N 2.86Å; V139-M141 VanDerWaalsContact C-N 3.29Å; V139-M141 PolarHBondContact O-N 3.33Å; V139-Q142 WeakPolarHBondContact O-CB 3.5Å; V139-Q142 PolarHBondContact O-N 3.29Å; V139-Q142 VanDerWaalsContact O-N 3.11Å; V139-L276 HydrophobicContact CG1-CD2 3.87Å; V139-L287 HydrophobicContact CG1-CD1 4.46Å
140I90.4Very high91Very high1 Ų156.2 Ų56.21%0.00527%0.274CS..Hα-helixtrans-60.1-37179.9-68.3168.6000112.8L125 R136 K137 Q142 A143 F144 L276 L299 V445L125-I140 HydrophobicContact CB-CD1 4.1Å; L125-I140 HydrophobicContact CD2-CD1 4.05Å; L125-I140 HydrophobicContact CG-CD1 4.47Å; R136-I140 HydrophobicContact CG-CD1 3.77Å; R136-I140 WeakPolarHBondContact O-CG1 3.21Å; R136-I140 PolarHBondContact O-N 2.84Å; K137-I140 PolarHBondContact O-N 3.19Å; I140-Q142 PolarHBondContact O-N 3.2Å; I140-A143 WeakPolarHBondContact O-CB 3.28Å; I140-A143 PolarHBondContact O-N 3.46Å; I140-A143 VanDerWaalsContact O-N 3.16Å; I140-F144 HydrophobicContact CG2-CD2 4.41Å; I140-F144 HydrophobicContact CG2-CE2 3.9Å; I140-F144 WeakPolarHBondContact O-CD2 3.49Å; I140-L276 HydrophobicContact CB-CD2 4.26Å; I140-L276 HydrophobicContact CG1-CD2 3.76Å; I140-L299 HydrophobicContact CG2-CD2 3.89Å; I140-V445 HydrophobicContact CG2-CB 4.22Å; I140-V445 HydrophobicContact CG2-CG2 3.91Å
141M91.2Very high91.1Very high73 Ų7353.8 Ų53.836%0.3626%0.263SS..G310 helixtrans-62.2-21.7179-77.2-65.8-51.500113.8K137 V139 A143 F144 V445K137-M141 HydrophobicContact CG-CG 4.13Å; K137-M141 WeakPolarHBondContact O-CB 3.27Å; K137-M141 WeakPolarHBondContact O-CG 3.23Å; K137-M141 PolarHBondContact O-N 3.48Å; V139-M141 VanDerWaalsContact C-N 3.29Å; V139-M141 PolarHBondContact O-N 3.33Å; M141-A143 VanDerWaalsContact C-N 3.29Å; M141-A143 PolarHBondContact O-N 2.9Å; M141-F144 PolarHBondContact O-N 3.45Å; M141-V445 HydrophobicContact CG-CG1 4.25Å; M141-V445 VanDerWaalsContact SD-CA 3.55Å; M141-V445 HydrophobicContact SD-CB 3.68Å; M141-V445 HydrophobicContact SD-CG1 3.81Å
142Q88.8Confident91.3Very high67 Ų6749.7 Ų49.731%0.31323%0.234SC..G310 helixtrans-67.9-32177-60.6-50.9-52.200112.2V139 I140 F144 N145 H279V139-Q142 WeakPolarHBondContact O-CB 3.5Å; V139-Q142 PolarHBondContact O-N 3.29Å; V139-Q142 VanDerWaalsContact O-N 3.11Å; I140-Q142 PolarHBondContact O-N 3.2Å; Q142-F144 PolarHBondContact O-N 3.4Å; Q142-N145 PolarHBondContact O-N 3.15Å; Q142-N145 PolarHBondContact O-ND2 3.04Å; Q142-H279 WeakPolarHBondContact CB-CD2 3.26Å
143A90.1Very high91.5Very high0 Ų047.7 Ų47.70%022%0.219CC..G310 helixtrans-67.6-4.2174.700000113.9I140 M141 Y152 A272 L275I140-A143 WeakPolarHBondContact O-CB 3.28Å; I140-A143 PolarHBondContact O-N 3.46Å; I140-A143 VanDerWaalsContact O-N 3.16Å; M141-A143 VanDerWaalsContact C-N 3.29Å; M141-A143 PolarHBondContact O-N 2.9Å; A143-Y152 WeakPolarHBondContact O-CE2 3.36Å; A143-Y152 PolarHBondContact O-OH 3.09Å; A143-A272 HydrophobicContact CB-CB 3.62Å; A143-L275 HydrophobicContact CB-CB 4.4Å; A143-L275 HydrophobicContact CB-CD1 4.46Å
144F92Very high91.5Very high14 Ų1451.1 Ų51.16%0.06124%0.242CC..G310 helixtrans-130.423.3-179.1-54.2-64000112.2I140 M141 Q142 L193 L299 V445 F449I140-F144 HydrophobicContact CG2-CD2 4.41Å; I140-F144 HydrophobicContact CG2-CE2 3.9Å; I140-F144 WeakPolarHBondContact O-CD2 3.49Å; M141-F144 PolarHBondContact O-N 3.45Å; Q142-F144 PolarHBondContact O-N 3.4Å; F144-L193 HydrophobicContact CE1-CD2 3.84Å; F144-L193 HydrophobicContact CZ-CD2 3.97Å; F144-L299 HydrophobicContact CE2-CD2 3.79Å; F144-L299 HydrophobicContact CZ-CD2 3.75Å; F144-V445 HydrophobicContact CE2-CG2 4.4Å; F144-F449 HydrophobicContact CD1-CB 3.7Å; F144-F449 HydrophobicContact CD1-CG 4.18Å; F144-F449 HydrophobicContact CE1-CB 4.1Å; F144-F449 HydrophobicContact CE1-CG 4.16Å
145N91.4Very high91.5Very high47 Ų4746.1 Ų46.125%0.25122%0.223SC..SBendtrans-71.5172.7170.268.920.6000111.1Q142 E147 A148 L149Q142-N145 PolarHBondContact O-N 3.15Å; Q142-N145 PolarHBondContact O-ND2 3.04Å; N145-E147 VanDerWaalsContact C-N 3.29Å; N145-E147 PolarHBondContact O-N 3.45Å; N145-E147 PolarHBondContact OD1-N 3.23Å; N145-E147 PolarHBondContact OD1-OE2 3.03Å; N145-A148 PolarHBondContact O-N 3.31Å; N145-A148 WeakPolarHBondContact OD1-CB 3.35Å; N145-A148 PolarHBondContact OD1-N 3.34Å; N145-L149 VanDerWaalsContact O-CG 3.24Å; N145-L149 WeakPolarHBondContact O-CG 3.41Å; N145-L149 PolarHBondContact O-N 3.42Å
146R92.1Very high91.8Very high109 Ų10941.8 Ų41.841%0.41120%0.202SC..Hα-helixtrans-61.5-41.5-173.6-178.4-176.8-176.979.7-2111.5L149 Q150 E353R146-L149 PolarHBondContact O-N 2.69Å; R146-Q150 PolarHBondContact O-N 3.4Å; R146-E353 IonicContact CZ-OE1 3.38Å; R146-E353 IonicContact CZ-OE2 2.74Å; R146-E353 IonicContact NH1-OE1 2.66Å; R146-E353 PolarHBondContact NH1-OE1 2.97Å; R146-E353 IonicContact NH1-OE2 3.94Å; R146-E353 IonicContact NH2-OE1 3.61Å; R146-E353 IonicContact NH2-OE2 3.33Å; R146-E353 PolarHBondContact NH2-OE2 3.26Å
147E91.1Very high92Very high124 Ų12441.3 Ų41.358%0.57921%0.205SC*.Hα-helixtrans-64.3-47.2-176.9-6269.7-151.600110.6N145 Q150 C151N145-E147 VanDerWaalsContact C-N 3.29Å; N145-E147 PolarHBondContact O-N 3.45Å; N145-E147 PolarHBondContact OD1-N 3.23Å; N145-E147 PolarHBondContact OD1-OE2 3.03Å; E147-Q150 PolarHBondContact O-N 2.76Å; E147-C151 PolarHBondContact O-N 2.94Å
148A92.2Very high92Very high7 Ų744.8 Ų44.86%0.05822%0.222CC..Hα-helixtrans-61.5-45.1174.200000111.6N145 Q150 C151 Y152 L275N145-A148 PolarHBondContact O-N 3.31Å; N145-A148 WeakPolarHBondContact OD1-CB 3.35Å; N145-A148 PolarHBondContact OD1-N 3.34Å; A148-Q150 VanDerWaalsContact C-N 3.29Å; A148-Q150 PolarHBondContact O-N 3.4Å; A148-C151 VanDerWaalsContact O-CB 3.3Å; A148-C151 WeakPolarHBondContact O-CB 3.06Å; A148-C151 PolarHBondContact O-N 2.91Å; A148-C151 VanDerWaalsContact O-N 3.1Å; A148-Y152 HydrophobicContact CB-CE2 4.13Å; A148-Y152 VanDerWaalsContact O-CD1 3.23Å; A148-Y152 WeakPolarHBondContact O-CD1 3.46Å; A148-Y152 WeakPolarHBondContact O-CD2 3.43Å; A148-Y152 PolarHBondContact O-N 3.47Å; A148-Y152 VanDerWaalsContact O-N 3.12Å; A148-L275 HydrophobicContact CB-CD1 3.69Å
149L94.5Very high92.3Very high7 Ų740.2 Ų40.24%0.03720%0.202CC..Hα-helixtrans-60.8-37.8178-69177.5000112.4N145 R146 C151 Y152 V153 M349 E448 F449 V452N145-L149 VanDerWaalsContact O-CG 3.24Å; N145-L149 WeakPolarHBondContact O-CG 3.41Å; N145-L149 PolarHBondContact O-N 3.42Å; R146-L149 PolarHBondContact O-N 2.69Å; L149-C151 VanDerWaalsContact C-N 3.28Å; L149-C151 PolarHBondContact O-N 3.03Å; L149-Y152 HydrophobicContact CD2-CD2 4.1Å; L149-Y152 WeakPolarHBondContact O-CB 3.03Å; L149-Y152 PolarHBondContact O-N 2.65Å; L149-V153 WeakPolarHBondContact O-CG2 3.48Å; L149-V153 PolarHBondContact O-N 2.97Å; L149-M349 HydrophobicContact CB-CE 4.28Å; L149-M349 HydrophobicContact CB-SD 4.2Å; L149-E448 HydrophobicContact CD1-CB 3.84Å; L149-F449 HydrophobicContact CD2-CB 3.79Å; L149-F449 HydrophobicContact CD2-CD2 4.02Å; L149-F449 HydrophobicContact CD2-CG 4.43Å; L149-V452 HydrophobicContact CD1-CG2 4.38Å
150Q92.9Very high92.6Very high110 Ų11040 Ų4051%0.51420%0.201SC..Hα-helixtrans-61.8-38.4176-176.7168.1-6.100112R146 E147 A148 Y152 M349R146-Q150 PolarHBondContact O-N 3.4Å; E147-Q150 PolarHBondContact O-N 2.76Å; A148-Q150 VanDerWaalsContact C-N 3.29Å; A148-Q150 PolarHBondContact O-N 3.4Å; Q150-Y152 VanDerWaalsContact C-N 3.27Å; Q150-Y152 PolarHBondContact O-N 2.86Å; Q150-M349 HydrophobicContact CB-CG 3.91Å; Q150-M349 HydrophobicContact CG-CG 4.35Å
151C91.8Very high92.8Very high30 Ų3040.9 Ų40.920%0.20321%0.21CC..Hα-helixtrans-65.9-28.2172.7-88.50000113.7E147 A148 L149 P154 C269E147-C151 PolarHBondContact O-N 2.94Å; A148-C151 VanDerWaalsContact O-CB 3.3Å; A148-C151 WeakPolarHBondContact O-CB 3.06Å; A148-C151 PolarHBondContact O-N 2.91Å; A148-C151 VanDerWaalsContact O-N 3.1Å; L149-C151 VanDerWaalsContact C-N 3.28Å; L149-C151 PolarHBondContact O-N 3.03Å; C151-P154 WeakPolarHBondContact O-CD 3.46Å; C151-P154 WeakPolarHBondContact O-CG 3.43Å; C151-C269 WeakPolarHBondContact CA-SG 3.5Å; C151-C269 HydrophobicContact CB-CB 3.49Å; C151-C269 VanDerWaalsContact CB-CB 3.49Å; C151-C269 WeakPolarHBondContact CB-SG 3.34Å; C151-C269 WeakPolarHBondContact SG-CA 3.36Å; C151-C269 WeakPolarHBondContact SG-CB 3.39Å; C151-C269 CovalentContact SG-SG 2.05Å; C151-C269 PolarHBondContact SG-SG 3.27Å
152Y94.6Very high92.9Very high6 Ų639.9 Ų39.92%0.02421%0.21CC..Hα-helixtrans-81.2-26.4-177.5-60.8-14.4000113.4A143 A148 L149 Q150 V155 I156 I192 K270 A272 F449A143-Y152 WeakPolarHBondContact O-CE2 3.36Å; A143-Y152 PolarHBondContact O-OH 3.09Å; A148-Y152 HydrophobicContact CB-CE2 4.13Å; A148-Y152 VanDerWaalsContact O-CD1 3.23Å; A148-Y152 WeakPolarHBondContact O-CD1 3.46Å; A148-Y152 WeakPolarHBondContact O-CD2 3.43Å; A148-Y152 PolarHBondContact O-N 3.47Å; A148-Y152 VanDerWaalsContact O-N 3.12Å; L149-Y152 HydrophobicContact CD2-CD2 4.1Å; L149-Y152 WeakPolarHBondContact O-CB 3.03Å; L149-Y152 PolarHBondContact O-N 2.65Å; Q150-Y152 VanDerWaalsContact C-N 3.27Å; Q150-Y152 PolarHBondContact O-N 2.86Å; Y152-V155 PolarHBondContact O-N 2.97Å; Y152-I156 VanDerWaalsContact O-CG1 3.29Å; Y152-I156 WeakPolarHBondContact O-CG1 3.35Å; Y152-I156 PolarHBondContact O-N 3.37Å; Y152-I192 HydrophobicContact CD1-CG2 3.62Å; Y152-I192 HydrophobicContact CD2-CG2 3.44Å; Y152-I192 VanDerWaalsContact CD2-CG2 3.44Å; Y152-I192 HydrophobicContact CE1-CG2 3.79Å; Y152-I192 HydrophobicContact CE2-CG2 3.61Å; Y152-I192 HydrophobicContact CG-CG2 3.46Å; Y152-I192 VanDerWaalsContact CG-CG2 3.46Å; Y152-K270 WeakPolarHBondContact CE1-O 3.49Å; Y152-A272 PolarHBondContact OH-N 2.97Å; Y152-F449 AromaticContact CD2-CD2 3.99Å; Y152-F449 HydrophobicContact CD2-CD2 3.99Å; Y152-F449 HydrophobicContact CD2-CE2 4.17Å
153V94.7Very high93.2Very high2 Ų236.7 Ų36.71%0.01220%0.195CC..Hα-helixtrans-49.6-53.4-179.2178.50000113.8L149 V155 I156 A157 L347 M349 L352 V452 I456L149-V153 WeakPolarHBondContact O-CG2 3.48Å; L149-V153 PolarHBondContact O-N 2.97Å; V153-V155 VanDerWaalsContact C-N 3.35Å; V153-V155 PolarHBondContact O-N 2.93Å; V153-I156 PolarHBondContact O-N 3.3Å; V153-A157 WeakPolarHBondContact O-CB 3.39Å; V153-A157 PolarHBondContact O-N 3.19Å; V153-L347 HydrophobicContact CG1-CB 3.88Å; V153-L347 WeakPolarHBondContact CG1-O 2.87Å; V153-M349 HydrophobicContact CG2-CG 4.04Å; V153-M349 HydrophobicContact CG2-SD 3.89Å; V153-L352 HydrophobicContact CG1-CD1 4.24Å; V153-L352 HydrophobicContact CG2-CD1 3.96Å; V153-V452 HydrophobicContact CG2-CG1 4.15Å; V153-I456 HydrophobicContact CB-CD1 4.18Å; V153-I456 HydrophobicContact CG1-CD1 3.85Å; V153-I456 HydrophobicContact CG1-CG1 4.49Å; V153-I456 HydrophobicContact CG2-CD1 4.21Å
154P92Very high93.4Very high77 Ų7736.8 Ų36.850%0.520%0.196SC..Hα-helixtrans-63.1-39.4-178.223.5-34.4000112.8C151 A157 E158C151-P154 WeakPolarHBondContact O-CD 3.46Å; C151-P154 WeakPolarHBondContact O-CG 3.43Å; P154-A157 PolarHBondContact O-N 3.45Å; P154-E158 WeakPolarHBondContact O-CB 3.47Å; P154-E158 PolarHBondContact O-N 3.02Å
155V92.5Very high93.5Very high29 Ų2942.9 Ų42.918%0.17622%0.224CC..Hα-helixtrans-64.7-43.3178.9-178.50000110.9Y152 V153 E158 E159 R191 I192Y152-V155 PolarHBondContact O-N 2.97Å; V153-V155 VanDerWaalsContact C-N 3.35Å; V153-V155 PolarHBondContact O-N 2.93Å; V155-E158 PolarHBondContact O-N 3.28Å; V155-E159 WeakPolarHBondContact O-CG 3.33Å; V155-E159 PolarHBondContact O-N 2.85Å; V155-E159 VanDerWaalsContact O-N 3.08Å; V155-R191 HydrophobicContact CG1-CB 3.88Å; V155-I192 HydrophobicContact CB-CD1 4.49Å; V155-I192 HydrophobicContact CB-CG1 4.24Å; V155-I192 HydrophobicContact CG1-CD1 4.34Å; V155-I192 HydrophobicContact CG1-CG1 3.85Å
156I95.5Very high93.6Very high0 Ų045.4 Ų45.40%024%0.235CC..Hα-helixtrans-63-46.8176.1-61166.4000110Y152 V153 E158 E159 V160 I188 I192 F449 V452 L453 I456Y152-I156 VanDerWaalsContact O-CG1 3.29Å; Y152-I156 WeakPolarHBondContact O-CG1 3.35Å; Y152-I156 PolarHBondContact O-N 3.37Å; V153-I156 PolarHBondContact O-N 3.3Å; I156-E158 VanDerWaalsContact C-N 3.33Å; I156-E158 PolarHBondContact O-N 3.18Å; I156-E159 PolarHBondContact O-N 2.58Å; I156-V160 HydrophobicContact CG2-CG2 4.11Å; I156-V160 WeakPolarHBondContact O-CB 3.3Å; I156-V160 WeakPolarHBondContact O-CG2 3.3Å; I156-V160 PolarHBondContact O-N 3.35Å; I156-I188 HydrophobicContact CG1-CG2 4.21Å; I156-I188 HydrophobicContact CG2-CD1 4.38Å; I156-I192 HydrophobicContact CD1-CD1 3.93Å; I156-I192 HydrophobicContact CG1-CD1 3.29Å; I156-F449 HydrophobicContact CD1-CE2 4Å; I156-V452 HydrophobicContact CD1-CG1 4.37Å; I156-L453 HydrophobicContact CD1-CB 4.15Å; I156-L453 HydrophobicContact CG2-CG 4.21Å; I156-I456 HydrophobicContact CB-CD1 3.84Å; I156-I456 HydrophobicContact CB-CG2 4.3Å; I156-I456 HydrophobicContact CD1-CD1 3.89Å; I156-I456 HydrophobicContact CG1-CD1 4.45Å; I156-I456 HydrophobicContact CG2-CB 3.89Å; I156-I456 HydrophobicContact CG2-CD1 3.88Å; I156-I456 HydrophobicContact CG2-CG2 3.68Å
157A94.3Very high93.8Very high21 Ų2140.4 Ų40.417%0.17422%0.216CC..Hα-helixtrans-62-41.5-178.500000111.9V153 P154 G161 I456V153-A157 WeakPolarHBondContact O-CB 3.39Å; V153-A157 PolarHBondContact O-N 3.19Å; P154-A157 PolarHBondContact O-N 3.45Å; A157-G161 PolarHBondContact O-N 3.25Å; A157-I456 HydrophobicContact CB-CG2 4.03Å
158E92.9Very high94Very high104 Ų10435.5 Ų35.549%0.48619%0.193SC..Hα-helixtrans-61.6-50176.3-178.5-175.1-155.200112.3P154 V155 I156 V160 G161 S162 R191P154-E158 WeakPolarHBondContact O-CB 3.47Å; P154-E158 PolarHBondContact O-N 3.02Å; V155-E158 PolarHBondContact O-N 3.28Å; I156-E158 VanDerWaalsContact C-N 3.33Å; I156-E158 PolarHBondContact O-N 3.18Å; E158-V160 PolarHBondContact O-N 2.82Å; E158-G161 PolarHBondContact O-N 2.93Å; E158-S162 WeakPolarHBondContact O-CB 3.32Å; E158-S162 PolarHBondContact O-N 3.43Å; E158-S162 PolarHBondContact O-OG 2.89Å; E158-R191 IonicContact OE2-CZ 3.39Å; E158-R191 VanDerWaalsContact OE2-CZ 3.29Å; E158-R191 IonicContact OE2-NH1 2.93Å; E158-R191 PolarHBondContact OE2-NH1 3.44Å; E158-R191 IonicContact OE2-NH2 3.11Å; E158-R191 PolarHBondContact OE2-NH2 3.34Å
159E93.9Very high94Very high13 Ų1339.4 Ų39.46%0.06122%0.22CC..Hα-helixtrans-63.3-42.2179.6-77.9-59.8142.700112.2V155 I156 C163 L184 R187 I188 R191V155-E159 WeakPolarHBondContact O-CG 3.33Å; V155-E159 PolarHBondContact O-N 2.85Å; V155-E159 VanDerWaalsContact O-N 3.08Å; I156-E159 PolarHBondContact O-N 2.58Å; E159-C163 VanDerWaalsContact O-CB 3.28Å; E159-C163 WeakPolarHBondContact O-CB 3.36Å; E159-C163 PolarHBondContact O-N 3.27Å; E159-C163 VanDerWaalsContact O-N 3.08Å; E159-L184 HydrophobicContact CB-CD1 3.97Å; E159-L184 WeakPolarHBondContact O-CD1 3.38Å; E159-R187 WeakPolarHBondContact OE2-CB 3.3Å; E159-R187 IonicContact OE2-NE 2.65Å; E159-R187 PolarHBondContact OE2-NE 3.35Å; E159-I188 HydrophobicContact CB-CD1 4.22Å; E159-I188 HydrophobicContact CB-CG1 3.58Å; E159-I188 HydrophobicContact CG-CG1 3.93Å; E159-R191 WeakPolarHBondContact OE1-CD 3.29Å; E159-R191 IonicContact OE1-CZ 2.79Å; E159-R191 IonicContact OE1-NE 3.45Å; E159-R191 IonicContact OE1-NH1 3.61Å; E159-R191 PolarHBondContact OE1-NH1 3.44Å
160V96.5Very high93.9Very high0 Ų040.7 Ų40.70%023%0.229CC..Hα-helixtrans-65.4-48.9177175.50000110I156 E158 S162 C163 L164 L184 I188 F457 E460I156-V160 HydrophobicContact CG2-CG2 4.11Å; I156-V160 WeakPolarHBondContact O-CB 3.3Å; I156-V160 WeakPolarHBondContact O-CG2 3.3Å; I156-V160 PolarHBondContact O-N 3.35Å; E158-V160 PolarHBondContact O-N 2.82Å; V160-S162 PolarHBondContact O-N 3.1Å; V160-C163 WeakPolarHBondContact O-CB 3.42Å; V160-C163 PolarHBondContact O-N 3.39Å; V160-L164 HydrophobicContact CG1-CD1 3.96Å; V160-L164 HydrophobicContact CG1-CG 4.19Å; V160-L164 WeakPolarHBondContact O-CG 3.25Å; V160-L164 PolarHBondContact O-N 3.35Å; V160-L184 HydrophobicContact CG2-CD2 4.28Å; V160-I188 HydrophobicContact CG2-CD1 4.13Å; V160-F457 HydrophobicContact CG1-CD2 3.89Å; V160-F457 HydrophobicContact CG2-CD2 4Å; V160-E460 HydrophobicContact CB-CB 4.47Å; V160-E460 HydrophobicContact CB-CG 4.45Å; V160-E460 HydrophobicContact CG1-CB 3.55Å; V160-E460 HydrophobicContact CG1-CG 4.04Å
161G94.3Very high93.5Very high18 Ų1836.9 Ų36.919%0.18622%0.22CC..Hα-helixtrans-55.9-51.317900000112.1A157 E158 C163 L164 E165A157-G161 PolarHBondContact O-N 3.25Å; E158-G161 PolarHBondContact O-N 2.93Å; G161-C163 VanDerWaalsContact C-N 3.28Å; G161-C163 PolarHBondContact O-N 2.99Å; G161-L164 PolarHBondContact O-N 2.83Å; G161-L164 VanDerWaalsContact O-N 3.1Å; G161-E165 PolarHBondContact O-N 3.36Å
162S92.7Very high93Very high52 Ų5243.2 Ų43.236%0.36425%0.246SC..Hα-helixtrans-57.5-41177.6-57.50000112.2E158 V160 Q166E158-S162 WeakPolarHBondContact O-CB 3.32Å; E158-S162 PolarHBondContact O-N 3.43Å; E158-S162 PolarHBondContact O-OG 2.89Å; V160-S162 PolarHBondContact O-N 3.1Å; S162-Q166 WeakPolarHBondContact O-CG 3.31Å; S162-Q166 PolarHBondContact O-N 2.99Å
163C94.9Very high92.7Very high0 Ų052.9 Ų52.90%028%0.283CS..Hα-helixtrans-67.3-40.3177.3-169.20000112.5E159 V160 G161 Q166 W167 L184E159-C163 VanDerWaalsContact O-CB 3.28Å; E159-C163 WeakPolarHBondContact O-CB 3.36Å; E159-C163 PolarHBondContact O-N 3.27Å; E159-C163 VanDerWaalsContact O-N 3.08Å; V160-C163 WeakPolarHBondContact O-CB 3.42Å; V160-C163 PolarHBondContact O-N 3.39Å; G161-C163 VanDerWaalsContact C-N 3.28Å; G161-C163 PolarHBondContact O-N 2.99Å; C163-Q166 WeakPolarHBondContact O-CB 3.24Å; C163-Q166 PolarHBondContact O-N 3.23Å; C163-W167 VanDerWaalsContact O-CG 3.32Å; C163-W167 PolarHBondContact O-N 3.2Å; C163-W167 VanDerWaalsContact SG-CZ2 3.59Å; C163-W167 PolarHBondContact SG-NE1 3.32Å; C163-L184 HydrophobicContact CB-CD1 3.86Å; C163-L184 HydrophobicContact CB-CD2 4.09Å; C163-L184 HydrophobicContact CB-CG 4.39Å
164L95.3Very high92.6Very high3 Ų353.4 Ų53.42%0.01629%0.289CS..Hα-helixtrans-67.8-37.5178.8-67-178.9000111.7V160 G161 Q166 W167 L168 E460 L461V160-L164 HydrophobicContact CG1-CD1 3.96Å; V160-L164 HydrophobicContact CG1-CG 4.19Å; V160-L164 WeakPolarHBondContact O-CG 3.25Å; V160-L164 PolarHBondContact O-N 3.35Å; G161-L164 PolarHBondContact O-N 2.83Å; G161-L164 VanDerWaalsContact O-N 3.1Å; L164-Q166 VanDerWaalsContact C-N 3.31Å; L164-Q166 PolarHBondContact O-N 3.16Å; L164-W167 HydrophobicContact CD2-CD2 4.35Å; L164-W167 HydrophobicContact CD2-CE3 3.61Å; L164-W167 HydrophobicContact CD2-CZ3 3.76Å; L164-W167 PolarHBondContact O-N 3.01Å; L164-L168 WeakPolarHBondContact O-CB 3.49Å; L164-L168 WeakPolarHBondContact O-CD1 3.33Å; L164-L168 WeakPolarHBondContact O-CG 3.33Å; L164-L168 PolarHBondContact O-N 3.32Å; L164-E460 HydrophobicContact CD1-CB 3.92Å; L164-L461 HydrophobicContact CD1-CD2 4.4Å; L164-L461 HydrophobicContact CD2-CD2 3.56Å; L164-L461 HydrophobicContact CD2-CG 4.32Å
165E93.8Very high92.8Very high141 Ų14150.9 Ų50.966%0.65927%0.271SS*.Hα-helixtrans-58.8-43.5172.7-71.5-178.3177.100111.7G161 W167 L168 S169G161-E165 PolarHBondContact O-N 3.36Å; E165-W167 PolarHBondContact O-N 2.94Å; E165-L168 PolarHBondContact O-N 3.48Å; E165-S169 PolarHBondContact O-N 3.37Å
166Q93.6Very high93Very high100 Ų10053.3 Ų53.347%0.46728%0.282SS..Hα-helixtrans-60.9-44.4174.4-68.7172.6-300111.5S162 C163 L164 L168 S169 C170S162-Q166 WeakPolarHBondContact O-CG 3.31Å; S162-Q166 PolarHBondContact O-N 2.99Å; C163-Q166 WeakPolarHBondContact O-CB 3.24Å; C163-Q166 PolarHBondContact O-N 3.23Å; L164-Q166 VanDerWaalsContact C-N 3.31Å; L164-Q166 PolarHBondContact O-N 3.16Å; Q166-L168 PolarHBondContact O-N 3.19Å; Q166-S169 WeakPolarHBondContact O-CB 3.48Å; Q166-S169 PolarHBondContact O-N 3.33Å; Q166-S169 PolarHBondContact O-OG 3.05Å; Q166-C170 PolarHBondContact O-N 3.02Å
167W95.6Very high93.1Very high4 Ų453.3 Ų53.32%0.01528%0.282CS..Hα-helixtrans-64.6-39.2178.5-66.23.9000112.7C163 L164 E165 S169 C170 L175 E180 V181 I315 F457 L461 F492C163-W167 VanDerWaalsContact O-CG 3.32Å; C163-W167 PolarHBondContact O-N 3.2Å; C163-W167 VanDerWaalsContact SG-CZ2 3.59Å; C163-W167 PolarHBondContact SG-NE1 3.32Å; L164-W167 HydrophobicContact CD2-CD2 4.35Å; L164-W167 HydrophobicContact CD2-CE3 3.61Å; L164-W167 HydrophobicContact CD2-CZ3 3.76Å; L164-W167 PolarHBondContact O-N 3.01Å; E165-W167 PolarHBondContact O-N 2.94Å; W167-S169 VanDerWaalsContact C-N 3.27Å; W167-S169 PolarHBondContact O-N 3.46Å; W167-C170 VanDerWaalsContact O-CB 3.31Å; W167-C170 WeakPolarHBondContact O-CB 3.44Å; W167-C170 PolarHBondContact O-N 3.25Å; W167-L175 HydrophobicContact CB-CD2 3.68Å; W167-L175 HydrophobicContact CD2-CD1 4.1Å; W167-L175 HydrophobicContact CD2-CD2 4.35Å; W167-L175 HydrophobicContact CG-CD1 4.14Å; W167-L175 HydrophobicContact CG-CD2 3.78Å; W167-E180 HydrophobicContact CZ2-CB 3.75Å; W167-V181 HydrophobicContact CH2-CG2 3.56Å; W167-V181 HydrophobicContact CZ2-CG2 4Å; W167-I315 HydrophobicContact CH2-CD1 4.05Å; W167-I315 HydrophobicContact CZ3-CD1 3.85Å; W167-F457 HydrophobicContact CH2-CZ 4.43Å; W167-L461 HydrophobicContact CZ3-CD2 4.46Å; W167-F492 HydrophobicContact CB-CD2 4.45Å; W167-F492 HydrophobicContact CB-CG 4.42Å; W167-F492 HydrophobicContact CE3-CD1 4.14Å; W167-F492 HydrophobicContact CE3-CD2 4.32Å; W167-F492 AromaticContact CE3-CE1 3.71Å; W167-F492 HydrophobicContact CE3-CE1 3.71Å; W167-F492 AromaticContact CE3-CE2 3.89Å; W167-F492 HydrophobicContact CE3-CE2 3.89Å; W167-F492 HydrophobicContact CE3-CG 4.44Å; W167-F492 AromaticContact CE3-CZ 3.57Å; W167-F492 HydrophobicContact CE3-CZ 3.57Å; W167-F492 AromaticContact CZ3-CE1 3.96Å; W167-F492 HydrophobicContact CZ3-CE1 3.96Å; W167-F492 HydrophobicContact CZ3-CE2 4.39Å; W167-F492 AromaticContact CZ3-CZ 3.73Å; W167-F492 HydrophobicContact CZ3-CZ 3.73Å
168L94.7Very high93.3Very high21 Ų2153.2 Ų53.211%0.1128%0.278CS..Hα-helixtrans-64.7-33.2176.1-71.9162.5000111.6L164 E165 Q166 C170 G171 F492L164-L168 WeakPolarHBondContact O-CB 3.49Å; L164-L168 WeakPolarHBondContact O-CD1 3.33Å; L164-L168 WeakPolarHBondContact O-CG 3.33Å; L164-L168 PolarHBondContact O-N 3.32Å; E165-L168 PolarHBondContact O-N 3.48Å; Q166-L168 PolarHBondContact O-N 3.19Å; L168-C170 VanDerWaalsContact C-N 3.25Å; L168-C170 PolarHBondContact O-N 2.92Å; L168-G171 PolarHBondContact O-N 3.49Å; L168-F492 HydrophobicContact CD2-CB 4.26Å
169S93.8Very high93.3Very high89 Ų8950.2 Ų50.262%0.62227%0.267SS*.Hα-helixtrans-69.1-18.7175.484.10000114E165 Q166 W167 G171E165-S169 PolarHBondContact O-N 3.37Å; Q166-S169 WeakPolarHBondContact O-CB 3.48Å; Q166-S169 PolarHBondContact O-N 3.33Å; Q166-S169 PolarHBondContact O-OG 3.05Å; W167-S169 VanDerWaalsContact C-N 3.27Å; W167-S169 PolarHBondContact O-N 3.46Å; S169-G171 PolarHBondContact O-N 3.26Å
170C91.4Very high93.4Very high34 Ų3451.8 Ų51.823%0.2327%0.274CS..THydrogen-bonded Turntrans-65.8-26.8174.4-62.80000112Q166 W167 L168 E172 R173 L175Q166-C170 PolarHBondContact O-N 3.02Å; W167-C170 VanDerWaalsContact O-CB 3.31Å; W167-C170 WeakPolarHBondContact O-CB 3.44Å; W167-C170 PolarHBondContact O-N 3.25Å; L168-C170 VanDerWaalsContact C-N 3.25Å; L168-C170 PolarHBondContact O-N 2.92Å; C170-E172 PolarHBondContact O-N 2.77Å; C170-R173 WeakPolarHBondContact O-CB 3.42Å; C170-R173 PolarHBondContact O-N 2.8Å; C170-R173 PolarHBondContact O-NE 2.98Å; C170-L175 HydrophobicContact CB-CD2 4.41Å
171G84.1Confident93.4Very high30 Ų3051.8 Ų51.831%0.30927%0.274SS..G310 helixtrans53.3-132.1177.400000112.6L168 S169 R173 G174L168-G171 PolarHBondContact O-N 3.49Å; S169-G171 PolarHBondContact O-N 3.26Å; G171-R173 PolarHBondContact O-N 2.97Å; G171-G174 PolarHBondContact O-N 3.05Å
172E82.4Confident93.3Very high164 Ų16452.1 Ų52.177%0.76627%0.271SS*.G310 helixtrans-63.6-22.9-176-65.8-167.7164.500114.6C170 G174 R491C170-E172 PolarHBondContact O-N 2.77Å; E172-G174 PolarHBondContact O-N 2.87Å; E172-R491 PolarHBondContact O-NE 3.23Å; E172-R491 VanDerWaalsContact O-NE 3.1Å; E172-R491 PolarHBondContact O-NH2 3.42Å
173R87.1Confident93.3Very high209 Ų20954.5 Ų54.579%0.78927%0.272SS*.G310 helixtrans-62.3-27.5-179-65.1-176.9-72.5-173-2.1112.4C170 G171C170-R173 WeakPolarHBondContact O-CB 3.42Å; C170-R173 PolarHBondContact O-N 2.8Å; C170-R173 PolarHBondContact O-NE 2.98Å; G171-R173 PolarHBondContact O-N 2.97Å
174G92.4Very high93.2Very high13 Ų1354.5 Ų54.513%0.13427%0.272CS..  trans63-177.1-170.800000112.5G171 E172 A490G171-G174 PolarHBondContact O-N 3.05Å; E172-G174 PolarHBondContact O-N 2.87Å; G174-A490 CarbonylContact C-O 3.37Å; G174-A490 VanDerWaalsContact CA-O 3.22Å; G174-A490 WeakPolarHBondContact CA-O 3.39Å
175L97Very high93.2Very high24 Ų2454.4 Ų54.413%0.12627%0.271CS..EExtended strand (participates in β ladder)trans-149.2166.1177.665.1119.9000111.6W167 C170 V177 E180 P489 A490 F492W167-L175 HydrophobicContact CB-CD2 3.68Å; W167-L175 HydrophobicContact CD2-CD1 4.1Å; W167-L175 HydrophobicContact CD2-CD2 4.35Å; W167-L175 HydrophobicContact CG-CD1 4.14Å; W167-L175 HydrophobicContact CG-CD2 3.78Å; C170-L175 HydrophobicContact CB-CD2 4.41Å; L175-V177 HydrophobicContact CD1-CG2 4.24Å; L175-E180 HydrophobicContact CD1-CB 3.96Å; L175-E180 HydrophobicContact CD1-CG 3.69Å; L175-P489 WeakPolarHBondContact O-CA 3.33Å; L175-A490 PolarHBondContact N-O 3.19Å; L175-A490 PolarHBondContact O-N 2.98Å; L175-F492 HydrophobicContact CD1-CE2 4.49Å; L175-F492 HydrophobicContact CD2-CD2 3.68Å; L175-F492 HydrophobicContact CD2-CE2 4.01Å; L175-F492 HydrophobicContact CG-CD2 4.43Å; L175-F492 HydrophobicContact CG-CE2 4.34Å
176L97.9Very high93.1Very high79 Ų7947.9 Ų47.941%0.41424%0.241SC..EExtended strand (participates in β ladder)trans-87.7107169.3-59.4-178.1000108.7Y178 P179 N487 P489L176-Y178 PolarHBondContact O-N 2.91Å; L176-P179 HydrophobicContact CB-CG 4.05Å; L176-P179 WeakPolarHBondContact O-CD 3.44Å; L176-N487 HydrophobicContact CB-CB 4.07Å; L176-N487 HydrophobicContact CD1-CB 4.33Å; L176-N487 HydrophobicContact CD2-CB 4.33Å; L176-N487 HydrophobicContact CG-CB 4.48Å; L176-P489 HydrophobicContact CD2-CB 4.13Å; L176-P489 HydrophobicContact CD2-CG 3.79Å
177V97.7Very high92.9Very high0 Ų045.3 Ų45.30%023%0.227CC..Hα-helixtrans-64.1-41.4-171.4171.90000112.5L175 E180 V181 T312 I315 N487 L488 A490 F492L175-V177 HydrophobicContact CD1-CG2 4.24Å; V177-E180 PolarHBondContact O-N 3.35Å; V177-V181 HydrophobicContact CG1-CG2 3.71Å; V177-V181 WeakPolarHBondContact O-CB 3.39Å; V177-V181 VanDerWaalsContact O-CG2 3.29Å; V177-V181 WeakPolarHBondContact O-CG2 3.36Å; V177-V181 PolarHBondContact O-N 2.83Å; V177-T312 HydrophobicContact CG1-CG2 4.37Å; V177-I315 HydrophobicContact CG1-CB 4.45Å; V177-I315 HydrophobicContact CG1-CD1 3.47Å; V177-I315 VanDerWaalsContact CG1-CD1 3.47Å; V177-I315 HydrophobicContact CG1-CG2 4.22Å; V177-N487 PolarHBondContact N-O 3.38Å; V177-N487 VanDerWaalsContact N-O 3.14Å; V177-L488 HydrophobicContact CB-CB 4.18Å; V177-L488 HydrophobicContact CB-CD2 4.06Å; V177-L488 HydrophobicContact CB-CG 4.29Å; V177-L488 WeakPolarHBondContact CB-O 3.47Å; V177-L488 HydrophobicContact CG1-CD2 4.03Å; V177-L488 HydrophobicContact CG2-CD2 4.44Å; V177-L488 VanDerWaalsContact CG2-O 3.25Å; V177-L488 WeakPolarHBondContact CG2-O 3.11Å; V177-L488 PolarHBondContact N-O 2.87Å; V177-L488 VanDerWaalsContact N-O 3.11Å; V177-A490 HydrophobicContact CG2-CB 3.64Å; V177-F492 HydrophobicContact CG2-CE2 3.75Å; V177-F492 HydrophobicContact CG2-CZ 4Å
178Y96.8Very high92.8Very high20 Ų2045.2 Ų45.28%0.07823%0.226CC..Hα-helixtrans-63.4-48.6-172.1-178.1-125.9000113.2L176 E180 V181 K182 T312 Y483 P484 N487L176-Y178 PolarHBondContact O-N 2.91Å; Y178-E180 VanDerWaalsContact C-N 3.34Å; Y178-E180 PolarHBondContact O-N 3.46Å; Y178-V181 PolarHBondContact O-N 3.06Å; Y178-K182 HydrophobicContact CD2-CG 4.41Å; Y178-K182 HydrophobicContact CE1-CD 4.14Å; Y178-K182 HydrophobicContact CE2-CD 4.28Å; Y178-K182 HydrophobicContact CE2-CG 4.09Å; Y178-K182 WeakPolarHBondContact O-CG 3.18Å; Y178-K182 PolarHBondContact O-N 3.13Å; Y178-T312 HydrophobicContact CD2-CG2 4.1Å; Y178-T312 WeakPolarHBondContact CD2-OG1 3.24Å; Y178-T312 HydrophobicContact CG-CG2 4.49Å; Y178-Y483 HydrophobicContact CE1-CD2 4.36Å; Y178-Y483 HydrophobicContact CE1-CG 4.22Å; Y178-P484 HydrophobicContact CG-CG 4.3Å; Y178-N487 PolarHBondContact N-O 2.64Å
179P94.1Very high92.7Very high40 Ų4044.3 Ų44.326%0.2622%0.222SC..Hα-helixtrans-55.6-44172-27.733.7000113.9L176 K182 R183 N487L176-P179 HydrophobicContact CB-CG 4.05Å; L176-P179 WeakPolarHBondContact O-CD 3.44Å; P179-K182 WeakPolarHBondContact O-CB 3.17Å; P179-K182 PolarHBondContact O-N 3.39Å; P179-R183 WeakPolarHBondContact O-CG 3.43Å; P179-R183 PolarHBondContact O-N 2.89Å; P179-N487 HydrophobicContact CG-CB 4.3Å
180E95.1Very high92.5Very high47 Ų4741 Ų4122%0.2220%0.197CC..Hα-helixtrans-70.1-39.3-177.3-65.8-53.1120.200112.4W167 L175 V177 Y178 K182 R183 L184W167-E180 HydrophobicContact CZ2-CB 3.75Å; L175-E180 HydrophobicContact CD1-CB 3.96Å; L175-E180 HydrophobicContact CD1-CG 3.69Å; V177-E180 PolarHBondContact O-N 3.35Å; Y178-E180 VanDerWaalsContact C-N 3.34Å; Y178-E180 PolarHBondContact O-N 3.46Å; E180-K182 VanDerWaalsContact C-N 3.32Å; E180-K182 PolarHBondContact O-N 3.45Å; E180-R183 PolarHBondContact O-N 2.98Å; E180-R183 IonicContact OE1-NE 3.74Å; E180-R183 PolarHBondContact OE1-NE 2.95Å; E180-L184 PolarHBondContact O-N 3.07Å
181V96.8Very high92.4Very high0 Ų040.5 Ų40.50%019%0.19CC..Hα-helixtrans-61.8-40.3171.5170.70000110.8W167 V177 Y178 L184 M185 A308 A311 I315 F457W167-V181 HydrophobicContact CH2-CG2 3.56Å; W167-V181 HydrophobicContact CZ2-CG2 4Å; V177-V181 HydrophobicContact CG1-CG2 3.71Å; V177-V181 WeakPolarHBondContact O-CB 3.39Å; V177-V181 VanDerWaalsContact O-CG2 3.29Å; V177-V181 WeakPolarHBondContact O-CG2 3.36Å; V177-V181 PolarHBondContact O-N 2.83Å; Y178-V181 PolarHBondContact O-N 3.06Å; V181-L184 PolarHBondContact O-N 3.29Å; V181-M185 HydrophobicContact CG1-CE 4.12Å; V181-M185 HydrophobicContact CG1-CG 4.26Å; V181-M185 VanDerWaalsContact O-CG 3.26Å; V181-M185 WeakPolarHBondContact O-CG 3.4Å; V181-M185 PolarHBondContact O-N 3.03Å; V181-A308 HydrophobicContact CG1-CB 3.95Å; V181-A311 HydrophobicContact CG1-CB 3.74Å; V181-I315 HydrophobicContact CG2-CD1 4.04Å; V181-F457 HydrophobicContact CG2-CZ 4.34Å
182K93Very high92.8Very high25 Ų2539.2 Ų39.211%0.10918%0.176CC..Hα-helixtrans-59.1-49.6174.8-75.1-173.874.3-166.10111.4Y178 P179 E180 L184 M185 F186 E217 H304 E305 A308Y178-K182 HydrophobicContact CD2-CG 4.41Å; Y178-K182 HydrophobicContact CE1-CD 4.14Å; Y178-K182 HydrophobicContact CE2-CD 4.28Å; Y178-K182 HydrophobicContact CE2-CG 4.09Å; Y178-K182 WeakPolarHBondContact O-CG 3.18Å; Y178-K182 PolarHBondContact O-N 3.13Å; P179-K182 WeakPolarHBondContact O-CB 3.17Å; P179-K182 PolarHBondContact O-N 3.39Å; E180-K182 VanDerWaalsContact C-N 3.32Å; E180-K182 PolarHBondContact O-N 3.45Å; K182-L184 VanDerWaalsContact C-N 3.32Å; K182-L184 PolarHBondContact O-N 3.38Å; K182-M185 PolarHBondContact O-N 3.48Å; K182-F186 PolarHBondContact O-N 3.04Å; K182-E217 IonicContact NZ-OE1 3.59Å; K182-E217 PolarHBondContact NZ-OE1 3.15Å; K182-H304 WeakPolarHBondContact CE-CE1 3.42Å; K182-H304 PolarHBondContact O-CD2 3.25Å; K182-H304 VanDerWaalsContact O-CD2 3.25Å; K182-H304 PolarHBondContact O-NE2 2.87Å; K182-E305 WeakPolarHBondContact CE-OE1 3.49Å; K182-E305 IonicContact NZ-OE1 3.33Å; K182-E305 PolarHBondContact NZ-OE1 2.84Å; K182-E305 VanDerWaalsContact NZ-OE1 3.11Å; K182-A308 HydrophobicContact CG-CB 3.92Å
183R91.1Very high93.2Very high102 Ų10231.5 Ų31.539%0.38514%0.14SC..Hα-helixtrans-55.5-46.9176.1-65.8-178.8-159.9-101.52.4111.5P179 E180 M185 F186 R187P179-R183 WeakPolarHBondContact O-CG 3.43Å; P179-R183 PolarHBondContact O-N 2.89Å; E180-R183 PolarHBondContact O-N 2.98Å; E180-R183 IonicContact OE1-NE 3.74Å; E180-R183 PolarHBondContact OE1-NE 2.95Å; R183-M185 PolarHBondContact O-N 2.97Å; R183-F186 WeakPolarHBondContact O-CB 3.42Å; R183-F186 PolarHBondContact O-N 3.33Å; R183-R187 PolarHBondContact O-N 3.45Å
184L94.3Very high93.2Very high0 Ų021.7 Ų21.70%010%0.103CC..Hα-helixtrans-57.8-49176.6172.259.5000112.1E159 V160 C163 E180 V181 K182 F186 R187 I188 F457E159-L184 HydrophobicContact CB-CD1 3.97Å; E159-L184 WeakPolarHBondContact O-CD1 3.38Å; V160-L184 HydrophobicContact CG2-CD2 4.28Å; C163-L184 HydrophobicContact CB-CD1 3.86Å; C163-L184 HydrophobicContact CB-CD2 4.09Å; C163-L184 HydrophobicContact CB-CG 4.39Å; E180-L184 PolarHBondContact O-N 3.07Å; V181-L184 PolarHBondContact O-N 3.29Å; K182-L184 VanDerWaalsContact C-N 3.32Å; K182-L184 PolarHBondContact O-N 3.38Å; L184-F186 PolarHBondContact O-N 3.44Å; L184-R187 PolarHBondContact O-N 3.34Å; L184-I188 HydrophobicContact CD1-CD1 3.72Å; L184-I188 HydrophobicContact CD1-CG1 4.06Å; L184-I188 HydrophobicContact CG-CD1 3.89Å; L184-I188 WeakPolarHBondContact O-CG1 3.29Å; L184-I188 PolarHBondContact O-N 2.8Å; L184-F457 HydrophobicContact CD2-CD2 4.12Å; L184-F457 HydrophobicContact CD2-CE2 3.75Å
185M95.1Very high92.9Very high1 Ų121.9 Ų21.91%0.00511%0.105CC..Hα-helixtrans-64.6-31.1179.7-63.9-57.3144.200112.1V181 K182 R183 I188 A189 T307 A308 A311 L453 F457V181-M185 HydrophobicContact CG1-CE 4.12Å; V181-M185 HydrophobicContact CG1-CG 4.26Å; V181-M185 VanDerWaalsContact O-CG 3.26Å; V181-M185 WeakPolarHBondContact O-CG 3.4Å; V181-M185 PolarHBondContact O-N 3.03Å; K182-M185 PolarHBondContact O-N 3.48Å; R183-M185 PolarHBondContact O-N 2.97Å; M185-I188 HydrophobicContact SD-CD1 4.37Å; M185-A189 WeakPolarHBondContact O-CB 3.31Å; M185-A189 PolarHBondContact O-N 3.16Å; M185-T307 WeakPolarHBondContact CG-OG1 3.47Å; M185-A308 HydrophobicContact CB-CB 4.29Å; M185-A308 HydrophobicContact CG-CB 3.84Å; M185-A311 HydrophobicContact CE-CB 3.77Å; M185-L453 HydrophobicContact CE-CD2 4.02Å; M185-L453 HydrophobicContact SD-CD1 4.16Å; M185-L453 HydrophobicContact SD-CD2 3.72Å; M185-F457 HydrophobicContact CE-CD2 4.33Å; M185-F457 HydrophobicContact CE-CE2 4.43Å
186F90.6Very high92.2Very high4 Ų421 Ų212%0.01810%0.102CC..Hα-helixtrans-67.6-47.6175.7-175.3-93.8000110.7K182 R183 L184 I188 A189 M190 L212 V213 F216 H304K182-F186 PolarHBondContact O-N 3.04Å; R183-F186 WeakPolarHBondContact O-CB 3.42Å; R183-F186 PolarHBondContact O-N 3.33Å; L184-F186 PolarHBondContact O-N 3.44Å; F186-I188 PolarHBondContact O-N 2.91Å; F186-A189 PolarHBondContact O-N 3.15Å; F186-M190 HydrophobicContact CD1-CG 3.81Å; F186-M190 HydrophobicContact CE1-CG 3.44Å; F186-M190 VanDerWaalsContact CE1-CG 3.44Å; F186-M190 HydrophobicContact CE1-SD 4.05Å; F186-M190 HydrophobicContact CE2-CG 4.42Å; F186-M190 HydrophobicContact CE2-SD 4.47Å; F186-M190 HydrophobicContact CG-CG 4.47Å; F186-M190 HydrophobicContact CZ-CG 3.79Å; F186-M190 HydrophobicContact CZ-SD 3.82Å; F186-M190 WeakPolarHBondContact O-CG 3.38Å; F186-M190 PolarHBondContact O-N 3.24Å; F186-L212 HydrophobicContact CZ-CB 4.26Å; F186-V213 HydrophobicContact CD1-CB 4.49Å; F186-V213 HydrophobicContact CD1-CG2 3.38Å; F186-V213 HydrophobicContact CE1-CB 4.32Å; F186-V213 HydrophobicContact CE1-CG2 3.37Å; F186-V213 HydrophobicContact CG-CG2 4.1Å; F186-V213 HydrophobicContact CZ-CG2 4.12Å; F186-F216 HydrophobicContact CD2-CB 4.44Å; F186-F216 AromaticContact CD2-CD1 3.89Å; F186-F216 HydrophobicContact CD2-CD1 3.89Å; F186-F216 HydrophobicContact CD2-CE1 4.31Å; F186-F216 HydrophobicContact CD2-CG 4.15Å; F186-F216 HydrophobicContact CE2-CB 3.66Å; F186-F216 AromaticContact CE2-CD1 3.86Å; F186-F216 HydrophobicContact CE2-CD1 3.86Å; F186-F216 HydrophobicContact CE2-CD2 4.16Å; F186-F216 AromaticContact CE2-CG 3.63Å; F186-F216 HydrophobicContact CE2-CG 3.63Å; F186-F216 HydrophobicContact CZ-CB 4.35Å; F186-H304 PolarHBondContact N-CD2 3.43Å
187R90.4Very high90.9Very high46 Ų4621.2 Ų21.217%0.17410%0.1CC..Hα-helixtrans-59.8-47176.7-69.3-164.7-56.3-93.6-0.1112.5E159 R183 L184 A189 M190 R191 E209E159-R187 WeakPolarHBondContact OE2-CB 3.3Å; E159-R187 IonicContact OE2-NE 2.65Å; E159-R187 PolarHBondContact OE2-NE 3.35Å; R183-R187 PolarHBondContact O-N 3.45Å; L184-R187 PolarHBondContact O-N 3.34Å; R187-A189 VanDerWaalsContact C-N 3.3Å; R187-A189 PolarHBondContact O-N 3.3Å; R187-M190 PolarHBondContact O-N 3.08Å; R187-R191 PolarHBondContact O-N 3.11Å; R187-E209 WeakPolarHBondContact CD-OE1 3.31Å; R187-E209 WeakPolarHBondContact CG-OE1 3.21Å
188I93.6Very high89.3Confident1 Ų125 Ų251%0.00513%0.125CC..Hα-helixtrans-56.9-46.3174.5-69.1171.1000110.4I156 E159 V160 L184 M185 F186 R191 I192 F449 L453I156-I188 HydrophobicContact CG1-CG2 4.21Å; I156-I188 HydrophobicContact CG2-CD1 4.38Å; E159-I188 HydrophobicContact CB-CD1 4.22Å; E159-I188 HydrophobicContact CB-CG1 3.58Å; E159-I188 HydrophobicContact CG-CG1 3.93Å; V160-I188 HydrophobicContact CG2-CD1 4.13Å; L184-I188 HydrophobicContact CD1-CD1 3.72Å; L184-I188 HydrophobicContact CD1-CG1 4.06Å; L184-I188 HydrophobicContact CG-CD1 3.89Å; L184-I188 WeakPolarHBondContact O-CG1 3.29Å; L184-I188 PolarHBondContact O-N 2.8Å; M185-I188 HydrophobicContact SD-CD1 4.37Å; F186-I188 PolarHBondContact O-N 2.91Å; I188-R191 PolarHBondContact O-N 2.89Å; I188-I192 HydrophobicContact CG2-CD1 3.51Å; I188-I192 HydrophobicContact CG2-CG1 4.38Å; I188-I192 VanDerWaalsContact O-CB 3.3Å; I188-I192 WeakPolarHBondContact O-CB 3.21Å; I188-I192 WeakPolarHBondContact O-CG1 3.33Å; I188-I192 PolarHBondContact O-N 3.5Å; I188-F449 HydrophobicContact CG2-CZ 4.29Å; I188-L453 HydrophobicContact CD1-CD1 4.49Å; I188-L453 HydrophobicContact CG2-CD1 3.79Å
189A91.9Very high87.4Confident2 Ų227.6 Ų27.62%0.01716%0.158CC..Hα-helixtrans-64.8-40.617900000112.2M185 F186 R187 L193 L300M185-A189 WeakPolarHBondContact O-CB 3.31Å; M185-A189 PolarHBondContact O-N 3.16Å; F186-A189 PolarHBondContact O-N 3.15Å; R187-A189 VanDerWaalsContact C-N 3.3Å; R187-A189 PolarHBondContact O-N 3.3Å; A189-L193 HydrophobicContact CB-CD1 3.84Å; A189-L193 HydrophobicContact CB-CG 4.42Å; A189-L193 WeakPolarHBondContact O-CA 3.34Å; A189-L193 WeakPolarHBondContact O-CB 3.21Å; A189-L193 WeakPolarHBondContact O-CG 3.5Å; A189-L193 PolarHBondContact O-N 3.44Å; A189-L300 HydrophobicContact CB-CD2 3.78Å
190M89.3Confident85.7Confident20 Ų2027.4 Ų27.410%0.09916%0.158CC..Hα-helixtrans-62.3-46.1176.8-75.1-65-65.100112.1F186 R187 L194 G195 C196 L212 L300F186-M190 HydrophobicContact CD1-CG 3.81Å; F186-M190 HydrophobicContact CE1-CG 3.44Å; F186-M190 VanDerWaalsContact CE1-CG 3.44Å; F186-M190 HydrophobicContact CE1-SD 4.05Å; F186-M190 HydrophobicContact CE2-CG 4.42Å; F186-M190 HydrophobicContact CE2-SD 4.47Å; F186-M190 HydrophobicContact CG-CG 4.47Å; F186-M190 HydrophobicContact CZ-CG 3.79Å; F186-M190 HydrophobicContact CZ-SD 3.82Å; F186-M190 WeakPolarHBondContact O-CG 3.38Å; F186-M190 PolarHBondContact O-N 3.24Å; R187-M190 PolarHBondContact O-N 3.08Å; M190-L194 HydrophobicContact CE-CD1 4.27Å; M190-L194 CarbonylContact O-C 3.49Å; M190-L194 WeakPolarHBondContact O-CB 3.34Å; M190-L194 PolarHBondContact O-N 3.45Å; M190-L194 HydrophobicContact SD-CD1 3.8Å; M190-G195 PolarHBondContact O-N 3.43Å; M190-C196 HydrophobicContact CB-CB 4.44Å; M190-C196 HydrophobicContact CE-CB 3.82Å; M190-C196 PolarHBondContact O-N 2.65Å; M190-C196 VanDerWaalsContact O-N 3.16Å; M190-L212 HydrophobicContact CE-CD1 4.11Å; M190-L300 HydrophobicContact SD-CD1 4.21Å; M190-L300 HydrophobicContact SD-CD2 4.03Å
191R90.4Very high83.6Confident23 Ų2330 Ų309%0.08719%0.187CC..Hα-helixtrans-69.2-51.5179-68-176.574.4-164.1-2.1111.7V155 E158 E159 R187 I188 G195 C196 E197V155-R191 HydrophobicContact CG1-CB 3.88Å; E158-R191 IonicContact OE2-CZ 3.39Å; E158-R191 VanDerWaalsContact OE2-CZ 3.29Å; E158-R191 IonicContact OE2-NH1 2.93Å; E158-R191 PolarHBondContact OE2-NH1 3.44Å; E158-R191 IonicContact OE2-NH2 3.11Å; E158-R191 PolarHBondContact OE2-NH2 3.34Å; E159-R191 WeakPolarHBondContact OE1-CD 3.29Å; E159-R191 IonicContact OE1-CZ 2.79Å; E159-R191 IonicContact OE1-NE 3.45Å; E159-R191 IonicContact OE1-NH1 3.61Å; E159-R191 PolarHBondContact OE1-NH1 3.44Å; R187-R191 PolarHBondContact O-N 3.11Å; I188-R191 PolarHBondContact O-N 2.89Å; R191-G195 WeakPolarHBondContact O-CA 3.48Å; R191-G195 PolarHBondContact O-N 2.93Å; R191-C196 WeakPolarHBondContact CG-O 3.39Å; R191-E197 IonicContact CZ-OE2 2.69Å; R191-E197 IonicContact NE-OE1 3.56Å; R191-E197 IonicContact NE-OE2 2.8Å; R191-E197 PolarHBondContact NE-OE2 2.91Å; R191-E197 IonicContact NH2-OE2 2.68Å; R191-E197 PolarHBondContact NH2-OE2 2.85Å
192I92.3Very high81.4Confident3 Ų331 Ų312%0.01520%0.196CC..Hα-helixtrans-78.6-39.3-172.1-64.3175000112.6Y152 V155 I156 I188 D271 A272 F449Y152-I192 HydrophobicContact CD1-CG2 3.62Å; Y152-I192 HydrophobicContact CD2-CG2 3.44Å; Y152-I192 VanDerWaalsContact CD2-CG2 3.44Å; Y152-I192 HydrophobicContact CE1-CG2 3.79Å; Y152-I192 HydrophobicContact CE2-CG2 3.61Å; Y152-I192 HydrophobicContact CG-CG2 3.46Å; Y152-I192 VanDerWaalsContact CG-CG2 3.46Å; V155-I192 HydrophobicContact CB-CD1 4.49Å; V155-I192 HydrophobicContact CB-CG1 4.24Å; V155-I192 HydrophobicContact CG1-CD1 4.34Å; V155-I192 HydrophobicContact CG1-CG1 3.85Å; I156-I192 HydrophobicContact CD1-CD1 3.93Å; I156-I192 HydrophobicContact CG1-CD1 3.29Å; I188-I192 HydrophobicContact CG2-CD1 3.51Å; I188-I192 HydrophobicContact CG2-CG1 4.38Å; I188-I192 VanDerWaalsContact O-CB 3.3Å; I188-I192 WeakPolarHBondContact O-CB 3.21Å; I188-I192 WeakPolarHBondContact O-CG1 3.33Å; I188-I192 PolarHBondContact O-N 3.5Å; I192-D271 WeakPolarHBondContact O-CA 3.44Å; I192-D271 WeakPolarHBondContact O-CB 3.37Å; I192-A272 PolarHBondContact O-N 2.99Å; I192-F449 HydrophobicContact CD1-CE2 3.86Å; I192-F449 HydrophobicContact CD1-CZ 4.13Å; I192-F449 HydrophobicContact CG2-CE2 3.83Å; I192-F449 HydrophobicContact CG2-CZ 4.3Å
193L89.6Confident79.4Confident3 Ų330.3 Ų30.32%0.01619%0.194CC..Hα-helixtrans-89.5-30.1-172.9-50.1175.6000112.1F144 A189 A272 L273 L299F144-L193 HydrophobicContact CE1-CD2 3.84Å; F144-L193 HydrophobicContact CZ-CD2 3.97Å; A189-L193 HydrophobicContact CB-CD1 3.84Å; A189-L193 HydrophobicContact CB-CG 4.42Å; A189-L193 WeakPolarHBondContact O-CA 3.34Å; A189-L193 WeakPolarHBondContact O-CB 3.21Å; A189-L193 WeakPolarHBondContact O-CG 3.5Å; A189-L193 PolarHBondContact O-N 3.44Å; L193-A272 HydrophobicContact CB-CB 4.39Å; L193-A272 HydrophobicContact CD2-CB 4.02Å; L193-L273 VanDerWaalsContact O-CB 3.28Å; L193-L273 WeakPolarHBondContact O-CB 3.36Å; L193-L273 PolarHBondContact O-N 2.92Å; L193-L299 HydrophobicContact CB-CB 4.42Å; L193-L299 HydrophobicContact CD1-CB 4.06Å; L193-L299 VanDerWaalsContact CD1-O 3.31Å; L193-L299 WeakPolarHBondContact CD1-O 3.31Å
194L88.4Confident77.8Confident2 Ų226.3 Ų26.31%0.0118%0.184CC..Hα-helixtrans-115.3-13-178.4-53.5-173000114M190 C196 I249 N252 K256 L273 L300M190-L194 HydrophobicContact CE-CD1 4.27Å; M190-L194 CarbonylContact O-C 3.49Å; M190-L194 WeakPolarHBondContact O-CB 3.34Å; M190-L194 PolarHBondContact O-N 3.45Å; M190-L194 HydrophobicContact SD-CD1 3.8Å; L194-C196 VanDerWaalsContact C-N 3.29Å; L194-C196 PolarHBondContact O-N 3.36Å; L194-I249 HydrophobicContact CD1-CD1 4.4Å; L194-I249 HydrophobicContact CD1-CG1 4.01Å; L194-N252 PolarHBondContact O-ND2 3.47Å; L194-K256 WeakPolarHBondContact O-CE 3.5Å; L194-K256 PolarHBondContact O-NZ 2.91Å; L194-L273 HydrophobicContact CD2-CD2 4.2Å; L194-L300 HydrophobicContact CD1-CD1 3.65Å; L194-L300 HydrophobicContact CD1-CD2 4.07Å; L194-L300 HydrophobicContact CD1-CG 4.01Å; L194-L300 HydrophobicContact CG-CD1 4.46Å; L194-L300 HydrophobicContact CG-CD2 4.17Å; L194-L300 HydrophobicContact CG-CG 4.29Å
195G86.1Confident76.3Confident17 Ų1728.4 Ų28.418%0.17521%0.206CC..  trans66.631.2-175.200000112.9M190 R191 E197M190-G195 PolarHBondContact O-N 3.43Å; R191-G195 WeakPolarHBondContact O-CA 3.48Å; R191-G195 PolarHBondContact O-N 2.93Å; G195-E197 PolarHBondContact O-N 3.35Å
196C81.2Confident75Confident7 Ų736.7 Ų36.75%0.04725%0.245CC..  trans-86.797.9173.9-70.80000109.2M190 R191 L194 N252M190-C196 HydrophobicContact CB-CB 4.44Å; M190-C196 HydrophobicContact CE-CB 3.82Å; M190-C196 PolarHBondContact O-N 2.65Å; M190-C196 VanDerWaalsContact O-N 3.16Å; R191-C196 WeakPolarHBondContact CG-O 3.39Å; L194-C196 VanDerWaalsContact C-N 3.29Å; L194-C196 PolarHBondContact O-N 3.36Å; C196-N252 PolarHBondContact SG-ND2 3.4Å; C196-N252 VanDerWaalsContact SG-ND2 3.38Å
197E71.5Confident74Confident82 Ų8244.8 Ų44.838%0.38328%0.282SS..  trans-77.3143.2175.9-68.1-58.114700111.8R191 G195 G199 S200 S203R191-E197 IonicContact CZ-OE2 2.69Å; R191-E197 IonicContact NE-OE1 3.56Å; R191-E197 IonicContact NE-OE2 2.8Å; R191-E197 PolarHBondContact NE-OE2 2.91Å; R191-E197 IonicContact NH2-OE2 2.68Å; R191-E197 PolarHBondContact NH2-OE2 2.85Å; G195-E197 PolarHBondContact O-N 3.35Å; E197-G199 PolarHBondContact O-N 3.48Å; E197-S200 VanDerWaalsContact O-CB 3.31Å; E197-S200 WeakPolarHBondContact O-CB 3.26Å; E197-S200 PolarHBondContact O-N 2.98Å; E197-S200 PolarHBondContact O-OG 3.34Å; E197-S203 WeakPolarHBondContact O-CB 3.35Å; E197-S203 PolarHBondContact O-OG 3.13Å; E197-S203 VanDerWaalsContact O-OG 3.05Å
198P63.8Low73.1Confident79 Ų7946 Ų4651%0.51329%0.292SS..THydrogen-bonded Turntrans-54.3133.4173.6-22.732.5000111.9S200P198-S200 PolarHBondContact O-N 3.42Å
199G56.6Low72.2Confident76 Ų7648.8 Ų48.878%0.78431%0.305SS*.THydrogen-bonded Turntrans72.86.3179.300000115.7E197 S203E197-G199 PolarHBondContact O-N 3.48Å; G199-S203 PolarHBondContact N-OG 3.2Å; G199-S203 VanDerWaalsContact N-OG 3.15Å
200S58.3Low71.6Confident36 Ų3652.2 Ų52.225%0.25232%0.321SS..SBendtrans-76.8155.7173.170.80000111.7E197 P198 A202 S203 G204E197-S200 VanDerWaalsContact O-CB 3.31Å; E197-S200 WeakPolarHBondContact O-CB 3.26Å; E197-S200 PolarHBondContact O-N 2.98Å; E197-S200 PolarHBondContact O-OG 3.34Å; P198-S200 PolarHBondContact O-N 3.42Å; S200-A202 PolarHBondContact O-N 3.41Å; S200-A202 PolarHBondContact OG-N 3.21Å; S200-S203 PolarHBondContact N-OG 3.2Å; S200-S203 PolarHBondContact O-N 3.01Å; S200-S203 PolarHBondContact O-OG 3.12Å; S200-S203 PolarHBondContact OG-N 3.18Å; S200-S203 PolarHBondContact OG-OG 3.34Å; S200-G204 PolarHBondContact O-N 3.24Å
201A51.2Low71.4Confident101 Ų10156 Ų5684%0.83534%0.338SS*.THydrogen-bonded Turntrans-56.1-21.6171.100000112.9R248A201-R248 PolarHBondContact O-NH1 3.01Å; A201-R248 PolarHBondContact O-NH2 3.43Å
202A50.8Low71.2Confident22 Ų2255.6 Ų55.618%0.18234%0.338CS..THydrogen-bonded Turntrans-91.1-13.9177.400000114.7S200 R248S200-A202 PolarHBondContact O-N 3.41Å; S200-A202 PolarHBondContact OG-N 3.21Å; A202-R248 PolarHBondContact O-NE 3.3Å; A202-R248 PolarHBondContact O-NH2 3.28Å
203S50.4Low70.8Confident10 Ų1056.2 Ų56.27%0.0734%0.342CS..THydrogen-bonded Turntrans-89.7-30.816660.80000111.5E197 G199 S200 R248E197-S203 WeakPolarHBondContact O-CB 3.35Å; E197-S203 PolarHBondContact O-OG 3.13Å; E197-S203 VanDerWaalsContact O-OG 3.05Å; G199-S203 PolarHBondContact N-OG 3.2Å; G199-S203 VanDerWaalsContact N-OG 3.15Å; S200-S203 PolarHBondContact N-OG 3.2Å; S200-S203 PolarHBondContact O-N 3.01Å; S200-S203 PolarHBondContact O-OG 3.12Å; S200-S203 PolarHBondContact OG-N 3.18Å; S200-S203 PolarHBondContact OG-OG 3.34Å; S203-R248 PolarHBondContact O-NH2 3.49Å
204G57.5Low70.8Confident17 Ų1761.2 Ų61.218%0.17537%0.365CS..  trans76.7-176.4-169.700000110S200 D208S200-G204 PolarHBondContact O-N 3.24Å; G204-D208 WeakPolarHBondContact CA-OD2 3.3Å
205G64.2Low71Confident45 Ų4561.5 Ų61.546%0.46437%0.368SS..SBendtrans-68.9177.4174.200000112.1E207 D208 E209G205-E207 PolarHBondContact O-N 2.85Å; G205-E207 VanDerWaalsContact O-N 3.16Å; G205-D208 PolarHBondContact N-OD2 2.87Å; G205-D208 WeakPolarHBondContact O-CB 3.43Å; G205-D208 PolarHBondContact O-N 3.23Å; G205-E209 PolarHBondContact O-N 3.07Å
206E66.9Low71.2Confident175 Ų17560.8 Ų60.882%0.81836%0.36SS*.Hα-helixtrans-54.2-34174.3-69.3-177.8170.800112.5D208 E209 Q210E206-D208 VanDerWaalsContact C-N 3.34Å; E206-D208 PolarHBondContact O-N 3.44Å; E206-E209 PolarHBondContact O-N 3.44Å; E206-Q210 WeakPolarHBondContact O-CB 3.07Å; E206-Q210 PolarHBondContact O-N 3.2Å
207E68.8Low71.6Confident173 Ų17363.6 Ų63.681%0.80837%0.372SS*.Hα-helixtrans-64.1-36.1175.8-66.2-176.3172.100112.8G205 Q211G205-E207 PolarHBondContact O-N 2.85Å; G205-E207 VanDerWaalsContact O-N 3.16Å; E207-Q211 WeakPolarHBondContact O-CB 3.44Å; E207-Q211 PolarHBondContact O-N 2.85Å
208D72.9Confident72.6Confident72 Ų7261.7 Ų61.739%0.38536%0.364SS..Hα-helixtrans-72.7-39.1179.1-68.1-39.4000111.1G204 G205 E206 Q211 L212G204-D208 WeakPolarHBondContact CA-OD2 3.3Å; G205-D208 PolarHBondContact N-OD2 2.87Å; G205-D208 WeakPolarHBondContact O-CB 3.43Å; G205-D208 PolarHBondContact O-N 3.23Å; E206-D208 VanDerWaalsContact C-N 3.34Å; E206-D208 PolarHBondContact O-N 3.44Å; D208-Q211 PolarHBondContact O-N 2.92Å; D208-L212 WeakPolarHBondContact O-CG 3.25Å; D208-L212 PolarHBondContact O-N 2.86Å
209E74.4Confident74Confident59 Ų5958 Ų5828%0.27634%0.339SS..Hα-helixtrans-63-46.7174.9-173.9-179.3159.400111R187 G205 E206 Q211 L212 V213R187-E209 WeakPolarHBondContact CD-OE1 3.31Å; R187-E209 WeakPolarHBondContact CG-OE1 3.21Å; G205-E209 PolarHBondContact O-N 3.07Å; E206-E209 PolarHBondContact O-N 3.44Å; E209-Q211 VanDerWaalsContact C-N 3.3Å; E209-Q211 PolarHBondContact O-N 3.12Å; E209-L212 WeakPolarHBondContact O-CB 3.35Å; E209-L212 PolarHBondContact O-N 2.95Å; E209-L212 VanDerWaalsContact O-N 3.13Å; E209-V213 WeakPolarHBondContact O-CG2 3.44Å; E209-V213 PolarHBondContact O-N 3.44Å
210Q78.5Confident75.6Confident75 Ų7555.2 Ų55.235%0.3531%0.307SS..Hα-helixtrans-61-40.3177.7-177.357.733.400111.3E206 L212 V213 E214E206-Q210 WeakPolarHBondContact O-CB 3.07Å; E206-Q210 PolarHBondContact O-N 3.2Å; Q210-L212 VanDerWaalsContact C-N 3.35Å; Q210-L212 PolarHBondContact O-N 2.9Å; Q210-V213 PolarHBondContact O-N 3.45Å; Q210-E214 PolarHBondContact NE2-OE1 3.24Å; Q210-E214 WeakPolarHBondContact O-CG 3.32Å; Q210-E214 PolarHBondContact O-N 3.29Å
211Q85.3Confident77.2Confident99 Ų9961.8 Ų61.846%0.46333%0.327SS..Hα-helixtrans-63.1-39.2174.9-172.3-176.977.800112.3E207 D208 E209 E214 A215 L244E207-Q211 WeakPolarHBondContact O-CB 3.44Å; E207-Q211 PolarHBondContact O-N 2.85Å; D208-Q211 PolarHBondContact O-N 2.92Å; E209-Q211 VanDerWaalsContact C-N 3.3Å; E209-Q211 PolarHBondContact O-N 3.12Å; Q211-E214 PolarHBondContact O-N 2.75Å; Q211-A215 VanDerWaalsContact O-CB 3.3Å; Q211-A215 WeakPolarHBondContact O-CB 3.49Å; Q211-A215 PolarHBondContact O-N 3.32Å; Q211-L244 HydrophobicContact CG-CD2 4.09Å
212L85.7Confident79.2Confident14 Ų1457.9 Ų57.97%0.07329%0.292CS..Hα-helixtrans-66.8-41.2176.4-72.3167000112.2F186 M190 D208 E209 Q210 A215 F216 R248F186-L212 HydrophobicContact CZ-CB 4.26Å; M190-L212 HydrophobicContact CE-CD1 4.11Å; D208-L212 WeakPolarHBondContact O-CG 3.25Å; D208-L212 PolarHBondContact O-N 2.86Å; E209-L212 WeakPolarHBondContact O-CB 3.35Å; E209-L212 PolarHBondContact O-N 2.95Å; E209-L212 VanDerWaalsContact O-N 3.13Å; Q210-L212 VanDerWaalsContact C-N 3.35Å; Q210-L212 PolarHBondContact O-N 2.9Å; L212-A215 PolarHBondContact O-N 3.02Å; L212-F216 VanDerWaalsContact O-CB 3.26Å; L212-F216 WeakPolarHBondContact O-CB 3.31Å; L212-F216 PolarHBondContact O-N 3.11Å; L212-R248 HydrophobicContact CD1-CG 3.93Å; L212-R248 HydrophobicContact CD2-CB 3.81Å; L212-R248 HydrophobicContact CD2-CG 3.97Å
213V84.4Confident81Confident17 Ų1756.9 Ų56.910%0.10328%0.283CS..Hα-helixtrans-57.8-51.4173.4173.40000109.7F186 E209 Q210 A215 F216 E217F186-V213 HydrophobicContact CD1-CB 4.49Å; F186-V213 HydrophobicContact CD1-CG2 3.38Å; F186-V213 HydrophobicContact CE1-CB 4.32Å; F186-V213 HydrophobicContact CE1-CG2 3.37Å; F186-V213 HydrophobicContact CG-CG2 4.1Å; F186-V213 HydrophobicContact CZ-CG2 4.12Å; E209-V213 WeakPolarHBondContact O-CG2 3.44Å; E209-V213 PolarHBondContact O-N 3.44Å; Q210-V213 PolarHBondContact O-N 3.45Å; V213-A215 PolarHBondContact O-N 2.61Å; V213-F216 WeakPolarHBondContact O-CB 3.46Å; V213-F216 PolarHBondContact O-N 3.09Å; V213-F216 VanDerWaalsContact O-N 3.14Å; V213-E217 HydrophobicContact CG1-CG 4.45Å; V213-E217 WeakPolarHBondContact O-CG 3.22Å; V213-E217 PolarHBondContact O-N 3.38Å
214E89.3Confident82.8Confident107 Ų10761 Ų6150%0.530%0.3SS..Hα-helixtrans-62.1-42.8-179.3-74174.6-16600112.5Q210 Q211 F216 E217 E218Q210-E214 PolarHBondContact NE2-OE1 3.24Å; Q210-E214 WeakPolarHBondContact O-CG 3.32Å; Q210-E214 PolarHBondContact O-N 3.29Å; Q211-E214 PolarHBondContact O-N 2.75Å; E214-F216 VanDerWaalsContact C-N 3.31Å; E214-F216 PolarHBondContact O-N 2.96Å; E214-E217 PolarHBondContact O-N 3.17Å; E214-E218 WeakPolarHBondContact O-CB 3.24Å; E214-E218 PolarHBondContact O-N 3.48Å
215A92.4Very high84.4Confident9 Ų961.3 Ų61.37%0.07430%0.3CS..Hα-helixtrans-60-44.3174.200000110.8Q211 L212 V213 E218 M219 A241 L244 I245Q211-A215 VanDerWaalsContact O-CB 3.3Å; Q211-A215 WeakPolarHBondContact O-CB 3.49Å; Q211-A215 PolarHBondContact O-N 3.32Å; L212-A215 PolarHBondContact O-N 3.02Å; V213-A215 PolarHBondContact O-N 2.61Å; A215-E218 PolarHBondContact O-N 2.98Å; A215-M219 WeakPolarHBondContact O-CB 3.32Å; A215-M219 PolarHBondContact O-N 2.98Å; A215-A241 WeakPolarHBondContact O-CB 3.07Å; A215-L244 HydrophobicContact CB-CD2 3.8Å; A215-L244 HydrophobicContact CB-CG 4.38Å; A215-I245 HydrophobicContact CB-CD1 4.33Å; A215-I245 HydrophobicContact CB-CG1 3.99Å
216F90.6Very high85.6Confident2 Ų265.2 Ų65.21%0.00931%0.309CS..Hα-helixtrans-66.3-40179.1-173.8-94.7000112.6F186 L212 V213 E214 M219 T220 I245 L300 H304F186-F216 HydrophobicContact CD2-CB 4.44Å; F186-F216 AromaticContact CD2-CD1 3.89Å; F186-F216 HydrophobicContact CD2-CD1 3.89Å; F186-F216 HydrophobicContact CD2-CE1 4.31Å; F186-F216 HydrophobicContact CD2-CG 4.15Å; F186-F216 HydrophobicContact CE2-CB 3.66Å; F186-F216 AromaticContact CE2-CD1 3.86Å; F186-F216 HydrophobicContact CE2-CD1 3.86Å; F186-F216 HydrophobicContact CE2-CD2 4.16Å; F186-F216 AromaticContact CE2-CG 3.63Å; F186-F216 HydrophobicContact CE2-CG 3.63Å; F186-F216 HydrophobicContact CZ-CB 4.35Å; L212-F216 VanDerWaalsContact O-CB 3.26Å; L212-F216 WeakPolarHBondContact O-CB 3.31Å; L212-F216 PolarHBondContact O-N 3.11Å; V213-F216 WeakPolarHBondContact O-CB 3.46Å; V213-F216 PolarHBondContact O-N 3.09Å; V213-F216 VanDerWaalsContact O-N 3.14Å; E214-F216 VanDerWaalsContact C-N 3.31Å; E214-F216 PolarHBondContact O-N 2.96Å; F216-M219 HydrophobicContact CD2-CE 3.56Å; F216-M219 HydrophobicContact CE2-CE 3.62Å; F216-M219 HydrophobicContact CG-CE 4.47Å; F216-M219 PolarHBondContact O-N 3.21Å; F216-T220 HydrophobicContact CD1-CG2 4.15Å; F216-T220 HydrophobicContact CE1-CG2 3.78Å; F216-T220 HydrophobicContact CZ-CG2 4.02Å; F216-T220 WeakPolarHBondContact O-CB 3.29Å; F216-T220 WeakPolarHBondContact O-CG2 3.29Å; F216-T220 PolarHBondContact O-N 2.83Å; F216-T220 PolarHBondContact O-OG1 2.93Å; F216-I245 HydrophobicContact CB-CD1 4.16Å; F216-I245 HydrophobicContact CD2-CD1 4.2Å; F216-L300 HydrophobicContact CE2-CB 3.73Å; F216-L300 HydrophobicContact CZ-CB 4.22Å; F216-H304 HydrophobicContact CE1-CB 3.92Å; F216-H304 AromaticContact CE1-CE1 3.95Å; F216-H304 AromaticContact CE1-CG 3.71Å; F216-H304 AromaticContact CE1-ND1 3.39Å; F216-H304 WeakPolarHBondContact CE1-ND1 3.34Å; F216-H304 HydrophobicContact CZ-CB 4.09Å
217E89.5Confident86.6Confident65 Ų6560.9 Ų60.930%0.30430%0.296SS..Hα-helixtrans-64.2-41.5173.2-68.5-150.6131.200112.5K182 V213 E214 T220 R221K182-E217 IonicContact NZ-OE1 3.59Å; K182-E217 PolarHBondContact NZ-OE1 3.15Å; V213-E217 HydrophobicContact CG1-CG 4.45Å; V213-E217 WeakPolarHBondContact O-CG 3.22Å; V213-E217 PolarHBondContact O-N 3.38Å; E214-E217 PolarHBondContact O-N 3.17Å; E217-T220 WeakPolarHBondContact CA-OG1 3.26Å; E217-T220 PolarHBondContact O-N 2.91Å; E217-T220 PolarHBondContact O-OG1 3.44Å; E217-R221 WeakPolarHBondContact O-CB 3.28Å; E217-R221 PolarHBondContact O-N 3.36Å
218E93.3Very high87.7Confident43 Ų4357 Ų5720%0.20128%0.28CS..Hα-helixtrans-67-38.7176.3-17263.5-163.600111.2E214 A215 R221 N222 R237 A241E214-E218 WeakPolarHBondContact O-CB 3.24Å; E214-E218 PolarHBondContact O-N 3.48Å; A215-E218 PolarHBondContact O-N 2.98Å; E218-R221 IonicContact OE2-CZ 2.72Å; E218-R221 IonicContact OE2-NH1 3.59Å; E218-R221 PolarHBondContact OE2-NH1 2.86Å; E218-N222 PolarHBondContact O-N 2.93Å; E218-N222 PolarHBondContact O-ND2 3.35Å; E218-N222 PolarHBondContact OE1-ND2 2.93Å; E218-R237 HydrophobicContact CG-CB 4.43Å; E218-R237 WeakPolarHBondContact OE1-CB 3.41Å; E218-R237 WeakPolarHBondContact OE1-CD 3.46Å; E218-A241 HydrophobicContact CB-CB 4.19Å; E218-A241 HydrophobicContact CG-CB 4.36Å
219M93.9Very high88.6Confident0 Ų058.4 Ų58.40%029%0.287CS..Hα-helixtrans-59.9-52.1173.3-176.7-173.76800111I119 A215 F216 N222 L223 A241 R242 I245 T297I119-M219 HydrophobicContact CG2-CG 3.46Å; I119-M219 VanDerWaalsContact CG2-CG 3.46Å; I119-M219 HydrophobicContact CG2-SD 4.33Å; A215-M219 WeakPolarHBondContact O-CB 3.32Å; A215-M219 PolarHBondContact O-N 2.98Å; F216-M219 HydrophobicContact CD2-CE 3.56Å; F216-M219 HydrophobicContact CE2-CE 3.62Å; F216-M219 HydrophobicContact CG-CE 4.47Å; F216-M219 PolarHBondContact O-N 3.21Å; M219-N222 PolarHBondContact O-N 3.39Å; M219-L223 PolarHBondContact O-N 2.9Å; M219-A241 HydrophobicContact CB-CB 4.02Å; M219-R242 HydrophobicContact CG-CB 4.44Å; M219-R242 HydrophobicContact SD-CB 4.1Å; M219-R242 HydrophobicContact SD-CG 4.42Å; M219-I245 HydrophobicContact CB-CD1 4.14Å; M219-I245 HydrophobicContact CE-CD1 4.01Å; M219-I245 HydrophobicContact SD-CD1 3.76Å; M219-T297 HydrophobicContact CE-CG2 3.87Å; M219-T297 HydrophobicContact SD-CG2 3.86Å
220T90.3Very high89.5Confident18 Ų1858 Ų5811%0.1129%0.289CS..Hα-helixtrans-65.6-40.9-176.550.40000112.8F216 E217 N222 L223 F301F216-T220 HydrophobicContact CD1-CG2 4.15Å; F216-T220 HydrophobicContact CE1-CG2 3.78Å; F216-T220 HydrophobicContact CZ-CG2 4.02Å; F216-T220 WeakPolarHBondContact O-CB 3.29Å; F216-T220 WeakPolarHBondContact O-CG2 3.29Å; F216-T220 PolarHBondContact O-N 2.83Å; F216-T220 PolarHBondContact O-OG1 2.93Å; E217-T220 WeakPolarHBondContact CA-OG1 3.26Å; E217-T220 PolarHBondContact O-N 2.91Å; E217-T220 PolarHBondContact O-OG1 3.44Å; T220-N222 PolarHBondContact O-N 3.46Å; T220-L223 HydrophobicContact CG2-CD1 4.49Å; T220-L223 PolarHBondContact O-N 3.45Å; T220-F301 HydrophobicContact CG2-CD2 3.89Å; T220-F301 HydrophobicContact CG2-CE2 4.19Å
221R90.2Very high90.1Very high175 Ų17558.9 Ų58.966%0.6630%0.301SS*.Hα-helixtrans-56.8-33.5175.2-175.7-174.2-62169-4.7112.6E217 E218E217-R221 WeakPolarHBondContact O-CB 3.28Å; E217-R221 PolarHBondContact O-N 3.36Å; E218-R221 IonicContact OE2-CZ 2.72Å; E218-R221 IonicContact OE2-NH1 3.59Å; E218-R221 PolarHBondContact OE2-NH1 2.86Å
222N93.2Very high90.4Very high18 Ų1861.7 Ų61.710%0.09631%0.312CS..Hα-helixtrans-97.1-2.1-174.1-73.2-63.2000114.6I119 E218 M219 T220 F224 S225 G234I119-N222 HydrophobicContact CD1-CB 4.3Å; I119-N222 WeakPolarHBondContact CD1-O 3.24Å; E218-N222 PolarHBondContact O-N 2.93Å; E218-N222 PolarHBondContact O-ND2 3.35Å; E218-N222 PolarHBondContact OE1-ND2 2.93Å; M219-N222 PolarHBondContact O-N 3.39Å; T220-N222 PolarHBondContact O-N 3.46Å; N222-F224 PolarHBondContact O-N 3.45Å; N222-F224 VanDerWaalsContact O-N 3.1Å; N222-S225 VanDerWaalsContact O-CB 3.27Å; N222-S225 WeakPolarHBondContact O-CB 3.03Å; N222-S225 PolarHBondContact O-N 2.89Å; N222-S225 PolarHBondContact O-OG 2.91Å; N222-G234 WeakPolarHBondContact CB-O 2.95Å; N222-G234 WeakPolarHBondContact OD1-CA 3.36Å; N222-G234 PolarHBondContact OD1-O 2.97Å
223L90.2Very high90.8Very high2 Ų261.8 Ų61.81%0.0131%0.314CS..THydrogen-bonded Turntrans-52.4-37.4-178.7-79.4173.4000113.9S115 V116 I119 L120 M219 T220 F301S115-L223 CarbonylContact C-O 3.54Å; S115-L223 WeakPolarHBondContact CB-O 3.45Å; S115-L223 PolarHBondContact OG-O 3.14Å; V116-L223 WeakPolarHBondContact CA-O 3.3Å; V116-L223 HydrophobicContact CG1-CD2 4.48Å; V116-L223 HydrophobicContact CG2-CB 4.28Å; V116-L223 WeakPolarHBondContact CG2-O 3.3Å; V116-L223 PolarHBondContact N-O 2.89Å; I119-L223 HydrophobicContact CB-CD2 3.95Å; I119-L223 HydrophobicContact CG2-CD2 3.66Å; L120-L223 HydrophobicContact CD1-CD2 4.33Å; L120-L223 HydrophobicContact CD2-CD2 3.81Å; L120-L223 HydrophobicContact CG-CD2 3.67Å; M219-L223 PolarHBondContact O-N 2.9Å; T220-L223 HydrophobicContact CG2-CD1 4.49Å; T220-L223 PolarHBondContact O-N 3.45Å; L223-F301 HydrophobicContact CD1-CD2 3.85Å; L223-F301 HydrophobicContact CD1-CE1 4.43Å; L223-F301 HydrophobicContact CD1-CE2 3.23Å; L223-F301 HydrophobicContact CD1-CZ 3.57Å
224F87.8Confident91.3Very high95 Ų9561.9 Ų61.942%0.41732%0.319SS..THydrogen-bonded Turntrans-10322.5-178.4-64-89.4000113.3W112 P113 V116 N222 P480W112-F224 HydrophobicContact CZ3-CE1 4.34Å; W112-F224 AromaticContact CZ3-CZ 3.98Å; W112-F224 HydrophobicContact CZ3-CZ 3.98Å; P113-F224 HydrophobicContact CG-CD1 4.02Å; P113-F224 HydrophobicContact CG-CE1 4.2Å; V116-F224 HydrophobicContact CG2-CD1 4.03Å; V116-F224 HydrophobicContact CG2-CE1 3.96Å; V116-F224 HydrophobicContact CG2-CG 4.38Å; V116-F224 HydrophobicContact CG2-CZ 4.25Å; N222-F224 PolarHBondContact O-N 3.45Å; N222-F224 VanDerWaalsContact O-N 3.1Å; F224-P480 HydrophobicContact CE2-CB 3.92Å; F224-P480 HydrophobicContact CE2-CG 4.39Å
225S90.7Very high91.6Very high24 Ų2457.3 Ų57.317%0.16830%0.297CS..SBendtrans-65166.7176.273.70000112.1S115 N222 L235S115-S225 WeakPolarHBondContact CB-O 3.45Å; S115-S225 PolarHBondContact OG-O 3.45Å; N222-S225 VanDerWaalsContact O-CB 3.27Å; N222-S225 WeakPolarHBondContact O-CB 3.03Å; N222-S225 PolarHBondContact O-N 2.89Å; N222-S225 PolarHBondContact O-OG 2.91Å; S225-L235 WeakPolarHBondContact OG-CA 3.39Å; S225-L235 PolarHBondContact OG-N 2.99Å; S225-L235 VanDerWaalsContact OG-N 3.13Å
226L89.3Confident91.8Very high128 Ų12861.2 Ų61.267%0.6731%0.311SS*.  trans-61.7144.9166.6-66.2176.7000110.1I228L226-I228 HydrophobicContact CB-CD1 4.11Å; L226-I228 HydrophobicContact CB-CG1 4.23Å; L226-I228 HydrophobicContact CD1-CD1 4.23Å; L226-I228 PolarHBondContact O-N 3.45Å
227P88.3Confident92.1Very high83 Ų8367.3 Ų67.354%0.53933%0.334SS..SBendtrans-80.855.8-177.935.5-37.2000111.4A114A114-P227 HydrophobicContact CB-CB 3.97Å
228I91.6Very high92.4Very high92 Ų9264.2 Ų64.247%0.47232%0.319SS..  trans-120116.1-179.1-57.4171.6000106.6L226 V230 S233 L235L226-I228 HydrophobicContact CB-CD1 4.11Å; L226-I228 HydrophobicContact CB-CG1 4.23Å; L226-I228 HydrophobicContact CD1-CD1 4.23Å; L226-I228 PolarHBondContact O-N 3.45Å; I228-V230 HydrophobicContact CG2-CG1 4.23Å; I228-V230 HydrophobicContact CG2-CG2 4.09Å; I228-S233 WeakPolarHBondContact O-CB 3.48Å; I228-S233 PolarHBondContact O-OG 2.9Å; I228-L235 WeakPolarHBondContact O-CB 3.29Å
229D91.9Very high92.5Very high101 Ų10163.2 Ų63.254%0.5432%0.316SS..  trans-99.691-176.8-16811000110.7L235D229-L235 HydrophobicContact CB-CD2 4Å
230V93.9Very high92.6Very high50 Ų5069.8 Ų69.830%0.30335%0.345SS..SBendtrans-140.2153.4177.2-64.90000109I228 F232 S233 Y236I228-V230 HydrophobicContact CG2-CG1 4.23Å; I228-V230 HydrophobicContact CG2-CG2 4.09Å; V230-F232 HydrophobicContact CB-CE1 4.35Å; V230-F232 HydrophobicContact CB-CZ 4.32Å; V230-F232 HydrophobicContact CG2-CD1 4.43Å; V230-F232 HydrophobicContact CG2-CD2 4.09Å; V230-F232 HydrophobicContact CG2-CE1 4.02Å; V230-F232 HydrophobicContact CG2-CE2 3.65Å; V230-F232 HydrophobicContact CG2-CG 4.46Å; V230-F232 HydrophobicContact CG2-CZ 3.61Å; V230-F232 PolarHBondContact O-N 3.02Å; V230-S233 PolarHBondContact N-OG 2.98Å; V230-S233 WeakPolarHBondContact O-CB 3.37Å; V230-S233 PolarHBondContact O-N 3.05Å; V230-S233 PolarHBondContact O-OG 3.47Å; V230-Y236 WeakPolarHBondContact O-CB 3.36Å
231P90.6Very high92.9Very high94 Ų9469.3 Ų69.361%0.6134%0.343SS*.THydrogen-bonded Turntrans-53.9-19.9-166.1-31.336.8000118Y236P231-Y236 HydrophobicContact CB-CE1 4.43Å; P231-Y236 WeakPolarHBondContact O-CD1 3.23Å; P231-Y236 WeakPolarHBondContact O-CE1 3.46Å
232F90.7Very high93.1Very high159 Ų15963.1 Ų63.170%0.69732%0.319SS*.THydrogen-bonded Turntrans-108.2-2.9178.952.1-94.6000113.8V230V230-F232 HydrophobicContact CB-CE1 4.35Å; V230-F232 HydrophobicContact CB-CZ 4.32Å; V230-F232 HydrophobicContact CG2-CD1 4.43Å; V230-F232 HydrophobicContact CG2-CD2 4.09Å; V230-F232 HydrophobicContact CG2-CE1 4.02Å; V230-F232 HydrophobicContact CG2-CE2 3.65Å; V230-F232 HydrophobicContact CG2-CG 4.46Å; V230-F232 HydrophobicContact CG2-CZ 3.61Å; V230-F232 PolarHBondContact O-N 3.02Å
233S95.2Very high93.2Very high16 Ų1666 Ų6611%0.11234%0.335CS..SBendtrans-76.5156.318076.70000111.9I228 V230 L235 Y236 R237I228-S233 WeakPolarHBondContact O-CB 3.48Å; I228-S233 PolarHBondContact O-OG 2.9Å; V230-S233 PolarHBondContact N-OG 2.98Å; V230-S233 WeakPolarHBondContact O-CB 3.37Å; V230-S233 PolarHBondContact O-N 3.05Å; V230-S233 PolarHBondContact O-OG 3.47Å; S233-L235 VanDerWaalsContact C-N 3.28Å; S233-L235 PolarHBondContact O-N 3.02Å; S233-Y236 PolarHBondContact O-N 3.45Å; S233-Y236 PolarHBondContact OG-N 3.05Å; S233-R237 WeakPolarHBondContact O-CG 3.31Å; S233-R237 PolarHBondContact O-N 2.85Å
234G95.1Very high93.4Very high19 Ų1969.3 Ų69.320%0.19635%0.352CS..Hα-helixtrans-60.7-37.7173.600000112.7N222 Y236 R237 G238N222-G234 WeakPolarHBondContact CB-O 2.95Å; N222-G234 WeakPolarHBondContact OD1-CA 3.36Å; N222-G234 PolarHBondContact OD1-O 2.97Å; G234-Y236 PolarHBondContact O-N 2.77Å; G234-R237 PolarHBondContact O-N 3.19Å; G234-G238 PolarHBondContact O-N 3.46Å
235L95.6Very high93.6Very high10 Ų1065 Ų655%0.05233%0.333CS..Hα-helixtrans-61.9-45.9179.5-179.361.4000111.2T118 I119 S225 I228 D229 S233 R237 G238 V239T118-L235 HydrophobicContact CG2-CD1 4.02Å; I119-L235 HydrophobicContact CD1-CD1 3.92Å; I119-L235 HydrophobicContact CG1-CD1 3.76Å; S225-L235 WeakPolarHBondContact OG-CA 3.39Å; S225-L235 PolarHBondContact OG-N 2.99Å; S225-L235 VanDerWaalsContact OG-N 3.13Å; I228-L235 WeakPolarHBondContact O-CB 3.29Å; D229-L235 HydrophobicContact CB-CD2 4Å; S233-L235 VanDerWaalsContact C-N 3.28Å; S233-L235 PolarHBondContact O-N 3.02Å; L235-R237 PolarHBondContact O-N 3.04Å; L235-G238 PolarHBondContact O-N 2.87Å; L235-V239 HydrophobicContact CD1-CG2 4.15Å; L235-V239 HydrophobicContact CG-CG2 4.47Å; L235-V239 WeakPolarHBondContact O-CB 3.48Å; L235-V239 VanDerWaalsContact O-CG2 3.32Å; L235-V239 WeakPolarHBondContact O-CG2 3.35Å; L235-V239 PolarHBondContact O-N 3.34Å
236Y96Very high93.7Very high91 Ų9164.3 Ų64.336%0.35733%0.327SS..Hα-helixtrans-60.2-47.5177.7176.1-93.2000111.5V230 P231 S233 G234 G238 V239 K240V230-Y236 WeakPolarHBondContact O-CB 3.36Å; P231-Y236 HydrophobicContact CB-CE1 4.43Å; P231-Y236 WeakPolarHBondContact O-CD1 3.23Å; P231-Y236 WeakPolarHBondContact O-CE1 3.46Å; S233-Y236 PolarHBondContact O-N 3.45Å; S233-Y236 PolarHBondContact OG-N 3.05Å; G234-Y236 PolarHBondContact O-N 2.77Å; Y236-G238 PolarHBondContact O-N 2.91Å; Y236-V239 PolarHBondContact O-N 3.29Å; Y236-K240 HydrophobicContact CE1-CD 4.41Å; Y236-K240 WeakPolarHBondContact O-CB 3.28Å; Y236-K240 PolarHBondContact O-N 2.99Å
237R96.7Very high93.9Very high131 Ų13160.5 Ų60.549%0.49431%0.314SS..Hα-helixtrans-61.1-44.5177.9-67.2179.6-175.6-172.1-0.1111.9E218 S233 G234 L235 K240 A241E218-R237 HydrophobicContact CG-CB 4.43Å; E218-R237 WeakPolarHBondContact OE1-CB 3.41Å; E218-R237 WeakPolarHBondContact OE1-CD 3.46Å; S233-R237 WeakPolarHBondContact O-CG 3.31Å; S233-R237 PolarHBondContact O-N 2.85Å; G234-R237 PolarHBondContact O-N 3.19Å; L235-R237 PolarHBondContact O-N 3.04Å; R237-K240 PolarHBondContact O-N 3.43Å; R237-A241 WeakPolarHBondContact O-CB 3.34Å; R237-A241 PolarHBondContact O-N 2.84Å
238G96.3Very high93.9Very high0 Ų058.6 Ų58.60%030%0.296CS..Hα-helixtrans-63.4-41.5177.200000113G234 L235 Y236 R242G234-G238 PolarHBondContact O-N 3.46Å; L235-G238 PolarHBondContact O-N 2.87Å; Y236-G238 PolarHBondContact O-N 2.91Å; G238-R242 WeakPolarHBondContact O-CB 3.36Å; G238-R242 PolarHBondContact O-N 3.43Å
239V95.7Very high93.9Very high22 Ų2254.4 Ų54.413%0.13328%0.275CS..Hα-helixtrans-67.6-41175.8168.60000111.6T118 I119 L235 Y236 R242 N243T118-V239 HydrophobicContact CG2-CG2 3.96Å; I119-V239 HydrophobicContact CG1-CG2 4.18Å; L235-V239 HydrophobicContact CD1-CG2 4.15Å; L235-V239 HydrophobicContact CG-CG2 4.47Å; L235-V239 WeakPolarHBondContact O-CB 3.48Å; L235-V239 VanDerWaalsContact O-CG2 3.32Å; L235-V239 WeakPolarHBondContact O-CG2 3.35Å; L235-V239 PolarHBondContact O-N 3.34Å; Y236-V239 PolarHBondContact O-N 3.29Å; V239-R242 WeakPolarHBondContact O-CB 3.1Å; V239-R242 PolarHBondContact O-N 2.62Å; V239-N243 PolarHBondContact O-N 3.05Å; V239-N243 PolarHBondContact O-ND2 3.38Å; V239-N243 PolarHBondContact O-OD1 3.11Å
240K96.1Very high94Very high138 Ų13851.6 Ų51.660%0.626%0.258SS*.Hα-helixtrans-60.3-47.5175.4-175.4-178.1177.9-175.50111Y236 R237 N243 L244Y236-K240 HydrophobicContact CE1-CD 4.41Å; Y236-K240 WeakPolarHBondContact O-CB 3.28Å; Y236-K240 PolarHBondContact O-N 2.99Å; R237-K240 PolarHBondContact O-N 3.43Å; K240-N243 PolarHBondContact O-N 3.45Å; K240-L244 PolarHBondContact O-N 2.6Å
241A95.8Very high93.8Very high8 Ų854 Ų547%0.06627%0.266CS..Hα-helixtrans-60.3-46.2175.900000112.5A215 E218 M219 R237 N243 L244 I245A215-A241 WeakPolarHBondContact O-CB 3.07Å; E218-A241 HydrophobicContact CB-CB 4.19Å; E218-A241 HydrophobicContact CG-CB 4.36Å; M219-A241 HydrophobicContact CB-CB 4.02Å; R237-A241 WeakPolarHBondContact O-CB 3.34Å; R237-A241 PolarHBondContact O-N 2.84Å; A241-N243 VanDerWaalsContact C-N 3.29Å; A241-N243 PolarHBondContact O-N 3.44Å; A241-L244 WeakPolarHBondContact O-CB 3.35Å; A241-L244 PolarHBondContact O-N 2.81Å; A241-I245 WeakPolarHBondContact O-CG1 3.48Å; A241-I245 PolarHBondContact O-N 2.88Å; A241-I245 VanDerWaalsContact O-N 3.14Å
242R94.9Very high93.7Very high45 Ų4550 Ų5017%0.1724%0.24CC..Hα-helixtrans-54.6-44.6173.3179.2-155.173.8-172.5-1.9112.1T118 I119 M219 G238 V239 L244 I245 H246T118-R242 PolarHBondContact O-NH1 3.18Å; I119-R242 WeakPolarHBondContact O-CD 3.25Å; I119-R242 WeakPolarHBondContact O-CG 3.37Å; M219-R242 HydrophobicContact CG-CB 4.44Å; M219-R242 HydrophobicContact SD-CB 4.1Å; M219-R242 HydrophobicContact SD-CG 4.42Å; G238-R242 WeakPolarHBondContact O-CB 3.36Å; G238-R242 PolarHBondContact O-N 3.43Å; V239-R242 WeakPolarHBondContact O-CB 3.1Å; V239-R242 PolarHBondContact O-N 2.62Å; R242-L244 VanDerWaalsContact C-N 3.29Å; R242-L244 PolarHBondContact O-N 2.88Å; R242-I245 PolarHBondContact O-N 3.34Å; R242-H246 WeakPolarHBondContact O-CB 3.42Å; R242-H246 PolarHBondContact O-CD2 2.91Å; R242-H246 PolarHBondContact O-N 2.77Å
243N95.1Very high93.7Very high79 Ų7942.4 Ų42.442%0.42221%0.206SC..Hα-helixtrans-63.8-36.3-177.8-68.3-15.2000112.2V239 K240 A241 H246 A247V239-N243 PolarHBondContact O-N 3.05Å; V239-N243 PolarHBondContact O-ND2 3.38Å; V239-N243 PolarHBondContact O-OD1 3.11Å; K240-N243 PolarHBondContact O-N 3.45Å; A241-N243 VanDerWaalsContact C-N 3.29Å; A241-N243 PolarHBondContact O-N 3.44Å; N243-H246 PolarHBondContact O-N 2.68Å; N243-A247 PolarHBondContact O-N 3.29Å
244L93.6Very high93.6Very high70 Ų7048 Ų4837%0.36623%0.225SC..Hα-helixtrans-63.8-47.9173.7178.860.3000111.4Q211 A215 K240 A241 R242 H246 A247 R248Q211-L244 HydrophobicContact CG-CD2 4.09Å; A215-L244 HydrophobicContact CB-CD2 3.8Å; A215-L244 HydrophobicContact CB-CG 4.38Å; K240-L244 PolarHBondContact O-N 2.6Å; A241-L244 WeakPolarHBondContact O-CB 3.35Å; A241-L244 PolarHBondContact O-N 2.81Å; R242-L244 VanDerWaalsContact C-N 3.29Å; R242-L244 PolarHBondContact O-N 2.88Å; L244-H246 VanDerWaalsContact C-N 3.34Å; L244-H246 PolarHBondContact O-N 2.65Å; L244-A247 WeakPolarHBondContact O-CB 3.29Å; L244-A247 PolarHBondContact O-N 3.36Å; L244-R248 PolarHBondContact O-N 2.97Å
245I92.3Very high93.2Very high6 Ų647.9 Ų47.93%0.03122%0.222CC..Hα-helixtrans-60-45.3176.4-62.4161.7000110.6A215 F216 M219 A241 R242 A247 R248 I249A215-I245 HydrophobicContact CB-CD1 4.33Å; A215-I245 HydrophobicContact CB-CG1 3.99Å; F216-I245 HydrophobicContact CB-CD1 4.16Å; F216-I245 HydrophobicContact CD2-CD1 4.2Å; M219-I245 HydrophobicContact CB-CD1 4.14Å; M219-I245 HydrophobicContact CE-CD1 4.01Å; M219-I245 HydrophobicContact SD-CD1 3.76Å; A241-I245 WeakPolarHBondContact O-CG1 3.48Å; A241-I245 PolarHBondContact O-N 2.88Å; A241-I245 VanDerWaalsContact O-N 3.14Å; R242-I245 PolarHBondContact O-N 3.34Å; I245-A247 VanDerWaalsContact C-N 3.32Å; I245-A247 PolarHBondContact O-N 2.6Å; I245-R248 PolarHBondContact O-N 2.9Å; I245-I249 HydrophobicContact CG2-CD1 3.61Å; I245-I249 HydrophobicContact CG2-CG1 4.29Å; I245-I249 WeakPolarHBondContact O-CG1 3.38Å; I245-I249 PolarHBondContact O-N 2.81Å
246H94Very high92.9Very high9 Ų948.2 Ų48.24%0.04222%0.223CC..Hα-helixtrans-61.2-38.4178.4-83-159.1000112.6R242 N243 L244 R248 I249 E250 K293 T297R242-H246 WeakPolarHBondContact O-CB 3.42Å; R242-H246 PolarHBondContact O-CD2 2.91Å; R242-H246 PolarHBondContact O-N 2.77Å; N243-H246 PolarHBondContact O-N 2.68Å; L244-H246 VanDerWaalsContact C-N 3.34Å; L244-H246 PolarHBondContact O-N 2.65Å; H246-R248 VanDerWaalsContact C-N 3.33Å; H246-I249 PolarHBondContact O-N 2.05Å; H246-E250 VanDerWaalsContact O-CB 3.28Å; H246-E250 WeakPolarHBondContact O-CB 3.46Å; H246-E250 PolarHBondContact O-N 3.3Å; H246-K293 HydrophobicContact CB-CD 4.08Å; H246-K293 WeakPolarHBondContact O-CD 3.34Å; H246-T297 PolarHBondContact CD2-OG1 3.28Å; H246-T297 VanDerWaalsContact CD2-OG1 3.28Å; H246-T297 PolarHBondContact NE2-OG1 2.96Å
247A92.4Very high92.5Very high47 Ų4746.5 Ų46.539%0.38822%0.22SC..Hα-helixtrans-61.1-44.7176.300000110.9N243 L244 I245 E250 E251N243-A247 PolarHBondContact O-N 3.29Å; L244-A247 WeakPolarHBondContact O-CB 3.29Å; L244-A247 PolarHBondContact O-N 3.36Å; I245-A247 VanDerWaalsContact C-N 3.32Å; I245-A247 PolarHBondContact O-N 2.6Å; A247-E250 WeakPolarHBondContact O-CB 3.23Å; A247-E250 PolarHBondContact O-N 2.84Å; A247-E251 PolarHBondContact O-N 3.36Å; A247-E251 VanDerWaalsContact O-N 3.14Å
248R88.7Confident92Very high43 Ų4348.6 Ų48.616%0.16223%0.228CC..Hα-helixtrans-68-43.1178.8-168.560.1167.8156.8-11113.2A201 A202 S203 L212 L244 I245 H246 E250 E251 N252A201-R248 PolarHBondContact O-NH1 3.01Å; A201-R248 PolarHBondContact O-NH2 3.43Å; A202-R248 PolarHBondContact O-NE 3.3Å; A202-R248 PolarHBondContact O-NH2 3.28Å; S203-R248 PolarHBondContact O-NH2 3.49Å; L212-R248 HydrophobicContact CD1-CG 3.93Å; L212-R248 HydrophobicContact CD2-CB 3.81Å; L212-R248 HydrophobicContact CD2-CG 3.97Å; L244-R248 PolarHBondContact O-N 2.97Å; I245-R248 PolarHBondContact O-N 2.9Å; H246-R248 VanDerWaalsContact C-N 3.33Å; R248-E250 PolarHBondContact O-N 3.04Å; R248-E251 IonicContact CZ-OE2 3.82Å; R248-E251 IonicContact NH1-OE2 2.75Å; R248-E251 PolarHBondContact NH1-OE2 3.31Å; R248-E251 PolarHBondContact O-N 3.23Å; R248-N252 PolarHBondContact O-N 3.42Å; R248-N252 VanDerWaalsContact O-N 3.14Å
249I91.3Very high91.4Very high5 Ų556.6 Ų56.63%0.02626%0.258CS..Hα-helixtrans-60.5-39.5175-68.1171.3000110.1L194 I245 H246 E251 N252 I253 K293 T297 L300L194-I249 HydrophobicContact CD1-CD1 4.4Å; L194-I249 HydrophobicContact CD1-CG1 4.01Å; I245-I249 HydrophobicContact CG2-CD1 3.61Å; I245-I249 HydrophobicContact CG2-CG1 4.29Å; I245-I249 WeakPolarHBondContact O-CG1 3.38Å; I245-I249 PolarHBondContact O-N 2.81Å; H246-I249 PolarHBondContact O-N 2.05Å; I249-E251 PolarHBondContact O-N 3.1Å; I249-N252 PolarHBondContact O-N 3.27Å; I249-I253 HydrophobicContact CG2-CD1 3.6Å; I249-I253 HydrophobicContact CG2-CG1 4.11Å; I249-I253 VanDerWaalsContact O-CG1 3.23Å; I249-I253 WeakPolarHBondContact O-CG1 3.38Å; I249-I253 PolarHBondContact O-N 3.33Å; I249-K293 HydrophobicContact CG2-CB 4.47Å; I249-K293 HydrophobicContact CG2-CG 4.06Å; I249-T297 WeakPolarHBondContact CD1-OG1 3.21Å; I249-L300 HydrophobicContact CD1-CD1 4.46Å
250E93.3Very high90.5Very high42 Ų4258 Ų5820%0.19626%0.264CS..Hα-helixtrans-60.9-45.2177.9-172.2156.3159.200112.6H246 A247 R248 N252 I253 R254 M289 K293H246-E250 VanDerWaalsContact O-CB 3.28Å; H246-E250 WeakPolarHBondContact O-CB 3.46Å; H246-E250 PolarHBondContact O-N 3.3Å; A247-E250 WeakPolarHBondContact O-CB 3.23Å; A247-E250 PolarHBondContact O-N 2.84Å; R248-E250 PolarHBondContact O-N 3.04Å; E250-N252 VanDerWaalsContact C-N 3.31Å; E250-N252 PolarHBondContact O-N 3.04Å; E250-I253 PolarHBondContact O-N 3.5Å; E250-R254 WeakPolarHBondContact O-CB 3.01Å; E250-R254 VanDerWaalsContact O-CG 3.28Å; E250-R254 WeakPolarHBondContact O-CG 3.47Å; E250-R254 PolarHBondContact O-N 3.33Å; E250-R254 IonicContact OE1-CZ 3.32Å; E250-R254 IonicContact OE1-NE 3.92Å; E250-R254 PolarHBondContact OE1-NE 3.17Å; E250-R254 IonicContact OE1-NH2 3.53Å; E250-R254 PolarHBondContact OE1-NH2 3.45Å; E250-M289 HydrophobicContact CB-SD 4.42Å; E250-M289 HydrophobicContact CG-CE 4.08Å; E250-M289 HydrophobicContact CG-CG 4.14Å; E250-M289 HydrophobicContact CG-SD 3.77Å; E250-K293 HydrophobicContact CB-CD 3.92Å; E250-K293 HydrophobicContact CG-CD 4.47Å; E250-K293 IonicContact OE2-NZ 2.85Å; E250-K293 PolarHBondContact OE2-NZ 3.44Å
251E90.1Very high88.9Confident101 Ų10155.4 Ų55.447%0.47228%0.277SS..Hα-helixtrans-59-44.9176.1-70.9171.8178.300111.6A247 R248 I249 R254 A255A247-E251 PolarHBondContact O-N 3.36Å; A247-E251 VanDerWaalsContact O-N 3.14Å; R248-E251 IonicContact CZ-OE2 3.82Å; R248-E251 IonicContact NH1-OE2 2.75Å; R248-E251 PolarHBondContact NH1-OE2 3.31Å; R248-E251 PolarHBondContact O-N 3.23Å; I249-E251 PolarHBondContact O-N 3.1Å; E251-R254 PolarHBondContact O-N 2.87Å; E251-A255 WeakPolarHBondContact O-CB 3.44Å; E251-A255 PolarHBondContact O-N 3.24Å
252N89.6Confident87.6Confident9 Ų960.1 Ų60.15%0.04831%0.305CS..Hα-helixtrans-65.1-45.2177.7-173.414.4000111.9L194 C196 R248 I249 E250 R254 A255 K256L194-N252 PolarHBondContact O-ND2 3.47Å; C196-N252 PolarHBondContact SG-ND2 3.4Å; C196-N252 VanDerWaalsContact SG-ND2 3.38Å; R248-N252 PolarHBondContact O-N 3.42Å; R248-N252 VanDerWaalsContact O-N 3.14Å; I249-N252 PolarHBondContact O-N 3.27Å; E250-N252 VanDerWaalsContact C-N 3.31Å; E250-N252 PolarHBondContact O-N 3.04Å; N252-R254 VanDerWaalsContact C-N 3.33Å; N252-R254 PolarHBondContact O-N 3.16Å; N252-A255 WeakPolarHBondContact O-CB 3.18Å; N252-A255 PolarHBondContact O-N 3.25Å; N252-A255 VanDerWaalsContact O-N 3.14Å; N252-K256 WeakPolarHBondContact O-CG 3.21Å; N252-K256 PolarHBondContact O-N 2.85Å; N252-K256 WeakPolarHBondContact OD1-CE 2.99Å
253I91.1Very high85.7Confident0 Ų067.3 Ų67.30%034%0.341CS..Hα-helixtrans-56.4-49.2173.8-68.5163.4000110I249 E250 A255 K256 I257 L273 I277 M289 L292 K293I249-I253 HydrophobicContact CG2-CD1 3.6Å; I249-I253 HydrophobicContact CG2-CG1 4.11Å; I249-I253 VanDerWaalsContact O-CG1 3.23Å; I249-I253 WeakPolarHBondContact O-CG1 3.38Å; I249-I253 PolarHBondContact O-N 3.33Å; E250-I253 PolarHBondContact O-N 3.5Å; I253-A255 VanDerWaalsContact C-N 3.28Å; I253-A255 PolarHBondContact O-N 2.97Å; I253-K256 PolarHBondContact O-N 2.92Å; I253-I257 HydrophobicContact CG2-CD1 3.63Å; I253-I257 HydrophobicContact CG2-CG1 4.15Å; I253-I257 WeakPolarHBondContact O-CB 3.27Å; I253-I257 VanDerWaalsContact O-CG1 3.26Å; I253-I257 WeakPolarHBondContact O-CG1 3.46Å; I253-I257 PolarHBondContact O-N 2.58Å; I253-L273 HydrophobicContact CG1-CD1 4.15Å; I253-L273 HydrophobicContact CG1-CD2 3.9Å; I253-L273 HydrophobicContact CG1-CG 4.46Å; I253-I277 HydrophobicContact CG2-CD1 4.29Å; I253-M289 HydrophobicContact CB-CE 4.23Å; I253-M289 HydrophobicContact CB-SD 4Å; I253-M289 HydrophobicContact CD1-SD 3.74Å; I253-M289 HydrophobicContact CG1-SD 4.49Å; I253-M289 HydrophobicContact CG2-CE 3.68Å; I253-M289 HydrophobicContact CG2-SD 3.74Å; I253-L292 HydrophobicContact CD1-CB 3.58Å; I253-L292 HydrophobicContact CG1-CB 4.43Å; I253-L292 HydrophobicContact CG2-CD1 3.86Å; I253-K293 HydrophobicContact CD1-CG 3.9Å
254R91.4Very high84Confident132 Ų13267.1 Ų67.150%0.49834%0.337SS..Hα-helixtrans-60.7-38.9179-70.8175.4-176.9-167.11.4111.6E250 E251 N252 R258 M289E250-R254 WeakPolarHBondContact O-CB 3.01Å; E250-R254 VanDerWaalsContact O-CG 3.28Å; E250-R254 WeakPolarHBondContact O-CG 3.47Å; E250-R254 PolarHBondContact O-N 3.33Å; E250-R254 IonicContact OE1-CZ 3.32Å; E250-R254 IonicContact OE1-NE 3.92Å; E250-R254 PolarHBondContact OE1-NE 3.17Å; E250-R254 IonicContact OE1-NH2 3.53Å; E250-R254 PolarHBondContact OE1-NH2 3.45Å; E251-R254 PolarHBondContact O-N 2.87Å; N252-R254 VanDerWaalsContact C-N 3.33Å; N252-R254 PolarHBondContact O-N 3.16Å; R254-R258 WeakPolarHBondContact O-CG 3.42Å; R254-R258 PolarHBondContact O-N 2.88Å; R254-R258 VanDerWaalsContact O-N 3.09Å; R254-R258 PolarHBondContact O-NH1 2.92Å; R254-M289 HydrophobicContact CG-CE 3.84Å
255A87.9Confident82.2Confident17 Ų1768.4 Ų68.414%0.1435%0.349CS..Hα-helixtrans-64-45.417600000112.1E251 N252 I253 R258 R259E251-A255 WeakPolarHBondContact O-CB 3.44Å; E251-A255 PolarHBondContact O-N 3.24Å; N252-A255 WeakPolarHBondContact O-CB 3.18Å; N252-A255 PolarHBondContact O-N 3.25Å; N252-A255 VanDerWaalsContact O-N 3.14Å; I253-A255 VanDerWaalsContact C-N 3.28Å; I253-A255 PolarHBondContact O-N 2.97Å; A255-R258 PolarHBondContact O-N 3.03Å; A255-R259 WeakPolarHBondContact O-CG 3.26Å; A255-R259 PolarHBondContact O-N 2.84Å
256K88.4Confident79.9Confident17 Ų1778.1 Ų78.17%0.07440%0.395CS..Hα-helixtrans-61.5-46.9174.9-69.4-178.8-174.9-65.50111.5L194 N252 I253 R258 R259 L260 D271 L273 Q274 I277L194-K256 WeakPolarHBondContact O-CE 3.5Å; L194-K256 PolarHBondContact O-NZ 2.91Å; N252-K256 WeakPolarHBondContact O-CG 3.21Å; N252-K256 PolarHBondContact O-N 2.85Å; N252-K256 WeakPolarHBondContact OD1-CE 2.99Å; I253-K256 PolarHBondContact O-N 2.92Å; K256-R258 VanDerWaalsContact C-N 3.28Å; K256-R258 PolarHBondContact O-N 3.2Å; K256-R259 WeakPolarHBondContact O-CB 3.33Å; K256-R259 PolarHBondContact O-N 3.23Å; K256-L260 WeakPolarHBondContact O-CG 3.37Å; K256-L260 PolarHBondContact O-N 2.92Å; K256-L260 VanDerWaalsContact O-N 3.13Å; K256-D271 VanDerWaalsContact NZ-CG 3.32Å; K256-D271 IonicContact NZ-OD1 2.78Å; K256-D271 PolarHBondContact NZ-OD1 2.87Å; K256-D271 IonicContact NZ-OD2 3.03Å; K256-D271 PolarHBondContact NZ-OD2 3.34Å; K256-L273 HydrophobicContact CD-CD2 4.12Å; K256-L273 HydrophobicContact CD-CG 4.09Å; K256-Q274 HydrophobicContact CD-CB 4.43Å; K256-I277 HydrophobicContact CB-CD1 4.09Å; K256-I277 HydrophobicContact CD-CD1 4.27Å
257I87.8Confident78.1Confident55 Ų5581.4 Ų81.428%0.28243%0.431SS..Hα-helixtrans-57.7-39.4178-68.3178000112.3I253 R259 L260 I277 W281I253-I257 HydrophobicContact CG2-CD1 3.63Å; I253-I257 HydrophobicContact CG2-CG1 4.15Å; I253-I257 WeakPolarHBondContact O-CB 3.27Å; I253-I257 VanDerWaalsContact O-CG1 3.26Å; I253-I257 WeakPolarHBondContact O-CG1 3.46Å; I253-I257 PolarHBondContact O-N 2.58Å; I257-R259 VanDerWaalsContact C-N 3.25Å; I257-R259 PolarHBondContact O-N 3.48Å; I257-L260 PolarHBondContact O-N 2.99Å; I257-I277 HydrophobicContact CG1-CG2 4.41Å; I257-W281 HydrophobicContact CB-CH2 4.26Å; I257-W281 HydrophobicContact CD1-CH2 4.15Å; I257-W281 HydrophobicContact CD1-CZ2 4.01Å; I257-W281 HydrophobicContact CG1-CH2 3.69Å; I257-W281 HydrophobicContact CG1-CZ2 4.02Å; I257-W281 HydrophobicContact CG2-CH2 3.96Å
258R86.8Confident77Confident176 Ų17684.4 Ų84.466%0.66444%0.441SS*.Hα-helixtrans-67.5-24.2176.8-74.6-171.9-60.6-92.32.9113.7R254 A255 K256R254-R258 WeakPolarHBondContact O-CG 3.42Å; R254-R258 PolarHBondContact O-N 2.88Å; R254-R258 VanDerWaalsContact O-N 3.09Å; R254-R258 PolarHBondContact O-NH1 2.92Å; A255-R258 PolarHBondContact O-N 3.03Å; K256-R258 VanDerWaalsContact C-N 3.28Å; K256-R258 PolarHBondContact O-N 3.2Å
259R82.7Confident76.6Confident167 Ų16785.5 Ų85.563%0.6345%0.454SS*.Hα-helixtrans-86.1-22.6178.3-66.8175.7-176.9177.80.6112.4A255 K256 I257 G261 V262A255-R259 WeakPolarHBondContact O-CG 3.26Å; A255-R259 PolarHBondContact O-N 2.84Å; K256-R259 WeakPolarHBondContact O-CB 3.33Å; K256-R259 PolarHBondContact O-N 3.23Å; I257-R259 VanDerWaalsContact C-N 3.25Å; I257-R259 PolarHBondContact O-N 3.48Å; R259-G261 PolarHBondContact O-N 3.43Å; R259-V262 PolarHBondContact O-N 3.47Å; R259-V262 VanDerWaalsContact O-N 3.09Å
260L77.1Confident76.4Confident51 Ų5188.1 Ų88.127%0.26747%0.465SS..THydrogen-bonded Turntrans-62.5110.4176.4-68.8169.3000109.9K256 I257 I277 E278 W281K256-L260 WeakPolarHBondContact O-CG 3.37Å; K256-L260 PolarHBondContact O-N 2.92Å; K256-L260 VanDerWaalsContact O-N 3.13Å; I257-L260 PolarHBondContact O-N 2.99Å; L260-I277 HydrophobicContact CD1-CG2 3.45Å; L260-I277 VanDerWaalsContact CD1-CG2 3.45Å; L260-E278 HydrophobicContact CD2-CG 3.75Å; L260-W281 HydrophobicContact CB-CZ3 4.25Å; L260-W281 HydrophobicContact CD1-CE3 3.97Å; L260-W281 HydrophobicContact CD1-CH2 3.56Å; L260-W281 HydrophobicContact CD1-CZ3 3.14Å; L260-W281 HydrophobicContact CG-CZ3 4.26Å
261G63Low76.3Confident85 Ų8586.9 Ų86.988%0.87646%0.46SS*.THydrogen-bonded Turntrans115.9-7.1-177.600000114.9R259R259-G261 PolarHBondContact O-N 3.43Å
262V68Low76.3Confident107 Ų10782 Ų8265%0.64844%0.437SS*.SBendtrans-82.9134.4161.9-175.80000107.3R259 E264R259-V262 PolarHBondContact O-N 3.47Å; R259-V262 VanDerWaalsContact O-N 3.09Å; V262-E264 PolarHBondContact O-N 3.47Å
263E55Low76.4Confident196 Ų19681.6 Ų81.692%0.91644%0.435SS*.  trans-57.5105.7173.7-77.3-174.3163.400108.9
264E59.5Low76.4Confident75 Ų7582.8 Ų82.835%0.3544%0.44SS..  trans-70.1142.6171.9-75.7-175.9163.400108.8V262 Q266 K270 Q274V262-E264 PolarHBondContact O-N 3.47Å; E264-Q266 PolarHBondContact O-N 3.47Å; E264-K270 IonicContact OE2-NZ 3.9Å; E264-Q274 PolarHBondContact OE1-NE2 2.82Å; E264-Q274 PolarHBondContact OE2-NE2 2.85Å
265P55.5Low76.3Confident96 Ų9677.4 Ų77.462%0.62342%0.421SS*.  trans-51.9129.6170.5-19.328.8000109.7G267 D268P265-G267 PolarHBondContact O-N 2.93Å; P265-D268 PolarHBondContact O-N 2.86Å
266Q44.5Very low76.4Confident210 Ų21076.6 Ų76.698%0.98142%0.415SS*.THydrogen-bonded Turntrans-57.3114.4177.2-130.9174.55.900109.2E264E264-Q266 PolarHBondContact O-N 3.47Å
267G56.2Low76.5Confident78 Ų7875.8 Ų75.880%0.80441%0.411SS*.THydrogen-bonded Turntrans109.37.9176.900000116.5P265P265-G267 PolarHBondContact O-N 2.93Å
268D68.9Low76.5Confident111 Ų11174.5 Ų74.559%0.59440%0.404SS*.PPolyproline II helixtrans-73.6138174.4-146.82.8000112.1P265P265-D268 PolarHBondContact O-N 2.86Å
269C80.3Confident76.4Confident65 Ų6567.9 Ų67.944%0.43938%0.381SS..PPolyproline II helixtrans-85.1118.8-173.2-88.50000111.4C151C151-C269 WeakPolarHBondContact CA-SG 3.5Å; C151-C269 HydrophobicContact CB-CB 3.49Å; C151-C269 VanDerWaalsContact CB-CB 3.49Å; C151-C269 WeakPolarHBondContact CB-SG 3.34Å; C151-C269 WeakPolarHBondContact SG-CA 3.36Å; C151-C269 WeakPolarHBondContact SG-CB 3.39Å; C151-C269 CovalentContact SG-SG 2.05Å; C151-C269 PolarHBondContact SG-SG 3.27Å
270K87.8Confident76.4Confident60 Ų6060 Ų6026%0.26135%0.351SS..PPolyproline II helixtrans-84.8132.3-175.5-57.2-173.8-178.9-161.60112.4Y152 E264 Q274 L275 E278Y152-K270 WeakPolarHBondContact CE1-O 3.49Å; E264-K270 IonicContact OE2-NZ 3.9Å; K270-Q274 HydrophobicContact CB-CB 4.43Å; K270-Q274 HydrophobicContact CB-CG 4.34Å; K270-Q274 HydrophobicContact CD-CG 4.25Å; K270-Q274 HydrophobicContact CG-CG 4.42Å; K270-L275 HydrophobicContact CB-CD2 3.9Å; K270-L275 HydrophobicContact CB-CG 3.91Å; K270-L275 HydrophobicContact CD-CD2 3.95Å; K270-E278 WeakPolarHBondContact CD-OE2 3.39Å; K270-E278 IonicContact NZ-OE1 3.75Å; K270-E278 PolarHBondContact NZ-OE1 3.28Å; K270-E278 IonicContact NZ-OE2 3.86Å; K270-E278 PolarHBondContact NZ-OE2 3.42Å
271D90.4Very high76.6Confident16 Ų1661.1 Ų61.19%0.08635%0.352CS..PPolyproline II helixtrans-71.6165.4169.864.485.9000112.4I192 K256 L273 Q274 L275I192-D271 WeakPolarHBondContact O-CA 3.44Å; I192-D271 WeakPolarHBondContact O-CB 3.37Å; K256-D271 VanDerWaalsContact NZ-CG 3.32Å; K256-D271 IonicContact NZ-OD1 2.78Å; K256-D271 PolarHBondContact NZ-OD1 2.87Å; K256-D271 IonicContact NZ-OD2 3.03Å; K256-D271 PolarHBondContact NZ-OD2 3.34Å; D271-L273 VanDerWaalsContact C-N 3.29Å; D271-L273 PolarHBondContact O-N 3.4Å; D271-L273 WeakPolarHBondContact OD1-CA 3.16Å; D271-L273 VanDerWaalsContact OD1-CB 3.32Å; D271-L273 WeakPolarHBondContact OD1-CB 3.44Å; D271-L273 PolarHBondContact OD1-N 3.47Å; D271-Q274 PolarHBondContact O-N 2.96Å; D271-Q274 PolarHBondContact OD1-N 3.34Å; D271-L275 WeakPolarHBondContact O-CG 3.48Å; D271-L275 PolarHBondContact O-N 3.1Å; D271-L275 VanDerWaalsContact O-N 3.07Å
272A91.4Very high77.3Confident0 Ų063.8 Ų63.80%034%0.341CS..Hα-helixtrans-59.7-38.4-176.600000112.7A143 Y152 I192 L193 L275 L276 L299A143-A272 HydrophobicContact CB-CB 3.62Å; Y152-A272 PolarHBondContact OH-N 2.97Å; I192-A272 PolarHBondContact O-N 2.99Å; L193-A272 HydrophobicContact CB-CB 4.39Å; L193-A272 HydrophobicContact CD2-CB 4.02Å; A272-L275 PolarHBondContact O-N 3.3Å; A272-L276 WeakPolarHBondContact O-CB 3.49Å; A272-L276 WeakPolarHBondContact O-CG 3.48Å; A272-L276 PolarHBondContact O-N 3.2Å; A272-L299 HydrophobicContact CB-CD1 4.25Å
273L91.5Very high77.3Confident0 Ų063.5 Ų63.50%033%0.328CS..Hα-helixtrans-68.5-40.2-179.4176.158.2000111.2L193 L194 I253 K256 D271 L276 I277 L292 S296L193-L273 VanDerWaalsContact O-CB 3.28Å; L193-L273 WeakPolarHBondContact O-CB 3.36Å; L193-L273 PolarHBondContact O-N 2.92Å; L194-L273 HydrophobicContact CD2-CD2 4.2Å; I253-L273 HydrophobicContact CG1-CD1 4.15Å; I253-L273 HydrophobicContact CG1-CD2 3.9Å; I253-L273 HydrophobicContact CG1-CG 4.46Å; K256-L273 HydrophobicContact CD-CD2 4.12Å; K256-L273 HydrophobicContact CD-CG 4.09Å; D271-L273 VanDerWaalsContact C-N 3.29Å; D271-L273 PolarHBondContact O-N 3.4Å; D271-L273 WeakPolarHBondContact OD1-CA 3.16Å; D271-L273 VanDerWaalsContact OD1-CB 3.32Å; D271-L273 WeakPolarHBondContact OD1-CB 3.44Å; D271-L273 PolarHBondContact OD1-N 3.47Å; L273-L276 WeakPolarHBondContact O-CB 3.49Å; L273-L276 PolarHBondContact O-N 3.37Å; L273-I277 HydrophobicContact CD1-CD1 4.14Å; L273-I277 HydrophobicContact CD1-CG1 4.28Å; L273-I277 HydrophobicContact CG-CD1 4.09Å; L273-I277 VanDerWaalsContact O-CG1 3.26Å; L273-I277 WeakPolarHBondContact O-CG1 3.14Å; L273-I277 PolarHBondContact O-N 3.38Å; L273-L292 HydrophobicContact CD1-CD2 4.48Å; L273-S296 WeakPolarHBondContact CD1-OG 3.48Å
274Q90.5Very high78Confident24 Ų2457.5 Ų57.511%0.11232%0.319CS..Hα-helixtrans-60.5-48.3172.9-177.6166.3-200111.5K256 E264 K270 D271 L276 I277 E278K256-Q274 HydrophobicContact CD-CB 4.43Å; E264-Q274 PolarHBondContact OE1-NE2 2.82Å; E264-Q274 PolarHBondContact OE2-NE2 2.85Å; K270-Q274 HydrophobicContact CB-CB 4.43Å; K270-Q274 HydrophobicContact CB-CG 4.34Å; K270-Q274 HydrophobicContact CD-CG 4.25Å; K270-Q274 HydrophobicContact CG-CG 4.42Å; D271-Q274 PolarHBondContact O-N 2.96Å; D271-Q274 PolarHBondContact OD1-N 3.34Å; Q274-L276 VanDerWaalsContact C-N 3.29Å; Q274-L276 PolarHBondContact O-N 3.22Å; Q274-I277 PolarHBondContact O-N 2.73Å; Q274-I277 VanDerWaalsContact O-N 3.15Å; Q274-E278 HydrophobicContact CG-CG 4.47Å; Q274-E278 WeakPolarHBondContact CG-OE1 3.05Å; Q274-E278 PolarHBondContact NE2-OE1 3Å; Q274-E278 WeakPolarHBondContact O-CG 3.43Å; Q274-E278 PolarHBondContact O-N 3.48Å
275L89.9Confident78.5Confident19 Ų1956 Ų5610%0.09931%0.312CS..Hα-helixtrans-59.9-38.9176.6-67.9172.8000112.3A143 A148 K270 D271 A272 H279A143-L275 HydrophobicContact CB-CB 4.4Å; A143-L275 HydrophobicContact CB-CD1 4.46Å; A148-L275 HydrophobicContact CB-CD1 3.69Å; K270-L275 HydrophobicContact CB-CD2 3.9Å; K270-L275 HydrophobicContact CB-CG 3.91Å; K270-L275 HydrophobicContact CD-CD2 3.95Å; D271-L275 WeakPolarHBondContact O-CG 3.48Å; D271-L275 PolarHBondContact O-N 3.1Å; D271-L275 VanDerWaalsContact O-N 3.07Å; A272-L275 PolarHBondContact O-N 3.3Å; L275-H279 WeakPolarHBondContact O-CB 3.41Å; L275-H279 PolarHBondContact O-CD2 2.9Å; L275-H279 PolarHBondContact O-N 3.29Å
276L89.3Confident79.7Confident0 Ų060 Ų600%032%0.315CS..Hα-helixtrans-62.1-44175-78.9175.6000112.5V139 I140 A272 L273 Q274 S280 L299V139-L276 HydrophobicContact CG1-CD2 3.87Å; I140-L276 HydrophobicContact CB-CD2 4.26Å; I140-L276 HydrophobicContact CG1-CD2 3.76Å; A272-L276 WeakPolarHBondContact O-CB 3.49Å; A272-L276 WeakPolarHBondContact O-CG 3.48Å; A272-L276 PolarHBondContact O-N 3.2Å; L273-L276 WeakPolarHBondContact O-CB 3.49Å; L273-L276 PolarHBondContact O-N 3.37Å; Q274-L276 VanDerWaalsContact C-N 3.29Å; Q274-L276 PolarHBondContact O-N 3.22Å; L276-S280 VanDerWaalsContact O-CB 3.25Å; L276-S280 WeakPolarHBondContact O-CB 3.43Å; L276-S280 PolarHBondContact O-N 3.45Å; L276-S280 VanDerWaalsContact O-N 3.16Å; L276-S280 PolarHBondContact O-OG 3.24Å; L276-L299 HydrophobicContact CD1-CD1 3.72Å
277I89.9Confident81.7Confident1 Ų151 Ų511%0.00527%0.273CS..Hα-helixtrans-64.3-53.6179.9-67.1163.4000109.4I253 K256 I257 L260 L273 Q274 S280 W281 L292I253-I277 HydrophobicContact CG2-CD1 4.29Å; K256-I277 HydrophobicContact CB-CD1 4.09Å; K256-I277 HydrophobicContact CD-CD1 4.27Å; I257-I277 HydrophobicContact CG1-CG2 4.41Å; L260-I277 HydrophobicContact CD1-CG2 3.45Å; L260-I277 VanDerWaalsContact CD1-CG2 3.45Å; L273-I277 HydrophobicContact CD1-CD1 4.14Å; L273-I277 HydrophobicContact CD1-CG1 4.28Å; L273-I277 HydrophobicContact CG-CD1 4.09Å; L273-I277 VanDerWaalsContact O-CG1 3.26Å; L273-I277 WeakPolarHBondContact O-CG1 3.14Å; L273-I277 PolarHBondContact O-N 3.38Å; Q274-I277 PolarHBondContact O-N 2.73Å; Q274-I277 VanDerWaalsContact O-N 3.15Å; I277-S280 PolarHBondContact O-N 3.31Å; I277-S280 PolarHBondContact O-OG 2.76Å; I277-W281 HydrophobicContact CG2-CD2 4.08Å; I277-W281 HydrophobicContact CG2-CE3 4.07Å; I277-W281 HydrophobicContact CG2-CH2 3.63Å; I277-W281 HydrophobicContact CG2-CZ2 3.57Å; I277-W281 HydrophobicContact CG2-CZ3 3.89Å; I277-W281 PolarHBondContact O-N 3.48Å; I277-L292 HydrophobicContact CG1-CD1 4.07Å; I277-L292 HydrophobicContact CG1-CD2 3.85Å
278E88.3Confident83.4Confident28 Ų2852 Ų5213%0.13126%0.26CS..Hα-helixtrans-59.1-53.5-177-69.7176.4-176.100111.9L260 K270 Q274 S280 W281 E282L260-E278 HydrophobicContact CD2-CG 3.75Å; K270-E278 WeakPolarHBondContact CD-OE2 3.39Å; K270-E278 IonicContact NZ-OE1 3.75Å; K270-E278 PolarHBondContact NZ-OE1 3.28Å; K270-E278 IonicContact NZ-OE2 3.86Å; K270-E278 PolarHBondContact NZ-OE2 3.42Å; Q274-E278 HydrophobicContact CG-CG 4.47Å; Q274-E278 WeakPolarHBondContact CG-OE1 3.05Å; Q274-E278 PolarHBondContact NE2-OE1 3Å; Q274-E278 WeakPolarHBondContact O-CG 3.43Å; Q274-E278 PolarHBondContact O-N 3.48Å; E278-S280 VanDerWaalsContact C-N 3.28Å; E278-S280 PolarHBondContact O-N 2.86Å; E278-W281 PolarHBondContact O-N 3.16Å; E278-E282 WeakPolarHBondContact O-CG 3.4Å; E278-E282 PolarHBondContact O-N 3.35Å
279H84.4Confident84.5Confident37 Ų3749.2 Ų49.217%0.17124%0.244CC..Hα-helixtrans-67.2-27.5-178.1-72-46000114Q142 L275 W281 E282 R283Q142-H279 WeakPolarHBondContact CB-CD2 3.26Å; L275-H279 WeakPolarHBondContact O-CB 3.41Å; L275-H279 PolarHBondContact O-CD2 2.9Å; L275-H279 PolarHBondContact O-N 3.29Å; H279-W281 VanDerWaalsContact C-N 3.27Å; H279-E282 IonicContact CE1-OE2 2.83Å; H279-E282 IonicContact ND1-OE2 3.06Å; H279-E282 PolarHBondContact ND1-OE2 3.33Å; H279-R283 WeakPolarHBondContact O-CG 3.38Å
280S82.7Confident85.1Confident0 Ų049.7 Ų49.70%024%0.24CC..Hα-helixtrans-65.6-35.2173.677.70000111.7L276 I277 E278 E285 R286L276-S280 VanDerWaalsContact O-CB 3.25Å; L276-S280 WeakPolarHBondContact O-CB 3.43Å; L276-S280 PolarHBondContact O-N 3.45Å; L276-S280 VanDerWaalsContact O-N 3.16Å; L276-S280 PolarHBondContact O-OG 3.24Å; I277-S280 PolarHBondContact O-N 3.31Å; I277-S280 PolarHBondContact O-OG 2.76Å; E278-S280 VanDerWaalsContact C-N 3.28Å; E278-S280 PolarHBondContact O-N 2.86Å; S280-E285 CarbonylContact O-C 3.04Å; S280-E285 WeakPolarHBondContact O-CA 3.38Å; S280-E285 PolarHBondContact O-N 3.14Å; S280-R286 PolarHBondContact O-N 3.02Å
281W80.8Confident85.3Confident76 Ų7647.2 Ų47.229%0.28823%0.231SC..Hα-helixtrans-82.2-41.4-176.6-65.4-9.1000112.6I257 L260 I277 E278 H279 R283 G284 R286I257-W281 HydrophobicContact CB-CH2 4.26Å; I257-W281 HydrophobicContact CD1-CH2 4.15Å; I257-W281 HydrophobicContact CD1-CZ2 4.01Å; I257-W281 HydrophobicContact CG1-CH2 3.69Å; I257-W281 HydrophobicContact CG1-CZ2 4.02Å; I257-W281 HydrophobicContact CG2-CH2 3.96Å; L260-W281 HydrophobicContact CB-CZ3 4.25Å; L260-W281 HydrophobicContact CD1-CE3 3.97Å; L260-W281 HydrophobicContact CD1-CH2 3.56Å; L260-W281 HydrophobicContact CD1-CZ3 3.14Å; L260-W281 HydrophobicContact CG-CZ3 4.26Å; I277-W281 HydrophobicContact CG2-CD2 4.08Å; I277-W281 HydrophobicContact CG2-CE3 4.07Å; I277-W281 HydrophobicContact CG2-CH2 3.63Å; I277-W281 HydrophobicContact CG2-CZ2 3.57Å; I277-W281 HydrophobicContact CG2-CZ3 3.89Å; I277-W281 PolarHBondContact O-N 3.48Å; E278-W281 PolarHBondContact O-N 3.16Å; H279-W281 VanDerWaalsContact C-N 3.27Å; W281-R283 PolarHBondContact O-N 2.86Å; W281-G284 PolarHBondContact O-N 3.21Å; W281-G284 VanDerWaalsContact O-N 3.15Å; W281-R286 VanDerWaalsContact CD1-CG 3.49Å
282E77.9Confident85.4Confident140 Ų14046.6 Ų46.665%0.65423%0.228SC*.Hα-helixtrans-56.6-34.2176.9-71.2174162.500112.8E278 H279E278-E282 WeakPolarHBondContact O-CG 3.4Å; E278-E282 PolarHBondContact O-N 3.35Å; H279-E282 IonicContact CE1-OE2 2.83Å; H279-E282 IonicContact ND1-OE2 3.06Å; H279-E282 PolarHBondContact ND1-OE2 3.33Å
283R69.5Low85.5Confident101 Ų10147.8 Ų47.838%0.38123%0.233SC..THydrogen-bonded Turntrans-92.74-174.6-60.1-175.169.7-118.4-19.6113.4H279 W281 E285H279-R283 WeakPolarHBondContact O-CG 3.38Å; W281-R283 PolarHBondContact O-N 2.86Å; R283-E285 HydrophobicContact CB-CG 4.19Å; R283-E285 IonicContact CZ-OE2 3.8Å; R283-E285 IonicContact NH1-OE1 3.11Å; R283-E285 IonicContact NH1-OE2 3.55Å; R283-E285 PolarHBondContact NH1-OE2 3.34Å; R283-E285 IonicContact NH2-OE1 2.81Å; R283-E285 IonicContact NH2-OE2 3.53Å; R283-E285 PolarHBondContact O-N 3.26Å
284G67.8Low85.5Confident70 Ų7048.7 Ų48.772%0.72224%0.237SC*.THydrogen-bonded Turntrans66.811.1-17300000113.7W281 R286W281-G284 PolarHBondContact O-N 3.21Å; W281-G284 VanDerWaalsContact O-N 3.15Å; G284-R286 VanDerWaalsContact C-N 3.32Å; G284-R286 PolarHBondContact O-N 2.82Å
285E70.6Confident85.6Confident43 Ų4347.5 Ų47.520%0.20123%0.231CC..  trans-98.844.9-179-59-177.215200110.2Q135 S280 R283 L287Q135-E285 WeakPolarHBondContact CG-OE1 3.43Å; Q135-E285 VanDerWaalsContact NE2-CG 3.32Å; Q135-E285 PolarHBondContact NE2-OE1 2.92Å; S280-E285 CarbonylContact O-C 3.04Å; S280-E285 WeakPolarHBondContact O-CA 3.38Å; S280-E285 PolarHBondContact O-N 3.14Å; R283-E285 HydrophobicContact CB-CG 4.19Å; R283-E285 IonicContact CZ-OE2 3.8Å; R283-E285 IonicContact NH1-OE1 3.11Å; R283-E285 IonicContact NH1-OE2 3.55Å; R283-E285 PolarHBondContact NH1-OE2 3.34Å; R283-E285 IonicContact NH2-OE1 2.81Å; R283-E285 IonicContact NH2-OE2 3.53Å; R283-E285 PolarHBondContact O-N 3.26Å; E285-L287 PolarHBondContact O-N 3.38Å
286R80.9Confident85.7Confident182 Ų18246.7 Ų46.769%0.68723%0.227SC*.  trans-55.4110-169.5174.8158.5-168.4-169.36.8111S280 W281 G284 D288S280-R286 PolarHBondContact O-N 3.02Å; W281-R286 VanDerWaalsContact CD1-CG 3.49Å; G284-R286 VanDerWaalsContact C-N 3.32Å; G284-R286 PolarHBondContact O-N 2.82Å; R286-D288 PolarHBondContact O-N 3.17Å
287L86.7Confident85.8Confident20 Ų2046.7 Ų46.711%0.10523%0.227CC..  trans-69.7128.5173.5-63.3-176.3000108.6V139 E285 A291 L292V139-L287 HydrophobicContact CG1-CD1 4.46Å; E285-L287 PolarHBondContact O-N 3.38Å; L287-A291 HydrophobicContact CB-CB 4.16Å; L287-A291 HydrophobicContact CD2-CB 4.32Å; L287-L292 HydrophobicContact CB-CD2 3.91Å; L287-L292 HydrophobicContact CB-CG 3.89Å; L287-L292 HydrophobicContact CD1-CD2 3.98Å
288D90.9Very high85.8Confident100 Ų10047.8 Ų47.854%0.53523%0.232SC..  trans-71.6171.5171.468.640.4000111.4R286 Q290 A291 L292R286-D288 PolarHBondContact O-N 3.17Å; D288-Q290 VanDerWaalsContact C-N 3.27Å; D288-Q290 PolarHBondContact O-N 3.36Å; D288-Q290 WeakPolarHBondContact OD1-CA 3.23Å; D288-Q290 WeakPolarHBondContact OD1-CB 3.1Å; D288-Q290 PolarHBondContact OD1-N 2.95Å; D288-A291 WeakPolarHBondContact O-CB 3.34Å; D288-A291 PolarHBondContact O-N 2.72Å; D288-A291 VanDerWaalsContact OD1-CB 3.27Å; D288-A291 WeakPolarHBondContact OD1-CB 3.22Å; D288-A291 PolarHBondContact OD1-N 2.96Å; D288-L292 WeakPolarHBondContact O-CG 3.24Å; D288-L292 PolarHBondContact O-N 3.49Å
289M92.3Very high85.9Confident51 Ų5147.1 Ų47.125%0.25123%0.229SC..Hα-helixtrans-57.8-39.9-178.6-177.858.275.400112.4E250 I253 R254 L292 K293E250-M289 HydrophobicContact CB-SD 4.42Å; E250-M289 HydrophobicContact CG-CE 4.08Å; E250-M289 HydrophobicContact CG-CG 4.14Å; E250-M289 HydrophobicContact CG-SD 3.77Å; I253-M289 HydrophobicContact CB-CE 4.23Å; I253-M289 HydrophobicContact CB-SD 4Å; I253-M289 HydrophobicContact CD1-SD 3.74Å; I253-M289 HydrophobicContact CG1-SD 4.49Å; I253-M289 HydrophobicContact CG2-CE 3.68Å; I253-M289 HydrophobicContact CG2-SD 3.74Å; R254-M289 HydrophobicContact CG-CE 3.84Å; M289-L292 PolarHBondContact O-N 3.44Å; M289-K293 HydrophobicContact CG-CD 4.35Å; M289-K293 VanDerWaalsContact O-CG 3.32Å; M289-K293 WeakPolarHBondContact O-CG 3.39Å; M289-K293 PolarHBondContact O-N 3.06Å; M289-K293 HydrophobicContact SD-CG 4.41Å
290Q93.1Very high86.2Confident76 Ų7645.5 Ų45.536%0.35522%0.222SC..Hα-helixtrans-69.6-44.2-178.1-176.360.421.700110.9D288 L292 K293 E294D288-Q290 VanDerWaalsContact C-N 3.27Å; D288-Q290 PolarHBondContact O-N 3.36Å; D288-Q290 WeakPolarHBondContact OD1-CA 3.23Å; D288-Q290 WeakPolarHBondContact OD1-CB 3.1Å; D288-Q290 PolarHBondContact OD1-N 2.95Å; Q290-L292 VanDerWaalsContact C-N 3.29Å; Q290-L292 PolarHBondContact O-N 3.24Å; Q290-K293 PolarHBondContact O-N 3.27Å; Q290-E294 PolarHBondContact NE2-OE1 2.83Å; Q290-E294 WeakPolarHBondContact O-CB 3.5Å; Q290-E294 WeakPolarHBondContact O-CG 3.28Å; Q290-E294 PolarHBondContact O-N 3.3Å
291A91.6Very high86.5Confident8 Ų847.5 Ų47.57%0.06623%0.231CC..Hα-helixtrans-58.4-38.7174.300000112.6R136 L287 D288 S295R136-A291 PolarHBondContact NH1-O 3.45Å; R136-A291 VanDerWaalsContact NH2-CB 3.31Å; L287-A291 HydrophobicContact CB-CB 4.16Å; L287-A291 HydrophobicContact CD2-CB 4.32Å; D288-A291 WeakPolarHBondContact O-CB 3.34Å; D288-A291 PolarHBondContact O-N 2.72Å; D288-A291 VanDerWaalsContact OD1-CB 3.27Å; D288-A291 WeakPolarHBondContact OD1-CB 3.22Å; D288-A291 PolarHBondContact OD1-N 2.96Å; A291-S295 WeakPolarHBondContact O-CB 3.45Å; A291-S295 PolarHBondContact O-N 2.93Å; A291-S295 VanDerWaalsContact O-N 3.07Å; A291-S295 PolarHBondContact O-OG 3.3Å
292L92.5Very high86.9Confident3 Ų345.5 Ų45.52%0.01623%0.234CC..Hα-helixtrans-68.1-49.2174.4-71.7168.9000111I253 L273 I277 L287 D288 M289 Q290 E294 S295 S296I253-L292 HydrophobicContact CD1-CB 3.58Å; I253-L292 HydrophobicContact CG1-CB 4.43Å; I253-L292 HydrophobicContact CG2-CD1 3.86Å; L273-L292 HydrophobicContact CD1-CD2 4.48Å; I277-L292 HydrophobicContact CG1-CD1 4.07Å; I277-L292 HydrophobicContact CG1-CD2 3.85Å; L287-L292 HydrophobicContact CB-CD2 3.91Å; L287-L292 HydrophobicContact CB-CG 3.89Å; L287-L292 HydrophobicContact CD1-CD2 3.98Å; D288-L292 WeakPolarHBondContact O-CG 3.24Å; D288-L292 PolarHBondContact O-N 3.49Å; M289-L292 PolarHBondContact O-N 3.44Å; Q290-L292 VanDerWaalsContact C-N 3.29Å; Q290-L292 PolarHBondContact O-N 3.24Å; L292-E294 VanDerWaalsContact C-N 3.31Å; L292-E294 PolarHBondContact O-N 3.37Å; L292-S295 PolarHBondContact O-N 3.15Å; L292-S295 VanDerWaalsContact O-N 3.15Å; L292-S296 WeakPolarHBondContact O-CB 3.3Å; L292-S296 PolarHBondContact O-N 2.78Å; L292-S296 PolarHBondContact O-OG 2.83Å
293K93.6Very high87.4Confident24 Ų2439.4 Ų39.410%0.10421%0.209CC..Hα-helixtrans-56.5-43.6177.3-70.9-177.3-53.6-172.60112.9H246 I249 E250 I253 M289 Q290 S296 T297H246-K293 HydrophobicContact CB-CD 4.08Å; H246-K293 WeakPolarHBondContact O-CD 3.34Å; I249-K293 HydrophobicContact CG2-CB 4.47Å; I249-K293 HydrophobicContact CG2-CG 4.06Å; E250-K293 HydrophobicContact CB-CD 3.92Å; E250-K293 HydrophobicContact CG-CD 4.47Å; E250-K293 IonicContact OE2-NZ 2.85Å; E250-K293 PolarHBondContact OE2-NZ 3.44Å; I253-K293 HydrophobicContact CD1-CG 3.9Å; M289-K293 HydrophobicContact CG-CD 4.35Å; M289-K293 VanDerWaalsContact O-CG 3.32Å; M289-K293 WeakPolarHBondContact O-CG 3.39Å; M289-K293 PolarHBondContact O-N 3.06Å; M289-K293 HydrophobicContact SD-CG 4.41Å; Q290-K293 PolarHBondContact O-N 3.27Å; K293-S296 PolarHBondContact O-N 2.84Å; K293-T297 WeakPolarHBondContact O-CB 3.47Å; K293-T297 PolarHBondContact O-N 3.15Å; K293-T297 PolarHBondContact O-OG1 3.09Å
294E93Very high88.5Confident19 Ų1934.8 Ų34.89%0.08919%0.192CC..Hα-helixtrans-68.3-38.2178.1-73.4179.5176.400112.3G123 C124 Q290 L292 E298G123-E294 VanDerWaalsContact C-OE2 3.28Å; G123-E294 WeakPolarHBondContact CA-OE2 3.49Å; G123-E294 PolarHBondContact N-OE2 3.44Å; C124-E294 PolarHBondContact SG-O 3.48Å; Q290-E294 PolarHBondContact NE2-OE1 2.83Å; Q290-E294 WeakPolarHBondContact O-CB 3.5Å; Q290-E294 WeakPolarHBondContact O-CG 3.28Å; Q290-E294 PolarHBondContact O-N 3.3Å; L292-E294 VanDerWaalsContact C-N 3.31Å; L292-E294 PolarHBondContact O-N 3.37Å; E294-E298 VanDerWaalsContact O-CB 3.31Å; E294-E298 WeakPolarHBondContact O-CB 3.32Å; E294-E298 PolarHBondContact O-N 3.44Å
295S92.3Very high89.5Confident0 Ų032.1 Ų32.10%016%0.16CC..Hα-helixtrans-67-44175.1-56.40000111.2R136 A291 L292 E298 L299R136-S295 PolarHBondContact NH1-OG 3Å; A291-S295 WeakPolarHBondContact O-CB 3.45Å; A291-S295 PolarHBondContact O-N 2.93Å; A291-S295 VanDerWaalsContact O-N 3.07Å; A291-S295 PolarHBondContact O-OG 3.3Å; L292-S295 PolarHBondContact O-N 3.15Å; L292-S295 VanDerWaalsContact O-N 3.15Å; S295-E298 PolarHBondContact O-N 3.42Å; S295-L299 WeakPolarHBondContact O-CB 3.48Å; S295-L299 WeakPolarHBondContact O-CG 3.25Å; S295-L299 PolarHBondContact O-N 3.32Å
296S91.9Very high90.7Very high1 Ų132.2 Ų32.21%0.00716%0.164CC..Hα-helixtrans-59.9-47.7176.3-65.30000112.2L273 L292 K293 E298 L299 L300L273-S296 WeakPolarHBondContact CD1-OG 3.48Å; L292-S296 WeakPolarHBondContact O-CB 3.3Å; L292-S296 PolarHBondContact O-N 2.78Å; L292-S296 PolarHBondContact O-OG 2.83Å; K293-S296 PolarHBondContact O-N 2.84Å; S296-E298 VanDerWaalsContact C-N 3.31Å; S296-E298 PolarHBondContact O-N 2.78Å; S296-L299 PolarHBondContact O-N 3.05Å; S296-L300 PolarHBondContact O-N 3.19Å
297T91.4Very high91.5Very high0 Ų023.7 Ų23.70%013%0.132CC..Hα-helixtrans-62.8-39.4178.3-58.80000111.5M219 H246 I249 K293 F301M219-T297 HydrophobicContact CE-CG2 3.87Å; M219-T297 HydrophobicContact SD-CG2 3.86Å; H246-T297 PolarHBondContact CD2-OG1 3.28Å; H246-T297 VanDerWaalsContact CD2-OG1 3.28Å; H246-T297 PolarHBondContact NE2-OG1 2.96Å; I249-T297 WeakPolarHBondContact CD1-OG1 3.21Å; K293-T297 WeakPolarHBondContact O-CB 3.47Å; K293-T297 PolarHBondContact O-N 3.15Å; K293-T297 PolarHBondContact O-OG1 3.09Å; T297-F301 WeakPolarHBondContact O-CB 3.46Å; T297-F301 PolarHBondContact O-N 3.16Å
298E89.8Confident92Very high24 Ų2422.8 Ų22.811%0.11213%0.127CC..Hα-helixtrans-67.9-39.7175.7178.2171.7-133.500113.1C124 L125 S126 E294 S295 S296 F301 G302C124-E298 HydrophobicContact CB-CB 4.37Å; L125-E298 WeakPolarHBondContact CA-OE2 3.42Å; L125-E298 WeakPolarHBondContact CB-OE2 3.27Å; L125-E298 PolarHBondContact N-OE1 3.36Å; L125-E298 PolarHBondContact N-OE2 3.42Å; S126-E298 WeakPolarHBondContact CA-OE1 3.38Å; S126-E298 WeakPolarHBondContact CB-OE1 3.28Å; S126-E298 PolarHBondContact N-OE1 3.19Å; S126-E298 PolarHBondContact OG-OE1 3.49Å; E294-E298 VanDerWaalsContact O-CB 3.31Å; E294-E298 WeakPolarHBondContact O-CB 3.32Å; E294-E298 PolarHBondContact O-N 3.44Å; S295-E298 PolarHBondContact O-N 3.42Å; S296-E298 VanDerWaalsContact C-N 3.31Å; S296-E298 PolarHBondContact O-N 2.78Å; E298-F301 PolarHBondContact O-N 3.17Å; E298-G302 PolarHBondContact O-N 3.31Å
299L91Very high92.3Very high14 Ų1418 Ų187%0.07310%0.102CC..Hα-helixtrans-62.2-46.4175-76.1-173.3000111.1I140 F144 L193 A272 L276 S295 S296 F301 G302 G303I140-L299 HydrophobicContact CG2-CD2 3.89Å; F144-L299 HydrophobicContact CE2-CD2 3.79Å; F144-L299 HydrophobicContact CZ-CD2 3.75Å; L193-L299 HydrophobicContact CB-CB 4.42Å; L193-L299 HydrophobicContact CD1-CB 4.06Å; L193-L299 VanDerWaalsContact CD1-O 3.31Å; L193-L299 WeakPolarHBondContact CD1-O 3.31Å; A272-L299 HydrophobicContact CB-CD1 4.25Å; L276-L299 HydrophobicContact CD1-CD1 3.72Å; S295-L299 WeakPolarHBondContact O-CB 3.48Å; S295-L299 WeakPolarHBondContact O-CG 3.25Å; S295-L299 PolarHBondContact O-N 3.32Å; S296-L299 PolarHBondContact O-N 3.05Å; L299-F301 PolarHBondContact O-N 2.87Å; L299-G302 PolarHBondContact O-N 3.29Å; L299-G303 PolarHBondContact O-N 2.84Å
300L89.9Confident92.6Very high3 Ų315.7 Ų15.72%0.0169%0.091CC..Hα-helixtrans-57.1-49172.4-75.5-178.6000111.5A189 M190 L194 F216 I249 S296 G302 G303 H304A189-L300 HydrophobicContact CB-CD2 3.78Å; M190-L300 HydrophobicContact SD-CD1 4.21Å; M190-L300 HydrophobicContact SD-CD2 4.03Å; L194-L300 HydrophobicContact CD1-CD1 3.65Å; L194-L300 HydrophobicContact CD1-CD2 4.07Å; L194-L300 HydrophobicContact CD1-CG 4.01Å; L194-L300 HydrophobicContact CG-CD1 4.46Å; L194-L300 HydrophobicContact CG-CD2 4.17Å; L194-L300 HydrophobicContact CG-CG 4.29Å; F216-L300 HydrophobicContact CE2-CB 3.73Å; F216-L300 HydrophobicContact CZ-CB 4.22Å; I249-L300 HydrophobicContact CD1-CD1 4.46Å; S296-L300 PolarHBondContact O-N 3.19Å; L300-G302 PolarHBondContact O-N 2.97Å; L300-G303 PolarHBondContact O-N 2.87Å; L300-H304 VanDerWaalsContact O-CB 3.29Å; L300-H304 WeakPolarHBondContact O-CB 3.24Å; L300-H304 PolarHBondContact O-N 3.38Å; L300-H304 VanDerWaalsContact O-N 3.09Å
301F88.8Confident92.9Very high42 Ų4212.1 Ų12.118%0.1847%0.074CC..Hα-helixtrans-57.3-49.2178176.2-113.7000112.7L120 T220 L223 T297 E298 L299L120-F301 HydrophobicContact CD1-CD1 4.19Å; L120-F301 HydrophobicContact CD1-CE1 4.33Å; L120-F301 HydrophobicContact CD2-CB 4.38Å; L120-F301 HydrophobicContact CD2-CD1 4.38Å; L120-F301 HydrophobicContact CD2-CG 4.26Å; T220-F301 HydrophobicContact CG2-CD2 3.89Å; T220-F301 HydrophobicContact CG2-CE2 4.19Å; L223-F301 HydrophobicContact CD1-CD2 3.85Å; L223-F301 HydrophobicContact CD1-CE1 4.43Å; L223-F301 HydrophobicContact CD1-CE2 3.23Å; L223-F301 HydrophobicContact CD1-CZ 3.57Å; T297-F301 WeakPolarHBondContact O-CB 3.46Å; T297-F301 PolarHBondContact O-N 3.16Å; E298-F301 PolarHBondContact O-N 3.17Å; L299-F301 PolarHBondContact O-N 2.87Å
302G89.4Confident93.2Very high35 Ų3511.8 Ų11.836%0.3617%0.071SC..Hα-helixtrans-66.6-39.5179.600000113E298 L299 L300 T306E298-G302 PolarHBondContact O-N 3.31Å; L299-G302 PolarHBondContact O-N 3.29Å; L300-G302 PolarHBondContact O-N 2.97Å; G302-T306 PolarHBondContact O-OG1 3.43Å
303G89.4Confident93.5Very high12 Ų1211.6 Ų11.612%0.1247%0.07CC..Hα-helixtrans-81.1-12.1-174.500000115.8L299 L300 T307L299-G303 PolarHBondContact O-N 2.84Å; L300-G303 PolarHBondContact O-N 2.87Å; G303-T307 WeakPolarHBondContact O-CG2 3.47Å; G303-T307 PolarHBondContact O-OG1 3.46Å
304H91.3Very high93.7Very high4 Ų410.5 Ų10.52%0.0197%0.066CC..Hα-helixtrans-99-68.2-177.2172.8-105.9000113.7K182 F186 F216 L300 T306 T307 A308K182-H304 WeakPolarHBondContact CE-CE1 3.42Å; K182-H304 PolarHBondContact O-CD2 3.25Å; K182-H304 VanDerWaalsContact O-CD2 3.25Å; K182-H304 PolarHBondContact O-NE2 2.87Å; F186-H304 PolarHBondContact N-CD2 3.43Å; F216-H304 HydrophobicContact CE1-CB 3.92Å; F216-H304 AromaticContact CE1-CE1 3.95Å; F216-H304 AromaticContact CE1-CG 3.71Å; F216-H304 AromaticContact CE1-ND1 3.39Å; F216-H304 WeakPolarHBondContact CE1-ND1 3.34Å; F216-H304 HydrophobicContact CZ-CB 4.09Å; L300-H304 VanDerWaalsContact O-CB 3.29Å; L300-H304 WeakPolarHBondContact O-CB 3.24Å; L300-H304 PolarHBondContact O-N 3.38Å; L300-H304 VanDerWaalsContact O-N 3.09Å; H304-T306 VanDerWaalsContact C-N 3.33Å; H304-T306 PolarHBondContact O-N 3.31Å; H304-T307 PolarHBondContact O-OG1 3.27Å; H304-A308 VanDerWaalsContact O-CB 3.23Å; H304-A308 WeakPolarHBondContact O-CB 3.25Å; H304-A308 PolarHBondContact O-N 3.07Å
305E89.8Confident94Very high14 Ų149.6 Ų9.67%0.0656%0.061CC..Hα-helixtrans-67.3-34.7-168.6-77.4-67.5159.500112.3K182 S309 T481K182-E305 WeakPolarHBondContact CE-OE1 3.49Å; K182-E305 IonicContact NZ-OE1 3.33Å; K182-E305 PolarHBondContact NZ-OE1 2.84Å; K182-E305 VanDerWaalsContact NZ-OE1 3.11Å; E305-S309 VanDerWaalsContact O-CB 3.27Å; E305-S309 WeakPolarHBondContact O-CB 3.48Å; E305-S309 PolarHBondContact O-N 2.83Å; E305-S309 VanDerWaalsContact O-N 3.16Å; E305-T481 HydrophobicContact CB-CG2 4.04Å
306T95.6Very high94.3Very high45 Ų459.8 Ų9.828%0.2766%0.063SC..Hα-helixtrans-78.5-40.2-175.768.50000112.8G302 H304 A310 P371 V372 T481G302-T306 PolarHBondContact O-OG1 3.43Å; H304-T306 VanDerWaalsContact C-N 3.33Å; H304-T306 PolarHBondContact O-N 3.31Å; T306-A310 PolarHBondContact O-N 3.23Å; T306-A310 VanDerWaalsContact O-N 3.1Å; T306-P371 HydrophobicContact CG2-CB 4.45Å; T306-P371 WeakPolarHBondContact O-CB 3.5Å; T306-P371 VanDerWaalsContact O-CG 3.24Å; T306-P371 WeakPolarHBondContact O-CG 3.27Å; T306-V372 HydrophobicContact CG2-CG2 3.9Å; T306-T481 HydrophobicContact CG2-CG2 4.22Å
307T96.9Very high94.6Very high3 Ų311.5 Ų11.52%0.0187%0.069CC..Hα-helixtrans-70.4-38.617653.50000110.5M185 G303 H304 A310 A311 A450 L453M185-T307 WeakPolarHBondContact CG-OG1 3.47Å; G303-T307 WeakPolarHBondContact O-CG2 3.47Å; G303-T307 PolarHBondContact O-OG1 3.46Å; H304-T307 PolarHBondContact O-OG1 3.27Å; T307-A310 PolarHBondContact O-N 3.22Å; T307-A311 VanDerWaalsContact O-CB 3.25Å; T307-A311 WeakPolarHBondContact O-CB 3.45Å; T307-A311 PolarHBondContact O-N 3.28Å; T307-A450 HydrophobicContact CG2-CB 4.43Å; T307-L453 HydrophobicContact CG2-CD1 4.49Å
308A97Very high94.9Very high0 Ų011.5 Ų11.50%07%0.07CC..Hα-helixtrans-62-47.1175.900000111.3V181 K182 M185 H304 A310 A311 T312V181-A308 HydrophobicContact CG1-CB 3.95Å; K182-A308 HydrophobicContact CG-CB 3.92Å; M185-A308 HydrophobicContact CB-CB 4.29Å; M185-A308 HydrophobicContact CG-CB 3.84Å; H304-A308 VanDerWaalsContact O-CB 3.23Å; H304-A308 WeakPolarHBondContact O-CB 3.25Å; H304-A308 PolarHBondContact O-N 3.07Å; A308-A310 VanDerWaalsContact C-N 3.34Å; A308-A310 PolarHBondContact O-N 2.9Å; A308-A311 PolarHBondContact O-N 3.4Å; A308-T312 WeakPolarHBondContact O-CB 3.48Å; A308-T312 PolarHBondContact O-N 2.87Å; A308-T312 PolarHBondContact O-OG1 2.91Å
309S97.8Very high95.3Very high1 Ų111.4 Ų11.41%0.0078%0.075CC..Hα-helixtrans-55.1-45.7173.6174.90000113E305 S313 V482E305-S309 VanDerWaalsContact O-CB 3.27Å; E305-S309 WeakPolarHBondContact O-CB 3.48Å; E305-S309 PolarHBondContact O-N 2.83Å; E305-S309 VanDerWaalsContact O-N 3.16Å; S309-S313 WeakPolarHBondContact O-CB 3.47Å; S309-S313 PolarHBondContact O-N 3.31Å; S309-S313 PolarHBondContact O-OG 2.79Å; S309-V482 WeakPolarHBondContact CB-O 3.47Å; S309-V482 PolarHBondContact OG-N 2.9Å; S309-V482 PolarHBondContact OG-O 3.07Å
310A98.4Very high95.6Very high2 Ų213.6 Ų13.62%0.0179%0.087CC..Hα-helixtrans-68.2-45.2178.700000112.4T306 T307 A308 S313 L314 L366 P371 L454T306-A310 PolarHBondContact O-N 3.23Å; T306-A310 VanDerWaalsContact O-N 3.1Å; T307-A310 PolarHBondContact O-N 3.22Å; A308-A310 VanDerWaalsContact C-N 3.34Å; A308-A310 PolarHBondContact O-N 2.9Å; A310-S313 WeakPolarHBondContact O-CB 3.47Å; A310-S313 PolarHBondContact O-N 2.88Å; A310-L314 WeakPolarHBondContact O-CG 3.41Å; A310-L314 PolarHBondContact O-N 3.27Å; A310-L366 HydrophobicContact CB-CD2 3.93Å; A310-P371 HydrophobicContact CB-CG 3.87Å; A310-L454 HydrophobicContact CB-CD1 3.83Å; A310-L454 HydrophobicContact CB-CD2 3.81Å; A310-L454 HydrophobicContact CB-CG 4.49Å
311A98.7Very high95.9Very high0 Ų015.5 Ų15.50%010%0.095CC..Hα-helixtrans-63.9-43.7179.300000112.2V181 M185 T307 A308 S313 L314 I315 L454 F457V181-A311 HydrophobicContact CG1-CB 3.74Å; M185-A311 HydrophobicContact CE-CB 3.77Å; T307-A311 VanDerWaalsContact O-CB 3.25Å; T307-A311 WeakPolarHBondContact O-CB 3.45Å; T307-A311 PolarHBondContact O-N 3.28Å; A308-A311 PolarHBondContact O-N 3.4Å; A311-S313 VanDerWaalsContact C-N 3.33Å; A311-S313 PolarHBondContact O-N 3.47Å; A311-L314 WeakPolarHBondContact O-CB 3.49Å; A311-L314 PolarHBondContact O-N 2.9Å; A311-I315 PolarHBondContact O-N 3.03Å; A311-L454 HydrophobicContact CB-CD2 4.09Å; A311-F457 HydrophobicContact CB-CD1 3.89Å; A311-F457 HydrophobicContact CB-CE1 3.56Å; A311-F457 HydrophobicContact CB-CZ 3.96Å
312T98.6Very high96.3Very high1 Ų117.8 Ų17.81%0.00611%0.114CC..Hα-helixtrans-64.4-38.7173.7-59.50000111.8V177 Y178 A308 L314 I315 A316 P484 L488V177-T312 HydrophobicContact CG1-CG2 4.37Å; Y178-T312 HydrophobicContact CD2-CG2 4.1Å; Y178-T312 WeakPolarHBondContact CD2-OG1 3.24Å; Y178-T312 HydrophobicContact CG-CG2 4.49Å; A308-T312 WeakPolarHBondContact O-CB 3.48Å; A308-T312 PolarHBondContact O-N 2.87Å; A308-T312 PolarHBondContact O-OG1 2.91Å; T312-L314 VanDerWaalsContact C-N 3.33Å; T312-L314 PolarHBondContact O-N 3.43Å; T312-I315 PolarHBondContact O-N 3.5Å; T312-A316 PolarHBondContact O-N 2.87Å; T312-P484 HydrophobicContact CG2-CG 3.75Å; T312-L488 HydrophobicContact CG2-CB 4.37Å; T312-L488 HydrophobicContact CG2-CD2 3.74Å
313S98.5Very high96.6Very high0 Ų021.4 Ų21.40%012%0.122CC..Hα-helixtrans-64.3-37.7174-62.10000111.9S309 A310 A311 A316 Y317 N369S309-S313 WeakPolarHBondContact O-CB 3.47Å; S309-S313 PolarHBondContact O-N 3.31Å; S309-S313 PolarHBondContact O-OG 2.79Å; A310-S313 WeakPolarHBondContact O-CB 3.47Å; A310-S313 PolarHBondContact O-N 2.88Å; A311-S313 VanDerWaalsContact C-N 3.33Å; A311-S313 PolarHBondContact O-N 3.47Å; S313-A316 PolarHBondContact O-N 3.42Å; S313-Y317 WeakPolarHBondContact O-CD2 3.32Å; S313-Y317 PolarHBondContact O-N 2.89Å; S313-N369 PolarHBondContact OG-ND2 3.47Å
314L98.5Very high97.1Very high1 Ų120.9 Ų20.91%0.00512%0.116CC..Hα-helixtrans-60.5-49173.9-80.6164.6000111.4A310 A311 T312 A316 Y317 L318 V361 I362 T365 L454A310-L314 WeakPolarHBondContact O-CG 3.41Å; A310-L314 PolarHBondContact O-N 3.27Å; A311-L314 WeakPolarHBondContact O-CB 3.49Å; A311-L314 PolarHBondContact O-N 2.9Å; T312-L314 VanDerWaalsContact C-N 3.33Å; T312-L314 PolarHBondContact O-N 3.43Å; L314-A316 VanDerWaalsContact C-N 3.3Å; L314-A316 PolarHBondContact O-N 3.33Å; L314-Y317 PolarHBondContact O-N 3.25Å; L314-L318 VanDerWaalsContact O-CB 3.32Å; L314-L318 WeakPolarHBondContact O-CB 3.38Å; L314-L318 WeakPolarHBondContact O-CG 3.04Å; L314-L318 PolarHBondContact O-N 3.42Å; L314-V361 HydrophobicContact CD2-CG1 3.95Å; L314-I362 HydrophobicContact CD1-CG1 4.23Å; L314-I362 HydrophobicContact CD2-CG1 4.1Å; L314-T365 HydrophobicContact CD2-CG2 4.21Å; L314-T365 VanDerWaalsContact CD2-OG1 3.29Å; L314-T365 WeakPolarHBondContact CD2-OG1 3.47Å; L314-T365 HydrophobicContact CG-CG2 3.99Å; L314-L454 HydrophobicContact CD1-CB 4.13Å; L314-L454 HydrophobicContact CD1-CD2 3.78Å; L314-L454 HydrophobicContact CD1-CG 4.42Å
315I98.6Very high97.3Very high0 Ų021.3 Ų21.30%012%0.118CC..Hα-helixtrans-57-45.4176.6-70172000110.7W167 V177 V181 A311 T312 G319 F457 L461 W467 L488 F492W167-I315 HydrophobicContact CH2-CD1 4.05Å; W167-I315 HydrophobicContact CZ3-CD1 3.85Å; V177-I315 HydrophobicContact CG1-CB 4.45Å; V177-I315 HydrophobicContact CG1-CD1 3.47Å; V177-I315 VanDerWaalsContact CG1-CD1 3.47Å; V177-I315 HydrophobicContact CG1-CG2 4.22Å; V181-I315 HydrophobicContact CG2-CD1 4.04Å; A311-I315 PolarHBondContact O-N 3.03Å; T312-I315 PolarHBondContact O-N 3.5Å; I315-G319 PolarHBondContact O-N 3.36Å; I315-F457 HydrophobicContact CD1-CE1 4.03Å; I315-F457 HydrophobicContact CD1-CZ 3.68Å; I315-F457 HydrophobicContact CG1-CE1 4.03Å; I315-F457 HydrophobicContact CG1-CZ 4.18Å; I315-L461 HydrophobicContact CD1-CD1 4.21Å; I315-L461 HydrophobicContact CG1-CD1 3.65Å; I315-W467 PolarHBondContact O-NE1 3.05Å; I315-L488 HydrophobicContact CB-CD2 4.37Å; I315-L488 HydrophobicContact CG2-CD2 4.03Å; I315-F492 HydrophobicContact CD1-CZ 4.45Å; I315-F492 HydrophobicContact CG2-CZ 4.3Å
316A98.4Very high97.7Very high4 Ų424.5 Ų24.53%0.03313%0.133CC..Hα-helixtrans-62-51.2179.100000111.7T312 S313 L314 G319 L320 P474 L488T312-A316 PolarHBondContact O-N 2.87Å; S313-A316 PolarHBondContact O-N 3.42Å; L314-A316 VanDerWaalsContact C-N 3.3Å; L314-A316 PolarHBondContact O-N 3.33Å; A316-G319 PolarHBondContact O-N 3.07Å; A316-L320 WeakPolarHBondContact O-CB 3.33Å; A316-L320 WeakPolarHBondContact O-CG 3.48Å; A316-L320 PolarHBondContact O-N 3.06Å; A316-P474 HydrophobicContact CB-CG 4.03Å; A316-L488 HydrophobicContact CB-CD1 4.06Å; A316-L488 HydrophobicContact CB-CD2 3.98Å
317Y98.4Very high97.7Very high36 Ų3626.2 Ų26.214%0.14114%0.137CC..Hα-helixtrans-66.6-44.6-177.9-75.7-58.3000112.6S313 L314 G319 L320 H321 T365 L368 N369 F416S313-Y317 WeakPolarHBondContact O-CD2 3.32Å; S313-Y317 PolarHBondContact O-N 2.89Å; L314-Y317 PolarHBondContact O-N 3.25Å; Y317-G319 PolarHBondContact O-N 2.87Å; Y317-L320 PolarHBondContact O-N 2.9Å; Y317-H321 WeakPolarHBondContact O-CB 3.31Å; Y317-H321 PolarHBondContact O-N 2.97Å; Y317-H321 PolarHBondContact O-ND1 3.15Å; Y317-T365 HydrophobicContact CD2-CG2 3.94Å; Y317-T365 HydrophobicContact CE2-CG2 4.25Å; Y317-L368 HydrophobicContact CE1-CD1 4.1Å; Y317-L368 HydrophobicContact CE2-CB 4.29Å; Y317-L368 WeakPolarHBondContact OH-CB 3.26Å; Y317-N369 HydrophobicContact CE2-CB 4.37Å; Y317-N369 WeakPolarHBondContact CE2-ND2 3.47Å; Y317-N369 VanDerWaalsContact OH-CG 3.28Å; Y317-N369 PolarHBondContact OH-ND2 3.03Å; Y317-N369 VanDerWaalsContact OH-ND2 3.14Å; Y317-N369 PolarHBondContact OH-OD1 3.3Å; Y317-N369 VanDerWaalsContact OH-OD1 3.11Å; Y317-F416 HydrophobicContact CD1-CB 3.96Å; Y317-F416 HydrophobicContact CD1-CD1 4.47Å; Y317-F416 AromaticContact CD1-CD2 3.52Å; Y317-F416 HydrophobicContact CD1-CD2 3.52Å; Y317-F416 HydrophobicContact CD1-CE2 4.14Å; Y317-F416 AromaticContact CD1-CG 3.74Å; Y317-F416 HydrophobicContact CD1-CG 3.74Å; Y317-F416 AromaticContact CD2-CD2 3.94Å; Y317-F416 HydrophobicContact CD2-CD2 3.94Å; Y317-F416 AromaticContact CD2-CE2 3.85Å; Y317-F416 HydrophobicContact CD2-CE2 3.85Å; Y317-F416 HydrophobicContact CE1-CB 4.31Å; Y317-F416 HydrophobicContact CE1-CD2 4.05Å; Y317-F416 HydrophobicContact CE1-CG 4.42Å; Y317-F416 HydrophobicContact CE2-CD2 4.42Å; Y317-F416 AromaticContact CG-CD2 3.49Å; Y317-F416 HydrophobicContact CG-CD2 3.49Å; Y317-F416 VanDerWaalsContact CG-CD2 3.49Å; Y317-F416 AromaticContact CG-CE2 3.6Å; Y317-F416 HydrophobicContact CG-CE2 3.6Å; Y317-F416 HydrophobicContact CG-CG 4.02Å; Y317-F416 HydrophobicContact CG-CZ 4.18Å
318L98.3Very high97.8Very high1 Ų126.1 Ų26.11%0.00514%0.136CC..Hα-helixtrans-65.9-37.6178.3-74.2173.2000112.1L314 L320 H321 V324 L325 V361 T458 W467L314-L318 VanDerWaalsContact O-CB 3.32Å; L314-L318 WeakPolarHBondContact O-CB 3.38Å; L314-L318 WeakPolarHBondContact O-CG 3.04Å; L314-L318 PolarHBondContact O-N 3.42Å; L318-L320 VanDerWaalsContact C-N 3.3Å; L318-L320 PolarHBondContact O-N 3.42Å; L318-H321 CarbonylContact O-C 3.42Å; L318-H321 PolarHBondContact O-N 2.73Å; L318-V324 HydrophobicContact CD2-CB 4.35Å; L318-V324 HydrophobicContact CD2-CG1 3.8Å; L318-L325 HydrophobicContact CD2-CB 4.23Å; L318-V361 HydrophobicContact CD1-CG1 4.47Å; L318-V361 HydrophobicContact CD2-CG1 3.89Å; L318-V361 HydrophobicContact CG-CG1 4.25Å; L318-T458 HydrophobicContact CD1-CG2 3.98Å; L318-W467 HydrophobicContact CB-CH2 4.02Å; L318-W467 HydrophobicContact CB-CZ2 3.57Å; L318-W467 HydrophobicContact CD1-CH2 4.42Å
319G97.2Very high97.7Very high22 Ų2227.1 Ų27.123%0.22714%0.14CC..Hα-helixtrans-67.2-28.6174.400000113.8I315 A316 Y317I315-G319 PolarHBondContact O-N 3.36Å; A316-G319 PolarHBondContact O-N 3.07Å; Y317-G319 PolarHBondContact O-N 2.87Å
320L97.4Very high97.6Very high60 Ų6030.7 Ų30.731%0.31416%0.156SC..Hα-helixtrans-84-17.9174.5-69.5171.1000113.5A316 Y317 L318 L469 P473A316-L320 WeakPolarHBondContact O-CB 3.33Å; A316-L320 WeakPolarHBondContact O-CG 3.48Å; A316-L320 PolarHBondContact O-N 3.06Å; Y317-L320 PolarHBondContact O-N 2.9Å; L318-L320 VanDerWaalsContact C-N 3.3Å; L318-L320 PolarHBondContact O-N 3.42Å; L320-L469 HydrophobicContact CD1-CD1 4.38Å; L320-L469 HydrophobicContact CD2-CD1 3.9Å; L320-L469 HydrophobicContact CG-CD1 3.75Å; L320-P473 HydrophobicContact CD1-CB 4.02Å; L320-P473 HydrophobicContact CD1-CG 4.38Å; L320-P473 HydrophobicContact CD2-CB 4.22Å; L320-P473 HydrophobicContact CD2-CG 3.79Å
321H97.7Very high97.5Very high42 Ų4232 Ų3219%0.19416%0.162CC..  trans-129.171.7-175.2-55.777.1000110.9Y317 L318 H323 V324 L325 F416Y317-H321 WeakPolarHBondContact O-CB 3.31Å; Y317-H321 PolarHBondContact O-N 2.97Å; Y317-H321 PolarHBondContact O-ND1 3.15Å; L318-H321 CarbonylContact O-C 3.42Å; L318-H321 PolarHBondContact O-N 2.73Å; H321-H323 AromaticContact CD2-CE1 3.92Å; H321-H323 PolarHBondContact O-N 3.24Å; H321-H323 VanDerWaalsContact O-N 3.09Å; H321-V324 HydrophobicContact CB-CB 4.17Å; H321-V324 HydrophobicContact CB-CG2 3.9Å; H321-V324 WeakPolarHBondContact O-CB 3.32Å; H321-V324 PolarHBondContact O-N 3.4Å; H321-L325 PolarHBondContact O-N 3.03Å; H321-F416 HydrophobicContact CB-CD1 4.26Å; H321-F416 AromaticContact CG-CD1 3.81Å; H321-F416 AromaticContact ND1-CD1 3.78Å
322P95.7Very high97.2Very high90 Ų9032 Ų3258%0.58416%0.162SC*.Hα-helixtrans-55.8-31.2-177.5-2735.1000114.1V324 L325 H326P322-V324 VanDerWaalsContact C-N 3.31Å; P322-V324 PolarHBondContact O-N 2.89Å; P322-L325 PolarHBondContact O-N 2.85Å; P322-H326 WeakPolarHBondContact O-CB 3.2Å; P322-H326 PolarHBondContact O-N 2.83Å
323H97.1Very high96.8Very high112 Ų11236.5 Ų36.552%0.51918%0.182SC..Hα-helixtrans-64.7-32.6176.167.8-86000113.1H321 K327H321-H323 AromaticContact CD2-CE1 3.92Å; H321-H323 PolarHBondContact O-N 3.24Å; H321-H323 VanDerWaalsContact O-N 3.09Å; H323-K327 PolarHBondContact O-N 3.5Å
324V98.3Very high96.5Very high1 Ų140.6 Ų40.61%0.00621%0.21CC..Hα-helixtrans-71.3-44.6172.9176.30000109.8L318 H321 P322 H326 K327 V328 Y357 V361 F416 P418L318-V324 HydrophobicContact CD2-CB 4.35Å; L318-V324 HydrophobicContact CD2-CG1 3.8Å; H321-V324 HydrophobicContact CB-CB 4.17Å; H321-V324 HydrophobicContact CB-CG2 3.9Å; H321-V324 WeakPolarHBondContact O-CB 3.32Å; H321-V324 PolarHBondContact O-N 3.4Å; P322-V324 VanDerWaalsContact C-N 3.31Å; P322-V324 PolarHBondContact O-N 2.89Å; V324-H326 VanDerWaalsContact C-N 3.26Å; V324-H326 PolarHBondContact O-N 3.22Å; V324-K327 PolarHBondContact O-N 2.9Å; V324-V328 WeakPolarHBondContact O-CG2 3.18Å; V324-V328 PolarHBondContact O-N 3.34Å; V324-Y357 HydrophobicContact CG1-CE1 4.11Å; V324-V361 HydrophobicContact CG1-CG1 4.45Å; V324-V361 HydrophobicContact CG1-CG2 3.6Å; V324-F416 HydrophobicContact CB-CE1 4.42Å; V324-F416 HydrophobicContact CG1-CE1 4.08Å; V324-F416 HydrophobicContact CG2-CD1 4.34Å; V324-F416 HydrophobicContact CG2-CE1 4.16Å; V324-P418 HydrophobicContact CG1-CG 3.8Å; V324-P418 HydrophobicContact CG2-CG 4.19Å
325L97.4Very high96.1Very high12 Ų1244.2 Ų44.26%0.06323%0.227CC..Hα-helixtrans-58.8-40.6176179.559.6000111.3L318 H321 P322 V328 R329 A462 W467L318-L325 HydrophobicContact CD2-CB 4.23Å; H321-L325 PolarHBondContact O-N 3.03Å; P322-L325 PolarHBondContact O-N 2.85Å; L325-V328 WeakPolarHBondContact O-CB 3.44Å; L325-V328 PolarHBondContact O-N 3.46Å; L325-R329 WeakPolarHBondContact O-CG 3.4Å; L325-R329 PolarHBondContact O-N 3.47Å; L325-A462 HydrophobicContact CD1-CB 3.99Å; L325-W467 HydrophobicContact CD1-CH2 3.99Å; L325-W467 HydrophobicContact CD1-CZ3 4.39Å; L325-W467 HydrophobicContact CD2-CH2 3.86Å; L325-W467 HydrophobicContact CD2-CZ3 3.93Å
326H96.4Very high95.5Very high81 Ų8145.3 Ų45.338%0.37524%0.238SC..Hα-helixtrans-60.2-46.7174.3177.192.8000111.9P322 V324 V328 R329 E330 I499P322-H326 WeakPolarHBondContact O-CB 3.2Å; P322-H326 PolarHBondContact O-N 2.83Å; V324-H326 VanDerWaalsContact C-N 3.26Å; V324-H326 PolarHBondContact O-N 3.22Å; H326-V328 VanDerWaalsContact C-N 3.31Å; H326-V328 PolarHBondContact O-N 3.28Å; H326-R329 PolarHBondContact O-N 2.94Å; H326-R329 VanDerWaalsContact O-N 3.13Å; H326-E330 PolarHBondContact O-N 3.45Å; H326-I499 WeakPolarHBondContact CE1-CG2 3.42Å; H326-I499 PolarHBondContact CE1-OXT 2.88Å; H326-I499 VanDerWaalsContact ND1-CG2 3.31Å; H326-I499 WeakPolarHBondContact ND1-CG2 3.4Å; H326-I499 PolarHBondContact ND1-OXT 3.04Å
327K97.4Very high94.9Very high82 Ų8245.4 Ų45.436%0.35724%0.238SC..Hα-helixtrans-60.6-37.5173.9-74.9176.8173.4178.70113H323 V324 E330 E331 Y357 D419H323-K327 PolarHBondContact O-N 3.5Å; V324-K327 PolarHBondContact O-N 2.9Å; K327-E330 PolarHBondContact O-N 3.13Å; K327-E331 PolarHBondContact O-N 3.37Å; K327-Y357 HydrophobicContact CB-CD1 3.83Å; K327-Y357 HydrophobicContact CB-CE1 3.3Å; K327-Y357 HydrophobicContact CD-CE1 3.98Å; K327-Y357 HydrophobicContact CD-CE2 4.29Å; K327-Y357 VanDerWaalsContact CD-OH 3.26Å; K327-Y357 WeakPolarHBondContact CD-OH 3.35Å; K327-Y357 HydrophobicContact CG-CE1 4.31Å; K327-D419 IonicContact NZ-OD1 3.23Å; K327-D419 PolarHBondContact NZ-OD1 3.4Å; K327-D419 VanDerWaalsContact NZ-OD1 3.16Å; K327-D419 IonicContact NZ-OD2 2.58Å; K327-D419 PolarHBondContact NZ-OD2 2.87Å
328V97.4Very high93.9Very high0 Ų045.4 Ų45.40%024%0.241CC..Hα-helixtrans-62.7-45.5172.9169.70000110.6V324 L325 H326 E331 I332 Y357 V361 T458 A462V324-V328 WeakPolarHBondContact O-CG2 3.18Å; V324-V328 PolarHBondContact O-N 3.34Å; L325-V328 WeakPolarHBondContact O-CB 3.44Å; L325-V328 PolarHBondContact O-N 3.46Å; H326-V328 VanDerWaalsContact C-N 3.31Å; H326-V328 PolarHBondContact O-N 3.28Å; V328-E331 PolarHBondContact O-N 3.48Å; V328-I332 HydrophobicContact CG1-CD1 3.61Å; V328-I332 HydrophobicContact CG1-CG1 4.38Å; V328-I332 VanDerWaalsContact O-CG1 3.23Å; V328-I332 WeakPolarHBondContact O-CG1 3.32Å; V328-I332 PolarHBondContact O-N 2.93Å; V328-Y357 HydrophobicContact CG2-CD1 3.9Å; V328-Y357 HydrophobicContact CG2-CE1 4.05Å; V328-V361 HydrophobicContact CG2-CG2 3.75Å; V328-T458 HydrophobicContact CG1-CG2 4.19Å; V328-A462 HydrophobicContact CG1-CB 3.97Å
329R96.5Very high92.2Very high21 Ų2148.2 Ų48.28%0.07926%0.259CS..Hα-helixtrans-63.2-41.4176.9-71.7178.7171.2154.73.8112.1L325 H326 E331 I332 K333 L338 A462 C465 D466 F495 I499L325-R329 WeakPolarHBondContact O-CG 3.4Å; L325-R329 PolarHBondContact O-N 3.47Å; H326-R329 PolarHBondContact O-N 2.94Å; H326-R329 VanDerWaalsContact O-N 3.13Å; R329-E331 PolarHBondContact O-N 3.43Å; R329-I332 PolarHBondContact O-N 3.38Å; R329-K333 WeakPolarHBondContact O-CB 3.34Å; R329-K333 PolarHBondContact O-N 2.84Å; R329-L338 HydrophobicContact CB-CD1 4.01Å; R329-L338 HydrophobicContact CG-CD1 4.44Å; R329-L338 WeakPolarHBondContact O-CD1 3.4Å; R329-A462 HydrophobicContact CG-CB 4.08Å; R329-A462 PolarHBondContact NE-O 3.04Å; R329-C465 PolarHBondContact NH2-O 3.4Å; R329-D466 IonicContact CZ-OD1 2.88Å; R329-D466 VanDerWaalsContact CZ-OD1 3.23Å; R329-D466 IonicContact NH1-OD1 2.81Å; R329-D466 PolarHBondContact NH1-OD1 3.32Å; R329-D466 IonicContact NH2-OD1 2.6Å; R329-D466 PolarHBondContact NH2-OD1 2.75Å; R329-F495 VanDerWaalsContact NH1-CE2 3.33Å; R329-I499 HydrophobicContact CB-CD1 3.84Å; R329-I499 HydrophobicContact CB-CG1 4.21Å; R329-I499 HydrophobicContact CB-CG2 4.49Å
330E95.5Very high90.3Very high77 Ų7756.1 Ų56.136%0.3629%0.287SS..Hα-helixtrans-60.7-42.6174-78.2-64.4109.200112.1H326 K327 K333 S334 I499H326-E330 PolarHBondContact O-N 3.45Å; K327-E330 PolarHBondContact O-N 3.13Å; E330-K333 PolarHBondContact O-N 2.82Å; E330-K333 IonicContact OE1-NZ 3.59Å; E330-S334 PolarHBondContact O-N 3.5Å; E330-I499 HydrophobicContact CG-CG2 3.86Å; E330-I499 WeakPolarHBondContact OE1-CG2 3.45Å
331E95.2Very high88Confident28 Ų2858.3 Ų58.313%0.13131%0.308CS..Hα-helixtrans-60.1-49.2173.4179.2176.2-115.400111.3K327 V328 R329 K333 S334 Q335 L355 K356 Y357 T358K327-E331 PolarHBondContact O-N 3.37Å; V328-E331 PolarHBondContact O-N 3.48Å; R329-E331 PolarHBondContact O-N 3.43Å; E331-K333 VanDerWaalsContact C-N 3.33Å; E331-K333 PolarHBondContact O-N 3.4Å; E331-S334 WeakPolarHBondContact O-CB 3.42Å; E331-S334 PolarHBondContact O-N 3.5Å; E331-S334 PolarHBondContact O-OG 3.14Å; E331-Q335 PolarHBondContact O-N 3.22Å; E331-L355 HydrophobicContact CG-CD2 3.85Å; E331-L355 WeakPolarHBondContact OE2-CA 3.34Å; E331-K356 PolarHBondContact OE1-N 2.94Å; E331-Y357 WeakPolarHBondContact OE1-CB 3.35Å; E331-Y357 PolarHBondContact OE1-N 3.42Å; E331-Y357 PolarHBondContact OE2-N 2.86Å; E331-T358 WeakPolarHBondContact OE2-CB 3.47Å; E331-T358 PolarHBondContact OE2-N 3.44Å; E331-T358 PolarHBondContact OE2-OG1 3.25Å
332I92.8Very high85.6Confident0 Ų060 Ų600%032%0.319CS..Hα-helixtrans-63.4-38.2-180-67.9169.4000111.3V328 R329 Q335 G336 L337 L338 L355 V459 A462 R463V328-I332 HydrophobicContact CG1-CD1 3.61Å; V328-I332 HydrophobicContact CG1-CG1 4.38Å; V328-I332 VanDerWaalsContact O-CG1 3.23Å; V328-I332 WeakPolarHBondContact O-CG1 3.32Å; V328-I332 PolarHBondContact O-N 2.93Å; R329-I332 PolarHBondContact O-N 3.38Å; I332-Q335 PolarHBondContact O-N 3.31Å; I332-G336 PolarHBondContact O-N 2.88Å; I332-L337 HydrophobicContact CG2-CB 3.46Å; I332-L337 VanDerWaalsContact CG2-CB 3.46Å; I332-L337 HydrophobicContact CG2-CD1 4.09Å; I332-L337 HydrophobicContact CG2-CG 4.4Å; I332-L337 PolarHBondContact O-N 3.28Å; I332-L337 VanDerWaalsContact O-N 3.12Å; I332-L338 HydrophobicContact CB-CD1 4.17Å; I332-L338 HydrophobicContact CB-CG 4.49Å; I332-L338 HydrophobicContact CG2-CD1 3.97Å; I332-L338 HydrophobicContact CG2-CG 3.76Å; I332-L355 HydrophobicContact CG1-CD2 4.28Å; I332-V459 HydrophobicContact CD1-CB 4.26Å; I332-V459 HydrophobicContact CD1-CG1 4.25Å; I332-V459 HydrophobicContact CD1-CG2 4.02Å; I332-V459 HydrophobicContact CG1-CG2 4.29Å; I332-V459 HydrophobicContact CG2-CG1 4.49Å; I332-A462 HydrophobicContact CD1-CB 3.67Å; I332-R463 HydrophobicContact CG2-CG 3.96Å
333K91.3Very high83.3Confident97 Ų9765.3 Ų65.342%0.42234%0.335SS..Hα-helixtrans-63.2-43174179.6172.3166.1-167.80111.6R329 E330 E331 Q335 G336 L338 I499R329-K333 WeakPolarHBondContact O-CB 3.34Å; R329-K333 PolarHBondContact O-N 2.84Å; E330-K333 PolarHBondContact O-N 2.82Å; E330-K333 IonicContact OE1-NZ 3.59Å; E331-K333 VanDerWaalsContact C-N 3.33Å; E331-K333 PolarHBondContact O-N 3.4Å; K333-Q335 PolarHBondContact O-N 3.36Å; K333-G336 PolarHBondContact O-N 3.3Å; K333-L338 HydrophobicContact CB-CB 4.27Å; K333-L338 HydrophobicContact CB-CD1 4.05Å; K333-I499 HydrophobicContact CB-CD1 3.99Å; K333-I499 HydrophobicContact CD-CD1 3.53Å; K333-I499 HydrophobicContact CG-CD1 4.4Å
334S91Very high81Confident85 Ų8562.8 Ų62.859%0.59434%0.34SS*.Hα-helixtrans-60.9-27.1176.880.60000113.2E330 E331 G336E330-S334 PolarHBondContact O-N 3.5Å; E331-S334 WeakPolarHBondContact O-CB 3.42Å; E331-S334 PolarHBondContact O-N 3.5Å; E331-S334 PolarHBondContact O-OG 3.14Å; S334-G336 VanDerWaalsContact C-N 3.33Å
335Q89.4Confident79Confident77 Ų7764.1 Ų64.136%0.3635%0.349SS..THydrogen-bonded Turntrans-89.25.7174.8-58.2-54.4-56.700113.3E331 I332 K333 L337 T351 L355E331-Q335 PolarHBondContact O-N 3.22Å; I332-Q335 PolarHBondContact O-N 3.31Å; K333-Q335 PolarHBondContact O-N 3.36Å; Q335-L337 VanDerWaalsContact C-N 3.31Å; Q335-L337 HydrophobicContact CB-CD1 4.33Å; Q335-L337 HydrophobicContact CB-CG 4.26Å; Q335-L337 PolarHBondContact O-N 3.39Å; Q335-T351 HydrophobicContact CB-CG2 4.45Å; Q335-L355 HydrophobicContact CG-CD2 3.85Å
336G86.4Confident77.8Confident23 Ų2372.3 Ų72.324%0.23738%0.384CS..THydrogen-bonded Turntrans75.212.6177.100000115.3I332 K333 S334I332-G336 PolarHBondContact O-N 2.88Å; K333-G336 PolarHBondContact O-N 3.3Å; S334-G336 VanDerWaalsContact C-N 3.33Å
337L85.4Confident77.4Confident6 Ų669.2 Ų69.23%0.03137%0.371CS..THydrogen-bonded Turntrans-86.2-9.9-174.9-63175000113.8I332 Q335 L347 T351 V459 R463I332-L337 HydrophobicContact CG2-CB 3.46Å; I332-L337 VanDerWaalsContact CG2-CB 3.46Å; I332-L337 HydrophobicContact CG2-CD1 4.09Å; I332-L337 HydrophobicContact CG2-CG 4.4Å; I332-L337 PolarHBondContact O-N 3.28Å; I332-L337 VanDerWaalsContact O-N 3.12Å; Q335-L337 VanDerWaalsContact C-N 3.31Å; Q335-L337 HydrophobicContact CB-CD1 4.33Å; Q335-L337 HydrophobicContact CB-CG 4.26Å; Q335-L337 PolarHBondContact O-N 3.39Å; L337-L347 HydrophobicContact CD1-CD2 4.13Å; L337-T351 HydrophobicContact CD1-CG2 3.78Å; L337-T351 HydrophobicContact CD2-CG2 4.18Å; L337-T351 HydrophobicContact CG-CG2 4.24Å; L337-V459 HydrophobicContact CD1-CG1 4.26Å; L337-R463 PolarHBondContact O-NE 2.84Å; L337-R463 PolarHBondContact O-NH2 2.75Å
338L78.8Confident77Confident37 Ų3768.5 Ų68.519%0.19437%0.37CS..THydrogen-bonded Turntrans-1043.3178-81.9169000114.1R329 I332 K333 R463 F495 I499R329-L338 HydrophobicContact CB-CD1 4.01Å; R329-L338 HydrophobicContact CG-CD1 4.44Å; R329-L338 WeakPolarHBondContact O-CD1 3.4Å; I332-L338 HydrophobicContact CB-CD1 4.17Å; I332-L338 HydrophobicContact CB-CG 4.49Å; I332-L338 HydrophobicContact CG2-CD1 3.97Å; I332-L338 HydrophobicContact CG2-CG 3.76Å; K333-L338 HydrophobicContact CB-CB 4.27Å; K333-L338 HydrophobicContact CB-CD1 4.05Å; L338-R463 HydrophobicContact CD2-CB 4.2Å; L338-R463 HydrophobicContact CD2-CG 3.95Å; L338-R463 HydrophobicContact CG-CG 4.39Å; L338-F495 HydrophobicContact CD2-CD1 4.28Å; L338-F495 HydrophobicContact CD2-CE1 4.02Å; L338-I499 HydrophobicContact CD1-CD1 3.67Å
339C62.2Low76.8Confident59 Ų5969.2 Ų69.240%0.39937%0.374SS..  trans-82.6128.5-175.1-66.50000112.7S341 N342C339-S341 PolarHBondContact O-N 2.91Å; C339-S341 VanDerWaalsContact O-N 3.15Å; C339-N342 PolarHBondContact O-N 3.14Å
340K56.2Low76.6Confident188 Ų18870.6 Ų70.682%0.81739%0.39SS*.THydrogen-bonded Turntrans-57.9-25.6177.6-72.5-177.9179.2174.30114.4N342K340-N342 VanDerWaalsContact C-N 3.26Å; K340-N342 PolarHBondContact O-N 3.46Å
341S50.7Low76.4Confident106 Ų10668.4 Ų68.474%0.74138%0.382SS*.THydrogen-bonded Turntrans-75.7-11.5178.358.10000114C339C339-S341 PolarHBondContact O-N 2.91Å; C339-S341 VanDerWaalsContact O-N 3.15Å
342N46.3Very low76.3Confident79 Ų7967.3 Ų67.342%0.42238%0.377SS..  trans-116.256.8-177-87.2-4.5000111.6C339 K340 G344 S345C339-N342 PolarHBondContact O-N 3.14Å; K340-N342 VanDerWaalsContact C-N 3.26Å; K340-N342 PolarHBondContact O-N 3.46Å; N342-G344 PolarHBondContact O-N 3.36Å; N342-S345 PolarHBondContact O-N 2.92Å
343Q48.4Very low76.3Confident200 Ų20071.6 Ų71.694%0.93540%0.397SS*.THydrogen-bonded Turntrans-570.1161.2-74.8-175.83.800113.3
344G48.2Very low76.4Confident60 Ų6071.7 Ų71.762%0.61940%0.399SS*.THydrogen-bonded Turntrans-126.611.2177.300000116.7N342 K346N342-G344 PolarHBondContact O-N 3.36Å; G344-K346 VanDerWaalsContact C-N 3.32Å; G344-K346 PolarHBondContact O-N 3.14Å
345S56.8Low76.6Confident28 Ų2867.7 Ų67.720%0.19637%0.371CS..  trans-70.192.617364.80000109.5N342 L347N342-S345 PolarHBondContact O-N 2.92Å; S345-L347 PolarHBondContact O-N 3.35Å
346K71.6Confident76.9Confident185 Ų18570.7 Ų70.780%0.80438%0.383SS*.  trans-65128.1176.5-69.6-173.9178.1-176.60108.8G344 D348G344-K346 VanDerWaalsContact C-N 3.32Å; G344-K346 PolarHBondContact O-N 3.14Å; K346-D348 PolarHBondContact O-N 3.23Å
347L86.9Confident77.5Confident16 Ų1670.7 Ų70.78%0.08438%0.376CS..  trans-58.4131.2165.8-85.4162.9000108.6V153 L337 S345 L352 I456 V459 E460V153-L347 HydrophobicContact CG1-CB 3.88Å; V153-L347 WeakPolarHBondContact CG1-O 2.87Å; L337-L347 HydrophobicContact CD1-CD2 4.13Å; S345-L347 PolarHBondContact O-N 3.35Å; L347-L352 HydrophobicContact CD2-CD2 3.87Å; L347-L352 HydrophobicContact CD2-CG 4.3Å; L347-I456 HydrophobicContact CD1-CG2 4.16Å; L347-V459 HydrophobicContact CD1-CG1 4.1Å; L347-V459 HydrophobicContact CD2-CG1 4.16Å; L347-E460 HydrophobicContact CD1-CG 4.49Å; L347-E460 VanDerWaalsContact CD1-OE1 3.24Å; L347-E460 WeakPolarHBondContact CD1-OE1 3.48Å
348D90.3Very high78.1Confident66 Ų6670.4 Ų70.435%0.35337%0.374SS..  trans-133.5169.9173.370.34.2000110.6K346 A350 T351 L352K346-D348 PolarHBondContact O-N 3.23Å; D348-A350 VanDerWaalsContact C-N 3.27Å; D348-A350 PolarHBondContact O-N 3.35Å; D348-A350 PolarHBondContact OD1-N 3.36Å; D348-T351 PolarHBondContact O-N 3.28Å; D348-T351 WeakPolarHBondContact OD1-CB 3.33Å; D348-T351 PolarHBondContact OD1-N 2.56Å; D348-T351 PolarHBondContact OD1-OG1 3.19Å; D348-L352 WeakPolarHBondContact O-CB 3.5Å; D348-L352 VanDerWaalsContact O-CG 3.25Å; D348-L352 WeakPolarHBondContact O-CG 3.38Å; D348-L352 PolarHBondContact O-N 3.01Å
349M92.6Very high78.9Confident15 Ų1569.2 Ų69.27%0.07437%0.371CS..Hα-helixtrans-61-36.4-179.3-76.9-64-6600112.4L149 Q150 V153 L352 E353 V452L149-M349 HydrophobicContact CB-CE 4.28Å; L149-M349 HydrophobicContact CB-SD 4.2Å; Q150-M349 HydrophobicContact CB-CG 3.91Å; Q150-M349 HydrophobicContact CG-CG 4.35Å; V153-M349 HydrophobicContact CG2-CG 4.04Å; V153-M349 HydrophobicContact CG2-SD 3.89Å; M349-L352 PolarHBondContact O-N 2.82Å; M349-L352 HydrophobicContact SD-CD1 4.34Å; M349-E353 VanDerWaalsContact O-CG 3.25Å; M349-E353 WeakPolarHBondContact O-CG 3.32Å; M349-E353 PolarHBondContact O-N 2.87Å; M349-V452 HydrophobicContact CE-CG2 3.87Å; M349-V452 HydrophobicContact SD-CG1 4.17Å; M349-V452 HydrophobicContact SD-CG2 3.75Å
350A91.8Very high80.6Confident51 Ų5166.8 Ų66.842%0.42136%0.355SS..Hα-helixtrans-64.8-45.1-179.100000111.5D348 E353 Q354D348-A350 VanDerWaalsContact C-N 3.27Å; D348-A350 PolarHBondContact O-N 3.35Å; D348-A350 PolarHBondContact OD1-N 3.36Å; A350-E353 PolarHBondContact O-N 3.43Å; A350-Q354 PolarHBondContact O-N 3.38Å
351T91.5Very high82.6Confident31 Ų3157.8 Ų57.819%0.1932%0.316CS..Hα-helixtrans-64.1-46.3176.2-55.50000110.7Q335 L337 D348 E353 Q354 L355Q335-T351 HydrophobicContact CB-CG2 4.45Å; L337-T351 HydrophobicContact CD1-CG2 3.78Å; L337-T351 HydrophobicContact CD2-CG2 4.18Å; L337-T351 HydrophobicContact CG-CG2 4.24Å; D348-T351 PolarHBondContact O-N 3.28Å; D348-T351 WeakPolarHBondContact OD1-CB 3.33Å; D348-T351 PolarHBondContact OD1-N 2.56Å; D348-T351 PolarHBondContact OD1-OG1 3.19Å; T351-E353 PolarHBondContact O-N 3.25Å; T351-Q354 PolarHBondContact O-N 3.01Å; T351-L355 PolarHBondContact O-N 3.29Å
352L94.1Very high84.9Confident4 Ų453.1 Ų53.12%0.02128%0.282CS..Hα-helixtrans-58.8-34.3178.1-71.5172.4000112.4V153 L347 D348 M349 Q354 L355 V452 K455 I456V153-L352 HydrophobicContact CG1-CD1 4.24Å; V153-L352 HydrophobicContact CG2-CD1 3.96Å; L347-L352 HydrophobicContact CD2-CD2 3.87Å; L347-L352 HydrophobicContact CD2-CG 4.3Å; D348-L352 WeakPolarHBondContact O-CB 3.5Å; D348-L352 VanDerWaalsContact O-CG 3.25Å; D348-L352 WeakPolarHBondContact O-CG 3.38Å; D348-L352 PolarHBondContact O-N 3.01Å; M349-L352 PolarHBondContact O-N 2.82Å; M349-L352 HydrophobicContact SD-CD1 4.34Å; L352-Q354 VanDerWaalsContact C-N 3.32Å; L352-L355 HydrophobicContact CD2-CD1 4.25Å; L352-L355 PolarHBondContact O-N 3.38Å; L352-V452 HydrophobicContact CD1-CG1 4.02Å; L352-K455 HydrophobicContact CD2-CB 3.93Å; L352-K455 PolarHBondContact O-NZ 3.4Å; L352-I456 HydrophobicContact CD1-CD1 4.03Å; L352-I456 HydrophobicContact CD1-CG1 3.78Å; L352-I456 HydrophobicContact CD2-CG1 3.88Å; L352-I456 HydrophobicContact CG-CG1 4.47Å
353E92.8Very high87.3Confident91 Ų9153.5 Ų53.543%0.42528%0.28SS..Hα-helixtrans-66.9-30.9176.3-75.8173.7154.200113.1R146 M349 A350 T351 L355R146-E353 IonicContact CZ-OE1 3.38Å; R146-E353 IonicContact CZ-OE2 2.74Å; R146-E353 IonicContact NH1-OE1 2.66Å; R146-E353 PolarHBondContact NH1-OE1 2.97Å; R146-E353 IonicContact NH1-OE2 3.94Å; R146-E353 IonicContact NH2-OE1 3.61Å; R146-E353 IonicContact NH2-OE2 3.33Å; R146-E353 PolarHBondContact NH2-OE2 3.26Å; M349-E353 VanDerWaalsContact O-CG 3.25Å; M349-E353 WeakPolarHBondContact O-CG 3.32Å; M349-E353 PolarHBondContact O-N 2.87Å; A350-E353 PolarHBondContact O-N 3.43Å; T351-E353 PolarHBondContact O-N 3.25Å; E353-L355 VanDerWaalsContact C-N 3.34Å
354Q93.7Very high89.6Confident99 Ų9944 Ų4446%0.46324%0.235SC..Hα-helixtrans-76.3-18.1177.6-60.5-54.5-29.600113.9A350 T351 L352 K356A350-Q354 PolarHBondContact O-N 3.38Å; T351-Q354 PolarHBondContact O-N 3.01Å; L352-Q354 VanDerWaalsContact C-N 3.32Å; Q354-K356 VanDerWaalsContact C-N 3.25Å; Q354-K356 PolarHBondContact O-N 3.02Å
355L95.4Very high92Very high0 Ų041.1 Ų41.10%021%0.206CC..  trans-75.973.6177.4-57.3177.6000111.5E331 I332 Q335 T351 L352 E353 G359 K455 V459E331-L355 HydrophobicContact CG-CD2 3.85Å; E331-L355 WeakPolarHBondContact OE2-CA 3.34Å; I332-L355 HydrophobicContact CG1-CD2 4.28Å; Q335-L355 HydrophobicContact CG-CD2 3.85Å; T351-L355 PolarHBondContact O-N 3.29Å; L352-L355 HydrophobicContact CD2-CD1 4.25Å; L352-L355 PolarHBondContact O-N 3.38Å; E353-L355 VanDerWaalsContact C-N 3.34Å; L355-G359 PolarHBondContact O-N 2.92Å; L355-G359 VanDerWaalsContact O-N 3.15Å; L355-K455 PolarHBondContact O-NZ 3.13Å; L355-V459 HydrophobicContact CD1-CG2 3.31Å
356K95.6Very high93.9Very high140 Ų14040.2 Ų40.261%0.60920%0.199SC*.Hα-helixtrans-72.6-45.7-174.9-66.6178.4-172.71740111.6E331 Q354 G359 C360E331-K356 PolarHBondContact OE1-N 2.94Å; Q354-K356 VanDerWaalsContact C-N 3.25Å; Q354-K356 PolarHBondContact O-N 3.02Å; K356-G359 WeakPolarHBondContact O-CA 3.43Å; K356-G359 PolarHBondContact O-N 2.96Å; K356-C360 PolarHBondContact O-N 3.49Å; K356-C360 PolarHBondContact O-SG 2.96Å
357Y97.4Very high95Very high23 Ų2331.8 Ų31.89%0.0916%0.162CC..Hα-helixtrans-66.1-45.1179.1-169.7-108.2000111.3V324 K327 V328 E331 G359 C360 V361 P418 D419 I422V324-Y357 HydrophobicContact CG1-CE1 4.11Å; K327-Y357 HydrophobicContact CB-CD1 3.83Å; K327-Y357 HydrophobicContact CB-CE1 3.3Å; K327-Y357 HydrophobicContact CD-CE1 3.98Å; K327-Y357 HydrophobicContact CD-CE2 4.29Å; K327-Y357 VanDerWaalsContact CD-OH 3.26Å; K327-Y357 WeakPolarHBondContact CD-OH 3.35Å; K327-Y357 HydrophobicContact CG-CE1 4.31Å; V328-Y357 HydrophobicContact CG2-CD1 3.9Å; V328-Y357 HydrophobicContact CG2-CE1 4.05Å; E331-Y357 WeakPolarHBondContact OE1-CB 3.35Å; E331-Y357 PolarHBondContact OE1-N 3.42Å; E331-Y357 PolarHBondContact OE2-N 2.86Å; Y357-G359 PolarHBondContact O-N 3.43Å; Y357-C360 CarbonylContact O-C 3.53Å; Y357-C360 WeakPolarHBondContact O-CA 3.32Å; Y357-C360 VanDerWaalsContact O-CB 3.23Å; Y357-C360 WeakPolarHBondContact O-CB 3.45Å; Y357-C360 PolarHBondContact O-N 3.26Å; Y357-V361 HydrophobicContact CD1-CG2 4.17Å; Y357-V361 HydrophobicContact CE1-CG2 3.88Å; Y357-V361 WeakPolarHBondContact O-CG2 3.4Å; Y357-V361 PolarHBondContact O-N 3.04Å; Y357-P418 HydrophobicContact CE2-CB 4.15Å; Y357-D419 WeakPolarHBondContact CE2-OD1 3.47Å; Y357-D419 PolarHBondContact OH-OD1 3.08Å; Y357-I422 HydrophobicContact CD2-CD1 4Å; Y357-I422 HydrophobicContact CD2-CG1 4.26Å; Y357-I422 HydrophobicContact CE2-CD1 4Å
358T98.1Very high95.4Very high0 Ų032.8 Ų32.80%017%0.167CC..Hα-helixtrans-54.9-41.2171.1-560000111E331 C360 V361 I362 K455 T458E331-T358 WeakPolarHBondContact OE2-CB 3.47Å; E331-T358 PolarHBondContact OE2-N 3.44Å; E331-T358 PolarHBondContact OE2-OG1 3.25Å; T358-C360 VanDerWaalsContact C-N 3.31Å; T358-C360 PolarHBondContact O-N 3.5Å; T358-V361 PolarHBondContact O-N 3.07Å; T358-I362 HydrophobicContact CG2-CD1 4.37Å; T358-I362 WeakPolarHBondContact O-CG1 3.5Å; T358-I362 PolarHBondContact O-N 2.91Å; T358-I362 VanDerWaalsContact O-N 3.09Å; T358-K455 HydrophobicContact CG2-CG 4.38Å; T358-T458 HydrophobicContact CG2-CG2 3.82Å
359G97.3Very high95.6Very high13 Ų1330.5 Ų30.513%0.13416%0.155CC..Hα-helixtrans-60.4-35.7171.500000114L355 K356 Y357 K363L355-G359 PolarHBondContact O-N 2.92Å; L355-G359 VanDerWaalsContact O-N 3.15Å; K356-G359 WeakPolarHBondContact O-CA 3.43Å; K356-G359 PolarHBondContact O-N 2.96Å; Y357-G359 PolarHBondContact O-N 3.43Å; G359-K363 VanDerWaalsContact O-CG 3.31Å; G359-K363 WeakPolarHBondContact O-CG 3.45Å; G359-K363 PolarHBondContact O-N 3.27Å
360C96.9Very high95.8Very high7 Ų730 Ų305%0.04715%0.153CC..Hα-helixtrans-69.5-40.7175.7-620000112.1K356 Y357 T358 I362 K363 E364 P418 F421K356-C360 PolarHBondContact O-N 3.49Å; K356-C360 PolarHBondContact O-SG 2.96Å; Y357-C360 CarbonylContact O-C 3.53Å; Y357-C360 WeakPolarHBondContact O-CA 3.32Å; Y357-C360 VanDerWaalsContact O-CB 3.23Å; Y357-C360 WeakPolarHBondContact O-CB 3.45Å; Y357-C360 PolarHBondContact O-N 3.26Å; T358-C360 VanDerWaalsContact C-N 3.31Å; T358-C360 PolarHBondContact O-N 3.5Å; C360-I362 VanDerWaalsContact C-N 3.33Å; C360-I362 PolarHBondContact O-N 3.3Å; C360-K363 WeakPolarHBondContact O-CB 3.49Å; C360-K363 PolarHBondContact O-N 3.5Å; C360-E364 PolarHBondContact O-N 3.3Å; C360-P418 HydrophobicContact CB-CB 4.26Å; C360-P418 WeakPolarHBondContact CB-O 3.41Å; C360-F421 HydrophobicContact CB-CB 3.84Å; C360-F421 PolarHBondContact SG-O 3.09Å; C360-F421 VanDerWaalsContact SG-O 3.4Å
361V98.4Very high95.9Very high0 Ų028 Ų280%014%0.136CC..Hα-helixtrans-58.8-45.3174.4174.40000110.9L314 L318 V324 V328 Y357 T358 E364 T365 F416 P418L314-V361 HydrophobicContact CD2-CG1 3.95Å; L318-V361 HydrophobicContact CD1-CG1 4.47Å; L318-V361 HydrophobicContact CD2-CG1 3.89Å; L318-V361 HydrophobicContact CG-CG1 4.25Å; V324-V361 HydrophobicContact CG1-CG1 4.45Å; V324-V361 HydrophobicContact CG1-CG2 3.6Å; V328-V361 HydrophobicContact CG2-CG2 3.75Å; Y357-V361 HydrophobicContact CD1-CG2 4.17Å; Y357-V361 HydrophobicContact CE1-CG2 3.88Å; Y357-V361 WeakPolarHBondContact O-CG2 3.4Å; Y357-V361 PolarHBondContact O-N 3.04Å; T358-V361 PolarHBondContact O-N 3.07Å; V361-E364 PolarHBondContact O-N 3.38Å; V361-T365 WeakPolarHBondContact O-CB 3.44Å; V361-T365 PolarHBondContact O-N 2.78Å; V361-T365 PolarHBondContact O-OG1 2.83Å; V361-F416 HydrophobicContact CG1-CZ 4.05Å; V361-P418 HydrophobicContact CB-CG 4.42Å; V361-P418 HydrophobicContact CG2-CB 3.88Å; V361-P418 HydrophobicContact CG2-CG 3.84Å
362I98.4Very high96Very high7 Ų729.4 Ų29.44%0.03614%0.144CC..Hα-helixtrans-63.4-44.5175.9-65.3164.6000110.8L314 T358 C360 E364 T365 L366 L454 K455L314-I362 HydrophobicContact CD1-CG1 4.23Å; L314-I362 HydrophobicContact CD2-CG1 4.1Å; T358-I362 HydrophobicContact CG2-CD1 4.37Å; T358-I362 WeakPolarHBondContact O-CG1 3.5Å; T358-I362 PolarHBondContact O-N 2.91Å; T358-I362 VanDerWaalsContact O-N 3.09Å; C360-I362 VanDerWaalsContact C-N 3.33Å; C360-I362 PolarHBondContact O-N 3.3Å; I362-E364 PolarHBondContact O-N 2.78Å; I362-T365 PolarHBondContact O-N 2.71Å; I362-L366 HydrophobicContact CG2-CD1 3.99Å; I362-L366 HydrophobicContact CG2-CG 4.38Å; I362-L366 VanDerWaalsContact O-CG 3.3Å; I362-L366 WeakPolarHBondContact O-CG 3.36Å; I362-L366 PolarHBondContact O-N 3.33Å; I362-L454 HydrophobicContact CD1-CB 3.93Å; I362-L454 HydrophobicContact CG1-CB 4.29Å; I362-L454 HydrophobicContact CG2-CB 4.29Å; I362-L454 HydrophobicContact CG2-CD1 4Å; I362-K455 HydrophobicContact CD1-CB 4.21Å; I362-K455 HydrophobicContact CD1-CG 3.47Å; I362-K455 VanDerWaalsContact CD1-CG 3.47Å
363K96.6Very high95.9Very high87 Ų8731 Ų3138%0.37816%0.155SC..Hα-helixtrans-59.4-45.3176.9-75.6174.2-179.2177.60112G359 C360 T365 L366 R367 F421 F434G359-K363 VanDerWaalsContact O-CG 3.31Å; G359-K363 WeakPolarHBondContact O-CG 3.45Å; G359-K363 PolarHBondContact O-N 3.27Å; C360-K363 WeakPolarHBondContact O-CB 3.49Å; C360-K363 PolarHBondContact O-N 3.5Å; K363-T365 VanDerWaalsContact C-N 3.34Å; K363-L366 CarbonylContact O-C 3.55Å; K363-L366 PolarHBondContact O-N 2.83Å; K363-R367 PolarHBondContact O-N 2.91Å; K363-F421 HydrophobicContact CB-CD1 4.15Å; K363-F421 HydrophobicContact CB-CD2 3.68Å; K363-F421 HydrophobicContact CB-CE1 4.21Å; K363-F421 HydrophobicContact CB-CE2 3.75Å; K363-F421 HydrophobicContact CB-CG 3.88Å; K363-F421 HydrophobicContact CB-CZ 4.02Å; K363-F421 HydrophobicContact CD-CB 4.02Å; K363-F421 HydrophobicContact CD-CD1 3.76Å; K363-F421 HydrophobicContact CD-CE1 4.32Å; K363-F421 HydrophobicContact CD-CG 3.85Å; K363-F434 HydrophobicContact CB-CE1 4.23Å; K363-F434 HydrophobicContact CB-CZ 3.86Å; K363-F434 HydrophobicContact CG-CE1 3.97Å; K363-F434 HydrophobicContact CG-CZ 4.06Å; K363-F434 WeakPolarHBondContact O-CE2 3.41Å; K363-F434 WeakPolarHBondContact O-CZ 3.28Å
364E96.9Very high95.8Very high0 Ų027.4 Ų27.40%014%0.142CC..Hα-helixtrans-66.8-37.7179.7-174.667.1165.900112.2C360 V361 I362 L366 R367 L368 E415 F416 N417 P418 R420 F421C360-E364 PolarHBondContact O-N 3.3Å; V361-E364 PolarHBondContact O-N 3.38Å; I362-E364 PolarHBondContact O-N 2.78Å; E364-L366 PolarHBondContact O-N 2.95Å; E364-R367 WeakPolarHBondContact O-CB 3.47Å; E364-R367 PolarHBondContact O-N 3.29Å; E364-R367 IonicContact OE1-CZ 3.5Å; E364-R367 IonicContact OE1-NE 3.42Å; E364-R367 PolarHBondContact OE1-NE 2.96Å; E364-R367 IonicContact OE1-NH2 2.71Å; E364-R367 PolarHBondContact OE1-NH2 2.79Å; E364-R367 WeakPolarHBondContact OE2-CD 3.46Å; E364-R367 IonicContact OE2-CZ 2.85Å; E364-R367 IonicContact OE2-NE 3.7Å; E364-R367 PolarHBondContact OE2-NE 3.11Å; E364-R367 IonicContact OE2-NH2 3.18Å; E364-L368 HydrophobicContact CG-CD1 4.26Å; E364-L368 PolarHBondContact O-N 3.17Å; E364-L368 VanDerWaalsContact O-N 3.09Å; E364-E415 VanDerWaalsContact OE1-O 3.09Å; E364-F416 HydrophobicContact CB-CD2 4.39Å; E364-F416 HydrophobicContact CB-CE2 3.99Å; E364-F416 HydrophobicContact CG-CD2 3.62Å; E364-F416 HydrophobicContact CG-CE2 3.74Å; E364-F416 HydrophobicContact CG-CG 4.3Å; E364-N417 PolarHBondContact OE1-N 3.09Å; E364-N417 VanDerWaalsContact OE1-N 3.08Å; E364-P418 HydrophobicContact CB-CG 4.41Å; E364-R420 IonicContact OE1-CZ 3.93Å; E364-R420 IonicContact OE1-NE 2.72Å; E364-R420 PolarHBondContact OE1-NE 2.77Å; E364-R420 IonicContact OE1-NH2 3.22Å; E364-R420 VanDerWaalsContact OE2-CD 3.29Å; E364-R420 WeakPolarHBondContact OE2-CD 3.26Å; E364-R420 IonicContact OE2-NE 3.24Å; E364-R420 PolarHBondContact OE2-NE 3.44Å; E364-F421 HydrophobicContact CB-CD2 4.2Å; E364-F421 HydrophobicContact CB-CE2 4.02Å; E364-F421 VanDerWaalsContact OE2-CE2 3.27Å; E364-F421 WeakPolarHBondContact OE2-CE2 3.39Å
365T97.9Very high95.8Very high1 Ų123.1 Ų23.11%0.00612%0.124CC..Hα-helixtrans-60-47.7172.8-60.30000111.3L314 Y317 V361 I362 K363 R367 L368 N369L314-T365 HydrophobicContact CD2-CG2 4.21Å; L314-T365 VanDerWaalsContact CD2-OG1 3.29Å; L314-T365 WeakPolarHBondContact CD2-OG1 3.47Å; L314-T365 HydrophobicContact CG-CG2 3.99Å; Y317-T365 HydrophobicContact CD2-CG2 3.94Å; Y317-T365 HydrophobicContact CE2-CG2 4.25Å; V361-T365 WeakPolarHBondContact O-CB 3.44Å; V361-T365 PolarHBondContact O-N 2.78Å; V361-T365 PolarHBondContact O-OG1 2.83Å; I362-T365 PolarHBondContact O-N 2.71Å; K363-T365 VanDerWaalsContact C-N 3.34Å; T365-R367 VanDerWaalsContact C-N 3.29Å; T365-R367 PolarHBondContact O-N 3.43Å; T365-L368 PolarHBondContact O-N 2.83Å; T365-N369 CarbonylContact O-C 3.48Å; T365-N369 PolarHBondContact O-N 3.42Å
366L97Very high95.6Very high8 Ų826.5 Ų26.54%0.04214%0.139CC..Hα-helixtrans-71.2-21.7178-65.2177.2000113.2A310 I362 K363 E364 P370 P371 F434 P436 F437A310-L366 HydrophobicContact CB-CD2 3.93Å; I362-L366 HydrophobicContact CG2-CD1 3.99Å; I362-L366 HydrophobicContact CG2-CG 4.38Å; I362-L366 VanDerWaalsContact O-CG 3.3Å; I362-L366 WeakPolarHBondContact O-CG 3.36Å; I362-L366 PolarHBondContact O-N 3.33Å; K363-L366 CarbonylContact O-C 3.55Å; K363-L366 PolarHBondContact O-N 2.83Å; E364-L366 PolarHBondContact O-N 2.95Å; L366-P370 WeakPolarHBondContact O-CA 3.04Å; L366-P370 WeakPolarHBondContact O-CB 3.3Å; L366-P370 WeakPolarHBondContact O-CD 3.06Å; L366-P371 HydrophobicContact CD2-CG 4.08Å; L366-F434 HydrophobicContact CB-CZ 4.45Å; L366-P436 HydrophobicContact CB-CB 3.76Å; L366-P436 HydrophobicContact CB-CG 4.26Å; L366-P436 HydrophobicContact CD1-CB 4.29Å; L366-P436 HydrophobicContact CD1-CG 4.38Å; L366-F437 HydrophobicContact CD1-CE2 3.83Å; L366-F437 HydrophobicContact CD1-CZ 3.75Å
367R95.4Very high95.6Very high8 Ų820.4 Ų20.43%0.0311%0.112CC..Hα-helixtrans-68.8-51.9173.3-171-169.462.680.6-3.3110.1K363 E364 T365 H404 F410 K413 E415 F421 F434K363-R367 PolarHBondContact O-N 2.91Å; E364-R367 WeakPolarHBondContact O-CB 3.47Å; E364-R367 PolarHBondContact O-N 3.29Å; E364-R367 IonicContact OE1-CZ 3.5Å; E364-R367 IonicContact OE1-NE 3.42Å; E364-R367 PolarHBondContact OE1-NE 2.96Å; E364-R367 IonicContact OE1-NH2 2.71Å; E364-R367 PolarHBondContact OE1-NH2 2.79Å; E364-R367 WeakPolarHBondContact OE2-CD 3.46Å; E364-R367 IonicContact OE2-CZ 2.85Å; E364-R367 IonicContact OE2-NE 3.7Å; E364-R367 PolarHBondContact OE2-NE 3.11Å; E364-R367 IonicContact OE2-NH2 3.18Å; T365-R367 VanDerWaalsContact C-N 3.29Å; T365-R367 PolarHBondContact O-N 3.43Å; R367-H404 HydrophobicContact CG-CB 4.04Å; R367-H404 PolarHBondContact O-ND1 3.36Å; R367-F410 HydrophobicContact CG-CE2 4.17Å; R367-F410 HydrophobicContact CG-CZ 4.33Å; R367-K413 VanDerWaalsContact CZ-O 3.29Å; R367-K413 PolarHBondContact NH1-O 2.97Å; R367-K413 PolarHBondContact NH2-O 3.13Å; R367-E415 PolarHBondContact NH2-O 2.74Å; R367-F421 HydrophobicContact CB-CZ 4.42Å; R367-F434 HydrophobicContact CB-CD2 4.24Å; R367-F434 HydrophobicContact CB-CE2 3.8Å; R367-F434 HydrophobicContact CG-CD2 4.34Å; R367-F434 HydrophobicContact CG-CE2 4.39Å
368L94.4Very high95.5Very high37 Ų3720.4 Ų20.419%0.19412%0.115CC..Hα-helixtrans-76-45.9-175.5-74.6165.2000112.6Y317 E364 T365 P370 K413 F416Y317-L368 HydrophobicContact CE1-CD1 4.1Å; Y317-L368 HydrophobicContact CE2-CB 4.29Å; Y317-L368 WeakPolarHBondContact OH-CB 3.26Å; E364-L368 HydrophobicContact CG-CD1 4.26Å; E364-L368 PolarHBondContact O-N 3.17Å; E364-L368 VanDerWaalsContact O-N 3.09Å; T365-L368 PolarHBondContact O-N 2.83Å; L368-P370 VanDerWaalsContact C-CD 3.42Å; L368-P370 WeakPolarHBondContact O-CD 3.08Å; L368-K413 VanDerWaalsContact CD2-O 3.27Å; L368-K413 WeakPolarHBondContact CD2-O 3.25Å; L368-F416 HydrophobicContact CD1-CB 4.1Å; L368-F416 HydrophobicContact CD1-CD2 3.75Å; L368-F416 HydrophobicContact CD1-CG 4.44Å
369N95.7Very high95.5Very high19 Ų1920.6 Ų20.610%0.10212%0.116CC..SBendtrans-122.667.6-179.3-67.5-7.4000110.4S313 Y317 T365 P371 V482S313-N369 PolarHBondContact OG-ND2 3.47Å; Y317-N369 HydrophobicContact CE2-CB 4.37Å; Y317-N369 WeakPolarHBondContact CE2-ND2 3.47Å; Y317-N369 VanDerWaalsContact OH-CG 3.28Å; Y317-N369 PolarHBondContact OH-ND2 3.03Å; Y317-N369 VanDerWaalsContact OH-ND2 3.14Å; Y317-N369 PolarHBondContact OH-OD1 3.3Å; Y317-N369 VanDerWaalsContact OH-OD1 3.11Å; T365-N369 CarbonylContact O-C 3.48Å; T365-N369 PolarHBondContact O-N 3.42Å; N369-P371 WeakPolarHBondContact O-CD 3.44Å; N369-V482 HydrophobicContact CB-CG1 4.04Å
370P95.5Very high95.5Very high3 Ų323.3 Ų23.32%0.01913%0.127CC..  trans-62.7123.5173.125.7-31.8000108.9L366 L368 V372 I400 C401 V482L366-P370 WeakPolarHBondContact O-CA 3.04Å; L366-P370 WeakPolarHBondContact O-CB 3.3Å; L366-P370 WeakPolarHBondContact O-CD 3.06Å; L368-P370 VanDerWaalsContact C-CD 3.42Å; L368-P370 WeakPolarHBondContact O-CD 3.08Å; P370-V372 PolarHBondContact O-N 3.23Å; P370-V372 VanDerWaalsContact O-N 3.12Å; P370-I400 HydrophobicContact CB-CG2 3.99Å; P370-I400 HydrophobicContact CG-CG2 4.23Å; P370-C401 HydrophobicContact CG-CB 3.83Å; P370-V482 WeakPolarHBondContact O-CG2 3.5Å
371P95.9Very high95.5Very high10 Ų1027.9 Ų27.97%0.06515%0.146CC..SBendtrans-53.9-38.4-176.8-31.537000113.1T306 A310 L366 N369 T481 V482T306-P371 HydrophobicContact CG2-CB 4.45Å; T306-P371 WeakPolarHBondContact O-CB 3.5Å; T306-P371 VanDerWaalsContact O-CG 3.24Å; T306-P371 WeakPolarHBondContact O-CG 3.27Å; A310-P371 HydrophobicContact CB-CG 3.87Å; L366-P371 HydrophobicContact CD2-CG 4.08Å; N369-P371 WeakPolarHBondContact O-CD 3.44Å; P371-T481 WeakPolarHBondContact O-CA 3.47Å; P371-V482 PolarHBondContact O-N 2.82Å
372V93.5Very high95.5Very high61 Ų6129.4 Ų29.437%0.3716%0.156SC..SBendtrans-106.2114.9173.5179.30000108.8T306 P370 G374T306-V372 HydrophobicContact CG2-CG2 3.9Å; P370-V372 PolarHBondContact O-N 3.23Å; P370-V372 VanDerWaalsContact O-N 3.12Å; V372-G374 VanDerWaalsContact C-N 3.26Å; V372-G374 VanDerWaalsContact CG1-O 3.28Å; V372-G374 WeakPolarHBondContact CG1-O 3.18Å; V372-G374 PolarHBondContact O-N 2.97Å
373P90.4Very high95.5Very high38 Ų3829.8 Ų29.825%0.24716%0.157CC..  trans-75.2-12.6-173.233.1-41000113.8S399 I400 C401 T478P373-S399 CarbonylContact O-C 3.44Å; P373-I400 PolarHBondContact O-N 3.13Å; P373-C401 PolarHBondContact O-N 2.69Å; P373-T478 HydrophobicContact CB-CG2 4.24Å; P373-T478 HydrophobicContact CG-CG2 3.67Å
374G92.3Very high95.6Very high15 Ų1531.3 Ų31.316%0.15517%0.165CC..EExtended strand (participates in β ladder)trans164.3-173.4-173.400000111.9V372 Y398V372-G374 VanDerWaalsContact C-N 3.26Å; V372-G374 VanDerWaalsContact CG1-O 3.28Å; V372-G374 WeakPolarHBondContact CG1-O 3.18Å; V372-G374 PolarHBondContact O-N 2.97Å; G374-Y398 VanDerWaalsContact CA-O 3.22Å; G374-Y398 WeakPolarHBondContact CA-O 3.38Å
375G91.9Very high95.6Very high8 Ų831.6 Ų31.68%0.08217%0.167CC..EExtended strand (participates in β ladder)trans-143.6153.4-177.200000114.2I397 Y398G375-I397 WeakPolarHBondContact O-CA 3.14Å; G375-Y398 VanDerWaalsContact CA-CE1 3.42Å; G375-Y398 PolarHBondContact N-O 3.3Å; G375-Y398 VanDerWaalsContact N-O 3.15Å; G375-Y398 VanDerWaalsContact O-CD1 3.28Å; G375-Y398 WeakPolarHBondContact O-CD1 3.45Å; G375-Y398 WeakPolarHBondContact O-CE1 3.49Å; G375-Y398 PolarHBondContact O-N 2.83Å
376F91.9Very high95.5Very high71 Ų7135.7 Ų35.731%0.31119%0.189SC..EExtended strand (participates in β ladder)trans-89.8136.7178.2-57.9-86.5000111F84 I397F84-F376 HydrophobicContact CE2-CE1 4.21Å; F376-I397 HydrophobicContact CD1-CD1 3.8Å; F376-I397 HydrophobicContact CD1-CG1 3.76Å; F376-I397 HydrophobicContact CE1-CD1 3.61Å; F376-I397 HydrophobicContact CE1-CG1 4.07Å
377R95.5Very high95.4Very high13 Ų1336.9 Ų36.95%0.04920%0.203CC..EExtended strand (participates in β ladder)trans-138161.5176.9-66.7-62178.6-83.13.5109.9I100 E104 V108 A109 N395 V396 Y398I100-R377 HydrophobicContact CG2-CG 4.22Å; E104-R377 WeakPolarHBondContact OE2-CD 3.32Å; E104-R377 IonicContact OE2-CZ 3.32Å; E104-R377 IonicContact OE2-NE 2.87Å; E104-R377 PolarHBondContact OE2-NE 3.46Å; E104-R377 IonicContact OE2-NH2 2.91Å; V108-R377 HydrophobicContact CB-CB 4.04Å; V108-R377 HydrophobicContact CB-CG 4.35Å; V108-R377 HydrophobicContact CG1-CB 4.42Å; V108-R377 HydrophobicContact CG2-CB 4.41Å; V108-R377 HydrophobicContact CG2-CG 4.17Å; A109-R377 VanDerWaalsContact C-CD 3.45Å; A109-R377 CarbonylContact O-C 3.47Å; A109-R377 WeakPolarHBondContact O-CA 3.31Å; A109-R377 WeakPolarHBondContact O-CD 3.4Å; R377-N395 CarbonylContact O-C 3.59Å; R377-N395 WeakPolarHBondContact O-CA 3.45Å; R377-V396 WeakPolarHBondContact CA-O 3.45Å; R377-V396 HydrophobicContact CB-CB 4.04Å; R377-V396 WeakPolarHBondContact CB-O 3.35Å; R377-V396 PolarHBondContact N-O 2.65Å; R377-V396 PolarHBondContact O-N 3.02Å; R377-Y398 HydrophobicContact CG-CD1 4.32Å; R377-Y398 HydrophobicContact CG-CE1 4.43Å
378V96.6Very high95.5Very high23 Ų2339.6 Ų39.614%0.13921%0.214CC..EExtended strand (participates in β ladder)trans-124138.1166.864.80000109.5V108 A109 Q111 L380 W394V108-V378 CarbonylContact C-O 3.59Å; V108-V378 WeakPolarHBondContact CA-O 3.47Å; A109-V378 HydrophobicContact CB-CG1 4.41Å; A109-V378 PolarHBondContact N-O 2.94Å; A109-V378 PolarHBondContact O-N 2.84Å; Q111-V378 HydrophobicContact CB-CB 4.33Å; Q111-V378 HydrophobicContact CB-CG1 4.13Å; V378-L380 PolarHBondContact O-N 3.26Å; V378-W394 WeakPolarHBondContact CA-O 3.35Å
379A97.9Very high95.7Very high3 Ų337.9 Ų37.93%0.02521%0.205CC..EExtended strand (participates in β ladder)trans-71.8121.3176.300000110.8F383 I390 P391 G393 W394A379-F383 HydrophobicContact CB-CE1 4.01Å; A379-I390 HydrophobicContact CB-CG2 4.11Å; A379-P391 VanDerWaalsContact CB-O 3.31Å; A379-P391 WeakPolarHBondContact CB-O 3.39Å; A379-G393 PolarHBondContact O-N 3.02Å; A379-W394 PolarHBondContact N-O 3.34Å
380L97.2Very high95.8Very high70 Ų7037 Ų3737%0.36620%0.2SC..SBendtrans-79.8-25.6-179.8-63177.3000112.4L107 A109 V378 K392L107-L380 PolarHBondContact O-N 3.02Å; A109-L380 HydrophobicContact CB-CD1 4.15Å; A109-L380 HydrophobicContact CB-CD2 3.86Å; A109-L380 HydrophobicContact CB-CG 4.2Å; V378-L380 PolarHBondContact O-N 3.26Å; L380-K392 WeakPolarHBondContact O-CD 3.42Å; L380-K392 WeakPolarHBondContact O-CE 3.31Å; L380-K392 WeakPolarHBondContact O-CG 3.39Å
381K97.2Very high95.9Very high103 Ų10336.9 Ų36.945%0.44820%0.199SC..SBendtrans-148.6166175.460.2177.6178.6176.90109.6R106 F383R106-K381 WeakPolarHBondContact O-CE 3.32Å; K381-F383 WeakPolarHBondContact O-CD1 3.32Å
382T98.1Very high95.9Very high33 Ų3343.3 Ų43.320%0.20223%0.226CC..  trans-68.5132.8168.6-540000109.5D37 C40 Q389 I390 K392D37-T382 HydrophobicContact CB-CG2 3.67Å; D37-T382 WeakPolarHBondContact CB-OG1 3.34Å; D37-T382 WeakPolarHBondContact OD2-CB 3.33Å; D37-T382 WeakPolarHBondContact OD2-CG2 3.4Å; D37-T382 PolarHBondContact OD2-OG1 2.87Å; C40-T382 HydrophobicContact CB-CG2 4.22Å; T382-Q389 HydrophobicContact CG2-CB 4.14Å; T382-I390 VanDerWaalsContact CA-O 3.23Å; T382-I390 WeakPolarHBondContact CA-O 3.48Å; T382-K392 PolarHBondContact OG1-N 3.37Å
383F98.1Very high96Very high14 Ų1442.6 Ų42.66%0.06123%0.231CC..EExtended strand (participates in β ladder)trans-145.6158.8175.264.4-88.1000111.9I100 L107 V108 A379 K381 L385 I390I100-F383 HydrophobicContact CD1-CE2 3.93Å; I100-F383 HydrophobicContact CD1-CZ 3.73Å; L107-F383 HydrophobicContact CB-CD1 4.1Å; L107-F383 HydrophobicContact CB-CE1 4.11Å; L107-F383 HydrophobicContact CB-CG 4.43Å; L107-F383 HydrophobicContact CB-CZ 4.43Å; L107-F383 HydrophobicContact CD1-CD2 4.29Å; L107-F383 HydrophobicContact CD2-CB 4.05Å; L107-F383 HydrophobicContact CD2-CD1 4.42Å; L107-F383 HydrophobicContact CD2-CG 4.17Å; V108-F383 HydrophobicContact CG1-CE1 3.98Å; V108-F383 HydrophobicContact CG1-CZ 3.98Å; A379-F383 HydrophobicContact CB-CE1 4.01Å; K381-F383 WeakPolarHBondContact O-CD1 3.32Å; F383-L385 HydrophobicContact CD2-CB 4.36Å; F383-L385 HydrophobicContact CE2-CB 4.04Å; F383-L385 HydrophobicContact CE2-CD2 4.43Å; F383-I390 HydrophobicContact CD1-CB 4.19Å; F383-I390 HydrophobicContact CD2-CB 4.35Å; F383-I390 HydrophobicContact CD2-CG1 4.17Å; F383-I390 HydrophobicContact CE1-CB 3.83Å; F383-I390 HydrophobicContact CE1-CG1 4.41Å; F383-I390 HydrophobicContact CE1-CG2 3.87Å; F383-I390 HydrophobicContact CE2-CB 4.01Å; F383-I390 HydrophobicContact CE2-CG1 3.68Å; F383-I390 HydrophobicContact CG-CB 4.43Å; F383-I390 HydrophobicContact CZ-CB 3.73Å; F383-I390 HydrophobicContact CZ-CG1 3.82Å; F383-I390 HydrophobicContact CZ-CG2 3.8Å; F383-I390 PolarHBondContact N-O 3.41Å; F383-I390 VanDerWaalsContact N-O 3.16Å; F383-I390 PolarHBondContact O-N 2.67Å
384E97.4Very high96.3Very high119 Ų11941 Ų4156%0.55622%0.22SC*.EExtended strand (participates in β ladder)trans-80.7134.3173.3177.5176.7168.500111.6L42 Y388L42-E384 HydrophobicContact CD1-CB 3.66Å; L42-E384 HydrophobicContact CD1-CG 3.45Å; L42-E384 VanDerWaalsContact CD1-CG 3.45Å; E384-Y388 CarbonylContact C-O 3.54Å; E384-Y388 WeakPolarHBondContact CA-O 3.5Å
385L97.4Very high96.5Very high7 Ų741.3 Ų41.34%0.03722%0.218CC..EExtended strand (participates in β ladder)trans-143.1122.1168.9-17167.9000109.7I78 V91 N96 R99 I100 F383 G387 Y388 I390I78-L385 HydrophobicContact CD1-CB 4.2Å; I78-L385 HydrophobicContact CD1-CD2 3.84Å; I78-L385 HydrophobicContact CD1-CG 4.01Å; V91-L385 HydrophobicContact CG1-CD2 3.96Å; V91-L385 HydrophobicContact CG2-CD2 3.91Å; N96-L385 HydrophobicContact CB-CD1 4.44Å; R99-L385 HydrophobicContact CB-CD1 3.82Å; R99-L385 HydrophobicContact CG-CD1 3.73Å; I100-L385 HydrophobicContact CD1-CD2 3.88Å; I100-L385 HydrophobicContact CG1-CD2 4.11Å; F383-L385 HydrophobicContact CD2-CB 4.36Å; F383-L385 HydrophobicContact CE2-CB 4.04Å; F383-L385 HydrophobicContact CE2-CD2 4.43Å; L385-G387 VanDerWaalsContact C-N 3.28Å; L385-G387 PolarHBondContact O-N 3.39Å; L385-Y388 PolarHBondContact N-O 2.87Å; L385-Y388 PolarHBondContact O-N 3.48Å; L385-I390 HydrophobicContact CB-CD1 4.05Å; L385-I390 HydrophobicContact CB-CG1 3.72Å; L385-I390 HydrophobicContact CD2-CD1 4.43Å; L385-I390 HydrophobicContact CD2-CG1 4.32Å
386N95.3Very high96.7Very high86 Ų8641 Ų4146%0.4621%0.214SC..THydrogen-bonded Turntrans52.841.4178.2-159.534.8000113.7I78 Y388I78-N386 HydrophobicContact CD1-CB 4.34Å; I78-N386 HydrophobicContact CG2-CB 4.15Å; I78-N386 WeakPolarHBondContact CG2-ND2 3.44Å; N386-Y388 VanDerWaalsContact C-N 3.29Å; N386-Y388 WeakPolarHBondContact O-CD2 3.36Å; N386-Y388 VanDerWaalsContact O-CE2 3.3Å; N386-Y388 WeakPolarHBondContact O-CE2 3.41Å; N386-Y388 PolarHBondContact O-N 3.33Å
387G96.4Very high96.9Very high34 Ų3438 Ų3835%0.35120%0.202SC..THydrogen-bonded Turntrans75.97.7-178.100000115.5L385L385-G387 VanDerWaalsContact C-N 3.28Å; L385-G387 PolarHBondContact O-N 3.39Å
388Y97.8Very high96.9Very high65 Ų6538.2 Ų38.226%0.25520%0.203SC..EExtended strand (participates in β ladder)trans-118.8152.8178.3-58.9-76.1000111.9P43 L44 P45 I78 E384 L385 N386P43-Y388 HydrophobicContact CG-CD1 3.92Å; P43-Y388 HydrophobicContact CG-CE1 4.14Å; P43-Y388 WeakPolarHBondContact O-CA 3.32Å; L44-Y388 WeakPolarHBondContact O-CD1 3.38Å; P45-Y388 HydrophobicContact CB-CG 4.28Å; P45-Y388 HydrophobicContact CG-CG 4.15Å; I78-Y388 HydrophobicContact CD1-CD2 4.4Å; I78-Y388 HydrophobicContact CG2-CD2 3.62Å; I78-Y388 HydrophobicContact CG2-CE2 3.62Å; E384-Y388 CarbonylContact C-O 3.54Å; E384-Y388 WeakPolarHBondContact CA-O 3.5Å; L385-Y388 PolarHBondContact N-O 2.87Å; L385-Y388 PolarHBondContact O-N 3.48Å; N386-Y388 VanDerWaalsContact C-N 3.29Å; N386-Y388 WeakPolarHBondContact O-CD2 3.36Å; N386-Y388 VanDerWaalsContact O-CE2 3.3Å; N386-Y388 WeakPolarHBondContact O-CE2 3.41Å; N386-Y388 PolarHBondContact O-N 3.33Å
389Q97.4Very high96.9Very high0 Ų037.1 Ų37.10%020%0.196CC..EExtended strand (participates in β ladder)trans-79.8134.5166.964.9168.7-88.400111R36 D37 C40 L42 P43 L44 P45 T382 P391R36-Q389 VanDerWaalsContact CG-CD 3.44Å; D37-Q389 PolarHBondContact O-NE2 3.19Å; D37-Q389 PolarHBondContact O-OE1 2.7Å; C40-Q389 HydrophobicContact CB-CB 4.33Å; C40-Q389 PolarHBondContact O-NE2 2.95Å; L42-Q389 HydrophobicContact CB-CB 4.21Å; L42-Q389 WeakPolarHBondContact O-CG 3.31Å; L42-Q389 PolarHBondContact O-NE2 2.93Å; P43-Q389 PolarHBondContact O-N 3.28Å; L44-Q389 HydrophobicContact CD2-CG 4.1Å; P45-Q389 WeakPolarHBondContact CD-O 3.43Å; T382-Q389 HydrophobicContact CG2-CB 4.14Å; Q389-P391 WeakPolarHBondContact O-CD 3.46Å
390I98Very high96.7Very high0 Ų037.2 Ų37.20%020%0.196CC..EExtended strand (participates in β ladder)trans-102.9103165.5-48.3-49.2000106.8P45 I78 V89 A379 T382 F383 L385 V396P45-I390 HydrophobicContact CG-CD1 4Å; I78-I390 HydrophobicContact CD1-CD1 3.95Å; V89-I390 HydrophobicContact CG1-CD1 3.99Å; V89-I390 HydrophobicContact CG2-CD1 4.2Å; V89-I390 HydrophobicContact CG2-CG2 4.3Å; A379-I390 HydrophobicContact CB-CG2 4.11Å; T382-I390 VanDerWaalsContact CA-O 3.23Å; T382-I390 WeakPolarHBondContact CA-O 3.48Å; F383-I390 HydrophobicContact CD1-CB 4.19Å; F383-I390 HydrophobicContact CD2-CB 4.35Å; F383-I390 HydrophobicContact CD2-CG1 4.17Å; F383-I390 HydrophobicContact CE1-CB 3.83Å; F383-I390 HydrophobicContact CE1-CG1 4.41Å; F383-I390 HydrophobicContact CE1-CG2 3.87Å; F383-I390 HydrophobicContact CE2-CB 4.01Å; F383-I390 HydrophobicContact CE2-CG1 3.68Å; F383-I390 HydrophobicContact CG-CB 4.43Å; F383-I390 HydrophobicContact CZ-CB 3.73Å; F383-I390 HydrophobicContact CZ-CG1 3.82Å; F383-I390 HydrophobicContact CZ-CG2 3.8Å; F383-I390 PolarHBondContact N-O 3.41Å; F383-I390 VanDerWaalsContact N-O 3.16Å; F383-I390 PolarHBondContact O-N 2.67Å; L385-I390 HydrophobicContact CB-CD1 4.05Å; L385-I390 HydrophobicContact CB-CG1 3.72Å; L385-I390 HydrophobicContact CD2-CD1 4.43Å; L385-I390 HydrophobicContact CD2-CG1 4.32Å; I390-V396 HydrophobicContact CG2-CG2 3.73Å
391P97.4Very high96.5Very high1 Ų135.8 Ų35.81%0.00619%0.192CC..  trans-68.2148.7-173.5-17.630.5000112.5S35 L44 A379 Q389 G393 W394S35-P391 WeakPolarHBondContact O-CB 3.36Å; L44-P391 HydrophobicContact CD2-CG 3.43Å; L44-P391 VanDerWaalsContact CD2-CG 3.43Å; A379-P391 VanDerWaalsContact CB-O 3.31Å; A379-P391 WeakPolarHBondContact CB-O 3.39Å; Q389-P391 WeakPolarHBondContact O-CD 3.46Å; P391-G393 PolarHBondContact O-N 3.33Å; P391-W394 HydrophobicContact CB-CD2 4.5Å; P391-W394 HydrophobicContact CB-CG 4.16Å; P391-W394 HydrophobicContact CG-CD2 4.07Å; P391-W394 HydrophobicContact CG-CG 4.21Å; P391-W394 HydrophobicContact CG-CZ2 4.22Å; P391-W394 WeakPolarHBondContact O-CB 3.46Å; P391-W394 PolarHBondContact O-N 3.15Å
392K96.8Very high96.3Very high146 Ų14631.4 Ų31.464%0.63517%0.173SC*.THydrogen-bonded Turntrans-51.7137.8171.6-178.6174.5178.2-177.90111.2L380 T382 W394L380-K392 WeakPolarHBondContact O-CD 3.42Å; L380-K392 WeakPolarHBondContact O-CE 3.31Å; L380-K392 WeakPolarHBondContact O-CG 3.39Å; T382-K392 PolarHBondContact OG1-N 3.37Å; K392-W394 VanDerWaalsContact C-N 3.25Å; K392-W394 PolarHBondContact O-N 3.13Å
393G95.4Very high96.1Very high45 Ų4529.9 Ų29.946%0.46416%0.164SC..THydrogen-bonded Turntrans82-9.4177.400000114.9A379 P391A379-G393 PolarHBondContact O-N 3.02Å; P391-G393 PolarHBondContact O-N 3.33Å
394W96.2Very high95.8Very high5 Ų529.3 Ų29.32%0.01916%0.161CC..  trans-70.6144.1173.9-77.743.4000111.1S35 L44 M49 K80 P87 V89 V378 A379 P391 K392S35-W394 WeakPolarHBondContact OG-CZ2 3.2Å; S35-W394 PolarHBondContact OG-NE1 2.89Å; L44-W394 HydrophobicContact CD1-CH2 4.06Å; L44-W394 HydrophobicContact CD1-CZ2 4.32Å; L44-W394 HydrophobicContact CD2-CH2 3.97Å; L44-W394 HydrophobicContact CD2-CZ2 4.08Å; M49-W394 HydrophobicContact CE-CH2 3.45Å; M49-W394 VanDerWaalsContact CE-CH2 3.45Å; M49-W394 HydrophobicContact CE-CZ2 4.02Å; M49-W394 HydrophobicContact CE-CZ3 3.94Å; M49-W394 HydrophobicContact SD-CH2 4.5Å; K80-W394 HydrophobicContact CB-CZ3 3.87Å; K80-W394 HydrophobicContact CD-CH2 4.4Å; P87-W394 HydrophobicContact CB-CD2 3.51Å; P87-W394 HydrophobicContact CB-CE3 3.78Å; P87-W394 HydrophobicContact CB-CG 3.98Å; P87-W394 HydrophobicContact CB-CH2 4.18Å; P87-W394 HydrophobicContact CB-CZ2 3.9Å; P87-W394 HydrophobicContact CB-CZ3 4.12Å; V89-W394 HydrophobicContact CG2-CE3 3.66Å; V89-W394 HydrophobicContact CG2-CZ3 4.16Å; V378-W394 WeakPolarHBondContact CA-O 3.35Å; A379-W394 PolarHBondContact N-O 3.34Å; P391-W394 HydrophobicContact CB-CD2 4.5Å; P391-W394 HydrophobicContact CB-CG 4.16Å; P391-W394 HydrophobicContact CG-CD2 4.07Å; P391-W394 HydrophobicContact CG-CG 4.21Å; P391-W394 HydrophobicContact CG-CZ2 4.22Å; P391-W394 WeakPolarHBondContact O-CB 3.46Å; P391-W394 PolarHBondContact O-N 3.15Å; K392-W394 VanDerWaalsContact C-N 3.25Å; K392-W394 PolarHBondContact O-N 3.13Å
395N95.9Very high95.5Very high21 Ų2125.2 Ų25.211%0.11214%0.143CC..EExtended strand (participates in β ladder)trans-69.3143.6169-74.8-2.6000109.3R86 P87 T88 V89 R377R86-N395 WeakPolarHBondContact CB-ND2 3.41Å; R86-N395 WeakPolarHBondContact CD-OD1 3.26Å; P87-N395 PolarHBondContact O-N 3.35Å; T88-N395 CarbonylContact C-O 3.59Å; T88-N395 VanDerWaalsContact CA-O 3.31Å; T88-N395 WeakPolarHBondContact CA-O 3.19Å; T88-N395 HydrophobicContact CG2-CB 4.09Å; T88-N395 WeakPolarHBondContact OG1-CB 3.23Å; V89-N395 PolarHBondContact N-O 3.02Å; R377-N395 CarbonylContact O-C 3.59Å; R377-N395 WeakPolarHBondContact O-CA 3.45Å
396V97.4Very high95Very high1 Ų126 Ų261%0.00615%0.149CC..EExtended strand (participates in β ladder)trans-125122.5172.2-179.90000107.6V89 V91 I100 V108 R377 I390V89-V396 CarbonylContact O-C 3.49Å; V89-V396 WeakPolarHBondContact O-CA 3.12Å; V91-V396 HydrophobicContact CG2-CG1 3.74Å; I100-V396 HydrophobicContact CD1-CG1 3.89Å; I100-V396 HydrophobicContact CG1-CG1 4.2Å; I100-V396 HydrophobicContact CG2-CG1 4.37Å; V108-V396 HydrophobicContact CG1-CG2 4.48Å; R377-V396 WeakPolarHBondContact CA-O 3.45Å; R377-V396 HydrophobicContact CB-CB 4.04Å; R377-V396 WeakPolarHBondContact CB-O 3.35Å; R377-V396 PolarHBondContact N-O 2.65Å; R377-V396 PolarHBondContact O-N 3.02Å; I390-V396 HydrophobicContact CG2-CG2 3.73Å
397I95.9Very high94.7Very high9 Ų922.4 Ų22.45%0.04613%0.13CC..EExtended strand (participates in β ladder)trans-115.4101.8176.3-53.5177.5000108.1L83 T88 V89 R90 V91 G375 F376L83-I397 HydrophobicContact CD1-CD1 4.17Å; T88-I397 HydrophobicContact CG2-CB 4.49Å; T88-I397 HydrophobicContact CG2-CD1 3.59Å; T88-I397 HydrophobicContact CG2-CG1 3.69Å; V89-I397 PolarHBondContact O-N 3.08Å; R90-I397 WeakPolarHBondContact CA-O 2.98Å; V91-I397 PolarHBondContact N-O 2.79Å; G375-I397 WeakPolarHBondContact O-CA 3.14Å; F376-I397 HydrophobicContact CD1-CD1 3.8Å; F376-I397 HydrophobicContact CD1-CG1 3.76Å; F376-I397 HydrophobicContact CE1-CD1 3.61Å; F376-I397 HydrophobicContact CE1-CG1 4.07Å
398Y96.2Very high94.1Very high18 Ų1828 Ų287%0.07115%0.152CC..EExtended strand (participates in β ladder)trans-79.4146.8171.474.5-88.1000110.1V91 V97 I100 L101 G374 G375 R377 I400V91-Y398 CarbonylContact O-C 3.28Å; V91-Y398 VanDerWaalsContact O-CA 3.24Å; V91-Y398 WeakPolarHBondContact O-CA 3.32Å; V97-Y398 HydrophobicContact CG1-CD2 3.8Å; V97-Y398 HydrophobicContact CG1-CG 4.32Å; I100-Y398 HydrophobicContact CG2-CD1 4.12Å; I100-Y398 HydrophobicContact CG2-CG 4.48Å; L101-Y398 HydrophobicContact CD1-CE2 4.38Å; L101-Y398 HydrophobicContact CD2-CD1 4.22Å; L101-Y398 HydrophobicContact CD2-CD2 4.33Å; L101-Y398 HydrophobicContact CD2-CE1 3.73Å; L101-Y398 HydrophobicContact CD2-CE2 3.85Å; L101-Y398 HydrophobicContact CD2-CG 4.5Å; L101-Y398 HydrophobicContact CG-CE2 4.46Å; G374-Y398 VanDerWaalsContact CA-O 3.22Å; G374-Y398 WeakPolarHBondContact CA-O 3.38Å; G375-Y398 VanDerWaalsContact CA-CE1 3.42Å; G375-Y398 PolarHBondContact N-O 3.3Å; G375-Y398 VanDerWaalsContact N-O 3.15Å; G375-Y398 VanDerWaalsContact O-CD1 3.28Å; G375-Y398 WeakPolarHBondContact O-CD1 3.45Å; G375-Y398 WeakPolarHBondContact O-CE1 3.49Å; G375-Y398 PolarHBondContact O-N 2.83Å; R377-Y398 HydrophobicContact CG-CD1 4.32Å; R377-Y398 HydrophobicContact CG-CE1 4.43Å; Y398-I400 HydrophobicContact CD2-CG1 4.31Å; Y398-I400 HydrophobicContact CE2-CD1 4.11Å; Y398-I400 HydrophobicContact CE2-CG1 3.84Å
399S95.1Very high93.3Very high0 Ų027.9 Ų27.90%016%0.156CC..EExtended strand (participates in β ladder)trans-116.4118.6-177.8-170.60000110.5V91 P373 C401 D402 T403V91-S399 PolarHBondContact O-N 3.18Å; P373-S399 CarbonylContact O-C 3.44Å; S399-C401 PolarHBondContact OG-SG 3.28Å; S399-C401 VanDerWaalsContact OG-SG 3.41Å; S399-D402 VanDerWaalsContact CB-OD2 3.29Å; S399-D402 WeakPolarHBondContact CB-OD2 3.46Å; S399-D402 VanDerWaalsContact OG-CB 3.31Å; S399-D402 WeakPolarHBondContact OG-CB 3.44Å; S399-D402 VanDerWaalsContact OG-CG 3.23Å; S399-D402 PolarHBondContact OG-N 3.46Å; S399-D402 PolarHBondContact OG-OD2 2.77Å; S399-T403 VanDerWaalsContact O-CB 3.22Å; S399-T403 WeakPolarHBondContact O-CB 3.07Å; S399-T403 PolarHBondContact O-N 3.07Å; S399-T403 PolarHBondContact O-OG1 2.94Å
400I95Very high92.6Very high4 Ų428.3 Ų28.32%0.02116%0.158CC..Hα-helixtrans-73.9-49.8173-69.1169.9000109P370 P373 Y398 D402 T403 H404 I435P370-I400 HydrophobicContact CB-CG2 3.99Å; P370-I400 HydrophobicContact CG-CG2 4.23Å; P373-I400 PolarHBondContact O-N 3.13Å; Y398-I400 HydrophobicContact CD2-CG1 4.31Å; Y398-I400 HydrophobicContact CE2-CD1 4.11Å; Y398-I400 HydrophobicContact CE2-CG1 3.84Å; I400-D402 PolarHBondContact O-N 2.79Å; I400-T403 PolarHBondContact O-N 3.15Å; I400-T403 VanDerWaalsContact O-N 3.11Å; I400-H404 WeakPolarHBondContact CG2-CE1 3.03Å; I400-H404 PolarHBondContact O-CD2 3.37Å; I400-H404 PolarHBondContact O-N 3.01Å; I400-I435 HydrophobicContact CG1-CD1 4.19Å; I400-I435 HydrophobicContact CG1-CG1 4.38Å; I400-I435 HydrophobicContact CG2-CG1 4.39Å
401C92.1Very high91.9Very high41 Ų4133.2 Ų33.228%0.27719%0.188SC..Hα-helixtrans-62.2-44.5-177.558.50000112.1P370 P373 S399 T403 H404 D405P370-C401 HydrophobicContact CG-CB 3.83Å; P373-C401 PolarHBondContact O-N 2.69Å; S399-C401 PolarHBondContact OG-SG 3.28Å; S399-C401 VanDerWaalsContact OG-SG 3.41Å; C401-T403 VanDerWaalsContact C-N 3.3Å; C401-T403 PolarHBondContact O-N 3.1Å; C401-H404 PolarHBondContact O-N 3.15Å; C401-D405 VanDerWaalsContact O-CB 3.31Å; C401-D405 WeakPolarHBondContact O-CB 3.42Å; C401-D405 PolarHBondContact O-N 3.11Å
402D92.8Very high91.3Very high11 Ų1136.7 Ų36.76%0.05921%0.212CC..Hα-helixtrans-68.6-31.9176.2-63.9-58.3000111.7R72 M92 S399 I400 D405 V406R72-D402 IonicContact CZ-OD1 2.77Å; R72-D402 IonicContact NH1-OD1 2.8Å; R72-D402 PolarHBondContact NH1-OD1 2.99Å; M92-D402 HydrophobicContact CB-CB 3.86Å; M92-D402 HydrophobicContact CE-CB 4.21Å; M92-D402 HydrophobicContact CG-CB 4.32Å; M92-D402 HydrophobicContact SD-CB 3.67Å; S399-D402 VanDerWaalsContact CB-OD2 3.29Å; S399-D402 WeakPolarHBondContact CB-OD2 3.46Å; S399-D402 VanDerWaalsContact OG-CB 3.31Å; S399-D402 WeakPolarHBondContact OG-CB 3.44Å; S399-D402 VanDerWaalsContact OG-CG 3.23Å; S399-D402 PolarHBondContact OG-N 3.46Å; S399-D402 PolarHBondContact OG-OD2 2.77Å; I400-D402 PolarHBondContact O-N 2.79Å; D402-D405 PolarHBondContact O-N 2.71Å; D402-V406 WeakPolarHBondContact O-CG1 3.48Å; D402-V406 VanDerWaalsContact O-CG2 3.25Å; D402-V406 WeakPolarHBondContact O-CG2 3.32Å; D402-V406 PolarHBondContact O-N 3.02Å
403T94Very high90.7Very high1 Ų132 Ų321%0.00619%0.192CC..Hα-helixtrans-67.3-42.8177.1-64.50000111.5G93 V97 S399 I400 C401 D405 V406 A407 I435G93-T403 PolarHBondContact N-OG1 3.34Å; V97-T403 VanDerWaalsContact CG2-OG1 3.29Å; V97-T403 WeakPolarHBondContact CG2-OG1 3.45Å; S399-T403 VanDerWaalsContact O-CB 3.22Å; S399-T403 WeakPolarHBondContact O-CB 3.07Å; S399-T403 PolarHBondContact O-N 3.07Å; S399-T403 PolarHBondContact O-OG1 2.94Å; I400-T403 PolarHBondContact O-N 3.15Å; I400-T403 VanDerWaalsContact O-N 3.11Å; C401-T403 VanDerWaalsContact C-N 3.3Å; C401-T403 PolarHBondContact O-N 3.1Å; T403-D405 VanDerWaalsContact C-N 3.32Å; T403-V406 PolarHBondContact O-N 3.41Å; T403-A407 WeakPolarHBondContact O-CB 3.25Å; T403-A407 PolarHBondContact O-N 2.92Å; T403-A407 VanDerWaalsContact O-N 3.15Å; T403-I435 HydrophobicContact CG2-CD1 4.45Å
404H92.7Very high90.4Very high1 Ų137.2 Ų37.21%0.00520%0.204CC..Hα-helixtrans-62.4-41.1172.5-63.1175000111.4R367 I400 C401 F410 T433 I435R367-H404 HydrophobicContact CG-CB 4.04Å; R367-H404 PolarHBondContact O-ND1 3.36Å; I400-H404 WeakPolarHBondContact CG2-CE1 3.03Å; I400-H404 PolarHBondContact O-CD2 3.37Å; I400-H404 PolarHBondContact O-N 3.01Å; C401-H404 PolarHBondContact O-N 3.15Å; H404-F410 WeakPolarHBondContact O-CD2 3.4Å; H404-T433 PolarHBondContact CD2-O 3.23Å; H404-I435 PolarHBondContact NE2-N 3Å
405D89.5Confident90.2Very high34 Ų3442 Ų4218%0.18223%0.227CC..Hα-helixtrans-69.7-33-178.6-169.838.8000112.8R72 C401 D402 T403 K413R72-D405 IonicContact CZ-OD2 3.81Å; R72-D405 IonicContact NH1-OD2 3.6Å; R72-D405 PolarHBondContact NH1-OD2 2.96Å; R72-D405 IonicContact NH2-OD2 3.02Å; R72-D405 PolarHBondContact NH2-OD2 3.26Å; C401-D405 VanDerWaalsContact O-CB 3.31Å; C401-D405 WeakPolarHBondContact O-CB 3.42Å; C401-D405 PolarHBondContact O-N 3.11Å; D402-D405 PolarHBondContact O-N 2.71Å; T403-D405 VanDerWaalsContact C-N 3.32Å; D405-K413 WeakPolarHBondContact O-CD 3.46Å; D405-K413 WeakPolarHBondContact O-CE 3.26Å; D405-K413 PolarHBondContact O-NZ 3.07Å
406V88.8Confident90.3Very high24 Ų2441.3 Ų41.315%0.14522%0.223CC..Hα-helixtrans-91.8-6.1178.7-56.10000113.8F77 D402 T403 D408F77-V406 HydrophobicContact CD1-CB 4.37Å; F77-V406 HydrophobicContact CD1-CG1 4.33Å; F77-V406 HydrophobicContact CD1-CG2 4.08Å; F77-V406 HydrophobicContact CE1-CB 3.62Å; F77-V406 HydrophobicContact CE1-CG1 3.79Å; F77-V406 HydrophobicContact CE1-CG2 3.7Å; F77-V406 HydrophobicContact CZ-CB 4.4Å; D402-V406 WeakPolarHBondContact O-CG1 3.48Å; D402-V406 VanDerWaalsContact O-CG2 3.25Å; D402-V406 WeakPolarHBondContact O-CG2 3.32Å; D402-V406 PolarHBondContact O-N 3.02Å; T403-V406 PolarHBondContact O-N 3.41Å; V406-D408 PolarHBondContact O-N 3.33Å
407A88.9Confident90.1Very high9 Ų943.5 Ų43.57%0.07423%0.234CC..  trans-65.5131.5-17900000111.8T403 N409 F410 K413 T433T403-A407 WeakPolarHBondContact O-CB 3.25Å; T403-A407 PolarHBondContact O-N 2.92Å; T403-A407 VanDerWaalsContact O-N 3.15Å; A407-N409 VanDerWaalsContact C-N 3.31Å; A407-N409 WeakPolarHBondContact CB-OD1 3.49Å; A407-N409 PolarHBondContact O-N 3.25Å; A407-F410 HydrophobicContact CB-CD2 3.81Å; A407-F410 HydrophobicContact CB-CE2 3.99Å; A407-K413 WeakPolarHBondContact O-CE 3.45Å; A407-K413 PolarHBondContact O-NZ 3.37Å; A407-T433 HydrophobicContact CB-CG2 4.11Å
408D83.6Confident90.1Very high152 Ų15243.1 Ų43.181%0.81323%0.232SC*.THydrogen-bonded Turntrans-75.1-19.6-172.7-61.8-39.6000113.4V406 F410V406-D408 PolarHBondContact O-N 3.33Å; D408-F410 PolarHBondContact O-N 3.01Å
409N79.6Confident89.9Confident63 Ų6345.1 Ų45.134%0.33725%0.245SC..THydrogen-bonded Turntrans-75.5-6.3178.865.1-30.9000113.7A407 D428A407-N409 VanDerWaalsContact C-N 3.31Å; A407-N409 WeakPolarHBondContact CB-OD1 3.49Å; A407-N409 PolarHBondContact O-N 3.25Å; N409-D428 PolarHBondContact ND2-OD2 3.39Å
410F83.8Confident89.7Confident9 Ų947 Ų474%0.03925%0.252CS..  trans-104.7111175.8-57.8-51.4000110.9R367 H404 A407 D408 K413 F421 F434R367-F410 HydrophobicContact CG-CE2 4.17Å; R367-F410 HydrophobicContact CG-CZ 4.33Å; H404-F410 WeakPolarHBondContact O-CD2 3.4Å; A407-F410 HydrophobicContact CB-CD2 3.81Å; A407-F410 HydrophobicContact CB-CE2 3.99Å; D408-F410 PolarHBondContact O-N 3.01Å; F410-K413 HydrophobicContact CB-CG 4.17Å; F410-K413 WeakPolarHBondContact O-CE 3.41Å; F410-K413 WeakPolarHBondContact O-CG 3.46Å; F410-F421 HydrophobicContact CE1-CE1 4.02Å; F410-F421 AromaticContact CE1-CZ 3.85Å; F410-F421 HydrophobicContact CE1-CZ 3.85Å; F410-F421 HydrophobicContact CZ-CE1 4.3Å; F410-F421 HydrophobicContact CZ-CZ 4.12Å; F410-F434 HydrophobicContact CZ-CB 4.26Å; F410-F434 HydrophobicContact CZ-CD2 4.44Å
411T82.3Confident89.4Confident103 Ų10348.2 Ų48.263%0.63226%0.257SS*.SBendtrans-87.1152.4168.754.50000110.7K413 R420T411-K413 PolarHBondContact O-N 3.42Å; T411-R420 PolarHBondContact O-NH1 2.97Å; T411-R420 PolarHBondContact O-NH2 2.87Å
412S85.3Confident89.1Confident73 Ų7349.7 Ų49.751%0.5126%0.261SS..SBendtrans46.963-176.8-57.10000112E414 E415 R420S412-E414 VanDerWaalsContact C-N 3.26Å; S412-E414 PolarHBondContact O-N 3.09Å; S412-E415 WeakPolarHBondContact CB-OE2 3.34Å; S412-E415 WeakPolarHBondContact O-CB 3.36Å; S412-E415 PolarHBondContact O-N 2.75Å; S412-R420 PolarHBondContact O-NH2 3.27Å
413K84.9Confident87.8Confident47 Ų4754.9 Ų54.920%0.20430%0.296CS..THydrogen-bonded Turntrans-67.7-25.4-160.6-61.8-171.2-178.2-179.30114R367 L368 D405 A407 F410 T411R367-K413 VanDerWaalsContact CZ-O 3.29Å; R367-K413 PolarHBondContact NH1-O 2.97Å; R367-K413 PolarHBondContact NH2-O 3.13Å; L368-K413 VanDerWaalsContact CD2-O 3.27Å; L368-K413 WeakPolarHBondContact CD2-O 3.25Å; D405-K413 WeakPolarHBondContact O-CD 3.46Å; D405-K413 WeakPolarHBondContact O-CE 3.26Å; D405-K413 PolarHBondContact O-NZ 3.07Å; A407-K413 WeakPolarHBondContact O-CE 3.45Å; A407-K413 PolarHBondContact O-NZ 3.37Å; F410-K413 HydrophobicContact CB-CG 4.17Å; F410-K413 WeakPolarHBondContact O-CE 3.41Å; F410-K413 WeakPolarHBondContact O-CG 3.46Å; T411-K413 PolarHBondContact O-N 3.42Å
414E88.3Confident85.8Confident155 Ų15559 Ų5972%0.72432%0.324SS*.THydrogen-bonded Turntrans-84-17.7177.9-60.181.7178.900112.9S412S412-E414 VanDerWaalsContact C-N 3.26Å; S412-E414 PolarHBondContact O-N 3.09Å
415E92.9Very high83.7Confident106 Ų10666.3 Ų66.350%0.49536%0.358SS..SBendtrans-77.9133.5179.4-171.1-179.5-178.100110.7E364 R367 S412 N417E364-E415 VanDerWaalsContact OE1-O 3.09Å; R367-E415 PolarHBondContact NH2-O 2.74Å; S412-E415 WeakPolarHBondContact CB-OE2 3.34Å; S412-E415 WeakPolarHBondContact O-CB 3.36Å; S412-E415 PolarHBondContact O-N 2.75Å; E415-N417 PolarHBondContact O-N 2.9Å; E415-N417 VanDerWaalsContact O-N 3.14Å
416F96.4Very high81.5Confident6 Ų671 Ų713%0.02639%0.39CS..  trans-77.795.1171.6-177.6-102.4000109.4Y317 H321 V324 V361 E364 L368 P418Y317-F416 HydrophobicContact CD1-CB 3.96Å; Y317-F416 HydrophobicContact CD1-CD1 4.47Å; Y317-F416 AromaticContact CD1-CD2 3.52Å; Y317-F416 HydrophobicContact CD1-CD2 3.52Å; Y317-F416 HydrophobicContact CD1-CE2 4.14Å; Y317-F416 AromaticContact CD1-CG 3.74Å; Y317-F416 HydrophobicContact CD1-CG 3.74Å; Y317-F416 AromaticContact CD2-CD2 3.94Å; Y317-F416 HydrophobicContact CD2-CD2 3.94Å; Y317-F416 AromaticContact CD2-CE2 3.85Å; Y317-F416 HydrophobicContact CD2-CE2 3.85Å; Y317-F416 HydrophobicContact CE1-CB 4.31Å; Y317-F416 HydrophobicContact CE1-CD2 4.05Å; Y317-F416 HydrophobicContact CE1-CG 4.42Å; Y317-F416 HydrophobicContact CE2-CD2 4.42Å; Y317-F416 AromaticContact CG-CD2 3.49Å; Y317-F416 HydrophobicContact CG-CD2 3.49Å; Y317-F416 VanDerWaalsContact CG-CD2 3.49Å; Y317-F416 AromaticContact CG-CE2 3.6Å; Y317-F416 HydrophobicContact CG-CE2 3.6Å; Y317-F416 HydrophobicContact CG-CG 4.02Å; Y317-F416 HydrophobicContact CG-CZ 4.18Å; H321-F416 HydrophobicContact CB-CD1 4.26Å; H321-F416 AromaticContact CG-CD1 3.81Å; H321-F416 AromaticContact ND1-CD1 3.78Å; V324-F416 HydrophobicContact CB-CE1 4.42Å; V324-F416 HydrophobicContact CG1-CE1 4.08Å; V324-F416 HydrophobicContact CG2-CD1 4.34Å; V324-F416 HydrophobicContact CG2-CE1 4.16Å; V361-F416 HydrophobicContact CG1-CZ 4.05Å; E364-F416 HydrophobicContact CB-CD2 4.39Å; E364-F416 HydrophobicContact CB-CE2 3.99Å; E364-F416 HydrophobicContact CG-CD2 3.62Å; E364-F416 HydrophobicContact CG-CE2 3.74Å; E364-F416 HydrophobicContact CG-CG 4.3Å; L368-F416 HydrophobicContact CD1-CB 4.1Å; L368-F416 HydrophobicContact CD1-CD2 3.75Å; L368-F416 HydrophobicContact CD1-CG 4.44Å; F416-P418 HydrophobicContact CD1-CG 4.31Å; F416-P418 HydrophobicContact CE1-CG 3.73Å; F416-P418 HydrophobicContact CZ-CG 3.91Å
417N94.9Very high79.4Confident47 Ų4776.5 Ų76.525%0.25141%0.414SS..  trans-128.394.5-179179.1-1.2000110.5E364 E415 D419 R420E364-N417 PolarHBondContact OE1-N 3.09Å; E364-N417 VanDerWaalsContact OE1-N 3.08Å; E415-N417 PolarHBondContact O-N 2.9Å; E415-N417 VanDerWaalsContact O-N 3.14Å; N417-D419 PolarHBondContact O-N 3.48Å; N417-D419 VanDerWaalsContact OD1-CB 3.29Å; N417-D419 WeakPolarHBondContact OD1-CB 3.32Å; N417-D419 PolarHBondContact OD1-N 2.66Å; N417-R420 VanDerWaalsContact O-CG 3.22Å; N417-R420 WeakPolarHBondContact O-CG 3.42Å; N417-R420 PolarHBondContact O-NE 3.39Å; N417-R420 VanDerWaalsContact O-NE 3.08Å
418P95.4Very high77.7Confident1 Ų178.8 Ų78.81%0.00643%0.425CS..G310 helixtrans-62.7-27.1176.1-25.436.3000114.3V324 Y357 C360 V361 E364 F416 R420 F421V324-P418 HydrophobicContact CG1-CG 3.8Å; V324-P418 HydrophobicContact CG2-CG 4.19Å; Y357-P418 HydrophobicContact CE2-CB 4.15Å; C360-P418 HydrophobicContact CB-CB 4.26Å; C360-P418 WeakPolarHBondContact CB-O 3.41Å; V361-P418 HydrophobicContact CB-CG 4.42Å; V361-P418 HydrophobicContact CG2-CB 3.88Å; V361-P418 HydrophobicContact CG2-CG 3.84Å; E364-P418 HydrophobicContact CB-CG 4.41Å; F416-P418 HydrophobicContact CD1-CG 4.31Å; F416-P418 HydrophobicContact CE1-CG 3.73Å; F416-P418 HydrophobicContact CZ-CG 3.91Å; P418-R420 PolarHBondContact O-N 3.03Å; P418-F421 PolarHBondContact O-N 3.38Å
419D92.6Very high76Confident61 Ų6176.8 Ų76.833%0.32642%0.423SS..G310 helixtrans-61.1-22-174.8-60.7-1.8000111.6K327 Y357 N417 F421 I422K327-D419 IonicContact NZ-OD1 3.23Å; K327-D419 PolarHBondContact NZ-OD1 3.4Å; K327-D419 VanDerWaalsContact NZ-OD1 3.16Å; K327-D419 IonicContact NZ-OD2 2.58Å; K327-D419 PolarHBondContact NZ-OD2 2.87Å; Y357-D419 WeakPolarHBondContact CE2-OD1 3.47Å; Y357-D419 PolarHBondContact OH-OD1 3.08Å; N417-D419 PolarHBondContact O-N 3.48Å; N417-D419 VanDerWaalsContact OD1-CB 3.29Å; N417-D419 WeakPolarHBondContact OD1-CB 3.32Å; N417-D419 PolarHBondContact OD1-N 2.66Å; D419-F421 PolarHBondContact O-N 2.92Å; D419-F421 VanDerWaalsContact O-N 3.09Å; D419-I422 HydrophobicContact CB-CD1 3.87Å; D419-I422 VanDerWaalsContact O-CB 3.28Å; D419-I422 WeakPolarHBondContact O-CB 3.23Å; D419-I422 PolarHBondContact O-N 2.81Å
420R89.5Confident74.6Confident40 Ų4077 Ų7715%0.15143%0.43CS..G310 helixtrans-61.4-16.6174.279.6-179.465.4-104.115.1114.7E364 T411 S412 N417 P418E364-R420 IonicContact OE1-CZ 3.93Å; E364-R420 IonicContact OE1-NE 2.72Å; E364-R420 PolarHBondContact OE1-NE 2.77Å; E364-R420 IonicContact OE1-NH2 3.22Å; E364-R420 VanDerWaalsContact OE2-CD 3.29Å; E364-R420 WeakPolarHBondContact OE2-CD 3.26Å; E364-R420 IonicContact OE2-NE 3.24Å; E364-R420 PolarHBondContact OE2-NE 3.44Å; T411-R420 PolarHBondContact O-NH1 2.97Å; T411-R420 PolarHBondContact O-NH2 2.87Å; S412-R420 PolarHBondContact O-NH2 3.27Å; N417-R420 VanDerWaalsContact O-CG 3.22Å; N417-R420 WeakPolarHBondContact O-CG 3.42Å; N417-R420 PolarHBondContact O-NE 3.39Å; N417-R420 VanDerWaalsContact O-NE 3.08Å; P418-R420 PolarHBondContact O-N 3.03Å
421F89.1Confident73.7Confident28 Ų2882.9 Ų82.912%0.12345%0.452CS..G310 helixtrans-103.6-3.6177.7-69.6-70.9000113.7C360 K363 E364 R367 F410 P418 D419 F434C360-F421 HydrophobicContact CB-CB 3.84Å; C360-F421 PolarHBondContact SG-O 3.09Å; C360-F421 VanDerWaalsContact SG-O 3.4Å; K363-F421 HydrophobicContact CB-CD1 4.15Å; K363-F421 HydrophobicContact CB-CD2 3.68Å; K363-F421 HydrophobicContact CB-CE1 4.21Å; K363-F421 HydrophobicContact CB-CE2 3.75Å; K363-F421 HydrophobicContact CB-CG 3.88Å; K363-F421 HydrophobicContact CB-CZ 4.02Å; K363-F421 HydrophobicContact CD-CB 4.02Å; K363-F421 HydrophobicContact CD-CD1 3.76Å; K363-F421 HydrophobicContact CD-CE1 4.32Å; K363-F421 HydrophobicContact CD-CG 3.85Å; E364-F421 HydrophobicContact CB-CD2 4.2Å; E364-F421 HydrophobicContact CB-CE2 4.02Å; E364-F421 VanDerWaalsContact OE2-CE2 3.27Å; E364-F421 WeakPolarHBondContact OE2-CE2 3.39Å; R367-F421 HydrophobicContact CB-CZ 4.42Å; F410-F421 HydrophobicContact CE1-CE1 4.02Å; F410-F421 AromaticContact CE1-CZ 3.85Å; F410-F421 HydrophobicContact CE1-CZ 3.85Å; F410-F421 HydrophobicContact CZ-CE1 4.3Å; F410-F421 HydrophobicContact CZ-CZ 4.12Å; P418-F421 PolarHBondContact O-N 3.38Å; D419-F421 PolarHBondContact O-N 2.92Å; D419-F421 VanDerWaalsContact O-N 3.09Å; F421-F434 HydrophobicContact CE1-CD1 4.45Å; F421-F434 HydrophobicContact CE1-CD2 4.37Å; F421-F434 HydrophobicContact CE1-CG 4.33Å; F421-F434 HydrophobicContact CZ-CD2 4.07Å; F421-F434 AromaticContact CZ-CE2 3.99Å; F421-F434 HydrophobicContact CZ-CE2 3.99Å; F421-F434 HydrophobicContact CZ-CG 4.48Å; F421-F434 HydrophobicContact CZ-CZ 4.32Å
422I85.7Confident73.9Confident73 Ų7379 Ų7937%0.37443%0.426SS..SBendtrans-60.7141.6168.1-66.4176.1000107.1Y357 D419 S424Y357-I422 HydrophobicContact CD2-CD1 4Å; Y357-I422 HydrophobicContact CD2-CG1 4.26Å; Y357-I422 HydrophobicContact CE2-CD1 4Å; D419-I422 HydrophobicContact CB-CD1 3.87Å; D419-I422 VanDerWaalsContact O-CB 3.28Å; D419-I422 WeakPolarHBondContact O-CB 3.23Å; D419-I422 PolarHBondContact O-N 2.81Å; I422-S424 PolarHBondContact O-N 3.46Å; I422-S424 PolarHBondContact O-OG 3.24Å
423P65.4Low74Confident120 Ų12076.2 Ų76.278%0.77941%0.406SS*.SBendtrans-59.994.7-160.121.7-34.2000113.3
424S52Low74.4Confident87 Ų8776 Ų7661%0.60841%0.405SS*.SBendtrans-118.630.6165.155.90000111I422I422-S424 PolarHBondContact O-N 3.46Å; I422-S424 PolarHBondContact O-OG 3.24Å
425H48.8Very low74.6Confident154 Ų15469.1 Ų69.171%0.71337%0.374SS*.  trans155.9130.5147.6-76.6-52.7000111.3E427H425-E427 VanDerWaalsContact C-N 3.27Å; H425-E427 PolarHBondContact O-N 2.83Å; H425-E427 VanDerWaalsContact O-N 3.11Å
426P43Very low74.7Confident133 Ų13364.9 Ų64.986%0.86436%0.355SS*.SBendtrans-70.95.6-176.1-18.131.5000117.8
427E45.8Very low74.7Confident139 Ų13966.6 Ų66.665%0.6536%0.363SS*.  trans-126.139.4-163.1-65.2-157.1161.500117.1H425 S430H425-E427 VanDerWaalsContact C-N 3.27Å; H425-E427 PolarHBondContact O-N 2.83Å; H425-E427 VanDerWaalsContact O-N 3.11Å; E427-S430 PolarHBondContact O-OG 3.19Å; E427-S430 VanDerWaalsContact O-OG 3.04Å
428D51.3Low74.6Confident57 Ų5765.3 Ų65.331%0.30536%0.361SS..THydrogen-bonded Turntrans-88.9-3.6-176.9-104.8-0.1000115.8N409 S430 R431N409-D428 PolarHBondContact ND2-OD2 3.39Å; D428-S430 VanDerWaalsContact C-N 3.26Å; D428-S430 PolarHBondContact O-N 2.77Å; D428-R431 PolarHBondContact O-N 3.1Å; D428-R431 IonicContact OD1-CZ 3.7Å; D428-R431 IonicContact OD1-NE 3.96Å
429S49.5Very low74.5Confident110 Ų11065.7 Ų65.777%0.76937%0.365SS*.THydrogen-bonded Turntrans-70.8-23.9174.1660000112.8R431S429-R431 VanDerWaalsContact C-N 3.3Å; S429-R431 PolarHBondContact O-N 3.48Å
430S50.4Low74.5Confident69 Ų6963.9 Ų63.948%0.48336%0.36SS..THydrogen-bonded Turntrans-70.4-27.3178.465.80000112.4E427 D428E427-S430 PolarHBondContact O-OG 3.19Å; E427-S430 VanDerWaalsContact O-OG 3.04Å; D428-S430 VanDerWaalsContact C-N 3.26Å; D428-S430 PolarHBondContact O-N 2.77Å
431R64.7Low74.7Confident131 Ų13164.1 Ų64.149%0.49437%0.367SS..THydrogen-bonded Turntrans-92.9-6.7-170.7-55.7-172.2-158-177.97.5114.9A94 D428 S429 T433A94-R431 WeakPolarHBondContact CB-O 3.29Å; D428-R431 PolarHBondContact O-N 3.1Å; D428-R431 IonicContact OD1-CZ 3.7Å; D428-R431 IonicContact OD1-NE 3.96Å; S429-R431 VanDerWaalsContact C-N 3.3Å; S429-R431 PolarHBondContact O-N 3.48Å; R431-T433 HydrophobicContact CB-CG2 3.99Å; R431-T433 PolarHBondContact O-N 2.84Å
432F85.8Confident74.9Confident21 Ų2164.5 Ų64.59%0.09237%0.368CS..  trans51.617.2-179.6-84.6-109000114.8R98 L101 L102 I435R98-F432 HydrophobicContact CB-CB 3.92Å; R98-F432 HydrophobicContact CB-CD1 3.81Å; R98-F432 HydrophobicContact CB-CD2 3.76Å; R98-F432 HydrophobicContact CB-CE1 4.24Å; R98-F432 HydrophobicContact CB-CE2 4.19Å; R98-F432 HydrophobicContact CB-CG 3.55Å; R98-F432 HydrophobicContact CB-CZ 4.41Å; R98-F432 HydrophobicContact CG-CD1 4.27Å; R98-F432 HydrophobicContact CG-CD2 3.51Å; R98-F432 HydrophobicContact CG-CE1 4.34Å; R98-F432 HydrophobicContact CG-CE2 3.59Å; R98-F432 HydrophobicContact CG-CG 3.88Å; R98-F432 HydrophobicContact CG-CZ 4.01Å; L101-F432 HydrophobicContact CB-CE1 4.05Å; L101-F432 HydrophobicContact CD1-CD1 4.16Å; L101-F432 HydrophobicContact CD1-CE1 3.84Å; L102-F432 HydrophobicContact CD1-CE2 4.44Å; L102-F432 HydrophobicContact CD1-CZ 4.39Å; L102-F432 HydrophobicContact CD2-CZ 4.03Å; L102-F432 HydrophobicContact CG-CZ 4.03Å; F432-I435 HydrophobicContact CB-CG2 4.19Å; F432-I435 HydrophobicContact CD1-CG2 3.79Å; F432-I435 HydrophobicContact CG-CG2 4.14Å
433T88.4Confident75.2Confident15 Ų1563.2 Ų63.29%0.09237%0.365CS..SBendtrans-76-26.8178.347.50000111.7A94 H404 A407 R431A94-T433 HydrophobicContact CB-CG2 4Å; H404-T433 PolarHBondContact CD2-O 3.23Å; A407-T433 HydrophobicContact CB-CG2 4.11Å; R431-T433 HydrophobicContact CB-CG2 3.99Å; R431-T433 PolarHBondContact O-N 2.84Å
434F91.7Very high76.7Confident43 Ų4360.2 Ų60.219%0.18935%0.347CS..  trans-129.3105.1174.9-176.5-109.8000110.8K363 L366 R367 F410 F421 P436K363-F434 HydrophobicContact CB-CE1 4.23Å; K363-F434 HydrophobicContact CB-CZ 3.86Å; K363-F434 HydrophobicContact CG-CE1 3.97Å; K363-F434 HydrophobicContact CG-CZ 4.06Å; K363-F434 WeakPolarHBondContact O-CE2 3.41Å; K363-F434 WeakPolarHBondContact O-CZ 3.28Å; L366-F434 HydrophobicContact CB-CZ 4.45Å; R367-F434 HydrophobicContact CB-CD2 4.24Å; R367-F434 HydrophobicContact CB-CE2 3.8Å; R367-F434 HydrophobicContact CG-CD2 4.34Å; R367-F434 HydrophobicContact CG-CE2 4.39Å; F410-F434 HydrophobicContact CZ-CB 4.26Å; F410-F434 HydrophobicContact CZ-CD2 4.44Å; F421-F434 HydrophobicContact CE1-CD1 4.45Å; F421-F434 HydrophobicContact CE1-CD2 4.37Å; F421-F434 HydrophobicContact CE1-CG 4.33Å; F421-F434 HydrophobicContact CZ-CD2 4.07Å; F421-F434 AromaticContact CZ-CE2 3.99Å; F421-F434 HydrophobicContact CZ-CE2 3.99Å; F421-F434 HydrophobicContact CZ-CG 4.48Å; F421-F434 HydrophobicContact CZ-CZ 4.32Å; F434-P436 HydrophobicContact CD1-CG 4.24Å; F434-P436 HydrophobicContact CE1-CG 3.62Å; F434-P436 HydrophobicContact CE2-CG 3.94Å; F434-P436 HydrophobicContact CZ-CB 4.36Å; F434-P436 HydrophobicContact CZ-CG 3.47Å; F434-P436 VanDerWaalsContact CZ-CG 3.47Å
435I94.2Very high78.7Confident11 Ų1157.3 Ų57.36%0.05633%0.325CS..  trans-136.149.5-172.352.2165.6000112.6V97 L101 I400 T403 H404 F432 F437 G438V97-I435 HydrophobicContact CB-CD1 4.38Å; V97-I435 HydrophobicContact CG1-CD1 3.44Å; V97-I435 VanDerWaalsContact CG1-CD1 3.44Å; L101-I435 HydrophobicContact CD1-CD1 4.14Å; I400-I435 HydrophobicContact CG1-CD1 4.19Å; I400-I435 HydrophobicContact CG1-CG1 4.38Å; I400-I435 HydrophobicContact CG2-CG1 4.39Å; T403-I435 HydrophobicContact CG2-CD1 4.45Å; H404-I435 PolarHBondContact NE2-N 3Å; F432-I435 HydrophobicContact CB-CG2 4.19Å; F432-I435 HydrophobicContact CD1-CG2 3.79Å; F432-I435 HydrophobicContact CG-CG2 4.14Å; I435-F437 PolarHBondContact O-N 3.42Å; I435-G438 PolarHBondContact O-N 2.75Å
436P94.8Very high80.9Confident17 Ų1750.5 Ų50.511%0.1130%0.297CS..THydrogen-bonded Turntrans-62.1-20.6-177.629-38.4000113.5L366 F434L366-P436 HydrophobicContact CB-CB 3.76Å; L366-P436 HydrophobicContact CB-CG 4.26Å; L366-P436 HydrophobicContact CD1-CB 4.29Å; L366-P436 HydrophobicContact CD1-CG 4.38Å; F434-P436 HydrophobicContact CD1-CG 4.24Å; F434-P436 HydrophobicContact CE1-CG 3.62Å; F434-P436 HydrophobicContact CE2-CG 3.94Å; F434-P436 HydrophobicContact CZ-CB 4.36Å; F434-P436 HydrophobicContact CZ-CG 3.47Å; F434-P436 VanDerWaalsContact CZ-CG 3.47Å
437F95.2Very high83.4Confident41 Ų4148.1 Ų48.118%0.1827%0.273CS..THydrogen-bonded Turntrans-104.716.4177.2-61.9-76.6000112.9L366 I435 C444 K447 A450 K451L366-F437 HydrophobicContact CD1-CE2 3.83Å; L366-F437 HydrophobicContact CD1-CZ 3.75Å; I435-F437 PolarHBondContact O-N 3.42Å; F437-C444 HydrophobicContact CB-CB 3.96Å; F437-C444 HydrophobicContact CD1-CB 4.11Å; F437-C444 PolarHBondContact O-N 3.44Å; F437-C444 VanDerWaalsContact O-N 3.09Å; F437-K447 HydrophobicContact CB-CB 4.39Å; F437-K447 HydrophobicContact CB-CD 4.04Å; F437-K447 HydrophobicContact CB-CG 4.1Å; F437-K447 HydrophobicContact CD1-CB 4.08Å; F437-K447 HydrophobicContact CD1-CG 3.99Å; F437-K447 HydrophobicContact CD2-CD 4.03Å; F437-K447 HydrophobicContact CD2-CG 3.7Å; F437-K447 HydrophobicContact CE1-CG 4.34Å; F437-K447 HydrophobicContact CE2-CG 4.08Å; F437-K447 HydrophobicContact CG-CB 4.12Å; F437-K447 HydrophobicContact CG-CD 4.06Å; F437-K447 HydrophobicContact CG-CG 3.65Å; F437-K447 HydrophobicContact CZ-CG 4.38Å; F437-A450 HydrophobicContact CE1-CB 4.01Å; F437-A450 HydrophobicContact CZ-CB 4.43Å; F437-K451 HydrophobicContact CE2-CG 4.47Å; F437-K451 HydrophobicContact CZ-CG 4.37Å
438G93.9Very high85.7Confident20 Ų2045.4 Ų45.421%0.20626%0.26CS..  trans65.8-150.6-171.700000112.5I435I435-G438 PolarHBondContact O-N 2.75Å
439G92.4Very high87.9Confident9 Ų943.1 Ų43.19%0.09325%0.247CC..  trans-171.7175.6-176.200000112.8
440G92.6Very high90.2Very high23 Ų2338.3 Ų38.324%0.23722%0.215CC..G310 helixtrans65.4-157.4-178.300000113.8R442 S443G440-R442 PolarHBondContact O-N 3.4Å; G440-R442 VanDerWaalsContact O-N 3.07Å; G440-S443 WeakPolarHBondContact O-CB 3.48Å; G440-S443 PolarHBondContact O-N 2.65Å; G440-S443 PolarHBondContact O-OG 3.36Å
441P93.1Very high92.4Very high45 Ų4538.2 Ų38.229%0.29221%0.206SC..G310 helixtrans-56.6-27.6-177-28.137000114.1L101 E104 H133 K137L101-P441 WeakPolarHBondContact O-CD 3.31Å; E104-P441 HydrophobicContact CB-CB 4.34Å; E104-P441 HydrophobicContact CB-CG 4.12Å; E104-P441 HydrophobicContact CG-CB 4.46Å; H133-P441 PolarHBondContact CE1-O 3.36Å; K137-P441 PolarHBondContact NZ-O 3.27Å
442R93.6Very high94Very high37 Ų3732.5 Ų32.514%0.1419%0.185CC..G310 helixtrans-98.118.4-179.3-61.3-73.5-174.8166.73.5113.7E104 V110 L125 L128 H129 H133 G440E104-R442 HydrophobicContact CG-CG 3.71Å; E104-R442 IonicContact OE1-CZ 3.53Å; E104-R442 IonicContact OE1-NE 2.93Å; E104-R442 PolarHBondContact OE1-NE 3.38Å; E104-R442 IonicContact OE1-NH2 3.71Å; E104-R442 PolarHBondContact OE1-NH2 2.94Å; V110-R442 VanDerWaalsContact CG1-NH2 3.3Å; L125-R442 PolarHBondContact O-NH1 2.91Å; L128-R442 VanDerWaalsContact O-CZ 3.23Å; L128-R442 PolarHBondContact O-NH1 3.46Å; L128-R442 PolarHBondContact O-NH2 3.2Å; H129-R442 PolarHBondContact ND1-NH2 3.47Å; H133-R442 PolarHBondContact CD2-NH1 3.19Å; H133-R442 WeakPolarHBondContact NE2-CD 3.28Å; H133-R442 PolarHBondContact NE2-NH1 3.02Å; G440-R442 PolarHBondContact O-N 3.4Å; G440-R442 VanDerWaalsContact O-N 3.07Å
443S93.8Very high94.5Very high46 Ų4631.6 Ų31.632%0.32218%0.181SC..  trans-53.1143.4170.258.80000111.1K137 G440 V445K137-S443 PolarHBondContact NZ-O 3.09Å; K137-S443 PolarHBondContact NZ-OG 2.91Å; G440-S443 WeakPolarHBondContact O-CB 3.48Å; G440-S443 PolarHBondContact O-N 2.65Å; G440-S443 PolarHBondContact O-OG 3.36Å; S443-V445 PolarHBondContact O-N 2.84Å
444C95.3Very high95Very high57 Ų5731 Ų3139%0.38518%0.178SC..  trans-55.3129.2179.8-1770000111.3F437 K447F437-C444 HydrophobicContact CB-CB 3.96Å; F437-C444 HydrophobicContact CD1-CB 4.11Å; F437-C444 PolarHBondContact O-N 3.44Å; F437-C444 VanDerWaalsContact O-N 3.09Å; C444-K447 HydrophobicContact CB-CB 4.37Å
445V94.4Very high95.3Very high25 Ų2530.6 Ų30.615%0.15218%0.176CC..THydrogen-bonded Turntrans-73.5-38.3177.9-65.50000112.1L125 K137 I140 M141 F144 S443 K447L125-V445 HydrophobicContact CD2-CG1 3.8Å; K137-V445 HydrophobicContact CD-CG1 4.13Å; K137-V445 HydrophobicContact CG-CG1 3.79Å; I140-V445 HydrophobicContact CG2-CB 4.22Å; I140-V445 HydrophobicContact CG2-CG2 3.91Å; M141-V445 HydrophobicContact CG-CG1 4.25Å; M141-V445 VanDerWaalsContact SD-CA 3.55Å; M141-V445 HydrophobicContact SD-CB 3.68Å; M141-V445 HydrophobicContact SD-CG1 3.81Å; F144-V445 HydrophobicContact CE2-CG2 4.4Å; S443-V445 PolarHBondContact O-N 2.84Å; V445-K447 PolarHBondContact O-N 2.85Å
446G94.6Very high95.5Very high12 Ų1230.1 Ų30.112%0.12417%0.173CC..THydrogen-bonded Turntrans-84.220.2178.500000114.2E448 F449 A450G446-E448 PolarHBondContact O-N 2.98Å; G446-F449 PolarHBondContact O-N 3Å; G446-A450 WeakPolarHBondContact O-CB 3.39Å; G446-A450 PolarHBondContact O-N 3.45Å
447K95.4Very high95.7Very high83 Ų8329.3 Ų29.336%0.36117%0.168SC..Hα-helixtrans-58-48.7-174.9172.8-178.8171.9-168.50112.4F437 C444 V445 K451F437-K447 HydrophobicContact CB-CB 4.39Å; F437-K447 HydrophobicContact CB-CD 4.04Å; F437-K447 HydrophobicContact CB-CG 4.1Å; F437-K447 HydrophobicContact CD1-CB 4.08Å; F437-K447 HydrophobicContact CD1-CG 3.99Å; F437-K447 HydrophobicContact CD2-CD 4.03Å; F437-K447 HydrophobicContact CD2-CG 3.7Å; F437-K447 HydrophobicContact CE1-CG 4.34Å; F437-K447 HydrophobicContact CE2-CG 4.08Å; F437-K447 HydrophobicContact CG-CB 4.12Å; F437-K447 HydrophobicContact CG-CD 4.06Å; F437-K447 HydrophobicContact CG-CG 3.65Å; F437-K447 HydrophobicContact CZ-CG 4.38Å; C444-K447 HydrophobicContact CB-CB 4.37Å; V445-K447 PolarHBondContact O-N 2.85Å; K447-K451 WeakPolarHBondContact O-CG 3.43Å; K447-K451 PolarHBondContact O-N 2.7Å
448E95.4Very high95.8Very high82 Ų8227.3 Ų27.338%0.38316%0.159SC..Hα-helixtrans-74.5-36.5-177.1-59.8-51.1132.200111.1L149 G446 A450 K451 V452L149-E448 HydrophobicContact CD1-CB 3.84Å; G446-E448 PolarHBondContact O-N 2.98Å; E448-A450 PolarHBondContact O-N 3.33Å; E448-K451 VanDerWaalsContact CD-NZ 3.28Å; E448-K451 PolarHBondContact O-N 3.03Å; E448-K451 IonicContact OE1-NZ 2.97Å; E448-K451 PolarHBondContact OE1-NZ 2.75Å; E448-K451 VanDerWaalsContact OE2-CD 3.24Å; E448-K451 WeakPolarHBondContact OE2-CD 3.49Å; E448-K451 IonicContact OE2-NZ 3.05Å; E448-K451 PolarHBondContact OE2-NZ 3.12Å; E448-V452 WeakPolarHBondContact O-CG2 3.37Å; E448-V452 PolarHBondContact O-N 2.96Å
449F96.4Very high95.9Very high8 Ų826.4 Ų26.44%0.03515%0.149CC..Hα-helixtrans-54.8-51.9168.5174.5-105.4000112.7F144 L149 Y152 I156 I188 I192 G446 K451 V452 L453F144-F449 HydrophobicContact CD1-CB 3.7Å; F144-F449 HydrophobicContact CD1-CG 4.18Å; F144-F449 HydrophobicContact CE1-CB 4.1Å; F144-F449 HydrophobicContact CE1-CG 4.16Å; L149-F449 HydrophobicContact CD2-CB 3.79Å; L149-F449 HydrophobicContact CD2-CD2 4.02Å; L149-F449 HydrophobicContact CD2-CG 4.43Å; Y152-F449 AromaticContact CD2-CD2 3.99Å; Y152-F449 HydrophobicContact CD2-CD2 3.99Å; Y152-F449 HydrophobicContact CD2-CE2 4.17Å; I156-F449 HydrophobicContact CD1-CE2 4Å; I188-F449 HydrophobicContact CG2-CZ 4.29Å; I192-F449 HydrophobicContact CD1-CE2 3.86Å; I192-F449 HydrophobicContact CD1-CZ 4.13Å; I192-F449 HydrophobicContact CG2-CE2 3.83Å; I192-F449 HydrophobicContact CG2-CZ 4.3Å; G446-F449 PolarHBondContact O-N 3Å; F449-K451 VanDerWaalsContact C-N 3.29Å; F449-K451 PolarHBondContact O-N 3.08Å; F449-V452 PolarHBondContact O-N 3.27Å; F449-L453 HydrophobicContact CE1-CD1 3.78Å; F449-L453 HydrophobicContact CE2-CD1 4.5Å; F449-L453 HydrophobicContact CZ-CD1 3.66Å; F449-L453 WeakPolarHBondContact O-CB 3.34Å; F449-L453 PolarHBondContact O-N 2.9Å
450A97.4Very high96.1Very high10 Ų1026.5 Ų26.58%0.08315%0.148CC..Hα-helixtrans-60.7-37.7-179.800000112.2T307 F437 G446 E448 L454T307-A450 HydrophobicContact CG2-CB 4.43Å; F437-A450 HydrophobicContact CE1-CB 4.01Å; F437-A450 HydrophobicContact CZ-CB 4.43Å; G446-A450 WeakPolarHBondContact O-CB 3.39Å; G446-A450 PolarHBondContact O-N 3.45Å; E448-A450 PolarHBondContact O-N 3.33Å; A450-L454 VanDerWaalsContact O-CB 3.3Å; A450-L454 WeakPolarHBondContact O-CB 3.43Å; A450-L454 WeakPolarHBondContact O-CD1 3.41Å; A450-L454 WeakPolarHBondContact O-CG 3.46Å; A450-L454 PolarHBondContact O-N 3.07Å
451K97.4Very high96.2Very high67 Ų6725.5 Ų25.529%0.29114%0.137SC..Hα-helixtrans-65.3-45.6175.3-74.7165.5161.1-178.80112.3F437 K447 E448 F449 K455F437-K451 HydrophobicContact CE2-CG 4.47Å; F437-K451 HydrophobicContact CZ-CG 4.37Å; K447-K451 WeakPolarHBondContact O-CG 3.43Å; K447-K451 PolarHBondContact O-N 2.7Å; E448-K451 VanDerWaalsContact CD-NZ 3.28Å; E448-K451 PolarHBondContact O-N 3.03Å; E448-K451 IonicContact OE1-NZ 2.97Å; E448-K451 PolarHBondContact OE1-NZ 2.75Å; E448-K451 VanDerWaalsContact OE2-CD 3.24Å; E448-K451 WeakPolarHBondContact OE2-CD 3.49Å; E448-K451 IonicContact OE2-NZ 3.05Å; E448-K451 PolarHBondContact OE2-NZ 3.12Å; F449-K451 VanDerWaalsContact C-N 3.29Å; F449-K451 PolarHBondContact O-N 3.08Å; K451-K455 WeakPolarHBondContact O-CB 3.31Å; K451-K455 WeakPolarHBondContact O-CG 3.17Å; K451-K455 PolarHBondContact O-N 3.12Å
452V97.6Very high96.3Very high11 Ų1123.3 Ų23.37%0.06712%0.123CC..Hα-helixtrans-61.1-50.1177.7166.90000109.8L149 V153 I156 M349 L352 E448 F449 L454 K455 I456L149-V452 HydrophobicContact CD1-CG2 4.38Å; V153-V452 HydrophobicContact CG2-CG1 4.15Å; I156-V452 HydrophobicContact CD1-CG1 4.37Å; M349-V452 HydrophobicContact CE-CG2 3.87Å; M349-V452 HydrophobicContact SD-CG1 4.17Å; M349-V452 HydrophobicContact SD-CG2 3.75Å; L352-V452 HydrophobicContact CD1-CG1 4.02Å; E448-V452 WeakPolarHBondContact O-CG2 3.37Å; E448-V452 PolarHBondContact O-N 2.96Å; F449-V452 PolarHBondContact O-N 3.27Å; V452-L454 PolarHBondContact O-N 3.42Å; V452-K455 PolarHBondContact O-N 2.87Å; V452-I456 HydrophobicContact CG1-CD1 3.73Å; V452-I456 WeakPolarHBondContact O-CG1 3.48Å; V452-I456 PolarHBondContact O-N 2.78Å
453L98.1Very high96.2Very high1 Ų123.8 Ų23.81%0.00512%0.124CC..Hα-helixtrans-56.5-51.4177.7-177.2158.6000111.8I156 M185 I188 T307 F449 K455 I456 F457I156-L453 HydrophobicContact CD1-CB 4.15Å; I156-L453 HydrophobicContact CG2-CG 4.21Å; M185-L453 HydrophobicContact CE-CD2 4.02Å; M185-L453 HydrophobicContact SD-CD1 4.16Å; M185-L453 HydrophobicContact SD-CD2 3.72Å; I188-L453 HydrophobicContact CD1-CD1 4.49Å; I188-L453 HydrophobicContact CG2-CD1 3.79Å; T307-L453 HydrophobicContact CG2-CD1 4.49Å; F449-L453 HydrophobicContact CE1-CD1 3.78Å; F449-L453 HydrophobicContact CE2-CD1 4.5Å; F449-L453 HydrophobicContact CZ-CD1 3.66Å; F449-L453 WeakPolarHBondContact O-CB 3.34Å; F449-L453 PolarHBondContact O-N 2.9Å; L453-K455 VanDerWaalsContact C-N 3.28Å; L453-K455 PolarHBondContact O-N 3.46Å; L453-I456 PolarHBondContact O-N 2.8Å; L453-F457 VanDerWaalsContact O-CB 3.3Å; L453-F457 WeakPolarHBondContact O-CB 3.26Å; L453-F457 PolarHBondContact O-N 3.21Å
454L98.6Very high96.1Very high4 Ų425.2 Ų25.22%0.02113%0.126CC..Hα-helixtrans-65.7-31.9-179-68.1170000112.2A310 A311 L314 I362 A450 V452 T458A310-L454 HydrophobicContact CB-CD1 3.83Å; A310-L454 HydrophobicContact CB-CD2 3.81Å; A310-L454 HydrophobicContact CB-CG 4.49Å; A311-L454 HydrophobicContact CB-CD2 4.09Å; L314-L454 HydrophobicContact CD1-CB 4.13Å; L314-L454 HydrophobicContact CD1-CD2 3.78Å; L314-L454 HydrophobicContact CD1-CG 4.42Å; I362-L454 HydrophobicContact CD1-CB 3.93Å; I362-L454 HydrophobicContact CG1-CB 4.29Å; I362-L454 HydrophobicContact CG2-CB 4.29Å; I362-L454 HydrophobicContact CG2-CD1 4Å; A450-L454 VanDerWaalsContact O-CB 3.3Å; A450-L454 WeakPolarHBondContact O-CB 3.43Å; A450-L454 WeakPolarHBondContact O-CD1 3.41Å; A450-L454 WeakPolarHBondContact O-CG 3.46Å; A450-L454 PolarHBondContact O-N 3.07Å; V452-L454 PolarHBondContact O-N 3.42Å; L454-T458 WeakPolarHBondContact O-CB 3.31Å; L454-T458 PolarHBondContact O-N 3.14Å; L454-T458 PolarHBondContact O-OG1 3.17Å
455K97.9Very high96Very high34 Ų3422.5 Ų22.515%0.14811%0.107CC..Hα-helixtrans-66.3-51172.6-80.1-174.6169.3-168.60111.4L352 L355 T358 I362 K451 V452 L453 F457 T458 V459L352-K455 HydrophobicContact CD2-CB 3.93Å; L352-K455 PolarHBondContact O-NZ 3.4Å; L355-K455 PolarHBondContact O-NZ 3.13Å; T358-K455 HydrophobicContact CG2-CG 4.38Å; I362-K455 HydrophobicContact CD1-CB 4.21Å; I362-K455 HydrophobicContact CD1-CG 3.47Å; I362-K455 VanDerWaalsContact CD1-CG 3.47Å; K451-K455 WeakPolarHBondContact O-CB 3.31Å; K451-K455 WeakPolarHBondContact O-CG 3.17Å; K451-K455 PolarHBondContact O-N 3.12Å; V452-K455 PolarHBondContact O-N 2.87Å; L453-K455 VanDerWaalsContact C-N 3.28Å; L453-K455 PolarHBondContact O-N 3.46Å; K455-F457 VanDerWaalsContact C-N 3.31Å; K455-F457 PolarHBondContact O-N 3.29Å; K455-T458 PolarHBondContact O-N 3.27Å; K455-V459 WeakPolarHBondContact O-CB 3.23Å; K455-V459 VanDerWaalsContact O-CG2 3.26Å; K455-V459 WeakPolarHBondContact O-CG2 3.34Å; K455-V459 PolarHBondContact O-N 3.12Å
456I97.9Very high96Very high0 Ų023.7 Ų23.70%011%0.113CC..Hα-helixtrans-57.3-48.8177.8-65.6164.5000109.6V153 I156 A157 L347 L352 V452 L453 T458 V459 E460V153-I456 HydrophobicContact CB-CD1 4.18Å; V153-I456 HydrophobicContact CG1-CD1 3.85Å; V153-I456 HydrophobicContact CG1-CG1 4.49Å; V153-I456 HydrophobicContact CG2-CD1 4.21Å; I156-I456 HydrophobicContact CB-CD1 3.84Å; I156-I456 HydrophobicContact CB-CG2 4.3Å; I156-I456 HydrophobicContact CD1-CD1 3.89Å; I156-I456 HydrophobicContact CG1-CD1 4.45Å; I156-I456 HydrophobicContact CG2-CB 3.89Å; I156-I456 HydrophobicContact CG2-CD1 3.88Å; I156-I456 HydrophobicContact CG2-CG2 3.68Å; A157-I456 HydrophobicContact CB-CG2 4.03Å; L347-I456 HydrophobicContact CD1-CG2 4.16Å; L352-I456 HydrophobicContact CD1-CD1 4.03Å; L352-I456 HydrophobicContact CD1-CG1 3.78Å; L352-I456 HydrophobicContact CD2-CG1 3.88Å; L352-I456 HydrophobicContact CG-CG1 4.47Å; V452-I456 HydrophobicContact CG1-CD1 3.73Å; V452-I456 WeakPolarHBondContact O-CG1 3.48Å; V452-I456 PolarHBondContact O-N 2.78Å; L453-I456 PolarHBondContact O-N 2.8Å; I456-T458 VanDerWaalsContact C-N 3.32Å; I456-T458 PolarHBondContact O-N 3.39Å; I456-V459 PolarHBondContact O-N 3.44Å; I456-V459 VanDerWaalsContact O-N 3.14Å; I456-E460 HydrophobicContact CG2-CG 4.21Å; I456-E460 WeakPolarHBondContact O-CG 3.33Å; I456-E460 PolarHBondContact O-N 3.35Å
457F98.4Very high96.1Very high0 Ų024.4 Ų24.40%011%0.112CC..Hα-helixtrans-55.3-45.5176.6-177.1-104.5000113V160 W167 V181 L184 M185 A311 I315 L453 K455 L461V160-F457 HydrophobicContact CG1-CD2 3.89Å; V160-F457 HydrophobicContact CG2-CD2 4Å; W167-F457 HydrophobicContact CH2-CZ 4.43Å; V181-F457 HydrophobicContact CG2-CZ 4.34Å; L184-F457 HydrophobicContact CD2-CD2 4.12Å; L184-F457 HydrophobicContact CD2-CE2 3.75Å; M185-F457 HydrophobicContact CE-CD2 4.33Å; M185-F457 HydrophobicContact CE-CE2 4.43Å; A311-F457 HydrophobicContact CB-CD1 3.89Å; A311-F457 HydrophobicContact CB-CE1 3.56Å; A311-F457 HydrophobicContact CB-CZ 3.96Å; I315-F457 HydrophobicContact CD1-CE1 4.03Å; I315-F457 HydrophobicContact CD1-CZ 3.68Å; I315-F457 HydrophobicContact CG1-CE1 4.03Å; I315-F457 HydrophobicContact CG1-CZ 4.18Å; L453-F457 VanDerWaalsContact O-CB 3.3Å; L453-F457 WeakPolarHBondContact O-CB 3.26Å; L453-F457 PolarHBondContact O-N 3.21Å; K455-F457 VanDerWaalsContact C-N 3.31Å; K455-F457 PolarHBondContact O-N 3.29Å; F457-L461 HydrophobicContact CD1-CD1 3.69Å; F457-L461 HydrophobicContact CE1-CD1 3.26Å; F457-L461 HydrophobicContact CE1-CG 4.29Å; F457-L461 HydrophobicContact CE2-CD1 4.33Å; F457-L461 HydrophobicContact CG-CD1 4.41Å; F457-L461 HydrophobicContact CZ-CD1 3.65Å; F457-L461 HydrophobicContact CZ-CG 4.32Å; F457-L461 WeakPolarHBondContact O-CB 3.29Å; F457-L461 WeakPolarHBondContact O-CG 3.38Å; F457-L461 PolarHBondContact O-N 3.33Å
458T98.3Very high96.2Very high0 Ų026.1 Ų26.10%012%0.121CC..Hα-helixtrans-66.5-40.3178.2-55.80000111.9L318 V328 T358 L454 K455 I456 A462L318-T458 HydrophobicContact CD1-CG2 3.98Å; V328-T458 HydrophobicContact CG1-CG2 4.19Å; T358-T458 HydrophobicContact CG2-CG2 3.82Å; L454-T458 WeakPolarHBondContact O-CB 3.31Å; L454-T458 PolarHBondContact O-N 3.14Å; L454-T458 PolarHBondContact O-OG1 3.17Å; K455-T458 PolarHBondContact O-N 3.27Å; I456-T458 VanDerWaalsContact C-N 3.32Å; I456-T458 PolarHBondContact O-N 3.39Å; T458-A462 VanDerWaalsContact O-CB 3.27Å; T458-A462 WeakPolarHBondContact O-CB 3.45Å; T458-A462 PolarHBondContact O-N 3.16Å
459V96.3Very high96.3Very high0 Ų023 Ų230%011%0.107CC..Hα-helixtrans-63.7-50.7178.1170.10000110.5I332 L337 L347 L355 K455 I456 L461 A462 R463I332-V459 HydrophobicContact CD1-CB 4.26Å; I332-V459 HydrophobicContact CD1-CG1 4.25Å; I332-V459 HydrophobicContact CD1-CG2 4.02Å; I332-V459 HydrophobicContact CG1-CG2 4.29Å; I332-V459 HydrophobicContact CG2-CG1 4.49Å; L337-V459 HydrophobicContact CD1-CG1 4.26Å; L347-V459 HydrophobicContact CD1-CG1 4.1Å; L347-V459 HydrophobicContact CD2-CG1 4.16Å; L355-V459 HydrophobicContact CD1-CG2 3.31Å; K455-V459 WeakPolarHBondContact O-CB 3.23Å; K455-V459 VanDerWaalsContact O-CG2 3.26Å; K455-V459 WeakPolarHBondContact O-CG2 3.34Å; K455-V459 PolarHBondContact O-N 3.12Å; I456-V459 PolarHBondContact O-N 3.44Å; I456-V459 VanDerWaalsContact O-N 3.14Å; V459-L461 PolarHBondContact O-N 2.95Å; V459-A462 PolarHBondContact O-N 3.28Å; V459-R463 VanDerWaalsContact CG1-CD 3.43Å; V459-R463 HydrophobicContact CG1-CG 4.1Å; V459-R463 WeakPolarHBondContact O-CB 3.38Å; V459-R463 WeakPolarHBondContact O-CG 3.36Å; V459-R463 PolarHBondContact O-N 2.96Å
460E95.4Very high96.3Very high12 Ų1226.2 Ų26.26%0.05612%0.124CC..Hα-helixtrans-62.6-42.3-179.9-67.8-55.9126.100111.6V160 L164 L347 I456 A462 R463 H464V160-E460 HydrophobicContact CB-CB 4.47Å; V160-E460 HydrophobicContact CB-CG 4.45Å; V160-E460 HydrophobicContact CG1-CB 3.55Å; V160-E460 HydrophobicContact CG1-CG 4.04Å; L164-E460 HydrophobicContact CD1-CB 3.92Å; L347-E460 HydrophobicContact CD1-CG 4.49Å; L347-E460 VanDerWaalsContact CD1-OE1 3.24Å; L347-E460 WeakPolarHBondContact CD1-OE1 3.48Å; I456-E460 HydrophobicContact CG2-CG 4.21Å; I456-E460 WeakPolarHBondContact O-CG 3.33Å; I456-E460 PolarHBondContact O-N 3.35Å; E460-A462 PolarHBondContact O-N 3.05Å; E460-R463 PolarHBondContact O-N 3.32Å; E460-R463 IonicContact OE1-CZ 2.69Å; E460-R463 IonicContact OE1-NH1 3.16Å; E460-R463 PolarHBondContact OE1-NH1 2.84Å; E460-H464 WeakPolarHBondContact O-CB 3.35Å; E460-H464 PolarHBondContact O-CD2 3.02Å; E460-H464 VanDerWaalsContact O-CD2 3.26Å; E460-H464 PolarHBondContact O-N 3.31Å; E460-H464 IonicContact OE2-CD2 2.7Å; E460-H464 PolarHBondContact OE2-CD2 3.3Å; E460-H464 VanDerWaalsContact OE2-CD2 3.24Å; E460-H464 IonicContact OE2-NE2 2.83Å; E460-H464 PolarHBondContact OE2-NE2 3.28Å
461L95.9Very high96.2Very high1 Ų130.8 Ų30.81%0.00515%0.147CC..Hα-helixtrans-56.7-50.7171.3-83.4172.1000112.2L164 W167 I315 F457 V459 R463 H464 C465 W467 F492L164-L461 HydrophobicContact CD1-CD2 4.4Å; L164-L461 HydrophobicContact CD2-CD2 3.56Å; L164-L461 HydrophobicContact CD2-CG 4.32Å; W167-L461 HydrophobicContact CZ3-CD2 4.46Å; I315-L461 HydrophobicContact CD1-CD1 4.21Å; I315-L461 HydrophobicContact CG1-CD1 3.65Å; F457-L461 HydrophobicContact CD1-CD1 3.69Å; F457-L461 HydrophobicContact CE1-CD1 3.26Å; F457-L461 HydrophobicContact CE1-CG 4.29Å; F457-L461 HydrophobicContact CE2-CD1 4.33Å; F457-L461 HydrophobicContact CG-CD1 4.41Å; F457-L461 HydrophobicContact CZ-CD1 3.65Å; F457-L461 HydrophobicContact CZ-CG 4.32Å; F457-L461 WeakPolarHBondContact O-CB 3.29Å; F457-L461 WeakPolarHBondContact O-CG 3.38Å; F457-L461 PolarHBondContact O-N 3.33Å; V459-L461 PolarHBondContact O-N 2.95Å; L461-R463 VanDerWaalsContact C-N 3.29Å; L461-R463 PolarHBondContact O-N 2.77Å; L461-H464 PolarHBondContact O-N 2.95Å; L461-C465 WeakPolarHBondContact O-CB 3.46Å; L461-C465 PolarHBondContact O-N 3.27Å; L461-C465 VanDerWaalsContact O-O 3.13Å; L461-W467 HydrophobicContact CB-CH2 4.42Å; L461-W467 HydrophobicContact CB-CZ3 4.3Å; L461-W467 HydrophobicContact CD2-CZ3 4.47Å; L461-F492 HydrophobicContact CD2-CE1 4Å
462A95.3Very high96Very high0 Ų028.9 Ų28.90%015%0.147CC..Hα-helixtrans-66.6-31-177.200000112.8L325 V328 R329 I332 T458 V459 E460L325-A462 HydrophobicContact CD1-CB 3.99Å; V328-A462 HydrophobicContact CG1-CB 3.97Å; R329-A462 HydrophobicContact CG-CB 4.08Å; R329-A462 PolarHBondContact NE-O 3.04Å; I332-A462 HydrophobicContact CD1-CB 3.67Å; T458-A462 VanDerWaalsContact O-CB 3.27Å; T458-A462 WeakPolarHBondContact O-CB 3.45Å; T458-A462 PolarHBondContact O-N 3.16Å; V459-A462 PolarHBondContact O-N 3.28Å; E460-A462 PolarHBondContact O-N 3.05Å
463R90.6Very high95.9Very high47 Ų4733.2 Ų33.218%0.17718%0.175CC..Hα-helixtrans-74.6-40.1178.3-73.8172.779.7-164.67.4113.2I332 L337 L338 V459 E460 L461I332-R463 HydrophobicContact CG2-CG 3.96Å; L337-R463 PolarHBondContact O-NE 2.84Å; L337-R463 PolarHBondContact O-NH2 2.75Å; L338-R463 HydrophobicContact CD2-CB 4.2Å; L338-R463 HydrophobicContact CD2-CG 3.95Å; L338-R463 HydrophobicContact CG-CG 4.39Å; V459-R463 VanDerWaalsContact CG1-CD 3.43Å; V459-R463 HydrophobicContact CG1-CG 4.1Å; V459-R463 WeakPolarHBondContact O-CB 3.38Å; V459-R463 WeakPolarHBondContact O-CG 3.36Å; V459-R463 PolarHBondContact O-N 2.96Å; E460-R463 PolarHBondContact O-N 3.32Å; E460-R463 IonicContact OE1-CZ 2.69Å; E460-R463 IonicContact OE1-NH1 3.16Å; E460-R463 PolarHBondContact OE1-NH1 2.84Å; L461-R463 VanDerWaalsContact C-N 3.29Å; L461-R463 PolarHBondContact O-N 2.77Å
464H91.3Very high95.7Very high75 Ų7534.3 Ų34.335%0.34718%0.182SC..Hα-helixtrans-108.1-25.4-167.1-67.4-72.7000114.3E460 L461 H494 F495E460-H464 WeakPolarHBondContact O-CB 3.35Å; E460-H464 PolarHBondContact O-CD2 3.02Å; E460-H464 VanDerWaalsContact O-CD2 3.26Å; E460-H464 PolarHBondContact O-N 3.31Å; E460-H464 IonicContact OE2-CD2 2.7Å; E460-H464 PolarHBondContact OE2-CD2 3.3Å; E460-H464 VanDerWaalsContact OE2-CD2 3.24Å; E460-H464 IonicContact OE2-NE2 2.83Å; E460-H464 PolarHBondContact OE2-NE2 3.28Å; L461-H464 PolarHBondContact O-N 2.95Å; H464-H494 WeakPolarHBondContact O-CA 3.37Å; H464-F495 PolarHBondContact O-N 2.6Å
465C94.1Very high95.5Very high0 Ų038.7 Ų38.70%021%0.21CC..EExtended strand (participates in β ladder)trans-127.4137.9-165.8-570000113.3R329 L461 W467 F492 T493R329-C465 PolarHBondContact NH2-O 3.4Å; L461-C465 WeakPolarHBondContact O-CB 3.46Å; L461-C465 PolarHBondContact O-N 3.27Å; L461-C465 VanDerWaalsContact O-O 3.13Å; C465-W467 HydrophobicContact CB-CE3 4.18Å; C465-F492 HydrophobicContact CB-CD1 4.02Å; C465-T493 CarbonylContact C-O 3.57Å; C465-T493 WeakPolarHBondContact CA-O 3.43Å
466D94.8Very high95.2Very high51 Ų5139.4 Ų39.427%0.27321%0.214SC..EExtended strand (participates in β ladder)trans-97.3154.1145.6-70.3-53.7000108.6R329 F492 T493 F495R329-D466 IonicContact CZ-OD1 2.88Å; R329-D466 VanDerWaalsContact CZ-OD1 3.23Å; R329-D466 IonicContact NH1-OD1 2.81Å; R329-D466 PolarHBondContact NH1-OD1 3.32Å; R329-D466 IonicContact NH2-OD1 2.6Å; R329-D466 PolarHBondContact NH2-OD1 2.75Å; D466-F492 WeakPolarHBondContact O-CA 3.37Å; D466-T493 PolarHBondContact N-O 3.34Å; D466-T493 PolarHBondContact O-N 2.87Å; D466-F495 WeakPolarHBondContact OD2-CD2 3.41Å
467W96.2Very high94.9Very high26 Ų2643.5 Ų43.510%0.09823%0.232CC..EExtended strand (participates in β ladder)trans-150.8155.7173.865.297.5000113.2I315 L318 L325 L461 C465 R491 F492I315-W467 PolarHBondContact O-NE1 3.05Å; L318-W467 HydrophobicContact CB-CH2 4.02Å; L318-W467 HydrophobicContact CB-CZ2 3.57Å; L318-W467 HydrophobicContact CD1-CH2 4.42Å; L325-W467 HydrophobicContact CD1-CH2 3.99Å; L325-W467 HydrophobicContact CD1-CZ3 4.39Å; L325-W467 HydrophobicContact CD2-CH2 3.86Å; L325-W467 HydrophobicContact CD2-CZ3 3.93Å; L461-W467 HydrophobicContact CB-CH2 4.42Å; L461-W467 HydrophobicContact CB-CZ3 4.3Å; L461-W467 HydrophobicContact CD2-CZ3 4.47Å; C465-W467 HydrophobicContact CB-CE3 4.18Å; W467-R491 CarbonylContact C-O 3.54Å; W467-R491 WeakPolarHBondContact CA-O 3.44Å; W467-R491 VanDerWaalsContact CB-O 3.28Å; W467-R491 WeakPolarHBondContact CB-O 3.46Å; W467-F492 HydrophobicContact CB-CD1 3.72Å; W467-F492 HydrophobicContact CB-CD2 4.44Å; W467-F492 HydrophobicContact CB-CE1 3.83Å; W467-F492 HydrophobicContact CB-CG 4.04Å; W467-F492 HydrophobicContact CB-CZ 4.25Å; W467-F492 HydrophobicContact CD2-CE1 4.23Å; W467-F492 HydrophobicContact CE3-CE1 4.41Å; W467-F492 HydrophobicContact CG-CD1 4.34Å; W467-F492 AromaticContact CG-CE1 3.99Å; W467-F492 HydrophobicContact CG-CE1 3.99Å; W467-F492 HydrophobicContact CG-CZ 4.37Å
468Q96.1Very high94.3Very high120 Ų12046.4 Ų46.456%0.56125%0.25SC*.EExtended strand (participates in β ladder)trans-124.3130.2176.2-174.8-178.31200109.9A490 R491Q468-A490 VanDerWaalsContact O-CA 3.26Å; Q468-A490 WeakPolarHBondContact O-CA 3.46Å; Q468-R491 PolarHBondContact N-O 3.02Å; Q468-R491 PolarHBondContact O-N 3.43Å
469L97.4Very high93.5Very high17 Ų1749.5 Ų49.59%0.08927%0.271CS..EExtended strand (participates in β ladder)trans-76.3124.9170.2-54.9-175.1000109.3L320 N471 L488 A490L320-L469 HydrophobicContact CD1-CD1 4.38Å; L320-L469 HydrophobicContact CD2-CD1 3.9Å; L320-L469 HydrophobicContact CG-CD1 3.75Å; L469-N471 PolarHBondContact O-N 3.16Å; L469-L488 HydrophobicContact CD1-CD1 4.11Å; L469-L488 HydrophobicContact CD2-CD1 3.77Å; L469-L488 HydrophobicContact CD2-CD2 4.39Å; L469-L488 HydrophobicContact CD2-CG 4.04Å; L469-L488 HydrophobicContact CG-CD1 4.49Å; L469-A490 HydrophobicContact CD2-CB 4.08Å
470L96.4Very high92.6Very high75 Ų7552.7 Ų52.739%0.39329%0.292SS..THydrogen-bonded Turntrans-76.2-25.1-172.7-60.3178000113P489 R491L470-P489 HydrophobicContact CB-CB 4.28Å; L470-P489 HydrophobicContact CD1-CB 4.16Å; L470-P489 PolarHBondContact N-O 3.23Å; L470-R491 HydrophobicContact CD2-CB 4.2Å
471N95.8Very high92.4Very high105 Ų10552.5 Ų52.556%0.56129%0.291SS*.THydrogen-bonded Turntrans-109.67.9-177.7-64.4-20000113.6L469 D486L469-N471 PolarHBondContact O-N 3.16Å; N471-D486 PolarHBondContact ND2-OD2 3.3Å
472G93.5Very high92.3Very high27 Ų2752.8 Ų52.828%0.27829%0.293SS..SBendtrans71.1-150.6-173.100000113.3
473P94.8Very high92.2Very high103 Ų10355.3 Ų55.367%0.66930%0.303SS*.SBendtrans-62.2123.2-177.4-21.130.9000112.9L320L320-P473 HydrophobicContact CD1-CB 4.02Å; L320-P473 HydrophobicContact CD1-CG 4.38Å; L320-P473 HydrophobicContact CD2-CB 4.22Å; L320-P473 HydrophobicContact CD2-CG 3.79Å
474P94.9Very high92.5Very high23 Ų2353.1 Ų53.115%0.14930%0.295CS..  trans-74.1147.3-176.531.9-37.4000111.6A316 M476 P484 L488A316-P474 HydrophobicContact CB-CG 4.03Å; P474-M476 HydrophobicContact CB-SD 4.18Å; P474-M476 HydrophobicContact CG-SD 3.85Å; P474-M476 PolarHBondContact O-N 3.35Å; P474-P484 HydrophobicContact CB-CB 3.93Å; P474-L488 HydrophobicContact CB-CD1 3.93Å; P474-L488 HydrophobicContact CG-CD1 3.81Å
475T94.1Very high92.7Very high97 Ų9752.5 Ų52.560%0.59530%0.297SS*.  trans-77.3114.5163.8-64.50000109V485T475-V485 HydrophobicContact CG2-CG2 4.09Å; T475-V485 VanDerWaalsContact O-CG2 3.31Å; T475-V485 WeakPolarHBondContact O-CG2 3.42Å; T475-V485 PolarHBondContact O-N 3.34Å
476M92.2Very high92.8Very high49 Ų4954.9 Ų54.924%0.24131%0.309CS..EExtended strand (participates in β ladder)trans-87.6134.5176.1-54.9-60.1-74.400111.3P474 V482 Y483 P484P474-M476 HydrophobicContact CB-SD 4.18Å; P474-M476 HydrophobicContact CG-SD 3.85Å; P474-M476 PolarHBondContact O-N 3.35Å; M476-V482 HydrophobicContact CB-CG1 4.13Å; M476-V482 HydrophobicContact CE-CG1 3.68Å; M476-Y483 WeakPolarHBondContact CA-O 2.92Å; M476-P484 HydrophobicContact SD-CB 3.92Å
477K90.6Very high93Very high86 Ų8655.2 Ų55.237%0.37431%0.311SS..EExtended strand (participates in β ladder)trans-122.2165.2171.3-76.8-173.1-169.7157.90110.5V482 Y483 V485K477-V482 CarbonylContact O-C 3.58Å; K477-V482 VanDerWaalsContact O-CA 3.25Å; K477-V482 WeakPolarHBondContact O-CA 3.48Å; K477-Y483 HydrophobicContact CB-CD1 4.49Å; K477-Y483 HydrophobicContact CB-CE1 3.85Å; K477-Y483 PolarHBondContact N-O 3.31Å; K477-Y483 WeakPolarHBondContact O-CD1 3.08Å; K477-Y483 PolarHBondContact O-N 2.67Å; K477-V485 HydrophobicContact CB-CG2 4.1Å; K477-V485 HydrophobicContact CD-CG2 3.44Å; K477-V485 VanDerWaalsContact CD-CG2 3.44Å; K477-V485 VanDerWaalsContact CE-CG2 3.45Å; K477-V485 HydrophobicContact CG-CG2 3.49Å; K477-V485 VanDerWaalsContact CG-CG2 3.49Å
478T87.3Confident93Very high61 Ų6154 Ų5437%0.37431%0.307SS..EExtended strand (participates in β ladder)trans-120.6117.9176-46.10000110.1R64 P373 P480 T481 V482R64-T478 PolarHBondContact NH1-O 3.46Å; P373-T478 HydrophobicContact CB-CG2 4.24Å; P373-T478 HydrophobicContact CG-CG2 3.67Å; T478-P480 WeakPolarHBondContact CG2-O 3.48Å; T478-T481 CarbonylContact C-O 3.59Å; T478-T481 VanDerWaalsContact CA-O 3.28Å; T478-T481 WeakPolarHBondContact CA-O 3.27Å; T478-V482 HydrophobicContact CG2-CG2 4.25Å
479S80.5Confident93.1Very high64 Ų6449.3 Ų49.345%0.44829%0.286SS..SBendtrans-174.6100.3175.1-168.10000112.5T481S479-T481 VanDerWaalsContact C-N 3.31Å; S479-T481 PolarHBondContact N-O 3.28Å
480P78.6Confident93.2Very high67 Ų6748.5 Ų48.544%0.43528%0.282SS..SBendcis-73-23.6-23.132.8-33.5000112F224 T478F224-P480 HydrophobicContact CE2-CB 3.92Å; F224-P480 HydrophobicContact CE2-CG 4.39Å; T478-P480 WeakPolarHBondContact CG2-O 3.48Å
481T90.9Very high93.2Very high8 Ų849.1 Ų49.15%0.04928%0.279CS..SBendtrans-96.1171.7175.352.90000111.6E305 T306 P371 T478 S479 Y483E305-T481 HydrophobicContact CB-CG2 4.04Å; T306-T481 HydrophobicContact CG2-CG2 4.22Å; P371-T481 WeakPolarHBondContact O-CA 3.47Å; T478-T481 CarbonylContact C-O 3.59Å; T478-T481 VanDerWaalsContact CA-O 3.28Å; T478-T481 WeakPolarHBondContact CA-O 3.27Å; S479-T481 VanDerWaalsContact C-N 3.31Å; S479-T481 PolarHBondContact N-O 3.28Å; T481-Y483 WeakPolarHBondContact O-CD1 3.43Å
482V93.1Very high93.2Very high8 Ų844.2 Ų44.25%0.04825%0.253CS..EExtended strand (participates in β ladder)trans-78.5130.1178.2-1790000110.5S309 N369 P370 P371 M476 K477 T478S309-V482 WeakPolarHBondContact CB-O 3.47Å; S309-V482 PolarHBondContact OG-N 2.9Å; S309-V482 PolarHBondContact OG-O 3.07Å; N369-V482 HydrophobicContact CB-CG1 4.04Å; P370-V482 WeakPolarHBondContact O-CG2 3.5Å; P371-V482 PolarHBondContact O-N 2.82Å; M476-V482 HydrophobicContact CB-CG1 4.13Å; M476-V482 HydrophobicContact CE-CG1 3.68Å; K477-V482 CarbonylContact O-C 3.58Å; K477-V482 VanDerWaalsContact O-CA 3.25Å; K477-V482 WeakPolarHBondContact O-CA 3.48Å; T478-V482 HydrophobicContact CG2-CG2 4.25Å
483Y94.1Very high93.3Very high52 Ų5246.4 Ų46.420%0.20426%0.261CS..EExtended strand (participates in β ladder)trans-147.7151.6-178.769.4-78.8000112.1Y178 M476 K477 T481Y178-Y483 HydrophobicContact CE1-CD2 4.36Å; Y178-Y483 HydrophobicContact CE1-CG 4.22Å; M476-Y483 WeakPolarHBondContact CA-O 2.92Å; K477-Y483 HydrophobicContact CB-CD1 4.49Å; K477-Y483 HydrophobicContact CB-CE1 3.85Å; K477-Y483 PolarHBondContact N-O 3.31Å; K477-Y483 WeakPolarHBondContact O-CD1 3.08Å; K477-Y483 PolarHBondContact O-N 2.67Å; T481-Y483 WeakPolarHBondContact O-CD1 3.43Å
484P96.4Very high93.2Very high1 Ų147.7 Ų47.71%0.00626%0.258CS..EExtended strand (participates in β ladder)trans-74.5132.2172.130.8-33.9000110.6Y178 T312 P474 M476 D486 N487 L488Y178-P484 HydrophobicContact CG-CG 4.3Å; T312-P484 HydrophobicContact CG2-CG 3.75Å; P474-P484 HydrophobicContact CB-CB 3.93Å; M476-P484 HydrophobicContact SD-CB 3.92Å; P484-D486 VanDerWaalsContact C-N 3.27Å; P484-D486 PolarHBondContact O-N 2.85Å; P484-N487 PolarHBondContact O-N 2.82Å; P484-N487 VanDerWaalsContact O-N 3.17Å; P484-L488 HydrophobicContact CB-CB 3.97Å; P484-L488 HydrophobicContact CG-CB 3.69Å
485V95.4Very high93Very high63 Ų6347.8 Ų47.838%0.38226%0.256SS..THydrogen-bonded Turntrans-62.1-34.4-175.9173.20000113.3T475 K477 N487T475-V485 HydrophobicContact CG2-CG2 4.09Å; T475-V485 VanDerWaalsContact O-CG2 3.31Å; T475-V485 WeakPolarHBondContact O-CG2 3.42Å; T475-V485 PolarHBondContact O-N 3.34Å; K477-V485 HydrophobicContact CB-CG2 4.1Å; K477-V485 HydrophobicContact CD-CG2 3.44Å; K477-V485 VanDerWaalsContact CD-CG2 3.44Å; K477-V485 VanDerWaalsContact CE-CG2 3.45Å; K477-V485 HydrophobicContact CG-CG2 3.49Å; K477-V485 VanDerWaalsContact CG-CG2 3.49Å; V485-N487 VanDerWaalsContact C-N 3.32Å
486D96.5Very high92.5Very high49 Ų4952.9 Ų52.926%0.26226%0.264SS..THydrogen-bonded Turntrans-93.110.7-178.266-18.6000112.9N471 P484 L488 P489N471-D486 PolarHBondContact ND2-OD2 3.3Å; P484-D486 VanDerWaalsContact C-N 3.27Å; P484-D486 PolarHBondContact O-N 2.85Å; D486-L488 PolarHBondContact O-N 3.19Å; D486-L488 PolarHBondContact OD1-N 3.49Å; D486-L488 VanDerWaalsContact OD1-N 3.11Å; D486-P489 WeakPolarHBondContact O-CD 3.46Å; D486-P489 VanDerWaalsContact OD2-CD 3.25Å; D486-P489 WeakPolarHBondContact OD2-CD 3.35Å
487N97.3Very high91.6Very high58 Ų5852.6 Ų52.631%0.3127%0.273SS..  trans61.915.4-173.9-61.2-55.3000115L176 V177 Y178 P179 P484 V485L176-N487 HydrophobicContact CB-CB 4.07Å; L176-N487 HydrophobicContact CD1-CB 4.33Å; L176-N487 HydrophobicContact CD2-CB 4.33Å; L176-N487 HydrophobicContact CG-CB 4.48Å; V177-N487 PolarHBondContact N-O 3.38Å; V177-N487 VanDerWaalsContact N-O 3.14Å; Y178-N487 PolarHBondContact N-O 2.64Å; P179-N487 HydrophobicContact CG-CB 4.3Å; P484-N487 PolarHBondContact O-N 2.82Å; P484-N487 VanDerWaalsContact O-N 3.17Å; V485-N487 VanDerWaalsContact C-N 3.32Å
488L98Very high90.6Very high2 Ų255 Ų551%0.0129%0.291CS..  trans53.373.1178.5-169.372.9000113.4V177 T312 I315 A316 L469 P474 P484 D486 A490V177-L488 HydrophobicContact CB-CB 4.18Å; V177-L488 HydrophobicContact CB-CD2 4.06Å; V177-L488 HydrophobicContact CB-CG 4.29Å; V177-L488 WeakPolarHBondContact CB-O 3.47Å; V177-L488 HydrophobicContact CG1-CD2 4.03Å; V177-L488 HydrophobicContact CG2-CD2 4.44Å; V177-L488 VanDerWaalsContact CG2-O 3.25Å; V177-L488 WeakPolarHBondContact CG2-O 3.11Å; V177-L488 PolarHBondContact N-O 2.87Å; V177-L488 VanDerWaalsContact N-O 3.11Å; T312-L488 HydrophobicContact CG2-CB 4.37Å; T312-L488 HydrophobicContact CG2-CD2 3.74Å; I315-L488 HydrophobicContact CB-CD2 4.37Å; I315-L488 HydrophobicContact CG2-CD2 4.03Å; A316-L488 HydrophobicContact CB-CD1 4.06Å; A316-L488 HydrophobicContact CB-CD2 3.98Å; L469-L488 HydrophobicContact CD1-CD1 4.11Å; L469-L488 HydrophobicContact CD2-CD1 3.77Å; L469-L488 HydrophobicContact CD2-CD2 4.39Å; L469-L488 HydrophobicContact CD2-CG 4.04Å; L469-L488 HydrophobicContact CG-CD1 4.49Å; P474-L488 HydrophobicContact CB-CD1 3.93Å; P474-L488 HydrophobicContact CG-CD1 3.81Å; P484-L488 HydrophobicContact CB-CB 3.97Å; P484-L488 HydrophobicContact CG-CB 3.69Å; D486-L488 PolarHBondContact O-N 3.19Å; D486-L488 PolarHBondContact OD1-N 3.49Å; D486-L488 VanDerWaalsContact OD1-N 3.11Å; L488-A490 PolarHBondContact O-N 3.15Å
489P98Very high89.7Confident21 Ų2155.6 Ų55.614%0.13629%0.291CS..EExtended strand (participates in β ladder)trans-65125.6174.9-1934000110.6L175 L176 L470 D486L175-P489 WeakPolarHBondContact O-CA 3.33Å; L176-P489 HydrophobicContact CD2-CB 4.13Å; L176-P489 HydrophobicContact CD2-CG 3.79Å; L470-P489 HydrophobicContact CB-CB 4.28Å; L470-P489 HydrophobicContact CD1-CB 4.16Å; L470-P489 PolarHBondContact N-O 3.23Å; D486-P489 WeakPolarHBondContact O-CD 3.46Å; D486-P489 VanDerWaalsContact OD2-CD 3.25Å; D486-P489 WeakPolarHBondContact OD2-CD 3.35Å
490A97.9Very high90.1Very high0 Ų055.2 Ų55.20%028%0.283CS..EExtended strand (participates in β ladder)trans-142.8155.7-17900000112.1G174 L175 V177 Q468 L469 L488 F492G174-A490 CarbonylContact C-O 3.37Å; G174-A490 VanDerWaalsContact CA-O 3.22Å; G174-A490 WeakPolarHBondContact CA-O 3.39Å; L175-A490 PolarHBondContact N-O 3.19Å; L175-A490 PolarHBondContact O-N 2.98Å; V177-A490 HydrophobicContact CG2-CB 3.64Å; Q468-A490 VanDerWaalsContact O-CA 3.26Å; Q468-A490 WeakPolarHBondContact O-CA 3.46Å; L469-A490 HydrophobicContact CD2-CB 4.08Å; L488-A490 PolarHBondContact O-N 3.15Å; A490-F492 HydrophobicContact CB-CD2 4.49Å; A490-F492 HydrophobicContact CB-CE2 3.86Å
491R97.3Very high90.7Very high87 Ų8754.5 Ų54.533%0.32828%0.275SS..EExtended strand (participates in β ladder)trans-112.6130171.9-177.7-179.4-65.8159-4.8109.3E172 W467 Q468 L470E172-R491 PolarHBondContact O-NE 3.23Å; E172-R491 VanDerWaalsContact O-NE 3.1Å; E172-R491 PolarHBondContact O-NH2 3.42Å; W467-R491 CarbonylContact C-O 3.54Å; W467-R491 WeakPolarHBondContact CA-O 3.44Å; W467-R491 VanDerWaalsContact CB-O 3.28Å; W467-R491 WeakPolarHBondContact CB-O 3.46Å; Q468-R491 PolarHBondContact N-O 3.02Å; Q468-R491 PolarHBondContact O-N 3.43Å; L470-R491 HydrophobicContact CD2-CB 4.2Å
492F96.7Very high90.7Very high3 Ų357.1 Ų57.11%0.01329%0.287CS..EExtended strand (participates in β ladder)trans-107.8141.5178.7-69.3-102.2000110.4W167 L168 L175 V177 I315 L461 C465 D466 W467 A490W167-F492 HydrophobicContact CB-CD2 4.45Å; W167-F492 HydrophobicContact CB-CG 4.42Å; W167-F492 HydrophobicContact CE3-CD1 4.14Å; W167-F492 HydrophobicContact CE3-CD2 4.32Å; W167-F492 AromaticContact CE3-CE1 3.71Å; W167-F492 HydrophobicContact CE3-CE1 3.71Å; W167-F492 AromaticContact CE3-CE2 3.89Å; W167-F492 HydrophobicContact CE3-CE2 3.89Å; W167-F492 HydrophobicContact CE3-CG 4.44Å; W167-F492 AromaticContact CE3-CZ 3.57Å; W167-F492 HydrophobicContact CE3-CZ 3.57Å; W167-F492 AromaticContact CZ3-CE1 3.96Å; W167-F492 HydrophobicContact CZ3-CE1 3.96Å; W167-F492 HydrophobicContact CZ3-CE2 4.39Å; W167-F492 AromaticContact CZ3-CZ 3.73Å; W167-F492 HydrophobicContact CZ3-CZ 3.73Å; L168-F492 HydrophobicContact CD2-CB 4.26Å; L175-F492 HydrophobicContact CD1-CE2 4.49Å; L175-F492 HydrophobicContact CD2-CD2 3.68Å; L175-F492 HydrophobicContact CD2-CE2 4.01Å; L175-F492 HydrophobicContact CG-CD2 4.43Å; L175-F492 HydrophobicContact CG-CE2 4.34Å; V177-F492 HydrophobicContact CG2-CE2 3.75Å; V177-F492 HydrophobicContact CG2-CZ 4Å; I315-F492 HydrophobicContact CD1-CZ 4.45Å; I315-F492 HydrophobicContact CG2-CZ 4.3Å; L461-F492 HydrophobicContact CD2-CE1 4Å; C465-F492 HydrophobicContact CB-CD1 4.02Å; D466-F492 WeakPolarHBondContact O-CA 3.37Å; W467-F492 HydrophobicContact CB-CD1 3.72Å; W467-F492 HydrophobicContact CB-CD2 4.44Å; W467-F492 HydrophobicContact CB-CE1 3.83Å; W467-F492 HydrophobicContact CB-CG 4.04Å; W467-F492 HydrophobicContact CB-CZ 4.25Å; W467-F492 HydrophobicContact CD2-CE1 4.23Å; W467-F492 HydrophobicContact CE3-CE1 4.41Å; W467-F492 HydrophobicContact CG-CD1 4.34Å; W467-F492 AromaticContact CG-CE1 3.99Å; W467-F492 HydrophobicContact CG-CE1 3.99Å; W467-F492 HydrophobicContact CG-CZ 4.37Å; A490-F492 HydrophobicContact CB-CD2 4.49Å; A490-F492 HydrophobicContact CB-CE2 3.86Å
493T95.1Very high90.6Very high73 Ų7360 Ų6045%0.44830%0.301SS..EExtended strand (participates in β ladder)trans-137.6155.6175.7530000109.8C465 D466 F495C465-T493 CarbonylContact C-O 3.57Å; C465-T493 WeakPolarHBondContact CA-O 3.43Å; D466-T493 PolarHBondContact N-O 3.34Å; D466-T493 PolarHBondContact O-N 2.87Å; T493-F495 PolarHBondContact O-N 2.92Å
494H93.4Very high90.4Very high129 Ų12960.5 Ų60.560%0.59731%0.307SS*.EExtended strand (participates in β ladder)trans-62.6130.5177.3-75.1-84.2000111.3H464H464-H494 WeakPolarHBondContact O-CA 3.37Å
495F90.6Very high90Very high25 Ų2564.5 Ų64.511%0.1133%0.327CS..  trans-69.1129.3167.3176.8-124.8000109.6R329 L338 H464 D466 T493 G497 D498 I499R329-F495 VanDerWaalsContact NH1-CE2 3.33Å; L338-F495 HydrophobicContact CD2-CD1 4.28Å; L338-F495 HydrophobicContact CD2-CE1 4.02Å; H464-F495 PolarHBondContact O-N 2.6Å; D466-F495 WeakPolarHBondContact OD2-CD2 3.41Å; T493-F495 PolarHBondContact O-N 2.92Å; F495-G497 VanDerWaalsContact CE1-CA 3.44Å; F495-D498 WeakPolarHBondContact CE2-O 3.38Å; F495-I499 HydrophobicContact CE1-CG1 4.34Å; F495-I499 HydrophobicContact CZ-CG1 3.74Å
496R82.4Confident89.6Confident205 Ų20564.6 Ų64.677%0.77432%0.323SS*.  trans-86-5.6-172.9-66.2-173.3177.7-174.6-0.5114.7D498R496-D498 VanDerWaalsContact C-N 3.35Å
497G72.8Confident89Confident42 Ų4265.8 Ų65.843%0.43333%0.328SS..SBendtrans88.9-3.417800000114.9F495 I499F495-G497 VanDerWaalsContact CE1-CA 3.44Å; G497-I499 PolarHBondContact O-N 3.48Å
498D70.2Confident88.3Confident138 Ų13866.4 Ų66.474%0.73833%0.33SS*.  trans-84.5112.7175.4-58-38.7000108.6F495 R496F495-D498 WeakPolarHBondContact CE2-O 3.38Å; R496-D498 VanDerWaalsContact C-N 3.35Å
499I67.6Low87.5Confident72 Ų7272.3 Ų72.337%0.36936%0.359SS..  trans-107.10175.4-52.1170.5000108.9H326 R329 E330 K333 L338 F495 G497H326-I499 WeakPolarHBondContact CE1-CG2 3.42Å; H326-I499 PolarHBondContact CE1-OXT 2.88Å; H326-I499 VanDerWaalsContact ND1-CG2 3.31Å; H326-I499 WeakPolarHBondContact ND1-CG2 3.4Å; H326-I499 PolarHBondContact ND1-OXT 3.04Å; R329-I499 HydrophobicContact CB-CD1 3.84Å; R329-I499 HydrophobicContact CB-CG1 4.21Å; R329-I499 HydrophobicContact CB-CG2 4.49Å; E330-I499 HydrophobicContact CG-CG2 3.86Å; E330-I499 WeakPolarHBondContact OE1-CG2 3.45Å; K333-I499 HydrophobicContact CB-CD1 3.99Å; K333-I499 HydrophobicContact CD-CD1 3.53Å; K333-I499 HydrophobicContact CG-CD1 4.4Å; L338-I499 HydrophobicContact CD1-CD1 3.67Å; F495-I499 HydrophobicContact CE1-CG1 4.34Å; F495-I499 HydrophobicContact CZ-CG1 3.74Å; G497-I499 PolarHBondContact O-N 3.48Å

Retrieved 499 of 499 residues in 95.9 ms (Link to these results)