A0A061IBZ2_CRIGR Loading...

phosphorylase kinase

AlphaFold DB , UniProt , Accession A0A061IBZ2, Species CRIGR (Cricetulus griseus, Chinese hamster), Gene Phkg2, Length 406 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M34.3Very low36.3Very low245 Ų245153.5 Ų153.5100%1.20780%0.8SS**  01030-78.9175.9-176.100106.8
2T37.7Very low37.5Very low141 Ų141145.9 Ų145.987%0.86577%0.767SS**  trans-85.4113.9175.6370000108.8
3L31Very low39.2Very low160 Ų160139.5 Ų139.584%0.83873%0.733SS**  trans-160.9133.2169.6-71174.1000104.4
4D27.9Very low40.8Very low145 Ų145141.6 Ų141.678%0.77573%0.727SS**  cis-163.4126.97.6-147.9-8000104.2G6D4-G6 PolarHBondContact O-N 3.42Å
5V29.5Very low42.5Very low154 Ų154132.9 Ų132.993%0.93368%0.684SS**  trans-86.493.7178.3-179.60000106.6
6G30.6Very low44.4Very low56 Ų56124.6 Ų124.658%0.57764%0.642SS**  trans-74.2139.5-178.400000112.6D4 E8D4-G6 PolarHBondContact O-N 3.42Å; G6-E8 PolarHBondContact O-N 2.98Å
7R37.7Very low46.5Very low247 Ų247118.4 Ų118.493%0.93261%0.614SS**  trans-42.394.5169-75.7170.9161.4159-8.1112.5
8E40.5Very low48.6Very low173 Ų173117.7 Ų117.781%0.80861%0.605SS**  trans-131.4111.2161.3-73.1-173.5164.400105.8G6G6-E8 PolarHBondContact O-N 2.98Å
9D36.9Very low50.7Low167 Ų167115.8 Ų115.889%0.89359%0.593SS**  trans169.717.7157.1-84.4-17.5000112.9L11D9-L11 PolarHBondContact O-N 2.7Å
10E48.3Very low52.8Low146 Ų146110 Ų11068%0.68256%0.563SS**  trans-82.9103.8168.1-73.1-175.4-166.600109.9
11L44.4Very low54.7Low55 Ų55109.7 Ų109.729%0.28856%0.556SS.*  trans-60.6133.5171.6-74165.4000109.3D9 A15 A16 P100D9-L11 PolarHBondContact O-N 2.7Å; L11-A15 HydrophobicContact CB-CB 4.27Å; L11-A15 HydrophobicContact CD2-CB 4.13Å; L11-A16 HydrophobicContact CB-CB 4.02Å; L11-A16 HydrophobicContact CD1-CB 4.12Å; L11-P100 VanDerWaalsContact O-CD 3.27Å; L11-P100 WeakPolarHBondContact O-CD 3.35Å
12P51.2Low57.5Low62 Ų62103.9 Ų103.940%0.40353%0.526SS..  trans-50.3147.9169.3-24.529.5000111.2W14 A15 A16P12-W14 HydrophobicContact CB-CG 4.26Å; P12-W14 VanDerWaalsContact CB-NE1 3.28Å; P12-W14 HydrophobicContact CG-CZ2 4.5Å; P12-W14 PolarHBondContact O-N 2.97Å; P12-A15 HydrophobicContact CB-CB 4.04Å; P12-A15 HydrophobicContact CG-CB 4.08Å; P12-A15 WeakPolarHBondContact O-CA 3.15Å; P12-A15 WeakPolarHBondContact O-CB 3.11Å; P12-A15 PolarHBondContact O-N 3.01Å; P12-A16 PolarHBondContact O-N 2.77Å
13D59.6Low60.3Low62 Ų62100.6 Ų100.633%0.33250%0.499SS..Hα-helixtrans-50.3-37.8179.6-76.1-27.5000113.5A17 S99 P100 S101D13-A17 VanDerWaalsContact O-CB 3.3Å; D13-A17 WeakPolarHBondContact O-CB 3.34Å; D13-A17 PolarHBondContact O-N 3.25Å; D13-S99 WeakPolarHBondContact OD1-CB 3.34Å; D13-S99 PolarHBondContact OD1-OG 2.99Å; D13-P100 WeakPolarHBondContact OD1-CD 3.47Å; D13-S101 VanDerWaalsContact CG-OG 3.22Å; D13-S101 WeakPolarHBondContact OD1-CB 3.3Å; D13-S101 PolarHBondContact OD1-N 3.1Å; D13-S101 PolarHBondContact OD1-OG 2.73Å; D13-S101 WeakPolarHBondContact OD2-CB 3.32Å; D13-S101 PolarHBondContact OD2-OG 2.68Å
14W61.2Low63.4Low169 Ų16993.1 Ų93.164%0.6446%0.46SS*.Hα-helixtrans-72.8-28.1175.969-93.1000113.1P12 K18P12-W14 HydrophobicContact CB-CG 4.26Å; P12-W14 VanDerWaalsContact CB-NE1 3.28Å; P12-W14 HydrophobicContact CG-CZ2 4.5Å; P12-W14 PolarHBondContact O-N 2.97Å; W14-K18 HydrophobicContact CE3-CD 3.94Å; W14-K18 HydrophobicContact CZ3-CD 3.71Å; W14-K18 WeakPolarHBondContact O-CB 3.06Å; W14-K18 PolarHBondContact O-N 3.35Å
15A66.6Low66.6Low11 Ų1188.5 Ų88.59%0.09144%0.436CS..Hα-helixtrans-77.2-49-17600000111.6L11 P12 A17 K18 E19L11-A15 HydrophobicContact CB-CB 4.27Å; L11-A15 HydrophobicContact CD2-CB 4.13Å; P12-A15 HydrophobicContact CB-CB 4.04Å; P12-A15 HydrophobicContact CG-CB 4.08Å; P12-A15 WeakPolarHBondContact O-CA 3.15Å; P12-A15 WeakPolarHBondContact O-CB 3.11Å; P12-A15 PolarHBondContact O-N 3.01Å; A15-A17 PolarHBondContact O-N 3.42Å; A15-K18 CarbonylContact O-C 3.59Å; A15-K18 WeakPolarHBondContact O-CB 3.46Å; A15-K18 PolarHBondContact O-N 2.71Å; A15-K18 VanDerWaalsContact O-N 3.14Å; A15-E19 WeakPolarHBondContact O-CG 3.13Å; A15-E19 PolarHBondContact O-N 3.46Å
16A73.3Confident69.7Low0 Ų082.1 Ų82.10%040%0.397CS..Hα-helixtrans-63.6-43.4176.700000111.5L11 P12 K18 E19 F20 E98L11-A16 HydrophobicContact CB-CB 4.02Å; L11-A16 HydrophobicContact CD1-CB 4.12Å; P12-A16 PolarHBondContact O-N 2.77Å; A16-K18 VanDerWaalsContact C-N 3.32Å; A16-K18 PolarHBondContact O-N 3.49Å; A16-E19 PolarHBondContact O-N 2.73Å; A16-F20 PolarHBondContact O-N 3.48Å; A16-E98 WeakPolarHBondContact CB-O 3.32Å
17A79.1Confident72.7Confident20 Ų2083 Ų8317%0.16539%0.385CS..Hα-helixtrans-58.8-46.2172.400000110.7D13 A15 E19 F20 Y21 F104D13-A17 VanDerWaalsContact O-CB 3.3Å; D13-A17 WeakPolarHBondContact O-CB 3.34Å; D13-A17 PolarHBondContact O-N 3.25Å; A15-A17 PolarHBondContact O-N 3.42Å; A17-E19 PolarHBondContact O-N 3.12Å; A17-F20 PolarHBondContact O-N 2.77Å; A17-Y21 HydrophobicContact CB-CD2 4.25Å; A17-Y21 HydrophobicContact CB-CE2 4.15Å; A17-Y21 WeakPolarHBondContact O-CB 2.98Å; A17-Y21 WeakPolarHBondContact O-CD2 3.06Å; A17-Y21 PolarHBondContact O-N 3.46Å; A17-F104 HydrophobicContact CB-CE2 4.42Å; A17-F104 HydrophobicContact CB-CZ 4.38Å
18K85.1Confident75.2Confident106 Ų10674.9 Ų74.946%0.46136%0.36SS..Hα-helixtrans-61.8-44.4178.9178.3-177.1-179.7-173.70112.2W14 A15 A16 Y21 Q22W14-K18 HydrophobicContact CE3-CD 3.94Å; W14-K18 HydrophobicContact CZ3-CD 3.71Å; W14-K18 WeakPolarHBondContact O-CB 3.06Å; W14-K18 PolarHBondContact O-N 3.35Å; A15-K18 CarbonylContact O-C 3.59Å; A15-K18 WeakPolarHBondContact O-CB 3.46Å; A15-K18 PolarHBondContact O-N 2.71Å; A15-K18 VanDerWaalsContact O-N 3.14Å; A16-K18 VanDerWaalsContact C-N 3.32Å; A16-K18 PolarHBondContact O-N 3.49Å; K18-Y21 PolarHBondContact O-N 2.9Å; K18-Q22 HydrophobicContact CG-CG 4.26Å; K18-Q22 VanDerWaalsContact O-CB 3.24Å; K18-Q22 WeakPolarHBondContact O-CB 3.24Å; K18-Q22 WeakPolarHBondContact O-CG 3.36Å; K18-Q22 PolarHBondContact O-N 2.9Å
19E88.9Confident77.7Confident81 Ų8169.4 Ų69.438%0.37934%0.338SS..Hα-helixtrans-61.6-46.5177.4-74.3-176.4-176.600111.5A15 A16 A17 Q22 K23 Y97A15-E19 WeakPolarHBondContact O-CG 3.13Å; A15-E19 PolarHBondContact O-N 3.46Å; A16-E19 PolarHBondContact O-N 2.73Å; A17-E19 PolarHBondContact O-N 3.12Å; E19-Q22 PolarHBondContact O-N 2.73Å; E19-K23 PolarHBondContact O-N 3.39Å; E19-Y97 HydrophobicContact CB-CD1 3.78Å; E19-Y97 HydrophobicContact CB-CE1 3.79Å
20F92.7Very high80.1Confident0 Ų065.3 Ų65.30%032%0.316CS..Hα-helixtrans-57.6-52.8173.8171.6-99.3000111.4A16 A17 Q22 K23 Y24 P26 V52 Y97 F104 V106A16-F20 PolarHBondContact O-N 3.48Å; A17-F20 PolarHBondContact O-N 2.77Å; F20-Q22 VanDerWaalsContact C-N 3.26Å; F20-Q22 PolarHBondContact O-N 3.01Å; F20-K23 PolarHBondContact O-N 3.36Å; F20-Y24 AromaticContact CD2-CD2 3.91Å; F20-Y24 HydrophobicContact CD2-CD2 3.91Å; F20-Y24 HydrophobicContact CD2-CG 4.35Å; F20-Y24 AromaticContact CE2-CD2 3.96Å; F20-Y24 HydrophobicContact CE2-CD2 3.96Å; F20-Y24 AromaticContact CE2-CG 3.97Å; F20-Y24 HydrophobicContact CE2-CG 3.97Å; F20-Y24 WeakPolarHBondContact O-CA 3.45Å; F20-Y24 WeakPolarHBondContact O-CB 3.32Å; F20-Y24 PolarHBondContact O-N 3.06Å; F20-P26 HydrophobicContact CE1-CB 4.46Å; F20-P26 HydrophobicContact CE1-CG 4.14Å; F20-V52 HydrophobicContact CD2-CG2 4.41Å; F20-V52 HydrophobicContact CE2-CB 4.04Å; F20-V52 HydrophobicContact CE2-CG1 4.3Å; F20-V52 HydrophobicContact CE2-CG2 3.63Å; F20-V52 HydrophobicContact CZ-CB 4.11Å; F20-V52 HydrophobicContact CZ-CG1 3.85Å; F20-V52 HydrophobicContact CZ-CG2 3.88Å; F20-Y97 HydrophobicContact CB-CD2 3.83Å; F20-Y97 HydrophobicContact CB-CE2 4.23Å; F20-Y97 HydrophobicContact CB-CG 4.01Å; F20-Y97 AromaticContact CD2-CD2 3.91Å; F20-Y97 HydrophobicContact CD2-CD2 3.91Å; F20-Y97 AromaticContact CD2-CE2 4Å; F20-Y97 HydrophobicContact CD2-CE2 4Å; F20-Y97 HydrophobicContact CG-CD2 4.35Å; F20-F104 HydrophobicContact CB-CD1 4.37Å; F20-F104 HydrophobicContact CB-CG 4.25Å; F20-F104 AromaticContact CD1-CD1 3.67Å; F20-F104 HydrophobicContact CD1-CD1 3.67Å; F20-F104 AromaticContact CD1-CE1 3.85Å; F20-F104 HydrophobicContact CD1-CE1 3.85Å; F20-F104 HydrophobicContact CD1-CG 4.36Å; F20-F104 HydrophobicContact CD2-CB 4.07Å; F20-F104 HydrophobicContact CD2-CD1 4.17Å; F20-F104 HydrophobicContact CD2-CG 4.31Å; F20-F104 HydrophobicContact CE1-CD1 4.01Å; F20-F104 HydrophobicContact CE1-CE1 4.25Å; F20-F104 HydrophobicContact CE2-CD1 4.48Å; F20-F104 HydrophobicContact CG-CB 4.25Å; F20-F104 AromaticContact CG-CD1 3.77Å; F20-F104 HydrophobicContact CG-CD1 3.77Å; F20-F104 HydrophobicContact CG-CE1 4.32Å; F20-F104 HydrophobicContact CG-CG 4.01Å; F20-F104 HydrophobicContact CZ-CD1 4.42Å; F20-V106 HydrophobicContact CD2-CG2 4.39Å; F20-V106 HydrophobicContact CE2-CG2 4.15Å
21Y92.1Very high81.7Confident104 Ų10459.4 Ų59.441%0.40829%0.294SS..Hα-helixtrans-67.8-24-177.9-72.9-64.6000113.6A17 K18 Y24 P26 R44A17-Y21 HydrophobicContact CB-CD2 4.25Å; A17-Y21 HydrophobicContact CB-CE2 4.15Å; A17-Y21 WeakPolarHBondContact O-CB 2.98Å; A17-Y21 WeakPolarHBondContact O-CD2 3.06Å; A17-Y21 PolarHBondContact O-N 3.46Å; K18-Y21 PolarHBondContact O-N 2.9Å; Y21-Y24 CarbonylContact C-O 3.57Å; Y21-Y24 VanDerWaalsContact O-O 3.12Å; Y21-P26 HydrophobicContact CD1-CG 4.1Å; Y21-P26 HydrophobicContact CE1-CG 3.68Å; Y21-R44 PolarHBondContact O-NE 3.23Å; Y21-R44 PolarHBondContact O-NH2 2.79Å
22Q93.8Very high83.4Confident122 Ų12266.2 Ų66.257%0.5732%0.316SS*.Hα-helixtrans-73.2-37.6173-81179.5-2.700112.3K18 E19 F20 R44K18-Q22 HydrophobicContact CG-CG 4.26Å; K18-Q22 VanDerWaalsContact O-CB 3.24Å; K18-Q22 WeakPolarHBondContact O-CB 3.24Å; K18-Q22 WeakPolarHBondContact O-CG 3.36Å; K18-Q22 PolarHBondContact O-N 2.9Å; E19-Q22 PolarHBondContact O-N 2.73Å; F20-Q22 VanDerWaalsContact C-N 3.26Å; F20-Q22 PolarHBondContact O-N 3.01Å; Q22-R44 WeakPolarHBondContact O-CD 3.49Å
23K95.8Very high84.3Confident72 Ų7265.4 Ų65.431%0.31332%0.318SS..Hα-helixtrans-90.2-34.6-178.4-164.6179.7-177.7-174.40112.7E19 F20 H43 R44 D95 Y97E19-K23 PolarHBondContact O-N 3.39Å; F20-K23 PolarHBondContact O-N 3.36Å; K23-H43 WeakPolarHBondContact CE-NE2 3.36Å; K23-H43 WeakPolarHBondContact CG-NE2 3.2Å; K23-R44 PolarHBondContact O-N 3.47Å; K23-D95 WeakPolarHBondContact CE-OD2 3.1Å; K23-D95 IonicContact NZ-OD1 3.75Å; K23-D95 PolarHBondContact NZ-OD1 3.09Å; K23-D95 IonicContact NZ-OD2 3.43Å; K23-D95 PolarHBondContact NZ-OD2 3.26Å; K23-Y97 WeakPolarHBondContact CD-OH 3.04Å
24Y97Very high84.7Confident4 Ų470 Ų702%0.01635%0.348CS..EExtended strand (participates in β ladder)trans-123.4148.1-173.2-65.3-79.7000112.8F20 Y21 V42 H43 R44 F50 D95 Y97 V106F20-Y24 AromaticContact CD2-CD2 3.91Å; F20-Y24 HydrophobicContact CD2-CD2 3.91Å; F20-Y24 HydrophobicContact CD2-CG 4.35Å; F20-Y24 AromaticContact CE2-CD2 3.96Å; F20-Y24 HydrophobicContact CE2-CD2 3.96Å; F20-Y24 AromaticContact CE2-CG 3.97Å; F20-Y24 HydrophobicContact CE2-CG 3.97Å; F20-Y24 WeakPolarHBondContact O-CA 3.45Å; F20-Y24 WeakPolarHBondContact O-CB 3.32Å; F20-Y24 PolarHBondContact O-N 3.06Å; Y21-Y24 CarbonylContact C-O 3.57Å; Y21-Y24 VanDerWaalsContact O-O 3.12Å; Y24-V42 CarbonylContact C-O 3.58Å; Y24-V42 WeakPolarHBondContact CA-O 3.2Å; Y24-H43 HydrophobicContact CD1-CB 4.04Å; Y24-H43 HydrophobicContact CE1-CB 3.76Å; Y24-H43 AromaticContact CE1-CD2 3.68Å; Y24-H43 AromaticContact CZ-CD2 3.8Å; Y24-R44 PolarHBondContact O-NH2 3.44Å; Y24-F50 HydrophobicContact CD1-CD2 4.39Å; Y24-F50 AromaticContact CE1-CD2 3.74Å; Y24-F50 HydrophobicContact CE1-CD2 3.74Å; Y24-F50 HydrophobicContact CE1-CE2 4.13Å; Y24-F50 HydrophobicContact CE1-CG 4.4Å; Y24-D95 HydrophobicContact CE2-CB 4.33Å; Y24-D95 VanDerWaalsContact CE2-OD2 3.32Å; Y24-D95 WeakPolarHBondContact CE2-OD2 3.26Å; Y24-D95 VanDerWaalsContact CZ-OD2 3.31Å; Y24-D95 PolarHBondContact OH-OD2 3.43Å; Y24-Y97 HydrophobicContact CD2-CE2 4.16Å; Y24-Y97 AromaticContact CE2-CE2 4Å; Y24-Y97 HydrophobicContact CE2-CE2 4Å; Y24-V106 HydrophobicContact CD2-CG2 4.26Å; Y24-V106 HydrophobicContact CE1-CG1 4.02Å; Y24-V106 HydrophobicContact CE2-CG1 4.48Å; Y24-V106 HydrophobicContact CE2-CG2 3.98Å
25D94.4Very high85.2Confident48 Ų4865.4 Ų65.426%0.25734%0.342SS..EExtended strand (participates in β ladder)trans-114.4101174.9-164.331.5000110.3K27 C41 V42 R44D25-K27 VanDerWaalsContact OD2-CE 3.28Å; D25-K27 WeakPolarHBondContact OD2-CE 3.45Å; D25-K27 IonicContact OD2-NZ 3.57Å; D25-K27 PolarHBondContact OD2-NZ 2.74Å; D25-C41 WeakPolarHBondContact O-CA 3.45Å; D25-V42 PolarHBondContact N-O 3.22Å; D25-V42 PolarHBondContact O-N 2.85Å; D25-R44 HydrophobicContact CB-CG 4.28Å; D25-R44 IonicContact OD1-CZ 2.59Å; D25-R44 IonicContact OD1-NH1 2.65Å; D25-R44 PolarHBondContact OD1-NH1 3.33Å; D25-R44 IonicContact OD1-NH2 3.82Å; D25-R44 PolarHBondContact OD1-NH2 3.14Å; D25-R44 IonicContact OD2-NH1 2.87Å
26P93.7Very high86Confident20 Ų2066.1 Ų66.113%0.1335%0.346CS..EExtended strand (participates in β ladder)trans-69.8143.6-17926-30.5000112F20 Y21F20-P26 HydrophobicContact CE1-CB 4.46Å; F20-P26 HydrophobicContact CE1-CG 4.14Å; Y21-P26 HydrophobicContact CD1-CG 4.1Å; Y21-P26 HydrophobicContact CE1-CG 3.68Å
27K94.8Very high86.8Confident73 Ų7367.6 Ų67.632%0.31736%0.355SS..EExtended strand (participates in β ladder)trans-121.1-137.8-174-57.1-62.8176.5-174.30110.3D25 R39 R40 V42D25-K27 VanDerWaalsContact OD2-CE 3.28Å; D25-K27 WeakPolarHBondContact OD2-CE 3.45Å; D25-K27 IonicContact OD2-NZ 3.57Å; D25-K27 PolarHBondContact OD2-NZ 2.74Å; K27-R39 VanDerWaalsContact O-CZ 3.26Å; K27-R39 PolarHBondContact O-NE 3.38Å; K27-R39 PolarHBondContact O-NH2 3.49Å; K27-R40 WeakPolarHBondContact CA-O 3.33Å; K27-R40 HydrophobicContact CB-CB 4.34Å; K27-R40 WeakPolarHBondContact CB-O 3.5Å; K27-R40 PolarHBondContact N-O 3.12Å; K27-V42 HydrophobicContact CG-CG2 4.05Å
28D90.9Very high87.4Confident77 Ų7768.5 Ų68.541%0.41236%0.359SS..EExtended strand (participates in β ladder)trans-65.5154-179.850.6-72.4000112.8I30 R39 R40D28-I30 WeakPolarHBondContact OD2-CG2 3.11Å; D28-R39 CarbonylContact O-C 3.45Å; D28-R39 VanDerWaalsContact O-CA 3.27Å; D28-R39 WeakPolarHBondContact O-CA 3.03Å; D28-R39 WeakPolarHBondContact O-CB 3.42Å; D28-R40 PolarHBondContact O-N 3.39Å; D28-R40 IonicContact OD1-CZ 3.07Å; D28-R40 IonicContact OD1-NE 3.13Å; D28-R40 PolarHBondContact OD1-NE 2.72Å; D28-R40 IonicContact OD1-NH2 3.49Å; D28-R40 PolarHBondContact OD1-NH2 2.86Å; D28-R40 IonicContact OD2-NE 2.67Å
29V91.1Very high87.8Confident58 Ų5867.1 Ų67.135%0.35235%0.351SS..EExtended strand (participates in β ladder)trans-80.9124.5173.7176.70000108G31 R32 V37 R39V29-G31 WeakPolarHBondContact CG1-O 3.43Å; V29-R32 HydrophobicContact CG1-CG 3.91Å; V29-V37 HydrophobicContact CB-CG2 4.47Å; V29-V37 HydrophobicContact CG1-CG2 3.66Å; V29-V37 HydrophobicContact CG2-CG2 4.01Å; V29-R39 HydrophobicContact CG2-CG 4.04Å
30I87.9Confident88.2Confident82 Ų8266 Ų6642%0.42134%0.343SS..EExtended strand (participates in β ladder)trans-108.4-16.218062.7177.6000112.4D28 V38 R40 A51 L109D28-I30 WeakPolarHBondContact OD2-CG2 3.11Å; I30-V38 HydrophobicContact CD1-CG1 3.9Å; I30-V38 HydrophobicContact CG1-CB 4.16Å; I30-V38 HydrophobicContact CG1-CG1 3.73Å; I30-V38 WeakPolarHBondContact CG1-O 3.1Å; I30-V38 PolarHBondContact N-O 2.68Å; I30-R40 HydrophobicContact CG2-CB 4.2Å; I30-A51 HydrophobicContact CD1-CB 3.94Å; I30-L109 HydrophobicContact CD1-CD1 3.93Å
31G82.4Confident88.3Confident21 Ų2166 Ų6622%0.21634%0.343CS..EExtended strand (participates in β ladder)trans-157.8155.9176.400000112.6V29 V38V29-G31 WeakPolarHBondContact CG1-O 3.43Å; G31-V38 PolarHBondContact N-O 3.45Å; G31-V38 VanDerWaalsContact N-O 3.09Å; G31-V38 PolarHBondContact O-N 2.76Å
32R80.1Confident88.6Confident199 Ų19962.2 Ų62.275%0.75133%0.331SS*.EExtended strand (participates in β ladder)trans-137.7126.5174.9-67.6-177.2-179.6-86.71.4109.1V29 V37V29-R32 HydrophobicContact CG1-CG 3.91Å; R32-V37 HydrophobicContact CG-CG2 4.35Å
33G69.8Low88.8Confident44 Ų4457.8 Ų57.845%0.45431%0.31SS..  trans-104.9-173167.600000111.3S36G33-S36 PolarHBondContact N-O 3.42Å
34V68.6Low88.8Confident159 Ų15960.5 Ų60.596%0.96432%0.318SS*.SBendtrans-66.5-46.2-179.5179.40000111.7
35S71.8Confident88.8Confident73 Ų7364.6 Ų64.651%0.5135%0.353SS..SBendtrans-120.516.1-179.8550000112.9E56S35-E56 PolarHBondContact O-N 2.84Å; S35-E56 VanDerWaalsContact O-N 3.12Å
36S83.8Confident88.9Confident25 Ų2566.2 Ų66.218%0.17537%0.365CS..EExtended strand (participates in β ladder)trans-143.5152.2-176.366.60000113.7G33 I54G33-S36 PolarHBondContact N-O 3.42Å; S36-I54 CarbonylContact C-O 3.58Å; S36-I54 WeakPolarHBondContact CA-O 3.38Å; S36-I54 WeakPolarHBondContact CB-O 3.49Å
37V88.6Confident89Confident32 Ų3267.6 Ų67.619%0.19438%0.382CS..EExtended strand (participates in β ladder)trans-126.6131.6170.7630000109.5V29 R32 R39 I54V29-V37 HydrophobicContact CB-CG2 4.47Å; V29-V37 HydrophobicContact CG1-CG2 3.66Å; V29-V37 HydrophobicContact CG2-CG2 4.01Å; R32-V37 HydrophobicContact CG-CG2 4.35Å; V37-R39 HydrophobicContact CG2-CG 4.19Å; V37-I54 HydrophobicContact CG1-CB 3.88Å; V37-I54 HydrophobicContact CG1-CD1 4.27Å; V37-I54 HydrophobicContact CG1-CG1 4.41Å; V37-I54 PolarHBondContact N-O 3.09Å; V37-I54 PolarHBondContact O-N 2.88Å
38V91.2Very high89.1Confident39 Ų3968.4 Ų68.424%0.23639%0.39CS..EExtended strand (participates in β ladder)trans-102.1125175.4-1700000108.6I30 G31 A51 V52 K53I30-V38 HydrophobicContact CD1-CG1 3.9Å; I30-V38 HydrophobicContact CG1-CB 4.16Å; I30-V38 HydrophobicContact CG1-CG1 3.73Å; I30-V38 WeakPolarHBondContact CG1-O 3.1Å; I30-V38 PolarHBondContact N-O 2.68Å; G31-V38 PolarHBondContact N-O 3.45Å; G31-V38 VanDerWaalsContact N-O 3.09Å; G31-V38 PolarHBondContact O-N 2.76Å; V38-A51 HydrophobicContact CG1-CB 4.24Å; V38-V52 CarbonylContact C-O 3.37Å; V38-V52 VanDerWaalsContact CA-O 3.29Å; V38-V52 WeakPolarHBondContact CA-O 3.36Å; V38-K53 HydrophobicContact CG2-CB 4.25Å; V38-K53 HydrophobicContact CG2-CG 4.19Å
39R94.6Very high89.4Confident77 Ų7767.6 Ų67.629%0.29138%0.384SS..EExtended strand (participates in β ladder)trans-122.9147.1179.1-60.7-178.373.3167.40.4110.2K27 D28 V29 V37 A51 V52K27-R39 VanDerWaalsContact O-CZ 3.26Å; K27-R39 PolarHBondContact O-NE 3.38Å; K27-R39 PolarHBondContact O-NH2 3.49Å; D28-R39 CarbonylContact O-C 3.45Å; D28-R39 VanDerWaalsContact O-CA 3.27Å; D28-R39 WeakPolarHBondContact O-CA 3.03Å; D28-R39 WeakPolarHBondContact O-CB 3.42Å; V29-R39 HydrophobicContact CG2-CG 4.04Å; V37-R39 HydrophobicContact CG2-CG 4.19Å; R39-A51 CarbonylContact O-C 3.59Å; R39-A51 WeakPolarHBondContact O-CA 3.45Å; R39-V52 HydrophobicContact CB-CG1 3.99Å; R39-V52 PolarHBondContact N-O 2.84Å; R39-V52 PolarHBondContact O-N 3.19Å
40R96.4Very high89.7Confident56 Ų5666.3 Ų66.321%0.21137%0.374CS..EExtended strand (participates in β ladder)trans-65.8140.6161.1-177.2175.361.391.51.4108.4K27 D28 I30 E49 F50 L109K27-R40 WeakPolarHBondContact CA-O 3.33Å; K27-R40 HydrophobicContact CB-CB 4.34Å; K27-R40 WeakPolarHBondContact CB-O 3.5Å; K27-R40 PolarHBondContact N-O 3.12Å; D28-R40 PolarHBondContact O-N 3.39Å; D28-R40 IonicContact OD1-CZ 3.07Å; D28-R40 IonicContact OD1-NE 3.13Å; D28-R40 PolarHBondContact OD1-NE 2.72Å; D28-R40 IonicContact OD1-NH2 3.49Å; D28-R40 PolarHBondContact OD1-NH2 2.86Å; D28-R40 IonicContact OD2-NE 2.67Å; I30-R40 HydrophobicContact CG2-CB 4.2Å; R40-E49 IonicContact CZ-OE1 3.66Å; R40-E49 IonicContact NH1-OE1 3.16Å; R40-E49 PolarHBondContact NH1-OE1 3.13Å; R40-F50 CarbonylContact C-O 3.52Å; R40-F50 WeakPolarHBondContact CA-O 3.26Å; R40-L109 HydrophobicContact CG-CD1 4.41Å; R40-L109 HydrophobicContact CG-CD2 4.02Å
41C96.4Very high90.1Very high0 Ų062.9 Ų62.90%036%0.357CS..EExtended strand (participates in β ladder)trans-136.4160.1171.764.90000111D25 E49 F50 V52D25-C41 WeakPolarHBondContact O-CA 3.45Å; C41-E49 WeakPolarHBondContact O-CA 3.33Å; C41-F50 PolarHBondContact N-O 3.28Å; C41-F50 PolarHBondContact O-N 3.48Å; C41-V52 HydrophobicContact CB-CG1 4.04Å
42V97.5Very high90.7Very high26 Ų2661.9 Ų61.916%0.15835%0.347CS..EExtended strand (participates in β ladder)trans-121.5127.2-179.5-175.90000109Y24 D25 K27 R44 D48 E49Y24-V42 CarbonylContact C-O 3.58Å; Y24-V42 WeakPolarHBondContact CA-O 3.2Å; D25-V42 PolarHBondContact N-O 3.22Å; D25-V42 PolarHBondContact O-N 2.85Å; K27-V42 HydrophobicContact CG-CG2 4.05Å; V42-R44 PolarHBondContact O-N 2.82Å; V42-D48 CarbonylContact C-O 3.54Å; V42-D48 WeakPolarHBondContact CA-O 3.37Å; V42-E49 HydrophobicContact CG2-CG 4.29Å
43H97.4Very high91.3Very high29 Ų2953.8 Ų53.813%0.13432%0.317CS..EExtended strand (participates in β ladder)trans-68.7119.4173.5-177-102.9000109.7K23 Y24 A45 T46 G47 D48 F50K23-H43 WeakPolarHBondContact CE-NE2 3.36Å; K23-H43 WeakPolarHBondContact CG-NE2 3.2Å; Y24-H43 HydrophobicContact CD1-CB 4.04Å; Y24-H43 HydrophobicContact CE1-CB 3.76Å; Y24-H43 AromaticContact CE1-CD2 3.68Å; Y24-H43 AromaticContact CZ-CD2 3.8Å; H43-A45 VanDerWaalsContact C-N 3.3Å; H43-A45 PolarHBondContact O-N 3.32Å; H43-T46 PolarHBondContact ND1-N 2.98Å; H43-T46 PolarHBondContact ND1-OG1 2.74Å; H43-T46 PolarHBondContact O-N 3.49Å; H43-G47 WeakPolarHBondContact O-CA 3.31Å; H43-G47 PolarHBondContact O-N 3.25Å; H43-D48 PolarHBondContact N-O 3.11Å; H43-F50 HydrophobicContact CB-CD2 4.18Å; H43-F50 HydrophobicContact CB-CE2 3.73Å
44R96.6Very high92.3Very high128 Ų12852.7 Ų52.748%0.48330%0.301SS..THydrogen-bonded Turntrans-63.4-33.6-167.1-68.5-169.5-175.3-76.8-8.4113.6Y21 Q22 K23 Y24 D25 V42Y21-R44 PolarHBondContact O-NE 3.23Å; Y21-R44 PolarHBondContact O-NH2 2.79Å; Q22-R44 WeakPolarHBondContact O-CD 3.49Å; K23-R44 PolarHBondContact O-N 3.47Å; Y24-R44 PolarHBondContact O-NH2 3.44Å; D25-R44 HydrophobicContact CB-CG 4.28Å; D25-R44 IonicContact OD1-CZ 2.59Å; D25-R44 IonicContact OD1-NH1 2.65Å; D25-R44 PolarHBondContact OD1-NH1 3.33Å; D25-R44 IonicContact OD1-NH2 3.82Å; D25-R44 PolarHBondContact OD1-NH2 3.14Å; D25-R44 IonicContact OD2-NH1 2.87Å; V42-R44 PolarHBondContact O-N 2.82Å
45A96.3Very high93.1Very high90 Ų9046 Ų4674%0.74426%0.259SS*.THydrogen-bonded Turntrans-83.1-33.6-175.600000113.4H43H43-A45 VanDerWaalsContact C-N 3.3Å; H43-A45 PolarHBondContact O-N 3.32Å
46T96.8Very high93.5Very high83 Ų8347.9 Ų47.951%0.50926%0.26SS..THydrogen-bonded Turntrans-104.1-24.2-174.961.40000113.1H43 D48H43-T46 PolarHBondContact ND1-N 2.98Å; H43-T46 PolarHBondContact ND1-OG1 2.74Å; H43-T46 PolarHBondContact O-N 3.49Å; T46-D48 WeakPolarHBondContact CB-OD2 3.27Å; T46-D48 VanDerWaalsContact OG1-CG 3.3Å; T46-D48 PolarHBondContact OG1-N 3.27Å; T46-D48 PolarHBondContact OG1-OD2 2.95Å
47G95.8Very high92.9Very high48 Ų4847 Ų4750%0.49525%0.253SS..  trans80.42.9-172.900000114H43H43-G47 WeakPolarHBondContact O-CA 3.31Å; H43-G47 PolarHBondContact O-N 3.25Å
48D96.4Very high91.7Very high90 Ų9048.3 Ų48.348%0.48126%0.261SS..  trans-69.8146.4179.4-59.9-43.5000111.4V42 H43 T46 F50V42-D48 CarbonylContact C-O 3.54Å; V42-D48 WeakPolarHBondContact CA-O 3.37Å; H43-D48 PolarHBondContact N-O 3.11Å; T46-D48 WeakPolarHBondContact CB-OD2 3.27Å; T46-D48 VanDerWaalsContact OG1-CG 3.3Å; T46-D48 PolarHBondContact OG1-N 3.27Å; T46-D48 PolarHBondContact OG1-OD2 2.95Å; D48-F50 HydrophobicContact CB-CE2 3.61Å; D48-F50 HydrophobicContact CB-CZ 3.91Å
49E97.2Very high90Very high60 Ų6048.7 Ų48.728%0.2827%0.269SS..EExtended strand (participates in β ladder)trans-103.5137.3-176.1-56.4-168.1112.100112.1R40 C41 V42 L109 R111R40-E49 IonicContact CZ-OE1 3.66Å; R40-E49 IonicContact NH1-OE1 3.16Å; R40-E49 PolarHBondContact NH1-OE1 3.13Å; C41-E49 WeakPolarHBondContact O-CA 3.33Å; V42-E49 HydrophobicContact CG2-CG 4.29Å; E49-L109 HydrophobicContact CB-CD2 3.79Å; E49-R111 IonicContact OE2-CZ 3.66Å; E49-R111 IonicContact OE2-NH1 3.3Å; E49-R111 PolarHBondContact OE2-NH1 3.04Å; E49-R111 IonicContact OE2-NH2 3.18Å; E49-R111 PolarHBondContact OE2-NH2 3.41Å
50F97.6Very high88Confident32 Ų3254.9 Ų54.914%0.1430%0.301CS..EExtended strand (participates in β ladder)trans-135.9173.8-176.7-61.5-81.8000110.7Y24 R40 C41 H43 D48 I94 V106 F107Y24-F50 HydrophobicContact CD1-CD2 4.39Å; Y24-F50 AromaticContact CE1-CD2 3.74Å; Y24-F50 HydrophobicContact CE1-CD2 3.74Å; Y24-F50 HydrophobicContact CE1-CE2 4.13Å; Y24-F50 HydrophobicContact CE1-CG 4.4Å; R40-F50 CarbonylContact C-O 3.52Å; R40-F50 WeakPolarHBondContact CA-O 3.26Å; C41-F50 PolarHBondContact N-O 3.28Å; C41-F50 PolarHBondContact O-N 3.48Å; H43-F50 HydrophobicContact CB-CD2 4.18Å; H43-F50 HydrophobicContact CB-CE2 3.73Å; D48-F50 HydrophobicContact CB-CE2 3.61Å; D48-F50 HydrophobicContact CB-CZ 3.91Å; F50-I94 HydrophobicContact CD1-CG1 4.08Å; F50-I94 HydrophobicContact CE1-CG1 4.09Å; F50-I94 HydrophobicContact CE1-CG2 4.14Å; F50-V106 HydrophobicContact CB-CG1 3.68Å; F50-V106 HydrophobicContact CD1-CG1 4.34Å; F50-V106 HydrophobicContact CG-CG1 4.01Å; F50-F107 WeakPolarHBondContact CB-O 3.39Å
51A96.9Very high86.1Confident9 Ų963 Ų637%0.07433%0.332CS..EExtended strand (participates in β ladder)trans-110.5134166.600000109.5I30 V38 R39 V106 F107 L109I30-A51 HydrophobicContact CD1-CB 3.94Å; V38-A51 HydrophobicContact CG1-CB 4.24Å; R39-A51 CarbonylContact O-C 3.59Å; R39-A51 WeakPolarHBondContact O-CA 3.45Å; A51-V106 CarbonylContact O-C 3.58Å; A51-V106 WeakPolarHBondContact O-CA 3.45Å; A51-F107 PolarHBondContact N-O 3.46Å; A51-F107 PolarHBondContact O-N 2.88Å; A51-L109 HydrophobicContact CB-CD1 4.19Å
52V95.8Very high84.7Confident0 Ų066.6 Ų66.60%035%0.35CS..EExtended strand (participates in β ladder)trans-112.2121.617261.10000109.8F20 V38 R39 C41 I54 F104 L105 V106F20-V52 HydrophobicContact CD2-CG2 4.41Å; F20-V52 HydrophobicContact CE2-CB 4.04Å; F20-V52 HydrophobicContact CE2-CG1 4.3Å; F20-V52 HydrophobicContact CE2-CG2 3.63Å; F20-V52 HydrophobicContact CZ-CB 4.11Å; F20-V52 HydrophobicContact CZ-CG1 3.85Å; F20-V52 HydrophobicContact CZ-CG2 3.88Å; V38-V52 CarbonylContact C-O 3.37Å; V38-V52 VanDerWaalsContact CA-O 3.29Å; V38-V52 WeakPolarHBondContact CA-O 3.36Å; R39-V52 HydrophobicContact CB-CG1 3.99Å; R39-V52 PolarHBondContact N-O 2.84Å; R39-V52 PolarHBondContact O-N 3.19Å; C41-V52 HydrophobicContact CB-CG1 4.04Å; V52-I54 HydrophobicContact CG1-CD1 4.37Å; V52-I54 HydrophobicContact CG1-CG1 4.23Å; V52-I54 HydrophobicContact CG2-CG1 3.95Å; V52-F104 HydrophobicContact CG2-CB 4.08Å; V52-F104 HydrophobicContact CG2-CD1 4.32Å; V52-L105 CarbonylContact C-O 3.56Å; V52-L105 VanDerWaalsContact CA-O 3.3Å; V52-L105 WeakPolarHBondContact CA-O 3.37Å; V52-V106 HydrophobicContact CG2-CG2 4.3Å
53K92.4Very high83.7Confident30 Ų3067.3 Ų67.313%0.1336%0.357CS..EExtended strand (participates in β ladder)trans-88113.4166.7-175.2-179.8176.8-174.30106.9V38 M55 E77 L105 F107V38-K53 HydrophobicContact CG2-CB 4.25Å; V38-K53 HydrophobicContact CG2-CG 4.19Å; K53-M55 HydrophobicContact CD-CG 4.45Å; K53-M55 HydrophobicContact CD-SD 4.24Å; K53-M55 HydrophobicContact CG-CG 4.08Å; K53-M55 HydrophobicContact CG-SD 4.48Å; K53-E77 IonicContact NZ-OE1 3.1Å; K53-E77 PolarHBondContact NZ-OE1 2.8Å; K53-E77 VanDerWaalsContact NZ-OE1 3.16Å; K53-E77 IonicContact NZ-OE2 3.47Å; K53-L105 HydrophobicContact CB-CB 4.38Å; K53-L105 PolarHBondContact N-O 3.28Å; K53-L105 PolarHBondContact O-N 3.49Å; K53-F107 HydrophobicContact CB-CD2 4.44Å; K53-F107 HydrophobicContact CB-CE2 3.95Å; K53-F107 HydrophobicContact CD-CE2 4.49Å
54I90.3Very high82.9Confident20 Ų2071.3 Ų71.310%0.10339%0.385CS..EExtended strand (participates in β ladder)trans-101114.3177.4-49.9175.2000106.5S36 V37 V52 M103 F104S36-I54 CarbonylContact C-O 3.58Å; S36-I54 WeakPolarHBondContact CA-O 3.38Å; S36-I54 WeakPolarHBondContact CB-O 3.49Å; V37-I54 HydrophobicContact CG1-CB 3.88Å; V37-I54 HydrophobicContact CG1-CD1 4.27Å; V37-I54 HydrophobicContact CG1-CG1 4.41Å; V37-I54 PolarHBondContact N-O 3.09Å; V37-I54 PolarHBondContact O-N 2.88Å; V52-I54 HydrophobicContact CG1-CD1 4.37Å; V52-I54 HydrophobicContact CG1-CG1 4.23Å; V52-I54 HydrophobicContact CG2-CG1 3.95Å; I54-M103 CarbonylContact C-O 3.51Å; I54-M103 WeakPolarHBondContact CA-O 3.33Å; I54-F104 HydrophobicContact CB-CD1 4.44Å; I54-F104 HydrophobicContact CD1-CD1 4.27Å; I54-F104 HydrophobicContact CD1-CE1 4.15Å; I54-F104 HydrophobicContact CG1-CD1 3.85Å; I54-F104 HydrophobicContact CG1-CE1 4.12Å; I54-F104 HydrophobicContact CG2-CD1 4.04Å; I54-F104 HydrophobicContact CG2-CE1 3.77Å; I54-F104 HydrophobicContact CG2-CZ 4.32Å
55M85.4Confident82.2Confident18 Ų1872.4 Ų72.49%0.08940%0.396CS..EExtended strand (participates in β ladder)trans-106130.8179.1-60.2177.36000108.7K53 T74 F102 M103 L105K53-M55 HydrophobicContact CD-CG 4.45Å; K53-M55 HydrophobicContact CD-SD 4.24Å; K53-M55 HydrophobicContact CG-CG 4.08Å; K53-M55 HydrophobicContact CG-SD 4.48Å; M55-T74 HydrophobicContact CE-CG2 4.02Å; M55-T74 HydrophobicContact SD-CG2 4.12Å; M55-F102 CarbonylContact O-C 3.6Å; M55-F102 VanDerWaalsContact O-CA 3.31Å; M55-F102 WeakPolarHBondContact O-CA 3.09Å; M55-M103 HydrophobicContact CB-CB 4.35Å; M55-M103 HydrophobicContact CB-CE 4.44Å; M55-M103 HydrophobicContact CE-CE 4.36Å; M55-M103 PolarHBondContact N-O 3.36Å; M55-M103 PolarHBondContact O-N 3.22Å; M55-L105 HydrophobicContact SD-CD1 4.13Å
56E79.6Confident81.3Confident113 Ų11372.2 Ų72.253%0.52838%0.38SS..EExtended strand (participates in β ladder)trans-95.2116.5174.4-174.1166.8-155.500108.4S35 F102S35-E56 PolarHBondContact O-N 2.84Å; S35-E56 VanDerWaalsContact O-N 3.12Å; E56-F102 HydrophobicContact CB-CD1 4.16Å; E56-F102 HydrophobicContact CB-CE1 3.96Å; E56-F102 HydrophobicContact CG-CD1 4.22Å; E56-F102 HydrophobicContact CG-CE1 3.65Å; E56-F102 HydrophobicContact CG-CZ 4.29Å
57V70.8Confident80.4Confident7 Ų770.5 Ų70.54%0.04237%0.367CS..  trans-90.8-27.8-178.5-174.30000110A59 L67 R71 S101 M103V57-A59 PolarHBondContact O-N 2.7Å; V57-L67 HydrophobicContact CG1-CD1 3.68Å; V57-L67 WeakPolarHBondContact O-CD1 3.33Å; V57-R71 HydrophobicContact CG1-CG 3.92Å; V57-S101 PolarHBondContact N-O 3.38Å; V57-M103 HydrophobicContact CG2-CE 3.48Å; V57-M103 VanDerWaalsContact CG2-CE 3.48Å; V57-M103 HydrophobicContact CG2-CG 4.25Å
58T64.3Low79.7Confident59 Ų5972.5 Ų72.536%0.36236%0.364SS..  trans-79.198.6172.535.70000111.4S101T58-S101 VanDerWaalsContact CG2-OG 3.26Å; T58-S101 WeakPolarHBondContact CG2-OG 3.38Å; T58-S101 PolarHBondContact N-O 2.84Å; T58-S101 WeakPolarHBondContact OG1-CB 3.46Å; T58-S101 PolarHBondContact OG1-O 3.24Å
59A55.1Low79.1Confident47 Ų4774.2 Ų74.239%0.38837%0.368SS..  trans-100.3123.2156.400000107.8V57 R61 L62V57-A59 PolarHBondContact O-N 2.7Å; A59-R61 HydrophobicContact CB-CB 4.33Å; A59-R61 PolarHBondContact O-N 2.71Å; A59-L62 HydrophobicContact CB-CB 4.44Å; A59-L62 HydrophobicContact CB-CD1 3.84Å; A59-L62 HydrophobicContact CB-CG 3.81Å; A59-L62 PolarHBondContact O-N 3.16Å
60E53.4Low78.3Confident208 Ų20874 Ų7497%0.97237%0.372SS*.THydrogen-bonded Turntrans-58.617.9164-63175.8149.400113
61R56.7Low77.5Confident227 Ų22775.7 Ų75.786%0.85738%0.377SS*.THydrogen-bonded Turntrans-137.8-2.4-166.6-58.7-174.8179.4-166.8-2.6114.4A59A59-R61 HydrophobicContact CB-CB 4.33Å; A59-R61 PolarHBondContact O-N 2.71Å
62L66.8Low77Confident74 Ų7480.4 Ų80.439%0.38740%0.397SS..  trans-110.2143.9-178.3-66.5174.2000111.3A59 Q66A59-L62 HydrophobicContact CB-CB 4.44Å; A59-L62 HydrophobicContact CB-CD1 3.84Å; A59-L62 HydrophobicContact CB-CG 3.81Å; A59-L62 PolarHBondContact O-N 3.16Å; L62-Q66 HydrophobicContact CB-CB 4.11Å; L62-Q66 HydrophobicContact CD2-CB 4.13Å
63S76.7Confident76.4Confident42 Ų4281.9 Ų81.929%0.29441%0.409SS..  trans-67.8159.1171.176.50000110.7E65 Q66 L67S63-E65 PolarHBondContact O-N 2.96Å; S63-Q66 PolarHBondContact O-N 3.36Å; S63-Q66 WeakPolarHBondContact OG-CG 3.36Å; S63-Q66 PolarHBondContact OG-N 3.33Å; S63-Q66 PolarHBondContact OG-OE1 2.92Å; S63-L67 PolarHBondContact O-N 3.12Å
64P79.5Confident76Confident112 Ų11280.7 Ų80.773%0.72741%0.405SS*.Hα-helixtrans-55.7-32.4175.5-2635.1000113.6E68P64-E68 PolarHBondContact O-N 3.42Å
65E81.9Confident75.9Confident152 Ų15283.5 Ų83.571%0.7142%0.418SS*.Hα-helixtrans-69.2-47.9177.9-66.1157.7-175.800111S63 L67 E68 E69S63-E65 PolarHBondContact O-N 2.96Å; E65-L67 VanDerWaalsContact C-N 3.26Å; E65-L67 PolarHBondContact O-N 3.4Å; E65-E68 PolarHBondContact O-N 2.74Å; E65-E68 VanDerWaalsContact O-N 3.17Å; E65-E69 PolarHBondContact O-N 3.31Å
66Q77.7Confident76.1Confident86 Ų8688.4 Ų88.440%0.40244%0.435SS..Hα-helixtrans-62.7-34.3176.2-70.1172.5-37.400112.2L62 S63 E69 V70L62-Q66 HydrophobicContact CB-CB 4.11Å; L62-Q66 HydrophobicContact CD2-CB 4.13Å; S63-Q66 PolarHBondContact O-N 3.36Å; S63-Q66 WeakPolarHBondContact OG-CG 3.36Å; S63-Q66 PolarHBondContact OG-N 3.33Å; S63-Q66 PolarHBondContact OG-OE1 2.92Å; Q66-E69 PolarHBondContact O-N 2.86Å; Q66-V70 WeakPolarHBondContact O-CG2 3.36Å; Q66-V70 PolarHBondContact O-N 3.49Å; Q66-V70 VanDerWaalsContact O-N 3.09Å
67L78.1Confident76.7Confident47 Ų4783.5 Ų83.525%0.24641%0.412CS..Hα-helixtrans-64.7-42176.2-174.363.5000111.6V57 S63 E65 V70 R71V57-L67 HydrophobicContact CG1-CD1 3.68Å; V57-L67 WeakPolarHBondContact O-CD1 3.33Å; S63-L67 PolarHBondContact O-N 3.12Å; E65-L67 VanDerWaalsContact C-N 3.26Å; E65-L67 PolarHBondContact O-N 3.4Å; L67-V70 PolarHBondContact O-N 2.88Å; L67-R71 WeakPolarHBondContact O-CG 3.41Å; L67-R71 PolarHBondContact O-N 3.01Å; L67-R71 VanDerWaalsContact O-N 3.1Å
68E81.8Confident77.6Confident90 Ų9083.2 Ų83.242%0.42141%0.41SS..Hα-helixtrans-66.5-41.7176.8-165.263.8-167.100111.1P64 E65 V70 R71 E72P64-E68 PolarHBondContact O-N 3.42Å; E65-E68 PolarHBondContact O-N 2.74Å; E65-E68 VanDerWaalsContact O-N 3.17Å; E68-V70 VanDerWaalsContact C-N 3.34Å; E68-V70 PolarHBondContact O-N 3.46Å; E68-R71 WeakPolarHBondContact O-CB 3.39Å; E68-R71 PolarHBondContact O-N 3.42Å; E68-R71 VanDerWaalsContact O-N 3.13Å; E68-E72 WeakPolarHBondContact O-CG 3.43Å; E68-E72 PolarHBondContact O-N 2.93Å
69E82.5Confident79.1Confident125 Ų12585 Ų8558%0.58442%0.415SS*.Hα-helixtrans-58.3-43.5175.3-72176.2-18000112.6E65 Q66 R71 E72 A73E65-E69 PolarHBondContact O-N 3.31Å; Q66-E69 PolarHBondContact O-N 2.86Å; E69-R71 VanDerWaalsContact C-N 3.33Å; E69-R71 PolarHBondContact O-N 3Å; E69-E72 PolarHBondContact O-N 3.01Å; E69-A73 VanDerWaalsContact O-CB 3.27Å; E69-A73 WeakPolarHBondContact O-CB 3.24Å; E69-A73 PolarHBondContact O-N 3.29Å
70V80.7Confident81.1Confident57 Ų5782.9 Ų82.935%0.34540%0.397SS..Hα-helixtrans-64.4-39.3176.8170.40000111.3Q66 L67 E68 T74Q66-V70 WeakPolarHBondContact O-CG2 3.36Å; Q66-V70 PolarHBondContact O-N 3.49Å; Q66-V70 VanDerWaalsContact O-N 3.09Å; L67-V70 PolarHBondContact O-N 2.88Å; E68-V70 VanDerWaalsContact C-N 3.34Å; E68-V70 PolarHBondContact O-N 3.46Å; V70-T74 PolarHBondContact O-N 3.36Å; V70-T74 PolarHBondContact O-OG1 2.83Å
71R81Confident83.1Confident66 Ų6673.1 Ų73.125%0.24935%0.351CS..Hα-helixtrans-64.9-49.4176-74.9174.2173.3-162.8-5.5111V57 L67 E68 E69 A73 T74 Q75 P100V57-R71 HydrophobicContact CG1-CG 3.92Å; L67-R71 WeakPolarHBondContact O-CG 3.41Å; L67-R71 PolarHBondContact O-N 3.01Å; L67-R71 VanDerWaalsContact O-N 3.1Å; E68-R71 WeakPolarHBondContact O-CB 3.39Å; E68-R71 PolarHBondContact O-N 3.42Å; E68-R71 VanDerWaalsContact O-N 3.13Å; E69-R71 VanDerWaalsContact C-N 3.33Å; E69-R71 PolarHBondContact O-N 3Å; R71-A73 VanDerWaalsContact C-N 3.34Å; R71-A73 PolarHBondContact O-N 3.44Å; R71-T74 PolarHBondContact O-N 2.79Å; R71-Q75 WeakPolarHBondContact O-CG 3.25Å; R71-Q75 PolarHBondContact O-N 2.67Å; R71-P100 PolarHBondContact NH2-O 3.42Å
72E85.9Confident84.9Confident108 Ų10867.9 Ų67.951%0.50533%0.331SS..Hα-helixtrans-61-42.1177.4-72.6-173.216900112.1E68 E69 T74 Q75 R76E68-E72 WeakPolarHBondContact O-CG 3.43Å; E68-E72 PolarHBondContact O-N 2.93Å; E69-E72 PolarHBondContact O-N 3.01Å; E72-T74 VanDerWaalsContact C-N 3.33Å; E72-T74 PolarHBondContact O-N 2.68Å; E72-Q75 PolarHBondContact O-N 3.07Å; E72-R76 WeakPolarHBondContact O-CB 3.24Å; E72-R76 WeakPolarHBondContact O-CG 3.36Å; E72-R76 PolarHBondContact O-N 3.49Å; E72-R76 PolarHBondContact O-NE 2.78Å
73A84.6Confident86.3Confident31 Ų3168.2 Ų68.226%0.25633%0.331SS..Hα-helixtrans-60.2-43.5175.300000111.7E69 R71 R76 E77E69-A73 VanDerWaalsContact O-CB 3.27Å; E69-A73 WeakPolarHBondContact O-CB 3.24Å; E69-A73 PolarHBondContact O-N 3.29Å; R71-A73 VanDerWaalsContact C-N 3.34Å; R71-A73 PolarHBondContact O-N 3.44Å; A73-R76 PolarHBondContact O-N 2.67Å; A73-E77 PolarHBondContact O-N 3.04Å
74T83.7Confident87.3Confident5 Ų566.3 Ų66.33%0.03132%0.317CS..Hα-helixtrans-72.6-37.5-179.8-46.60000112.2M55 V70 R71 E72 R76 E77 M78 M103M55-T74 HydrophobicContact CE-CG2 4.02Å; M55-T74 HydrophobicContact SD-CG2 4.12Å; V70-T74 PolarHBondContact O-N 3.36Å; V70-T74 PolarHBondContact O-OG1 2.83Å; R71-T74 PolarHBondContact O-N 2.79Å; E72-T74 VanDerWaalsContact C-N 3.33Å; E72-T74 PolarHBondContact O-N 2.68Å; T74-R76 VanDerWaalsContact C-N 3.28Å; T74-R76 PolarHBondContact O-N 2.88Å; T74-E77 WeakPolarHBondContact O-CB 3.38Å; T74-E77 PolarHBondContact O-N 3.38Å; T74-M78 HydrophobicContact CG2-CG 4.36Å; T74-M78 HydrophobicContact CG2-SD 4.23Å; T74-M78 WeakPolarHBondContact O-CB 3.08Å; T74-M78 VanDerWaalsContact O-CG 3.29Å; T74-M78 WeakPolarHBondContact O-CG 3.45Å; T74-M78 PolarHBondContact O-N 3.15Å; T74-M103 VanDerWaalsContact CB-CE 3.43Å; T74-M103 HydrophobicContact CG2-CE 3.21Å; T74-M103 HydrophobicContact CG2-SD 3.48Å; T74-M103 WeakPolarHBondContact CG2-SD 3.46Å; T74-M103 WeakPolarHBondContact OG1-CE 3.34Å
75Q87.2Confident88Confident80 Ų8063.1 Ų63.137%0.37430%0.301SS..Hα-helixtrans-61.4-39173.3-72.7-62.4-19.200111.6R71 E72 M78 H79 E98R71-Q75 WeakPolarHBondContact O-CG 3.25Å; R71-Q75 PolarHBondContact O-N 2.67Å; E72-Q75 PolarHBondContact O-N 3.07Å; Q75-M78 PolarHBondContact O-N 2.95Å; Q75-H79 VanDerWaalsContact O-CB 3.32Å; Q75-H79 WeakPolarHBondContact O-CB 3.29Å; Q75-H79 PolarHBondContact O-N 3.24Å; Q75-E98 PolarHBondContact NE2-OE2 3.25Å
76R90.2Very high88.5Confident121 Ų12159.1 Ų59.146%0.45730%0.3SS..Hα-helixtrans-62.3-47.6172.1-76.4-176-71.6133.9-9.2112E72 A73 T74 M78 H79 I80E72-R76 WeakPolarHBondContact O-CB 3.24Å; E72-R76 WeakPolarHBondContact O-CG 3.36Å; E72-R76 PolarHBondContact O-N 3.49Å; E72-R76 PolarHBondContact O-NE 2.78Å; A73-R76 PolarHBondContact O-N 2.67Å; T74-R76 VanDerWaalsContact C-N 3.28Å; T74-R76 PolarHBondContact O-N 2.88Å; R76-M78 VanDerWaalsContact C-N 3.33Å; R76-M78 PolarHBondContact O-N 3.46Å; R76-H79 PolarHBondContact O-N 2.96Å; R76-I80 WeakPolarHBondContact O-CG1 3.24Å; R76-I80 PolarHBondContact O-N 3.09Å
77E91.3Very high89.4Confident10 Ų1056.4 Ų56.45%0.04729%0.287CS..Hα-helixtrans-55.5-48.3175.6-177.3-177.1175.400110.7K53 A73 T74 I80 L81 F172K53-E77 IonicContact NZ-OE1 3.1Å; K53-E77 PolarHBondContact NZ-OE1 2.8Å; K53-E77 VanDerWaalsContact NZ-OE1 3.16Å; K53-E77 IonicContact NZ-OE2 3.47Å; A73-E77 PolarHBondContact O-N 3.04Å; T74-E77 WeakPolarHBondContact O-CB 3.38Å; T74-E77 PolarHBondContact O-N 3.38Å; E77-I80 PolarHBondContact O-N 3.49Å; E77-L81 HydrophobicContact CG-CD1 3.97Å; E77-L81 WeakPolarHBondContact O-CB 3.3Å; E77-L81 VanDerWaalsContact O-CG 3.31Å; E77-L81 WeakPolarHBondContact O-CG 3.5Å; E77-L81 PolarHBondContact O-N 3.46Å; E77-F172 HydrophobicContact CG-CB 4.07Å
78M91.1Very high90.3Very high0 Ų057.9 Ų57.90%030%0.3CS..Hα-helixtrans-65.4-39.9179.6-69.7178.262.900112.8T74 Q75 R76 L81 R82 S96 E98 M103 L105T74-M78 HydrophobicContact CG2-CG 4.36Å; T74-M78 HydrophobicContact CG2-SD 4.23Å; T74-M78 WeakPolarHBondContact O-CB 3.08Å; T74-M78 VanDerWaalsContact O-CG 3.29Å; T74-M78 WeakPolarHBondContact O-CG 3.45Å; T74-M78 PolarHBondContact O-N 3.15Å; Q75-M78 PolarHBondContact O-N 2.95Å; R76-M78 VanDerWaalsContact C-N 3.33Å; R76-M78 PolarHBondContact O-N 3.46Å; M78-L81 PolarHBondContact O-N 2.71Å; M78-R82 VanDerWaalsContact CE-NH2 3.25Å; M78-R82 VanDerWaalsContact O-CG 3.3Å; M78-R82 WeakPolarHBondContact O-CG 3.44Å; M78-R82 PolarHBondContact O-N 3.19Å; M78-S96 VanDerWaalsContact CE-CB 3.44Å; M78-E98 HydrophobicContact CE-CG 4.01Å; M78-E98 WeakPolarHBondContact CE-OE1 3.17Å; M78-E98 HydrophobicContact SD-CG 4.42Å; M78-M103 HydrophobicContact SD-SD 4.34Å; M78-L105 HydrophobicContact CE-CD2 3.75Å; M78-L105 HydrophobicContact CG-CD1 4.35Å; M78-L105 HydrophobicContact CG-CD2 3.95Å; M78-L105 HydrophobicContact SD-CD2 3.67Å
79H94.7Very high91.1Very high98 Ų9854.6 Ų54.645%0.45428%0.284SS..Hα-helixtrans-61.2-46.8175.9-175.272.2000111.2Q75 R76 R82 Q83 H177Q75-H79 VanDerWaalsContact O-CB 3.32Å; Q75-H79 WeakPolarHBondContact O-CB 3.29Å; Q75-H79 PolarHBondContact O-N 3.24Å; R76-H79 PolarHBondContact O-N 2.96Å; H79-R82 PolarHBondContact O-N 3.32Å; H79-Q83 PolarHBondContact NE2-NE2 2.84Å; H79-Q83 WeakPolarHBondContact O-CG 3.45Å; H79-Q83 PolarHBondContact O-N 3.34Å; H79-Q83 VanDerWaalsContact O-N 3.1Å; H79-H177 AromaticContact CD2-CE1 3.91Å
80I96.6Very high91.9Very high2 Ų248.7 Ų48.71%0.0126%0.257CS..Hα-helixtrans-60.6-49.1175.5-72.9170.9000110.5R76 E77 R82 Q83 V84 I149 F172 S175R76-I80 WeakPolarHBondContact O-CG1 3.24Å; R76-I80 PolarHBondContact O-N 3.09Å; E77-I80 PolarHBondContact O-N 3.49Å; I80-R82 VanDerWaalsContact C-N 3.27Å; I80-R82 PolarHBondContact O-N 3.32Å; I80-Q83 WeakPolarHBondContact O-CB 3.23Å; I80-Q83 PolarHBondContact O-N 2.82Å; I80-V84 HydrophobicContact CG2-CG1 4.36Å; I80-V84 WeakPolarHBondContact O-CG1 3.34Å; I80-V84 WeakPolarHBondContact O-CG2 3.5Å; I80-V84 PolarHBondContact O-N 3.06Å; I80-I149 HydrophobicContact CG2-CD1 4.25Å; I80-I149 HydrophobicContact CG2-CG2 4.1Å; I80-F172 HydrophobicContact CG2-CB 4.28Å; I80-F172 HydrophobicContact CG2-CD1 3.55Å; I80-F172 HydrophobicContact CG2-CE1 4.22Å; I80-F172 HydrophobicContact CG2-CG 4.14Å; I80-S175 WeakPolarHBondContact CD1-O 3.45Å
81L95.9Very high92.7Very high2 Ų246.3 Ų46.31%0.0124%0.242CC..Hα-helixtrans-56.5-39.7178.8-78.5168.4000112.8E77 M78 A85 I91 L93 F107 F172E77-L81 HydrophobicContact CG-CD1 3.97Å; E77-L81 WeakPolarHBondContact O-CB 3.3Å; E77-L81 VanDerWaalsContact O-CG 3.31Å; E77-L81 WeakPolarHBondContact O-CG 3.5Å; E77-L81 PolarHBondContact O-N 3.46Å; M78-L81 PolarHBondContact O-N 2.71Å; L81-A85 PolarHBondContact O-N 2.93Å; L81-I91 HydrophobicContact CD2-CG2 3.99Å; L81-L93 HydrophobicContact CB-CB 4.13Å; L81-L93 HydrophobicContact CB-CD2 4.17Å; L81-F107 HydrophobicContact CD1-CE1 3.84Å; L81-F107 HydrophobicContact CD1-CZ 3.92Å; L81-F107 HydrophobicContact CD2-CE1 4.19Å; L81-F172 HydrophobicContact CD2-CD2 3.55Å; L81-F172 HydrophobicContact CD2-CE2 4.03Å; L81-F172 HydrophobicContact CD2-CG 4.22Å; L81-F172 HydrophobicContact CG-CB 4.47Å; L81-F172 HydrophobicContact CG-CD2 4.32Å
82R95.3Very high93.4Very high117 Ų11744.5 Ų44.544%0.44224%0.239SC..Hα-helixtrans-67.5-37.6175.7-72.3173.7-177.8137.5-2.7112.1M78 H79 I80 A85 L93 S96 E98M78-R82 VanDerWaalsContact CE-NH2 3.25Å; M78-R82 VanDerWaalsContact O-CG 3.3Å; M78-R82 WeakPolarHBondContact O-CG 3.44Å; M78-R82 PolarHBondContact O-N 3.19Å; H79-R82 PolarHBondContact O-N 3.32Å; I80-R82 VanDerWaalsContact C-N 3.27Å; I80-R82 PolarHBondContact O-N 3.32Å; R82-A85 WeakPolarHBondContact O-CB 3.35Å; R82-L93 HydrophobicContact CG-CD2 4.16Å; R82-S96 PolarHBondContact NH2-OG 2.85Å; R82-E98 IonicContact NH2-OE1 3.68Å; R82-E98 PolarHBondContact NH2-OE1 3.35Å
83Q96.3Very high93.9Very high82 Ų8240.4 Ų40.438%0.38322%0.22SC..Hα-helixtrans-68.8-38.8177.6-72-177.8-10.700112.8H79 I80 A85 H177H79-Q83 PolarHBondContact NE2-NE2 2.84Å; H79-Q83 WeakPolarHBondContact O-CG 3.45Å; H79-Q83 PolarHBondContact O-N 3.34Å; H79-Q83 VanDerWaalsContact O-N 3.1Å; I80-Q83 WeakPolarHBondContact O-CB 3.23Å; I80-Q83 PolarHBondContact O-N 2.82Å; Q83-A85 VanDerWaalsContact C-N 3.32Å; Q83-H177 PolarHBondContact OE1-CE1 2.8Å; Q83-H177 PolarHBondContact OE1-NE2 2.74Å
84V97Very high94.4Very high1 Ų141.9 Ų41.91%0.00622%0.223CC..Hα-helixtrans-87.7-4.3-175.9-55.50000113.4I80 G86 H87 I90 F143 L144 I149 F172I80-V84 HydrophobicContact CG2-CG1 4.36Å; I80-V84 WeakPolarHBondContact O-CG1 3.34Å; I80-V84 WeakPolarHBondContact O-CG2 3.5Å; I80-V84 PolarHBondContact O-N 3.06Å; V84-G86 PolarHBondContact O-N 3.39Å; V84-H87 PolarHBondContact O-N 2.74Å; V84-I90 HydrophobicContact CB-CD1 4.1Å; V84-I90 HydrophobicContact CB-CG2 4.29Å; V84-I90 HydrophobicContact CG2-CG2 3.65Å; V84-F143 HydrophobicContact CB-CE1 3.95Å; V84-F143 HydrophobicContact CG1-CE1 4.15Å; V84-L144 HydrophobicContact CB-CD2 4.29Å; V84-L144 HydrophobicContact CG1-CD2 3.49Å; V84-L144 VanDerWaalsContact CG1-CD2 3.49Å; V84-I149 HydrophobicContact CG1-CD1 3.62Å; V84-F172 HydrophobicContact CG2-CZ 4.36Å
85A94.4Very high94.9Very high46 Ų4643.6 Ų43.638%0.3823%0.232SC..THydrogen-bonded Turntrans-56.5135.3178.300000111.3L81 R82 Q83 T92L81-A85 PolarHBondContact O-N 2.93Å; R82-A85 WeakPolarHBondContact O-CB 3.35Å; Q83-A85 VanDerWaalsContact C-N 3.32Å; A85-T92 HydrophobicContact CB-CG2 4.39Å
86G92.7Very high95.2Very high68 Ų6841.4 Ų41.470%0.70123%0.226SC*.THydrogen-bonded Turntrans101.7-14.5-179.300000114.7V84V84-G86 PolarHBondContact O-N 3.39Å
87H97.6Very high95.2Very high28 Ų2836.7 Ų36.713%0.1321%0.208CC..  trans-71.7129.8171.3-169.7-86.1000110.8V84 H89 I90 F143V84-H87 PolarHBondContact O-N 2.74Å; H87-H89 PolarHBondContact ND1-N 3.2Å; H87-H89 VanDerWaalsContact ND1-N 3.18Å; H87-H89 PolarHBondContact O-N 2.95Å; H87-H89 VanDerWaalsContact O-N 3.15Å; H87-I90 HydrophobicContact CB-CB 4.18Å; H87-I90 HydrophobicContact CB-CD1 3.9Å; H87-I90 HydrophobicContact CB-CG1 4.13Å; H87-I90 PolarHBondContact O-N 3.49Å; H87-F143 HydrophobicContact CB-CD1 4.08Å; H87-F143 HydrophobicContact CB-CE1 4.04Å; H87-F143 HydrophobicContact CB-CG 4.5Å; H87-F143 HydrophobicContact CB-CZ 4.43Å; H87-F143 AromaticContact CD2-CD1 3.85Å; H87-F143 AromaticContact CD2-CD2 3.74Å; H87-F143 AromaticContact CD2-CG 3.44Å; H87-F143 VanDerWaalsContact CD2-CG 3.44Å; H87-F143 WeakPolarHBondContact CD2-CG 3.08Å
88P96.9Very high94.9Very high79 Ų7939 Ų3951%0.51322%0.219SC..THydrogen-bonded Turntrans-65.7-22.5-172.125.6-35.9000114.3
89H98.1Very high94.4Very high20 Ų2039.6 Ų39.69%0.09322%0.223CC..THydrogen-bonded Turntrans-107.616.9-178.7-57.1-42.8000113.7H87 S136 E139 A140 I167 R168 L169H87-H89 PolarHBondContact ND1-N 3.2Å; H87-H89 VanDerWaalsContact ND1-N 3.18Å; H87-H89 PolarHBondContact O-N 2.95Å; H87-H89 VanDerWaalsContact O-N 3.15Å; H89-S136 VanDerWaalsContact CD2-CB 3.49Å; H89-S136 WeakPolarHBondContact CD2-CB 3.45Å; H89-S136 PolarHBondContact CE1-OG 2.93Å; H89-S136 PolarHBondContact NE2-OG 2.85Å; H89-S136 VanDerWaalsContact NE2-OG 3.07Å; H89-E139 IonicContact CD2-OE2 2.86Å; H89-E139 PolarHBondContact CD2-OE2 3.43Å; H89-E139 IonicContact NE2-OE2 3.94Å; H89-E139 PolarHBondContact NE2-OE2 3.28Å; H89-A140 HydrophobicContact CB-CB 4.04Å; H89-I167 WeakPolarHBondContact CA-O 3.43Å; H89-I167 PolarHBondContact ND1-O 3.36Å; H89-R168 WeakPolarHBondContact O-CA 3.12Å; H89-L169 PolarHBondContact O-N 3.12Å
90I98.4Very high93.5Very high1 Ų136.6 Ų36.61%0.00521%0.212CC..BIsolated β-bridgetrans-121.8146.9172.6-61.6173.4000108.3V84 H87 A140 F143 L144 R168 L169 F172V84-I90 HydrophobicContact CB-CD1 4.1Å; V84-I90 HydrophobicContact CB-CG2 4.29Å; V84-I90 HydrophobicContact CG2-CG2 3.65Å; H87-I90 HydrophobicContact CB-CB 4.18Å; H87-I90 HydrophobicContact CB-CD1 3.9Å; H87-I90 HydrophobicContact CB-CG1 4.13Å; H87-I90 PolarHBondContact O-N 3.49Å; I90-A140 HydrophobicContact CD1-CB 4.37Å; I90-A140 HydrophobicContact CG1-CB 3.92Å; I90-F143 HydrophobicContact CD1-CD1 3.68Å; I90-F143 HydrophobicContact CD1-CE1 4.14Å; I90-L144 HydrophobicContact CD1-CD2 3.79Å; I90-L144 HydrophobicContact CD1-CG 4.13Å; I90-R168 PolarHBondContact O-NH1 2.7Å; I90-L169 HydrophobicContact CG1-CB 4.49Å; I90-F172 HydrophobicContact CG2-CE2 3.75Å; I90-F172 HydrophobicContact CG2-CZ 3.57Å
91I97.2Very high92.6Very high7 Ų737.3 Ų37.34%0.03622%0.217CC..  trans-66.4133.9177.4-163.669000110.2L81 F107 D108 M110 L160 R168 L169 F172L81-I91 HydrophobicContact CD2-CG2 3.99Å; I91-F107 HydrophobicContact CD1-CB 4.32Å; I91-F107 HydrophobicContact CG1-CB 3.93Å; I91-F107 HydrophobicContact CG1-CD1 3.79Å; I91-F107 HydrophobicContact CG1-CG 4.14Å; I91-F107 HydrophobicContact CG2-CD1 4.22Å; I91-F107 HydrophobicContact CG2-CE1 4.35Å; I91-D108 HydrophobicContact CD1-CB 3.93Å; I91-M110 HydrophobicContact CD1-CG 3.89Å; I91-M110 HydrophobicContact CD1-SD 4.37Å; I91-L160 HydrophobicContact CD1-CD1 4.35Å; I91-R168 HydrophobicContact CB-CB 4.49Å; I91-R168 HydrophobicContact CD1-CB 4.39Å; I91-L169 WeakPolarHBondContact CB-O 3.47Å; I91-L169 WeakPolarHBondContact CG2-O 3.44Å; I91-L169 PolarHBondContact N-O 3.37Å; I91-F172 HydrophobicContact CG2-CE2 4.41Å
92T96.1Very high92Very high29 Ų2940.4 Ų40.418%0.17823%0.23CC..  trans-92.4124.2-179.7-39.50000109.6A85 I94 F107 D108A85-T92 HydrophobicContact CB-CG2 4.39Å; T92-I94 HydrophobicContact CG2-CD1 3.89Å; T92-I94 PolarHBondContact O-N 3.31Å; T92-F107 VanDerWaalsContact O-CA 3.31Å; T92-F107 WeakPolarHBondContact O-CA 3.42Å; T92-F107 WeakPolarHBondContact O-CD1 3.26Å; T92-D108 WeakPolarHBondContact CB-OD2 3.28Å; T92-D108 PolarHBondContact N-OD2 3.27Å; T92-D108 PolarHBondContact OG1-OD2 2.59Å
93L96Very high91.6Very high21 Ų2135.2 Ų35.211%0.1121%0.212CC..EExtended strand (participates in β ladder)trans-75.9108.8164.6-179.567.4000108.4L81 R82 D95 L105 F107L81-L93 HydrophobicContact CB-CB 4.13Å; L81-L93 HydrophobicContact CB-CD2 4.17Å; R82-L93 HydrophobicContact CG-CD2 4.16Å; L93-D95 WeakPolarHBondContact CD1-O 3.46Å; L93-L105 HydrophobicContact CD1-CB 3.88Å; L93-L105 HydrophobicContact CD1-CD2 4.16Å; L93-F107 HydrophobicContact CB-CD1 4.33Å; L93-F107 HydrophobicContact CB-CE1 3.99Å; L93-F107 HydrophobicContact CD1-CD1 4.25Å; L93-F107 HydrophobicContact CD1-CE1 3.72Å; L93-F107 HydrophobicContact CD1-CE2 4.47Å; L93-F107 HydrophobicContact CD1-CZ 3.85Å; L93-F107 HydrophobicContact CG-CE1 4.46Å
94I95.6Very high91.4Very high63 Ų6331.6 Ų31.632%0.32320%0.195SC..EExtended strand (participates in β ladder)trans-82.8-49.3-175.6-55.6-60.2000111.2F50 T92 V106F50-I94 HydrophobicContact CD1-CG1 4.08Å; F50-I94 HydrophobicContact CE1-CG1 4.09Å; F50-I94 HydrophobicContact CE1-CG2 4.14Å; T92-I94 HydrophobicContact CG2-CD1 3.89Å; T92-I94 PolarHBondContact O-N 3.31Å; I94-V106 HydrophobicContact CB-CG1 4.29Å; I94-V106 PolarHBondContact N-O 2.99Å
95D94.4Very high91.2Very high40 Ų4031.6 Ų31.621%0.21419%0.194CC..EExtended strand (participates in β ladder)trans-145.1155.9177.4-79.8-43.5000109.3K23 Y24 L93 Y97 V106K23-D95 WeakPolarHBondContact CE-OD2 3.1Å; K23-D95 IonicContact NZ-OD1 3.75Å; K23-D95 PolarHBondContact NZ-OD1 3.09Å; K23-D95 IonicContact NZ-OD2 3.43Å; K23-D95 PolarHBondContact NZ-OD2 3.26Å; Y24-D95 HydrophobicContact CE2-CB 4.33Å; Y24-D95 VanDerWaalsContact CE2-OD2 3.32Å; Y24-D95 WeakPolarHBondContact CE2-OD2 3.26Å; Y24-D95 VanDerWaalsContact CZ-OD2 3.31Å; Y24-D95 PolarHBondContact OH-OD2 3.43Å; L93-D95 WeakPolarHBondContact CD1-O 3.46Å; D95-Y97 HydrophobicContact CB-CE2 3.94Å; D95-V106 HydrophobicContact CB-CB 4.08Å; D95-V106 HydrophobicContact CB-CG2 4.12Å; D95-V106 PolarHBondContact N-O 3.17Å; D95-V106 PolarHBondContact O-N 3.39Å
96S92.9Very high91.3Very high35 Ų3529.4 Ų29.425%0.24518%0.176CC..EExtended strand (participates in β ladder)trans-137.3136.5172.358.10000110.4M78 R82 F104M78-S96 VanDerWaalsContact CE-CB 3.44Å; R82-S96 PolarHBondContact NH2-OG 2.85Å; S96-F104 CarbonylContact C-O 3.33Å; S96-F104 VanDerWaalsContact CA-O 3.3Å; S96-F104 WeakPolarHBondContact CA-O 3.38Å
97Y91.1Very high91.5Very high21 Ų2127.1 Ų27.18%0.08215%0.147CC..EExtended strand (participates in β ladder)trans-125.2121.6172.8-54.1-88.9000108.9E19 F20 K23 Y24 D95 M103 F104 V106E19-Y97 HydrophobicContact CB-CD1 3.78Å; E19-Y97 HydrophobicContact CB-CE1 3.79Å; F20-Y97 HydrophobicContact CB-CD2 3.83Å; F20-Y97 HydrophobicContact CB-CE2 4.23Å; F20-Y97 HydrophobicContact CB-CG 4.01Å; F20-Y97 AromaticContact CD2-CD2 3.91Å; F20-Y97 HydrophobicContact CD2-CD2 3.91Å; F20-Y97 AromaticContact CD2-CE2 4Å; F20-Y97 HydrophobicContact CD2-CE2 4Å; F20-Y97 HydrophobicContact CG-CD2 4.35Å; K23-Y97 WeakPolarHBondContact CD-OH 3.04Å; Y24-Y97 HydrophobicContact CD2-CE2 4.16Å; Y24-Y97 AromaticContact CE2-CE2 4Å; Y24-Y97 HydrophobicContact CE2-CE2 4Å; D95-Y97 HydrophobicContact CB-CE2 3.94Å; Y97-M103 WeakPolarHBondContact O-CA 3.35Å; Y97-F104 HydrophobicContact CD2-CB 4.21Å; Y97-F104 PolarHBondContact N-O 3.43Å; Y97-F104 PolarHBondContact O-N 2.61Å; Y97-V106 HydrophobicContact CE2-CG2 4.4Å
98E84.6Confident91.4Very high59 Ų5927.5 Ų27.528%0.27615%0.15SC..EExtended strand (participates in β ladder)trans-114134.2-171.9-61.8171.9-139.200109.2A16 Q75 M78 R82 M103A16-E98 WeakPolarHBondContact CB-O 3.32Å; Q75-E98 PolarHBondContact NE2-OE2 3.25Å; M78-E98 HydrophobicContact CE-CG 4.01Å; M78-E98 WeakPolarHBondContact CE-OE1 3.17Å; M78-E98 HydrophobicContact SD-CG 4.42Å; R82-E98 IonicContact NH2-OE1 3.68Å; R82-E98 PolarHBondContact NH2-OE1 3.35Å; E98-M103 HydrophobicContact CG-CG 4.43Å
99S80.6Confident91.3Very high12 Ų1225.1 Ų25.18%0.08413%0.133CC..  trans-140.8161.6170.757.60000110.6D13 S101 F102D13-S99 WeakPolarHBondContact OD1-CB 3.34Å; D13-S99 PolarHBondContact OD1-OG 2.99Å; S99-S101 PolarHBondContact O-N 3.08Å; S99-S101 VanDerWaalsContact O-N 3.09Å; S99-F102 PolarHBondContact N-O 2.86Å; S99-F102 PolarHBondContact O-N 2.69Å; S99-F102 PolarHBondContact OG-N 3.37Å; S99-F102 PolarHBondContact OG-O 3.47Å
100P76.1Confident91.2Very high36 Ų3625 Ų2523%0.23413%0.133CC..SBendtrans-50.2-34.3177.2-31.335.3000115.1L11 D13 R71L11-P100 VanDerWaalsContact O-CD 3.27Å; L11-P100 WeakPolarHBondContact O-CD 3.35Å; D13-P100 WeakPolarHBondContact OD1-CD 3.47Å; R71-P100 PolarHBondContact NH2-O 3.42Å
101S78.3Confident91Very high16 Ų1631.2 Ų31.211%0.11216%0.156CC..SBendtrans-104.9-26.4-174.8-58.50000114.4D13 V57 T58 S99D13-S101 VanDerWaalsContact CG-OG 3.22Å; D13-S101 WeakPolarHBondContact OD1-CB 3.3Å; D13-S101 PolarHBondContact OD1-N 3.1Å; D13-S101 PolarHBondContact OD1-OG 2.73Å; D13-S101 WeakPolarHBondContact OD2-CB 3.32Å; D13-S101 PolarHBondContact OD2-OG 2.68Å; V57-S101 PolarHBondContact N-O 3.38Å; T58-S101 VanDerWaalsContact CG2-OG 3.26Å; T58-S101 WeakPolarHBondContact CG2-OG 3.38Å; T58-S101 PolarHBondContact N-O 2.84Å; T58-S101 WeakPolarHBondContact OG1-CB 3.46Å; T58-S101 PolarHBondContact OG1-O 3.24Å; S99-S101 PolarHBondContact O-N 3.08Å; S99-S101 VanDerWaalsContact O-N 3.09Å
102F83Confident90.8Very high67 Ų6735.1 Ų35.129%0.29417%0.173SC..EExtended strand (participates in β ladder)trans-139.5146.9-176-61.5-82.2000113M55 E56 S99 F104M55-F102 CarbonylContact O-C 3.6Å; M55-F102 VanDerWaalsContact O-CA 3.31Å; M55-F102 WeakPolarHBondContact O-CA 3.09Å; E56-F102 HydrophobicContact CB-CD1 4.16Å; E56-F102 HydrophobicContact CB-CE1 3.96Å; E56-F102 HydrophobicContact CG-CD1 4.22Å; E56-F102 HydrophobicContact CG-CE1 3.65Å; E56-F102 HydrophobicContact CG-CZ 4.29Å; S99-F102 PolarHBondContact N-O 2.86Å; S99-F102 PolarHBondContact O-N 2.69Å; S99-F102 PolarHBondContact OG-N 3.37Å; S99-F102 PolarHBondContact OG-O 3.47Å; F102-F104 HydrophobicContact CB-CD2 4.5Å; F102-F104 HydrophobicContact CB-CE2 3.76Å; F102-F104 HydrophobicContact CB-CZ 4.17Å
103M86.8Confident90.7Very high9 Ų935 Ų354%0.04418%0.177CC..EExtended strand (participates in β ladder)trans-121.4133166.2-69.7179.5-69.200110.5I54 M55 V57 T74 M78 Y97 E98I54-M103 CarbonylContact C-O 3.51Å; I54-M103 WeakPolarHBondContact CA-O 3.33Å; M55-M103 HydrophobicContact CB-CB 4.35Å; M55-M103 HydrophobicContact CB-CE 4.44Å; M55-M103 HydrophobicContact CE-CE 4.36Å; M55-M103 PolarHBondContact N-O 3.36Å; M55-M103 PolarHBondContact O-N 3.22Å; V57-M103 HydrophobicContact CG2-CE 3.48Å; V57-M103 VanDerWaalsContact CG2-CE 3.48Å; V57-M103 HydrophobicContact CG2-CG 4.25Å; T74-M103 VanDerWaalsContact CB-CE 3.43Å; T74-M103 HydrophobicContact CG2-CE 3.21Å; T74-M103 HydrophobicContact CG2-SD 3.48Å; T74-M103 WeakPolarHBondContact CG2-SD 3.46Å; T74-M103 WeakPolarHBondContact OG1-CE 3.34Å; M78-M103 HydrophobicContact SD-SD 4.34Å; Y97-M103 WeakPolarHBondContact O-CA 3.35Å; E98-M103 HydrophobicContact CG-CG 4.43Å
104F91.6Very high90.7Very high6 Ų635.9 Ų35.93%0.02618%0.181CC..EExtended strand (participates in β ladder)trans-113.8111.9176.2-56.3-100.3000108.5A17 F20 V52 I54 S96 Y97 F102A17-F104 HydrophobicContact CB-CE2 4.42Å; A17-F104 HydrophobicContact CB-CZ 4.38Å; F20-F104 HydrophobicContact CB-CD1 4.37Å; F20-F104 HydrophobicContact CB-CG 4.25Å; F20-F104 AromaticContact CD1-CD1 3.67Å; F20-F104 HydrophobicContact CD1-CD1 3.67Å; F20-F104 AromaticContact CD1-CE1 3.85Å; F20-F104 HydrophobicContact CD1-CE1 3.85Å; F20-F104 HydrophobicContact CD1-CG 4.36Å; F20-F104 HydrophobicContact CD2-CB 4.07Å; F20-F104 HydrophobicContact CD2-CD1 4.17Å; F20-F104 HydrophobicContact CD2-CG 4.31Å; F20-F104 HydrophobicContact CE1-CD1 4.01Å; F20-F104 HydrophobicContact CE1-CE1 4.25Å; F20-F104 HydrophobicContact CE2-CD1 4.48Å; F20-F104 HydrophobicContact CG-CB 4.25Å; F20-F104 AromaticContact CG-CD1 3.77Å; F20-F104 HydrophobicContact CG-CD1 3.77Å; F20-F104 HydrophobicContact CG-CE1 4.32Å; F20-F104 HydrophobicContact CG-CG 4.01Å; F20-F104 HydrophobicContact CZ-CD1 4.42Å; V52-F104 HydrophobicContact CG2-CB 4.08Å; V52-F104 HydrophobicContact CG2-CD1 4.32Å; I54-F104 HydrophobicContact CB-CD1 4.44Å; I54-F104 HydrophobicContact CD1-CD1 4.27Å; I54-F104 HydrophobicContact CD1-CE1 4.15Å; I54-F104 HydrophobicContact CG1-CD1 3.85Å; I54-F104 HydrophobicContact CG1-CE1 4.12Å; I54-F104 HydrophobicContact CG2-CD1 4.04Å; I54-F104 HydrophobicContact CG2-CE1 3.77Å; I54-F104 HydrophobicContact CG2-CZ 4.32Å; S96-F104 CarbonylContact C-O 3.33Å; S96-F104 VanDerWaalsContact CA-O 3.3Å; S96-F104 WeakPolarHBondContact CA-O 3.38Å; Y97-F104 HydrophobicContact CD2-CB 4.21Å; Y97-F104 PolarHBondContact N-O 3.43Å; Y97-F104 PolarHBondContact O-N 2.61Å; F102-F104 HydrophobicContact CB-CD2 4.5Å; F102-F104 HydrophobicContact CB-CE2 3.76Å; F102-F104 HydrophobicContact CB-CZ 4.17Å
105L92.9Very high90.7Very high0 Ų032.9 Ų32.90%017%0.165CC..EExtended strand (participates in β ladder)trans-110.3115.4178.5-55.1179.9000109V52 K53 M55 M78 L93 F107V52-L105 CarbonylContact C-O 3.56Å; V52-L105 VanDerWaalsContact CA-O 3.3Å; V52-L105 WeakPolarHBondContact CA-O 3.37Å; K53-L105 HydrophobicContact CB-CB 4.38Å; K53-L105 PolarHBondContact N-O 3.28Å; K53-L105 PolarHBondContact O-N 3.49Å; M55-L105 HydrophobicContact SD-CD1 4.13Å; M78-L105 HydrophobicContact CE-CD2 3.75Å; M78-L105 HydrophobicContact CG-CD1 4.35Å; M78-L105 HydrophobicContact CG-CD2 3.95Å; M78-L105 HydrophobicContact SD-CD2 3.67Å; L93-L105 HydrophobicContact CD1-CB 3.88Å; L93-L105 HydrophobicContact CD1-CD2 4.16Å; L105-F107 HydrophobicContact CB-CD2 4.27Å; L105-F107 HydrophobicContact CB-CE2 3.38Å; L105-F107 HydrophobicContact CB-CZ 3.69Å; L105-F107 HydrophobicContact CD1-CE2 4.41Å; L105-F107 HydrophobicContact CD1-CZ 4.18Å; L105-F107 WeakPolarHBondContact O-CD2 3.39Å; L105-F107 WeakPolarHBondContact O-CE2 3.42Å
106V96.4Very high90.6Very high0 Ų032 Ų320%016%0.159CC..EExtended strand (participates in β ladder)trans-96.4128.2-177.9-174.20000109.5F20 Y24 F50 A51 V52 I94 D95 Y97F20-V106 HydrophobicContact CD2-CG2 4.39Å; F20-V106 HydrophobicContact CE2-CG2 4.15Å; Y24-V106 HydrophobicContact CD2-CG2 4.26Å; Y24-V106 HydrophobicContact CE1-CG1 4.02Å; Y24-V106 HydrophobicContact CE2-CG1 4.48Å; Y24-V106 HydrophobicContact CE2-CG2 3.98Å; F50-V106 HydrophobicContact CB-CG1 3.68Å; F50-V106 HydrophobicContact CD1-CG1 4.34Å; F50-V106 HydrophobicContact CG-CG1 4.01Å; A51-V106 CarbonylContact O-C 3.58Å; A51-V106 WeakPolarHBondContact O-CA 3.45Å; V52-V106 HydrophobicContact CG2-CG2 4.3Å; I94-V106 HydrophobicContact CB-CG1 4.29Å; I94-V106 PolarHBondContact N-O 2.99Å; D95-V106 HydrophobicContact CB-CB 4.08Å; D95-V106 HydrophobicContact CB-CG2 4.12Å; D95-V106 PolarHBondContact N-O 3.17Å; D95-V106 PolarHBondContact O-N 3.39Å; Y97-V106 HydrophobicContact CE2-CG2 4.4Å
107F96.7Very high90.5Very high21 Ų2132.7 Ų32.79%0.09216%0.161CC..EExtended strand (participates in β ladder)trans-129.6165.4-174.9-61.5-81.3000112.2F50 A51 K53 L81 I91 T92 L93 L105 L109F50-F107 WeakPolarHBondContact CB-O 3.39Å; A51-F107 PolarHBondContact N-O 3.46Å; A51-F107 PolarHBondContact O-N 2.88Å; K53-F107 HydrophobicContact CB-CD2 4.44Å; K53-F107 HydrophobicContact CB-CE2 3.95Å; K53-F107 HydrophobicContact CD-CE2 4.49Å; L81-F107 HydrophobicContact CD1-CE1 3.84Å; L81-F107 HydrophobicContact CD1-CZ 3.92Å; L81-F107 HydrophobicContact CD2-CE1 4.19Å; I91-F107 HydrophobicContact CD1-CB 4.32Å; I91-F107 HydrophobicContact CG1-CB 3.93Å; I91-F107 HydrophobicContact CG1-CD1 3.79Å; I91-F107 HydrophobicContact CG1-CG 4.14Å; I91-F107 HydrophobicContact CG2-CD1 4.22Å; I91-F107 HydrophobicContact CG2-CE1 4.35Å; T92-F107 VanDerWaalsContact O-CA 3.31Å; T92-F107 WeakPolarHBondContact O-CA 3.42Å; T92-F107 WeakPolarHBondContact O-CD1 3.26Å; L93-F107 HydrophobicContact CB-CD1 4.33Å; L93-F107 HydrophobicContact CB-CE1 3.99Å; L93-F107 HydrophobicContact CD1-CD1 4.25Å; L93-F107 HydrophobicContact CD1-CE1 3.72Å; L93-F107 HydrophobicContact CD1-CE2 4.47Å; L93-F107 HydrophobicContact CD1-CZ 3.85Å; L93-F107 HydrophobicContact CG-CE1 4.46Å; L105-F107 HydrophobicContact CB-CD2 4.27Å; L105-F107 HydrophobicContact CB-CE2 3.38Å; L105-F107 HydrophobicContact CB-CZ 3.69Å; L105-F107 HydrophobicContact CD1-CE2 4.41Å; L105-F107 HydrophobicContact CD1-CZ 4.18Å; L105-F107 WeakPolarHBondContact O-CD2 3.39Å; L105-F107 WeakPolarHBondContact O-CE2 3.42Å; F107-L109 PolarHBondContact O-N 2.95Å
108D94.8Very high90.6Very high36 Ų3633 Ų3319%0.19316%0.162CC..EExtended strand (participates in β ladder)trans-51.9136165.4-63.6-49.2000111.3I91 T92 M110 R168I91-D108 HydrophobicContact CD1-CB 3.93Å; T92-D108 WeakPolarHBondContact CB-OD2 3.28Å; T92-D108 PolarHBondContact N-OD2 3.27Å; T92-D108 PolarHBondContact OG1-OD2 2.59Å; D108-M110 PolarHBondContact O-N 2.65Å; D108-R168 IonicContact OD2-CZ 2.82Å; D108-R168 IonicContact OD2-NE 3.84Å; D108-R168 IonicContact OD2-NH1 2.86Å; D108-R168 PolarHBondContact OD2-NH1 2.87Å; D108-R168 IonicContact OD2-NH2 3.33Å
109L96Very high90.9Very high29 Ų2930.3 Ų30.315%0.15215%0.149CC..  trans-81.3112.7176.2-179.563000111.5I30 R40 E49 A51 F107 R111I30-L109 HydrophobicContact CD1-CD1 3.93Å; R40-L109 HydrophobicContact CG-CD1 4.41Å; R40-L109 HydrophobicContact CG-CD2 4.02Å; E49-L109 HydrophobicContact CB-CD2 3.79Å; A51-L109 HydrophobicContact CB-CD1 4.19Å; F107-L109 PolarHBondContact O-N 2.95Å; L109-R111 HydrophobicContact CD2-CG 4.22Å; L109-R111 HydrophobicContact CG-CG 4.14Å; L109-R111 PolarHBondContact O-N 2.86Å
110M96.3Very high91.1Very high18 Ų1830 Ų309%0.08915%0.147CC..  trans-95.388178.2-57.6-58.7-73.600111.1I91 D108 K112 G113 L160 L161 D162 R168I91-M110 HydrophobicContact CD1-CG 3.89Å; I91-M110 HydrophobicContact CD1-SD 4.37Å; D108-M110 PolarHBondContact O-N 2.65Å; M110-K112 VanDerWaalsContact C-N 3.29Å; M110-K112 PolarHBondContact O-N 2.82Å; M110-G113 PolarHBondContact O-N 3.13Å; M110-L160 HydrophobicContact CB-CB 3.63Å; M110-L160 HydrophobicContact CB-CD1 4.1Å; M110-L160 HydrophobicContact CB-CG 4.41Å; M110-L160 HydrophobicContact CE-CB 4.04Å; M110-L160 WeakPolarHBondContact CE-O 3.34Å; M110-L160 HydrophobicContact CG-CB 3.59Å; M110-L160 HydrophobicContact CG-CD1 3.8Å; M110-L160 HydrophobicContact CG-CG 4.35Å; M110-L161 CarbonylContact C-O 3.56Å; M110-L161 VanDerWaalsContact CE-C 3.5Å; M110-D162 HydrophobicContact CE-CB 3.91Å; M110-D162 HydrophobicContact SD-CB 4.31Å; M110-R168 HydrophobicContact CE-CB 3.74Å; M110-R168 HydrophobicContact CE-CG 3.58Å; M110-R168 HydrophobicContact SD-CB 4.3Å; M110-R168 VanDerWaalsContact SD-CD 3.54Å; M110-R168 HydrophobicContact SD-CG 4Å
111R93.7Very high91.6Very high131 Ų13133.7 Ų33.749%0.49416%0.161SC..THydrogen-bonded Turntrans-63.9-25.4-167.3-62.5-169.7-166.9-89.3-4.1115.7E49 L109 G113 D163E49-R111 IonicContact OE2-CZ 3.66Å; E49-R111 IonicContact OE2-NH1 3.3Å; E49-R111 PolarHBondContact OE2-NH1 3.04Å; E49-R111 IonicContact OE2-NH2 3.18Å; E49-R111 PolarHBondContact OE2-NH2 3.41Å; L109-R111 HydrophobicContact CD2-CG 4.22Å; L109-R111 HydrophobicContact CG-CG 4.14Å; L109-R111 PolarHBondContact O-N 2.86Å; R111-G113 VanDerWaalsContact C-N 3.26Å; R111-D163 VanDerWaalsContact CD-OD2 3.24Å; R111-D163 WeakPolarHBondContact CD-OD2 3.2Å; R111-D163 IonicContact NE-OD2 2.67Å; R111-D163 PolarHBondContact NE-OD2 3.44Å
112K94Very high92Very high88 Ų8837.2 Ų37.238%0.38317%0.174SC..THydrogen-bonded Turntrans-87.62.7176.3-68.4-164.8-178168.80113.2M110 L161 D162 D163 M165M110-K112 VanDerWaalsContact C-N 3.29Å; M110-K112 PolarHBondContact O-N 2.82Å; K112-L161 WeakPolarHBondContact CA-O 3.36Å; K112-L161 HydrophobicContact CB-CB 3.68Å; K112-L161 WeakPolarHBondContact CB-O 3.46Å; K112-L161 PolarHBondContact N-O 2.73Å; K112-D162 VanDerWaalsContact CD-O 3.3Å; K112-D162 WeakPolarHBondContact CD-O 3.48Å; K112-D162 WeakPolarHBondContact CG-O 3.4Å; K112-D163 WeakPolarHBondContact CE-O 3.21Å; K112-D163 PolarHBondContact NZ-O 3.23Å; K112-M165 HydrophobicContact CD-SD 3.5Å; K112-M165 WeakPolarHBondContact CD-SD 3.42Å; K112-M165 PolarHBondContact NZ-SD 2.99Å
113G93.7Very high92.2Very high26 Ų2634.9 Ų34.927%0.26817%0.165SC..EExtended strand (participates in β ladder)trans66-145.4173.900000112.3M110 R111 L160 L161M110-G113 PolarHBondContact O-N 3.13Å; R111-G113 VanDerWaalsContact C-N 3.26Å; G113-L160 CarbonylContact O-C 3.56Å; G113-L160 VanDerWaalsContact O-CA 3.32Å; G113-L160 WeakPolarHBondContact O-CA 3.42Å; G113-L161 PolarHBondContact O-N 3.08Å
114E94.8Very high92.3Very high41 Ų4135.2 Ų35.219%0.19217%0.17CC..EExtended strand (participates in β ladder)trans-77.7142.7-173.8-57.4164.7-141.300112F116 D117 Y118 L160 K364E114-F116 HydrophobicContact CB-CB 4.35Å; E114-F116 PolarHBondContact O-N 3Å; E114-D117 PolarHBondContact O-N 2.73Å; E114-D117 VanDerWaalsContact O-N 3.15Å; E114-Y118 PolarHBondContact O-N 2.98Å; E114-Y118 VanDerWaalsContact O-N 3.14Å; E114-L160 HydrophobicContact CG-CD2 4.12Å; E114-K364 IonicContact OE1-NZ 3.44Å; E114-K364 PolarHBondContact OE1-NZ 3.29Å; E114-K364 VanDerWaalsContact OE1-NZ 3.1Å; E114-K364 IonicContact OE2-NZ 2.68Å
115L96.4Very high92.4Very high0 Ų035.1 Ų35.10%017%0.169CC..Hα-helixtrans-61.2-29.1171.4175.362.5000111.3Y118 L119 I133 P156 I159 L161 L226L115-Y118 HydrophobicContact CD1-CD1 4.14Å; L115-Y118 PolarHBondContact O-N 3.22Å; L115-L119 WeakPolarHBondContact O-CB 3.47Å; L115-L119 PolarHBondContact O-N 3.18Å; L115-I133 HydrophobicContact CD1-CD1 3.92Å; L115-I133 HydrophobicContact CD2-CG2 3.84Å; L115-P156 HydrophobicContact CB-CB 4.49Å; L115-P156 WeakPolarHBondContact CB-O 3.45Å; L115-P156 HydrophobicContact CG-CB 4.39Å; L115-P156 PolarHBondContact N-O 3.33Å; L115-I159 HydrophobicContact CB-CB 4Å; L115-I159 HydrophobicContact CB-CG2 4.1Å; L115-I159 VanDerWaalsContact CB-O 3.25Å; L115-I159 WeakPolarHBondContact CB-O 3.29Å; L115-I159 HydrophobicContact CD2-CB 4.03Å; L115-I159 HydrophobicContact CD2-CD1 4Å; L115-I159 HydrophobicContact CD2-CG2 3.83Å; L115-I159 PolarHBondContact N-O 3.46Å; L115-L161 HydrophobicContact CB-CD1 4.36Å; L115-L161 HydrophobicContact CD1-CD1 4.03Å; L115-L226 HydrophobicContact CD1-CD2 4.08Å; L115-L226 HydrophobicContact CD2-CD1 4.44Å; L115-L226 HydrophobicContact CD2-CD2 3.97Å; L115-L226 HydrophobicContact CG-CD2 4.06Å
116F92.8Very high92.5Very high20 Ų2037.4 Ų37.49%0.08819%0.186CC..Hα-helixtrans-57.4-51171.4-177.1-93.2000112.3E114 Y118 L119 T120 P156 E157 R370E114-F116 HydrophobicContact CB-CB 4.35Å; E114-F116 PolarHBondContact O-N 3Å; F116-Y118 VanDerWaalsContact C-N 3.34Å; F116-Y118 PolarHBondContact O-N 2.82Å; F116-L119 PolarHBondContact O-N 3.15Å; F116-T120 WeakPolarHBondContact O-CB 3.32Å; F116-T120 PolarHBondContact O-N 2.7Å; F116-T120 PolarHBondContact O-OG1 3.26Å; F116-P156 HydrophobicContact CB-CB 3.98Å; F116-P156 HydrophobicContact CD2-CB 4.47Å; F116-P156 PolarHBondContact N-O 2.78Å; F116-P156 VanDerWaalsContact N-O 3.1Å; F116-E157 HydrophobicContact CB-CG 3.91Å; F116-E157 HydrophobicContact CD2-CG 4.16Å; F116-E157 HydrophobicContact CG-CG 4Å; F116-R370 HydrophobicContact CE2-CB 4.38Å; F116-R370 HydrophobicContact CZ-CB 4.41Å
117D89.3Confident92.4Very high51 Ų5139 Ų3927%0.27319%0.193SC..Hα-helixtrans-64.2-41.7179.5-74.7-26.3000110.5E114 T120 E121 K364E114-D117 PolarHBondContact O-N 2.73Å; E114-D117 VanDerWaalsContact O-N 3.15Å; D117-T120 WeakPolarHBondContact O-CA 3.45Å; D117-T120 WeakPolarHBondContact O-CB 3.48Å; D117-T120 PolarHBondContact O-N 2.97Å; D117-T120 VanDerWaalsContact O-N 3.09Å; D117-E121 PolarHBondContact O-N 2.73Å; D117-K364 IonicContact OD1-NZ 2.69Å; D117-K364 IonicContact OD2-NZ 3.59Å; D117-K364 PolarHBondContact OD2-NZ 2.95Å
118Y93.4Very high92.3Very high28 Ų2845.9 Ų45.911%0.1122%0.223CC..Hα-helixtrans-60.8-46.4175.2-178.8-106.4000112.9E114 L115 F116 T120 E121 K122 L125 E129 L161 M165E114-Y118 PolarHBondContact O-N 2.98Å; E114-Y118 VanDerWaalsContact O-N 3.14Å; L115-Y118 HydrophobicContact CD1-CD1 4.14Å; L115-Y118 PolarHBondContact O-N 3.22Å; F116-Y118 VanDerWaalsContact C-N 3.34Å; F116-Y118 PolarHBondContact O-N 2.82Å; Y118-T120 PolarHBondContact O-N 3.31Å; Y118-E121 PolarHBondContact O-N 3.05Å; Y118-K122 HydrophobicContact CD2-CG 4.43Å; Y118-K122 HydrophobicContact CE1-CG 4.08Å; Y118-K122 HydrophobicContact CE2-CD 4.45Å; Y118-K122 HydrophobicContact CE2-CG 3.98Å; Y118-K122 WeakPolarHBondContact O-CG 3.45Å; Y118-K122 PolarHBondContact O-N 2.76Å; Y118-K122 WeakPolarHBondContact OH-CE 3.46Å; Y118-L125 HydrophobicContact CD1-CD1 4.48Å; Y118-L125 HydrophobicContact CD1-CD2 4.1Å; Y118-L125 HydrophobicContact CE1-CD1 4.22Å; Y118-L125 HydrophobicContact CE1-CD2 3.58Å; Y118-E129 PolarHBondContact OH-OE1 2.91Å; Y118-L161 HydrophobicContact CD1-CD1 3.99Å; Y118-L161 HydrophobicContact CD2-CD1 4.4Å; Y118-L161 HydrophobicContact CG-CD1 3.71Å; Y118-M165 HydrophobicContact CD1-CE 3.9Å; Y118-M165 HydrophobicContact CD2-CE 3.99Å; Y118-M165 HydrophobicContact CE1-CE 3.42Å; Y118-M165 VanDerWaalsContact CE1-CE 3.42Å; Y118-M165 HydrophobicContact CE2-CE 3.52Å; Y118-M165 HydrophobicContact CE2-SD 4.1Å; Y118-M165 HydrophobicContact CG-CE 4.16Å
119L91.8Very high92.3Very high2 Ų247.8 Ų47.81%0.0123%0.231CC..Hα-helixtrans-61-35.1174.3178.165000110.9L115 F116 K122 V123 L125 T225 L226 R370L115-L119 WeakPolarHBondContact O-CB 3.47Å; L115-L119 PolarHBondContact O-N 3.18Å; F116-L119 PolarHBondContact O-N 3.15Å; L119-K122 PolarHBondContact O-N 3.14Å; L119-V123 CarbonylContact O-C 2.71Å; L119-V123 WeakPolarHBondContact O-CA 3.27Å; L119-V123 PolarHBondContact O-N 2.88Å; L119-L125 HydrophobicContact CD1-CD2 4.44Å; L119-L125 HydrophobicContact CD1-CG 4.05Å; L119-T225 HydrophobicContact CD2-CG2 3.78Å; L119-L226 HydrophobicContact CD1-CD2 4.37Å; L119-L226 HydrophobicContact CD2-CD2 4.29Å; L119-R370 PolarHBondContact O-NH2 3.27Å
120T85Confident92.4Very high4 Ų446.4 Ų46.43%0.02522%0.223CC..Hα-helixtrans-66.9-41.8178.2-50.10000113.3F116 D117 Y118 K122 F355 R370F116-T120 WeakPolarHBondContact O-CB 3.32Å; F116-T120 PolarHBondContact O-N 2.7Å; F116-T120 PolarHBondContact O-OG1 3.26Å; D117-T120 WeakPolarHBondContact O-CA 3.45Å; D117-T120 WeakPolarHBondContact O-CB 3.48Å; D117-T120 PolarHBondContact O-N 2.97Å; D117-T120 VanDerWaalsContact O-N 3.09Å; Y118-T120 PolarHBondContact O-N 3.31Å; T120-K122 VanDerWaalsContact C-N 3.33Å; T120-K122 PolarHBondContact O-N 3.47Å; T120-F355 HydrophobicContact CG2-CB 4.43Å; T120-F355 HydrophobicContact CG2-CD1 3.69Å; T120-F355 HydrophobicContact CG2-CD2 3.26Å; T120-F355 HydrophobicContact CG2-CE1 3.6Å; T120-F355 HydrophobicContact CG2-CE2 3.2Å; T120-F355 HydrophobicContact CG2-CG 3.51Å; T120-F355 HydrophobicContact CG2-CZ 3.36Å; T120-R370 VanDerWaalsContact CB-NH1 3.34Å; T120-R370 PolarHBondContact OG1-NH1 3.14Å
121E87Confident92.5Very high115 Ų11548.6 Ų48.654%0.53723%0.231SC..Hα-helixtrans-65.5-34.2172.2-162.6-158.5141.700113.2D117 Y118 N352D117-E121 PolarHBondContact O-N 2.73Å; Y118-E121 PolarHBondContact O-N 3.05Å; E121-N352 PolarHBondContact O-ND2 3.46Å; E121-N352 PolarHBondContact O-OD1 2.86Å
122K86.4Confident92.6Very high89 Ų8944.9 Ų44.939%0.38723%0.225SC..Hα-helixtrans-90.1-12.7-176.5-64.8-63.8-179.6-173.30114.5Y118 L119 T120 A124 L125Y118-K122 HydrophobicContact CD2-CG 4.43Å; Y118-K122 HydrophobicContact CE1-CG 4.08Å; Y118-K122 HydrophobicContact CE2-CD 4.45Å; Y118-K122 HydrophobicContact CE2-CG 3.98Å; Y118-K122 WeakPolarHBondContact O-CG 3.45Å; Y118-K122 PolarHBondContact O-N 2.76Å; Y118-K122 WeakPolarHBondContact OH-CE 3.46Å; L119-K122 PolarHBondContact O-N 3.14Å; T120-K122 VanDerWaalsContact C-N 3.33Å; T120-K122 PolarHBondContact O-N 3.47Å; K122-A124 PolarHBondContact O-N 3.44Å; K122-L125 HydrophobicContact CB-CD2 3.74Å; K122-L125 HydrophobicContact CG-CD2 4Å
123V86Confident92.8Very high18 Ų1841.1 Ų41.111%0.10921%0.209CC..SBendtrans66.2-53.2-169.3-1740000113.6L119 G229 D351 N352 R370L119-V123 CarbonylContact O-C 2.71Å; L119-V123 WeakPolarHBondContact O-CA 3.27Å; L119-V123 PolarHBondContact O-N 2.88Å; V123-G229 WeakPolarHBondContact O-CA 3.42Å; V123-D351 HydrophobicContact CG2-CB 4.07Å; V123-N352 VanDerWaalsContact CG2-OD1 3.29Å; V123-N352 WeakPolarHBondContact CG2-OD1 3.38Å; V123-R370 PolarHBondContact O-NH2 3.36Å
124A89.9Confident93Very high17 Ų1739.9 Ų39.914%0.1420%0.196CC..SBendtrans-156.3146.7176.400000110.1K122K122-A124 PolarHBondContact O-N 3.44Å
125L93.7Very high93.2Very high3 Ų341.1 Ų41.12%0.01620%0.199CC..  trans-91158.7-176.3-56-171.2000113Y118 L119 K122 E129 I133 L226 R260Y118-L125 HydrophobicContact CD1-CD1 4.48Å; Y118-L125 HydrophobicContact CD1-CD2 4.1Å; Y118-L125 HydrophobicContact CE1-CD1 4.22Å; Y118-L125 HydrophobicContact CE1-CD2 3.58Å; L119-L125 HydrophobicContact CD1-CD2 4.44Å; L119-L125 HydrophobicContact CD1-CG 4.05Å; K122-L125 HydrophobicContact CB-CD2 3.74Å; K122-L125 HydrophobicContact CG-CD2 4Å; L125-E129 HydrophobicContact CB-CB 4.47Å; L125-I133 HydrophobicContact CD1-CD1 3.63Å; L125-L226 HydrophobicContact CD1-CB 4.41Å; L125-L226 HydrophobicContact CD1-CD2 3.88Å; L125-L226 PolarHBondContact N-O 3.15Å; L125-R260 VanDerWaalsContact O-CZ 3.3Å; L125-R260 PolarHBondContact O-NH1 3.27Å; L125-R260 PolarHBondContact O-NH2 3.15Å
126S94.3Very high93.3Very high49 Ų4941.6 Ų41.634%0.34320%0.202SC..  trans-73.5153.5169.767.70000110.9K128 E129 T130S126-K128 PolarHBondContact O-N 3.17Å; S126-K128 VanDerWaalsContact O-N 3.15Å; S126-E129 WeakPolarHBondContact CB-OE2 3.26Å; S126-E129 PolarHBondContact N-OE2 3.49Å; S126-E129 PolarHBondContact O-N 2.79Å; S126-E129 WeakPolarHBondContact OG-CG 3.48Å; S126-E129 PolarHBondContact OG-N 2.85Å; S126-E129 PolarHBondContact OG-OE2 2.88Å; S126-T130 WeakPolarHBondContact O-CB 3.48Å; S126-T130 PolarHBondContact O-N 2.78Å; S126-T130 PolarHBondContact O-OG1 2.72Å; S126-T130 VanDerWaalsContact O-OG1 3.05Å
127E95.3Very high93.6Very high33 Ų3340.6 Ų40.615%0.15420%0.198CC..Hα-helixtrans-58.9-29.1175.1-77-176.8-141.600112.5R131 L227 R260 S261 V264 F290E127-R131 WeakPolarHBondContact O-CB 3.28Å; E127-R131 PolarHBondContact O-N 3.35Å; E127-L227 HydrophobicContact CG-CD2 3.85Å; E127-R260 VanDerWaalsContact OE1-CA 3.26Å; E127-R260 WeakPolarHBondContact OE1-CA 3.41Å; E127-S261 PolarHBondContact OE1-N 3.1Å; E127-S261 PolarHBondContact OE1-OG 2.89Å; E127-S261 WeakPolarHBondContact OE2-CB 3.36Å; E127-S261 PolarHBondContact OE2-OG 3.46Å; E127-V264 HydrophobicContact CG-CG1 4.42Å; E127-F290 HydrophobicContact CB-CE2 4.47Å
128K94.3Very high94Very high165 Ų16538.2 Ų38.272%0.71719%0.185SC*.Hα-helixtrans-65.4-49176.6-176.3-177.1175.9-175.40111.6S126 S132S126-K128 PolarHBondContact O-N 3.17Å; S126-K128 VanDerWaalsContact O-N 3.15Å; K128-S132 PolarHBondContact O-N 3.3Å
129E95.1Very high94.3Very high76 Ų7640 Ų4036%0.35519%0.194SC..Hα-helixtrans-67.1-47177.8-70163.8130.700110.8Y118 L125 S126 R131 S132 I133Y118-E129 PolarHBondContact OH-OE1 2.91Å; L125-E129 HydrophobicContact CB-CB 4.47Å; S126-E129 WeakPolarHBondContact CB-OE2 3.26Å; S126-E129 PolarHBondContact N-OE2 3.49Å; S126-E129 PolarHBondContact O-N 2.79Å; S126-E129 WeakPolarHBondContact OG-CG 3.48Å; S126-E129 PolarHBondContact OG-N 2.85Å; S126-E129 PolarHBondContact OG-OE2 2.88Å; E129-R131 VanDerWaalsContact C-N 3.28Å; E129-R131 PolarHBondContact O-N 3.42Å; E129-S132 WeakPolarHBondContact O-CB 3.33Å; E129-S132 PolarHBondContact O-N 2.88Å; E129-I133 PolarHBondContact O-N 2.8Å
130T97.4Very high94.6Very high0 Ų040 Ų400%019%0.194CC..Hα-helixtrans-56.8-41.8176.5-58.40000111.7S126 S132 I133 M134 L223 L226 L227S126-T130 WeakPolarHBondContact O-CB 3.48Å; S126-T130 PolarHBondContact O-N 2.78Å; S126-T130 PolarHBondContact O-OG1 2.72Å; S126-T130 VanDerWaalsContact O-OG1 3.05Å; T130-S132 VanDerWaalsContact C-N 3.31Å; T130-S132 PolarHBondContact O-N 3.23Å; T130-I133 PolarHBondContact O-N 3.12Å; T130-M134 HydrophobicContact CG2-CG 3.9Å; T130-M134 VanDerWaalsContact O-CB 3.26Å; T130-M134 WeakPolarHBondContact O-CB 3.18Å; T130-M134 VanDerWaalsContact O-CG 3.25Å; T130-M134 WeakPolarHBondContact O-CG 3.39Å; T130-M134 PolarHBondContact O-N 3.2Å; T130-L223 HydrophobicContact CG2-CD1 3.48Å; T130-L223 VanDerWaalsContact CG2-CD1 3.48Å; T130-L226 HydrophobicContact CG2-CB 4.06Å; T130-L226 HydrophobicContact CG2-CD1 4.13Å; T130-L227 HydrophobicContact CG2-CD1 4.39Å; T130-L227 HydrophobicContact CG2-CD2 4.07Å; T130-L227 HydrophobicContact CG2-CG 4.02Å; T130-L227 WeakPolarHBondContact OG1-CD2 3.43Å
131R97.4Very high95.3Very high65 Ų6539.8 Ų39.825%0.24519%0.193CC..Hα-helixtrans-60-40.7175.9-176.1-171.7-64.1106.63.6112.4E127 E129 R135 F290 F291E127-R131 WeakPolarHBondContact O-CB 3.28Å; E127-R131 PolarHBondContact O-N 3.35Å; E129-R131 VanDerWaalsContact C-N 3.28Å; E129-R131 PolarHBondContact O-N 3.42Å; R131-R135 VanDerWaalsContact O-CB 3.32Å; R131-R135 WeakPolarHBondContact O-CB 3.41Å; R131-R135 PolarHBondContact O-N 2.83Å; R131-F290 HydrophobicContact CB-CE1 3.76Å; R131-F290 HydrophobicContact CB-CE2 4.49Å; R131-F290 HydrophobicContact CB-CZ 3.7Å; R131-F290 VanDerWaalsContact CD-O 3.27Å; R131-F290 WeakPolarHBondContact CD-O 3.3Å; R131-F290 HydrophobicContact CG-CD1 4.35Å; R131-F290 HydrophobicContact CG-CE1 4Å; R131-F290 HydrophobicContact CG-CZ 4.28Å; R131-F290 PolarHBondContact NE-O 3.41Å; R131-F291 HydrophobicContact CG-CD1 3.86Å; R131-F291 HydrophobicContact CG-CE1 4.29Å
132S96.4Very high95.8Very high53 Ų5337 Ų3737%0.37118%0.181SC..Hα-helixtrans-65.1-49.8178.2-161.80000110.9K128 E129 T130 R135 S136K128-S132 PolarHBondContact O-N 3.3Å; E129-S132 WeakPolarHBondContact O-CB 3.33Å; E129-S132 PolarHBondContact O-N 2.88Å; T130-S132 VanDerWaalsContact C-N 3.31Å; T130-S132 PolarHBondContact O-N 3.23Å; S132-R135 PolarHBondContact O-N 2.79Å; S132-S136 PolarHBondContact O-N 3.32Å; S132-S136 PolarHBondContact O-OG 3.35Å
133I98.2Very high96.4Very high8 Ų835.5 Ų35.54%0.04118%0.175CC..Hα-helixtrans-61.6-49.1-179.6-71.2163.3000110.9L115 L125 E129 T130 R135 S136 L137 I167 L226L115-I133 HydrophobicContact CD1-CD1 3.92Å; L115-I133 HydrophobicContact CD2-CG2 3.84Å; L125-I133 HydrophobicContact CD1-CD1 3.63Å; E129-I133 PolarHBondContact O-N 2.8Å; T130-I133 PolarHBondContact O-N 3.12Å; I133-R135 VanDerWaalsContact C-N 3.34Å; I133-R135 PolarHBondContact O-N 3.05Å; I133-S136 PolarHBondContact O-N 3.38Å; I133-L137 WeakPolarHBondContact O-CB 3.1Å; I133-L137 PolarHBondContact O-N 3.33Å; I133-I167 HydrophobicContact CG1-CG2 4.19Å; I133-I167 HydrophobicContact CG2-CG2 4.11Å; I133-L226 HydrophobicContact CG2-CD1 3.91Å
134M98.6Very high97Very high0 Ų034.7 Ų34.70%017%0.17CC..Hα-helixtrans-69.2-30.4-176.9-70-59.3-49.600113T130 L137 L138 C219 I222 L223 L226 F291T130-M134 HydrophobicContact CG2-CG 3.9Å; T130-M134 VanDerWaalsContact O-CB 3.26Å; T130-M134 WeakPolarHBondContact O-CB 3.18Å; T130-M134 VanDerWaalsContact O-CG 3.25Å; T130-M134 WeakPolarHBondContact O-CG 3.39Å; T130-M134 PolarHBondContact O-N 3.2Å; M134-L137 HydrophobicContact CE-CD2 3.95Å; M134-L137 HydrophobicContact SD-CD2 4.02Å; M134-L138 WeakPolarHBondContact O-CB 3.13Å; M134-L138 VanDerWaalsContact O-CG 3.28Å; M134-L138 WeakPolarHBondContact O-CG 3.34Å; M134-L138 PolarHBondContact O-N 3.25Å; M134-C219 HydrophobicContact CE-CB 4.11Å; M134-C219 WeakPolarHBondContact CE-O 3.49Å; M134-I222 HydrophobicContact SD-CG2 3.93Å; M134-L223 HydrophobicContact CE-CB 3.97Å; M134-L223 HydrophobicContact CG-CB 4.35Å; M134-L223 HydrophobicContact CG-CD1 3.87Å; M134-L223 HydrophobicContact SD-CB 4.04Å; M134-L226 HydrophobicContact CG-CD1 4.3Å; M134-L226 HydrophobicContact SD-CD1 4.04Å; M134-F291 HydrophobicContact CB-CE1 3.99Å; M134-F291 HydrophobicContact CB-CZ 3.97Å
135R98.4Very high97.4Very high68 Ų6835 Ų3526%0.25717%0.169SC..Hα-helixtrans-62.5-53.4173.4-178.9178.5-64.2114.6-3.4109.9R131 S132 I133 L137 L138 E139 L286 F291R131-R135 VanDerWaalsContact O-CB 3.32Å; R131-R135 WeakPolarHBondContact O-CB 3.41Å; R131-R135 PolarHBondContact O-N 2.83Å; S132-R135 PolarHBondContact O-N 2.79Å; I133-R135 VanDerWaalsContact C-N 3.34Å; I133-R135 PolarHBondContact O-N 3.05Å; R135-L137 VanDerWaalsContact C-N 3.27Å; R135-L137 PolarHBondContact O-N 3.44Å; R135-L138 PolarHBondContact O-N 3Å; R135-E139 WeakPolarHBondContact CD-OE1 3.43Å; R135-E139 HydrophobicContact CG-CG 4.42Å; R135-E139 VanDerWaalsContact CG-OE1 3.28Å; R135-E139 WeakPolarHBondContact CG-OE1 3.39Å; R135-E139 WeakPolarHBondContact O-CB 3.37Å; R135-E139 WeakPolarHBondContact O-CG 3.41Å; R135-E139 PolarHBondContact O-N 2.91Å; R135-L286 HydrophobicContact CG-CD2 4.02Å; R135-F291 HydrophobicContact CB-CD1 3.85Å; R135-F291 HydrophobicContact CB-CE1 3.91Å; R135-F291 HydrophobicContact CG-CD1 4.47Å; R135-F291 PolarHBondContact NH2-O 2.95Å
136S98.5Very high97.6Very high9 Ų938.5 Ų38.56%0.06320%0.198CC..Hα-helixtrans-60.7-36.7179.1-66.50000112.6H89 S132 I133 A140 I167H89-S136 VanDerWaalsContact CD2-CB 3.49Å; H89-S136 WeakPolarHBondContact CD2-CB 3.45Å; H89-S136 PolarHBondContact CE1-OG 2.93Å; H89-S136 PolarHBondContact NE2-OG 2.85Å; H89-S136 VanDerWaalsContact NE2-OG 3.07Å; S132-S136 PolarHBondContact O-N 3.32Å; S132-S136 PolarHBondContact O-OG 3.35Å; I133-S136 PolarHBondContact O-N 3.38Å; S136-A140 PolarHBondContact O-N 3.36Å; S136-I167 VanDerWaalsContact CB-CG1 3.48Å
137L98.8Very high97.8Very high0 Ų039.4 Ų39.40%020%0.199CC..Hα-helixtrans-65.7-48.6176.1179.761.8000111.2I133 M134 R135 E139 A140 V141 I159 I167 L169 I222I133-L137 WeakPolarHBondContact O-CB 3.1Å; I133-L137 PolarHBondContact O-N 3.33Å; M134-L137 HydrophobicContact CE-CD2 3.95Å; M134-L137 HydrophobicContact SD-CD2 4.02Å; R135-L137 VanDerWaalsContact C-N 3.27Å; R135-L137 PolarHBondContact O-N 3.44Å; L137-E139 VanDerWaalsContact C-N 3.32Å; L137-E139 PolarHBondContact O-N 2.69Å; L137-A140 WeakPolarHBondContact O-CB 3.49Å; L137-A140 PolarHBondContact O-N 3.32Å; L137-V141 HydrophobicContact CD1-CG2 4.38Å; L137-V141 WeakPolarHBondContact O-CG2 3.15Å; L137-V141 PolarHBondContact O-N 2.68Å; L137-I159 HydrophobicContact CD1-CD1 3.9Å; L137-I159 HydrophobicContact CD1-CG1 4.3Å; L137-I159 HydrophobicContact CD2-CD1 3.84Å; L137-I159 HydrophobicContact CG-CD1 4.46Å; L137-I167 HydrophobicContact CB-CD1 3.9Å; L137-I167 HydrophobicContact CD1-CD1 4.44Å; L137-L169 HydrophobicContact CD1-CD1 4.49Å; L137-I222 HydrophobicContact CD2-CD1 3.99Å; L137-I222 HydrophobicContact CD2-CG2 4.29Å
138L98.8Very high97.9Very high0 Ų039.6 Ų39.60%020%0.201CC..Hα-helixtrans-66.8-33178.8-71.3168.8000112.2M134 R135 V141 N142 L216 C219 A285 L286 F291M134-L138 WeakPolarHBondContact O-CB 3.13Å; M134-L138 VanDerWaalsContact O-CG 3.28Å; M134-L138 WeakPolarHBondContact O-CG 3.34Å; M134-L138 PolarHBondContact O-N 3.25Å; R135-L138 PolarHBondContact O-N 3Å; L138-V141 PolarHBondContact O-N 3.44Å; L138-N142 WeakPolarHBondContact O-CB 3.5Å; L138-N142 PolarHBondContact O-N 2.9Å; L138-L216 HydrophobicContact CD2-CD1 3.77Å; L138-C219 HydrophobicContact CD2-CB 4.24Å; L138-A285 HydrophobicContact CD1-CB 3.84Å; L138-A285 HydrophobicContact CD2-CB 4.12Å; L138-L286 HydrophobicContact CB-CD1 4.39Å; L138-L286 HydrophobicContact CB-CD2 3.73Å; L138-L286 HydrophobicContact CB-CG 3.84Å; L138-F291 HydrophobicContact CD1-CE2 3.54Å; L138-F291 HydrophobicContact CD1-CZ 3.47Å; L138-F291 VanDerWaalsContact CD1-CZ 3.47Å
139E98.7Very high98.1Very high67 Ų6731.8 Ų31.831%0.31317%0.167SC..Hα-helixtrans-62.4-45.1171.5-76.1166.9-179.900111.3H89 R135 L137 N142 F143 L286H89-E139 IonicContact CD2-OE2 2.86Å; H89-E139 PolarHBondContact CD2-OE2 3.43Å; H89-E139 IonicContact NE2-OE2 3.94Å; H89-E139 PolarHBondContact NE2-OE2 3.28Å; R135-E139 WeakPolarHBondContact CD-OE1 3.43Å; R135-E139 HydrophobicContact CG-CG 4.42Å; R135-E139 VanDerWaalsContact CG-OE1 3.28Å; R135-E139 WeakPolarHBondContact CG-OE1 3.39Å; R135-E139 WeakPolarHBondContact O-CB 3.37Å; R135-E139 WeakPolarHBondContact O-CG 3.41Å; R135-E139 PolarHBondContact O-N 2.91Å; L137-E139 VanDerWaalsContact C-N 3.32Å; L137-E139 PolarHBondContact O-N 2.69Å; E139-N142 PolarHBondContact O-N 3.47Å; E139-F143 WeakPolarHBondContact O-CB 3.4Å; E139-F143 PolarHBondContact O-N 2.93Å; E139-L286 HydrophobicContact CG-CD1 4.07Å; E139-L286 HydrophobicContact CG-CD2 3.94Å
140A98.8Very high98.3Very high0 Ų028.1 Ų28.10%015%0.15CC..Hα-helixtrans-61.8-47.4174.200000112H89 I90 S136 L137 N142 F143 L144 L169H89-A140 HydrophobicContact CB-CB 4.04Å; I90-A140 HydrophobicContact CD1-CB 4.37Å; I90-A140 HydrophobicContact CG1-CB 3.92Å; S136-A140 PolarHBondContact O-N 3.36Å; L137-A140 WeakPolarHBondContact O-CB 3.49Å; L137-A140 PolarHBondContact O-N 3.32Å; A140-N142 PolarHBondContact O-N 2.84Å; A140-F143 WeakPolarHBondContact O-CB 3.19Å; A140-F143 PolarHBondContact O-N 2.8Å; A140-L144 WeakPolarHBondContact O-CG 3.5Å; A140-L144 PolarHBondContact O-N 2.83Å; A140-L169 HydrophobicContact CB-CD2 4.46Å
141V98.8Very high98.3Very high0 Ų028.1 Ų28.10%015%0.15CC..Hα-helixtrans-62.6-42.9178.7173.10000111.2L137 L138 F143 L144 H145 L154 D215 L216 A282L137-V141 HydrophobicContact CD1-CG2 4.38Å; L137-V141 WeakPolarHBondContact O-CG2 3.15Å; L137-V141 PolarHBondContact O-N 2.68Å; L138-V141 PolarHBondContact O-N 3.44Å; V141-F143 VanDerWaalsContact C-N 3.3Å; V141-F143 PolarHBondContact O-N 3.37Å; V141-L144 PolarHBondContact O-N 2.95Å; V141-H145 VanDerWaalsContact CG1-CE1 3.47Å; V141-H145 WeakPolarHBondContact CG1-CE1 3.32Å; V141-H145 WeakPolarHBondContact O-CB 3.25Å; V141-H145 PolarHBondContact O-CD2 3.29Å; V141-H145 VanDerWaalsContact O-CG 3.29Å; V141-H145 PolarHBondContact O-N 3.47Å; V141-L154 HydrophobicContact CG2-CD1 3.69Å; V141-D215 HydrophobicContact CG1-CB 4.12Å; V141-L216 HydrophobicContact CG1-CD2 4.09Å; V141-A282 HydrophobicContact CG1-CB 4.15Å
142N98.7Very high98.3Very high56 Ų5625.8 Ų25.830%0.29914%0.141SC..Hα-helixtrans-59.7-42.6175.9-17059.1000111.6L138 E139 A140 H145 A146 A282 E283 L286L138-N142 WeakPolarHBondContact O-CB 3.5Å; L138-N142 PolarHBondContact O-N 2.9Å; E139-N142 PolarHBondContact O-N 3.47Å; A140-N142 PolarHBondContact O-N 2.84Å; N142-H145 PolarHBondContact O-N 3.04Å; N142-A146 WeakPolarHBondContact O-CB 3.27Å; N142-A146 PolarHBondContact O-N 3.32Å; N142-A282 HydrophobicContact CB-CB 3.69Å; N142-E283 PolarHBondContact OD1-N 2.9Å; N142-L286 HydrophobicContact CB-CD1 4.3Å
143F98.8Very high98.3Very high59 Ų5923.4 Ų23.426%0.25912%0.124SC..Hα-helixtrans-62.9-44.6175.1174-95.3000112.3V84 H87 I90 E139 A140 V141 H145 A146 N147V84-F143 HydrophobicContact CB-CE1 3.95Å; V84-F143 HydrophobicContact CG1-CE1 4.15Å; H87-F143 HydrophobicContact CB-CD1 4.08Å; H87-F143 HydrophobicContact CB-CE1 4.04Å; H87-F143 HydrophobicContact CB-CG 4.5Å; H87-F143 HydrophobicContact CB-CZ 4.43Å; H87-F143 AromaticContact CD2-CD1 3.85Å; H87-F143 AromaticContact CD2-CD2 3.74Å; H87-F143 AromaticContact CD2-CG 3.44Å; H87-F143 VanDerWaalsContact CD2-CG 3.44Å; H87-F143 WeakPolarHBondContact CD2-CG 3.08Å; I90-F143 HydrophobicContact CD1-CD1 3.68Å; I90-F143 HydrophobicContact CD1-CE1 4.14Å; E139-F143 WeakPolarHBondContact O-CB 3.4Å; E139-F143 PolarHBondContact O-N 2.93Å; A140-F143 WeakPolarHBondContact O-CB 3.19Å; A140-F143 PolarHBondContact O-N 2.8Å; V141-F143 VanDerWaalsContact C-N 3.3Å; V141-F143 PolarHBondContact O-N 3.37Å; F143-H145 PolarHBondContact O-N 2.84Å; F143-A146 PolarHBondContact O-N 2.85Å; F143-N147 WeakPolarHBondContact CE2-ND2 3.49Å; F143-N147 PolarHBondContact O-N 3.47Å; F143-N147 PolarHBondContact O-ND2 2.71Å
144L98.6Very high98.3Very high0 Ų023 Ų230%012%0.123CC..Hα-helixtrans-58.9-48.4175.2-67.4-179.5000111.4V84 I90 A140 V141 A146 N147 N148 I149 H151 L169 F172V84-L144 HydrophobicContact CB-CD2 4.29Å; V84-L144 HydrophobicContact CG1-CD2 3.49Å; V84-L144 VanDerWaalsContact CG1-CD2 3.49Å; I90-L144 HydrophobicContact CD1-CD2 3.79Å; I90-L144 HydrophobicContact CD1-CG 4.13Å; A140-L144 WeakPolarHBondContact O-CG 3.5Å; A140-L144 PolarHBondContact O-N 2.83Å; V141-L144 PolarHBondContact O-N 2.95Å; L144-A146 VanDerWaalsContact C-N 3.31Å; L144-A146 PolarHBondContact O-N 3.39Å; L144-N147 CarbonylContact O-C 3.48Å; L144-N147 WeakPolarHBondContact O-CA 3.25Å; L144-N147 PolarHBondContact O-N 3.48Å; L144-N148 PolarHBondContact O-N 2.78Å; L144-I149 CarbonylContact C-O 3.4Å; L144-I149 HydrophobicContact CB-CB 4.29Å; L144-I149 HydrophobicContact CB-CG2 4.5Å; L144-I149 HydrophobicContact CD2-CB 4.38Å; L144-I149 HydrophobicContact CD2-CD1 4.49Å; L144-I149 HydrophobicContact CD2-CG2 4.16Å; L144-I149 PolarHBondContact O-N 2.87Å; L144-H151 HydrophobicContact CD1-CB 4.27Å; L144-L169 HydrophobicContact CD1-CD2 3.81Å; L144-F172 HydrophobicContact CD1-CE1 3.85Å; L144-F172 HydrophobicContact CD1-CZ 4.35Å; L144-F172 HydrophobicContact CD2-CE1 3.74Å; L144-F172 HydrophobicContact CD2-CZ 4.3Å; L144-F172 HydrophobicContact CG-CE1 4.45Å
145H98.4Very high98.3Very high24 Ų2424.4 Ų24.411%0.11113%0.129CC..Hα-helixtrans-65.4-35.3-177-71.2-169.9000112.3V141 N142 F143 N147 N148 I149 K212 D215 L216V141-H145 VanDerWaalsContact CG1-CE1 3.47Å; V141-H145 WeakPolarHBondContact CG1-CE1 3.32Å; V141-H145 WeakPolarHBondContact O-CB 3.25Å; V141-H145 PolarHBondContact O-CD2 3.29Å; V141-H145 VanDerWaalsContact O-CG 3.29Å; V141-H145 PolarHBondContact O-N 3.47Å; N142-H145 PolarHBondContact O-N 3.04Å; F143-H145 PolarHBondContact O-N 2.84Å; H145-N147 PolarHBondContact O-N 2.84Å; H145-N148 PolarHBondContact O-N 2.87Å; H145-N148 VanDerWaalsContact O-N 3.16Å; H145-I149 PolarHBondContact CD2-O 3.44Å; H145-I149 VanDerWaalsContact CD2-O 3.3Å; H145-K212 HydrophobicContact CB-CD 3.98Å; H145-K212 PolarHBondContact CE1-O 3.41Å; H145-K212 PolarHBondContact NE2-O 3.04Å; H145-K212 PolarHBondContact O-NZ 3.37Å; H145-D215 IonicContact CD2-OD2 3.46Å; H145-D215 IonicContact CE1-OD2 3.84Å; H145-D215 IonicContact NE2-OD2 3.43Å; H145-D215 PolarHBondContact NE2-OD2 3.05Å; H145-L216 WeakPolarHBondContact CE1-CD2 3.48Å
146A97.8Very high98.2Very high76 Ų7621.2 Ų21.263%0.62812%0.117SC*.Hα-helixtrans-65.8-26.417300000113.1N142 F143 L144 N148N142-A146 WeakPolarHBondContact O-CB 3.27Å; N142-A146 PolarHBondContact O-N 3.32Å; F143-A146 PolarHBondContact O-N 2.85Å; L144-A146 VanDerWaalsContact C-N 3.31Å; L144-A146 PolarHBondContact O-N 3.39Å; A146-N148 VanDerWaalsContact C-N 3.33Å
147N97.7Very high98Very high69 Ų6923.2 Ų23.237%0.36913%0.125SC..THydrogen-bonded Turntrans-94.417.3174.2-71.1-82.6000112.9F143 L144 H145 I149F143-N147 WeakPolarHBondContact CE2-ND2 3.49Å; F143-N147 PolarHBondContact O-N 3.47Å; F143-N147 PolarHBondContact O-ND2 2.71Å; L144-N147 CarbonylContact O-C 3.48Å; L144-N147 WeakPolarHBondContact O-CA 3.25Å; L144-N147 PolarHBondContact O-N 3.48Å; H145-N147 PolarHBondContact O-N 2.84Å; N147-I149 HydrophobicContact CB-CD1 4.05Å; N147-I149 PolarHBondContact O-N 3.41Å
148N98Very high97.9Very high37 Ų3723.7 Ų23.720%0.19813%0.128CC..THydrogen-bonded Turntrans58.228-177.8-65.4-27.6000114.6L144 H145 A146 H177 L178 E179 K212L144-N148 PolarHBondContact O-N 2.78Å; H145-N148 PolarHBondContact O-N 2.87Å; H145-N148 VanDerWaalsContact O-N 3.16Å; A146-N148 VanDerWaalsContact C-N 3.33Å; N148-H177 CarbonylContact O-C 3.55Å; N148-H177 VanDerWaalsContact O-CA 3.26Å; N148-H177 WeakPolarHBondContact O-CA 3.26Å; N148-L178 WeakPolarHBondContact CB-O 3.39Å; N148-L178 PolarHBondContact O-N 2.87Å; N148-E179 PolarHBondContact ND2-OE2 2.76Å; N148-K212 PolarHBondContact OD1-NZ 2.84Å
149I98.4Very high97.8Very high0 Ų023.7 Ų23.70%013%0.128CC..EExtended strand (participates in β ladder)trans-105.1133.7176.7-62.4158.2000109I80 V84 L144 H145 N147 C176I80-I149 HydrophobicContact CG2-CD1 4.25Å; I80-I149 HydrophobicContact CG2-CG2 4.1Å; V84-I149 HydrophobicContact CG1-CD1 3.62Å; L144-I149 CarbonylContact C-O 3.4Å; L144-I149 HydrophobicContact CB-CB 4.29Å; L144-I149 HydrophobicContact CB-CG2 4.5Å; L144-I149 HydrophobicContact CD2-CB 4.38Å; L144-I149 HydrophobicContact CD2-CD1 4.49Å; L144-I149 HydrophobicContact CD2-CG2 4.16Å; L144-I149 PolarHBondContact O-N 2.87Å; H145-I149 PolarHBondContact CD2-O 3.44Å; H145-I149 VanDerWaalsContact CD2-O 3.3Å; N147-I149 HydrophobicContact CB-CD1 4.05Å; N147-I149 PolarHBondContact O-N 3.41Å; I149-C176 WeakPolarHBondContact CA-O 2.93Å
150V98.2Very high97.8Very high0 Ų022.2 Ų22.20%012%0.122CC..EExtended strand (participates in β ladder)trans-112.6134.8169.659.40000109.2R152 S175 C176 L178 L184 K212 V214 D215V150-R152 HydrophobicContact CB-CG 4.36Å; V150-R152 HydrophobicContact CG1-CG 3.93Å; V150-R152 HydrophobicContact CG2-CG 3.72Å; V150-S175 VanDerWaalsContact O-CA 3.23Å; V150-S175 WeakPolarHBondContact O-CA 3.46Å; V150-S175 WeakPolarHBondContact O-CB 3.35Å; V150-C176 PolarHBondContact N-O 3.38Å; V150-C176 PolarHBondContact O-N 3.34Å; V150-L178 HydrophobicContact CG1-CB 4.28Å; V150-L184 HydrophobicContact CG1-CD1 3.77Å; V150-K212 HydrophobicContact CB-CG 4.5Å; V150-V214 HydrophobicContact CG2-CG2 3.95Å; V150-D215 WeakPolarHBondContact CG2-OD2 3.45Å
151H98.4Very high97.7Very high0 Ų022.2 Ų22.20%012%0.122CC..  trans-81.6-43-173.2-171.4-75.8000112.9L144 D153 L154 S170 D171 F172 F174 S175 D215L144-H151 HydrophobicContact CD1-CB 4.27Å; H151-D153 PolarHBondContact CE1-O 2.85Å; H151-D153 VanDerWaalsContact ND1-C 3.33Å; H151-D153 PolarHBondContact ND1-N 3.4Å; H151-D153 PolarHBondContact O-N 3.17Å; H151-L154 HydrophobicContact CB-CD2 3.89Å; H151-L154 HydrophobicContact CB-CG 4Å; H151-L154 VanDerWaalsContact CG-CD2 3.5Å; H151-L154 PolarHBondContact ND1-N 3.31Å; H151-S170 PolarHBondContact NE2-O 3.46Å; H151-D171 PolarHBondContact CE1-O 3.07Å; H151-D171 PolarHBondContact NE2-O 3.36Å; H151-F172 AromaticContact CD2-CE1 3.88Å; H151-F174 CarbonylContact O-C 3.47Å; H151-S175 WeakPolarHBondContact CA-OG 3.46Å; H151-S175 PolarHBondContact O-OG 3.3Å; H151-D215 PolarHBondContact N-OD1 3.36Å; H151-D215 PolarHBondContact N-OD2 3.28Å
152R97.4Very high97.5Very high15 Ų1523.8 Ų23.86%0.05713%0.13CC..SBendtrans67.7-15.9176.5-54.2-168-68.3166.73.3117.3V150 F174 E186 C188 Y210 D215V150-R152 HydrophobicContact CB-CG 4.36Å; V150-R152 HydrophobicContact CG1-CG 3.93Å; V150-R152 HydrophobicContact CG2-CG 3.72Å; R152-F174 HydrophobicContact CB-CB 4.36Å; R152-F174 PolarHBondContact NE-O 3.15Å; R152-F174 PolarHBondContact NH2-O 2.85Å; R152-E186 IonicContact CZ-OE2 3.41Å; R152-E186 IonicContact NH1-OE2 2.75Å; R152-E186 PolarHBondContact NH1-OE2 3.34Å; R152-E186 IonicContact NH2-OE2 3.16Å; R152-E186 PolarHBondContact NH2-OE2 2.94Å; R152-E186 VanDerWaalsContact NH2-OE2 3.16Å; R152-C188 VanDerWaalsContact CZ-SG 3.54Å; R152-C188 PolarHBondContact NH1-SG 2.87Å; R152-Y210 PolarHBondContact NH1-OH 3.09Å; R152-D215 PolarHBondContact N-OD1 2.95Å
153D96.9Very high97.1Very high3 Ų325.4 Ų25.42%0.01614%0.139CC..  trans-130.551.2174.3-165.141.5000113.5H151 K155 N158 F174 G189 T190H151-D153 PolarHBondContact CE1-O 2.85Å; H151-D153 VanDerWaalsContact ND1-C 3.33Å; H151-D153 PolarHBondContact ND1-N 3.4Å; H151-D153 PolarHBondContact O-N 3.17Å; D153-K155 PolarHBondContact O-N 3.46Å; D153-K155 IonicContact OD1-NZ 3.53Å; D153-K155 PolarHBondContact OD1-NZ 2.84Å; D153-K155 WeakPolarHBondContact OD2-CE 3.31Å; D153-K155 IonicContact OD2-NZ 3.52Å; D153-K155 PolarHBondContact OD2-NZ 3.49Å; D153-N158 PolarHBondContact O-ND2 3.4Å; D153-N158 PolarHBondContact OD2-ND2 3.27Å; D153-N158 VanDerWaalsContact OD2-ND2 3.12Å; D153-F174 HydrophobicContact CB-CB 4.26Å; D153-F174 HydrophobicContact CB-CD2 3.63Å; D153-F174 HydrophobicContact CB-CE2 4.44Å; D153-F174 HydrophobicContact CB-CG 4.31Å; D153-G189 WeakPolarHBondContact OD1-CA 3.39Å; D153-T190 WeakPolarHBondContact OD1-CB 3.41Å; D153-T190 PolarHBondContact OD1-N 3.1Å; D153-T190 PolarHBondContact OD1-OG1 3.16Å
154L98.5Very high96.8Very high1 Ų128.6 Ų28.61%0.00516%0.158CC..  trans-73.9120.2174.8-66.8179.8000111.1V141 H151 L169 D215 A218 I222V141-L154 HydrophobicContact CG2-CD1 3.69Å; H151-L154 HydrophobicContact CB-CD2 3.89Å; H151-L154 HydrophobicContact CB-CG 4Å; H151-L154 VanDerWaalsContact CG-CD2 3.5Å; H151-L154 PolarHBondContact ND1-N 3.31Å; L154-L169 HydrophobicContact CD2-CD1 3.45Å; L154-L169 VanDerWaalsContact CD2-CD1 3.45Å; L154-L169 HydrophobicContact CD2-CD2 3.8Å; L154-L169 HydrophobicContact CD2-CG 4.26Å; L154-D215 HydrophobicContact CD1-CB 3.61Å; L154-D215 WeakPolarHBondContact CD1-O 3.3Å; L154-A218 HydrophobicContact CB-CB 3.75Å; L154-I222 HydrophobicContact CB-CD1 4.17Å
155K97Very high96.5Very high29 Ų2930.8 Ų30.813%0.12617%0.169CC..  trans-157.3160.3177.662.7-169.7-177.5-149.30111.1D153 E157 N158 T190 Y193D153-K155 PolarHBondContact O-N 3.46Å; D153-K155 IonicContact OD1-NZ 3.53Å; D153-K155 PolarHBondContact OD1-NZ 2.84Å; D153-K155 WeakPolarHBondContact OD2-CE 3.31Å; D153-K155 IonicContact OD2-NZ 3.52Å; D153-K155 PolarHBondContact OD2-NZ 3.49Å; K155-E157 WeakPolarHBondContact CB-OE2 3.03Å; K155-E157 HydrophobicContact CD-CB 4.32Å; K155-E157 HydrophobicContact CG-CB 4.09Å; K155-E157 WeakPolarHBondContact CG-OE2 3.34Å; K155-E157 PolarHBondContact O-N 3.42Å; K155-E157 VanDerWaalsContact O-N 3.16Å; K155-N158 WeakPolarHBondContact CE-ND2 3.34Å; K155-N158 VanDerWaalsContact CE-OD1 3.31Å; K155-N158 WeakPolarHBondContact CE-OD1 3.46Å; K155-N158 HydrophobicContact CG-CB 4.11Å; K155-N158 PolarHBondContact O-N 3.01Å; K155-T190 HydrophobicContact CD-CG2 4.37Å; K155-T190 VanDerWaalsContact CD-OG1 3.25Å; K155-T190 WeakPolarHBondContact CD-OG1 3.32Å; K155-T190 PolarHBondContact NZ-OG1 3.05Å; K155-Y193 HydrophobicContact CB-CD1 4.27Å; K155-Y193 HydrophobicContact CB-CD2 3.82Å; K155-Y193 HydrophobicContact CB-CE1 4.16Å; K155-Y193 HydrophobicContact CB-CE2 3.66Å; K155-Y193 HydrophobicContact CB-CG 4.13Å
156P96.7Very high96.3Very high1 Ų133.3 Ų33.31%0.00618%0.181CC..G310 helixtrans-57.7-25.8179.9-25.436.5000114.8L115 F116 N158 I159 Y193 I222L115-P156 HydrophobicContact CB-CB 4.49Å; L115-P156 WeakPolarHBondContact CB-O 3.45Å; L115-P156 HydrophobicContact CG-CB 4.39Å; L115-P156 PolarHBondContact N-O 3.33Å; F116-P156 HydrophobicContact CB-CB 3.98Å; F116-P156 HydrophobicContact CD2-CB 4.47Å; F116-P156 PolarHBondContact N-O 2.78Å; F116-P156 VanDerWaalsContact N-O 3.1Å; P156-N158 VanDerWaalsContact C-N 3.29Å; P156-I159 PolarHBondContact O-N 2.88Å; P156-Y193 VanDerWaalsContact CD-CZ 3.44Å; P156-Y193 WeakPolarHBondContact CD-OH 3.44Å; P156-I222 HydrophobicContact CG-CG1 4.36Å
157E94.1Very high96.3Very high51 Ų5129.8 Ų29.824%0.23815%0.151CC..G310 helixtrans-67-31.6175.3-60.486.5155.900111.5F116 K155 I159F116-E157 HydrophobicContact CB-CG 3.91Å; F116-E157 HydrophobicContact CD2-CG 4.16Å; F116-E157 HydrophobicContact CG-CG 4Å; K155-E157 WeakPolarHBondContact CB-OE2 3.03Å; K155-E157 HydrophobicContact CD-CB 4.32Å; K155-E157 HydrophobicContact CG-CB 4.09Å; K155-E157 WeakPolarHBondContact CG-OE2 3.34Å; K155-E157 PolarHBondContact O-N 3.42Å; K155-E157 VanDerWaalsContact O-N 3.16Å; E157-I159 VanDerWaalsContact C-N 3.35Å
158N96.6Very high96.3Very high10 Ų1029.1 Ų29.15%0.05314%0.144CC..G310 helixtrans-92.35.2-178.3-68.31000112.7D153 K155 P156 S170 D171D153-N158 PolarHBondContact O-ND2 3.4Å; D153-N158 PolarHBondContact OD2-ND2 3.27Å; D153-N158 VanDerWaalsContact OD2-ND2 3.12Å; K155-N158 WeakPolarHBondContact CE-ND2 3.34Å; K155-N158 VanDerWaalsContact CE-OD1 3.31Å; K155-N158 WeakPolarHBondContact CE-OD1 3.46Å; K155-N158 HydrophobicContact CG-CB 4.11Å; K155-N158 PolarHBondContact O-N 3.01Å; P156-N158 VanDerWaalsContact C-N 3.29Å; N158-S170 PolarHBondContact O-N 3.3Å; N158-S170 PolarHBondContact O-OG 2.96Å; N158-D171 HydrophobicContact CB-CB 4.33Å
159I98.3Very high96.4Very high0 Ų027.3 Ų27.30%013%0.134CC..EExtended strand (participates in β ladder)trans-112.2113.8177.1-59.9167.2000108.2L115 L137 P156 E157 I167 L169 I222L115-I159 HydrophobicContact CB-CB 4Å; L115-I159 HydrophobicContact CB-CG2 4.1Å; L115-I159 VanDerWaalsContact CB-O 3.25Å; L115-I159 WeakPolarHBondContact CB-O 3.29Å; L115-I159 HydrophobicContact CD2-CB 4.03Å; L115-I159 HydrophobicContact CD2-CD1 4Å; L115-I159 HydrophobicContact CD2-CG2 3.83Å; L115-I159 PolarHBondContact N-O 3.46Å; L137-I159 HydrophobicContact CD1-CD1 3.9Å; L137-I159 HydrophobicContact CD1-CG1 4.3Å; L137-I159 HydrophobicContact CD2-CD1 3.84Å; L137-I159 HydrophobicContact CG-CD1 4.46Å; P156-I159 PolarHBondContact O-N 2.88Å; E157-I159 VanDerWaalsContact C-N 3.35Å; I159-I167 HydrophobicContact CG2-CB 3.67Å; I159-I167 HydrophobicContact CG2-CD1 3.92Å; I159-I167 HydrophobicContact CG2-CG1 4.44Å; I159-I167 HydrophobicContact CG2-CG2 3.67Å; I159-L169 HydrophobicContact CG1-CD1 4.3Å; I159-I222 HydrophobicContact CD1-CD1 4.04Å; I159-I222 HydrophobicContact CD1-CG2 4.45Å
160L97.5Very high96.2Very high36 Ų3628 Ų2819%0.18814%0.139CC..EExtended strand (participates in β ladder)trans-98.8152.5-176.4-58.1177000111.9I91 M110 G113 E114 I167 R168I91-L160 HydrophobicContact CD1-CD1 4.35Å; M110-L160 HydrophobicContact CB-CB 3.63Å; M110-L160 HydrophobicContact CB-CD1 4.1Å; M110-L160 HydrophobicContact CB-CG 4.41Å; M110-L160 HydrophobicContact CE-CB 4.04Å; M110-L160 WeakPolarHBondContact CE-O 3.34Å; M110-L160 HydrophobicContact CG-CB 3.59Å; M110-L160 HydrophobicContact CG-CD1 3.8Å; M110-L160 HydrophobicContact CG-CG 4.35Å; G113-L160 CarbonylContact O-C 3.56Å; G113-L160 VanDerWaalsContact O-CA 3.32Å; G113-L160 WeakPolarHBondContact O-CA 3.42Å; E114-L160 HydrophobicContact CG-CD2 4.12Å; L160-I167 CarbonylContact O-C 3.54Å; L160-I167 WeakPolarHBondContact O-CA 3.32Å; L160-R168 PolarHBondContact N-O 2.89Å; L160-R168 PolarHBondContact O-N 2.52Å
161L97.1Very high95.9Very high0 Ų030.9 Ų30.90%016%0.155CC..EExtended strand (participates in β ladder)trans-118.6134.5-177.7-70.4164.8000112.2M110 K112 G113 L115 Y118 M165 Q166 I167M110-L161 CarbonylContact C-O 3.56Å; M110-L161 VanDerWaalsContact CE-C 3.5Å; K112-L161 WeakPolarHBondContact CA-O 3.36Å; K112-L161 HydrophobicContact CB-CB 3.68Å; K112-L161 WeakPolarHBondContact CB-O 3.46Å; K112-L161 PolarHBondContact N-O 2.73Å; G113-L161 PolarHBondContact O-N 3.08Å; L115-L161 HydrophobicContact CB-CD1 4.36Å; L115-L161 HydrophobicContact CD1-CD1 4.03Å; Y118-L161 HydrophobicContact CD1-CD1 3.99Å; Y118-L161 HydrophobicContact CD2-CD1 4.4Å; Y118-L161 HydrophobicContact CG-CD1 3.71Å; L161-M165 HydrophobicContact CD1-CE 4.04Å; L161-M165 HydrophobicContact CD2-CE 4.11Å; L161-Q166 WeakPolarHBondContact CA-O 3.24Å; L161-I167 HydrophobicContact CD2-CG2 3.62Å
162D93.9Very high95.8Very high33 Ų3330.9 Ų30.918%0.17616%0.155CC..  trans-90-178.8171.274.28.5000112.3M110 K112 N164 M165 Q166M110-D162 HydrophobicContact CE-CB 3.91Å; M110-D162 HydrophobicContact SD-CB 4.31Å; K112-D162 VanDerWaalsContact CD-O 3.3Å; K112-D162 WeakPolarHBondContact CD-O 3.48Å; K112-D162 WeakPolarHBondContact CG-O 3.4Å; D162-N164 PolarHBondContact O-N 3.07Å; D162-N164 VanDerWaalsContact OD1-C 3.22Å; D162-N164 VanDerWaalsContact OD1-CA 3.26Å; D162-N164 WeakPolarHBondContact OD1-CA 3.42Å; D162-N164 WeakPolarHBondContact OD1-CB 3.15Å; D162-N164 PolarHBondContact OD1-N 3.18Å; D162-M165 PolarHBondContact O-N 3.45Å; D162-M165 VanDerWaalsContact O-N 3.13Å; D162-M165 PolarHBondContact OD1-N 2.96Å; D162-Q166 PolarHBondContact N-O 2.94Å; D162-Q166 VanDerWaalsContact N-O 3.08Å; D162-Q166 PolarHBondContact OD1-N 2.95Å; D162-Q166 WeakPolarHBondContact OD2-CB 3.42Å
163D91.1Very high95.4Very high90 Ų9031.6 Ų31.648%0.48117%0.167SC..THydrogen-bonded Turntrans-59.3-30.9178.8-65.5-56.2000112.9R111 K112 M165R111-D163 VanDerWaalsContact CD-OD2 3.24Å; R111-D163 WeakPolarHBondContact CD-OD2 3.2Å; R111-D163 IonicContact NE-OD2 2.67Å; R111-D163 PolarHBondContact NE-OD2 3.44Å; K112-D163 WeakPolarHBondContact CE-O 3.21Å; K112-D163 PolarHBondContact NZ-O 3.23Å; D163-M165 VanDerWaalsContact C-N 3.32Å; D163-M165 PolarHBondContact O-N 3.36Å
164N91.8Very high95.2Very high125 Ų12534.7 Ų34.767%0.66818%0.18SC*.THydrogen-bonded Turntrans-88.68.2-178.4-59.6104.5000113.6D162 Q166D162-N164 PolarHBondContact O-N 3.07Å; D162-N164 VanDerWaalsContact OD1-C 3.22Å; D162-N164 VanDerWaalsContact OD1-CA 3.26Å; D162-N164 WeakPolarHBondContact OD1-CA 3.42Å; D162-N164 WeakPolarHBondContact OD1-CB 3.15Å; D162-N164 PolarHBondContact OD1-N 3.18Å; N164-Q166 HydrophobicContact CB-CG 4.19Å; N164-Q166 PolarHBondContact O-N 3.33Å; N164-Q166 PolarHBondContact O-NE2 2.77Å
165M91.9Very high95.1Very high47 Ų4734.8 Ų34.823%0.23218%0.181CC..SBendtrans60.522.5-175.6-59.1-63.9-54.300113.4K112 Y118 L161 D162 D163K112-M165 HydrophobicContact CD-SD 3.5Å; K112-M165 WeakPolarHBondContact CD-SD 3.42Å; K112-M165 PolarHBondContact NZ-SD 2.99Å; Y118-M165 HydrophobicContact CD1-CE 3.9Å; Y118-M165 HydrophobicContact CD2-CE 3.99Å; Y118-M165 HydrophobicContact CE1-CE 3.42Å; Y118-M165 VanDerWaalsContact CE1-CE 3.42Å; Y118-M165 HydrophobicContact CE2-CE 3.52Å; Y118-M165 HydrophobicContact CE2-SD 4.1Å; Y118-M165 HydrophobicContact CG-CE 4.16Å; L161-M165 HydrophobicContact CD1-CE 4.04Å; L161-M165 HydrophobicContact CD2-CE 4.11Å; D162-M165 PolarHBondContact O-N 3.45Å; D162-M165 VanDerWaalsContact O-N 3.13Å; D162-M165 PolarHBondContact OD1-N 2.96Å; D163-M165 VanDerWaalsContact C-N 3.32Å; D163-M165 PolarHBondContact O-N 3.36Å
166Q94.8Very high95.1Very high76 Ų7634.2 Ų34.236%0.35518%0.18SC..  trans-82141.9168.9-54.7-55.2-58.400108.9L161 D162 N164L161-Q166 WeakPolarHBondContact CA-O 3.24Å; D162-Q166 PolarHBondContact N-O 2.94Å; D162-Q166 VanDerWaalsContact N-O 3.08Å; D162-Q166 PolarHBondContact OD1-N 2.95Å; D162-Q166 WeakPolarHBondContact OD2-CB 3.42Å; N164-Q166 HydrophobicContact CB-CG 4.19Å; N164-Q166 PolarHBondContact O-N 3.33Å; N164-Q166 PolarHBondContact O-NE2 2.77Å
167I98.1Very high95.1Very high2 Ų237.4 Ų37.41%0.0120%0.195CC..EExtended strand (participates in β ladder)trans-90.5150.317965.3138.7000111.6H89 I133 S136 L137 I159 L160 L161H89-I167 WeakPolarHBondContact CA-O 3.43Å; H89-I167 PolarHBondContact ND1-O 3.36Å; I133-I167 HydrophobicContact CG1-CG2 4.19Å; I133-I167 HydrophobicContact CG2-CG2 4.11Å; S136-I167 VanDerWaalsContact CB-CG1 3.48Å; L137-I167 HydrophobicContact CB-CD1 3.9Å; L137-I167 HydrophobicContact CD1-CD1 4.44Å; I159-I167 HydrophobicContact CG2-CB 3.67Å; I159-I167 HydrophobicContact CG2-CD1 3.92Å; I159-I167 HydrophobicContact CG2-CG1 4.44Å; I159-I167 HydrophobicContact CG2-CG2 3.67Å; L160-I167 CarbonylContact O-C 3.54Å; L160-I167 WeakPolarHBondContact O-CA 3.32Å; L161-I167 HydrophobicContact CD2-CG2 3.62Å
168R98.4Very high95.2Very high55 Ų5535.3 Ų35.321%0.20819%0.185CC..EExtended strand (participates in β ladder)trans-127.9125.9158.2-64.4-174.1-177.5-99.95.6109.6H89 I90 I91 D108 M110 L160H89-R168 WeakPolarHBondContact O-CA 3.12Å; I90-R168 PolarHBondContact O-NH1 2.7Å; I91-R168 HydrophobicContact CB-CB 4.49Å; I91-R168 HydrophobicContact CD1-CB 4.39Å; D108-R168 IonicContact OD2-CZ 2.82Å; D108-R168 IonicContact OD2-NE 3.84Å; D108-R168 IonicContact OD2-NH1 2.86Å; D108-R168 PolarHBondContact OD2-NH1 2.87Å; D108-R168 IonicContact OD2-NH2 3.33Å; M110-R168 HydrophobicContact CE-CB 3.74Å; M110-R168 HydrophobicContact CE-CG 3.58Å; M110-R168 HydrophobicContact SD-CB 4.3Å; M110-R168 VanDerWaalsContact SD-CD 3.54Å; M110-R168 HydrophobicContact SD-CG 4Å; L160-R168 PolarHBondContact N-O 2.89Å; L160-R168 PolarHBondContact O-N 2.52Å
169L98.5Very high95.1Very high0 Ų039.2 Ų39.20%020%0.203CC..EExtended strand (participates in β ladder)trans-68.8136.2169.9-179.760.4000109.5H89 I90 I91 L137 A140 L144 L154 I159 F172H89-L169 PolarHBondContact O-N 3.12Å; I90-L169 HydrophobicContact CG1-CB 4.49Å; I91-L169 WeakPolarHBondContact CB-O 3.47Å; I91-L169 WeakPolarHBondContact CG2-O 3.44Å; I91-L169 PolarHBondContact N-O 3.37Å; L137-L169 HydrophobicContact CD1-CD1 4.49Å; A140-L169 HydrophobicContact CB-CD2 4.46Å; L144-L169 HydrophobicContact CD1-CD2 3.81Å; L154-L169 HydrophobicContact CD2-CD1 3.45Å; L154-L169 VanDerWaalsContact CD2-CD1 3.45Å; L154-L169 HydrophobicContact CD2-CD2 3.8Å; L154-L169 HydrophobicContact CD2-CG 4.26Å; I159-L169 HydrophobicContact CG1-CD1 4.3Å; L169-F172 HydrophobicContact CD2-CZ 4.35Å; L169-F172 HydrophobicContact CG-CZ 4.32Å
170S95.9Very high94.7Very high15 Ų1544 Ų4411%0.10524%0.235CC..  trans-139.5175.4-175.366.90000111H151 N158H151-S170 PolarHBondContact NE2-O 3.46Å; N158-S170 PolarHBondContact O-N 3.3Å; N158-S170 PolarHBondContact O-OG 2.96Å
171D91.3Very high94.2Very high60 Ų6046.2 Ų46.232%0.32127%0.265SS..  trans63.178.4177.8-158.45000114.7H151 N158 G173H151-D171 PolarHBondContact CE1-O 3.07Å; H151-D171 PolarHBondContact NE2-O 3.36Å; N158-D171 HydrophobicContact CB-CB 4.33Å; D171-G173 VanDerWaalsContact C-N 3.3Å; D171-G173 PolarHBondContact O-N 3.18Å
172F95Very high94.1Very high0 Ų051.4 Ų51.40%029%0.29CS..  trans-91.815.7-179-72.3-98.3000112.7E77 I80 L81 V84 I90 I91 L144 H151 L169 F174 S175E77-F172 HydrophobicContact CG-CB 4.07Å; I80-F172 HydrophobicContact CG2-CB 4.28Å; I80-F172 HydrophobicContact CG2-CD1 3.55Å; I80-F172 HydrophobicContact CG2-CE1 4.22Å; I80-F172 HydrophobicContact CG2-CG 4.14Å; L81-F172 HydrophobicContact CD2-CD2 3.55Å; L81-F172 HydrophobicContact CD2-CE2 4.03Å; L81-F172 HydrophobicContact CD2-CG 4.22Å; L81-F172 HydrophobicContact CG-CB 4.47Å; L81-F172 HydrophobicContact CG-CD2 4.32Å; V84-F172 HydrophobicContact CG2-CZ 4.36Å; I90-F172 HydrophobicContact CG2-CE2 3.75Å; I90-F172 HydrophobicContact CG2-CZ 3.57Å; I91-F172 HydrophobicContact CG2-CE2 4.41Å; L144-F172 HydrophobicContact CD1-CE1 3.85Å; L144-F172 HydrophobicContact CD1-CZ 4.35Å; L144-F172 HydrophobicContact CD2-CE1 3.74Å; L144-F172 HydrophobicContact CD2-CZ 4.3Å; L144-F172 HydrophobicContact CG-CE1 4.45Å; H151-F172 AromaticContact CD2-CE1 3.88Å; L169-F172 HydrophobicContact CD2-CZ 4.35Å; L169-F172 HydrophobicContact CG-CZ 4.32Å; F172-F174 PolarHBondContact O-N 3.18Å; F172-S175 WeakPolarHBondContact CA-OG 3.12Å; F172-S175 VanDerWaalsContact CD1-OG 3.27Å; F172-S175 WeakPolarHBondContact CD1-OG 3.28Å; F172-S175 VanDerWaalsContact O-CB 3.29Å; F172-S175 WeakPolarHBondContact O-CB 3.49Å; F172-S175 PolarHBondContact O-N 3.46Å; F172-S175 PolarHBondContact O-OG 3.37Å
173G90.9Very high94.2Very high30 Ų3054.5 Ų54.531%0.30930%0.302SS..THydrogen-bonded Turntrans-60.9-28.4-175.200000114.3D171D171-G173 VanDerWaalsContact C-N 3.3Å; D171-G173 PolarHBondContact O-N 3.18Å
174F92.1Very high94.4Very high68 Ų6851.8 Ų51.830%0.29829%0.287SS..THydrogen-bonded Turntrans-96.3-2.1172.8-66.5-68.1000113.6H151 R152 D153 F172 C188H151-F174 CarbonylContact O-C 3.47Å; R152-F174 HydrophobicContact CB-CB 4.36Å; R152-F174 PolarHBondContact NE-O 3.15Å; R152-F174 PolarHBondContact NH2-O 2.85Å; D153-F174 HydrophobicContact CB-CB 4.26Å; D153-F174 HydrophobicContact CB-CD2 3.63Å; D153-F174 HydrophobicContact CB-CE2 4.44Å; D153-F174 HydrophobicContact CB-CG 4.31Å; F172-F174 PolarHBondContact O-N 3.18Å; F174-C188 HydrophobicContact CD1-CB 3.69Å; F174-C188 HydrophobicContact CE1-CB 3.99Å; F174-C188 HydrophobicContact CG-CB 4.46Å
175S96.5Very high94.6Very high2 Ų251.1 Ų51.11%0.01428%0.275CS..  trans-73149.6-176.4-58.20000111.9I80 V150 H151 F172I80-S175 WeakPolarHBondContact CD1-O 3.45Å; V150-S175 VanDerWaalsContact O-CA 3.23Å; V150-S175 WeakPolarHBondContact O-CA 3.46Å; V150-S175 WeakPolarHBondContact O-CB 3.35Å; H151-S175 WeakPolarHBondContact CA-OG 3.46Å; H151-S175 PolarHBondContact O-OG 3.3Å; F172-S175 WeakPolarHBondContact CA-OG 3.12Å; F172-S175 VanDerWaalsContact CD1-OG 3.27Å; F172-S175 WeakPolarHBondContact CD1-OG 3.28Å; F172-S175 VanDerWaalsContact O-CB 3.29Å; F172-S175 WeakPolarHBondContact O-CB 3.49Å; F172-S175 PolarHBondContact O-N 3.46Å; F172-S175 PolarHBondContact O-OG 3.37Å
176C96.1Very high94.6Very high18 Ų1854 Ų5412%0.12229%0.288CS..EExtended strand (participates in β ladder)trans-149.4162174.670.50000111.5I149 V150I149-C176 WeakPolarHBondContact CA-O 2.93Å; V150-C176 PolarHBondContact N-O 3.38Å; V150-C176 PolarHBondContact O-N 3.34Å
177H97Very high94.5Very high68 Ų6853.1 Ų53.132%0.31529%0.285SS..EExtended strand (participates in β ladder)trans-72.8142165.9-65.579.9000109.9H79 Q83 N148H79-H177 AromaticContact CD2-CE1 3.91Å; Q83-H177 PolarHBondContact OE1-CE1 2.8Å; Q83-H177 PolarHBondContact OE1-NE2 2.74Å; N148-H177 CarbonylContact O-C 3.55Å; N148-H177 VanDerWaalsContact O-CA 3.26Å; N148-H177 WeakPolarHBondContact O-CA 3.26Å
178L96.4Very high94.2Very high6 Ų653.5 Ų53.53%0.03129%0.288CS..  trans-140.8104.1176.8-17566.4000108.7N148 V150 E182 L184 K212N148-L178 WeakPolarHBondContact CB-O 3.39Å; N148-L178 PolarHBondContact O-N 2.87Å; V150-L178 HydrophobicContact CG1-CB 4.28Å; L178-E182 HydrophobicContact CD1-CB 3.65Å; L178-E182 HydrophobicContact CG-CB 4.44Å; L178-L184 HydrophobicContact CD1-CD1 4.28Å; L178-L184 HydrophobicContact CD1-CD2 3.92Å; L178-L184 HydrophobicContact CD1-CG 3.73Å; L178-L184 HydrophobicContact CD2-CD1 4.41Å; L178-L184 HydrophobicContact CD2-CG 4.47Å; L178-K212 HydrophobicContact CD2-CG 4.2Å
179E93.9Very high93.8Very high92 Ų9251.8 Ų51.843%0.4329%0.288SS..  trans-68.4153.3-178.9-68.1-59.9145.900111.2N148 G181 E182N148-E179 PolarHBondContact ND2-OE2 2.76Å; E179-G181 PolarHBondContact O-N 3.39Å; E179-G181 VanDerWaalsContact O-N 3.12Å; E179-E182 HydrophobicContact CB-CG 4.05Å; E179-E182 PolarHBondContact N-OE2 2.88Å; E179-E182 WeakPolarHBondContact O-CB 3.42Å; E179-E182 PolarHBondContact O-N 3.5Å
180P90.3Very high93.4Very high102 Ų10252.9 Ų52.966%0.66230%0.295SS*.THydrogen-bonded Turntrans-56.3120.7179.4-25.334.9000112.1
181G88.2Confident93.2Very high81 Ų8153.5 Ų53.584%0.83530%0.298SS*.THydrogen-bonded Turntrans95.1-12.2-179.600000114.6E179E179-G181 PolarHBondContact O-N 3.39Å; E179-G181 VanDerWaalsContact O-N 3.12Å
182E94.6Very high93.2Very high109 Ų10950.9 Ų50.951%0.50929%0.286SS..  trans-75.5155.1170.9-65.9-174.4160.200111.5L178 E179L178-E182 HydrophobicContact CD1-CB 3.65Å; L178-E182 HydrophobicContact CG-CB 4.44Å; E179-E182 HydrophobicContact CB-CG 4.05Å; E179-E182 PolarHBondContact N-OE2 2.88Å; E179-E182 WeakPolarHBondContact O-CB 3.42Å; E179-E182 PolarHBondContact O-N 3.5Å
183K95.6Very high93.4Very high99 Ų9951.6 Ų51.643%0.4329%0.288SS..  trans-134.7144.3177.6-66-66.3-179.5-178.60110.4P208 Y210 E213K183-P208 WeakPolarHBondContact CB-O 3.49Å; K183-Y210 CarbonylContact C-O 3.59Å; K183-Y210 WeakPolarHBondContact CA-O 3.2Å; K183-Y210 WeakPolarHBondContact CD-O 3.31Å; K183-E213 IonicContact NZ-OE1 3.75Å; K183-E213 IonicContact NZ-OE2 3.88Å
184L95.8Very high93.6Very high33 Ų3350.7 Ų50.717%0.17328%0.276CS..BIsolated β-bridgetrans-98.9157.4177.9-59.9172.2000110.4V150 L178 G209 Y210V150-L184 HydrophobicContact CG1-CD1 3.77Å; L178-L184 HydrophobicContact CD1-CD1 4.28Å; L178-L184 HydrophobicContact CD1-CD2 3.92Å; L178-L184 HydrophobicContact CD1-CG 3.73Å; L178-L184 HydrophobicContact CD2-CD1 4.41Å; L178-L184 HydrophobicContact CD2-CG 4.47Å; L184-G209 CarbonylContact O-C 3.55Å; L184-G209 WeakPolarHBondContact O-CA 3.31Å; L184-Y210 HydrophobicContact CB-CD1 4.28Å; L184-Y210 HydrophobicContact CB-CD2 3.99Å; L184-Y210 HydrophobicContact CB-CE1 3.86Å; L184-Y210 HydrophobicContact CB-CE2 3.53Å; L184-Y210 HydrophobicContact CB-CG 4.35Å; L184-Y210 VanDerWaalsContact CB-CZ 3.45Å; L184-Y210 HydrophobicContact CD1-CD2 4.42Å; L184-Y210 HydrophobicContact CD1-CE2 3.71Å; L184-Y210 HydrophobicContact CG-CE2 4.23Å; L184-Y210 PolarHBondContact N-O 2.83Å; L184-Y210 VanDerWaalsContact O-CD1 3.25Å; L184-Y210 WeakPolarHBondContact O-CD1 3.45Å; L184-Y210 PolarHBondContact O-N 2.75Å
185R94.8Very high93.9Very high110 Ų11047.5 Ų47.542%0.41526%0.263SS..  trans-131.7-14.5177.4-55.2-173.372.898.610.8114L187 C201 D204 E205 H207R185-L187 PolarHBondContact O-N 3.04Å; R185-C201 PolarHBondContact NH2-O 3.12Å; R185-D204 PolarHBondContact NH2-O 3.44Å; R185-E205 PolarHBondContact NH1-O 2.84Å; R185-E205 VanDerWaalsContact NH2-C 3.3Å; R185-E205 PolarHBondContact NH2-O 2.83Å; R185-H207 PolarHBondContact NH1-O 3.18Å; R185-H207 PolarHBondContact NH2-O 2.94Å
186E92.6Very high94Very high107 Ų10747.4 Ų47.450%0.526%0.262SS..  trans-60.6126.4-177.8-175.1-172.4-177.100110.9R152 C188 Y210R152-E186 IonicContact CZ-OE2 3.41Å; R152-E186 IonicContact NH1-OE2 2.75Å; R152-E186 PolarHBondContact NH1-OE2 3.34Å; R152-E186 IonicContact NH2-OE2 3.16Å; R152-E186 PolarHBondContact NH2-OE2 2.94Å; R152-E186 VanDerWaalsContact NH2-OE2 3.16Å; E186-C188 HydrophobicContact CG-CB 4.38Å; E186-C188 PolarHBondContact O-N 3.35Å; E186-Y210 WeakPolarHBondContact O-CE1 3.28Å; E186-Y210 PolarHBondContact O-OH 2.88Å
187L93.1Very high94.1Very high58 Ų5846.8 Ų46.830%0.30426%0.257SS..  trans-81.1101.4172.2178.663.6000109.2R185 L194 I198 L199 I396R185-L187 PolarHBondContact O-N 3.04Å; L187-L194 HydrophobicContact CD1-CD1 3.95Å; L187-I198 HydrophobicContact CD1-CG2 3.64Å; L187-L199 HydrophobicContact CD1-CD2 4.35Å; L187-I396 HydrophobicContact CD2-CD1 3.6Å; L187-I396 HydrophobicContact CG-CD1 4.46Å
188C90.9Very high94Very high10 Ų1043.7 Ų43.77%0.06824%0.243CC..  trans-141.2161.6177.462.20000111R152 F174 E186 L194R152-C188 VanDerWaalsContact CZ-SG 3.54Å; R152-C188 PolarHBondContact NH1-SG 2.87Å; F174-C188 HydrophobicContact CD1-CB 3.69Å; F174-C188 HydrophobicContact CE1-CB 3.99Å; F174-C188 HydrophobicContact CG-CB 4.46Å; E186-C188 HydrophobicContact CG-CB 4.38Å; E186-C188 PolarHBondContact O-N 3.35Å; C188-L194 WeakPolarHBondContact O-CD2 3.09Å
189G90.9Very high93.9Very high20 Ų2043.7 Ų43.721%0.20624%0.243CC..SBendtrans98174.2-178.400000114D153D153-G189 WeakPolarHBondContact OD1-CA 3.39Å
190T89.7Confident93.8Very high23 Ų2342.7 Ų42.714%0.14124%0.237CC..  trans-81125.1-170.9-56.10000111.9D153 K155 G192 Y193 L194D153-T190 WeakPolarHBondContact OD1-CB 3.41Å; D153-T190 PolarHBondContact OD1-N 3.1Å; D153-T190 PolarHBondContact OD1-OG1 3.16Å; K155-T190 HydrophobicContact CD-CG2 4.37Å; K155-T190 VanDerWaalsContact CD-OG1 3.25Å; K155-T190 WeakPolarHBondContact CD-OG1 3.32Å; K155-T190 PolarHBondContact NZ-OG1 3.05Å; T190-G192 VanDerWaalsContact C-N 3.29Å; T190-G192 PolarHBondContact O-N 3.43Å; T190-Y193 HydrophobicContact CG2-CD2 3.96Å; T190-Y193 HydrophobicContact CG2-CE2 4.32Å; T190-Y193 PolarHBondContact O-N 2.86Å; T190-L194 PolarHBondContact O-N 3.24Å
191P90.9Very high93.9Very high28 Ų2838.1 Ų38.118%0.18221%0.208CC..G310 helixtrans-49.3-36.7-170.2-33.736.3000117.2Y193 M241 L242 I245P191-Y193 PolarHBondContact O-N 3.15Å; P191-M241 HydrophobicContact CB-CE 3.75Å; P191-L242 HydrophobicContact CB-CD2 4.49Å; P191-I245 VanDerWaalsContact O-CD1 3.25Å; P191-I245 WeakPolarHBondContact O-CD1 3.46Å
192G93Very high94Very high5 Ų537 Ų375%0.05219%0.186CC..G310 helixtrans-72.4-12-179.800000115.2T190T190-G192 VanDerWaalsContact C-N 3.29Å; T190-G192 PolarHBondContact O-N 3.43Å
193Y97.3Very high93.6Very high15 Ų1535 Ų356%0.05918%0.178CC..G310 helixtrans-115.7-2.7-178.1-59.2-89.3000112.4K155 P156 T190 P191 V221 I222K155-Y193 HydrophobicContact CB-CD1 4.27Å; K155-Y193 HydrophobicContact CB-CD2 3.82Å; K155-Y193 HydrophobicContact CB-CE1 4.16Å; K155-Y193 HydrophobicContact CB-CE2 3.66Å; K155-Y193 HydrophobicContact CB-CG 4.13Å; P156-Y193 VanDerWaalsContact CD-CZ 3.44Å; P156-Y193 WeakPolarHBondContact CD-OH 3.44Å; T190-Y193 HydrophobicContact CG2-CD2 3.96Å; T190-Y193 HydrophobicContact CG2-CE2 4.32Å; T190-Y193 PolarHBondContact O-N 2.86Å; P191-Y193 PolarHBondContact O-N 3.15Å; Y193-V221 HydrophobicContact CD1-CB 3.82Å; Y193-V221 HydrophobicContact CD1-CG1 3.4Å; Y193-V221 VanDerWaalsContact CD1-CG1 3.4Å; Y193-V221 HydrophobicContact CE1-CB 4.25Å; Y193-V221 HydrophobicContact CE1-CG1 3.51Å; Y193-V221 HydrophobicContact CG-CG1 4.25Å; Y193-I222 HydrophobicContact CD1-CG1 4.25Å; Y193-I222 HydrophobicContact CE1-CG1 3.98Å
194L97.1Very high93.3Very high11 Ų1133.8 Ų33.86%0.05818%0.176CC..  trans-64.2138.1178-65.1179.9000111.2L187 C188 T190 I198 L199 W217 I245L187-L194 HydrophobicContact CD1-CD1 3.95Å; C188-L194 WeakPolarHBondContact O-CD2 3.09Å; T190-L194 PolarHBondContact O-N 3.24Å; L194-I198 HydrophobicContact CD2-CD1 4.09Å; L194-I198 HydrophobicContact CD2-CG2 4.44Å; L194-L199 HydrophobicContact CB-CD2 4.38Å; L194-L199 HydrophobicContact CD1-CD2 3.8Å; L194-W217 PolarHBondContact O-NE1 2.83Å; L194-I245 VanDerWaalsContact O-CG2 3.22Å; L194-I245 WeakPolarHBondContact O-CG2 3.48Å
195A97.9Very high92.9Very high1 Ų140.6 Ų40.61%0.00821%0.207CC..  trans-78.5152.5174.600000111.6E197 I198 L199 V214 W217A195-E197 VanDerWaalsContact C-N 3.26Å; A195-E197 HydrophobicContact CB-CG 4.38Å; A195-E197 WeakPolarHBondContact CB-OE1 3.3Å; A195-E197 WeakPolarHBondContact CB-OE2 3.48Å; A195-E197 PolarHBondContact O-N 2.9Å; A195-I198 HydrophobicContact CB-CD1 4.35Å; A195-I198 HydrophobicContact CB-CG1 4.35Å; A195-I198 PolarHBondContact O-N 2.81Å; A195-I198 VanDerWaalsContact O-N 3.14Å; A195-L199 PolarHBondContact O-N 2.9Å; A195-V214 HydrophobicContact CB-CB 3.99Å; A195-V214 HydrophobicContact CB-CG1 3.93Å; A195-W217 HydrophobicContact CB-CB 3.77Å; A195-W217 HydrophobicContact CB-CD2 4.39Å; A195-W217 HydrophobicContact CB-CG 3.78Å
196P97.8Very high92.8Very high0 Ų041.2 Ų41.20%022%0.223CC..Hα-helixtrans-55-38.9-179.2-28.437.2000113.8I198 L199 K200 W217 I245 V274P196-I198 VanDerWaalsContact C-N 3.35Å; P196-I198 PolarHBondContact O-N 2.87Å; P196-L199 PolarHBondContact O-N 2.82Å; P196-K200 VanDerWaalsContact O-CG 3.31Å; P196-K200 WeakPolarHBondContact O-CG 3.33Å; P196-K200 PolarHBondContact O-N 2.95Å; P196-W217 HydrophobicContact CG-CD2 4.44Å; P196-W217 HydrophobicContact CG-CE3 4.12Å; P196-W217 HydrophobicContact CG-CH2 3.49Å; P196-W217 VanDerWaalsContact CG-CH2 3.49Å; P196-W217 HydrophobicContact CG-CZ2 3.85Å; P196-W217 HydrophobicContact CG-CZ3 3.64Å; P196-I245 HydrophobicContact CG-CG2 4.29Å; P196-I245 WeakPolarHBondContact CG-O 3.29Å; P196-V274 HydrophobicContact CB-CG1 4.02Å; P196-V274 HydrophobicContact CG-CB 4.48Å; P196-V274 HydrophobicContact CG-CG1 4.18Å; P196-V274 HydrophobicContact CG-CG2 4.38Å
197E97.5Very high92.8Very high4 Ų438 Ų382%0.01921%0.208CC..Hα-helixtrans-68.6-28-178.761.9-87-15900113.8A195 C201 V214 R279A195-E197 VanDerWaalsContact C-N 3.26Å; A195-E197 HydrophobicContact CB-CG 4.38Å; A195-E197 WeakPolarHBondContact CB-OE1 3.3Å; A195-E197 WeakPolarHBondContact CB-OE2 3.48Å; A195-E197 PolarHBondContact O-N 2.9Å; E197-C201 WeakPolarHBondContact O-CB 3.49Å; E197-C201 PolarHBondContact O-N 2.97Å; E197-C201 PolarHBondContact O-SG 2.98Å; E197-C201 VanDerWaalsContact O-SG 3.4Å; E197-V214 HydrophobicContact CG-CG1 4.13Å; E197-R279 IonicContact OE1-CZ 3.7Å; E197-R279 IonicContact OE1-NH1 3.67Å; E197-R279 PolarHBondContact OE1-NH1 2.9Å; E197-R279 IonicContact OE1-NH2 3.37Å; E197-R279 PolarHBondContact OE1-NH2 2.99Å; E197-R279 IonicContact OE2-CZ 3.36Å; E197-R279 IonicContact OE2-NH1 2.71Å; E197-R279 IonicContact OE2-NH2 2.97Å; E197-R279 PolarHBondContact OE2-NH2 3.22Å
198I96.2Very high92.8Very high3 Ų340 Ų402%0.01522%0.224CC..Hα-helixtrans-66.3-44.7172.1-58.7176.8000109.2L187 L194 A195 P196 C201 S202 Y210 V214L187-I198 HydrophobicContact CD1-CG2 3.64Å; L194-I198 HydrophobicContact CD2-CD1 4.09Å; L194-I198 HydrophobicContact CD2-CG2 4.44Å; A195-I198 HydrophobicContact CB-CD1 4.35Å; A195-I198 HydrophobicContact CB-CG1 4.35Å; A195-I198 PolarHBondContact O-N 2.81Å; A195-I198 VanDerWaalsContact O-N 3.14Å; P196-I198 VanDerWaalsContact C-N 3.35Å; P196-I198 PolarHBondContact O-N 2.87Å; I198-C201 PolarHBondContact O-SG 3.4Å; I198-S202 PolarHBondContact O-N 2.71Å; I198-Y210 HydrophobicContact CB-CD1 4.32Å; I198-Y210 HydrophobicContact CB-CE1 4.48Å; I198-Y210 HydrophobicContact CG1-CD1 3.81Å; I198-Y210 HydrophobicContact CG1-CD2 4.15Å; I198-Y210 HydrophobicContact CG1-CE1 4.06Å; I198-Y210 HydrophobicContact CG1-CE2 4.38Å; I198-Y210 HydrophobicContact CG1-CG 3.86Å; I198-Y210 HydrophobicContact CG2-CD1 4.5Å; I198-Y210 HydrophobicContact CG2-CE1 4.19Å; I198-V214 HydrophobicContact CD1-CB 3.91Å; I198-V214 HydrophobicContact CD1-CG1 3.78Å; I198-V214 HydrophobicContact CD1-CG2 4.4Å; I198-V214 HydrophobicContact CG1-CB 4.38Å; I198-V214 HydrophobicContact CG1-CG1 3.69Å
199L94Very high93Very high6 Ų639.8 Ų39.83%0.03122%0.224CC..Hα-helixtrans-66.7-44.2178.7-58.3178.8000111.1L187 L194 A195 P196 S202 M203 L242 I245 M246L187-L199 HydrophobicContact CD1-CD2 4.35Å; L194-L199 HydrophobicContact CB-CD2 4.38Å; L194-L199 HydrophobicContact CD1-CD2 3.8Å; A195-L199 PolarHBondContact O-N 2.9Å; P196-L199 PolarHBondContact O-N 2.82Å; L199-S202 PolarHBondContact O-N 2.98Å; L199-M203 HydrophobicContact CB-CE 4.39Å; L199-M203 VanDerWaalsContact O-CG 3.29Å; L199-M203 WeakPolarHBondContact O-CG 3.37Å; L199-M203 PolarHBondContact O-N 3.38Å; L199-L242 HydrophobicContact CD1-CB 4.19Å; L199-L242 HydrophobicContact CD1-CD2 3.99Å; L199-L242 HydrophobicContact CD2-CD2 3.95Å; L199-I245 HydrophobicContact CD1-CB 4.06Å; L199-I245 HydrophobicContact CD1-CG2 3.69Å; L199-M246 HydrophobicContact CB-CG 3.95Å; L199-M246 HydrophobicContact CB-SD 4.27Å; L199-M246 HydrophobicContact CD1-CG 3.77Å
200K92.5Very high93.3Very high72 Ų7239 Ų3931%0.31322%0.215SC..Hα-helixtrans-61.8-45.4177.9-72170.6-177.4175.30111.8P196 S202 M203 D204 M246P196-K200 VanDerWaalsContact O-CG 3.31Å; P196-K200 WeakPolarHBondContact O-CG 3.33Å; P196-K200 PolarHBondContact O-N 2.95Å; K200-S202 VanDerWaalsContact C-N 3.27Å; K200-S202 PolarHBondContact O-N 2.94Å; K200-M203 PolarHBondContact O-N 3.47Å; K200-M203 VanDerWaalsContact O-N 3.14Å; K200-D204 PolarHBondContact O-N 2.82Å; K200-M246 HydrophobicContact CG-CE 4.17Å
201C92.1Very high93.7Very high6 Ų637.9 Ų37.94%0.04121%0.209CC..Hα-helixtrans-70.3-24.1-178.376.80000114.2R185 E197 I198 M203 H207R185-C201 PolarHBondContact NH2-O 3.12Å; E197-C201 WeakPolarHBondContact O-CB 3.49Å; E197-C201 PolarHBondContact O-N 2.97Å; E197-C201 PolarHBondContact O-SG 2.98Å; E197-C201 VanDerWaalsContact O-SG 3.4Å; I198-C201 PolarHBondContact O-SG 3.4Å; C201-M203 VanDerWaalsContact C-N 3.34Å; C201-H207 HydrophobicContact CB-CB 4.09Å
202S89.5Confident94Very high56 Ų5638.6 Ų38.639%0.39221%0.209SC..Hα-helixtrans-76.9-20.8173.1-175.90000112.9I198 L199 K200I198-S202 PolarHBondContact O-N 2.71Å; L199-S202 PolarHBondContact O-N 2.98Å; K200-S202 VanDerWaalsContact C-N 3.27Å; K200-S202 PolarHBondContact O-N 2.94Å
203M86.6Confident94.3Very high68 Ų6841.2 Ų41.234%0.33522%0.22SC..Hα-helixtrans-102-27.6-179.1-64.4174.7-168.400112.9L199 K200 C201 M246 A401 V404L199-M203 HydrophobicContact CB-CE 4.39Å; L199-M203 VanDerWaalsContact O-CG 3.29Å; L199-M203 WeakPolarHBondContact O-CG 3.37Å; L199-M203 PolarHBondContact O-N 3.38Å; K200-M203 PolarHBondContact O-N 3.47Å; K200-M203 VanDerWaalsContact O-N 3.14Å; C201-M203 VanDerWaalsContact C-N 3.34Å; M203-M246 HydrophobicContact CE-SD 4Å; M203-M246 HydrophobicContact SD-CE 3.85Å; M203-M246 HydrophobicContact SD-SD 3.95Å; M203-A401 HydrophobicContact CG-CB 4.28Å; M203-V404 HydrophobicContact CE-CG1 4.46Å; M203-V404 HydrophobicContact CE-CG2 3.82Å; M203-V404 HydrophobicContact SD-CB 4.39Å; M203-V404 HydrophobicContact SD-CG1 4.35Å; M203-V404 HydrophobicContact SD-CG2 4.29Å
204D88.6Confident94.3Very high73 Ų7340.7 Ų40.739%0.3922%0.218SC..  trans-122.9107.2-178.3179.83.8000110.1R185 K200 T206 H207R185-D204 PolarHBondContact NH2-O 3.44Å; K200-D204 PolarHBondContact O-N 2.82Å; D204-T206 VanDerWaalsContact CG-OG1 3.25Å; D204-T206 PolarHBondContact O-N 3.35Å; D204-T206 WeakPolarHBondContact OD1-CA 3.42Å; D204-T206 WeakPolarHBondContact OD1-CB 3.39Å; D204-T206 PolarHBondContact OD1-N 3.31Å; D204-T206 PolarHBondContact OD1-OG1 3.44Å; D204-T206 PolarHBondContact OD2-OG1 3.04Å; D204-H207 HydrophobicContact CB-CB 4.39Å; D204-H207 VanDerWaalsContact O-CB 3.3Å; D204-H207 WeakPolarHBondContact O-CB 3.28Å; D204-H207 PolarHBondContact O-N 3.07Å; D204-H207 VanDerWaalsContact O-N 3.11Å
205E88Confident94.4Very high177 Ų17740.2 Ų40.283%0.82722%0.216SC*.THydrogen-bonded Turntrans-59.7-25.6177.3-67.7-172.617200112.6R185 H207R185-E205 PolarHBondContact NH1-O 2.84Å; R185-E205 VanDerWaalsContact NH2-C 3.3Å; R185-E205 PolarHBondContact NH2-O 2.83Å; E205-H207 VanDerWaalsContact C-N 3.32Å; E205-H207 PolarHBondContact O-N 3.22Å
206T92.3Very high94.5Very high122 Ų12240.3 Ų40.375%0.74822%0.216SC*.THydrogen-bonded Turntrans-79.4-14.3-18073.70000113.5D204D204-T206 VanDerWaalsContact CG-OG1 3.25Å; D204-T206 PolarHBondContact O-N 3.35Å; D204-T206 WeakPolarHBondContact OD1-CA 3.42Å; D204-T206 WeakPolarHBondContact OD1-CB 3.39Å; D204-T206 PolarHBondContact OD1-N 3.31Å; D204-T206 PolarHBondContact OD1-OG1 3.44Å; D204-T206 PolarHBondContact OD2-OG1 3.04Å
207H93.7Very high94.5Very high40 Ų4040.3 Ų40.319%0.18522%0.216CC..SBendtrans-62.4140.1176.7-166.9-87.6000110.5R185 C201 D204 E205 G209R185-H207 PolarHBondContact NH1-O 3.18Å; R185-H207 PolarHBondContact NH2-O 2.94Å; C201-H207 HydrophobicContact CB-CB 4.09Å; D204-H207 HydrophobicContact CB-CB 4.39Å; D204-H207 VanDerWaalsContact O-CB 3.3Å; D204-H207 WeakPolarHBondContact O-CB 3.28Å; D204-H207 PolarHBondContact O-N 3.07Å; D204-H207 VanDerWaalsContact O-N 3.11Å; E205-H207 VanDerWaalsContact C-N 3.32Å; E205-H207 PolarHBondContact O-N 3.22Å; H207-G209 PolarHBondContact CE1-O 2.84Å; H207-G209 PolarHBondContact ND1-N 2.7Å; H207-G209 PolarHBondContact ND1-O 3.47Å; H207-G209 PolarHBondContact O-N 2.8Å; H207-G209 VanDerWaalsContact O-N 3.09Å
208P92.1Very high94.6Very high99 Ų9940.4 Ų40.464%0.64322%0.217SC*.  trans-69-8.5-175.726.9-36.4000115K183K183-P208 WeakPolarHBondContact CB-O 3.49Å
209G95.6Very high94.7Very high6 Ų640.2 Ų40.26%0.06222%0.216CC..  trans96.6-166.9-174.100000113.2L184 H207L184-G209 CarbonylContact O-C 3.55Å; L184-G209 WeakPolarHBondContact O-CA 3.31Å; H207-G209 PolarHBondContact CE1-O 2.84Å; H207-G209 PolarHBondContact ND1-N 2.7Å; H207-G209 PolarHBondContact ND1-O 3.47Å; H207-G209 PolarHBondContact O-N 2.8Å; H207-G209 VanDerWaalsContact O-N 3.09Å
210Y97.2Very high94.9Very high3 Ų340 Ų401%0.01222%0.215CC..BIsolated β-bridgetrans-126.8164.7-17866.6-95000111.9R152 K183 L184 E186 I198 V214R152-Y210 PolarHBondContact NH1-OH 3.09Å; K183-Y210 CarbonylContact C-O 3.59Å; K183-Y210 WeakPolarHBondContact CA-O 3.2Å; K183-Y210 WeakPolarHBondContact CD-O 3.31Å; L184-Y210 HydrophobicContact CB-CD1 4.28Å; L184-Y210 HydrophobicContact CB-CD2 3.99Å; L184-Y210 HydrophobicContact CB-CE1 3.86Å; L184-Y210 HydrophobicContact CB-CE2 3.53Å; L184-Y210 HydrophobicContact CB-CG 4.35Å; L184-Y210 VanDerWaalsContact CB-CZ 3.45Å; L184-Y210 HydrophobicContact CD1-CD2 4.42Å; L184-Y210 HydrophobicContact CD1-CE2 3.71Å; L184-Y210 HydrophobicContact CG-CE2 4.23Å; L184-Y210 PolarHBondContact N-O 2.83Å; L184-Y210 VanDerWaalsContact O-CD1 3.25Å; L184-Y210 WeakPolarHBondContact O-CD1 3.45Å; L184-Y210 PolarHBondContact O-N 2.75Å; E186-Y210 WeakPolarHBondContact O-CE1 3.28Å; E186-Y210 PolarHBondContact O-OH 2.88Å; I198-Y210 HydrophobicContact CB-CD1 4.32Å; I198-Y210 HydrophobicContact CB-CE1 4.48Å; I198-Y210 HydrophobicContact CG1-CD1 3.81Å; I198-Y210 HydrophobicContact CG1-CD2 4.15Å; I198-Y210 HydrophobicContact CG1-CE1 4.06Å; I198-Y210 HydrophobicContact CG1-CE2 4.38Å; I198-Y210 HydrophobicContact CG1-CG 3.86Å; I198-Y210 HydrophobicContact CG2-CD1 4.5Å; I198-Y210 HydrophobicContact CG2-CE1 4.19Å; Y210-V214 HydrophobicContact CD2-CG1 3.53Å; Y210-V214 HydrophobicContact CD2-CG2 4.2Å; Y210-V214 HydrophobicContact CE2-CG1 4.39Å; Y210-V214 HydrophobicContact CE2-CG2 4.44Å; Y210-V214 HydrophobicContact CG-CG1 3.9Å
211G97.6Very high95.2Very high1 Ų136.5 Ų36.51%0.0120%0.2CC..  trans-133.1-146.9178.400000113.1E213 V214G211-E213 WeakPolarHBondContact CA-OE2 3.34Å; G211-E213 PolarHBondContact N-OE2 2.82Å; G211-E213 PolarHBondContact O-N 3.16Å; G211-V214 WeakPolarHBondContact O-CG2 3.43Å
212K98Very high95.6Very high42 Ų4236.2 Ų36.218%0.18320%0.198CC..THydrogen-bonded Turntrans-65.3-20.1-177.2-60.6178.3-176.1172.30112.6H145 N148 V150 L178 V214 D215H145-K212 HydrophobicContact CB-CD 3.98Å; H145-K212 PolarHBondContact CE1-O 3.41Å; H145-K212 PolarHBondContact NE2-O 3.04Å; H145-K212 PolarHBondContact O-NZ 3.37Å; N148-K212 PolarHBondContact OD1-NZ 2.84Å; V150-K212 HydrophobicContact CB-CG 4.5Å; L178-K212 HydrophobicContact CD2-CG 4.2Å; K212-V214 PolarHBondContact O-N 2.95Å; K212-V214 VanDerWaalsContact O-N 3.12Å; K212-D215 PolarHBondContact O-N 2.98Å
213E98.4Very high96Very high60 Ų6033.6 Ų33.628%0.2818%0.179SC..Hα-helixtrans-63.1-21.6-174.7-50.579.9-170.200112.7K183 G211 D215 L216 W217 P276 R279K183-E213 IonicContact NZ-OE1 3.75Å; K183-E213 IonicContact NZ-OE2 3.88Å; G211-E213 WeakPolarHBondContact CA-OE2 3.34Å; G211-E213 PolarHBondContact N-OE2 2.82Å; G211-E213 PolarHBondContact O-N 3.16Å; E213-D215 VanDerWaalsContact C-N 3.29Å; E213-D215 PolarHBondContact O-N 3.33Å; E213-L216 PolarHBondContact O-N 3.07Å; E213-L216 VanDerWaalsContact O-N 3.13Å; E213-W217 PolarHBondContact O-N 2.99Å; E213-P276 HydrophobicContact CB-CB 3.88Å; E213-P276 HydrophobicContact CG-CB 4.1Å; E213-R279 PolarHBondContact O-NH1 2.96Å
214V98.6Very high96.6Very high5 Ų530.7 Ų30.73%0.0317%0.165CC..Hα-helixtrans-63.8-33.6178.8-56.30000112.7V150 A195 E197 I198 Y210 G211 K212 L216 W217 A218V150-V214 HydrophobicContact CG2-CG2 3.95Å; A195-V214 HydrophobicContact CB-CB 3.99Å; A195-V214 HydrophobicContact CB-CG1 3.93Å; E197-V214 HydrophobicContact CG-CG1 4.13Å; I198-V214 HydrophobicContact CD1-CB 3.91Å; I198-V214 HydrophobicContact CD1-CG1 3.78Å; I198-V214 HydrophobicContact CD1-CG2 4.4Å; I198-V214 HydrophobicContact CG1-CB 4.38Å; I198-V214 HydrophobicContact CG1-CG1 3.69Å; Y210-V214 HydrophobicContact CD2-CG1 3.53Å; Y210-V214 HydrophobicContact CD2-CG2 4.2Å; Y210-V214 HydrophobicContact CE2-CG1 4.39Å; Y210-V214 HydrophobicContact CE2-CG2 4.44Å; Y210-V214 HydrophobicContact CG-CG1 3.9Å; G211-V214 WeakPolarHBondContact O-CG2 3.43Å; K212-V214 PolarHBondContact O-N 2.95Å; K212-V214 VanDerWaalsContact O-N 3.12Å; V214-L216 PolarHBondContact O-N 3.28Å; V214-W217 WeakPolarHBondContact O-CB 3.39Å; V214-W217 PolarHBondContact O-N 3.03Å; V214-A218 PolarHBondContact O-N 3.46Å; V214-A218 VanDerWaalsContact O-N 3.15Å
215D98.8Very high97Very high1 Ų127.5 Ų27.51%0.00515%0.148CC..Hα-helixtrans-66.2-30.2176.9-74.3-20.2000111V141 H145 V150 H151 R152 L154 K212 E213 A218 C219V141-D215 HydrophobicContact CG1-CB 4.12Å; H145-D215 IonicContact CD2-OD2 3.46Å; H145-D215 IonicContact CE1-OD2 3.84Å; H145-D215 IonicContact NE2-OD2 3.43Å; H145-D215 PolarHBondContact NE2-OD2 3.05Å; V150-D215 WeakPolarHBondContact CG2-OD2 3.45Å; H151-D215 PolarHBondContact N-OD1 3.36Å; H151-D215 PolarHBondContact N-OD2 3.28Å; R152-D215 PolarHBondContact N-OD1 2.95Å; L154-D215 HydrophobicContact CD1-CB 3.61Å; L154-D215 WeakPolarHBondContact CD1-O 3.3Å; K212-D215 PolarHBondContact O-N 2.98Å; E213-D215 VanDerWaalsContact C-N 3.29Å; E213-D215 PolarHBondContact O-N 3.33Å; D215-A218 PolarHBondContact O-N 2.89Å; D215-C219 PolarHBondContact O-N 2.67Å; D215-C219 PolarHBondContact O-SG 3.35Å
216L98.9Very high97.5Very high3 Ų319 Ų192%0.01611%0.109CC..Hα-helixtrans-77.4-33.1179.9-75.9-58.9000111.9L138 V141 H145 E213 V214 C219 G220 L271 R279 L280 A282L138-L216 HydrophobicContact CD2-CD1 3.77Å; V141-L216 HydrophobicContact CG1-CD2 4.09Å; H145-L216 WeakPolarHBondContact CE1-CD2 3.48Å; E213-L216 PolarHBondContact O-N 3.07Å; E213-L216 VanDerWaalsContact O-N 3.13Å; V214-L216 PolarHBondContact O-N 3.28Å; L216-C219 WeakPolarHBondContact O-CB 3.39Å; L216-C219 PolarHBondContact O-N 3.3Å; L216-G220 PolarHBondContact O-N 3.21Å; L216-L271 HydrophobicContact CB-CD2 4.21Å; L216-L271 HydrophobicContact CD1-CD2 4.06Å; L216-R279 HydrophobicContact CB-CG 4.44Å; L216-L280 VanDerWaalsContact CG-O 3.29Å; L216-L280 WeakPolarHBondContact CG-O 3.46Å; L216-A282 HydrophobicContact CD1-CB 4.02Å
217W98.9Very high97.7Very high0 Ų013.3 Ų13.30%07%0.074CC..Hα-helixtrans-59.9-49.6167.8176.9-89.8000110.7L194 A195 P196 E213 V214 C219 G220 V221 F233 I245 L272 V274L194-W217 PolarHBondContact O-NE1 2.83Å; A195-W217 HydrophobicContact CB-CB 3.77Å; A195-W217 HydrophobicContact CB-CD2 4.39Å; A195-W217 HydrophobicContact CB-CG 3.78Å; P196-W217 HydrophobicContact CG-CD2 4.44Å; P196-W217 HydrophobicContact CG-CE3 4.12Å; P196-W217 HydrophobicContact CG-CH2 3.49Å; P196-W217 VanDerWaalsContact CG-CH2 3.49Å; P196-W217 HydrophobicContact CG-CZ2 3.85Å; P196-W217 HydrophobicContact CG-CZ3 3.64Å; E213-W217 PolarHBondContact O-N 2.99Å; V214-W217 WeakPolarHBondContact O-CB 3.39Å; V214-W217 PolarHBondContact O-N 3.03Å; W217-C219 VanDerWaalsContact C-N 3.31Å; W217-C219 PolarHBondContact O-N 3.48Å; W217-G220 WeakPolarHBondContact O-CA 3.25Å; W217-G220 PolarHBondContact O-N 3.39Å; W217-V221 PolarHBondContact O-N 3.01Å; W217-F233 AromaticContact CE2-CE2 3.97Å; W217-F233 HydrophobicContact CH2-CE2 4.1Å; W217-F233 AromaticContact CH2-CZ 3.73Å; W217-F233 HydrophobicContact CH2-CZ 3.73Å; W217-F233 HydrophobicContact CZ2-CD2 4.29Å; W217-F233 HydrophobicContact CZ2-CE1 4.45Å; W217-F233 AromaticContact CZ2-CE2 3.34Å; W217-F233 HydrophobicContact CZ2-CE2 3.34Å; W217-F233 AromaticContact CZ2-CZ 3.44Å; W217-F233 HydrophobicContact CZ2-CZ 3.44Å; W217-F233 VanDerWaalsContact CZ2-CZ 3.44Å; W217-I245 HydrophobicContact CZ2-CG2 3.91Å; W217-L272 HydrophobicContact CD2-CD2 3.94Å; W217-L272 HydrophobicContact CE3-CD2 4.12Å; W217-L272 HydrophobicContact CG-CD2 4.41Å; W217-L272 HydrophobicContact CZ2-CD2 4.39Å; W217-L272 HydrophobicContact CZ3-CB 4.27Å; W217-L272 HydrophobicContact CZ3-CD2 4.43Å; W217-V274 HydrophobicContact CZ3-CG2 4.45Å
218A98.8Very high97.6Very high5 Ų512 Ų124%0.0417%0.069CC..Hα-helixtrans-60.2-39.7177.700000112L154 V214 D215 G220 V221 I222L154-A218 HydrophobicContact CB-CB 3.75Å; V214-A218 PolarHBondContact O-N 3.46Å; V214-A218 VanDerWaalsContact O-N 3.15Å; D215-A218 PolarHBondContact O-N 2.89Å; A218-G220 VanDerWaalsContact C-N 3.29Å; A218-G220 PolarHBondContact O-N 3.46Å; A218-V221 PolarHBondContact O-N 3.45Å; A218-V221 VanDerWaalsContact O-N 3.16Å; A218-I222 VanDerWaalsContact O-CG1 3.28Å; A218-I222 WeakPolarHBondContact O-CG1 3.42Å; A218-I222 PolarHBondContact O-N 3.45Å
219C98.9Very high97.6Very high0 Ų07.5 Ų7.50%04%0.041CC..Hα-helixtrans-58.3-39.2170.4-71.70000112.6M134 L138 D215 L216 W217 I222 L223M134-C219 HydrophobicContact CE-CB 4.11Å; M134-C219 WeakPolarHBondContact CE-O 3.49Å; L138-C219 HydrophobicContact CD2-CB 4.24Å; D215-C219 PolarHBondContact O-N 2.67Å; D215-C219 PolarHBondContact O-SG 3.35Å; L216-C219 WeakPolarHBondContact O-CB 3.39Å; L216-C219 PolarHBondContact O-N 3.3Å; W217-C219 VanDerWaalsContact C-N 3.31Å; W217-C219 PolarHBondContact O-N 3.48Å; C219-I222 PolarHBondContact O-N 2.75Å; C219-L223 VanDerWaalsContact O-CB 3.32Å; C219-L223 WeakPolarHBondContact O-CB 3.44Å; C219-L223 PolarHBondContact O-N 3.48Å
220G98.8Very high97.3Very high0 Ų09.4 Ų9.40%05%0.053CC..Hα-helixtrans-62.3-43.6173.100000112.9L216 W217 A218 L223 F224L216-G220 PolarHBondContact O-N 3.21Å; W217-G220 WeakPolarHBondContact O-CA 3.25Å; W217-G220 PolarHBondContact O-N 3.39Å; A218-G220 VanDerWaalsContact C-N 3.29Å; A218-G220 PolarHBondContact O-N 3.46Å; G220-L223 PolarHBondContact O-N 2.86Å; G220-F224 WeakPolarHBondContact O-CB 3.23Å; G220-F224 PolarHBondContact O-N 2.94Å
221V98.8Very high97.2Very high0 Ų09.8 Ų9.80%06%0.056CC..Hα-helixtrans-63.7-44.1176.41780000110.8Y193 W217 A218 F224 T225 P232 F233 L272Y193-V221 HydrophobicContact CD1-CB 3.82Å; Y193-V221 HydrophobicContact CD1-CG1 3.4Å; Y193-V221 VanDerWaalsContact CD1-CG1 3.4Å; Y193-V221 HydrophobicContact CE1-CB 4.25Å; Y193-V221 HydrophobicContact CE1-CG1 3.51Å; Y193-V221 HydrophobicContact CG-CG1 4.25Å; W217-V221 PolarHBondContact O-N 3.01Å; A218-V221 PolarHBondContact O-N 3.45Å; A218-V221 VanDerWaalsContact O-N 3.16Å; V221-F224 PolarHBondContact O-N 3.38Å; V221-T225 VanDerWaalsContact O-CB 3.29Å; V221-T225 WeakPolarHBondContact O-CB 3.32Å; V221-T225 PolarHBondContact O-N 2.82Å; V221-T225 PolarHBondContact O-OG1 3.48Å; V221-P232 HydrophobicContact CB-CG 4.36Å; V221-P232 HydrophobicContact CG1-CG 4.02Å; V221-P232 HydrophobicContact CG2-CG 4.22Å; V221-F233 HydrophobicContact CG2-CD2 4.41Å; V221-F233 HydrophobicContact CG2-CE2 4.14Å; V221-L272 HydrophobicContact CG2-CD2 3.78Å
222I98.8Very high97.1Very high0 Ų010.3 Ų10.30%06%0.06CC..Hα-helixtrans-61.2-51.2175.5-67.1162.5000110.1M134 L137 L154 P156 I159 Y193 A218 C219 F224 T225 L226M134-I222 HydrophobicContact SD-CG2 3.93Å; L137-I222 HydrophobicContact CD2-CD1 3.99Å; L137-I222 HydrophobicContact CD2-CG2 4.29Å; L154-I222 HydrophobicContact CB-CD1 4.17Å; P156-I222 HydrophobicContact CG-CG1 4.36Å; I159-I222 HydrophobicContact CD1-CD1 4.04Å; I159-I222 HydrophobicContact CD1-CG2 4.45Å; Y193-I222 HydrophobicContact CD1-CG1 4.25Å; Y193-I222 HydrophobicContact CE1-CG1 3.98Å; A218-I222 VanDerWaalsContact O-CG1 3.28Å; A218-I222 WeakPolarHBondContact O-CG1 3.42Å; A218-I222 PolarHBondContact O-N 3.45Å; C219-I222 PolarHBondContact O-N 2.75Å; I222-F224 VanDerWaalsContact C-N 3.31Å; I222-F224 PolarHBondContact O-N 3.14Å; I222-T225 PolarHBondContact O-N 2.92Å; I222-L226 HydrophobicContact CG2-CD1 3.89Å; I222-L226 HydrophobicContact CG2-CG 4.08Å; I222-L226 VanDerWaalsContact O-CG 3.3Å; I222-L226 WeakPolarHBondContact O-CG 3.43Å; I222-L226 PolarHBondContact O-N 3.47Å
223L98.8Very high97Very high0 Ų08.3 Ų8.30%05%0.051CC..Hα-helixtrans-55.8-45.3178.9172.959.8000111.8T130 M134 C219 G220 L227 V264 L267 I268 L271 F290T130-L223 HydrophobicContact CG2-CD1 3.48Å; T130-L223 VanDerWaalsContact CG2-CD1 3.48Å; M134-L223 HydrophobicContact CE-CB 3.97Å; M134-L223 HydrophobicContact CG-CB 4.35Å; M134-L223 HydrophobicContact CG-CD1 3.87Å; M134-L223 HydrophobicContact SD-CB 4.04Å; C219-L223 VanDerWaalsContact O-CB 3.32Å; C219-L223 WeakPolarHBondContact O-CB 3.44Å; C219-L223 PolarHBondContact O-N 3.48Å; G220-L223 PolarHBondContact O-N 2.86Å; L223-L227 HydrophobicContact CD1-CD1 3.89Å; L223-L227 HydrophobicContact CG-CD1 4.47Å; L223-L227 WeakPolarHBondContact O-CG 3.49Å; L223-L227 PolarHBondContact O-N 3.23Å; L223-V264 HydrophobicContact CD1-CG2 3.93Å; L223-V264 HydrophobicContact CD2-CG2 4.44Å; L223-V264 HydrophobicContact CG-CG2 4.48Å; L223-L267 HydrophobicContact CD2-CB 4.28Å; L223-L267 HydrophobicContact CD2-CD2 3.7Å; L223-L267 HydrophobicContact CD2-CG 3.73Å; L223-I268 HydrophobicContact CB-CG1 4.35Å; L223-I268 HydrophobicContact CD2-CD1 4.4Å; L223-I268 HydrophobicContact CD2-CG1 3.45Å; L223-I268 VanDerWaalsContact CD2-CG1 3.45Å; L223-I268 HydrophobicContact CG-CD1 4.08Å; L223-I268 HydrophobicContact CG-CG1 3.55Å; L223-L271 HydrophobicContact CD2-CD1 4.08Å; L223-F290 HydrophobicContact CD1-CE1 4.47Å
224F98.6Very high96.7Very high7 Ų79.5 Ų9.53%0.0315%0.053CC..Hα-helixtrans-59.1-49.1174.8-174.7-74.6000110.9G220 V221 I222 L226 L227 A228 S230 P232 Y250 F252 W257 I268G220-F224 WeakPolarHBondContact O-CB 3.23Å; G220-F224 PolarHBondContact O-N 2.94Å; V221-F224 PolarHBondContact O-N 3.38Å; I222-F224 VanDerWaalsContact C-N 3.31Å; I222-F224 PolarHBondContact O-N 3.14Å; F224-L226 PolarHBondContact O-N 2.9Å; F224-L227 PolarHBondContact O-N 3Å; F224-L227 VanDerWaalsContact O-N 3.17Å; F224-A228 HydrophobicContact CD1-CB 3.97Å; F224-A228 HydrophobicContact CE1-CB 3.67Å; F224-A228 HydrophobicContact CZ-CB 4.42Å; F224-A228 WeakPolarHBondContact O-CB 3.3Å; F224-A228 PolarHBondContact O-N 3.45Å; F224-S230 WeakPolarHBondContact CD1-O 3.32Å; F224-S230 WeakPolarHBondContact CE1-O 3.44Å; F224-P232 HydrophobicContact CB-CB 4.38Å; F224-P232 HydrophobicContact CB-CG 4.17Å; F224-P232 HydrophobicContact CD1-CB 3.74Å; F224-P232 HydrophobicContact CD1-CG 4.06Å; F224-P232 HydrophobicContact CD2-CB 3.85Å; F224-P232 HydrophobicContact CE1-CB 3.91Å; F224-P232 HydrophobicContact CE2-CB 4.02Å; F224-P232 HydrophobicContact CG-CB 3.73Å; F224-P232 HydrophobicContact CG-CG 4.02Å; F224-P232 HydrophobicContact CZ-CB 4.04Å; F224-Y250 HydrophobicContact CD2-CD2 4.35Å; F224-Y250 HydrophobicContact CE2-CD2 4.04Å; F224-F252 HydrophobicContact CD2-CD1 4.43Å; F224-F252 HydrophobicContact CD2-CE1 4.07Å; F224-F252 AromaticContact CE2-CD1 3.95Å; F224-F252 HydrophobicContact CE2-CD1 3.95Å; F224-F252 HydrophobicContact CE2-CE1 4.02Å; F224-W257 AromaticContact CD1-CZ2 3.96Å; F224-W257 HydrophobicContact CD1-CZ2 3.96Å; F224-W257 AromaticContact CD2-CH2 3.98Å; F224-W257 HydrophobicContact CD2-CH2 3.98Å; F224-W257 AromaticContact CD2-CZ2 3.43Å; F224-W257 HydrophobicContact CD2-CZ2 3.43Å; F224-W257 VanDerWaalsContact CD2-CZ2 3.43Å; F224-W257 AromaticContact CE1-CZ2 3.94Å; F224-W257 HydrophobicContact CE1-CZ2 3.94Å; F224-W257 AromaticContact CE2-CE2 3.78Å; F224-W257 HydrophobicContact CE2-CH2 4.31Å; F224-W257 AromaticContact CE2-CZ2 3.42Å; F224-W257 HydrophobicContact CE2-CZ2 3.42Å; F224-W257 VanDerWaalsContact CE2-CZ2 3.42Å; F224-W257 AromaticContact CE2-NE1 3.87Å; F224-W257 HydrophobicContact CG-CH2 4.27Å; F224-W257 AromaticContact CG-CZ2 3.71Å; F224-W257 HydrophobicContact CG-CZ2 3.71Å; F224-W257 AromaticContact CZ-CE2 3.83Å; F224-W257 AromaticContact CZ-CZ2 3.68Å; F224-W257 HydrophobicContact CZ-CZ2 3.68Å; F224-W257 AromaticContact CZ-NE1 3.51Å; F224-I268 HydrophobicContact CB-CD1 4.38Å; F224-I268 HydrophobicContact CB-CG2 4.45Å; F224-I268 HydrophobicContact CD2-CD1 4.47Å; F224-I268 HydrophobicContact CD2-CG2 4.13Å
225T97.3Very high96.3Very high6 Ų612.7 Ų12.74%0.0377%0.067CC..Hα-helixtrans-67.2-38.8-173.8-59.10000112.2L119 V221 I222 L227 G229 P231L119-T225 HydrophobicContact CD2-CG2 3.78Å; V221-T225 VanDerWaalsContact O-CB 3.29Å; V221-T225 WeakPolarHBondContact O-CB 3.32Å; V221-T225 PolarHBondContact O-N 2.82Å; V221-T225 PolarHBondContact O-OG1 3.48Å; I222-T225 PolarHBondContact O-N 2.92Å; T225-L227 PolarHBondContact O-N 3.46Å; T225-G229 VanDerWaalsContact O-CA 3.28Å; T225-G229 WeakPolarHBondContact O-CA 3.44Å; T225-G229 PolarHBondContact O-N 3.22Å; T225-P231 WeakPolarHBondContact OG1-CA 3.44Å
226L97.8Very high95.7Very high0 Ų020.9 Ų20.90%010%0.098CC..Hα-helixtrans-61-32.8175.1-67.3178.4000112.2L115 L119 L125 T130 I133 M134 I222 F224L115-L226 HydrophobicContact CD1-CD2 4.08Å; L115-L226 HydrophobicContact CD2-CD1 4.44Å; L115-L226 HydrophobicContact CD2-CD2 3.97Å; L115-L226 HydrophobicContact CG-CD2 4.06Å; L119-L226 HydrophobicContact CD1-CD2 4.37Å; L119-L226 HydrophobicContact CD2-CD2 4.29Å; L125-L226 HydrophobicContact CD1-CB 4.41Å; L125-L226 HydrophobicContact CD1-CD2 3.88Å; L125-L226 PolarHBondContact N-O 3.15Å; T130-L226 HydrophobicContact CG2-CB 4.06Å; T130-L226 HydrophobicContact CG2-CD1 4.13Å; I133-L226 HydrophobicContact CG2-CD1 3.91Å; M134-L226 HydrophobicContact CG-CD1 4.3Å; M134-L226 HydrophobicContact SD-CD1 4.04Å; I222-L226 HydrophobicContact CG2-CD1 3.89Å; I222-L226 HydrophobicContact CG2-CG 4.08Å; I222-L226 VanDerWaalsContact O-CG 3.3Å; I222-L226 WeakPolarHBondContact O-CG 3.43Å; I222-L226 PolarHBondContact O-N 3.47Å; F224-L226 PolarHBondContact O-N 2.9Å
227L96.6Very high95.2Very high2 Ų227.8 Ų27.81%0.0112%0.124CC..Hα-helixtrans-90.9-39.8-177-67.1167.5000113.5E127 T130 L223 F224 T225 W257 R260 V264 I268E127-L227 HydrophobicContact CG-CD2 3.85Å; T130-L227 HydrophobicContact CG2-CD1 4.39Å; T130-L227 HydrophobicContact CG2-CD2 4.07Å; T130-L227 HydrophobicContact CG2-CG 4.02Å; T130-L227 WeakPolarHBondContact OG1-CD2 3.43Å; L223-L227 HydrophobicContact CD1-CD1 3.89Å; L223-L227 HydrophobicContact CG-CD1 4.47Å; L223-L227 WeakPolarHBondContact O-CG 3.49Å; L223-L227 PolarHBondContact O-N 3.23Å; F224-L227 PolarHBondContact O-N 3Å; F224-L227 VanDerWaalsContact O-N 3.17Å; T225-L227 PolarHBondContact O-N 3.46Å; L227-W257 HydrophobicContact CB-CH2 3.86Å; L227-W257 HydrophobicContact CB-CZ2 4.47Å; L227-W257 HydrophobicContact CB-CZ3 4.29Å; L227-W257 HydrophobicContact CD1-CH2 4.12Å; L227-W257 HydrophobicContact CD1-CZ3 4.18Å; L227-R260 PolarHBondContact O-NH2 3.49Å; L227-V264 HydrophobicContact CD1-CB 4.37Å; L227-V264 HydrophobicContact CD1-CG1 4.04Å; L227-V264 HydrophobicContact CD1-CG2 3.41Å; L227-V264 VanDerWaalsContact CD1-CG2 3.41Å; L227-I268 HydrophobicContact CD1-CD1 4.21Å
228A93.3Very high94.6Very high11 Ų1132.4 Ų32.49%0.09115%0.146CC..Hα-helixtrans-81.3-32179.400000112.2F224 W257F224-A228 HydrophobicContact CD1-CB 3.97Å; F224-A228 HydrophobicContact CE1-CB 3.67Å; F224-A228 HydrophobicContact CZ-CB 4.42Å; F224-A228 WeakPolarHBondContact O-CB 3.3Å; F224-A228 PolarHBondContact O-N 3.45Å; A228-W257 HydrophobicContact CB-CZ2 3.82Å
229G90.3Very high94.1Very high5 Ų534 Ų345%0.05215%0.153CC..SBendtrans78.56.5-166.700000113.4V123 T225 R370V123-G229 WeakPolarHBondContact O-CA 3.42Å; T225-G229 VanDerWaalsContact O-CA 3.28Å; T225-G229 WeakPolarHBondContact O-CA 3.44Å; T225-G229 PolarHBondContact O-N 3.22Å; G229-R370 WeakPolarHBondContact O-CD 3.3Å; G229-R370 PolarHBondContact O-NE 3.48Å
230S90.8Very high93.8Very high46 Ų4636.9 Ų36.932%0.32217%0.168SC..SBendtrans-145.5151176.857.80000110.3F224F224-S230 WeakPolarHBondContact CD1-O 3.32Å; F224-S230 WeakPolarHBondContact CE1-O 3.44Å
231P94.4Very high93.6Very high12 Ų1237.5 Ų37.58%0.07817%0.171CC..  trans-66.4151.4178.229.2-38.4000112.6T225 F233 W234T225-P231 WeakPolarHBondContact OG1-CA 3.44Å; P231-F233 VanDerWaalsContact C-N 3.34Å; P231-W234 HydrophobicContact CG-CB 3.96Å; P231-W234 HydrophobicContact CG-CG 4.45Å
232P96.4Very high93.3Very high12 Ų1238.5 Ų38.58%0.07818%0.176CC..SBendtrans-67.4-34.1175.924.5-30.1000112.8V221 F224 Y250 L272V221-P232 HydrophobicContact CB-CG 4.36Å; V221-P232 HydrophobicContact CG1-CG 4.02Å; V221-P232 HydrophobicContact CG2-CG 4.22Å; F224-P232 HydrophobicContact CB-CB 4.38Å; F224-P232 HydrophobicContact CB-CG 4.17Å; F224-P232 HydrophobicContact CD1-CB 3.74Å; F224-P232 HydrophobicContact CD1-CG 4.06Å; F224-P232 HydrophobicContact CD2-CB 3.85Å; F224-P232 HydrophobicContact CE1-CB 3.91Å; F224-P232 HydrophobicContact CE2-CB 4.02Å; F224-P232 HydrophobicContact CG-CB 3.73Å; F224-P232 HydrophobicContact CG-CG 4.02Å; F224-P232 HydrophobicContact CZ-CB 4.04Å; P232-Y250 HydrophobicContact CB-CG 4.35Å; P232-L272 HydrophobicContact CB-CD1 4.31Å; P232-L272 HydrophobicContact CG-CD1 4.26Å
233F95.9Very high93.1Very high0 Ų043.9 Ų43.90%020%0.197CC..SBendtrans-115114.9179.6-45.1-72.4000108.8W217 V221 P231 M241 M244 I245 Y250 L272W217-F233 AromaticContact CE2-CE2 3.97Å; W217-F233 HydrophobicContact CH2-CE2 4.1Å; W217-F233 AromaticContact CH2-CZ 3.73Å; W217-F233 HydrophobicContact CH2-CZ 3.73Å; W217-F233 HydrophobicContact CZ2-CD2 4.29Å; W217-F233 HydrophobicContact CZ2-CE1 4.45Å; W217-F233 AromaticContact CZ2-CE2 3.34Å; W217-F233 HydrophobicContact CZ2-CE2 3.34Å; W217-F233 AromaticContact CZ2-CZ 3.44Å; W217-F233 HydrophobicContact CZ2-CZ 3.44Å; W217-F233 VanDerWaalsContact CZ2-CZ 3.44Å; V221-F233 HydrophobicContact CG2-CD2 4.41Å; V221-F233 HydrophobicContact CG2-CE2 4.14Å; P231-F233 VanDerWaalsContact C-N 3.34Å; F233-M241 HydrophobicContact CB-CG 4.3Å; F233-M244 HydrophobicContact CD1-CB 4.15Å; F233-I245 HydrophobicContact CB-CD1 4.34Å; F233-I245 HydrophobicContact CB-CG1 3.68Å; F233-I245 HydrophobicContact CD1-CG1 4.2Å; F233-I245 HydrophobicContact CD2-CG1 3.74Å; F233-I245 HydrophobicContact CE2-CG1 4.46Å; F233-I245 HydrophobicContact CG-CG1 3.59Å; F233-Y250 AromaticContact CE1-CD1 3.99Å; F233-Y250 HydrophobicContact CE1-CD1 3.99Å; F233-Y250 HydrophobicContact CE1-CG 4.36Å; F233-Y250 AromaticContact CZ-CD1 3.91Å; F233-Y250 HydrophobicContact CZ-CD1 3.91Å; F233-Y250 HydrophobicContact CZ-CG 4.43Å; F233-L272 HydrophobicContact CE2-CD1 4.47Å; F233-L272 HydrophobicContact CE2-CD2 4.32Å; F233-L272 HydrophobicContact CZ-CD1 4.41Å
234W90.9Very high92.9Very high85 Ų8546.3 Ų46.332%0.32221%0.209SC..  trans-154.4135.1174.3-175.281.3000111.7P231 A371 Q375P231-W234 HydrophobicContact CG-CB 3.96Å; P231-W234 HydrophobicContact CG-CG 4.45Å; W234-A371 HydrophobicContact CB-CB 4.45Å; W234-A371 HydrophobicContact CD2-CB 3.4Å; W234-A371 HydrophobicContact CE3-CB 4.05Å; W234-A371 HydrophobicContact CG-CB 3.56Å; W234-A371 HydrophobicContact CH2-CB 4.46Å; W234-A371 HydrophobicContact CZ2-CB 3.9Å; W234-Q375 HydrophobicContact CH2-CG 4.26Å
235H90.8Very high92.8Very high72 Ų7246 Ų4633%0.33321%0.207SC..  trans-150.9150.8170.8-168.7-88.6000109.6R237 L240 M241 M244H235-R237 VanDerWaalsContact C-N 3.27Å; H235-R237 PolarHBondContact ND1-N 3.36Å; H235-R237 PolarHBondContact ND1-O 2.94Å; H235-R237 PolarHBondContact O-N 2.82Å; H235-L240 HydrophobicContact CB-CB 4.08Å; H235-L240 WeakPolarHBondContact CE1-CD1 3.41Å; H235-L240 WeakPolarHBondContact ND1-CB 2.95Å; H235-M241 HydrophobicContact CB-CB 4.13Å; H235-M244 HydrophobicContact CB-SD 4.47Å
236R85.6Confident92.7Very high173 Ų17347.5 Ų47.565%0.65321%0.214SC*.SBendtrans-62.2-35.9179.7-176.1178.1177.7-174.5-0.3112.8
237R88.1Confident92.6Very high148 Ų14851.4 Ų51.456%0.55823%0.233SC*.SBendtrans-90.4116.9170.9-62.4179.163.8-170.8-0.8108.6H235 I239 L240 M241H235-R237 VanDerWaalsContact C-N 3.27Å; H235-R237 PolarHBondContact ND1-N 3.36Å; H235-R237 PolarHBondContact ND1-O 2.94Å; H235-R237 PolarHBondContact O-N 2.82Å; R237-I239 VanDerWaalsContact C-N 3.26Å; R237-I239 HydrophobicContact CB-CG2 4.25Å; R237-I239 PolarHBondContact O-N 3.08Å; R237-L240 HydrophobicContact CB-CD1 4.24Å; R237-L240 HydrophobicContact CB-CG 4.34Å; R237-L240 PolarHBondContact O-N 3.34Å; R237-L240 VanDerWaalsContact O-N 3.07Å; R237-M241 PolarHBondContact O-N 3.46Å
238Q87.8Confident92.5Very high97 Ų9752.1 Ų52.145%0.45324%0.241SC..Hα-helixtrans-53.2-43-179.1-178.9167-41.100112L240 M241 L242Q238-L240 PolarHBondContact O-N 3.25Å; Q238-L240 VanDerWaalsContact O-N 3.15Å; Q238-M241 HydrophobicContact CG-CE 4.2Å; Q238-M241 WeakPolarHBondContact O-CA 3.47Å; Q238-M241 VanDerWaalsContact O-CB 3.32Å; Q238-M241 WeakPolarHBondContact O-CB 3.3Å; Q238-M241 PolarHBondContact O-N 3.04Å; Q238-L242 HydrophobicContact CG-CD1 4.28Å; Q238-L242 HydrophobicContact CG-CG 4.24Å; Q238-L242 WeakPolarHBondContact O-CG 3.46Å; Q238-L242 PolarHBondContact O-N 2.85Å
239I87.9Confident92.6Very high38 Ų3856.8 Ų56.820%0.19526%0.26CS..Hα-helixtrans-53.5-37.7178.2-158.471000114R237 R243 V404R237-I239 VanDerWaalsContact C-N 3.26Å; R237-I239 HydrophobicContact CB-CG2 4.25Å; R237-I239 PolarHBondContact O-N 3.08Å; I239-R243 PolarHBondContact O-N 3.38Å; I239-V404 HydrophobicContact CD1-CB 4.5Å; I239-V404 HydrophobicContact CD1-CG2 3.3Å; I239-V404 HydrophobicContact CG1-CG2 4.05Å
240L92.8Very high92.9Very high60 Ų6059 Ų5931%0.31427%0.267SS..Hα-helixtrans-77.4-31.9178.7-66.8176.2000111.5H235 R237 Q238 R243 M244H235-L240 HydrophobicContact CB-CB 4.08Å; H235-L240 WeakPolarHBondContact CE1-CD1 3.41Å; H235-L240 WeakPolarHBondContact ND1-CB 2.95Å; R237-L240 HydrophobicContact CB-CD1 4.24Å; R237-L240 HydrophobicContact CB-CG 4.34Å; R237-L240 PolarHBondContact O-N 3.34Å; R237-L240 VanDerWaalsContact O-N 3.07Å; Q238-L240 PolarHBondContact O-N 3.25Å; Q238-L240 VanDerWaalsContact O-N 3.15Å; L240-R243 PolarHBondContact O-N 3.23Å; L240-M244 VanDerWaalsContact O-CG 3.3Å; L240-M244 WeakPolarHBondContact O-CG 3.34Å; L240-M244 PolarHBondContact O-N 3.3Å
241M93.8Very high93.1Very high13 Ų1363.5 Ų63.56%0.06428%0.283CS..Hα-helixtrans-65.4-43.6171.4-180-174.274.600110.9P191 F233 H235 R237 Q238 R243 M244 I245P191-M241 HydrophobicContact CB-CE 3.75Å; F233-M241 HydrophobicContact CB-CG 4.3Å; H235-M241 HydrophobicContact CB-CB 4.13Å; R237-M241 PolarHBondContact O-N 3.46Å; Q238-M241 HydrophobicContact CG-CE 4.2Å; Q238-M241 WeakPolarHBondContact O-CA 3.47Å; Q238-M241 VanDerWaalsContact O-CB 3.32Å; Q238-M241 WeakPolarHBondContact O-CB 3.3Å; Q238-M241 PolarHBondContact O-N 3.04Å; M241-R243 VanDerWaalsContact C-N 3.32Å; M241-R243 PolarHBondContact O-N 3.44Å; M241-M244 WeakPolarHBondContact O-CB 3.18Å; M241-M244 PolarHBondContact O-N 2.84Å; M241-I245 HydrophobicContact CG-CD1 4.32Å; M241-I245 WeakPolarHBondContact O-CG1 3.06Å; M241-I245 PolarHBondContact O-N 2.84Å
242L92.4Very high93.1Very high21 Ų2165.7 Ų65.711%0.1129%0.292CS..Hα-helixtrans-60.9-41.6175.7-62.9-178.2000111.4P191 L199 Q238 M244 I245 M246P191-L242 HydrophobicContact CB-CD2 4.49Å; L199-L242 HydrophobicContact CD1-CB 4.19Å; L199-L242 HydrophobicContact CD1-CD2 3.99Å; L199-L242 HydrophobicContact CD2-CD2 3.95Å; Q238-L242 HydrophobicContact CG-CD1 4.28Å; Q238-L242 HydrophobicContact CG-CG 4.24Å; Q238-L242 WeakPolarHBondContact O-CG 3.46Å; Q238-L242 PolarHBondContact O-N 2.85Å; L242-M244 PolarHBondContact O-N 2.91Å; L242-I245 HydrophobicContact CD2-CD1 4.39Å; L242-I245 WeakPolarHBondContact O-CB 3.2Å; L242-I245 PolarHBondContact O-N 3.16Å; L242-M246 WeakPolarHBondContact O-CG 3.48Å; L242-M246 PolarHBondContact O-N 3.26Å
243R93.9Very high92.7Very high113 Ų11367 Ų6743%0.42630%0.301SS..Hα-helixtrans-60-44.6172.8-176175.6176.1166.42.7112.6I239 L240 M241 I245 M246 E247I239-R243 PolarHBondContact O-N 3.38Å; L240-R243 PolarHBondContact O-N 3.23Å; M241-R243 VanDerWaalsContact C-N 3.32Å; M241-R243 PolarHBondContact O-N 3.44Å; R243-I245 VanDerWaalsContact C-N 3.28Å; R243-I245 PolarHBondContact O-N 3.21Å; R243-M246 PolarHBondContact O-N 3.36Å; R243-E247 HydrophobicContact CG-CG 4.42Å; R243-E247 WeakPolarHBondContact CG-OE1 3.47Å; R243-E247 IonicContact CZ-OE1 3.33Å; R243-E247 IonicContact NE-OE1 2.68Å; R243-E247 PolarHBondContact NE-OE1 3.5Å; R243-E247 IonicContact NH2-OE1 2.89Å; R243-E247 PolarHBondContact NH2-OE1 3.31Å; R243-E247 WeakPolarHBondContact O-CB 3.4Å; R243-E247 WeakPolarHBondContact O-CG 3.48Å; R243-E247 PolarHBondContact O-N 3.37Å
244M96Very high91.8Very high51 Ų5170.8 Ų70.825%0.25133%0.328SS..Hα-helixtrans-59.9-39.1175.5-68.8171.970.500112.2F233 H235 L240 M241 L242 G248 Q249F233-M244 HydrophobicContact CD1-CB 4.15Å; H235-M244 HydrophobicContact CB-SD 4.47Å; L240-M244 VanDerWaalsContact O-CG 3.3Å; L240-M244 WeakPolarHBondContact O-CG 3.34Å; L240-M244 PolarHBondContact O-N 3.3Å; M241-M244 WeakPolarHBondContact O-CB 3.18Å; M241-M244 PolarHBondContact O-N 2.84Å; L242-M244 PolarHBondContact O-N 2.91Å; M244-G248 PolarHBondContact O-N 2.79Å; M244-Q249 PolarHBondContact O-N 3.41Å
245I96.6Very high91.5Very high0 Ų069.7 Ų69.70%033%0.332CS..Hα-helixtrans-62.8-53.2175.1-69.4166.5000109.8P191 L194 P196 L199 W217 F233 M241 L242 R243 E247 G248P191-I245 VanDerWaalsContact O-CD1 3.25Å; P191-I245 WeakPolarHBondContact O-CD1 3.46Å; L194-I245 VanDerWaalsContact O-CG2 3.22Å; L194-I245 WeakPolarHBondContact O-CG2 3.48Å; P196-I245 HydrophobicContact CG-CG2 4.29Å; P196-I245 WeakPolarHBondContact CG-O 3.29Å; L199-I245 HydrophobicContact CD1-CB 4.06Å; L199-I245 HydrophobicContact CD1-CG2 3.69Å; W217-I245 HydrophobicContact CZ2-CG2 3.91Å; F233-I245 HydrophobicContact CB-CD1 4.34Å; F233-I245 HydrophobicContact CB-CG1 3.68Å; F233-I245 HydrophobicContact CD1-CG1 4.2Å; F233-I245 HydrophobicContact CD2-CG1 3.74Å; F233-I245 HydrophobicContact CE2-CG1 4.46Å; F233-I245 HydrophobicContact CG-CG1 3.59Å; M241-I245 HydrophobicContact CG-CD1 4.32Å; M241-I245 WeakPolarHBondContact O-CG1 3.06Å; M241-I245 PolarHBondContact O-N 2.84Å; L242-I245 HydrophobicContact CD2-CD1 4.39Å; L242-I245 WeakPolarHBondContact O-CB 3.2Å; L242-I245 PolarHBondContact O-N 3.16Å; R243-I245 VanDerWaalsContact C-N 3.28Å; R243-I245 PolarHBondContact O-N 3.21Å; I245-E247 VanDerWaalsContact C-N 3.26Å; I245-E247 PolarHBondContact O-N 3.19Å; I245-G248 PolarHBondContact O-N 3.49Å
246M94.1Very high91.2Very high39 Ų3969 Ų6919%0.19233%0.329CS..Hα-helixtrans-57.9-37.5-178.7-70.5174.172.300113.2L199 K200 M203 L242 R243 G248 V404L199-M246 HydrophobicContact CB-CG 3.95Å; L199-M246 HydrophobicContact CB-SD 4.27Å; L199-M246 HydrophobicContact CD1-CG 3.77Å; K200-M246 HydrophobicContact CG-CE 4.17Å; M203-M246 HydrophobicContact CE-SD 4Å; M203-M246 HydrophobicContact SD-CE 3.85Å; M203-M246 HydrophobicContact SD-SD 3.95Å; L242-M246 WeakPolarHBondContact O-CG 3.48Å; L242-M246 PolarHBondContact O-N 3.26Å; R243-M246 PolarHBondContact O-N 3.36Å; M246-G248 VanDerWaalsContact C-N 3.34Å; M246-V404 HydrophobicContact SD-CG1 4.06Å
247E95.3Very high91.5Very high82 Ų8261 Ų6138%0.38330%0.299SS..THydrogen-bonded Turntrans-85-5.7178.3-64.6176-176.400112.9R243 I245 Q249R243-E247 HydrophobicContact CG-CG 4.42Å; R243-E247 WeakPolarHBondContact CG-OE1 3.47Å; R243-E247 IonicContact CZ-OE1 3.33Å; R243-E247 IonicContact NE-OE1 2.68Å; R243-E247 PolarHBondContact NE-OE1 3.5Å; R243-E247 IonicContact NH2-OE1 2.89Å; R243-E247 PolarHBondContact NH2-OE1 3.31Å; R243-E247 WeakPolarHBondContact O-CB 3.4Å; R243-E247 WeakPolarHBondContact O-CG 3.48Å; R243-E247 PolarHBondContact O-N 3.37Å; I245-E247 VanDerWaalsContact C-N 3.26Å; I245-E247 PolarHBondContact O-N 3.19Å; E247-Q249 HydrophobicContact CB-CG 3.86Å; E247-Q249 PolarHBondContact O-N 2.9Å; E247-Q249 PolarHBondContact OE2-NE2 3.37Å; E247-Q249 PolarHBondContact OE2-OE1 3.38Å
248G96.1Very high91.3Very high17 Ų1757.4 Ų57.418%0.17529%0.29CS..THydrogen-bonded Turntrans62.627.3-176.600000113.7M244 I245 M246 Y250M244-G248 PolarHBondContact O-N 2.79Å; I245-G248 PolarHBondContact O-N 3.49Å; M246-G248 VanDerWaalsContact C-N 3.34Å; G248-Y250 WeakPolarHBondContact O-CD1 3.3Å; G248-Y250 PolarHBondContact O-N 3.18Å
249Q94.8Very high91.2Very high108 Ų10856.4 Ų56.451%0.50529%0.288SS..  trans-85.595.7-174.2-73.8-176.29.400111.9M244 E247M244-Q249 PolarHBondContact O-N 3.41Å; E247-Q249 HydrophobicContact CB-CG 3.86Å; E247-Q249 PolarHBondContact O-N 2.9Å; E247-Q249 PolarHBondContact OE2-NE2 3.37Å; E247-Q249 PolarHBondContact OE2-OE1 3.38Å
250Y96.7Very high91.4Very high51 Ų5155.9 Ų55.920%0.228%0.284CS..  trans-131.5163.2168.267.7-83.2000110.3F224 P232 F233 G248 F252 I268 S269 L272F224-Y250 HydrophobicContact CD2-CD2 4.35Å; F224-Y250 HydrophobicContact CE2-CD2 4.04Å; P232-Y250 HydrophobicContact CB-CG 4.35Å; F233-Y250 AromaticContact CE1-CD1 3.99Å; F233-Y250 HydrophobicContact CE1-CD1 3.99Å; F233-Y250 HydrophobicContact CE1-CG 4.36Å; F233-Y250 AromaticContact CZ-CD1 3.91Å; F233-Y250 HydrophobicContact CZ-CD1 3.91Å; F233-Y250 HydrophobicContact CZ-CG 4.43Å; G248-Y250 WeakPolarHBondContact O-CD1 3.3Å; G248-Y250 PolarHBondContact O-N 3.18Å; Y250-F252 HydrophobicContact CD2-CZ 4.49Å; Y250-F252 HydrophobicContact CE2-CE1 4.11Å; Y250-F252 AromaticContact CE2-CE2 3.97Å; Y250-F252 HydrophobicContact CE2-CE2 3.97Å; Y250-F252 AromaticContact CE2-CZ 3.67Å; Y250-F252 HydrophobicContact CE2-CZ 3.67Å; Y250-I268 HydrophobicContact CE2-CG2 4.2Å; Y250-S269 VanDerWaalsContact OH-CA 3.23Å; Y250-S269 WeakPolarHBondContact OH-CA 3.46Å; Y250-S269 WeakPolarHBondContact OH-CB 3.38Å; Y250-S269 PolarHBondContact OH-OG 3.35Å; Y250-L272 HydrophobicContact CD1-CB 4.4Å; Y250-L272 HydrophobicContact CD1-CD1 4.07Å; Y250-L272 HydrophobicContact CD2-CD1 4.34Å; Y250-L272 HydrophobicContact CE1-CB 3.74Å; Y250-L272 HydrophobicContact CE1-CD1 4.02Å; Y250-L272 HydrophobicContact CE2-CD1 4.29Å; Y250-L272 HydrophobicContact CG-CD1 4.25Å
251Q94.5Very high91.4Very high141 Ų14154.8 Ų54.866%0.65928%0.281SS*.  trans-140143-178.451.1171.914.400112.1S253Q251-S253 VanDerWaalsContact C-N 3.27Å; Q251-S253 WeakPolarHBondContact CG-OG 3.31Å; Q251-S253 PolarHBondContact NE2-OG 3.43Å; Q251-S253 PolarHBondContact O-N 3.13Å; Q251-S253 VanDerWaalsContact O-N 3.12Å
252F95.3Very high91.4Very high58 Ų5858.2 Ų58.225%0.25431%0.306SS..  trans-85.867.1172.4-61-60.3000110.6F224 Y250 W257 K265 I268F224-F252 HydrophobicContact CD2-CD1 4.43Å; F224-F252 HydrophobicContact CD2-CE1 4.07Å; F224-F252 AromaticContact CE2-CD1 3.95Å; F224-F252 HydrophobicContact CE2-CD1 3.95Å; F224-F252 HydrophobicContact CE2-CE1 4.02Å; Y250-F252 HydrophobicContact CD2-CZ 4.49Å; Y250-F252 HydrophobicContact CE2-CE1 4.11Å; Y250-F252 AromaticContact CE2-CE2 3.97Å; Y250-F252 HydrophobicContact CE2-CE2 3.97Å; Y250-F252 AromaticContact CE2-CZ 3.67Å; Y250-F252 HydrophobicContact CE2-CZ 3.67Å; F252-W257 HydrophobicContact CB-CB 3.91Å; F252-W257 HydrophobicContact CB-CD2 4.14Å; F252-W257 HydrophobicContact CB-CG 3.81Å; F252-W257 AromaticContact CD1-CD2 3.53Å; F252-W257 HydrophobicContact CD1-CD2 3.53Å; F252-W257 AromaticContact CD1-CE2 3.71Å; F252-W257 AromaticContact CD1-CE3 3.58Å; F252-W257 HydrophobicContact CD1-CE3 3.58Å; F252-W257 HydrophobicContact CD1-CG 4.11Å; F252-W257 HydrophobicContact CD1-CH2 4.08Å; F252-W257 AromaticContact CD1-CZ2 3.99Å; F252-W257 HydrophobicContact CD1-CZ2 3.99Å; F252-W257 AromaticContact CD1-CZ3 3.86Å; F252-W257 HydrophobicContact CD1-CZ3 3.86Å; F252-W257 HydrophobicContact CE1-CD2 4.4Å; F252-W257 HydrophobicContact CE1-CE3 4.13Å; F252-W257 HydrophobicContact CE1-CH2 4.03Å; F252-W257 HydrophobicContact CE1-CZ2 4.25Å; F252-W257 AromaticContact CE1-CZ3 3.94Å; F252-W257 HydrophobicContact CE1-CZ3 3.94Å; F252-W257 HydrophobicContact CG-CD2 4.28Å; F252-W257 HydrophobicContact CG-CE3 4.4Å; F252-W257 HydrophobicContact CG-CG 4.46Å; F252-K265 HydrophobicContact CB-CD 4.5Å; F252-K265 HydrophobicContact CD1-CG 4.17Å; F252-K265 HydrophobicContact CD2-CB 4.37Å; F252-K265 HydrophobicContact CD2-CD 4.25Å; F252-K265 HydrophobicContact CD2-CG 4.29Å; F252-K265 HydrophobicContact CE1-CB 4.34Å; F252-K265 HydrophobicContact CE1-CG 4.13Å; F252-K265 HydrophobicContact CE2-CB 3.92Å; F252-K265 HydrophobicContact CE2-CG 4.26Å; F252-K265 HydrophobicContact CG-CD 4.21Å; F252-K265 HydrophobicContact CG-CG 4.24Å; F252-K265 HydrophobicContact CZ-CB 3.89Å; F252-K265 HydrophobicContact CZ-CG 4.16Å; F252-I268 HydrophobicContact CE1-CB 4.23Å; F252-I268 HydrophobicContact CE1-CD1 3.98Å; F252-I268 HydrophobicContact CE1-CG2 3.9Å; F252-I268 HydrophobicContact CZ-CB 4.05Å; F252-I268 HydrophobicContact CZ-CG2 3.84Å
253S87.3Confident91.6Very high39 Ų3959.7 Ų59.727%0.27332%0.316SS..  trans-68.1145.8-172.5-58.10000114.2Q251 E256 W257Q251-S253 VanDerWaalsContact C-N 3.27Å; Q251-S253 WeakPolarHBondContact CG-OG 3.31Å; Q251-S253 PolarHBondContact NE2-OG 3.43Å; Q251-S253 PolarHBondContact O-N 3.13Å; Q251-S253 VanDerWaalsContact O-N 3.12Å; S253-E256 PolarHBondContact O-N 3.19Å; S253-W257 VanDerWaalsContact O-CD1 3.31Å; S253-W257 PolarHBondContact O-N 3.23Å
254S77.2Confident91.7Very high80 Ų8054.3 Ų54.356%0.55930%0.296SS*.THydrogen-bonded Turntrans-72.8148.3166-57.30000110.4D258S254-D258 WeakPolarHBondContact CB-OD1 3.34Å; S254-D258 PolarHBondContact OG-OD1 3.12Å
255P84.5Confident91.8Very high62 Ų6254.3 Ų54.340%0.40329%0.294SS..THydrogen-bonded Turncis-90-82.934.7-37.4000115.4W257 D258P255-W257 VanDerWaalsContact C-N 3.28Å; P255-W257 PolarHBondContact O-N 3.32Å; P255-D258 PolarHBondContact O-N 3.33Å
256E85.2Confident91.9Very high59 Ų5957.5 Ų57.528%0.27631%0.312SS..THydrogen-bonded Turntrans-63.5-34.5-168.3-68.766.3-141.900112.6S253 R347S253-E256 PolarHBondContact O-N 3.19Å; E256-R347 IonicContact OE1-NH1 3.89Å; E256-R347 PolarHBondContact OE1-NH1 3.43Å
257W90.9Very high92.2Very high5 Ų555.7 Ų55.72%0.01930%0.303CS..THydrogen-bonded Turntrans-98.2-0.5-175.3-68.996.1000114.9F224 L227 A228 F252 S253 P255 D259 R260 K265 I268F224-W257 AromaticContact CD1-CZ2 3.96Å; F224-W257 HydrophobicContact CD1-CZ2 3.96Å; F224-W257 AromaticContact CD2-CH2 3.98Å; F224-W257 HydrophobicContact CD2-CH2 3.98Å; F224-W257 AromaticContact CD2-CZ2 3.43Å; F224-W257 HydrophobicContact CD2-CZ2 3.43Å; F224-W257 VanDerWaalsContact CD2-CZ2 3.43Å; F224-W257 AromaticContact CE1-CZ2 3.94Å; F224-W257 HydrophobicContact CE1-CZ2 3.94Å; F224-W257 AromaticContact CE2-CE2 3.78Å; F224-W257 HydrophobicContact CE2-CH2 4.31Å; F224-W257 AromaticContact CE2-CZ2 3.42Å; F224-W257 HydrophobicContact CE2-CZ2 3.42Å; F224-W257 VanDerWaalsContact CE2-CZ2 3.42Å; F224-W257 AromaticContact CE2-NE1 3.87Å; F224-W257 HydrophobicContact CG-CH2 4.27Å; F224-W257 AromaticContact CG-CZ2 3.71Å; F224-W257 HydrophobicContact CG-CZ2 3.71Å; F224-W257 AromaticContact CZ-CE2 3.83Å; F224-W257 AromaticContact CZ-CZ2 3.68Å; F224-W257 HydrophobicContact CZ-CZ2 3.68Å; F224-W257 AromaticContact CZ-NE1 3.51Å; L227-W257 HydrophobicContact CB-CH2 3.86Å; L227-W257 HydrophobicContact CB-CZ2 4.47Å; L227-W257 HydrophobicContact CB-CZ3 4.29Å; L227-W257 HydrophobicContact CD1-CH2 4.12Å; L227-W257 HydrophobicContact CD1-CZ3 4.18Å; A228-W257 HydrophobicContact CB-CZ2 3.82Å; F252-W257 HydrophobicContact CB-CB 3.91Å; F252-W257 HydrophobicContact CB-CD2 4.14Å; F252-W257 HydrophobicContact CB-CG 3.81Å; F252-W257 AromaticContact CD1-CD2 3.53Å; F252-W257 HydrophobicContact CD1-CD2 3.53Å; F252-W257 AromaticContact CD1-CE2 3.71Å; F252-W257 AromaticContact CD1-CE3 3.58Å; F252-W257 HydrophobicContact CD1-CE3 3.58Å; F252-W257 HydrophobicContact CD1-CG 4.11Å; F252-W257 HydrophobicContact CD1-CH2 4.08Å; F252-W257 AromaticContact CD1-CZ2 3.99Å; F252-W257 HydrophobicContact CD1-CZ2 3.99Å; F252-W257 AromaticContact CD1-CZ3 3.86Å; F252-W257 HydrophobicContact CD1-CZ3 3.86Å; F252-W257 HydrophobicContact CE1-CD2 4.4Å; F252-W257 HydrophobicContact CE1-CE3 4.13Å; F252-W257 HydrophobicContact CE1-CH2 4.03Å; F252-W257 HydrophobicContact CE1-CZ2 4.25Å; F252-W257 AromaticContact CE1-CZ3 3.94Å; F252-W257 HydrophobicContact CE1-CZ3 3.94Å; F252-W257 HydrophobicContact CG-CD2 4.28Å; F252-W257 HydrophobicContact CG-CE3 4.4Å; F252-W257 HydrophobicContact CG-CG 4.46Å; S253-W257 VanDerWaalsContact O-CD1 3.31Å; S253-W257 PolarHBondContact O-N 3.23Å; P255-W257 VanDerWaalsContact C-N 3.28Å; P255-W257 PolarHBondContact O-N 3.32Å; W257-D259 VanDerWaalsContact C-N 3.26Å; W257-D259 PolarHBondContact O-N 2.75Å; W257-R260 HydrophobicContact CD2-CG 4.49Å; W257-R260 HydrophobicContact CE3-CB 3.84Å; W257-R260 HydrophobicContact CE3-CG 3.81Å; W257-R260 HydrophobicContact CZ3-CB 4.28Å; W257-R260 HydrophobicContact CZ3-CG 4.24Å; W257-R260 PolarHBondContact O-N 2.89Å; W257-K265 HydrophobicContact CE3-CG 4.07Å; W257-K265 HydrophobicContact CZ3-CG 4.27Å; W257-K265 WeakPolarHBondContact O-CE 3.41Å; W257-K265 PolarHBondContact O-NZ 3.05Å; W257-I268 HydrophobicContact CH2-CD1 3.28Å; W257-I268 HydrophobicContact CZ2-CD1 4.35Å; W257-I268 HydrophobicContact CZ3-CD1 3.63Å
258D85.1Confident92.3Very high72 Ų7251.8 Ų51.839%0.38528%0.284SS..THydrogen-bonded Turntrans-67.4-26.6-175.4-76.7-8.8000113.9S254 P255 R309S254-D258 WeakPolarHBondContact CB-OD1 3.34Å; S254-D258 PolarHBondContact OG-OD1 3.12Å; P255-D258 PolarHBondContact O-N 3.33Å; D258-R309 PolarHBondContact O-NH1 3.37Å
259D85.5Confident92.4Very high76 Ų7652.9 Ų52.941%0.40629%0.289SS..THydrogen-bonded Turntrans-107.6-0.2-176.6-58.9-32000112.7W257 R309 R344W257-D259 VanDerWaalsContact C-N 3.26Å; W257-D259 PolarHBondContact O-N 2.75Å; D259-R309 IonicContact OD1-CZ 3.47Å; D259-R309 IonicContact OD1-NH1 2.7Å; D259-R309 IonicContact OD1-NH2 2.67Å; D259-R309 PolarHBondContact OD1-NH2 2.74Å; D259-R344 IonicContact OD2-CZ 3.99Å; D259-R344 IonicContact OD2-NH1 2.79Å; D259-R344 PolarHBondContact OD2-NH1 3.02Å
260R90.8Very high92.6Very high27 Ų2751.6 Ų51.610%0.10228%0.282CS..SBendtrans-85.5138.6179.7-57.8-59.8-175.91723.2110.7L125 E127 L227 W257 V264L125-R260 VanDerWaalsContact O-CZ 3.3Å; L125-R260 PolarHBondContact O-NH1 3.27Å; L125-R260 PolarHBondContact O-NH2 3.15Å; E127-R260 VanDerWaalsContact OE1-CA 3.26Å; E127-R260 WeakPolarHBondContact OE1-CA 3.41Å; L227-R260 PolarHBondContact O-NH2 3.49Å; W257-R260 HydrophobicContact CD2-CG 4.49Å; W257-R260 HydrophobicContact CE3-CB 3.84Å; W257-R260 HydrophobicContact CE3-CG 3.81Å; W257-R260 HydrophobicContact CZ3-CB 4.28Å; W257-R260 HydrophobicContact CZ3-CG 4.24Å; W257-R260 PolarHBondContact O-N 2.89Å; R260-V264 HydrophobicContact CB-CG1 4.24Å
261S93.1Very high92.7Very high36 Ų3649.2 Ų49.225%0.25227%0.272SS..  trans-59.6149.7-178.266.40000111.7E127 T263 V264 K265E127-S261 PolarHBondContact OE1-N 3.1Å; E127-S261 PolarHBondContact OE1-OG 2.89Å; E127-S261 WeakPolarHBondContact OE2-CB 3.36Å; E127-S261 PolarHBondContact OE2-OG 3.46Å; S261-T263 PolarHBondContact O-N 3.45Å; S261-V264 WeakPolarHBondContact O-CG1 3.47Å; S261-V264 PolarHBondContact O-N 3.19Å; S261-V264 PolarHBondContact OG-N 3.22Å; S261-K265 WeakPolarHBondContact O-CG 3.31Å; S261-K265 PolarHBondContact O-N 3.39Å
262S94.1Very high92.9Very high85 Ų8542.7 Ų42.759%0.59424%0.242SC*.Hα-helixtrans-63.3-31170.6490000111.3V264 K265 D266S262-V264 PolarHBondContact O-N 2.93Å; S262-K265 PolarHBondContact O-N 3.39Å; S262-D266 WeakPolarHBondContact O-CB 3.31Å; S262-D266 PolarHBondContact O-N 3.19Å
263T96.4Very high93.1Very high52 Ų5243.5 Ų43.532%0.31925%0.247SC..Hα-helixtrans-60-43.1178.8-45.90000112.5S261 L267 H288 P289 F290S261-T263 PolarHBondContact O-N 3.45Å; T263-L267 PolarHBondContact O-N 3Å; T263-L267 VanDerWaalsContact O-N 3.17Å; T263-H288 PolarHBondContact O-CE1 3.28Å; T263-P289 HydrophobicContact CG2-CB 4.15Å; T263-F290 HydrophobicContact CG2-CB 4.14Å
264V97.3Very high93.6Very high0 Ų043.4 Ų43.40%025%0.245CC..Hα-helixtrans-75.5-31.8178.574.50000112.4E127 L223 L227 R260 S261 S262 D266 L267 I268 F290E127-V264 HydrophobicContact CG-CG1 4.42Å; L223-V264 HydrophobicContact CD1-CG2 3.93Å; L223-V264 HydrophobicContact CD2-CG2 4.44Å; L223-V264 HydrophobicContact CG-CG2 4.48Å; L227-V264 HydrophobicContact CD1-CB 4.37Å; L227-V264 HydrophobicContact CD1-CG1 4.04Å; L227-V264 HydrophobicContact CD1-CG2 3.41Å; L227-V264 VanDerWaalsContact CD1-CG2 3.41Å; R260-V264 HydrophobicContact CB-CG1 4.24Å; S261-V264 WeakPolarHBondContact O-CG1 3.47Å; S261-V264 PolarHBondContact O-N 3.19Å; S261-V264 PolarHBondContact OG-N 3.22Å; S262-V264 PolarHBondContact O-N 2.93Å; V264-D266 VanDerWaalsContact C-N 3.33Å; V264-L267 PolarHBondContact O-N 2.95Å; V264-I268 VanDerWaalsContact O-CG1 3.31Å; V264-I268 WeakPolarHBondContact O-CG1 3.22Å; V264-I268 PolarHBondContact O-N 3.26Å; V264-F290 HydrophobicContact CB-CD2 3.76Å; V264-F290 HydrophobicContact CB-CE2 3.66Å; V264-F290 HydrophobicContact CB-CZ 4.44Å; V264-F290 HydrophobicContact CG2-CD2 3.85Å; V264-F290 HydrophobicContact CG2-CE1 4.37Å; V264-F290 HydrophobicContact CG2-CE2 3.48Å; V264-F290 VanDerWaalsContact CG2-CE2 3.48Å; V264-F290 HydrophobicContact CG2-CG 4.45Å; V264-F290 HydrophobicContact CG2-CZ 3.76Å
265K98.2Very high94.6Very high51 Ų5143 Ų4322%0.22224%0.236CC..Hα-helixtrans-63.7-40.9172.7-66.5176.8-175-179.20111.2F252 W257 S261 S262 I268 S269F252-K265 HydrophobicContact CB-CD 4.5Å; F252-K265 HydrophobicContact CD1-CG 4.17Å; F252-K265 HydrophobicContact CD2-CB 4.37Å; F252-K265 HydrophobicContact CD2-CD 4.25Å; F252-K265 HydrophobicContact CD2-CG 4.29Å; F252-K265 HydrophobicContact CE1-CB 4.34Å; F252-K265 HydrophobicContact CE1-CG 4.13Å; F252-K265 HydrophobicContact CE2-CB 3.92Å; F252-K265 HydrophobicContact CE2-CG 4.26Å; F252-K265 HydrophobicContact CG-CD 4.21Å; F252-K265 HydrophobicContact CG-CG 4.24Å; F252-K265 HydrophobicContact CZ-CB 3.89Å; F252-K265 HydrophobicContact CZ-CG 4.16Å; W257-K265 HydrophobicContact CE3-CG 4.07Å; W257-K265 HydrophobicContact CZ3-CG 4.27Å; W257-K265 WeakPolarHBondContact O-CE 3.41Å; W257-K265 PolarHBondContact O-NZ 3.05Å; S261-K265 WeakPolarHBondContact O-CG 3.31Å; S261-K265 PolarHBondContact O-N 3.39Å; S262-K265 PolarHBondContact O-N 3.39Å; K265-I268 PolarHBondContact O-N 2.69Å; K265-S269 PolarHBondContact O-N 3.21Å; K265-S269 PolarHBondContact O-OG 2.89Å
266D98.5Very high95.2Very high68 Ų6841.8 Ų41.836%0.36423%0.228SC..Hα-helixtrans-60.9-46.6174.6-174.860.3000111.8S262 V264 I268 S269 K270 H288S262-D266 WeakPolarHBondContact O-CB 3.31Å; S262-D266 PolarHBondContact O-N 3.19Å; V264-D266 VanDerWaalsContact C-N 3.33Å; D266-I268 PolarHBondContact O-N 3.44Å; D266-S269 PolarHBondContact O-N 2.99Å; D266-K270 WeakPolarHBondContact O-CG 3.45Å; D266-K270 PolarHBondContact O-N 3.49Å; D266-K270 WeakPolarHBondContact OD1-CE 3.47Å; D266-K270 IonicContact OD1-NZ 3.82Å; D266-K270 WeakPolarHBondContact OD2-CE 3.45Å; D266-K270 IonicContact OD2-NZ 3.8Å; D266-K270 PolarHBondContact OD2-NZ 3.32Å; D266-H288 IonicContact OD2-CE1 3.82Å; D266-H288 IonicContact OD2-NE2 2.76Å; D266-H288 PolarHBondContact OD2-NE2 3.45Å
267L98.7Very high95.7Very high1 Ų147.3 Ų47.31%0.00525%0.254CS..Hα-helixtrans-59.6-45.7175.3-179.958000112L223 T263 V264 S269 K270 L271 L280 A285 H288 F290 F291L223-L267 HydrophobicContact CD2-CB 4.28Å; L223-L267 HydrophobicContact CD2-CD2 3.7Å; L223-L267 HydrophobicContact CD2-CG 3.73Å; T263-L267 PolarHBondContact O-N 3Å; T263-L267 VanDerWaalsContact O-N 3.17Å; V264-L267 PolarHBondContact O-N 2.95Å; L267-S269 VanDerWaalsContact C-N 3.31Å; L267-S269 PolarHBondContact O-N 2.89Å; L267-K270 PolarHBondContact O-N 3.15Å; L267-L271 HydrophobicContact CD1-CD1 4.06Å; L267-L271 HydrophobicContact CD1-CG 4.22Å; L267-L271 HydrophobicContact CG-CD1 4.06Å; L267-L271 WeakPolarHBondContact O-CG 3.45Å; L267-L271 PolarHBondContact O-N 3.07Å; L267-L280 HydrophobicContact CD1-CD1 4.09Å; L267-A285 HydrophobicContact CD1-CB 4.39Å; L267-H288 HydrophobicContact CD1-CB 3.98Å; L267-F290 HydrophobicContact CD2-CB 3.89Å; L267-F290 HydrophobicContact CD2-CD1 3.52Å; L267-F290 HydrophobicContact CD2-CE1 4.33Å; L267-F290 HydrophobicContact CD2-CG 3.94Å; L267-F291 HydrophobicContact CD2-CD2 4.48Å; L267-F291 HydrophobicContact CD2-CE2 3.61Å; L267-F291 HydrophobicContact CD2-CZ 3.93Å
268I98.8Very high96.1Very high0 Ų053.5 Ų53.50%028%0.283CS..Hα-helixtrans-58.6-46176.5-70.4167000110.5L223 F224 L227 Y250 F252 W257 V264 K265 D266 K270 L271 L272L223-I268 HydrophobicContact CB-CG1 4.35Å; L223-I268 HydrophobicContact CD2-CD1 4.4Å; L223-I268 HydrophobicContact CD2-CG1 3.45Å; L223-I268 VanDerWaalsContact CD2-CG1 3.45Å; L223-I268 HydrophobicContact CG-CD1 4.08Å; L223-I268 HydrophobicContact CG-CG1 3.55Å; F224-I268 HydrophobicContact CB-CD1 4.38Å; F224-I268 HydrophobicContact CB-CG2 4.45Å; F224-I268 HydrophobicContact CD2-CD1 4.47Å; F224-I268 HydrophobicContact CD2-CG2 4.13Å; L227-I268 HydrophobicContact CD1-CD1 4.21Å; Y250-I268 HydrophobicContact CE2-CG2 4.2Å; F252-I268 HydrophobicContact CE1-CB 4.23Å; F252-I268 HydrophobicContact CE1-CD1 3.98Å; F252-I268 HydrophobicContact CE1-CG2 3.9Å; F252-I268 HydrophobicContact CZ-CB 4.05Å; F252-I268 HydrophobicContact CZ-CG2 3.84Å; W257-I268 HydrophobicContact CH2-CD1 3.28Å; W257-I268 HydrophobicContact CZ2-CD1 4.35Å; W257-I268 HydrophobicContact CZ3-CD1 3.63Å; V264-I268 VanDerWaalsContact O-CG1 3.31Å; V264-I268 WeakPolarHBondContact O-CG1 3.22Å; V264-I268 PolarHBondContact O-N 3.26Å; K265-I268 PolarHBondContact O-N 2.69Å; D266-I268 PolarHBondContact O-N 3.44Å; I268-K270 VanDerWaalsContact C-N 3.28Å; I268-K270 PolarHBondContact O-N 3.34Å; I268-L271 PolarHBondContact O-N 3.18Å; I268-L272 HydrophobicContact CG2-CD1 3.69Å; I268-L272 HydrophobicContact CG2-CG 4.18Å; I268-L272 WeakPolarHBondContact O-CB 3.48Å; I268-L272 PolarHBondContact O-N 2.82Å
269S98.6Very high96.7Very high39 Ų3950.5 Ų50.527%0.27327%0.266SS..Hα-helixtrans-65.1-32.2-178-65.80000113.6Y250 K265 D266 L267Y250-S269 VanDerWaalsContact OH-CA 3.23Å; Y250-S269 WeakPolarHBondContact OH-CA 3.46Å; Y250-S269 WeakPolarHBondContact OH-CB 3.38Å; Y250-S269 PolarHBondContact OH-OG 3.35Å; K265-S269 PolarHBondContact O-N 3.21Å; K265-S269 PolarHBondContact O-OG 2.89Å; D266-S269 PolarHBondContact O-N 2.99Å; L267-S269 VanDerWaalsContact C-N 3.31Å; L267-S269 PolarHBondContact O-N 2.89Å
270K98.7Very high97.3Very high82 Ų8248.3 Ų48.336%0.35725%0.254SS..Hα-helixtrans-79.3-21.4175.7-67.2175.2176.6160.90114.1D266 L267 I268 L280D266-K270 WeakPolarHBondContact O-CG 3.45Å; D266-K270 PolarHBondContact O-N 3.49Å; D266-K270 WeakPolarHBondContact OD1-CE 3.47Å; D266-K270 IonicContact OD1-NZ 3.82Å; D266-K270 WeakPolarHBondContact OD2-CE 3.45Å; D266-K270 IonicContact OD2-NZ 3.8Å; D266-K270 PolarHBondContact OD2-NZ 3.32Å; L267-K270 PolarHBondContact O-N 3.15Å; I268-K270 VanDerWaalsContact C-N 3.28Å; I268-K270 PolarHBondContact O-N 3.34Å; K270-L280 HydrophobicContact CB-CD1 3.45Å; K270-L280 VanDerWaalsContact CB-CD1 3.45Å; K270-L280 HydrophobicContact CB-CG 3.73Å; K270-L280 HydrophobicContact CD-CD1 3.98Å; K270-L280 HydrophobicContact CD-CG 4.49Å; K270-L280 HydrophobicContact CG-CD1 4.36Å; K270-L280 PolarHBondContact O-N 3.19Å
271L98.8Very high97.7Very high0 Ų050.1 Ų50.10%027%0.269CS..Hα-helixtrans-85.8-38.2171.7-70.4172000112.1L216 L223 L267 I268 Q273 R279 L280 A285L216-L271 HydrophobicContact CB-CD2 4.21Å; L216-L271 HydrophobicContact CD1-CD2 4.06Å; L223-L271 HydrophobicContact CD2-CD1 4.08Å; L267-L271 HydrophobicContact CD1-CD1 4.06Å; L267-L271 HydrophobicContact CD1-CG 4.22Å; L267-L271 HydrophobicContact CG-CD1 4.06Å; L267-L271 WeakPolarHBondContact O-CG 3.45Å; L267-L271 PolarHBondContact O-N 3.07Å; I268-L271 PolarHBondContact O-N 3.18Å; L271-Q273 PolarHBondContact O-N 3.33Å; L271-R279 VanDerWaalsContact O-CD 3.24Å; L271-R279 WeakPolarHBondContact O-CD 3.4Å; L271-R279 WeakPolarHBondContact O-CG 3.42Å; L271-R279 PolarHBondContact O-NE 2.94Å; L271-L280 HydrophobicContact CD2-CB 4.34Å; L271-A285 HydrophobicContact CD2-CB 4.22Å
272L98.7Very high98Very high5 Ų548.5 Ų48.53%0.02626%0.258CS..SBendtrans-88.341.2175.7-61.9-176.6000111.8W217 V221 P232 F233 Y250 I268W217-L272 HydrophobicContact CD2-CD2 3.94Å; W217-L272 HydrophobicContact CE3-CD2 4.12Å; W217-L272 HydrophobicContact CG-CD2 4.41Å; W217-L272 HydrophobicContact CZ2-CD2 4.39Å; W217-L272 HydrophobicContact CZ3-CB 4.27Å; W217-L272 HydrophobicContact CZ3-CD2 4.43Å; V221-L272 HydrophobicContact CG2-CD2 3.78Å; P232-L272 HydrophobicContact CB-CD1 4.31Å; P232-L272 HydrophobicContact CG-CD1 4.26Å; F233-L272 HydrophobicContact CE2-CD1 4.47Å; F233-L272 HydrophobicContact CE2-CD2 4.32Å; F233-L272 HydrophobicContact CZ-CD1 4.41Å; Y250-L272 HydrophobicContact CD1-CB 4.4Å; Y250-L272 HydrophobicContact CD1-CD1 4.07Å; Y250-L272 HydrophobicContact CD2-CD1 4.34Å; Y250-L272 HydrophobicContact CE1-CB 3.74Å; Y250-L272 HydrophobicContact CE1-CD1 4.02Å; Y250-L272 HydrophobicContact CE2-CD1 4.29Å; Y250-L272 HydrophobicContact CG-CD1 4.25Å; I268-L272 HydrophobicContact CG2-CD1 3.69Å; I268-L272 HydrophobicContact CG2-CG 4.18Å; I268-L272 WeakPolarHBondContact O-CB 3.48Å; I268-L272 PolarHBondContact O-N 2.82Å
273Q98.5Very high98.1Very high75 Ų7549.9 Ų49.935%0.3526%0.255SS..  trans-85.6126.2173.8-176.36019.800109.1L271 D275 E278 R279L271-Q273 PolarHBondContact O-N 3.33Å; Q273-D275 WeakPolarHBondContact CG-O 3.25Å; Q273-E278 HydrophobicContact CG-CB 3.63Å; Q273-R279 HydrophobicContact CB-CB 4.14Å; Q273-R279 HydrophobicContact CB-CG 4.36Å; Q273-R279 PolarHBondContact O-NE 3.35Å; Q273-R279 PolarHBondContact O-NH2 3.22Å
274V98.1Very high98.2Very high37 Ų3752 Ų5222%0.22426%0.261CS..SBendtrans-67.2-38.5-175.2173.50000111.7P196 W217 P276P196-V274 HydrophobicContact CB-CG1 4.02Å; P196-V274 HydrophobicContact CG-CB 4.48Å; P196-V274 HydrophobicContact CG-CG1 4.18Å; P196-V274 HydrophobicContact CG-CG2 4.38Å; W217-V274 HydrophobicContact CZ3-CG2 4.45Å; V274-P276 WeakPolarHBondContact O-CD 3.39Å
275D97.7Very high98.3Very high71 Ų7152 Ų5238%0.3826%0.261SS..SBendtrans-76117172.6-171-17000109.4Q273 E277 E278 R279Q273-D275 WeakPolarHBondContact CG-O 3.25Å; D275-E277 PolarHBondContact O-N 2.97Å; D275-E277 PolarHBondContact OD1-N 3.4Å; D275-E278 HydrophobicContact CB-CB 4.2Å; D275-E278 HydrophobicContact CB-CG 4.21Å; D275-E278 PolarHBondContact O-N 3.03Å; D275-R279 PolarHBondContact O-N 3.1Å
276P97.5Very high98.3Very high37 Ų3751.5 Ų51.524%0.2426%0.26CS..THydrogen-bonded Turntrans-64.5-25.4179.926.4-34.1000113.2E213 V274 R279E213-P276 HydrophobicContact CB-CB 3.88Å; E213-P276 HydrophobicContact CG-CB 4.1Å; V274-P276 WeakPolarHBondContact O-CD 3.39Å; P276-R279 WeakPolarHBondContact O-CB 3.43Å; P276-R279 PolarHBondContact O-N 3.28Å
277E96.6Very high98.2Very high174 Ų17454.4 Ų54.481%0.81327%0.272SS*.THydrogen-bonded Turntrans-74.1-30.5179.2-63.6-170.1176.700112.5D275 R279D275-E277 PolarHBondContact O-N 2.97Å; D275-E277 PolarHBondContact OD1-N 3.4Å; E277-R279 VanDerWaalsContact C-N 3.34Å
278E97.8Very high98.2Very high136 Ų13654.8 Ų54.864%0.63627%0.273SS*.THydrogen-bonded Turntrans-87.2-8176.1-64.7-66.6140.100112.5Q273 D275Q273-E278 HydrophobicContact CG-CB 3.63Å; D275-E278 HydrophobicContact CB-CB 4.2Å; D275-E278 HydrophobicContact CB-CG 4.21Å; D275-E278 PolarHBondContact O-N 3.03Å
279R98.6Very high98.1Very high8 Ų858.1 Ų58.13%0.0330%0.295CS..SBendtrans-76.8137.4179.5-166.1-179.3-60148.86.7109.9E197 E213 L216 L271 Q273 D275 P276 E277 T281E197-R279 IonicContact OE1-CZ 3.7Å; E197-R279 IonicContact OE1-NH1 3.67Å; E197-R279 PolarHBondContact OE1-NH1 2.9Å; E197-R279 IonicContact OE1-NH2 3.37Å; E197-R279 PolarHBondContact OE1-NH2 2.99Å; E197-R279 IonicContact OE2-CZ 3.36Å; E197-R279 IonicContact OE2-NH1 2.71Å; E197-R279 IonicContact OE2-NH2 2.97Å; E197-R279 PolarHBondContact OE2-NH2 3.22Å; E213-R279 PolarHBondContact O-NH1 2.96Å; L216-R279 HydrophobicContact CB-CG 4.44Å; L271-R279 VanDerWaalsContact O-CD 3.24Å; L271-R279 WeakPolarHBondContact O-CD 3.4Å; L271-R279 WeakPolarHBondContact O-CG 3.42Å; L271-R279 PolarHBondContact O-NE 2.94Å; Q273-R279 HydrophobicContact CB-CB 4.14Å; Q273-R279 HydrophobicContact CB-CG 4.36Å; Q273-R279 PolarHBondContact O-NE 3.35Å; Q273-R279 PolarHBondContact O-NH2 3.22Å; D275-R279 PolarHBondContact O-N 3.1Å; P276-R279 WeakPolarHBondContact O-CB 3.43Å; P276-R279 PolarHBondContact O-N 3.28Å; E277-R279 VanDerWaalsContact C-N 3.34Å; R279-T281 PolarHBondContact O-N 3.41Å
280L98.6Very high98Very high30 Ų3056.4 Ų56.416%0.15728%0.283CS..PPolyproline II helixtrans-60.8140.2177.8-65.8174.3000111.5L216 L267 K270 L271 Q284 A285L216-L280 VanDerWaalsContact CG-O 3.29Å; L216-L280 WeakPolarHBondContact CG-O 3.46Å; L267-L280 HydrophobicContact CD1-CD1 4.09Å; K270-L280 HydrophobicContact CB-CD1 3.45Å; K270-L280 VanDerWaalsContact CB-CD1 3.45Å; K270-L280 HydrophobicContact CB-CG 3.73Å; K270-L280 HydrophobicContact CD-CD1 3.98Å; K270-L280 HydrophobicContact CD-CG 4.49Å; K270-L280 HydrophobicContact CG-CD1 4.36Å; K270-L280 PolarHBondContact O-N 3.19Å; L271-L280 HydrophobicContact CD2-CB 4.34Å; L280-Q284 HydrophobicContact CB-CB 4.33Å; L280-Q284 HydrophobicContact CD2-CB 3.9Å; L280-A285 HydrophobicContact CB-CB 4.35Å; L280-A285 HydrophobicContact CD1-CB 4.42Å
281T98.7Very high97.9Very high66 Ų6653 Ų5341%0.40527%0.268SS..PPolyproline II helixtrans-73.3165.3163.2730000110.9R279 E283 Q284 A285R279-T281 PolarHBondContact O-N 3.41Å; T281-E283 VanDerWaalsContact C-N 3.31Å; T281-E283 PolarHBondContact O-N 3.4Å; T281-Q284 PolarHBondContact O-N 3.48Å; T281-Q284 VanDerWaalsContact OG1-CG 3.29Å; T281-Q284 WeakPolarHBondContact OG1-CG 3.36Å; T281-Q284 PolarHBondContact OG1-N 3.4Å; T281-A285 VanDerWaalsContact O-CB 3.31Å; T281-A285 WeakPolarHBondContact O-CB 3.41Å; T281-A285 PolarHBondContact O-N 3.22Å
282A98.4Very high97.4Very high2 Ų258.9 Ų58.92%0.01730%0.296CS..Hα-helixtrans-60.3-41.2177.100000112.2V141 N142 L216 A285 L286V141-A282 HydrophobicContact CG1-CB 4.15Å; N142-A282 HydrophobicContact CB-CB 3.69Å; L216-A282 HydrophobicContact CD1-CB 4.02Å; A282-A285 PolarHBondContact O-N 3.49Å; A282-L286 WeakPolarHBondContact O-CG 3.34Å; A282-L286 PolarHBondContact O-N 3.42Å
283E98Very high95.7Very high114 Ų11468.5 Ų68.553%0.53333%0.332SS..Hα-helixtrans-60.5-48.3175-174.6177.7-171.800112.1N142 T281 A285 L286 Q287N142-E283 PolarHBondContact OD1-N 2.9Å; T281-E283 VanDerWaalsContact C-N 3.31Å; T281-E283 PolarHBondContact O-N 3.4Å; E283-A285 VanDerWaalsContact C-N 3.33Å; E283-A285 PolarHBondContact O-N 2.96Å; E283-L286 PolarHBondContact O-N 3.28Å; E283-Q287 WeakPolarHBondContact O-CG 3.38Å; E283-Q287 PolarHBondContact O-N 2.72Å
284Q98.4Very high93.6Very high95 Ų9571.2 Ų71.244%0.44436%0.358SS..Hα-helixtrans-64.7-39177.7-67.7168.7-17.400111.7L280 T281 Q287 H288L280-Q284 HydrophobicContact CB-CB 4.33Å; L280-Q284 HydrophobicContact CD2-CB 3.9Å; T281-Q284 PolarHBondContact O-N 3.48Å; T281-Q284 VanDerWaalsContact OG1-CG 3.29Å; T281-Q284 WeakPolarHBondContact OG1-CG 3.36Å; T281-Q284 PolarHBondContact OG1-N 3.4Å; Q284-Q287 PolarHBondContact O-N 3.5Å; Q284-H288 PolarHBondContact O-N 2.66Å
285A98.5Very high90.8Very high0 Ų077.5 Ų77.50%038%0.384CS..Hα-helixtrans-63.8-39.9176.600000111.7L138 L267 L271 L280 T281 A282 E283 Q287 H288 F291L138-A285 HydrophobicContact CD1-CB 3.84Å; L138-A285 HydrophobicContact CD2-CB 4.12Å; L267-A285 HydrophobicContact CD1-CB 4.39Å; L271-A285 HydrophobicContact CD2-CB 4.22Å; L280-A285 HydrophobicContact CB-CB 4.35Å; L280-A285 HydrophobicContact CD1-CB 4.42Å; T281-A285 VanDerWaalsContact O-CB 3.31Å; T281-A285 WeakPolarHBondContact O-CB 3.41Å; T281-A285 PolarHBondContact O-N 3.22Å; A282-A285 PolarHBondContact O-N 3.49Å; E283-A285 VanDerWaalsContact C-N 3.33Å; E283-A285 PolarHBondContact O-N 2.96Å; A285-Q287 VanDerWaalsContact C-N 3.26Å; A285-Q287 PolarHBondContact O-N 3.07Å; A285-H288 WeakPolarHBondContact O-CB 3.49Å; A285-H288 PolarHBondContact O-N 2.87Å; A285-H288 VanDerWaalsContact O-N 3.08Å; A285-F291 WeakPolarHBondContact O-CD2 3.43Å; A285-F291 WeakPolarHBondContact O-CE2 3.46Å
286L98Very high88.3Confident41 Ų4176.9 Ų76.922%0.21540%0.395CS..Hα-helixtrans-64.6-29.2175.8-76.3166.9000113.1R135 L138 E139 N142 A282 E283 H288R135-L286 HydrophobicContact CG-CD2 4.02Å; L138-L286 HydrophobicContact CB-CD1 4.39Å; L138-L286 HydrophobicContact CB-CD2 3.73Å; L138-L286 HydrophobicContact CB-CG 3.84Å; E139-L286 HydrophobicContact CG-CD1 4.07Å; E139-L286 HydrophobicContact CG-CD2 3.94Å; N142-L286 HydrophobicContact CB-CD1 4.3Å; A282-L286 WeakPolarHBondContact O-CG 3.34Å; A282-L286 PolarHBondContact O-N 3.42Å; E283-L286 PolarHBondContact O-N 3.28Å; L286-H288 VanDerWaalsContact C-N 3.26Å
287Q97.5Very high85.9Confident129 Ų12981 Ų8160%0.60343%0.425SS*.THydrogen-bonded Turntrans-80.8-4.2174.9-65.1172.31000113.2E283 Q284 A285E283-Q287 WeakPolarHBondContact O-CG 3.38Å; E283-Q287 PolarHBondContact O-N 2.72Å; Q284-Q287 PolarHBondContact O-N 3.5Å; A285-Q287 VanDerWaalsContact C-N 3.26Å; A285-Q287 PolarHBondContact O-N 3.07Å
288H98.1Very high83.5Confident9 Ų981.3 Ų81.34%0.04243%0.426CS..SBendtrans-64.5144-178.8-168.1-92.1000111.9T263 D266 L267 Q284 A285 L286 F290 F291T263-H288 PolarHBondContact O-CE1 3.28Å; D266-H288 IonicContact OD2-CE1 3.82Å; D266-H288 IonicContact OD2-NE2 2.76Å; D266-H288 PolarHBondContact OD2-NE2 3.45Å; L267-H288 HydrophobicContact CD1-CB 3.98Å; Q284-H288 PolarHBondContact O-N 2.66Å; A285-H288 WeakPolarHBondContact O-CB 3.49Å; A285-H288 PolarHBondContact O-N 2.87Å; A285-H288 VanDerWaalsContact O-N 3.08Å; L286-H288 VanDerWaalsContact C-N 3.26Å; H288-F290 WeakPolarHBondContact ND1-CB 2.93Å; H288-F290 PolarHBondContact ND1-N 3.41Å; H288-F290 VanDerWaalsContact ND1-N 3.15Å; H288-F290 PolarHBondContact O-N 2.88Å; H288-F291 HydrophobicContact CB-CD2 4.33Å; H288-F291 PolarHBondContact O-N 3.22Å
289P96.8Very high81.1Confident71 Ų7179.1 Ų79.146%0.46143%0.426SS..THydrogen-bonded Turntrans-56.8-15.8179-28.435.4000115.4T263 F291 E292T263-P289 HydrophobicContact CG2-CB 4.15Å; P289-F291 PolarHBondContact O-N 3.36Å; P289-E292 PolarHBondContact O-N 2.99Å
290F96.8Very high79.1Confident3 Ų388.5 Ų88.51%0.01346%0.461CS..THydrogen-bonded Turntrans-62.9-31.3171.8-179.3-110.4000112.1E127 R131 L223 T263 V264 L267 H288E127-F290 HydrophobicContact CB-CE2 4.47Å; R131-F290 HydrophobicContact CB-CE1 3.76Å; R131-F290 HydrophobicContact CB-CE2 4.49Å; R131-F290 HydrophobicContact CB-CZ 3.7Å; R131-F290 VanDerWaalsContact CD-O 3.27Å; R131-F290 WeakPolarHBondContact CD-O 3.3Å; R131-F290 HydrophobicContact CG-CD1 4.35Å; R131-F290 HydrophobicContact CG-CE1 4Å; R131-F290 HydrophobicContact CG-CZ 4.28Å; R131-F290 PolarHBondContact NE-O 3.41Å; L223-F290 HydrophobicContact CD1-CE1 4.47Å; T263-F290 HydrophobicContact CG2-CB 4.14Å; V264-F290 HydrophobicContact CB-CD2 3.76Å; V264-F290 HydrophobicContact CB-CE2 3.66Å; V264-F290 HydrophobicContact CB-CZ 4.44Å; V264-F290 HydrophobicContact CG2-CD2 3.85Å; V264-F290 HydrophobicContact CG2-CE1 4.37Å; V264-F290 HydrophobicContact CG2-CE2 3.48Å; V264-F290 VanDerWaalsContact CG2-CE2 3.48Å; V264-F290 HydrophobicContact CG2-CG 4.45Å; V264-F290 HydrophobicContact CG2-CZ 3.76Å; L267-F290 HydrophobicContact CD2-CB 3.89Å; L267-F290 HydrophobicContact CD2-CD1 3.52Å; L267-F290 HydrophobicContact CD2-CE1 4.33Å; L267-F290 HydrophobicContact CD2-CG 3.94Å; H288-F290 WeakPolarHBondContact ND1-CB 2.93Å; H288-F290 PolarHBondContact ND1-N 3.41Å; H288-F290 VanDerWaalsContact ND1-N 3.15Å; H288-F290 PolarHBondContact O-N 2.88Å
291F95.7Very high77.1Confident10 Ų1094.2 Ų94.24%0.04449%0.492CS..THydrogen-bonded Turntrans-98.4-3.8-179.4-60.9-70.3000114.1R131 M134 R135 L138 L267 A285 H288 P289 R293R131-F291 HydrophobicContact CG-CD1 3.86Å; R131-F291 HydrophobicContact CG-CE1 4.29Å; M134-F291 HydrophobicContact CB-CE1 3.99Å; M134-F291 HydrophobicContact CB-CZ 3.97Å; R135-F291 HydrophobicContact CB-CD1 3.85Å; R135-F291 HydrophobicContact CB-CE1 3.91Å; R135-F291 HydrophobicContact CG-CD1 4.47Å; R135-F291 PolarHBondContact NH2-O 2.95Å; L138-F291 HydrophobicContact CD1-CE2 3.54Å; L138-F291 HydrophobicContact CD1-CZ 3.47Å; L138-F291 VanDerWaalsContact CD1-CZ 3.47Å; L267-F291 HydrophobicContact CD2-CD2 4.48Å; L267-F291 HydrophobicContact CD2-CE2 3.61Å; L267-F291 HydrophobicContact CD2-CZ 3.93Å; A285-F291 WeakPolarHBondContact O-CD2 3.43Å; A285-F291 WeakPolarHBondContact O-CE2 3.46Å; H288-F291 HydrophobicContact CB-CD2 4.33Å; H288-F291 PolarHBondContact O-N 3.22Å; P289-F291 PolarHBondContact O-N 3.36Å; F291-R293 PolarHBondContact O-N 3.5Å
292E88.3Confident75.8Confident123 Ų12392.9 Ų92.958%0.57548%0.482SS*.SBendtrans-60.6136.2172-73174.2-17100110.3P289 C294P289-E292 PolarHBondContact O-N 2.99Å; E292-C294 PolarHBondContact O-N 2.86Å
293R63.3Low74.8Confident207 Ų20796 Ų9678%0.78150%0.502SS*.  trans-67.3127.9168.9-76.4-179.4175.2169.10.5106.8F291 E295F291-R293 PolarHBondContact O-N 3.5Å; R293-E295 HydrophobicContact CB-CG 4.31Å; R293-E295 PolarHBondContact O-N 3.04Å
294C53.2Low73.8Confident133 Ų13396 Ų9690%0.89951%0.511SS*.  trans-66.375.6165.7-72.70000109.4E292 G296E292-C294 PolarHBondContact O-N 2.86Å; C294-G296 PolarHBondContact O-N 3.38Å
295E41Very low72.4Confident168 Ų168100.9 Ų100.979%0.78553%0.525SS*.  trans-7798.8162.7-71.9-170.9179.100107.4R293R293-E295 HydrophobicContact CB-CG 4.31Å; R293-E295 PolarHBondContact O-N 3.04Å
296G44.1Very low71.2Confident58 Ų58104.5 Ų104.560%0.59854%0.542SS*.SBendtrans84.1117.6167.900000114.9C294 Q298C294-G296 PolarHBondContact O-N 3.38Å; G296-Q298 PolarHBondContact O-N 3.3Å
297S47.9Very low70.3Confident124 Ų124108.2 Ų108.287%0.86756%0.557SS**  trans-1490.3152167.80000115.3
298Q46.7Very low69.4Low180 Ų180109 Ų10984%0.84156%0.559SS**  trans-83.4138154.2-75.3-169-0.800108.8G296 W300G296-Q298 PolarHBondContact O-N 3.3Å; Q298-W300 PolarHBondContact O-N 3.46Å
299S46.7Very low68.5Low91 Ų91112.2 Ų112.264%0.63657%0.57SS**  trans-51.2126.4-179.753.50000111N301S299-N301 PolarHBondContact O-N 3.29Å
300W56.5Low67.8Low205 Ų205111.8 Ų111.878%0.77757%0.566SS**  trans-50.492.4177.3-64.481.1000112.4Q298 L302Q298-W300 PolarHBondContact O-N 3.46Å; W300-L302 HydrophobicContact CB-CD1 4.1Å; W300-L302 HydrophobicContact CB-CG 4.1Å; W300-L302 HydrophobicContact CE3-CD1 4.4Å; W300-L302 HydrophobicContact CE3-CD2 4.14Å; W300-L302 HydrophobicContact CE3-CG 4.36Å; W300-L302 PolarHBondContact O-N 2.64Å
301N57.2Low67.3Low149 Ų149113.9 Ų113.980%0.79758%0.584SS**  trans-80.166.9170.2-82.7-26.4000109.7S299S299-N301 PolarHBondContact O-N 3.29Å
302L69.8Low66.8Low38 Ų38115.8 Ų115.820%0.19960%0.596CS.*  trans-72.2131.9176.7-67.1161.8000109.8W300 Q306 K307 V310W300-L302 HydrophobicContact CB-CD1 4.1Å; W300-L302 HydrophobicContact CB-CG 4.1Å; W300-L302 HydrophobicContact CE3-CD1 4.4Å; W300-L302 HydrophobicContact CE3-CD2 4.14Å; W300-L302 HydrophobicContact CE3-CG 4.36Å; W300-L302 PolarHBondContact O-N 2.64Å; L302-Q306 HydrophobicContact CB-CB 4.05Å; L302-Q306 HydrophobicContact CD2-CB 3.81Å; L302-K307 HydrophobicContact CB-CB 4.43Å; L302-K307 HydrophobicContact CB-CD 4.39Å; L302-K307 HydrophobicContact CB-CG 3.4Å; L302-K307 VanDerWaalsContact CB-CG 3.4Å; L302-K307 HydrophobicContact CD1-CG 4.35Å; L302-K307 WeakPolarHBondContact O-CD 3.37Å; L302-K307 WeakPolarHBondContact O-CE 3.49Å; L302-K307 WeakPolarHBondContact O-CG 3.45Å; L302-V310 HydrophobicContact CD1-CB 4.29Å; L302-V310 HydrophobicContact CD1-CG1 4.44Å; L302-V310 HydrophobicContact CD1-CG2 3.97Å; L302-V310 HydrophobicContact CD2-CG2 4.13Å
303T79.2Confident66.5Low69 Ų69117.1 Ų117.142%0.42360%0.596SS.*  trans-58.6157.9168.359.20000110.6R305 Q306 K307T303-R305 PolarHBondContact O-N 2.84Å; T303-R305 VanDerWaalsContact O-N 3.12Å; T303-Q306 CarbonylContact O-C 3.53Å; T303-Q306 WeakPolarHBondContact O-CA 3.21Å; T303-Q306 PolarHBondContact O-N 3.09Å; T303-Q306 WeakPolarHBondContact OG1-CB 3.27Å; T303-Q306 WeakPolarHBondContact OG1-CG 3.29Å; T303-Q306 PolarHBondContact OG1-N 3.44Å; T303-Q306 PolarHBondContact OG1-OE1 2.99Å; T303-K307 PolarHBondContact O-N 2.82Å
304P75.3Confident67.6Low112 Ų112111.2 Ų111.273%0.72758%0.583SS**Hα-helixtrans-52.9-37.3178.3-27.835.3000113.4K307 F308P304-K307 PolarHBondContact O-N 3.2Å; P304-F308 WeakPolarHBondContact O-CB 3.35Å; P304-F308 PolarHBondContact O-N 3.45Å
305R69.1Low69.2Low198 Ų198110.7 Ų110.775%0.74757%0.57SS**Hα-helixtrans-68.9-40.6175.5-166.7175.3-178.8177.4-1.8112.2T303 F308 R309T303-R305 PolarHBondContact O-N 2.84Å; T303-R305 VanDerWaalsContact O-N 3.12Å; R305-F308 PolarHBondContact O-N 2.9Å; R305-R309 WeakPolarHBondContact O-CB 3.49Å; R305-R309 VanDerWaalsContact O-CG 3.3Å; R305-R309 WeakPolarHBondContact O-CG 3.32Å; R305-R309 PolarHBondContact O-N 3.35Å
306Q74.1Confident71Confident77 Ų77107 Ų10736%0.3656%0.555SS.*Hα-helixtrans-70.3-37.3174.3-71.7163.5-27.700112.1L302 T303 R309 V310L302-Q306 HydrophobicContact CB-CB 4.05Å; L302-Q306 HydrophobicContact CD2-CB 3.81Å; T303-Q306 CarbonylContact O-C 3.53Å; T303-Q306 WeakPolarHBondContact O-CA 3.21Å; T303-Q306 PolarHBondContact O-N 3.09Å; T303-Q306 WeakPolarHBondContact OG1-CB 3.27Å; T303-Q306 WeakPolarHBondContact OG1-CG 3.29Å; T303-Q306 PolarHBondContact OG1-N 3.44Å; T303-Q306 PolarHBondContact OG1-OE1 2.99Å; Q306-R309 PolarHBondContact O-N 2.8Å; Q306-V310 WeakPolarHBondContact O-CB 3.27Å; Q306-V310 VanDerWaalsContact O-CG2 3.24Å; Q306-V310 WeakPolarHBondContact O-CG2 3.34Å; Q306-V310 PolarHBondContact O-N 3Å
307K78.4Confident72.7Confident119 Ų119106.4 Ų106.452%0.51755%0.545SS..Hα-helixtrans-61.3-45.1172.1-73.9179.6173.2167.50110.7L302 T303 P304 V310 A311L302-K307 HydrophobicContact CB-CB 4.43Å; L302-K307 HydrophobicContact CB-CD 4.39Å; L302-K307 HydrophobicContact CB-CG 3.4Å; L302-K307 VanDerWaalsContact CB-CG 3.4Å; L302-K307 HydrophobicContact CD1-CG 4.35Å; L302-K307 WeakPolarHBondContact O-CD 3.37Å; L302-K307 WeakPolarHBondContact O-CE 3.49Å; L302-K307 WeakPolarHBondContact O-CG 3.45Å; T303-K307 PolarHBondContact O-N 2.82Å; P304-K307 PolarHBondContact O-N 3.2Å; K307-V310 PolarHBondContact O-N 2.89Å; K307-A311 VanDerWaalsContact O-CB 3.26Å; K307-A311 WeakPolarHBondContact O-CB 3.43Å; K307-A311 PolarHBondContact O-N 3.18Å
308F80.3Confident74.4Confident146 Ų146103.3 Ų103.364%0.6453%0.527SS*.Hα-helixtrans-62.7-45.5174.6-177.5-102.6000111.4P304 R305 A311 V312P304-F308 WeakPolarHBondContact O-CB 3.35Å; P304-F308 PolarHBondContact O-N 3.45Å; R305-F308 PolarHBondContact O-N 2.9Å; F308-A311 PolarHBondContact O-N 3.22Å; F308-V312 HydrophobicContact CD1-CG2 4.15Å; F308-V312 HydrophobicContact CE1-CG2 3.8Å; F308-V312 HydrophobicContact CE2-CG2 4.19Å; F308-V312 HydrophobicContact CZ-CG2 3.82Å; F308-V312 WeakPolarHBondContact O-CB 3.29Å; F308-V312 VanDerWaalsContact O-CG2 3.24Å; F308-V312 WeakPolarHBondContact O-CG2 3.49Å; F308-V312 PolarHBondContact O-N 3.12Å
309R78.6Confident75.8Confident75 Ų7596 Ų9628%0.28350%0.5SS..Hα-helixtrans-61.1-48.2175-76.1-17968.6166.42.2111.3D258 D259 R305 Q306 A311 V312 W313D258-R309 PolarHBondContact O-NH1 3.37Å; D259-R309 IonicContact OD1-CZ 3.47Å; D259-R309 IonicContact OD1-NH1 2.7Å; D259-R309 IonicContact OD1-NH2 2.67Å; D259-R309 PolarHBondContact OD1-NH2 2.74Å; R305-R309 WeakPolarHBondContact O-CB 3.49Å; R305-R309 VanDerWaalsContact O-CG 3.3Å; R305-R309 WeakPolarHBondContact O-CG 3.32Å; R305-R309 PolarHBondContact O-N 3.35Å; Q306-R309 PolarHBondContact O-N 2.8Å; R309-A311 VanDerWaalsContact C-N 3.34Å; R309-A311 PolarHBondContact O-N 3.4Å; R309-V312 CarbonylContact O-C 3.52Å; R309-V312 PolarHBondContact O-N 2.82Å; R309-W313 WeakPolarHBondContact O-CB 3.26Å; R309-W313 PolarHBondContact O-N 3.4Å
310V82.7Confident76.8Confident63 Ų63100.2 Ų100.238%0.38250%0.502SS..Hα-helixtrans-61.4-43177.3170.90000110.3L302 Q306 K307 V312 W313 T314L302-V310 HydrophobicContact CD1-CB 4.29Å; L302-V310 HydrophobicContact CD1-CG1 4.44Å; L302-V310 HydrophobicContact CD1-CG2 3.97Å; L302-V310 HydrophobicContact CD2-CG2 4.13Å; Q306-V310 WeakPolarHBondContact O-CB 3.27Å; Q306-V310 VanDerWaalsContact O-CG2 3.24Å; Q306-V310 WeakPolarHBondContact O-CG2 3.34Å; Q306-V310 PolarHBondContact O-N 3Å; K307-V310 PolarHBondContact O-N 2.89Å; V310-V312 PolarHBondContact O-N 2.9Å; V310-W313 CarbonylContact O-C 3.37Å; V310-W313 PolarHBondContact O-N 3.44Å; V310-T314 VanDerWaalsContact O-CB 3.27Å; V310-T314 WeakPolarHBondContact O-CB 3.41Å; V310-T314 PolarHBondContact O-N 3.21Å; V310-T314 PolarHBondContact O-OG1 2.89Å
311A84.9Confident77.6Confident47 Ų4795.4 Ų95.439%0.38850%0.495SS..Hα-helixtrans-60.9-45.8174.900000111.9K307 F308 R309 W313 T314 I315K307-A311 VanDerWaalsContact O-CB 3.26Å; K307-A311 WeakPolarHBondContact O-CB 3.43Å; K307-A311 PolarHBondContact O-N 3.18Å; F308-A311 PolarHBondContact O-N 3.22Å; R309-A311 VanDerWaalsContact C-N 3.34Å; R309-A311 PolarHBondContact O-N 3.4Å; A311-W313 VanDerWaalsContact C-N 3.34Å; A311-W313 PolarHBondContact O-N 3.25Å; A311-T314 PolarHBondContact O-N 3.5Å; A311-I315 WeakPolarHBondContact O-CB 3.33Å; A311-I315 WeakPolarHBondContact O-CD1 3.18Å; A311-I315 WeakPolarHBondContact O-CG1 3.45Å; A311-I315 PolarHBondContact O-N 2.91Å
312V86.1Confident78.3Confident50 Ų5091.7 Ų91.730%0.30349%0.486SS..Hα-helixtrans-61.1-43.5174.4168.70000110.6F308 R309 V310 I315 L316F308-V312 HydrophobicContact CD1-CG2 4.15Å; F308-V312 HydrophobicContact CE1-CG2 3.8Å; F308-V312 HydrophobicContact CE2-CG2 4.19Å; F308-V312 HydrophobicContact CZ-CG2 3.82Å; F308-V312 WeakPolarHBondContact O-CB 3.29Å; F308-V312 VanDerWaalsContact O-CG2 3.24Å; F308-V312 WeakPolarHBondContact O-CG2 3.49Å; F308-V312 PolarHBondContact O-N 3.12Å; R309-V312 CarbonylContact O-C 3.52Å; R309-V312 PolarHBondContact O-N 2.82Å; V310-V312 PolarHBondContact O-N 2.9Å; V312-I315 PolarHBondContact O-N 2.68Å; V312-L316 HydrophobicContact CG1-CD1 3.65Å; V312-L316 HydrophobicContact CG1-CG 4.19Å; V312-L316 WeakPolarHBondContact O-CB 3.38Å; V312-L316 WeakPolarHBondContact O-CG 3.48Å; V312-L316 PolarHBondContact O-N 2.92Å
313W81.4Confident77.7Confident150 Ų15095 Ų9557%0.56850%0.503SS*.Hα-helixtrans-70.4-37179.9-77.850.4000111.9R309 V310 A311 L316 A317R309-W313 WeakPolarHBondContact O-CB 3.26Å; R309-W313 PolarHBondContact O-N 3.4Å; V310-W313 CarbonylContact O-C 3.37Å; V310-W313 PolarHBondContact O-N 3.44Å; A311-W313 VanDerWaalsContact C-N 3.34Å; A311-W313 PolarHBondContact O-N 3.25Å; W313-L316 CarbonylContact O-C 3.48Å; W313-L316 PolarHBondContact O-N 3.35Å; W313-A317 WeakPolarHBondContact O-CA 3.29Å; W313-A317 WeakPolarHBondContact O-CB 3.44Å; W313-A317 PolarHBondContact O-N 3.37Å
314T86.1Confident76.3Confident83 Ų8395.8 Ų95.851%0.50951%0.511SS..Hα-helixtrans-67.8-42.1174.5-610000110.3V310 A311 A317 A318V310-T314 VanDerWaalsContact O-CB 3.27Å; V310-T314 WeakPolarHBondContact O-CB 3.41Å; V310-T314 PolarHBondContact O-N 3.21Å; V310-T314 PolarHBondContact O-OG1 2.89Å; A311-T314 PolarHBondContact O-N 3.5Å; T314-A317 PolarHBondContact O-N 3.33Å; T314-A318 WeakPolarHBondContact O-CB 3.23Å; T314-A318 PolarHBondContact O-N 3.3Å
315I87.3Confident75.2Confident123 Ų12396.1 Ų96.163%0.63151%0.511SS*.Hα-helixtrans-67.1-41.2173.6-68.7166.1000110.6A311 V312 A317 G319A311-I315 WeakPolarHBondContact O-CB 3.33Å; A311-I315 WeakPolarHBondContact O-CD1 3.18Å; A311-I315 WeakPolarHBondContact O-CG1 3.45Å; A311-I315 PolarHBondContact O-N 2.91Å; V312-I315 PolarHBondContact O-N 2.68Å; I315-A317 VanDerWaalsContact C-N 3.35Å; I315-G319 WeakPolarHBondContact O-CA 3.46Å; I315-G319 PolarHBondContact O-N 3.5Å
316L78.8Confident74.5Confident89 Ų8993.9 Ų93.947%0.46651%0.509SS..Hα-helixtrans-69.5-32.5175.9-73173.2000111.8V312 W313 R320V312-L316 HydrophobicContact CG1-CD1 3.65Å; V312-L316 HydrophobicContact CG1-CG 4.19Å; V312-L316 WeakPolarHBondContact O-CB 3.38Å; V312-L316 WeakPolarHBondContact O-CG 3.48Å; V312-L316 PolarHBondContact O-N 2.92Å; W313-L316 CarbonylContact O-C 3.48Å; W313-L316 PolarHBondContact O-N 3.35Å; L316-R320 WeakPolarHBondContact O-CA 3.29Å; L316-R320 WeakPolarHBondContact O-CB 3.24Å; L316-R320 WeakPolarHBondContact O-CD 3.45Å; L316-R320 WeakPolarHBondContact O-CG 3.32Å; L316-R320 PolarHBondContact O-N 3.14Å
317A79.9Confident73.1Confident47 Ų47100.3 Ų100.339%0.38853%0.53SS..Hα-helixtrans-77.3-47.1177.500000110.7W313 T314 I315 G319 R320 V321W313-A317 WeakPolarHBondContact O-CA 3.29Å; W313-A317 WeakPolarHBondContact O-CB 3.44Å; W313-A317 PolarHBondContact O-N 3.37Å; T314-A317 PolarHBondContact O-N 3.33Å; I315-A317 VanDerWaalsContact C-N 3.35Å; A317-G319 VanDerWaalsContact C-N 3.29Å; A317-G319 PolarHBondContact O-N 3.27Å; A317-R320 CarbonylContact O-C 3.53Å; A317-R320 WeakPolarHBondContact O-CA 3.47Å; A317-R320 PolarHBondContact O-N 2.72Å; A317-R320 VanDerWaalsContact O-N 3.12Å; A317-V321 WeakPolarHBondContact O-CB 3.03Å; A317-V321 VanDerWaalsContact O-CG2 3.24Å; A317-V321 WeakPolarHBondContact O-CG2 3.46Å; A317-V321 PolarHBondContact O-N 3.23Å
318A83.6Confident71.5Confident59 Ų59102.7 Ų102.749%0.48855%0.547SS..Hα-helixtrans-60.5-41.9171.400000110.7T314 V321 A322T314-A318 WeakPolarHBondContact O-CB 3.23Å; T314-A318 PolarHBondContact O-N 3.3Å; A318-V321 PolarHBondContact O-N 3.49Å; A318-A322 WeakPolarHBondContact O-CB 3.44Å; A318-A322 PolarHBondContact O-N 3.34Å
319G75.4Confident70.1Confident27 Ų27107 Ų10728%0.27856%0.559SS.*Hα-helixtrans-62.4-43.7170.600000111.8I315 A317 V321 L323I315-G319 WeakPolarHBondContact O-CA 3.46Å; I315-G319 PolarHBondContact O-N 3.5Å; A317-G319 VanDerWaalsContact C-N 3.29Å; A317-G319 PolarHBondContact O-N 3.27Å; G319-V321 PolarHBondContact O-N 2.91Å; G319-L323 WeakPolarHBondContact O-CA 3.47Å; G319-L323 WeakPolarHBondContact O-CB 3.12Å; G319-L323 WeakPolarHBondContact O-CD1 3.31Å; G319-L323 WeakPolarHBondContact O-CG 3.43Å; G319-L323 PolarHBondContact O-N 3.01Å
320R67.8Low69Low178 Ų178108.1 Ų108.167%0.67258%0.576SS**Hα-helixtrans-67.3-31.1175.1-82.8169.3-173.5179.83.9113L316 A317 L323 S324L316-R320 WeakPolarHBondContact O-CA 3.29Å; L316-R320 WeakPolarHBondContact O-CB 3.24Å; L316-R320 WeakPolarHBondContact O-CD 3.45Å; L316-R320 WeakPolarHBondContact O-CG 3.32Å; L316-R320 PolarHBondContact O-N 3.14Å; A317-R320 CarbonylContact O-C 3.53Å; A317-R320 WeakPolarHBondContact O-CA 3.47Å; A317-R320 PolarHBondContact O-N 2.72Å; A317-R320 VanDerWaalsContact O-N 3.12Å; R320-L323 CarbonylContact O-C 3.54Å; R320-S324 WeakPolarHBondContact O-CA 3.42Å; R320-S324 WeakPolarHBondContact O-CB 3.42Å; R320-S324 PolarHBondContact O-N 2.92Å
321V72.8Confident67.9Low104 Ų104110.5 Ų110.563%0.6359%0.586SS**Hα-helixtrans-79.2-43.8177.4168.40000110A317 A318 G319 L323 S324A317-V321 WeakPolarHBondContact O-CB 3.03Å; A317-V321 VanDerWaalsContact O-CG2 3.24Å; A317-V321 WeakPolarHBondContact O-CG2 3.46Å; A317-V321 PolarHBondContact O-N 3.23Å; A318-V321 PolarHBondContact O-N 3.49Å; G319-V321 PolarHBondContact O-N 2.91Å; V321-L323 VanDerWaalsContact C-N 3.27Å; V321-L323 PolarHBondContact O-N 2.8Å; V321-S324 VanDerWaalsContact O-CB 3.32Å; V321-S324 WeakPolarHBondContact O-CB 3.34Å; V321-S324 PolarHBondContact O-N 3.08Å
322A72.4Confident67.2Low72 Ų72112 Ų11260%0.59559%0.591SS**Hα-helixtrans-65.4-30.9172.700000112.4A318 T325A318-A322 WeakPolarHBondContact O-CB 3.44Å; A318-A322 PolarHBondContact O-N 3.34Å; A322-T325 PolarHBondContact O-OG1 3.46Å
323L58.5Low66.3Low108 Ų108117.6 Ų117.657%0.56561%0.611SS**THydrogen-bonded Turntrans-93.8-0.3169.3-60.3165.1000111.8G319 R320 V321 T325 H326 R327G319-L323 WeakPolarHBondContact O-CA 3.47Å; G319-L323 WeakPolarHBondContact O-CB 3.12Å; G319-L323 WeakPolarHBondContact O-CD1 3.31Å; G319-L323 WeakPolarHBondContact O-CG 3.43Å; G319-L323 PolarHBondContact O-N 3.01Å; R320-L323 CarbonylContact O-C 3.54Å; V321-L323 VanDerWaalsContact C-N 3.27Å; V321-L323 PolarHBondContact O-N 2.8Å; L323-T325 VanDerWaalsContact C-N 3.3Å; L323-H326 CarbonylContact O-C 3.56Å; L323-H326 WeakPolarHBondContact O-CA 3.44Å; L323-H326 PolarHBondContact O-N 3.5Å; L323-R327 PolarHBondContact O-N 3.43Å; L323-R327 VanDerWaalsContact O-N 3.12Å
324S49.7Very low65.8Low85 Ų85116.7 Ų116.759%0.59462%0.617SS**THydrogen-bonded Turntrans-79.2-23.4177.21730000110.2R320 V321 H326R320-S324 WeakPolarHBondContact O-CA 3.42Å; R320-S324 WeakPolarHBondContact O-CB 3.42Å; R320-S324 PolarHBondContact O-N 2.92Å; V321-S324 VanDerWaalsContact O-CB 3.32Å; V321-S324 WeakPolarHBondContact O-CB 3.34Å; V321-S324 PolarHBondContact O-N 3.08Å; S324-H326 PolarHBondContact O-N 3.35Å
325T51.4Low64.9Low118 Ų118115.3 Ų115.372%0.72461%0.611SS**SBendtrans-67.1-18.2163.8530000111.1A322 L323A322-T325 PolarHBondContact O-OG1 3.46Å; L323-T325 VanDerWaalsContact C-N 3.3Å
326H54.5Low64.1Low151 Ų151112.5 Ų112.570%0.69960%0.597SS**SBendtrans-146.681.8177.3-93.30.9000113.3L323 S324L323-H326 CarbonylContact O-C 3.56Å; L323-H326 WeakPolarHBondContact O-CA 3.44Å; L323-H326 PolarHBondContact O-N 3.5Å; S324-H326 PolarHBondContact O-N 3.35Å
327R45.2Very low63.9Low213 Ų213114.4 Ų114.480%0.80461%0.607SS**  trans100.7108.3167.4-53.5177.3-170.7-144.93.2116.6L323 R329L323-R327 PolarHBondContact O-N 3.43Å; L323-R327 VanDerWaalsContact O-N 3.12Å; R327-R329 PolarHBondContact O-N 3.4Å
328L44.7Very low63.9Low168 Ų168123.1 Ų123.188%0.8863%0.63SS**  trans-52.1118.9133.4-75.9156.7000106.9P330L328-P330 WeakPolarHBondContact O-CD 3.35Å; L328-P330 VanDerWaalsContact O-N 3.1Å
329R50.5Low63.4Low238 Ų238124.2 Ų124.290%0.89863%0.627SS**  trans-62.4113.8166.7-89.2-171.9-178.3-1760.9106.6R327 L331R327-R329 PolarHBondContact O-N 3.4Å; R329-L331 PolarHBondContact O-N 3.28Å
330P56.3Low63.3Low97 Ų97124.7 Ų124.763%0.6363%0.625SS**  trans-63.3140.4176.926.3-31.3000108.3L328 T332L328-P330 WeakPolarHBondContact O-CD 3.35Å; L328-P330 VanDerWaalsContact O-N 3.1Å; P330-T332 PolarHBondContact O-N 3.29Å
331L59.1Low63.5Low113 Ų113120.7 Ų120.759%0.59261%0.611SS**  trans-51.4108.1165.5-92120.7000107.7R329 K333 L336 L343 V346R329-L331 PolarHBondContact O-N 3.28Å; L331-K333 PolarHBondContact O-N 2.81Å; L331-L336 HydrophobicContact CB-CD1 4.21Å; L331-L336 HydrophobicContact CD2-CD1 3.96Å; L331-L336 HydrophobicContact CD2-CD2 3.78Å; L331-L336 HydrophobicContact CD2-CG 3.82Å; L331-L343 HydrophobicContact CD2-CD1 4.21Å; L331-V346 HydrophobicContact CD2-CG2 3.74Å
332T68.8Low63.3Low80 Ų80118.6 Ų118.649%0.49161%0.605SS.*  trans-71.6130.3179.2280000108.9P330 N334 S335 L336P330-T332 PolarHBondContact O-N 3.29Å; T332-N334 PolarHBondContact O-N 3.3Å; T332-S335 WeakPolarHBondContact O-CB 3.32Å; T332-S335 PolarHBondContact O-N 2.87Å; T332-S335 PolarHBondContact OG1-OG 2.76Å; T332-L336 PolarHBondContact O-N 2.99Å
333K68.4Low63.1Low167 Ų167118.4 Ų118.473%0.72659%0.593SS**Hα-helixtrans-49.2-37.5179.3-156.1178.9-176.8-178.80112.1L331 S335 L336 L337L331-K333 PolarHBondContact O-N 2.81Å; K333-S335 PolarHBondContact O-N 3.39Å; K333-L336 PolarHBondContact O-N 3.42Å; K333-L337 HydrophobicContact CG-CD1 4.08Å; K333-L337 WeakPolarHBondContact O-CB 3.48Å; K333-L337 VanDerWaalsContact O-CG 3.26Å; K333-L337 WeakPolarHBondContact O-CG 3.44Å; K333-L337 PolarHBondContact O-N 2.92Å
334N71.5Confident63.3Low130 Ų130117.8 Ų117.870%0.69558%0.583SS**Hα-helixtrans-64.8-32.7176.9-74.3-8.3000114.3T332 R338T332-N334 PolarHBondContact O-N 3.3Å; N334-R338 WeakPolarHBondContact O-CB 3.43Å; N334-R338 PolarHBondContact O-N 3.16Å; N334-R338 VanDerWaalsContact O-N 3.14Å
335S66Low64.1Low55 Ų55118.2 Ų118.239%0.38558%0.584SS.*Hα-helixtrans-74.1-37.8178.6-54.70000111.5T332 K333 D339T332-S335 WeakPolarHBondContact O-CB 3.32Å; T332-S335 PolarHBondContact O-N 2.87Å; T332-S335 PolarHBondContact OG1-OG 2.76Å; K333-S335 PolarHBondContact O-N 3.39Å; S335-D339 PolarHBondContact O-N 3.22Å
336L70.4Confident65.3Low63 Ų63113.6 Ų113.633%0.3356%0.556SS.*Hα-helixtrans-68.1-36.3173.4-78.1167.4000112.7L331 T332 K333 P340 V346L331-L336 HydrophobicContact CB-CD1 4.21Å; L331-L336 HydrophobicContact CD2-CD1 3.96Å; L331-L336 HydrophobicContact CD2-CD2 3.78Å; L331-L336 HydrophobicContact CD2-CG 3.82Å; T332-L336 PolarHBondContact O-N 2.99Å; K333-L336 PolarHBondContact O-N 3.42Å; L336-P340 WeakPolarHBondContact O-CB 3.26Å; L336-P340 VanDerWaalsContact O-CD 3.31Å; L336-P340 WeakPolarHBondContact O-CD 3.35Å; L336-V346 HydrophobicContact CD2-CB 4.33Å; L336-V346 HydrophobicContact CD2-CG1 3.6Å; L336-V346 HydrophobicContact CD2-CG2 3.8Å
337L74.4Confident66.4Low129 Ų129109.2 Ų109.268%0.67553%0.533SS*.Hα-helixtrans-76.9-29.1-179-73.5169000113.4K333K333-L337 HydrophobicContact CG-CD1 4.08Å; K333-L337 WeakPolarHBondContact O-CB 3.48Å; K333-L337 VanDerWaalsContact O-CG 3.26Å; K333-L337 WeakPolarHBondContact O-CG 3.44Å; K333-L337 PolarHBondContact O-N 2.92Å
338R80.4Confident67.5Low231 Ų231103.8 Ų103.887%0.87251%0.512SS*.Hα-helixtrans-81.4-49.4-175.2-173.1-179.7178.9-168.4-0.3112.9N334N334-R338 WeakPolarHBondContact O-CB 3.43Å; N334-R338 PolarHBondContact O-N 3.16Å; N334-R338 VanDerWaalsContact O-N 3.14Å
339D73.1Confident68.9Low81 Ų81101.2 Ų101.243%0.43350%0.499SS..  trans-155.484.3178.6-173.4-6.8000109.7S335 Y341 A342S335-D339 PolarHBondContact O-N 3.22Å; D339-Y341 PolarHBondContact O-N 3.37Å; D339-Y341 PolarHBondContact OD1-N 2.79Å; D339-Y341 VanDerWaalsContact OD1-N 3.12Å; D339-A342 HydrophobicContact CB-CB 4.13Å; D339-A342 PolarHBondContact O-N 3.37Å; D339-A342 PolarHBondContact OD1-N 2.97Å; D339-A342 WeakPolarHBondContact OD2-CB 3.44Å
340P72.8Confident70.4Confident37 Ų3792.3 Ų92.324%0.2447%0.469CS..SBendtrans-66.5-24.1179.124.9-29.8000112.2L336 V346 I350L336-P340 WeakPolarHBondContact O-CB 3.26Å; L336-P340 VanDerWaalsContact O-CD 3.31Å; L336-P340 WeakPolarHBondContact O-CD 3.35Å; P340-V346 HydrophobicContact CB-CG1 4.15Å; P340-I350 HydrophobicContact CB-CD1 3.76Å; P340-I350 HydrophobicContact CG-CD1 4.36Å
341Y71.6Confident71.1Confident95 Ų9588.6 Ų88.637%0.37344%0.444SS..THydrogen-bonded Turntrans-77-25.8179.5-76.6-90.6000111.9D339 L343 R347 I350D339-Y341 PolarHBondContact O-N 3.37Å; D339-Y341 PolarHBondContact OD1-N 2.79Å; D339-Y341 VanDerWaalsContact OD1-N 3.12Å; Y341-L343 PolarHBondContact O-N 2.71Å; Y341-L343 VanDerWaalsContact O-N 3.16Å; Y341-R347 HydrophobicContact CD1-CG 3.85Å; Y341-R347 HydrophobicContact CE1-CG 4.45Å; Y341-R347 PolarHBondContact O-NE 2.87Å; Y341-R347 PolarHBondContact O-NH2 3.27Å; Y341-I350 HydrophobicContact CE1-CG2 4.24Å; Y341-I350 WeakPolarHBondContact OH-CG2 3.32Å
342A69.1Low71.6Confident60 Ų6085.1 Ų85.150%0.49643%0.426SS..THydrogen-bonded Turntrans-59.9-26174.600000114.1D339D339-A342 HydrophobicContact CB-CB 4.13Å; D339-A342 PolarHBondContact O-N 3.37Å; D339-A342 PolarHBondContact OD1-N 2.97Å; D339-A342 WeakPolarHBondContact OD2-CB 3.44Å
343L69.4Low72Confident68 Ų6884.1 Ų84.136%0.35642%0.421SS..SBendtrans-93.2105.9-176.7-64.3175.9000111.2L331 Y341 P345 V346 R347L331-L343 HydrophobicContact CD2-CD1 4.21Å; Y341-L343 PolarHBondContact O-N 2.71Å; Y341-L343 VanDerWaalsContact O-N 3.16Å; L343-P345 VanDerWaalsContact C-CD 3.45Å; L343-P345 VanDerWaalsContact C-N 3.35Å; L343-P345 VanDerWaalsContact O-N 3.13Å; L343-V346 HydrophobicContact CB-CB 3.99Å; L343-V346 HydrophobicContact CB-CG2 3.89Å; L343-V346 HydrophobicContact CD1-CG2 4.07Å; L343-V346 PolarHBondContact O-N 2.76Å; L343-R347 PolarHBondContact O-N 2.84Å
344R62.8Low72.2Confident94 Ų9477.7 Ų77.736%0.35540%0.399SS..Hα-helixtrans-46.9-43.1-177.9-163.9179.9-172.1178.55.9115.2D259 R348D259-R344 IonicContact OD2-CZ 3.99Å; D259-R344 IonicContact OD2-NH1 2.79Å; D259-R344 PolarHBondContact OD2-NH1 3.02Å; R344-R348 WeakPolarHBondContact O-CG 3.36Å; R344-R348 PolarHBondContact O-N 3Å; R344-R348 VanDerWaalsContact O-N 3.13Å
345P66.1Low71.8Confident94 Ų9473.7 Ų73.761%0.6138%0.376SS*.Hα-helixtrans-69.2-36.7177.5-19.333.2000113.6L343 L349L343-P345 VanDerWaalsContact C-CD 3.45Å; L343-P345 VanDerWaalsContact C-N 3.35Å; L343-P345 VanDerWaalsContact O-N 3.13Å; P345-L349 PolarHBondContact O-N 3.2Å
346V76.6Confident72Confident21 Ų2180.5 Ų80.513%0.12739%0.393CS..Hα-helixtrans-72.8-44.1178.7179.40000109.9L331 L336 P340 L343 R348 L349 I350L331-V346 HydrophobicContact CD2-CG2 3.74Å; L336-V346 HydrophobicContact CD2-CB 4.33Å; L336-V346 HydrophobicContact CD2-CG1 3.6Å; L336-V346 HydrophobicContact CD2-CG2 3.8Å; P340-V346 HydrophobicContact CB-CG1 4.15Å; L343-V346 HydrophobicContact CB-CB 3.99Å; L343-V346 HydrophobicContact CB-CG2 3.89Å; L343-V346 HydrophobicContact CD1-CG2 4.07Å; L343-V346 PolarHBondContact O-N 2.76Å; V346-R348 PolarHBondContact O-N 2.87Å; V346-L349 WeakPolarHBondContact O-CB 3.49Å; V346-L349 PolarHBondContact O-N 3.44Å; V346-L349 VanDerWaalsContact O-N 3.11Å; V346-I350 HydrophobicContact CG1-CD1 3.78Å; V346-I350 HydrophobicContact CG1-CG1 4.32Å; V346-I350 WeakPolarHBondContact O-CG1 3.27Å; V346-I350 PolarHBondContact O-N 2.86Å
347R77.6Confident72Confident60 Ų6082.8 Ų82.823%0.22641%0.405CS..Hα-helixtrans-52.7-52.6173.4-173.7-172-52.2173-1.2111.4E256 Y341 L343 L349 I350 D351E256-R347 IonicContact OE1-NH1 3.89Å; E256-R347 PolarHBondContact OE1-NH1 3.43Å; Y341-R347 HydrophobicContact CD1-CG 3.85Å; Y341-R347 HydrophobicContact CE1-CG 4.45Å; Y341-R347 PolarHBondContact O-NE 2.87Å; Y341-R347 PolarHBondContact O-NH2 3.27Å; L343-R347 PolarHBondContact O-N 2.84Å; R347-L349 VanDerWaalsContact C-N 3.27Å; R347-L349 PolarHBondContact O-N 3.44Å; R347-I350 PolarHBondContact O-N 3.48Å; R347-I350 VanDerWaalsContact O-N 3.09Å; R347-D351 WeakPolarHBondContact CG-OD2 3.25Å; R347-D351 PolarHBondContact O-N 3.2Å
348R67.4Low71.6Confident98 Ų9883.5 Ų83.537%0.3740%0.4SS..Hα-helixtrans-56.7-39.5176.9-76.2177.9175.4177.8-4113R344 V346 N352R344-R348 WeakPolarHBondContact O-CG 3.36Å; R344-R348 PolarHBondContact O-N 3Å; R344-R348 VanDerWaalsContact O-N 3.13Å; V346-R348 PolarHBondContact O-N 2.87Å; R348-N352 VanDerWaalsContact O-CB 3.25Å; R348-N352 WeakPolarHBondContact O-CB 3.4Å; R348-N352 PolarHBondContact O-N 3.35Å; R348-N352 PolarHBondContact O-ND2 3.49Å
349L75.4Confident70.5Confident115 Ų11573.2 Ų73.260%0.60237%0.366SS*.Hα-helixtrans-65.6-44.6175.9-98.8156.1000111.9P345 V346 R347 N352 C353P345-L349 PolarHBondContact O-N 3.2Å; V346-L349 WeakPolarHBondContact O-CB 3.49Å; V346-L349 PolarHBondContact O-N 3.44Å; V346-L349 VanDerWaalsContact O-N 3.11Å; R347-L349 VanDerWaalsContact C-N 3.27Å; R347-L349 PolarHBondContact O-N 3.44Å; L349-N352 PolarHBondContact O-N 3.47Å; L349-C353 WeakPolarHBondContact O-CB 3.36Å; L349-C353 PolarHBondContact O-N 3.01Å; L349-C353 PolarHBondContact O-SG 3.17Å
350I80.3Confident69.9Low50 Ų5076.5 Ų76.526%0.25638%0.378SS..Hα-helixtrans-63.1-48.9177.7-68.1168.9000110.3P340 Y341 V346 R347 N352 C353 A354P340-I350 HydrophobicContact CB-CD1 3.76Å; P340-I350 HydrophobicContact CG-CD1 4.36Å; Y341-I350 HydrophobicContact CE1-CG2 4.24Å; Y341-I350 WeakPolarHBondContact OH-CG2 3.32Å; V346-I350 HydrophobicContact CG1-CD1 3.78Å; V346-I350 HydrophobicContact CG1-CG1 4.32Å; V346-I350 WeakPolarHBondContact O-CG1 3.27Å; V346-I350 PolarHBondContact O-N 2.86Å; R347-I350 PolarHBondContact O-N 3.48Å; R347-I350 VanDerWaalsContact O-N 3.09Å; I350-N352 VanDerWaalsContact C-N 3.33Å; I350-N352 PolarHBondContact O-N 3.13Å; I350-C353 PolarHBondContact O-N 3.38Å; I350-A354 WeakPolarHBondContact O-CB 3.1Å; I350-A354 PolarHBondContact O-N 3.22Å
351D71.7Confident68.9Low20 Ų2083.7 Ų83.711%0.10740%0.401CS..Hα-helixtrans-61-42.7179.9-63-18.2000110.9V123 R347 C353 A354 F355 F374V123-D351 HydrophobicContact CG2-CB 4.07Å; R347-D351 WeakPolarHBondContact CG-OD2 3.25Å; R347-D351 PolarHBondContact O-N 3.2Å; D351-C353 PolarHBondContact O-N 3.46Å; D351-A354 PolarHBondContact O-N 3.19Å; D351-F355 WeakPolarHBondContact O-CB 3.43Å; D351-F355 PolarHBondContact O-N 3.16Å; D351-F374 HydrophobicContact CB-CE1 4.45Å
352N70.2Confident68.1Low40 Ų4080.4 Ų80.421%0.21439%0.39CS..Hα-helixtrans-63.4-41.4175.4-78.8-7.9000112.8E121 V123 R348 L349 I350 R356E121-N352 PolarHBondContact O-ND2 3.46Å; E121-N352 PolarHBondContact O-OD1 2.86Å; V123-N352 VanDerWaalsContact CG2-OD1 3.29Å; V123-N352 WeakPolarHBondContact CG2-OD1 3.38Å; R348-N352 VanDerWaalsContact O-CB 3.25Å; R348-N352 WeakPolarHBondContact O-CB 3.4Å; R348-N352 PolarHBondContact O-N 3.35Å; R348-N352 PolarHBondContact O-ND2 3.49Å; L349-N352 PolarHBondContact O-N 3.47Å; I350-N352 VanDerWaalsContact C-N 3.33Å; I350-N352 PolarHBondContact O-N 3.13Å; N352-R356 WeakPolarHBondContact O-CG 3.45Å; N352-R356 PolarHBondContact O-N 3.1Å
353C76.3Confident67.2Low58 Ų5884.8 Ų84.839%0.39240%0.398SS..Hα-helixtrans-68.5-42.7176.5-74.20000111.7L349 I350 D351 F355 R356 L357L349-C353 WeakPolarHBondContact O-CB 3.36Å; L349-C353 PolarHBondContact O-N 3.01Å; L349-C353 PolarHBondContact O-SG 3.17Å; I350-C353 PolarHBondContact O-N 3.38Å; D351-C353 PolarHBondContact O-N 3.46Å; C353-F355 VanDerWaalsContact C-N 3.31Å; C353-F355 PolarHBondContact O-N 3.09Å; C353-R356 PolarHBondContact O-N 3.04Å; C353-L357 WeakPolarHBondContact O-CG 3.14Å; C353-L357 PolarHBondContact O-N 3.46Å
354A73.7Confident66.3Low33 Ų3387.8 Ų87.827%0.27341%0.408SS..Hα-helixtrans-59.8-43.7176.400000110.4I350 D351 L357 Y358I350-A354 WeakPolarHBondContact O-CB 3.1Å; I350-A354 PolarHBondContact O-N 3.22Å; D351-A354 PolarHBondContact O-N 3.19Å; A354-L357 PolarHBondContact O-N 3.33Å; A354-Y358 HydrophobicContact CB-CD2 4.41Å; A354-Y358 WeakPolarHBondContact O-CB 3.37Å; A354-Y358 VanDerWaalsContact O-CD2 3.23Å; A354-Y358 WeakPolarHBondContact O-CD2 3.29Å; A354-Y358 PolarHBondContact O-N 3.01Å
355F63.5Low65.9Low46 Ų4685.9 Ų85.920%0.20242%0.419CS..Hα-helixtrans-68.1-39.8176-175-105.9000113.2T120 D351 C353 L357 G359 V362 L373T120-F355 HydrophobicContact CG2-CB 4.43Å; T120-F355 HydrophobicContact CG2-CD1 3.69Å; T120-F355 HydrophobicContact CG2-CD2 3.26Å; T120-F355 HydrophobicContact CG2-CE1 3.6Å; T120-F355 HydrophobicContact CG2-CE2 3.2Å; T120-F355 HydrophobicContact CG2-CG 3.51Å; T120-F355 HydrophobicContact CG2-CZ 3.36Å; D351-F355 WeakPolarHBondContact O-CB 3.43Å; D351-F355 PolarHBondContact O-N 3.16Å; C353-F355 VanDerWaalsContact C-N 3.31Å; C353-F355 PolarHBondContact O-N 3.09Å; F355-L357 PolarHBondContact O-N 2.63Å; F355-G359 WeakPolarHBondContact O-CA 3.41Å; F355-G359 PolarHBondContact O-N 2.75Å; F355-V362 HydrophobicContact CD2-CG2 4.45Å; F355-V362 HydrophobicContact CE2-CG2 4.26Å; F355-L373 HydrophobicContact CD2-CD1 4.24Å
356R70Confident64.8Low197 Ų19788.9 Ų88.974%0.74342%0.424SS*.Hα-helixtrans-61-35.5175-74.5-176.3-143.8174.23112.8N352 C353N352-R356 WeakPolarHBondContact O-CG 3.45Å; N352-R356 PolarHBondContact O-N 3.1Å; C353-R356 PolarHBondContact O-N 3.04Å
357L68.9Low63.1Low111 Ų11195.6 Ų95.658%0.58145%0.454SS*.Hα-helixtrans-81.1-44.2-179.7-74.5164.6000112.1C353 A354 F355 H360C353-L357 WeakPolarHBondContact O-CG 3.14Å; C353-L357 PolarHBondContact O-N 3.46Å; A354-L357 PolarHBondContact O-N 3.33Å; F355-L357 PolarHBondContact O-N 2.63Å; L357-H360 PolarHBondContact O-CE1 3.38Å; L357-H360 PolarHBondContact O-ND1 3.25Å
358Y67.6Low61.8Low144 Ų14496.5 Ų96.557%0.56546%0.461SS*.Hα-helixtrans-111.81.1-170-55.1-66.6000114A354 H360 W361A354-Y358 HydrophobicContact CB-CD2 4.41Å; A354-Y358 WeakPolarHBondContact O-CB 3.37Å; A354-Y358 VanDerWaalsContact O-CD2 3.23Å; A354-Y358 WeakPolarHBondContact O-CD2 3.29Å; A354-Y358 PolarHBondContact O-N 3.01Å; Y358-H360 PolarHBondContact O-N 3.34Å; Y358-H360 VanDerWaalsContact O-N 3.17Å; Y358-W361 WeakPolarHBondContact O-CA 3.44Å; Y358-W361 WeakPolarHBondContact O-CB 3.38Å; Y358-W361 PolarHBondContact O-N 3.19Å
359G57.2Low60.9Low16 Ų1693.8 Ų93.817%0.16545%0.454CS..G310 helixtrans-59.8-29.6-177.800000112.8F355 W361 V362F355-G359 WeakPolarHBondContact O-CA 3.41Å; F355-G359 PolarHBondContact O-N 2.75Å; G359-W361 PolarHBondContact O-N 2.98Å; G359-V362 WeakPolarHBondContact O-CB 3.18Å; G359-V362 PolarHBondContact O-N 3.19Å; G359-V362 VanDerWaalsContact O-N 3.09Å
360H60.3Low59.8Low150 Ų15088.8 Ų88.869%0.69443%0.427SS*.G310 helixtrans-68.2-14.1173.167.9-80.1000114.3L357 Y358L357-H360 PolarHBondContact O-CE1 3.38Å; L357-H360 PolarHBondContact O-ND1 3.25Å; Y358-H360 PolarHBondContact O-N 3.34Å; Y358-H360 VanDerWaalsContact O-N 3.17Å
361W51.1Low58.5Low188 Ų18887 Ų8771%0.71242%0.419SS*.G310 helixtrans-93.7-10.3173.2-67.162.3000112.6Y358 G359 K363Y358-W361 WeakPolarHBondContact O-CA 3.44Å; Y358-W361 WeakPolarHBondContact O-CB 3.38Å; Y358-W361 PolarHBondContact O-N 3.19Å; G359-W361 PolarHBondContact O-N 2.98Å; W361-K363 PolarHBondContact O-N 3.4Å
362V55.3Low57.7Low25 Ų2588.2 Ų88.215%0.15243%0.432CS..SBendtrans-77.8101.3171.7-174.60000106.1F355 G359 K364 L373F355-V362 HydrophobicContact CD2-CG2 4.45Å; F355-V362 HydrophobicContact CE2-CG2 4.26Å; G359-V362 WeakPolarHBondContact O-CB 3.18Å; G359-V362 PolarHBondContact O-N 3.19Å; G359-V362 VanDerWaalsContact O-N 3.09Å; V362-K364 PolarHBondContact O-N 3.18Å; V362-L373 HydrophobicContact CG2-CD1 3.81Å; V362-L373 HydrophobicContact CG2-CD2 3.56Å; V362-L373 HydrophobicContact CG2-CG 3.8Å
363K49.6Very low56.8Low152 Ų15289.3 Ų89.366%0.66144%0.438SS*.  trans-69.1124.9-178.6-64.2-174.9175.2-175.30108.9W361 Q368W361-K363 PolarHBondContact O-N 3.4Å; K363-Q368 VanDerWaalsContact N-OE1 3.16Å
364K51.3Low55.7Low131 Ų13190.2 Ų90.257%0.5744%0.436SS*.  trans-73.9117.6171.5-61.9-172.4165.5-149.10108.5E114 D117 V362E114-K364 IonicContact OE1-NZ 3.44Å; E114-K364 PolarHBondContact OE1-NZ 3.29Å; E114-K364 VanDerWaalsContact OE1-NZ 3.1Å; E114-K364 IonicContact OE2-NZ 2.68Å; D117-K364 IonicContact OD1-NZ 2.69Å; D117-K364 IonicContact OD2-NZ 3.59Å; D117-K364 PolarHBondContact OD2-NZ 2.95Å; V362-K364 PolarHBondContact O-N 3.18Å
365G53.6Low54.8Low55 Ų5592.4 Ų92.457%0.56744%0.44SS*.SBendtrans145.8-175.717400000116.5Q367 Q368G365-Q367 PolarHBondContact O-N 3.23Å; G365-Q368 PolarHBondContact O-N 2.96Å
366E42.5Very low53.6Low156 Ų15698.1 Ų98.173%0.72947%0.467SS*.THydrogen-bonded Turntrans-53.1-21.4-170.9-69.3178156.400115.8
367Q40.6Very low52.1Low162 Ų16295.9 Ų95.976%0.75747%0.465SS*.THydrogen-bonded Turntrans-100-4-175.6-69.6-161.6-7.900116G365G365-Q367 PolarHBondContact O-N 3.23Å
368Q50.3Low50.5Low80 Ų8095.7 Ų95.737%0.37447%0.471SS..  trans-141.4113.3-175.1-71.9-170.1-8.200115.6K363 G365K363-Q368 VanDerWaalsContact N-OE1 3.16Å; G365-Q368 PolarHBondContact O-N 2.96Å
369N50.5Low49.2Very low41 Ų4193.1 Ų93.122%0.21947%0.472CS..  trans-93.4143.3173.8-158.3-24.5000110.3A371 A372N369-A371 PolarHBondContact O-N 3.38Å; N369-A372 PolarHBondContact O-N 2.86Å
370R50.9Low48.2Very low9 Ų9103 Ų1033%0.03450%0.504CS..G310 helixtrans-45.5-31.4-176.3-173.3-159.617883.5-0.5114.8F116 L119 T120 V123 G229 A372 L373 F374F116-R370 HydrophobicContact CE2-CB 4.38Å; F116-R370 HydrophobicContact CZ-CB 4.41Å; L119-R370 PolarHBondContact O-NH2 3.27Å; T120-R370 VanDerWaalsContact CB-NH1 3.34Å; T120-R370 PolarHBondContact OG1-NH1 3.14Å; V123-R370 PolarHBondContact O-NH2 3.36Å; G229-R370 WeakPolarHBondContact O-CD 3.3Å; G229-R370 PolarHBondContact O-NE 3.48Å; R370-A372 PolarHBondContact O-N 2.94Å; R370-L373 HydrophobicContact CG-CD1 4.41Å; R370-L373 WeakPolarHBondContact O-CB 3.35Å; R370-L373 PolarHBondContact O-N 3.3Å; R370-F374 HydrophobicContact CG-CE2 4.08Å
371A53.4Low47Very low12 Ų12101.2 Ų101.210%0.09951%0.508CS..G310 helixtrans-59-16.6178.500000114.4W234 N369 L373 F374W234-A371 HydrophobicContact CB-CB 4.45Å; W234-A371 HydrophobicContact CD2-CB 3.4Å; W234-A371 HydrophobicContact CE3-CB 4.05Å; W234-A371 HydrophobicContact CG-CB 3.56Å; W234-A371 HydrophobicContact CH2-CB 4.46Å; W234-A371 HydrophobicContact CZ2-CB 3.9Å; N369-A371 PolarHBondContact O-N 3.38Å; A371-L373 VanDerWaalsContact C-N 3.26Å; A371-L373 PolarHBondContact O-N 2.81Å; A371-F374 PolarHBondContact O-N 3.23Å
372A54.8Low46.2Very low46 Ų46101.2 Ų101.238%0.3851%0.513SS..G310 helixtrans-60.6-31.3169.600000113.6N369 R370 F374N369-A372 PolarHBondContact O-N 2.86Å; R370-A372 PolarHBondContact O-N 2.94Å; A372-F374 PolarHBondContact O-N 3.12Å
373L51.3Low45.1Very low64 Ų64105.8 Ų105.834%0.33554%0.544SS..G310 helixtrans-67.4-23.6177.5-77.9163.4000113.6F355 V362 R370 A371F355-L373 HydrophobicContact CD2-CD1 4.24Å; V362-L373 HydrophobicContact CG2-CD1 3.81Å; V362-L373 HydrophobicContact CG2-CD2 3.56Å; V362-L373 HydrophobicContact CG2-CG 3.8Å; R370-L373 HydrophobicContact CG-CD1 4.41Å; R370-L373 WeakPolarHBondContact O-CB 3.35Å; R370-L373 PolarHBondContact O-N 3.3Å; A371-L373 VanDerWaalsContact C-N 3.26Å; A371-L373 PolarHBondContact O-N 2.81Å
374F53.2Low44.3Very low77 Ų77106.3 Ų106.334%0.33855%0.552SS.*G310 helixtrans-103.516.3-173.5-57.1-74.5000112.6D351 R370 A371 A372 H376D351-F374 HydrophobicContact CB-CE1 4.45Å; R370-F374 HydrophobicContact CG-CE2 4.08Å; A371-F374 PolarHBondContact O-N 3.23Å; A372-F374 PolarHBondContact O-N 3.12Å; F374-H376 PolarHBondContact O-N 2.87Å
375Q54Low43.5Very low79 Ų79107.9 Ų107.937%0.36956%0.563SS.*  trans-73.2122.5175.8-67.8-17812.300110.5W234 Q377W234-Q375 HydrophobicContact CH2-CG 4.26Å; Q375-Q377 VanDerWaalsContact C-N 3.29Å; Q375-Q377 PolarHBondContact O-N 3.01Å
376H40.2Very low42.2Very low165 Ų165109.7 Ų109.776%0.76457%0.573SS**SBendtrans-85.23.7178-68.8-66.8000114.2F374F374-H376 PolarHBondContact O-N 2.87Å
377Q37.5Very low41.9Very low150 Ų150107.9 Ų107.970%0.70157%0.573SS**SBendtrans-129.3132.2176.2-70.4-176-1.100109.5Q375Q375-Q377 VanDerWaalsContact C-N 3.29Å; Q375-Q377 PolarHBondContact O-N 3.01Å
378P35.8Very low41.3Very low108 Ų108108.5 Ų108.570%0.70158%0.576SS**PPolyproline II helixtrans-60.8149.3173.725.4-31.8000109.7R380P378-R380 PolarHBondContact O-N 2.83Å; P378-R380 VanDerWaalsContact O-N 3.1Å
379P40.9Very low40.2Very low90 Ų90113.4 Ų113.458%0.58460%0.598SS**PPolyproline II helixtrans-53.4124.2166.422.2-29.8000107.4S381P379-S381 PolarHBondContact O-N 3.32Å; P379-S381 VanDerWaalsContact O-N 3.08Å
380R35.2Very low39.7Very low224 Ų224121.3 Ų121.385%0.84563%0.634SS**PPolyproline II helixtrans-52123.8172.7-72.8-175.4179.1176.6-0.5106.8P378 F382P378-R380 PolarHBondContact O-N 2.83Å; P378-R380 VanDerWaalsContact O-N 3.1Å; R380-F382 PolarHBondContact O-N 3.45Å
381S34.1Very low38.5Very low111 Ų111124.3 Ų124.378%0.77667%0.668SS**  trans-45130.8-176.7450000110.9P379P379-S381 PolarHBondContact O-N 3.32Å; P379-S381 VanDerWaalsContact O-N 3.08Å
382F34.9Very low37.4Very low188 Ų188131.1 Ų131.183%0.82570%0.703SS**  trans-45.1133.4169.9-74-89.3000110.5R380 I384R380-F382 PolarHBondContact O-N 3.45Å; F382-I384 PolarHBondContact O-N 3.09Å
383P33Very low36.3Very low122 Ų122132.8 Ų132.879%0.79271%0.711SS**  trans-59.5129.5158.2-11.926.6000107.9M385P383-M385 PolarHBondContact O-N 3.22Å
384I32.3Very low35.4Very low163 Ų163136.9 Ų136.984%0.83673%0.734SS**  trans-58.9126.6176.5-67.7164.9000109F382F382-I384 PolarHBondContact O-N 3.09Å
385M33.8Very low34.5Very low163 Ų163138.1 Ų138.180%0.80375%0.747SS**  trans15.7104.1161.5-64.9179.574.700116.9P383P383-M385 PolarHBondContact O-N 3.22Å
386A26.6Very low33.9Very low93 Ų93139.6 Ų139.677%0.76976%0.757SS**  trans-10612413600000106.6E388A386-E388 PolarHBondContact O-N 2.7Å
387T37.2Very low33.9Very low118 Ų118135.6 Ų135.672%0.72474%0.744SS**  trans-59121170.342.20000109.6
388E28.3Very low34.2Very low176 Ų176137.4 Ų137.482%0.82275%0.752SS**  trans-162110.4159.6-107.8155.9-145.100109.4A386A386-E388 PolarHBondContact O-N 2.7Å
389E26.3Very low34.4Very low182 Ų182138.5 Ų138.585%0.8575%0.753SS**  trans45.9126.7142.2-60.1-175.616500121.1G391E389-G391 PolarHBondContact O-N 3.24Å
390E39.6Very low34.5Very low208 Ų208140.4 Ų140.497%0.97275%0.754SS**  trans-49.9121.7160.9-69.9175141.700110.2
391G26.9Very low34.8Very low71 Ų71131 Ų13173%0.73272%0.724SS**  trans-155.998.2178.300000110.7E389E389-G391 PolarHBondContact O-N 3.24Å
392D29.3Very low35.1Very low156 Ų156129.3 Ų129.383%0.83472%0.716SS**  trans36.5143.3155.2-87.1-27.9000124.4
393S31.9Very low35.5Very low81 Ų81126 Ų12657%0.56671%0.707SS**  trans-29.4129.2162.347.90000115.6T395S393-T395 PolarHBondContact O-N 3.29Å; S393-T395 PolarHBondContact O-OG1 3.11Å
394N31.9Very low36Very low150 Ų150121 Ų12180%0.80267%0.674SS**  trans-68.272.6159.5-86.4-0.9000110.1
395T35.5Very low36.2Very low102 Ų102121 Ų12163%0.62668%0.675SS**  trans-78.2134.914820.40000107.5S393 T397S393-T395 PolarHBondContact O-N 3.29Å; S393-T395 PolarHBondContact O-OG1 3.11Å; T395-T397 PolarHBondContact O-N 3.18Å
396I39.9Very low36.2Very low110 Ų110120 Ų12056%0.56469%0.693SS**  trans-57.9110172.3-61.3170.4000106.9L187L187-I396 HydrophobicContact CD2-CD1 3.6Å; L187-I396 HydrophobicContact CG-CD1 4.46Å
397T41.5Very low36.7Very low82 Ų82121.4 Ų121.450%0.50369%0.689SS.*  trans-82.1142.8169.452.80000108.6T395 D399 E400T395-T397 PolarHBondContact O-N 3.18Å; T397-D399 PolarHBondContact O-N 3.48Å; T397-E400 PolarHBondContact O-N 2.82Å; T397-E400 VanDerWaalsContact O-N 3.08Å
398E43.1Very low36.7Very low187 Ų187121.6 Ų121.687%0.87469%0.688SS**Hα-helixtrans-50.9-22.1-179.7-68175.8155.300113.2
399D40.5Very low37.1Very low132 Ų132118.6 Ų118.671%0.70668%0.68SS**Hα-helixtrans-71.4-28.1178.9-85.9-23000115.1T397 A401T397-D399 PolarHBondContact O-N 3.48Å; D399-A401 VanDerWaalsContact C-N 3.3Å; D399-A401 PolarHBondContact O-N 3.17Å
400E42.4Very low37.8Very low129 Ų129114.8 Ų114.860%0.60367%0.67SS**Hα-helixtrans-74.2-22.8178.1-76-158.614900112.7T397 L403T397-E400 PolarHBondContact O-N 2.82Å; T397-E400 VanDerWaalsContact O-N 3.08Å; E400-L403 PolarHBondContact O-N 3.48Å
401A41Very low37.6Very low28 Ų28109 Ų10923%0.23165%0.651CS.*Hα-helixtrans-69.3-33.2176.700000112.3M203 D399 L403 V404M203-A401 HydrophobicContact CG-CB 4.28Å; D399-A401 VanDerWaalsContact C-N 3.3Å; D399-A401 PolarHBondContact O-N 3.17Å; A401-L403 PolarHBondContact O-N 2.64Å; A401-V404 WeakPolarHBondContact O-CG2 3.49Å; A401-V404 PolarHBondContact O-N 3.34Å
402A41.7Very low38.4Very low74 Ų74111.5 Ų111.561%0.61265%0.646SS**Hα-helixtrans-66.2-23.9179.800000113.3V404A402-V404 VanDerWaalsContact C-N 3.28Å; A402-V404 PolarHBondContact O-N 3.24Å
403L42.3Very low39Very low118 Ų118108.4 Ų108.462%0.61863%0.632SS**G310 helixtrans-78-7.9-176.5-128.7104.9000114.3E400 A401 L405E400-L403 PolarHBondContact O-N 3.48Å; A401-L403 PolarHBondContact O-N 2.64Å; L403-L405 VanDerWaalsContact C-N 3.25Å; L403-L405 PolarHBondContact O-N 2.86Å
404V44.9Very low39.5Very low19 Ų19110.5 Ų110.512%0.11564%0.637CS.*G310 helixtrans-71.3-20.2-177.9-177.80000112.4M203 I239 M246 A401 A402M203-V404 HydrophobicContact CE-CG1 4.46Å; M203-V404 HydrophobicContact CE-CG2 3.82Å; M203-V404 HydrophobicContact SD-CB 4.39Å; M203-V404 HydrophobicContact SD-CG1 4.35Å; M203-V404 HydrophobicContact SD-CG2 4.29Å; I239-V404 HydrophobicContact CD1-CB 4.5Å; I239-V404 HydrophobicContact CD1-CG2 3.3Å; I239-V404 HydrophobicContact CG1-CG2 4.05Å; M246-V404 HydrophobicContact SD-CG1 4.06Å; A401-V404 WeakPolarHBondContact O-CG2 3.49Å; A401-V404 PolarHBondContact O-N 3.34Å; A402-V404 VanDerWaalsContact C-N 3.28Å; A402-V404 PolarHBondContact O-N 3.24Å
405L35.4Very low40.2Very low161 Ų161107.2 Ų107.284%0.84362%0.624SS**G310 helixtrans-100.95.3-171.2-68.6173.5000115.5L403L403-L405 VanDerWaalsContact C-N 3.25Å; L403-L405 PolarHBondContact O-N 2.86Å
406A34.2Very low40.6Very low144 Ų144107.6 Ų107.6100%1.1962%0.624SS**  trans-89.90177.900000113.8

Retrieved 406 of 406 residues in 79.2 ms (Link to these results)