A0A061IDN7_CRIGR Loading...

R-spondin-3

Activator of the canonical Wnt signaling pathway by acting as a ligand for LGR4-6 receptors, which acts as a key regulator of angiogenesis. Upon binding to LGR4-6 (LGR4, LGR5 or LGR6), LGR4-6 associate with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. Also regulates the canonical Wnt/beta-catenin-dependent pathway and non-canonical Wnt signaling by acting as an inhibitor of ZNRF3, an important regulator of the Wnt signaling pathway. Acts as a ligand for frizzled FZD8 and LRP6. May negatively regulate the TGF-beta pathway. Acts as a key regulator of angiogenesis by controlling vascular stability and pruning: acts by activating the non-canonical Wnt signaling pathway in endothelial cells. Can also amplify Wnt signaling pathway independently of LGR4-6 receptors, possibly by acting as a direct antagonistic ligand to RNF43 and ZNRF3.

AlphaFold DB , UniProt , Accession A0A061IDN7, Species CRIGR (Cricetulus griseus, Chinese hamster), Gene Rspo3, Length 275 aa.

Structure Viewer

Loading PAE data...

(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	59.5	Low	61.3	Low	233 Å²	233	143.1 Å²	143.1	100%	1.148	67%	0.669	S	S	*	*				0	58.9	0	-61.7	-152.7	-173.1	0	0	111.6
2	H	59	Low	61.7	Low	149 Å²	149	139.1 Å²	139.1	69%	0.69	65%	0.654	S	S	*	*			trans	-131.4	-6.6	-177	-121.4	-84.7	0	0	0	114.4
3	L	57.5	Low	61.5	Low	151 Å²	151	135.3 Å²	135.3	79%	0.791	64%	0.64	S	S	*	*	H	α-helix	trans	-91	-14.6	180	-81.6	146.2	0	0	0	114.2
4	R	57.1	Low	61.2	Low	226 Å²	226	133.5 Å²	133.5	85%	0.853	64%	0.636	S	S	*	*	H	α-helix	trans	-84.7	-22.1	176.8	-66.7	-134.8	170.1	177.7	-2.2	113.8	W8	R4-W8 PolarHBondContact O-N 2.95Å
5	L	59	Low	60.9	Low	117 Å²	117	133.4 Å²	133.4	61%	0.613	63%	0.632	S	S	*	*	H	α-helix	trans	-76.1	-33.9	176.6	-73.5	165.4	0	0	0	112.2	W8 F9	L5-W8 PolarHBondContact O-N 3.32Å; L5-F9 PolarHBondContact O-N 3.44Å
6	I	62.1	Low	60.6	Low	92 Å²	92	133.5 Å²	133.5	47%	0.472	63%	0.634	S	S	.	*	H	α-helix	trans	-69.4	-39.7	178.5	-60.4	167.5	0	0	0	110.5	W8 F9 F10	I6-W8 VanDerWaalsContact C-N 3.34Å; I6-W8 PolarHBondContact O-N 3.01Å; I6-F9 PolarHBondContact O-N 3.36Å; I6-F10 HydrophobicContact CG2-CD2 3.93Å; I6-F10 HydrophobicContact CG2-CE2 3.71Å; I6-F10 VanDerWaalsContact O-CD2 3.27Å; I6-F10 WeakPolarHBondContact O-CD2 3.36Å; I6-F10 PolarHBondContact O-N 3.05Å
7	S	64.3	Low	60.1	Low	67 Å²	67	134.9 Å²	134.9	47%	0.469	64%	0.641	S	S	.	*	H	α-helix	trans	-64.4	-36.3	175.4	-178.1	0	0	0	0	112.8	I11	S7-I11 VanDerWaalsContact O-CD1 3.29Å; S7-I11 WeakPolarHBondContact O-CD1 3.42Å; S7-I11 VanDerWaalsContact O-CG1 3.23Å; S7-I11 WeakPolarHBondContact O-CG1 3.47Å; S7-I11 PolarHBondContact O-N 3.12Å
8	W	61.9	Low	59.7	Low	184 Å²	184	136.4 Å²	136.4	70%	0.697	64%	0.64	S	S	*	*	H	α-helix	trans	-72.6	-33.2	174.9	-86.4	24.5	0	0	0	112.7	R4 L5 I6 I11 I12	R4-W8 PolarHBondContact O-N 2.95Å; L5-W8 PolarHBondContact O-N 3.32Å; I6-W8 VanDerWaalsContact C-N 3.34Å; I6-W8 PolarHBondContact O-N 3.01Å; W8-I11 PolarHBondContact O-N 3.17Å; W8-I12 VanDerWaalsContact O-CG1 3.25Å; W8-I12 WeakPolarHBondContact O-CG1 3.46Å; W8-I12 PolarHBondContact O-N 3.45Å
9	F	66.8	Low	59.4	Low	130 Å²	130	133.6 Å²	133.6	57%	0.57	63%	0.629	S	S	*	*	H	α-helix	trans	-65.4	-41.1	177.5	-158.7	-102.1	0	0	0	112.5	L5 I6 I11 I12 L13	L5-F9 PolarHBondContact O-N 3.44Å; I6-F9 PolarHBondContact O-N 3.36Å; F9-I11 PolarHBondContact O-N 3.22Å; F9-I12 PolarHBondContact O-N 3.27Å; F9-L13 HydrophobicContact CD1-CD1 3.74Å; F9-L13 HydrophobicContact CD1-CG 4.36Å; F9-L13 HydrophobicContact CE1-CD1 3.63Å; F9-L13 HydrophobicContact CE1-CG 4.27Å; F9-L13 WeakPolarHBondContact O-CG 3.35Å; F9-L13 PolarHBondContact O-N 3.03Å
10	F	61.6	Low	58.9	Low	127 Å²	127	130.3 Å²	130.3	56%	0.557	63%	0.632	S	S	*	*	H	α-helix	trans	-68.7	-31	175	-79.3	-72.3	0	0	0	113.7	I6 N14	I6-F10 HydrophobicContact CG2-CD2 3.93Å; I6-F10 HydrophobicContact CG2-CE2 3.71Å; I6-F10 VanDerWaalsContact O-CD2 3.27Å; I6-F10 WeakPolarHBondContact O-CD2 3.36Å; I6-F10 PolarHBondContact O-N 3.05Å; F10-N14 PolarHBondContact O-N 3.15Å; F10-N14 PolarHBondContact O-ND2 3.03Å
11	I	66.1	Low	58.5	Low	98 Å²	98	129 Å²	129	50%	0.503	64%	0.636	S	S	.	*	H	α-helix	trans	-70.8	-40.6	174.5	-66.8	165.6	0	0	0	110.3	S7 W8 F9 N14 F15	S7-I11 VanDerWaalsContact O-CD1 3.29Å; S7-I11 WeakPolarHBondContact O-CD1 3.42Å; S7-I11 VanDerWaalsContact O-CG1 3.23Å; S7-I11 WeakPolarHBondContact O-CG1 3.47Å; S7-I11 PolarHBondContact O-N 3.12Å; W8-I11 PolarHBondContact O-N 3.17Å; F9-I11 PolarHBondContact O-N 3.22Å; I11-N14 PolarHBondContact O-N 3.2Å; I11-F15 WeakPolarHBondContact O-CB 3.5Å; I11-F15 PolarHBondContact O-N 3.21Å
12	I	65.3	Low	58.1	Low	95 Å²	95	124.4 Å²	124.4	49%	0.487	61%	0.612	S	S	.	*	H	α-helix	trans	-68.9	-38.5	178.1	-66.9	165.7	0	0	0	111.7	W8 F9 F15 M16	W8-I12 VanDerWaalsContact O-CG1 3.25Å; W8-I12 WeakPolarHBondContact O-CG1 3.46Å; W8-I12 PolarHBondContact O-N 3.45Å; F9-I12 PolarHBondContact O-N 3.27Å; I12-F15 PolarHBondContact O-N 3.22Å; I12-M16 PolarHBondContact O-N 3.21Å
13	L	60	Low	57.6	Low	90 Å²	90	124.2 Å²	124.2	47%	0.471	62%	0.616	S	S	.	*	H	α-helix	trans	-65.7	-40.6	175.7	-73	173.3	0	0	0	112.4	F9 F15 M16 E17	F9-L13 HydrophobicContact CD1-CD1 3.74Å; F9-L13 HydrophobicContact CD1-CG 4.36Å; F9-L13 HydrophobicContact CE1-CD1 3.63Å; F9-L13 HydrophobicContact CE1-CG 4.27Å; F9-L13 WeakPolarHBondContact O-CG 3.35Å; F9-L13 PolarHBondContact O-N 3.03Å; L13-F15 VanDerWaalsContact C-N 3.31Å; L13-F15 PolarHBondContact O-N 3.28Å; L13-M16 PolarHBondContact O-N 3.38Å; L13-E17 PolarHBondContact O-N 3.26Å
14	N	57.1	Low	57.2	Low	110 Å²	110	122 Å²	122	59%	0.588	62%	0.619	S	S	*	*	H	α-helix	trans	-67.5	-29.5	173.2	-86.4	-92.2	0	0	0	112.7	F10 I11 Y18	F10-N14 PolarHBondContact O-N 3.15Å; F10-N14 PolarHBondContact O-ND2 3.03Å; I11-N14 PolarHBondContact O-N 3.2Å; N14-Y18 PolarHBondContact O-N 3.09Å
15	F	56.8	Low	56.9	Low	132 Å²	132	116 Å²	116	58%	0.579	61%	0.612	S	S	*	*	H	α-helix	trans	-74.9	-35.3	178.4	-138.2	-101.5	0	0	0	112.7	I11 I12 L13 I19	I11-F15 WeakPolarHBondContact O-CB 3.5Å; I11-F15 PolarHBondContact O-N 3.21Å; I12-F15 PolarHBondContact O-N 3.22Å; L13-F15 VanDerWaalsContact C-N 3.31Å; L13-F15 PolarHBondContact O-N 3.28Å; F15-I19 HydrophobicContact CD1-CD1 3.59Å; F15-I19 HydrophobicContact CD1-CG1 4.4Å; F15-I19 HydrophobicContact CE1-CD1 3.81Å; F15-I19 WeakPolarHBondContact O-CG1 3.47Å; F15-I19 PolarHBondContact O-N 2.89Å
16	M	55.9	Low	56.5	Low	135 Å²	135	122.8 Å²	122.8	67%	0.665	63%	0.629	S	S	*	*	H	α-helix	trans	-74.6	-28.1	177.2	-72.5	-62.1	-148.8	0	0	113.3	I12 L13 G20	I12-M16 PolarHBondContact O-N 3.21Å; L13-M16 PolarHBondContact O-N 3.38Å; M16-G20 PolarHBondContact O-N 3.06Å
17	E	52	Low	56	Low	158 Å²	158	122.2 Å²	122.2	74%	0.738	65%	0.646	S	S	*	*	H	α-helix	trans	-76.4	-30.6	174.2	-153.2	165.3	-162.5	0	0	111.9	L13	L13-E17 PolarHBondContact O-N 3.26Å
18	Y	52.7	Low	55.1	Low	162 Å²	162	130.8 Å²	130.8	64%	0.635	67%	0.668	S	S	*	*	H	α-helix	trans	-73.2	-35.7	174.4	-169.2	-104.1	0	0	0	113.5	N14 G20	N14-Y18 PolarHBondContact O-N 3.09Å; Y18-G20 VanDerWaalsContact C-N 3.34Å
19	I	53.2	Low	54.2	Low	83 Å²	83	133.7 Å²	133.7	43%	0.426	68%	0.679	S	S	.	*	H	α-helix	trans	-76.3	-22.5	178.3	-64	171.3	0	0	0	111.9	F15 S21	F15-I19 HydrophobicContact CD1-CD1 3.59Å; F15-I19 HydrophobicContact CD1-CG1 4.4Å; F15-I19 HydrophobicContact CE1-CD1 3.81Å; F15-I19 WeakPolarHBondContact O-CG1 3.47Å; F15-I19 PolarHBondContact O-N 2.89Å; I19-S21 VanDerWaalsContact C-N 3.29Å; I19-S21 PolarHBondContact O-N 2.9Å
20	G	50.2	Low	52.9	Low	66 Å²	66	136.6 Å²	136.6	68%	0.68	69%	0.694	S	S	*	*	T	Hydrogen-bonded Turn	trans	-69.3	-18.7	174.4	0	0	0	0	0	115.1	M16 Y18	M16-G20 PolarHBondContact O-N 3.06Å; Y18-G20 VanDerWaalsContact C-N 3.34Å
21	S	51.3	Low	52.2	Low	103 Å²	103	141.5 Å²	141.5	72%	0.72	71%	0.709	S	S	*	*	T	Hydrogen-bonded Turn	trans	-91.9	-2.3	-177.3	-168.7	0	0	0	0	114.8	I19	I19-S21 VanDerWaalsContact C-N 3.29Å; I19-S21 PolarHBondContact O-N 2.9Å
22	Q	50.4	Low	50.9	Low	138 Å²	138	148.5 Å²	148.5	65%	0.645	73%	0.729	S	S	*	*	S	Bend	trans	-112.1	-2.1	-177.1	-69.8	-145.7	58	0	0	116.1
23	N	47.5	Very low	49.9	Very low	145 Å²	145	152 Å²	152	78%	0.775	75%	0.746	S	S	*	*			trans	-116.7	49.4	-176.8	-76.7	-33.4	0	0	0	114.7
24	A	50.3	Low	49.2	Very low	104 Å²	104	154.5 Å²	154.5	86%	0.86	76%	0.755	S	S	*	*			trans	-129.6	55.5	162.6	0	0	0	0	0	111.4
25	S	50.9	Low	49	Very low	99 Å²	99	155.6 Å²	155.6	69%	0.692	77%	0.767	S	S	*	*			trans	-154.4	94.3	164.1	51	0	0	0	0	112.1
26	R	50.3	Low	48.5	Very low	261 Å²	261	154.8 Å²	154.8	99%	0.985	77%	0.769	S	S	*	*			trans	-173.1	99.8	148.9	-102.9	155	-167.9	179.8	5.5	110
27	G	51.4	Low	48	Very low	80 Å²	80	153.4 Å²	153.4	83%	0.825	77%	0.768	S	S	*	*	S	Bend	trans	169.4	28.7	176.4	0	0	0	0	0	117.1
28	R	44.8	Very low	48.1	Very low	246 Å²	246	150.1 Å²	150.1	93%	0.928	76%	0.763	S	S	*	*	S	Bend	trans	-154.6	126.6	159.7	-115.6	171.3	-169.2	179.9	3.1	110.2	Q30	R28-Q30 PolarHBondContact O-N 2.77Å; R28-Q30 VanDerWaalsContact O-N 3.15Å
29	R	43.6	Very low	48.6	Very low	246 Å²	246	150.7 Å²	150.7	93%	0.928	77%	0.771	S	S	*	*			trans	-37.6	115.4	-179.9	-71.7	173	-179.3	166.7	-0.7	111.1	R31	R29-R31 VanDerWaalsContact C-N 3.31Å; R29-R31 PolarHBondContact O-N 3.43Å
30	Q	39.7	Very low	49.4	Very low	191 Å²	191	149.3 Å²	149.3	89%	0.893	78%	0.778	S	S	*	*			trans	-60.3	96.4	160.8	-79.1	175.9	-36.7	0	0	107.9	R28 R32	R28-Q30 PolarHBondContact O-N 2.77Å; R28-Q30 VanDerWaalsContact O-N 3.15Å; Q30-R32 PolarHBondContact O-N 3.13Å
31	R	45.7	Very low	50.9	Low	229 Å²	229	147.7 Å²	147.7	86%	0.864	76%	0.756	S	S	*	*			trans	-70.3	115	144.1	-79.9	-173.1	178	-178.8	-0	104.5	R29 M33	R29-R31 VanDerWaalsContact C-N 3.31Å; R29-R31 PolarHBondContact O-N 3.43Å; R31-M33 PolarHBondContact O-N 3.07Å
32	R	40.5	Very low	52.3	Low	246 Å²	246	150.5 Å²	150.5	93%	0.928	76%	0.757	S	S	*	*			trans	-48.4	106.1	164.7	-72	179.5	-168.5	165.4	2.9	106.9	Q30 H34	Q30-R32 PolarHBondContact O-N 3.13Å; R32-H34 PolarHBondContact O-N 3.34Å
33	M	42.9	Very low	53.7	Low	169 Å²	169	147 Å²	147	83%	0.833	76%	0.759	S	S	*	*			trans	-76.1	109.9	163.7	-79.6	-164.5	168.7	0	0	105.8	R31	R31-M33 PolarHBondContact O-N 3.07Å
34	H	47	Very low	55.6	Low	142 Å²	142	141.1 Å²	141.1	66%	0.657	73%	0.732	S	S	*	*			trans	-51.2	143	165.4	-166.8	-108.2	0	0	0	108.9	R32 N36	R32-H34 PolarHBondContact O-N 3.34Å; H34-N36 PolarHBondContact O-N 3.35Å
35	P	50.9	Low	57.7	Low	132 Å²	132	136.5 Å²	136.5	86%	0.857	69%	0.693	S	S	*	*	S	Bend	trans	-70.9	19.4	-176.9	-0.1	13.4	0	0	0	114.2
36	N	47.7	Very low	59.6	Low	115 Å²	115	134.2 Å²	134.2	62%	0.615	68%	0.681	S	S	*	*			trans	-145.8	70.1	-178.6	-153.9	5.3	0	0	0	109	H34 S38	H34-N36 PolarHBondContact O-N 3.35Å; N36-S38 VanDerWaalsContact C-N 3.34Å; N36-S38 PolarHBondContact O-N 3.07Å
37	V	45.9	Very low	61.6	Low	107 Å²	107	125.2 Å²	125.2	65%	0.648	65%	0.654	S	S	*	*			trans	-83.7	94.3	155.9	-179.2	0	0	0	0	104.1	Q39	V37-Q39 PolarHBondContact O-N 3.34Å
38	S	54.1	Low	63.6	Low	89 Å²	89	124.1 Å²	124.1	62%	0.622	63%	0.634	S	S	*	*			trans	-47.7	113.9	171.9	-19.3	0	0	0	0	107	N36 G40	N36-S38 VanDerWaalsContact C-N 3.34Å; N36-S38 PolarHBondContact O-N 3.07Å; S38-G40 PolarHBondContact O-N 3.23Å
39	Q	62.4	Low	65.8	Low	173 Å²	173	114 Å²	114	81%	0.808	60%	0.601	S	S	*	*			trans	-58.9	99.8	169.4	-165.9	152.9	-10.9	0	0	104.9	V37	V37-Q39 PolarHBondContact O-N 3.34Å
40	G	70.9	Confident	67.9	Low	55 Å²	55	110.2 Å²	110.2	57%	0.567	60%	0.599	S	S	*	*	P	Polyproline II helix	trans	-54.2	149.6	-168.1	0	0	0	0	0	110.5	S38 Q42	S38-G40 PolarHBondContact O-N 3.23Å; G40-Q42 PolarHBondContact O-N 3.19Å; G40-Q42 VanDerWaalsContact O-N 3.1Å
41	C	81	Confident	70.1	Confident	32 Å²	32	110.3 Å²	110.3	22%	0.216	59%	0.592	C	S	.	*	P	Polyproline II helix	trans	-53.9	121.2	-177.8	-55.3	0	0	0	0	111	C45 C48	C41-C45 HydrophobicContact CB-CB 3.69Å; C41-C48 WeakPolarHBondContact CA-SG 3.06Å; C41-C48 HydrophobicContact CB-CB 3.67Å; C41-C48 WeakPolarHBondContact CB-SG 3.45Å; C41-C48 WeakPolarHBondContact SG-CB 3.36Å; C41-C48 PolarHBondContact SG-N 3.18Å; C41-C48 CovalentContact SG-SG 2.03Å; C41-C48 PolarHBondContact SG-SG 3.35Å
42	Q	80.3	Confident	72.3	Confident	161 Å²	161	103.9 Å²	103.9	75%	0.752	58%	0.575	S	S	*	*	S	Bend	trans	-73.8	159.4	178.3	-72.5	178.6	-36.3	0	0	110.8	G40	G40-Q42 PolarHBondContact O-N 3.19Å; G40-Q42 VanDerWaalsContact O-N 3.1Å
43	G	79	Confident	74.7	Confident	66 Å²	66	93.2 Å²	93.2	68%	0.68	54%	0.542	S	S	*	.	T	Hydrogen-bonded Turn	trans	67.7	50.3	167.6	0	0	0	0	0	115.6	C45	G43-C45 PolarHBondContact O-N 3.45Å
44	G	88.8	Confident	77.1	Confident	20 Å²	20	85.7 Å²	85.7	21%	0.206	51%	0.505	C	S	.	.	T	Hydrogen-bonded Turn	trans	70.6	6.1	172.2	0	0	0	0	0	115.3	K58 L61	G44-K58 VanDerWaalsContact O-CB 3.24Å; G44-K58 WeakPolarHBondContact O-CB 3.36Å; G44-K58 WeakPolarHBondContact O-CG 3.45Å; G44-K58 PolarHBondContact O-N 3.2Å; G44-L61 VanDerWaalsContact O-CD1 3.29Å; G44-L61 WeakPolarHBondContact O-CD1 3.44Å
45	C	93.4	Very high	79.3	Confident	7 Å²	7	83.1 Å²	83.1	5%	0.047	50%	0.496	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-80.3	141	176.8	-173.3	0	0	0	0	111.6	C41 G43 T47 C54 S56 K58	C41-C45 HydrophobicContact CB-CB 3.69Å; G43-C45 PolarHBondContact O-N 3.45Å; C45-T47 VanDerWaalsContact SG-C 3.53Å; C45-T47 PolarHBondContact SG-O 3.48Å; C45-C54 VanDerWaalsContact CA-SG 3.55Å; C45-C54 HydrophobicContact CB-CB 3.84Å; C45-C54 WeakPolarHBondContact CB-SG 3.43Å; C45-C54 WeakPolarHBondContact SG-CA 3.09Å; C45-C54 WeakPolarHBondContact SG-CB 3.24Å; C45-C54 CovalentContact SG-SG 2.03Å; C45-C54 PolarHBondContact SG-SG 3.21Å; C45-S56 PolarHBondContact SG-O 3.39Å; C45-K58 WeakPolarHBondContact O-CE 3.45Å
46	A	92.1	Very high	81.2	Confident	52 Å²	52	78.7 Å²	78.7	43%	0.43	47%	0.468	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-93.8	-44	177.3	0	0	0	0	0	111.8	S56 K58	A46-S56 WeakPolarHBondContact CB-O 3.08Å; A46-S56 PolarHBondContact N-O 2.85Å; A46-K58 HydrophobicContact CB-CG 4.25Å
47	T	92.2	Very high	83.4	Confident	71 Å²	71	74.3 Å²	74.3	44%	0.436	45%	0.446	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-132.8	137.3	171.8	60.5	0	0	0	0	110.2	C45 L55 S56	C45-T47 VanDerWaalsContact SG-C 3.53Å; C45-T47 PolarHBondContact SG-O 3.48Å; T47-L55 WeakPolarHBondContact O-CA 3.39Å; T47-L55 WeakPolarHBondContact O-CB 3.38Å; T47-L55 PolarHBondContact O-N 3.38Å; T47-S56 PolarHBondContact N-O 2.98Å; T47-S56 PolarHBondContact N-OG 3.28Å; T47-S56 PolarHBondContact O-N 3.49Å; T47-S56 VanDerWaalsContact O-N 3.16Å; T47-S56 WeakPolarHBondContact OG1-CB 2.98Å; T47-S56 PolarHBondContact OG1-N 3.42Å; T47-S56 PolarHBondContact OG1-OG 3.31Å
48	C	92.9	Very high	85.6	Confident	58 Å²	58	74.3 Å²	74.3	39%	0.392	44%	0.438	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-140.5	163.4	-173.8	56.2	0	0	0	0	110.9	C41 G53	C41-C48 WeakPolarHBondContact CA-SG 3.06Å; C41-C48 HydrophobicContact CB-CB 3.67Å; C41-C48 WeakPolarHBondContact CB-SG 3.45Å; C41-C48 WeakPolarHBondContact SG-CB 3.36Å; C41-C48 PolarHBondContact SG-N 3.18Å; C41-C48 CovalentContact SG-SG 2.03Å; C41-C48 PolarHBondContact SG-SG 3.35Å; C48-G53 CarbonylContact C-O 3.54Å; C48-G53 VanDerWaalsContact CA-O 3.29Å; C48-G53 WeakPolarHBondContact CA-O 3.32Å
49	S	91.1	Very high	87.3	Confident	34 Å²	34	75.6 Å²	75.6	24%	0.238	44%	0.444	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-138.1	152.1	173.7	64.2	0	0	0	0	109.3	Y51 N52 G53	S49-Y51 PolarHBondContact O-N 3.22Å; S49-N52 WeakPolarHBondContact OG-CB 3.26Å; S49-N52 PolarHBondContact OG-N 3.29Å; S49-N52 VanDerWaalsContact OG-N 3.16Å; S49-G53 PolarHBondContact N-O 2.66Å; S49-G53 WeakPolarHBondContact O-CA 3.4Å; S49-G53 PolarHBondContact O-N 3.25Å
50	D	86.7	Confident	88.7	Confident	165 Å²	165	77.2 Å²	77.2	88%	0.882	44%	0.443	S	S	*	.	T	Hydrogen-bonded Turn	trans	-63.8	-29.4	-176.7	-57.8	-37.3	0	0	0	112.9
51	Y	87.4	Confident	89.8	Confident	194 Å²	194	76.4 Å²	76.4	76%	0.761	43%	0.425	S	S	*	.	T	Hydrogen-bonded Turn	trans	-95.9	-41.5	-175.1	-64.8	-79.2	0	0	0	114.1	S49	S49-Y51 PolarHBondContact O-N 3.22Å
52	N	90.9	Very high	90.5	Very high	94 Å²	94	75.9 Å²	75.9	50%	0.503	42%	0.419	S	S	.	.	T	Hydrogen-bonded Turn	trans	-96.3	0.8	-176	-54	-50.8	0	0	0	112.3	S49 L55 I73 G74	S49-N52 WeakPolarHBondContact OG-CB 3.26Å; S49-N52 PolarHBondContact OG-N 3.29Å; S49-N52 VanDerWaalsContact OG-N 3.16Å; N52-L55 HydrophobicContact CB-CD2 4Å; N52-I73 CarbonylContact O-C 3.52Å; N52-I73 WeakPolarHBondContact O-CA 3.25Å; N52-G74 PolarHBondContact O-N 3.4Å
53	G	91.8	Very high	91.2	Very high	22 Å²	22	69.5 Å²	69.5	23%	0.227	39%	0.389	C	S	.	.	E	Extended strand (participates in β ladder)	trans	67.2	-135.9	-173.4	0	0	0	0	0	111.3	C48 S49	C48-G53 CarbonylContact C-O 3.54Å; C48-G53 VanDerWaalsContact CA-O 3.29Å; C48-G53 WeakPolarHBondContact CA-O 3.32Å; S49-G53 PolarHBondContact N-O 2.66Å; S49-G53 WeakPolarHBondContact O-CA 3.4Å; S49-G53 PolarHBondContact O-N 3.25Å
54	C	93.2	Very high	92	Very high	10 Å²	10	67 Å²	67	7%	0.068	36%	0.361	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-72.6	138	178.5	-165.7	0	0	0	0	112.2	C45 S56 F63 G74 C76	C45-C54 VanDerWaalsContact CA-SG 3.55Å; C45-C54 HydrophobicContact CB-CB 3.84Å; C45-C54 WeakPolarHBondContact CB-SG 3.43Å; C45-C54 WeakPolarHBondContact SG-CA 3.09Å; C45-C54 WeakPolarHBondContact SG-CB 3.24Å; C45-C54 CovalentContact SG-SG 2.03Å; C45-C54 PolarHBondContact SG-SG 3.21Å; C54-S56 PolarHBondContact SG-O 3.24Å; C54-F63 VanDerWaalsContact O-CE2 3.31Å; C54-F63 WeakPolarHBondContact O-CE2 3.3Å; C54-G74 WeakPolarHBondContact CA-O 3.38Å; C54-G74 VanDerWaalsContact CB-O 3.25Å; C54-G74 WeakPolarHBondContact CB-O 3.28Å; C54-G74 PolarHBondContact N-O 3.1Å; C54-G74 WeakPolarHBondContact O-CA 3.49Å; C54-C76 PolarHBondContact SG-SG 3.33Å
55	L	91.8	Very high	92.2	Very high	89 Å²	89	69.5 Å²	69.5	47%	0.466	37%	0.369	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-104.9	-35.1	176.4	-56.8	178	0	0	0	111.8	T47 N52	T47-L55 WeakPolarHBondContact O-CA 3.39Å; T47-L55 WeakPolarHBondContact O-CB 3.38Å; T47-L55 PolarHBondContact O-N 3.38Å; N52-L55 HydrophobicContact CB-CD2 4Å
56	S	92.3	Very high	92.1	Very high	39 Å²	39	74 Å²	74	27%	0.273	39%	0.389	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-141.7	139.1	174.5	68.9	0	0	0	0	111.6	C45 A46 T47 C54	C45-S56 PolarHBondContact SG-O 3.39Å; A46-S56 WeakPolarHBondContact CB-O 3.08Å; A46-S56 PolarHBondContact N-O 2.85Å; T47-S56 PolarHBondContact N-O 2.98Å; T47-S56 PolarHBondContact N-OG 3.28Å; T47-S56 PolarHBondContact O-N 3.49Å; T47-S56 VanDerWaalsContact O-N 3.16Å; T47-S56 WeakPolarHBondContact OG1-CB 2.98Å; T47-S56 PolarHBondContact OG1-N 3.42Å; T47-S56 PolarHBondContact OG1-OG 3.31Å; C54-S56 PolarHBondContact SG-O 3.24Å
57	C	93.8	Very high	92.1	Very high	22 Å²	22	80.8 Å²	80.8	15%	0.149	40%	0.404	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-90.2	151.6	179.8	-63.4	0	0	0	0	112.1	L61 C76	C57-L61 HydrophobicContact CB-CB 4.08Å; C57-C76 WeakPolarHBondContact CA-SG 3.47Å; C57-C76 HydrophobicContact CB-CB 3.89Å; C57-C76 WeakPolarHBondContact CB-SG 3.45Å; C57-C76 VanDerWaalsContact SG-CA 3.56Å; C57-C76 WeakPolarHBondContact SG-CB 3.25Å; C57-C76 CovalentContact SG-SG 2.03Å; C57-C76 PolarHBondContact SG-SG 3.29Å
58	K	92.1	Very high	91.9	Very high	107 Å²	107	82.1 Å²	82.1	47%	0.465	41%	0.407	S	S	.	.	P	Polyproline II helix	trans	-60.3	156.1	165.2	-70.5	177.2	-172.5	179.6	0	110.5	G44 C45 A46 L61	G44-K58 VanDerWaalsContact O-CB 3.24Å; G44-K58 WeakPolarHBondContact O-CB 3.36Å; G44-K58 WeakPolarHBondContact O-CG 3.45Å; G44-K58 PolarHBondContact O-N 3.2Å; C45-K58 WeakPolarHBondContact O-CE 3.45Å; A46-K58 HydrophobicContact CB-CG 4.25Å; K58-L61 HydrophobicContact CB-CD1 4.34Å; K58-L61 PolarHBondContact O-N 3.29Å
59	P	90.4	Very high	91.8	Very high	117 Å²	117	82.2 Å²	82.2	76%	0.76	42%	0.418	S	S	*	.	T	Hydrogen-bonded Turn	trans	-51.9	148.1	178.1	-26.2	34.2	0	0	0	112.3	L61	P59-L61 PolarHBondContact O-N 3.35Å
60	R	90.8	Very high	91.7	Very high	206 Å²	206	89.6 Å²	89.6	78%	0.777	45%	0.451	S	S	*	.	T	Hydrogen-bonded Turn	trans	73.9	-15.9	-177.7	-50.6	178.9	174.7	160.5	-1.3	116.7
61	L	94.6	Very high	91.8	Very high	39 Å²	39	88.7 Å²	88.7	20%	0.204	44%	0.439	C	S	.	.			trans	-85	156	174.2	-59.5	178	0	0	0	111.2	G44 C57 K58 P59 C76 L77 N93	G44-L61 VanDerWaalsContact O-CD1 3.29Å; G44-L61 WeakPolarHBondContact O-CD1 3.44Å; C57-L61 HydrophobicContact CB-CB 4.08Å; K58-L61 HydrophobicContact CB-CD1 4.34Å; K58-L61 PolarHBondContact O-N 3.29Å; P59-L61 PolarHBondContact O-N 3.35Å; L61-C76 HydrophobicContact CB-CB 4.25Å; L61-C76 HydrophobicContact CD1-CB 4.05Å; L61-L77 WeakPolarHBondContact CA-O 3Å; L61-N93 WeakPolarHBondContact O-CB 2.95Å; L61-N93 PolarHBondContact O-ND2 3.42Å
62	F	96	Very high	92	Very high	21 Å²	21	84.9 Å²	84.9	9%	0.092	43%	0.428	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-104.5	129.1	177.1	-64.8	-90	0	0	0	110.7	C76 L77 R88 N93 C95	F62-C76 WeakPolarHBondContact O-CA 3.4Å; F62-L77 PolarHBondContact N-O 2.88Å; F62-L77 PolarHBondContact O-N 3.12Å; F62-R88 HydrophobicContact CE1-CG 4.39Å; F62-N93 CarbonylContact C-O 3.56Å; F62-N93 WeakPolarHBondContact CA-O 3.42Å; F62-N93 HydrophobicContact CD1-CB 3.51Å; F62-N93 HydrophobicContact CE1-CB 3.72Å; F62-N93 HydrophobicContact CG-CB 4.15Å; F62-C95 VanDerWaalsContact CB-SG 3.53Å
63	F	94.9	Very high	92.1	Very high	26 Å²	26	82.3 Å²	82.3	11%	0.114	41%	0.414	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-77.5	128.9	172.1	-173.8	-94.5	0	0	0	110.3	C54 L65 I92 N93 K94 C95	C54-F63 VanDerWaalsContact O-CE2 3.31Å; C54-F63 WeakPolarHBondContact O-CE2 3.3Å; F63-L65 HydrophobicContact CE1-CD1 4.36Å; F63-L65 HydrophobicContact CE1-CD2 3.63Å; F63-L65 HydrophobicContact CE1-CG 3.69Å; F63-L65 HydrophobicContact CZ-CD2 3.7Å; F63-L65 HydrophobicContact CZ-CG 4.28Å; F63-I92 HydrophobicContact CB-CD1 3.74Å; F63-I92 HydrophobicContact CB-CG1 4.11Å; F63-I92 HydrophobicContact CD1-CD1 4.39Å; F63-I92 HydrophobicContact CD2-CD1 4.33Å; F63-I92 HydrophobicContact CG-CD1 3.92Å; F63-N93 PolarHBondContact N-O 3.45Å; F63-K94 WeakPolarHBondContact O-CA 3.27Å; F63-K94 WeakPolarHBondContact O-CG 3.44Å; F63-C95 PolarHBondContact O-N 3.05Å
64	V	94.8	Very high	92.2	Very high	15 Å²	15	81.4 Å²	81.4	9%	0.091	41%	0.405	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-133.6	145.6	171.5	68.2	0	0	0	0	109.7	V75 L77 C95	V64-V75 HydrophobicContact CG1-CG2 3.51Å; V64-V75 PolarHBondContact N-O 3.06Å; V64-V75 WeakPolarHBondContact O-CG2 3.41Å; V64-V75 PolarHBondContact O-N 3.33Å; V64-L77 HydrophobicContact CG1-CD1 3.65Å; V64-L77 HydrophobicContact CG1-CG 4.01Å; V64-C95 HydrophobicContact CB-CB 4.13Å; V64-C95 HydrophobicContact CG2-CB 4.15Å
65	L	93.1	Very high	92.2	Very high	71 Å²	71	82.8 Å²	82.8	37%	0.372	41%	0.413	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-100	112.7	175.2	-69.1	167.6	0	0	0	108.6	F63 Q72 I73	F63-L65 HydrophobicContact CE1-CD1 4.36Å; F63-L65 HydrophobicContact CE1-CD2 3.63Å; F63-L65 HydrophobicContact CE1-CG 3.69Å; F63-L65 HydrophobicContact CZ-CD2 3.7Å; F63-L65 HydrophobicContact CZ-CG 4.28Å; L65-Q72 HydrophobicContact CB-CG 3.8Å; L65-Q72 HydrophobicContact CD2-CG 4.14Å; L65-Q72 HydrophobicContact CG-CG 4.37Å; L65-I73 CarbonylContact C-O 3.6Å; L65-I73 WeakPolarHBondContact CA-O 3.27Å
66	E	92.2	Very high	92.3	Very high	103 Å²	103	79.4 Å²	79.4	48%	0.481	40%	0.397	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-95.1	133.6	178.8	-169.7	167.5	-171.9	0	0	110	I68 Q72 I73 V75	E66-I68 HydrophobicContact CG-CG1 4.43Å; E66-Q72 WeakPolarHBondContact O-CA 3.26Å; E66-I73 HydrophobicContact CB-CG1 4.22Å; E66-I73 PolarHBondContact N-O 2.89Å; E66-I73 PolarHBondContact O-N 3.25Å; E66-V75 HydrophobicContact CB-CG2 3.91Å
67	R	91.9	Very high	92.4	Very high	194 Å²	194	80.7 Å²	80.7	73%	0.732	40%	0.4	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-99.2	116.5	-180	-178.7	-177.6	-113.2	-111.1	6.4	109.3	G69 K71	R67-G69 WeakPolarHBondContact CG-O 3.2Å; R67-G69 PolarHBondContact NH1-O 2.03Å; R67-K71 WeakPolarHBondContact CA-O 3.46Å
68	I	88.1	Confident	92.4	Very high	98 Å²	98	84 Å²	84	50%	0.503	42%	0.423	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-116.1	97.6	176	-54.8	176	0	0	0	107.4	E66 M70 K71 I73	E66-I68 HydrophobicContact CG-CG1 4.43Å; I68-M70 PolarHBondContact O-N 3.32Å; I68-K71 PolarHBondContact N-O 3.38Å; I68-K71 PolarHBondContact O-N 3.32Å; I68-I73 HydrophobicContact CD1-CD1 3.56Å; I68-I73 HydrophobicContact CD1-CG1 4.12Å
69	G	89.3	Confident	92.5	Very high	60 Å²	60	83 Å²	83	62%	0.619	43%	0.43	S	S	*	.	T	Hydrogen-bonded Turn	trans	63.1	-114.2	-171.6	0	0	0	0	0	111.8	R67	R67-G69 WeakPolarHBondContact CG-O 3.2Å; R67-G69 PolarHBondContact NH1-O 2.03Å
70	M	89.1	Confident	92.8	Very high	189 Å²	189	78.8 Å²	78.8	93%	0.931	40%	0.403	S	S	*	.	T	Hydrogen-bonded Turn	trans	-94.5	-9.5	175.7	-61.7	-178.6	-179	0	0	113.3	I68	I68-M70 PolarHBondContact O-N 3.32Å
71	K	89.4	Confident	92.9	Very high	147 Å²	147	71.6 Å²	71.6	64%	0.639	38%	0.383	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-88.6	145.8	-179.5	-64.4	-175.4	178.9	-177.3	0	110.6	R67 I68	R67-K71 WeakPolarHBondContact CA-O 3.46Å; I68-K71 PolarHBondContact N-O 3.38Å; I68-K71 PolarHBondContact O-N 3.32Å
72	Q	91.9	Very high	92.8	Very high	114 Å²	114	75.1 Å²	75.1	53%	0.533	41%	0.411	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-121.1	118.2	171.9	-169.2	173.3	21	0	0	108.2	L65 E66	L65-Q72 HydrophobicContact CB-CG 3.8Å; L65-Q72 HydrophobicContact CD2-CG 4.14Å; L65-Q72 HydrophobicContact CG-CG 4.37Å; E66-Q72 WeakPolarHBondContact O-CA 3.26Å
73	I	92.9	Very high	92.7	Very high	40 Å²	40	75 Å²	75	21%	0.205	42%	0.416	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-115.9	141	-178.5	62.3	165.7	0	0	0	110.2	N52 L65 E66 I68 V75	N52-I73 CarbonylContact O-C 3.52Å; N52-I73 WeakPolarHBondContact O-CA 3.25Å; L65-I73 CarbonylContact C-O 3.6Å; L65-I73 WeakPolarHBondContact CA-O 3.27Å; E66-I73 HydrophobicContact CB-CG1 4.22Å; E66-I73 PolarHBondContact N-O 2.89Å; E66-I73 PolarHBondContact O-N 3.25Å; I68-I73 HydrophobicContact CD1-CD1 3.56Å; I68-I73 HydrophobicContact CD1-CG1 4.12Å; I73-V75 HydrophobicContact CD1-CG1 4.38Å
74	G	92.8	Very high	92.7	Very high	3 Å²	3	77.8 Å²	77.8	3%	0.031	43%	0.426	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-81.7	134.8	171.8	0	0	0	0	0	111	N52 C54	N52-G74 PolarHBondContact O-N 3.4Å; C54-G74 WeakPolarHBondContact CA-O 3.38Å; C54-G74 VanDerWaalsContact CB-O 3.25Å; C54-G74 WeakPolarHBondContact CB-O 3.28Å; C54-G74 PolarHBondContact N-O 3.1Å; C54-G74 WeakPolarHBondContact O-CA 3.49Å
75	V	93.4	Very high	92.7	Very high	38 Å²	38	78.5 Å²	78.5	23%	0.23	43%	0.427	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-137.2	149.4	178.3	-83.8	0	0	0	0	109.3	V64 E66 I73	V64-V75 HydrophobicContact CG1-CG2 3.51Å; V64-V75 PolarHBondContact N-O 3.06Å; V64-V75 WeakPolarHBondContact O-CG2 3.41Å; V64-V75 PolarHBondContact O-N 3.33Å; E66-V75 HydrophobicContact CB-CG2 3.91Å; I73-V75 HydrophobicContact CD1-CG1 4.38Å
76	C	94.6	Very high	92.9	Very high	19 Å²	19	76.8 Å²	76.8	13%	0.128	43%	0.427	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-111.2	121.9	-178.4	-62.1	0	0	0	0	110.2	C54 C57 L61 F62	C54-C76 PolarHBondContact SG-SG 3.33Å; C57-C76 WeakPolarHBondContact CA-SG 3.47Å; C57-C76 HydrophobicContact CB-CB 3.89Å; C57-C76 WeakPolarHBondContact CB-SG 3.45Å; C57-C76 VanDerWaalsContact SG-CA 3.56Å; C57-C76 WeakPolarHBondContact SG-CB 3.25Å; C57-C76 CovalentContact SG-SG 2.03Å; C57-C76 PolarHBondContact SG-SG 3.29Å; L61-C76 HydrophobicContact CB-CB 4.25Å; L61-C76 HydrophobicContact CD1-CB 4.05Å; F62-C76 WeakPolarHBondContact O-CA 3.4Å
77	L	94.8	Very high	93	Very high	65 Å²	65	73.1 Å²	73.1	34%	0.34	41%	0.412	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-118.5	151.2	-178.7	-57.3	178.6	0	0	0	111.2	L61 F62 V64 S79	L61-L77 WeakPolarHBondContact CA-O 3Å; F62-L77 PolarHBondContact N-O 2.88Å; F62-L77 PolarHBondContact O-N 3.12Å; V64-L77 HydrophobicContact CG1-CD1 3.65Å; V64-L77 HydrophobicContact CG1-CG 4.01Å; L77-S79 VanDerWaalsContact C-N 3.29Å; L77-S79 WeakPolarHBondContact CB-O 3.09Å
78	S	94.1	Very high	93	Very high	92 Å²	92	71.8 Å²	71.8	64%	0.643	41%	0.407	S	S	*	.	S	Bend	trans	-73.7	-23.5	172.2	54.1	0	0	0	0	112.5
79	S	94.1	Very high	93.1	Very high	85 Å²	85	72.7 Å²	72.7	59%	0.594	41%	0.405	S	S	*	.	S	Bend	trans	-148.1	147.2	178.3	-67.2	0	0	0	0	109.7	L77	L77-S79 VanDerWaalsContact C-N 3.29Å; L77-S79 WeakPolarHBondContact CB-O 3.09Å
80	C	95.1	Very high	93.1	Very high	30 Å²	30	76 Å²	76	20%	0.203	42%	0.415	C	S	.	.	P	Polyproline II helix	trans	-71.5	146.2	-179	-67.5	0	0	0	0	111.7	G86 C95	C80-G86 VanDerWaalsContact SG-CA 3.53Å; C80-C95 WeakPolarHBondContact CA-SG 3.31Å; C80-C95 HydrophobicContact CB-CB 3.82Å; C80-C95 WeakPolarHBondContact CB-SG 3.44Å; C80-C95 WeakPolarHBondContact SG-CA 3.28Å; C80-C95 WeakPolarHBondContact SG-CB 3.48Å; C80-C95 CovalentContact SG-SG 2.04Å; C80-C95 PolarHBondContact SG-SG 2.93Å
81	P	94.2	Very high	92.9	Very high	54 Å²	54	74.5 Å²	74.5	35%	0.351	41%	0.411	S	S	.	.	P	Polyproline II helix	trans	-68.4	166.4	177.1	30	-35.4	0	0	0	111.7	G83 Y84	P81-G83 PolarHBondContact O-N 2.86Å; P81-Y84 HydrophobicContact CG-CD2 3.98Å; P81-Y84 HydrophobicContact CG-CG 4.3Å; P81-Y84 WeakPolarHBondContact O-CB 3.26Å; P81-Y84 PolarHBondContact O-N 3.26Å
82	S	92.3	Very high	92.9	Very high	113 Å²	113	70.5 Å²	70.5	79%	0.79	40%	0.396	S	S	*	.	T	Hydrogen-bonded Turn	trans	-52.9	138.3	177	-55.6	0	0	0	0	112	Y84	S82-Y84 VanDerWaalsContact C-N 3.3Å
83	G	93.3	Very high	93	Very high	20 Å²	20	66.2 Å²	66.2	21%	0.206	38%	0.377	C	S	.	.	T	Hydrogen-bonded Turn	trans	79.7	5.2	-174.2	0	0	0	0	0	115	P81 C98 D103	P81-G83 PolarHBondContact O-N 2.86Å; G83-C98 VanDerWaalsContact C-SG 3.57Å; G83-C98 WeakPolarHBondContact O-CB 3.38Å; G83-C98 PolarHBondContact O-N 3.42Å; G83-C98 PolarHBondContact O-SG 2.89Å; G83-D103 WeakPolarHBondContact CA-O 3.37Å; G83-D103 PolarHBondContact N-O 2.84Å
84	Y	95.3	Very high	93.1	Very high	84 Å²	84	68.5 Å²	68.5	33%	0.329	39%	0.385	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-128.8	147.4	174.9	-67.7	-107.2	0	0	0	111.4	P81 S82 C95 T96 K97	P81-Y84 HydrophobicContact CG-CD2 3.98Å; P81-Y84 HydrophobicContact CG-CG 4.3Å; P81-Y84 WeakPolarHBondContact O-CB 3.26Å; P81-Y84 PolarHBondContact O-N 3.26Å; S82-Y84 VanDerWaalsContact C-N 3.3Å; Y84-C95 HydrophobicContact CD1-CB 4.12Å; Y84-C95 HydrophobicContact CG-CB 4.44Å; Y84-T96 CarbonylContact C-O 3.57Å; Y84-T96 VanDerWaalsContact CA-O 3.22Å; Y84-T96 WeakPolarHBondContact CA-O 3.44Å; Y84-T96 VanDerWaalsContact CD1-C 3.47Å; Y84-K97 HydrophobicContact CD1-CB 4.02Å; Y84-K97 HydrophobicContact CE1-CB 3.7Å; Y84-K97 HydrophobicContact CE1-CG 4.16Å; Y84-K97 HydrophobicContact CE2-CG 4.31Å
85	Y	95.9	Very high	93.2	Very high	29 Å²	29	68.6 Å²	68.6	11%	0.114	39%	0.386	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-117.4	148.4	171.8	71.3	-81.1	0	0	0	110.7	T87 T96 C105 K108	Y85-T87 WeakPolarHBondContact CE2-OG1 3.49Å; Y85-T96 WeakPolarHBondContact CD1-O 3.46Å; Y85-T96 HydrophobicContact CE1-CG2 3.74Å; Y85-T96 PolarHBondContact N-O 2.91Å; Y85-T96 PolarHBondContact O-N 3.41Å; Y85-T96 WeakPolarHBondContact OH-CG2 3.29Å; Y85-C105 WeakPolarHBondContact CB-O 3.42Å; Y85-C105 WeakPolarHBondContact CD1-SG 3.03Å; Y85-K108 WeakPolarHBondContact OH-CB 3.46Å
86	G	95.5	Very high	93.3	Very high	36 Å²	36	68.5 Å²	68.5	37%	0.371	39%	0.385	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-76.7	124.5	179.1	0	0	0	0	0	111.8	C80	C80-G86 VanDerWaalsContact SG-CA 3.53Å
87	T	94.4	Very high	93.3	Very high	26 Å²	26	74.6 Å²	74.6	16%	0.16	41%	0.409	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-111.4	129.1	171.4	-48.8	0	0	0	0	109.3	Y85 Y89 N93 K94 T96	Y85-T87 WeakPolarHBondContact CE2-OG1 3.49Å; T87-Y89 HydrophobicContact CG2-CD2 4.16Å; T87-Y89 HydrophobicContact CG2-CE1 4.03Å; T87-Y89 HydrophobicContact CG2-CE2 3.53Å; T87-Y89 VanDerWaalsContact CG2-CZ 3.46Å; T87-N93 CarbonylContact O-C 3.51Å; T87-N93 VanDerWaalsContact O-CA 3.27Å; T87-N93 WeakPolarHBondContact O-CA 3.41Å; T87-K94 PolarHBondContact N-O 3.46Å; T87-K94 PolarHBondContact O-N 2.91Å; T87-T96 PolarHBondContact OG1-OG1 3.25Å
88	R	92.7	Very high	93.3	Very high	166 Å²	166	72.1 Å²	72.1	63%	0.626	40%	0.397	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-101.3	106.1	178.9	-59.2	-176.3	177.8	-95.1	0.4	109.1	F62 N93	F62-R88 HydrophobicContact CE1-CG 4.39Å; R88-N93 WeakPolarHBondContact CA-OD1 2.99Å; R88-N93 WeakPolarHBondContact CB-OD1 3.5Å; R88-N93 VanDerWaalsContact CG-OD1 3.3Å; R88-N93 WeakPolarHBondContact CG-OD1 3.4Å
89	Y	89.9	Confident	93.3	Very high	117 Å²	117	72.5 Å²	72.5	46%	0.459	39%	0.388	S	S	.	.			trans	-92.4	162	170.6	-58.6	-83.6	0	0	0	109.7	T87 D91 I92 K94	T87-Y89 HydrophobicContact CG2-CD2 4.16Å; T87-Y89 HydrophobicContact CG2-CE1 4.03Å; T87-Y89 HydrophobicContact CG2-CE2 3.53Å; T87-Y89 VanDerWaalsContact CG2-CZ 3.46Å; Y89-D91 PolarHBondContact O-N 2.89Å; Y89-I92 WeakPolarHBondContact CA-O 3.39Å; Y89-I92 WeakPolarHBondContact CB-O 3.23Å; Y89-I92 HydrophobicContact CD2-CG2 4.48Å; Y89-I92 WeakPolarHBondContact CD2-O 3.27Å; Y89-I92 PolarHBondContact N-O 2.01Å; Y89-K94 HydrophobicContact CE2-CB 4.29Å
90	P	89.1	Confident	93.3	Very high	129 Å²	129	72.5 Å²	72.5	84%	0.838	39%	0.393	S	S	*	.	S	Bend	trans	-52.4	-37.1	176.7	-28.2	36.5	0	0	0	113.1
91	D	85.3	Confident	93.2	Very high	158 Å²	158	72.9 Å²	72.9	85%	0.845	39%	0.393	S	S	*	.	S	Bend	trans	-101.6	-25.2	-172.6	-49.8	-52.2	0	0	0	113.9	Y89	Y89-D91 PolarHBondContact O-N 2.89Å
92	I	89.5	Confident	93.3	Very high	62 Å²	62	70.7 Å²	70.7	32%	0.318	38%	0.379	S	S	.	.			trans	-155.3	140.7	-174.6	-166.7	167.6	0	0	0	111.8	F63 Y89	F63-I92 HydrophobicContact CB-CD1 3.74Å; F63-I92 HydrophobicContact CB-CG1 4.11Å; F63-I92 HydrophobicContact CD1-CD1 4.39Å; F63-I92 HydrophobicContact CD2-CD1 4.33Å; F63-I92 HydrophobicContact CG-CD1 3.92Å; Y89-I92 WeakPolarHBondContact CA-O 3.39Å; Y89-I92 WeakPolarHBondContact CB-O 3.23Å; Y89-I92 HydrophobicContact CD2-CG2 4.48Å; Y89-I92 WeakPolarHBondContact CD2-O 3.27Å; Y89-I92 PolarHBondContact N-O 2.01Å
93	N	94.3	Very high	93.4	Very high	25 Å²	25	68 Å²	68	13%	0.134	36%	0.355	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-91.6	129.8	165.4	-42.6	-66.2	0	0	0	108.4	L61 F62 F63 T87 R88	L61-N93 WeakPolarHBondContact O-CB 2.95Å; L61-N93 PolarHBondContact O-ND2 3.42Å; F62-N93 CarbonylContact C-O 3.56Å; F62-N93 WeakPolarHBondContact CA-O 3.42Å; F62-N93 HydrophobicContact CD1-CB 3.51Å; F62-N93 HydrophobicContact CE1-CB 3.72Å; F62-N93 HydrophobicContact CG-CB 4.15Å; F63-N93 PolarHBondContact N-O 3.45Å; T87-N93 CarbonylContact O-C 3.51Å; T87-N93 VanDerWaalsContact O-CA 3.27Å; T87-N93 WeakPolarHBondContact O-CA 3.41Å; R88-N93 WeakPolarHBondContact CA-OD1 2.99Å; R88-N93 WeakPolarHBondContact CB-OD1 3.5Å; R88-N93 VanDerWaalsContact CG-OD1 3.3Å; R88-N93 WeakPolarHBondContact CG-OD1 3.4Å
94	K	94.8	Very high	93.5	Very high	87 Å²	87	69.2 Å²	69.2	38%	0.378	36%	0.359	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-128.6	145.9	-177.1	-173.5	179	178.4	178.8	0	110.8	F63 T87 Y89	F63-K94 WeakPolarHBondContact O-CA 3.27Å; F63-K94 WeakPolarHBondContact O-CG 3.44Å; T87-K94 PolarHBondContact N-O 3.46Å; T87-K94 PolarHBondContact O-N 2.91Å; Y89-K94 HydrophobicContact CE2-CB 4.29Å
95	C	95.5	Very high	93.5	Very high	6 Å²	6	66.1 Å²	66.1	4%	0.041	35%	0.349	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-80.9	120.1	167.9	-64.5	0	0	0	0	110.4	F62 F63 V64 C80 Y84	F62-C95 VanDerWaalsContact CB-SG 3.53Å; F63-C95 PolarHBondContact O-N 3.05Å; V64-C95 HydrophobicContact CB-CB 4.13Å; V64-C95 HydrophobicContact CG2-CB 4.15Å; C80-C95 WeakPolarHBondContact CA-SG 3.31Å; C80-C95 HydrophobicContact CB-CB 3.82Å; C80-C95 WeakPolarHBondContact CB-SG 3.44Å; C80-C95 WeakPolarHBondContact SG-CA 3.28Å; C80-C95 WeakPolarHBondContact SG-CB 3.48Å; C80-C95 CovalentContact SG-SG 2.04Å; C80-C95 PolarHBondContact SG-SG 2.93Å; Y84-C95 HydrophobicContact CD1-CB 4.12Å; Y84-C95 HydrophobicContact CG-CB 4.44Å
96	T	94.6	Very high	93.4	Very high	36 Å²	36	72 Å²	72	22%	0.221	38%	0.376	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-107.4	135.8	179.1	-56.1	0	0	0	0	109.1	Y84 Y85 T87	Y84-T96 CarbonylContact C-O 3.57Å; Y84-T96 VanDerWaalsContact CA-O 3.22Å; Y84-T96 WeakPolarHBondContact CA-O 3.44Å; Y84-T96 VanDerWaalsContact CD1-C 3.47Å; Y85-T96 WeakPolarHBondContact CD1-O 3.46Å; Y85-T96 HydrophobicContact CE1-CG2 3.74Å; Y85-T96 PolarHBondContact N-O 2.91Å; Y85-T96 PolarHBondContact O-N 3.41Å; Y85-T96 WeakPolarHBondContact OH-CG2 3.29Å; T87-T96 PolarHBondContact OG1-OG1 3.25Å
97	K	94.4	Very high	93.4	Very high	146 Å²	146	73.1 Å²	73.1	64%	0.635	37%	0.373	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-67.3	140.1	-178.2	-163.9	176.7	179.9	175.8	0	110.6	Y84	Y84-K97 HydrophobicContact CD1-CB 4.02Å; Y84-K97 HydrophobicContact CE1-CB 3.7Å; Y84-K97 HydrophobicContact CE1-CG 4.16Å; Y84-K97 HydrophobicContact CE2-CG 4.31Å
98	C	95.6	Very high	93.2	Very high	13 Å²	13	78.6 Å²	78.6	9%	0.088	40%	0.395	C	S	.	.	P	Polyproline II helix	trans	-63.5	165	169.7	-62.8	0	0	0	0	111.2	G83 C102 C105	G83-C98 VanDerWaalsContact C-SG 3.57Å; G83-C98 WeakPolarHBondContact O-CB 3.38Å; G83-C98 PolarHBondContact O-N 3.42Å; G83-C98 PolarHBondContact O-SG 2.89Å; C98-C102 HydrophobicContact CB-CB 4.37Å; C98-C105 WeakPolarHBondContact CA-SG 3.03Å; C98-C105 HydrophobicContact CB-CB 3.93Å; C98-C105 WeakPolarHBondContact CB-SG 3.39Å; C98-C105 WeakPolarHBondContact SG-CB 3.35Å; C98-C105 PolarHBondContact SG-N 3.45Å; C98-C105 CovalentContact SG-SG 2.04Å; C98-C105 PolarHBondContact SG-SG 2.93Å
99	K	94.2	Very high	93.2	Very high	101 Å²	101	76 Å²	76	44%	0.439	39%	0.393	S	S	.	.	P	Polyproline II helix	trans	-64.1	161.3	174	-66	178.8	173.5	168	0	111.7	D101 C102 K108	K99-D101 VanDerWaalsContact C-N 3.26Å; K99-D101 WeakPolarHBondContact CB-OD1 3.23Å; K99-D101 PolarHBondContact O-N 2.97Å; K99-C102 PolarHBondContact O-N 3.46Å; K99-C102 VanDerWaalsContact O-N 3.15Å; K99-K108 WeakPolarHBondContact CE-O 3.41Å; K99-K108 PolarHBondContact NZ-O 2.8Å
100	A	92.8	Very high	93.5	Very high	85 Å²	85	75 Å²	75	70%	0.702	39%	0.392	S	S	*	.	T	Hydrogen-bonded Turn	trans	-64.8	-27.6	-171.9	0	0	0	0	0	114.2	K115	A100-K115 WeakPolarHBondContact O-CD 3.38Å; A100-K115 WeakPolarHBondContact O-CE 3.2Å; A100-K115 PolarHBondContact O-NZ 3.49Å
101	D	94.4	Very high	93.8	Very high	38 Å²	38	69.3 Å²	69.3	20%	0.203	35%	0.354	C	S	.	.	T	Hydrogen-bonded Turn	trans	-85.3	-9.8	178.8	54.8	-33.1	0	0	0	113.6	K99 K115 F118 C125	K99-D101 VanDerWaalsContact C-N 3.26Å; K99-D101 WeakPolarHBondContact CB-OD1 3.23Å; K99-D101 PolarHBondContact O-N 2.97Å; D101-K115 PolarHBondContact O-N 3.3Å; D101-F118 HydrophobicContact CB-CD1 3.99Å; D101-F118 HydrophobicContact CB-CE1 3.87Å; D101-F118 HydrophobicContact CB-CE2 4.47Å; D101-F118 HydrophobicContact CB-CG 4.34Å; D101-F118 HydrophobicContact CB-CZ 4.14Å; D101-C125 HydrophobicContact CB-CB 3.89Å; D101-C125 PolarHBondContact O-SG 3.36Å; D101-C125 WeakPolarHBondContact OD2-CB 3.37Å
102	C	95.6	Very high	94.2	Very high	8 Å²	8	65.1 Å²	65.1	5%	0.054	34%	0.335	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-113.1	133.2	-172.1	-175.7	0	0	0	0	112.2	C98 K99 T104 C111 K115	C98-C102 HydrophobicContact CB-CB 4.37Å; K99-C102 PolarHBondContact O-N 3.46Å; K99-C102 VanDerWaalsContact O-N 3.15Å; C102-T104 PolarHBondContact SG-O 2.91Å; C102-C111 VanDerWaalsContact CA-SG 3.6Å; C102-C111 HydrophobicContact CB-CB 3.95Å; C102-C111 WeakPolarHBondContact CB-SG 3.25Å; C102-C111 VanDerWaalsContact SG-CA 3.57Å; C102-C111 WeakPolarHBondContact SG-CB 3.39Å; C102-C111 CovalentContact SG-SG 2.03Å; C102-C111 PolarHBondContact SG-SG 3.29Å; C102-K115 WeakPolarHBondContact O-CE 3.45Å
103	D	94.7	Very high	94.4	Very high	55 Å²	55	67.7 Å²	67.7	29%	0.294	34%	0.343	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-85.9	-51.6	176.8	-172.4	33.7	0	0	0	110.6	G83 K113 K115	G83-D103 WeakPolarHBondContact CA-O 3.37Å; G83-D103 PolarHBondContact N-O 2.84Å; D103-K113 WeakPolarHBondContact CA-O 3.45Å; D103-K113 HydrophobicContact CB-CG 4.46Å; D103-K113 WeakPolarHBondContact CB-O 3.44Å; D103-K113 PolarHBondContact N-O 2.66Å; D103-K113 WeakPolarHBondContact OD2-CE 3.33Å; D103-K113 IonicContact OD2-NZ 2.66Å; D103-K113 PolarHBondContact OD2-NZ 3.41Å; D103-K115 HydrophobicContact CB-CG 4.17Å
104	T	94.6	Very high	94.5	Very high	47 Å²	47	67 Å²	67	29%	0.288	34%	0.341	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-128.4	133	174.2	64.2	0	0	0	0	110.6	C102 C111 T112 K113	C102-T104 PolarHBondContact SG-O 2.91Å; T104-C111 PolarHBondContact O-SG 2.9Å; T104-T112 VanDerWaalsContact C-OG1 3.28Å; T104-T112 PolarHBondContact O-N 2.89Å; T104-T112 PolarHBondContact O-OG1 2.65Å; T104-T112 PolarHBondContact OG1-OG1 3.03Å; T104-K113 PolarHBondContact N-O 2.97Å; T104-K113 VanDerWaalsContact N-O 3.14Å; T104-K113 PolarHBondContact O-N 3.06Å; T104-K113 VanDerWaalsContact O-N 3.09Å; T104-K113 WeakPolarHBondContact OG1-CB 3.37Å; T104-K113 PolarHBondContact OG1-N 2.95Å
105	C	95.6	Very high	94.5	Very high	19 Å²	19	67 Å²	67	13%	0.128	34%	0.341	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-129.9	145.6	-179.3	65	0	0	0	0	111.5	Y85 C98 F110	Y85-C105 WeakPolarHBondContact CB-O 3.42Å; Y85-C105 WeakPolarHBondContact CD1-SG 3.03Å; C98-C105 WeakPolarHBondContact CA-SG 3.03Å; C98-C105 HydrophobicContact CB-CB 3.93Å; C98-C105 WeakPolarHBondContact CB-SG 3.39Å; C98-C105 WeakPolarHBondContact SG-CB 3.35Å; C98-C105 PolarHBondContact SG-N 3.45Å; C98-C105 CovalentContact SG-SG 2.04Å; C98-C105 PolarHBondContact SG-SG 2.93Å; C105-F110 WeakPolarHBondContact CA-O 2.99Å; C105-F110 WeakPolarHBondContact CB-O 3.33Å
106	F	94.5	Very high	94.3	Very high	153 Å²	153	71.6 Å²	71.6	67%	0.671	37%	0.373	S	S	*	.	S	Bend	trans	-82.6	-40.8	173.7	177.8	-104.9	0	0	0	110.9	F110 T112	F106-F110 HydrophobicContact CB-CB 4.47Å; F106-F110 HydrophobicContact CB-CD1 3.95Å; F106-F110 PolarHBondContact N-O 2.81Å; F106-T112 HydrophobicContact CB-CG2 4.27Å
107	N	93.9	Very high	94.1	Very high	59 Å²	59	72.4 Å²	72.4	32%	0.316	39%	0.388	S	S	.	.	S	Bend	trans	-148.8	-175.5	175.1	66.7	41.7	0	0	0	110.2	N109 F110	N107-N109 PolarHBondContact O-N 2.64Å; N107-N109 VanDerWaalsContact O-N 3.11Å; N107-N109 WeakPolarHBondContact OD1-CA 3.28Å; N107-N109 PolarHBondContact OD1-N 2.75Å; N107-F110 PolarHBondContact N-O 2.04Å; N107-F110 PolarHBondContact O-N 3.48Å; N107-F110 WeakPolarHBondContact OD1-CB 3.16Å; N107-F110 PolarHBondContact OD1-N 2.79Å
108	K	91.8	Very high	94.2	Very high	141 Å²	141	67.9 Å²	67.9	61%	0.613	37%	0.369	S	S	*	.	S	Bend	trans	-54.9	-31.5	179.9	-169.7	176.1	175.9	-178.2	0	114.1	Y85 K99	Y85-K108 WeakPolarHBondContact OH-CB 3.46Å; K99-K108 WeakPolarHBondContact CE-O 3.41Å; K99-K108 PolarHBondContact NZ-O 2.8Å
109	N	92.2	Very high	94.2	Very high	110 Å²	110	69.5 Å²	69.5	59%	0.588	37%	0.373	S	S	*	.	S	Bend	trans	-107.6	-14.3	-171.5	-67.1	-21.7	0	0	0	113.7	N107	N107-N109 PolarHBondContact O-N 2.64Å; N107-N109 VanDerWaalsContact O-N 3.11Å; N107-N109 WeakPolarHBondContact OD1-CA 3.28Å; N107-N109 PolarHBondContact OD1-N 2.75Å
110	F	95.6	Very high	94.2	Very high	98 Å²	98	66.2 Å²	66.2	43%	0.43	36%	0.36	S	S	.	.			trans	-121.7	104.2	-173	-163.1	-82.6	0	0	0	110.1	C105 F106 N107 T112 G123	C105-F110 WeakPolarHBondContact CA-O 2.99Å; C105-F110 WeakPolarHBondContact CB-O 3.33Å; F106-F110 HydrophobicContact CB-CB 4.47Å; F106-F110 HydrophobicContact CB-CD1 3.95Å; F106-F110 PolarHBondContact N-O 2.81Å; N107-F110 PolarHBondContact N-O 2.04Å; N107-F110 PolarHBondContact O-N 3.48Å; N107-F110 WeakPolarHBondContact OD1-CB 3.16Å; N107-F110 PolarHBondContact OD1-N 2.79Å; F110-T112 HydrophobicContact CD1-CG2 4.21Å; F110-T112 HydrophobicContact CE1-CG2 4.06Å; F110-G123 CarbonylContact C-O 3.59Å; F110-G123 WeakPolarHBondContact CA-O 2.98Å
111	C	95.9	Very high	94.3	Very high	8 Å²	8	64.4 Å²	64.4	5%	0.054	34%	0.337	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-85.9	136.2	170.6	-167.3	0	0	0	0	110	C102 T104 K113 L120 G123 C125	C102-C111 VanDerWaalsContact CA-SG 3.6Å; C102-C111 HydrophobicContact CB-CB 3.95Å; C102-C111 WeakPolarHBondContact CB-SG 3.25Å; C102-C111 VanDerWaalsContact SG-CA 3.57Å; C102-C111 WeakPolarHBondContact SG-CB 3.39Å; C102-C111 CovalentContact SG-SG 2.03Å; C102-C111 PolarHBondContact SG-SG 3.29Å; T104-C111 PolarHBondContact O-SG 2.9Å; C111-K113 PolarHBondContact SG-O 2.83Å; C111-L120 HydrophobicContact CB-CD1 4.27Å; C111-L120 WeakPolarHBondContact O-CD1 3.04Å; C111-G123 WeakPolarHBondContact CB-O 3.44Å; C111-G123 PolarHBondContact N-O 2.97Å; C111-G123 WeakPolarHBondContact O-CA 3.14Å; C111-C125 PolarHBondContact SG-SG 2.7Å
112	T	94.3	Very high	94.3	Very high	71 Å²	71	69.5 Å²	69.5	44%	0.436	36%	0.364	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-98.4	-25.8	174.6	45.3	0	0	0	0	112.1	T104 F106 F110	T104-T112 VanDerWaalsContact C-OG1 3.28Å; T104-T112 PolarHBondContact O-N 2.89Å; T104-T112 PolarHBondContact O-OG1 2.65Å; T104-T112 PolarHBondContact OG1-OG1 3.03Å; F106-T112 HydrophobicContact CB-CG2 4.27Å; F110-T112 HydrophobicContact CD1-CG2 4.21Å; F110-T112 HydrophobicContact CE1-CG2 4.06Å
113	K	94	Very high	94.1	Very high	115 Å²	115	69.4 Å²	69.4	50%	0.5	36%	0.364	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-147.5	123.9	177.2	-170.5	-175.1	169.2	-146.7	0	110.3	D103 T104 C111	D103-K113 WeakPolarHBondContact CA-O 3.45Å; D103-K113 HydrophobicContact CB-CG 4.46Å; D103-K113 WeakPolarHBondContact CB-O 3.44Å; D103-K113 PolarHBondContact N-O 2.66Å; D103-K113 WeakPolarHBondContact OD2-CE 3.33Å; D103-K113 IonicContact OD2-NZ 2.66Å; D103-K113 PolarHBondContact OD2-NZ 3.41Å; T104-K113 PolarHBondContact N-O 2.97Å; T104-K113 VanDerWaalsContact N-O 3.14Å; T104-K113 PolarHBondContact O-N 3.06Å; T104-K113 VanDerWaalsContact O-N 3.09Å; T104-K113 WeakPolarHBondContact OG1-CB 3.37Å; T104-K113 PolarHBondContact OG1-N 2.95Å; C111-K113 PolarHBondContact SG-O 2.83Å
114	C	95.2	Very high	94.1	Very high	11 Å²	11	72.9 Å²	72.9	7%	0.074	38%	0.376	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-79.9	158.1	177.9	-63.4	0	0	0	0	112	F118 L120 C125	C114-F118 HydrophobicContact CB-CB 3.96Å; C114-L120 VanDerWaalsContact SG-CA 3.53Å; C114-C125 WeakPolarHBondContact CA-SG 3.32Å; C114-C125 HydrophobicContact CB-CB 3.77Å; C114-C125 WeakPolarHBondContact CB-SG 3.1Å; C114-C125 WeakPolarHBondContact SG-CA 3.42Å; C114-C125 WeakPolarHBondContact SG-CB 3.22Å; C114-C125 CovalentContact SG-SG 2.03Å; C114-C125 PolarHBondContact SG-SG 2.95Å
115	K	94.1	Very high	94.2	Very high	87 Å²	87	71 Å²	71	38%	0.378	37%	0.365	S	S	.	.	P	Polyproline II helix	trans	-70.7	157.8	169.1	-68	-171.8	-174.7	174	0	110.5	A100 D101 C102 D103 G117 F118	A100-K115 WeakPolarHBondContact O-CD 3.38Å; A100-K115 WeakPolarHBondContact O-CE 3.2Å; A100-K115 PolarHBondContact O-NZ 3.49Å; D101-K115 PolarHBondContact O-N 3.3Å; C102-K115 WeakPolarHBondContact O-CE 3.45Å; D103-K115 HydrophobicContact CB-CG 4.17Å; K115-G117 PolarHBondContact O-N 3.29Å; K115-F118 HydrophobicContact CB-CD2 4.23Å; K115-F118 PolarHBondContact O-N 3.01Å; K115-F118 VanDerWaalsContact O-N 3.07Å
116	S	91.9	Very high	94.1	Very high	103 Å²	103	72.8 Å²	72.8	72%	0.72	37%	0.373	S	S	*	.	T	Hydrogen-bonded Turn	trans	-53.9	131.9	175.8	-52.8	0	0	0	0	111.1
117	G	91.3	Very high	94.1	Very high	52 Å²	52	71 Å²	71	54%	0.536	37%	0.37	S	S	.	.	T	Hydrogen-bonded Turn	trans	95.7	-10.8	-176.3	0	0	0	0	0	114.6	K115	K115-G117 PolarHBondContact O-N 3.29Å
118	F	94.9	Very high	94.1	Very high	52 Å²	52	72.4 Å²	72.4	23%	0.228	39%	0.385	C	S	.	.			trans	-111.7	146.3	174.6	-63.1	-95.8	0	0	0	111.1	D101 C114 K115 C125 L126 D127	D101-F118 HydrophobicContact CB-CD1 3.99Å; D101-F118 HydrophobicContact CB-CE1 3.87Å; D101-F118 HydrophobicContact CB-CE2 4.47Å; D101-F118 HydrophobicContact CB-CG 4.34Å; D101-F118 HydrophobicContact CB-CZ 4.14Å; C114-F118 HydrophobicContact CB-CB 3.96Å; K115-F118 HydrophobicContact CB-CD2 4.23Å; K115-F118 PolarHBondContact O-N 3.01Å; K115-F118 VanDerWaalsContact O-N 3.07Å; F118-C125 HydrophobicContact CB-CB 3.92Å; F118-C125 HydrophobicContact CD1-CB 4.4Å; F118-C125 HydrophobicContact CG-CB 4.37Å; F118-L126 CarbonylContact C-O 3.55Å; F118-L126 WeakPolarHBondContact CA-O 2.9Å; F118-D127 WeakPolarHBondContact CD1-OD1 3.49Å; F118-D127 WeakPolarHBondContact CE1-OD1 3.35Å; F118-D127 WeakPolarHBondContact CZ-OD1 3.32Å
119	Y	95.6	Very high	94.1	Very high	46 Å²	46	66.9 Å²	66.9	18%	0.18	36%	0.364	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-103.4	132.4	177.1	-58.6	-85.2	0	0	0	111.1	C125 L126 A135 N137 M140 C142	Y119-C125 WeakPolarHBondContact O-CA 3.48Å; Y119-L126 PolarHBondContact N-O 3.37Å; Y119-L126 PolarHBondContact O-N 2.85Å; Y119-A135 HydrophobicContact CD1-CB 3.86Å; Y119-A135 HydrophobicContact CD2-CB 4.43Å; Y119-A135 HydrophobicContact CE1-CB 3.5Å; Y119-A135 HydrophobicContact CE2-CB 4.1Å; Y119-A135 HydrophobicContact CG-CB 4.32Å; Y119-N137 PolarHBondContact OH-OD1 3.02Å; Y119-M140 CarbonylContact C-O 3.56Å; Y119-M140 WeakPolarHBondContact CA-O 3.47Å; Y119-C142 VanDerWaalsContact CB-SG 3.53Å
120	L	95.6	Very high	94.2	Very high	33 Å²	33	64.2 Å²	64.2	17%	0.173	35%	0.353	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-76.8	127.3	176.6	-176.5	68.3	0	0	0	110.7	C111 C114 K124 M140 E141 C142	C111-L120 HydrophobicContact CB-CD1 4.27Å; C111-L120 WeakPolarHBondContact O-CD1 3.04Å; C114-L120 VanDerWaalsContact SG-CA 3.53Å; L120-K124 WeakPolarHBondContact CA-O 3.46Å; L120-M140 PolarHBondContact N-O 3.19Å; L120-E141 HydrophobicContact CB-CG 4.21Å; L120-C142 PolarHBondContact O-N 2.92Å
121	H	95.3	Very high	93.9	Very high	47 Å²	47	69.1 Å²	69.1	22%	0.218	38%	0.377	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-144	118.5	173.3	-174.8	59.8	0	0	0	110.6	G123 K124 L126 L133 C142	H121-G123 PolarHBondContact O-N 2.93Å; H121-G123 VanDerWaalsContact O-N 3.15Å; H121-K124 PolarHBondContact N-O 2.95Å; H121-K124 PolarHBondContact O-N 3.47Å; H121-L126 HydrophobicContact CB-CD1 4.02Å; H121-L133 WeakPolarHBondContact CE1-CD1 3.47Å; H121-L133 VanDerWaalsContact ND1-CD1 3.33Å; H121-L133 WeakPolarHBondContact ND1-CD1 3.49Å; H121-C142 HydrophobicContact CB-CB 3.95Å
122	L	92.7	Very high	93.3	Very high	145 Å²	145	71.2 Å²	71.2	76%	0.759	40%	0.4	S	S	*	.	T	Hydrogen-bonded Turn	trans	49.7	39.8	178.9	-60.9	174.3	0	0	0	113.8	K124	L122-K124 VanDerWaalsContact C-N 3.33Å; L122-K124 PolarHBondContact O-N 3.15Å
123	G	92.9	Very high	93.2	Very high	6 Å²	6	69.5 Å²	69.5	6%	0.062	39%	0.388	C	S	.	.	T	Hydrogen-bonded Turn	trans	77.8	11.6	-179	0	0	0	0	0	114.8	F110 C111 H121	F110-G123 CarbonylContact C-O 3.59Å; F110-G123 WeakPolarHBondContact CA-O 2.98Å; C111-G123 WeakPolarHBondContact CB-O 3.44Å; C111-G123 PolarHBondContact N-O 2.97Å; C111-G123 WeakPolarHBondContact O-CA 3.14Å; H121-G123 PolarHBondContact O-N 2.93Å; H121-G123 VanDerWaalsContact O-N 3.15Å
124	K	94.8	Very high	93.1	Very high	127 Å²	127	65.1 Å²	65.1	55%	0.552	37%	0.37	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-118.4	151.1	173.6	-62.4	179.9	-176.3	175	0	110.2	L120 H121 L122	L120-K124 WeakPolarHBondContact CA-O 3.46Å; H121-K124 PolarHBondContact N-O 2.95Å; H121-K124 PolarHBondContact O-N 3.47Å; L122-K124 VanDerWaalsContact C-N 3.33Å; L122-K124 PolarHBondContact O-N 3.15Å
125	C	95.8	Very high	93	Very high	8 Å²	8	66.5 Å²	66.5	5%	0.054	38%	0.381	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-101.3	128.5	175.2	-60.1	0	0	0	0	109	D101 C111 C114 F118 Y119	D101-C125 HydrophobicContact CB-CB 3.89Å; D101-C125 PolarHBondContact O-SG 3.36Å; D101-C125 WeakPolarHBondContact OD2-CB 3.37Å; C111-C125 PolarHBondContact SG-SG 2.7Å; C114-C125 WeakPolarHBondContact CA-SG 3.32Å; C114-C125 HydrophobicContact CB-CB 3.77Å; C114-C125 WeakPolarHBondContact CB-SG 3.1Å; C114-C125 WeakPolarHBondContact SG-CA 3.42Å; C114-C125 WeakPolarHBondContact SG-CB 3.22Å; C114-C125 CovalentContact SG-SG 2.03Å; C114-C125 PolarHBondContact SG-SG 2.95Å; F118-C125 HydrophobicContact CB-CB 3.92Å; F118-C125 HydrophobicContact CD1-CB 4.4Å; F118-C125 HydrophobicContact CG-CB 4.37Å; Y119-C125 WeakPolarHBondContact O-CA 3.48Å
126	L	94.6	Very high	92.9	Very high	57 Å²	57	64.5 Å²	64.5	30%	0.298	38%	0.375	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-127.7	142.4	-176.3	-57.8	175.8	0	0	0	109.6	F118 Y119 H121 S128	F118-L126 CarbonylContact C-O 3.55Å; F118-L126 WeakPolarHBondContact CA-O 2.9Å; Y119-L126 PolarHBondContact N-O 3.37Å; Y119-L126 PolarHBondContact O-N 2.85Å; H121-L126 HydrophobicContact CB-CD1 4.02Å; L126-S128 VanDerWaalsContact C-N 3.27Å; L126-S128 PolarHBondContact O-N 3.42Å
127	D	93.6	Very high	92.7	Very high	114 Å²	114	65 Å²	65	61%	0.61	37%	0.37	S	S	*	.	S	Bend	trans	-66.5	-33	174.1	-63.8	-57.4	0	0	0	111.8	F118	F118-D127 WeakPolarHBondContact CD1-OD1 3.49Å; F118-D127 WeakPolarHBondContact CE1-OD1 3.35Å; F118-D127 WeakPolarHBondContact CZ-OD1 3.32Å
128	S	92.9	Very high	92.5	Very high	89 Å²	89	71.1 Å²	71.1	62%	0.622	38%	0.384	S	S	*	.	S	Bend	trans	-137.1	140	178.7	60	0	0	0	0	111.3	L126	L126-S128 VanDerWaalsContact C-N 3.27Å; L126-S128 PolarHBondContact O-N 3.42Å
129	C	93.8	Very high	92.2	Very high	26 Å²	26	72 Å²	72	18%	0.176	39%	0.394	C	S	.	.	P	Polyproline II helix	trans	-67.6	143.4	176.9	-64.9	0	0	0	0	112.1	L133 C142	C129-L133 HydrophobicContact CB-CB 4.17Å; C129-C142 WeakPolarHBondContact CA-SG 3.48Å; C129-C142 HydrophobicContact CB-CB 3.82Å; C129-C142 WeakPolarHBondContact CB-SG 3.36Å; C129-C142 WeakPolarHBondContact SG-CA 3.02Å; C129-C142 WeakPolarHBondContact SG-CB 3.37Å; C129-C142 CovalentContact SG-SG 2.05Å; C129-C142 PolarHBondContact SG-SG 3.32Å
130	P	93.1	Very high	92.1	Very high	54 Å²	54	73.5 Å²	73.5	35%	0.351	40%	0.403	S	S	.	.	P	Polyproline II helix	trans	-67.8	170.2	178.1	30.7	-36.2	0	0	0	111.9	L133	P130-L133 HydrophobicContact CG-CD1 3.74Å; P130-L133 HydrophobicContact CG-CG 4.41Å; P130-L133 PolarHBondContact O-N 3.45Å
131	E	88.6	Confident	92	Very high	200 Å²	200	75.9 Å²	75.9	94%	0.935	41%	0.413	S	S	*	.	T	Hydrogen-bonded Turn	trans	-56.3	140.6	179.8	-68.1	-175.2	178.5	0	0	112.4	L133	E131-L133 VanDerWaalsContact C-N 3.28Å; E131-L133 PolarHBondContact O-N 3.21Å
132	G	85.1	Confident	91.9	Very high	53 Å²	53	74.4 Å²	74.4	55%	0.546	41%	0.408	S	S	.	.	T	Hydrogen-bonded Turn	trans	83.1	-5	-176.8	0	0	0	0	0	115.2	I145	G132-I145 PolarHBondContact O-N 3.44Å
133	L	92.3	Very high	91.9	Very high	35 Å²	35	69.4 Å²	69.4	18%	0.183	38%	0.384	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-116.3	156.4	175.3	-56.3	179.9	0	0	0	111.5	H121 C129 P130 E131 C142 V143	H121-L133 WeakPolarHBondContact CE1-CD1 3.47Å; H121-L133 VanDerWaalsContact ND1-CD1 3.33Å; H121-L133 WeakPolarHBondContact ND1-CD1 3.49Å; C129-L133 HydrophobicContact CB-CB 4.17Å; P130-L133 HydrophobicContact CG-CD1 3.74Å; P130-L133 HydrophobicContact CG-CG 4.41Å; P130-L133 PolarHBondContact O-N 3.45Å; E131-L133 VanDerWaalsContact C-N 3.28Å; E131-L133 PolarHBondContact O-N 3.21Å; L133-C142 HydrophobicContact CB-CB 4.29Å; L133-C142 HydrophobicContact CD1-CB 3.9Å; L133-V143 CarbonylContact C-O 3.58Å; L133-V143 VanDerWaalsContact CA-O 3.28Å; L133-V143 WeakPolarHBondContact CA-O 3.45Å; L133-V143 WeakPolarHBondContact CB-O 3.11Å
134	E	92	Very high	91.8	Very high	23 Å²	23	72.7 Å²	72.7	11%	0.107	41%	0.406	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-119.7	155.3	171.6	63.2	168.8	-165.8	0	0	111.5	C142 V143 I145 S184 A185 K186	E134-C142 WeakPolarHBondContact O-CA 3.43Å; E134-V143 HydrophobicContact CG-CG2 3.64Å; E134-V143 PolarHBondContact N-O 3.26Å; E134-V143 PolarHBondContact O-N 3.39Å; E134-I145 HydrophobicContact CB-CG1 4.13Å; E134-I145 HydrophobicContact CG-CG1 4.27Å; E134-S184 VanDerWaalsContact CD-CB 3.45Å; E134-S184 WeakPolarHBondContact OE1-CB 3.24Å; E134-S184 WeakPolarHBondContact OE2-CB 3.4Å; E134-A185 PolarHBondContact OE2-N 3.46Å; E134-K186 HydrophobicContact CB-CB 4.48Å; E134-K186 HydrophobicContact CB-CD 3.95Å; E134-K186 HydrophobicContact CB-CG 4.23Å; E134-K186 PolarHBondContact OE2-N 3.31Å
135	A	92.6	Very high	91.7	Very high	39 Å²	39	68.9 Å²	68.9	32%	0.322	39%	0.391	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-83.8	119.4	179.2	0	0	0	0	0	109.9	Y119	Y119-A135 HydrophobicContact CD1-CB 3.86Å; Y119-A135 HydrophobicContact CD2-CB 4.43Å; Y119-A135 HydrophobicContact CE1-CB 3.5Å; Y119-A135 HydrophobicContact CE2-CB 4.1Å; Y119-A135 HydrophobicContact CG-CB 4.32Å
136	N	90.9	Very high	91.5	Very high	45 Å²	45	70.3 Å²	70.3	24%	0.241	40%	0.399	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-91.4	107.8	170.2	-173.7	-18.6	0	0	0	109.9	H138 T139 M140 E141 V143	N136-H138 PolarHBondContact O-N 3.38Å; N136-H138 WeakPolarHBondContact OD1-CB 3.02Å; N136-H138 PolarHBondContact OD1-N 3.5Å; N136-T139 PolarHBondContact ND2-OG1 3.02Å; N136-T139 PolarHBondContact O-N 3.02Å; N136-M140 VanDerWaalsContact O-CA 3.28Å; N136-M140 WeakPolarHBondContact O-CA 3.39Å; N136-M140 PolarHBondContact O-N 2.83Å; N136-E141 PolarHBondContact N-O 2.96Å; N136-V143 HydrophobicContact CB-CG1 4.08Å; N136-V143 HydrophobicContact CB-CG2 4.11Å
137	N	89.1	Confident	91.3	Very high	114 Å²	114	72 Å²	72	61%	0.61	41%	0.406	S	S	*	.	T	Hydrogen-bonded Turn	trans	-69.1	-18.2	-179	-68	-18.4	0	0	0	113.8	Y119	Y119-N137 PolarHBondContact OH-OD1 3.02Å
138	H	86.5	Confident	91.3	Very high	181 Å²	181	67.5 Å²	67.5	84%	0.838	38%	0.383	S	S	*	.	T	Hydrogen-bonded Turn	trans	-80.5	-39.2	179.2	-60.7	-66.1	0	0	0	112.2	N136	N136-H138 PolarHBondContact O-N 3.38Å; N136-H138 WeakPolarHBondContact OD1-CB 3.02Å; N136-H138 PolarHBondContact OD1-N 3.5Å
139	T	89.6	Confident	91.4	Very high	70 Å²	70	68.4 Å²	68.4	43%	0.429	38%	0.377	S	S	.	.	T	Hydrogen-bonded Turn	trans	-100.5	-13.5	-179.7	61.6	0	0	0	0	113.3	N136 E141	N136-T139 PolarHBondContact ND2-OG1 3.02Å; N136-T139 PolarHBondContact O-N 3.02Å; T139-E141 VanDerWaalsContact C-N 3.3Å; T139-E141 WeakPolarHBondContact CB-OE2 3.32Å; T139-E141 PolarHBondContact OG1-OE2 2.83Å
140	M	91.7	Very high	91.5	Very high	77 Å²	77	68.2 Å²	68.2	38%	0.379	38%	0.378	S	S	.	.	T	Hydrogen-bonded Turn	trans	56.1	44.8	-170	-60.9	-176.6	178	0	0	111.8	Y119 L120 N136	Y119-M140 CarbonylContact C-O 3.56Å; Y119-M140 WeakPolarHBondContact CA-O 3.47Å; L120-M140 PolarHBondContact N-O 3.19Å; N136-M140 VanDerWaalsContact O-CA 3.28Å; N136-M140 WeakPolarHBondContact O-CA 3.39Å; N136-M140 PolarHBondContact O-N 2.83Å
141	E	93.4	Very high	91.6	Very high	83 Å²	83	67 Å²	67	39%	0.388	37%	0.37	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-127.6	152.8	-179.3	-62.4	175.2	147	0	0	110.7	L120 N136 T139	L120-E141 HydrophobicContact CB-CG 4.21Å; N136-E141 PolarHBondContact N-O 2.96Å; T139-E141 VanDerWaalsContact C-N 3.3Å; T139-E141 WeakPolarHBondContact CB-OE2 3.32Å; T139-E141 PolarHBondContact OG1-OE2 2.83Å
142	C	94.2	Very high	92	Very high	16 Å²	16	64.8 Å²	64.8	11%	0.108	37%	0.365	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-85.6	113.6	169.5	-64	0	0	0	0	109.9	Y119 L120 H121 C129 L133 E134	Y119-C142 VanDerWaalsContact CB-SG 3.53Å; L120-C142 PolarHBondContact O-N 2.92Å; H121-C142 HydrophobicContact CB-CB 3.95Å; C129-C142 WeakPolarHBondContact CA-SG 3.48Å; C129-C142 HydrophobicContact CB-CB 3.82Å; C129-C142 WeakPolarHBondContact CB-SG 3.36Å; C129-C142 WeakPolarHBondContact SG-CA 3.02Å; C129-C142 WeakPolarHBondContact SG-CB 3.37Å; C129-C142 CovalentContact SG-SG 2.05Å; C129-C142 PolarHBondContact SG-SG 3.32Å; L133-C142 HydrophobicContact CB-CB 4.29Å; L133-C142 HydrophobicContact CD1-CB 3.9Å; E134-C142 WeakPolarHBondContact O-CA 3.43Å
143	V	92.8	Very high	92.6	Very high	41 Å²	41	65.7 Å²	65.7	25%	0.248	35%	0.352	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-108.7	154	-179.3	-60	0	0	0	0	110.7	L133 E134 N136	L133-V143 CarbonylContact C-O 3.58Å; L133-V143 VanDerWaalsContact CA-O 3.28Å; L133-V143 WeakPolarHBondContact CA-O 3.45Å; L133-V143 WeakPolarHBondContact CB-O 3.11Å; E134-V143 HydrophobicContact CG-CG2 3.64Å; E134-V143 PolarHBondContact N-O 3.26Å; E134-V143 PolarHBondContact O-N 3.39Å; N136-V143 HydrophobicContact CB-CG1 4.08Å; N136-V143 HydrophobicContact CB-CG2 4.11Å
144	S	91.1	Very high	92.8	Very high	75 Å²	75	65.2 Å²	65.2	52%	0.524	36%	0.356	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-66.4	138.9	176.9	54.9	0	0	0	0	111	V146	S144-V146 PolarHBondContact O-N 3.15Å; S144-V146 VanDerWaalsContact O-N 3.15Å
145	I	91.4	Very high	93	Very high	46 Å²	46	69.9 Å²	69.9	24%	0.236	39%	0.388	C	S	.	.	P	Polyproline II helix	trans	-64.2	118.2	171.3	-61.9	171.5	0	0	0	108.1	G132 E134 K186	G132-I145 PolarHBondContact O-N 3.44Å; E134-I145 HydrophobicContact CB-CG1 4.13Å; E134-I145 HydrophobicContact CG-CG1 4.27Å; I145-K186 HydrophobicContact CD1-CB 4.28Å; I145-K186 HydrophobicContact CG1-CB 4.36Å; I145-K186 HydrophobicContact CG2-CB 4.44Å
146	V	91.5	Very high	93.2	Very high	39 Å²	39	71 Å²	71	24%	0.236	38%	0.384	C	S	.	.	P	Polyproline II helix	trans	-95.5	122.3	175.2	178.2	0	0	0	0	108.4	S144 Q181 H182 P183 S184 G187	S144-V146 PolarHBondContact O-N 3.15Å; S144-V146 VanDerWaalsContact O-N 3.15Å; V146-Q181 HydrophobicContact CG1-CG 3.34Å; V146-H182 WeakPolarHBondContact CG1-O 3.04Å; V146-P183 WeakPolarHBondContact O-CA 3.29Å; V146-S184 PolarHBondContact N-OG 3.47Å; V146-S184 WeakPolarHBondContact O-CB 3.39Å; V146-S184 PolarHBondContact O-N 2.76Å; V146-S184 PolarHBondContact O-OG 2.82Å; V146-G187 WeakPolarHBondContact O-CA 3.49Å
147	H	90.5	Very high	93.4	Very high	92 Å²	92	70.7 Å²	70.7	43%	0.426	39%	0.385	S	S	.	.	P	Polyproline II helix	trans	-89.7	157.8	172.8	-59.4	-64.1	0	0	0	110.5	E149 N188	H147-E149 PolarHBondContact O-N 2.98Å; H147-N188 PolarHBondContact ND1-N 3.06Å; H147-N188 PolarHBondContact ND1-ND2 3.38Å
148	C	94.4	Very high	93.7	Very high	20 Å²	20	69.4 Å²	69.4	14%	0.135	38%	0.383	C	S	.	.	P	Polyproline II helix	trans	-71.6	127.3	176.7	-169.8	0	0	0	0	110.9	I179 Q181 P183 C190	C148-I179 WeakPolarHBondContact SG-CG2 3.44Å; C148-Q181 CarbonylContact C-O 3.55Å; C148-Q181 VanDerWaalsContact CA-O 3.26Å; C148-Q181 WeakPolarHBondContact CA-O 3Å; C148-Q181 PolarHBondContact SG-O 3.4Å; C148-P183 HydrophobicContact CB-CB 3.99Å; C148-P183 HydrophobicContact CB-CG 3.97Å; C148-C190 HydrophobicContact CB-CB 3.9Å; C148-C190 WeakPolarHBondContact CB-SG 3.47Å; C148-C190 WeakPolarHBondContact SG-CA 3.35Å; C148-C190 WeakPolarHBondContact SG-CB 3.39Å; C148-C190 CovalentContact SG-SG 2.04Å; C148-C190 PolarHBondContact SG-SG 2.83Å
149	E	94.6	Very high	94.1	Very high	108 Å²	108	61.4 Å²	61.4	51%	0.505	35%	0.347	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-114.4	126.3	174.7	-166.6	177.7	171.1	0	0	109.3	H147 L180 Q181	H147-E149 PolarHBondContact O-N 2.98Å; E149-L180 PolarHBondContact O-N 3.2Å; E149-Q181 HydrophobicContact CB-CB 3.79Å; E149-Q181 PolarHBondContact N-O 2.71Å; E149-Q181 PolarHBondContact O-N 3.33Å
150	A	96.1	Very high	94.3	Very high	22 Å²	22	61.3 Å²	61.3	18%	0.182	34%	0.343	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-105.3	147.2	176.5	0	0	0	0	0	109.7	E178 I179 P191	A150-E178 CarbonylContact C-O 3.58Å; A150-E178 WeakPolarHBondContact CA-O 3.46Å; A150-I179 HydrophobicContact CB-CD1 3.83Å; A150-P191 HydrophobicContact CB-CG 3.75Å
151	S	96.3	Very high	94.4	Very high	28 Å²	28	62.6 Å²	62.6	20%	0.196	35%	0.346	C	S	.	.	P	Polyproline II helix	trans	-62.4	167.3	175.3	76.4	0	0	0	0	111.4	E178	S151-E178 PolarHBondContact N-O 3.09Å; S151-E178 PolarHBondContact OG-N 3.09Å; S151-E178 PolarHBondContact OG-O 3.18Å
152	D	96.8	Very high	94.2	Very high	154 Å²	154	68.1 Å²	68.1	82%	0.824	37%	0.369	S	S	*	.	P	Polyproline II helix	trans	-55.5	151.3	161.3	-71	-36.8	0	0	0	110.7	G154	D152-G154 PolarHBondContact O-N 2.97Å
153	W	97.2	Very high	94	Very high	71 Å²	71	70.3 Å²	70.3	27%	0.269	39%	0.394	S	S	.	.	P	Polyproline II helix	trans	-65.1	132.6	176.5	-77.6	107.6	0	0	0	111.2	R175 R177 E195	W153-R175 VanDerWaalsContact CD1-CZ 3.42Å; W153-R175 HydrophobicContact CD2-CG 4.09Å; W153-R175 VanDerWaalsContact CD2-NE 3.34Å; W153-R175 HydrophobicContact CE3-CB 4.24Å; W153-R175 HydrophobicContact CE3-CG 3.51Å; W153-R175 HydrophobicContact CZ3-CG 3.88Å; W153-R177 HydrophobicContact CD2-CB 4.24Å; W153-R177 HydrophobicContact CD2-CG 4.24Å; W153-R177 HydrophobicContact CE3-CB 3.76Å; W153-R177 HydrophobicContact CE3-CG 3.8Å; W153-R177 HydrophobicContact CH2-CG 3.99Å; W153-R177 HydrophobicContact CZ2-CG 4.39Å; W153-R177 HydrophobicContact CZ3-CB 4.09Å; W153-R177 HydrophobicContact CZ3-CG 3.67Å; W153-E195 HydrophobicContact CH2-CB 3.61Å; W153-E195 HydrophobicContact CZ2-CB 4.12Å; W153-E195 HydrophobicContact CZ3-CB 3.99Å
154	G	96.4	Very high	93.8	Very high	26 Å²	26	74.8 Å²	74.8	27%	0.268	41%	0.411	S	S	.	.	P	Polyproline II helix	trans	-62.6	166.2	165	0	0	0	0	0	112.1	D152 V176	D152-G154 PolarHBondContact O-N 2.97Å; G154-V176 PolarHBondContact N-O 3.14Å
155	P	96.6	Very high	93.9	Very high	121 Å²	121	75.4 Å²	75.4	79%	0.786	41%	0.411	S	S	*	.	P	Polyproline II helix	trans	-60.9	150.6	175.2	27.5	-34.6	0	0	0	110.9	S157	P155-S157 PolarHBondContact O-N 3.25Å
156	W	96.4	Very high	93.8	Very high	63 Å²	63	74.8 Å²	74.8	24%	0.239	41%	0.411	C	S	.	.	P	Polyproline II helix	trans	-61.9	135	172.4	-71.6	99.1	0	0	0	110.6	E173 R175 E195 R197	W156-E173 HydrophobicContact CD2-CG 4.33Å; W156-E173 HydrophobicContact CE3-CB 4.23Å; W156-E173 HydrophobicContact CE3-CG 3.78Å; W156-E173 HydrophobicContact CZ3-CG 4.4Å; W156-R175 HydrophobicContact CD2-CB 4.02Å; W156-R175 HydrophobicContact CD2-CG 4.04Å; W156-R175 VanDerWaalsContact CE2-CD 3.48Å; W156-R175 HydrophobicContact CE3-CB 3.81Å; W156-R175 HydrophobicContact CE3-CG 3.81Å; W156-R175 HydrophobicContact CH2-CG 3.64Å; W156-R175 HydrophobicContact CZ2-CG 3.87Å; W156-R175 VanDerWaalsContact CZ2-NE 3.27Å; W156-R175 HydrophobicContact CZ3-CB 4.1Å; W156-R175 HydrophobicContact CZ3-CG 3.61Å; W156-E195 HydrophobicContact CH2-CB 4.34Å; W156-E195 HydrophobicContact CH2-CG 3.99Å; W156-E195 WeakPolarHBondContact CZ3-O 2.99Å; W156-R197 VanDerWaalsContact CE2-CZ 3.44Å; W156-R197 HydrophobicContact CE3-CG 4.06Å; W156-R197 HydrophobicContact CH2-CB 4.02Å; W156-R197 HydrophobicContact CH2-CG 3.64Å; W156-R197 HydrophobicContact CZ2-CG 4.15Å; W156-R197 HydrophobicContact CZ3-CB 4.19Å; W156-R197 HydrophobicContact CZ3-CG 3.58Å
157	S	95.2	Very high	93.8	Very high	37 Å²	37	75.1 Å²	75.1	26%	0.259	42%	0.422	S	S	.	.	P	Polyproline II helix	trans	-59.1	160.2	169.6	76.4	0	0	0	0	110.6	P155 C159 E173 T174	P155-S157 PolarHBondContact O-N 3.25Å; S157-C159 PolarHBondContact O-N 3.45Å; S157-E173 VanDerWaalsContact O-CB 3.27Å; S157-E173 WeakPolarHBondContact O-CB 3.49Å; S157-T174 WeakPolarHBondContact CB-O 3.19Å; S157-T174 PolarHBondContact N-O 2.82Å; S157-T174 PolarHBondContact OG-N 3.21Å; S157-T174 PolarHBondContact OG-O 3.45Å
158	P	94.5	Very high	93.9	Very high	87 Å²	87	71.3 Å²	71.3	57%	0.565	40%	0.404	S	S	*	.	P	Polyproline II helix	trans	-53.2	144.3	166.2	-24	34.2	0	0	0	111	M160 T165	P158-M160 WeakPolarHBondContact O-CG 3.36Å; P158-M160 PolarHBondContact O-N 3.03Å; P158-T165 HydrophobicContact CB-CG2 4.06Å
159	C	95.4	Very high	93.8	Very high	14 Å²	14	77 Å²	77	10%	0.095	43%	0.426	C	S	.	.	P	Polyproline II helix	trans	-58.4	126.1	171.8	-170.5	0	0	0	0	109.3	S157 F168 C199 V201	S157-C159 PolarHBondContact O-N 3.45Å; C159-F168 HydrophobicContact CB-CE2 4.49Å; C159-F168 VanDerWaalsContact O-CZ 3.32Å; C159-F168 WeakPolarHBondContact O-CZ 3.29Å; C159-C199 WeakPolarHBondContact CA-SG 3.39Å; C159-C199 HydrophobicContact CB-CB 3.83Å; C159-C199 WeakPolarHBondContact CB-SG 3.4Å; C159-C199 WeakPolarHBondContact SG-CB 3Å; C159-C199 CovalentContact SG-SG 2.01Å; C159-C199 PolarHBondContact SG-SG 3.49Å; C159-V201 HydrophobicContact CB-CG1 3.67Å
160	M	94.5	Very high	93.8	Very high	68 Å²	68	80.6 Å²	80.6	34%	0.335	44%	0.435	S	S	.	.	B	Isolated β-bridge	trans	-131.3	149	-175.3	-72.7	174.6	80	0	0	112.1	P158 K164 T165 G171 T172	P158-M160 WeakPolarHBondContact O-CG 3.36Å; P158-M160 PolarHBondContact O-N 3.03Å; M160-K164 CarbonylContact C-O 3.53Å; M160-K164 VanDerWaalsContact CA-O 3.24Å; M160-K164 WeakPolarHBondContact CA-O 3.49Å; M160-T165 HydrophobicContact CG-CG2 3.76Å; M160-G171 CarbonylContact O-C 3.57Å; M160-G171 VanDerWaalsContact O-CA 3.3Å; M160-G171 WeakPolarHBondContact O-CA 3.39Å; M160-T172 PolarHBondContact N-O 2.83Å; M160-T172 PolarHBondContact O-N 2.05Å
161	K	94.1	Very high	93.8	Very high	104 Å²	104	79.9 Å²	79.9	45%	0.452	43%	0.43	S	S	.	.	B	Isolated β-bridge	trans	-137.5	123.6	168.6	-167	-178.9	-165.4	162.7	0	109.6	G163 K164 F168 R170	K161-G163 VanDerWaalsContact C-N 3.26Å; K161-G163 PolarHBondContact O-N 3.49Å; K161-K164 PolarHBondContact N-O 3.05Å; K161-K164 PolarHBondContact O-N 3.29Å; K161-K164 VanDerWaalsContact O-N 3.12Å; K161-F168 HydrophobicContact CB-CB 4.06Å; K161-F168 HydrophobicContact CB-CD1 3.5Å; K161-F168 VanDerWaalsContact CB-CD1 3.5Å; K161-F168 HydrophobicContact CB-CD2 3.93Å; K161-F168 HydrophobicContact CB-CE1 3.92Å; K161-F168 HydrophobicContact CB-CE2 4.29Å; K161-F168 HydrophobicContact CB-CG 3.53Å; K161-F168 HydrophobicContact CB-CZ 4.3Å; K161-F168 HydrophobicContact CD-CB 3.61Å; K161-F168 HydrophobicContact CD-CG 4.04Å; K161-F168 HydrophobicContact CG-CB 4.47Å; K161-F168 HydrophobicContact CG-CG 4.42Å; K161-R170 WeakPolarHBondContact CD-O 3.25Å
162	K	88.7	Confident	93.8	Very high	199 Å²	199	81.7 Å²	81.7	87%	0.865	44%	0.44	S	S	*	.	T	Hydrogen-bonded Turn	trans	50.1	44.7	-176.8	-60.3	-175.9	176.6	-172.4	0	112.5	K164	K162-K164 VanDerWaalsContact C-N 3.29Å; K162-K164 PolarHBondContact O-N 3.29Å
163	G	89.5	Confident	93.8	Very high	62 Å²	62	75.6 Å²	75.6	64%	0.639	41%	0.406	S	S	*	.	T	Hydrogen-bonded Turn	trans	74.6	7.6	178.5	0	0	0	0	0	116	K161	K161-G163 VanDerWaalsContact C-N 3.26Å; K161-G163 PolarHBondContact O-N 3.49Å
164	K	89.7	Confident	93.7	Very high	135 Å²	135	74.6 Å²	74.6	59%	0.587	41%	0.408	S	S	*	.	B	Isolated β-bridge	trans	-117	152.2	-179.7	-62.1	178.9	-177	176.5	0	110.7	M160 K161 K162 F168	M160-K164 CarbonylContact C-O 3.53Å; M160-K164 VanDerWaalsContact CA-O 3.24Å; M160-K164 WeakPolarHBondContact CA-O 3.49Å; K161-K164 PolarHBondContact N-O 3.05Å; K161-K164 PolarHBondContact O-N 3.29Å; K161-K164 VanDerWaalsContact O-N 3.12Å; K162-K164 VanDerWaalsContact C-N 3.29Å; K162-K164 PolarHBondContact O-N 3.29Å; K164-F168 WeakPolarHBondContact O-CE1 3.47Å
165	T	92.6	Very high	93.8	Very high	87 Å²	87	76 Å²	76	53%	0.534	41%	0.405	S	S	.	.	S	Bend	trans	-103.2	3.1	177	53.2	0	0	0	0	113.6	P158 M160 F168	P158-T165 HydrophobicContact CB-CG2 4.06Å; M160-T165 HydrophobicContact CG-CG2 3.76Å; T165-F168 VanDerWaalsContact C-CE1 3.43Å
166	C	89.7	Confident	93.8	Very high	34 Å²	34	74.7 Å²	74.7	23%	0.23	40%	0.395	C	S	.	.	S	Bend	trans	-134.2	164	-177.2	59.2	0	0	0	0	111.6	F168 C206	C166-F168 VanDerWaalsContact O-CD1 3.26Å; C166-F168 WeakPolarHBondContact O-CD1 3.41Å; C166-C206 HydrophobicContact CB-CB 4.03Å; C166-C206 WeakPolarHBondContact CB-SG 3.46Å; C166-C206 PolarHBondContact O-SG 3.15Å; C166-C206 WeakPolarHBondContact SG-CA 3.18Å; C166-C206 WeakPolarHBondContact SG-CB 3.37Å; C166-C206 CovalentContact SG-SG 2.03Å; C166-C206 PolarHBondContact SG-SG 3.36Å
167	G	90.4	Very high	93.8	Very high	45 Å²	45	73.9 Å²	73.9	46%	0.464	39%	0.392	S	S	.	.	S	Bend	trans	81.6	8.4	173	0	0	0	0	0	116.1	K204	G167-K204 WeakPolarHBondContact CA-O 3.05Å; G167-K204 PolarHBondContact N-O 3.35Å
168	F	93.2	Very high	93.9	Very high	13 Å²	13	79.2 Å²	79.2	6%	0.057	41%	0.413	C	S	.	.			trans	-133.2	162.6	176.3	60	-88	0	0	0	111.9	C159 K161 K164 T165 C166 R170 V201	C159-F168 HydrophobicContact CB-CE2 4.49Å; C159-F168 VanDerWaalsContact O-CZ 3.32Å; C159-F168 WeakPolarHBondContact O-CZ 3.29Å; K161-F168 HydrophobicContact CB-CB 4.06Å; K161-F168 HydrophobicContact CB-CD1 3.5Å; K161-F168 VanDerWaalsContact CB-CD1 3.5Å; K161-F168 HydrophobicContact CB-CD2 3.93Å; K161-F168 HydrophobicContact CB-CE1 3.92Å; K161-F168 HydrophobicContact CB-CE2 4.29Å; K161-F168 HydrophobicContact CB-CG 3.53Å; K161-F168 HydrophobicContact CB-CZ 4.3Å; K161-F168 HydrophobicContact CD-CB 3.61Å; K161-F168 HydrophobicContact CD-CG 4.04Å; K161-F168 HydrophobicContact CG-CB 4.47Å; K161-F168 HydrophobicContact CG-CG 4.42Å; K164-F168 WeakPolarHBondContact O-CE1 3.47Å; T165-F168 VanDerWaalsContact C-CE1 3.43Å; C166-F168 VanDerWaalsContact O-CD1 3.26Å; C166-F168 WeakPolarHBondContact O-CD1 3.41Å; F168-R170 WeakPolarHBondContact CD2-O 3.03Å; F168-V201 HydrophobicContact CD2-CG2 3.9Å; F168-V201 HydrophobicContact CE2-CG2 3.48Å; F168-V201 VanDerWaalsContact CE2-CG2 3.48Å; F168-V201 HydrophobicContact CZ-CG2 4.18Å
169	K	92.8	Very high	94	Very high	139 Å²	139	76.8 Å²	76.8	60%	0.604	40%	0.395	S	S	*	.	S	Bend	trans	-103	-33.9	174	-172.8	176.8	-178.3	179.3	0	112.7	I200 V201	K169-I200 HydrophobicContact CG-CG2 4.3Å; K169-I200 CarbonylContact O-C 3.51Å; K169-I200 VanDerWaalsContact O-CA 3.27Å; K169-I200 WeakPolarHBondContact O-CA 3.13Å; K169-V201 WeakPolarHBondContact CA-O 2.98Å; K169-V201 PolarHBondContact O-N 2.83Å
170	R	94.8	Very high	94	Very high	184 Å²	184	81.4 Å²	81.4	69%	0.694	42%	0.418	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-119.1	127.7	176.8	-63.9	-176.2	-178.5	168.7	0.6	109.4	K161 F168 C199 I200	K161-R170 WeakPolarHBondContact CD-O 3.25Å; F168-R170 WeakPolarHBondContact CD2-O 3.03Å; R170-C199 WeakPolarHBondContact CA-O 3.41Å; R170-I200 HydrophobicContact CG-CG1 4.35Å
171	G	95.1	Very high	93.9	Very high	7 Å²	7	82.3 Å²	82.3	7%	0.072	42%	0.421	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-137.6	-166.4	176.5	0	0	0	0	0	111.1	M160 T198 C199	M160-G171 CarbonylContact O-C 3.57Å; M160-G171 VanDerWaalsContact O-CA 3.3Å; M160-G171 WeakPolarHBondContact O-CA 3.39Å; G171-T198 WeakPolarHBondContact O-CA 3.31Å; G171-C199 PolarHBondContact N-O 3.07Å; G171-C199 PolarHBondContact O-N 3.02Å; G171-C199 PolarHBondContact O-SG 2.9Å; G171-C199 VanDerWaalsContact O-SG 3.41Å
172	T	96.9	Very high	93.9	Very high	65 Å²	65	83.8 Å²	83.8	40%	0.399	43%	0.43	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-128.9	143.6	174.1	51.3	0	0	0	0	109.6	M160 T196 R197 C199	M160-T172 PolarHBondContact N-O 2.83Å; M160-T172 PolarHBondContact O-N 2.05Å; T172-T196 HydrophobicContact CG2-CG2 4.27Å; T172-R197 CarbonylContact C-O 3.55Å; T172-R197 VanDerWaalsContact CA-O 3.26Å; T172-R197 WeakPolarHBondContact CA-O 2.98Å; T172-C199 PolarHBondContact N-SG 2.97Å; T172-C199 VanDerWaalsContact N-SG 3.42Å
173	E	96.1	Very high	94.1	Very high	26 Å²	26	76.5 Å²	76.5	12%	0.121	40%	0.403	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-121.4	146	169.5	53.2	-166.9	-152.5	0	0	108.7	W156 S157 T196 R197 C199	W156-E173 HydrophobicContact CD2-CG 4.33Å; W156-E173 HydrophobicContact CE3-CB 4.23Å; W156-E173 HydrophobicContact CE3-CG 3.78Å; W156-E173 HydrophobicContact CZ3-CG 4.4Å; S157-E173 VanDerWaalsContact O-CB 3.27Å; S157-E173 WeakPolarHBondContact O-CB 3.49Å; E173-T196 WeakPolarHBondContact O-CA 3.46Å; E173-R197 HydrophobicContact CG-CG 3.68Å; E173-R197 PolarHBondContact N-O 2.03Å; E173-R197 PolarHBondContact O-N 2.04Å; E173-R197 IonicContact OE1-CZ 2.65Å; E173-R197 IonicContact OE1-NE 3.07Å; E173-R197 PolarHBondContact OE1-NE 2.74Å; E173-R197 IonicContact OE1-NH2 2.64Å; E173-R197 PolarHBondContact OE1-NH2 3.46Å; E173-C199 HydrophobicContact CG-CB 4.09Å
174	T	96.3	Very high	94.1	Very high	50 Å²	50	74.7 Å²	74.7	31%	0.307	38%	0.38	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-124.8	138.7	-177.5	-57.9	0	0	0	0	108.4	S157 E195 T196	S157-T174 WeakPolarHBondContact CB-O 3.19Å; S157-T174 PolarHBondContact N-O 2.82Å; S157-T174 PolarHBondContact OG-N 3.21Å; S157-T174 PolarHBondContact OG-O 3.45Å; T174-E195 CarbonylContact C-O 3.58Å; T174-E195 VanDerWaalsContact CA-O 3.25Å; T174-E195 WeakPolarHBondContact CA-O 3.41Å; T174-E195 WeakPolarHBondContact CG2-O 3.43Å; T174-T196 PolarHBondContact OG1-OG1 3.04Å; T174-T196 VanDerWaalsContact OG1-OG1 3.05Å
175	R	97.1	Very high	93.9	Very high	55 Å²	55	73.1 Å²	73.1	21%	0.208	39%	0.393	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-117.2	152.7	167.1	62.5	176.5	-177.9	175.8	-0.9	109.1	W153 W156 S194 E195	W153-R175 VanDerWaalsContact CD1-CZ 3.42Å; W153-R175 HydrophobicContact CD2-CG 4.09Å; W153-R175 VanDerWaalsContact CD2-NE 3.34Å; W153-R175 HydrophobicContact CE3-CB 4.24Å; W153-R175 HydrophobicContact CE3-CG 3.51Å; W153-R175 HydrophobicContact CZ3-CG 3.88Å; W156-R175 HydrophobicContact CD2-CB 4.02Å; W156-R175 HydrophobicContact CD2-CG 4.04Å; W156-R175 VanDerWaalsContact CE2-CD 3.48Å; W156-R175 HydrophobicContact CE3-CB 3.81Å; W156-R175 HydrophobicContact CE3-CG 3.81Å; W156-R175 HydrophobicContact CH2-CG 3.64Å; W156-R175 HydrophobicContact CZ2-CG 3.87Å; W156-R175 VanDerWaalsContact CZ2-NE 3.27Å; W156-R175 HydrophobicContact CZ3-CB 4.1Å; W156-R175 HydrophobicContact CZ3-CG 3.61Å; R175-S194 WeakPolarHBondContact O-CA 3.29Å; R175-E195 HydrophobicContact CG-CB 4.03Å; R175-E195 IonicContact CZ-OE2 3.98Å; R175-E195 PolarHBondContact N-O 2.91Å; R175-E195 IonicContact NE-OE2 3.09Å; R175-E195 PolarHBondContact NE-OE2 2.8Å; R175-E195 IonicContact NH2-OE1 2.83Å; R175-E195 IonicContact NH2-OE2 2.75Å; R175-E195 PolarHBondContact NH2-OE2 3.29Å; R175-E195 PolarHBondContact O-N 3.33Å
176	V	97.1	Very high	93.6	Very high	95 Å²	95	75.5 Å²	75.5	58%	0.576	40%	0.395	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-125.8	153.1	179.1	-64.4	0	0	0	0	109.6	G154 T193	G154-V176 PolarHBondContact N-O 3.14Å; V176-T193 CarbonylContact C-O 3.56Å; V176-T193 VanDerWaalsContact CA-O 3.28Å; V176-T193 WeakPolarHBondContact CA-O 3.39Å
177	R	96.9	Very high	93.5	Very high	46 Å²	46	74.8 Å²	74.8	17%	0.174	39%	0.394	C	S	.	.			trans	-139.5	160.4	170.4	66.1	177.7	173.8	174.3	-9.1	109.2	W153 P192 T193	W153-R177 HydrophobicContact CD2-CB 4.24Å; W153-R177 HydrophobicContact CD2-CG 4.24Å; W153-R177 HydrophobicContact CE3-CB 3.76Å; W153-R177 HydrophobicContact CE3-CG 3.8Å; W153-R177 HydrophobicContact CH2-CG 3.99Å; W153-R177 HydrophobicContact CZ2-CG 4.39Å; W153-R177 HydrophobicContact CZ3-CB 4.09Å; W153-R177 HydrophobicContact CZ3-CG 3.67Å; R177-P192 VanDerWaalsContact CZ-O 3.25Å; R177-P192 PolarHBondContact NE-O 3.45Å; R177-P192 PolarHBondContact NH2-O 3.49Å; R177-T193 PolarHBondContact N-O 3.47Å; R177-T193 WeakPolarHBondContact O-CB 2.97Å
178	E	96	Very high	93.4	Very high	149 Å²	149	77.5 Å²	77.5	70%	0.696	40%	0.398	S	S	*	.			trans	-106.2	157.4	-177.5	-62.5	-176.6	169.2	0	0	110.5	A150 S151	A150-E178 CarbonylContact C-O 3.58Å; A150-E178 WeakPolarHBondContact CA-O 3.46Å; S151-E178 PolarHBondContact N-O 3.09Å; S151-E178 PolarHBondContact OG-N 3.09Å; S151-E178 PolarHBondContact OG-O 3.18Å
179	I	96.9	Very high	93.3	Very high	35 Å²	35	84.8 Å²	84.8	18%	0.179	44%	0.436	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-90	114	172	-59.6	-53.3	0	0	0	107.6	C148 A150 Q181 C190 T193	C148-I179 WeakPolarHBondContact SG-CG2 3.44Å; A150-I179 HydrophobicContact CB-CD1 3.83Å; I179-Q181 VanDerWaalsContact CG2-O 3.25Å; I179-Q181 WeakPolarHBondContact CG2-O 3.32Å; I179-C190 HydrophobicContact CD1-CB 3.98Å; I179-C190 HydrophobicContact CG1-CB 4.42Å; I179-T193 HydrophobicContact CD1-CG2 3.75Å; I179-T193 HydrophobicContact CG1-CG2 3.77Å
180	L	94.9	Very high	93.3	Very high	112 Å²	112	80.6 Å²	80.6	59%	0.586	42%	0.424	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-79.8	-40.1	178.8	-62.5	179.9	0	0	0	110.9	E149	E149-L180 PolarHBondContact O-N 3.2Å
181	Q	94.1	Very high	93.3	Very high	87 Å²	87	74 Å²	74	41%	0.407	41%	0.405	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-129.3	123.7	179.8	-173.5	159.4	57.9	0	0	109.9	V146 C148 E149 I179	V146-Q181 HydrophobicContact CG1-CG 3.34Å; C148-Q181 CarbonylContact C-O 3.55Å; C148-Q181 VanDerWaalsContact CA-O 3.26Å; C148-Q181 WeakPolarHBondContact CA-O 3Å; C148-Q181 PolarHBondContact SG-O 3.4Å; E149-Q181 HydrophobicContact CB-CB 3.79Å; E149-Q181 PolarHBondContact N-O 2.71Å; E149-Q181 PolarHBondContact O-N 3.33Å; I179-Q181 VanDerWaalsContact CG2-O 3.25Å; I179-Q181 WeakPolarHBondContact CG2-O 3.32Å
182	H	92.3	Very high	93.3	Very high	135 Å²	135	78 Å²	78	63%	0.625	43%	0.429	S	S	*	.	P	Polyproline II helix	trans	-81	145.7	174.6	-71.1	79.3	0	0	0	110.1	V146	V146-H182 WeakPolarHBondContact CG1-O 3.04Å
183	P	93	Very high	93.3	Very high	46 Å²	46	78.1 Å²	78.1	30%	0.299	43%	0.43	S	S	.	.	P	Polyproline II helix	trans	-73.7	148.3	-178.5	29.9	-31.7	0	0	0	110.4	V146 C148 N188 C190	V146-P183 WeakPolarHBondContact O-CA 3.29Å; C148-P183 HydrophobicContact CB-CB 3.99Å; C148-P183 HydrophobicContact CB-CG 3.97Å; P183-N188 VanDerWaalsContact CB-O 3.23Å; P183-N188 WeakPolarHBondContact CB-O 3.38Å; P183-C190 WeakPolarHBondContact CD-SG 3.19Å
184	S	90.3	Very high	93.3	Very high	23 Å²	23	80.2 Å²	80.2	16%	0.161	45%	0.448	C	S	.	.	P	Polyproline II helix	trans	-64.6	173.5	162.3	52.9	0	0	0	0	112.8	E134 V146 K186 G187	E134-S184 VanDerWaalsContact CD-CB 3.45Å; E134-S184 WeakPolarHBondContact OE1-CB 3.24Å; E134-S184 WeakPolarHBondContact OE2-CB 3.4Å; V146-S184 PolarHBondContact N-OG 3.47Å; V146-S184 WeakPolarHBondContact O-CB 3.39Å; V146-S184 PolarHBondContact O-N 2.76Å; V146-S184 PolarHBondContact O-OG 2.82Å; S184-K186 VanDerWaalsContact C-N 3.25Å; S184-K186 PolarHBondContact O-N 2.03Å; S184-G187 PolarHBondContact O-N 3.15Å; S184-G187 WeakPolarHBondContact OG-CA 3.3Å; S184-G187 PolarHBondContact OG-N 2.92Å; S184-G187 VanDerWaalsContact OG-N 3.15Å
185	A	85.4	Confident	93.3	Very high	103 Å²	103	81.3 Å²	81.3	85%	0.851	45%	0.45	S	S	*	.	T	Hydrogen-bonded Turn	trans	-59	-36.8	177.8	0	0	0	0	0	112.5	E134	E134-A185 PolarHBondContact OE2-N 3.46Å
186	K	85.6	Confident	93.3	Very high	136 Å²	136	82.7 Å²	82.7	59%	0.591	46%	0.464	S	S	*	.	T	Hydrogen-bonded Turn	trans	-96.3	8.9	173.2	-62.7	-170.6	-175.7	179	0	113.8	E134 I145 S184	E134-K186 HydrophobicContact CB-CB 4.48Å; E134-K186 HydrophobicContact CB-CD 3.95Å; E134-K186 HydrophobicContact CB-CG 4.23Å; E134-K186 PolarHBondContact OE2-N 3.31Å; I145-K186 HydrophobicContact CD1-CB 4.28Å; I145-K186 HydrophobicContact CG1-CB 4.36Å; I145-K186 HydrophobicContact CG2-CB 4.44Å; S184-K186 VanDerWaalsContact C-N 3.25Å; S184-K186 PolarHBondContact O-N 2.03Å
187	G	87.6	Confident	93.2	Very high	19 Å²	19	83.7 Å²	83.7	20%	0.196	46%	0.458	C	S	.	.	S	Bend	trans	-72.9	166.5	179.9	0	0	0	0	0	113.2	V146 S184	V146-G187 WeakPolarHBondContact O-CA 3.49Å; S184-G187 PolarHBondContact O-N 3.15Å; S184-G187 WeakPolarHBondContact OG-CA 3.3Å; S184-G187 PolarHBondContact OG-N 2.92Å; S184-G187 VanDerWaalsContact OG-N 3.15Å
188	N	89.1	Confident	93.2	Very high	103 Å²	103	87.3 Å²	87.3	55%	0.551	49%	0.485	S	S	*	.	P	Polyproline II helix	trans	-75.3	145.5	174.1	-69.1	-32.8	0	0	0	109.9	H147 P183	H147-N188 PolarHBondContact ND1-N 3.06Å; H147-N188 PolarHBondContact ND1-ND2 3.38Å; P183-N188 VanDerWaalsContact CB-O 3.23Å; P183-N188 WeakPolarHBondContact CB-O 3.38Å
189	L	90.9	Very high	93.1	Very high	165 Å²	165	80.8 Å²	80.8	86%	0.864	46%	0.455	S	S	*	.	P	Polyproline II helix	trans	-57.8	144.2	175.1	-66.3	176.8	0	0	0	111.1
190	C	93.7	Very high	93	Very high	51 Å²	51	85.1 Å²	85.1	35%	0.345	48%	0.478	S	S	.	.	P	Polyproline II helix	trans	-63.6	136.2	177.2	-71.4	0	0	0	0	111.6	C148 I179 P183	C148-C190 HydrophobicContact CB-CB 3.9Å; C148-C190 WeakPolarHBondContact CB-SG 3.47Å; C148-C190 WeakPolarHBondContact SG-CA 3.35Å; C148-C190 WeakPolarHBondContact SG-CB 3.39Å; C148-C190 CovalentContact SG-SG 2.04Å; C148-C190 PolarHBondContact SG-SG 2.83Å; I179-C190 HydrophobicContact CD1-CB 3.98Å; I179-C190 HydrophobicContact CG1-CB 4.42Å; P183-C190 WeakPolarHBondContact CD-SG 3.19Å
191	P	94	Very high	93	Very high	46 Å²	46	82.1 Å²	82.1	30%	0.299	46%	0.464	S	S	.	.	P	Polyproline II helix	trans	-72.6	162	175.9	39.3	-40.8	0	0	0	109.1	A150	A150-P191 HydrophobicContact CB-CG 3.75Å
192	P	94.9	Very high	92.8	Very high	90 Å²	90	85.6 Å²	85.6	58%	0.584	48%	0.48	S	S	*	.	P	Polyproline II helix	trans	-63.5	139.4	-172.2	23.8	-34.2	0	0	0	112.2	R177	R177-P192 VanDerWaalsContact CZ-O 3.25Å; R177-P192 PolarHBondContact NE-O 3.45Å; R177-P192 PolarHBondContact NH2-O 3.49Å
193	T	96.4	Very high	92.6	Very high	68 Å²	68	88.4 Å²	88.4	42%	0.417	49%	0.485	S	S	.	.	S	Bend	trans	-89.6	-12	-177.5	50.9	0	0	0	0	114	V176 R177 I179	V176-T193 CarbonylContact C-O 3.56Å; V176-T193 VanDerWaalsContact CA-O 3.28Å; V176-T193 WeakPolarHBondContact CA-O 3.39Å; R177-T193 PolarHBondContact N-O 3.47Å; R177-T193 WeakPolarHBondContact O-CB 2.97Å; I179-T193 HydrophobicContact CD1-CG2 3.75Å; I179-T193 HydrophobicContact CG1-CG2 3.77Å
194	S	96.1	Very high	92.4	Very high	70 Å²	70	93.7 Å²	93.7	49%	0.49	50%	0.504	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-131	135.6	177.8	64.5	0	0	0	0	111	R175	R175-S194 WeakPolarHBondContact O-CA 3.29Å
195	E	97.3	Very high	92.1	Very high	74 Å²	74	102.4 Å²	102.4	35%	0.346	54%	0.539	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-128.1	132.9	173.2	-172.7	-176.2	-179.9	0	0	109.7	W153 W156 T174 R175	W153-E195 HydrophobicContact CH2-CB 3.61Å; W153-E195 HydrophobicContact CZ2-CB 4.12Å; W153-E195 HydrophobicContact CZ3-CB 3.99Å; W156-E195 HydrophobicContact CH2-CB 4.34Å; W156-E195 HydrophobicContact CH2-CG 3.99Å; W156-E195 WeakPolarHBondContact CZ3-O 2.99Å; T174-E195 CarbonylContact C-O 3.58Å; T174-E195 VanDerWaalsContact CA-O 3.25Å; T174-E195 WeakPolarHBondContact CA-O 3.41Å; T174-E195 WeakPolarHBondContact CG2-O 3.43Å; R175-E195 HydrophobicContact CG-CB 4.03Å; R175-E195 IonicContact CZ-OE2 3.98Å; R175-E195 PolarHBondContact N-O 2.91Å; R175-E195 IonicContact NE-OE2 3.09Å; R175-E195 PolarHBondContact NE-OE2 2.8Å; R175-E195 IonicContact NH2-OE1 2.83Å; R175-E195 IonicContact NH2-OE2 2.75Å; R175-E195 PolarHBondContact NH2-OE2 3.29Å; R175-E195 PolarHBondContact O-N 3.33Å
196	T	96.4	Very high	92.1	Very high	83 Å²	83	100 Å²	100	51%	0.509	52%	0.515	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-119.4	132	178.9	-57.1	0	0	0	0	109.5	T172 E173 T174	T172-T196 HydrophobicContact CG2-CG2 4.27Å; E173-T196 WeakPolarHBondContact O-CA 3.46Å; T174-T196 PolarHBondContact OG1-OG1 3.04Å; T174-T196 VanDerWaalsContact OG1-OG1 3.05Å
197	R	96.1	Very high	91.8	Very high	117 Å²	117	98.9 Å²	98.9	44%	0.442	53%	0.525	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-128.7	158	174.3	74.1	-179.7	-176.8	-177.9	2.8	112	W156 T172 E173	W156-R197 VanDerWaalsContact CE2-CZ 3.44Å; W156-R197 HydrophobicContact CE3-CG 4.06Å; W156-R197 HydrophobicContact CH2-CB 4.02Å; W156-R197 HydrophobicContact CH2-CG 3.64Å; W156-R197 HydrophobicContact CZ2-CG 4.15Å; W156-R197 HydrophobicContact CZ3-CB 4.19Å; W156-R197 HydrophobicContact CZ3-CG 3.58Å; T172-R197 CarbonylContact C-O 3.55Å; T172-R197 VanDerWaalsContact CA-O 3.26Å; T172-R197 WeakPolarHBondContact CA-O 2.98Å; E173-R197 HydrophobicContact CG-CG 3.68Å; E173-R197 PolarHBondContact N-O 2.03Å; E173-R197 PolarHBondContact O-N 2.04Å; E173-R197 IonicContact OE1-CZ 2.65Å; E173-R197 IonicContact OE1-NE 3.07Å; E173-R197 PolarHBondContact OE1-NE 2.74Å; E173-R197 IonicContact OE1-NH2 2.64Å; E173-R197 PolarHBondContact OE1-NH2 3.46Å
198	T	96.6	Very high	90.9	Very high	121 Å²	121	108 Å²	108	74%	0.742	56%	0.559	S	S	*	*	E	Extended strand (participates in β ladder)	trans	-79.6	141.4	174	56.8	0	0	0	0	111.1	G171	G171-T198 WeakPolarHBondContact O-CA 3.31Å
199	C	94.4	Very high	89.4	Confident	12 Å²	12	105.7 Å²	105.7	8%	0.081	56%	0.559	C	S	.	*	E	Extended strand (participates in β ladder)	trans	-130.8	150.2	-180	48	0	0	0	0	110.9	C159 R170 G171 T172 E173	C159-C199 WeakPolarHBondContact CA-SG 3.39Å; C159-C199 HydrophobicContact CB-CB 3.83Å; C159-C199 WeakPolarHBondContact CB-SG 3.4Å; C159-C199 WeakPolarHBondContact SG-CB 3Å; C159-C199 CovalentContact SG-SG 2.01Å; C159-C199 PolarHBondContact SG-SG 3.49Å; R170-C199 WeakPolarHBondContact CA-O 3.41Å; G171-C199 PolarHBondContact N-O 3.07Å; G171-C199 PolarHBondContact O-N 3.02Å; G171-C199 PolarHBondContact O-SG 2.9Å; G171-C199 VanDerWaalsContact O-SG 3.41Å; T172-C199 PolarHBondContact N-SG 2.97Å; T172-C199 VanDerWaalsContact N-SG 3.42Å; E173-C199 HydrophobicContact CG-CB 4.09Å
200	I	94.9	Very high	87.4	Confident	126 Å²	126	106.2 Å²	106.2	65%	0.646	56%	0.557	S	S	*	*	E	Extended strand (participates in β ladder)	trans	-119	123.7	178.6	-57.8	177	0	0	0	108.2	K169 R170	K169-I200 HydrophobicContact CG-CG2 4.3Å; K169-I200 CarbonylContact O-C 3.51Å; K169-I200 VanDerWaalsContact O-CA 3.27Å; K169-I200 WeakPolarHBondContact O-CA 3.13Å; R170-I200 HydrophobicContact CG-CG1 4.35Å
201	V	93.3	Very high	85.3	Confident	49 Å²	49	115.2 Å²	115.2	30%	0.297	58%	0.584	S	S	.	*			trans	-128.8	157.9	-179.1	-64.5	0	0	0	0	111.1	C159 F168 K169	C159-V201 HydrophobicContact CB-CG1 3.67Å; F168-V201 HydrophobicContact CD2-CG2 3.9Å; F168-V201 HydrophobicContact CE2-CG2 3.48Å; F168-V201 VanDerWaalsContact CE2-CG2 3.48Å; F168-V201 HydrophobicContact CZ-CG2 4.18Å; K169-V201 WeakPolarHBondContact CA-O 2.98Å; K169-V201 PolarHBondContact O-N 2.83Å
202	Q	90.3	Very high	83.1	Confident	161 Å²	161	115.5 Å²	115.5	75%	0.752	60%	0.595	S	S	*	*			trans	-68.3	134.8	171.4	-65.9	-63.1	-9.7	0	0	110.4	K204	Q202-K204 PolarHBondContact O-N 3.49Å
203	R	88.8	Confident	80.8	Confident	193 Å²	193	119.1 Å²	119.1	73%	0.728	60%	0.602	S	S	*	*			trans	-72.7	88.5	-175.2	-166.4	174.5	82.8	168.2	2.9	110.8
204	K	87.4	Confident	78.3	Confident	157 Å²	157	124.2 Å²	124.2	68%	0.683	62%	0.618	S	S	*	*	P	Polyproline II helix	trans	-75.1	138.8	172.8	-64.9	-179	-177.7	-178.8	0	110.7	G167 Q202 C206	G167-K204 WeakPolarHBondContact CA-O 3.05Å; G167-K204 PolarHBondContact N-O 3.35Å; Q202-K204 PolarHBondContact O-N 3.49Å; K204-C206 PolarHBondContact O-N 2.9Å
205	K	84.4	Confident	76	Confident	206 Å²	206	123.1 Å²	123.1	90%	0.896	62%	0.618	S	S	*	*	P	Polyproline II helix	trans	-65.3	127.9	170.5	-75.3	-177.5	-179.5	175.8	0	108.4	S207	K205-S207 PolarHBondContact O-N 2.89Å
206	C	85.3	Confident	73.8	Confident	54 Å²	54	129.6 Å²	129.6	37%	0.365	64%	0.639	S	S	.	*	P	Polyproline II helix	trans	-66.2	122.2	171.7	-68.2	0	0	0	0	109.2	C166 K204 K208	C166-C206 HydrophobicContact CB-CB 4.03Å; C166-C206 WeakPolarHBondContact CB-SG 3.46Å; C166-C206 PolarHBondContact O-SG 3.15Å; C166-C206 WeakPolarHBondContact SG-CA 3.18Å; C166-C206 WeakPolarHBondContact SG-CB 3.37Å; C166-C206 CovalentContact SG-SG 2.03Å; C166-C206 PolarHBondContact SG-SG 3.36Å; K204-C206 PolarHBondContact O-N 2.9Å; C206-K208 PolarHBondContact O-N 2.84Å
207	S	79.1	Confident	71.7	Confident	112 Å²	112	130.5 Å²	130.5	78%	0.783	64%	0.638	S	S	*	*	P	Polyproline II helix	trans	-59.8	122.5	164	47.7	0	0	0	0	107.2	K205 G209	K205-S207 PolarHBondContact O-N 2.89Å; S207-G209 VanDerWaalsContact C-N 3.28Å; S207-G209 PolarHBondContact O-N 3.38Å
208	K	70.3	Confident	69.7	Low	210 Å²	210	134.7 Å²	134.7	91%	0.913	65%	0.653	S	S	*	*			trans	-64.1	97.7	169.8	-77.2	-177.5	178.4	175.4	0	106.1	C206	C206-K208 PolarHBondContact O-N 2.84Å
209	G	56.4	Low	67.7	Low	54 Å²	54	136 Å²	136	56%	0.557	65%	0.649	S	S	*	*			trans	-50.4	148	165.8	0	0	0	0	0	109.2	S207 R211	S207-G209 VanDerWaalsContact C-N 3.28Å; S207-G209 PolarHBondContact O-N 3.38Å; G209-R211 PolarHBondContact O-N 2.81Å
210	E	50.4	Low	65.9	Low	177 Å²	177	144.6 Å²	144.6	83%	0.827	68%	0.68	S	S	*	*	S	Bend	trans	-60.4	31.9	-170.6	-59.3	-177.6	116	0	0	116.1	G212	E210-G212 PolarHBondContact O-N 3.19Å
211	R	48.9	Very low	64.1	Low	240 Å²	240	145.1 Å²	145.1	91%	0.906	68%	0.677	S	S	*	*	T	Hydrogen-bonded Turn	trans	-75.4	5.9	170.1	-68.6	-174.5	177.2	-177.8	-0.4	113.4	G209	G209-R211 PolarHBondContact O-N 2.81Å
212	G	46.5	Very low	62.4	Low	52 Å²	52	149.5 Å²	149.5	54%	0.536	69%	0.692	S	S	.	*	T	Hydrogen-bonded Turn	trans	-86.4	-20.3	179	0	0	0	0	0	115.7	E210	E210-G212 PolarHBondContact O-N 3.19Å
213	K	47.6	Very low	60.8	Low	166 Å²	166	146.3 Å²	146.3	72%	0.722	68%	0.68	S	S	*	*	H	α-helix	trans	-86.3	-42.4	-176	-76.5	-176.7	177.5	175	0	113.5	G215 R216 E217	K213-G215 PolarHBondContact O-N 3.31Å; K213-R216 PolarHBondContact O-N 3.02Å; K213-E217 PolarHBondContact O-N 2.89Å
214	K	43.9	Very low	59.2	Low	175 Å²	175	141.8 Å²	141.8	76%	0.761	67%	0.67	S	S	*	*	H	α-helix	trans	-68.9	-28.6	-179.3	-72.4	-170.4	177.7	-179.1	0	114.5	R218	K214-R218 PolarHBondContact O-N 2.91Å
215	G	48.7	Very low	57.7	Low	47 Å²	47	142 Å²	142	49%	0.485	67%	0.671	S	S	.	*	H	α-helix	trans	-74.4	-39	177.2	0	0	0	0	0	113.3	K213 K219	K213-G215 PolarHBondContact O-N 3.31Å; G215-K219 PolarHBondContact O-N 3.28Å; G215-K219 VanDerWaalsContact O-N 3.07Å
216	R	49.8	Very low	56.3	Low	209 Å²	209	137.2 Å²	137.2	79%	0.789	65%	0.652	S	S	*	*	H	α-helix	trans	-68.8	-37.3	175.6	-97.3	-178.8	170.1	178.7	-3.8	112	K213 K219 R220	K213-R216 PolarHBondContact O-N 3.02Å; R216-K219 PolarHBondContact O-N 2.79Å; R216-R220 WeakPolarHBondContact O-CB 3.49Å; R216-R220 PolarHBondContact O-N 2.84Å
217	E	52.7	Low	54.6	Low	103 Å²	103	140.9 Å²	140.9	48%	0.481	66%	0.663	S	S	.	*	H	α-helix	trans	-69.1	-38.7	177.1	-155.5	-171.5	146.4	0	0	112.3	K213 R220 K221	K213-E217 PolarHBondContact O-N 2.89Å; E217-R220 PolarHBondContact O-N 2.9Å; E217-K221 WeakPolarHBondContact O-CB 3.27Å; E217-K221 WeakPolarHBondContact O-CG 3.41Å; E217-K221 PolarHBondContact O-N 2.84Å; E217-K221 IonicContact OE1-NZ 2.77Å; E217-K221 PolarHBondContact OE1-NZ 3.49Å
218	R	54.4	Low	53.3	Low	205 Å²	205	143.7 Å²	143.7	77%	0.774	66%	0.662	S	S	*	*	H	α-helix	trans	-63.9	-37.8	171.5	-80	-177.3	175.1	-177.5	-2	112.6	K214 K222	K214-R218 PolarHBondContact O-N 2.91Å; R218-K222 WeakPolarHBondContact O-CB 3.21Å; R218-K222 PolarHBondContact O-N 2.92Å
219	K	54.1	Low	52.2	Low	149 Å²	149	141.4 Å²	141.4	65%	0.648	65%	0.652	S	S	*	*	H	α-helix	trans	-70.3	-39.4	176.4	-160.7	175.4	-175.8	-178.1	0	112	G215 R216 K222 L223	G215-K219 PolarHBondContact O-N 3.28Å; G215-K219 VanDerWaalsContact O-N 3.07Å; R216-K219 PolarHBondContact O-N 2.79Å; K219-K222 PolarHBondContact O-N 2.78Å; K219-L223 HydrophobicContact CG-CD1 4.37Å; K219-L223 WeakPolarHBondContact O-CG 3.46Å; K219-L223 PolarHBondContact O-N 3.01Å
220	R	56.2	Low	51.6	Low	192 Å²	192	146.3 Å²	146.3	73%	0.725	66%	0.66	S	S	*	*	H	α-helix	trans	-69.6	-36.1	176.6	-152.6	173.1	-173.9	172.8	1.4	112.3	R216 E217 K222 N224	R216-R220 WeakPolarHBondContact O-CB 3.49Å; R216-R220 PolarHBondContact O-N 2.84Å; E217-R220 PolarHBondContact O-N 2.9Å; R220-K222 VanDerWaalsContact C-N 3.34Å; R220-N224 WeakPolarHBondContact O-CB 3.42Å; R220-N224 PolarHBondContact O-N 2.83Å; R220-N224 VanDerWaalsContact O-N 3.09Å
221	K	58	Low	51.3	Low	136 Å²	136	143.9 Å²	143.9	59%	0.591	66%	0.658	S	S	*	*	H	α-helix	trans	-69.6	-26.6	170.9	-79.6	175.2	171.8	158.7	0	113.3	E217 K225	E217-K221 WeakPolarHBondContact O-CB 3.27Å; E217-K221 WeakPolarHBondContact O-CG 3.41Å; E217-K221 PolarHBondContact O-N 2.84Å; E217-K221 IonicContact OE1-NZ 2.77Å; E217-K221 PolarHBondContact OE1-NZ 3.49Å; K221-K225 WeakPolarHBondContact O-CB 3.34Å; K221-K225 PolarHBondContact O-N 2.87Å
222	K	57.1	Low	51.3	Low	141 Å²	141	137 Å²	137	61%	0.613	65%	0.646	S	S	*	*	H	α-helix	trans	-77.5	-42.7	176.2	-150.5	178.3	-177.4	-167.8	0	111.6	R218 K219 R220 K225 E226	R218-K222 WeakPolarHBondContact O-CB 3.21Å; R218-K222 PolarHBondContact O-N 2.92Å; K219-K222 PolarHBondContact O-N 2.78Å; R220-K222 VanDerWaalsContact C-N 3.34Å; K222-K225 PolarHBondContact O-N 2.04Å; K222-E226 PolarHBondContact O-N 3.4Å; K222-E226 VanDerWaalsContact O-N 3.15Å
223	L	57.1	Low	51	Low	95 Å²	95	138.9 Å²	138.9	50%	0.497	65%	0.651	S	S	.	*	H	α-helix	trans	-63.9	-45.1	174.7	-72.5	160.2	0	0	0	112.2	K219 K225 E226 E227	K219-L223 HydrophobicContact CG-CD1 4.37Å; K219-L223 WeakPolarHBondContact O-CG 3.46Å; K219-L223 PolarHBondContact O-N 3.01Å; L223-K225 PolarHBondContact O-N 2.81Å; L223-E226 PolarHBondContact O-N 2.81Å; L223-E226 VanDerWaalsContact O-N 3.17Å; L223-E227 PolarHBondContact O-N 3.11Å
224	N	54.8	Low	50.6	Low	98 Å²	98	138.5 Å²	138.5	52%	0.524	66%	0.657	S	S	.	*	H	α-helix	trans	-66.7	-18.1	175	-85.7	19.8	0	0	0	114.2	R220	R220-N224 WeakPolarHBondContact O-CB 3.42Å; R220-N224 PolarHBondContact O-N 2.83Å; R220-N224 VanDerWaalsContact O-N 3.09Å
225	K	56.4	Low	50.3	Low	161 Å²	161	135.2 Å²	135.2	70%	0.7	66%	0.656	S	S	*	*	H	α-helix	trans	-87.6	-24	176.6	-170.4	173.5	-178.5	178.1	0	111.8	K221 K222 L223	K221-K225 WeakPolarHBondContact O-CB 3.34Å; K221-K225 PolarHBondContact O-N 2.87Å; K222-K225 PolarHBondContact O-N 2.04Å; L223-K225 PolarHBondContact O-N 2.81Å
226	E	54.4	Low	49.5	Very low	105 Å²	105	143 Å²	143	49%	0.491	68%	0.677	S	S	.	*	H	α-helix	trans	-81.5	-41.6	174.4	-74.3	168.7	-177	0	0	110.5	K222 L223 K228 K229 E230	K222-E226 PolarHBondContact O-N 3.4Å; K222-E226 VanDerWaalsContact O-N 3.15Å; L223-E226 PolarHBondContact O-N 2.81Å; L223-E226 VanDerWaalsContact O-N 3.17Å; E226-K228 PolarHBondContact O-N 3.1Å; E226-K229 WeakPolarHBondContact O-CB 3.32Å; E226-K229 PolarHBondContact O-N 2.78Å; E226-E230 PolarHBondContact O-N 2.94Å
227	E	50	Low	48.7	Very low	131 Å²	131	136.4 Å²	136.4	61%	0.612	67%	0.674	S	S	*	*	H	α-helix	trans	-62.8	-34.4	174	-100.4	177.7	153.7	0	0	114	L223 K229 T231	L223-E227 PolarHBondContact O-N 3.11Å; E227-K229 VanDerWaalsContact C-N 3.26Å; E227-K229 PolarHBondContact O-N 2.03Å; E227-T231 PolarHBondContact O-OG1 3.07Å
228	K	50.6	Low	48	Very low	172 Å²	172	139.9 Å²	139.9	75%	0.748	69%	0.694	S	S	*	*	H	α-helix	trans	-74.9	-13.1	174.1	-87.6	-170.8	174	-169.9	0	113.8	E226	E226-K228 PolarHBondContact O-N 3.1Å
229	K	49.1	Very low	46.8	Very low	161 Å²	161	139.8 Å²	139.8	70%	0.7	70%	0.703	S	S	*	*	H	α-helix	trans	-91	-29.4	-179.9	-128.3	-176.1	178.3	-164.8	0	111.9	E226 E227	E226-K229 WeakPolarHBondContact O-CB 3.32Å; E226-K229 PolarHBondContact O-N 2.78Å; E227-K229 VanDerWaalsContact C-N 3.26Å; E227-K229 PolarHBondContact O-N 2.03Å
230	E	42.8	Very low	45.9	Very low	158 Å²	158	137.9 Å²	137.9	74%	0.738	71%	0.708	S	S	*	*	H	α-helix	trans	-79.4	-17.9	178.3	-69.9	-178.7	166.2	0	0	113.6	E226	E226-E230 PolarHBondContact O-N 2.94Å
231	T	44.4	Very low	45.3	Very low	126 Å²	126	134.1 Å²	134.1	77%	0.773	71%	0.712	S	S	*	*	T	Hydrogen-bonded Turn	trans	-93.2	8	179.2	28.6	0	0	0	0	114.8	E227	E227-T231 PolarHBondContact O-OG1 3.07Å
232	S	48.7	Very low	44.5	Very low	95 Å²	95	139.2 Å²	139.2	66%	0.664	73%	0.727	S	S	*	*	S	Bend	trans	-127.3	3.9	179.6	71.2	0	0	0	0	115.1
233	S	40.3	Very low	43.9	Very low	92 Å²	92	139.4 Å²	139.4	64%	0.643	73%	0.73	S	S	*	*			trans	-104.8	51.6	-178	60.2	0	0	0	0	112.9
234	D	39.9	Very low	43.5	Very low	158 Å²	158	138.4 Å²	138.4	85%	0.845	73%	0.728	S	S	*	*			trans	-133.6	78.3	159.5	-112.5	-25.4	0	0	0	109.2
235	S	36.3	Very low	43.3	Very low	106 Å²	106	138.9 Å²	138.9	74%	0.741	74%	0.736	S	S	*	*	S	Bend	trans	176.3	112.7	148.5	-79.8	0	0	0	0	111.8
236	K	31.9	Very low	42.9	Very low	210 Å²	210	138.5 Å²	138.5	91%	0.913	74%	0.737	S	S	*	*			trans	77.4	119.5	149.7	-63.7	178.8	177.4	179.4	0	118.3
237	G	32.9	Very low	42.6	Very low	70 Å²	70	139 Å²	139	72%	0.722	74%	0.74	S	S	*	*			trans	-92.7	-174.6	178	0	0	0	0	0	115
238	L	37.9	Very low	42.6	Very low	176 Å²	176	141.5 Å²	141.5	92%	0.921	74%	0.743	S	S	*	*			trans	60.1	106.1	169.4	-86.3	81	0	0	0	117.4
239	E	29.4	Very low	42.8	Very low	203 Å²	203	140 Å²	140	95%	0.949	74%	0.739	S	S	*	*				-167.4	163.1	116.9	-115.3	177.1	161.1	0	0	114.9
240	S	34.6	Very low	43	Very low	109 Å²	109	137.4 Å²	137.4	76%	0.762	73%	0.733	S	S	*	*			trans	-72.6	156.2	-157.8	176.5	0	0	0	0	117.2
241	S	44.1	Very low	43.5	Very low	114 Å²	114	137 Å²	137	80%	0.797	73%	0.729	S	S	*	*			trans	-63	131.9	176.1	-51.3	0	0	0	0	114.1
242	R	41.6	Very low	44.1	Very low	243 Å²	243	136 Å²	136	92%	0.917	72%	0.719	S	S	*	*			trans	-136.3	117	155.9	-77.2	-174.8	177.9	171.1	0.4	110.1
243	E	43.8	Very low	44.5	Very low	145 Å²	145	140.1 Å²	140.1	68%	0.678	72%	0.72	S	S	*	*			trans	-72.9	136.9	167.8	-71.7	-175.2	154.7	0	0	109.7
244	T	49.8	Very low	45.2	Very low	73 Å²	73	141.7 Å²	141.7	45%	0.448	72%	0.717	S	S	.	*			trans	-78.9	147.5	-177.5	37.4	0	0	0	0	112.5	E246 Q247	T244-E246 PolarHBondContact O-N 2.9Å; T244-E246 VanDerWaalsContact O-N 3.12Å; T244-Q247 PolarHBondContact O-N 3.2Å
245	P	50.1	Low	46.2	Very low	108 Å²	108	139.5 Å²	139.5	70%	0.701	70%	0.702	S	S	*	*	H	α-helix	trans	-54.3	-32	-177.7	-27	34.6	0	0	0	115	Q247 R248 E249	P245-Q247 PolarHBondContact O-N 3.26Å; P245-R248 PolarHBondContact O-N 3.31Å; P245-E249 PolarHBondContact O-N 3.15Å
246	E	48.6	Very low	47.4	Very low	153 Å²	153	140.4 Å²	140.4	72%	0.715	69%	0.694	S	S	*	*	H	α-helix	trans	-64.8	-24.4	178.8	-71.4	-178.9	139.1	0	0	113.7	T244	T244-E246 PolarHBondContact O-N 2.9Å; T244-E246 VanDerWaalsContact O-N 3.12Å
247	Q	47.4	Very low	48.8	Very low	116 Å²	116	137.3 Å²	137.3	54%	0.542	68%	0.683	S	S	.	*	H	α-helix	trans	-80.7	-22.8	178.9	-65.4	-172.7	-12.2	0	0	112.7	T244 P245	T244-Q247 PolarHBondContact O-N 3.2Å; P245-Q247 PolarHBondContact O-N 3.26Å
248	R	51.4	Low	50	Low	183 Å²	183	141.1 Å²	141.1	69%	0.691	68%	0.679	S	S	*	*	H	α-helix	trans	-77.6	-44.7	174.2	-87.9	-178.7	176.7	-175.9	-2.8	112.1	P245 N250 K251 D252	P245-R248 PolarHBondContact O-N 3.31Å; R248-N250 VanDerWaalsContact C-N 3.27Å; R248-N250 PolarHBondContact O-N 3.24Å; R248-K251 PolarHBondContact O-N 3.07Å; R248-D252 PolarHBondContact O-N 3.16Å
249	E	54.3	Low	51.1	Low	140 Å²	140	140.9 Å²	140.9	65%	0.654	67%	0.666	S	S	*	*	H	α-helix	trans	-62.4	-33.8	179.5	-81	-168.4	134.9	0	0	113.2	P245 R253	P245-E249 PolarHBondContact O-N 3.15Å; E249-R253 PolarHBondContact O-N 3.08Å; E249-R253 VanDerWaalsContact O-N 3.13Å
250	N	52.1	Low	52.6	Low	108 Å²	108	138.1 Å²	138.1	58%	0.578	65%	0.651	S	S	*	*	H	α-helix	trans	-73.5	-30.1	-179.7	-113.6	-25.3	0	0	0	113.2	R248 Q254	R248-N250 VanDerWaalsContact C-N 3.27Å; R248-N250 PolarHBondContact O-N 3.24Å; N250-Q254 PolarHBondContact O-N 2.79Å
251	K	54.1	Low	53.8	Low	149 Å²	149	135.8 Å²	135.8	65%	0.648	64%	0.639	S	S	*	*	H	α-helix	trans	-72.1	-41.3	174	-103.4	178.3	176.7	173	0	111.5	R248 Q254 Q255	R248-K251 PolarHBondContact O-N 3.07Å; K251-Q254 PolarHBondContact O-N 2.03Å; K251-Q255 PolarHBondContact O-N 2.8Å
252	D	56.6	Low	54.7	Low	106 Å²	106	136.6 Å²	136.6	57%	0.567	63%	0.63	S	S	*	*	H	α-helix	trans	-67.3	-38.8	179.7	-73.4	-25.2	0	0	0	112.1	R248 Q254 Q255 Q256	R248-D252 PolarHBondContact O-N 3.16Å; D252-Q254 PolarHBondContact O-N 3.08Å; D252-Q255 PolarHBondContact O-N 2.74Å; D252-Q256 WeakPolarHBondContact O-CB 3.45Å; D252-Q256 PolarHBondContact O-N 3.4Å
253	R	57.6	Low	55.6	Low	180 Å²	180	131.5 Å²	131.5	68%	0.679	62%	0.616	S	S	*	*	H	α-helix	trans	-62.6	-41	173.9	-82.7	-176	166.9	-164.2	-1.3	113.2	E249 Q255 Q257	E249-R253 PolarHBondContact O-N 3.08Å; E249-R253 VanDerWaalsContact O-N 3.13Å; R253-Q255 VanDerWaalsContact C-N 3.34Å; R253-Q257 WeakPolarHBondContact O-CG 3.45Å; R253-Q257 PolarHBondContact O-N 3.26Å
254	Q	55.8	Low	56.3	Low	125 Å²	125	132.9 Å²	132.9	58%	0.584	62%	0.62	S	S	*	*	H	α-helix	trans	-68.7	-33.3	177.1	-79.7	-174.1	-1.6	0	0	112.4	N250 K251 D252 K258	N250-Q254 PolarHBondContact O-N 2.79Å; K251-Q254 PolarHBondContact O-N 2.03Å; D252-Q254 PolarHBondContact O-N 3.08Å; Q254-K258 PolarHBondContact O-N 2.03Å
255	Q	60.3	Low	56.6	Low	113 Å²	113	136 Å²	136	53%	0.528	63%	0.63	S	S	.	*	H	α-helix	trans	-76.5	-33.3	179.9	-154.6	159.1	6.9	0	0	112	K251 D252 R253 K258 R259	K251-Q255 PolarHBondContact O-N 2.8Å; D252-Q255 PolarHBondContact O-N 2.74Å; R253-Q255 VanDerWaalsContact C-N 3.34Å; Q255-K258 PolarHBondContact O-N 3.03Å; Q255-R259 PolarHBondContact O-N 2.95Å
256	Q	61.2	Low	57	Low	125 Å²	125	137.9 Å²	137.9	58%	0.584	63%	0.629	S	S	*	*	H	α-helix	trans	-72.3	-33.5	175.9	-146	174.8	23.4	0	0	112.8	D252 K260	D252-Q256 WeakPolarHBondContact O-CB 3.45Å; D252-Q256 PolarHBondContact O-N 3.4Å; Q256-K260 PolarHBondContact O-N 3.34Å
257	Q	60.8	Low	57.4	Low	145 Å²	145	138.7 Å²	138.7	68%	0.678	63%	0.63	S	S	*	*	H	α-helix	trans	-67.8	-36.7	173.7	-77.1	-179.3	-5.8	0	0	112.6	R253 A261	R253-Q257 WeakPolarHBondContact O-CG 3.45Å; R253-Q257 PolarHBondContact O-N 3.26Å; Q257-A261 PolarHBondContact O-N 2.97Å
258	K	58.7	Low	57.8	Low	149 Å²	149	136.8 Å²	136.8	65%	0.648	63%	0.63	S	S	*	*	H	α-helix	trans	-67.1	-38	176.4	-75.6	-178.3	179.3	-178.6	0	112.9	Q254 Q255 A261 Q262	Q254-K258 PolarHBondContact O-N 2.03Å; Q255-K258 PolarHBondContact O-N 3.03Å; K258-A261 PolarHBondContact O-N 3.16Å; K258-Q262 PolarHBondContact O-N 3.49Å
259	R	61.8	Low	57.9	Low	171 Å²	171	133.2 Å²	133.2	65%	0.645	63%	0.628	S	S	*	*	H	α-helix	trans	-66.9	-41.5	177.1	-70.9	-175.3	-178	-165.2	2	112.6	Q255 A261 Q262 E263	Q255-R259 PolarHBondContact O-N 2.95Å; R259-A261 VanDerWaalsContact C-N 3.29Å; R259-A261 PolarHBondContact O-N 3.23Å; R259-Q262 PolarHBondContact O-N 2.76Å; R259-E263 PolarHBondContact O-N 3.41Å
260	K	61	Low	58	Low	146 Å²	146	131.1 Å²	131.1	64%	0.635	63%	0.629	S	S	*	*	H	α-helix	trans	-66.5	-28.1	176.9	-72.6	-176	177.8	-178.1	0	113.5	Q256	Q256-K260 PolarHBondContact O-N 3.34Å
261	A	59.3	Low	58.2	Low	60 Å²	60	132.9 Å²	132.9	50%	0.496	64%	0.636	S	S	.	*	H	α-helix	trans	-72.1	-35.8	174.9	0	0	0	0	0	112.3	Q257 K258 R259	Q257-A261 PolarHBondContact O-N 2.97Å; K258-A261 PolarHBondContact O-N 3.16Å; R259-A261 VanDerWaalsContact C-N 3.29Å; R259-A261 PolarHBondContact O-N 3.23Å
262	Q	62.3	Low	58.2	Low	131 Å²	131	130.9 Å²	130.9	61%	0.612	64%	0.641	S	S	*	*	H	α-helix	trans	-73.5	-39.2	179.6	-73.6	177.6	-39.6	0	0	112.8	K258 R259 K264 Q265 Q266	K258-Q262 PolarHBondContact O-N 3.49Å; R259-Q262 PolarHBondContact O-N 2.76Å; Q262-K264 VanDerWaalsContact C-N 3.3Å; Q262-K264 PolarHBondContact O-N 3.27Å; Q262-Q265 PolarHBondContact O-N 2.88Å; Q262-Q266 PolarHBondContact O-N 3.41Å
263	E	59.9	Low	58	Low	135 Å²	135	131.7 Å²	131.7	63%	0.631	65%	0.65	S	S	*	*	H	α-helix	trans	-65.7	-31.3	175.9	-78.6	-178	146.8	0	0	113.2	R259 Q265 Q266 K267	R259-E263 PolarHBondContact O-N 3.41Å; E263-Q265 VanDerWaalsContact C-N 3.28Å; E263-Q265 PolarHBondContact O-N 2.86Å; E263-Q266 PolarHBondContact O-N 2.96Å; E263-K267 PolarHBondContact O-N 2.8Å
264	K	58.5	Low	57.6	Low	174 Å²	174	129.3 Å²	129.3	76%	0.757	66%	0.656	S	S	*	*	H	α-helix	trans	-70	-27.8	178.3	-133.6	178.2	-175.2	-175.6	0	112.4	Q262	Q262-K264 VanDerWaalsContact C-N 3.3Å; Q262-K264 PolarHBondContact O-N 3.27Å
265	Q	57.6	Low	57	Low	139 Å²	139	136 Å²	136	65%	0.65	69%	0.686	S	S	*	*	H	α-helix	trans	-82.8	-23.9	179.6	-141.7	164	2.4	0	0	112.3	Q262 E263 S268	Q262-Q265 PolarHBondContact O-N 2.88Å; E263-Q265 VanDerWaalsContact C-N 3.28Å; E263-Q265 PolarHBondContact O-N 2.86Å; Q265-S268 PolarHBondContact O-OG 2.67Å; Q265-S268 VanDerWaalsContact O-OG 3.06Å
266	Q	57.8	Low	56.8	Low	148 Å²	148	137.1 Å²	137.1	69%	0.692	69%	0.694	S	S	*	*	H	α-helix	trans	-83.3	-30	178.1	-130.5	160.6	3.5	0	0	112.8	Q262 E263 S270	Q262-Q266 PolarHBondContact O-N 3.41Å; E263-Q266 PolarHBondContact O-N 2.96Å; Q266-S270 PolarHBondContact O-OG 3.18Å; Q266-S270 VanDerWaalsContact O-OG 3.1Å
267	K	58	Low	56.6	Low	170 Å²	170	137.7 Å²	137.7	74%	0.739	70%	0.7	S	S	*	*	H	α-helix	trans	-73.4	-24.2	174.5	-85.8	-177.3	175.8	179.1	0	114.5	E263	E263-K267 PolarHBondContact O-N 2.8Å
268	S	54.5	Low	56.3	Low	76 Å²	76	137.3 Å²	137.3	53%	0.531	70%	0.701	S	S	.	*	T	Hydrogen-bonded Turn	trans	-77.6	-21.4	178	53.6	0	0	0	0	114	Q265	Q265-S268 PolarHBondContact O-OG 2.67Å; Q265-S268 VanDerWaalsContact O-OG 3.06Å
269	V	54.6	Low	56.2	Low	108 Å²	108	136.6 Å²	136.6	66%	0.655	70%	0.704	S	S	*	*	T	Hydrogen-bonded Turn	trans	-86.1	-18.3	-179.6	-176.9	0	0	0	0	112.1
270	S	55.6	Low	55.9	Low	95 Å²	95	134.5 Å²	134.5	66%	0.664	71%	0.708	S	S	*	*	T	Hydrogen-bonded Turn	trans	-87.7	-2.8	-173.4	-47.9	0	0	0	0	114.8	Q266	Q266-S270 PolarHBondContact O-OG 3.18Å; Q266-S270 VanDerWaalsContact O-OG 3.1Å
271	I	55.9	Low	55.5	Low	145 Å²	145	133.7 Å²	133.7	74%	0.744	71%	0.713	S	S	*	*	T	Hydrogen-bonded Turn	trans	-102.9	-6.1	-174.6	-67.1	173.2	0	0	0	112.6
272	S	54.7	Low	55.2	Low	107 Å²	107	139 Å²	139	75%	0.748	73%	0.728	S	S	*	*	S	Bend	trans	-102.7	27.4	-176.5	-59.8	0	0	0	0	114.9
273	T	53.1	Low	54.7	Low	123 Å²	123	139.6 Å²	139.6	76%	0.755	74%	0.737	S	S	*	*	S	Bend	trans	-137.4	34.4	-178.8	-28.3	0	0	0	0	114.9
274	V	47.7	Very low	54.3	Low	131 Å²	131	140 Å²	140	79%	0.794	75%	0.746	S	S	*	*			trans	-143.7	89.8	160.5	-173.1	0	0	0	0	109.6
275	H	43.3	Very low	53.9	Low	264 Å²	264	136.9 Å²	136.9	100%	1.222	75%	0.745	S	S	*	*			trans	-169.2	0	138.3	-99.7	-38.1	0	0	0	109.9

Retrieved 275 of 275 residues in 40.8 ms (Link to these results)

U.S. Privacy Notice - Disclaimer / Registrations / Copyright Statement - Linking Policy - Notice of Privacy Practices (HIPAA) - Notice of Non‑Discrimination
© Copyright 2026 St. Jude Children's Research Hospital, a not-for-profit, section 501(c)(3).