A0A061IFV3_CRIGR Loading...

Solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6

AlphaFold DB , UniProt , Accession A0A061IFV3, Species CRIGR (Cricetulus griseus, Chinese hamster), Gene Slc17a6, Length 582 aa.

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	38.8	Very low	40.5	Very low	242 Å²	242	166.1 Å²	166.1	100%	1.192	85%	0.852	S	S	*	*				0	64.8	0	-151.5	166.1	176.2	0	0	107.3	S3	M1-S3 PolarHBondContact O-N 3.37Å
2	E	39.5	Very low	40.8	Very low	201 Å²	201	156 Å²	156	94%	0.939	82%	0.819	S	S	*	*			trans	-81.5	96.6	172.4	-72.6	169.3	130	0	0	106.9
3	S	45.3	Very low	41.7	Very low	101 Å²	101	158.5 Å²	158.5	71%	0.706	82%	0.819	S	S	*	*			trans	-162.9	142.2	166.9	-172.5	0	0	0	0	107.2	M1	M1-S3 PolarHBondContact O-N 3.37Å
4	V	38.8	Very low	42.5	Very low	121 Å²	121	158 Å²	158	73%	0.733	81%	0.811	S	S	*	*	S	Bend	trans	94.3	-22.2	167.4	-165	0	0	0	0	117.9
5	K	35.8	Very low	43.1	Very low	221 Å²	221	150.3 Å²	150.3	96%	0.961	79%	0.786	S	S	*	*	T	Hydrogen-bonded Turn	trans	-88.2	2.1	-178.9	-103	-175.5	-179.9	-178	0	117.8
6	Q	36.7	Very low	44	Very low	197 Å²	197	147.2 Å²	147.2	92%	0.921	77%	0.769	S	S	*	*	T	Hydrogen-bonded Turn	trans	-120.3	14.1	-176.3	-113.9	-179.4	-0.7	0	0	115.6
7	R	39.6	Very low	44.6	Very low	238 Å²	238	148 Å²	148	90%	0.898	77%	0.765	S	S	*	*	S	Bend	trans	-110.8	7.8	-172	-101	-174.2	-176.6	-178.5	1.9	117.4
8	I	43.9	Very low	45.3	Very low	148 Å²	148	145.9 Å²	145.9	76%	0.759	76%	0.756	S	S	*	*	S	Bend	trans	-118.3	-11.2	-169.9	-64	-177.6	0	0	0	115.9
9	L	42.6	Very low	46.1	Very low	173 Å²	173	146.1 Å²	146.1	91%	0.906	75%	0.75	S	S	*	*	S	Bend	trans	-139.5	90.7	-176.5	-76.5	162.6	0	0	0	112.7
10	A	39.2	Very low	46.9	Very low	86 Å²	86	140.8 Å²	140.8	71%	0.711	73%	0.73	S	S	*	*			trans	161.5	112	139.9	0	0	0	0	0	109.4	G12	A10-G12 PolarHBondContact O-N 3.1Å; A10-G12 VanDerWaalsContact O-N 3.1Å
11	P	45.3	Very low	47.9	Very low	99 Å²	99	136.2 Å²	136.2	64%	0.643	72%	0.717	S	S	*	*			trans	-67.1	110.2	154	15.7	-3.7	0	0	0	105.8	I16	P11-I16 HydrophobicContact CB-CD1 4.49Å; P11-I16 HydrophobicContact CB-CG1 4.23Å; P11-I16 HydrophobicContact CG-CD1 4.26Å; P11-I16 HydrophobicContact CG-CG1 4.44Å
12	G	44.6	Very low	49.1	Very low	45 Å²	45	132.2 Å²	132.2	46%	0.464	69%	0.693	S	S	.	*			trans	-49.4	145.5	178.5	0	0	0	0	0	110.7	A10 E14 G15 I16	A10-G12 PolarHBondContact O-N 3.1Å; A10-G12 VanDerWaalsContact O-N 3.1Å; G12-E14 PolarHBondContact O-N 3.47Å; G12-G15 PolarHBondContact O-N 2.77Å; G12-I16 PolarHBondContact O-N 3.03Å
13	K	52.4	Low	50	Low	188 Å²	188	124.5 Å²	124.5	82%	0.817	66%	0.661	S	S	*	*	H	α-helix	trans	-44.9	-29	179.7	-82.7	179.8	172.7	177.9	0	113.3	K17	K13-K17 WeakPolarHBondContact O-CB 3.29Å; K13-K17 PolarHBondContact O-N 3.32Å
14	E	52.3	Low	50.8	Low	152 Å²	152	125.1 Å²	125.1	71%	0.71	66%	0.656	S	S	*	*	H	α-helix	trans	-71.2	-36.3	175.5	-69.4	-175.6	149.3	0	0	114.4	G12 K17 N18	G12-E14 PolarHBondContact O-N 3.47Å; E14-K17 PolarHBondContact O-N 2.92Å; E14-N18 VanDerWaalsContact O-CB 3.28Å; E14-N18 WeakPolarHBondContact O-CB 3.3Å; E14-N18 PolarHBondContact O-N 3.34Å
15	G	52.3	Low	52.1	Low	42 Å²	42	121 Å²	121	43%	0.433	64%	0.638	S	S	.	*	H	α-helix	trans	-67.4	-39.7	176.4	0	0	0	0	0	112.1	G12 F19	G12-G15 PolarHBondContact O-N 2.77Å; G15-F19 VanDerWaalsContact O-CB 3.29Å; G15-F19 WeakPolarHBondContact O-CB 3.4Å; G15-F19 PolarHBondContact O-N 2.86Å
16	I	57.1	Low	53.1	Low	101 Å²	101	117 Å²	117	52%	0.518	62%	0.622	S	S	.	*	H	α-helix	trans	-70.7	-40.2	174.8	-59.1	175.9	0	0	0	110.5	P11 G12 F19 A20	P11-I16 HydrophobicContact CB-CD1 4.49Å; P11-I16 HydrophobicContact CB-CG1 4.23Å; P11-I16 HydrophobicContact CG-CD1 4.26Å; P11-I16 HydrophobicContact CG-CG1 4.44Å; G12-I16 PolarHBondContact O-N 3.03Å; I16-F19 PolarHBondContact O-N 2.97Å; I16-A20 WeakPolarHBondContact O-CB 3.13Å; I16-A20 PolarHBondContact O-N 2.8Å
17	K	53.5	Low	54.1	Low	161 Å²	161	112.1 Å²	112.1	70%	0.7	60%	0.602	S	S	*	*	H	α-helix	trans	-62.3	-42.2	173.4	-97.8	-174.1	170.9	-175.2	0	112.6	K13 E14 G21	K13-K17 WeakPolarHBondContact O-CB 3.29Å; K13-K17 PolarHBondContact O-N 3.32Å; E14-K17 PolarHBondContact O-N 2.92Å; K17-G21 PolarHBondContact O-N 3.28Å
18	N	58.3	Low	54.6	Low	111 Å²	111	108.6 Å²	108.6	59%	0.594	59%	0.59	S	S	*	*	H	α-helix	trans	-72.5	-35	179.7	-79.2	-19.9	0	0	0	112.2	E14 K22	E14-N18 VanDerWaalsContact O-CB 3.28Å; E14-N18 WeakPolarHBondContact O-CB 3.3Å; E14-N18 PolarHBondContact O-N 3.34Å; N18-K22 VanDerWaalsContact O-CB 3.32Å; N18-K22 WeakPolarHBondContact O-CB 3.32Å; N18-K22 VanDerWaalsContact O-CG 3.3Å; N18-K22 WeakPolarHBondContact O-CG 3.28Å; N18-K22 PolarHBondContact O-N 3.46Å
19	F	60.5	Low	54.9	Low	148 Å²	148	110.3 Å²	110.3	65%	0.649	59%	0.587	S	S	*	*	H	α-helix	trans	-70.7	-45	173.1	-170.7	-97.3	0	0	0	111.4	G15 I16 G21 K22 S23	G15-F19 VanDerWaalsContact O-CB 3.29Å; G15-F19 WeakPolarHBondContact O-CB 3.4Å; G15-F19 PolarHBondContact O-N 2.86Å; I16-F19 PolarHBondContact O-N 2.97Å; F19-G21 VanDerWaalsContact C-N 3.35Å; F19-G21 PolarHBondContact O-N 2.84Å; F19-K22 PolarHBondContact O-N 3.42Å; F19-S23 WeakPolarHBondContact O-CB 3.34Å; F19-S23 PolarHBondContact O-N 3.36Å; F19-S23 PolarHBondContact O-OG 3.14Å
20	A	61.7	Low	55.4	Low	41 Å²	41	106.1 Å²	106.1	34%	0.339	57%	0.568	S	S	.	*	H	α-helix	trans	-61.9	-41.4	174.7	0	0	0	0	0	111.6	I16 L24	I16-A20 WeakPolarHBondContact O-CB 3.13Å; I16-A20 PolarHBondContact O-N 2.8Å; A20-L24 WeakPolarHBondContact O-CB 3.36Å; A20-L24 WeakPolarHBondContact O-CD1 3.42Å; A20-L24 WeakPolarHBondContact O-CG 3.15Å; A20-L24 PolarHBondContact O-N 2.8Å
21	G	67.5	Low	55.9	Low	44 Å²	44	107 Å²	107	45%	0.454	56%	0.56	S	S	.	*	H	α-helix	trans	-66.7	-38	175.7	0	0	0	0	0	113.2	K17 F19 G25	K17-G21 PolarHBondContact O-N 3.28Å; F19-G21 VanDerWaalsContact C-N 3.35Å; F19-G21 PolarHBondContact O-N 2.84Å; G21-G25 PolarHBondContact O-N 3.46Å
22	K	63.7	Low	55.8	Low	159 Å²	159	108 Å²	108	69%	0.691	56%	0.556	S	S	*	*	H	α-helix	trans	-71.7	-41.4	174.4	-77.9	-179.4	178.7	-177.8	0	112.3	N18 F19 G25 Q26	N18-K22 VanDerWaalsContact O-CB 3.32Å; N18-K22 WeakPolarHBondContact O-CB 3.32Å; N18-K22 VanDerWaalsContact O-CG 3.3Å; N18-K22 WeakPolarHBondContact O-CG 3.28Å; N18-K22 PolarHBondContact O-N 3.46Å; F19-K22 PolarHBondContact O-N 3.42Å; K22-G25 PolarHBondContact O-N 2.79Å; K22-Q26 WeakPolarHBondContact O-CB 3.26Å; K22-Q26 PolarHBondContact O-N 3.33Å
23	S	58.6	Low	55.6	Low	39 Å²	39	114.3 Å²	114.3	27%	0.273	57%	0.571	S	S	.	*	H	α-helix	trans	-66.9	-42	174.6	-75.2	0	0	0	0	111.8	F19 Q26 I27	F19-S23 WeakPolarHBondContact O-CB 3.34Å; F19-S23 PolarHBondContact O-N 3.36Å; F19-S23 PolarHBondContact O-OG 3.14Å; S23-Q26 PolarHBondContact O-N 2.86Å; S23-I27 WeakPolarHBondContact O-CB 3.43Å; S23-I27 WeakPolarHBondContact O-CD1 3.37Å; S23-I27 WeakPolarHBondContact O-CG1 3.16Å; S23-I27 PolarHBondContact O-N 2.76Å
24	L	61.7	Low	55	Low	114 Å²	114	113.5 Å²	113.5	60%	0.597	57%	0.567	S	S	*	*	H	α-helix	trans	-63.5	-42.8	172.6	-84.3	157.4	0	0	0	110.9	A20 Q26 I27 Y28	A20-L24 WeakPolarHBondContact O-CB 3.36Å; A20-L24 WeakPolarHBondContact O-CD1 3.42Å; A20-L24 WeakPolarHBondContact O-CG 3.15Å; A20-L24 PolarHBondContact O-N 2.8Å; L24-Q26 VanDerWaalsContact C-N 3.33Å; L24-Q26 PolarHBondContact O-N 3.45Å; L24-I27 PolarHBondContact O-N 3.4Å; L24-Y28 VanDerWaalsContact O-CB 3.26Å; L24-Y28 WeakPolarHBondContact O-CB 3.41Å; L24-Y28 PolarHBondContact O-N 2.86Å
25	G	66.7	Low	54.3	Low	35 Å²	35	112.4 Å²	112.4	36%	0.361	56%	0.562	S	S	.	*	H	α-helix	trans	-65.2	-34.1	175.6	0	0	0	0	0	113.4	G21 K22 R29	G21-G25 PolarHBondContact O-N 3.46Å; K22-G25 PolarHBondContact O-N 2.79Å; G25-R29 WeakPolarHBondContact O-CB 3.29Å; G25-R29 PolarHBondContact O-N 3.27Å
26	Q	57.5	Low	53.5	Low	135 Å²	135	117.1 Å²	117.1	63%	0.631	58%	0.578	S	S	*	*	H	α-helix	trans	-71.2	-41.3	171.9	-108.7	173.2	-45.9	0	0	111.9	K22 S23 L24 Y28 R29 V30	K22-Q26 WeakPolarHBondContact O-CB 3.26Å; K22-Q26 PolarHBondContact O-N 3.33Å; S23-Q26 PolarHBondContact O-N 2.86Å; L24-Q26 VanDerWaalsContact C-N 3.33Å; L24-Q26 PolarHBondContact O-N 3.45Å; Q26-Y28 VanDerWaalsContact C-N 3.33Å; Q26-R29 PolarHBondContact O-N 2.82Å; Q26-V30 VanDerWaalsContact O-CB 3.25Å; Q26-V30 WeakPolarHBondContact O-CB 3.32Å; Q26-V30 WeakPolarHBondContact O-CG2 3.18Å; Q26-V30 PolarHBondContact O-N 2.81Å
27	I	57	Low	52.4	Low	96 Å²	96	115.5 Å²	115.5	49%	0.492	57%	0.573	S	S	.	*	H	α-helix	trans	-65	-40.2	175.1	-70.1	163.1	0	0	0	110	S23 L24 V30 L31	S23-I27 WeakPolarHBondContact O-CB 3.43Å; S23-I27 WeakPolarHBondContact O-CD1 3.37Å; S23-I27 WeakPolarHBondContact O-CG1 3.16Å; S23-I27 PolarHBondContact O-N 2.76Å; L24-I27 PolarHBondContact O-N 3.4Å; I27-V30 CarbonylContact O-C 3.56Å; I27-V30 PolarHBondContact O-N 2.95Å; I27-L31 HydrophobicContact CG2-CD1 3.76Å; I27-L31 HydrophobicContact CG2-CG 4.44Å; I27-L31 VanDerWaalsContact O-CB 3.29Å; I27-L31 WeakPolarHBondContact O-CB 3.11Å; I27-L31 WeakPolarHBondContact O-CG 3.3Å; I27-L31 PolarHBondContact O-N 2.97Å
28	Y	50.7	Low	51.6	Low	163 Å²	163	119.4 Å²	119.4	64%	0.639	58%	0.583	S	S	*	*	H	α-helix	trans	-65.8	-45.8	175.9	-146.1	-91.5	0	0	0	110.8	L24 Q26 V30 L31 E32	L24-Y28 VanDerWaalsContact O-CB 3.26Å; L24-Y28 WeakPolarHBondContact O-CB 3.41Å; L24-Y28 PolarHBondContact O-N 2.86Å; Q26-Y28 VanDerWaalsContact C-N 3.33Å; Y28-V30 VanDerWaalsContact C-N 3.3Å; Y28-V30 PolarHBondContact O-N 2.76Å; Y28-L31 PolarHBondContact O-N 3.29Å; Y28-E32 WeakPolarHBondContact O-CB 3.25Å; Y28-E32 PolarHBondContact O-N 2.74Å
29	R	50.3	Low	50.7	Low	185 Å²	185	120.1 Å²	120.1	70%	0.698	58%	0.583	S	S	*	*	H	α-helix	trans	-65.2	-29.2	173.2	-89.9	-177.1	174.7	171.3	-0.3	113.9	G25 Q26 K33	G25-R29 WeakPolarHBondContact O-CB 3.29Å; G25-R29 PolarHBondContact O-N 3.27Å; Q26-R29 PolarHBondContact O-N 2.82Å; R29-K33 VanDerWaalsContact O-CB 3.25Å; R29-K33 WeakPolarHBondContact O-CB 3.43Å; R29-K33 WeakPolarHBondContact O-CG 3.43Å; R29-K33 PolarHBondContact O-N 3.42Å
30	V	53.5	Low	49.6	Very low	85 Å²	85	118.8 Å²	118.8	52%	0.515	59%	0.587	S	S	.	*	H	α-helix	trans	-79.8	-32.7	176	168.9	0	0	0	0	111	Q26 I27 Y28 K34	Q26-V30 VanDerWaalsContact O-CB 3.25Å; Q26-V30 WeakPolarHBondContact O-CB 3.32Å; Q26-V30 WeakPolarHBondContact O-CG2 3.18Å; Q26-V30 PolarHBondContact O-N 2.81Å; I27-V30 CarbonylContact O-C 3.56Å; I27-V30 PolarHBondContact O-N 2.95Å; Y28-V30 VanDerWaalsContact C-N 3.3Å; Y28-V30 PolarHBondContact O-N 2.76Å; V30-K34 VanDerWaalsContact O-CB 3.3Å; V30-K34 WeakPolarHBondContact O-CB 3.36Å; V30-K34 PolarHBondContact O-N 3.26Å
31	L	48.7	Very low	48.9	Very low	105 Å²	105	121.7 Å²	121.7	55%	0.55	60%	0.596	S	S	.	*	H	α-helix	trans	-67.8	-44	169.2	-81.8	161.1	0	0	0	110.8	I27 Y28 K33 K34 Q35	I27-L31 HydrophobicContact CG2-CD1 3.76Å; I27-L31 HydrophobicContact CG2-CG 4.44Å; I27-L31 VanDerWaalsContact O-CB 3.29Å; I27-L31 WeakPolarHBondContact O-CB 3.11Å; I27-L31 WeakPolarHBondContact O-CG 3.3Å; I27-L31 PolarHBondContact O-N 2.97Å; Y28-L31 PolarHBondContact O-N 3.29Å; L31-K33 PolarHBondContact O-N 2.91Å; L31-K34 CarbonylContact O-C 3.59Å; L31-K34 WeakPolarHBondContact O-CA 3.45Å; L31-K34 PolarHBondContact O-N 2.83Å; L31-Q35 PolarHBondContact O-N 3.37Å
32	E	42.5	Very low	48.1	Very low	118 Å²	118	125.7 Å²	125.7	55%	0.551	60%	0.602	S	S	*	*	H	α-helix	trans	-68.8	-32.3	177.3	-161.5	177.4	-149.8	0	0	111.6	Y28	Y28-E32 WeakPolarHBondContact O-CB 3.25Å; Y28-E32 PolarHBondContact O-N 2.74Å
33	K	42	Very low	47.3	Very low	178 Å²	178	123.8 Å²	123.8	77%	0.774	60%	0.599	S	S	*	*	T	Hydrogen-bonded Turn	trans	-76.7	-17.4	167.7	-89.2	-172.2	170.4	-173.2	0	114.4	R29 L31	R29-K33 VanDerWaalsContact O-CB 3.25Å; R29-K33 WeakPolarHBondContact O-CB 3.43Å; R29-K33 WeakPolarHBondContact O-CG 3.43Å; R29-K33 PolarHBondContact O-N 3.42Å; L31-K33 PolarHBondContact O-N 2.91Å
34	K	38.9	Very low	47.1	Very low	171 Å²	171	124.7 Å²	124.7	74%	0.743	60%	0.603	S	S	*	*	T	Hydrogen-bonded Turn	trans	-92	-16.6	173.2	-92.9	-170.7	171.7	-172.2	0	112.7	V30 L31 D36	V30-K34 VanDerWaalsContact O-CB 3.3Å; V30-K34 WeakPolarHBondContact O-CB 3.36Å; V30-K34 PolarHBondContact O-N 3.26Å; L31-K34 CarbonylContact O-C 3.59Å; L31-K34 WeakPolarHBondContact O-CA 3.45Å; L31-K34 PolarHBondContact O-N 2.83Å; K34-D36 PolarHBondContact O-N 2.77Å
35	Q	37.7	Very low	46.6	Very low	129 Å²	129	129.2 Å²	129.2	60%	0.603	62%	0.621	S	S	*	*			trans	-72.1	60.7	159.9	-107.7	177.1	-30	0	0	108.7	L31 T37	L31-Q35 PolarHBondContact O-N 3.37Å; Q35-T37 PolarHBondContact O-N 2.84Å
36	D	36	Very low	45.9	Very low	142 Å²	142	134.3 Å²	134.3	76%	0.759	64%	0.64	S	S	*	*			trans	-83.5	64.5	172.5	-151	17.4	0	0	0	107.1	K34	K34-D36 PolarHBondContact O-N 2.77Å
37	T	34.1	Very low	45.3	Very low	67 Å²	67	130.1 Å²	130.1	41%	0.411	63%	0.633	S	S	.	*	S	Bend	trans	178.1	130.7	155.2	32.6	0	0	0	0	110	Q35 E39 E54	Q35-T37 PolarHBondContact O-N 2.84Å; T37-E39 VanDerWaalsContact C-N 3.34Å; T37-E39 PolarHBondContact O-N 3.03Å; T37-E54 VanDerWaalsContact CB-CD 3.46Å; T37-E54 WeakPolarHBondContact CB-OE1 3.49Å; T37-E54 VanDerWaalsContact CG2-CD 3.42Å; T37-E54 WeakPolarHBondContact CG2-OE1 3.25Å; T37-E54 WeakPolarHBondContact CG2-OE2 3.47Å; T37-E54 PolarHBondContact OG1-OE2 2.94Å
38	R	36.6	Very low	44.8	Very low	242 Å²	242	132.5 Å²	132.5	91%	0.913	64%	0.64	S	S	*	*			trans	-68	90.7	175.6	-80.3	177	171.2	172.7	-4	108.8	T40	R38-T40 PolarHBondContact O-N 3.5Å
39	E	39.2	Very low	44.5	Very low	127 Å²	127	129.1 Å²	129.1	59%	0.593	64%	0.638	S	S	*	*			trans	-69.1	95	166.2	-70.3	175.5	166.8	0	0	108.6	T37 I41	T37-E39 VanDerWaalsContact C-N 3.34Å; T37-E39 PolarHBondContact O-N 3.03Å; E39-I41 VanDerWaalsContact C-N 3.31Å; E39-I41 HydrophobicContact CB-CG1 4.48Å; E39-I41 PolarHBondContact O-N 2.87Å
40	T	38.2	Very low	44.3	Very low	119 Å²	119	124.6 Å²	124.6	73%	0.73	63%	0.627	S	S	*	*			trans	-70.3	92.9	164.1	-2.2	0	0	0	0	107.4	R38 E42	R38-T40 PolarHBondContact O-N 3.5Å; T40-E42 PolarHBondContact O-N 3Å; T40-E42 VanDerWaalsContact O-N 3.14Å
41	I	45.6	Very low	43.8	Very low	103 Å²	103	129.8 Å²	129.8	53%	0.528	65%	0.646	S	S	.	*			trans	-73.1	100.8	172.8	-58.2	171	0	0	0	107	E39 P49	E39-I41 VanDerWaalsContact C-N 3.31Å; E39-I41 HydrophobicContact CB-CG1 4.48Å; E39-I41 PolarHBondContact O-N 2.87Å; I41-P49 HydrophobicContact CG2-CB 3.46Å; I41-P49 VanDerWaalsContact CG2-CB 3.46Å
42	E	50	Low	43.8	Very low	128 Å²	128	128 Å²	128	60%	0.598	64%	0.64	S	S	*	*	E	Extended strand (participates in β ladder)	trans	-77.3	134.8	166.4	-70.8	-174.9	168.3	0	0	108.7	T40 L50	T40-E42 PolarHBondContact O-N 3Å; T40-E42 VanDerWaalsContact O-N 3.14Å; E42-L50 WeakPolarHBondContact O-CB 3.39Å; E42-L50 PolarHBondContact O-N 3.45Å
43	L	47.8	Very low	44.1	Very low	118 Å²	118	127.8 Å²	127.8	62%	0.618	65%	0.648	S	S	*	*	E	Extended strand (participates in β ladder)	trans	-94.1	136.6	177.1	-66.3	162.8	0	0	0	108.6	G47 K48	L43-G47 WeakPolarHBondContact CD2-O 3.4Å; L43-K48 WeakPolarHBondContact CA-O 3.39Å
44	T	54.5	Low	44.2	Very low	59 Å²	59	124.9 Å²	124.9	36%	0.362	64%	0.637	S	S	.	*	P	Polyproline II helix	trans	-61.4	165	165.4	18.9	0	0	0	0	111.1	D46 G47 K48 L50	T44-D46 PolarHBondContact O-N 2.93Å; T44-G47 PolarHBondContact O-N 2.92Å; T44-K48 PolarHBondContact N-O 3.06Å; T44-K48 WeakPolarHBondContact OG1-CB 3.41Å; T44-K48 PolarHBondContact OG1-N 3.32Å; T44-K48 PolarHBondContact OG1-O 3.32Å; T44-K48 VanDerWaalsContact OG1-O 3.06Å; T44-L50 HydrophobicContact CG2-CD1 3.65Å
45	E	50.9	Low	44.8	Very low	208 Å²	208	120.7 Å²	120.7	97%	0.972	62%	0.619	S	S	*	*	T	Hydrogen-bonded Turn	trans	-52.3	-27	171.9	-80.1	-175.9	144.7	0	0	112.5
46	D	51.5	Low	45.5	Very low	143 Å²	143	123.7 Å²	123.7	77%	0.765	63%	0.63	S	S	*	*	T	Hydrogen-bonded Turn	trans	-87.2	6.5	175	-56.7	-40.2	0	0	0	114.8	T44 K48	T44-D46 PolarHBondContact O-N 2.93Å; D46-K48 PolarHBondContact O-N 3.03Å
47	G	44.8	Very low	46.3	Very low	47 Å²	47	121.1 Å²	121.1	49%	0.485	63%	0.628	S	S	.	*			trans	74.2	19.5	176.7	0	0	0	0	0	115.8	L43 T44	L43-G47 WeakPolarHBondContact CD2-O 3.4Å; T44-G47 PolarHBondContact O-N 2.92Å
48	K	47.6	Very low	47.6	Very low	145 Å²	145	119.3 Å²	119.3	63%	0.63	62%	0.618	S	S	*	*			trans	-88.8	138	174.6	-66.6	178.3	-179.6	169.8	0	111	L43 T44 D46 L50	L43-K48 WeakPolarHBondContact CA-O 3.39Å; T44-K48 PolarHBondContact N-O 3.06Å; T44-K48 WeakPolarHBondContact OG1-CB 3.41Å; T44-K48 PolarHBondContact OG1-N 3.32Å; T44-K48 PolarHBondContact OG1-O 3.32Å; T44-K48 VanDerWaalsContact OG1-O 3.06Å; D46-K48 PolarHBondContact O-N 3.03Å; K48-L50 PolarHBondContact O-N 3.04Å
49	P	43.6	Very low	48.6	Very low	93 Å²	93	116 Å²	116	60%	0.604	62%	0.617	S	S	*	*	E	Extended strand (participates in β ladder)	trans	-67.6	122.6	176.7	27.3	-32.6	0	0	0	109.9	I41	I41-P49 HydrophobicContact CG2-CB 3.46Å; I41-P49 VanDerWaalsContact CG2-CB 3.46Å
50	L	47.5	Very low	49.6	Very low	89 Å²	89	113.3 Å²	113.3	47%	0.466	61%	0.612	S	S	.	*	E	Extended strand (participates in β ladder)	trans	-90.2	115.5	170.8	-132.9	111.7	0	0	0	108.2	E42 T44 K48 V52	E42-L50 WeakPolarHBondContact O-CB 3.39Å; E42-L50 PolarHBondContact O-N 3.45Å; T44-L50 HydrophobicContact CG2-CD1 3.65Å; K48-L50 PolarHBondContact O-N 3.04Å; L50-V52 VanDerWaalsContact C-N 3.32Å; L50-V52 HydrophobicContact CD2-CG2 4.4Å; L50-V52 PolarHBondContact O-N 2.8Å
51	E	42.7	Very low	50.6	Low	194 Å²	194	111.3 Å²	111.3	91%	0.907	60%	0.597	S	S	*	*			trans	-69.2	92.3	168.2	-74.2	-175.7	175.3	0	0	108.4	P53	E51-P53 WeakPolarHBondContact O-CD 3.4Å
52	V	48.8	Very low	51.3	Low	69 Å²	69	108.3 Å²	108.3	42%	0.418	58%	0.584	S	S	.	*	P	Polyproline II helix	trans	-76.7	119.3	172.5	-175.2	0	0	0	0	107.3	L50 E54	L50-V52 VanDerWaalsContact C-N 3.32Å; L50-V52 HydrophobicContact CD2-CG2 4.4Å; L50-V52 PolarHBondContact O-N 2.8Å; V52-E54 PolarHBondContact O-N 3.09Å
53	P	47.9	Very low	51.9	Low	112 Å²	112	106.8 Å²	106.8	73%	0.727	58%	0.584	S	S	*	*	P	Polyproline II helix	trans	-59	128.8	177.6	21.9	-31.1	0	0	0	109.8	E51 K55	E51-P53 WeakPolarHBondContact O-CD 3.4Å; P53-K55 PolarHBondContact O-N 3.33Å; P53-K55 VanDerWaalsContact O-N 3.07Å
54	E	43.7	Very low	52.8	Low	118 Å²	118	103.9 Å²	103.9	55%	0.551	57%	0.573	S	S	*	*	P	Polyproline II helix	trans	-51.9	117.5	177.1	-81.2	-155.7	98.5	0	0	111.1	T37 V52 K56	T37-E54 VanDerWaalsContact CB-CD 3.46Å; T37-E54 WeakPolarHBondContact CB-OE1 3.49Å; T37-E54 VanDerWaalsContact CG2-CD 3.42Å; T37-E54 WeakPolarHBondContact CG2-OE1 3.25Å; T37-E54 WeakPolarHBondContact CG2-OE2 3.47Å; T37-E54 PolarHBondContact OG1-OE2 2.94Å; V52-E54 PolarHBondContact O-N 3.09Å; E54-K56 PolarHBondContact O-N 3.23Å; E54-K56 VanDerWaalsContact O-N 3.1Å
55	K	51.7	Low	53.5	Low	83 Å²	83	111 Å²	111	36%	0.361	60%	0.599	S	S	.	*			trans	-70.6	107.7	171.5	-70.3	179.1	174.4	-167.9	0	107.5	P53 A57 A269 H271 P272	P53-K55 PolarHBondContact O-N 3.33Å; P53-K55 VanDerWaalsContact O-N 3.07Å; K55-A57 PolarHBondContact O-N 3.42Å; K55-A57 VanDerWaalsContact O-N 3.07Å; K55-A269 WeakPolarHBondContact CE-O 2.8Å; K55-A269 PolarHBondContact NZ-O 3.27Å; K55-A269 VanDerWaalsContact NZ-O 3.15Å; K55-H271 PolarHBondContact NZ-O 2.89Å; K55-P272 HydrophobicContact CB-CB 4.39Å
56	K	52.5	Low	54.4	Low	192 Å²	192	104.5 Å²	104.5	84%	0.835	59%	0.587	S	S	*	*	P	Polyproline II helix	trans	-49.7	120.7	169.9	-73.5	-176.1	178.8	-179.7	0	108.9	E54 P272	E54-K56 PolarHBondContact O-N 3.23Å; E54-K56 VanDerWaalsContact O-N 3.1Å; K56-P272 WeakPolarHBondContact O-CB 3.01Å
57	A	52.2	Low	55.9	Low	87 Å²	87	101.5 Å²	101.5	72%	0.719	57%	0.571	S	S	*	*	P	Polyproline II helix	trans	-55.1	135.6	174.4	0	0	0	0	0	109.1	K55	K55-A57 PolarHBondContact O-N 3.42Å; K55-A57 VanDerWaalsContact O-N 3.07Å
58	P	61.5	Low	57.8	Low	30 Å²	30	101.3 Å²	101.3	20%	0.195	56%	0.561	C	S	.	*	P	Polyproline II helix	trans	-66.9	148.3	-179.4	29.8	-32.9	0	0	0	109.6	C60 P272 T273	P58-C60 PolarHBondContact O-N 2.88Å; P58-P272 HydrophobicContact CB-CG 3.97Å; P58-P272 HydrophobicContact CG-CG 4.03Å; P58-T273 HydrophobicContact CG-CG2 3.37Å
59	L	58.8	Low	59.8	Low	172 Å²	172	95.5 Å²	95.5	90%	0.901	54%	0.536	S	S	*	.	S	Bend	trans	-60.7	-27.6	177.7	-75.2	159.9	0	0	0	112.8	L262	L59-L262 HydrophobicContact CB-CD2 4.36Å
60	C	58.8	Low	62	Low	70 Å²	70	92.4 Å²	92.4	47%	0.473	51%	0.512	S	S	.	.	S	Bend	trans	-153.1	129.6	174.9	-167.3	0	0	0	0	109.3	P58 C62	P58-C60 PolarHBondContact O-N 2.88Å; C60-C62 PolarHBondContact O-N 3.22Å
61	D	59.9	Low	64.1	Low	78 Å²	78	89.4 Å²	89.4	42%	0.417	50%	0.495	S	S	.	.			trans	-93.2	91.8	179.4	-142	-5.7	0	0	0	109.3	T63 R69 T273	D61-T63 PolarHBondContact O-N 3.07Å; D61-R69 IonicContact OD1-CZ 3.77Å; D61-R69 IonicContact OD1-NH2 3.22Å; D61-R69 PolarHBondContact OD1-NH2 3.28Å; D61-T273 WeakPolarHBondContact OD1-CB 3.46Å; D61-T273 WeakPolarHBondContact OD1-CG2 3.42Å; D61-T273 PolarHBondContact OD1-OG1 2.91Å; D61-T273 VanDerWaalsContact OD2-CG2 3.22Å; D61-T273 WeakPolarHBondContact OD2-CG2 3.13Å
62	C	61.1	Low	66.4	Low	39 Å²	39	80.8 Å²	80.8	26%	0.264	45%	0.454	S	S	.	.			trans	-75.6	76.6	176.5	-78.6	0	0	0	0	110.2	C60 C64 R69 V263	C60-C62 PolarHBondContact O-N 3.22Å; C62-C64 VanDerWaalsContact C-N 3.29Å; C62-C64 PolarHBondContact O-N 3.02Å; C62-R69 PolarHBondContact O-NH1 3.03Å; C62-V263 HydrophobicContact CB-CG2 4.22Å
63	T	63.1	Low	68.5	Low	96 Å²	96	77.6 Å²	77.6	59%	0.589	44%	0.435	S	S	*	.			trans	-77.1	81.2	168.1	44	0	0	0	0	109.1	D61 F65	D61-T63 PolarHBondContact O-N 3.07Å; T63-F65 VanDerWaalsContact C-N 3.32Å; T63-F65 PolarHBondContact O-N 3.07Å
64	C	64.8	Low	70.7	Confident	58 Å²	58	72.2 Å²	72.2	39%	0.392	40%	0.4	S	S	.	.			trans	-67.6	88.3	173.8	-68.3	0	0	0	0	110.3	C62 G66 L67 I72	C62-C64 VanDerWaalsContact C-N 3.29Å; C62-C64 PolarHBondContact O-N 3.02Å; C64-G66 PolarHBondContact O-N 3.1Å; C64-G66 VanDerWaalsContact O-N 3.12Å; C64-L67 WeakPolarHBondContact O-CB 3.2Å; C64-L67 WeakPolarHBondContact O-CG 3.26Å; C64-L67 PolarHBondContact O-N 3.24Å; C64-L67 VanDerWaalsContact O-N 3.1Å; C64-I72 HydrophobicContact CB-CD1 4.4Å
65	F	71.1	Confident	73.2	Confident	209 Å²	209	70.5 Å²	70.5	92%	0.917	39%	0.394	S	S	*	.	T	Hydrogen-bonded Turn	trans	56	27.5	173.3	-59	-82.4	0	0	0	115.7	T63 L67	T63-F65 VanDerWaalsContact C-N 3.32Å; T63-F65 PolarHBondContact O-N 3.07Å; F65-L67 VanDerWaalsContact C-N 3.27Å; F65-L67 PolarHBondContact O-N 3.14Å
66	G	69.9	Low	75.2	Confident	70 Å²	70	67.8 Å²	67.8	72%	0.722	38%	0.383	S	S	*	.	T	Hydrogen-bonded Turn	trans	71.9	16.5	-178.8	0	0	0	0	0	114.6	C64	C64-G66 PolarHBondContact O-N 3.1Å; C64-G66 VanDerWaalsContact O-N 3.12Å
67	L	81.8	Confident	77.3	Confident	80 Å²	80	58.7 Å²	58.7	42%	0.419	34%	0.343	S	S	.	.			trans	-62.7	140.1	172.9	-75.4	165.5	0	0	0	111	C64 F65 I72	C64-L67 WeakPolarHBondContact O-CB 3.2Å; C64-L67 WeakPolarHBondContact O-CG 3.26Å; C64-L67 PolarHBondContact O-N 3.24Å; C64-L67 VanDerWaalsContact O-N 3.1Å; F65-L67 VanDerWaalsContact C-N 3.27Å; F65-L67 PolarHBondContact O-N 3.14Å; L67-I72 HydrophobicContact CB-CG1 4.16Å
68	P	85.2	Confident	79.4	Confident	44 Å²	44	54.9 Å²	54.9	29%	0.286	31%	0.312	S	S	.	.			trans	-59.7	143.6	175.7	-16.6	27	0	0	0	111.1	R70 Y71 I72 E278	P68-R70 HydrophobicContact CB-CG 4.35Å; P68-R70 PolarHBondContact O-N 3.33Å; P68-Y71 HydrophobicContact CB-CD2 3.97Å; P68-Y71 HydrophobicContact CG-CD2 3.87Å; P68-Y71 HydrophobicContact CG-CE2 4.33Å; P68-Y71 PolarHBondContact O-N 3.48Å; P68-I72 PolarHBondContact O-N 3.25Å; P68-E278 VanDerWaalsContact CB-OE1 3.31Å; P68-E278 WeakPolarHBondContact CB-OE1 3.16Å
69	R	88.3	Confident	81	Confident	23 Å²	23	57.6 Å²	57.6	9%	0.087	33%	0.325	C	S	.	.	H	α-helix	trans	-60	-35	-171	-62.7	-56.8	-173.3	173.7	3.1	112.3	D61 C62 Y71 I72 I73 W205 T273 I274 E278	D61-R69 IonicContact OD1-CZ 3.77Å; D61-R69 IonicContact OD1-NH2 3.22Å; D61-R69 PolarHBondContact OD1-NH2 3.28Å; C62-R69 PolarHBondContact O-NH1 3.03Å; R69-Y71 VanDerWaalsContact C-N 3.32Å; R69-Y71 PolarHBondContact O-N 3.38Å; R69-I72 WeakPolarHBondContact O-CB 3.17Å; R69-I72 PolarHBondContact O-N 2.99Å; R69-I72 VanDerWaalsContact O-N 3.16Å; R69-I73 PolarHBondContact O-N 3.24Å; R69-W205 HydrophobicContact CB-CZ3 4.2Å; R69-T273 PolarHBondContact NE-O 2.88Å; R69-T273 VanDerWaalsContact NE-O 3.12Å; R69-T273 PolarHBondContact NH2-O 2.77Å; R69-T273 PolarHBondContact NH2-OG1 3.09Å; R69-I274 HydrophobicContact CG-CB 4.42Å; R69-I274 HydrophobicContact CG-CG1 4.23Å; R69-E278 PolarHBondContact N-OE1 3.47Å; R69-E278 PolarHBondContact N-OE2 3.06Å
70	R	89.9	Confident	82.8	Confident	27 Å²	27	49.4 Å²	49.4	10%	0.102	28%	0.282	C	S	.	.	H	α-helix	trans	-59.9	-36.3	175.9	67.8	-168.5	-178.4	-95.3	13.8	113.9	P68 A74 W205 E210 L214 E278	P68-R70 HydrophobicContact CB-CG 4.35Å; P68-R70 PolarHBondContact O-N 3.33Å; R70-A74 PolarHBondContact O-N 2.75Å; R70-W205 HydrophobicContact CB-CE3 4.26Å; R70-E210 IonicContact CZ-OE1 3.18Å; R70-E210 IonicContact CZ-OE2 3.67Å; R70-E210 IonicContact NE-OE1 2.95Å; R70-E210 IonicContact NE-OE2 3.21Å; R70-E210 PolarHBondContact NE-OE2 2.9Å; R70-E210 IonicContact NH2-OE1 3.9Å; R70-E210 PolarHBondContact NH2-OE1 3.07Å; R70-E210 IonicContact NH2-OE2 2.53Å; R70-E210 PolarHBondContact NH2-OE2 2.72Å; R70-L214 HydrophobicContact CB-CD1 4.4Å; R70-L214 HydrophobicContact CG-CD1 4.36Å; R70-L214 HydrophobicContact CG-CD2 4.29Å; R70-E278 WeakPolarHBondContact CG-OE1 3.4Å; R70-E278 IonicContact CZ-OE1 2.92Å; R70-E278 PolarHBondContact N-OE1 3.1Å; R70-E278 IonicContact NH1-OE1 3.86Å; R70-E278 PolarHBondContact NH1-OE1 3.4Å
71	Y	91.6	Very high	84.5	Confident	27 Å²	27	46.1 Å²	46.1	11%	0.106	26%	0.26	C	S	.	.	H	α-helix	trans	-73.3	-34.6	176.8	-75.7	-79.8	0	0	0	111.9	P68 R69 I73 A74 I75 E210 R213 L214	P68-Y71 HydrophobicContact CB-CD2 3.97Å; P68-Y71 HydrophobicContact CG-CD2 3.87Å; P68-Y71 HydrophobicContact CG-CE2 4.33Å; P68-Y71 PolarHBondContact O-N 3.48Å; R69-Y71 VanDerWaalsContact C-N 3.32Å; R69-Y71 PolarHBondContact O-N 3.38Å; Y71-I73 VanDerWaalsContact C-N 3.34Å; Y71-A74 WeakPolarHBondContact O-CB 3.33Å; Y71-A74 PolarHBondContact O-N 3.15Å; Y71-I75 WeakPolarHBondContact O-CG1 2.97Å; Y71-I75 PolarHBondContact O-N 2.73Å; Y71-E210 PolarHBondContact OH-OE2 2.78Å; Y71-E210 VanDerWaalsContact OH-OE2 3.13Å; Y71-R213 HydrophobicContact CE1-CG 4.21Å; Y71-R213 VanDerWaalsContact OH-CD 3.29Å; Y71-R213 WeakPolarHBondContact OH-CD 3.22Å; Y71-R213 VanDerWaalsContact OH-CZ 3.32Å; Y71-R213 PolarHBondContact OH-NE 2.86Å; Y71-R213 PolarHBondContact OH-NH1 3.5Å; Y71-L214 HydrophobicContact CD1-CD2 3.72Å; Y71-L214 HydrophobicContact CD2-CD2 4.47Å; Y71-L214 HydrophobicContact CE1-CD2 3.63Å; Y71-L214 HydrophobicContact CE2-CD2 4.4Å; Y71-L214 HydrophobicContact CG-CD2 4.13Å
72	I	92.2	Very high	86.2	Confident	12 Å²	12	43.5 Å²	43.5	6%	0.062	25%	0.247	C	C	.	.	H	α-helix	trans	-62.5	-45.5	174.5	-55.1	178	0	0	0	109.6	C64 L67 P68 R69 A74 I75 M76 V263	C64-I72 HydrophobicContact CB-CD1 4.4Å; L67-I72 HydrophobicContact CB-CG1 4.16Å; P68-I72 PolarHBondContact O-N 3.25Å; R69-I72 WeakPolarHBondContact O-CB 3.17Å; R69-I72 PolarHBondContact O-N 2.99Å; R69-I72 VanDerWaalsContact O-N 3.16Å; I72-A74 VanDerWaalsContact C-N 3.29Å; I72-A74 PolarHBondContact O-N 3.31Å; I72-I75 PolarHBondContact O-N 3.16Å; I72-M76 HydrophobicContact CG2-CG 4.41Å; I72-M76 WeakPolarHBondContact O-CB 3.33Å; I72-M76 VanDerWaalsContact O-CG 3.31Å; I72-M76 WeakPolarHBondContact O-CG 3.34Å; I72-M76 PolarHBondContact O-N 3.19Å; I72-V263 HydrophobicContact CG2-CG1 3.59Å
73	I	92.8	Very high	87.8	Confident	2 Å²	2	42.8 Å²	42.8	1%	0.01	24%	0.24	C	C	.	.	H	α-helix	trans	-61.6	-38.2	175.2	-66	171.2	0	0	0	111.1	R69 Y71 M76 S77 I201 W202 W205 W260	R69-I73 PolarHBondContact O-N 3.24Å; Y71-I73 VanDerWaalsContact C-N 3.34Å; I73-M76 PolarHBondContact O-N 3.05Å; I73-S77 VanDerWaalsContact O-CB 3.29Å; I73-S77 WeakPolarHBondContact O-CB 3.48Å; I73-S77 PolarHBondContact O-N 3.23Å; I73-S77 PolarHBondContact O-OG 3.23Å; I73-I201 HydrophobicContact CG2-CG2 3.96Å; I73-W202 HydrophobicContact CB-CH2 4.45Å; I73-W202 HydrophobicContact CG2-CH2 4Å; I73-W205 HydrophobicContact CD1-CD2 3.58Å; I73-W205 HydrophobicContact CD1-CE3 3.58Å; I73-W205 HydrophobicContact CD1-CG 4.39Å; I73-W205 HydrophobicContact CD1-CH2 3.49Å; I73-W205 VanDerWaalsContact CD1-CH2 3.49Å; I73-W205 HydrophobicContact CD1-CZ2 3.47Å; I73-W205 VanDerWaalsContact CD1-CZ2 3.47Å; I73-W205 HydrophobicContact CD1-CZ3 3.54Å; I73-W260 HydrophobicContact CG2-CH2 4.45Å
74	A	94.5	Very high	89.3	Confident	0 Å²	0	38.2 Å²	38.2	0%	0	21%	0.213	C	C	.	.	H	α-helix	trans	-64.7	-46.1	178.1	0	0	0	0	0	112.1	R70 Y71 I72 S77 G78 W202 L214 T217 S218	R70-A74 PolarHBondContact O-N 2.75Å; Y71-A74 WeakPolarHBondContact O-CB 3.33Å; Y71-A74 PolarHBondContact O-N 3.15Å; I72-A74 VanDerWaalsContact C-N 3.29Å; I72-A74 PolarHBondContact O-N 3.31Å; A74-S77 PolarHBondContact O-N 2.87Å; A74-G78 PolarHBondContact O-N 3.22Å; A74-W202 VanDerWaalsContact CA-CH2 3.47Å; A74-W202 HydrophobicContact CB-CH2 3.55Å; A74-W202 HydrophobicContact CB-CZ2 3.95Å; A74-L214 HydrophobicContact CB-CD2 4.03Å; A74-T217 HydrophobicContact CB-CG2 4.26Å; A74-S218 PolarHBondContact O-OG 2.72Å
75	I	94.8	Very high	90.5	Very high	81 Å²	81	36.2 Å²	36.2	42%	0.415	20%	0.197	S	C	.	.	H	α-helix	trans	-64.7	-44.1	177.1	-66.6	165.8	0	0	0	110.5	Y71 I72 S77 G78 L79 T217	Y71-I75 WeakPolarHBondContact O-CG1 2.97Å; Y71-I75 PolarHBondContact O-N 2.73Å; I72-I75 PolarHBondContact O-N 3.16Å; I75-S77 VanDerWaalsContact C-N 3.32Å; I75-S77 PolarHBondContact O-N 3.27Å; I75-G78 PolarHBondContact O-N 3.19Å; I75-L79 HydrophobicContact CG2-CD1 4.42Å; I75-L79 WeakPolarHBondContact O-CG 3.28Å; I75-L79 PolarHBondContact O-N 3.26Å; I75-T217 HydrophobicContact CG1-CG2 4.39Å
76	M	95.1	Very high	91.4	Very high	27 Å²	27	26.3 Å²	26.3	13%	0.133	15%	0.154	C	C	.	.	H	α-helix	trans	-63.2	-39.1	177.2	-74.8	-60.4	-65.5	0	0	112.1	I72 I73 L79 G80 W256 F259 W260	I72-M76 HydrophobicContact CG2-CG 4.41Å; I72-M76 WeakPolarHBondContact O-CB 3.33Å; I72-M76 VanDerWaalsContact O-CG 3.31Å; I72-M76 WeakPolarHBondContact O-CG 3.34Å; I72-M76 PolarHBondContact O-N 3.19Å; I73-M76 PolarHBondContact O-N 3.05Å; M76-L79 PolarHBondContact O-N 3.09Å; M76-L79 HydrophobicContact SD-CD1 4.27Å; M76-G80 PolarHBondContact O-N 3.47Å; M76-W256 WeakPolarHBondContact O-CZ2 3.24Å; M76-W256 PolarHBondContact O-NE1 3.22Å; M76-F259 HydrophobicContact CE-CB 3.76Å; M76-W260 HydrophobicContact CB-CE3 3.95Å; M76-W260 HydrophobicContact CB-CZ3 3.84Å
77	S	95.8	Very high	92.4	Very high	0 Å²	0	23 Å²	23	0%	0	12%	0.119	C	C	.	.	H	α-helix	trans	-64	-42.1	173.5	-58.3	0	0	0	0	111.1	I73 A74 I75 G80 F81	I73-S77 VanDerWaalsContact O-CB 3.29Å; I73-S77 WeakPolarHBondContact O-CB 3.48Å; I73-S77 PolarHBondContact O-N 3.23Å; I73-S77 PolarHBondContact O-OG 3.23Å; A74-S77 PolarHBondContact O-N 2.87Å; I75-S77 VanDerWaalsContact C-N 3.32Å; I75-S77 PolarHBondContact O-N 3.27Å; S77-G80 PolarHBondContact O-N 3.2Å; S77-F81 WeakPolarHBondContact O-CD2 3.49Å; S77-F81 PolarHBondContact O-N 3.15Å
78	G	96.1	Very high	92.7	Very high	7 Å²	7	21 Å²	21	7%	0.072	11%	0.107	C	C	.	.	H	α-helix	trans	-61.7	-43.1	173.9	0	0	0	0	0	113.3	A74 I75 G80 F81 C82 S218 G221	A74-G78 PolarHBondContact O-N 3.22Å; I75-G78 PolarHBondContact O-N 3.19Å; G78-G80 VanDerWaalsContact C-N 3.31Å; G78-G80 PolarHBondContact O-N 3.41Å; G78-F81 PolarHBondContact O-N 2.97Å; G78-C82 WeakPolarHBondContact O-CB 3.21Å; G78-C82 PolarHBondContact O-N 3.37Å; G78-S218 VanDerWaalsContact CA-O 3.31Å; G78-S218 WeakPolarHBondContact CA-O 3.38Å; G78-G221 VanDerWaalsContact O-CA 3.26Å; G78-G221 WeakPolarHBondContact O-CA 3.42Å
79	L	95.9	Very high	92.7	Very high	87 Å²	87	20.1 Å²	20.1	46%	0.455	10%	0.101	S	C	.	.	H	α-helix	trans	-62.7	-38.8	172.5	-70.6	176.4	0	0	0	111.8	I75 M76 C82 I83	I75-L79 HydrophobicContact CG2-CD1 4.42Å; I75-L79 WeakPolarHBondContact O-CG 3.28Å; I75-L79 PolarHBondContact O-N 3.26Å; M76-L79 PolarHBondContact O-N 3.09Å; M76-L79 HydrophobicContact SD-CD1 4.27Å; L79-C82 WeakPolarHBondContact O-CB 3.43Å; L79-C82 PolarHBondContact O-N 3.33Å; L79-I83 WeakPolarHBondContact O-CG1 3.14Å; L79-I83 PolarHBondContact O-N 3.32Å
80	G	96.3	Very high	92.5	Very high	0 Å²	0	19 Å²	19	0%	0	10%	0.097	C	C	.	.	H	α-helix	trans	-60	-48.9	174.2	0	0	0	0	0	112.3	M76 S77 G78 C82 I83 S84	M76-G80 PolarHBondContact O-N 3.47Å; S77-G80 PolarHBondContact O-N 3.2Å; G78-G80 VanDerWaalsContact C-N 3.31Å; G78-G80 PolarHBondContact O-N 3.41Å; G80-C82 VanDerWaalsContact C-N 3.32Å; G80-C82 PolarHBondContact O-N 2.9Å; G80-I83 PolarHBondContact O-N 3.43Å; G80-S84 WeakPolarHBondContact O-CB 3.43Å; G80-S84 PolarHBondContact O-N 3.18Å
81	F	95.7	Very high	92.4	Very high	1 Å²	1	17.8 Å²	17.8	0%	0.004	9%	0.092	C	C	.	.	H	α-helix	trans	-61.6	-38.4	173.9	-83.9	-65.2	0	0	0	112.8	S77 G78 S84 F85 F155 T194 Y195 C198 S218 F219 S222	S77-F81 WeakPolarHBondContact O-CD2 3.49Å; S77-F81 PolarHBondContact O-N 3.15Å; G78-F81 PolarHBondContact O-N 2.97Å; F81-S84 PolarHBondContact O-N 3.21Å; F81-F85 HydrophobicContact CD1-CE2 4.35Å; F81-F85 WeakPolarHBondContact O-CB 3.31Å; F81-F85 PolarHBondContact O-N 3.5Å; F81-F155 HydrophobicContact CD2-CE2 4.35Å; F81-F155 HydrophobicContact CD2-CZ 4.21Å; F81-F155 HydrophobicContact CE1-CE2 4.48Å; F81-F155 AromaticContact CE2-CE2 3.85Å; F81-F155 HydrophobicContact CE2-CE2 3.85Å; F81-F155 HydrophobicContact CE2-CZ 4.12Å; F81-F155 AromaticContact CZ-CE2 3.91Å; F81-F155 HydrophobicContact CZ-CE2 3.91Å; F81-T194 HydrophobicContact CD1-CG2 4.09Å; F81-T194 HydrophobicContact CE1-CG2 3.61Å; F81-T194 HydrophobicContact CZ-CG2 4.06Å; F81-Y195 HydrophobicContact CD1-CE2 4.45Å; F81-Y195 HydrophobicContact CE1-CD1 4.25Å; F81-Y195 AromaticContact CE1-CD2 3.92Å; F81-Y195 HydrophobicContact CE1-CD2 3.92Å; F81-Y195 HydrophobicContact CE1-CE1 4.2Å; F81-Y195 AromaticContact CE1-CE2 3.87Å; F81-Y195 HydrophobicContact CE1-CE2 3.87Å; F81-Y195 HydrophobicContact CE1-CG 4.11Å; F81-Y195 HydrophobicContact CZ-CD1 4.31Å; F81-Y195 HydrophobicContact CZ-CE1 4.5Å; F81-Y195 HydrophobicContact CZ-CG 4.37Å; F81-C198 HydrophobicContact CE2-CB 3.81Å; F81-C198 HydrophobicContact CZ-CB 3.81Å; F81-S218 WeakPolarHBondContact CD2-O 3.49Å; F81-F219 HydrophobicContact CE2-CD1 4.11Å; F81-F219 AromaticContact CE2-CE1 3.93Å; F81-F219 HydrophobicContact CE2-CE1 3.93Å; F81-F219 HydrophobicContact CZ-CD1 4.21Å; F81-F219 AromaticContact CZ-CE1 3.84Å; F81-F219 HydrophobicContact CZ-CE1 3.84Å; F81-S222 WeakPolarHBondContact CD1-OG 3.42Å
82	C	95.1	Very high	91.9	Very high	23 Å²	23	17.8 Å²	17.8	16%	0.155	10%	0.1	C	C	.	.	H	α-helix	trans	-59.4	-46.4	176.6	-179.1	0	0	0	0	111.7	G78 L79 G80 G86 G221 G225	G78-C82 WeakPolarHBondContact O-CB 3.21Å; G78-C82 PolarHBondContact O-N 3.37Å; L79-C82 WeakPolarHBondContact O-CB 3.43Å; L79-C82 PolarHBondContact O-N 3.33Å; G80-C82 VanDerWaalsContact C-N 3.32Å; G80-C82 PolarHBondContact O-N 2.9Å; C82-G86 PolarHBondContact O-N 2.94Å; C82-G221 WeakPolarHBondContact CA-O 3.44Å; C82-G221 WeakPolarHBondContact CB-O 3.04Å; C82-G221 PolarHBondContact N-O 3.17Å; C82-G225 VanDerWaalsContact O-CA 3.3Å; C82-G225 WeakPolarHBondContact O-CA 3.38Å; C82-G225 WeakPolarHBondContact SG-CA 3.21Å
83	I	94.7	Very high	91.5	Very high	24 Å²	24	19.1 Å²	19.1	12%	0.123	11%	0.109	C	C	.	.	H	α-helix	trans	-65	-46.3	176.3	-65.4	166.2	0	0	0	110.7	L79 G80 G86 I87 W256	L79-I83 WeakPolarHBondContact O-CG1 3.14Å; L79-I83 PolarHBondContact O-N 3.32Å; G80-I83 PolarHBondContact O-N 3.43Å; I83-G86 PolarHBondContact O-N 3.43Å; I83-I87 HydrophobicContact CG2-CD1 4.22Å; I83-I87 WeakPolarHBondContact O-CG1 3.22Å; I83-I87 PolarHBondContact O-N 3.31Å; I83-W256 HydrophobicContact CD1-CB 3.52Å; I83-W256 HydrophobicContact CD1-CD2 4.47Å; I83-W256 HydrophobicContact CD1-CG 3.67Å
84	S	93.4	Very high	91.2	Very high	1 Å²	1	19 Å²	19	1%	0.007	11%	0.109	C	C	.	.	H	α-helix	trans	-58.7	-52	-179.2	-160.2	0	0	0	0	112.1	G80 F81 G86 I87 R88 E191	G80-S84 WeakPolarHBondContact O-CB 3.43Å; G80-S84 PolarHBondContact O-N 3.18Å; F81-S84 PolarHBondContact O-N 3.21Å; S84-G86 VanDerWaalsContact C-N 3.29Å; S84-G86 PolarHBondContact O-N 2.76Å; S84-I87 WeakPolarHBondContact O-CB 3.38Å; S84-I87 PolarHBondContact O-N 3.11Å; S84-R88 PolarHBondContact O-N 2.97Å; S84-R88 VanDerWaalsContact O-N 3.15Å; S84-E191 VanDerWaalsContact OG-CG 3.27Å; S84-E191 WeakPolarHBondContact OG-CG 3.27Å; S84-E191 PolarHBondContact OG-OE1 3.47Å
85	F	89.9	Confident	90.7	Very high	16 Å²	16	19.3 Å²	19.3	7%	0.07	11%	0.11	C	C	.	.	H	α-helix	trans	-66.5	-31.8	175.9	-90.1	-103.4	0	0	0	112.5	F81 I87 R88 C89 Y195 S222	F81-F85 HydrophobicContact CD1-CE2 4.35Å; F81-F85 WeakPolarHBondContact O-CB 3.31Å; F81-F85 PolarHBondContact O-N 3.5Å; F85-I87 VanDerWaalsContact C-N 3.31Å; F85-I87 PolarHBondContact O-N 2.83Å; F85-R88 WeakPolarHBondContact O-CB 3.34Å; F85-R88 PolarHBondContact O-N 2.86Å; F85-R88 VanDerWaalsContact O-N 3.11Å; F85-C89 PolarHBondContact O-N 3.26Å; F85-Y195 AromaticContact CE2-CE2 3.72Å; F85-Y195 HydrophobicContact CE2-CE2 3.72Å; F85-Y195 AromaticContact CE2-CZ 3.88Å; F85-Y195 WeakPolarHBondContact CE2-OH 3.35Å; F85-Y195 AromaticContact CZ-CE2 3.94Å; F85-Y195 HydrophobicContact CZ-CE2 3.94Å; F85-Y195 AromaticContact CZ-CZ 3.97Å; F85-Y195 WeakPolarHBondContact CZ-OH 3.37Å; F85-S222 WeakPolarHBondContact CB-O 3.2Å; F85-S222 WeakPolarHBondContact CD1-O 3.45Å; F85-S222 VanDerWaalsContact CE2-CB 3.44Å; F85-S222 VanDerWaalsContact CE2-OG 3.24Å; F85-S222 WeakPolarHBondContact CE2-OG 3.27Å; F85-S222 WeakPolarHBondContact CG-O 3.47Å
86	G	90.7	Very high	90.1	Very high	0 Å²	0	19.5 Å²	19.5	0%	0	12%	0.115	C	C	.	.	H	α-helix	trans	-60.9	-40.5	172.4	0	0	0	0	0	112.6	C82 I83 S84 R88 C89 N90	C82-G86 PolarHBondContact O-N 2.94Å; I83-G86 PolarHBondContact O-N 3.43Å; S84-G86 VanDerWaalsContact C-N 3.29Å; S84-G86 PolarHBondContact O-N 2.76Å; G86-R88 VanDerWaalsContact C-N 3.3Å; G86-R88 PolarHBondContact O-N 3.38Å; G86-C89 PolarHBondContact O-N 3.43Å; G86-N90 WeakPolarHBondContact O-CB 3.1Å; G86-N90 PolarHBondContact O-N 3.41Å
87	I	91.5	Very high	89.5	Confident	0 Å²	0	18.7 Å²	18.7	0%	0	11%	0.111	C	C	.	.	H	α-helix	trans	-64.4	-33.9	172.8	-69.9	167.8	0	0	0	111.7	I83 S84 F85 N90 T162 S163 N166 R184 Y249	I83-I87 HydrophobicContact CG2-CD1 4.22Å; I83-I87 WeakPolarHBondContact O-CG1 3.22Å; I83-I87 PolarHBondContact O-N 3.31Å; S84-I87 WeakPolarHBondContact O-CB 3.38Å; S84-I87 PolarHBondContact O-N 3.11Å; F85-I87 VanDerWaalsContact C-N 3.31Å; F85-I87 PolarHBondContact O-N 2.83Å; I87-N90 PolarHBondContact O-OD1 3.15Å; I87-T162 HydrophobicContact CD1-CG2 4.14Å; I87-S163 WeakPolarHBondContact CD1-OG 3.38Å; I87-N166 HydrophobicContact CD1-CB 4.38Å; I87-N166 HydrophobicContact CG2-CB 4.11Å; I87-N166 WeakPolarHBondContact CG2-OD1 3.46Å; I87-R184 PolarHBondContact O-NH2 2.84Å; I87-Y249 HydrophobicContact CG1-CD1 4.27Å; I87-Y249 HydrophobicContact CG1-CG 4.44Å
88	R	88.1	Confident	89	Confident	40 Å²	40	18.8 Å²	18.8	15%	0.151	11%	0.111	C	C	.	.	H	α-helix	trans	-65.7	-44.7	175.6	-168.4	177.7	-65.9	115.3	2	111.9	S84 F85 G86 F131 E191	S84-R88 PolarHBondContact O-N 2.97Å; S84-R88 VanDerWaalsContact O-N 3.15Å; F85-R88 WeakPolarHBondContact O-CB 3.34Å; F85-R88 PolarHBondContact O-N 2.86Å; F85-R88 VanDerWaalsContact O-N 3.11Å; G86-R88 VanDerWaalsContact C-N 3.3Å; G86-R88 PolarHBondContact O-N 3.38Å; R88-F131 HydrophobicContact CG-CE1 4.42Å; R88-E191 IonicContact CZ-OE1 3.34Å; R88-E191 IonicContact NH1-OE1 2.8Å; R88-E191 VanDerWaalsContact NH2-CD 3.27Å; R88-E191 IonicContact NH2-OE1 3.2Å; R88-E191 PolarHBondContact NH2-OE1 3.3Å; R88-E191 IonicContact NH2-OE2 3.81Å
89	C	84.5	Confident	88.5	Confident	24 Å²	24	19.7 Å²	19.7	16%	0.162	12%	0.116	C	C	.	.	H	α-helix	trans	-80.1	-22.5	-176.8	-64.8	0	0	0	0	114	F85 G86 L91 G92 A229	F85-C89 PolarHBondContact O-N 3.26Å; G86-C89 PolarHBondContact O-N 3.43Å; C89-L91 VanDerWaalsContact C-N 3.32Å; C89-L91 PolarHBondContact O-N 3.04Å; C89-G92 PolarHBondContact O-N 3.23Å; C89-A229 HydrophobicContact CB-CB 4.06Å
90	N	85.2	Confident	87.7	Confident	0 Å²	0	19.7 Å²	19.7	0%	0	12%	0.116	C	C	.	.	H	α-helix	trans	-59.4	-38.3	-172.5	71.7	9.3	0	0	0	114.3	G86 I87 G92 V93 A94 N166 R184 V245 Y249	G86-N90 WeakPolarHBondContact O-CB 3.1Å; G86-N90 PolarHBondContact O-N 3.41Å; I87-N90 PolarHBondContact O-OD1 3.15Å; N90-G92 PolarHBondContact O-N 2.86Å; N90-V93 PolarHBondContact O-N 3.28Å; N90-A94 PolarHBondContact O-N 3.15Å; N90-N166 PolarHBondContact ND2-ND2 3.09Å; N90-N166 PolarHBondContact ND2-OD1 2.81Å; N90-R184 PolarHBondContact OD1-NH2 3.46Å; N90-V245 HydrophobicContact CB-CG1 3.67Å; N90-Y249 HydrophobicContact CB-CD2 4.4Å
91	L	86.4	Confident	86.7	Confident	2 Å²	2	25.4 Å²	25.4	1%	0.01	15%	0.146	C	C	.	.	H	α-helix	trans	-72.4	-33.6	-171.6	172.8	73.3	0	0	0	111.4	C89 V93 A94 I95 I127 R184 F246	C89-L91 VanDerWaalsContact C-N 3.32Å; C89-L91 PolarHBondContact O-N 3.04Å; L91-V93 VanDerWaalsContact C-N 3.26Å; L91-V93 PolarHBondContact O-N 3.24Å; L91-A94 PolarHBondContact O-N 2.95Å; L91-I95 HydrophobicContact CD1-CD1 3.72Å; L91-I95 HydrophobicContact CD1-CG1 3.66Å; L91-I95 HydrophobicContact CD2-CD1 3.94Å; L91-I95 HydrophobicContact CG-CD1 3.55Å; L91-I95 HydrophobicContact CG-CG1 3.92Å; L91-I95 WeakPolarHBondContact O-CB 3.44Å; L91-I95 VanDerWaalsContact O-CG1 3.29Å; L91-I95 WeakPolarHBondContact O-CG1 3.4Å; L91-I95 PolarHBondContact O-N 3.39Å; L91-I127 HydrophobicContact CD2-CG2 3.76Å; L91-R184 HydrophobicContact CD2-CG 4.4Å; L91-R184 VanDerWaalsContact CD2-CZ 3.48Å; L91-F246 HydrophobicContact CB-CE1 4.44Å; L91-F246 HydrophobicContact CD1-CE1 4.13Å; L91-F246 HydrophobicContact CD1-CZ 3.79Å
92	G	82.3	Confident	85.2	Confident	27 Å²	27	26.4 Å²	26.4	28%	0.278	15%	0.154	S	C	.	.	H	α-helix	trans	-60.3	-39.8	176.7	0	0	0	0	0	112.3	C89 N90 H128	C89-G92 PolarHBondContact O-N 3.23Å; N90-G92 PolarHBondContact O-N 2.86Å; G92-H128 WeakPolarHBondContact CA-CE1 3.47Å
93	V	82.3	Confident	83.7	Confident	40 Å²	40	28.5 Å²	28.5	24%	0.242	17%	0.166	C	C	.	.	H	α-helix	trans	-73.1	-42.5	176.1	-175	0	0	0	0	111.1	N90 L91 I95 V96 A233	N90-V93 PolarHBondContact O-N 3.28Å; L91-V93 VanDerWaalsContact C-N 3.26Å; L91-V93 PolarHBondContact O-N 3.24Å; V93-I95 PolarHBondContact O-N 3.16Å; V93-V96 PolarHBondContact O-N 3.11Å; V93-A233 HydrophobicContact CB-CB 3.82Å; V93-A233 HydrophobicContact CG1-CB 3.87Å; V93-A233 HydrophobicContact CG2-CB 4.14Å
94	A	86.4	Confident	82.3	Confident	0 Å²	0	28.6 Å²	28.6	0%	0	17%	0.166	C	C	.	.	H	α-helix	trans	-65.1	-38.4	-179.6	0	0	0	0	0	112.9	N90 L91 V96 D97 M98 F246	N90-A94 PolarHBondContact O-N 3.15Å; L91-A94 PolarHBondContact O-N 2.95Å; A94-V96 PolarHBondContact O-N 2.53Å; A94-D97 PolarHBondContact O-N 2.91Å; A94-D97 VanDerWaalsContact O-N 3.16Å; A94-M98 VanDerWaalsContact O-CG 3.29Å; A94-M98 WeakPolarHBondContact O-CG 3.38Å; A94-M98 PolarHBondContact O-N 3.17Å; A94-M98 VanDerWaalsContact O-N 3.15Å; A94-F246 HydrophobicContact CB-CE2 3.72Å; A94-F246 HydrophobicContact CB-CZ 3.71Å
95	I	84.9	Confident	80.9	Confident	5 Å²	5	34.2 Å²	34.2	3%	0.026	19%	0.192	C	C	.	.	H	α-helix	trans	-59.8	-36.1	-179.6	-78.6	175.5	0	0	0	111.2	L91 V93 D97 M98 V99 V124 I127	L91-I95 HydrophobicContact CD1-CD1 3.72Å; L91-I95 HydrophobicContact CD1-CG1 3.66Å; L91-I95 HydrophobicContact CD2-CD1 3.94Å; L91-I95 HydrophobicContact CG-CD1 3.55Å; L91-I95 HydrophobicContact CG-CG1 3.92Å; L91-I95 WeakPolarHBondContact O-CB 3.44Å; L91-I95 VanDerWaalsContact O-CG1 3.29Å; L91-I95 WeakPolarHBondContact O-CG1 3.4Å; L91-I95 PolarHBondContact O-N 3.39Å; V93-I95 PolarHBondContact O-N 3.16Å; I95-D97 VanDerWaalsContact C-N 3.26Å; I95-D97 PolarHBondContact O-N 3.22Å; I95-M98 HydrophobicContact CG1-SD 4.31Å; I95-M98 WeakPolarHBondContact O-CB 3.2Å; I95-M98 PolarHBondContact O-N 3.32Å; I95-V99 HydrophobicContact CG2-CG1 4.22Å; I95-V99 HydrophobicContact CG2-CG2 4.09Å; I95-V99 WeakPolarHBondContact O-CG2 2.96Å; I95-V99 PolarHBondContact O-N 3Å; I95-V124 HydrophobicContact CD1-CG1 4.38Å; I95-V124 HydrophobicContact CG2-CG1 3.73Å; I95-V124 HydrophobicContact CG2-CG2 4.03Å; I95-I127 HydrophobicContact CD1-CG2 4.34Å
96	V	81.8	Confident	79.6	Confident	86 Å²	86	41.6 Å²	41.6	52%	0.521	22%	0.22	S	C	.	.	H	α-helix	trans	-56.9	-40	179	177.4	0	0	0	0	111.5	V93 A94 N100	V93-V96 PolarHBondContact O-N 3.11Å; A94-V96 PolarHBondContact O-N 2.53Å; V96-N100 VanDerWaalsContact O-CB 3.26Å; V96-N100 WeakPolarHBondContact O-CB 3.35Å; V96-N100 PolarHBondContact O-N 3.14Å; V96-N100 PolarHBondContact O-ND2 3.39Å
97	D	82.6	Confident	78.1	Confident	10 Å²	10	45.7 Å²	45.7	5%	0.053	26%	0.262	C	S	.	.	H	α-helix	trans	-78.2	-26.1	174.3	-175.2	70.6	0	0	0	113.2	A94 I95 S102 K116 V237 W242	A94-D97 PolarHBondContact O-N 2.91Å; A94-D97 VanDerWaalsContact O-N 3.16Å; I95-D97 VanDerWaalsContact C-N 3.26Å; I95-D97 PolarHBondContact O-N 3.22Å; D97-S102 WeakPolarHBondContact OD1-CB 3.38Å; D97-S102 PolarHBondContact OD1-OG 3.09Å; D97-K116 IonicContact OD2-NZ 2.94Å; D97-K116 PolarHBondContact OD2-NZ 3.23Å; D97-V237 HydrophobicContact CB-CG1 3.51Å; D97-W242 HydrophobicContact CB-CB 4.4Å
98	M	85.3	Confident	76.7	Confident	1 Å²	1	49.5 Å²	49.5	1%	0.005	30%	0.301	C	S	.	.	H	α-helix	trans	-71.5	-40.6	-179.2	-71.2	172.5	73.6	0	0	112.4	A94 I95 K116 F117 W119 A173 W242	A94-M98 VanDerWaalsContact O-CG 3.29Å; A94-M98 WeakPolarHBondContact O-CG 3.38Å; A94-M98 PolarHBondContact O-N 3.17Å; A94-M98 VanDerWaalsContact O-N 3.15Å; I95-M98 HydrophobicContact CG1-SD 4.31Å; I95-M98 WeakPolarHBondContact O-CB 3.2Å; I95-M98 PolarHBondContact O-N 3.32Å; M98-K116 PolarHBondContact O-N 3.36Å; M98-F117 HydrophobicContact CB-CD2 3.83Å; M98-F117 HydrophobicContact CB-CE2 4.34Å; M98-F117 HydrophobicContact CE-CD2 3.78Å; M98-F117 HydrophobicContact CE-CE2 3.58Å; M98-F117 HydrophobicContact CE-CZ 4.4Å; M98-F117 HydrophobicContact CG-CD2 4.2Å; M98-F117 HydrophobicContact CG-CE2 4.21Å; M98-F117 PolarHBondContact O-N 3.06Å; M98-W119 HydrophobicContact CE-CH2 3.38Å; M98-W119 HydrophobicContact CE-CZ2 4.37Å; M98-W119 HydrophobicContact CE-CZ3 3.58Å; M98-A173 HydrophobicContact CE-CB 3.68Å; M98-W242 HydrophobicContact CE-CE3 4.14Å; M98-W242 HydrophobicContact CE-CH2 4.45Å; M98-W242 HydrophobicContact CE-CZ3 3.98Å; M98-W242 HydrophobicContact CG-CB 4.16Å; M98-W242 HydrophobicContact CG-CD2 3.89Å; M98-W242 HydrophobicContact CG-CE3 3.99Å; M98-W242 HydrophobicContact CG-CG 3.95Å; M98-W242 HydrophobicContact SD-CD2 4.31Å; M98-W242 HydrophobicContact SD-CE3 3.78Å; M98-W242 HydrophobicContact SD-CZ3 4.2Å
99	V	85.6	Confident	75.5	Confident	27 Å²	27	55 Å²	55	16%	0.164	33%	0.326	C	S	.	.	H	α-helix	trans	-110	-20.3	-170.1	-51.8	0	0	0	0	114.5	I95 A115 W119 V124	I95-V99 HydrophobicContact CG2-CG1 4.22Å; I95-V99 HydrophobicContact CG2-CG2 4.09Å; I95-V99 WeakPolarHBondContact O-CG2 2.96Å; I95-V99 PolarHBondContact O-N 3Å; V99-A115 WeakPolarHBondContact O-CB 3.27Å; V99-W119 HydrophobicContact CG1-CB 3.88Å; V99-W119 HydrophobicContact CG1-CD2 4.2Å; V99-W119 HydrophobicContact CG1-CE3 3.76Å; V99-W119 HydrophobicContact CG1-CG 4.3Å; V99-V124 HydrophobicContact CG1-CG2 4.09Å; V99-V124 HydrophobicContact CG2-CG2 4.48Å
100	N	79.9	Confident	74.8	Confident	87 Å²	87	58.1 Å²	58.1	47%	0.465	35%	0.345	S	S	.	.	S	Bend	trans	-102.2	157.1	178.4	-58.5	-55.2	0	0	0	111.8	V96 S102	V96-N100 VanDerWaalsContact O-CB 3.26Å; V96-N100 WeakPolarHBondContact O-CB 3.35Å; V96-N100 PolarHBondContact O-N 3.14Å; V96-N100 PolarHBondContact O-ND2 3.39Å; N100-S102 PolarHBondContact O-N 3.17Å; N100-S102 VanDerWaalsContact O-N 3.13Å
101	N	74.5	Confident	74.2	Confident	119 Å²	119	62.2 Å²	62.2	64%	0.636	37%	0.366	S	S	*	.			trans	-71	105.7	170.1	-65.4	-31.6	0	0	0	109.1	E113 K114 A115	N101-E113 CarbonylContact C-O 3.53Å; N101-E113 WeakPolarHBondContact CA-O 3.03Å; N101-K114 WeakPolarHBondContact OD1-CA 3.47Å; N101-A115 PolarHBondContact OD1-N 3.17Å
102	S	64	Low	73.4	Confident	23 Å²	23	70.1 Å²	70.1	16%	0.161	40%	0.4	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-90.1	145.2	-179.2	63	0	0	0	0	111.3	D97 N100 K112 E113	D97-S102 WeakPolarHBondContact OD1-CB 3.38Å; D97-S102 PolarHBondContact OD1-OG 3.09Å; N100-S102 PolarHBondContact O-N 3.17Å; N100-S102 VanDerWaalsContact O-N 3.13Å; S102-K112 CarbonylContact O-C 3.58Å; S102-K112 WeakPolarHBondContact O-CA 3.49Å; S102-E113 PolarHBondContact N-O 3.2Å; S102-E113 PolarHBondContact O-N 3.48Å
103	T	64.1	Low	72.8	Confident	67 Å²	67	71.9 Å²	71.9	41%	0.411	40%	0.401	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-107.8	105.7	176.9	-49.7	0	0	0	0	108.1	V110 K112	T103-V110 HydrophobicContact CG2-CB 4.47Å; T103-V110 HydrophobicContact CG2-CG1 3.12Å; T103-K112 HydrophobicContact CG2-CG 4.18Å
104	I	64.4	Low	72.4	Confident	25 Å²	25	78.6 Å²	78.6	13%	0.128	43%	0.427	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-98.3	129.3	-176.6	-53.5	179.1	0	0	0	108.9	R106 I111 E113	I104-R106 PolarHBondContact O-N 3.1Å; I104-I111 PolarHBondContact N-O 2.95Å; I104-I111 PolarHBondContact O-N 3.28Å; I104-E113 VanDerWaalsContact CD1-CD 3.47Å; I104-E113 HydrophobicContact CD1-CG 3.95Å
105	H	64.7	Low	72	Confident	120 Å²	120	79.9 Å²	79.9	56%	0.556	44%	0.437	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-90.3	94.6	174.1	-66.9	-101.8	0	0	0	109
106	R	61.4	Low	71.9	Confident	170 Å²	170	83.4 Å²	83.4	64%	0.642	45%	0.452	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-109.2	115	176.2	-118.6	-179.9	-177.2	174.3	1.9	109.4	I104 G108 K109 I111	I104-R106 PolarHBondContact O-N 3.1Å; R106-G108 PolarHBondContact O-N 3.38Å; R106-K109 PolarHBondContact N-O 3.03Å; R106-K109 VanDerWaalsContact N-O 3.14Å; R106-K109 PolarHBondContact O-N 2.94Å; R106-K109 VanDerWaalsContact O-N 3.17Å; R106-I111 HydrophobicContact CB-CD1 4.38Å
107	G	60.5	Low	72.1	Confident	87 Å²	87	80.8 Å²	80.8	90%	0.897	43%	0.434	S	S	*	.	T	Hydrogen-bonded Turn	trans	59.3	38.4	174.8	0	0	0	0	0	114.7	K109	G107-K109 VanDerWaalsContact C-N 3.27Å; G107-K109 PolarHBondContact O-N 2.7Å
108	G	62.5	Low	72.3	Confident	79 Å²	79	87.9 Å²	87.9	81%	0.814	47%	0.472	S	S	*	.	T	Hydrogen-bonded Turn	trans	78.7	-0.3	-179.6	0	0	0	0	0	115.5	R106	R106-G108 PolarHBondContact O-N 3.38Å
109	K	62.1	Low	72.5	Confident	155 Å²	155	89.3 Å²	89.3	67%	0.674	48%	0.477	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-103.9	135.1	172.6	-70.3	-178.1	179.3	177.6	0	111.1	R106 G107 I111	R106-K109 PolarHBondContact N-O 3.03Å; R106-K109 VanDerWaalsContact N-O 3.14Å; R106-K109 PolarHBondContact O-N 2.94Å; R106-K109 VanDerWaalsContact O-N 3.17Å; G107-K109 VanDerWaalsContact C-N 3.27Å; G107-K109 PolarHBondContact O-N 2.7Å; K109-I111 PolarHBondContact O-N 3.46Å
110	V	69.1	Low	72.6	Confident	91 Å²	91	91.4 Å²	91.4	55%	0.552	49%	0.488	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-85.5	102.1	176.5	-177.9	0	0	0	0	107.8	T103	T103-V110 HydrophobicContact CG2-CB 4.47Å; T103-V110 HydrophobicContact CG2-CG1 3.12Å
111	I	72.6	Confident	72.7	Confident	86 Å²	86	92.9 Å²	92.9	44%	0.441	50%	0.502	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-102.9	120.2	178.4	-56.4	174.4	0	0	0	107.8	I104 R106 K109 E113	I104-I111 PolarHBondContact N-O 2.95Å; I104-I111 PolarHBondContact O-N 3.28Å; R106-I111 HydrophobicContact CB-CD1 4.38Å; K109-I111 PolarHBondContact O-N 3.46Å; I111-E113 PolarHBondContact O-N 3.39Å
112	K	69.4	Low	73.2	Confident	167 Å²	167	94.2 Å²	94.2	73%	0.726	50%	0.504	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-83.9	107	171.3	-69.3	-175	177.6	-177.6	0	108.8	S102 T103	S102-K112 CarbonylContact O-C 3.58Å; S102-K112 WeakPolarHBondContact O-CA 3.49Å; T103-K112 HydrophobicContact CG2-CG 4.18Å
113	E	70.1	Confident	74.3	Confident	64 Å²	64	93.6 Å²	93.6	30%	0.299	50%	0.499	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-77.9	136.4	167.6	-76.1	-163.1	168.7	0	0	109.1	N101 S102 I104 I111 K116	N101-E113 CarbonylContact C-O 3.53Å; N101-E113 WeakPolarHBondContact CA-O 3.03Å; S102-E113 PolarHBondContact N-O 3.2Å; S102-E113 PolarHBondContact O-N 3.48Å; I104-E113 VanDerWaalsContact CD1-CD 3.47Å; I104-E113 HydrophobicContact CD1-CG 3.95Å; I111-E113 PolarHBondContact O-N 3.39Å; E113-K116 VanDerWaalsContact OE2-CE 3.29Å; E113-K116 WeakPolarHBondContact OE2-CE 3.27Å; E113-K116 IonicContact OE2-NZ 3.9Å; E113-K116 PolarHBondContact OE2-NZ 3.37Å
114	K	73.4	Confident	75.4	Confident	182 Å²	182	91.5 Å²	91.5	79%	0.791	49%	0.486	S	S	*	.	P	Polyproline II helix	trans	-74.1	150.7	170.8	-71.1	-175.3	178.7	-178.7	0	109.5	N101 K116	N101-K114 WeakPolarHBondContact OD1-CA 3.47Å; K114-K116 PolarHBondContact O-N 3.47Å
115	A	79.3	Confident	76.3	Confident	26 Å²	26	92.3 Å²	92.3	22%	0.215	50%	0.501	C	S	.	.	P	Polyproline II helix	trans	-46.8	132.5	171.1	0	0	0	0	0	111.1	V99 N101	V99-A115 WeakPolarHBondContact O-CB 3.27Å; N101-A115 PolarHBondContact OD1-N 3.17Å
116	K	82.4	Confident	77.4	Confident	80 Å²	80	90 Å²	90	35%	0.348	49%	0.491	S	S	.	.	S	Bend	trans	-82	-27.8	-176.9	-68.4	173	-178.9	140.2	0	111.5	D97 M98 E113 K114 W242	D97-K116 IonicContact OD2-NZ 2.94Å; D97-K116 PolarHBondContact OD2-NZ 3.23Å; M98-K116 PolarHBondContact O-N 3.36Å; E113-K116 VanDerWaalsContact OE2-CE 3.29Å; E113-K116 WeakPolarHBondContact OE2-CE 3.27Å; E113-K116 IonicContact OE2-NZ 3.9Å; E113-K116 PolarHBondContact OE2-NZ 3.37Å; K114-K116 PolarHBondContact O-N 3.47Å; K116-W242 VanDerWaalsContact CD-CD1 3.45Å
117	F	87.1	Confident	78.8	Confident	31 Å²	31	81.9 Å²	81.9	14%	0.136	46%	0.461	C	S	.	.	S	Bend	trans	-134.8	136.1	179.4	-55.2	-79.1	0	0	0	110.1	M98 W119 A173 R174 W242	M98-F117 HydrophobicContact CB-CD2 3.83Å; M98-F117 HydrophobicContact CB-CE2 4.34Å; M98-F117 HydrophobicContact CE-CD2 3.78Å; M98-F117 HydrophobicContact CE-CE2 3.58Å; M98-F117 HydrophobicContact CE-CZ 4.4Å; M98-F117 HydrophobicContact CG-CD2 4.2Å; M98-F117 HydrophobicContact CG-CE2 4.21Å; M98-F117 PolarHBondContact O-N 3.06Å; F117-W119 VanDerWaalsContact C-N 3.34Å; F117-W119 HydrophobicContact CB-CD2 4.01Å; F117-W119 HydrophobicContact CB-CG 4.21Å; F117-W119 HydrophobicContact CB-CZ2 4.26Å; F117-W119 HydrophobicContact CD1-CZ2 4.23Å; F117-W119 HydrophobicContact CG-CZ2 4.1Å; F117-W119 PolarHBondContact O-N 3.38Å; F117-A173 HydrophobicContact CE1-CB 4.43Å; F117-A173 WeakPolarHBondContact CE1-O 3.47Å; F117-A173 HydrophobicContact CE2-CB 4.39Å; F117-A173 HydrophobicContact CZ-CB 3.96Å; F117-R174 HydrophobicContact CZ-CG 4.5Å; F117-W242 HydrophobicContact CE2-CH2 4.15Å; F117-W242 AromaticContact CE2-CZ2 3.86Å; F117-W242 HydrophobicContact CE2-CZ2 3.86Å; F117-W242 HydrophobicContact CZ-CH2 4.12Å; F117-W242 AromaticContact CZ-CZ2 3.94Å; F117-W242 HydrophobicContact CZ-CZ2 3.94Å
118	N	86.4	Confident	79.8	Confident	159 Å²	159	81.4 Å²	81.4	85%	0.85	44%	0.435	S	S	*	.			trans	-90.5	70.2	174.8	-68.3	-22.2	0	0	0	109.5
119	W	88.7	Confident	80.9	Confident	30 Å²	30	78.8 Å²	78.8	11%	0.114	41%	0.408	C	S	.	.			trans	-97.6	129.6	172.8	-59	-20.1	0	0	0	109.5	M98 V99 F117 T123 V124 I127 A173 V180	M98-W119 HydrophobicContact CE-CH2 3.38Å; M98-W119 HydrophobicContact CE-CZ2 4.37Å; M98-W119 HydrophobicContact CE-CZ3 3.58Å; V99-W119 HydrophobicContact CG1-CB 3.88Å; V99-W119 HydrophobicContact CG1-CD2 4.2Å; V99-W119 HydrophobicContact CG1-CE3 3.76Å; V99-W119 HydrophobicContact CG1-CG 4.3Å; F117-W119 VanDerWaalsContact C-N 3.34Å; F117-W119 HydrophobicContact CB-CD2 4.01Å; F117-W119 HydrophobicContact CB-CG 4.21Å; F117-W119 HydrophobicContact CB-CZ2 4.26Å; F117-W119 HydrophobicContact CD1-CZ2 4.23Å; F117-W119 HydrophobicContact CG-CZ2 4.1Å; F117-W119 PolarHBondContact O-N 3.38Å; W119-T123 HydrophobicContact CB-CG2 4.34Å; W119-T123 HydrophobicContact CG-CG2 4.42Å; W119-V124 HydrophobicContact CB-CG2 4.1Å; W119-I127 HydrophobicContact CD2-CD1 4.19Å; W119-I127 HydrophobicContact CE3-CD1 3.67Å; W119-I127 HydrophobicContact CH2-CD1 4.17Å; W119-I127 HydrophobicContact CZ3-CD1 3.66Å; W119-A173 HydrophobicContact CH2-CB 4.11Å; W119-A173 HydrophobicContact CZ2-CB 4.4Å; W119-V180 HydrophobicContact CH2-CG2 4.08Å; W119-V180 HydrophobicContact CZ2-CG2 4.42Å
120	D	87.4	Confident	82.3	Confident	72 Å²	72	71.4 Å²	71.4	39%	0.385	38%	0.375	S	S	.	.			trans	-72.8	160.2	173.2	63.5	-79.6	0	0	0	111.1	E122 T123 V124	D120-E122 PolarHBondContact O-N 3.25Å; D120-E122 WeakPolarHBondContact OD2-CA 3.39Å; D120-E122 VanDerWaalsContact OD2-CB 3.25Å; D120-E122 WeakPolarHBondContact OD2-CB 3.22Å; D120-E122 PolarHBondContact OD2-N 3.12Å; D120-T123 PolarHBondContact O-N 3.19Å; D120-T123 VanDerWaalsContact OD1-CB 3.29Å; D120-T123 WeakPolarHBondContact OD1-CB 3.33Å; D120-T123 PolarHBondContact OD1-OG1 2.97Å; D120-T123 PolarHBondContact OD2-N 3Å; D120-T123 PolarHBondContact OD2-OG1 3.44Å; D120-V124 PolarHBondContact O-N 3.39Å
121	P	81.9	Confident	83.4	Confident	117 Å²	117	67.2 Å²	67.2	76%	0.76	35%	0.35	S	S	*	.	H	α-helix	trans	-59.2	-30.3	-178.9	-26	35.6	0	0	0	114.6	V124 G125	P121-V124 PolarHBondContact O-N 3.09Å; P121-G125 PolarHBondContact O-N 3.47Å
122	E	85.6	Confident	84.1	Confident	148 Å²	148	65.5 Å²	65.5	69%	0.692	34%	0.339	S	S	*	.	H	α-helix	trans	-69.4	-45	177.9	179.9	178.9	-177.5	0	0	110.2	D120 V124 G125 M126	D120-E122 PolarHBondContact O-N 3.25Å; D120-E122 WeakPolarHBondContact OD2-CA 3.39Å; D120-E122 VanDerWaalsContact OD2-CB 3.25Å; D120-E122 WeakPolarHBondContact OD2-CB 3.22Å; D120-E122 PolarHBondContact OD2-N 3.12Å; E122-V124 PolarHBondContact O-N 3.28Å; E122-G125 PolarHBondContact O-N 2.88Å; E122-M126 HydrophobicContact CG-CE 4.49Å; E122-M126 WeakPolarHBondContact O-CG 3.31Å; E122-M126 PolarHBondContact O-N 2.92Å
123	T	88.3	Confident	85.1	Confident	9 Å²	9	63 Å²	63	6%	0.055	33%	0.325	C	S	.	.	H	α-helix	trans	-59.4	-43.5	172.5	-63.6	0	0	0	0	112.3	W119 D120 G125 M126 I127 Y177	W119-T123 HydrophobicContact CB-CG2 4.34Å; W119-T123 HydrophobicContact CG-CG2 4.42Å; D120-T123 PolarHBondContact O-N 3.19Å; D120-T123 VanDerWaalsContact OD1-CB 3.29Å; D120-T123 WeakPolarHBondContact OD1-CB 3.33Å; D120-T123 PolarHBondContact OD1-OG1 2.97Å; D120-T123 PolarHBondContact OD2-N 3Å; D120-T123 PolarHBondContact OD2-OG1 3.44Å; T123-G125 VanDerWaalsContact C-N 3.33Å; T123-G125 PolarHBondContact O-N 2.87Å; T123-M126 PolarHBondContact O-N 3.22Å; T123-I127 HydrophobicContact CG2-CD1 4.17Å; T123-I127 VanDerWaalsContact O-CG1 3.32Å; T123-I127 WeakPolarHBondContact O-CG1 3.23Å; T123-I127 PolarHBondContact O-N 2.84Å; T123-Y177 HydrophobicContact CG2-CD1 4.33Å; T123-Y177 HydrophobicContact CG2-CD2 3.64Å; T123-Y177 HydrophobicContact CG2-CE2 4.19Å; T123-Y177 HydrophobicContact CG2-CG 3.73Å
124	V	85.9	Confident	86.1	Confident	23 Å²	23	60 Å²	60	14%	0.139	31%	0.312	C	S	.	.	H	α-helix	trans	-60.5	-43.9	175.1	168	0	0	0	0	111.3	I95 V99 W119 D120 P121 E122 M126 I127 H128	I95-V124 HydrophobicContact CD1-CG1 4.38Å; I95-V124 HydrophobicContact CG2-CG1 3.73Å; I95-V124 HydrophobicContact CG2-CG2 4.03Å; V99-V124 HydrophobicContact CG1-CG2 4.09Å; V99-V124 HydrophobicContact CG2-CG2 4.48Å; W119-V124 HydrophobicContact CB-CG2 4.1Å; D120-V124 PolarHBondContact O-N 3.39Å; P121-V124 PolarHBondContact O-N 3.09Å; E122-V124 PolarHBondContact O-N 3.28Å; V124-M126 PolarHBondContact O-N 2.92Å; V124-I127 PolarHBondContact O-N 2.96Å; V124-H128 PolarHBondContact O-CD2 3.5Å; V124-H128 PolarHBondContact O-N 3.38Å
125	G	83.1	Confident	87	Confident	42 Å²	42	51.7 Å²	51.7	43%	0.433	28%	0.276	S	S	.	.	H	α-helix	trans	-59.1	-43.5	174.3	0	0	0	0	0	112.6	P121 E122 T123 H128 G129	P121-G125 PolarHBondContact O-N 3.47Å; E122-G125 PolarHBondContact O-N 2.88Å; T123-G125 VanDerWaalsContact C-N 3.33Å; T123-G125 PolarHBondContact O-N 2.87Å; G125-H128 PolarHBondContact O-N 3.46Å; G125-G129 PolarHBondContact O-N 3.41Å
126	M	87.9	Confident	87.6	Confident	72 Å²	72	52.5 Å²	52.5	36%	0.355	28%	0.276	S	S	.	.	H	α-helix	trans	-62.8	-43.2	175.6	-72.5	-169.9	-73	0	0	112.4	E122 T123 V124 H128 G129 S130	E122-M126 HydrophobicContact CG-CE 4.49Å; E122-M126 WeakPolarHBondContact O-CG 3.31Å; E122-M126 PolarHBondContact O-N 2.92Å; T123-M126 PolarHBondContact O-N 3.22Å; V124-M126 PolarHBondContact O-N 2.92Å; M126-H128 VanDerWaalsContact C-N 3.32Å; M126-H128 PolarHBondContact O-N 3.46Å; M126-G129 PolarHBondContact O-N 3.41Å; M126-S130 VanDerWaalsContact O-CB 3.29Å; M126-S130 WeakPolarHBondContact O-CB 3.31Å; M126-S130 PolarHBondContact O-N 2.88Å
127	I	90.4	Very high	88	Confident	0 Å²	0	54.6 Å²	54.6	0%	0	29%	0.29	C	S	.	.	H	α-helix	trans	-60.7	-45.3	176.5	-64.3	166.1	0	0	0	110	L91 I95 W119 T123 V124 S130 V180 I181	L91-I127 HydrophobicContact CD2-CG2 3.76Å; I95-I127 HydrophobicContact CD1-CG2 4.34Å; W119-I127 HydrophobicContact CD2-CD1 4.19Å; W119-I127 HydrophobicContact CE3-CD1 3.67Å; W119-I127 HydrophobicContact CH2-CD1 4.17Å; W119-I127 HydrophobicContact CZ3-CD1 3.66Å; T123-I127 HydrophobicContact CG2-CD1 4.17Å; T123-I127 VanDerWaalsContact O-CG1 3.32Å; T123-I127 WeakPolarHBondContact O-CG1 3.23Å; T123-I127 PolarHBondContact O-N 2.84Å; V124-I127 PolarHBondContact O-N 2.96Å; I127-S130 PolarHBondContact O-N 3.01Å; I127-S130 PolarHBondContact O-OG 3.07Å; I127-V180 HydrophobicContact CG2-CG1 3.78Å; I127-I181 HydrophobicContact CG1-CD1 4.28Å; I127-I181 HydrophobicContact CG1-CG1 3.76Å
128	H	83	Confident	88.3	Confident	77 Å²	77	53.8 Å²	53.8	36%	0.356	29%	0.287	S	S	.	.	H	α-helix	trans	-60	-46	175.8	-89	-65.2	0	0	0	113	G92 V124 G125 M126	G92-H128 WeakPolarHBondContact CA-CE1 3.47Å; V124-H128 PolarHBondContact O-CD2 3.5Å; V124-H128 PolarHBondContact O-N 3.38Å; G125-H128 PolarHBondContact O-N 3.46Å; M126-H128 VanDerWaalsContact C-N 3.32Å; M126-H128 PolarHBondContact O-N 3.46Å
129	G	85.3	Confident	88.6	Confident	23 Å²	23	46.2 Å²	46.2	24%	0.237	25%	0.247	C	C	.	.	H	α-helix	trans	-69.4	-32.4	-179.5	0	0	0	0	0	114	G125 M126 F131 F132	G125-G129 PolarHBondContact O-N 3.41Å; M126-G129 PolarHBondContact O-N 3.41Å; G129-F131 PolarHBondContact O-N 3.3Å; G129-F131 VanDerWaalsContact O-N 3.09Å; G129-F132 WeakPolarHBondContact O-CB 3.29Å; G129-F132 PolarHBondContact O-N 3.04Å
130	S	91.6	Very high	88.7	Confident	0 Å²	0	48.7 Å²	48.7	0%	0	26%	0.262	C	S	.	.	H	α-helix	trans	-58.2	-29.3	-172.1	67.1	0	0	0	0	114.9	M126 I127 F132 W133 R184 I185	M126-S130 VanDerWaalsContact O-CB 3.29Å; M126-S130 WeakPolarHBondContact O-CB 3.31Å; M126-S130 PolarHBondContact O-N 2.88Å; I127-S130 PolarHBondContact O-N 3.01Å; I127-S130 PolarHBondContact O-OG 3.07Å; S130-F132 VanDerWaalsContact C-N 3.31Å; S130-F132 PolarHBondContact O-N 3.31Å; S130-W133 PolarHBondContact O-N 3.43Å; S130-R184 VanDerWaalsContact OG-CB 3.26Å; S130-R184 WeakPolarHBondContact OG-CB 3.45Å; S130-I185 WeakPolarHBondContact O-CG1 3.39Å
131	F	91.3	Very high	89	Confident	3 Å²	3	48.3 Å²	48.3	1%	0.013	26%	0.263	C	S	.	.	H	α-helix	trans	-58.3	-42.9	172.5	174.8	-89.1	0	0	0	112	R88 G129 W133 G134 Y135 Q187 G188 E191	R88-F131 HydrophobicContact CG-CE1 4.42Å; G129-F131 PolarHBondContact O-N 3.3Å; G129-F131 VanDerWaalsContact O-N 3.09Å; F131-W133 VanDerWaalsContact C-N 3.29Å; F131-W133 PolarHBondContact O-N 2.89Å; F131-G134 PolarHBondContact O-N 3.07Å; F131-Y135 AromaticContact CE1-CD2 3.88Å; F131-Y135 HydrophobicContact CE1-CD2 3.88Å; F131-Y135 AromaticContact CE1-CG 3.97Å; F131-Y135 HydrophobicContact CE1-CG 3.97Å; F131-Y135 AromaticContact CZ-CD2 3.88Å; F131-Y135 HydrophobicContact CZ-CD2 3.88Å; F131-Y135 HydrophobicContact CZ-CE2 4.44Å; F131-Y135 HydrophobicContact CZ-CG 4.41Å; F131-Y135 WeakPolarHBondContact O-CB 3.42Å; F131-Y135 PolarHBondContact O-N 3.22Å; F131-Y135 VanDerWaalsContact O-N 3.12Å; F131-Q187 HydrophobicContact CD2-CB 4.27Å; F131-Q187 HydrophobicContact CE2-CB 4.36Å; F131-G188 WeakPolarHBondContact O-CA 3.49Å; F131-E191 HydrophobicContact CE2-CB 4.27Å; F131-E191 WeakPolarHBondContact CE2-OE2 3.47Å; F131-E191 HydrophobicContact CZ-CB 4.12Å; F131-E191 HydrophobicContact CZ-CG 4.3Å; F131-E191 WeakPolarHBondContact CZ-OE2 3.3Å
132	F	88.1	Confident	89.4	Confident	50 Å²	50	42.7 Å²	42.7	22%	0.219	23%	0.227	C	C	.	.	H	α-helix	trans	-69.1	-28.2	-175.7	-69.7	-75	0	0	0	112.6	G129 S130 Y135 I136 Y327	G129-F132 WeakPolarHBondContact O-CB 3.29Å; G129-F132 PolarHBondContact O-N 3.04Å; S130-F132 VanDerWaalsContact C-N 3.31Å; S130-F132 PolarHBondContact O-N 3.31Å; F132-Y135 PolarHBondContact O-N 2.92Å; F132-I136 VanDerWaalsContact O-CG1 3.31Å; F132-I136 WeakPolarHBondContact O-CG1 3.24Å; F132-I136 PolarHBondContact O-N 3.44Å; F132-Y327 AromaticContact CE1-CE1 3.79Å; F132-Y327 HydrophobicContact CE1-CE1 3.79Å; F132-Y327 AromaticContact CE1-CZ 3.98Å; F132-Y327 AromaticContact CZ-CE1 3.87Å; F132-Y327 HydrophobicContact CZ-CE1 3.87Å
133	W	90.3	Very high	89.6	Confident	114 Å²	114	35.7 Å²	35.7	43%	0.432	19%	0.194	S	C	.	.	H	α-helix	trans	-60.9	-48	176.7	-54.7	-21.6	0	0	0	111.7	S130 F131 I137 I181 I185	S130-W133 PolarHBondContact O-N 3.43Å; F131-W133 VanDerWaalsContact C-N 3.29Å; F131-W133 PolarHBondContact O-N 2.89Å; W133-I137 WeakPolarHBondContact O-CD1 3.46Å; W133-I137 WeakPolarHBondContact O-CG1 3.45Å; W133-I181 HydrophobicContact CZ3-CG2 4.36Å; W133-I185 HydrophobicContact CE3-CD1 3.98Å; W133-I185 HydrophobicContact CE3-CG1 4.17Å; W133-I185 HydrophobicContact CZ3-CD1 4.31Å
134	G	91.7	Very high	89.7	Confident	3 Å²	3	38.8 Å²	38.8	3%	0.031	21%	0.205	C	C	.	.	H	α-helix	trans	-68.8	-36.9	175.2	0	0	0	0	0	112.7	F131 T138 G188	F131-G134 PolarHBondContact O-N 3.07Å; G134-T138 PolarHBondContact O-N 3.29Å; G134-T138 PolarHBondContact O-OG1 3.49Å; G134-T138 VanDerWaalsContact O-OG1 3.08Å; G134-G188 VanDerWaalsContact C-C 3.48Å
135	Y	91.8	Very high	89.9	Confident	7 Å²	7	41.2 Å²	41.2	3%	0.027	22%	0.216	C	C	.	.	H	α-helix	trans	-63.1	-44.7	-177.5	-166.4	-108.6	0	0	0	112.7	F131 F132 T138 Q139 G188 E191 G192 Y195 T454	F131-Y135 AromaticContact CE1-CD2 3.88Å; F131-Y135 HydrophobicContact CE1-CD2 3.88Å; F131-Y135 AromaticContact CE1-CG 3.97Å; F131-Y135 HydrophobicContact CE1-CG 3.97Å; F131-Y135 AromaticContact CZ-CD2 3.88Å; F131-Y135 HydrophobicContact CZ-CD2 3.88Å; F131-Y135 HydrophobicContact CZ-CE2 4.44Å; F131-Y135 HydrophobicContact CZ-CG 4.41Å; F131-Y135 WeakPolarHBondContact O-CB 3.42Å; F131-Y135 PolarHBondContact O-N 3.22Å; F131-Y135 VanDerWaalsContact O-N 3.12Å; F132-Y135 PolarHBondContact O-N 2.92Å; Y135-T138 PolarHBondContact O-N 2.81Å; Y135-Q139 WeakPolarHBondContact O-CG 3.48Å; Y135-Q139 PolarHBondContact O-NE2 3.48Å; Y135-G188 VanDerWaalsContact CA-O 3.27Å; Y135-G188 WeakPolarHBondContact CA-O 3.42Å; Y135-G188 PolarHBondContact N-O 3.2Å; Y135-E191 HydrophobicContact CD2-CB 4.45Å; Y135-E191 HydrophobicContact CE2-CB 4.49Å; Y135-E191 HydrophobicContact CE2-CG 4.37Å; Y135-G192 VanDerWaalsContact CD2-CA 3.48Å; Y135-Y195 WeakPolarHBondContact OH-CD2 3.33Å; Y135-Y195 WeakPolarHBondContact OH-CE2 3.21Å; Y135-T454 HydrophobicContact CD1-CG2 3.73Å; Y135-T454 HydrophobicContact CE1-CG2 3.48Å; Y135-T454 VanDerWaalsContact CE1-CG2 3.48Å
136	I	90.9	Very high	90.1	Very high	42 Å²	42	39.4 Å²	39.4	22%	0.215	20%	0.197	C	C	.	.	H	α-helix	trans	-65.4	-47	-179.1	-68.3	165	0	0	0	111	F132 T138 Q139 M458	F132-I136 VanDerWaalsContact O-CG1 3.31Å; F132-I136 WeakPolarHBondContact O-CG1 3.24Å; F132-I136 PolarHBondContact O-N 3.44Å; I136-T138 PolarHBondContact O-N 3.28Å; I136-Q139 PolarHBondContact O-N 3.01Å; I136-M458 HydrophobicContact CD1-SD 4.39Å
137	I	91.8	Very high	89.9	Confident	124 Å²	124	36.9 Å²	36.9	64%	0.636	19%	0.187	S	C	*	.	H	α-helix	trans	-57.7	-35.6	-177.4	-68.6	170.8	0	0	0	111.1	W133 P141	W133-I137 WeakPolarHBondContact O-CD1 3.46Å; W133-I137 WeakPolarHBondContact O-CG1 3.45Å; I137-P141 WeakPolarHBondContact O-CD 3.49Å; I137-P141 WeakPolarHBondContact O-CG 3.43Å
138	T	93.2	Very high	89.6	Confident	14 Å²	14	44 Å²	44	9%	0.086	21%	0.214	C	C	.	.	H	α-helix	trans	-89.9	-7	-172.4	-46.5	0	0	0	0	113.9	G134 Y135 I136 G142 L189	G134-T138 PolarHBondContact O-N 3.29Å; G134-T138 PolarHBondContact O-OG1 3.49Å; G134-T138 VanDerWaalsContact O-OG1 3.08Å; Y135-T138 PolarHBondContact O-N 2.81Å; I136-T138 PolarHBondContact O-N 3.28Å; T138-G142 WeakPolarHBondContact O-CA 3.47Å; T138-G142 PolarHBondContact O-N 3.11Å; T138-L189 VanDerWaalsContact CB-O 3.29Å; T138-L189 WeakPolarHBondContact CB-O 3.29Å; T138-L189 HydrophobicContact CG2-CD2 4.39Å; T138-L189 WeakPolarHBondContact CG2-O 3.41Å; T138-L189 WeakPolarHBondContact OG1-CA 3.28Å; T138-L189 WeakPolarHBondContact OG1-CG 3.4Å; T138-L189 PolarHBondContact OG1-O 3.49Å
139	Q	92.3	Very high	89.7	Confident	0 Å²	0	45.3 Å²	45.3	0%	0	22%	0.223	C	C	.	.	H	α-helix	trans	-61.8	-50.4	-178.8	-67.3	-59.7	-32.9	0	0	112.8	Y135 I136 G143 G192 G447 N450	Y135-Q139 WeakPolarHBondContact O-CG 3.48Å; Y135-Q139 PolarHBondContact O-NE2 3.48Å; I136-Q139 PolarHBondContact O-N 3.01Å; Q139-G143 PolarHBondContact O-N 3.27Å; Q139-G192 PolarHBondContact NE2-O 2.95Å; Q139-G192 PolarHBondContact OE1-O 2.91Å; Q139-G447 WeakPolarHBondContact CB-O 3.39Å; Q139-G447 VanDerWaalsContact O-CA 3.27Å; Q139-G447 WeakPolarHBondContact O-CA 3.39Å; Q139-N450 VanDerWaalsContact CD-ND2 3.29Å; Q139-N450 PolarHBondContact NE2-ND2 3.01Å; Q139-N450 PolarHBondContact OE1-ND2 3.45Å
140	I	91.2	Very high	89.9	Confident	82 Å²	82	45.2 Å²	45.2	42%	0.421	22%	0.22	S	C	.	.	H	α-helix	trans	-72	-51.4	-178	-55.6	171.7	0	0	0	111	G142 G143 Y144 I448	I140-G142 VanDerWaalsContact C-N 3.29Å; I140-G142 PolarHBondContact O-N 3.26Å; I140-G143 PolarHBondContact O-N 2.97Å; I140-Y144 PolarHBondContact O-N 3.04Å; I140-I448 HydrophobicContact CG1-CG1 4.38Å; I140-I448 HydrophobicContact CG2-CG1 4.5Å
141	P	93.1	Very high	89.8	Confident	64 Å²	64	45.7 Å²	45.7	42%	0.416	22%	0.224	S	C	.	.	H	α-helix	trans	-60.7	-39.1	175.5	-22.2	34.5	0	0	0	112.2	I137 G143 Y144 I145	I137-P141 WeakPolarHBondContact O-CD 3.49Å; I137-P141 WeakPolarHBondContact O-CG 3.43Å; P141-G143 VanDerWaalsContact C-N 3.33Å; P141-G143 PolarHBondContact O-N 3.19Å; P141-Y144 WeakPolarHBondContact O-CB 3.23Å; P141-Y144 PolarHBondContact O-N 3.44Å; P141-Y144 VanDerWaalsContact O-N 3.11Å; P141-I145 VanDerWaalsContact O-CG1 3.28Å; P141-I145 WeakPolarHBondContact O-CG1 3.12Å; P141-I145 PolarHBondContact O-N 3.4Å
142	G	90.8	Very high	89.8	Confident	0 Å²	0	46.1 Å²	46.1	0%	0	23%	0.226	C	C	.	.	H	α-helix	trans	-60.6	-40.3	177.1	0	0	0	0	0	112.5	T138 I140 Y144 I145 A146 V193	T138-G142 WeakPolarHBondContact O-CA 3.47Å; T138-G142 PolarHBondContact O-N 3.11Å; I140-G142 VanDerWaalsContact C-N 3.29Å; I140-G142 PolarHBondContact O-N 3.26Å; G142-Y144 VanDerWaalsContact C-N 3.32Å; G142-Y144 PolarHBondContact O-N 3.08Å; G142-I145 PolarHBondContact O-N 3.2Å; G142-A146 WeakPolarHBondContact O-CB 3.26Å; G142-A146 PolarHBondContact O-N 3.09Å; G142-V193 WeakPolarHBondContact O-CG2 3.33Å
143	G	89.3	Confident	90.1	Very high	0 Å²	0	51.6 Å²	51.6	0%	0	25%	0.246	C	C	.	.	H	α-helix	trans	-63	-36.2	172.8	0	0	0	0	0	113.7	Q139 I140 P141 S147 S443	Q139-G143 PolarHBondContact O-N 3.27Å; I140-G143 PolarHBondContact O-N 2.97Å; P141-G143 VanDerWaalsContact C-N 3.33Å; P141-G143 PolarHBondContact O-N 3.19Å; G143-S147 WeakPolarHBondContact O-CB 3.38Å; G143-S147 PolarHBondContact O-N 3.35Å; G143-S147 VanDerWaalsContact O-N 3.15Å; G143-S443 WeakPolarHBondContact CA-O 3.3Å; G143-S443 WeakPolarHBondContact O-CB 3.41Å
144	Y	89.8	Confident	90.3	Very high	75 Å²	75	47.2 Å²	47.2	29%	0.294	23%	0.231	S	C	.	.	H	α-helix	trans	-72.6	-40.9	175.7	-166.5	-92.5	0	0	0	112.6	I140 P141 G142 S147 R148 W303 I444	I140-Y144 PolarHBondContact O-N 3.04Å; P141-Y144 WeakPolarHBondContact O-CB 3.23Å; P141-Y144 PolarHBondContact O-N 3.44Å; P141-Y144 VanDerWaalsContact O-N 3.11Å; G142-Y144 VanDerWaalsContact C-N 3.32Å; G142-Y144 PolarHBondContact O-N 3.08Å; Y144-S147 PolarHBondContact O-N 3.15Å; Y144-S147 PolarHBondContact O-OG 2.95Å; Y144-R148 HydrophobicContact CE1-CG 4.32Å; Y144-R148 VanDerWaalsContact CZ-NE 3.31Å; Y144-R148 PolarHBondContact O-N 2.7Å; Y144-R148 VanDerWaalsContact O-N 3.16Å; Y144-R148 PolarHBondContact OH-NE 3.41Å; Y144-R148 PolarHBondContact OH-NH2 3.09Å; Y144-W303 HydrophobicContact CD2-CZ2 4.14Å; Y144-W303 HydrophobicContact CE2-CZ2 4.25Å; Y144-I444 HydrophobicContact CD2-CD1 4.24Å
145	I	91.1	Very high	90.5	Very high	73 Å²	73	47 Å²	47	37%	0.374	23%	0.23	S	C	.	.	H	α-helix	trans	-61.5	-47.5	173.8	-70.7	168.8	0	0	0	109.6	P141 G142 S147 R148 L149 V154	P141-I145 VanDerWaalsContact O-CG1 3.28Å; P141-I145 WeakPolarHBondContact O-CG1 3.12Å; P141-I145 PolarHBondContact O-N 3.4Å; G142-I145 PolarHBondContact O-N 3.2Å; I145-S147 PolarHBondContact O-N 3.07Å; I145-R148 PolarHBondContact O-N 3.03Å; I145-L149 HydrophobicContact CB-CD1 4.37Å; I145-L149 HydrophobicContact CG2-CD1 3.55Å; I145-L149 WeakPolarHBondContact O-CB 3.36Å; I145-L149 PolarHBondContact O-N 3.22Å; I145-V154 HydrophobicContact CG2-CG1 4.25Å; I145-V154 HydrophobicContact CG2-CG2 4.13Å
146	A	88.3	Confident	90.7	Very high	4 Å²	4	46.7 Å²	46.7	3%	0.033	23%	0.228	C	C	.	.	H	α-helix	trans	-68.6	-15.5	179.5	0	0	0	0	0	114.2	G142 P196 A197	G142-A146 WeakPolarHBondContact O-CB 3.26Å; G142-A146 PolarHBondContact O-N 3.09Å; A146-P196 HydrophobicContact CB-CB 4.43Å; A146-A197 HydrophobicContact CB-CB 4.19Å
147	S	83.7	Confident	91	Very high	19 Å²	19	46.3 Å²	46.3	13%	0.133	23%	0.231	C	C	.	.	H	α-helix	trans	-86.4	-40	173.7	76.6	0	0	0	0	111.4	G143 Y144 I145 M296	G143-S147 WeakPolarHBondContact O-CB 3.38Å; G143-S147 PolarHBondContact O-N 3.35Å; G143-S147 VanDerWaalsContact O-N 3.15Å; Y144-S147 PolarHBondContact O-N 3.15Å; Y144-S147 PolarHBondContact O-OG 2.95Å; I145-S147 PolarHBondContact O-N 3.07Å; S147-M296 WeakPolarHBondContact O-CE 3.46Å
148	R	82.8	Confident	91.2	Very high	149 Å²	149	40.6 Å²	40.6	56%	0.562	20%	0.203	S	C	*	.	H	α-helix	trans	-84.3	-34	-178.9	-70.8	-166.7	170	-137.8	-5.8	114.6	Y144 I145	Y144-R148 HydrophobicContact CE1-CG 4.32Å; Y144-R148 VanDerWaalsContact CZ-NE 3.31Å; Y144-R148 PolarHBondContact O-N 2.7Å; Y144-R148 VanDerWaalsContact O-N 3.16Å; Y144-R148 PolarHBondContact OH-NE 3.41Å; Y144-R148 PolarHBondContact OH-NH2 3.09Å; I145-R148 PolarHBondContact O-N 3.03Å
149	L	86.3	Confident	91.3	Very high	106 Å²	106	40 Å²	40	56%	0.555	20%	0.199	S	C	*	.	S	Bend	trans	-99.9	164.8	-179.1	-68.9	141.1	0	0	0	110.7	I145 A151 V154	I145-L149 HydrophobicContact CB-CD1 4.37Å; I145-L149 HydrophobicContact CG2-CD1 3.55Å; I145-L149 WeakPolarHBondContact O-CB 3.36Å; I145-L149 PolarHBondContact O-N 3.22Å; L149-A151 PolarHBondContact O-N 3.08Å; L149-V154 HydrophobicContact CB-CG2 3.99Å
150	A	87.8	Confident	91.6	Very high	21 Å²	21	42.1 Å²	42.1	17%	0.174	21%	0.21	C	C	.	.			trans	-62.6	105.4	175.4	0	0	0	0	0	110.8	N152 R153 V154 E266	A150-N152 WeakPolarHBondContact CB-OD1 3.29Å; A150-N152 PolarHBondContact O-N 3.42Å; A150-N152 VanDerWaalsContact O-N 3.17Å; A150-R153 HydrophobicContact CB-CB 4.38Å; A150-R153 HydrophobicContact CB-CG 3.98Å; A150-R153 WeakPolarHBondContact O-CB 3.14Å; A150-R153 PolarHBondContact O-N 2.97Å; A150-V154 PolarHBondContact O-N 3.42Å; A150-V154 VanDerWaalsContact O-N 3.15Å; A150-E266 HydrophobicContact CB-CB 4.38Å; A150-E266 VanDerWaalsContact CB-CD 3.43Å; A150-E266 HydrophobicContact CB-CG 3.85Å; A150-E266 VanDerWaalsContact CB-OE1 3.26Å; A150-E266 WeakPolarHBondContact CB-OE1 3.23Å
151	A	90.3	Very high	91.9	Very high	10 Å²	10	42.2 Å²	42.2	8%	0.083	21%	0.211	C	C	.	.	H	α-helix	trans	-57.4	-32.7	-173.1	0	0	0	0	0	113.6	L149 V154 F155 I201	L149-A151 PolarHBondContact O-N 3.08Å; A151-V154 PolarHBondContact O-N 3.28Å; A151-F155 VanDerWaalsContact O-CB 3.31Å; A151-F155 WeakPolarHBondContact O-CB 3.2Å; A151-F155 PolarHBondContact O-N 3.43Å; A151-I201 HydrophobicContact CB-CG1 4.05Å
152	N	92.2	Very high	92.1	Very high	11 Å²	11	39.1 Å²	39.1	6%	0.059	19%	0.191	C	C	.	.	H	α-helix	trans	-63.2	-40.3	174.3	67.9	-41.3	0	0	0	112.8	A150 G156 I201 W260 S264 E266	A150-N152 WeakPolarHBondContact CB-OD1 3.29Å; A150-N152 PolarHBondContact O-N 3.42Å; A150-N152 VanDerWaalsContact O-N 3.17Å; N152-G156 PolarHBondContact O-N 3.18Å; N152-G156 VanDerWaalsContact O-N 3.07Å; N152-I201 HydrophobicContact CB-CG1 4.43Å; N152-W260 HydrophobicContact CB-CZ2 4.23Å; N152-W260 PolarHBondContact O-NE1 2.69Å; N152-S264 WeakPolarHBondContact CB-OG 3.21Å; N152-S264 PolarHBondContact ND2-O 3.41Å; N152-E266 PolarHBondContact ND2-N 3.17Å; N152-E266 WeakPolarHBondContact OD1-CG 3.14Å
153	R	93.4	Very high	92.3	Very high	166 Å²	166	39.1 Å²	39.1	63%	0.626	19%	0.191	S	C	*	.	H	α-helix	trans	-69.1	-43.1	177.3	-60.1	-171	-165.7	-166.7	1.9	110.6	A150 G156 A157 E266	A150-R153 HydrophobicContact CB-CB 4.38Å; A150-R153 HydrophobicContact CB-CG 3.98Å; A150-R153 WeakPolarHBondContact O-CB 3.14Å; A150-R153 PolarHBondContact O-N 2.97Å; R153-G156 PolarHBondContact O-N 2.92Å; R153-A157 VanDerWaalsContact O-CB 3.23Å; R153-A157 WeakPolarHBondContact O-CB 3.48Å; R153-A157 PolarHBondContact O-N 3.26Å; R153-E266 IonicContact CZ-OE1 3.09Å; R153-E266 IonicContact NE-OE1 3.82Å; R153-E266 PolarHBondContact NE-OE1 3.01Å; R153-E266 IonicContact NH2-OE1 2.72Å; R153-E266 PolarHBondContact NH2-OE1 3.47Å
154	V	95	Very high	92.7	Very high	21 Å²	21	41.5 Å²	41.5	13%	0.127	21%	0.206	C	C	.	.	H	α-helix	trans	-61.2	-47	177.7	178.9	0	0	0	0	110.7	I145 L149 A150 A151 A157 A158 V193 A197	I145-V154 HydrophobicContact CG2-CG1 4.25Å; I145-V154 HydrophobicContact CG2-CG2 4.13Å; L149-V154 HydrophobicContact CB-CG2 3.99Å; A150-V154 PolarHBondContact O-N 3.42Å; A150-V154 VanDerWaalsContact O-N 3.15Å; A151-V154 PolarHBondContact O-N 3.28Å; V154-A157 PolarHBondContact O-N 3.05Å; V154-A158 WeakPolarHBondContact O-CB 3.39Å; V154-A158 PolarHBondContact O-N 2.92Å; V154-V193 HydrophobicContact CG1-CB 4.28Å; V154-V193 HydrophobicContact CG1-CG1 3.86Å; V154-V193 HydrophobicContact CG1-CG2 3.37Å; V154-A197 HydrophobicContact CB-CB 4.5Å; V154-A197 HydrophobicContact CG1-CB 4.3Å
155	F	96.4	Very high	93	Very high	0 Å²	0	39.1 Å²	39.1	0%	0	20%	0.198	C	C	.	.	H	α-helix	trans	-59.9	-48.2	177.3	-174.9	-97.8	0	0	0	112.4	F81 A151 A158 I159 T194 A197 C198 I201 W256 W260	F81-F155 HydrophobicContact CD2-CE2 4.35Å; F81-F155 HydrophobicContact CD2-CZ 4.21Å; F81-F155 HydrophobicContact CE1-CE2 4.48Å; F81-F155 AromaticContact CE2-CE2 3.85Å; F81-F155 HydrophobicContact CE2-CE2 3.85Å; F81-F155 HydrophobicContact CE2-CZ 4.12Å; F81-F155 AromaticContact CZ-CE2 3.91Å; F81-F155 HydrophobicContact CZ-CE2 3.91Å; A151-F155 VanDerWaalsContact O-CB 3.31Å; A151-F155 WeakPolarHBondContact O-CB 3.2Å; A151-F155 PolarHBondContact O-N 3.43Å; F155-A158 PolarHBondContact O-N 3.47Å; F155-I159 HydrophobicContact CD1-CD1 3.95Å; F155-I159 HydrophobicContact CE1-CD1 3.46Å; F155-I159 VanDerWaalsContact CE1-CD1 3.46Å; F155-I159 HydrophobicContact CE2-CD1 4.39Å; F155-I159 HydrophobicContact CZ-CD1 3.72Å; F155-I159 PolarHBondContact O-N 3.03Å; F155-T194 HydrophobicContact CD2-CG2 3.75Å; F155-T194 WeakPolarHBondContact CD2-O 3.47Å; F155-T194 HydrophobicContact CE2-CG2 3.35Å; F155-T194 HydrophobicContact CZ-CG2 4.19Å; F155-A197 HydrophobicContact CB-CB 3.94Å; F155-A197 HydrophobicContact CD2-CB 4.29Å; F155-C198 HydrophobicContact CD2-CB 4.48Å; F155-C198 HydrophobicContact CE2-CB 4.28Å; F155-I201 HydrophobicContact CB-CD1 4.07Å; F155-I201 HydrophobicContact CD1-CD1 4.49Å; F155-I201 HydrophobicContact CG-CD1 4.2Å; F155-W256 AromaticContact CD1-CH2 3.95Å; F155-W256 HydrophobicContact CD1-CH2 3.95Å; F155-W256 HydrophobicContact CD1-CZ2 4.48Å; F155-W256 AromaticContact CE1-CH2 3.74Å; F155-W256 HydrophobicContact CE1-CH2 3.74Å; F155-W256 AromaticContact CE1-CZ2 3.89Å; F155-W256 HydrophobicContact CE1-CZ2 3.89Å; F155-W260 HydrophobicContact CB-CZ2 4.35Å; F155-W260 AromaticContact CD1-CE2 3.97Å; F155-W260 AromaticContact CD1-CH2 3.74Å; F155-W260 HydrophobicContact CD1-CH2 3.74Å; F155-W260 AromaticContact CD1-CZ2 3.52Å; F155-W260 HydrophobicContact CD1-CZ2 3.52Å; F155-W260 HydrophobicContact CD1-CZ3 4.35Å; F155-W260 HydrophobicContact CE1-CH2 4.04Å; F155-W260 HydrophobicContact CE1-CZ2 4.26Å; F155-W260 HydrophobicContact CE1-CZ3 4.31Å; F155-W260 HydrophobicContact CG-CZ2 4.32Å
156	G	96.1	Very high	93.3	Very high	0 Å²	0	35.7 Å²	35.7	0%	0	18%	0.18	C	C	.	.	H	α-helix	trans	-63.3	-44.7	177.9	0	0	0	0	0	112.7	N152 R153 A158 I159 L160 Y257	N152-G156 PolarHBondContact O-N 3.18Å; N152-G156 VanDerWaalsContact O-N 3.07Å; R153-G156 PolarHBondContact O-N 2.92Å; G156-A158 VanDerWaalsContact C-N 3.33Å; G156-A158 PolarHBondContact O-N 2.9Å; G156-I159 PolarHBondContact O-N 3.18Å; G156-L160 PolarHBondContact O-N 3.49Å; G156-Y257 WeakPolarHBondContact O-CD2 3.48Å; G156-Y257 WeakPolarHBondContact O-CE2 3.4Å
157	A	95.8	Very high	93.6	Very high	34 Å²	34	37.9 Å²	37.9	28%	0.281	19%	0.19	S	C	.	.	H	α-helix	trans	-62.5	-39.6	178.7	0	0	0	0	0	112	R153 V154 I159 L160 L161	R153-A157 VanDerWaalsContact O-CB 3.23Å; R153-A157 WeakPolarHBondContact O-CB 3.48Å; R153-A157 PolarHBondContact O-N 3.26Å; V154-A157 PolarHBondContact O-N 3.05Å; A157-I159 PolarHBondContact O-N 3.15Å; A157-L160 PolarHBondContact O-N 2.95Å; A157-L161 VanDerWaalsContact O-CB 3.31Å; A157-L161 WeakPolarHBondContact O-CB 3.39Å; A157-L161 VanDerWaalsContact O-CG 3.22Å; A157-L161 WeakPolarHBondContact O-CG 3.19Å; A157-L161 PolarHBondContact O-N 3.01Å
158	A	96.4	Very high	94.2	Very high	4 Å²	4	41.3 Å²	41.3	3%	0.033	21%	0.206	C	C	.	.	H	α-helix	trans	-58	-46.7	176	0	0	0	0	0	111.9	V154 F155 G156 L161 T162 V190 V193	V154-A158 WeakPolarHBondContact O-CB 3.39Å; V154-A158 PolarHBondContact O-N 2.92Å; F155-A158 PolarHBondContact O-N 3.47Å; G156-A158 VanDerWaalsContact C-N 3.33Å; G156-A158 PolarHBondContact O-N 2.9Å; A158-L161 PolarHBondContact O-N 3.2Å; A158-T162 WeakPolarHBondContact O-CG2 3.27Å; A158-T162 PolarHBondContact O-N 2.93Å; A158-V190 WeakPolarHBondContact CB-O 3.5Å; A158-V193 HydrophobicContact CB-CG1 3.67Å
159	I	96.4	Very high	94.8	Very high	0 Å²	0	34.2 Å²	34.2	0%	0	18%	0.18	C	C	.	.	H	α-helix	trans	-68	-42.4	179.7	-66	163.9	0	0	0	111.1	F155 G156 A157 L161 T162 S163 W256	F155-I159 HydrophobicContact CD1-CD1 3.95Å; F155-I159 HydrophobicContact CE1-CD1 3.46Å; F155-I159 VanDerWaalsContact CE1-CD1 3.46Å; F155-I159 HydrophobicContact CE2-CD1 4.39Å; F155-I159 HydrophobicContact CZ-CD1 3.72Å; F155-I159 PolarHBondContact O-N 3.03Å; G156-I159 PolarHBondContact O-N 3.18Å; A157-I159 PolarHBondContact O-N 3.15Å; I159-L161 PolarHBondContact O-N 3.49Å; I159-T162 VanDerWaalsContact O-CG2 3.3Å; I159-T162 WeakPolarHBondContact O-CG2 3.44Å; I159-S163 VanDerWaalsContact O-CB 3.29Å; I159-S163 WeakPolarHBondContact O-CB 3.47Å; I159-S163 PolarHBondContact O-N 2.89Å; I159-S163 PolarHBondContact O-OG 3.08Å; I159-W256 HydrophobicContact CB-CE3 4.07Å; I159-W256 HydrophobicContact CB-CH2 4.32Å; I159-W256 HydrophobicContact CB-CZ3 3.61Å; I159-W256 HydrophobicContact CD1-CE3 4.21Å; I159-W256 HydrophobicContact CD1-CH2 3.24Å; I159-W256 HydrophobicContact CD1-CZ2 3.83Å; I159-W256 HydrophobicContact CD1-CZ3 3.45Å; I159-W256 VanDerWaalsContact CD1-CZ3 3.45Å; I159-W256 HydrophobicContact CG1-CH2 4.34Å; I159-W256 HydrophobicContact CG1-CZ3 4.12Å; I159-W256 HydrophobicContact CG2-CD2 4.37Å; I159-W256 HydrophobicContact CG2-CE3 3.53Å; I159-W256 HydrophobicContact CG2-CZ3 3.63Å
160	L	97.6	Very high	95.2	Very high	46 Å²	46	29.1 Å²	29.1	24%	0.241	15%	0.153	C	C	.	.	H	α-helix	trans	-61	-47	175.5	-179.8	68.7	0	0	0	111.9	G156 A157 S163 T164 M254 Y257	G156-L160 PolarHBondContact O-N 3.49Å; A157-L160 PolarHBondContact O-N 2.95Å; L160-S163 PolarHBondContact O-N 3.01Å; L160-T164 HydrophobicContact CD1-CG2 4.38Å; L160-T164 WeakPolarHBondContact O-CG2 3.41Å; L160-T164 PolarHBondContact O-N 3.33Å; L160-T164 PolarHBondContact O-OG1 3.46Å; L160-M254 HydrophobicContact CD1-CG 4.04Å; L160-Y257 HydrophobicContact CB-CD1 4.32Å; L160-Y257 HydrophobicContact CB-CD2 3.94Å; L160-Y257 HydrophobicContact CB-CE2 4.3Å; L160-Y257 HydrophobicContact CB-CG 3.93Å; L160-Y257 HydrophobicContact CD1-CD1 3.99Å; L160-Y257 HydrophobicContact CD1-CG 4.12Å; L160-Y257 HydrophobicContact CD2-CD1 3.79Å; L160-Y257 HydrophobicContact CD2-CE1 3.63Å; L160-Y257 HydrophobicContact CD2-CE2 4.49Å; L160-Y257 HydrophobicContact CD2-CG 4.26Å; L160-Y257 HydrophobicContact CG-CD1 4.24Å; L160-Y257 HydrophobicContact CG-CG 4.32Å
161	L	97	Very high	95.5	Very high	83 Å²	83	31 Å²	31	44%	0.435	17%	0.165	S	C	.	.	H	α-helix	trans	-66.1	-43.8	-178.9	-71.1	172.3	0	0	0	111.6	A157 A158 I159 S163 T164 L165 V190	A157-L161 VanDerWaalsContact O-CB 3.31Å; A157-L161 WeakPolarHBondContact O-CB 3.39Å; A157-L161 VanDerWaalsContact O-CG 3.22Å; A157-L161 WeakPolarHBondContact O-CG 3.19Å; A157-L161 PolarHBondContact O-N 3.01Å; A158-L161 PolarHBondContact O-N 3.2Å; I159-L161 PolarHBondContact O-N 3.49Å; L161-S163 VanDerWaalsContact C-N 3.31Å; L161-S163 PolarHBondContact O-N 3.38Å; L161-T164 WeakPolarHBondContact CA-OG1 3.36Å; L161-T164 PolarHBondContact O-N 3.39Å; L161-T164 PolarHBondContact O-OG1 2.97Å; L161-L165 WeakPolarHBondContact O-CB 3.22Å; L161-L165 VanDerWaalsContact O-CG 3.23Å; L161-L165 WeakPolarHBondContact O-CG 3.48Å; L161-L165 PolarHBondContact O-N 3.23Å; L161-V190 HydrophobicContact CB-CB 4.2Å; L161-V190 HydrophobicContact CB-CG1 4.14Å; L161-V190 HydrophobicContact CB-CG2 4.2Å; L161-V190 HydrophobicContact CD1-CG1 4.22Å
162	T	96.9	Very high	95.7	Very high	0 Å²	0	31.1 Å²	31.1	0%	0	17%	0.166	C	C	.	.	H	α-helix	trans	-64.5	-37.4	176.7	-167.9	0	0	0	0	111.8	I87 A158 I159 N166 Q187	I87-T162 HydrophobicContact CD1-CG2 4.14Å; A158-T162 WeakPolarHBondContact O-CG2 3.27Å; A158-T162 PolarHBondContact O-N 2.93Å; I159-T162 VanDerWaalsContact O-CG2 3.3Å; I159-T162 WeakPolarHBondContact O-CG2 3.44Å; T162-N166 VanDerWaalsContact O-CB 3.28Å; T162-N166 WeakPolarHBondContact O-CB 3.22Å; T162-N166 PolarHBondContact O-N 3.17Å; T162-Q187 PolarHBondContact O-NE2 3.33Å
163	S	96.9	Very high	95.7	Very high	0 Å²	0	30.7 Å²	30.7	0%	0	16%	0.164	C	C	.	.	H	α-helix	trans	-68.3	-41.1	177.3	-68.5	0	0	0	0	113.3	I87 I159 L160 L161 N166 M167 G250 G253	I87-S163 WeakPolarHBondContact CD1-OG 3.38Å; I159-S163 VanDerWaalsContact O-CB 3.29Å; I159-S163 WeakPolarHBondContact O-CB 3.47Å; I159-S163 PolarHBondContact O-N 2.89Å; I159-S163 PolarHBondContact O-OG 3.08Å; L160-S163 PolarHBondContact O-N 3.01Å; L161-S163 VanDerWaalsContact C-N 3.31Å; L161-S163 PolarHBondContact O-N 3.38Å; S163-N166 WeakPolarHBondContact O-CB 3.4Å; S163-N166 PolarHBondContact O-N 3.42Å; S163-M167 WeakPolarHBondContact O-CG 3.27Å; S163-M167 PolarHBondContact O-N 2.96Å; S163-G250 WeakPolarHBondContact O-CA 3.43Å; S163-G253 WeakPolarHBondContact OG-CA 3.25Å
164	T	96.9	Very high	95.6	Very high	50 Å²	50	29.6 Å²	29.6	31%	0.307	16%	0.16	S	C	.	.	H	α-helix	trans	-67.2	-43.8	175.2	50.4	0	0	0	0	111.5	L160 L161 N166 M167 M254	L160-T164 HydrophobicContact CD1-CG2 4.38Å; L160-T164 WeakPolarHBondContact O-CG2 3.41Å; L160-T164 PolarHBondContact O-N 3.33Å; L160-T164 PolarHBondContact O-OG1 3.46Å; L161-T164 WeakPolarHBondContact CA-OG1 3.36Å; L161-T164 PolarHBondContact O-N 3.39Å; L161-T164 PolarHBondContact O-OG1 2.97Å; T164-N166 VanDerWaalsContact C-N 3.27Å; T164-N166 PolarHBondContact O-N 2.69Å; T164-M167 WeakPolarHBondContact O-CB 3.5Å; T164-M167 PolarHBondContact O-N 2.9Å; T164-M254 HydrophobicContact CG2-SD 4.44Å
165	L	96.9	Very high	95.6	Very high	25 Å²	25	34 Å²	34	13%	0.131	19%	0.186	C	C	.	.	H	α-helix	trans	-60.3	-37.6	172.7	-70.9	172.9	0	0	0	111.9	L161 M167 L168 V183 L186 Q187 V190	L161-L165 WeakPolarHBondContact O-CB 3.22Å; L161-L165 VanDerWaalsContact O-CG 3.23Å; L161-L165 WeakPolarHBondContact O-CG 3.48Å; L161-L165 PolarHBondContact O-N 3.23Å; L165-M167 VanDerWaalsContact C-N 3.27Å; L165-M167 PolarHBondContact O-N 3.16Å; L165-L168 HydrophobicContact CD2-CD1 4.19Å; L165-L168 WeakPolarHBondContact O-CB 3.22Å; L165-L168 PolarHBondContact O-N 3.27Å; L165-V183 HydrophobicContact CB-CG1 4.2Å; L165-V183 WeakPolarHBondContact O-CG1 3.29Å; L165-L186 HydrophobicContact CD1-CB 3.79Å; L165-L186 HydrophobicContact CD2-CB 4.38Å; L165-L186 HydrophobicContact CD2-CD1 4.31Å; L165-Q187 HydrophobicContact CB-CG 3.62Å; L165-Q187 HydrophobicContact CD1-CG 4.08Å; L165-V190 HydrophobicContact CD1-CG1 4.49Å; L165-V190 HydrophobicContact CD1-CG2 4.08Å
166	N	95.7	Very high	95.4	Very high	0 Å²	0	38.4 Å²	38.4	0%	0	21%	0.207	C	C	.	.	H	α-helix	trans	-60.5	-37.8	177.1	-169	64.6	0	0	0	111.9	I87 N90 T162 S163 T164 L168 I169 Q187 F246	I87-N166 HydrophobicContact CD1-CB 4.38Å; I87-N166 HydrophobicContact CG2-CB 4.11Å; I87-N166 WeakPolarHBondContact CG2-OD1 3.46Å; N90-N166 PolarHBondContact ND2-ND2 3.09Å; N90-N166 PolarHBondContact ND2-OD1 2.81Å; T162-N166 VanDerWaalsContact O-CB 3.28Å; T162-N166 WeakPolarHBondContact O-CB 3.22Å; T162-N166 PolarHBondContact O-N 3.17Å; S163-N166 WeakPolarHBondContact O-CB 3.4Å; S163-N166 PolarHBondContact O-N 3.42Å; T164-N166 VanDerWaalsContact C-N 3.27Å; T164-N166 PolarHBondContact O-N 2.69Å; N166-L168 PolarHBondContact O-N 3.41Å; N166-I169 WeakPolarHBondContact O-CB 3.47Å; N166-I169 WeakPolarHBondContact O-CG1 3.45Å; N166-I169 PolarHBondContact O-N 3.29Å; N166-Q187 VanDerWaalsContact CB-NE2 3.3Å; N166-F246 WeakPolarHBondContact ND2-CA 3.36Å; N166-F246 PolarHBondContact ND2-O 3.19Å; N166-F246 WeakPolarHBondContact O-CB 3.09Å; N166-F246 WeakPolarHBondContact OD1-CD1 3.4Å
167	M	96.2	Very high	95.2	Very high	50 Å²	50	42.5 Å²	42.5	25%	0.246	22%	0.223	C	C	.	.	H	α-helix	trans	-67	-19.3	176.9	-64.6	175	67	0	0	113.4	S163 T164 L165 P170 Y247 M254	S163-M167 WeakPolarHBondContact O-CG 3.27Å; S163-M167 PolarHBondContact O-N 2.96Å; T164-M167 WeakPolarHBondContact O-CB 3.5Å; T164-M167 PolarHBondContact O-N 2.9Å; L165-M167 VanDerWaalsContact C-N 3.27Å; L165-M167 PolarHBondContact O-N 3.16Å; M167-P170 WeakPolarHBondContact O-CD 3.47Å; M167-Y247 HydrophobicContact CB-CD1 4.26Å; M167-Y247 HydrophobicContact CE-CD1 4.32Å; M167-Y247 HydrophobicContact CG-CD1 4.41Å; M167-Y247 WeakPolarHBondContact O-CE1 3.33Å; M167-M254 HydrophobicContact CE-CE 3.95Å; M167-M254 HydrophobicContact SD-CE 3.54Å; M167-M254 VanDerWaalsContact SD-CE 3.54Å; M167-M254 HydrophobicContact SD-SD 4.15Å
168	L	95.9	Very high	95.1	Very high	91 Å²	91	42.2 Å²	42.2	48%	0.476	22%	0.224	S	C	.	.	H	α-helix	trans	-81.9	-17.5	177.3	-60.3	174.9	0	0	0	113	L165 N166 S171 A172	L165-L168 HydrophobicContact CD2-CD1 4.19Å; L165-L168 WeakPolarHBondContact O-CB 3.22Å; L165-L168 PolarHBondContact O-N 3.27Å; N166-L168 PolarHBondContact O-N 3.41Å; L168-S171 WeakPolarHBondContact O-CB 3.38Å; L168-S171 PolarHBondContact O-N 3.17Å; L168-S171 VanDerWaalsContact O-N 3.1Å; L168-A172 PolarHBondContact O-N 3.36Å
169	I	95.1	Very high	95.1	Very high	0 Å²	0	44.3 Å²	44.3	0%	0	24%	0.237	C	C	.	.	H	α-helix	trans	-55.4	-45.6	-176.8	-65.8	-72	0	0	0	112.8	N166 S171 A172 A173 V180 V183 R184 F246	N166-I169 WeakPolarHBondContact O-CB 3.47Å; N166-I169 WeakPolarHBondContact O-CG1 3.45Å; N166-I169 PolarHBondContact O-N 3.29Å; I169-S171 VanDerWaalsContact C-N 3.28Å; I169-S171 PolarHBondContact O-N 3.07Å; I169-A172 PolarHBondContact O-N 2.95Å; I169-A173 WeakPolarHBondContact O-CB 3.47Å; I169-A173 PolarHBondContact O-N 3.27Å; I169-V180 HydrophobicContact CD1-CG1 4.13Å; I169-V180 HydrophobicContact CG2-CG1 4.46Å; I169-V183 HydrophobicContact CD1-CB 3.88Å; I169-V183 HydrophobicContact CD1-CG1 3.51Å; I169-V183 HydrophobicContact CG1-CG1 4.1Å; I169-R184 HydrophobicContact CD1-CG 4.29Å; I169-F246 HydrophobicContact CB-CD1 3.73Å; I169-F246 HydrophobicContact CB-CE1 3.95Å; I169-F246 HydrophobicContact CB-CG 4.19Å; I169-F246 HydrophobicContact CG1-CD1 4.17Å; I169-F246 HydrophobicContact CG1-CE1 4.32Å; I169-F246 HydrophobicContact CG2-CD1 3.77Å; I169-F246 HydrophobicContact CG2-CD2 4.46Å; I169-F246 HydrophobicContact CG2-CE1 3.48Å; I169-F246 VanDerWaalsContact CG2-CE1 3.48Å; I169-F246 HydrophobicContact CG2-CE2 4.2Å; I169-F246 HydrophobicContact CG2-CG 4.26Å; I169-F246 HydrophobicContact CG2-CZ 3.7Å
170	P	94.3	Very high	95	Very high	0 Å²	0	44.3 Å²	44.3	0%	0	24%	0.237	C	C	.	.	H	α-helix	trans	-61.3	-35.9	178	-24.2	35.1	0	0	0	113.7	M167 R174 W242 F246 Y247	M167-P170 WeakPolarHBondContact O-CD 3.47Å; P170-R174 WeakPolarHBondContact O-CG 3.39Å; P170-R174 PolarHBondContact O-NH1 3.17Å; P170-W242 HydrophobicContact CB-CH2 3.92Å; P170-W242 HydrophobicContact CB-CZ3 3.86Å; P170-W242 HydrophobicContact CG-CZ3 4.29Å; P170-F246 HydrophobicContact CG-CB 3.68Å; P170-F246 HydrophobicContact CG-CD2 3.82Å; P170-F246 HydrophobicContact CG-CG 3.94Å; P170-Y247 HydrophobicContact CB-CE2 4.43Å; P170-Y247 HydrophobicContact CG-CE1 4.33Å; P170-Y247 HydrophobicContact CG-CE2 4.18Å
171	S	94.2	Very high	94.9	Very high	60 Å²	60	43.4 Å²	43.4	42%	0.42	23%	0.233	S	C	.	.	H	α-helix	trans	-70.1	-44.5	177.3	-49.3	0	0	0	0	110.4	L168 I169 A173 R174	L168-S171 WeakPolarHBondContact O-CB 3.38Å; L168-S171 PolarHBondContact O-N 3.17Å; L168-S171 VanDerWaalsContact O-N 3.1Å; I169-S171 VanDerWaalsContact C-N 3.28Å; I169-S171 PolarHBondContact O-N 3.07Å; S171-A173 PolarHBondContact O-N 2.86Å; S171-R174 PolarHBondContact O-N 3.1Å
172	A	93.9	Very high	94.9	Very high	12 Å²	12	45.7 Å²	45.7	10%	0.099	24%	0.239	C	C	.	.	H	α-helix	trans	-61.6	-43.2	177.7	0	0	0	0	0	112.5	L168 I169 R174 V175 H176 C179 V180 V183	L168-A172 PolarHBondContact O-N 3.36Å; I169-A172 PolarHBondContact O-N 2.95Å; A172-R174 VanDerWaalsContact C-N 3.26Å; A172-R174 PolarHBondContact O-N 3.04Å; A172-V175 PolarHBondContact O-N 3.38Å; A172-V175 VanDerWaalsContact O-N 3.1Å; A172-H176 PolarHBondContact O-N 3.42Å; A172-C179 HydrophobicContact CB-CB 3.81Å; A172-V180 HydrophobicContact CB-CG2 4.17Å; A172-V183 HydrophobicContact CB-CG2 4.23Å
173	A	92.5	Very high	94.9	Very high	3 Å²	3	46.3 Å²	46.3	3%	0.025	24%	0.243	C	C	.	.	H	α-helix	trans	-60.8	-34.7	179.8	0	0	0	0	0	112.8	M98 F117 W119 I169 S171 V175 V180 W242	M98-A173 HydrophobicContact CE-CB 3.68Å; F117-A173 HydrophobicContact CE1-CB 4.43Å; F117-A173 WeakPolarHBondContact CE1-O 3.47Å; F117-A173 HydrophobicContact CE2-CB 4.39Å; F117-A173 HydrophobicContact CZ-CB 3.96Å; W119-A173 HydrophobicContact CH2-CB 4.11Å; W119-A173 HydrophobicContact CZ2-CB 4.4Å; I169-A173 WeakPolarHBondContact O-CB 3.47Å; I169-A173 PolarHBondContact O-N 3.27Å; S171-A173 PolarHBondContact O-N 2.86Å; A173-V175 VanDerWaalsContact C-N 3.29Å; A173-V175 PolarHBondContact O-N 2.92Å; A173-V180 VanDerWaalsContact CA-CG2 3.45Å; A173-V180 HydrophobicContact CB-CG2 3.85Å; A173-W242 HydrophobicContact CB-CH2 4.05Å; A173-W242 HydrophobicContact CB-CZ3 4.25Å
174	R	92.2	Very high	94.8	Very high	142 Å²	142	46.6 Å²	46.6	54%	0.536	24%	0.244	S	C	.	.	H	α-helix	trans	-70.5	-21.9	177.8	-70.3	179	-175.2	97	-7.4	113.9	F117 P170 S171 A172	F117-R174 HydrophobicContact CZ-CG 4.5Å; P170-R174 WeakPolarHBondContact O-CG 3.39Å; P170-R174 PolarHBondContact O-NH1 3.17Å; S171-R174 PolarHBondContact O-N 3.1Å; A172-R174 VanDerWaalsContact C-N 3.26Å; A172-R174 PolarHBondContact O-N 3.04Å
175	V	93.6	Very high	94.8	Very high	113 Å²	113	46.8 Å²	46.8	69%	0.685	24%	0.243	S	C	*	.	H	α-helix	trans	-88	-61.8	179.1	179.1	0	0	0	0	110.1	A172 A173	A172-V175 PolarHBondContact O-N 3.38Å; A172-V175 VanDerWaalsContact O-N 3.1Å; A173-V175 VanDerWaalsContact C-N 3.29Å; A173-V175 PolarHBondContact O-N 2.92Å
176	H	92.9	Very high	94.8	Very high	94 Å²	94	48.2 Å²	48.2	44%	0.435	25%	0.25	S	S	.	.			trans	-166.9	150.5	-177	-165.7	-106.2	0	0	0	111	A172 G178 C179	A172-H176 PolarHBondContact O-N 3.42Å; H176-G178 PolarHBondContact ND1-N 3.01Å; H176-G178 PolarHBondContact O-N 3.33Å; H176-C179 WeakPolarHBondContact O-CB 3.5Å; H176-C179 PolarHBondContact O-N 3.06Å
177	Y	92	Very high	94.8	Very high	85 Å²	85	48.2 Å²	48.2	33%	0.333	25%	0.25	S	S	.	.	H	α-helix	trans	-59.9	-32.5	176.6	64.3	-94.6	0	0	0	112.5	T123 C179 V180 I181	T123-Y177 HydrophobicContact CG2-CD1 4.33Å; T123-Y177 HydrophobicContact CG2-CD2 3.64Å; T123-Y177 HydrophobicContact CG2-CE2 4.19Å; T123-Y177 HydrophobicContact CG2-CG 3.73Å; Y177-C179 VanDerWaalsContact C-N 3.26Å; Y177-C179 PolarHBondContact O-N 3.18Å; Y177-V180 WeakPolarHBondContact O-CA 3.44Å; Y177-V180 WeakPolarHBondContact O-CB 3.4Å; Y177-V180 PolarHBondContact O-N 3.35Å; Y177-I181 HydrophobicContact CD2-CD1 4.01Å; Y177-I181 PolarHBondContact O-N 3.24Å
178	G	94.1	Very high	94.7	Very high	29 Å²	29	45.9 Å²	45.9	30%	0.299	24%	0.239	S	C	.	.	H	α-helix	trans	-60.3	-32.5	175.4	0	0	0	0	0	113.7	H176 V180 I181 F182	H176-G178 PolarHBondContact ND1-N 3.01Å; H176-G178 PolarHBondContact O-N 3.33Å; G178-V180 VanDerWaalsContact C-N 3.34Å; G178-I181 PolarHBondContact O-N 3.38Å; G178-F182 PolarHBondContact O-N 2.92Å
179	C	95.4	Very high	94.7	Very high	47 Å²	47	45.2 Å²	45.2	32%	0.318	24%	0.235	S	C	.	.	H	α-helix	trans	-68.4	-36.5	173.7	-60.8	0	0	0	0	111.2	A172 H176 Y177 F182 V183	A172-C179 HydrophobicContact CB-CB 3.81Å; H176-C179 WeakPolarHBondContact O-CB 3.5Å; H176-C179 PolarHBondContact O-N 3.06Å; Y177-C179 VanDerWaalsContact C-N 3.26Å; Y177-C179 PolarHBondContact O-N 3.18Å; C179-F182 PolarHBondContact O-N 3.25Å; C179-V183 WeakPolarHBondContact O-CG2 3.45Å; C179-V183 PolarHBondContact O-N 3.16Å
180	V	94.9	Very high	94.7	Very high	0 Å²	0	46.5 Å²	46.5	0%	0	24%	0.243	C	C	.	.	H	α-helix	trans	-65.1	-44.1	175.6	-174.9	0	0	0	0	110.4	W119 I127 I169 A172 A173 Y177 G178 F182 V183 R184	W119-V180 HydrophobicContact CH2-CG2 4.08Å; W119-V180 HydrophobicContact CZ2-CG2 4.42Å; I127-V180 HydrophobicContact CG2-CG1 3.78Å; I169-V180 HydrophobicContact CD1-CG1 4.13Å; I169-V180 HydrophobicContact CG2-CG1 4.46Å; A172-V180 HydrophobicContact CB-CG2 4.17Å; A173-V180 VanDerWaalsContact CA-CG2 3.45Å; A173-V180 HydrophobicContact CB-CG2 3.85Å; Y177-V180 WeakPolarHBondContact O-CA 3.44Å; Y177-V180 WeakPolarHBondContact O-CB 3.4Å; Y177-V180 PolarHBondContact O-N 3.35Å; G178-V180 VanDerWaalsContact C-N 3.34Å; V180-F182 VanDerWaalsContact C-N 3.34Å; V180-F182 PolarHBondContact O-N 3.17Å; V180-V183 PolarHBondContact O-N 2.96Å; V180-R184 VanDerWaalsContact O-CB 3.3Å; V180-R184 WeakPolarHBondContact O-CB 3.38Å; V180-R184 WeakPolarHBondContact O-CG 3.31Å; V180-R184 PolarHBondContact O-N 3.02Å
181	I	95.3	Very high	94.7	Very high	27 Å²	27	46.6 Å²	46.6	14%	0.138	24%	0.243	C	C	.	.	H	α-helix	trans	-57.8	-47.6	174.7	-66.9	173.8	0	0	0	110.4	I127 W133 Y177 G178 V183 R184 I185	I127-I181 HydrophobicContact CG1-CD1 4.28Å; I127-I181 HydrophobicContact CG1-CG1 3.76Å; W133-I181 HydrophobicContact CZ3-CG2 4.36Å; Y177-I181 HydrophobicContact CD2-CD1 4.01Å; Y177-I181 PolarHBondContact O-N 3.24Å; G178-I181 PolarHBondContact O-N 3.38Å; I181-V183 PolarHBondContact O-N 3.41Å; I181-R184 WeakPolarHBondContact O-CB 3.48Å; I181-R184 PolarHBondContact O-N 3.36Å; I181-I185 HydrophobicContact CG2-CD1 3.85Å; I181-I185 HydrophobicContact CG2-CG1 4.45Å; I181-I185 WeakPolarHBondContact O-CG1 3.36Å; I181-I185 PolarHBondContact O-N 2.88Å
182	F	96.9	Very high	94.6	Very high	131 Å²	131	43.7 Å²	43.7	58%	0.575	22%	0.223	S	C	*	.	H	α-helix	trans	-59.7	-49	178.9	179.7	-109.7	0	0	0	112.4	G178 C179 V180 R184 I185 L186	G178-F182 PolarHBondContact O-N 2.92Å; C179-F182 PolarHBondContact O-N 3.25Å; V180-F182 VanDerWaalsContact C-N 3.34Å; V180-F182 PolarHBondContact O-N 3.17Å; F182-R184 VanDerWaalsContact C-N 3.28Å; F182-R184 PolarHBondContact O-N 2.93Å; F182-I185 PolarHBondContact O-N 2.88Å; F182-L186 HydrophobicContact CD1-CD1 4.16Å; F182-L186 HydrophobicContact CE1-CD1 3.62Å; F182-L186 HydrophobicContact CE1-CG 4.42Å; F182-L186 HydrophobicContact CE2-CD1 4.49Å; F182-L186 HydrophobicContact CZ-CD1 3.81Å; F182-L186 HydrophobicContact CZ-CD2 4.49Å; F182-L186 HydrophobicContact CZ-CG 4.3Å; F182-L186 WeakPolarHBondContact O-CG 3.23Å; F182-L186 PolarHBondContact O-N 2.86Å; F182-L186 VanDerWaalsContact O-N 3.1Å
183	V	96.7	Very high	94.6	Very high	13 Å²	13	43.8 Å²	43.8	8%	0.079	22%	0.223	C	C	.	.	H	α-helix	trans	-61.7	-38.6	176.7	176.4	0	0	0	0	111	L165 I169 A172 C179 V180 I181 L186 Q187	L165-V183 HydrophobicContact CB-CG1 4.2Å; L165-V183 WeakPolarHBondContact O-CG1 3.29Å; I169-V183 HydrophobicContact CD1-CB 3.88Å; I169-V183 HydrophobicContact CD1-CG1 3.51Å; I169-V183 HydrophobicContact CG1-CG1 4.1Å; A172-V183 HydrophobicContact CB-CG2 4.23Å; C179-V183 WeakPolarHBondContact O-CG2 3.45Å; C179-V183 PolarHBondContact O-N 3.16Å; V180-V183 PolarHBondContact O-N 2.96Å; I181-V183 PolarHBondContact O-N 3.41Å; V183-L186 PolarHBondContact O-N 2.77Å; V183-Q187 WeakPolarHBondContact O-CG 3.3Å; V183-Q187 PolarHBondContact O-N 3.06Å
184	R	95.3	Very high	94.7	Very high	6 Å²	6	43.8 Å²	43.8	2%	0.023	22%	0.222	C	C	.	.	H	α-helix	trans	-65.9	-38.9	177.9	-87.2	-78.1	172.5	176.7	-7.3	113.3	I87 N90 L91 S130 I169 V180 I181 F182 L186 Q187 G188	I87-R184 PolarHBondContact O-NH2 2.84Å; N90-R184 PolarHBondContact OD1-NH2 3.46Å; L91-R184 HydrophobicContact CD2-CG 4.4Å; L91-R184 VanDerWaalsContact CD2-CZ 3.48Å; S130-R184 VanDerWaalsContact OG-CB 3.26Å; S130-R184 WeakPolarHBondContact OG-CB 3.45Å; I169-R184 HydrophobicContact CD1-CG 4.29Å; V180-R184 VanDerWaalsContact O-CB 3.3Å; V180-R184 WeakPolarHBondContact O-CB 3.38Å; V180-R184 WeakPolarHBondContact O-CG 3.31Å; V180-R184 PolarHBondContact O-N 3.02Å; I181-R184 WeakPolarHBondContact O-CB 3.48Å; I181-R184 PolarHBondContact O-N 3.36Å; F182-R184 VanDerWaalsContact C-N 3.28Å; F182-R184 PolarHBondContact O-N 2.93Å; R184-L186 VanDerWaalsContact C-N 3.35Å; R184-Q187 WeakPolarHBondContact O-CB 3.36Å; R184-Q187 PolarHBondContact O-N 3.43Å; R184-G188 PolarHBondContact O-N 2.71Å
185	I	96.3	Very high	94.7	Very high	54 Å²	54	38.3 Å²	38.3	28%	0.277	20%	0.202	S	C	.	.	H	α-helix	trans	-62.6	-45.1	173.5	-68.1	165.2	0	0	0	109.9	S130 W133 I181 F182 Q187 G188 L189	S130-I185 WeakPolarHBondContact O-CG1 3.39Å; W133-I185 HydrophobicContact CE3-CD1 3.98Å; W133-I185 HydrophobicContact CE3-CG1 4.17Å; W133-I185 HydrophobicContact CZ3-CD1 4.31Å; I181-I185 HydrophobicContact CG2-CD1 3.85Å; I181-I185 HydrophobicContact CG2-CG1 4.45Å; I181-I185 WeakPolarHBondContact O-CG1 3.36Å; I181-I185 PolarHBondContact O-N 2.88Å; F182-I185 PolarHBondContact O-N 2.88Å; I185-Q187 VanDerWaalsContact C-N 3.35Å; I185-Q187 PolarHBondContact O-N 2.99Å; I185-G188 PolarHBondContact O-N 2.88Å; I185-L189 PolarHBondContact O-N 3.04Å
186	L	96.8	Very high	94.7	Very high	56 Å²	56	33 Å²	33	29%	0.293	17%	0.169	S	C	.	.	H	α-helix	trans	-61.7	-41.7	176.5	-66.3	179.6	0	0	0	111.9	L165 F182 V183 R184 G188 L189 V190	L165-L186 HydrophobicContact CD1-CB 3.79Å; L165-L186 HydrophobicContact CD2-CB 4.38Å; L165-L186 HydrophobicContact CD2-CD1 4.31Å; F182-L186 HydrophobicContact CD1-CD1 4.16Å; F182-L186 HydrophobicContact CE1-CD1 3.62Å; F182-L186 HydrophobicContact CE1-CG 4.42Å; F182-L186 HydrophobicContact CE2-CD1 4.49Å; F182-L186 HydrophobicContact CZ-CD1 3.81Å; F182-L186 HydrophobicContact CZ-CD2 4.49Å; F182-L186 HydrophobicContact CZ-CG 4.3Å; F182-L186 WeakPolarHBondContact O-CG 3.23Å; F182-L186 PolarHBondContact O-N 2.86Å; F182-L186 VanDerWaalsContact O-N 3.1Å; V183-L186 PolarHBondContact O-N 2.77Å; R184-L186 VanDerWaalsContact C-N 3.35Å; L186-G188 VanDerWaalsContact C-N 3.35Å; L186-G188 PolarHBondContact O-N 3.02Å; L186-L189 PolarHBondContact O-N 3.39Å; L186-V190 WeakPolarHBondContact O-CG2 3.34Å; L186-V190 PolarHBondContact O-N 3.31Å
187	Q	95.8	Very high	94.8	Very high	0 Å²	0	28.5 Å²	28.5	0%	0	15%	0.148	C	C	.	.	H	α-helix	trans	-59	-45.6	173.6	-75.8	-177.4	-52	0	0	111.7	F131 T162 L165 N166 V183 R184 I185 L189 V190 E191	F131-Q187 HydrophobicContact CD2-CB 4.27Å; F131-Q187 HydrophobicContact CE2-CB 4.36Å; T162-Q187 PolarHBondContact O-NE2 3.33Å; L165-Q187 HydrophobicContact CB-CG 3.62Å; L165-Q187 HydrophobicContact CD1-CG 4.08Å; N166-Q187 VanDerWaalsContact CB-NE2 3.3Å; V183-Q187 WeakPolarHBondContact O-CG 3.3Å; V183-Q187 PolarHBondContact O-N 3.06Å; R184-Q187 WeakPolarHBondContact O-CB 3.36Å; R184-Q187 PolarHBondContact O-N 3.43Å; I185-Q187 VanDerWaalsContact C-N 3.35Å; I185-Q187 PolarHBondContact O-N 2.99Å; Q187-L189 VanDerWaalsContact C-N 3.34Å; Q187-L189 PolarHBondContact O-N 3.37Å; Q187-V190 WeakPolarHBondContact O-CG2 3.18Å; Q187-V190 PolarHBondContact O-N 3.1Å; Q187-E191 WeakPolarHBondContact O-CB 3.32Å; Q187-E191 PolarHBondContact O-N 3.48Å
188	G	94.7	Very high	94.9	Very high	0 Å²	0	24.4 Å²	24.4	0%	0	13%	0.133	C	C	.	.	H	α-helix	trans	-59	-44.9	175.7	0	0	0	0	0	112.4	F131 G134 Y135 R184 I185 L186 E191 G192	F131-G188 WeakPolarHBondContact O-CA 3.49Å; G134-G188 VanDerWaalsContact C-C 3.48Å; Y135-G188 VanDerWaalsContact CA-O 3.27Å; Y135-G188 WeakPolarHBondContact CA-O 3.42Å; Y135-G188 PolarHBondContact N-O 3.2Å; R184-G188 PolarHBondContact O-N 2.71Å; I185-G188 PolarHBondContact O-N 2.88Å; L186-G188 VanDerWaalsContact C-N 3.35Å; L186-G188 PolarHBondContact O-N 3.02Å; G188-E191 PolarHBondContact O-N 3.35Å; G188-G192 PolarHBondContact O-N 3.38Å
189	L	95.2	Very high	94.8	Very high	78 Å²	78	23 Å²	23	41%	0.408	12%	0.118	S	C	.	.	H	α-helix	trans	-59.1	-53	178.9	-165.4	165.3	0	0	0	110.6	T138 I185 L186 Q187 E191 G192	T138-L189 VanDerWaalsContact CB-O 3.29Å; T138-L189 WeakPolarHBondContact CB-O 3.29Å; T138-L189 HydrophobicContact CG2-CD2 4.39Å; T138-L189 WeakPolarHBondContact CG2-O 3.41Å; T138-L189 WeakPolarHBondContact OG1-CA 3.28Å; T138-L189 WeakPolarHBondContact OG1-CG 3.4Å; T138-L189 PolarHBondContact OG1-O 3.49Å; I185-L189 PolarHBondContact O-N 3.04Å; L186-L189 PolarHBondContact O-N 3.39Å; Q187-L189 VanDerWaalsContact C-N 3.34Å; Q187-L189 PolarHBondContact O-N 3.37Å; L189-E191 PolarHBondContact O-N 2.89Å; L189-G192 PolarHBondContact O-N 3.29Å
190	V	95.3	Very high	94.6	Very high	27 Å²	27	21 Å²	21	16%	0.164	11%	0.106	C	C	.	.	H	α-helix	trans	-69.5	-32.8	-178.8	-58	0	0	0	0	112.9	A158 L161 L165 L186 Q187 G192 V193	A158-V190 WeakPolarHBondContact CB-O 3.5Å; L161-V190 HydrophobicContact CB-CB 4.2Å; L161-V190 HydrophobicContact CB-CG1 4.14Å; L161-V190 HydrophobicContact CB-CG2 4.2Å; L161-V190 HydrophobicContact CD1-CG1 4.22Å; L165-V190 HydrophobicContact CD1-CG1 4.49Å; L165-V190 HydrophobicContact CD1-CG2 4.08Å; L186-V190 WeakPolarHBondContact O-CG2 3.34Å; L186-V190 PolarHBondContact O-N 3.31Å; Q187-V190 WeakPolarHBondContact O-CG2 3.18Å; Q187-V190 PolarHBondContact O-N 3.1Å; V190-G192 VanDerWaalsContact C-N 3.34Å; V190-V193 WeakPolarHBondContact O-CG1 3.38Å
191	E	94.2	Very high	94.4	Very high	1 Å²	1	21.3 Å²	21.3	1%	0.005	11%	0.107	C	C	.	.	H	α-helix	trans	-78.4	-20.9	-178.5	-164.7	174.2	163.5	0	0	112.4	S84 R88 F131 Y135 Q187 G188 L189 V193 T194	S84-E191 VanDerWaalsContact OG-CG 3.27Å; S84-E191 WeakPolarHBondContact OG-CG 3.27Å; S84-E191 PolarHBondContact OG-OE1 3.47Å; R88-E191 IonicContact CZ-OE1 3.34Å; R88-E191 IonicContact NH1-OE1 2.8Å; R88-E191 VanDerWaalsContact NH2-CD 3.27Å; R88-E191 IonicContact NH2-OE1 3.2Å; R88-E191 PolarHBondContact NH2-OE1 3.3Å; R88-E191 IonicContact NH2-OE2 3.81Å; F131-E191 HydrophobicContact CE2-CB 4.27Å; F131-E191 WeakPolarHBondContact CE2-OE2 3.47Å; F131-E191 HydrophobicContact CZ-CB 4.12Å; F131-E191 HydrophobicContact CZ-CG 4.3Å; F131-E191 WeakPolarHBondContact CZ-OE2 3.3Å; Y135-E191 HydrophobicContact CD2-CB 4.45Å; Y135-E191 HydrophobicContact CE2-CB 4.49Å; Y135-E191 HydrophobicContact CE2-CG 4.37Å; Q187-E191 WeakPolarHBondContact O-CB 3.32Å; Q187-E191 PolarHBondContact O-N 3.48Å; G188-E191 PolarHBondContact O-N 3.35Å; L189-E191 PolarHBondContact O-N 2.89Å; E191-V193 PolarHBondContact O-N 3.41Å; E191-V193 VanDerWaalsContact O-N 3.17Å; E191-T194 VanDerWaalsContact O-CB 3.3Å; E191-T194 WeakPolarHBondContact O-CB 3.32Å; E191-T194 PolarHBondContact O-N 3.21Å; E191-T194 VanDerWaalsContact O-N 3.13Å; E191-T194 PolarHBondContact O-OG1 3.11Å
192	G	92.4	Very high	94.3	Very high	0 Å²	0	20 Å²	20	0%	0	10%	0.1	C	C	.	.	T	Hydrogen-bonded Turn	trans	-58.1	-27.7	179.5	0	0	0	0	0	114.6	Y135 Q139 G188 L189 V190 T194	Y135-G192 VanDerWaalsContact CD2-CA 3.48Å; Q139-G192 PolarHBondContact NE2-O 2.95Å; Q139-G192 PolarHBondContact OE1-O 2.91Å; G188-G192 PolarHBondContact O-N 3.38Å; L189-G192 PolarHBondContact O-N 3.29Å; V190-G192 VanDerWaalsContact C-N 3.34Å; G192-T194 VanDerWaalsContact C-N 3.34Å; G192-T194 PolarHBondContact O-N 3.46Å
193	V	94.8	Very high	93.9	Very high	14 Å²	14	14.1 Å²	14.1	9%	0.085	8%	0.076	C	C	.	.	T	Hydrogen-bonded Turn	trans	-80.8	-11.5	-179.1	73.4	0	0	0	0	114.1	G142 V154 A158 V190 E191 Y195 P196 A197	G142-V193 WeakPolarHBondContact O-CG2 3.33Å; V154-V193 HydrophobicContact CG1-CB 4.28Å; V154-V193 HydrophobicContact CG1-CG1 3.86Å; V154-V193 HydrophobicContact CG1-CG2 3.37Å; A158-V193 HydrophobicContact CB-CG1 3.67Å; V190-V193 WeakPolarHBondContact O-CG1 3.38Å; E191-V193 PolarHBondContact O-N 3.41Å; E191-V193 VanDerWaalsContact O-N 3.17Å; V193-Y195 PolarHBondContact O-N 3.45Å; V193-P196 WeakPolarHBondContact O-CD 3.03Å; V193-A197 VanDerWaalsContact O-CB 3.23Å; V193-A197 WeakPolarHBondContact O-CB 3.27Å; V193-A197 PolarHBondContact O-N 3.13Å
194	T	94.4	Very high	93.3	Very high	2 Å²	2	16.4 Å²	16.4	1%	0.012	9%	0.085	C	C	.	.	H	α-helix	trans	-63.5	-44.2	-168.9	-47.1	0	0	0	0	113	F81 F155 E191 G192 C198	F81-T194 HydrophobicContact CD1-CG2 4.09Å; F81-T194 HydrophobicContact CE1-CG2 3.61Å; F81-T194 HydrophobicContact CZ-CG2 4.06Å; F155-T194 HydrophobicContact CD2-CG2 3.75Å; F155-T194 WeakPolarHBondContact CD2-O 3.47Å; F155-T194 HydrophobicContact CE2-CG2 3.35Å; F155-T194 HydrophobicContact CZ-CG2 4.19Å; E191-T194 VanDerWaalsContact O-CB 3.3Å; E191-T194 WeakPolarHBondContact O-CB 3.32Å; E191-T194 PolarHBondContact O-N 3.21Å; E191-T194 VanDerWaalsContact O-N 3.13Å; E191-T194 PolarHBondContact O-OG1 3.11Å; G192-T194 VanDerWaalsContact C-N 3.34Å; G192-T194 PolarHBondContact O-N 3.46Å; T194-C198 PolarHBondContact O-N 2.69Å; T194-C198 VanDerWaalsContact O-N 3.11Å
195	Y	92.8	Very high	93.1	Very high	28 Å²	28	16.2 Å²	16.2	11%	0.11	8%	0.084	C	C	.	.	H	α-helix	trans	-68.1	-49.8	179.1	-86.7	-89.5	0	0	0	113.5	F81 F85 Y135 V193 A197 C198 H199 F219 S222	F81-Y195 HydrophobicContact CD1-CE2 4.45Å; F81-Y195 HydrophobicContact CE1-CD1 4.25Å; F81-Y195 AromaticContact CE1-CD2 3.92Å; F81-Y195 HydrophobicContact CE1-CD2 3.92Å; F81-Y195 HydrophobicContact CE1-CE1 4.2Å; F81-Y195 AromaticContact CE1-CE2 3.87Å; F81-Y195 HydrophobicContact CE1-CE2 3.87Å; F81-Y195 HydrophobicContact CE1-CG 4.11Å; F81-Y195 HydrophobicContact CZ-CD1 4.31Å; F81-Y195 HydrophobicContact CZ-CE1 4.5Å; F81-Y195 HydrophobicContact CZ-CG 4.37Å; F85-Y195 AromaticContact CE2-CE2 3.72Å; F85-Y195 HydrophobicContact CE2-CE2 3.72Å; F85-Y195 AromaticContact CE2-CZ 3.88Å; F85-Y195 WeakPolarHBondContact CE2-OH 3.35Å; F85-Y195 AromaticContact CZ-CE2 3.94Å; F85-Y195 HydrophobicContact CZ-CE2 3.94Å; F85-Y195 AromaticContact CZ-CZ 3.97Å; F85-Y195 WeakPolarHBondContact CZ-OH 3.37Å; Y135-Y195 WeakPolarHBondContact OH-CD2 3.33Å; Y135-Y195 WeakPolarHBondContact OH-CE2 3.21Å; V193-Y195 PolarHBondContact O-N 3.45Å; Y195-A197 VanDerWaalsContact C-N 3.33Å; Y195-A197 PolarHBondContact O-N 3.13Å; Y195-C198 PolarHBondContact O-N 3.41Å; Y195-H199 PolarHBondContact O-N 3.38Å; Y195-H199 PolarHBondContact O-ND1 3.12Å; Y195-H199 VanDerWaalsContact O-ND1 3.15Å; Y195-F219 HydrophobicContact CD1-CD1 4.08Å; Y195-F219 AromaticContact CD1-CE1 3.62Å; Y195-F219 HydrophobicContact CD1-CE1 3.62Å; Y195-F219 AromaticContact CE1-CD1 3.68Å; Y195-F219 HydrophobicContact CE1-CD1 3.68Å; Y195-F219 AromaticContact CE1-CE1 3.73Å; Y195-F219 HydrophobicContact CE1-CE1 3.73Å; Y195-S222 PolarHBondContact OH-OG 3.41Å; Y195-S222 VanDerWaalsContact OH-OG 3.05Å
196	P	93.4	Very high	92.8	Very high	0 Å²	0	13.6 Å²	13.6	0%	0	7%	0.07	C	C	.	.	H	α-helix	trans	-58.4	-42.1	173.2	-27.2	34.4	0	0	0	113.5	A146 V193 C198 H199 G200 S443	A146-P196 HydrophobicContact CB-CB 4.43Å; V193-P196 WeakPolarHBondContact O-CD 3.03Å; P196-C198 VanDerWaalsContact C-N 3.32Å; P196-C198 PolarHBondContact O-N 2.9Å; P196-H199 PolarHBondContact O-N 3.49Å; P196-G200 PolarHBondContact O-N 3.38Å; P196-S443 WeakPolarHBondContact CB-O 3.44Å; P196-S443 PolarHBondContact O-OG 3.4Å
197	A	94.4	Very high	92.5	Very high	0 Å²	0	11 Å²	11	0%	0	6%	0.057	C	C	.	.	H	α-helix	trans	-62.5	-38.9	178.8	0	0	0	0	0	112.2	A146 V154 F155 V193 Y195 H199 G200 I201	A146-A197 HydrophobicContact CB-CB 4.19Å; V154-A197 HydrophobicContact CB-CB 4.5Å; V154-A197 HydrophobicContact CG1-CB 4.3Å; F155-A197 HydrophobicContact CB-CB 3.94Å; F155-A197 HydrophobicContact CD2-CB 4.29Å; V193-A197 VanDerWaalsContact O-CB 3.23Å; V193-A197 WeakPolarHBondContact O-CB 3.27Å; V193-A197 PolarHBondContact O-N 3.13Å; Y195-A197 VanDerWaalsContact C-N 3.33Å; Y195-A197 PolarHBondContact O-N 3.13Å; A197-H199 VanDerWaalsContact C-N 3.32Å; A197-H199 PolarHBondContact O-N 3.47Å; A197-G200 WeakPolarHBondContact O-CA 3.29Å; A197-G200 PolarHBondContact O-N 3.33Å; A197-G200 VanDerWaalsContact O-N 3.11Å; A197-I201 WeakPolarHBondContact O-CG1 3.36Å; A197-I201 PolarHBondContact O-N 2.99Å
198	C	94.8	Very high	92	Very high	0 Å²	0	12.9 Å²	12.9	0%	0	7%	0.069	C	C	.	.	H	α-helix	trans	-59.7	-41.6	174.8	-172.9	0	0	0	0	112.2	F81 F155 T194 Y195 P196 G200 I201 W202 F219	F81-C198 HydrophobicContact CE2-CB 3.81Å; F81-C198 HydrophobicContact CZ-CB 3.81Å; F155-C198 HydrophobicContact CD2-CB 4.48Å; F155-C198 HydrophobicContact CE2-CB 4.28Å; T194-C198 PolarHBondContact O-N 2.69Å; T194-C198 VanDerWaalsContact O-N 3.11Å; Y195-C198 PolarHBondContact O-N 3.41Å; P196-C198 VanDerWaalsContact C-N 3.32Å; P196-C198 PolarHBondContact O-N 2.9Å; C198-G200 VanDerWaalsContact C-N 3.33Å; C198-G200 PolarHBondContact O-N 2.92Å; C198-I201 WeakPolarHBondContact O-CB 3.31Å; C198-I201 PolarHBondContact O-N 3.28Å; C198-W202 PolarHBondContact O-N 3.15Å; C198-W202 VanDerWaalsContact O-N 3.08Å; C198-W202 PolarHBondContact SG-NE1 3.43Å; C198-F219 HydrophobicContact CB-CE1 4.47Å; C198-F219 HydrophobicContact CB-CZ 4.49Å
199	H	91.8	Very high	91.6	Very high	0 Å²	0	16.2 Å²	16.2	0%	0	9%	0.087	C	C	.	.	H	α-helix	trans	-66.3	-35.4	174.6	-75.6	71.6	0	0	0	112.6	Y195 P196 A197 I201 W202 S203 F219 N431 A442 M446	Y195-H199 PolarHBondContact O-N 3.38Å; Y195-H199 PolarHBondContact O-ND1 3.12Å; Y195-H199 VanDerWaalsContact O-ND1 3.15Å; P196-H199 PolarHBondContact O-N 3.49Å; A197-H199 VanDerWaalsContact C-N 3.32Å; A197-H199 PolarHBondContact O-N 3.47Å; H199-I201 VanDerWaalsContact C-N 3.29Å; H199-I201 PolarHBondContact O-N 3.36Å; H199-W202 PolarHBondContact O-N 3.35Å; H199-S203 PolarHBondContact O-N 3.03Å; H199-F219 AromaticContact CE1-CE2 3.66Å; H199-F219 AromaticContact CE1-CZ 3.18Å; H199-F219 WeakPolarHBondContact CE1-CZ 3.18Å; H199-F219 AromaticContact ND1-CZ 3.73Å; H199-N431 PolarHBondContact NE2-O 3.43Å; H199-A442 HydrophobicContact CB-CB 4.46Å; H199-M446 HydrophobicContact CB-CB 4.44Å; H199-M446 WeakPolarHBondContact CE1-CE 3.06Å; H199-M446 VanDerWaalsContact NE2-CE 3.29Å; H199-M446 WeakPolarHBondContact NE2-CE 3.43Å
200	G	89.8	Confident	91.4	Very high	5 Å²	5	14 Å²	14	5%	0.052	7%	0.074	C	C	.	.	H	α-helix	trans	-64.8	-29	172.5	0	0	0	0	0	113.9	P196 A197 C198 S203 S443	P196-G200 PolarHBondContact O-N 3.38Å; A197-G200 WeakPolarHBondContact O-CA 3.29Å; A197-G200 PolarHBondContact O-N 3.33Å; A197-G200 VanDerWaalsContact O-N 3.11Å; C198-G200 VanDerWaalsContact C-N 3.33Å; C198-G200 PolarHBondContact O-N 2.92Å; G200-S203 PolarHBondContact O-OG 3.45Å; G200-S443 WeakPolarHBondContact CA-OG 3.37Å; G200-S443 PolarHBondContact N-OG 2.96Å
201	I	92.3	Very high	91.1	Very high	5 Å²	5	13.7 Å²	13.7	3%	0.026	7%	0.07	C	C	.	.	H	α-helix	trans	-70.5	-48.5	171	-63.9	166	0	0	0	109.3	I73 A151 N152 F155 A197 C198 H199 S203 K204 W205 W260	I73-I201 HydrophobicContact CG2-CG2 3.96Å; A151-I201 HydrophobicContact CB-CG1 4.05Å; N152-I201 HydrophobicContact CB-CG1 4.43Å; F155-I201 HydrophobicContact CB-CD1 4.07Å; F155-I201 HydrophobicContact CD1-CD1 4.49Å; F155-I201 HydrophobicContact CG-CD1 4.2Å; A197-I201 WeakPolarHBondContact O-CG1 3.36Å; A197-I201 PolarHBondContact O-N 2.99Å; C198-I201 WeakPolarHBondContact O-CB 3.31Å; C198-I201 PolarHBondContact O-N 3.28Å; H199-I201 VanDerWaalsContact C-N 3.29Å; H199-I201 PolarHBondContact O-N 3.36Å; I201-S203 VanDerWaalsContact C-N 3.3Å; I201-S203 PolarHBondContact O-N 3.25Å; I201-K204 PolarHBondContact O-N 3.26Å; I201-K204 VanDerWaalsContact O-N 3.15Å; I201-W205 HydrophobicContact CG2-CG 4.41Å; I201-W205 WeakPolarHBondContact O-CB 3.14Å; I201-W205 PolarHBondContact O-N 3.27Å; I201-W260 HydrophobicContact CD1-CH2 3.99Å; I201-W260 HydrophobicContact CD1-CZ2 3.95Å
202	W	92.6	Very high	90.9	Very high	0 Å²	0	13.6 Å²	13.6	0%	0	7%	0.07	C	C	.	.	H	α-helix	trans	-68.9	-24.5	-177	-62.7	126.2	0	0	0	114.5	I73 A74 C198 H199 K204 W205 A206 L214 S218 L435	I73-W202 HydrophobicContact CB-CH2 4.45Å; I73-W202 HydrophobicContact CG2-CH2 4Å; A74-W202 VanDerWaalsContact CA-CH2 3.47Å; A74-W202 HydrophobicContact CB-CH2 3.55Å; A74-W202 HydrophobicContact CB-CZ2 3.95Å; C198-W202 PolarHBondContact O-N 3.15Å; C198-W202 VanDerWaalsContact O-N 3.08Å; C198-W202 PolarHBondContact SG-NE1 3.43Å; H199-W202 PolarHBondContact O-N 3.35Å; W202-K204 PolarHBondContact O-N 3.01Å; W202-W205 HydrophobicContact CE3-CB 4.13Å; W202-W205 HydrophobicContact CZ3-CB 4.16Å; W202-A206 HydrophobicContact CB-CB 4.14Å; W202-A206 HydrophobicContact CE3-CB 3.9Å; W202-A206 WeakPolarHBondContact O-CB 3.18Å; W202-A206 PolarHBondContact O-N 3.44Å; W202-A206 VanDerWaalsContact O-N 3.07Å; W202-L214 HydrophobicContact CD2-CB 4.45Å; W202-L214 HydrophobicContact CE3-CB 4.04Å; W202-L214 HydrophobicContact CE3-CD1 4.34Å; W202-L214 HydrophobicContact CH2-CB 4.27Å; W202-L214 HydrophobicContact CZ3-CB 3.92Å; W202-L214 HydrophobicContact CZ3-CD1 4.12Å; W202-L214 HydrophobicContact CZ3-CG 4.43Å; W202-S218 WeakPolarHBondContact CZ2-OG 3.39Å; W202-L435 HydrophobicContact CB-CD1 3.97Å; W202-L435 HydrophobicContact CB-CD2 4.21Å
203	S	87.5	Confident	90.9	Very high	8 Å²	8	18 Å²	18	6%	0.056	9%	0.086	C	C	.	.	H	α-helix	trans	-62.5	-22.4	173.5	68.4	0	0	0	0	113.2	H199 G200 I201 P439	H199-S203 PolarHBondContact O-N 3.03Å; G200-S203 PolarHBondContact O-OG 3.45Å; I201-S203 VanDerWaalsContact C-N 3.3Å; I201-S203 PolarHBondContact O-N 3.25Å; S203-P439 WeakPolarHBondContact CB-O 3.34Å
204	K	85.3	Confident	90.9	Very high	61 Å²	61	17.3 Å²	17.3	27%	0.265	8%	0.082	S	C	.	.	H	α-helix	trans	-107.8	-27.6	178.4	-64.5	-175.4	-179.5	-174.1	0	114.4	I201 W202 I286 L293	I201-K204 PolarHBondContact O-N 3.26Å; I201-K204 VanDerWaalsContact O-N 3.15Å; W202-K204 PolarHBondContact O-N 3.01Å; K204-I286 VanDerWaalsContact O-CD1 3.26Å; K204-I286 WeakPolarHBondContact O-CD1 3.32Å; K204-L293 HydrophobicContact CG-CD1 4.07Å
205	W	90.4	Very high	90.8	Very high	1 Å²	1	17.2 Å²	17.2	0%	0.004	8%	0.082	C	C	.	.	H	α-helix	trans	-105	-15.7	-171.7	-80.9	90.7	0	0	0	114.8	R69 R70 I73 I201 W202 P207 Y265 P268 H271 I274 I282	R69-W205 HydrophobicContact CB-CZ3 4.2Å; R70-W205 HydrophobicContact CB-CE3 4.26Å; I73-W205 HydrophobicContact CD1-CD2 3.58Å; I73-W205 HydrophobicContact CD1-CE3 3.58Å; I73-W205 HydrophobicContact CD1-CG 4.39Å; I73-W205 HydrophobicContact CD1-CH2 3.49Å; I73-W205 VanDerWaalsContact CD1-CH2 3.49Å; I73-W205 HydrophobicContact CD1-CZ2 3.47Å; I73-W205 VanDerWaalsContact CD1-CZ2 3.47Å; I73-W205 HydrophobicContact CD1-CZ3 3.54Å; I201-W205 HydrophobicContact CG2-CG 4.41Å; I201-W205 WeakPolarHBondContact O-CB 3.14Å; I201-W205 PolarHBondContact O-N 3.27Å; W202-W205 HydrophobicContact CE3-CB 4.13Å; W202-W205 HydrophobicContact CZ3-CB 4.16Å; W205-P207 WeakPolarHBondContact O-CD 3.36Å; W205-Y265 PolarHBondContact NE1-O 3.44Å; W205-P268 HydrophobicContact CD2-CG 4.16Å; W205-P268 HydrophobicContact CE3-CG 4.21Å; W205-P268 HydrophobicContact CZ3-CG 4.45Å; W205-H271 HydrophobicContact CH2-CB 4.12Å; W205-H271 AromaticContact CH2-CD2 3.61Å; W205-I274 HydrophobicContact CH2-CD1 4.41Å; W205-I274 HydrophobicContact CZ3-CD1 4.19Å; W205-I282 HydrophobicContact CE3-CD1 4.45Å
206	A	90.5	Very high	90.8	Very high	0 Å²	0	16 Å²	16	0%	0	8%	0.077	C	C	.	.			trans	-106.8	110.7	-175.3	0	0	0	0	0	113.1	W202 R211 L214	W202-A206 HydrophobicContact CB-CB 4.14Å; W202-A206 HydrophobicContact CE3-CB 3.9Å; W202-A206 WeakPolarHBondContact O-CB 3.18Å; W202-A206 PolarHBondContact O-N 3.44Å; W202-A206 VanDerWaalsContact O-N 3.07Å; A206-R211 HydrophobicContact CB-CB 4.44Å; A206-R211 HydrophobicContact CB-CG 3.68Å; A206-R211 PolarHBondContact O-NE 3.41Å; A206-L214 HydrophobicContact CB-CD1 3.82Å
207	P	90.1	Very high	90.9	Very high	1 Å²	1	17.5 Å²	17.5	1%	0.006	9%	0.086	C	C	.	.			trans	-53.9	142.4	167	-28.1	36.7	0	0	0	111.9	W205 L209 E210 R211 Y281 I282 S285	W205-P207 WeakPolarHBondContact O-CD 3.36Å; P207-L209 PolarHBondContact O-N 3.39Å; P207-E210 PolarHBondContact O-N 2.8Å; P207-R211 WeakPolarHBondContact O-CG 3.03Å; P207-R211 PolarHBondContact O-N 2.93Å; P207-R211 VanDerWaalsContact O-N 3.08Å; P207-Y281 HydrophobicContact CB-CE1 4.18Å; P207-Y281 HydrophobicContact CG-CD1 4.21Å; P207-Y281 HydrophobicContact CG-CE1 3.7Å; P207-I282 HydrophobicContact CG-CG1 4.15Å; P207-S285 WeakPolarHBondContact CB-OG 3.28Å
208	P	85.9	Confident	90.9	Very high	40 Å²	40	17.5 Å²	17.5	26%	0.26	9%	0.086	S	C	.	.	T	Hydrogen-bonded Turn	trans	-52	-33.7	-174.9	-29.2	35.2	0	0	0	115.8	S285 R374	P208-S285 VanDerWaalsContact CD-O 3.27Å; P208-S285 WeakPolarHBondContact CD-O 3.48Å; P208-S285 WeakPolarHBondContact CG-O 3.4Å; P208-R374 PolarHBondContact O-NH1 3.08Å; P208-R374 PolarHBondContact O-NH2 3.01Å
209	L	86.5	Confident	90.8	Very high	70 Å²	70	17.7 Å²	17.7	37%	0.366	9%	0.087	S	C	.	.	T	Hydrogen-bonded Turn	trans	-83.8	-13.6	-179.7	-66.2	179.2	0	0	0	114.4	P207 D371 R374	P207-L209 PolarHBondContact O-N 3.39Å; L209-D371 VanDerWaalsContact O-CB 3.29Å; L209-D371 WeakPolarHBondContact O-CB 3.34Å; L209-R374 HydrophobicContact CD2-CB 4.42Å
210	E	89.4	Confident	90.8	Very high	32 Å²	32	18.7 Å²	18.7	15%	0.15	9%	0.094	C	C	.	.	T	Hydrogen-bonded Turn	trans	-112.3	-0.7	178.6	-61.5	-169.2	-169.8	0	0	113	R70 Y71 P207 S212 R213 L214 D371	R70-E210 IonicContact CZ-OE1 3.18Å; R70-E210 IonicContact CZ-OE2 3.67Å; R70-E210 IonicContact NE-OE1 2.95Å; R70-E210 IonicContact NE-OE2 3.21Å; R70-E210 PolarHBondContact NE-OE2 2.9Å; R70-E210 IonicContact NH2-OE1 3.9Å; R70-E210 PolarHBondContact NH2-OE1 3.07Å; R70-E210 IonicContact NH2-OE2 2.53Å; R70-E210 PolarHBondContact NH2-OE2 2.72Å; Y71-E210 PolarHBondContact OH-OE2 2.78Å; Y71-E210 VanDerWaalsContact OH-OE2 3.13Å; P207-E210 PolarHBondContact O-N 2.8Å; E210-S212 VanDerWaalsContact C-N 3.29Å; E210-S212 PolarHBondContact O-N 2.84Å; E210-R213 PolarHBondContact O-N 2.86Å; E210-L214 HydrophobicContact CB-CD1 4.32Å; E210-L214 WeakPolarHBondContact O-CG 3.31Å; E210-L214 PolarHBondContact O-N 3.48Å; E210-L214 VanDerWaalsContact O-N 3.1Å; E210-D371 WeakPolarHBondContact CA-OD2 3.44Å
211	R	89.6	Confident	91	Very high	19 Å²	19	18.7 Å²	18.7	7%	0.072	9%	0.094	C	C	.	.	H	α-helix	trans	-53.4	-43.7	-176.9	-84.2	173.6	-171.6	175.9	-0.2	113	A206 P207 A215 V432 L435 D436	A206-R211 HydrophobicContact CB-CB 4.44Å; A206-R211 HydrophobicContact CB-CG 3.68Å; A206-R211 PolarHBondContact O-NE 3.41Å; P207-R211 WeakPolarHBondContact O-CG 3.03Å; P207-R211 PolarHBondContact O-N 2.93Å; P207-R211 VanDerWaalsContact O-N 3.08Å; R211-A215 WeakPolarHBondContact O-CB 3.18Å; R211-A215 PolarHBondContact O-N 2.98Å; R211-V432 HydrophobicContact CB-CG1 4.18Å; R211-L435 PolarHBondContact NH1-O 2.97Å; R211-D436 IonicContact NH1-OD1 3.36Å; R211-D436 PolarHBondContact NH1-OD1 3.42Å
212	S	90.8	Very high	90.9	Very high	0 Å²	0	18.5 Å²	18.5	0%	0	9%	0.093	C	C	.	.	H	α-helix	trans	-67.7	-45.1	-175.1	-36.9	0	0	0	0	110.2	E210 T216 D371 R385	E210-S212 VanDerWaalsContact C-N 3.29Å; E210-S212 PolarHBondContact O-N 2.84Å; S212-T216 WeakPolarHBondContact O-CB 3.28Å; S212-T216 VanDerWaalsContact O-CG2 3.23Å; S212-T216 WeakPolarHBondContact O-CG2 3.27Å; S212-T216 PolarHBondContact O-N 3.1Å; S212-T216 PolarHBondContact O-OG1 3.47Å; S212-D371 WeakPolarHBondContact CB-OD1 3.31Å; S212-D371 WeakPolarHBondContact CB-OD2 3.44Å; S212-D371 PolarHBondContact N-OD2 2.85Å; S212-D371 VanDerWaalsContact N-OD2 3.14Å; S212-D371 PolarHBondContact OG-OD1 3.41Å; S212-R385 PolarHBondContact OG-NH1 2.89Å; S212-R385 PolarHBondContact OG-NH2 2.81Å; S212-R385 VanDerWaalsContact OG-NH2 3.09Å
213	R	92.7	Very high	90.7	Very high	92 Å²	92	19.5 Å²	19.5	35%	0.347	10%	0.097	S	C	.	.	H	α-helix	trans	-60.4	-47.7	179.5	-179.2	178	177.7	172.2	4.4	112.2	Y71 E210 T216 T217 Q368 D371	Y71-R213 HydrophobicContact CE1-CG 4.21Å; Y71-R213 VanDerWaalsContact OH-CD 3.29Å; Y71-R213 WeakPolarHBondContact OH-CD 3.22Å; Y71-R213 VanDerWaalsContact OH-CZ 3.32Å; Y71-R213 PolarHBondContact OH-NE 2.86Å; Y71-R213 PolarHBondContact OH-NH1 3.5Å; E210-R213 PolarHBondContact O-N 2.86Å; R213-T216 PolarHBondContact O-OG1 3.1Å; R213-T217 WeakPolarHBondContact O-CB 3.49Å; R213-T217 PolarHBondContact O-N 3.44Å; R213-T217 VanDerWaalsContact O-N 3.09Å; R213-T217 PolarHBondContact O-OG1 3.05Å; R213-Q368 VanDerWaalsContact CD-OE1 3.22Å; R213-D371 VanDerWaalsContact CB-OD2 3.31Å; R213-D371 WeakPolarHBondContact CB-OD2 3.49Å; R213-D371 PolarHBondContact N-OD2 3.4Å
214	L	93.7	Very high	90.9	Very high	0 Å²	0	20.1 Å²	20.1	0%	0	10%	0.103	C	C	.	.	H	α-helix	trans	-69	-43.6	-179.4	-64.2	171.6	0	0	0	111.8	R70 Y71 A74 W202 A206 E210 T217 S218	R70-L214 HydrophobicContact CB-CD1 4.4Å; R70-L214 HydrophobicContact CG-CD1 4.36Å; R70-L214 HydrophobicContact CG-CD2 4.29Å; Y71-L214 HydrophobicContact CD1-CD2 3.72Å; Y71-L214 HydrophobicContact CD2-CD2 4.47Å; Y71-L214 HydrophobicContact CE1-CD2 3.63Å; Y71-L214 HydrophobicContact CE2-CD2 4.4Å; Y71-L214 HydrophobicContact CG-CD2 4.13Å; A74-L214 HydrophobicContact CB-CD2 4.03Å; W202-L214 HydrophobicContact CD2-CB 4.45Å; W202-L214 HydrophobicContact CE3-CB 4.04Å; W202-L214 HydrophobicContact CE3-CD1 4.34Å; W202-L214 HydrophobicContact CH2-CB 4.27Å; W202-L214 HydrophobicContact CZ3-CB 3.92Å; W202-L214 HydrophobicContact CZ3-CD1 4.12Å; W202-L214 HydrophobicContact CZ3-CG 4.43Å; A206-L214 HydrophobicContact CB-CD1 3.82Å; E210-L214 HydrophobicContact CB-CD1 4.32Å; E210-L214 WeakPolarHBondContact O-CG 3.31Å; E210-L214 PolarHBondContact O-N 3.48Å; E210-L214 VanDerWaalsContact O-N 3.1Å; L214-T217 PolarHBondContact O-N 2.88Å; L214-S218 PolarHBondContact O-N 3.28Å; L214-S218 VanDerWaalsContact O-N 3.14Å; L214-S218 PolarHBondContact O-OG 2.85Å
215	A	92.7	Very high	91.1	Very high	0 Å²	0	17.3 Å²	17.3	0%	0	9%	0.091	C	C	.	.	H	α-helix	trans	-64.4	-47.1	178	0	0	0	0	0	111.6	R211 T217 S218 F219 V432	R211-A215 WeakPolarHBondContact O-CB 3.18Å; R211-A215 PolarHBondContact O-N 2.98Å; A215-T217 VanDerWaalsContact C-N 3.34Å; A215-T217 PolarHBondContact O-N 3.27Å; A215-S218 WeakPolarHBondContact O-CB 3.37Å; A215-S218 PolarHBondContact O-N 3.48Å; A215-F219 HydrophobicContact CB-CD2 4.32Å; A215-F219 HydrophobicContact CB-CE2 4.03Å; A215-F219 WeakPolarHBondContact O-CD2 3.47Å; A215-F219 PolarHBondContact O-N 2.92Å; A215-V432 HydrophobicContact CB-CG2 4.12Å
216	T	93.3	Very high	90.8	Very high	1 Å²	1	17.7 Å²	17.7	1%	0.006	9%	0.094	C	C	.	.	H	α-helix	trans	-67.8	-33	180	59.4	0	0	0	0	112.9	S212 R213 S218 F219 C220 V363	S212-T216 WeakPolarHBondContact O-CB 3.28Å; S212-T216 VanDerWaalsContact O-CG2 3.23Å; S212-T216 WeakPolarHBondContact O-CG2 3.27Å; S212-T216 PolarHBondContact O-N 3.1Å; S212-T216 PolarHBondContact O-OG1 3.47Å; R213-T216 PolarHBondContact O-OG1 3.1Å; T216-S218 PolarHBondContact O-N 3.3Å; T216-F219 PolarHBondContact O-N 2.91Å; T216-C220 WeakPolarHBondContact O-CB 3.5Å; T216-C220 PolarHBondContact O-N 3.42Å; T216-V363 WeakPolarHBondContact CB-O 3.45Å; T216-V363 HydrophobicContact CG2-CG1 4.15Å
217	T	94.4	Very high	90.6	Very high	32 Å²	32	18.9 Å²	18.9	20%	0.196	10%	0.101	C	C	.	.	H	α-helix	trans	-63.7	-31.4	171.5	-58.3	0	0	0	0	111.6	A74 I75 R213 L214 A215 C220	A74-T217 HydrophobicContact CB-CG2 4.26Å; I75-T217 HydrophobicContact CG1-CG2 4.39Å; R213-T217 WeakPolarHBondContact O-CB 3.49Å; R213-T217 PolarHBondContact O-N 3.44Å; R213-T217 VanDerWaalsContact O-N 3.09Å; R213-T217 PolarHBondContact O-OG1 3.05Å; L214-T217 PolarHBondContact O-N 2.88Å; A215-T217 VanDerWaalsContact C-N 3.34Å; A215-T217 PolarHBondContact O-N 3.27Å; T217-C220 PolarHBondContact O-SG 3.07Å
218	S	94.8	Very high	90.6	Very high	0 Å²	0	23 Å²	23	0%	0	12%	0.122	C	C	.	.	H	α-helix	trans	-76.7	-45.2	175.1	-54	0	0	0	0	111.7	A74 G78 F81 W202 L214 A215 T216 C220 G221	A74-S218 PolarHBondContact O-OG 2.72Å; G78-S218 VanDerWaalsContact CA-O 3.31Å; G78-S218 WeakPolarHBondContact CA-O 3.38Å; F81-S218 WeakPolarHBondContact CD2-O 3.49Å; W202-S218 WeakPolarHBondContact CZ2-OG 3.39Å; L214-S218 PolarHBondContact O-N 3.28Å; L214-S218 VanDerWaalsContact O-N 3.14Å; L214-S218 PolarHBondContact O-OG 2.85Å; A215-S218 WeakPolarHBondContact O-CB 3.37Å; A215-S218 PolarHBondContact O-N 3.48Å; T216-S218 PolarHBondContact O-N 3.3Å; S218-C220 PolarHBondContact O-N 3.45Å; S218-G221 PolarHBondContact O-N 3.43Å
219	F	91.9	Very high	90.5	Very high	4 Å²	4	21.1 Å²	21.1	2%	0.018	11%	0.11	C	C	.	.	H	α-helix	trans	-75.6	-22.7	-176.2	-66	-53.9	0	0	0	114.5	F81 Y195 C198 H199 A215 T216 G221 S222 N431	F81-F219 HydrophobicContact CE2-CD1 4.11Å; F81-F219 AromaticContact CE2-CE1 3.93Å; F81-F219 HydrophobicContact CE2-CE1 3.93Å; F81-F219 HydrophobicContact CZ-CD1 4.21Å; F81-F219 AromaticContact CZ-CE1 3.84Å; F81-F219 HydrophobicContact CZ-CE1 3.84Å; Y195-F219 HydrophobicContact CD1-CD1 4.08Å; Y195-F219 AromaticContact CD1-CE1 3.62Å; Y195-F219 HydrophobicContact CD1-CE1 3.62Å; Y195-F219 AromaticContact CE1-CD1 3.68Å; Y195-F219 HydrophobicContact CE1-CD1 3.68Å; Y195-F219 AromaticContact CE1-CE1 3.73Å; Y195-F219 HydrophobicContact CE1-CE1 3.73Å; C198-F219 HydrophobicContact CB-CE1 4.47Å; C198-F219 HydrophobicContact CB-CZ 4.49Å; H199-F219 AromaticContact CE1-CE2 3.66Å; H199-F219 AromaticContact CE1-CZ 3.18Å; H199-F219 WeakPolarHBondContact CE1-CZ 3.18Å; H199-F219 AromaticContact ND1-CZ 3.73Å; A215-F219 HydrophobicContact CB-CD2 4.32Å; A215-F219 HydrophobicContact CB-CE2 4.03Å; A215-F219 WeakPolarHBondContact O-CD2 3.47Å; A215-F219 PolarHBondContact O-N 2.92Å; T216-F219 PolarHBondContact O-N 2.91Å; F219-G221 PolarHBondContact O-N 2.9Å; F219-S222 WeakPolarHBondContact O-CB 3.38Å; F219-S222 PolarHBondContact O-N 3.1Å; F219-S222 VanDerWaalsContact O-N 3.11Å; F219-N431 WeakPolarHBondContact CD2-ND2 3.21Å; F219-N431 WeakPolarHBondContact CE2-ND2 3.4Å
220	C	93.2	Very high	90.2	Very high	22 Å²	22	21.2 Å²	21.2	15%	0.149	11%	0.11	C	C	.	.	H	α-helix	trans	-60.9	-26.4	174	73	0	0	0	0	111.8	T216 T217 S218 S222 Y223 A224 V363 P364	T216-C220 WeakPolarHBondContact O-CB 3.5Å; T216-C220 PolarHBondContact O-N 3.42Å; T217-C220 PolarHBondContact O-SG 3.07Å; S218-C220 PolarHBondContact O-N 3.45Å; C220-S222 VanDerWaalsContact C-N 3.27Å; C220-S222 PolarHBondContact O-N 3.4Å; C220-Y223 PolarHBondContact O-N 3.19Å; C220-A224 PolarHBondContact O-N 3.33Å; C220-V363 HydrophobicContact CB-CG1 4.38Å; C220-P364 HydrophobicContact CB-CG 3.63Å
221	G	92.9	Very high	89.9	Confident	5 Å²	5	23 Å²	23	5%	0.052	12%	0.124	C	C	.	.	H	α-helix	trans	-53.9	-39.1	172.5	0	0	0	0	0	113.8	G78 C82 S218 F219 Y223 A224 G225	G78-G221 VanDerWaalsContact O-CA 3.26Å; G78-G221 WeakPolarHBondContact O-CA 3.42Å; C82-G221 WeakPolarHBondContact CA-O 3.44Å; C82-G221 WeakPolarHBondContact CB-O 3.04Å; C82-G221 PolarHBondContact N-O 3.17Å; S218-G221 PolarHBondContact O-N 3.43Å; F219-G221 PolarHBondContact O-N 2.9Å; G221-Y223 VanDerWaalsContact C-N 3.31Å; G221-Y223 PolarHBondContact O-N 3.32Å; G221-A224 PolarHBondContact O-N 3.03Å; G221-G225 PolarHBondContact O-N 3.18Å
222	S	90.5	Very high	89.8	Confident	1 Å²	1	24.8 Å²	24.8	1%	0.007	13%	0.134	C	C	.	.	H	α-helix	trans	-60.4	-40.7	179	-59.7	0	0	0	0	112.5	F81 F85 Y195 F219 C220 A226	F81-S222 WeakPolarHBondContact CD1-OG 3.42Å; F85-S222 WeakPolarHBondContact CB-O 3.2Å; F85-S222 WeakPolarHBondContact CD1-O 3.45Å; F85-S222 VanDerWaalsContact CE2-CB 3.44Å; F85-S222 VanDerWaalsContact CE2-OG 3.24Å; F85-S222 WeakPolarHBondContact CE2-OG 3.27Å; F85-S222 WeakPolarHBondContact CG-O 3.47Å; Y195-S222 PolarHBondContact OH-OG 3.41Å; Y195-S222 VanDerWaalsContact OH-OG 3.05Å; F219-S222 WeakPolarHBondContact O-CB 3.38Å; F219-S222 PolarHBondContact O-N 3.1Å; F219-S222 VanDerWaalsContact O-N 3.11Å; C220-S222 VanDerWaalsContact C-N 3.27Å; C220-S222 PolarHBondContact O-N 3.4Å; S222-A226 PolarHBondContact O-N 2.92Å
223	Y	89.8	Confident	89.4	Confident	20 Å²	20	24.8 Å²	24.8	8%	0.078	13%	0.134	C	C	.	.	H	α-helix	trans	-78.6	-39.9	179.3	-53.8	-65.8	0	0	0	111.4	C220 G221 G225 A226 V227 R322 F326 M359 T360 V363 I427	C220-Y223 PolarHBondContact O-N 3.19Å; G221-Y223 VanDerWaalsContact C-N 3.31Å; G221-Y223 PolarHBondContact O-N 3.32Å; Y223-G225 VanDerWaalsContact C-N 3.25Å; Y223-G225 PolarHBondContact O-N 3.2Å; Y223-A226 PolarHBondContact O-N 2.72Å; Y223-V227 WeakPolarHBondContact O-CG2 3.34Å; Y223-V227 PolarHBondContact O-N 2.91Å; Y223-V227 VanDerWaalsContact O-N 3.12Å; Y223-R322 PolarHBondContact OH-NH2 3.02Å; Y223-F326 HydrophobicContact CD1-CE2 4.28Å; Y223-F326 HydrophobicContact CE1-CD2 4.44Å; Y223-F326 AromaticContact CE1-CE2 3.85Å; Y223-F326 HydrophobicContact CE1-CE2 3.85Å; Y223-F326 HydrophobicContact CE1-CZ 4.43Å; Y223-M359 HydrophobicContact CD1-CG 4.46Å; Y223-M359 HydrophobicContact CD1-SD 3.71Å; Y223-M359 HydrophobicContact CD2-CG 4.29Å; Y223-M359 HydrophobicContact CD2-SD 4.28Å; Y223-M359 HydrophobicContact CE1-CE 3.96Å; Y223-M359 HydrophobicContact CE1-SD 3.37Å; Y223-M359 WeakPolarHBondContact CE1-SD 3.09Å; Y223-M359 HydrophobicContact CE2-CE 3.9Å; Y223-M359 HydrophobicContact CE2-CG 4.34Å; Y223-M359 HydrophobicContact CE2-SD 4Å; Y223-M359 HydrophobicContact CG-CG 4.34Å; Y223-M359 HydrophobicContact CG-SD 4.15Å; Y223-M359 VanDerWaalsContact CZ-CE 3.47Å; Y223-M359 VanDerWaalsContact CZ-SD 3.51Å; Y223-M359 WeakPolarHBondContact OH-CE 3.36Å; Y223-T360 VanDerWaalsContact CB-OG1 3.24Å; Y223-T360 WeakPolarHBondContact CB-OG1 3.29Å; Y223-V363 HydrophobicContact CD2-CG2 4.41Å; Y223-V363 HydrophobicContact CE2-CG2 4.09Å; Y223-I427 WeakPolarHBondContact OH-CD1 3.24Å
224	A	91.1	Very high	88.9	Confident	22 Å²	22	21.8 Å²	21.8	18%	0.182	13%	0.132	C	C	.	.	H	α-helix	trans	-57.1	-41.9	173.6	0	0	0	0	0	111.5	C220 G221 A226 V227 I228 T360	C220-A224 PolarHBondContact O-N 3.33Å; G221-A224 PolarHBondContact O-N 3.03Å; A224-A226 PolarHBondContact O-N 3.23Å; A224-V227 PolarHBondContact O-N 3.28Å; A224-I228 WeakPolarHBondContact O-CB 3.48Å; A224-I228 VanDerWaalsContact O-CG1 3.29Å; A224-I228 WeakPolarHBondContact O-CG1 3.42Å; A224-I228 PolarHBondContact O-N 3.26Å; A224-T360 HydrophobicContact CB-CG2 3.75Å; A224-T360 PolarHBondContact N-OG1 3.49Å
225	G	89.5	Confident	88.4	Confident	1 Å²	1	26.2 Å²	26.2	1%	0.01	16%	0.155	C	C	.	.	H	α-helix	trans	-57.9	-46.7	176.7	0	0	0	0	0	112.7	C82 G221 Y223 V227 I228 A229	C82-G225 VanDerWaalsContact O-CA 3.3Å; C82-G225 WeakPolarHBondContact O-CA 3.38Å; C82-G225 WeakPolarHBondContact SG-CA 3.21Å; G221-G225 PolarHBondContact O-N 3.18Å; Y223-G225 VanDerWaalsContact C-N 3.25Å; Y223-G225 PolarHBondContact O-N 3.2Å; G225-V227 PolarHBondContact O-N 2.84Å; G225-I228 PolarHBondContact O-N 2.86Å; G225-A229 WeakPolarHBondContact O-CB 3.43Å; G225-A229 PolarHBondContact O-N 3.47Å
226	A	83.8	Confident	88.2	Confident	9 Å²	9	27.5 Å²	27.5	7%	0.074	16%	0.162	C	C	.	.	H	α-helix	trans	-62.8	-42.5	177.3	0	0	0	0	0	112.3	S222 Y223 A224 A229	S222-A226 PolarHBondContact O-N 2.92Å; Y223-A226 PolarHBondContact O-N 2.72Å; A224-A226 PolarHBondContact O-N 3.23Å; A226-A229 PolarHBondContact O-N 2.96Å
227	V	87.1	Confident	87.7	Confident	25 Å²	25	28.1 Å²	28.1	15%	0.152	17%	0.166	C	C	.	.	H	α-helix	trans	-64.6	-42.8	179.3	174.3	0	0	0	0	111.8	Y223 A224 G225 P231 H356 L357	Y223-V227 WeakPolarHBondContact O-CG2 3.34Å; Y223-V227 PolarHBondContact O-N 2.91Å; Y223-V227 VanDerWaalsContact O-N 3.12Å; A224-V227 PolarHBondContact O-N 3.28Å; G225-V227 PolarHBondContact O-N 2.84Å; V227-P231 WeakPolarHBondContact O-CD 3.4Å; V227-H356 HydrophobicContact CG2-CB 3.51Å; V227-L357 HydrophobicContact CG1-CB 4.27Å; V227-L357 HydrophobicContact CG1-CD1 4.34Å; V227-L357 HydrophobicContact CG2-CB 4.2Å
228	I	88.3	Confident	87	Confident	88 Å²	88	31.2 Å²	31.2	45%	0.451	18%	0.178	S	C	.	.	H	α-helix	trans	-75.2	-34.2	-179.4	-65.3	167.3	0	0	0	110.8	A224 G225 P231 L232	A224-I228 WeakPolarHBondContact O-CB 3.48Å; A224-I228 VanDerWaalsContact O-CG1 3.29Å; A224-I228 WeakPolarHBondContact O-CG1 3.42Å; A224-I228 PolarHBondContact O-N 3.26Å; G225-I228 PolarHBondContact O-N 2.86Å; I228-P231 WeakPolarHBondContact O-CD 3.42Å; I228-L232 WeakPolarHBondContact O-CB 3.5Å; I228-L232 PolarHBondContact O-N 3.46Å
229	A	84.1	Confident	86.4	Confident	0 Å²	0	39 Å²	39	0%	0	21%	0.208	C	C	.	.	H	α-helix	trans	-71.3	-38.6	-170.6	0	0	0	0	0	115	C89 G225 A226 A233 Y249	C89-A229 HydrophobicContact CB-CB 4.06Å; G225-A229 WeakPolarHBondContact O-CB 3.43Å; G225-A229 PolarHBondContact O-N 3.47Å; A226-A229 PolarHBondContact O-N 2.96Å; A229-A233 WeakPolarHBondContact O-CB 3.47Å; A229-A233 PolarHBondContact O-N 3.42Å; A229-Y249 WeakPolarHBondContact CA-OH 3.33Å; A229-Y249 WeakPolarHBondContact CB-OH 3.49Å
230	M	80.6	Confident	86	Confident	73 Å²	73	43.4 Å²	43.4	36%	0.36	24%	0.236	S	C	.	.	H	α-helix	trans	-64.3	-50.3	-178.6	-61.5	179.2	174.3	0	0	112.3	G234	M230-G234 PolarHBondContact O-N 3.12Å; M230-G234 VanDerWaalsContact O-N 3.11Å
231	P	83.5	Confident	85.6	Confident	70 Å²	70	43.2 Å²	43.2	46%	0.455	24%	0.237	S	C	.	.	H	α-helix	trans	-66.3	-42.4	177.1	-21	34.4	0	0	0	112.9	V227 I228 A233 G234 I235	V227-P231 WeakPolarHBondContact O-CD 3.4Å; I228-P231 WeakPolarHBondContact O-CD 3.42Å; P231-A233 PolarHBondContact O-N 3.1Å; P231-G234 PolarHBondContact O-N 3.39Å; P231-I235 WeakPolarHBondContact O-CG1 3.39Å; P231-I235 PolarHBondContact O-N 2.83Å
232	L	86.4	Confident	85.4	Confident	55 Å²	55	43.8 Å²	43.8	29%	0.288	24%	0.238	S	C	.	.	H	α-helix	trans	-64.3	-43.1	-178.7	-175.8	60.7	0	0	0	111.3	I228 I235 L236 Y249	I228-L232 WeakPolarHBondContact O-CB 3.5Å; I228-L232 PolarHBondContact O-N 3.46Å; L232-I235 PolarHBondContact O-N 3.33Å; L232-L236 HydrophobicContact CD1-CD1 4.33Å; L232-L236 HydrophobicContact CD1-CG 4.4Å; L232-L236 HydrophobicContact CG-CD1 4.04Å; L232-L236 WeakPolarHBondContact O-CB 3.31Å; L232-L236 VanDerWaalsContact O-CG 3.25Å; L232-L236 WeakPolarHBondContact O-CG 3.34Å; L232-L236 PolarHBondContact O-N 3.01Å; L232-Y249 HydrophobicContact CD2-CE2 4.32Å
233	A	83.8	Confident	85.5	Confident	0 Å²	0	45 Å²	45	0%	0	25%	0.246	C	C	.	.	H	α-helix	trans	-62	-42.9	174.8	0	0	0	0	0	111.5	V93 A229 P231 I235 L236 V237 V245	V93-A233 HydrophobicContact CB-CB 3.82Å; V93-A233 HydrophobicContact CG1-CB 3.87Å; V93-A233 HydrophobicContact CG2-CB 4.14Å; A229-A233 WeakPolarHBondContact O-CB 3.47Å; A229-A233 PolarHBondContact O-N 3.42Å; P231-A233 PolarHBondContact O-N 3.1Å; A233-I235 PolarHBondContact O-N 3.49Å; A233-L236 PolarHBondContact O-N 3.34Å; A233-V237 WeakPolarHBondContact O-CB 3.5Å; A233-V237 WeakPolarHBondContact O-CG2 3.02Å; A233-V237 PolarHBondContact O-N 3.32Å; A233-V245 HydrophobicContact CB-CG1 3.82Å; A233-V245 HydrophobicContact CB-CG2 4.38Å
234	G	80.8	Confident	85.6	Confident	29 Å²	29	44.6 Å²	44.6	30%	0.299	25%	0.246	S	C	.	.	H	α-helix	trans	-58.9	-46	177.9	0	0	0	0	0	113.1	M230 P231 Q238	M230-G234 PolarHBondContact O-N 3.12Å; M230-G234 VanDerWaalsContact O-N 3.11Å; P231-G234 PolarHBondContact O-N 3.39Å; G234-Q238 WeakPolarHBondContact O-CB 3.42Å; G234-Q238 PolarHBondContact O-N 3.12Å
235	I	85.1	Confident	85.7	Confident	93 Å²	93	43.5 Å²	43.5	48%	0.477	24%	0.238	S	C	.	.	H	α-helix	trans	-62.5	-49.5	176.5	-65.9	167.7	0	0	0	110.3	P231 L232 A233 V237 Q238 Y239	P231-I235 WeakPolarHBondContact O-CG1 3.39Å; P231-I235 PolarHBondContact O-N 2.83Å; L232-I235 PolarHBondContact O-N 3.33Å; A233-I235 PolarHBondContact O-N 3.49Å; I235-V237 PolarHBondContact O-N 3.32Å; I235-Q238 PolarHBondContact O-N 2.97Å; I235-Y239 HydrophobicContact CG2-CD2 3.76Å; I235-Y239 HydrophobicContact CG2-CE2 4.05Å; I235-Y239 VanDerWaalsContact O-CD2 3.28Å; I235-Y239 WeakPolarHBondContact O-CD2 3.41Å; I235-Y239 PolarHBondContact O-N 3.06Å
236	L	86.9	Confident	85.9	Confident	27 Å²	27	43.5 Å²	43.5	14%	0.141	24%	0.237	C	C	.	.	H	α-helix	trans	-60.5	-43.6	-178.8	-74.3	174.8	0	0	0	112.3	L232 A233 Q238 T240 G241 S244 V245 V248	L232-L236 HydrophobicContact CD1-CD1 4.33Å; L232-L236 HydrophobicContact CD1-CG 4.4Å; L232-L236 HydrophobicContact CG-CD1 4.04Å; L232-L236 WeakPolarHBondContact O-CB 3.31Å; L232-L236 VanDerWaalsContact O-CG 3.25Å; L232-L236 WeakPolarHBondContact O-CG 3.34Å; L232-L236 PolarHBondContact O-N 3.01Å; A233-L236 PolarHBondContact O-N 3.34Å; L236-Q238 PolarHBondContact O-N 3.4Å; L236-T240 PolarHBondContact O-N 3.23Å; L236-G241 PolarHBondContact O-N 3.46Å; L236-S244 PolarHBondContact O-OG 3.3Å; L236-V245 HydrophobicContact CB-CG2 3.92Å; L236-V248 HydrophobicContact CD1-CB 4.09Å; L236-V248 HydrophobicContact CD1-CG1 4.07Å; L236-V248 HydrophobicContact CD1-CG2 4.24Å; L236-V248 HydrophobicContact CD2-CG2 4.24Å
237	V	84	Confident	86.5	Confident	15 Å²	15	47.2 Å²	47.2	9%	0.091	25%	0.25	C	S	.	.	H	α-helix	trans	-59.5	-46.6	175.1	172.5	0	0	0	0	110.6	D97 A233 I235 G241 V245	D97-V237 HydrophobicContact CB-CG1 3.51Å; A233-V237 WeakPolarHBondContact O-CB 3.5Å; A233-V237 WeakPolarHBondContact O-CG2 3.02Å; A233-V237 PolarHBondContact O-N 3.32Å; I235-V237 PolarHBondContact O-N 3.32Å; V237-G241 WeakPolarHBondContact O-CA 3.48Å; V237-G241 PolarHBondContact O-N 2.89Å; V237-G241 VanDerWaalsContact O-N 3.08Å; V237-V245 HydrophobicContact CG2-CG2 3.59Å
238	Q	78.3	Confident	86.9	Confident	96 Å²	96	48.2 Å²	48.2	45%	0.449	26%	0.256	S	S	.	.	H	α-helix	trans	-67.1	-40.3	-175.6	-174.4	176.9	0.8	0	0	113.5	G234 I235 L236	G234-Q238 WeakPolarHBondContact O-CB 3.42Å; G234-Q238 PolarHBondContact O-N 3.12Å; I235-Q238 PolarHBondContact O-N 2.97Å; L236-Q238 PolarHBondContact O-N 3.4Å
239	Y	82.3	Confident	87	Confident	163 Å²	163	44.6 Å²	44.6	64%	0.639	24%	0.237	S	C	*	.	H	α-helix	trans	-93.3	-38.2	-174	-73.6	-79.9	0	0	0	113.8	I235	I235-Y239 HydrophobicContact CG2-CD2 3.76Å; I235-Y239 HydrophobicContact CG2-CE2 4.05Å; I235-Y239 VanDerWaalsContact O-CD2 3.28Å; I235-Y239 WeakPolarHBondContact O-CD2 3.41Å; I235-Y239 PolarHBondContact O-N 3.06Å
240	T	84.7	Confident	87.5	Confident	98 Å²	98	44.6 Å²	44.6	60%	0.601	24%	0.237	S	C	*	.	H	α-helix	trans	-118.8	-10.1	-169.8	-42.2	0	0	0	0	112.7	L236	L236-T240 PolarHBondContact O-N 3.23Å
241	G	84.6	Confident	88.3	Confident	17 Å²	17	43.6 Å²	43.6	18%	0.175	24%	0.237	C	C	.	.			trans	92.9	162	179.1	0	0	0	0	0	113.4	L236 V237 S243 S244	L236-G241 PolarHBondContact O-N 3.46Å; V237-G241 WeakPolarHBondContact O-CA 3.48Å; V237-G241 PolarHBondContact O-N 2.89Å; V237-G241 VanDerWaalsContact O-N 3.08Å; G241-S243 VanDerWaalsContact C-N 3.28Å; G241-S243 PolarHBondContact O-N 3.39Å; G241-S243 VanDerWaalsContact O-N 3.13Å; G241-S244 WeakPolarHBondContact O-CB 3.48Å; G241-S244 PolarHBondContact O-N 3.01Å; G241-S244 PolarHBondContact O-OG 2.88Å
242	W	88.6	Confident	88.8	Confident	17 Å²	17	45.7 Å²	45.7	6%	0.064	24%	0.239	C	C	.	.	H	α-helix	trans	-53.1	-35.8	-173.4	66.4	-89.8	0	0	0	115.4	D97 M98 K116 F117 P170 A173 S244 V245 F246	D97-W242 HydrophobicContact CB-CB 4.4Å; M98-W242 HydrophobicContact CE-CE3 4.14Å; M98-W242 HydrophobicContact CE-CH2 4.45Å; M98-W242 HydrophobicContact CE-CZ3 3.98Å; M98-W242 HydrophobicContact CG-CB 4.16Å; M98-W242 HydrophobicContact CG-CD2 3.89Å; M98-W242 HydrophobicContact CG-CE3 3.99Å; M98-W242 HydrophobicContact CG-CG 3.95Å; M98-W242 HydrophobicContact SD-CD2 4.31Å; M98-W242 HydrophobicContact SD-CE3 3.78Å; M98-W242 HydrophobicContact SD-CZ3 4.2Å; K116-W242 VanDerWaalsContact CD-CD1 3.45Å; F117-W242 HydrophobicContact CE2-CH2 4.15Å; F117-W242 AromaticContact CE2-CZ2 3.86Å; F117-W242 HydrophobicContact CE2-CZ2 3.86Å; F117-W242 HydrophobicContact CZ-CH2 4.12Å; F117-W242 AromaticContact CZ-CZ2 3.94Å; F117-W242 HydrophobicContact CZ-CZ2 3.94Å; P170-W242 HydrophobicContact CB-CH2 3.92Å; P170-W242 HydrophobicContact CB-CZ3 3.86Å; P170-W242 HydrophobicContact CG-CZ3 4.29Å; A173-W242 HydrophobicContact CB-CH2 4.05Å; A173-W242 HydrophobicContact CB-CZ3 4.25Å; W242-S244 PolarHBondContact O-N 3.18Å; W242-V245 PolarHBondContact O-N 3.35Å; W242-F246 HydrophobicContact CE3-CD2 4.3Å; W242-F246 AromaticContact CE3-CE2 3.89Å; W242-F246 HydrophobicContact CE3-CE2 3.89Å; W242-F246 HydrophobicContact CZ3-CE2 4.29Å; W242-F246 WeakPolarHBondContact O-CD2 3.38Å
243	S	92.4	Very high	89.2	Confident	27 Å²	27	43 Å²	43	19%	0.189	23%	0.225	C	C	.	.	H	α-helix	trans	-67.2	-25.1	-177.9	54.2	0	0	0	0	113	G241 V245 F246 Y247	G241-S243 VanDerWaalsContact C-N 3.28Å; G241-S243 PolarHBondContact O-N 3.39Å; G241-S243 VanDerWaalsContact O-N 3.13Å; S243-V245 VanDerWaalsContact C-N 3.3Å; S243-V245 PolarHBondContact O-N 2.94Å; S243-F246 PolarHBondContact O-N 3.21Å; S243-Y247 WeakPolarHBondContact O-CD2 3.31Å; S243-Y247 PolarHBondContact O-N 3.36Å
244	S	92.7	Very high	89.8	Confident	11 Å²	11	46.2 Å²	46.2	8%	0.077	24%	0.241	C	C	.	.	H	α-helix	trans	-62.3	-36.9	-177.6	66.6	0	0	0	0	112.6	L236 G241 W242 F246 Y247 V248	L236-S244 PolarHBondContact O-OG 3.3Å; G241-S244 WeakPolarHBondContact O-CB 3.48Å; G241-S244 PolarHBondContact O-N 3.01Å; G241-S244 PolarHBondContact O-OG 2.88Å; W242-S244 PolarHBondContact O-N 3.18Å; S244-F246 VanDerWaalsContact C-N 3.25Å; S244-F246 PolarHBondContact O-N 3.43Å; S244-Y247 PolarHBondContact O-N 3.1Å; S244-V248 WeakPolarHBondContact O-CB 3.5Å; S244-V248 VanDerWaalsContact O-CG2 3.31Å; S244-V248 WeakPolarHBondContact O-CG2 3.46Å; S244-V248 PolarHBondContact O-N 2.98Å
245	V	92	Very high	90.6	Very high	0 Å²	0	48.6 Å²	48.6	0%	0	25%	0.25	C	C	.	.	H	α-helix	trans	-57.9	-42.4	-179.3	-167.4	0	0	0	0	110.6	N90 A233 L236 V237 W242 S243 Y249	N90-V245 HydrophobicContact CB-CG1 3.67Å; A233-V245 HydrophobicContact CB-CG1 3.82Å; A233-V245 HydrophobicContact CB-CG2 4.38Å; L236-V245 HydrophobicContact CB-CG2 3.92Å; V237-V245 HydrophobicContact CG2-CG2 3.59Å; W242-V245 PolarHBondContact O-N 3.35Å; S243-V245 VanDerWaalsContact C-N 3.3Å; S243-V245 PolarHBondContact O-N 2.94Å; V245-Y249 HydrophobicContact CG1-CD2 3.89Å; V245-Y249 HydrophobicContact CG1-CE2 4.06Å; V245-Y249 VanDerWaalsContact O-CD2 3.32Å; V245-Y249 WeakPolarHBondContact O-CD2 3.41Å; V245-Y249 PolarHBondContact O-N 3.24Å; V245-Y249 VanDerWaalsContact O-N 3.17Å
246	F	95	Very high	91.1	Very high	0 Å²	0	44.8 Å²	44.8	0%	0	23%	0.229	C	C	.	.	H	α-helix	trans	-68.3	-43.1	-178.4	-60.9	-76.8	0	0	0	112.6	L91 A94 N166 I169 P170 W242 S243 S244 G250	L91-F246 HydrophobicContact CB-CE1 4.44Å; L91-F246 HydrophobicContact CD1-CE1 4.13Å; L91-F246 HydrophobicContact CD1-CZ 3.79Å; A94-F246 HydrophobicContact CB-CE2 3.72Å; A94-F246 HydrophobicContact CB-CZ 3.71Å; N166-F246 WeakPolarHBondContact ND2-CA 3.36Å; N166-F246 PolarHBondContact ND2-O 3.19Å; N166-F246 WeakPolarHBondContact O-CB 3.09Å; N166-F246 WeakPolarHBondContact OD1-CD1 3.4Å; I169-F246 HydrophobicContact CB-CD1 3.73Å; I169-F246 HydrophobicContact CB-CE1 3.95Å; I169-F246 HydrophobicContact CB-CG 4.19Å; I169-F246 HydrophobicContact CG1-CD1 4.17Å; I169-F246 HydrophobicContact CG1-CE1 4.32Å; I169-F246 HydrophobicContact CG2-CD1 3.77Å; I169-F246 HydrophobicContact CG2-CD2 4.46Å; I169-F246 HydrophobicContact CG2-CE1 3.48Å; I169-F246 VanDerWaalsContact CG2-CE1 3.48Å; I169-F246 HydrophobicContact CG2-CE2 4.2Å; I169-F246 HydrophobicContact CG2-CG 4.26Å; I169-F246 HydrophobicContact CG2-CZ 3.7Å; P170-F246 HydrophobicContact CG-CB 3.68Å; P170-F246 HydrophobicContact CG-CD2 3.82Å; P170-F246 HydrophobicContact CG-CG 3.94Å; W242-F246 HydrophobicContact CE3-CD2 4.3Å; W242-F246 AromaticContact CE3-CE2 3.89Å; W242-F246 HydrophobicContact CE3-CE2 3.89Å; W242-F246 HydrophobicContact CZ3-CE2 4.29Å; W242-F246 WeakPolarHBondContact O-CD2 3.38Å; S243-F246 PolarHBondContact O-N 3.21Å; S244-F246 VanDerWaalsContact C-N 3.25Å; S244-F246 PolarHBondContact O-N 3.43Å; F246-G250 PolarHBondContact O-N 3.33Å
247	Y	95.5	Very high	91.6	Very high	88 Å²	88	45.9 Å²	45.9	35%	0.345	23%	0.232	S	C	.	.	H	α-helix	trans	-70.5	-39	179.8	-63.2	-51.6	0	0	0	112.8	M167 P170 S243 S244 S251	M167-Y247 HydrophobicContact CB-CD1 4.26Å; M167-Y247 HydrophobicContact CE-CD1 4.32Å; M167-Y247 HydrophobicContact CG-CD1 4.41Å; M167-Y247 WeakPolarHBondContact O-CE1 3.33Å; P170-Y247 HydrophobicContact CB-CE2 4.43Å; P170-Y247 HydrophobicContact CG-CE1 4.33Å; P170-Y247 HydrophobicContact CG-CE2 4.18Å; S243-Y247 WeakPolarHBondContact O-CD2 3.31Å; S243-Y247 PolarHBondContact O-N 3.36Å; S244-Y247 PolarHBondContact O-N 3.1Å; Y247-S251 WeakPolarHBondContact O-CB 3.42Å; Y247-S251 PolarHBondContact O-N 2.92Å; Y247-S251 PolarHBondContact O-OG 3.46Å
248	V	94.4	Very high	92.1	Very high	45 Å²	45	50.9 Å²	50.9	27%	0.273	26%	0.255	S	S	.	.	H	α-helix	trans	-66	-50.6	178.9	170.8	0	0	0	0	110.8	L236 S244 G250 S251 F252	L236-V248 HydrophobicContact CD1-CB 4.09Å; L236-V248 HydrophobicContact CD1-CG1 4.07Å; L236-V248 HydrophobicContact CD1-CG2 4.24Å; L236-V248 HydrophobicContact CD2-CG2 4.24Å; S244-V248 WeakPolarHBondContact O-CB 3.5Å; S244-V248 VanDerWaalsContact O-CG2 3.31Å; S244-V248 WeakPolarHBondContact O-CG2 3.46Å; S244-V248 PolarHBondContact O-N 2.98Å; V248-G250 VanDerWaalsContact C-N 3.33Å; V248-G250 PolarHBondContact O-N 3.17Å; V248-S251 PolarHBondContact O-N 3.43Å; V248-F252 HydrophobicContact CG1-CD2 3.72Å; V248-F252 HydrophobicContact CG1-CE2 3.4Å; V248-F252 VanDerWaalsContact CG1-CE2 3.4Å; V248-F252 HydrophobicContact CG1-CZ 4.43Å; V248-F252 VanDerWaalsContact O-CD2 3.28Å; V248-F252 WeakPolarHBondContact O-CD2 3.29Å; V248-F252 PolarHBondContact O-N 3.21Å
249	Y	92.3	Very high	92.8	Very high	12 Å²	12	51.1 Å²	51.1	5%	0.047	26%	0.255	C	S	.	.	H	α-helix	trans	-63.8	-37.7	177.1	-87.8	-81.8	0	0	0	112.9	I87 N90 A229 L232 V245 F252 G253	I87-Y249 HydrophobicContact CG1-CD1 4.27Å; I87-Y249 HydrophobicContact CG1-CG 4.44Å; N90-Y249 HydrophobicContact CB-CD2 4.4Å; A229-Y249 WeakPolarHBondContact CA-OH 3.33Å; A229-Y249 WeakPolarHBondContact CB-OH 3.49Å; L232-Y249 HydrophobicContact CD2-CE2 4.32Å; V245-Y249 HydrophobicContact CG1-CD2 3.89Å; V245-Y249 HydrophobicContact CG1-CE2 4.06Å; V245-Y249 VanDerWaalsContact O-CD2 3.32Å; V245-Y249 WeakPolarHBondContact O-CD2 3.41Å; V245-Y249 PolarHBondContact O-N 3.24Å; V245-Y249 VanDerWaalsContact O-N 3.17Å; Y249-F252 PolarHBondContact O-N 2.92Å; Y249-G253 PolarHBondContact O-N 2.95Å; Y249-G253 VanDerWaalsContact O-N 3.12Å
250	G	94.6	Very high	93.4	Very high	0 Å²	0	43.6 Å²	43.6	0%	0	23%	0.226	C	C	.	.	H	α-helix	trans	-62	-44.6	174.2	0	0	0	0	0	112.4	S163 F246 V248 G253 M254	S163-G250 WeakPolarHBondContact O-CA 3.43Å; F246-G250 PolarHBondContact O-N 3.33Å; V248-G250 VanDerWaalsContact C-N 3.33Å; V248-G250 PolarHBondContact O-N 3.17Å; G250-G253 PolarHBondContact O-N 3.35Å; G250-M254 WeakPolarHBondContact O-CG 3.26Å; G250-M254 PolarHBondContact O-N 3Å; G250-M254 VanDerWaalsContact O-N 3.09Å
251	S	95.6	Very high	93.7	Very high	52 Å²	52	43.4 Å²	43.4	36%	0.364	22%	0.221	S	C	.	.	H	α-helix	trans	-63.6	-43.2	177.2	-56.9	0	0	0	0	112	Y247 V248 G253 M254 V255	Y247-S251 WeakPolarHBondContact O-CB 3.42Å; Y247-S251 PolarHBondContact O-N 2.92Å; Y247-S251 PolarHBondContact O-OG 3.46Å; V248-S251 PolarHBondContact O-N 3.43Å; S251-G253 VanDerWaalsContact C-N 3.33Å; S251-G253 PolarHBondContact O-N 3.33Å; S251-M254 PolarHBondContact O-N 3.39Å; S251-V255 WeakPolarHBondContact O-CG2 3.14Å; S251-V255 PolarHBondContact O-N 2.89Å
252	F	95	Very high	93.9	Very high	114 Å²	114	45.4 Å²	45.4	50%	0.5	23%	0.227	S	C	.	.	H	α-helix	trans	-59.8	-41.9	175.8	-80.4	-53.2	0	0	0	112.7	V248 Y249 V255 W256	V248-F252 HydrophobicContact CG1-CD2 3.72Å; V248-F252 HydrophobicContact CG1-CE2 3.4Å; V248-F252 VanDerWaalsContact CG1-CE2 3.4Å; V248-F252 HydrophobicContact CG1-CZ 4.43Å; V248-F252 VanDerWaalsContact O-CD2 3.28Å; V248-F252 WeakPolarHBondContact O-CD2 3.29Å; V248-F252 PolarHBondContact O-N 3.21Å; Y249-F252 PolarHBondContact O-N 2.92Å; F252-V255 PolarHBondContact O-N 3.45Å; F252-W256 VanDerWaalsContact O-CB 3.24Å; F252-W256 WeakPolarHBondContact O-CB 3.3Å; F252-W256 PolarHBondContact O-N 3.47Å
253	G	95.6	Very high	93.8	Very high	0 Å²	0	45.3 Å²	45.3	0%	0	23%	0.228	C	C	.	.	H	α-helix	trans	-67	-37.6	177.2	0	0	0	0	0	113.8	S163 Y249 G250 S251 W256 Y257	S163-G253 WeakPolarHBondContact OG-CA 3.25Å; Y249-G253 PolarHBondContact O-N 2.95Å; Y249-G253 VanDerWaalsContact O-N 3.12Å; G250-G253 PolarHBondContact O-N 3.35Å; S251-G253 VanDerWaalsContact C-N 3.33Å; S251-G253 PolarHBondContact O-N 3.33Å; G253-W256 PolarHBondContact O-N 3.36Å; G253-Y257 WeakPolarHBondContact O-CB 3.21Å; G253-Y257 PolarHBondContact O-N 3.26Å
254	M	95.6	Very high	93.7	Very high	67 Å²	67	44.6 Å²	44.6	33%	0.33	22%	0.223	S	C	.	.	H	α-helix	trans	-64.8	-45.8	173.9	-69.1	-171.2	-63.1	0	0	112	L160 T164 M167 G250 S251 Y257 M258	L160-M254 HydrophobicContact CD1-CG 4.04Å; T164-M254 HydrophobicContact CG2-SD 4.44Å; M167-M254 HydrophobicContact CE-CE 3.95Å; M167-M254 HydrophobicContact SD-CE 3.54Å; M167-M254 VanDerWaalsContact SD-CE 3.54Å; M167-M254 HydrophobicContact SD-SD 4.15Å; G250-M254 WeakPolarHBondContact O-CG 3.26Å; G250-M254 PolarHBondContact O-N 3Å; G250-M254 VanDerWaalsContact O-N 3.09Å; S251-M254 PolarHBondContact O-N 3.39Å; M254-Y257 PolarHBondContact O-N 2.85Å; M254-M258 PolarHBondContact O-N 3.18Å; M254-M258 VanDerWaalsContact O-N 3.17Å
255	V	96.5	Very high	93.5	Very high	79 Å²	79	46.7 Å²	46.7	48%	0.479	23%	0.23	S	C	.	.	H	α-helix	trans	-61.8	-45.6	176.4	171.6	0	0	0	0	110.4	S251 F252 Y257 M258 F259	S251-V255 WeakPolarHBondContact O-CG2 3.14Å; S251-V255 PolarHBondContact O-N 2.89Å; F252-V255 PolarHBondContact O-N 3.45Å; V255-Y257 VanDerWaalsContact C-N 3.28Å; V255-Y257 PolarHBondContact O-N 3.35Å; V255-M258 WeakPolarHBondContact O-CB 3.01Å; V255-M258 PolarHBondContact O-N 2.92Å; V255-F259 HydrophobicContact CG1-CD2 4.02Å; V255-F259 HydrophobicContact CG1-CE2 3.69Å; V255-F259 VanDerWaalsContact O-CD2 3.22Å; V255-F259 WeakPolarHBondContact O-CD2 3.5Å; V255-F259 PolarHBondContact O-N 3.23Å
256	W	97.1	Very high	93.2	Very high	13 Å²	13	48.4 Å²	48.4	5%	0.049	24%	0.238	C	C	.	.	H	α-helix	trans	-58.2	-40.5	175.7	174.7	91.9	0	0	0	112	M76 I83 F155 I159 F252 G253 M258 F259 W260	M76-W256 WeakPolarHBondContact O-CZ2 3.24Å; M76-W256 PolarHBondContact O-NE1 3.22Å; I83-W256 HydrophobicContact CD1-CB 3.52Å; I83-W256 HydrophobicContact CD1-CD2 4.47Å; I83-W256 HydrophobicContact CD1-CG 3.67Å; F155-W256 AromaticContact CD1-CH2 3.95Å; F155-W256 HydrophobicContact CD1-CH2 3.95Å; F155-W256 HydrophobicContact CD1-CZ2 4.48Å; F155-W256 AromaticContact CE1-CH2 3.74Å; F155-W256 HydrophobicContact CE1-CH2 3.74Å; F155-W256 AromaticContact CE1-CZ2 3.89Å; F155-W256 HydrophobicContact CE1-CZ2 3.89Å; I159-W256 HydrophobicContact CB-CE3 4.07Å; I159-W256 HydrophobicContact CB-CH2 4.32Å; I159-W256 HydrophobicContact CB-CZ3 3.61Å; I159-W256 HydrophobicContact CD1-CE3 4.21Å; I159-W256 HydrophobicContact CD1-CH2 3.24Å; I159-W256 HydrophobicContact CD1-CZ2 3.83Å; I159-W256 HydrophobicContact CD1-CZ3 3.45Å; I159-W256 VanDerWaalsContact CD1-CZ3 3.45Å; I159-W256 HydrophobicContact CG1-CH2 4.34Å; I159-W256 HydrophobicContact CG1-CZ3 4.12Å; I159-W256 HydrophobicContact CG2-CD2 4.37Å; I159-W256 HydrophobicContact CG2-CE3 3.53Å; I159-W256 HydrophobicContact CG2-CZ3 3.63Å; F252-W256 VanDerWaalsContact O-CB 3.24Å; F252-W256 WeakPolarHBondContact O-CB 3.3Å; F252-W256 PolarHBondContact O-N 3.47Å; G253-W256 PolarHBondContact O-N 3.36Å; W256-M258 VanDerWaalsContact C-N 3.32Å; W256-M258 PolarHBondContact O-N 3.1Å; W256-F259 PolarHBondContact O-N 3.01Å; W256-F259 VanDerWaalsContact O-N 3.16Å; W256-W260 HydrophobicContact CE3-CB 4.3Å; W256-W260 HydrophobicContact CH2-CB 3.9Å; W256-W260 AromaticContact CH2-CD2 3.57Å; W256-W260 HydrophobicContact CH2-CD2 3.57Å; W256-W260 AromaticContact CH2-CE3 3.75Å; W256-W260 HydrophobicContact CH2-CE3 3.75Å; W256-W260 AromaticContact CH2-CG 3.65Å; W256-W260 HydrophobicContact CH2-CG 3.65Å; W256-W260 HydrophobicContact CH2-CZ3 4.49Å; W256-W260 HydrophobicContact CZ2-CB 4.2Å; W256-W260 AromaticContact CZ2-CD2 3.81Å; W256-W260 HydrophobicContact CZ2-CD2 3.81Å; W256-W260 AromaticContact CZ2-CE3 3.47Å; W256-W260 HydrophobicContact CZ2-CE3 3.47Å; W256-W260 VanDerWaalsContact CZ2-CE3 3.47Å; W256-W260 HydrophobicContact CZ2-CG 4.15Å; W256-W260 HydrophobicContact CZ2-CZ3 4.11Å; W256-W260 HydrophobicContact CZ3-CB 3.96Å; W256-W260 HydrophobicContact CZ3-CD2 4.44Å; W256-W260 HydrophobicContact CZ3-CG 4.05Å; W256-W260 WeakPolarHBondContact O-CB 3.21Å; W256-W260 PolarHBondContact O-N 2.61Å
257	Y	96.6	Very high	92.7	Very high	49 Å²	49	49.6 Å²	49.6	19%	0.192	25%	0.246	C	C	.	.	H	α-helix	trans	-63.7	-36.7	178.2	-177.7	-105.1	0	0	0	112.4	G156 L160 G253 M254 V255 F259 W260 L261	G156-Y257 WeakPolarHBondContact O-CD2 3.48Å; G156-Y257 WeakPolarHBondContact O-CE2 3.4Å; L160-Y257 HydrophobicContact CB-CD1 4.32Å; L160-Y257 HydrophobicContact CB-CD2 3.94Å; L160-Y257 HydrophobicContact CB-CE2 4.3Å; L160-Y257 HydrophobicContact CB-CG 3.93Å; L160-Y257 HydrophobicContact CD1-CD1 3.99Å; L160-Y257 HydrophobicContact CD1-CG 4.12Å; L160-Y257 HydrophobicContact CD2-CD1 3.79Å; L160-Y257 HydrophobicContact CD2-CE1 3.63Å; L160-Y257 HydrophobicContact CD2-CE2 4.49Å; L160-Y257 HydrophobicContact CD2-CG 4.26Å; L160-Y257 HydrophobicContact CG-CD1 4.24Å; L160-Y257 HydrophobicContact CG-CG 4.32Å; G253-Y257 WeakPolarHBondContact O-CB 3.21Å; G253-Y257 PolarHBondContact O-N 3.26Å; M254-Y257 PolarHBondContact O-N 2.85Å; V255-Y257 VanDerWaalsContact C-N 3.28Å; V255-Y257 PolarHBondContact O-N 3.35Å; Y257-F259 VanDerWaalsContact C-N 3.34Å; Y257-F259 PolarHBondContact O-N 3.13Å; Y257-W260 WeakPolarHBondContact O-CB 3.48Å; Y257-W260 PolarHBondContact O-N 3.22Å; Y257-L261 HydrophobicContact CD1-CD1 3.99Å; Y257-L261 HydrophobicContact CD1-CG 4.26Å; Y257-L261 HydrophobicContact CE1-CD1 3.45Å; Y257-L261 VanDerWaalsContact CE1-CD1 3.45Å; Y257-L261 HydrophobicContact CE1-CD2 4.25Å; Y257-L261 HydrophobicContact CE1-CG 3.84Å; Y257-L261 HydrophobicContact CE2-CD2 4.32Å; Y257-L261 HydrophobicContact CE2-CG 4.35Å; Y257-L261 WeakPolarHBondContact O-CG 3.49Å; Y257-L261 PolarHBondContact O-N 3.15Å
258	M	94.5	Very high	92.2	Very high	120 Å²	120	45.7 Å²	45.7	59%	0.591	23%	0.232	S	C	*	.	H	α-helix	trans	-59.3	-45.5	172.9	-65.2	-60.3	-65.2	0	0	111.2	M254 V255 W256 L261 L262	M254-M258 PolarHBondContact O-N 3.18Å; M254-M258 VanDerWaalsContact O-N 3.17Å; V255-M258 WeakPolarHBondContact O-CB 3.01Å; V255-M258 PolarHBondContact O-N 2.92Å; W256-M258 VanDerWaalsContact C-N 3.32Å; W256-M258 PolarHBondContact O-N 3.1Å; M258-L261 PolarHBondContact O-N 3.4Å; M258-L262 WeakPolarHBondContact O-CG 3.38Å; M258-L262 PolarHBondContact O-N 3.02Å
259	F	93.3	Very high	91.6	Very high	102 Å²	102	45.3 Å²	45.3	45%	0.447	23%	0.233	S	C	.	.	H	α-helix	trans	-67.2	-36.2	174.9	-72.7	-75	0	0	0	112.7	M76 V255 W256 Y257 L261 L262 V263	M76-F259 HydrophobicContact CE-CB 3.76Å; V255-F259 HydrophobicContact CG1-CD2 4.02Å; V255-F259 HydrophobicContact CG1-CE2 3.69Å; V255-F259 VanDerWaalsContact O-CD2 3.22Å; V255-F259 WeakPolarHBondContact O-CD2 3.5Å; V255-F259 PolarHBondContact O-N 3.23Å; W256-F259 PolarHBondContact O-N 3.01Å; W256-F259 VanDerWaalsContact O-N 3.16Å; Y257-F259 VanDerWaalsContact C-N 3.34Å; Y257-F259 PolarHBondContact O-N 3.13Å; F259-L261 VanDerWaalsContact C-N 3.35Å; F259-L261 PolarHBondContact O-N 2.92Å; F259-L262 PolarHBondContact O-N 3.35Å; F259-V263 PolarHBondContact O-N 2.95Å
260	W	95	Very high	91.1	Very high	4 Å²	4	50.7 Å²	50.7	2%	0.015	26%	0.256	C	S	.	.	H	α-helix	trans	-60.8	-43.4	176.3	-177.1	-103	0	0	0	111.7	I73 M76 N152 F155 I201 W256 Y257 L262 V263 S264	I73-W260 HydrophobicContact CG2-CH2 4.45Å; M76-W260 HydrophobicContact CB-CE3 3.95Å; M76-W260 HydrophobicContact CB-CZ3 3.84Å; N152-W260 HydrophobicContact CB-CZ2 4.23Å; N152-W260 PolarHBondContact O-NE1 2.69Å; F155-W260 HydrophobicContact CB-CZ2 4.35Å; F155-W260 AromaticContact CD1-CE2 3.97Å; F155-W260 AromaticContact CD1-CH2 3.74Å; F155-W260 HydrophobicContact CD1-CH2 3.74Å; F155-W260 AromaticContact CD1-CZ2 3.52Å; F155-W260 HydrophobicContact CD1-CZ2 3.52Å; F155-W260 HydrophobicContact CD1-CZ3 4.35Å; F155-W260 HydrophobicContact CE1-CH2 4.04Å; F155-W260 HydrophobicContact CE1-CZ2 4.26Å; F155-W260 HydrophobicContact CE1-CZ3 4.31Å; F155-W260 HydrophobicContact CG-CZ2 4.32Å; I201-W260 HydrophobicContact CD1-CH2 3.99Å; I201-W260 HydrophobicContact CD1-CZ2 3.95Å; W256-W260 HydrophobicContact CE3-CB 4.3Å; W256-W260 HydrophobicContact CH2-CB 3.9Å; W256-W260 AromaticContact CH2-CD2 3.57Å; W256-W260 HydrophobicContact CH2-CD2 3.57Å; W256-W260 AromaticContact CH2-CE3 3.75Å; W256-W260 HydrophobicContact CH2-CE3 3.75Å; W256-W260 AromaticContact CH2-CG 3.65Å; W256-W260 HydrophobicContact CH2-CG 3.65Å; W256-W260 HydrophobicContact CH2-CZ3 4.49Å; W256-W260 HydrophobicContact CZ2-CB 4.2Å; W256-W260 AromaticContact CZ2-CD2 3.81Å; W256-W260 HydrophobicContact CZ2-CD2 3.81Å; W256-W260 AromaticContact CZ2-CE3 3.47Å; W256-W260 HydrophobicContact CZ2-CE3 3.47Å; W256-W260 VanDerWaalsContact CZ2-CE3 3.47Å; W256-W260 HydrophobicContact CZ2-CG 4.15Å; W256-W260 HydrophobicContact CZ2-CZ3 4.11Å; W256-W260 HydrophobicContact CZ3-CB 3.96Å; W256-W260 HydrophobicContact CZ3-CD2 4.44Å; W256-W260 HydrophobicContact CZ3-CG 4.05Å; W256-W260 WeakPolarHBondContact O-CB 3.21Å; W256-W260 PolarHBondContact O-N 2.61Å; Y257-W260 WeakPolarHBondContact O-CB 3.48Å; Y257-W260 PolarHBondContact O-N 3.22Å; W260-L262 VanDerWaalsContact C-N 3.28Å; W260-L262 PolarHBondContact O-N 3.5Å; W260-V263 PolarHBondContact O-N 3.07Å; W260-S264 VanDerWaalsContact CE2-CB 3.41Å; W260-S264 WeakPolarHBondContact CH2-OG 3.09Å; W260-S264 WeakPolarHBondContact CZ2-OG 3.23Å; W260-S264 WeakPolarHBondContact O-CA 3.29Å; W260-S264 WeakPolarHBondContact O-CB 3.44Å; W260-S264 PolarHBondContact O-N 3.14Å
261	L	91.3	Very high	90.6	Very high	95 Å²	95	50.9 Å²	50.9	50%	0.497	26%	0.257	S	S	.	.	H	α-helix	trans	-63	-32.8	176.7	-73.2	178.6	0	0	0	113.3	Y257 M258 F259	Y257-L261 HydrophobicContact CD1-CD1 3.99Å; Y257-L261 HydrophobicContact CD1-CG 4.26Å; Y257-L261 HydrophobicContact CE1-CD1 3.45Å; Y257-L261 VanDerWaalsContact CE1-CD1 3.45Å; Y257-L261 HydrophobicContact CE1-CD2 4.25Å; Y257-L261 HydrophobicContact CE1-CG 3.84Å; Y257-L261 HydrophobicContact CE2-CD2 4.32Å; Y257-L261 HydrophobicContact CE2-CG 4.35Å; Y257-L261 WeakPolarHBondContact O-CG 3.49Å; Y257-L261 PolarHBondContact O-N 3.15Å; M258-L261 PolarHBondContact O-N 3.4Å; F259-L261 VanDerWaalsContact C-N 3.35Å; F259-L261 PolarHBondContact O-N 2.92Å
262	L	88.1	Confident	89.9	Confident	58 Å²	58	49.7 Å²	49.7	30%	0.304	25%	0.248	S	C	.	.	H	α-helix	trans	-74.6	-33.8	-179.9	-66.2	172	0	0	0	112.5	L59 M258 F259 W260	L59-L262 HydrophobicContact CB-CD2 4.36Å; M258-L262 WeakPolarHBondContact O-CG 3.38Å; M258-L262 PolarHBondContact O-N 3.02Å; F259-L262 PolarHBondContact O-N 3.35Å; W260-L262 VanDerWaalsContact C-N 3.28Å; W260-L262 PolarHBondContact O-N 3.5Å
263	V	87.4	Confident	89.3	Confident	16 Å²	16	45.9 Å²	45.9	10%	0.097	23%	0.234	C	C	.	.	H	α-helix	trans	-108.4	-24.5	-167.9	178.9	0	0	0	0	113.3	C62 I72 F259 W260	C62-V263 HydrophobicContact CB-CG2 4.22Å; I72-V263 HydrophobicContact CG2-CG1 3.59Å; F259-V263 PolarHBondContact O-N 2.95Å; W260-V263 PolarHBondContact O-N 3.07Å
264	S	89.3	Confident	88.9	Confident	11 Å²	11	46.4 Å²	46.4	8%	0.077	24%	0.237	C	C	.	.			trans	-98.8	112.8	-168.7	-168	0	0	0	0	113.3	N152 W260	N152-S264 WeakPolarHBondContact CB-OG 3.21Å; N152-S264 PolarHBondContact ND2-O 3.41Å; W260-S264 VanDerWaalsContact CE2-CB 3.41Å; W260-S264 WeakPolarHBondContact CH2-OG 3.09Å; W260-S264 WeakPolarHBondContact CZ2-OG 3.23Å; W260-S264 WeakPolarHBondContact O-CA 3.29Å; W260-S264 WeakPolarHBondContact O-CB 3.44Å; W260-S264 PolarHBondContact O-N 3.14Å
265	Y	88.8	Confident	88.4	Confident	55 Å²	55	47 Å²	47	22%	0.216	25%	0.245	C	C	.	.			trans	-113.1	153.4	177.5	-64.7	-93.7	0	0	0	111.9	W205 S267 H271 P272	W205-Y265 PolarHBondContact NE1-O 3.44Å; Y265-S267 PolarHBondContact O-N 3.1Å; Y265-H271 HydrophobicContact CD2-CB 4.46Å; Y265-H271 AromaticContact CD2-CD2 3.27Å; Y265-H271 WeakPolarHBondContact CD2-CD2 3.19Å; Y265-H271 AromaticContact CD2-CG 3.88Å; Y265-H271 AromaticContact CD2-NE2 3.7Å; Y265-H271 HydrophobicContact CG-CB 4.36Å; Y265-H271 AromaticContact CG-CD2 3.93Å; Y265-P272 VanDerWaalsContact CE1-CD 3.48Å; Y265-P272 HydrophobicContact CE1-CG 4.04Å; Y265-P272 HydrophobicContact CE2-CG 4.27Å; Y265-P272 VanDerWaalsContact CZ-CD 3.41Å
266	E	85.8	Confident	87.8	Confident	37 Å²	37	48.6 Å²	48.6	17%	0.173	25%	0.251	C	S	.	.	S	Bend	trans	-68.9	-33.9	-170.5	-42.5	-176.9	160.5	0	0	113.1	A150 N152 R153 K270	A150-E266 HydrophobicContact CB-CB 4.38Å; A150-E266 VanDerWaalsContact CB-CD 3.43Å; A150-E266 HydrophobicContact CB-CG 3.85Å; A150-E266 VanDerWaalsContact CB-OE1 3.26Å; A150-E266 WeakPolarHBondContact CB-OE1 3.23Å; N152-E266 PolarHBondContact ND2-N 3.17Å; N152-E266 WeakPolarHBondContact OD1-CG 3.14Å; R153-E266 IonicContact CZ-OE1 3.09Å; R153-E266 IonicContact NE-OE1 3.82Å; R153-E266 PolarHBondContact NE-OE1 3.01Å; R153-E266 IonicContact NH2-OE1 2.72Å; R153-E266 PolarHBondContact NH2-OE1 3.47Å; E266-K270 IonicContact OE2-NZ 3.43Å; E266-K270 PolarHBondContact OE2-NZ 3.49Å
267	S	84.4	Confident	87.2	Confident	24 Å²	24	55.8 Å²	55.8	17%	0.168	29%	0.285	C	S	.	.	S	Bend	trans	-146.5	156	179.5	64	0	0	0	0	110.4	Y265 A269 K270 H271	Y265-S267 PolarHBondContact O-N 3.1Å; S267-A269 PolarHBondContact O-N 3.28Å; S267-K270 PolarHBondContact O-N 2.74Å; S267-K270 PolarHBondContact OG-N 3.46Å; S267-H271 PolarHBondContact O-N 3.45Å
268	P	84.9	Confident	86.8	Confident	7 Å²	7	54.1 Å²	54.1	5%	0.045	28%	0.279	C	S	.	.	G	3₁₀ helix	trans	-54.1	-40.6	173.2	-25.2	33.5	0	0	0	112.6	W205 K270 H271 I274 I282	W205-P268 HydrophobicContact CD2-CG 4.16Å; W205-P268 HydrophobicContact CE3-CG 4.21Å; W205-P268 HydrophobicContact CZ3-CG 4.45Å; P268-K270 VanDerWaalsContact C-N 3.32Å; P268-K270 PolarHBondContact O-N 2.86Å; P268-H271 WeakPolarHBondContact O-CB 3.39Å; P268-H271 PolarHBondContact O-N 3.3Å; P268-H271 VanDerWaalsContact O-N 3.09Å; P268-I274 HydrophobicContact CB-CD1 3.91Å; P268-I282 HydrophobicContact CB-CD1 4.45Å; P268-I282 HydrophobicContact CG-CB 4.38Å; P268-I282 HydrophobicContact CG-CD1 4.19Å; P268-I282 HydrophobicContact CG-CG2 3.77Å
269	A	81.8	Confident	86.4	Confident	36 Å²	36	52 Å²	52	30%	0.298	26%	0.264	S	S	.	.	G	3₁₀ helix	trans	-59	-38.5	179.3	0	0	0	0	0	113.8	K55 S267 H271	K55-A269 WeakPolarHBondContact CE-O 2.8Å; K55-A269 PolarHBondContact NZ-O 3.27Å; K55-A269 VanDerWaalsContact NZ-O 3.15Å; S267-A269 PolarHBondContact O-N 3.28Å; A269-H271 VanDerWaalsContact C-N 3.33Å
270	K	82.9	Confident	86.1	Confident	125 Å²	125	54.7 Å²	54.7	54%	0.543	27%	0.271	S	S	.	.	G	3₁₀ helix	trans	-81.7	-10.9	179.3	-68.3	-175.7	-175	-176.8	0	113.3	E266 S267 P268	E266-K270 IonicContact OE2-NZ 3.43Å; E266-K270 PolarHBondContact OE2-NZ 3.49Å; S267-K270 PolarHBondContact O-N 2.74Å; S267-K270 PolarHBondContact OG-N 3.46Å; P268-K270 VanDerWaalsContact C-N 3.32Å; P268-K270 PolarHBondContact O-N 2.86Å
271	H	83.6	Confident	85.8	Confident	4 Å²	4	58.9 Å²	58.9	2%	0.019	29%	0.288	C	S	.	.			trans	-71.4	126.4	-179.4	-167	-68.2	0	0	0	109.5	K55 W205 Y265 S267 P268 A269 T273 I274	K55-H271 PolarHBondContact NZ-O 2.89Å; W205-H271 HydrophobicContact CH2-CB 4.12Å; W205-H271 AromaticContact CH2-CD2 3.61Å; Y265-H271 HydrophobicContact CD2-CB 4.46Å; Y265-H271 AromaticContact CD2-CD2 3.27Å; Y265-H271 WeakPolarHBondContact CD2-CD2 3.19Å; Y265-H271 AromaticContact CD2-CG 3.88Å; Y265-H271 AromaticContact CD2-NE2 3.7Å; Y265-H271 HydrophobicContact CG-CB 4.36Å; Y265-H271 AromaticContact CG-CD2 3.93Å; S267-H271 PolarHBondContact O-N 3.45Å; P268-H271 WeakPolarHBondContact O-CB 3.39Å; P268-H271 PolarHBondContact O-N 3.3Å; P268-H271 VanDerWaalsContact O-N 3.09Å; A269-H271 VanDerWaalsContact C-N 3.33Å; H271-T273 PolarHBondContact CE1-OG1 2.79Å; H271-T273 PolarHBondContact ND1-N 3.09Å; H271-T273 VanDerWaalsContact ND1-N 3.19Å; H271-I274 HydrophobicContact CB-CB 4Å; H271-I274 HydrophobicContact CB-CG2 3.99Å; H271-I274 PolarHBondContact ND1-N 2.6Å
272	P	81.4	Confident	85.6	Confident	27 Å²	27	54.4 Å²	54.4	18%	0.175	27%	0.265	C	S	.	.	T	Hydrogen-bonded Turn	trans	-77	-32.6	-172.9	30.2	-35.3	0	0	0	113	K55 K56 P58 Y265	K55-P272 HydrophobicContact CB-CB 4.39Å; K56-P272 WeakPolarHBondContact O-CB 3.01Å; P58-P272 HydrophobicContact CB-CG 3.97Å; P58-P272 HydrophobicContact CG-CG 4.03Å; Y265-P272 VanDerWaalsContact CE1-CD 3.48Å; Y265-P272 HydrophobicContact CE1-CG 4.04Å; Y265-P272 HydrophobicContact CE2-CG 4.27Å; Y265-P272 VanDerWaalsContact CZ-CD 3.41Å
273	T	82.4	Confident	85.4	Confident	34 Å²	34	54.6 Å²	54.6	21%	0.209	26%	0.264	C	S	.	.	T	Hydrogen-bonded Turn	trans	-119.8	31.1	-173	58.1	0	0	0	0	113.7	P58 D61 R69 H271	P58-T273 HydrophobicContact CG-CG2 3.37Å; D61-T273 WeakPolarHBondContact OD1-CB 3.46Å; D61-T273 WeakPolarHBondContact OD1-CG2 3.42Å; D61-T273 PolarHBondContact OD1-OG1 2.91Å; D61-T273 VanDerWaalsContact OD2-CG2 3.22Å; D61-T273 WeakPolarHBondContact OD2-CG2 3.13Å; R69-T273 PolarHBondContact NE-O 2.88Å; R69-T273 VanDerWaalsContact NE-O 3.12Å; R69-T273 PolarHBondContact NH2-O 2.77Å; R69-T273 PolarHBondContact NH2-OG1 3.09Å; H271-T273 PolarHBondContact CE1-OG1 2.79Å; H271-T273 PolarHBondContact ND1-N 3.09Å; H271-T273 VanDerWaalsContact ND1-N 3.19Å
274	I	85.4	Confident	85.3	Confident	12 Å²	12	59.8 Å²	59.8	6%	0.062	29%	0.287	C	S	.	.			trans	-80.9	142.2	169.1	-167.1	168.5	0	0	0	107.8	R69 W205 P268 H271 E278 R279 I282	R69-I274 HydrophobicContact CG-CB 4.42Å; R69-I274 HydrophobicContact CG-CG1 4.23Å; W205-I274 HydrophobicContact CH2-CD1 4.41Å; W205-I274 HydrophobicContact CZ3-CD1 4.19Å; P268-I274 HydrophobicContact CB-CD1 3.91Å; H271-I274 HydrophobicContact CB-CB 4Å; H271-I274 HydrophobicContact CB-CG2 3.99Å; H271-I274 PolarHBondContact ND1-N 2.6Å; I274-E278 HydrophobicContact CD1-CB 4.5Å; I274-E278 HydrophobicContact CD1-CG 4.13Å; I274-E278 HydrophobicContact CG1-CB 4.13Å; I274-E278 HydrophobicContact CG1-CG 4.18Å; I274-R279 HydrophobicContact CD1-CB 4.27Å; I274-R279 HydrophobicContact CG1-CB 4.5Å; I274-R279 HydrophobicContact CG2-CB 4.22Å; I274-I282 HydrophobicContact CD1-CD1 4.46Å
275	T	86.2	Confident	85.1	Confident	80 Å²	80	61.1 Å²	61.1	49%	0.491	30%	0.296	S	S	.	.			trans	-71.2	143.5	173.5	56.1	0	0	0	0	109.6	E277 E278 R279	T275-E277 PolarHBondContact O-N 3.14Å; T275-E278 PolarHBondContact O-N 3.34Å; T275-E278 VanDerWaalsContact O-N 3.09Å; T275-E278 VanDerWaalsContact OG1-CB 3.27Å; T275-E278 WeakPolarHBondContact OG1-CB 3.45Å; T275-E278 PolarHBondContact OG1-N 3.43Å; T275-R279 PolarHBondContact O-N 2.8Å
276	D	83.4	Confident	84.6	Confident	111 Å²	111	59.5 Å²	59.5	59%	0.594	29%	0.291	S	S	*	.	H	α-helix	trans	-62.2	-32.6	-179.6	-64	-44.5	0	0	0	111.9	R279 R280	D276-R279 PolarHBondContact O-N 2.78Å; D276-R280 WeakPolarHBondContact O-CB 3.29Å; D276-R280 WeakPolarHBondContact O-CG 3.46Å; D276-R280 PolarHBondContact O-N 2.9Å
277	E	85.4	Confident	83.5	Confident	164 Å²	164	59.3 Å²	59.3	77%	0.766	30%	0.299	S	S	*	.	H	α-helix	trans	-59.6	-47.3	171.9	-64.3	178.4	-177.8	0	0	112.4	T275 Y281	T275-E277 PolarHBondContact O-N 3.14Å; E277-Y281 WeakPolarHBondContact O-CB 3.48Å; E277-Y281 PolarHBondContact O-N 3.11Å
278	E	87.3	Confident	81.8	Confident	14 Å²	14	65.9 Å²	65.9	7%	0.065	33%	0.327	C	S	.	.	H	α-helix	trans	-68.3	-41	179.2	179.6	170.7	-157.4	0	0	110.9	P68 R69 R70 I274 T275 Y281 I282	P68-E278 VanDerWaalsContact CB-OE1 3.31Å; P68-E278 WeakPolarHBondContact CB-OE1 3.16Å; R69-E278 PolarHBondContact N-OE1 3.47Å; R69-E278 PolarHBondContact N-OE2 3.06Å; R70-E278 WeakPolarHBondContact CG-OE1 3.4Å; R70-E278 IonicContact CZ-OE1 2.92Å; R70-E278 PolarHBondContact N-OE1 3.1Å; R70-E278 IonicContact NH1-OE1 3.86Å; R70-E278 PolarHBondContact NH1-OE1 3.4Å; I274-E278 HydrophobicContact CD1-CB 4.5Å; I274-E278 HydrophobicContact CD1-CG 4.13Å; I274-E278 HydrophobicContact CG1-CB 4.13Å; I274-E278 HydrophobicContact CG1-CG 4.18Å; T275-E278 PolarHBondContact O-N 3.34Å; T275-E278 VanDerWaalsContact O-N 3.09Å; T275-E278 VanDerWaalsContact OG1-CB 3.27Å; T275-E278 WeakPolarHBondContact OG1-CB 3.45Å; T275-E278 PolarHBondContact OG1-N 3.43Å; E278-Y281 PolarHBondContact O-N 3.13Å; E278-I282 HydrophobicContact CG-CD1 3.85Å; E278-I282 HydrophobicContact CG-CG1 4.49Å; E278-I282 VanDerWaalsContact O-CG1 3.29Å; E278-I282 WeakPolarHBondContact O-CG1 2.97Å; E278-I282 PolarHBondContact O-N 3.29Å
279	R	86.3	Confident	80	Confident	76 Å²	76	67.1 Å²	67.1	29%	0.287	34%	0.336	S	S	.	.	H	α-helix	trans	-59.4	-52.3	177.4	178.8	-176.8	170.1	-158.4	-6.7	111.1	I274 T275 D276 Y281 I282 E283	I274-R279 HydrophobicContact CD1-CB 4.27Å; I274-R279 HydrophobicContact CG1-CB 4.5Å; I274-R279 HydrophobicContact CG2-CB 4.22Å; T275-R279 PolarHBondContact O-N 2.8Å; D276-R279 PolarHBondContact O-N 2.78Å; R279-Y281 PolarHBondContact O-N 2.75Å; R279-I282 PolarHBondContact O-N 3.37Å; R279-E283 HydrophobicContact CG-CG 4.38Å; R279-E283 WeakPolarHBondContact CG-OE1 3.49Å; R279-E283 IonicContact CZ-OE1 3.75Å; R279-E283 IonicContact CZ-OE2 3.97Å; R279-E283 IonicContact NE-OE1 2.78Å; R279-E283 PolarHBondContact NE-OE1 3.07Å; R279-E283 IonicContact NE-OE2 2.73Å; R279-E283 PolarHBondContact NE-OE2 2.96Å; R279-E283 IonicContact NH2-OE1 3.69Å; R279-E283 IonicContact NH2-OE2 3.78Å; R279-E283 WeakPolarHBondContact O-CB 3.33Å; R279-E283 WeakPolarHBondContact O-CG 3.38Å; R279-E283 PolarHBondContact O-N 3.24Å
280	R	86.6	Confident	78.2	Confident	158 Å²	158	67.3 Å²	67.3	60%	0.596	34%	0.337	S	S	*	.	H	α-helix	trans	-60.5	-45	179	-74.8	-177.8	64.6	167	2.7	111.5	D276 I282 E283 E284	D276-R280 WeakPolarHBondContact O-CB 3.29Å; D276-R280 WeakPolarHBondContact O-CG 3.46Å; D276-R280 PolarHBondContact O-N 2.9Å; R280-I282 VanDerWaalsContact C-N 3.29Å; R280-I282 PolarHBondContact O-N 3.04Å; R280-E283 PolarHBondContact O-N 3.22Å; R280-E284 IonicContact CZ-OE1 2.77Å; R280-E284 IonicContact NE-OE1 3.47Å; R280-E284 PolarHBondContact NE-OE1 3.36Å; R280-E284 IonicContact NH2-OE1 3.87Å; R280-E284 PolarHBondContact NH2-OE1 3.48Å; R280-E284 WeakPolarHBondContact O-CB 3.48Å; R280-E284 VanDerWaalsContact O-CG 3.24Å; R280-E284 WeakPolarHBondContact O-CG 3.46Å; R280-E284 PolarHBondContact O-N 3.21Å
281	Y	88.7	Confident	76.3	Confident	92 Å²	92	68.3 Å²	68.3	36%	0.361	35%	0.349	S	S	.	.	H	α-helix	trans	-56	-42.9	176.1	175.6	-111.9	0	0	0	112.7	P207 E277 E278 R279 S285	P207-Y281 HydrophobicContact CB-CE1 4.18Å; P207-Y281 HydrophobicContact CG-CD1 4.21Å; P207-Y281 HydrophobicContact CG-CE1 3.7Å; E277-Y281 WeakPolarHBondContact O-CB 3.48Å; E277-Y281 PolarHBondContact O-N 3.11Å; E278-Y281 PolarHBondContact O-N 3.13Å; R279-Y281 PolarHBondContact O-N 2.75Å; Y281-S285 WeakPolarHBondContact O-CB 3.37Å; Y281-S285 PolarHBondContact O-N 3.31Å; Y281-S285 VanDerWaalsContact O-N 3.09Å; Y281-S285 PolarHBondContact O-OG 3.22Å
282	I	87.8	Confident	74.6	Confident	2 Å²	2	71.6 Å²	71.6	1%	0.01	37%	0.366	C	S	.	.	H	α-helix	trans	-70.8	-47.2	178.8	-63.7	166.5	0	0	0	111	W205 P207 P268 I274 E278 R279 R280 S285 I286	W205-I282 HydrophobicContact CE3-CD1 4.45Å; P207-I282 HydrophobicContact CG-CG1 4.15Å; P268-I282 HydrophobicContact CB-CD1 4.45Å; P268-I282 HydrophobicContact CG-CB 4.38Å; P268-I282 HydrophobicContact CG-CD1 4.19Å; P268-I282 HydrophobicContact CG-CG2 3.77Å; I274-I282 HydrophobicContact CD1-CD1 4.46Å; E278-I282 HydrophobicContact CG-CD1 3.85Å; E278-I282 HydrophobicContact CG-CG1 4.49Å; E278-I282 VanDerWaalsContact O-CG1 3.29Å; E278-I282 WeakPolarHBondContact O-CG1 2.97Å; E278-I282 PolarHBondContact O-N 3.29Å; R279-I282 PolarHBondContact O-N 3.37Å; R280-I282 VanDerWaalsContact C-N 3.29Å; R280-I282 PolarHBondContact O-N 3.04Å; I282-S285 PolarHBondContact O-N 3.4Å; I282-S285 PolarHBondContact O-OG 2.88Å; I282-S285 VanDerWaalsContact O-OG 3.09Å; I282-I286 HydrophobicContact CG2-CD1 3.61Å; I282-I286 HydrophobicContact CG2-CG1 4.4Å; I282-I286 WeakPolarHBondContact O-CB 3.07Å; I282-I286 VanDerWaalsContact O-CG1 3.3Å; I282-I286 WeakPolarHBondContact O-CG1 3.48Å; I282-I286 PolarHBondContact O-N 3.16Å
283	E	84.3	Confident	73	Confident	61 Å²	61	71.3 Å²	71.3	29%	0.285	36%	0.363	S	S	.	.	H	α-helix	trans	-65.1	-44.8	-177.8	-71.4	174.6	-178.5	0	0	111.5	R279 R280 I286 G287	R279-E283 HydrophobicContact CG-CG 4.38Å; R279-E283 WeakPolarHBondContact CG-OE1 3.49Å; R279-E283 IonicContact CZ-OE1 3.75Å; R279-E283 IonicContact CZ-OE2 3.97Å; R279-E283 IonicContact NE-OE1 2.78Å; R279-E283 PolarHBondContact NE-OE1 3.07Å; R279-E283 IonicContact NE-OE2 2.73Å; R279-E283 PolarHBondContact NE-OE2 2.96Å; R279-E283 IonicContact NH2-OE1 3.69Å; R279-E283 IonicContact NH2-OE2 3.78Å; R279-E283 WeakPolarHBondContact O-CB 3.33Å; R279-E283 WeakPolarHBondContact O-CG 3.38Å; R279-E283 PolarHBondContact O-N 3.24Å; R280-E283 PolarHBondContact O-N 3.22Å; E283-I286 PolarHBondContact O-N 3.49Å; E283-G287 PolarHBondContact O-N 3.39Å
284	E	85.4	Confident	71.1	Confident	126 Å²	126	72.9 Å²	72.9	59%	0.589	39%	0.386	S	S	*	.	H	α-helix	trans	-66.6	-37.9	177	-68	171.4	-171.6	0	0	111.7	R280	R280-E284 IonicContact CZ-OE1 2.77Å; R280-E284 IonicContact NE-OE1 3.47Å; R280-E284 PolarHBondContact NE-OE1 3.36Å; R280-E284 IonicContact NH2-OE1 3.87Å; R280-E284 PolarHBondContact NH2-OE1 3.48Å; R280-E284 WeakPolarHBondContact O-CB 3.48Å; R280-E284 VanDerWaalsContact O-CG 3.24Å; R280-E284 WeakPolarHBondContact O-CG 3.46Å; R280-E284 PolarHBondContact O-N 3.21Å
285	S	83.9	Confident	69.1	Low	39 Å²	39	75 Å²	75	27%	0.273	41%	0.405	S	S	.	.	H	α-helix	trans	-77.1	-23.7	-179.6	64.4	0	0	0	0	114.5	P207 P208 Y281 I282	P207-S285 WeakPolarHBondContact CB-OG 3.28Å; P208-S285 VanDerWaalsContact CD-O 3.27Å; P208-S285 WeakPolarHBondContact CD-O 3.48Å; P208-S285 WeakPolarHBondContact CG-O 3.4Å; Y281-S285 WeakPolarHBondContact O-CB 3.37Å; Y281-S285 PolarHBondContact O-N 3.31Å; Y281-S285 VanDerWaalsContact O-N 3.09Å; Y281-S285 PolarHBondContact O-OG 3.22Å; I282-S285 PolarHBondContact O-N 3.4Å; I282-S285 PolarHBondContact O-OG 2.88Å; I282-S285 VanDerWaalsContact O-OG 3.09Å
286	I	78	Confident	67.4	Low	21 Å²	21	72.4 Å²	72.4	11%	0.108	39%	0.387	C	S	.	.	H	α-helix	trans	-88.6	-27.1	174.2	-65.9	176.6	0	0	0	110.9	K204 I282 E283 A290	K204-I286 VanDerWaalsContact O-CD1 3.26Å; K204-I286 WeakPolarHBondContact O-CD1 3.32Å; I282-I286 HydrophobicContact CG2-CD1 3.61Å; I282-I286 HydrophobicContact CG2-CG1 4.4Å; I282-I286 WeakPolarHBondContact O-CB 3.07Å; I282-I286 VanDerWaalsContact O-CG1 3.3Å; I282-I286 WeakPolarHBondContact O-CG1 3.48Å; I282-I286 PolarHBondContact O-N 3.16Å; E283-I286 PolarHBondContact O-N 3.49Å; I286-A290 HydrophobicContact CG2-CB 4.3Å
287	G	62.8	Low	65.5	Low	33 Å²	33	76 Å²	76	34%	0.34	40%	0.401	S	S	.	.	T	Hydrogen-bonded Turn	trans	70.9	-175.8	-176.6	0	0	0	0	0	113.2	E283 S289 A290	E283-G287 PolarHBondContact O-N 3.39Å; G287-S289 PolarHBondContact O-N 3.37Å; G287-A290 PolarHBondContact O-N 3.32Å
288	E	49.4	Very low	63.7	Low	162 Å²	162	77.1 Å²	77.1	76%	0.757	40%	0.403	S	S	*	.	T	Hydrogen-bonded Turn	trans	-46.8	-13.6	179.4	-73.8	-178.1	141.3	0	0	115.6	A290 N291 L292	E288-A290 PolarHBondContact O-N 2.87Å; E288-N291 PolarHBondContact O-N 3.31Å; E288-L292 PolarHBondContact O-N 3.47Å
289	S	46.4	Very low	62.3	Low	32 Å²	32	81 Å²	81	22%	0.224	42%	0.42	C	S	.	.	H	α-helix	trans	-52	-31	168.2	-68.3	0	0	0	0	113.7	G287 L293	G287-S289 PolarHBondContact O-N 3.37Å; S289-L293 VanDerWaalsContact O-CD1 3.22Å; S289-L293 WeakPolarHBondContact O-CD1 3.43Å; S289-L293 WeakPolarHBondContact O-CG 3.48Å; S289-L293 PolarHBondContact O-N 2.99Å
290	A	44.8	Very low	61.5	Low	40 Å²	40	87.1 Å²	87.1	33%	0.331	45%	0.449	S	S	.	.	H	α-helix	trans	-71.6	-39.6	179.1	0	0	0	0	0	113.6	I286 G287 E288	I286-A290 HydrophobicContact CG2-CB 4.3Å; G287-A290 PolarHBondContact O-N 3.32Å; E288-A290 PolarHBondContact O-N 2.87Å
291	N	43.3	Very low	61.2	Low	146 Å²	146	80.1 Å²	80.1	78%	0.781	42%	0.423	S	S	*	.	H	α-helix	trans	-74.7	-29.6	178.1	-75.6	-25.7	0	0	0	112	E288	E288-N291 PolarHBondContact O-N 3.31Å
292	L	46.4	Very low	61.1	Low	74 Å²	74	77.3 Å²	77.3	39%	0.387	42%	0.416	S	S	.	.	H	α-helix	trans	-80.3	-16.4	176.9	-69.8	163.5	0	0	0	114.2	E288 G294 A295	E288-L292 PolarHBondContact O-N 3.47Å; L292-G294 VanDerWaalsContact C-N 3.3Å; L292-G294 PolarHBondContact O-N 3.08Å; L292-A295 PolarHBondContact O-N 3.28Å
293	L	49.4	Very low	61.1	Low	21 Å²	21	81.9 Å²	81.9	11%	0.11	43%	0.434	C	S	.	.	T	Hydrogen-bonded Turn	trans	-73.6	-19.6	176.7	-85.8	160.2	0	0	0	113.3	K204 S289 R440	K204-L293 HydrophobicContact CG-CD1 4.07Å; S289-L293 VanDerWaalsContact O-CD1 3.22Å; S289-L293 WeakPolarHBondContact O-CD1 3.43Å; S289-L293 WeakPolarHBondContact O-CG 3.48Å; S289-L293 PolarHBondContact O-N 2.99Å; L293-R440 HydrophobicContact CD2-CB 4.39Å; L293-R440 HydrophobicContact CD2-CG 4.16Å
294	G	42	Very low	61.3	Low	67 Å²	67	89.2 Å²	89.2	69%	0.691	46%	0.459	S	S	*	.	S	Bend	trans	-76.2	-26.6	172.3	0	0	0	0	0	113.2	L292 M296	L292-G294 VanDerWaalsContact C-N 3.3Å; L292-G294 PolarHBondContact O-N 3.08Å; G294-M296 PolarHBondContact O-N 3.35Å
295	A	43.8	Very low	61.4	Low	55 Å²	55	88.9 Å²	88.9	46%	0.455	46%	0.455	S	S	.	.			trans	-100.7	43	-176.1	0	0	0	0	0	112.6	L292 E297	L292-A295 PolarHBondContact O-N 3.28Å; A295-E297 PolarHBondContact O-N 2.91Å
296	M	48.9	Very low	61.6	Low	26 Å²	26	87 Å²	87	13%	0.128	44%	0.442	C	S	.	.	T	Hydrogen-bonded Turn	trans	-74.9	17.8	169.9	-134.1	-152.4	-57.4	0	0	113	S147 G294 K298	S147-M296 WeakPolarHBondContact O-CE 3.46Å; G294-M296 PolarHBondContact O-N 3.35Å; M296-K298 VanDerWaalsContact C-N 3.32Å; M296-K298 PolarHBondContact O-N 3.39Å
297	E	44.4	Very low	62.2	Low	187 Å²	187	90.6 Å²	90.6	87%	0.874	46%	0.457	S	S	*	.	T	Hydrogen-bonded Turn	trans	-77.8	-7.8	179.8	-78.2	-161.7	148.3	0	0	114.3	A295	A295-E297 PolarHBondContact O-N 2.91Å
298	K	47	Very low	63.5	Low	188 Å²	188	93.1 Å²	93.1	82%	0.817	47%	0.466	S	S	*	.	S	Bend	trans	-130.5	-3.8	-174.5	-74.6	-173	176.6	-177.8	0	118.1	M296	M296-K298 VanDerWaalsContact C-N 3.32Å; M296-K298 PolarHBondContact O-N 3.39Å
299	F	58.1	Low	65.5	Low	96 Å²	96	85.9 Å²	85.9	42%	0.421	43%	0.434	S	S	.	.	P	Polyproline II helix	trans	-103.9	122.2	-175.3	-62.2	-73.3	0	0	0	113.1	T301	F299-T301 PolarHBondContact O-N 2.94Å
300	K	70.3	Confident	67.8	Low	203 Å²	203	89.4 Å²	89.4	88%	0.883	45%	0.448	S	S	*	.	P	Polyproline II helix	trans	-66	120	173.9	-165.8	173.5	-175.9	175.2	0	108.8
301	T	80.8	Confident	70.2	Confident	11 Å²	11	88.2 Å²	88.2	7%	0.067	44%	0.436	C	S	.	.	P	Polyproline II helix	trans	-58.6	125	180	-52.8	0	0	0	0	110.3	F299 W303 F306 Y441 I444	F299-T301 PolarHBondContact O-N 2.94Å; T301-W303 VanDerWaalsContact C-N 3.25Å; T301-W303 HydrophobicContact CG2-CD2 4.36Å; T301-W303 HydrophobicContact CG2-CZ2 4.38Å; T301-W303 PolarHBondContact O-N 3.17Å; T301-F306 HydrophobicContact CG2-CE2 3.45Å; T301-F306 VanDerWaalsContact CG2-CE2 3.45Å; T301-F306 HydrophobicContact CG2-CZ 3.77Å; T301-Y441 HydrophobicContact CG2-CE1 4.44Å; T301-I444 HydrophobicContact CG2-CD1 4.04Å
302	P	85.4	Confident	72.6	Confident	33 Å²	33	81.8 Å²	81.8	21%	0.214	40%	0.403	C	S	.	.			trans	-82.3	65.5	-171.9	33.5	-36.5	0	0	0	112.1	R304 K305 F306 Y441	P302-R304 VanDerWaalsContact C-N 3.3Å; P302-R304 PolarHBondContact O-N 3.38Å; P302-K305 HydrophobicContact CB-CB 4.18Å; P302-K305 HydrophobicContact CB-CG 4.19Å; P302-K305 PolarHBondContact O-N 2.88Å; P302-F306 HydrophobicContact CG-CD1 4.39Å; P302-F306 HydrophobicContact CG-CE1 3.66Å; P302-F306 HydrophobicContact CG-CZ 3.94Å; P302-F306 PolarHBondContact O-N 3.31Å; P302-Y441 HydrophobicContact CG-CE2 4.29Å
303	W	88.1	Confident	74.9	Confident	99 Å²	99	82.6 Å²	82.6	38%	0.375	40%	0.401	S	S	.	.	H	α-helix	trans	-51.7	-45.1	-177.3	-65.2	99.8	0	0	0	113.3	Y144 T301 K305 F306 F307 I444 I448	Y144-W303 HydrophobicContact CD2-CZ2 4.14Å; Y144-W303 HydrophobicContact CE2-CZ2 4.25Å; T301-W303 VanDerWaalsContact C-N 3.25Å; T301-W303 HydrophobicContact CG2-CD2 4.36Å; T301-W303 HydrophobicContact CG2-CZ2 4.38Å; T301-W303 PolarHBondContact O-N 3.17Å; W303-K305 VanDerWaalsContact C-N 3.28Å; W303-K305 PolarHBondContact O-N 3.2Å; W303-F306 HydrophobicContact CE3-CD2 4.44Å; W303-F306 WeakPolarHBondContact O-CB 3.43Å; W303-F306 PolarHBondContact O-N 3.03Å; W303-F307 HydrophobicContact CE3-CE2 4.04Å; W303-F307 WeakPolarHBondContact O-CD2 3.36Å; W303-F307 PolarHBondContact O-N 3.07Å; W303-F307 VanDerWaalsContact O-N 3.14Å; W303-I444 HydrophobicContact CH2-CG2 4.22Å; W303-I444 HydrophobicContact CZ3-CG2 4.23Å; W303-I448 HydrophobicContact CZ3-CD1 4.28Å
304	R	88.2	Confident	77.1	Confident	215 Å²	215	81.6 Å²	81.6	81%	0.811	40%	0.396	S	S	*	.	H	α-helix	trans	-58.2	-41.8	179	-172.8	177.5	178.7	-173.4	0.5	111.3	P302 F307 T308	P302-R304 VanDerWaalsContact C-N 3.3Å; P302-R304 PolarHBondContact O-N 3.38Å; R304-F307 PolarHBondContact O-N 3.28Å; R304-T308 HydrophobicContact CG-CG2 4.48Å; R304-T308 VanDerWaalsContact O-CG2 3.27Å; R304-T308 WeakPolarHBondContact O-CG2 3.02Å; R304-T308 PolarHBondContact O-N 3.02Å; R304-T308 VanDerWaalsContact O-N 3.1Å; R304-T308 PolarHBondContact O-OG1 2.97Å
305	K	87.4	Confident	79.7	Confident	119 Å²	119	78.7 Å²	78.7	52%	0.517	36%	0.364	S	S	.	.	H	α-helix	trans	-69	-37.3	-179	-62.2	-69.9	-173.4	171.8	0	111.8	P302 W303 T308 S309 W505	P302-K305 HydrophobicContact CB-CB 4.18Å; P302-K305 HydrophobicContact CB-CG 4.19Å; P302-K305 PolarHBondContact O-N 2.88Å; W303-K305 VanDerWaalsContact C-N 3.28Å; W303-K305 PolarHBondContact O-N 3.2Å; K305-T308 WeakPolarHBondContact CA-OG1 3.49Å; K305-T308 PolarHBondContact O-N 3.36Å; K305-T308 PolarHBondContact O-OG1 3.33Å; K305-T308 VanDerWaalsContact O-OG1 3.09Å; K305-S309 WeakPolarHBondContact O-CB 3.35Å; K305-S309 PolarHBondContact O-N 2.97Å; K305-W505 HydrophobicContact CB-CB 3.96Å; K305-W505 HydrophobicContact CB-CG 3.91Å; K305-W505 HydrophobicContact CG-CB 4.25Å
306	F	88	Confident	82.1	Confident	0 Å²	0	77 Å²	77	0%	0	35%	0.347	C	S	.	.	H	α-helix	trans	-58.7	-48.8	173.8	-59.4	-16.5	0	0	0	111.2	T301 P302 W303 T308 S309 Y441 I444 L445 W505	T301-F306 HydrophobicContact CG2-CE2 3.45Å; T301-F306 VanDerWaalsContact CG2-CE2 3.45Å; T301-F306 HydrophobicContact CG2-CZ 3.77Å; P302-F306 HydrophobicContact CG-CD1 4.39Å; P302-F306 HydrophobicContact CG-CE1 3.66Å; P302-F306 HydrophobicContact CG-CZ 3.94Å; P302-F306 PolarHBondContact O-N 3.31Å; W303-F306 HydrophobicContact CE3-CD2 4.44Å; W303-F306 WeakPolarHBondContact O-CB 3.43Å; W303-F306 PolarHBondContact O-N 3.03Å; F306-T308 VanDerWaalsContact C-N 3.26Å; F306-T308 PolarHBondContact O-N 3.42Å; F306-S309 PolarHBondContact O-N 2.77Å; F306-Y441 AromaticContact CE1-CD2 3.9Å; F306-Y441 HydrophobicContact CE1-CD2 3.9Å; F306-Y441 HydrophobicContact CE1-CE2 4.4Å; F306-Y441 HydrophobicContact CE1-CG 4.06Å; F306-Y441 AromaticContact CZ-CD1 3.85Å; F306-Y441 HydrophobicContact CZ-CD1 3.85Å; F306-Y441 AromaticContact CZ-CD2 3.84Å; F306-Y441 HydrophobicContact CZ-CD2 3.84Å; F306-Y441 HydrophobicContact CZ-CE1 4.36Å; F306-Y441 HydrophobicContact CZ-CE2 4.34Å; F306-Y441 AromaticContact CZ-CG 3.56Å; F306-Y441 HydrophobicContact CZ-CG 3.56Å; F306-I444 HydrophobicContact CE2-CG2 4.37Å; F306-L445 HydrophobicContact CB-CD2 4.39Å; F306-L445 HydrophobicContact CD1-CD2 4.4Å; F306-L445 HydrophobicContact CD2-CD2 4.39Å; F306-L445 HydrophobicContact CG-CD2 4.17Å; F306-W505 HydrophobicContact CD1-CD2 4.24Å; F306-W505 AromaticContact CD1-CE3 3.71Å; F306-W505 HydrophobicContact CD1-CE3 3.71Å; F306-W505 AromaticContact CD1-CH2 3.89Å; F306-W505 HydrophobicContact CD1-CH2 3.89Å; F306-W505 HydrophobicContact CD1-CZ2 4.39Å; F306-W505 AromaticContact CD1-CZ3 3.51Å; F306-W505 HydrophobicContact CD1-CZ3 3.51Å; F306-W505 HydrophobicContact CE1-CD2 4.37Å; F306-W505 AromaticContact CE1-CE3 3.45Å; F306-W505 HydrophobicContact CE1-CE3 3.45Å; F306-W505 VanDerWaalsContact CE1-CE3 3.45Å; F306-W505 HydrophobicContact CE1-CH2 4.11Å; F306-W505 AromaticContact CE1-CZ3 3.29Å; F306-W505 HydrophobicContact CE1-CZ3 3.29Å; F306-W505 HydrophobicContact CZ-CZ3 4.44Å
307	F	90.3	Very high	84.3	Confident	95 Å²	95	77.8 Å²	77.8	42%	0.417	35%	0.354	S	S	.	.	T	Hydrogen-bonded Turn	trans	-80.2	1.1	-178.6	-67.7	-68.3	0	0	0	114.6	W303 R304 Y313 I448	W303-F307 HydrophobicContact CE3-CE2 4.04Å; W303-F307 WeakPolarHBondContact O-CD2 3.36Å; W303-F307 PolarHBondContact O-N 3.07Å; W303-F307 VanDerWaalsContact O-N 3.14Å; R304-F307 PolarHBondContact O-N 3.28Å; F307-Y313 WeakPolarHBondContact O-CE2 3.46Å; F307-Y313 VanDerWaalsContact O-CZ 3.28Å; F307-Y313 PolarHBondContact O-OH 3.13Å; F307-I448 HydrophobicContact CE1-CG2 4.35Å; F307-I448 HydrophobicContact CZ-CD1 4.13Å
308	T	90.3	Very high	86.7	Confident	87 Å²	87	68.9 Å²	68.9	53%	0.534	31%	0.312	S	S	.	.	T	Hydrogen-bonded Turn	trans	-108.8	-7.7	170.9	54.8	0	0	0	0	113.1	R304 K305 F306	R304-T308 HydrophobicContact CG-CG2 4.48Å; R304-T308 VanDerWaalsContact O-CG2 3.27Å; R304-T308 WeakPolarHBondContact O-CG2 3.02Å; R304-T308 PolarHBondContact O-N 3.02Å; R304-T308 VanDerWaalsContact O-N 3.1Å; R304-T308 PolarHBondContact O-OG1 2.97Å; K305-T308 WeakPolarHBondContact CA-OG1 3.49Å; K305-T308 PolarHBondContact O-N 3.36Å; K305-T308 PolarHBondContact O-OG1 3.33Å; K305-T308 VanDerWaalsContact O-OG1 3.09Å; F306-T308 VanDerWaalsContact C-N 3.26Å; F306-T308 PolarHBondContact O-N 3.42Å
309	S	92.8	Very high	88.9	Confident	10 Å²	10	60.4 Å²	60.4	7%	0.07	28%	0.276	C	S	.	.			trans	-85.1	120.3	-175.2	180	0	0	0	0	111.6	K305 F306 P311 V312 Y313	K305-S309 WeakPolarHBondContact O-CB 3.35Å; K305-S309 PolarHBondContact O-N 2.97Å; F306-S309 PolarHBondContact O-N 2.77Å; S309-P311 WeakPolarHBondContact OG-CD 3.22Å; S309-V312 WeakPolarHBondContact O-CB 3.21Å; S309-V312 PolarHBondContact O-N 3.25Å; S309-Y313 WeakPolarHBondContact O-CD2 2.93Å; S309-Y313 PolarHBondContact O-N 3.33Å
310	M	94.1	Very high	90.6	Very high	106 Å²	106	59.1 Å²	59.1	52%	0.522	27%	0.27	S	S	.	.	H	α-helix	trans	-61	-41.7	179.1	-66.2	-63.4	179.8	0	0	113.8	V312 Y313 A314 F497	M310-V312 VanDerWaalsContact C-N 3.25Å; M310-V312 PolarHBondContact O-N 3.28Å; M310-Y313 PolarHBondContact O-N 3.39Å; M310-A314 PolarHBondContact O-N 3.49Å; M310-F497 HydrophobicContact CB-CB 4.28Å; M310-F497 HydrophobicContact CB-CD1 4.22Å; M310-F497 HydrophobicContact CG-CD1 4.42Å
311	P	94.4	Very high	91.6	Very high	14 Å²	14	49.6 Å²	49.6	9%	0.091	23%	0.229	C	C	.	.	H	α-helix	trans	-57.7	-33.4	173.4	-29.9	36.7	0	0	0	114.5	S309 A314 I315 I437	S309-P311 WeakPolarHBondContact OG-CD 3.22Å; P311-A314 WeakPolarHBondContact O-CB 3.31Å; P311-A314 PolarHBondContact O-N 3.17Å; P311-I315 WeakPolarHBondContact O-CG1 3.32Å; P311-I315 PolarHBondContact O-N 2.94Å; P311-I437 HydrophobicContact CB-CD1 3.62Å
312	V	94.9	Very high	92.1	Very high	12 Å²	12	49.7 Å²	49.7	7%	0.073	23%	0.228	C	C	.	.	H	α-helix	trans	-67	-47	176.2	175.7	0	0	0	0	110.3	S309 M310 A314 I315 I316 L445 W505	S309-V312 WeakPolarHBondContact O-CB 3.21Å; S309-V312 PolarHBondContact O-N 3.25Å; M310-V312 VanDerWaalsContact C-N 3.25Å; M310-V312 PolarHBondContact O-N 3.28Å; V312-A314 VanDerWaalsContact C-N 3.3Å; V312-A314 PolarHBondContact O-N 3.35Å; V312-I315 PolarHBondContact O-N 3.43Å; V312-I316 HydrophobicContact CG1-CD1 3.94Å; V312-I316 WeakPolarHBondContact O-CG1 3.46Å; V312-I316 PolarHBondContact O-N 3.5Å; V312-L445 HydrophobicContact CG1-CD2 4.17Å; V312-L445 HydrophobicContact CG2-CD2 4.19Å; V312-W505 HydrophobicContact CG2-CH2 4.28Å; V312-W505 HydrophobicContact CG2-CZ2 3.95Å
313	Y	95.4	Very high	92.3	Very high	90 Å²	90	48.6 Å²	48.6	35%	0.353	22%	0.221	S	C	.	.	H	α-helix	trans	-61.4	-38.2	174.4	-75.8	-73	0	0	0	112.6	F307 S309 M310 I315 I316 V317	F307-Y313 WeakPolarHBondContact O-CE2 3.46Å; F307-Y313 VanDerWaalsContact O-CZ 3.28Å; F307-Y313 PolarHBondContact O-OH 3.13Å; S309-Y313 WeakPolarHBondContact O-CD2 2.93Å; S309-Y313 PolarHBondContact O-N 3.33Å; M310-Y313 PolarHBondContact O-N 3.39Å; Y313-I315 VanDerWaalsContact C-N 3.28Å; Y313-I315 PolarHBondContact O-N 2.76Å; Y313-I316 PolarHBondContact O-N 3.17Å; Y313-V317 WeakPolarHBondContact O-CB 3.33Å; Y313-V317 WeakPolarHBondContact O-CG2 3.31Å; Y313-V317 PolarHBondContact O-N 3.35Å
314	A	95.5	Very high	92.4	Very high	0 Å²	0	45 Å²	45	0%	0	21%	0.208	C	C	.	.	H	α-helix	trans	-57	-44.7	176.7	0	0	0	0	0	111.2	M310 P311 V312 A318 F493 Y494 F497 A498	M310-A314 PolarHBondContact O-N 3.49Å; P311-A314 WeakPolarHBondContact O-CB 3.31Å; P311-A314 PolarHBondContact O-N 3.17Å; V312-A314 VanDerWaalsContact C-N 3.3Å; V312-A314 PolarHBondContact O-N 3.35Å; A314-A318 WeakPolarHBondContact O-CB 3.28Å; A314-A318 PolarHBondContact O-N 3.45Å; A314-F493 HydrophobicContact CB-CD1 4.43Å; A314-F493 HydrophobicContact CB-CE1 4.35Å; A314-Y494 HydrophobicContact CB-CD2 4.04Å; A314-Y494 WeakPolarHBondContact O-CD2 3.43Å; A314-F497 HydrophobicContact CB-CB 4.16Å; A314-A498 HydrophobicContact CB-CB 4.28Å
315	I	94.9	Very high	92.4	Very high	6 Å²	6	34.8 Å²	34.8	3%	0.031	17%	0.169	C	C	.	.	H	α-helix	trans	-67	-43.1	176.7	-66.7	172.3	0	0	0	111.9	P311 V312 Y313 V317 A318 N319 N433 H434 I437 Y494	P311-I315 WeakPolarHBondContact O-CG1 3.32Å; P311-I315 PolarHBondContact O-N 2.94Å; V312-I315 PolarHBondContact O-N 3.43Å; Y313-I315 VanDerWaalsContact C-N 3.28Å; Y313-I315 PolarHBondContact O-N 2.76Å; I315-V317 PolarHBondContact O-N 2.96Å; I315-A318 PolarHBondContact O-N 3.46Å; I315-N319 WeakPolarHBondContact O-CB 3.3Å; I315-N319 PolarHBondContact O-N 3.39Å; I315-N433 HydrophobicContact CD1-CB 3.78Å; I315-N433 HydrophobicContact CG1-CB 4.26Å; I315-H434 WeakPolarHBondContact CG2-CE1 3.45Å; I315-H434 WeakPolarHBondContact CG2-NE2 3.48Å; I315-I437 HydrophobicContact CD1-CD1 3.42Å; I315-I437 VanDerWaalsContact CD1-CD1 3.42Å; I315-I437 HydrophobicContact CG1-CD1 4.44Å; I315-Y494 HydrophobicContact CG1-CE2 4.22Å
316	I	95.1	Very high	92.3	Very high	19 Å²	19	30.6 Å²	30.6	10%	0.097	15%	0.151	C	C	.	.	H	α-helix	trans	-59.5	-47.3	178.5	-68.7	169.3	0	0	0	110.5	V312 Y313 N319 F320 I448 V452	V312-I316 HydrophobicContact CG1-CD1 3.94Å; V312-I316 WeakPolarHBondContact O-CG1 3.46Å; V312-I316 PolarHBondContact O-N 3.5Å; Y313-I316 PolarHBondContact O-N 3.17Å; I316-N319 PolarHBondContact O-N 2.89Å; I316-F320 WeakPolarHBondContact O-CB 3.34Å; I316-F320 PolarHBondContact O-N 3.26Å; I316-I448 HydrophobicContact CD1-CG2 4.06Å; I316-V452 HydrophobicContact CG2-CB 3.93Å; I316-V452 HydrophobicContact CG2-CG1 3.71Å; I316-V452 HydrophobicContact CG2-CG2 4.13Å
317	V	94.9	Very high	92.1	Very high	44 Å²	44	31.7 Å²	31.7	27%	0.267	16%	0.156	S	C	.	.	H	α-helix	trans	-63.5	-45.4	177.8	171.7	0	0	0	0	110.8	Y313 I315 N319 F320 C321 F493	Y313-V317 WeakPolarHBondContact O-CB 3.33Å; Y313-V317 WeakPolarHBondContact O-CG2 3.31Å; Y313-V317 PolarHBondContact O-N 3.35Å; I315-V317 PolarHBondContact O-N 2.96Å; V317-N319 VanDerWaalsContact C-N 3.3Å; V317-N319 PolarHBondContact O-N 3.42Å; V317-F320 WeakPolarHBondContact O-CB 3.46Å; V317-F320 PolarHBondContact O-N 3.28Å; V317-C321 PolarHBondContact O-N 3.11Å; V317-C321 PolarHBondContact O-SG 3.36Å; V317-F493 HydrophobicContact CB-CD1 3.97Å; V317-F493 HydrophobicContact CB-CE1 4.38Å; V317-F493 HydrophobicContact CG1-CB 4.39Å; V317-F493 HydrophobicContact CG1-CD1 4.14Å; V317-F493 HydrophobicContact CG1-CG 4.46Å; V317-F493 HydrophobicContact CG2-CD1 3.97Å; V317-F493 HydrophobicContact CG2-CE1 3.97Å
318	A	94.4	Very high	91.9	Very high	0 Å²	0	27.3 Å²	27.3	0%	0	14%	0.137	C	C	.	.	H	α-helix	trans	-58.7	-42.8	176.5	0	0	0	0	0	111.8	A314 I315 C321 R322 F393 F430 Y494	A314-A318 WeakPolarHBondContact O-CB 3.28Å; A314-A318 PolarHBondContact O-N 3.45Å; I315-A318 PolarHBondContact O-N 3.46Å; A318-C321 PolarHBondContact O-N 2.94Å; A318-R322 WeakPolarHBondContact O-CB 3.26Å; A318-R322 PolarHBondContact O-N 3.05Å; A318-F393 HydrophobicContact CB-CE2 4.42Å; A318-F430 HydrophobicContact CB-CB 3.97Å; A318-F430 HydrophobicContact CB-CD2 4.44Å; A318-F430 HydrophobicContact CB-CG 4.09Å; A318-Y494 HydrophobicContact CB-CD2 3.72Å; A318-Y494 HydrophobicContact CB-CE2 4.17Å; A318-Y494 HydrophobicContact CB-CG 4.47Å
319	N	93.3	Very high	91.6	Very high	9 Å²	9	23.6 Å²	23.6	5%	0.048	11%	0.113	C	C	.	.	H	α-helix	trans	-70.9	-33.7	178.9	-162.8	36.2	0	0	0	112.9	I315 I316 V317 S323 F430 S449 N450	I315-N319 WeakPolarHBondContact O-CB 3.3Å; I315-N319 PolarHBondContact O-N 3.39Å; I316-N319 PolarHBondContact O-N 2.89Å; V317-N319 VanDerWaalsContact C-N 3.3Å; V317-N319 PolarHBondContact O-N 3.42Å; N319-S323 VanDerWaalsContact O-CB 3.27Å; N319-S323 WeakPolarHBondContact O-CB 3.4Å; N319-S323 PolarHBondContact O-N 3.11Å; N319-S323 PolarHBondContact O-OG 2.94Å; N319-F430 HydrophobicContact CB-CD2 4.29Å; N319-F430 HydrophobicContact CB-CE2 3.9Å; N319-F430 WeakPolarHBondContact OD1-CE2 3.48Å; N319-S449 VanDerWaalsContact CB-OG 3.31Å; N319-S449 WeakPolarHBondContact CB-OG 3.42Å; N319-S449 PolarHBondContact ND2-O 3.47Å; N319-S449 PolarHBondContact ND2-OG 3.04Å; N319-N450 WeakPolarHBondContact ND2-CA 3.35Å; N319-N450 PolarHBondContact ND2-N 3.02Å
320	F	93.5	Very high	90.8	Very high	69 Å²	69	26.2 Å²	26.2	30%	0.303	13%	0.126	S	C	.	.	H	α-helix	trans	-61.2	-50	171.8	177.3	-87.9	0	0	0	111.6	I316 V317 S323 W324 V452 S456	I316-F320 WeakPolarHBondContact O-CB 3.34Å; I316-F320 PolarHBondContact O-N 3.26Å; V317-F320 WeakPolarHBondContact O-CB 3.46Å; V317-F320 PolarHBondContact O-N 3.28Å; F320-S323 PolarHBondContact O-N 3.35Å; F320-W324 HydrophobicContact CE1-CE3 4.06Å; F320-W324 AromaticContact CZ-CE3 3.9Å; F320-W324 HydrophobicContact CZ-CE3 3.9Å; F320-W324 HydrophobicContact CZ-CZ3 4.15Å; F320-W324 PolarHBondContact O-N 2.7Å; F320-V452 HydrophobicContact CD2-CG1 4.35Å; F320-S456 VanDerWaalsContact CE2-CB 3.49Å; F320-S456 PolarHBondContact O-OG 3.05Å
321	C	92.8	Very high	89.9	Confident	4 Å²	4	24.8 Å²	24.8	3%	0.027	12%	0.12	C	C	.	.	H	α-helix	trans	-61.3	-45.7	177.2	-63.5	0	0	0	0	110.9	V317 A318 S323 W324 T325 V486 H487	V317-C321 PolarHBondContact O-N 3.11Å; V317-C321 PolarHBondContact O-SG 3.36Å; A318-C321 PolarHBondContact O-N 2.94Å; C321-S323 VanDerWaalsContact C-N 3.35Å; C321-S323 PolarHBondContact O-N 3.2Å; C321-W324 WeakPolarHBondContact O-CB 3.14Å; C321-W324 PolarHBondContact O-N 3.09Å; C321-T325 PolarHBondContact O-N 2.64Å; C321-V486 HydrophobicContact CB-CG1 4.25Å; C321-V486 PolarHBondContact SG-O 3.17Å; C321-H487 PolarHBondContact O-CE1 2.88Å; C321-H487 PolarHBondContact O-NE2 3.45Å
322	R	90.9	Very high	89.1	Confident	12 Å²	12	24.6 Å²	24.6	5%	0.045	12%	0.119	C	C	.	.	H	α-helix	trans	-56.1	-49.9	176.5	179	57	-170.5	108.3	10.6	112.3	Y223 A318 W324 T325 F326 F393 F430	Y223-R322 PolarHBondContact OH-NH2 3.02Å; A318-R322 WeakPolarHBondContact O-CB 3.26Å; A318-R322 PolarHBondContact O-N 3.05Å; R322-W324 VanDerWaalsContact C-N 3.29Å; R322-W324 PolarHBondContact O-N 2.91Å; R322-T325 PolarHBondContact O-N 3.49Å; R322-F326 WeakPolarHBondContact O-CB 3.33Å; R322-F326 PolarHBondContact O-N 3.3Å; R322-F393 HydrophobicContact CB-CE1 4.33Å; R322-F393 HydrophobicContact CB-CE2 4.22Å; R322-F393 HydrophobicContact CB-CZ 3.57Å; R322-F393 HydrophobicContact CG-CE1 4.43Å; R322-F393 HydrophobicContact CG-CZ 4.01Å; R322-F430 HydrophobicContact CB-CE1 4.26Å; R322-F430 HydrophobicContact CB-CZ 4.07Å; R322-F430 HydrophobicContact CG-CE1 4.1Å; R322-F430 HydrophobicContact CG-CZ 3.88Å
323	S	89.8	Confident	88.5	Confident	10 Å²	10	24.4 Å²	24.4	7%	0.07	12%	0.117	C	C	.	.	H	α-helix	trans	-63.4	-40.9	-177.6	-62.1	0	0	0	0	110.3	N319 F320 C321 T325 F326 Y327 G453	N319-S323 VanDerWaalsContact O-CB 3.27Å; N319-S323 WeakPolarHBondContact O-CB 3.4Å; N319-S323 PolarHBondContact O-N 3.11Å; N319-S323 PolarHBondContact O-OG 2.94Å; F320-S323 PolarHBondContact O-N 3.35Å; C321-S323 VanDerWaalsContact C-N 3.35Å; C321-S323 PolarHBondContact O-N 3.2Å; S323-T325 PolarHBondContact O-N 3.08Å; S323-F326 PolarHBondContact O-N 2.97Å; S323-Y327 WeakPolarHBondContact O-CD2 3.46Å; S323-Y327 PolarHBondContact O-N 3.45Å; S323-G453 WeakPolarHBondContact CB-O 3.34Å; S323-G453 WeakPolarHBondContact OG-CA 3.35Å; S323-G453 PolarHBondContact OG-O 3.17Å
324	W	89.8	Confident	87.7	Confident	24 Å²	24	22.4 Å²	22.4	9%	0.091	12%	0.115	C	C	.	.	H	α-helix	trans	-51.9	-55.4	175.1	-171	-75.8	0	0	0	111.7	F320 C321 R322 L328 S456 C460 I463 I482	F320-W324 HydrophobicContact CE1-CE3 4.06Å; F320-W324 AromaticContact CZ-CE3 3.9Å; F320-W324 HydrophobicContact CZ-CE3 3.9Å; F320-W324 HydrophobicContact CZ-CZ3 4.15Å; F320-W324 PolarHBondContact O-N 2.7Å; C321-W324 WeakPolarHBondContact O-CB 3.14Å; C321-W324 PolarHBondContact O-N 3.09Å; R322-W324 VanDerWaalsContact C-N 3.29Å; R322-W324 PolarHBondContact O-N 2.91Å; W324-L328 VanDerWaalsContact O-CB 3.28Å; W324-L328 WeakPolarHBondContact O-CB 3.45Å; W324-L328 PolarHBondContact O-N 3.02Å; W324-S456 WeakPolarHBondContact CB-OG 3.28Å; W324-S456 PolarHBondContact N-OG 3.3Å; W324-C460 HydrophobicContact CD2-CB 4.31Å; W324-I463 HydrophobicContact CH2-CD1 3.61Å; W324-I463 HydrophobicContact CZ2-CD1 4.46Å; W324-I463 HydrophobicContact CZ3-CD1 4.35Å; W324-I482 HydrophobicContact CZ2-CG2 4.45Å
325	T	88.4	Confident	87	Confident	0 Å²	0	23.9 Å²	23.9	0%	0	13%	0.128	C	C	.	.	H	α-helix	trans	-71.1	-34.3	-179.8	-76.9	0	0	0	0	112.9	C321 R322 S323 Y327 L328 L329 E396 L400 H487	C321-T325 PolarHBondContact O-N 2.64Å; R322-T325 PolarHBondContact O-N 3.49Å; S323-T325 PolarHBondContact O-N 3.08Å; T325-Y327 PolarHBondContact O-N 3.23Å; T325-L328 PolarHBondContact O-N 3.32Å; T325-L329 HydrophobicContact CG2-CD1 3.75Å; T325-L329 HydrophobicContact CG2-CG 4.06Å; T325-L329 WeakPolarHBondContact O-CB 3.4Å; T325-L329 WeakPolarHBondContact O-CG 3.31Å; T325-L329 PolarHBondContact O-N 3.31Å; T325-E396 WeakPolarHBondContact CG2-OE1 3.36Å; T325-L400 HydrophobicContact CG2-CD1 3.82Å; T325-H487 WeakPolarHBondContact CB-CE1 3.46Å; T325-H487 WeakPolarHBondContact CB-NE2 3.33Å; T325-H487 PolarHBondContact OG1-CE1 3.03Å; T325-H487 PolarHBondContact OG1-ND1 3.36Å; T325-H487 PolarHBondContact OG1-NE2 3.01Å
326	F	85.9	Confident	86.6	Confident	32 Å²	32	23.7 Å²	23.7	14%	0.14	13%	0.127	C	C	.	.	H	α-helix	trans	-56.8	-50.2	175.4	-176.6	-117.7	0	0	0	111.7	Y223 R322 S323 L330	Y223-F326 HydrophobicContact CD1-CE2 4.28Å; Y223-F326 HydrophobicContact CE1-CD2 4.44Å; Y223-F326 AromaticContact CE1-CE2 3.85Å; Y223-F326 HydrophobicContact CE1-CE2 3.85Å; Y223-F326 HydrophobicContact CE1-CZ 4.43Å; R322-F326 WeakPolarHBondContact O-CB 3.33Å; R322-F326 PolarHBondContact O-N 3.3Å; S323-F326 PolarHBondContact O-N 2.97Å; F326-L330 HydrophobicContact CE1-CD1 4.06Å; F326-L330 HydrophobicContact CE2-CD1 4.46Å; F326-L330 HydrophobicContact CZ-CD1 3.84Å; F326-L330 VanDerWaalsContact O-CB 3.24Å; F326-L330 WeakPolarHBondContact O-CB 3.29Å; F326-L330 PolarHBondContact O-N 3.49Å
327	Y	83.1	Confident	86.1	Confident	23 Å²	23	23 Å²	23	9%	0.09	12%	0.123	C	C	.	.	H	α-helix	trans	-73.8	-35.5	-179.6	-68.7	-66.9	0	0	0	112.5	F132 S323 T325 L329 L330 I331 G457	F132-Y327 AromaticContact CE1-CE1 3.79Å; F132-Y327 HydrophobicContact CE1-CE1 3.79Å; F132-Y327 AromaticContact CE1-CZ 3.98Å; F132-Y327 AromaticContact CZ-CE1 3.87Å; F132-Y327 HydrophobicContact CZ-CE1 3.87Å; S323-Y327 WeakPolarHBondContact O-CD2 3.46Å; S323-Y327 PolarHBondContact O-N 3.45Å; T325-Y327 PolarHBondContact O-N 3.23Å; Y327-L329 VanDerWaalsContact C-N 3.34Å; Y327-L329 PolarHBondContact O-N 2.95Å; Y327-L330 PolarHBondContact O-N 3.46Å; Y327-I331 WeakPolarHBondContact O-CB 3.32Å; Y327-I331 WeakPolarHBondContact O-CG1 3.33Å; Y327-I331 PolarHBondContact O-N 2.95Å; Y327-G457 VanDerWaalsContact CE2-CA 3.49Å
328	L	86.3	Confident	85.4	Confident	3 Å²	3	25.3 Å²	25.3	2%	0.016	13%	0.131	C	C	.	.	H	α-helix	trans	-55	-50.7	171.7	176.8	65.9	0	0	0	110.9	W324 T325 S332 V464 V479 A483	W324-L328 VanDerWaalsContact O-CB 3.28Å; W324-L328 WeakPolarHBondContact O-CB 3.45Å; W324-L328 PolarHBondContact O-N 3.02Å; T325-L328 PolarHBondContact O-N 3.32Å; L328-S332 WeakPolarHBondContact O-CA 3.38Å; L328-S332 WeakPolarHBondContact O-CB 3.44Å; L328-S332 PolarHBondContact O-N 3.34Å; L328-S332 PolarHBondContact O-OG 3.48Å; L328-V464 HydrophobicContact CD1-CG2 3.64Å; L328-V479 HydrophobicContact CD1-CG1 3.77Å; L328-A483 HydrophobicContact CD2-CB 3.59Å
329	L	83.7	Confident	85	Confident	9 Å²	9	28 Å²	28	5%	0.047	14%	0.143	C	C	.	.	H	α-helix	trans	-71.7	-37	-180	-64.8	179.4	0	0	0	111.8	T325 Y327 I331 Q333 L400 L416 V420	T325-L329 HydrophobicContact CG2-CD1 3.75Å; T325-L329 HydrophobicContact CG2-CG 4.06Å; T325-L329 WeakPolarHBondContact O-CB 3.4Å; T325-L329 WeakPolarHBondContact O-CG 3.31Å; T325-L329 PolarHBondContact O-N 3.31Å; Y327-L329 VanDerWaalsContact C-N 3.34Å; Y327-L329 PolarHBondContact O-N 2.95Å; L329-I331 PolarHBondContact O-N 3.18Å; L329-Q333 WeakPolarHBondContact O-CB 3.33Å; L329-Q333 PolarHBondContact O-N 2.89Å; L329-L400 HydrophobicContact CD2-CD2 4.16Å; L329-L416 HydrophobicContact CD2-CD1 4.23Å; L329-V420 HydrophobicContact CD1-CG2 3.42Å; L329-V420 VanDerWaalsContact CD1-CG2 3.42Å
330	L	76.1	Confident	84.7	Confident	65 Å²	65	29.1 Å²	29.1	34%	0.34	15%	0.15	S	C	.	.	H	α-helix	trans	-65.9	-38.5	179.9	-172.1	146.3	0	0	0	112.7	F326 Y327	F326-L330 HydrophobicContact CE1-CD1 4.06Å; F326-L330 HydrophobicContact CE2-CD1 4.46Å; F326-L330 HydrophobicContact CZ-CD1 3.84Å; F326-L330 VanDerWaalsContact O-CB 3.24Å; F326-L330 WeakPolarHBondContact O-CB 3.29Å; F326-L330 PolarHBondContact O-N 3.49Å; Y327-L330 PolarHBondContact O-N 3.46Å
331	I	74.6	Confident	84.2	Confident	75 Å²	75	26.6 Å²	26.6	39%	0.385	14%	0.139	S	C	.	.	H	α-helix	trans	-98.4	-44.7	-171.9	-62.9	168.3	0	0	0	111.5	Y327 L329 P461	Y327-I331 WeakPolarHBondContact O-CB 3.32Å; Y327-I331 WeakPolarHBondContact O-CG1 3.33Å; Y327-I331 PolarHBondContact O-N 2.95Å; L329-I331 PolarHBondContact O-N 3.18Å; I331-P461 HydrophobicContact CD1-CB 4.34Å; I331-P461 HydrophobicContact CD1-CG 3.42Å; I331-P461 VanDerWaalsContact CD1-CG 3.42Å
332	S	77.8	Confident	83.5	Confident	10 Å²	10	29.2 Å²	29.2	7%	0.07	17%	0.167	C	C	.	.	H	α-helix	trans	-94.3	-12.4	-169.4	-51.9	0	0	0	0	113.3	L328 A335 Y336	L328-S332 WeakPolarHBondContact O-CA 3.38Å; L328-S332 WeakPolarHBondContact O-CB 3.44Å; L328-S332 PolarHBondContact O-N 3.34Å; L328-S332 PolarHBondContact O-OG 3.48Å; S332-A335 PolarHBondContact O-N 3.37Å; S332-Y336 WeakPolarHBondContact O-CB 3.21Å; S332-Y336 PolarHBondContact O-N 2.74Å
333	Q	82.6	Confident	82.7	Confident	8 Å²	8	31 Å²	31	4%	0.037	18%	0.175	C	C	.	.	H	α-helix	trans	-58.9	-47.8	177.4	176.3	-179.1	-22.2	0	0	112.6	L329 A335 Y336 F337 L416	L329-Q333 WeakPolarHBondContact O-CB 3.33Å; L329-Q333 PolarHBondContact O-N 2.89Å; Q333-A335 PolarHBondContact O-N 3.12Å; Q333-Y336 PolarHBondContact O-N 2.79Å; Q333-F337 HydrophobicContact CG-CD2 3.83Å; Q333-F337 HydrophobicContact CG-CE2 3.7Å; Q333-F337 VanDerWaalsContact O-CD2 3.23Å; Q333-F337 WeakPolarHBondContact O-CD2 3.25Å; Q333-F337 PolarHBondContact O-N 3.23Å; Q333-L416 HydrophobicContact CG-CD1 4.23Å
334	P	78.5	Confident	81.7	Confident	48 Å²	48	36 Å²	36	31%	0.312	20%	0.197	S	C	.	.	H	α-helix	trans	-62.1	-44.6	178	-23	35.5	0	0	0	112.2	Y336 F337 E338 V348	P334-Y336 PolarHBondContact O-N 3.19Å; P334-F337 PolarHBondContact O-N 3.04Å; P334-E338 WeakPolarHBondContact O-CB 3.5Å; P334-E338 PolarHBondContact O-N 3.37Å; P334-V348 HydrophobicContact CB-CG1 3.76Å; P334-V348 HydrophobicContact CG-CG1 4.4Å
335	A	81.8	Confident	80.3	Confident	32 Å²	32	40.1 Å²	40.1	26%	0.264	22%	0.22	S	C	.	.	H	α-helix	trans	-61.7	-43.3	179.6	0	0	0	0	0	112.1	S332 Q333 F337 E338 E339 W476	S332-A335 PolarHBondContact O-N 3.37Å; Q333-A335 PolarHBondContact O-N 3.12Å; A335-F337 PolarHBondContact O-N 2.84Å; A335-E338 PolarHBondContact O-N 3.33Å; A335-E339 VanDerWaalsContact O-CB 3.32Å; A335-E339 WeakPolarHBondContact O-CB 3.4Å; A335-E339 VanDerWaalsContact O-CG 3.29Å; A335-E339 WeakPolarHBondContact O-CG 3.37Å; A335-E339 PolarHBondContact O-N 3.39Å; A335-W476 HydrophobicContact CB-CH2 4.2Å; A335-W476 HydrophobicContact CB-CZ2 4.14Å
336	Y	85.9	Confident	78.8	Confident	2 Å²	2	44.7 Å²	44.7	1%	0.008	25%	0.252	C	S	.	.	H	α-helix	trans	-60.1	-46.6	177.7	172.4	-113	0	0	0	112.4	S332 Q333 P334 E338 V340 F341 V403 W476 F480	S332-Y336 WeakPolarHBondContact O-CB 3.21Å; S332-Y336 PolarHBondContact O-N 2.74Å; Q333-Y336 PolarHBondContact O-N 2.79Å; P334-Y336 PolarHBondContact O-N 3.19Å; Y336-E338 VanDerWaalsContact C-N 3.34Å; Y336-E338 PolarHBondContact O-N 3.08Å; Y336-V340 HydrophobicContact CD2-CB 4.23Å; Y336-V340 HydrophobicContact CD2-CG2 3.65Å; Y336-V340 HydrophobicContact CE2-CB 4.05Å; Y336-V340 HydrophobicContact CE2-CG1 4.26Å; Y336-V340 HydrophobicContact CE2-CG2 3.65Å; Y336-V340 WeakPolarHBondContact O-CB 3.04Å; Y336-V340 PolarHBondContact O-N 3.18Å; Y336-F341 HydrophobicContact CE1-CD2 4.34Å; Y336-F341 AromaticContact CE1-CE2 3.71Å; Y336-F341 HydrophobicContact CE1-CE2 3.71Å; Y336-F341 AromaticContact CZ-CE2 3.68Å; Y336-V403 HydrophobicContact CE1-CG1 4.08Å; Y336-V403 PolarHBondContact OH-O 3.06Å; Y336-V403 VanDerWaalsContact OH-O 3.08Å; Y336-W476 HydrophobicContact CD2-CB 3.94Å; Y336-W476 AromaticContact CD2-CD2 3.63Å; Y336-W476 HydrophobicContact CD2-CD2 3.63Å; Y336-W476 AromaticContact CD2-CE3 3.78Å; Y336-W476 HydrophobicContact CD2-CE3 3.78Å; Y336-W476 AromaticContact CD2-CG 3.7Å; Y336-W476 HydrophobicContact CD2-CG 3.7Å; Y336-W476 HydrophobicContact CE2-CB 3.94Å; Y336-W476 HydrophobicContact CE2-CG 4.19Å; Y336-W476 HydrophobicContact CG-CD2 4.42Å; Y336-W476 HydrophobicContact CG-CE3 4.3Å; Y336-F480 HydrophobicContact CD1-CE2 4.21Å; Y336-F480 HydrophobicContact CD1-CZ 4.2Å; Y336-F480 AromaticContact CD2-CE2 3.76Å; Y336-F480 HydrophobicContact CD2-CE2 3.76Å; Y336-F480 HydrophobicContact CD2-CZ 4.43Å; Y336-F480 HydrophobicContact CE1-CE2 4.1Å; Y336-F480 HydrophobicContact CE1-CZ 4.29Å; Y336-F480 HydrophobicContact CE2-CD2 4.42Å; Y336-F480 AromaticContact CE2-CE2 3.63Å; Y336-F480 HydrophobicContact CE2-CE2 3.63Å; Y336-F480 HydrophobicContact CG-CE2 4.03Å; Y336-F480 HydrophobicContact CG-CZ 4.25Å; Y336-F480 AromaticContact CZ-CE2 3.81Å
337	F	83.9	Confident	77.8	Confident	3 Å²	3	48.3 Å²	48.3	1%	0.013	27%	0.267	C	S	.	.	H	α-helix	trans	-70.4	-30.8	-179.9	-77	-63.6	0	0	0	113.2	Q333 P334 A335 F341 G342 F343 A412 I413 L416	Q333-F337 HydrophobicContact CG-CD2 3.83Å; Q333-F337 HydrophobicContact CG-CE2 3.7Å; Q333-F337 VanDerWaalsContact O-CD2 3.23Å; Q333-F337 WeakPolarHBondContact O-CD2 3.25Å; Q333-F337 PolarHBondContact O-N 3.23Å; P334-F337 PolarHBondContact O-N 3.04Å; A335-F337 PolarHBondContact O-N 2.84Å; F337-F341 AromaticContact CD1-CD2 3.76Å; F337-F341 HydrophobicContact CD1-CD2 3.76Å; F337-F341 HydrophobicContact CD1-CE2 4.31Å; F337-F341 HydrophobicContact CE1-CD2 4.22Å; F337-F341 HydrophobicContact CE1-CE2 4.34Å; F337-F341 WeakPolarHBondContact O-CB 3.25Å; F337-F341 PolarHBondContact O-N 3.43Å; F337-G342 PolarHBondContact O-N 3.46Å; F337-F343 HydrophobicContact CB-CB 4.34Å; F337-F343 PolarHBondContact O-N 3.08Å; F337-F343 VanDerWaalsContact O-N 3.11Å; F337-A412 HydrophobicContact CE1-CB 3.95Å; F337-I413 HydrophobicContact CD1-CG1 4.43Å; F337-I413 HydrophobicContact CE1-CD1 4.44Å; F337-I413 HydrophobicContact CE1-CG1 3.56Å; F337-I413 HydrophobicContact CZ-CG1 3.71Å; F337-L416 HydrophobicContact CE2-CD1 3.92Å; F337-L416 HydrophobicContact CZ-CD1 4.04Å
338	E	81.4	Confident	76.9	Confident	94 Å²	94	47.5 Å²	47.5	44%	0.439	27%	0.265	S	S	.	.	H	α-helix	trans	-70.8	-54.1	173.4	-174	177	-178.6	0	0	111.2	P334 A335 Y336 G342	P334-E338 WeakPolarHBondContact O-CB 3.5Å; P334-E338 PolarHBondContact O-N 3.37Å; A335-E338 PolarHBondContact O-N 3.33Å; Y336-E338 VanDerWaalsContact C-N 3.34Å; Y336-E338 PolarHBondContact O-N 3.08Å; E338-G342 WeakPolarHBondContact O-CA 3.43Å; E338-G342 PolarHBondContact O-N 3.38Å
339	E	85.2	Confident	75.9	Confident	55 Å²	55	49.3 Å²	49.3	26%	0.257	29%	0.285	S	S	.	.	H	α-helix	trans	-72.3	-40.5	-172	-67.1	179.4	171.9	0	0	113.4	A335 K471 W476	A335-E339 VanDerWaalsContact O-CB 3.32Å; A335-E339 WeakPolarHBondContact O-CB 3.4Å; A335-E339 VanDerWaalsContact O-CG 3.29Å; A335-E339 WeakPolarHBondContact O-CG 3.37Å; A335-E339 PolarHBondContact O-N 3.39Å; E339-K471 HydrophobicContact CB-CB 4.47Å; E339-K471 HydrophobicContact CG-CB 4.29Å; E339-K471 HydrophobicContact CG-CD 4.39Å; E339-K471 HydrophobicContact CG-CG 4.44Å; E339-K471 WeakPolarHBondContact OE1-CD 3.22Å; E339-K471 WeakPolarHBondContact OE1-CG 3.31Å; E339-K471 IonicContact OE1-NZ 2.88Å; E339-K471 PolarHBondContact OE1-NZ 3.45Å; E339-W476 WeakPolarHBondContact OE2-CZ2 3.39Å; E339-W476 PolarHBondContact OE2-NE1 3.42Å
340	V	86.6	Confident	75.3	Confident	33 Å²	33	56 Å²	56	20%	0.2	32%	0.317	C	S	.	.	H	α-helix	trans	-89.1	-37.5	-175.4	178.9	0	0	0	0	112.3	Y336 R473 W476	Y336-V340 HydrophobicContact CD2-CB 4.23Å; Y336-V340 HydrophobicContact CD2-CG2 3.65Å; Y336-V340 HydrophobicContact CE2-CB 4.05Å; Y336-V340 HydrophobicContact CE2-CG1 4.26Å; Y336-V340 HydrophobicContact CE2-CG2 3.65Å; Y336-V340 WeakPolarHBondContact O-CB 3.04Å; Y336-V340 PolarHBondContact O-N 3.18Å; V340-R473 HydrophobicContact CG1-CG 4.04Å; V340-W476 HydrophobicContact CG2-CB 4.23Å; V340-W476 VanDerWaalsContact CG2-CD1 3.41Å; V340-W476 HydrophobicContact CG2-CG 3.88Å
341	F	84.1	Confident	75.1	Confident	17 Å²	17	54.5 Å²	54.5	8%	0.075	31%	0.309	C	S	.	.	H	α-helix	trans	-111.1	-9.4	-171.8	-66.4	-70.3	0	0	0	114.4	Y336 F337 F343 R409 A412	Y336-F341 HydrophobicContact CE1-CD2 4.34Å; Y336-F341 AromaticContact CE1-CE2 3.71Å; Y336-F341 HydrophobicContact CE1-CE2 3.71Å; Y336-F341 AromaticContact CZ-CE2 3.68Å; F337-F341 AromaticContact CD1-CD2 3.76Å; F337-F341 HydrophobicContact CD1-CD2 3.76Å; F337-F341 HydrophobicContact CD1-CE2 4.31Å; F337-F341 HydrophobicContact CE1-CD2 4.22Å; F337-F341 HydrophobicContact CE1-CE2 4.34Å; F337-F341 WeakPolarHBondContact O-CB 3.25Å; F337-F341 PolarHBondContact O-N 3.43Å; F341-F343 VanDerWaalsContact C-N 3.33Å; F341-R409 HydrophobicContact CB-CG 4.03Å; F341-R409 HydrophobicContact CD1-CB 4.47Å; F341-R409 HydrophobicContact CD1-CG 3.56Å; F341-R409 HydrophobicContact CE1-CG 4.29Å; F341-R409 HydrophobicContact CG-CG 3.99Å; F341-R409 PolarHBondContact O-NE 2.7Å; F341-R409 VanDerWaalsContact O-NE 3.17Å; F341-R409 PolarHBondContact O-NH2 3Å; F341-A412 HydrophobicContact CE2-CB 3.72Å; F341-A412 HydrophobicContact CZ-CB 3.72Å
342	G	78.3	Confident	75.1	Confident	58 Å²	58	51.6 Å²	51.6	60%	0.598	30%	0.296	S	S	*	.			trans	65.4	32.9	-179.1	0	0	0	0	0	113.1	F337 E338	F337-G342 PolarHBondContact O-N 3.46Å; E338-G342 WeakPolarHBondContact O-CA 3.43Å; E338-G342 PolarHBondContact O-N 3.38Å
343	F	73.4	Confident	75.1	Confident	49 Å²	49	52 Å²	52	22%	0.215	30%	0.299	C	S	.	.			trans	-73.1	132.1	-179.2	-144.7	-101.7	0	0	0	110.5	F337 F341 I345 K347 V348 L351	F337-F343 HydrophobicContact CB-CB 4.34Å; F337-F343 PolarHBondContact O-N 3.08Å; F337-F343 VanDerWaalsContact O-N 3.11Å; F341-F343 VanDerWaalsContact C-N 3.33Å; F343-I345 PolarHBondContact O-N 3.07Å; F343-K347 HydrophobicContact CD1-CB 3.87Å; F343-K347 HydrophobicContact CE1-CB 3.31Å; F343-K347 HydrophobicContact CE1-CD 4.44Å; F343-K347 HydrophobicContact CZ-CB 4.19Å; F343-V348 HydrophobicContact CB-CG2 3.86Å; F343-V348 HydrophobicContact CD1-CG2 3.6Å; F343-V348 HydrophobicContact CG-CG2 4.19Å; F343-L351 HydrophobicContact CE1-CD2 3.98Å; F343-L351 HydrophobicContact CZ-CD2 4.17Å
344	E	69.2	Low	75.3	Confident	115 Å²	115	54.3 Å²	54.3	54%	0.537	31%	0.314	S	S	.	.			trans	-60.3	126.5	175.7	-70.1	173.7	146.2	0	0	110.5	S346 K347 V348	E344-S346 PolarHBondContact O-N 3.44Å; E344-K347 PolarHBondContact O-N 2.94Å; E344-K347 IonicContact OE2-NZ 2.8Å; E344-K347 PolarHBondContact OE2-NZ 3.38Å; E344-V348 PolarHBondContact O-N 3.41Å
345	I	58.9	Low	75.7	Confident	112 Å²	112	52.1 Å²	52.1	57%	0.574	30%	0.3	S	S	*	.	H	α-helix	trans	-49.2	-35.6	-178	-62.8	168.8	0	0	0	112.3	F343 K347 V348 G349	F343-I345 PolarHBondContact O-N 3.07Å; I345-K347 VanDerWaalsContact C-N 3.3Å; I345-K347 PolarHBondContact O-N 2.85Å; I345-V348 WeakPolarHBondContact O-CB 3.31Å; I345-V348 PolarHBondContact O-N 2.89Å; I345-G349 PolarHBondContact O-N 3.18Å
346	S	57.6	Low	75.8	Confident	95 Å²	95	51.3 Å²	51.3	66%	0.664	29%	0.291	S	S	*	.	H	α-helix	trans	-62.3	-33	179.4	60	0	0	0	0	113.6	E344	E344-S346 PolarHBondContact O-N 3.44Å
347	K	65.5	Low	76	Confident	108 Å²	108	55.1 Å²	55.1	47%	0.47	31%	0.311	S	S	.	.	H	α-helix	trans	-88.7	-25.6	176.2	-63.3	175.6	-177.6	141.4	0	112	F343 E344 I345 G349 L351	F343-K347 HydrophobicContact CD1-CB 3.87Å; F343-K347 HydrophobicContact CE1-CB 3.31Å; F343-K347 HydrophobicContact CE1-CD 4.44Å; F343-K347 HydrophobicContact CZ-CB 4.19Å; E344-K347 PolarHBondContact O-N 2.94Å; E344-K347 IonicContact OE2-NZ 2.8Å; E344-K347 PolarHBondContact OE2-NZ 3.38Å; I345-K347 VanDerWaalsContact C-N 3.3Å; I345-K347 PolarHBondContact O-N 2.85Å; K347-G349 VanDerWaalsContact C-N 3.27Å; K347-G349 PolarHBondContact O-N 3.27Å; K347-L351 WeakPolarHBondContact O-CB 3.15Å; K347-L351 PolarHBondContact O-N 3.4Å
348	V	64.6	Low	76.4	Confident	6 Å²	6	56.8 Å²	56.8	4%	0.036	32%	0.321	C	S	.	.	H	α-helix	trans	-60.3	-36.8	175.4	177.5	0	0	0	0	111.3	P334 F343 E344 I345 L351 S352	P334-V348 HydrophobicContact CB-CG1 3.76Å; P334-V348 HydrophobicContact CG-CG1 4.4Å; F343-V348 HydrophobicContact CB-CG2 3.86Å; F343-V348 HydrophobicContact CD1-CG2 3.6Å; F343-V348 HydrophobicContact CG-CG2 4.19Å; E344-V348 PolarHBondContact O-N 3.41Å; I345-V348 WeakPolarHBondContact O-CB 3.31Å; I345-V348 PolarHBondContact O-N 2.89Å; V348-L351 PolarHBondContact O-N 3.04Å; V348-S352 VanDerWaalsContact O-CB 3.28Å; V348-S352 WeakPolarHBondContact O-CB 3.49Å; V348-S352 PolarHBondContact O-N 3.43Å; V348-S352 PolarHBondContact O-OG 3.16Å
349	G	63.8	Low	76.9	Confident	42 Å²	42	52.4 Å²	52.4	43%	0.433	30%	0.3	S	S	.	.	H	α-helix	trans	-59.6	-52	-179.2	0	0	0	0	0	114	I345 K347 L351 S352 A353	I345-G349 PolarHBondContact O-N 3.18Å; K347-G349 VanDerWaalsContact C-N 3.27Å; K347-G349 PolarHBondContact O-N 3.27Å; G349-L351 VanDerWaalsContact C-N 3.33Å; G349-L351 PolarHBondContact O-N 3.3Å; G349-S352 PolarHBondContact O-N 3.04Å; G349-A353 PolarHBondContact O-N 2.91Å
350	M	70.9	Confident	77.2	Confident	149 Å²	149	51.1 Å²	51.1	73%	0.734	30%	0.296	S	S	*	.	H	α-helix	trans	-66.1	-38.2	176.9	-65.7	-168.3	-51.6	0	0	111.8	S352 A353	M350-S352 VanDerWaalsContact C-N 3.27Å; M350-S352 PolarHBondContact O-N 3.24Å; M350-A353 PolarHBondContact O-N 3.29Å
351	L	73.4	Confident	77.6	Confident	33 Å²	33	54 Å²	54	17%	0.173	31%	0.31	C	S	.	.	H	α-helix	trans	-65.3	-33.7	178.6	-170.7	65.6	0	0	0	112.1	F343 K347 V348 G349 A353 V354 P355 I413	F343-L351 HydrophobicContact CE1-CD2 3.98Å; F343-L351 HydrophobicContact CZ-CD2 4.17Å; K347-L351 WeakPolarHBondContact O-CB 3.15Å; K347-L351 PolarHBondContact O-N 3.4Å; V348-L351 PolarHBondContact O-N 3.04Å; G349-L351 VanDerWaalsContact C-N 3.33Å; G349-L351 PolarHBondContact O-N 3.3Å; L351-A353 VanDerWaalsContact C-N 3.26Å; L351-A353 PolarHBondContact O-N 3.4Å; L351-V354 PolarHBondContact O-N 3.48Å; L351-P355 WeakPolarHBondContact O-CD 3.46Å; L351-I413 HydrophobicContact CD1-CD1 4.23Å; L351-I413 HydrophobicContact CD1-CG2 3.72Å; L351-I413 HydrophobicContact CD2-CD1 3.51Å; L351-I413 HydrophobicContact CD2-CG1 3.91Å; L351-I413 HydrophobicContact CG-CD1 4.43Å; L351-I413 HydrophobicContact CG-CG2 4.43Å
352	S	72.9	Confident	78.1	Confident	14 Å²	14	55 Å²	55	10%	0.098	32%	0.315	C	S	.	.	H	α-helix	trans	-72.5	-18.4	178.4	-57	0	0	0	0	113.3	V348 G349 M350 P355 H356	V348-S352 VanDerWaalsContact O-CB 3.28Å; V348-S352 WeakPolarHBondContact O-CB 3.49Å; V348-S352 PolarHBondContact O-N 3.43Å; V348-S352 PolarHBondContact O-OG 3.16Å; G349-S352 PolarHBondContact O-N 3.04Å; M350-S352 VanDerWaalsContact C-N 3.27Å; M350-S352 PolarHBondContact O-N 3.24Å; S352-P355 WeakPolarHBondContact O-CD 3.01Å; S352-H356 PolarHBondContact O-CD2 3.25Å
353	A	79.7	Confident	78.9	Confident	18 Å²	18	52.2 Å²	52.2	15%	0.149	29%	0.287	C	S	.	.	H	α-helix	trans	-77.8	-26	174	0	0	0	0	0	113	G349 M350 L351 H356 L357	G349-A353 PolarHBondContact O-N 2.91Å; M350-A353 PolarHBondContact O-N 3.29Å; L351-A353 VanDerWaalsContact C-N 3.26Å; L351-A353 PolarHBondContact O-N 3.4Å; A353-H356 PolarHBondContact O-N 2.9Å; A353-L357 WeakPolarHBondContact O-CB 3.37Å; A353-L357 PolarHBondContact O-N 3.42Å
354	V	86.3	Confident	79.9	Confident	58 Å²	58	51.3 Å²	51.3	35%	0.352	29%	0.286	S	S	.	.	H	α-helix	trans	-60.2	-47.9	-174	-179.1	0	0	0	0	113	L351 H356 L357 V358 V417	L351-V354 PolarHBondContact O-N 3.48Å; V354-H356 VanDerWaalsContact C-N 3.33Å; V354-H356 PolarHBondContact O-N 3.25Å; V354-L357 WeakPolarHBondContact O-CB 3.45Å; V354-L357 PolarHBondContact O-N 2.78Å; V354-V358 WeakPolarHBondContact O-CG2 3.5Å; V354-V358 PolarHBondContact O-N 3.41Å; V354-V417 HydrophobicContact CB-CG2 4.4Å; V354-V417 HydrophobicContact CG1-CG1 4.16Å; V354-V417 HydrophobicContact CG1-CG2 3.81Å
355	P	85.8	Confident	81.2	Confident	1 Å²	1	49.4 Å²	49.4	1%	0.006	28%	0.279	C	S	.	.	H	α-helix	trans	-61.6	-41.7	179.7	-20.5	32.3	0	0	0	112.2	L351 S352 L357 V358 M359 L416 V417 V420	L351-P355 WeakPolarHBondContact O-CD 3.46Å; S352-P355 WeakPolarHBondContact O-CD 3.01Å; P355-L357 VanDerWaalsContact C-N 3.34Å; P355-L357 PolarHBondContact O-N 3.36Å; P355-V358 PolarHBondContact O-N 2.88Å; P355-M359 WeakPolarHBondContact O-CB 3.29Å; P355-M359 PolarHBondContact O-N 3.47Å; P355-L416 HydrophobicContact CB-CD2 3.98Å; P355-L416 HydrophobicContact CG-CD2 3.36Å; P355-V417 HydrophobicContact CG-CG2 4.19Å; P355-V420 HydrophobicContact CB-CB 3.8Å; P355-V420 HydrophobicContact CB-CG1 3.8Å; P355-V420 HydrophobicContact CB-CG2 3.77Å; P355-V420 VanDerWaalsContact O-CG1 3.24Å; P355-V420 WeakPolarHBondContact O-CG1 3.27Å
356	H	84.6	Confident	82.8	Confident	16 Å²	16	44 Å²	44	7%	0.074	25%	0.251	C	S	.	.	H	α-helix	trans	-67.4	-34	177.6	-62.5	-53.7	0	0	0	112.6	V227 S352 A353 V354 M359 T360	V227-H356 HydrophobicContact CG2-CB 3.51Å; S352-H356 PolarHBondContact O-CD2 3.25Å; A353-H356 PolarHBondContact O-N 2.9Å; V354-H356 VanDerWaalsContact C-N 3.33Å; V354-H356 PolarHBondContact O-N 3.25Å; H356-M359 PolarHBondContact O-N 2.97Å; H356-T360 PolarHBondContact O-N 2.92Å; H356-T360 PolarHBondContact O-OG1 3.47Å
357	L	90.3	Very high	84.5	Confident	82 Å²	82	39.5 Å²	39.5	43%	0.429	22%	0.22	S	C	.	.	H	α-helix	trans	-64.7	-47.6	173.2	-176.5	152.5	0	0	0	111	V227 A353 V354 P355 M359 T360 I361	V227-L357 HydrophobicContact CG1-CB 4.27Å; V227-L357 HydrophobicContact CG1-CD1 4.34Å; V227-L357 HydrophobicContact CG2-CB 4.2Å; A353-L357 WeakPolarHBondContact O-CB 3.37Å; A353-L357 PolarHBondContact O-N 3.42Å; V354-L357 WeakPolarHBondContact O-CB 3.45Å; V354-L357 PolarHBondContact O-N 2.78Å; P355-L357 VanDerWaalsContact C-N 3.34Å; P355-L357 PolarHBondContact O-N 3.36Å; L357-M359 VanDerWaalsContact C-N 3.3Å; L357-M359 PolarHBondContact O-N 2.91Å; L357-T360 WeakPolarHBondContact O-CB 3.39Å; L357-T360 PolarHBondContact O-N 3.27Å; L357-I361 HydrophobicContact CD2-CD1 3.77Å; L357-I361 PolarHBondContact O-N 3.09Å
358	V	92.6	Very high	85.9	Confident	37 Å²	37	38 Å²	38	22%	0.224	21%	0.214	C	C	.	.	H	α-helix	trans	-60.5	-43.4	176.3	173.4	0	0	0	0	110.5	V354 P355 T360 I361 I362 V417	V354-V358 WeakPolarHBondContact O-CG2 3.5Å; V354-V358 PolarHBondContact O-N 3.41Å; P355-V358 PolarHBondContact O-N 2.88Å; V358-T360 VanDerWaalsContact C-N 3.3Å; V358-T360 PolarHBondContact O-N 3.45Å; V358-I361 PolarHBondContact O-N 3.35Å; V358-I361 VanDerWaalsContact O-N 3.12Å; V358-I362 HydrophobicContact CG1-CG1 3.98Å; V358-I362 WeakPolarHBondContact O-CG1 3.47Å; V358-I362 PolarHBondContact O-N 3.39Å; V358-V417 HydrophobicContact CB-CG1 4.34Å; V358-V417 HydrophobicContact CG2-CG1 3.69Å
359	M	91.1	Very high	87.3	Confident	2 Å²	2	40.9 Å²	40.9	1%	0.01	23%	0.229	C	C	.	.	H	α-helix	trans	-59.3	-41.4	176.4	-162.5	175.1	-170.4	0	0	112.5	Y223 P355 H356 L357 I361 I362 V363 V420 I427	Y223-M359 HydrophobicContact CD1-CG 4.46Å; Y223-M359 HydrophobicContact CD1-SD 3.71Å; Y223-M359 HydrophobicContact CD2-CG 4.29Å; Y223-M359 HydrophobicContact CD2-SD 4.28Å; Y223-M359 HydrophobicContact CE1-CE 3.96Å; Y223-M359 HydrophobicContact CE1-SD 3.37Å; Y223-M359 WeakPolarHBondContact CE1-SD 3.09Å; Y223-M359 HydrophobicContact CE2-CE 3.9Å; Y223-M359 HydrophobicContact CE2-CG 4.34Å; Y223-M359 HydrophobicContact CE2-SD 4Å; Y223-M359 HydrophobicContact CG-CG 4.34Å; Y223-M359 HydrophobicContact CG-SD 4.15Å; Y223-M359 VanDerWaalsContact CZ-CE 3.47Å; Y223-M359 VanDerWaalsContact CZ-SD 3.51Å; Y223-M359 WeakPolarHBondContact OH-CE 3.36Å; P355-M359 WeakPolarHBondContact O-CB 3.29Å; P355-M359 PolarHBondContact O-N 3.47Å; H356-M359 PolarHBondContact O-N 2.97Å; L357-M359 VanDerWaalsContact C-N 3.3Å; L357-M359 PolarHBondContact O-N 2.91Å; M359-I361 PolarHBondContact O-N 2.87Å; M359-I362 PolarHBondContact O-N 3.37Å; M359-V363 HydrophobicContact CE-CG2 4.06Å; M359-V363 HydrophobicContact CG-CG2 3.91Å; M359-V363 WeakPolarHBondContact O-CB 3.26Å; M359-V363 WeakPolarHBondContact O-CG2 3.29Å; M359-V363 PolarHBondContact O-N 3.38Å; M359-V420 HydrophobicContact CB-CG1 3.95Å; M359-V420 HydrophobicContact CG-CG1 4.44Å; M359-V420 HydrophobicContact SD-CG1 4.34Å; M359-I427 HydrophobicContact CE-CD1 4.1Å; M359-I427 HydrophobicContact CE-CG1 3.7Å
360	T	92.5	Very high	88.7	Confident	28 Å²	28	38.9 Å²	38.9	17%	0.172	21%	0.208	C	C	.	.	H	α-helix	trans	-58.4	-35.8	177.8	-57.5	0	0	0	0	111.8	Y223 A224 H356 L357 V358 P364	Y223-T360 VanDerWaalsContact CB-OG1 3.24Å; Y223-T360 WeakPolarHBondContact CB-OG1 3.29Å; A224-T360 HydrophobicContact CB-CG2 3.75Å; A224-T360 PolarHBondContact N-OG1 3.49Å; H356-T360 PolarHBondContact O-N 2.92Å; H356-T360 PolarHBondContact O-OG1 3.47Å; L357-T360 WeakPolarHBondContact O-CB 3.39Å; L357-T360 PolarHBondContact O-N 3.27Å; V358-T360 VanDerWaalsContact C-N 3.3Å; V358-T360 PolarHBondContact O-N 3.45Å; T360-P364 WeakPolarHBondContact O-CD 3.25Å
361	I	94.4	Very high	89.6	Confident	95 Å²	95	32.2 Å²	32.2	49%	0.487	18%	0.175	S	C	.	.	H	α-helix	trans	-80.6	-43.8	179.5	-62.9	171.4	0	0	0	111.3	L357 V358 M359 P364 I365	L357-I361 HydrophobicContact CD2-CD1 3.77Å; L357-I361 PolarHBondContact O-N 3.09Å; V358-I361 PolarHBondContact O-N 3.35Å; V358-I361 VanDerWaalsContact O-N 3.12Å; M359-I361 PolarHBondContact O-N 2.87Å; I361-P364 WeakPolarHBondContact O-CD 3.12Å; I361-I365 HydrophobicContact CG2-CD1 3.87Å; I361-I365 WeakPolarHBondContact O-CD1 3.37Å; I361-I365 WeakPolarHBondContact O-CG1 3.43Å
362	I	95.2	Very high	90.6	Very high	36 Å²	36	36.2 Å²	36.2	19%	0.185	19%	0.192	C	C	.	.	H	α-helix	trans	-73	-34.3	-174.4	-62.4	-64.8	0	0	0	112.4	V358 M359 I365 G366 G421 F425	V358-I362 HydrophobicContact CG1-CG1 3.98Å; V358-I362 WeakPolarHBondContact O-CG1 3.47Å; V358-I362 PolarHBondContact O-N 3.39Å; M359-I362 PolarHBondContact O-N 3.37Å; I362-I365 HydrophobicContact CD1-CD1 4.43Å; I362-I365 WeakPolarHBondContact O-CB 3.47Å; I362-I365 PolarHBondContact O-N 3.2Å; I362-I365 VanDerWaalsContact O-N 3.15Å; I362-G366 PolarHBondContact O-N 2.91Å; I362-G421 VanDerWaalsContact CG2-O 3.26Å; I362-G421 WeakPolarHBondContact CG2-O 3.44Å; I362-F425 HydrophobicContact CG2-CD1 4.12Å; I362-F425 HydrophobicContact CG2-CD2 4.03Å; I362-F425 HydrophobicContact CG2-CE1 3.83Å; I362-F425 HydrophobicContact CG2-CE2 3.74Å; I362-F425 HydrophobicContact CG2-CG 4.21Å; I362-F425 HydrophobicContact CG2-CZ 3.62Å
363	V	94.4	Very high	91.5	Very high	0 Å²	0	37.2 Å²	37.2	0%	0	20%	0.195	C	C	.	.	H	α-helix	trans	-58.1	-50.2	-177.7	165.4	0	0	0	0	112.7	T216 C220 Y223 M359 I365 G366 G367 I427	T216-V363 WeakPolarHBondContact CB-O 3.45Å; T216-V363 HydrophobicContact CG2-CG1 4.15Å; C220-V363 HydrophobicContact CB-CG1 4.38Å; Y223-V363 HydrophobicContact CD2-CG2 4.41Å; Y223-V363 HydrophobicContact CE2-CG2 4.09Å; M359-V363 HydrophobicContact CE-CG2 4.06Å; M359-V363 HydrophobicContact CG-CG2 3.91Å; M359-V363 WeakPolarHBondContact O-CB 3.26Å; M359-V363 WeakPolarHBondContact O-CG2 3.29Å; M359-V363 PolarHBondContact O-N 3.38Å; V363-I365 PolarHBondContact O-N 2.97Å; V363-G366 PolarHBondContact O-N 3.31Å; V363-G367 PolarHBondContact O-N 2.9Å; V363-G367 VanDerWaalsContact O-N 3.12Å; V363-I427 HydrophobicContact CG1-CB 4.21Å; V363-I427 HydrophobicContact CG1-CG2 3.93Å; V363-I427 HydrophobicContact CG2-CB 4.15Å; V363-I427 HydrophobicContact CG2-CG1 3.92Å
364	P	94.4	Very high	92.1	Very high	30 Å²	30	37 Å²	37	20%	0.195	19%	0.191	C	C	.	.	H	α-helix	trans	-59.4	-43.2	172.8	-26.7	35.9	0	0	0	113	C220 T360 I361 G366 G367 Q368	C220-P364 HydrophobicContact CB-CG 3.63Å; T360-P364 WeakPolarHBondContact O-CD 3.25Å; I361-P364 WeakPolarHBondContact O-CD 3.12Å; P364-G366 VanDerWaalsContact C-N 3.32Å; P364-G366 PolarHBondContact O-N 2.93Å; P364-G367 PolarHBondContact O-N 3.14Å; P364-G367 VanDerWaalsContact O-N 3.09Å; P364-Q368 VanDerWaalsContact O-CG 3.29Å; P364-Q368 WeakPolarHBondContact O-CG 3.25Å; P364-Q368 PolarHBondContact O-N 3.29Å
365	I	95.3	Very high	92.2	Very high	75 Å²	75	37 Å²	37	39%	0.385	19%	0.194	S	C	.	.	H	α-helix	trans	-59.3	-44.4	178.3	-64.6	170	0	0	0	110.5	I361 I362 V363 G367 Q368 I369	I361-I365 HydrophobicContact CG2-CD1 3.87Å; I361-I365 WeakPolarHBondContact O-CD1 3.37Å; I361-I365 WeakPolarHBondContact O-CG1 3.43Å; I362-I365 HydrophobicContact CD1-CD1 4.43Å; I362-I365 WeakPolarHBondContact O-CB 3.47Å; I362-I365 PolarHBondContact O-N 3.2Å; I362-I365 VanDerWaalsContact O-N 3.15Å; V363-I365 PolarHBondContact O-N 2.97Å; I365-G367 VanDerWaalsContact C-N 3.29Å; I365-G367 PolarHBondContact O-N 3.23Å; I365-Q368 WeakPolarHBondContact O-CB 3.2Å; I365-Q368 PolarHBondContact O-N 3.02Å; I365-I369 HydrophobicContact CG2-CD1 3.76Å; I365-I369 HydrophobicContact CG2-CG1 4.36Å; I365-I369 WeakPolarHBondContact O-CG1 3.39Å; I365-I369 PolarHBondContact O-N 2.83Å
366	G	94	Very high	92.4	Very high	0 Å²	0	43.4 Å²	43.4	0%	0	22%	0.221	C	C	.	.	H	α-helix	trans	-61.9	-34.4	175.8	0	0	0	0	0	113.4	I362 V363 P364 A370 S428	I362-G366 PolarHBondContact O-N 2.91Å; V363-G366 PolarHBondContact O-N 3.31Å; P364-G366 VanDerWaalsContact C-N 3.32Å; P364-G366 PolarHBondContact O-N 2.93Å; G366-A370 WeakPolarHBondContact O-CB 3.31Å; G366-A370 PolarHBondContact O-N 3.47Å; G366-A370 VanDerWaalsContact O-N 3.08Å; G366-S428 VanDerWaalsContact C-OG 3.31Å; G366-S428 WeakPolarHBondContact O-CB 3.23Å; G366-S428 PolarHBondContact O-OG 3.3Å; G366-S428 VanDerWaalsContact O-OG 3.04Å
367	G	93	Very high	92.4	Very high	0 Å²	0	50 Å²	50	0%	0	25%	0.252	C	S	.	.	H	α-helix	trans	-68	-42.3	172.5	0	0	0	0	0	113	V363 P364 I365 A370 D371	V363-G367 PolarHBondContact O-N 2.9Å; V363-G367 VanDerWaalsContact O-N 3.12Å; P364-G367 PolarHBondContact O-N 3.14Å; P364-G367 VanDerWaalsContact O-N 3.09Å; I365-G367 VanDerWaalsContact C-N 3.29Å; I365-G367 PolarHBondContact O-N 3.23Å; G367-A370 PolarHBondContact O-N 2.81Å; G367-D371 PolarHBondContact O-N 3.46Å
368	Q	94.3	Very high	92.5	Very high	76 Å²	76	50.8 Å²	50.8	36%	0.355	26%	0.256	S	S	.	.	H	α-helix	trans	-63.1	-44.8	176.8	-63.6	-77.7	3.4	0	0	111.7	R213 P364 I365 D371 F372	R213-Q368 VanDerWaalsContact CD-OE1 3.22Å; P364-Q368 VanDerWaalsContact O-CG 3.29Å; P364-Q368 WeakPolarHBondContact O-CG 3.25Å; P364-Q368 PolarHBondContact O-N 3.29Å; I365-Q368 WeakPolarHBondContact O-CB 3.2Å; I365-Q368 PolarHBondContact O-N 3.02Å; Q368-D371 PolarHBondContact O-N 3.33Å; Q368-F372 VanDerWaalsContact O-CB 3.25Å; Q368-F372 WeakPolarHBondContact O-CB 3.33Å; Q368-F372 PolarHBondContact O-N 3.17Å
369	I	94.4	Very high	92.4	Very high	66 Å²	66	51.7 Å²	51.7	34%	0.338	26%	0.259	S	S	.	.	H	α-helix	trans	-62.8	-44.3	177.2	-67.1	168.4	0	0	0	110.3	I365 D371 F372 L373 M388 F425	I365-I369 HydrophobicContact CG2-CD1 3.76Å; I365-I369 HydrophobicContact CG2-CG1 4.36Å; I365-I369 WeakPolarHBondContact O-CG1 3.39Å; I365-I369 PolarHBondContact O-N 2.83Å; I369-D371 PolarHBondContact O-N 2.82Å; I369-F372 PolarHBondContact O-N 3.18Å; I369-L373 HydrophobicContact CG2-CD1 3.78Å; I369-L373 HydrophobicContact CG2-CG 4.41Å; I369-L373 VanDerWaalsContact O-CG 3.31Å; I369-L373 WeakPolarHBondContact O-CG 3.29Å; I369-L373 PolarHBondContact O-N 3.49Å; I369-M388 HydrophobicContact CG2-CE 3.76Å; I369-F425 HydrophobicContact CD1-CE1 4.14Å
370	A	92.6	Very high	92.5	Very high	0 Å²	0	54.8 Å²	54.8	0%	0	28%	0.281	C	S	.	.	H	α-helix	trans	-59.5	-46.2	178.8	0	0	0	0	0	111.9	G366 G367 R374 V384 M388	G366-A370 WeakPolarHBondContact O-CB 3.31Å; G366-A370 PolarHBondContact O-N 3.47Å; G366-A370 VanDerWaalsContact O-N 3.08Å; G367-A370 PolarHBondContact O-N 2.81Å; A370-R374 WeakPolarHBondContact O-CG 3.21Å; A370-R374 PolarHBondContact O-N 3.02Å; A370-V384 HydrophobicContact CB-CG1 3.74Å; A370-M388 HydrophobicContact CB-CG 4.4Å
371	D	91.3	Very high	92.3	Very high	9 Å²	9	55.1 Å²	55.1	5%	0.048	28%	0.283	C	S	.	.	H	α-helix	trans	-75.1	-31.1	179.2	-74.3	-11.8	0	0	0	112.5	L209 E210 S212 R213 G367 Q368 I369 R374 S375	L209-D371 VanDerWaalsContact O-CB 3.29Å; L209-D371 WeakPolarHBondContact O-CB 3.34Å; E210-D371 WeakPolarHBondContact CA-OD2 3.44Å; S212-D371 WeakPolarHBondContact CB-OD1 3.31Å; S212-D371 WeakPolarHBondContact CB-OD2 3.44Å; S212-D371 PolarHBondContact N-OD2 2.85Å; S212-D371 VanDerWaalsContact N-OD2 3.14Å; S212-D371 PolarHBondContact OG-OD1 3.41Å; R213-D371 VanDerWaalsContact CB-OD2 3.31Å; R213-D371 WeakPolarHBondContact CB-OD2 3.49Å; R213-D371 PolarHBondContact N-OD2 3.4Å; G367-D371 PolarHBondContact O-N 3.46Å; Q368-D371 PolarHBondContact O-N 3.33Å; I369-D371 PolarHBondContact O-N 2.82Å; D371-R374 PolarHBondContact O-N 3.46Å; D371-R374 IonicContact OD1-NH1 2.78Å; D371-R374 PolarHBondContact OD1-NH1 3.08Å; D371-S375 WeakPolarHBondContact O-CB 3.15Å; D371-S375 PolarHBondContact O-N 3.37Å; D371-S375 PolarHBondContact O-OG 3.16Å
372	F	92.5	Very high	92.2	Very high	118 Å²	118	51.8 Å²	51.8	52%	0.518	27%	0.267	S	S	.	.	H	α-helix	trans	-61.1	-47.4	172.1	176.4	-98.2	0	0	0	111.7	Q368 I369 R374 S375 K376 I378	Q368-F372 VanDerWaalsContact O-CB 3.25Å; Q368-F372 WeakPolarHBondContact O-CB 3.33Å; Q368-F372 PolarHBondContact O-N 3.17Å; I369-F372 PolarHBondContact O-N 3.18Å; F372-R374 VanDerWaalsContact C-N 3.29Å; F372-R374 PolarHBondContact O-N 2.63Å; F372-S375 WeakPolarHBondContact CA-OG 3.29Å; F372-S375 PolarHBondContact O-OG 2.95Å; F372-K376 HydrophobicContact CD2-CG 4.22Å; F372-K376 HydrophobicContact CE2-CG 3.92Å; F372-K376 HydrophobicContact CZ-CG 4.1Å; F372-K376 WeakPolarHBondContact O-CB 3.41Å; F372-K376 WeakPolarHBondContact O-CG 3.35Å; F372-K376 PolarHBondContact O-N 2.99Å; F372-K376 VanDerWaalsContact O-N 3.08Å; F372-I378 HydrophobicContact CE1-CD1 4.41Å
373	L	92.7	Very high	92.1	Very high	34 Å²	34	52.7 Å²	52.7	18%	0.178	27%	0.274	C	S	.	.	H	α-helix	trans	-63.1	-36	179	-70.7	164.2	0	0	0	112.3	I369 I378 L379 V384 M388	I369-L373 HydrophobicContact CG2-CD1 3.78Å; I369-L373 HydrophobicContact CG2-CG 4.41Å; I369-L373 VanDerWaalsContact O-CG 3.31Å; I369-L373 WeakPolarHBondContact O-CG 3.29Å; I369-L373 PolarHBondContact O-N 3.49Å; L373-I378 HydrophobicContact CD2-CB 4.47Å; L373-I378 HydrophobicContact CD2-CD1 4.3Å; L373-I378 HydrophobicContact CD2-CG2 4.43Å; L373-I378 PolarHBondContact O-N 2.95Å; L373-L379 HydrophobicContact CD1-CD1 4.3Å; L373-L379 HydrophobicContact CD2-CD1 4.28Å; L373-L379 PolarHBondContact O-N 2.96Å; L373-V384 HydrophobicContact CB-CG2 3.98Å; L373-M388 HydrophobicContact CD1-CE 3.48Å; L373-M388 VanDerWaalsContact CD1-CE 3.48Å
374	R	91.5	Very high	92	Very high	13 Å²	13	52.7 Å²	52.7	5%	0.049	27%	0.274	C	S	.	.	H	α-helix	trans	-77.3	-47.2	178.1	-69.9	173.7	66.3	-132.1	2.6	112.6	P208 L209 A370 D371 F372 K376 Q377 T381 V384	P208-R374 PolarHBondContact O-NH1 3.08Å; P208-R374 PolarHBondContact O-NH2 3.01Å; L209-R374 HydrophobicContact CD2-CB 4.42Å; A370-R374 WeakPolarHBondContact O-CG 3.21Å; A370-R374 PolarHBondContact O-N 3.02Å; D371-R374 PolarHBondContact O-N 3.46Å; D371-R374 IonicContact OD1-NH1 2.78Å; D371-R374 PolarHBondContact OD1-NH1 3.08Å; F372-R374 VanDerWaalsContact C-N 3.29Å; F372-R374 PolarHBondContact O-N 2.63Å; R374-K376 VanDerWaalsContact C-N 3.29Å; R374-K376 PolarHBondContact O-N 3Å; R374-Q377 WeakPolarHBondContact O-CA 3.15Å; R374-Q377 PolarHBondContact O-N 2.86Å; R374-Q377 PolarHBondContact O-NE2 3.49Å; R374-T381 PolarHBondContact NE-OG1 3.24Å; R374-T381 VanDerWaalsContact NE-OG1 3.07Å; R374-T381 PolarHBondContact NH2-OG1 3.35Å; R374-V384 HydrophobicContact CG-CB 4.19Å; R374-V384 HydrophobicContact CG-CG1 4.38Å; R374-V384 HydrophobicContact CG-CG2 3.85Å
375	S	88.6	Confident	92	Very high	59 Å²	59	51.3 Å²	51.3	41%	0.413	27%	0.265	S	S	.	.	H	α-helix	trans	-64.5	-33.2	-178.8	57.9	0	0	0	0	112.6	D371 F372 Q377	D371-S375 WeakPolarHBondContact O-CB 3.15Å; D371-S375 PolarHBondContact O-N 3.37Å; D371-S375 PolarHBondContact O-OG 3.16Å; F372-S375 WeakPolarHBondContact CA-OG 3.29Å; F372-S375 PolarHBondContact O-OG 2.95Å; S375-Q377 PolarHBondContact O-N 2.89Å
376	K	90.1	Very high	92	Very high	135 Å²	135	50.4 Å²	50.4	59%	0.587	26%	0.259	S	S	*	.	T	Hydrogen-bonded Turn	trans	-80.7	3	172.5	-65.7	-64.8	-174.4	-177.5	0	114.1	F372 R374 I378	F372-K376 HydrophobicContact CD2-CG 4.22Å; F372-K376 HydrophobicContact CE2-CG 3.92Å; F372-K376 HydrophobicContact CZ-CG 4.1Å; F372-K376 WeakPolarHBondContact O-CB 3.41Å; F372-K376 WeakPolarHBondContact O-CG 3.35Å; F372-K376 PolarHBondContact O-N 2.99Å; F372-K376 VanDerWaalsContact O-N 3.08Å; R374-K376 VanDerWaalsContact C-N 3.29Å; R374-K376 PolarHBondContact O-N 3Å; K376-I378 HydrophobicContact CB-CD1 3.79Å; K376-I378 HydrophobicContact CB-CG1 3.76Å; K376-I378 PolarHBondContact O-N 2.96Å; K376-I378 VanDerWaalsContact O-N 3.16Å
377	Q	86.1	Confident	92	Very high	154 Å²	154	54.4 Å²	54.4	72%	0.72	28%	0.279	S	S	*	.	T	Hydrogen-bonded Turn	trans	55.1	29.2	-179	-59.3	-65.6	-44	0	0	113.4	R374 S375	R374-Q377 WeakPolarHBondContact O-CA 3.15Å; R374-Q377 PolarHBondContact O-N 2.86Å; R374-Q377 PolarHBondContact O-NE2 3.49Å; S375-Q377 PolarHBondContact O-N 2.89Å
378	I	90.8	Very high	92	Very high	100 Å²	100	55.2 Å²	55.2	51%	0.513	28%	0.283	S	S	.	.	S	Bend	trans	-76.8	-38.5	179.5	-57.3	171.5	0	0	0	109.6	F372 L373 K376	F372-I378 HydrophobicContact CE1-CD1 4.41Å; L373-I378 HydrophobicContact CD2-CB 4.47Å; L373-I378 HydrophobicContact CD2-CD1 4.3Å; L373-I378 HydrophobicContact CD2-CG2 4.43Å; L373-I378 PolarHBondContact O-N 2.95Å; K376-I378 HydrophobicContact CB-CD1 3.79Å; K376-I378 HydrophobicContact CB-CG1 3.76Å; K376-I378 PolarHBondContact O-N 2.96Å; K376-I378 VanDerWaalsContact O-N 3.16Å
379	L	91.4	Very high	92	Very high	56 Å²	56	51.6 Å²	51.6	29%	0.293	27%	0.266	S	S	.	.	S	Bend	trans	-138.3	147	-177.9	-64.8	174.8	0	0	0	110.8	L373 T383 V384 I387	L373-L379 HydrophobicContact CD1-CD1 4.3Å; L373-L379 HydrophobicContact CD2-CD1 4.28Å; L373-L379 PolarHBondContact O-N 2.96Å; L379-T383 HydrophobicContact CD2-CG2 4.02Å; L379-V384 HydrophobicContact CB-CG2 3.47Å; L379-V384 VanDerWaalsContact CB-CG2 3.47Å; L379-V384 HydrophobicContact CD1-CG2 4.05Å; L379-V384 HydrophobicContact CG-CG2 4.42Å; L379-I387 HydrophobicContact CD1-CD1 3.91Å
380	S	92.4	Very high	91.9	Very high	66 Å²	66	49.8 Å²	49.8	46%	0.462	26%	0.259	S	S	.	.			trans	-68.8	158.2	173.4	71	0	0	0	0	111.9	T382 T383 V384	S380-T382 VanDerWaalsContact C-N 3.33Å; S380-T382 PolarHBondContact O-N 3.48Å; S380-T383 PolarHBondContact O-N 3.15Å; S380-T383 VanDerWaalsContact O-N 3.17Å; S380-T383 WeakPolarHBondContact OG-CB 3.43Å; S380-T383 PolarHBondContact OG-N 2.81Å; S380-T383 PolarHBondContact OG-OG1 3.16Å; S380-V384 WeakPolarHBondContact O-CG2 3.29Å; S380-V384 PolarHBondContact O-N 3.48Å
381	T	89.4	Confident	91.8	Very high	36 Å²	36	51.8 Å²	51.8	22%	0.221	28%	0.279	C	S	.	.	H	α-helix	trans	-53.6	-49.7	178.7	-56.8	0	0	0	0	111.3	R374 T383 V384 R385 D436	R374-T381 PolarHBondContact NE-OG1 3.24Å; R374-T381 VanDerWaalsContact NE-OG1 3.07Å; R374-T381 PolarHBondContact NH2-OG1 3.35Å; T381-T383 PolarHBondContact O-N 3.28Å; T381-V384 PolarHBondContact O-N 3.39Å; T381-R385 HydrophobicContact CG2-CG 4.35Å; T381-R385 WeakPolarHBondContact O-CG 3.41Å; T381-R385 PolarHBondContact O-N 3.05Å; T381-D436 HydrophobicContact CG2-CB 4.4Å
382	T	91.4	Very high	91.9	Very high	24 Å²	24	51.4 Å²	51.4	15%	0.147	28%	0.278	C	S	.	.	H	α-helix	trans	-57.2	-46.8	178.5	-55.6	0	0	0	0	112.1	S380 R385 K386 G500	S380-T382 VanDerWaalsContact C-N 3.33Å; S380-T382 PolarHBondContact O-N 3.48Å; T382-R385 PolarHBondContact O-N 3.46Å; T382-K386 HydrophobicContact CG2-CD 4.21Å; T382-K386 WeakPolarHBondContact O-CB 3.11Å; T382-K386 WeakPolarHBondContact O-CG 3.06Å; T382-K386 PolarHBondContact O-N 2.93Å; T382-G500 WeakPolarHBondContact OG1-CA 3.47Å; T382-G500 PolarHBondContact OG1-N 3.3Å
383	T	93.3	Very high	91.9	Very high	55 Å²	55	45.8 Å²	45.8	34%	0.337	25%	0.253	S	S	.	.	H	α-helix	trans	-65.4	-41.6	-179.1	-59.6	0	0	0	0	111.4	L379 S380 T381 K386 I387	L379-T383 HydrophobicContact CD2-CG2 4.02Å; S380-T383 PolarHBondContact O-N 3.15Å; S380-T383 VanDerWaalsContact O-N 3.17Å; S380-T383 WeakPolarHBondContact OG-CB 3.43Å; S380-T383 PolarHBondContact OG-N 2.81Å; S380-T383 PolarHBondContact OG-OG1 3.16Å; T381-T383 PolarHBondContact O-N 3.28Å; T383-K386 PolarHBondContact O-N 3.49Å; T383-I387 HydrophobicContact CG2-CD1 3.69Å; T383-I387 HydrophobicContact CG2-CG1 4.32Å; T383-I387 WeakPolarHBondContact O-CB 3.45Å; T383-I387 VanDerWaalsContact O-CG1 3.29Å; T383-I387 WeakPolarHBondContact O-CG1 3.48Å; T383-I387 PolarHBondContact O-N 3.47Å
384	V	93.6	Very high	92	Very high	0 Å²	0	44.9 Å²	44.9	0%	0	25%	0.252	C	S	.	.	H	α-helix	trans	-62.3	-46.5	174.4	173.7	0	0	0	0	111.1	A370 L373 R374 L379 S380 T381 K386 I387 M388	A370-V384 HydrophobicContact CB-CG1 3.74Å; L373-V384 HydrophobicContact CB-CG2 3.98Å; R374-V384 HydrophobicContact CG-CB 4.19Å; R374-V384 HydrophobicContact CG-CG1 4.38Å; R374-V384 HydrophobicContact CG-CG2 3.85Å; L379-V384 HydrophobicContact CB-CG2 3.47Å; L379-V384 VanDerWaalsContact CB-CG2 3.47Å; L379-V384 HydrophobicContact CD1-CG2 4.05Å; L379-V384 HydrophobicContact CG-CG2 4.42Å; S380-V384 WeakPolarHBondContact O-CG2 3.29Å; S380-V384 PolarHBondContact O-N 3.48Å; T381-V384 PolarHBondContact O-N 3.39Å; V384-K386 VanDerWaalsContact C-N 3.32Å; V384-K386 PolarHBondContact O-N 3.35Å; V384-I387 PolarHBondContact O-N 3.22Å; V384-M388 HydrophobicContact CG1-CE 4.42Å; V384-M388 HydrophobicContact CG1-CG 4.08Å; V384-M388 WeakPolarHBondContact O-CB 3.32Å; V384-M388 WeakPolarHBondContact O-CG 3.24Å; V384-M388 PolarHBondContact O-N 2.89Å
385	R	93.5	Very high	92.1	Very high	1 Å²	1	48.2 Å²	48.2	0%	0.004	27%	0.269	C	S	.	.	H	α-helix	trans	-60.9	-40.9	178.1	-64.2	-43.8	-175.7	-160.6	-11.7	112.1	S212 T381 T382 N389 S428 G429 V432 D436	S212-R385 PolarHBondContact OG-NH1 2.89Å; S212-R385 PolarHBondContact OG-NH2 2.81Å; S212-R385 VanDerWaalsContact OG-NH2 3.09Å; T381-R385 HydrophobicContact CG2-CG 4.35Å; T381-R385 WeakPolarHBondContact O-CG 3.41Å; T381-R385 PolarHBondContact O-N 3.05Å; T382-R385 PolarHBondContact O-N 3.46Å; R385-N389 VanDerWaalsContact O-CB 3.25Å; R385-N389 WeakPolarHBondContact O-CB 3.38Å; R385-N389 PolarHBondContact O-N 3.36Å; R385-N389 VanDerWaalsContact O-N 3.09Å; R385-S428 PolarHBondContact NH1-O 3.46Å; R385-G429 WeakPolarHBondContact CD-O 3.39Å; R385-V432 VanDerWaalsContact NH2-CG1 3.28Å; R385-D436 IonicContact CZ-OD2 2.96Å; R385-D436 IonicContact NE-OD2 3.97Å; R385-D436 PolarHBondContact NE-OD2 2.93Å; R385-D436 IonicContact NH2-OD1 2.69Å; R385-D436 IonicContact NH2-OD2 2.86Å; R385-D436 PolarHBondContact NH2-OD2 3.34Å
386	K	94.3	Very high	92.4	Very high	57 Å²	57	45.4 Å²	45.4	25%	0.248	25%	0.25	C	C	.	.	H	α-helix	trans	-66.3	-47.9	176.7	-73.9	-175.3	-179.6	-167.2	0	111.6	T382 T383 V384 N389 C390 A495 A498	T382-K386 HydrophobicContact CG2-CD 4.21Å; T382-K386 WeakPolarHBondContact O-CB 3.11Å; T382-K386 WeakPolarHBondContact O-CG 3.06Å; T382-K386 PolarHBondContact O-N 2.93Å; T383-K386 PolarHBondContact O-N 3.49Å; V384-K386 VanDerWaalsContact C-N 3.32Å; V384-K386 PolarHBondContact O-N 3.35Å; K386-N389 PolarHBondContact O-N 3.42Å; K386-C390 WeakPolarHBondContact O-CB 3.29Å; K386-C390 PolarHBondContact O-N 2.87Å; K386-C390 PolarHBondContact O-SG 3.28Å; K386-A495 VanDerWaalsContact CE-O 3.22Å; K386-A495 WeakPolarHBondContact CE-O 3.36Å; K386-A495 PolarHBondContact NZ-O 3.27Å; K386-A498 WeakPolarHBondContact CE-O 3.31Å; K386-A498 HydrophobicContact CG-CB 4.43Å; K386-A498 PolarHBondContact NZ-O 3.06Å
387	I	94.5	Very high	92.6	Very high	84 Å²	84	39 Å²	39	43%	0.431	22%	0.222	S	C	.	.	H	α-helix	trans	-62.7	-47.4	-179.9	-70.6	170.9	0	0	0	111.1	L379 T383 V384 N389 G391	L379-I387 HydrophobicContact CD1-CD1 3.91Å; T383-I387 HydrophobicContact CG2-CD1 3.69Å; T383-I387 HydrophobicContact CG2-CG1 4.32Å; T383-I387 WeakPolarHBondContact O-CB 3.45Å; T383-I387 VanDerWaalsContact O-CG1 3.29Å; T383-I387 WeakPolarHBondContact O-CG1 3.48Å; T383-I387 PolarHBondContact O-N 3.47Å; V384-I387 PolarHBondContact O-N 3.22Å; I387-N389 PolarHBondContact O-N 3.12Å; I387-G391 VanDerWaalsContact O-CA 3.3Å; I387-G391 WeakPolarHBondContact O-CA 3.37Å; I387-G391 PolarHBondContact O-N 2.74Å
388	M	93.9	Very high	93	Very high	17 Å²	17	34.3 Å²	34.3	8%	0.084	20%	0.204	C	C	.	.	H	α-helix	trans	-64.8	-42.2	-178.6	-63.3	-60.6	150	0	0	111.7	I369 A370 L373 V384 G392	I369-M388 HydrophobicContact CG2-CE 3.76Å; A370-M388 HydrophobicContact CB-CG 4.4Å; L373-M388 HydrophobicContact CD1-CE 3.48Å; L373-M388 VanDerWaalsContact CD1-CE 3.48Å; V384-M388 HydrophobicContact CG1-CE 4.42Å; V384-M388 HydrophobicContact CG1-CG 4.08Å; V384-M388 WeakPolarHBondContact O-CB 3.32Å; V384-M388 WeakPolarHBondContact O-CG 3.24Å; V384-M388 PolarHBondContact O-N 2.89Å; M388-G392 PolarHBondContact O-N 3.35Å; M388-G392 VanDerWaalsContact O-N 3.12Å
389	N	92.9	Very high	93.2	Very high	0 Å²	0	30.4 Å²	30.4	0%	0	18%	0.184	C	C	.	.	H	α-helix	trans	-73.7	-53.5	179.5	-162.8	33.3	0	0	0	112.5	R385 K386 I387 G392 F393 A426 Y494	R385-N389 VanDerWaalsContact O-CB 3.25Å; R385-N389 WeakPolarHBondContact O-CB 3.38Å; R385-N389 PolarHBondContact O-N 3.36Å; R385-N389 VanDerWaalsContact O-N 3.09Å; K386-N389 PolarHBondContact O-N 3.42Å; I387-N389 PolarHBondContact O-N 3.12Å; N389-G392 PolarHBondContact O-N 2.97Å; N389-F393 WeakPolarHBondContact O-CB 3.22Å; N389-F393 PolarHBondContact O-N 3.15Å; N389-F393 WeakPolarHBondContact OD1-CE2 3.42Å; N389-A426 WeakPolarHBondContact OD1-CB 3.29Å; N389-Y494 HydrophobicContact CB-CD1 3.89Å; N389-Y494 HydrophobicContact CB-CE1 3.6Å; N389-Y494 WeakPolarHBondContact ND2-CD1 3.06Å; N389-Y494 WeakPolarHBondContact ND2-CD2 3.35Å; N389-Y494 VanDerWaalsContact ND2-CE1 3.26Å; N389-Y494 WeakPolarHBondContact ND2-CE1 3.45Å
390	C	92.7	Very high	93.3	Very high	27 Å²	27	27.8 Å²	27.8	18%	0.182	17%	0.17	C	C	.	.	H	α-helix	trans	-68.8	-36.6	-176.8	-59.6	0	0	0	0	111.9	K386 G394 V491	K386-C390 WeakPolarHBondContact O-CB 3.29Å; K386-C390 PolarHBondContact O-N 2.87Å; K386-C390 PolarHBondContact O-SG 3.28Å; C390-G394 VanDerWaalsContact O-CA 3.31Å; C390-G394 WeakPolarHBondContact O-CA 3.48Å; C390-G394 PolarHBondContact O-N 3.21Å; C390-V491 HydrophobicContact CB-CG1 3.81Å
391	G	92.1	Very high	93.4	Very high	42 Å²	42	26.6 Å²	26.6	43%	0.433	16%	0.158	S	C	.	.	H	α-helix	trans	-65.7	-47.7	173.5	0	0	0	0	0	111.8	I387 M395	I387-G391 VanDerWaalsContact O-CA 3.3Å; I387-G391 WeakPolarHBondContact O-CA 3.37Å; I387-G391 PolarHBondContact O-N 2.74Å; G391-M395 WeakPolarHBondContact O-CB 3.48Å; G391-M395 PolarHBondContact O-N 3.17Å
392	G	93	Very high	93.6	Very high	2 Å²	2	27.7 Å²	27.7	2%	0.021	17%	0.165	C	C	.	.	H	α-helix	trans	-62.3	-57.7	178.3	0	0	0	0	0	112.9	M388 N389 M395 E396 F422	M388-G392 PolarHBondContact O-N 3.35Å; M388-G392 VanDerWaalsContact O-N 3.12Å; N389-G392 PolarHBondContact O-N 2.97Å; G392-M395 PolarHBondContact O-N 3.48Å; G392-E396 WeakPolarHBondContact O-CB 3.33Å; G392-E396 PolarHBondContact O-N 3Å; G392-F422 VanDerWaalsContact CA-O 3.26Å; G392-F422 WeakPolarHBondContact CA-O 3.31Å
393	F	92.3	Very high	93.6	Very high	0 Å²	0	26.6 Å²	26.6	0%	0	16%	0.158	C	C	.	.	H	α-helix	trans	-70.3	-35.1	-178.9	-77	-2.7	0	0	0	113.8	A318 R322 N389 E396 A397 A426 F430 V491	A318-F393 HydrophobicContact CB-CE2 4.42Å; R322-F393 HydrophobicContact CB-CE1 4.33Å; R322-F393 HydrophobicContact CB-CE2 4.22Å; R322-F393 HydrophobicContact CB-CZ 3.57Å; R322-F393 HydrophobicContact CG-CE1 4.43Å; R322-F393 HydrophobicContact CG-CZ 4.01Å; N389-F393 WeakPolarHBondContact O-CB 3.22Å; N389-F393 PolarHBondContact O-N 3.15Å; N389-F393 WeakPolarHBondContact OD1-CE2 3.42Å; F393-E396 WeakPolarHBondContact CD1-OE2 3.33Å; F393-E396 PolarHBondContact O-N 3.35Å; F393-A397 WeakPolarHBondContact O-CB 3.31Å; F393-A397 PolarHBondContact O-N 2.92Å; F393-A426 HydrophobicContact CD1-CB 3.29Å; F393-A426 HydrophobicContact CE1-CB 3.05Å; F393-A426 HydrophobicContact CE2-CB 4.41Å; F393-A426 HydrophobicContact CG-CB 4.05Å; F393-A426 HydrophobicContact CZ-CB 3.63Å; F393-F430 HydrophobicContact CE1-CE1 4.5Å; F393-F430 HydrophobicContact CE2-CD1 4.26Å; F393-F430 HydrophobicContact CE2-CE1 4.4Å; F393-F430 AromaticContact CZ-CD1 3.88Å; F393-F430 HydrophobicContact CZ-CD1 3.88Å; F393-F430 AromaticContact CZ-CE1 3.66Å; F393-F430 HydrophobicContact CZ-CE1 3.66Å; F393-V491 HydrophobicContact CB-CG2 3.35Å; F393-V491 HydrophobicContact CD2-CG2 4.46Å; F393-V491 HydrophobicContact CG-CG2 4.44Å
394	G	93.5	Very high	93.5	Very high	15 Å²	15	24 Å²	24	16%	0.155	14%	0.143	C	C	.	.	H	α-helix	trans	-65.2	-41.5	176.5	0	0	0	0	0	111.5	C390 A397 T398	C390-G394 VanDerWaalsContact O-CA 3.31Å; C390-G394 WeakPolarHBondContact O-CA 3.48Å; C390-G394 PolarHBondContact O-N 3.21Å; G394-A397 PolarHBondContact O-N 2.95Å; G394-T398 PolarHBondContact O-N 3.42Å; G394-T398 VanDerWaalsContact O-N 3.17Å
395	M	94.7	Very high	93.5	Very high	82 Å²	82	29.4 Å²	29.4	40%	0.404	16%	0.164	S	C	.	.	H	α-helix	trans	-71.6	-39.3	175.7	-165.4	128.4	-68.5	0	0	112.1	G391 G392 A397 T398 L399 F422	G391-M395 WeakPolarHBondContact O-CB 3.48Å; G391-M395 PolarHBondContact O-N 3.17Å; G392-M395 PolarHBondContact O-N 3.48Å; M395-A397 VanDerWaalsContact C-N 3.31Å; M395-A397 PolarHBondContact O-N 2.97Å; M395-T398 PolarHBondContact O-N 3.09Å; M395-T398 PolarHBondContact O-OG1 3.24Å; M395-L399 HydrophobicContact CG-CD1 3.94Å; M395-L399 HydrophobicContact CG-CG 4.36Å; M395-L399 WeakPolarHBondContact O-CB 3.24Å; M395-L399 VanDerWaalsContact O-CG 3.23Å; M395-L399 WeakPolarHBondContact O-CG 3.35Å; M395-L399 PolarHBondContact O-N 3.2Å; M395-F422 HydrophobicContact CB-CB 4.15Å; M395-F422 HydrophobicContact CB-CD1 4.38Å; M395-F422 HydrophobicContact CB-CD2 4.48Å; M395-F422 HydrophobicContact CB-CG 4.1Å; M395-F422 HydrophobicContact CG-CB 4.26Å; M395-F422 HydrophobicContact CG-CD1 4.13Å; M395-F422 HydrophobicContact CG-CD2 3.68Å; M395-F422 HydrophobicContact CG-CE1 4.41Å; M395-F422 HydrophobicContact CG-CE2 3.97Å; M395-F422 HydrophobicContact CG-CG 3.76Å; M395-F422 HydrophobicContact CG-CZ 4.33Å; M395-F422 HydrophobicContact SD-CD1 4.26Å; M395-F422 HydrophobicContact SD-CD2 4.3Å; M395-F422 HydrophobicContact SD-CE1 3.99Å; M395-F422 HydrophobicContact SD-CE2 4.01Å; M395-F422 HydrophobicContact SD-CG 4.42Å; M395-F422 HydrophobicContact SD-CZ 3.86Å
396	E	94.2	Very high	93.3	Very high	1 Å²	1	29.7 Å²	29.7	1%	0.005	17%	0.166	C	C	.	.	H	α-helix	trans	-57.4	-44.5	172.1	177.8	176	-154.6	0	0	111.6	T325 G392 F393 L399 L400 A419 S423 H487	T325-E396 WeakPolarHBondContact CG2-OE1 3.36Å; G392-E396 WeakPolarHBondContact O-CB 3.33Å; G392-E396 PolarHBondContact O-N 3Å; F393-E396 WeakPolarHBondContact CD1-OE2 3.33Å; F393-E396 PolarHBondContact O-N 3.35Å; E396-L399 PolarHBondContact O-N 2.81Å; E396-L400 HydrophobicContact CG-CD1 4.01Å; E396-L400 HydrophobicContact CG-CG 4.35Å; E396-L400 WeakPolarHBondContact O-CB 3.43Å; E396-L400 WeakPolarHBondContact O-CG 3.34Å; E396-L400 PolarHBondContact O-N 3.04Å; E396-A419 HydrophobicContact CG-CB 4.4Å; E396-S423 VanDerWaalsContact OE1-CB 3.3Å; E396-S423 WeakPolarHBondContact OE1-CB 3.46Å; E396-S423 PolarHBondContact OE1-OG 3.41Å; E396-S423 VanDerWaalsContact OE1-OG 3.06Å; E396-S423 WeakPolarHBondContact OE2-CB 3.22Å; E396-S423 PolarHBondContact OE2-OG 3.37Å; E396-H487 IonicContact OE2-CD2 2.7Å
397	A	94.4	Very high	92.9	Very high	0 Å²	0	33.4 Å²	33.4	0%	0	18%	0.184	C	C	.	.	H	α-helix	trans	-62.1	-45.1	179	0	0	0	0	0	112.8	F393 G394 M395 L400 L401 A484 H487 Y488	F393-A397 WeakPolarHBondContact O-CB 3.31Å; F393-A397 PolarHBondContact O-N 2.92Å; G394-A397 PolarHBondContact O-N 2.95Å; M395-A397 VanDerWaalsContact C-N 3.31Å; M395-A397 PolarHBondContact O-N 2.97Å; A397-L400 PolarHBondContact O-N 2.93Å; A397-L401 PolarHBondContact O-N 3.18Å; A397-A484 HydrophobicContact CB-CB 4.5Å; A397-H487 HydrophobicContact CB-CB 3.64Å; A397-Y488 HydrophobicContact CB-CD1 4.15Å; A397-Y488 HydrophobicContact CB-CD2 4.29Å; A397-Y488 HydrophobicContact CB-CE1 3.83Å; A397-Y488 HydrophobicContact CB-CE2 3.99Å; A397-Y488 HydrophobicContact CB-CG 4.36Å
398	T	95.5	Very high	92.6	Very high	55 Å²	55	33.2 Å²	33.2	34%	0.337	19%	0.187	S	C	.	.	H	α-helix	trans	-62.4	-45	176.3	53.8	0	0	0	0	111	G394 M395 L401 V402 Y488	G394-T398 PolarHBondContact O-N 3.42Å; G394-T398 VanDerWaalsContact O-N 3.17Å; M395-T398 PolarHBondContact O-N 3.09Å; M395-T398 PolarHBondContact O-OG1 3.24Å; T398-L401 WeakPolarHBondContact O-CB 3.09Å; T398-L401 PolarHBondContact O-N 3.03Å; T398-V402 PolarHBondContact O-N 3.33Å; T398-Y488 WeakPolarHBondContact CA-OH 3.49Å; T398-Y488 HydrophobicContact CG2-CE1 4.4Å; T398-Y488 WeakPolarHBondContact CG2-OH 3.38Å; T398-Y488 PolarHBondContact N-OH 3.45Å
399	L	94.9	Very high	92.1	Very high	19 Å²	19	39.1 Å²	39.1	10%	0.099	21%	0.208	C	C	.	.	H	α-helix	trans	-68.2	-36.7	-178.8	-66.2	172.1	0	0	0	112.1	M395 E396 L401 V402 V403 F415 L418 A419 F422	M395-L399 HydrophobicContact CG-CD1 3.94Å; M395-L399 HydrophobicContact CG-CG 4.36Å; M395-L399 WeakPolarHBondContact O-CB 3.24Å; M395-L399 VanDerWaalsContact O-CG 3.23Å; M395-L399 WeakPolarHBondContact O-CG 3.35Å; M395-L399 PolarHBondContact O-N 3.2Å; E396-L399 PolarHBondContact O-N 2.81Å; L399-L401 VanDerWaalsContact C-N 3.32Å; L399-L401 PolarHBondContact O-N 3.46Å; L399-V402 WeakPolarHBondContact O-CB 3.37Å; L399-V402 PolarHBondContact O-N 3.45Å; L399-V402 VanDerWaalsContact O-N 3.14Å; L399-V403 WeakPolarHBondContact O-CG2 3.43Å; L399-V403 PolarHBondContact O-N 2.98Å; L399-F415 HydrophobicContact CD2-CD1 3.44Å; L399-F415 VanDerWaalsContact CD2-CD1 3.44Å; L399-F415 HydrophobicContact CD2-CE1 3.77Å; L399-L418 HydrophobicContact CD1-CB 3.93Å; L399-A419 HydrophobicContact CB-CB 3.7Å; L399-A419 HydrophobicContact CD1-CB 4.36Å; L399-F422 HydrophobicContact CD1-CD2 3.54Å; L399-F422 HydrophobicContact CD1-CE2 4.03Å
400	L	92.5	Very high	91.8	Very high	0 Å²	0	41.3 Å²	41.3	0%	0	23%	0.231	C	C	.	.	H	α-helix	trans	-63.5	-34.9	174	-76.3	176.4	0	0	0	112.7	T325 L329 E396 A397 V403 G404 A419 F480	T325-L400 HydrophobicContact CG2-CD1 3.82Å; L329-L400 HydrophobicContact CD2-CD2 4.16Å; E396-L400 HydrophobicContact CG-CD1 4.01Å; E396-L400 HydrophobicContact CG-CG 4.35Å; E396-L400 WeakPolarHBondContact O-CB 3.43Å; E396-L400 WeakPolarHBondContact O-CG 3.34Å; E396-L400 PolarHBondContact O-N 3.04Å; A397-L400 PolarHBondContact O-N 2.93Å; L400-V403 PolarHBondContact O-N 2.63Å; L400-G404 PolarHBondContact O-N 3.25Å; L400-A419 HydrophobicContact CD2-CB 4.34Å; L400-A419 HydrophobicContact CG-CB 4.32Å; L400-F480 HydrophobicContact CD2-CD1 4.25Å; L400-F480 HydrophobicContact CD2-CE1 4.16Å
401	L	94.2	Very high	91.7	Very high	41 Å²	41	42.5 Å²	42.5	22%	0.215	24%	0.237	C	C	.	.	H	α-helix	trans	-62.8	-44.3	171	-72	172.1	0	0	0	111.2	A397 T398 L399 V403 G404 Y405 L481 A484 Y488	A397-L401 PolarHBondContact O-N 3.18Å; T398-L401 WeakPolarHBondContact O-CB 3.09Å; T398-L401 PolarHBondContact O-N 3.03Å; L399-L401 VanDerWaalsContact C-N 3.32Å; L399-L401 PolarHBondContact O-N 3.46Å; L401-V403 VanDerWaalsContact C-N 3.27Å; L401-V403 PolarHBondContact O-N 3.06Å; L401-G404 PolarHBondContact O-N 3.11Å; L401-Y405 HydrophobicContact CD2-CE2 4.38Å; L401-Y405 VanDerWaalsContact O-CD2 3.27Å; L401-Y405 WeakPolarHBondContact O-CD2 3.3Å; L401-Y405 PolarHBondContact O-N 3.26Å; L401-L481 HydrophobicContact CD2-CD1 3.78Å; L401-A484 HydrophobicContact CD1-CB 3.99Å; L401-A484 HydrophobicContact CD2-CB 3.56Å; L401-A484 HydrophobicContact CG-CB 3.49Å; L401-A484 VanDerWaalsContact CG-CB 3.49Å; L401-Y488 HydrophobicContact CD1-CE2 4.09Å
402	V	94.3	Very high	91.5	Very high	60 Å²	60	40.5 Å²	40.5	36%	0.364	22%	0.217	S	C	.	.	H	α-helix	trans	-60.5	-39.4	176.4	179.5	0	0	0	0	111	T398 L399 S406 V411 F415	T398-V402 PolarHBondContact O-N 3.33Å; L399-V402 WeakPolarHBondContact O-CB 3.37Å; L399-V402 PolarHBondContact O-N 3.45Å; L399-V402 VanDerWaalsContact O-N 3.14Å; V402-S406 WeakPolarHBondContact O-CB 3.47Å; V402-S406 PolarHBondContact O-N 3.29Å; V402-V411 HydrophobicContact CG1-CG1 4.45Å; V402-F415 HydrophobicContact CB-CD1 3.84Å; V402-F415 HydrophobicContact CB-CE1 4.28Å; V402-F415 HydrophobicContact CB-CG 4.48Å; V402-F415 HydrophobicContact CG1-CD1 3.5Å; V402-F415 VanDerWaalsContact CG1-CD1 3.5Å; V402-F415 HydrophobicContact CG1-CD2 4.43Å; V402-F415 HydrophobicContact CG1-CE1 3.72Å; V402-F415 HydrophobicContact CG1-CG 3.9Å; V402-F415 HydrophobicContact CG1-CZ 4.26Å; V402-F415 HydrophobicContact CG2-CD1 4.38Å; V402-F415 HydrophobicContact CG2-CE1 4.43Å
403	V	91.8	Very high	91.3	Very high	0 Å²	0	42.1 Å²	42.1	0%	0	22%	0.224	C	C	.	.	H	α-helix	trans	-61.4	-50.2	173.8	175.1	0	0	0	0	110.8	Y336 L399 L400 L401 Y405 S406 F415 L416 F480	Y336-V403 HydrophobicContact CE1-CG1 4.08Å; Y336-V403 PolarHBondContact OH-O 3.06Å; Y336-V403 VanDerWaalsContact OH-O 3.08Å; L399-V403 WeakPolarHBondContact O-CG2 3.43Å; L399-V403 PolarHBondContact O-N 2.98Å; L400-V403 PolarHBondContact O-N 2.63Å; L401-V403 VanDerWaalsContact C-N 3.27Å; L401-V403 PolarHBondContact O-N 3.06Å; V403-Y405 VanDerWaalsContact C-N 3.3Å; V403-Y405 PolarHBondContact O-N 3.28Å; V403-S406 VanDerWaalsContact O-CB 3.31Å; V403-S406 WeakPolarHBondContact O-CB 3.21Å; V403-S406 PolarHBondContact O-N 3.37Å; V403-S406 PolarHBondContact O-OG 2.9Å; V403-F415 HydrophobicContact CG2-CB 3.73Å; V403-L416 HydrophobicContact CG1-CD1 4.48Å; V403-L416 HydrophobicContact CG2-CB 4Å; V403-F480 HydrophobicContact CG1-CE1 4.41Å; V403-F480 HydrophobicContact CG1-CZ 4.22Å
404	G	90.7	Very high	91.2	Very high	2 Å²	2	45.2 Å²	45.2	2%	0.021	25%	0.246	C	C	.	.	H	α-helix	trans	-57.7	-40.4	-179.7	0	0	0	0	0	113.5	L400 L401 Q477	L400-G404 PolarHBondContact O-N 3.25Å; L401-G404 PolarHBondContact O-N 3.11Å; G404-Q477 VanDerWaalsContact O-CG 3.32Å; G404-Q477 WeakPolarHBondContact O-CG 3.28Å
405	Y	92.6	Very high	91.1	Very high	113 Å²	113	47.7 Å²	47.7	44%	0.443	25%	0.253	S	S	.	.	T	Hydrogen-bonded Turn	trans	-90.9	7.1	178.4	-67.4	-73.9	0	0	0	114.2	L401 V403 H407 Q477	L401-Y405 HydrophobicContact CD2-CE2 4.38Å; L401-Y405 VanDerWaalsContact O-CD2 3.27Å; L401-Y405 WeakPolarHBondContact O-CD2 3.3Å; L401-Y405 PolarHBondContact O-N 3.26Å; V403-Y405 VanDerWaalsContact C-N 3.3Å; V403-Y405 PolarHBondContact O-N 3.28Å; Y405-H407 PolarHBondContact O-CD2 3.41Å; Y405-H407 PolarHBondContact O-NE2 2.96Å; Y405-Q477 HydrophobicContact CD1-CG 4.17Å; Y405-Q477 HydrophobicContact CE1-CB 4.29Å; Y405-Q477 HydrophobicContact CE1-CG 4.19Å
406	S	89.8	Confident	91	Very high	6 Å²	6	44 Å²	44	4%	0.042	23%	0.234	C	C	.	.			trans	-73.7	135.1	-178.6	67.8	0	0	0	0	112.2	V402 V403 A412 R473	V402-S406 WeakPolarHBondContact O-CB 3.47Å; V402-S406 PolarHBondContact O-N 3.29Å; V403-S406 VanDerWaalsContact O-CB 3.31Å; V403-S406 WeakPolarHBondContact O-CB 3.21Å; V403-S406 PolarHBondContact O-N 3.37Å; V403-S406 PolarHBondContact O-OG 2.9Å; S406-A412 VanDerWaalsContact OG-CB 3.22Å; S406-A412 WeakPolarHBondContact OG-CB 3.45Å; S406-R473 VanDerWaalsContact C-NH2 3.26Å; S406-R473 PolarHBondContact O-NH2 2.81Å
407	H	87.1	Confident	90.9	Very high	135 Å²	135	45.2 Å²	45.2	63%	0.625	24%	0.242	S	C	*	.			trans	-101.5	-10.9	177.3	-62.5	-100.3	0	0	0	115	Y405 R473	Y405-H407 PolarHBondContact O-CD2 3.41Å; Y405-H407 PolarHBondContact O-NE2 2.96Å; H407-R473 PolarHBondContact CE1-NH2 3.05Å; H407-R473 PolarHBondContact ND1-NH1 3.01Å; H407-R473 VanDerWaalsContact ND1-NH1 3.18Å; H407-R473 PolarHBondContact ND1-NH2 3.38Å
408	T	88	Confident	90.8	Very high	81 Å²	81	49.3 Å²	49.3	50%	0.497	26%	0.263	S	S	.	.	S	Bend	trans	-120.5	139.1	-178.9	59.4	0	0	0	0	110	G410 V411 A412	T408-G410 VanDerWaalsContact C-N 3.3Å; T408-G410 PolarHBondContact O-N 3.39Å; T408-V411 PolarHBondContact O-N 3.03Å; T408-V411 WeakPolarHBondContact OG1-CB 3.14Å; T408-V411 WeakPolarHBondContact OG1-CG2 3.48Å; T408-A412 PolarHBondContact O-N 3.23Å; T408-A412 VanDerWaalsContact O-N 3.12Å
409	R	83.8	Confident	90.7	Very high	141 Å²	141	46.7 Å²	46.7	53%	0.532	25%	0.247	S	C	.	.	H	α-helix	trans	-56.2	-44.2	-178.1	-63.2	176	179.4	153.1	-2.4	112.1	F341 V411 A412 I413	F341-R409 HydrophobicContact CB-CG 4.03Å; F341-R409 HydrophobicContact CD1-CB 4.47Å; F341-R409 HydrophobicContact CD1-CG 3.56Å; F341-R409 HydrophobicContact CE1-CG 4.29Å; F341-R409 HydrophobicContact CG-CG 3.99Å; F341-R409 PolarHBondContact O-NE 2.7Å; F341-R409 VanDerWaalsContact O-NE 3.17Å; F341-R409 PolarHBondContact O-NH2 3Å; R409-V411 VanDerWaalsContact C-N 3.33Å; R409-V411 PolarHBondContact O-N 3.2Å; R409-A412 PolarHBondContact O-N 3.43Å; R409-I413 WeakPolarHBondContact O-CG1 3.3Å; R409-I413 PolarHBondContact O-N 2.9Å; R409-I413 VanDerWaalsContact O-N 3.13Å
410	G	85.8	Confident	90.5	Very high	46 Å²	46	46.1 Å²	46.1	47%	0.474	25%	0.245	S	C	.	.	H	α-helix	trans	-62.8	-38.6	-178.8	0	0	0	0	0	113	T408 S414	T408-G410 VanDerWaalsContact C-N 3.3Å; T408-G410 PolarHBondContact O-N 3.39Å; G410-S414 VanDerWaalsContact O-CB 3.28Å; G410-S414 WeakPolarHBondContact O-CB 3.31Å; G410-S414 PolarHBondContact O-N 3.12Å; G410-S414 PolarHBondContact O-OG 3.22Å
411	V	90	Very high	90.6	Very high	52 Å²	52	46.5 Å²	46.5	32%	0.315	25%	0.248	S	C	.	.	H	α-helix	trans	-69	-48.3	177.3	172.1	0	0	0	0	110.2	V402 T408 R409 I413 S414 F415	V402-V411 HydrophobicContact CG1-CG1 4.45Å; T408-V411 PolarHBondContact O-N 3.03Å; T408-V411 WeakPolarHBondContact OG1-CB 3.14Å; T408-V411 WeakPolarHBondContact OG1-CG2 3.48Å; R409-V411 VanDerWaalsContact C-N 3.33Å; R409-V411 PolarHBondContact O-N 3.2Å; V411-I413 VanDerWaalsContact C-N 3.32Å; V411-I413 PolarHBondContact O-N 3.39Å; V411-S414 PolarHBondContact O-N 2.83Å; V411-F415 HydrophobicContact CG1-CD2 3.75Å; V411-F415 HydrophobicContact CG1-CE2 4.01Å; V411-F415 HydrophobicContact CG1-CG 4.49Å; V411-F415 WeakPolarHBondContact O-CB 3.36Å; V411-F415 WeakPolarHBondContact O-CD2 3.32Å; V411-F415 PolarHBondContact O-N 3Å
412	A	88.6	Confident	90.5	Very high	0 Å²	0	48 Å²	48	0%	0	25%	0.253	C	S	.	.	H	α-helix	trans	-52.7	-49.8	179.5	0	0	0	0	0	112	F337 F341 S406 T408 R409 L416	F337-A412 HydrophobicContact CE1-CB 3.95Å; F341-A412 HydrophobicContact CE2-CB 3.72Å; F341-A412 HydrophobicContact CZ-CB 3.72Å; S406-A412 VanDerWaalsContact OG-CB 3.22Å; S406-A412 WeakPolarHBondContact OG-CB 3.45Å; T408-A412 PolarHBondContact O-N 3.23Å; T408-A412 VanDerWaalsContact O-N 3.12Å; R409-A412 PolarHBondContact O-N 3.43Å; A412-L416 WeakPolarHBondContact O-CB 3.31Å; A412-L416 PolarHBondContact O-N 2.97Å
413	I	87.8	Confident	90.4	Very high	35 Å²	35	45.1 Å²	45.1	18%	0.179	24%	0.236	C	C	.	.	H	α-helix	trans	-67.3	-49.7	-178.8	-66.1	167.1	0	0	0	111.1	F337 L351 R409 V411 F415 L416 V417	F337-I413 HydrophobicContact CD1-CG1 4.43Å; F337-I413 HydrophobicContact CE1-CD1 4.44Å; F337-I413 HydrophobicContact CE1-CG1 3.56Å; F337-I413 HydrophobicContact CZ-CG1 3.71Å; L351-I413 HydrophobicContact CD1-CD1 4.23Å; L351-I413 HydrophobicContact CD1-CG2 3.72Å; L351-I413 HydrophobicContact CD2-CD1 3.51Å; L351-I413 HydrophobicContact CD2-CG1 3.91Å; L351-I413 HydrophobicContact CG-CD1 4.43Å; L351-I413 HydrophobicContact CG-CG2 4.43Å; R409-I413 WeakPolarHBondContact O-CG1 3.3Å; R409-I413 PolarHBondContact O-N 2.9Å; R409-I413 VanDerWaalsContact O-N 3.13Å; V411-I413 VanDerWaalsContact C-N 3.32Å; V411-I413 PolarHBondContact O-N 3.39Å; I413-F415 VanDerWaalsContact C-N 3.33Å; I413-F415 PolarHBondContact O-N 3.29Å; I413-L416 PolarHBondContact O-N 3.19Å; I413-V417 WeakPolarHBondContact O-CG2 3.36Å; I413-V417 PolarHBondContact O-N 3.13Å
414	S	90.6	Very high	90.3	Very high	66 Å²	66	45.1 Å²	45.1	46%	0.462	24%	0.236	S	C	.	.	H	α-helix	trans	-62.2	-43.9	-175.2	-55.7	0	0	0	0	111	G410 V411 V417 L418	G410-S414 VanDerWaalsContact O-CB 3.28Å; G410-S414 WeakPolarHBondContact O-CB 3.31Å; G410-S414 PolarHBondContact O-N 3.12Å; G410-S414 PolarHBondContact O-OG 3.22Å; V411-S414 PolarHBondContact O-N 2.83Å; S414-V417 PolarHBondContact O-N 3.42Å; S414-L418 WeakPolarHBondContact O-CG 3.46Å; S414-L418 PolarHBondContact O-N 3.48Å
415	F	92.9	Very high	90.4	Very high	67 Å²	67	47.1 Å²	47.1	29%	0.294	24%	0.244	S	C	.	.	H	α-helix	trans	-71.9	-32.2	178.8	-81.6	-104.9	0	0	0	112.6	L399 V402 V403 V411 I413 L418 A419	L399-F415 HydrophobicContact CD2-CD1 3.44Å; L399-F415 VanDerWaalsContact CD2-CD1 3.44Å; L399-F415 HydrophobicContact CD2-CE1 3.77Å; V402-F415 HydrophobicContact CB-CD1 3.84Å; V402-F415 HydrophobicContact CB-CE1 4.28Å; V402-F415 HydrophobicContact CB-CG 4.48Å; V402-F415 HydrophobicContact CG1-CD1 3.5Å; V402-F415 VanDerWaalsContact CG1-CD1 3.5Å; V402-F415 HydrophobicContact CG1-CD2 4.43Å; V402-F415 HydrophobicContact CG1-CE1 3.72Å; V402-F415 HydrophobicContact CG1-CG 3.9Å; V402-F415 HydrophobicContact CG1-CZ 4.26Å; V402-F415 HydrophobicContact CG2-CD1 4.38Å; V402-F415 HydrophobicContact CG2-CE1 4.43Å; V403-F415 HydrophobicContact CG2-CB 3.73Å; V411-F415 HydrophobicContact CG1-CD2 3.75Å; V411-F415 HydrophobicContact CG1-CE2 4.01Å; V411-F415 HydrophobicContact CG1-CG 4.49Å; V411-F415 WeakPolarHBondContact O-CB 3.36Å; V411-F415 WeakPolarHBondContact O-CD2 3.32Å; V411-F415 PolarHBondContact O-N 3Å; I413-F415 VanDerWaalsContact C-N 3.33Å; I413-F415 PolarHBondContact O-N 3.29Å; F415-L418 PolarHBondContact O-N 2.94Å; F415-A419 VanDerWaalsContact O-CB 3.31Å; F415-A419 WeakPolarHBondContact O-CB 3.49Å; F415-A419 PolarHBondContact O-N 3.48Å
416	L	91	Very high	90.4	Very high	3 Å²	3	41.8 Å²	41.8	2%	0.016	22%	0.223	C	C	.	.	H	α-helix	trans	-65.4	-43	173.7	-173.4	151.9	0	0	0	111.3	L329 Q333 F337 P355 V403 A412 I413 L418 A419 V420	L329-L416 HydrophobicContact CD2-CD1 4.23Å; Q333-L416 HydrophobicContact CG-CD1 4.23Å; F337-L416 HydrophobicContact CE2-CD1 3.92Å; F337-L416 HydrophobicContact CZ-CD1 4.04Å; P355-L416 HydrophobicContact CB-CD2 3.98Å; P355-L416 HydrophobicContact CG-CD2 3.36Å; V403-L416 HydrophobicContact CG1-CD1 4.48Å; V403-L416 HydrophobicContact CG2-CB 4Å; A412-L416 WeakPolarHBondContact O-CB 3.31Å; A412-L416 PolarHBondContact O-N 2.97Å; I413-L416 PolarHBondContact O-N 3.19Å; L416-L418 VanDerWaalsContact C-N 3.34Å; L416-L418 PolarHBondContact O-N 2.86Å; L416-A419 PolarHBondContact O-N 3.07Å; L416-V420 HydrophobicContact CD2-CG2 4.41Å; L416-V420 WeakPolarHBondContact O-CG2 3.31Å; L416-V420 PolarHBondContact O-N 3.43Å
417	V	91.9	Very high	90.4	Very high	28 Å²	28	41.7 Å²	41.7	17%	0.17	22%	0.222	C	C	.	.	H	α-helix	trans	-62.6	-42.6	175.4	174.3	0	0	0	0	110.9	V354 P355 V358 I413 S414 G421	V354-V417 HydrophobicContact CB-CG2 4.4Å; V354-V417 HydrophobicContact CG1-CG1 4.16Å; V354-V417 HydrophobicContact CG1-CG2 3.81Å; P355-V417 HydrophobicContact CG-CG2 4.19Å; V358-V417 HydrophobicContact CB-CG1 4.34Å; V358-V417 HydrophobicContact CG2-CG1 3.69Å; I413-V417 WeakPolarHBondContact O-CG2 3.36Å; I413-V417 PolarHBondContact O-N 3.13Å; S414-V417 PolarHBondContact O-N 3.42Å; V417-G421 PolarHBondContact O-N 2.89Å
418	L	93.7	Very high	90.5	Very high	85 Å²	85	35.3 Å²	35.3	45%	0.445	19%	0.193	S	C	.	.	H	α-helix	trans	-63.6	-43.4	174.9	-70.3	172.8	0	0	0	112	L399 S414 F415 L416 V420 G421 F422	L399-L418 HydrophobicContact CD1-CB 3.93Å; S414-L418 WeakPolarHBondContact O-CG 3.46Å; S414-L418 PolarHBondContact O-N 3.48Å; F415-L418 PolarHBondContact O-N 2.94Å; L416-L418 VanDerWaalsContact C-N 3.34Å; L416-L418 PolarHBondContact O-N 2.86Å; L418-V420 PolarHBondContact O-N 3.22Å; L418-G421 PolarHBondContact O-N 3.23Å; L418-F422 VanDerWaalsContact O-CD2 3.22Å; L418-F422 WeakPolarHBondContact O-CD2 3.3Å; L418-F422 PolarHBondContact O-N 3.47Å
419	A	93.1	Very high	90.6	Very high	0 Å²	0	31.4 Å²	31.4	0%	0	17%	0.169	C	C	.	.	H	α-helix	trans	-57.7	-49.7	179.1	0	0	0	0	0	111.3	E396 L399 L400 F415 L416 G421 F422 S423	E396-A419 HydrophobicContact CG-CB 4.4Å; L399-A419 HydrophobicContact CB-CB 3.7Å; L399-A419 HydrophobicContact CD1-CB 4.36Å; L400-A419 HydrophobicContact CD2-CB 4.34Å; L400-A419 HydrophobicContact CG-CB 4.32Å; F415-A419 VanDerWaalsContact O-CB 3.31Å; F415-A419 WeakPolarHBondContact O-CB 3.49Å; F415-A419 PolarHBondContact O-N 3.48Å; L416-A419 PolarHBondContact O-N 3.07Å; A419-G421 VanDerWaalsContact C-N 3.33Å; A419-G421 PolarHBondContact O-N 2.92Å; A419-F422 PolarHBondContact O-N 2.92Å; A419-S423 PolarHBondContact O-N 3.4Å
420	V	91.4	Very high	91	Very high	8 Å²	8	24.8 Å²	24.8	5%	0.048	14%	0.144	C	C	.	.	H	α-helix	trans	-66.7	-35.4	177.8	176.4	0	0	0	0	111.9	L329 P355 M359 L416 L418 S423 G424	L329-V420 HydrophobicContact CD1-CG2 3.42Å; L329-V420 VanDerWaalsContact CD1-CG2 3.42Å; P355-V420 HydrophobicContact CB-CB 3.8Å; P355-V420 HydrophobicContact CB-CG1 3.8Å; P355-V420 HydrophobicContact CB-CG2 3.77Å; P355-V420 VanDerWaalsContact O-CG1 3.24Å; P355-V420 WeakPolarHBondContact O-CG1 3.27Å; M359-V420 HydrophobicContact CB-CG1 3.95Å; M359-V420 HydrophobicContact CG-CG1 4.44Å; M359-V420 HydrophobicContact SD-CG1 4.34Å; L416-V420 HydrophobicContact CD2-CG2 4.41Å; L416-V420 WeakPolarHBondContact O-CG2 3.31Å; L416-V420 PolarHBondContact O-N 3.43Å; L418-V420 PolarHBondContact O-N 3.22Å; V420-S423 WeakPolarHBondContact O-CB 3.45Å; V420-S423 PolarHBondContact O-N 2.89Å; V420-G424 PolarHBondContact O-N 2.67Å
421	G	92.7	Very high	91.3	Very high	7 Å²	7	23.1 Å²	23.1	7%	0.072	12%	0.124	C	C	.	.	H	α-helix	trans	-58.9	-51.4	172.8	0	0	0	0	0	112.1	I362 V417 L418 A419 S423 G424	I362-G421 VanDerWaalsContact CG2-O 3.26Å; I362-G421 WeakPolarHBondContact CG2-O 3.44Å; V417-G421 PolarHBondContact O-N 2.89Å; L418-G421 PolarHBondContact O-N 3.23Å; A419-G421 VanDerWaalsContact C-N 3.33Å; A419-G421 PolarHBondContact O-N 2.92Å; G421-S423 VanDerWaalsContact C-N 3.33Å; G421-S423 PolarHBondContact O-N 2.89Å; G421-G424 PolarHBondContact O-N 3.05Å
422	F	93.5	Very high	91.4	Very high	72 Å²	72	20.7 Å²	20.7	32%	0.316	11%	0.109	S	C	.	.	H	α-helix	trans	-65.2	-34.3	177.7	-77.6	-69.1	0	0	0	113.1	G392 M395 L399 L418 A419 G424 F425	G392-F422 VanDerWaalsContact CA-O 3.26Å; G392-F422 WeakPolarHBondContact CA-O 3.31Å; M395-F422 HydrophobicContact CB-CB 4.15Å; M395-F422 HydrophobicContact CB-CD1 4.38Å; M395-F422 HydrophobicContact CB-CD2 4.48Å; M395-F422 HydrophobicContact CB-CG 4.1Å; M395-F422 HydrophobicContact CG-CB 4.26Å; M395-F422 HydrophobicContact CG-CD1 4.13Å; M395-F422 HydrophobicContact CG-CD2 3.68Å; M395-F422 HydrophobicContact CG-CE1 4.41Å; M395-F422 HydrophobicContact CG-CE2 3.97Å; M395-F422 HydrophobicContact CG-CG 3.76Å; M395-F422 HydrophobicContact CG-CZ 4.33Å; M395-F422 HydrophobicContact SD-CD1 4.26Å; M395-F422 HydrophobicContact SD-CD2 4.3Å; M395-F422 HydrophobicContact SD-CE1 3.99Å; M395-F422 HydrophobicContact SD-CE2 4.01Å; M395-F422 HydrophobicContact SD-CG 4.42Å; M395-F422 HydrophobicContact SD-CZ 3.86Å; L399-F422 HydrophobicContact CD1-CD2 3.54Å; L399-F422 HydrophobicContact CD1-CE2 4.03Å; L418-F422 VanDerWaalsContact O-CD2 3.22Å; L418-F422 WeakPolarHBondContact O-CD2 3.3Å; L418-F422 PolarHBondContact O-N 3.47Å; A419-F422 PolarHBondContact O-N 2.92Å; F422-G424 PolarHBondContact O-N 2.89Å; F422-F425 HydrophobicContact CD1-CD2 4Å; F422-F425 AromaticContact CD1-CE2 3.95Å; F422-F425 HydrophobicContact CD1-CE2 3.95Å; F422-F425 HydrophobicContact CE1-CE2 4.34Å; F422-F425 PolarHBondContact O-N 3.31Å; F422-F425 VanDerWaalsContact O-N 3.11Å
423	S	91.1	Very high	91.6	Very high	0 Å²	0	20.7 Å²	20.7	0%	0	11%	0.109	C	C	.	.	H	α-helix	trans	-55.2	-31.3	170.6	-161.2	0	0	0	0	112.7	E396 A419 V420 G421 F425 A426	E396-S423 VanDerWaalsContact OE1-CB 3.3Å; E396-S423 WeakPolarHBondContact OE1-CB 3.46Å; E396-S423 PolarHBondContact OE1-OG 3.41Å; E396-S423 VanDerWaalsContact OE1-OG 3.06Å; E396-S423 WeakPolarHBondContact OE2-CB 3.22Å; E396-S423 PolarHBondContact OE2-OG 3.37Å; A419-S423 PolarHBondContact O-N 3.4Å; V420-S423 WeakPolarHBondContact O-CB 3.45Å; V420-S423 PolarHBondContact O-N 2.89Å; G421-S423 VanDerWaalsContact C-N 3.33Å; G421-S423 PolarHBondContact O-N 2.89Å; S423-F425 VanDerWaalsContact C-N 3.26Å; S423-F425 PolarHBondContact O-N 3.04Å; S423-A426 WeakPolarHBondContact O-CB 3.28Å; S423-A426 PolarHBondContact O-N 3.19Å
424	G	90.9	Very high	91.9	Very high	0 Å²	0	19.1 Å²	19.1	0%	0	10%	0.101	C	C	.	.	H	α-helix	trans	-56.4	-36.4	176.5	0	0	0	0	0	113.8	V420 G421 F422 A426 I427	V420-G424 PolarHBondContact O-N 2.67Å; G421-G424 PolarHBondContact O-N 3.05Å; F422-G424 PolarHBondContact O-N 2.89Å; G424-A426 VanDerWaalsContact C-N 3.27Å; G424-A426 PolarHBondContact O-N 3.02Å; G424-I427 PolarHBondContact O-N 3.45Å
425	F	92.9	Very high	91.8	Very high	45 Å²	45	16 Å²	16	20%	0.197	8%	0.079	C	C	.	.	H	α-helix	trans	-65.9	-29.5	177.2	-66.3	-66.5	0	0	0	112.7	I362 I369 F422 S423 I427 S428 G429	I362-F425 HydrophobicContact CG2-CD1 4.12Å; I362-F425 HydrophobicContact CG2-CD2 4.03Å; I362-F425 HydrophobicContact CG2-CE1 3.83Å; I362-F425 HydrophobicContact CG2-CE2 3.74Å; I362-F425 HydrophobicContact CG2-CG 4.21Å; I362-F425 HydrophobicContact CG2-CZ 3.62Å; I369-F425 HydrophobicContact CD1-CE1 4.14Å; F422-F425 HydrophobicContact CD1-CD2 4Å; F422-F425 AromaticContact CD1-CE2 3.95Å; F422-F425 HydrophobicContact CD1-CE2 3.95Å; F422-F425 HydrophobicContact CE1-CE2 4.34Å; F422-F425 PolarHBondContact O-N 3.31Å; F422-F425 VanDerWaalsContact O-N 3.11Å; S423-F425 VanDerWaalsContact C-N 3.26Å; S423-F425 PolarHBondContact O-N 3.04Å; F425-I427 PolarHBondContact O-N 3.05Å; F425-S428 PolarHBondContact O-N 3.11Å; F425-S428 PolarHBondContact O-OG 3.19Å; F425-G429 PolarHBondContact O-N 2.95Å
426	A	91.1	Very high	91.7	Very high	0 Å²	0	13.3 Å²	13.3	0%	0	7%	0.068	C	C	.	.	H	α-helix	trans	-67.3	-25	179.9	0	0	0	0	0	113	N389 F393 S423 G424 S428 G429 F430	N389-A426 WeakPolarHBondContact OD1-CB 3.29Å; F393-A426 HydrophobicContact CD1-CB 3.29Å; F393-A426 HydrophobicContact CE1-CB 3.05Å; F393-A426 HydrophobicContact CE2-CB 4.41Å; F393-A426 HydrophobicContact CG-CB 4.05Å; F393-A426 HydrophobicContact CZ-CB 3.63Å; S423-A426 WeakPolarHBondContact O-CB 3.28Å; S423-A426 PolarHBondContact O-N 3.19Å; G424-A426 VanDerWaalsContact C-N 3.27Å; G424-A426 PolarHBondContact O-N 3.02Å; A426-S428 VanDerWaalsContact C-N 3.31Å; A426-S428 PolarHBondContact O-N 3.25Å; A426-G429 CarbonylContact O-C 3.44Å; A426-G429 VanDerWaalsContact O-CA 3.31Å; A426-G429 WeakPolarHBondContact O-CA 3.41Å; A426-G429 PolarHBondContact O-N 3.13Å; A426-F430 HydrophobicContact CB-CD1 4.5Å; A426-F430 WeakPolarHBondContact O-CD1 3.2Å; A426-F430 PolarHBondContact O-N 3.45Å
427	I	90.8	Very high	91.7	Very high	5 Å²	5	13.2 Å²	13.2	3%	0.026	7%	0.067	C	C	.	.	I	π-helix	trans	-63.3	-37	174.9	-56.1	-60.5	0	0	0	111.3	Y223 M359 V363 G424 F425 G429 F430 N431	Y223-I427 WeakPolarHBondContact OH-CD1 3.24Å; M359-I427 HydrophobicContact CE-CD1 4.1Å; M359-I427 HydrophobicContact CE-CG1 3.7Å; V363-I427 HydrophobicContact CG1-CB 4.21Å; V363-I427 HydrophobicContact CG1-CG2 3.93Å; V363-I427 HydrophobicContact CG2-CB 4.15Å; V363-I427 HydrophobicContact CG2-CG1 3.92Å; G424-I427 PolarHBondContact O-N 3.45Å; F425-I427 PolarHBondContact O-N 3.05Å; I427-G429 PolarHBondContact O-N 3.27Å; I427-F430 HydrophobicContact CD1-CE1 4.16Å; I427-F430 HydrophobicContact CD1-CZ 4.28Å; I427-N431 HydrophobicContact CG2-CB 4.18Å; I427-N431 WeakPolarHBondContact O-CB 3.39Å
428	S	88.3	Confident	91.5	Very high	0 Å²	0	11.9 Å²	11.9	0%	0	6%	0.059	C	C	.	.	I	π-helix	trans	-76.5	-11.8	172.5	69.2	0	0	0	0	112.9	G366 R385 F425 A426	G366-S428 VanDerWaalsContact C-OG 3.31Å; G366-S428 WeakPolarHBondContact O-CB 3.23Å; G366-S428 PolarHBondContact O-OG 3.3Å; G366-S428 VanDerWaalsContact O-OG 3.04Å; R385-S428 PolarHBondContact NH1-O 3.46Å; F425-S428 PolarHBondContact O-N 3.11Å; F425-S428 PolarHBondContact O-OG 3.19Å; A426-S428 VanDerWaalsContact C-N 3.31Å; A426-S428 PolarHBondContact O-N 3.25Å
429	G	90.4	Very high	91.1	Very high	0 Å²	0	8.6 Å²	8.6	0%	0	4%	0.043	C	C	.	.	I	π-helix	trans	-81.4	-86	172.7	0	0	0	0	0	112.7	R385 F425 A426 I427	R385-G429 WeakPolarHBondContact CD-O 3.39Å; F425-G429 PolarHBondContact O-N 2.95Å; A426-G429 CarbonylContact O-C 3.44Å; A426-G429 VanDerWaalsContact O-CA 3.31Å; A426-G429 WeakPolarHBondContact O-CA 3.41Å; A426-G429 PolarHBondContact O-N 3.13Å; I427-G429 PolarHBondContact O-N 3.27Å
430	F	92.2	Very high	90.6	Very high	2 Å²	2	9.5 Å²	9.5	1%	0.009	5%	0.047	C	C	.	.	I	π-helix	trans	-76.7	-34	-169.1	79.2	-86.7	0	0	0	113.6	A318 N319 R322 F393 A426 I427 V432 N433 Y494	A318-F430 HydrophobicContact CB-CB 3.97Å; A318-F430 HydrophobicContact CB-CD2 4.44Å; A318-F430 HydrophobicContact CB-CG 4.09Å; N319-F430 HydrophobicContact CB-CD2 4.29Å; N319-F430 HydrophobicContact CB-CE2 3.9Å; N319-F430 WeakPolarHBondContact OD1-CE2 3.48Å; R322-F430 HydrophobicContact CB-CE1 4.26Å; R322-F430 HydrophobicContact CB-CZ 4.07Å; R322-F430 HydrophobicContact CG-CE1 4.1Å; R322-F430 HydrophobicContact CG-CZ 3.88Å; F393-F430 HydrophobicContact CE1-CE1 4.5Å; F393-F430 HydrophobicContact CE2-CD1 4.26Å; F393-F430 HydrophobicContact CE2-CE1 4.4Å; F393-F430 AromaticContact CZ-CD1 3.88Å; F393-F430 HydrophobicContact CZ-CD1 3.88Å; F393-F430 AromaticContact CZ-CE1 3.66Å; F393-F430 HydrophobicContact CZ-CE1 3.66Å; A426-F430 HydrophobicContact CB-CD1 4.5Å; A426-F430 WeakPolarHBondContact O-CD1 3.2Å; A426-F430 PolarHBondContact O-N 3.45Å; I427-F430 HydrophobicContact CD1-CE1 4.16Å; I427-F430 HydrophobicContact CD1-CZ 4.28Å; F430-V432 VanDerWaalsContact C-N 3.34Å; F430-V432 PolarHBondContact O-N 3.26Å; F430-N433 VanDerWaalsContact O-CB 3.28Å; F430-N433 WeakPolarHBondContact O-CB 3.26Å; F430-N433 PolarHBondContact O-N 3.26Å; F430-N433 VanDerWaalsContact O-N 3.13Å; F430-Y494 WeakPolarHBondContact CA-OH 3.33Å; F430-Y494 HydrophobicContact CB-CE2 3.86Å
431	N	91.6	Very high	90.4	Very high	11 Å²	11	9.8 Å²	9.8	6%	0.059	5%	0.047	C	C	.	.	I	π-helix	trans	-67.9	-37.8	-170.1	-158.1	46.4	0	0	0	111.4	H199 F219 I427 N433 H434 M446	H199-N431 PolarHBondContact NE2-O 3.43Å; F219-N431 WeakPolarHBondContact CD2-ND2 3.21Å; F219-N431 WeakPolarHBondContact CE2-ND2 3.4Å; I427-N431 HydrophobicContact CG2-CB 4.18Å; I427-N431 WeakPolarHBondContact O-CB 3.39Å; N431-N433 VanDerWaalsContact C-N 3.32Å; N431-H434 PolarHBondContact O-ND1 3.25Å; N431-M446 WeakPolarHBondContact OD1-CE 2.88Å
432	V	92.1	Very high	90.2	Very high	0 Å²	0	9.4 Å²	9.4	0%	0	4%	0.043	C	C	.	.	H	α-helix	trans	-75.9	-22	176.9	-170.1	0	0	0	0	112	R211 A215 R385 F430 H434 L435	R211-V432 HydrophobicContact CB-CG1 4.18Å; A215-V432 HydrophobicContact CB-CG2 4.12Å; R385-V432 VanDerWaalsContact NH2-CG1 3.28Å; F430-V432 VanDerWaalsContact C-N 3.34Å; F430-V432 PolarHBondContact O-N 3.26Å; V432-H434 PolarHBondContact O-N 3.45Å; V432-H434 VanDerWaalsContact O-N 3.1Å; V432-L435 HydrophobicContact CG1-CD1 4.41Å; V432-L435 WeakPolarHBondContact O-CB 3.4Å; V432-L435 PolarHBondContact O-N 3.12Å
433	N	94.3	Very high	90.1	Very high	0 Å²	0	6.2 Å²	6.2	0%	0	3%	0.03	C	C	.	.	H	α-helix	trans	-62.5	-24.1	-172.5	-161.4	11.7	0	0	0	113.6	I315 F430 N431 L435 D436 I437 Y494 S499	I315-N433 HydrophobicContact CD1-CB 3.78Å; I315-N433 HydrophobicContact CG1-CB 4.26Å; F430-N433 VanDerWaalsContact O-CB 3.28Å; F430-N433 WeakPolarHBondContact O-CB 3.26Å; F430-N433 PolarHBondContact O-N 3.26Å; F430-N433 VanDerWaalsContact O-N 3.13Å; N431-N433 VanDerWaalsContact C-N 3.32Å; N433-L435 PolarHBondContact O-N 3.28Å; N433-D436 PolarHBondContact O-N 3.34Å; N433-D436 VanDerWaalsContact O-N 3.1Å; N433-I437 WeakPolarHBondContact O-CG1 3.04Å; N433-I437 PolarHBondContact O-N 2.95Å; N433-I437 VanDerWaalsContact O-N 3.07Å; N433-Y494 PolarHBondContact ND2-OH 3.13Å; N433-S499 PolarHBondContact ND2-O 3.2Å; N433-S499 VanDerWaalsContact ND2-O 3.08Å; N433-S499 PolarHBondContact OD1-O 3.47Å
434	H	92.7	Very high	90.2	Very high	3 Å²	3	6.2 Å²	6.2	1%	0.014	3%	0.03	C	C	.	.	H	α-helix	trans	-55.2	-39.1	171.9	-57.1	89.2	0	0	0	112.6	I315 N431 V432 A438 M446 S449	I315-H434 WeakPolarHBondContact CG2-CE1 3.45Å; I315-H434 WeakPolarHBondContact CG2-NE2 3.48Å; N431-H434 PolarHBondContact O-ND1 3.25Å; V432-H434 PolarHBondContact O-N 3.45Å; V432-H434 VanDerWaalsContact O-N 3.1Å; H434-A438 PolarHBondContact O-N 3.34Å; H434-M446 WeakPolarHBondContact CE1-CE 3.43Å; H434-M446 WeakPolarHBondContact ND1-CE 3.46Å; H434-S449 VanDerWaalsContact NE2-CB 3.27Å; H434-S449 WeakPolarHBondContact NE2-CB 3.13Å; H434-S449 PolarHBondContact NE2-OG 2.92Å
435	L	89.1	Confident	90.3	Very high	0 Å²	0	6.5 Å²	6.5	0%	0	3%	0.031	C	C	.	.	H	α-helix	trans	-74.4	-27.3	179.7	-67.5	160.9	0	0	0	112.1	W202 R211 V432 N433 P439 A442	W202-L435 HydrophobicContact CB-CD1 3.97Å; W202-L435 HydrophobicContact CB-CD2 4.21Å; R211-L435 PolarHBondContact NH1-O 2.97Å; V432-L435 HydrophobicContact CG1-CD1 4.41Å; V432-L435 WeakPolarHBondContact O-CB 3.4Å; V432-L435 PolarHBondContact O-N 3.12Å; N433-L435 PolarHBondContact O-N 3.28Å; L435-P439 WeakPolarHBondContact O-CD 3.49Å; L435-P439 VanDerWaalsContact O-CG 3.22Å; L435-P439 WeakPolarHBondContact O-CG 3.24Å; L435-A442 HydrophobicContact CD2-CB 3.77Å; L435-A442 HydrophobicContact CG-CB 4.4Å
436	D	90.5	Very high	90.3	Very high	10 Å²	10	4.4 Å²	4.4	5%	0.053	2%	0.022	C	C	.	.	H	α-helix	trans	-80	-42.6	-178.1	-64.2	-31.6	0	0	0	111.1	R211 T381 R385 N433	R211-D436 IonicContact NH1-OD1 3.36Å; R211-D436 PolarHBondContact NH1-OD1 3.42Å; T381-D436 HydrophobicContact CG2-CB 4.4Å; R385-D436 IonicContact CZ-OD2 2.96Å; R385-D436 IonicContact NE-OD2 3.97Å; R385-D436 PolarHBondContact NE-OD2 2.93Å; R385-D436 IonicContact NH2-OD1 2.69Å; R385-D436 IonicContact NH2-OD2 2.86Å; R385-D436 PolarHBondContact NH2-OD2 3.34Å; N433-D436 PolarHBondContact O-N 3.34Å; N433-D436 VanDerWaalsContact O-N 3.1Å
437	I	91.3	Very high	90.4	Very high	1 Å²	1	4.4 Å²	4.4	1%	0.005	2%	0.022	C	C	.	.	H	α-helix	trans	-70.2	-46.1	-179.2	-68.7	178.2	0	0	0	112	P311 I315 N433 S499 K502 Q503 W505	P311-I437 HydrophobicContact CB-CD1 3.62Å; I315-I437 HydrophobicContact CD1-CD1 3.42Å; I315-I437 VanDerWaalsContact CD1-CD1 3.42Å; I315-I437 HydrophobicContact CG1-CD1 4.44Å; N433-I437 WeakPolarHBondContact O-CG1 3.04Å; N433-I437 PolarHBondContact O-N 2.95Å; N433-I437 VanDerWaalsContact O-N 3.07Å; I437-S499 WeakPolarHBondContact CG1-O 3.48Å; I437-K502 WeakPolarHBondContact O-CA 3.35Å; I437-Q503 HydrophobicContact CB-CG 4.32Å; I437-Q503 HydrophobicContact CG2-CB 4.31Å; I437-Q503 HydrophobicContact CG2-CG 3.29Å; I437-Q503 PolarHBondContact O-N 3.49Å; I437-W505 HydrophobicContact CG2-CH2 3.98Å; I437-W505 HydrophobicContact CG2-CZ2 4Å
438	A	88.4	Confident	90.5	Very high	0 Å²	0	4.7 Å²	4.7	0%	0	2%	0.024	C	C	.	.			trans	-153	82.6	-176.8	0	0	0	0	0	112.4	H434 R440 Y441 A442 L445 W505 A506	H434-A438 PolarHBondContact O-N 3.34Å; A438-R440 VanDerWaalsContact C-N 3.25Å; A438-R440 PolarHBondContact O-N 3.35Å; A438-R440 VanDerWaalsContact O-N 3.15Å; A438-Y441 CarbonylContact O-C 3.56Å; A438-Y441 PolarHBondContact O-N 2.92Å; A438-Y441 VanDerWaalsContact O-N 3.11Å; A438-A442 PolarHBondContact O-N 3.4Å; A438-L445 HydrophobicContact CB-CD1 3.78Å; A438-W505 HydrophobicContact CB-CE3 4.42Å; A438-W505 HydrophobicContact CB-CH2 3.56Å; A438-W505 HydrophobicContact CB-CZ3 3.36Å; A438-A506 HydrophobicContact CB-CB 3.7Å
439	P	84.6	Confident	90.8	Very high	17 Å²	17	4.8 Å²	4.8	11%	0.11	2%	0.024	C	C	.	.	G	3₁₀ helix	trans	-51.8	-40.9	-178.7	-21.3	24.3	0	0	0	113.9	S203 L435 A442	S203-P439 WeakPolarHBondContact CB-O 3.34Å; L435-P439 WeakPolarHBondContact O-CD 3.49Å; L435-P439 VanDerWaalsContact O-CG 3.22Å; L435-P439 WeakPolarHBondContact O-CG 3.24Å; P439-A442 WeakPolarHBondContact O-CB 3.35Å; P439-A442 PolarHBondContact O-N 2.86Å
440	R	82.9	Confident	90.9	Very high	19 Å²	19	5.5 Å²	5.5	7%	0.072	3%	0.028	C	C	.	.	G	3₁₀ helix	trans	-66.8	-37	-178.3	-65.9	174.4	69.6	-166.6	7.6	113.4	L293 A438 P508	L293-R440 HydrophobicContact CD2-CB 4.39Å; L293-R440 HydrophobicContact CD2-CG 4.16Å; A438-R440 VanDerWaalsContact C-N 3.25Å; A438-R440 PolarHBondContact O-N 3.35Å; A438-R440 VanDerWaalsContact O-N 3.15Å; R440-P508 VanDerWaalsContact NH1-N 3.18Å
441	Y	87.8	Confident	90.8	Very high	13 Å²	13	5.9 Å²	5.9	5%	0.051	3%	0.033	C	C	.	.	G	3₁₀ helix	trans	-103.3	9.5	-177.1	-57.3	-63.8	0	0	0	112.6	T301 P302 F306 A438 S443 I444 L445 W505	T301-Y441 HydrophobicContact CG2-CE1 4.44Å; P302-Y441 HydrophobicContact CG-CE2 4.29Å; F306-Y441 AromaticContact CE1-CD2 3.9Å; F306-Y441 HydrophobicContact CE1-CD2 3.9Å; F306-Y441 HydrophobicContact CE1-CE2 4.4Å; F306-Y441 HydrophobicContact CE1-CG 4.06Å; F306-Y441 AromaticContact CZ-CD1 3.85Å; F306-Y441 HydrophobicContact CZ-CD1 3.85Å; F306-Y441 AromaticContact CZ-CD2 3.84Å; F306-Y441 HydrophobicContact CZ-CD2 3.84Å; F306-Y441 HydrophobicContact CZ-CE1 4.36Å; F306-Y441 HydrophobicContact CZ-CE2 4.34Å; F306-Y441 AromaticContact CZ-CG 3.56Å; F306-Y441 HydrophobicContact CZ-CG 3.56Å; A438-Y441 CarbonylContact O-C 3.56Å; A438-Y441 PolarHBondContact O-N 2.92Å; A438-Y441 VanDerWaalsContact O-N 3.11Å; Y441-S443 VanDerWaalsContact C-N 3.27Å; Y441-S443 PolarHBondContact O-N 2.92Å; Y441-I444 HydrophobicContact CD1-CD1 4.28Å; Y441-I444 PolarHBondContact O-N 3.43Å; Y441-L445 PolarHBondContact O-N 3.46Å; Y441-W505 HydrophobicContact CD2-CE3 4.33Å; Y441-W505 HydrophobicContact CD2-CZ3 4.13Å
442	A	88.8	Confident	90.9	Very high	0 Å²	0	7.9 Å²	7.9	0%	0	5%	0.045	C	C	.	.	H	α-helix	trans	-56.2	-38.8	-173.2	0	0	0	0	0	112.8	H199 L435 A438 P439 M446	H199-A442 HydrophobicContact CB-CB 4.46Å; L435-A442 HydrophobicContact CD2-CB 3.77Å; L435-A442 HydrophobicContact CG-CB 4.4Å; A438-A442 PolarHBondContact O-N 3.4Å; P439-A442 WeakPolarHBondContact O-CB 3.35Å; P439-A442 PolarHBondContact O-N 2.86Å; A442-M446 VanDerWaalsContact O-CB 3.25Å; A442-M446 WeakPolarHBondContact O-CB 3.26Å; A442-M446 PolarHBondContact O-N 3.19Å
443	S	90.9	Very high	90.8	Very high	4 Å²	4	7.9 Å²	7.9	3%	0.028	5%	0.045	C	C	.	.	H	α-helix	trans	-61.5	-44.3	176.1	-48.5	0	0	0	0	112.2	G143 P196 G200 Y441 G447	G143-S443 WeakPolarHBondContact CA-O 3.3Å; G143-S443 WeakPolarHBondContact O-CB 3.41Å; P196-S443 WeakPolarHBondContact CB-O 3.44Å; P196-S443 PolarHBondContact O-OG 3.4Å; G200-S443 WeakPolarHBondContact CA-OG 3.37Å; G200-S443 PolarHBondContact N-OG 2.96Å; Y441-S443 VanDerWaalsContact C-N 3.27Å; Y441-S443 PolarHBondContact O-N 2.92Å; S443-G447 PolarHBondContact O-N 3.49Å
444	I	92.1	Very high	90.4	Very high	0 Å²	0	8 Å²	8	0%	0	5%	0.046	C	C	.	.	H	α-helix	trans	-68.6	-46.3	-179.2	-57.4	175.6	0	0	0	109.9	Y144 T301 W303 F306 Y441 M446 G447 I448	Y144-I444 HydrophobicContact CD2-CD1 4.24Å; T301-I444 HydrophobicContact CG2-CD1 4.04Å; W303-I444 HydrophobicContact CH2-CG2 4.22Å; W303-I444 HydrophobicContact CZ3-CG2 4.23Å; F306-I444 HydrophobicContact CE2-CG2 4.37Å; Y441-I444 HydrophobicContact CD1-CD1 4.28Å; Y441-I444 PolarHBondContact O-N 3.43Å; I444-M446 PolarHBondContact O-N 3.33Å; I444-G447 PolarHBondContact O-N 3.33Å; I444-G447 VanDerWaalsContact O-N 3.15Å; I444-I448 HydrophobicContact CG2-CD1 4.04Å; I444-I448 WeakPolarHBondContact O-CG1 3.35Å; I444-I448 PolarHBondContact O-N 2.91Å
445	L	92.9	Very high	90.1	Very high	7 Å²	7	11.9 Å²	11.9	4%	0.037	7%	0.066	C	C	.	.	H	α-helix	trans	-63	-41.9	179.3	-65	174.9	0	0	0	111.7	F306 V312 A438 Y441 G447 I448 S449 W505	F306-L445 HydrophobicContact CB-CD2 4.39Å; F306-L445 HydrophobicContact CD1-CD2 4.4Å; F306-L445 HydrophobicContact CD2-CD2 4.39Å; F306-L445 HydrophobicContact CG-CD2 4.17Å; V312-L445 HydrophobicContact CG1-CD2 4.17Å; V312-L445 HydrophobicContact CG2-CD2 4.19Å; A438-L445 HydrophobicContact CB-CD1 3.78Å; Y441-L445 PolarHBondContact O-N 3.46Å; L445-G447 VanDerWaalsContact C-N 3.34Å; L445-I448 PolarHBondContact O-N 3.46Å; L445-S449 VanDerWaalsContact O-CB 3.28Å; L445-S449 WeakPolarHBondContact O-CB 3.32Å; L445-S449 PolarHBondContact O-N 2.91Å; L445-W505 HydrophobicContact CD1-CH2 3.92Å; L445-W505 HydrophobicContact CD1-CZ3 4.44Å
446	M	93.3	Very high	89.8	Confident	1 Å²	1	12 Å²	12	1%	0.005	7%	0.067	C	C	.	.	H	α-helix	trans	-61.7	-43	172.9	173.8	50.6	75.4	0	0	111	H199 N431 H434 A442 I444 I448 S449 N450	H199-M446 HydrophobicContact CB-CB 4.44Å; H199-M446 WeakPolarHBondContact CE1-CE 3.06Å; H199-M446 VanDerWaalsContact NE2-CE 3.29Å; H199-M446 WeakPolarHBondContact NE2-CE 3.43Å; N431-M446 WeakPolarHBondContact OD1-CE 2.88Å; H434-M446 WeakPolarHBondContact CE1-CE 3.43Å; H434-M446 WeakPolarHBondContact ND1-CE 3.46Å; A442-M446 VanDerWaalsContact O-CB 3.25Å; A442-M446 WeakPolarHBondContact O-CB 3.26Å; A442-M446 PolarHBondContact O-N 3.19Å; I444-M446 PolarHBondContact O-N 3.33Å; M446-I448 PolarHBondContact O-N 2.95Å; M446-S449 PolarHBondContact O-N 3.46Å; M446-N450 WeakPolarHBondContact O-CB 3.19Å; M446-N450 PolarHBondContact O-N 3.04Å; M446-N450 HydrophobicContact SD-CB 4.04Å
447	G	93	Very high	89.1	Confident	0 Å²	0	11.8 Å²	11.8	0%	0	7%	0.068	C	C	.	.	H	α-helix	trans	-58.1	-46.7	175	0	0	0	0	0	113	Q139 S443 I444 L445 G451	Q139-G447 WeakPolarHBondContact CB-O 3.39Å; Q139-G447 VanDerWaalsContact O-CA 3.27Å; Q139-G447 WeakPolarHBondContact O-CA 3.39Å; S443-G447 PolarHBondContact O-N 3.49Å; I444-G447 PolarHBondContact O-N 3.33Å; I444-G447 VanDerWaalsContact O-N 3.15Å; L445-G447 VanDerWaalsContact C-N 3.34Å; G447-G451 PolarHBondContact O-N 2.86Å
448	I	93.6	Very high	88.6	Confident	10 Å²	10	15.7 Å²	15.7	5%	0.051	9%	0.087	C	C	.	.	H	α-helix	trans	-63.5	-50.8	177.1	-64.9	166.6	0	0	0	110.6	I140 W303 F307 I316 I444 L445 M446 N450 G451 V452	I140-I448 HydrophobicContact CG1-CG1 4.38Å; I140-I448 HydrophobicContact CG2-CG1 4.5Å; W303-I448 HydrophobicContact CZ3-CD1 4.28Å; F307-I448 HydrophobicContact CE1-CG2 4.35Å; F307-I448 HydrophobicContact CZ-CD1 4.13Å; I316-I448 HydrophobicContact CD1-CG2 4.06Å; I444-I448 HydrophobicContact CG2-CD1 4.04Å; I444-I448 WeakPolarHBondContact O-CG1 3.35Å; I444-I448 PolarHBondContact O-N 2.91Å; L445-I448 PolarHBondContact O-N 3.46Å; M446-I448 PolarHBondContact O-N 2.95Å; I448-N450 PolarHBondContact O-N 3.37Å; I448-G451 PolarHBondContact O-N 3.43Å; I448-V452 WeakPolarHBondContact O-CG2 3.26Å; I448-V452 PolarHBondContact O-N 3.47Å
449	S	93.9	Very high	88.4	Confident	2 Å²	2	18.4 Å²	18.4	1%	0.014	10%	0.103	C	C	.	.	H	α-helix	trans	-59.4	-46.4	-179.1	179.9	0	0	0	0	112	N319 H434 L445 M446 V452 G453	N319-S449 VanDerWaalsContact CB-OG 3.31Å; N319-S449 WeakPolarHBondContact CB-OG 3.42Å; N319-S449 PolarHBondContact ND2-O 3.47Å; N319-S449 PolarHBondContact ND2-OG 3.04Å; H434-S449 VanDerWaalsContact NE2-CB 3.27Å; H434-S449 WeakPolarHBondContact NE2-CB 3.13Å; H434-S449 PolarHBondContact NE2-OG 2.92Å; L445-S449 VanDerWaalsContact O-CB 3.28Å; L445-S449 WeakPolarHBondContact O-CB 3.32Å; L445-S449 PolarHBondContact O-N 2.91Å; M446-S449 PolarHBondContact O-N 3.46Å; S449-V452 PolarHBondContact O-N 2.91Å; S449-G453 PolarHBondContact O-N 3.07Å
450	N	92.4	Very high	88.4	Confident	15 Å²	15	17.6 Å²	17.6	8%	0.08	10%	0.098	C	C	.	.	H	α-helix	trans	-71.8	-32.8	179.6	-161.4	41.3	0	0	0	112.6	Q139 N319 M446 I448 G453 T454	Q139-N450 VanDerWaalsContact CD-ND2 3.29Å; Q139-N450 PolarHBondContact NE2-ND2 3.01Å; Q139-N450 PolarHBondContact OE1-ND2 3.45Å; N319-N450 WeakPolarHBondContact ND2-CA 3.35Å; N319-N450 PolarHBondContact ND2-N 3.02Å; M446-N450 WeakPolarHBondContact O-CB 3.19Å; M446-N450 PolarHBondContact O-N 3.04Å; M446-N450 HydrophobicContact SD-CB 4.04Å; I448-N450 PolarHBondContact O-N 3.37Å; N450-G453 PolarHBondContact O-N 3.06Å; N450-T454 WeakPolarHBondContact O-CB 3.45Å; N450-T454 WeakPolarHBondContact O-CG2 3.46Å; N450-T454 PolarHBondContact O-N 3.5Å; N450-T454 PolarHBondContact O-OG1 2.97Å
451	G	91.6	Very high	88.3	Confident	10 Å²	10	18.7 Å²	18.7	10%	0.103	11%	0.107	C	C	.	.	H	α-helix	trans	-58.4	-49.4	170	0	0	0	0	0	112.4	G447 I448 T454 L455	G447-G451 PolarHBondContact O-N 2.86Å; I448-G451 PolarHBondContact O-N 3.43Å; G451-T454 PolarHBondContact O-N 3.31Å; G451-T454 PolarHBondContact O-OG1 3.14Å; G451-L455 PolarHBondContact O-N 3.34Å
452	V	92.1	Very high	88.2	Confident	54 Å²	54	23.7 Å²	23.7	33%	0.327	13%	0.134	S	C	.	.	H	α-helix	trans	-67.7	-40	176.9	178.5	0	0	0	0	111.5	I316 F320 I448 S449 T454 L455 S456	I316-V452 HydrophobicContact CG2-CB 3.93Å; I316-V452 HydrophobicContact CG2-CG1 3.71Å; I316-V452 HydrophobicContact CG2-CG2 4.13Å; F320-V452 HydrophobicContact CD2-CG1 4.35Å; I448-V452 WeakPolarHBondContact O-CG2 3.26Å; I448-V452 PolarHBondContact O-N 3.47Å; S449-V452 PolarHBondContact O-N 2.91Å; V452-T454 PolarHBondContact O-N 2.97Å; V452-L455 WeakPolarHBondContact O-CB 3.33Å; V452-L455 PolarHBondContact O-N 2.97Å; V452-S456 PolarHBondContact O-N 3.33Å
453	G	90.3	Very high	88.1	Confident	0 Å²	0	26.5 Å²	26.5	0%	0	15%	0.148	C	C	.	.	H	α-helix	trans	-59.9	-44.7	176	0	0	0	0	0	112.8	S323 S449 N450 L455 S456	S323-G453 WeakPolarHBondContact CB-O 3.34Å; S323-G453 WeakPolarHBondContact OG-CA 3.35Å; S323-G453 PolarHBondContact OG-O 3.17Å; S449-G453 PolarHBondContact O-N 3.07Å; N450-G453 PolarHBondContact O-N 3.06Å; G453-L455 VanDerWaalsContact C-N 3.32Å; G453-L455 PolarHBondContact O-N 3.22Å; G453-S456 WeakPolarHBondContact O-CB 3.33Å; G453-S456 PolarHBondContact O-N 3.47Å; G453-S456 VanDerWaalsContact O-N 3.16Å
454	T	86.8	Confident	87.9	Confident	2 Å²	2	26.7 Å²	26.7	1%	0.012	15%	0.149	C	C	.	.	H	α-helix	trans	-67.2	-30.8	-179.8	49.5	0	0	0	0	113.4	Y135 N450 G451 V452 S456 G457 M458	Y135-T454 HydrophobicContact CD1-CG2 3.73Å; Y135-T454 HydrophobicContact CE1-CG2 3.48Å; Y135-T454 VanDerWaalsContact CE1-CG2 3.48Å; N450-T454 WeakPolarHBondContact O-CB 3.45Å; N450-T454 WeakPolarHBondContact O-CG2 3.46Å; N450-T454 PolarHBondContact O-N 3.5Å; N450-T454 PolarHBondContact O-OG1 2.97Å; G451-T454 PolarHBondContact O-N 3.31Å; G451-T454 PolarHBondContact O-OG1 3.14Å; V452-T454 PolarHBondContact O-N 2.97Å; T454-S456 VanDerWaalsContact C-N 3.28Å; T454-S456 PolarHBondContact O-N 3.33Å; T454-G457 WeakPolarHBondContact O-CA 3.15Å; T454-G457 PolarHBondContact O-N 2.96Å; T454-M458 PolarHBondContact O-N 3.43Å
455	L	85.4	Confident	87.5	Confident	85 Å²	85	28.8 Å²	28.8	45%	0.445	17%	0.171	S	C	.	.	H	α-helix	trans	-59.4	-39.9	172.3	-175.2	64.9	0	0	0	111.9	G451 V452 G453 G457 M458 V459	G451-L455 PolarHBondContact O-N 3.34Å; V452-L455 WeakPolarHBondContact O-CB 3.33Å; V452-L455 PolarHBondContact O-N 2.97Å; G453-L455 VanDerWaalsContact C-N 3.32Å; G453-L455 PolarHBondContact O-N 3.22Å; L455-G457 PolarHBondContact O-N 3.46Å; L455-M458 PolarHBondContact O-N 2.83Å; L455-M458 VanDerWaalsContact O-N 3.11Å; L455-V459 WeakPolarHBondContact O-CG2 3.49Å; L455-V459 PolarHBondContact O-N 2.85Å
456	S	83.3	Confident	87.3	Confident	1 Å²	1	31.3 Å²	31.3	1%	0.007	19%	0.192	C	C	.	.	H	α-helix	trans	-54.2	-40.4	172.8	-168.4	0	0	0	0	112	F320 W324 V452 G453 T454 M458 V459 C460	F320-S456 VanDerWaalsContact CE2-CB 3.49Å; F320-S456 PolarHBondContact O-OG 3.05Å; W324-S456 WeakPolarHBondContact CB-OG 3.28Å; W324-S456 PolarHBondContact N-OG 3.3Å; V452-S456 PolarHBondContact O-N 3.33Å; G453-S456 WeakPolarHBondContact O-CB 3.33Å; G453-S456 PolarHBondContact O-N 3.47Å; G453-S456 VanDerWaalsContact O-N 3.16Å; T454-S456 VanDerWaalsContact C-N 3.28Å; T454-S456 PolarHBondContact O-N 3.33Å; S456-M458 VanDerWaalsContact C-N 3.32Å; S456-M458 PolarHBondContact O-N 3.4Å; S456-V459 PolarHBondContact O-N 3.33Å; S456-C460 VanDerWaalsContact O-CB 3.29Å; S456-C460 WeakPolarHBondContact O-CB 3.48Å; S456-C460 PolarHBondContact O-N 3.49Å
457	G	75.2	Confident	87.1	Confident	7 Å²	7	34 Å²	34	7%	0.072	21%	0.206	C	C	.	.	H	α-helix	trans	-67.2	-26.3	178.6	0	0	0	0	0	115.7	Y327 T454 L455 P461	Y327-G457 VanDerWaalsContact CE2-CA 3.49Å; T454-G457 WeakPolarHBondContact O-CA 3.15Å; T454-G457 PolarHBondContact O-N 2.96Å; L455-G457 PolarHBondContact O-N 3.46Å; G457-P461 WeakPolarHBondContact O-CD 3.29Å; G457-P461 WeakPolarHBondContact O-CG 3.36Å
458	M	81	Confident	86.9	Confident	82 Å²	82	34.8 Å²	34.8	40%	0.404	21%	0.21	S	C	.	.	H	α-helix	trans	-80	-36.2	174.9	-164.2	170.8	89.1	0	0	111.3	I136 T454 L455 S456 I462	I136-M458 HydrophobicContact CD1-SD 4.39Å; T454-M458 PolarHBondContact O-N 3.43Å; L455-M458 PolarHBondContact O-N 2.83Å; L455-M458 VanDerWaalsContact O-N 3.11Å; S456-M458 VanDerWaalsContact C-N 3.32Å; S456-M458 PolarHBondContact O-N 3.4Å; M458-I462 WeakPolarHBondContact O-CD1 3.36Å
459	V	84.6	Confident	86.6	Confident	58 Å²	58	41.8 Å²	41.8	35%	0.352	24%	0.241	S	C	.	.	H	α-helix	trans	-77.6	-37.9	-177.7	175.1	0	0	0	0	111.8	L455 S456 I462 I463	L455-V459 WeakPolarHBondContact O-CG2 3.49Å; L455-V459 PolarHBondContact O-N 2.85Å; S456-V459 PolarHBondContact O-N 3.33Å; V459-I462 PolarHBondContact O-N 3.25Å; V459-I463 HydrophobicContact CG1-CD1 3.51Å; V459-I463 HydrophobicContact CG1-CG1 4.1Å; V459-I463 PolarHBondContact O-N 3.25Å; V459-I463 VanDerWaalsContact O-N 3.14Å
460	C	84.5	Confident	86.3	Confident	0 Å²	0	48 Å²	48	0%	0	27%	0.273	C	S	.	.	H	α-helix	trans	-56.4	-50.9	-174.8	174.3	0	0	0	0	113.7	W324 S456 I462 I463 V464	W324-C460 HydrophobicContact CD2-CB 4.31Å; S456-C460 VanDerWaalsContact O-CB 3.29Å; S456-C460 WeakPolarHBondContact O-CB 3.48Å; S456-C460 PolarHBondContact O-N 3.49Å; C460-I462 VanDerWaalsContact C-N 3.29Å; C460-I462 PolarHBondContact O-N 3.33Å; C460-I463 PolarHBondContact O-N 3.42Å; C460-V464 WeakPolarHBondContact O-CG2 3.32Å; C460-V464 PolarHBondContact O-N 2.68Å
461	P	81.1	Confident	86	Confident	41 Å²	41	53.2 Å²	53.2	27%	0.266	30%	0.296	S	S	.	.	H	α-helix	trans	-61.8	-34.9	-179.8	-26	37.1	0	0	0	113.7	I331 G457 G465	I331-P461 HydrophobicContact CD1-CB 4.34Å; I331-P461 HydrophobicContact CD1-CG 3.42Å; I331-P461 VanDerWaalsContact CD1-CG 3.42Å; G457-P461 WeakPolarHBondContact O-CD 3.29Å; G457-P461 WeakPolarHBondContact O-CG 3.36Å; P461-G465 PolarHBondContact O-N 3.41Å
462	I	85.1	Confident	85.9	Confident	119 Å²	119	54.2 Å²	54.2	61%	0.61	30%	0.301	S	S	*	.	H	α-helix	trans	-65.7	-44.7	178.3	-58.6	172.4	0	0	0	109.8	M458 V459 C460 A466	M458-I462 WeakPolarHBondContact O-CD1 3.36Å; V459-I462 PolarHBondContact O-N 3.25Å; C460-I462 VanDerWaalsContact C-N 3.29Å; C460-I462 PolarHBondContact O-N 3.33Å; I462-A466 VanDerWaalsContact O-CB 3.31Å; I462-A466 WeakPolarHBondContact O-CB 3.46Å; I462-A466 PolarHBondContact O-N 2.85Å
463	I	87.1	Confident	85.7	Confident	59 Å²	59	55.1 Å²	55.1	30%	0.303	30%	0.299	S	S	.	.	H	α-helix	trans	-65.1	-47.7	177.8	-67.7	177.3	0	0	0	110.5	W324 V459 C460 G465 A466 M467	W324-I463 HydrophobicContact CH2-CD1 3.61Å; W324-I463 HydrophobicContact CZ2-CD1 4.46Å; W324-I463 HydrophobicContact CZ3-CD1 4.35Å; V459-I463 HydrophobicContact CG1-CD1 3.51Å; V459-I463 HydrophobicContact CG1-CG1 4.1Å; V459-I463 PolarHBondContact O-N 3.25Å; V459-I463 VanDerWaalsContact O-N 3.14Å; C460-I463 PolarHBondContact O-N 3.42Å; I463-G465 PolarHBondContact O-N 3.39Å; I463-A466 PolarHBondContact O-N 3.34Å; I463-M467 HydrophobicContact CG2-CG 4.39Å; I463-M467 HydrophobicContact CG2-SD 3.99Å; I463-M467 WeakPolarHBondContact O-CB 3.23Å; I463-M467 VanDerWaalsContact O-CG 3.31Å; I463-M467 WeakPolarHBondContact O-CG 3.34Å; I463-M467 PolarHBondContact O-N 3.33Å
464	V	86.4	Confident	85.8	Confident	8 Å²	8	60.3 Å²	60.3	5%	0.048	32%	0.323	C	S	.	.	H	α-helix	trans	-60.1	-49.4	179.5	176.7	0	0	0	0	110.4	L328 C460 A466 M467 T468 W476 V479	L328-V464 HydrophobicContact CD1-CG2 3.64Å; C460-V464 WeakPolarHBondContact O-CG2 3.32Å; C460-V464 PolarHBondContact O-N 2.68Å; V464-A466 VanDerWaalsContact C-N 3.26Å; V464-A466 PolarHBondContact O-N 3.47Å; V464-M467 PolarHBondContact O-N 2.82Å; V464-T468 HydrophobicContact CG1-CG2 4.17Å; V464-T468 PolarHBondContact O-N 3.49Å; V464-T468 PolarHBondContact O-OG1 3.37Å; V464-W476 HydrophobicContact CG1-CH2 4.14Å; V464-W476 HydrophobicContact CG1-CZ3 4.12Å; V464-V479 HydrophobicContact CG1-CG1 4.33Å; V464-V479 HydrophobicContact CG1-CG2 4.44Å; V464-V479 HydrophobicContact CG2-CG1 3.95Å
465	G	84.4	Confident	86	Confident	44 Å²	44	61.4 Å²	61.4	45%	0.454	33%	0.328	S	S	.	.	H	α-helix	trans	-62.1	-32	178.4	0	0	0	0	0	113.7	P461 I463	P461-G465 PolarHBondContact O-N 3.41Å; I463-G465 PolarHBondContact O-N 3.39Å
466	A	87.4	Confident	86.3	Confident	59 Å²	59	57.5 Å²	57.5	49%	0.488	31%	0.307	S	S	.	.	H	α-helix	trans	-73.6	-28.7	174	0	0	0	0	0	113.2	I462 I463 V464	I462-A466 VanDerWaalsContact O-CB 3.31Å; I462-A466 WeakPolarHBondContact O-CB 3.46Å; I462-A466 PolarHBondContact O-N 2.85Å; I463-A466 PolarHBondContact O-N 3.34Å; V464-A466 VanDerWaalsContact C-N 3.26Å; V464-A466 PolarHBondContact O-N 3.47Å
467	M	89.2	Confident	86.8	Confident	58 Å²	58	59.2 Å²	59.2	29%	0.286	32%	0.315	S	S	.	.	H	α-helix	trans	-84.3	-30.9	179.3	-73.1	-171.9	67.3	0	0	113.5	I463 V464 K469 E475 V479 I482	I463-M467 HydrophobicContact CG2-CG 4.39Å; I463-M467 HydrophobicContact CG2-SD 3.99Å; I463-M467 WeakPolarHBondContact O-CB 3.23Å; I463-M467 VanDerWaalsContact O-CG 3.31Å; I463-M467 WeakPolarHBondContact O-CG 3.34Å; I463-M467 PolarHBondContact O-N 3.33Å; V464-M467 PolarHBondContact O-N 2.82Å; M467-K469 PolarHBondContact O-N 3.04Å; M467-E475 WeakPolarHBondContact O-CB 3.39Å; M467-E475 WeakPolarHBondContact O-CG 3.45Å; M467-V479 HydrophobicContact CB-CG2 4.06Å; M467-V479 HydrophobicContact CE-CG2 4.24Å; M467-V479 HydrophobicContact SD-CG2 4.28Å; M467-I482 HydrophobicContact CE-CD1 3.55Å; M467-I482 HydrophobicContact SD-CD1 3.62Å
468	T	89.3	Confident	87.7	Confident	16 Å²	16	65.9 Å²	65.9	10%	0.098	34%	0.339	C	S	.	.			trans	-100.4	42.7	-175.6	63.1	0	0	0	0	112.4	V464 K471 E475 W476 V479	V464-T468 HydrophobicContact CG1-CG2 4.17Å; V464-T468 PolarHBondContact O-N 3.49Å; V464-T468 PolarHBondContact O-OG1 3.37Å; T468-K471 PolarHBondContact O-N 3.24Å; T468-E475 WeakPolarHBondContact CA-OE2 3.44Å; T468-E475 HydrophobicContact CG2-CB 4.44Å; T468-W476 HydrophobicContact CG2-CD2 3.95Å; T468-W476 HydrophobicContact CG2-CE3 4.27Å; T468-W476 HydrophobicContact CG2-CG 4.42Å; T468-W476 HydrophobicContact CG2-CH2 4.35Å; T468-W476 HydrophobicContact CG2-CZ2 4.04Å; T468-W476 HydrophobicContact CG2-CZ3 4.46Å; T468-V479 HydrophobicContact CG2-CG2 3.93Å
469	K	88.2	Confident	88.2	Confident	158 Å²	158	62.3 Å²	62.3	69%	0.687	32%	0.322	S	S	*	.	S	Bend	trans	-69.7	-39	-176.1	-75.1	-176	-177.6	-176.7	0	112.9	M467 K471 E475	M467-K469 PolarHBondContact O-N 3.04Å; K469-K471 VanDerWaalsContact C-N 3.26Å; K469-E475 PolarHBondContact N-OE2 3.37Å
470	N	86.8	Confident	88.6	Confident	131 Å²	131	59.8 Å²	59.8	70%	0.701	31%	0.306	S	S	*	.	S	Bend	trans	-87.9	-1.6	179.6	-53.4	-56.8	0	0	0	112	S472 E475	N470-S472 PolarHBondContact O-N 2.87Å; N470-S472 VanDerWaalsContact O-N 3.15Å; N470-E475 WeakPolarHBondContact CA-OE2 3.17Å; N470-E475 WeakPolarHBondContact CB-OE1 3.23Å; N470-E475 PolarHBondContact N-OE1 3.48Å; N470-E475 VanDerWaalsContact N-OE1 3.09Å; N470-E475 PolarHBondContact N-OE2 3.46Å; N470-E475 PolarHBondContact ND2-OE1 3.49Å
471	K	87.1	Confident	89.1	Confident	125 Å²	125	62.3 Å²	62.3	54%	0.543	32%	0.319	S	S	.	.			trans	53.2	33.7	-178.5	-57	172.3	173.6	-101.9	0	111.1	E339 T468 K469 E475	E339-K471 HydrophobicContact CB-CB 4.47Å; E339-K471 HydrophobicContact CG-CB 4.29Å; E339-K471 HydrophobicContact CG-CD 4.39Å; E339-K471 HydrophobicContact CG-CG 4.44Å; E339-K471 WeakPolarHBondContact OE1-CD 3.22Å; E339-K471 WeakPolarHBondContact OE1-CG 3.31Å; E339-K471 IonicContact OE1-NZ 2.88Å; E339-K471 PolarHBondContact OE1-NZ 3.45Å; T468-K471 PolarHBondContact O-N 3.24Å; K469-K471 VanDerWaalsContact C-N 3.26Å; K471-E475 PolarHBondContact N-OE2 2.98Å
472	S	88.8	Confident	89.7	Confident	32 Å²	32	63.3 Å²	63.3	22%	0.224	32%	0.322	C	S	.	.			trans	-88.6	159.4	-176.5	101.4	0	0	0	0	110.3	N470 E474 E475 W476	N470-S472 PolarHBondContact O-N 2.87Å; N470-S472 VanDerWaalsContact O-N 3.15Å; S472-E474 VanDerWaalsContact C-N 3.33Å; S472-E474 VanDerWaalsContact CB-OE2 3.29Å; S472-E474 WeakPolarHBondContact CB-OE2 3.43Å; S472-E474 PolarHBondContact O-N 3.29Å; S472-E474 PolarHBondContact OG-N 3.25Å; S472-E474 PolarHBondContact OG-OE2 2.7Å; S472-E475 PolarHBondContact N-OE2 2.93Å; S472-E475 PolarHBondContact O-N 3.49Å; S472-E475 PolarHBondContact OG-N 2.95Å; S472-W476 VanDerWaalsContact O-CD1 3.27Å; S472-W476 PolarHBondContact O-N 3.14Å
473	R	88.3	Confident	90	Very high	72 Å²	72	57.6 Å²	57.6	27%	0.272	29%	0.293	S	S	.	.	H	α-helix	trans	-68.2	-36.6	-179.3	-172.5	174.1	-172	-174.3	-16	112.5	V340 S406 H407 E475 W476 Q477	V340-R473 HydrophobicContact CG1-CG 4.04Å; S406-R473 VanDerWaalsContact C-NH2 3.26Å; S406-R473 PolarHBondContact O-NH2 2.81Å; H407-R473 PolarHBondContact CE1-NH2 3.05Å; H407-R473 PolarHBondContact ND1-NH1 3.01Å; H407-R473 VanDerWaalsContact ND1-NH1 3.18Å; H407-R473 PolarHBondContact ND1-NH2 3.38Å; R473-E475 VanDerWaalsContact C-N 3.31Å; R473-W476 PolarHBondContact O-N 3.44Å; R473-Q477 WeakPolarHBondContact O-CG 3.48Å; R473-Q477 PolarHBondContact O-N 2.87Å
474	E	91.2	Very high	90.3	Very high	109 Å²	109	54.9 Å²	54.9	51%	0.509	28%	0.279	S	S	.	.	H	α-helix	trans	-63.3	-40.3	178.8	-57	77.1	-163.1	0	0	110.6	S472 W476 Q477 Y478	S472-E474 VanDerWaalsContact C-N 3.33Å; S472-E474 VanDerWaalsContact CB-OE2 3.29Å; S472-E474 WeakPolarHBondContact CB-OE2 3.43Å; S472-E474 PolarHBondContact O-N 3.29Å; S472-E474 PolarHBondContact OG-N 3.25Å; S472-E474 PolarHBondContact OG-OE2 2.7Å; E474-W476 VanDerWaalsContact C-N 3.34Å; E474-W476 PolarHBondContact O-N 3.01Å; E474-Q477 WeakPolarHBondContact O-CB 3.45Å; E474-Q477 PolarHBondContact O-N 3.09Å; E474-Y478 WeakPolarHBondContact O-CD2 3.21Å; E474-Y478 PolarHBondContact O-N 3.47Å; E474-Y478 VanDerWaalsContact O-N 3.1Å
475	E	92.7	Very high	90.7	Very high	25 Å²	25	59.6 Å²	59.6	12%	0.117	30%	0.303	C	S	.	.	H	α-helix	trans	-58.6	-45.4	175.4	-67.3	174.7	158.4	0	0	111.3	M467 T468 K469 N470 K471 S472 R473 Q477 Y478 V479	M467-E475 WeakPolarHBondContact O-CB 3.39Å; M467-E475 WeakPolarHBondContact O-CG 3.45Å; T468-E475 WeakPolarHBondContact CA-OE2 3.44Å; T468-E475 HydrophobicContact CG2-CB 4.44Å; K469-E475 PolarHBondContact N-OE2 3.37Å; N470-E475 WeakPolarHBondContact CA-OE2 3.17Å; N470-E475 WeakPolarHBondContact CB-OE1 3.23Å; N470-E475 PolarHBondContact N-OE1 3.48Å; N470-E475 VanDerWaalsContact N-OE1 3.09Å; N470-E475 PolarHBondContact N-OE2 3.46Å; N470-E475 PolarHBondContact ND2-OE1 3.49Å; K471-E475 PolarHBondContact N-OE2 2.98Å; S472-E475 PolarHBondContact N-OE2 2.93Å; S472-E475 PolarHBondContact O-N 3.49Å; S472-E475 PolarHBondContact OG-N 2.95Å; R473-E475 VanDerWaalsContact C-N 3.31Å; E475-Q477 PolarHBondContact O-N 3.04Å; E475-Y478 PolarHBondContact O-N 3.5Å; E475-V479 WeakPolarHBondContact O-CG2 3.45Å; E475-V479 PolarHBondContact O-N 3.05Å; E475-V479 VanDerWaalsContact O-N 3.08Å
476	W	91.4	Very high	91.1	Very high	4 Å²	4	59.3 Å²	59.3	2%	0.015	29%	0.292	C	S	.	.	H	α-helix	trans	-65.1	-35.4	176.3	-77.3	107.3	0	0	0	113.1	A335 Y336 E339 V340 V464 T468 S472 R473 E474 Y478 V479 F480	A335-W476 HydrophobicContact CB-CH2 4.2Å; A335-W476 HydrophobicContact CB-CZ2 4.14Å; Y336-W476 HydrophobicContact CD2-CB 3.94Å; Y336-W476 AromaticContact CD2-CD2 3.63Å; Y336-W476 HydrophobicContact CD2-CD2 3.63Å; Y336-W476 AromaticContact CD2-CE3 3.78Å; Y336-W476 HydrophobicContact CD2-CE3 3.78Å; Y336-W476 AromaticContact CD2-CG 3.7Å; Y336-W476 HydrophobicContact CD2-CG 3.7Å; Y336-W476 HydrophobicContact CE2-CB 3.94Å; Y336-W476 HydrophobicContact CE2-CG 4.19Å; Y336-W476 HydrophobicContact CG-CD2 4.42Å; Y336-W476 HydrophobicContact CG-CE3 4.3Å; E339-W476 WeakPolarHBondContact OE2-CZ2 3.39Å; E339-W476 PolarHBondContact OE2-NE1 3.42Å; V340-W476 HydrophobicContact CG2-CB 4.23Å; V340-W476 VanDerWaalsContact CG2-CD1 3.41Å; V340-W476 HydrophobicContact CG2-CG 3.88Å; V464-W476 HydrophobicContact CG1-CH2 4.14Å; V464-W476 HydrophobicContact CG1-CZ3 4.12Å; T468-W476 HydrophobicContact CG2-CD2 3.95Å; T468-W476 HydrophobicContact CG2-CE3 4.27Å; T468-W476 HydrophobicContact CG2-CG 4.42Å; T468-W476 HydrophobicContact CG2-CH2 4.35Å; T468-W476 HydrophobicContact CG2-CZ2 4.04Å; T468-W476 HydrophobicContact CG2-CZ3 4.46Å; S472-W476 VanDerWaalsContact O-CD1 3.27Å; S472-W476 PolarHBondContact O-N 3.14Å; R473-W476 PolarHBondContact O-N 3.44Å; E474-W476 VanDerWaalsContact C-N 3.34Å; E474-W476 PolarHBondContact O-N 3.01Å; W476-Y478 VanDerWaalsContact C-N 3.33Å; W476-Y478 PolarHBondContact O-N 2.84Å; W476-V479 HydrophobicContact CE3-CB 4.48Å; W476-V479 HydrophobicContact CE3-CG1 4.47Å; W476-V479 PolarHBondContact O-N 3.38Å; W476-F480 HydrophobicContact CE3-CE2 4.3Å; W476-F480 WeakPolarHBondContact O-CD2 3.48Å; W476-F480 PolarHBondContact O-N 3.41Å
477	Q	93.8	Very high	91.3	Very high	37 Å²	37	56.5 Å²	56.5	17%	0.173	27%	0.269	C	S	.	.	H	α-helix	trans	-60.1	-43.8	173	-72.9	171.4	-21	0	0	111.5	G404 Y405 R473 E474 E475 F480 L481	G404-Q477 VanDerWaalsContact O-CG 3.32Å; G404-Q477 WeakPolarHBondContact O-CG 3.28Å; Y405-Q477 HydrophobicContact CD1-CG 4.17Å; Y405-Q477 HydrophobicContact CE1-CB 4.29Å; Y405-Q477 HydrophobicContact CE1-CG 4.19Å; R473-Q477 WeakPolarHBondContact O-CG 3.48Å; R473-Q477 PolarHBondContact O-N 2.87Å; E474-Q477 WeakPolarHBondContact O-CB 3.45Å; E474-Q477 PolarHBondContact O-N 3.09Å; E475-Q477 PolarHBondContact O-N 3.04Å; Q477-F480 PolarHBondContact O-N 3.18Å; Q477-L481 WeakPolarHBondContact O-CB 3.47Å; Q477-L481 PolarHBondContact O-N 3.48Å
478	Y	93.1	Very high	91.6	Very high	146 Å²	146	57.2 Å²	57.2	57%	0.573	27%	0.269	S	S	*	.	H	α-helix	trans	-63.9	-39	175.6	-78	-70.2	0	0	0	112.5	E474 E475 W476 L481 I482	E474-Y478 WeakPolarHBondContact O-CD2 3.21Å; E474-Y478 PolarHBondContact O-N 3.47Å; E474-Y478 VanDerWaalsContact O-N 3.1Å; E475-Y478 PolarHBondContact O-N 3.5Å; W476-Y478 VanDerWaalsContact C-N 3.33Å; W476-Y478 PolarHBondContact O-N 2.84Å; Y478-L481 HydrophobicContact CD1-CD2 4.39Å; Y478-L481 PolarHBondContact O-N 3.07Å; Y478-I482 WeakPolarHBondContact O-CG1 3.2Å; Y478-I482 PolarHBondContact O-N 3.07Å
479	V	92.8	Very high	91.9	Very high	7 Å²	7	58.2 Å²	58.2	4%	0.042	28%	0.283	C	S	.	.	H	α-helix	trans	-60	-48.3	176	171.7	0	0	0	0	111.3	L328 V464 M467 T468 E475 W476 I482 A483	L328-V479 HydrophobicContact CD1-CG1 3.77Å; V464-V479 HydrophobicContact CG1-CG1 4.33Å; V464-V479 HydrophobicContact CG1-CG2 4.44Å; V464-V479 HydrophobicContact CG2-CG1 3.95Å; M467-V479 HydrophobicContact CB-CG2 4.06Å; M467-V479 HydrophobicContact CE-CG2 4.24Å; M467-V479 HydrophobicContact SD-CG2 4.28Å; T468-V479 HydrophobicContact CG2-CG2 3.93Å; E475-V479 WeakPolarHBondContact O-CG2 3.45Å; E475-V479 PolarHBondContact O-N 3.05Å; E475-V479 VanDerWaalsContact O-N 3.08Å; W476-V479 HydrophobicContact CE3-CB 4.48Å; W476-V479 HydrophobicContact CE3-CG1 4.47Å; W476-V479 PolarHBondContact O-N 3.38Å; V479-I482 PolarHBondContact O-N 3.46Å; V479-A483 PolarHBondContact O-N 3.42Å
480	F	92.9	Very high	92.2	Very high	6 Å²	6	50.8 Å²	50.8	3%	0.026	25%	0.252	C	S	.	.	H	α-helix	trans	-68.2	-34.5	177.6	-76.2	-68.1	0	0	0	112.9	Y336 L400 V403 W476 Q477 A483 A484	Y336-F480 HydrophobicContact CD1-CE2 4.21Å; Y336-F480 HydrophobicContact CD1-CZ 4.2Å; Y336-F480 AromaticContact CD2-CE2 3.76Å; Y336-F480 HydrophobicContact CD2-CE2 3.76Å; Y336-F480 HydrophobicContact CD2-CZ 4.43Å; Y336-F480 HydrophobicContact CE1-CE2 4.1Å; Y336-F480 HydrophobicContact CE1-CZ 4.29Å; Y336-F480 HydrophobicContact CE2-CD2 4.42Å; Y336-F480 AromaticContact CE2-CE2 3.63Å; Y336-F480 HydrophobicContact CE2-CE2 3.63Å; Y336-F480 HydrophobicContact CG-CE2 4.03Å; Y336-F480 HydrophobicContact CG-CZ 4.25Å; Y336-F480 AromaticContact CZ-CE2 3.81Å; L400-F480 HydrophobicContact CD2-CD1 4.25Å; L400-F480 HydrophobicContact CD2-CE1 4.16Å; V403-F480 HydrophobicContact CG1-CE1 4.41Å; V403-F480 HydrophobicContact CG1-CZ 4.22Å; W476-F480 HydrophobicContact CE3-CE2 4.3Å; W476-F480 WeakPolarHBondContact O-CD2 3.48Å; W476-F480 PolarHBondContact O-N 3.41Å; Q477-F480 PolarHBondContact O-N 3.18Å; F480-A483 PolarHBondContact O-N 3.41Å; F480-A484 WeakPolarHBondContact O-CB 2.93Å; F480-A484 PolarHBondContact O-N 3.26Å
481	L	94.3	Very high	92.6	Very high	52 Å²	52	45.5 Å²	45.5	27%	0.272	22%	0.224	S	C	.	.	H	α-helix	trans	-61.2	-47.2	174.3	-178	67.1	0	0	0	111.4	L401 Q477 Y478 A483 A484 L485	L401-L481 HydrophobicContact CD2-CD1 3.78Å; Q477-L481 WeakPolarHBondContact O-CB 3.47Å; Q477-L481 PolarHBondContact O-N 3.48Å; Y478-L481 HydrophobicContact CD1-CD2 4.39Å; Y478-L481 PolarHBondContact O-N 3.07Å; L481-A483 PolarHBondContact O-N 3.28Å; L481-A484 PolarHBondContact O-N 2.93Å; L481-L485 HydrophobicContact CG-CD1 4.3Å; L481-L485 WeakPolarHBondContact O-CG 3.49Å; L481-L485 PolarHBondContact O-N 3.45Å
482	I	92.6	Very high	93	Very high	62 Å²	62	44.3 Å²	44.3	32%	0.318	22%	0.222	S	C	.	.	H	α-helix	trans	-61.3	-46	176.4	-68.5	169.2	0	0	0	110.4	W324 M467 Y478 V479 A484 L485 V486	W324-I482 HydrophobicContact CZ2-CG2 4.45Å; M467-I482 HydrophobicContact CE-CD1 3.55Å; M467-I482 HydrophobicContact SD-CD1 3.62Å; Y478-I482 WeakPolarHBondContact O-CG1 3.2Å; Y478-I482 PolarHBondContact O-N 3.07Å; V479-I482 PolarHBondContact O-N 3.46Å; I482-A484 VanDerWaalsContact C-N 3.29Å; I482-A484 PolarHBondContact O-N 3.2Å; I482-L485 PolarHBondContact O-N 3.3Å; I482-V486 HydrophobicContact CG2-CG2 4.3Å; I482-V486 VanDerWaalsContact O-CG2 3.31Å; I482-V486 WeakPolarHBondContact O-CG2 3.19Å; I482-V486 PolarHBondContact O-N 3.43Å
483	A	92.1	Very high	93.4	Very high	0 Å²	0	45.8 Å²	45.8	0%	0	23%	0.225	C	C	.	.	H	α-helix	trans	-57.4	-43.1	178.5	0	0	0	0	0	112	L328 V479 F480 L481 V486 H487	L328-A483 HydrophobicContact CD2-CB 3.59Å; V479-A483 PolarHBondContact O-N 3.42Å; F480-A483 PolarHBondContact O-N 3.41Å; L481-A483 PolarHBondContact O-N 3.28Å; A483-V486 PolarHBondContact O-N 3.2Å; A483-H487 PolarHBondContact O-N 3.24Å; A483-H487 PolarHBondContact O-ND1 3.33Å
484	A	94.1	Very high	93.8	Very high	1 Å²	1	42.4 Å²	42.4	1%	0.008	21%	0.212	C	C	.	.	H	α-helix	trans	-66.7	-42.9	177.1	0	0	0	0	0	112.7	A397 L401 F480 L481 I482 V486 H487 Y488	A397-A484 HydrophobicContact CB-CB 4.5Å; L401-A484 HydrophobicContact CD1-CB 3.99Å; L401-A484 HydrophobicContact CD2-CB 3.56Å; L401-A484 HydrophobicContact CG-CB 3.49Å; L401-A484 VanDerWaalsContact CG-CB 3.49Å; F480-A484 WeakPolarHBondContact O-CB 2.93Å; F480-A484 PolarHBondContact O-N 3.26Å; L481-A484 PolarHBondContact O-N 2.93Å; I482-A484 VanDerWaalsContact C-N 3.29Å; I482-A484 PolarHBondContact O-N 3.2Å; A484-V486 VanDerWaalsContact C-N 3.34Å; A484-V486 PolarHBondContact O-N 3.08Å; A484-H487 PolarHBondContact O-N 3.1Å; A484-H487 VanDerWaalsContact O-N 3.13Å; A484-Y488 HydrophobicContact CB-CE2 4.39Å; A484-Y488 WeakPolarHBondContact O-CD2 3.4Å; A484-Y488 PolarHBondContact O-N 3.21Å
485	L	94.1	Very high	93.9	Very high	108 Å²	108	39.1 Å²	39.1	57%	0.565	20%	0.203	S	C	*	.	H	α-helix	trans	-62.1	-41.6	176.3	-70.1	174.3	0	0	0	111.9	L481 I482 H487 Y488 G489	L481-L485 HydrophobicContact CG-CD1 4.3Å; L481-L485 WeakPolarHBondContact O-CG 3.49Å; L481-L485 PolarHBondContact O-N 3.45Å; I482-L485 PolarHBondContact O-N 3.3Å; L485-H487 VanDerWaalsContact C-N 3.28Å; L485-H487 PolarHBondContact O-N 2.92Å; L485-Y488 PolarHBondContact O-N 2.79Å; L485-G489 PolarHBondContact O-N 3.41Å
486	V	92.5	Very high	94.1	Very high	37 Å²	37	43 Å²	43	22%	0.224	22%	0.224	C	C	.	.	H	α-helix	trans	-60.2	-39.6	173.5	170.7	0	0	0	0	110.8	C321 I482 A483 A484 G490	C321-V486 HydrophobicContact CB-CG1 4.25Å; C321-V486 PolarHBondContact SG-O 3.17Å; I482-V486 HydrophobicContact CG2-CG2 4.3Å; I482-V486 VanDerWaalsContact O-CG2 3.31Å; I482-V486 WeakPolarHBondContact O-CG2 3.19Å; I482-V486 PolarHBondContact O-N 3.43Å; A483-V486 PolarHBondContact O-N 3.2Å; A484-V486 VanDerWaalsContact C-N 3.34Å; A484-V486 PolarHBondContact O-N 3.08Å; V486-G490 PolarHBondContact O-N 3.28Å
487	H	92.3	Very high	94.2	Very high	0 Å²	0	46.4 Å²	46.4	0%	0	24%	0.239	C	C	.	.	H	α-helix	trans	-69	-46.3	177.4	-79.7	54.1	0	0	0	112.5	C321 T325 E396 A397 A483 A484 L485 G489 G490 V491	C321-H487 PolarHBondContact O-CE1 2.88Å; C321-H487 PolarHBondContact O-NE2 3.45Å; T325-H487 WeakPolarHBondContact CB-CE1 3.46Å; T325-H487 WeakPolarHBondContact CB-NE2 3.33Å; T325-H487 PolarHBondContact OG1-CE1 3.03Å; T325-H487 PolarHBondContact OG1-ND1 3.36Å; T325-H487 PolarHBondContact OG1-NE2 3.01Å; E396-H487 IonicContact OE2-CD2 2.7Å; A397-H487 HydrophobicContact CB-CB 3.64Å; A483-H487 PolarHBondContact O-N 3.24Å; A483-H487 PolarHBondContact O-ND1 3.33Å; A484-H487 PolarHBondContact O-N 3.1Å; A484-H487 VanDerWaalsContact O-N 3.13Å; L485-H487 VanDerWaalsContact C-N 3.28Å; L485-H487 PolarHBondContact O-N 2.92Å; H487-G489 VanDerWaalsContact C-N 3.32Å; H487-G489 PolarHBondContact O-N 3.34Å; H487-G490 PolarHBondContact O-N 3.17Å; H487-V491 WeakPolarHBondContact O-CB 3.39Å; H487-V491 VanDerWaalsContact O-CG2 3.3Å; H487-V491 WeakPolarHBondContact O-CG2 3.28Å; H487-V491 PolarHBondContact O-N 3.4Å
488	Y	95.4	Very high	94.2	Very high	73 Å²	73	45 Å²	45	29%	0.286	23%	0.234	S	C	.	.	H	α-helix	trans	-61.2	-42.3	176.4	-71.4	-55.8	0	0	0	111.9	A397 T398 L401 A484 L485 G490 V491 I492	A397-Y488 HydrophobicContact CB-CD1 4.15Å; A397-Y488 HydrophobicContact CB-CD2 4.29Å; A397-Y488 HydrophobicContact CB-CE1 3.83Å; A397-Y488 HydrophobicContact CB-CE2 3.99Å; A397-Y488 HydrophobicContact CB-CG 4.36Å; T398-Y488 WeakPolarHBondContact CA-OH 3.49Å; T398-Y488 HydrophobicContact CG2-CE1 4.4Å; T398-Y488 WeakPolarHBondContact CG2-OH 3.38Å; T398-Y488 PolarHBondContact N-OH 3.45Å; L401-Y488 HydrophobicContact CD1-CE2 4.09Å; A484-Y488 HydrophobicContact CB-CE2 4.39Å; A484-Y488 WeakPolarHBondContact O-CD2 3.4Å; A484-Y488 PolarHBondContact O-N 3.21Å; L485-Y488 PolarHBondContact O-N 2.79Å; Y488-G490 VanDerWaalsContact C-N 3.35Å; Y488-G490 PolarHBondContact O-N 2.98Å; Y488-V491 PolarHBondContact O-N 3.11Å; Y488-I492 WeakPolarHBondContact O-CB 3.48Å; Y488-I492 WeakPolarHBondContact O-CD1 3.18Å; Y488-I492 WeakPolarHBondContact O-CG1 3.37Å; Y488-I492 PolarHBondContact O-N 3.33Å
489	G	95.2	Very high	94.2	Very high	38 Å²	38	39.1 Å²	39.1	39%	0.392	21%	0.214	S	C	.	.	H	α-helix	trans	-57.8	-46.7	174.1	0	0	0	0	0	112.1	L485 H487 I492 F493	L485-G489 PolarHBondContact O-N 3.41Å; H487-G489 VanDerWaalsContact C-N 3.32Å; H487-G489 PolarHBondContact O-N 3.34Å; G489-I492 PolarHBondContact O-N 3.19Å; G489-F493 WeakPolarHBondContact O-CB 3.33Å; G489-F493 PolarHBondContact O-N 2.9Å
490	G	94.6	Very high	94	Very high	2 Å²	2	39.2 Å²	39.2	2%	0.021	22%	0.216	C	C	.	.	H	α-helix	trans	-63.2	-41.6	176.3	0	0	0	0	0	113.6	V486 H487 Y488 Y494	V486-G490 PolarHBondContact O-N 3.28Å; H487-G490 PolarHBondContact O-N 3.17Å; Y488-G490 VanDerWaalsContact C-N 3.35Å; Y488-G490 PolarHBondContact O-N 2.98Å; G490-Y494 VanDerWaalsContact O-CB 3.29Å; G490-Y494 WeakPolarHBondContact O-CB 3.44Å; G490-Y494 PolarHBondContact O-N 3.5Å
491	V	95.6	Very high	93.8	Very high	19 Å²	19	45.4 Å²	45.4	12%	0.115	25%	0.245	C	C	.	.	H	α-helix	trans	-63.5	-47.1	176.9	166.5	0	0	0	0	111.3	C390 F393 H487 Y488 Y494 A495	C390-V491 HydrophobicContact CB-CG1 3.81Å; F393-V491 HydrophobicContact CB-CG2 3.35Å; F393-V491 HydrophobicContact CD2-CG2 4.46Å; F393-V491 HydrophobicContact CG-CG2 4.44Å; H487-V491 WeakPolarHBondContact O-CB 3.39Å; H487-V491 VanDerWaalsContact O-CG2 3.3Å; H487-V491 WeakPolarHBondContact O-CG2 3.28Å; H487-V491 PolarHBondContact O-N 3.4Å; Y488-V491 PolarHBondContact O-N 3.11Å; V491-Y494 PolarHBondContact O-N 2.94Å; V491-A495 VanDerWaalsContact O-CB 3.23Å; V491-A495 WeakPolarHBondContact O-CB 3.35Å; V491-A495 PolarHBondContact O-N 3Å
492	I	96.1	Very high	93.5	Very high	101 Å²	101	47 Å²	47	52%	0.518	25%	0.25	S	C	.	.	H	α-helix	trans	-61.7	-47.5	179.3	-68.6	164.1	0	0	0	109.8	Y488 G489 Y494 A495 I496	Y488-I492 WeakPolarHBondContact O-CB 3.48Å; Y488-I492 WeakPolarHBondContact O-CD1 3.18Å; Y488-I492 WeakPolarHBondContact O-CG1 3.37Å; Y488-I492 PolarHBondContact O-N 3.33Å; G489-I492 PolarHBondContact O-N 3.19Å; I492-Y494 PolarHBondContact O-N 3.3Å; I492-A495 PolarHBondContact O-N 2.65Å; I492-I496 HydrophobicContact CG2-CD1 3.89Å; I492-I496 VanDerWaalsContact O-CG1 3.31Å; I492-I496 WeakPolarHBondContact O-CG1 3.39Å; I492-I496 PolarHBondContact O-N 3.28Å; I492-I496 VanDerWaalsContact O-N 3.16Å
493	F	96.5	Very high	93.3	Very high	63 Å²	63	45.4 Å²	45.4	28%	0.276	24%	0.241	S	C	.	.	H	α-helix	trans	-61.6	-44.8	178.9	-168	-95.2	0	0	0	111.8	A314 V317 G489 I496 F497	A314-F493 HydrophobicContact CB-CD1 4.43Å; A314-F493 HydrophobicContact CB-CE1 4.35Å; V317-F493 HydrophobicContact CB-CD1 3.97Å; V317-F493 HydrophobicContact CB-CE1 4.38Å; V317-F493 HydrophobicContact CG1-CB 4.39Å; V317-F493 HydrophobicContact CG1-CD1 4.14Å; V317-F493 HydrophobicContact CG1-CG 4.46Å; V317-F493 HydrophobicContact CG2-CD1 3.97Å; V317-F493 HydrophobicContact CG2-CE1 3.97Å; G489-F493 WeakPolarHBondContact O-CB 3.33Å; G489-F493 PolarHBondContact O-N 2.9Å; F493-I496 PolarHBondContact O-N 3.41Å; F493-F497 HydrophobicContact CD1-CD2 4.18Å; F493-F497 AromaticContact CD2-CD2 3.6Å; F493-F497 HydrophobicContact CD2-CD2 3.6Å; F493-F497 AromaticContact CD2-CE2 3.65Å; F493-F497 HydrophobicContact CD2-CE2 3.65Å; F493-F497 HydrophobicContact CE1-CD2 4.07Å; F493-F497 AromaticContact CE2-CD2 3.47Å; F493-F497 HydrophobicContact CE2-CD2 3.47Å; F493-F497 VanDerWaalsContact CE2-CD2 3.47Å; F493-F497 AromaticContact CE2-CE2 3.5Å; F493-F497 HydrophobicContact CE2-CE2 3.5Å; F493-F497 VanDerWaalsContact CE2-CE2 3.5Å; F493-F497 AromaticContact CG-CD2 3.96Å; F493-F497 HydrophobicContact CG-CD2 3.96Å; F493-F497 HydrophobicContact CG-CE2 4.42Å; F493-F497 AromaticContact CZ-CD2 3.72Å; F493-F497 HydrophobicContact CZ-CD2 3.72Å; F493-F497 HydrophobicContact CZ-CE2 4.16Å; F493-F497 HydrophobicContact CZ-CG 4.44Å; F493-F497 VanDerWaalsContact O-CD2 3.31Å; F493-F497 WeakPolarHBondContact O-CD2 3.22Å; F493-F497 PolarHBondContact O-N 3.08Å
494	Y	95.8	Very high	92.9	Very high	0 Å²	0	50.7 Å²	50.7	0%	0	28%	0.275	C	S	.	.	H	α-helix	trans	-65.5	-41.1	177.3	-166.8	-91.7	0	0	0	112.5	A314 I315 A318 N389 F430 N433 G490 V491 I492 I496 A498	A314-Y494 HydrophobicContact CB-CD2 4.04Å; A314-Y494 WeakPolarHBondContact O-CD2 3.43Å; I315-Y494 HydrophobicContact CG1-CE2 4.22Å; A318-Y494 HydrophobicContact CB-CD2 3.72Å; A318-Y494 HydrophobicContact CB-CE2 4.17Å; A318-Y494 HydrophobicContact CB-CG 4.47Å; N389-Y494 HydrophobicContact CB-CD1 3.89Å; N389-Y494 HydrophobicContact CB-CE1 3.6Å; N389-Y494 WeakPolarHBondContact ND2-CD1 3.06Å; N389-Y494 WeakPolarHBondContact ND2-CD2 3.35Å; N389-Y494 VanDerWaalsContact ND2-CE1 3.26Å; N389-Y494 WeakPolarHBondContact ND2-CE1 3.45Å; F430-Y494 WeakPolarHBondContact CA-OH 3.33Å; F430-Y494 HydrophobicContact CB-CE2 3.86Å; N433-Y494 PolarHBondContact ND2-OH 3.13Å; G490-Y494 VanDerWaalsContact O-CB 3.29Å; G490-Y494 WeakPolarHBondContact O-CB 3.44Å; G490-Y494 PolarHBondContact O-N 3.5Å; V491-Y494 PolarHBondContact O-N 2.94Å; I492-Y494 PolarHBondContact O-N 3.3Å; Y494-I496 VanDerWaalsContact C-N 3.26Å; Y494-I496 PolarHBondContact O-N 3.06Å; Y494-A498 HydrophobicContact CD1-CB 3.73Å; Y494-A498 HydrophobicContact CD2-CB 3.97Å; Y494-A498 HydrophobicContact CE1-CB 3.57Å; Y494-A498 HydrophobicContact CE2-CB 3.81Å; Y494-A498 HydrophobicContact CG-CB 3.94Å; Y494-A498 WeakPolarHBondContact O-CB 3.33Å; Y494-A498 PolarHBondContact O-N 3.31Å
495	A	94.6	Very high	92.5	Very high	40 Å²	40	52.3 Å²	52.3	33%	0.331	28%	0.281	S	S	.	.	H	α-helix	trans	-59.7	-38.3	179.1	0	0	0	0	0	112	K386 V491 I492	K386-A495 VanDerWaalsContact CE-O 3.22Å; K386-A495 WeakPolarHBondContact CE-O 3.36Å; K386-A495 PolarHBondContact NZ-O 3.27Å; V491-A495 VanDerWaalsContact O-CB 3.23Å; V491-A495 WeakPolarHBondContact O-CB 3.35Å; V491-A495 PolarHBondContact O-N 3Å; I492-A495 PolarHBondContact O-N 2.65Å
496	I	95.7	Very high	91.8	Very high	106 Å²	106	47.2 Å²	47.2	54%	0.544	26%	0.255	S	S	.	.	H	α-helix	trans	-77.2	-53.3	-179.4	-61.9	166.5	0	0	0	110.5	I492 F493 Y494	I492-I496 HydrophobicContact CG2-CD1 3.89Å; I492-I496 VanDerWaalsContact O-CG1 3.31Å; I492-I496 WeakPolarHBondContact O-CG1 3.39Å; I492-I496 PolarHBondContact O-N 3.28Å; I492-I496 VanDerWaalsContact O-N 3.16Å; F493-I496 PolarHBondContact O-N 3.41Å; Y494-I496 VanDerWaalsContact C-N 3.26Å; Y494-I496 PolarHBondContact O-N 3.06Å
497	F	95.1	Very high	90.6	Very high	77 Å²	77	48.7 Å²	48.7	34%	0.338	26%	0.261	S	S	.	.	H	α-helix	trans	-100.7	-10.1	-163.7	-61.2	-66.7	0	0	0	115.9	M310 A314 F493	M310-F497 HydrophobicContact CB-CB 4.28Å; M310-F497 HydrophobicContact CB-CD1 4.22Å; M310-F497 HydrophobicContact CG-CD1 4.42Å; A314-F497 HydrophobicContact CB-CB 4.16Å; F493-F497 HydrophobicContact CD1-CD2 4.18Å; F493-F497 AromaticContact CD2-CD2 3.6Å; F493-F497 HydrophobicContact CD2-CD2 3.6Å; F493-F497 AromaticContact CD2-CE2 3.65Å; F493-F497 HydrophobicContact CD2-CE2 3.65Å; F493-F497 HydrophobicContact CE1-CD2 4.07Å; F493-F497 AromaticContact CE2-CD2 3.47Å; F493-F497 HydrophobicContact CE2-CD2 3.47Å; F493-F497 VanDerWaalsContact CE2-CD2 3.47Å; F493-F497 AromaticContact CE2-CE2 3.5Å; F493-F497 HydrophobicContact CE2-CE2 3.5Å; F493-F497 VanDerWaalsContact CE2-CE2 3.5Å; F493-F497 AromaticContact CG-CD2 3.96Å; F493-F497 HydrophobicContact CG-CD2 3.96Å; F493-F497 HydrophobicContact CG-CE2 4.42Å; F493-F497 AromaticContact CZ-CD2 3.72Å; F493-F497 HydrophobicContact CZ-CD2 3.72Å; F493-F497 HydrophobicContact CZ-CE2 4.16Å; F493-F497 HydrophobicContact CZ-CG 4.44Å; F493-F497 VanDerWaalsContact O-CD2 3.31Å; F493-F497 WeakPolarHBondContact O-CD2 3.22Å; F493-F497 PolarHBondContact O-N 3.08Å
498	A	93.4	Very high	89.1	Confident	7 Å²	7	50.4 Å²	50.4	6%	0.058	27%	0.272	C	S	.	.			trans	-69.7	139.7	179.4	0	0	0	0	0	111.9	A314 K386 Y494	A314-A498 HydrophobicContact CB-CB 4.28Å; K386-A498 WeakPolarHBondContact CE-O 3.31Å; K386-A498 HydrophobicContact CG-CB 4.43Å; K386-A498 PolarHBondContact NZ-O 3.06Å; Y494-A498 HydrophobicContact CD1-CB 3.73Å; Y494-A498 HydrophobicContact CD2-CB 3.97Å; Y494-A498 HydrophobicContact CE1-CB 3.57Å; Y494-A498 HydrophobicContact CE2-CB 3.81Å; Y494-A498 HydrophobicContact CG-CB 3.94Å; Y494-A498 WeakPolarHBondContact O-CB 3.33Å; Y494-A498 PolarHBondContact O-N 3.31Å
499	S	93	Very high	86.9	Confident	23 Å²	23	55.7 Å²	55.7	16%	0.161	30%	0.3	C	S	.	.			trans	-125.1	147.8	166.7	-177	0	0	0	0	109	N433 I437 E501	N433-S499 PolarHBondContact ND2-O 3.2Å; N433-S499 VanDerWaalsContact ND2-O 3.08Å; N433-S499 PolarHBondContact OD1-O 3.47Å; I437-S499 WeakPolarHBondContact CG1-O 3.48Å; S499-E501 PolarHBondContact OG-N 3.37Å; S499-E501 VanDerWaalsContact OG-N 3.1Å
500	G	87.8	Confident	84.4	Confident	8 Å²	8	61.3 Å²	61.3	8%	0.082	32%	0.316	C	S	.	.			trans	-111.5	14.7	168.4	0	0	0	0	0	112.2	T382	T382-G500 WeakPolarHBondContact OG1-CA 3.47Å; T382-G500 PolarHBondContact OG1-N 3.3Å
501	E	88.9	Confident	81.8	Confident	137 Å²	137	68.1 Å²	68.1	64%	0.64	36%	0.357	S	S	*	.	S	Bend	trans	-97	146.2	173.5	-67.3	177.8	-175	0	0	110.6	S499 Q503	S499-E501 PolarHBondContact OG-N 3.37Å; S499-E501 VanDerWaalsContact OG-N 3.1Å; E501-Q503 PolarHBondContact O-N 3.02Å; E501-Q503 PolarHBondContact O-NE2 3.31Å; E501-Q503 VanDerWaalsContact O-NE2 3.08Å
502	K	87.8	Confident	78.7	Confident	84 Å²	84	68.4 Å²	68.4	37%	0.365	36%	0.36	S	S	.	.	P	Polyproline II helix	trans	-59.8	132.2	178.4	-170.4	-177.8	178.8	-167	0	109.8	I437 A506 D507	I437-K502 WeakPolarHBondContact O-CA 3.35Å; K502-A506 HydrophobicContact CG-CB 4.14Å; K502-D507 VanDerWaalsContact CE-OD1 3.31Å; K502-D507 WeakPolarHBondContact CE-OD1 3.27Å; K502-D507 WeakPolarHBondContact CE-OD2 3.29Å; K502-D507 IonicContact NZ-OD1 2.9Å; K502-D507 PolarHBondContact NZ-OD1 3.15Å; K502-D507 IonicContact NZ-OD2 3.41Å; K502-D507 PolarHBondContact NZ-OD2 3.43Å
503	Q	88.4	Confident	76	Confident	29 Å²	29	72.4 Å²	72.4	14%	0.136	38%	0.377	C	S	.	.	P	Polyproline II helix	trans	-83	149.6	-176.6	-62.9	-64.1	-68.1	0	0	111.8	I437 E501 W505 A506	I437-Q503 HydrophobicContact CB-CG 4.32Å; I437-Q503 HydrophobicContact CG2-CB 4.31Å; I437-Q503 HydrophobicContact CG2-CG 3.29Å; I437-Q503 PolarHBondContact O-N 3.49Å; E501-Q503 PolarHBondContact O-N 3.02Å; E501-Q503 PolarHBondContact O-NE2 3.31Å; E501-Q503 VanDerWaalsContact O-NE2 3.08Å; Q503-W505 HydrophobicContact CB-CD2 3.99Å; Q503-W505 VanDerWaalsContact CB-CE2 3.44Å; Q503-W505 HydrophobicContact CB-CG 4.35Å; Q503-W505 HydrophobicContact CB-CH2 4.4Å; Q503-W505 HydrophobicContact CB-CZ2 3.7Å; Q503-W505 HydrophobicContact CG-CZ2 3.73Å; Q503-W505 PolarHBondContact O-N 3.02Å; Q503-W505 VanDerWaalsContact O-N 3.16Å; Q503-A506 WeakPolarHBondContact O-CB 3.32Å; Q503-A506 PolarHBondContact O-N 3.19Å
504	P	84.9	Confident	73.3	Confident	111 Å²	111	78.4 Å²	78.4	72%	0.721	41%	0.405	S	S	*	.	G	3₁₀ helix	trans	-57.9	-34.2	-177.1	-26.3	34.2	0	0	0	114.2	A506	P504-A506 PolarHBondContact O-N 2.64Å
505	W	83.8	Confident	70.5	Confident	36 Å²	36	86.8 Å²	86.8	14%	0.136	44%	0.442	C	S	.	.	G	3₁₀ helix	trans	-78.8	-5.5	178.8	51.9	-102.2	0	0	0	113.9	K305 F306 V312 I437 A438 Y441 L445 Q503	K305-W505 HydrophobicContact CB-CB 3.96Å; K305-W505 HydrophobicContact CB-CG 3.91Å; K305-W505 HydrophobicContact CG-CB 4.25Å; F306-W505 HydrophobicContact CD1-CD2 4.24Å; F306-W505 AromaticContact CD1-CE3 3.71Å; F306-W505 HydrophobicContact CD1-CE3 3.71Å; F306-W505 AromaticContact CD1-CH2 3.89Å; F306-W505 HydrophobicContact CD1-CH2 3.89Å; F306-W505 HydrophobicContact CD1-CZ2 4.39Å; F306-W505 AromaticContact CD1-CZ3 3.51Å; F306-W505 HydrophobicContact CD1-CZ3 3.51Å; F306-W505 HydrophobicContact CE1-CD2 4.37Å; F306-W505 AromaticContact CE1-CE3 3.45Å; F306-W505 HydrophobicContact CE1-CE3 3.45Å; F306-W505 VanDerWaalsContact CE1-CE3 3.45Å; F306-W505 HydrophobicContact CE1-CH2 4.11Å; F306-W505 AromaticContact CE1-CZ3 3.29Å; F306-W505 HydrophobicContact CE1-CZ3 3.29Å; F306-W505 HydrophobicContact CZ-CZ3 4.44Å; V312-W505 HydrophobicContact CG2-CH2 4.28Å; V312-W505 HydrophobicContact CG2-CZ2 3.95Å; I437-W505 HydrophobicContact CG2-CH2 3.98Å; I437-W505 HydrophobicContact CG2-CZ2 4Å; A438-W505 HydrophobicContact CB-CE3 4.42Å; A438-W505 HydrophobicContact CB-CH2 3.56Å; A438-W505 HydrophobicContact CB-CZ3 3.36Å; Y441-W505 HydrophobicContact CD2-CE3 4.33Å; Y441-W505 HydrophobicContact CD2-CZ3 4.13Å; L445-W505 HydrophobicContact CD1-CH2 3.92Å; L445-W505 HydrophobicContact CD1-CZ3 4.44Å; Q503-W505 HydrophobicContact CB-CD2 3.99Å; Q503-W505 VanDerWaalsContact CB-CE2 3.44Å; Q503-W505 HydrophobicContact CB-CG 4.35Å; Q503-W505 HydrophobicContact CB-CH2 4.4Å; Q503-W505 HydrophobicContact CB-CZ2 3.7Å; Q503-W505 HydrophobicContact CG-CZ2 3.73Å; Q503-W505 PolarHBondContact O-N 3.02Å; Q503-W505 VanDerWaalsContact O-N 3.16Å
506	A	79.3	Confident	67.7	Low	1 Å²	1	90.3 Å²	90.3	1%	0.008	46%	0.463	C	S	.	.	G	3₁₀ helix	trans	-82.8	-23.3	176	0	0	0	0	0	111.8	A438 K502 Q503 P504	A438-A506 HydrophobicContact CB-CB 3.7Å; K502-A506 HydrophobicContact CG-CB 4.14Å; Q503-A506 WeakPolarHBondContact O-CB 3.32Å; Q503-A506 PolarHBondContact O-N 3.19Å; P504-A506 PolarHBondContact O-N 2.64Å
507	D	69	Low	64.8	Low	68 Å²	68	87.7 Å²	87.7	36%	0.364	46%	0.462	S	S	.	.	S	Bend	trans	-76.8	142.6	168.3	-82.8	-52.2	0	0	0	110.5	K502 E509	K502-D507 VanDerWaalsContact CE-OD1 3.31Å; K502-D507 WeakPolarHBondContact CE-OD1 3.27Å; K502-D507 WeakPolarHBondContact CE-OD2 3.29Å; K502-D507 IonicContact NZ-OD1 2.9Å; K502-D507 PolarHBondContact NZ-OD1 3.15Å; K502-D507 IonicContact NZ-OD2 3.41Å; K502-D507 PolarHBondContact NZ-OD2 3.43Å; D507-E509 PolarHBondContact O-N 3.41Å
508	P	60	Low	62.2	Low	35 Å²	35	92.9 Å²	92.9	23%	0.227	49%	0.485	C	S	.	.	P	Polyproline II helix	trans	-57.3	130.2	163.2	25	-22.2	0	0	0	105.6	R440 E510	R440-P508 VanDerWaalsContact NH1-N 3.18Å; P508-E510 PolarHBondContact O-N 3.17Å
509	E	50.3	Low	59.5	Low	185 Å²	185	100 Å²	100	86%	0.864	52%	0.52	S	S	*	.	P	Polyproline II helix	trans	-46.1	117.1	168.2	-77.7	175	160.4	0	0	106.4	D507 T511	D507-E509 PolarHBondContact O-N 3.41Å; E509-T511 PolarHBondContact O-N 2.8Å; E509-T511 VanDerWaalsContact O-N 3.1Å
510	E	41.9	Very low	56.9	Low	156 Å²	156	106 Å²	106	73%	0.729	55%	0.546	S	S	*	.	P	Polyproline II helix	trans	-52	125.5	179.1	-68.5	174.6	159.8	0	0	106.3	P508 S512	P508-E510 PolarHBondContact O-N 3.17Å; E510-S512 PolarHBondContact O-N 2.86Å
511	T	39.4	Very low	54.5	Low	144 Å²	144	113.8 Å²	113.8	88%	0.883	58%	0.579	S	S	*	*				-48.2	72.8	126.8	42.4	0	0	0	0	107.5	E509 E513	E509-T511 PolarHBondContact O-N 2.8Å; E509-T511 VanDerWaalsContact O-N 3.1Å; T511-E513 PolarHBondContact O-N 3.32Å
512	S	31.8	Very low	52.3	Low	25 Å²	25	113.8 Å²	113.8	18%	0.175	58%	0.584	C	S	.	*			trans	-75.2	114.9	164	67.2	0	0	0	0	103.3	E510 E514 K515	E510-S512 PolarHBondContact O-N 2.86Å; S512-E514 PolarHBondContact O-N 3.39Å; S512-E514 VanDerWaalsContact O-N 3.07Å; S512-K515 PolarHBondContact O-N 3.43Å; S512-K515 WeakPolarHBondContact OG-CB 3.12Å; S512-K515 WeakPolarHBondContact OG-CG 3.33Å; S512-K515 PolarHBondContact OG-N 2.68Å
513	E	39.3	Very low	49.9	Very low	186 Å²	186	118.3 Å²	118.3	87%	0.869	61%	0.606	S	S	*	*	G	3₁₀ helix	trans	-54.7	-18.7	164.2	-69.2	-178.1	152.8	0	0	110.3	T511 K515 C516	T511-E513 PolarHBondContact O-N 3.32Å; E513-K515 VanDerWaalsContact C-N 3.32Å; E513-K515 PolarHBondContact O-N 3.2Å; E513-C516 WeakPolarHBondContact O-CB 3.37Å; E513-C516 PolarHBondContact O-N 3.18Å
514	E	39.1	Very low	47.5	Very low	188 Å²	188	123.4 Å²	123.4	88%	0.879	63%	0.634	S	S	*	*	G	3₁₀ helix	trans	-68.6	-16	168.9	-74.1	-169.5	148	0	0	115.7	S512	S512-E514 PolarHBondContact O-N 3.39Å; S512-E514 VanDerWaalsContact O-N 3.07Å
515	K	37.6	Very low	45.2	Very low	176 Å²	176	124.1 Å²	124.1	77%	0.765	63%	0.632	S	S	*	*	G	3₁₀ helix	trans	-105.6	15.6	169.9	-77	-174.3	178.7	179.8	0	113.3	S512 E513 G517	S512-K515 PolarHBondContact O-N 3.43Å; S512-K515 WeakPolarHBondContact OG-CB 3.12Å; S512-K515 WeakPolarHBondContact OG-CG 3.33Å; S512-K515 PolarHBondContact OG-N 2.68Å; E513-K515 VanDerWaalsContact C-N 3.32Å; E513-K515 PolarHBondContact O-N 3.2Å; K515-G517 PolarHBondContact O-N 3.12Å; K515-G517 VanDerWaalsContact O-N 3.09Å
516	C	35.3	Very low	43.2	Very low	115 Å²	115	130.9 Å²	130.9	78%	0.777	67%	0.665	S	S	*	*			trans	-80.3	36.2	163.4	-129	0	0	0	0	111.7	E513	E513-C516 WeakPolarHBondContact O-CB 3.37Å; E513-C516 PolarHBondContact O-N 3.18Å
517	G	35.8	Very low	41.3	Very low	51 Å²	51	138.6 Å²	138.6	53%	0.526	70%	0.701	S	S	.	*	S	Bend	trans	-101.9	98.1	172.4	0	0	0	0	0	109.3	K515	K515-G517 PolarHBondContact O-N 3.12Å; K515-G517 VanDerWaalsContact O-N 3.09Å
518	F	39.1	Very low	39.9	Very low	186 Å²	186	140 Å²	140	82%	0.816	71%	0.712	S	S	*	*			trans	47	86.2	169.5	-54.9	-79.8	0	0	0	115.4	H520	F518-H520 VanDerWaalsContact C-N 3.27Å; F518-H520 PolarHBondContact O-N 3.37Å
519	I	37.1	Very low	38.7	Very low	155 Å²	155	140.9 Å²	140.9	80%	0.795	73%	0.727	S	S	*	*			trans	-64.4	97.1	153.7	-57.1	173.5	0	0	0	105.8
520	H	37.5	Very low	38.1	Very low	151 Å²	151	139 Å²	139	70%	0.699	72%	0.723	S	S	*	*			trans	-69.6	140.1	162.7	-87.5	-72.9	0	0	0	108.5	F518 D522	F518-H520 VanDerWaalsContact C-N 3.27Å; F518-H520 PolarHBondContact O-N 3.37Å; H520-D522 PolarHBondContact O-N 2.93Å
521	E	39.3	Very low	37.8	Very low	170 Å²	170	138.7 Å²	138.7	79%	0.794	73%	0.725	S	S	*	*	G	3₁₀ helix	trans	-54.9	15.4	-165.6	-81.5	166.2	136	0	0	119
522	D	41.1	Very low	37.6	Very low	137 Å²	137	137.8 Å²	137.8	73%	0.733	72%	0.719	S	S	*	*	G	3₁₀ helix	trans	-92	-7.1	-167.5	-72.5	-16.5	0	0	0	115.7	H520	H520-D522 PolarHBondContact O-N 2.93Å
523	E	38.9	Very low	37.6	Very low	179 Å²	179	144.6 Å²	144.6	84%	0.836	75%	0.748	S	S	*	*	G	3₁₀ helix	trans	-98.4	-2.2	-178.3	-86.5	-172.8	167.9	0	0	115.4
524	L	37.3	Very low	37.3	Very low	136 Å²	136	142.9 Å²	142.9	71%	0.712	75%	0.745	S	S	*	*	S	Bend	trans	-94.2	-9.5	175.6	-76.7	166.9	0	0	0	114
525	D	37.2	Very low	36.8	Very low	126 Å²	126	145 Å²	145	67%	0.674	75%	0.747	S	S	*	*	S	Bend	trans	-84.6	-16.3	179.9	-86.1	-6.3	0	0	0	113.6
526	E	40.6	Very low	36.3	Very low	178 Å²	178	144.6 Å²	144.6	83%	0.832	75%	0.751	S	S	*	*	S	Bend	trans	-82.7	-19.6	177.4	-74.8	-166.5	163.1	0	0	113.9
527	E	40.3	Very low	35.9	Very low	163 Å²	163	146.5 Å²	146.5	76%	0.762	75%	0.753	S	S	*	*	S	Bend	trans	-89.6	-10.4	178.8	-92.3	-166.8	161.2	0	0	114.6
528	T	39.1	Very low	35.5	Very low	99 Å²	99	155 Å²	155	61%	0.607	77%	0.771	S	S	*	*	S	Bend	trans	-93.2	-9	176.4	37.8	0	0	0	0	114.2
529	G	35.5	Very low	34.9	Very low	52 Å²	52	149.1 Å²	149.1	54%	0.536	76%	0.763	S	S	.	*	S	Bend	trans	-77.3	-22.8	-178.4	0	0	0	0	0	116.2
530	D	36.2	Very low	34.3	Very low	145 Å²	145	148 Å²	148	78%	0.775	76%	0.764	S	S	*	*	S	Bend	trans	-103.9	0.7	-166.5	-112.6	-3.4	0	0	0	115.1
531	I	37.4	Very low	33.7	Very low	150 Å²	150	146.4 Å²	146.4	77%	0.769	77%	0.765	S	S	*	*	S	Bend	trans	-99.3	-6.8	-176.1	-57.1	178.1	0	0	0	113.1
532	T	34.7	Very low	33	Very low	125 Å²	125	147.6 Å²	147.6	77%	0.767	77%	0.768	S	S	*	*	S	Bend	trans	-106.5	11.6	-176.6	47.4	0	0	0	0	115.7
533	Q	31.8	Very low	32.3	Very low	168 Å²	168	145.9 Å²	145.9	79%	0.785	77%	0.766	S	S	*	*			trans	-102.3	38.4	-174.9	-133.3	-180	41.9	0	0	115.3
534	N	31.8	Very low	31.7	Very low	151 Å²	151	148.2 Å²	148.2	81%	0.807	77%	0.769	S	S	*	*	S	Bend	trans	-150.9	57.4	172.8	-103.8	-22.3	0	0	0	113.9
535	Y	28.4	Very low	31.2	Very low	232 Å²	232	145.2 Å²	145.2	91%	0.91	77%	0.771	S	S	*	*			trans	-158.2	96.3	153.3	-96.2	-77	0	0	0	109.1
536	I	27.6	Very low	30.7	Very low	167 Å²	167	143.5 Å²	143.5	86%	0.856	77%	0.774	S	S	*	*			trans	-113.9	105.7	161.9	-63.6	179.2	0	0	0	106.9
537	N	27.8	Very low	30.1	Very low	155 Å²	155	141 Å²	141	83%	0.829	77%	0.771	S	S	*	*			trans	-106.9	134.6	163.8	-148.3	7.8	0	0	0	108.1
538	Y	27.8	Very low	29.5	Very low	229 Å²	229	139.2 Å²	139.2	90%	0.898	77%	0.772	S	S	*	*			trans	-62.6	140.1	177.9	-95.1	-104.7	0	0	0	111.6
539	G	25.5	Very low	28.8	Very low	63 Å²	63	142.1 Å²	142.1	65%	0.649	78%	0.778	S	S	*	*			trans	151	92.4	159.6	0	0	0	0	0	116.9
540	T	24.7	Very low	28.3	Very low	133 Å²	133	146.8 Å²	146.8	82%	0.816	79%	0.786	S	S	*	*			trans	35.7	136.1	135.8	44.2	0	0	0	0	122.9
541	T	24.8	Very low	27.9	Very low	117 Å²	117	147.4 Å²	147.4	72%	0.718	79%	0.79	S	S	*	*			trans	93.8	109.4	138.7	31.9	0	0	0	0	122.6
542	K	25.1	Very low	27.3	Very low	195 Å²	195	144.1 Å²	144.1	85%	0.848	79%	0.792	S	S	*	*				62.1	113.8	125.8	-72.9	-178.3	178.8	-178.2	0	122.4
543	S	25.8	Very low	26.8	Very low	101 Å²	101	141.8 Å²	141.8	71%	0.706	79%	0.794	S	S	*	*				68.7	158.7	110.5	-151.5	0	0	0	0	122.9
544	Y	26.2	Very low	26.8	Very low	228 Å²	228	145.6 Å²	145.6	89%	0.894	80%	0.801	S	S	*	*			trans	86.3	133.5	-179.4	-64.1	-87.3	0	0	0	115.5
545	G	26.7	Very low	27	Very low	72 Å²	72	144.3 Å²	144.3	74%	0.742	80%	0.8	S	S	*	*			cis	147	117.7	7.9	0	0	0	0	0	109.6
546	A	27.8	Very low	27.2	Very low	91 Å²	91	141.1 Å²	141.1	75%	0.752	80%	0.799	S	S	*	*			trans	34.2	147	152.1	0	0	0	0	0	125.5
547	T	27	Very low	27.2	Very low	126 Å²	126	136.2 Å²	136.2	77%	0.773	79%	0.79	S	S	*	*			trans	91.9	109.2	139.2	42.7	0	0	0	0	123.6
548	T	27	Very low	27.4	Very low	125 Å²	125	140.7 Å²	140.7	77%	0.767	80%	0.796	S	S	*	*				49.9	129.1	125.6	56.7	0	0	0	0	124.6
549	Q	25.8	Very low	27.6	Very low	160 Å²	160	138.3 Å²	138.3	75%	0.748	79%	0.793	S	S	*	*			trans	91.5	124.7	135.4	-125.9	178.6	-22.2	0	0	122.4
550	E	24.7	Very low	28	Very low	149 Å²	149	145.1 Å²	145.1	70%	0.696	80%	0.804	S	S	*	*			trans	79.6	122.8	139.3	-98.6	171.7	-139.3	0	0	124.3
551	N	27.9	Very low	28.4	Very low	159 Å²	159	148.5 Å²	148.5	85%	0.85	81%	0.808	S	S	*	*			trans	55.8	123.9	142.2	-83.9	-16	0	0	0	122
552	G	24.8	Very low	28.9	Very low	80 Å²	80	151.6 Å²	151.6	83%	0.825	81%	0.814	S	S	*	*			trans	164.3	101.2	149.6	0	0	0	0	0	116.5
553	G	24.9	Very low	29.3	Very low	77 Å²	77	151.3 Å²	151.3	79%	0.794	82%	0.816	S	S	*	*			trans	86.7	96.4	139.5	0	0	0	0	0	118.9
554	W	31	Very low	29.6	Very low	248 Å²	248	156.5 Å²	156.5	94%	0.939	83%	0.826	S	S	*	*	P	Polyproline II helix	trans	-78.4	134.9	154.7	-77	77.2	0	0	0	110
555	P	35.9	Very low	30.1	Very low	123 Å²	123	152 Å²	152	80%	0.799	82%	0.822	S	S	*	*	P	Polyproline II helix	trans	-82.2	133.3	162.5	10	6.1	0	0	0	111
556	N	31.6	Very low	30.3	Very low	165 Å²	165	157.7 Å²	157.7	88%	0.882	83%	0.829	S	S	*	*	P	Polyproline II helix	trans	-68.2	154.8	178.5	-77.9	-38.3	0	0	0	115.1
557	G	28.9	Very low	30.7	Very low	65 Å²	65	162.2 Å²	162.2	67%	0.67	84%	0.835	S	S	*	*			trans	94.9	118.7	158.3	0	0	0	0	0	112.5
558	W	30.8	Very low	31.1	Very low	249 Å²	249	159.6 Å²	159.6	94%	0.943	83%	0.833	S	S	*	*				-152	162.4	51.8	-88.3	62.4	0	0	0	112.1
559	E	32.9	Very low	31.3	Very low	179 Å²	179	158.8 Å²	158.8	84%	0.836	84%	0.839	S	S	*	*	P	Polyproline II helix	trans	-65.4	146.4	-156.1	-63.9	162.6	145.6	0	0	117.4
560	K	33.9	Very low	31.6	Very low	205 Å²	205	159.9 Å²	159.9	89%	0.891	84%	0.844	S	S	*	*	P	Polyproline II helix	trans	-67	127.9	162.1	-75.1	178.8	175.1	-179.8	0	109.6
561	K	32.9	Very low	32	Very low	205 Å²	205	160.1 Å²	160.1	89%	0.891	85%	0.85	S	S	*	*	P	Polyproline II helix	trans	-103.5	120.5	156.2	-116.4	-178.1	179	-179.5	0	108.2
562	E	35.9	Very low	32.2	Very low	182 Å²	182	156.5 Å²	156.5	85%	0.85	84%	0.842	S	S	*	*	P	Polyproline II helix	trans	-65.1	130.2	174.3	-65.9	172.8	155.3	0	0	109.9
563	E	32.7	Very low	32.6	Very low	188 Å²	188	163.1 Å²	163.1	88%	0.879	84%	0.844	S	S	*	*	P	Polyproline II helix	trans	-81	131.2	166.3	-82.6	-178.1	155.1	0	0	109.4	V565	E563-V565 PolarHBondContact O-N 2.62Å
564	F	33.3	Very low	32.9	Very low	211 Å²	211	165.2 Å²	165.2	93%	0.925	84%	0.842	S	S	*	*	P	Polyproline II helix	trans	-67.1	116.9	175.5	-87.8	-97.1	0	0	0	110.4
565	V	35.3	Very low	32.9	Very low	134 Å²	134	163.9 Å²	163.9	81%	0.812	84%	0.838	S	S	*	*	P	Polyproline II helix	trans	-74.9	124.6	164.1	177.9	0	0	0	0	107.8	E563 E567	E563-V565 PolarHBondContact O-N 2.62Å; V565-E567 PolarHBondContact O-N 3.47Å
566	Q	31.6	Very low	32.7	Very low	190 Å²	190	166.6 Å²	166.6	89%	0.888	84%	0.837	S	S	*	*			trans	-75.8	112	178.2	-158	164.7	3.7	0	0	109.2
567	E	35.3	Very low	32.7	Very low	186 Å²	186	166.3 Å²	166.3	87%	0.869	84%	0.836	S	S	*	*			trans	-69.5	141.4	172.2	-81.7	-176.7	153.3	0	0	111.1	V565	V565-E567 PolarHBondContact O-N 3.47Å
568	G	35.8	Very low	32.9	Very low	72 Å²	72	171.4 Å²	171.4	74%	0.742	84%	0.842	S	S	*	*			trans	-64.1	138.4	-179.8	0	0	0	0	0	112.4	Q570	G568-Q570 PolarHBondContact O-N 3.17Å; G568-Q570 VanDerWaalsContact O-N 3.14Å
569	A	31.9	Very low	32.9	Very low	107 Å²	107	166.5 Å²	166.5	88%	0.884	83%	0.834	S	S	*	*			trans	-66.8	111.3	177.7	0	0	0	0	0	111.2
570	Q	31.2	Very low	32.9	Very low	183 Å²	183	164.4 Å²	164.4	86%	0.855	83%	0.829	S	S	*	*			trans	-129	119	153.3	-83.5	-173.4	-15.4	0	0	107.2	G568	G568-Q570 PolarHBondContact O-N 3.17Å; G568-Q570 VanDerWaalsContact O-N 3.14Å
571	D	33.4	Very low	33.1	Very low	155 Å²	155	164.8 Å²	164.8	83%	0.829	83%	0.826	S	S	*	*			trans	-135.6	121.6	156.3	-103	-25.7	0	0	0	110.2
572	A	31.7	Very low	33.3	Very low	83 Å²	83	164 Å²	164	69%	0.686	85%	0.846	S	S	*	*			trans	-85.2	120.7	174.6	0	0	0	0	0	109.1
573	Y	34.3	Very low	33.2	Very low	218 Å²	218	163.1 Å²	163.1	86%	0.855	85%	0.846	S	S	*	*			trans	-106.2	96.4	153.4	-84.4	-83.2	0	0	0	108.4
574	T	29.8	Very low	33.2	Very low	122 Å²	122	161.7 Å²	161.7	75%	0.748	84%	0.844	S	S	*	*			trans	-84.2	111	165.3	-40.6	0	0	0	0	107.9
575	Y	31.8	Very low	33.2	Very low	219 Å²	219	159 Å²	159	86%	0.859	84%	0.84	S	S	*	*			trans	-103.6	118.2	152.5	-114.8	-88.2	0	0	0	107
576	K	32.1	Very low	33.1	Very low	181 Å²	181	160.5 Å²	160.5	79%	0.787	84%	0.841	S	S	*	*			trans	-71.9	135.3	160.1	-92.2	179.8	169.8	-179.9	0	107.7
577	D	30.8	Very low	33.1	Very low	159 Å²	159	158.6 Å²	158.6	85%	0.85	84%	0.838	S	S	*	*				-155	138.4	125.4	-95.4	-27.2	0	0	0	110.2
578	Q	32.8	Very low	33	Very low	171 Å²	171	156.8 Å²	156.8	80%	0.799	84%	0.836	S	S	*	*			trans	-73.4	148.3	176	-61.6	167.4	-95.9	0	0	109.7
579	D	31.5	Very low	32.8	Very low	147 Å²	147	162.9 Å²	162.9	79%	0.786	84%	0.843	S	S	*	*				173.5	150.2	107.2	-90	-22.5	0	0	0	112.4
580	D	33.9	Very low	32.9	Very low	135 Å²	135	167.2 Å²	167.2	72%	0.722	84%	0.84	S	S	*	*			trans	-43.7	152.4	174	-73.8	-49.6	0	0	0	115.1
581	Y	36.6	Very low	33	Very low	213 Å²	213	165.8 Å²	165.8	84%	0.835	84%	0.839	S	S	*	*				174.3	118.8	109.7	-94.5	-73.7	0	0	0	110.6
582	S	37.4	Very low	33	Very low	187 Å²	187	166.8 Å²	166.8	100%	1.308	84%	0.84	S	S	*	*			trans	62.5	0	145.5	-59.2	0	0	0	0	121

Retrieved 582 of 582 residues in 111.5 ms (Link to these results)

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