A0A061IPH4_CRIGR Loading...

Proteinase-activated receptor 4

Receptor for activated thrombin or trypsin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation.

AlphaFold DB , UniProt , Accession A0A061IPH4, Species CRIGR (Cricetulus griseus, Chinese hamster), Gene F2rl3, Length 394 aa.

Structure Viewer

Loading PAE data...

(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	34.1	Very low	38.7	Very low	235 Å²	235	137.4 Å²	137.4	100%	1.158	73%	0.725	S	S	*	*				0	75.3	0	-76.7	141	57.2	0	0	108.3
2	S	32.9	Very low	38.5	Very low	97 Å²	97	131.8 Å²	131.8	68%	0.678	73%	0.725	S	S	*	*			trans	-138.3	33.1	-165.7	-47.4	0	0	0	0	113.5
3	W	31	Very low	38.4	Very low	235 Å²	235	134.7 Å²	134.7	89%	0.89	74%	0.738	S	S	*	*	S	Bend	trans	-106.2	-8.6	178.9	-67.1	101	0	0	0	113.7
4	L	38.6	Very low	37.8	Very low	161 Å²	161	133.2 Å²	133.2	84%	0.843	74%	0.742	S	S	*	*	S	Bend	trans	-90.8	-8.8	-175.8	-73.8	165.4	0	0	0	114.4
5	L	40.5	Very low	37.4	Very low	143 Å²	143	135.7 Å²	135.7	75%	0.749	75%	0.752	S	S	*	*	T	Hydrogen-bonded Turn	trans	-90.5	-4.3	-174.9	-69.8	170.8	0	0	0	114.7
6	L	40	Very low	37	Very low	122 Å²	122	133.2 Å²	133.2	64%	0.639	75%	0.754	S	S	*	*	T	Hydrogen-bonded Turn	trans	-84.8	-11.9	177.6	-77.5	163.3	0	0	0	113.8
7	C	41.4	Very low	36.5	Very low	79 Å²	79	137.2 Å²	137.2	53%	0.534	77%	0.765	S	S	.	*	S	Bend	trans	-74.6	-41.7	-175.4	-148.9	0	0	0	0	114.8	L9 V10	C7-L9 VanDerWaalsContact C-N 3.34Å; C7-L9 PolarHBondContact O-N 3.44Å; C7-V10 PolarHBondContact O-N 3.42Å
8	P	40.2	Very low	36.1	Very low	88 Å²	88	133.8 Å²	133.8	57%	0.571	77%	0.766	S	S	*	*	G	3₁₀ helix	trans	-64.7	-34.2	-175.2	-23.1	34.6	0	0	0	114.2	V10 L11	P8-V10 PolarHBondContact O-N 3.35Å; P8-L11 PolarHBondContact O-N 3.14Å
9	L	37.8	Very low	35.5	Very low	159 Å²	159	134.2 Å²	134.2	83%	0.832	77%	0.771	S	S	*	*	G	3₁₀ helix	trans	-70	-16.5	-179.4	-87.5	156.2	0	0	0	113.9	C7	C7-L9 VanDerWaalsContact C-N 3.34Å; C7-L9 PolarHBondContact O-N 3.44Å
10	V	45.2	Very low	35	Very low	88 Å²	88	136.8 Å²	136.8	53%	0.533	78%	0.776	S	S	.	*	G	3₁₀ helix	trans	-95.2	-13.8	178.2	-177.7	0	0	0	0	111.8	C7 P8 P253	C7-V10 PolarHBondContact O-N 3.42Å; P8-V10 PolarHBondContact O-N 3.35Å; V10-P253 HydrophobicContact CG1-CB 4.13Å
11	L	43.6	Very low	34.6	Very low	104 Å²	104	136.9 Å²	136.9	55%	0.545	78%	0.78	S	S	.	*	S	Bend	trans	-97.5	10.4	-171.8	-74.7	168.9	0	0	0	115.1	P8 L13	P8-L11 PolarHBondContact O-N 3.14Å; L11-L13 PolarHBondContact O-N 3.47Å
12	G	36.4	Very low	34.4	Very low	71 Å²	71	131.1 Å²	131.1	73%	0.732	76%	0.76	S	S	*	*			trans	65.3	10.9	161.8	0	0	0	0	0	117.6	S14	G12-S14 VanDerWaalsContact C-N 3.29Å; G12-S14 PolarHBondContact O-N 3.17Å
13	L	37.3	Very low	34.1	Very low	169 Å²	169	131.7 Å²	131.7	89%	0.885	76%	0.764	S	S	*	*			trans	-77.4	76.8	176	-78.5	165.1	0	0	0	111.1	L11 L15	L11-L13 PolarHBondContact O-N 3.47Å; L13-L15 PolarHBondContact O-N 3.48Å
14	S	29.8	Very low	34	Very low	114 Å²	114	127.4 Å²	127.4	80%	0.797	76%	0.757	S	S	*	*			trans	-83.2	108.6	170	-160.5	0	0	0	0	110.1	G12	G12-S14 VanDerWaalsContact C-N 3.29Å; G12-S14 PolarHBondContact O-N 3.17Å
15	L	32.1	Very low	33.5	Very low	171 Å²	171	131 Å²	131	90%	0.895	76%	0.761	S	S	*	*			trans	-67.7	141.6	156.4	-92.6	159.5	0	0	0	108.4	L13	L13-L15 PolarHBondContact O-N 3.48Å
16	A	30.7	Very low	32.9	Very low	95 Å²	95	130.6 Å²	130.6	79%	0.785	76%	0.759	S	S	*	*			trans	-76.7	140.2	-170.5	0	0	0	0	0	113
17	E	29.1	Very low	32.5	Very low	202 Å²	202	132.2 Å²	132.2	94%	0.944	77%	0.769	S	S	*	*			trans	-143.7	131.2	145.3	-114.7	175.5	132.4	0	0	108
18	G	29.2	Very low	31.8	Very low	75 Å²	75	132.5 Å²	132.5	77%	0.773	79%	0.785	S	S	*	*			trans	-113.2	136.7	-173.5	0	0	0	0	0	111.7
19	T	24.7	Very low	31.2	Very low	142 Å²	142	137.2 Å²	137.2	87%	0.871	80%	0.799	S	S	*	*			trans	-143.5	117.1	164.8	-33.9	0	0	0	0	109.7
20	Q	25.2	Very low	30.9	Very low	185 Å²	185	133.8 Å²	133.8	86%	0.864	79%	0.789	S	S	*	*			trans	-79.3	143.6	166.1	-69.3	173	-39.1	0	0	109.6
21	T	25.9	Very low	31	Very low	139 Å²	139	135.5 Å²	135.5	85%	0.853	80%	0.802	S	S	*	*			trans	-165.2	149.2	132.2	18	0	0	0	0	111
22	P	31.8	Very low	30.3	Very low	115 Å²	115	134.5 Å²	134.5	75%	0.747	82%	0.816	S	S	*	*			trans	-109.9	165.2	-177.5	40.6	-33.1	0	0	0	114.3
23	S	26.7	Very low	29.9	Very low	108 Å²	108	135.1 Å²	135.1	76%	0.755	82%	0.823	S	S	*	*			trans	-149	115.8	159.5	56.3	0	0	0	0	107.2
24	I	27.3	Very low	29.5	Very low	145 Å²	145	130.6 Å²	130.6	74%	0.744	82%	0.817	S	S	*	*				52.2	105.1	67.1	-57.5	179.8	0	0	0	111.5
25	Y	29.2	Very low	29.5	Very low	236 Å²	236	134.7 Å²	134.7	93%	0.925	82%	0.823	S	S	*	*			trans	-147.8	146.7	131.4	-108.5	-76.7	0	0	0	108.8
26	D	27.9	Very low	29.4	Very low	135 Å²	135	135.8 Å²	135.8	72%	0.722	82%	0.824	S	S	*	*			trans	-122.7	-175.9	-166	-146.8	-26.1	0	0	0	110.8
27	D	30.5	Very low	29.4	Very low	157 Å²	157	134.6 Å²	134.6	84%	0.84	82%	0.821	S	S	*	*			trans	77.8	131	162.3	-63.8	-52.1	0	0	0	120.2
28	G	26.7	Very low	29.3	Very low	85 Å²	85	131.2 Å²	131.2	88%	0.876	81%	0.814	S	S	*	*			trans	171.8	37	173.8	0	0	0	0	0	119.2
29	E	27.8	Very low	29.3	Very low	186 Å²	186	134.6 Å²	134.6	87%	0.869	82%	0.819	S	S	*	*			trans	-100.3	164	173.9	-120.1	-162.3	72.4	0	0	111.3
30	S	32.6	Very low	29.4	Very low	87 Å²	87	131 Å²	131	61%	0.608	81%	0.81	S	S	*	*			cis	-147.7	-138.4	11.8	-157.4	0	0	0	0	112.3
31	P	47.5	Very low	29.8	Very low	125 Å²	125	128.4 Å²	128.4	81%	0.812	81%	0.81	S	S	*	*			trans	-133.1	-171	-137.6	41.7	-18.3	0	0	0	117.4
32	G	28.1	Very low	30	Very low	82 Å²	82	128.6 Å²	128.6	85%	0.845	81%	0.811	S	S	*	*			trans	121.3	147.8	165.2	0	0	0	0	0	113.9
33	G	27.8	Very low	30	Very low	84 Å²	84	128.5 Å²	128.5	87%	0.866	82%	0.82	S	S	*	*			cis	-165	165	-4.1	0	0	0	0	0	109.1
34	G	27.9	Very low	30	Very low	74 Å²	74	126.4 Å²	126.4	76%	0.763	82%	0.816	S	S	*	*			trans	-105.1	175.5	-165.6	0	0	0	0	0	117.5
35	H	30.4	Very low	30.2	Very low	200 Å²	200	127.6 Å²	127.6	93%	0.926	82%	0.822	S	S	*	*			trans	-162.7	151.5	156.9	-114.7	-71.1	0	0	0	112.6
36	E	30.7	Very low	30	Very low	194 Å²	194	126 Å²	126	91%	0.907	82%	0.82	S	S	*	*			trans	-86.6	163.3	-177.9	-70	169.7	75.7	0	0	115.2
37	G	29.7	Very low	30	Very low	71 Å²	71	126.7 Å²	126.7	73%	0.732	82%	0.819	S	S	*	*			trans	172.8	59.1	171.7	0	0	0	0	0	121.1
38	T	27.9	Very low	29.9	Very low	131 Å²	131	124.7 Å²	124.7	80%	0.804	82%	0.817	S	S	*	*			trans	45	112.3	136.2	-45.4	0	0	0	0	124.2
39	V	28.7	Very low	30	Very low	145 Å²	145	129.1 Å²	129.1	88%	0.879	81%	0.813	S	S	*	*			trans	70.8	127	141.4	177.5	0	0	0	0	123
40	G	27.2	Very low	30	Very low	66 Å²	66	124.3 Å²	124.3	68%	0.68	80%	0.8	S	S	*	*			trans	154.2	117.8	155.3	0	0	0	0	0	114.1
41	P	34.6	Very low	30.1	Very low	131 Å²	131	125.9 Å²	125.9	85%	0.851	81%	0.808	S	S	*	*			trans	-96	134.4	-170.8	35.1	-32.6	0	0	0	114.2
42	T	28.1	Very low	29.7	Very low	143 Å²	143	126 Å²	126	88%	0.877	81%	0.806	S	S	*	*			trans	-129.4	121.1	157.6	40.8	0	0	0	0	110.4	G44	T42-G44 PolarHBondContact O-N 2.92Å
43	A	33.2	Very low	29.9	Very low	114 Å²	114	129.7 Å²	129.7	94%	0.942	80%	0.801	S	S	*	*			trans	-71.5	88.5	177.6	0	0	0	0	0	110.5
44	G	26.4	Very low	30.4	Very low	64 Å²	64	131.1 Å²	131.1	66%	0.66	79%	0.789	S	S	*	*			trans	-89.3	111.9	166.5	0	0	0	0	0	110.1	T42 K46	T42-G44 PolarHBondContact O-N 2.92Å; G44-K46 VanDerWaalsContact C-N 3.31Å; G44-K46 PolarHBondContact O-N 3.22Å
45	L	30.8	Very low	31.1	Very low	169 Å²	169	132.5 Å²	132.5	89%	0.885	78%	0.775	S	S	*	*			trans	-66.5	84.3	178.5	-161.6	82.5	0	0	0	110.5	E47	L45-E47 PolarHBondContact O-N 3.45Å; L45-E47 VanDerWaalsContact O-N 3.07Å
46	K	25.4	Very low	31.5	Very low	202 Å²	202	126.2 Å²	126.2	88%	0.878	75%	0.752	S	S	*	*			trans	-75.9	92.6	169	-86.5	-173.7	174.7	178.8	0	109	G44 S48	G44-K46 VanDerWaalsContact C-N 3.31Å; G44-K46 PolarHBondContact O-N 3.22Å; K46-S48 PolarHBondContact O-N 3.16Å; K46-S48 VanDerWaalsContact O-N 3.13Å
47	E	29.1	Very low	32.4	Very low	150 Å²	150	122.1 Å²	122.1	70%	0.701	73%	0.728	S	S	*	*			trans	-50.1	119.3	154.6	-74.8	-171	133	0	0	108.4	L45 K49	L45-E47 PolarHBondContact O-N 3.45Å; L45-E47 VanDerWaalsContact O-N 3.07Å; E47-K49 PolarHBondContact O-N 2.69Å
48	S	26.6	Very low	33.3	Very low	115 Å²	115	118.9 Å²	118.9	80%	0.804	69%	0.694	S	S	*	*			trans	-70.5	82	166.2	-175	0	0	0	0	108.1	K46 S50	K46-S48 PolarHBondContact O-N 3.16Å; K46-S48 VanDerWaalsContact O-N 3.13Å; S48-S50 PolarHBondContact O-N 3.22Å
49	K	29.7	Very low	34.5	Very low	178 Å²	178	113 Å²	113	77%	0.774	66%	0.658	S	S	*	*			trans	-65.7	92.7	160.5	-92.7	-176.7	177.5	172.5	0	107.2	E47	E47-K49 PolarHBondContact O-N 2.69Å
50	S	28.8	Very low	36	Very low	86 Å²	86	107 Å²	107	60%	0.601	62%	0.622	S	S	*	*			trans	-46.6	139.5	159.9	36.9	0	0	0	0	109	S48 V52	S48-S50 PolarHBondContact O-N 3.22Å; S50-V52 PolarHBondContact O-N 3.46Å
51	P	33.1	Very low	37.8	Very low	120 Å²	120	103.9 Å²	103.9	78%	0.779	59%	0.59	S	S	*	*			trans	-61.7	116.8	-179.9	25.3	-32.9	0	0	0	108.1	Q53	P51-Q53 PolarHBondContact O-N 3.31Å
52	V	39.2	Very low	40	Very low	128 Å²	128	103.9 Å²	103.9	78%	0.776	58%	0.577	S	S	*	*			trans	-61.6	103	173.8	175.8	0	0	0	0	106.7	S50 L54	S50-V52 PolarHBondContact O-N 3.46Å; V52-L54 PolarHBondContact O-N 2.78Å; V52-L54 VanDerWaalsContact O-N 3.12Å
53	Q	33.9	Very low	42.6	Very low	158 Å²	158	101.4 Å²	101.4	74%	0.738	55%	0.554	S	S	*	*	P	Polyproline II helix	trans	-59.9	118.9	175	-81.4	-173.2	-15.2	0	0	108.4	P51 H55	P51-Q53 PolarHBondContact O-N 3.31Å; Q53-H55 PolarHBondContact O-CE1 3.45Å; Q53-H55 PolarHBondContact O-N 2.95Å; Q53-H55 PolarHBondContact O-ND1 3.02Å
54	L	37.4	Very low	45	Very low	115 Å²	115	97.2 Å²	97.2	60%	0.602	52%	0.517	S	S	*	.	P	Polyproline II helix	trans	-68.9	118.1	170.4	-83.6	81.7	0	0	0	108.4	V52	V52-L54 PolarHBondContact O-N 2.78Å; V52-L54 VanDerWaalsContact O-N 3.12Å
55	H	41.9	Very low	47.5	Very low	102 Å²	102	98.6 Å²	98.6	47%	0.472	52%	0.523	S	S	.	.	P	Polyproline II helix	trans	-83.3	130.3	-177.4	-69.4	52.7	0	0	0	110.7	Q53	Q53-H55 PolarHBondContact O-CE1 3.45Å; Q53-H55 PolarHBondContact O-N 2.95Å; Q53-H55 PolarHBondContact O-ND1 3.02Å
56	P	39.7	Very low	49.9	Very low	68 Å²	68	99 Å²	99	44%	0.442	53%	0.526	S	S	.	.	P	Polyproline II helix	trans	-69	153.3	167.3	29.4	-31.7	0	0	0	110.6
57	R	50.1	Low	52.8	Low	108 Å²	108	92.1 Å²	92.1	41%	0.408	50%	0.499	S	S	.	.			trans	-126.1	158.8	-168.1	-57.1	-170.1	-175.5	168.4	3.5	112.8	P322 G326	R57-P322 PolarHBondContact NE-O 3.17Å; R57-P322 PolarHBondContact NH1-O 2.78Å; R57-P322 PolarHBondContact NH2-O 2.84Å; R57-G326 WeakPolarHBondContact CD-O 3.45Å; R57-G326 PolarHBondContact NH1-O 3.01Å
58	G	48.4	Very low	55.5	Low	3 Å²	3	88.8 Å²	88.8	3%	0.031	49%	0.492	C	S	.	.	S	Bend	trans	77.6	-170.8	-153.8	0	0	0	0	0	111	P60	G58-P60 WeakPolarHBondContact O-CD 3.44Å
59	F	51.8	Low	58.4	Low	8 Å²	8	86.5 Å²	86.5	4%	0.035	47%	0.47	C	S	.	.			trans	-110.5	63.4	169.2	-61.7	-86	0	0	0	112.4	G61 L73 S77 L81 D240 A241 L242 Y329	F59-G61 VanDerWaalsContact C-N 3.26Å; F59-G61 PolarHBondContact O-N 3.47Å; F59-L73 HydrophobicContact CB-CD2 4.07Å; F59-L73 HydrophobicContact CD1-CB 4.01Å; F59-L73 HydrophobicContact CD1-CD1 3.45Å; F59-L73 VanDerWaalsContact CD1-CD1 3.45Å; F59-L73 HydrophobicContact CD1-CD2 3.87Å; F59-L73 HydrophobicContact CD1-CG 3.95Å; F59-L73 HydrophobicContact CE1-CB 4.37Å; F59-L73 HydrophobicContact CE1-CD1 3.87Å; F59-L73 HydrophobicContact CG-CD1 4.33Å; F59-L73 HydrophobicContact CG-CD2 4.45Å; F59-S77 VanDerWaalsContact CE1-O 3.3Å; F59-S77 WeakPolarHBondContact CE1-O 3.48Å; F59-S77 VanDerWaalsContact CZ-C 3.49Å; F59-S77 WeakPolarHBondContact CZ-O 3.38Å; F59-L81 HydrophobicContact CD2-CD1 4.43Å; F59-L81 HydrophobicContact CE1-CB 4.02Å; F59-L81 HydrophobicContact CE1-CD1 4.27Å; F59-L81 HydrophobicContact CE2-CB 4.38Å; F59-L81 HydrophobicContact CE2-CD1 3.82Å; F59-L81 HydrophobicContact CZ-CB 3.53Å; F59-L81 HydrophobicContact CZ-CD1 3.72Å; F59-L81 HydrophobicContact CZ-CG 4.14Å; F59-D240 WeakPolarHBondContact CB-O 3.12Å; F59-D240 VanDerWaalsContact CD2-O 3.3Å; F59-D240 WeakPolarHBondContact CD2-O 3.25Å; F59-A241 HydrophobicContact CB-CB 3.7Å; F59-A241 HydrophobicContact CG-CB 4.3Å; F59-L242 PolarHBondContact O-N 3.24Å; F59-L242 VanDerWaalsContact O-N 3.1Å; F59-L242 VanDerWaalsContact O-O 3.06Å; F59-Y329 HydrophobicContact CD2-CD1 4.45Å; F59-Y329 AromaticContact CD2-CD2 3.6Å; F59-Y329 HydrophobicContact CD2-CD2 3.6Å; F59-Y329 HydrophobicContact CD2-CE1 4.47Å; F59-Y329 AromaticContact CD2-CE2 3.6Å; F59-Y329 HydrophobicContact CD2-CE2 3.6Å; F59-Y329 HydrophobicContact CD2-CG 4.03Å; F59-Y329 AromaticContact CE2-CD1 3.64Å; F59-Y329 HydrophobicContact CE2-CD1 3.64Å; F59-Y329 AromaticContact CE2-CD2 3.6Å; F59-Y329 HydrophobicContact CE2-CD2 3.6Å; F59-Y329 AromaticContact CE2-CE1 3.59Å; F59-Y329 HydrophobicContact CE2-CE1 3.59Å; F59-Y329 AromaticContact CE2-CE2 3.54Å; F59-Y329 HydrophobicContact CE2-CE2 3.54Å; F59-Y329 AromaticContact CE2-CG 3.63Å; F59-Y329 HydrophobicContact CE2-CG 3.63Å; F59-Y329 AromaticContact CE2-CZ 3.53Å; F59-Y329 HydrophobicContact CZ-CE1 4.4Å
60	P	60.9	Low	61.2	Low	19 Å²	19	78.8 Å²	78.8	12%	0.123	44%	0.438	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-70.2	93.3	156	30.6	-27.2	0	0	0	107.7	G58 L242 L244	G58-P60 WeakPolarHBondContact O-CD 3.44Å; P60-L242 CarbonylContact C-O 3.35Å; P60-L242 WeakPolarHBondContact CA-O 3.2Å; P60-L244 HydrophobicContact CB-CB 3.76Å; P60-L244 HydrophobicContact CB-CD1 3.56Å; P60-L244 HydrophobicContact CB-CG 4.12Å; P60-L244 HydrophobicContact CG-CD1 4.22Å
61	G	65.3	Low	63.9	Low	1 Å²	1	74.7 Å²	74.7	1%	0.01	41%	0.409	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-67.6	146.2	177.8	0	0	0	0	0	111.3	F59 L242 L244	F59-G61 VanDerWaalsContact C-N 3.26Å; F59-G61 PolarHBondContact O-N 3.47Å; G61-L242 PolarHBondContact N-O 3.16Å; G61-L244 PolarHBondContact O-N 2.64Å
62	K	79.9	Confident	66.4	Low	131 Å²	131	73.8 Å²	73.8	57%	0.57	40%	0.395	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-99.7	139.1	165.9	-65.3	-178.2	-179.3	179.6	0	108	L71 E72	K62-L71 CarbonylContact O-C 3.51Å; K62-L71 WeakPolarHBondContact O-CA 3.4Å; K62-E72 PolarHBondContact N-O 2.89Å; K62-E72 PolarHBondContact O-N 3.21Å
63	F	83.7	Confident	68.3	Low	90 Å²	90	68.2 Å²	68.2	40%	0.395	36%	0.361	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-64.1	142	172.4	-65.4	-67	0	0	0	110.5	S68 T70 L71 F228 P243	F63-S68 WeakPolarHBondContact CD1-O 3.36Å; F63-S68 WeakPolarHBondContact CE1-O 3.29Å; F63-T70 WeakPolarHBondContact CA-O 3.41Å; F63-L71 HydrophobicContact CD1-CD2 3.63Å; F63-L71 HydrophobicContact CE1-CD2 3.76Å; F63-L71 HydrophobicContact CG-CD2 4.23Å; F63-L71 HydrophobicContact CZ-CD2 4.46Å; F63-F228 HydrophobicContact CE1-CD1 4.19Å; F63-F228 AromaticContact CE1-CE1 3.83Å; F63-F228 HydrophobicContact CE1-CE1 3.83Å; F63-F228 HydrophobicContact CZ-CE1 4.3Å; F63-P243 HydrophobicContact CE1-CG 4.17Å; F63-P243 HydrophobicContact CE2-CB 3.89Å; F63-P243 HydrophobicContact CE2-CG 4.26Å; F63-P243 HydrophobicContact CZ-CB 3.71Å; F63-P243 HydrophobicContact CZ-CG 3.55Å
64	C	82.8	Confident	70.6	Confident	26 Å²	26	62.4 Å²	62.4	18%	0.176	34%	0.337	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-60.4	149.9	167	-78.4	0	0	0	0	110	N66 D67 T70 E72	C64-N66 PolarHBondContact O-N 2.97Å; C64-N66 VanDerWaalsContact O-N 3.12Å; C64-D67 HydrophobicContact CB-CB 4.12Å; C64-D67 PolarHBondContact O-N 3.08Å; C64-D67 VanDerWaalsContact O-N 3.08Å; C64-T70 PolarHBondContact N-O 2.88Å; C64-T70 VanDerWaalsContact N-O 3.17Å; C64-E72 WeakPolarHBondContact SG-CG 3.37Å; C64-E72 PolarHBondContact SG-OE1 2.88Å
65	A	79.6	Confident	72.6	Confident	94 Å²	94	60.8 Å²	60.8	78%	0.777	34%	0.34	S	S	*	.	T	Hydrogen-bonded Turn	trans	-58.9	120.6	174.3	0	0	0	0	0	110.1	D67	A65-D67 VanDerWaalsContact C-N 3.32Å; A65-D67 PolarHBondContact O-N 3.49Å
66	N	80.5	Confident	74.4	Confident	177 Å²	177	59.1 Å²	59.1	95%	0.947	34%	0.34	S	S	*	.	T	Hydrogen-bonded Turn	trans	67.7	12.7	-176.2	-51.5	-27.6	0	0	0	116.8	C64	C64-N66 PolarHBondContact O-N 2.97Å; C64-N66 VanDerWaalsContact O-N 3.12Å
67	D	86.6	Confident	76.2	Confident	58 Å²	58	56 Å²	56	31%	0.31	32%	0.319	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-133.9	112.2	173.9	-176.9	3.8	0	0	0	111.9	C64 A65 D69 T70	C64-D67 HydrophobicContact CB-CB 4.12Å; C64-D67 PolarHBondContact O-N 3.08Å; C64-D67 VanDerWaalsContact O-N 3.08Å; A65-D67 VanDerWaalsContact C-N 3.32Å; A65-D67 PolarHBondContact O-N 3.49Å; D67-D69 WeakPolarHBondContact OD1-CA 3.49Å; D67-D69 WeakPolarHBondContact OD1-CB 3.45Å; D67-D69 PolarHBondContact OD1-N 2.99Å; D67-T70 WeakPolarHBondContact OD2-CB 3.44Å; D67-T70 PolarHBondContact OD2-OG1 3.21Å
68	S	85.5	Confident	77.8	Confident	79 Å²	79	53.5 Å²	53.5	55%	0.552	31%	0.312	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-87.6	-3.4	178.2	57.4	0	0	0	0	114.3	F63	F63-S68 WeakPolarHBondContact CD1-O 3.36Å; F63-S68 WeakPolarHBondContact CE1-O 3.29Å
69	D	87.5	Confident	79.5	Confident	67 Å²	67	56.8 Å²	56.8	36%	0.358	34%	0.339	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-93	-18.1	175.4	-72.5	-19.7	0	0	0	112.7	D67 R225 F228 R229	D67-D69 WeakPolarHBondContact OD1-CA 3.49Å; D67-D69 WeakPolarHBondContact OD1-CB 3.45Å; D67-D69 PolarHBondContact OD1-N 2.99Å; D69-R225 IonicContact OD1-CZ 3.61Å; D69-R225 IonicContact OD1-NH1 3.82Å; D69-R225 PolarHBondContact OD1-NH1 2.97Å; D69-R225 IonicContact OD1-NH2 3.82Å; D69-R225 PolarHBondContact OD1-NH2 3.49Å; D69-F228 CarbonylContact O-C 3.59Å; D69-F228 WeakPolarHBondContact O-CA 3.47Å; D69-R229 PolarHBondContact O-N 3.35Å
70	T	89.8	Confident	81	Confident	16 Å²	16	58.3 Å²	58.3	10%	0.098	35%	0.347	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-112.8	135	-174.3	-56.1	0	0	0	0	112.2	F63 C64 D67 R229 A231	F63-T70 WeakPolarHBondContact CA-O 3.41Å; C64-T70 PolarHBondContact N-O 2.88Å; C64-T70 VanDerWaalsContact N-O 3.17Å; D67-T70 WeakPolarHBondContact OD2-CB 3.44Å; D67-T70 PolarHBondContact OD2-OG1 3.21Å; T70-R229 WeakPolarHBondContact CA-O 3.4Å; T70-R229 HydrophobicContact CG2-CB 4.28Å; T70-A231 HydrophobicContact CG2-CB 3.9Å
71	L	85.3	Confident	82.2	Confident	0 Å²	0	57.4 Å²	57.4	0%	0	34%	0.341	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-113	129.4	177.7	-67.8	178.9	0	0	0	112.1	K62 F63 L73 F228 R229 A231 A241	K62-L71 CarbonylContact O-C 3.51Å; K62-L71 WeakPolarHBondContact O-CA 3.4Å; F63-L71 HydrophobicContact CD1-CD2 3.63Å; F63-L71 HydrophobicContact CE1-CD2 3.76Å; F63-L71 HydrophobicContact CG-CD2 4.23Å; F63-L71 HydrophobicContact CZ-CD2 4.46Å; L71-L73 HydrophobicContact CB-CD2 4.48Å; L71-F228 HydrophobicContact CB-CB 4.47Å; L71-F228 HydrophobicContact CD1-CB 3.58Å; L71-F228 HydrophobicContact CD1-CD1 4.03Å; L71-F228 HydrophobicContact CD1-CD2 3.71Å; L71-F228 HydrophobicContact CD1-CE2 4.44Å; L71-F228 HydrophobicContact CD1-CG 3.48Å; L71-F228 VanDerWaalsContact CD1-CG 3.48Å; L71-F228 HydrophobicContact CD2-CD1 4.48Å; L71-F228 HydrophobicContact CG-CB 3.74Å; L71-F228 HydrophobicContact CG-CD1 4.01Å; L71-F228 HydrophobicContact CG-CG 3.84Å; L71-R229 PolarHBondContact N-O 2.88Å; L71-A231 WeakPolarHBondContact O-CB 3.18Å; L71-A231 PolarHBondContact O-N 3.5Å; L71-A241 HydrophobicContact CD1-CB 4.35Å
72	E	84.5	Confident	83.3	Confident	101 Å²	101	60.6 Å²	60.6	47%	0.472	36%	0.358	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-84.7	129.5	167.8	-59.7	-174.8	178.1	0	0	110.4	K62 C64 A231	K62-E72 PolarHBondContact N-O 2.89Å; K62-E72 PolarHBondContact O-N 3.21Å; C64-E72 WeakPolarHBondContact SG-CG 3.37Å; C64-E72 PolarHBondContact SG-OE1 2.88Å; E72-A231 HydrophobicContact CB-CB 4.37Å; E72-A231 HydrophobicContact CG-CB 3.78Å
73	L	80	Confident	83.7	Confident	11 Å²	11	55.3 Å²	55.3	6%	0.058	34%	0.34	C	S	.	.			trans	-125.6	141.5	-177.9	-55.9	177.8	0	0	0	109.8	F59 L71 Q78 L81 L230 L237 A241	F59-L73 HydrophobicContact CB-CD2 4.07Å; F59-L73 HydrophobicContact CD1-CB 4.01Å; F59-L73 HydrophobicContact CD1-CD1 3.45Å; F59-L73 VanDerWaalsContact CD1-CD1 3.45Å; F59-L73 HydrophobicContact CD1-CD2 3.87Å; F59-L73 HydrophobicContact CD1-CG 3.95Å; F59-L73 HydrophobicContact CE1-CB 4.37Å; F59-L73 HydrophobicContact CE1-CD1 3.87Å; F59-L73 HydrophobicContact CG-CD1 4.33Å; F59-L73 HydrophobicContact CG-CD2 4.45Å; L71-L73 HydrophobicContact CB-CD2 4.48Å; L73-Q78 HydrophobicContact CB-CG 3.84Å; L73-Q78 PolarHBondContact O-NE2 3.23Å; L73-L81 HydrophobicContact CD1-CD2 4.5Å; L73-L230 HydrophobicContact CB-CD1 4.21Å; L73-L230 HydrophobicContact CD1-CD1 3.45Å; L73-L230 VanDerWaalsContact CD1-CD1 3.45Å; L73-L230 HydrophobicContact CG-CD1 3.85Å; L73-L237 HydrophobicContact CD1-CD1 3.91Å; L73-A241 HydrophobicContact CD1-CB 3.82Å; L73-A241 HydrophobicContact CD2-CB 4.09Å
74	P	80.6	Confident	84.1	Confident	37 Å²	37	58.6 Å²	58.6	24%	0.24	35%	0.35	C	S	.	.			trans	-57.5	145.7	176.8	-22.9	32.9	0	0	0	112.2	S76 S77 Q78	P74-S76 VanDerWaalsContact C-N 3.28Å; P74-S76 PolarHBondContact O-N 3Å; P74-S77 WeakPolarHBondContact O-CA 3.3Å; P74-S77 WeakPolarHBondContact O-CB 3.36Å; P74-S77 PolarHBondContact O-N 2.98Å; P74-Q78 PolarHBondContact O-N 2.85Å
75	A	80.1	Confident	84.5	Confident	80 Å²	80	58.9 Å²	58.9	66%	0.661	35%	0.35	S	S	*	.	H	α-helix	trans	-58.1	-37.1	-175.9	0	0	0	0	0	113.5	S77 Q78 A79	A75-S77 VanDerWaalsContact C-N 3.32Å; A75-S77 PolarHBondContact O-N 3.28Å; A75-Q78 PolarHBondContact O-N 3.04Å; A75-A79 WeakPolarHBondContact O-CB 3.4Å; A75-A79 PolarHBondContact O-N 3.47Å
76	S	78.9	Confident	84.9	Confident	68 Å²	68	54.5 Å²	54.5	48%	0.476	31%	0.313	S	S	.	.	H	α-helix	trans	-60.5	-41.9	173.4	53.4	0	0	0	0	112.3	P74 L80	P74-S76 VanDerWaalsContact C-N 3.28Å; P74-S76 PolarHBondContact O-N 3Å; S76-L80 PolarHBondContact O-N 2.8Å
77	S	78.7	Confident	85.5	Confident	1 Å²	1	47.7 Å²	47.7	1%	0.007	28%	0.278	C	S	.	.	H	α-helix	trans	-68.8	-48.7	178	-43.8	0	0	0	0	109.4	F59 P74 A75 A79 L80 L81	F59-S77 VanDerWaalsContact CE1-O 3.3Å; F59-S77 WeakPolarHBondContact CE1-O 3.48Å; F59-S77 VanDerWaalsContact CZ-C 3.49Å; F59-S77 WeakPolarHBondContact CZ-O 3.38Å; P74-S77 WeakPolarHBondContact O-CA 3.3Å; P74-S77 WeakPolarHBondContact O-CB 3.36Å; P74-S77 PolarHBondContact O-N 2.98Å; A75-S77 VanDerWaalsContact C-N 3.32Å; A75-S77 PolarHBondContact O-N 3.28Å; S77-A79 VanDerWaalsContact C-N 3.29Å; S77-A79 PolarHBondContact O-N 2.99Å; S77-L80 CarbonylContact O-C 3.58Å; S77-L80 WeakPolarHBondContact O-CA 3.41Å; S77-L80 WeakPolarHBondContact O-CB 3.38Å; S77-L80 PolarHBondContact O-N 2.98Å; S77-L81 PolarHBondContact O-N 3.11Å
78	Q	82.4	Confident	85.8	Confident	57 Å²	57	53.8 Å²	53.8	27%	0.266	30%	0.297	S	S	.	.	H	α-helix	trans	-54.6	-43.1	176.9	-64.6	-170.6	24.3	0	0	112.7	L73 P74 A75 L80 L81 L82 L230	L73-Q78 HydrophobicContact CB-CG 3.84Å; L73-Q78 PolarHBondContact O-NE2 3.23Å; P74-Q78 PolarHBondContact O-N 2.85Å; A75-Q78 PolarHBondContact O-N 3.04Å; Q78-L80 PolarHBondContact O-N 2.93Å; Q78-L81 WeakPolarHBondContact O-CB 3.44Å; Q78-L81 PolarHBondContact O-N 3.26Å; Q78-L82 WeakPolarHBondContact O-CG 3.4Å; Q78-L82 PolarHBondContact O-N 3.17Å; Q78-L230 HydrophobicContact CG-CD1 4.27Å
79	A	85.1	Confident	86.2	Confident	71 Å²	71	52.9 Å²	52.9	59%	0.587	29%	0.286	S	S	*	.	H	α-helix	trans	-61.8	-30.9	175.8	0	0	0	0	0	113.1	A75 S77 G83	A75-A79 WeakPolarHBondContact O-CB 3.4Å; A75-A79 PolarHBondContact O-N 3.47Å; S77-A79 VanDerWaalsContact C-N 3.29Å; S77-A79 PolarHBondContact O-N 2.99Å; A79-G83 WeakPolarHBondContact O-CA 3.19Å; A79-G83 PolarHBondContact O-N 2.99Å; A79-G83 VanDerWaalsContact O-N 3.12Å
80	L	84.1	Confident	86.6	Confident	40 Å²	40	49.7 Å²	49.7	21%	0.209	27%	0.268	C	S	.	.	H	α-helix	trans	-78.7	-37.6	175.2	-172.4	62.3	0	0	0	112.5	S76 S77 Q78 G83 D327 Y329	S76-L80 PolarHBondContact O-N 2.8Å; S77-L80 CarbonylContact O-C 3.58Å; S77-L80 WeakPolarHBondContact O-CA 3.41Å; S77-L80 WeakPolarHBondContact O-CB 3.38Å; S77-L80 PolarHBondContact O-N 2.98Å; Q78-L80 PolarHBondContact O-N 2.93Å; L80-G83 PolarHBondContact O-N 3.25Å; L80-D327 HydrophobicContact CD2-CB 4.41Å; L80-D327 VanDerWaalsContact CD2-OD2 3.3Å; L80-D327 WeakPolarHBondContact CD2-OD2 3.5Å; L80-Y329 HydrophobicContact CD2-CD1 3.9Å; L80-Y329 HydrophobicContact CG-CD1 4.02Å
81	L	84.6	Confident	86.9	Confident	0 Å²	0	49.2 Å²	49.2	0%	0	27%	0.266	C	S	.	.	H	α-helix	trans	-57.7	-49	174.6	-165.3	71.7	0	0	0	111.3	F59 L73 S77 Q78 G83 P86 Q150 L230 L237 D240	F59-L81 HydrophobicContact CD2-CD1 4.43Å; F59-L81 HydrophobicContact CE1-CB 4.02Å; F59-L81 HydrophobicContact CE1-CD1 4.27Å; F59-L81 HydrophobicContact CE2-CB 4.38Å; F59-L81 HydrophobicContact CE2-CD1 3.82Å; F59-L81 HydrophobicContact CZ-CB 3.53Å; F59-L81 HydrophobicContact CZ-CD1 3.72Å; F59-L81 HydrophobicContact CZ-CG 4.14Å; L73-L81 HydrophobicContact CD1-CD2 4.5Å; S77-L81 PolarHBondContact O-N 3.11Å; Q78-L81 WeakPolarHBondContact O-CB 3.44Å; Q78-L81 PolarHBondContact O-N 3.26Å; L81-G83 VanDerWaalsContact C-N 3.3Å; L81-P86 WeakPolarHBondContact O-CB 3.41Å; L81-P86 WeakPolarHBondContact O-CG 3.42Å; L81-Q150 HydrophobicContact CG-CG 4.38Å; L81-L230 HydrophobicContact CD2-CD2 4.22Å; L81-L237 HydrophobicContact CD2-CD1 3.8Å; L81-L237 HydrophobicContact CD2-CD2 3.74Å; L81-L237 HydrophobicContact CD2-CG 4.45Å; L81-D240 HydrophobicContact CD1-CB 3.82Å
82	L	88.1	Confident	87.4	Confident	69 Å²	69	52.2 Å²	52.2	36%	0.361	29%	0.29	S	S	.	.	S	Bend	trans	-90.5	1.7	-176	-54.1	-174.8	0	0	0	112.3	Q78 Q150	Q78-L82 WeakPolarHBondContact O-CG 3.4Å; Q78-L82 PolarHBondContact O-N 3.17Å; L82-Q150 HydrophobicContact CD2-CB 4.37Å; L82-Q150 HydrophobicContact CD2-CG 4.06Å
83	G	89.3	Confident	87.9	Confident	19 Å²	19	48.5 Å²	48.5	20%	0.196	27%	0.273	C	S	.	.	S	Bend	trans	-67.6	172.8	179.1	0	0	0	0	0	113.5	A79 L80 L81 I85 P86 T87	A79-G83 WeakPolarHBondContact O-CA 3.19Å; A79-G83 PolarHBondContact O-N 2.99Å; A79-G83 VanDerWaalsContact O-N 3.12Å; L80-G83 PolarHBondContact O-N 3.25Å; L81-G83 VanDerWaalsContact C-N 3.3Å; G83-I85 PolarHBondContact O-N 3.45Å; G83-P86 WeakPolarHBondContact O-CD 3.35Å; G83-T87 WeakPolarHBondContact O-CB 3.42Å; G83-T87 WeakPolarHBondContact O-CG2 3.4Å; G83-T87 PolarHBondContact O-N 3.31Å; G83-T87 PolarHBondContact O-OG1 3.48Å
84	W	91.3	Very high	88.7	Confident	159 Å²	159	48.1 Å²	48.1	60%	0.602	27%	0.271	S	S	*	.	H	α-helix	trans	-65.9	-21.6	-177.5	71.4	-87.9	0	0	0	113.9	T87 R88 L89	W84-T87 WeakPolarHBondContact CA-OG1 3.43Å; W84-R88 WeakPolarHBondContact O-CA 3.48Å; W84-R88 WeakPolarHBondContact O-CB 3.46Å; W84-R88 PolarHBondContact O-N 3.36Å; W84-L89 HydrophobicContact CE3-CB 4.28Å; W84-L89 HydrophobicContact CH2-CD2 4.39Å; W84-L89 HydrophobicContact CZ3-CB 4.02Å; W84-L89 HydrophobicContact CZ3-CD2 4.09Å; W84-L89 PolarHBondContact O-N 3.02Å
85	I	91.1	Very high	89.4	Confident	33 Å²	33	47.5 Å²	47.5	17%	0.169	27%	0.272	C	S	.	.	I	π-helix	trans	-66.4	-60.4	179.2	-68.2	170.1	0	0	0	110.1	G83 T87 L89 V90 P334	G83-I85 PolarHBondContact O-N 3.45Å; I85-T87 PolarHBondContact O-N 3.48Å; I85-L89 WeakPolarHBondContact O-CB 3.48Å; I85-L89 PolarHBondContact O-N 2.92Å; I85-V90 HydrophobicContact CG2-CG2 4.48Å; I85-V90 WeakPolarHBondContact O-CG2 3.48Å; I85-V90 PolarHBondContact O-N 3.41Å; I85-P334 HydrophobicContact CG2-CB 4.05Å; I85-P334 HydrophobicContact CG2-CG 3.8Å
86	P	90	Very high	90.2	Very high	2 Å²	2	47.8 Å²	47.8	1%	0.013	26%	0.262	C	S	.	.	I	π-helix	trans	-70.9	-25.5	177.7	-21.9	37.1	0	0	0	114.4	L81 G83 P91 H146 Q150 Y329	L81-P86 WeakPolarHBondContact O-CB 3.41Å; L81-P86 WeakPolarHBondContact O-CG 3.42Å; G83-P86 WeakPolarHBondContact O-CD 3.35Å; P86-P91 VanDerWaalsContact O-CD 3.29Å; P86-P91 WeakPolarHBondContact O-CD 3.43Å; P86-H146 WeakPolarHBondContact O-CB 3.46Å; P86-H146 PolarHBondContact O-ND1 3.33Å; P86-Q150 VanDerWaalsContact C-NE2 3.26Å; P86-Q150 PolarHBondContact O-NE2 2.95Å; P86-Q150 VanDerWaalsContact O-NE2 3.09Å; P86-Y329 HydrophobicContact CG-CE1 4.26Å
87	T	91.6	Very high	91	Very high	33 Å²	33	44.6 Å²	44.6	20%	0.202	24%	0.239	C	C	.	.	I	π-helix	trans	-93.5	-17.6	-174.6	59.8	0	0	0	0	114.9	G83 W84 I85 P91	G83-T87 WeakPolarHBondContact O-CB 3.42Å; G83-T87 WeakPolarHBondContact O-CG2 3.4Å; G83-T87 PolarHBondContact O-N 3.31Å; G83-T87 PolarHBondContact O-OG1 3.48Å; W84-T87 WeakPolarHBondContact CA-OG1 3.43Å; I85-T87 PolarHBondContact O-N 3.48Å; T87-P91 WeakPolarHBondContact O-CG 3.3Å
88	R	93.8	Very high	91.8	Very high	187 Å²	187	46.3 Å²	46.3	71%	0.706	25%	0.249	S	C	*	.	I	π-helix	trans	-130.9	-50.8	-179.3	-56.2	-175.7	-177	178.9	0.4	113.4	W84 A92	W84-R88 WeakPolarHBondContact O-CA 3.48Å; W84-R88 WeakPolarHBondContact O-CB 3.46Å; W84-R88 PolarHBondContact O-N 3.36Å; R88-A92 VanDerWaalsContact O-CB 3.26Å; R88-A92 WeakPolarHBondContact O-CB 3.25Å; R88-A92 PolarHBondContact O-N 3.49Å; R88-A92 VanDerWaalsContact O-N 3.13Å
89	L	94.4	Very high	92.4	Very high	60 Å²	60	46.8 Å²	46.8	31%	0.314	26%	0.263	S	S	.	.	I	π-helix	trans	-68	-53	-176.1	178.5	60.1	0	0	0	111.5	W84 I85 A92 L93 P334	W84-L89 HydrophobicContact CE3-CB 4.28Å; W84-L89 HydrophobicContact CH2-CD2 4.39Å; W84-L89 HydrophobicContact CZ3-CB 4.02Å; W84-L89 HydrophobicContact CZ3-CD2 4.09Å; W84-L89 PolarHBondContact O-N 3.02Å; I85-L89 WeakPolarHBondContact O-CB 3.48Å; I85-L89 PolarHBondContact O-N 2.92Å; L89-A92 PolarHBondContact O-N 2.91Å; L89-L93 HydrophobicContact CD1-CD1 4.28Å; L89-L93 HydrophobicContact CD1-CG 4.3Å; L89-L93 HydrophobicContact CG-CD1 4.21Å; L89-L93 WeakPolarHBondContact O-CG 3.38Å; L89-L93 PolarHBondContact O-N 2.87Å; L89-P334 HydrophobicContact CD2-CB 4.18Å
90	V	94.5	Very high	92.8	Very high	0 Å²	0	46.4 Å²	46.4	0%	0	25%	0.254	C	S	.	.	H	α-helix	trans	-57.4	-51	179.3	174.1	0	0	0	0	112.8	I85 A92 L93 Y94 H146 V333 A337	I85-V90 HydrophobicContact CG2-CG2 4.48Å; I85-V90 WeakPolarHBondContact O-CG2 3.48Å; I85-V90 PolarHBondContact O-N 3.41Å; V90-A92 VanDerWaalsContact C-N 3.31Å; V90-A92 PolarHBondContact O-N 3.4Å; V90-L93 PolarHBondContact O-N 3.47Å; V90-Y94 HydrophobicContact CG1-CD2 3.91Å; V90-Y94 HydrophobicContact CG1-CE2 3.42Å; V90-Y94 VanDerWaalsContact CG1-CE2 3.42Å; V90-Y94 PolarHBondContact O-N 3.26Å; V90-H146 WeakPolarHBondContact CG1-NE2 3.3Å; V90-V333 HydrophobicContact CG2-CG1 3.73Å; V90-A337 HydrophobicContact CB-CB 4.47Å; V90-A337 HydrophobicContact CG1-CB 4.11Å; V90-A337 HydrophobicContact CG2-CB 4.23Å
91	P	95.7	Very high	93.1	Very high	6 Å²	6	44.6 Å²	44.6	4%	0.039	24%	0.244	C	C	.	.	H	α-helix	trans	-64.4	-31.5	176.5	21	-31.1	0	0	0	113.3	P86 T87 G95 L143 H146 L147	P86-P91 VanDerWaalsContact O-CD 3.29Å; P86-P91 WeakPolarHBondContact O-CD 3.43Å; T87-P91 WeakPolarHBondContact O-CG 3.3Å; P91-G95 PolarHBondContact O-N 3.04Å; P91-L143 HydrophobicContact CB-CD1 3.44Å; P91-L143 VanDerWaalsContact CB-CD1 3.44Å; P91-L143 WeakPolarHBondContact O-CD1 3.35Å; P91-H146 HydrophobicContact CB-CB 4.03Å; P91-H146 HydrophobicContact CG-CB 3.97Å; P91-L147 HydrophobicContact CB-CD2 4.02Å; P91-L147 HydrophobicContact CB-CG 4.19Å; P91-L147 HydrophobicContact CG-CD2 4.31Å
92	A	96.4	Very high	93.6	Very high	63 Å²	63	47.9 Å²	47.9	52%	0.521	26%	0.262	S	S	.	.	H	α-helix	trans	-65.7	-39.8	172.9	0	0	0	0	0	112.3	R88 L89 V90 G95 L96	R88-A92 VanDerWaalsContact O-CB 3.26Å; R88-A92 WeakPolarHBondContact O-CB 3.25Å; R88-A92 PolarHBondContact O-N 3.49Å; R88-A92 VanDerWaalsContact O-N 3.13Å; L89-A92 PolarHBondContact O-N 2.91Å; V90-A92 VanDerWaalsContact C-N 3.31Å; V90-A92 PolarHBondContact O-N 3.4Å; A92-G95 PolarHBondContact O-N 3.48Å; A92-L96 WeakPolarHBondContact O-CB 3.5Å; A92-L96 PolarHBondContact O-N 3.37Å
93	L	95.6	Very high	93.8	Very high	22 Å²	22	48.3 Å²	48.3	12%	0.115	27%	0.269	C	S	.	.	H	α-helix	trans	-65.1	-46.4	175.3	-66.4	173.9	0	0	0	111.7	L89 V90 G95 L96 V97 A337 L338 L341	L89-L93 HydrophobicContact CD1-CD1 4.28Å; L89-L93 HydrophobicContact CD1-CG 4.3Å; L89-L93 HydrophobicContact CG-CD1 4.21Å; L89-L93 WeakPolarHBondContact O-CG 3.38Å; L89-L93 PolarHBondContact O-N 2.87Å; V90-L93 PolarHBondContact O-N 3.47Å; L93-G95 PolarHBondContact O-N 2.89Å; L93-L96 WeakPolarHBondContact O-CB 3.25Å; L93-L96 PolarHBondContact O-N 2.73Å; L93-V97 PolarHBondContact O-N 3.18Å; L93-A337 HydrophobicContact CB-CB 4.24Å; L93-A337 HydrophobicContact CD1-CB 3.74Å; L93-L338 HydrophobicContact CD1-CD2 4Å; L93-L338 HydrophobicContact CD1-CG 4.08Å; L93-L338 HydrophobicContact CD2-CD2 4.07Å; L93-L341 HydrophobicContact CD2-CD1 4.19Å
94	Y	96.3	Very high	93.9	Very high	4 Å²	4	48.5 Å²	48.5	2%	0.016	27%	0.268	C	S	.	.	H	α-helix	trans	-64.7	-38.8	175.1	-65.5	-27	0	0	0	112.5	V90 L96 V97 V98 L139 R142 H146 A337 T340	V90-Y94 HydrophobicContact CG1-CD2 3.91Å; V90-Y94 HydrophobicContact CG1-CE2 3.42Å; V90-Y94 VanDerWaalsContact CG1-CE2 3.42Å; V90-Y94 PolarHBondContact O-N 3.26Å; Y94-L96 VanDerWaalsContact C-N 3.32Å; Y94-L96 PolarHBondContact O-N 3.1Å; Y94-V97 PolarHBondContact O-N 2.94Å; Y94-V98 WeakPolarHBondContact O-CG2 3.32Å; Y94-V98 PolarHBondContact O-N 3.1Å; Y94-L139 HydrophobicContact CD1-CD1 4.24Å; Y94-L139 HydrophobicContact CD1-CD2 3.5Å; Y94-L139 HydrophobicContact CD1-CG 4.48Å; Y94-L139 HydrophobicContact CD2-CD2 4.27Å; Y94-L139 HydrophobicContact CE1-CD2 3.82Å; Y94-L139 HydrophobicContact CG-CD2 3.76Å; Y94-R142 HydrophobicContact CD2-CB 4.4Å; Y94-R142 HydrophobicContact CE2-CB 4.27Å; Y94-H146 AromaticContact CD2-CD2 3.97Å; Y94-H146 AromaticContact CE2-CD2 3.71Å; Y94-H146 AromaticContact CE2-NE2 3.57Å; Y94-A337 HydrophobicContact CE1-CB 3.91Å; Y94-T340 HydrophobicContact CD1-CG2 4.49Å; Y94-T340 HydrophobicContact CE1-CG2 3.93Å
95	G	96.5	Very high	94	Very high	24 Å²	24	41 Å²	41	25%	0.247	24%	0.24	C	C	.	.	H	α-helix	trans	-59.9	-40.6	173.2	0	0	0	0	0	112.4	P91 A92 L93 V98 A99	P91-G95 PolarHBondContact O-N 3.04Å; A92-G95 PolarHBondContact O-N 3.48Å; L93-G95 PolarHBondContact O-N 2.89Å; G95-V98 PolarHBondContact O-N 3.34Å; G95-A99 VanDerWaalsContact O-CB 3.23Å; G95-A99 WeakPolarHBondContact O-CB 3.29Å; G95-A99 PolarHBondContact O-N 3.24Å
96	L	95.4	Very high	94.2	Very high	86 Å²	86	40.8 Å²	40.8	45%	0.45	25%	0.246	S	C	.	.	H	α-helix	trans	-63	-43.2	174	-178.5	64.5	0	0	0	111.9	A92 L93 Y94 A99 V100 L341	A92-L96 WeakPolarHBondContact O-CB 3.5Å; A92-L96 PolarHBondContact O-N 3.37Å; L93-L96 WeakPolarHBondContact O-CB 3.25Å; L93-L96 PolarHBondContact O-N 2.73Å; Y94-L96 VanDerWaalsContact C-N 3.32Å; Y94-L96 PolarHBondContact O-N 3.1Å; L96-A99 PolarHBondContact O-N 3.12Å; L96-V100 HydrophobicContact CD1-CG2 3.71Å; L96-V100 WeakPolarHBondContact O-CB 3.4Å; L96-V100 PolarHBondContact O-N 3.08Å; L96-L341 HydrophobicContact CD2-CD2 3.91Å; L96-L341 HydrophobicContact CG-CD2 4.38Å
97	V	95.3	Very high	94.3	Very high	0 Å²	0	42.6 Å²	42.6	0%	0	26%	0.255	C	S	.	.	I	π-helix	trans	-63	-42.3	176.2	175.7	0	0	0	0	111.8	L93 Y94 G101 L135 L139 L341 S343	L93-V97 PolarHBondContact O-N 3.18Å; Y94-V97 PolarHBondContact O-N 2.94Å; V97-G101 WeakPolarHBondContact O-CA 3.5Å; V97-G101 PolarHBondContact O-N 3.01Å; V97-L135 HydrophobicContact CG1-CD2 4.03Å; V97-L139 HydrophobicContact CB-CD1 3.63Å; V97-L139 HydrophobicContact CG1-CD1 3.48Å; V97-L139 VanDerWaalsContact CG1-CD1 3.48Å; V97-L139 HydrophobicContact CG2-CD1 4.49Å; V97-L341 HydrophobicContact CG2-CD2 3.72Å; V97-L341 HydrophobicContact CG2-CG 4.43Å; V97-S343 WeakPolarHBondContact CG1-OG 3.33Å
98	V	96.4	Very high	94.3	Very high	37 Å²	37	41 Å²	41	22%	0.224	25%	0.246	C	C	.	.	I	π-helix	trans	-65.7	-45.2	175.3	175.5	0	0	0	0	110.9	Y94 G95 L102 L139 P140	Y94-V98 WeakPolarHBondContact O-CG2 3.32Å; Y94-V98 PolarHBondContact O-N 3.1Å; G95-V98 PolarHBondContact O-N 3.34Å; V98-L102 WeakPolarHBondContact O-CB 3.08Å; V98-L102 PolarHBondContact O-N 2.84Å; V98-L139 HydrophobicContact CG2-CB 3.73Å; V98-L139 HydrophobicContact CG2-CD1 4.18Å; V98-P140 HydrophobicContact CG2-CG 4.46Å
99	A	95	Very high	94.3	Very high	67 Å²	67	34 Å²	34	55%	0.554	22%	0.222	S	C	*	.	I	π-helix	trans	-69	-34.3	-176.4	0	0	0	0	0	114.1	G95 L96 P103	G95-A99 VanDerWaalsContact O-CB 3.23Å; G95-A99 WeakPolarHBondContact O-CB 3.29Å; G95-A99 PolarHBondContact O-N 3.24Å; L96-A99 PolarHBondContact O-N 3.12Å; A99-P103 WeakPolarHBondContact O-CD 3.38Å; A99-P103 WeakPolarHBondContact O-CG 3.49Å
100	V	92.8	Very high	94.2	Very high	64 Å²	64	36.7 Å²	36.7	39%	0.388	23%	0.228	S	C	.	.	I	π-helix	trans	-102.9	-47.2	-177.5	178.1	0	0	0	0	111.8	L96 P103 A104 C344	L96-V100 HydrophobicContact CD1-CG2 3.71Å; L96-V100 WeakPolarHBondContact O-CB 3.4Å; L96-V100 PolarHBondContact O-N 3.08Å; V100-P103 WeakPolarHBondContact O-CD 3.44Å; V100-P103 WeakPolarHBondContact O-CG 3.36Å; V100-A104 WeakPolarHBondContact O-CB 3.35Å; V100-A104 PolarHBondContact O-N 3.32Å; V100-A104 VanDerWaalsContact O-N 3.12Å; V100-C344 HydrophobicContact CG1-CB 4.4Å
101	G	92.1	Very high	93.9	Very high	1 Å²	1	36.7 Å²	36.7	1%	0.01	23%	0.228	C	C	.	.	I	π-helix	trans	-65.7	-41.5	-176	0	0	0	0	0	113.2	V97 N105	V97-G101 WeakPolarHBondContact O-CA 3.5Å; V97-G101 PolarHBondContact O-N 3.01Å; G101-N105 VanDerWaalsContact O-CB 3.27Å; G101-N105 WeakPolarHBondContact O-CB 3.45Å; G101-N105 PolarHBondContact O-N 3.25Å; G101-N105 PolarHBondContact O-ND2 2.94Å
102	L	93.4	Very high	93.6	Very high	70 Å²	70	36.5 Å²	36.5	37%	0.366	23%	0.227	S	C	.	.	H	α-helix	trans	-61.4	-55.4	179.5	-169.8	76.9	0	0	0	112.7	V98 G106 L133 A136	V98-L102 WeakPolarHBondContact O-CB 3.08Å; V98-L102 PolarHBondContact O-N 2.84Å; L102-G106 PolarHBondContact O-N 2.81Å; L102-L133 HydrophobicContact CD1-CD2 3.83Å; L102-A136 HydrophobicContact CB-CB 4.07Å; L102-A136 HydrophobicContact CD1-CB 3.71Å
103	P	92.9	Very high	93.3	Very high	78 Å²	78	35 Å²	35	51%	0.506	21%	0.214	S	C	.	.	H	α-helix	trans	-68.3	-36.6	178.9	26.3	-34.5	0	0	0	112.9	A99 V100 L107	A99-P103 WeakPolarHBondContact O-CD 3.38Å; A99-P103 WeakPolarHBondContact O-CG 3.49Å; V100-P103 WeakPolarHBondContact O-CD 3.44Å; V100-P103 WeakPolarHBondContact O-CG 3.36Å; P103-L107 VanDerWaalsContact O-CB 3.28Å; P103-L107 WeakPolarHBondContact O-CB 3.49Å; P103-L107 PolarHBondContact O-N 3.48Å
104	A	91.3	Very high	92.9	Very high	23 Å²	23	37.8 Å²	37.8	19%	0.19	23%	0.232	C	C	.	.	H	α-helix	trans	-69.6	-47.2	-177.6	0	0	0	0	0	112.3	V100 A108 P347	V100-A104 WeakPolarHBondContact O-CB 3.35Å; V100-A104 PolarHBondContact O-N 3.32Å; V100-A104 VanDerWaalsContact O-N 3.12Å; A104-A108 WeakPolarHBondContact O-CB 3.25Å; A104-A108 PolarHBondContact O-N 2.94Å; A104-P347 HydrophobicContact CB-CB 3.95Å; A104-P347 HydrophobicContact CB-CG 3.54Å
105	N	94.7	Very high	92.3	Very high	0 Å²	0	43.7 Å²	43.7	0%	0	26%	0.255	C	S	.	.	H	α-helix	trans	-72.8	-31.2	176.8	-67.8	-63.7	0	0	0	112.1	G101 A108 L109 A129 D132 L133 S343 Y350	G101-N105 VanDerWaalsContact O-CB 3.27Å; G101-N105 WeakPolarHBondContact O-CB 3.45Å; G101-N105 PolarHBondContact O-N 3.25Å; G101-N105 PolarHBondContact O-ND2 2.94Å; N105-A108 PolarHBondContact O-N 3.47Å; N105-L109 VanDerWaalsContact O-CB 3.32Å; N105-L109 WeakPolarHBondContact O-CB 3.43Å; N105-L109 PolarHBondContact O-N 3.41Å; N105-A129 HydrophobicContact CB-CB 4.44Å; N105-D132 HydrophobicContact CB-CB 4.17Å; N105-L133 HydrophobicContact CB-CD2 4.19Å; N105-L133 HydrophobicContact CB-CG 4.05Å; N105-S343 PolarHBondContact ND2-O 3.37Å; N105-Y350 WeakPolarHBondContact OD1-CE2 3.26Å
106	G	94.6	Very high	91.6	Very high	29 Å²	29	43.7 Å²	43.7	30%	0.299	25%	0.249	S	C	.	.	H	α-helix	trans	-62.5	-47.6	171.6	0	0	0	0	0	112.5	L102 A108 W110	L102-G106 PolarHBondContact O-N 2.81Å; G106-A108 VanDerWaalsContact C-N 3.35Å; G106-W110 WeakPolarHBondContact O-CB 3.39Å; G106-W110 PolarHBondContact O-N 2.73Å
107	L	91.3	Very high	91	Very high	41 Å²	41	43.6 Å²	43.6	22%	0.215	25%	0.254	C	S	.	.	H	α-helix	trans	-61.6	-43.5	173.7	-179.9	66.3	0	0	0	111.2	P103 W110 V111 F357 V361 I364	P103-L107 VanDerWaalsContact O-CB 3.28Å; P103-L107 WeakPolarHBondContact O-CB 3.49Å; P103-L107 PolarHBondContact O-N 3.48Å; L107-W110 HydrophobicContact CD1-CE3 3.99Å; L107-W110 HydrophobicContact CD1-CZ3 4.28Å; L107-W110 PolarHBondContact O-N 3.4Å; L107-V111 HydrophobicContact CD1-CG2 4.35Å; L107-V111 WeakPolarHBondContact O-CG2 3.32Å; L107-V111 PolarHBondContact O-N 3.35Å; L107-F357 HydrophobicContact CB-CE2 4.41Å; L107-F357 HydrophobicContact CD2-CE2 4.1Å; L107-F357 HydrophobicContact CG-CE2 3.96Å; L107-V361 HydrophobicContact CD2-CG2 4.07Å; L107-I364 HydrophobicContact CD1-CD1 4.29Å; L107-I364 HydrophobicContact CD2-CD1 3.81Å
108	A	91.1	Very high	90.5	Very high	0 Å²	0	52.3 Å²	52.3	0%	0	29%	0.287	C	S	.	.	H	α-helix	trans	-62.7	-49.6	179.8	0	0	0	0	0	111.9	A104 N105 G106 W110 V111 L112 Y350 F357	A104-A108 WeakPolarHBondContact O-CB 3.25Å; A104-A108 PolarHBondContact O-N 2.94Å; N105-A108 PolarHBondContact O-N 3.47Å; G106-A108 VanDerWaalsContact C-N 3.35Å; A108-W110 VanDerWaalsContact C-N 3.3Å; A108-W110 PolarHBondContact O-N 2.93Å; A108-V111 PolarHBondContact O-N 2.97Å; A108-L112 WeakPolarHBondContact O-CB 3.18Å; A108-L112 WeakPolarHBondContact O-CG 3.29Å; A108-L112 PolarHBondContact O-N 3.24Å; A108-Y350 HydrophobicContact CB-CD2 3.22Å; A108-Y350 HydrophobicContact CB-CE2 3.7Å; A108-Y350 HydrophobicContact CB-CG 3.98Å; A108-F357 VanDerWaalsContact CA-CE2 3.47Å; A108-F357 HydrophobicContact CB-CD2 4.28Å; A108-F357 HydrophobicContact CB-CE2 3.69Å; A108-F357 HydrophobicContact CB-CZ 4.27Å
109	L	94.3	Very high	90	Very high	39 Å²	39	55 Å²	55	20%	0.204	30%	0.3	C	S	.	.	H	α-helix	trans	-59.2	-42.1	177.2	-177.2	59.8	0	0	0	111.2	N105 A113 M126 A129 V130 L133	N105-L109 VanDerWaalsContact O-CB 3.32Å; N105-L109 WeakPolarHBondContact O-CB 3.43Å; N105-L109 PolarHBondContact O-N 3.41Å; L109-A113 WeakPolarHBondContact O-CB 3.45Å; L109-A113 PolarHBondContact O-N 2.97Å; L109-M126 HydrophobicContact CD1-CB 3.99Å; L109-M126 HydrophobicContact CD1-CE 3.92Å; L109-M126 HydrophobicContact CD1-CG 4.12Å; L109-A129 HydrophobicContact CB-CB 4.16Å; L109-V130 HydrophobicContact CD1-CG2 3.98Å; L109-V130 HydrophobicContact CD2-CG2 3.69Å; L109-L133 HydrophobicContact CB-CD1 4.34Å; L109-L133 HydrophobicContact CD2-CD1 3.64Å
110	W	92.8	Very high	89.5	Confident	116 Å²	116	52.8 Å²	52.8	44%	0.439	28%	0.279	S	S	.	.	H	α-helix	trans	-62.5	-46.3	176	175.5	74.1	0	0	0	112.9	G106 L107 A108 A113 T114 K360	G106-W110 WeakPolarHBondContact O-CB 3.39Å; G106-W110 PolarHBondContact O-N 2.73Å; L107-W110 HydrophobicContact CD1-CE3 3.99Å; L107-W110 HydrophobicContact CD1-CZ3 4.28Å; L107-W110 PolarHBondContact O-N 3.4Å; A108-W110 VanDerWaalsContact C-N 3.3Å; A108-W110 PolarHBondContact O-N 2.93Å; W110-A113 PolarHBondContact O-N 3.4Å; W110-T114 WeakPolarHBondContact O-CB 3.23Å; W110-T114 WeakPolarHBondContact O-CG2 3.38Å; W110-T114 PolarHBondContact O-N 2.91Å; W110-T114 VanDerWaalsContact O-N 3.11Å; W110-T114 PolarHBondContact O-OG1 2.88Å; W110-K360 HydrophobicContact CZ3-CD 4.3Å; W110-K360 HydrophobicContact CZ3-CG 4.44Å
111	V	88.9	Confident	89.2	Confident	0 Å²	0	50.7 Å²	50.7	0%	0	27%	0.267	C	S	.	.	H	α-helix	trans	-64.7	-47.8	177.6	174.2	0	0	0	0	110.9	L107 A108 A113 T114 R115 V116 E356 F357 K360	L107-V111 HydrophobicContact CD1-CG2 4.35Å; L107-V111 WeakPolarHBondContact O-CG2 3.32Å; L107-V111 PolarHBondContact O-N 3.35Å; A108-V111 PolarHBondContact O-N 2.97Å; V111-A113 VanDerWaalsContact C-N 3.3Å; V111-A113 PolarHBondContact O-N 3.38Å; V111-T114 PolarHBondContact O-N 3.45Å; V111-R115 HydrophobicContact CG1-CB 4.1Å; V111-R115 HydrophobicContact CG1-CG 4.32Å; V111-R115 WeakPolarHBondContact O-CA 3.42Å; V111-R115 WeakPolarHBondContact O-CB 3.26Å; V111-R115 PolarHBondContact O-N 3.26Å; V111-V116 HydrophobicContact CG1-CG2 4.2Å; V111-V116 PolarHBondContact O-N 2.9Å; V111-E356 HydrophobicContact CG1-CB 4.13Å; V111-F357 HydrophobicContact CB-CD2 4.17Å; V111-F357 HydrophobicContact CG1-CB 4.01Å; V111-F357 HydrophobicContact CG1-CD2 4.47Å; V111-F357 HydrophobicContact CG2-CD2 4.14Å; V111-K360 HydrophobicContact CG2-CB 4.37Å; V111-K360 HydrophobicContact CG2-CG 4.17Å
112	L	89.2	Confident	89	Confident	3 Å²	3	51 Å²	51	2%	0.016	27%	0.269	C	S	.	.	H	α-helix	trans	-63.2	-34.9	179	-66.9	167.9	0	0	0	112.2	A108 V116 T122 L125 M126 Y350	A108-L112 WeakPolarHBondContact O-CB 3.18Å; A108-L112 WeakPolarHBondContact O-CG 3.29Å; A108-L112 PolarHBondContact O-N 3.24Å; L112-V116 HydrophobicContact CD2-CG2 4.24Å; L112-T122 HydrophobicContact CB-CG2 4.2Å; L112-T122 HydrophobicContact CD2-CG2 3.91Å; L112-L125 HydrophobicContact CD1-CB 3.93Å; L112-M126 HydrophobicContact CB-CG 3.55Å; L112-M126 HydrophobicContact CB-SD 4.25Å; L112-M126 HydrophobicContact CD1-CG 4.21Å; L112-M126 HydrophobicContact CG-CG 4.49Å; L112-Y350 HydrophobicContact CD1-CD1 4.13Å; L112-Y350 HydrophobicContact CD1-CE1 4.42Å; L112-Y350 HydrophobicContact CD1-CG 4.45Å
113	A	90.1	Very high	89	Confident	31 Å²	31	48.5 Å²	48.5	26%	0.256	26%	0.257	S	S	.	.	H	α-helix	trans	-74.6	-31	179.1	0	0	0	0	0	114.3	L109 W110 V111 R118 M126	L109-A113 WeakPolarHBondContact O-CB 3.45Å; L109-A113 PolarHBondContact O-N 2.97Å; W110-A113 PolarHBondContact O-N 3.4Å; V111-A113 VanDerWaalsContact C-N 3.3Å; V111-A113 PolarHBondContact O-N 3.38Å; A113-R118 PolarHBondContact O-NH2 2.98Å; A113-M126 HydrophobicContact CB-CE 3.62Å
114	T	87.1	Confident	89	Confident	81 Å²	81	44.9 Å²	44.9	50%	0.497	23%	0.233	S	C	.	.	H	α-helix	trans	-119.3	-26.2	-166.6	65.9	0	0	0	0	115.4	W110 V111	W110-T114 WeakPolarHBondContact O-CB 3.23Å; W110-T114 WeakPolarHBondContact O-CG2 3.38Å; W110-T114 PolarHBondContact O-N 2.91Å; W110-T114 VanDerWaalsContact O-N 3.11Å; W110-T114 PolarHBondContact O-OG1 2.88Å; V111-T114 PolarHBondContact O-N 3.45Å
115	R	83.9	Confident	89	Confident	128 Å²	128	44 Å²	44	48%	0.483	23%	0.226	S	C	.	.	T	Hydrogen-bonded Turn	trans	-113.3	-25.9	-173.1	-52.8	-50.2	-169.2	103.8	-13.9	113.8	V111 E356	V111-R115 HydrophobicContact CG1-CB 4.1Å; V111-R115 HydrophobicContact CG1-CG 4.32Å; V111-R115 WeakPolarHBondContact O-CA 3.42Å; V111-R115 WeakPolarHBondContact O-CB 3.26Å; V111-R115 PolarHBondContact O-N 3.26Å; R115-E356 HydrophobicContact CB-CB 4.21Å; R115-E356 HydrophobicContact CB-CG 4.44Å
116	V	81.1	Confident	89	Confident	23 Å²	23	45.6 Å²	45.6	14%	0.139	23%	0.233	C	C	.	.	S	Bend	trans	-99.7	136.2	-175.5	-174.6	0	0	0	0	109.9	V111 L112 T122 S354	V111-V116 HydrophobicContact CG1-CG2 4.2Å; V111-V116 PolarHBondContact O-N 2.9Å; L112-V116 HydrophobicContact CD2-CG2 4.24Å; V116-T122 HydrophobicContact CB-CG2 4.06Å; V116-T122 HydrophobicContact CG1-CG2 3.79Å; V116-S354 WeakPolarHBondContact CG2-OG 3.19Å
117	P	83	Confident	89.1	Confident	84 Å²	84	45.8 Å²	45.8	55%	0.545	23%	0.228	S	C	.	.			trans	-55.2	142	173.1	-26.7	35.5	0	0	0	112.3	L119 T122	P117-L119 HydrophobicContact CB-CG 4.37Å; P117-L119 PolarHBondContact O-N 2.92Å; P117-T122 PolarHBondContact O-OG1 3.27Å
118	R	83.8	Confident	89.3	Confident	184 Å²	184	43.9 Å²	43.9	69%	0.694	22%	0.217	S	C	*	.			trans	-74.1	77.4	178.3	-69.7	-163	176.7	118.8	10.9	111.7	A113	A113-R118 PolarHBondContact O-NH2 2.98Å
119	L	86.1	Confident	89.5	Confident	94 Å²	94	43.9 Å²	43.9	49%	0.492	22%	0.217	S	C	.	.			trans	-91	156.5	171.5	-62.7	170	0	0	0	110.4	P117 S121 T122 V123	P117-L119 HydrophobicContact CB-CG 4.37Å; P117-L119 PolarHBondContact O-N 2.92Å; L119-S121 VanDerWaalsContact C-N 3.29Å; L119-S121 PolarHBondContact O-N 3.39Å; L119-T122 WeakPolarHBondContact O-CA 3.41Å; L119-T122 WeakPolarHBondContact O-CB 3.31Å; L119-T122 PolarHBondContact O-N 3.39Å; L119-V123 PolarHBondContact O-N 2.96Å; L119-V123 VanDerWaalsContact O-N 3.1Å
120	P	85.5	Confident	89.6	Confident	19 Å²	19	44.6 Å²	44.6	12%	0.123	22%	0.223	C	C	.	.	H	α-helix	trans	-39.2	-53.6	170.2	-35.1	35.6	0	0	0	114.4	T122 V123 L124 R198 T203	P120-T122 PolarHBondContact O-N 2.87Å; P120-V123 PolarHBondContact O-N 3.3Å; P120-L124 PolarHBondContact O-N 2.94Å; P120-R198 HydrophobicContact CG-CB 4.36Å; P120-R198 WeakPolarHBondContact CG-O 3.34Å; P120-T203 WeakPolarHBondContact CA-OG1 3.01Å; P120-T203 HydrophobicContact CB-CG2 4.47Å; P120-T203 VanDerWaalsContact CB-OG1 3.28Å; P120-T203 WeakPolarHBondContact CB-OG1 3.46Å; P120-T203 WeakPolarHBondContact O-CG2 3.44Å
121	S	85.5	Confident	89.8	Confident	20 Å²	20	39.2 Å²	39.2	14%	0.14	20%	0.204	C	C	.	.	H	α-helix	trans	-67.7	-34.7	180	17.5	0	0	0	0	113.3	L119 V123 L124 L125 D183 R184 R198	L119-S121 VanDerWaalsContact C-N 3.29Å; L119-S121 PolarHBondContact O-N 3.39Å; S121-V123 VanDerWaalsContact C-N 3.31Å; S121-V123 PolarHBondContact O-N 2.95Å; S121-L124 PolarHBondContact O-N 3.38Å; S121-L125 VanDerWaalsContact O-CG 3.28Å; S121-L125 WeakPolarHBondContact O-CG 3.22Å; S121-L125 PolarHBondContact O-N 3.07Å; S121-L125 VanDerWaalsContact O-N 3.09Å; S121-D183 WeakPolarHBondContact CB-OD2 3.18Å; S121-R184 VanDerWaalsContact CB-NH2 3.3Å; S121-R184 PolarHBondContact OG-NH2 3.07Å; S121-R198 PolarHBondContact OG-NH2 2.81Å
122	T	88.6	Confident	90.2	Very high	8 Å²	8	39.3 Å²	39.3	5%	0.049	20%	0.204	C	C	.	.	H	α-helix	trans	-60.8	-43.1	175.2	-44.4	0	0	0	0	110.5	L112 V116 P117 L119 P120 L124 L125 M126	L112-T122 HydrophobicContact CB-CG2 4.2Å; L112-T122 HydrophobicContact CD2-CG2 3.91Å; V116-T122 HydrophobicContact CB-CG2 4.06Å; V116-T122 HydrophobicContact CG1-CG2 3.79Å; P117-T122 PolarHBondContact O-OG1 3.27Å; L119-T122 WeakPolarHBondContact O-CA 3.41Å; L119-T122 WeakPolarHBondContact O-CB 3.31Å; L119-T122 PolarHBondContact O-N 3.39Å; P120-T122 PolarHBondContact O-N 2.87Å; T122-L124 PolarHBondContact O-N 3.45Å; T122-L125 PolarHBondContact O-N 3.23Å; T122-M126 HydrophobicContact CG2-SD 4.39Å; T122-M126 VanDerWaalsContact O-CG 3.27Å; T122-M126 WeakPolarHBondContact O-CG 3.3Å; T122-M126 PolarHBondContact O-N 3.04Å
123	V	92.5	Very high	90.5	Very high	18 Å²	18	40.7 Å²	40.7	11%	0.109	21%	0.211	C	C	.	.	H	α-helix	trans	-66.4	-38	-179.6	173.5	0	0	0	0	112	L119 P120 S121 M126 N127 T203	L119-V123 PolarHBondContact O-N 2.96Å; L119-V123 VanDerWaalsContact O-N 3.1Å; P120-V123 PolarHBondContact O-N 3.3Å; S121-V123 VanDerWaalsContact C-N 3.31Å; S121-V123 PolarHBondContact O-N 2.95Å; V123-M126 PolarHBondContact O-N 2.85Å; V123-N127 PolarHBondContact O-N 3.48Å; V123-N127 VanDerWaalsContact O-N 3.07Å; V123-N127 PolarHBondContact O-ND2 3.46Å; V123-T203 HydrophobicContact CB-CG2 3.82Å; V123-T203 HydrophobicContact CG1-CG2 3.85Å
124	L	93.1	Very high	90.8	Very high	1 Å²	1	43.2 Å²	43.2	1%	0.005	22%	0.22	C	C	.	.	H	α-helix	trans	-62.7	-47.1	173	-71.9	164.7	0	0	0	111.6	P120 S121 T122 M126 N127 L128 A179 V180 D183 T203 L206	P120-L124 PolarHBondContact O-N 2.94Å; S121-L124 PolarHBondContact O-N 3.38Å; T122-L124 PolarHBondContact O-N 3.45Å; L124-M126 VanDerWaalsContact C-N 3.31Å; L124-M126 PolarHBondContact O-N 2.8Å; L124-N127 PolarHBondContact O-N 3.1Å; L124-N127 VanDerWaalsContact O-N 3.11Å; L124-L128 PolarHBondContact O-N 2.93Å; L124-A179 HydrophobicContact CD2-CB 3.7Å; L124-V180 HydrophobicContact CB-CG2 3.78Å; L124-V180 HydrophobicContact CD1-CG2 4.39Å; L124-D183 HydrophobicContact CD1-CB 3.84Å; L124-T203 HydrophobicContact CD2-CG2 4.48Å; L124-T203 HydrophobicContact CG-CG2 3.98Å; L124-L206 HydrophobicContact CD2-CB 4.49Å
125	L	92.4	Very high	91.3	Very high	6 Å²	6	39.4 Å²	39.4	3%	0.031	20%	0.197	C	C	.	.	H	α-helix	trans	-64	-35	178	-64.6	171.9	0	0	0	112.3	L112 S121 T122 L128 A129 V180 I349 Y350 V353	L112-L125 HydrophobicContact CD1-CB 3.93Å; S121-L125 VanDerWaalsContact O-CG 3.28Å; S121-L125 WeakPolarHBondContact O-CG 3.22Å; S121-L125 PolarHBondContact O-N 3.07Å; S121-L125 VanDerWaalsContact O-N 3.09Å; T122-L125 PolarHBondContact O-N 3.23Å; L125-L128 PolarHBondContact O-N 3.28Å; L125-A129 PolarHBondContact O-N 3.1Å; L125-V180 HydrophobicContact CD2-CG2 4.41Å; L125-I349 HydrophobicContact CD2-CG2 3.9Å; L125-Y350 HydrophobicContact CB-CD1 3.93Å; L125-Y350 HydrophobicContact CB-CE1 3.73Å; L125-Y350 HydrophobicContact CD1-CD1 4.31Å; L125-Y350 HydrophobicContact CD2-CD1 3.86Å; L125-Y350 HydrophobicContact CD2-CE1 3.69Å; L125-Y350 HydrophobicContact CG-CD1 4.23Å; L125-Y350 HydrophobicContact CG-CE1 4.21Å; L125-V353 HydrophobicContact CD1-CB 4.3Å; L125-V353 HydrophobicContact CD1-CG1 3.84Å
126	M	94.1	Very high	91.8	Very high	32 Å²	32	33.5 Å²	33.5	16%	0.158	18%	0.175	C	C	.	.	H	α-helix	trans	-65.4	-37.6	171.9	-71.6	178.1	72	0	0	112.5	L109 L112 A113 T122 V123 L124 V130	L109-M126 HydrophobicContact CD1-CB 3.99Å; L109-M126 HydrophobicContact CD1-CE 3.92Å; L109-M126 HydrophobicContact CD1-CG 4.12Å; L112-M126 HydrophobicContact CB-CG 3.55Å; L112-M126 HydrophobicContact CB-SD 4.25Å; L112-M126 HydrophobicContact CD1-CG 4.21Å; L112-M126 HydrophobicContact CG-CG 4.49Å; A113-M126 HydrophobicContact CB-CE 3.62Å; T122-M126 HydrophobicContact CG2-SD 4.39Å; T122-M126 VanDerWaalsContact O-CG 3.27Å; T122-M126 WeakPolarHBondContact O-CG 3.3Å; T122-M126 PolarHBondContact O-N 3.04Å; V123-M126 PolarHBondContact O-N 2.85Å; L124-M126 VanDerWaalsContact C-N 3.31Å; L124-M126 PolarHBondContact O-N 2.8Å; M126-V130 VanDerWaalsContact O-CG2 3.28Å; M126-V130 WeakPolarHBondContact O-CG2 3.46Å; M126-V130 PolarHBondContact O-N 3.29Å
127	N	96.4	Very high	92.4	Very high	34 Å²	34	38 Å²	38	18%	0.182	20%	0.198	C	C	.	.	H	α-helix	trans	-69.4	-36.8	176.7	-82.8	-99.2	0	0	0	111.8	V123 L124 V130 S131 L176 C207 W211	V123-N127 PolarHBondContact O-N 3.48Å; V123-N127 VanDerWaalsContact O-N 3.07Å; V123-N127 PolarHBondContact O-ND2 3.46Å; L124-N127 PolarHBondContact O-N 3.1Å; L124-N127 VanDerWaalsContact O-N 3.11Å; N127-V130 PolarHBondContact O-N 3.36Å; N127-S131 PolarHBondContact O-N 3.24Å; N127-L176 HydrophobicContact CB-CD1 4.26Å; N127-L176 HydrophobicContact CB-CD2 3.82Å; N127-C207 VanDerWaalsContact CG-SG 3.58Å; N127-C207 PolarHBondContact ND2-SG 3Å; N127-C207 VanDerWaalsContact ND2-SG 3.41Å; N127-W211 PolarHBondContact OD1-NE1 3.04Å
128	L	95.2	Very high	92.9	Very high	0 Å²	0	35.3 Å²	35.3	0%	0	18%	0.18	C	C	.	.	H	α-helix	trans	-61.1	-54	173.4	-172.8	63.7	0	0	0	110.6	L124 L125 V130 S131 D132 L176 L177 D346 I349 Y350	L124-L128 PolarHBondContact O-N 2.93Å; L125-L128 PolarHBondContact O-N 3.28Å; L128-V130 VanDerWaalsContact C-N 3.26Å; L128-V130 PolarHBondContact O-N 3.27Å; L128-S131 WeakPolarHBondContact O-CA 3.38Å; L128-S131 VanDerWaalsContact O-CB 3.25Å; L128-S131 WeakPolarHBondContact O-CB 3.22Å; L128-S131 PolarHBondContact O-N 2.93Å; L128-D132 PolarHBondContact O-N 3.49Å; L128-D132 VanDerWaalsContact O-OD2 3.14Å; L128-L176 HydrophobicContact CD1-CB 4.19Å; L128-L177 HydrophobicContact CD1-CD2 4.24Å; L128-L177 HydrophobicContact CD1-CG 4.23Å; L128-L177 HydrophobicContact CD2-CD2 3.64Å; L128-L177 HydrophobicContact CD2-CG 4.5Å; L128-D346 HydrophobicContact CD2-CB 4.05Å; L128-D346 HydrophobicContact CG-CB 4.4Å; L128-I349 HydrophobicContact CD2-CD1 4.36Å; L128-Y350 HydrophobicContact CD2-CE1 4.38Å; L128-Y350 WeakPolarHBondContact CG-OH 3.34Å
129	A	95.9	Very high	93.5	Very high	0 Å²	0	26.6 Å²	26.6	0%	0	15%	0.147	C	C	.	.	H	α-helix	trans	-58.4	-33.9	176.7	0	0	0	0	0	113.5	N105 L109 L125 L133 Y350	N105-A129 HydrophobicContact CB-CB 4.44Å; L109-A129 HydrophobicContact CB-CB 4.16Å; L125-A129 PolarHBondContact O-N 3.1Å; A129-L133 WeakPolarHBondContact O-CB 3.41Å; A129-L133 WeakPolarHBondContact O-CG 3.37Å; A129-L133 PolarHBondContact O-N 2.85Å; A129-Y350 HydrophobicContact CB-CE2 4.27Å; A129-Y350 PolarHBondContact N-OH 3.31Å
130	V	96.9	Very high	93.9	Very high	54 Å²	54	24.9 Å²	24.9	33%	0.327	14%	0.141	S	C	.	.	H	α-helix	trans	-66.2	-43.1	171.5	166.8	0	0	0	0	111.4	L109 M126 N127 L128 D132 L133 L134 W211	L109-V130 HydrophobicContact CD1-CG2 3.98Å; L109-V130 HydrophobicContact CD2-CG2 3.69Å; M126-V130 VanDerWaalsContact O-CG2 3.28Å; M126-V130 WeakPolarHBondContact O-CG2 3.46Å; M126-V130 PolarHBondContact O-N 3.29Å; N127-V130 PolarHBondContact O-N 3.36Å; L128-V130 VanDerWaalsContact C-N 3.26Å; L128-V130 PolarHBondContact O-N 3.27Å; V130-D132 VanDerWaalsContact C-N 3.34Å; V130-D132 PolarHBondContact O-N 2.97Å; V130-L133 PolarHBondContact O-N 3Å; V130-L134 WeakPolarHBondContact O-CG 3.28Å; V130-L134 PolarHBondContact O-N 3.02Å; V130-W211 HydrophobicContact CG1-CH2 4.24Å; V130-W211 HydrophobicContact CG1-CZ2 4.04Å
131	S	96.8	Very high	94.4	Very high	4 Å²	4	26 Å²	26	3%	0.028	15%	0.148	C	C	.	.	H	α-helix	trans	-59	-45.3	175.6	-157.8	0	0	0	0	111.5	N127 L128 L133 L134 L135 H169	N127-S131 PolarHBondContact O-N 3.24Å; L128-S131 WeakPolarHBondContact O-CA 3.38Å; L128-S131 VanDerWaalsContact O-CB 3.25Å; L128-S131 WeakPolarHBondContact O-CB 3.22Å; L128-S131 PolarHBondContact O-N 2.93Å; S131-L133 PolarHBondContact O-N 3.47Å; S131-L134 WeakPolarHBondContact O-CB 3.47Å; S131-L134 PolarHBondContact O-N 3.47Å; S131-L134 VanDerWaalsContact O-N 3.15Å; S131-L135 PolarHBondContact O-N 2.96Å; S131-H169 PolarHBondContact O-CD2 2.8Å
132	D	96.3	Very high	94.8	Very high	1 Å²	1	25.4 Å²	25.4	1%	0.005	14%	0.143	C	C	.	.	H	α-helix	trans	-66.3	-36.1	179.4	-63.1	-37.9	0	0	0	113.1	N105 L128 V130 L135 A136 H169 S343	N105-D132 HydrophobicContact CB-CB 4.17Å; L128-D132 PolarHBondContact O-N 3.49Å; L128-D132 VanDerWaalsContact O-OD2 3.14Å; V130-D132 VanDerWaalsContact C-N 3.34Å; V130-D132 PolarHBondContact O-N 2.97Å; D132-L135 PolarHBondContact O-N 3.2Å; D132-A136 PolarHBondContact O-N 3.16Å; D132-H169 IonicContact OD1-CD2 3.54Å; D132-H169 IonicContact OD1-CE1 2.92Å; D132-H169 IonicContact OD1-NE2 3.9Å; D132-H169 PolarHBondContact OD1-NE2 2.87Å; D132-S343 WeakPolarHBondContact OD1-CB 3.39Å
133	L	96.7	Very high	95.1	Very high	32 Å²	32	26.9 Å²	26.9	17%	0.168	15%	0.15	C	C	.	.	H	α-helix	trans	-66.8	-37.3	171.8	-73.5	170.2	0	0	0	112	L102 N105 L109 A129 V130 S131 A136 L137	L102-L133 HydrophobicContact CD1-CD2 3.83Å; N105-L133 HydrophobicContact CB-CD2 4.19Å; N105-L133 HydrophobicContact CB-CG 4.05Å; L109-L133 HydrophobicContact CB-CD1 4.34Å; L109-L133 HydrophobicContact CD2-CD1 3.64Å; A129-L133 WeakPolarHBondContact O-CB 3.41Å; A129-L133 WeakPolarHBondContact O-CG 3.37Å; A129-L133 PolarHBondContact O-N 2.85Å; V130-L133 PolarHBondContact O-N 3Å; S131-L133 PolarHBondContact O-N 3.47Å; L133-A136 PolarHBondContact O-N 3.46Å; L133-L137 WeakPolarHBondContact O-CG 3.2Å; L133-L137 PolarHBondContact O-N 3.48Å; L133-L137 VanDerWaalsContact O-N 3.15Å
134	L	96	Very high	95.3	Very high	85 Å²	85	27.2 Å²	27.2	45%	0.445	16%	0.155	S	C	.	.	H	α-helix	trans	-64.3	-41.3	173.2	-68.5	178.2	0	0	0	111.6	V130 S131 A136 L137 V138 W211	V130-L134 WeakPolarHBondContact O-CG 3.28Å; V130-L134 PolarHBondContact O-N 3.02Å; S131-L134 WeakPolarHBondContact O-CB 3.47Å; S131-L134 PolarHBondContact O-N 3.47Å; S131-L134 VanDerWaalsContact O-N 3.15Å; L134-A136 PolarHBondContact O-N 2.85Å; L134-L137 PolarHBondContact O-N 2.89Å; L134-V138 VanDerWaalsContact O-CG2 3.25Å; L134-V138 WeakPolarHBondContact O-CG2 3.49Å; L134-V138 PolarHBondContact O-N 3.42Å; L134-V138 VanDerWaalsContact O-N 3.08Å; L134-W211 HydrophobicContact CD1-CH2 3.76Å; L134-W211 HydrophobicContact CD1-CZ3 3.95Å
135	L	96.5	Very high	95.4	Very high	1 Å²	1	27.1 Å²	27.1	1%	0.005	16%	0.155	C	C	.	.	H	α-helix	trans	-57.3	-49.2	171.7	174	67.4	0	0	0	111.1	V97 S131 D132 L137 V138 L139 L166 H169 T340	V97-L135 HydrophobicContact CG1-CD2 4.03Å; S131-L135 PolarHBondContact O-N 2.96Å; D132-L135 PolarHBondContact O-N 3.2Å; L135-L137 PolarHBondContact O-N 3.38Å; L135-L137 VanDerWaalsContact O-N 3.12Å; L135-V138 WeakPolarHBondContact O-CA 3.44Å; L135-V138 PolarHBondContact O-N 3.4Å; L135-L139 HydrophobicContact CD1-CD1 4.26Å; L135-L139 HydrophobicContact CD1-CD2 3.95Å; L135-L139 HydrophobicContact CD1-CG 3.89Å; L135-L139 HydrophobicContact CD2-CD1 4.48Å; L135-L139 HydrophobicContact CG-CD1 4.07Å; L135-L139 HydrophobicContact CG-CG 4.11Å; L135-L139 WeakPolarHBondContact O-CG 3.12Å; L135-L139 PolarHBondContact O-N 2.9Å; L135-L166 HydrophobicContact CD1-CD1 3.73Å; L135-H169 HydrophobicContact CB-CB 4.11Å; L135-H169 HydrophobicContact CD1-CB 4.33Å; L135-H169 VanDerWaalsContact CD2-CE1 3.41Å; L135-H169 WeakPolarHBondContact CD2-CE1 3.26Å; L135-T340 HydrophobicContact CD1-CG2 4.37Å; L135-T340 HydrophobicContact CD2-CG2 4.4Å
136	A	95.6	Very high	95.5	Very high	3 Å²	3	27 Å²	27	3%	0.025	15%	0.154	C	C	.	.	H	α-helix	trans	-60.6	-23.2	-179.5	0	0	0	0	0	113.5	L102 D132 L133 L134 P140	L102-A136 HydrophobicContact CB-CB 4.07Å; L102-A136 HydrophobicContact CD1-CB 3.71Å; D132-A136 PolarHBondContact O-N 3.16Å; L133-A136 PolarHBondContact O-N 3.46Å; L134-A136 PolarHBondContact O-N 2.85Å; A136-P140 VanDerWaalsContact O-CD 3.31Å; A136-P140 WeakPolarHBondContact O-CD 3.18Å
137	L	93	Very high	95.5	Very high	119 Å²	119	30.9 Å²	30.9	62%	0.623	18%	0.175	S	C	*	.	H	α-helix	trans	-85.1	-22.8	171.7	-66	172.7	0	0	0	113.9	L133 L134 L135 P140	L133-L137 WeakPolarHBondContact O-CG 3.2Å; L133-L137 PolarHBondContact O-N 3.48Å; L133-L137 VanDerWaalsContact O-N 3.15Å; L134-L137 PolarHBondContact O-N 2.89Å; L135-L137 PolarHBondContact O-N 3.38Å; L135-L137 VanDerWaalsContact O-N 3.12Å; L137-P140 WeakPolarHBondContact O-CD 3.37Å
138	V	94	Very high	95.4	Very high	27 Å²	27	35.1 Å²	35.1	16%	0.164	19%	0.193	C	C	.	.	H	α-helix	trans	-85.5	-26.5	178.3	169.2	0	0	0	0	112.3	L134 L135 P141 A165	L134-V138 VanDerWaalsContact O-CG2 3.25Å; L134-V138 WeakPolarHBondContact O-CG2 3.49Å; L134-V138 PolarHBondContact O-N 3.42Å; L134-V138 VanDerWaalsContact O-N 3.08Å; L135-V138 WeakPolarHBondContact O-CA 3.44Å; L135-V138 PolarHBondContact O-N 3.4Å; V138-P141 WeakPolarHBondContact O-CD 3.34Å; V138-A165 HydrophobicContact CB-CB 4.43Å; V138-A165 HydrophobicContact CG1-CB 4Å; V138-A165 HydrophobicContact CG2-CB 3.55Å
139	L	95.7	Very high	95.2	Very high	0 Å²	0	36.2 Å²	36.2	0%	0	20%	0.204	C	C	.	.	H	α-helix	trans	-68.5	-34.3	-178.9	-71.1	-178.2	0	0	0	116	Y94 V97 V98 L135 R142 L143 L166	Y94-L139 HydrophobicContact CD1-CD1 4.24Å; Y94-L139 HydrophobicContact CD1-CD2 3.5Å; Y94-L139 HydrophobicContact CD1-CG 4.48Å; Y94-L139 HydrophobicContact CD2-CD2 4.27Å; Y94-L139 HydrophobicContact CE1-CD2 3.82Å; Y94-L139 HydrophobicContact CG-CD2 3.76Å; V97-L139 HydrophobicContact CB-CD1 3.63Å; V97-L139 HydrophobicContact CG1-CD1 3.48Å; V97-L139 VanDerWaalsContact CG1-CD1 3.48Å; V97-L139 HydrophobicContact CG2-CD1 4.49Å; V98-L139 HydrophobicContact CG2-CB 3.73Å; V98-L139 HydrophobicContact CG2-CD1 4.18Å; L135-L139 HydrophobicContact CD1-CD1 4.26Å; L135-L139 HydrophobicContact CD1-CD2 3.95Å; L135-L139 HydrophobicContact CD1-CG 3.89Å; L135-L139 HydrophobicContact CD2-CD1 4.48Å; L135-L139 HydrophobicContact CG-CD1 4.07Å; L135-L139 HydrophobicContact CG-CG 4.11Å; L135-L139 WeakPolarHBondContact O-CG 3.12Å; L135-L139 PolarHBondContact O-N 2.9Å; L139-R142 CarbonylContact O-C 3.58Å; L139-R142 WeakPolarHBondContact O-CA 3.3Å; L139-R142 WeakPolarHBondContact O-CB 3.46Å; L139-R142 PolarHBondContact O-N 3.02Å; L139-R142 VanDerWaalsContact O-N 3.1Å; L139-L143 WeakPolarHBondContact O-CB 3.07Å; L139-L143 PolarHBondContact O-N 3.36Å; L139-L166 HydrophobicContact CD2-CD1 4.32Å
140	P	95.7	Very high	95	Very high	58 Å²	58	36.2 Å²	36.2	38%	0.377	20%	0.204	S	C	.	.	H	α-helix	trans	-61	-40.6	-176.2	-23.7	33.6	0	0	0	115.3	V98 A136 L137 R142 L143 A144	V98-P140 HydrophobicContact CG2-CG 4.46Å; A136-P140 VanDerWaalsContact O-CD 3.31Å; A136-P140 WeakPolarHBondContact O-CD 3.18Å; L137-P140 WeakPolarHBondContact O-CD 3.37Å; P140-R142 PolarHBondContact O-N 3.23Å; P140-L143 WeakPolarHBondContact O-CB 3.21Å; P140-L143 PolarHBondContact O-N 3.47Å; P140-A144 PolarHBondContact O-N 2.88Å
141	P	95.5	Very high	94.9	Very high	42 Å²	42	36.8 Å²	36.8	27%	0.273	20%	0.204	S	C	.	.	H	α-helix	trans	-60.7	-40.3	169.8	-26.5	35.9	0	0	0	113.7	V138 A144 Y145 W152 F154	V138-P141 WeakPolarHBondContact O-CD 3.34Å; P141-A144 PolarHBondContact O-N 3.34Å; P141-Y145 PolarHBondContact O-N 2.7Å; P141-W152 HydrophobicContact CB-CH2 3.78Å; P141-W152 HydrophobicContact CB-CZ3 4.27Å; P141-F154 HydrophobicContact CB-CD2 4.11Å; P141-F154 HydrophobicContact CB-CE2 3.89Å; P141-F154 HydrophobicContact CB-CZ 4.4Å
142	R	94.8	Very high	94.9	Very high	8 Å²	8	36.7 Å²	36.7	3%	0.03	20%	0.203	C	C	.	.	H	α-helix	trans	-66.6	-35.5	174.7	-79.5	-72.7	-171.6	167.6	-3.8	112.3	Y94 L139 P140 Y145 H146 T163 C238	Y94-R142 HydrophobicContact CD2-CB 4.4Å; Y94-R142 HydrophobicContact CE2-CB 4.27Å; L139-R142 CarbonylContact O-C 3.58Å; L139-R142 WeakPolarHBondContact O-CA 3.3Å; L139-R142 WeakPolarHBondContact O-CB 3.46Å; L139-R142 PolarHBondContact O-N 3.02Å; L139-R142 VanDerWaalsContact O-N 3.1Å; P140-R142 PolarHBondContact O-N 3.23Å; R142-Y145 WeakPolarHBondContact O-CB 3.38Å; R142-Y145 PolarHBondContact O-N 3.45Å; R142-H146 PolarHBondContact O-CD2 3.25Å; R142-H146 PolarHBondContact O-N 3.01Å; R142-T163 PolarHBondContact NH2-OG1 2.91Å; R142-C238 PolarHBondContact NH1-O 3.37Å
143	L	95	Very high	94.9	Very high	39 Å²	39	40 Å²	40	20%	0.204	22%	0.224	C	C	.	.	H	α-helix	trans	-64.5	-48.3	174.2	-178.2	61.7	0	0	0	110.8	P91 L139 P140 Y145 H146 L147	P91-L143 HydrophobicContact CB-CD1 3.44Å; P91-L143 VanDerWaalsContact CB-CD1 3.44Å; P91-L143 WeakPolarHBondContact O-CD1 3.35Å; L139-L143 WeakPolarHBondContact O-CB 3.07Å; L139-L143 PolarHBondContact O-N 3.36Å; P140-L143 WeakPolarHBondContact O-CB 3.21Å; P140-L143 PolarHBondContact O-N 3.47Å; L143-Y145 VanDerWaalsContact C-N 3.32Å; L143-Y145 PolarHBondContact O-N 2.9Å; L143-H146 PolarHBondContact O-N 2.98Å; L143-L147 HydrophobicContact CD1-CD1 3.97Å; L143-L147 HydrophobicContact CD1-CG 4.22Å; L143-L147 HydrophobicContact CG-CD1 3.86Å; L143-L147 HydrophobicContact CG-CG 4.46Å; L143-L147 WeakPolarHBondContact O-CB 3.44Å; L143-L147 VanDerWaalsContact O-CG 3.27Å; L143-L147 WeakPolarHBondContact O-CG 3.3Å; L143-L147 PolarHBondContact O-N 2.96Å
144	A	95.9	Very high	94.8	Very high	25 Å²	25	43.2 Å²	43.2	21%	0.207	24%	0.237	C	C	.	.	H	α-helix	trans	-59.3	-41.4	176.5	0	0	0	0	0	112.4	P140 P141 L147 H148 F154	P140-A144 PolarHBondContact O-N 2.88Å; P141-A144 PolarHBondContact O-N 3.34Å; A144-L147 PolarHBondContact O-N 2.89Å; A144-H148 WeakPolarHBondContact O-CB 3.46Å; A144-H148 PolarHBondContact O-N 2.99Å; A144-H148 PolarHBondContact O-ND1 2.84Å; A144-F154 HydrophobicContact CB-CE2 4.18Å; A144-F154 HydrophobicContact CB-CZ 4.04Å
145	Y	95.7	Very high	94.9	Very high	0 Å²	0	40.6 Å²	40.6	0%	0	23%	0.23	C	C	.	.	H	α-helix	trans	-56.3	-51.4	174.9	167.8	-107.8	0	0	0	113.2	P141 R142 L143 H148 Q150 H151 W152 C238 D240	P141-Y145 PolarHBondContact O-N 2.7Å; R142-Y145 WeakPolarHBondContact O-CB 3.38Å; R142-Y145 PolarHBondContact O-N 3.45Å; L143-Y145 VanDerWaalsContact C-N 3.32Å; L143-Y145 PolarHBondContact O-N 2.9Å; Y145-H148 PolarHBondContact O-N 3.15Å; Y145-Q150 HydrophobicContact CE2-CB 4.24Å; Y145-Q150 WeakPolarHBondContact CE2-O 3.28Å; Y145-Q150 WeakPolarHBondContact O-CA 3.45Å; Y145-Q150 PolarHBondContact O-N 3.1Å; Y145-H151 VanDerWaalsContact CD2-C 3.47Å; Y145-H151 PolarHBondContact O-N 2.81Å; Y145-W152 HydrophobicContact CD2-CB 3.66Å; Y145-W152 AromaticContact CD2-CE3 3.93Å; Y145-W152 HydrophobicContact CD2-CE3 3.93Å; Y145-W152 HydrophobicContact CE2-CB 3.97Å; Y145-W152 AromaticContact CG-CE3 3.9Å; Y145-W152 HydrophobicContact CG-CE3 3.9Å; Y145-C238 HydrophobicContact CD2-CB 4.49Å; Y145-C238 HydrophobicContact CE2-CB 4.13Å; Y145-C238 PolarHBondContact OH-N 3.25Å; Y145-D240 WeakPolarHBondContact CE1-OD2 3.4Å; Y145-D240 VanDerWaalsContact CZ-OD2 3.31Å; Y145-D240 PolarHBondContact OH-OD2 3.43Å
146	H	93.9	Very high	94.8	Very high	3 Å²	3	42.6 Å²	42.6	1%	0.014	24%	0.24	C	C	.	.	H	α-helix	trans	-69.5	-35.9	-179.9	-66.9	-50.2	0	0	0	112.5	P86 V90 P91 Y94 R142 L143 G149 Q150	P86-H146 WeakPolarHBondContact O-CB 3.46Å; P86-H146 PolarHBondContact O-ND1 3.33Å; V90-H146 WeakPolarHBondContact CG1-NE2 3.3Å; P91-H146 HydrophobicContact CB-CB 4.03Å; P91-H146 HydrophobicContact CG-CB 3.97Å; Y94-H146 AromaticContact CD2-CD2 3.97Å; Y94-H146 AromaticContact CE2-CD2 3.71Å; Y94-H146 AromaticContact CE2-NE2 3.57Å; R142-H146 PolarHBondContact O-CD2 3.25Å; R142-H146 PolarHBondContact O-N 3.01Å; L143-H146 PolarHBondContact O-N 2.98Å; H146-G149 PolarHBondContact O-N 3.49Å; H146-Q150 PolarHBondContact CE1-OE1 3.28Å; H146-Q150 PolarHBondContact ND1-OE1 2.81Å
147	L	94	Very high	94.9	Very high	113 Å²	113	46 Å²	46	59%	0.592	27%	0.268	S	S	*	.	H	α-helix	trans	-71.2	-31.3	177.3	-69.6	176.7	0	0	0	113.2	P91 L143 A144 G149	P91-L147 HydrophobicContact CB-CD2 4.02Å; P91-L147 HydrophobicContact CB-CG 4.19Å; P91-L147 HydrophobicContact CG-CD2 4.31Å; L143-L147 HydrophobicContact CD1-CD1 3.97Å; L143-L147 HydrophobicContact CD1-CG 4.22Å; L143-L147 HydrophobicContact CG-CD1 3.86Å; L143-L147 HydrophobicContact CG-CG 4.46Å; L143-L147 WeakPolarHBondContact O-CB 3.44Å; L143-L147 VanDerWaalsContact O-CG 3.27Å; L143-L147 WeakPolarHBondContact O-CG 3.3Å; L143-L147 PolarHBondContact O-N 2.96Å; A144-L147 PolarHBondContact O-N 2.89Å; L147-G149 PolarHBondContact O-N 3.2Å
148	H	93.9	Very high	95.1	Very high	123 Å²	123	42 Å²	42	57%	0.569	25%	0.252	S	S	*	.	T	Hydrogen-bonded Turn	trans	-81.9	22.3	169.3	-65	154.7	0	0	0	113.1	A144 Y145 H151	A144-H148 WeakPolarHBondContact O-CB 3.46Å; A144-H148 PolarHBondContact O-N 2.99Å; A144-H148 PolarHBondContact O-ND1 2.84Å; Y145-H148 PolarHBondContact O-N 3.15Å; H148-H151 HydrophobicContact CB-CB 4.47Å
149	G	91	Very high	95.2	Very high	23 Å²	23	40.8 Å²	40.8	24%	0.237	25%	0.245	C	C	.	.	T	Hydrogen-bonded Turn	trans	65.9	47.1	174.3	0	0	0	0	0	113.3	H146 L147 Q235	H146-G149 PolarHBondContact O-N 3.49Å; L147-G149 PolarHBondContact O-N 3.2Å; G149-Q235 PolarHBondContact O-NE2 3.18Å
150	Q	91.6	Very high	95.3	Very high	0 Å²	0	43.8 Å²	43.8	0%	0	26%	0.256	C	S	.	.	S	Bend	trans	65.1	36.1	-179.3	-39.1	-51.5	-36.4	0	0	113.9	L81 L82 P86 Y145 H146 L237	L81-Q150 HydrophobicContact CG-CG 4.38Å; L82-Q150 HydrophobicContact CD2-CB 4.37Å; L82-Q150 HydrophobicContact CD2-CG 4.06Å; P86-Q150 VanDerWaalsContact C-NE2 3.26Å; P86-Q150 PolarHBondContact O-NE2 2.95Å; P86-Q150 VanDerWaalsContact O-NE2 3.09Å; Y145-Q150 HydrophobicContact CE2-CB 4.24Å; Y145-Q150 WeakPolarHBondContact CE2-O 3.28Å; Y145-Q150 WeakPolarHBondContact O-CA 3.45Å; Y145-Q150 PolarHBondContact O-N 3.1Å; H146-Q150 PolarHBondContact CE1-OE1 3.28Å; H146-Q150 PolarHBondContact ND1-OE1 2.81Å; Q150-L237 HydrophobicContact CB-CD2 4.17Å; Q150-L237 WeakPolarHBondContact O-CD2 3.27Å
151	H	95.4	Very high	95.3	Very high	67 Å²	67	46.8 Å²	46.8	31%	0.31	27%	0.266	S	S	.	.			trans	-111.6	123.2	172.6	179.9	101	0	0	0	110.7	Y145 H148 P153 D234 M236	Y145-H151 VanDerWaalsContact CD2-C 3.47Å; Y145-H151 PolarHBondContact O-N 2.81Å; H148-H151 HydrophobicContact CB-CB 4.47Å; H151-P153 VanDerWaalsContact O-CD 3.28Å; H151-P153 WeakPolarHBondContact O-CD 3.29Å; H151-D234 PolarHBondContact CE1-O 3.34Å; H151-D234 VanDerWaalsContact CE1-O 3.28Å; H151-D234 PolarHBondContact ND1-O 2.85Å; H151-M236 CarbonylContact C-O 3.55Å; H151-M236 PolarHBondContact ND1-N 2.86Å
152	W	96.6	Very high	95.3	Very high	2 Å²	2	45.3 Å²	45.3	1%	0.008	26%	0.258	C	S	.	.			trans	-101.5	101.8	-175.5	-177.3	-92.2	0	0	0	111.8	P141 Y145 F154 G155 A158 C159 A162 M236 C238	P141-W152 HydrophobicContact CB-CH2 3.78Å; P141-W152 HydrophobicContact CB-CZ3 4.27Å; Y145-W152 HydrophobicContact CD2-CB 3.66Å; Y145-W152 AromaticContact CD2-CE3 3.93Å; Y145-W152 HydrophobicContact CD2-CE3 3.93Å; Y145-W152 HydrophobicContact CE2-CB 3.97Å; Y145-W152 AromaticContact CG-CE3 3.9Å; Y145-W152 HydrophobicContact CG-CE3 3.9Å; W152-F154 HydrophobicContact CD2-CD2 4.06Å; W152-F154 AromaticContact CE2-CD2 3.81Å; W152-F154 HydrophobicContact CE3-CD2 4.23Å; W152-F154 AromaticContact CH2-CD2 3.88Å; W152-F154 HydrophobicContact CH2-CD2 3.88Å; W152-F154 HydrophobicContact CZ2-CB 3.79Å; W152-F154 AromaticContact CZ2-CD2 3.72Å; W152-F154 HydrophobicContact CZ2-CD2 3.72Å; W152-F154 HydrophobicContact CZ2-CG 4.19Å; W152-F154 HydrophobicContact CZ3-CD2 4.14Å; W152-G155 PolarHBondContact NE1-O 3.35Å; W152-A158 VanDerWaalsContact CZ2-C 3.49Å; W152-A158 HydrophobicContact CZ2-CB 3.88Å; W152-C159 HydrophobicContact CD2-CB 4.35Å; W152-C159 HydrophobicContact CZ2-CB 4.22Å; W152-A162 HydrophobicContact CH2-CB 3.8Å; W152-A162 HydrophobicContact CZ2-CB 4.42Å; W152-M236 VanDerWaalsContact CB-O 3.31Å; W152-M236 WeakPolarHBondContact CB-O 3.39Å; W152-M236 PolarHBondContact N-O 2.84Å; W152-C238 HydrophobicContact CB-CB 3.79Å; W152-C238 HydrophobicContact CD2-CB 3.68Å; W152-C238 HydrophobicContact CE3-CB 3.75Å; W152-C238 HydrophobicContact CG-CB 3.68Å
153	P	95.5	Very high	95.4	Very high	70 Å²	70	44.9 Å²	44.9	46%	0.455	26%	0.256	S	S	.	.	T	Hydrogen-bonded Turn	trans	-86.3	-10.1	-175.3	35.1	-37.8	0	0	0	114.1	H151 G155	H151-P153 VanDerWaalsContact O-CD 3.28Å; H151-P153 WeakPolarHBondContact O-CD 3.29Å; P153-G155 VanDerWaalsContact C-N 3.31Å; P153-G155 PolarHBondContact O-N 3.47Å
154	F	96.4	Very high	95.4	Very high	99 Å²	99	43.3 Å²	43.3	43%	0.434	25%	0.249	S	C	.	.	T	Hydrogen-bonded Turn	trans	-86.5	2.2	-168.6	-49	-75	0	0	0	114.3	P141 A144 W152 A158	P141-F154 HydrophobicContact CB-CD2 4.11Å; P141-F154 HydrophobicContact CB-CE2 3.89Å; P141-F154 HydrophobicContact CB-CZ 4.4Å; A144-F154 HydrophobicContact CB-CE2 4.18Å; A144-F154 HydrophobicContact CB-CZ 4.04Å; W152-F154 HydrophobicContact CD2-CD2 4.06Å; W152-F154 AromaticContact CE2-CD2 3.81Å; W152-F154 HydrophobicContact CE3-CD2 4.23Å; W152-F154 AromaticContact CH2-CD2 3.88Å; W152-F154 HydrophobicContact CH2-CD2 3.88Å; W152-F154 HydrophobicContact CZ2-CB 3.79Å; W152-F154 AromaticContact CZ2-CD2 3.72Å; W152-F154 HydrophobicContact CZ2-CD2 3.72Å; W152-F154 HydrophobicContact CZ2-CG 4.19Å; W152-F154 HydrophobicContact CZ3-CD2 4.14Å; F154-A158 HydrophobicContact CB-CB 3.69Å; F154-A158 VanDerWaalsContact O-CB 3.27Å; F154-A158 WeakPolarHBondContact O-CB 3.41Å
155	G	96.4	Very high	95.5	Very high	30 Å²	30	43.9 Å²	43.9	31%	0.309	25%	0.253	S	S	.	.	H	α-helix	trans	75.1	169.9	-180	0	0	0	0	0	115.1	W152 P153 A157 A158 C159	W152-G155 PolarHBondContact NE1-O 3.35Å; P153-G155 VanDerWaalsContact C-N 3.31Å; P153-G155 PolarHBondContact O-N 3.47Å; G155-A157 PolarHBondContact O-N 2.82Å; G155-A158 PolarHBondContact O-N 3.34Å; G155-C159 PolarHBondContact O-N 3.47Å; G155-C159 VanDerWaalsContact O-N 3.12Å
156	E	96.3	Very high	95.4	Very high	43 Å²	43	44.1 Å²	44.1	20%	0.201	25%	0.254	C	S	.	.	H	α-helix	trans	-59.3	-47.1	-169	172.9	59.9	-176.4	0	0	114.1	A158 C159 R160 R225 Q226 T227	E156-A158 VanDerWaalsContact C-N 3.31Å; E156-A158 PolarHBondContact O-N 3.01Å; E156-C159 WeakPolarHBondContact O-CB 3.41Å; E156-C159 PolarHBondContact O-N 3.14Å; E156-C159 VanDerWaalsContact O-N 3.13Å; E156-R160 PolarHBondContact O-N 2.92Å; E156-R160 IonicContact OE1-CZ 2.85Å; E156-R160 IonicContact OE1-NE 2.85Å; E156-R160 PolarHBondContact OE1-NE 2.8Å; E156-R160 IonicContact OE1-NH2 4Å; E156-R160 PolarHBondContact OE1-NH2 3.18Å; E156-R225 WeakPolarHBondContact OE1-CA 3.43Å; E156-R225 WeakPolarHBondContact OE1-CG 3.32Å; E156-Q226 PolarHBondContact OE1-N 3.49Å; E156-Q226 PolarHBondContact OE2-N 2.98Å; E156-T227 VanDerWaalsContact OE2-CB 3.23Å; E156-T227 WeakPolarHBondContact OE2-CB 3.45Å; E156-T227 VanDerWaalsContact OE2-CG2 3.31Å; E156-T227 WeakPolarHBondContact OE2-CG2 3.38Å; E156-T227 PolarHBondContact OE2-N 3.48Å; E156-T227 PolarHBondContact OE2-OG1 3.41Å
157	A	96.5	Very high	95.5	Very high	75 Å²	75	44 Å²	44	62%	0.62	25%	0.254	S	S	*	.	H	α-helix	trans	-61.5	-40.1	-178.4	0	0	0	0	0	111.9	G155 M161	G155-A157 PolarHBondContact O-N 2.82Å; A157-M161 WeakPolarHBondContact O-CB 3.38Å; A157-M161 VanDerWaalsContact O-CG 3.24Å; A157-M161 WeakPolarHBondContact O-CG 3.43Å; A157-M161 PolarHBondContact O-N 3.05Å
158	A	96.7	Very high	95.6	Very high	36 Å²	36	39.3 Å²	39.3	30%	0.298	23%	0.233	S	C	.	.	H	α-helix	trans	-68.1	-36.7	176	0	0	0	0	0	111.9	W152 F154 G155 E156 M161 A162	W152-A158 VanDerWaalsContact CZ2-C 3.49Å; W152-A158 HydrophobicContact CZ2-CB 3.88Å; F154-A158 HydrophobicContact CB-CB 3.69Å; F154-A158 VanDerWaalsContact O-CB 3.27Å; F154-A158 WeakPolarHBondContact O-CB 3.41Å; G155-A158 PolarHBondContact O-N 3.34Å; E156-A158 VanDerWaalsContact C-N 3.31Å; E156-A158 PolarHBondContact O-N 3.01Å; A158-M161 PolarHBondContact O-N 2.71Å; A158-A162 VanDerWaalsContact O-CB 3.26Å; A158-A162 WeakPolarHBondContact O-CB 3.27Å; A158-A162 PolarHBondContact O-N 3.43Å
159	C	97.4	Very high	95.6	Very high	0 Å²	0	33.9 Å²	33.9	0%	0	21%	0.208	C	C	.	.	H	α-helix	trans	-60.5	-51.8	174.9	177.1	0	0	0	0	110.7	W152 G155 E156 M161 A162 T163 T227 C238	W152-C159 HydrophobicContact CD2-CB 4.35Å; W152-C159 HydrophobicContact CZ2-CB 4.22Å; G155-C159 PolarHBondContact O-N 3.47Å; G155-C159 VanDerWaalsContact O-N 3.12Å; E156-C159 WeakPolarHBondContact O-CB 3.41Å; E156-C159 PolarHBondContact O-N 3.14Å; E156-C159 VanDerWaalsContact O-N 3.13Å; C159-M161 VanDerWaalsContact C-N 3.35Å; C159-M161 PolarHBondContact O-N 2.91Å; C159-A162 PolarHBondContact O-N 2.84Å; C159-T163 PolarHBondContact O-N 3.44Å; C159-T163 PolarHBondContact O-OG1 3.37Å; C159-T163 VanDerWaalsContact O-OG1 3.04Å; C159-T227 HydrophobicContact CB-CG2 3.51Å; C159-C238 VanDerWaalsContact CA-SG 3.5Å; C159-C238 HydrophobicContact CB-CB 4Å; C159-C238 WeakPolarHBondContact CB-SG 3.18Å; C159-C238 WeakPolarHBondContact SG-CA 3.16Å; C159-C238 WeakPolarHBondContact SG-CB 3.35Å; C159-C238 CovalentContact SG-SG 2.04Å; C159-C238 PolarHBondContact SG-SG 3.33Å
160	R	97	Very high	95.8	Very high	63 Å²	63	33 Å²	33	24%	0.238	20%	0.198	C	C	.	.	H	α-helix	trans	-57.6	-45.6	177.2	-64.8	-170.3	-158	-168.4	-3.2	112.4	E156 A164 T222 L223 Q224 Q226	E156-R160 PolarHBondContact O-N 2.92Å; E156-R160 IonicContact OE1-CZ 2.85Å; E156-R160 IonicContact OE1-NE 2.85Å; E156-R160 PolarHBondContact OE1-NE 2.8Å; E156-R160 IonicContact OE1-NH2 4Å; E156-R160 PolarHBondContact OE1-NH2 3.18Å; R160-A164 WeakPolarHBondContact O-CB 3.1Å; R160-A164 PolarHBondContact O-N 3.18Å; R160-T222 WeakPolarHBondContact CD-O 3.43Å; R160-T222 PolarHBondContact NH1-O 3.09Å; R160-T222 VanDerWaalsContact NH1-O 3.08Å; R160-L223 PolarHBondContact NH1-O 2.81Å; R160-Q224 WeakPolarHBondContact CD-O 3.27Å; R160-Q224 VanDerWaalsContact CZ-O 3.22Å; R160-Q224 PolarHBondContact NE-O 3.47Å; R160-Q224 VanDerWaalsContact NE-O 3.07Å; R160-Q226 HydrophobicContact CG-CB 4.49Å; R160-Q226 HydrophobicContact CG-CG 4.27Å
161	M	96.4	Very high	96	Very high	121 Å²	121	33 Å²	33	60%	0.596	20%	0.198	S	C	*	.	H	α-helix	trans	-63.4	-44.4	178.1	-73.9	-109.8	63.1	0	0	112	A157 A158 C159 A164 A165	A157-M161 WeakPolarHBondContact O-CB 3.38Å; A157-M161 VanDerWaalsContact O-CG 3.24Å; A157-M161 WeakPolarHBondContact O-CG 3.43Å; A157-M161 PolarHBondContact O-N 3.05Å; A158-M161 PolarHBondContact O-N 2.71Å; C159-M161 VanDerWaalsContact C-N 3.35Å; C159-M161 PolarHBondContact O-N 2.91Å; M161-A164 PolarHBondContact O-N 3.4Å; M161-A165 WeakPolarHBondContact O-CB 3.22Å; M161-A165 PolarHBondContact O-N 2.7Å
162	A	96	Very high	96	Very high	11 Å²	11	30 Å²	30	9%	0.091	18%	0.184	C	C	.	.	H	α-helix	trans	-66.1	-41.3	178.6	0	0	0	0	0	112.1	W152 A158 C159 L166	W152-A162 HydrophobicContact CH2-CB 3.8Å; W152-A162 HydrophobicContact CZ2-CB 4.42Å; A158-A162 VanDerWaalsContact O-CB 3.26Å; A158-A162 WeakPolarHBondContact O-CB 3.27Å; A158-A162 PolarHBondContact O-N 3.43Å; C159-A162 PolarHBondContact O-N 2.84Å; A162-L166 WeakPolarHBondContact O-CB 3.38Å; A162-L166 PolarHBondContact O-N 2.81Å
163	T	95.4	Very high	96	Very high	0 Å²	0	29.9 Å²	29.9	0%	0	18%	0.184	C	C	.	.	H	α-helix	trans	-61.7	-53.4	172.1	-57.3	0	0	0	0	111.1	R142 C159 A165 L166 Y167 L221 Q226 H239	R142-T163 PolarHBondContact NH2-OG1 2.91Å; C159-T163 PolarHBondContact O-N 3.44Å; C159-T163 PolarHBondContact O-OG1 3.37Å; C159-T163 VanDerWaalsContact O-OG1 3.04Å; T163-A165 VanDerWaalsContact C-N 3.29Å; T163-A165 PolarHBondContact O-N 3.14Å; T163-L166 PolarHBondContact O-N 3.14Å; T163-Y167 HydrophobicContact CG2-CD2 3.86Å; T163-Y167 HydrophobicContact CG2-CE2 3.79Å; T163-Y167 WeakPolarHBondContact O-CD2 3.4Å; T163-Y167 PolarHBondContact O-N 2.96Å; T163-Y167 VanDerWaalsContact O-N 3.11Å; T163-L221 HydrophobicContact CG2-CD1 4.43Å; T163-Q226 PolarHBondContact OG1-OE1 3.4Å; T163-H239 HydrophobicContact CG2-CB 4.38Å
164	A	96.4	Very high	96	Very high	6 Å²	6	26.5 Å²	26.5	5%	0.05	16%	0.162	C	C	.	.	H	α-helix	trans	-59.9	-38.6	-178.4	0	0	0	0	0	112.4	R160 M161 G168 A218 L221 T222	R160-A164 WeakPolarHBondContact O-CB 3.1Å; R160-A164 PolarHBondContact O-N 3.18Å; M161-A164 PolarHBondContact O-N 3.4Å; A164-G168 WeakPolarHBondContact O-CA 3.2Å; A164-G168 PolarHBondContact O-N 3.32Å; A164-A218 HydrophobicContact CB-CB 4.25Å; A164-A218 WeakPolarHBondContact O-CB 3.17Å; A164-L221 HydrophobicContact CB-CB 4.34Å; A164-T222 HydrophobicContact CB-CG2 3.52Å
165	A	96.3	Very high	96	Very high	36 Å²	36	23.4 Å²	23.4	30%	0.298	15%	0.149	S	C	.	.	H	α-helix	trans	-74.1	-32.3	177.7	0	0	0	0	0	113.3	V138 M161 T163 G168 H169	V138-A165 HydrophobicContact CB-CB 4.43Å; V138-A165 HydrophobicContact CG1-CB 4Å; V138-A165 HydrophobicContact CG2-CB 3.55Å; M161-A165 WeakPolarHBondContact O-CB 3.22Å; M161-A165 PolarHBondContact O-N 2.7Å; T163-A165 VanDerWaalsContact C-N 3.29Å; T163-A165 PolarHBondContact O-N 3.14Å; A165-G168 PolarHBondContact O-N 3.49Å; A165-H169 WeakPolarHBondContact O-CB 3.23Å; A165-H169 PolarHBondContact O-N 3.4Å
166	L	95.3	Very high	96	Very high	5 Å²	5	22 Å²	22	3%	0.026	14%	0.135	C	C	.	.	H	α-helix	trans	-63.9	-50	173.5	-179.6	64.6	0	0	0	111.6	L135 L139 A162 T163 H169 M170 L336 T340	L135-L166 HydrophobicContact CD1-CD1 3.73Å; L139-L166 HydrophobicContact CD2-CD1 4.32Å; A162-L166 WeakPolarHBondContact O-CB 3.38Å; A162-L166 PolarHBondContact O-N 2.81Å; T163-L166 PolarHBondContact O-N 3.14Å; L166-H169 PolarHBondContact O-N 2.91Å; L166-M170 PolarHBondContact O-N 3.19Å; L166-M170 VanDerWaalsContact O-N 3.17Å; L166-L336 HydrophobicContact CD2-CD2 4.09Å; L166-T340 HydrophobicContact CD1-CG2 3.77Å
167	Y	95	Very high	95.9	Very high	1 Å²	1	20 Å²	20	0%	0.004	13%	0.126	C	C	.	.	H	α-helix	trans	-68.5	-36.4	174.4	-76.3	-82.7	0	0	0	112.3	T163 H169 M170 Y171 L221 H239 F255 L258 L313 Y332	T163-Y167 HydrophobicContact CG2-CD2 3.86Å; T163-Y167 HydrophobicContact CG2-CE2 3.79Å; T163-Y167 WeakPolarHBondContact O-CD2 3.4Å; T163-Y167 PolarHBondContact O-N 2.96Å; T163-Y167 VanDerWaalsContact O-N 3.11Å; Y167-H169 VanDerWaalsContact C-N 3.34Å; Y167-H169 PolarHBondContact O-N 2.97Å; Y167-M170 HydrophobicContact CD1-CE 3.78Å; Y167-M170 HydrophobicContact CE1-CE 4.22Å; Y167-M170 PolarHBondContact O-N 3.17Å; Y167-Y171 AromaticContact CD1-CE2 3.84Å; Y167-Y171 HydrophobicContact CD1-CE2 3.84Å; Y167-Y171 HydrophobicContact CG-CE2 4.42Å; Y167-Y171 WeakPolarHBondContact O-CD2 3.22Å; Y167-Y171 PolarHBondContact O-N 3.23Å; Y167-L221 HydrophobicContact CD2-CD1 3.47Å; Y167-L221 VanDerWaalsContact CD2-CD1 3.47Å; Y167-L221 HydrophobicContact CE2-CD1 4.21Å; Y167-L221 HydrophobicContact CG-CD1 3.72Å; Y167-H239 AromaticContact CE2-NE2 3.66Å; Y167-H239 PolarHBondContact OH-NE2 3.35Å; Y167-F255 HydrophobicContact CE1-CD1 4.36Å; Y167-F255 AromaticContact CE1-CE1 3.87Å; Y167-F255 HydrophobicContact CE1-CE1 3.87Å; Y167-F255 HydrophobicContact CE2-CE1 4.04Å; Y167-F255 HydrophobicContact CE2-CZ 4.48Å; Y167-F255 AromaticContact CZ-CE1 3.51Å; Y167-F255 VanDerWaalsContact OH-CE1 3.28Å; Y167-F255 WeakPolarHBondContact OH-CE1 3.3Å; Y167-L258 HydrophobicContact CD1-CD2 4.44Å; Y167-L313 HydrophobicContact CE1-CD1 4.43Å; Y167-L313 HydrophobicContact CE1-CD2 4.03Å; Y167-Y332 PolarHBondContact OH-OH 3.1Å
168	G	95.8	Very high	95.9	Very high	14 Å²	14	17.2 Å²	17.2	14%	0.144	10%	0.103	C	C	.	.	H	α-helix	trans	-62	-38.4	176	0	0	0	0	0	112.9	A164 A165 G172	A164-G168 WeakPolarHBondContact O-CA 3.2Å; A164-G168 PolarHBondContact O-N 3.32Å; A165-G168 PolarHBondContact O-N 3.49Å; G168-G172 WeakPolarHBondContact O-CA 3.29Å; G168-G172 PolarHBondContact O-N 3.36Å
169	H	94.9	Very high	95.8	Very high	9 Å²	9	15.9 Å²	15.9	4%	0.042	9%	0.091	C	C	.	.	H	α-helix	trans	-62.1	-52.2	168	168.3	-96.1	0	0	0	111.1	S131 D132 L135 A165 L166 Y167 Y171 G172 S173	S131-H169 PolarHBondContact O-CD2 2.8Å; D132-H169 IonicContact OD1-CD2 3.54Å; D132-H169 IonicContact OD1-CE1 2.92Å; D132-H169 IonicContact OD1-NE2 3.9Å; D132-H169 PolarHBondContact OD1-NE2 2.87Å; L135-H169 HydrophobicContact CB-CB 4.11Å; L135-H169 HydrophobicContact CD1-CB 4.33Å; L135-H169 VanDerWaalsContact CD2-CE1 3.41Å; L135-H169 WeakPolarHBondContact CD2-CE1 3.26Å; A165-H169 WeakPolarHBondContact O-CB 3.23Å; A165-H169 PolarHBondContact O-N 3.4Å; L166-H169 PolarHBondContact O-N 2.91Å; Y167-H169 VanDerWaalsContact C-N 3.34Å; Y167-H169 PolarHBondContact O-N 2.97Å; H169-Y171 PolarHBondContact O-N 3.41Å; H169-G172 PolarHBondContact O-N 2.71Å; H169-S173 VanDerWaalsContact O-CB 3.28Å; H169-S173 WeakPolarHBondContact O-CB 3.38Å; H169-S173 PolarHBondContact O-N 3Å
170	M	94.6	Very high	95.5	Very high	6 Å²	6	16.6 Å²	16.6	3%	0.03	10%	0.096	C	C	.	.	H	α-helix	trans	-55	-50.5	-176.1	-174.7	172.9	61.6	0	0	111.7	L166 Y167 V174 F306 L336	L166-M170 PolarHBondContact O-N 3.19Å; L166-M170 VanDerWaalsContact O-N 3.17Å; Y167-M170 HydrophobicContact CD1-CE 3.78Å; Y167-M170 HydrophobicContact CE1-CE 4.22Å; Y167-M170 PolarHBondContact O-N 3.17Å; M170-V174 VanDerWaalsContact O-CG2 3.3Å; M170-V174 WeakPolarHBondContact O-CG2 3.33Å; M170-V174 PolarHBondContact O-N 3.05Å; M170-F306 HydrophobicContact CG-CD1 3.56Å; M170-F306 HydrophobicContact CG-CE1 3.86Å; M170-F306 HydrophobicContact SD-CD1 4.17Å; M170-L336 HydrophobicContact SD-CD1 4.33Å
171	Y	95.6	Very high	95.3	Very high	0 Å²	0	14.1 Å²	14.1	0%	0	9%	0.088	C	C	.	.	H	α-helix	trans	-75.6	-33.5	179.4	-57.5	-50.8	0	0	0	113	Y167 H169 V174 L175 L217 L258 G262 C263 N310	Y167-Y171 AromaticContact CD1-CE2 3.84Å; Y167-Y171 HydrophobicContact CD1-CE2 3.84Å; Y167-Y171 HydrophobicContact CG-CE2 4.42Å; Y167-Y171 WeakPolarHBondContact O-CD2 3.22Å; Y167-Y171 PolarHBondContact O-N 3.23Å; H169-Y171 PolarHBondContact O-N 3.41Å; Y171-V174 PolarHBondContact O-N 2.87Å; Y171-L175 WeakPolarHBondContact O-CB 3.32Å; Y171-L175 WeakPolarHBondContact O-CD1 3.43Å; Y171-L175 WeakPolarHBondContact O-CG 3.18Å; Y171-L175 PolarHBondContact O-N 3.03Å; Y171-L217 HydrophobicContact CG-CD1 4.47Å; Y171-L258 HydrophobicContact CD2-CG 4.4Å; Y171-L258 WeakPolarHBondContact CE1-O 3.38Å; Y171-L258 HydrophobicContact CE2-CB 3.72Å; Y171-L258 HydrophobicContact CE2-CD2 3.8Å; Y171-L258 HydrophobicContact CE2-CG 3.68Å; Y171-G262 VanDerWaalsContact CD1-CA 3.46Å; Y171-G262 WeakPolarHBondContact CD1-O 3.33Å; Y171-C263 HydrophobicContact CE1-CB 4.2Å; Y171-N310 WeakPolarHBondContact CE1-OD1 3.5Å; Y171-N310 PolarHBondContact OH-OD1 3.21Å
172	G	96.4	Very high	95.1	Very high	2 Å²	2	11.1 Å²	11.1	2%	0.021	7%	0.074	C	C	.	.	H	α-helix	trans	-62.6	-46.6	174	0	0	0	0	0	112.5	G168 H169 L175 L176	G168-G172 WeakPolarHBondContact O-CA 3.29Å; G168-G172 PolarHBondContact O-N 3.36Å; H169-G172 PolarHBondContact O-N 2.71Å; G172-L175 PolarHBondContact O-N 2.71Å; G172-L176 WeakPolarHBondContact O-CB 3.25Å; G172-L176 VanDerWaalsContact O-CG 3.22Å; G172-L176 WeakPolarHBondContact O-CG 3.43Å; G172-L176 PolarHBondContact O-N 3.04Å
173	S	95.9	Very high	94.8	Very high	0 Å²	0	11 Å²	11	0%	0	7%	0.072	C	C	.	.	H	α-helix	trans	-59.2	-50.8	174.7	179.5	0	0	0	0	110.8	H169 L175 L176 L177	H169-S173 VanDerWaalsContact O-CB 3.28Å; H169-S173 WeakPolarHBondContact O-CB 3.38Å; H169-S173 PolarHBondContact O-N 3Å; S173-L175 PolarHBondContact O-N 3.1Å; S173-L176 PolarHBondContact O-N 3.46Å; S173-L176 VanDerWaalsContact O-N 3.15Å; S173-L177 WeakPolarHBondContact O-CB 3.24Å; S173-L177 VanDerWaalsContact O-CG 3.28Å; S173-L177 WeakPolarHBondContact O-CG 3.46Å; S173-L177 PolarHBondContact O-N 3.26Å
174	V	95.8	Very high	94.4	Very high	0 Å²	0	13.4 Å²	13.4	0%	0	8%	0.081	C	C	.	.	H	α-helix	trans	-56.2	-45.2	176	169.8	0	0	0	0	112.6	M170 Y171 L177 A178 G262 P266 F306	M170-V174 VanDerWaalsContact O-CG2 3.3Å; M170-V174 WeakPolarHBondContact O-CG2 3.33Å; M170-V174 PolarHBondContact O-N 3.05Å; Y171-V174 PolarHBondContact O-N 2.87Å; V174-L177 PolarHBondContact O-N 2.89Å; V174-A178 WeakPolarHBondContact O-CB 3.26Å; V174-A178 PolarHBondContact O-N 2.86Å; V174-G262 WeakPolarHBondContact CG1-O 3.49Å; V174-P266 HydrophobicContact CG1-CB 3.41Å; V174-P266 VanDerWaalsContact CG1-CB 3.41Å; V174-P266 HydrophobicContact CG1-CG 3.96Å; V174-F306 HydrophobicContact CG2-CB 4.08Å; V174-F306 HydrophobicContact CG2-CD1 4.09Å; V174-F306 HydrophobicContact CG2-CD2 3.19Å; V174-F306 HydrophobicContact CG2-CE1 4.32Å; V174-F306 HydrophobicContact CG2-CE2 3.49Å; V174-F306 VanDerWaalsContact CG2-CE2 3.49Å; V174-F306 HydrophobicContact CG2-CG 3.52Å; V174-F306 HydrophobicContact CG2-CZ 4.03Å
175	L	96.8	Very high	94	Very high	33 Å²	33	15.6 Å²	15.6	17%	0.173	9%	0.088	C	C	.	.	H	α-helix	trans	-66.3	-37.9	178.2	-72.3	165.5	0	0	0	112.4	Y171 G172 S173 A178 A179 A210 P266	Y171-L175 WeakPolarHBondContact O-CB 3.32Å; Y171-L175 WeakPolarHBondContact O-CD1 3.43Å; Y171-L175 WeakPolarHBondContact O-CG 3.18Å; Y171-L175 PolarHBondContact O-N 3.03Å; G172-L175 PolarHBondContact O-N 2.71Å; S173-L175 PolarHBondContact O-N 3.1Å; L175-A178 PolarHBondContact O-N 2.87Å; L175-A179 PolarHBondContact O-N 3.42Å; L175-A210 HydrophobicContact CB-CB 3.84Å; L175-P266 HydrophobicContact CD2-CG 3.72Å; L175-P266 HydrophobicContact CG-CG 4.42Å
176	L	96.1	Very high	93.7	Very high	2 Å²	2	14.8 Å²	14.8	1%	0.01	8%	0.079	C	C	.	.	H	α-helix	trans	-68.7	-40.6	175.1	-71.9	167.3	0	0	0	111.7	N127 L128 G172 S173 A178 A179 V180 A210	N127-L176 HydrophobicContact CB-CD1 4.26Å; N127-L176 HydrophobicContact CB-CD2 3.82Å; L128-L176 HydrophobicContact CD1-CB 4.19Å; G172-L176 WeakPolarHBondContact O-CB 3.25Å; G172-L176 VanDerWaalsContact O-CG 3.22Å; G172-L176 WeakPolarHBondContact O-CG 3.43Å; G172-L176 PolarHBondContact O-N 3.04Å; S173-L176 PolarHBondContact O-N 3.46Å; S173-L176 VanDerWaalsContact O-N 3.15Å; L176-A178 VanDerWaalsContact C-N 3.33Å; L176-A178 PolarHBondContact O-N 3.33Å; L176-A179 WeakPolarHBondContact O-CB 3.37Å; L176-A179 PolarHBondContact O-N 2.9Å; L176-V180 WeakPolarHBondContact O-CG2 3.38Å; L176-V180 PolarHBondContact O-N 3.49Å; L176-A210 HydrophobicContact CD2-CB 3.9Å; L176-A210 HydrophobicContact CG-CB 4.05Å
177	L	94.3	Very high	93.3	Very high	0 Å²	0	15.8 Å²	15.8	0%	0	9%	0.088	C	C	.	.	H	α-helix	trans	-65.6	-34.2	173.8	-67.6	173.1	0	0	0	112.1	L128 S173 V174 V180 S181 M270 V298 A302 F306 I349	L128-L177 HydrophobicContact CD1-CD2 4.24Å; L128-L177 HydrophobicContact CD1-CG 4.23Å; L128-L177 HydrophobicContact CD2-CD2 3.64Å; L128-L177 HydrophobicContact CD2-CG 4.5Å; S173-L177 WeakPolarHBondContact O-CB 3.24Å; S173-L177 VanDerWaalsContact O-CG 3.28Å; S173-L177 WeakPolarHBondContact O-CG 3.46Å; S173-L177 PolarHBondContact O-N 3.26Å; V174-L177 PolarHBondContact O-N 2.89Å; L177-V180 PolarHBondContact O-N 2.94Å; L177-S181 WeakPolarHBondContact O-CB 3.26Å; L177-S181 PolarHBondContact O-N 2.89Å; L177-S181 PolarHBondContact O-OG 3.46Å; L177-M270 HydrophobicContact CB-CE 4.03Å; L177-M270 HydrophobicContact CB-SD 4.32Å; L177-V298 HydrophobicContact CB-CG1 4.44Å; L177-V298 HydrophobicContact CD2-CG1 4.06Å; L177-A302 HydrophobicContact CD1-CB 4.22Å; L177-F306 HydrophobicContact CD1-CE2 4.11Å; L177-I349 HydrophobicContact CD2-CD1 3.99Å
178	A	95.4	Very high	92.7	Very high	17 Å²	17	17.5 Å²	17.5	14%	0.14	10%	0.097	C	C	.	.	H	α-helix	trans	-65.5	-41.9	169.8	0	0	0	0	0	112.1	V174 L175 L176 S181 L182 P266 M270	V174-A178 WeakPolarHBondContact O-CB 3.26Å; V174-A178 PolarHBondContact O-N 2.86Å; L175-A178 PolarHBondContact O-N 2.87Å; L176-A178 VanDerWaalsContact C-N 3.33Å; L176-A178 PolarHBondContact O-N 3.33Å; A178-S181 WeakPolarHBondContact O-CB 3.12Å; A178-S181 PolarHBondContact O-N 2.91Å; A178-L182 WeakPolarHBondContact O-CB 3.48Å; A178-L182 PolarHBondContact O-N 2.95Å; A178-P266 HydrophobicContact CB-CB 4.12Å; A178-M270 HydrophobicContact CB-CG 3.84Å; A178-M270 HydrophobicContact CB-SD 4.23Å
179	A	95	Very high	92.3	Very high	7 Å²	7	18.5 Å²	18.5	6%	0.058	10%	0.1	C	C	.	.	H	α-helix	trans	-65.3	-38.7	174.1	0	0	0	0	0	112.9	L124 L175 L176 L182 D183 L206	L124-A179 HydrophobicContact CD2-CB 3.7Å; L175-A179 PolarHBondContact O-N 3.42Å; L176-A179 WeakPolarHBondContact O-CB 3.37Å; L176-A179 PolarHBondContact O-N 2.9Å; A179-L182 PolarHBondContact O-N 2.87Å; A179-D183 PolarHBondContact O-N 3.49Å; A179-L206 HydrophobicContact CB-CB 4.04Å; A179-L206 HydrophobicContact CB-CD1 4.26Å
180	V	92.1	Very high	91.8	Very high	16 Å²	16	20.4 Å²	20.4	10%	0.097	11%	0.109	C	C	.	.	H	α-helix	trans	-61.1	-45.7	170.7	170	0	0	0	0	110.6	L124 L125 L176 L177 L182 D183 R184	L124-V180 HydrophobicContact CB-CG2 3.78Å; L124-V180 HydrophobicContact CD1-CG2 4.39Å; L125-V180 HydrophobicContact CD2-CG2 4.41Å; L176-V180 WeakPolarHBondContact O-CG2 3.38Å; L176-V180 PolarHBondContact O-N 3.49Å; L177-V180 PolarHBondContact O-N 2.94Å; V180-L182 VanDerWaalsContact C-N 3.31Å; V180-L182 PolarHBondContact O-N 2.88Å; V180-D183 PolarHBondContact O-N 2.95Å; V180-R184 WeakPolarHBondContact O-CG 3.3Å; V180-R184 PolarHBondContact O-N 3.42Å
181	S	91.4	Very high	91.2	Very high	11 Å²	11	23.8 Å²	23.8	8%	0.077	13%	0.131	C	C	.	.	H	α-helix	trans	-61.8	-38.6	178.1	-60.5	0	0	0	0	112.2	L177 A178 R184 Y185	L177-S181 WeakPolarHBondContact O-CB 3.26Å; L177-S181 PolarHBondContact O-N 2.89Å; L177-S181 PolarHBondContact O-OG 3.46Å; A178-S181 WeakPolarHBondContact O-CB 3.12Å; A178-S181 PolarHBondContact O-N 2.91Å; S181-R184 PolarHBondContact O-N 3.46Å; S181-Y185 WeakPolarHBondContact O-CB 3.16Å; S181-Y185 PolarHBondContact O-N 3.11Å
182	L	92.2	Very high	90.6	Very high	58 Å²	58	30.7 Å²	30.7	30%	0.304	17%	0.168	S	C	.	.	H	α-helix	trans	-66.8	-43.2	174.5	-179.1	62.1	0	0	0	112.3	A178 A179 V180 R184 Y185 L186 L206	A178-L182 WeakPolarHBondContact O-CB 3.48Å; A178-L182 PolarHBondContact O-N 2.95Å; A179-L182 PolarHBondContact O-N 2.87Å; V180-L182 VanDerWaalsContact C-N 3.31Å; V180-L182 PolarHBondContact O-N 2.88Å; L182-R184 VanDerWaalsContact C-N 3.32Å; L182-R184 PolarHBondContact O-N 2.84Å; L182-Y185 HydrophobicContact CD1-CD1 4.18Å; L182-Y185 PolarHBondContact O-N 2.88Å; L182-L186 HydrophobicContact CD1-CG 4.37Å; L182-L186 HydrophobicContact CG-CD1 4.35Å; L182-L186 WeakPolarHBondContact O-CG 3.11Å; L182-L186 PolarHBondContact O-N 3.21Å; L182-L206 HydrophobicContact CD2-CD1 4.34Å; L182-L206 HydrophobicContact CD2-CD2 4.17Å
183	D	89.8	Confident	89.9	Confident	8 Å²	8	38.1 Å²	38.1	4%	0.043	20%	0.195	C	C	.	.	H	α-helix	trans	-59.6	-42.4	174.3	172.2	78.4	0	0	0	111.8	S121 L124 A179 V180 A187 R198	S121-D183 WeakPolarHBondContact CB-OD2 3.18Å; L124-D183 HydrophobicContact CD1-CB 3.84Å; A179-D183 PolarHBondContact O-N 3.49Å; V180-D183 PolarHBondContact O-N 2.95Å; D183-A187 WeakPolarHBondContact O-CB 3.4Å; D183-A187 PolarHBondContact O-N 3.44Å; D183-R198 VanDerWaalsContact CG-NH2 3.26Å; D183-R198 IonicContact OD1-CZ 3.6Å; D183-R198 IonicContact OD1-NE 2.85Å; D183-R198 PolarHBondContact OD1-NE 3.35Å; D183-R198 IonicContact OD1-NH2 3.21Å; D183-R198 PolarHBondContact OD1-NH2 3.41Å; D183-R198 IonicContact OD2-CZ 3.15Å; D183-R198 IonicContact OD2-NE 2.69Å; D183-R198 IonicContact OD2-NH2 2.67Å; D183-R198 PolarHBondContact OD2-NH2 2.81Å
184	R	87.4	Confident	89.1	Confident	51 Å²	51	38.6 Å²	38.6	19%	0.192	20%	0.199	C	C	.	.	H	α-helix	trans	-63.7	-46.4	174.5	-66.6	-60.8	86.5	168.5	8.2	112.1	S121 V180 S181 L182 L186 A187 L188 R198 T295	S121-R184 VanDerWaalsContact CB-NH2 3.3Å; S121-R184 PolarHBondContact OG-NH2 3.07Å; V180-R184 WeakPolarHBondContact O-CG 3.3Å; V180-R184 PolarHBondContact O-N 3.42Å; S181-R184 PolarHBondContact O-N 3.46Å; L182-R184 VanDerWaalsContact C-N 3.32Å; L182-R184 PolarHBondContact O-N 2.84Å; R184-L186 PolarHBondContact O-N 3.37Å; R184-A187 PolarHBondContact O-N 3.45Å; R184-L188 WeakPolarHBondContact O-CG 3.41Å; R184-L188 PolarHBondContact O-N 3.03Å; R184-R198 VanDerWaalsContact NH2-NH2 3.13Å; R184-T295 HydrophobicContact CB-CG2 3.68Å; R184-T295 HydrophobicContact CG-CG2 3.8Å
185	Y	88.9	Confident	88.3	Confident	51 Å²	51	49.3 Å²	49.3	20%	0.2	24%	0.239	C	C	.	.	H	α-helix	trans	-57.5	-49.1	176.3	166.6	-104.1	0	0	0	111.9	S181 L182 A187 L188 V189 H190 C273 A276	S181-Y185 WeakPolarHBondContact O-CB 3.16Å; S181-Y185 PolarHBondContact O-N 3.11Å; L182-Y185 HydrophobicContact CD1-CD1 4.18Å; L182-Y185 PolarHBondContact O-N 2.88Å; Y185-A187 VanDerWaalsContact C-N 3.32Å; Y185-A187 PolarHBondContact O-N 3.43Å; Y185-L188 PolarHBondContact O-N 3.46Å; Y185-V189 HydrophobicContact CD2-CB 3.91Å; Y185-V189 HydrophobicContact CD2-CG2 3.48Å; Y185-V189 VanDerWaalsContact CD2-CG2 3.48Å; Y185-V189 HydrophobicContact CE2-CB 3.63Å; Y185-V189 HydrophobicContact CE2-CG1 3.76Å; Y185-V189 HydrophobicContact CE2-CG2 3.55Å; Y185-V189 HydrophobicContact CG-CG2 4.48Å; Y185-V189 WeakPolarHBondContact O-CB 3.22Å; Y185-V189 PolarHBondContact O-N 2.96Å; Y185-H190 AromaticContact CE1-CD2 3.75Å; Y185-H190 AromaticContact CE1-NE2 3.89Å; Y185-H190 AromaticContact CZ-CD2 3.66Å; Y185-H190 AromaticContact CZ-NE2 3.46Å; Y185-H190 PolarHBondContact OH-NE2 3.5Å; Y185-C273 HydrophobicContact CG-CB 4.36Å; Y185-A276 HydrophobicContact CD2-CB 4.02Å; Y185-A276 HydrophobicContact CE2-CB 3.45Å; Y185-A276 VanDerWaalsContact CE2-CB 3.45Å
186	L	89.5	Confident	87.5	Confident	20 Å²	20	53.5 Å²	53.5	11%	0.105	27%	0.266	C	S	.	.	H	α-helix	trans	-60	-43.6	177.7	-71	174.2	0	0	0	111.4	L182 R184 L188 H190 A194 L197 R198 L202	L182-L186 HydrophobicContact CD1-CG 4.37Å; L182-L186 HydrophobicContact CG-CD1 4.35Å; L182-L186 WeakPolarHBondContact O-CG 3.11Å; L182-L186 PolarHBondContact O-N 3.21Å; R184-L186 PolarHBondContact O-N 3.37Å; L186-L188 PolarHBondContact O-N 3.31Å; L186-H190 CarbonylContact O-C 3.59Å; L186-H190 PolarHBondContact O-N 3.18Å; L186-A194 WeakPolarHBondContact O-CB 3.17Å; L186-L197 HydrophobicContact CD2-CD1 4.38Å; L186-R198 HydrophobicContact CB-CG 4.25Å; L186-L202 HydrophobicContact CD1-CD2 4.01Å
187	A	86.1	Confident	86.7	Confident	25 Å²	25	57.4 Å²	57.4	21%	0.207	29%	0.286	C	S	.	.	H	α-helix	trans	-62.4	-39.9	179.8	0	0	0	0	0	113.7	D183 R184 Y185	D183-A187 WeakPolarHBondContact O-CB 3.4Å; D183-A187 PolarHBondContact O-N 3.44Å; R184-A187 PolarHBondContact O-N 3.45Å; Y185-A187 VanDerWaalsContact C-N 3.32Å; Y185-A187 PolarHBondContact O-N 3.43Å
188	L	83.4	Confident	86.2	Confident	37 Å²	37	60.5 Å²	60.5	19%	0.194	30%	0.298	C	S	.	.	H	α-helix	trans	-92.9	-39.4	-172.4	-65.4	172.5	0	0	0	113.4	R184 Y185 L186 T277 Y288 A291	R184-L188 WeakPolarHBondContact O-CG 3.41Å; R184-L188 PolarHBondContact O-N 3.03Å; Y185-L188 PolarHBondContact O-N 3.46Å; L186-L188 PolarHBondContact O-N 3.31Å; L188-T277 HydrophobicContact CB-CG2 4.18Å; L188-T277 HydrophobicContact CD1-CG2 3.57Å; L188-Y288 HydrophobicContact CD2-CD1 3.93Å; L188-Y288 HydrophobicContact CD2-CD2 4.15Å; L188-Y288 HydrophobicContact CD2-CE1 4.46Å; L188-Y288 HydrophobicContact CD2-CG 3.76Å; L188-A291 HydrophobicContact CD1-CB 4.04Å; L188-A291 HydrophobicContact CD2-CB 4.28Å
189	V	86.6	Confident	85.7	Confident	35 Å²	35	61.1 Å²	61.1	21%	0.212	31%	0.306	C	S	.	.	H	α-helix	trans	-92.8	-30.9	-173.6	-175	0	0	0	0	112.4	Y185 P191 A280	Y185-V189 HydrophobicContact CD2-CB 3.91Å; Y185-V189 HydrophobicContact CD2-CG2 3.48Å; Y185-V189 VanDerWaalsContact CD2-CG2 3.48Å; Y185-V189 HydrophobicContact CE2-CB 3.63Å; Y185-V189 HydrophobicContact CE2-CG1 3.76Å; Y185-V189 HydrophobicContact CE2-CG2 3.55Å; Y185-V189 HydrophobicContact CG-CG2 4.48Å; Y185-V189 WeakPolarHBondContact O-CB 3.22Å; Y185-V189 PolarHBondContact O-N 2.96Å; V189-P191 VanDerWaalsContact C-CD 3.43Å; V189-A280 HydrophobicContact CB-CB 4.28Å; V189-A280 HydrophobicContact CG1-CB 4.03Å; V189-A280 HydrophobicContact CG2-CB 3.79Å
190	H	85.2	Confident	85.2	Confident	49 Å²	49	65.1 Å²	65.1	23%	0.227	32%	0.323	C	S	.	.			trans	-126.5	53.1	-176.1	-62.5	-83.2	0	0	0	113	Y185 L186 L192 R193 A194	Y185-H190 AromaticContact CE1-CD2 3.75Å; Y185-H190 AromaticContact CE1-NE2 3.89Å; Y185-H190 AromaticContact CZ-CD2 3.66Å; Y185-H190 AromaticContact CZ-NE2 3.46Å; Y185-H190 PolarHBondContact OH-NE2 3.5Å; L186-H190 CarbonylContact O-C 3.59Å; L186-H190 PolarHBondContact O-N 3.18Å; H190-L192 PolarHBondContact O-N 2.78Å; H190-R193 HydrophobicContact CB-CB 4.04Å; H190-R193 HydrophobicContact CB-CG 4.41Å; H190-R193 CarbonylContact O-C 3.55Å; H190-R193 PolarHBondContact O-N 3.43Å; H190-A194 WeakPolarHBondContact O-CB 3.38Å; H190-A194 PolarHBondContact O-N 2.88Å
191	P	81.8	Confident	85	Confident	77 Å²	77	75.6 Å²	75.6	50%	0.5	36%	0.361	S	S	.	.	H	α-helix	trans	-56.5	-29.8	-168.4	22.4	-34.9	0	0	0	115.1	V189 A194 R195	V189-P191 VanDerWaalsContact C-CD 3.43Å; P191-A194 WeakPolarHBondContact O-CB 3.4Å; P191-R195 PolarHBondContact O-N 3.33Å
192	L	82.9	Confident	85	Confident	146 Å²	146	78.2 Å²	78.2	76%	0.764	37%	0.374	S	S	*	.	H	α-helix	trans	-72.2	-45.3	174.2	-63.3	178.8	0	0	0	112.3	H190 A194 R195	H190-L192 PolarHBondContact O-N 2.78Å; L192-A194 VanDerWaalsContact C-N 3.27Å; L192-A194 PolarHBondContact O-N 3.02Å; L192-R195 PolarHBondContact O-N 3.01Å
193	R	80.4	Confident	85	Confident	158 Å²	158	75.6 Å²	75.6	60%	0.596	36%	0.36	S	S	*	.	H	α-helix	trans	-67.3	-32	173.3	-60.6	179.3	171.1	170.2	-5.4	111	H190 R195 V196 L197	H190-R193 HydrophobicContact CB-CB 4.04Å; H190-R193 HydrophobicContact CB-CG 4.41Å; H190-R193 CarbonylContact O-C 3.55Å; H190-R193 PolarHBondContact O-N 3.43Å; R193-R195 VanDerWaalsContact C-N 3.27Å; R193-R195 PolarHBondContact O-N 3.42Å; R193-V196 PolarHBondContact O-N 3.31Å; R193-L197 HydrophobicContact CB-CD1 3.95Å; R193-L197 HydrophobicContact CB-CG 4.45Å; R193-L197 WeakPolarHBondContact O-CB 3.28Å; R193-L197 WeakPolarHBondContact O-CG 3.18Å; R193-L197 PolarHBondContact O-N 2.83Å
194	A	80.1	Confident	85.1	Confident	9 Å²	9	78 Å²	78	7%	0.074	38%	0.375	C	S	.	.	H	α-helix	trans	-56.6	-39.7	178.4	0	0	0	0	0	112.2	L186 H190 P191 L192 V196 R198	L186-A194 WeakPolarHBondContact O-CB 3.17Å; H190-A194 WeakPolarHBondContact O-CB 3.38Å; H190-A194 PolarHBondContact O-N 2.88Å; P191-A194 WeakPolarHBondContact O-CB 3.4Å; L192-A194 VanDerWaalsContact C-N 3.27Å; L192-A194 PolarHBondContact O-N 3.02Å; A194-V196 PolarHBondContact O-N 2.91Å; A194-R198 HydrophobicContact CB-CG 4.26Å; A194-R198 WeakPolarHBondContact O-CB 3.32Å; A194-R198 WeakPolarHBondContact O-CG 3.34Å; A194-R198 PolarHBondContact O-N 3.09Å
195	R	78	Confident	85.5	Confident	226 Å²	226	76.9 Å²	76.9	85%	0.853	38%	0.38	S	S	*	.	H	α-helix	trans	-61.6	-26.6	175.7	-70.6	-175.3	176.7	-164.9	-1	113.7	P191 L192 R193	P191-R195 PolarHBondContact O-N 3.33Å; L192-R195 PolarHBondContact O-N 3.01Å; R193-R195 VanDerWaalsContact C-N 3.27Å; R193-R195 PolarHBondContact O-N 3.42Å
196	V	80.3	Confident	85.8	Confident	120 Å²	120	76.4 Å²	76.4	73%	0.727	38%	0.381	S	S	*	.	H	α-helix	trans	-98.3	-42.1	-178.3	-175.2	0	0	0	0	111.5	R193 A194	R193-V196 PolarHBondContact O-N 3.31Å; A194-V196 PolarHBondContact O-N 2.91Å
197	L	79.5	Confident	86.1	Confident	84 Å²	84	75.8 Å²	75.8	44%	0.44	38%	0.378	S	S	.	.	H	α-helix	trans	-85.1	-34.3	-173.2	-64.9	178.3	0	0	0	113.6	L186 R193 G199 L202	L186-L197 HydrophobicContact CD2-CD1 4.38Å; R193-L197 HydrophobicContact CB-CD1 3.95Å; R193-L197 HydrophobicContact CB-CG 4.45Å; R193-L197 WeakPolarHBondContact O-CB 3.28Å; R193-L197 WeakPolarHBondContact O-CG 3.18Å; R193-L197 PolarHBondContact O-N 2.83Å; L197-G199 PolarHBondContact O-N 2.85Å; L197-L202 HydrophobicContact CB-CD2 4.48Å; L197-L202 VanDerWaalsContact O-CB 3.3Å; L197-L202 WeakPolarHBondContact O-CB 3.28Å; L197-L202 WeakPolarHBondContact O-CD2 3.4Å
198	R	83.8	Confident	86.7	Confident	66 Å²	66	79.2 Å²	79.2	25%	0.249	39%	0.393	C	S	.	.	S	Bend	trans	-80.2	53.7	180	-57.2	174.8	68.5	-140.3	-3.4	110.9	P120 S121 D183 R184 L186 A194	P120-R198 HydrophobicContact CG-CB 4.36Å; P120-R198 WeakPolarHBondContact CG-O 3.34Å; S121-R198 PolarHBondContact OG-NH2 2.81Å; D183-R198 VanDerWaalsContact CG-NH2 3.26Å; D183-R198 IonicContact OD1-CZ 3.6Å; D183-R198 IonicContact OD1-NE 2.85Å; D183-R198 PolarHBondContact OD1-NE 3.35Å; D183-R198 IonicContact OD1-NH2 3.21Å; D183-R198 PolarHBondContact OD1-NH2 3.41Å; D183-R198 IonicContact OD2-CZ 3.15Å; D183-R198 IonicContact OD2-NE 2.69Å; D183-R198 IonicContact OD2-NH2 2.67Å; D183-R198 PolarHBondContact OD2-NH2 2.81Å; R184-R198 VanDerWaalsContact NH2-NH2 3.13Å; L186-R198 HydrophobicContact CB-CG 4.25Å; A194-R198 HydrophobicContact CB-CG 4.26Å; A194-R198 WeakPolarHBondContact O-CB 3.32Å; A194-R198 WeakPolarHBondContact O-CG 3.34Å; A194-R198 PolarHBondContact O-N 3.09Å
199	G	85.3	Confident	87.3	Confident	30 Å²	30	81.8 Å²	81.8	31%	0.309	41%	0.409	S	S	.	.	S	Bend	trans	-93.8	162.5	170.3	0	0	0	0	0	111.5	L197 R201 L202 T203	L197-G199 PolarHBondContact O-N 2.85Å; G199-R201 PolarHBondContact O-N 3.35Å; G199-R201 VanDerWaalsContact O-N 3.08Å; G199-L202 PolarHBondContact O-N 3.28Å; G199-L202 VanDerWaalsContact O-N 3.12Å; G199-T203 PolarHBondContact O-N 3.11Å; G199-T203 PolarHBondContact O-OG1 3.16Å
200	Q	85.1	Confident	87.8	Confident	90 Å²	90	80.3 Å²	80.3	42%	0.421	40%	0.401	S	S	.	.	H	α-helix	trans	-51.6	-34.5	177	-171.2	64.4	21.3	0	0	112.9	T203 T204	Q200-T203 PolarHBondContact O-N 2.94Å; Q200-T204 PolarHBondContact NE2-OG1 2.79Å; Q200-T204 WeakPolarHBondContact O-CB 3.24Å; Q200-T204 PolarHBondContact O-N 3.07Å; Q200-T204 PolarHBondContact O-OG1 3.02Å
201	R	88.1	Confident	88.4	Confident	237 Å²	237	81.8 Å²	81.8	89%	0.894	41%	0.405	S	S	*	.	H	α-helix	trans	-60.8	-47	179	-65.8	-177.2	-178.5	175.3	0.2	113	G199 T203 G205	G199-R201 PolarHBondContact O-N 3.35Å; G199-R201 VanDerWaalsContact O-N 3.08Å; R201-T203 VanDerWaalsContact C-N 3.35Å; R201-G205 PolarHBondContact O-N 2.93Å
202	L	90.6	Very high	89.2	Confident	65 Å²	65	83.9 Å²	83.9	34%	0.34	41%	0.411	S	S	.	.	H	α-helix	trans	-63.5	-45.6	177.1	175.7	62.4	0	0	0	109.9	L186 L197 G199 G205 L206	L186-L202 HydrophobicContact CD1-CD2 4.01Å; L197-L202 HydrophobicContact CB-CD2 4.48Å; L197-L202 VanDerWaalsContact O-CB 3.3Å; L197-L202 WeakPolarHBondContact O-CB 3.28Å; L197-L202 WeakPolarHBondContact O-CD2 3.4Å; G199-L202 PolarHBondContact O-N 3.28Å; G199-L202 VanDerWaalsContact O-N 3.12Å; L202-G205 PolarHBondContact O-N 3.42Å; L202-L206 HydrophobicContact CD1-CD1 4.22Å; L202-L206 HydrophobicContact CD1-CG 4.17Å; L202-L206 HydrophobicContact CG-CD1 4.03Å; L202-L206 HydrophobicContact CG-CG 4.4Å; L202-L206 WeakPolarHBondContact O-CG 3.48Å; L202-L206 PolarHBondContact O-N 3.47Å
203	T	92	Very high	89.9	Confident	3 Å²	3	79 Å²	79	2%	0.018	39%	0.389	C	S	.	.	H	α-helix	trans	-60.1	-52.2	-179.6	-51.2	0	0	0	0	112.6	P120 V123 L124 G199 Q200 R201 G205 L206 C207	P120-T203 WeakPolarHBondContact CA-OG1 3.01Å; P120-T203 HydrophobicContact CB-CG2 4.47Å; P120-T203 VanDerWaalsContact CB-OG1 3.28Å; P120-T203 WeakPolarHBondContact CB-OG1 3.46Å; P120-T203 WeakPolarHBondContact O-CG2 3.44Å; V123-T203 HydrophobicContact CB-CG2 3.82Å; V123-T203 HydrophobicContact CG1-CG2 3.85Å; L124-T203 HydrophobicContact CD2-CG2 4.48Å; L124-T203 HydrophobicContact CG-CG2 3.98Å; G199-T203 PolarHBondContact O-N 3.11Å; G199-T203 PolarHBondContact O-OG1 3.16Å; Q200-T203 PolarHBondContact O-N 2.94Å; R201-T203 VanDerWaalsContact C-N 3.35Å; T203-G205 VanDerWaalsContact C-N 3.27Å; T203-G205 PolarHBondContact O-N 3.49Å; T203-L206 PolarHBondContact O-N 2.89Å; T203-C207 PolarHBondContact O-N 3.01Å; T203-C207 PolarHBondContact O-SG 2.64Å; T203-C207 VanDerWaalsContact O-SG 3.36Å
204	T	91.9	Very high	90.7	Very high	58 Å²	58	71.7 Å²	71.7	36%	0.356	36%	0.363	S	S	.	.	H	α-helix	trans	-60.5	-39.5	175.9	-63.6	0	0	0	0	110.8	Q200 C207 L208	Q200-T204 PolarHBondContact NE2-OG1 2.79Å; Q200-T204 WeakPolarHBondContact O-CB 3.24Å; Q200-T204 PolarHBondContact O-N 3.07Å; Q200-T204 PolarHBondContact O-OG1 3.02Å; T204-C207 PolarHBondContact O-N 3.38Å; T204-L208 HydrophobicContact CG2-CD1 3.87Å; T204-L208 HydrophobicContact CG2-CG 4.3Å; T204-L208 WeakPolarHBondContact O-CB 3.45Å; T204-L208 VanDerWaalsContact O-CG 3.25Å; T204-L208 WeakPolarHBondContact O-CG 3.46Å; T204-L208 PolarHBondContact O-N 3.39Å
205	G	95.4	Very high	91.5	Very high	29 Å²	29	74.2 Å²	74.2	30%	0.299	38%	0.383	S	S	.	.	H	α-helix	trans	-59.7	-46.3	173.4	0	0	0	0	0	113.1	R201 L202 T203 L208 V209	R201-G205 PolarHBondContact O-N 2.93Å; L202-G205 PolarHBondContact O-N 3.42Å; T203-G205 VanDerWaalsContact C-N 3.27Å; T203-G205 PolarHBondContact O-N 3.49Å; G205-L208 PolarHBondContact O-N 2.99Å; G205-V209 WeakPolarHBondContact O-CB 3.46Å; G205-V209 VanDerWaalsContact O-CG2 3.29Å; G205-V209 WeakPolarHBondContact O-CG2 3Å; G205-V209 PolarHBondContact O-N 3.47Å
206	L	95.8	Very high	92.3	Very high	41 Å²	41	66.4 Å²	66.4	22%	0.215	37%	0.367	C	S	.	.	H	α-helix	trans	-62.9	-43.9	176.9	-71.1	171.1	0	0	0	112	L124 A179 L182 L202 T203 V209 A210	L124-L206 HydrophobicContact CD2-CB 4.49Å; A179-L206 HydrophobicContact CB-CB 4.04Å; A179-L206 HydrophobicContact CB-CD1 4.26Å; L182-L206 HydrophobicContact CD2-CD1 4.34Å; L182-L206 HydrophobicContact CD2-CD2 4.17Å; L202-L206 HydrophobicContact CD1-CD1 4.22Å; L202-L206 HydrophobicContact CD1-CG 4.17Å; L202-L206 HydrophobicContact CG-CD1 4.03Å; L202-L206 HydrophobicContact CG-CG 4.4Å; L202-L206 WeakPolarHBondContact O-CG 3.48Å; L202-L206 PolarHBondContact O-N 3.47Å; T203-L206 PolarHBondContact O-N 2.89Å; L206-V209 PolarHBondContact O-N 3.24Å; L206-A210 WeakPolarHBondContact O-CB 3.22Å; L206-A210 PolarHBondContact O-N 3.48Å
207	C	96.8	Very high	93	Very high	6 Å²	6	61.5 Å²	61.5	4%	0.041	34%	0.337	C	S	.	.	H	α-helix	trans	-62.1	-46.8	175	-63.2	0	0	0	0	111.6	N127 T203 T204 V209 A210 W211	N127-C207 VanDerWaalsContact CG-SG 3.58Å; N127-C207 PolarHBondContact ND2-SG 3Å; N127-C207 VanDerWaalsContact ND2-SG 3.41Å; T203-C207 PolarHBondContact O-N 3.01Å; T203-C207 PolarHBondContact O-SG 2.64Å; T203-C207 VanDerWaalsContact O-SG 3.36Å; T204-C207 PolarHBondContact O-N 3.38Å; C207-V209 PolarHBondContact O-N 3.03Å; C207-A210 PolarHBondContact O-N 3.5Å; C207-W211 PolarHBondContact O-N 3.22Å
208	L	97.4	Very high	93.7	Very high	98 Å²	98	58 Å²	58	51%	0.513	32%	0.32	S	S	.	.	H	α-helix	trans	-61.4	-43.8	178.5	-73.9	170.6	0	0	0	111.7	T204 G205 W211 L212	T204-L208 HydrophobicContact CG2-CD1 3.87Å; T204-L208 HydrophobicContact CG2-CG 4.3Å; T204-L208 WeakPolarHBondContact O-CB 3.45Å; T204-L208 VanDerWaalsContact O-CG 3.25Å; T204-L208 WeakPolarHBondContact O-CG 3.46Å; T204-L208 PolarHBondContact O-N 3.39Å; G205-L208 PolarHBondContact O-N 2.99Å; L208-W211 PolarHBondContact O-N 2.85Å; L208-L212 VanDerWaalsContact O-CB 3.29Å; L208-L212 WeakPolarHBondContact O-CB 3.2Å; L208-L212 WeakPolarHBondContact O-CG 3.49Å; L208-L212 PolarHBondContact O-N 2.93Å
209	V	97.1	Very high	94.2	Very high	90 Å²	90	59.5 Å²	59.5	55%	0.545	33%	0.332	S	S	.	.	H	α-helix	trans	-61	-45.7	174.5	169.1	0	0	0	0	110.6	G205 L206 C207 W211 L212 S213	G205-V209 WeakPolarHBondContact O-CB 3.46Å; G205-V209 VanDerWaalsContact O-CG2 3.29Å; G205-V209 WeakPolarHBondContact O-CG2 3Å; G205-V209 PolarHBondContact O-N 3.47Å; L206-V209 PolarHBondContact O-N 3.24Å; C207-V209 PolarHBondContact O-N 3.03Å; V209-W211 PolarHBondContact O-N 3.12Å; V209-L212 PolarHBondContact O-N 3.21Å; V209-S213 WeakPolarHBondContact O-CB 3.35Å; V209-S213 PolarHBondContact O-N 3.38Å; V209-S213 PolarHBondContact O-OG 3.19Å
210	A	97.4	Very high	94.6	Very high	5 Å²	5	59.4 Å²	59.4	4%	0.041	33%	0.326	C	S	.	.	H	α-helix	trans	-59.7	-48.4	178.1	0	0	0	0	0	112.3	L175 L176 L206 C207 A214	L175-A210 HydrophobicContact CB-CB 3.84Å; L176-A210 HydrophobicContact CD2-CB 3.9Å; L176-A210 HydrophobicContact CG-CB 4.05Å; L206-A210 WeakPolarHBondContact O-CB 3.22Å; L206-A210 PolarHBondContact O-N 3.48Å; C207-A210 PolarHBondContact O-N 3.5Å; A210-A214 VanDerWaalsContact O-CB 3.26Å; A210-A214 WeakPolarHBondContact O-CB 3.28Å; A210-A214 PolarHBondContact O-N 3.36Å
211	W	97.9	Very high	95	Very high	79 Å²	79	55.1 Å²	55.1	30%	0.299	31%	0.306	S	S	.	.	H	α-helix	trans	-64.5	-45.7	178.2	-76.2	113.4	0	0	0	113	N127 V130 L134 C207 L208 V209 A214 A215	N127-W211 PolarHBondContact OD1-NE1 3.04Å; V130-W211 HydrophobicContact CG1-CH2 4.24Å; V130-W211 HydrophobicContact CG1-CZ2 4.04Å; L134-W211 HydrophobicContact CD1-CH2 3.76Å; L134-W211 HydrophobicContact CD1-CZ3 3.95Å; C207-W211 PolarHBondContact O-N 3.22Å; L208-W211 PolarHBondContact O-N 2.85Å; V209-W211 PolarHBondContact O-N 3.12Å; W211-A214 PolarHBondContact O-N 3.01Å; W211-A215 WeakPolarHBondContact O-CB 3.47Å; W211-A215 PolarHBondContact O-N 2.95Å
212	L	97.9	Very high	95.3	Very high	122 Å²	122	45.9 Å²	45.9	64%	0.639	28%	0.276	S	S	*	.	H	α-helix	trans	-67.3	-39.4	179.5	-69	173.6	0	0	0	111.7	L208 V209 A216	L208-L212 VanDerWaalsContact O-CB 3.29Å; L208-L212 WeakPolarHBondContact O-CB 3.2Å; L208-L212 WeakPolarHBondContact O-CG 3.49Å; L208-L212 PolarHBondContact O-N 2.93Å; V209-L212 PolarHBondContact O-N 3.21Å; L212-A216 VanDerWaalsContact O-CB 3.26Å; L212-A216 WeakPolarHBondContact O-CB 3.45Å; L212-A216 PolarHBondContact O-N 3.05Å
213	S	97.3	Very high	95.4	Very high	44 Å²	44	47.6 Å²	47.6	31%	0.308	29%	0.285	S	S	.	.	H	α-helix	trans	-66.7	-42.9	174.1	-67.8	0	0	0	0	111.9	V209 A215 A216 L217	V209-S213 WeakPolarHBondContact O-CB 3.35Å; V209-S213 PolarHBondContact O-N 3.38Å; V209-S213 PolarHBondContact O-OG 3.19Å; S213-A215 PolarHBondContact O-N 2.97Å; S213-A216 PolarHBondContact O-N 3.28Å; S213-L217 WeakPolarHBondContact O-CB 3.14Å; S213-L217 VanDerWaalsContact O-CG 3.24Å; S213-L217 WeakPolarHBondContact O-CG 2.96Å; S213-L217 PolarHBondContact O-N 3.15Å
214	A	96.6	Very high	95.3	Very high	4 Å²	4	50.3 Å²	50.3	3%	0.033	30%	0.298	C	S	.	.	H	α-helix	trans	-61.9	-42.8	175.5	0	0	0	0	0	112	A210 W211 L217 A218	A210-A214 VanDerWaalsContact O-CB 3.26Å; A210-A214 WeakPolarHBondContact O-CB 3.28Å; A210-A214 PolarHBondContact O-N 3.36Å; W211-A214 PolarHBondContact O-N 3.01Å; A214-L217 PolarHBondContact O-N 3.48Å; A214-A218 VanDerWaalsContact O-CB 3.3Å; A214-A218 WeakPolarHBondContact O-CB 3.36Å; A214-A218 PolarHBondContact O-N 2.95Å
215	A	96.4	Very high	95.3	Very high	61 Å²	61	51.6 Å²	51.6	50%	0.504	30%	0.296	S	S	.	.	H	α-helix	trans	-64.7	-43.1	175	0	0	0	0	0	112.3	W211 S213 A218 L219	W211-A215 WeakPolarHBondContact O-CB 3.47Å; W211-A215 PolarHBondContact O-N 2.95Å; S213-A215 PolarHBondContact O-N 2.97Å; A215-A218 PolarHBondContact O-N 3.44Å; A215-L219 PolarHBondContact O-N 3.09Å
216	A	96.6	Very high	95.3	Very high	62 Å²	62	50.2 Å²	50.2	51%	0.512	28%	0.282	S	S	.	.	H	α-helix	trans	-65.7	-37.2	177.2	0	0	0	0	0	112.7	L212 S213 P220	L212-A216 VanDerWaalsContact O-CB 3.26Å; L212-A216 WeakPolarHBondContact O-CB 3.45Å; L212-A216 PolarHBondContact O-N 3.05Å; S213-A216 PolarHBondContact O-N 3.28Å; A216-P220 WeakPolarHBondContact O-CD 3.47Å
217	L	94.6	Very high	95.2	Very high	18 Å²	18	48.5 Å²	48.5	9%	0.094	27%	0.273	C	S	.	.	H	α-helix	trans	-72.1	-31.3	173.2	-68.8	172.5	0	0	0	112.2	Y171 S213 A214 P220 L258 L261	Y171-L217 HydrophobicContact CG-CD1 4.47Å; S213-L217 WeakPolarHBondContact O-CB 3.14Å; S213-L217 VanDerWaalsContact O-CG 3.24Å; S213-L217 WeakPolarHBondContact O-CG 2.96Å; S213-L217 PolarHBondContact O-N 3.15Å; A214-L217 PolarHBondContact O-N 3.48Å; L217-P220 WeakPolarHBondContact O-CD 3.36Å; L217-L258 HydrophobicContact CD2-CD1 4.49Å; L217-L258 VanDerWaalsContact O-CD1 3.26Å; L217-L258 WeakPolarHBondContact O-CD1 3.4Å; L217-L261 HydrophobicContact CD2-CB 4.07Å; L217-L261 HydrophobicContact CD2-CD1 4.34Å
218	A	94.6	Very high	95	Very high	11 Å²	11	48.5 Å²	48.5	9%	0.091	27%	0.272	C	S	.	.	H	α-helix	trans	-75.7	-24.5	175.1	0	0	0	0	0	113.2	A164 A214 A215 L221	A164-A218 HydrophobicContact CB-CB 4.25Å; A164-A218 WeakPolarHBondContact O-CB 3.17Å; A214-A218 VanDerWaalsContact O-CB 3.3Å; A214-A218 WeakPolarHBondContact O-CB 3.36Å; A214-A218 PolarHBondContact O-N 2.95Å; A215-A218 PolarHBondContact O-N 3.44Å; A218-L221 VanDerWaalsContact O-CB 3.27Å; A218-L221 WeakPolarHBondContact O-CB 3.5Å; A218-L221 PolarHBondContact O-N 3.03Å; A218-L221 VanDerWaalsContact O-N 3.09Å
219	L	94.6	Very high	94.8	Very high	97 Å²	97	50.2 Å²	50.2	51%	0.508	27%	0.272	S	S	.	.	H	α-helix	trans	-56.4	-44.6	-173.4	-178.2	65.6	0	0	0	114.9	A215 L221 T222	A215-L219 PolarHBondContact O-N 3.09Å; L219-L221 PolarHBondContact O-N 2.98Å; L219-T222 PolarHBondContact O-N 3.2Å; L219-T222 PolarHBondContact O-OG1 3.13Å
220	P	92.8	Very high	94.5	Very high	27 Å²	27	46 Å²	46	18%	0.175	25%	0.247	C	C	.	.	H	α-helix	trans	-59	-22.2	178.2	-25.3	35.8	0	0	0	114	A216 L217 H250 A254	A216-P220 WeakPolarHBondContact O-CD 3.47Å; L217-P220 WeakPolarHBondContact O-CD 3.36Å; P220-H250 PolarHBondContact O-CE1 3.29Å; P220-H250 PolarHBondContact O-NE2 2.84Å; P220-A254 HydrophobicContact CB-CB 4.17Å
221	L	93.1	Very high	94.2	Very high	0 Å²	0	46.9 Å²	46.9	0%	0	25%	0.253	C	S	.	.	H	α-helix	trans	-75	-28.6	177.3	-50.1	177	0	0	0	111.4	T163 A164 Y167 A218 L219 Q226 W251 F255 L258	T163-L221 HydrophobicContact CG2-CD1 4.43Å; A164-L221 HydrophobicContact CB-CB 4.34Å; Y167-L221 HydrophobicContact CD2-CD1 3.47Å; Y167-L221 VanDerWaalsContact CD2-CD1 3.47Å; Y167-L221 HydrophobicContact CE2-CD1 4.21Å; Y167-L221 HydrophobicContact CG-CD1 3.72Å; A218-L221 VanDerWaalsContact O-CB 3.27Å; A218-L221 WeakPolarHBondContact O-CB 3.5Å; A218-L221 PolarHBondContact O-N 3.03Å; A218-L221 VanDerWaalsContact O-N 3.09Å; L219-L221 PolarHBondContact O-N 2.98Å; L221-Q226 PolarHBondContact O-NE2 3.47Å; L221-W251 HydrophobicContact CD2-CE3 4.49Å; L221-W251 HydrophobicContact CD2-CZ3 3.85Å; L221-F255 HydrophobicContact CD2-CE1 3.71Å; L221-F255 HydrophobicContact CD2-CZ 3.86Å; L221-L258 HydrophobicContact CD1-CD2 4.09Å; L221-L258 HydrophobicContact CD2-CD2 4.09Å; L221-L258 HydrophobicContact CG-CD2 4.31Å
222	T	94.4	Very high	93.6	Very high	43 Å²	43	47.4 Å²	47.4	26%	0.264	28%	0.284	S	S	.	.	H	α-helix	trans	-82.4	-12.6	-179.8	63.2	0	0	0	0	114.1	R160 A164 L219	R160-T222 WeakPolarHBondContact CD-O 3.43Å; R160-T222 PolarHBondContact NH1-O 3.09Å; R160-T222 VanDerWaalsContact NH1-O 3.08Å; A164-T222 HydrophobicContact CB-CG2 3.52Å; L219-T222 PolarHBondContact O-N 3.2Å; L219-T222 PolarHBondContact O-OG1 3.13Å
223	L	92.3	Very high	93.2	Very high	102 Å²	102	43.7 Å²	43.7	53%	0.534	27%	0.268	S	S	.	.	H	α-helix	trans	-79	-42.2	-175.4	-57.3	-179.1	0	0	0	112.6	R160	R160-L223 PolarHBondContact NH1-O 2.81Å
224	Q	90.6	Very high	92.8	Very high	60 Å²	60	49 Å²	49	28%	0.28	29%	0.293	S	S	.	.	S	Bend	trans	-90.4	158	-174.5	-70.4	-61.7	-9.1	0	0	114.1	R160 H250 W251	R160-Q224 WeakPolarHBondContact CD-O 3.27Å; R160-Q224 VanDerWaalsContact CZ-O 3.22Å; R160-Q224 PolarHBondContact NE-O 3.47Å; R160-Q224 VanDerWaalsContact NE-O 3.07Å; Q224-H250 HydrophobicContact CG-CB 4.45Å; Q224-H250 VanDerWaalsContact CG-CD2 3.43Å; Q224-H250 WeakPolarHBondContact CG-CD2 3.48Å; Q224-H250 VanDerWaalsContact CG-CE1 3.5Å; Q224-H250 WeakPolarHBondContact CG-CE1 3.21Å; Q224-H250 WeakPolarHBondContact CG-NE2 3.46Å; Q224-W251 HydrophobicContact CB-CH2 3.94Å; Q224-W251 HydrophobicContact CB-CZ2 3.56Å; Q224-W251 HydrophobicContact CG-CZ2 4.3Å
225	R	92.9	Very high	92.6	Very high	84 Å²	84	50.6 Å²	50.6	32%	0.317	30%	0.3	S	S	.	.			trans	-68.8	136.8	173.5	-175.5	178.4	173.1	166.2	2.7	111.6	D69 E156 T227 F228	D69-R225 IonicContact OD1-CZ 3.61Å; D69-R225 IonicContact OD1-NH1 3.82Å; D69-R225 PolarHBondContact OD1-NH1 2.97Å; D69-R225 IonicContact OD1-NH2 3.82Å; D69-R225 PolarHBondContact OD1-NH2 3.49Å; E156-R225 WeakPolarHBondContact OE1-CA 3.43Å; E156-R225 WeakPolarHBondContact OE1-CG 3.32Å; R225-T227 PolarHBondContact NE-O 3.18Å; R225-T227 PolarHBondContact NH2-O 2.86Å; R225-F228 HydrophobicContact CB-CZ 4.02Å; R225-F228 HydrophobicContact CG-CE1 4.12Å; R225-F228 HydrophobicContact CG-CE2 4.16Å; R225-F228 HydrophobicContact CG-CZ 3.67Å
226	Q	93.6	Very high	92.5	Very high	0 Å²	0	50.2 Å²	50.2	0%	0	29%	0.288	C	S	.	.			trans	-128.2	-12.8	-177.5	-63.6	-166.9	23.4	0	0	115.7	E156 R160 T163 L221 H239 L242 W251	E156-Q226 PolarHBondContact OE1-N 3.49Å; E156-Q226 PolarHBondContact OE2-N 2.98Å; R160-Q226 HydrophobicContact CG-CB 4.49Å; R160-Q226 HydrophobicContact CG-CG 4.27Å; T163-Q226 PolarHBondContact OG1-OE1 3.4Å; L221-Q226 PolarHBondContact O-NE2 3.47Å; Q226-H239 PolarHBondContact O-N 2.91Å; Q226-H239 PolarHBondContact OE1-ND1 2.82Å; Q226-H239 VanDerWaalsContact OE1-ND1 3.15Å; Q226-L242 HydrophobicContact CG-CD2 4.48Å; Q226-W251 HydrophobicContact CG-CH2 4Å; Q226-W251 HydrophobicContact CG-CZ2 4.4Å
227	T	95	Very high	92.3	Very high	6 Å²	6	47.3 Å²	47.3	4%	0.037	26%	0.264	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-102	131.3	173.2	59.2	0	0	0	0	112.9	E156 C159 R225 L237 C238	E156-T227 VanDerWaalsContact OE2-CB 3.23Å; E156-T227 WeakPolarHBondContact OE2-CB 3.45Å; E156-T227 VanDerWaalsContact OE2-CG2 3.31Å; E156-T227 WeakPolarHBondContact OE2-CG2 3.38Å; E156-T227 PolarHBondContact OE2-N 3.48Å; E156-T227 PolarHBondContact OE2-OG1 3.41Å; C159-T227 HydrophobicContact CB-CG2 3.51Å; R225-T227 PolarHBondContact NE-O 3.18Å; R225-T227 PolarHBondContact NH2-O 2.86Å; T227-L237 VanDerWaalsContact CA-O 3.27Å; T227-L237 WeakPolarHBondContact CA-O 3.28Å; T227-C238 HydrophobicContact CG2-CB 4.37Å
228	F	92.5	Very high	92.3	Very high	6 Å²	6	46.4 Å²	46.4	3%	0.026	26%	0.259	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-144.9	148.9	179.4	-61.3	-82.2	0	0	0	109.2	F63 D69 L71 R225 L237 L242 P243	F63-F228 HydrophobicContact CE1-CD1 4.19Å; F63-F228 AromaticContact CE1-CE1 3.83Å; F63-F228 HydrophobicContact CE1-CE1 3.83Å; F63-F228 HydrophobicContact CZ-CE1 4.3Å; D69-F228 CarbonylContact O-C 3.59Å; D69-F228 WeakPolarHBondContact O-CA 3.47Å; L71-F228 HydrophobicContact CB-CB 4.47Å; L71-F228 HydrophobicContact CD1-CB 3.58Å; L71-F228 HydrophobicContact CD1-CD1 4.03Å; L71-F228 HydrophobicContact CD1-CD2 3.71Å; L71-F228 HydrophobicContact CD1-CE2 4.44Å; L71-F228 HydrophobicContact CD1-CG 3.48Å; L71-F228 VanDerWaalsContact CD1-CG 3.48Å; L71-F228 HydrophobicContact CD2-CD1 4.48Å; L71-F228 HydrophobicContact CG-CB 3.74Å; L71-F228 HydrophobicContact CG-CD1 4.01Å; L71-F228 HydrophobicContact CG-CG 3.84Å; R225-F228 HydrophobicContact CB-CZ 4.02Å; R225-F228 HydrophobicContact CG-CE1 4.12Å; R225-F228 HydrophobicContact CG-CE2 4.16Å; R225-F228 HydrophobicContact CG-CZ 3.67Å; F228-L237 PolarHBondContact N-O 3.01Å; F228-L237 PolarHBondContact O-N 3.27Å; F228-L242 HydrophobicContact CE2-CD2 4.4Å; F228-P243 HydrophobicContact CE1-CG 3.94Å; F228-P243 HydrophobicContact CE2-CG 3.99Å; F228-P243 HydrophobicContact CZ-CG 3.47Å; F228-P243 VanDerWaalsContact CZ-CG 3.47Å
229	R	93.6	Very high	92.1	Very high	133 Å²	133	46.4 Å²	46.4	50%	0.502	26%	0.257	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-78.8	144.7	172.2	-68	178.8	173.8	176	-2.4	110.1	D69 T70 L71 Q235 M236	D69-R229 PolarHBondContact O-N 3.35Å; T70-R229 WeakPolarHBondContact CA-O 3.4Å; T70-R229 HydrophobicContact CG2-CB 4.28Å; L71-R229 PolarHBondContact N-O 2.88Å; R229-Q235 WeakPolarHBondContact CA-O 3.28Å; R229-M236 HydrophobicContact CG-CE 4.21Å
230	L	90.6	Very high	91.5	Very high	3 Å²	3	42.7 Å²	42.7	2%	0.016	24%	0.238	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-81.3	126.7	170.9	179.4	57.6	0	0	0	110.1	L73 Q78 L81 G232 S233 Q235 L237	L73-L230 HydrophobicContact CB-CD1 4.21Å; L73-L230 HydrophobicContact CD1-CD1 3.45Å; L73-L230 VanDerWaalsContact CD1-CD1 3.45Å; L73-L230 HydrophobicContact CG-CD1 3.85Å; Q78-L230 HydrophobicContact CG-CD1 4.27Å; L81-L230 HydrophobicContact CD2-CD2 4.22Å; L230-G232 PolarHBondContact O-N 3.5Å; L230-S233 PolarHBondContact O-N 2.81Å; L230-S233 VanDerWaalsContact O-N 3.13Å; L230-Q235 HydrophobicContact CB-CB 4.32Å; L230-Q235 PolarHBondContact N-O 3.2Å; L230-L237 HydrophobicContact CB-CD1 4.28Å; L230-L237 HydrophobicContact CB-CG 4.38Å
231	A	90	Very high	91	Very high	22 Å²	22	41.5 Å²	41.5	18%	0.182	23%	0.23	C	C	.	.	T	Hydrogen-bonded Turn	trans	-58.1	123.8	175.3	0	0	0	0	0	111.2	T70 L71 E72	T70-A231 HydrophobicContact CG2-CB 3.9Å; L71-A231 WeakPolarHBondContact O-CB 3.18Å; L71-A231 PolarHBondContact O-N 3.5Å; E72-A231 HydrophobicContact CB-CB 4.37Å; E72-A231 HydrophobicContact CG-CB 3.78Å
232	G	86.6	Confident	90.6	Very high	91 Å²	91	41.9 Å²	41.9	94%	0.938	23%	0.232	S	C	*	.	T	Hydrogen-bonded Turn	trans	88.1	6.3	-178.9	0	0	0	0	0	115.7	L230	L230-G232 PolarHBondContact O-N 3.5Å
233	S	88.3	Confident	90	Very high	43 Å²	43	40.3 Å²	40.3	30%	0.301	22%	0.223	S	C	.	.	S	Bend	trans	-147.4	165	170.2	80.7	0	0	0	0	113.2	L230 Q235	L230-S233 PolarHBondContact O-N 2.81Å; L230-S233 VanDerWaalsContact O-N 3.13Å; S233-Q235 PolarHBondContact O-N 3.17Å; S233-Q235 WeakPolarHBondContact OG-CB 3.35Å; S233-Q235 PolarHBondContact OG-N 2.95Å; S233-Q235 PolarHBondContact OG-OE1 3.46Å
234	D	88.7	Confident	89.3	Confident	156 Å²	156	39 Å²	39	83%	0.834	22%	0.216	S	C	*	.	S	Bend	trans	-82	17.5	173.8	-67	-45.4	0	0	0	113	H151 M236	H151-D234 PolarHBondContact CE1-O 3.34Å; H151-D234 VanDerWaalsContact CE1-O 3.28Å; H151-D234 PolarHBondContact ND1-O 2.85Å; D234-M236 PolarHBondContact O-N 3.38Å
235	Q	92.2	Very high	88.6	Confident	38 Å²	38	39.4 Å²	39.4	18%	0.178	23%	0.229	C	C	.	.			trans	-79.4	119	-179.3	-71.1	159.8	-48.6	0	0	110.9	G149 R229 L230 S233 L237	G149-Q235 PolarHBondContact O-NE2 3.18Å; R229-Q235 WeakPolarHBondContact CA-O 3.28Å; L230-Q235 HydrophobicContact CB-CB 4.32Å; L230-Q235 PolarHBondContact N-O 3.2Å; S233-Q235 PolarHBondContact O-N 3.17Å; S233-Q235 WeakPolarHBondContact OG-CB 3.35Å; S233-Q235 PolarHBondContact OG-N 2.95Å; S233-Q235 PolarHBondContact OG-OE1 3.46Å; Q235-L237 HydrophobicContact CB-CD2 4.23Å
236	M	94.7	Very high	88.1	Confident	52 Å²	52	38.7 Å²	38.7	26%	0.256	23%	0.23	S	C	.	.	E	Extended strand (participates in β ladder)	trans	-90	105.5	167.9	-174.9	159.8	-72.4	0	0	108.9	H151 W152 R229 D234	H151-M236 CarbonylContact C-O 3.55Å; H151-M236 PolarHBondContact ND1-N 2.86Å; W152-M236 VanDerWaalsContact CB-O 3.31Å; W152-M236 WeakPolarHBondContact CB-O 3.39Å; W152-M236 PolarHBondContact N-O 2.84Å; R229-M236 HydrophobicContact CG-CE 4.21Å; D234-M236 PolarHBondContact O-N 3.38Å
237	L	92.6	Very high	87.5	Confident	1 Å²	1	40.3 Å²	40.3	1%	0.005	24%	0.237	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-75.1	151.9	180	-52.8	-175.5	0	0	0	110.2	L73 L81 Q150 T227 F228 L230 Q235 A241	L73-L237 HydrophobicContact CD1-CD1 3.91Å; L81-L237 HydrophobicContact CD2-CD1 3.8Å; L81-L237 HydrophobicContact CD2-CD2 3.74Å; L81-L237 HydrophobicContact CD2-CG 4.45Å; Q150-L237 HydrophobicContact CB-CD2 4.17Å; Q150-L237 WeakPolarHBondContact O-CD2 3.27Å; T227-L237 VanDerWaalsContact CA-O 3.27Å; T227-L237 WeakPolarHBondContact CA-O 3.28Å; F228-L237 PolarHBondContact N-O 3.01Å; F228-L237 PolarHBondContact O-N 3.27Å; L230-L237 HydrophobicContact CB-CD1 4.28Å; L230-L237 HydrophobicContact CB-CG 4.38Å; Q235-L237 HydrophobicContact CB-CD2 4.23Å; L237-A241 HydrophobicContact CD1-CB 3.69Å
238	C	94.1	Very high	86.8	Confident	0 Å²	0	44.2 Å²	44.2	0%	0	26%	0.261	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-129.7	109.8	172.9	169.6	0	0	0	0	110.5	R142 Y145 W152 C159 T227 D240	R142-C238 PolarHBondContact NH1-O 3.37Å; Y145-C238 HydrophobicContact CD2-CB 4.49Å; Y145-C238 HydrophobicContact CE2-CB 4.13Å; Y145-C238 PolarHBondContact OH-N 3.25Å; W152-C238 HydrophobicContact CB-CB 3.79Å; W152-C238 HydrophobicContact CD2-CB 3.68Å; W152-C238 HydrophobicContact CE3-CB 3.75Å; W152-C238 HydrophobicContact CG-CB 3.68Å; C159-C238 VanDerWaalsContact CA-SG 3.5Å; C159-C238 HydrophobicContact CB-CB 4Å; C159-C238 WeakPolarHBondContact CB-SG 3.18Å; C159-C238 WeakPolarHBondContact SG-CA 3.16Å; C159-C238 WeakPolarHBondContact SG-CB 3.35Å; C159-C238 CovalentContact SG-SG 2.04Å; C159-C238 PolarHBondContact SG-SG 3.33Å; T227-C238 HydrophobicContact CG2-CB 4.37Å; C238-D240 PolarHBondContact O-N 3.11Å
239	H	90.9	Very high	86.5	Confident	10 Å²	10	47.2 Å²	47.2	5%	0.046	28%	0.283	C	S	.	.	S	Bend	trans	66.2	-19.3	178.7	-162.5	58.4	0	0	0	117	T163 Y167 Q226 A241 F255	T163-H239 HydrophobicContact CG2-CB 4.38Å; Y167-H239 AromaticContact CE2-NE2 3.66Å; Y167-H239 PolarHBondContact OH-NE2 3.35Å; Q226-H239 PolarHBondContact O-N 2.91Å; Q226-H239 PolarHBondContact OE1-ND1 2.82Å; Q226-H239 VanDerWaalsContact OE1-ND1 3.15Å; H239-A241 VanDerWaalsContact C-N 3.32Å; H239-A241 PolarHBondContact O-N 2.83Å; H239-F255 AromaticContact CE1-CZ 3.7Å; H239-F255 AromaticContact NE2-CZ 3.76Å
240	D	82.8	Confident	86.2	Confident	20 Å²	20	42.4 Å²	42.4	11%	0.107	27%	0.266	C	S	.	.	S	Bend	trans	-71.4	-25.1	-177.1	-66	-16.7	0	0	0	113.7	F59 L81 Y145 C238 Y329	F59-D240 WeakPolarHBondContact CB-O 3.12Å; F59-D240 VanDerWaalsContact CD2-O 3.3Å; F59-D240 WeakPolarHBondContact CD2-O 3.25Å; L81-D240 HydrophobicContact CD1-CB 3.82Å; Y145-D240 WeakPolarHBondContact CE1-OD2 3.4Å; Y145-D240 VanDerWaalsContact CZ-OD2 3.31Å; Y145-D240 PolarHBondContact OH-OD2 3.43Å; C238-D240 PolarHBondContact O-N 3.11Å; D240-Y329 HydrophobicContact CB-CE2 4.4Å; D240-Y329 WeakPolarHBondContact CB-OH 3.41Å
241	A	82.4	Confident	86	Confident	1 Å²	1	42.4 Å²	42.4	1%	0.008	27%	0.266	C	S	.	.	S	Bend	trans	-131.4	132.9	173.1	0	0	0	0	0	110.4	F59 L71 L73 L237 H239	F59-A241 HydrophobicContact CB-CB 3.7Å; F59-A241 HydrophobicContact CG-CB 4.3Å; L71-A241 HydrophobicContact CD1-CB 4.35Å; L73-A241 HydrophobicContact CD1-CB 3.82Å; L73-A241 HydrophobicContact CD2-CB 4.09Å; L237-A241 HydrophobicContact CD1-CB 3.69Å; H239-A241 VanDerWaalsContact C-N 3.32Å; H239-A241 PolarHBondContact O-N 2.83Å
242	L	84	Confident	86	Confident	9 Å²	9	46.5 Å²	46.5	5%	0.047	28%	0.276	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-136.2	152.6	-174.3	-66.4	168.7	0	0	0	110	F59 P60 G61 Q226 F228 L244 W251 Y317	F59-L242 PolarHBondContact O-N 3.24Å; F59-L242 VanDerWaalsContact O-N 3.1Å; F59-L242 VanDerWaalsContact O-O 3.06Å; P60-L242 CarbonylContact C-O 3.35Å; P60-L242 WeakPolarHBondContact CA-O 3.2Å; G61-L242 PolarHBondContact N-O 3.16Å; Q226-L242 HydrophobicContact CG-CD2 4.48Å; F228-L242 HydrophobicContact CE2-CD2 4.4Å; L242-L244 PolarHBondContact O-N 3.13Å; L242-W251 HydrophobicContact CD1-CD2 3.91Å; L242-W251 HydrophobicContact CD1-CE3 4.35Å; L242-W251 HydrophobicContact CD1-CG 4.3Å; L242-W251 HydrophobicContact CD1-CH2 4.41Å; L242-W251 HydrophobicContact CD1-CZ2 3.98Å; L242-W251 HydrophobicContact CD2-CH2 4.48Å; L242-W251 HydrophobicContact CD2-CZ2 3.79Å; L242-W251 HydrophobicContact CG-CZ2 4.46Å; L242-Y317 WeakPolarHBondContact CD1-OH 3.33Å
243	P	81.8	Confident	86.2	Confident	9 Å²	9	44.2 Å²	44.2	6%	0.058	25%	0.245	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-65.1	134.1	-177.1	-22.5	34.5	0	0	0	112.8	F63 F228 A245 E246	F63-P243 HydrophobicContact CE1-CG 4.17Å; F63-P243 HydrophobicContact CE2-CB 3.89Å; F63-P243 HydrophobicContact CE2-CG 4.26Å; F63-P243 HydrophobicContact CZ-CB 3.71Å; F63-P243 HydrophobicContact CZ-CG 3.55Å; F228-P243 HydrophobicContact CE1-CG 3.94Å; F228-P243 HydrophobicContact CE2-CG 3.99Å; F228-P243 HydrophobicContact CZ-CG 3.47Å; F228-P243 VanDerWaalsContact CZ-CG 3.47Å; P243-A245 PolarHBondContact O-N 3.43Å; P243-E246 PolarHBondContact O-N 3.2Å; P243-E246 VanDerWaalsContact O-N 3.15Å
244	L	77.8	Confident	86.4	Confident	75 Å²	75	42.6 Å²	42.6	39%	0.393	24%	0.235	S	C	.	.	T	Hydrogen-bonded Turn	trans	-54.6	-37.5	177.4	179.8	51.6	0	0	0	112.8	P60 G61 L242 E246 Q247	P60-L244 HydrophobicContact CB-CB 3.76Å; P60-L244 HydrophobicContact CB-CD1 3.56Å; P60-L244 HydrophobicContact CB-CG 4.12Å; P60-L244 HydrophobicContact CG-CD1 4.22Å; G61-L244 PolarHBondContact O-N 2.64Å; L242-L244 PolarHBondContact O-N 3.13Å; L244-E246 PolarHBondContact O-N 2.97Å; L244-Q247 WeakPolarHBondContact O-CB 3.46Å; L244-Q247 PolarHBondContact O-N 3.46Å; L244-Q247 VanDerWaalsContact O-N 3.13Å
245	A	76.4	Confident	86.5	Confident	68 Å²	68	35.2 Å²	35.2	56%	0.562	20%	0.195	S	C	*	.	H	α-helix	trans	-58.5	-35.3	-178.6	0	0	0	0	0	113	P243	P243-A245 PolarHBondContact O-N 3.43Å
246	E	81.4	Confident	86.5	Confident	70 Å²	70	36 Å²	36	33%	0.327	20%	0.202	S	C	.	.	H	α-helix	trans	-89.7	-4.1	-178.6	-60.4	-53.5	150.1	0	0	113.8	P243 L244 T248 S249 H250 W251	P243-E246 PolarHBondContact O-N 3.2Å; P243-E246 VanDerWaalsContact O-N 3.15Å; L244-E246 PolarHBondContact O-N 2.97Å; E246-T248 PolarHBondContact O-N 3.38Å; E246-S249 WeakPolarHBondContact CA-OG 3.39Å; E246-S249 PolarHBondContact O-OG 3.27Å; E246-S249 PolarHBondContact OE2-OG 3.18Å; E246-H250 PolarHBondContact O-N 3.27Å; E246-H250 VanDerWaalsContact O-N 3.1Å; E246-W251 VanDerWaalsContact O-CD1 3.25Å; E246-W251 PolarHBondContact O-N 3.23Å
247	Q	81.1	Confident	86.4	Confident	34 Å²	34	35.8 Å²	35.8	16%	0.159	21%	0.206	C	C	.	.	I	π-helix	trans	-65.7	-41.1	-175	-168.5	179.9	2.4	0	0	111.5	L244 R252 Y317	L244-Q247 WeakPolarHBondContact O-CB 3.46Å; L244-Q247 PolarHBondContact O-N 3.46Å; L244-Q247 VanDerWaalsContact O-N 3.13Å; Q247-R252 WeakPolarHBondContact O-CB 3.36Å; Q247-R252 PolarHBondContact O-N 2.9Å; Q247-Y317 HydrophobicContact CG-CD1 4.24Å
248	T	81.1	Confident	86.5	Confident	87 Å²	87	35.8 Å²	35.8	53%	0.534	21%	0.206	S	C	.	.	I	π-helix	trans	-87.6	-37.1	-177.6	53.6	0	0	0	0	113.4	E246 P253	E246-T248 PolarHBondContact O-N 3.38Å; T248-P253 WeakPolarHBondContact O-CD 3.26Å
249	S	84.5	Confident	86.5	Confident	69 Å²	69	35.8 Å²	35.8	48%	0.483	21%	0.206	S	C	.	.	I	π-helix	trans	-72	-46.1	-179.4	52.7	0	0	0	0	112.7	E246 P253	E246-S249 WeakPolarHBondContact CA-OG 3.39Å; E246-S249 PolarHBondContact O-OG 3.27Å; E246-S249 PolarHBondContact OE2-OG 3.18Å; S249-P253 VanDerWaalsContact O-CG 3.23Å; S249-P253 WeakPolarHBondContact O-CG 3.35Å
250	H	87.5	Confident	86.7	Confident	32 Å²	32	38.7 Å²	38.7	15%	0.148	22%	0.224	C	C	.	.	I	π-helix	trans	-117.7	-57.9	-168.6	-172.9	92.8	0	0	0	112.8	P220 Q224 E246 P253 A254	P220-H250 PolarHBondContact O-CE1 3.29Å; P220-H250 PolarHBondContact O-NE2 2.84Å; Q224-H250 HydrophobicContact CG-CB 4.45Å; Q224-H250 VanDerWaalsContact CG-CD2 3.43Å; Q224-H250 WeakPolarHBondContact CG-CD2 3.48Å; Q224-H250 VanDerWaalsContact CG-CE1 3.5Å; Q224-H250 WeakPolarHBondContact CG-CE1 3.21Å; Q224-H250 WeakPolarHBondContact CG-NE2 3.46Å; E246-H250 PolarHBondContact O-N 3.27Å; E246-H250 VanDerWaalsContact O-N 3.1Å; H250-P253 WeakPolarHBondContact O-CD 3.15Å; H250-P253 WeakPolarHBondContact O-CG 3.3Å; H250-A254 WeakPolarHBondContact O-CB 3.42Å; H250-A254 PolarHBondContact O-N 3.01Å
251	W	87.8	Confident	87.3	Confident	3 Å²	3	41.6 Å²	41.6	1%	0.011	24%	0.239	C	C	.	.	I	π-helix	trans	-69.3	-42.5	-168	-63.4	112.9	0	0	0	113.1	L221 Q224 Q226 L242 E246 A254 F255 Y317	L221-W251 HydrophobicContact CD2-CE3 4.49Å; L221-W251 HydrophobicContact CD2-CZ3 3.85Å; Q224-W251 HydrophobicContact CB-CH2 3.94Å; Q224-W251 HydrophobicContact CB-CZ2 3.56Å; Q224-W251 HydrophobicContact CG-CZ2 4.3Å; Q226-W251 HydrophobicContact CG-CH2 4Å; Q226-W251 HydrophobicContact CG-CZ2 4.4Å; L242-W251 HydrophobicContact CD1-CD2 3.91Å; L242-W251 HydrophobicContact CD1-CE3 4.35Å; L242-W251 HydrophobicContact CD1-CG 4.3Å; L242-W251 HydrophobicContact CD1-CH2 4.41Å; L242-W251 HydrophobicContact CD1-CZ2 3.98Å; L242-W251 HydrophobicContact CD2-CH2 4.48Å; L242-W251 HydrophobicContact CD2-CZ2 3.79Å; L242-W251 HydrophobicContact CG-CZ2 4.46Å; E246-W251 VanDerWaalsContact O-CD1 3.25Å; E246-W251 PolarHBondContact O-N 3.23Å; W251-A254 PolarHBondContact O-N 2.77Å; W251-F255 HydrophobicContact CB-CD2 4.12Å; W251-F255 HydrophobicContact CB-CE2 4.17Å; W251-F255 HydrophobicContact CD2-CE2 4.2Å; W251-F255 HydrophobicContact CE3-CD2 4.27Å; W251-F255 AromaticContact CE3-CE2 3.45Å; W251-F255 HydrophobicContact CE3-CE2 3.45Å; W251-F255 VanDerWaalsContact CE3-CE2 3.45Å; W251-F255 AromaticContact CE3-CZ 3.87Å; W251-F255 HydrophobicContact CE3-CZ 3.87Å; W251-F255 HydrophobicContact CZ3-CE2 4.19Å; W251-F255 HydrophobicContact CZ3-CZ 4.17Å; W251-F255 WeakPolarHBondContact O-CB 3.44Å; W251-F255 WeakPolarHBondContact O-CD2 3.21Å; W251-F255 PolarHBondContact O-N 3.42Å; W251-Y317 HydrophobicContact CB-CD1 3.84Å; W251-Y317 HydrophobicContact CB-CE1 3.7Å; W251-Y317 HydrophobicContact CG-CE1 4.36Å
252	R	88.9	Confident	87.8	Confident	108 Å²	108	41.5 Å²	41.5	41%	0.408	24%	0.238	S	C	.	.	H	α-helix	trans	-59.8	-54.3	176.5	178.5	173.8	-177.9	-149.6	0.9	113.6	Q247 A254 T256 Y317	Q247-R252 WeakPolarHBondContact O-CB 3.36Å; Q247-R252 PolarHBondContact O-N 2.9Å; R252-A254 VanDerWaalsContact C-N 3.35Å; R252-T256 VanDerWaalsContact O-CB 3.3Å; R252-T256 WeakPolarHBondContact O-CB 3.37Å; R252-T256 PolarHBondContact O-N 3.25Å; R252-T256 PolarHBondContact O-OG1 3.24Å; R252-Y317 WeakPolarHBondContact CB-O 3.5Å; R252-Y317 VanDerWaalsContact CD-O 3.31Å; R252-Y317 WeakPolarHBondContact CD-O 3.24Å; R252-Y317 WeakPolarHBondContact CG-O 3.41Å
253	P	91.1	Very high	88.4	Confident	43 Å²	43	41.1 Å²	41.1	28%	0.279	24%	0.236	S	C	.	.	H	α-helix	trans	-64.5	-38.2	177.4	21.6	-30.3	0	0	0	112.2	V10 T248 S249 H250 C257	V10-P253 HydrophobicContact CG1-CB 4.13Å; T248-P253 WeakPolarHBondContact O-CD 3.26Å; S249-P253 VanDerWaalsContact O-CG 3.23Å; S249-P253 WeakPolarHBondContact O-CG 3.35Å; H250-P253 WeakPolarHBondContact O-CD 3.15Å; H250-P253 WeakPolarHBondContact O-CG 3.3Å; P253-C257 VanDerWaalsContact O-CB 3.26Å; P253-C257 WeakPolarHBondContact O-CB 3.4Å; P253-C257 PolarHBondContact O-N 3.12Å
254	A	91.6	Very high	89.1	Confident	10 Å²	10	44 Å²	44	8%	0.083	25%	0.248	C	C	.	.	H	α-helix	trans	-58.3	-61.9	174.2	0	0	0	0	0	111.1	P220 H250 W251 R252 T256 C257 L258	P220-A254 HydrophobicContact CB-CB 4.17Å; H250-A254 WeakPolarHBondContact O-CB 3.42Å; H250-A254 PolarHBondContact O-N 3.01Å; W251-A254 PolarHBondContact O-N 2.77Å; R252-A254 VanDerWaalsContact C-N 3.35Å; A254-T256 VanDerWaalsContact C-N 3.27Å; A254-T256 PolarHBondContact O-N 3.21Å; A254-C257 WeakPolarHBondContact O-CA 3.39Å; A254-C257 VanDerWaalsContact O-CB 3.32Å; A254-C257 WeakPolarHBondContact O-CB 3.5Å; A254-C257 PolarHBondContact O-N 3.49Å; A254-L258 WeakPolarHBondContact O-CD1 3.24Å; A254-L258 PolarHBondContact O-N 3.19Å
255	F	91.4	Very high	90	Very high	0 Å²	0	45.1 Å²	45.1	0%	0	25%	0.254	C	S	.	.	H	α-helix	trans	-63.5	-30.2	-175.9	-72.4	-54.8	0	0	0	114.2	Y167 L221 H239 W251 L258 A259 L313 Y317	Y167-F255 HydrophobicContact CE1-CD1 4.36Å; Y167-F255 AromaticContact CE1-CE1 3.87Å; Y167-F255 HydrophobicContact CE1-CE1 3.87Å; Y167-F255 HydrophobicContact CE2-CE1 4.04Å; Y167-F255 HydrophobicContact CE2-CZ 4.48Å; Y167-F255 AromaticContact CZ-CE1 3.51Å; Y167-F255 VanDerWaalsContact OH-CE1 3.28Å; Y167-F255 WeakPolarHBondContact OH-CE1 3.3Å; L221-F255 HydrophobicContact CD2-CE1 3.71Å; L221-F255 HydrophobicContact CD2-CZ 3.86Å; H239-F255 AromaticContact CE1-CZ 3.7Å; H239-F255 AromaticContact NE2-CZ 3.76Å; W251-F255 HydrophobicContact CB-CD2 4.12Å; W251-F255 HydrophobicContact CB-CE2 4.17Å; W251-F255 HydrophobicContact CD2-CE2 4.2Å; W251-F255 HydrophobicContact CE3-CD2 4.27Å; W251-F255 AromaticContact CE3-CE2 3.45Å; W251-F255 HydrophobicContact CE3-CE2 3.45Å; W251-F255 VanDerWaalsContact CE3-CE2 3.45Å; W251-F255 AromaticContact CE3-CZ 3.87Å; W251-F255 HydrophobicContact CE3-CZ 3.87Å; W251-F255 HydrophobicContact CZ3-CE2 4.19Å; W251-F255 HydrophobicContact CZ3-CZ 4.17Å; W251-F255 WeakPolarHBondContact O-CB 3.44Å; W251-F255 WeakPolarHBondContact O-CD2 3.21Å; W251-F255 PolarHBondContact O-N 3.42Å; F255-L258 HydrophobicContact CD1-CD2 3.84Å; F255-L258 HydrophobicContact CE1-CD2 4.08Å; F255-A259 WeakPolarHBondContact O-CB 3.37Å; F255-A259 PolarHBondContact O-N 2.87Å; F255-L313 HydrophobicContact CB-CD1 4.36Å; F255-L313 HydrophobicContact CB-CD2 4.28Å; F255-L313 HydrophobicContact CB-CG 4.12Å; F255-L313 HydrophobicContact CD1-CD1 3.79Å; F255-L313 HydrophobicContact CD1-CD2 3.83Å; F255-L313 HydrophobicContact CD1-CG 4.11Å; F255-L313 HydrophobicContact CD2-CD1 4.43Å; F255-L313 HydrophobicContact CE1-CD1 4.13Å; F255-L313 HydrophobicContact CG-CD1 3.95Å; F255-L313 HydrophobicContact CG-CD2 4.35Å; F255-L313 HydrophobicContact CG-CG 4.21Å; F255-Y317 HydrophobicContact CB-CD2 4.11Å; F255-Y317 HydrophobicContact CB-CG 4.35Å; F255-Y317 AromaticContact CD2-CD1 3.85Å; F255-Y317 HydrophobicContact CD2-CD1 3.85Å; F255-Y317 AromaticContact CD2-CD2 3.37Å; F255-Y317 HydrophobicContact CD2-CD2 3.37Å; F255-Y317 AromaticContact CD2-CE1 3.79Å; F255-Y317 HydrophobicContact CD2-CE1 3.79Å; F255-Y317 AromaticContact CD2-CE2 3.31Å; F255-Y317 HydrophobicContact CD2-CE2 3.31Å; F255-Y317 AromaticContact CD2-CG 3.65Å; F255-Y317 HydrophobicContact CD2-CG 3.65Å; F255-Y317 AromaticContact CD2-CZ 3.53Å; F255-Y317 HydrophobicContact CE2-CD1 4.33Å; F255-Y317 AromaticContact CE2-CD2 3.98Å; F255-Y317 HydrophobicContact CE2-CD2 3.98Å; F255-Y317 AromaticContact CE2-CE1 3.79Å; F255-Y317 HydrophobicContact CE2-CE1 3.79Å; F255-Y317 AromaticContact CE2-CE2 3.39Å; F255-Y317 HydrophobicContact CE2-CE2 3.39Å; F255-Y317 HydrophobicContact CE2-CG 4.42Å; F255-Y317 AromaticContact CE2-CZ 3.28Å; F255-Y317 WeakPolarHBondContact CE2-OH 3.37Å; F255-Y317 AromaticContact CG-CD2 3.9Å; F255-Y317 HydrophobicContact CG-CD2 3.9Å; F255-Y317 HydrophobicContact CG-CE2 4.07Å; F255-Y317 HydrophobicContact CG-CG 4.36Å; F255-Y317 HydrophobicContact CZ-CE2 4.2Å
256	T	92.1	Very high	90.9	Very high	55 Å²	55	42.2 Å²	42.2	34%	0.337	23%	0.229	S	C	.	.	H	α-helix	trans	-64.9	-45.7	170.9	-54.3	0	0	0	0	111.2	R252 A254 A259 V260	R252-T256 VanDerWaalsContact O-CB 3.3Å; R252-T256 WeakPolarHBondContact O-CB 3.37Å; R252-T256 PolarHBondContact O-N 3.25Å; R252-T256 PolarHBondContact O-OG1 3.24Å; A254-T256 VanDerWaalsContact C-N 3.27Å; A254-T256 PolarHBondContact O-N 3.21Å; T256-A259 PolarHBondContact O-N 3.21Å; T256-V260 HydrophobicContact CG2-CG2 4.46Å; T256-V260 WeakPolarHBondContact O-CB 3.18Å; T256-V260 VanDerWaalsContact O-CG2 3.3Å; T256-V260 WeakPolarHBondContact O-CG2 3.15Å; T256-V260 PolarHBondContact O-N 3.26Å
257	C	93.2	Very high	91.7	Very high	48 Å²	48	39.7 Å²	39.7	32%	0.324	22%	0.218	S	C	.	.	H	α-helix	trans	-61.3	-46.4	176.5	-173.8	0	0	0	0	111.7	P253 A254 V260 L261	P253-C257 VanDerWaalsContact O-CB 3.26Å; P253-C257 WeakPolarHBondContact O-CB 3.4Å; P253-C257 PolarHBondContact O-N 3.12Å; A254-C257 WeakPolarHBondContact O-CA 3.39Å; A254-C257 VanDerWaalsContact O-CB 3.32Å; A254-C257 WeakPolarHBondContact O-CB 3.5Å; A254-C257 PolarHBondContact O-N 3.49Å; C257-V260 PolarHBondContact O-N 3.37Å; C257-L261 WeakPolarHBondContact O-CB 3.43Å; C257-L261 WeakPolarHBondContact O-CG 3.39Å; C257-L261 PolarHBondContact O-N 3.06Å; C257-L261 VanDerWaalsContact SG-CD1 3.54Å
258	L	93.9	Very high	92.4	Very high	1 Å²	1	43.5 Å²	43.5	1%	0.005	24%	0.239	C	C	.	.	H	α-helix	trans	-56.4	-51.5	175.6	-92.3	62.7	0	0	0	111.9	Y167 Y171 L217 L221 A254 F255 G262	Y167-L258 HydrophobicContact CD1-CD2 4.44Å; Y171-L258 HydrophobicContact CD2-CG 4.4Å; Y171-L258 WeakPolarHBondContact CE1-O 3.38Å; Y171-L258 HydrophobicContact CE2-CB 3.72Å; Y171-L258 HydrophobicContact CE2-CD2 3.8Å; Y171-L258 HydrophobicContact CE2-CG 3.68Å; L217-L258 HydrophobicContact CD2-CD1 4.49Å; L217-L258 VanDerWaalsContact O-CD1 3.26Å; L217-L258 WeakPolarHBondContact O-CD1 3.4Å; L221-L258 HydrophobicContact CD1-CD2 4.09Å; L221-L258 HydrophobicContact CD2-CD2 4.09Å; L221-L258 HydrophobicContact CG-CD2 4.31Å; A254-L258 WeakPolarHBondContact O-CD1 3.24Å; A254-L258 PolarHBondContact O-N 3.19Å; F255-L258 HydrophobicContact CD1-CD2 3.84Å; F255-L258 HydrophobicContact CE1-CD2 4.08Å; L258-G262 WeakPolarHBondContact O-CA 3.19Å; L258-G262 PolarHBondContact O-N 3.06Å
259	A	95.1	Very high	93.1	Very high	0 Å²	0	41.7 Å²	41.7	0%	0	23%	0.233	C	C	.	.	H	α-helix	trans	-66.1	-42	-179.5	0	0	0	0	0	112.8	F255 T256 C263 F264 N310 V314	F255-A259 WeakPolarHBondContact O-CB 3.37Å; F255-A259 PolarHBondContact O-N 2.87Å; T256-A259 PolarHBondContact O-N 3.21Å; A259-C263 WeakPolarHBondContact O-CA 3.33Å; A259-C263 VanDerWaalsContact O-CB 3.3Å; A259-C263 WeakPolarHBondContact O-CB 3.21Å; A259-C263 PolarHBondContact O-N 3Å; A259-C263 VanDerWaalsContact O-N 3.14Å; A259-F264 HydrophobicContact CB-CD2 4.38Å; A259-F264 HydrophobicContact CB-CE2 3.95Å; A259-F264 VanDerWaalsContact O-CD2 3.32Å; A259-F264 WeakPolarHBondContact O-CD2 3.4Å; A259-F264 PolarHBondContact O-N 3.01Å; A259-N310 HydrophobicContact CB-CB 4.21Å; A259-V314 HydrophobicContact CB-CG2 3.37Å
260	V	95.1	Very high	93.6	Very high	70 Å²	70	38.5 Å²	38.5	42%	0.424	21%	0.21	S	C	.	.	I	π-helix	trans	-70.2	-52.3	-179.2	173.3	0	0	0	0	111.8	T256 C257 F264 L265	T256-V260 HydrophobicContact CG2-CG2 4.46Å; T256-V260 WeakPolarHBondContact O-CB 3.18Å; T256-V260 VanDerWaalsContact O-CG2 3.3Å; T256-V260 WeakPolarHBondContact O-CG2 3.15Å; T256-V260 PolarHBondContact O-N 3.26Å; C257-V260 PolarHBondContact O-N 3.37Å; V260-F264 HydrophobicContact CG2-CD2 4.46Å; V260-L265 VanDerWaalsContact O-CB 3.25Å; V260-L265 WeakPolarHBondContact O-CB 3.45Å; V260-L265 PolarHBondContact O-N 3.38Å
261	L	95.1	Very high	93.9	Very high	81 Å²	81	38.4 Å²	38.4	42%	0.424	22%	0.218	S	C	.	.	I	π-helix	trans	-81	-34.7	-174.9	-59.8	-174.3	0	0	0	112.9	L217 C257 L265 P266	L217-L261 HydrophobicContact CD2-CB 4.07Å; L217-L261 HydrophobicContact CD2-CD1 4.34Å; C257-L261 WeakPolarHBondContact O-CB 3.43Å; C257-L261 WeakPolarHBondContact O-CG 3.39Å; C257-L261 PolarHBondContact O-N 3.06Å; C257-L261 VanDerWaalsContact SG-CD1 3.54Å; L261-L265 HydrophobicContact CD2-CD2 4.31Å; L261-P266 VanDerWaalsContact O-CD 3.25Å; L261-P266 WeakPolarHBondContact O-CD 3.3Å; L261-P266 WeakPolarHBondContact O-CG 3.49Å
262	G	93.3	Very high	94.2	Very high	0 Å²	0	42.8 Å²	42.8	0%	0	25%	0.245	C	C	.	.	I	π-helix	trans	-89.9	-25.3	-176.3	0	0	0	0	0	114.6	Y171 V174 L258	Y171-G262 VanDerWaalsContact CD1-CA 3.46Å; Y171-G262 WeakPolarHBondContact CD1-O 3.33Å; V174-G262 WeakPolarHBondContact CG1-O 3.49Å; L258-G262 WeakPolarHBondContact O-CA 3.19Å; L258-G262 PolarHBondContact O-N 3.06Å
263	C	95.9	Very high	94.3	Very high	0 Å²	0	38.4 Å²	38.4	0%	0	23%	0.23	C	C	.	.	I	π-helix	trans	-119.5	-65.3	-177.7	-172.4	0	0	0	0	113	Y171 A259 L265 P266 L267 N310	Y171-C263 HydrophobicContact CE1-CB 4.2Å; A259-C263 WeakPolarHBondContact O-CA 3.33Å; A259-C263 VanDerWaalsContact O-CB 3.3Å; A259-C263 WeakPolarHBondContact O-CB 3.21Å; A259-C263 PolarHBondContact O-N 3Å; A259-C263 VanDerWaalsContact O-N 3.14Å; C263-L265 PolarHBondContact O-N 3.04Å; C263-P266 WeakPolarHBondContact O-CD 3.41Å; C263-L267 WeakPolarHBondContact O-CB 3.5Å; C263-L267 VanDerWaalsContact O-CG 3.29Å; C263-L267 WeakPolarHBondContact O-CG 3.25Å; C263-L267 PolarHBondContact O-N 3.38Å; C263-L267 VanDerWaalsContact SG-CD1 3.58Å; C263-N310 HydrophobicContact CB-CB 4.08Å
264	F	97	Very high	94.3	Very high	69 Å²	69	39 Å²	39	30%	0.303	23%	0.228	S	C	.	.	I	π-helix	trans	-68.1	-41	-169.2	-59.8	-51.2	0	0	0	113.9	A259 V260 L267 L268 T307 N310 V311	A259-F264 HydrophobicContact CB-CD2 4.38Å; A259-F264 HydrophobicContact CB-CE2 3.95Å; A259-F264 VanDerWaalsContact O-CD2 3.32Å; A259-F264 WeakPolarHBondContact O-CD2 3.4Å; A259-F264 PolarHBondContact O-N 3.01Å; V260-F264 HydrophobicContact CG2-CD2 4.46Å; F264-L267 PolarHBondContact O-N 2.82Å; F264-L268 WeakPolarHBondContact O-CB 3.49Å; F264-L268 PolarHBondContact O-N 3.37Å; F264-T307 HydrophobicContact CE1-CG2 4.26Å; F264-N310 HydrophobicContact CZ-CB 4.14Å; F264-V311 HydrophobicContact CE1-CG2 4.08Å; F264-V311 HydrophobicContact CZ-CG2 3.87Å
265	L	96.3	Very high	94.3	Very high	99 Å²	99	39.9 Å²	39.9	52%	0.518	24%	0.238	S	C	.	.	H	α-helix	trans	-66.1	-46.2	177.7	175.1	67	0	0	0	112.5	V260 L261 C263 L268 A269	V260-L265 VanDerWaalsContact O-CB 3.25Å; V260-L265 WeakPolarHBondContact O-CB 3.45Å; V260-L265 PolarHBondContact O-N 3.38Å; L261-L265 HydrophobicContact CD2-CD2 4.31Å; C263-L265 PolarHBondContact O-N 3.04Å; L265-L268 PolarHBondContact O-N 3.43Å; L265-A269 PolarHBondContact O-N 3.24Å
266	P	96.2	Very high	94.2	Very high	8 Å²	8	40.4 Å²	40.4	5%	0.052	24%	0.242	C	C	.	.	H	α-helix	trans	-59.7	-44.1	170.2	-29.8	37.3	0	0	0	114.4	V174 L175 A178 L261 C263 L268 A269 M270	V174-P266 HydrophobicContact CG1-CB 3.41Å; V174-P266 VanDerWaalsContact CG1-CB 3.41Å; V174-P266 HydrophobicContact CG1-CG 3.96Å; L175-P266 HydrophobicContact CD2-CG 3.72Å; L175-P266 HydrophobicContact CG-CG 4.42Å; A178-P266 HydrophobicContact CB-CB 4.12Å; L261-P266 VanDerWaalsContact O-CD 3.25Å; L261-P266 WeakPolarHBondContact O-CD 3.3Å; L261-P266 WeakPolarHBondContact O-CG 3.49Å; C263-P266 WeakPolarHBondContact O-CD 3.41Å; P266-L268 VanDerWaalsContact C-N 3.31Å; P266-L268 PolarHBondContact O-N 3.09Å; P266-A269 WeakPolarHBondContact O-CB 3.41Å; P266-A269 PolarHBondContact O-N 3.37Å; P266-A269 VanDerWaalsContact O-N 3.11Å; P266-M270 WeakPolarHBondContact O-CG 3.07Å; P266-M270 PolarHBondContact O-N 2.8Å
267	L	96.3	Very high	94	Very high	17 Å²	17	38 Å²	38	9%	0.089	23%	0.227	C	C	.	.	H	α-helix	trans	-62.1	-38.6	177.5	-74.3	176.4	0	0	0	111.8	C263 F264 M270 G271 A302 V303	C263-L267 WeakPolarHBondContact O-CB 3.5Å; C263-L267 VanDerWaalsContact O-CG 3.29Å; C263-L267 WeakPolarHBondContact O-CG 3.25Å; C263-L267 PolarHBondContact O-N 3.38Å; C263-L267 VanDerWaalsContact SG-CD1 3.58Å; F264-L267 PolarHBondContact O-N 2.82Å; L267-M270 HydrophobicContact CD2-SD 4.15Å; L267-M270 PolarHBondContact O-N 3.37Å; L267-G271 PolarHBondContact O-N 3.08Å; L267-A302 HydrophobicContact CD2-CB 3.84Å; L267-V303 HydrophobicContact CD2-CG2 4.01Å
268	L	96.6	Very high	93.7	Very high	114 Å²	114	39 Å²	39	60%	0.597	23%	0.229	S	C	*	.	H	α-helix	trans	-61.3	-44.9	171.9	177.9	62.3	0	0	0	111.4	F264 L265 P266 M270 G271 V272	F264-L268 WeakPolarHBondContact O-CB 3.49Å; F264-L268 PolarHBondContact O-N 3.37Å; L265-L268 PolarHBondContact O-N 3.43Å; P266-L268 VanDerWaalsContact C-N 3.31Å; P266-L268 PolarHBondContact O-N 3.09Å; L268-M270 VanDerWaalsContact C-N 3.35Å; L268-M270 PolarHBondContact O-N 2.94Å; L268-G271 PolarHBondContact O-N 3.12Å; L268-V272 HydrophobicContact CD1-CG2 4.38Å; L268-V272 WeakPolarHBondContact O-CG2 3.45Å; L268-V272 PolarHBondContact O-N 2.86Å
269	A	95.4	Very high	93.4	Very high	49 Å²	49	47.8 Å²	47.8	41%	0.405	26%	0.262	S	S	.	.	H	α-helix	trans	-62	-40.7	176.5	0	0	0	0	0	112.2	L265 P266 V272 C273	L265-A269 PolarHBondContact O-N 3.24Å; P266-A269 WeakPolarHBondContact O-CB 3.41Å; P266-A269 PolarHBondContact O-N 3.37Å; P266-A269 VanDerWaalsContact O-N 3.11Å; A269-V272 PolarHBondContact O-N 2.9Å; A269-C273 WeakPolarHBondContact O-CB 3.37Å; A269-C273 PolarHBondContact O-N 2.82Å; A269-C273 PolarHBondContact O-SG 3.07Å
270	M	94.8	Very high	92.9	Very high	1 Å²	1	49.2 Å²	49.2	1%	0.005	27%	0.273	C	S	.	.	H	α-helix	trans	-61.8	-46.4	173.1	-67.7	171.7	69.1	0	0	111.6	L177 A178 P266 L267 L268 V272 C273 Y274 V298 L299 A302	L177-M270 HydrophobicContact CB-CE 4.03Å; L177-M270 HydrophobicContact CB-SD 4.32Å; A178-M270 HydrophobicContact CB-CG 3.84Å; A178-M270 HydrophobicContact CB-SD 4.23Å; P266-M270 WeakPolarHBondContact O-CG 3.07Å; P266-M270 PolarHBondContact O-N 2.8Å; L267-M270 HydrophobicContact CD2-SD 4.15Å; L267-M270 PolarHBondContact O-N 3.37Å; L268-M270 VanDerWaalsContact C-N 3.35Å; L268-M270 PolarHBondContact O-N 2.94Å; M270-V272 PolarHBondContact O-N 2.9Å; M270-C273 WeakPolarHBondContact O-CB 3.32Å; M270-C273 PolarHBondContact O-N 3.13Å; M270-Y274 WeakPolarHBondContact O-CB 3.46Å; M270-Y274 PolarHBondContact O-N 2.98Å; M270-V298 HydrophobicContact CE-CG1 3.88Å; M270-L299 HydrophobicContact CB-CD1 3.84Å; M270-L299 HydrophobicContact CE-CD1 4.41Å; M270-A302 HydrophobicContact CE-CB 3.84Å; M270-A302 HydrophobicContact SD-CB 4.44Å
271	G	94.7	Very high	92.1	Very high	30 Å²	30	46.6 Å²	46.6	31%	0.309	26%	0.257	S	S	.	.	H	α-helix	trans	-60.3	-42.7	177.2	0	0	0	0	0	113.1	L267 L268 Y274 G275	L267-G271 PolarHBondContact O-N 3.08Å; L268-G271 PolarHBondContact O-N 3.12Å; G271-Y274 PolarHBondContact O-N 3.16Å; G271-G275 PolarHBondContact O-N 3.07Å
272	V	94.1	Very high	91.6	Very high	95 Å²	95	47 Å²	47	58%	0.576	27%	0.272	S	S	*	.	H	α-helix	trans	-64.1	-44	174.5	171.5	0	0	0	0	111.4	L268 A269 M270 Y274 A276	L268-V272 HydrophobicContact CD1-CG2 4.38Å; L268-V272 WeakPolarHBondContact O-CG2 3.45Å; L268-V272 PolarHBondContact O-N 2.86Å; A269-V272 PolarHBondContact O-N 2.9Å; M270-V272 PolarHBondContact O-N 2.9Å; V272-Y274 PolarHBondContact O-N 2.84Å; V272-A276 VanDerWaalsContact O-CB 3.29Å; V272-A276 WeakPolarHBondContact O-CB 3.22Å; V272-A276 PolarHBondContact O-N 2.82Å
273	C	91.8	Very high	91.1	Very high	16 Å²	16	51.5 Å²	51.5	11%	0.108	31%	0.309	C	S	.	.	H	α-helix	trans	-60.3	-44.4	175.6	-71.9	0	0	0	0	111.9	Y185 A269 M270 T277	Y185-C273 HydrophobicContact CG-CB 4.36Å; A269-C273 WeakPolarHBondContact O-CB 3.37Å; A269-C273 PolarHBondContact O-N 2.82Å; A269-C273 PolarHBondContact O-SG 3.07Å; M270-C273 WeakPolarHBondContact O-CB 3.32Å; M270-C273 PolarHBondContact O-N 3.13Å; C273-T277 WeakPolarHBondContact O-CB 3.3Å; C273-T277 PolarHBondContact O-N 2.72Å; C273-T277 PolarHBondContact O-OG1 2.83Å
274	Y	90.7	Very high	90.1	Very high	57 Å²	57	54.7 Å²	54.7	22%	0.224	33%	0.332	C	S	.	.	H	α-helix	trans	-66.5	-49.2	178.6	-179.5	-112.1	0	0	0	112	M270 G271 V272 A276 T277 L278 L292 A296 L299	M270-Y274 WeakPolarHBondContact O-CB 3.46Å; M270-Y274 PolarHBondContact O-N 2.98Å; G271-Y274 PolarHBondContact O-N 3.16Å; V272-Y274 PolarHBondContact O-N 2.84Å; Y274-A276 VanDerWaalsContact C-N 3.31Å; Y274-A276 PolarHBondContact O-N 3.07Å; Y274-T277 WeakPolarHBondContact O-CA 3.04Å; Y274-T277 WeakPolarHBondContact O-CB 3.43Å; Y274-T277 PolarHBondContact O-N 2.86Å; Y274-T277 VanDerWaalsContact O-N 3.08Å; Y274-L278 HydrophobicContact CD1-CD1 3.96Å; Y274-L278 HydrophobicContact CE1-CD1 3.45Å; Y274-L278 VanDerWaalsContact CE1-CD1 3.45Å; Y274-L278 HydrophobicContact CE1-CG 4.19Å; Y274-L278 HydrophobicContact CE2-CG 4.39Å; Y274-L278 PolarHBondContact O-N 3.01Å; Y274-L292 HydrophobicContact CD2-CD1 4.35Å; Y274-L292 HydrophobicContact CE2-CD1 3.6Å; Y274-L292 HydrophobicContact CE2-CG 4.33Å; Y274-A296 HydrophobicContact CE2-CB 3.73Å; Y274-A296 WeakPolarHBondContact OH-CB 3.42Å; Y274-L299 HydrophobicContact CD1-CD2 3.69Å; Y274-L299 HydrophobicContact CE1-CD2 4.46Å; Y274-L299 HydrophobicContact CG-CD2 3.88Å
275	G	91	Very high	88.7	Confident	28 Å²	28	54.2 Å²	54.2	29%	0.289	35%	0.346	S	S	.	.	H	α-helix	trans	-62.5	-34.7	177.9	0	0	0	0	0	113.5	G271 R279	G271-G275 PolarHBondContact O-N 3.07Å; G275-R279 WeakPolarHBondContact O-CG 3.37Å; G275-R279 PolarHBondContact O-N 3.08Å
276	A	89.8	Confident	87.2	Confident	10 Å²	10	56.3 Å²	56.3	8%	0.083	35%	0.353	C	S	.	.	H	α-helix	trans	-72.5	-33.9	172.9	0	0	0	0	0	112.7	Y185 V272 Y274 A280	Y185-A276 HydrophobicContact CD2-CB 4.02Å; Y185-A276 HydrophobicContact CE2-CB 3.45Å; Y185-A276 VanDerWaalsContact CE2-CB 3.45Å; V272-A276 VanDerWaalsContact O-CB 3.29Å; V272-A276 WeakPolarHBondContact O-CB 3.22Å; V272-A276 PolarHBondContact O-N 2.82Å; Y274-A276 VanDerWaalsContact C-N 3.31Å; Y274-A276 PolarHBondContact O-N 3.07Å; A276-A280 PolarHBondContact O-N 3.04Å; A276-A280 VanDerWaalsContact O-N 3.14Å
277	T	86.7	Confident	85.6	Confident	6 Å²	6	65.6 Å²	65.6	4%	0.037	39%	0.387	C	S	.	.	H	α-helix	trans	-65.2	-43.6	172.9	-57.9	0	0	0	0	111.7	L188 C273 Y274 R279 A280 L281	L188-T277 HydrophobicContact CB-CG2 4.18Å; L188-T277 HydrophobicContact CD1-CG2 3.57Å; C273-T277 WeakPolarHBondContact O-CB 3.3Å; C273-T277 PolarHBondContact O-N 2.72Å; C273-T277 PolarHBondContact O-OG1 2.83Å; Y274-T277 WeakPolarHBondContact O-CA 3.04Å; Y274-T277 WeakPolarHBondContact O-CB 3.43Å; Y274-T277 PolarHBondContact O-N 2.86Å; Y274-T277 VanDerWaalsContact O-N 3.08Å; T277-R279 PolarHBondContact O-N 2.75Å; T277-A280 PolarHBondContact O-N 2.81Å; T277-L281 PolarHBondContact O-N 2.87Å
278	L	87.6	Confident	84.3	Confident	69 Å²	69	70.5 Å²	70.5	36%	0.361	41%	0.405	S	S	.	.	H	α-helix	trans	-56.6	-49.4	173.7	-83.1	171.1	0	0	0	112.2	Y274 A280 L281 A282 L292	Y274-L278 HydrophobicContact CD1-CD1 3.96Å; Y274-L278 HydrophobicContact CE1-CD1 3.45Å; Y274-L278 VanDerWaalsContact CE1-CD1 3.45Å; Y274-L278 HydrophobicContact CE1-CG 4.19Å; Y274-L278 HydrophobicContact CE2-CG 4.39Å; Y274-L278 PolarHBondContact O-N 3.01Å; L278-A280 PolarHBondContact O-N 3.18Å; L278-L281 PolarHBondContact O-N 3.15Å; L278-A282 WeakPolarHBondContact O-CB 3.27Å; L278-A282 PolarHBondContact O-N 3.35Å; L278-L292 HydrophobicContact CD2-CD1 3.57Å; L278-L292 HydrophobicContact CD2-CD2 3.74Å; L278-L292 HydrophobicContact CD2-CG 4.25Å; L278-L292 HydrophobicContact CG-CD1 3.93Å
279	R	87.6	Confident	83.1	Confident	185 Å²	185	68.5 Å²	68.5	70%	0.698	40%	0.401	S	S	*	.	H	α-helix	trans	-60.9	-42.3	179.2	-73	-172.7	-64.3	147.3	-3	112.4	G275 T277 A282 A283	G275-R279 WeakPolarHBondContact O-CG 3.37Å; G275-R279 PolarHBondContact O-N 3.08Å; T277-R279 PolarHBondContact O-N 2.75Å; R279-A282 PolarHBondContact O-N 3Å; R279-A283 PolarHBondContact O-N 3.47Å; R279-A283 VanDerWaalsContact O-N 3.17Å
280	A	83.9	Confident	82.1	Confident	29 Å²	29	71.2 Å²	71.2	24%	0.24	41%	0.405	C	S	.	.	H	α-helix	trans	-65	-38	176.9	0	0	0	0	0	112.4	V189 A276 T277 L278 A283 S284	V189-A280 HydrophobicContact CB-CB 4.28Å; V189-A280 HydrophobicContact CG1-CB 4.03Å; V189-A280 HydrophobicContact CG2-CB 3.79Å; A276-A280 PolarHBondContact O-N 3.04Å; A276-A280 VanDerWaalsContact O-N 3.14Å; T277-A280 PolarHBondContact O-N 2.81Å; L278-A280 PolarHBondContact O-N 3.18Å; A280-A283 PolarHBondContact O-N 3.24Å; A280-S284 WeakPolarHBondContact O-CB 3.13Å; A280-S284 PolarHBondContact O-N 3.03Å; A280-S284 PolarHBondContact O-OG 3.32Å
281	L	80.1	Confident	81.3	Confident	16 Å²	16	72.1 Å²	72.1	8%	0.084	41%	0.413	C	S	.	.	H	α-helix	trans	-71.4	-38.7	178	-173.8	60.7	0	0	0	112.5	T277 L278 A283 S284 G285 Y288 L292	T277-L281 PolarHBondContact O-N 2.87Å; L278-L281 PolarHBondContact O-N 3.15Å; L281-A283 VanDerWaalsContact C-N 3.28Å; L281-A283 PolarHBondContact O-N 3Å; L281-S284 WeakPolarHBondContact CA-OG 3.28Å; L281-S284 PolarHBondContact O-N 3.44Å; L281-S284 VanDerWaalsContact O-N 3.16Å; L281-S284 PolarHBondContact O-OG 3.11Å; L281-G285 PolarHBondContact O-N 2.91Å; L281-Y288 HydrophobicContact CD1-CD2 4.2Å; L281-L292 HydrophobicContact CD2-CB 4.13Å; L281-L292 HydrophobicContact CD2-CD2 4.01Å; L281-L292 HydrophobicContact CD2-CG 4.49Å
282	A	83.3	Confident	80.6	Confident	88 Å²	88	72.2 Å²	72.2	73%	0.727	41%	0.406	S	S	*	.	H	α-helix	trans	-59.8	-39.4	173.9	0	0	0	0	0	111.7	L278 R279 S284	L278-A282 WeakPolarHBondContact O-CB 3.27Å; L278-A282 PolarHBondContact O-N 3.35Å; R279-A282 PolarHBondContact O-N 3Å; A282-S284 VanDerWaalsContact C-N 3.35Å
283	A	83.3	Confident	80	Confident	95 Å²	95	74 Å²	74	79%	0.785	40%	0.403	S	S	*	.	H	α-helix	trans	-75.2	-16.2	176.6	0	0	0	0	0	114.8	R279 A280 L281	R279-A283 PolarHBondContact O-N 3.47Å; R279-A283 VanDerWaalsContact O-N 3.17Å; A280-A283 PolarHBondContact O-N 3.24Å; L281-A283 VanDerWaalsContact C-N 3.28Å; L281-A283 PolarHBondContact O-N 3Å
284	S	76	Confident	79.5	Confident	68 Å²	68	74.1 Å²	74.1	48%	0.476	40%	0.402	S	S	.	.	H	α-helix	trans	-116.4	6.2	-171.4	57.4	0	0	0	0	115.5	A280 L281 A282	A280-S284 WeakPolarHBondContact O-CB 3.13Å; A280-S284 PolarHBondContact O-N 3.03Å; A280-S284 PolarHBondContact O-OG 3.32Å; L281-S284 WeakPolarHBondContact CA-OG 3.28Å; L281-S284 PolarHBondContact O-N 3.44Å; L281-S284 VanDerWaalsContact O-N 3.16Å; L281-S284 PolarHBondContact O-OG 3.11Å; A282-S284 VanDerWaalsContact C-N 3.35Å
285	G	66.8	Low	79.1	Confident	59 Å²	59	71.9 Å²	71.9	61%	0.608	39%	0.394	S	S	*	.	T	Hydrogen-bonded Turn	trans	73	62.2	168.9	0	0	0	0	0	114.9	L281 R287	L281-G285 PolarHBondContact O-N 2.91Å; G285-R287 PolarHBondContact O-N 3.1Å
286	Q	64.5	Low	78.9	Confident	142 Å²	142	71.9 Å²	71.9	66%	0.664	39%	0.391	S	S	*	.	S	Bend	trans	61.9	9.1	161.8	-72.9	-71.8	-5.1	0	0	118.3	Y288	Q286-Y288 PolarHBondContact O-N 3.43Å
287	R	63.3	Low	78.8	Confident	204 Å²	204	74.6 Å²	74.6	77%	0.77	40%	0.404	S	S	*	.	T	Hydrogen-bonded Turn	trans	-64.8	-6.6	-172.5	-147.4	171.2	-169.9	162.8	3.2	116.7	G285	G285-R287 PolarHBondContact O-N 3.1Å
288	Y	68.5	Low	78.9	Confident	119 Å²	119	74.6 Å²	74.6	47%	0.467	40%	0.404	S	S	.	.	T	Hydrogen-bonded Turn	trans	-139.4	32.1	-170.9	-57.8	-70.7	0	0	0	115.6	L188 L281 Q286 H290 A291 L292	L188-Y288 HydrophobicContact CD2-CD1 3.93Å; L188-Y288 HydrophobicContact CD2-CD2 4.15Å; L188-Y288 HydrophobicContact CD2-CE1 4.46Å; L188-Y288 HydrophobicContact CD2-CG 3.76Å; L281-Y288 HydrophobicContact CD1-CD2 4.2Å; Q286-Y288 PolarHBondContact O-N 3.43Å; Y288-H290 VanDerWaalsContact C-N 3.29Å; Y288-H290 PolarHBondContact O-N 2.95Å; Y288-A291 PolarHBondContact O-N 2.98Å; Y288-A291 VanDerWaalsContact O-N 3.1Å; Y288-L292 PolarHBondContact O-N 3.48Å; Y288-L292 VanDerWaalsContact O-N 3.1Å
289	S	71.8	Confident	79.1	Confident	73 Å²	73	72.7 Å²	72.7	51%	0.51	39%	0.394	S	S	.	.	H	α-helix	trans	-51	-40.4	-177.9	59.5	0	0	0	0	114.8	L292 R293	S289-L292 PolarHBondContact O-N 3.32Å; S289-R293 PolarHBondContact O-N 2.89Å
290	H	74.9	Confident	79.3	Confident	106 Å²	106	66.6 Å²	66.6	49%	0.491	38%	0.383	S	S	.	.	H	α-helix	trans	-64.3	-43.8	178	-175.6	-97.9	0	0	0	113	Y288 L292 R293 L294 Y352	Y288-H290 VanDerWaalsContact C-N 3.29Å; Y288-H290 PolarHBondContact O-N 2.95Å; H290-L292 VanDerWaalsContact C-N 3.31Å; H290-L292 PolarHBondContact O-N 3.01Å; H290-R293 PolarHBondContact O-N 3.12Å; H290-L294 PolarHBondContact O-N 3Å; H290-L294 VanDerWaalsContact O-N 3.1Å; H290-Y352 PolarHBondContact CE1-O 3.45Å; H290-Y352 AromaticContact NE2-CD1 3.93Å
291	A	76.3	Confident	79.7	Confident	20 Å²	20	65.8 Å²	65.8	17%	0.165	38%	0.376	C	S	.	.	H	α-helix	trans	-67.8	-34.6	178.4	0	0	0	0	0	111.5	L188 Y288 L294 T295	L188-A291 HydrophobicContact CD1-CB 4.04Å; L188-A291 HydrophobicContact CD2-CB 4.28Å; Y288-A291 PolarHBondContact O-N 2.98Å; Y288-A291 VanDerWaalsContact O-N 3.1Å; A291-L294 PolarHBondContact O-N 3.19Å; A291-T295 PolarHBondContact O-N 3.08Å; A291-T295 PolarHBondContact O-OG1 3.15Å
292	L	80.5	Confident	80.2	Confident	32 Å²	32	65 Å²	65	17%	0.168	37%	0.372	C	S	.	.	H	α-helix	trans	-62.4	-50.6	172.6	-176.6	74.2	0	0	0	111.3	Y274 L278 L281 Y288 S289 H290 L294 T295 A296	Y274-L292 HydrophobicContact CD2-CD1 4.35Å; Y274-L292 HydrophobicContact CE2-CD1 3.6Å; Y274-L292 HydrophobicContact CE2-CG 4.33Å; L278-L292 HydrophobicContact CD2-CD1 3.57Å; L278-L292 HydrophobicContact CD2-CD2 3.74Å; L278-L292 HydrophobicContact CD2-CG 4.25Å; L278-L292 HydrophobicContact CG-CD1 3.93Å; L281-L292 HydrophobicContact CD2-CB 4.13Å; L281-L292 HydrophobicContact CD2-CD2 4.01Å; L281-L292 HydrophobicContact CD2-CG 4.49Å; Y288-L292 PolarHBondContact O-N 3.48Å; Y288-L292 VanDerWaalsContact O-N 3.1Å; S289-L292 PolarHBondContact O-N 3.32Å; H290-L292 VanDerWaalsContact C-N 3.31Å; H290-L292 PolarHBondContact O-N 3.01Å; L292-L294 PolarHBondContact O-N 3.4Å; L292-T295 WeakPolarHBondContact CA-OG1 3.38Å; L292-T295 PolarHBondContact O-N 3.15Å; L292-T295 VanDerWaalsContact O-N 3.1Å; L292-T295 PolarHBondContact O-OG1 3.47Å; L292-A296 WeakPolarHBondContact O-CB 3.36Å; L292-A296 PolarHBondContact O-N 3.04Å
293	R	82.1	Confident	80.8	Confident	133 Å²	133	63.9 Å²	63.9	50%	0.502	36%	0.356	S	S	.	.	H	α-helix	trans	-55.8	-41.2	178.7	-174.3	178.4	178.7	-162.3	-3.5	111.6	S289 H290 A296 L297 L394	S289-R293 PolarHBondContact O-N 2.89Å; H290-R293 PolarHBondContact O-N 3.12Å; R293-A296 PolarHBondContact O-N 2.85Å; R293-L297 WeakPolarHBondContact O-CB 3.37Å; R293-L297 PolarHBondContact O-N 2.96Å; R293-L394 PolarHBondContact NH1-OXT 2.89Å; R293-L394 PolarHBondContact NH2-OXT 3.36Å
294	L	81.8	Confident	81.3	Confident	18 Å²	18	62.6 Å²	62.6	9%	0.094	35%	0.345	C	S	.	.	H	α-helix	trans	-62.3	-50	174.4	-176.9	67.4	0	0	0	112.2	H290 A291 L292 A296 L297 V298 I349 V353	H290-L294 PolarHBondContact O-N 3Å; H290-L294 VanDerWaalsContact O-N 3.1Å; A291-L294 PolarHBondContact O-N 3.19Å; L292-L294 PolarHBondContact O-N 3.4Å; L294-A296 VanDerWaalsContact C-N 3.28Å; L294-A296 PolarHBondContact O-N 3.05Å; L294-L297 PolarHBondContact O-N 2.7Å; L294-V298 WeakPolarHBondContact O-CG2 3.44Å; L294-V298 PolarHBondContact O-N 3.38Å; L294-I349 HydrophobicContact CD1-CG2 4.07Å; L294-V353 HydrophobicContact CD1-CG2 4.47Å; L294-V353 HydrophobicContact CD2-CG2 3.42Å; L294-V353 VanDerWaalsContact CD2-CG2 3.42Å
295	T	81.9	Confident	82.1	Confident	10 Å²	10	60.3 Å²	60.3	6%	0.061	33%	0.329	C	S	.	.	H	α-helix	trans	-63.7	-33.5	178.1	50.9	0	0	0	0	113.2	R184 A291 L292 L299	R184-T295 HydrophobicContact CB-CG2 3.68Å; R184-T295 HydrophobicContact CG-CG2 3.8Å; A291-T295 PolarHBondContact O-N 3.08Å; A291-T295 PolarHBondContact O-OG1 3.15Å; L292-T295 WeakPolarHBondContact CA-OG1 3.38Å; L292-T295 PolarHBondContact O-N 3.15Å; L292-T295 VanDerWaalsContact O-N 3.1Å; L292-T295 PolarHBondContact O-OG1 3.47Å; T295-L299 WeakPolarHBondContact O-CB 3.4Å; T295-L299 PolarHBondContact O-N 2.92Å
296	A	87.2	Confident	83.4	Confident	28 Å²	28	57.5 Å²	57.5	23%	0.231	30%	0.3	C	S	.	.	H	α-helix	trans	-67.9	-43.5	175.3	0	0	0	0	0	111.5	Y274 L292 R293 L294 L299 A300	Y274-A296 HydrophobicContact CE2-CB 3.73Å; Y274-A296 WeakPolarHBondContact OH-CB 3.42Å; L292-A296 WeakPolarHBondContact O-CB 3.36Å; L292-A296 PolarHBondContact O-N 3.04Å; R293-A296 PolarHBondContact O-N 2.85Å; L294-A296 VanDerWaalsContact C-N 3.28Å; L294-A296 PolarHBondContact O-N 3.05Å; A296-L299 PolarHBondContact O-N 2.94Å; A296-A300 VanDerWaalsContact O-CB 3.25Å; A296-A300 WeakPolarHBondContact O-CB 3.41Å; A296-A300 PolarHBondContact O-N 2.96Å
297	L	87	Confident	84.8	Confident	67 Å²	67	52.5 Å²	52.5	35%	0.351	28%	0.279	S	S	.	.	H	α-helix	trans	-60.8	-45.6	176.4	-177.8	65.7	0	0	0	111.4	R293 L294 A300 S301	R293-L297 WeakPolarHBondContact O-CB 3.37Å; R293-L297 PolarHBondContact O-N 2.96Å; L294-L297 PolarHBondContact O-N 2.7Å; L297-A300 PolarHBondContact O-N 2.93Å; L297-S301 PolarHBondContact O-N 2.97Å; L297-S301 PolarHBondContact O-OG 2.89Å
298	V	88.5	Confident	86.3	Confident	5 Å²	5	45.4 Å²	45.4	3%	0.03	26%	0.26	C	S	.	.	H	α-helix	trans	-61.6	-43.8	177.1	167.4	0	0	0	0	112.2	L177 M270 L294 S301 A302 I349	L177-V298 HydrophobicContact CB-CG1 4.44Å; L177-V298 HydrophobicContact CD2-CG1 4.06Å; M270-V298 HydrophobicContact CE-CG1 3.88Å; L294-V298 WeakPolarHBondContact O-CG2 3.44Å; L294-V298 PolarHBondContact O-N 3.38Å; V298-S301 PolarHBondContact O-OG 2.63Å; V298-A302 WeakPolarHBondContact O-CB 3.38Å; V298-A302 PolarHBondContact O-N 2.77Å; V298-I349 HydrophobicContact CG2-CD1 3.72Å; V298-I349 HydrophobicContact CG2-CG1 3.91Å; V298-I349 HydrophobicContact CG2-CG2 4.28Å
299	L	91.6	Very high	87.5	Confident	29 Å²	29	39.9 Å²	39.9	15%	0.152	24%	0.238	C	C	.	.	H	α-helix	trans	-66.7	-42.6	175.8	178.2	61.4	0	0	0	111.3	M270 Y274 T295 A296 V303	M270-L299 HydrophobicContact CB-CD1 3.84Å; M270-L299 HydrophobicContact CE-CD1 4.41Å; Y274-L299 HydrophobicContact CD1-CD2 3.69Å; Y274-L299 HydrophobicContact CE1-CD2 4.46Å; Y274-L299 HydrophobicContact CG-CD2 3.88Å; T295-L299 WeakPolarHBondContact O-CB 3.4Å; T295-L299 PolarHBondContact O-N 2.92Å; A296-L299 PolarHBondContact O-N 2.94Å; L299-V303 HydrophobicContact CD1-CG2 3.96Å; L299-V303 HydrophobicContact CG-CG2 4.43Å; L299-V303 WeakPolarHBondContact O-CB 3.34Å; L299-V303 VanDerWaalsContact O-CG2 3.26Å; L299-V303 WeakPolarHBondContact O-CG2 3.36Å; L299-V303 PolarHBondContact O-N 3.37Å
300	A	92.1	Very high	88.6	Confident	57 Å²	57	36.4 Å²	36.4	47%	0.471	21%	0.214	S	C	.	.	H	α-helix	trans	-65.6	-42.5	-179.6	0	0	0	0	0	112.4	A296 L297 A304	A296-A300 VanDerWaalsContact O-CB 3.25Å; A296-A300 WeakPolarHBondContact O-CB 3.41Å; A296-A300 PolarHBondContact O-N 2.96Å; L297-A300 PolarHBondContact O-N 2.93Å; A300-A304 WeakPolarHBondContact O-CB 3.48Å; A300-A304 PolarHBondContact O-N 3.06Å
301	S	91.4	Very high	89.4	Confident	12 Å²	12	34.2 Å²	34.2	8%	0.084	21%	0.208	C	C	.	.	H	α-helix	trans	-65.9	-43.9	177.3	70.1	0	0	0	0	111.5	L297 V298 A304 S305 N342	L297-S301 PolarHBondContact O-N 2.97Å; L297-S301 PolarHBondContact O-OG 2.89Å; V298-S301 PolarHBondContact O-OG 2.63Å; S301-A304 PolarHBondContact O-N 3.23Å; S301-S305 VanDerWaalsContact O-CB 3.23Å; S301-S305 WeakPolarHBondContact O-CB 3.13Å; S301-S305 PolarHBondContact O-N 3.48Å; S301-S305 PolarHBondContact O-OG 3.27Å; S301-N342 PolarHBondContact OG-OD1 3.18Å
302	A	92.2	Very high	90.1	Very high	0 Å²	0	34.8 Å²	34.8	0%	0	21%	0.208	C	C	.	.	H	α-helix	trans	-63.3	-45.4	177.6	0	0	0	0	0	111.9	L177 L267 M270 V298 F306	L177-A302 HydrophobicContact CD1-CB 4.22Å; L267-A302 HydrophobicContact CD2-CB 3.84Å; M270-A302 HydrophobicContact CE-CB 3.84Å; M270-A302 HydrophobicContact SD-CB 4.44Å; V298-A302 WeakPolarHBondContact O-CB 3.38Å; V298-A302 PolarHBondContact O-N 2.77Å; A302-F306 HydrophobicContact CB-CD2 3.98Å; A302-F306 HydrophobicContact CB-CE2 4.15Å; A302-F306 WeakPolarHBondContact O-CB 3.36Å; A302-F306 WeakPolarHBondContact O-CD2 3.46Å; A302-F306 PolarHBondContact O-N 2.91Å
303	V	94.6	Very high	90.6	Very high	64 Å²	64	33.3 Å²	33.3	39%	0.388	20%	0.2	S	C	.	.	H	α-helix	trans	-62.7	-47.8	176.3	169.8	0	0	0	0	110.8	L267 L299 S305 T307	L267-V303 HydrophobicContact CD2-CG2 4.01Å; L299-V303 HydrophobicContact CD1-CG2 3.96Å; L299-V303 HydrophobicContact CG-CG2 4.43Å; L299-V303 WeakPolarHBondContact O-CB 3.34Å; L299-V303 VanDerWaalsContact O-CG2 3.26Å; L299-V303 WeakPolarHBondContact O-CG2 3.36Å; L299-V303 PolarHBondContact O-N 3.37Å; V303-S305 PolarHBondContact O-N 3.25Å; V303-T307 WeakPolarHBondContact CA-OG1 3.29Å; V303-T307 WeakPolarHBondContact O-CB 3.44Å; V303-T307 PolarHBondContact O-N 3.46Å; V303-T307 VanDerWaalsContact O-N 3.14Å; V303-T307 PolarHBondContact O-OG1 2.89Å
304	A	93.3	Very high	90.9	Very high	68 Å²	68	29 Å²	29	56%	0.562	19%	0.189	S	C	*	.	H	α-helix	trans	-66.8	-36.5	-177.8	0	0	0	0	0	113.2	A300 S301 P308	A300-A304 WeakPolarHBondContact O-CB 3.48Å; A300-A304 PolarHBondContact O-N 3.06Å; S301-A304 PolarHBondContact O-N 3.23Å; A304-P308 VanDerWaalsContact O-CD 3.27Å; A304-P308 WeakPolarHBondContact O-CD 3.39Å; A304-P308 WeakPolarHBondContact O-CG 3.14Å
305	S	92.8	Very high	91.1	Very high	20 Å²	20	30.2 Å²	30.2	14%	0.14	20%	0.195	C	C	.	.	H	α-helix	trans	-82.5	-44.2	-176.8	-53.2	0	0	0	0	112.4	S301 V303 S339	S301-S305 VanDerWaalsContact O-CB 3.23Å; S301-S305 WeakPolarHBondContact O-CB 3.13Å; S301-S305 PolarHBondContact O-N 3.48Å; S301-S305 PolarHBondContact O-OG 3.27Å; V303-S305 PolarHBondContact O-N 3.25Å; S305-S339 WeakPolarHBondContact O-CA 3.46Å; S305-S339 WeakPolarHBondContact O-CB 3.48Å
306	F	94.4	Very high	91	Very high	0 Å²	0	30.9 Å²	30.9	0%	0	20%	0.198	C	C	.	.	H	α-helix	trans	-100.4	-26.1	-168.4	-52.4	-59	0	0	0	114.4	M170 V174 L177 A302 S309 N310 N342	M170-F306 HydrophobicContact CG-CD1 3.56Å; M170-F306 HydrophobicContact CG-CE1 3.86Å; M170-F306 HydrophobicContact SD-CD1 4.17Å; V174-F306 HydrophobicContact CG2-CB 4.08Å; V174-F306 HydrophobicContact CG2-CD1 4.09Å; V174-F306 HydrophobicContact CG2-CD2 3.19Å; V174-F306 HydrophobicContact CG2-CE1 4.32Å; V174-F306 HydrophobicContact CG2-CE2 3.49Å; V174-F306 VanDerWaalsContact CG2-CE2 3.49Å; V174-F306 HydrophobicContact CG2-CG 3.52Å; V174-F306 HydrophobicContact CG2-CZ 4.03Å; L177-F306 HydrophobicContact CD1-CE2 4.11Å; A302-F306 HydrophobicContact CB-CD2 3.98Å; A302-F306 HydrophobicContact CB-CE2 4.15Å; A302-F306 WeakPolarHBondContact O-CB 3.36Å; A302-F306 WeakPolarHBondContact O-CD2 3.46Å; A302-F306 PolarHBondContact O-N 2.91Å; F306-S309 PolarHBondContact O-OG 3.25Å; F306-S309 VanDerWaalsContact O-OG 3.14Å; F306-N310 WeakPolarHBondContact O-CB 3.5Å; F306-N310 PolarHBondContact O-N 3.49Å; F306-N310 PolarHBondContact O-ND2 3.12Å; F306-N342 HydrophobicContact CE1-CB 4.12Å; F306-N342 HydrophobicContact CE2-CB 4.19Å; F306-N342 HydrophobicContact CZ-CB 3.57Å
307	T	94.4	Very high	90.6	Very high	37 Å²	37	30.3 Å²	30.3	23%	0.227	19%	0.189	C	C	.	.	H	α-helix	trans	-66.5	-47.9	-179.5	-44.9	0	0	0	0	112.2	F264 V303 S309 N310 V311	F264-T307 HydrophobicContact CE1-CG2 4.26Å; V303-T307 WeakPolarHBondContact CA-OG1 3.29Å; V303-T307 WeakPolarHBondContact O-CB 3.44Å; V303-T307 PolarHBondContact O-N 3.46Å; V303-T307 VanDerWaalsContact O-N 3.14Å; V303-T307 PolarHBondContact O-OG1 2.89Å; T307-S309 PolarHBondContact O-N 3.07Å; T307-N310 PolarHBondContact O-N 3.28Å; T307-V311 HydrophobicContact CG2-CG2 4.04Å; T307-V311 WeakPolarHBondContact O-CB 3.31Å; T307-V311 VanDerWaalsContact O-CG2 3.29Å; T307-V311 WeakPolarHBondContact O-CG2 3.23Å; T307-V311 PolarHBondContact O-N 3.49Å
308	P	94.4	Very high	90.1	Very high	56 Å²	56	28.7 Å²	28.7	36%	0.364	18%	0.184	S	C	.	.	H	α-helix	trans	-61.9	-42.9	-177.3	-24	36.3	0	0	0	112.4	A304 L312 S335	A304-P308 VanDerWaalsContact O-CD 3.27Å; A304-P308 WeakPolarHBondContact O-CD 3.39Å; A304-P308 WeakPolarHBondContact O-CG 3.14Å; P308-L312 WeakPolarHBondContact O-CB 3.43Å; P308-L312 WeakPolarHBondContact O-CD1 3.42Å; P308-L312 VanDerWaalsContact O-CG 3.28Å; P308-L312 WeakPolarHBondContact O-CG 3.24Å; P308-L312 PolarHBondContact O-N 3.33Å; P308-S335 WeakPolarHBondContact CB-OG 3.45Å
309	S	93.8	Very high	88.8	Confident	2 Å²	2	34.4 Å²	34.4	1%	0.014	21%	0.214	C	C	.	.	H	α-helix	trans	-66.2	-42.2	-179.8	59.5	0	0	0	0	111.9	F306 T307 L313 S335	F306-S309 PolarHBondContact O-OG 3.25Å; F306-S309 VanDerWaalsContact O-OG 3.14Å; T307-S309 PolarHBondContact O-N 3.07Å; S309-L313 WeakPolarHBondContact O-CB 3.46Å; S309-L313 PolarHBondContact O-N 2.78Å; S309-S335 WeakPolarHBondContact CA-OG 3.19Å; S309-S335 PolarHBondContact N-OG 3.44Å; S309-S335 VanDerWaalsContact N-OG 3.09Å
310	N	94.9	Very high	87	Confident	0 Å²	0	35.4 Å²	35.4	0%	0	22%	0.222	C	C	.	.	H	α-helix	trans	-74.7	-33	-179.9	-76.2	-90.4	0	0	0	113	Y171 A259 C263 F264 F306 T307 V314	Y171-N310 WeakPolarHBondContact CE1-OD1 3.5Å; Y171-N310 PolarHBondContact OH-OD1 3.21Å; A259-N310 HydrophobicContact CB-CB 4.21Å; C263-N310 HydrophobicContact CB-CB 4.08Å; F264-N310 HydrophobicContact CZ-CB 4.14Å; F306-N310 WeakPolarHBondContact O-CB 3.5Å; F306-N310 PolarHBondContact O-N 3.49Å; F306-N310 PolarHBondContact O-ND2 3.12Å; T307-N310 PolarHBondContact O-N 3.28Å; N310-V314 WeakPolarHBondContact O-CG2 3.36Å; N310-V314 PolarHBondContact O-N 2.67Å
311	V	93.3	Very high	84.8	Confident	60 Å²	60	36 Å²	36	36%	0.364	22%	0.223	S	C	.	.	H	α-helix	trans	-64.9	-48.2	170.8	169.5	0	0	0	0	110.3	F264 T307 L313 V314 L315	F264-V311 HydrophobicContact CE1-CG2 4.08Å; F264-V311 HydrophobicContact CZ-CG2 3.87Å; T307-V311 HydrophobicContact CG2-CG2 4.04Å; T307-V311 WeakPolarHBondContact O-CB 3.31Å; T307-V311 VanDerWaalsContact O-CG2 3.29Å; T307-V311 WeakPolarHBondContact O-CG2 3.23Å; T307-V311 PolarHBondContact O-N 3.49Å; V311-L313 VanDerWaalsContact C-N 3.33Å; V311-L313 PolarHBondContact O-N 2.89Å; V311-V314 PolarHBondContact O-N 2.87Å; V311-L315 HydrophobicContact CG1-CD1 3.86Å; V311-L315 HydrophobicContact CG1-CG 4.45Å; V311-L315 WeakPolarHBondContact O-CB 3.42Å; V311-L315 VanDerWaalsContact O-CG 3.3Å; V311-L315 WeakPolarHBondContact O-CG 3.27Å; V311-L315 PolarHBondContact O-N 2.95Å
312	L	90.8	Very high	82.6	Confident	32 Å²	32	37.4 Å²	37.4	17%	0.168	23%	0.232	C	C	.	.	H	α-helix	trans	-64.1	-36.8	177.6	-72.6	167.2	0	0	0	112.4	P308 L315 H316 L328 A331 Y332	P308-L312 WeakPolarHBondContact O-CB 3.43Å; P308-L312 WeakPolarHBondContact O-CD1 3.42Å; P308-L312 VanDerWaalsContact O-CG 3.28Å; P308-L312 WeakPolarHBondContact O-CG 3.24Å; P308-L312 PolarHBondContact O-N 3.33Å; L312-L315 PolarHBondContact O-N 2.69Å; L312-H316 WeakPolarHBondContact O-CB 3.04Å; L312-H316 PolarHBondContact O-N 2.56Å; L312-L328 HydrophobicContact CD2-CD2 3.84Å; L312-A331 HydrophobicContact CD1-CB 4.06Å; L312-A331 HydrophobicContact CD2-CB 4.1Å; L312-Y332 HydrophobicContact CB-CD2 4.34Å
313	L	89.6	Confident	80.4	Confident	1 Å²	1	45 Å²	45	1%	0.005	27%	0.268	C	S	.	.	H	α-helix	trans	-61.3	-50.7	173.9	-179	70.8	0	0	0	111.6	Y167 F255 S309 V311 L315 H316 Y317 Y332	Y167-L313 HydrophobicContact CE1-CD1 4.43Å; Y167-L313 HydrophobicContact CE1-CD2 4.03Å; F255-L313 HydrophobicContact CB-CD1 4.36Å; F255-L313 HydrophobicContact CB-CD2 4.28Å; F255-L313 HydrophobicContact CB-CG 4.12Å; F255-L313 HydrophobicContact CD1-CD1 3.79Å; F255-L313 HydrophobicContact CD1-CD2 3.83Å; F255-L313 HydrophobicContact CD1-CG 4.11Å; F255-L313 HydrophobicContact CD2-CD1 4.43Å; F255-L313 HydrophobicContact CE1-CD1 4.13Å; F255-L313 HydrophobicContact CG-CD1 3.95Å; F255-L313 HydrophobicContact CG-CD2 4.35Å; F255-L313 HydrophobicContact CG-CG 4.21Å; S309-L313 WeakPolarHBondContact O-CB 3.46Å; S309-L313 PolarHBondContact O-N 2.78Å; V311-L313 VanDerWaalsContact C-N 3.33Å; V311-L313 PolarHBondContact O-N 2.89Å; L313-L315 VanDerWaalsContact C-N 3.33Å; L313-L315 PolarHBondContact O-N 2.96Å; L313-H316 PolarHBondContact O-N 2.85Å; L313-Y317 HydrophobicContact CD1-CD2 3.78Å; L313-Y317 HydrophobicContact CD1-CE2 3.69Å; L313-Y317 HydrophobicContact CG-CD2 4.4Å; L313-Y317 WeakPolarHBondContact O-CD2 3.06Å; L313-Y317 PolarHBondContact O-N 2.8Å; L313-Y332 HydrophobicContact CB-CD2 4.36Å; L313-Y332 HydrophobicContact CB-CE2 4.02Å; L313-Y332 HydrophobicContact CD1-CE2 3.68Å; L313-Y332 HydrophobicContact CG-CE2 4.46Å
314	V	89.7	Confident	78.2	Confident	42 Å²	42	44.5 Å²	44.5	26%	0.255	27%	0.27	S	S	.	.	H	α-helix	trans	-63.9	-39.3	177.5	172.5	0	0	0	0	111.1	A259 N310 V311 S318	A259-V314 HydrophobicContact CB-CG2 3.37Å; N310-V314 WeakPolarHBondContact O-CG2 3.36Å; N310-V314 PolarHBondContact O-N 2.67Å; V311-V314 PolarHBondContact O-N 2.87Å; V314-S318 WeakPolarHBondContact O-CB 3.44Å; V314-S318 PolarHBondContact O-N 3.03Å; V314-S318 PolarHBondContact O-OG 3.47Å
315	L	86.1	Confident	76.1	Confident	45 Å²	45	48.3 Å²	48.3	24%	0.236	27%	0.27	C	S	.	.	H	α-helix	trans	-64.3	-44.7	175.3	-71.8	171.1	0	0	0	111.8	V311 L312 L313 Y317 S318 L328	V311-L315 HydrophobicContact CG1-CD1 3.86Å; V311-L315 HydrophobicContact CG1-CG 4.45Å; V311-L315 WeakPolarHBondContact O-CB 3.42Å; V311-L315 VanDerWaalsContact O-CG 3.3Å; V311-L315 WeakPolarHBondContact O-CG 3.27Å; V311-L315 PolarHBondContact O-N 2.95Å; L312-L315 PolarHBondContact O-N 2.69Å; L313-L315 VanDerWaalsContact C-N 3.33Å; L313-L315 PolarHBondContact O-N 2.96Å; L315-Y317 VanDerWaalsContact C-N 3.35Å; L315-Y317 PolarHBondContact O-N 3.36Å; L315-S318 PolarHBondContact O-N 3.13Å; L315-S318 PolarHBondContact O-OG 3.01Å; L315-L328 HydrophobicContact CB-CD1 3.89Å; L315-L328 HydrophobicContact CB-CD2 4.37Å
316	H	79.4	Confident	74.5	Confident	24 Å²	24	49.3 Å²	49.3	11%	0.111	28%	0.284	C	S	.	.	H	α-helix	trans	-63	-36.6	179.7	-175	97.9	0	0	0	113.1	L312 L313 L328	L312-H316 WeakPolarHBondContact O-CB 3.04Å; L312-H316 PolarHBondContact O-N 2.56Å; L313-H316 PolarHBondContact O-N 2.85Å; H316-L328 HydrophobicContact CB-CB 4.49Å
317	Y	79.1	Confident	73.1	Confident	15 Å²	15	52 Å²	52	6%	0.059	30%	0.298	C	S	.	.	H	α-helix	trans	-96.7	-3.3	177	-72.3	-78.4	0	0	0	114.2	L242 Q247 W251 R252 F255 L313 L315	L242-Y317 WeakPolarHBondContact CD1-OH 3.33Å; Q247-Y317 HydrophobicContact CG-CD1 4.24Å; W251-Y317 HydrophobicContact CB-CD1 3.84Å; W251-Y317 HydrophobicContact CB-CE1 3.7Å; W251-Y317 HydrophobicContact CG-CE1 4.36Å; R252-Y317 WeakPolarHBondContact CB-O 3.5Å; R252-Y317 VanDerWaalsContact CD-O 3.31Å; R252-Y317 WeakPolarHBondContact CD-O 3.24Å; R252-Y317 WeakPolarHBondContact CG-O 3.41Å; F255-Y317 HydrophobicContact CB-CD2 4.11Å; F255-Y317 HydrophobicContact CB-CG 4.35Å; F255-Y317 AromaticContact CD2-CD1 3.85Å; F255-Y317 HydrophobicContact CD2-CD1 3.85Å; F255-Y317 AromaticContact CD2-CD2 3.37Å; F255-Y317 HydrophobicContact CD2-CD2 3.37Å; F255-Y317 AromaticContact CD2-CE1 3.79Å; F255-Y317 HydrophobicContact CD2-CE1 3.79Å; F255-Y317 AromaticContact CD2-CE2 3.31Å; F255-Y317 HydrophobicContact CD2-CE2 3.31Å; F255-Y317 AromaticContact CD2-CG 3.65Å; F255-Y317 HydrophobicContact CD2-CG 3.65Å; F255-Y317 AromaticContact CD2-CZ 3.53Å; F255-Y317 HydrophobicContact CE2-CD1 4.33Å; F255-Y317 AromaticContact CE2-CD2 3.98Å; F255-Y317 HydrophobicContact CE2-CD2 3.98Å; F255-Y317 AromaticContact CE2-CE1 3.79Å; F255-Y317 HydrophobicContact CE2-CE1 3.79Å; F255-Y317 AromaticContact CE2-CE2 3.39Å; F255-Y317 HydrophobicContact CE2-CE2 3.39Å; F255-Y317 HydrophobicContact CE2-CG 4.42Å; F255-Y317 AromaticContact CE2-CZ 3.28Å; F255-Y317 WeakPolarHBondContact CE2-OH 3.37Å; F255-Y317 AromaticContact CG-CD2 3.9Å; F255-Y317 HydrophobicContact CG-CD2 3.9Å; F255-Y317 HydrophobicContact CG-CE2 4.07Å; F255-Y317 HydrophobicContact CG-CG 4.36Å; F255-Y317 HydrophobicContact CZ-CE2 4.2Å; L313-Y317 HydrophobicContact CD1-CD2 3.78Å; L313-Y317 HydrophobicContact CD1-CE2 3.69Å; L313-Y317 HydrophobicContact CG-CD2 4.4Å; L313-Y317 WeakPolarHBondContact O-CD2 3.06Å; L313-Y317 PolarHBondContact O-N 2.8Å; L315-Y317 VanDerWaalsContact C-N 3.35Å; L315-Y317 PolarHBondContact O-N 3.36Å
318	S	75	Confident	72.1	Confident	34 Å²	34	51.4 Å²	51.4	24%	0.238	29%	0.293	C	S	.	.	S	Bend	trans	-70.5	167.7	164	73.9	0	0	0	0	110	V314 L315 P320	V314-S318 WeakPolarHBondContact O-CB 3.44Å; V314-S318 PolarHBondContact O-N 3.03Å; V314-S318 PolarHBondContact O-OG 3.47Å; L315-S318 PolarHBondContact O-N 3.13Å; L315-S318 PolarHBondContact O-OG 3.01Å; S318-P320 WeakPolarHBondContact O-CD 3.26Å; S318-P320 WeakPolarHBondContact OG-CD 3.45Å
319	N	62.7	Low	71.2	Confident	125 Å²	125	49 Å²	49	67%	0.668	28%	0.277	S	S	*	.			trans	-111.8	61	-177.2	-165.4	13.8	0	0	0	111.8
320	P	52.4	Low	70.3	Confident	49 Å²	49	49.7 Å²	49.7	32%	0.318	29%	0.285	S	S	.	.			trans	-82.9	157	176.4	37.2	-34.2	0	0	0	110.7	S318 W325	S318-P320 WeakPolarHBondContact O-CD 3.26Å; S318-P320 WeakPolarHBondContact OG-CD 3.45Å; P320-W325 VanDerWaalsContact CB-CD1 3.46Å
321	S	47.2	Very low	69.9	Low	70 Å²	70	52 Å²	52	49%	0.49	30%	0.303	S	S	.	.			trans	-61.6	151.2	173.9	57	0	0	0	0	111.5	E323 A324	S321-E323 PolarHBondContact O-N 3.45Å; S321-A324 PolarHBondContact O-N 3.39Å
322	P	45.1	Very low	69.6	Low	41 Å²	41	49.7 Å²	49.7	27%	0.266	29%	0.288	S	S	.	.	T	Hydrogen-bonded Turn	trans	-54.6	-28.9	178.1	-27.4	35.2	0	0	0	113.6	R57 A324	R57-P322 PolarHBondContact NE-O 3.17Å; R57-P322 PolarHBondContact NH1-O 2.78Å; R57-P322 PolarHBondContact NH2-O 2.84Å; P322-A324 VanDerWaalsContact C-N 3.27Å; P322-A324 PolarHBondContact O-N 3.46Å
323	E	46	Very low	69.4	Low	160 Å²	160	48.5 Å²	48.5	75%	0.748	28%	0.282	S	S	*	.	T	Hydrogen-bonded Turn	trans	-69.5	-21.3	-175.5	-61.5	179.5	165.3	0	0	113.6	S321	S321-E323 PolarHBondContact O-N 3.45Å
324	A	48.5	Very low	69.4	Low	54 Å²	54	49.2 Å²	49.2	45%	0.446	29%	0.287	S	S	.	.	S	Bend	trans	-87.2	-33.1	-162.5	0	0	0	0	0	116.9	S321 P322	S321-A324 PolarHBondContact O-N 3.39Å; P322-A324 VanDerWaalsContact C-N 3.27Å; P322-A324 PolarHBondContact O-N 3.46Å
325	W	48.8	Very low	69.6	Low	148 Å²	148	47.9 Å²	47.9	56%	0.561	28%	0.279	S	S	*	.	S	Bend	trans	-136.1	14.1	-161.1	-60.4	107.5	0	0	0	118.3	P320 L328	P320-W325 VanDerWaalsContact CB-CD1 3.46Å; W325-L328 HydrophobicContact CB-CD1 3.97Å; W325-L328 HydrophobicContact CB-CD2 4.43Å; W325-L328 HydrophobicContact CB-CG 4.23Å
326	G	58.1	Low	69.9	Low	41 Å²	41	46.4 Å²	46.4	42%	0.423	27%	0.272	S	S	.	.			trans	68.8	-163.1	-177.3	0	0	0	0	0	113.2	R57	R57-G326 WeakPolarHBondContact CD-O 3.45Å; R57-G326 PolarHBondContact NH1-O 3.01Å
327	D	65.4	Low	70.6	Confident	56 Å²	56	45.3 Å²	45.3	30%	0.299	27%	0.267	S	S	.	.			trans	-94.6	97.4	168	-169.7	-14.4	0	0	0	109.6	L80 Y329 G330	L80-D327 HydrophobicContact CD2-CB 4.41Å; L80-D327 VanDerWaalsContact CD2-OD2 3.3Å; L80-D327 WeakPolarHBondContact CD2-OD2 3.5Å; D327-Y329 PolarHBondContact O-N 3.26Å; D327-Y329 WeakPolarHBondContact OD1-CB 3.46Å; D327-Y329 PolarHBondContact OD1-N 3.12Å; D327-G330 PolarHBondContact O-N 2.04Å
328	L	74.3	Confident	71.3	Confident	25 Å²	25	48.8 Å²	48.8	13%	0.131	29%	0.286	C	S	.	.	T	Hydrogen-bonded Turn	trans	-64.8	-21.6	-174.1	-73.9	162.6	0	0	0	113.5	L312 L315 H316 W325 G330 A331 Y332	L312-L328 HydrophobicContact CD2-CD2 3.84Å; L315-L328 HydrophobicContact CB-CD1 3.89Å; L315-L328 HydrophobicContact CB-CD2 4.37Å; H316-L328 HydrophobicContact CB-CB 4.49Å; W325-L328 HydrophobicContact CB-CD1 3.97Å; W325-L328 HydrophobicContact CB-CD2 4.43Å; W325-L328 HydrophobicContact CB-CG 4.23Å; L328-G330 VanDerWaalsContact C-N 3.31Å; L328-G330 PolarHBondContact O-N 2.86Å; L328-A331 PolarHBondContact O-N 2.97Å; L328-Y332 WeakPolarHBondContact O-CB 3.43Å; L328-Y332 PolarHBondContact O-N 3.26Å
329	Y	74.5	Confident	72.2	Confident	5 Å²	5	47.3 Å²	47.3	2%	0.02	28%	0.275	C	S	.	.	H	α-helix	trans	-59.9	-42.3	-178.8	-178.2	-89.5	0	0	0	111.9	F59 L80 P86 D240 D327 A331 Y332 V333	F59-Y329 HydrophobicContact CD2-CD1 4.45Å; F59-Y329 AromaticContact CD2-CD2 3.6Å; F59-Y329 HydrophobicContact CD2-CD2 3.6Å; F59-Y329 HydrophobicContact CD2-CE1 4.47Å; F59-Y329 AromaticContact CD2-CE2 3.6Å; F59-Y329 HydrophobicContact CD2-CE2 3.6Å; F59-Y329 HydrophobicContact CD2-CG 4.03Å; F59-Y329 AromaticContact CE2-CD1 3.64Å; F59-Y329 HydrophobicContact CE2-CD1 3.64Å; F59-Y329 AromaticContact CE2-CD2 3.6Å; F59-Y329 HydrophobicContact CE2-CD2 3.6Å; F59-Y329 AromaticContact CE2-CE1 3.59Å; F59-Y329 HydrophobicContact CE2-CE1 3.59Å; F59-Y329 AromaticContact CE2-CE2 3.54Å; F59-Y329 HydrophobicContact CE2-CE2 3.54Å; F59-Y329 AromaticContact CE2-CG 3.63Å; F59-Y329 HydrophobicContact CE2-CG 3.63Å; F59-Y329 AromaticContact CE2-CZ 3.53Å; F59-Y329 HydrophobicContact CZ-CE1 4.4Å; L80-Y329 HydrophobicContact CD2-CD1 3.9Å; L80-Y329 HydrophobicContact CG-CD1 4.02Å; P86-Y329 HydrophobicContact CG-CE1 4.26Å; D240-Y329 HydrophobicContact CB-CE2 4.4Å; D240-Y329 WeakPolarHBondContact CB-OH 3.41Å; D327-Y329 PolarHBondContact O-N 3.26Å; D327-Y329 WeakPolarHBondContact OD1-CB 3.46Å; D327-Y329 PolarHBondContact OD1-N 3.12Å; Y329-A331 PolarHBondContact O-N 3.41Å; Y329-Y332 PolarHBondContact O-N 2.6Å; Y329-V333 HydrophobicContact CD1-CG2 3.97Å; Y329-V333 HydrophobicContact CD2-CG2 3.91Å; Y329-V333 HydrophobicContact CE1-CG2 3.57Å; Y329-V333 HydrophobicContact CE2-CG2 3.51Å; Y329-V333 HydrophobicContact CG-CG2 4.14Å; Y329-V333 PolarHBondContact O-N 2.86Å
330	G	76.4	Confident	73.7	Confident	17 Å²	17	41.5 Å²	41.5	18%	0.175	25%	0.245	C	C	.	.	H	α-helix	trans	-65.7	-21.7	-177.3	0	0	0	0	0	114.1	D327 L328 P334	D327-G330 PolarHBondContact O-N 2.04Å; L328-G330 VanDerWaalsContact C-N 3.31Å; L328-G330 PolarHBondContact O-N 2.86Å; G330-P334 VanDerWaalsContact O-CD 3.26Å; G330-P334 WeakPolarHBondContact O-CD 3.44Å; G330-P334 WeakPolarHBondContact O-CG 3.31Å
331	A	84.9	Confident	75.6	Confident	47 Å²	47	41.1 Å²	41.1	39%	0.388	24%	0.239	S	C	.	.	H	α-helix	trans	-93.7	-39.5	171.3	0	0	0	0	0	112	L312 L328 Y329 P334 S335	L312-A331 HydrophobicContact CD1-CB 4.06Å; L312-A331 HydrophobicContact CD2-CB 4.1Å; L328-A331 PolarHBondContact O-N 2.97Å; Y329-A331 PolarHBondContact O-N 3.41Å; A331-P334 WeakPolarHBondContact O-CD 3.39Å; A331-P334 WeakPolarHBondContact O-CG 3.48Å; A331-S335 WeakPolarHBondContact O-CB 3.43Å; A331-S335 PolarHBondContact O-N 2.94Å
332	Y	87.1	Confident	77.7	Confident	13 Å²	13	37.8 Å²	37.8	5%	0.051	22%	0.216	C	C	.	.	H	α-helix	trans	-61.3	-51.4	-177	162.4	-108	0	0	0	112.8	Y167 L312 L313 L328 Y329 S335 L336	Y167-Y332 PolarHBondContact OH-OH 3.1Å; L312-Y332 HydrophobicContact CB-CD2 4.34Å; L313-Y332 HydrophobicContact CB-CD2 4.36Å; L313-Y332 HydrophobicContact CB-CE2 4.02Å; L313-Y332 HydrophobicContact CD1-CE2 3.68Å; L313-Y332 HydrophobicContact CG-CE2 4.46Å; L328-Y332 WeakPolarHBondContact O-CB 3.43Å; L328-Y332 PolarHBondContact O-N 3.26Å; Y329-Y332 PolarHBondContact O-N 2.6Å; Y332-S335 CarbonylContact O-C 3.56Å; Y332-S335 WeakPolarHBondContact O-CB 3.4Å; Y332-S335 PolarHBondContact O-N 3.49Å; Y332-S335 VanDerWaalsContact O-N 3.16Å; Y332-L336 HydrophobicContact CE2-CB 4.45Å; Y332-L336 PolarHBondContact O-N 3.49Å
333	V	87.3	Confident	80	Confident	7 Å²	7	35.9 Å²	35.9	4%	0.042	20%	0.204	C	C	.	.	H	α-helix	trans	-61.5	-50.8	-176.9	-175.9	0	0	0	0	113.1	V90 Y329 S335 L336 A337	V90-V333 HydrophobicContact CG2-CG1 3.73Å; Y329-V333 HydrophobicContact CD1-CG2 3.97Å; Y329-V333 HydrophobicContact CD2-CG2 3.91Å; Y329-V333 HydrophobicContact CE1-CG2 3.57Å; Y329-V333 HydrophobicContact CE2-CG2 3.51Å; Y329-V333 HydrophobicContact CG-CG2 4.14Å; Y329-V333 PolarHBondContact O-N 2.86Å; V333-S335 VanDerWaalsContact C-N 3.26Å; V333-S335 PolarHBondContact O-N 3.23Å; V333-L336 PolarHBondContact O-N 2.74Å; V333-A337 PolarHBondContact O-N 2.9Å
334	P	89.9	Confident	82.1	Confident	16 Å²	16	29.2 Å²	29.2	10%	0.104	18%	0.175	C	C	.	.	H	α-helix	trans	-65.7	-30.5	175.3	25.6	-32.9	0	0	0	111.9	I85 L89 G330 A331 A337 L338	I85-P334 HydrophobicContact CG2-CB 4.05Å; I85-P334 HydrophobicContact CG2-CG 3.8Å; L89-P334 HydrophobicContact CD2-CB 4.18Å; G330-P334 VanDerWaalsContact O-CD 3.26Å; G330-P334 WeakPolarHBondContact O-CD 3.44Å; G330-P334 WeakPolarHBondContact O-CG 3.31Å; A331-P334 WeakPolarHBondContact O-CD 3.39Å; A331-P334 WeakPolarHBondContact O-CG 3.48Å; P334-A337 PolarHBondContact O-N 3.5Å; P334-L338 WeakPolarHBondContact O-CB 3.14Å; P334-L338 WeakPolarHBondContact O-CG 3.19Å; P334-L338 PolarHBondContact O-N 2.78Å
335	S	93.4	Very high	84	Confident	13 Å²	13	28.7 Å²	28.7	9%	0.091	17%	0.166	C	C	.	.	H	α-helix	trans	-66.7	-37.5	173.6	-172.1	0	0	0	0	113	P308 S309 A331 Y332 V333 S339	P308-S335 WeakPolarHBondContact CB-OG 3.45Å; S309-S335 WeakPolarHBondContact CA-OG 3.19Å; S309-S335 PolarHBondContact N-OG 3.44Å; S309-S335 VanDerWaalsContact N-OG 3.09Å; A331-S335 WeakPolarHBondContact O-CB 3.43Å; A331-S335 PolarHBondContact O-N 2.94Å; Y332-S335 CarbonylContact O-C 3.56Å; Y332-S335 WeakPolarHBondContact O-CB 3.4Å; Y332-S335 PolarHBondContact O-N 3.49Å; Y332-S335 VanDerWaalsContact O-N 3.16Å; V333-S335 VanDerWaalsContact C-N 3.26Å; V333-S335 PolarHBondContact O-N 3.23Å; S335-S339 PolarHBondContact O-N 3.45Å
336	L	92.5	Very high	85.8	Confident	15 Å²	15	21.6 Å²	21.6	8%	0.079	14%	0.139	C	C	.	.	H	α-helix	trans	-64.8	-45.2	172.8	-178.4	66.2	0	0	0	110.2	L166 M170 Y332 V333 L338 S339 T340	L166-L336 HydrophobicContact CD2-CD2 4.09Å; M170-L336 HydrophobicContact SD-CD1 4.33Å; Y332-L336 HydrophobicContact CE2-CB 4.45Å; Y332-L336 PolarHBondContact O-N 3.49Å; V333-L336 PolarHBondContact O-N 2.74Å; L336-L338 PolarHBondContact O-N 3.44Å; L336-S339 WeakPolarHBondContact O-CB 3.39Å; L336-S339 PolarHBondContact O-N 3.06Å; L336-S339 VanDerWaalsContact O-N 3.13Å; L336-S339 PolarHBondContact O-OG 3.12Å; L336-T340 PolarHBondContact O-N 3.22Å
337	A	93.6	Very high	86.9	Confident	0 Å²	0	20.3 Å²	20.3	0%	0	12%	0.123	C	C	.	.	H	α-helix	trans	-60.7	-43.7	175.8	0	0	0	0	0	112.3	V90 L93 Y94 V333 P334 S339 T340	V90-A337 HydrophobicContact CB-CB 4.47Å; V90-A337 HydrophobicContact CG1-CB 4.11Å; V90-A337 HydrophobicContact CG2-CB 4.23Å; L93-A337 HydrophobicContact CB-CB 4.24Å; L93-A337 HydrophobicContact CD1-CB 3.74Å; Y94-A337 HydrophobicContact CE1-CB 3.91Å; V333-A337 PolarHBondContact O-N 2.9Å; P334-A337 PolarHBondContact O-N 3.5Å; A337-S339 VanDerWaalsContact C-N 3.29Å; A337-S339 PolarHBondContact O-N 3.01Å; A337-T340 WeakPolarHBondContact O-CB 3.45Å; A337-T340 PolarHBondContact O-N 3.05Å; A337-T340 PolarHBondContact O-OG1 3.45Å
338	L	94.1	Very high	87.3	Confident	88 Å²	88	23.1 Å²	23.1	46%	0.461	13%	0.133	S	C	.	.	H	α-helix	trans	-61.8	-34.6	174.2	-73.4	170	0	0	0	112.4	L93 P334 L336 T340 L341	L93-L338 HydrophobicContact CD1-CD2 4Å; L93-L338 HydrophobicContact CD1-CG 4.08Å; L93-L338 HydrophobicContact CD2-CD2 4.07Å; P334-L338 WeakPolarHBondContact O-CB 3.14Å; P334-L338 WeakPolarHBondContact O-CG 3.19Å; P334-L338 PolarHBondContact O-N 2.78Å; L336-L338 PolarHBondContact O-N 3.44Å; L338-T340 PolarHBondContact O-N 3.23Å; L338-L341 HydrophobicContact CD2-CD1 3.74Å; L338-L341 VanDerWaalsContact O-CB 3.3Å; L338-L341 WeakPolarHBondContact O-CB 3.48Å; L338-L341 PolarHBondContact O-N 3.28Å
339	S	94.9	Very high	87.4	Confident	3 Å²	3	22.1 Å²	22.1	2%	0.021	13%	0.128	C	C	.	.	H	α-helix	trans	-62	-30	177.1	79.1	0	0	0	0	113	S305 S335 L336 A337 L341 N342	S305-S339 WeakPolarHBondContact O-CA 3.46Å; S305-S339 WeakPolarHBondContact O-CB 3.48Å; S335-S339 PolarHBondContact O-N 3.45Å; L336-S339 WeakPolarHBondContact O-CB 3.39Å; L336-S339 PolarHBondContact O-N 3.06Å; L336-S339 VanDerWaalsContact O-N 3.13Å; L336-S339 PolarHBondContact O-OG 3.12Å; A337-S339 VanDerWaalsContact C-N 3.29Å; A337-S339 PolarHBondContact O-N 3.01Å; S339-L341 PolarHBondContact O-N 3.41Å; S339-N342 PolarHBondContact O-N 3.32Å
340	T	94.3	Very high	87.5	Confident	4 Å²	4	21.9 Å²	21.9	3%	0.025	13%	0.127	C	C	.	.	T	Hydrogen-bonded Turn	trans	-67.3	-19.7	175.6	70.5	0	0	0	0	113.3	Y94 L135 L166 L336 A337 L338 N342 S343	Y94-T340 HydrophobicContact CD1-CG2 4.49Å; Y94-T340 HydrophobicContact CE1-CG2 3.93Å; L135-T340 HydrophobicContact CD1-CG2 4.37Å; L135-T340 HydrophobicContact CD2-CG2 4.4Å; L166-T340 HydrophobicContact CD1-CG2 3.77Å; L336-T340 PolarHBondContact O-N 3.22Å; A337-T340 WeakPolarHBondContact O-CB 3.45Å; A337-T340 PolarHBondContact O-N 3.05Å; A337-T340 PolarHBondContact O-OG1 3.45Å; L338-T340 PolarHBondContact O-N 3.23Å; T340-N342 PolarHBondContact O-N 3.31Å; T340-S343 PolarHBondContact O-N 3.09Å; T340-S343 PolarHBondContact O-OG 3.01Å
341	L	92	Very high	87.2	Confident	40 Å²	40	24 Å²	24	21%	0.209	13%	0.13	C	C	.	.	T	Hydrogen-bonded Turn	trans	-67.8	-12.4	175.6	-64.4	172.2	0	0	0	113.6	L93 L96 V97 L338 S339 S343 C344 V345	L93-L341 HydrophobicContact CD2-CD1 4.19Å; L96-L341 HydrophobicContact CD2-CD2 3.91Å; L96-L341 HydrophobicContact CG-CD2 4.38Å; V97-L341 HydrophobicContact CG2-CD2 3.72Å; V97-L341 HydrophobicContact CG2-CG 4.43Å; L338-L341 HydrophobicContact CD2-CD1 3.74Å; L338-L341 VanDerWaalsContact O-CB 3.3Å; L338-L341 WeakPolarHBondContact O-CB 3.48Å; L338-L341 PolarHBondContact O-N 3.28Å; S339-L341 PolarHBondContact O-N 3.41Å; L341-S343 PolarHBondContact O-N 2.99Å; L341-C344 WeakPolarHBondContact O-CB 3.48Å; L341-C344 PolarHBondContact O-N 3.21Å; L341-V345 PolarHBondContact O-N 2.84Å
342	N	91.8	Very high	86.4	Confident	0 Å²	0	25 Å²	25	0%	0	12%	0.124	C	C	.	.	H	α-helix	trans	-56.7	-35.9	174.6	-168.8	90.4	0	0	0	111.3	S301 F306 S339 T340 C344 V345 D346	S301-N342 PolarHBondContact OG-OD1 3.18Å; F306-N342 HydrophobicContact CE1-CB 4.12Å; F306-N342 HydrophobicContact CE2-CB 4.19Å; F306-N342 HydrophobicContact CZ-CB 3.57Å; S339-N342 PolarHBondContact O-N 3.32Å; T340-N342 PolarHBondContact O-N 3.31Å; N342-C344 PolarHBondContact O-N 3.13Å; N342-C344 VanDerWaalsContact O-N 3.09Å; N342-V345 WeakPolarHBondContact O-CA 3.2Å; N342-V345 WeakPolarHBondContact O-CB 3.23Å; N342-V345 PolarHBondContact O-N 3Å; N342-D346 VanDerWaalsContact ND2-CG 3.31Å; N342-D346 PolarHBondContact ND2-OD1 3.24Å; N342-D346 VanDerWaalsContact ND2-OD1 3.11Å; N342-D346 PolarHBondContact ND2-OD2 2.89Å; N342-D346 PolarHBondContact O-N 3.46Å; N342-D346 VanDerWaalsContact O-OD2 3.04Å
343	S	93	Very high	85.5	Confident	1 Å²	1	27.4 Å²	27.4	1%	0.007	14%	0.14	C	C	.	.	H	α-helix	trans	-63.8	-15.7	177	69.6	0	0	0	0	113.8	V97 N105 D132 T340 L341 D346 P347	V97-S343 WeakPolarHBondContact CG1-OG 3.33Å; N105-S343 PolarHBondContact ND2-O 3.37Å; D132-S343 WeakPolarHBondContact OD1-CB 3.39Å; T340-S343 PolarHBondContact O-N 3.09Å; T340-S343 PolarHBondContact O-OG 3.01Å; L341-S343 PolarHBondContact O-N 2.99Å; S343-D346 WeakPolarHBondContact CA-OD2 3.34Å; S343-P347 VanDerWaalsContact O-CD 3.24Å; S343-P347 WeakPolarHBondContact O-CD 3.29Å
344	C	89.8	Confident	84.4	Confident	20 Å²	20	27.3 Å²	27.3	14%	0.135	14%	0.139	C	C	.	.	H	α-helix	trans	-89.8	-17.2	170.7	-61.9	0	0	0	0	112.7	V100 L341 N342	V100-C344 HydrophobicContact CG1-CB 4.4Å; L341-C344 WeakPolarHBondContact O-CB 3.48Å; L341-C344 PolarHBondContact O-N 3.21Å; N342-C344 PolarHBondContact O-N 3.13Å; N342-C344 VanDerWaalsContact O-N 3.09Å
345	V	88.1	Confident	83.4	Confident	43 Å²	43	31.5 Å²	31.5	26%	0.261	16%	0.157	S	C	.	.	H	α-helix	trans	-84.4	-33.7	173.1	-174.7	0	0	0	0	111.2	L341 N342 P347 F348	L341-V345 PolarHBondContact O-N 2.84Å; N342-V345 WeakPolarHBondContact O-CA 3.2Å; N342-V345 WeakPolarHBondContact O-CB 3.23Å; N342-V345 PolarHBondContact O-N 3Å; V345-P347 VanDerWaalsContact C-N 3.33Å; V345-F348 WeakPolarHBondContact O-CB 3.46Å; V345-F348 WeakPolarHBondContact O-CD2 3.34Å; V345-F348 PolarHBondContact O-N 3.34Å
346	D	87.1	Confident	82.4	Confident	0 Å²	0	34.5 Å²	34.5	0%	0	17%	0.17	C	C	.	.	H	α-helix	trans	-55.5	-36.5	-179.6	-63	-43.6	0	0	0	114.1	L128 N342 S343 F348 I349 Y350	L128-D346 HydrophobicContact CD2-CB 4.05Å; L128-D346 HydrophobicContact CG-CB 4.4Å; N342-D346 VanDerWaalsContact ND2-CG 3.31Å; N342-D346 PolarHBondContact ND2-OD1 3.24Å; N342-D346 VanDerWaalsContact ND2-OD1 3.11Å; N342-D346 PolarHBondContact ND2-OD2 2.89Å; N342-D346 PolarHBondContact O-N 3.46Å; N342-D346 VanDerWaalsContact O-OD2 3.04Å; S343-D346 WeakPolarHBondContact CA-OD2 3.34Å; D346-F348 PolarHBondContact O-N 2.95Å; D346-F348 VanDerWaalsContact O-N 3.16Å; D346-I349 HydrophobicContact CB-CD1 4.31Å; D346-I349 WeakPolarHBondContact O-CA 3.17Å; D346-I349 WeakPolarHBondContact O-CB 3.48Å; D346-I349 PolarHBondContact O-N 3.46Å; D346-I349 VanDerWaalsContact OD1-CD1 3.24Å; D346-I349 WeakPolarHBondContact OD1-CD1 3.41Å; D346-Y350 HydrophobicContact CB-CE2 4.37Å; D346-Y350 WeakPolarHBondContact O-CD2 3.42Å; D346-Y350 WeakPolarHBondContact O-CE2 3.45Å; D346-Y350 PolarHBondContact O-N 2.96Å
347	P	80.8	Confident	81.2	Confident	13 Å²	13	34.2 Å²	34.2	8%	0.084	17%	0.168	C	C	.	.	H	α-helix	trans	-50.2	-31.8	166.4	-33.7	38.1	0	0	0	117.1	A104 S343 V345 Y350 Y351	A104-P347 HydrophobicContact CB-CB 3.95Å; A104-P347 HydrophobicContact CB-CG 3.54Å; S343-P347 VanDerWaalsContact O-CD 3.24Å; S343-P347 WeakPolarHBondContact O-CD 3.29Å; V345-P347 VanDerWaalsContact C-N 3.33Å; P347-Y350 PolarHBondContact O-N 3.4Å; P347-Y351 PolarHBondContact O-N 2.69Å
348	F	73.9	Confident	80.5	Confident	116 Å²	116	37.9 Å²	37.9	51%	0.509	18%	0.182	S	C	.	.	H	α-helix	trans	-72.6	-33	175.1	-64.9	-92.9	0	0	0	111.4	V345 D346 Y350 Y351 Y352	V345-F348 WeakPolarHBondContact O-CB 3.46Å; V345-F348 WeakPolarHBondContact O-CD2 3.34Å; V345-F348 PolarHBondContact O-N 3.34Å; D346-F348 PolarHBondContact O-N 2.95Å; D346-F348 VanDerWaalsContact O-N 3.16Å; F348-Y350 VanDerWaalsContact C-N 3.31Å; F348-Y350 PolarHBondContact O-N 3.23Å; F348-Y351 PolarHBondContact O-N 3.17Å; F348-Y352 WeakPolarHBondContact O-CD2 3.26Å; F348-Y352 PolarHBondContact O-N 2.91Å
349	I	77.1	Confident	79.8	Confident	4 Å²	4	37.2 Å²	37.2	2%	0.021	18%	0.179	C	C	.	.	H	α-helix	trans	-58.9	-46.8	172.2	-50.7	172	0	0	0	109.1	L125 L128 L177 L294 V298 D346 Y351 Y352 V353	L125-I349 HydrophobicContact CD2-CG2 3.9Å; L128-I349 HydrophobicContact CD2-CD1 4.36Å; L177-I349 HydrophobicContact CD2-CD1 3.99Å; L294-I349 HydrophobicContact CD1-CG2 4.07Å; V298-I349 HydrophobicContact CG2-CD1 3.72Å; V298-I349 HydrophobicContact CG2-CG1 3.91Å; V298-I349 HydrophobicContact CG2-CG2 4.28Å; D346-I349 HydrophobicContact CB-CD1 4.31Å; D346-I349 WeakPolarHBondContact O-CA 3.17Å; D346-I349 WeakPolarHBondContact O-CB 3.48Å; D346-I349 PolarHBondContact O-N 3.46Å; D346-I349 VanDerWaalsContact OD1-CD1 3.24Å; D346-I349 WeakPolarHBondContact OD1-CD1 3.41Å; I349-Y351 VanDerWaalsContact C-N 3.35Å; I349-Y351 PolarHBondContact O-N 2.94Å; I349-Y352 PolarHBondContact O-N 3.12Å; I349-V353 HydrophobicContact CG2-CG2 4.48Å; I349-V353 WeakPolarHBondContact O-CB 3.27Å; I349-V353 VanDerWaalsContact O-CG2 3.22Å; I349-V353 WeakPolarHBondContact O-CG2 3.38Å; I349-V353 PolarHBondContact O-N 2.87Å; I349-V353 VanDerWaalsContact O-N 3.12Å
350	Y	74.9	Confident	78.9	Confident	0 Å²	0	40.4 Å²	40.4	0%	0	19%	0.192	C	C	.	.	H	α-helix	trans	-64.3	-39.1	178	-44.6	-43.2	0	0	0	111.9	N105 A108 L112 L125 L128 A129 D346 P347 F348 V353 S354	N105-Y350 WeakPolarHBondContact OD1-CE2 3.26Å; A108-Y350 HydrophobicContact CB-CD2 3.22Å; A108-Y350 HydrophobicContact CB-CE2 3.7Å; A108-Y350 HydrophobicContact CB-CG 3.98Å; L112-Y350 HydrophobicContact CD1-CD1 4.13Å; L112-Y350 HydrophobicContact CD1-CE1 4.42Å; L112-Y350 HydrophobicContact CD1-CG 4.45Å; L125-Y350 HydrophobicContact CB-CD1 3.93Å; L125-Y350 HydrophobicContact CB-CE1 3.73Å; L125-Y350 HydrophobicContact CD1-CD1 4.31Å; L125-Y350 HydrophobicContact CD2-CD1 3.86Å; L125-Y350 HydrophobicContact CD2-CE1 3.69Å; L125-Y350 HydrophobicContact CG-CD1 4.23Å; L125-Y350 HydrophobicContact CG-CE1 4.21Å; L128-Y350 HydrophobicContact CD2-CE1 4.38Å; L128-Y350 WeakPolarHBondContact CG-OH 3.34Å; A129-Y350 HydrophobicContact CB-CE2 4.27Å; A129-Y350 PolarHBondContact N-OH 3.31Å; D346-Y350 HydrophobicContact CB-CE2 4.37Å; D346-Y350 WeakPolarHBondContact O-CD2 3.42Å; D346-Y350 WeakPolarHBondContact O-CE2 3.45Å; D346-Y350 PolarHBondContact O-N 2.96Å; P347-Y350 PolarHBondContact O-N 3.4Å; F348-Y350 VanDerWaalsContact C-N 3.31Å; F348-Y350 PolarHBondContact O-N 3.23Å; Y350-V353 PolarHBondContact O-N 2.82Å; Y350-S354 PolarHBondContact O-N 3.33Å
351	Y	71.6	Confident	78	Confident	61 Å²	61	41.6 Å²	41.6	24%	0.239	20%	0.199	C	C	.	.	H	α-helix	trans	-60.5	-43.6	175.4	-174.4	-88.1	0	0	0	113.3	P347 F348 I349 V353 F357 R358 V361	P347-Y351 PolarHBondContact O-N 2.69Å; F348-Y351 PolarHBondContact O-N 3.17Å; I349-Y351 VanDerWaalsContact C-N 3.35Å; I349-Y351 PolarHBondContact O-N 2.94Å; Y351-V353 VanDerWaalsContact C-N 3.32Å; Y351-V353 PolarHBondContact O-N 2.74Å; Y351-F357 HydrophobicContact CD2-CD1 4.32Å; Y351-F357 HydrophobicContact CD2-CE1 4.45Å; Y351-R358 HydrophobicContact CD1-CG 4.1Å; Y351-R358 HydrophobicContact CD2-CB 4.23Å; Y351-R358 HydrophobicContact CD2-CG 3.74Å; Y351-R358 HydrophobicContact CE1-CG 4.03Å; Y351-R358 HydrophobicContact CE2-CB 3.85Å; Y351-R358 HydrophobicContact CE2-CG 3.67Å; Y351-R358 HydrophobicContact CG-CG 3.94Å; Y351-R358 WeakPolarHBondContact O-CD 3.49Å; Y351-R358 WeakPolarHBondContact O-CG 3.33Å; Y351-V361 HydrophobicContact CD2-CB 4.48Å; Y351-V361 HydrophobicContact CD2-CG1 4.44Å; Y351-V361 HydrophobicContact CE2-CB 4.49Å; Y351-V361 HydrophobicContact CE2-CG1 4.32Å
352	Y	67.9	Low	77.5	Confident	69 Å²	69	45.1 Å²	45.1	27%	0.271	21%	0.21	S	C	.	.	H	α-helix	trans	-77.2	-16.5	177	-69.9	-69.7	0	0	0	113.5	H290 F348 I349 L394	H290-Y352 PolarHBondContact CE1-O 3.45Å; H290-Y352 AromaticContact NE2-CD1 3.93Å; F348-Y352 WeakPolarHBondContact O-CD2 3.26Å; F348-Y352 PolarHBondContact O-N 2.91Å; I349-Y352 PolarHBondContact O-N 3.12Å; Y352-L394 PolarHBondContact OH-O 3.08Å; Y352-L394 VanDerWaalsContact OH-O 3.04Å
353	V	67.7	Low	76.9	Confident	62 Å²	62	48 Å²	48	38%	0.376	23%	0.234	S	C	.	.	H	α-helix	trans	-95.4	-38.3	-178	174	0	0	0	0	114.2	L125 L294 I349 Y350 Y351	L125-V353 HydrophobicContact CD1-CB 4.3Å; L125-V353 HydrophobicContact CD1-CG1 3.84Å; L294-V353 HydrophobicContact CD1-CG2 4.47Å; L294-V353 HydrophobicContact CD2-CG2 3.42Å; L294-V353 VanDerWaalsContact CD2-CG2 3.42Å; I349-V353 HydrophobicContact CG2-CG2 4.48Å; I349-V353 WeakPolarHBondContact O-CB 3.27Å; I349-V353 VanDerWaalsContact O-CG2 3.22Å; I349-V353 WeakPolarHBondContact O-CG2 3.38Å; I349-V353 PolarHBondContact O-N 2.87Å; I349-V353 VanDerWaalsContact O-N 3.12Å; Y350-V353 PolarHBondContact O-N 2.82Å; Y351-V353 VanDerWaalsContact C-N 3.32Å; Y351-V353 PolarHBondContact O-N 2.74Å
354	S	64.7	Low	76.2	Confident	5 Å²	5	52.9 Å²	52.9	4%	0.035	26%	0.259	C	S	.	.			trans	-113.4	121.4	-175.6	166.5	0	0	0	0	111.9	V116 Y350 E356 F357 R358	V116-S354 WeakPolarHBondContact CG2-OG 3.19Å; Y350-S354 PolarHBondContact O-N 3.33Å; S354-E356 VanDerWaalsContact C-N 3.29Å; S354-E356 PolarHBondContact O-N 3.32Å; S354-E356 PolarHBondContact OG-N 2.59Å; S354-E356 PolarHBondContact OG-OE2 3.39Å; S354-F357 PolarHBondContact O-N 3.45Å; S354-F357 PolarHBondContact OG-N 2.83Å; S354-F357 VanDerWaalsContact OG-N 3.07Å; S354-R358 WeakPolarHBondContact O-CG 3.28Å; S354-R358 PolarHBondContact O-N 3.32Å
355	H	69.1	Low	75.6	Confident	104 Å²	104	58.6 Å²	58.6	48%	0.481	29%	0.287	S	S	.	.	H	α-helix	trans	-66.4	-36.6	175	-150.2	-72.1	0	0	0	111.2	F357 R358 D359	H355-F357 VanDerWaalsContact C-N 3.3Å; H355-F357 PolarHBondContact O-N 3.21Å; H355-R358 WeakPolarHBondContact O-CB 3.42Å; H355-R358 PolarHBondContact O-N 2.96Å; H355-R358 VanDerWaalsContact O-N 3.12Å; H355-D359 IonicContact CE1-OD1 3.79Å; H355-D359 IonicContact CE1-OD2 2.74Å; H355-D359 IonicContact CG-OD2 2.73Å; H355-D359 IonicContact ND1-OD1 3.21Å; H355-D359 IonicContact ND1-OD2 2.81Å; H355-D359 PolarHBondContact ND1-OD2 2.84Å; H355-D359 VanDerWaalsContact O-CG 3.24Å; H355-D359 PolarHBondContact O-N 3.44Å; H355-D359 VanDerWaalsContact O-OD2 3.12Å
356	E	72.8	Confident	75	Confident	77 Å²	77	60.3 Å²	60.3	36%	0.36	30%	0.3	S	S	.	.	H	α-helix	trans	-62.2	-37.3	178.4	-52.2	74.2	-164.2	0	0	111.7	V111 R115 S354 K360	V111-E356 HydrophobicContact CG1-CB 4.13Å; R115-E356 HydrophobicContact CB-CB 4.21Å; R115-E356 HydrophobicContact CB-CG 4.44Å; S354-E356 VanDerWaalsContact C-N 3.29Å; S354-E356 PolarHBondContact O-N 3.32Å; S354-E356 PolarHBondContact OG-N 2.59Å; S354-E356 PolarHBondContact OG-OE2 3.39Å; E356-K360 WeakPolarHBondContact O-CG 3.42Å; E356-K360 PolarHBondContact O-N 2.86Å; E356-K360 VanDerWaalsContact O-N 3.08Å
357	F	67.1	Low	73.5	Confident	9 Å²	9	69.6 Å²	69.6	4%	0.039	34%	0.335	C	S	.	.	H	α-helix	trans	-69	-43.5	173.1	-175.2	-94.9	0	0	0	111.3	L107 A108 V111 Y351 S354 H355 D359 K360 V361	L107-F357 HydrophobicContact CB-CE2 4.41Å; L107-F357 HydrophobicContact CD2-CE2 4.1Å; L107-F357 HydrophobicContact CG-CE2 3.96Å; A108-F357 VanDerWaalsContact CA-CE2 3.47Å; A108-F357 HydrophobicContact CB-CD2 4.28Å; A108-F357 HydrophobicContact CB-CE2 3.69Å; A108-F357 HydrophobicContact CB-CZ 4.27Å; V111-F357 HydrophobicContact CB-CD2 4.17Å; V111-F357 HydrophobicContact CG1-CB 4.01Å; V111-F357 HydrophobicContact CG1-CD2 4.47Å; V111-F357 HydrophobicContact CG2-CD2 4.14Å; Y351-F357 HydrophobicContact CD2-CD1 4.32Å; Y351-F357 HydrophobicContact CD2-CE1 4.45Å; S354-F357 PolarHBondContact O-N 3.45Å; S354-F357 PolarHBondContact OG-N 2.83Å; S354-F357 VanDerWaalsContact OG-N 3.07Å; H355-F357 VanDerWaalsContact C-N 3.3Å; H355-F357 PolarHBondContact O-N 3.21Å; F357-D359 VanDerWaalsContact C-N 3.29Å; F357-D359 PolarHBondContact O-N 3.13Å; F357-K360 PolarHBondContact O-N 3.41Å; F357-V361 HydrophobicContact CD1-CG2 3.89Å; F357-V361 HydrophobicContact CE1-CG2 3.54Å; F357-V361 HydrophobicContact CE2-CG2 4.25Å; F357-V361 HydrophobicContact CG-CG2 4.46Å; F357-V361 HydrophobicContact CZ-CG2 3.74Å; F357-V361 WeakPolarHBondContact O-CB 3.41Å; F357-V361 WeakPolarHBondContact O-CG2 3.31Å; F357-V361 PolarHBondContact O-N 3.42Å
358	R	78.4	Confident	72	Confident	77 Å²	77	76.6 Å²	76.6	29%	0.291	37%	0.367	S	S	.	.	H	α-helix	trans	-57.3	-43.1	174.6	-61.9	174.5	72	-158.8	3.4	111.8	Y351 S354 H355 V361 R362	Y351-R358 HydrophobicContact CD1-CG 4.1Å; Y351-R358 HydrophobicContact CD2-CB 4.23Å; Y351-R358 HydrophobicContact CD2-CG 3.74Å; Y351-R358 HydrophobicContact CE1-CG 4.03Å; Y351-R358 HydrophobicContact CE2-CB 3.85Å; Y351-R358 HydrophobicContact CE2-CG 3.67Å; Y351-R358 HydrophobicContact CG-CG 3.94Å; Y351-R358 WeakPolarHBondContact O-CD 3.49Å; Y351-R358 WeakPolarHBondContact O-CG 3.33Å; S354-R358 WeakPolarHBondContact O-CG 3.28Å; S354-R358 PolarHBondContact O-N 3.32Å; H355-R358 WeakPolarHBondContact O-CB 3.42Å; H355-R358 PolarHBondContact O-N 2.96Å; H355-R358 VanDerWaalsContact O-N 3.12Å; R358-V361 PolarHBondContact O-N 2.76Å; R358-R362 VanDerWaalsContact O-CB 3.24Å; R358-R362 WeakPolarHBondContact O-CB 3.38Å; R358-R362 PolarHBondContact O-N 2.77Å
359	D	78.4	Confident	70.5	Confident	74 Å²	74	76.5 Å²	76.5	40%	0.396	38%	0.378	S	S	.	.	H	α-helix	trans	-70.8	-34.3	-178.5	-63.9	-32.2	0	0	0	111.6	H355 F357 A363	H355-D359 IonicContact CE1-OD1 3.79Å; H355-D359 IonicContact CE1-OD2 2.74Å; H355-D359 IonicContact CG-OD2 2.73Å; H355-D359 IonicContact ND1-OD1 3.21Å; H355-D359 IonicContact ND1-OD2 2.81Å; H355-D359 PolarHBondContact ND1-OD2 2.84Å; H355-D359 VanDerWaalsContact O-CG 3.24Å; H355-D359 PolarHBondContact O-N 3.44Å; H355-D359 VanDerWaalsContact O-OD2 3.12Å; F357-D359 VanDerWaalsContact C-N 3.29Å; F357-D359 PolarHBondContact O-N 3.13Å; D359-A363 VanDerWaalsContact O-CB 3.29Å; D359-A363 WeakPolarHBondContact O-CB 3.42Å; D359-A363 PolarHBondContact O-N 3.33Å
360	K	76.2	Confident	68.7	Low	69 Å²	69	82.5 Å²	82.5	30%	0.3	41%	0.41	S	S	.	.	H	α-helix	trans	-69.3	-44.4	171.3	-76.1	-63.6	-176	-173.2	0	113.3	W110 V111 E356 F357 R362 A363 I364	W110-K360 HydrophobicContact CZ3-CD 4.3Å; W110-K360 HydrophobicContact CZ3-CG 4.44Å; V111-K360 HydrophobicContact CG2-CB 4.37Å; V111-K360 HydrophobicContact CG2-CG 4.17Å; E356-K360 WeakPolarHBondContact O-CG 3.42Å; E356-K360 PolarHBondContact O-N 2.86Å; E356-K360 VanDerWaalsContact O-N 3.08Å; F357-K360 PolarHBondContact O-N 3.41Å; K360-R362 VanDerWaalsContact C-N 3.34Å; K360-A363 PolarHBondContact O-N 3.06Å; K360-I364 WeakPolarHBondContact O-CG1 3.47Å; K360-I364 PolarHBondContact O-N 2.72Å; K360-I364 VanDerWaalsContact O-N 3.07Å
361	V	75.8	Confident	66.8	Low	29 Å²	29	89.2 Å²	89.2	18%	0.176	45%	0.451	C	S	.	.	H	α-helix	trans	-61.7	-43.6	174.1	169.8	0	0	0	0	110.4	L107 Y351 F357 R358 A363 I364 L365	L107-V361 HydrophobicContact CD2-CG2 4.07Å; Y351-V361 HydrophobicContact CD2-CB 4.48Å; Y351-V361 HydrophobicContact CD2-CG1 4.44Å; Y351-V361 HydrophobicContact CE2-CB 4.49Å; Y351-V361 HydrophobicContact CE2-CG1 4.32Å; F357-V361 HydrophobicContact CD1-CG2 3.89Å; F357-V361 HydrophobicContact CE1-CG2 3.54Å; F357-V361 HydrophobicContact CE2-CG2 4.25Å; F357-V361 HydrophobicContact CG-CG2 4.46Å; F357-V361 HydrophobicContact CZ-CG2 3.74Å; F357-V361 WeakPolarHBondContact O-CB 3.41Å; F357-V361 WeakPolarHBondContact O-CG2 3.31Å; F357-V361 PolarHBondContact O-N 3.42Å; R358-V361 PolarHBondContact O-N 2.76Å; V361-A363 PolarHBondContact O-N 3.43Å; V361-I364 PolarHBondContact O-N 2.97Å; V361-L365 HydrophobicContact CG1-CD1 3.58Å; V361-L365 HydrophobicContact CG1-CG 4.19Å; V361-L365 WeakPolarHBondContact O-CB 3.39Å; V361-L365 WeakPolarHBondContact O-CG 3.44Å; V361-L365 PolarHBondContact O-N 3.49Å
362	R	80.5	Confident	65.3	Low	114 Å²	114	91.6 Å²	91.6	43%	0.43	48%	0.477	S	S	.	.	H	α-helix	trans	-61.5	-43	174.3	-169.9	-170.9	-62.9	-114.4	1.4	111.8	R358 K360 I364 L365 C366	R358-R362 VanDerWaalsContact O-CB 3.24Å; R358-R362 WeakPolarHBondContact O-CB 3.38Å; R358-R362 PolarHBondContact O-N 2.77Å; K360-R362 VanDerWaalsContact C-N 3.34Å; R362-I364 PolarHBondContact O-N 3.25Å; R362-L365 PolarHBondContact O-N 3.41Å; R362-C366 HydrophobicContact CG-CB 4.29Å; R362-C366 WeakPolarHBondContact O-CA 3.4Å; R362-C366 WeakPolarHBondContact O-CB 3.27Å; R362-C366 PolarHBondContact O-N 3.2Å
363	A	80.3	Confident	63.7	Low	60 Å²	60	93 Å²	93	50%	0.496	50%	0.497	S	S	.	.	H	α-helix	trans	-65.7	-25.6	177.5	0	0	0	0	0	113.6	D359 K360 V361 R367	D359-A363 VanDerWaalsContact O-CB 3.29Å; D359-A363 WeakPolarHBondContact O-CB 3.42Å; D359-A363 PolarHBondContact O-N 3.33Å; K360-A363 PolarHBondContact O-N 3.06Å; V361-A363 PolarHBondContact O-N 3.43Å; A363-R367 WeakPolarHBondContact O-CB 3.42Å
364	I	78.9	Confident	62.2	Low	105 Å²	105	95.4 Å²	95.4	54%	0.538	52%	0.516	S	S	.	.	H	α-helix	trans	-81.4	-48.6	174.6	-66.8	163.8	0	0	0	110.6	L107 K360 V361 R362	L107-I364 HydrophobicContact CD1-CD1 4.29Å; L107-I364 HydrophobicContact CD2-CD1 3.81Å; K360-I364 WeakPolarHBondContact O-CG1 3.47Å; K360-I364 PolarHBondContact O-N 2.72Å; K360-I364 VanDerWaalsContact O-N 3.07Å; V361-I364 PolarHBondContact O-N 2.97Å; R362-I364 PolarHBondContact O-N 3.25Å
365	L	76	Confident	60.6	Low	139 Å²	139	100.9 Å²	100.9	73%	0.728	56%	0.555	S	S	*	*	H	α-helix	trans	-75.1	-33.7	-176.7	-66.3	177.2	0	0	0	113.7	V361 R362	V361-L365 HydrophobicContact CG1-CD1 3.58Å; V361-L365 HydrophobicContact CG1-CG 4.19Å; V361-L365 WeakPolarHBondContact O-CB 3.39Å; V361-L365 WeakPolarHBondContact O-CG 3.44Å; V361-L365 PolarHBondContact O-N 3.49Å; R362-L365 PolarHBondContact O-N 3.41Å
366	C	76.4	Confident	59.2	Low	80 Å²	80	105.1 Å²	105.1	54%	0.541	58%	0.575	S	S	.	*	T	Hydrogen-bonded Turn	trans	-100.7	23.2	-179.8	-52.4	0	0	0	0	112.2	R362 Q368	R362-C366 HydrophobicContact CG-CB 4.29Å; R362-C366 WeakPolarHBondContact O-CA 3.4Å; R362-C366 WeakPolarHBondContact O-CB 3.27Å; R362-C366 PolarHBondContact O-N 3.2Å; C366-Q368 PolarHBondContact O-N 3.45Å
367	R	55.6	Low	57.2	Low	194 Å²	194	106.1 Å²	106.1	73%	0.732	60%	0.596	S	S	*	*			trans	-68.6	94.5	176.1	-163.1	173.6	-175.6	171.2	0.8	109.4	A363	A363-R367 WeakPolarHBondContact O-CB 3.42Å
368	Q	48.3	Very low	55.5	Low	160 Å²	160	114.1 Å²	114.1	75%	0.748	63%	0.631	S	S	*	*			trans	-59.5	147.5	165.4	-69.2	-169	-58.5	0	0	109.1	C366 D370	C366-Q368 PolarHBondContact O-N 3.45Å; Q368-D370 PolarHBondContact O-N 2.9Å
369	P	41.8	Very low	53.3	Low	114 Å²	114	119.8 Å²	119.8	74%	0.74	65%	0.652	S	S	*	*			trans	-63.5	119.6	166.2	27.3	-32.3	0	0	0	108.5	T371	P369-T371 PolarHBondContact O-N 2.96Å
370	D	40.4	Very low	51.2	Low	131 Å²	131	124.5 Å²	124.5	70%	0.701	67%	0.672	S	S	*	*			trans	-64.1	97.6	174.2	-70.2	-56.3	0	0	0	109.4	Q368 S372	Q368-D370 PolarHBondContact O-N 2.9Å; D370-S372 PolarHBondContact O-N 3.41Å
371	T	35.1	Very low	49	Very low	140 Å²	140	127.9 Å²	127.9	86%	0.859	70%	0.698	S	S	*	*			trans	-75.3	72.5	170.5	46.1	0	0	0	0	110.2	P369 S373	P369-T371 PolarHBondContact O-N 2.96Å; T371-S373 PolarHBondContact O-N 2.98Å
372	S	40.6	Very low	46.9	Very low	111 Å²	111	130.1 Å²	130.1	78%	0.776	73%	0.727	S	S	*	*			trans	-89.2	85.9	176.3	63.9	0	0	0	0	111.9	D370	D370-S372 PolarHBondContact O-N 3.41Å
373	S	33.9	Very low	44.5	Very low	100 Å²	100	130.7 Å²	130.7	70%	0.699	75%	0.749	S	S	*	*			trans	-152.6	95.3	157.5	63.1	0	0	0	0	112.5	T371	T371-S373 PolarHBondContact O-N 2.98Å
374	S	35.7	Very low	42.6	Very low	111 Å²	111	139.3 Å²	139.3	78%	0.776	77%	0.768	S	S	*	*			trans	33.6	114.3	140.9	55.9	0	0	0	0	120
375	S	32.3	Very low	40.2	Very low	121 Å²	121	137.7 Å²	137.7	85%	0.846	78%	0.777	S	S	*	*				-173.8	148.6	104.2	-78.4	0	0	0	0	112.3
376	Q	37.9	Very low	38.2	Very low	193 Å²	193	136.7 Å²	136.7	90%	0.902	78%	0.778	S	S	*	*			trans	-75.5	136.4	168.6	-65	171.7	-22.4	0	0	109.9
377	A	32.4	Very low	36.1	Very low	97 Å²	97	137.8 Å²	137.8	80%	0.802	79%	0.792	S	S	*	*				162.1	146.2	123.9	0	0	0	0	0	114
378	F	30.3	Very low	35	Very low	177 Å²	177	134.6 Å²	134.6	78%	0.776	79%	0.788	S	S	*	*			trans	73	108.5	148.1	-132.5	-103.9	0	0	0	122.1
379	R	32	Very low	34.4	Very low	196 Å²	196	132.1 Å²	132.1	74%	0.74	79%	0.787	S	S	*	*			trans	24.8	118.7	139.9	-70.1	-177.1	176.2	166.8	-1.6	121.4
380	E	33.9	Very low	33.9	Very low	174 Å²	174	131.2 Å²	131.2	81%	0.813	78%	0.784	S	S	*	*				85.5	154.3	119.1	-154.8	164.9	-139.4	0	0	120.3
381	V	31.2	Very low	34.1	Very low	139 Å²	139	129.8 Å²	129.8	84%	0.842	78%	0.784	S	S	*	*			trans	73.7	112.9	178	-164.4	0	0	0	0	116.6
382	G	31.2	Very low	34.2	Very low	76 Å²	76	128.7 Å²	128.7	78%	0.784	78%	0.777	S	S	*	*			trans	-84.4	176.5	-168.6	0	0	0	0	0	118.1
383	S	29.6	Very low	33.7	Very low	126 Å²	126	130.9 Å²	130.9	88%	0.881	78%	0.78	S	S	*	*			trans	-154.8	162.8	141.5	-167.2	0	0	0	0	110.1
384	R	40.3	Very low	33.7	Very low	241 Å²	241	133.5 Å²	133.5	91%	0.909	79%	0.785	S	S	*	*			trans	-71.9	132.5	-175.4	-71.5	169.2	166.8	165.3	-6.5	111.6
385	G	30.2	Very low	33.6	Very low	71 Å²	71	134.7 Å²	134.7	73%	0.732	79%	0.785	S	S	*	*			trans	-148.4	54.6	172.3	0	0	0	0	0	111.6	A387	G385-A387 PolarHBondContact O-N 3.28Å
386	T	32.3	Very low	33.7	Very low	119 Å²	119	135.4 Å²	135.4	73%	0.73	78%	0.782	S	S	*	*			trans	-71.2	89.7	-178.3	41.5	0	0	0	0	112	I388	T386-I388 VanDerWaalsContact C-N 3.26Å; T386-I388 PolarHBondContact O-N 3.22Å
387	A	32.1	Very low	33.5	Very low	102 Å²	102	132.2 Å²	132.2	84%	0.843	78%	0.776	S	S	*	*			trans	-74.5	79.5	163.3	0	0	0	0	0	109.8	G385 C389	G385-A387 PolarHBondContact O-N 3.28Å; A387-C389 PolarHBondContact O-N 2.93Å; A387-C389 VanDerWaalsContact O-N 3.16Å
388	I	34.1	Very low	33.5	Very low	127 Å²	127	134.2 Å²	134.2	65%	0.651	77%	0.774	S	S	*	*			trans	-72.8	105.5	176.3	-61.8	170.4	0	0	0	108.4	T386 S390	T386-I388 VanDerWaalsContact C-N 3.26Å; T386-I388 PolarHBondContact O-N 3.22Å; I388-S390 WeakPolarHBondContact CG2-OG 3.48Å; I388-S390 PolarHBondContact O-N 3.26Å
389	C	35	Very low	33.7	Very low	108 Å²	108	131.6 Å²	131.6	73%	0.73	77%	0.774	S	S	*	*			trans	-75.6	82	163.4	-165.2	0	0	0	0	108.4	A387 S391	A387-C389 PolarHBondContact O-N 2.93Å; A387-C389 VanDerWaalsContact O-N 3.16Å; C389-S391 PolarHBondContact O-N 3.29Å; C389-S391 PolarHBondContact O-OG 3.28Å
390	S	31.3	Very low	33.8	Very low	95 Å²	95	127.3 Å²	127.3	66%	0.664	78%	0.776	S	S	*	*			trans	-57.7	109.7	-177.9	-84.5	0	0	0	0	110.8	I388 T392	I388-S390 WeakPolarHBondContact CG2-OG 3.48Å; I388-S390 PolarHBondContact O-N 3.26Å; S390-T392 PolarHBondContact O-N 2.88Å
391	S	43.9	Very low	33.8	Very low	102 Å²	102	123.9 Å²	123.9	71%	0.713	77%	0.774	S	S	*	*			trans	-87.6	76	179.4	-63.6	0	0	0	0	110.4	C389	C389-S391 PolarHBondContact O-N 3.29Å; C389-S391 PolarHBondContact O-OG 3.28Å
392	T	37.7	Very low	34	Very low	116 Å²	116	122.8 Å²	122.8	71%	0.712	77%	0.768	S	S	*	*			trans	-148.2	141.7	172	-35.6	0	0	0	0	110.3	S390	S390-T392 PolarHBondContact O-N 2.88Å
393	L	30.3	Very low	34.3	Very low	158 Å²	158	126.7 Å²	126.7	83%	0.827	77%	0.767	S	S	*	*			trans	76	127.5	-177.1	-49.8	162.2	0	0	0	112.8
394	L	34.3	Very low	34.7	Very low	155 Å²	155	126.7 Å²	126.7	81%	0.812	76%	0.757	S	S	*	*			cis	-145.3	0	5.7	-118	159	0	0	0	111	R293 Y352	R293-L394 PolarHBondContact NH1-OXT 2.89Å; R293-L394 PolarHBondContact NH2-OXT 3.36Å; Y352-L394 PolarHBondContact OH-O 3.08Å; Y352-L394 VanDerWaalsContact OH-O 3.04Å

Retrieved 394 of 394 residues in 301.6 ms (Link to these results)

U.S. Privacy Notice - Disclaimer / Registrations / Copyright Statement - Linking Policy - Notice of Privacy Practices (HIPAA) - Notice of Non‑Discrimination
© Copyright 2026 St. Jude Children's Research Hospital, a not-for-profit, section 501(c)(3).