A0A061IPK3_CRIGR Loading...

Lysosomal cobalamin transport escort protein LMBD1

AlphaFold DB , UniProt , Accession A0A061IPK3, Species CRIGR (Cricetulus griseus, Chinese hamster), Gene Lmbrd1, Length 538 aa.

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	48.6	Very low	63.4	Low	212 Å²	212	90.9 Å²	90.9	100%	1.044	58%	0.579	S	S	*	*				0	-48.7	0	-77.1	-167.1	-77.7	0	0	113	A3 A4 A5	M1-A3 PolarHBondContact O-N 3.44Å; M1-A4 PolarHBondContact O-N 3.22Å; M1-A5 WeakPolarHBondContact O-CB 3.42Å; M1-A5 PolarHBondContact O-N 3.28Å
2	A	53.5	Low	64.4	Low	87 Å²	87	97.3 Å²	97.3	72%	0.719	58%	0.584	S	S	*	*	H	α-helix	trans	-61.1	-41.1	179.4	0	0	0	0	0	114.6	A5 A6	A2-A5 PolarHBondContact O-N 3.09Å; A2-A6 WeakPolarHBondContact O-CB 3.42Å; A2-A6 PolarHBondContact O-N 3.09Å
3	A	53.3	Low	65.7	Low	76 Å²	76	95.3 Å²	95.3	63%	0.628	58%	0.576	S	S	*	*	H	α-helix	trans	-66.4	-43.7	177.5	0	0	0	0	0	112.8	M1 A5 A6 E7	M1-A3 PolarHBondContact O-N 3.44Å; A3-A5 VanDerWaalsContact C-N 3.34Å; A3-A5 PolarHBondContact O-N 3.36Å; A3-A6 PolarHBondContact O-N 3.33Å; A3-E7 WeakPolarHBondContact O-CG 3.28Å; A3-E7 PolarHBondContact O-N 2.92Å
4	A	52.7	Low	66.8	Low	69 Å²	69	96.2 Å²	96.2	57%	0.57	57%	0.574	S	S	*	*	H	α-helix	trans	-65.7	-35.9	176.5	0	0	0	0	0	112.7	M1 L8	M1-A4 PolarHBondContact O-N 3.22Å; A4-L8 WeakPolarHBondContact O-CB 3.22Å; A4-L8 PolarHBondContact O-N 2.91Å; A4-L8 VanDerWaalsContact O-N 3.09Å
5	A	59.3	Low	67.5	Low	54 Å²	54	97.1 Å²	97.1	45%	0.446	57%	0.568	S	S	.	*	H	α-helix	trans	-67.9	-39.1	172.8	0	0	0	0	0	111.7	M1 A2 A3 L8 V9	M1-A5 WeakPolarHBondContact O-CB 3.42Å; M1-A5 PolarHBondContact O-N 3.28Å; A2-A5 PolarHBondContact O-N 3.09Å; A3-A5 VanDerWaalsContact C-N 3.34Å; A3-A5 PolarHBondContact O-N 3.36Å; A5-L8 PolarHBondContact O-N 2.9Å; A5-V9 WeakPolarHBondContact O-CB 3.35Å; A5-V9 WeakPolarHBondContact O-CG2 3.37Å; A5-V9 PolarHBondContact O-N 2.88Å
6	A	67.6	Low	68.6	Low	49 Å²	49	93.1 Å²	93.1	41%	0.405	55%	0.554	S	S	.	*	H	α-helix	trans	-64.1	-45.8	176.1	0	0	0	0	0	111.9	A2 A3 L8 V9 I10	A2-A6 WeakPolarHBondContact O-CB 3.42Å; A2-A6 PolarHBondContact O-N 3.09Å; A3-A6 PolarHBondContact O-N 3.33Å; A6-L8 VanDerWaalsContact C-N 3.35Å; A6-L8 PolarHBondContact O-N 3.01Å; A6-V9 PolarHBondContact O-N 3.34Å; A6-I10 WeakPolarHBondContact O-CB 3.4Å; A6-I10 WeakPolarHBondContact O-CD1 3.4Å; A6-I10 WeakPolarHBondContact O-CG1 3.46Å; A6-I10 PolarHBondContact O-N 3.39Å
7	E	70	Confident	69.8	Low	135 Å²	135	94.8 Å²	94.8	63%	0.631	56%	0.559	S	S	*	*	H	α-helix	trans	-61.1	-41.4	175.7	-69.2	-64.9	157.1	0	0	112.2	A3 I10 G11	A3-E7 WeakPolarHBondContact O-CG 3.28Å; A3-E7 PolarHBondContact O-N 2.92Å; E7-I10 PolarHBondContact O-N 3.37Å; E7-G11 PolarHBondContact O-N 3.33Å
8	L	68.8	Low	70.7	Confident	109 Å²	109	92.2 Å²	92.2	57%	0.571	54%	0.542	S	S	*	.	H	α-helix	trans	-63.7	-46	175.7	-164.9	102.6	0	0	0	111.4	A4 A5 A6 I10 G11 W12	A4-L8 WeakPolarHBondContact O-CB 3.22Å; A4-L8 PolarHBondContact O-N 2.91Å; A4-L8 VanDerWaalsContact O-N 3.09Å; A5-L8 PolarHBondContact O-N 2.9Å; A6-L8 VanDerWaalsContact C-N 3.35Å; A6-L8 PolarHBondContact O-N 3.01Å; L8-I10 VanDerWaalsContact C-N 3.34Å; L8-I10 PolarHBondContact O-N 2.99Å; L8-G11 PolarHBondContact O-N 3.07Å; L8-W12 PolarHBondContact O-N 3.07Å
9	V	75.9	Confident	71.7	Confident	85 Å²	85	90.6 Å²	90.6	52%	0.515	53%	0.53	S	S	.	.	H	α-helix	trans	-62.5	-41.5	177.6	169.9	0	0	0	0	110.9	A5 A6 W12 C13	A5-V9 WeakPolarHBondContact O-CB 3.35Å; A5-V9 WeakPolarHBondContact O-CG2 3.37Å; A5-V9 PolarHBondContact O-N 2.88Å; A6-V9 PolarHBondContact O-N 3.34Å; V9-W12 PolarHBondContact O-N 3.06Å; V9-C13 WeakPolarHBondContact O-CB 3.36Å; V9-C13 PolarHBondContact O-N 3.46Å; V9-C13 PolarHBondContact O-SG 3.24Å
10	I	76.3	Confident	72.7	Confident	85 Å²	85	91.7 Å²	91.7	44%	0.436	53%	0.533	S	S	.	.	H	α-helix	trans	-61.3	-45.4	175.2	-69.5	162.6	0	0	0	110.3	A6 E7 L8 C13 I14	A6-I10 WeakPolarHBondContact O-CB 3.4Å; A6-I10 WeakPolarHBondContact O-CD1 3.4Å; A6-I10 WeakPolarHBondContact O-CG1 3.46Å; A6-I10 PolarHBondContact O-N 3.39Å; E7-I10 PolarHBondContact O-N 3.37Å; L8-I10 VanDerWaalsContact C-N 3.34Å; L8-I10 PolarHBondContact O-N 2.99Å; I10-C13 WeakPolarHBondContact O-CB 3.5Å; I10-C13 PolarHBondContact O-N 2.89Å; I10-I14 HydrophobicContact CG2-CD1 3.76Å; I10-I14 HydrophobicContact CG2-CG1 4.41Å; I10-I14 VanDerWaalsContact O-CG1 3.3Å; I10-I14 WeakPolarHBondContact O-CG1 3.47Å; I10-I14 PolarHBondContact O-N 2.84Å
11	G	71.6	Confident	73.6	Confident	39 Å²	39	90 Å²	90	40%	0.402	53%	0.53	S	S	.	.	H	α-helix	trans	-58.8	-47.5	176.2	0	0	0	0	0	113.2	E7 L8 C13 I14 F15	E7-G11 PolarHBondContact O-N 3.33Å; L8-G11 PolarHBondContact O-N 3.07Å; G11-C13 PolarHBondContact O-N 3.44Å; G11-I14 PolarHBondContact O-N 3.45Å; G11-F15 WeakPolarHBondContact O-CB 3.48Å; G11-F15 PolarHBondContact O-N 3.49Å
12	W	75.8	Confident	75.7	Confident	168 Å²	168	80.4 Å²	80.4	64%	0.636	48%	0.483	S	S	*	.	H	α-helix	trans	-64.9	-37	175.8	-73.7	113.1	0	0	0	112.8	L8 V9 F15 G16	L8-W12 PolarHBondContact O-N 3.07Å; V9-W12 PolarHBondContact O-N 3.06Å; W12-F15 HydrophobicContact CE3-CD1 4.43Å; W12-F15 HydrophobicContact CZ3-CD1 4.5Å; W12-F15 PolarHBondContact O-N 3.33Å; W12-G16 PolarHBondContact O-N 3.15Å
13	C	80.3	Confident	77.6	Confident	71 Å²	71	79.8 Å²	79.8	48%	0.48	47%	0.467	S	S	.	.	H	α-helix	trans	-63.6	-44.6	174.1	-77.6	0	0	0	0	111.9	V9 I10 G11 G16 L17	V9-C13 WeakPolarHBondContact O-CB 3.36Å; V9-C13 PolarHBondContact O-N 3.46Å; V9-C13 PolarHBondContact O-SG 3.24Å; I10-C13 WeakPolarHBondContact O-CB 3.5Å; I10-C13 PolarHBondContact O-N 2.89Å; G11-C13 PolarHBondContact O-N 3.44Å; C13-G16 PolarHBondContact O-N 3.29Å; C13-L17 WeakPolarHBondContact O-CB 3.39Å; C13-L17 VanDerWaalsContact O-CG 3.3Å; C13-L17 WeakPolarHBondContact O-CG 3.33Å; C13-L17 PolarHBondContact O-N 3.48Å
14	I	81.1	Confident	79.5	Confident	108 Å²	108	78.1 Å²	78.1	55%	0.554	45%	0.453	S	S	*	.	H	α-helix	trans	-63.7	-45.7	177.2	-67.8	166	0	0	0	110.4	I10 G11 G16 L17 L18	I10-I14 HydrophobicContact CG2-CD1 3.76Å; I10-I14 HydrophobicContact CG2-CG1 4.41Å; I10-I14 VanDerWaalsContact O-CG1 3.3Å; I10-I14 WeakPolarHBondContact O-CG1 3.47Å; I10-I14 PolarHBondContact O-N 2.84Å; G11-I14 PolarHBondContact O-N 3.45Å; I14-G16 PolarHBondContact O-N 3.22Å; I14-L17 PolarHBondContact O-N 3.27Å; I14-L18 WeakPolarHBondContact O-CB 3.27Å; I14-L18 PolarHBondContact O-N 2.86Å
15	F	78.3	Confident	81.5	Confident	109 Å²	109	76.9 Å²	76.9	48%	0.478	44%	0.435	S	S	.	.	H	α-helix	trans	-60.9	-44.3	176.1	-179.5	-100.4	0	0	0	112	G11 W12 L18 L19	G11-F15 WeakPolarHBondContact O-CB 3.48Å; G11-F15 PolarHBondContact O-N 3.49Å; W12-F15 HydrophobicContact CE3-CD1 4.43Å; W12-F15 HydrophobicContact CZ3-CD1 4.5Å; W12-F15 PolarHBondContact O-N 3.33Å; F15-L18 PolarHBondContact O-N 2.98Å; F15-L19 HydrophobicContact CZ-CD1 4.47Å; F15-L19 WeakPolarHBondContact O-CB 3.47Å; F15-L19 PolarHBondContact O-N 3.48Å
16	G	84.9	Confident	83.1	Confident	34 Å²	34	74.3 Å²	74.3	35%	0.351	41%	0.414	S	S	.	.	H	α-helix	trans	-61.7	-42.4	175.8	0	0	0	0	0	112.9	W12 C13 I14 L19 L20	W12-G16 PolarHBondContact O-N 3.15Å; C13-G16 PolarHBondContact O-N 3.29Å; I14-G16 PolarHBondContact O-N 3.22Å; G16-L19 PolarHBondContact O-N 3.01Å; G16-L20 WeakPolarHBondContact O-CB 3.34Å; G16-L20 PolarHBondContact O-N 2.92Å
17	L	88.1	Confident	84.3	Confident	121 Å²	121	78.4 Å²	78.4	63%	0.634	42%	0.419	S	S	*	.	H	α-helix	trans	-63.8	-42.9	175.4	-77.6	169	0	0	0	112.1	C13 I14 L20 A21	C13-L17 WeakPolarHBondContact O-CB 3.39Å; C13-L17 VanDerWaalsContact O-CG 3.3Å; C13-L17 WeakPolarHBondContact O-CG 3.33Å; C13-L17 PolarHBondContact O-N 3.48Å; I14-L17 PolarHBondContact O-N 3.27Å; L17-L20 PolarHBondContact O-N 3.25Å; L17-A21 WeakPolarHBondContact O-CB 3.35Å; L17-A21 PolarHBondContact O-N 3.34Å
18	L	86.4	Confident	85.4	Confident	49 Å²	49	77.4 Å²	77.4	26%	0.257	42%	0.416	S	S	.	.	H	α-helix	trans	-61.9	-46.9	176.5	-176.6	74.7	0	0	0	111.1	I14 F15 L20 A21 I22 A59 Y364	I14-L18 WeakPolarHBondContact O-CB 3.27Å; I14-L18 PolarHBondContact O-N 2.86Å; F15-L18 PolarHBondContact O-N 2.98Å; L18-L20 VanDerWaalsContact C-N 3.34Å; L18-L20 PolarHBondContact O-N 3.28Å; L18-A21 PolarHBondContact O-N 2.98Å; L18-I22 HydrophobicContact CG-CD1 4.24Å; L18-I22 WeakPolarHBondContact O-CG1 3.5Å; L18-I22 PolarHBondContact O-N 3.48Å; L18-A59 HydrophobicContact CD2-CB 4.24Å; L18-Y364 WeakPolarHBondContact CD2-OH 3.5Å
19	L	89	Confident	86.4	Confident	61 Å²	61	72.8 Å²	72.8	32%	0.319	39%	0.391	S	S	.	.	H	α-helix	trans	-61.1	-43.4	177.4	-171.2	113.6	0	0	0	111.3	F15 G16 A21 I22 L23 I56	F15-L19 HydrophobicContact CZ-CD1 4.47Å; F15-L19 WeakPolarHBondContact O-CB 3.47Å; F15-L19 PolarHBondContact O-N 3.48Å; G16-L19 PolarHBondContact O-N 3.01Å; L19-A21 VanDerWaalsContact C-N 3.35Å; L19-A21 PolarHBondContact O-N 3.29Å; L19-I22 PolarHBondContact O-N 2.87Å; L19-L23 HydrophobicContact CD2-CD1 3.87Å; L19-L23 HydrophobicContact CG-CD1 4.32Å; L19-L23 WeakPolarHBondContact O-CB 3.45Å; L19-L23 WeakPolarHBondContact O-CG 3.38Å; L19-L23 PolarHBondContact O-N 3.5Å; L19-I56 HydrophobicContact CD1-CD1 3.8Å; L19-I56 HydrophobicContact CD1-CG1 4.45Å
20	L	92.2	Very high	87.1	Confident	113 Å²	113	68.7 Å²	68.7	59%	0.592	37%	0.367	S	S	*	.	H	α-helix	trans	-62.7	-41.8	176.2	-170.1	152.4	0	0	0	111.4	G16 L17 L18 L23 A24	G16-L20 WeakPolarHBondContact O-CB 3.34Å; G16-L20 PolarHBondContact O-N 2.92Å; L17-L20 PolarHBondContact O-N 3.25Å; L18-L20 VanDerWaalsContact C-N 3.34Å; L18-L20 PolarHBondContact O-N 3.28Å; L20-L23 PolarHBondContact O-N 2.91Å; L20-A24 VanDerWaalsContact O-CB 3.27Å; L20-A24 WeakPolarHBondContact O-CB 3.32Å; L20-A24 PolarHBondContact O-N 2.9Å
21	A	91.2	Very high	87.7	Confident	56 Å²	56	71.2 Å²	71.2	46%	0.463	37%	0.371	S	S	.	.	H	α-helix	trans	-62.8	-42.4	176.2	0	0	0	0	0	112.1	L17 L18 L19 A24 F25	L17-A21 WeakPolarHBondContact O-CB 3.35Å; L17-A21 PolarHBondContact O-N 3.34Å; L18-A21 PolarHBondContact O-N 2.98Å; L19-A21 VanDerWaalsContact C-N 3.35Å; L19-A21 PolarHBondContact O-N 3.29Å; A21-A24 PolarHBondContact O-N 3.48Å; A21-F25 WeakPolarHBondContact O-CB 3.37Å; A21-F25 PolarHBondContact O-N 3.24Å
22	I	92.7	Very high	88.5	Confident	10 Å²	10	73.8 Å²	73.8	5%	0.051	37%	0.371	C	S	.	.	H	α-helix	trans	-62.3	-46.8	175.1	-69.7	169	0	0	0	110.7	L18 L19 F25 C26 A52 L55 I56 A59	L18-I22 HydrophobicContact CG-CD1 4.24Å; L18-I22 WeakPolarHBondContact O-CG1 3.5Å; L18-I22 PolarHBondContact O-N 3.48Å; L19-I22 PolarHBondContact O-N 2.87Å; I22-F25 PolarHBondContact O-N 3.29Å; I22-C26 PolarHBondContact O-N 3.35Å; I22-C26 PolarHBondContact O-SG 2.83Å; I22-A52 HydrophobicContact CG2-CB 4.23Å; I22-L55 HydrophobicContact CD1-CB 4.49Å; I22-L55 HydrophobicContact CG1-CB 4.48Å; I22-L55 HydrophobicContact CG2-CB 3.71Å; I22-L55 HydrophobicContact CG2-CD1 4.02Å; I22-I56 HydrophobicContact CD1-CG1 3.98Å; I22-I56 HydrophobicContact CG2-CG1 4.36Å; I22-A59 HydrophobicContact CD1-CB 4.2Å
23	L	93.8	Very high	89	Confident	75 Å²	75	66.8 Å²	66.8	39%	0.393	35%	0.345	S	S	.	.	H	α-helix	trans	-64	-42.9	178.5	-72.9	173.7	0	0	0	111.9	L19 L20 F25 C26 W27 A52	L19-L23 HydrophobicContact CD2-CD1 3.87Å; L19-L23 HydrophobicContact CG-CD1 4.32Å; L19-L23 WeakPolarHBondContact O-CB 3.45Å; L19-L23 WeakPolarHBondContact O-CG 3.38Å; L19-L23 PolarHBondContact O-N 3.5Å; L20-L23 PolarHBondContact O-N 2.91Å; L23-F25 VanDerWaalsContact C-N 3.35Å; L23-C26 PolarHBondContact O-N 2.89Å; L23-W27 VanDerWaalsContact O-CB 3.28Å; L23-W27 WeakPolarHBondContact O-CB 3.45Å; L23-W27 PolarHBondContact O-N 3.39Å; L23-A52 HydrophobicContact CD2-CB 3.92Å
24	A	94.4	Very high	89.3	Confident	40 Å²	40	64 Å²	64	33%	0.331	33%	0.325	S	S	.	.	H	α-helix	trans	-61.4	-44.1	175.4	0	0	0	0	0	111.2	L20 A21 W27 I28	L20-A24 VanDerWaalsContact O-CB 3.27Å; L20-A24 WeakPolarHBondContact O-CB 3.32Å; L20-A24 PolarHBondContact O-N 2.9Å; A21-A24 PolarHBondContact O-N 3.48Å; A24-W27 PolarHBondContact O-N 2.87Å; A24-I28 WeakPolarHBondContact O-CB 3.45Å; A24-I28 WeakPolarHBondContact O-CD1 3.29Å; A24-I28 WeakPolarHBondContact O-CG1 3.33Å; A24-I28 PolarHBondContact O-N 2.89Å
25	F	92.9	Very high	89.4	Confident	43 Å²	43	59.2 Å²	59.2	19%	0.189	30%	0.301	C	S	.	.	H	α-helix	trans	-59.5	-49.6	174.6	173.8	-96	0	0	0	111.6	A21 I22 L23 W27 I28 Y29 L55 I375 F376 M379	A21-F25 WeakPolarHBondContact O-CB 3.37Å; A21-F25 PolarHBondContact O-N 3.24Å; I22-F25 PolarHBondContact O-N 3.29Å; L23-F25 VanDerWaalsContact C-N 3.35Å; F25-W27 VanDerWaalsContact C-N 3.35Å; F25-W27 PolarHBondContact O-N 3.09Å; F25-I28 PolarHBondContact O-N 3.47Å; F25-Y29 WeakPolarHBondContact O-CB 3.43Å; F25-Y29 PolarHBondContact O-N 3.5Å; F25-L55 HydrophobicContact CD1-CD1 3.64Å; F25-L55 HydrophobicContact CE1-CD1 3.89Å; F25-I375 HydrophobicContact CE1-CG2 4.42Å; F25-I375 HydrophobicContact CZ-CG2 4.07Å; F25-F376 HydrophobicContact CE2-CE1 4.1Å; F25-F376 AromaticContact CE2-CZ 3.95Å; F25-F376 HydrophobicContact CE2-CZ 3.95Å; F25-M379 HydrophobicContact CZ-CE 4.13Å
26	C	93.9	Very high	89.2	Confident	0 Å²	0	62.4 Å²	62.4	0%	0	32%	0.317	C	S	.	.	H	α-helix	trans	-61.4	-43.1	178.9	-66.2	0	0	0	0	111.8	I22 L23 Y29 V30 I48 L51	I22-C26 PolarHBondContact O-N 3.35Å; I22-C26 PolarHBondContact O-SG 2.83Å; L23-C26 PolarHBondContact O-N 2.89Å; C26-Y29 PolarHBondContact O-N 3.33Å; C26-V30 WeakPolarHBondContact O-CB 3.36Å; C26-V30 WeakPolarHBondContact O-CG2 3.4Å; C26-V30 PolarHBondContact O-N 2.9Å; C26-I48 HydrophobicContact CB-CG2 3.95Å; C26-L51 HydrophobicContact CB-CD2 4.44Å
27	W	93.3	Very high	88.6	Confident	136 Å²	136	68.6 Å²	68.6	52%	0.515	33%	0.33	S	S	.	.	H	α-helix	trans	-61.4	-52.4	177.3	-179.4	-78.2	0	0	0	111.7	L23 A24 F25 Y29 V30 R31 I48	L23-W27 VanDerWaalsContact O-CB 3.28Å; L23-W27 WeakPolarHBondContact O-CB 3.45Å; L23-W27 PolarHBondContact O-N 3.39Å; A24-W27 PolarHBondContact O-N 2.87Å; F25-W27 VanDerWaalsContact C-N 3.35Å; F25-W27 PolarHBondContact O-N 3.09Å; W27-Y29 VanDerWaalsContact C-N 3.26Å; W27-Y29 PolarHBondContact O-N 3.37Å; W27-V30 PolarHBondContact O-N 3.35Å; W27-R31 VanDerWaalsContact O-CB 3.26Å; W27-R31 WeakPolarHBondContact O-CB 3.43Å; W27-R31 VanDerWaalsContact O-CG 3.29Å; W27-R31 WeakPolarHBondContact O-CG 3.44Å; W27-R31 PolarHBondContact O-N 3.21Å; W27-I48 HydrophobicContact CD2-CD1 4.32Å; W27-I48 HydrophobicContact CE3-CD1 3.78Å; W27-I48 HydrophobicContact CZ3-CD1 4.4Å
28	I	92.2	Very high	88	Confident	113 Å²	113	67.4 Å²	67.4	58%	0.579	32%	0.321	S	S	*	.	H	α-helix	trans	-59.5	-42.6	178.5	-69.4	166.2	0	0	0	109.9	A24 F25 K32	A24-I28 WeakPolarHBondContact O-CB 3.45Å; A24-I28 WeakPolarHBondContact O-CD1 3.29Å; A24-I28 WeakPolarHBondContact O-CG1 3.33Å; A24-I28 PolarHBondContact O-N 2.89Å; F25-I28 PolarHBondContact O-N 3.47Å; I28-K32 WeakPolarHBondContact O-CB 3.26Å; I28-K32 PolarHBondContact O-N 3.06Å
29	Y	89.8	Confident	87.4	Confident	12 Å²	12	67.5 Å²	67.5	5%	0.047	33%	0.326	C	S	.	.	H	α-helix	trans	-61.5	-54.6	179.5	175.8	-105.1	0	0	0	111.9	F25 C26 W27 R31 K32 Y33 L51 M379 L410 L414	F25-Y29 WeakPolarHBondContact O-CB 3.43Å; F25-Y29 PolarHBondContact O-N 3.5Å; C26-Y29 PolarHBondContact O-N 3.33Å; W27-Y29 VanDerWaalsContact C-N 3.26Å; W27-Y29 PolarHBondContact O-N 3.37Å; Y29-R31 PolarHBondContact O-N 2.93Å; Y29-K32 WeakPolarHBondContact O-CB 3.26Å; Y29-K32 PolarHBondContact O-N 3.15Å; Y29-Y33 HydrophobicContact CD2-CD2 4.06Å; Y29-Y33 AromaticContact CD2-CE2 3.88Å; Y29-Y33 HydrophobicContact CD2-CE2 3.88Å; Y29-Y33 AromaticContact CE2-CD2 3.61Å; Y29-Y33 HydrophobicContact CE2-CD2 3.61Å; Y29-Y33 AromaticContact CE2-CE2 3.34Å; Y29-Y33 HydrophobicContact CE2-CE2 3.34Å; Y29-Y33 AromaticContact CZ-CD2 4Å; Y29-Y33 WeakPolarHBondContact O-CD2 3.45Å; Y29-Y33 PolarHBondContact O-N 2.66Å; Y29-L51 HydrophobicContact CD1-CD2 3.55Å; Y29-L51 HydrophobicContact CE1-CD2 4.06Å; Y29-L51 HydrophobicContact CG-CD2 4.33Å; Y29-M379 HydrophobicContact CD2-SD 3.43Å; Y29-M379 WeakPolarHBondContact CD2-SD 3.48Å; Y29-M379 HydrophobicContact CE2-CG 3.93Å; Y29-M379 HydrophobicContact CE2-SD 3.08Å; Y29-M379 WeakPolarHBondContact CE2-SD 2.86Å; Y29-M379 HydrophobicContact CG-SD 4.47Å; Y29-L410 HydrophobicContact CE1-CD2 4.5Å; Y29-L410 WeakPolarHBondContact OH-CD1 3.48Å; Y29-L410 WeakPolarHBondContact OH-CD2 3.11Å; Y29-L410 VanDerWaalsContact OH-CG 3.23Å; Y29-L410 WeakPolarHBondContact OH-CG 3.24Å; Y29-L414 HydrophobicContact CE1-CD1 3.64Å; Y29-L414 HydrophobicContact CE2-CD1 4.36Å; Y29-L414 VanDerWaalsContact CZ-CD1 3.44Å; Y29-L414 WeakPolarHBondContact OH-CD1 3.35Å
30	V	90.6	Very high	87.1	Confident	0 Å²	0	67.7 Å²	67.7	0%	0	33%	0.325	C	S	.	.	H	α-helix	trans	-62.4	-47.6	-178.4	169.3	0	0	0	0	110.7	C26 W27 K32 Y33 Q34 T44 A47 I48 L407	C26-V30 WeakPolarHBondContact O-CB 3.36Å; C26-V30 WeakPolarHBondContact O-CG2 3.4Å; C26-V30 PolarHBondContact O-N 2.9Å; W27-V30 PolarHBondContact O-N 3.35Å; V30-K32 PolarHBondContact O-N 2.97Å; V30-Y33 PolarHBondContact O-N 3.4Å; V30-Y33 VanDerWaalsContact O-N 3.12Å; V30-Q34 VanDerWaalsContact O-CB 3.24Å; V30-Q34 WeakPolarHBondContact O-CB 3.5Å; V30-Q34 PolarHBondContact O-N 3.11Å; V30-T44 HydrophobicContact CG1-CG2 4.34Å; V30-A47 HydrophobicContact CG1-CB 4.22Å; V30-A47 HydrophobicContact CG2-CB 3.88Å; V30-I48 HydrophobicContact CB-CD1 4.44Å; V30-I48 HydrophobicContact CB-CG1 3.83Å; V30-I48 HydrophobicContact CG1-CD1 4.48Å; V30-I48 HydrophobicContact CG1-CG1 4.12Å; V30-I48 HydrophobicContact CG2-CG1 3.74Å; V30-L407 HydrophobicContact CG1-CD1 4.43Å; V30-L407 HydrophobicContact CG1-CD2 3.91Å
31	R	89.9	Confident	86.8	Confident	137 Å²	137	67.4 Å²	67.4	52%	0.517	33%	0.328	S	S	.	.	H	α-helix	trans	-60.1	-30.7	177.5	-75.7	-73.9	-171.7	169.3	0.6	113.3	W27 Y29 Y33	W27-R31 VanDerWaalsContact O-CB 3.26Å; W27-R31 WeakPolarHBondContact O-CB 3.43Å; W27-R31 VanDerWaalsContact O-CG 3.29Å; W27-R31 WeakPolarHBondContact O-CG 3.44Å; W27-R31 PolarHBondContact O-N 3.21Å; Y29-R31 PolarHBondContact O-N 2.93Å; R31-Y33 VanDerWaalsContact C-N 3.33Å
32	K	88.1	Confident	86.7	Confident	94 Å²	94	67.9 Å²	67.9	41%	0.409	33%	0.325	S	S	.	.	H	α-helix	trans	-68.3	-31.2	178.5	179.8	175.5	179.6	176.7	0	112.7	I28 Y29 V30 R399 G400	I28-K32 WeakPolarHBondContact O-CB 3.26Å; I28-K32 PolarHBondContact O-N 3.06Å; Y29-K32 WeakPolarHBondContact O-CB 3.26Å; Y29-K32 PolarHBondContact O-N 3.15Å; V30-K32 PolarHBondContact O-N 2.97Å; K32-R399 HydrophobicContact CG-CG 4.05Å; K32-R399 WeakPolarHBondContact O-CG 3.47Å; K32-G400 PolarHBondContact O-N 3.42Å
33	Y	85.6	Confident	86.6	Confident	20 Å²	20	67.4 Å²	67.4	8%	0.078	32%	0.322	C	S	.	.	H	α-helix	trans	-104.4	-27.1	-176.5	-72.2	-78.6	0	0	0	113.8	Y29 V30 R31 S35 I397 T402	Y29-Y33 HydrophobicContact CD2-CD2 4.06Å; Y29-Y33 AromaticContact CD2-CE2 3.88Å; Y29-Y33 HydrophobicContact CD2-CE2 3.88Å; Y29-Y33 AromaticContact CE2-CD2 3.61Å; Y29-Y33 HydrophobicContact CE2-CD2 3.61Å; Y29-Y33 AromaticContact CE2-CE2 3.34Å; Y29-Y33 HydrophobicContact CE2-CE2 3.34Å; Y29-Y33 AromaticContact CZ-CD2 4Å; Y29-Y33 WeakPolarHBondContact O-CD2 3.45Å; Y29-Y33 PolarHBondContact O-N 2.66Å; V30-Y33 PolarHBondContact O-N 3.4Å; V30-Y33 VanDerWaalsContact O-N 3.12Å; R31-Y33 VanDerWaalsContact C-N 3.33Å; Y33-S35 PolarHBondContact O-N 2.91Å; Y33-I397 HydrophobicContact CD1-CG2 3.65Å; Y33-I397 HydrophobicContact CE1-CG2 3.94Å; Y33-I397 HydrophobicContact CG-CG2 4.48Å; Y33-T402 WeakPolarHBondContact O-CB 3.47Å; Y33-T402 PolarHBondContact O-N 2.85Å; Y33-T402 PolarHBondContact O-OG1 2.95Å
34	Q	86.9	Confident	86.5	Confident	13 Å²	13	64.5 Å²	64.5	6%	0.061	31%	0.308	C	S	.	.	B	Isolated β-bridge	trans	-51.1	133.8	176.5	177.7	-177.5	-6.4	0	0	112.3	V30 S39 T44 G400 L407	V30-Q34 VanDerWaalsContact O-CB 3.24Å; V30-Q34 WeakPolarHBondContact O-CB 3.5Å; V30-Q34 PolarHBondContact O-N 3.11Å; Q34-S39 PolarHBondContact NE2-OG 2.93Å; Q34-T44 HydrophobicContact CG-CG2 3.99Å; Q34-T44 VanDerWaalsContact NE2-CG2 3.25Å; Q34-G400 CarbonylContact O-C 3.38Å; Q34-G400 VanDerWaalsContact O-C 3.23Å; Q34-G400 VanDerWaalsContact O-CA 3.26Å; Q34-G400 WeakPolarHBondContact O-CA 3.38Å; Q34-L407 HydrophobicContact CB-CD2 4.34Å
35	S	82.4	Confident	86.4	Confident	7 Å²	7	66.8 Å²	66.8	5%	0.049	32%	0.317	C	S	.	.			trans	-60.9	134.7	171.4	-175.8	0	0	0	0	111.4	Y33 R37 E38 S39 G400 T402	Y33-S35 PolarHBondContact O-N 2.91Å; S35-R37 VanDerWaalsContact C-N 3.33Å; S35-R37 PolarHBondContact OG-N 3.37Å; S35-E38 PolarHBondContact OG-N 3.04Å; S35-S39 WeakPolarHBondContact O-CB 3.38Å; S35-G400 WeakPolarHBondContact CA-O 3.49Å; S35-T402 WeakPolarHBondContact CB-O 3.48Å; S35-T402 PolarHBondContact N-O 3.41Å
36	Q	75.5	Confident	86.4	Confident	176 Å²	176	64.8 Å²	64.8	82%	0.822	31%	0.309	S	S	*	.	S	Bend	trans	-74.9	-22.4	173.6	-68.8	-179.3	-6.8	0	0	113.3	G400	Q36-G400 PolarHBondContact N-O 2.85Å
37	R	71.4	Confident	86.4	Confident	165 Å²	165	64.8 Å²	64.8	62%	0.623	31%	0.309	S	S	*	.	S	Bend	trans	-91.7	-43.3	-175.6	-67.7	-175	-179.4	-179.1	-1.7	113.1	S35	S35-R37 VanDerWaalsContact C-N 3.33Å; S35-R37 PolarHBondContact OG-N 3.37Å
38	E	75.8	Confident	86.4	Confident	95 Å²	95	59.4 Å²	59.4	44%	0.444	29%	0.29	S	S	.	.	S	Bend	trans	-107.1	31.2	-173.2	-64.7	171.7	-171.7	0	0	111.7	S35 R403 P404	S35-E38 PolarHBondContact OG-N 3.04Å; E38-R403 WeakPolarHBondContact OE2-CG 3.46Å; E38-R403 IonicContact OE2-NE 3.1Å; E38-R403 PolarHBondContact OE2-NE 3.39Å; E38-P404 WeakPolarHBondContact O-CG 3.2Å
39	S	73.5	Confident	86.6	Confident	52 Å²	52	58.5 Å²	58.5	36%	0.364	28%	0.282	S	S	.	.			trans	-84.4	125.7	-168.3	124.8	0	0	0	0	111.4	Q34 S35	Q34-S39 PolarHBondContact NE2-OG 2.93Å; S35-S39 WeakPolarHBondContact O-CB 3.38Å
40	E	82.2	Confident	86.8	Confident	65 Å²	65	58 Å²	58	30%	0.304	28%	0.28	S	S	.	.			trans	-123.4	143.3	-176.2	-77.2	-75.9	177.8	0	0	112.7	S43 T44 Y120 K123	E40-S43 PolarHBondContact O-OG 3.33Å; E40-S43 VanDerWaalsContact O-OG 3.05Å; E40-T44 WeakPolarHBondContact O-CB 3.46Å; E40-T44 WeakPolarHBondContact O-CG2 3.39Å; E40-T44 PolarHBondContact O-N 3.19Å; E40-T44 PolarHBondContact O-OG1 3.42Å; E40-Y120 HydrophobicContact CB-CE1 3.59Å; E40-Y120 VanDerWaalsContact CB-OH 3.3Å; E40-Y120 WeakPolarHBondContact CB-OH 3.5Å; E40-Y120 HydrophobicContact CG-CD1 4.38Å; E40-Y120 HydrophobicContact CG-CE1 3.54Å; E40-K123 IonicContact OE1-NZ 2.8Å; E40-K123 PolarHBondContact OE1-NZ 2.83Å; E40-K123 IonicContact OE2-NZ 3.91Å
41	V	87.1	Confident	86.9	Confident	106 Å²	106	58 Å²	58	64%	0.642	28%	0.28	S	S	*	.	H	α-helix	trans	-72.2	-40.1	-170.8	-177.1	0	0	0	0	111.8	T44 V45	V41-T44 WeakPolarHBondContact CA-OG1 3.31Å; V41-T44 PolarHBondContact O-N 3.49Å; V41-T44 PolarHBondContact O-OG1 3.47Å; V41-V45 HydrophobicContact CG1-CG2 4.12Å; V41-V45 WeakPolarHBondContact O-CB 3.45Å; V41-V45 VanDerWaalsContact O-CG2 3.26Å; V41-V45 WeakPolarHBondContact O-CG2 3.48Å; V41-V45 PolarHBondContact O-N 2.68Å
42	V	89.8	Confident	87.2	Confident	67 Å²	67	51.7 Å²	51.7	41%	0.406	26%	0.257	S	S	.	.	H	α-helix	trans	-69.4	-42.4	-175.7	-173.8	0	0	0	0	111.4	T44 T46 V116 Y120	V42-T44 VanDerWaalsContact C-N 3.33Å; V42-T44 PolarHBondContact O-N 3.4Å; V42-T46 VanDerWaalsContact O-CB 3.24Å; V42-T46 WeakPolarHBondContact O-CB 3.48Å; V42-T46 PolarHBondContact O-N 3.48Å; V42-T46 PolarHBondContact O-OG1 3.44Å; V42-V116 HydrophobicContact CG1-CG1 4.33Å; V42-V116 HydrophobicContact CG1-CG2 4.25Å; V42-Y120 HydrophobicContact CB-CE2 4.29Å; V42-Y120 VanDerWaalsContact CB-OH 3.31Å; V42-Y120 WeakPolarHBondContact CB-OH 3.43Å
43	S	89.4	Confident	87.5	Confident	0 Å²	0	47.7 Å²	47.7	0%	0	24%	0.241	C	C	.	.	H	α-helix	trans	-63.7	-39.3	176.4	56.5	0	0	0	0	112.2	E40 T46 A47 Y120	E40-S43 PolarHBondContact O-OG 3.33Å; E40-S43 VanDerWaalsContact O-OG 3.05Å; S43-T46 PolarHBondContact O-N 3.04Å; S43-A47 VanDerWaalsContact O-CB 3.31Å; S43-A47 WeakPolarHBondContact O-CB 3.38Å; S43-A47 PolarHBondContact O-N 3Å; S43-Y120 PolarHBondContact N-OH 3.04Å
44	T	91.1	Very high	87.9	Confident	14 Å²	14	46.9 Å²	46.9	9%	0.086	24%	0.238	C	C	.	.	H	α-helix	trans	-72.8	-42.9	-178.7	52.7	0	0	0	0	112.4	V30 Q34 E40 V41 V42 T46 A47 I48 L407	V30-T44 HydrophobicContact CG1-CG2 4.34Å; Q34-T44 HydrophobicContact CG-CG2 3.99Å; Q34-T44 VanDerWaalsContact NE2-CG2 3.25Å; E40-T44 WeakPolarHBondContact O-CB 3.46Å; E40-T44 WeakPolarHBondContact O-CG2 3.39Å; E40-T44 PolarHBondContact O-N 3.19Å; E40-T44 PolarHBondContact O-OG1 3.42Å; V41-T44 WeakPolarHBondContact CA-OG1 3.31Å; V41-T44 PolarHBondContact O-N 3.49Å; V41-T44 PolarHBondContact O-OG1 3.47Å; V42-T44 VanDerWaalsContact C-N 3.33Å; V42-T44 PolarHBondContact O-N 3.4Å; T44-T46 VanDerWaalsContact C-N 3.29Å; T44-T46 PolarHBondContact O-N 3.04Å; T44-A47 PolarHBondContact O-N 3.33Å; T44-I48 VanDerWaalsContact O-CG1 3.24Å; T44-I48 WeakPolarHBondContact O-CG1 3.44Å; T44-I48 PolarHBondContact O-N 3.38Å; T44-L407 HydrophobicContact CG2-CD2 4.39Å
45	V	93	Very high	88.2	Confident	87 Å²	87	46.5 Å²	46.5	53%	0.527	24%	0.236	S	C	.	.	H	α-helix	trans	-60.2	-42.2	171.8	172	0	0	0	0	110.5	V41 I48 F49	V41-V45 HydrophobicContact CG1-CG2 4.12Å; V41-V45 WeakPolarHBondContact O-CB 3.45Å; V41-V45 VanDerWaalsContact O-CG2 3.26Å; V41-V45 WeakPolarHBondContact O-CG2 3.48Å; V41-V45 PolarHBondContact O-N 2.68Å; V45-I48 PolarHBondContact O-N 3.16Å; V45-F49 VanDerWaalsContact O-CB 3.22Å; V45-F49 WeakPolarHBondContact O-CB 3.4Å; V45-F49 PolarHBondContact O-N 2.95Å
46	T	93.9	Very high	88.8	Confident	1 Å²	1	47.9 Å²	47.9	1%	0.006	24%	0.242	C	C	.	.	H	α-helix	trans	-62.8	-46.2	177.4	-62.7	0	0	0	0	112.4	V42 S43 T44 F49 S50 W112 I113 V116 L408	V42-T46 VanDerWaalsContact O-CB 3.24Å; V42-T46 WeakPolarHBondContact O-CB 3.48Å; V42-T46 PolarHBondContact O-N 3.48Å; V42-T46 PolarHBondContact O-OG1 3.44Å; S43-T46 PolarHBondContact O-N 3.04Å; T44-T46 VanDerWaalsContact C-N 3.29Å; T44-T46 PolarHBondContact O-N 3.04Å; T46-F49 PolarHBondContact O-N 3Å; T46-S50 VanDerWaalsContact O-CB 3.29Å; T46-S50 WeakPolarHBondContact O-CB 3.22Å; T46-S50 PolarHBondContact O-N 2.94Å; T46-S50 PolarHBondContact O-OG 3.29Å; T46-W112 HydrophobicContact CG2-CG 4.5Å; T46-W112 VanDerWaalsContact CG2-NE1 3.33Å; T46-W112 PolarHBondContact OG1-NE1 3.21Å; T46-I113 HydrophobicContact CG2-CG1 4.16Å; T46-V116 HydrophobicContact CG2-CB 4.44Å; T46-V116 HydrophobicContact CG2-CG2 4.26Å; T46-L408 HydrophobicContact CG2-CD2 3.75Å
47	A	93.1	Very high	89.6	Confident	0 Å²	0	39.6 Å²	39.6	0%	0	20%	0.204	C	C	.	.	H	α-helix	trans	-59.1	-48.8	175.7	0	0	0	0	0	111.7	V30 S43 T44 S50 L51 L407 C411	V30-A47 HydrophobicContact CG1-CB 4.22Å; V30-A47 HydrophobicContact CG2-CB 3.88Å; S43-A47 VanDerWaalsContact O-CB 3.31Å; S43-A47 WeakPolarHBondContact O-CB 3.38Å; S43-A47 PolarHBondContact O-N 3Å; T44-A47 PolarHBondContact O-N 3.33Å; A47-S50 PolarHBondContact O-OG 3.45Å; A47-L51 WeakPolarHBondContact O-CB 3.42Å; A47-L51 PolarHBondContact O-N 3.14Å; A47-L51 VanDerWaalsContact O-N 3.16Å; A47-L407 HydrophobicContact CB-CD2 4.43Å; A47-L407 HydrophobicContact CB-CG 4.34Å; A47-C411 HydrophobicContact CB-CB 4.33Å; A47-C411 VanDerWaalsContact CB-SG 3.54Å
48	I	94.3	Very high	90.5	Very high	23 Å²	23	31.8 Å²	31.8	12%	0.118	18%	0.175	C	C	.	.	H	α-helix	trans	-62.2	-48.1	178	-66.7	167.8	0	0	0	110.9	C26 W27 V30 T44 V45 A52	C26-I48 HydrophobicContact CB-CG2 3.95Å; W27-I48 HydrophobicContact CD2-CD1 4.32Å; W27-I48 HydrophobicContact CE3-CD1 3.78Å; W27-I48 HydrophobicContact CZ3-CD1 4.4Å; V30-I48 HydrophobicContact CB-CD1 4.44Å; V30-I48 HydrophobicContact CB-CG1 3.83Å; V30-I48 HydrophobicContact CG1-CD1 4.48Å; V30-I48 HydrophobicContact CG1-CG1 4.12Å; V30-I48 HydrophobicContact CG2-CG1 3.74Å; T44-I48 VanDerWaalsContact O-CG1 3.24Å; T44-I48 WeakPolarHBondContact O-CG1 3.44Å; T44-I48 PolarHBondContact O-N 3.38Å; V45-I48 PolarHBondContact O-N 3.16Å; I48-A52 WeakPolarHBondContact O-CB 3.38Å; I48-A52 PolarHBondContact O-N 2.86Å
49	F	95.1	Very high	91.2	Very high	95 Å²	95	28 Å²	28	42%	0.417	16%	0.16	S	C	.	.	H	α-helix	trans	-62.1	-50.5	-178.4	176.8	-105.5	0	0	0	112	V45 T46 L51 A52 V53 V104	V45-F49 VanDerWaalsContact O-CB 3.22Å; V45-F49 WeakPolarHBondContact O-CB 3.4Å; V45-F49 PolarHBondContact O-N 2.95Å; T46-F49 PolarHBondContact O-N 3Å; F49-L51 VanDerWaalsContact C-N 3.35Å; F49-L51 PolarHBondContact O-N 2.97Å; F49-A52 PolarHBondContact O-N 2.91Å; F49-V53 HydrophobicContact CD1-CG2 4.48Å; F49-V53 HydrophobicContact CD2-CG2 4.25Å; F49-V53 HydrophobicContact CE1-CG2 4.11Å; F49-V53 HydrophobicContact CE2-CG2 3.85Å; F49-V53 HydrophobicContact CZ-CG2 3.78Å; F49-V53 WeakPolarHBondContact O-CG2 3.33Å; F49-V53 PolarHBondContact O-N 3.37Å; F49-V104 HydrophobicContact CE1-CG1 4.06Å; F49-V104 HydrophobicContact CZ-CG1 3.88Å
50	S	94.1	Very high	91.9	Very high	0 Å²	0	27 Å²	27	0%	0	15%	0.15	C	C	.	.	H	α-helix	trans	-58.5	-44.6	179.6	64.6	0	0	0	0	112.6	T46 A47 A54	T46-S50 VanDerWaalsContact O-CB 3.29Å; T46-S50 WeakPolarHBondContact O-CB 3.22Å; T46-S50 PolarHBondContact O-N 2.94Å; T46-S50 PolarHBondContact O-OG 3.29Å; A47-S50 PolarHBondContact O-OG 3.45Å; S50-A54 PolarHBondContact O-N 3.46Å
51	L	93.6	Very high	92.3	Very high	1 Å²	1	24 Å²	24	1%	0.005	14%	0.136	C	C	.	.	H	α-helix	trans	-69.4	-40	178.7	-172.1	62.7	0	0	0	111.4	C26 Y29 A47 F49 A54 L55 L414	C26-L51 HydrophobicContact CB-CD2 4.44Å; Y29-L51 HydrophobicContact CD1-CD2 3.55Å; Y29-L51 HydrophobicContact CE1-CD2 4.06Å; Y29-L51 HydrophobicContact CG-CD2 4.33Å; A47-L51 WeakPolarHBondContact O-CB 3.42Å; A47-L51 PolarHBondContact O-N 3.14Å; A47-L51 VanDerWaalsContact O-N 3.16Å; F49-L51 VanDerWaalsContact C-N 3.35Å; F49-L51 PolarHBondContact O-N 2.97Å; L51-A54 PolarHBondContact O-N 2.73Å; L51-L55 HydrophobicContact CG-CD1 4.29Å; L51-L55 VanDerWaalsContact O-CG 3.31Å; L51-L55 WeakPolarHBondContact O-CG 3.25Å; L51-L55 PolarHBondContact O-N 2.62Å; L51-L414 HydrophobicContact CD1-CB 4.11Å
52	A	95.4	Very high	92.3	Very high	4 Å²	4	19.1 Å²	19.1	3%	0.033	11%	0.107	C	C	.	.	H	α-helix	trans	-61.8	-45.3	176.9	0	0	0	0	0	111.6	I22 L23 I48 F49 A54 L55 I56	I22-A52 HydrophobicContact CG2-CB 4.23Å; L23-A52 HydrophobicContact CD2-CB 3.92Å; I48-A52 WeakPolarHBondContact O-CB 3.38Å; I48-A52 PolarHBondContact O-N 2.86Å; F49-A52 PolarHBondContact O-N 2.91Å; A52-A54 VanDerWaalsContact C-N 3.32Å; A52-A54 PolarHBondContact O-N 2.68Å; A52-L55 PolarHBondContact O-N 2.97Å; A52-I56 WeakPolarHBondContact O-CB 3.46Å; A52-I56 WeakPolarHBondContact O-CD1 3.33Å; A52-I56 WeakPolarHBondContact O-CG1 3.42Å; A52-I56 PolarHBondContact O-N 2.88Å
53	V	95	Very high	92.2	Very high	11 Å²	11	18.3 Å²	18.3	7%	0.067	10%	0.102	C	C	.	.	H	α-helix	trans	-60	-43	176.9	174	0	0	0	0	111	F49 L55 I56 A57 L101 V104 I105	F49-V53 HydrophobicContact CD1-CG2 4.48Å; F49-V53 HydrophobicContact CD2-CG2 4.25Å; F49-V53 HydrophobicContact CE1-CG2 4.11Å; F49-V53 HydrophobicContact CE2-CG2 3.85Å; F49-V53 HydrophobicContact CZ-CG2 3.78Å; F49-V53 WeakPolarHBondContact O-CG2 3.33Å; F49-V53 PolarHBondContact O-N 3.37Å; V53-L55 PolarHBondContact O-N 3.19Å; V53-I56 PolarHBondContact O-N 3.4Å; V53-A57 WeakPolarHBondContact O-CB 3.48Å; V53-A57 PolarHBondContact O-N 3.02Å; V53-L101 HydrophobicContact CG1-CD2 4.45Å; V53-V104 HydrophobicContact CB-CG1 4.46Å; V53-V104 HydrophobicContact CG1-CB 4.16Å; V53-V104 HydrophobicContact CG1-CG1 3.84Å; V53-V104 HydrophobicContact CG2-CG1 3.9Å; V53-I105 HydrophobicContact CG1-CG1 3.73Å
54	A	94	Very high	92.2	Very high	2 Å²	2	18.4 Å²	18.4	2%	0.017	10%	0.102	C	C	.	.	H	α-helix	trans	-61.4	-44.8	177.2	0	0	0	0	0	111.9	S50 L51 A52 A57 S58 L415 V418	S50-A54 PolarHBondContact O-N 3.46Å; L51-A54 PolarHBondContact O-N 2.73Å; A52-A54 VanDerWaalsContact C-N 3.32Å; A52-A54 PolarHBondContact O-N 2.68Å; A54-A57 WeakPolarHBondContact O-CB 3.47Å; A54-A57 PolarHBondContact O-N 2.85Å; A54-S58 PolarHBondContact O-N 3.43Å; A54-S58 PolarHBondContact O-OG 2.88Å; A54-L415 HydrophobicContact CB-CB 4.15Å; A54-L415 HydrophobicContact CB-CD1 4.39Å; A54-L415 HydrophobicContact CB-CG 3.86Å; A54-V418 HydrophobicContact CB-CB 4.29Å; A54-V418 HydrophobicContact CB-CG1 3.94Å; A54-V418 WeakPolarHBondContact O-CG1 3.49Å
55	L	93.5	Very high	92	Very high	5 Å²	5	17.8 Å²	17.8	3%	0.026	10%	0.098	C	C	.	.	H	α-helix	trans	-68.7	-36.4	178.7	-66.7	177.5	0	0	0	112.7	I22 F25 L51 A52 V53 A57 S58 A59 M372 I375 V418	I22-L55 HydrophobicContact CD1-CB 4.49Å; I22-L55 HydrophobicContact CG1-CB 4.48Å; I22-L55 HydrophobicContact CG2-CB 3.71Å; I22-L55 HydrophobicContact CG2-CD1 4.02Å; F25-L55 HydrophobicContact CD1-CD1 3.64Å; F25-L55 HydrophobicContact CE1-CD1 3.89Å; L51-L55 HydrophobicContact CG-CD1 4.29Å; L51-L55 VanDerWaalsContact O-CG 3.31Å; L51-L55 WeakPolarHBondContact O-CG 3.25Å; L51-L55 PolarHBondContact O-N 2.62Å; A52-L55 PolarHBondContact O-N 2.97Å; V53-L55 PolarHBondContact O-N 3.19Å; L55-A57 VanDerWaalsContact C-N 3.33Å; L55-S58 PolarHBondContact O-N 3.07Å; L55-A59 VanDerWaalsContact O-CB 3.27Å; L55-A59 WeakPolarHBondContact O-CB 3.47Å; L55-A59 PolarHBondContact O-N 2.93Å; L55-M372 HydrophobicContact CD2-CE 4.45Å; L55-I375 HydrophobicContact CD2-CD1 3.27Å; L55-I375 HydrophobicContact CD2-CG1 4.46Å; L55-V418 HydrophobicContact CD2-CG1 4.22Å; L55-V418 HydrophobicContact CD2-CG2 4.1Å
56	I	93.7	Very high	91.6	Very high	36 Å²	36	16.2 Å²	16.2	19%	0.185	9%	0.085	C	C	.	.	H	α-helix	trans	-63.4	-42.6	173.2	-68.4	163.8	0	0	0	109.9	L19 I22 A52 V53 S58 A59 L60 L101	L19-I56 HydrophobicContact CD1-CD1 3.8Å; L19-I56 HydrophobicContact CD1-CG1 4.45Å; I22-I56 HydrophobicContact CD1-CG1 3.98Å; I22-I56 HydrophobicContact CG2-CG1 4.36Å; A52-I56 WeakPolarHBondContact O-CB 3.46Å; A52-I56 WeakPolarHBondContact O-CD1 3.33Å; A52-I56 WeakPolarHBondContact O-CG1 3.42Å; A52-I56 PolarHBondContact O-N 2.88Å; V53-I56 PolarHBondContact O-N 3.4Å; I56-S58 PolarHBondContact O-N 3.28Å; I56-A59 PolarHBondContact O-N 3.36Å; I56-L60 PolarHBondContact O-N 2.98Å; I56-L101 HydrophobicContact CB-CD2 4.42Å; I56-L101 HydrophobicContact CG2-CD1 3.99Å; I56-L101 HydrophobicContact CG2-CD2 3.77Å
57	A	92.3	Very high	91.2	Very high	2 Å²	2	18.3 Å²	18.3	2%	0.017	10%	0.095	C	C	.	.	H	α-helix	trans	-61.7	-40.8	175.8	0	0	0	0	0	112.6	V53 A54 L55 L60 L101 Y102 I105	V53-A57 WeakPolarHBondContact O-CB 3.48Å; V53-A57 PolarHBondContact O-N 3.02Å; A54-A57 WeakPolarHBondContact O-CB 3.47Å; A54-A57 PolarHBondContact O-N 2.85Å; L55-A57 VanDerWaalsContact C-N 3.33Å; A57-L60 WeakPolarHBondContact O-CB 3.43Å; A57-L60 PolarHBondContact O-N 3.27Å; A57-L101 HydrophobicContact CB-CB 4.19Å; A57-L101 HydrophobicContact CB-CD1 4.33Å; A57-Y102 HydrophobicContact CB-CE1 4.17Å; A57-I105 HydrophobicContact CB-CD1 3.97Å
58	S	91.3	Very high	90.9	Very high	1 Å²	1	18.5 Å²	18.5	1%	0.007	10%	0.097	C	C	.	.	H	α-helix	trans	-72.4	-30.7	173.9	-63.8	0	0	0	0	113.2	A54 L55 I56 L60 L61 P62 V418 S422	A54-S58 PolarHBondContact O-N 3.43Å; A54-S58 PolarHBondContact O-OG 2.88Å; L55-S58 PolarHBondContact O-N 3.07Å; I56-S58 PolarHBondContact O-N 3.28Å; S58-L60 VanDerWaalsContact C-N 3.25Å; S58-L60 PolarHBondContact O-N 3.08Å; S58-L61 VanDerWaalsContact O-CB 3.31Å; S58-L61 WeakPolarHBondContact O-CB 3.31Å; S58-L61 PolarHBondContact O-N 2.97Å; S58-P62 WeakPolarHBondContact O-CD 3.48Å; S58-V418 WeakPolarHBondContact OG-CG1 3.2Å; S58-V418 PolarHBondContact OG-O 3.44Å; S58-S422 PolarHBondContact OG-OG 3.25Å
59	A	89.6	Confident	90.5	Very high	15 Å²	15	17.7 Å²	17.7	12%	0.124	9%	0.093	C	C	.	.	H	α-helix	trans	-72.3	-18.5	175	0	0	0	0	0	113.2	L18 I22 L55 I56 L61 P62	L18-A59 HydrophobicContact CD2-CB 4.24Å; I22-A59 HydrophobicContact CD1-CB 4.2Å; L55-A59 VanDerWaalsContact O-CB 3.27Å; L55-A59 WeakPolarHBondContact O-CB 3.47Å; L55-A59 PolarHBondContact O-N 2.93Å; I56-A59 PolarHBondContact O-N 3.36Å; A59-L61 VanDerWaalsContact C-N 3.32Å; A59-P62 VanDerWaalsContact O-CD 3.32Å; A59-P62 WeakPolarHBondContact O-CD 3.14Å; A59-P62 WeakPolarHBondContact O-CG 3.16Å
60	L	89.7	Confident	90	Very high	32 Å²	32	18.5 Å²	18.5	17%	0.168	9%	0.094	C	C	.	.	H	α-helix	trans	-70.3	-28.1	171.3	-170	60.1	0	0	0	112	I56 A57 S58 V63 D64 Y98 L101	I56-L60 PolarHBondContact O-N 2.98Å; A57-L60 WeakPolarHBondContact O-CB 3.43Å; A57-L60 PolarHBondContact O-N 3.27Å; S58-L60 VanDerWaalsContact C-N 3.25Å; S58-L60 PolarHBondContact O-N 3.08Å; L60-V63 HydrophobicContact CD1-CB 4.31Å; L60-V63 HydrophobicContact CD1-CG1 4.46Å; L60-V63 CarbonylContact O-C 3.51Å; L60-V63 WeakPolarHBondContact O-CA 3.05Å; L60-V63 WeakPolarHBondContact O-CB 3.4Å; L60-V63 PolarHBondContact O-N 3.13Å; L60-V63 VanDerWaalsContact O-N 3.09Å; L60-D64 PolarHBondContact O-N 3.22Å; L60-Y98 HydrophobicContact CB-CE1 4.1Å; L60-Y98 HydrophobicContact CD2-CD1 3.83Å; L60-Y98 HydrophobicContact CD2-CD2 3.79Å; L60-Y98 HydrophobicContact CD2-CE1 3.69Å; L60-Y98 HydrophobicContact CD2-CE2 3.65Å; L60-Y98 HydrophobicContact CD2-CG 3.84Å; L60-Y98 HydrophobicContact CG-CD2 4.45Å; L60-Y98 HydrophobicContact CG-CE1 4.02Å; L60-Y98 HydrophobicContact CG-CE2 3.82Å; L60-Y98 WeakPolarHBondContact CG-OH 3.26Å; L60-Y98 PolarHBondContact O-OH 3.29Å; L60-L101 HydrophobicContact CD2-CD1 3.91Å
61	L	89.1	Confident	89.5	Confident	1 Å²	1	18.6 Å²	18.6	1%	0.005	10%	0.095	C	C	.	.	H	α-helix	trans	-55	-54.6	179.3	175.6	70.2	0	0	0	113.4	S58 A59 V63 D64 I65 Y98 I425 V433 T477	S58-L61 VanDerWaalsContact O-CB 3.31Å; S58-L61 WeakPolarHBondContact O-CB 3.31Å; S58-L61 PolarHBondContact O-N 2.97Å; A59-L61 VanDerWaalsContact C-N 3.32Å; L61-V63 PolarHBondContact O-N 2.96Å; L61-D64 WeakPolarHBondContact O-CB 3.45Å; L61-D64 PolarHBondContact O-N 2.9Å; L61-I65 HydrophobicContact CD1-CD1 4.28Å; L61-I65 HydrophobicContact CG-CD1 4.18Å; L61-I65 WeakPolarHBondContact O-CG1 3.47Å; L61-I65 PolarHBondContact O-N 3.1Å; L61-I65 VanDerWaalsContact O-N 3.08Å; L61-Y98 VanDerWaalsContact CA-OH 3.25Å; L61-Y98 WeakPolarHBondContact CA-OH 3.44Å; L61-Y98 PolarHBondContact N-OH 3.39Å; L61-Y98 VanDerWaalsContact N-OH 3.08Å; L61-I425 HydrophobicContact CD2-CB 4.13Å; L61-I425 HydrophobicContact CD2-CD1 3.8Å; L61-I425 HydrophobicContact CD2-CG2 3.9Å; L61-V433 HydrophobicContact CD1-CG1 4.13Å; L61-T477 HydrophobicContact CD1-CG2 3.9Å
62	P	87.8	Confident	89.1	Confident	4 Å²	4	19.1 Å²	19.1	3%	0.026	10%	0.097	C	C	.	.	H	α-helix	trans	-67.9	-22.3	178.2	29.6	-38.9	0	0	0	112.9	S58 A59 F66 Y364 I367	S58-P62 WeakPolarHBondContact O-CD 3.48Å; A59-P62 VanDerWaalsContact O-CD 3.32Å; A59-P62 WeakPolarHBondContact O-CD 3.14Å; A59-P62 WeakPolarHBondContact O-CG 3.16Å; P62-F66 WeakPolarHBondContact O-CB 3.09Å; P62-F66 PolarHBondContact O-N 3.29Å; P62-F66 VanDerWaalsContact O-N 3.11Å; P62-Y364 HydrophobicContact CB-CD2 3.44Å; P62-Y364 VanDerWaalsContact CB-CD2 3.44Å; P62-Y364 HydrophobicContact CB-CE2 3.58Å; P62-Y364 HydrophobicContact CB-CG 4.19Å; P62-Y364 HydrophobicContact CG-CD2 3.79Å; P62-Y364 HydrophobicContact CG-CE2 3.38Å; P62-I367 HydrophobicContact CB-CB 4.27Å; P62-I367 HydrophobicContact CB-CD1 4.07Å; P62-I367 HydrophobicContact CB-CG2 4.11Å; P62-I367 HydrophobicContact CG-CG2 4.36Å
63	V	86.8	Confident	88.6	Confident	51 Å²	51	23.9 Å²	23.9	31%	0.309	12%	0.115	S	C	.	.	H	α-helix	trans	-70.9	-42.9	171.5	179.4	0	0	0	0	111.1	L60 L61 F66 L67 Y364	L60-V63 HydrophobicContact CD1-CB 4.31Å; L60-V63 HydrophobicContact CD1-CG1 4.46Å; L60-V63 CarbonylContact O-C 3.51Å; L60-V63 WeakPolarHBondContact O-CA 3.05Å; L60-V63 WeakPolarHBondContact O-CB 3.4Å; L60-V63 PolarHBondContact O-N 3.13Å; L60-V63 VanDerWaalsContact O-N 3.09Å; L61-V63 PolarHBondContact O-N 2.96Å; V63-F66 PolarHBondContact O-N 3.04Å; V63-L67 HydrophobicContact CG1-CD1 3.86Å; V63-L67 HydrophobicContact CG1-CG 4.28Å; V63-L67 WeakPolarHBondContact O-CB 3.28Å; V63-L67 VanDerWaalsContact O-CG 3.31Å; V63-L67 WeakPolarHBondContact O-CG 3.37Å; V63-L67 PolarHBondContact O-N 3.31Å; V63-Y364 HydrophobicContact CG2-CE2 3.8Å
64	D	89.6	Confident	88	Confident	1 Å²	1	30.5 Å²	30.5	1%	0.005	15%	0.145	C	C	.	.	H	α-helix	trans	-58.3	-51.6	175.5	-173.2	11.8	0	0	0	110.5	L60 L61 F66 L67 V68 V94 Y98 T475 R476 T477	L60-D64 PolarHBondContact O-N 3.22Å; L61-D64 WeakPolarHBondContact O-CB 3.45Å; L61-D64 PolarHBondContact O-N 2.9Å; D64-F66 VanDerWaalsContact C-N 3.31Å; D64-F66 PolarHBondContact O-N 3.49Å; D64-L67 PolarHBondContact O-N 3.24Å; D64-V68 VanDerWaalsContact O-CG2 3.32Å; D64-V68 WeakPolarHBondContact O-CG2 3.37Å; D64-V68 PolarHBondContact O-N 2.91Å; D64-V68 VanDerWaalsContact O-N 3.1Å; D64-V94 HydrophobicContact CB-CG1 4.11Å; D64-Y98 HydrophobicContact CB-CE2 4.21Å; D64-T475 WeakPolarHBondContact OD2-CB 3.48Å; D64-R476 PolarHBondContact OD1-N 2.84Å; D64-R476 PolarHBondContact OD2-N 3.34Å; D64-T477 PolarHBondContact OD2-N 2.69Å; D64-T477 PolarHBondContact OD2-OG1 3.41Å
65	I	87.1	Confident	87.5	Confident	1 Å²	1	35.7 Å²	35.7	1%	0.005	17%	0.172	C	C	.	.	H	α-helix	trans	-57.2	-44.4	176.6	-62.6	165.9	0	0	0	111.5	L61 S69 I367 Y432 V433 T475	L61-I65 HydrophobicContact CD1-CD1 4.28Å; L61-I65 HydrophobicContact CG-CD1 4.18Å; L61-I65 WeakPolarHBondContact O-CG1 3.47Å; L61-I65 PolarHBondContact O-N 3.1Å; L61-I65 VanDerWaalsContact O-N 3.08Å; I65-S69 WeakPolarHBondContact O-CB 3.5Å; I65-S69 PolarHBondContact O-N 2.62Å; I65-S69 PolarHBondContact O-OG 2.81Å; I65-I367 HydrophobicContact CD1-CD1 4.03Å; I65-Y432 HydrophobicContact CD1-CE1 4.08Å; I65-Y432 HydrophobicContact CG2-CE1 3.89Å; I65-Y432 HydrophobicContact CG2-CE2 4.49Å; I65-V433 HydrophobicContact CD1-CB 4.4Å; I65-V433 HydrophobicContact CD1-CG1 4.25Å; I65-V433 HydrophobicContact CD1-CG2 4.26Å; I65-T475 HydrophobicContact CG1-CG2 4.05Å
66	F	85.8	Confident	86.9	Confident	54 Å²	54	35.6 Å²	35.6	24%	0.237	17%	0.173	C	C	.	.	H	α-helix	trans	-63.7	-47.9	179.1	170.7	-101	0	0	0	112	P62 V63 D64 V68 S69 Y70 F360	P62-F66 WeakPolarHBondContact O-CB 3.09Å; P62-F66 PolarHBondContact O-N 3.29Å; P62-F66 VanDerWaalsContact O-N 3.11Å; V63-F66 PolarHBondContact O-N 3.04Å; D64-F66 VanDerWaalsContact C-N 3.31Å; D64-F66 PolarHBondContact O-N 3.49Å; F66-V68 VanDerWaalsContact C-N 3.33Å; F66-V68 PolarHBondContact O-N 3.15Å; F66-S69 PolarHBondContact O-N 3.47Å; F66-Y70 HydrophobicContact CE1-CG 4.27Å; F66-Y70 HydrophobicContact CE2-CD2 4.08Å; F66-Y70 HydrophobicContact CE2-CG 4.34Å; F66-Y70 AromaticContact CZ-CD2 3.78Å; F66-Y70 HydrophobicContact CZ-CD2 3.78Å; F66-Y70 HydrophobicContact CZ-CE2 4.44Å; F66-Y70 AromaticContact CZ-CG 3.84Å; F66-Y70 HydrophobicContact CZ-CG 3.84Å; F66-Y70 WeakPolarHBondContact O-CB 3.34Å; F66-Y70 PolarHBondContact O-N 3.43Å; F66-F360 HydrophobicContact CD2-CD2 4.05Å; F66-F360 AromaticContact CD2-CE2 3.58Å; F66-F360 HydrophobicContact CD2-CE2 3.58Å; F66-F360 AromaticContact CE2-CD2 3.65Å; F66-F360 HydrophobicContact CE2-CD2 3.65Å; F66-F360 AromaticContact CE2-CE2 3.23Å; F66-F360 HydrophobicContact CE2-CE2 3.23Å; F66-F360 HydrophobicContact CE2-CZ 4.04Å; F66-F360 HydrophobicContact CG-CE2 4.41Å; F66-F360 AromaticContact CZ-CE2 3.84Å; F66-F360 HydrophobicContact CZ-CE2 3.84Å; F66-F360 HydrophobicContact CZ-CZ 4.2Å
67	L	85.6	Confident	86.6	Confident	45 Å²	45	37 Å²	37	24%	0.236	18%	0.184	C	C	.	.	H	α-helix	trans	-60.6	-45	-177.4	-76.1	170.3	0	0	0	111.2	V63 D64 S69 Y70 M71 I90 V94	V63-L67 HydrophobicContact CG1-CD1 3.86Å; V63-L67 HydrophobicContact CG1-CG 4.28Å; V63-L67 WeakPolarHBondContact O-CB 3.28Å; V63-L67 VanDerWaalsContact O-CG 3.31Å; V63-L67 WeakPolarHBondContact O-CG 3.37Å; V63-L67 PolarHBondContact O-N 3.31Å; D64-L67 PolarHBondContact O-N 3.24Å; L67-S69 VanDerWaalsContact C-N 3.34Å; L67-S69 PolarHBondContact O-N 2.58Å; L67-Y70 PolarHBondContact O-N 3.5Å; L67-M71 WeakPolarHBondContact O-CG 2.9Å; L67-M71 PolarHBondContact O-N 3.39Å; L67-I90 HydrophobicContact CB-CG2 4.35Å; L67-I90 HydrophobicContact CD1-CG2 4.2Å; L67-I90 HydrophobicContact CD2-CG2 4.07Å; L67-I90 HydrophobicContact CG-CG2 4.45Å; L67-V94 HydrophobicContact CD1-CG2 3.33Å
68	V	85.4	Confident	86.2	Confident	4 Å²	4	40.5 Å²	40.5	2%	0.024	20%	0.198	C	C	.	.	H	α-helix	trans	-64.6	-40.1	178.1	-179.1	0	0	0	0	111.1	D64 F66 M71 T473 T475	D64-V68 VanDerWaalsContact O-CG2 3.32Å; D64-V68 WeakPolarHBondContact O-CG2 3.37Å; D64-V68 PolarHBondContact O-N 2.91Å; D64-V68 VanDerWaalsContact O-N 3.1Å; F66-V68 VanDerWaalsContact C-N 3.33Å; F66-V68 PolarHBondContact O-N 3.15Å; V68-M71 HydrophobicContact CB-CE 4.49Å; V68-M71 HydrophobicContact CG2-CE 4.49Å; V68-T473 WeakPolarHBondContact CG1-O 3.33Å; V68-T473 WeakPolarHBondContact CG1-OG1 3.24Å; V68-T475 HydrophobicContact CB-CG2 4.43Å; V68-T475 HydrophobicContact CG2-CG2 4.2Å
69	S	85.3	Confident	86	Confident	7 Å²	7	41.9 Å²	41.9	5%	0.049	20%	0.204	C	C	.	.	H	α-helix	trans	-68.3	-37.5	175	-56.9	0	0	0	0	113.7	I65 F66 L67 M71 K72 Q357 G436 S437	I65-S69 WeakPolarHBondContact O-CB 3.5Å; I65-S69 PolarHBondContact O-N 2.62Å; I65-S69 PolarHBondContact O-OG 2.81Å; F66-S69 PolarHBondContact O-N 3.47Å; L67-S69 VanDerWaalsContact C-N 3.34Å; L67-S69 PolarHBondContact O-N 2.58Å; S69-M71 VanDerWaalsContact C-N 3.29Å; S69-M71 PolarHBondContact O-N 3.06Å; S69-K72 PolarHBondContact O-N 3.25Å; S69-Q357 PolarHBondContact OG-NE2 3.47Å; S69-G436 WeakPolarHBondContact OG-CA 3.39Å; S69-S437 PolarHBondContact OG-N 3.46Å
70	Y	84.9	Confident	85.8	Confident	111 Å²	111	49.8 Å²	49.8	44%	0.435	24%	0.239	S	C	.	.	H	α-helix	trans	-74.6	-18.7	-171	-174.8	-105.4	0	0	0	113.1	F66 L67 K72 K79 W81	F66-Y70 HydrophobicContact CE1-CG 4.27Å; F66-Y70 HydrophobicContact CE2-CD2 4.08Å; F66-Y70 HydrophobicContact CE2-CG 4.34Å; F66-Y70 AromaticContact CZ-CD2 3.78Å; F66-Y70 HydrophobicContact CZ-CD2 3.78Å; F66-Y70 HydrophobicContact CZ-CE2 4.44Å; F66-Y70 AromaticContact CZ-CG 3.84Å; F66-Y70 HydrophobicContact CZ-CG 3.84Å; F66-Y70 WeakPolarHBondContact O-CB 3.34Å; F66-Y70 PolarHBondContact O-N 3.43Å; L67-Y70 PolarHBondContact O-N 3.5Å; Y70-K72 PolarHBondContact O-N 3.27Å; Y70-K79 VanDerWaalsContact CD2-NZ 3.31Å; Y70-K79 VanDerWaalsContact O-CD 3.3Å; Y70-K79 WeakPolarHBondContact O-CD 3.5Å; Y70-K79 WeakPolarHBondContact O-CE 3.5Å; Y70-K79 PolarHBondContact O-NZ 3.48Å; Y70-W81 AromaticContact CD1-CH2 3.87Å; Y70-W81 HydrophobicContact CD1-CH2 3.87Å; Y70-W81 AromaticContact CD1-CZ2 3.44Å; Y70-W81 HydrophobicContact CD1-CZ2 3.44Å; Y70-W81 VanDerWaalsContact CD1-CZ2 3.44Å; Y70-W81 HydrophobicContact CE1-CH2 4.13Å; Y70-W81 AromaticContact CE1-CZ2 3.42Å; Y70-W81 HydrophobicContact CE1-CZ2 3.42Å; Y70-W81 VanDerWaalsContact CE1-CZ2 3.42Å
71	M	84.5	Confident	85.5	Confident	2 Å²	2	53.1 Å²	53.1	1%	0.01	25%	0.249	C	C	.	.	T	Hydrogen-bonded Turn	trans	-68.2	-18	177.6	-72.5	-171.3	-74.1	0	0	113.8	L67 V68 S69 F78 K79 W81 A82 S87 E91	L67-M71 WeakPolarHBondContact O-CG 2.9Å; L67-M71 PolarHBondContact O-N 3.39Å; V68-M71 HydrophobicContact CB-CE 4.49Å; V68-M71 HydrophobicContact CG2-CE 4.49Å; S69-M71 VanDerWaalsContact C-N 3.29Å; S69-M71 PolarHBondContact O-N 3.06Å; M71-F78 HydrophobicContact CB-CD1 4.42Å; M71-K79 PolarHBondContact O-N 3Å; M71-W81 HydrophobicContact CG-CH2 3.97Å; M71-A82 HydrophobicContact CB-CB 4.22Å; M71-A82 HydrophobicContact CG-CB 4.39Å; M71-S87 VanDerWaalsContact SD-CB 3.52Å; M71-E91 HydrophobicContact CE-CG 4.33Å
72	K	85.4	Confident	85.1	Confident	12 Å²	12	53.4 Å²	53.4	5%	0.052	25%	0.251	C	S	.	.	B	Isolated β-bridge	trans	-115	153.5	-176.6	-71.4	-179.8	167.9	-109.3	0	113.4	S69 Y70 G76 T77 F78 K79 Q438 Q471	S69-K72 PolarHBondContact O-N 3.25Å; Y70-K72 PolarHBondContact O-N 3.27Å; K72-G76 PolarHBondContact NZ-O 3.49Å; K72-T77 WeakPolarHBondContact CA-O 3.18Å; K72-F78 HydrophobicContact CD-CE1 4.45Å; K72-F78 HydrophobicContact CG-CD1 3.93Å; K72-F78 HydrophobicContact CG-CE1 4.08Å; K72-F78 HydrophobicContact CG-CG 4.36Å; K72-K79 WeakPolarHBondContact O-CE 3.22Å; K72-Q438 HydrophobicContact CD-CB 4.24Å; K72-Q438 HydrophobicContact CD-CG 4.05Å; K72-Q471 WeakPolarHBondContact CE-O 3.41Å; K72-Q471 PolarHBondContact NZ-O 3.49Å
73	Y	85.1	Confident	84.7	Confident	105 Å²	105	58.6 Å²	58.6	41%	0.412	28%	0.279	S	S	.	.			trans	-79.7	163.4	164.1	-68.4	-69.1	0	0	0	110.6	N75 G76 T77 K79	Y73-N75 PolarHBondContact O-N 3.24Å; Y73-N75 VanDerWaalsContact O-N 3.16Å; Y73-G76 PolarHBondContact O-N 3.36Å; Y73-T77 PolarHBondContact N-O 2.8Å; Y73-K79 HydrophobicContact CD1-CG 4.13Å; Y73-K79 HydrophobicContact CD2-CG 3.97Å; Y73-K79 HydrophobicContact CE1-CD 4.36Å; Y73-K79 HydrophobicContact CE1-CG 3.9Å; Y73-K79 HydrophobicContact CE2-CB 4.07Å; Y73-K79 HydrophobicContact CE2-CG 3.78Å; Y73-K79 HydrophobicContact CG-CG 4.16Å
74	Q	82.4	Confident	84.3	Confident	150 Å²	150	59.4 Å²	59.4	70%	0.701	29%	0.291	S	S	*	.	T	Hydrogen-bonded Turn	trans	-60.2	-24.8	173.2	-71	-174.9	-16.3	0	0	112.8	G76 N439	Q74-G76 PolarHBondContact O-N 2.89Å; Q74-N439 PolarHBondContact O-ND2 3.19Å
75	N	82.3	Confident	83.9	Confident	110 Å²	110	65.3 Å²	65.3	59%	0.588	32%	0.323	S	S	*	.	T	Hydrogen-bonded Turn	trans	-75.1	-2	175.4	-59.8	-4.2	0	0	0	112.9	Y73 T77 L441	Y73-N75 PolarHBondContact O-N 3.24Å; Y73-N75 VanDerWaalsContact O-N 3.16Å; N75-T77 VanDerWaalsContact C-N 3.32Å; N75-T77 PolarHBondContact O-N 3.39Å; N75-L441 WeakPolarHBondContact O-CD2 3.48Å
76	G	81.8	Confident	83.8	Confident	4 Å²	4	67.8 Å²	67.8	4%	0.041	34%	0.337	C	S	.	.	S	Bend	trans	86.1	-8.9	177.3	0	0	0	0	0	116	K72 Y73 Q74 N439	K72-G76 PolarHBondContact NZ-O 3.49Å; Y73-G76 PolarHBondContact O-N 3.36Å; Q74-G76 PolarHBondContact O-N 2.89Å; G76-N439 WeakPolarHBondContact CA-O 3.47Å
77	T	86.4	Confident	83.6	Confident	66 Å²	66	65.8 Å²	65.8	41%	0.405	33%	0.33	S	S	.	.	P	Polyproline II helix	trans	-74.4	146.7	172.3	55.5	0	0	0	0	111.6	K72 Y73 N75 L441	K72-T77 WeakPolarHBondContact CA-O 3.18Å; Y73-T77 PolarHBondContact N-O 2.8Å; N75-T77 VanDerWaalsContact C-N 3.32Å; N75-T77 PolarHBondContact O-N 3.39Å; T77-L441 HydrophobicContact CG2-CD1 3.84Å
78	F	85.1	Confident	83.5	Confident	74 Å²	74	67 Å²	67	33%	0.325	34%	0.339	S	S	.	.	B	Isolated β-bridge	trans	-66.5	146.7	171.3	-74.4	-83.8	0	0	0	110.7	M71 K72	M71-F78 HydrophobicContact CB-CD1 4.42Å; K72-F78 HydrophobicContact CD-CE1 4.45Å; K72-F78 HydrophobicContact CG-CD1 3.93Å; K72-F78 HydrophobicContact CG-CE1 4.08Å; K72-F78 HydrophobicContact CG-CG 4.36Å
79	K	86.4	Confident	83.6	Confident	30 Å²	30	72.6 Å²	72.6	13%	0.13	37%	0.365	C	S	.	.	P	Polyproline II helix	trans	-68.4	150.2	173.8	-65.3	-175.6	-179.3	164.4	0	110.6	Y70 M71 K72 Y73 W81 A82	Y70-K79 VanDerWaalsContact CD2-NZ 3.31Å; Y70-K79 VanDerWaalsContact O-CD 3.3Å; Y70-K79 WeakPolarHBondContact O-CD 3.5Å; Y70-K79 WeakPolarHBondContact O-CE 3.5Å; Y70-K79 PolarHBondContact O-NZ 3.48Å; M71-K79 PolarHBondContact O-N 3Å; K72-K79 WeakPolarHBondContact O-CE 3.22Å; Y73-K79 HydrophobicContact CD1-CG 4.13Å; Y73-K79 HydrophobicContact CD2-CG 3.97Å; Y73-K79 HydrophobicContact CE1-CD 4.36Å; Y73-K79 HydrophobicContact CE1-CG 3.9Å; Y73-K79 HydrophobicContact CE2-CB 4.07Å; Y73-K79 HydrophobicContact CE2-CG 3.78Å; Y73-K79 HydrophobicContact CG-CG 4.16Å; K79-W81 HydrophobicContact CB-CG 4.39Å; K79-W81 HydrophobicContact CD-CZ2 4.03Å; K79-W81 PolarHBondContact O-N 2.71Å; K79-W81 VanDerWaalsContact O-N 3.15Å; K79-A82 HydrophobicContact CB-CB 4.3Å; K79-A82 WeakPolarHBondContact O-CA 3.18Å; K79-A82 WeakPolarHBondContact O-CB 3.4Å; K79-A82 PolarHBondContact O-N 2.8Å
80	E	85.5	Confident	83.6	Confident	181 Å²	181	74.2 Å²	74.2	85%	0.846	37%	0.373	S	S	*	.	T	Hydrogen-bonded Turn	trans	-58.5	-32.7	-176.5	-63	-177.6	172.5	0	0	113.4	A82	E80-A82 VanDerWaalsContact C-N 3.35Å
81	W	83.2	Confident	83.5	Confident	103 Å²	103	69.9 Å²	69.9	39%	0.39	36%	0.357	S	S	.	.	T	Hydrogen-bonded Turn	trans	-76.3	-22.8	175.6	65.6	-98.7	0	0	0	113	Y70 M71 K79 N83 V86 I90	Y70-W81 AromaticContact CD1-CH2 3.87Å; Y70-W81 HydrophobicContact CD1-CH2 3.87Å; Y70-W81 AromaticContact CD1-CZ2 3.44Å; Y70-W81 HydrophobicContact CD1-CZ2 3.44Å; Y70-W81 VanDerWaalsContact CD1-CZ2 3.44Å; Y70-W81 HydrophobicContact CE1-CH2 4.13Å; Y70-W81 AromaticContact CE1-CZ2 3.42Å; Y70-W81 HydrophobicContact CE1-CZ2 3.42Å; Y70-W81 VanDerWaalsContact CE1-CZ2 3.42Å; M71-W81 HydrophobicContact CG-CH2 3.97Å; K79-W81 HydrophobicContact CB-CG 4.39Å; K79-W81 HydrophobicContact CD-CZ2 4.03Å; K79-W81 PolarHBondContact O-N 2.71Å; K79-W81 VanDerWaalsContact O-N 3.15Å; W81-N83 PolarHBondContact O-N 3.21Å; W81-V86 HydrophobicContact CE3-CG1 4.43Å; W81-I90 HydrophobicContact CH2-CD1 4.33Å; W81-I90 HydrophobicContact CZ3-CD1 3.7Å
82	A	81.4	Confident	83.6	Confident	6 Å²	6	72.6 Å²	72.6	5%	0.05	37%	0.371	C	S	.	.			trans	-86.8	52.7	-179.1	0	0	0	0	0	110.5	M71 K79 E80	M71-A82 HydrophobicContact CB-CB 4.22Å; M71-A82 HydrophobicContact CG-CB 4.39Å; K79-A82 HydrophobicContact CB-CB 4.3Å; K79-A82 WeakPolarHBondContact O-CA 3.18Å; K79-A82 WeakPolarHBondContact O-CB 3.4Å; K79-A82 PolarHBondContact O-N 2.8Å; E80-A82 VanDerWaalsContact C-N 3.35Å
83	N	78.6	Confident	83.8	Confident	113 Å²	113	76.3 Å²	76.3	60%	0.604	40%	0.395	S	S	*	.			trans	-63.5	154.1	170.9	-166.2	5.2	0	0	0	109.9	W81 N85 V86 S87	W81-N83 PolarHBondContact O-N 3.21Å; N83-N85 PolarHBondContact O-N 3.45Å; N83-V86 PolarHBondContact O-N 3.34Å; N83-S87 PolarHBondContact O-N 3.02Å; N83-S87 VanDerWaalsContact O-N 3.08Å; N83-S87 PolarHBondContact O-OG 2.84Å
84	A	78	Confident	84	Confident	68 Å²	68	71.9 Å²	71.9	56%	0.562	38%	0.379	S	S	*	.	H	α-helix	trans	-52.6	-34.1	-171.7	0	0	0	0	0	114	S87 V88	A84-S87 WeakPolarHBondContact CA-OG 3.45Å; A84-S87 PolarHBondContact O-OG 3.3Å; A84-V88 VanDerWaalsContact O-CG2 3.22Å; A84-V88 WeakPolarHBondContact O-CG2 3.5Å; A84-V88 PolarHBondContact O-N 3.23Å
85	N	82.8	Confident	84.2	Confident	126 Å²	126	66.1 Å²	66.1	67%	0.674	35%	0.353	S	S	*	.	H	α-helix	trans	-71.6	-36.2	177.3	-168	46.6	0	0	0	113	N83 Q89	N83-N85 PolarHBondContact O-N 3.45Å; N85-Q89 WeakPolarHBondContact O-CB 3.46Å; N85-Q89 PolarHBondContact O-N 2.86Å
86	V	84.5	Confident	84.5	Confident	52 Å²	52	68.3 Å²	68.3	32%	0.315	35%	0.354	S	S	.	.	H	α-helix	trans	-76.5	-40.3	-178	-179.6	0	0	0	0	110.7	W81 N83 Q89 I90	W81-V86 HydrophobicContact CE3-CG1 4.43Å; N83-V86 PolarHBondContact O-N 3.34Å; V86-Q89 PolarHBondContact O-N 3.26Å; V86-I90 HydrophobicContact CG1-CD1 4.1Å; V86-I90 WeakPolarHBondContact O-CG1 3.3Å; V86-I90 PolarHBondContact O-N 3.46Å
87	S	82.1	Confident	84.9	Confident	13 Å²	13	69.3 Å²	69.3	9%	0.091	36%	0.364	C	S	.	.	H	α-helix	trans	-59.7	-48	175.4	53.1	0	0	0	0	111.4	M71 N83 A84 Q89 I90 E91	M71-S87 VanDerWaalsContact SD-CB 3.52Å; N83-S87 PolarHBondContact O-N 3.02Å; N83-S87 VanDerWaalsContact O-N 3.08Å; N83-S87 PolarHBondContact O-OG 2.84Å; A84-S87 WeakPolarHBondContact CA-OG 3.45Å; A84-S87 PolarHBondContact O-OG 3.3Å; S87-Q89 VanDerWaalsContact C-N 3.29Å; S87-Q89 PolarHBondContact O-N 2.88Å; S87-I90 PolarHBondContact O-N 3.25Å; S87-E91 WeakPolarHBondContact O-CB 3.25Å; S87-E91 VanDerWaalsContact O-CG 3.28Å; S87-E91 WeakPolarHBondContact O-CG 3.38Å; S87-E91 PolarHBondContact O-N 3.45Å
88	V	83.5	Confident	85.1	Confident	69 Å²	69	66.2 Å²	66.2	42%	0.418	35%	0.345	S	S	.	.	H	α-helix	trans	-59.3	-39.6	175.6	171.5	0	0	0	0	111.5	A84 E91 N92	A84-V88 VanDerWaalsContact O-CG2 3.22Å; A84-V88 WeakPolarHBondContact O-CG2 3.5Å; A84-V88 PolarHBondContact O-N 3.23Å; V88-E91 PolarHBondContact O-N 3.41Å; V88-N92 WeakPolarHBondContact CG1-ND2 3.47Å; V88-N92 VanDerWaalsContact O-CB 3.3Å; V88-N92 WeakPolarHBondContact O-CB 3.49Å; V88-N92 PolarHBondContact O-N 2.7Å; V88-N92 PolarHBondContact O-ND2 3.4Å
89	Q	86.1	Confident	85.4	Confident	122 Å²	122	67.4 Å²	67.4	57%	0.57	35%	0.348	S	S	*	.	H	α-helix	trans	-65.5	-42.1	177.6	-170.5	-179.4	-11.5	0	0	112.6	N85 V86 S87 T93	N85-Q89 WeakPolarHBondContact O-CB 3.46Å; N85-Q89 PolarHBondContact O-N 2.86Å; V86-Q89 PolarHBondContact O-N 3.26Å; S87-Q89 VanDerWaalsContact C-N 3.29Å; S87-Q89 PolarHBondContact O-N 2.88Å; Q89-T93 WeakPolarHBondContact O-CB 3.23Å; Q89-T93 PolarHBondContact O-N 2.96Å; Q89-T93 PolarHBondContact O-OG1 3.44Å
90	I	84.8	Confident	85.7	Confident	42 Å²	42	69.9 Å²	69.9	22%	0.215	37%	0.366	C	S	.	.	H	α-helix	trans	-64	-47.5	176.4	-69.7	169.7	0	0	0	110	L67 W81 V86 S87 N92 T93 V94	L67-I90 HydrophobicContact CB-CG2 4.35Å; L67-I90 HydrophobicContact CD1-CG2 4.2Å; L67-I90 HydrophobicContact CD2-CG2 4.07Å; L67-I90 HydrophobicContact CG-CG2 4.45Å; W81-I90 HydrophobicContact CH2-CD1 4.33Å; W81-I90 HydrophobicContact CZ3-CD1 3.7Å; V86-I90 HydrophobicContact CG1-CD1 4.1Å; V86-I90 WeakPolarHBondContact O-CG1 3.3Å; V86-I90 PolarHBondContact O-N 3.46Å; S87-I90 PolarHBondContact O-N 3.25Å; I90-N92 PolarHBondContact O-N 3.09Å; I90-T93 WeakPolarHBondContact O-CB 3.42Å; I90-T93 PolarHBondContact O-N 3.34Å; I90-T93 VanDerWaalsContact O-N 3.1Å; I90-V94 PolarHBondContact O-N 2.87Å
91	E	84.4	Confident	86.1	Confident	20 Å²	20	62.8 Å²	62.8	9%	0.093	33%	0.333	C	S	.	.	H	α-helix	trans	-60.4	-43.4	178.8	-74.3	172	-163.2	0	0	112.2	M71 S87 V88 T93 V94 L95 R476	M71-E91 HydrophobicContact CE-CG 4.33Å; S87-E91 WeakPolarHBondContact O-CB 3.25Å; S87-E91 VanDerWaalsContact O-CG 3.28Å; S87-E91 WeakPolarHBondContact O-CG 3.38Å; S87-E91 PolarHBondContact O-N 3.45Å; V88-E91 PolarHBondContact O-N 3.41Å; E91-T93 VanDerWaalsContact C-N 3.31Å; E91-T93 PolarHBondContact O-N 2.89Å; E91-V94 PolarHBondContact O-N 2.76Å; E91-L95 WeakPolarHBondContact O-CB 3.29Å; E91-L95 PolarHBondContact O-N 3.32Å; E91-R476 IonicContact OE2-CZ 3.83Å; E91-R476 IonicContact OE2-NH2 3.69Å; E91-R476 PolarHBondContact OE2-NH2 3.09Å
92	N	85.7	Confident	86.6	Confident	58 Å²	58	58 Å²	58	31%	0.31	32%	0.315	S	S	.	.	H	α-helix	trans	-64.6	-35.2	174.5	-76.1	-26.8	0	0	0	112.3	V88 I90 L95 Y96	V88-N92 WeakPolarHBondContact CG1-ND2 3.47Å; V88-N92 VanDerWaalsContact O-CB 3.3Å; V88-N92 WeakPolarHBondContact O-CB 3.49Å; V88-N92 PolarHBondContact O-N 2.7Å; V88-N92 PolarHBondContact O-ND2 3.4Å; I90-N92 PolarHBondContact O-N 3.09Å; N92-L95 WeakPolarHBondContact O-CB 3.37Å; N92-L95 PolarHBondContact O-N 3.26Å; N92-Y96 HydrophobicContact CB-CE2 4.31Å; N92-Y96 WeakPolarHBondContact O-CD2 3.49Å; N92-Y96 PolarHBondContact O-N 3.37Å
93	T	89.3	Confident	87.2	Confident	91 Å²	91	59.7 Å²	59.7	56%	0.558	33%	0.327	S	S	*	.	H	α-helix	trans	-63.6	-45.1	176.4	-57.8	0	0	0	0	111	Q89 I90 E91 Y96 G97	Q89-T93 WeakPolarHBondContact O-CB 3.23Å; Q89-T93 PolarHBondContact O-N 2.96Å; Q89-T93 PolarHBondContact O-OG1 3.44Å; I90-T93 WeakPolarHBondContact O-CB 3.42Å; I90-T93 PolarHBondContact O-N 3.34Å; I90-T93 VanDerWaalsContact O-N 3.1Å; E91-T93 VanDerWaalsContact C-N 3.31Å; E91-T93 PolarHBondContact O-N 2.89Å; T93-Y96 PolarHBondContact O-N 3.3Å; T93-G97 PolarHBondContact O-N 3.4Å
94	V	88.9	Confident	88	Confident	11 Å²	11	56.4 Å²	56.4	7%	0.067	31%	0.311	C	S	.	.	H	α-helix	trans	-64.3	-42.4	175.3	178	0	0	0	0	110.8	D64 L67 I90 E91 Y96 G97 Y98 R476	D64-V94 HydrophobicContact CB-CG1 4.11Å; L67-V94 HydrophobicContact CD1-CG2 3.33Å; I90-V94 PolarHBondContact O-N 2.87Å; E91-V94 PolarHBondContact O-N 2.76Å; V94-Y96 PolarHBondContact O-N 3.11Å; V94-G97 WeakPolarHBondContact O-CA 3.38Å; V94-G97 PolarHBondContact O-N 2.97Å; V94-G97 VanDerWaalsContact O-N 3.11Å; V94-Y98 HydrophobicContact CG1-CD2 3.87Å; V94-Y98 HydrophobicContact CG1-CE2 3.61Å; V94-Y98 WeakPolarHBondContact O-CD2 3.36Å; V94-Y98 PolarHBondContact O-N 3.47Å; V94-R476 HydrophobicContact CG1-CB 4.3Å; V94-R476 HydrophobicContact CG1-CG 4.42Å
95	L	87.5	Confident	88.8	Confident	30 Å²	30	53.2 Å²	53.2	16%	0.157	28%	0.284	C	S	.	.	H	α-helix	trans	-57.3	-47.6	176.5	-177	65.6	0	0	0	112	E91 N92 G97 Y98 Y99 L187 F480	E91-L95 WeakPolarHBondContact O-CB 3.29Å; E91-L95 PolarHBondContact O-N 3.32Å; N92-L95 WeakPolarHBondContact O-CB 3.37Å; N92-L95 PolarHBondContact O-N 3.26Å; L95-G97 VanDerWaalsContact C-N 3.3Å; L95-G97 PolarHBondContact O-N 2.87Å; L95-Y98 PolarHBondContact O-N 2.84Å; L95-Y99 WeakPolarHBondContact O-CB 3.37Å; L95-Y99 PolarHBondContact O-N 3.49Å; L95-L187 HydrophobicContact CD1-CD1 3.8Å; L95-F480 HydrophobicContact CD1-CE2 3.59Å; L95-F480 HydrophobicContact CD1-CZ 3.7Å
96	Y	88.4	Confident	89.4	Confident	156 Å²	156	47.7 Å²	47.7	61%	0.612	26%	0.255	S	S	*	.	H	α-helix	trans	-66	-32.4	175.5	-68.8	-47.5	0	0	0	112.7	N92 T93 V94 Y99 T100	N92-Y96 HydrophobicContact CB-CE2 4.31Å; N92-Y96 WeakPolarHBondContact O-CD2 3.49Å; N92-Y96 PolarHBondContact O-N 3.37Å; T93-Y96 PolarHBondContact O-N 3.3Å; V94-Y96 PolarHBondContact O-N 3.11Å; Y96-Y99 PolarHBondContact O-N 3.37Å; Y96-T100 WeakPolarHBondContact O-CB 3.42Å; Y96-T100 PolarHBondContact O-N 2.83Å; Y96-T100 PolarHBondContact O-OG1 3.15Å
97	G	90.8	Very high	90	Very high	24 Å²	24	50 Å²	50	25%	0.247	26%	0.261	C	S	.	.	H	α-helix	trans	-58.1	-52.2	170.8	0	0	0	0	0	111.9	T93 V94 L95 T100 L101	T93-G97 PolarHBondContact O-N 3.4Å; V94-G97 WeakPolarHBondContact O-CA 3.38Å; V94-G97 PolarHBondContact O-N 2.97Å; V94-G97 VanDerWaalsContact O-N 3.11Å; L95-G97 VanDerWaalsContact C-N 3.3Å; L95-G97 PolarHBondContact O-N 2.87Å; G97-T100 PolarHBondContact O-N 2.73Å; G97-L101 WeakPolarHBondContact O-CB 3.43Å; G97-L101 WeakPolarHBondContact O-CG 3.44Å; G97-L101 PolarHBondContact O-N 3.23Å
98	Y	91.4	Very high	90.6	Very high	1 Å²	1	49.4 Å²	49.4	0%	0.004	26%	0.257	C	S	.	.	H	α-helix	trans	-61	-45.5	174.6	-80.6	-65.2	0	0	0	112.3	L60 L61 D64 V94 L95 T100 L101 Y102 R476 T477 F480	L60-Y98 HydrophobicContact CB-CE1 4.1Å; L60-Y98 HydrophobicContact CD2-CD1 3.83Å; L60-Y98 HydrophobicContact CD2-CD2 3.79Å; L60-Y98 HydrophobicContact CD2-CE1 3.69Å; L60-Y98 HydrophobicContact CD2-CE2 3.65Å; L60-Y98 HydrophobicContact CD2-CG 3.84Å; L60-Y98 HydrophobicContact CG-CD2 4.45Å; L60-Y98 HydrophobicContact CG-CE1 4.02Å; L60-Y98 HydrophobicContact CG-CE2 3.82Å; L60-Y98 WeakPolarHBondContact CG-OH 3.26Å; L60-Y98 PolarHBondContact O-OH 3.29Å; L61-Y98 VanDerWaalsContact CA-OH 3.25Å; L61-Y98 WeakPolarHBondContact CA-OH 3.44Å; L61-Y98 PolarHBondContact N-OH 3.39Å; L61-Y98 VanDerWaalsContact N-OH 3.08Å; D64-Y98 HydrophobicContact CB-CE2 4.21Å; V94-Y98 HydrophobicContact CG1-CD2 3.87Å; V94-Y98 HydrophobicContact CG1-CE2 3.61Å; V94-Y98 WeakPolarHBondContact O-CD2 3.36Å; V94-Y98 PolarHBondContact O-N 3.47Å; L95-Y98 PolarHBondContact O-N 2.84Å; Y98-T100 VanDerWaalsContact C-N 3.29Å; Y98-T100 PolarHBondContact O-N 3.21Å; Y98-L101 PolarHBondContact O-N 3.47Å; Y98-Y102 HydrophobicContact CD1-CD2 4.45Å; Y98-Y102 HydrophobicContact CD1-CE1 4.19Å; Y98-Y102 AromaticContact CD1-CE2 3.78Å; Y98-Y102 HydrophobicContact CD1-CE2 3.78Å; Y98-Y102 AromaticContact CD1-CZ 3.65Å; Y98-Y102 HydrophobicContact CG-CE2 4.39Å; Y98-Y102 WeakPolarHBondContact O-CB 3.25Å; Y98-Y102 PolarHBondContact O-N 2.93Å; Y98-R476 HydrophobicContact CD2-CB 4.33Å; Y98-T477 WeakPolarHBondContact CE2-OG1 3.42Å; Y98-T477 PolarHBondContact OH-OG1 3.43Å; Y98-F480 HydrophobicContact CG-CD2 4.41Å; Y98-F480 HydrophobicContact CG-CE2 4.21Å
99	Y	90.4	Very high	91.2	Very high	99 Å²	99	46.3 Å²	46.3	39%	0.388	24%	0.238	S	C	.	.	H	α-helix	trans	-56	-45.4	178.7	-170.2	-91.4	0	0	0	111.7	L95 Y96 S103 L190	L95-Y99 WeakPolarHBondContact O-CB 3.37Å; L95-Y99 PolarHBondContact O-N 3.49Å; Y96-Y99 PolarHBondContact O-N 3.37Å; Y99-S103 WeakPolarHBondContact O-CB 3.2Å; Y99-S103 PolarHBondContact O-N 3.46Å; Y99-S103 PolarHBondContact O-OG 3.44Å; Y99-L190 HydrophobicContact CD2-CD1 3.94Å; Y99-L190 HydrophobicContact CE2-CD1 3.96Å; Y99-L190 HydrophobicContact CG-CD1 4.41Å
100	T	92.1	Very high	91.7	Very high	83 Å²	83	41.4 Å²	41.4	51%	0.509	21%	0.214	S	C	.	.	H	α-helix	trans	-66.5	-52.1	179.2	-55.4	0	0	0	0	111	Y96 G97 Y98 Y102 S103 V104	Y96-T100 WeakPolarHBondContact O-CB 3.42Å; Y96-T100 PolarHBondContact O-N 2.83Å; Y96-T100 PolarHBondContact O-OG1 3.15Å; G97-T100 PolarHBondContact O-N 2.73Å; Y98-T100 VanDerWaalsContact C-N 3.29Å; Y98-T100 PolarHBondContact O-N 3.21Å; T100-Y102 PolarHBondContact O-N 3.4Å; T100-S103 PolarHBondContact O-N 3.39Å; T100-V104 VanDerWaalsContact O-CG2 3.31Å; T100-V104 WeakPolarHBondContact O-CG2 3.39Å; T100-V104 PolarHBondContact O-N 3.06Å
101	L	94.1	Very high	92.2	Very high	32 Å²	32	42.4 Å²	42.4	17%	0.168	22%	0.217	C	C	.	.	H	α-helix	trans	-62.9	-45	-177.3	-69.6	169.5	0	0	0	111.7	V53 I56 A57 L60 G97 Y98 V104 I105	V53-L101 HydrophobicContact CG1-CD2 4.45Å; I56-L101 HydrophobicContact CB-CD2 4.42Å; I56-L101 HydrophobicContact CG2-CD1 3.99Å; I56-L101 HydrophobicContact CG2-CD2 3.77Å; A57-L101 HydrophobicContact CB-CB 4.19Å; A57-L101 HydrophobicContact CB-CD1 4.33Å; L60-L101 HydrophobicContact CD2-CD1 3.91Å; G97-L101 WeakPolarHBondContact O-CB 3.43Å; G97-L101 WeakPolarHBondContact O-CG 3.44Å; G97-L101 PolarHBondContact O-N 3.23Å; Y98-L101 PolarHBondContact O-N 3.47Å; L101-V104 PolarHBondContact O-N 3.39Å; L101-I105 WeakPolarHBondContact O-CG1 3.43Å; L101-I105 PolarHBondContact O-N 3Å
102	Y	93.6	Very high	92.7	Very high	1 Å²	1	45.1 Å²	45.1	0%	0.004	23%	0.227	C	C	.	.	H	α-helix	trans	-68.4	-34.5	178.1	-71.2	-13.9	0	0	0	113	A57 Y98 T100 V104 I105 L106 L190 I194 L419 F480	A57-Y102 HydrophobicContact CB-CE1 4.17Å; Y98-Y102 HydrophobicContact CD1-CD2 4.45Å; Y98-Y102 HydrophobicContact CD1-CE1 4.19Å; Y98-Y102 AromaticContact CD1-CE2 3.78Å; Y98-Y102 HydrophobicContact CD1-CE2 3.78Å; Y98-Y102 AromaticContact CD1-CZ 3.65Å; Y98-Y102 HydrophobicContact CG-CE2 4.39Å; Y98-Y102 WeakPolarHBondContact O-CB 3.25Å; Y98-Y102 PolarHBondContact O-N 2.93Å; T100-Y102 PolarHBondContact O-N 3.4Å; Y102-V104 VanDerWaalsContact C-N 3.35Å; Y102-I105 HydrophobicContact CD1-CD1 4.01Å; Y102-I105 HydrophobicContact CE1-CD1 4.5Å; Y102-I105 PolarHBondContact O-N 3.22Å; Y102-L106 WeakPolarHBondContact O-CG 3.3Å; Y102-L106 PolarHBondContact O-N 2.99Å; Y102-L190 HydrophobicContact CD2-CD2 3.95Å; Y102-L190 HydrophobicContact CG-CD2 4.37Å; Y102-I194 HydrophobicContact CD1-CD1 4.29Å; Y102-I194 HydrophobicContact CD2-CG1 4.06Å; Y102-I194 HydrophobicContact CD2-CG2 4.31Å; Y102-I194 HydrophobicContact CE2-CG2 4.27Å; Y102-I194 HydrophobicContact CG-CD1 3.97Å; Y102-I194 HydrophobicContact CG-CG1 3.94Å; Y102-L419 HydrophobicContact CD1-CD1 4.23Å; Y102-L419 HydrophobicContact CE1-CD1 3.77Å; Y102-F480 HydrophobicContact CD2-CD1 4.35Å; Y102-F480 HydrophobicContact CD2-CG 4.37Å; Y102-F480 HydrophobicContact CE2-CB 4.13Å; Y102-F480 HydrophobicContact CE2-CD1 4.48Å; Y102-F480 HydrophobicContact CE2-CD2 4.27Å; Y102-F480 HydrophobicContact CE2-CG 4.06Å
103	S	93.4	Very high	93.1	Very high	43 Å²	43	42.7 Å²	42.7	30%	0.301	21%	0.214	S	C	.	.	H	α-helix	trans	-63.4	-41.9	171.2	-63.3	0	0	0	0	111.6	Y99 T100 I105 L106 F107 L190	Y99-S103 WeakPolarHBondContact O-CB 3.2Å; Y99-S103 PolarHBondContact O-N 3.46Å; Y99-S103 PolarHBondContact O-OG 3.44Å; T100-S103 PolarHBondContact O-N 3.39Å; S103-I105 VanDerWaalsContact C-N 3.34Å; S103-L106 PolarHBondContact O-N 2.88Å; S103-F107 WeakPolarHBondContact O-CB 3.21Å; S103-F107 PolarHBondContact O-N 3.24Å; S103-L190 VanDerWaalsContact OG-CD1 3.22Å; S103-L190 WeakPolarHBondContact OG-CD1 3.04Å
104	V	96.2	Very high	93.4	Very high	43 Å²	43	38.8 Å²	38.8	26%	0.261	19%	0.19	S	C	.	.	H	α-helix	trans	-65.1	-38.3	174.6	177.6	0	0	0	0	110.9	F49 V53 T100 L101 Y102 F107 C108	F49-V104 HydrophobicContact CE1-CG1 4.06Å; F49-V104 HydrophobicContact CZ-CG1 3.88Å; V53-V104 HydrophobicContact CB-CG1 4.46Å; V53-V104 HydrophobicContact CG1-CB 4.16Å; V53-V104 HydrophobicContact CG1-CG1 3.84Å; V53-V104 HydrophobicContact CG2-CG1 3.9Å; T100-V104 VanDerWaalsContact O-CG2 3.31Å; T100-V104 WeakPolarHBondContact O-CG2 3.39Å; T100-V104 PolarHBondContact O-N 3.06Å; L101-V104 PolarHBondContact O-N 3.39Å; Y102-V104 VanDerWaalsContact C-N 3.35Å; V104-F107 PolarHBondContact O-N 3.12Å; V104-C108 WeakPolarHBondContact O-CB 3.49Å; V104-C108 PolarHBondContact O-N 3.19Å; V104-C108 PolarHBondContact O-SG 3.21Å
105	I	95.7	Very high	93.7	Very high	1 Å²	1	40 Å²	40	1%	0.005	19%	0.194	C	C	.	.	H	α-helix	trans	-61.1	-46.7	173.7	-70.6	175.9	0	0	0	111.1	V53 A57 L101 Y102 S103 F107 C108 V109 L197 L415 L419	V53-I105 HydrophobicContact CG1-CG1 3.73Å; A57-I105 HydrophobicContact CB-CD1 3.97Å; L101-I105 WeakPolarHBondContact O-CG1 3.43Å; L101-I105 PolarHBondContact O-N 3Å; Y102-I105 HydrophobicContact CD1-CD1 4.01Å; Y102-I105 HydrophobicContact CE1-CD1 4.5Å; Y102-I105 PolarHBondContact O-N 3.22Å; S103-I105 VanDerWaalsContact C-N 3.34Å; I105-F107 VanDerWaalsContact C-N 3.33Å; I105-F107 PolarHBondContact O-N 2.83Å; I105-C108 WeakPolarHBondContact O-CB 3.37Å; I105-C108 PolarHBondContact O-N 3.45Å; I105-V109 HydrophobicContact CG2-CG2 4.3Å; I105-V109 WeakPolarHBondContact O-CG2 3.41Å; I105-V109 PolarHBondContact O-N 3.47Å; I105-L197 HydrophobicContact CG2-CD1 4.47Å; I105-L415 HydrophobicContact CG2-CD1 4.48Å; I105-L415 HydrophobicContact CG2-CD2 3.91Å; I105-L419 HydrophobicContact CD1-CD1 4.08Å
106	L	95.3	Very high	94	Very high	10 Å²	10	38.6 Å²	38.6	5%	0.052	19%	0.187	C	C	.	.	H	α-helix	trans	-60.2	-44.1	176.6	-73.4	173.5	0	0	0	111.5	Y102 S103 C108 V109 F110 L152 L190 I194 L197	Y102-L106 WeakPolarHBondContact O-CG 3.3Å; Y102-L106 PolarHBondContact O-N 2.99Å; S103-L106 PolarHBondContact O-N 2.88Å; L106-C108 PolarHBondContact O-N 3.48Å; L106-V109 PolarHBondContact O-N 2.95Å; L106-F110 HydrophobicContact CD2-CD2 3.96Å; L106-F110 HydrophobicContact CD2-CE2 3.68Å; L106-F110 WeakPolarHBondContact O-CB 3.19Å; L106-F110 WeakPolarHBondContact O-CD2 3.37Å; L106-F110 PolarHBondContact O-N 3.42Å; L106-L152 HydrophobicContact CD1-CD2 4.34Å; L106-L190 HydrophobicContact CD1-CG 4.34Å; L106-I194 HydrophobicContact CD2-CD1 4.24Å; L106-I194 HydrophobicContact CG-CD1 4.03Å; L106-L197 HydrophobicContact CD2-CD1 3.65Å; L106-L197 HydrophobicContact CD2-CG 4.45Å
107	F	95.7	Very high	94.1	Very high	102 Å²	102	33.1 Å²	33.1	45%	0.447	17%	0.166	S	C	.	.	H	α-helix	trans	-60	-44.7	174.3	175.1	-98	0	0	0	111.9	S103 V104 I105 F111 W112	S103-F107 WeakPolarHBondContact O-CB 3.21Å; S103-F107 PolarHBondContact O-N 3.24Å; V104-F107 PolarHBondContact O-N 3.12Å; I105-F107 VanDerWaalsContact C-N 3.33Å; I105-F107 PolarHBondContact O-N 2.83Å; F107-F111 HydrophobicContact CD2-CB 4.1Å; F107-F111 HydrophobicContact CD2-CD1 4Å; F107-F111 HydrophobicContact CD2-CG 4.32Å; F107-F111 HydrophobicContact CE1-CD1 4.34Å; F107-F111 HydrophobicContact CE2-CB 4.16Å; F107-F111 AromaticContact CE2-CD1 3.2Å; F107-F111 HydrophobicContact CE2-CD1 3.2Å; F107-F111 AromaticContact CE2-CE1 3.78Å; F107-F111 HydrophobicContact CE2-CE1 3.78Å; F107-F111 AromaticContact CE2-CG 3.89Å; F107-F111 HydrophobicContact CE2-CG 3.89Å; F107-F111 AromaticContact CZ-CD1 3.41Å; F107-F111 HydrophobicContact CZ-CD1 3.41Å; F107-F111 VanDerWaalsContact CZ-CD1 3.41Å; F107-F111 AromaticContact CZ-CE1 3.83Å; F107-F111 HydrophobicContact CZ-CE1 3.83Å; F107-F111 HydrophobicContact CZ-CG 4.46Å; F107-F111 WeakPolarHBondContact O-CA 3.48Å; F107-F111 WeakPolarHBondContact O-CB 3.38Å; F107-F111 PolarHBondContact O-N 3.26Å; F107-W112 HydrophobicContact CD1-CB 4.21Å; F107-W112 HydrophobicContact CE1-CB 3.82Å; F107-W112 HydrophobicContact CE1-CE3 4.48Å; F107-W112 HydrophobicContact CE1-CG 4.29Å; F107-W112 HydrophobicContact CZ-CB 4.39Å; F107-W112 HydrophobicContact CZ-CE3 4.42Å; F107-W112 PolarHBondContact O-N 3.03Å
108	C	96.1	Very high	94.1	Very high	0 Å²	0	34.2 Å²	34.2	0%	0	16%	0.164	C	C	.	.	I	π-helix	trans	-59.9	-48.3	176.8	-76.5	0	0	0	0	112	V104 I105 L106 I113	V104-C108 WeakPolarHBondContact O-CB 3.49Å; V104-C108 PolarHBondContact O-N 3.19Å; V104-C108 PolarHBondContact O-SG 3.21Å; I105-C108 WeakPolarHBondContact O-CB 3.37Å; I105-C108 PolarHBondContact O-N 3.45Å; L106-C108 PolarHBondContact O-N 3.48Å; C108-I113 VanDerWaalsContact O-CB 3.27Å; C108-I113 WeakPolarHBondContact O-CB 3.37Å; C108-I113 VanDerWaalsContact O-CG1 3.25Å; C108-I113 WeakPolarHBondContact O-CG1 3.41Å; C108-I113 PolarHBondContact O-N 3.03Å
109	V	95.9	Very high	94	Very high	4 Å²	4	36.8 Å²	36.8	2%	0.024	17%	0.174	C	C	.	.	I	π-helix	trans	-73.4	-42.2	-174.3	172.5	0	0	0	0	112.5	I105 L106 P114 L197 M412 L415	I105-V109 HydrophobicContact CG2-CG2 4.3Å; I105-V109 WeakPolarHBondContact O-CG2 3.41Å; I105-V109 PolarHBondContact O-N 3.47Å; L106-V109 PolarHBondContact O-N 2.95Å; V109-P114 VanDerWaalsContact O-CD 3.23Å; V109-P114 WeakPolarHBondContact O-CD 3.2Å; V109-P114 WeakPolarHBondContact O-CG 3.37Å; V109-L197 HydrophobicContact CB-CD1 4.42Å; V109-L197 HydrophobicContact CG1-CD1 4.36Å; V109-L197 HydrophobicContact CG1-CD2 3.96Å; V109-L197 HydrophobicContact CG2-CD1 4.36Å; V109-M412 HydrophobicContact CG1-CE 4.4Å; V109-L415 HydrophobicContact CG2-CD1 4.2Å; V109-L415 HydrophobicContact CG2-CD2 3.59Å
110	F	96	Very high	93.7	Very high	18 Å²	18	32.7 Å²	32.7	8%	0.079	16%	0.158	C	C	.	.	I	π-helix	trans	-99.2	-13.1	-172.1	-69.7	-72.8	0	0	0	114.9	L106 F144 I147 C148 L151 L197	L106-F110 HydrophobicContact CD2-CD2 3.96Å; L106-F110 HydrophobicContact CD2-CE2 3.68Å; L106-F110 WeakPolarHBondContact O-CB 3.19Å; L106-F110 WeakPolarHBondContact O-CD2 3.37Å; L106-F110 PolarHBondContact O-N 3.42Å; F110-F144 WeakPolarHBondContact CD1-O 3.3Å; F110-F144 WeakPolarHBondContact O-CB 3.39Å; F110-I147 HydrophobicContact CE1-CB 4.5Å; F110-I147 HydrophobicContact CE1-CG2 3.88Å; F110-C148 HydrophobicContact CB-CB 3.65Å; F110-C148 HydrophobicContact CD1-CB 3.97Å; F110-C148 HydrophobicContact CD2-CB 3.83Å; F110-C148 HydrophobicContact CE2-CB 4.46Å; F110-C148 HydrophobicContact CG-CB 3.56Å; F110-L151 HydrophobicContact CE1-CD1 4.22Å; F110-L151 HydrophobicContact CE2-CD1 4.22Å; F110-L151 HydrophobicContact CZ-CD1 3.53Å; F110-L197 HydrophobicContact CE2-CD1 4.07Å; F110-L197 HydrophobicContact CE2-CD2 3.9Å; F110-L197 HydrophobicContact CE2-CG 4.2Å; F110-L197 HydrophobicContact CZ-CD2 3.78Å; F110-L197 HydrophobicContact CZ-CG 4.46Å
111	F	95.2	Very high	93.3	Very high	63 Å²	63	33 Å²	33	28%	0.276	15%	0.153	S	C	.	.	I	π-helix	trans	-127	-62.3	179.8	-179	-95.7	0	0	0	112.1	F107 F115 L138 T141 V145	F107-F111 HydrophobicContact CD2-CB 4.1Å; F107-F111 HydrophobicContact CD2-CD1 4Å; F107-F111 HydrophobicContact CD2-CG 4.32Å; F107-F111 HydrophobicContact CE1-CD1 4.34Å; F107-F111 HydrophobicContact CE2-CB 4.16Å; F107-F111 AromaticContact CE2-CD1 3.2Å; F107-F111 HydrophobicContact CE2-CD1 3.2Å; F107-F111 AromaticContact CE2-CE1 3.78Å; F107-F111 HydrophobicContact CE2-CE1 3.78Å; F107-F111 AromaticContact CE2-CG 3.89Å; F107-F111 HydrophobicContact CE2-CG 3.89Å; F107-F111 AromaticContact CZ-CD1 3.41Å; F107-F111 HydrophobicContact CZ-CD1 3.41Å; F107-F111 VanDerWaalsContact CZ-CD1 3.41Å; F107-F111 AromaticContact CZ-CE1 3.83Å; F107-F111 HydrophobicContact CZ-CE1 3.83Å; F107-F111 HydrophobicContact CZ-CG 4.46Å; F107-F111 WeakPolarHBondContact O-CA 3.48Å; F107-F111 WeakPolarHBondContact O-CB 3.38Å; F107-F111 PolarHBondContact O-N 3.26Å; F111-F115 WeakPolarHBondContact O-CB 3.46Å; F111-F115 PolarHBondContact O-N 2.83Å; F111-L138 HydrophobicContact CE2-CD2 4.3Å; F111-T141 HydrophobicContact CD2-CG2 3.83Å; F111-T141 HydrophobicContact CE2-CG2 4.31Å; F111-T141 HydrophobicContact CG-CG2 4.43Å; F111-T141 WeakPolarHBondContact O-CG2 3.08Å; F111-V145 HydrophobicContact CB-CG2 4.44Å; F111-V145 HydrophobicContact CD2-CG2 3.76Å
112	W	95.4	Very high	92.7	Very high	78 Å²	78	33.6 Å²	33.6	30%	0.295	16%	0.155	S	C	.	.	I	π-helix	trans	-70.4	-48.4	-166.8	-171.6	-108.9	0	0	0	113.7	T46 F107 F115 V116	T46-W112 HydrophobicContact CG2-CG 4.5Å; T46-W112 VanDerWaalsContact CG2-NE1 3.33Å; T46-W112 PolarHBondContact OG1-NE1 3.21Å; F107-W112 HydrophobicContact CD1-CB 4.21Å; F107-W112 HydrophobicContact CE1-CB 3.82Å; F107-W112 HydrophobicContact CE1-CE3 4.48Å; F107-W112 HydrophobicContact CE1-CG 4.29Å; F107-W112 HydrophobicContact CZ-CB 4.39Å; F107-W112 HydrophobicContact CZ-CE3 4.42Å; F107-W112 PolarHBondContact O-N 3.03Å; W112-F115 HydrophobicContact CE3-CD1 4.47Å; W112-F115 HydrophobicContact CZ3-CD1 4.4Å; W112-F115 PolarHBondContact O-N 3.26Å; W112-V116 HydrophobicContact CD2-CG2 4.3Å; W112-V116 HydrophobicContact CZ2-CG2 4.21Å; W112-V116 VanDerWaalsContact O-CG2 3.26Å; W112-V116 WeakPolarHBondContact O-CG2 3.3Å; W112-V116 PolarHBondContact O-N 3.01Å
113	I	94.6	Very high	91.6	Very high	7 Å²	7	37.9 Å²	37.9	4%	0.036	17%	0.174	C	C	.	.	H	α-helix	trans	-63.8	-49.4	177.9	-66	168.3	0	0	0	111.1	T46 C108 F115 V116 Y117 L408 M412	T46-I113 HydrophobicContact CG2-CG1 4.16Å; C108-I113 VanDerWaalsContact O-CB 3.27Å; C108-I113 WeakPolarHBondContact O-CB 3.37Å; C108-I113 VanDerWaalsContact O-CG1 3.25Å; C108-I113 WeakPolarHBondContact O-CG1 3.41Å; C108-I113 PolarHBondContact O-N 3.03Å; I113-F115 VanDerWaalsContact C-N 3.34Å; I113-F115 PolarHBondContact O-N 3.33Å; I113-V116 PolarHBondContact O-N 3.47Å; I113-Y117 VanDerWaalsContact O-CB 3.3Å; I113-Y117 WeakPolarHBondContact O-CB 3.37Å; I113-Y117 PolarHBondContact O-N 3.44Å; I113-L408 HydrophobicContact CG2-CB 4.34Å; I113-M412 HydrophobicContact CD1-CB 4.34Å
114	P	94.9	Very high	90.1	Very high	9 Å²	9	41.5 Å²	41.5	6%	0.058	19%	0.19	C	C	.	.	H	α-helix	trans	-59.2	-42.3	175.6	-25.1	34.5	0	0	0	113	V109 V116 Y117 F118 T141 F144	V109-P114 VanDerWaalsContact O-CD 3.23Å; V109-P114 WeakPolarHBondContact O-CD 3.2Å; V109-P114 WeakPolarHBondContact O-CG 3.37Å; P114-V116 PolarHBondContact O-N 3.31Å; P114-Y117 WeakPolarHBondContact O-CB 3.45Å; P114-Y117 PolarHBondContact O-N 2.97Å; P114-F118 HydrophobicContact CB-CD2 4.48Å; P114-F118 HydrophobicContact CB-CE2 4.31Å; P114-F118 WeakPolarHBondContact O-CD2 3.38Å; P114-F118 PolarHBondContact O-N 3.33Å; P114-T141 HydrophobicContact CB-CG2 4.38Å; P114-F144 HydrophobicContact CB-CB 4.46Å; P114-F144 HydrophobicContact CB-CD1 4.39Å; P114-F144 HydrophobicContact CB-CD2 3.93Å; P114-F144 HydrophobicContact CB-CE2 4.27Å; P114-F144 HydrophobicContact CB-CG 4Å; P114-F144 HydrophobicContact CG-CB 4.23Å; P114-F144 HydrophobicContact CG-CD1 3.92Å; P114-F144 HydrophobicContact CG-CD2 4.32Å; P114-F144 HydrophobicContact CG-CE1 4.36Å; P114-F144 HydrophobicContact CG-CG 3.9Å
115	F	94.3	Very high	88.5	Confident	35 Å²	35	44.3 Å²	44.3	15%	0.154	20%	0.204	C	C	.	.	H	α-helix	trans	-58.5	-50.8	177	172.5	-102.7	0	0	0	112	F111 W112 I113 Y117 F118 Y119 I134 A137 L138 T141	F111-F115 WeakPolarHBondContact O-CB 3.46Å; F111-F115 PolarHBondContact O-N 2.83Å; W112-F115 HydrophobicContact CE3-CD1 4.47Å; W112-F115 HydrophobicContact CZ3-CD1 4.4Å; W112-F115 PolarHBondContact O-N 3.26Å; I113-F115 VanDerWaalsContact C-N 3.34Å; I113-F115 PolarHBondContact O-N 3.33Å; F115-Y117 VanDerWaalsContact C-N 3.3Å; F115-Y117 PolarHBondContact O-N 2.84Å; F115-F118 PolarHBondContact O-N 2.94Å; F115-Y119 WeakPolarHBondContact O-CB 3.2Å; F115-Y119 PolarHBondContact O-N 3.02Å; F115-I134 HydrophobicContact CE2-CG2 4.44Å; F115-A137 HydrophobicContact CD2-CB 4.15Å; F115-A137 HydrophobicContact CE2-CB 4.1Å; F115-L138 HydrophobicContact CD2-CG 4.34Å; F115-L138 HydrophobicContact CE2-CG 4.15Å; F115-T141 WeakPolarHBondContact CA-OG1 3.26Å; F115-T141 HydrophobicContact CB-CG2 4.11Å; F115-T141 PolarHBondContact N-OG1 3.17Å
116	V	93.7	Very high	86.8	Confident	1 Å²	1	52 Å²	52	1%	0.006	25%	0.245	C	C	.	.	H	α-helix	trans	-65.1	-38.3	179.5	178.3	0	0	0	0	110.4	V42 T46 W112 I113 P114 Y120 L408	V42-V116 HydrophobicContact CG1-CG1 4.33Å; V42-V116 HydrophobicContact CG1-CG2 4.25Å; T46-V116 HydrophobicContact CG2-CB 4.44Å; T46-V116 HydrophobicContact CG2-CG2 4.26Å; W112-V116 HydrophobicContact CD2-CG2 4.3Å; W112-V116 HydrophobicContact CZ2-CG2 4.21Å; W112-V116 VanDerWaalsContact O-CG2 3.26Å; W112-V116 WeakPolarHBondContact O-CG2 3.3Å; W112-V116 PolarHBondContact O-N 3.01Å; I113-V116 PolarHBondContact O-N 3.47Å; P114-V116 PolarHBondContact O-N 3.31Å; V116-Y120 HydrophobicContact CG1-CD2 3.7Å; V116-Y120 HydrophobicContact CG1-CE2 3.57Å; V116-Y120 WeakPolarHBondContact O-CD2 3.42Å; V116-Y120 PolarHBondContact O-N 3.09Å; V116-Y120 VanDerWaalsContact O-N 3.1Å; V116-L408 HydrophobicContact CB-CD1 4.34Å; V116-L408 HydrophobicContact CG1-CD1 3.84Å; V116-L408 HydrophobicContact CG1-CD2 4.46Å
117	Y	91.7	Very high	85.2	Confident	42 Å²	42	59.5 Å²	59.5	17%	0.165	29%	0.285	C	S	.	.	H	α-helix	trans	-58.7	-55.8	175.4	174.7	-94.1	0	0	0	112.2	I113 P114 F115 Y119 Y120 E121 Q405 F409	I113-Y117 VanDerWaalsContact O-CB 3.3Å; I113-Y117 WeakPolarHBondContact O-CB 3.37Å; I113-Y117 PolarHBondContact O-N 3.44Å; P114-Y117 WeakPolarHBondContact O-CB 3.45Å; P114-Y117 PolarHBondContact O-N 2.97Å; F115-Y117 VanDerWaalsContact C-N 3.3Å; F115-Y117 PolarHBondContact O-N 2.84Å; Y117-Y119 VanDerWaalsContact C-N 3.33Å; Y117-Y119 PolarHBondContact O-N 3.45Å; Y117-Y120 PolarHBondContact O-N 2.9Å; Y117-Y120 VanDerWaalsContact O-N 3.14Å; Y117-E121 PolarHBondContact O-N 2.85Å; Y117-Q405 HydrophobicContact CD2-CB 4.03Å; Y117-Q405 HydrophobicContact CD2-CG 4.05Å; Y117-Q405 HydrophobicContact CE2-CB 3.74Å; Y117-Q405 HydrophobicContact CE2-CG 3.85Å; Y117-F409 HydrophobicContact CD2-CD2 4.16Å; Y117-F409 AromaticContact CD2-CE2 3.82Å; Y117-F409 HydrophobicContact CD2-CE2 3.82Å; Y117-F409 HydrophobicContact CE1-CE2 4.48Å; Y117-F409 AromaticContact CE2-CD2 3.86Å; Y117-F409 HydrophobicContact CE2-CD2 3.86Å; Y117-F409 AromaticContact CE2-CE2 3.31Å; Y117-F409 HydrophobicContact CE2-CE2 3.31Å; Y117-F409 HydrophobicContact CE2-CZ 4.33Å; Y117-F409 AromaticContact CZ-CE2 3.7Å
118	F	91.3	Very high	83.8	Confident	46 Å²	46	57 Å²	57	20%	0.202	28%	0.278	C	S	.	.	H	α-helix	trans	-68.1	-32.2	-179.4	-69.6	-62.4	0	0	0	113	P114 F115 Y120 E121 E122 A137 Y140 F144	P114-F118 HydrophobicContact CB-CD2 4.48Å; P114-F118 HydrophobicContact CB-CE2 4.31Å; P114-F118 WeakPolarHBondContact O-CD2 3.38Å; P114-F118 PolarHBondContact O-N 3.33Å; F115-F118 PolarHBondContact O-N 2.94Å; F118-Y120 VanDerWaalsContact C-N 3.25Å; F118-Y120 PolarHBondContact O-N 3.11Å; F118-E121 PolarHBondContact O-N 2.78Å; F118-E122 PolarHBondContact O-N 3.06Å; F118-A137 HydrophobicContact CB-CB 4.08Å; F118-Y140 HydrophobicContact CD1-CD2 4.33Å; F118-Y140 HydrophobicContact CD1-CG 4.3Å; F118-Y140 HydrophobicContact CE1-CG 4.42Å; F118-F144 HydrophobicContact CE2-CD2 4.17Å; F118-F144 AromaticContact CE2-CE2 3.61Å; F118-F144 HydrophobicContact CE2-CE2 3.61Å; F118-F144 HydrophobicContact CE2-CZ 4.49Å; F118-F144 AromaticContact CZ-CE2 3.9Å; F118-F144 HydrophobicContact CZ-CE2 3.9Å
119	Y	89.3	Confident	83	Confident	56 Å²	56	60.2 Å²	60.2	22%	0.22	30%	0.3	C	S	.	.	H	α-helix	trans	-59.7	-39.6	172.7	178.1	-97.9	0	0	0	111.2	F115 Y117 K123 Q133 I134	F115-Y119 WeakPolarHBondContact O-CB 3.2Å; F115-Y119 PolarHBondContact O-N 3.02Å; Y117-Y119 VanDerWaalsContact C-N 3.33Å; Y117-Y119 PolarHBondContact O-N 3.45Å; Y119-K123 PolarHBondContact O-N 2.96Å; Y119-Q133 HydrophobicContact CD2-CG 3.92Å; Y119-Q133 HydrophobicContact CE2-CG 3.95Å; Y119-Q133 PolarHBondContact O-NE2 3.34Å; Y119-I134 HydrophobicContact CD2-CG1 4.2Å; Y119-I134 HydrophobicContact CE2-CG1 3.88Å
120	Y	83.3	Confident	82.3	Confident	13 Å²	13	67.7 Å²	67.7	5%	0.051	33%	0.332	C	S	.	.	H	α-helix	trans	-77.7	-35.4	177.5	-82	-65.5	0	0	0	114.1	E40 V42 S43 V116 Y117 F118 E122 K123	E40-Y120 HydrophobicContact CB-CE1 3.59Å; E40-Y120 VanDerWaalsContact CB-OH 3.3Å; E40-Y120 WeakPolarHBondContact CB-OH 3.5Å; E40-Y120 HydrophobicContact CG-CD1 4.38Å; E40-Y120 HydrophobicContact CG-CE1 3.54Å; V42-Y120 HydrophobicContact CB-CE2 4.29Å; V42-Y120 VanDerWaalsContact CB-OH 3.31Å; V42-Y120 WeakPolarHBondContact CB-OH 3.43Å; S43-Y120 PolarHBondContact N-OH 3.04Å; V116-Y120 HydrophobicContact CG1-CD2 3.7Å; V116-Y120 HydrophobicContact CG1-CE2 3.57Å; V116-Y120 WeakPolarHBondContact O-CD2 3.42Å; V116-Y120 PolarHBondContact O-N 3.09Å; V116-Y120 VanDerWaalsContact O-N 3.1Å; Y117-Y120 PolarHBondContact O-N 2.9Å; Y117-Y120 VanDerWaalsContact O-N 3.14Å; F118-Y120 VanDerWaalsContact C-N 3.25Å; F118-Y120 PolarHBondContact O-N 3.11Å; Y120-E122 VanDerWaalsContact C-N 3.29Å; Y120-E122 PolarHBondContact O-N 3.3Å; Y120-K123 HydrophobicContact CD1-CD 4.33Å; Y120-K123 HydrophobicContact CE1-CD 4.43Å; Y120-K123 WeakPolarHBondContact O-CB 3.39Å; Y120-K123 PolarHBondContact O-N 3.08Å; Y120-K123 VanDerWaalsContact O-N 3.16Å
121	E	84.2	Confident	81.6	Confident	89 Å²	89	71.6 Å²	71.6	42%	0.416	36%	0.361	S	S	.	.	H	α-helix	trans	-58.3	-43.3	174.2	-168.1	75.4	-157.9	0	0	111.6	Y117 F118 K123 D124 Q405	Y117-E121 PolarHBondContact O-N 2.85Å; F118-E121 PolarHBondContact O-N 2.78Å; E121-K123 PolarHBondContact O-N 3.47Å; E121-D124 PolarHBondContact O-N 2.99Å; E121-Q405 PolarHBondContact OE2-NE2 3.36Å; E121-Q405 PolarHBondContact OE2-OE1 3.23Å
122	E	80.8	Confident	81	Confident	44 Å²	44	71.9 Å²	71.9	21%	0.206	37%	0.368	C	S	.	.	G	3₁₀ helix	trans	-75	-11.9	179.9	-164.8	78	-179.2	0	0	113	F118 Y120 D124 Q133 T136	F118-E122 PolarHBondContact O-N 3.06Å; Y120-E122 VanDerWaalsContact C-N 3.29Å; Y120-E122 PolarHBondContact O-N 3.3Å; E122-D124 VanDerWaalsContact C-N 3.25Å; E122-D124 PolarHBondContact O-N 3.04Å; E122-Q133 HydrophobicContact CB-CG 3.94Å; E122-Q133 HydrophobicContact CG-CB 4.44Å; E122-Q133 HydrophobicContact CG-CG 3.96Å; E122-T136 HydrophobicContact CG-CG2 4.45Å
123	K	71.2	Confident	80.4	Confident	91 Å²	91	68.7 Å²	68.7	40%	0.396	36%	0.356	S	S	.	.	G	3₁₀ helix	trans	-69.9	-26.9	177.6	-171.1	174.4	170.7	174.5	0	111.8	E40 Y119 Y120 E121 D125 Q133	E40-K123 IonicContact OE1-NZ 2.8Å; E40-K123 PolarHBondContact OE1-NZ 2.83Å; E40-K123 IonicContact OE2-NZ 3.91Å; Y119-K123 PolarHBondContact O-N 2.96Å; Y120-K123 HydrophobicContact CD1-CD 4.33Å; Y120-K123 HydrophobicContact CE1-CD 4.43Å; Y120-K123 WeakPolarHBondContact O-CB 3.39Å; Y120-K123 PolarHBondContact O-N 3.08Å; Y120-K123 VanDerWaalsContact O-N 3.16Å; E121-K123 PolarHBondContact O-N 3.47Å; K123-D125 PolarHBondContact O-N 3.31Å; K123-Q133 VanDerWaalsContact CB-NE2 3.34Å
124	D	62	Low	80.1	Confident	120 Å²	120	71.8 Å²	71.8	64%	0.642	37%	0.372	S	S	*	.	G	3₁₀ helix	trans	-76	-5	-174.9	-68.1	-14.7	0	0	0	112.7	E121 E122	E121-D124 PolarHBondContact O-N 2.99Å; E122-D124 VanDerWaalsContact C-N 3.25Å; E122-D124 PolarHBondContact O-N 3.04Å
125	D	63	Low	79.8	Confident	102 Å²	102	79 Å²	79	55%	0.545	40%	0.403	S	S	.	.	S	Bend	trans	-93.5	97.4	168.9	-72.3	-28.2	0	0	0	110.4	K123 D127 T128	K123-D125 PolarHBondContact O-N 3.31Å; D125-D127 PolarHBondContact O-N 3.44Å; D125-T128 PolarHBondContact O-N 3.49Å
126	D	60	Low	79.5	Confident	163 Å²	163	78.8 Å²	78.8	87%	0.872	40%	0.404	S	S	*	.	T	Hydrogen-bonded Turn	trans	-55.3	-13.5	-167.7	-88.2	-32.1	0	0	0	117.1
127	D	60.8	Low	79.4	Confident	167 Å²	167	78.7 Å²	78.7	89%	0.893	40%	0.404	S	S	*	.	T	Hydrogen-bonded Turn	trans	-106.5	5.4	-173.1	-77	-35.3	0	0	0	115.1	D125	D125-D127 PolarHBondContact O-N 3.44Å
128	T	66.4	Low	79.3	Confident	48 Å²	48	80.5 Å²	80.5	29%	0.294	42%	0.416	S	S	.	.			trans	-90.5	126.3	-172.2	-58.7	0	0	0	0	113.7	D125 T132 Q133	D125-T128 PolarHBondContact O-N 3.49Å; T128-T132 HydrophobicContact CG2-CG2 4.04Å; T128-Q133 HydrophobicContact CG2-CB 4.34Å
129	S	79.4	Confident	79.4	Confident	68 Å²	68	85.5 Å²	85.5	48%	0.476	44%	0.437	S	S	.	.			trans	-61.7	139.2	173.3	92.4	0	0	0	0	111.5	C131 T132 Q133	S129-C131 PolarHBondContact O-N 3.23Å; S129-T132 WeakPolarHBondContact O-CA 3.5Å; S129-T132 WeakPolarHBondContact O-CB 3.48Å; S129-T132 PolarHBondContact O-N 2.95Å; S129-T132 PolarHBondContact OG-N 3.26Å; S129-T132 PolarHBondContact OG-OG1 3.43Å; S129-Q133 PolarHBondContact O-N 2.76Å
130	K	80.3	Confident	79.4	Confident	161 Å²	161	88.5 Å²	88.5	70%	0.7	45%	0.449	S	S	*	.	H	α-helix	trans	-51.6	-34	-179.4	-66.7	-176	179.8	178.7	0	113.8	I134	K130-I134 WeakPolarHBondContact O-CG1 3.28Å; K130-I134 PolarHBondContact O-N 3.48Å; K130-I134 VanDerWaalsContact O-N 3.12Å
131	C	81	Confident	79.9	Confident	100 Å²	100	87.9 Å²	87.9	68%	0.676	45%	0.447	S	S	*	.	H	α-helix	trans	-70	-40.9	178.6	-171.8	0	0	0	0	111.6	S129 K135	S129-C131 PolarHBondContact O-N 3.23Å; C131-K135 WeakPolarHBondContact O-CB 3.35Å; C131-K135 PolarHBondContact O-N 3.15Å; C131-K135 VanDerWaalsContact O-N 3.11Å
132	T	82.6	Confident	80.4	Confident	69 Å²	69	88.8 Å²	88.8	42%	0.423	45%	0.454	S	S	.	.	H	α-helix	trans	-63.6	-43.8	174.2	-48	0	0	0	0	110.6	T128 S129 I134 K135 T136	T128-T132 HydrophobicContact CG2-CG2 4.04Å; S129-T132 WeakPolarHBondContact O-CA 3.5Å; S129-T132 WeakPolarHBondContact O-CB 3.48Å; S129-T132 PolarHBondContact O-N 2.95Å; S129-T132 PolarHBondContact OG-N 3.26Å; S129-T132 PolarHBondContact OG-OG1 3.43Å; T132-I134 PolarHBondContact O-N 2.9Å; T132-K135 WeakPolarHBondContact O-CB 3.42Å; T132-K135 PolarHBondContact O-N 3.43Å; T132-K135 VanDerWaalsContact O-N 3.16Å; T132-T136 PolarHBondContact O-N 2.9Å; T132-T136 PolarHBondContact O-OG1 2.97Å; T132-T136 VanDerWaalsContact O-OG1 3.08Å
133	Q	84.4	Confident	81	Confident	12 Å²	12	88.6 Å²	88.6	6%	0.056	46%	0.464	C	S	.	.	H	α-helix	trans	-57.4	-48.5	177.9	-170	-176.6	11.6	0	0	112.5	Y119 E122 K123 T128 S129 K135 T136 A137	Y119-Q133 HydrophobicContact CD2-CG 3.92Å; Y119-Q133 HydrophobicContact CE2-CG 3.95Å; Y119-Q133 PolarHBondContact O-NE2 3.34Å; E122-Q133 HydrophobicContact CB-CG 3.94Å; E122-Q133 HydrophobicContact CG-CB 4.44Å; E122-Q133 HydrophobicContact CG-CG 3.96Å; K123-Q133 VanDerWaalsContact CB-NE2 3.34Å; T128-Q133 HydrophobicContact CG2-CB 4.34Å; S129-Q133 PolarHBondContact O-N 2.76Å; Q133-K135 VanDerWaalsContact C-N 3.32Å; Q133-K135 PolarHBondContact O-N 3.05Å; Q133-T136 PolarHBondContact O-N 3.41Å; Q133-A137 WeakPolarHBondContact O-CB 2.98Å; Q133-A137 PolarHBondContact O-N 3.09Å
134	I	88.3	Confident	82.1	Confident	72 Å²	72	87.9 Å²	87.9	37%	0.369	46%	0.461	S	S	.	.	H	α-helix	trans	-62.3	-41.6	177.3	-68.3	167.3	0	0	0	110.9	F115 Y119 K130 T132 A137 L138	F115-I134 HydrophobicContact CE2-CG2 4.44Å; Y119-I134 HydrophobicContact CD2-CG1 4.2Å; Y119-I134 HydrophobicContact CE2-CG1 3.88Å; K130-I134 WeakPolarHBondContact O-CG1 3.28Å; K130-I134 PolarHBondContact O-N 3.48Å; K130-I134 VanDerWaalsContact O-N 3.12Å; T132-I134 PolarHBondContact O-N 2.9Å; I134-A137 PolarHBondContact O-N 2.92Å; I134-L138 HydrophobicContact CG2-CD1 3.98Å; I134-L138 WeakPolarHBondContact O-CB 3.31Å; I134-L138 PolarHBondContact O-N 3.44Å
135	K	88.8	Confident	83.7	Confident	161 Å²	161	84.8 Å²	84.8	70%	0.7	45%	0.446	S	S	*	.	H	α-helix	trans	-64.7	-42.2	179.3	-172.7	179.2	179.8	-178.7	0	111.6	C131 T132 Q133 K139	C131-K135 WeakPolarHBondContact O-CB 3.35Å; C131-K135 PolarHBondContact O-N 3.15Å; C131-K135 VanDerWaalsContact O-N 3.11Å; T132-K135 WeakPolarHBondContact O-CB 3.42Å; T132-K135 PolarHBondContact O-N 3.43Å; T132-K135 VanDerWaalsContact O-N 3.16Å; Q133-K135 VanDerWaalsContact C-N 3.32Å; Q133-K135 PolarHBondContact O-N 3.05Å; K135-K139 WeakPolarHBondContact O-CB 3.5Å; K135-K139 PolarHBondContact O-N 3.46Å
136	T	87.9	Confident	85.3	Confident	29 Å²	29	83.5 Å²	83.5	18%	0.178	44%	0.442	C	S	.	.	H	α-helix	trans	-65.6	-46.4	176.4	-59.3	0	0	0	0	110.9	E122 T132 Q133 L138 K139 Y140	E122-T136 HydrophobicContact CG-CG2 4.45Å; T132-T136 PolarHBondContact O-N 2.9Å; T132-T136 PolarHBondContact O-OG1 2.97Å; T132-T136 VanDerWaalsContact O-OG1 3.08Å; Q133-T136 PolarHBondContact O-N 3.41Å; T136-L138 PolarHBondContact O-N 2.73Å; T136-K139 WeakPolarHBondContact O-CB 3.42Å; T136-K139 PolarHBondContact O-N 3.25Å; T136-K139 VanDerWaalsContact O-N 3.15Å; T136-Y140 HydrophobicContact CG2-CD2 3.84Å; T136-Y140 HydrophobicContact CG2-CE2 3.39Å; T136-Y140 VanDerWaalsContact O-CD2 3.23Å; T136-Y140 WeakPolarHBondContact O-CD2 3.31Å; T136-Y140 PolarHBondContact O-N 3.36Å; T136-Y140 VanDerWaalsContact O-N 3.13Å
137	A	90.3	Very high	86.9	Confident	0 Å²	0	79.9 Å²	79.9	0%	0	42%	0.421	C	S	.	.	H	α-helix	trans	-59.9	-43	176.3	0	0	0	0	0	112.6	F115 F118 Q133 I134 Y140 T141	F115-A137 HydrophobicContact CD2-CB 4.15Å; F115-A137 HydrophobicContact CE2-CB 4.1Å; F118-A137 HydrophobicContact CB-CB 4.08Å; Q133-A137 WeakPolarHBondContact O-CB 2.98Å; Q133-A137 PolarHBondContact O-N 3.09Å; I134-A137 PolarHBondContact O-N 2.92Å; A137-Y140 PolarHBondContact O-N 2.99Å; A137-T141 WeakPolarHBondContact O-CB 3.25Å; A137-T141 PolarHBondContact O-N 3.39Å; A137-T141 PolarHBondContact O-OG1 3.44Å
138	L	90.7	Very high	88.6	Confident	79 Å²	79	72.8 Å²	72.8	41%	0.414	39%	0.385	S	S	.	.	H	α-helix	trans	-62.7	-40.9	174.7	-96.4	159.1	0	0	0	112.3	F111 F115 I134 T136 Y140 T141 L142	F111-L138 HydrophobicContact CE2-CD2 4.3Å; F115-L138 HydrophobicContact CD2-CG 4.34Å; F115-L138 HydrophobicContact CE2-CG 4.15Å; I134-L138 HydrophobicContact CG2-CD1 3.98Å; I134-L138 WeakPolarHBondContact O-CB 3.31Å; I134-L138 PolarHBondContact O-N 3.44Å; T136-L138 PolarHBondContact O-N 2.73Å; L138-Y140 VanDerWaalsContact C-N 3.34Å; L138-Y140 PolarHBondContact O-N 2.99Å; L138-T141 PolarHBondContact O-N 3.41Å; L138-L142 PolarHBondContact O-N 2.83Å
139	K	92.2	Very high	89.8	Confident	151 Å²	151	72.7 Å²	72.7	66%	0.657	39%	0.389	S	S	*	.	H	α-helix	trans	-59.3	-44.6	177.8	-178.3	-172.7	173.5	-169.7	0	111.4	K135 T136 L142	K135-K139 WeakPolarHBondContact O-CB 3.5Å; K135-K139 PolarHBondContact O-N 3.46Å; T136-K139 WeakPolarHBondContact O-CB 3.42Å; T136-K139 PolarHBondContact O-N 3.25Å; T136-K139 VanDerWaalsContact O-N 3.15Å; K139-L142 WeakPolarHBondContact O-CB 3.33Å
140	Y	89.9	Confident	90.6	Very high	119 Å²	119	73.9 Å²	73.9	47%	0.467	39%	0.389	S	S	.	.	H	α-helix	trans	-74.3	-34.5	177.8	-66.9	-59.6	0	0	0	112.8	F118 T136 A137 L138 L142 G143	F118-Y140 HydrophobicContact CD1-CD2 4.33Å; F118-Y140 HydrophobicContact CD1-CG 4.3Å; F118-Y140 HydrophobicContact CE1-CG 4.42Å; T136-Y140 HydrophobicContact CG2-CD2 3.84Å; T136-Y140 HydrophobicContact CG2-CE2 3.39Å; T136-Y140 VanDerWaalsContact O-CD2 3.23Å; T136-Y140 WeakPolarHBondContact O-CD2 3.31Å; T136-Y140 PolarHBondContact O-N 3.36Å; T136-Y140 VanDerWaalsContact O-N 3.13Å; A137-Y140 PolarHBondContact O-N 2.99Å; L138-Y140 VanDerWaalsContact C-N 3.34Å; L138-Y140 PolarHBondContact O-N 2.99Å; Y140-L142 VanDerWaalsContact C-N 3.26Å; Y140-L142 PolarHBondContact O-N 2.9Å; Y140-G143 PolarHBondContact O-N 3.37Å
141	T	94.2	Very high	91.2	Very high	1 Å²	1	67.7 Å²	67.7	1%	0.006	36%	0.364	C	S	.	.	H	α-helix	trans	-64.4	-31.3	174.6	-56	0	0	0	0	112.3	F111 P114 F115 A137 L138 G143 F144 V145	F111-T141 HydrophobicContact CD2-CG2 3.83Å; F111-T141 HydrophobicContact CE2-CG2 4.31Å; F111-T141 HydrophobicContact CG-CG2 4.43Å; F111-T141 WeakPolarHBondContact O-CG2 3.08Å; P114-T141 HydrophobicContact CB-CG2 4.38Å; F115-T141 WeakPolarHBondContact CA-OG1 3.26Å; F115-T141 HydrophobicContact CB-CG2 4.11Å; F115-T141 PolarHBondContact N-OG1 3.17Å; A137-T141 WeakPolarHBondContact O-CB 3.25Å; A137-T141 PolarHBondContact O-N 3.39Å; A137-T141 PolarHBondContact O-OG1 3.44Å; L138-T141 PolarHBondContact O-N 3.41Å; T141-G143 PolarHBondContact O-N 3.16Å; T141-G143 VanDerWaalsContact O-N 3.13Å; T141-F144 WeakPolarHBondContact O-CB 3.35Å; T141-F144 PolarHBondContact O-N 3.01Å; T141-V145 HydrophobicContact CG2-CG2 4.34Å; T141-V145 PolarHBondContact O-N 3.48Å; T141-V145 VanDerWaalsContact O-N 3.15Å
142	L	93.9	Very high	91.7	Very high	108 Å²	108	65.8 Å²	65.8	57%	0.565	35%	0.347	S	S	*	.	H	α-helix	trans	-54.7	-35	179.6	-172	67.6	0	0	0	112.4	L138 K139 Y140 F144 V145 V146	L138-L142 PolarHBondContact O-N 2.83Å; K139-L142 WeakPolarHBondContact O-CB 3.33Å; Y140-L142 VanDerWaalsContact C-N 3.26Å; Y140-L142 PolarHBondContact O-N 2.9Å; L142-F144 VanDerWaalsContact C-N 3.34Å; L142-F144 PolarHBondContact O-N 3.29Å; L142-V145 PolarHBondContact O-N 3.47Å; L142-V146 WeakPolarHBondContact O-CG2 3.31Å; L142-V146 PolarHBondContact O-N 2.66Å
143	G	93.8	Very high	92	Very high	40 Å²	40	67 Å²	67	41%	0.412	35%	0.35	S	S	.	.	H	α-helix	trans	-59.6	-42.3	175.6	0	0	0	0	0	113	Y140 T141 V146 I147	Y140-G143 PolarHBondContact O-N 3.37Å; T141-G143 PolarHBondContact O-N 3.16Å; T141-G143 VanDerWaalsContact O-N 3.13Å; G143-V146 PolarHBondContact O-N 2.9Å; G143-I147 WeakPolarHBondContact O-CG1 3.14Å; G143-I147 PolarHBondContact O-N 3.13Å; G143-I147 VanDerWaalsContact O-N 3.09Å
144	F	94.5	Very high	92.2	Very high	75 Å²	75	70.2 Å²	70.2	33%	0.329	37%	0.367	S	S	.	.	H	α-helix	trans	-69.4	-36.7	177.1	-69.2	-96.8	0	0	0	112.1	F110 P114 F118 T141 L142 V146 I147 C148	F110-F144 WeakPolarHBondContact CD1-O 3.3Å; F110-F144 WeakPolarHBondContact O-CB 3.39Å; P114-F144 HydrophobicContact CB-CB 4.46Å; P114-F144 HydrophobicContact CB-CD1 4.39Å; P114-F144 HydrophobicContact CB-CD2 3.93Å; P114-F144 HydrophobicContact CB-CE2 4.27Å; P114-F144 HydrophobicContact CB-CG 4Å; P114-F144 HydrophobicContact CG-CB 4.23Å; P114-F144 HydrophobicContact CG-CD1 3.92Å; P114-F144 HydrophobicContact CG-CD2 4.32Å; P114-F144 HydrophobicContact CG-CE1 4.36Å; P114-F144 HydrophobicContact CG-CG 3.9Å; F118-F144 HydrophobicContact CE2-CD2 4.17Å; F118-F144 AromaticContact CE2-CE2 3.61Å; F118-F144 HydrophobicContact CE2-CE2 3.61Å; F118-F144 HydrophobicContact CE2-CZ 4.49Å; F118-F144 AromaticContact CZ-CE2 3.9Å; F118-F144 HydrophobicContact CZ-CE2 3.9Å; T141-F144 WeakPolarHBondContact O-CB 3.35Å; T141-F144 PolarHBondContact O-N 3.01Å; L142-F144 VanDerWaalsContact C-N 3.34Å; L142-F144 PolarHBondContact O-N 3.29Å; F144-V146 VanDerWaalsContact C-N 3.35Å; F144-I147 PolarHBondContact O-N 3.31Å; F144-C148 PolarHBondContact O-N 3.25Å
145	V	95.5	Very high	92.1	Very high	55 Å²	55	66.9 Å²	66.9	33%	0.333	35%	0.35	S	S	.	.	H	α-helix	trans	-64	-41.1	174.3	178.3	0	0	0	0	111.1	F111 T141 L142 C148 A149	F111-V145 HydrophobicContact CB-CG2 4.44Å; F111-V145 HydrophobicContact CD2-CG2 3.76Å; T141-V145 HydrophobicContact CG2-CG2 4.34Å; T141-V145 PolarHBondContact O-N 3.48Å; T141-V145 VanDerWaalsContact O-N 3.15Å; L142-V145 PolarHBondContact O-N 3.47Å; V145-C148 WeakPolarHBondContact O-CB 3.3Å; V145-C148 PolarHBondContact O-N 3.03Å; V145-A149 PolarHBondContact O-N 3.17Å
146	V	95.8	Very high	91.9	Very high	76 Å²	76	60.3 Å²	60.3	46%	0.461	33%	0.326	S	S	.	.	H	α-helix	trans	-62.1	-43.2	174.9	170.9	0	0	0	0	110.8	L142 G143 F144 C148 A149 L150	L142-V146 WeakPolarHBondContact O-CG2 3.31Å; L142-V146 PolarHBondContact O-N 2.66Å; G143-V146 PolarHBondContact O-N 2.9Å; F144-V146 VanDerWaalsContact C-N 3.35Å; V146-C148 VanDerWaalsContact C-N 3.33Å; V146-C148 PolarHBondContact O-N 3.17Å; V146-A149 PolarHBondContact O-N 2.99Å; V146-L150 HydrophobicContact CG1-CD1 4.17Å; V146-L150 HydrophobicContact CG1-CG 4.47Å; V146-L150 WeakPolarHBondContact O-CG 3.07Å; V146-L150 PolarHBondContact O-N 3.42Å
147	I	95.4	Very high	91.7	Very high	86 Å²	86	66.5 Å²	66.5	44%	0.441	35%	0.351	S	S	.	.	H	α-helix	trans	-59.9	-44.4	174.7	-66.5	166.1	0	0	0	110.8	F110 G143 F144 A149 L150 L151	F110-I147 HydrophobicContact CE1-CB 4.5Å; F110-I147 HydrophobicContact CE1-CG2 3.88Å; G143-I147 WeakPolarHBondContact O-CG1 3.14Å; G143-I147 PolarHBondContact O-N 3.13Å; G143-I147 VanDerWaalsContact O-N 3.09Å; F144-I147 PolarHBondContact O-N 3.31Å; I147-A149 PolarHBondContact O-N 3.49Å; I147-L150 PolarHBondContact O-N 2.98Å; I147-L151 HydrophobicContact CG2-CD1 4.28Å; I147-L151 WeakPolarHBondContact O-CG 3.41Å; I147-L151 PolarHBondContact O-N 3.14Å
148	C	94.9	Very high	91.2	Very high	18 Å²	18	68.3 Å²	68.3	12%	0.122	36%	0.361	C	S	.	.	H	α-helix	trans	-60.3	-45.3	176.2	-170.8	0	0	0	0	112.1	F110 F144 V145 V146 L150 L151 L152	F110-C148 HydrophobicContact CB-CB 3.65Å; F110-C148 HydrophobicContact CD1-CB 3.97Å; F110-C148 HydrophobicContact CD2-CB 3.83Å; F110-C148 HydrophobicContact CE2-CB 4.46Å; F110-C148 HydrophobicContact CG-CB 3.56Å; F144-C148 PolarHBondContact O-N 3.25Å; V145-C148 WeakPolarHBondContact O-CB 3.3Å; V145-C148 PolarHBondContact O-N 3.03Å; V146-C148 VanDerWaalsContact C-N 3.33Å; V146-C148 PolarHBondContact O-N 3.17Å; C148-L150 VanDerWaalsContact C-N 3.33Å; C148-L150 PolarHBondContact O-N 3.34Å; C148-L151 PolarHBondContact O-N 2.92Å; C148-L152 WeakPolarHBondContact O-CG 3.3Å; C148-L152 PolarHBondContact O-N 3.37Å
149	A	93.3	Very high	90	Very high	46 Å²	46	68.7 Å²	68.7	38%	0.38	37%	0.369	S	S	.	.	H	α-helix	trans	-61.2	-41.6	176.7	0	0	0	0	0	111.6	V145 V146 I147 L152 L153	V145-A149 PolarHBondContact O-N 3.17Å; V146-A149 PolarHBondContact O-N 2.99Å; I147-A149 PolarHBondContact O-N 3.49Å; A149-L152 PolarHBondContact O-N 3.33Å; A149-L153 WeakPolarHBondContact O-CB 3.4Å; A149-L153 VanDerWaalsContact O-CG 3.23Å; A149-L153 WeakPolarHBondContact O-CG 3.46Å; A149-L153 PolarHBondContact O-N 3.3Å
150	L	94.5	Very high	88.7	Confident	93 Å²	93	63.8 Å²	63.8	49%	0.487	35%	0.349	S	S	.	.	H	α-helix	trans	-62.9	-45.1	174.8	-71	171.6	0	0	0	111.9	V146 I147 C148 L152 L153 I154	V146-L150 HydrophobicContact CG1-CD1 4.17Å; V146-L150 HydrophobicContact CG1-CG 4.47Å; V146-L150 WeakPolarHBondContact O-CG 3.07Å; V146-L150 PolarHBondContact O-N 3.42Å; I147-L150 PolarHBondContact O-N 2.98Å; C148-L150 VanDerWaalsContact C-N 3.33Å; C148-L150 PolarHBondContact O-N 3.34Å; L150-L152 PolarHBondContact O-N 3.22Å; L150-L153 PolarHBondContact O-N 2.93Å; L150-I154 WeakPolarHBondContact O-CB 3.35Å; L150-I154 WeakPolarHBondContact O-CD1 3.29Å; L150-I154 WeakPolarHBondContact O-CG1 3.12Å; L150-I154 PolarHBondContact O-N 2.78Å
151	L	93.4	Very high	87	Confident	32 Å²	32	64.3 Å²	64.3	17%	0.168	36%	0.36	C	S	.	.	H	α-helix	trans	-61.3	-43.5	176.7	-70.8	174.5	0	0	0	111.9	F110 I147 C148 I154 G155 F192	F110-L151 HydrophobicContact CE1-CD1 4.22Å; F110-L151 HydrophobicContact CE2-CD1 4.22Å; F110-L151 HydrophobicContact CZ-CD1 3.53Å; I147-L151 HydrophobicContact CG2-CD1 4.28Å; I147-L151 WeakPolarHBondContact O-CG 3.41Å; I147-L151 PolarHBondContact O-N 3.14Å; C148-L151 PolarHBondContact O-N 2.92Å; L151-I154 PolarHBondContact O-N 3.34Å; L151-G155 PolarHBondContact O-N 3.08Å; L151-F192 HydrophobicContact CD2-CE1 3.95Å; L151-F192 VanDerWaalsContact O-CD1 3.25Å; L151-F192 WeakPolarHBondContact O-CD1 3.05Å
152	L	90.7	Very high	85.1	Confident	60 Å²	60	66 Å²	66	31%	0.314	37%	0.369	S	S	.	.	H	α-helix	trans	-65.9	-41.5	176.9	-71.2	170.7	0	0	0	112.1	L106 C148 A149 L150 G155 A156 A189 S193	L106-L152 HydrophobicContact CD1-CD2 4.34Å; C148-L152 WeakPolarHBondContact O-CG 3.3Å; C148-L152 PolarHBondContact O-N 3.37Å; A149-L152 PolarHBondContact O-N 3.33Å; L150-L152 PolarHBondContact O-N 3.22Å; L152-G155 PolarHBondContact O-N 3.38Å; L152-A156 WeakPolarHBondContact O-CB 3.31Å; L152-A156 PolarHBondContact O-N 3.24Å; L152-A189 HydrophobicContact CB-CB 4.43Å; L152-A189 HydrophobicContact CD2-CB 4.01Å; L152-A189 VanDerWaalsContact O-CB 3.31Å; L152-A189 WeakPolarHBondContact O-CB 3.44Å; L152-S193 WeakPolarHBondContact CD2-OG 3.36Å; L152-S193 PolarHBondContact N-OG 3.1Å
153	L	89.3	Confident	83	Confident	95 Å²	95	63.3 Å²	63.3	50%	0.497	36%	0.358	S	S	.	.	H	α-helix	trans	-63.2	-48.1	175.7	-76.3	170.6	0	0	0	111	A149 L150 G155 A156 F157	A149-L153 WeakPolarHBondContact O-CB 3.4Å; A149-L153 VanDerWaalsContact O-CG 3.23Å; A149-L153 WeakPolarHBondContact O-CG 3.46Å; A149-L153 PolarHBondContact O-N 3.3Å; L150-L153 PolarHBondContact O-N 2.93Å; L153-G155 VanDerWaalsContact C-N 3.33Å; L153-G155 PolarHBondContact O-N 3.02Å; L153-A156 PolarHBondContact O-N 3.44Å; L153-F157 HydrophobicContact CD2-CE2 4.07Å; L153-F157 WeakPolarHBondContact O-CD2 3.42Å; L153-F157 PolarHBondContact O-N 3.19Å
154	I	89.6	Confident	80.7	Confident	79 Å²	79	67.5 Å²	67.5	41%	0.405	38%	0.381	S	S	.	.	H	α-helix	trans	-56.6	-51.6	175.4	-67.9	164.8	0	0	0	108.8	L150 L151 A156 F157 V158 F192	L150-I154 WeakPolarHBondContact O-CB 3.35Å; L150-I154 WeakPolarHBondContact O-CD1 3.29Å; L150-I154 WeakPolarHBondContact O-CG1 3.12Å; L150-I154 PolarHBondContact O-N 2.78Å; L151-I154 PolarHBondContact O-N 3.34Å; I154-A156 VanDerWaalsContact C-N 3.29Å; I154-A156 PolarHBondContact O-N 2.84Å; I154-F157 CarbonylContact O-C 3.23Å; I154-F157 PolarHBondContact O-N 3.36Å; I154-F157 VanDerWaalsContact O-N 3.1Å; I154-V158 HydrophobicContact CG2-CG2 3.44Å; I154-V158 VanDerWaalsContact CG2-CG2 3.44Å; I154-V158 WeakPolarHBondContact O-CB 3.4Å; I154-V158 WeakPolarHBondContact O-CG2 3.27Å; I154-V158 PolarHBondContact O-N 3.23Å; I154-F192 HydrophobicContact CB-CE1 3.98Å; I154-F192 HydrophobicContact CB-CZ 4.26Å; I154-F192 HydrophobicContact CG2-CD1 4.32Å; I154-F192 HydrophobicContact CG2-CE1 3.59Å; I154-F192 HydrophobicContact CG2-CE2 3.91Å; I154-F192 HydrophobicContact CG2-CZ 3.36Å
155	G	86.3	Confident	78.6	Confident	1 Å²	1	70.5 Å²	70.5	1%	0.01	40%	0.401	C	S	.	.	H	α-helix	trans	-60.2	-32.7	179	0	0	0	0	0	115.3	L151 L152 L153 F157 A188 F192	L151-G155 PolarHBondContact O-N 3.08Å; L152-G155 PolarHBondContact O-N 3.38Å; L153-G155 VanDerWaalsContact C-N 3.33Å; L153-G155 PolarHBondContact O-N 3.02Å; G155-F157 VanDerWaalsContact C-N 3.33Å; G155-A188 CarbonylContact O-C 3.49Å; G155-A188 WeakPolarHBondContact O-CB 3.5Å; G155-F192 VanDerWaalsContact CA-CG 3.46Å
156	A	84.6	Confident	76.3	Confident	24 Å²	24	73.9 Å²	73.9	20%	0.198	41%	0.411	C	S	.	.	H	α-helix	trans	-70.3	-30.2	177.3	0	0	0	0	0	112.9	L152 L153 I154 A189	L152-A156 WeakPolarHBondContact O-CB 3.31Å; L152-A156 PolarHBondContact O-N 3.24Å; L153-A156 PolarHBondContact O-N 3.44Å; I154-A156 VanDerWaalsContact C-N 3.29Å; I154-A156 PolarHBondContact O-N 2.84Å; A156-A189 HydrophobicContact CB-CB 4.09Å
157	F	82.8	Confident	74.2	Confident	159 Å²	159	79 Å²	79	70%	0.697	44%	0.435	S	S	*	.	H	α-helix	trans	-114	-5.7	-172.3	-66.4	-66.9	0	0	0	114.6	L153 I154 G155 P159	L153-F157 HydrophobicContact CD2-CE2 4.07Å; L153-F157 WeakPolarHBondContact O-CD2 3.42Å; L153-F157 PolarHBondContact O-N 3.19Å; I154-F157 CarbonylContact O-C 3.23Å; I154-F157 PolarHBondContact O-N 3.36Å; I154-F157 VanDerWaalsContact O-N 3.1Å; G155-F157 VanDerWaalsContact C-N 3.33Å; F157-P159 VanDerWaalsContact O-CD 3.26Å; F157-P159 WeakPolarHBondContact O-CD 3.42Å; F157-P159 VanDerWaalsContact O-N 3.16Å
158	V	80.8	Confident	72.3	Confident	37 Å²	37	76.9 Å²	76.9	22%	0.224	43%	0.429	C	S	.	.			trans	-62.3	117.6	176.5	161.2	0	0	0	0	108.6	I154 L160 F192 F484 F486	I154-V158 HydrophobicContact CG2-CG2 3.44Å; I154-V158 VanDerWaalsContact CG2-CG2 3.44Å; I154-V158 WeakPolarHBondContact O-CB 3.4Å; I154-V158 WeakPolarHBondContact O-CG2 3.27Å; I154-V158 PolarHBondContact O-N 3.23Å; V158-L160 PolarHBondContact O-N 2.9Å; V158-F192 HydrophobicContact CG2-CD2 4.36Å; V158-F192 HydrophobicContact CG2-CE2 4.08Å; V158-F484 HydrophobicContact CB-CE1 4.07Å; V158-F484 HydrophobicContact CG1-CD1 3.89Å; V158-F484 HydrophobicContact CG1-CE1 3.61Å; V158-F486 HydrophobicContact CG1-CE1 4.37Å
159	P	65.1	Low	70.6	Confident	87 Å²	87	81.1 Å²	81.1	57%	0.565	45%	0.454	S	S	*	.			trans	-68.7	127.8	175.6	27.9	-31.9	0	0	0	108.7	F157 N161	F157-P159 VanDerWaalsContact O-CD 3.26Å; F157-P159 WeakPolarHBondContact O-CD 3.42Å; F157-P159 VanDerWaalsContact O-N 3.16Å; P159-N161 HydrophobicContact CB-CB 4.38Å; P159-N161 PolarHBondContact O-N 3.3Å
160	L	64.9	Low	68.9	Low	48 Å²	48	82.9 Å²	82.9	25%	0.251	45%	0.454	S	S	.	.			trans	-75.4	25.7	171.9	-65.1	170.1	0	0	0	111.8	V158 L162 K483 F484	V158-L160 PolarHBondContact O-N 2.9Å; L160-L162 WeakPolarHBondContact O-CD1 3.32Å; L160-L162 PolarHBondContact O-N 3.48Å; L160-K483 HydrophobicContact CD2-CG 4.26Å; L160-K483 WeakPolarHBondContact CD2-O 3.34Å; L160-F484 HydrophobicContact CD2-CD1 3.52Å; L160-F484 HydrophobicContact CD2-CE1 3.53Å; L160-F484 HydrophobicContact CD2-CG 4.39Å; L160-F484 HydrophobicContact CD2-CZ 4.4Å
161	N	53.9	Low	67.1	Low	131 Å²	131	80 Å²	80	70%	0.701	44%	0.437	S	S	*	.			trans	-62.3	99.3	-175.8	-70.3	-15.3	0	0	0	109.1	P159	P159-N161 HydrophobicContact CB-CB 4.38Å; P159-N161 PolarHBondContact O-N 3.3Å
162	L	54.2	Low	65.6	Low	35 Å²	35	85.5 Å²	85.5	18%	0.183	46%	0.462	C	S	.	.			trans	-74.1	142.1	168.1	-72.8	114.5	0	0	0	108.8	L160 S164 W171 V174 F178	L160-L162 WeakPolarHBondContact O-CD1 3.32Å; L160-L162 PolarHBondContact O-N 3.48Å; L162-S164 PolarHBondContact O-N 2.93Å; L162-S164 VanDerWaalsContact O-N 3.13Å; L162-W171 HydrophobicContact CD2-CZ3 4.43Å; L162-V174 HydrophobicContact CD2-CG1 3.89Å; L162-F178 HydrophobicContact CD1-CB 3.81Å; L162-F178 HydrophobicContact CD1-CD2 3.48Å; L162-F178 VanDerWaalsContact CD1-CD2 3.48Å; L162-F178 HydrophobicContact CD1-CE2 4.2Å; L162-F178 HydrophobicContact CD1-CG 3.71Å; L162-F178 HydrophobicContact CD2-CD2 3.87Å; L162-F178 HydrophobicContact CD2-CE2 3.78Å; L162-F178 HydrophobicContact CG-CD2 4.3Å
163	P	49.9	Very low	64	Low	53 Å²	53	85.6 Å²	85.6	34%	0.344	46%	0.46	S	S	.	.			trans	-60.9	119.3	178.2	20.2	-27.7	0	0	0	110.8	N165 D335	P163-N165 PolarHBondContact O-N 3.5Å; P163-D335 HydrophobicContact CG-CB 3.74Å
164	S	45.8	Very low	62.5	Low	128 Å²	128	81.2 Å²	81.2	90%	0.895	44%	0.437	S	S	*	.			trans	-74.9	49.5	-175.6	174.5	0	0	0	0	113.2	L162	L162-S164 PolarHBondContact O-N 2.93Å; L162-S164 VanDerWaalsContact O-N 3.13Å
165	N	49.3	Very low	61	Low	138 Å²	138	83.6 Å²	83.6	74%	0.738	44%	0.444	S	S	*	.			trans	-137.9	80.7	-176	-151.8	8.8	0	0	0	112.9	P163	P163-N165 PolarHBondContact O-N 3.5Å
166	K	48.1	Very low	59.5	Low	125 Å²	125	86.7 Å²	86.7	54%	0.543	46%	0.458	S	S	.	.			trans	-178.1	128.5	150	-96.4	151.8	-168.8	-175.9	0	110.4	S168 W171	K166-S168 PolarHBondContact O-N 3.35Å; K166-W171 HydrophobicContact CB-CG 4.1Å; K166-W171 HydrophobicContact CD-CZ2 4.03Å
167	N	51.2	Low	58.2	Low	183 Å²	183	87.5 Å²	87.5	98%	0.979	46%	0.459	S	S	*	.			trans	-75.6	48.7	173.9	-66.4	-16.3	0	0	0	112.2
168	S	56.9	Low	57	Low	43 Å²	43	80.6 Å²	80.6	30%	0.301	43%	0.428	S	S	.	.			trans	-114	142	173.5	78.4	0	0	0	0	111.5	K166 E170 W171	K166-S168 PolarHBondContact O-N 3.35Å; S168-E170 PolarHBondContact O-N 3.13Å; S168-E170 VanDerWaalsContact O-N 3.14Å; S168-W171 WeakPolarHBondContact O-CB 3.48Å; S168-W171 PolarHBondContact O-N 3.04Å
169	T	58.9	Low	55.9	Low	106 Å²	106	85.1 Å²	85.1	65%	0.65	45%	0.447	S	S	*	.	H	α-helix	trans	-57	-23.3	174.9	46.3	0	0	0	0	112.5
170	E	56.4	Low	55.3	Low	84 Å²	84	87.1 Å²	87.1	39%	0.393	45%	0.449	S	S	.	.	H	α-helix	trans	-67.8	-31.3	173.1	-60.5	-172.1	151.8	0	0	112.9	S168 K173 V174	S168-E170 PolarHBondContact O-N 3.13Å; S168-E170 VanDerWaalsContact O-N 3.14Å; E170-K173 PolarHBondContact O-N 3.43Å; E170-V174 WeakPolarHBondContact O-CG2 3.35Å; E170-V174 PolarHBondContact O-N 2.95Å; E170-V174 VanDerWaalsContact O-N 3.11Å
171	W	57.8	Low	54.7	Low	33 Å²	33	85.5 Å²	85.5	13%	0.125	44%	0.44	C	S	.	.	H	α-helix	trans	-72.4	-32.8	178.3	-83.5	99.3	0	0	0	113.2	L162 K166 S168 K173 V174 K175 A332	L162-W171 HydrophobicContact CD2-CZ3 4.43Å; K166-W171 HydrophobicContact CB-CG 4.1Å; K166-W171 HydrophobicContact CD-CZ2 4.03Å; S168-W171 WeakPolarHBondContact O-CB 3.48Å; S168-W171 PolarHBondContact O-N 3.04Å; W171-K173 VanDerWaalsContact C-N 3.31Å; W171-V174 PolarHBondContact O-N 3.47Å; W171-K175 WeakPolarHBondContact O-CB 3.44Å; W171-K175 PolarHBondContact O-N 3.14Å; W171-A332 HydrophobicContact CZ2-CB 4.4Å
172	E	60.4	Low	54.5	Low	146 Å²	146	81.2 Å²	81.2	68%	0.682	43%	0.427	S	S	*	.	H	α-helix	trans	-64.3	-39.4	173.2	-71.4	179.7	164.7	0	0	110.7	K175 F176	E172-K175 PolarHBondContact O-N 3.14Å; E172-F176 VanDerWaalsContact O-CB 3.23Å; E172-F176 WeakPolarHBondContact O-CB 3.38Å; E172-F176 PolarHBondContact O-N 3.04Å
173	K	58.3	Low	54.6	Low	62 Å²	62	85.2 Å²	85.2	27%	0.27	46%	0.458	S	S	.	.	H	α-helix	trans	-63.1	-42.9	173.6	-62.1	-179.6	-176.7	-173.2	0	112.6	E170 W171 F176 L177 D466	E170-K173 PolarHBondContact O-N 3.43Å; W171-K173 VanDerWaalsContact C-N 3.31Å; K173-F176 PolarHBondContact O-N 3.42Å; K173-L177 VanDerWaalsContact O-CG 3.28Å; K173-L177 WeakPolarHBondContact O-CG 3.41Å; K173-L177 PolarHBondContact O-N 3.34Å; K173-D466 IonicContact NZ-OD1 2.74Å; K173-D466 PolarHBondContact NZ-OD1 3.37Å
174	V	57.4	Low	55.4	Low	3 Å²	3	85.2 Å²	85.2	2%	0.018	46%	0.459	C	S	.	.	H	α-helix	trans	-61.5	-50.3	175.4	175.9	0	0	0	0	110.8	L162 E170 W171 F176 L177 F178 F341	L162-V174 HydrophobicContact CD2-CG1 3.89Å; E170-V174 WeakPolarHBondContact O-CG2 3.35Å; E170-V174 PolarHBondContact O-N 2.95Å; E170-V174 VanDerWaalsContact O-N 3.11Å; W171-V174 PolarHBondContact O-N 3.47Å; V174-F176 VanDerWaalsContact C-N 3.3Å; V174-F176 PolarHBondContact O-N 3.39Å; V174-L177 PolarHBondContact O-N 2.89Å; V174-F178 HydrophobicContact CG1-CD2 3.71Å; V174-F178 HydrophobicContact CG1-CE2 3.62Å; V174-F178 WeakPolarHBondContact O-CD2 3.42Å; V174-F178 PolarHBondContact O-N 3.14Å; V174-F341 HydrophobicContact CG2-CE1 3.34Å; V174-F341 HydrophobicContact CG2-CE2 4.28Å; V174-F341 HydrophobicContact CG2-CZ 3.1Å
175	K	57.6	Low	56.6	Low	129 Å²	129	86 Å²	86	56%	0.561	45%	0.449	S	S	*	.	H	α-helix	trans	-59.4	-44.5	179.9	-173.9	-175.7	172.3	-166.9	0	110.7	W171 E172 F178 E179	W171-K175 WeakPolarHBondContact O-CB 3.44Å; W171-K175 PolarHBondContact O-N 3.14Å; E172-K175 PolarHBondContact O-N 3.14Å; K175-F178 CarbonylContact O-C 3.6Å; K175-F178 PolarHBondContact O-N 2.8Å; K175-E179 VanDerWaalsContact O-CB 3.32Å; K175-E179 WeakPolarHBondContact O-CB 3.45Å; K175-E179 PolarHBondContact O-N 2.86Å
176	F	55.8	Low	58	Low	66 Å²	66	81.1 Å²	81.1	29%	0.289	43%	0.43	S	S	.	.	H	α-helix	trans	-59.7	-48.2	176.1	178.3	-92.2	0	0	0	112.3	E172 K173 V174 F178 E179 E180 E469	E172-F176 VanDerWaalsContact O-CB 3.23Å; E172-F176 WeakPolarHBondContact O-CB 3.38Å; E172-F176 PolarHBondContact O-N 3.04Å; K173-F176 PolarHBondContact O-N 3.42Å; V174-F176 VanDerWaalsContact C-N 3.3Å; V174-F176 PolarHBondContact O-N 3.39Å; F176-F178 VanDerWaalsContact C-N 3.26Å; F176-F178 PolarHBondContact O-N 2.84Å; F176-E179 PolarHBondContact O-N 3.49Å; F176-E180 HydrophobicContact CE1-CB 4.44Å; F176-E180 WeakPolarHBondContact CZ-OE2 3.41Å; F176-E180 WeakPolarHBondContact O-CB 3.48Å; F176-E180 PolarHBondContact O-N 3.29Å; F176-E469 HydrophobicContact CD1-CG 3.99Å; F176-E469 WeakPolarHBondContact CD1-OE1 3.1Å; F176-E469 HydrophobicContact CE1-CB 4.31Å; F176-E469 HydrophobicContact CE1-CG 3.56Å; F176-E469 VanDerWaalsContact CE1-OE1 3.29Å; F176-E469 WeakPolarHBondContact CE1-OE1 3.31Å; F176-E469 VanDerWaalsContact CE1-OE2 3.26Å; F176-E469 WeakPolarHBondContact CE1-OE2 3.46Å; F176-E469 WeakPolarHBondContact CE2-OE2 3.21Å; F176-E469 VanDerWaalsContact CG-OE1 3.3Å; F176-E469 WeakPolarHBondContact CG-OE1 3.31Å; F176-E469 HydrophobicContact CZ-CG 4.16Å; F176-E469 WeakPolarHBondContact CZ-OE2 3.45Å
177	L	56.1	Low	59.5	Low	42 Å²	42	75.8 Å²	75.8	22%	0.22	41%	0.408	C	S	.	.	H	α-helix	trans	-53.1	-46.9	174.2	-72.9	168.9	0	0	0	110.3	K173 V174 E179 L181	K173-L177 VanDerWaalsContact O-CG 3.28Å; K173-L177 WeakPolarHBondContact O-CG 3.41Å; K173-L177 PolarHBondContact O-N 3.34Å; V174-L177 PolarHBondContact O-N 2.89Å; L177-E179 VanDerWaalsContact C-N 3.34Å; L177-E179 PolarHBondContact O-N 3.2Å; L177-L181 WeakPolarHBondContact O-CB 3.33Å; L177-L181 WeakPolarHBondContact O-CD1 3.35Å; L177-L181 PolarHBondContact O-N 2.67Å
178	F	57.4	Low	61	Low	14 Å²	14	67.7 Å²	67.7	6%	0.061	37%	0.366	C	S	.	.	H	α-helix	trans	-70.6	-23.8	178.2	-75.5	-71.9	0	0	0	114.8	L162 V174 K175 F176 L181 I339 H482 K483 W485	L162-F178 HydrophobicContact CD1-CB 3.81Å; L162-F178 HydrophobicContact CD1-CD2 3.48Å; L162-F178 VanDerWaalsContact CD1-CD2 3.48Å; L162-F178 HydrophobicContact CD1-CE2 4.2Å; L162-F178 HydrophobicContact CD1-CG 3.71Å; L162-F178 HydrophobicContact CD2-CD2 3.87Å; L162-F178 HydrophobicContact CD2-CE2 3.78Å; L162-F178 HydrophobicContact CG-CD2 4.3Å; V174-F178 HydrophobicContact CG1-CD2 3.71Å; V174-F178 HydrophobicContact CG1-CE2 3.62Å; V174-F178 WeakPolarHBondContact O-CD2 3.42Å; V174-F178 PolarHBondContact O-N 3.14Å; K175-F178 CarbonylContact O-C 3.6Å; K175-F178 PolarHBondContact O-N 2.8Å; F176-F178 VanDerWaalsContact C-N 3.26Å; F176-F178 PolarHBondContact O-N 2.84Å; F178-L181 VanDerWaalsContact O-CB 3.32Å; F178-L181 WeakPolarHBondContact O-CB 3.19Å; F178-I339 HydrophobicContact CE2-CD1 3.96Å; F178-I339 HydrophobicContact CZ-CD1 3.87Å; F178-H482 WeakPolarHBondContact CE1-O 3.15Å; F178-K483 VanDerWaalsContact CD1-O 3.25Å; F178-K483 WeakPolarHBondContact CD1-O 3.06Å; F178-K483 WeakPolarHBondContact CE1-O 3.3Å; F178-W485 HydrophobicContact CZ-CB 4.4Å
179	E	58.6	Low	62.5	Low	131 Å²	131	66.1 Å²	66.1	61%	0.612	36%	0.356	S	S	*	.	H	α-helix	trans	-83.5	-41.1	-179.4	-162.7	159.1	-174.5	0	0	111.8	K175 F176 L177 L181 G182	K175-E179 VanDerWaalsContact O-CB 3.32Å; K175-E179 WeakPolarHBondContact O-CB 3.45Å; K175-E179 PolarHBondContact O-N 2.86Å; F176-E179 PolarHBondContact O-N 3.49Å; L177-E179 VanDerWaalsContact C-N 3.34Å; L177-E179 PolarHBondContact O-N 3.2Å; E179-L181 PolarHBondContact O-N 2.99Å; E179-G182 PolarHBondContact O-N 3.08Å
180	E	53.3	Low	64	Low	130 Å²	130	61.3 Å²	61.3	61%	0.607	33%	0.326	S	S	*	.	H	α-helix	trans	-56.8	-32.6	167.4	-165.7	84.6	-167.5	0	0	111.1	F176 G182	F176-E180 HydrophobicContact CE1-CB 4.44Å; F176-E180 WeakPolarHBondContact CZ-OE2 3.41Å; F176-E180 WeakPolarHBondContact O-CB 3.48Å; F176-E180 PolarHBondContact O-N 3.29Å; E180-G182 PolarHBondContact O-N 3.28Å
181	L	52.1	Low	65.6	Low	13 Å²	13	57.3 Å²	57.3	7%	0.068	31%	0.308	C	S	.	.	T	Hydrogen-bonded Turn	trans	-67.9	-10.7	175.2	-101	80.1	0	0	0	114.1	L177 F178 E179 L479 K483	L177-L181 WeakPolarHBondContact O-CB 3.33Å; L177-L181 WeakPolarHBondContact O-CD1 3.35Å; L177-L181 PolarHBondContact O-N 2.67Å; F178-L181 VanDerWaalsContact O-CB 3.32Å; F178-L181 WeakPolarHBondContact O-CB 3.19Å; E179-L181 PolarHBondContact O-N 2.99Å; L181-L479 HydrophobicContact CD1-CD1 3.32Å; L181-L479 HydrophobicContact CD1-CD2 4.4Å; L181-L479 HydrophobicContact CD1-CG 3.54Å; L181-L479 HydrophobicContact CD2-CG 4.06Å; L181-L479 WeakPolarHBondContact CD2-O 3.19Å; L181-L479 HydrophobicContact CG-CD1 3.85Å; L181-L479 HydrophobicContact CG-CD2 3.97Å; L181-L479 HydrophobicContact CG-CG 3.52Å; L181-K483 HydrophobicContact CB-CD 4.4Å; L181-K483 VanDerWaalsContact CD2-CA 3.49Å; L181-K483 HydrophobicContact CD2-CB 3.6Å; L181-K483 HydrophobicContact CD2-CD 3.99Å; L181-K483 HydrophobicContact CD2-CG 3.66Å; L181-K483 WeakPolarHBondContact O-CE 3.41Å; L181-K483 PolarHBondContact O-NZ 3.04Å
182	G	50	Low	67.2	Low	41 Å²	41	56.6 Å²	56.6	42%	0.423	31%	0.305	S	S	.	.	T	Hydrogen-bonded Turn	trans	-97.7	-3.5	-159.8	0	0	0	0	0	118.8	E179 E180 S184	E179-G182 PolarHBondContact O-N 3.08Å; E180-G182 PolarHBondContact O-N 3.28Å; G182-S184 VanDerWaalsContact C-N 3.34Å; G182-S184 PolarHBondContact O-N 2.66Å
183	S	54.8	Low	68.7	Low	119 Å²	119	49.6 Å²	49.6	83%	0.832	27%	0.273	S	S	*	.	S	Bend	trans	-73.2	-14.3	-162.5	71.9	0	0	0	0	116.9
184	S	66.8	Low	70.4	Confident	54 Å²	54	46.7 Å²	46.7	38%	0.378	26%	0.26	S	S	.	.			trans	-134.2	127.2	176.3	65.2	0	0	0	0	113.7	G182 G186 L187 A188	G182-S184 VanDerWaalsContact C-N 3.34Å; G182-S184 PolarHBondContact O-N 2.66Å; S184-G186 PolarHBondContact O-N 3.5Å; S184-L187 PolarHBondContact O-N 3.12Å; S184-L187 VanDerWaalsContact OG-CB 3.23Å; S184-L187 WeakPolarHBondContact OG-CB 3.25Å; S184-A188 PolarHBondContact O-N 3.09Å
185	H	71.6	Confident	72.1	Confident	145 Å²	145	46.5 Å²	46.5	67%	0.671	26%	0.259	S	S	*	.	H	α-helix	trans	-58.4	-32.5	176.2	-68.4	-73.7	0	0	0	112.5	A188 A189	H185-A188 PolarHBondContact O-N 3.47Å; H185-A189 WeakPolarHBondContact O-CB 3.22Å; H185-A189 PolarHBondContact O-N 2.88Å
186	G	77.6	Confident	73.9	Confident	34 Å²	34	41.2 Å²	41.2	35%	0.351	24%	0.238	S	C	.	.	H	α-helix	trans	-64.9	-39.7	176.7	0	0	0	0	0	113.5	S184 A189 L190	S184-G186 PolarHBondContact O-N 3.5Å; G186-A189 PolarHBondContact O-N 2.88Å; G186-L190 WeakPolarHBondContact O-CB 3.28Å; G186-L190 PolarHBondContact O-N 3.1Å
187	L	79.9	Confident	75.7	Confident	14 Å²	14	38.2 Å²	38.2	7%	0.073	23%	0.225	C	C	.	.	H	α-helix	trans	-66.6	-41.5	175.8	-174.8	103.4	0	0	0	111.2	L95 S184 L190 S191 L479 F480	L95-L187 HydrophobicContact CD1-CD1 3.8Å; S184-L187 PolarHBondContact O-N 3.12Å; S184-L187 VanDerWaalsContact OG-CB 3.23Å; S184-L187 WeakPolarHBondContact OG-CB 3.25Å; L187-L190 PolarHBondContact O-N 3.37Å; L187-S191 VanDerWaalsContact O-CB 3.26Å; L187-S191 WeakPolarHBondContact O-CB 3.42Å; L187-S191 PolarHBondContact O-N 3.05Å; L187-S191 PolarHBondContact O-OG 2.82Å; L187-L479 HydrophobicContact CD2-CD2 3.93Å; L187-F480 HydrophobicContact CD1-CD1 4.43Å; L187-F480 HydrophobicContact CD1-CE1 3.5Å; L187-F480 HydrophobicContact CD1-CE2 4.39Å; L187-F480 HydrophobicContact CD1-CZ 3.49Å; L187-F480 VanDerWaalsContact CD1-CZ 3.49Å; L187-F480 HydrophobicContact CG-CE1 4.08Å
188	A	83.8	Confident	77.6	Confident	13 Å²	13	36.2 Å²	36.2	11%	0.107	22%	0.215	C	C	.	.	H	α-helix	trans	-60.9	-46.5	174.9	0	0	0	0	0	111.9	G155 S184 H185 L190 S191 F192	G155-A188 CarbonylContact O-C 3.49Å; G155-A188 WeakPolarHBondContact O-CB 3.5Å; S184-A188 PolarHBondContact O-N 3.09Å; H185-A188 PolarHBondContact O-N 3.47Å; A188-L190 PolarHBondContact O-N 2.86Å; A188-S191 WeakPolarHBondContact CA-OG 3.44Å; A188-S191 PolarHBondContact O-OG 2.64Å; A188-F192 WeakPolarHBondContact O-CB 3.47Å; A188-F192 PolarHBondContact O-N 2.6Å
189	A	88.4	Confident	79.4	Confident	10 Å²	10	38.2 Å²	38.2	8%	0.083	23%	0.225	C	C	.	.	H	α-helix	trans	-58.2	-50.4	176.2	0	0	0	0	0	112.5	L152 A156 H185 G186 F192 S193	L152-A189 HydrophobicContact CB-CB 4.43Å; L152-A189 HydrophobicContact CD2-CB 4.01Å; L152-A189 VanDerWaalsContact O-CB 3.31Å; L152-A189 WeakPolarHBondContact O-CB 3.44Å; A156-A189 HydrophobicContact CB-CB 4.09Å; H185-A189 WeakPolarHBondContact O-CB 3.22Å; H185-A189 PolarHBondContact O-N 2.88Å; G186-A189 PolarHBondContact O-N 2.88Å; A189-F192 PolarHBondContact O-N 3.47Å; A189-S193 PolarHBondContact O-N 3.4Å; A189-S193 VanDerWaalsContact O-N 3.13Å; A189-S193 PolarHBondContact O-OG 2.95Å
190	L	89.3	Confident	81.1	Confident	5 Å²	5	36.3 Å²	36.3	3%	0.026	22%	0.218	C	C	.	.	H	α-helix	trans	-67.9	-44.5	-177.5	-175.2	146.4	0	0	0	111.9	Y99 Y102 S103 L106 G186 L187 A188 F192 S193 I194 F480	Y99-L190 HydrophobicContact CD2-CD1 3.94Å; Y99-L190 HydrophobicContact CE2-CD1 3.96Å; Y99-L190 HydrophobicContact CG-CD1 4.41Å; Y102-L190 HydrophobicContact CD2-CD2 3.95Å; Y102-L190 HydrophobicContact CG-CD2 4.37Å; S103-L190 VanDerWaalsContact OG-CD1 3.22Å; S103-L190 WeakPolarHBondContact OG-CD1 3.04Å; L106-L190 HydrophobicContact CD1-CG 4.34Å; G186-L190 WeakPolarHBondContact O-CB 3.28Å; G186-L190 PolarHBondContact O-N 3.1Å; L187-L190 PolarHBondContact O-N 3.37Å; A188-L190 PolarHBondContact O-N 2.86Å; L190-F192 VanDerWaalsContact C-N 3.3Å; L190-F192 PolarHBondContact O-N 2.95Å; L190-S193 PolarHBondContact O-N 3.39Å; L190-I194 HydrophobicContact CD2-CG1 4Å; L190-I194 HydrophobicContact CG-CG1 4.4Å; L190-I194 WeakPolarHBondContact O-CB 3.39Å; L190-I194 WeakPolarHBondContact O-CG1 3.33Å; L190-I194 PolarHBondContact O-N 3.46Å; L190-F480 HydrophobicContact CD2-CD1 3.89Å; L190-F480 HydrophobicContact CD2-CE1 3.62Å
191	S	89.7	Confident	83.2	Confident	0 Å²	0	30.1 Å²	30.1	0%	0	19%	0.19	C	C	.	.	H	α-helix	trans	-60.2	-38.5	176.9	56.2	0	0	0	0	112.5	L187 A188 S195 F480 K483	L187-S191 VanDerWaalsContact O-CB 3.26Å; L187-S191 WeakPolarHBondContact O-CB 3.42Å; L187-S191 PolarHBondContact O-N 3.05Å; L187-S191 PolarHBondContact O-OG 2.82Å; A188-S191 WeakPolarHBondContact CA-OG 3.44Å; A188-S191 PolarHBondContact O-OG 2.64Å; S191-S195 WeakPolarHBondContact O-CB 3.44Å; S191-S195 PolarHBondContact O-N 3.41Å; S191-S195 PolarHBondContact O-OG 3.45Å; S191-F480 WeakPolarHBondContact CB-O 3.44Å; S191-K483 WeakPolarHBondContact OG-CD 3.28Å
192	F	91.4	Very high	85.3	Confident	17 Å²	17	30 Å²	30	8%	0.075	19%	0.189	C	C	.	.	H	α-helix	trans	-65.3	-46.8	176.1	-177.5	-89.3	0	0	0	111.7	L151 I154 G155 V158 A188 A189 L190 S195 S196 F484 F486 F487	L151-F192 HydrophobicContact CD2-CE1 3.95Å; L151-F192 VanDerWaalsContact O-CD1 3.25Å; L151-F192 WeakPolarHBondContact O-CD1 3.05Å; I154-F192 HydrophobicContact CB-CE1 3.98Å; I154-F192 HydrophobicContact CB-CZ 4.26Å; I154-F192 HydrophobicContact CG2-CD1 4.32Å; I154-F192 HydrophobicContact CG2-CE1 3.59Å; I154-F192 HydrophobicContact CG2-CE2 3.91Å; I154-F192 HydrophobicContact CG2-CZ 3.36Å; G155-F192 VanDerWaalsContact CA-CG 3.46Å; V158-F192 HydrophobicContact CG2-CD2 4.36Å; V158-F192 HydrophobicContact CG2-CE2 4.08Å; A188-F192 WeakPolarHBondContact O-CB 3.47Å; A188-F192 PolarHBondContact O-N 2.6Å; A189-F192 PolarHBondContact O-N 3.47Å; L190-F192 VanDerWaalsContact C-N 3.3Å; L190-F192 PolarHBondContact O-N 2.95Å; F192-S195 PolarHBondContact O-N 2.92Å; F192-S196 WeakPolarHBondContact O-CB 3.41Å; F192-S196 PolarHBondContact O-N 2.88Å; F192-S196 PolarHBondContact O-OG 3.43Å; F192-F484 HydrophobicContact CB-CD2 4.45Å; F192-F484 HydrophobicContact CB-CE2 3.58Å; F192-F484 HydrophobicContact CB-CZ 3.76Å; F192-F484 HydrophobicContact CD2-CD2 4.33Å; F192-F484 HydrophobicContact CD2-CE1 4.21Å; F192-F484 HydrophobicContact CD2-CE2 4.04Å; F192-F484 AromaticContact CD2-CZ 3.97Å; F192-F484 HydrophobicContact CD2-CZ 3.97Å; F192-F484 HydrophobicContact CG-CE2 4.32Å; F192-F484 HydrophobicContact CG-CZ 4.36Å; F192-F486 HydrophobicContact CD2-CZ 4.23Å; F192-F486 HydrophobicContact CE2-CE2 4.24Å; F192-F486 AromaticContact CE2-CZ 3.82Å; F192-F486 HydrophobicContact CE2-CZ 3.82Å; F192-F487 AromaticContact CD2-CE2 3.67Å; F192-F487 HydrophobicContact CD2-CE2 3.67Å; F192-F487 HydrophobicContact CD2-CZ 4.21Å; F192-F487 AromaticContact CE2-CE2 3.76Å; F192-F487 HydrophobicContact CE2-CE2 3.76Å; F192-F487 AromaticContact CE2-CZ 3.92Å; F192-F487 HydrophobicContact CE2-CZ 3.92Å; F192-F487 HydrophobicContact CG-CE2 4.3Å; F192-F487 HydrophobicContact CZ-CE2 4.45Å; F192-F487 HydrophobicContact CZ-CZ 4.19Å
193	S	93.5	Very high	87.4	Confident	0 Å²	0	33.1 Å²	33.1	0%	0	20%	0.195	C	C	.	.	H	α-helix	trans	-63.1	-43.5	178.9	-66.2	0	0	0	0	111.8	L152 A189 L190 S196 L197	L152-S193 WeakPolarHBondContact CD2-OG 3.36Å; L152-S193 PolarHBondContact N-OG 3.1Å; A189-S193 PolarHBondContact O-N 3.4Å; A189-S193 VanDerWaalsContact O-N 3.13Å; A189-S193 PolarHBondContact O-OG 2.95Å; L190-S193 PolarHBondContact O-N 3.39Å; S193-S196 WeakPolarHBondContact O-CB 3.39Å; S193-S196 PolarHBondContact O-N 3.48Å; S193-L197 PolarHBondContact O-N 2.97Å
194	I	93.6	Very high	89.3	Confident	0 Å²	0	28.1 Å²	28.1	0%	0	16%	0.161	C	C	.	.	H	α-helix	trans	-65.4	-42.9	175.3	-68.3	-61.5	0	0	0	111.3	Y102 L106 L190 S196 L197 T198 L419 L481	Y102-I194 HydrophobicContact CD1-CD1 4.29Å; Y102-I194 HydrophobicContact CD2-CG1 4.06Å; Y102-I194 HydrophobicContact CD2-CG2 4.31Å; Y102-I194 HydrophobicContact CE2-CG2 4.27Å; Y102-I194 HydrophobicContact CG-CD1 3.97Å; Y102-I194 HydrophobicContact CG-CG1 3.94Å; L106-I194 HydrophobicContact CD2-CD1 4.24Å; L106-I194 HydrophobicContact CG-CD1 4.03Å; L190-I194 HydrophobicContact CD2-CG1 4Å; L190-I194 HydrophobicContact CG-CG1 4.4Å; L190-I194 WeakPolarHBondContact O-CB 3.39Å; L190-I194 WeakPolarHBondContact O-CG1 3.33Å; L190-I194 PolarHBondContact O-N 3.46Å; I194-S196 VanDerWaalsContact C-N 3.27Å; I194-S196 PolarHBondContact O-N 3.34Å; I194-L197 PolarHBondContact O-N 3.01Å; I194-L197 VanDerWaalsContact O-N 3.12Å; I194-T198 PolarHBondContact O-N 3.03Å; I194-T198 PolarHBondContact O-OG1 3.37Å; I194-L419 HydrophobicContact CG2-CD1 4.25Å; I194-L419 HydrophobicContact CG2-CD2 4.24Å; I194-L419 HydrophobicContact CG2-CG 4.49Å; I194-L481 HydrophobicContact CG2-CD2 4.35Å
195	S	93.1	Very high	90.7	Very high	0 Å²	0	25.6 Å²	25.6	0%	0	14%	0.143	C	C	.	.	H	α-helix	trans	-61.3	-36.8	175.5	-64.2	0	0	0	0	112.2	S191 F192 T198 L199 F487 Y491	S191-S195 WeakPolarHBondContact O-CB 3.44Å; S191-S195 PolarHBondContact O-N 3.41Å; S191-S195 PolarHBondContact O-OG 3.45Å; F192-S195 PolarHBondContact O-N 2.92Å; S195-T198 VanDerWaalsContact C-OG1 3.26Å; S195-T198 WeakPolarHBondContact CA-OG1 3.38Å; S195-T198 PolarHBondContact O-N 3.36Å; S195-T198 PolarHBondContact O-OG1 2.9Å; S195-L199 PolarHBondContact O-N 2.87Å; S195-F487 VanDerWaalsContact CB-CE2 3.46Å; S195-Y491 PolarHBondContact O-OH 3.42Å
196	S	94.4	Very high	91.9	Very high	17 Å²	17	19.6 Å²	19.6	12%	0.119	12%	0.116	C	C	.	.	H	α-helix	trans	-65.3	-43	173.8	-57.5	0	0	0	0	111.5	F192 S193 I194 L199 I200 F487	F192-S196 WeakPolarHBondContact O-CB 3.41Å; F192-S196 PolarHBondContact O-N 2.88Å; F192-S196 PolarHBondContact O-OG 3.43Å; S193-S196 WeakPolarHBondContact O-CB 3.39Å; S193-S196 PolarHBondContact O-N 3.48Å; I194-S196 VanDerWaalsContact C-N 3.27Å; I194-S196 PolarHBondContact O-N 3.34Å; S196-L199 WeakPolarHBondContact O-CB 3.44Å; S196-L199 PolarHBondContact O-N 2.92Å; S196-I200 PolarHBondContact O-N 2.73Å; S196-F487 WeakPolarHBondContact OG-CZ 3.43Å
197	L	95	Very high	92.6	Very high	4 Å²	4	21.2 Å²	21.2	2%	0.021	12%	0.119	C	C	.	.	H	α-helix	trans	-66.2	-39	175.7	-71.8	-175.5	0	0	0	112.7	I105 L106 V109 F110 S193 I194 L199 I200 G201 L416 L419	I105-L197 HydrophobicContact CG2-CD1 4.47Å; L106-L197 HydrophobicContact CD2-CD1 3.65Å; L106-L197 HydrophobicContact CD2-CG 4.45Å; V109-L197 HydrophobicContact CB-CD1 4.42Å; V109-L197 HydrophobicContact CG1-CD1 4.36Å; V109-L197 HydrophobicContact CG1-CD2 3.96Å; V109-L197 HydrophobicContact CG2-CD1 4.36Å; F110-L197 HydrophobicContact CE2-CD1 4.07Å; F110-L197 HydrophobicContact CE2-CD2 3.9Å; F110-L197 HydrophobicContact CE2-CG 4.2Å; F110-L197 HydrophobicContact CZ-CD2 3.78Å; F110-L197 HydrophobicContact CZ-CG 4.46Å; S193-L197 PolarHBondContact O-N 2.97Å; I194-L197 PolarHBondContact O-N 3.01Å; I194-L197 VanDerWaalsContact O-N 3.12Å; L197-L199 VanDerWaalsContact C-N 3.28Å; L197-L199 PolarHBondContact O-N 3.13Å; L197-I200 HydrophobicContact CD2-CD1 4.4Å; L197-I200 PolarHBondContact O-N 3.44Å; L197-G201 PolarHBondContact O-N 2.82Å; L197-L416 HydrophobicContact CB-CD2 3.99Å; L197-L416 HydrophobicContact CD2-CD2 3.97Å; L197-L416 HydrophobicContact CG-CD2 4.4Å; L197-L419 HydrophobicContact CB-CD2 3.78Å
198	T	94.4	Very high	93.3	Very high	0 Å²	0	21.3 Å²	21.3	0%	0	12%	0.119	C	C	.	.	H	α-helix	trans	-66.9	-29	174.7	40.4	0	0	0	0	112.6	I194 S195 G201 M202 L419 L481 Y491	I194-T198 PolarHBondContact O-N 3.03Å; I194-T198 PolarHBondContact O-OG1 3.37Å; S195-T198 VanDerWaalsContact C-OG1 3.26Å; S195-T198 WeakPolarHBondContact CA-OG1 3.38Å; S195-T198 PolarHBondContact O-N 3.36Å; S195-T198 PolarHBondContact O-OG1 2.9Å; T198-G201 CarbonylContact O-C 3.54Å; T198-G201 PolarHBondContact O-N 2.86Å; T198-M202 WeakPolarHBondContact O-CB 3.23Å; T198-M202 PolarHBondContact O-N 2.8Å; T198-L419 HydrophobicContact CG2-CB 4.17Å; T198-L419 HydrophobicContact CG2-CD2 3.66Å; T198-L419 HydrophobicContact CG2-CG 3.44Å; T198-L419 VanDerWaalsContact CG2-CG 3.44Å; T198-L481 HydrophobicContact CG2-CD2 4.11Å; T198-Y491 PolarHBondContact OG1-OH 3.3Å
199	L	95.3	Very high	93.9	Very high	55 Å²	55	20.7 Å²	20.7	29%	0.288	11%	0.114	S	C	.	.	H	α-helix	trans	-65.3	-42.2	171.5	-172	72.2	0	0	0	111.3	S195 S196 L197 G201 M202 L203 F487 A490 Y491	S195-L199 PolarHBondContact O-N 2.87Å; S196-L199 WeakPolarHBondContact O-CB 3.44Å; S196-L199 PolarHBondContact O-N 2.92Å; L197-L199 VanDerWaalsContact C-N 3.28Å; L197-L199 PolarHBondContact O-N 3.13Å; L199-G201 VanDerWaalsContact C-N 3.34Å; L199-M202 HydrophobicContact CD1-CE 3.61Å; L199-M202 WeakPolarHBondContact O-CB 3.47Å; L199-M202 PolarHBondContact O-N 3.05Å; L199-L203 PolarHBondContact O-N 2.93Å; L199-F487 HydrophobicContact CD2-CE1 4.3Å; L199-A490 HydrophobicContact CD1-CB 3.78Å; L199-Y491 HydrophobicContact CB-CE1 4.35Å; L199-Y491 HydrophobicContact CD1-CD1 4.45Å; L199-Y491 HydrophobicContact CD1-CE1 4.22Å
200	I	95.6	Very high	94.2	Very high	91 Å²	91	20.2 Å²	20.2	47%	0.467	11%	0.11	S	C	.	.	H	α-helix	trans	-64.9	-42.4	172.5	-58.5	169.7	0	0	0	110.1	S196 L197 M202 L203 A204 L416	S196-I200 PolarHBondContact O-N 2.73Å; L197-I200 HydrophobicContact CD2-CD1 4.4Å; L197-I200 PolarHBondContact O-N 3.44Å; I200-M202 VanDerWaalsContact C-N 3.27Å; I200-M202 PolarHBondContact O-N 2.92Å; I200-L203 WeakPolarHBondContact O-CB 3.35Å; I200-L203 PolarHBondContact O-N 3.35Å; I200-A204 PolarHBondContact O-N 2.87Å; I200-A204 VanDerWaalsContact O-N 3.08Å; I200-L416 HydrophobicContact CG2-CD1 3.9Å
201	G	96.1	Very high	94.4	Very high	0 Å²	0	21.4 Å²	21.4	0%	0	11%	0.114	C	C	.	.	H	α-helix	trans	-59.1	-35.5	174.4	0	0	0	0	0	113.4	L197 T198 L199 A204 A205 L416	L197-G201 PolarHBondContact O-N 2.82Å; T198-G201 CarbonylContact O-C 3.54Å; T198-G201 PolarHBondContact O-N 2.86Å; L199-G201 VanDerWaalsContact C-N 3.34Å; G201-A204 PolarHBondContact O-N 2.95Å; G201-A205 WeakPolarHBondContact O-CB 3.17Å; G201-A205 PolarHBondContact O-N 3.47Å; G201-L416 WeakPolarHBondContact CA-O 3.26Å
202	M	95.9	Very high	94.7	Very high	12 Å²	12	21.4 Å²	21.4	6%	0.059	11%	0.114	C	C	.	.	H	α-helix	trans	-63.7	-45.8	174.5	-178.2	-175	76.5	0	0	111.3	T198 L199 I200 A204 A205 I206 Y491 G494	T198-M202 WeakPolarHBondContact O-CB 3.23Å; T198-M202 PolarHBondContact O-N 2.8Å; L199-M202 HydrophobicContact CD1-CE 3.61Å; L199-M202 WeakPolarHBondContact O-CB 3.47Å; L199-M202 PolarHBondContact O-N 3.05Å; I200-M202 VanDerWaalsContact C-N 3.27Å; I200-M202 PolarHBondContact O-N 2.92Å; M202-A204 VanDerWaalsContact C-N 3.3Å; M202-A204 PolarHBondContact O-N 3.44Å; M202-A205 PolarHBondContact O-N 3.1Å; M202-A205 VanDerWaalsContact O-N 3.14Å; M202-I206 HydrophobicContact CE-CD1 4.5Å; M202-I206 HydrophobicContact CG-CD1 3.86Å; M202-I206 HydrophobicContact CG-CG1 4.42Å; M202-I206 VanDerWaalsContact O-CG1 3.26Å; M202-I206 WeakPolarHBondContact O-CG1 3.39Å; M202-I206 PolarHBondContact O-N 3.27Å; M202-Y491 HydrophobicContact SD-CD1 3.69Å; M202-G494 VanDerWaalsContact SD-CA 3.59Å
203	L	95.3	Very high	94.8	Very high	106 Å²	106	20.6 Å²	20.6	56%	0.555	11%	0.111	S	C	*	.	H	α-helix	trans	-59.1	-45.1	175.6	-62.4	177.1	0	0	0	110.7	L199 I200 A205 I206 T207	L199-L203 PolarHBondContact O-N 2.93Å; I200-L203 WeakPolarHBondContact O-CB 3.35Å; I200-L203 PolarHBondContact O-N 3.35Å; L203-A205 VanDerWaalsContact C-N 3.33Å; L203-A205 PolarHBondContact O-N 2.93Å; L203-I206 PolarHBondContact O-N 3.33Å; L203-T207 WeakPolarHBondContact O-CG2 3.33Å; L203-T207 PolarHBondContact O-N 2.88Å; L203-T207 PolarHBondContact O-OG1 3.29Å
204	A	94.7	Very high	94.8	Very high	14 Å²	14	20.8 Å²	20.8	12%	0.116	11%	0.112	C	C	.	.	H	α-helix	trans	-62.8	-37.2	175.5	0	0	0	0	0	112.7	I200 G201 M202 T207 Y208 I413 I417	I200-A204 PolarHBondContact O-N 2.87Å; I200-A204 VanDerWaalsContact O-N 3.08Å; G201-A204 PolarHBondContact O-N 2.95Å; M202-A204 VanDerWaalsContact C-N 3.3Å; M202-A204 PolarHBondContact O-N 3.44Å; A204-T207 WeakPolarHBondContact CA-OG1 3.48Å; A204-T207 PolarHBondContact O-N 3.08Å; A204-T207 PolarHBondContact O-OG1 3.18Å; A204-Y208 HydrophobicContact CB-CD2 4.39Å; A204-Y208 VanDerWaalsContact O-CB 3.3Å; A204-Y208 WeakPolarHBondContact O-CB 3.41Å; A204-Y208 VanDerWaalsContact O-CD2 3.3Å; A204-Y208 WeakPolarHBondContact O-CD2 3.1Å; A204-Y208 PolarHBondContact O-N 3.25Å; A204-I413 HydrophobicContact CB-CG2 4.25Å; A204-I417 HydrophobicContact CB-CD1 4.14Å; A204-I417 HydrophobicContact CB-CG1 3.78Å
205	A	96.1	Very high	94.6	Very high	0 Å²	0	20.8 Å²	20.8	0%	0	11%	0.112	C	C	.	.	I	π-helix	trans	-71	-40.7	178.1	0	0	0	0	0	112	G201 M202 L203 T207 T209 A210	G201-A205 WeakPolarHBondContact O-CB 3.17Å; G201-A205 PolarHBondContact O-N 3.47Å; M202-A205 PolarHBondContact O-N 3.1Å; M202-A205 VanDerWaalsContact O-N 3.14Å; L203-A205 VanDerWaalsContact C-N 3.33Å; L203-A205 PolarHBondContact O-N 2.93Å; A205-T207 VanDerWaalsContact C-N 3.31Å; A205-T207 PolarHBondContact O-N 2.88Å; A205-T209 VanDerWaalsContact CA-OG1 3.31Å; A205-T209 WeakPolarHBondContact CA-OG1 3.42Å; A205-T209 CarbonylContact O-C 3.57Å; A205-T209 VanDerWaalsContact O-CA 3.29Å; A205-T209 WeakPolarHBondContact O-CA 3.43Å; A205-T209 WeakPolarHBondContact O-CB 3.17Å; A205-T209 PolarHBondContact O-N 2.94Å; A205-T209 PolarHBondContact O-OG1 3.36Å; A205-A210 PolarHBondContact O-N 3.18Å
206	I	95.8	Very high	94.5	Very high	20 Å²	20	22 Å²	22	10%	0.103	12%	0.118	C	C	.	.	I	π-helix	trans	-59.4	-44.2	173.6	-68.1	163.1	0	0	0	110	M202 L203 A210 A497 F498 V501	M202-I206 HydrophobicContact CE-CD1 4.5Å; M202-I206 HydrophobicContact CG-CD1 3.86Å; M202-I206 HydrophobicContact CG-CG1 4.42Å; M202-I206 VanDerWaalsContact O-CG1 3.26Å; M202-I206 WeakPolarHBondContact O-CG1 3.39Å; M202-I206 PolarHBondContact O-N 3.27Å; L203-I206 PolarHBondContact O-N 3.33Å; I206-A210 VanDerWaalsContact O-CB 3.29Å; I206-A210 WeakPolarHBondContact O-CB 3.45Å; I206-A497 HydrophobicContact CD1-CB 4.02Å; I206-F498 HydrophobicContact CG1-CB 4.02Å; I206-F498 HydrophobicContact CG1-CD2 4.26Å; I206-V501 HydrophobicContact CG2-CB 4.22Å; I206-V501 HydrophobicContact CG2-CG2 3.7Å; I206-V501 WeakPolarHBondContact O-CG1 3.48Å
207	T	93.3	Very high	94.3	Very high	67 Å²	67	21.3 Å²	21.3	41%	0.411	11%	0.113	S	C	.	.	I	π-helix	trans	-74.2	-46.2	-179.1	55.1	0	0	0	0	113.1	L203 A204 A205	L203-T207 WeakPolarHBondContact O-CG2 3.33Å; L203-T207 PolarHBondContact O-N 2.88Å; L203-T207 PolarHBondContact O-OG1 3.29Å; A204-T207 WeakPolarHBondContact CA-OG1 3.48Å; A204-T207 PolarHBondContact O-N 3.08Å; A204-T207 PolarHBondContact O-OG1 3.18Å; A205-T207 VanDerWaalsContact C-N 3.31Å; A205-T207 PolarHBondContact O-N 2.88Å
208	Y	94.9	Very high	94.1	Very high	16 Å²	16	22.2 Å²	22.2	6%	0.063	12%	0.118	C	C	.	.	I	π-helix	trans	-100.6	-46.6	-169.3	-63.9	-59.9	0	0	0	113.4	A204 G212 G381 I382 I385 G386 I387 W388 I413	A204-Y208 HydrophobicContact CB-CD2 4.39Å; A204-Y208 VanDerWaalsContact O-CB 3.3Å; A204-Y208 WeakPolarHBondContact O-CB 3.41Å; A204-Y208 VanDerWaalsContact O-CD2 3.3Å; A204-Y208 WeakPolarHBondContact O-CD2 3.1Å; A204-Y208 PolarHBondContact O-N 3.25Å; Y208-G212 WeakPolarHBondContact O-CA 3.36Å; Y208-G212 PolarHBondContact O-N 2.96Å; Y208-G381 WeakPolarHBondContact O-CA 3.08Å; Y208-I382 HydrophobicContact CD1-CB 4.14Å; Y208-I382 HydrophobicContact CD1-CG1 3.67Å; Y208-I382 HydrophobicContact CD2-CG1 3.91Å; Y208-I382 HydrophobicContact CE1-CB 4.42Å; Y208-I382 HydrophobicContact CE1-CG1 4.19Å; Y208-I382 HydrophobicContact CE1-CG2 4.39Å; Y208-I382 HydrophobicContact CE2-CG1 4.41Å; Y208-I382 HydrophobicContact CG-CB 4.46Å; Y208-I382 HydrophobicContact CG-CG1 3.5Å; Y208-I385 HydrophobicContact CD1-CB 4.43Å; Y208-I385 HydrophobicContact CD1-CD1 4.25Å; Y208-I385 HydrophobicContact CE1-CB 4.12Å; Y208-I385 HydrophobicContact CE1-CG2 4.03Å; Y208-G386 VanDerWaalsContact CE1-O 3.23Å; Y208-G386 WeakPolarHBondContact CE1-O 3.33Å; Y208-G386 PolarHBondContact OH-O 3.27Å; Y208-I387 WeakPolarHBondContact OH-CA 3.22Å; Y208-W388 PolarHBondContact OH-N 2.88Å; Y208-I413 HydrophobicContact CD2-CG2 4.1Å; Y208-I413 HydrophobicContact CE2-CG2 4.18Å
209	T	95.9	Very high	93.7	Very high	0 Å²	0	24.5 Å²	24.5	0%	0	13%	0.13	C	C	.	.	I	π-helix	trans	-70.7	-47.7	-177.5	-44.9	0	0	0	0	110.8	A205 Y211 G212 M213 F374 S378 F498	A205-T209 VanDerWaalsContact CA-OG1 3.31Å; A205-T209 WeakPolarHBondContact CA-OG1 3.42Å; A205-T209 CarbonylContact O-C 3.57Å; A205-T209 VanDerWaalsContact O-CA 3.29Å; A205-T209 WeakPolarHBondContact O-CA 3.43Å; A205-T209 WeakPolarHBondContact O-CB 3.17Å; A205-T209 PolarHBondContact O-N 2.94Å; A205-T209 PolarHBondContact O-OG1 3.36Å; T209-Y211 PolarHBondContact O-N 3.43Å; T209-G212 CarbonylContact O-C 3.57Å; T209-G212 WeakPolarHBondContact O-CA 3.25Å; T209-G212 PolarHBondContact O-N 3.4Å; T209-G212 VanDerWaalsContact O-N 3.08Å; T209-M213 HydrophobicContact CG2-CG 4.41Å; T209-M213 VanDerWaalsContact O-CG 3.31Å; T209-M213 WeakPolarHBondContact O-CG 3.23Å; T209-M213 PolarHBondContact O-N 2.79Å; T209-F374 HydrophobicContact CG2-CD1 3.64Å; T209-F374 HydrophobicContact CG2-CE1 4.38Å; T209-S378 WeakPolarHBondContact CB-OG 3.44Å; T209-S378 WeakPolarHBondContact CG2-OG 3.26Å; T209-S378 PolarHBondContact OG1-OG 3.35Å; T209-F498 HydrophobicContact CG2-CE2 4.3Å; T209-F498 HydrophobicContact CG2-CZ 4.41Å
210	A	95.4	Very high	93.3	Very high	0 Å²	0	24.5 Å²	24.5	0%	0	13%	0.13	C	C	.	.	H	α-helix	trans	-60.9	-46.5	-178.9	0	0	0	0	0	112.6	A205 I206 S214 F498 V501 F502	A205-A210 PolarHBondContact O-N 3.18Å; I206-A210 VanDerWaalsContact O-CB 3.29Å; I206-A210 WeakPolarHBondContact O-CB 3.45Å; A210-S214 PolarHBondContact O-OG 3.02Å; A210-F498 HydrophobicContact CB-CD2 3.79Å; A210-F498 HydrophobicContact CB-CE2 3.77Å; A210-F498 HydrophobicContact CB-CG 4.23Å; A210-F498 HydrophobicContact CB-CZ 4.21Å; A210-V501 HydrophobicContact CB-CB 4.16Å; A210-V501 HydrophobicContact CB-CG1 4.01Å; A210-F502 HydrophobicContact CB-CB 4.38Å
211	Y	93.9	Very high	92.9	Very high	31 Å²	31	22.5 Å²	22.5	12%	0.122	12%	0.12	C	C	.	.	H	α-helix	trans	-66.5	-37.9	172.6	176.9	-101.4	0	0	0	112	T209 M213 S214 A215 N384 I385	T209-Y211 PolarHBondContact O-N 3.43Å; Y211-M213 PolarHBondContact O-N 3.08Å; Y211-S214 PolarHBondContact O-N 3.38Å; Y211-S214 PolarHBondContact O-OG 3.13Å; Y211-A215 HydrophobicContact CD1-CB 4.15Å; Y211-A215 HydrophobicContact CE1-CB 3.76Å; Y211-A215 HydrophobicContact CE2-CB 4.25Å; Y211-A215 WeakPolarHBondContact O-CB 3.43Å; Y211-A215 PolarHBondContact O-N 3.31Å; Y211-N384 HydrophobicContact CE1-CB 3.8Å; Y211-I385 HydrophobicContact CD1-CD1 3.41Å; Y211-I385 VanDerWaalsContact CD1-CD1 3.41Å; Y211-I385 HydrophobicContact CD1-CG1 3.74Å; Y211-I385 HydrophobicContact CE1-CD1 4Å; Y211-I385 HydrophobicContact CE1-CG1 3.78Å; Y211-I385 HydrophobicContact CG-CD1 3.81Å; Y211-I385 HydrophobicContact CG-CG1 4.49Å
212	G	94.1	Very high	92.4	Very high	0 Å²	0	24.9 Å²	24.9	0%	0	13%	0.13	C	C	.	.	H	α-helix	trans	-60.6	-41.2	176.5	0	0	0	0	0	113.7	Y208 T209 S214 L216 T377	Y208-G212 WeakPolarHBondContact O-CA 3.36Å; Y208-G212 PolarHBondContact O-N 2.96Å; T209-G212 CarbonylContact O-C 3.57Å; T209-G212 WeakPolarHBondContact O-CA 3.25Å; T209-G212 PolarHBondContact O-N 3.4Å; T209-G212 VanDerWaalsContact O-N 3.08Å; G212-S214 VanDerWaalsContact C-N 3.27Å; G212-S214 PolarHBondContact O-N 3.09Å; G212-L216 WeakPolarHBondContact O-CB 3.47Å; G212-L216 PolarHBondContact O-N 2.92Å; G212-T377 VanDerWaalsContact CA-O 3.25Å; G212-T377 WeakPolarHBondContact CA-O 3.41Å
213	M	93.7	Very high	91.6	Very high	0 Å²	0	25.1 Å²	25.1	0%	0	14%	0.136	C	C	.	.	H	α-helix	trans	-63.7	-30.8	178.2	-72.4	-168.7	-40.7	0	0	112.6	T209 Y211 P217 I317 Y373 F374 T377 F498 F502	T209-M213 HydrophobicContact CG2-CG 4.41Å; T209-M213 VanDerWaalsContact O-CG 3.31Å; T209-M213 WeakPolarHBondContact O-CG 3.23Å; T209-M213 PolarHBondContact O-N 2.79Å; Y211-M213 PolarHBondContact O-N 3.08Å; M213-P217 WeakPolarHBondContact O-CD 3.12Å; M213-P217 WeakPolarHBondContact O-CG 3.46Å; M213-I317 HydrophobicContact CE-CD1 4.1Å; M213-Y373 HydrophobicContact CG-CE1 3.97Å; M213-Y373 HydrophobicContact SD-CE1 3.93Å; M213-F374 HydrophobicContact SD-CD1 4.32Å; M213-F374 HydrophobicContact SD-CE1 3.81Å; M213-T377 HydrophobicContact CB-CG2 4.38Å; M213-T377 HydrophobicContact CG-CG2 3.87Å; M213-F498 HydrophobicContact CE-CD1 4.43Å; M213-F498 HydrophobicContact CE-CE1 3.27Å; M213-F498 HydrophobicContact CE-CE2 4.42Å; M213-F498 HydrophobicContact CE-CZ 3.26Å; M213-F498 HydrophobicContact SD-CE1 4.29Å; M213-F498 HydrophobicContact SD-CZ 3.9Å; M213-F502 HydrophobicContact CB-CD2 4.04Å; M213-F502 HydrophobicContact CB-CE2 4.03Å; M213-F502 HydrophobicContact CE-CD2 3.71Å; M213-F502 HydrophobicContact CE-CE2 4.27Å; M213-F502 HydrophobicContact CE-CG 4.39Å
214	S	93.3	Very high	90.8	Very high	3 Å²	3	23.7 Å²	23.7	2%	0.021	13%	0.132	C	C	.	.	H	α-helix	trans	-88.9	-43.3	176	55.4	0	0	0	0	112.2	A210 Y211 G212 P217 L218 G505 L506	A210-S214 PolarHBondContact O-OG 3.02Å; Y211-S214 PolarHBondContact O-N 3.38Å; Y211-S214 PolarHBondContact O-OG 3.13Å; G212-S214 VanDerWaalsContact C-N 3.27Å; G212-S214 PolarHBondContact O-N 3.09Å; S214-P217 WeakPolarHBondContact O-CD 3.47Å; S214-P217 WeakPolarHBondContact O-CG 3.22Å; S214-L218 WeakPolarHBondContact O-CD1 3.19Å; S214-L218 WeakPolarHBondContact O-CG 3.3Å; S214-G505 PolarHBondContact OG-O 2.99Å; S214-L506 PolarHBondContact OG-N 2.96Å
215	A	90.5	Very high	90	Very high	0 Å²	0	27.2 Å²	27.2	0%	0	14%	0.142	C	C	.	.	H	α-helix	trans	-72.6	-38.2	-176.9	0	0	0	0	0	113.6	Y211 N219 S509	Y211-A215 HydrophobicContact CD1-CB 4.15Å; Y211-A215 HydrophobicContact CE1-CB 3.76Å; Y211-A215 HydrophobicContact CE2-CB 4.25Å; Y211-A215 WeakPolarHBondContact O-CB 3.43Å; Y211-A215 PolarHBondContact O-N 3.31Å; A215-N219 WeakPolarHBondContact O-CB 3.13Å; A215-N219 PolarHBondContact O-N 3.49Å; A215-N219 PolarHBondContact O-ND2 2.81Å; A215-S509 WeakPolarHBondContact CA-OG 3.3Å
216	L	90.7	Very high	89.2	Confident	26 Å²	26	32.5 Å²	32.5	14%	0.136	17%	0.17	C	C	.	.	H	α-helix	trans	-57	-56.1	-178.9	179.2	152.9	0	0	0	112.5	G212 N219 L220 F309 T377 A380	G212-L216 WeakPolarHBondContact O-CB 3.47Å; G212-L216 PolarHBondContact O-N 2.92Å; L216-N219 PolarHBondContact O-N 2.89Å; L216-L220 HydrophobicContact CD2-CD1 3.67Å; L216-L220 HydrophobicContact CG-CD1 4.38Å; L216-L220 WeakPolarHBondContact O-CG 3.35Å; L216-L220 PolarHBondContact O-N 3.07Å; L216-L220 VanDerWaalsContact O-N 3.1Å; L216-F309 HydrophobicContact CD2-CB 4.27Å; L216-F309 HydrophobicContact CD2-CD2 3.6Å; L216-F309 HydrophobicContact CD2-CE2 4.06Å; L216-F309 HydrophobicContact CD2-CG 3.97Å; L216-T377 HydrophobicContact CD1-CG2 4.34Å; L216-A380 HydrophobicContact CB-CB 3.9Å; L216-A380 HydrophobicContact CD1-CB 3.72Å; L216-A380 HydrophobicContact CG-CB 4.19Å
217	P	91.3	Very high	88.4	Confident	2 Å²	2	32.1 Å²	32.1	1%	0.013	17%	0.17	C	C	.	.	H	α-helix	trans	-65.2	-41.2	-179.4	19.7	-29.9	0	0	0	112.8	M213 S214 N219 L220 I221 G306 F309 I310	M213-P217 WeakPolarHBondContact O-CD 3.12Å; M213-P217 WeakPolarHBondContact O-CG 3.46Å; S214-P217 WeakPolarHBondContact O-CD 3.47Å; S214-P217 WeakPolarHBondContact O-CG 3.22Å; P217-N219 VanDerWaalsContact C-N 3.32Å; P217-N219 PolarHBondContact O-N 3.26Å; P217-L220 WeakPolarHBondContact O-CB 3.41Å; P217-L220 PolarHBondContact O-N 3.43Å; P217-L220 VanDerWaalsContact O-N 3.09Å; P217-I221 WeakPolarHBondContact O-CG1 3.37Å; P217-I221 PolarHBondContact O-N 3.12Å; P217-G306 VanDerWaalsContact CB-O 3.28Å; P217-G306 WeakPolarHBondContact CB-O 3.4Å; P217-F309 HydrophobicContact CB-CB 3.95Å; P217-F309 HydrophobicContact CG-CB 4.47Å; P217-I310 HydrophobicContact CB-CD1 4.2Å; P217-I310 HydrophobicContact CB-CG1 3.43Å; P217-I310 VanDerWaalsContact CB-CG1 3.43Å; P217-I310 HydrophobicContact CG-CG1 3.8Å
218	L	89.1	Confident	87.8	Confident	23 Å²	23	30.6 Å²	30.6	12%	0.12	16%	0.164	C	C	.	.	H	α-helix	trans	-66.2	-36.8	-179.4	-70.1	171.9	0	0	0	111.8	S214 L220 I221 K222 I310	S214-L218 WeakPolarHBondContact O-CD1 3.19Å; S214-L218 WeakPolarHBondContact O-CG 3.3Å; L218-L220 VanDerWaalsContact C-N 3.33Å; L218-I221 PolarHBondContact O-N 3.42Å; L218-K222 VanDerWaalsContact O-CB 3.28Å; L218-K222 WeakPolarHBondContact O-CB 3.27Å; L218-K222 WeakPolarHBondContact O-CG 3.34Å; L218-K222 PolarHBondContact O-N 3.16Å; L218-I310 HydrophobicContact CD2-CD1 4.13Å
219	N	86.9	Confident	87.3	Confident	49 Å²	49	36.5 Å²	36.5	26%	0.262	19%	0.187	S	C	.	.	H	α-helix	trans	-66.4	-33.5	172.1	-74.6	-47.2	0	0	0	112.2	A215 L216 P217 G223 N384	A215-N219 WeakPolarHBondContact O-CB 3.13Å; A215-N219 PolarHBondContact O-N 3.49Å; A215-N219 PolarHBondContact O-ND2 2.81Å; L216-N219 PolarHBondContact O-N 2.89Å; P217-N219 VanDerWaalsContact C-N 3.32Å; P217-N219 PolarHBondContact O-N 3.26Å; N219-G223 WeakPolarHBondContact O-CA 3.46Å; N219-G223 PolarHBondContact O-N 3.46Å; N219-N384 PolarHBondContact ND2-ND2 3.3Å
220	L	86.6	Confident	86.7	Confident	54 Å²	54	36.9 Å²	36.9	28%	0.283	19%	0.189	S	C	.	.	H	α-helix	trans	-68.4	-40.4	174.9	-75.5	164.1	0	0	0	112.1	L216 P217 L218 F309	L216-L220 HydrophobicContact CD2-CD1 3.67Å; L216-L220 HydrophobicContact CG-CD1 4.38Å; L216-L220 WeakPolarHBondContact O-CG 3.35Å; L216-L220 PolarHBondContact O-N 3.07Å; L216-L220 VanDerWaalsContact O-N 3.1Å; P217-L220 WeakPolarHBondContact O-CB 3.41Å; P217-L220 PolarHBondContact O-N 3.43Å; P217-L220 VanDerWaalsContact O-N 3.09Å; L218-L220 VanDerWaalsContact C-N 3.33Å; L220-F309 HydrophobicContact CD1-CD2 3.87Å; L220-F309 HydrophobicContact CD1-CE2 4.18Å
221	I	87.5	Confident	86.2	Confident	50 Å²	50	39.5 Å²	39.5	26%	0.256	20%	0.199	S	C	.	.	H	α-helix	trans	-71.3	-54.7	179.4	-64.4	167.9	0	0	0	110.7	P217 L218 G223 R299 I307 I310	P217-I221 WeakPolarHBondContact O-CG1 3.37Å; P217-I221 PolarHBondContact O-N 3.12Å; L218-I221 PolarHBondContact O-N 3.42Å; I221-G223 VanDerWaalsContact C-N 3.32Å; I221-G223 PolarHBondContact O-N 3.07Å; I221-R299 PolarHBondContact O-NH2 3.27Å; I221-I307 HydrophobicContact CD1-CG1 4.29Å; I221-I310 HydrophobicContact CD1-CD1 3.53Å; I221-I310 HydrophobicContact CD1-CG1 4.45Å
222	K	85.4	Confident	86	Confident	49 Å²	49	43.5 Å²	43.5	21%	0.213	22%	0.222	C	C	.	.	H	α-helix	trans	-64.5	-38.5	-179.5	-70.9	-179.9	174	-174.2	0	112.2	L218 R299 S509 C510 K512 K514	L218-K222 VanDerWaalsContact O-CB 3.28Å; L218-K222 WeakPolarHBondContact O-CB 3.27Å; L218-K222 WeakPolarHBondContact O-CG 3.34Å; L218-K222 PolarHBondContact O-N 3.16Å; K222-R299 PolarHBondContact O-NH2 2.96Å; K222-S509 PolarHBondContact NZ-O 2.92Å; K222-C510 VanDerWaalsContact NZ-C 3.33Å; K222-C510 PolarHBondContact NZ-O 2.85Å; K222-K512 PolarHBondContact NZ-O 2.78Å; K222-K514 HydrophobicContact CB-CG 4.41Å
223	G	79.3	Confident	85.7	Confident	17 Å²	17	47.2 Å²	47.2	18%	0.175	24%	0.239	C	C	.	.			trans	44.8	-155.6	-173.3	0	0	0	0	0	114.2	N219 I221 R299	N219-G223 WeakPolarHBondContact O-CA 3.46Å; N219-G223 PolarHBondContact O-N 3.46Å; I221-G223 VanDerWaalsContact C-N 3.32Å; I221-G223 PolarHBondContact O-N 3.07Å; G223-R299 VanDerWaalsContact CA-NH2 3.27Å; G223-R299 VanDerWaalsContact N-NH2 3.17Å
224	T	78.9	Confident	85.5	Confident	77 Å²	77	47.4 Å²	47.4	47%	0.472	24%	0.24	S	C	.	.	B	Isolated β-bridge	trans	-87.6	159.7	-177.8	54.2	0	0	0	0	112.1
225	R	78.1	Confident	85.4	Confident	88 Å²	88	49.5 Å²	49.5	33%	0.332	25%	0.253	S	S	.	.	P	Polyproline II helix	trans	-59.6	164.9	164.4	-71.5	177.5	68.9	144.7	-0.8	110.5	E230 E233 K514 K515 V517	R225-E230 HydrophobicContact CB-CG 3.9Å; R225-E230 VanDerWaalsContact CB-OE1 3.24Å; R225-E230 WeakPolarHBondContact CB-OE1 3.47Å; R225-E230 WeakPolarHBondContact CD-OE1 3.08Å; R225-E230 IonicContact NE-OE1 2.68Å; R225-E233 IonicContact CZ-OE2 3.49Å; R225-E233 IonicContact NH2-OE1 2.84Å; R225-E233 PolarHBondContact NH2-OE1 2.93Å; R225-E233 IonicContact NH2-OE2 3.78Å; R225-E233 PolarHBondContact NH2-OE2 3.3Å; R225-K514 HydrophobicContact CG-CB 3.88Å; R225-K515 PolarHBondContact N-O 3.35Å; R225-K515 VanDerWaalsContact N-O 3.09Å; R225-V517 HydrophobicContact CB-CG2 4.48Å; R225-V517 WeakPolarHBondContact O-CG2 3.45Å
226	N	78.3	Confident	85.5	Confident	110 Å²	110	56 Å²	56	59%	0.588	28%	0.283	S	S	*	.	P	Polyproline II helix	trans	-80.9	129.3	176.9	-175.9	10.9	0	0	0	109.4	A228 Y229 E230	N226-A228 VanDerWaalsContact C-N 3.32Å; N226-A228 PolarHBondContact O-N 3.38Å; N226-A228 PolarHBondContact OD1-N 3.35Å; N226-Y229 PolarHBondContact O-N 3.19Å; N226-Y229 VanDerWaalsContact O-N 3.15Å; N226-E230 PolarHBondContact O-N 3.37Å
227	A	79.1	Confident	85.5	Confident	12 Å²	12	57.2 Å²	57.2	10%	0.099	29%	0.29	C	S	.	.	H	α-helix	trans	-59.9	-41.6	-178.7	0	0	0	0	0	111.9	Y229 E230 R231 I286 V517	A227-Y229 VanDerWaalsContact C-N 3.3Å; A227-Y229 PolarHBondContact O-N 3.14Å; A227-E230 PolarHBondContact O-N 3.35Å; A227-R231 WeakPolarHBondContact O-CB 3.46Å; A227-R231 PolarHBondContact O-N 2.83Å; A227-I286 HydrophobicContact CB-CG2 4.13Å; A227-V517 HydrophobicContact CB-CG1 4.28Å; A227-V517 HydrophobicContact CB-CG2 4.35Å
228	A	81.3	Confident	85.6	Confident	36 Å²	36	58 Å²	58	30%	0.298	29%	0.294	S	S	.	.	H	α-helix	trans	-63.4	-35.6	177.8	0	0	0	0	0	112.7	N226 L232 E287	N226-A228 VanDerWaalsContact C-N 3.32Å; N226-A228 PolarHBondContact O-N 3.38Å; N226-A228 PolarHBondContact OD1-N 3.35Å; A228-L232 PolarHBondContact O-N 3.44Å; A228-L232 VanDerWaalsContact O-N 3.08Å; A228-E287 WeakPolarHBondContact CB-OE1 3.14Å
229	Y	84.1	Confident	85.9	Confident	139 Å²	139	62.1 Å²	62.1	55%	0.545	31%	0.313	S	S	.	.	H	α-helix	trans	-74.9	-41.9	177.9	-172.6	-95.4	0	0	0	111.8	N226 A227 R231 L232 E233	N226-Y229 PolarHBondContact O-N 3.19Å; N226-Y229 VanDerWaalsContact O-N 3.15Å; A227-Y229 VanDerWaalsContact C-N 3.3Å; A227-Y229 PolarHBondContact O-N 3.14Å; Y229-R231 PolarHBondContact O-N 3.34Å; Y229-L232 PolarHBondContact O-N 3.01Å; Y229-E233 PolarHBondContact O-N 2.83Å
230	E	83.4	Confident	86.3	Confident	8 Å²	8	64.9 Å²	64.9	4%	0.037	32%	0.324	C	S	.	.	H	α-helix	trans	-63.3	-32.4	173	-69.7	-164.4	158	0	0	112.2	R225 N226 A227 N234 L283 S516 V517	R225-E230 HydrophobicContact CB-CG 3.9Å; R225-E230 VanDerWaalsContact CB-OE1 3.24Å; R225-E230 WeakPolarHBondContact CB-OE1 3.47Å; R225-E230 WeakPolarHBondContact CD-OE1 3.08Å; R225-E230 IonicContact NE-OE1 2.68Å; N226-E230 PolarHBondContact O-N 3.37Å; A227-E230 PolarHBondContact O-N 3.35Å; E230-N234 VanDerWaalsContact O-CB 3.25Å; E230-N234 WeakPolarHBondContact O-CB 3.33Å; E230-N234 PolarHBondContact O-N 3.45Å; E230-L283 HydrophobicContact CB-CD1 4.38Å; E230-L283 HydrophobicContact CB-CD2 4.02Å; E230-S516 WeakPolarHBondContact OE1-CA 3.32Å; E230-S516 WeakPolarHBondContact OE1-CB 3.17Å; E230-S516 PolarHBondContact OE1-OG 2.9Å; E230-S516 PolarHBondContact OE2-OG 3.01Å; E230-V517 PolarHBondContact OE1-N 2.84Å; E230-V517 WeakPolarHBondContact OE2-CB 3.28Å; E230-V517 PolarHBondContact OE2-N 3.07Å
231	R	84.6	Confident	86.6	Confident	56 Å²	56	62.9 Å²	62.9	21%	0.211	31%	0.314	C	S	.	.	H	α-helix	trans	-66.2	-46.5	174.1	-167.6	-176.9	177.7	-175.4	0.8	111.1	A227 Y229 E233 N234 T235 D280 L283 E284 E287	A227-R231 WeakPolarHBondContact O-CB 3.46Å; A227-R231 PolarHBondContact O-N 2.83Å; Y229-R231 PolarHBondContact O-N 3.34Å; R231-E233 VanDerWaalsContact C-N 3.35Å; R231-E233 PolarHBondContact O-N 3.24Å; R231-N234 PolarHBondContact O-N 3.13Å; R231-T235 PolarHBondContact O-N 3.15Å; R231-T235 PolarHBondContact O-OG1 2.91Å; R231-D280 WeakPolarHBondContact CG-OD1 3.41Å; R231-D280 IonicContact NE-OD1 2.82Å; R231-L283 HydrophobicContact CB-CB 4.09Å; R231-L283 HydrophobicContact CB-CD1 4.11Å; R231-L283 HydrophobicContact CG-CB 4.15Å; R231-L283 HydrophobicContact CG-CD1 4.49Å; R231-E284 IonicContact CZ-OE1 2.62Å; R231-E284 IonicContact NH1-OE1 3.28Å; R231-E284 IonicContact NH2-OE1 3.51Å; R231-E284 PolarHBondContact NH2-OE1 3.34Å; R231-E284 IonicContact NH2-OE2 3.99Å; R231-E287 WeakPolarHBondContact CD-OE2 3.45Å; R231-E287 IonicContact CZ-OE2 3.57Å; R231-E287 IonicContact NE-OE2 3.6Å; R231-E287 IonicContact NH1-OE2 3.23Å; R231-E287 PolarHBondContact NH1-OE2 2.95Å
232	L	89.5	Confident	86.9	Confident	114 Å²	114	63.5 Å²	63.5	60%	0.597	32%	0.316	S	S	*	.	H	α-helix	trans	-57.7	-46.9	177.1	-171.9	70.5	0	0	0	112	A228 Y229 T235 E236	A228-L232 PolarHBondContact O-N 3.44Å; A228-L232 VanDerWaalsContact O-N 3.08Å; Y229-L232 PolarHBondContact O-N 3.01Å; L232-T235 PolarHBondContact O-N 3Å; L232-E236 PolarHBondContact O-N 3.44Å
233	E	88	Confident	87.4	Confident	78 Å²	78	67 Å²	67	36%	0.364	33%	0.333	S	S	.	.	H	α-helix	trans	-61.3	-42.3	175.8	-174.4	177.4	-163.1	0	0	111.6	R225 Y229 R231 T235 E236 D237	R225-E233 IonicContact CZ-OE2 3.49Å; R225-E233 IonicContact NH2-OE1 2.84Å; R225-E233 PolarHBondContact NH2-OE1 2.93Å; R225-E233 IonicContact NH2-OE2 3.78Å; R225-E233 PolarHBondContact NH2-OE2 3.3Å; Y229-E233 PolarHBondContact O-N 2.83Å; R231-E233 VanDerWaalsContact C-N 3.35Å; R231-E233 PolarHBondContact O-N 3.24Å; E233-T235 VanDerWaalsContact C-N 3.35Å; E233-T235 PolarHBondContact O-N 2.92Å; E233-E236 PolarHBondContact O-N 3.26Å; E233-D237 PolarHBondContact O-N 3.43Å
234	N	89.5	Confident	88	Confident	4 Å²	4	71.5 Å²	71.5	2%	0.021	35%	0.349	C	S	.	.	H	α-helix	trans	-68.2	-32.4	177.2	-170.1	75.3	0	0	0	112.6	E230 R231 I238 L276 D280 L283	E230-N234 VanDerWaalsContact O-CB 3.25Å; E230-N234 WeakPolarHBondContact O-CB 3.33Å; E230-N234 PolarHBondContact O-N 3.45Å; R231-N234 PolarHBondContact O-N 3.13Å; N234-I238 VanDerWaalsContact O-CG1 3.26Å; N234-I238 WeakPolarHBondContact O-CG1 3.4Å; N234-I238 PolarHBondContact O-N 3.35Å; N234-L276 PolarHBondContact ND2-O 2.88Å; N234-L276 VanDerWaalsContact OD1-CD2 3.26Å; N234-L276 WeakPolarHBondContact OD1-CD2 3.29Å; N234-D280 WeakPolarHBondContact ND2-CB 3.47Å; N234-D280 PolarHBondContact ND2-N 3.41Å; N234-L283 HydrophobicContact CB-CD1 4.04Å
235	T	91.6	Very high	88.7	Confident	48 Å²	48	68.4 Å²	68.4	29%	0.294	33%	0.329	S	S	.	.	H	α-helix	trans	-67.4	-41.8	173.1	-58.1	0	0	0	0	111.3	R231 L232 E233 I238 E239	R231-T235 PolarHBondContact O-N 3.15Å; R231-T235 PolarHBondContact O-OG1 2.91Å; L232-T235 PolarHBondContact O-N 3Å; E233-T235 VanDerWaalsContact C-N 3.35Å; E233-T235 PolarHBondContact O-N 2.92Å; T235-I238 WeakPolarHBondContact O-CB 3.41Å; T235-I238 PolarHBondContact O-N 2.88Å; T235-E239 WeakPolarHBondContact O-CG 3.39Å; T235-E239 PolarHBondContact O-N 3.4Å
236	E	93	Very high	89.3	Confident	135 Å²	135	70.4 Å²	70.4	63%	0.631	34%	0.343	S	S	*	.	H	α-helix	trans	-60.5	-44.7	174.6	-171.7	175.2	-175.1	0	0	111.4	L232 E233 I238 E239 E240	L232-E236 PolarHBondContact O-N 3.44Å; E233-E236 PolarHBondContact O-N 3.26Å; E236-I238 VanDerWaalsContact C-N 3.32Å; E236-I238 PolarHBondContact O-N 2.91Å; E236-E239 PolarHBondContact O-N 3.08Å; E236-E240 PolarHBondContact O-N 3.43Å
237	D	91.1	Very high	89.9	Confident	52 Å²	52	67.5 Å²	67.5	28%	0.278	33%	0.334	S	S	.	.	H	α-helix	trans	-60.4	-38.8	173.9	-82.4	-8	0	0	0	112.5	E233 V241 L276	E233-D237 PolarHBondContact O-N 3.43Å; D237-V241 VanDerWaalsContact O-CG2 3.29Å; D237-V241 WeakPolarHBondContact O-CG2 3.35Å; D237-V241 PolarHBondContact O-N 3.45Å; D237-V241 VanDerWaalsContact O-N 3.09Å; D237-L276 HydrophobicContact CB-CD1 4.06Å; D237-L276 HydrophobicContact CB-CD2 4.18Å
238	I	93.1	Very high	90.4	Very high	19 Å²	19	67.7 Å²	67.7	10%	0.097	33%	0.333	C	S	.	.	H	α-helix	trans	-62.8	-47	175.7	-74.1	167	0	0	0	109.9	N234 T235 E236 V241 E242 L273 L276 R277 D280	N234-I238 VanDerWaalsContact O-CG1 3.26Å; N234-I238 WeakPolarHBondContact O-CG1 3.4Å; N234-I238 PolarHBondContact O-N 3.35Å; T235-I238 WeakPolarHBondContact O-CB 3.41Å; T235-I238 PolarHBondContact O-N 2.88Å; E236-I238 VanDerWaalsContact C-N 3.32Å; E236-I238 PolarHBondContact O-N 2.91Å; I238-V241 PolarHBondContact O-N 3.01Å; I238-E242 HydrophobicContact CG2-CG 4.39Å; I238-E242 WeakPolarHBondContact O-CB 3.36Å; I238-E242 WeakPolarHBondContact O-CG 3.29Å; I238-E242 PolarHBondContact O-N 3.03Å; I238-L273 HydrophobicContact CG2-CD1 3.99Å; I238-L276 HydrophobicContact CD1-CB 4.23Å; I238-L276 HydrophobicContact CG1-CB 3.64Å; I238-L276 HydrophobicContact CG1-CD1 4.3Å; I238-R277 HydrophobicContact CD1-CG 4.27Å; I238-D280 HydrophobicContact CD1-CB 4.16Å
239	E	94.8	Very high	90.8	Very high	110 Å²	110	72.6 Å²	72.6	51%	0.514	34%	0.344	S	S	.	.	H	α-helix	trans	-61.6	-43.6	179.3	-71.3	-179.8	-169.7	0	0	111.8	T235 E236 V241 E242 Q243	T235-E239 WeakPolarHBondContact O-CG 3.39Å; T235-E239 PolarHBondContact O-N 3.4Å; E236-E239 PolarHBondContact O-N 3.08Å; E239-V241 PolarHBondContact O-N 2.91Å; E239-E242 PolarHBondContact O-N 3.34Å; E239-Q243 WeakPolarHBondContact O-CB 3.48Å; E239-Q243 VanDerWaalsContact O-CG 3.27Å; E239-Q243 WeakPolarHBondContact O-CG 3.42Å; E239-Q243 PolarHBondContact O-N 3.48Å
240	E	94.6	Very high	91	Very high	107 Å²	107	69 Å²	69	50%	0.5	34%	0.339	S	S	.	.	H	α-helix	trans	-61.2	-46.1	177.2	-170.2	-173.3	-176.3	0	0	111.6	E236 Q243 H244	E236-E240 PolarHBondContact O-N 3.43Å; E240-Q243 PolarHBondContact O-N 3.16Å; E240-H244 PolarHBondContact O-N 2.92Å
241	V	93.6	Very high	91.1	Very high	11 Å²	11	74.8 Å²	74.8	7%	0.067	36%	0.364	C	S	.	.	H	α-helix	trans	-66.1	-40.2	178.8	174.1	0	0	0	0	111.2	D237 I238 E239 H244 I245 C269 L273 L276	D237-V241 VanDerWaalsContact O-CG2 3.29Å; D237-V241 WeakPolarHBondContact O-CG2 3.35Å; D237-V241 PolarHBondContact O-N 3.45Å; D237-V241 VanDerWaalsContact O-N 3.09Å; I238-V241 PolarHBondContact O-N 3.01Å; E239-V241 PolarHBondContact O-N 2.91Å; V241-H244 PolarHBondContact O-N 3.34Å; V241-I245 HydrophobicContact CG1-CD1 4.04Å; V241-I245 WeakPolarHBondContact O-CG1 3.26Å; V241-I245 PolarHBondContact O-N 3.27Å; V241-C269 HydrophobicContact CG1-CB 4.16Å; V241-C269 WeakPolarHBondContact CG1-O 3.42Å; V241-L273 HydrophobicContact CG1-CB 4.1Å; V241-L273 HydrophobicContact CG1-CD1 4.27Å; V241-L276 HydrophobicContact CG2-CD1 4.05Å
242	E	94.6	Very high	90.8	Very high	64 Å²	64	74.1 Å²	74.1	30%	0.299	37%	0.368	S	S	.	.	H	α-helix	trans	-63.2	-42	175.6	-76.3	-170.3	177.1	0	0	112	I238 E239 H244 I245 Q246 L273 R277	I238-E242 HydrophobicContact CG2-CG 4.39Å; I238-E242 WeakPolarHBondContact O-CB 3.36Å; I238-E242 WeakPolarHBondContact O-CG 3.29Å; I238-E242 PolarHBondContact O-N 3.03Å; E239-E242 PolarHBondContact O-N 3.34Å; E242-H244 VanDerWaalsContact C-N 3.34Å; E242-H244 PolarHBondContact O-N 3.48Å; E242-I245 PolarHBondContact O-N 2.9Å; E242-Q246 WeakPolarHBondContact O-CG 3.34Å; E242-Q246 PolarHBondContact O-N 3.49Å; E242-L273 HydrophobicContact CG-CD1 3.69Å; E242-L273 HydrophobicContact CG-CD2 4.36Å; E242-R277 IonicContact OE1-CZ 2.87Å; E242-R277 IonicContact OE1-NE 3.69Å; E242-R277 IonicContact OE1-NH2 3.96Å; E242-R277 PolarHBondContact OE1-NH2 2.85Å
243	Q	94.4	Very high	90.1	Very high	122 Å²	122	77.3 Å²	77.3	57%	0.57	38%	0.377	S	S	*	.	H	α-helix	trans	-60.9	-42.6	173.9	-72.5	176	15.9	0	0	111.6	E239 E240 Q246 A247	E239-Q243 WeakPolarHBondContact O-CB 3.48Å; E239-Q243 VanDerWaalsContact O-CG 3.27Å; E239-Q243 WeakPolarHBondContact O-CG 3.42Å; E239-Q243 PolarHBondContact O-N 3.48Å; E240-Q243 PolarHBondContact O-N 3.16Å; Q243-Q246 PolarHBondContact O-N 2.85Å; Q243-A247 WeakPolarHBondContact O-CB 3.44Å; Q243-A247 PolarHBondContact O-N 3.26Å
244	H	92.6	Very high	89.6	Confident	112 Å²	112	80 Å²	80	52%	0.519	39%	0.394	S	S	.	.	H	α-helix	trans	-62.1	-41.9	174.4	-98	30.8	0	0	0	112.8	E240 V241 E242 Q246 A247 I248	E240-H244 PolarHBondContact O-N 2.92Å; V241-H244 PolarHBondContact O-N 3.34Å; E242-H244 VanDerWaalsContact C-N 3.34Å; E242-H244 PolarHBondContact O-N 3.48Å; H244-Q246 VanDerWaalsContact C-N 3.35Å; H244-A247 PolarHBondContact O-N 3.44Å; H244-I248 WeakPolarHBondContact O-CG1 3.46Å; H244-I248 PolarHBondContact O-N 2.88Å
245	I	92.6	Very high	88.8	Confident	11 Å²	11	83.3 Å²	83.3	6%	0.056	43%	0.428	C	S	.	.	H	α-helix	trans	-62.2	-44.7	175.1	-69.5	167.5	0	0	0	110.3	V241 E242 A247 I248 R249 C269 E270 L273	V241-I245 HydrophobicContact CG1-CD1 4.04Å; V241-I245 WeakPolarHBondContact O-CG1 3.26Å; V241-I245 PolarHBondContact O-N 3.27Å; E242-I245 PolarHBondContact O-N 2.9Å; I245-A247 PolarHBondContact O-N 3.27Å; I245-I248 PolarHBondContact O-N 3.45Å; I245-R249 HydrophobicContact CG2-CG 4.35Å; I245-R249 WeakPolarHBondContact O-CB 3.22Å; I245-R249 WeakPolarHBondContact O-CG 3.4Å; I245-R249 PolarHBondContact O-N 3.09Å; I245-C269 HydrophobicContact CD1-CB 4.08Å; I245-C269 HydrophobicContact CG1-CB 3.67Å; I245-E270 HydrophobicContact CD1-CG 4.21Å; I245-L273 HydrophobicContact CD1-CB 4.47Å; I245-L273 HydrophobicContact CD1-CD2 4.06Å
246	Q	91.9	Very high	88.1	Confident	131 Å²	131	90.1 Å²	90.1	61%	0.612	45%	0.449	S	S	*	.	H	α-helix	trans	-63.2	-40.6	177.4	-70.8	178.7	16.2	0	0	112	E242 Q243 H244 I248 R249 S250	E242-Q246 WeakPolarHBondContact O-CG 3.34Å; E242-Q246 PolarHBondContact O-N 3.49Å; Q243-Q246 PolarHBondContact O-N 2.85Å; H244-Q246 VanDerWaalsContact C-N 3.35Å; Q246-I248 PolarHBondContact O-N 3.24Å; Q246-R249 PolarHBondContact O-N 3.38Å; Q246-S250 WeakPolarHBondContact O-CB 3.06Å; Q246-S250 PolarHBondContact O-N 2.97Å; Q246-S250 PolarHBondContact O-OG 3.13Å
247	A	91.4	Very high	87.4	Confident	48 Å²	48	89.7 Å²	89.7	40%	0.397	46%	0.458	S	S	.	.	H	α-helix	trans	-66.4	-33.2	176.8	0	0	0	0	0	113.1	Q243 H244 I245 S250	Q243-A247 WeakPolarHBondContact O-CB 3.44Å; Q243-A247 PolarHBondContact O-N 3.26Å; H244-A247 PolarHBondContact O-N 3.44Å; I245-A247 PolarHBondContact O-N 3.27Å; A247-S250 PolarHBondContact O-OG 3.38Å
248	I	89.6	Confident	86.9	Confident	17 Å²	17	89.8 Å²	89.8	9%	0.087	46%	0.458	C	S	.	.	H	α-helix	trans	-75	-43.1	173.2	-65	166.1	0	0	0	110.3	H244 I245 Q246 S250 K251 L258 D262 L266	H244-I248 WeakPolarHBondContact O-CG1 3.46Å; H244-I248 PolarHBondContact O-N 2.88Å; I245-I248 PolarHBondContact O-N 3.45Å; Q246-I248 PolarHBondContact O-N 3.24Å; I248-S250 VanDerWaalsContact C-N 3.29Å; I248-S250 PolarHBondContact O-N 2.95Å; I248-K251 WeakPolarHBondContact O-CB 3.46Å; I248-K251 PolarHBondContact O-N 3.3Å; I248-L258 HydrophobicContact CG2-CD2 3.72Å; I248-D262 HydrophobicContact CG2-CB 4.17Å; I248-L266 HydrophobicContact CB-CD1 4.37Å; I248-L266 HydrophobicContact CG2-CB 4.27Å; I248-L266 HydrophobicContact CG2-CD1 3.88Å
249	R	88.2	Confident	86.6	Confident	139 Å²	139	92.2 Å²	92.2	53%	0.525	48%	0.477	S	S	.	.	H	α-helix	trans	-63.7	-33.8	177.9	-75.1	-177.4	-178.1	-176	2.4	112.2	I245 Q246 K251 S252 K253 L266 E270	I245-R249 HydrophobicContact CG2-CG 4.35Å; I245-R249 WeakPolarHBondContact O-CB 3.22Å; I245-R249 WeakPolarHBondContact O-CG 3.4Å; I245-R249 PolarHBondContact O-N 3.09Å; Q246-R249 PolarHBondContact O-N 3.38Å; R249-K251 VanDerWaalsContact C-N 3.33Å; R249-K251 PolarHBondContact O-N 3.15Å; R249-S252 WeakPolarHBondContact O-CB 3.09Å; R249-S252 PolarHBondContact O-N 2.71Å; R249-K253 PolarHBondContact O-N 3.42Å; R249-L266 HydrophobicContact CG-CD1 3.87Å; R249-E270 IonicContact CZ-OE1 2.83Å; R249-E270 IonicContact NH2-OE1 3.78Å; R249-E270 PolarHBondContact NH2-OE1 2.84Å
250	S	88.9	Confident	86.1	Confident	63 Å²	63	90.4 Å²	90.4	44%	0.441	48%	0.48	S	S	.	.	H	α-helix	trans	-65	-34.3	176.7	68.6	0	0	0	0	112.5	Q246 A247 I248 S252 K253	Q246-S250 WeakPolarHBondContact O-CB 3.06Å; Q246-S250 PolarHBondContact O-N 2.97Å; Q246-S250 PolarHBondContact O-OG 3.13Å; A247-S250 PolarHBondContact O-OG 3.38Å; I248-S250 VanDerWaalsContact C-N 3.29Å; I248-S250 PolarHBondContact O-N 2.95Å; S250-S252 PolarHBondContact O-N 2.93Å; S250-S252 VanDerWaalsContact O-N 3.15Å; S250-K253 WeakPolarHBondContact O-CB 3.42Å; S250-K253 PolarHBondContact O-N 3.43Å
251	K	85.9	Confident	85.8	Confident	130 Å²	130	94.7 Å²	94.7	57%	0.565	49%	0.492	S	S	*	.	T	Hydrogen-bonded Turn	trans	-61.5	-20.3	171.8	-63.5	175	-176.9	-179.5	0	113.5	I248 R249	I248-K251 WeakPolarHBondContact O-CB 3.46Å; I248-K251 PolarHBondContact O-N 3.3Å; R249-K251 VanDerWaalsContact C-N 3.33Å; R249-K251 PolarHBondContact O-N 3.15Å
252	S	77.4	Confident	85.6	Confident	41 Å²	41	96 Å²	96	29%	0.287	50%	0.499	S	S	.	.	T	Hydrogen-bonded Turn	trans	-94.4	-6.3	178.1	-164.7	0	0	0	0	113.6	R249 S250 D254 G255	R249-S252 WeakPolarHBondContact O-CB 3.09Å; R249-S252 PolarHBondContact O-N 2.71Å; S250-S252 PolarHBondContact O-N 2.93Å; S250-S252 VanDerWaalsContact O-N 3.15Å; S252-D254 PolarHBondContact O-N 2.75Å; S252-G255 PolarHBondContact O-N 3.16Å
253	K	76.2	Confident	85.3	Confident	182 Å²	182	100.9 Å²	100.9	79%	0.791	51%	0.514	S	S	*	.	T	Hydrogen-bonded Turn	trans	-65.3	-24.1	-176.2	-92.3	-173.6	169	-176.9	0	113.5	R249 S250 G255	R249-K253 PolarHBondContact O-N 3.42Å; S250-K253 WeakPolarHBondContact O-CB 3.42Å; S250-K253 PolarHBondContact O-N 3.43Å; K253-G255 PolarHBondContact O-N 3.32Å; K253-G255 VanDerWaalsContact O-N 3.09Å
254	D	76.5	Confident	85.1	Confident	135 Å²	135	103.9 Å²	103.9	72%	0.722	52%	0.52	S	S	*	.	T	Hydrogen-bonded Turn	trans	-76.5	12.1	-180	-59.4	-27.2	0	0	0	113.7	S252 R256	S252-D254 PolarHBondContact O-N 2.75Å; D254-R256 PolarHBondContact O-N 3.45Å
255	G	71.9	Confident	85	Confident	72 Å²	72	100.6 Å²	100.6	74%	0.742	51%	0.508	S	S	*	.	S	Bend	trans	75.3	-0.6	-179.3	0	0	0	0	0	114.8	S252 K253	S252-G255 PolarHBondContact O-N 3.16Å; K253-G255 PolarHBondContact O-N 3.32Å; K253-G255 VanDerWaalsContact O-N 3.09Å
256	R	77.3	Confident	85	Confident	192 Å²	192	101.1 Å²	101.1	73%	0.725	51%	0.511	S	S	*	.	P	Polyproline II helix	trans	-78.4	137.5	176.4	-63.6	-175.8	-174.7	-160.3	1.4	110.7	D254 L258	D254-R256 PolarHBondContact O-N 3.45Å; R256-L258 PolarHBondContact O-N 2.98Å
257	P	77.8	Confident	84.9	Confident	126 Å²	126	100.6 Å²	100.6	82%	0.818	51%	0.507	S	S	*	.	P	Polyproline II helix	trans	-63.5	134.9	175.6	25.8	-32.4	0	0	0	110.4
258	L	82.4	Confident	85	Confident	54 Å²	54	104.4 Å²	104.4	28%	0.283	52%	0.516	S	S	.	.	P	Polyproline II helix	trans	-54.4	137.8	173.4	-80.9	149.8	0	0	0	110.8	I248 R256 D262	I248-L258 HydrophobicContact CG2-CD2 3.72Å; R256-L258 PolarHBondContact O-N 2.98Å; L258-D262 HydrophobicContact CD2-CB 3.84Å
259	S	85.3	Confident	85.1	Confident	70 Å²	70	104.8 Å²	104.8	49%	0.49	52%	0.52	S	S	.	.	P	Polyproline II helix	trans	-55.4	146	171.6	177.9	0	0	0	0	110.5	R261 D262 R263	S259-R261 PolarHBondContact O-N 2.77Å; S259-R261 VanDerWaalsContact O-N 3.09Å; S259-D262 PolarHBondContact O-N 3.47Å; S259-R263 PolarHBondContact O-N 3.45Å
260	A	85.9	Confident	85.3	Confident	71 Å²	71	100.6 Å²	100.6	59%	0.587	51%	0.507	S	S	*	.	H	α-helix	trans	-55.9	-30	178.3	0	0	0	0	0	112.6	R264	A260-R264 WeakPolarHBondContact O-CG 3.23Å; A260-R264 PolarHBondContact O-N 3.34Å
261	R	88	Confident	85.5	Confident	197 Å²	197	103 Å²	103	74%	0.743	51%	0.511	S	S	*	.	H	α-helix	trans	-68.8	-50.4	173.1	-174.8	174.8	-177.8	161.3	-0.1	111.6	S259 R263 R264 T265	S259-R261 PolarHBondContact O-N 2.77Å; S259-R261 VanDerWaalsContact O-N 3.09Å; R261-R263 PolarHBondContact O-N 3.27Å; R261-R264 WeakPolarHBondContact O-CB 3.26Å; R261-R264 PolarHBondContact O-N 2.87Å; R261-R264 VanDerWaalsContact O-N 3.07Å; R261-T265 PolarHBondContact O-N 3.24Å; R261-T265 PolarHBondContact O-OG1 2.92Å
262	D	88.3	Confident	85.7	Confident	40 Å²	40	103 Å²	103	21%	0.214	51%	0.507	C	S	.	.	H	α-helix	trans	-63.3	-32.8	-179.6	-67.6	-18.2	0	0	0	112	I248 L258 S259 T265 L266	I248-D262 HydrophobicContact CG2-CB 4.17Å; L258-D262 HydrophobicContact CD2-CB 3.84Å; S259-D262 PolarHBondContact O-N 3.47Å; D262-T265 VanDerWaalsContact CA-OG1 3.28Å; D262-T265 WeakPolarHBondContact CA-OG1 3.38Å; D262-T265 PolarHBondContact O-OG1 3.5Å; D262-L266 VanDerWaalsContact O-CB 3.22Å; D262-L266 WeakPolarHBondContact O-CB 3.33Å; D262-L266 PolarHBondContact O-N 2.93Å
263	R	88.3	Confident	86.4	Confident	165 Å²	165	102 Å²	102	62%	0.623	50%	0.498	S	S	*	.	H	α-helix	trans	-67.6	-36.5	174.1	-165.3	175.6	-174.5	176.7	1.2	112.6	S259 R261 K267	S259-R263 PolarHBondContact O-N 3.45Å; R261-R263 PolarHBondContact O-N 3.27Å; R263-K267 WeakPolarHBondContact O-CG 3.25Å; R263-K267 PolarHBondContact O-N 3.44Å
264	R	90.8	Very high	87.1	Confident	185 Å²	185	101 Å²	101	70%	0.698	49%	0.49	S	S	*	.	H	α-helix	trans	-70.8	-44.4	175	-72.1	176.6	-172.2	175.7	2.3	111.2	A260 R261 L266 K267 Q268	A260-R264 WeakPolarHBondContact O-CG 3.23Å; A260-R264 PolarHBondContact O-N 3.34Å; R261-R264 WeakPolarHBondContact O-CB 3.26Å; R261-R264 PolarHBondContact O-N 2.87Å; R261-R264 VanDerWaalsContact O-N 3.07Å; R264-L266 VanDerWaalsContact C-N 3.33Å; R264-L266 PolarHBondContact O-N 3.37Å; R264-K267 PolarHBondContact O-N 2.81Å; R264-Q268 WeakPolarHBondContact O-CG 3.49Å; R264-Q268 PolarHBondContact O-N 2.88Å
265	T	90.5	Very high	87.6	Confident	43 Å²	43	98.7 Å²	98.7	26%	0.264	48%	0.481	S	S	.	.	H	α-helix	trans	-64.4	-39	177.5	54.1	0	0	0	0	111.4	R261 D262 K267 Q268 C269	R261-T265 PolarHBondContact O-N 3.24Å; R261-T265 PolarHBondContact O-OG1 2.92Å; D262-T265 VanDerWaalsContact CA-OG1 3.28Å; D262-T265 WeakPolarHBondContact CA-OG1 3.38Å; D262-T265 PolarHBondContact O-OG1 3.5Å; T265-K267 PolarHBondContact O-N 3.02Å; T265-Q268 PolarHBondContact O-N 2.9Å; T265-C269 WeakPolarHBondContact O-CB 3.48Å; T265-C269 PolarHBondContact O-N 3.43Å; T265-C269 PolarHBondContact O-SG 3.43Å
266	L	91.9	Very high	88.4	Confident	22 Å²	22	95.9 Å²	95.9	12%	0.115	45%	0.449	C	S	.	.	H	α-helix	trans	-61.3	-44.1	175.1	-176.2	133.6	0	0	0	111.9	I248 R249 D262 R264 C269 E270	I248-L266 HydrophobicContact CB-CD1 4.37Å; I248-L266 HydrophobicContact CG2-CB 4.27Å; I248-L266 HydrophobicContact CG2-CD1 3.88Å; R249-L266 HydrophobicContact CG-CD1 3.87Å; D262-L266 VanDerWaalsContact O-CB 3.22Å; D262-L266 WeakPolarHBondContact O-CB 3.33Å; D262-L266 PolarHBondContact O-N 2.93Å; R264-L266 VanDerWaalsContact C-N 3.33Å; R264-L266 PolarHBondContact O-N 3.37Å; L266-C269 PolarHBondContact O-N 3.14Å; L266-E270 HydrophobicContact CD2-CG 4.46Å; L266-E270 WeakPolarHBondContact CD2-OE1 3.43Å; L266-E270 WeakPolarHBondContact O-CB 3.01Å; L266-E270 WeakPolarHBondContact O-CG 3.3Å; L266-E270 PolarHBondContact O-N 3.1Å
267	K	91.5	Very high	89	Confident	120 Å²	120	92.6 Å²	92.6	52%	0.522	44%	0.436	S	S	.	.	H	α-helix	trans	-60.5	-45	173.9	-76.4	-174.3	175.1	-166.8	0	112.3	R263 R264 T265 C269 E270 E271	R263-K267 WeakPolarHBondContact O-CG 3.25Å; R263-K267 PolarHBondContact O-N 3.44Å; R264-K267 PolarHBondContact O-N 2.81Å; T265-K267 PolarHBondContact O-N 3.02Å; K267-C269 VanDerWaalsContact C-N 3.35Å; K267-C269 PolarHBondContact O-N 3.12Å; K267-E270 PolarHBondContact O-N 2.84Å; K267-E271 WeakPolarHBondContact O-CG 3.08Å; K267-E271 PolarHBondContact O-N 3.2Å
268	Q	92.5	Very high	89.5	Confident	128 Å²	128	90.8 Å²	90.8	60%	0.598	42%	0.415	S	S	*	.	H	α-helix	trans	-62.1	-41.1	176.8	-73.2	176.9	-22.2	0	0	112.2	R264 T265 E271 R272	R264-Q268 WeakPolarHBondContact O-CG 3.49Å; R264-Q268 PolarHBondContact O-N 2.88Å; T265-Q268 PolarHBondContact O-N 2.9Å; Q268-E271 PolarHBondContact O-N 3.32Å; Q268-R272 WeakPolarHBondContact O-CB 3.48Å; Q268-R272 PolarHBondContact O-N 2.86Å
269	C	91.6	Very high	89.6	Confident	25 Å²	25	91.7 Å²	91.7	17%	0.169	42%	0.415	C	S	.	.	H	α-helix	trans	-64.8	-41.8	174.5	-70.3	0	0	0	0	111.7	V241 I245 T265 L266 K267 R272 L273	V241-C269 HydrophobicContact CG1-CB 4.16Å; V241-C269 WeakPolarHBondContact CG1-O 3.42Å; I245-C269 HydrophobicContact CD1-CB 4.08Å; I245-C269 HydrophobicContact CG1-CB 3.67Å; T265-C269 WeakPolarHBondContact O-CB 3.48Å; T265-C269 PolarHBondContact O-N 3.43Å; T265-C269 PolarHBondContact O-SG 3.43Å; L266-C269 PolarHBondContact O-N 3.14Å; K267-C269 VanDerWaalsContact C-N 3.35Å; K267-C269 PolarHBondContact O-N 3.12Å; C269-R272 PolarHBondContact O-N 3.37Å; C269-L273 WeakPolarHBondContact O-CB 3.19Å; C269-L273 PolarHBondContact O-N 3.32Å
270	E	93.1	Very high	89.6	Confident	52 Å²	52	89.9 Å²	89.9	24%	0.243	40%	0.4	C	S	.	.	H	α-helix	trans	-65.7	-39.6	176.6	-74.7	-179.8	170.1	0	0	112.1	I245 R249 L266 K267 L273 R274	I245-E270 HydrophobicContact CD1-CG 4.21Å; R249-E270 IonicContact CZ-OE1 2.83Å; R249-E270 IonicContact NH2-OE1 3.78Å; R249-E270 PolarHBondContact NH2-OE1 2.84Å; L266-E270 HydrophobicContact CD2-CG 4.46Å; L266-E270 WeakPolarHBondContact CD2-OE1 3.43Å; L266-E270 WeakPolarHBondContact O-CB 3.01Å; L266-E270 WeakPolarHBondContact O-CG 3.3Å; L266-E270 PolarHBondContact O-N 3.1Å; K267-E270 PolarHBondContact O-N 2.84Å; E270-L273 PolarHBondContact O-N 3.03Å; E270-R274 WeakPolarHBondContact O-CG 3.49Å; E270-R274 PolarHBondContact O-N 3.46Å
271	E	92.4	Very high	89.6	Confident	112 Å²	112	94.1 Å²	94.1	52%	0.523	40%	0.401	S	S	.	.	H	α-helix	trans	-63.1	-47.7	172.3	-75.9	169.8	-169.4	0	0	111.3	K267 Q268 L273 R274 T275	K267-E271 WeakPolarHBondContact O-CG 3.08Å; K267-E271 PolarHBondContact O-N 3.2Å; Q268-E271 PolarHBondContact O-N 3.32Å; E271-L273 VanDerWaalsContact C-N 3.34Å; E271-L273 PolarHBondContact O-N 2.98Å; E271-R274 WeakPolarHBondContact O-CB 3.4Å; E271-R274 PolarHBondContact O-N 3.33Å; E271-R274 VanDerWaalsContact O-N 3.15Å; E271-T275 PolarHBondContact O-N 3.09Å
272	R	91	Very high	89.4	Confident	131 Å²	131	87.4 Å²	87.4	49%	0.494	38%	0.378	S	S	.	.	H	α-helix	trans	-59.3	-44.3	175.8	-172.2	172.8	176.8	-178.7	-6	111.4	Q268 C269 R274 T275 L276	Q268-R272 WeakPolarHBondContact O-CB 3.48Å; Q268-R272 PolarHBondContact O-N 2.86Å; C269-R272 PolarHBondContact O-N 3.37Å; R272-R274 VanDerWaalsContact C-N 3.32Å; R272-R274 PolarHBondContact O-N 2.61Å; R272-T275 WeakPolarHBondContact CA-OG1 3.5Å; R272-T275 PolarHBondContact O-N 2.81Å; R272-T275 VanDerWaalsContact O-N 3.11Å; R272-T275 PolarHBondContact O-OG1 3.42Å; R272-L276 HydrophobicContact CG-CD1 4.09Å; R272-L276 HydrophobicContact CG-CG 4.39Å; R272-L276 WeakPolarHBondContact O-CG 3.44Å; R272-L276 PolarHBondContact O-N 2.83Å
273	L	92.1	Very high	89.1	Confident	19 Å²	19	85.5 Å²	85.5	10%	0.099	37%	0.368	C	S	.	.	H	α-helix	trans	-58.7	-41.8	175.9	-172.9	74.3	0	0	0	111.9	I238 V241 E242 I245 C269 E270 E271 T275 L276 R277	I238-L273 HydrophobicContact CG2-CD1 3.99Å; V241-L273 HydrophobicContact CG1-CB 4.1Å; V241-L273 HydrophobicContact CG1-CD1 4.27Å; E242-L273 HydrophobicContact CG-CD1 3.69Å; E242-L273 HydrophobicContact CG-CD2 4.36Å; I245-L273 HydrophobicContact CD1-CB 4.47Å; I245-L273 HydrophobicContact CD1-CD2 4.06Å; C269-L273 WeakPolarHBondContact O-CB 3.19Å; C269-L273 PolarHBondContact O-N 3.32Å; E270-L273 PolarHBondContact O-N 3.03Å; E271-L273 VanDerWaalsContact C-N 3.34Å; E271-L273 PolarHBondContact O-N 2.98Å; L273-T275 VanDerWaalsContact C-N 3.34Å; L273-T275 PolarHBondContact O-N 3.46Å; L273-L276 PolarHBondContact O-N 2.84Å; L273-R277 WeakPolarHBondContact O-CB 3.18Å; L273-R277 WeakPolarHBondContact O-CG 3.44Å; L273-R277 PolarHBondContact O-N 3.01Å
274	R	90	Very high	88.9	Confident	162 Å²	162	81.5 Å²	81.5	61%	0.611	36%	0.356	S	S	*	.	H	α-helix	trans	-60.9	-43.7	175	-72	174.3	-170.2	161.2	4	111.3	E270 E271 R272 K278	E270-R274 WeakPolarHBondContact O-CG 3.49Å; E270-R274 PolarHBondContact O-N 3.46Å; E271-R274 WeakPolarHBondContact O-CB 3.4Å; E271-R274 PolarHBondContact O-N 3.33Å; E271-R274 VanDerWaalsContact O-N 3.15Å; R272-R274 VanDerWaalsContact C-N 3.32Å; R272-R274 PolarHBondContact O-N 2.61Å; R274-K278 WeakPolarHBondContact O-CG 3.23Å; R274-K278 PolarHBondContact O-N 3.3Å
275	T	87.9	Confident	88.5	Confident	87 Å²	87	80 Å²	80	53%	0.534	35%	0.354	S	S	.	.	H	α-helix	trans	-64.5	-45.3	177.6	61.7	0	0	0	0	112	E271 R272 L273 R277 K278 R279	E271-T275 PolarHBondContact O-N 3.09Å; R272-T275 WeakPolarHBondContact CA-OG1 3.5Å; R272-T275 PolarHBondContact O-N 2.81Å; R272-T275 VanDerWaalsContact O-N 3.11Å; R272-T275 PolarHBondContact O-OG1 3.42Å; L273-T275 VanDerWaalsContact C-N 3.34Å; L273-T275 PolarHBondContact O-N 3.46Å; T275-R277 PolarHBondContact O-N 3.29Å; T275-K278 WeakPolarHBondContact O-CB 3.36Å; T275-K278 PolarHBondContact O-N 3.28Å; T275-R279 WeakPolarHBondContact O-CB 3.41Å; T275-R279 PolarHBondContact O-N 3.45Å
276	L	88.9	Confident	87.9	Confident	13 Å²	13	78.8 Å²	78.8	7%	0.068	35%	0.346	C	S	.	.	H	α-helix	trans	-63.1	-39.6	178	-67.9	170.4	0	0	0	112.3	N234 D237 I238 V241 R272 L273 R279 D280	N234-L276 PolarHBondContact ND2-O 2.88Å; N234-L276 VanDerWaalsContact OD1-CD2 3.26Å; N234-L276 WeakPolarHBondContact OD1-CD2 3.29Å; D237-L276 HydrophobicContact CB-CD1 4.06Å; D237-L276 HydrophobicContact CB-CD2 4.18Å; I238-L276 HydrophobicContact CD1-CB 4.23Å; I238-L276 HydrophobicContact CG1-CB 3.64Å; I238-L276 HydrophobicContact CG1-CD1 4.3Å; V241-L276 HydrophobicContact CG2-CD1 4.05Å; R272-L276 HydrophobicContact CG-CD1 4.09Å; R272-L276 HydrophobicContact CG-CG 4.39Å; R272-L276 WeakPolarHBondContact O-CG 3.44Å; R272-L276 PolarHBondContact O-N 2.83Å; L273-L276 PolarHBondContact O-N 2.84Å; L276-R279 WeakPolarHBondContact O-CB 3.27Å; L276-R279 PolarHBondContact O-N 3.02Å; L276-D280 PolarHBondContact O-N 3.42Å
277	R	89.6	Confident	87.3	Confident	122 Å²	122	80.6 Å²	80.6	46%	0.46	35%	0.354	S	S	.	.	H	α-helix	trans	-69.8	-32.7	174.8	-75	-175.6	-178.1	167.9	-0.5	113.4	I238 E242 L273 T275 R281	I238-R277 HydrophobicContact CD1-CG 4.27Å; E242-R277 IonicContact OE1-CZ 2.87Å; E242-R277 IonicContact OE1-NE 3.69Å; E242-R277 IonicContact OE1-NH2 3.96Å; E242-R277 PolarHBondContact OE1-NH2 2.85Å; L273-R277 WeakPolarHBondContact O-CB 3.18Å; L273-R277 WeakPolarHBondContact O-CG 3.44Å; L273-R277 PolarHBondContact O-N 3.01Å; T275-R277 PolarHBondContact O-N 3.29Å; R277-R281 WeakPolarHBondContact O-CG 3.06Å; R277-R281 PolarHBondContact O-N 2.95Å; R277-R281 PolarHBondContact O-NE 2.97Å
278	K	86.6	Confident	86.6	Confident	88 Å²	88	79.8 Å²	79.8	38%	0.383	36%	0.355	S	S	.	.	H	α-helix	trans	-62.8	-47.2	169.7	-76.1	-179.1	-179.3	-172.7	0	109.8	R274 T275 D280 R281 H282 D529	R274-K278 WeakPolarHBondContact O-CG 3.23Å; R274-K278 PolarHBondContact O-N 3.3Å; T275-K278 WeakPolarHBondContact O-CB 3.36Å; T275-K278 PolarHBondContact O-N 3.28Å; K278-D280 PolarHBondContact O-N 2.94Å; K278-R281 PolarHBondContact O-N 2.96Å; K278-H282 PolarHBondContact O-CD2 2.97Å; K278-H282 PolarHBondContact O-N 3.33Å; K278-D529 IonicContact NZ-OD2 3.88Å; K278-D529 PolarHBondContact NZ-OD2 3.21Å
279	R	84.8	Confident	85.9	Confident	74 Å²	74	75.2 Å²	75.2	28%	0.279	34%	0.338	S	S	.	.	H	α-helix	trans	-59.6	-42.4	178	-165.2	174	166.9	95.6	-0.1	112.6	T275 L276 H282 L283 S516 I518 D522	T275-R279 WeakPolarHBondContact O-CB 3.41Å; T275-R279 PolarHBondContact O-N 3.45Å; L276-R279 WeakPolarHBondContact O-CB 3.27Å; L276-R279 PolarHBondContact O-N 3.02Å; R279-H282 PolarHBondContact O-N 3.46Å; R279-L283 WeakPolarHBondContact O-CG 3.47Å; R279-L283 PolarHBondContact O-N 3.47Å; R279-S516 PolarHBondContact NH2-OG 3.46Å; R279-S516 VanDerWaalsContact NH2-OG 3.14Å; R279-I518 HydrophobicContact CG-CD1 3.17Å; R279-I518 VanDerWaalsContact NE-CD1 3.3Å; R279-D522 IonicContact CZ-OD2 3.59Å; R279-D522 IonicContact NH1-OD2 2.62Å; R279-D522 PolarHBondContact NH1-OD2 3.49Å
280	D	87	Confident	85	Confident	31 Å²	31	84.3 Å²	84.3	17%	0.166	37%	0.369	C	S	.	.	H	α-helix	trans	-61	-46.4	177.3	-173.1	56.2	0	0	0	112.5	R231 N234 I238 L276 K278 H282 L283 E284	R231-D280 WeakPolarHBondContact CG-OD1 3.41Å; R231-D280 IonicContact NE-OD1 2.82Å; N234-D280 WeakPolarHBondContact ND2-CB 3.47Å; N234-D280 PolarHBondContact ND2-N 3.41Å; I238-D280 HydrophobicContact CD1-CB 4.16Å; L276-D280 PolarHBondContact O-N 3.42Å; K278-D280 PolarHBondContact O-N 2.94Å; D280-H282 VanDerWaalsContact C-N 3.28Å; D280-H282 PolarHBondContact O-N 2.99Å; D280-L283 WeakPolarHBondContact O-CB 3.34Å; D280-L283 PolarHBondContact O-N 3.49Å; D280-L283 VanDerWaalsContact O-N 3.11Å; D280-E284 WeakPolarHBondContact O-CB 3.11Å; D280-E284 PolarHBondContact O-N 3.38Å
281	R	84.9	Confident	83.9	Confident	160 Å²	160	90.8 Å²	90.8	60%	0.604	39%	0.391	S	S	*	.	H	α-helix	trans	-59.6	-38.4	176.7	-72.4	-175.8	-71.5	178.4	1.7	112.2	R277 K278 F285	R277-R281 WeakPolarHBondContact O-CG 3.06Å; R277-R281 PolarHBondContact O-N 2.95Å; R277-R281 PolarHBondContact O-NE 2.97Å; K278-R281 PolarHBondContact O-N 2.96Å; R281-F285 PolarHBondContact O-N 3.14Å; R281-F285 VanDerWaalsContact O-N 3.15Å
282	H	82.9	Confident	82.8	Confident	57 Å²	57	88 Å²	88	26%	0.264	38%	0.381	S	S	.	.	H	α-helix	trans	-67.2	-43.1	174.3	-75.4	-64.2	0	0	0	112	K278 R279 D280 E284 F285 I286 I518	K278-H282 PolarHBondContact O-CD2 2.97Å; K278-H282 PolarHBondContact O-N 3.33Å; R279-H282 PolarHBondContact O-N 3.46Å; D280-H282 VanDerWaalsContact C-N 3.28Å; D280-H282 PolarHBondContact O-N 2.99Å; H282-E284 VanDerWaalsContact C-N 3.35Å; H282-E284 PolarHBondContact O-N 2.88Å; H282-F285 PolarHBondContact O-N 3.31Å; H282-I286 WeakPolarHBondContact O-CD1 3.34Å; H282-I286 WeakPolarHBondContact O-CG1 3.46Å; H282-I286 PolarHBondContact O-N 3.25Å; H282-I518 HydrophobicContact CB-CG2 4.48Å
283	L	83.4	Confident	81.9	Confident	0 Å²	0	88.9 Å²	88.9	0%	0	39%	0.389	C	S	.	.	H	α-helix	trans	-61.5	-42.7	176.6	-74.1	167.8	0	0	0	112.2	E230 R231 N234 R279 D280 I286 E287 I518	E230-L283 HydrophobicContact CB-CD1 4.38Å; E230-L283 HydrophobicContact CB-CD2 4.02Å; R231-L283 HydrophobicContact CB-CB 4.09Å; R231-L283 HydrophobicContact CB-CD1 4.11Å; R231-L283 HydrophobicContact CG-CB 4.15Å; R231-L283 HydrophobicContact CG-CD1 4.49Å; N234-L283 HydrophobicContact CB-CD1 4.04Å; R279-L283 WeakPolarHBondContact O-CG 3.47Å; R279-L283 PolarHBondContact O-N 3.47Å; D280-L283 WeakPolarHBondContact O-CB 3.34Å; D280-L283 PolarHBondContact O-N 3.49Å; D280-L283 VanDerWaalsContact O-N 3.11Å; L283-I286 PolarHBondContact O-N 2.78Å; L283-E287 VanDerWaalsContact O-CB 3.3Å; L283-E287 WeakPolarHBondContact O-CB 3.45Å; L283-E287 PolarHBondContact O-N 3.32Å; L283-I518 HydrophobicContact CD1-CD1 3.62Å; L283-I518 HydrophobicContact CD2-CD1 3.39Å; L283-I518 HydrophobicContact CD2-CG1 3.42Å; L283-I518 VanDerWaalsContact CD2-CG1 3.42Å; L283-I518 HydrophobicContact CG-CD1 3.33Å; L283-I518 HydrophobicContact CG-CG1 3.93Å
284	E	84.3	Confident	81.2	Confident	80 Å²	80	93.5 Å²	93.5	37%	0.374	41%	0.409	S	S	.	.	H	α-helix	trans	-61.4	-43.5	177	179.7	166.6	-129.6	0	0	112	R231 D280 H282 I286 E287 N288	R231-E284 IonicContact CZ-OE1 2.62Å; R231-E284 IonicContact NH1-OE1 3.28Å; R231-E284 IonicContact NH2-OE1 3.51Å; R231-E284 PolarHBondContact NH2-OE1 3.34Å; R231-E284 IonicContact NH2-OE2 3.99Å; D280-E284 WeakPolarHBondContact O-CB 3.11Å; D280-E284 PolarHBondContact O-N 3.38Å; H282-E284 VanDerWaalsContact C-N 3.35Å; H282-E284 PolarHBondContact O-N 2.88Å; E284-I286 VanDerWaalsContact C-N 3.33Å; E284-I286 PolarHBondContact O-N 3.44Å; E284-E287 PolarHBondContact O-N 3.29Å; E284-N288 WeakPolarHBondContact O-CB 3.48Å; E284-N288 PolarHBondContact O-N 2.95Å; E284-N288 PolarHBondContact O-ND2 2.74Å
285	F	81.6	Confident	80.3	Confident	153 Å²	153	88.2 Å²	88.2	67%	0.671	40%	0.395	S	S	*	.	H	α-helix	trans	-61.6	-42.1	175.5	179.7	-98.5	0	0	0	111.9	R281 H282 S289	R281-F285 PolarHBondContact O-N 3.14Å; R281-F285 VanDerWaalsContact O-N 3.15Å; H282-F285 PolarHBondContact O-N 3.31Å; F285-S289 WeakPolarHBondContact O-CB 3.48Å; F285-S289 PolarHBondContact O-N 2.89Å; F285-S289 VanDerWaalsContact O-N 3.16Å
286	I	77.8	Confident	79.5	Confident	18 Å²	18	86.1 Å²	86.1	9%	0.092	39%	0.391	C	S	.	.	H	α-helix	trans	-68.3	-43.2	179.4	-65.6	165.1	0	0	0	110.7	A227 H282 L283 E284 S289 T292 V517 V521	A227-I286 HydrophobicContact CB-CG2 4.13Å; H282-I286 WeakPolarHBondContact O-CD1 3.34Å; H282-I286 WeakPolarHBondContact O-CG1 3.46Å; H282-I286 PolarHBondContact O-N 3.25Å; L283-I286 PolarHBondContact O-N 2.78Å; E284-I286 VanDerWaalsContact C-N 3.33Å; E284-I286 PolarHBondContact O-N 3.44Å; I286-S289 PolarHBondContact O-N 2.83Å; I286-T292 HydrophobicContact CG2-CG2 3.72Å; I286-T292 WeakPolarHBondContact O-CB 3.23Å; I286-T292 WeakPolarHBondContact O-CG2 3.38Å; I286-T292 PolarHBondContact O-OG1 3.13Å; I286-V517 HydrophobicContact CD1-CG1 4.18Å; I286-V517 HydrophobicContact CG2-CG1 3.75Å; I286-V521 HydrophobicContact CD1-CB 4.17Å; I286-V521 HydrophobicContact CD1-CG1 4.27Å; I286-V521 HydrophobicContact CD1-CG2 3.75Å
287	E	79.2	Confident	79	Confident	61 Å²	61	88.9 Å²	88.9	29%	0.285	42%	0.416	S	S	.	.	H	α-helix	trans	-61.8	-43	178.3	-176.1	177.3	-163.2	0	0	112	A228 R231 L283 E284 S289	A228-E287 WeakPolarHBondContact CB-OE1 3.14Å; R231-E287 WeakPolarHBondContact CD-OE2 3.45Å; R231-E287 IonicContact CZ-OE2 3.57Å; R231-E287 IonicContact NE-OE2 3.6Å; R231-E287 IonicContact NH1-OE2 3.23Å; R231-E287 PolarHBondContact NH1-OE2 2.95Å; L283-E287 VanDerWaalsContact O-CB 3.3Å; L283-E287 WeakPolarHBondContact O-CB 3.45Å; L283-E287 PolarHBondContact O-N 3.32Å; E284-E287 PolarHBondContact O-N 3.29Å; E287-S289 VanDerWaalsContact C-N 3.34Å; E287-S289 PolarHBondContact O-N 3.48Å
288	N	76.8	Confident	78.6	Confident	102 Å²	102	85.9 Å²	85.9	55%	0.545	41%	0.409	S	S	.	.	H	α-helix	trans	-80.9	-12.5	-177.3	-73.2	-29.8	0	0	0	114	E284 W290	E284-N288 WeakPolarHBondContact O-CB 3.48Å; E284-N288 PolarHBondContact O-N 2.95Å; E284-N288 PolarHBondContact O-ND2 2.74Å; N288-W290 PolarHBondContact O-N 3.49Å
289	S	78.2	Confident	78.4	Confident	32 Å²	32	85 Å²	85	22%	0.224	40%	0.403	C	S	.	.			trans	-68.8	128.4	-178.1	-169.5	0	0	0	0	112.2	F285 I286 E287 W291 T292	F285-S289 WeakPolarHBondContact O-CB 3.48Å; F285-S289 PolarHBondContact O-N 2.89Å; F285-S289 VanDerWaalsContact O-N 3.16Å; I286-S289 PolarHBondContact O-N 2.83Å; E287-S289 VanDerWaalsContact C-N 3.34Å; E287-S289 PolarHBondContact O-N 3.48Å; S289-W291 PolarHBondContact O-N 3.25Å; S289-W291 VanDerWaalsContact O-N 3.12Å; S289-T292 PolarHBondContact O-N 3.15Å; S289-T292 VanDerWaalsContact O-N 3.07Å; S289-T292 PolarHBondContact O-OG1 3.29Å
290	W	73.6	Confident	78.5	Confident	217 Å²	217	85.1 Å²	85.1	82%	0.822	41%	0.414	S	S	*	.	H	α-helix	trans	-59.6	-26.5	175	-69	3.7	0	0	0	112.8	N288 T292 K293 F294	N288-W290 PolarHBondContact O-N 3.49Å; W290-T292 VanDerWaalsContact C-N 3.32Å; W290-T292 PolarHBondContact O-N 3.46Å; W290-K293 PolarHBondContact O-N 3.03Å; W290-F294 PolarHBondContact O-N 3.41Å; W290-F294 VanDerWaalsContact O-N 3.11Å
291	W	68.3	Low	78.5	Confident	188 Å²	188	88 Å²	88	71%	0.712	43%	0.428	S	S	*	.	H	α-helix	trans	-65	-30.8	176.1	-87.8	94.7	0	0	0	113.5	S289 C295	S289-W291 PolarHBondContact O-N 3.25Å; S289-W291 VanDerWaalsContact O-N 3.12Å; W291-C295 WeakPolarHBondContact O-CB 3.33Å; W291-C295 PolarHBondContact O-N 3.11Å; W291-C295 PolarHBondContact O-SG 3.29Å
292	T	69.9	Low	78.6	Confident	52 Å²	52	84 Å²	84	32%	0.319	42%	0.415	S	S	.	.	H	α-helix	trans	-76.8	-36.5	179	56.8	0	0	0	0	111.7	I286 S289 W290 C295 G296	I286-T292 HydrophobicContact CG2-CG2 3.72Å; I286-T292 WeakPolarHBondContact O-CB 3.23Å; I286-T292 WeakPolarHBondContact O-CG2 3.38Å; I286-T292 PolarHBondContact O-OG1 3.13Å; S289-T292 PolarHBondContact O-N 3.15Å; S289-T292 VanDerWaalsContact O-N 3.07Å; S289-T292 PolarHBondContact O-OG1 3.29Å; W290-T292 VanDerWaalsContact C-N 3.32Å; W290-T292 PolarHBondContact O-N 3.46Å; T292-C295 PolarHBondContact O-N 2.91Å; T292-G296 PolarHBondContact O-N 3.48Å
293	K	73.1	Confident	79	Confident	150 Å²	150	84.1 Å²	84.1	65%	0.652	42%	0.417	S	S	*	.	H	α-helix	trans	-60.9	-46.6	170.2	-65.3	-174.3	179.4	178.8	0	111.7	W290 G296 A297	W290-K293 PolarHBondContact O-N 3.03Å; K293-G296 PolarHBondContact O-N 2.97Å; K293-A297 PolarHBondContact O-N 2.93Å; K293-A297 VanDerWaalsContact O-N 3.08Å
294	F	76.4	Confident	79.4	Confident	117 Å²	117	89.1 Å²	89.1	51%	0.513	44%	0.443	S	S	.	.	H	α-helix	trans	-63.5	-43.1	174.4	-178.9	-105.2	0	0	0	112.4	W290 G296 A297 L298	W290-F294 PolarHBondContact O-N 3.41Å; W290-F294 VanDerWaalsContact O-N 3.11Å; F294-G296 VanDerWaalsContact C-N 3.25Å; F294-G296 PolarHBondContact O-N 3.36Å; F294-A297 PolarHBondContact O-N 2.79Å; F294-L298 HydrophobicContact CD1-CD1 4.04Å; F294-L298 HydrophobicContact CE1-CD1 3.52Å; F294-L298 HydrophobicContact CE1-CG 4.31Å; F294-L298 HydrophobicContact CZ-CD1 3.95Å; F294-L298 HydrophobicContact CZ-CG 4.38Å; F294-L298 PolarHBondContact O-N 3.27Å; F294-L298 VanDerWaalsContact O-N 3.15Å
295	C	70.5	Confident	79.7	Confident	50 Å²	50	92 Å²	92	34%	0.338	45%	0.451	S	S	.	.	H	α-helix	trans	-64	-29.5	174.9	-78	0	0	0	0	113.6	W291 T292	W291-C295 WeakPolarHBondContact O-CB 3.33Å; W291-C295 PolarHBondContact O-N 3.11Å; W291-C295 PolarHBondContact O-SG 3.29Å; T292-C295 PolarHBondContact O-N 2.91Å
296	G	71.2	Confident	80.2	Confident	43 Å²	43	84.7 Å²	84.7	44%	0.443	42%	0.419	S	S	.	.	H	α-helix	trans	-67.1	-43.2	171.8	0	0	0	0	0	111.9	T292 K293 F294 L298 R299	T292-G296 PolarHBondContact O-N 3.48Å; K293-G296 PolarHBondContact O-N 2.97Å; F294-G296 VanDerWaalsContact C-N 3.25Å; F294-G296 PolarHBondContact O-N 3.36Å; G296-L298 VanDerWaalsContact C-N 3.27Å; G296-L298 PolarHBondContact O-N 3.18Å; G296-R299 WeakPolarHBondContact O-CB 3.18Å; G296-R299 PolarHBondContact O-N 3.42Å
297	A	78.8	Confident	80.9	Confident	72 Å²	72	88 Å²	88	60%	0.595	44%	0.436	S	S	*	.	H	α-helix	trans	-63.3	-31.4	174.8	0	0	0	0	0	113	K293 F294 R299 P300	K293-A297 PolarHBondContact O-N 2.93Å; K293-A297 VanDerWaalsContact O-N 3.08Å; F294-A297 PolarHBondContact O-N 2.79Å; A297-R299 PolarHBondContact O-N 3.26Å; A297-P300 WeakPolarHBondContact O-CD 3.31Å
298	L	80.6	Confident	81.6	Confident	59 Å²	59	89.9 Å²	89.9	31%	0.309	44%	0.443	S	S	.	.	T	Hydrogen-bonded Turn	trans	-78.3	0.8	173.6	-66.4	175.9	0	0	0	113.9	F294 G296 L301 K302	F294-L298 HydrophobicContact CD1-CD1 4.04Å; F294-L298 HydrophobicContact CE1-CD1 3.52Å; F294-L298 HydrophobicContact CE1-CG 4.31Å; F294-L298 HydrophobicContact CZ-CD1 3.95Å; F294-L298 HydrophobicContact CZ-CG 4.38Å; F294-L298 PolarHBondContact O-N 3.27Å; F294-L298 VanDerWaalsContact O-N 3.15Å; G296-L298 VanDerWaalsContact C-N 3.27Å; G296-L298 PolarHBondContact O-N 3.18Å; L298-L301 HydrophobicContact CD2-CD1 3.77Å; L298-L301 PolarHBondContact O-N 3.03Å; L298-K302 WeakPolarHBondContact O-CG 3.45Å; L298-K302 PolarHBondContact O-N 2.93Å
299	R	83.6	Confident	82.4	Confident	68 Å²	68	86.9 Å²	86.9	26%	0.257	43%	0.425	S	S	.	.	H	α-helix	trans	-61.8	-46.7	-178.6	-171.3	58.8	-179.1	-122.6	-0.3	114.8	I221 K222 G223 G296 A297 L301 K302 I303	I221-R299 PolarHBondContact O-NH2 3.27Å; K222-R299 PolarHBondContact O-NH2 2.96Å; G223-R299 VanDerWaalsContact CA-NH2 3.27Å; G223-R299 VanDerWaalsContact N-NH2 3.17Å; G296-R299 WeakPolarHBondContact O-CB 3.18Å; G296-R299 PolarHBondContact O-N 3.42Å; A297-R299 PolarHBondContact O-N 3.26Å; R299-L301 VanDerWaalsContact C-N 3.26Å; R299-L301 PolarHBondContact O-N 3.02Å; R299-K302 WeakPolarHBondContact O-CB 3.39Å; R299-K302 PolarHBondContact O-N 3.21Å; R299-K302 VanDerWaalsContact O-N 3.14Å; R299-I303 HydrophobicContact CG-CD1 4.28Å; R299-I303 WeakPolarHBondContact O-CG1 3.47Å; R299-I303 PolarHBondContact O-N 2.85Å; R299-I303 VanDerWaalsContact O-N 3.07Å
300	P	87	Confident	83.1	Confident	78 Å²	78	87.7 Å²	87.7	51%	0.506	43%	0.427	S	S	.	.	H	α-helix	trans	-57.3	-40.7	175.4	20.9	-34	0	0	0	111.9	A297 K302 I303 I304	A297-P300 WeakPolarHBondContact O-CD 3.31Å; P300-K302 PolarHBondContact O-N 3.28Å; P300-I303 PolarHBondContact O-N 3.02Å; P300-I304 WeakPolarHBondContact O-CG1 3.37Å; P300-I304 PolarHBondContact O-N 3.49Å
301	L	86.9	Confident	84	Confident	90 Å²	90	82.4 Å²	82.4	47%	0.471	41%	0.414	S	S	.	.	H	α-helix	trans	-62.2	-42.5	175.8	-67.3	175.5	0	0	0	112	L298 R299 I303 I304 W305	L298-L301 HydrophobicContact CD2-CD1 3.77Å; L298-L301 PolarHBondContact O-N 3.03Å; R299-L301 VanDerWaalsContact C-N 3.26Å; R299-L301 PolarHBondContact O-N 3.02Å; L301-I303 VanDerWaalsContact C-N 3.29Å; L301-I303 PolarHBondContact O-N 2.7Å; L301-I304 HydrophobicContact CD2-CD1 4.46Å; L301-I304 PolarHBondContact O-N 2.93Å; L301-W305 PolarHBondContact O-N 2.65Å
302	K	87.3	Confident	85.2	Confident	76 Å²	76	74.8 Å²	74.8	33%	0.33	39%	0.388	S	S	.	.	H	α-helix	trans	-60.6	-37.7	175.4	-71.5	171.7	-178.1	166	0	112.4	L298 R299 P300 G306	L298-K302 WeakPolarHBondContact O-CG 3.45Å; L298-K302 PolarHBondContact O-N 2.93Å; R299-K302 WeakPolarHBondContact O-CB 3.39Å; R299-K302 PolarHBondContact O-N 3.21Å; R299-K302 VanDerWaalsContact O-N 3.14Å; P300-K302 PolarHBondContact O-N 3.28Å; K302-G306 PolarHBondContact O-N 3.31Å
303	I	89.8	Confident	86.3	Confident	60 Å²	60	72.4 Å²	72.4	31%	0.308	37%	0.374	S	S	.	.	H	α-helix	trans	-68.2	-44.8	176.8	-64.4	168.9	0	0	0	110.4	R299 P300 L301 W305 G306 I307	R299-I303 HydrophobicContact CG-CD1 4.28Å; R299-I303 WeakPolarHBondContact O-CG1 3.47Å; R299-I303 PolarHBondContact O-N 2.85Å; R299-I303 VanDerWaalsContact O-N 3.07Å; P300-I303 PolarHBondContact O-N 3.02Å; L301-I303 VanDerWaalsContact C-N 3.29Å; L301-I303 PolarHBondContact O-N 2.7Å; I303-W305 VanDerWaalsContact C-N 3.35Å; I303-W305 PolarHBondContact O-N 3.43Å; I303-G306 WeakPolarHBondContact O-CA 3.43Å; I303-G306 PolarHBondContact O-N 3.06Å; I303-G306 VanDerWaalsContact O-N 3.09Å; I303-I307 HydrophobicContact CG2-CD1 4.05Å; I303-I307 WeakPolarHBondContact O-CG1 3.45Å; I303-I307 PolarHBondContact O-N 3.39Å
304	I	92.2	Very high	87.3	Confident	105 Å²	105	68.7 Å²	68.7	54%	0.538	36%	0.36	S	S	.	.	H	α-helix	trans	-57.9	-48.1	176.1	-67.6	164.9	0	0	0	110.5	P300 L301 G306 I307 F308	P300-I304 WeakPolarHBondContact O-CG1 3.37Å; P300-I304 PolarHBondContact O-N 3.49Å; L301-I304 HydrophobicContact CD2-CD1 4.46Å; L301-I304 PolarHBondContact O-N 2.93Å; I304-G306 VanDerWaalsContact C-N 3.3Å; I304-G306 PolarHBondContact O-N 3.36Å; I304-I307 PolarHBondContact O-N 2.96Å; I304-F308 WeakPolarHBondContact O-CB 3.37Å; I304-F308 PolarHBondContact O-N 3.43Å
305	W	90.6	Very high	88	Confident	140 Å²	140	66 Å²	66	53%	0.53	35%	0.351	S	S	.	.	H	α-helix	trans	-60.1	-39.6	174.4	-83.1	108.3	0	0	0	112.4	L301 I303 F308 F309	L301-W305 PolarHBondContact O-N 2.65Å; I303-W305 VanDerWaalsContact C-N 3.35Å; I303-W305 PolarHBondContact O-N 3.43Å; W305-F308 AromaticContact CE3-CD1 3.99Å; W305-F308 HydrophobicContact CE3-CD1 3.99Å; W305-F308 AromaticContact CZ3-CD1 3.98Å; W305-F308 HydrophobicContact CZ3-CD1 3.98Å; W305-F308 HydrophobicContact CZ3-CE1 4.13Å; W305-F308 PolarHBondContact O-N 3.47Å; W305-F309 HydrophobicContact CB-CE2 4.45Å; W305-F309 AromaticContact CE3-CE2 3.94Å; W305-F309 HydrophobicContact CE3-CE2 3.94Å; W305-F309 AromaticContact CE3-CZ 3.99Å; W305-F309 HydrophobicContact CE3-CZ 3.99Å; W305-F309 HydrophobicContact CZ3-CZ 4.31Å; W305-F309 WeakPolarHBondContact O-CD2 3.11Å; W305-F309 WeakPolarHBondContact O-CG 3.45Å; W305-F309 PolarHBondContact O-N 3.15Å
306	G	92.3	Very high	89.1	Confident	0 Å²	0	63.9 Å²	63.9	0%	0	34%	0.336	C	S	.	.	H	α-helix	trans	-59.8	-48.4	174.3	0	0	0	0	0	112.6	P217 K302 I303 I304 F309 I310	P217-G306 VanDerWaalsContact CB-O 3.28Å; P217-G306 WeakPolarHBondContact CB-O 3.4Å; K302-G306 PolarHBondContact O-N 3.31Å; I303-G306 WeakPolarHBondContact O-CA 3.43Å; I303-G306 PolarHBondContact O-N 3.06Å; I303-G306 VanDerWaalsContact O-N 3.09Å; I304-G306 VanDerWaalsContact C-N 3.3Å; I304-G306 PolarHBondContact O-N 3.36Å; G306-F309 PolarHBondContact O-N 2.98Å; G306-I310 WeakPolarHBondContact O-CG1 3.26Å; G306-I310 PolarHBondContact O-N 3.43Å; G306-I310 VanDerWaalsContact O-N 3.08Å
307	I	93.1	Very high	90.2	Very high	89 Å²	89	62.8 Å²	62.8	46%	0.456	32%	0.32	S	S	.	.	H	α-helix	trans	-61.7	-45.7	177.1	-65.7	167.5	0	0	0	110.5	I221 I303 I304 F309 I310 L311	I221-I307 HydrophobicContact CD1-CG1 4.29Å; I303-I307 HydrophobicContact CG2-CD1 4.05Å; I303-I307 WeakPolarHBondContact O-CG1 3.45Å; I303-I307 PolarHBondContact O-N 3.39Å; I304-I307 PolarHBondContact O-N 2.96Å; I307-F309 VanDerWaalsContact C-N 3.33Å; I307-F309 PolarHBondContact O-N 2.87Å; I307-I310 PolarHBondContact O-N 2.92Å; I307-I310 VanDerWaalsContact O-N 3.13Å; I307-L311 HydrophobicContact CG2-CD1 4.35Å; I307-L311 PolarHBondContact O-N 3.05Å
308	F	92.8	Very high	90.9	Very high	100 Å²	100	63.7 Å²	63.7	44%	0.439	31%	0.314	S	S	.	.	H	α-helix	trans	-55.7	-47.2	176.2	174.2	-100.5	0	0	0	111.8	I304 W305 I310 L311 V312	I304-F308 WeakPolarHBondContact O-CB 3.37Å; I304-F308 PolarHBondContact O-N 3.43Å; W305-F308 AromaticContact CE3-CD1 3.99Å; W305-F308 HydrophobicContact CE3-CD1 3.99Å; W305-F308 AromaticContact CZ3-CD1 3.98Å; W305-F308 HydrophobicContact CZ3-CD1 3.98Å; W305-F308 HydrophobicContact CZ3-CE1 4.13Å; W305-F308 PolarHBondContact O-N 3.47Å; F308-I310 VanDerWaalsContact C-N 3.31Å; F308-I310 PolarHBondContact O-N 2.92Å; F308-L311 PolarHBondContact O-N 3.35Å; F308-V312 HydrophobicContact CD1-CG2 4.34Å; F308-V312 HydrophobicContact CD2-CG2 4.48Å; F308-V312 HydrophobicContact CE1-CG2 3.89Å; F308-V312 HydrophobicContact CE2-CG2 4.04Å; F308-V312 HydrophobicContact CZ-CG2 3.72Å; F308-V312 WeakPolarHBondContact O-CG2 3.5Å; F308-V312 PolarHBondContact O-N 3.15Å
309	F	93.4	Very high	91.4	Very high	38 Å²	38	60.9 Å²	60.9	17%	0.167	30%	0.299	C	S	.	.	H	α-helix	trans	-66.7	-28.5	178.3	-74.6	-50.4	0	0	0	113.8	L216 P217 L220 W305 G306 I307 A313 Y373	L216-F309 HydrophobicContact CD2-CB 4.27Å; L216-F309 HydrophobicContact CD2-CD2 3.6Å; L216-F309 HydrophobicContact CD2-CE2 4.06Å; L216-F309 HydrophobicContact CD2-CG 3.97Å; P217-F309 HydrophobicContact CB-CB 3.95Å; P217-F309 HydrophobicContact CG-CB 4.47Å; L220-F309 HydrophobicContact CD1-CD2 3.87Å; L220-F309 HydrophobicContact CD1-CE2 4.18Å; W305-F309 HydrophobicContact CB-CE2 4.45Å; W305-F309 AromaticContact CE3-CE2 3.94Å; W305-F309 HydrophobicContact CE3-CE2 3.94Å; W305-F309 AromaticContact CE3-CZ 3.99Å; W305-F309 HydrophobicContact CE3-CZ 3.99Å; W305-F309 HydrophobicContact CZ3-CZ 4.31Å; W305-F309 WeakPolarHBondContact O-CD2 3.11Å; W305-F309 WeakPolarHBondContact O-CG 3.45Å; W305-F309 PolarHBondContact O-N 3.15Å; G306-F309 PolarHBondContact O-N 2.98Å; I307-F309 VanDerWaalsContact C-N 3.33Å; I307-F309 PolarHBondContact O-N 2.87Å; F309-A313 WeakPolarHBondContact O-CB 3.36Å; F309-A313 PolarHBondContact O-N 3.11Å; F309-Y373 HydrophobicContact CB-CE2 4.45Å; F309-Y373 AromaticContact CD1-CD2 3.66Å; F309-Y373 HydrophobicContact CD1-CD2 3.66Å; F309-Y373 AromaticContact CD1-CE2 3.54Å; F309-Y373 HydrophobicContact CD1-CE2 3.54Å; F309-Y373 AromaticContact CE1-CD2 3.85Å; F309-Y373 HydrophobicContact CE1-CD2 3.85Å; F309-Y373 HydrophobicContact CE1-CE2 4.2Å; F309-Y373 HydrophobicContact CG-CE2 4.34Å
310	I	93.3	Very high	91.9	Very high	49 Å²	49	57.7 Å²	57.7	25%	0.251	29%	0.287	S	S	.	.	H	α-helix	trans	-66.7	-46.3	170.2	-65.5	-176.9	0	0	0	110.5	P217 L218 I221 G306 I307 F308 V312 A313 L314	P217-I310 HydrophobicContact CB-CD1 4.2Å; P217-I310 HydrophobicContact CB-CG1 3.43Å; P217-I310 VanDerWaalsContact CB-CG1 3.43Å; P217-I310 HydrophobicContact CG-CG1 3.8Å; L218-I310 HydrophobicContact CD2-CD1 4.13Å; I221-I310 HydrophobicContact CD1-CD1 3.53Å; I221-I310 HydrophobicContact CD1-CG1 4.45Å; G306-I310 WeakPolarHBondContact O-CG1 3.26Å; G306-I310 PolarHBondContact O-N 3.43Å; G306-I310 VanDerWaalsContact O-N 3.08Å; I307-I310 PolarHBondContact O-N 2.92Å; I307-I310 VanDerWaalsContact O-N 3.13Å; F308-I310 VanDerWaalsContact C-N 3.31Å; F308-I310 PolarHBondContact O-N 2.92Å; I310-V312 VanDerWaalsContact C-N 3.31Å; I310-V312 PolarHBondContact O-N 3.46Å; I310-A313 WeakPolarHBondContact O-CB 3.08Å; I310-A313 PolarHBondContact O-N 3.35Å; I310-L314 HydrophobicContact CG2-CD1 3.97Å; I310-L314 HydrophobicContact CG2-CG 4.28Å; I310-L314 WeakPolarHBondContact O-CG 3.18Å; I310-L314 PolarHBondContact O-N 3.12Å
311	L	93.3	Very high	92.2	Very high	107 Å²	107	58.4 Å²	58.4	56%	0.56	28%	0.282	S	S	*	.	H	α-helix	trans	-60.3	-43.9	179.3	-68.1	173.1	0	0	0	111.3	I307 F308 L314 L315	I307-L311 HydrophobicContact CG2-CD1 4.35Å; I307-L311 PolarHBondContact O-N 3.05Å; F308-L311 PolarHBondContact O-N 3.35Å; L311-L314 PolarHBondContact O-N 3.1Å; L311-L315 PolarHBondContact O-N 3.18Å
312	V	92.6	Very high	92.4	Very high	27 Å²	27	56 Å²	56	16%	0.164	27%	0.27	C	S	.	.	H	α-helix	trans	-62.7	-43.2	174.7	171.5	0	0	0	0	111.4	F308 I310 L314 L315 F316 Y373	F308-V312 HydrophobicContact CD1-CG2 4.34Å; F308-V312 HydrophobicContact CD2-CG2 4.48Å; F308-V312 HydrophobicContact CE1-CG2 3.89Å; F308-V312 HydrophobicContact CE2-CG2 4.04Å; F308-V312 HydrophobicContact CZ-CG2 3.72Å; F308-V312 WeakPolarHBondContact O-CG2 3.5Å; F308-V312 PolarHBondContact O-N 3.15Å; I310-V312 VanDerWaalsContact C-N 3.31Å; I310-V312 PolarHBondContact O-N 3.46Å; V312-L314 PolarHBondContact O-N 3.18Å; V312-L315 WeakPolarHBondContact O-CB 3.44Å; V312-L315 PolarHBondContact O-N 3.08Å; V312-F316 HydrophobicContact CG1-CD2 3.91Å; V312-F316 HydrophobicContact CG1-CE2 3.29Å; V312-F316 HydrophobicContact CG1-CZ 3.9Å; V312-F316 VanDerWaalsContact O-CD2 3.27Å; V312-F316 WeakPolarHBondContact O-CD2 3.26Å; V312-F316 PolarHBondContact O-N 3.21Å; V312-F316 VanDerWaalsContact O-N 3.08Å; V312-Y373 HydrophobicContact CG1-CD1 4.44Å; V312-Y373 HydrophobicContact CG1-CD2 4.15Å; V312-Y373 HydrophobicContact CG1-CE1 4.31Å; V312-Y373 HydrophobicContact CG1-CE2 4.01Å; V312-Y373 HydrophobicContact CG1-CG 4.34Å
313	A	94.1	Very high	92.4	Very high	2 Å²	2	52.7 Å²	52.7	2%	0.017	26%	0.257	C	S	.	.	H	α-helix	trans	-59.6	-46.4	175.7	0	0	0	0	0	111.6	F309 I310 L315 F316 I317 Y373 F502	F309-A313 WeakPolarHBondContact O-CB 3.36Å; F309-A313 PolarHBondContact O-N 3.11Å; I310-A313 WeakPolarHBondContact O-CB 3.08Å; I310-A313 PolarHBondContact O-N 3.35Å; A313-L315 VanDerWaalsContact C-N 3.35Å; A313-L315 PolarHBondContact O-N 3.11Å; A313-F316 PolarHBondContact O-N 3.44Å; A313-I317 WeakPolarHBondContact O-CG1 3.41Å; A313-I317 PolarHBondContact O-N 3.39Å; A313-Y373 WeakPolarHBondContact CB-OH 3.25Å; A313-F502 HydrophobicContact CB-CE2 4.08Å; A313-F502 HydrophobicContact CB-CZ 4.18Å
314	L	93.1	Very high	92.4	Very high	72 Å²	72	49.9 Å²	49.9	38%	0.377	24%	0.242	S	C	.	.	H	α-helix	trans	-62.7	-40.8	178.1	-70.5	174.2	0	0	0	111.8	I310 L311 V312 F316 I317 I318	I310-L314 HydrophobicContact CG2-CD1 3.97Å; I310-L314 HydrophobicContact CG2-CG 4.28Å; I310-L314 WeakPolarHBondContact O-CG 3.18Å; I310-L314 PolarHBondContact O-N 3.12Å; L311-L314 PolarHBondContact O-N 3.1Å; V312-L314 PolarHBondContact O-N 3.18Å; L314-F316 VanDerWaalsContact C-N 3.34Å; L314-F316 PolarHBondContact O-N 2.89Å; L314-I317 PolarHBondContact O-N 2.88Å; L314-I318 WeakPolarHBondContact O-CB 3.33Å; L314-I318 VanDerWaalsContact O-CG1 3.25Å; L314-I318 WeakPolarHBondContact O-CG1 3.45Å; L314-I318 PolarHBondContact O-N 3.42Å
315	L	92.6	Very high	92.2	Very high	60 Å²	60	47.4 Å²	47.4	31%	0.314	23%	0.23	S	C	.	.	H	α-helix	trans	-57	-47.2	174.3	180	68.5	0	0	0	111.2	L311 V312 A313 S319 P348 L349	L311-L315 PolarHBondContact O-N 3.18Å; V312-L315 WeakPolarHBondContact O-CB 3.44Å; V312-L315 PolarHBondContact O-N 3.08Å; A313-L315 VanDerWaalsContact C-N 3.35Å; A313-L315 PolarHBondContact O-N 3.11Å; L315-S319 VanDerWaalsContact O-CB 3.29Å; L315-S319 WeakPolarHBondContact O-CB 3.47Å; L315-S319 PolarHBondContact O-N 2.93Å; L315-S319 PolarHBondContact O-OG 3.05Å; L315-P348 HydrophobicContact CD1-CB 4.06Å; L315-P348 HydrophobicContact CD1-CG 3.96Å; L315-L349 HydrophobicContact CD2-CD2 3.96Å; L315-L349 HydrophobicContact CD2-CG 4.43Å; L315-L349 HydrophobicContact CG-CD2 4.43Å; L315-L349 HydrophobicContact CG-CG 4.37Å
316	F	93	Very high	92	Very high	6 Å²	6	40.9 Å²	40.9	3%	0.026	21%	0.205	C	C	.	.	H	α-helix	trans	-65.1	-42.4	177.6	-67.8	-45.4	0	0	0	112.7	V312 A313 L314 S319 L320 L349 I370 Y373 F374 L428	V312-F316 HydrophobicContact CG1-CD2 3.91Å; V312-F316 HydrophobicContact CG1-CE2 3.29Å; V312-F316 HydrophobicContact CG1-CZ 3.9Å; V312-F316 VanDerWaalsContact O-CD2 3.27Å; V312-F316 WeakPolarHBondContact O-CD2 3.26Å; V312-F316 PolarHBondContact O-N 3.21Å; V312-F316 VanDerWaalsContact O-N 3.08Å; A313-F316 PolarHBondContact O-N 3.44Å; L314-F316 VanDerWaalsContact C-N 3.34Å; L314-F316 PolarHBondContact O-N 2.89Å; F316-S319 PolarHBondContact O-N 3.45Å; F316-L320 WeakPolarHBondContact O-CB 3.25Å; F316-L320 WeakPolarHBondContact O-CG 3.39Å; F316-L320 PolarHBondContact O-N 2.88Å; F316-L349 HydrophobicContact CD1-CD1 3.6Å; F316-L349 HydrophobicContact CE1-CD1 3.77Å; F316-I370 HydrophobicContact CE1-CD1 4.22Å; F316-I370 HydrophobicContact CE1-CG1 3.98Å; F316-I370 HydrophobicContact CE1-CG2 3.9Å; F316-I370 HydrophobicContact CZ-CB 4.21Å; F316-I370 HydrophobicContact CZ-CG1 3.8Å; F316-I370 HydrophobicContact CZ-CG2 3.79Å; F316-Y373 AromaticContact CD2-CD1 3.98Å; F316-Y373 HydrophobicContact CD2-CD1 3.98Å; F316-Y373 AromaticContact CD2-CE1 3.61Å; F316-Y373 HydrophobicContact CD2-CE1 3.61Å; F316-Y373 AromaticContact CE2-CD1 3.36Å; F316-Y373 HydrophobicContact CE2-CD1 3.36Å; F316-Y373 AromaticContact CE2-CE1 3.45Å; F316-Y373 HydrophobicContact CE2-CE1 3.45Å; F316-Y373 VanDerWaalsContact CE2-CE1 3.45Å; F316-Y373 HydrophobicContact CE2-CG 4.14Å; F316-Y373 HydrophobicContact CZ-CD1 4.34Å; F316-F374 HydrophobicContact CD2-CZ 4.36Å; F316-F374 HydrophobicContact CG-CZ 4.42Å; F316-L428 HydrophobicContact CB-CD2 4.21Å; F316-L428 HydrophobicContact CD1-CD1 3.85Å; F316-L428 HydrophobicContact CD1-CD2 3.8Å; F316-L428 HydrophobicContact CE1-CD1 4.12Å; F316-L428 HydrophobicContact CG-CD2 4.42Å
317	I	94.1	Very high	91.6	Very high	20 Å²	20	41.4 Å²	41.4	10%	0.103	21%	0.207	C	C	.	.	H	α-helix	trans	-64.8	-44.5	-179.6	-67.9	-68.6	0	0	0	111	M213 A313 L314 F321 F498 L499 F502	M213-I317 HydrophobicContact CE-CD1 4.1Å; A313-I317 WeakPolarHBondContact O-CG1 3.41Å; A313-I317 PolarHBondContact O-N 3.39Å; L314-I317 PolarHBondContact O-N 2.88Å; I317-F321 WeakPolarHBondContact O-CB 3.24Å; I317-F321 PolarHBondContact O-N 3.22Å; I317-F498 HydrophobicContact CD1-CE1 4.45Å; I317-L499 HydrophobicContact CB-CD2 4.37Å; I317-L499 HydrophobicContact CD1-CD2 3.72Å; I317-L499 HydrophobicContact CG2-CD2 3.86Å; I317-F502 HydrophobicContact CB-CE1 4.45Å; I317-F502 HydrophobicContact CD1-CB 3.79Å; I317-F502 HydrophobicContact CD1-CD1 3.47Å; I317-F502 VanDerWaalsContact CD1-CD1 3.47Å; I317-F502 HydrophobicContact CD1-CD2 4.01Å; I317-F502 HydrophobicContact CD1-CE1 4.03Å; I317-F502 HydrophobicContact CD1-CE2 4.49Å; I317-F502 HydrophobicContact CD1-CG 3.45Å; I317-F502 VanDerWaalsContact CD1-CG 3.45Å; I317-F502 HydrophobicContact CD1-CZ 4.49Å; I317-F502 HydrophobicContact CG1-CD1 3.61Å; I317-F502 HydrophobicContact CG1-CD2 4.27Å; I317-F502 HydrophobicContact CG1-CE1 3.6Å; I317-F502 HydrophobicContact CG1-CE2 4.25Å; I317-F502 HydrophobicContact CG1-CG 3.95Å; I317-F502 HydrophobicContact CG1-CZ 3.92Å; I317-F502 HydrophobicContact CG2-CD1 4.36Å; I317-F502 HydrophobicContact CG2-CE1 4.4Å
318	I	93.1	Very high	91.3	Very high	92 Å²	92	39.5 Å²	39.5	47%	0.472	21%	0.205	S	C	.	.	H	α-helix	trans	-64	-44.2	175.5	-66.6	166.1	0	0	0	110.3	L314 F321 L322	L314-I318 WeakPolarHBondContact O-CB 3.33Å; L314-I318 VanDerWaalsContact O-CG1 3.25Å; L314-I318 WeakPolarHBondContact O-CG1 3.45Å; L314-I318 PolarHBondContact O-N 3.42Å; I318-F321 PolarHBondContact O-N 3.48Å; I318-L322 HydrophobicContact CG2-CD1 3.9Å; I318-L322 HydrophobicContact CG2-CG 4.36Å; I318-L322 WeakPolarHBondContact O-CB 3.3Å; I318-L322 VanDerWaalsContact O-CG 3.31Å; I318-L322 WeakPolarHBondContact O-CG 3.31Å; I318-L322 PolarHBondContact O-N 3Å
319	S	92.3	Very high	90.8	Very high	0 Å²	0	40.1 Å²	40.1	0%	0	21%	0.213	C	C	.	.	H	α-helix	trans	-61.9	-48.4	178.6	-56.3	0	0	0	0	111.9	L315 F316 L322 S323 N347 P348 L349	L315-S319 VanDerWaalsContact O-CB 3.29Å; L315-S319 WeakPolarHBondContact O-CB 3.47Å; L315-S319 PolarHBondContact O-N 2.93Å; L315-S319 PolarHBondContact O-OG 3.05Å; F316-S319 PolarHBondContact O-N 3.45Å; S319-L322 PolarHBondContact O-N 3.49Å; S319-S323 WeakPolarHBondContact O-CB 3.23Å; S319-S323 PolarHBondContact O-N 3.13Å; S319-S323 PolarHBondContact O-OG 3.46Å; S319-N347 WeakPolarHBondContact CB-OD1 3.34Å; S319-N347 PolarHBondContact O-ND2 2.98Å; S319-N347 PolarHBondContact OG-OD1 2.91Å; S319-P348 WeakPolarHBondContact OG-CG 3.37Å; S319-L349 WeakPolarHBondContact OG-CG 3.47Å
320	L	92.2	Very high	90.1	Very high	1 Å²	1	42.4 Å²	42.4	1%	0.005	22%	0.224	C	C	.	.	H	α-helix	trans	-62.3	-43.7	176	-76.1	177.8	0	0	0	111.3	F316 S323 N324 L428 F498 L499	F316-L320 WeakPolarHBondContact O-CB 3.25Å; F316-L320 WeakPolarHBondContact O-CG 3.39Å; F316-L320 PolarHBondContact O-N 2.88Å; L320-S323 PolarHBondContact O-N 3.49Å; L320-N324 WeakPolarHBondContact O-CB 3.14Å; L320-N324 PolarHBondContact O-N 2.93Å; L320-N324 PolarHBondContact O-ND2 3.46Å; L320-L428 HydrophobicContact CD1-CD2 4.3Å; L320-L428 HydrophobicContact CD2-CD2 3.65Å; L320-L428 HydrophobicContact CD2-CG 3.84Å; L320-L428 HydrophobicContact CG-CD2 3.5Å; L320-L428 HydrophobicContact CG-CG 4.23Å; L320-F498 HydrophobicContact CD1-CD1 4.05Å; L320-F498 HydrophobicContact CD1-CE1 4.01Å; L320-L499 HydrophobicContact CB-CD2 4.16Å
321	F	93.1	Very high	89.3	Confident	92 Å²	92	41.2 Å²	41.2	40%	0.404	22%	0.22	S	C	.	.	H	α-helix	trans	-60.2	-48.9	178.5	177.4	-100.2	0	0	0	111.3	I317 I318 N324 L325 W496 L499	I317-F321 WeakPolarHBondContact O-CB 3.24Å; I317-F321 PolarHBondContact O-N 3.22Å; I318-F321 PolarHBondContact O-N 3.48Å; F321-N324 PolarHBondContact O-N 2.95Å; F321-L325 HydrophobicContact CE1-CD2 4.33Å; F321-L325 VanDerWaalsContact O-CB 3.3Å; F321-L325 WeakPolarHBondContact O-CB 3.36Å; F321-L325 PolarHBondContact O-N 2.94Å; F321-W496 HydrophobicContact CD2-CH2 4Å; F321-W496 AromaticContact CD2-CZ3 3.95Å; F321-W496 HydrophobicContact CD2-CZ3 3.95Å; F321-W496 AromaticContact CE2-CH2 3.76Å; F321-W496 HydrophobicContact CE2-CH2 3.76Å; F321-W496 AromaticContact CE2-CZ3 3.86Å; F321-W496 HydrophobicContact CE2-CZ3 3.86Å; F321-L499 HydrophobicContact CB-CD1 4.28Å; F321-L499 HydrophobicContact CD2-CD1 4.34Å
322	L	91.2	Very high	88	Confident	41 Å²	41	37.1 Å²	37.1	22%	0.215	20%	0.201	C	C	.	.	H	α-helix	trans	-62.9	-44.1	177.9	-69.5	174.2	0	0	0	112.1	I318 S319 N324 L325 D326	I318-L322 HydrophobicContact CG2-CD1 3.9Å; I318-L322 HydrophobicContact CG2-CG 4.36Å; I318-L322 WeakPolarHBondContact O-CB 3.3Å; I318-L322 VanDerWaalsContact O-CG 3.31Å; I318-L322 WeakPolarHBondContact O-CG 3.31Å; I318-L322 PolarHBondContact O-N 3Å; S319-L322 PolarHBondContact O-N 3.49Å; L322-N324 PolarHBondContact O-N 3.35Å; L322-L325 PolarHBondContact O-N 3.39Å; L322-D326 WeakPolarHBondContact O-CB 3.46Å; L322-D326 PolarHBondContact O-N 3.49Å
323	S	88.4	Confident	87	Confident	6 Å²	6	37 Å²	37	4%	0.042	21%	0.206	C	C	.	.	H	α-helix	trans	-59.6	-44.7	175.3	-75.7	0	0	0	0	112.6	S319 L320 D326 K327 N347 S427	S319-S323 WeakPolarHBondContact O-CB 3.23Å; S319-S323 PolarHBondContact O-N 3.13Å; S319-S323 PolarHBondContact O-OG 3.46Å; L320-S323 PolarHBondContact O-N 3.49Å; S323-D326 PolarHBondContact O-N 2.86Å; S323-K327 WeakPolarHBondContact O-CG 3.29Å; S323-K327 PolarHBondContact O-N 2.99Å; S323-N347 PolarHBondContact OG-ND2 2.98Å; S323-S427 WeakPolarHBondContact CB-O 3.35Å; S323-S427 PolarHBondContact OG-O 3.32Å
324	N	89.6	Confident	86.1	Confident	0 Å²	0	41.4 Å²	41.4	0%	0	23%	0.228	C	C	.	.	H	α-helix	trans	-74.2	-29.6	-179	-70.4	-63.5	0	0	0	112.2	L320 F321 L322 A328 Y492 N495 W496	L320-N324 WeakPolarHBondContact O-CB 3.14Å; L320-N324 PolarHBondContact O-N 2.93Å; L320-N324 PolarHBondContact O-ND2 3.46Å; F321-N324 PolarHBondContact O-N 2.95Å; L322-N324 PolarHBondContact O-N 3.35Å; N324-A328 WeakPolarHBondContact O-CB 3.39Å; N324-A328 PolarHBondContact O-N 2.77Å; N324-Y492 HydrophobicContact CB-CE2 4.07Å; N324-N495 VanDerWaalsContact ND2-CB 3.35Å; N324-N495 WeakPolarHBondContact ND2-CB 3.07Å; N324-N495 PolarHBondContact OD1-ND2 3.45Å; N324-N495 VanDerWaalsContact OD1-ND2 3.12Å; N324-W496 HydrophobicContact CB-CZ2 4.22Å
325	L	88.8	Confident	84.9	Confident	54 Å²	54	42.1 Å²	42.1	28%	0.283	23%	0.232	S	C	.	.	H	α-helix	trans	-66.2	-42.8	170.8	-175.9	65.2	0	0	0	110.9	F321 L322 K327 A328 L329 L345	F321-L325 HydrophobicContact CE1-CD2 4.33Å; F321-L325 VanDerWaalsContact O-CB 3.3Å; F321-L325 WeakPolarHBondContact O-CB 3.36Å; F321-L325 PolarHBondContact O-N 2.94Å; L322-L325 PolarHBondContact O-N 3.39Å; L325-K327 VanDerWaalsContact C-N 3.33Å; L325-K327 PolarHBondContact O-N 2.62Å; L325-A328 WeakPolarHBondContact O-CB 3.31Å; L325-A328 PolarHBondContact O-N 2.76Å; L325-A328 VanDerWaalsContact O-N 3.1Å; L325-L329 HydrophobicContact CD1-CD1 4.17Å; L325-L329 HydrophobicContact CD1-CG 4.4Å; L325-L329 HydrophobicContact CG-CD1 4.02Å; L325-L329 WeakPolarHBondContact O-CG 3.12Å; L325-L329 PolarHBondContact O-N 2.91Å; L325-L345 HydrophobicContact CD2-CD1 4.26Å; L325-L345 HydrophobicContact CG-CD1 4.23Å
326	D	85.9	Confident	83.7	Confident	3 Å²	3	39.2 Å²	39.2	2%	0.016	22%	0.217	C	C	.	.	H	α-helix	trans	-61.4	-43.2	175.4	-158.5	32	0	0	0	111.3	L322 S323 A328 L329 H330 I340 T343 L345	L322-D326 WeakPolarHBondContact O-CB 3.46Å; L322-D326 PolarHBondContact O-N 3.49Å; S323-D326 PolarHBondContact O-N 2.86Å; D326-A328 VanDerWaalsContact C-N 3.31Å; D326-A328 PolarHBondContact O-N 2.9Å; D326-L329 PolarHBondContact O-N 3.28Å; D326-H330 PolarHBondContact O-N 3.32Å; D326-H330 IonicContact OD1-CE1 3.89Å; D326-H330 IonicContact OD1-CG 2.58Å; D326-H330 IonicContact OD1-ND1 2.62Å; D326-H330 PolarHBondContact OD1-ND1 2.92Å; D326-I340 HydrophobicContact CB-CD1 4.3Å; D326-T343 WeakPolarHBondContact OD2-CA 3.45Å; D326-L345 HydrophobicContact CB-CB 4.17Å; D326-L345 HydrophobicContact CB-CD1 3.92Å; D326-L345 HydrophobicContact CB-CG 4.5Å
327	K	84.2	Confident	82.7	Confident	10 Å²	10	39.1 Å²	39.1	4%	0.043	22%	0.217	C	C	.	.	H	α-helix	trans	-58.7	-41	171.8	-73.9	-176.8	179.6	-176.4	0	112.1	S323 L325 L329 S331 F338 I340 Y492	S323-K327 WeakPolarHBondContact O-CG 3.29Å; S323-K327 PolarHBondContact O-N 2.99Å; L325-K327 VanDerWaalsContact C-N 3.33Å; L325-K327 PolarHBondContact O-N 2.62Å; K327-L329 VanDerWaalsContact C-N 3.33Å; K327-L329 PolarHBondContact O-N 3.39Å; K327-S331 WeakPolarHBondContact O-CB 3.47Å; K327-S331 PolarHBondContact O-N 2.9Å; K327-S331 PolarHBondContact O-OG 3.2Å; K327-F338 HydrophobicContact CB-CB 4.39Å; K327-F338 HydrophobicContact CD-CB 4.49Å; K327-I340 HydrophobicContact CB-CD1 4.11Å; K327-I340 HydrophobicContact CB-CG1 4.33Å; K327-I340 HydrophobicContact CD-CD1 4.26Å; K327-I340 HydrophobicContact CG-CD1 3.17Å; K327-I340 HydrophobicContact CG-CG1 3.61Å; K327-Y492 HydrophobicContact CB-CD2 4.08Å; K327-Y492 HydrophobicContact CB-CE2 3.71Å; K327-Y492 HydrophobicContact CD-CD2 3.95Å; K327-Y492 HydrophobicContact CD-CE2 4.41Å
328	A	85.3	Confident	81.8	Confident	50 Å²	50	39.1 Å²	39.1	41%	0.413	22%	0.217	S	C	.	.	H	α-helix	trans	-66.6	-36.1	-178.9	0	0	0	0	0	112.5	N324 L325 D326 Y492	N324-A328 WeakPolarHBondContact O-CB 3.39Å; N324-A328 PolarHBondContact O-N 2.77Å; L325-A328 WeakPolarHBondContact O-CB 3.31Å; L325-A328 PolarHBondContact O-N 2.76Å; L325-A328 VanDerWaalsContact O-N 3.1Å; D326-A328 VanDerWaalsContact C-N 3.31Å; D326-A328 PolarHBondContact O-N 2.9Å; A328-Y492 WeakPolarHBondContact CB-OH 3.47Å
329	L	82.9	Confident	80.7	Confident	113 Å²	113	35.3 Å²	35.3	59%	0.592	20%	0.197	S	C	*	.	H	α-helix	trans	-89.8	-35.2	-173.3	-65.7	173.6	0	0	0	113.3	L325 D326 K327 L345	L325-L329 HydrophobicContact CD1-CD1 4.17Å; L325-L329 HydrophobicContact CD1-CG 4.4Å; L325-L329 HydrophobicContact CG-CD1 4.02Å; L325-L329 WeakPolarHBondContact O-CG 3.12Å; L325-L329 PolarHBondContact O-N 2.91Å; D326-L329 PolarHBondContact O-N 3.28Å; K327-L329 VanDerWaalsContact C-N 3.33Å; K327-L329 PolarHBondContact O-N 3.39Å; L329-L345 HydrophobicContact CD1-CD1 4.44Å
330	H	79.4	Confident	79.6	Confident	86 Å²	86	35.9 Å²	35.9	40%	0.398	20%	0.2	S	C	.	.	H	α-helix	trans	-123	1.9	-166.3	-56.2	114.6	0	0	0	114.9	D326	D326-H330 PolarHBondContact O-N 3.32Å; D326-H330 IonicContact OD1-CE1 3.89Å; D326-H330 IonicContact OD1-CG 2.58Å; D326-H330 IonicContact OD1-ND1 2.62Å; D326-H330 PolarHBondContact OD1-ND1 2.92Å
331	S	75.6	Confident	78	Confident	24 Å²	24	36.3 Å²	36.3	17%	0.168	20%	0.202	C	C	.	.	S	Bend	trans	-81.1	161.5	177.7	72.1	0	0	0	0	113	K327 G333 F338 I339	K327-S331 WeakPolarHBondContact O-CB 3.47Å; K327-S331 PolarHBondContact O-N 2.9Å; K327-S331 PolarHBondContact O-OG 3.2Å; S331-G333 PolarHBondContact O-N 2.83Å; S331-G333 PolarHBondContact OG-N 2.88Å; S331-F338 VanDerWaalsContact OG-CD1 3.3Å; S331-F338 WeakPolarHBondContact OG-CD1 3.19Å; S331-I339 WeakPolarHBondContact CB-O 2.9Å
332	A	67.5	Low	76.5	Confident	21 Å²	21	33.1 Å²	33.1	17%	0.174	20%	0.195	C	C	.	.			trans	-68.2	2.3	174.9	0	0	0	0	0	114.8	W171 S336 F341	W171-A332 HydrophobicContact CZ2-CB 4.4Å; A332-S336 VanDerWaalsContact CB-OG 3.25Å; A332-S336 WeakPolarHBondContact CB-OG 3.28Å; A332-F341 HydrophobicContact CB-CE2 3.87Å; A332-F341 HydrophobicContact CB-CZ 4.5Å
333	G	71.3	Confident	75.2	Confident	25 Å²	25	33.6 Å²	33.6	26%	0.258	20%	0.2	S	C	.	.			trans	104.6	-168.6	174.9	0	0	0	0	0	114.9	S331 S336 F338	S331-G333 PolarHBondContact O-N 2.83Å; S331-G333 PolarHBondContact OG-N 2.88Å; G333-S336 PolarHBondContact O-OG 3.5Å; G333-F338 PolarHBondContact O-N 2.98Å; G333-F338 VanDerWaalsContact O-N 3.14Å
334	I	74.7	Confident	74.1	Confident	93 Å²	93	39.1 Å²	39.1	48%	0.477	23%	0.229	S	C	.	.	G	3₁₀ helix	trans	-65.7	-39.4	-178.8	-65.5	164.5	0	0	0	111.1	S336 G337 F338 W485	I334-S336 PolarHBondContact O-N 3.05Å; I334-S336 VanDerWaalsContact O-N 3.17Å; I334-G337 PolarHBondContact O-N 2.71Å; I334-F338 HydrophobicContact CB-CE2 4.25Å; I334-F338 HydrophobicContact CB-CZ 4.33Å; I334-F338 HydrophobicContact CD1-CZ 4.47Å; I334-F338 HydrophobicContact CG1-CE1 4.33Å; I334-F338 HydrophobicContact CG1-CE2 3.68Å; I334-F338 HydrophobicContact CG1-CZ 3.38Å; I334-W485 WeakPolarHBondContact O-CZ3 3.43Å
335	D	68.4	Low	73.3	Confident	87 Å²	87	42 Å²	42	47%	0.465	24%	0.244	S	C	.	.	G	3₁₀ helix	trans	-67.4	-15	-174.4	-63.8	-29.1	0	0	0	114.1	P163	P163-D335 HydrophobicContact CG-CB 3.74Å
336	S	67.4	Low	72.7	Confident	0 Å²	0	43.2 Å²	43.2	0%	0	26%	0.256	C	S	.	.	G	3₁₀ helix	trans	-108.3	5.9	174.6	61.9	0	0	0	0	112.9	A332 G333 I334 I339	A332-S336 VanDerWaalsContact CB-OG 3.25Å; A332-S336 WeakPolarHBondContact CB-OG 3.28Å; G333-S336 PolarHBondContact O-OG 3.5Å; I334-S336 PolarHBondContact O-N 3.05Å; I334-S336 VanDerWaalsContact O-N 3.17Å; S336-I339 WeakPolarHBondContact O-CD1 3.16Å; S336-I339 WeakPolarHBondContact O-CG1 3.41Å
337	G	70.6	Confident	72.6	Confident	4 Å²	4	43.4 Å²	43.4	4%	0.041	26%	0.257	C	S	.	.	T	Hydrogen-bonded Turn	trans	73.1	23.7	-179.8	0	0	0	0	0	114.7	I334 I339 W485 S488	I334-G337 PolarHBondContact O-N 2.71Å; G337-I339 VanDerWaalsContact C-N 3.31Å; G337-I339 PolarHBondContact O-N 3.47Å; G337-W485 VanDerWaalsContact CA-O 3.28Å; G337-W485 WeakPolarHBondContact CA-O 3.43Å; G337-S488 WeakPolarHBondContact O-CB 3.48Å
338	F	76.4	Confident	72.8	Confident	20 Å²	20	45 Å²	45	9%	0.088	27%	0.269	C	S	.	.	T	Hydrogen-bonded Turn	trans	57.1	37.5	-178.2	-61.4	-90.3	0	0	0	114.3	K327 S331 G333 I334 A489 Y492 F493	K327-F338 HydrophobicContact CB-CB 4.39Å; K327-F338 HydrophobicContact CD-CB 4.49Å; S331-F338 VanDerWaalsContact OG-CD1 3.3Å; S331-F338 WeakPolarHBondContact OG-CD1 3.19Å; G333-F338 PolarHBondContact O-N 2.98Å; G333-F338 VanDerWaalsContact O-N 3.14Å; I334-F338 HydrophobicContact CB-CE2 4.25Å; I334-F338 HydrophobicContact CB-CZ 4.33Å; I334-F338 HydrophobicContact CD1-CZ 4.47Å; I334-F338 HydrophobicContact CG1-CE1 4.33Å; I334-F338 HydrophobicContact CG1-CE2 3.68Å; I334-F338 HydrophobicContact CG1-CZ 3.38Å; F338-A489 HydrophobicContact CD2-CB 4.43Å; F338-Y492 HydrophobicContact CB-CD2 4.27Å; F338-Y492 HydrophobicContact CB-CG 4.3Å; F338-Y492 HydrophobicContact CD1-CD1 4.29Å; F338-Y492 HydrophobicContact CD1-CD2 4.48Å; F338-Y492 HydrophobicContact CD1-CE1 4.2Å; F338-Y492 HydrophobicContact CD1-CE2 4.37Å; F338-Y492 HydrophobicContact CD1-CG 4.42Å; F338-Y492 AromaticContact CD2-CD1 3.7Å; F338-Y492 HydrophobicContact CD2-CD1 3.7Å; F338-Y492 HydrophobicContact CD2-CD2 4.49Å; F338-Y492 HydrophobicContact CD2-CE1 4.35Å; F338-Y492 AromaticContact CD2-CG 3.78Å; F338-Y492 HydrophobicContact CD2-CG 3.78Å; F338-Y492 HydrophobicContact CE1-CD1 4.18Å; F338-Y492 AromaticContact CE1-CE1 3.85Å; F338-Y492 HydrophobicContact CE1-CE1 3.85Å; F338-Y492 AromaticContact CE2-CD1 3.54Å; F338-Y492 HydrophobicContact CE2-CD1 3.54Å; F338-Y492 AromaticContact CE2-CE1 3.99Å; F338-Y492 HydrophobicContact CE2-CE1 3.99Å; F338-Y492 HydrophobicContact CE2-CG 4.12Å; F338-Y492 HydrophobicContact CG-CD1 4.07Å; F338-Y492 HydrophobicContact CG-CD2 4.2Å; F338-Y492 HydrophobicContact CG-CE1 4.44Å; F338-Y492 AromaticContact CG-CG 3.94Å; F338-Y492 HydrophobicContact CG-CG 3.94Å; F338-Y492 AromaticContact CZ-CD1 3.78Å; F338-Y492 HydrophobicContact CZ-CD1 3.78Å; F338-Y492 AromaticContact CZ-CE1 3.72Å; F338-Y492 HydrophobicContact CZ-CE1 3.72Å; F338-F493 HydrophobicContact CE2-CE2 4.24Å; F338-F493 HydrophobicContact CE2-CZ 4.3Å; F338-F493 HydrophobicContact CZ-CZ 4.38Å
339	I	70.4	Confident	72.7	Confident	11 Å²	11	42.8 Å²	42.8	6%	0.056	25%	0.25	C	S	.	.			trans	-70	133.7	172	-60.9	168.9	0	0	0	108.9	F178 S331 S336 G337 F341	F178-I339 HydrophobicContact CE2-CD1 3.96Å; F178-I339 HydrophobicContact CZ-CD1 3.87Å; S331-I339 WeakPolarHBondContact CB-O 2.9Å; S336-I339 WeakPolarHBondContact O-CD1 3.16Å; S336-I339 WeakPolarHBondContact O-CG1 3.41Å; G337-I339 VanDerWaalsContact C-N 3.31Å; G337-I339 PolarHBondContact O-N 3.47Å; I339-F341 HydrophobicContact CG2-CE1 4.27Å; I339-F341 HydrophobicContact CG2-CZ 4.32Å
340	I	68.6	Low	72.7	Confident	13 Å²	13	38.4 Å²	38.4	7%	0.067	23%	0.228	C	C	.	.			trans	-100.2	131.2	177.2	-66.6	162.4	0	0	0	109	D326 K327 G342	D326-I340 HydrophobicContact CB-CD1 4.3Å; K327-I340 HydrophobicContact CB-CD1 4.11Å; K327-I340 HydrophobicContact CB-CG1 4.33Å; K327-I340 HydrophobicContact CD-CD1 4.26Å; K327-I340 HydrophobicContact CG-CD1 3.17Å; K327-I340 HydrophobicContact CG-CG1 3.61Å; I340-G342 VanDerWaalsContact CG2-C 3.46Å; I340-G342 WeakPolarHBondContact CG2-O 3.38Å
341	F	59.2	Low	73	Confident	10 Å²	10	39.4 Å²	39.4	4%	0.044	23%	0.234	C	C	.	.	S	Bend	trans	-88	-23	176.9	-57.2	-73.9	0	0	0	113.8	V174 A332 I339 A465	V174-F341 HydrophobicContact CG2-CE1 3.34Å; V174-F341 HydrophobicContact CG2-CE2 4.28Å; V174-F341 HydrophobicContact CG2-CZ 3.1Å; A332-F341 HydrophobicContact CB-CE2 3.87Å; A332-F341 HydrophobicContact CB-CZ 4.5Å; I339-F341 HydrophobicContact CG2-CE1 4.27Å; I339-F341 HydrophobicContact CG2-CZ 4.32Å; F341-A465 VanDerWaalsContact CA-CB 3.47Å; F341-A465 HydrophobicContact CB-CB 3.87Å; F341-A465 HydrophobicContact CD1-CB 3.75Å; F341-A465 HydrophobicContact CG-CB 4.3Å; F341-A465 WeakPolarHBondContact O-CA 3.35Å; F341-A465 WeakPolarHBondContact O-CB 3.45Å; F341-A465 PolarHBondContact O-N 2.78Å
342	G	61.2	Low	73.4	Confident	24 Å²	24	41.4 Å²	41.4	25%	0.247	24%	0.242	C	C	.	.	S	Bend	trans	-158.8	141.4	173.1	0	0	0	0	0	111.7	I340	I340-G342 VanDerWaalsContact CG2-C 3.46Å; I340-G342 WeakPolarHBondContact CG2-O 3.38Å
343	T	63.3	Low	74.2	Confident	52 Å²	52	40.6 Å²	40.6	32%	0.319	24%	0.235	S	C	.	.			trans	-85.3	119.8	177.9	50.3	0	0	0	0	110.8	D326 Q431	D326-T343 WeakPolarHBondContact OD2-CA 3.45Å; T343-Q431 HydrophobicContact CG2-CG 3.52Å
344	N	65.7	Low	74.6	Confident	122 Å²	122	40.2 Å²	40.2	65%	0.652	23%	0.228	S	C	*	.			trans	-97.8	-23.7	171.9	-76.7	-24.9	0	0	0	112.3
345	L	73.6	Confident	75.1	Confident	60 Å²	60	41.4 Å²	41.4	31%	0.314	24%	0.235	S	C	.	.	S	Bend	trans	-95.4	127.2	178	-73.3	166.4	0	0	0	111.9	L325 D326 L329 N347	L325-L345 HydrophobicContact CD2-CD1 4.26Å; L325-L345 HydrophobicContact CG-CD1 4.23Å; D326-L345 HydrophobicContact CB-CB 4.17Å; D326-L345 HydrophobicContact CB-CD1 3.92Å; D326-L345 HydrophobicContact CB-CG 4.5Å; L329-L345 HydrophobicContact CD1-CD1 4.44Å; L345-N347 PolarHBondContact O-N 2.84Å
346	S	75.5	Confident	75.7	Confident	79 Å²	79	39.3 Å²	39.3	55%	0.552	22%	0.223	S	C	*	.			trans	-69.8	95.1	179.1	-65.4	0	0	0	0	112.1	M351	S346-M351 WeakPolarHBondContact OG-CE 3.49Å
347	N	84.4	Confident	76.3	Confident	7 Å²	7	40.5 Å²	40.5	4%	0.037	23%	0.229	C	C	.	.			trans	-79.7	127.3	170.2	174	-22.6	0	0	0	110.4	S319 S323 L345 L349 N350 M351 L428	S319-N347 WeakPolarHBondContact CB-OD1 3.34Å; S319-N347 PolarHBondContact O-ND2 2.98Å; S319-N347 PolarHBondContact OG-OD1 2.91Å; S323-N347 PolarHBondContact OG-ND2 2.98Å; L345-N347 PolarHBondContact O-N 2.84Å; N347-L349 PolarHBondContact O-N 3.38Å; N347-L349 PolarHBondContact OD1-N 3.19Å; N347-N350 HydrophobicContact CB-CB 3.87Å; N347-N350 PolarHBondContact O-N 3.01Å; N347-N350 VanDerWaalsContact O-N 3.16Å; N347-N350 PolarHBondContact OD1-N 3.28Å; N347-M351 PolarHBondContact O-N 3.36Å; N347-L428 PolarHBondContact ND2-O 3.21Å
348	P	87.4	Confident	76.6	Confident	45 Å²	45	44.8 Å²	44.8	29%	0.292	25%	0.254	S	S	.	.	H	α-helix	trans	-62.4	-37.6	-174.9	25.8	-34.9	0	0	0	113.4	L315 S319 M351 L352	L315-P348 HydrophobicContact CD1-CB 4.06Å; L315-P348 HydrophobicContact CD1-CG 3.96Å; S319-P348 WeakPolarHBondContact OG-CG 3.37Å; P348-M351 PolarHBondContact O-N 3.22Å; P348-L352 VanDerWaalsContact O-CB 3.27Å; P348-L352 WeakPolarHBondContact O-CB 3.43Å; P348-L352 PolarHBondContact O-N 3.3Å
349	L	83.7	Confident	76.7	Confident	3 Å²	3	47.9 Å²	47.9	2%	0.016	27%	0.274	C	S	.	.	H	α-helix	trans	-69.9	-37.3	176.2	-79.5	175.6	0	0	0	112.2	L315 F316 S319 N347 M351 L352 L353 L428	L315-L349 HydrophobicContact CD2-CD2 3.96Å; L315-L349 HydrophobicContact CD2-CG 4.43Å; L315-L349 HydrophobicContact CG-CD2 4.43Å; L315-L349 HydrophobicContact CG-CG 4.37Å; F316-L349 HydrophobicContact CD1-CD1 3.6Å; F316-L349 HydrophobicContact CE1-CD1 3.77Å; S319-L349 WeakPolarHBondContact OG-CG 3.47Å; N347-L349 PolarHBondContact O-N 3.38Å; N347-L349 PolarHBondContact OD1-N 3.19Å; L349-M351 PolarHBondContact O-N 3.42Å; L349-L352 HydrophobicContact CD2-CD2 4.38Å; L349-L352 PolarHBondContact O-N 3.06Å; L349-L353 WeakPolarHBondContact O-CB 3.08Å; L349-L353 WeakPolarHBondContact O-CG 3.42Å; L349-L353 PolarHBondContact O-N 3.27Å; L349-L428 HydrophobicContact CD1-CB 4.18Å; L349-L428 HydrophobicContact CD1-CD1 4.49Å; L349-L428 HydrophobicContact CD1-CD2 3.89Å; L349-L428 HydrophobicContact CD1-CG 4.44Å
350	N	83.6	Confident	76.5	Confident	21 Å²	21	53.6 Å²	53.6	11%	0.112	30%	0.299	C	S	.	.	H	α-helix	trans	-67.8	-22.2	176.8	-159.6	60.7	0	0	0	112.4	N347 P354 A429 Q431 Y432	N347-N350 HydrophobicContact CB-CB 3.87Å; N347-N350 PolarHBondContact O-N 3.01Å; N347-N350 VanDerWaalsContact O-N 3.16Å; N347-N350 PolarHBondContact OD1-N 3.28Å; N350-P354 WeakPolarHBondContact O-CD 3.24Å; N350-P354 WeakPolarHBondContact O-CG 3.35Å; N350-A429 HydrophobicContact CB-CB 4.38Å; N350-Q431 PolarHBondContact OD1-N 3.02Å; N350-Y432 PolarHBondContact OD1-N 3.46Å
351	M	84.2	Confident	76.7	Confident	107 Å²	107	55.5 Å²	55.5	53%	0.527	31%	0.312	S	S	.	.	H	α-helix	trans	-84.3	-39	169.9	-71.4	-174.6	161.7	0	0	113	S346 N347 P348 L349	S346-M351 WeakPolarHBondContact OG-CE 3.49Å; N347-M351 PolarHBondContact O-N 3.36Å; P348-M351 PolarHBondContact O-N 3.22Å; L349-M351 PolarHBondContact O-N 3.42Å
352	L	85.3	Confident	77.7	Confident	65 Å²	65	58.5 Å²	58.5	34%	0.34	33%	0.328	S	S	.	.	H	α-helix	trans	-71.3	-44.9	-175	179.1	60.3	0	0	0	112.8	P348 L349 L355 L356 L366	P348-L352 VanDerWaalsContact O-CB 3.27Å; P348-L352 WeakPolarHBondContact O-CB 3.43Å; P348-L352 PolarHBondContact O-N 3.3Å; L349-L352 HydrophobicContact CD2-CD2 4.38Å; L349-L352 PolarHBondContact O-N 3.06Å; L352-L355 WeakPolarHBondContact O-CB 3.32Å; L352-L355 PolarHBondContact O-N 3.18Å; L352-L356 HydrophobicContact CD1-CD1 3.76Å; L352-L356 HydrophobicContact CD1-CG 4.26Å; L352-L356 HydrophobicContact CD2-CD1 4.34Å; L352-L356 HydrophobicContact CG-CD1 3.6Å; L352-L356 WeakPolarHBondContact O-CD1 3.13Å; L352-L356 PolarHBondContact O-N 3.4Å; L352-L366 HydrophobicContact CD2-CD2 4.15Å; L352-L366 HydrophobicContact CG-CD2 4.42Å
353	L	83.9	Confident	78.8	Confident	4 Å²	4	57.6 Å²	57.6	2%	0.021	32%	0.318	C	S	.	.	H	α-helix	trans	-62.1	-47.4	-175.1	-75.8	162.3	0	0	0	113.3	L349 L355 L356 Q357 L366 I367 A429 Y432	L349-L353 WeakPolarHBondContact O-CB 3.08Å; L349-L353 WeakPolarHBondContact O-CG 3.42Å; L349-L353 PolarHBondContact O-N 3.27Å; L353-L355 VanDerWaalsContact C-N 3.26Å; L353-L355 PolarHBondContact O-N 3.16Å; L353-L356 PolarHBondContact O-N 2.97Å; L353-Q357 PolarHBondContact O-N 2.98Å; L353-Q357 VanDerWaalsContact O-N 3.11Å; L353-L366 HydrophobicContact CD2-CB 4.49Å; L353-L366 HydrophobicContact CD2-CD2 3.8Å; L353-L366 HydrophobicContact CD2-CG 4.28Å; L353-L366 HydrophobicContact CG-CD2 4.48Å; L353-I367 HydrophobicContact CD2-CD1 4.48Å; L353-I367 HydrophobicContact CD2-CG1 3.95Å; L353-A429 HydrophobicContact CD1-CB 3.64Å; L353-Y432 HydrophobicContact CB-CD1 3.76Å; L353-Y432 HydrophobicContact CB-CD2 3.72Å; L353-Y432 HydrophobicContact CB-CE1 3.95Å; L353-Y432 HydrophobicContact CB-CE2 3.86Å; L353-Y432 HydrophobicContact CB-CG 3.65Å; L353-Y432 HydrophobicContact CD1-CD1 3.77Å; L353-Y432 HydrophobicContact CD1-CE1 4.2Å; L353-Y432 HydrophobicContact CD1-CG 4.29Å; L353-Y432 HydrophobicContact CD2-CE1 4.22Å; L353-Y432 HydrophobicContact CG-CD1 4.25Å; L353-Y432 HydrophobicContact CG-CE1 4.36Å
354	P	80.4	Confident	79.7	Confident	18 Å²	18	57.4 Å²	57.4	12%	0.117	31%	0.312	C	S	.	.	H	α-helix	trans	-62.4	-31.6	174	-19.5	28.7	0	0	0	113.5	N350 Q357 Y432	N350-P354 WeakPolarHBondContact O-CD 3.24Å; N350-P354 WeakPolarHBondContact O-CG 3.35Å; P354-Q357 PolarHBondContact O-N 2.88Å; P354-Y432 HydrophobicContact CB-CD2 4.4Å; P354-Y432 HydrophobicContact CG-CD2 3.84Å
355	L	83.5	Confident	80.6	Confident	118 Å²	118	55.4 Å²	55.4	62%	0.618	30%	0.3	S	S	*	.	H	α-helix	trans	-68	-44.7	177.6	-176.5	69.8	0	0	0	110.8	L352 L353 Q357 T358	L352-L355 WeakPolarHBondContact O-CB 3.32Å; L352-L355 PolarHBondContact O-N 3.18Å; L353-L355 VanDerWaalsContact C-N 3.26Å; L353-L355 PolarHBondContact O-N 3.16Å; L355-Q357 PolarHBondContact O-N 3.44Å; L355-T358 WeakPolarHBondContact O-CB 3.17Å; L355-T358 WeakPolarHBondContact O-CG2 3.42Å; L355-T358 PolarHBondContact O-N 3.31Å; L355-T358 PolarHBondContact O-OG1 2.88Å
356	L	82.1	Confident	81.2	Confident	42 Å²	42	54.4 Å²	54.4	22%	0.22	30%	0.295	C	S	.	.	H	α-helix	trans	-62.8	-32.5	176.3	-76.3	149.3	0	0	0	112.3	L352 L353 T358 V359 L362 D363 L366	L352-L356 HydrophobicContact CD1-CD1 3.76Å; L352-L356 HydrophobicContact CD1-CG 4.26Å; L352-L356 HydrophobicContact CD2-CD1 4.34Å; L352-L356 HydrophobicContact CG-CD1 3.6Å; L352-L356 WeakPolarHBondContact O-CD1 3.13Å; L352-L356 PolarHBondContact O-N 3.4Å; L353-L356 PolarHBondContact O-N 2.97Å; L356-T358 PolarHBondContact O-N 2.85Å; L356-V359 CarbonylContact O-C 3.56Å; L356-V359 PolarHBondContact O-N 3.36Å; L356-V359 VanDerWaalsContact O-O 3.12Å; L356-L362 HydrophobicContact CB-CB 4.21Å; L356-L362 HydrophobicContact CD2-CB 3.76Å; L356-L362 HydrophobicContact CD2-CD1 4.1Å; L356-D363 HydrophobicContact CB-CB 4.17Å; L356-L366 HydrophobicContact CD1-CB 4.45Å; L356-L366 HydrophobicContact CD1-CD2 3.3Å; L356-L366 HydrophobicContact CD1-CG 4.45Å
357	Q	79	Confident	81.8	Confident	26 Å²	26	50.7 Å²	50.7	12%	0.121	27%	0.269	C	S	.	.	H	α-helix	trans	-62.8	-21.7	177.7	-172.2	167.7	4.2	0	0	113.2	S69 L353 P354 L355 V359 D363 Y432 S437	S69-Q357 PolarHBondContact OG-NE2 3.47Å; L353-Q357 PolarHBondContact O-N 2.98Å; L353-Q357 VanDerWaalsContact O-N 3.11Å; P354-Q357 PolarHBondContact O-N 2.88Å; L355-Q357 PolarHBondContact O-N 3.44Å; Q357-V359 PolarHBondContact O-N 2.91Å; Q357-D363 HydrophobicContact CB-CB 4.12Å; Q357-D363 WeakPolarHBondContact CB-OD2 3.49Å; Q357-D363 WeakPolarHBondContact CG-OD2 3.36Å; Q357-Y432 HydrophobicContact CB-CE2 4.48Å; Q357-S437 VanDerWaalsContact CD-OG 3.22Å; Q357-S437 PolarHBondContact NE2-OG 3.11Å; Q357-S437 VanDerWaalsContact NE2-OG 3.09Å; Q357-S437 PolarHBondContact OE1-OG 3.47Å
358	T	76.6	Confident	81.9	Confident	93 Å²	93	52.2 Å²	52.2	57%	0.571	28%	0.278	S	S	*	.	T	Hydrogen-bonded Turn	trans	-61.9	-25.9	173.4	65	0	0	0	0	112.8	L355 L356	L355-T358 WeakPolarHBondContact O-CB 3.17Å; L355-T358 WeakPolarHBondContact O-CG2 3.42Å; L355-T358 PolarHBondContact O-N 3.31Å; L355-T358 PolarHBondContact O-OG1 2.88Å; L356-T358 PolarHBondContact O-N 2.85Å
359	V	79.2	Confident	82	Confident	85 Å²	85	54.7 Å²	54.7	52%	0.515	29%	0.288	S	S	.	.	S	Bend	trans	-114.7	88	176.5	-176.1	0	0	0	0	108.2	L356 Q357 L362	L356-V359 CarbonylContact O-C 3.56Å; L356-V359 PolarHBondContact O-N 3.36Å; L356-V359 VanDerWaalsContact O-O 3.12Å; Q357-V359 PolarHBondContact O-N 2.91Å; V359-L362 HydrophobicContact CB-CD1 3.82Å; V359-L362 HydrophobicContact CB-CG 4.33Å; V359-L362 HydrophobicContact CG1-CD1 3.82Å; V359-L362 HydrophobicContact CG1-CG 4.18Å; V359-L362 WeakPolarHBondContact O-CB 3.2Å; V359-L362 WeakPolarHBondContact O-CG 3.26Å; V359-L362 PolarHBondContact O-N 3.38Å
360	F	65.8	Low	82.3	Confident	132 Å²	132	55 Å²	55	58%	0.579	29%	0.289	S	S	*	.	T	Hydrogen-bonded Turn	trans	-61.7	134.3	177.5	-178.5	-99.1	0	0	0	111	F66	F66-F360 HydrophobicContact CD2-CD2 4.05Å; F66-F360 AromaticContact CD2-CE2 3.58Å; F66-F360 HydrophobicContact CD2-CE2 3.58Å; F66-F360 AromaticContact CE2-CD2 3.65Å; F66-F360 HydrophobicContact CE2-CD2 3.65Å; F66-F360 AromaticContact CE2-CE2 3.23Å; F66-F360 HydrophobicContact CE2-CE2 3.23Å; F66-F360 HydrophobicContact CE2-CZ 4.04Å; F66-F360 HydrophobicContact CG-CE2 4.41Å; F66-F360 AromaticContact CZ-CE2 3.84Å; F66-F360 HydrophobicContact CZ-CE2 3.84Å; F66-F360 HydrophobicContact CZ-CZ 4.2Å
361	P	74.1	Confident	82.7	Confident	52 Å²	52	54.3 Å²	54.3	34%	0.338	29%	0.286	S	S	.	.	T	Hydrogen-bonded Turn	cis	-109.9	44.1	3.8	40.9	-33.5	0	0	0	114	D363 Y364 I365	P361-D363 PolarHBondContact O-N 3.11Å; P361-Y364 PolarHBondContact O-N 3.45Å; P361-I365 HydrophobicContact CG-CD1 4.25Å; P361-I365 WeakPolarHBondContact O-CG1 3.42Å; P361-I365 PolarHBondContact O-N 3.33Å
362	L	80.5	Confident	83	Confident	73 Å²	73	51.4 Å²	51.4	38%	0.382	27%	0.272	S	S	.	.	H	α-helix	trans	-66.9	-33.4	-170.8	-68.8	-177.8	0	0	0	114.3	L356 V359 I365 L366	L356-L362 HydrophobicContact CB-CB 4.21Å; L356-L362 HydrophobicContact CD2-CB 3.76Å; L356-L362 HydrophobicContact CD2-CD1 4.1Å; V359-L362 HydrophobicContact CB-CD1 3.82Å; V359-L362 HydrophobicContact CB-CG 4.33Å; V359-L362 HydrophobicContact CG1-CD1 3.82Å; V359-L362 HydrophobicContact CG1-CG 4.18Å; V359-L362 WeakPolarHBondContact O-CB 3.2Å; V359-L362 WeakPolarHBondContact O-CG 3.26Å; V359-L362 PolarHBondContact O-N 3.38Å; L362-I365 PolarHBondContact O-N 3.11Å; L362-L366 PolarHBondContact O-N 2.94Å
363	D	82.8	Confident	83.4	Confident	5 Å²	5	48.8 Å²	48.8	3%	0.027	26%	0.257	C	S	.	.	H	α-helix	trans	-66.3	-42.1	177.3	62.9	-25.6	0	0	0	112.2	L356 Q357 P361 I365 L366 I367 Y432	L356-D363 HydrophobicContact CB-CB 4.17Å; Q357-D363 HydrophobicContact CB-CB 4.12Å; Q357-D363 WeakPolarHBondContact CB-OD2 3.49Å; Q357-D363 WeakPolarHBondContact CG-OD2 3.36Å; P361-D363 PolarHBondContact O-N 3.11Å; D363-I365 PolarHBondContact O-N 3.37Å; D363-L366 PolarHBondContact O-N 3.26Å; D363-I367 WeakPolarHBondContact O-CG1 3.25Å; D363-I367 PolarHBondContact O-N 3.4Å; D363-Y432 WeakPolarHBondContact CB-OH 3.42Å; D363-Y432 PolarHBondContact OD2-OH 3.33Å
364	Y	81.9	Confident	83.9	Confident	49 Å²	49	48.6 Å²	48.6	19%	0.192	26%	0.256	C	S	.	.	H	α-helix	trans	-57.6	-47.2	172.6	-173.2	-83.7	0	0	0	111.9	L18 P62 V63 P361 L366 I367 T368	L18-Y364 WeakPolarHBondContact CD2-OH 3.5Å; P62-Y364 HydrophobicContact CB-CD2 3.44Å; P62-Y364 VanDerWaalsContact CB-CD2 3.44Å; P62-Y364 HydrophobicContact CB-CE2 3.58Å; P62-Y364 HydrophobicContact CB-CG 4.19Å; P62-Y364 HydrophobicContact CG-CD2 3.79Å; P62-Y364 HydrophobicContact CG-CE2 3.38Å; V63-Y364 HydrophobicContact CG2-CE2 3.8Å; P361-Y364 PolarHBondContact O-N 3.45Å; Y364-L366 VanDerWaalsContact C-N 3.33Å; Y364-L366 PolarHBondContact O-N 2.95Å; Y364-I367 PolarHBondContact O-N 3.42Å; Y364-T368 WeakPolarHBondContact O-CB 3.34Å; Y364-T368 PolarHBondContact O-N 3.42Å; Y364-T368 PolarHBondContact O-OG1 3.2Å
365	I	84.4	Confident	84.5	Confident	79 Å²	79	47.8 Å²	47.8	41%	0.405	25%	0.251	S	S	.	.	H	α-helix	trans	-62.1	-44	177.8	-66.1	168.8	0	0	0	109.7	P361 L362 D363 T368 I369	P361-I365 HydrophobicContact CG-CD1 4.25Å; P361-I365 WeakPolarHBondContact O-CG1 3.42Å; P361-I365 PolarHBondContact O-N 3.33Å; L362-I365 PolarHBondContact O-N 3.11Å; D363-I365 PolarHBondContact O-N 3.37Å; I365-T368 PolarHBondContact O-N 2.9Å; I365-I369 HydrophobicContact CG2-CD1 3.76Å; I365-I369 HydrophobicContact CG2-CG1 4.39Å; I365-I369 VanDerWaalsContact O-CG1 3.27Å; I365-I369 WeakPolarHBondContact O-CG1 3.35Å; I365-I369 PolarHBondContact O-N 3.48Å
366	L	87.9	Confident	84.9	Confident	39 Å²	39	46.7 Å²	46.7	20%	0.204	24%	0.242	C	C	.	.	H	α-helix	trans	-63.1	-47.3	179.4	-176.8	61	0	0	0	111.9	L352 L353 L356 L362 D363 Y364 T368 I369 I370	L352-L366 HydrophobicContact CD2-CD2 4.15Å; L352-L366 HydrophobicContact CG-CD2 4.42Å; L353-L366 HydrophobicContact CD2-CB 4.49Å; L353-L366 HydrophobicContact CD2-CD2 3.8Å; L353-L366 HydrophobicContact CD2-CG 4.28Å; L353-L366 HydrophobicContact CG-CD2 4.48Å; L356-L366 HydrophobicContact CD1-CB 4.45Å; L356-L366 HydrophobicContact CD1-CD2 3.3Å; L356-L366 HydrophobicContact CD1-CG 4.45Å; L362-L366 PolarHBondContact O-N 2.94Å; D363-L366 PolarHBondContact O-N 3.26Å; Y364-L366 VanDerWaalsContact C-N 3.33Å; Y364-L366 PolarHBondContact O-N 2.95Å; L366-T368 VanDerWaalsContact C-N 3.27Å; L366-T368 PolarHBondContact O-N 3.23Å; L366-I369 WeakPolarHBondContact O-CB 3.12Å; L366-I369 PolarHBondContact O-N 3.49Å; L366-I369 VanDerWaalsContact O-N 3.1Å; L366-I370 HydrophobicContact CD1-CG1 4.45Å; L366-I370 HydrophobicContact CG-CD1 4.07Å; L366-I370 HydrophobicContact CG-CG1 4.43Å; L366-I370 VanDerWaalsContact O-CG1 3.25Å; L366-I370 WeakPolarHBondContact O-CG1 3.01Å; L366-I370 PolarHBondContact O-N 3.01Å
367	I	87.4	Confident	85.5	Confident	2 Å²	2	44.7 Å²	44.7	1%	0.01	23%	0.231	C	C	.	.	H	α-helix	trans	-59.9	-40.9	177.6	-64.9	166.1	0	0	0	110.8	P62 I65 L353 D363 Y364 I369 I370 I371 I425 Y432	P62-I367 HydrophobicContact CB-CB 4.27Å; P62-I367 HydrophobicContact CB-CD1 4.07Å; P62-I367 HydrophobicContact CB-CG2 4.11Å; P62-I367 HydrophobicContact CG-CG2 4.36Å; I65-I367 HydrophobicContact CD1-CD1 4.03Å; L353-I367 HydrophobicContact CD2-CD1 4.48Å; L353-I367 HydrophobicContact CD2-CG1 3.95Å; D363-I367 WeakPolarHBondContact O-CG1 3.25Å; D363-I367 PolarHBondContact O-N 3.4Å; Y364-I367 PolarHBondContact O-N 3.42Å; I367-I369 PolarHBondContact O-N 3.22Å; I367-I370 WeakPolarHBondContact O-CB 3.45Å; I367-I370 PolarHBondContact O-N 3.12Å; I367-I371 HydrophobicContact CG2-CD1 3.99Å; I367-I371 WeakPolarHBondContact O-CG1 3.47Å; I367-I371 PolarHBondContact O-N 3.46Å; I367-I425 HydrophobicContact CG2-CD1 4.34Å; I367-Y432 HydrophobicContact CD1-CE1 3.64Å
368	T	86.1	Confident	86.3	Confident	39 Å²	39	43.5 Å²	43.5	24%	0.239	23%	0.225	C	C	.	.	H	α-helix	trans	-62.7	-41.9	175.4	-56.6	0	0	0	0	111.6	Y364 I365 L366 I370 I371 M372	Y364-T368 WeakPolarHBondContact O-CB 3.34Å; Y364-T368 PolarHBondContact O-N 3.42Å; Y364-T368 PolarHBondContact O-OG1 3.2Å; I365-T368 PolarHBondContact O-N 2.9Å; L366-T368 VanDerWaalsContact C-N 3.27Å; L366-T368 PolarHBondContact O-N 3.23Å; T368-I370 VanDerWaalsContact C-N 3.34Å; T368-I370 PolarHBondContact O-N 2.95Å; T368-I371 PolarHBondContact O-N 3.45Å; T368-M372 WeakPolarHBondContact O-CB 3.2Å; T368-M372 WeakPolarHBondContact O-CG 3.48Å; T368-M372 PolarHBondContact O-N 3.35Å
369	I	89.4	Confident	86.9	Confident	96 Å²	96	39.9 Å²	39.9	49%	0.492	20%	0.202	S	C	.	.	H	α-helix	trans	-62.1	-41.5	174	-70.9	167	0	0	0	110.9	I365 L366 I367 M372 Y373	I365-I369 HydrophobicContact CG2-CD1 3.76Å; I365-I369 HydrophobicContact CG2-CG1 4.39Å; I365-I369 VanDerWaalsContact O-CG1 3.27Å; I365-I369 WeakPolarHBondContact O-CG1 3.35Å; I365-I369 PolarHBondContact O-N 3.48Å; L366-I369 WeakPolarHBondContact O-CB 3.12Å; L366-I369 PolarHBondContact O-N 3.49Å; L366-I369 VanDerWaalsContact O-N 3.1Å; I367-I369 PolarHBondContact O-N 3.22Å; I369-M372 PolarHBondContact O-N 2.99Å; I369-Y373 WeakPolarHBondContact O-CB 3.48Å; I369-Y373 PolarHBondContact O-N 3.41Å
370	I	91.4	Very high	87.5	Confident	9 Å²	9	36.2 Å²	36.2	5%	0.046	18%	0.181	C	C	.	.	H	α-helix	trans	-61	-48.1	176.5	-65.2	169.3	0	0	0	110.2	F316 L366 I367 T368 M372 Y373 F374 I425 L428	F316-I370 HydrophobicContact CE1-CD1 4.22Å; F316-I370 HydrophobicContact CE1-CG1 3.98Å; F316-I370 HydrophobicContact CE1-CG2 3.9Å; F316-I370 HydrophobicContact CZ-CB 4.21Å; F316-I370 HydrophobicContact CZ-CG1 3.8Å; F316-I370 HydrophobicContact CZ-CG2 3.79Å; L366-I370 HydrophobicContact CD1-CG1 4.45Å; L366-I370 HydrophobicContact CG-CD1 4.07Å; L366-I370 HydrophobicContact CG-CG1 4.43Å; L366-I370 VanDerWaalsContact O-CG1 3.25Å; L366-I370 WeakPolarHBondContact O-CG1 3.01Å; L366-I370 PolarHBondContact O-N 3.01Å; I367-I370 WeakPolarHBondContact O-CB 3.45Å; I367-I370 PolarHBondContact O-N 3.12Å; T368-I370 VanDerWaalsContact C-N 3.34Å; T368-I370 PolarHBondContact O-N 2.95Å; I370-M372 PolarHBondContact O-N 3.38Å; I370-Y373 WeakPolarHBondContact O-CB 3.44Å; I370-Y373 PolarHBondContact O-N 2.85Å; I370-F374 HydrophobicContact CG2-CD2 3.8Å; I370-F374 HydrophobicContact CG2-CE2 3.52Å; I370-F374 VanDerWaalsContact O-CD2 3.23Å; I370-F374 WeakPolarHBondContact O-CD2 3.25Å; I370-F374 PolarHBondContact O-N 3.36Å; I370-I425 HydrophobicContact CG2-CG1 4.38Å; I370-L428 HydrophobicContact CG2-CD1 4.39Å
371	I	91.1	Very high	88.7	Confident	8 Å²	8	29.9 Å²	29.9	4%	0.041	15%	0.153	C	C	.	.	H	α-helix	trans	-58.8	-48.9	177.1	-67.8	163.6	0	0	0	110.4	I367 T368 Y373 F374 I375 T421 I425	I367-I371 HydrophobicContact CG2-CD1 3.99Å; I367-I371 WeakPolarHBondContact O-CG1 3.47Å; I367-I371 PolarHBondContact O-N 3.46Å; T368-I371 PolarHBondContact O-N 3.45Å; I371-Y373 VanDerWaalsContact C-N 3.31Å; I371-Y373 PolarHBondContact O-N 3.44Å; I371-F374 PolarHBondContact O-N 3.25Å; I371-I375 HydrophobicContact CG2-CD1 3.8Å; I371-I375 WeakPolarHBondContact O-CD1 3.49Å; I371-I375 WeakPolarHBondContact O-CG1 3.43Å; I371-I375 PolarHBondContact O-N 3.47Å; I371-T421 HydrophobicContact CG1-CG2 4.47Å; I371-I425 HydrophobicContact CD1-CD1 4.03Å; I371-I425 HydrophobicContact CG1-CD1 3.49Å; I371-I425 VanDerWaalsContact CG1-CD1 3.49Å
372	M	90.7	Very high	89.5	Confident	46 Å²	46	27.5 Å²	27.5	23%	0.227	14%	0.137	C	C	.	.	H	α-helix	trans	-62.4	-38.7	179	-71.8	-64	155.9	0	0	112	L55 T368 I369 I370 I375 F376	L55-M372 HydrophobicContact CD2-CE 4.45Å; T368-M372 WeakPolarHBondContact O-CB 3.2Å; T368-M372 WeakPolarHBondContact O-CG 3.48Å; T368-M372 PolarHBondContact O-N 3.35Å; I369-M372 PolarHBondContact O-N 2.99Å; I370-M372 PolarHBondContact O-N 3.38Å; M372-I375 HydrophobicContact CE-CD1 4.41Å; M372-I375 PolarHBondContact O-N 3.4Å; M372-I375 HydrophobicContact SD-CD1 4.13Å; M372-F376 HydrophobicContact CB-CD2 4.34Å; M372-F376 HydrophobicContact CB-CE2 4.12Å; M372-F376 WeakPolarHBondContact O-CD2 3.09Å; M372-F376 WeakPolarHBondContact O-CG 3.32Å; M372-F376 PolarHBondContact O-N 3.16Å
373	Y	93.5	Very high	89.8	Confident	9 Å²	9	30.3 Å²	30.3	4%	0.035	14%	0.143	C	C	.	.	H	α-helix	trans	-60	-46.1	174.2	171.9	-93.8	0	0	0	112	M213 F309 V312 A313 F316 I369 I370 I371 I375 F376 T377	M213-Y373 HydrophobicContact CG-CE1 3.97Å; M213-Y373 HydrophobicContact SD-CE1 3.93Å; F309-Y373 HydrophobicContact CB-CE2 4.45Å; F309-Y373 AromaticContact CD1-CD2 3.66Å; F309-Y373 HydrophobicContact CD1-CD2 3.66Å; F309-Y373 AromaticContact CD1-CE2 3.54Å; F309-Y373 HydrophobicContact CD1-CE2 3.54Å; F309-Y373 AromaticContact CE1-CD2 3.85Å; F309-Y373 HydrophobicContact CE1-CD2 3.85Å; F309-Y373 HydrophobicContact CE1-CE2 4.2Å; F309-Y373 HydrophobicContact CG-CE2 4.34Å; V312-Y373 HydrophobicContact CG1-CD1 4.44Å; V312-Y373 HydrophobicContact CG1-CD2 4.15Å; V312-Y373 HydrophobicContact CG1-CE1 4.31Å; V312-Y373 HydrophobicContact CG1-CE2 4.01Å; V312-Y373 HydrophobicContact CG1-CG 4.34Å; A313-Y373 WeakPolarHBondContact CB-OH 3.25Å; F316-Y373 AromaticContact CD2-CD1 3.98Å; F316-Y373 HydrophobicContact CD2-CD1 3.98Å; F316-Y373 AromaticContact CD2-CE1 3.61Å; F316-Y373 HydrophobicContact CD2-CE1 3.61Å; F316-Y373 AromaticContact CE2-CD1 3.36Å; F316-Y373 HydrophobicContact CE2-CD1 3.36Å; F316-Y373 AromaticContact CE2-CE1 3.45Å; F316-Y373 HydrophobicContact CE2-CE1 3.45Å; F316-Y373 VanDerWaalsContact CE2-CE1 3.45Å; F316-Y373 HydrophobicContact CE2-CG 4.14Å; F316-Y373 HydrophobicContact CZ-CD1 4.34Å; I369-Y373 WeakPolarHBondContact O-CB 3.48Å; I369-Y373 PolarHBondContact O-N 3.41Å; I370-Y373 WeakPolarHBondContact O-CB 3.44Å; I370-Y373 PolarHBondContact O-N 2.85Å; I371-Y373 VanDerWaalsContact C-N 3.31Å; I371-Y373 PolarHBondContact O-N 3.44Å; Y373-I375 VanDerWaalsContact C-N 3.3Å; Y373-I375 PolarHBondContact O-N 2.84Å; Y373-F376 PolarHBondContact O-N 3.04Å; Y373-T377 HydrophobicContact CD1-CG2 4.34Å; Y373-T377 HydrophobicContact CD2-CG2 4.12Å; Y373-T377 HydrophobicContact CE1-CG2 3.93Å; Y373-T377 HydrophobicContact CE2-CG2 3.68Å; Y373-T377 HydrophobicContact CG-CG2 4.45Å; Y373-T377 WeakPolarHBondContact O-CB 3.32Å; Y373-T377 WeakPolarHBondContact O-CG2 3.22Å; Y373-T377 PolarHBondContact O-N 2.91Å; Y373-T377 PolarHBondContact O-OG1 2.99Å
374	F	94.1	Very high	89.9	Confident	0 Å²	0	31.6 Å²	31.6	0%	0	15%	0.15	C	C	.	.	H	α-helix	trans	-61.7	-39.1	175.9	-78.3	-59.8	0	0	0	112	T209 M213 F316 I370 I371 T377 S378 T421 M424 L428 F498	T209-F374 HydrophobicContact CG2-CD1 3.64Å; T209-F374 HydrophobicContact CG2-CE1 4.38Å; M213-F374 HydrophobicContact SD-CD1 4.32Å; M213-F374 HydrophobicContact SD-CE1 3.81Å; F316-F374 HydrophobicContact CD2-CZ 4.36Å; F316-F374 HydrophobicContact CG-CZ 4.42Å; I370-F374 HydrophobicContact CG2-CD2 3.8Å; I370-F374 HydrophobicContact CG2-CE2 3.52Å; I370-F374 VanDerWaalsContact O-CD2 3.23Å; I370-F374 WeakPolarHBondContact O-CD2 3.25Å; I370-F374 PolarHBondContact O-N 3.36Å; I371-F374 PolarHBondContact O-N 3.25Å; F374-T377 WeakPolarHBondContact CA-OG1 3.21Å; F374-T377 PolarHBondContact O-OG1 3.25Å; F374-S378 VanDerWaalsContact O-CB 3.27Å; F374-S378 WeakPolarHBondContact O-CB 3.21Å; F374-S378 PolarHBondContact O-N 3.34Å; F374-S378 PolarHBondContact O-OG 3.18Å; F374-T421 HydrophobicContact CB-CG2 3.85Å; F374-T421 HydrophobicContact CD2-CG2 3.59Å; F374-T421 HydrophobicContact CE2-CG2 4.46Å; F374-T421 HydrophobicContact CG-CG2 3.97Å; F374-M424 HydrophobicContact CD1-CE 3.32Å; F374-M424 HydrophobicContact CD2-CE 3.99Å; F374-M424 HydrophobicContact CE1-CE 3.17Å; F374-M424 HydrophobicContact CE1-SD 3.81Å; F374-M424 HydrophobicContact CE2-CE 3.86Å; F374-M424 HydrophobicContact CG-CE 3.74Å; F374-M424 HydrophobicContact CZ-CE 3.47Å; F374-M424 VanDerWaalsContact CZ-CE 3.47Å; F374-M424 HydrophobicContact CZ-CG 4.29Å; F374-M424 HydrophobicContact CZ-SD 3.91Å; F374-L428 HydrophobicContact CE2-CD1 3.82Å; F374-L428 HydrophobicContact CZ-CD1 3.92Å; F374-F498 HydrophobicContact CE1-CZ 4.46Å
375	I	92.8	Very high	90.1	Very high	2 Å²	2	32 Å²	32	1%	0.01	15%	0.154	C	C	.	.	H	α-helix	trans	-64.9	-48.5	175	-63.6	158.3	0	0	0	110.6	F25 L55 I371 M372 Y373 T377 S378 M379 V418	F25-I375 HydrophobicContact CE1-CG2 4.42Å; F25-I375 HydrophobicContact CZ-CG2 4.07Å; L55-I375 HydrophobicContact CD2-CD1 3.27Å; L55-I375 HydrophobicContact CD2-CG1 4.46Å; I371-I375 HydrophobicContact CG2-CD1 3.8Å; I371-I375 WeakPolarHBondContact O-CD1 3.49Å; I371-I375 WeakPolarHBondContact O-CG1 3.43Å; I371-I375 PolarHBondContact O-N 3.47Å; M372-I375 HydrophobicContact CE-CD1 4.41Å; M372-I375 PolarHBondContact O-N 3.4Å; M372-I375 HydrophobicContact SD-CD1 4.13Å; Y373-I375 VanDerWaalsContact C-N 3.3Å; Y373-I375 PolarHBondContact O-N 2.84Å; I375-T377 PolarHBondContact O-N 2.93Å; I375-S378 PolarHBondContact O-N 3.39Å; I375-M379 HydrophobicContact CB-CE 4.48Å; I375-M379 HydrophobicContact CG2-CE 3.52Å; I375-M379 HydrophobicContact CG2-CG 4.39Å; I375-M379 HydrophobicContact CG2-SD 4.08Å; I375-M379 WeakPolarHBondContact O-CB 3.04Å; I375-M379 WeakPolarHBondContact O-CE 3.27Å; I375-M379 VanDerWaalsContact O-CG 3.25Å; I375-M379 WeakPolarHBondContact O-CG 3.3Å; I375-M379 PolarHBondContact O-N 3.3Å; I375-V418 HydrophobicContact CD1-CG2 4.02Å; I375-V418 HydrophobicContact CG1-CG2 3.76Å
376	F	92.5	Very high	90.2	Very high	95 Å²	95	28.3 Å²	28.3	42%	0.417	14%	0.137	S	C	.	.	H	α-helix	trans	-60.5	-42.2	179.8	-75.6	-58.4	0	0	0	113.4	F25 M372 Y373 M379 A380	F25-F376 HydrophobicContact CE2-CE1 4.1Å; F25-F376 AromaticContact CE2-CZ 3.95Å; F25-F376 HydrophobicContact CE2-CZ 3.95Å; M372-F376 HydrophobicContact CB-CD2 4.34Å; M372-F376 HydrophobicContact CB-CE2 4.12Å; M372-F376 WeakPolarHBondContact O-CD2 3.09Å; M372-F376 WeakPolarHBondContact O-CG 3.32Å; M372-F376 PolarHBondContact O-N 3.16Å; Y373-F376 PolarHBondContact O-N 3.04Å; F376-M379 VanDerWaalsContact CA-CE 3.47Å; F376-M379 HydrophobicContact CB-CE 4.28Å; F376-M379 HydrophobicContact CD1-CE 3.24Å; F376-M379 HydrophobicContact CE1-CE 3.7Å; F376-M379 HydrophobicContact CG-CE 3.95Å; F376-M379 PolarHBondContact O-N 3.17Å; F376-A380 PolarHBondContact O-N 3.4Å
377	T	94.5	Very high	90.1	Very high	0 Å²	0	26.8 Å²	26.8	0%	0	13%	0.129	C	C	.	.	H	α-helix	trans	-68.1	-43.7	177.5	51.9	0	0	0	0	111.1	G212 M213 L216 Y373 F374 I375 M379 A380 G381	G212-T377 VanDerWaalsContact CA-O 3.25Å; G212-T377 WeakPolarHBondContact CA-O 3.41Å; M213-T377 HydrophobicContact CB-CG2 4.38Å; M213-T377 HydrophobicContact CG-CG2 3.87Å; L216-T377 HydrophobicContact CD1-CG2 4.34Å; Y373-T377 HydrophobicContact CD1-CG2 4.34Å; Y373-T377 HydrophobicContact CD2-CG2 4.12Å; Y373-T377 HydrophobicContact CE1-CG2 3.93Å; Y373-T377 HydrophobicContact CE2-CG2 3.68Å; Y373-T377 HydrophobicContact CG-CG2 4.45Å; Y373-T377 WeakPolarHBondContact O-CB 3.32Å; Y373-T377 WeakPolarHBondContact O-CG2 3.22Å; Y373-T377 PolarHBondContact O-N 2.91Å; Y373-T377 PolarHBondContact O-OG1 2.99Å; F374-T377 WeakPolarHBondContact CA-OG1 3.21Å; F374-T377 PolarHBondContact O-OG1 3.25Å; I375-T377 PolarHBondContact O-N 2.93Å; T377-M379 VanDerWaalsContact C-N 3.35Å; T377-M379 PolarHBondContact O-N 3.25Å; T377-A380 PolarHBondContact O-N 2.95Å; T377-A380 VanDerWaalsContact O-N 3.13Å; T377-G381 PolarHBondContact O-N 3.25Å
378	S	94.8	Very high	89.9	Confident	0 Å²	0	33 Å²	33	0%	0	15%	0.152	C	C	.	.	H	α-helix	trans	-57.1	-46.6	173.5	-55.7	0	0	0	0	112.1	T209 F374 I375 A380 G381 I382 I417	T209-S378 WeakPolarHBondContact CB-OG 3.44Å; T209-S378 WeakPolarHBondContact CG2-OG 3.26Å; T209-S378 PolarHBondContact OG1-OG 3.35Å; F374-S378 VanDerWaalsContact O-CB 3.27Å; F374-S378 WeakPolarHBondContact O-CB 3.21Å; F374-S378 PolarHBondContact O-N 3.34Å; F374-S378 PolarHBondContact O-OG 3.18Å; I375-S378 PolarHBondContact O-N 3.39Å; S378-A380 VanDerWaalsContact C-N 3.31Å; S378-A380 PolarHBondContact O-N 2.86Å; S378-G381 WeakPolarHBondContact O-CA 3.42Å; S378-G381 PolarHBondContact O-N 2.95Å; S378-G381 VanDerWaalsContact O-N 3.1Å; S378-I382 VanDerWaalsContact O-CG1 3.31Å; S378-I382 WeakPolarHBondContact O-CG1 3.15Å; S378-I382 PolarHBondContact O-N 2.99Å; S378-I417 WeakPolarHBondContact OG-CG2 3.4Å
379	M	90.7	Very high	89.5	Confident	17 Å²	17	37.4 Å²	37.4	8%	0.084	17%	0.168	C	C	.	.	H	α-helix	trans	-59.3	-41.4	176.4	-71.9	-175.8	-68.6	0	0	112.2	F25 Y29 I375 F376 T377 R383 L414	F25-M379 HydrophobicContact CZ-CE 4.13Å; Y29-M379 HydrophobicContact CD2-SD 3.43Å; Y29-M379 WeakPolarHBondContact CD2-SD 3.48Å; Y29-M379 HydrophobicContact CE2-CG 3.93Å; Y29-M379 HydrophobicContact CE2-SD 3.08Å; Y29-M379 WeakPolarHBondContact CE2-SD 2.86Å; Y29-M379 HydrophobicContact CG-SD 4.47Å; I375-M379 HydrophobicContact CB-CE 4.48Å; I375-M379 HydrophobicContact CG2-CE 3.52Å; I375-M379 HydrophobicContact CG2-CG 4.39Å; I375-M379 HydrophobicContact CG2-SD 4.08Å; I375-M379 WeakPolarHBondContact O-CB 3.04Å; I375-M379 WeakPolarHBondContact O-CE 3.27Å; I375-M379 VanDerWaalsContact O-CG 3.25Å; I375-M379 WeakPolarHBondContact O-CG 3.3Å; I375-M379 PolarHBondContact O-N 3.3Å; F376-M379 VanDerWaalsContact CA-CE 3.47Å; F376-M379 HydrophobicContact CB-CE 4.28Å; F376-M379 HydrophobicContact CD1-CE 3.24Å; F376-M379 HydrophobicContact CE1-CE 3.7Å; F376-M379 HydrophobicContact CG-CE 3.95Å; F376-M379 PolarHBondContact O-N 3.17Å; T377-M379 VanDerWaalsContact C-N 3.35Å; T377-M379 PolarHBondContact O-N 3.25Å; M379-R383 WeakPolarHBondContact O-CB 3.31Å; M379-R383 PolarHBondContact O-N 2.88Å; M379-L414 HydrophobicContact CG-CD1 4.13Å; M379-L414 HydrophobicContact CG-CD2 3.97Å
380	A	90.3	Very high	88.5	Confident	8 Å²	8	41.1 Å²	41.1	7%	0.066	18%	0.181	C	C	.	.	H	α-helix	trans	-68.4	-34.9	175.5	0	0	0	0	0	112.9	L216 F376 T377 S378 N384	L216-A380 HydrophobicContact CB-CB 3.9Å; L216-A380 HydrophobicContact CD1-CB 3.72Å; L216-A380 HydrophobicContact CG-CB 4.19Å; F376-A380 PolarHBondContact O-N 3.4Å; T377-A380 PolarHBondContact O-N 2.95Å; T377-A380 VanDerWaalsContact O-N 3.13Å; S378-A380 VanDerWaalsContact C-N 3.31Å; S378-A380 PolarHBondContact O-N 2.86Å; A380-N384 WeakPolarHBondContact O-CB 3.5Å; A380-N384 PolarHBondContact O-N 2.68Å; A380-N384 VanDerWaalsContact O-N 3.09Å; A380-N384 PolarHBondContact O-ND2 3.24Å
381	G	91.4	Very high	87.9	Confident	0 Å²	0	51.8 Å²	51.8	0%	0	22%	0.221	C	C	.	.	H	α-helix	trans	-62.4	-55.1	173.3	0	0	0	0	0	112.2	Y208 T377 S378 R383 N384 I385	Y208-G381 WeakPolarHBondContact O-CA 3.08Å; T377-G381 PolarHBondContact O-N 3.25Å; S378-G381 WeakPolarHBondContact O-CA 3.42Å; S378-G381 PolarHBondContact O-N 2.95Å; S378-G381 VanDerWaalsContact O-N 3.1Å; G381-R383 VanDerWaalsContact C-N 3.29Å; G381-R383 PolarHBondContact O-N 3.3Å; G381-N384 PolarHBondContact O-N 2.88Å; G381-N384 VanDerWaalsContact O-N 3.11Å; G381-I385 PolarHBondContact O-N 3.43Å
382	I	91.3	Very high	87.4	Confident	1 Å²	1	57.5 Å²	57.5	1%	0.005	25%	0.25	C	C	.	.	H	α-helix	trans	-60.6	-39.8	179.7	-53.5	164.6	0	0	0	110.6	Y208 S378 N384 G386 I387 I397 L410 I413 L414 I417	Y208-I382 HydrophobicContact CD1-CB 4.14Å; Y208-I382 HydrophobicContact CD1-CG1 3.67Å; Y208-I382 HydrophobicContact CD2-CG1 3.91Å; Y208-I382 HydrophobicContact CE1-CB 4.42Å; Y208-I382 HydrophobicContact CE1-CG1 4.19Å; Y208-I382 HydrophobicContact CE1-CG2 4.39Å; Y208-I382 HydrophobicContact CE2-CG1 4.41Å; Y208-I382 HydrophobicContact CG-CB 4.46Å; Y208-I382 HydrophobicContact CG-CG1 3.5Å; S378-I382 VanDerWaalsContact O-CG1 3.31Å; S378-I382 WeakPolarHBondContact O-CG1 3.15Å; S378-I382 PolarHBondContact O-N 2.99Å; I382-N384 PolarHBondContact O-N 2.69Å; I382-G386 VanDerWaalsContact O-CA 3.25Å; I382-G386 WeakPolarHBondContact O-CA 3.33Å; I382-G386 PolarHBondContact O-N 2.99Å; I382-I387 HydrophobicContact CG2-CG1 4.06Å; I382-I397 HydrophobicContact CB-CD1 4.38Å; I382-I397 HydrophobicContact CG2-CD1 3.3Å; I382-I397 HydrophobicContact CG2-CG1 4.33Å; I382-L410 HydrophobicContact CB-CD1 4.48Å; I382-L410 HydrophobicContact CD1-CD1 3.79Å; I382-L410 HydrophobicContact CG2-CD1 4.05Å; I382-I413 HydrophobicContact CD1-CG2 3.87Å; I382-L414 HydrophobicContact CD1-CD2 3.92Å; I382-L414 HydrophobicContact CD1-CG 4.15Å; I382-I417 HydrophobicContact CD1-CD1 4.44Å
383	R	87	Confident	86.9	Confident	132 Å²	132	62.2 Å²	62.2	50%	0.498	27%	0.265	S	S	.	.	H	α-helix	trans	-62.7	-40.4	176.1	-176	-173.8	64.3	160.7	-2.4	112.8	M379 G381	M379-R383 WeakPolarHBondContact O-CB 3.31Å; M379-R383 PolarHBondContact O-N 2.88Å; G381-R383 VanDerWaalsContact C-N 3.29Å; G381-R383 PolarHBondContact O-N 3.3Å
384	N	84.3	Confident	86.4	Confident	33 Å²	33	65.6 Å²	65.6	18%	0.176	28%	0.284	C	S	.	.	H	α-helix	trans	-79.7	-31.9	-176.1	-80	-31.5	0	0	0	113	Y211 N219 A380 G381 I382 K515	Y211-N384 HydrophobicContact CE1-CB 3.8Å; N219-N384 PolarHBondContact ND2-ND2 3.3Å; A380-N384 WeakPolarHBondContact O-CB 3.5Å; A380-N384 PolarHBondContact O-N 2.68Å; A380-N384 VanDerWaalsContact O-N 3.09Å; A380-N384 PolarHBondContact O-ND2 3.24Å; G381-N384 PolarHBondContact O-N 2.88Å; G381-N384 VanDerWaalsContact O-N 3.11Å; I382-N384 PolarHBondContact O-N 2.69Å; N384-K515 PolarHBondContact OD1-NZ 2.85Å
385	I	86.9	Confident	86	Confident	56 Å²	56	67.3 Å²	67.3	29%	0.287	29%	0.29	S	S	.	.	H	α-helix	trans	-93.3	-37.1	-178.3	-65.2	171.7	0	0	0	111.6	Y208 Y211 G381 W388	Y208-I385 HydrophobicContact CD1-CB 4.43Å; Y208-I385 HydrophobicContact CD1-CD1 4.25Å; Y208-I385 HydrophobicContact CE1-CB 4.12Å; Y208-I385 HydrophobicContact CE1-CG2 4.03Å; Y211-I385 HydrophobicContact CD1-CD1 3.41Å; Y211-I385 VanDerWaalsContact CD1-CD1 3.41Å; Y211-I385 HydrophobicContact CD1-CG1 3.74Å; Y211-I385 HydrophobicContact CE1-CD1 4Å; Y211-I385 HydrophobicContact CE1-CG1 3.78Å; Y211-I385 HydrophobicContact CG-CD1 3.81Å; Y211-I385 HydrophobicContact CG-CG1 4.49Å; G381-I385 PolarHBondContact O-N 3.43Å; I385-W388 HydrophobicContact CG2-CG 4.5Å; I385-W388 PolarHBondContact O-NE1 3.27Å
386	G	85.3	Confident	85.5	Confident	3 Å²	3	71 Å²	71	3%	0.031	31%	0.307	C	S	.	.			trans	84.9	174.9	-165.3	0	0	0	0	0	112.6	Y208 I382	Y208-G386 VanDerWaalsContact CE1-O 3.23Å; Y208-G386 WeakPolarHBondContact CE1-O 3.33Å; Y208-G386 PolarHBondContact OH-O 3.27Å; I382-G386 VanDerWaalsContact O-CA 3.25Å; I382-G386 WeakPolarHBondContact O-CA 3.33Å; I382-G386 PolarHBondContact O-N 2.99Å
387	I	86.1	Confident	85.1	Confident	7 Å²	7	67 Å²	67	4%	0.036	29%	0.289	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-86.3	120.4	174	-57.5	179	0	0	0	108.3	Y208 I382 L394 Y395 I397 F409 L410 I413	Y208-I387 WeakPolarHBondContact OH-CA 3.22Å; I382-I387 HydrophobicContact CG2-CG1 4.06Å; I387-L394 PolarHBondContact O-N 2.96Å; I387-Y395 HydrophobicContact CD1-CD2 4.44Å; I387-Y395 PolarHBondContact N-O 3.41Å; I387-Y395 PolarHBondContact O-N 2.89Å; I387-I397 HydrophobicContact CD1-CD1 3.97Å; I387-I397 HydrophobicContact CD1-CG1 4.32Å; I387-I397 HydrophobicContact CG1-CD1 3.97Å; I387-I397 HydrophobicContact CG1-CG1 4.24Å; I387-F409 HydrophobicContact CD1-CB 4.05Å; I387-L410 HydrophobicContact CD1-CB 4.46Å; I387-I413 HydrophobicContact CD1-CD1 4.15Å; I387-I413 HydrophobicContact CG1-CD1 4.14Å; I387-I413 HydrophobicContact CG2-CD1 3.88Å
388	W	83.1	Confident	84.3	Confident	132 Å²	132	71.1 Å²	71.1	50%	0.5	31%	0.305	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-111.9	142.6	-179	-75.6	58.9	0	0	0	110.4	Y208 I385 W391 I392	Y208-W388 PolarHBondContact OH-N 2.88Å; I385-W388 HydrophobicContact CG2-CG 4.5Å; I385-W388 PolarHBondContact O-NE1 3.27Å; W388-W391 WeakPolarHBondContact CZ3-O 3.24Å; W388-I392 WeakPolarHBondContact CA-O 3.49Å
389	F	77.9	Confident	83.7	Confident	131 Å²	131	79.8 Å²	79.8	58%	0.575	34%	0.337	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-134.9	116.4	173.6	-170.9	-110	0	0	0	109.1	W391 I392	F389-W391 PolarHBondContact O-N 2.97Å; F389-I392 PolarHBondContact N-O 3.44Å; F389-I392 PolarHBondContact O-N 3.26Å
390	F	68.3	Low	83.1	Confident	174 Å²	174	79.8 Å²	79.8	76%	0.763	34%	0.342	S	S	*	.	T	Hydrogen-bonded Turn	trans	43.7	30.6	-179.5	-59.3	-69.3	0	0	0	116.1
391	W	78.6	Confident	82.5	Confident	233 Å²	233	84 Å²	84	88%	0.883	36%	0.356	S	S	*	.	T	Hydrogen-bonded Turn	trans	100.7	-2.6	174.9	-51.8	17.7	0	0	0	116.1	W388 F389	W388-W391 WeakPolarHBondContact CZ3-O 3.24Å; F389-W391 PolarHBondContact O-N 2.97Å
392	I	80.5	Confident	82.2	Confident	128 Å²	128	84.2 Å²	84.2	66%	0.656	36%	0.358	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-98.8	132.9	171.5	-61.3	163.5	0	0	0	108.6	W388 F389 L394	W388-I392 WeakPolarHBondContact CA-O 3.49Å; F389-I392 PolarHBondContact N-O 3.44Å; F389-I392 PolarHBondContact O-N 3.26Å; I392-L394 PolarHBondContact O-N 3.42Å; I392-L394 VanDerWaalsContact O-N 3.13Å
393	R	81.7	Confident	81.9	Confident	145 Å²	145	91.3 Å²	91.3	55%	0.547	38%	0.384	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-76.9	97.8	172.6	-174.3	-179.9	66.8	-176.3	-2.7	108.9
394	L	83.4	Confident	81.9	Confident	81 Å²	81	85.9 Å²	85.9	42%	0.424	37%	0.366	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-69.6	-49.9	-176.9	-169.3	69.9	0	0	0	111.4	I387 I392	I387-L394 PolarHBondContact O-N 2.96Å; I392-L394 PolarHBondContact O-N 3.42Å; I392-L394 VanDerWaalsContact O-N 3.13Å
395	Y	83.7	Confident	82.1	Confident	36 Å²	36	85.2 Å²	85.2	14%	0.141	36%	0.362	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-134.7	134.6	-179.2	-59.5	-67.5	0	0	0	112.3	I387 Q405 A406 F409	I387-Y395 HydrophobicContact CD1-CD2 4.44Å; I387-Y395 PolarHBondContact N-O 3.41Å; I387-Y395 PolarHBondContact O-N 2.89Å; Y395-Q405 PolarHBondContact OH-OE1 2.93Å; Y395-A406 HydrophobicContact CD1-CB 3.64Å; Y395-A406 HydrophobicContact CD2-CB 4.04Å; Y395-A406 HydrophobicContact CE1-CB 4.12Å; Y395-A406 HydrophobicContact CE2-CB 4.48Å; Y395-A406 HydrophobicContact CG-CB 3.59Å; Y395-F409 HydrophobicContact CD2-CD2 4.39Å; Y395-F409 AromaticContact CE2-CD2 3.64Å; Y395-F409 HydrophobicContact CE2-CD2 3.64Å; Y395-F409 HydrophobicContact CE2-CE2 4.03Å; Y395-F409 HydrophobicContact CE2-CG 4.39Å
396	K	83.5	Confident	82.1	Confident	80 Å²	80	82.8 Å²	82.8	35%	0.348	35%	0.35	S	S	.	.			trans	-97.1	115.6	167.4	-175.1	178.9	179	-175.1	0	108.5	R398 E523	K396-R398 HydrophobicContact CG-CG 4.47Å; K396-R398 PolarHBondContact O-N 3.46Å; K396-E523 WeakPolarHBondContact CE-OE1 3.36Å; K396-E523 WeakPolarHBondContact CE-OE2 3.48Å; K396-E523 IonicContact NZ-OE1 3.4Å; K396-E523 PolarHBondContact NZ-OE1 3.17Å; K396-E523 IonicContact NZ-OE2 3.94Å; K396-E523 PolarHBondContact NZ-OE2 3.41Å; K396-E523 VanDerWaalsContact NZ-OE2 3.1Å
397	I	83.6	Confident	82.3	Confident	10 Å²	10	82.7 Å²	82.7	5%	0.051	35%	0.349	C	S	.	.			trans	-78.7	123.6	-178.4	-54.2	-168.9	0	0	0	109.7	Y33 I382 I387 L410	Y33-I397 HydrophobicContact CD1-CG2 3.65Å; Y33-I397 HydrophobicContact CE1-CG2 3.94Å; Y33-I397 HydrophobicContact CG-CG2 4.48Å; I382-I397 HydrophobicContact CB-CD1 4.38Å; I382-I397 HydrophobicContact CG2-CD1 3.3Å; I382-I397 HydrophobicContact CG2-CG1 4.33Å; I387-I397 HydrophobicContact CD1-CD1 3.97Å; I387-I397 HydrophobicContact CD1-CG1 4.32Å; I387-I397 HydrophobicContact CG1-CD1 3.97Å; I387-I397 HydrophobicContact CG1-CG1 4.24Å; I397-L410 HydrophobicContact CD1-CB 4.05Å; I397-L410 HydrophobicContact CD1-CD1 3.44Å; I397-L410 VanDerWaalsContact CD1-CD1 3.44Å; I397-L410 HydrophobicContact CD1-CD2 3.81Å; I397-L410 HydrophobicContact CD1-CG 3.94Å; I397-L410 HydrophobicContact CG2-CD2 4.08Å
398	R	78.6	Confident	82.6	Confident	86 Å²	86	82.4 Å²	82.4	33%	0.325	35%	0.347	S	S	.	.			trans	-124.3	145.1	-179.6	-58.3	-173.3	-157.6	-174	4.7	110.4	K396 G400 R401 T402	K396-R398 HydrophobicContact CG-CG 4.47Å; K396-R398 PolarHBondContact O-N 3.46Å; R398-G400 PolarHBondContact O-N 3.32Å; R398-R401 HydrophobicContact CB-CB 4.19Å; R398-T402 PolarHBondContact N-OG1 3.31Å; R398-T402 PolarHBondContact O-OG1 3.26Å
399	R	80.9	Confident	83	Confident	182 Å²	182	79.1 Å²	79.1	69%	0.687	34%	0.337	S	S	*	.	T	Hydrogen-bonded Turn	trans	-68.2	132	176.2	-167.8	-178.5	178.6	-179.1	-4.5	109.2	K32 R401	K32-R399 HydrophobicContact CG-CG 4.05Å; K32-R399 WeakPolarHBondContact O-CG 3.47Å; R399-R401 PolarHBondContact O-N 2.94Å; R399-R401 VanDerWaalsContact O-N 3.08Å
400	G	79.1	Confident	83.7	Confident	18 Å²	18	73 Å²	73	19%	0.186	31%	0.31	C	S	.	.	T	Hydrogen-bonded Turn	trans	65.5	6.4	175.2	0	0	0	0	0	117.1	K32 Q34 S35 Q36 R398	K32-G400 PolarHBondContact O-N 3.42Å; Q34-G400 CarbonylContact O-C 3.38Å; Q34-G400 VanDerWaalsContact O-C 3.23Å; Q34-G400 VanDerWaalsContact O-CA 3.26Å; Q34-G400 WeakPolarHBondContact O-CA 3.38Å; S35-G400 WeakPolarHBondContact CA-O 3.49Å; Q36-G400 PolarHBondContact N-O 2.85Å; R398-G400 PolarHBondContact O-N 3.32Å
401	R	76.6	Confident	84.8	Confident	97 Å²	97	64.7 Å²	64.7	37%	0.366	27%	0.273	S	S	.	.	T	Hydrogen-bonded Turn	trans	-141.8	13.5	-173.1	-66.5	-90.5	-175.1	101.2	6.2	112.4	R398 R399 E524	R398-R401 HydrophobicContact CB-CB 4.19Å; R399-R401 PolarHBondContact O-N 2.94Å; R399-R401 VanDerWaalsContact O-N 3.08Å; R401-E524 PolarHBondContact NH1-O 3.25Å; R401-E524 PolarHBondContact NH2-O 2.86Å
402	T	85.3	Confident	85.5	Confident	4 Å²	4	55.9 Å²	55.9	3%	0.025	24%	0.243	C	C	.	.	B	Isolated β-bridge	trans	-80.3	126.9	178.1	-58.2	0	0	0	0	109.8	Y33 S35 R398 A406 L407	Y33-T402 WeakPolarHBondContact O-CB 3.47Å; Y33-T402 PolarHBondContact O-N 2.85Å; Y33-T402 PolarHBondContact O-OG1 2.95Å; S35-T402 WeakPolarHBondContact CB-O 3.48Å; S35-T402 PolarHBondContact N-O 3.41Å; R398-T402 PolarHBondContact N-OG1 3.31Å; R398-T402 PolarHBondContact O-OG1 3.26Å; T402-A406 HydrophobicContact CG2-CB 3.6Å; T402-L407 HydrophobicContact CG2-CB 4.27Å
403	R	85.3	Confident	86.2	Confident	149 Å²	149	50.9 Å²	50.9	56%	0.562	22%	0.217	S	C	*	.			trans	-59.6	149.2	176.1	-66.7	-164	168.9	147.6	-0.9	111.4	E38 Q405 A406 L407	E38-R403 WeakPolarHBondContact OE2-CG 3.46Å; E38-R403 IonicContact OE2-NE 3.1Å; E38-R403 PolarHBondContact OE2-NE 3.39Å; R403-Q405 VanDerWaalsContact C-N 3.26Å; R403-Q405 PolarHBondContact O-N 2.85Å; R403-A406 PolarHBondContact O-N 3.02Å; R403-A406 VanDerWaalsContact O-N 3.13Å; R403-L407 WeakPolarHBondContact O-CB 3.2Å; R403-L407 PolarHBondContact O-N 3.33Å
404	P	86.9	Confident	86.8	Confident	18 Å²	18	44 Å²	44	12%	0.117	19%	0.191	C	C	.	.	H	α-helix	trans	-51.1	-41.7	179.3	-30.2	36.8	0	0	0	114.4	E38 L407 L408	E38-P404 WeakPolarHBondContact O-CG 3.2Å; P404-L407 WeakPolarHBondContact O-CB 3.29Å; P404-L407 PolarHBondContact O-N 3.43Å; P404-L408 WeakPolarHBondContact O-CG 3.45Å; P404-L408 PolarHBondContact O-N 3.3Å
405	Q	87.8	Confident	87.4	Confident	20 Å²	20	40.2 Å²	40.2	9%	0.093	17%	0.171	C	C	.	.	H	α-helix	trans	-62.2	-49.4	177.2	-70.4	173.4	1.8	0	0	113.2	Y117 E121 Y395 R403 L407 L408 F409	Y117-Q405 HydrophobicContact CD2-CB 4.03Å; Y117-Q405 HydrophobicContact CD2-CG 4.05Å; Y117-Q405 HydrophobicContact CE2-CB 3.74Å; Y117-Q405 HydrophobicContact CE2-CG 3.85Å; E121-Q405 PolarHBondContact OE2-NE2 3.36Å; E121-Q405 PolarHBondContact OE2-OE1 3.23Å; Y395-Q405 PolarHBondContact OH-OE1 2.93Å; R403-Q405 VanDerWaalsContact C-N 3.26Å; R403-Q405 PolarHBondContact O-N 2.85Å; Q405-L407 PolarHBondContact O-N 2.74Å; Q405-L408 WeakPolarHBondContact O-CB 3.31Å; Q405-L408 PolarHBondContact O-N 2.83Å; Q405-L408 VanDerWaalsContact O-N 3.17Å; Q405-F409 PolarHBondContact O-N 3.46Å
406	A	88.4	Confident	87.9	Confident	4 Å²	4	38.8 Å²	38.8	3%	0.033	17%	0.166	C	C	.	.	H	α-helix	trans	-63.8	-33.7	177.4	0	0	0	0	0	111.6	Y395 T402 R403 L410	Y395-A406 HydrophobicContact CD1-CB 3.64Å; Y395-A406 HydrophobicContact CD2-CB 4.04Å; Y395-A406 HydrophobicContact CE1-CB 4.12Å; Y395-A406 HydrophobicContact CE2-CB 4.48Å; Y395-A406 HydrophobicContact CG-CB 3.59Å; T402-A406 HydrophobicContact CG2-CB 3.6Å; R403-A406 PolarHBondContact O-N 3.02Å; R403-A406 VanDerWaalsContact O-N 3.13Å; A406-L410 VanDerWaalsContact O-CB 3.31Å; A406-L410 WeakPolarHBondContact O-CB 3.28Å; A406-L410 PolarHBondContact O-N 3.49Å
407	L	89.9	Confident	88.5	Confident	2 Å²	2	35 Å²	35	1%	0.01	15%	0.15	C	C	.	.	H	α-helix	trans	-66.3	-41.3	173.9	177.8	69.6	0	0	0	111.7	V30 Q34 T44 A47 T402 R403 P404 Q405 L410 C411	V30-L407 HydrophobicContact CG1-CD1 4.43Å; V30-L407 HydrophobicContact CG1-CD2 3.91Å; Q34-L407 HydrophobicContact CB-CD2 4.34Å; T44-L407 HydrophobicContact CG2-CD2 4.39Å; A47-L407 HydrophobicContact CB-CD2 4.43Å; A47-L407 HydrophobicContact CB-CG 4.34Å; T402-L407 HydrophobicContact CG2-CB 4.27Å; R403-L407 WeakPolarHBondContact O-CB 3.2Å; R403-L407 PolarHBondContact O-N 3.33Å; P404-L407 WeakPolarHBondContact O-CB 3.29Å; P404-L407 PolarHBondContact O-N 3.43Å; Q405-L407 PolarHBondContact O-N 2.74Å; L407-L410 HydrophobicContact CD1-CD2 4.44Å; L407-L410 WeakPolarHBondContact O-CB 3.46Å; L407-L410 PolarHBondContact O-N 3.24Å; L407-C411 PolarHBondContact O-N 3.41Å
408	L	91.6	Very high	89	Confident	1 Å²	1	34.6 Å²	34.6	1%	0.005	15%	0.148	C	C	.	.	H	α-helix	trans	-63.4	-44.2	174.8	-70.1	170	0	0	0	111.6	T46 I113 V116 P404 Q405 L410 C411 M412	T46-L408 HydrophobicContact CG2-CD2 3.75Å; I113-L408 HydrophobicContact CG2-CB 4.34Å; V116-L408 HydrophobicContact CB-CD1 4.34Å; V116-L408 HydrophobicContact CG1-CD1 3.84Å; V116-L408 HydrophobicContact CG1-CD2 4.46Å; P404-L408 WeakPolarHBondContact O-CG 3.45Å; P404-L408 PolarHBondContact O-N 3.3Å; Q405-L408 WeakPolarHBondContact O-CB 3.31Å; Q405-L408 PolarHBondContact O-N 2.83Å; Q405-L408 VanDerWaalsContact O-N 3.17Å; L408-L410 PolarHBondContact O-N 2.99Å; L408-C411 PolarHBondContact O-N 3.3Å; L408-M412 WeakPolarHBondContact O-CB 3.47Å; L408-M412 PolarHBondContact O-N 3.44Å
409	F	91.3	Very high	89.7	Confident	62 Å²	62	30.8 Å²	30.8	27%	0.272	13%	0.134	S	C	.	.	H	α-helix	trans	-61.6	-42.5	173.6	-90.9	-71.8	0	0	0	112.6	Y117 I387 Y395 Q405 C411 M412 I413	Y117-F409 HydrophobicContact CD2-CD2 4.16Å; Y117-F409 AromaticContact CD2-CE2 3.82Å; Y117-F409 HydrophobicContact CD2-CE2 3.82Å; Y117-F409 HydrophobicContact CE1-CE2 4.48Å; Y117-F409 AromaticContact CE2-CD2 3.86Å; Y117-F409 HydrophobicContact CE2-CD2 3.86Å; Y117-F409 AromaticContact CE2-CE2 3.31Å; Y117-F409 HydrophobicContact CE2-CE2 3.31Å; Y117-F409 HydrophobicContact CE2-CZ 4.33Å; Y117-F409 AromaticContact CZ-CE2 3.7Å; I387-F409 HydrophobicContact CD1-CB 4.05Å; Y395-F409 HydrophobicContact CD2-CD2 4.39Å; Y395-F409 AromaticContact CE2-CD2 3.64Å; Y395-F409 HydrophobicContact CE2-CD2 3.64Å; Y395-F409 HydrophobicContact CE2-CE2 4.03Å; Y395-F409 HydrophobicContact CE2-CG 4.39Å; Q405-F409 PolarHBondContact O-N 3.46Å; F409-C411 VanDerWaalsContact C-N 3.35Å; F409-C411 PolarHBondContact O-N 2.95Å; F409-M412 PolarHBondContact O-N 3.39Å; F409-I413 VanDerWaalsContact O-CG1 3.31Å; F409-I413 WeakPolarHBondContact O-CG1 3.4Å; F409-I413 PolarHBondContact O-N 2.85Å
410	L	92	Very high	90.4	Very high	2 Å²	2	22.2 Å²	22.2	1%	0.01	10%	0.102	C	C	.	.	H	α-helix	trans	-58.4	-46.6	174.7	172.7	57.7	0	0	0	111.5	Y29 I382 I387 I397 A406 L407 L408 I413 L414	Y29-L410 HydrophobicContact CE1-CD2 4.5Å; Y29-L410 WeakPolarHBondContact OH-CD1 3.48Å; Y29-L410 WeakPolarHBondContact OH-CD2 3.11Å; Y29-L410 VanDerWaalsContact OH-CG 3.23Å; Y29-L410 WeakPolarHBondContact OH-CG 3.24Å; I382-L410 HydrophobicContact CB-CD1 4.48Å; I382-L410 HydrophobicContact CD1-CD1 3.79Å; I382-L410 HydrophobicContact CG2-CD1 4.05Å; I387-L410 HydrophobicContact CD1-CB 4.46Å; I397-L410 HydrophobicContact CD1-CB 4.05Å; I397-L410 HydrophobicContact CD1-CD1 3.44Å; I397-L410 VanDerWaalsContact CD1-CD1 3.44Å; I397-L410 HydrophobicContact CD1-CD2 3.81Å; I397-L410 HydrophobicContact CD1-CG 3.94Å; I397-L410 HydrophobicContact CG2-CD2 4.08Å; A406-L410 VanDerWaalsContact O-CB 3.31Å; A406-L410 WeakPolarHBondContact O-CB 3.28Å; A406-L410 PolarHBondContact O-N 3.49Å; L407-L410 HydrophobicContact CD1-CD2 4.44Å; L407-L410 WeakPolarHBondContact O-CB 3.46Å; L407-L410 PolarHBondContact O-N 3.24Å; L408-L410 PolarHBondContact O-N 2.99Å; L410-I413 PolarHBondContact O-N 3.39Å; L410-L414 HydrophobicContact CD1-CD1 4.06Å; L410-L414 HydrophobicContact CD1-CG 4.26Å; L410-L414 HydrophobicContact CG-CD1 4.32Å; L410-L414 WeakPolarHBondContact O-CB 3.31Å; L410-L414 WeakPolarHBondContact O-CG 3.27Å; L410-L414 PolarHBondContact O-N 3.08Å
411	C	92.7	Very high	91	Very high	0 Å²	0	21.4 Å²	21.4	0%	0	9%	0.093	C	C	.	.	H	α-helix	trans	-64.8	-39.9	176.9	-77.8	0	0	0	0	112.4	A47 L407 L408 F409 L414 L415	A47-C411 HydrophobicContact CB-CB 4.33Å; A47-C411 VanDerWaalsContact CB-SG 3.54Å; L407-C411 PolarHBondContact O-N 3.41Å; L408-C411 PolarHBondContact O-N 3.3Å; F409-C411 VanDerWaalsContact C-N 3.35Å; F409-C411 PolarHBondContact O-N 2.95Å; C411-L414 PolarHBondContact O-N 2.9Å; C411-L415 VanDerWaalsContact O-CB 3.28Å; C411-L415 WeakPolarHBondContact O-CB 3.19Å; C411-L415 PolarHBondContact O-N 3.17Å
412	M	93.6	Very high	91.7	Very high	48 Å²	48	16.9 Å²	16.9	24%	0.236	8%	0.076	C	C	.	.	H	α-helix	trans	-61.3	-48.3	174.3	-178.5	-175.3	161.3	0	0	111.5	V109 I113 L408 F409 L414 L415 L416	V109-M412 HydrophobicContact CG1-CE 4.4Å; I113-M412 HydrophobicContact CD1-CB 4.34Å; L408-M412 WeakPolarHBondContact O-CB 3.47Å; L408-M412 PolarHBondContact O-N 3.44Å; F409-M412 PolarHBondContact O-N 3.39Å; M412-L414 VanDerWaalsContact C-N 3.35Å; M412-L414 PolarHBondContact O-N 3.41Å; M412-L415 PolarHBondContact O-N 2.84Å; M412-L416 HydrophobicContact CE-CD1 4.14Å; M412-L416 HydrophobicContact CG-CD1 4.39Å; M412-L416 WeakPolarHBondContact O-CG 3.45Å; M412-L416 PolarHBondContact O-N 3.29Å
413	I	94.3	Very high	91.9	Very high	23 Å²	23	16.8 Å²	16.8	12%	0.118	8%	0.075	C	C	.	.	H	α-helix	trans	-60.5	-45.5	177.8	-69	168.9	0	0	0	110.5	A204 Y208 I382 I387 F409 L410 L416 I417	A204-I413 HydrophobicContact CB-CG2 4.25Å; Y208-I413 HydrophobicContact CD2-CG2 4.1Å; Y208-I413 HydrophobicContact CE2-CG2 4.18Å; I382-I413 HydrophobicContact CD1-CG2 3.87Å; I387-I413 HydrophobicContact CD1-CD1 4.15Å; I387-I413 HydrophobicContact CG1-CD1 4.14Å; I387-I413 HydrophobicContact CG2-CD1 3.88Å; F409-I413 VanDerWaalsContact O-CG1 3.31Å; F409-I413 WeakPolarHBondContact O-CG1 3.4Å; F409-I413 PolarHBondContact O-N 2.85Å; L410-I413 PolarHBondContact O-N 3.39Å; I413-L416 PolarHBondContact O-N 3.14Å; I413-I417 HydrophobicContact CG2-CD1 3.8Å; I413-I417 HydrophobicContact CG2-CG1 4.44Å; I413-I417 VanDerWaalsContact O-CG1 3.3Å; I413-I417 WeakPolarHBondContact O-CG1 3.36Å; I413-I417 PolarHBondContact O-N 3.5Å
414	L	94	Very high	92.1	Very high	1 Å²	1	9.7 Å²	9.7	1%	0.005	5%	0.049	C	C	.	.	H	α-helix	trans	-64.3	-40.4	177.7	-76.5	175.4	0	0	0	112.6	Y29 L51 M379 I382 L410 C411 M412 L416 I417 V418	Y29-L414 HydrophobicContact CE1-CD1 3.64Å; Y29-L414 HydrophobicContact CE2-CD1 4.36Å; Y29-L414 VanDerWaalsContact CZ-CD1 3.44Å; Y29-L414 WeakPolarHBondContact OH-CD1 3.35Å; L51-L414 HydrophobicContact CD1-CB 4.11Å; M379-L414 HydrophobicContact CG-CD1 4.13Å; M379-L414 HydrophobicContact CG-CD2 3.97Å; I382-L414 HydrophobicContact CD1-CD2 3.92Å; I382-L414 HydrophobicContact CD1-CG 4.15Å; L410-L414 HydrophobicContact CD1-CD1 4.06Å; L410-L414 HydrophobicContact CD1-CG 4.26Å; L410-L414 HydrophobicContact CG-CD1 4.32Å; L410-L414 WeakPolarHBondContact O-CB 3.31Å; L410-L414 WeakPolarHBondContact O-CG 3.27Å; L410-L414 PolarHBondContact O-N 3.08Å; C411-L414 PolarHBondContact O-N 2.9Å; M412-L414 VanDerWaalsContact C-N 3.35Å; M412-L414 PolarHBondContact O-N 3.41Å; L414-L416 VanDerWaalsContact C-N 3.32Å; L414-L416 PolarHBondContact O-N 3.43Å; L414-I417 PolarHBondContact O-N 2.98Å; L414-V418 WeakPolarHBondContact O-CB 3.33Å; L414-V418 VanDerWaalsContact O-CG2 3.22Å; L414-V418 WeakPolarHBondContact O-CG2 3.32Å; L414-V418 PolarHBondContact O-N 2.82Å
415	L	95.5	Very high	92.3	Very high	1 Å²	1	9.1 Å²	9.1	1%	0.005	5%	0.045	C	C	.	.	H	α-helix	trans	-57.8	-46	173.9	171.8	161.1	0	0	0	110.9	A54 I105 V109 C411 M412 V418 L419	A54-L415 HydrophobicContact CB-CB 4.15Å; A54-L415 HydrophobicContact CB-CD1 4.39Å; A54-L415 HydrophobicContact CB-CG 3.86Å; I105-L415 HydrophobicContact CG2-CD1 4.48Å; I105-L415 HydrophobicContact CG2-CD2 3.91Å; V109-L415 HydrophobicContact CG2-CD1 4.2Å; V109-L415 HydrophobicContact CG2-CD2 3.59Å; C411-L415 VanDerWaalsContact O-CB 3.28Å; C411-L415 WeakPolarHBondContact O-CB 3.19Å; C411-L415 PolarHBondContact O-N 3.17Å; M412-L415 PolarHBondContact O-N 2.84Å; L415-V418 PolarHBondContact O-N 2.83Å; L415-L419 WeakPolarHBondContact O-CB 3.05Å; L415-L419 PolarHBondContact O-N 3.33Å
416	L	95.6	Very high	92.3	Very high	7 Å²	7	8.8 Å²	8.8	4%	0.037	4%	0.043	C	C	.	.	H	α-helix	trans	-65.4	-39.6	178.5	-65.1	173.2	0	0	0	112	L197 I200 G201 M412 I413 L414 L419 H420	L197-L416 HydrophobicContact CB-CD2 3.99Å; L197-L416 HydrophobicContact CD2-CD2 3.97Å; L197-L416 HydrophobicContact CG-CD2 4.4Å; I200-L416 HydrophobicContact CG2-CD1 3.9Å; G201-L416 WeakPolarHBondContact CA-O 3.26Å; M412-L416 HydrophobicContact CE-CD1 4.14Å; M412-L416 HydrophobicContact CG-CD1 4.39Å; M412-L416 WeakPolarHBondContact O-CG 3.45Å; M412-L416 PolarHBondContact O-N 3.29Å; I413-L416 PolarHBondContact O-N 3.14Å; L414-L416 VanDerWaalsContact C-N 3.32Å; L414-L416 PolarHBondContact O-N 3.43Å; L416-L419 PolarHBondContact O-N 2.96Å; L416-H420 PolarHBondContact O-N 2.89Å
417	I	95.9	Very high	92.2	Very high	1 Å²	1	8.6 Å²	8.6	1%	0.005	4%	0.041	C	C	.	.	H	α-helix	trans	-64.7	-43	174.8	-69.6	170.4	0	0	0	111	A204 S378 I382 I413 L414 L419 H420 T421	A204-I417 HydrophobicContact CB-CD1 4.14Å; A204-I417 HydrophobicContact CB-CG1 3.78Å; S378-I417 WeakPolarHBondContact OG-CG2 3.4Å; I382-I417 HydrophobicContact CD1-CD1 4.44Å; I413-I417 HydrophobicContact CG2-CD1 3.8Å; I413-I417 HydrophobicContact CG2-CG1 4.44Å; I413-I417 VanDerWaalsContact O-CG1 3.3Å; I413-I417 WeakPolarHBondContact O-CG1 3.36Å; I413-I417 PolarHBondContact O-N 3.5Å; L414-I417 PolarHBondContact O-N 2.98Å; I417-L419 VanDerWaalsContact C-N 3.33Å; I417-L419 PolarHBondContact O-N 3.01Å; I417-H420 CarbonylContact O-C 3.6Å; I417-H420 PolarHBondContact O-N 2.9Å; I417-T421 WeakPolarHBondContact O-CB 3.19Å; I417-T421 PolarHBondContact O-N 3.4Å; I417-T421 PolarHBondContact O-OG1 3Å
418	V	94.5	Very high	92.1	Very high	1 Å²	1	8.7 Å²	8.7	1%	0.006	4%	0.042	C	C	.	.	H	α-helix	trans	-61.7	-43.7	177.5	167.6	0	0	0	0	110.3	A54 L55 S58 I375 L414 L415 H420 T421 S422	A54-V418 HydrophobicContact CB-CB 4.29Å; A54-V418 HydrophobicContact CB-CG1 3.94Å; A54-V418 WeakPolarHBondContact O-CG1 3.49Å; L55-V418 HydrophobicContact CD2-CG1 4.22Å; L55-V418 HydrophobicContact CD2-CG2 4.1Å; S58-V418 WeakPolarHBondContact OG-CG1 3.2Å; S58-V418 PolarHBondContact OG-O 3.44Å; I375-V418 HydrophobicContact CD1-CG2 4.02Å; I375-V418 HydrophobicContact CG1-CG2 3.76Å; L414-V418 WeakPolarHBondContact O-CB 3.33Å; L414-V418 VanDerWaalsContact O-CG2 3.22Å; L414-V418 WeakPolarHBondContact O-CG2 3.32Å; L414-V418 PolarHBondContact O-N 2.82Å; L415-V418 PolarHBondContact O-N 2.83Å; V418-H420 PolarHBondContact O-N 2.74Å; V418-T421 WeakPolarHBondContact O-CB 3.39Å; V418-T421 PolarHBondContact O-N 3.26Å; V418-T421 VanDerWaalsContact O-N 3.11Å; V418-S422 PolarHBondContact O-N 2.9Å
419	L	93.4	Very high	91.9	Very high	5 Å²	5	8.7 Å²	8.7	3%	0.026	4%	0.042	C	C	.	.	H	α-helix	trans	-60.2	-45.1	174.6	-166.1	71.5	0	0	0	111.6	Y102 I105 I194 L197 T198 L415 L416 I417 T421 S422	Y102-L419 HydrophobicContact CD1-CD1 4.23Å; Y102-L419 HydrophobicContact CE1-CD1 3.77Å; I105-L419 HydrophobicContact CD1-CD1 4.08Å; I194-L419 HydrophobicContact CG2-CD1 4.25Å; I194-L419 HydrophobicContact CG2-CD2 4.24Å; I194-L419 HydrophobicContact CG2-CG 4.49Å; L197-L419 HydrophobicContact CB-CD2 3.78Å; T198-L419 HydrophobicContact CG2-CB 4.17Å; T198-L419 HydrophobicContact CG2-CD2 3.66Å; T198-L419 HydrophobicContact CG2-CG 3.44Å; T198-L419 VanDerWaalsContact CG2-CG 3.44Å; L415-L419 WeakPolarHBondContact O-CB 3.05Å; L415-L419 PolarHBondContact O-N 3.33Å; L416-L419 PolarHBondContact O-N 2.96Å; I417-L419 VanDerWaalsContact C-N 3.33Å; I417-L419 PolarHBondContact O-N 3.01Å; L419-T421 VanDerWaalsContact C-N 3.31Å; L419-T421 PolarHBondContact O-N 3.33Å; L419-S422 WeakPolarHBondContact O-CB 3.32Å; L419-S422 PolarHBondContact O-N 3.41Å
420	H	94.4	Very high	91.5	Very high	3 Å²	3	6.2 Å²	6.2	1%	0.014	3%	0.032	C	C	.	.	H	α-helix	trans	-66.1	-31.6	174.2	175.9	67.5	0	0	0	112.8	L416 I417 V418 S422 Y423 M424	L416-H420 PolarHBondContact O-N 2.89Å; I417-H420 CarbonylContact O-C 3.6Å; I417-H420 PolarHBondContact O-N 2.9Å; V418-H420 PolarHBondContact O-N 2.74Å; H420-S422 PolarHBondContact O-N 3.19Å; H420-Y423 AromaticContact CE1-CD1 3.88Å; H420-Y423 WeakPolarHBondContact O-CA 3.45Å; H420-Y423 WeakPolarHBondContact O-CB 3.31Å; H420-Y423 PolarHBondContact O-N 2.78Å; H420-M424 PolarHBondContact O-N 3.23Å
421	T	92.8	Very high	91	Very high	0 Å²	0	7.2 Å²	7.2	0%	0	4%	0.036	C	C	.	.	H	α-helix	trans	-61.2	-36.2	179	-59.6	0	0	0	0	111.1	I371 F374 I417 V418 L419 Y423 M424 I425	I371-T421 HydrophobicContact CG1-CG2 4.47Å; F374-T421 HydrophobicContact CB-CG2 3.85Å; F374-T421 HydrophobicContact CD2-CG2 3.59Å; F374-T421 HydrophobicContact CE2-CG2 4.46Å; F374-T421 HydrophobicContact CG-CG2 3.97Å; I417-T421 WeakPolarHBondContact O-CB 3.19Å; I417-T421 PolarHBondContact O-N 3.4Å; I417-T421 PolarHBondContact O-OG1 3Å; V418-T421 WeakPolarHBondContact O-CB 3.39Å; V418-T421 PolarHBondContact O-N 3.26Å; V418-T421 VanDerWaalsContact O-N 3.11Å; L419-T421 VanDerWaalsContact C-N 3.31Å; L419-T421 PolarHBondContact O-N 3.33Å; T421-Y423 VanDerWaalsContact C-N 3.28Å; T421-Y423 PolarHBondContact O-N 3.48Å; T421-M424 PolarHBondContact O-N 3.35Å; T421-M424 VanDerWaalsContact O-N 3.13Å; T421-I425 HydrophobicContact CG2-CD1 4.17Å; T421-I425 HydrophobicContact CG2-CG1 4.48Å; T421-I425 WeakPolarHBondContact O-CG1 3.35Å; T421-I425 PolarHBondContact O-N 3.48Å
422	S	89.9	Confident	90.7	Very high	3 Å²	3	7.4 Å²	7.4	2%	0.021	4%	0.037	C	C	.	.	H	α-helix	trans	-57.5	-40.1	172.3	-65.5	0	0	0	0	112.4	S58 V418 L419 H420	S58-S422 PolarHBondContact OG-OG 3.25Å; V418-S422 PolarHBondContact O-N 2.9Å; L419-S422 WeakPolarHBondContact O-CB 3.32Å; L419-S422 PolarHBondContact O-N 3.41Å; H420-S422 PolarHBondContact O-N 3.19Å
423	Y	89.4	Confident	90.4	Very high	1 Å²	1	5.3 Å²	5.3	0%	0.004	3%	0.027	C	C	.	.	H	α-helix	trans	-69.7	-42.5	172	172.9	-86.4	0	0	0	112.4	H420 T421 I425 Y426 S427 L481 H482 Y491	H420-Y423 AromaticContact CE1-CD1 3.88Å; H420-Y423 WeakPolarHBondContact O-CA 3.45Å; H420-Y423 WeakPolarHBondContact O-CB 3.31Å; H420-Y423 PolarHBondContact O-N 2.78Å; T421-Y423 VanDerWaalsContact C-N 3.28Å; T421-Y423 PolarHBondContact O-N 3.48Å; Y423-I425 PolarHBondContact O-N 2.79Å; Y423-Y426 VanDerWaalsContact O-CB 3.3Å; Y423-Y426 WeakPolarHBondContact O-CB 3.43Å; Y423-Y426 PolarHBondContact O-N 2.86Å; Y423-S427 VanDerWaalsContact CE1-OG 3.26Å; Y423-S427 WeakPolarHBondContact CE1-OG 3.27Å; Y423-S427 PolarHBondContact O-N 3.5Å; Y423-S427 VanDerWaalsContact O-N 3.15Å; Y423-S427 PolarHBondContact OH-OG 3.03Å; Y423-L481 HydrophobicContact CD2-CB 4.49Å; Y423-H482 AromaticContact CD2-NE2 3.76Å; Y423-H482 AromaticContact CE2-CE1 3.29Å; Y423-H482 WeakPolarHBondContact CE2-CE1 3.44Å; Y423-H482 AromaticContact CE2-NE2 3.42Å; Y423-H482 WeakPolarHBondContact CE2-NE2 3.43Å; Y423-Y491 HydrophobicContact CD1-CD1 4.4Å; Y423-Y491 HydrophobicContact CD1-CD2 4.37Å; Y423-Y491 HydrophobicContact CD1-CG 4.09Å; Y423-Y491 AromaticContact CD2-CD2 3.61Å; Y423-Y491 HydrophobicContact CD2-CD2 3.61Å; Y423-Y491 AromaticContact CD2-CE2 3.89Å; Y423-Y491 HydrophobicContact CD2-CE2 3.89Å; Y423-Y491 HydrophobicContact CD2-CG 4.17Å; Y423-Y491 HydrophobicContact CE1-CD1 4.36Å; Y423-Y491 HydrophobicContact CE1-CD2 4.06Å; Y423-Y491 AromaticContact CE1-CG 3.7Å; Y423-Y491 HydrophobicContact CE1-CG 3.7Å; Y423-Y491 AromaticContact CE2-CD2 3.15Å; Y423-Y491 HydrophobicContact CE2-CD2 3.15Å; Y423-Y491 AromaticContact CE2-CE2 3.86Å; Y423-Y491 HydrophobicContact CE2-CE2 3.86Å; Y423-Y491 AromaticContact CE2-CG 3.71Å; Y423-Y491 HydrophobicContact CE2-CG 3.71Å; Y423-Y491 HydrophobicContact CG-CD2 4.2Å; Y423-Y491 HydrophobicContact CG-CE2 4.48Å; Y423-Y491 HydrophobicContact CG-CG 4.35Å; Y423-Y491 AromaticContact CZ-CD2 3.46Å; Y423-Y491 VanDerWaalsContact CZ-CD2 3.46Å; Y423-Y491 AromaticContact CZ-CG 3.5Å; Y423-Y491 VanDerWaalsContact CZ-CG 3.5Å; Y423-Y491 WeakPolarHBondContact OH-CB 3.22Å
424	M	91.3	Very high	89.9	Confident	1 Å²	1	4.5 Å²	4.5	1%	0.005	2%	0.023	C	C	.	.	H	α-helix	trans	-62.4	-33.4	-178.2	-173.5	162.3	48.5	0	0	111.9	F374 H420 T421 Y426 S427 L428 F498	F374-M424 HydrophobicContact CD1-CE 3.32Å; F374-M424 HydrophobicContact CD2-CE 3.99Å; F374-M424 HydrophobicContact CE1-CE 3.17Å; F374-M424 HydrophobicContact CE1-SD 3.81Å; F374-M424 HydrophobicContact CE2-CE 3.86Å; F374-M424 HydrophobicContact CG-CE 3.74Å; F374-M424 HydrophobicContact CZ-CE 3.47Å; F374-M424 VanDerWaalsContact CZ-CE 3.47Å; F374-M424 HydrophobicContact CZ-CG 4.29Å; F374-M424 HydrophobicContact CZ-SD 3.91Å; H420-M424 PolarHBondContact O-N 3.23Å; T421-M424 PolarHBondContact O-N 3.35Å; T421-M424 VanDerWaalsContact O-N 3.13Å; M424-Y426 VanDerWaalsContact C-N 3.32Å; M424-Y426 PolarHBondContact O-N 3.32Å; M424-S427 CarbonylContact O-C 3.55Å; M424-S427 WeakPolarHBondContact O-CB 3.23Å; M424-S427 PolarHBondContact O-N 3.11Å; M424-S427 VanDerWaalsContact O-N 3.11Å; M424-L428 WeakPolarHBondContact O-CG 3.44Å; M424-L428 PolarHBondContact O-N 3.2Å; M424-F498 HydrophobicContact SD-CE1 4.32Å; M424-F498 HydrophobicContact SD-CE2 4.17Å; M424-F498 HydrophobicContact SD-CZ 3.96Å
425	I	90.3	Very high	89.5	Confident	6 Å²	6	5.1 Å²	5.1	3%	0.031	3%	0.025	C	C	.	.	H	α-helix	trans	-61.5	-39.2	173.1	-69.3	163.5	0	0	0	111.5	L61 I367 I370 I371 T421 Y423 S427 L428 A429 V433	L61-I425 HydrophobicContact CD2-CB 4.13Å; L61-I425 HydrophobicContact CD2-CD1 3.8Å; L61-I425 HydrophobicContact CD2-CG2 3.9Å; I367-I425 HydrophobicContact CG2-CD1 4.34Å; I370-I425 HydrophobicContact CG2-CG1 4.38Å; I371-I425 HydrophobicContact CD1-CD1 4.03Å; I371-I425 HydrophobicContact CG1-CD1 3.49Å; I371-I425 VanDerWaalsContact CG1-CD1 3.49Å; T421-I425 HydrophobicContact CG2-CD1 4.17Å; T421-I425 HydrophobicContact CG2-CG1 4.48Å; T421-I425 WeakPolarHBondContact O-CG1 3.35Å; T421-I425 PolarHBondContact O-N 3.48Å; Y423-I425 PolarHBondContact O-N 2.79Å; I425-S427 VanDerWaalsContact C-N 3.35Å; I425-S427 PolarHBondContact O-N 3.3Å; I425-L428 WeakPolarHBondContact O-CB 3.47Å; I425-L428 PolarHBondContact O-N 3.46Å; I425-A429 PolarHBondContact O-N 3.1Å; I425-V433 HydrophobicContact CG2-CG2 3.66Å
426	Y	87.1	Confident	89	Confident	13 Å²	13	5.6 Å²	5.6	5%	0.051	3%	0.03	C	C	.	.	H	α-helix	trans	-62.3	-41.8	171.8	178.9	-91.5	0	0	0	111.9	Y423 M424 L428 A429 P430 V433 M434 Y478 H482	Y423-Y426 VanDerWaalsContact O-CB 3.3Å; Y423-Y426 WeakPolarHBondContact O-CB 3.43Å; Y423-Y426 PolarHBondContact O-N 2.86Å; M424-Y426 VanDerWaalsContact C-N 3.32Å; M424-Y426 PolarHBondContact O-N 3.32Å; Y426-L428 VanDerWaalsContact C-N 3.25Å; Y426-L428 PolarHBondContact O-N 2.93Å; Y426-A429 CarbonylContact O-C 3.57Å; Y426-A429 PolarHBondContact O-N 2.96Å; Y426-P430 HydrophobicContact CE1-CB 4.21Å; Y426-P430 HydrophobicContact CE2-CB 4.31Å; Y426-P430 WeakPolarHBondContact O-CA 3.39Å; Y426-P430 WeakPolarHBondContact O-CB 3.31Å; Y426-P430 WeakPolarHBondContact O-CD 3.06Å; Y426-V433 HydrophobicContact CD2-CB 4.21Å; Y426-V433 HydrophobicContact CD2-CG1 4.06Å; Y426-M434 HydrophobicContact CE2-CB 4.07Å; Y426-M434 HydrophobicContact CE2-SD 4.44Å; Y426-Y478 AromaticContact CD2-CD2 3.94Å; Y426-Y478 HydrophobicContact CD2-CD2 3.94Å; Y426-Y478 HydrophobicContact CE1-CE2 4.26Å; Y426-Y478 AromaticContact CE2-CD2 3.31Å; Y426-Y478 HydrophobicContact CE2-CD2 3.31Å; Y426-Y478 AromaticContact CE2-CE2 3.59Å; Y426-Y478 HydrophobicContact CE2-CE2 3.59Å; Y426-Y478 HydrophobicContact CE2-CG 4.37Å; Y426-Y478 AromaticContact CZ-CD2 3.67Å; Y426-Y478 AromaticContact CZ-CE2 3.43Å; Y426-Y478 VanDerWaalsContact CZ-CE2 3.43Å; Y426-Y478 WeakPolarHBondContact OH-CE2 3.4Å; Y426-H482 AromaticContact CD1-CE1 3.59Å; Y426-H482 AromaticContact CD1-NE2 3.16Å; Y426-H482 WeakPolarHBondContact CD1-NE2 3.48Å; Y426-H482 AromaticContact CE1-CE1 3.48Å; Y426-H482 VanDerWaalsContact CE1-CE1 3.48Å; Y426-H482 WeakPolarHBondContact CE1-CE1 3.3Å; Y426-H482 AromaticContact CE1-NE2 3.38Å; Y426-H482 WeakPolarHBondContact CE1-NE2 3.43Å; Y426-H482 AromaticContact CG-NE2 3.67Å
427	S	87.5	Confident	88.5	Confident	0 Å²	0	7.6 Å²	7.6	0%	0	5%	0.045	C	C	.	.	H	α-helix	trans	-65.9	-29.2	175.4	-68.2	0	0	0	0	112.9	S323 Y423 M424 I425 N495	S323-S427 WeakPolarHBondContact CB-O 3.35Å; S323-S427 PolarHBondContact OG-O 3.32Å; Y423-S427 VanDerWaalsContact CE1-OG 3.26Å; Y423-S427 WeakPolarHBondContact CE1-OG 3.27Å; Y423-S427 PolarHBondContact O-N 3.5Å; Y423-S427 VanDerWaalsContact O-N 3.15Å; Y423-S427 PolarHBondContact OH-OG 3.03Å; M424-S427 CarbonylContact O-C 3.55Å; M424-S427 WeakPolarHBondContact O-CB 3.23Å; M424-S427 PolarHBondContact O-N 3.11Å; M424-S427 VanDerWaalsContact O-N 3.11Å; I425-S427 VanDerWaalsContact C-N 3.35Å; I425-S427 PolarHBondContact O-N 3.3Å; S427-N495 WeakPolarHBondContact CB-ND2 3Å; S427-N495 PolarHBondContact OG-ND2 2.92Å; S427-N495 VanDerWaalsContact OG-ND2 3.09Å
428	L	88.3	Confident	88	Confident	4 Å²	4	7.8 Å²	7.8	2%	0.021	5%	0.046	C	C	.	.	H	α-helix	trans	-74.5	-36.9	177.2	-77	170.6	0	0	0	113.6	F316 L320 N347 L349 I370 F374 M424 I425 Y426	F316-L428 HydrophobicContact CB-CD2 4.21Å; F316-L428 HydrophobicContact CD1-CD1 3.85Å; F316-L428 HydrophobicContact CD1-CD2 3.8Å; F316-L428 HydrophobicContact CE1-CD1 4.12Å; F316-L428 HydrophobicContact CG-CD2 4.42Å; L320-L428 HydrophobicContact CD1-CD2 4.3Å; L320-L428 HydrophobicContact CD2-CD2 3.65Å; L320-L428 HydrophobicContact CD2-CG 3.84Å; L320-L428 HydrophobicContact CG-CD2 3.5Å; L320-L428 HydrophobicContact CG-CG 4.23Å; N347-L428 PolarHBondContact ND2-O 3.21Å; L349-L428 HydrophobicContact CD1-CB 4.18Å; L349-L428 HydrophobicContact CD1-CD1 4.49Å; L349-L428 HydrophobicContact CD1-CD2 3.89Å; L349-L428 HydrophobicContact CD1-CG 4.44Å; I370-L428 HydrophobicContact CG2-CD1 4.39Å; F374-L428 HydrophobicContact CE2-CD1 3.82Å; F374-L428 HydrophobicContact CZ-CD1 3.92Å; M424-L428 WeakPolarHBondContact O-CG 3.44Å; M424-L428 PolarHBondContact O-N 3.2Å; I425-L428 WeakPolarHBondContact O-CB 3.47Å; I425-L428 PolarHBondContact O-N 3.46Å; Y426-L428 VanDerWaalsContact C-N 3.25Å; Y426-L428 PolarHBondContact O-N 2.93Å
429	A	86.4	Confident	87.7	Confident	1 Å²	1	9.1 Å²	9.1	1%	0.008	5%	0.053	C	C	.	.	S	Bend	trans	-148.7	71.7	-177.8	0	0	0	0	0	110.9	N350 L353 I425 Y426 Q431 Y432 V433	N350-A429 HydrophobicContact CB-CB 4.38Å; L353-A429 HydrophobicContact CD1-CB 3.64Å; I425-A429 PolarHBondContact O-N 3.1Å; Y426-A429 CarbonylContact O-C 3.57Å; Y426-A429 PolarHBondContact O-N 2.96Å; A429-Q431 PolarHBondContact O-N 3.42Å; A429-Y432 PolarHBondContact O-N 2.89Å; A429-V433 HydrophobicContact CB-CG2 4.48Å; A429-V433 WeakPolarHBondContact O-CB 3.26Å; A429-V433 VanDerWaalsContact O-CG2 3.25Å; A429-V433 WeakPolarHBondContact O-CG2 3.44Å; A429-V433 PolarHBondContact O-N 3.18Å
430	P	83.2	Confident	87.4	Confident	10 Å²	10	9.3 Å²	9.3	7%	0.065	5%	0.053	C	C	.	.	H	α-helix	trans	-61.8	-41.8	-167.8	21.4	-32.4	0	0	0	113.1	Y426 M434	Y426-P430 HydrophobicContact CE1-CB 4.21Å; Y426-P430 HydrophobicContact CE2-CB 4.31Å; Y426-P430 WeakPolarHBondContact O-CA 3.39Å; Y426-P430 WeakPolarHBondContact O-CB 3.31Å; Y426-P430 WeakPolarHBondContact O-CD 3.06Å; P430-M434 WeakPolarHBondContact O-CB 3.36Å; P430-M434 PolarHBondContact O-N 2.91Å
431	Q	81.3	Confident	87	Confident	23 Å²	23	11.5 Å²	11.5	11%	0.107	7%	0.065	C	C	.	.	H	α-helix	trans	-67.4	-47.5	-178.5	-64.9	-66.9	-20.6	0	0	111.7	T343 N350 A429 V433 M434 Y435 C463	T343-Q431 HydrophobicContact CG2-CG 3.52Å; N350-Q431 PolarHBondContact OD1-N 3.02Å; A429-Q431 PolarHBondContact O-N 3.42Å; Q431-V433 PolarHBondContact O-N 2.8Å; Q431-M434 PolarHBondContact O-N 3.34Å; Q431-Y435 PolarHBondContact O-N 2.97Å; Q431-C463 PolarHBondContact OE1-O 2.92Å
432	Y	85.8	Confident	86.5	Confident	3 Å²	3	14.3 Å²	14.3	1%	0.012	8%	0.079	C	C	.	.	H	α-helix	trans	-64.9	-39.7	179.4	174.6	-89.8	0	0	0	112.1	I65 N350 L353 P354 Q357 D363 I367 A429 G436	I65-Y432 HydrophobicContact CD1-CE1 4.08Å; I65-Y432 HydrophobicContact CG2-CE1 3.89Å; I65-Y432 HydrophobicContact CG2-CE2 4.49Å; N350-Y432 PolarHBondContact OD1-N 3.46Å; L353-Y432 HydrophobicContact CB-CD1 3.76Å; L353-Y432 HydrophobicContact CB-CD2 3.72Å; L353-Y432 HydrophobicContact CB-CE1 3.95Å; L353-Y432 HydrophobicContact CB-CE2 3.86Å; L353-Y432 HydrophobicContact CB-CG 3.65Å; L353-Y432 HydrophobicContact CD1-CD1 3.77Å; L353-Y432 HydrophobicContact CD1-CE1 4.2Å; L353-Y432 HydrophobicContact CD1-CG 4.29Å; L353-Y432 HydrophobicContact CD2-CE1 4.22Å; L353-Y432 HydrophobicContact CG-CD1 4.25Å; L353-Y432 HydrophobicContact CG-CE1 4.36Å; P354-Y432 HydrophobicContact CB-CD2 4.4Å; P354-Y432 HydrophobicContact CG-CD2 3.84Å; Q357-Y432 HydrophobicContact CB-CE2 4.48Å; D363-Y432 WeakPolarHBondContact CB-OH 3.42Å; D363-Y432 PolarHBondContact OD2-OH 3.33Å; I367-Y432 HydrophobicContact CD1-CE1 3.64Å; A429-Y432 PolarHBondContact O-N 2.89Å; Y432-G436 WeakPolarHBondContact O-CA 2.99Å; Y432-G436 PolarHBondContact O-N 3.37Å
433	V	86.7	Confident	85.9	Confident	4 Å²	4	20.6 Å²	20.6	2%	0.024	11%	0.108	C	C	.	.	H	α-helix	trans	-74.7	-30.5	-179.6	177.6	0	0	0	0	111.9	L61 I65 I425 Y426 A429 Q431 T475	L61-V433 HydrophobicContact CD1-CG1 4.13Å; I65-V433 HydrophobicContact CD1-CB 4.4Å; I65-V433 HydrophobicContact CD1-CG1 4.25Å; I65-V433 HydrophobicContact CD1-CG2 4.26Å; I425-V433 HydrophobicContact CG2-CG2 3.66Å; Y426-V433 HydrophobicContact CD2-CB 4.21Å; Y426-V433 HydrophobicContact CD2-CG1 4.06Å; A429-V433 HydrophobicContact CB-CG2 4.48Å; A429-V433 WeakPolarHBondContact O-CB 3.26Å; A429-V433 VanDerWaalsContact O-CG2 3.25Å; A429-V433 WeakPolarHBondContact O-CG2 3.44Å; A429-V433 PolarHBondContact O-N 3.18Å; Q431-V433 PolarHBondContact O-N 2.8Å; V433-T475 WeakPolarHBondContact O-CG2 3.29Å; V433-T475 PolarHBondContact O-OG1 2.86Å
434	M	85.6	Confident	84.6	Confident	7 Å²	7	21.9 Å²	21.9	3%	0.034	12%	0.117	C	C	.	.	H	α-helix	trans	-77.3	-47.1	-179.9	-167.1	168.5	167.5	0	0	112.5	Y426 P430 Q431 V474 T475 Y478	Y426-M434 HydrophobicContact CE2-CB 4.07Å; Y426-M434 HydrophobicContact CE2-SD 4.44Å; P430-M434 WeakPolarHBondContact O-CB 3.36Å; P430-M434 PolarHBondContact O-N 2.91Å; Q431-M434 PolarHBondContact O-N 3.34Å; M434-V474 HydrophobicContact CE-CG1 3.79Å; M434-V474 HydrophobicContact CG-CG1 4.12Å; M434-V474 WeakPolarHBondContact O-CA 3.43Å; M434-T475 PolarHBondContact O-N 3.31Å; M434-Y478 HydrophobicContact CE-CD1 4.4Å; M434-Y478 HydrophobicContact CE-CE1 3.84Å; M434-Y478 HydrophobicContact CG-CD1 4.45Å; M434-Y478 HydrophobicContact CG-CG 4.38Å; M434-Y478 HydrophobicContact SD-CE1 4.4Å; M434-Y478 HydrophobicContact SD-CE2 4.3Å
435	Y	84.3	Confident	82.9	Confident	14 Å²	14	28.3 Å²	28.3	6%	0.055	15%	0.152	C	C	.	.	H	α-helix	trans	-120.2	-7.3	-171.4	-58.8	-68.1	0	0	0	114.1	Q431 Q438 C463 D464 A465 C472 V474	Q431-Y435 PolarHBondContact O-N 2.97Å; Y435-Q438 WeakPolarHBondContact O-CB 3.33Å; Y435-Q438 VanDerWaalsContact O-CG 3.23Å; Y435-Q438 WeakPolarHBondContact O-CG 3.48Å; Y435-Q438 PolarHBondContact O-N 2.98Å; Y435-Q438 PolarHBondContact O-NE2 3.17Å; Y435-C463 HydrophobicContact CD1-CB 3.93Å; Y435-C463 HydrophobicContact CD2-CB 4.2Å; Y435-C463 WeakPolarHBondContact CD2-O 3.35Å; Y435-C463 HydrophobicContact CG-CB 3.7Å; Y435-D464 PolarHBondContact OH-O 2.9Å; Y435-A465 WeakPolarHBondContact OH-CA 3.01Å; Y435-C472 HydrophobicContact CD1-CB 4.22Å; Y435-C472 HydrophobicContact CE1-CB 4.2Å; Y435-V474 HydrophobicContact CD1-CG1 4.07Å; Y435-V474 HydrophobicContact CE1-CG1 3.48Å; Y435-V474 VanDerWaalsContact CE1-CG1 3.48Å
436	G	85.7	Confident	81.2	Confident	11 Å²	11	32.3 Å²	32.3	11%	0.113	17%	0.172	C	C	.	.	T	Hydrogen-bonded Turn	trans	64	-138.6	-174.4	0	0	0	0	0	112.4	S69 Y432	S69-G436 WeakPolarHBondContact OG-CA 3.39Å; Y432-G436 WeakPolarHBondContact O-CA 2.99Å; Y432-G436 PolarHBondContact O-N 3.37Å
437	S	84.4	Confident	79.2	Confident	49 Å²	49	38 Å²	38	34%	0.343	21%	0.209	S	C	.	.	T	Hydrogen-bonded Turn	trans	-96.9	23.9	174.4	68.6	0	0	0	0	113.6	S69 Q357	S69-S437 PolarHBondContact OG-N 3.46Å; Q357-S437 VanDerWaalsContact CD-OG 3.22Å; Q357-S437 PolarHBondContact NE2-OG 3.11Å; Q357-S437 VanDerWaalsContact NE2-OG 3.09Å; Q357-S437 PolarHBondContact OE1-OG 3.47Å
438	Q	86.8	Confident	77.2	Confident	5 Å²	5	42.1 Å²	42.1	2%	0.023	24%	0.238	C	C	.	.			trans	-67.9	144.2	-178.3	-70	177.6	81.7	0	0	112.2	K72 Y435 C463 T473	K72-Q438 HydrophobicContact CD-CB 4.24Å; K72-Q438 HydrophobicContact CD-CG 4.05Å; Y435-Q438 WeakPolarHBondContact O-CB 3.33Å; Y435-Q438 VanDerWaalsContact O-CG 3.23Å; Y435-Q438 WeakPolarHBondContact O-CG 3.48Å; Y435-Q438 PolarHBondContact O-N 2.98Å; Y435-Q438 PolarHBondContact O-NE2 3.17Å; Q438-C463 HydrophobicContact CB-CB 4.21Å; Q438-C463 WeakPolarHBondContact CB-SG 3.37Å; Q438-C463 PolarHBondContact O-N 3.49Å; Q438-T473 PolarHBondContact NE2-O 3.42Å; Q438-T473 PolarHBondContact OE1-OG1 3Å
439	N	87.3	Confident	75.4	Confident	29 Å²	29	50 Å²	50	16%	0.155	28%	0.28	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-119.2	152.6	169.1	-62.4	-35	0	0	0	109.4	Q74 G76 P460 R461 R462	Q74-N439 PolarHBondContact O-ND2 3.19Å; G76-N439 WeakPolarHBondContact CA-O 3.47Å; N439-P460 HydrophobicContact CB-CB 4.21Å; N439-R461 CarbonylContact C-O 3.42Å; N439-R461 WeakPolarHBondContact CA-O 3.44Å; N439-R461 WeakPolarHBondContact CB-O 3.48Å; N439-R462 VanDerWaalsContact OD1-CA 3.32Å; N439-R462 WeakPolarHBondContact OD1-CA 3.37Å; N439-R462 VanDerWaalsContact OD1-CG 3.31Å; N439-R462 WeakPolarHBondContact OD1-CG 3.36Å
440	Y	86.9	Confident	73.7	Confident	8 Å²	8	55.4 Å²	55.4	3%	0.031	31%	0.312	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-120.8	164.1	169.1	70.4	-82.5	0	0	0	110.1	I442 P460 R461 R462 D464 A467	Y440-I442 HydrophobicContact CD2-CD1 4.45Å; Y440-I442 HydrophobicContact CD2-CG1 3.83Å; Y440-I442 HydrophobicContact CE2-CD1 3.52Å; Y440-I442 HydrophobicContact CE2-CG1 3.32Å; Y440-P460 WeakPolarHBondContact O-CA 3.25Å; Y440-R461 WeakPolarHBondContact CD1-O 3.49Å; Y440-R461 HydrophobicContact CE1-CB 4.19Å; Y440-R461 HydrophobicContact CE1-CG 4.19Å; Y440-R461 PolarHBondContact N-O 3.08Å; Y440-R461 PolarHBondContact O-N 2.95Å; Y440-R462 WeakPolarHBondContact CE1-O 3.34Å; Y440-D464 WeakPolarHBondContact CE1-OD1 3.21Å; Y440-D464 PolarHBondContact OH-OD1 3.46Å; Y440-A467 HydrophobicContact CD1-CB 3.63Å; Y440-A467 HydrophobicContact CD2-CB 4.23Å; Y440-A467 HydrophobicContact CE1-CB 3.53Å; Y440-A467 HydrophobicContact CE2-CB 4.14Å; Y440-A467 HydrophobicContact CG-CB 3.96Å
441	L	86.1	Confident	71.9	Confident	50 Å²	50	63 Å²	63	26%	0.262	35%	0.347	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-99	125.5	-175.9	-72.9	176.3	0	0	0	109.9	N75 T77 P458 P460 Q471	N75-L441 WeakPolarHBondContact O-CD2 3.48Å; T77-L441 HydrophobicContact CG2-CD1 3.84Å; L441-P458 HydrophobicContact CB-CB 4.35Å; L441-P458 HydrophobicContact CD1-CB 4.3Å; L441-P458 HydrophobicContact CD2-CB 3.97Å; L441-P458 HydrophobicContact CG-CB 4.44Å; L441-P460 HydrophobicContact CD2-CB 4.45Å; L441-Q471 VanDerWaalsContact N-OE1 3.14Å; L441-Q471 PolarHBondContact O-OE1 3.25Å
442	I	83.3	Confident	70.3	Confident	58 Å²	58	72.8 Å²	72.8	30%	0.297	39%	0.389	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-107.2	134.5	169.5	-63.4	-178	0	0	0	108.9	Y440 S444 P458 V459 R461	Y440-I442 HydrophobicContact CD2-CD1 4.45Å; Y440-I442 HydrophobicContact CD2-CG1 3.83Å; Y440-I442 HydrophobicContact CE2-CD1 3.52Å; Y440-I442 HydrophobicContact CE2-CG1 3.32Å; I442-S444 PolarHBondContact O-N 3.2Å; I442-P458 WeakPolarHBondContact O-CA 3.32Å; I442-V459 PolarHBondContact N-O 3.35Å; I442-V459 PolarHBondContact O-N 3.09Å; I442-R461 HydrophobicContact CD1-CB 3.96Å; I442-R461 HydrophobicContact CD1-CG 4.29Å; I442-R461 HydrophobicContact CG1-CB 4.37Å
443	E	75.8	Confident	68.6	Low	135 Å²	135	75 Å²	75	63%	0.631	41%	0.412	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-74.9	109	171.2	-159.7	168.7	-163.6	0	0	109.2	T456	E443-T456 VanDerWaalsContact CG-CB 3.49Å; E443-T456 HydrophobicContact CG-CG2 3.84Å; E443-T456 WeakPolarHBondContact OE1-CB 3.1Å; E443-T456 VanDerWaalsContact OE1-CG2 3.31Å; E443-T456 WeakPolarHBondContact OE1-CG2 3.14Å; E443-T456 PolarHBondContact OE1-OG1 3.02Å
444	S	63.5	Low	66.7	Low	28 Å²	28	82.7 Å²	82.7	20%	0.196	45%	0.454	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-99.1	121.8	179.1	70.1	0	0	0	0	110.6	I442 I446 L457 V459	I442-S444 PolarHBondContact O-N 3.2Å; S444-I446 VanDerWaalsContact C-N 3.28Å; S444-I446 PolarHBondContact O-N 2.79Å; S444-L457 PolarHBondContact N-O 2.97Å; S444-L457 PolarHBondContact OG-O 3.49Å; S444-V459 VanDerWaalsContact OG-CG2 3.3Å; S444-V459 WeakPolarHBondContact OG-CG2 3.32Å
445	N	55.8	Low	65.1	Low	136 Å²	136	86.4 Å²	86.4	73%	0.727	48%	0.48	S	S	*	.			trans	-77.8	81.1	170.3	-80	-13.2	0	0	0	109	T447 T456	N445-T447 PolarHBondContact O-N 2.8Å; N445-T456 WeakPolarHBondContact OD1-CG2 3.19Å
446	I	53.4	Low	63.9	Low	90 Å²	90	88.4 Å²	88.4	46%	0.462	49%	0.494	S	S	.	.			trans	-81.9	103.9	168.6	-54.7	175.7	0	0	0	107	S444 S448	S444-I446 VanDerWaalsContact C-N 3.28Å; S444-I446 PolarHBondContact O-N 2.79Å; I446-S448 PolarHBondContact O-N 3.1Å
447	T	46.2	Very low	63.1	Low	134 Å²	134	92.8 Å²	92.8	82%	0.822	51%	0.514	S	S	*	.			trans	-66.9	88.6	162.9	41.2	0	0	0	0	108.2	N445 D449	N445-T447 PolarHBondContact O-N 2.8Å; T447-D449 PolarHBondContact O-N 3.08Å
448	S	45.4	Very low	62.7	Low	86 Å²	86	94 Å²	94	60%	0.601	52%	0.521	S	S	*	.			trans	-75.6	117.9	169.1	-69.9	0	0	0	0	108.7	I446 V450	I446-S448 PolarHBondContact O-N 3.1Å; S448-V450 PolarHBondContact O-N 3.25Å
449	D	48.7	Very low	62.5	Low	169 Å²	169	97 Å²	97	90%	0.904	54%	0.539	S	S	*	.	S	Bend	trans	-76.6	18.7	-170.8	-135.8	0.9	0	0	0	114.7	T447	T447-D449 PolarHBondContact O-N 3.08Å
450	V	50.6	Low	62.3	Low	114 Å²	114	98.6 Å²	98.6	69%	0.691	55%	0.551	S	S	*	*	S	Bend	trans	-143.1	109.2	175.3	-174.2	0	0	0	0	109.2	S448	S448-V450 PolarHBondContact O-N 3.25Å
451	H	46.6	Very low	62.1	Low	171 Å²	171	103.7 Å²	103.7	79%	0.792	57%	0.57	S	S	*	*	S	Bend	trans	91.8	113	179.4	-56.2	-30.1	0	0	0	116.2	G453	H451-G453 PolarHBondContact O-N 3.32Å
452	K	47	Very low	61.9	Low	228 Å²	228	109.3 Å²	109.3	99%	0.991	59%	0.588	S	S	*	*	S	Bend	trans	-52	96.2	172.6	-80.7	176.4	171.8	176.2	0	111.3
453	G	50.3	Low	61.9	Low	49 Å²	49	106.9 Å²	106.9	51%	0.505	58%	0.576	S	S	.	*			trans	-167.5	121.5	162.7	0	0	0	0	0	107.9	H451 S455	H451-G453 PolarHBondContact O-N 3.32Å; G453-S455 PolarHBondContact O-N 3.23Å
454	N	47.7	Very low	62.1	Low	166 Å²	166	101.2 Å²	101.2	89%	0.888	55%	0.55	S	S	*	*			trans	-70.5	81.4	168	-80.8	1	0	0	0	107.6	T456	N454-T456 PolarHBondContact O-N 3.32Å
455	S	52.3	Low	62.5	Low	84 Å²	84	100.5 Å²	100.5	59%	0.587	55%	0.546	S	S	*	.			trans	-85.8	97.5	174.8	-55.8	0	0	0	0	107.8	G453 L457	G453-S455 PolarHBondContact O-N 3.23Å; S455-L457 PolarHBondContact O-N 2.86Å
456	T	59.1	Low	63.2	Low	56 Å²	56	97.4 Å²	97.4	34%	0.344	53%	0.529	S	S	.	.			trans	-74.1	105.4	172.2	49.8	0	0	0	0	108.9	E443 N445 N454	E443-T456 VanDerWaalsContact CG-CB 3.49Å; E443-T456 HydrophobicContact CG-CG2 3.84Å; E443-T456 WeakPolarHBondContact OE1-CB 3.1Å; E443-T456 VanDerWaalsContact OE1-CG2 3.31Å; E443-T456 WeakPolarHBondContact OE1-CG2 3.14Å; E443-T456 PolarHBondContact OE1-OG1 3.02Å; N445-T456 WeakPolarHBondContact OD1-CG2 3.19Å; N454-T456 PolarHBondContact O-N 3.32Å
457	L	68.8	Low	64.2	Low	103 Å²	103	93.9 Å²	93.9	54%	0.539	51%	0.514	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-90.5	122.6	176.7	-84.9	160.3	0	0	0	108.9	S444 S455 V459	S444-L457 PolarHBondContact N-O 2.97Å; S444-L457 PolarHBondContact OG-O 3.49Å; S455-L457 PolarHBondContact O-N 2.86Å; L457-V459 PolarHBondContact O-N 2.92Å
458	P	75.1	Confident	65.7	Low	75 Å²	75	90.2 Å²	90.2	49%	0.487	49%	0.492	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-72	120.3	176.7	29.7	-33.2	0	0	0	109	L441 I442	L441-P458 HydrophobicContact CB-CB 4.35Å; L441-P458 HydrophobicContact CD1-CB 4.3Å; L441-P458 HydrophobicContact CD2-CB 3.97Å; L441-P458 HydrophobicContact CG-CB 4.44Å; I442-P458 WeakPolarHBondContact O-CA 3.32Å
459	V	82.2	Confident	66.8	Low	68 Å²	68	91.1 Å²	91.1	41%	0.412	49%	0.487	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-103.3	128.4	178.6	177	0	0	0	0	108.8	I442 S444 L457 R461	I442-V459 PolarHBondContact N-O 3.35Å; I442-V459 PolarHBondContact O-N 3.09Å; S444-V459 VanDerWaalsContact OG-CG2 3.3Å; S444-V459 WeakPolarHBondContact OG-CG2 3.32Å; L457-V459 PolarHBondContact O-N 2.92Å; V459-R461 PolarHBondContact O-N 3.32Å
460	P	82.9	Confident	68	Low	62 Å²	62	89.8 Å²	89.8	40%	0.403	48%	0.48	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-71.1	125.9	175.9	28.4	-32.8	0	0	0	110.4	N439 Y440 L441	N439-P460 HydrophobicContact CB-CB 4.21Å; Y440-P460 WeakPolarHBondContact O-CA 3.25Å; L441-P460 HydrophobicContact CD2-CB 4.45Å
461	R	83.1	Confident	69.4	Low	116 Å²	116	87.4 Å²	87.4	44%	0.438	46%	0.461	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-117.1	146.3	170.2	-175.1	178	170.1	171.9	-7.7	109.2	N439 Y440 I442 V459 D464	N439-R461 CarbonylContact C-O 3.42Å; N439-R461 WeakPolarHBondContact CA-O 3.44Å; N439-R461 WeakPolarHBondContact CB-O 3.48Å; Y440-R461 WeakPolarHBondContact CD1-O 3.49Å; Y440-R461 HydrophobicContact CE1-CB 4.19Å; Y440-R461 HydrophobicContact CE1-CG 4.19Å; Y440-R461 PolarHBondContact N-O 3.08Å; Y440-R461 PolarHBondContact O-N 2.95Å; I442-R461 HydrophobicContact CD1-CB 3.96Å; I442-R461 HydrophobicContact CD1-CG 4.29Å; I442-R461 HydrophobicContact CG1-CB 4.37Å; V459-R461 PolarHBondContact O-N 3.32Å; R461-D464 IonicContact CZ-OD2 3.19Å; R461-D464 VanDerWaalsContact CZ-OD2 3.28Å; R461-D464 IonicContact NE-OD2 2.62Å; R461-D464 PolarHBondContact NE-OD2 3.46Å; R461-D464 IonicContact NH2-OD2 3.63Å; R461-D464 PolarHBondContact NH2-OD2 2.82Å
462	R	82.8	Confident	71.2	Confident	167 Å²	167	80 Å²	80	63%	0.63	43%	0.428	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-63.1	138.1	175.2	-73.5	-178.4	-176.4	170.1	1.7	110.6	N439 Y440 D464	N439-R462 VanDerWaalsContact OD1-CA 3.32Å; N439-R462 WeakPolarHBondContact OD1-CA 3.37Å; N439-R462 VanDerWaalsContact OD1-CG 3.31Å; N439-R462 WeakPolarHBondContact OD1-CG 3.36Å; Y440-R462 WeakPolarHBondContact CE1-O 3.34Å; R462-D464 PolarHBondContact O-N 3.23Å
463	C	83.4	Confident	72.9	Confident	7 Å²	7	70.4 Å²	70.4	5%	0.047	39%	0.389	C	S	.	.			trans	-53.8	123.1	172.9	-72.7	0	0	0	0	110.5	Q431 Y435 Q438 C472	Q431-C463 PolarHBondContact OE1-O 2.92Å; Y435-C463 HydrophobicContact CD1-CB 3.93Å; Y435-C463 HydrophobicContact CD2-CB 4.2Å; Y435-C463 WeakPolarHBondContact CD2-O 3.35Å; Y435-C463 HydrophobicContact CG-CB 3.7Å; Q438-C463 HydrophobicContact CB-CB 4.21Å; Q438-C463 WeakPolarHBondContact CB-SG 3.37Å; Q438-C463 PolarHBondContact O-N 3.49Å; C463-C472 VanDerWaalsContact CA-SG 3.6Å; C463-C472 HydrophobicContact CB-CB 3.82Å; C463-C472 WeakPolarHBondContact CB-SG 3.39Å; C463-C472 WeakPolarHBondContact SG-CB 3.35Å; C463-C472 CovalentContact SG-SG 2.03Å; C463-C472 PolarHBondContact SG-SG 3.05Å
464	D	78.9	Confident	74.6	Confident	16 Å²	16	69.5 Å²	69.5	9%	0.086	37%	0.373	C	S	.	.			trans	-129.3	176.1	170.9	50.1	15.2	0	0	0	107.7	Y435 Y440 R461 R462 D466 A467	Y435-D464 PolarHBondContact OH-O 2.9Å; Y440-D464 WeakPolarHBondContact CE1-OD1 3.21Å; Y440-D464 PolarHBondContact OH-OD1 3.46Å; R461-D464 IonicContact CZ-OD2 3.19Å; R461-D464 VanDerWaalsContact CZ-OD2 3.28Å; R461-D464 IonicContact NE-OD2 2.62Å; R461-D464 PolarHBondContact NE-OD2 3.46Å; R461-D464 IonicContact NH2-OD2 3.63Å; R461-D464 PolarHBondContact NH2-OD2 2.82Å; R462-D464 PolarHBondContact O-N 3.23Å; D464-D466 PolarHBondContact O-N 2.03Å; D464-D466 VanDerWaalsContact O-N 3.14Å; D464-D466 PolarHBondContact OD1-N 2.99Å; D464-A467 VanDerWaalsContact O-CB 3.24Å; D464-A467 WeakPolarHBondContact O-CB 3.27Å; D464-A467 PolarHBondContact O-N 3.21Å; D464-A467 VanDerWaalsContact O-N 3.08Å; D464-A467 PolarHBondContact OD1-N 2.78Å
465	A	71.6	Confident	76.5	Confident	13 Å²	13	61.6 Å²	61.6	11%	0.107	33%	0.331	C	S	.	.	T	Hydrogen-bonded Turn	trans	-72.5	-2.1	177.6	0	0	0	0	0	113.1	F341 Y435 A467	F341-A465 VanDerWaalsContact CA-CB 3.47Å; F341-A465 HydrophobicContact CB-CB 3.87Å; F341-A465 HydrophobicContact CD1-CB 3.75Å; F341-A465 HydrophobicContact CG-CB 4.3Å; F341-A465 WeakPolarHBondContact O-CA 3.35Å; F341-A465 WeakPolarHBondContact O-CB 3.45Å; F341-A465 PolarHBondContact O-N 2.78Å; Y435-A465 WeakPolarHBondContact OH-CA 3.01Å; A465-A467 VanDerWaalsContact C-N 3.34Å
466	D	72	Confident	78.1	Confident	71 Å²	71	59.8 Å²	59.8	38%	0.38	31%	0.312	S	S	.	.	T	Hydrogen-bonded Turn	trans	-82.7	-13.7	169.7	-74.1	-34.6	0	0	0	113.4	K173 D464	K173-D466 IonicContact NZ-OD1 2.74Å; K173-D466 PolarHBondContact NZ-OD1 3.37Å; D464-D466 PolarHBondContact O-N 2.03Å; D464-D466 VanDerWaalsContact O-N 3.14Å; D464-D466 PolarHBondContact OD1-N 2.99Å
467	A	74.5	Confident	79.3	Confident	16 Å²	16	57.3 Å²	57.3	13%	0.132	30%	0.296	C	S	.	.	S	Bend	trans	-63.8	144.5	179.5	0	0	0	0	0	112.4	Y440 D464 A465 C472	Y440-A467 HydrophobicContact CD1-CB 3.63Å; Y440-A467 HydrophobicContact CD2-CB 4.23Å; Y440-A467 HydrophobicContact CE1-CB 3.53Å; Y440-A467 HydrophobicContact CE2-CB 4.14Å; Y440-A467 HydrophobicContact CG-CB 3.96Å; D464-A467 VanDerWaalsContact O-CB 3.24Å; D464-A467 WeakPolarHBondContact O-CB 3.27Å; D464-A467 PolarHBondContact O-N 3.21Å; D464-A467 VanDerWaalsContact O-N 3.08Å; D464-A467 PolarHBondContact OD1-N 2.78Å; A465-A467 VanDerWaalsContact C-N 3.34Å; A467-C472 HydrophobicContact CB-CB 4.01Å; A467-C472 WeakPolarHBondContact CB-SG 3.23Å
468	P	77.2	Confident	79.9	Confident	57 Å²	57	53.1 Å²	53.1	37%	0.37	27%	0.273	S	S	.	.			trans	-66.5	143.9	172.9	25.1	-29.5	0	0	0	111.2	D470 Q471 C472	P468-D470 VanDerWaalsContact C-N 3.27Å; P468-D470 PolarHBondContact O-N 3.46Å; P468-Q471 HydrophobicContact CG-CB 3.99Å; P468-Q471 HydrophobicContact CG-CG 3.81Å; P468-Q471 PolarHBondContact O-N 3.03Å; P468-C472 PolarHBondContact O-N 3.11Å
469	E	67.3	Low	79.9	Confident	105 Å²	105	50 Å²	50	49%	0.491	25%	0.253	S	S	.	.	G	3₁₀ helix	trans	-54.9	-40.7	-171.8	-67	164	-169.7	0	0	112.6	F176 Q471	F176-E469 HydrophobicContact CD1-CG 3.99Å; F176-E469 WeakPolarHBondContact CD1-OE1 3.1Å; F176-E469 HydrophobicContact CE1-CB 4.31Å; F176-E469 HydrophobicContact CE1-CG 3.56Å; F176-E469 VanDerWaalsContact CE1-OE1 3.29Å; F176-E469 WeakPolarHBondContact CE1-OE1 3.31Å; F176-E469 VanDerWaalsContact CE1-OE2 3.26Å; F176-E469 WeakPolarHBondContact CE1-OE2 3.46Å; F176-E469 WeakPolarHBondContact CE2-OE2 3.21Å; F176-E469 VanDerWaalsContact CG-OE1 3.3Å; F176-E469 WeakPolarHBondContact CG-OE1 3.31Å; F176-E469 HydrophobicContact CZ-CG 4.16Å; F176-E469 WeakPolarHBondContact CZ-OE2 3.45Å; E469-Q471 PolarHBondContact O-N 3.04Å
470	D	74.8	Confident	79.7	Confident	141 Å²	141	46.9 Å²	46.9	75%	0.754	23%	0.233	S	C	*	.	G	3₁₀ helix	trans	-71.4	-12.5	-177.7	-45.1	-31.9	0	0	0	113.3	P468	P468-D470 VanDerWaalsContact C-N 3.27Å; P468-D470 PolarHBondContact O-N 3.46Å
471	Q	79.6	Confident	79.5	Confident	65 Å²	65	44 Å²	44	30%	0.304	22%	0.215	S	C	.	.	G	3₁₀ helix	trans	-112.2	-9.7	-172.2	-58.2	-168.7	17.5	0	0	114.5	K72 L441 P468 E469	K72-Q471 WeakPolarHBondContact CE-O 3.41Å; K72-Q471 PolarHBondContact NZ-O 3.49Å; L441-Q471 VanDerWaalsContact N-OE1 3.14Å; L441-Q471 PolarHBondContact O-OE1 3.25Å; P468-Q471 HydrophobicContact CG-CB 3.99Å; P468-Q471 HydrophobicContact CG-CG 3.81Å; P468-Q471 PolarHBondContact O-N 3.03Å; E469-Q471 PolarHBondContact O-N 3.04Å
472	C	84.6	Confident	79.3	Confident	14 Å²	14	38.9 Å²	38.9	10%	0.095	20%	0.196	C	C	.	.			trans	-137.6	120.6	176.2	-68.8	0	0	0	0	110.5	Y435 C463 A467 P468	Y435-C472 HydrophobicContact CD1-CB 4.22Å; Y435-C472 HydrophobicContact CE1-CB 4.2Å; C463-C472 VanDerWaalsContact CA-SG 3.6Å; C463-C472 HydrophobicContact CB-CB 3.82Å; C463-C472 WeakPolarHBondContact CB-SG 3.39Å; C463-C472 WeakPolarHBondContact SG-CB 3.35Å; C463-C472 CovalentContact SG-SG 2.03Å; C463-C472 PolarHBondContact SG-SG 3.05Å; A467-C472 HydrophobicContact CB-CB 4.01Å; A467-C472 WeakPolarHBondContact CB-SG 3.23Å; P468-C472 PolarHBondContact O-N 3.11Å
473	T	83.6	Confident	79.1	Confident	28 Å²	28	31 Å²	31	17%	0.172	17%	0.166	C	C	.	.	P	Polyproline II helix	trans	-93.5	135.5	176.5	53.4	0	0	0	0	110	V68 Q438	V68-T473 WeakPolarHBondContact CG1-O 3.33Å; V68-T473 WeakPolarHBondContact CG1-OG1 3.24Å; Q438-T473 PolarHBondContact NE2-O 3.42Å; Q438-T473 PolarHBondContact OE1-OG1 3Å
474	V	85.1	Confident	79.1	Confident	29 Å²	29	30.8 Å²	30.8	18%	0.176	16%	0.164	C	C	.	.	P	Polyproline II helix	trans	-89.9	150.2	176.3	-66.4	0	0	0	0	111	M434 Y435 Y478	M434-V474 HydrophobicContact CE-CG1 3.79Å; M434-V474 HydrophobicContact CG-CG1 4.12Å; M434-V474 WeakPolarHBondContact O-CA 3.43Å; Y435-V474 HydrophobicContact CD1-CG1 4.07Å; Y435-V474 HydrophobicContact CE1-CG1 3.48Å; Y435-V474 VanDerWaalsContact CE1-CG1 3.48Å; V474-Y478 HydrophobicContact CB-CD1 4.49Å
475	T	87.4	Confident	79.2	Confident	0 Å²	0	33.3 Å²	33.3	0%	0	17%	0.173	C	C	.	.	P	Polyproline II helix	trans	-63	144.2	173.9	52.6	0	0	0	0	112.3	D64 I65 V68 V433 M434 T477 Y478	D64-T475 WeakPolarHBondContact OD2-CB 3.48Å; I65-T475 HydrophobicContact CG1-CG2 4.05Å; V68-T475 HydrophobicContact CB-CG2 4.43Å; V68-T475 HydrophobicContact CG2-CG2 4.2Å; V433-T475 WeakPolarHBondContact O-CG2 3.29Å; V433-T475 PolarHBondContact O-OG1 2.86Å; M434-T475 PolarHBondContact O-N 3.31Å; T475-T477 VanDerWaalsContact C-N 3.27Å; T475-T477 PolarHBondContact O-N 3.42Å; T475-Y478 WeakPolarHBondContact O-CB 3.38Å; T475-Y478 PolarHBondContact O-N 3.25Å
476	R	86.4	Confident	79.9	Confident	47 Å²	47	36.1 Å²	36.1	18%	0.177	18%	0.182	C	C	.	.	H	α-helix	trans	-69.7	-27.6	-178.7	-62.1	-55.7	-178.3	173.7	-2	112	D64 E91 V94 Y98 L479 F480	D64-R476 PolarHBondContact OD1-N 2.84Å; D64-R476 PolarHBondContact OD2-N 3.34Å; E91-R476 IonicContact OE2-CZ 3.83Å; E91-R476 IonicContact OE2-NH2 3.69Å; E91-R476 PolarHBondContact OE2-NH2 3.09Å; V94-R476 HydrophobicContact CG1-CB 4.3Å; V94-R476 HydrophobicContact CG1-CG 4.42Å; Y98-R476 HydrophobicContact CD2-CB 4.33Å; R476-L479 WeakPolarHBondContact O-CB 3.32Å; R476-L479 PolarHBondContact O-N 3.01Å; R476-F480 VanDerWaalsContact O-CD2 3.31Å; R476-F480 WeakPolarHBondContact O-CD2 3.32Å; R476-F480 PolarHBondContact O-N 2.96Å
477	T	83.7	Confident	80.7	Confident	3 Å²	3	33.3 Å²	33.3	2%	0.018	17%	0.167	C	C	.	.	H	α-helix	trans	-61.9	-43	174.3	-51.2	0	0	0	0	112.8	L61 D64 Y98 T475 L479 F480 L481	L61-T477 HydrophobicContact CD1-CG2 3.9Å; D64-T477 PolarHBondContact OD2-N 2.69Å; D64-T477 PolarHBondContact OD2-OG1 3.41Å; Y98-T477 WeakPolarHBondContact CE2-OG1 3.42Å; Y98-T477 PolarHBondContact OH-OG1 3.43Å; T475-T477 VanDerWaalsContact C-N 3.27Å; T475-T477 PolarHBondContact O-N 3.42Å; T477-L479 PolarHBondContact O-N 3.33Å; T477-F480 PolarHBondContact O-N 2.64Å; T477-F480 VanDerWaalsContact O-N 3.17Å; T477-L481 HydrophobicContact CG2-CD1 3.8Å; T477-L481 HydrophobicContact CG2-CG 4.4Å; T477-L481 PolarHBondContact O-N 3.19Å
478	Y	81.1	Confident	81.3	Confident	15 Å²	15	32.7 Å²	32.7	6%	0.059	16%	0.161	C	C	.	.	H	α-helix	trans	-56.8	-41.7	177.6	172.4	-104.2	0	0	0	110.6	Y426 M434 V474 T475 F480 L481 H482	Y426-Y478 AromaticContact CD2-CD2 3.94Å; Y426-Y478 HydrophobicContact CD2-CD2 3.94Å; Y426-Y478 HydrophobicContact CE1-CE2 4.26Å; Y426-Y478 AromaticContact CE2-CD2 3.31Å; Y426-Y478 HydrophobicContact CE2-CD2 3.31Å; Y426-Y478 AromaticContact CE2-CE2 3.59Å; Y426-Y478 HydrophobicContact CE2-CE2 3.59Å; Y426-Y478 HydrophobicContact CE2-CG 4.37Å; Y426-Y478 AromaticContact CZ-CD2 3.67Å; Y426-Y478 AromaticContact CZ-CE2 3.43Å; Y426-Y478 VanDerWaalsContact CZ-CE2 3.43Å; Y426-Y478 WeakPolarHBondContact OH-CE2 3.4Å; M434-Y478 HydrophobicContact CE-CD1 4.4Å; M434-Y478 HydrophobicContact CE-CE1 3.84Å; M434-Y478 HydrophobicContact CG-CD1 4.45Å; M434-Y478 HydrophobicContact CG-CG 4.38Å; M434-Y478 HydrophobicContact SD-CE1 4.4Å; M434-Y478 HydrophobicContact SD-CE2 4.3Å; V474-Y478 HydrophobicContact CB-CD1 4.49Å; T475-Y478 WeakPolarHBondContact O-CB 3.38Å; T475-Y478 PolarHBondContact O-N 3.25Å; Y478-F480 VanDerWaalsContact C-N 3.31Å; Y478-F480 PolarHBondContact O-N 3.19Å; Y478-L481 PolarHBondContact O-N 3.36Å; Y478-H482 HydrophobicContact CD2-CB 4.09Å; Y478-H482 AromaticContact CD2-CD2 3.41Å; Y478-H482 VanDerWaalsContact CD2-CD2 3.41Å; Y478-H482 WeakPolarHBondContact CD2-CD2 3.12Å; Y478-H482 AromaticContact CD2-CG 3.86Å; Y478-H482 HydrophobicContact CE2-CB 3.69Å; Y478-H482 AromaticContact CE2-CD2 3.55Å; Y478-H482 AromaticContact CE2-CG 3.55Å; Y478-H482 WeakPolarHBondContact O-CB 3.33Å; Y478-H482 PolarHBondContact O-N 3.44Å
479	L	76.4	Confident	81.8	Confident	11 Å²	11	30.4 Å²	30.4	6%	0.058	15%	0.147	C	C	.	.	H	α-helix	trans	-57.8	-38.7	179	-149.7	112.6	0	0	0	113.4	L181 L187 R476 T477 K483	L181-L479 HydrophobicContact CD1-CD1 3.32Å; L181-L479 HydrophobicContact CD1-CD2 4.4Å; L181-L479 HydrophobicContact CD1-CG 3.54Å; L181-L479 HydrophobicContact CD2-CG 4.06Å; L181-L479 WeakPolarHBondContact CD2-O 3.19Å; L181-L479 HydrophobicContact CG-CD1 3.85Å; L181-L479 HydrophobicContact CG-CD2 3.97Å; L181-L479 HydrophobicContact CG-CG 3.52Å; L187-L479 HydrophobicContact CD2-CD2 3.93Å; R476-L479 WeakPolarHBondContact O-CB 3.32Å; R476-L479 PolarHBondContact O-N 3.01Å; T477-L479 PolarHBondContact O-N 3.33Å; L479-K483 WeakPolarHBondContact O-CB 3.39Å
480	F	78	Confident	83	Confident	1 Å²	1	27 Å²	27	0%	0.004	14%	0.137	C	C	.	.	H	α-helix	trans	-76.4	-40.3	178.4	-79	-78.2	0	0	0	113.4	L95 Y98 Y102 L187 L190 S191 R476 T477 Y478	L95-F480 HydrophobicContact CD1-CE2 3.59Å; L95-F480 HydrophobicContact CD1-CZ 3.7Å; Y98-F480 HydrophobicContact CG-CD2 4.41Å; Y98-F480 HydrophobicContact CG-CE2 4.21Å; Y102-F480 HydrophobicContact CD2-CD1 4.35Å; Y102-F480 HydrophobicContact CD2-CG 4.37Å; Y102-F480 HydrophobicContact CE2-CB 4.13Å; Y102-F480 HydrophobicContact CE2-CD1 4.48Å; Y102-F480 HydrophobicContact CE2-CD2 4.27Å; Y102-F480 HydrophobicContact CE2-CG 4.06Å; L187-F480 HydrophobicContact CD1-CD1 4.43Å; L187-F480 HydrophobicContact CD1-CE1 3.5Å; L187-F480 HydrophobicContact CD1-CE2 4.39Å; L187-F480 HydrophobicContact CD1-CZ 3.49Å; L187-F480 VanDerWaalsContact CD1-CZ 3.49Å; L187-F480 HydrophobicContact CG-CE1 4.08Å; L190-F480 HydrophobicContact CD2-CD1 3.89Å; L190-F480 HydrophobicContact CD2-CE1 3.62Å; S191-F480 WeakPolarHBondContact CB-O 3.44Å; R476-F480 VanDerWaalsContact O-CD2 3.31Å; R476-F480 WeakPolarHBondContact O-CD2 3.32Å; R476-F480 PolarHBondContact O-N 2.96Å; T477-F480 PolarHBondContact O-N 2.64Å; T477-F480 VanDerWaalsContact O-N 3.17Å; Y478-F480 VanDerWaalsContact C-N 3.31Å; Y478-F480 PolarHBondContact O-N 3.19Å
481	L	79	Confident	83.8	Confident	3 Å²	3	20.3 Å²	20.3	2%	0.016	10%	0.102	C	C	.	.	H	α-helix	trans	-85.6	-26.9	-169.8	-65.4	176.1	0	0	0	113.4	I194 T198 Y423 T477 Y478	I194-L481 HydrophobicContact CG2-CD2 4.35Å; T198-L481 HydrophobicContact CG2-CD2 4.11Å; Y423-L481 HydrophobicContact CD2-CB 4.49Å; T477-L481 HydrophobicContact CG2-CD1 3.8Å; T477-L481 HydrophobicContact CG2-CG 4.4Å; T477-L481 PolarHBondContact O-N 3.19Å; Y478-L481 PolarHBondContact O-N 3.36Å
482	H	77.9	Confident	84.3	Confident	7 Å²	7	17.9 Å²	17.9	3%	0.032	9%	0.09	C	C	.	.	S	Bend	trans	-108.9	7.4	-176	-71.4	-86.2	0	0	0	114	F178 Y423 Y426 Y478 F484 S488	F178-H482 WeakPolarHBondContact CE1-O 3.15Å; Y423-H482 AromaticContact CD2-NE2 3.76Å; Y423-H482 AromaticContact CE2-CE1 3.29Å; Y423-H482 WeakPolarHBondContact CE2-CE1 3.44Å; Y423-H482 AromaticContact CE2-NE2 3.42Å; Y423-H482 WeakPolarHBondContact CE2-NE2 3.43Å; Y426-H482 AromaticContact CD1-CE1 3.59Å; Y426-H482 AromaticContact CD1-NE2 3.16Å; Y426-H482 WeakPolarHBondContact CD1-NE2 3.48Å; Y426-H482 AromaticContact CE1-CE1 3.48Å; Y426-H482 VanDerWaalsContact CE1-CE1 3.48Å; Y426-H482 WeakPolarHBondContact CE1-CE1 3.3Å; Y426-H482 AromaticContact CE1-NE2 3.38Å; Y426-H482 WeakPolarHBondContact CE1-NE2 3.43Å; Y426-H482 AromaticContact CG-NE2 3.67Å; Y478-H482 HydrophobicContact CD2-CB 4.09Å; Y478-H482 AromaticContact CD2-CD2 3.41Å; Y478-H482 VanDerWaalsContact CD2-CD2 3.41Å; Y478-H482 WeakPolarHBondContact CD2-CD2 3.12Å; Y478-H482 AromaticContact CD2-CG 3.86Å; Y478-H482 HydrophobicContact CE2-CB 3.69Å; Y478-H482 AromaticContact CE2-CD2 3.55Å; Y478-H482 AromaticContact CE2-CG 3.55Å; Y478-H482 WeakPolarHBondContact O-CB 3.33Å; Y478-H482 PolarHBondContact O-N 3.44Å; H482-F484 PolarHBondContact O-N 2.98Å; H482-F484 VanDerWaalsContact O-N 3.09Å; H482-S488 PolarHBondContact ND1-OG 3.44Å
483	K	79.6	Confident	84.7	Confident	2 Å²	2	22.6 Å²	22.6	1%	0.009	11%	0.109	C	C	.	.	S	Bend	trans	-56.7	-26.9	-179.9	-176.5	152.8	178.5	172	0	114.8	L160 F178 L181 S191 L479	L160-K483 HydrophobicContact CD2-CG 4.26Å; L160-K483 WeakPolarHBondContact CD2-O 3.34Å; F178-K483 VanDerWaalsContact CD1-O 3.25Å; F178-K483 WeakPolarHBondContact CD1-O 3.06Å; F178-K483 WeakPolarHBondContact CE1-O 3.3Å; L181-K483 HydrophobicContact CB-CD 4.4Å; L181-K483 VanDerWaalsContact CD2-CA 3.49Å; L181-K483 HydrophobicContact CD2-CB 3.6Å; L181-K483 HydrophobicContact CD2-CD 3.99Å; L181-K483 HydrophobicContact CD2-CG 3.66Å; L181-K483 WeakPolarHBondContact O-CE 3.41Å; L181-K483 PolarHBondContact O-NZ 3.04Å; S191-K483 WeakPolarHBondContact OG-CD 3.28Å; L479-K483 WeakPolarHBondContact O-CB 3.39Å
484	F	82.9	Confident	85.3	Confident	2 Å²	2	21.5 Å²	21.5	1%	0.009	10%	0.103	C	C	.	.	S	Bend	trans	-117.8	123.5	177.9	-56.9	-86.1	0	0	0	110.1	V158 L160 F192 H482 F486 F487 S488	V158-F484 HydrophobicContact CB-CE1 4.07Å; V158-F484 HydrophobicContact CG1-CD1 3.89Å; V158-F484 HydrophobicContact CG1-CE1 3.61Å; L160-F484 HydrophobicContact CD2-CD1 3.52Å; L160-F484 HydrophobicContact CD2-CE1 3.53Å; L160-F484 HydrophobicContact CD2-CG 4.39Å; L160-F484 HydrophobicContact CD2-CZ 4.4Å; F192-F484 HydrophobicContact CB-CD2 4.45Å; F192-F484 HydrophobicContact CB-CE2 3.58Å; F192-F484 HydrophobicContact CB-CZ 3.76Å; F192-F484 HydrophobicContact CD2-CD2 4.33Å; F192-F484 HydrophobicContact CD2-CE1 4.21Å; F192-F484 HydrophobicContact CD2-CE2 4.04Å; F192-F484 AromaticContact CD2-CZ 3.97Å; F192-F484 HydrophobicContact CD2-CZ 3.97Å; F192-F484 HydrophobicContact CG-CE2 4.32Å; F192-F484 HydrophobicContact CG-CZ 4.36Å; H482-F484 PolarHBondContact O-N 2.98Å; H482-F484 VanDerWaalsContact O-N 3.09Å; F484-F486 VanDerWaalsContact C-N 3.31Å; F484-F486 HydrophobicContact CB-CD1 4.08Å; F484-F486 HydrophobicContact CB-CE1 3.56Å; F484-F486 HydrophobicContact CB-CE2 4.24Å; F484-F486 HydrophobicContact CB-CZ 3.61Å; F484-F486 AromaticContact CD1-CE1 3.77Å; F484-F486 HydrophobicContact CD1-CE1 3.77Å; F484-F486 AromaticContact CD1-CZ 3.9Å; F484-F486 HydrophobicContact CD1-CZ 3.9Å; F484-F486 AromaticContact CG-CE1 3.98Å; F484-F486 HydrophobicContact CG-CE1 3.98Å; F484-F486 AromaticContact CG-CZ 3.86Å; F484-F486 HydrophobicContact CG-CZ 3.86Å; F484-F486 PolarHBondContact O-N 3.34Å; F484-F487 HydrophobicContact CB-CD2 3.76Å; F484-F487 HydrophobicContact CB-CE2 4.48Å; F484-F487 HydrophobicContact CD2-CD2 4.05Å; F484-F487 HydrophobicContact CD2-CE2 4.26Å; F484-F487 HydrophobicContact CG-CD2 4.17Å; F484-F487 HydrophobicContact CG-CE2 4.48Å; F484-F487 PolarHBondContact O-N 2.99Å; F484-S488 PolarHBondContact O-N 2.89Å
485	W	81.6	Confident	85.7	Confident	69 Å²	69	20.2 Å²	20.2	26%	0.261	10%	0.095	S	C	.	.	H	α-helix	trans	-60.6	-37.4	-176.9	69.7	-91.3	0	0	0	112.7	F178 I334 G337 F487 S488 A489	F178-W485 HydrophobicContact CZ-CB 4.4Å; I334-W485 WeakPolarHBondContact O-CZ3 3.43Å; G337-W485 VanDerWaalsContact CA-O 3.28Å; G337-W485 WeakPolarHBondContact CA-O 3.43Å; W485-F487 PolarHBondContact O-N 3.1Å; W485-S488 WeakPolarHBondContact O-CB 3.11Å; W485-S488 PolarHBondContact O-N 3.48Å; W485-A489 PolarHBondContact O-N 2.62Å
486	F	85.5	Confident	86.1	Confident	72 Å²	72	24.7 Å²	24.7	32%	0.316	11%	0.112	S	C	.	.	H	α-helix	trans	-69.1	-34	-178.2	59.6	-97	0	0	0	113	V158 F192 F484 A489 A490	V158-F486 HydrophobicContact CG1-CE1 4.37Å; F192-F486 HydrophobicContact CD2-CZ 4.23Å; F192-F486 HydrophobicContact CE2-CE2 4.24Å; F192-F486 AromaticContact CE2-CZ 3.82Å; F192-F486 HydrophobicContact CE2-CZ 3.82Å; F484-F486 VanDerWaalsContact C-N 3.31Å; F484-F486 HydrophobicContact CB-CD1 4.08Å; F484-F486 HydrophobicContact CB-CE1 3.56Å; F484-F486 HydrophobicContact CB-CE2 4.24Å; F484-F486 HydrophobicContact CB-CZ 3.61Å; F484-F486 AromaticContact CD1-CE1 3.77Å; F484-F486 HydrophobicContact CD1-CE1 3.77Å; F484-F486 AromaticContact CD1-CZ 3.9Å; F484-F486 HydrophobicContact CD1-CZ 3.9Å; F484-F486 AromaticContact CG-CE1 3.98Å; F484-F486 HydrophobicContact CG-CE1 3.98Å; F484-F486 AromaticContact CG-CZ 3.86Å; F484-F486 HydrophobicContact CG-CZ 3.86Å; F484-F486 PolarHBondContact O-N 3.34Å; F486-A489 PolarHBondContact O-N 2.92Å; F486-A490 PolarHBondContact O-N 3.46Å
487	F	89.2	Confident	86.6	Confident	13 Å²	13	24.6 Å²	24.6	6%	0.057	12%	0.122	C	C	.	.	H	α-helix	trans	-66.1	-43.1	171.9	-76.7	-55.7	0	0	0	110.2	F192 S195 S196 L199 F484 W485 A489 A490 Y491	F192-F487 AromaticContact CD2-CE2 3.67Å; F192-F487 HydrophobicContact CD2-CE2 3.67Å; F192-F487 HydrophobicContact CD2-CZ 4.21Å; F192-F487 AromaticContact CE2-CE2 3.76Å; F192-F487 HydrophobicContact CE2-CE2 3.76Å; F192-F487 AromaticContact CE2-CZ 3.92Å; F192-F487 HydrophobicContact CE2-CZ 3.92Å; F192-F487 HydrophobicContact CG-CE2 4.3Å; F192-F487 HydrophobicContact CZ-CE2 4.45Å; F192-F487 HydrophobicContact CZ-CZ 4.19Å; S195-F487 VanDerWaalsContact CB-CE2 3.46Å; S196-F487 WeakPolarHBondContact OG-CZ 3.43Å; L199-F487 HydrophobicContact CD2-CE1 4.3Å; F484-F487 HydrophobicContact CB-CD2 3.76Å; F484-F487 HydrophobicContact CB-CE2 4.48Å; F484-F487 HydrophobicContact CD2-CD2 4.05Å; F484-F487 HydrophobicContact CD2-CE2 4.26Å; F484-F487 HydrophobicContact CG-CD2 4.17Å; F484-F487 HydrophobicContact CG-CE2 4.48Å; F484-F487 PolarHBondContact O-N 2.99Å; W485-F487 PolarHBondContact O-N 3.1Å; F487-A489 VanDerWaalsContact C-N 3.31Å; F487-A489 PolarHBondContact O-N 2.91Å; F487-A490 WeakPolarHBondContact O-CB 3.05Å; F487-A490 PolarHBondContact O-N 2.58Å; F487-A490 VanDerWaalsContact O-N 3.14Å; F487-Y491 HydrophobicContact CB-CE2 3.83Å; F487-Y491 WeakPolarHBondContact O-CD2 3.47Å; F487-Y491 WeakPolarHBondContact O-CE2 3.31Å; F487-Y491 VanDerWaalsContact O-CG 3.23Å; F487-Y491 PolarHBondContact O-N 3.44Å
488	S	85.6	Confident	87.2	Confident	2 Å²	2	24.7 Å²	24.7	1%	0.014	12%	0.122	C	C	.	.	H	α-helix	trans	-57.8	-42.1	174.8	-62	0	0	0	0	112.4	G337 H482 F484 W485 Y491 Y492	G337-S488 WeakPolarHBondContact O-CB 3.48Å; H482-S488 PolarHBondContact ND1-OG 3.44Å; F484-S488 PolarHBondContact O-N 2.89Å; W485-S488 WeakPolarHBondContact O-CB 3.11Å; W485-S488 PolarHBondContact O-N 3.48Å; S488-Y491 PolarHBondContact O-N 3.35Å; S488-Y492 PolarHBondContact O-N 3.02Å
489	A	88.4	Confident	87.9	Confident	9 Å²	9	24.5 Å²	24.5	7%	0.074	12%	0.122	C	C	.	.	H	α-helix	trans	-63.1	-45.3	173.4	0	0	0	0	0	112.4	F338 W485 F486 F487 Y491 Y492 F493	F338-A489 HydrophobicContact CD2-CB 4.43Å; W485-A489 PolarHBondContact O-N 2.62Å; F486-A489 PolarHBondContact O-N 2.92Å; F487-A489 VanDerWaalsContact C-N 3.31Å; F487-A489 PolarHBondContact O-N 2.91Å; A489-Y491 VanDerWaalsContact C-N 3.31Å; A489-Y491 PolarHBondContact O-N 3.06Å; A489-Y492 WeakPolarHBondContact O-CB 3.35Å; A489-Y492 PolarHBondContact O-N 3.22Å; A489-F493 WeakPolarHBondContact O-CD2 3.31Å; A489-F493 PolarHBondContact O-N 2.92Å
490	A	92.2	Very high	88.8	Confident	34 Å²	34	25.4 Å²	25.4	28%	0.281	13%	0.134	S	C	.	.	H	α-helix	trans	-60.3	-41.8	177.7	0	0	0	0	0	111.8	L199 F486 F487 F493 G494	L199-A490 HydrophobicContact CD1-CB 3.78Å; F486-A490 PolarHBondContact O-N 3.46Å; F487-A490 WeakPolarHBondContact O-CB 3.05Å; F487-A490 PolarHBondContact O-N 2.58Å; F487-A490 VanDerWaalsContact O-N 3.14Å; A490-F493 PolarHBondContact O-N 3.48Å; A490-G494 PolarHBondContact O-N 2.89Å
491	Y	91.6	Very high	89.7	Confident	0 Å²	0	27.6 Å²	27.6	0%	0	15%	0.147	C	C	.	.	H	α-helix	trans	-66.7	-35.3	176.6	-60.5	-46	0	0	0	113.6	S195 T198 L199 M202 Y423 F487 S488 A489 G494 N495	S195-Y491 PolarHBondContact O-OH 3.42Å; T198-Y491 PolarHBondContact OG1-OH 3.3Å; L199-Y491 HydrophobicContact CB-CE1 4.35Å; L199-Y491 HydrophobicContact CD1-CD1 4.45Å; L199-Y491 HydrophobicContact CD1-CE1 4.22Å; M202-Y491 HydrophobicContact SD-CD1 3.69Å; Y423-Y491 HydrophobicContact CD1-CD1 4.4Å; Y423-Y491 HydrophobicContact CD1-CD2 4.37Å; Y423-Y491 HydrophobicContact CD1-CG 4.09Å; Y423-Y491 AromaticContact CD2-CD2 3.61Å; Y423-Y491 HydrophobicContact CD2-CD2 3.61Å; Y423-Y491 AromaticContact CD2-CE2 3.89Å; Y423-Y491 HydrophobicContact CD2-CE2 3.89Å; Y423-Y491 HydrophobicContact CD2-CG 4.17Å; Y423-Y491 HydrophobicContact CE1-CD1 4.36Å; Y423-Y491 HydrophobicContact CE1-CD2 4.06Å; Y423-Y491 AromaticContact CE1-CG 3.7Å; Y423-Y491 HydrophobicContact CE1-CG 3.7Å; Y423-Y491 AromaticContact CE2-CD2 3.15Å; Y423-Y491 HydrophobicContact CE2-CD2 3.15Å; Y423-Y491 AromaticContact CE2-CE2 3.86Å; Y423-Y491 HydrophobicContact CE2-CE2 3.86Å; Y423-Y491 AromaticContact CE2-CG 3.71Å; Y423-Y491 HydrophobicContact CE2-CG 3.71Å; Y423-Y491 HydrophobicContact CG-CD2 4.2Å; Y423-Y491 HydrophobicContact CG-CE2 4.48Å; Y423-Y491 HydrophobicContact CG-CG 4.35Å; Y423-Y491 AromaticContact CZ-CD2 3.46Å; Y423-Y491 VanDerWaalsContact CZ-CD2 3.46Å; Y423-Y491 AromaticContact CZ-CG 3.5Å; Y423-Y491 VanDerWaalsContact CZ-CG 3.5Å; Y423-Y491 WeakPolarHBondContact OH-CB 3.22Å; F487-Y491 HydrophobicContact CB-CE2 3.83Å; F487-Y491 WeakPolarHBondContact O-CD2 3.47Å; F487-Y491 WeakPolarHBondContact O-CE2 3.31Å; F487-Y491 VanDerWaalsContact O-CG 3.23Å; F487-Y491 PolarHBondContact O-N 3.44Å; S488-Y491 PolarHBondContact O-N 3.35Å; A489-Y491 VanDerWaalsContact C-N 3.31Å; A489-Y491 PolarHBondContact O-N 3.06Å; Y491-G494 PolarHBondContact O-N 3.31Å; Y491-N495 PolarHBondContact O-N 3.28Å
492	Y	91.4	Very high	90.5	Very high	15 Å²	15	27.7 Å²	27.7	6%	0.059	15%	0.147	C	C	.	.	H	α-helix	trans	-58.2	-48.9	174	170.3	-97.4	0	0	0	111.4	N324 K327 A328 F338 S488 A489 G494 N495 W496	N324-Y492 HydrophobicContact CB-CE2 4.07Å; K327-Y492 HydrophobicContact CB-CD2 4.08Å; K327-Y492 HydrophobicContact CB-CE2 3.71Å; K327-Y492 HydrophobicContact CD-CD2 3.95Å; K327-Y492 HydrophobicContact CD-CE2 4.41Å; A328-Y492 WeakPolarHBondContact CB-OH 3.47Å; F338-Y492 HydrophobicContact CB-CD2 4.27Å; F338-Y492 HydrophobicContact CB-CG 4.3Å; F338-Y492 HydrophobicContact CD1-CD1 4.29Å; F338-Y492 HydrophobicContact CD1-CD2 4.48Å; F338-Y492 HydrophobicContact CD1-CE1 4.2Å; F338-Y492 HydrophobicContact CD1-CE2 4.37Å; F338-Y492 HydrophobicContact CD1-CG 4.42Å; F338-Y492 AromaticContact CD2-CD1 3.7Å; F338-Y492 HydrophobicContact CD2-CD1 3.7Å; F338-Y492 HydrophobicContact CD2-CD2 4.49Å; F338-Y492 HydrophobicContact CD2-CE1 4.35Å; F338-Y492 AromaticContact CD2-CG 3.78Å; F338-Y492 HydrophobicContact CD2-CG 3.78Å; F338-Y492 HydrophobicContact CE1-CD1 4.18Å; F338-Y492 AromaticContact CE1-CE1 3.85Å; F338-Y492 HydrophobicContact CE1-CE1 3.85Å; F338-Y492 AromaticContact CE2-CD1 3.54Å; F338-Y492 HydrophobicContact CE2-CD1 3.54Å; F338-Y492 AromaticContact CE2-CE1 3.99Å; F338-Y492 HydrophobicContact CE2-CE1 3.99Å; F338-Y492 HydrophobicContact CE2-CG 4.12Å; F338-Y492 HydrophobicContact CG-CD1 4.07Å; F338-Y492 HydrophobicContact CG-CD2 4.2Å; F338-Y492 HydrophobicContact CG-CE1 4.44Å; F338-Y492 AromaticContact CG-CG 3.94Å; F338-Y492 HydrophobicContact CG-CG 3.94Å; F338-Y492 AromaticContact CZ-CD1 3.78Å; F338-Y492 HydrophobicContact CZ-CD1 3.78Å; F338-Y492 AromaticContact CZ-CE1 3.72Å; F338-Y492 HydrophobicContact CZ-CE1 3.72Å; S488-Y492 PolarHBondContact O-N 3.02Å; A489-Y492 WeakPolarHBondContact O-CB 3.35Å; A489-Y492 PolarHBondContact O-N 3.22Å; Y492-G494 VanDerWaalsContact C-N 3.31Å; Y492-G494 PolarHBondContact O-N 2.93Å; Y492-N495 WeakPolarHBondContact O-CB 3.4Å; Y492-N495 PolarHBondContact O-N 3.34Å; Y492-W496 AromaticContact CE1-CD1 3.87Å; Y492-W496 AromaticContact CE1-NE1 3.74Å; Y492-W496 AromaticContact CE2-NE1 3.76Å; Y492-W496 AromaticContact CZ-CD1 3.82Å; Y492-W496 AromaticContact CZ-NE1 3.25Å; Y492-W496 VanDerWaalsContact CZ-NE1 3.25Å; Y492-W496 PolarHBondContact O-N 2.88Å; Y492-W496 PolarHBondContact OH-NE1 3.38Å
493	F	93.1	Very high	91.3	Very high	112 Å²	112	32.3 Å²	32.3	49%	0.491	17%	0.171	S	C	.	.	H	α-helix	trans	-65.3	-36.2	174.8	-68.6	-66.3	0	0	0	112.3	F338 A489 A490 N495 W496 A497	F338-F493 HydrophobicContact CE2-CE2 4.24Å; F338-F493 HydrophobicContact CE2-CZ 4.3Å; F338-F493 HydrophobicContact CZ-CZ 4.38Å; A489-F493 WeakPolarHBondContact O-CD2 3.31Å; A489-F493 PolarHBondContact O-N 2.92Å; A490-F493 PolarHBondContact O-N 3.48Å; F493-N495 VanDerWaalsContact C-N 3.31Å; F493-N495 PolarHBondContact O-N 2.93Å; F493-W496 WeakPolarHBondContact O-CB 3.46Å; F493-W496 PolarHBondContact O-N 3.32Å; F493-A497 PolarHBondContact O-N 3.41Å
494	G	94.6	Very high	92	Very high	5 Å²	5	37.5 Å²	37.5	5%	0.052	20%	0.198	C	C	.	.	H	α-helix	trans	-59.6	-37.7	173.6	0	0	0	0	0	113.8	M202 A490 Y491 Y492 W496 A497 F498	M202-G494 VanDerWaalsContact SD-CA 3.59Å; A490-G494 PolarHBondContact O-N 2.89Å; Y491-G494 PolarHBondContact O-N 3.31Å; Y492-G494 VanDerWaalsContact C-N 3.31Å; Y492-G494 PolarHBondContact O-N 2.93Å; G494-W496 VanDerWaalsContact C-N 3.35Å; G494-W496 PolarHBondContact O-N 3.29Å; G494-A497 PolarHBondContact O-N 2.79Å; G494-F498 WeakPolarHBondContact O-CB 3.49Å; G494-F498 PolarHBondContact O-N 2.71Å
495	N	94.4	Very high	92.4	Very high	2 Å²	2	37.6 Å²	37.6	1%	0.011	20%	0.2	C	C	.	.	H	α-helix	trans	-62.3	-41.2	174.6	-71.4	-22	0	0	0	111.8	N324 S427 Y491 Y492 F493 F498 L499	N324-N495 VanDerWaalsContact ND2-CB 3.35Å; N324-N495 WeakPolarHBondContact ND2-CB 3.07Å; N324-N495 PolarHBondContact OD1-ND2 3.45Å; N324-N495 VanDerWaalsContact OD1-ND2 3.12Å; S427-N495 WeakPolarHBondContact CB-ND2 3Å; S427-N495 PolarHBondContact OG-ND2 2.92Å; S427-N495 VanDerWaalsContact OG-ND2 3.09Å; Y491-N495 PolarHBondContact O-N 3.28Å; Y492-N495 WeakPolarHBondContact O-CB 3.4Å; Y492-N495 PolarHBondContact O-N 3.34Å; F493-N495 VanDerWaalsContact C-N 3.31Å; F493-N495 PolarHBondContact O-N 2.93Å; N495-F498 WeakPolarHBondContact O-CB 3.5Å; N495-F498 PolarHBondContact O-N 2.93Å; N495-L499 WeakPolarHBondContact O-CG 3.44Å; N495-L499 PolarHBondContact O-N 3.38Å
496	W	95.2	Very high	92.9	Very high	95 Å²	95	36.9 Å²	36.9	36%	0.36	20%	0.201	S	C	.	.	H	α-helix	trans	-63.7	-42.5	174.2	-78.2	109.3	0	0	0	112.1	F321 N324 Y492 F493 G494 F498 L499 G500	F321-W496 HydrophobicContact CD2-CH2 4Å; F321-W496 AromaticContact CD2-CZ3 3.95Å; F321-W496 HydrophobicContact CD2-CZ3 3.95Å; F321-W496 AromaticContact CE2-CH2 3.76Å; F321-W496 HydrophobicContact CE2-CH2 3.76Å; F321-W496 AromaticContact CE2-CZ3 3.86Å; F321-W496 HydrophobicContact CE2-CZ3 3.86Å; N324-W496 HydrophobicContact CB-CZ2 4.22Å; Y492-W496 AromaticContact CE1-CD1 3.87Å; Y492-W496 AromaticContact CE1-NE1 3.74Å; Y492-W496 AromaticContact CE2-NE1 3.76Å; Y492-W496 AromaticContact CZ-CD1 3.82Å; Y492-W496 AromaticContact CZ-NE1 3.25Å; Y492-W496 VanDerWaalsContact CZ-NE1 3.25Å; Y492-W496 PolarHBondContact O-N 2.88Å; Y492-W496 PolarHBondContact OH-NE1 3.38Å; F493-W496 WeakPolarHBondContact O-CB 3.46Å; F493-W496 PolarHBondContact O-N 3.32Å; G494-W496 VanDerWaalsContact C-N 3.35Å; G494-W496 PolarHBondContact O-N 3.29Å; W496-F498 VanDerWaalsContact C-N 3.32Å; W496-F498 PolarHBondContact O-N 3.34Å; W496-L499 HydrophobicContact CE3-CD1 4.06Å; W496-L499 HydrophobicContact CZ3-CD1 4.32Å; W496-L499 PolarHBondContact O-N 2.98Å; W496-G500 PolarHBondContact O-N 3.48Å
497	A	96.6	Very high	93.2	Very high	45 Å²	45	37.7 Å²	37.7	37%	0.372	21%	0.211	S	C	.	.	H	α-helix	trans	-61.5	-41.5	174.4	0	0	0	0	0	111.8	I206 F493 G494 L499 G500 V501	I206-A497 HydrophobicContact CD1-CB 4.02Å; F493-A497 PolarHBondContact O-N 3.41Å; G494-A497 PolarHBondContact O-N 2.79Å; A497-L499 PolarHBondContact O-N 3.2Å; A497-G500 PolarHBondContact O-N 3.4Å; A497-V501 WeakPolarHBondContact O-CG2 3.22Å; A497-V501 PolarHBondContact O-N 3.28Å
498	F	96.6	Very high	93.3	Very high	4 Å²	4	40.4 Å²	40.4	2%	0.018	23%	0.229	C	C	.	.	H	α-helix	trans	-59.5	-45.5	175.7	-175.6	-89.9	0	0	0	112.1	I206 T209 A210 M213 I317 L320 F374 M424 G494 N495 W496 G500 V501 F502	I206-F498 HydrophobicContact CG1-CB 4.02Å; I206-F498 HydrophobicContact CG1-CD2 4.26Å; T209-F498 HydrophobicContact CG2-CE2 4.3Å; T209-F498 HydrophobicContact CG2-CZ 4.41Å; A210-F498 HydrophobicContact CB-CD2 3.79Å; A210-F498 HydrophobicContact CB-CE2 3.77Å; A210-F498 HydrophobicContact CB-CG 4.23Å; A210-F498 HydrophobicContact CB-CZ 4.21Å; M213-F498 HydrophobicContact CE-CD1 4.43Å; M213-F498 HydrophobicContact CE-CE1 3.27Å; M213-F498 HydrophobicContact CE-CE2 4.42Å; M213-F498 HydrophobicContact CE-CZ 3.26Å; M213-F498 HydrophobicContact SD-CE1 4.29Å; M213-F498 HydrophobicContact SD-CZ 3.9Å; I317-F498 HydrophobicContact CD1-CE1 4.45Å; L320-F498 HydrophobicContact CD1-CD1 4.05Å; L320-F498 HydrophobicContact CD1-CE1 4.01Å; F374-F498 HydrophobicContact CE1-CZ 4.46Å; M424-F498 HydrophobicContact SD-CE1 4.32Å; M424-F498 HydrophobicContact SD-CE2 4.17Å; M424-F498 HydrophobicContact SD-CZ 3.96Å; G494-F498 WeakPolarHBondContact O-CB 3.49Å; G494-F498 PolarHBondContact O-N 2.71Å; N495-F498 WeakPolarHBondContact O-CB 3.5Å; N495-F498 PolarHBondContact O-N 2.93Å; W496-F498 VanDerWaalsContact C-N 3.32Å; W496-F498 PolarHBondContact O-N 3.34Å; F498-G500 PolarHBondContact O-N 3.16Å; F498-V501 PolarHBondContact O-N 3.24Å; F498-F502 WeakPolarHBondContact O-CB 3.41Å; F498-F502 PolarHBondContact O-N 2.9Å
499	L	96	Very high	93.4	Very high	12 Å²	12	40.7 Å²	40.7	6%	0.063	23%	0.231	C	C	.	.	H	α-helix	trans	-59.6	-45.3	174.4	-68.8	171.4	0	0	0	111.5	I317 L320 F321 N495 W496 A497 F502 L503	I317-L499 HydrophobicContact CB-CD2 4.37Å; I317-L499 HydrophobicContact CD1-CD2 3.72Å; I317-L499 HydrophobicContact CG2-CD2 3.86Å; L320-L499 HydrophobicContact CB-CD2 4.16Å; F321-L499 HydrophobicContact CB-CD1 4.28Å; F321-L499 HydrophobicContact CD2-CD1 4.34Å; N495-L499 WeakPolarHBondContact O-CG 3.44Å; N495-L499 PolarHBondContact O-N 3.38Å; W496-L499 HydrophobicContact CE3-CD1 4.06Å; W496-L499 HydrophobicContact CZ3-CD1 4.32Å; W496-L499 PolarHBondContact O-N 2.98Å; A497-L499 PolarHBondContact O-N 3.2Å; L499-F502 PolarHBondContact O-N 3.28Å; L499-L503 WeakPolarHBondContact O-CG 3.37Å; L499-L503 PolarHBondContact O-N 2.93Å; L499-L503 VanDerWaalsContact O-N 3.15Å
500	G	95.9	Very high	93.3	Very high	30 Å²	30	43.4 Å²	43.4	31%	0.309	25%	0.249	S	C	.	.	H	α-helix	trans	-61.7	-48.2	178.2	0	0	0	0	0	113	W496 A497 F498 F502 L503 I504	W496-G500 PolarHBondContact O-N 3.48Å; A497-G500 PolarHBondContact O-N 3.4Å; F498-G500 PolarHBondContact O-N 3.16Å; G500-F502 VanDerWaalsContact C-N 3.32Å; G500-F502 PolarHBondContact O-N 3.21Å; G500-L503 PolarHBondContact O-N 3.18Å; G500-I504 WeakPolarHBondContact O-CG1 3.43Å; G500-I504 PolarHBondContact O-N 3.48Å
501	V	95.6	Very high	93.1	Very high	47 Å²	47	46.9 Å²	46.9	29%	0.285	27%	0.27	S	S	.	.	H	α-helix	trans	-66.2	-34.7	178.8	176.8	0	0	0	0	111.6	I206 A210 A497 F498 I504 G505	I206-V501 HydrophobicContact CG2-CB 4.22Å; I206-V501 HydrophobicContact CG2-CG2 3.7Å; I206-V501 WeakPolarHBondContact O-CG1 3.48Å; A210-V501 HydrophobicContact CB-CB 4.16Å; A210-V501 HydrophobicContact CB-CG1 4.01Å; A497-V501 WeakPolarHBondContact O-CG2 3.22Å; A497-V501 PolarHBondContact O-N 3.28Å; F498-V501 PolarHBondContact O-N 3.24Å; V501-I504 PolarHBondContact O-N 2.76Å; V501-G505 PolarHBondContact O-N 3.01Å
502	F	95.6	Very high	92.7	Very high	5 Å²	5	51.8 Å²	51.8	2%	0.022	29%	0.291	C	S	.	.	H	α-helix	trans	-59.6	-47.6	172.9	171.7	-95.2	0	0	0	111.8	A210 M213 A313 I317 F498 L499 G500 G505 L506	A210-F502 HydrophobicContact CB-CB 4.38Å; M213-F502 HydrophobicContact CB-CD2 4.04Å; M213-F502 HydrophobicContact CB-CE2 4.03Å; M213-F502 HydrophobicContact CE-CD2 3.71Å; M213-F502 HydrophobicContact CE-CE2 4.27Å; M213-F502 HydrophobicContact CE-CG 4.39Å; A313-F502 HydrophobicContact CB-CE2 4.08Å; A313-F502 HydrophobicContact CB-CZ 4.18Å; I317-F502 HydrophobicContact CB-CE1 4.45Å; I317-F502 HydrophobicContact CD1-CB 3.79Å; I317-F502 HydrophobicContact CD1-CD1 3.47Å; I317-F502 VanDerWaalsContact CD1-CD1 3.47Å; I317-F502 HydrophobicContact CD1-CD2 4.01Å; I317-F502 HydrophobicContact CD1-CE1 4.03Å; I317-F502 HydrophobicContact CD1-CE2 4.49Å; I317-F502 HydrophobicContact CD1-CG 3.45Å; I317-F502 VanDerWaalsContact CD1-CG 3.45Å; I317-F502 HydrophobicContact CD1-CZ 4.49Å; I317-F502 HydrophobicContact CG1-CD1 3.61Å; I317-F502 HydrophobicContact CG1-CD2 4.27Å; I317-F502 HydrophobicContact CG1-CE1 3.6Å; I317-F502 HydrophobicContact CG1-CE2 4.25Å; I317-F502 HydrophobicContact CG1-CG 3.95Å; I317-F502 HydrophobicContact CG1-CZ 3.92Å; I317-F502 HydrophobicContact CG2-CD1 4.36Å; I317-F502 HydrophobicContact CG2-CE1 4.4Å; F498-F502 WeakPolarHBondContact O-CB 3.41Å; F498-F502 PolarHBondContact O-N 2.9Å; L499-F502 PolarHBondContact O-N 3.28Å; G500-F502 VanDerWaalsContact C-N 3.32Å; G500-F502 PolarHBondContact O-N 3.21Å; F502-G505 PolarHBondContact O-N 3.19Å; F502-L506 HydrophobicContact CE1-CD1 3.91Å; F502-L506 HydrophobicContact CZ-CD1 3.83Å; F502-L506 WeakPolarHBondContact O-CB 3.42Å; F502-L506 PolarHBondContact O-N 3.22Å
503	L	94.8	Very high	91.8	Very high	103 Å²	103	53.8 Å²	53.8	54%	0.539	32%	0.316	S	S	.	.	H	α-helix	trans	-62.1	-45.7	178.9	-69	175.3	0	0	0	111.7	L499 G500 G505 L506 V507	L499-L503 WeakPolarHBondContact O-CG 3.37Å; L499-L503 PolarHBondContact O-N 2.93Å; L499-L503 VanDerWaalsContact O-N 3.15Å; G500-L503 PolarHBondContact O-N 3.18Å; L503-G505 VanDerWaalsContact C-N 3.34Å; L503-G505 PolarHBondContact O-N 3.08Å; L503-L506 PolarHBondContact O-N 3.33Å; L503-V507 WeakPolarHBondContact O-CG2 3.3Å; L503-V507 PolarHBondContact O-N 3.22Å
504	I	94.3	Very high	91.1	Very high	111 Å²	111	54.6 Å²	54.6	57%	0.569	32%	0.32	S	S	*	.	H	α-helix	trans	-59.6	-47.4	175	-65	166.6	0	0	0	110.1	G500 V501 L506 V507 V508	G500-I504 WeakPolarHBondContact O-CG1 3.43Å; G500-I504 PolarHBondContact O-N 3.48Å; V501-I504 PolarHBondContact O-N 2.76Å; I504-L506 VanDerWaalsContact C-N 3.28Å; I504-L506 PolarHBondContact O-N 3.35Å; I504-V507 PolarHBondContact O-N 2.98Å; I504-V508 HydrophobicContact CG2-CG2 4.25Å; I504-V508 WeakPolarHBondContact O-CB 3.3Å; I504-V508 VanDerWaalsContact O-CG2 3.31Å; I504-V508 WeakPolarHBondContact O-CG2 3.48Å; I504-V508 PolarHBondContact O-N 3.49Å
505	G	92	Very high	90.1	Very high	4 Å²	4	57.5 Å²	57.5	4%	0.041	33%	0.331	C	S	.	.	H	α-helix	trans	-61.4	-35	178.4	0	0	0	0	0	113.1	S214 V501 F502 L503 S509	S214-G505 PolarHBondContact OG-O 2.99Å; V501-G505 PolarHBondContact O-N 3.01Å; F502-G505 PolarHBondContact O-N 3.19Å; L503-G505 VanDerWaalsContact C-N 3.34Å; L503-G505 PolarHBondContact O-N 3.08Å; G505-S509 WeakPolarHBondContact O-CB 3.48Å; G505-S509 PolarHBondContact O-N 3.38Å; G505-S509 PolarHBondContact O-OG 3.5Å
506	L	92.1	Very high	88.6	Confident	55 Å²	55	58.5 Å²	58.5	29%	0.288	34%	0.338	S	S	.	.	H	α-helix	trans	-67.2	-46.6	174.9	-171.2	147.9	0	0	0	111.1	S214 F502 L503 I504 S509 C510	S214-L506 PolarHBondContact OG-N 2.96Å; F502-L506 HydrophobicContact CE1-CD1 3.91Å; F502-L506 HydrophobicContact CZ-CD1 3.83Å; F502-L506 WeakPolarHBondContact O-CB 3.42Å; F502-L506 PolarHBondContact O-N 3.22Å; L503-L506 PolarHBondContact O-N 3.33Å; I504-L506 VanDerWaalsContact C-N 3.28Å; I504-L506 PolarHBondContact O-N 3.35Å; L506-S509 PolarHBondContact O-N 3.49Å; L506-C510 VanDerWaalsContact O-CB 3.31Å; L506-C510 WeakPolarHBondContact O-CB 3.12Å; L506-C510 PolarHBondContact O-N 3.49Å; L506-C510 PolarHBondContact O-SG 2.88Å
507	V	92.6	Very high	87.2	Confident	88 Å²	88	55 Å²	55	53%	0.533	33%	0.327	S	S	.	.	H	α-helix	trans	-60.3	-51.1	175.2	174.3	0	0	0	0	110.8	L503 I504 S509 C510 C511	L503-V507 WeakPolarHBondContact O-CG2 3.3Å; L503-V507 PolarHBondContact O-N 3.22Å; I504-V507 PolarHBondContact O-N 2.98Å; V507-S509 VanDerWaalsContact C-N 3.34Å; V507-S509 PolarHBondContact O-N 3.25Å; V507-C510 WeakPolarHBondContact O-CB 3.44Å; V507-C510 PolarHBondContact O-N 2.85Å; V507-C510 VanDerWaalsContact O-N 3.16Å; V507-C511 PolarHBondContact O-N 3.4Å; V507-C511 PolarHBondContact O-SG 3.42Å; V507-C511 VanDerWaalsContact O-SG 3.33Å
508	V	90.2	Very high	85.3	Confident	70 Å²	70	52.9 Å²	52.9	42%	0.424	31%	0.309	S	S	.	.	H	α-helix	trans	-59	-45.4	179.1	170.8	0	0	0	0	111.1	I504 C510 C511 K512	I504-V508 HydrophobicContact CG2-CG2 4.25Å; I504-V508 WeakPolarHBondContact O-CB 3.3Å; I504-V508 VanDerWaalsContact O-CG2 3.31Å; I504-V508 WeakPolarHBondContact O-CG2 3.48Å; I504-V508 PolarHBondContact O-N 3.49Å; V508-C510 VanDerWaalsContact C-N 3.32Å; V508-C510 PolarHBondContact O-N 2.97Å; V508-C511 PolarHBondContact O-N 3.34Å; V508-K512 WeakPolarHBondContact O-CB 3.42Å; V508-K512 PolarHBondContact O-N 3.33Å
509	S	87.8	Confident	83.4	Confident	9 Å²	9	57.4 Å²	57.4	6%	0.063	33%	0.331	C	S	.	.	H	α-helix	trans	-68.8	-30.5	179.7	-64.4	0	0	0	0	112.4	A215 K222 G505 L506 V507	A215-S509 WeakPolarHBondContact CA-OG 3.3Å; K222-S509 PolarHBondContact NZ-O 2.92Å; G505-S509 WeakPolarHBondContact O-CB 3.48Å; G505-S509 PolarHBondContact O-N 3.38Å; G505-S509 PolarHBondContact O-OG 3.5Å; L506-S509 PolarHBondContact O-N 3.49Å; V507-S509 VanDerWaalsContact C-N 3.34Å; V507-S509 PolarHBondContact O-N 3.25Å
510	C	87.5	Confident	81.3	Confident	65 Å²	65	59.3 Å²	59.3	44%	0.439	35%	0.353	S	S	.	.	H	α-helix	trans	-69.3	-40.1	172.1	-78	0	0	0	0	111.9	K222 L506 V507 V508	K222-C510 VanDerWaalsContact NZ-C 3.33Å; K222-C510 PolarHBondContact NZ-O 2.85Å; L506-C510 VanDerWaalsContact O-CB 3.31Å; L506-C510 WeakPolarHBondContact O-CB 3.12Å; L506-C510 PolarHBondContact O-N 3.49Å; L506-C510 PolarHBondContact O-SG 2.88Å; V507-C510 WeakPolarHBondContact O-CB 3.44Å; V507-C510 PolarHBondContact O-N 2.85Å; V507-C510 VanDerWaalsContact O-N 3.16Å; V508-C510 VanDerWaalsContact C-N 3.32Å; V508-C510 PolarHBondContact O-N 2.97Å
511	C	87.3	Confident	79	Confident	107 Å²	107	59.4 Å²	59.4	72%	0.723	35%	0.347	S	S	*	.	H	α-helix	trans	-75.6	-28.1	178.1	-64	0	0	0	0	113.6	V507 V508 G513	V507-C511 PolarHBondContact O-N 3.4Å; V507-C511 PolarHBondContact O-SG 3.42Å; V507-C511 VanDerWaalsContact O-SG 3.33Å; V508-C511 PolarHBondContact O-N 3.34Å; C511-G513 PolarHBondContact O-N 2.89Å
512	K	83.4	Confident	76.4	Confident	104 Å²	104	59 Å²	59	45%	0.452	34%	0.344	S	S	.	.	S	Bend	trans	-67	130.1	-177.7	-165.1	166.4	-176.5	166.1	0	112	K222 V508	K222-K512 PolarHBondContact NZ-O 2.78Å; V508-K512 WeakPolarHBondContact O-CB 3.42Å; V508-K512 PolarHBondContact O-N 3.33Å
513	G	72.8	Confident	74	Confident	57 Å²	57	61.6 Å²	61.6	59%	0.588	36%	0.356	S	S	*	.	P	Polyproline II helix	trans	-65	173.2	179.1	0	0	0	0	0	114.4	C511	C511-G513 PolarHBondContact O-N 2.89Å
514	K	77.1	Confident	71.4	Confident	129 Å²	129	62.1 Å²	62.1	56%	0.561	36%	0.355	S	S	*	.	P	Polyproline II helix	trans	-64.3	135.9	172.6	-66.9	179.3	-178.8	174.3	0	109.6	K222 R225	K222-K514 HydrophobicContact CB-CG 4.41Å; R225-K514 HydrophobicContact CG-CB 3.88Å
515	K	74.7	Confident	68.9	Low	66 Å²	66	57.9 Å²	57.9	29%	0.287	34%	0.336	S	S	.	.	B	Isolated β-bridge	trans	-69.5	148.2	173.6	-65.1	-168.2	-177	-172	0	110.7	R225 N384	R225-K515 PolarHBondContact N-O 3.35Å; R225-K515 VanDerWaalsContact N-O 3.09Å; N384-K515 PolarHBondContact OD1-NZ 2.85Å
516	S	62.7	Low	66.5	Low	22 Å²	22	63.6 Å²	63.6	15%	0.154	37%	0.365	C	S	.	.	P	Polyproline II helix	trans	-69.4	150.1	175.6	171.2	0	0	0	0	110.8	E230 R279 I518 E519	E230-S516 WeakPolarHBondContact OE1-CA 3.32Å; E230-S516 WeakPolarHBondContact OE1-CB 3.17Å; E230-S516 PolarHBondContact OE1-OG 2.9Å; E230-S516 PolarHBondContact OE2-OG 3.01Å; R279-S516 PolarHBondContact NH2-OG 3.46Å; R279-S516 VanDerWaalsContact NH2-OG 3.14Å; S516-I518 PolarHBondContact O-N 2.85Å; S516-I518 PolarHBondContact OG-N 3.15Å; S516-E519 PolarHBondContact N-OE2 2.95Å; S516-E519 PolarHBondContact O-N 3.24Å
517	V	65.2	Low	64.1	Low	23 Å²	23	65 Å²	65	14%	0.139	37%	0.372	C	S	.	.	S	Bend	trans	-64.2	-33.6	177.7	-177.5	0	0	0	0	110.4	R225 A227 E230 I286	R225-V517 HydrophobicContact CB-CG2 4.48Å; R225-V517 WeakPolarHBondContact O-CG2 3.45Å; A227-V517 HydrophobicContact CB-CG1 4.28Å; A227-V517 HydrophobicContact CB-CG2 4.35Å; E230-V517 PolarHBondContact OE1-N 2.84Å; E230-V517 WeakPolarHBondContact OE2-CB 3.28Å; E230-V517 PolarHBondContact OE2-N 3.07Å; I286-V517 HydrophobicContact CD1-CG1 4.18Å; I286-V517 HydrophobicContact CG2-CG1 3.75Å
518	I	57.8	Low	61.4	Low	0 Å²	0	64 Å²	64	0%	0	37%	0.369	C	S	.	.	G	3₁₀ helix	trans	-87.9	-15	-176.9	-28.7	178.2	0	0	0	112.3	R279 H282 L283 S516 G520 V521 D522	R279-I518 HydrophobicContact CG-CD1 3.17Å; R279-I518 VanDerWaalsContact NE-CD1 3.3Å; H282-I518 HydrophobicContact CB-CG2 4.48Å; L283-I518 HydrophobicContact CD1-CD1 3.62Å; L283-I518 HydrophobicContact CD2-CD1 3.39Å; L283-I518 HydrophobicContact CD2-CG1 3.42Å; L283-I518 VanDerWaalsContact CD2-CG1 3.42Å; L283-I518 HydrophobicContact CG-CD1 3.33Å; L283-I518 HydrophobicContact CG-CG1 3.93Å; S516-I518 PolarHBondContact O-N 2.85Å; S516-I518 PolarHBondContact OG-N 3.15Å; I518-G520 PolarHBondContact O-N 3.09Å; I518-V521 HydrophobicContact CG2-CB 4.17Å; I518-V521 CarbonylContact O-C 3.53Å; I518-V521 PolarHBondContact O-N 3.44Å; I518-D522 HydrophobicContact CG2-CB 3.96Å; I518-D522 WeakPolarHBondContact CG2-OD1 3.2Å; I518-D522 WeakPolarHBondContact CG2-OD2 3.44Å; I518-D522 WeakPolarHBondContact O-CB 3.41Å; I518-D522 PolarHBondContact O-N 3.46Å
519	E	56.5	Low	58.9	Low	99 Å²	99	65.4 Å²	65.4	46%	0.463	37%	0.374	S	S	.	.	G	3₁₀ helix	trans	-60.8	-17.1	171.5	-158.8	178.9	170.9	0	0	111.8	S516 E523	S516-E519 PolarHBondContact N-OE2 2.95Å; S516-E519 PolarHBondContact O-N 3.24Å; E519-E523 WeakPolarHBondContact O-CG 3.35Å
520	G	51.3	Low	56.5	Low	51 Å²	51	71.7 Å²	71.7	53%	0.526	41%	0.407	S	S	.	.	G	3₁₀ helix	trans	-90.8	-12.4	168.7	0	0	0	0	0	116	I518	I518-G520 PolarHBondContact O-N 3.09Å
521	V	48.3	Very low	53.9	Low	33 Å²	33	74.6 Å²	74.6	20%	0.2	42%	0.418	C	S	.	.	T	Hydrogen-bonded Turn	trans	-121.7	-38.1	-171	-177.8	0	0	0	0	113.3	I286 I518 E523 E524	I286-V521 HydrophobicContact CD1-CB 4.17Å; I286-V521 HydrophobicContact CD1-CG1 4.27Å; I286-V521 HydrophobicContact CD1-CG2 3.75Å; I518-V521 HydrophobicContact CG2-CB 4.17Å; I518-V521 CarbonylContact O-C 3.53Å; I518-V521 PolarHBondContact O-N 3.44Å; V521-E523 PolarHBondContact O-N 2.93Å; V521-E524 WeakPolarHBondContact O-CA 3.39Å; V521-E524 VanDerWaalsContact O-CB 3.26Å; V521-E524 WeakPolarHBondContact O-CB 3.41Å; V521-E524 PolarHBondContact O-N 3.4Å
522	D	41	Very low	51	Low	38 Å²	38	77.7 Å²	77.7	20%	0.203	42%	0.422	C	S	.	.	H	α-helix	trans	-59.6	-27.2	170.4	-80.9	-23.4	0	0	0	110.4	R279 I518 E524 S525	R279-D522 IonicContact CZ-OD2 3.59Å; R279-D522 IonicContact NH1-OD2 2.62Å; R279-D522 PolarHBondContact NH1-OD2 3.49Å; I518-D522 HydrophobicContact CG2-CB 3.96Å; I518-D522 WeakPolarHBondContact CG2-OD1 3.2Å; I518-D522 WeakPolarHBondContact CG2-OD2 3.44Å; I518-D522 WeakPolarHBondContact O-CB 3.41Å; I518-D522 PolarHBondContact O-N 3.46Å; D522-E524 PolarHBondContact O-N 3.28Å; D522-S525 PolarHBondContact O-OG 3.25Å
523	E	44.3	Very low	48.6	Very low	60 Å²	60	78.1 Å²	78.1	28%	0.28	44%	0.435	S	S	.	.	H	α-helix	trans	-71.3	-10.2	171.4	-63.2	-167.8	-175.1	0	0	114.4	K396 E519 V521	K396-E523 WeakPolarHBondContact CE-OE1 3.36Å; K396-E523 WeakPolarHBondContact CE-OE2 3.48Å; K396-E523 IonicContact NZ-OE1 3.4Å; K396-E523 PolarHBondContact NZ-OE1 3.17Å; K396-E523 IonicContact NZ-OE2 3.94Å; K396-E523 PolarHBondContact NZ-OE2 3.41Å; K396-E523 VanDerWaalsContact NZ-OE2 3.1Å; E519-E523 WeakPolarHBondContact O-CG 3.35Å; V521-E523 PolarHBondContact O-N 2.93Å
524	E	40.9	Very low	46.6	Very low	113 Å²	113	80.9 Å²	80.9	53%	0.528	45%	0.446	S	S	.	.	H	α-helix	trans	-92.3	-26.2	177.1	-64.1	-176	147.5	0	0	113.2	R401 V521 D522	R401-E524 PolarHBondContact NH1-O 3.25Å; R401-E524 PolarHBondContact NH2-O 2.86Å; V521-E524 WeakPolarHBondContact O-CA 3.39Å; V521-E524 VanDerWaalsContact O-CB 3.26Å; V521-E524 WeakPolarHBondContact O-CB 3.41Å; V521-E524 PolarHBondContact O-N 3.4Å; D522-E524 PolarHBondContact O-N 3.28Å
525	S	40.8	Very low	44.5	Very low	22 Å²	22	78.7 Å²	78.7	15%	0.154	45%	0.451	C	S	.	.	H	α-helix	trans	-97.5	-21.5	-172.8	49.1	0	0	0	0	115.2	D522 I527 S528	D522-S525 PolarHBondContact O-OG 3.25Å; S525-I527 PolarHBondContact O-N 3.02Å; S525-S528 PolarHBondContact O-N 3.45Å; S525-S528 VanDerWaalsContact O-N 3.12Å; S525-S528 PolarHBondContact O-OG 3.45Å; S525-S528 VanDerWaalsContact O-OG 3.06Å
526	D	41.9	Very low	42.6	Very low	124 Å²	124	86.6 Å²	86.6	66%	0.663	48%	0.481	S	S	*	.	T	Hydrogen-bonded Turn	trans	-64.1	5.5	-174.1	-79	-14.5	0	0	0	116.8
527	I	41.4	Very low	41	Very low	86 Å²	86	90.9 Å²	90.9	44%	0.441	51%	0.511	S	S	.	.	T	Hydrogen-bonded Turn	trans	-130.7	-4.5	175	-59.2	174.8	0	0	0	112.4	S525 D529	S525-I527 PolarHBondContact O-N 3.02Å; I527-D529 PolarHBondContact O-N 2.94Å
528	S	36.5	Very low	39.4	Very low	65 Å²	65	100.1 Å²	100.1	46%	0.455	57%	0.567	S	S	.	*	T	Hydrogen-bonded Turn	trans	-70.8	-11.9	175.5	52.5	0	0	0	0	113.7	S525	S525-S528 PolarHBondContact O-N 3.45Å; S525-S528 VanDerWaalsContact O-N 3.12Å; S525-S528 PolarHBondContact O-OG 3.45Å; S525-S528 VanDerWaalsContact O-OG 3.06Å
529	D	38.5	Very low	38.5	Very low	101 Å²	101	105.1 Å²	105.1	54%	0.54	60%	0.595	S	S	.	*	T	Hydrogen-bonded Turn	trans	-95.8	-8.3	-173.9	-71	-0.1	0	0	0	114.2	K278 I527	K278-D529 IonicContact NZ-OD2 3.88Å; K278-D529 PolarHBondContact NZ-OD2 3.21Å; I527-D529 PolarHBondContact O-N 2.94Å
530	D	36.6	Very low	37.6	Very low	141 Å²	141	105.4 Å²	105.4	75%	0.754	60%	0.602	S	S	*	*	S	Bend	trans	-93.9	-8.1	-179.8	-79	-24.9	0	0	0	114.2
531	D	33	Very low	36.8	Very low	126 Å²	126	108.4 Å²	108.4	67%	0.674	61%	0.607	S	S	*	*	S	Bend	trans	-125.8	30.2	-176.9	-72.4	-39.7	0	0	0	113.8	P533	D531-P533 VanDerWaalsContact O-CD 3.22Å; D531-P533 WeakPolarHBondContact O-CD 3.45Å
532	E	26.9	Very low	36.1	Very low	172 Å²	172	112.9 Å²	112.9	80%	0.804	63%	0.631	S	S	*	*			trans	-91.8	103.4	164.1	-133.8	-179.8	-165.3	0	0	108.2	S534	E532-S534 PolarHBondContact O-N 3.45Å
533	P	31.8	Very low	35.8	Very low	112 Å²	112	117.6 Å²	117.6	73%	0.727	66%	0.657	S	S	*	*			trans	-62.1	117.7	171.4	23.9	-29.6	0	0	0	107.5	D531 A535	D531-P533 VanDerWaalsContact O-CD 3.22Å; D531-P533 WeakPolarHBondContact O-CD 3.45Å; P533-A535 PolarHBondContact O-N 2.92Å
534	S	31.9	Very low	35.3	Very low	116 Å²	116	121.4 Å²	121.4	81%	0.811	68%	0.682	S	S	*	*			trans	-58.3	82.3	172.3	56.3	0	0	0	0	110.3	E532 Y536	E532-S534 PolarHBondContact O-N 3.45Å; S534-Y536 PolarHBondContact O-N 3.43Å
535	A	33.2	Very low	34.9	Very low	82 Å²	82	122 Å²	122	68%	0.678	69%	0.693	S	S	*	*			trans	-89.2	63.7	170.9	0	0	0	0	0	109.5	P533	P533-A535 PolarHBondContact O-N 2.92Å
536	Y	34.6	Very low	34.4	Very low	232 Å²	232	129.7 Å²	129.7	91%	0.91	74%	0.735	S	S	*	*			trans	-144.7	82.9	159.7	-75.7	-68.9	0	0	0	110.1	S534	S534-Y536 PolarHBondContact O-N 3.43Å
537	S	28.4	Very low	33.8	Very low	112 Å²	112	130.2 Å²	130.2	78%	0.783	74%	0.741	S	S	*	*			trans	-172.1	105.8	152	56.7	0	0	0	0	104.2
538	V	32.6	Very low	33.1	Very low	217 Å²	217	134.2 Å²	134.2	100%	1.315	77%	0.768	S	S	*	*				-148.9	0	61	169.4	0	0	0	0	110

Retrieved 538 of 538 residues in 190.3 ms (Link to these results)

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