A0A061IQ70_CRIGR Loading...

Vang-like protein

AlphaFold DB , UniProt , Accession A0A061IQ70, Species CRIGR (Cricetulus griseus, Chinese hamster), Gene Vangl1, Length 526 aa.

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	38.7	Very low	34.3	Very low	236 Å²	236	150.2 Å²	150.2	100%	1.163	82%	0.82	S	S	*	*				0	97	0	-97.5	-170	169.8	0	0	105.7
2	D	36.9	Very low	33.8	Very low	147 Å²	147	152.2 Å²	152.2	79%	0.786	81%	0.809	S	S	*	*			trans	-102	148.2	-160.5	-48.3	-93.6	0	0	0	107.9
3	T	41.5	Very low	33.3	Very low	151 Å²	151	156.8 Å²	156.8	93%	0.926	81%	0.811	S	S	*	*			trans	-142.1	129.9	153.5	31.7	0	0	0	0	108.6
4	E	38.3	Very low	33	Very low	173 Å²	173	152.9 Å²	152.9	81%	0.808	80%	0.803	S	S	*	*			trans	-95.4	156.2	-163.5	-61.2	169	102.1	0	0	113.4
5	S	37.7	Very low	32.5	Very low	108 Å²	108	148.5 Å²	148.5	76%	0.755	79%	0.79	S	S	*	*			trans	69.1	144.9	144.2	79.3	0	0	0	0	118
6	T	32.5	Very low	32.3	Very low	133 Å²	133	150.6 Å²	150.6	82%	0.816	79%	0.794	S	S	*	*				-157.9	143	78.5	-60.7	0	0	0	0	111.5
7	Y	33.3	Very low	32.1	Very low	217 Å²	217	147 Å²	147	85%	0.851	78%	0.784	S	S	*	*			trans	-80	139.9	175.8	173	-85.1	0	0	0	111.8
8	S	33.3	Very low	32	Very low	118 Å²	118	149.8 Å²	149.8	83%	0.825	79%	0.788	S	S	*	*			trans	-149.1	130	159.5	57.4	0	0	0	0	113.4
9	G	28.2	Very low	31.9	Very low	50 Å²	50	151.7 Å²	151.7	52%	0.515	79%	0.789	S	S	.	*			trans	-126.7	-176.2	162.1	0	0	0	0	0	109.8
10	Y	29.2	Very low	31.9	Very low	214 Å²	214	150.3 Å²	150.3	84%	0.839	79%	0.793	S	S	*	*			trans	68.1	147.8	-167.4	-83.9	-102.7	0	0	0	114.1	Y12	Y10-Y12 HydrophobicContact CD1-CD2 4.25Å; Y10-Y12 AromaticContact CE1-CD2 3.99Å; Y10-Y12 HydrophobicContact CE1-CD2 3.99Å; Y10-Y12 HydrophobicContact CE1-CE2 4.34Å
11	S	28.1	Very low	31.9	Very low	105 Å²	105	150.1 Å²	150.1	73%	0.734	79%	0.787	S	S	*	*			cis	-146.7	146.4	11.1	40.7	0	0	0	0	109.5
12	Y	27.5	Very low	31.5	Very low	174 Å²	174	151 Å²	151	68%	0.682	78%	0.777	S	S	*	*				77.7	125.2	68.3	-108.7	-63.2	0	0	0	117.2	Y10	Y10-Y12 HydrophobicContact CD1-CD2 4.25Å; Y10-Y12 AromaticContact CE1-CD2 3.99Å; Y10-Y12 HydrophobicContact CE1-CD2 3.99Å; Y10-Y12 HydrophobicContact CE1-CE2 4.34Å
13	Y	28.2	Very low	31.3	Very low	213 Å²	213	151.3 Å²	151.3	84%	0.835	77%	0.774	S	S	*	*			trans	64.8	149.9	171.7	-77	-79.6	0	0	0	116.9
14	S	28.3	Very low	30.7	Very low	101 Å²	101	148 Å²	148	71%	0.706	77%	0.769	S	S	*	*			cis	-160.4	177.4	-3.4	100.2	0	0	0	0	107.9
15	S	26.6	Very low	30.4	Very low	87 Å²	87	147 Å²	147	61%	0.608	77%	0.765	S	S	*	*			cis	-176.3	172.9	-22.6	55	0	0	0	0	109
16	H	28.9	Very low	30	Very low	183 Å²	183	152.4 Å²	152.4	85%	0.847	77%	0.769	S	S	*	*			trans	64.1	152.9	173.2	-77.2	-85.5	0	0	0	117.4
17	S	28.9	Very low	29.9	Very low	89 Å²	89	152.5 Å²	152.5	62%	0.622	77%	0.769	S	S	*	*			cis	-158.3	167.6	-8.8	52.7	0	0	0	0	107
18	K	29.8	Very low	30.1	Very low	198 Å²	198	153.7 Å²	153.7	86%	0.861	77%	0.772	S	S	*	*			cis	-156.6	141.9	45.5	-67.7	176	176.7	171.8	0	111.9
19	K	30.5	Very low	30	Very low	186 Å²	186	155.7 Å²	155.7	81%	0.809	77%	0.769	S	S	*	*	P	Polyproline II helix	trans	-81.3	147.8	155.3	-80.1	177	171	177.7	0	109.3
20	S	32.6	Very low	30.5	Very low	123 Å²	123	164.8 Å²	164.8	86%	0.86	79%	0.787	S	S	*	*	P	Polyproline II helix	trans	-100	116.7	156.6	47.6	0	0	0	0	109.7
21	H	30.9	Very low	30.7	Very low	146 Å²	146	161.9 Å²	161.9	68%	0.676	78%	0.781	S	S	*	*	P	Polyproline II helix	trans	-87.9	138.4	167.1	-108.3	-97.7	0	0	0	109
22	R	31.1	Very low	31	Very low	255 Å²	255	166.9 Å²	166.9	96%	0.962	79%	0.79	S	S	*	*			trans	-126	126	145.5	-103.6	-175.4	172.6	178.2	-1.9	107.8
23	Q	31.5	Very low	31.1	Very low	154 Å²	154	164 Å²	164	72%	0.72	80%	0.795	S	S	*	*			trans	-119.5	134.1	-174.9	-174.4	174.9	-0.5	0	0	107.6
24	G	29.5	Very low	31.5	Very low	80 Å²	80	160 Å²	160	83%	0.825	80%	0.795	S	S	*	*			trans	-150.9	100.3	176	0	0	0	0	0	108
25	E	31.4	Very low	31.6	Very low	152 Å²	152	165.6 Å²	165.6	71%	0.71	80%	0.801	S	S	*	*			trans	-86.9	172	179.4	-75.2	-169	127.1	0	0	112.5
26	R	30.6	Very low	31.8	Very low	222 Å²	222	167.2 Å²	167.2	84%	0.838	81%	0.812	S	S	*	*			trans	82.6	135.4	168.2	-50	-179.8	-177.7	-177.1	-0.5	113.3
27	T	29.3	Very low	32	Very low	135 Å²	135	166.6 Å²	166.6	83%	0.828	81%	0.807	S	S	*	*			cis	-152.5	165.6	4.2	-10.2	0	0	0	0	111
28	R	38.5	Very low	32.1	Very low	242 Å²	242	170.5 Å²	170.5	91%	0.913	82%	0.821	S	S	*	*			trans	-57.1	138.2	167.8	-73.3	170.4	164	155.8	-6	110.8
29	E	29.9	Very low	32.2	Very low	160 Å²	160	163.9 Å²	163.9	75%	0.748	81%	0.809	S	S	*	*			trans	-152.4	139.8	137.8	-127.9	172.4	-137.6	0	0	113.2	H31	E29-H31 IonicContact OE2-CD2 3.6Å; E29-H31 IonicContact OE2-CE1 3.71Å; E29-H31 IonicContact OE2-NE2 3.33Å; E29-H31 PolarHBondContact OE2-NE2 3.39Å
30	R	39.4	Very low	32.2	Very low	241 Å²	241	167.5 Å²	167.5	91%	0.909	82%	0.818	S	S	*	*			trans	-86.6	121.1	169.7	-84.2	174	162.2	175.9	-4.6	107.5
31	H	34.3	Very low	32.1	Very low	154 Å²	154	165.4 Å²	165.4	71%	0.713	82%	0.816	S	S	*	*			trans	-119.5	112.8	160.9	-79.7	-63.9	0	0	0	112	E29	E29-H31 IonicContact OE2-CD2 3.6Å; E29-H31 IonicContact OE2-CE1 3.71Å; E29-H31 IonicContact OE2-NE2 3.33Å; E29-H31 PolarHBondContact OE2-NE2 3.39Å
32	K	33	Very low	32.2	Very low	210 Å²	210	163.8 Å²	163.8	91%	0.913	82%	0.821	S	S	*	*			trans	-70	139.9	158.8	-71	170.3	170.7	174.8	0	107.6
33	S	30.5	Very low	32.3	Very low	113 Å²	113	160.8 Å²	160.8	79%	0.79	82%	0.818	S	S	*	*			trans	-110.6	152.4	156	57.1	0	0	0	0	109.8
34	P	36	Very low	32.4	Very low	128 Å²	128	162.4 Å²	162.4	83%	0.831	82%	0.823	S	S	*	*			trans	-94.2	156.5	-149.7	35.1	-36.1	0	0	0	115.2
35	R	30.1	Very low	32.5	Very low	219 Å²	219	164.3 Å²	164.3	83%	0.826	82%	0.823	S	S	*	*			trans	-75.7	113.6	172.6	-174.3	-173.9	-162	171.4	5.5	109.5
36	S	31.6	Very low	32.4	Very low	122 Å²	122	162.1 Å²	162.1	85%	0.853	82%	0.82	S	S	*	*			trans	-73.3	137	157.9	52.7	0	0	0	0	108.8
37	K	31.8	Very low	32.5	Very low	169 Å²	169	158.3 Å²	158.3	74%	0.735	82%	0.821	S	S	*	*			trans	-147.3	88.5	-177	-172.4	-160.6	176.8	-169.1	0	110.5
38	D	32.8	Very low	32.5	Very low	171 Å²	171	158.9 Å²	158.9	91%	0.914	82%	0.818	S	S	*	*			trans	-127	140.2	152.4	-68.1	-56.7	0	0	0	106.2
39	G	30.6	Very low	32.2	Very low	60 Å²	60	156.1 Å²	156.1	62%	0.619	82%	0.815	S	S	*	*			cis	156.3	122.4	-1.6	0	0	0	0	0	108.8
40	R	31.6	Very low	32.1	Very low	261 Å²	261	152.9 Å²	152.9	99%	0.985	82%	0.816	S	S	*	*			trans	73	137.3	-172	-46.2	169.4	-178	-135.9	-1.9	113.8
41	G	30.6	Very low	31.8	Very low	80 Å²	80	147.2 Å²	147.2	83%	0.825	81%	0.81	S	S	*	*			cis	139.6	104.2	-9.2	0	0	0	0	0	113
42	S	31.8	Very low	32	Very low	112 Å²	112	147 Å²	147	78%	0.783	82%	0.82	S	S	*	*			trans	-174	118.8	145.6	-173	0	0	0	0	109.2
43	E	34.3	Very low	31.7	Very low	191 Å²	191	140.4 Å²	140.4	89%	0.893	81%	0.812	S	S	*	*			trans	-76.5	136.5	163	-63.5	169	153.4	0	0	108.7
44	K	33.3	Very low	32	Very low	189 Å²	189	144.3 Å²	144.3	82%	0.822	82%	0.817	S	S	*	*			trans	-164.7	89.4	155.2	-111.3	166.5	-171.4	-177.7	0	110	V46	K44-V46 PolarHBondContact O-N 3.16Å
45	S	31.8	Very low	31.8	Very low	119 Å²	119	143.8 Å²	143.8	83%	0.832	81%	0.814	S	S	*	*			trans	-68.1	121.1	162.2	50.5	0	0	0	0	109.2
46	V	27.8	Very low	31.7	Very low	107 Å²	107	140.8 Å²	140.8	65%	0.648	81%	0.813	S	S	*	*			trans	-127.9	106.3	167.7	-173.2	0	0	0	0	108.3	K44 I48	K44-V46 PolarHBondContact O-N 3.16Å; V46-I48 HydrophobicContact CG1-CD1 4.29Å; V46-I48 HydrophobicContact CG1-CG1 3.75Å; V46-I48 PolarHBondContact O-N 3.39Å
47	T	33.5	Very low	31.9	Very low	141 Å²	141	142.7 Å²	142.7	87%	0.865	81%	0.813	S	S	*	*			trans	-75.3	110.3	168.1	-50.8	0	0	0	0	107.7
48	I	29.8	Very low	31.6	Very low	148 Å²	148	139.4 Å²	139.4	76%	0.759	82%	0.818	S	S	*	*	P	Polyproline II helix	trans	-101.3	116.2	172.7	-57.6	-175.9	0	0	0	108.5	V46	V46-I48 HydrophobicContact CG1-CD1 4.29Å; V46-I48 HydrophobicContact CG1-CG1 3.75Å; V46-I48 PolarHBondContact O-N 3.39Å
49	Q	30.7	Very low	31.4	Very low	184 Å²	184	138.6 Å²	138.6	86%	0.86	81%	0.813	S	S	*	*	P	Polyproline II helix	trans	-79	118.2	175.3	-160	166.3	7.1	0	0	108
50	A	29.2	Very low	31.2	Very low	91 Å²	91	143.4 Å²	143.4	75%	0.752	83%	0.825	S	S	*	*	P	Polyproline II helix	trans	-77.5	132.3	179.9	0	0	0	0	0	110.6
51	P	31.8	Very low	31.1	Very low	123 Å²	123	136.6 Å²	136.6	80%	0.799	82%	0.817	S	S	*	*	P	Polyproline II helix	trans	-76.7	154.9	173.5	32.6	-34.5	0	0	0	111.5
52	T	38.6	Very low	30.9	Very low	150 Å²	150	136.7 Å²	136.7	92%	0.92	81%	0.81	S	S	*	*	P	Polyproline II helix	trans	-62.5	130.4	168.7	41.4	0	0	0	0	111.6
53	G	28.4	Very low	30.8	Very low	71 Å²	71	137.5 Å²	137.5	73%	0.732	81%	0.813	S	S	*	*			trans	-155.4	118.7	169.1	0	0	0	0	0	110.7
54	E	34.9	Very low	30.6	Very low	194 Å²	194	135.3 Å²	135.3	91%	0.907	81%	0.813	S	S	*	*			trans	-66.8	153.5	165.3	-61.7	-178.7	137.6	0	0	110.2
55	P	32.2	Very low	30.4	Very low	117 Å²	117	129.4 Å²	129.4	76%	0.76	81%	0.805	S	S	*	*				-140.2	121.4	127.8	31.9	-16.8	0	0	0	114.1
56	L	27.9	Very low	30.4	Very low	156 Å²	156	128.1 Å²	128.1	82%	0.817	80%	0.802	S	S	*	*				27.5	115.7	127.6	-63.7	170.2	0	0	0	119.4
57	L	35.6	Very low	30.7	Very low	163 Å²	163	131.2 Å²	131.2	85%	0.853	81%	0.809	S	S	*	*			trans	34.3	106.2	136	-64.7	172.8	0	0	0	118.8
58	A	25.7	Very low	30.5	Very low	100 Å²	100	133.5 Å²	133.5	83%	0.826	81%	0.81	S	S	*	*			trans	-133.4	118.6	146.2	0	0	0	0	0	109
59	N	29.1	Very low	30.9	Very low	154 Å²	154	131.7 Å²	131.7	82%	0.824	81%	0.806	S	S	*	*			trans	-70.4	131.1	166	-90	-9.3	0	0	0	108.7
60	D	26.5	Very low	31.4	Very low	160 Å²	160	129.7 Å²	129.7	86%	0.856	80%	0.796	S	S	*	*				-162.5	151	122.9	-103.4	-24.5	0	0	0	111.7	A62	D60-A62 PolarHBondContact O-N 2.98Å
61	S	30.3	Very low	32.2	Very low	119 Å²	119	131.4 Å²	131.4	83%	0.832	79%	0.793	S	S	*	*			trans	-59	117.3	-164.1	54.5	0	0	0	0	115.5
62	A	25.7	Very low	33.3	Very low	81 Å²	81	127.4 Å²	127.4	67%	0.669	77%	0.765	S	S	*	*			trans	-104.4	140	151.9	0	0	0	0	0	108.7	D60 T64	D60-A62 PolarHBondContact O-N 2.98Å; A62-T64 PolarHBondContact O-N 3.49Å
63	P	30.4	Very low	34.2	Very low	130 Å²	130	122.6 Å²	122.6	84%	0.844	73%	0.734	S	S	*	*			trans	-69.5	124.7	-179.2	28	-33.2	0	0	0	110.3	G65	P63-G65 PolarHBondContact O-N 3.39Å
64	T	29.4	Very low	35.9	Very low	145 Å²	145	126.9 Å²	126.9	89%	0.89	73%	0.728	S	S	*	*			trans	-67.8	78.9	175.8	-41.1	0	0	0	0	110.4	A62 A66	A62-T64 PolarHBondContact O-N 3.49Å; T64-A66 PolarHBondContact O-N 3.46Å
65	G	29.8	Very low	36.9	Very low	65 Å²	65	118.8 Å²	118.8	67%	0.67	70%	0.697	S	S	*	*			trans	-69.8	105	162.1	0	0	0	0	0	108.1	P63 E67	P63-G65 PolarHBondContact O-N 3.39Å; G65-E67 PolarHBondContact O-N 2.99Å
66	A	30.2	Very low	37.7	Very low	91 Å²	91	117.8 Å²	117.8	75%	0.752	68%	0.682	S	S	*	*			trans	-61.2	104.9	170.7	0	0	0	0	0	108.7	T64 E68	T64-A66 PolarHBondContact O-N 3.46Å; A66-E68 PolarHBondContact O-N 2.98Å; A66-E68 VanDerWaalsContact O-N 3.14Å
67	E	35.5	Very low	38.6	Very low	172 Å²	172	117 Å²	117	80%	0.804	68%	0.684	S	S	*	*			trans	-71.5	101.1	161.6	-70.4	-168.1	144.5	0	0	106.9	G65 V69	G65-E67 PolarHBondContact O-N 2.99Å; E67-V69 HydrophobicContact CB-CG2 3.85Å; E67-V69 PolarHBondContact O-N 3.1Å
68	E	29.8	Very low	38.8	Very low	189 Å²	189	115.2 Å²	115.2	88%	0.883	68%	0.679	S	S	*	*			trans	-63.6	84.4	158.4	-71.5	-175.5	147.6	0	0	107.8	A66 Q70	A66-E68 PolarHBondContact O-N 2.98Å; A66-E68 VanDerWaalsContact O-N 3.14Å; E68-Q70 PolarHBondContact O-N 3.41Å
69	V	38.1	Very low	39.4	Very low	111 Å²	111	117 Å²	117	67%	0.673	68%	0.68	S	S	*	*			trans	-74.7	81.5	174.6	-176.2	0	0	0	0	108	E67 D71	E67-V69 HydrophobicContact CB-CG2 3.85Å; E67-V69 PolarHBondContact O-N 3.1Å; V69-D71 PolarHBondContact O-N 2.89Å; V69-D71 VanDerWaalsContact O-N 3.13Å
70	Q	40.3	Very low	39.7	Very low	141 Å²	141	114.2 Å²	114.2	66%	0.659	68%	0.679	S	S	*	*			trans	-66.1	108.2	166.7	-171.6	170	-17.1	0	0	108.4	E68 D72	E68-Q70 PolarHBondContact O-N 3.41Å; Q70-D72 PolarHBondContact NE2-OD2 3.45Å; Q70-D72 PolarHBondContact O-N 3.05Å
71	D	45.7	Very low	40.2	Very low	127 Å²	127	114.6 Å²	114.6	68%	0.679	68%	0.679	S	S	*	*			trans	-78.5	64	-172.2	-166.3	17.8	0	0	0	112.6	V69 N73	V69-D71 PolarHBondContact O-N 2.89Å; V69-D71 VanDerWaalsContact O-N 3.13Å; D71-N73 PolarHBondContact O-N 3.26Å
72	D	54.3	Low	40.4	Very low	40 Å²	40	115.5 Å²	115.5	21%	0.214	68%	0.68	C	S	.	*			trans	-77.3	60.3	176.1	-79.9	-48.5	0	0	0	111.4	Q70 W74 Q408	Q70-D72 PolarHBondContact NE2-OD2 3.45Å; Q70-D72 PolarHBondContact O-N 3.05Å; D72-W74 VanDerWaalsContact C-CD1 3.49Å; D72-W74 VanDerWaalsContact C-N 3.35Å; D72-W74 PolarHBondContact O-N 3.2Å; D72-W74 PolarHBondContact OD1-NE1 3.47Å; D72-Q408 PolarHBondContact O-NE2 3.08Å
73	N	59.2	Low	41.3	Very low	49 Å²	49	115 Å²	115	26%	0.262	68%	0.683	S	S	.	*			trans	-93.2	36.6	-177	-148.6	10.4	0	0	0	115.6	D71 G75 E76 Q408 R412	D71-N73 PolarHBondContact O-N 3.26Å; N73-G75 PolarHBondContact O-N 2.95Å; N73-E76 PolarHBondContact ND2-OE2 2.85Å; N73-E76 PolarHBondContact O-N 2.89Å; N73-E76 WeakPolarHBondContact OD1-CB 3.37Å; N73-E76 WeakPolarHBondContact OD1-CG 3.48Å; N73-E76 PolarHBondContact OD1-OE2 2.83Å; N73-Q408 PolarHBondContact OD1-NE2 2.65Å; N73-R412 PolarHBondContact OD1-NH2 3.23Å
74	W	63.3	Low	41.2	Very low	160 Å²	160	115.2 Å²	115.2	61%	0.606	68%	0.682	S	S	*	*	T	Hydrogen-bonded Turn	trans	-60.1	11.5	-178.5	-48.4	93.6	0	0	0	117	D72 M422	D72-W74 VanDerWaalsContact C-CD1 3.49Å; D72-W74 VanDerWaalsContact C-N 3.35Å; D72-W74 PolarHBondContact O-N 3.2Å; D72-W74 PolarHBondContact OD1-NE1 3.47Å; W74-M422 HydrophobicContact CB-SD 3.84Å; W74-M422 HydrophobicContact CD2-CB 4.17Å; W74-M422 HydrophobicContact CD2-SD 3.54Å; W74-M422 VanDerWaalsContact CD2-SD 3.54Å; W74-M422 HydrophobicContact CE3-SD 3.38Å; W74-M422 HydrophobicContact CG-CB 4.18Å; W74-M422 HydrophobicContact CG-SD 3.75Å; W74-M422 HydrophobicContact CZ3-SD 4.14Å
75	G	56.8	Low	41.9	Very low	25 Å²	25	113.9 Å²	113.9	26%	0.258	68%	0.678	S	S	.	*	T	Hydrogen-bonded Turn	trans	-140.8	8.6	-174.9	0	0	0	0	0	115.4	N73	N73-G75 PolarHBondContact O-N 2.95Å
76	E	47.9	Very low	42	Very low	96 Å²	96	119.1 Å²	119.1	45%	0.449	69%	0.685	S	S	.	*	S	Bend	trans	-129.4	112.2	176.5	-63.9	173.5	-176.7	0	0	108.7	N73 R412	N73-E76 PolarHBondContact ND2-OE2 2.85Å; N73-E76 PolarHBondContact O-N 2.89Å; N73-E76 WeakPolarHBondContact OD1-CB 3.37Å; N73-E76 WeakPolarHBondContact OD1-CG 3.48Å; N73-E76 PolarHBondContact OD1-OE2 2.83Å; E76-R412 IonicContact OE1-CZ 3.76Å; E76-R412 IonicContact OE1-NH1 2.69Å; E76-R412 PolarHBondContact OE1-NH1 3.43Å; E76-R412 IonicContact OE2-NH1 3.22Å
77	T	47.1	Very low	42.2	Very low	139 Å²	139	124.4 Å²	124.4	85%	0.853	69%	0.694	S	S	*	*			trans	-74.6	134.1	178.2	37.1	0	0	0	0	111.4
78	T	40.4	Very low	42.2	Very low	125 Å²	125	121.4 Å²	121.4	77%	0.767	69%	0.692	S	S	*	*			trans	83.3	94.5	162.3	-43.3	0	0	0	0	117.4
79	T	38.8	Very low	42.8	Very low	137 Å²	137	118.7 Å²	118.7	84%	0.84	68%	0.682	S	S	*	*				-167.7	141.1	111.5	28.4	0	0	0	0	112.7
80	A	34.8	Very low	42.9	Very low	96 Å²	96	115.5 Å²	115.5	79%	0.793	67%	0.665	S	S	*	*			trans	29.1	117	159.1	0	0	0	0	0	121.1
81	I	36.6	Very low	43	Very low	169 Å²	169	117 Å²	117	87%	0.867	67%	0.672	S	S	*	*			trans	-81	125.6	162.4	-62.7	164.9	0	0	0	109.5
82	T	33.5	Very low	43.3	Very low	137 Å²	137	117.7 Å²	117.7	84%	0.84	67%	0.671	S	S	*	*			trans	-133.7	110.5	155	37.3	0	0	0	0	108.5
83	G	44.9	Very low	43.1	Very low	71 Å²	71	118.9 Å²	118.9	73%	0.732	68%	0.678	S	S	*	*			trans	-87.8	134.8	175.7	0	0	0	0	0	111.7
84	T	29.6	Very low	42.9	Very low	135 Å²	135	121.3 Å²	121.3	83%	0.828	69%	0.69	S	S	*	*			trans	-139.3	134.4	156.4	44.4	0	0	0	0	107.9
85	S	44.2	Very low	42.3	Very low	117 Å²	117	116.7 Å²	116.7	82%	0.818	69%	0.685	S	S	*	*			trans	-106.7	118.5	-176.8	54.5	0	0	0	0	110.6
86	E	31.1	Very low	42.2	Very low	175 Å²	175	122.9 Å²	122.9	82%	0.818	70%	0.701	S	S	*	*			trans	-136.3	102.3	172	-66.7	-167.2	-173.9	0	0	111.2
87	H	33.5	Very low	42.4	Very low	201 Å²	201	122.2 Å²	122.2	93%	0.931	70%	0.699	S	S	*	*			trans	-82.8	112.5	158.1	-94.2	-40.8	0	0	0	108.1
88	S	36.1	Very low	42.6	Very low	109 Å²	109	118.4 Å²	118.4	76%	0.762	68%	0.678	S	S	*	*			trans	-121.7	102.9	166.5	52.9	0	0	0	0	110
89	I	42.6	Very low	43.1	Very low	132 Å²	132	119.3 Å²	119.3	68%	0.677	67%	0.672	S	S	*	*			trans	-83.5	128.1	167.1	-64.9	175	0	0	0	107	I94	I89-I94 HydrophobicContact CG2-CG1 4.27Å
90	S	40.5	Very low	43.6	Very low	44 Å²	44	116.1 Å²	116.1	31%	0.308	65%	0.65	S	S	.	*			trans	-70.6	146.6	-175.7	87.6	0	0	0	0	111.8	E92 D93 I94	S90-E92 PolarHBondContact O-N 3.28Å; S90-E92 PolarHBondContact OG-N 3.07Å; S90-D93 PolarHBondContact O-N 3.4Å; S90-D93 PolarHBondContact OG-N 3.45Å; S90-D93 PolarHBondContact OG-OD2 3.39Å; S90-I94 PolarHBondContact O-N 3.32Å
91	Q	42.5	Very low	44.2	Very low	173 Å²	173	117.1 Å²	117.1	81%	0.808	64%	0.639	S	S	*	*	H	α-helix	trans	-64	-21.5	176.5	-167.8	174.4	0.7	0	0	112.2	A95	Q91-A95 PolarHBondContact O-N 2.92Å
92	E	51.5	Low	44.6	Very low	141 Å²	141	116.1 Å²	116.1	66%	0.659	63%	0.631	S	S	*	*	H	α-helix	trans	-75.7	-32.2	178.8	-67.9	160.3	-172	0	0	112.1	S90 R96	S90-E92 PolarHBondContact O-N 3.28Å; S90-E92 PolarHBondContact OG-N 3.07Å; E92-R96 WeakPolarHBondContact O-CG 3.33Å; E92-R96 PolarHBondContact O-N 3.29Å
93	D	49.6	Very low	45.5	Very low	66 Å²	66	114.9 Å²	114.9	35%	0.353	62%	0.619	S	S	.	*	H	α-helix	trans	-72.2	-39.5	173.7	-62.4	-48.5	0	0	0	111.2	S90 A95 R96 I97	S90-D93 PolarHBondContact O-N 3.4Å; S90-D93 PolarHBondContact OG-N 3.45Å; S90-D93 PolarHBondContact OG-OD2 3.39Å; D93-A95 VanDerWaalsContact C-N 3.31Å; D93-A95 PolarHBondContact O-N 3.45Å; D93-R96 PolarHBondContact O-N 3.27Å; D93-R96 IonicContact OD1-NH1 3.36Å; D93-R96 PolarHBondContact OD1-NH1 3.45Å; D93-I97 WeakPolarHBondContact O-CD1 3.44Å; D93-I97 VanDerWaalsContact O-CG1 3.23Å; D93-I97 WeakPolarHBondContact O-CG1 3.27Å; D93-I97 PolarHBondContact O-N 3.3Å
94	I	54.7	Low	45.9	Very low	100 Å²	100	114.3 Å²	114.3	51%	0.513	60%	0.604	S	S	.	*	H	α-helix	trans	-61	-41.1	174.4	-59.7	173.8	0	0	0	110.8	I89 S90 R96 I97 S98	I89-I94 HydrophobicContact CG2-CG1 4.27Å; S90-I94 PolarHBondContact O-N 3.32Å; I94-R96 PolarHBondContact O-N 3.47Å; I94-I97 PolarHBondContact O-N 2.89Å; I94-S98 PolarHBondContact O-N 3.35Å
95	A	51.8	Low	46.8	Very low	63 Å²	63	113.1 Å²	113.1	52%	0.521	60%	0.596	S	S	.	*	H	α-helix	trans	-66.8	-33.2	177.4	0	0	0	0	0	113.3	Q91 D93 K99	Q91-A95 PolarHBondContact O-N 2.92Å; D93-A95 VanDerWaalsContact C-N 3.31Å; D93-A95 PolarHBondContact O-N 3.45Å; A95-K99 PolarHBondContact O-N 2.93Å
96	R	54.3	Low	46.7	Very low	155 Å²	155	110 Å²	110	59%	0.585	58%	0.583	S	S	*	*	H	α-helix	trans	-69.2	-49.3	171.7	-72	175.5	-177.5	138.4	2.8	111.3	E92 D93 I94 S98 K99 D100	E92-R96 WeakPolarHBondContact O-CG 3.33Å; E92-R96 PolarHBondContact O-N 3.29Å; D93-R96 PolarHBondContact O-N 3.27Å; D93-R96 IonicContact OD1-NH1 3.36Å; D93-R96 PolarHBondContact OD1-NH1 3.45Å; I94-R96 PolarHBondContact O-N 3.47Å; R96-S98 VanDerWaalsContact C-N 3.3Å; R96-S98 PolarHBondContact O-N 3.01Å; R96-K99 PolarHBondContact O-N 3.33Å; R96-D100 PolarHBondContact O-N 2.94Å
97	I	53.1	Low	47.6	Very low	81 Å²	81	107 Å²	107	42%	0.415	57%	0.572	S	S	.	*	H	α-helix	trans	-56	-43.8	178.9	-68.5	162.7	0	0	0	111.3	D93 I94 K99 M101 W460	D93-I97 WeakPolarHBondContact O-CD1 3.44Å; D93-I97 VanDerWaalsContact O-CG1 3.23Å; D93-I97 WeakPolarHBondContact O-CG1 3.27Å; D93-I97 PolarHBondContact O-N 3.3Å; I94-I97 PolarHBondContact O-N 2.89Å; I97-K99 VanDerWaalsContact C-N 3.29Å; I97-K99 PolarHBondContact O-N 3.42Å; I97-M101 WeakPolarHBondContact O-CB 3.38Å; I97-M101 PolarHBondContact O-N 3.05Å; I97-M101 VanDerWaalsContact O-N 3.09Å; I97-W460 HydrophobicContact CG1-CH2 4.33Å
98	S	49.9	Very low	48.5	Very low	59 Å²	59	100.4 Å²	100.4	41%	0.413	54%	0.543	S	S	.	.	H	α-helix	trans	-62.5	-35.9	177.3	-167.9	0	0	0	0	112.7	I94 R96 E102	I94-S98 PolarHBondContact O-N 3.35Å; R96-S98 VanDerWaalsContact C-N 3.3Å; R96-S98 PolarHBondContact O-N 3.01Å; S98-E102 PolarHBondContact O-N 3.35Å
99	K	50.8	Low	49.3	Very low	145 Å²	145	100.1 Å²	100.1	63%	0.63	54%	0.54	S	S	*	.	H	α-helix	trans	-76.4	-40	-177.6	-174.3	163.8	-176.8	156.7	0	112.5	A95 R96 I97 M101 E102 D103	A95-K99 PolarHBondContact O-N 2.93Å; R96-K99 PolarHBondContact O-N 3.33Å; I97-K99 VanDerWaalsContact C-N 3.29Å; I97-K99 PolarHBondContact O-N 3.42Å; K99-M101 PolarHBondContact O-N 3.46Å; K99-E102 PolarHBondContact O-N 3.03Å; K99-D103 PolarHBondContact O-N 3.45Å
100	D	50.9	Low	50	Low	69 Å²	69	101.7 Å²	101.7	37%	0.369	54%	0.542	S	S	.	.	H	α-helix	trans	-67.6	-26.1	173.6	-70.1	-47	0	0	0	112	R96 S104	R96-D100 PolarHBondContact O-N 2.94Å; D100-S104 WeakPolarHBondContact O-CB 3.5Å; D100-S104 PolarHBondContact O-N 3.06Å; D100-S104 PolarHBondContact O-OG 2.95Å
101	M	46.9	Very low	51	Low	117 Å²	117	105.4 Å²	105.4	58%	0.576	55%	0.549	S	S	*	.	H	α-helix	trans	-73.8	-33.2	174.5	-169.2	159.5	58.9	0	0	113.4	I97 K99 S104 V105	I97-M101 WeakPolarHBondContact O-CB 3.38Å; I97-M101 PolarHBondContact O-N 3.05Å; I97-M101 VanDerWaalsContact O-N 3.09Å; K99-M101 PolarHBondContact O-N 3.46Å; M101-S104 WeakPolarHBondContact CA-OG 3.39Å; M101-S104 PolarHBondContact O-OG 3.32Å; M101-S104 VanDerWaalsContact O-OG 3.08Å; M101-V105 WeakPolarHBondContact O-CG2 3.34Å
102	E	45.2	Very low	52.1	Low	148 Å²	148	103.7 Å²	103.7	69%	0.692	54%	0.537	S	S	*	.	H	α-helix	trans	-71.7	-41.1	174	-71.2	-174.9	136	0	0	112.2	S98 K99 S104	S98-E102 PolarHBondContact O-N 3.35Å; K99-E102 PolarHBondContact O-N 3.03Å; E102-S104 VanDerWaalsContact C-N 3.31Å; E102-S104 PolarHBondContact O-N 3.17Å
103	D	52.4	Low	53	Low	112 Å²	112	102 Å²	102	60%	0.599	53%	0.532	S	S	*	.	H	α-helix	trans	-66.9	-29.1	178.4	-91.3	-17.4	0	0	0	113	K99	K99-D103 PolarHBondContact O-N 3.45Å
104	S	52.5	Low	54.1	Low	58 Å²	58	100.8 Å²	100.8	41%	0.406	53%	0.534	S	S	.	.	H	α-helix	trans	-75.9	-39.9	-179.7	40.6	0	0	0	0	113.1	D100 M101 E102 G106 L107	D100-S104 WeakPolarHBondContact O-CB 3.5Å; D100-S104 PolarHBondContact O-N 3.06Å; D100-S104 PolarHBondContact O-OG 2.95Å; M101-S104 WeakPolarHBondContact CA-OG 3.39Å; M101-S104 PolarHBondContact O-OG 3.32Å; M101-S104 VanDerWaalsContact O-OG 3.08Å; E102-S104 VanDerWaalsContact C-N 3.31Å; E102-S104 PolarHBondContact O-N 3.17Å; S104-G106 VanDerWaalsContact C-N 3.27Å; S104-G106 PolarHBondContact O-N 3.04Å; S104-L107 PolarHBondContact O-N 2.76Å; S104-L107 VanDerWaalsContact O-N 3.17Å
105	V	48.3	Very low	55.1	Low	110 Å²	110	101 Å²	101	67%	0.667	54%	0.536	S	S	*	.	H	α-helix	trans	-63.2	-32.8	177.9	176.5	0	0	0	0	112	M101 L107	M101-V105 WeakPolarHBondContact O-CG2 3.34Å; V105-L107 VanDerWaalsContact C-N 3.3Å; V105-L107 PolarHBondContact O-N 2.84Å
106	G	43.4	Very low	56.4	Low	53 Å²	53	101.7 Å²	101.7	55%	0.546	53%	0.534	S	S	.	.	H	α-helix	trans	-70.7	-18.1	177.3	0	0	0	0	0	115.4	S104	S104-G106 VanDerWaalsContact C-N 3.27Å; S104-G106 PolarHBondContact O-N 3.04Å
107	L	49.6	Very low	57.7	Low	112 Å²	112	98.1 Å²	98.1	59%	0.586	53%	0.529	S	S	*	.	H	α-helix	trans	-93.3	-33.2	-175.2	-72.7	168.8	0	0	0	113.4	S104 V105 C109 K110 R111	S104-L107 PolarHBondContact O-N 2.76Å; S104-L107 VanDerWaalsContact O-N 3.17Å; V105-L107 VanDerWaalsContact C-N 3.3Å; V105-L107 PolarHBondContact O-N 2.84Å; L107-C109 PolarHBondContact O-N 3.17Å; L107-K110 PolarHBondContact O-N 3.39Å; L107-R111 PolarHBondContact O-N 3.03Å
108	D	51.5	Low	59.1	Low	61 Å²	61	95.2 Å²	95.2	33%	0.326	52%	0.517	S	S	.	.	H	α-helix	trans	-66.2	-33.2	-175	-89.4	-35.3	0	0	0	113.4	K110 R111 Y112	D108-K110 VanDerWaalsContact C-N 3.29Å; D108-K110 PolarHBondContact O-N 3.3Å; D108-R111 VanDerWaalsContact O-CB 3.31Å; D108-R111 WeakPolarHBondContact O-CB 3.34Å; D108-R111 PolarHBondContact O-N 3.28Å; D108-R111 WeakPolarHBondContact OD1-CD 3.23Å; D108-R111 IonicContact OD1-CZ 2.68Å; D108-R111 IonicContact OD1-NE 3.32Å; D108-R111 IonicContact OD1-NH1 3.26Å; D108-R111 PolarHBondContact OD1-NH1 3.38Å; D108-Y112 HydrophobicContact CB-CD2 4.45Å; D108-Y112 HydrophobicContact CB-CE2 4.2Å; D108-Y112 WeakPolarHBondContact O-CD2 3.48Å; D108-Y112 PolarHBondContact O-N 3.49Å
109	C	53.1	Low	60.7	Low	103 Å²	103	94.5 Å²	94.5	70%	0.696	52%	0.515	S	S	*	.	H	α-helix	trans	-59.9	-38.3	177.4	-170.2	0	0	0	0	112.4	L107 L113	L107-C109 PolarHBondContact O-N 3.17Å; C109-L113 PolarHBondContact O-N 3.49Å
110	K	58	Low	62.4	Low	165 Å²	165	94 Å²	94	72%	0.717	51%	0.512	S	S	*	.	H	α-helix	trans	-72.7	-29.7	174.8	-71	177	179.4	168.9	0	112.8	L107 D108	L107-K110 PolarHBondContact O-N 3.39Å; D108-K110 VanDerWaalsContact C-N 3.29Å; D108-K110 PolarHBondContact O-N 3.3Å
111	R	61.1	Low	64.2	Low	122 Å²	122	91.3 Å²	91.3	46%	0.46	50%	0.498	S	S	.	.	H	α-helix	trans	-68.7	-46.7	177.8	-175.5	-172.4	178.3	-157.6	-0.8	111.4	L107 D108 L113 G114 D180	L107-R111 PolarHBondContact O-N 3.03Å; D108-R111 VanDerWaalsContact O-CB 3.31Å; D108-R111 WeakPolarHBondContact O-CB 3.34Å; D108-R111 PolarHBondContact O-N 3.28Å; D108-R111 WeakPolarHBondContact OD1-CD 3.23Å; D108-R111 IonicContact OD1-CZ 2.68Å; D108-R111 IonicContact OD1-NE 3.32Å; D108-R111 IonicContact OD1-NH1 3.26Å; D108-R111 PolarHBondContact OD1-NH1 3.38Å; R111-L113 PolarHBondContact O-N 3.29Å; R111-G114 PolarHBondContact O-N 3.08Å; R111-D180 IonicContact CZ-OD1 2.85Å; R111-D180 IonicContact CZ-OD2 3.05Å; R111-D180 IonicContact NE-OD1 3.34Å; R111-D180 PolarHBondContact NE-OD1 3.28Å; R111-D180 IonicContact NE-OD2 2.66Å; R111-D180 IonicContact NH2-OD1 2.69Å; R111-D180 PolarHBondContact NH2-OD1 3.35Å; R111-D180 IonicContact NH2-OD2 3.77Å; R111-D180 PolarHBondContact NH2-OD2 2.89Å
112	Y	65.8	Low	66.1	Low	137 Å²	137	87.4 Å²	87.4	54%	0.537	49%	0.488	S	S	.	.	H	α-helix	trans	-64.3	-38.3	174.9	-72.3	-70	0	0	0	112.3	D108 G114 L115 T116	D108-Y112 HydrophobicContact CB-CD2 4.45Å; D108-Y112 HydrophobicContact CB-CE2 4.2Å; D108-Y112 WeakPolarHBondContact O-CD2 3.48Å; D108-Y112 PolarHBondContact O-N 3.49Å; Y112-G114 VanDerWaalsContact C-N 3.31Å; Y112-G114 PolarHBondContact O-N 2.83Å; Y112-L115 PolarHBondContact O-N 2.95Å; Y112-L115 VanDerWaalsContact O-N 3.09Å; Y112-T116 WeakPolarHBondContact O-CG2 3.41Å; Y112-T116 PolarHBondContact O-N 2.95Å; Y112-T116 PolarHBondContact O-OG1 3.29Å
113	L	70.8	Confident	68.2	Low	107 Å²	107	85.1 Å²	85.1	56%	0.56	48%	0.48	S	S	*	.	H	α-helix	trans	-55.6	-41.8	179.1	-174.2	67.3	0	0	0	113.3	C109 R111 T116 V117	C109-L113 PolarHBondContact O-N 3.49Å; R111-L113 PolarHBondContact O-N 3.29Å; L113-T116 WeakPolarHBondContact CA-OG1 3.37Å; L113-T116 PolarHBondContact O-OG1 2.99Å; L113-T116 VanDerWaalsContact O-OG1 3.14Å; L113-V117 HydrophobicContact CD1-CG2 4.38Å; L113-V117 WeakPolarHBondContact O-CB 3.3Å; L113-V117 VanDerWaalsContact O-CG2 3.25Å; L113-V117 WeakPolarHBondContact O-CG2 3.47Å; L113-V117 PolarHBondContact O-N 3.1Å; L113-V117 VanDerWaalsContact O-N 3.08Å
114	G	72.8	Confident	70	Confident	39 Å²	39	82.4 Å²	82.4	40%	0.402	47%	0.465	S	S	.	.	H	α-helix	trans	-66	-38.6	177.4	0	0	0	0	0	113	R111 Y112 A118	R111-G114 PolarHBondContact O-N 3.08Å; Y112-G114 VanDerWaalsContact C-N 3.31Å; Y112-G114 PolarHBondContact O-N 2.83Å; G114-A118 WeakPolarHBondContact O-CB 3.46Å; G114-A118 PolarHBondContact O-N 3.14Å
115	L	75.4	Confident	71.8	Confident	105 Å²	105	80.1 Å²	80.1	55%	0.55	45%	0.449	S	S	.	.	H	α-helix	trans	-72.5	-42.3	178.3	-177.4	62.8	0	0	0	111.9	Y112 A118 A119	Y112-L115 PolarHBondContact O-N 2.95Å; Y112-L115 VanDerWaalsContact O-N 3.09Å; L115-A118 PolarHBondContact O-N 2.85Å; L115-A119 VanDerWaalsContact O-CB 3.28Å; L115-A119 WeakPolarHBondContact O-CB 3.37Å; L115-A119 PolarHBondContact O-N 3.42Å
116	T	79.2	Confident	73.9	Confident	78 Å²	78	78.1 Å²	78.1	48%	0.479	43%	0.431	S	S	.	.	H	α-helix	trans	-67.2	-40.9	179.2	55.1	0	0	0	0	111.8	Y112 L113 A119 F120	Y112-T116 WeakPolarHBondContact O-CG2 3.41Å; Y112-T116 PolarHBondContact O-N 2.95Å; Y112-T116 PolarHBondContact O-OG1 3.29Å; L113-T116 WeakPolarHBondContact CA-OG1 3.37Å; L113-T116 PolarHBondContact O-OG1 2.99Å; L113-T116 VanDerWaalsContact O-OG1 3.14Å; T116-A119 PolarHBondContact O-N 3.32Å; T116-F120 VanDerWaalsContact O-CB 3.23Å; T116-F120 WeakPolarHBondContact O-CB 3.4Å; T116-F120 PolarHBondContact O-N 3.49Å
117	V	81.6	Confident	76.3	Confident	80 Å²	80	79.5 Å²	79.5	49%	0.485	43%	0.425	S	S	.	.	H	α-helix	trans	-62.9	-44.1	174.2	170.4	0	0	0	0	111.3	L113 L121	L113-V117 HydrophobicContact CD1-CG2 4.38Å; L113-V117 WeakPolarHBondContact O-CB 3.3Å; L113-V117 VanDerWaalsContact O-CG2 3.25Å; L113-V117 WeakPolarHBondContact O-CG2 3.47Å; L113-V117 PolarHBondContact O-N 3.1Å; L113-V117 VanDerWaalsContact O-N 3.08Å; V117-L121 WeakPolarHBondContact O-CB 3.33Å; V117-L121 PolarHBondContact O-N 3.41Å
118	A	81.8	Confident	78.4	Confident	19 Å²	19	74.3 Å²	74.3	16%	0.157	40%	0.398	C	S	.	.	H	α-helix	trans	-65.8	-41.1	177.5	0	0	0	0	0	112.5	G114 L115 G122 L192	G114-A118 WeakPolarHBondContact O-CB 3.46Å; G114-A118 PolarHBondContact O-N 3.14Å; L115-A118 PolarHBondContact O-N 2.85Å; A118-G122 PolarHBondContact O-N 3.09Å; A118-L192 HydrophobicContact CB-CD1 4.28Å; A118-L192 HydrophobicContact CB-CD2 4.35Å
119	A	83.9	Confident	80.4	Confident	44 Å²	44	71.4 Å²	71.4	36%	0.364	38%	0.383	S	S	.	.	H	α-helix	trans	-66.8	-43.1	176.9	0	0	0	0	0	112.1	L115 T116 G122 L123	L115-A119 VanDerWaalsContact O-CB 3.28Å; L115-A119 WeakPolarHBondContact O-CB 3.37Å; L115-A119 PolarHBondContact O-N 3.42Å; T116-A119 PolarHBondContact O-N 3.32Å; A119-G122 PolarHBondContact O-N 3.2Å; A119-L123 WeakPolarHBondContact O-CB 3.29Å; A119-L123 PolarHBondContact O-N 2.96Å
120	F	87.3	Confident	82.3	Confident	134 Å²	134	69 Å²	69	59%	0.588	36%	0.362	S	S	*	.	H	α-helix	trans	-63.2	-45.2	176.1	179.4	-105.3	0	0	0	111.7	T116 G122 L123 L124	T116-F120 VanDerWaalsContact O-CB 3.23Å; T116-F120 WeakPolarHBondContact O-CB 3.4Å; T116-F120 PolarHBondContact O-N 3.49Å; F120-G122 VanDerWaalsContact C-N 3.35Å; F120-G122 PolarHBondContact O-N 3.11Å; F120-L123 WeakPolarHBondContact O-CB 3.21Å; F120-L123 PolarHBondContact O-N 3.19Å; F120-L124 HydrophobicContact CD1-CD1 3.98Å; F120-L124 HydrophobicContact CE1-CD1 3.48Å; F120-L124 VanDerWaalsContact CE1-CD1 3.48Å; F120-L124 HydrophobicContact CE1-CG 4.17Å; F120-L124 HydrophobicContact CZ-CD1 3.9Å; F120-L124 HydrophobicContact CZ-CD2 4.39Å; F120-L124 HydrophobicContact CZ-CG 4.21Å; F120-L124 WeakPolarHBondContact O-CG 3.46Å; F120-L124 PolarHBondContact O-N 3.17Å
121	L	87.6	Confident	84	Confident	14 Å²	14	62.5 Å²	62.5	7%	0.073	34%	0.34	C	S	.	.	H	α-helix	trans	-65.7	-38.2	176.2	-169.3	67	0	0	0	111.9	V117 L124 V125 L192 I195 F196	V117-L121 WeakPolarHBondContact O-CB 3.33Å; V117-L121 PolarHBondContact O-N 3.41Å; L121-L124 PolarHBondContact O-N 2.93Å; L121-V125 WeakPolarHBondContact O-CB 3.36Å; L121-V125 VanDerWaalsContact O-CG2 3.25Å; L121-V125 WeakPolarHBondContact O-CG2 3.47Å; L121-V125 PolarHBondContact O-N 3.19Å; L121-L192 HydrophobicContact CD2-CB 4.15Å; L121-L192 HydrophobicContact CD2-CD2 3.84Å; L121-L192 VanDerWaalsContact CD2-O 3.3Å; L121-L192 WeakPolarHBondContact CD2-O 3.34Å; L121-I195 HydrophobicContact CD1-CG2 4.38Å; L121-I195 HydrophobicContact CD2-CB 4.18Å; L121-I195 HydrophobicContact CD2-CG2 3.82Å; L121-I195 HydrophobicContact CG-CG2 3.96Å; L121-F196 HydrophobicContact CD1-CB 4.16Å; L121-F196 HydrophobicContact CD1-CD2 4.13Å; L121-F196 HydrophobicContact CD2-CB 4.31Å
122	G	87.1	Confident	85.5	Confident	34 Å²	34	56.7 Å²	56.7	35%	0.351	32%	0.318	S	S	.	.	H	α-helix	trans	-62.6	-41.1	173.7	0	0	0	0	0	113.2	A118 A119 F120 V125 F126	A118-G122 PolarHBondContact O-N 3.09Å; A119-G122 PolarHBondContact O-N 3.2Å; F120-G122 VanDerWaalsContact C-N 3.35Å; F120-G122 PolarHBondContact O-N 3.11Å; G122-V125 PolarHBondContact O-N 3.49Å; G122-F126 PolarHBondContact O-N 3.32Å
123	L	89.1	Confident	86.7	Confident	101 Å²	101	50.9 Å²	50.9	53%	0.529	30%	0.296	S	S	.	.	H	α-helix	trans	-61.9	-47.9	172.9	-172.1	95.3	0	0	0	111	A119 F120 V125 F126 L127	A119-L123 WeakPolarHBondContact O-CB 3.29Å; A119-L123 PolarHBondContact O-N 2.96Å; F120-L123 WeakPolarHBondContact O-CB 3.21Å; F120-L123 PolarHBondContact O-N 3.19Å; L123-V125 PolarHBondContact O-N 3Å; L123-F126 PolarHBondContact O-N 3.21Å; L123-L127 HydrophobicContact CD1-CD1 4.45Å; L123-L127 HydrophobicContact CD2-CD1 3.83Å; L123-L127 HydrophobicContact CG-CD1 3.77Å; L123-L127 HydrophobicContact CG-CG 4.37Å; L123-L127 WeakPolarHBondContact O-CB 3.25Å; L123-L127 WeakPolarHBondContact O-CG 3.41Å; L123-L127 PolarHBondContact O-N 3.44Å
124	L	90.1	Very high	87.7	Confident	55 Å²	55	50.3 Å²	50.3	29%	0.288	29%	0.293	S	S	.	.	H	α-helix	trans	-56	-51.8	175.7	-73.8	177.5	0	0	0	110.8	F120 L121 F126 L127 T128	F120-L124 HydrophobicContact CD1-CD1 3.98Å; F120-L124 HydrophobicContact CE1-CD1 3.48Å; F120-L124 VanDerWaalsContact CE1-CD1 3.48Å; F120-L124 HydrophobicContact CE1-CG 4.17Å; F120-L124 HydrophobicContact CZ-CD1 3.9Å; F120-L124 HydrophobicContact CZ-CD2 4.39Å; F120-L124 HydrophobicContact CZ-CG 4.21Å; F120-L124 WeakPolarHBondContact O-CG 3.46Å; F120-L124 PolarHBondContact O-N 3.17Å; L121-L124 PolarHBondContact O-N 2.93Å; L124-F126 PolarHBondContact O-N 3.49Å; L124-F126 VanDerWaalsContact O-N 3.14Å; L124-L127 PolarHBondContact O-N 3.4Å; L124-T128 VanDerWaalsContact O-CG2 3.29Å; L124-T128 WeakPolarHBondContact O-CG2 3.37Å; L124-T128 PolarHBondContact O-N 3Å; L124-T128 PolarHBondContact O-OG1 3.36Å
125	V	91.5	Very high	88.5	Confident	10 Å²	10	50.7 Å²	50.7	6%	0.061	29%	0.286	C	S	.	.	H	α-helix	trans	-53.1	-35.3	178.9	162.8	0	0	0	0	113.5	L121 G122 L123 P129 L165 I195 V199 L232	L121-V125 WeakPolarHBondContact O-CB 3.36Å; L121-V125 VanDerWaalsContact O-CG2 3.25Å; L121-V125 WeakPolarHBondContact O-CG2 3.47Å; L121-V125 PolarHBondContact O-N 3.19Å; G122-V125 PolarHBondContact O-N 3.49Å; L123-V125 PolarHBondContact O-N 3Å; V125-P129 WeakPolarHBondContact O-CD 3.17Å; V125-L165 HydrophobicContact CG1-CD2 3.97Å; V125-I195 HydrophobicContact CG2-CG2 3.29Å; V125-V199 HydrophobicContact CG2-CG2 3.96Å; V125-L232 HydrophobicContact CG1-CD1 4.02Å; V125-L232 HydrophobicContact CG1-CD2 3.92Å; V125-L232 HydrophobicContact CG1-CG 4.45Å; V125-L232 HydrophobicContact CG2-CD2 4.15Å
126	F	91.6	Very high	89.1	Confident	67 Å²	67	45.7 Å²	45.7	29%	0.294	26%	0.259	S	S	.	.	H	α-helix	trans	-80.1	-36.9	176.5	-173.8	-98.3	0	0	0	112.8	G122 L123 L124 P129 I130 L162 L166	G122-F126 PolarHBondContact O-N 3.32Å; L123-F126 PolarHBondContact O-N 3.21Å; L124-F126 PolarHBondContact O-N 3.49Å; L124-F126 VanDerWaalsContact O-N 3.14Å; F126-P129 WeakPolarHBondContact O-CD 3.47Å; F126-I130 HydrophobicContact CD1-CD1 4Å; F126-I130 HydrophobicContact CE1-CD1 3.62Å; F126-I130 HydrophobicContact CZ-CD1 4.1Å; F126-I130 WeakPolarHBondContact O-CD1 3.46Å; F126-L162 HydrophobicContact CD2-CD2 4.47Å; F126-L162 HydrophobicContact CE2-CB 4.19Å; F126-L166 HydrophobicContact CD2-CB 4.37Å; F126-L166 HydrophobicContact CD2-CD1 4.29Å; F126-L166 HydrophobicContact CE2-CB 4.05Å; F126-L166 HydrophobicContact CE2-CD1 4.28Å; F126-L166 HydrophobicContact CE2-CD2 4.28Å; F126-L166 HydrophobicContact CE2-CG 4.44Å; F126-L166 HydrophobicContact CZ-CD2 4.48Å
127	L	93.1	Very high	89.4	Confident	82 Å²	82	43.8 Å²	43.8	43%	0.429	25%	0.248	S	C	.	.	H	α-helix	trans	-79.1	-28.5	-178.4	-68.3	177.1	0	0	0	113.7	L123 L124 I130 A131	L123-L127 HydrophobicContact CD1-CD1 4.45Å; L123-L127 HydrophobicContact CD2-CD1 3.83Å; L123-L127 HydrophobicContact CG-CD1 3.77Å; L123-L127 HydrophobicContact CG-CG 4.37Å; L123-L127 WeakPolarHBondContact O-CB 3.25Å; L123-L127 WeakPolarHBondContact O-CG 3.41Å; L123-L127 PolarHBondContact O-N 3.44Å; L124-L127 PolarHBondContact O-N 3.4Å; L127-I130 PolarHBondContact O-N 3.38Å; L127-A131 WeakPolarHBondContact O-CB 3.23Å; L127-A131 PolarHBondContact O-N 3.08Å
128	T	94.1	Very high	89.7	Confident	3 Å²	3	46.3 Å²	46.3	2%	0.018	26%	0.257	C	S	.	.	H	α-helix	trans	-62.9	-42.4	-175.4	52.6	0	0	0	0	114.6	L124 I130 A131 F132 V199 W203	L124-T128 VanDerWaalsContact O-CG2 3.29Å; L124-T128 WeakPolarHBondContact O-CG2 3.37Å; L124-T128 PolarHBondContact O-N 3Å; L124-T128 PolarHBondContact O-OG1 3.36Å; T128-I130 VanDerWaalsContact C-N 3.33Å; T128-I130 PolarHBondContact O-N 3.31Å; T128-A131 PolarHBondContact O-N 3.42Å; T128-F132 WeakPolarHBondContact O-CD1 3.26Å; T128-F132 WeakPolarHBondContact O-CG 3.29Å; T128-F132 PolarHBondContact O-N 3.09Å; T128-V199 HydrophobicContact CG2-CG1 3.95Å; T128-W203 HydrophobicContact CG2-CZ2 4.22Å
129	P	93.8	Very high	89.9	Confident	0 Å²	0	50.6 Å²	50.6	0%	0	28%	0.277	C	S	.	.	H	α-helix	trans	-72.4	-31.4	179.4	-17.2	35.2	0	0	0	111.6	V125 F126 F132 I133 L162 L228 V229 L232	V125-P129 WeakPolarHBondContact O-CD 3.17Å; F126-P129 WeakPolarHBondContact O-CD 3.47Å; P129-F132 PolarHBondContact O-N 3.26Å; P129-I133 WeakPolarHBondContact O-CG1 3.25Å; P129-I133 PolarHBondContact O-N 2.91Å; P129-L162 HydrophobicContact CB-CD2 4.3Å; P129-L162 HydrophobicContact CG-CD2 4.07Å; P129-L228 HydrophobicContact CG-CD2 4.07Å; P129-L228 HydrophobicContact CG-CG 4.39Å; P129-V229 HydrophobicContact CB-CG2 3.47Å; P129-V229 VanDerWaalsContact CB-CG2 3.47Å; P129-V229 HydrophobicContact CG-CG2 3.65Å; P129-L232 HydrophobicContact CG-CD1 4.36Å
130	I	93.1	Very high	90	Very high	52 Å²	52	49.4 Å²	49.4	27%	0.267	26%	0.263	S	S	.	.	H	α-helix	trans	-65.4	-45.4	173.4	-59.5	174	0	0	0	109.7	F126 L127 T128 F132 I133 L134 L162	F126-I130 HydrophobicContact CD1-CD1 4Å; F126-I130 HydrophobicContact CE1-CD1 3.62Å; F126-I130 HydrophobicContact CZ-CD1 4.1Å; F126-I130 WeakPolarHBondContact O-CD1 3.46Å; L127-I130 PolarHBondContact O-N 3.38Å; T128-I130 VanDerWaalsContact C-N 3.33Å; T128-I130 PolarHBondContact O-N 3.31Å; I130-F132 PolarHBondContact O-N 3.16Å; I130-I133 PolarHBondContact O-N 3.33Å; I130-L134 HydrophobicContact CG2-CD1 3.67Å; I130-L134 HydrophobicContact CG2-CG 4.25Å; I130-L134 WeakPolarHBondContact O-CG 3.17Å; I130-L134 PolarHBondContact O-N 3.18Å; I130-L162 HydrophobicContact CD1-CD1 4.41Å; I130-L162 HydrophobicContact CG1-CD1 3.88Å
131	A	92.8	Very high	89.6	Confident	29 Å²	29	51.8 Å²	51.8	24%	0.24	27%	0.268	C	S	.	.	H	α-helix	trans	-60.5	-44.7	176.2	0	0	0	0	0	111.9	L127 T128 I133 L134 L135 W203	L127-A131 WeakPolarHBondContact O-CB 3.23Å; L127-A131 PolarHBondContact O-N 3.08Å; T128-A131 PolarHBondContact O-N 3.42Å; A131-I133 PolarHBondContact O-N 3.07Å; A131-L134 PolarHBondContact O-N 2.77Å; A131-L135 WeakPolarHBondContact O-CB 3.41Å; A131-L135 PolarHBondContact O-N 3.14Å; A131-W203 HydrophobicContact CB-CH2 4.33Å; A131-W203 HydrophobicContact CB-CZ2 4.33Å
132	F	93.2	Very high	89.1	Confident	0 Å²	0	59.5 Å²	59.5	0%	0	30%	0.304	C	S	.	.	H	α-helix	trans	-61.3	-27.9	178.8	-72.6	3.2	0	0	0	113.6	T128 P129 I130 P136 W203 Y206 I221 Y224 A225 L228	T128-F132 WeakPolarHBondContact O-CD1 3.26Å; T128-F132 WeakPolarHBondContact O-CG 3.29Å; T128-F132 PolarHBondContact O-N 3.09Å; P129-F132 PolarHBondContact O-N 3.26Å; I130-F132 PolarHBondContact O-N 3.16Å; F132-P136 WeakPolarHBondContact O-CD 3.45Å; F132-W203 HydrophobicContact CD1-CH2 4.42Å; F132-W203 HydrophobicContact CD1-CZ2 4.49Å; F132-W203 AromaticContact CE1-CD2 3.67Å; F132-W203 HydrophobicContact CE1-CD2 3.67Å; F132-W203 AromaticContact CE1-CE2 3.77Å; F132-W203 AromaticContact CE1-CE3 3.78Å; F132-W203 HydrophobicContact CE1-CE3 3.78Å; F132-W203 HydrophobicContact CE1-CG 4.23Å; F132-W203 HydrophobicContact CE1-CH2 4.07Å; F132-W203 AromaticContact CE1-CZ2 3.97Å; F132-W203 HydrophobicContact CE1-CZ2 3.97Å; F132-W203 AromaticContact CE1-CZ3 3.98Å; F132-W203 HydrophobicContact CE1-CZ3 3.98Å; F132-W203 HydrophobicContact CZ-CD2 4.17Å; F132-W203 HydrophobicContact CZ-CG 4.25Å; F132-Y206 HydrophobicContact CB-CD2 4.12Å; F132-Y206 HydrophobicContact CB-CE2 3.65Å; F132-Y206 AromaticContact CD1-CD1 3.83Å; F132-Y206 HydrophobicContact CD1-CD1 3.83Å; F132-Y206 AromaticContact CD1-CD2 3.69Å; F132-Y206 HydrophobicContact CD1-CD2 3.69Å; F132-Y206 AromaticContact CD1-CE1 3.89Å; F132-Y206 HydrophobicContact CD1-CE1 3.89Å; F132-Y206 AromaticContact CD1-CE2 3.79Å; F132-Y206 HydrophobicContact CD1-CE2 3.79Å; F132-Y206 AromaticContact CD1-CG 3.74Å; F132-Y206 HydrophobicContact CD1-CG 3.74Å; F132-Y206 AromaticContact CD1-CZ 3.9Å; F132-Y206 AromaticContact CD2-CD2 3.77Å; F132-Y206 HydrophobicContact CD2-CD2 3.77Å; F132-Y206 HydrophobicContact CD2-CE2 4.21Å; F132-Y206 HydrophobicContact CD2-CG 4.32Å; F132-Y206 AromaticContact CE1-CD1 3.75Å; F132-Y206 HydrophobicContact CE1-CD1 3.75Å; F132-Y206 AromaticContact CE1-CD2 3.97Å; F132-Y206 HydrophobicContact CE1-CD2 3.97Å; F132-Y206 HydrophobicContact CE1-CE1 4.27Å; F132-Y206 HydrophobicContact CE1-CE2 4.49Å; F132-Y206 AromaticContact CE1-CG 3.6Å; F132-Y206 HydrophobicContact CE1-CG 3.6Å; F132-Y206 HydrophobicContact CE2-CD2 4.05Å; F132-Y206 HydrophobicContact CE2-CG 4.2Å; F132-Y206 AromaticContact CG-CD2 3.59Å; F132-Y206 HydrophobicContact CG-CD2 3.59Å; F132-Y206 AromaticContact CG-CE2 3.63Å; F132-Y206 HydrophobicContact CG-CE2 3.63Å; F132-Y206 HydrophobicContact CG-CG 4.11Å; F132-Y206 HydrophobicContact CZ-CD1 4.42Å; F132-Y206 HydrophobicContact CZ-CD2 4.15Å; F132-Y206 AromaticContact CZ-CG 3.85Å; F132-Y206 HydrophobicContact CZ-CG 3.85Å; F132-Y206 PolarHBondContact O-OH 2.84Å; F132-Y206 VanDerWaalsContact O-OH 3.1Å; F132-I221 WeakPolarHBondContact O-CG2 3.5Å; F132-Y224 HydrophobicContact CD2-CD1 4.12Å; F132-Y224 HydrophobicContact CD2-CE1 4.04Å; F132-Y224 HydrophobicContact CE2-CD1 4.27Å; F132-Y224 AromaticContact CE2-CE1 3.71Å; F132-Y224 HydrophobicContact CE2-CE1 3.71Å; F132-A225 HydrophobicContact CB-CB 4.1Å; F132-L228 HydrophobicContact CD2-CD2 3.99Å; F132-L228 HydrophobicContact CE2-CD2 3.64Å; F132-L228 HydrophobicContact CZ-CD2 4.37Å
133	I	91.7	Very high	88.7	Confident	16 Å²	16	61.6 Å²	61.6	8%	0.082	31%	0.305	C	S	.	.	H	α-helix	trans	-85.9	-41.4	178.6	-65.4	170.3	0	0	0	111.2	P129 I130 A131 P137 L155 V158 Y218 A225	P129-I133 WeakPolarHBondContact O-CG1 3.25Å; P129-I133 PolarHBondContact O-N 2.91Å; I130-I133 PolarHBondContact O-N 3.33Å; A131-I133 PolarHBondContact O-N 3.07Å; I133-P137 WeakPolarHBondContact O-CD 3.38Å; I133-L155 HydrophobicContact CD1-CD2 4.16Å; I133-L155 HydrophobicContact CG2-CD2 3.69Å; I133-V158 HydrophobicContact CD1-CB 4.39Å; I133-V158 HydrophobicContact CD1-CG1 3.87Å; I133-V158 HydrophobicContact CD1-CG2 4.25Å; I133-Y218 VanDerWaalsContact CG2-OH 3.31Å; I133-Y218 WeakPolarHBondContact CG2-OH 3.46Å; I133-A225 HydrophobicContact CD1-CB 4.04Å; I133-A225 HydrophobicContact CG1-CB 3.73Å
134	L	91	Very high	88.4	Confident	94 Å²	94	58.3 Å²	58.3	49%	0.492	29%	0.287	S	S	.	.	H	α-helix	trans	-84.6	-26.9	-174.4	-65	-178	0	0	0	114.5	I130 A131 P137 I138	I130-L134 HydrophobicContact CG2-CD1 3.67Å; I130-L134 HydrophobicContact CG2-CG 4.25Å; I130-L134 WeakPolarHBondContact O-CG 3.17Å; I130-L134 PolarHBondContact O-N 3.18Å; A131-L134 PolarHBondContact O-N 2.77Å; L134-P137 VanDerWaalsContact O-CD 3.28Å; L134-P137 WeakPolarHBondContact O-CD 3.5Å; L134-P137 WeakPolarHBondContact O-CG 3.42Å; L134-I138 HydrophobicContact CB-CD1 4.31Å; L134-I138 VanDerWaalsContact O-CD1 3.3Å; L134-I138 WeakPolarHBondContact O-CD1 3.27Å; L134-I138 WeakPolarHBondContact O-CG1 3.42Å; L134-I138 PolarHBondContact O-N 2.99Å
135	L	90.2	Very high	88.1	Confident	48 Å²	48	61 Å²	61	25%	0.251	30%	0.297	S	S	.	.	H	α-helix	trans	-70.8	-36.5	-170.2	-169.2	146.5	0	0	0	113.9	A131 I138 L139 Y206 L211	A131-L135 WeakPolarHBondContact O-CB 3.41Å; A131-L135 PolarHBondContact O-N 3.14Å; L135-I138 PolarHBondContact O-N 3.41Å; L135-L139 HydrophobicContact CD2-CD1 3.48Å; L135-L139 VanDerWaalsContact CD2-CD1 3.48Å; L135-L139 HydrophobicContact CD2-CG 4.39Å; L135-L139 HydrophobicContact CG-CD1 4.19Å; L135-L139 WeakPolarHBondContact O-CG 3.44Å; L135-L139 PolarHBondContact O-N 3.34Å; L135-L139 VanDerWaalsContact O-N 3.14Å; L135-Y206 HydrophobicContact CD2-CE1 4.32Å; L135-L211 HydrophobicContact CD2-CD1 3.99Å; L135-L211 HydrophobicContact CD2-CD2 3.36Å; L135-L211 HydrophobicContact CD2-CG 4.33Å
136	P	87.7	Confident	87.5	Confident	0 Å²	0	66.7 Å²	66.7	0%	0	33%	0.334	C	S	.	.	H	α-helix	trans	-63.7	-50.3	173.3	-23.1	36.2	0	0	0	114.6	F132 I138 L139 W140 L144 Y206 I221	F132-P136 WeakPolarHBondContact O-CD 3.45Å; P136-I138 PolarHBondContact O-N 3.19Å; P136-L139 PolarHBondContact O-N 3.06Å; P136-W140 HydrophobicContact CB-CH2 4.05Å; P136-W140 HydrophobicContact CB-CZ2 3.92Å; P136-W140 PolarHBondContact O-N 3.42Å; P136-L144 HydrophobicContact CB-CD1 4.22Å; P136-L144 HydrophobicContact CB-CD2 4.35Å; P136-Y206 VanDerWaalsContact CD-OH 3.26Å; P136-Y206 WeakPolarHBondContact CD-OH 3.4Å; P136-Y206 VanDerWaalsContact CG-OH 3.25Å; P136-Y206 WeakPolarHBondContact CG-OH 3.43Å; P136-I221 HydrophobicContact CB-CD1 4.01Å; P136-I221 HydrophobicContact CG-CD1 3.87Å; P136-I221 HydrophobicContact CG-CG2 4.11Å
137	P	85.7	Confident	87.1	Confident	38 Å²	38	65.3 Å²	65.3	25%	0.247	33%	0.332	C	S	.	.	H	α-helix	trans	-69.5	-9.9	177.4	28	-35.1	0	0	0	114.2	I133 L134 R141 L144	I133-P137 WeakPolarHBondContact O-CD 3.38Å; L134-P137 VanDerWaalsContact O-CD 3.28Å; L134-P137 WeakPolarHBondContact O-CD 3.5Å; L134-P137 WeakPolarHBondContact O-CG 3.42Å; P137-R141 WeakPolarHBondContact O-CB 3.4Å; P137-L144 HydrophobicContact CB-CD1 4.22Å
138	I	88.1	Confident	86.8	Confident	132 Å²	132	63.5 Å²	63.5	68%	0.677	33%	0.334	S	S	*	.	H	α-helix	trans	-82.2	-38.2	168	-70.8	167.4	0	0	0	111.4	L134 L135 P136	L134-I138 HydrophobicContact CB-CD1 4.31Å; L134-I138 VanDerWaalsContact O-CD1 3.3Å; L134-I138 WeakPolarHBondContact O-CD1 3.27Å; L134-I138 WeakPolarHBondContact O-CG1 3.42Å; L134-I138 PolarHBondContact O-N 2.99Å; L135-I138 PolarHBondContact O-N 3.41Å; P136-I138 PolarHBondContact O-N 3.19Å
139	L	85.8	Confident	86.4	Confident	109 Å²	109	67.1 Å²	67.1	57%	0.571	36%	0.364	S	S	*	.	H	α-helix	trans	-89.1	-37.2	-173.2	-69.9	176	0	0	0	114.8	L135 P136 L211	L135-L139 HydrophobicContact CD2-CD1 3.48Å; L135-L139 VanDerWaalsContact CD2-CD1 3.48Å; L135-L139 HydrophobicContact CD2-CG 4.39Å; L135-L139 HydrophobicContact CG-CD1 4.19Å; L135-L139 WeakPolarHBondContact O-CG 3.44Å; L135-L139 PolarHBondContact O-N 3.34Å; L135-L139 VanDerWaalsContact O-N 3.14Å; P136-L139 PolarHBondContact O-N 3.06Å; L139-L211 HydrophobicContact CD1-CD2 4.4Å
140	W	86	Confident	86.2	Confident	20 Å²	20	73.1 Å²	73.1	8%	0.076	40%	0.395	C	S	.	.			trans	-148	50.7	-172.8	32.8	-87.5	0	0	0	112.5	P136 E142 E143 L144 R214 D215 I221	P136-W140 HydrophobicContact CB-CH2 4.05Å; P136-W140 HydrophobicContact CB-CZ2 3.92Å; P136-W140 PolarHBondContact O-N 3.42Å; W140-E142 VanDerWaalsContact C-N 3.3Å; W140-E142 PolarHBondContact O-N 3.36Å; W140-E143 HydrophobicContact CB-CB 4.44Å; W140-E143 HydrophobicContact CE3-CB 4.39Å; W140-E143 PolarHBondContact O-N 3.44Å; W140-L144 HydrophobicContact CE3-CD1 3.96Å; W140-L144 HydrophobicContact CE3-CD2 4.22Å; W140-L144 HydrophobicContact CE3-CG 3.74Å; W140-L144 HydrophobicContact CH2-CD2 4.41Å; W140-L144 HydrophobicContact CZ3-CD1 4.26Å; W140-L144 HydrophobicContact CZ3-CD2 3.71Å; W140-L144 HydrophobicContact CZ3-CG 3.75Å; W140-R214 HydrophobicContact CZ2-CB 4.4Å; W140-D215 WeakPolarHBondContact CH2-O 3.43Å; W140-D215 VanDerWaalsContact CZ3-O 3.27Å; W140-D215 WeakPolarHBondContact CZ3-O 3.05Å; W140-I221 HydrophobicContact CH2-CD1 4.02Å
141	R	78.3	Confident	86	Confident	183 Å²	183	70.8 Å²	70.8	69%	0.691	38%	0.383	S	S	*	.	G	3₁₀ helix	trans	-47.7	-44.7	-176.8	-162.5	-179.8	-135.4	-153.7	1.5	114.9	P137 E143 L144	P137-R141 WeakPolarHBondContact O-CB 3.4Å; R141-E143 VanDerWaalsContact C-N 3.25Å; R141-E143 PolarHBondContact O-N 2.66Å; R141-L144 PolarHBondContact O-N 3.34Å
142	E	78	Confident	85.8	Confident	177 Å²	177	74.5 Å²	74.5	83%	0.827	40%	0.396	S	S	*	.	G	3₁₀ helix	trans	-73	-15.2	-174.9	-53	-55.7	143.1	0	0	113.4	W140	W140-E142 VanDerWaalsContact C-N 3.3Å; W140-E142 PolarHBondContact O-N 3.36Å
143	E	78.1	Confident	85.7	Confident	78 Å²	78	76.4 Å²	76.4	36%	0.364	42%	0.415	S	S	.	.	G	3₁₀ helix	trans	-94.8	-7.3	179.9	-62.5	178.7	-159.2	0	0	112.7	W140 R141 R214 Q216	W140-E143 HydrophobicContact CB-CB 4.44Å; W140-E143 HydrophobicContact CE3-CB 4.39Å; W140-E143 PolarHBondContact O-N 3.44Å; R141-E143 VanDerWaalsContact C-N 3.25Å; R141-E143 PolarHBondContact O-N 2.66Å; E143-R214 IonicContact OE1-NH1 3.51Å; E143-R214 IonicContact OE2-NH1 3.88Å; E143-Q216 WeakPolarHBondContact O-CB 3.46Å; E143-Q216 VanDerWaalsContact O-CG 3.23Å; E143-Q216 WeakPolarHBondContact O-CG 3.17Å
144	L	82.8	Confident	85.7	Confident	31 Å²	31	77.5 Å²	77.5	16%	0.162	42%	0.421	C	S	.	.	S	Bend	trans	-87.6	131.9	-174.8	-80.3	143.5	0	0	0	112.8	P136 P137 W140 R141 Y218 I221	P136-L144 HydrophobicContact CB-CD1 4.22Å; P136-L144 HydrophobicContact CB-CD2 4.35Å; P137-L144 HydrophobicContact CB-CD1 4.22Å; W140-L144 HydrophobicContact CE3-CD1 3.96Å; W140-L144 HydrophobicContact CE3-CD2 4.22Å; W140-L144 HydrophobicContact CE3-CG 3.74Å; W140-L144 HydrophobicContact CH2-CD2 4.41Å; W140-L144 HydrophobicContact CZ3-CD1 4.26Å; W140-L144 HydrophobicContact CZ3-CD2 3.71Å; W140-L144 HydrophobicContact CZ3-CG 3.75Å; R141-L144 PolarHBondContact O-N 3.34Å; L144-Y218 HydrophobicContact CD2-CD2 3.91Å; L144-Y218 HydrophobicContact CD2-CG 4.3Å; L144-I221 HydrophobicContact CD2-CD1 4.37Å
145	K	82.8	Confident	85.7	Confident	111 Å²	111	75.2 Å²	75.2	48%	0.483	41%	0.409	S	S	.	.	P	Polyproline II helix	trans	-69.9	141.9	172.7	-65.4	172.1	-169.3	162.8	0	110.8	Q216 N217	K145-Q216 PolarHBondContact N-O 2.99Å; K145-Q216 VanDerWaalsContact N-O 3.11Å; K145-N217 PolarHBondContact NZ-OD1 3.23Å
146	P	79.4	Confident	85.8	Confident	130 Å²	130	77.7 Å²	77.7	84%	0.844	42%	0.421	S	S	*	.	P	Polyproline II helix	trans	-61.7	139.6	179.8	24.8	-33.8	0	0	0	112.4	G148	P146-G148 PolarHBondContact O-N 3.26Å
147	C	83	Confident	86.1	Confident	38 Å²	38	79.6 Å²	79.6	26%	0.257	44%	0.435	S	S	.	.	P	Polyproline II helix	trans	-69.2	120	175.6	-174.1	0	0	0	0	109.5	C151 E152 Y218	C147-C151 HydrophobicContact CB-CB 4.11Å; C147-C151 WeakPolarHBondContact CB-SG 3.01Å; C147-C151 WeakPolarHBondContact SG-CB 3.43Å; C147-C151 CovalentContact SG-SG 2.04Å; C147-C151 PolarHBondContact SG-SG 2.9Å; C147-E152 PolarHBondContact SG-N 2.68Å; C147-E152 VanDerWaalsContact SG-N 3.4Å; C147-Y218 HydrophobicContact CB-CD1 3.85Å; C147-Y218 HydrophobicContact CB-CE1 4.13Å
148	G	86.9	Confident	86.5	Confident	45 Å²	45	78 Å²	78	46%	0.464	42%	0.424	S	S	.	.	P	Polyproline II helix	trans	-86.6	171.4	170.8	0	0	0	0	0	112.5	P146 I150 C151 E152	P146-G148 PolarHBondContact O-N 3.26Å; G148-I150 PolarHBondContact O-N 3.34Å; G148-C151 WeakPolarHBondContact O-CA 3.18Å; G148-C151 VanDerWaalsContact O-CB 3.3Å; G148-C151 WeakPolarHBondContact O-CB 3.38Å; G148-C151 PolarHBondContact O-N 3.12Å; G148-E152 PolarHBondContact O-N 2.83Å; G148-E152 VanDerWaalsContact O-N 3.1Å
149	A	87.3	Confident	86.7	Confident	79 Å²	79	75.4 Å²	75.4	65%	0.653	42%	0.417	S	S	*	.	H	α-helix	trans	-50.4	-32.6	-174.8	0	0	0	0	0	115.6	E152 G153	A149-E152 PolarHBondContact O-N 2.82Å; A149-G153 PolarHBondContact O-N 2.98Å
150	I	88.3	Confident	87.1	Confident	125 Å²	125	76.6 Å²	76.6	64%	0.641	42%	0.418	S	S	*	.	H	α-helix	trans	-64.7	-42.2	174.5	-60.3	173.2	0	0	0	111.1	G148 G153 L154	G148-I150 PolarHBondContact O-N 3.34Å; I150-G153 PolarHBondContact O-N 3.43Å; I150-L154 WeakPolarHBondContact O-CG 3.35Å; I150-L154 PolarHBondContact O-N 3.19Å; I150-L154 VanDerWaalsContact O-N 3.12Å
151	C	88.9	Confident	87.5	Confident	3 Å²	3	77.5 Å²	77.5	2%	0.02	42%	0.423	C	S	.	.	H	α-helix	trans	-69.6	-38.2	177.7	159.5	0	0	0	0	111.1	C147 G148 G153 L154 L155 Y218 K219	C147-C151 HydrophobicContact CB-CB 4.11Å; C147-C151 WeakPolarHBondContact CB-SG 3.01Å; C147-C151 WeakPolarHBondContact SG-CB 3.43Å; C147-C151 CovalentContact SG-SG 2.04Å; C147-C151 PolarHBondContact SG-SG 2.9Å; G148-C151 WeakPolarHBondContact O-CA 3.18Å; G148-C151 VanDerWaalsContact O-CB 3.3Å; G148-C151 WeakPolarHBondContact O-CB 3.38Å; G148-C151 PolarHBondContact O-N 3.12Å; C151-G153 PolarHBondContact O-N 2.83Å; C151-L154 WeakPolarHBondContact O-CB 3.34Å; C151-L154 PolarHBondContact O-N 2.87Å; C151-L155 PolarHBondContact O-N 3.48Å; C151-Y218 VanDerWaalsContact SG-CD1 3.59Å; C151-K219 HydrophobicContact CB-CB 4.31Å; C151-K219 HydrophobicContact CB-CG 4.34Å
152	E	89.1	Confident	88.2	Confident	108 Å²	108	69.5 Å²	69.5	51%	0.505	39%	0.394	S	S	.	.	H	α-helix	trans	-62.1	-42.6	172.2	-61.6	-179.5	145.1	0	0	111.7	C147 G148 A149 L154 L155 I156	C147-E152 PolarHBondContact SG-N 2.68Å; C147-E152 VanDerWaalsContact SG-N 3.4Å; G148-E152 PolarHBondContact O-N 2.83Å; G148-E152 VanDerWaalsContact O-N 3.1Å; A149-E152 PolarHBondContact O-N 2.82Å; E152-L154 VanDerWaalsContact C-N 3.29Å; E152-L154 PolarHBondContact O-N 3.29Å; E152-L155 WeakPolarHBondContact O-CB 3.22Å; E152-L155 PolarHBondContact O-N 3.39Å; E152-L155 VanDerWaalsContact O-N 3.15Å; E152-I156 WeakPolarHBondContact O-CG1 3.28Å; E152-I156 PolarHBondContact O-N 2.99Å
153	G	91.6	Very high	88.9	Confident	39 Å²	39	65.5 Å²	65.5	40%	0.402	38%	0.377	S	S	.	.	H	α-helix	trans	-59.7	-36.3	173.2	0	0	0	0	0	113.5	A149 I150 C151 S157	A149-G153 PolarHBondContact O-N 2.98Å; I150-G153 PolarHBondContact O-N 3.43Å; C151-G153 PolarHBondContact O-N 2.83Å; G153-S157 WeakPolarHBondContact O-CB 3.47Å; G153-S157 PolarHBondContact O-N 3.36Å
154	L	92	Very high	89.6	Confident	39 Å²	39	65.7 Å²	65.7	20%	0.204	38%	0.38	C	S	.	.	H	α-helix	trans	-67.9	-39.9	173.5	-67.9	174.5	0	0	0	112.2	I150 C151 E152 I156 S157 V158 V222 Q223 V226	I150-L154 WeakPolarHBondContact O-CG 3.35Å; I150-L154 PolarHBondContact O-N 3.19Å; I150-L154 VanDerWaalsContact O-N 3.12Å; C151-L154 WeakPolarHBondContact O-CB 3.34Å; C151-L154 PolarHBondContact O-N 2.87Å; E152-L154 VanDerWaalsContact C-N 3.29Å; E152-L154 PolarHBondContact O-N 3.29Å; L154-I156 PolarHBondContact O-N 2.91Å; L154-S157 WeakPolarHBondContact O-CB 3.21Å; L154-S157 PolarHBondContact O-N 2.95Å; L154-S157 VanDerWaalsContact O-N 3.17Å; L154-V158 WeakPolarHBondContact O-CG2 3.49Å; L154-V158 PolarHBondContact O-N 3.27Å; L154-V222 HydrophobicContact CB-CG1 3.65Å; L154-V222 HydrophobicContact CD1-CG1 4.43Å; L154-Q223 HydrophobicContact CD1-CB 4.21Å; L154-V226 HydrophobicContact CB-CG2 4.07Å; L154-V226 HydrophobicContact CD2-CG2 4.15Å
155	L	90.8	Very high	90	Very high	47 Å²	47	64.5 Å²	64.5	25%	0.246	37%	0.374	C	S	.	.	H	α-helix	trans	-62.6	-40.7	175.2	-68.4	171.4	0	0	0	112.3	I133 C151 E152 S157 V158 S159 Y218 V222	I133-L155 HydrophobicContact CD1-CD2 4.16Å; I133-L155 HydrophobicContact CG2-CD2 3.69Å; C151-L155 PolarHBondContact O-N 3.48Å; E152-L155 WeakPolarHBondContact O-CB 3.22Å; E152-L155 PolarHBondContact O-N 3.39Å; E152-L155 VanDerWaalsContact O-N 3.15Å; L155-S157 VanDerWaalsContact C-N 3.34Å; L155-V158 PolarHBondContact O-N 3.41Å; L155-S159 PolarHBondContact O-N 2.93Å; L155-S159 PolarHBondContact O-OG 2.87Å; L155-Y218 HydrophobicContact CD1-CE1 4.4Å; L155-V222 HydrophobicContact CD2-CG1 3.88Å; L155-V222 HydrophobicContact CD2-CG2 3.86Å; L155-V222 HydrophobicContact CG-CG1 4.12Å; L155-V222 HydrophobicContact CG-CG2 4.42Å
156	I	92.3	Very high	90.3	Very high	99 Å²	99	63.1 Å²	63.1	51%	0.508	37%	0.371	S	S	.	.	H	α-helix	trans	-62.2	-44.2	172.6	-65.2	166.9	0	0	0	109.8	E152 L154 S159 F160	E152-I156 WeakPolarHBondContact O-CG1 3.28Å; E152-I156 PolarHBondContact O-N 2.99Å; L154-I156 PolarHBondContact O-N 2.91Å; I156-S159 WeakPolarHBondContact O-CB 3.21Å; I156-S159 PolarHBondContact O-N 3.36Å; I156-F160 HydrophobicContact CG2-CD2 3.85Å; I156-F160 HydrophobicContact CG2-CE2 3.7Å; I156-F160 WeakPolarHBondContact O-CD2 3.3Å; I156-F160 PolarHBondContact O-N 3.29Å; I156-F160 VanDerWaalsContact O-N 3.14Å
157	S	93.3	Very high	90.8	Very high	41 Å²	41	61.7 Å²	61.7	29%	0.287	36%	0.356	S	S	.	.	H	α-helix	trans	-59.8	-46.7	177.1	-165.7	0	0	0	0	112.5	G153 L154 L155 S159 F160 K161	G153-S157 WeakPolarHBondContact O-CB 3.47Å; G153-S157 PolarHBondContact O-N 3.36Å; L154-S157 WeakPolarHBondContact O-CB 3.21Å; L154-S157 PolarHBondContact O-N 2.95Å; L154-S157 VanDerWaalsContact O-N 3.17Å; L155-S157 VanDerWaalsContact C-N 3.34Å; S157-S159 VanDerWaalsContact C-N 3.31Å; S157-S159 PolarHBondContact O-N 2.94Å; S157-F160 PolarHBondContact O-N 3.38Å; S157-K161 WeakPolarHBondContact O-CB 3.35Å; S157-K161 VanDerWaalsContact O-CG 3.23Å; S157-K161 WeakPolarHBondContact O-CG 3.4Å; S157-K161 PolarHBondContact O-N 2.9Å; S157-K161 VanDerWaalsContact OG-CE 3.31Å; S157-K161 WeakPolarHBondContact OG-CE 3.33Å
158	V	93.8	Very high	90.9	Very high	4 Å²	4	60.5 Å²	60.5	2%	0.024	35%	0.349	C	S	.	.	H	α-helix	trans	-56.8	-45.2	174	171.5	0	0	0	0	111.1	I133 L154 L155 F160 K161 L162 V226 V229	I133-V158 HydrophobicContact CD1-CB 4.39Å; I133-V158 HydrophobicContact CD1-CG1 3.87Å; I133-V158 HydrophobicContact CD1-CG2 4.25Å; L154-V158 WeakPolarHBondContact O-CG2 3.49Å; L154-V158 PolarHBondContact O-N 3.27Å; L155-V158 PolarHBondContact O-N 3.41Å; V158-F160 PolarHBondContact O-N 3.22Å; V158-K161 PolarHBondContact O-N 3.03Å; V158-L162 HydrophobicContact CG1-CD1 3.65Å; V158-L162 HydrophobicContact CG1-CG 4.02Å; V158-L162 WeakPolarHBondContact O-CB 3.45Å; V158-L162 WeakPolarHBondContact O-CG 3.46Å; V158-L162 PolarHBondContact O-N 3.1Å; V158-V226 HydrophobicContact CG2-CB 4.3Å; V158-V226 HydrophobicContact CG2-CG2 3.39Å; V158-V229 HydrophobicContact CG1-CG2 4.39Å
159	S	93.1	Very high	90.6	Very high	77 Å²	77	59.9 Å²	59.9	54%	0.538	34%	0.337	S	S	.	.	H	α-helix	trans	-59.5	-46.8	-178	-56.8	0	0	0	0	112.1	L155 I156 S157 L163	L155-S159 PolarHBondContact O-N 2.93Å; L155-S159 PolarHBondContact O-OG 2.87Å; I156-S159 WeakPolarHBondContact O-CB 3.21Å; I156-S159 PolarHBondContact O-N 3.36Å; S157-S159 VanDerWaalsContact C-N 3.31Å; S157-S159 PolarHBondContact O-N 2.94Å; S159-L163 PolarHBondContact O-N 3.44Å; S159-L163 VanDerWaalsContact O-N 3.12Å
160	F	93.9	Very high	90.5	Very high	134 Å²	134	64.3 Å²	64.3	59%	0.588	34%	0.337	S	S	*	.	H	α-helix	trans	-67.7	-40.6	175.2	-77.6	-70.5	0	0	0	112.9	I156 S157 V158 L163 I164	I156-F160 HydrophobicContact CG2-CD2 3.85Å; I156-F160 HydrophobicContact CG2-CE2 3.7Å; I156-F160 WeakPolarHBondContact O-CD2 3.3Å; I156-F160 PolarHBondContact O-N 3.29Å; I156-F160 VanDerWaalsContact O-N 3.14Å; S157-F160 PolarHBondContact O-N 3.38Å; V158-F160 PolarHBondContact O-N 3.22Å; F160-L163 WeakPolarHBondContact O-CB 3.35Å; F160-L163 PolarHBondContact O-N 3.33Å; F160-I164 WeakPolarHBondContact O-CG1 3.37Å; F160-I164 PolarHBondContact O-N 3.31Å
161	K	94.8	Very high	90.1	Very high	40 Å²	40	60.5 Å²	60.5	17%	0.174	32%	0.324	C	S	.	.	H	α-helix	trans	-64.1	-40.5	178.4	-73.4	174.5	-179.2	-177.8	0	112.2	S157 V158 I164 L165 V229 D230 L233	S157-K161 WeakPolarHBondContact O-CB 3.35Å; S157-K161 VanDerWaalsContact O-CG 3.23Å; S157-K161 WeakPolarHBondContact O-CG 3.4Å; S157-K161 PolarHBondContact O-N 2.9Å; S157-K161 VanDerWaalsContact OG-CE 3.31Å; S157-K161 WeakPolarHBondContact OG-CE 3.33Å; V158-K161 PolarHBondContact O-N 3.03Å; K161-I164 PolarHBondContact O-N 2.7Å; K161-L165 WeakPolarHBondContact O-CB 3.28Å; K161-L165 PolarHBondContact O-N 2.95Å; K161-V229 HydrophobicContact CB-CG1 3.47Å; K161-V229 VanDerWaalsContact CB-CG1 3.47Å; K161-V229 HydrophobicContact CD-CG1 4.24Å; K161-V229 HydrophobicContact CG-CG1 4.45Å; K161-D230 WeakPolarHBondContact CD-OD1 3.34Å; K161-D230 WeakPolarHBondContact CE-OD1 3.37Å; K161-D230 IonicContact NZ-OD1 3.48Å; K161-D230 PolarHBondContact NZ-OD1 2.77Å; K161-D230 IonicContact NZ-OD2 2.98Å; K161-D230 PolarHBondContact NZ-OD2 3.46Å; K161-L233 HydrophobicContact CB-CD1 3.75Å; K161-L233 HydrophobicContact CD-CD1 4.26Å; K161-L233 HydrophobicContact CG-CD1 3.78Å
162	L	92.6	Very high	89.3	Confident	15 Å²	15	61.3 Å²	61.3	8%	0.079	33%	0.328	C	S	.	.	H	α-helix	trans	-65.9	-38.1	174.1	-74.2	177.2	0	0	0	112.3	F126 P129 I130 V158 L165 L166 V229	F126-L162 HydrophobicContact CD2-CD2 4.47Å; F126-L162 HydrophobicContact CE2-CB 4.19Å; P129-L162 HydrophobicContact CB-CD2 4.3Å; P129-L162 HydrophobicContact CG-CD2 4.07Å; I130-L162 HydrophobicContact CD1-CD1 4.41Å; I130-L162 HydrophobicContact CG1-CD1 3.88Å; V158-L162 HydrophobicContact CG1-CD1 3.65Å; V158-L162 HydrophobicContact CG1-CG 4.02Å; V158-L162 WeakPolarHBondContact O-CB 3.45Å; V158-L162 WeakPolarHBondContact O-CG 3.46Å; V158-L162 PolarHBondContact O-N 3.1Å; L162-L165 PolarHBondContact O-N 3.45Å; L162-L166 WeakPolarHBondContact O-CB 3.19Å; L162-L166 PolarHBondContact O-N 3.18Å; L162-V229 HydrophobicContact CD2-CG1 4.37Å; L162-V229 HydrophobicContact CD2-CG2 4.08Å; L162-V229 HydrophobicContact CG-CG2 4.43Å
163	L	92.8	Very high	88.3	Confident	92 Å²	92	59 Å²	59	48%	0.482	32%	0.317	S	S	.	.	H	α-helix	trans	-60.5	-46.3	173.3	-174.5	78.3	0	0	0	111.4	S159 F160 L166 I167	S159-L163 PolarHBondContact O-N 3.44Å; S159-L163 VanDerWaalsContact O-N 3.12Å; F160-L163 WeakPolarHBondContact O-CB 3.35Å; F160-L163 PolarHBondContact O-N 3.33Å; L163-L166 PolarHBondContact O-N 2.88Å; L163-I167 HydrophobicContact CG-CD1 4.13Å; L163-I167 WeakPolarHBondContact O-CG1 3.18Å; L163-I167 PolarHBondContact O-N 3.44Å
164	I	92.2	Very high	87	Confident	83 Å²	83	63.8 Å²	63.8	43%	0.426	33%	0.327	S	S	.	.	H	α-helix	trans	-61.7	-45.4	176.7	-67	165.3	0	0	0	110.5	F160 K161 L166 I167 G168 L233	F160-I164 WeakPolarHBondContact O-CG1 3.37Å; F160-I164 PolarHBondContact O-N 3.31Å; K161-I164 PolarHBondContact O-N 2.7Å; I164-L166 VanDerWaalsContact C-N 3.34Å; I164-L166 PolarHBondContact O-N 2.88Å; I164-I167 PolarHBondContact O-N 3.17Å; I164-G168 PolarHBondContact O-N 3.25Å; I164-L233 HydrophobicContact CG2-CD2 4.02Å
165	L	90.8	Very high	85.8	Confident	6 Å²	6	69.7 Å²	69.7	3%	0.031	35%	0.346	C	S	.	.	H	α-helix	trans	-63.1	-38	178.2	-170.8	67.1	0	0	0	112.1	V125 K161 L162 T169 L232 L233 H236	V125-L165 HydrophobicContact CG1-CD2 3.97Å; K161-L165 WeakPolarHBondContact O-CB 3.28Å; K161-L165 PolarHBondContact O-N 2.95Å; L162-L165 PolarHBondContact O-N 3.45Å; L165-T169 HydrophobicContact CD1-CG2 4.4Å; L165-T169 HydrophobicContact CG-CG2 4.47Å; L165-T169 WeakPolarHBondContact O-CB 3.41Å; L165-T169 VanDerWaalsContact O-CG2 3.28Å; L165-T169 WeakPolarHBondContact O-CG2 3.48Å; L165-T169 PolarHBondContact O-N 2.98Å; L165-T169 PolarHBondContact O-OG1 3.37Å; L165-L232 HydrophobicContact CD2-CB 4.05Å; L165-L232 HydrophobicContact CD2-CD1 4.38Å; L165-L233 HydrophobicContact CB-CD2 4.09Å; L165-L233 HydrophobicContact CD1-CD2 4.12Å; L165-H236 HydrophobicContact CD1-CB 3.97Å
166	L	89.7	Confident	84.2	Confident	81 Å²	81	76.3 Å²	76.3	42%	0.424	37%	0.373	S	S	.	.	H	α-helix	trans	-64.7	-48.9	175.8	-178.4	66	0	0	0	111.8	F126 L162 L163 I164 G168 T169 W170	F126-L166 HydrophobicContact CD2-CB 4.37Å; F126-L166 HydrophobicContact CD2-CD1 4.29Å; F126-L166 HydrophobicContact CE2-CB 4.05Å; F126-L166 HydrophobicContact CE2-CD1 4.28Å; F126-L166 HydrophobicContact CE2-CD2 4.28Å; F126-L166 HydrophobicContact CE2-CG 4.44Å; F126-L166 HydrophobicContact CZ-CD2 4.48Å; L162-L166 WeakPolarHBondContact O-CB 3.19Å; L162-L166 PolarHBondContact O-N 3.18Å; L163-L166 PolarHBondContact O-N 2.88Å; I164-L166 VanDerWaalsContact C-N 3.34Å; I164-L166 PolarHBondContact O-N 2.88Å; L166-G168 VanDerWaalsContact C-N 3.34Å; L166-G168 PolarHBondContact O-N 3.44Å; L166-T169 PolarHBondContact O-OG1 3.42Å; L166-T169 VanDerWaalsContact O-OG1 3.09Å; L166-W170 WeakPolarHBondContact O-CB 3.33Å; L166-W170 PolarHBondContact O-N 3.39Å
167	I	88.9	Confident	82.4	Confident	101 Å²	101	77.1 Å²	77.1	52%	0.518	37%	0.374	S	S	.	.	H	α-helix	trans	-62.6	-43.4	177.6	-66	167.3	0	0	0	110.4	L163 I164 W170 A171	L163-I167 HydrophobicContact CG-CD1 4.13Å; L163-I167 WeakPolarHBondContact O-CG1 3.18Å; L163-I167 PolarHBondContact O-N 3.44Å; I164-I167 PolarHBondContact O-N 3.17Å; I167-W170 PolarHBondContact O-N 2.89Å; I167-A171 WeakPolarHBondContact O-CB 3.26Å; I167-A171 PolarHBondContact O-N 3.4Å
168	G	85.2	Confident	80.6	Confident	12 Å²	12	85.6 Å²	85.6	12%	0.124	40%	0.4	C	S	.	.	H	α-helix	trans	-65.3	-45.4	179	0	0	0	0	0	113.4	I164 L166 A171 L172 H236	I164-G168 PolarHBondContact O-N 3.25Å; L166-G168 VanDerWaalsContact C-N 3.34Å; L166-G168 PolarHBondContact O-N 3.44Å; G168-A171 PolarHBondContact O-N 3.44Å; G168-L172 PolarHBondContact O-N 3.04Å; G168-H236 VanDerWaalsContact CA-CE1 3.5Å; G168-H236 WeakPolarHBondContact CA-CE1 3.38Å; G168-H236 VanDerWaalsContact CA-NE2 3.35Å; G168-H236 WeakPolarHBondContact CA-NE2 3.42Å; G168-H236 PolarHBondContact O-CE1 2.87Å; G168-H236 VanDerWaalsContact O-CE1 3.3Å
169	T	82.5	Confident	78.9	Confident	32 Å²	32	87 Å²	87	20%	0.196	41%	0.412	C	S	.	.	H	α-helix	trans	-66.1	-39.1	176.5	49.8	0	0	0	0	111.8	L165 L166 L172 F173	L165-T169 HydrophobicContact CD1-CG2 4.4Å; L165-T169 HydrophobicContact CG-CG2 4.47Å; L165-T169 WeakPolarHBondContact O-CB 3.41Å; L165-T169 VanDerWaalsContact O-CG2 3.28Å; L165-T169 WeakPolarHBondContact O-CG2 3.48Å; L165-T169 PolarHBondContact O-N 2.98Å; L165-T169 PolarHBondContact O-OG1 3.37Å; L166-T169 PolarHBondContact O-OG1 3.42Å; L166-T169 VanDerWaalsContact O-OG1 3.09Å; T169-L172 PolarHBondContact O-N 3.47Å; T169-F173 WeakPolarHBondContact O-CB 3.42Å; T169-F173 WeakPolarHBondContact O-CD2 3.41Å; T169-F173 PolarHBondContact O-N 2.87Å
170	W	84	Confident	77.1	Confident	172 Å²	172	88.1 Å²	88.1	65%	0.652	41%	0.412	S	S	*	.	I	π-helix	trans	-57.8	-49.6	170.2	179.7	79.4	0	0	0	112	L166 I167 L172 F174	L166-W170 WeakPolarHBondContact O-CB 3.33Å; L166-W170 PolarHBondContact O-N 3.39Å; I167-W170 PolarHBondContact O-N 2.89Å; W170-L172 PolarHBondContact O-N 2.83Å; W170-F174 HydrophobicContact CG-CB 4.34Å; W170-F174 WeakPolarHBondContact O-CA 3.15Å; W170-F174 WeakPolarHBondContact O-CB 3.5Å; W170-F174 PolarHBondContact O-N 3.4Å
171	A	79.7	Confident	75.5	Confident	46 Å²	46	84.3 Å²	84.3	38%	0.38	40%	0.4	S	S	.	.	I	π-helix	trans	-63.2	-34.5	-179.2	0	0	0	0	0	114.1	I167 G168 R175	I167-A171 WeakPolarHBondContact O-CB 3.26Å; I167-A171 PolarHBondContact O-N 3.4Å; G168-A171 PolarHBondContact O-N 3.44Å; A171-R175 WeakPolarHBondContact O-CB 3.25Å
172	L	72.3	Confident	73.6	Confident	20 Å²	20	88 Å²	88	11%	0.105	43%	0.428	C	S	.	.	I	π-helix	trans	-85.9	-37.8	179.7	-70.6	-173.7	0	0	0	114.4	G168 T169 W170 H236 A239 I240 E244	G168-L172 PolarHBondContact O-N 3.04Å; T169-L172 PolarHBondContact O-N 3.47Å; W170-L172 PolarHBondContact O-N 2.83Å; L172-H236 WeakPolarHBondContact CD1-CE1 3.46Å; L172-A239 HydrophobicContact CD1-CB 4.07Å; L172-I240 HydrophobicContact CD1-CG1 4.15Å; L172-I240 HydrophobicContact CD2-CG1 4.49Å; L172-E244 HydrophobicContact CD2-CG 4.31Å
173	F	67.7	Low	72.2	Confident	60 Å²	60	94 Å²	94	26%	0.263	45%	0.449	S	S	.	.	I	π-helix	trans	-106.6	-31.8	-169.6	-66.9	-82.6	0	0	0	114.3	T169 L192	T169-F173 WeakPolarHBondContact O-CB 3.42Å; T169-F173 WeakPolarHBondContact O-CD2 3.41Å; T169-F173 PolarHBondContact O-N 2.87Å; F173-L192 HydrophobicContact CE1-CD2 4.4Å
174	F	65.1	Low	70.8	Confident	139 Å²	139	94.4 Å²	94.4	61%	0.61	46%	0.455	S	S	*	.	I	π-helix	trans	-94.5	-3.7	-179.7	-72.4	-94.3	0	0	0	113.7	W170 K176	W170-F174 HydrophobicContact CG-CB 4.34Å; W170-F174 WeakPolarHBondContact O-CA 3.15Å; W170-F174 WeakPolarHBondContact O-CB 3.5Å; W170-F174 PolarHBondContact O-N 3.4Å; F174-K176 PolarHBondContact O-N 3.09Å; F174-K176 VanDerWaalsContact O-N 3.15Å
175	R	67.2	Low	69.7	Low	163 Å²	163	93 Å²	93	62%	0.615	45%	0.446	S	S	*	.	S	Bend	trans	-62.4	114.5	171.1	-172.9	177.5	-172.2	-170	3.9	110	A171 Q177	A171-R175 WeakPolarHBondContact O-CB 3.25Å; R175-Q177 PolarHBondContact O-N 3.2Å
176	K	55.5	Low	69	Low	186 Å²	186	96.9 Å²	96.9	81%	0.809	47%	0.47	S	S	*	.			trans	-46.5	112.7	-179	-174.3	175.1	-177.3	177.7	0	110.9	F174 R178	F174-K176 PolarHBondContact O-N 3.09Å; F174-K176 VanDerWaalsContact O-N 3.15Å; K176-R178 PolarHBondContact O-N 2.91Å
177	Q	56.2	Low	68.4	Low	115 Å²	115	96.5 Å²	96.5	54%	0.537	47%	0.465	S	S	.	.			trans	-66.2	125.9	173.4	-59.3	-164.6	-104	0	0	108.1	R175	R175-Q177 PolarHBondContact O-N 3.2Å
178	R	54.9	Low	68	Low	220 Å²	220	94.8 Å²	94.8	83%	0.83	45%	0.452	S	S	*	.	S	Bend	trans	-81.1	-17.4	-173.9	-68.2	-177.8	176.1	179.7	-4	113.8	K176	K176-R178 PolarHBondContact O-N 2.91Å
179	A	58.6	Low	67.9	Low	32 Å²	32	96 Å²	96	26%	0.264	46%	0.461	S	S	.	.	S	Bend	trans	-145.6	142.5	175.9	0	0	0	0	0	109.7	L279	A179-L279 HydrophobicContact CB-CD1 3.91Å; A179-L279 HydrophobicContact CB-CD2 3.84Å; A179-L279 HydrophobicContact CB-CG 4.4Å
180	D	54.7	Low	68.1	Low	101 Å²	101	99.3 Å²	99.3	54%	0.54	48%	0.477	S	S	.	.			trans	-80	132.6	175.1	-71.7	-70.5	0	0	0	111.2	R111	R111-D180 IonicContact CZ-OD1 2.85Å; R111-D180 IonicContact CZ-OD2 3.05Å; R111-D180 IonicContact NE-OD1 3.34Å; R111-D180 PolarHBondContact NE-OD1 3.28Å; R111-D180 IonicContact NE-OD2 2.66Å; R111-D180 IonicContact NH2-OD1 2.69Å; R111-D180 PolarHBondContact NH2-OD1 3.35Å; R111-D180 IonicContact NH2-OD2 3.77Å; R111-D180 PolarHBondContact NH2-OD2 2.89Å
181	V	59.3	Low	68.2	Low	55 Å²	55	91.3 Å²	91.3	33%	0.333	45%	0.447	S	S	.	.			trans	-109.1	122.2	173.4	-79	0	0	0	0	109.1	R183 Q275 L279	V181-R183 PolarHBondContact O-N 3.19Å; V181-Q275 HydrophobicContact CG1-CG 4.21Å; V181-L279 HydrophobicContact CG1-CD1 3.45Å; V181-L279 VanDerWaalsContact CG1-CD1 3.45Å
182	P	56.1	Low	68.5	Low	117 Å²	117	90.8 Å²	90.8	76%	0.76	44%	0.437	S	S	*	.	S	Bend	trans	-66.3	6.4	179.9	23.7	-36.3	0	0	0	115.4	Q275	P182-Q275 VanDerWaalsContact CD-NE2 3.31Å
183	R	63.4	Low	69.4	Low	140 Å²	140	93.9 Å²	93.9	53%	0.528	46%	0.457	S	S	.	.	S	Bend	trans	-142.2	140.2	-178.2	-64.3	-172.7	-179.6	-171	1	111.4	V181	V181-R183 PolarHBondContact O-N 3.19Å
184	V	62.8	Low	70.5	Confident	101 Å²	101	93.4 Å²	93.4	61%	0.612	46%	0.457	S	S	*	.			trans	-68.1	134.1	176.8	-174.6	0	0	0	0	109.9	V186 A189	V184-V186 PolarHBondContact O-N 3.45Å; V184-A189 HydrophobicContact CG1-CB 4.04Å
185	F	69.9	Low	71.8	Confident	53 Å²	53	88 Å²	88	23%	0.232	43%	0.434	C	S	.	.			trans	-69.3	122.6	177.9	-171.6	-118.9	0	0	0	110.7	F187 R188 A189 L243	F185-F187 VanDerWaalsContact C-N 3.31Å; F185-F187 HydrophobicContact CD1-CB 3.98Å; F185-F187 HydrophobicContact CD1-CD2 4.4Å; F185-F187 HydrophobicContact CE1-CB 3.71Å; F185-F187 AromaticContact CE1-CD2 3.65Å; F185-F187 HydrophobicContact CE1-CD2 3.65Å; F185-F187 HydrophobicContact CE1-CG 4.13Å; F185-F187 HydrophobicContact CE2-CD2 4.33Å; F185-F187 AromaticContact CZ-CD2 3.61Å; F185-F187 HydrophobicContact CZ-CD2 3.61Å; F185-F187 HydrophobicContact CZ-CE2 4.36Å; F185-F187 PolarHBondContact O-N 3.14Å; F185-R188 HydrophobicContact CB-CB 4.29Å; F185-R188 HydrophobicContact CB-CG 4.44Å; F185-R188 HydrophobicContact CD1-CB 4.46Å; F185-R188 HydrophobicContact CD1-CG 4.14Å; F185-R188 WeakPolarHBondContact O-CA 3.28Å; F185-R188 WeakPolarHBondContact O-CB 3.44Å; F185-R188 PolarHBondContact O-N 3.47Å; F185-A189 PolarHBondContact O-N 3.01Å; F185-L243 HydrophobicContact CD1-CD2 3.83Å; F185-L243 HydrophobicContact CE1-CD2 3.58Å
186	V	76.3	Confident	72.9	Confident	89 Å²	89	85.6 Å²	85.6	54%	0.539	43%	0.428	S	S	.	.	H	α-helix	trans	-54.1	-42.9	-171.3	-178.2	0	0	0	0	112.6	V184 R188 A189 L190	V184-V186 PolarHBondContact O-N 3.45Å; V186-R188 PolarHBondContact O-N 3.35Å; V186-A189 PolarHBondContact O-N 2.91Å; V186-L190 WeakPolarHBondContact O-CB 3.33Å; V186-L190 PolarHBondContact O-N 3.37Å
187	F	76.8	Confident	74.7	Confident	72 Å²	72	81.6 Å²	81.6	32%	0.316	42%	0.416	S	S	.	.	H	α-helix	trans	-67	-34.8	177.3	-62.7	-82.4	0	0	0	113	F185 L191 L242 L243	F185-F187 VanDerWaalsContact C-N 3.31Å; F185-F187 HydrophobicContact CD1-CB 3.98Å; F185-F187 HydrophobicContact CD1-CD2 4.4Å; F185-F187 HydrophobicContact CE1-CB 3.71Å; F185-F187 AromaticContact CE1-CD2 3.65Å; F185-F187 HydrophobicContact CE1-CD2 3.65Å; F185-F187 HydrophobicContact CE1-CG 4.13Å; F185-F187 HydrophobicContact CE2-CD2 4.33Å; F185-F187 AromaticContact CZ-CD2 3.61Å; F185-F187 HydrophobicContact CZ-CD2 3.61Å; F185-F187 HydrophobicContact CZ-CE2 4.36Å; F185-F187 PolarHBondContact O-N 3.14Å; F187-L191 WeakPolarHBondContact O-CB 3.14Å; F187-L191 WeakPolarHBondContact O-CD1 3.39Å; F187-L191 WeakPolarHBondContact O-CG 3.31Å; F187-L191 PolarHBondContact O-N 3.23Å; F187-L242 HydrophobicContact CD1-CD1 4.39Å; F187-L243 HydrophobicContact CB-CD2 4.18Å
188	R	80.8	Confident	76.5	Confident	66 Å²	66	79.6 Å²	79.6	25%	0.249	41%	0.405	C	S	.	.	H	α-helix	trans	-66.5	-42.9	173.1	-80.2	178.4	178.8	-174.9	-3.5	110.7	F185 V186 L191 L192 L243	F185-R188 HydrophobicContact CB-CB 4.29Å; F185-R188 HydrophobicContact CB-CG 4.44Å; F185-R188 HydrophobicContact CD1-CB 4.46Å; F185-R188 HydrophobicContact CD1-CG 4.14Å; F185-R188 WeakPolarHBondContact O-CA 3.28Å; F185-R188 WeakPolarHBondContact O-CB 3.44Å; F185-R188 PolarHBondContact O-N 3.47Å; V186-R188 PolarHBondContact O-N 3.35Å; R188-L191 PolarHBondContact O-N 3Å; R188-L192 VanDerWaalsContact O-CG 3.28Å; R188-L192 WeakPolarHBondContact O-CG 3.44Å; R188-L192 PolarHBondContact O-N 3.32Å; R188-L243 HydrophobicContact CG-CD1 3.97Å; R188-L243 HydrophobicContact CG-CD2 3.95Å
189	A	82.6	Confident	78.3	Confident	38 Å²	38	69.4 Å²	69.4	31%	0.314	37%	0.367	S	S	.	.	H	α-helix	trans	-61.2	-46.1	175.4	0	0	0	0	0	111.9	V184 F185 V186 L191 L192 V193	V184-A189 HydrophobicContact CG1-CB 4.04Å; F185-A189 PolarHBondContact O-N 3.01Å; V186-A189 PolarHBondContact O-N 2.91Å; A189-L191 PolarHBondContact O-N 2.83Å; A189-L192 PolarHBondContact O-N 3.48Å; A189-V193 WeakPolarHBondContact O-CG2 3.37Å; A189-V193 PolarHBondContact O-N 3.5Å
190	L	85.6	Confident	80	Confident	100 Å²	100	70.6 Å²	70.6	52%	0.524	37%	0.371	S	S	.	.	H	α-helix	trans	-60.8	-43.4	176.7	-174.4	153.7	0	0	0	111.8	V186 V193 L194	V186-L190 WeakPolarHBondContact O-CB 3.33Å; V186-L190 PolarHBondContact O-N 3.37Å; L190-V193 PolarHBondContact O-N 3.35Å; L190-L194 WeakPolarHBondContact O-CB 3.48Å; L190-L194 PolarHBondContact O-N 3.34Å
191	L	86.7	Confident	81.9	Confident	5 Å²	5	68.6 Å²	68.6	3%	0.026	37%	0.365	C	S	.	.	H	α-helix	trans	-63.8	-42	175.8	-72.9	163.2	0	0	0	112	F187 R188 A189 L194 I195 I235 A239 L243	F187-L191 WeakPolarHBondContact O-CB 3.14Å; F187-L191 WeakPolarHBondContact O-CD1 3.39Å; F187-L191 WeakPolarHBondContact O-CG 3.31Å; F187-L191 PolarHBondContact O-N 3.23Å; R188-L191 PolarHBondContact O-N 3Å; A189-L191 PolarHBondContact O-N 2.83Å; L191-L194 PolarHBondContact O-N 3.49Å; L191-I195 WeakPolarHBondContact O-CB 3.37Å; L191-I195 WeakPolarHBondContact O-CD1 3.33Å; L191-I195 WeakPolarHBondContact O-CG1 3.47Å; L191-I195 PolarHBondContact O-N 3.21Å; L191-I235 HydrophobicContact CD2-CG2 4.15Å; L191-A239 HydrophobicContact CD1-CB 3.65Å; L191-A239 HydrophobicContact CD2-CB 4.22Å; L191-L243 HydrophobicContact CD1-CD1 4.2Å; L191-L243 HydrophobicContact CD1-CD2 4.42Å; L191-L243 HydrophobicContact CD1-CG 4.24Å
192	L	87	Confident	83.5	Confident	34 Å²	34	68 Å²	68	18%	0.178	36%	0.357	C	S	.	.	H	α-helix	trans	-64.1	-41.7	175.6	-69.4	169.2	0	0	0	111.8	A118 L121 F173 R188 A189 I195 F196	A118-L192 HydrophobicContact CB-CD1 4.28Å; A118-L192 HydrophobicContact CB-CD2 4.35Å; L121-L192 HydrophobicContact CD2-CB 4.15Å; L121-L192 HydrophobicContact CD2-CD2 3.84Å; L121-L192 VanDerWaalsContact CD2-O 3.3Å; L121-L192 WeakPolarHBondContact CD2-O 3.34Å; F173-L192 HydrophobicContact CE1-CD2 4.4Å; R188-L192 VanDerWaalsContact O-CG 3.28Å; R188-L192 WeakPolarHBondContact O-CG 3.44Å; R188-L192 PolarHBondContact O-N 3.32Å; A189-L192 PolarHBondContact O-N 3.48Å; L192-I195 PolarHBondContact O-N 3.25Å; L192-F196 WeakPolarHBondContact O-CB 3.48Å; L192-F196 PolarHBondContact O-N 3.21Å
193	V	89.9	Confident	85.4	Confident	86 Å²	86	67 Å²	67	52%	0.521	34%	0.338	S	S	.	.	H	α-helix	trans	-63.7	-43.3	174.5	171.1	0	0	0	0	111.2	A189 L190 F196 L197	A189-V193 WeakPolarHBondContact O-CG2 3.37Å; A189-V193 PolarHBondContact O-N 3.5Å; L190-V193 PolarHBondContact O-N 3.35Å; V193-F196 PolarHBondContact O-N 2.97Å; V193-L197 HydrophobicContact CG1-CD1 4.06Å; V193-L197 HydrophobicContact CG1-CG 4.42Å; V193-L197 WeakPolarHBondContact O-CG 3.35Å; V193-L197 PolarHBondContact O-N 2.98Å
194	L	91.3	Very high	86.8	Confident	50 Å²	50	66 Å²	66	26%	0.262	34%	0.343	S	S	.	.	H	α-helix	trans	-60.2	-48.4	176.5	-174.4	67.7	0	0	0	111.3	L190 L191 F196 L197 F198 I235	L190-L194 WeakPolarHBondContact O-CB 3.48Å; L190-L194 PolarHBondContact O-N 3.34Å; L191-L194 PolarHBondContact O-N 3.49Å; L194-F196 VanDerWaalsContact C-N 3.34Å; L194-F196 PolarHBondContact O-N 2.86Å; L194-L197 PolarHBondContact O-N 3.01Å; L194-F198 HydrophobicContact CD1-CD2 3.99Å; L194-F198 HydrophobicContact CD1-CE2 3.75Å; L194-F198 HydrophobicContact CG-CD2 4.2Å; L194-F198 HydrophobicContact CG-CE2 4.25Å; L194-F198 WeakPolarHBondContact O-CD2 3.31Å; L194-F198 PolarHBondContact O-N 2.61Å; L194-I235 HydrophobicContact CD2-CD1 4.35Å; L194-I235 HydrophobicContact CD2-CG1 4.1Å; L194-I235 HydrophobicContact CD2-CG2 4.25Å; L194-I235 HydrophobicContact CG-CD1 4.28Å
195	I	91.6	Very high	88.3	Confident	25 Å²	25	66.2 Å²	66.2	13%	0.128	34%	0.336	C	S	.	.	H	α-helix	trans	-57.1	-47.4	175.4	-72.2	167.2	0	0	0	110.8	L121 V125 L191 L192 F198 V199 I235	L121-I195 HydrophobicContact CD1-CG2 4.38Å; L121-I195 HydrophobicContact CD2-CB 4.18Å; L121-I195 HydrophobicContact CD2-CG2 3.82Å; L121-I195 HydrophobicContact CG-CG2 3.96Å; V125-I195 HydrophobicContact CG2-CG2 3.29Å; L191-I195 WeakPolarHBondContact O-CB 3.37Å; L191-I195 WeakPolarHBondContact O-CD1 3.33Å; L191-I195 WeakPolarHBondContact O-CG1 3.47Å; L191-I195 PolarHBondContact O-N 3.21Å; L192-I195 PolarHBondContact O-N 3.25Å; I195-F198 PolarHBondContact O-N 3.21Å; I195-V199 HydrophobicContact CG2-CG2 4.38Å; I195-V199 WeakPolarHBondContact O-CB 3.23Å; I195-V199 WeakPolarHBondContact O-CG2 3.44Å; I195-V199 PolarHBondContact O-N 2.77Å; I195-I235 HydrophobicContact CD1-CG2 4.17Å; I195-I235 HydrophobicContact CG1-CG2 3.72Å
196	F	92.1	Very high	89.4	Confident	112 Å²	112	63.7 Å²	63.7	49%	0.491	33%	0.325	S	S	.	.	H	α-helix	trans	-60.3	-46.7	178.8	175.6	-99.6	0	0	0	112.3	L121 L192 V193 L194 F198 V199 V200	L121-F196 HydrophobicContact CD1-CB 4.16Å; L121-F196 HydrophobicContact CD1-CD2 4.13Å; L121-F196 HydrophobicContact CD2-CB 4.31Å; L192-F196 WeakPolarHBondContact O-CB 3.48Å; L192-F196 PolarHBondContact O-N 3.21Å; V193-F196 PolarHBondContact O-N 2.97Å; L194-F196 VanDerWaalsContact C-N 3.34Å; L194-F196 PolarHBondContact O-N 2.86Å; F196-F198 PolarHBondContact O-N 3.4Å; F196-V199 PolarHBondContact O-N 3.42Å; F196-V200 HydrophobicContact CD1-CG2 4.46Å; F196-V200 HydrophobicContact CD2-CG2 4.21Å; F196-V200 HydrophobicContact CE1-CG2 4.08Å; F196-V200 HydrophobicContact CE2-CG2 3.8Å; F196-V200 HydrophobicContact CZ-CG2 3.74Å; F196-V200 WeakPolarHBondContact O-CB 3.42Å; F196-V200 WeakPolarHBondContact O-CG2 3.19Å; F196-V200 PolarHBondContact O-N 3.33Å
197	L	93.3	Very high	90.1	Very high	103 Å²	103	60.7 Å²	60.7	54%	0.539	31%	0.312	S	S	.	.	H	α-helix	trans	-61.9	-41.7	178.1	-70.5	173.5	0	0	0	112.2	V193 L194 S201	V193-L197 HydrophobicContact CG1-CD1 4.06Å; V193-L197 HydrophobicContact CG1-CG 4.42Å; V193-L197 WeakPolarHBondContact O-CG 3.35Å; V193-L197 PolarHBondContact O-N 2.98Å; L194-L197 PolarHBondContact O-N 3.01Å; L197-S201 WeakPolarHBondContact O-CB 3.42Å; L197-S201 PolarHBondContact O-N 2.88Å; L197-S201 PolarHBondContact O-OG 3.3Å
198	F	92.6	Very high	90.8	Very high	72 Å²	72	61.7 Å²	61.7	32%	0.316	32%	0.324	S	S	.	.	H	α-helix	trans	-64.5	-46.9	174.5	-92.7	-101.8	0	0	0	111.9	L194 I195 F196 V200 S201 Y202 A231 I235	L194-F198 HydrophobicContact CD1-CD2 3.99Å; L194-F198 HydrophobicContact CD1-CE2 3.75Å; L194-F198 HydrophobicContact CG-CD2 4.2Å; L194-F198 HydrophobicContact CG-CE2 4.25Å; L194-F198 WeakPolarHBondContact O-CD2 3.31Å; L194-F198 PolarHBondContact O-N 2.61Å; I195-F198 PolarHBondContact O-N 3.21Å; F196-F198 PolarHBondContact O-N 3.4Å; F198-V200 VanDerWaalsContact C-N 3.34Å; F198-V200 PolarHBondContact O-N 3.36Å; F198-S201 PolarHBondContact O-N 3.43Å; F198-S201 PolarHBondContact O-OG 3.46Å; F198-S201 VanDerWaalsContact O-OG 3.05Å; F198-Y202 HydrophobicContact CD1-CD2 4.47Å; F198-Y202 HydrophobicContact CD1-CE2 4.01Å; F198-Y202 WeakPolarHBondContact O-CB 3.47Å; F198-Y202 VanDerWaalsContact O-CD2 3.29Å; F198-Y202 WeakPolarHBondContact O-CD2 3.41Å; F198-Y202 PolarHBondContact O-N 2.89Å; F198-A231 HydrophobicContact CD1-CB 4.16Å; F198-A231 HydrophobicContact CE1-CB 4.17Å; F198-I235 HydrophobicContact CB-CD1 4.42Å; F198-I235 HydrophobicContact CD1-CD1 4.33Å; F198-I235 HydrophobicContact CD2-CD1 4.03Å; F198-I235 HydrophobicContact CE2-CD1 4.38Å; F198-I235 HydrophobicContact CG-CD1 4Å
199	V	92.8	Very high	91.2	Very high	7 Å²	7	65.9 Å²	65.9	4%	0.042	34%	0.34	C	S	.	.	H	α-helix	trans	-61.1	-43.7	179.4	168.4	0	0	0	0	111.2	V125 T128 I195 F196 W203 L232	V125-V199 HydrophobicContact CG2-CG2 3.96Å; T128-V199 HydrophobicContact CG2-CG1 3.95Å; I195-V199 HydrophobicContact CG2-CG2 4.38Å; I195-V199 WeakPolarHBondContact O-CB 3.23Å; I195-V199 WeakPolarHBondContact O-CG2 3.44Å; I195-V199 PolarHBondContact O-N 2.77Å; F196-V199 PolarHBondContact O-N 3.42Å; V199-W203 VanDerWaalsContact O-CD1 3.31Å; V199-W203 PolarHBondContact O-N 2.99Å; V199-L232 HydrophobicContact CG2-CD2 4.47Å
200	V	94	Very high	91.4	Very high	56 Å²	56	64.5 Å²	64.5	34%	0.339	33%	0.327	S	S	.	.	H	α-helix	trans	-67.5	-43.6	178.6	172.7	0	0	0	0	111.8	F196 F198 Y202 W203 L204	F196-V200 HydrophobicContact CD1-CG2 4.46Å; F196-V200 HydrophobicContact CD2-CG2 4.21Å; F196-V200 HydrophobicContact CE1-CG2 4.08Å; F196-V200 HydrophobicContact CE2-CG2 3.8Å; F196-V200 HydrophobicContact CZ-CG2 3.74Å; F196-V200 WeakPolarHBondContact O-CB 3.42Å; F196-V200 WeakPolarHBondContact O-CG2 3.19Å; F196-V200 PolarHBondContact O-N 3.33Å; F198-V200 VanDerWaalsContact C-N 3.34Å; F198-V200 PolarHBondContact O-N 3.36Å; V200-Y202 VanDerWaalsContact C-N 3.34Å; V200-Y202 PolarHBondContact O-N 2.89Å; V200-W203 PolarHBondContact O-N 2.8Å; V200-L204 HydrophobicContact CG1-CD1 4.02Å; V200-L204 HydrophobicContact CG1-CG 4.39Å; V200-L204 WeakPolarHBondContact O-CG 3.41Å; V200-L204 PolarHBondContact O-N 2.88Å
201	S	94.3	Very high	91.5	Very high	60 Å²	60	62.1 Å²	62.1	42%	0.42	31%	0.314	S	S	.	.	H	α-helix	trans	-64.7	-38.9	179.9	67.2	0	0	0	0	112.3	L197 F198 L204 F205	L197-S201 WeakPolarHBondContact O-CB 3.42Å; L197-S201 PolarHBondContact O-N 2.88Å; L197-S201 PolarHBondContact O-OG 3.3Å; F198-S201 PolarHBondContact O-N 3.43Å; F198-S201 PolarHBondContact O-OG 3.46Å; F198-S201 VanDerWaalsContact O-OG 3.05Å; S201-L204 PolarHBondContact O-N 2.82Å; S201-F205 PolarHBondContact O-N 3Å; S201-F205 VanDerWaalsContact O-N 3.1Å
202	Y	94.8	Very high	91.5	Very high	43 Å²	43	68.3 Å²	68.3	17%	0.169	35%	0.347	C	S	.	.	H	α-helix	trans	-66.5	-39.6	173.9	-89	-102	0	0	0	112.5	F198 V200 Y206 Y224 L228	F198-Y202 HydrophobicContact CD1-CD2 4.47Å; F198-Y202 HydrophobicContact CD1-CE2 4.01Å; F198-Y202 WeakPolarHBondContact O-CB 3.47Å; F198-Y202 VanDerWaalsContact O-CD2 3.29Å; F198-Y202 WeakPolarHBondContact O-CD2 3.41Å; F198-Y202 PolarHBondContact O-N 2.89Å; V200-Y202 VanDerWaalsContact C-N 3.34Å; V200-Y202 PolarHBondContact O-N 2.89Å; Y202-Y206 WeakPolarHBondContact O-CB 3.31Å; Y202-Y206 PolarHBondContact O-N 3.41Å; Y202-Y224 WeakPolarHBondContact CA-OH 3.18Å; Y202-Y224 AromaticContact CD1-CE1 3.87Å; Y202-Y224 HydrophobicContact CD1-CE1 3.87Å; Y202-Y224 HydrophobicContact CD1-CE2 4.02Å; Y202-Y224 AromaticContact CD1-CZ 3.45Å; Y202-Y224 VanDerWaalsContact CD1-CZ 3.45Å; Y202-Y224 WeakPolarHBondContact CD1-OH 3.4Å; Y202-Y224 HydrophobicContact CE1-CE2 4.05Å; Y202-Y224 AromaticContact CE1-CZ 3.96Å; Y202-Y224 PolarHBondContact O-OH 2.67Å; Y202-Y224 VanDerWaalsContact O-OH 3.06Å; Y202-L228 HydrophobicContact CD1-CB 3.68Å; Y202-L228 HydrophobicContact CD1-CD1 3.96Å; Y202-L228 HydrophobicContact CD1-CD2 4.49Å; Y202-L228 HydrophobicContact CD1-CG 4.24Å; Y202-L228 HydrophobicContact CD2-CD1 4.05Å; Y202-L228 HydrophobicContact CE1-CB 3.71Å; Y202-L228 HydrophobicContact CE1-CD1 4.36Å; Y202-L228 HydrophobicContact CE2-CD1 4.44Å; Y202-L228 HydrophobicContact CG-CB 4.39Å; Y202-L228 HydrophobicContact CG-CD1 3.78Å; Y202-L228 HydrophobicContact CG-CG 4.49Å
203	W	94.8	Very high	91.4	Very high	94 Å²	94	70.3 Å²	70.3	36%	0.356	36%	0.364	S	S	.	.	H	α-helix	trans	-62.5	-43.6	173.4	-95	109.3	0	0	0	113.3	T128 A131 F132 V199 V200 Y206 G207	T128-W203 HydrophobicContact CG2-CZ2 4.22Å; A131-W203 HydrophobicContact CB-CH2 4.33Å; A131-W203 HydrophobicContact CB-CZ2 4.33Å; F132-W203 HydrophobicContact CD1-CH2 4.42Å; F132-W203 HydrophobicContact CD1-CZ2 4.49Å; F132-W203 AromaticContact CE1-CD2 3.67Å; F132-W203 HydrophobicContact CE1-CD2 3.67Å; F132-W203 AromaticContact CE1-CE2 3.77Å; F132-W203 AromaticContact CE1-CE3 3.78Å; F132-W203 HydrophobicContact CE1-CE3 3.78Å; F132-W203 HydrophobicContact CE1-CG 4.23Å; F132-W203 HydrophobicContact CE1-CH2 4.07Å; F132-W203 AromaticContact CE1-CZ2 3.97Å; F132-W203 HydrophobicContact CE1-CZ2 3.97Å; F132-W203 AromaticContact CE1-CZ3 3.98Å; F132-W203 HydrophobicContact CE1-CZ3 3.98Å; F132-W203 HydrophobicContact CZ-CD2 4.17Å; F132-W203 HydrophobicContact CZ-CG 4.25Å; V199-W203 VanDerWaalsContact O-CD1 3.31Å; V199-W203 PolarHBondContact O-N 2.99Å; V200-W203 PolarHBondContact O-N 2.8Å; W203-Y206 HydrophobicContact CE3-CD1 4.42Å; W203-Y206 HydrophobicContact CZ3-CD1 4.34Å; W203-Y206 PolarHBondContact O-N 2.88Å; W203-G207 PolarHBondContact O-N 3.24Å
204	L	93.8	Very high	91	Very high	121 Å²	121	72.6 Å²	72.6	63%	0.634	36%	0.363	S	S	*	.	H	α-helix	trans	-63	-45.3	179.2	-70.8	170.9	0	0	0	111.3	V200 S201 G207 V208	V200-L204 HydrophobicContact CG1-CD1 4.02Å; V200-L204 HydrophobicContact CG1-CG 4.39Å; V200-L204 WeakPolarHBondContact O-CG 3.41Å; V200-L204 PolarHBondContact O-N 2.88Å; S201-L204 PolarHBondContact O-N 2.82Å; L204-G207 PolarHBondContact O-N 3.4Å; L204-V208 WeakPolarHBondContact O-CG2 3.42Å; L204-V208 PolarHBondContact O-N 3.38Å; L204-V208 VanDerWaalsContact O-N 3.16Å
205	F	93.4	Very high	90.6	Very high	105 Å²	105	72.7 Å²	72.7	46%	0.461	36%	0.364	S	S	.	.	H	α-helix	trans	-67.3	-41.6	177.3	-172.5	-85	0	0	0	111.7	S201 G207 V208 R209 Y224	S201-F205 PolarHBondContact O-N 3Å; S201-F205 VanDerWaalsContact O-N 3.1Å; F205-G207 PolarHBondContact O-N 3.13Å; F205-V208 PolarHBondContact O-N 3.47Å; F205-R209 HydrophobicContact CD1-CB 4.13Å; F205-R209 HydrophobicContact CD1-CG 4.11Å; F205-R209 HydrophobicContact CD2-CG 4.18Å; F205-R209 HydrophobicContact CE1-CB 3.92Å; F205-R209 HydrophobicContact CE1-CG 3.82Å; F205-R209 HydrophobicContact CE2-CG 3.9Å; F205-R209 HydrophobicContact CG-CG 4.3Å; F205-R209 HydrophobicContact CZ-CB 4.31Å; F205-R209 HydrophobicContact CZ-CG 3.72Å; F205-R209 VanDerWaalsContact O-CB 3.27Å; F205-R209 WeakPolarHBondContact O-CB 3.32Å; F205-R209 PolarHBondContact O-N 3.4Å; F205-Y224 HydrophobicContact CD1-CD2 4.43Å; F205-Y224 AromaticContact CD1-CE2 3.54Å; F205-Y224 HydrophobicContact CD1-CE2 3.54Å; F205-Y224 AromaticContact CD1-CZ 3.62Å; F205-Y224 WeakPolarHBondContact CD1-OH 3.28Å; F205-Y224 HydrophobicContact CE1-CD2 4.36Å; F205-Y224 AromaticContact CE1-CE2 3.8Å; F205-Y224 HydrophobicContact CE1-CE2 3.8Å
206	Y	93.1	Very high	90.2	Very high	0 Å²	0	75.6 Å²	75.6	0%	0	38%	0.377	C	S	.	.	H	α-helix	trans	-58.1	-45.4	174.2	-176	-92.8	0	0	0	112.3	F132 L135 P136 Y202 W203 I210 L211 I221 Y224	F132-Y206 HydrophobicContact CB-CD2 4.12Å; F132-Y206 HydrophobicContact CB-CE2 3.65Å; F132-Y206 AromaticContact CD1-CD1 3.83Å; F132-Y206 HydrophobicContact CD1-CD1 3.83Å; F132-Y206 AromaticContact CD1-CD2 3.69Å; F132-Y206 HydrophobicContact CD1-CD2 3.69Å; F132-Y206 AromaticContact CD1-CE1 3.89Å; F132-Y206 HydrophobicContact CD1-CE1 3.89Å; F132-Y206 AromaticContact CD1-CE2 3.79Å; F132-Y206 HydrophobicContact CD1-CE2 3.79Å; F132-Y206 AromaticContact CD1-CG 3.74Å; F132-Y206 HydrophobicContact CD1-CG 3.74Å; F132-Y206 AromaticContact CD1-CZ 3.9Å; F132-Y206 AromaticContact CD2-CD2 3.77Å; F132-Y206 HydrophobicContact CD2-CD2 3.77Å; F132-Y206 HydrophobicContact CD2-CE2 4.21Å; F132-Y206 HydrophobicContact CD2-CG 4.32Å; F132-Y206 AromaticContact CE1-CD1 3.75Å; F132-Y206 HydrophobicContact CE1-CD1 3.75Å; F132-Y206 AromaticContact CE1-CD2 3.97Å; F132-Y206 HydrophobicContact CE1-CD2 3.97Å; F132-Y206 HydrophobicContact CE1-CE1 4.27Å; F132-Y206 HydrophobicContact CE1-CE2 4.49Å; F132-Y206 AromaticContact CE1-CG 3.6Å; F132-Y206 HydrophobicContact CE1-CG 3.6Å; F132-Y206 HydrophobicContact CE2-CD2 4.05Å; F132-Y206 HydrophobicContact CE2-CG 4.2Å; F132-Y206 AromaticContact CG-CD2 3.59Å; F132-Y206 HydrophobicContact CG-CD2 3.59Å; F132-Y206 AromaticContact CG-CE2 3.63Å; F132-Y206 HydrophobicContact CG-CE2 3.63Å; F132-Y206 HydrophobicContact CG-CG 4.11Å; F132-Y206 HydrophobicContact CZ-CD1 4.42Å; F132-Y206 HydrophobicContact CZ-CD2 4.15Å; F132-Y206 AromaticContact CZ-CG 3.85Å; F132-Y206 HydrophobicContact CZ-CG 3.85Å; F132-Y206 PolarHBondContact O-OH 2.84Å; F132-Y206 VanDerWaalsContact O-OH 3.1Å; L135-Y206 HydrophobicContact CD2-CE1 4.32Å; P136-Y206 VanDerWaalsContact CD-OH 3.26Å; P136-Y206 WeakPolarHBondContact CD-OH 3.4Å; P136-Y206 VanDerWaalsContact CG-OH 3.25Å; P136-Y206 WeakPolarHBondContact CG-OH 3.43Å; Y202-Y206 WeakPolarHBondContact O-CB 3.31Å; Y202-Y206 PolarHBondContact O-N 3.41Å; W203-Y206 HydrophobicContact CE3-CD1 4.42Å; W203-Y206 HydrophobicContact CZ3-CD1 4.34Å; W203-Y206 PolarHBondContact O-N 2.88Å; Y206-I210 HydrophobicContact CD2-CB 4.16Å; Y206-I210 HydrophobicContact CD2-CD1 3.44Å; Y206-I210 VanDerWaalsContact CD2-CD1 3.44Å; Y206-I210 HydrophobicContact CD2-CG1 4.37Å; Y206-I210 HydrophobicContact CD2-CG2 4.37Å; Y206-I210 HydrophobicContact CE2-CB 4.13Å; Y206-I210 HydrophobicContact CE2-CD1 3.75Å; Y206-I210 HydrophobicContact CE2-CG2 3.83Å; Y206-I210 HydrophobicContact CG-CD1 4.34Å; Y206-I210 WeakPolarHBondContact O-CA 3.15Å; Y206-I210 WeakPolarHBondContact O-CB 3.32Å; Y206-I210 PolarHBondContact O-N 3.34Å; Y206-L211 HydrophobicContact CD1-CD1 4.04Å; Y206-L211 HydrophobicContact CD1-CD2 4.47Å; Y206-L211 HydrophobicContact CD1-CG 3.98Å; Y206-L211 HydrophobicContact CE1-CD1 3.83Å; Y206-L211 HydrophobicContact CE1-CD2 3.68Å; Y206-L211 HydrophobicContact CE1-CG 3.67Å; Y206-L211 PolarHBondContact O-N 3Å; Y206-I221 HydrophobicContact CE2-CG2 4.36Å; Y206-Y224 HydrophobicContact CD2-CD1 4.04Å; Y206-Y224 HydrophobicContact CD2-CE1 4.03Å
207	G	90.6	Very high	90.1	Very high	26 Å²	26	72.8 Å²	72.8	27%	0.268	37%	0.368	S	S	.	.	I	π-helix	trans	-57.5	-51.8	176.4	0	0	0	0	0	112.6	W203 L204 F205 L211 D212	W203-G207 PolarHBondContact O-N 3.24Å; L204-G207 PolarHBondContact O-N 3.4Å; F205-G207 PolarHBondContact O-N 3.13Å; G207-L211 WeakPolarHBondContact O-CB 3.3Å; G207-L211 PolarHBondContact O-N 2.88Å; G207-D212 PolarHBondContact O-N 2.94Å
208	V	92.4	Very high	89.8	Confident	92 Å²	92	69.5 Å²	69.5	56%	0.558	35%	0.348	S	S	*	.	I	π-helix	trans	-74.9	-35	-176.3	178	0	0	0	0	113.2	L204 F205	L204-V208 WeakPolarHBondContact O-CG2 3.42Å; L204-V208 PolarHBondContact O-N 3.38Å; L204-V208 VanDerWaalsContact O-N 3.16Å; F205-V208 PolarHBondContact O-N 3.47Å
209	R	87.8	Confident	89.7	Confident	155 Å²	155	70.6 Å²	70.6	59%	0.585	35%	0.353	S	S	*	.	I	π-helix	trans	-100.8	-17.4	-171.5	-69.4	-66.6	-165.5	162.5	0	115.7	F205 S213	F205-R209 HydrophobicContact CD1-CB 4.13Å; F205-R209 HydrophobicContact CD1-CG 4.11Å; F205-R209 HydrophobicContact CD2-CG 4.18Å; F205-R209 HydrophobicContact CE1-CB 3.92Å; F205-R209 HydrophobicContact CE1-CG 3.82Å; F205-R209 HydrophobicContact CE2-CG 3.9Å; F205-R209 HydrophobicContact CG-CG 4.3Å; F205-R209 HydrophobicContact CZ-CB 4.31Å; F205-R209 HydrophobicContact CZ-CG 3.72Å; F205-R209 VanDerWaalsContact O-CB 3.27Å; F205-R209 WeakPolarHBondContact O-CB 3.32Å; F205-R209 PolarHBondContact O-N 3.4Å; R209-S213 PolarHBondContact O-OG 2.93Å
210	I	87.5	Confident	89.5	Confident	9 Å²	9	73.1 Å²	73.1	5%	0.046	37%	0.366	C	S	.	.	I	π-helix	trans	-120.3	-41.2	-177.6	-65.9	162.2	0	0	0	110.8	Y206 R214 D215 I221 Y224	Y206-I210 HydrophobicContact CD2-CB 4.16Å; Y206-I210 HydrophobicContact CD2-CD1 3.44Å; Y206-I210 VanDerWaalsContact CD2-CD1 3.44Å; Y206-I210 HydrophobicContact CD2-CG1 4.37Å; Y206-I210 HydrophobicContact CD2-CG2 4.37Å; Y206-I210 HydrophobicContact CE2-CB 4.13Å; Y206-I210 HydrophobicContact CE2-CD1 3.75Å; Y206-I210 HydrophobicContact CE2-CG2 3.83Å; Y206-I210 HydrophobicContact CG-CD1 4.34Å; Y206-I210 WeakPolarHBondContact O-CA 3.15Å; Y206-I210 WeakPolarHBondContact O-CB 3.32Å; Y206-I210 PolarHBondContact O-N 3.34Å; I210-R214 WeakPolarHBondContact O-CA 3.43Å; I210-R214 PolarHBondContact O-N 2.87Å; I210-D215 PolarHBondContact O-N 2.85Å; I210-I221 HydrophobicContact CG1-CG1 4.48Å; I210-I221 HydrophobicContact CG2-CD1 3.79Å; I210-I221 HydrophobicContact CG2-CG1 3.9Å; I210-I221 HydrophobicContact CG2-CG2 4.46Å; I210-Y224 HydrophobicContact CD1-CD1 3.84Å; I210-Y224 HydrophobicContact CD1-CE1 4.42Å; I210-Y224 HydrophobicContact CD1-CG 4.16Å
211	L	87	Confident	89.4	Confident	49 Å²	49	70.5 Å²	70.5	26%	0.257	35%	0.35	S	S	.	.	I	π-helix	trans	-83.4	-48.4	-179.6	-56.7	-176.1	0	0	0	113.5	L135 L139 Y206 G207	L135-L211 HydrophobicContact CD2-CD1 3.99Å; L135-L211 HydrophobicContact CD2-CD2 3.36Å; L135-L211 HydrophobicContact CD2-CG 4.33Å; L139-L211 HydrophobicContact CD1-CD2 4.4Å; Y206-L211 HydrophobicContact CD1-CD1 4.04Å; Y206-L211 HydrophobicContact CD1-CD2 4.47Å; Y206-L211 HydrophobicContact CD1-CG 3.98Å; Y206-L211 HydrophobicContact CE1-CD1 3.83Å; Y206-L211 HydrophobicContact CE1-CD2 3.68Å; Y206-L211 HydrophobicContact CE1-CG 3.67Å; Y206-L211 PolarHBondContact O-N 3Å; G207-L211 WeakPolarHBondContact O-CB 3.3Å; G207-L211 PolarHBondContact O-N 2.88Å
212	D	87.7	Confident	89.2	Confident	136 Å²	136	67.6 Å²	67.6	73%	0.727	33%	0.33	S	S	*	.	I	π-helix	trans	-69.1	-47	-178.2	-163.6	38.8	0	0	0	111.4	G207 R214	G207-D212 PolarHBondContact O-N 2.94Å; D212-R214 PolarHBondContact O-N 3.43Å
213	S	84.2	Confident	89.1	Confident	76 Å²	76	70.5 Å²	70.5	53%	0.531	35%	0.345	S	S	.	.	T	Hydrogen-bonded Turn	trans	-85.6	2.8	177.9	49.7	0	0	0	0	116	R209 D215	R209-S213 PolarHBondContact O-OG 2.93Å; S213-D215 PolarHBondContact O-N 3.14Å
214	R	82.7	Confident	89	Confident	133 Å²	133	67.8 Å²	67.8	50%	0.502	34%	0.335	S	S	.	.	T	Hydrogen-bonded Turn	trans	41.1	66.5	177.8	-60.4	-173	-174.8	-171.1	2.2	114.7	W140 E143 I210 D212 Q216	W140-R214 HydrophobicContact CZ2-CB 4.4Å; E143-R214 IonicContact OE1-NH1 3.51Å; E143-R214 IonicContact OE2-NH1 3.88Å; I210-R214 WeakPolarHBondContact O-CA 3.43Å; I210-R214 PolarHBondContact O-N 2.87Å; D212-R214 PolarHBondContact O-N 3.43Å; R214-Q216 PolarHBondContact O-N 2.9Å
215	D	81.6	Confident	89	Confident	52 Å²	52	62 Å²	62	28%	0.278	31%	0.305	S	S	.	.			trans	-69.6	105.2	-174.1	-168.9	-11.4	0	0	0	113.1	W140 I210 S213 N217	W140-D215 WeakPolarHBondContact CH2-O 3.43Å; W140-D215 VanDerWaalsContact CZ3-O 3.27Å; W140-D215 WeakPolarHBondContact CZ3-O 3.05Å; I210-D215 PolarHBondContact O-N 2.85Å; S213-D215 PolarHBondContact O-N 3.14Å; D215-N217 PolarHBondContact O-N 3.33Å; D215-N217 VanDerWaalsContact O-N 3.09Å; D215-N217 WeakPolarHBondContact OD1-CB 3.49Å; D215-N217 PolarHBondContact OD1-N 3.42Å
216	Q	84.6	Confident	89.1	Confident	86 Å²	86	57.5 Å²	57.5	40%	0.402	29%	0.286	S	S	.	.			trans	-65.8	-11.3	-177.7	-61.8	-172.3	-16.2	0	0	114.6	E143 K145 R214 Y218	E143-Q216 WeakPolarHBondContact O-CB 3.46Å; E143-Q216 VanDerWaalsContact O-CG 3.23Å; E143-Q216 WeakPolarHBondContact O-CG 3.17Å; K145-Q216 PolarHBondContact N-O 2.99Å; K145-Q216 VanDerWaalsContact N-O 3.11Å; R214-Q216 PolarHBondContact O-N 2.9Å; Q216-Y218 PolarHBondContact O-N 3.48Å
217	N	88.4	Confident	89.2	Confident	54 Å²	54	59.6 Å²	59.6	29%	0.289	30%	0.3	S	S	.	.			trans	-84.3	85.7	178.5	-69.5	-9	0	0	0	111.8	K145 D215 K219 D220 I221	K145-N217 PolarHBondContact NZ-OD1 3.23Å; D215-N217 PolarHBondContact O-N 3.33Å; D215-N217 VanDerWaalsContact O-N 3.09Å; D215-N217 WeakPolarHBondContact OD1-CB 3.49Å; D215-N217 PolarHBondContact OD1-N 3.42Å; N217-K219 PolarHBondContact O-N 2.9Å; N217-D220 HydrophobicContact CB-CB 4.13Å; N217-D220 WeakPolarHBondContact CB-OD2 3.41Å; N217-D220 PolarHBondContact ND2-OD2 2.89Å; N217-D220 PolarHBondContact O-N 3.38Å; N217-I221 PolarHBondContact O-N 2.92Å
218	Y	88.3	Confident	89.3	Confident	33 Å²	33	58.4 Å²	58.4	13%	0.129	29%	0.288	C	S	.	.	H	α-helix	trans	-54.1	-31.2	178.6	-173.2	-112.8	0	0	0	114.4	I133 L144 C147 C151 L155 Q216 D220 I221 V222	I133-Y218 VanDerWaalsContact CG2-OH 3.31Å; I133-Y218 WeakPolarHBondContact CG2-OH 3.46Å; L144-Y218 HydrophobicContact CD2-CD2 3.91Å; L144-Y218 HydrophobicContact CD2-CG 4.3Å; C147-Y218 HydrophobicContact CB-CD1 3.85Å; C147-Y218 HydrophobicContact CB-CE1 4.13Å; C151-Y218 VanDerWaalsContact SG-CD1 3.59Å; L155-Y218 HydrophobicContact CD1-CE1 4.4Å; Q216-Y218 PolarHBondContact O-N 3.48Å; Y218-D220 VanDerWaalsContact C-N 3.31Å; Y218-D220 PolarHBondContact O-N 3.41Å; Y218-I221 PolarHBondContact O-N 2.84Å; Y218-V222 HydrophobicContact CD1-CG2 4.01Å; Y218-V222 HydrophobicContact CD2-CG2 4.46Å; Y218-V222 HydrophobicContact CE1-CG2 3.61Å; Y218-V222 HydrophobicContact CE2-CG2 4.11Å; Y218-V222 HydrophobicContact CG-CG2 4.43Å; Y218-V222 WeakPolarHBondContact O-CG2 3.31Å; Y218-V222 PolarHBondContact O-N 3.42Å
219	K	89.7	Confident	89.5	Confident	95 Å²	95	54 Å²	54	41%	0.413	26%	0.261	S	S	.	.	H	α-helix	trans	-56.6	-44	173.1	-178.1	-161.7	167.1	-157.6	0	112.2	C151 N217 V222 Q223	C151-K219 HydrophobicContact CB-CB 4.31Å; C151-K219 HydrophobicContact CB-CG 4.34Å; N217-K219 PolarHBondContact O-N 2.9Å; K219-V222 PolarHBondContact O-N 3.13Å; K219-Q223 WeakPolarHBondContact O-CB 3.49Å; K219-Q223 PolarHBondContact O-N 2.8Å
220	D	89.3	Confident	89.8	Confident	61 Å²	61	48.8 Å²	48.8	33%	0.326	25%	0.245	S	C	.	.	H	α-helix	trans	-74.2	-34.6	-173.3	-59.2	-25.9	0	0	0	110.1	N217 Y218 Q223 Y224	N217-D220 HydrophobicContact CB-CB 4.13Å; N217-D220 WeakPolarHBondContact CB-OD2 3.41Å; N217-D220 PolarHBondContact ND2-OD2 2.89Å; N217-D220 PolarHBondContact O-N 3.38Å; Y218-D220 VanDerWaalsContact C-N 3.31Å; Y218-D220 PolarHBondContact O-N 3.41Å; D220-Q223 PolarHBondContact O-N 3.32Å; D220-Y224 WeakPolarHBondContact O-CB 3.46Å; D220-Y224 PolarHBondContact O-N 3.35Å
221	I	90.8	Very high	90.1	Very high	0 Å²	0	49.2 Å²	49.2	0%	0	25%	0.25	C	C	.	.	H	α-helix	trans	-60.2	-51.1	168.5	-57.4	179.9	0	0	0	111.4	F132 P136 W140 L144 Y206 I210 N217 Y218 Q223 Y224 A225	F132-I221 WeakPolarHBondContact O-CG2 3.5Å; P136-I221 HydrophobicContact CB-CD1 4.01Å; P136-I221 HydrophobicContact CG-CD1 3.87Å; P136-I221 HydrophobicContact CG-CG2 4.11Å; W140-I221 HydrophobicContact CH2-CD1 4.02Å; L144-I221 HydrophobicContact CD2-CD1 4.37Å; Y206-I221 HydrophobicContact CE2-CG2 4.36Å; I210-I221 HydrophobicContact CG1-CG1 4.48Å; I210-I221 HydrophobicContact CG2-CD1 3.79Å; I210-I221 HydrophobicContact CG2-CG1 3.9Å; I210-I221 HydrophobicContact CG2-CG2 4.46Å; N217-I221 PolarHBondContact O-N 2.92Å; Y218-I221 PolarHBondContact O-N 2.84Å; I221-Q223 VanDerWaalsContact C-N 3.32Å; I221-Q223 PolarHBondContact O-N 3.14Å; I221-Y224 WeakPolarHBondContact O-CB 3.46Å; I221-Y224 PolarHBondContact O-N 3.15Å; I221-A225 PolarHBondContact O-N 2.73Å
222	V	91.6	Very high	90.4	Very high	0 Å²	0	47.2 Å²	47.2	0%	0	24%	0.239	C	C	.	.	H	α-helix	trans	-62.9	-41	178.9	173.2	0	0	0	0	110.5	L154 L155 Y218 K219 Y224 A225 V226	L154-V222 HydrophobicContact CB-CG1 3.65Å; L154-V222 HydrophobicContact CD1-CG1 4.43Å; L155-V222 HydrophobicContact CD2-CG1 3.88Å; L155-V222 HydrophobicContact CD2-CG2 3.86Å; L155-V222 HydrophobicContact CG-CG1 4.12Å; L155-V222 HydrophobicContact CG-CG2 4.42Å; Y218-V222 HydrophobicContact CD1-CG2 4.01Å; Y218-V222 HydrophobicContact CD2-CG2 4.46Å; Y218-V222 HydrophobicContact CE1-CG2 3.61Å; Y218-V222 HydrophobicContact CE2-CG2 4.11Å; Y218-V222 HydrophobicContact CG-CG2 4.43Å; Y218-V222 WeakPolarHBondContact O-CG2 3.31Å; Y218-V222 PolarHBondContact O-N 3.42Å; K219-V222 PolarHBondContact O-N 3.13Å; V222-Y224 VanDerWaalsContact C-N 3.32Å; V222-Y224 PolarHBondContact O-N 3.09Å; V222-A225 PolarHBondContact O-N 2.88Å; V222-V226 HydrophobicContact CG1-CG2 4.44Å; V222-V226 WeakPolarHBondContact O-CG2 3.18Å; V222-V226 PolarHBondContact O-N 2.73Å
223	Q	92.4	Very high	90.6	Very high	103 Å²	103	41.2 Å²	41.2	48%	0.481	21%	0.207	S	C	.	.	H	α-helix	trans	-62.9	-37.1	175.2	-176.1	171.7	-26.8	0	0	112.2	L154 K219 D220 I221 V226 S227	L154-Q223 HydrophobicContact CD1-CB 4.21Å; K219-Q223 WeakPolarHBondContact O-CB 3.49Å; K219-Q223 PolarHBondContact O-N 2.8Å; D220-Q223 PolarHBondContact O-N 3.32Å; I221-Q223 VanDerWaalsContact C-N 3.32Å; I221-Q223 PolarHBondContact O-N 3.14Å; Q223-V226 PolarHBondContact O-N 2.88Å; Q223-S227 PolarHBondContact O-N 3.18Å; Q223-S227 VanDerWaalsContact O-N 3.1Å
224	Y	92.8	Very high	91.1	Very high	38 Å²	38	44.7 Å²	44.7	15%	0.149	21%	0.213	C	C	.	.	H	α-helix	trans	-64.5	-45.5	172.8	-175.7	-102.8	0	0	0	111.9	F132 Y202 F205 Y206 I210 D220 I221 V222 V226 S227 L228	F132-Y224 HydrophobicContact CD2-CD1 4.12Å; F132-Y224 HydrophobicContact CD2-CE1 4.04Å; F132-Y224 HydrophobicContact CE2-CD1 4.27Å; F132-Y224 AromaticContact CE2-CE1 3.71Å; F132-Y224 HydrophobicContact CE2-CE1 3.71Å; Y202-Y224 WeakPolarHBondContact CA-OH 3.18Å; Y202-Y224 AromaticContact CD1-CE1 3.87Å; Y202-Y224 HydrophobicContact CD1-CE1 3.87Å; Y202-Y224 HydrophobicContact CD1-CE2 4.02Å; Y202-Y224 AromaticContact CD1-CZ 3.45Å; Y202-Y224 VanDerWaalsContact CD1-CZ 3.45Å; Y202-Y224 WeakPolarHBondContact CD1-OH 3.4Å; Y202-Y224 HydrophobicContact CE1-CE2 4.05Å; Y202-Y224 AromaticContact CE1-CZ 3.96Å; Y202-Y224 PolarHBondContact O-OH 2.67Å; Y202-Y224 VanDerWaalsContact O-OH 3.06Å; F205-Y224 HydrophobicContact CD1-CD2 4.43Å; F205-Y224 AromaticContact CD1-CE2 3.54Å; F205-Y224 HydrophobicContact CD1-CE2 3.54Å; F205-Y224 AromaticContact CD1-CZ 3.62Å; F205-Y224 WeakPolarHBondContact CD1-OH 3.28Å; F205-Y224 HydrophobicContact CE1-CD2 4.36Å; F205-Y224 AromaticContact CE1-CE2 3.8Å; F205-Y224 HydrophobicContact CE1-CE2 3.8Å; Y206-Y224 HydrophobicContact CD2-CD1 4.04Å; Y206-Y224 HydrophobicContact CD2-CE1 4.03Å; I210-Y224 HydrophobicContact CD1-CD1 3.84Å; I210-Y224 HydrophobicContact CD1-CE1 4.42Å; I210-Y224 HydrophobicContact CD1-CG 4.16Å; D220-Y224 WeakPolarHBondContact O-CB 3.46Å; D220-Y224 PolarHBondContact O-N 3.35Å; I221-Y224 WeakPolarHBondContact O-CB 3.46Å; I221-Y224 PolarHBondContact O-N 3.15Å; V222-Y224 VanDerWaalsContact C-N 3.32Å; V222-Y224 PolarHBondContact O-N 3.09Å; Y224-V226 PolarHBondContact O-N 3.18Å; Y224-S227 PolarHBondContact O-N 2.04Å; Y224-S227 VanDerWaalsContact O-N 3.13Å; Y224-S227 PolarHBondContact O-OG 3.49Å; Y224-L228 PolarHBondContact O-N 3.31Å
225	A	93.8	Very high	91.5	Very high	0 Å²	0	39 Å²	39	0%	0	19%	0.192	C	C	.	.	H	α-helix	trans	-61.4	-39.8	174.8	0	0	0	0	0	112.5	F132 I133 I221 V222 S227 L228 V229	F132-A225 HydrophobicContact CB-CB 4.1Å; I133-A225 HydrophobicContact CD1-CB 4.04Å; I133-A225 HydrophobicContact CG1-CB 3.73Å; I221-A225 PolarHBondContact O-N 2.73Å; V222-A225 PolarHBondContact O-N 2.88Å; A225-S227 VanDerWaalsContact C-N 3.31Å; A225-S227 PolarHBondContact O-N 3.4Å; A225-L228 PolarHBondContact O-N 2.98Å; A225-V229 WeakPolarHBondContact O-CG2 3.45Å; A225-V229 PolarHBondContact O-N 3.09Å
226	V	94.4	Very high	91.9	Very high	10 Å²	10	37.2 Å²	37.2	6%	0.061	18%	0.182	C	C	.	.	H	α-helix	trans	-57	-45.2	172.3	174.5	0	0	0	0	110.8	L154 V158 V222 Q223 Y224 L228 V229 D230	L154-V226 HydrophobicContact CB-CG2 4.07Å; L154-V226 HydrophobicContact CD2-CG2 4.15Å; V158-V226 HydrophobicContact CG2-CB 4.3Å; V158-V226 HydrophobicContact CG2-CG2 3.39Å; V222-V226 HydrophobicContact CG1-CG2 4.44Å; V222-V226 WeakPolarHBondContact O-CG2 3.18Å; V222-V226 PolarHBondContact O-N 2.73Å; Q223-V226 PolarHBondContact O-N 2.88Å; Y224-V226 PolarHBondContact O-N 3.18Å; V226-L228 VanDerWaalsContact C-N 3.3Å; V226-L228 PolarHBondContact O-N 3.39Å; V226-V229 PolarHBondContact O-N 3.39Å; V226-V229 VanDerWaalsContact O-N 3.14Å; V226-D230 WeakPolarHBondContact CG1-OD2 3.45Å; V226-D230 PolarHBondContact O-N 2.84Å
227	S	95	Very high	92.1	Very high	43 Å²	43	38.4 Å²	38.4	30%	0.301	18%	0.184	S	C	.	.	H	α-helix	trans	-63.8	-33.5	-178.7	79.9	0	0	0	0	113.4	Q223 Y224 A225 A231	Q223-S227 PolarHBondContact O-N 3.18Å; Q223-S227 VanDerWaalsContact O-N 3.1Å; Y224-S227 PolarHBondContact O-N 2.04Å; Y224-S227 VanDerWaalsContact O-N 3.13Å; Y224-S227 PolarHBondContact O-OG 3.49Å; A225-S227 VanDerWaalsContact C-N 3.31Å; A225-S227 PolarHBondContact O-N 3.4Å; S227-A231 PolarHBondContact O-N 3.42Å
228	L	94.1	Very high	92.1	Very high	1 Å²	1	39.6 Å²	39.6	1%	0.005	19%	0.19	C	C	.	.	H	α-helix	trans	-64.8	-47.4	172	172.8	58.5	0	0	0	110.8	P129 F132 Y202 Y224 A225 V226 D230 A231 L232	P129-L228 HydrophobicContact CG-CD2 4.07Å; P129-L228 HydrophobicContact CG-CG 4.39Å; F132-L228 HydrophobicContact CD2-CD2 3.99Å; F132-L228 HydrophobicContact CE2-CD2 3.64Å; F132-L228 HydrophobicContact CZ-CD2 4.37Å; Y202-L228 HydrophobicContact CD1-CB 3.68Å; Y202-L228 HydrophobicContact CD1-CD1 3.96Å; Y202-L228 HydrophobicContact CD1-CD2 4.49Å; Y202-L228 HydrophobicContact CD1-CG 4.24Å; Y202-L228 HydrophobicContact CD2-CD1 4.05Å; Y202-L228 HydrophobicContact CE1-CB 3.71Å; Y202-L228 HydrophobicContact CE1-CD1 4.36Å; Y202-L228 HydrophobicContact CE2-CD1 4.44Å; Y202-L228 HydrophobicContact CG-CB 4.39Å; Y202-L228 HydrophobicContact CG-CD1 3.78Å; Y202-L228 HydrophobicContact CG-CG 4.49Å; Y224-L228 PolarHBondContact O-N 3.31Å; A225-L228 PolarHBondContact O-N 2.98Å; V226-L228 VanDerWaalsContact C-N 3.3Å; V226-L228 PolarHBondContact O-N 3.39Å; L228-D230 VanDerWaalsContact C-N 3.3Å; L228-D230 PolarHBondContact O-N 3.48Å; L228-A231 PolarHBondContact O-N 2.97Å; L228-L232 HydrophobicContact CD1-CD1 3.87Å; L228-L232 HydrophobicContact CD1-CG 4.06Å; L228-L232 HydrophobicContact CG-CD1 3.87Å; L228-L232 HydrophobicContact CG-CG 4.49Å; L228-L232 WeakPolarHBondContact O-CB 3.43Å; L228-L232 VanDerWaalsContact O-CG 3.26Å; L228-L232 WeakPolarHBondContact O-CG 3.4Å; L228-L232 PolarHBondContact O-N 2.82Å
229	V	95.1	Very high	92	Very high	0 Å²	0	38.3 Å²	38.3	0%	0	19%	0.186	C	C	.	.	H	α-helix	trans	-63	-38.2	179.2	-178	0	0	0	0	111.3	P129 V158 K161 L162 A225 V226 L232 L233	P129-V229 HydrophobicContact CB-CG2 3.47Å; P129-V229 VanDerWaalsContact CB-CG2 3.47Å; P129-V229 HydrophobicContact CG-CG2 3.65Å; V158-V229 HydrophobicContact CG1-CG2 4.39Å; K161-V229 HydrophobicContact CB-CG1 3.47Å; K161-V229 VanDerWaalsContact CB-CG1 3.47Å; K161-V229 HydrophobicContact CD-CG1 4.24Å; K161-V229 HydrophobicContact CG-CG1 4.45Å; L162-V229 HydrophobicContact CD2-CG1 4.37Å; L162-V229 HydrophobicContact CD2-CG2 4.08Å; L162-V229 HydrophobicContact CG-CG2 4.43Å; A225-V229 WeakPolarHBondContact O-CG2 3.45Å; A225-V229 PolarHBondContact O-N 3.09Å; V226-V229 PolarHBondContact O-N 3.39Å; V226-V229 VanDerWaalsContact O-N 3.14Å; V229-L232 PolarHBondContact O-N 2.9Å; V229-L233 HydrophobicContact CG1-CD1 4.35Å; V229-L233 WeakPolarHBondContact O-CB 3Å; V229-L233 WeakPolarHBondContact O-CG 3.41Å; V229-L233 PolarHBondContact O-N 2.88Å
230	D	94.5	Very high	91.9	Very high	46 Å²	46	36.4 Å²	36.4	25%	0.246	18%	0.18	C	C	.	.	H	α-helix	trans	-64.7	-45.3	175	-74.3	-32.9	0	0	0	111.9	K161 V226 L228 L232 L233 F234	K161-D230 WeakPolarHBondContact CD-OD1 3.34Å; K161-D230 WeakPolarHBondContact CE-OD1 3.37Å; K161-D230 IonicContact NZ-OD1 3.48Å; K161-D230 PolarHBondContact NZ-OD1 2.77Å; K161-D230 IonicContact NZ-OD2 2.98Å; K161-D230 PolarHBondContact NZ-OD2 3.46Å; V226-D230 WeakPolarHBondContact CG1-OD2 3.45Å; V226-D230 PolarHBondContact O-N 2.84Å; L228-D230 VanDerWaalsContact C-N 3.3Å; L228-D230 PolarHBondContact O-N 3.48Å; D230-L232 VanDerWaalsContact C-N 3.33Å; D230-L232 PolarHBondContact O-N 3.35Å; D230-L233 PolarHBondContact O-N 2.75Å; D230-F234 HydrophobicContact CB-CE2 4.44Å; D230-F234 WeakPolarHBondContact O-CD2 3.3Å; D230-F234 PolarHBondContact O-N 2.88Å
231	A	94.1	Very high	91.6	Very high	18 Å²	18	37 Å²	37	15%	0.149	19%	0.185	C	C	.	.	H	α-helix	trans	-59	-42.9	174	0	0	0	0	0	112.2	F198 S227 L228 F234 I235	F198-A231 HydrophobicContact CD1-CB 4.16Å; F198-A231 HydrophobicContact CE1-CB 4.17Å; S227-A231 PolarHBondContact O-N 3.42Å; L228-A231 PolarHBondContact O-N 2.97Å; A231-F234 PolarHBondContact O-N 2.86Å; A231-I235 WeakPolarHBondContact O-CG1 3.38Å; A231-I235 PolarHBondContact O-N 2.89Å
232	L	92.7	Very high	91.1	Very high	6 Å²	6	38.9 Å²	38.9	3%	0.031	20%	0.195	C	C	.	.	H	α-helix	trans	-64.2	-40.1	176.3	-69.5	166.6	0	0	0	112.3	V125 P129 L165 V199 L228 V229 D230 I235 H236	V125-L232 HydrophobicContact CG1-CD1 4.02Å; V125-L232 HydrophobicContact CG1-CD2 3.92Å; V125-L232 HydrophobicContact CG1-CG 4.45Å; V125-L232 HydrophobicContact CG2-CD2 4.15Å; P129-L232 HydrophobicContact CG-CD1 4.36Å; L165-L232 HydrophobicContact CD2-CB 4.05Å; L165-L232 HydrophobicContact CD2-CD1 4.38Å; V199-L232 HydrophobicContact CG2-CD2 4.47Å; L228-L232 HydrophobicContact CD1-CD1 3.87Å; L228-L232 HydrophobicContact CD1-CG 4.06Å; L228-L232 HydrophobicContact CG-CD1 3.87Å; L228-L232 HydrophobicContact CG-CG 4.49Å; L228-L232 WeakPolarHBondContact O-CB 3.43Å; L228-L232 VanDerWaalsContact O-CG 3.26Å; L228-L232 WeakPolarHBondContact O-CG 3.4Å; L228-L232 PolarHBondContact O-N 2.82Å; V229-L232 PolarHBondContact O-N 2.9Å; D230-L232 VanDerWaalsContact C-N 3.33Å; D230-L232 PolarHBondContact O-N 3.35Å; L232-I235 PolarHBondContact O-N 2.86Å; L232-H236 WeakPolarHBondContact O-CB 3.14Å; L232-H236 PolarHBondContact O-N 3.01Å
233	L	93.3	Very high	90.4	Very high	11 Å²	11	39 Å²	39	6%	0.058	20%	0.196	C	C	.	.	H	α-helix	trans	-65.4	-41.3	173.6	-79.5	173.6	0	0	0	112.1	K161 I164 L165 V229 D230 I235 H236 Y237	K161-L233 HydrophobicContact CB-CD1 3.75Å; K161-L233 HydrophobicContact CD-CD1 4.26Å; K161-L233 HydrophobicContact CG-CD1 3.78Å; I164-L233 HydrophobicContact CG2-CD2 4.02Å; L165-L233 HydrophobicContact CB-CD2 4.09Å; L165-L233 HydrophobicContact CD1-CD2 4.12Å; V229-L233 HydrophobicContact CG1-CD1 4.35Å; V229-L233 WeakPolarHBondContact O-CB 3Å; V229-L233 WeakPolarHBondContact O-CG 3.41Å; V229-L233 PolarHBondContact O-N 2.88Å; D230-L233 PolarHBondContact O-N 2.75Å; L233-I235 PolarHBondContact O-N 3.22Å; L233-H236 CarbonylContact O-C 3.57Å; L233-H236 WeakPolarHBondContact O-CB 3.46Å; L233-H236 PolarHBondContact O-N 2.86Å; L233-H236 VanDerWaalsContact O-N 3.14Å; L233-Y237 HydrophobicContact CB-CE2 4.19Å; L233-Y237 WeakPolarHBondContact O-CD2 3.34Å; L233-Y237 PolarHBondContact O-N 3.02Å
234	F	93.3	Very high	89.7	Confident	148 Å²	148	37 Å²	37	65%	0.649	19%	0.187	S	C	*	.	H	α-helix	trans	-62.5	-41.3	174.3	-75.1	-61.2	0	0	0	112.4	D230 A231 H236 Y237 L238	D230-F234 HydrophobicContact CB-CE2 4.44Å; D230-F234 WeakPolarHBondContact O-CD2 3.3Å; D230-F234 PolarHBondContact O-N 2.88Å; A231-F234 PolarHBondContact O-N 2.86Å; F234-H236 VanDerWaalsContact C-N 3.3Å; F234-H236 PolarHBondContact O-N 3.46Å; F234-Y237 PolarHBondContact O-N 3.32Å; F234-L238 WeakPolarHBondContact O-CB 3.22Å; F234-L238 PolarHBondContact O-N 2.86Å
235	I	91.4	Very high	88.9	Confident	13 Å²	13	39.8 Å²	39.8	7%	0.067	20%	0.203	C	C	.	.	H	α-helix	trans	-64.1	-37.1	173.3	-64.8	164.9	0	0	0	110.8	L191 L194 I195 F198 A231 L232 L233 L238 A239	L191-I235 HydrophobicContact CD2-CG2 4.15Å; L194-I235 HydrophobicContact CD2-CD1 4.35Å; L194-I235 HydrophobicContact CD2-CG1 4.1Å; L194-I235 HydrophobicContact CD2-CG2 4.25Å; L194-I235 HydrophobicContact CG-CD1 4.28Å; I195-I235 HydrophobicContact CD1-CG2 4.17Å; I195-I235 HydrophobicContact CG1-CG2 3.72Å; F198-I235 HydrophobicContact CB-CD1 4.42Å; F198-I235 HydrophobicContact CD1-CD1 4.33Å; F198-I235 HydrophobicContact CD2-CD1 4.03Å; F198-I235 HydrophobicContact CE2-CD1 4.38Å; F198-I235 HydrophobicContact CG-CD1 4Å; A231-I235 WeakPolarHBondContact O-CG1 3.38Å; A231-I235 PolarHBondContact O-N 2.89Å; L232-I235 PolarHBondContact O-N 2.86Å; L233-I235 PolarHBondContact O-N 3.22Å; I235-L238 PolarHBondContact O-N 2.8Å; I235-A239 WeakPolarHBondContact O-CB 3.45Å; I235-A239 PolarHBondContact O-N 2.9Å
236	H	89.6	Confident	87.8	Confident	15 Å²	15	45.3 Å²	45.3	7%	0.069	22%	0.224	C	C	.	.	H	α-helix	trans	-65.9	-43.4	175.2	-176.5	67.5	0	0	0	112.8	L165 G168 L172 L232 L233 F234 A239 I240	L165-H236 HydrophobicContact CD1-CB 3.97Å; G168-H236 VanDerWaalsContact CA-CE1 3.5Å; G168-H236 WeakPolarHBondContact CA-CE1 3.38Å; G168-H236 VanDerWaalsContact CA-NE2 3.35Å; G168-H236 WeakPolarHBondContact CA-NE2 3.42Å; G168-H236 PolarHBondContact O-CE1 2.87Å; G168-H236 VanDerWaalsContact O-CE1 3.3Å; L172-H236 WeakPolarHBondContact CD1-CE1 3.46Å; L232-H236 WeakPolarHBondContact O-CB 3.14Å; L232-H236 PolarHBondContact O-N 3.01Å; L233-H236 CarbonylContact O-C 3.57Å; L233-H236 WeakPolarHBondContact O-CB 3.46Å; L233-H236 PolarHBondContact O-N 2.86Å; L233-H236 VanDerWaalsContact O-N 3.14Å; F234-H236 VanDerWaalsContact C-N 3.3Å; F234-H236 PolarHBondContact O-N 3.46Å; H236-A239 WeakPolarHBondContact O-CA 3.22Å; H236-A239 VanDerWaalsContact O-CB 3.31Å; H236-A239 WeakPolarHBondContact O-CB 3.48Å; H236-A239 PolarHBondContact O-N 3.24Å; H236-A239 VanDerWaalsContact O-N 3.13Å; H236-I240 PolarHBondContact O-N 3.35Å
237	Y	90.1	Very high	86.7	Confident	112 Å²	112	46.1 Å²	46.1	44%	0.439	23%	0.227	S	C	.	.	H	α-helix	trans	-63.5	-41.1	173.8	-64	-47.3	0	0	0	111.8	L233 F234 A239 I240 V241	L233-Y237 HydrophobicContact CB-CE2 4.19Å; L233-Y237 WeakPolarHBondContact O-CD2 3.34Å; L233-Y237 PolarHBondContact O-N 3.02Å; F234-Y237 PolarHBondContact O-N 3.32Å; Y237-A239 VanDerWaalsContact C-N 3.28Å; Y237-A239 PolarHBondContact O-N 3.42Å; Y237-I240 HydrophobicContact CD1-CD1 4.32Å; Y237-I240 PolarHBondContact O-N 2.84Å; Y237-V241 WeakPolarHBondContact O-CG2 3.36Å; Y237-V241 PolarHBondContact O-N 3Å
238	L	88.6	Confident	85.6	Confident	78 Å²	78	50.2 Å²	50.2	41%	0.408	25%	0.245	S	C	.	.	H	α-helix	trans	-59.8	-39	171.7	-179.7	62.4	0	0	0	111.6	F234 I235 V241 L242	F234-L238 WeakPolarHBondContact O-CB 3.22Å; F234-L238 PolarHBondContact O-N 2.86Å; I235-L238 PolarHBondContact O-N 2.8Å; L238-V241 PolarHBondContact O-N 2.84Å; L238-L242 HydrophobicContact CD1-CD1 3.91Å; L238-L242 HydrophobicContact CD1-CG 4.03Å; L238-L242 HydrophobicContact CG-CD1 3.87Å; L238-L242 HydrophobicContact CG-CG 4.36Å; L238-L242 WeakPolarHBondContact O-CB 3.35Å; L238-L242 VanDerWaalsContact O-CG 3.32Å; L238-L242 WeakPolarHBondContact O-CG 3.33Å; L238-L242 PolarHBondContact O-N 3.2Å
239	A	86.4	Confident	84.8	Confident	6 Å²	6	57 Å²	57	5%	0.05	28%	0.277	C	S	.	.	H	α-helix	trans	-62.1	-44.5	174	0	0	0	0	0	111.9	L172 L191 I235 H236 Y237 V241 L242 L243	L172-A239 HydrophobicContact CD1-CB 4.07Å; L191-A239 HydrophobicContact CD1-CB 3.65Å; L191-A239 HydrophobicContact CD2-CB 4.22Å; I235-A239 WeakPolarHBondContact O-CB 3.45Å; I235-A239 PolarHBondContact O-N 2.9Å; H236-A239 WeakPolarHBondContact O-CA 3.22Å; H236-A239 VanDerWaalsContact O-CB 3.31Å; H236-A239 WeakPolarHBondContact O-CB 3.48Å; H236-A239 PolarHBondContact O-N 3.24Å; H236-A239 VanDerWaalsContact O-N 3.13Å; Y237-A239 VanDerWaalsContact C-N 3.28Å; Y237-A239 PolarHBondContact O-N 3.42Å; A239-V241 VanDerWaalsContact C-N 3.33Å; A239-V241 PolarHBondContact O-N 2.93Å; A239-L242 PolarHBondContact O-N 3.33Å; A239-L243 HydrophobicContact CB-CD1 4.38Å; A239-L243 WeakPolarHBondContact O-CB 3.3Å; A239-L243 WeakPolarHBondContact O-CG 3.38Å; A239-L243 PolarHBondContact O-N 3.43Å
240	I	85.8	Confident	84.1	Confident	56 Å²	56	60.8 Å²	60.8	29%	0.287	30%	0.302	S	S	.	.	H	α-helix	trans	-59.1	-44.9	174.8	-65.8	167.2	0	0	0	110.9	L172 H236 Y237 E244 L245	L172-I240 HydrophobicContact CD1-CG1 4.15Å; L172-I240 HydrophobicContact CD2-CG1 4.49Å; H236-I240 PolarHBondContact O-N 3.35Å; Y237-I240 HydrophobicContact CD1-CD1 4.32Å; Y237-I240 PolarHBondContact O-N 2.84Å; I240-E244 PolarHBondContact O-N 3Å; I240-L245 HydrophobicContact CG2-CD1 4.38Å; I240-L245 PolarHBondContact O-N 2.75Å
241	V	83.8	Confident	83.7	Confident	73 Å²	73	61.4 Å²	61.4	44%	0.442	30%	0.304	S	S	.	.	I	π-helix	trans	-62.1	-47	179.3	174.1	0	0	0	0	111.9	Y237 L238 A239 L245 R246	Y237-V241 WeakPolarHBondContact O-CG2 3.36Å; Y237-V241 PolarHBondContact O-N 3Å; L238-V241 PolarHBondContact O-N 2.84Å; A239-V241 VanDerWaalsContact C-N 3.33Å; A239-V241 PolarHBondContact O-N 2.93Å; V241-L245 HydrophobicContact CB-CD1 4.46Å; V241-L245 HydrophobicContact CG2-CD1 3.89Å; V241-R246 PolarHBondContact O-N 3.39Å
242	L	79.6	Confident	83.6	Confident	39 Å²	39	61 Å²	61	20%	0.204	30%	0.298	C	S	.	.	I	π-helix	trans	-75.6	-33.5	-177.4	-67.5	176.1	0	0	0	113.7	F187 L238 A239	F187-L242 HydrophobicContact CD1-CD1 4.39Å; L238-L242 HydrophobicContact CD1-CD1 3.91Å; L238-L242 HydrophobicContact CD1-CG 4.03Å; L238-L242 HydrophobicContact CG-CD1 3.87Å; L238-L242 HydrophobicContact CG-CG 4.36Å; L238-L242 WeakPolarHBondContact O-CB 3.35Å; L238-L242 VanDerWaalsContact O-CG 3.32Å; L238-L242 WeakPolarHBondContact O-CG 3.33Å; L238-L242 PolarHBondContact O-N 3.2Å; A239-L242 PolarHBondContact O-N 3.33Å
243	L	78.3	Confident	83.6	Confident	4 Å²	4	62.8 Å²	62.8	2%	0.021	31%	0.31	C	S	.	.	I	π-helix	trans	-95.6	-29.3	-171.9	-59.6	-176.9	0	0	0	114.4	F185 F187 R188 L191 A239 Q247	F185-L243 HydrophobicContact CD1-CD2 3.83Å; F185-L243 HydrophobicContact CE1-CD2 3.58Å; F187-L243 HydrophobicContact CB-CD2 4.18Å; R188-L243 HydrophobicContact CG-CD1 3.97Å; R188-L243 HydrophobicContact CG-CD2 3.95Å; L191-L243 HydrophobicContact CD1-CD1 4.2Å; L191-L243 HydrophobicContact CD1-CD2 4.42Å; L191-L243 HydrophobicContact CD1-CG 4.24Å; A239-L243 HydrophobicContact CB-CD1 4.38Å; A239-L243 WeakPolarHBondContact O-CB 3.3Å; A239-L243 WeakPolarHBondContact O-CG 3.38Å; A239-L243 PolarHBondContact O-N 3.43Å; L243-Q247 VanDerWaalsContact O-CD 3.24Å; L243-Q247 PolarHBondContact O-NE2 3.13Å; L243-Q247 PolarHBondContact O-OE1 2.96Å
244	E	77.3	Confident	83.7	Confident	61 Å²	61	62.2 Å²	62.2	29%	0.285	31%	0.307	S	S	.	.	I	π-helix	trans	-117.1	-61.3	-176.9	-60.3	-66.5	145.5	0	0	111.5	L172 I240 R246 Q247	L172-E244 HydrophobicContact CD2-CG 4.31Å; I240-E244 PolarHBondContact O-N 3Å; E244-R246 PolarHBondContact O-N 3.25Å; E244-Q247 PolarHBondContact O-N 3.43Å; E244-Q247 VanDerWaalsContact O-N 3.09Å
245	L	75.1	Confident	83.8	Confident	95 Å²	95	58.1 Å²	58.1	50%	0.497	29%	0.29	S	S	.	.	I	π-helix	trans	-58.9	-42.2	-171	-77.9	160.9	0	0	0	113.6	I240 V241 Q247 L248	I240-L245 HydrophobicContact CG2-CD1 4.38Å; I240-L245 PolarHBondContact O-N 2.75Å; V241-L245 HydrophobicContact CB-CD1 4.46Å; V241-L245 HydrophobicContact CG2-CD1 3.89Å; L245-Q247 PolarHBondContact O-N 3.19Å; L245-Q247 VanDerWaalsContact O-N 3.08Å; L245-L248 HydrophobicContact CD2-CD1 4.47Å; L245-L248 PolarHBondContact O-N 3.23Å
246	R	71.6	Confident	84	Confident	117 Å²	117	57.5 Å²	57.5	44%	0.442	29%	0.287	S	S	.	.	H	α-helix	trans	-59.6	-21.3	-179.8	-171.1	177.8	179.1	174.5	4.4	114.2	V241 E244 H271	V241-R246 PolarHBondContact O-N 3.39Å; E244-R246 PolarHBondContact O-N 3.25Å; R246-H271 HydrophobicContact CG-CB 4.12Å
247	Q	71.4	Confident	84.2	Confident	26 Å²	26	58.7 Å²	58.7	12%	0.121	30%	0.295	C	S	.	.	H	α-helix	trans	-97.4	-15.2	-173.8	-65.9	161.2	31.3	0	0	113.3	L243 E244 L245 L272	L243-Q247 VanDerWaalsContact O-CD 3.24Å; L243-Q247 PolarHBondContact O-NE2 3.13Å; L243-Q247 PolarHBondContact O-OE1 2.96Å; E244-Q247 PolarHBondContact O-N 3.43Å; E244-Q247 VanDerWaalsContact O-N 3.09Å; L245-Q247 PolarHBondContact O-N 3.19Å; L245-Q247 VanDerWaalsContact O-N 3.08Å; Q247-L272 HydrophobicContact CB-CD2 4.13Å; Q247-L272 HydrophobicContact CG-CD2 3.7Å
248	L	72.7	Confident	84.3	Confident	130 Å²	130	53.4 Å²	53.4	68%	0.681	27%	0.274	S	S	*	.	H	α-helix	trans	-75	-25.9	-177.5	-66.6	173.8	0	0	0	113.4	L245 P250	L245-L248 HydrophobicContact CD2-CD1 4.47Å; L245-L248 PolarHBondContact O-N 3.23Å; L248-P250 WeakPolarHBondContact O-CD 3.43Å
249	Q	76.3	Confident	84.3	Confident	142 Å²	142	52.7 Å²	52.7	66%	0.664	28%	0.276	S	S	*	.	S	Bend	trans	-80.5	115.1	176.1	-70.1	-174.3	-16.6	0	0	110.2	M251 G270	Q249-M251 PolarHBondContact O-N 2.89Å; Q249-G270 WeakPolarHBondContact O-CA 3.12Å
250	P	80.8	Confident	84.2	Confident	81 Å²	81	54.4 Å²	54.4	53%	0.526	29%	0.286	S	S	.	.			trans	-68.3	125.5	175.8	28.8	-33.4	0	0	0	109.9	L248 I499	L248-P250 WeakPolarHBondContact O-CD 3.43Å; P250-I499 HydrophobicContact CB-CD1 4.11Å
251	M	85.6	Confident	84	Confident	59 Å²	59	55 Å²	55	29%	0.291	29%	0.289	S	S	.	.			trans	-123.8	-19.1	176.1	-176	169.3	-64.3	0	0	112.6	Q249 L269 H271 K498 I499	Q249-M251 PolarHBondContact O-N 2.89Å; M251-L269 PolarHBondContact N-O 3.43Å; M251-H271 WeakPolarHBondContact CE-NE2 3.41Å; M251-H271 PolarHBondContact SD-CE1 3.12Å; M251-H271 PolarHBondContact SD-NE2 2.98Å; M251-K498 HydrophobicContact CG-CG 4.28Å; M251-I499 PolarHBondContact O-N 3.4Å
252	F	91.3	Very high	84.1	Confident	8 Å²	8	53.6 Å²	53.6	4%	0.035	29%	0.29	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-125.4	140.7	-178.2	-56.5	-80.6	0	0	0	110.9	L254 S268 L269 H271 L477 V496 K497 K498	F252-L254 HydrophobicContact CB-CD1 4.38Å; F252-S268 CarbonylContact O-C 3.6Å; F252-S268 WeakPolarHBondContact O-CA 3.42Å; F252-L269 PolarHBondContact N-O 3.35Å; F252-L269 PolarHBondContact O-N 3.37Å; F252-H271 AromaticContact CE2-ND1 3.92Å; F252-L477 HydrophobicContact CB-CD1 4.4Å; F252-L477 HydrophobicContact CD2-CB 3.88Å; F252-L477 HydrophobicContact CD2-CD1 4.13Å; F252-L477 HydrophobicContact CE2-CB 3.88Å; F252-L477 HydrophobicContact CG-CB 4.21Å; F252-L477 HydrophobicContact CG-CD1 4.39Å; F252-L477 HydrophobicContact CZ-CB 4.21Å; F252-L477 WeakPolarHBondContact CZ-O 3.38Å; F252-V496 HydrophobicContact CB-CG1 4.04Å; F252-V496 HydrophobicContact CD1-CG1 3.86Å; F252-V496 HydrophobicContact CG-CG1 4.14Å; F252-K497 CarbonylContact C-O 3.57Å; F252-K497 VanDerWaalsContact CA-O 3.28Å; F252-K497 WeakPolarHBondContact CA-O 3.46Å; F252-K498 HydrophobicContact CD1-CB 4.26Å; F252-K498 HydrophobicContact CE1-CB 4.28Å; F252-K498 HydrophobicContact CE1-CG 4.4Å
253	T	93.4	Very high	84.6	Confident	44 Å²	44	53.1 Å²	53.1	27%	0.27	29%	0.287	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-105.8	122.9	165.4	-56.8	0	0	0	0	108	F266 Y267 K497 I499	T253-F266 HydrophobicContact CG2-CB 4.28Å; T253-F266 HydrophobicContact CG2-CD1 4.2Å; T253-Y267 CarbonylContact C-O 3.6Å; T253-Y267 WeakPolarHBondContact CA-O 3.21Å; T253-K497 PolarHBondContact N-O 3.14Å; T253-K497 PolarHBondContact O-N 3.12Å; T253-I499 WeakPolarHBondContact OG1-CG1 3.44Å
254	L	94.9	Very high	85.2	Confident	0 Å²	0	55.3 Å²	55.3	0%	0	30%	0.302	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-101	123	176.7	-60.9	87.2	0	0	0	108.6	F252 F266 Y267 L269 A277 V281 L477 F483 V494 N495 V496	F252-L254 HydrophobicContact CB-CD1 4.38Å; L254-F266 WeakPolarHBondContact O-CA 3.48Å; L254-Y267 PolarHBondContact N-O 3.41Å; L254-Y267 PolarHBondContact O-N 3.26Å; L254-L269 HydrophobicContact CD1-CB 3.74Å; L254-L269 HydrophobicContact CD1-CD1 3.49Å; L254-L269 VanDerWaalsContact CD1-CD1 3.49Å; L254-L269 HydrophobicContact CD1-CG 3.56Å; L254-L269 HydrophobicContact CD2-CD1 4.05Å; L254-L269 HydrophobicContact CG-CD1 4.44Å; L254-A277 HydrophobicContact CD2-CB 4.33Å; L254-V281 HydrophobicContact CD2-CG2 4.38Å; L254-L477 HydrophobicContact CD1-CD1 4.38Å; L254-L477 HydrophobicContact CD2-CD1 4.42Å; L254-F483 HydrophobicContact CD2-CE1 4Å; L254-F483 HydrophobicContact CD2-CZ 4.09Å; L254-V494 HydrophobicContact CB-CG1 3.9Å; L254-V494 HydrophobicContact CD2-CG1 3.65Å; L254-V494 HydrophobicContact CG-CG1 4.29Å; L254-N495 CarbonylContact C-O 3.48Å; L254-N495 WeakPolarHBondContact CA-O 3.36Å; L254-V496 HydrophobicContact CD2-CG2 3.99Å; L254-V496 HydrophobicContact CG-CG2 4.18Å
255	Q	95.6	Very high	86	Confident	61 Å²	61	57 Å²	57	29%	0.285	31%	0.306	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-89.1	112	166.6	-176.9	179.5	4.5	0	0	107.9	V257 F266 V494 N495	Q255-V257 HydrophobicContact CG-CG2 3.93Å; Q255-F266 HydrophobicContact CB-CD1 3.88Å; Q255-F266 HydrophobicContact CB-CE1 3.63Å; Q255-F266 HydrophobicContact CG-CD1 4.1Å; Q255-F266 HydrophobicContact CG-CE1 3.51Å; Q255-F266 HydrophobicContact CG-CZ 3.89Å; Q255-V494 WeakPolarHBondContact O-CA 3.36Å; Q255-N495 HydrophobicContact CB-CB 4.45Å; Q255-N495 PolarHBondContact N-O 3.02Å; Q255-N495 PolarHBondContact O-N 2.83Å
256	V	95.6	Very high	86.9	Confident	0 Å²	0	58.8 Å²	58.8	0%	0	31%	0.31	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-100.1	123.5	176.2	-178	0	0	0	0	107.5	S264 R265 Y267 V281 F289 L492 V494	V256-S264 CarbonylContact O-C 3.5Å; V256-S264 WeakPolarHBondContact O-CA 3.42Å; V256-S264 WeakPolarHBondContact O-CB 3.13Å; V256-R265 PolarHBondContact N-O 2.97Å; V256-R265 PolarHBondContact O-N 2.84Å; V256-Y267 HydrophobicContact CB-CD2 4.41Å; V256-Y267 HydrophobicContact CB-CE2 4.18Å; V256-Y267 HydrophobicContact CG2-CD2 3.64Å; V256-Y267 HydrophobicContact CG2-CE2 3.82Å; V256-V281 HydrophobicContact CB-CG1 4.41Å; V256-V281 HydrophobicContact CG1-CG1 3.81Å; V256-V281 HydrophobicContact CG2-CB 4.38Å; V256-V281 HydrophobicContact CG2-CG1 3.65Å; V256-V281 HydrophobicContact CG2-CG2 3.81Å; V256-F289 HydrophobicContact CB-CE2 4.48Å; V256-F289 HydrophobicContact CB-CZ 4.05Å; V256-F289 HydrophobicContact CG1-CE2 4.17Å; V256-F289 HydrophobicContact CG1-CZ 3.69Å; V256-L492 HydrophobicContact CG1-CB 4.04Å; V256-L492 HydrophobicContact CG1-CD1 4.37Å; V256-L492 HydrophobicContact CG1-CD2 4.46Å; V256-V494 HydrophobicContact CG1-CG2 4.35Å; V256-V494 HydrophobicContact CG2-CG1 4.03Å; V256-V494 HydrophobicContact CG2-CG2 4.16Å
257	V	94.7	Very high	87.9	Confident	41 Å²	41	54.2 Å²	54.2	25%	0.248	29%	0.293	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-124.6	127.6	-179.5	-170.4	0	0	0	0	109.6	Q255 E263 L492 V493	Q255-V257 HydrophobicContact CG-CG2 3.93Å; V257-E263 WeakPolarHBondContact CA-O 3.38Å; V257-L492 CarbonylContact O-C 3.56Å; V257-L492 WeakPolarHBondContact O-CA 3.36Å; V257-V493 PolarHBondContact N-O 3Å; V257-V493 PolarHBondContact O-N 3.21Å
258	R	91.2	Very high	88.9	Confident	0 Å²	0	56.7 Å²	56.7	0%	0	31%	0.313	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-77	125.7	171.7	179.9	161.3	62	-153.3	-0.8	109.9	T260 D261 G262 E263 Y285 F289 T290 F490 L492	R258-T260 PolarHBondContact O-N 3.02Å; R258-D261 WeakPolarHBondContact CB-OD1 3.19Å; R258-D261 WeakPolarHBondContact CG-OD1 3.42Å; R258-D261 IonicContact CZ-OD1 3.96Å; R258-D261 IonicContact CZ-OD2 3.84Å; R258-D261 VanDerWaalsContact NE-CG 3.33Å; R258-D261 IonicContact NE-OD1 3.92Å; R258-D261 PolarHBondContact NE-OD1 3.45Å; R258-D261 IonicContact NE-OD2 2.83Å; R258-D261 PolarHBondContact NE-OD2 2.69Å; R258-D261 IonicContact NH2-OD1 3.18Å; R258-D261 IonicContact NH2-OD2 2.69Å; R258-D261 PolarHBondContact NH2-OD2 3.3Å; R258-G262 WeakPolarHBondContact O-CA 3.49Å; R258-G262 PolarHBondContact O-N 2.87Å; R258-E263 IonicContact CZ-OE2 3.47Å; R258-E263 PolarHBondContact N-O 3.36Å; R258-E263 IonicContact NH2-OE2 3.07Å; R258-E263 PolarHBondContact NH2-OE2 2.89Å; R258-Y285 PolarHBondContact NH1-OH 3.29Å; R258-F289 HydrophobicContact CB-CE1 4.33Å; R258-T290 PolarHBondContact NH1-O 2.92Å; R258-T290 PolarHBondContact NH2-O 3.02Å; R258-T290 PolarHBondContact NH2-OG1 3.04Å; R258-F490 HydrophobicContact CG-CD2 3.74Å; R258-F490 HydrophobicContact CG-CE2 4.18Å; R258-F490 HydrophobicContact CG-CG 4.43Å; R258-L492 HydrophobicContact CB-CD2 3.88Å; R258-L492 HydrophobicContact CG-CD2 4.27Å
259	S	88.9	Confident	89.7	Confident	63 Å²	63	51.4 Å²	51.4	44%	0.441	29%	0.285	S	S	.	.	T	Hydrogen-bonded Turn	trans	-70.9	-14.2	-168.3	59.9	0	0	0	0	115.4	S491	S259-S491 WeakPolarHBondContact CB-O 3.38Å; S259-S491 VanDerWaalsContact CB-OG 3.32Å; S259-S491 WeakPolarHBondContact CB-OG 3.37Å; S259-S491 PolarHBondContact N-O 3.33Å; S259-S491 PolarHBondContact OG-N 2.95Å; S259-S491 PolarHBondContact OG-O 3.3Å; S259-S491 PolarHBondContact OG-OG 3.49Å
260	T	83.9	Confident	90.2	Very high	43 Å²	43	44.8 Å²	44.8	26%	0.264	26%	0.256	S	S	.	.	T	Hydrogen-bonded Turn	trans	-95.3	-39.4	-173.7	43.5	0	0	0	0	113.7	R258 Y292 L297 F490	R258-T260 PolarHBondContact O-N 3.02Å; T260-Y292 HydrophobicContact CG2-CE2 4.11Å; T260-Y292 WeakPolarHBondContact OG1-CE2 3.35Å; T260-L297 VanDerWaalsContact O-CD1 3.25Å; T260-L297 WeakPolarHBondContact O-CD1 3.4Å; T260-L297 WeakPolarHBondContact O-CD2 3.17Å; T260-F490 HydrophobicContact CG2-CB 3.51Å
261	D	82.8	Confident	90.3	Very high	67 Å²	67	44 Å²	44	36%	0.358	24%	0.244	S	C	.	.	T	Hydrogen-bonded Turn	trans	-121.5	-8.6	-177.6	66.4	-16.9	0	0	0	114.4	R258 E263 L297	R258-D261 WeakPolarHBondContact CB-OD1 3.19Å; R258-D261 WeakPolarHBondContact CG-OD1 3.42Å; R258-D261 IonicContact CZ-OD1 3.96Å; R258-D261 IonicContact CZ-OD2 3.84Å; R258-D261 VanDerWaalsContact NE-CG 3.33Å; R258-D261 IonicContact NE-OD1 3.92Å; R258-D261 PolarHBondContact NE-OD1 3.45Å; R258-D261 IonicContact NE-OD2 2.83Å; R258-D261 PolarHBondContact NE-OD2 2.69Å; R258-D261 IonicContact NH2-OD1 3.18Å; R258-D261 IonicContact NH2-OD2 2.69Å; R258-D261 PolarHBondContact NH2-OD2 3.3Å; D261-E263 VanDerWaalsContact C-N 3.3Å; D261-E263 PolarHBondContact O-N 3.37Å; D261-E263 PolarHBondContact OD1-N 3.31Å; D261-L297 HydrophobicContact CB-CD1 4.45Å; D261-L297 HydrophobicContact CB-CD2 4.03Å
262	G	85.9	Confident	90.2	Very high	44 Å²	44	41.8 Å²	41.8	45%	0.454	23%	0.234	S	C	.	.			trans	75	11.7	180	0	0	0	0	0	114.8	R258 S264	R258-G262 WeakPolarHBondContact O-CA 3.49Å; R258-G262 PolarHBondContact O-N 2.87Å; G262-S264 PolarHBondContact O-N 2.96Å
263	E	88.3	Confident	90.1	Very high	30 Å²	30	42 Å²	42	14%	0.14	24%	0.236	C	C	.	.			trans	-57.2	129.2	170.7	-172.8	179.5	176.3	0	0	108.2	V257 R258 D261 R265 F289 T290	V257-E263 WeakPolarHBondContact CA-O 3.38Å; R258-E263 IonicContact CZ-OE2 3.47Å; R258-E263 PolarHBondContact N-O 3.36Å; R258-E263 IonicContact NH2-OE2 3.07Å; R258-E263 PolarHBondContact NH2-OE2 2.89Å; D261-E263 VanDerWaalsContact C-N 3.3Å; D261-E263 PolarHBondContact O-N 3.37Å; D261-E263 PolarHBondContact OD1-N 3.31Å; E263-R265 IonicContact OE1-CZ 2.73Å; E263-R265 IonicContact OE1-NE 3.47Å; E263-R265 PolarHBondContact OE1-NE 3.39Å; E263-R265 IonicContact OE1-NH2 3Å; E263-R265 PolarHBondContact OE1-NH2 3.45Å; E263-F289 HydrophobicContact CB-CD1 4.22Å; E263-F289 HydrophobicContact CB-CE1 4.35Å; E263-F289 HydrophobicContact CG-CD1 3.96Å; E263-F289 HydrophobicContact CG-CE1 4.21Å; E263-F289 WeakPolarHBondContact O-CE1 3.14Å; E263-T290 PolarHBondContact OE1-N 3.5Å; E263-T290 WeakPolarHBondContact OE2-CB 3.37Å; E263-T290 PolarHBondContact OE2-N 3.4Å; E263-T290 PolarHBondContact OE2-OG1 3.5Å
264	S	92.8	Very high	89.9	Confident	49 Å²	49	39.9 Å²	39.9	34%	0.343	22%	0.223	S	C	.	.	E	Extended strand (participates in β ladder)	trans	-131.7	142	-178.2	67.9	0	0	0	0	113	V256 G262	V256-S264 CarbonylContact O-C 3.5Å; V256-S264 WeakPolarHBondContact O-CA 3.42Å; V256-S264 WeakPolarHBondContact O-CB 3.13Å; G262-S264 PolarHBondContact O-N 2.96Å
265	R	93.1	Very high	89.6	Confident	98 Å²	98	41 Å²	41	37%	0.37	23%	0.229	S	C	.	.	E	Extended strand (participates in β ladder)	trans	-133.8	154.7	176.9	-60	-63.9	177.5	137.6	4.4	109.9	V256 E263 Y267 D288 F289	V256-R265 PolarHBondContact N-O 2.97Å; V256-R265 PolarHBondContact O-N 2.84Å; E263-R265 IonicContact OE1-CZ 2.73Å; E263-R265 IonicContact OE1-NE 3.47Å; E263-R265 PolarHBondContact OE1-NE 3.39Å; E263-R265 IonicContact OE1-NH2 3Å; E263-R265 PolarHBondContact OE1-NH2 3.45Å; R265-Y267 HydrophobicContact CB-CE2 3.88Å; R265-D288 PolarHBondContact NH2-O 3.17Å; R265-F289 HydrophobicContact CB-CD2 4.46Å; R265-F289 HydrophobicContact CB-CE2 3.65Å; R265-F289 HydrophobicContact CB-CZ 3.88Å; R265-F289 HydrophobicContact CG-CD2 3.79Å; R265-F289 HydrophobicContact CG-CE1 4.3Å; R265-F289 HydrophobicContact CG-CE2 3.41Å; R265-F289 VanDerWaalsContact CG-CE2 3.41Å; R265-F289 HydrophobicContact CG-CG 4.41Å; R265-F289 HydrophobicContact CG-CZ 3.69Å
266	F	93.9	Very high	89.2	Confident	131 Å²	131	42.2 Å²	42.2	58%	0.575	23%	0.231	S	C	*	.	E	Extended strand (participates in β ladder)	trans	-116.5	133	179.9	-63.9	-89.1	0	0	0	110.1	T253 L254 Q255	T253-F266 HydrophobicContact CG2-CB 4.28Å; T253-F266 HydrophobicContact CG2-CD1 4.2Å; L254-F266 WeakPolarHBondContact O-CA 3.48Å; Q255-F266 HydrophobicContact CB-CD1 3.88Å; Q255-F266 HydrophobicContact CB-CE1 3.63Å; Q255-F266 HydrophobicContact CG-CD1 4.1Å; Q255-F266 HydrophobicContact CG-CE1 3.51Å; Q255-F266 HydrophobicContact CG-CZ 3.89Å
267	Y	93.3	Very high	88.9	Confident	22 Å²	22	42.2 Å²	42.2	9%	0.086	23%	0.231	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-129.8	133.2	-179.4	-59.4	-64.4	0	0	0	111.3	T253 L254 V256 R265 N284 D288 F289	T253-Y267 CarbonylContact C-O 3.6Å; T253-Y267 WeakPolarHBondContact CA-O 3.21Å; L254-Y267 PolarHBondContact N-O 3.41Å; L254-Y267 PolarHBondContact O-N 3.26Å; V256-Y267 HydrophobicContact CB-CD2 4.41Å; V256-Y267 HydrophobicContact CB-CE2 4.18Å; V256-Y267 HydrophobicContact CG2-CD2 3.64Å; V256-Y267 HydrophobicContact CG2-CE2 3.82Å; R265-Y267 HydrophobicContact CB-CE2 3.88Å; Y267-N284 HydrophobicContact CD1-CB 4.14Å; Y267-N284 WeakPolarHBondContact CD1-ND2 3.47Å; Y267-N284 HydrophobicContact CE1-CB 3.53Å; Y267-N284 HydrophobicContact CE2-CB 4.08Å; Y267-N284 VanDerWaalsContact CZ-CB 3.48Å; Y267-N284 PolarHBondContact OH-O 2.96Å; Y267-D288 VanDerWaalsContact CE1-OD2 3.29Å; Y267-D288 WeakPolarHBondContact CE1-OD2 3.39Å; Y267-D288 PolarHBondContact OH-OD2 3.4Å; Y267-F289 HydrophobicContact CE2-CE2 4.22Å; Y267-F289 WeakPolarHBondContact OH-CE2 3.33Å
268	S	91.5	Very high	88.8	Confident	78 Å²	78	40.5 Å²	40.5	55%	0.545	22%	0.22	S	C	.	.	E	Extended strand (participates in β ladder)	trans	-94	121.7	175	-57.8	0	0	0	0	110.3	F252	F252-S268 CarbonylContact O-C 3.6Å; F252-S268 WeakPolarHBondContact O-CA 3.42Å
269	L	90	Very high	88.7	Confident	18 Å²	18	42.5 Å²	42.5	9%	0.094	23%	0.231	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-126.3	152.4	178.3	-60.8	-178.6	0	0	0	111.5	M251 F252 L254 L272 A277 V280	M251-L269 PolarHBondContact N-O 3.43Å; F252-L269 PolarHBondContact N-O 3.35Å; F252-L269 PolarHBondContact O-N 3.37Å; L254-L269 HydrophobicContact CD1-CB 3.74Å; L254-L269 HydrophobicContact CD1-CD1 3.49Å; L254-L269 VanDerWaalsContact CD1-CD1 3.49Å; L254-L269 HydrophobicContact CD1-CG 3.56Å; L254-L269 HydrophobicContact CD2-CD1 4.05Å; L254-L269 HydrophobicContact CG-CD1 4.44Å; L269-L272 HydrophobicContact CB-CD1 4.13Å; L269-L272 HydrophobicContact CD1-CD1 4.02Å; L269-L272 HydrophobicContact CD2-CD1 4.19Å; L269-L272 HydrophobicContact CG-CD1 4.34Å; L269-A277 HydrophobicContact CD1-CB 3.92Å; L269-V280 HydrophobicContact CD1-CB 4.49Å; L269-V280 HydrophobicContact CD2-CB 4.33Å; L269-V280 HydrophobicContact CD2-CG1 3.68Å
270	G	86.1	Confident	88.7	Confident	4 Å²	4	41 Å²	41	4%	0.041	22%	0.219	C	C	.	.			trans	-84	-158.2	170.9	0	0	0	0	0	113.6	Q249 L272	Q249-G270 WeakPolarHBondContact O-CA 3.12Å; G270-L272 VanDerWaalsContact C-N 3.32Å; G270-L272 PolarHBondContact O-N 3.19Å
271	H	82.9	Confident	89.1	Confident	63 Å²	63	39 Å²	39	29%	0.292	21%	0.207	S	C	.	.	S	Bend	trans	-71.8	82.3	177.9	-72.5	-70.9	0	0	0	112.5	R246 M251 F252	R246-H271 HydrophobicContact CG-CB 4.12Å; M251-H271 WeakPolarHBondContact CE-NE2 3.41Å; M251-H271 PolarHBondContact SD-CE1 3.12Å; M251-H271 PolarHBondContact SD-NE2 2.98Å; F252-H271 AromaticContact CE2-ND1 3.92Å
272	L	85	Confident	89.4	Confident	14 Å²	14	36.9 Å²	36.9	7%	0.073	20%	0.195	C	C	.	.			trans	-103.7	161.4	172.8	-62.6	173	0	0	0	110.8	Q247 L269 G270 R276 A277 V280 G476 L477	Q247-L272 HydrophobicContact CB-CD2 4.13Å; Q247-L272 HydrophobicContact CG-CD2 3.7Å; L269-L272 HydrophobicContact CB-CD1 4.13Å; L269-L272 HydrophobicContact CD1-CD1 4.02Å; L269-L272 HydrophobicContact CD2-CD1 4.19Å; L269-L272 HydrophobicContact CG-CD1 4.34Å; G270-L272 VanDerWaalsContact C-N 3.32Å; G270-L272 PolarHBondContact O-N 3.19Å; L272-R276 HydrophobicContact CB-CB 4.46Å; L272-R276 HydrophobicContact CD2-CG 4.02Å; L272-A277 HydrophobicContact CB-CB 4.37Å; L272-V280 HydrophobicContact CD1-CG2 4.43Å; L272-G476 CarbonylContact O-C 3.55Å; L272-G476 WeakPolarHBondContact O-CA 3.49Å; L272-L477 PolarHBondContact O-N 3.06Å
273	S	87.9	Confident	89.5	Confident	12 Å²	12	39.3 Å²	39.3	8%	0.084	20%	0.195	C	C	.	.	B	Isolated β-bridge	trans	-75.9	157.2	163.1	59.1	0	0	0	0	110.6	Q275 R276 A277 N475	S273-Q275 PolarHBondContact O-N 2.7Å; S273-R276 PolarHBondContact O-N 3.36Å; S273-R276 PolarHBondContact OG-N 3.03Å; S273-A277 WeakPolarHBondContact O-CB 3.37Å; S273-A277 PolarHBondContact O-N 2.78Å; S273-N475 CarbonylContact C-O 3.6Å; S273-N475 WeakPolarHBondContact CA-O 3.46Å; S273-N475 WeakPolarHBondContact CB-O 3.47Å
274	I	90.1	Very high	89.5	Confident	0 Å²	0	39.6 Å²	39.6	0%	0	20%	0.197	C	C	.	.	H	α-helix	trans	-52.2	-44.3	175.6	-59.3	167.2	0	0	0	110.2	R276 A277 A278 L467 E471 N475 L477 I481 F483	I274-R276 PolarHBondContact O-N 3.43Å; I274-A277 PolarHBondContact O-N 2.98Å; I274-A278 VanDerWaalsContact O-CB 3.3Å; I274-A278 WeakPolarHBondContact O-CB 3.35Å; I274-A278 PolarHBondContact O-N 2.99Å; I274-L467 HydrophobicContact CG2-CD1 4.3Å; I274-L467 HydrophobicContact CG2-CD2 4.37Å; I274-E471 HydrophobicContact CD1-CB 3.94Å; I274-N475 PolarHBondContact N-O 3.48Å; I274-L477 HydrophobicContact CG1-CD2 4.3Å; I274-I481 HydrophobicContact CD1-CD1 4.14Å; I274-I481 HydrophobicContact CD1-CG2 4.33Å; I274-I481 HydrophobicContact CG1-CD1 4.44Å; I274-F483 HydrophobicContact CG2-CB 4.02Å; I274-F483 HydrophobicContact CG2-CD1 3.82Å; I274-F483 HydrophobicContact CG2-CD2 4.29Å; I274-F483 HydrophobicContact CG2-CE1 4.3Å; I274-F483 HydrophobicContact CG2-CG 3.8Å
275	Q	88.8	Confident	89.3	Confident	23 Å²	23	37.4 Å²	37.4	11%	0.107	18%	0.182	C	C	.	.	H	α-helix	trans	-60.3	-38.7	176.5	-174.4	175.8	8	0	0	114.2	V181 P182 S273 L279 L467 V473	V181-Q275 HydrophobicContact CG1-CG 4.21Å; P182-Q275 VanDerWaalsContact CD-NE2 3.31Å; S273-Q275 PolarHBondContact O-N 2.7Å; Q275-L279 PolarHBondContact O-N 2.87Å; Q275-L467 HydrophobicContact CB-CD2 4.27Å; Q275-V473 HydrophobicContact CB-CB 4.33Å; Q275-V473 WeakPolarHBondContact CB-O 3.43Å; Q275-V473 PolarHBondContact N-O 3.34Å
276	R	86.1	Confident	88.9	Confident	87 Å²	87	34.4 Å²	34.4	33%	0.328	17%	0.171	S	C	.	.	H	α-helix	trans	-81.6	-33.7	179.4	-170.3	168.3	173.5	-173.4	-5.6	111.9	L272 S273 I274 A278 L279 V280	L272-R276 HydrophobicContact CB-CB 4.46Å; L272-R276 HydrophobicContact CD2-CG 4.02Å; S273-R276 PolarHBondContact O-N 3.36Å; S273-R276 PolarHBondContact OG-N 3.03Å; I274-R276 PolarHBondContact O-N 3.43Å; R276-A278 VanDerWaalsContact C-N 3.33Å; R276-L279 PolarHBondContact O-N 3.49Å; R276-V280 PolarHBondContact O-N 3.02Å
277	A	90.5	Very high	88.4	Confident	0 Å²	0	34.1 Å²	34.1	0%	0	17%	0.169	C	C	.	.	H	α-helix	trans	-61.7	-42.3	170.9	0	0	0	0	0	111.3	L254 L269 L272 S273 I274 L279 V280 V281 L477 F483	L254-A277 HydrophobicContact CD2-CB 4.33Å; L269-A277 HydrophobicContact CD1-CB 3.92Å; L272-A277 HydrophobicContact CB-CB 4.37Å; S273-A277 WeakPolarHBondContact O-CB 3.37Å; S273-A277 PolarHBondContact O-N 2.78Å; I274-A277 PolarHBondContact O-N 2.98Å; A277-L279 PolarHBondContact O-N 3.15Å; A277-V280 PolarHBondContact O-N 2.98Å; A277-V281 WeakPolarHBondContact O-CG2 3.5Å; A277-V281 PolarHBondContact O-N 2.94Å; A277-L477 HydrophobicContact CB-CD1 3.87Å; A277-L477 HydrophobicContact CB-CD2 3.9Å; A277-L477 HydrophobicContact CB-CG 4.14Å; A277-F483 HydrophobicContact CB-CZ 4.34Å
278	A	91.5	Very high	88	Confident	4 Å²	4	35 Å²	35	3%	0.033	18%	0.176	C	C	.	.	H	α-helix	trans	-54.8	-46	173.3	0	0	0	0	0	113.1	I274 R276 V281 L282 L467 F483 L485	I274-A278 VanDerWaalsContact O-CB 3.3Å; I274-A278 WeakPolarHBondContact O-CB 3.35Å; I274-A278 PolarHBondContact O-N 2.99Å; R276-A278 VanDerWaalsContact C-N 3.33Å; A278-V281 WeakPolarHBondContact O-CB 3.37Å; A278-V281 PolarHBondContact O-N 2.94Å; A278-L282 WeakPolarHBondContact O-CG 3.31Å; A278-L282 PolarHBondContact O-N 2.86Å; A278-L467 HydrophobicContact CB-CD1 4.1Å; A278-L467 HydrophobicContact CB-CD2 4.06Å; A278-F483 HydrophobicContact CB-CE2 3.92Å; A278-L485 HydrophobicContact CB-CD1 4.25Å; A278-L485 HydrophobicContact CB-CD2 3.78Å; A278-L485 HydrophobicContact CB-CG 4.42Å
279	L	89.2	Confident	87.8	Confident	42 Å²	42	31.4 Å²	31.4	22%	0.22	15%	0.15	C	C	.	.	H	α-helix	trans	-62.8	-43.2	177	-70.6	175	0	0	0	112.5	A179 V181 Q275 R276 A277 V281 L282 E283	A179-L279 HydrophobicContact CB-CD1 3.91Å; A179-L279 HydrophobicContact CB-CD2 3.84Å; A179-L279 HydrophobicContact CB-CG 4.4Å; V181-L279 HydrophobicContact CG1-CD1 3.45Å; V181-L279 VanDerWaalsContact CG1-CD1 3.45Å; Q275-L279 PolarHBondContact O-N 2.87Å; R276-L279 PolarHBondContact O-N 3.49Å; A277-L279 PolarHBondContact O-N 3.15Å; L279-V281 VanDerWaalsContact C-N 3.3Å; L279-V281 PolarHBondContact O-N 2.96Å; L279-L282 PolarHBondContact O-N 3.04Å; L279-L282 VanDerWaalsContact O-N 3.13Å; L279-E283 WeakPolarHBondContact O-CG 3.43Å; L279-E283 PolarHBondContact O-N 3.47Å
280	V	89.4	Confident	87.5	Confident	33 Å²	33	32.7 Å²	32.7	20%	0.2	16%	0.159	C	C	.	.	H	α-helix	trans	-65.5	-35.1	176.3	-179.5	0	0	0	0	111.5	L269 L272 R276 A277 L282 E283 N284	L269-V280 HydrophobicContact CD1-CB 4.49Å; L269-V280 HydrophobicContact CD2-CB 4.33Å; L269-V280 HydrophobicContact CD2-CG1 3.68Å; L272-V280 HydrophobicContact CD1-CG2 4.43Å; R276-V280 PolarHBondContact O-N 3.02Å; A277-V280 PolarHBondContact O-N 2.98Å; V280-L282 VanDerWaalsContact C-N 3.35Å; V280-E283 PolarHBondContact O-N 3.29Å; V280-N284 WeakPolarHBondContact O-CB 3.23Å; V280-N284 PolarHBondContact O-N 3.12Å; V280-N284 PolarHBondContact O-ND2 3.33Å
281	V	92.3	Very high	87.2	Confident	1 Å²	1	33.3 Å²	33.3	1%	0.006	16%	0.161	C	C	.	.	H	α-helix	trans	-63.2	-39.5	171.7	166.7	0	0	0	0	111.4	L254 V256 A277 A278 L279 Y285 L485 L492 V494	L254-V281 HydrophobicContact CD2-CG2 4.38Å; V256-V281 HydrophobicContact CB-CG1 4.41Å; V256-V281 HydrophobicContact CG1-CG1 3.81Å; V256-V281 HydrophobicContact CG2-CB 4.38Å; V256-V281 HydrophobicContact CG2-CG1 3.65Å; V256-V281 HydrophobicContact CG2-CG2 3.81Å; A277-V281 WeakPolarHBondContact O-CG2 3.5Å; A277-V281 PolarHBondContact O-N 2.94Å; A278-V281 WeakPolarHBondContact O-CB 3.37Å; A278-V281 PolarHBondContact O-N 2.94Å; L279-V281 VanDerWaalsContact C-N 3.3Å; L279-V281 PolarHBondContact O-N 2.96Å; V281-Y285 VanDerWaalsContact O-CB 3.27Å; V281-Y285 WeakPolarHBondContact O-CB 3.35Å; V281-Y285 PolarHBondContact O-N 3.44Å; V281-L485 HydrophobicContact CB-CD1 4.14Å; V281-L485 HydrophobicContact CG1-CD1 3.72Å; V281-L492 HydrophobicContact CG1-CD1 4.47Å; V281-V494 HydrophobicContact CG1-CG2 4.09Å; V281-V494 HydrophobicContact CG2-CG1 4.4Å
282	L	89.5	Confident	86.9	Confident	21 Å²	21	31.6 Å²	31.6	11%	0.11	15%	0.152	C	C	.	.	H	α-helix	trans	-68.7	-45.6	175.5	-66.8	178.2	0	0	0	112.2	A278 L279 V280 N284 Y285 Y286 W465 L485 L492	A278-L282 WeakPolarHBondContact O-CG 3.31Å; A278-L282 PolarHBondContact O-N 2.86Å; L279-L282 PolarHBondContact O-N 3.04Å; L279-L282 VanDerWaalsContact O-N 3.13Å; V280-L282 VanDerWaalsContact C-N 3.35Å; L282-N284 VanDerWaalsContact C-N 3.28Å; L282-N284 PolarHBondContact O-N 2.83Å; L282-Y285 WeakPolarHBondContact O-CB 3.47Å; L282-Y285 PolarHBondContact O-N 3.14Å; L282-Y285 VanDerWaalsContact O-N 3.08Å; L282-Y286 WeakPolarHBondContact O-CD2 3.5Å; L282-Y286 PolarHBondContact O-N 3.05Å; L282-Y286 VanDerWaalsContact O-N 3.12Å; L282-W465 HydrophobicContact CD1-CB 3.74Å; L282-W465 HydrophobicContact CD1-CD2 4.29Å; L282-W465 HydrophobicContact CD1-CG 3.68Å; L282-W465 HydrophobicContact CD2-CB 4.43Å; L282-W465 HydrophobicContact CD2-CD2 3.38Å; L282-W465 VanDerWaalsContact CD2-CE2 3.48Å; L282-W465 HydrophobicContact CD2-CE3 3.75Å; L282-W465 HydrophobicContact CD2-CG 3.7Å; L282-W465 HydrophobicContact CD2-CH2 4.16Å; L282-W465 HydrophobicContact CD2-CZ2 3.88Å; L282-W465 HydrophobicContact CD2-CZ3 4.11Å; L282-W465 HydrophobicContact CG-CD2 4.49Å; L282-W465 HydrophobicContact CG-CG 4.36Å; L282-L485 HydrophobicContact CD1-CD2 4.39Å; L282-L485 HydrophobicContact CD2-CB 4.46Å; L282-L485 HydrophobicContact CD2-CD1 3.93Å; L282-L485 HydrophobicContact CG-CD1 4.04Å; L282-L492 HydrophobicContact CD2-CD1 4.28Å
283	E	87.3	Confident	86.5	Confident	95 Å²	95	31.6 Å²	31.6	44%	0.444	15%	0.152	S	C	.	.	H	α-helix	trans	-54.9	-44.8	174.6	-72.3	-179.4	179.6	0	0	111.3	L279 V280	L279-E283 WeakPolarHBondContact O-CG 3.43Å; L279-E283 PolarHBondContact O-N 3.47Å; V280-E283 PolarHBondContact O-N 3.29Å
284	N	88.7	Confident	85.9	Confident	36 Å²	36	32.9 Å²	32.9	19%	0.193	16%	0.16	C	C	.	.	H	α-helix	trans	-74.2	-29.5	176.3	-67.3	-24.9	0	0	0	113.3	Y267 V280 L282 K287 D288	Y267-N284 HydrophobicContact CD1-CB 4.14Å; Y267-N284 WeakPolarHBondContact CD1-ND2 3.47Å; Y267-N284 HydrophobicContact CE1-CB 3.53Å; Y267-N284 HydrophobicContact CE2-CB 4.08Å; Y267-N284 VanDerWaalsContact CZ-CB 3.48Å; Y267-N284 PolarHBondContact OH-O 2.96Å; V280-N284 WeakPolarHBondContact O-CB 3.23Å; V280-N284 PolarHBondContact O-N 3.12Å; V280-N284 PolarHBondContact O-ND2 3.33Å; L282-N284 VanDerWaalsContact C-N 3.28Å; L282-N284 PolarHBondContact O-N 2.83Å; N284-K287 PolarHBondContact O-N 3.23Å; N284-D288 WeakPolarHBondContact O-CB 3.42Å; N284-D288 PolarHBondContact O-N 2.87Å
285	Y	87.9	Confident	85.1	Confident	4 Å²	4	35.9 Å²	35.9	2%	0.016	18%	0.176	C	C	.	.	H	α-helix	trans	-59.6	-51.3	175.3	172.4	-98.4	0	0	0	111	R258 V281 L282 K287 F289 W465 F490 L492	R258-Y285 PolarHBondContact NH1-OH 3.29Å; V281-Y285 VanDerWaalsContact O-CB 3.27Å; V281-Y285 WeakPolarHBondContact O-CB 3.35Å; V281-Y285 PolarHBondContact O-N 3.44Å; L282-Y285 WeakPolarHBondContact O-CB 3.47Å; L282-Y285 PolarHBondContact O-N 3.14Å; L282-Y285 VanDerWaalsContact O-N 3.08Å; Y285-K287 PolarHBondContact O-N 3.2Å; Y285-K287 VanDerWaalsContact O-N 3.16Å; Y285-F289 HydrophobicContact CD2-CB 3.65Å; Y285-F289 AromaticContact CD2-CD1 3.79Å; Y285-F289 HydrophobicContact CD2-CD1 3.79Å; Y285-F289 AromaticContact CD2-CD2 3.59Å; Y285-F289 HydrophobicContact CD2-CD2 3.59Å; Y285-F289 HydrophobicContact CD2-CE1 4.29Å; Y285-F289 HydrophobicContact CD2-CE2 4.11Å; Y285-F289 AromaticContact CD2-CG 3.4Å; Y285-F289 HydrophobicContact CD2-CG 3.4Å; Y285-F289 HydrophobicContact CD2-CZ 4.44Å; Y285-F289 HydrophobicContact CE2-CB 3.57Å; Y285-F289 AromaticContact CE2-CD1 3.72Å; Y285-F289 HydrophobicContact CE2-CD1 3.72Å; Y285-F289 HydrophobicContact CE2-CD2 4.29Å; Y285-F289 HydrophobicContact CE2-CE1 4.45Å; Y285-F289 AromaticContact CE2-CG 3.61Å; Y285-F289 HydrophobicContact CE2-CG 3.61Å; Y285-F289 HydrophobicContact CG-CB 4.48Å; Y285-F289 HydrophobicContact CG-CD2 4.37Å; Y285-F289 HydrophobicContact CG-CG 4.43Å; Y285-F289 WeakPolarHBondContact O-CB 3.33Å; Y285-F289 PolarHBondContact O-N 2.84Å; Y285-W465 HydrophobicContact CD1-CH2 4.44Å; Y285-W465 HydrophobicContact CD1-CZ2 4.05Å; Y285-W465 HydrophobicContact CE1-CH2 4.37Å; Y285-W465 HydrophobicContact CE1-CZ2 4.05Å; Y285-F490 HydrophobicContact CE1-CZ 4.2Å; Y285-F490 HydrophobicContact CE2-CE2 4.27Å; Y285-F490 AromaticContact CZ-CE2 3.92Å; Y285-F490 AromaticContact CZ-CZ 3.75Å; Y285-F490 WeakPolarHBondContact OH-CZ 3.26Å; Y285-L492 HydrophobicContact CD1-CD1 4.42Å; Y285-L492 HydrophobicContact CD2-CD1 3.57Å; Y285-L492 HydrophobicContact CD2-CD2 3.72Å; Y285-L492 HydrophobicContact CD2-CG 4.26Å; Y285-L492 HydrophobicContact CE2-CD1 4.25Å; Y285-L492 HydrophobicContact CE2-CD2 3.72Å; Y285-L492 HydrophobicContact CG-CD1 3.69Å
286	Y	84.5	Confident	84.3	Confident	35 Å²	35	38.6 Å²	38.6	14%	0.137	19%	0.191	C	C	.	.	H	α-helix	trans	-63	-22.6	179.3	-75.8	-69.9	0	0	0	113.5	L282 P451 T452 L453 S462 W465	L282-Y286 WeakPolarHBondContact O-CD2 3.5Å; L282-Y286 PolarHBondContact O-N 3.05Å; L282-Y286 VanDerWaalsContact O-N 3.12Å; Y286-P451 WeakPolarHBondContact O-CB 3.43Å; Y286-T452 HydrophobicContact CD1-CG2 3.85Å; Y286-T452 HydrophobicContact CE1-CG2 4.06Å; Y286-T452 PolarHBondContact O-N 3.48Å; Y286-L453 WeakPolarHBondContact O-CD1 3.31Å; Y286-L453 WeakPolarHBondContact O-CG 3.48Å; Y286-L453 PolarHBondContact O-N 3.44Å; Y286-S462 PolarHBondContact OH-O 3.12Å; Y286-W465 AromaticContact CE2-NE1 3.87Å; Y286-W465 AromaticContact CZ-NE1 3.75Å; Y286-W465 PolarHBondContact OH-NE1 3.03Å
287	K	83.6	Confident	83.3	Confident	124 Å²	124	37.2 Å²	37.2	54%	0.539	19%	0.19	S	C	.	.	H	α-helix	trans	-96.3	-34.6	-177	-175.8	-170.8	155.1	-93.7	0	115.1	N284 Y285 P451	N284-K287 PolarHBondContact O-N 3.23Å; Y285-K287 PolarHBondContact O-N 3.2Å; Y285-K287 VanDerWaalsContact O-N 3.16Å; K287-P451 VanDerWaalsContact O-CB 3.31Å; K287-P451 WeakPolarHBondContact O-CB 3.41Å
288	D	86.2	Confident	82.2	Confident	42 Å²	42	39.7 Å²	39.7	23%	0.225	21%	0.205	C	C	.	.	H	α-helix	trans	-119.1	-18.6	-167.8	-54.7	-39.3	0	0	0	114.4	R265 Y267 N284	R265-D288 PolarHBondContact NH2-O 3.17Å; Y267-D288 VanDerWaalsContact CE1-OD2 3.29Å; Y267-D288 WeakPolarHBondContact CE1-OD2 3.39Å; Y267-D288 PolarHBondContact OH-OD2 3.4Å; N284-D288 WeakPolarHBondContact O-CB 3.42Å; N284-D288 PolarHBondContact O-N 2.87Å
289	F	86.4	Confident	81	Confident	2 Å²	2	39.6 Å²	39.6	1%	0.009	21%	0.205	C	C	.	.	S	Bend	trans	-87.9	143.8	177.3	-79.5	-113.6	0	0	0	111.5	V256 R258 E263 R265 Y267 Y285	V256-F289 HydrophobicContact CB-CE2 4.48Å; V256-F289 HydrophobicContact CB-CZ 4.05Å; V256-F289 HydrophobicContact CG1-CE2 4.17Å; V256-F289 HydrophobicContact CG1-CZ 3.69Å; R258-F289 HydrophobicContact CB-CE1 4.33Å; E263-F289 HydrophobicContact CB-CD1 4.22Å; E263-F289 HydrophobicContact CB-CE1 4.35Å; E263-F289 HydrophobicContact CG-CD1 3.96Å; E263-F289 HydrophobicContact CG-CE1 4.21Å; E263-F289 WeakPolarHBondContact O-CE1 3.14Å; R265-F289 HydrophobicContact CB-CD2 4.46Å; R265-F289 HydrophobicContact CB-CE2 3.65Å; R265-F289 HydrophobicContact CB-CZ 3.88Å; R265-F289 HydrophobicContact CG-CD2 3.79Å; R265-F289 HydrophobicContact CG-CE1 4.3Å; R265-F289 HydrophobicContact CG-CE2 3.41Å; R265-F289 VanDerWaalsContact CG-CE2 3.41Å; R265-F289 HydrophobicContact CG-CG 4.41Å; R265-F289 HydrophobicContact CG-CZ 3.69Å; Y267-F289 HydrophobicContact CE2-CE2 4.22Å; Y267-F289 WeakPolarHBondContact OH-CE2 3.33Å; Y285-F289 HydrophobicContact CD2-CB 3.65Å; Y285-F289 AromaticContact CD2-CD1 3.79Å; Y285-F289 HydrophobicContact CD2-CD1 3.79Å; Y285-F289 AromaticContact CD2-CD2 3.59Å; Y285-F289 HydrophobicContact CD2-CD2 3.59Å; Y285-F289 HydrophobicContact CD2-CE1 4.29Å; Y285-F289 HydrophobicContact CD2-CE2 4.11Å; Y285-F289 AromaticContact CD2-CG 3.4Å; Y285-F289 HydrophobicContact CD2-CG 3.4Å; Y285-F289 HydrophobicContact CD2-CZ 4.44Å; Y285-F289 HydrophobicContact CE2-CB 3.57Å; Y285-F289 AromaticContact CE2-CD1 3.72Å; Y285-F289 HydrophobicContact CE2-CD1 3.72Å; Y285-F289 HydrophobicContact CE2-CD2 4.29Å; Y285-F289 HydrophobicContact CE2-CE1 4.45Å; Y285-F289 AromaticContact CE2-CG 3.61Å; Y285-F289 HydrophobicContact CE2-CG 3.61Å; Y285-F289 HydrophobicContact CG-CB 4.48Å; Y285-F289 HydrophobicContact CG-CD2 4.37Å; Y285-F289 HydrophobicContact CG-CG 4.43Å; Y285-F289 WeakPolarHBondContact O-CB 3.33Å; Y285-F289 PolarHBondContact O-N 2.84Å
290	T	83.6	Confident	79.9	Confident	45 Å²	45	40.6 Å²	40.6	28%	0.276	22%	0.215	S	C	.	.	B	Isolated β-bridge	trans	-67.1	151.2	171.5	69	0	0	0	0	110.5	R258 E263 Y292 A449	R258-T290 PolarHBondContact NH1-O 2.92Å; R258-T290 PolarHBondContact NH2-O 3.02Å; R258-T290 PolarHBondContact NH2-OG1 3.04Å; E263-T290 PolarHBondContact OE1-N 3.5Å; E263-T290 WeakPolarHBondContact OE2-CB 3.37Å; E263-T290 PolarHBondContact OE2-N 3.4Å; E263-T290 PolarHBondContact OE2-OG1 3.5Å; T290-Y292 PolarHBondContact O-N 3.15Å; T290-A449 WeakPolarHBondContact CB-O 3.4Å; T290-A449 HydrophobicContact CG2-CB 4.35Å; T290-A449 WeakPolarHBondContact CG2-O 3.46Å
291	I	79.4	Confident	78.8	Confident	17 Å²	17	46.4 Å²	46.4	9%	0.087	24%	0.237	C	C	.	.	P	Polyproline II helix	trans	-60.4	130.8	179	-173.2	157.3	0	0	0	112.3	N293 Y419 A449 Y455	I291-N293 PolarHBondContact O-N 3.46Å; I291-Y419 HydrophobicContact CD1-CD1 3.92Å; I291-Y419 HydrophobicContact CD1-CE1 3.38Å; I291-Y419 HydrophobicContact CG1-CE1 4.01Å; I291-Y419 HydrophobicContact CG2-CE2 4.29Å; I291-A449 HydrophobicContact CG2-CB 4.33Å; I291-Y455 HydrophobicContact CB-CD2 4.17Å; I291-Y455 HydrophobicContact CB-CE2 4.4Å; I291-Y455 HydrophobicContact CD1-CD1 4.49Å; I291-Y455 HydrophobicContact CD1-CD2 3.55Å; I291-Y455 HydrophobicContact CD1-CE2 4.44Å; I291-Y455 HydrophobicContact CD1-CG 3.59Å; I291-Y455 HydrophobicContact CG1-CD2 4.48Å; I291-Y455 HydrophobicContact CG2-CD2 4.23Å; I291-Y455 HydrophobicContact CG2-CE2 4.06Å
292	Y	76.8	Confident	77.5	Confident	26 Å²	26	53 Å²	53	10%	0.102	27%	0.266	C	S	.	.	P	Polyproline II helix	trans	-65.2	118.5	177.2	172.4	-120.1	0	0	0	111	T260 T290 P294 L297 Y419 D489 F490	T260-Y292 HydrophobicContact CG2-CE2 4.11Å; T260-Y292 WeakPolarHBondContact OG1-CE2 3.35Å; T290-Y292 PolarHBondContact O-N 3.15Å; Y292-P294 HydrophobicContact CE1-CB 3.96Å; Y292-P294 HydrophobicContact CE1-CG 4.24Å; Y292-L297 HydrophobicContact CE2-CD1 3.75Å; Y292-Y419 PolarHBondContact O-OH 2.97Å; Y292-D489 HydrophobicContact CE1-CB 3.96Å; Y292-F490 AromaticContact CD1-CD1 3.57Å; Y292-F490 HydrophobicContact CD1-CD1 3.57Å; Y292-F490 AromaticContact CD1-CE1 3.88Å; Y292-F490 HydrophobicContact CD1-CE1 3.88Å; Y292-F490 HydrophobicContact CD1-CG 4.49Å; Y292-F490 AromaticContact CE1-CD1 3.91Å; Y292-F490 HydrophobicContact CE1-CD1 3.91Å; Y292-F490 AromaticContact CG-CD1 3.97Å; Y292-F490 HydrophobicContact CG-CD1 3.97Å; Y292-F490 HydrophobicContact CG-CE1 4.15Å
293	N	77.8	Confident	76.5	Confident	14 Å²	14	54.8 Å²	54.8	8%	0.075	27%	0.271	C	S	.	.			trans	-113.9	95	177.8	-171.3	-12.1	0	0	0	111	I291 N295 L296 R415 Y419	I291-N293 PolarHBondContact O-N 3.46Å; N293-N295 PolarHBondContact O-N 3.1Å; N293-N295 VanDerWaalsContact O-N 3.16Å; N293-N295 WeakPolarHBondContact OD1-CB 3.49Å; N293-N295 PolarHBondContact OD1-N 3.25Å; N293-N295 VanDerWaalsContact OD1-N 3.15Å; N293-L296 HydrophobicContact CB-CD1 4.12Å; N293-L296 HydrophobicContact CB-CG 4.31Å; N293-L296 PolarHBondContact O-N 3.14Å; N293-R415 PolarHBondContact ND2-O 3.47Å; N293-Y419 HydrophobicContact CB-CE2 4.48Å
294	P	73.9	Confident	75.5	Confident	40 Å²	40	51.6 Å²	51.6	26%	0.26	26%	0.261	S	S	.	.	H	α-helix	trans	-60.8	-27.2	-179.2	24.7	-34.1	0	0	0	112.6	Y292 L296 L297 T298	Y292-P294 HydrophobicContact CE1-CB 3.96Å; Y292-P294 HydrophobicContact CE1-CG 4.24Å; P294-L296 VanDerWaalsContact C-N 3.26Å; P294-L296 PolarHBondContact O-N 2.82Å; P294-L297 PolarHBondContact O-N 2.83Å; P294-T298 PolarHBondContact O-N 3.35Å
295	N	73	Confident	74.4	Confident	62 Å²	62	52.5 Å²	52.5	33%	0.332	27%	0.274	S	S	.	.	H	α-helix	trans	-71.6	-18.6	-176.7	-62.2	-30.4	0	0	0	112.7	N293 T298 R415	N293-N295 PolarHBondContact O-N 3.1Å; N293-N295 VanDerWaalsContact O-N 3.16Å; N293-N295 WeakPolarHBondContact OD1-CB 3.49Å; N293-N295 PolarHBondContact OD1-N 3.25Å; N293-N295 VanDerWaalsContact OD1-N 3.15Å; N295-T298 PolarHBondContact O-OG1 3.31Å; N295-R415 HydrophobicContact CB-CB 4.18Å; N295-R415 WeakPolarHBondContact O-CD 3.43Å; N295-R415 PolarHBondContact O-NH1 3.16Å
296	L	71.8	Confident	73.3	Confident	81 Å²	81	60.3 Å²	60.3	42%	0.424	31%	0.308	S	S	.	.	H	α-helix	trans	-74.4	-37.2	171.3	-73.3	175.6	0	0	0	111.9	N293 P294 A299 T414 R415	N293-L296 HydrophobicContact CB-CD1 4.12Å; N293-L296 HydrophobicContact CB-CG 4.31Å; N293-L296 PolarHBondContact O-N 3.14Å; P294-L296 VanDerWaalsContact C-N 3.26Å; P294-L296 PolarHBondContact O-N 2.82Å; L296-A299 WeakPolarHBondContact O-CB 3.29Å; L296-A299 PolarHBondContact O-N 3.44Å; L296-T414 WeakPolarHBondContact CD2-O 3.43Å; L296-R415 HydrophobicContact CD2-CB 4.37Å
297	L	66	Low	72.2	Confident	58 Å²	58	63.5 Å²	63.5	30%	0.304	32%	0.324	S	S	.	.	H	α-helix	trans	-73.9	-32.3	-177.2	-62	173.7	0	0	0	113.2	T260 D261 Y292 P294 A299 S300	T260-L297 VanDerWaalsContact O-CD1 3.25Å; T260-L297 WeakPolarHBondContact O-CD1 3.4Å; T260-L297 WeakPolarHBondContact O-CD2 3.17Å; D261-L297 HydrophobicContact CB-CD1 4.45Å; D261-L297 HydrophobicContact CB-CD2 4.03Å; Y292-L297 HydrophobicContact CE2-CD1 3.75Å; P294-L297 PolarHBondContact O-N 2.83Å; L297-A299 VanDerWaalsContact C-N 3.32Å; L297-S300 PolarHBondContact O-OG 3.06Å
298	T	67.1	Low	71.1	Confident	51 Å²	51	63.1 Å²	63.1	31%	0.313	33%	0.326	S	S	.	.	H	α-helix	trans	-75	-23.7	172.5	58.3	0	0	0	0	112.3	P294 N295 S300 K301 F302	P294-T298 PolarHBondContact O-N 3.35Å; N295-T298 PolarHBondContact O-OG1 3.31Å; T298-S300 VanDerWaalsContact C-N 3.34Å; T298-S300 PolarHBondContact O-N 3.06Å; T298-K301 PolarHBondContact O-N 2.68Å; T298-F302 WeakPolarHBondContact O-CD2 3.36Å; T298-F302 PolarHBondContact O-N 3.27Å
299	A	66.8	Low	70	Confident	3 Å²	3	65.1 Å²	65.1	3%	0.025	35%	0.348	C	S	.	.	H	α-helix	trans	-61.9	-37.1	-174.9	0	0	0	0	0	113.5	L296 L297 R303	L296-A299 WeakPolarHBondContact O-CB 3.29Å; L296-A299 PolarHBondContact O-N 3.44Å; L297-A299 VanDerWaalsContact C-N 3.32Å; A299-R303 WeakPolarHBondContact O-CD 3.28Å; A299-R303 WeakPolarHBondContact O-CG 3.38Å; A299-R303 PolarHBondContact O-N 2.84Å
300	S	65	Low	68.7	Low	62 Å²	62	68.1 Å²	68.1	43%	0.434	38%	0.379	S	S	.	.	H	α-helix	trans	-66.1	-45.8	175.6	55.1	0	0	0	0	111.6	L297 T298 F302 R303 A304	L297-S300 PolarHBondContact O-OG 3.06Å; T298-S300 VanDerWaalsContact C-N 3.34Å; T298-S300 PolarHBondContact O-N 3.06Å; S300-F302 PolarHBondContact O-N 3.14Å; S300-R303 PolarHBondContact O-N 2.98Å; S300-A304 PolarHBondContact O-N 3.35Å
301	K	66.4	Low	67.4	Low	156 Å²	156	71.1 Å²	71.1	68%	0.678	39%	0.393	S	S	*	.	H	α-helix	trans	-60.5	-43.2	177.5	-61.5	-177.8	-179.4	179	0	112.3	T298 A305	T298-K301 PolarHBondContact O-N 2.68Å; K301-A305 WeakPolarHBondContact O-CB 3.38Å; K301-A305 PolarHBondContact O-N 2.78Å
302	F	66.2	Low	66.4	Low	138 Å²	138	78.3 Å²	78.3	61%	0.605	42%	0.424	S	S	*	.	H	α-helix	trans	-68	-34.2	178	-80.1	-64.2	0	0	0	113.4	T298 S300 K306	T298-F302 WeakPolarHBondContact O-CD2 3.36Å; T298-F302 PolarHBondContact O-N 3.27Å; S300-F302 PolarHBondContact O-N 3.14Å; F302-K306 WeakPolarHBondContact O-CB 3.32Å; F302-K306 PolarHBondContact O-N 2.83Å; F302-K306 VanDerWaalsContact O-N 3.07Å
303	R	67.8	Low	65.3	Low	59 Å²	59	81.9 Å²	81.9	22%	0.223	45%	0.448	C	S	.	.	H	α-helix	trans	-67.5	-48.4	174.3	-66.6	166	-161.3	167.2	7.2	111.1	A299 S300 A305 K306 H307 E348 H352	A299-R303 WeakPolarHBondContact O-CD 3.28Å; A299-R303 WeakPolarHBondContact O-CG 3.38Å; A299-R303 PolarHBondContact O-N 2.84Å; S300-R303 PolarHBondContact O-N 2.98Å; R303-A305 VanDerWaalsContact C-N 3.32Å; R303-A305 PolarHBondContact O-N 2.91Å; R303-K306 WeakPolarHBondContact O-CB 3.35Å; R303-K306 PolarHBondContact O-N 2.92Å; R303-H307 PolarHBondContact O-N 3.37Å; R303-H307 VanDerWaalsContact O-N 3.13Å; R303-E348 WeakPolarHBondContact CB-OE2 3.26Å; R303-H352 PolarHBondContact NH2-CD2 3.45Å; R303-H352 PolarHBondContact NH2-CE1 3.5Å; R303-H352 PolarHBondContact NH2-ND1 3.23Å; R303-H352 PolarHBondContact NH2-NE2 3.37Å
304	A	65.6	Low	64.3	Low	28 Å²	28	89.7 Å²	89.7	23%	0.231	48%	0.478	C	S	.	.	H	α-helix	trans	-51.5	-48.6	174.1	0	0	0	0	0	112.5	S300 K306 M308 L345	S300-A304 PolarHBondContact O-N 3.35Å; A304-K306 PolarHBondContact O-N 2.96Å; A304-M308 WeakPolarHBondContact O-CG 3.45Å; A304-M308 PolarHBondContact O-N 2.79Å; A304-L345 HydrophobicContact CB-CD2 3.61Å
305	A	65.9	Low	63.2	Low	56 Å²	56	95 Å²	95	46%	0.463	50%	0.504	S	S	.	.	H	α-helix	trans	-64.5	-39.3	178.8	0	0	0	0	0	112.5	K301 R303 H307 M308 A309	K301-A305 WeakPolarHBondContact O-CB 3.38Å; K301-A305 PolarHBondContact O-N 2.78Å; R303-A305 VanDerWaalsContact C-N 3.32Å; R303-A305 PolarHBondContact O-N 2.91Å; A305-H307 PolarHBondContact O-N 3.27Å; A305-M308 PolarHBondContact O-N 2.83Å; A305-A309 WeakPolarHBondContact O-CB 3.38Å; A305-A309 PolarHBondContact O-N 3.16Å
306	K	66.2	Low	62.5	Low	168 Å²	168	98.4 Å²	98.4	73%	0.73	53%	0.527	S	S	*	.	H	α-helix	trans	-64.5	-39.9	-179.9	-175.4	174.3	-179.4	174.5	0	112.5	F302 R303 A304 A309 G310	F302-K306 WeakPolarHBondContact O-CB 3.32Å; F302-K306 PolarHBondContact O-N 2.83Å; F302-K306 VanDerWaalsContact O-N 3.07Å; R303-K306 WeakPolarHBondContact O-CB 3.35Å; R303-K306 PolarHBondContact O-N 2.92Å; A304-K306 PolarHBondContact O-N 2.96Å; K306-A309 PolarHBondContact O-N 3.4Å; K306-G310 PolarHBondContact O-N 3.11Å
307	H	61.6	Low	61.6	Low	101 Å²	101	101.4 Å²	101.4	47%	0.468	54%	0.543	S	S	.	.	H	α-helix	trans	-69.8	-40.2	177.9	-167.2	-107.5	0	0	0	112	R303 A305 A309 G310 E344	R303-H307 PolarHBondContact O-N 3.37Å; R303-H307 VanDerWaalsContact O-N 3.13Å; A305-H307 PolarHBondContact O-N 3.27Å; H307-A309 VanDerWaalsContact C-N 3.27Å; H307-A309 PolarHBondContact O-N 3.44Å; H307-G310 PolarHBondContact O-N 3.21Å; H307-G310 VanDerWaalsContact O-N 3.11Å; H307-E344 VanDerWaalsContact CB-OE1 3.26Å; H307-E344 WeakPolarHBondContact CB-OE1 3.38Å; H307-E344 IonicContact CD2-OE1 3.49Å; H307-E344 IonicContact CE1-OE1 3.71Å; H307-E344 PolarHBondContact CE1-OE1 2.88Å; H307-E344 IonicContact CE1-OE2 3.87Å; H307-E344 PolarHBondContact CE1-OE2 2.94Å; H307-E344 IonicContact CG-OE1 3.97Å; H307-E344 IonicContact CG-OE2 2.78Å; H307-E344 IonicContact ND1-OE1 2.84Å; H307-E344 PolarHBondContact ND1-OE1 3.45Å; H307-E344 IonicContact ND1-OE2 2.77Å; H307-E344 PolarHBondContact ND1-OE2 2.86Å
308	M	60.6	Low	61.2	Low	117 Å²	117	101.3 Å²	101.3	58%	0.576	56%	0.556	S	S	*	*	H	α-helix	trans	-60.1	-35.9	174.1	-66.4	-66.1	151.7	0	0	112.8	A304 A305 S341	A304-M308 WeakPolarHBondContact O-CG 3.45Å; A304-M308 PolarHBondContact O-N 2.79Å; A305-M308 PolarHBondContact O-N 2.83Å; M308-S341 VanDerWaalsContact CE-CB 3.44Å
309	A	61.5	Low	60.4	Low	83 Å²	83	106 Å²	106	69%	0.686	59%	0.587	S	S	*	*	H	α-helix	trans	-76.9	-17.7	177	0	0	0	0	0	114.4	A305 K306 H307 L311	A305-A309 WeakPolarHBondContact O-CB 3.38Å; A305-A309 PolarHBondContact O-N 3.16Å; K306-A309 PolarHBondContact O-N 3.4Å; H307-A309 VanDerWaalsContact C-N 3.27Å; H307-A309 PolarHBondContact O-N 3.44Å; A309-L311 VanDerWaalsContact C-N 3.34Å; A309-L311 PolarHBondContact O-N 3.32Å
310	G	60.1	Low	59.7	Low	65 Å²	65	110.5 Å²	110.5	67%	0.67	62%	0.618	S	S	*	*	T	Hydrogen-bonded Turn	trans	-75.7	-15.6	-174.9	0	0	0	0	0	115.3	K306 H307 K312	K306-G310 PolarHBondContact O-N 3.11Å; H307-G310 PolarHBondContact O-N 3.21Å; H307-G310 VanDerWaalsContact O-N 3.11Å; G310-K312 PolarHBondContact O-N 3.43Å
311	L	56.4	Low	59.1	Low	108 Å²	108	115 Å²	115	57%	0.565	64%	0.638	S	S	*	*			trans	-98.2	82.2	-169.6	-168	72.4	0	0	0	112.8	A309 V313	A309-L311 VanDerWaalsContact C-N 3.34Å; A309-L311 PolarHBondContact O-N 3.32Å; L311-V313 PolarHBondContact O-N 3.04Å; L311-V313 VanDerWaalsContact O-N 3.16Å
312	K	57.4	Low	58.4	Low	169 Å²	169	113.3 Å²	113.3	74%	0.735	64%	0.636	S	S	*	*			trans	-67.2	109.5	166.7	-75.2	-173.5	176.7	-177.5	0	110.2	G310 Y314	G310-K312 PolarHBondContact O-N 3.43Å; K312-Y314 HydrophobicContact CB-CE2 4.23Å; K312-Y314 PolarHBondContact O-N 3.4Å
313	V	54.1	Low	57.9	Low	100 Å²	100	109.9 Å²	109.9	61%	0.606	63%	0.633	S	S	*	*			trans	-81.2	110.8	172	-179.8	0	0	0	0	108.7	L311	L311-V313 PolarHBondContact O-N 3.04Å; L311-V313 VanDerWaalsContact O-N 3.16Å
314	Y	57.2	Low	57.2	Low	179 Å²	179	113.1 Å²	113.1	70%	0.702	66%	0.66	S	S	*	*			trans	-83.2	122.8	167	-63.3	-84.8	0	0	0	108.8	K312 V316	K312-Y314 HydrophobicContact CB-CE2 4.23Å; K312-Y314 PolarHBondContact O-N 3.4Å; Y314-V316 PolarHBondContact O-N 3.31Å
315	N	51	Low	56.6	Low	152 Å²	152	114 Å²	114	81%	0.813	67%	0.671	S	S	*	*			trans	-70.7	112.7	166	-100.3	-5.4	0	0	0	108
316	V	57	Low	56.1	Low	133 Å²	133	116.3 Å²	116.3	81%	0.806	67%	0.672	S	S	*	*			trans	-88.1	-18.8	-179.7	178.5	0	0	0	0	111.9	Y314	Y314-V316 PolarHBondContact O-N 3.31Å
317	D	54.8	Low	55.6	Low	144 Å²	144	111.4 Å²	111.4	77%	0.77	66%	0.659	S	S	*	*	S	Bend	trans	-97.7	130.9	179.1	-63.5	-47.1	0	0	0	112
318	G	56.3	Low	55.4	Low	56 Å²	56	116.5 Å²	116.5	58%	0.577	67%	0.674	S	S	*	*			trans	-66.1	175.7	172.8	0	0	0	0	0	113.3	S320	G318-S320 PolarHBondContact O-N 3.5Å
319	P	50.1	Low	55.4	Low	149 Å²	149	113.9 Å²	113.9	97%	0.968	67%	0.671	S	S	*	*	S	Bend	trans	-67.6	98.5	-167.1	28.3	-35.5	0	0	0	111.9
320	S	51.7	Low	55.3	Low	97 Å²	97	115.8 Å²	115.8	68%	0.678	67%	0.667	S	S	*	*			trans	-130	142	174.7	-166.4	0	0	0	0	111.7	G318 N322	G318-S320 PolarHBondContact O-N 3.5Å; S320-N322 PolarHBondContact O-N 3.13Å
321	N	52.6	Low	55.4	Low	158 Å²	158	118.4 Å²	118.4	85%	0.845	67%	0.665	S	S	*	*	S	Bend	trans	-93.8	41.7	-137.4	-144.8	8	0	0	0	114.7
322	N	52.9	Low	55.7	Low	119 Å²	119	115.8 Å²	115.8	64%	0.636	66%	0.659	S	S	*	*			trans	-112.4	57.5	-170.9	-79.9	-17.6	0	0	0	114	S320 T324	S320-N322 PolarHBondContact O-N 3.13Å; N322-T324 VanDerWaalsContact C-N 3.34Å; N322-T324 PolarHBondContact O-N 3.5Å
323	A	54.7	Low	55.8	Low	66 Å²	66	109.6 Å²	109.6	55%	0.545	64%	0.639	S	S	.	*	H	α-helix	trans	-60.2	-34.6	-175.8	0	0	0	0	0	114.9	S327	A323-S327 PolarHBondContact O-N 3.04Å; A323-S327 PolarHBondContact O-OG 3.21Å
324	T	54.1	Low	56.1	Low	128 Å²	128	107.5 Å²	107.5	79%	0.785	63%	0.632	S	S	*	*	H	α-helix	trans	-74.7	-32.6	-172.6	51.6	0	0	0	0	114	N322	N322-T324 VanDerWaalsContact C-N 3.34Å; N322-T324 PolarHBondContact O-N 3.5Å
325	G	53.5	Low	56.2	Low	45 Å²	45	101.4 Å²	101.4	46%	0.464	62%	0.619	S	S	.	*	H	α-helix	trans	-73.5	-38.4	174.5	0	0	0	0	0	112.4	S327 R328 A329	G325-S327 PolarHBondContact O-N 3.05Å; G325-R328 PolarHBondContact O-N 3.07Å; G325-A329 WeakPolarHBondContact O-CB 3.37Å; G325-A329 PolarHBondContact O-N 3.3Å
326	Q	54.8	Low	56.7	Low	105 Å²	105	103.7 Å²	103.7	49%	0.491	62%	0.616	S	S	.	*	H	α-helix	trans	-62.5	-42.3	179.9	-72.4	179.3	-13.1	0	0	112.3	R328 A329 M330	Q326-R328 PolarHBondContact O-N 3.28Å; Q326-A329 PolarHBondContact O-N 3.25Å; Q326-M330 HydrophobicContact CB-CE 4.3Å; Q326-M330 WeakPolarHBondContact O-CB 3.34Å; Q326-M330 WeakPolarHBondContact O-CG 3.36Å; Q326-M330 PolarHBondContact O-N 3.03Å
327	S	56	Low	56.7	Low	65 Å²	65	103.8 Å²	103.8	46%	0.455	60%	0.602	S	S	.	*	H	α-helix	trans	-61.6	-42.7	176	-56.9	0	0	0	0	112.6	A323 G325 M330 I331	A323-S327 PolarHBondContact O-N 3.04Å; A323-S327 PolarHBondContact O-OG 3.21Å; G325-S327 PolarHBondContact O-N 3.05Å; S327-M330 PolarHBondContact O-N 3.28Å; S327-I331 WeakPolarHBondContact O-CB 3.01Å; S327-I331 WeakPolarHBondContact O-CD1 3.25Å; S327-I331 WeakPolarHBondContact O-CG1 3.47Å; S327-I331 PolarHBondContact O-N 3.45Å
328	R	57.8	Low	56.9	Low	209 Å²	209	106.4 Å²	106.4	79%	0.789	60%	0.601	S	S	*	*	H	α-helix	trans	-68.5	-39.4	178.7	-121.2	177.5	177.2	175.1	-1.4	112.1	G325 Q326 I331 A332	G325-R328 PolarHBondContact O-N 3.07Å; Q326-R328 PolarHBondContact O-N 3.28Å; R328-I331 PolarHBondContact O-N 2.89Å; R328-A332 WeakPolarHBondContact O-CB 3.47Å; R328-A332 PolarHBondContact O-N 2.97Å
329	A	60.4	Low	56.9	Low	61 Å²	61	109.5 Å²	109.5	50%	0.504	60%	0.604	S	S	.	*	H	α-helix	trans	-65.8	-41.4	173.9	0	0	0	0	0	112.2	G325 Q326 A332 A333	G325-A329 WeakPolarHBondContact O-CB 3.37Å; G325-A329 PolarHBondContact O-N 3.3Å; Q326-A329 PolarHBondContact O-N 3.25Å; A329-A332 PolarHBondContact O-N 2.85Å; A329-A333 VanDerWaalsContact O-CB 3.22Å; A329-A333 WeakPolarHBondContact O-CB 3.45Å; A329-A333 PolarHBondContact O-N 3.28Å
330	M	59.4	Low	57.4	Low	123 Å²	123	105.5 Å²	105.5	61%	0.606	58%	0.58	S	S	*	*	H	α-helix	trans	-65.6	-40.6	174.5	-80	-165.1	-88.1	0	0	112.4	Q326 S327 A333 A334	Q326-M330 HydrophobicContact CB-CE 4.3Å; Q326-M330 WeakPolarHBondContact O-CB 3.34Å; Q326-M330 WeakPolarHBondContact O-CG 3.36Å; Q326-M330 PolarHBondContact O-N 3.03Å; S327-M330 PolarHBondContact O-N 3.28Å; M330-A333 PolarHBondContact O-N 3.08Å; M330-A334 WeakPolarHBondContact O-CB 3.4Å; M330-A334 PolarHBondContact O-N 2.95Å
331	I	60.5	Low	58	Low	121 Å²	121	102.1 Å²	102.1	62%	0.621	56%	0.557	S	S	*	*	H	α-helix	trans	-65.6	-43.1	175.9	-69.3	163.7	0	0	0	110.8	S327 R328 A334 A335	S327-I331 WeakPolarHBondContact O-CB 3.01Å; S327-I331 WeakPolarHBondContact O-CD1 3.25Å; S327-I331 WeakPolarHBondContact O-CG1 3.47Å; S327-I331 PolarHBondContact O-N 3.45Å; R328-I331 PolarHBondContact O-N 2.89Å; I331-A334 PolarHBondContact O-N 3.09Å; I331-A335 WeakPolarHBondContact O-CB 3.4Å; I331-A335 PolarHBondContact O-N 3.17Å
332	A	62.7	Low	58.4	Low	53 Å²	53	101.6 Å²	101.6	44%	0.438	55%	0.549	S	S	.	.	H	α-helix	trans	-66.9	-36.7	175.6	0	0	0	0	0	112.7	R328 A329 R336	R328-A332 WeakPolarHBondContact O-CB 3.47Å; R328-A332 PolarHBondContact O-N 2.97Å; A329-A332 PolarHBondContact O-N 2.85Å; A332-R336 WeakPolarHBondContact O-CG 3.27Å; A332-R336 PolarHBondContact O-N 3.26Å
333	A	61	Low	59.4	Low	39 Å²	39	99.9 Å²	99.9	32%	0.322	54%	0.54	S	S	.	.	H	α-helix	trans	-68.7	-39.7	173.2	0	0	0	0	0	111.7	A329 M330 R336 R337	A329-A333 VanDerWaalsContact O-CB 3.22Å; A329-A333 WeakPolarHBondContact O-CB 3.45Å; A329-A333 PolarHBondContact O-N 3.28Å; M330-A333 PolarHBondContact O-N 3.08Å; A333-R336 PolarHBondContact O-N 3.38Å; A333-R337 VanDerWaalsContact O-CB 3.29Å; A333-R337 WeakPolarHBondContact O-CB 3.39Å; A333-R337 WeakPolarHBondContact O-CG 3.33Å; A333-R337 PolarHBondContact O-N 3.19Å
334	A	60	Low	60.2	Low	56 Å²	56	98.7 Å²	98.7	46%	0.463	52%	0.523	S	S	.	.	H	α-helix	trans	-65.2	-39.7	175.1	0	0	0	0	0	111.8	M330 I331 R337 R338	M330-A334 WeakPolarHBondContact O-CB 3.4Å; M330-A334 PolarHBondContact O-N 2.95Å; I331-A334 PolarHBondContact O-N 3.09Å; A334-R337 PolarHBondContact O-N 3.31Å; A334-R338 PolarHBondContact O-N 3.26Å
335	A	58.9	Low	61.2	Low	51 Å²	51	95.5 Å²	95.5	42%	0.421	50%	0.5	S	S	.	.	H	α-helix	trans	-60.9	-52	172.6	0	0	0	0	0	111.4	I331 R337 R338 D339	I331-A335 WeakPolarHBondContact O-CB 3.4Å; I331-A335 PolarHBondContact O-N 3.17Å; A335-R337 VanDerWaalsContact C-N 3.28Å; A335-R337 PolarHBondContact O-N 3.2Å; A335-R338 WeakPolarHBondContact O-CB 3.21Å; A335-R338 PolarHBondContact O-N 2.98Å; A335-D339 PolarHBondContact O-N 3.18Å; A335-D339 VanDerWaalsContact O-N 3.14Å
336	R	60.9	Low	62.4	Low	200 Å²	200	100.2 Å²	100.2	76%	0.755	51%	0.505	S	S	*	.	H	α-helix	trans	-62.3	-32.1	176.1	-70.5	178.4	178.7	178	0.4	113.2	A332 A333 S340	A332-R336 WeakPolarHBondContact O-CG 3.27Å; A332-R336 PolarHBondContact O-N 3.26Å; A333-R336 PolarHBondContact O-N 3.38Å; R336-S340 WeakPolarHBondContact O-CB 3.09Å; R336-S340 PolarHBondContact O-N 3.31Å
337	R	57.3	Low	63.7	Low	134 Å²	134	102.1 Å²	102.1	51%	0.506	51%	0.509	S	S	.	.	H	α-helix	trans	-69.3	-36.3	172.7	-76.7	170.9	-176	-161.6	2.3	112.2	A333 A334 A335 S340 S341	A333-R337 VanDerWaalsContact O-CB 3.29Å; A333-R337 WeakPolarHBondContact O-CB 3.39Å; A333-R337 WeakPolarHBondContact O-CG 3.33Å; A333-R337 PolarHBondContact O-N 3.19Å; A334-R337 PolarHBondContact O-N 3.31Å; A335-R337 VanDerWaalsContact C-N 3.28Å; A335-R337 PolarHBondContact O-N 3.2Å; R337-S340 PolarHBondContact O-N 3.16Å; R337-S341 WeakPolarHBondContact O-CB 3.43Å; R337-S341 PolarHBondContact O-N 2.76Å
338	R	59.8	Low	64.9	Low	199 Å²	199	101.2 Å²	101.2	75%	0.751	50%	0.498	S	S	*	.	H	α-helix	trans	-62.1	-45.8	174.4	-170.6	176.1	179.7	174.2	-0.8	110.9	A334 A335 S341	A334-R338 PolarHBondContact O-N 3.26Å; A335-R338 WeakPolarHBondContact O-CB 3.21Å; A335-R338 PolarHBondContact O-N 2.98Å; R338-S341 PolarHBondContact O-N 3.02Å; R338-S341 PolarHBondContact O-OG 3.5Å
339	D	56.4	Low	66	Low	121 Å²	121	97.2 Å²	97.2	65%	0.647	49%	0.488	S	S	*	.	H	α-helix	trans	-66.3	-39.6	176	-59.6	-29.1	0	0	0	111.7	A335 S341	A335-D339 PolarHBondContact O-N 3.18Å; A335-D339 VanDerWaalsContact O-N 3.14Å; D339-S341 VanDerWaalsContact C-N 3.33Å; D339-S341 PolarHBondContact O-N 2.81Å
340	S	60.4	Low	67.2	Low	66 Å²	66	96.2 Å²	96.2	46%	0.462	48%	0.48	S	S	.	.	H	α-helix	trans	-61.4	-38.4	173.3	-169.4	0	0	0	0	112.8	R336 R337 H342 N343 E344	R336-S340 WeakPolarHBondContact O-CB 3.09Å; R336-S340 PolarHBondContact O-N 3.31Å; R337-S340 PolarHBondContact O-N 3.16Å; S340-H342 VanDerWaalsContact C-N 3.29Å; S340-H342 PolarHBondContact O-N 3.08Å; S340-N343 PolarHBondContact O-N 2.99Å; S340-E344 WeakPolarHBondContact O-CB 3.42Å; S340-E344 PolarHBondContact O-N 3.34Å
341	S	62.8	Low	68.5	Low	26 Å²	26	95 Å²	95	18%	0.182	47%	0.472	C	S	.	.	H	α-helix	trans	-65.4	-31	-175	73.7	0	0	0	0	113.3	M308 R337 R338 D339 E344 L345	M308-S341 VanDerWaalsContact CE-CB 3.44Å; R337-S341 WeakPolarHBondContact O-CB 3.43Å; R337-S341 PolarHBondContact O-N 2.76Å; R338-S341 PolarHBondContact O-N 3.02Å; R338-S341 PolarHBondContact O-OG 3.5Å; D339-S341 VanDerWaalsContact C-N 3.33Å; D339-S341 PolarHBondContact O-N 2.81Å; S341-E344 PolarHBondContact O-N 3.15Å; S341-L345 WeakPolarHBondContact O-CG 3.36Å; S341-L345 PolarHBondContact O-N 3.24Å
342	H	62.9	Low	69.7	Low	147 Å²	147	90.8 Å²	90.8	68%	0.681	45%	0.45	S	S	*	.	H	α-helix	trans	-68.7	-40.4	175.2	-173	-78.7	0	0	0	111.8	S340 E344 Y346	S340-H342 VanDerWaalsContact C-N 3.29Å; S340-H342 PolarHBondContact O-N 3.08Å; H342-E344 VanDerWaalsContact C-N 3.3Å; H342-Y346 PolarHBondContact O-N 3.35Å
343	N	72.7	Confident	71	Confident	83 Å²	83	92.9 Å²	92.9	44%	0.444	45%	0.451	S	S	.	.	H	α-helix	trans	-67.8	-34.5	177	-163.3	28.5	0	0	0	111.5	S340 Y346 Y347	S340-N343 PolarHBondContact O-N 2.99Å; N343-Y346 WeakPolarHBondContact O-CB 3.08Å; N343-Y347 WeakPolarHBondContact O-CD2 3.49Å; N343-Y347 PolarHBondContact O-N 2.74Å
344	E	72.5	Confident	72.4	Confident	41 Å²	41	100.3 Å²	100.3	19%	0.192	47%	0.471	C	S	.	.	H	α-helix	trans	-67.3	-45.1	177.5	-162.7	-161.2	108.2	0	0	112.7	H307 S340 S341 H342 Y346 Y347 E348	H307-E344 VanDerWaalsContact CB-OE1 3.26Å; H307-E344 WeakPolarHBondContact CB-OE1 3.38Å; H307-E344 IonicContact CD2-OE1 3.49Å; H307-E344 IonicContact CE1-OE1 3.71Å; H307-E344 PolarHBondContact CE1-OE1 2.88Å; H307-E344 IonicContact CE1-OE2 3.87Å; H307-E344 PolarHBondContact CE1-OE2 2.94Å; H307-E344 IonicContact CG-OE1 3.97Å; H307-E344 IonicContact CG-OE2 2.78Å; H307-E344 IonicContact ND1-OE1 2.84Å; H307-E344 PolarHBondContact ND1-OE1 3.45Å; H307-E344 IonicContact ND1-OE2 2.77Å; H307-E344 PolarHBondContact ND1-OE2 2.86Å; S340-E344 WeakPolarHBondContact O-CB 3.42Å; S340-E344 PolarHBondContact O-N 3.34Å; S341-E344 PolarHBondContact O-N 3.15Å; H342-E344 VanDerWaalsContact C-N 3.3Å; E344-Y346 VanDerWaalsContact C-N 3.27Å; E344-Y346 PolarHBondContact O-N 3.12Å; E344-Y347 PolarHBondContact O-N 3.34Å; E344-E348 PolarHBondContact O-N 3.04Å
345	L	73.4	Confident	73.8	Confident	61 Å²	61	102.2 Å²	102.2	32%	0.319	47%	0.466	S	S	.	.	H	α-helix	trans	-57.3	-40.1	175	-73.9	167.1	0	0	0	112.4	A304 S341 Y347 E348 E349	A304-L345 HydrophobicContact CB-CD2 3.61Å; S341-L345 WeakPolarHBondContact O-CG 3.36Å; S341-L345 PolarHBondContact O-N 3.24Å; L345-Y347 PolarHBondContact O-N 3.13Å; L345-E348 PolarHBondContact O-N 3.18Å; L345-E349 WeakPolarHBondContact O-CB 3.18Å; L345-E349 PolarHBondContact O-N 2.96Å
346	Y	79.8	Confident	75.4	Confident	144 Å²	144	101.2 Å²	101.2	57%	0.565	46%	0.455	S	S	*	.	H	α-helix	trans	-60.3	-42.9	173.8	170.7	-98.7	0	0	0	112.1	H342 N343 E344 E349 A350	H342-Y346 PolarHBondContact O-N 3.35Å; N343-Y346 WeakPolarHBondContact O-CB 3.08Å; E344-Y346 VanDerWaalsContact C-N 3.27Å; E344-Y346 PolarHBondContact O-N 3.12Å; Y346-E349 PolarHBondContact O-N 2.9Å; Y346-A350 WeakPolarHBondContact O-CB 3.38Å; Y346-A350 PolarHBondContact O-N 3.46Å
347	Y	82	Confident	76.9	Confident	144 Å²	144	97.8 Å²	97.8	57%	0.565	45%	0.445	S	S	*	.	H	α-helix	trans	-68.6	-37.6	175.6	-69.2	-58.6	0	0	0	112.9	N343 E344 L345 A350 E351	N343-Y347 WeakPolarHBondContact O-CD2 3.49Å; N343-Y347 PolarHBondContact O-N 2.74Å; E344-Y347 PolarHBondContact O-N 3.34Å; L345-Y347 PolarHBondContact O-N 3.13Å; Y347-A350 PolarHBondContact O-N 3.44Å; Y347-E351 VanDerWaalsContact O-CB 3.32Å; Y347-E351 WeakPolarHBondContact O-CB 3.46Å; Y347-E351 PolarHBondContact O-N 3.3Å
348	E	80.6	Confident	78.7	Confident	47 Å²	47	97.3 Å²	97.3	22%	0.22	45%	0.447	C	S	.	.	H	α-helix	trans	-64	-39.5	174.5	-71	-161	119.2	0	0	112.6	R303 E344 L345 H352	R303-E348 WeakPolarHBondContact CB-OE2 3.26Å; E344-E348 PolarHBondContact O-N 3.04Å; L345-E348 PolarHBondContact O-N 3.18Å; E348-H352 VanDerWaalsContact O-CB 3.27Å; E348-H352 WeakPolarHBondContact O-CB 3.41Å; E348-H352 PolarHBondContact O-N 3.34Å
349	E	82.3	Confident	80.4	Confident	124 Å²	124	91.8 Å²	91.8	58%	0.579	43%	0.426	S	S	*	.	H	α-helix	trans	-65.3	-48.8	174.6	-176.7	163.4	-134	0	0	111	L345 Y346 E351 H352 E353	L345-E349 WeakPolarHBondContact O-CB 3.18Å; L345-E349 PolarHBondContact O-N 2.96Å; Y346-E349 PolarHBondContact O-N 2.9Å; E349-E351 VanDerWaalsContact C-N 3.32Å; E349-E351 PolarHBondContact O-N 3.45Å; E349-H352 CarbonylContact O-C 3.59Å; E349-H352 WeakPolarHBondContact O-CA 3.34Å; E349-H352 WeakPolarHBondContact O-CB 3.33Å; E349-H352 PolarHBondContact O-N 3.38Å; E349-H352 VanDerWaalsContact O-N 3.1Å; E349-E353 PolarHBondContact O-N 3Å
350	A	85.7	Confident	82.2	Confident	41 Å²	41	92.5 Å²	92.5	34%	0.339	42%	0.419	S	S	.	.	H	α-helix	trans	-60.5	-38.6	175.1	0	0	0	0	0	112.7	Y346 Y347 R354	Y346-A350 WeakPolarHBondContact O-CB 3.38Å; Y346-A350 PolarHBondContact O-N 3.46Å; Y347-A350 PolarHBondContact O-N 3.44Å; A350-R354 WeakPolarHBondContact O-CB 3.5Å; A350-R354 PolarHBondContact O-N 2.69Å
351	E	86.6	Confident	83.8	Confident	96 Å²	96	92 Å²	92	45%	0.449	42%	0.42	S	S	.	.	H	α-helix	trans	-70.4	-35	175.1	-155.5	-131.2	147.2	0	0	111.6	Y347 E349 R354 R355	Y347-E351 VanDerWaalsContact O-CB 3.32Å; Y347-E351 WeakPolarHBondContact O-CB 3.46Å; Y347-E351 PolarHBondContact O-N 3.3Å; E349-E351 VanDerWaalsContact C-N 3.32Å; E349-E351 PolarHBondContact O-N 3.45Å; E351-R354 PolarHBondContact O-N 2.85Å; E351-R355 WeakPolarHBondContact O-CG 3.17Å; E351-R355 PolarHBondContact O-N 2.75Å; E351-R355 PolarHBondContact O-NE 3.07Å; E351-R355 IonicContact OE1-CZ 3.73Å; E351-R355 VanDerWaalsContact OE1-CZ 3.29Å; E351-R355 IonicContact OE1-NE 3.85Å; E351-R355 IonicContact OE1-NH1 2.85Å; E351-R355 PolarHBondContact OE1-NH1 3.16Å; E351-R355 IonicContact OE1-NH2 2.88Å; E351-R355 IonicContact OE2-CZ 3.29Å; E351-R355 IonicContact OE2-NH1 2.77Å; E351-R355 PolarHBondContact OE2-NH1 3.22Å; E351-R355 IonicContact OE2-NH2 3.72Å; E351-R355 PolarHBondContact OE2-NH2 3.33Å
352	H	85.8	Confident	85.3	Confident	34 Å²	34	97.3 Å²	97.3	16%	0.157	44%	0.435	C	S	.	.	H	α-helix	trans	-64.8	-48.4	171.7	-178.1	65.2	0	0	0	112.2	R303 E348 E349 R354 R355 V356 T413	R303-H352 PolarHBondContact NH2-CD2 3.45Å; R303-H352 PolarHBondContact NH2-CE1 3.5Å; R303-H352 PolarHBondContact NH2-ND1 3.23Å; R303-H352 PolarHBondContact NH2-NE2 3.37Å; E348-H352 VanDerWaalsContact O-CB 3.27Å; E348-H352 WeakPolarHBondContact O-CB 3.41Å; E348-H352 PolarHBondContact O-N 3.34Å; E349-H352 CarbonylContact O-C 3.59Å; E349-H352 WeakPolarHBondContact O-CA 3.34Å; E349-H352 WeakPolarHBondContact O-CB 3.33Å; E349-H352 PolarHBondContact O-N 3.38Å; E349-H352 VanDerWaalsContact O-N 3.1Å; H352-R354 VanDerWaalsContact C-N 3.28Å; H352-R354 PolarHBondContact O-N 3.43Å; H352-R355 WeakPolarHBondContact O-CA 3.29Å; H352-R355 WeakPolarHBondContact O-CB 3.4Å; H352-R355 PolarHBondContact O-N 3.17Å; H352-R355 VanDerWaalsContact O-N 3.08Å; H352-V356 WeakPolarHBondContact O-CG2 3.49Å; H352-V356 PolarHBondContact O-N 2.85Å; H352-T413 PolarHBondContact CE1-O 2.61Å
353	E	88.4	Confident	86.9	Confident	97 Å²	97	90.3 Å²	90.3	45%	0.453	40%	0.403	S	S	.	.	H	α-helix	trans	-55.2	-45.2	172.3	-74.5	-156.9	156.7	0	0	111.5	E349 R355 V356 K357	E349-E353 PolarHBondContact O-N 3Å; E353-R355 VanDerWaalsContact C-N 3.28Å; E353-R355 PolarHBondContact O-N 3.22Å; E353-V356 PolarHBondContact O-N 3.35Å; E353-K357 HydrophobicContact CB-CD 4.48Å; E353-K357 WeakPolarHBondContact O-CB 3.22Å; E353-K357 VanDerWaalsContact O-CG 3.28Å; E353-K357 WeakPolarHBondContact O-CG 3.48Å; E353-K357 PolarHBondContact O-N 3.05Å; E353-K357 IonicContact OE2-NZ 2.72Å; E353-K357 PolarHBondContact OE2-NZ 2.99Å
354	R	90.6	Very high	88	Confident	195 Å²	195	88 Å²	88	74%	0.736	39%	0.392	S	S	*	.	H	α-helix	trans	-61.3	-38.2	178.1	-169.9	-179.8	-176.2	-166.2	3	111.4	A350 E351 H352 K358	A350-R354 WeakPolarHBondContact O-CB 3.5Å; A350-R354 PolarHBondContact O-N 2.69Å; E351-R354 PolarHBondContact O-N 2.85Å; H352-R354 VanDerWaalsContact C-N 3.28Å; H352-R354 PolarHBondContact O-N 3.43Å; R354-K358 WeakPolarHBondContact O-CB 3.33Å; R354-K358 PolarHBondContact O-N 3.28Å
355	R	90.9	Very high	89.1	Confident	95 Å²	95	89.4 Å²	89.4	36%	0.358	40%	0.403	S	S	.	.	H	α-helix	trans	-64.4	-48	172.3	-75.4	176	-72.2	-137.5	1.5	111.5	E351 H352 E353 K358 R359 T413	E351-R355 WeakPolarHBondContact O-CG 3.17Å; E351-R355 PolarHBondContact O-N 2.75Å; E351-R355 PolarHBondContact O-NE 3.07Å; E351-R355 IonicContact OE1-CZ 3.73Å; E351-R355 VanDerWaalsContact OE1-CZ 3.29Å; E351-R355 IonicContact OE1-NE 3.85Å; E351-R355 IonicContact OE1-NH1 2.85Å; E351-R355 PolarHBondContact OE1-NH1 3.16Å; E351-R355 IonicContact OE1-NH2 2.88Å; E351-R355 IonicContact OE2-CZ 3.29Å; E351-R355 IonicContact OE2-NH1 2.77Å; E351-R355 PolarHBondContact OE2-NH1 3.22Å; E351-R355 IonicContact OE2-NH2 3.72Å; E351-R355 PolarHBondContact OE2-NH2 3.33Å; H352-R355 WeakPolarHBondContact O-CA 3.29Å; H352-R355 WeakPolarHBondContact O-CB 3.4Å; H352-R355 PolarHBondContact O-N 3.17Å; H352-R355 VanDerWaalsContact O-N 3.08Å; E353-R355 VanDerWaalsContact C-N 3.28Å; E353-R355 PolarHBondContact O-N 3.22Å; R355-K358 PolarHBondContact O-N 3.45Å; R355-R359 VanDerWaalsContact O-CG 3.29Å; R355-R359 WeakPolarHBondContact O-CG 3.46Å; R355-R359 PolarHBondContact O-N 2.99Å; R355-T413 HydrophobicContact CB-CG2 4.49Å
356	V	91.3	Very high	90.2	Very high	31 Å²	31	87.1 Å²	87.1	19%	0.188	39%	0.393	C	S	.	.	H	α-helix	trans	-59.9	-50	177	176.4	0	0	0	0	110.8	H352 E353 K358 R359 R360 Y410 T413 T414	H352-V356 WeakPolarHBondContact O-CG2 3.49Å; H352-V356 PolarHBondContact O-N 2.85Å; E353-V356 PolarHBondContact O-N 3.35Å; V356-K358 VanDerWaalsContact C-N 3.33Å; V356-K358 PolarHBondContact O-N 3.47Å; V356-R359 PolarHBondContact O-N 2.81Å; V356-R359 VanDerWaalsContact O-N 3.13Å; V356-R360 WeakPolarHBondContact O-CB 3.2Å; V356-R360 PolarHBondContact O-N 3.23Å; V356-Y410 HydrophobicContact CG1-CE2 4.04Å; V356-T413 HydrophobicContact CG2-CG2 3.86Å; V356-T414 HydrophobicContact CG1-CG2 4.1Å; V356-T414 HydrophobicContact CG2-CG2 4.46Å
357	K	93.7	Very high	90.9	Very high	127 Å²	127	80.3 Å²	80.3	55%	0.552	37%	0.366	S	S	*	.	H	α-helix	trans	-56.6	-43.5	176.8	-71.5	163.5	179.6	167.7	0	111.6	E353 A361	E353-K357 HydrophobicContact CB-CD 4.48Å; E353-K357 WeakPolarHBondContact O-CB 3.22Å; E353-K357 VanDerWaalsContact O-CG 3.28Å; E353-K357 WeakPolarHBondContact O-CG 3.48Å; E353-K357 PolarHBondContact O-N 3.05Å; E353-K357 IonicContact OE2-NZ 2.72Å; E353-K357 PolarHBondContact OE2-NZ 2.99Å; K357-A361 PolarHBondContact O-N 2.82Å
358	K	95.1	Very high	91.5	Very high	124 Å²	124	76.5 Å²	76.5	54%	0.539	35%	0.354	S	S	.	.	H	α-helix	trans	-67.1	-36.5	175.4	-177.6	176.3	-178.9	176.2	0	113.5	R354 R355 V356 R362	R354-K358 WeakPolarHBondContact O-CB 3.33Å; R354-K358 PolarHBondContact O-N 3.28Å; R355-K358 PolarHBondContact O-N 3.45Å; V356-K358 VanDerWaalsContact C-N 3.33Å; V356-K358 PolarHBondContact O-N 3.47Å; K358-R362 WeakPolarHBondContact O-CG 3.45Å; K358-R362 PolarHBondContact O-N 3.28Å
359	R	93.7	Very high	92.2	Very high	84 Å²	84	80.4 Å²	80.4	32%	0.317	37%	0.372	S	S	.	.	H	α-helix	trans	-70.7	-45	175.2	-68.9	-68.1	-176.8	-154.1	-5.1	111.1	R355 V356 A361 R362 L363 Y410	R355-R359 VanDerWaalsContact O-CG 3.29Å; R355-R359 WeakPolarHBondContact O-CG 3.46Å; R355-R359 PolarHBondContact O-N 2.99Å; V356-R359 PolarHBondContact O-N 2.81Å; V356-R359 VanDerWaalsContact O-N 3.13Å; R359-A361 PolarHBondContact O-N 3.17Å; R359-R362 PolarHBondContact O-N 3.34Å; R359-L363 PolarHBondContact O-N 3.1Å; R359-Y410 HydrophobicContact CB-CD2 3.95Å
360	R	94.4	Very high	92.6	Very high	136 Å²	136	74.6 Å²	74.6	51%	0.513	35%	0.346	S	S	.	.	H	α-helix	trans	-53.9	-51.3	174.9	179.7	174.1	-177.6	-158	2.6	111.6	V356 R362 L363 V364 Y410 L447	V356-R360 WeakPolarHBondContact O-CB 3.2Å; V356-R360 PolarHBondContact O-N 3.23Å; R360-R362 VanDerWaalsContact C-N 3.31Å; R360-R362 PolarHBondContact O-N 2.92Å; R360-L363 PolarHBondContact O-N 2.99Å; R360-V364 WeakPolarHBondContact O-CG2 3.41Å; R360-V364 PolarHBondContact O-N 3.2Å; R360-Y410 HydrophobicContact CB-CD2 4.31Å; R360-Y410 HydrophobicContact CB-CE2 3.9Å; R360-L447 HydrophobicContact CG-CD1 4.31Å; R360-L447 HydrophobicContact CG-CD2 3.88Å
361	A	94.9	Very high	92.9	Very high	56 Å²	56	73.1 Å²	73.1	46%	0.463	33%	0.332	S	S	.	.	H	α-helix	trans	-59.1	-41	179.3	0	0	0	0	0	112.7	K357 R359 V364 V365	K357-A361 PolarHBondContact O-N 2.82Å; R359-A361 PolarHBondContact O-N 3.17Å; A361-V364 PolarHBondContact O-N 2.85Å; A361-V365 WeakPolarHBondContact O-CG2 3.37Å; A361-V365 PolarHBondContact O-N 2.89Å
362	R	95.3	Very high	93.1	Very high	136 Å²	136	72.2 Å²	72.2	51%	0.513	33%	0.329	S	S	.	.	H	α-helix	trans	-67.9	-36.9	176.6	-71.4	172.7	173.8	-153.2	-7.7	113.1	K358 R359 R360 A366	K358-R362 WeakPolarHBondContact O-CG 3.45Å; K358-R362 PolarHBondContact O-N 3.28Å; R359-R362 PolarHBondContact O-N 3.34Å; R360-R362 VanDerWaalsContact C-N 3.31Å; R360-R362 PolarHBondContact O-N 2.92Å; R362-A366 WeakPolarHBondContact O-CB 3.43Å; R362-A366 PolarHBondContact O-N 3.31Å; R362-A366 VanDerWaalsContact O-N 3.1Å
363	L	95.4	Very high	93.3	Very high	0 Å²	0	75.6 Å²	75.6	0%	0	34%	0.344	C	S	.	.	H	α-helix	trans	-66.8	-44	175.6	173.1	57.8	0	0	0	111.3	R359 R360 V365 A366 V367 A406 L407 Y410 L443 L447	R359-L363 PolarHBondContact O-N 3.1Å; R360-L363 PolarHBondContact O-N 2.99Å; L363-V365 PolarHBondContact O-N 2.75Å; L363-A366 PolarHBondContact O-N 2.91Å; L363-V367 HydrophobicContact CD1-CG2 3.82Å; L363-V367 WeakPolarHBondContact O-CG2 3.43Å; L363-V367 PolarHBondContact O-N 3.24Å; L363-A406 HydrophobicContact CB-CB 4.48Å; L363-A406 HydrophobicContact CD1-CB 4.3Å; L363-L407 HydrophobicContact CD1-CB 3.82Å; L363-L407 HydrophobicContact CD1-CD1 4.06Å; L363-L407 HydrophobicContact CD2-CD1 3.81Å; L363-Y410 HydrophobicContact CD2-CD1 3.76Å; L363-Y410 HydrophobicContact CD2-CG 3.8Å; L363-L443 HydrophobicContact CD1-CD2 4.05Å; L363-L443 HydrophobicContact CD2-CD2 3.97Å; L363-L443 HydrophobicContact CG-CD2 3.66Å; L363-L447 HydrophobicContact CD2-CD2 4.02Å
364	V	95.8	Very high	93.1	Very high	34 Å²	34	71.4 Å²	71.4	21%	0.206	33%	0.325	C	S	.	.	H	α-helix	trans	-56	-52.6	176.1	172.1	0	0	0	0	110.8	R360 A361 A366 V367 E368 L443 L447	R360-V364 WeakPolarHBondContact O-CG2 3.41Å; R360-V364 PolarHBondContact O-N 3.2Å; A361-V364 PolarHBondContact O-N 2.85Å; V364-A366 PolarHBondContact O-N 2.85Å; V364-V367 PolarHBondContact O-N 3.5Å; V364-E368 HydrophobicContact CG1-CG 4.42Å; V364-E368 WeakPolarHBondContact O-CB 3.41Å; V364-E368 WeakPolarHBondContact O-CG 3.45Å; V364-E368 PolarHBondContact O-N 2.95Å; V364-L443 HydrophobicContact CB-CD1 4.38Å; V364-L443 HydrophobicContact CG2-CD1 4.05Å; V364-L447 HydrophobicContact CG2-CD1 4.08Å
365	V	95.9	Very high	92.8	Very high	71 Å²	71	68 Å²	68	43%	0.43	32%	0.318	S	S	.	.	H	α-helix	trans	-60.5	-47.3	180	174.3	0	0	0	0	111.9	A361 L363 V367 E368 E369	A361-V365 WeakPolarHBondContact O-CG2 3.37Å; A361-V365 PolarHBondContact O-N 2.89Å; L363-V365 PolarHBondContact O-N 2.75Å; V365-V367 VanDerWaalsContact C-N 3.29Å; V365-V367 PolarHBondContact O-N 3.02Å; V365-E368 PolarHBondContact O-N 3.47Å; V365-E369 HydrophobicContact CG1-CG 4.35Å; V365-E369 WeakPolarHBondContact CG1-OE1 3.32Å; V365-E369 WeakPolarHBondContact O-CG 3.49Å; V365-E369 PolarHBondContact O-N 3.27Å
366	A	95.3	Very high	92.5	Very high	14 Å²	14	71 Å²	71	12%	0.116	33%	0.329	C	S	.	.	H	α-helix	trans	-63	-33.6	-178.7	0	0	0	0	0	113.2	R362 L363 V364 A370 A406	R362-A366 WeakPolarHBondContact O-CB 3.43Å; R362-A366 PolarHBondContact O-N 3.31Å; R362-A366 VanDerWaalsContact O-N 3.1Å; L363-A366 PolarHBondContact O-N 2.91Å; V364-A366 PolarHBondContact O-N 2.85Å; A366-A370 WeakPolarHBondContact O-CB 3.42Å; A366-A370 PolarHBondContact O-N 3.45Å; A366-A370 VanDerWaalsContact O-N 3.13Å; A366-A406 HydrophobicContact CB-CB 3.93Å
367	V	95.4	Very high	91.9	Very high	0 Å²	0	71.8 Å²	71.8	0%	0	33%	0.332	C	S	.	.	H	α-helix	trans	-77.9	-37.9	175.5	177.4	0	0	0	0	111.5	L363 V364 V365 A370 F371 M403 P439 F442 L443	L363-V367 HydrophobicContact CD1-CG2 3.82Å; L363-V367 WeakPolarHBondContact O-CG2 3.43Å; L363-V367 PolarHBondContact O-N 3.24Å; V364-V367 PolarHBondContact O-N 3.5Å; V365-V367 VanDerWaalsContact C-N 3.29Å; V365-V367 PolarHBondContact O-N 3.02Å; V367-A370 PolarHBondContact O-N 3.32Å; V367-F371 HydrophobicContact CG1-CD2 3.67Å; V367-F371 HydrophobicContact CG1-CE2 3.67Å; V367-F371 VanDerWaalsContact O-CD2 3.32Å; V367-F371 WeakPolarHBondContact O-CD2 3.47Å; V367-F371 PolarHBondContact O-N 2.93Å; V367-M403 HydrophobicContact CG1-CE 4.28Å; V367-M403 HydrophobicContact CG2-CB 4Å; V367-M403 HydrophobicContact CG2-CE 4.15Å; V367-M403 HydrophobicContact CG2-SD 3.95Å; V367-P439 HydrophobicContact CG1-CB 4.07Å; V367-F442 HydrophobicContact CG1-CD1 3.74Å; V367-F442 HydrophobicContact CG1-CE1 4.3Å; V367-F442 HydrophobicContact CG2-CD1 4.34Å; V367-F442 HydrophobicContact CG2-CE1 4.17Å; V367-L443 HydrophobicContact CB-CD1 4.18Å; V367-L443 HydrophobicContact CB-CD2 4.3Å; V367-L443 HydrophobicContact CB-CG 4.29Å; V367-L443 HydrophobicContact CG1-CD1 4.32Å; V367-L443 HydrophobicContact CG1-CG 4.15Å; V367-L443 HydrophobicContact CG2-CD2 3.87Å; V367-L443 HydrophobicContact CG2-CG 4.37Å
368	E	94.8	Very high	91.1	Very high	65 Å²	65	69.3 Å²	69.3	30%	0.304	32%	0.322	S	S	.	.	H	α-helix	trans	-60.7	-44.2	173.6	-74	175.5	163.1	0	0	111.1	V364 V365 F371 I372 P439	V364-E368 HydrophobicContact CG1-CG 4.42Å; V364-E368 WeakPolarHBondContact O-CB 3.41Å; V364-E368 WeakPolarHBondContact O-CG 3.45Å; V364-E368 PolarHBondContact O-N 2.95Å; V365-E368 PolarHBondContact O-N 3.47Å; E368-F371 PolarHBondContact O-N 2.81Å; E368-I372 WeakPolarHBondContact O-CD1 3.05Å; E368-I372 VanDerWaalsContact O-CG1 3.26Å; E368-I372 WeakPolarHBondContact O-CG1 3.44Å; E368-I372 PolarHBondContact O-N 3.36Å; E368-I372 VanDerWaalsContact O-N 3.07Å; E368-P439 HydrophobicContact CG-CB 3.85Å; E368-P439 HydrophobicContact CG-CG 4.18Å
369	E	94.2	Very high	90.3	Very high	128 Å²	128	65.8 Å²	65.8	60%	0.598	32%	0.316	S	S	*	.	H	α-helix	trans	-60.9	-45	173.5	-72.3	172.8	172.6	0	0	112.5	V365 I372 H373	V365-E369 HydrophobicContact CG1-CG 4.35Å; V365-E369 WeakPolarHBondContact CG1-OE1 3.32Å; V365-E369 WeakPolarHBondContact O-CG 3.49Å; V365-E369 PolarHBondContact O-N 3.27Å; E369-I372 PolarHBondContact O-N 3.3Å; E369-H373 PolarHBondContact O-N 2.86Å
370	A	92.3	Very high	89.5	Confident	3 Å²	3	67 Å²	67	3%	0.025	33%	0.325	C	S	.	.	H	α-helix	trans	-64.6	-39.5	179.4	0	0	0	0	0	113.3	A366 V367 H373 I374 I399 S402 M403	A366-A370 WeakPolarHBondContact O-CB 3.42Å; A366-A370 PolarHBondContact O-N 3.45Å; A366-A370 VanDerWaalsContact O-N 3.13Å; V367-A370 PolarHBondContact O-N 3.32Å; A370-H373 VanDerWaalsContact O-CB 3.26Å; A370-H373 WeakPolarHBondContact O-CB 3.41Å; A370-H373 PolarHBondContact O-N 3.36Å; A370-I374 PolarHBondContact O-N 3.46Å; A370-I374 VanDerWaalsContact O-N 3.15Å; A370-I399 HydrophobicContact CB-CB 4.43Å; A370-I399 HydrophobicContact CB-CD1 4.21Å; A370-S402 WeakPolarHBondContact CB-OG 3.42Å; A370-M403 HydrophobicContact CB-CE 3.41Å; A370-M403 VanDerWaalsContact CB-CE 3.41Å
371	F	91.8	Very high	88.3	Confident	10 Å²	10	63 Å²	63	4%	0.044	31%	0.313	C	S	.	.	H	α-helix	trans	-72.2	-32.7	176.5	-88.7	-111.2	0	0	0	112.5	V367 E368 H373 I374 Q375 M403 L429 C432 M437 P439 F442	V367-F371 HydrophobicContact CG1-CD2 3.67Å; V367-F371 HydrophobicContact CG1-CE2 3.67Å; V367-F371 VanDerWaalsContact O-CD2 3.32Å; V367-F371 WeakPolarHBondContact O-CD2 3.47Å; V367-F371 PolarHBondContact O-N 2.93Å; E368-F371 PolarHBondContact O-N 2.81Å; F371-H373 PolarHBondContact O-N 3.1Å; F371-I374 HydrophobicContact CD1-CD1 4.22Å; F371-I374 HydrophobicContact CD2-CD1 4.4Å; F371-I374 HydrophobicContact CG-CD1 4.16Å; F371-I374 PolarHBondContact O-N 3.37Å; F371-Q375 WeakPolarHBondContact O-CG 3.39Å; F371-Q375 PolarHBondContact O-N 3.18Å; F371-M403 HydrophobicContact CE2-CE 4.4Å; F371-L429 HydrophobicContact CE2-CD1 3.68Å; F371-L429 HydrophobicContact CZ-CD1 3.8Å; F371-C432 HydrophobicContact CZ-CB 4.27Å; F371-M437 WeakPolarHBondContact CE1-O 3.27Å; F371-P439 HydrophobicContact CB-CG 3.67Å; F371-P439 HydrophobicContact CD1-CG 4.13Å; F371-P439 HydrophobicContact CD2-CB 4.46Å; F371-P439 HydrophobicContact CD2-CG 4.4Å; F371-P439 HydrophobicContact CG-CB 4.35Å; F371-P439 HydrophobicContact CG-CG 3.82Å; F371-F442 HydrophobicContact CE2-CB 4.13Å; F371-F442 HydrophobicContact CE2-CD1 4.41Å; F371-F442 HydrophobicContact CE2-CG 4.23Å; F371-F442 HydrophobicContact CZ-CB 3.79Å; F371-F442 HydrophobicContact CZ-CG 4.21Å
372	I	90.8	Very high	86.9	Confident	76 Å²	76	68.3 Å²	68.3	39%	0.39	33%	0.328	S	S	.	.	H	α-helix	trans	-62	-35.1	169.3	-70.1	164.1	0	0	0	110.4	E368 E369 Q375 R376	E368-I372 WeakPolarHBondContact O-CD1 3.05Å; E368-I372 VanDerWaalsContact O-CG1 3.26Å; E368-I372 WeakPolarHBondContact O-CG1 3.44Å; E368-I372 PolarHBondContact O-N 3.36Å; E368-I372 VanDerWaalsContact O-N 3.07Å; E369-I372 PolarHBondContact O-N 3.3Å; I372-Q375 PolarHBondContact O-N 3.08Å; I372-R376 WeakPolarHBondContact O-CG 3.33Å; I372-R376 PolarHBondContact O-N 3.18Å; I372-R376 VanDerWaalsContact O-N 3.12Å
373	H	88.6	Confident	85.5	Confident	105 Å²	105	70.1 Å²	70.1	49%	0.486	34%	0.342	S	S	.	.	H	α-helix	trans	-63.7	-44.2	173.3	-165.8	-88.5	0	0	0	112.1	E369 A370 F371 Q375 R376 L377	E369-H373 PolarHBondContact O-N 2.86Å; A370-H373 VanDerWaalsContact O-CB 3.26Å; A370-H373 WeakPolarHBondContact O-CB 3.41Å; A370-H373 PolarHBondContact O-N 3.36Å; F371-H373 PolarHBondContact O-N 3.1Å; H373-Q375 PolarHBondContact O-N 3.19Å; H373-R376 PolarHBondContact O-N 3.2Å; H373-L377 WeakPolarHBondContact O-CG 3.48Å; H373-L377 PolarHBondContact O-N 3.46Å
374	I	85.1	Confident	83.8	Confident	10 Å²	10	77.4 Å²	77.4	5%	0.051	37%	0.374	C	S	.	.	H	α-helix	trans	-58	-48.3	173.8	-54.6	165.2	0	0	0	110.9	A370 F371 R376 L377 Q378 I399 I433	A370-I374 PolarHBondContact O-N 3.46Å; A370-I374 VanDerWaalsContact O-N 3.15Å; F371-I374 HydrophobicContact CD1-CD1 4.22Å; F371-I374 HydrophobicContact CD2-CD1 4.4Å; F371-I374 HydrophobicContact CG-CD1 4.16Å; F371-I374 PolarHBondContact O-N 3.37Å; I374-R376 PolarHBondContact O-N 2.87Å; I374-L377 PolarHBondContact O-N 3.44Å; I374-L377 VanDerWaalsContact O-N 3.17Å; I374-Q378 HydrophobicContact CG2-CG 4.05Å; I374-Q378 WeakPolarHBondContact O-CB 3.32Å; I374-Q378 WeakPolarHBondContact O-CG 3.39Å; I374-Q378 PolarHBondContact O-N 2.89Å; I374-I399 HydrophobicContact CD1-CD1 3.31Å; I374-I399 HydrophobicContact CD1-CG1 4.4Å; I374-I399 HydrophobicContact CG1-CD1 3.68Å; I374-I399 HydrophobicContact CG1-CG1 4.42Å; I374-I399 HydrophobicContact CG1-CG2 3.88Å; I374-I433 HydrophobicContact CD1-CD1 3.81Å; I374-I433 HydrophobicContact CD1-CG1 3.7Å
375	Q	83.9	Confident	82	Confident	124 Å²	124	80.6 Å²	80.6	58%	0.579	40%	0.398	S	S	*	.	H	α-helix	trans	-61.3	-32.7	-177.8	-72.9	178.6	-12.1	0	0	112.5	F371 I372 H373 A379	F371-Q375 WeakPolarHBondContact O-CG 3.39Å; F371-Q375 PolarHBondContact O-N 3.18Å; I372-Q375 PolarHBondContact O-N 3.08Å; H373-Q375 PolarHBondContact O-N 3.19Å; Q375-A379 WeakPolarHBondContact O-CB 3.38Å; Q375-A379 PolarHBondContact O-N 2.62Å; Q375-A379 VanDerWaalsContact O-N 3.14Å
376	R	84.1	Confident	80	Confident	158 Å²	158	83.9 Å²	83.9	60%	0.596	42%	0.42	S	S	*	.	H	α-helix	trans	-70.4	-48.9	173	-70.4	172.8	-174.3	174.9	2.8	111.7	I372 H373 I374 Q378 A379 E380	I372-R376 WeakPolarHBondContact O-CG 3.33Å; I372-R376 PolarHBondContact O-N 3.18Å; I372-R376 VanDerWaalsContact O-N 3.12Å; H373-R376 PolarHBondContact O-N 3.2Å; I374-R376 PolarHBondContact O-N 2.87Å; R376-Q378 VanDerWaalsContact C-N 3.32Å; R376-Q378 PolarHBondContact O-N 2.89Å; R376-A379 PolarHBondContact O-N 2.88Å; R376-A379 VanDerWaalsContact O-N 3.1Å; R376-E380 WeakPolarHBondContact O-CG 3.31Å; R376-E380 PolarHBondContact O-N 3.41Å
377	L	79.9	Confident	78.1	Confident	46 Å²	46	86.8 Å²	86.8	24%	0.241	45%	0.452	C	S	.	.	H	α-helix	trans	-56.3	-45.9	175.9	-69.8	174.6	0	0	0	111.6	H373 I374 A379 E380 E381	H373-L377 WeakPolarHBondContact O-CG 3.48Å; H373-L377 PolarHBondContact O-N 3.46Å; I374-L377 PolarHBondContact O-N 3.44Å; I374-L377 VanDerWaalsContact O-N 3.17Å; L377-A379 VanDerWaalsContact C-N 3.33Å; L377-A379 PolarHBondContact O-N 3.41Å; L377-E380 PolarHBondContact O-N 2.94Å; L377-E381 WeakPolarHBondContact O-CB 3.32Å; L377-E381 WeakPolarHBondContact O-CG 3.47Å; L377-E381 PolarHBondContact O-N 3.38Å
378	Q	76.7	Confident	76.3	Confident	75 Å²	75	95.3 Å²	95.3	35%	0.35	49%	0.492	S	S	.	.	H	α-helix	trans	-63	-36	176.9	-72.5	179.1	-26.9	0	0	112.9	I374 R376 Q382	I374-Q378 HydrophobicContact CG2-CG 4.05Å; I374-Q378 WeakPolarHBondContact O-CB 3.32Å; I374-Q378 WeakPolarHBondContact O-CG 3.39Å; I374-Q378 PolarHBondContact O-N 2.89Å; R376-Q378 VanDerWaalsContact C-N 3.32Å; R376-Q378 PolarHBondContact O-N 2.89Å; Q378-Q382 WeakPolarHBondContact O-CB 3.46Å; Q378-Q382 VanDerWaalsContact O-CG 3.22Å; Q378-Q382 WeakPolarHBondContact O-CG 3.34Å; Q378-Q382 PolarHBondContact O-N 2.91Å
379	A	79	Confident	74.8	Confident	50 Å²	50	98.7 Å²	98.7	41%	0.413	52%	0.516	S	S	.	.	H	α-helix	trans	-71.9	-34.7	175.1	0	0	0	0	0	112.6	Q375 R376 L377	Q375-A379 WeakPolarHBondContact O-CB 3.38Å; Q375-A379 PolarHBondContact O-N 2.62Å; Q375-A379 VanDerWaalsContact O-N 3.14Å; R376-A379 PolarHBondContact O-N 2.88Å; R376-A379 VanDerWaalsContact O-N 3.1Å; L377-A379 VanDerWaalsContact C-N 3.33Å; L377-A379 PolarHBondContact O-N 3.41Å
380	E	76.8	Confident	73.5	Confident	109 Å²	109	95 Å²	95	51%	0.509	50%	0.5	S	S	.	.	H	α-helix	trans	-72	-35.1	174.5	-71.1	170.9	-156.2	0	0	112	R376 L377 Q383	R376-E380 WeakPolarHBondContact O-CG 3.31Å; R376-E380 PolarHBondContact O-N 3.41Å; L377-E380 PolarHBondContact O-N 2.94Å; E380-Q383 PolarHBondContact O-N 3.07Å
381	E	68.9	Low	73.1	Confident	53 Å²	53	99 Å²	99	25%	0.248	52%	0.521	C	S	.	.	H	α-helix	trans	-70.4	-37.6	173.4	-76.8	175.6	-178.4	0	0	112.5	L377 Q383 K384 M390	L377-E381 WeakPolarHBondContact O-CB 3.32Å; L377-E381 WeakPolarHBondContact O-CG 3.47Å; L377-E381 PolarHBondContact O-N 3.38Å; E381-Q383 PolarHBondContact O-N 3.23Å; E381-Q383 VanDerWaalsContact O-N 3.15Å; E381-K384 PolarHBondContact O-N 3.3Å; E381-M390 WeakPolarHBondContact OE1-CE 3.28Å
382	Q	64.4	Low	72.7	Confident	167 Å²	167	100.2 Å²	100.2	78%	0.78	53%	0.53	S	S	*	.	T	Hydrogen-bonded Turn	trans	-62.9	-16.6	173	-77.1	171.6	19.1	0	0	113.7	Q378	Q378-Q382 WeakPolarHBondContact O-CB 3.46Å; Q378-Q382 VanDerWaalsContact O-CG 3.22Å; Q378-Q382 WeakPolarHBondContact O-CG 3.34Å; Q378-Q382 PolarHBondContact O-N 2.91Å
383	Q	65.9	Low	72.5	Confident	175 Å²	175	102.6 Å²	102.6	82%	0.818	53%	0.534	S	S	*	.	T	Hydrogen-bonded Turn	trans	-89.5	-7.9	171.6	-70.8	-174.6	-11.6	0	0	113.8	E380 E381	E380-Q383 PolarHBondContact O-N 3.07Å; E381-Q383 PolarHBondContact O-N 3.23Å; E381-Q383 VanDerWaalsContact O-N 3.15Å
384	K	61	Low	72.5	Confident	152 Å²	152	103 Å²	103	66%	0.661	54%	0.536	S	S	*	.	S	Bend	trans	-95.8	163.9	177.5	-69.3	175.8	-176.7	169.4	0	111.5	E381	E381-K384 PolarHBondContact O-N 3.3Å
385	S	56.1	Low	72.6	Confident	102 Å²	102	102.9 Å²	102.9	71%	0.713	54%	0.537	S	S	*	.			trans	-61.1	144.9	180	47.1	0	0	0	0	112.3	G387	S385-G387 PolarHBondContact O-N 2.78Å
386	P	54.3	Low	72.9	Confident	139 Å²	139	97 Å²	97	90%	0.903	51%	0.509	S	S	*	.	T	Hydrogen-bonded Turn	trans	-78.1	43.1	-163.4	34.1	-40	0	0	0	115.1
387	G	55.9	Low	73.2	Confident	76 Å²	76	94.9 Å²	94.9	78%	0.784	51%	0.506	S	S	*	.	T	Hydrogen-bonded Turn	trans	-109.2	-17.7	-176.4	0	0	0	0	0	115.7	S385	S385-G387 PolarHBondContact O-N 2.78Å
388	E	57.5	Low	73.6	Confident	179 Å²	179	95.9 Å²	95.9	84%	0.836	52%	0.521	S	S	*	.			trans	-141.5	82.8	-168.6	-162.8	165.5	-140.8	0	0	109.8
389	V	63.6	Low	74.2	Confident	135 Å²	135	92.6 Å²	92.6	82%	0.818	51%	0.506	S	S	*	.	P	Polyproline II helix	trans	-87.4	119.7	170.7	-180	0	0	0	0	107.2	D391	V389-D391 PolarHBondContact O-N 3.19Å
390	M	67.1	Low	74.8	Confident	51 Å²	51	90.9 Å²	90.9	25%	0.251	49%	0.489	S	S	.	.	P	Polyproline II helix	trans	-57.5	134.3	-178.8	-176.1	-177.8	-72.8	0	0	111.5	E381 E394 A395	E381-M390 WeakPolarHBondContact OE1-CE 3.28Å; M390-E394 HydrophobicContact CG-CB 4.11Å; M390-E394 HydrophobicContact CG-CG 4.14Å; M390-A395 HydrophobicContact CG-CB 4.19Å; M390-A395 WeakPolarHBondContact SD-CA 3.47Å; M390-A395 HydrophobicContact SD-CB 3.59Å; M390-A395 VanDerWaalsContact SD-CB 3.59Å
391	D	82.8	Confident	75.5	Confident	86 Å²	86	90.2 Å²	90.2	46%	0.46	49%	0.494	S	S	.	.	P	Polyproline II helix	trans	-65.7	133.7	176.4	179.3	57.1	0	0	0	110.2	V389 R393 E394 A395	V389-D391 PolarHBondContact O-N 3.19Å; D391-R393 PolarHBondContact O-N 2.79Å; D391-R393 WeakPolarHBondContact OD2-CB 3.34Å; D391-R393 PolarHBondContact OD2-N 3.02Å; D391-R393 VanDerWaalsContact OD2-N 3.17Å; D391-E394 HydrophobicContact CB-CB 4.28Å; D391-E394 WeakPolarHBondContact O-CA 3.34Å; D391-E394 WeakPolarHBondContact O-CB 3.39Å; D391-E394 PolarHBondContact O-N 3.48Å; D391-A395 PolarHBondContact O-N 3.24Å
392	P	84.4	Confident	76.5	Confident	37 Å²	37	91.2 Å²	91.2	24%	0.24	51%	0.507	C	S	.	.	H	α-helix	trans	-57.4	-21.5	-179.6	-30.4	37.4	0	0	0	115.3	A396 A430 I433 T434	P392-A396 WeakPolarHBondContact O-CB 3.47Å; P392-A396 PolarHBondContact O-N 2.91Å; P392-A396 VanDerWaalsContact O-N 3.16Å; P392-A430 WeakPolarHBondContact O-CB 3.37Å; P392-I433 HydrophobicContact CB-CB 4.5Å; P392-I433 HydrophobicContact CB-CG2 4.24Å; P392-T434 VanDerWaalsContact CB-OG1 3.28Å; P392-T434 WeakPolarHBondContact CB-OG1 3.32Å; P392-T434 WeakPolarHBondContact CG-OG1 3.26Å
393	R	87.4	Confident	77.9	Confident	126 Å²	126	83.3 Å²	83.3	48%	0.475	47%	0.47	S	S	.	.	H	α-helix	trans	-76.5	-39	171.3	-60.9	177.1	160.4	-121.5	-3.9	112.2	D391 A396 Q397 E423 A430	D391-R393 PolarHBondContact O-N 2.79Å; D391-R393 WeakPolarHBondContact OD2-CB 3.34Å; D391-R393 PolarHBondContact OD2-N 3.02Å; D391-R393 VanDerWaalsContact OD2-N 3.17Å; R393-A396 WeakPolarHBondContact O-CB 3.46Å; R393-A396 PolarHBondContact O-N 3.26Å; R393-Q397 WeakPolarHBondContact O-CG 3.38Å; R393-Q397 PolarHBondContact O-N 3.14Å; R393-E423 IonicContact NH1-OE1 2.61Å; R393-E423 PolarHBondContact NH1-OE1 2.88Å; R393-A430 HydrophobicContact CG-CB 4.03Å
394	E	88.4	Confident	79	Confident	112 Å²	112	75.3 Å²	75.3	52%	0.523	43%	0.434	S	S	.	.	H	α-helix	trans	-62.6	-46.4	174.1	-176.2	175.6	-161.2	0	0	110.5	M390 D391 A396 Q397 A398	M390-E394 HydrophobicContact CG-CB 4.11Å; M390-E394 HydrophobicContact CG-CG 4.14Å; D391-E394 HydrophobicContact CB-CB 4.28Å; D391-E394 WeakPolarHBondContact O-CA 3.34Å; D391-E394 WeakPolarHBondContact O-CB 3.39Å; D391-E394 PolarHBondContact O-N 3.48Å; E394-A396 VanDerWaalsContact C-N 3.3Å; E394-A396 PolarHBondContact O-N 3.36Å; E394-Q397 PolarHBondContact O-N 3.48Å; E394-Q397 VanDerWaalsContact O-N 3.15Å; E394-A398 WeakPolarHBondContact O-CB 3.5Å; E394-A398 PolarHBondContact O-N 3.03Å
395	A	86.9	Confident	80.5	Confident	9 Å²	9	75.6 Å²	75.6	7%	0.074	43%	0.431	C	S	.	.	H	α-helix	trans	-55.8	-44.2	173.2	0	0	0	0	0	112.1	M390 D391 A398 I399 I433	M390-A395 HydrophobicContact CG-CB 4.19Å; M390-A395 WeakPolarHBondContact SD-CA 3.47Å; M390-A395 HydrophobicContact SD-CB 3.59Å; M390-A395 VanDerWaalsContact SD-CB 3.59Å; D391-A395 PolarHBondContact O-N 3.24Å; A395-A398 PolarHBondContact O-N 3.49Å; A395-I399 WeakPolarHBondContact O-CG1 3.44Å; A395-I399 PolarHBondContact O-N 3.46Å; A395-I433 HydrophobicContact CB-CD1 4Å; A395-I433 HydrophobicContact CB-CG2 4.42Å
396	A	89.6	Confident	82.2	Confident	0 Å²	0	71.7 Å²	71.7	0%	0	41%	0.405	C	S	.	.	H	α-helix	trans	-63.5	-44	176.2	0	0	0	0	0	112.6	P392 R393 E394 F400 L429 A430 I433	P392-A396 WeakPolarHBondContact O-CB 3.47Å; P392-A396 PolarHBondContact O-N 2.91Å; P392-A396 VanDerWaalsContact O-N 3.16Å; R393-A396 WeakPolarHBondContact O-CB 3.46Å; R393-A396 PolarHBondContact O-N 3.26Å; E394-A396 VanDerWaalsContact C-N 3.3Å; E394-A396 PolarHBondContact O-N 3.36Å; A396-F400 VanDerWaalsContact O-CB 3.26Å; A396-F400 WeakPolarHBondContact O-CB 3.23Å; A396-F400 PolarHBondContact O-N 2.69Å; A396-L429 HydrophobicContact CB-CB 4Å; A396-L429 HydrophobicContact CB-CD2 3.94Å; A396-L429 HydrophobicContact CB-CG 3.78Å; A396-A430 HydrophobicContact CB-CB 4.07Å; A396-I433 HydrophobicContact CB-CD1 3.97Å
397	Q	90.6	Very high	84	Confident	114 Å²	114	65.1 Å²	65.1	53%	0.533	36%	0.362	S	S	.	.	H	α-helix	trans	-64.4	-40.8	177.9	-74.5	175.9	1.1	0	0	112.1	R393 E394 I399 P401 L426	R393-Q397 WeakPolarHBondContact O-CG 3.38Å; R393-Q397 PolarHBondContact O-N 3.14Å; E394-Q397 PolarHBondContact O-N 3.48Å; E394-Q397 VanDerWaalsContact O-N 3.15Å; Q397-I399 PolarHBondContact O-N 3.34Å; Q397-P401 VanDerWaalsContact O-CD 3.22Å; Q397-P401 WeakPolarHBondContact O-CD 3.34Å; Q397-L426 HydrophobicContact CG-CD1 4.19Å; Q397-L426 HydrophobicContact CG-CD2 4.19Å
398	A	88.5	Confident	85.7	Confident	67 Å²	67	62.7 Å²	62.7	55%	0.554	33%	0.331	S	S	*	.	H	α-helix	trans	-61.9	-41.4	179.5	0	0	0	0	0	112.7	E394 A395	E394-A398 WeakPolarHBondContact O-CB 3.5Å; E394-A398 PolarHBondContact O-N 3.03Å; A395-A398 PolarHBondContact O-N 3.49Å
399	I	89.3	Confident	87.3	Confident	6 Å²	6	56.6 Å²	56.6	3%	0.031	30%	0.301	C	S	.	.	H	α-helix	trans	-88.3	-24.4	-178	67	157.3	0	0	0	114.3	A370 I374 A395 Q397 P401 S402 M403 L429	A370-I399 HydrophobicContact CB-CB 4.43Å; A370-I399 HydrophobicContact CB-CD1 4.21Å; I374-I399 HydrophobicContact CD1-CD1 3.31Å; I374-I399 HydrophobicContact CD1-CG1 4.4Å; I374-I399 HydrophobicContact CG1-CD1 3.68Å; I374-I399 HydrophobicContact CG1-CG1 4.42Å; I374-I399 HydrophobicContact CG1-CG2 3.88Å; A395-I399 WeakPolarHBondContact O-CG1 3.44Å; A395-I399 PolarHBondContact O-N 3.46Å; Q397-I399 PolarHBondContact O-N 3.34Å; I399-P401 VanDerWaalsContact C-CD 3.44Å; I399-S402 WeakPolarHBondContact O-CB 3.43Å; I399-S402 PolarHBondContact O-N 3.25Å; I399-S402 PolarHBondContact O-OG 2.93Å; I399-M403 HydrophobicContact CD1-CE 3.8Å; I399-M403 HydrophobicContact CG1-CE 4.44Å; I399-L429 HydrophobicContact CD1-CD1 4.05Å; I399-L429 HydrophobicContact CD1-CD2 3.95Å; I399-L429 HydrophobicContact CD1-CG 4.32Å; I399-L429 HydrophobicContact CG1-CD2 3.94Å
400	F	91.8	Very high	88.6	Confident	14 Å²	14	50.9 Å²	50.9	6%	0.061	27%	0.265	C	S	.	.	H	α-helix	trans	-53	-42.1	-172.7	175.4	-110.3	0	0	0	114.2	A396 S402 M403 A404 M422 I425 L426 L429	A396-F400 VanDerWaalsContact O-CB 3.26Å; A396-F400 WeakPolarHBondContact O-CB 3.23Å; A396-F400 PolarHBondContact O-N 2.69Å; F400-S402 PolarHBondContact O-N 3Å; F400-S402 VanDerWaalsContact O-N 3.13Å; F400-M403 HydrophobicContact CD2-CG 4.32Å; F400-M403 VanDerWaalsContact O-CG 3.27Å; F400-M403 WeakPolarHBondContact O-CG 3.38Å; F400-M403 PolarHBondContact O-N 3.43Å; F400-M403 VanDerWaalsContact O-N 3.08Å; F400-A404 HydrophobicContact CD1-CB 4.17Å; F400-A404 HydrophobicContact CD2-CB 4.39Å; F400-A404 HydrophobicContact CE1-CB 3.8Å; F400-A404 HydrophobicContact CE2-CB 4.02Å; F400-A404 HydrophobicContact CG-CB 4.46Å; F400-A404 HydrophobicContact CZ-CB 3.72Å; F400-A404 VanDerWaalsContact O-CB 3.32Å; F400-A404 WeakPolarHBondContact O-CB 3.42Å; F400-A404 PolarHBondContact O-N 3.34Å; F400-M422 HydrophobicContact CD1-CE 4.03Å; F400-M422 HydrophobicContact CE1-CE 3.84Å; F400-M422 HydrophobicContact CE1-CG 3.87Å; F400-M422 HydrophobicContact CE1-SD 3.83Å; F400-M422 HydrophobicContact CZ-CG 4.18Å; F400-I425 HydrophobicContact CD2-CG2 4.13Å; F400-I425 HydrophobicContact CE2-CB 4.42Å; F400-I425 HydrophobicContact CE2-CG2 3.62Å; F400-L426 HydrophobicContact CB-CD2 3.64Å; F400-L426 HydrophobicContact CD1-CD2 4.1Å; F400-L426 HydrophobicContact CD2-CD2 4.28Å; F400-L426 HydrophobicContact CG-CD2 3.75Å; F400-L429 HydrophobicContact CB-CD2 4.33Å
401	P	92	Very high	89.7	Confident	94 Å²	94	48.7 Å²	48.7	61%	0.61	26%	0.255	S	S	*	.	H	α-helix	trans	-54.7	-32.1	177.1	-28.7	36.5	0	0	0	114.9	Q397 I399 M403	Q397-P401 VanDerWaalsContact O-CD 3.22Å; Q397-P401 WeakPolarHBondContact O-CD 3.34Å; I399-P401 VanDerWaalsContact C-CD 3.44Å; P401-M403 VanDerWaalsContact C-N 3.33Å; P401-M403 PolarHBondContact O-N 2.96Å
402	S	89.9	Confident	90	Very high	75 Å²	75	49.1 Å²	49.1	52%	0.524	25%	0.25	S	C	.	.	H	α-helix	trans	-66.3	-33.7	179.6	70.3	0	0	0	0	113	A370 I399 F400	A370-S402 WeakPolarHBondContact CB-OG 3.42Å; I399-S402 WeakPolarHBondContact O-CB 3.43Å; I399-S402 PolarHBondContact O-N 3.25Å; I399-S402 PolarHBondContact O-OG 2.93Å; F400-S402 PolarHBondContact O-N 3Å; F400-S402 VanDerWaalsContact O-N 3.13Å
403	M	92.3	Very high	90.1	Very high	0 Å²	0	48.9 Å²	48.9	0%	0	25%	0.248	C	C	.	.	H	α-helix	trans	-102.4	-23.4	-178.7	64.1	173.6	72.7	0	0	113.9	V367 A370 F371 I399 F400 P401 R405 A406 L407 L429 F442	V367-M403 HydrophobicContact CG1-CE 4.28Å; V367-M403 HydrophobicContact CG2-CB 4Å; V367-M403 HydrophobicContact CG2-CE 4.15Å; V367-M403 HydrophobicContact CG2-SD 3.95Å; A370-M403 HydrophobicContact CB-CE 3.41Å; A370-M403 VanDerWaalsContact CB-CE 3.41Å; F371-M403 HydrophobicContact CE2-CE 4.4Å; I399-M403 HydrophobicContact CD1-CE 3.8Å; I399-M403 HydrophobicContact CG1-CE 4.44Å; F400-M403 HydrophobicContact CD2-CG 4.32Å; F400-M403 VanDerWaalsContact O-CG 3.27Å; F400-M403 WeakPolarHBondContact O-CG 3.38Å; F400-M403 PolarHBondContact O-N 3.43Å; F400-M403 VanDerWaalsContact O-N 3.08Å; P401-M403 VanDerWaalsContact C-N 3.33Å; P401-M403 PolarHBondContact O-N 2.96Å; M403-R405 VanDerWaalsContact C-N 3.34Å; M403-R405 PolarHBondContact O-N 3.2Å; M403-A406 WeakPolarHBondContact O-CA 3.44Å; M403-A406 WeakPolarHBondContact O-CB 3.4Å; M403-A406 PolarHBondContact O-N 3.39Å; M403-L407 PolarHBondContact O-N 2.61Å; M403-L429 HydrophobicContact CE-CD1 4.35Å; M403-L429 HydrophobicContact CE-CD2 4.35Å; M403-L429 HydrophobicContact SD-CD2 4.28Å; M403-F442 HydrophobicContact SD-CE1 3.82Å; M403-F442 HydrophobicContact SD-CZ 4Å
404	A	90.6	Very high	90	Very high	8 Å²	8	43.6 Å²	43.6	7%	0.066	23%	0.23	C	C	.	.	H	α-helix	trans	-51	-48.5	-170.4	0	0	0	0	0	112.9	F400 A406 L407 Q408	F400-A404 HydrophobicContact CD1-CB 4.17Å; F400-A404 HydrophobicContact CD2-CB 4.39Å; F400-A404 HydrophobicContact CE1-CB 3.8Å; F400-A404 HydrophobicContact CE2-CB 4.02Å; F400-A404 HydrophobicContact CG-CB 4.46Å; F400-A404 HydrophobicContact CZ-CB 3.72Å; F400-A404 VanDerWaalsContact O-CB 3.32Å; F400-A404 WeakPolarHBondContact O-CB 3.42Å; F400-A404 PolarHBondContact O-N 3.34Å; A404-A406 VanDerWaalsContact C-N 3.3Å; A404-A406 PolarHBondContact O-N 2.8Å; A404-L407 PolarHBondContact O-N 2.77Å; A404-Q408 VanDerWaalsContact O-CB 3.28Å; A404-Q408 WeakPolarHBondContact O-CB 3.28Å; A404-Q408 PolarHBondContact O-N 2.88Å
405	R	91.3	Very high	89.8	Confident	157 Å²	157	42.2 Å²	42.2	59%	0.592	22%	0.219	S	C	*	.	H	α-helix	trans	-66.1	-28.8	179.8	-167.8	-179.1	-171.8	-133.4	10.3	113.5	M403 K409	M403-R405 VanDerWaalsContact C-N 3.34Å; M403-R405 PolarHBondContact O-N 3.2Å; R405-K409 HydrophobicContact CG-CD 4.37Å; R405-K409 WeakPolarHBondContact O-CB 3.37Å; R405-K409 VanDerWaalsContact O-CG 3.23Å; R405-K409 WeakPolarHBondContact O-CG 3.48Å; R405-K409 PolarHBondContact O-N 3.33Å
406	A	92.1	Very high	89.5	Confident	20 Å²	20	42.6 Å²	42.6	17%	0.165	22%	0.22	C	C	.	.	H	α-helix	trans	-75.8	-42.3	175.1	0	0	0	0	0	110.7	L363 A366 M403 A404 Y410	L363-A406 HydrophobicContact CB-CB 4.48Å; L363-A406 HydrophobicContact CD1-CB 4.3Å; A366-A406 HydrophobicContact CB-CB 3.93Å; M403-A406 WeakPolarHBondContact O-CA 3.44Å; M403-A406 WeakPolarHBondContact O-CB 3.4Å; M403-A406 PolarHBondContact O-N 3.39Å; A404-A406 VanDerWaalsContact C-N 3.3Å; A404-A406 PolarHBondContact O-N 2.8Å; A406-Y410 PolarHBondContact O-N 2.72Å
407	L	92.3	Very high	89.2	Confident	2 Å²	2	46.5 Å²	46.5	1%	0.01	24%	0.238	C	C	.	.	H	α-helix	trans	-66.1	-54.1	178.7	-177.9	60.1	0	0	0	111.6	L363 M403 A404 K409 Y410 L411 I425 Y446	L363-L407 HydrophobicContact CD1-CB 3.82Å; L363-L407 HydrophobicContact CD1-CD1 4.06Å; L363-L407 HydrophobicContact CD2-CD1 3.81Å; M403-L407 PolarHBondContact O-N 2.61Å; A404-L407 PolarHBondContact O-N 2.77Å; L407-K409 VanDerWaalsContact C-N 3.26Å; L407-K409 PolarHBondContact O-N 2.88Å; L407-Y410 CarbonylContact O-C 3.6Å; L407-Y410 WeakPolarHBondContact O-CA 3.48Å; L407-Y410 WeakPolarHBondContact O-CB 3.37Å; L407-Y410 PolarHBondContact O-N 3.02Å; L407-L411 HydrophobicContact CD1-CD1 4.1Å; L407-L411 HydrophobicContact CD1-CD2 4.49Å; L407-L411 HydrophobicContact CD1-CG 4.1Å; L407-L411 HydrophobicContact CG-CD1 3.99Å; L407-L411 HydrophobicContact CG-CG 4.36Å; L407-L411 WeakPolarHBondContact O-CG 3.46Å; L407-L411 PolarHBondContact O-N 3.05Å; L407-I425 HydrophobicContact CD2-CD1 3.98Å; L407-I425 HydrophobicContact CD2-CG1 4.39Å; L407-I425 HydrophobicContact CD2-CG2 3.78Å; L407-Y446 HydrophobicContact CD1-CD1 4.16Å; L407-Y446 HydrophobicContact CD1-CD2 4.24Å; L407-Y446 HydrophobicContact CD1-CG 3.93Å
408	Q	90.9	Very high	88.6	Confident	25 Å²	25	44.6 Å²	44.6	12%	0.117	23%	0.229	C	C	.	.	H	α-helix	trans	-56.4	-39.7	178.2	-165.3	-162.7	29.1	0	0	111.7	D72 N73 A404 R412	D72-Q408 PolarHBondContact O-NE2 3.08Å; N73-Q408 PolarHBondContact OD1-NE2 2.65Å; A404-Q408 VanDerWaalsContact O-CB 3.28Å; A404-Q408 WeakPolarHBondContact O-CB 3.28Å; A404-Q408 PolarHBondContact O-N 2.88Å; Q408-R412 VanDerWaalsContact NE2-NH2 3.19Å; Q408-R412 VanDerWaalsContact O-CB 3.32Å; Q408-R412 WeakPolarHBondContact O-CB 3.28Å; Q408-R412 WeakPolarHBondContact O-CG 3.38Å; Q408-R412 PolarHBondContact O-N 2.94Å
409	K	91.1	Very high	88.1	Confident	51 Å²	51	42.7 Å²	42.7	22%	0.222	21%	0.208	C	C	.	.	H	α-helix	trans	-72.7	-25.9	175.8	-72.3	-176.4	-177.6	-169.7	0	113.7	R405 L407 T413	R405-K409 HydrophobicContact CG-CD 4.37Å; R405-K409 WeakPolarHBondContact O-CB 3.37Å; R405-K409 VanDerWaalsContact O-CG 3.23Å; R405-K409 WeakPolarHBondContact O-CG 3.48Å; R405-K409 PolarHBondContact O-N 3.33Å; L407-K409 VanDerWaalsContact C-N 3.26Å; L407-K409 PolarHBondContact O-N 2.88Å; K409-T413 WeakPolarHBondContact O-CB 3.36Å; K409-T413 PolarHBondContact O-N 2.86Å; K409-T413 PolarHBondContact O-OG1 2.82Å
410	Y	92.1	Very high	87.8	Confident	14 Å²	14	42.9 Å²	42.9	6%	0.055	21%	0.208	C	C	.	.	H	α-helix	trans	-71.2	-56.5	169.3	178.7	-102.9	0	0	0	109.8	V356 R359 R360 L363 A406 L407 R412 T413 T414 Y446 L447	V356-Y410 HydrophobicContact CG1-CE2 4.04Å; R359-Y410 HydrophobicContact CB-CD2 3.95Å; R360-Y410 HydrophobicContact CB-CD2 4.31Å; R360-Y410 HydrophobicContact CB-CE2 3.9Å; L363-Y410 HydrophobicContact CD2-CD1 3.76Å; L363-Y410 HydrophobicContact CD2-CG 3.8Å; A406-Y410 PolarHBondContact O-N 2.72Å; L407-Y410 CarbonylContact O-C 3.6Å; L407-Y410 WeakPolarHBondContact O-CA 3.48Å; L407-Y410 WeakPolarHBondContact O-CB 3.37Å; L407-Y410 PolarHBondContact O-N 3.02Å; Y410-R412 PolarHBondContact O-N 3.15Å; Y410-T413 CarbonylContact O-C 3.6Å; Y410-T413 WeakPolarHBondContact O-CA 3.34Å; Y410-T413 WeakPolarHBondContact O-CB 3.33Å; Y410-T413 PolarHBondContact O-N 3.1Å; Y410-T414 HydrophobicContact CD2-CG2 4.37Å; Y410-T414 HydrophobicContact CE1-CG2 4.11Å; Y410-T414 HydrophobicContact CE2-CG2 3.86Å; Y410-T414 PolarHBondContact O-N 3.16Å; Y410-T414 PolarHBondContact O-OG1 2.9Å; Y410-T414 VanDerWaalsContact O-OG1 3.08Å; Y410-Y446 WeakPolarHBondContact CE1-O 3.49Å; Y410-L447 HydrophobicContact CD1-CD2 4.27Å; Y410-L447 HydrophobicContact CE1-CD2 3.66Å; Y410-L447 HydrophobicContact CE2-CD2 4.1Å
411	L	89.6	Confident	87.5	Confident	6 Å²	6	44.9 Å²	44.9	3%	0.031	22%	0.224	C	C	.	.	H	α-helix	trans	-56.2	-43	-179	-63.7	178.8	0	0	0	113.3	L407 T413 T414 R415 Q416 H420 Y446	L407-L411 HydrophobicContact CD1-CD1 4.1Å; L407-L411 HydrophobicContact CD1-CD2 4.49Å; L407-L411 HydrophobicContact CD1-CG 4.1Å; L407-L411 HydrophobicContact CG-CD1 3.99Å; L407-L411 HydrophobicContact CG-CG 4.36Å; L407-L411 WeakPolarHBondContact O-CG 3.46Å; L407-L411 PolarHBondContact O-N 3.05Å; L411-T413 VanDerWaalsContact C-N 3.32Å; L411-T413 PolarHBondContact O-N 3.29Å; L411-T414 WeakPolarHBondContact CA-OG1 3.44Å; L411-T414 CarbonylContact O-C 3.54Å; L411-T414 PolarHBondContact O-N 3.29Å; L411-T414 PolarHBondContact O-OG1 3.36Å; L411-R415 WeakPolarHBondContact O-CA 3.2Å; L411-R415 PolarHBondContact O-N 3.35Å; L411-Q416 HydrophobicContact CB-CB 4.5Å; L411-Q416 HydrophobicContact CD2-CB 3.84Å; L411-Q416 PolarHBondContact O-N 2.84Å; L411-H420 HydrophobicContact CD1-CB 4.09Å; L411-Y446 HydrophobicContact CD2-CD1 4.33Å
412	R	87.9	Confident	87.3	Confident	94 Å²	94	43 Å²	43	36%	0.355	21%	0.208	S	C	.	.	H	α-helix	trans	-64.2	-33.3	173.1	-75	176.3	172.3	168.6	-4.6	112.7	N73 E76 Q408 Y410	N73-R412 PolarHBondContact OD1-NH2 3.23Å; E76-R412 IonicContact OE1-CZ 3.76Å; E76-R412 IonicContact OE1-NH1 2.69Å; E76-R412 PolarHBondContact OE1-NH1 3.43Å; E76-R412 IonicContact OE2-NH1 3.22Å; Q408-R412 VanDerWaalsContact NE2-NH2 3.19Å; Q408-R412 VanDerWaalsContact O-CB 3.32Å; Q408-R412 WeakPolarHBondContact O-CB 3.28Å; Q408-R412 WeakPolarHBondContact O-CG 3.38Å; Q408-R412 PolarHBondContact O-N 2.94Å; Y410-R412 PolarHBondContact O-N 3.15Å
413	T	88	Confident	87.2	Confident	33 Å²	33	44.1 Å²	44.1	20%	0.202	21%	0.205	C	C	.	.	H	α-helix	trans	-74	-36.8	177.7	-54	0	0	0	0	111.1	H352 R355 V356 K409 Y410 L411 R415	H352-T413 PolarHBondContact CE1-O 2.61Å; R355-T413 HydrophobicContact CB-CG2 4.49Å; V356-T413 HydrophobicContact CG2-CG2 3.86Å; K409-T413 WeakPolarHBondContact O-CB 3.36Å; K409-T413 PolarHBondContact O-N 2.86Å; K409-T413 PolarHBondContact O-OG1 2.82Å; Y410-T413 CarbonylContact O-C 3.6Å; Y410-T413 WeakPolarHBondContact O-CA 3.34Å; Y410-T413 WeakPolarHBondContact O-CB 3.33Å; Y410-T413 PolarHBondContact O-N 3.1Å; L411-T413 VanDerWaalsContact C-N 3.32Å; L411-T413 PolarHBondContact O-N 3.29Å; T413-R415 VanDerWaalsContact C-N 3.34Å
414	T	85.8	Confident	87	Confident	15 Å²	15	45.3 Å²	45.3	9%	0.092	21%	0.213	C	C	.	.	H	α-helix	trans	-86.7	0.5	176.5	50.8	0	0	0	0	113.8	L296 V356 Y410 L411 Q416	L296-T414 WeakPolarHBondContact CD2-O 3.43Å; V356-T414 HydrophobicContact CG1-CG2 4.1Å; V356-T414 HydrophobicContact CG2-CG2 4.46Å; Y410-T414 HydrophobicContact CD2-CG2 4.37Å; Y410-T414 HydrophobicContact CE1-CG2 4.11Å; Y410-T414 HydrophobicContact CE2-CG2 3.86Å; Y410-T414 PolarHBondContact O-N 3.16Å; Y410-T414 PolarHBondContact O-OG1 2.9Å; Y410-T414 VanDerWaalsContact O-OG1 3.08Å; L411-T414 WeakPolarHBondContact CA-OG1 3.44Å; L411-T414 CarbonylContact O-C 3.54Å; L411-T414 PolarHBondContact O-N 3.29Å; L411-T414 PolarHBondContact O-OG1 3.36Å; T414-Q416 VanDerWaalsContact C-N 3.31Å; T414-Q416 VanDerWaalsContact CB-OE1 3.26Å; T414-Q416 PolarHBondContact O-N 2.76Å; T414-Q416 PolarHBondContact OG1-OE1 3.15Å
415	R	83	Confident	87	Confident	82 Å²	82	45.4 Å²	45.4	31%	0.309	21%	0.212	S	C	.	.	T	Hydrogen-bonded Turn	trans	54.7	42.6	-177.2	-63.6	-178.3	159.6	-150.8	-12.7	112.9	N293 N295 L296 L411 T413 H418	N293-R415 PolarHBondContact ND2-O 3.47Å; N295-R415 HydrophobicContact CB-CB 4.18Å; N295-R415 WeakPolarHBondContact O-CD 3.43Å; N295-R415 PolarHBondContact O-NH1 3.16Å; L296-R415 HydrophobicContact CD2-CB 4.37Å; L411-R415 WeakPolarHBondContact O-CA 3.2Å; L411-R415 PolarHBondContact O-N 3.35Å; T413-R415 VanDerWaalsContact C-N 3.34Å; R415-H418 PolarHBondContact O-CE1 3.31Å; R415-H418 VanDerWaalsContact O-CE1 3.28Å
416	Q	81.8	Confident	87	Confident	18 Å²	18	38.6 Å²	38.6	8%	0.084	19%	0.188	C	C	.	.			trans	-108.3	2.3	-178.5	-73.4	170.8	-47	0	0	113.5	L411 T414 H418 Y419 H420	L411-Q416 HydrophobicContact CB-CB 4.5Å; L411-Q416 HydrophobicContact CD2-CB 3.84Å; L411-Q416 PolarHBondContact O-N 2.84Å; T414-Q416 VanDerWaalsContact C-N 3.31Å; T414-Q416 VanDerWaalsContact CB-OE1 3.26Å; T414-Q416 PolarHBondContact O-N 2.76Å; T414-Q416 PolarHBondContact OG1-OE1 3.15Å; Q416-H418 VanDerWaalsContact C-N 3.29Å; Q416-H418 PolarHBondContact O-N 2.85Å; Q416-Y419 HydrophobicContact CB-CD2 4.23Å; Q416-Y419 HydrophobicContact CG-CD2 4.39Å; Q416-Y419 PolarHBondContact O-N 3.26Å; Q416-Y419 VanDerWaalsContact O-N 3.07Å; Q416-H420 PolarHBondContact O-CD2 3.3Å
417	Q	82.1	Confident	87	Confident	81 Å²	81	43 Å²	43	38%	0.379	21%	0.205	S	C	.	.	G	3₁₀ helix	trans	-57.4	-37.9	-171.5	65.9	-74.6	-11	0	0	113.7	Y419 H420	Q417-Y419 PolarHBondContact O-N 2.86Å; Q417-H420 PolarHBondContact O-N 3.03Å
418	H	78.9	Confident	86.9	Confident	74 Å²	74	44.1 Å²	44.1	34%	0.343	21%	0.21	S	C	.	.	G	3₁₀ helix	trans	-70.5	-7.8	-179.5	62.5	-73.3	0	0	0	114.3	R415 Q416	R415-H418 PolarHBondContact O-CE1 3.31Å; R415-H418 VanDerWaalsContact O-CE1 3.28Å; Q416-H418 VanDerWaalsContact C-N 3.29Å; Q416-H418 PolarHBondContact O-N 2.85Å
419	Y	76.4	Confident	87	Confident	28 Å²	28	42.9 Å²	42.9	11%	0.11	20%	0.204	C	C	.	.	G	3₁₀ helix	trans	-94.1	-9.7	174.9	-61.9	-58.9	0	0	0	113.6	I291 Y292 N293 Q416 Q417 Y455	I291-Y419 HydrophobicContact CD1-CD1 3.92Å; I291-Y419 HydrophobicContact CD1-CE1 3.38Å; I291-Y419 HydrophobicContact CG1-CE1 4.01Å; I291-Y419 HydrophobicContact CG2-CE2 4.29Å; Y292-Y419 PolarHBondContact O-OH 2.97Å; N293-Y419 HydrophobicContact CB-CE2 4.48Å; Q416-Y419 HydrophobicContact CB-CD2 4.23Å; Q416-Y419 HydrophobicContact CG-CD2 4.39Å; Q416-Y419 PolarHBondContact O-N 3.26Å; Q416-Y419 VanDerWaalsContact O-N 3.07Å; Q417-Y419 PolarHBondContact O-N 2.86Å; Y419-Y455 HydrophobicContact CD1-CD1 4.05Å; Y419-Y455 HydrophobicContact CD1-CG 4.39Å; Y419-Y455 HydrophobicContact CG-CD1 4.11Å; Y419-Y455 HydrophobicContact CG-CE1 4.29Å
420	H	83.8	Confident	87	Confident	10 Å²	10	40.9 Å²	40.9	5%	0.046	20%	0.197	C	C	.	.			trans	-140.4	91.3	-169.2	-54.7	-73.1	0	0	0	112.1	L411 Q416 Q417 I425 Y446 Y455	L411-H420 HydrophobicContact CD1-CB 4.09Å; Q416-H420 PolarHBondContact O-CD2 3.3Å; Q417-H420 PolarHBondContact O-N 3.03Å; H420-I425 HydrophobicContact CB-CD1 4.05Å; H420-I425 HydrophobicContact CB-CG1 4.13Å; H420-Y446 HydrophobicContact CB-CE1 4.42Å; H420-Y446 AromaticContact CE1-CD1 3.6Å; H420-Y446 AromaticContact CE1-CE1 3.83Å; H420-Y446 AromaticContact CG-CE1 3.93Å; H420-Y446 AromaticContact ND1-CD1 3.74Å; H420-Y446 AromaticContact ND1-CE1 3.54Å; H420-Y446 AromaticContact NE2-CD1 3.8Å; H420-Y455 AromaticContact CE1-CE1 3.64Å
421	S	86.4	Confident	87	Confident	56 Å²	56	45.4 Å²	45.4	39%	0.392	22%	0.217	S	C	.	.			trans	-68.4	156.2	168.3	66.7	0	0	0	0	111.7	E423 S424 I425	S421-E423 VanDerWaalsContact C-N 3.3Å; S421-E423 PolarHBondContact O-N 3.36Å; S421-S424 PolarHBondContact O-N 3.07Å; S421-S424 VanDerWaalsContact O-N 3.14Å; S421-S424 WeakPolarHBondContact OG-CB 3.29Å; S421-S424 PolarHBondContact OG-N 2.82Å; S421-I425 WeakPolarHBondContact O-CG1 3.35Å; S421-I425 PolarHBondContact O-N 2.98Å
422	M	87.4	Confident	87.2	Confident	55 Å²	55	45.1 Å²	45.1	27%	0.271	22%	0.216	S	C	.	.	H	α-helix	trans	-55.6	-43.5	176.1	176.4	167.3	163.8	0	0	112.1	W74 F400 S424 I425 L426	W74-M422 HydrophobicContact CB-SD 3.84Å; W74-M422 HydrophobicContact CD2-CB 4.17Å; W74-M422 HydrophobicContact CD2-SD 3.54Å; W74-M422 VanDerWaalsContact CD2-SD 3.54Å; W74-M422 HydrophobicContact CE3-SD 3.38Å; W74-M422 HydrophobicContact CG-CB 4.18Å; W74-M422 HydrophobicContact CG-SD 3.75Å; W74-M422 HydrophobicContact CZ3-SD 4.14Å; F400-M422 HydrophobicContact CD1-CE 4.03Å; F400-M422 HydrophobicContact CE1-CE 3.84Å; F400-M422 HydrophobicContact CE1-CG 3.87Å; F400-M422 HydrophobicContact CE1-SD 3.83Å; F400-M422 HydrophobicContact CZ-CG 4.18Å; M422-S424 PolarHBondContact O-N 3.13Å; M422-I425 PolarHBondContact O-N 3.4Å; M422-I425 VanDerWaalsContact O-N 3.15Å; M422-L426 HydrophobicContact CE-CD1 3.83Å; M422-L426 HydrophobicContact CG-CD1 4.07Å; M422-L426 HydrophobicContact CG-CG 4.41Å; M422-L426 WeakPolarHBondContact O-CG 3.4Å; M422-L426 PolarHBondContact O-N 2.93Å
423	E	87.6	Confident	87.3	Confident	97 Å²	97	41.3 Å²	41.3	45%	0.453	20%	0.202	S	C	.	.	H	α-helix	trans	-63.1	-41.2	177.2	-177.3	61.2	-166.1	0	0	111.9	R393 S421 I425 L426 Q427	R393-E423 IonicContact NH1-OE1 2.61Å; R393-E423 PolarHBondContact NH1-OE1 2.88Å; S421-E423 VanDerWaalsContact C-N 3.3Å; S421-E423 PolarHBondContact O-N 3.36Å; E423-I425 VanDerWaalsContact C-N 3.26Å; E423-I425 PolarHBondContact O-N 3.45Å; E423-L426 PolarHBondContact O-N 3.18Å; E423-Q427 VanDerWaalsContact O-CB 3.28Å; E423-Q427 WeakPolarHBondContact O-CB 3.41Å; E423-Q427 PolarHBondContact O-N 3.23Å
424	S	87.6	Confident	87.4	Confident	26 Å²	26	43.9 Å²	43.9	18%	0.182	22%	0.218	C	C	.	.	H	α-helix	trans	-65.2	-30.8	175.4	-178.5	0	0	0	0	112.5	S421 M422 H428 R445	S421-S424 PolarHBondContact O-N 3.07Å; S421-S424 VanDerWaalsContact O-N 3.14Å; S421-S424 WeakPolarHBondContact OG-CB 3.29Å; S421-S424 PolarHBondContact OG-N 2.82Å; M422-S424 PolarHBondContact O-N 3.13Å; S424-H428 WeakPolarHBondContact O-CB 3.42Å; S424-H428 PolarHBondContact O-N 3.42Å; S424-H428 VanDerWaalsContact O-N 3.16Å; S424-R445 PolarHBondContact OG-NH2 3.39Å
425	I	90.7	Very high	87.7	Confident	10 Å²	10	47.2 Å²	47.2	5%	0.051	24%	0.235	C	C	.	.	H	α-helix	trans	-73.7	-45.4	176.9	-65.1	160.7	0	0	0	110.2	F400 L407 H420 S421 M422 E423 H428 L429 F442 Y446	F400-I425 HydrophobicContact CD2-CG2 4.13Å; F400-I425 HydrophobicContact CE2-CB 4.42Å; F400-I425 HydrophobicContact CE2-CG2 3.62Å; L407-I425 HydrophobicContact CD2-CD1 3.98Å; L407-I425 HydrophobicContact CD2-CG1 4.39Å; L407-I425 HydrophobicContact CD2-CG2 3.78Å; H420-I425 HydrophobicContact CB-CD1 4.05Å; H420-I425 HydrophobicContact CB-CG1 4.13Å; S421-I425 WeakPolarHBondContact O-CG1 3.35Å; S421-I425 PolarHBondContact O-N 2.98Å; M422-I425 PolarHBondContact O-N 3.4Å; M422-I425 VanDerWaalsContact O-N 3.15Å; E423-I425 VanDerWaalsContact C-N 3.26Å; E423-I425 PolarHBondContact O-N 3.45Å; I425-H428 PolarHBondContact O-N 3.04Å; I425-L429 WeakPolarHBondContact O-CB 3.35Å; I425-L429 PolarHBondContact O-N 3.35Å; I425-F442 HydrophobicContact CG2-CZ 4.14Å; I425-Y446 HydrophobicContact CG1-CE1 3.97Å
426	L	91.6	Very high	88	Confident	14 Å²	14	48.4 Å²	48.4	7%	0.073	26%	0.256	C	S	.	.	H	α-helix	trans	-62.7	-42.6	176	-73	174.5	0	0	0	111.9	Q397 F400 M422 E423 H428 L429 A430	Q397-L426 HydrophobicContact CG-CD1 4.19Å; Q397-L426 HydrophobicContact CG-CD2 4.19Å; F400-L426 HydrophobicContact CB-CD2 3.64Å; F400-L426 HydrophobicContact CD1-CD2 4.1Å; F400-L426 HydrophobicContact CD2-CD2 4.28Å; F400-L426 HydrophobicContact CG-CD2 3.75Å; M422-L426 HydrophobicContact CE-CD1 3.83Å; M422-L426 HydrophobicContact CG-CD1 4.07Å; M422-L426 HydrophobicContact CG-CG 4.41Å; M422-L426 WeakPolarHBondContact O-CG 3.4Å; M422-L426 PolarHBondContact O-N 2.93Å; E423-L426 PolarHBondContact O-N 3.18Å; L426-H428 VanDerWaalsContact C-N 3.35Å; L426-H428 PolarHBondContact O-N 3.46Å; L426-L429 PolarHBondContact O-N 3.2Å; L426-A430 WeakPolarHBondContact O-CB 3.39Å; L426-A430 PolarHBondContact O-N 2.93Å
427	Q	91.4	Very high	88.4	Confident	111 Å²	111	50.6 Å²	50.6	52%	0.519	27%	0.267	S	S	.	.	H	α-helix	trans	-62.2	-41.3	175.3	-172.2	-178.8	13	0	0	111.8	E423 F431	E423-Q427 VanDerWaalsContact O-CB 3.28Å; E423-Q427 WeakPolarHBondContact O-CB 3.41Å; E423-Q427 PolarHBondContact O-N 3.23Å; Q427-F431 WeakPolarHBondContact O-CB 3.48Å; Q427-F431 PolarHBondContact O-N 2.98Å
428	H	91.1	Very high	89	Confident	26 Å²	26	50.7 Å²	50.7	12%	0.12	27%	0.274	C	S	.	.	H	α-helix	trans	-66.5	-39.9	175	-169.8	67.7	0	0	0	112	S424 I425 L426 F431 C432 F442 R445	S424-H428 WeakPolarHBondContact O-CB 3.42Å; S424-H428 PolarHBondContact O-N 3.42Å; S424-H428 VanDerWaalsContact O-N 3.16Å; I425-H428 PolarHBondContact O-N 3.04Å; L426-H428 VanDerWaalsContact C-N 3.35Å; L426-H428 PolarHBondContact O-N 3.46Å; H428-F431 PolarHBondContact O-N 3.47Å; H428-C432 PolarHBondContact O-N 3.04Å; H428-C432 PolarHBondContact O-SG 3.14Å; H428-F442 AromaticContact CD2-CD2 3.48Å; H428-F442 VanDerWaalsContact CD2-CD2 3.48Å; H428-F442 WeakPolarHBondContact CD2-CD2 3.25Å; H428-F442 AromaticContact CD2-CE2 3.75Å; H428-F442 PolarHBondContact NE2-O 3.46Å; H428-R445 WeakPolarHBondContact ND1-CD 3.38Å; H428-R445 PolarHBondContact ND1-NH1 3.42Å; H428-R445 VanDerWaalsContact ND1-NH1 3.16Å
429	L	92.6	Very high	89.6	Confident	0 Å²	0	48.4 Å²	48.4	0%	0	27%	0.265	C	S	.	.	H	α-helix	trans	-65.6	-47.2	178	-174.1	56.4	0	0	0	111.6	F371 A396 I399 F400 M403 I425 L426 F431 C432 I433 F442	F371-L429 HydrophobicContact CE2-CD1 3.68Å; F371-L429 HydrophobicContact CZ-CD1 3.8Å; A396-L429 HydrophobicContact CB-CB 4Å; A396-L429 HydrophobicContact CB-CD2 3.94Å; A396-L429 HydrophobicContact CB-CG 3.78Å; I399-L429 HydrophobicContact CD1-CD1 4.05Å; I399-L429 HydrophobicContact CD1-CD2 3.95Å; I399-L429 HydrophobicContact CD1-CG 4.32Å; I399-L429 HydrophobicContact CG1-CD2 3.94Å; F400-L429 HydrophobicContact CB-CD2 4.33Å; M403-L429 HydrophobicContact CE-CD1 4.35Å; M403-L429 HydrophobicContact CE-CD2 4.35Å; M403-L429 HydrophobicContact SD-CD2 4.28Å; I425-L429 WeakPolarHBondContact O-CB 3.35Å; I425-L429 PolarHBondContact O-N 3.35Å; L426-L429 PolarHBondContact O-N 3.2Å; L429-F431 VanDerWaalsContact C-N 3.34Å; L429-F431 PolarHBondContact O-N 3.42Å; L429-C432 WeakPolarHBondContact O-CB 3.44Å; L429-C432 PolarHBondContact O-N 3.44Å; L429-C432 VanDerWaalsContact O-N 3.14Å; L429-I433 HydrophobicContact CG-CD1 4.25Å; L429-I433 WeakPolarHBondContact O-CG1 3.42Å; L429-I433 PolarHBondContact O-N 3.23Å; L429-F442 HydrophobicContact CB-CD2 4.24Å; L429-F442 HydrophobicContact CB-CE2 3.69Å; L429-F442 HydrophobicContact CB-CZ 4.47Å; L429-F442 HydrophobicContact CD1-CD2 3.78Å; L429-F442 HydrophobicContact CD1-CE2 3.74Å; L429-F442 HydrophobicContact CD1-CG 4.31Å; L429-F442 HydrophobicContact CD1-CZ 4.21Å; L429-F442 HydrophobicContact CG-CE2 4.24Å
430	A	91.9	Very high	90.3	Very high	8 Å²	8	54 Å²	54	7%	0.066	29%	0.29	C	S	.	.	H	α-helix	trans	-57.5	-46.4	173.8	0	0	0	0	0	111.1	P392 R393 A396 L426 C432 I433 T434	P392-A430 WeakPolarHBondContact O-CB 3.37Å; R393-A430 HydrophobicContact CG-CB 4.03Å; A396-A430 HydrophobicContact CB-CB 4.07Å; L426-A430 WeakPolarHBondContact O-CB 3.39Å; L426-A430 PolarHBondContact O-N 2.93Å; A430-C432 VanDerWaalsContact C-N 3.33Å; A430-C432 PolarHBondContact O-N 3.13Å; A430-I433 PolarHBondContact O-N 3.33Å; A430-I433 VanDerWaalsContact O-N 3.11Å; A430-T434 PolarHBondContact O-N 2.92Å; A430-T434 PolarHBondContact O-OG1 3.21Å
431	F	92.1	Very high	90.7	Very high	110 Å²	110	55.3 Å²	55.3	48%	0.482	30%	0.302	S	S	.	.	H	α-helix	trans	-59.3	-40.4	174.8	177	-97.7	0	0	0	112.9	Q427 H428 L429 N435 M437	Q427-F431 WeakPolarHBondContact O-CB 3.48Å; Q427-F431 PolarHBondContact O-N 2.98Å; H428-F431 PolarHBondContact O-N 3.47Å; L429-F431 VanDerWaalsContact C-N 3.34Å; L429-F431 PolarHBondContact O-N 3.42Å; F431-N435 WeakPolarHBondContact CD2-ND2 3.46Å; F431-N435 VanDerWaalsContact CE2-ND2 3.33Å; F431-N435 WeakPolarHBondContact CE2-ND2 3.27Å; F431-N435 PolarHBondContact O-N 2.84Å; F431-N435 PolarHBondContact O-ND2 3.3Å; F431-M437 HydrophobicContact CD1-CE 4.2Å; F431-M437 HydrophobicContact CD1-SD 4.5Å; F431-M437 HydrophobicContact CE1-CE 3.48Å; F431-M437 VanDerWaalsContact CE1-CE 3.48Å; F431-M437 HydrophobicContact CE1-SD 4.24Å; F431-M437 HydrophobicContact CZ-CE 4.04Å
432	C	92.7	Very high	90.9	Very high	0 Å²	0	52.6 Å²	52.6	0%	0	28%	0.284	C	S	.	.	H	α-helix	trans	-63.8	-39.3	173.7	-72.2	0	0	0	0	112.5	F371 H428 L429 A430 S436 M437 F442	F371-C432 HydrophobicContact CZ-CB 4.27Å; H428-C432 PolarHBondContact O-N 3.04Å; H428-C432 PolarHBondContact O-SG 3.14Å; L429-C432 WeakPolarHBondContact O-CB 3.44Å; L429-C432 PolarHBondContact O-N 3.44Å; L429-C432 VanDerWaalsContact O-N 3.14Å; A430-C432 VanDerWaalsContact C-N 3.33Å; A430-C432 PolarHBondContact O-N 3.13Å; C432-S436 PolarHBondContact O-N 2.95Å; C432-M437 HydrophobicContact CB-CB 4Å; C432-M437 HydrophobicContact CB-CG 4.49Å; C432-M437 HydrophobicContact CB-SD 4.45Å; C432-M437 WeakPolarHBondContact O-CB 3.32Å; C432-M437 PolarHBondContact O-N 3.42Å; C432-F442 HydrophobicContact CB-CB 4.39Å
433	I	90.3	Very high	91.2	Very high	13 Å²	13	50.1 Å²	50.1	7%	0.067	27%	0.272	C	S	.	.	H	α-helix	trans	-66.6	-49.1	177.1	-65.4	165.3	0	0	0	110.7	I374 P392 A395 A396 L429 A430 N435 S436	I374-I433 HydrophobicContact CD1-CD1 3.81Å; I374-I433 HydrophobicContact CD1-CG1 3.7Å; P392-I433 HydrophobicContact CB-CB 4.5Å; P392-I433 HydrophobicContact CB-CG2 4.24Å; A395-I433 HydrophobicContact CB-CD1 4Å; A395-I433 HydrophobicContact CB-CG2 4.42Å; A396-I433 HydrophobicContact CB-CD1 3.97Å; L429-I433 HydrophobicContact CG-CD1 4.25Å; L429-I433 WeakPolarHBondContact O-CG1 3.42Å; L429-I433 PolarHBondContact O-N 3.23Å; A430-I433 PolarHBondContact O-N 3.33Å; A430-I433 VanDerWaalsContact O-N 3.11Å; I433-N435 PolarHBondContact O-N 3.45Å; I433-S436 PolarHBondContact O-N 2.93Å; I433-S436 VanDerWaalsContact O-N 3.07Å
434	T	90.9	Very high	91.3	Very high	88 Å²	88	49.7 Å²	49.7	54%	0.54	27%	0.27	S	S	.	.	H	α-helix	trans	-56.7	-33.7	178.9	-53	0	0	0	0	112.8	P392 A430	P392-T434 VanDerWaalsContact CB-OG1 3.28Å; P392-T434 WeakPolarHBondContact CB-OG1 3.32Å; P392-T434 WeakPolarHBondContact CG-OG1 3.26Å; A430-T434 PolarHBondContact O-N 2.92Å; A430-T434 PolarHBondContact O-OG1 3.21Å
435	N	91.3	Very high	91.2	Very high	84 Å²	84	51 Å²	51	45%	0.449	27%	0.271	S	S	.	.	T	Hydrogen-bonded Turn	trans	-99.9	13.8	-178.5	-66.8	-84	0	0	0	113.4	F431 I433 M437	F431-N435 WeakPolarHBondContact CD2-ND2 3.46Å; F431-N435 VanDerWaalsContact CE2-ND2 3.33Å; F431-N435 WeakPolarHBondContact CE2-ND2 3.27Å; F431-N435 PolarHBondContact O-N 2.84Å; F431-N435 PolarHBondContact O-ND2 3.3Å; I433-N435 PolarHBondContact O-N 3.45Å; N435-M437 HydrophobicContact CB-CE 3.7Å; N435-M437 HydrophobicContact CB-CG 3.87Å; N435-M437 HydrophobicContact CB-SD 4.5Å; N435-M437 PolarHBondContact O-N 3.39Å; N435-M437 VanDerWaalsContact O-N 3.12Å
436	S	88.6	Confident	91.1	Very high	108 Å²	108	50.6 Å²	50.6	76%	0.755	27%	0.268	S	S	*	.	T	Hydrogen-bonded Turn	trans	50.4	37	-179.3	-60.3	0	0	0	0	114	C432 I433	C432-S436 PolarHBondContact O-N 2.95Å; I433-S436 PolarHBondContact O-N 2.93Å; I433-S436 VanDerWaalsContact O-N 3.07Å
437	M	91.6	Very high	90.9	Very high	63 Å²	63	51.7 Å²	51.7	31%	0.31	27%	0.274	S	S	.	.			trans	-74.2	152.5	-175.9	-62.8	-166.2	176.2	0	0	112.2	F371 F431 C432 N435 A441	F371-M437 WeakPolarHBondContact CE1-O 3.27Å; F431-M437 HydrophobicContact CD1-CE 4.2Å; F431-M437 HydrophobicContact CD1-SD 4.5Å; F431-M437 HydrophobicContact CE1-CE 3.48Å; F431-M437 VanDerWaalsContact CE1-CE 3.48Å; F431-M437 HydrophobicContact CE1-SD 4.24Å; F431-M437 HydrophobicContact CZ-CE 4.04Å; C432-M437 HydrophobicContact CB-CB 4Å; C432-M437 HydrophobicContact CB-CG 4.49Å; C432-M437 HydrophobicContact CB-SD 4.45Å; C432-M437 WeakPolarHBondContact O-CB 3.32Å; C432-M437 PolarHBondContact O-N 3.42Å; N435-M437 HydrophobicContact CB-CE 3.7Å; N435-M437 HydrophobicContact CB-CG 3.87Å; N435-M437 HydrophobicContact CB-SD 4.5Å; N435-M437 PolarHBondContact O-N 3.39Å; N435-M437 VanDerWaalsContact O-N 3.12Å; M437-A441 HydrophobicContact CB-CB 4.12Å; M437-A441 HydrophobicContact SD-CB 4.47Å
438	T	93.1	Very high	90.3	Very high	84 Å²	84	48.8 Å²	48.8	52%	0.515	27%	0.266	S	S	.	.			trans	-74.9	158.2	178	68.1	0	0	0	0	112.3	K440 A441 F442	T438-K440 PolarHBondContact O-N 2.82Å; T438-K440 VanDerWaalsContact O-N 3.08Å; T438-A441 WeakPolarHBondContact O-CB 3.22Å; T438-A441 PolarHBondContact O-N 3.22Å; T438-A441 PolarHBondContact OG1-N 2.87Å; T438-F442 PolarHBondContact O-N 3.11Å
439	P	92.4	Very high	89.2	Confident	25 Å²	25	49 Å²	49	16%	0.162	27%	0.272	C	S	.	.	H	α-helix	trans	-50	-36.6	172.4	-28.2	34.2	0	0	0	113.3	V367 E368 F371 F442 L443	V367-P439 HydrophobicContact CG1-CB 4.07Å; E368-P439 HydrophobicContact CG-CB 3.85Å; E368-P439 HydrophobicContact CG-CG 4.18Å; F371-P439 HydrophobicContact CB-CG 3.67Å; F371-P439 HydrophobicContact CD1-CG 4.13Å; F371-P439 HydrophobicContact CD2-CB 4.46Å; F371-P439 HydrophobicContact CD2-CG 4.4Å; F371-P439 HydrophobicContact CG-CB 4.35Å; F371-P439 HydrophobicContact CG-CG 3.82Å; P439-F442 PolarHBondContact O-N 2.97Å; P439-L443 WeakPolarHBondContact O-CB 3.44Å; P439-L443 VanDerWaalsContact O-CG 3.25Å; P439-L443 WeakPolarHBondContact O-CG 3.48Å; P439-L443 PolarHBondContact O-N 3.15Å
440	K	91.6	Very high	88	Confident	146 Å²	146	49.3 Å²	49.3	64%	0.635	28%	0.275	S	S	*	.	H	α-helix	trans	-69.5	-32.7	-179.6	-66.4	176.8	-179	171	0	112.6	T438 L443 E444	T438-K440 PolarHBondContact O-N 2.82Å; T438-K440 VanDerWaalsContact O-N 3.08Å; K440-L443 PolarHBondContact O-N 2.9Å; K440-E444 PolarHBondContact O-N 3.3Å
441	A	90.7	Very high	87.1	Confident	37 Å²	37	50.9 Å²	50.9	31%	0.306	29%	0.285	S	S	.	.	H	α-helix	trans	-73.4	-37.6	175.3	0	0	0	0	0	111.9	M437 T438 L443 E444	M437-A441 HydrophobicContact CB-CB 4.12Å; M437-A441 HydrophobicContact SD-CB 4.47Å; T438-A441 WeakPolarHBondContact O-CB 3.22Å; T438-A441 PolarHBondContact O-N 3.22Å; T438-A441 PolarHBondContact OG1-N 2.87Å; A441-L443 VanDerWaalsContact C-N 3.33Å; A441-E444 PolarHBondContact O-N 3.01Å
442	F	92.2	Very high	85.9	Confident	0 Å²	0	46.3 Å²	46.3	0%	0	27%	0.266	C	S	.	.	H	α-helix	trans	-60.5	-44.8	169.1	171.8	-98.4	0	0	0	111.4	V367 F371 M403 I425 H428 L429 C432 T438 P439 E444 Y446	V367-F442 HydrophobicContact CG1-CD1 3.74Å; V367-F442 HydrophobicContact CG1-CE1 4.3Å; V367-F442 HydrophobicContact CG2-CD1 4.34Å; V367-F442 HydrophobicContact CG2-CE1 4.17Å; F371-F442 HydrophobicContact CE2-CB 4.13Å; F371-F442 HydrophobicContact CE2-CD1 4.41Å; F371-F442 HydrophobicContact CE2-CG 4.23Å; F371-F442 HydrophobicContact CZ-CB 3.79Å; F371-F442 HydrophobicContact CZ-CG 4.21Å; M403-F442 HydrophobicContact SD-CE1 3.82Å; M403-F442 HydrophobicContact SD-CZ 4Å; I425-F442 HydrophobicContact CG2-CZ 4.14Å; H428-F442 AromaticContact CD2-CD2 3.48Å; H428-F442 VanDerWaalsContact CD2-CD2 3.48Å; H428-F442 WeakPolarHBondContact CD2-CD2 3.25Å; H428-F442 AromaticContact CD2-CE2 3.75Å; H428-F442 PolarHBondContact NE2-O 3.46Å; L429-F442 HydrophobicContact CB-CD2 4.24Å; L429-F442 HydrophobicContact CB-CE2 3.69Å; L429-F442 HydrophobicContact CB-CZ 4.47Å; L429-F442 HydrophobicContact CD1-CD2 3.78Å; L429-F442 HydrophobicContact CD1-CE2 3.74Å; L429-F442 HydrophobicContact CD1-CG 4.31Å; L429-F442 HydrophobicContact CD1-CZ 4.21Å; L429-F442 HydrophobicContact CG-CE2 4.24Å; C432-F442 HydrophobicContact CB-CB 4.39Å; T438-F442 PolarHBondContact O-N 3.11Å; P439-F442 PolarHBondContact O-N 2.97Å; F442-E444 VanDerWaalsContact C-N 3.33Å; F442-E444 PolarHBondContact O-N 3.17Å; F442-Y446 HydrophobicContact CD1-CE2 4.23Å; F442-Y446 HydrophobicContact CD2-CE2 4.31Å; F442-Y446 HydrophobicContact CE1-CD2 4.33Å; F442-Y446 AromaticContact CE1-CE2 3.77Å; F442-Y446 HydrophobicContact CE1-CE2 3.77Å; F442-Y446 AromaticContact CE2-CE2 3.83Å; F442-Y446 HydrophobicContact CE2-CE2 3.83Å; F442-Y446 HydrophobicContact CG-CE2 4.49Å; F442-Y446 AromaticContact CZ-CE2 3.55Å; F442-Y446 HydrophobicContact CZ-CE2 3.55Å; F442-Y446 WeakPolarHBondContact O-CD2 3.28Å; F442-Y446 WeakPolarHBondContact O-CE2 3.33Å
443	L	92.5	Very high	84.6	Confident	3 Å²	3	51.2 Å²	51.2	2%	0.016	29%	0.292	C	S	.	.	H	α-helix	trans	-69.6	-22.6	-178.5	-74.8	170	0	0	0	114.9	L363 V364 V367 P439 K440 A441 R445 Y446 L447	L363-L443 HydrophobicContact CD1-CD2 4.05Å; L363-L443 HydrophobicContact CD2-CD2 3.97Å; L363-L443 HydrophobicContact CG-CD2 3.66Å; V364-L443 HydrophobicContact CB-CD1 4.38Å; V364-L443 HydrophobicContact CG2-CD1 4.05Å; V367-L443 HydrophobicContact CB-CD1 4.18Å; V367-L443 HydrophobicContact CB-CD2 4.3Å; V367-L443 HydrophobicContact CB-CG 4.29Å; V367-L443 HydrophobicContact CG1-CD1 4.32Å; V367-L443 HydrophobicContact CG1-CG 4.15Å; V367-L443 HydrophobicContact CG2-CD2 3.87Å; V367-L443 HydrophobicContact CG2-CG 4.37Å; P439-L443 WeakPolarHBondContact O-CB 3.44Å; P439-L443 VanDerWaalsContact O-CG 3.25Å; P439-L443 WeakPolarHBondContact O-CG 3.48Å; P439-L443 PolarHBondContact O-N 3.15Å; K440-L443 PolarHBondContact O-N 2.9Å; A441-L443 VanDerWaalsContact C-N 3.33Å; L443-R445 VanDerWaalsContact C-N 3.27Å; L443-R445 PolarHBondContact O-N 2.92Å; L443-Y446 PolarHBondContact O-N 3.2Å; L443-Y446 VanDerWaalsContact O-N 3.1Å; L443-L447 HydrophobicContact CB-CD1 3.85Å; L443-L447 HydrophobicContact CB-CG 4.14Å; L443-L447 HydrophobicContact CD1-CD1 4.36Å; L443-L447 HydrophobicContact CD2-CD1 4.41Å; L443-L447 HydrophobicContact CD2-CG 4.44Å; L443-L447 HydrophobicContact CG-CD1 4.45Å; L443-L447 WeakPolarHBondContact O-CB 3.21Å; L443-L447 WeakPolarHBondContact O-CG 3.44Å; L443-L447 PolarHBondContact O-N 3.49Å
444	E	89.9	Confident	83.3	Confident	88 Å²	88	54 Å²	54	41%	0.411	30%	0.304	S	S	.	.	H	α-helix	trans	-53.2	-44.9	-178.7	-175.5	-80.7	158.9	0	0	111.6	K440 A441 F442 Y446 S448	K440-E444 PolarHBondContact O-N 3.3Å; A441-E444 PolarHBondContact O-N 3.01Å; F442-E444 VanDerWaalsContact C-N 3.33Å; F442-E444 PolarHBondContact O-N 3.17Å; E444-Y446 PolarHBondContact O-N 3.16Å; E444-Y446 VanDerWaalsContact O-N 3.15Å; E444-S448 WeakPolarHBondContact O-CB 3.38Å; E444-S448 PolarHBondContact O-N 3.39Å; E444-S448 PolarHBondContact O-OG 3.1Å
445	R	86.3	Confident	82.1	Confident	54 Å²	54	51.4 Å²	51.4	20%	0.204	29%	0.285	C	S	.	.	H	α-helix	trans	-62.1	-21.5	-179.3	-172.1	170.5	-177	-177.3	-3.4	114.9	S424 H428 L443 Y455	S424-R445 PolarHBondContact OG-NH2 3.39Å; H428-R445 WeakPolarHBondContact ND1-CD 3.38Å; H428-R445 PolarHBondContact ND1-NH1 3.42Å; H428-R445 VanDerWaalsContact ND1-NH1 3.16Å; L443-R445 VanDerWaalsContact C-N 3.27Å; L443-R445 PolarHBondContact O-N 2.92Å; R445-Y455 PolarHBondContact O-OH 2.95Å
446	Y	87.6	Confident	80.4	Confident	0 Å²	0	50.5 Å²	50.5	0%	0	28%	0.28	C	S	.	.	H	α-helix	trans	-109.7	-38.3	-177.2	-49.4	-74.6	0	0	0	112.3	L407 Y410 L411 H420 I425 F442 L443 E444	L407-Y446 HydrophobicContact CD1-CD1 4.16Å; L407-Y446 HydrophobicContact CD1-CD2 4.24Å; L407-Y446 HydrophobicContact CD1-CG 3.93Å; Y410-Y446 WeakPolarHBondContact CE1-O 3.49Å; L411-Y446 HydrophobicContact CD2-CD1 4.33Å; H420-Y446 HydrophobicContact CB-CE1 4.42Å; H420-Y446 AromaticContact CE1-CD1 3.6Å; H420-Y446 AromaticContact CE1-CE1 3.83Å; H420-Y446 AromaticContact CG-CE1 3.93Å; H420-Y446 AromaticContact ND1-CD1 3.74Å; H420-Y446 AromaticContact ND1-CE1 3.54Å; H420-Y446 AromaticContact NE2-CD1 3.8Å; I425-Y446 HydrophobicContact CG1-CE1 3.97Å; F442-Y446 HydrophobicContact CD1-CE2 4.23Å; F442-Y446 HydrophobicContact CD2-CE2 4.31Å; F442-Y446 HydrophobicContact CE1-CD2 4.33Å; F442-Y446 AromaticContact CE1-CE2 3.77Å; F442-Y446 HydrophobicContact CE1-CE2 3.77Å; F442-Y446 AromaticContact CE2-CE2 3.83Å; F442-Y446 HydrophobicContact CE2-CE2 3.83Å; F442-Y446 HydrophobicContact CG-CE2 4.49Å; F442-Y446 AromaticContact CZ-CE2 3.55Å; F442-Y446 HydrophobicContact CZ-CE2 3.55Å; F442-Y446 WeakPolarHBondContact O-CD2 3.28Å; F442-Y446 WeakPolarHBondContact O-CE2 3.33Å; L443-Y446 PolarHBondContact O-N 3.2Å; L443-Y446 VanDerWaalsContact O-N 3.1Å; E444-Y446 PolarHBondContact O-N 3.16Å; E444-Y446 VanDerWaalsContact O-N 3.15Å
447	L	87.2	Confident	78.7	Confident	37 Å²	37	54.6 Å²	54.6	19%	0.194	28%	0.284	C	S	.	.	H	α-helix	trans	-80	-25.2	-178	-63.3	-172.9	0	0	0	112.9	R360 L363 V364 Y410 L443	R360-L447 HydrophobicContact CG-CD1 4.31Å; R360-L447 HydrophobicContact CG-CD2 3.88Å; L363-L447 HydrophobicContact CD2-CD2 4.02Å; V364-L447 HydrophobicContact CG2-CD1 4.08Å; Y410-L447 HydrophobicContact CD1-CD2 4.27Å; Y410-L447 HydrophobicContact CE1-CD2 3.66Å; Y410-L447 HydrophobicContact CE2-CD2 4.1Å; L443-L447 HydrophobicContact CB-CD1 3.85Å; L443-L447 HydrophobicContact CB-CG 4.14Å; L443-L447 HydrophobicContact CD1-CD1 4.36Å; L443-L447 HydrophobicContact CD2-CD1 4.41Å; L443-L447 HydrophobicContact CD2-CG 4.44Å; L443-L447 HydrophobicContact CG-CD1 4.45Å; L443-L447 WeakPolarHBondContact O-CB 3.21Å; L443-L447 WeakPolarHBondContact O-CG 3.44Å; L443-L447 PolarHBondContact O-N 3.49Å
448	S	78.7	Confident	76.8	Confident	50 Å²	50	58.4 Å²	58.4	35%	0.35	31%	0.306	S	S	.	.	S	Bend	trans	-108.5	126.7	167.4	-0.1	0	0	0	0	107.4	E444 G450	E444-S448 WeakPolarHBondContact O-CB 3.38Å; E444-S448 PolarHBondContact O-N 3.39Å; E444-S448 PolarHBondContact O-OG 3.1Å; S448-G450 PolarHBondContact O-N 3.48Å
449	A	68.1	Low	75.1	Confident	31 Å²	31	59.2 Å²	59.2	26%	0.256	30%	0.3	S	S	.	.			trans	-69.3	91	164	0	0	0	0	0	107.4	T290 I291	T290-A449 WeakPolarHBondContact CB-O 3.4Å; T290-A449 HydrophobicContact CG2-CB 4.35Å; T290-A449 WeakPolarHBondContact CG2-O 3.46Å; I291-A449 HydrophobicContact CG2-CB 4.33Å
450	G	68.7	Low	73	Confident	6 Å²	6	65.6 Å²	65.6	6%	0.062	32%	0.32	C	S	.	.			trans	-61.2	176.9	-178.4	0	0	0	0	0	113.5	S448	S448-G450 PolarHBondContact O-N 3.48Å
451	P	71.9	Confident	70.9	Confident	41 Å²	41	62.2 Å²	62.2	27%	0.266	31%	0.309	S	S	.	.	B	Isolated β-bridge	trans	-56.9	146.7	-177	20.8	-32	0	0	0	112.9	Y286 K287 L453 Q454	Y286-P451 WeakPolarHBondContact O-CB 3.43Å; K287-P451 VanDerWaalsContact O-CB 3.31Å; K287-P451 WeakPolarHBondContact O-CB 3.41Å; P451-L453 PolarHBondContact O-N 3.05Å; P451-Q454 HydrophobicContact CG-CG 4.15Å; P451-Q454 WeakPolarHBondContact O-CB 3.38Å; P451-Q454 PolarHBondContact O-N 2.93Å
452	T	67.2	Low	69.2	Low	15 Å²	15	61.8 Å²	61.8	9%	0.092	30%	0.304	C	S	.	.	G	3₁₀ helix	trans	-48.7	-35.4	-176.2	-57.2	0	0	0	0	113	Y286 Q454 Y455	Y286-T452 HydrophobicContact CD1-CG2 3.85Å; Y286-T452 HydrophobicContact CE1-CG2 4.06Å; Y286-T452 PolarHBondContact O-N 3.48Å; T452-Q454 PolarHBondContact O-N 3.22Å; T452-Q454 VanDerWaalsContact O-N 3.1Å; T452-Y455 PolarHBondContact O-N 3.32Å
453	L	65.3	Low	67.8	Low	102 Å²	102	65.9 Å²	65.9	53%	0.534	33%	0.329	S	S	.	.	G	3₁₀ helix	trans	-54.7	-22.7	175.6	-73.5	161.7	0	0	0	115.7	Y286 P451 Y455	Y286-L453 WeakPolarHBondContact O-CD1 3.31Å; Y286-L453 WeakPolarHBondContact O-CG 3.48Å; Y286-L453 PolarHBondContact O-N 3.44Å; P451-L453 PolarHBondContact O-N 3.05Å; L453-Y455 PolarHBondContact O-N 3.31Å
454	Q	63.3	Low	67	Low	71 Å²	71	70.9 Å²	70.9	33%	0.332	35%	0.352	S	S	.	.	G	3₁₀ helix	trans	-73	-10	-176.8	-70.1	-177.4	-10.1	0	0	114.4	P451 T452	P451-Q454 HydrophobicContact CG-CG 4.15Å; P451-Q454 WeakPolarHBondContact O-CB 3.38Å; P451-Q454 PolarHBondContact O-N 2.93Å; T452-Q454 PolarHBondContact O-N 3.22Å; T452-Q454 VanDerWaalsContact O-N 3.1Å
455	Y	65	Low	66.8	Low	34 Å²	34	68.7 Å²	68.7	13%	0.133	34%	0.34	C	S	.	.	G	3₁₀ helix	trans	-125.3	14	-167.8	-58.3	-82.1	0	0	0	113.2	I291 Y419 H420 R445 T452 L453 K457	I291-Y455 HydrophobicContact CB-CD2 4.17Å; I291-Y455 HydrophobicContact CB-CE2 4.4Å; I291-Y455 HydrophobicContact CD1-CD1 4.49Å; I291-Y455 HydrophobicContact CD1-CD2 3.55Å; I291-Y455 HydrophobicContact CD1-CE2 4.44Å; I291-Y455 HydrophobicContact CD1-CG 3.59Å; I291-Y455 HydrophobicContact CG1-CD2 4.48Å; I291-Y455 HydrophobicContact CG2-CD2 4.23Å; I291-Y455 HydrophobicContact CG2-CE2 4.06Å; Y419-Y455 HydrophobicContact CD1-CD1 4.05Å; Y419-Y455 HydrophobicContact CD1-CG 4.39Å; Y419-Y455 HydrophobicContact CG-CD1 4.11Å; Y419-Y455 HydrophobicContact CG-CE1 4.29Å; H420-Y455 AromaticContact CE1-CE1 3.64Å; R445-Y455 PolarHBondContact O-OH 2.95Å; T452-Y455 PolarHBondContact O-N 3.32Å; L453-Y455 PolarHBondContact O-N 3.31Å; Y455-K457 PolarHBondContact O-N 3.08Å
456	D	56.2	Low	67	Low	65 Å²	65	74.7 Å²	74.7	35%	0.348	36%	0.363	S	S	.	.			trans	-101.9	46	-151.7	-158.7	22.9	0	0	0	114.8
457	K	53.6	Low	67.2	Low	194 Å²	194	76.9 Å²	76.9	84%	0.843	38%	0.375	S	S	*	.	S	Bend	trans	-85.5	-41.8	177.4	-89	-170.2	170.8	-174.5	0	114.3	Y455	Y455-K457 PolarHBondContact O-N 3.08Å
458	D	52.1	Low	67.4	Low	143 Å²	143	78.9 Å²	78.9	77%	0.765	39%	0.385	S	S	*	.	S	Bend	trans	-118.7	-1	-167.3	-51.9	-58.8	0	0	0	114.1	W460	D458-W460 VanDerWaalsContact C-N 3.33Å; D458-W460 PolarHBondContact O-N 3.4Å
459	R	56.3	Low	68	Low	102 Å²	102	77.8 Å²	77.8	39%	0.385	38%	0.377	S	S	.	.			trans	-91.9	40.2	-175.8	-71.5	-173.6	172.2	-115.1	-5.7	114.3	L461 S462	R459-L461 VanDerWaalsContact C-N 3.25Å; R459-L461 PolarHBondContact O-N 2.97Å; R459-L461 VanDerWaalsContact O-N 3.15Å; R459-S462 VanDerWaalsContact O-CB 3.31Å; R459-S462 WeakPolarHBondContact O-CB 3.4Å; R459-S462 PolarHBondContact O-N 2.86Å; R459-S462 PolarHBondContact O-OG 2.64Å
460	W	49.6	Very low	69	Low	158 Å²	158	84.2 Å²	84.2	60%	0.598	41%	0.407	S	S	*	.	G	3₁₀ helix	trans	-53.2	-37.9	-178	69	-80.8	0	0	0	113.8	I97 D458 S462 T463	I97-W460 HydrophobicContact CG1-CH2 4.33Å; D458-W460 VanDerWaalsContact C-N 3.33Å; D458-W460 PolarHBondContact O-N 3.4Å; W460-S462 PolarHBondContact O-N 3.08Å; W460-T463 WeakPolarHBondContact O-CB 3.5Å; W460-T463 WeakPolarHBondContact O-CG2 3.33Å; W460-T463 PolarHBondContact O-N 3.45Å; W460-T463 VanDerWaalsContact O-N 3.09Å; W460-T463 PolarHBondContact O-OG1 3.13Å
461	L	47.4	Very low	69.9	Low	75 Å²	75	86.8 Å²	86.8	39%	0.393	42%	0.417	S	S	.	.	G	3₁₀ helix	trans	-61.3	-21.2	175.1	-75.1	161.9	0	0	0	114.3	R459 T463 L488	R459-L461 VanDerWaalsContact C-N 3.25Å; R459-L461 PolarHBondContact O-N 2.97Å; R459-L461 VanDerWaalsContact O-N 3.15Å; L461-T463 PolarHBondContact O-N 3.33Å; L461-L488 HydrophobicContact CB-CD1 3.96Å; L461-L488 HydrophobicContact CD2-CD1 4.48Å
462	S	55.1	Low	70.6	Confident	28 Å²	28	87.2 Å²	87.2	20%	0.196	42%	0.424	C	S	.	.	G	3₁₀ helix	trans	-75.8	-7	176	76.4	0	0	0	0	113.9	Y286 R459 W460 W465	Y286-S462 PolarHBondContact OH-O 3.12Å; R459-S462 VanDerWaalsContact O-CB 3.31Å; R459-S462 WeakPolarHBondContact O-CB 3.4Å; R459-S462 PolarHBondContact O-N 2.86Å; R459-S462 PolarHBondContact O-OG 2.64Å; W460-S462 PolarHBondContact O-N 3.08Å; S462-W465 PolarHBondContact O-NE1 3.07Å
463	T	63	Low	71.4	Confident	87 Å²	87	87.8 Å²	87.8	53%	0.534	43%	0.427	S	S	.	.	G	3₁₀ helix	trans	-84.4	-14.2	178.4	67.1	0	0	0	0	113.8	W460 L461 W465	W460-T463 WeakPolarHBondContact O-CB 3.5Å; W460-T463 WeakPolarHBondContact O-CG2 3.33Å; W460-T463 PolarHBondContact O-N 3.45Å; W460-T463 VanDerWaalsContact O-N 3.09Å; W460-T463 PolarHBondContact O-OG1 3.13Å; L461-T463 PolarHBondContact O-N 3.33Å; T463-W465 VanDerWaalsContact O-CD1 3.29Å; T463-W465 PolarHBondContact O-N 3.04Å
464	Q	75.3	Confident	72.2	Confident	108 Å²	108	85.3 Å²	85.3	51%	0.505	42%	0.417	S	S	.	.			trans	-86.2	102.1	-179.1	-162.8	-175.9	16.8	0	0	111
465	W	86	Confident	73.2	Confident	42 Å²	42	84.7 Å²	84.7	16%	0.159	42%	0.416	C	S	.	.			trans	-106.1	130.9	179.9	-69.2	89	0	0	0	112.5	L282 Y285 Y286 S462 T463 L485 C487 F490 L492	L282-W465 HydrophobicContact CD1-CB 3.74Å; L282-W465 HydrophobicContact CD1-CD2 4.29Å; L282-W465 HydrophobicContact CD1-CG 3.68Å; L282-W465 HydrophobicContact CD2-CB 4.43Å; L282-W465 HydrophobicContact CD2-CD2 3.38Å; L282-W465 VanDerWaalsContact CD2-CE2 3.48Å; L282-W465 HydrophobicContact CD2-CE3 3.75Å; L282-W465 HydrophobicContact CD2-CG 3.7Å; L282-W465 HydrophobicContact CD2-CH2 4.16Å; L282-W465 HydrophobicContact CD2-CZ2 3.88Å; L282-W465 HydrophobicContact CD2-CZ3 4.11Å; L282-W465 HydrophobicContact CG-CD2 4.49Å; L282-W465 HydrophobicContact CG-CG 4.36Å; Y285-W465 HydrophobicContact CD1-CH2 4.44Å; Y285-W465 HydrophobicContact CD1-CZ2 4.05Å; Y285-W465 HydrophobicContact CE1-CH2 4.37Å; Y285-W465 HydrophobicContact CE1-CZ2 4.05Å; Y286-W465 AromaticContact CE2-NE1 3.87Å; Y286-W465 AromaticContact CZ-NE1 3.75Å; Y286-W465 PolarHBondContact OH-NE1 3.03Å; S462-W465 PolarHBondContact O-NE1 3.07Å; T463-W465 VanDerWaalsContact O-CD1 3.29Å; T463-W465 PolarHBondContact O-N 3.04Å; W465-L485 HydrophobicContact CE3-CB 3.78Å; W465-L485 HydrophobicContact CZ3-CB 4.04Å; W465-L485 WeakPolarHBondContact CZ3-O 3.26Å; W465-C487 HydrophobicContact CD2-CB 4.25Å; W465-C487 HydrophobicContact CE3-CB 3.91Å; W465-C487 HydrophobicContact CH2-CB 3.97Å; W465-C487 HydrophobicContact CZ2-CB 4.24Å; W465-C487 HydrophobicContact CZ3-CB 3.77Å; W465-F490 AromaticContact CH2-CE2 3.63Å; W465-F490 HydrophobicContact CH2-CE2 3.63Å; W465-F490 AromaticContact CH2-CZ 3.84Å; W465-F490 HydrophobicContact CH2-CZ 3.84Å; W465-F490 HydrophobicContact CZ2-CZ 4.3Å; W465-F490 HydrophobicContact CZ3-CE2 4.37Å; W465-L492 HydrophobicContact CH2-CD1 3.67Å; W465-L492 HydrophobicContact CH2-CG 3.82Å; W465-L492 HydrophobicContact CZ3-CD1 3.9Å; W465-L492 HydrophobicContact CZ3-CG 3.84Å
466	R	89	Confident	74.2	Confident	179 Å²	179	85.1 Å²	85.1	68%	0.675	43%	0.43	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-101.9	115.3	172.5	-170.4	179.9	-60.3	-178	1.8	110.5	I468 K486	R466-I468 HydrophobicContact CG-CG1 4.31Å; R466-K486 PolarHBondContact N-O 2.85Å; R466-K486 PolarHBondContact O-N 3.26Å
467	L	91.6	Very high	75.8	Confident	47 Å²	47	82.4 Å²	82.4	25%	0.246	42%	0.415	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-76.1	125.6	169.7	174.1	59.4	0	0	0	110.3	I274 Q275 A278 V473 F483 L485	I274-L467 HydrophobicContact CG2-CD1 4.3Å; I274-L467 HydrophobicContact CG2-CD2 4.37Å; Q275-L467 HydrophobicContact CB-CD2 4.27Å; A278-L467 HydrophobicContact CB-CD1 4.1Å; A278-L467 HydrophobicContact CB-CD2 4.06Å; L467-V473 HydrophobicContact CD2-CB 3.89Å; L467-V473 HydrophobicContact CD2-CG1 3.62Å; L467-V473 HydrophobicContact CG-CG1 3.9Å; L467-F483 HydrophobicContact CD1-CB 4.21Å; L467-F483 HydrophobicContact CD1-CD2 3.53Å; L467-F483 HydrophobicContact CD1-CE2 4.25Å; L467-F483 HydrophobicContact CD1-CG 4.2Å; L467-L485 HydrophobicContact CB-CD2 4.12Å; L467-L485 HydrophobicContact CD1-CD2 4.07Å
468	I	92.7	Very high	77.5	Confident	79 Å²	79	79 Å²	79	41%	0.405	40%	0.398	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-122	129	175.9	-55	173.7	0	0	0	107.2	R466 V484 K486	R466-I468 HydrophobicContact CG-CG1 4.31Å; I468-V484 HydrophobicContact CB-CB 4.4Å; I468-V484 PolarHBondContact N-O 3.19Å; I468-V484 PolarHBondContact O-N 3.26Å; I468-K486 HydrophobicContact CD1-CB 4.03Å; I468-K486 HydrophobicContact CD1-CD 4.17Å
469	S	91.7	Very high	79.4	Confident	26 Å²	26	77.1 Å²	77.1	18%	0.182	39%	0.387	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-153.5	141.7	178.5	-174.8	0	0	0	0	108.8	E471	S469-E471 VanDerWaalsContact C-N 3.26Å; S469-E471 WeakPolarHBondContact CB-O 3.32Å; S469-E471 PolarHBondContact OG-N 3.32Å; S469-E471 PolarHBondContact OG-O 3.5Å
470	D	88.7	Confident	81	Confident	166 Å²	166	74.8 Å²	74.8	89%	0.888	40%	0.395	S	S	*	.	S	Bend	trans	-71.8	-26.3	175.4	-57.3	-31.2	0	0	0	111.4
471	E	87.8	Confident	83.1	Confident	61 Å²	61	67.9 Å²	67.9	29%	0.285	37%	0.37	S	S	.	.	S	Bend	trans	-90	155.4	171.6	-61.1	-157.2	154.6	0	0	112.1	I274 S469 V473 R478 I481	I274-E471 HydrophobicContact CD1-CB 3.94Å; S469-E471 VanDerWaalsContact C-N 3.26Å; S469-E471 WeakPolarHBondContact CB-O 3.32Å; S469-E471 PolarHBondContact OG-N 3.32Å; S469-E471 PolarHBondContact OG-O 3.5Å; E471-V473 PolarHBondContact O-N 2.89Å; E471-V473 VanDerWaalsContact O-N 3.12Å; E471-R478 IonicContact OE1-CZ 2.85Å; E471-R478 IonicContact OE1-NE 3.88Å; E471-R478 PolarHBondContact OE1-NE 3.34Å; E471-R478 IonicContact OE1-NH2 2.75Å; E471-R478 PolarHBondContact OE1-NH2 2.98Å; E471-R478 IonicContact OE2-CZ 3.18Å; E471-R478 IonicContact OE2-NE 3.46Å; E471-R478 PolarHBondContact OE2-NE 3.45Å; E471-R478 IonicContact OE2-NH2 3Å; E471-R478 PolarHBondContact OE2-NH2 2.69Å; E471-I481 WeakPolarHBondContact OE2-CD1 3.37Å
472	A	85.8	Confident	85.3	Confident	49 Å²	49	67.3 Å²	67.3	41%	0.405	37%	0.369	S	S	.	.			trans	-58.5	119.4	172.7	0	0	0	0	0	110.9	T474 N475	A472-T474 PolarHBondContact O-N 2.9Å; A472-N475 WeakPolarHBondContact O-CB 3.42Å; A472-N475 VanDerWaalsContact O-CG 3.31Å; A472-N475 PolarHBondContact O-N 3.07Å
473	V	84.8	Confident	87.2	Confident	27 Å²	27	66 Å²	66	16%	0.164	36%	0.36	C	S	.	.	T	Hydrogen-bonded Turn	trans	-57.6	-16	-174.2	-60.6	0	0	0	0	115.5	Q275 L467 E471	Q275-V473 HydrophobicContact CB-CB 4.33Å; Q275-V473 WeakPolarHBondContact CB-O 3.43Å; Q275-V473 PolarHBondContact N-O 3.34Å; L467-V473 HydrophobicContact CD2-CB 3.89Å; L467-V473 HydrophobicContact CD2-CG1 3.62Å; L467-V473 HydrophobicContact CG-CG1 3.9Å; E471-V473 PolarHBondContact O-N 2.89Å; E471-V473 VanDerWaalsContact O-N 3.12Å
474	T	82.2	Confident	88.8	Confident	51 Å²	51	63.7 Å²	63.7	31%	0.313	35%	0.345	S	S	.	.	T	Hydrogen-bonded Turn	trans	-78.2	-17.9	174.1	44.8	0	0	0	0	113.6	A472	A472-T474 PolarHBondContact O-N 2.9Å
475	N	84.4	Confident	89.6	Confident	58 Å²	58	58.7 Å²	58.7	31%	0.31	32%	0.322	S	S	.	.	S	Bend	trans	-67	152.1	178.9	-67.8	-6.9	0	0	0	111.2	S273 I274 A472	S273-N475 CarbonylContact C-O 3.6Å; S273-N475 WeakPolarHBondContact CA-O 3.46Å; S273-N475 WeakPolarHBondContact CB-O 3.47Å; I274-N475 PolarHBondContact N-O 3.48Å; A472-N475 WeakPolarHBondContact O-CB 3.42Å; A472-N475 VanDerWaalsContact O-CG 3.31Å; A472-N475 PolarHBondContact O-N 3.07Å
476	G	85.9	Confident	89.8	Confident	42 Å²	42	62 Å²	62	43%	0.433	34%	0.338	S	S	.	.	B	Isolated β-bridge	trans	-66.2	151	170.8	0	0	0	0	0	111.9	L272	L272-G476 CarbonylContact O-C 3.55Å; L272-G476 WeakPolarHBondContact O-CA 3.49Å
477	L	88.8	Confident	89.6	Confident	8 Å²	8	53.9 Å²	53.9	4%	0.042	31%	0.308	C	S	.	.	P	Polyproline II helix	trans	-54	139.5	168.7	-67.5	178.6	0	0	0	111	F252 L254 L272 I274 A277 F483 V496	F252-L477 HydrophobicContact CB-CD1 4.4Å; F252-L477 HydrophobicContact CD2-CB 3.88Å; F252-L477 HydrophobicContact CD2-CD1 4.13Å; F252-L477 HydrophobicContact CE2-CB 3.88Å; F252-L477 HydrophobicContact CG-CB 4.21Å; F252-L477 HydrophobicContact CG-CD1 4.39Å; F252-L477 HydrophobicContact CZ-CB 4.21Å; F252-L477 WeakPolarHBondContact CZ-O 3.38Å; L254-L477 HydrophobicContact CD1-CD1 4.38Å; L254-L477 HydrophobicContact CD2-CD1 4.42Å; L272-L477 PolarHBondContact O-N 3.06Å; I274-L477 HydrophobicContact CG1-CD2 4.3Å; A277-L477 HydrophobicContact CB-CD1 3.87Å; A277-L477 HydrophobicContact CB-CD2 3.9Å; A277-L477 HydrophobicContact CB-CG 4.14Å; L477-F483 HydrophobicContact CD2-CE1 4.27Å; L477-V496 HydrophobicContact CB-CG1 4.36Å; L477-V496 HydrophobicContact CD2-CG1 4.31Å; L477-V496 HydrophobicContact CD2-CG2 3.95Å
478	R	89.6	Confident	89	Confident	124 Å²	124	57.1 Å²	57.1	47%	0.468	33%	0.325	S	S	.	.			trans	-132.4	162.5	172.8	-60	-174.2	-89.9	-132	0.2	109.1	E471 I481 V496	E471-R478 IonicContact OE1-CZ 2.85Å; E471-R478 IonicContact OE1-NE 3.88Å; E471-R478 PolarHBondContact OE1-NE 3.34Å; E471-R478 IonicContact OE1-NH2 2.75Å; E471-R478 PolarHBondContact OE1-NH2 2.98Å; E471-R478 IonicContact OE2-CZ 3.18Å; E471-R478 IonicContact OE2-NE 3.46Å; E471-R478 PolarHBondContact OE2-NE 3.45Å; E471-R478 IonicContact OE2-NH2 3Å; E471-R478 PolarHBondContact OE2-NH2 2.69Å; R478-I481 HydrophobicContact CB-CD1 3.72Å; R478-I481 HydrophobicContact CB-CG1 3.97Å; R478-I481 HydrophobicContact CG-CD1 4.17Å; R478-I481 VanDerWaalsContact N-CD1 3.34Å; R478-V496 VanDerWaalsContact O-CG1 3.3Å; R478-V496 WeakPolarHBondContact O-CG1 3.38Å
479	D	91.1	Very high	88.2	Confident	103 Å²	103	58.1 Å²	58.1	55%	0.551	33%	0.331	S	S	*	.	T	Hydrogen-bonded Turn	trans	-62.6	139.1	173.6	-166.5	43.1	0	0	0	110.9	I481 K497 K498	D479-I481 VanDerWaalsContact C-N 3.27Å; D479-I481 PolarHBondContact O-N 3.02Å; D479-K497 WeakPolarHBondContact OD1-CA 3.48Å; D479-K498 HydrophobicContact CB-CB 3.95Å; D479-K498 PolarHBondContact OD1-N 3.24Å
480	G	90.4	Very high	87.9	Confident	53 Å²	53	57.9 Å²	57.9	55%	0.546	33%	0.327	S	S	.	.	T	Hydrogen-bonded Turn	trans	76.6	0.1	178.5	0	0	0	0	0	116	V482 V496	G480-V482 PolarHBondContact O-N 3.15Å; G480-V496 WeakPolarHBondContact CA-O 3.21Å; G480-V496 PolarHBondContact N-O 3.43Å
481	I	93.4	Very high	88	Confident	12 Å²	12	51.1 Å²	51.1	6%	0.062	29%	0.293	C	S	.	.			trans	-64.3	133.9	174	-66.8	-176	0	0	0	109.7	I274 E471 R478 D479 F483 V496	I274-I481 HydrophobicContact CD1-CD1 4.14Å; I274-I481 HydrophobicContact CD1-CG2 4.33Å; I274-I481 HydrophobicContact CG1-CD1 4.44Å; E471-I481 WeakPolarHBondContact OE2-CD1 3.37Å; R478-I481 HydrophobicContact CB-CD1 3.72Å; R478-I481 HydrophobicContact CB-CG1 3.97Å; R478-I481 HydrophobicContact CG-CD1 4.17Å; R478-I481 VanDerWaalsContact N-CD1 3.34Å; D479-I481 VanDerWaalsContact C-N 3.27Å; D479-I481 PolarHBondContact O-N 3.02Å; I481-F483 HydrophobicContact CG2-CD1 4.31Å; I481-V496 HydrophobicContact CB-CB 4.22Å; I481-V496 HydrophobicContact CB-CG2 4.16Å; I481-V496 HydrophobicContact CG2-CG2 4.38Å; I481-V496 WeakPolarHBondContact O-CB 3.24Å; I481-V496 WeakPolarHBondContact O-CG2 3.49Å; I481-V496 PolarHBondContact O-N 3.28Å
482	V	94.4	Very high	88.3	Confident	63 Å²	63	48.2 Å²	48.2	38%	0.382	28%	0.279	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-114.3	134.3	164.9	-177	0	0	0	0	108.8	G480 V493 V494 N495	G480-V482 PolarHBondContact O-N 3.15Å; V482-V493 HydrophobicContact CG1-CG1 3.94Å; V482-V494 VanDerWaalsContact CA-O 3.31Å; V482-V494 WeakPolarHBondContact CA-O 3.39Å; V482-N495 HydrophobicContact CG2-CB 4.49Å
483	F	95.4	Very high	88.7	Confident	1 Å²	1	48.4 Å²	48.4	0%	0.004	28%	0.275	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-137.8	156.8	170	67.5	-92.9	0	0	0	110.4	L254 I274 A277 A278 L467 L477 I481 L485 V494 V496	L254-F483 HydrophobicContact CD2-CE1 4Å; L254-F483 HydrophobicContact CD2-CZ 4.09Å; I274-F483 HydrophobicContact CG2-CB 4.02Å; I274-F483 HydrophobicContact CG2-CD1 3.82Å; I274-F483 HydrophobicContact CG2-CD2 4.29Å; I274-F483 HydrophobicContact CG2-CE1 4.3Å; I274-F483 HydrophobicContact CG2-CG 3.8Å; A277-F483 HydrophobicContact CB-CZ 4.34Å; A278-F483 HydrophobicContact CB-CE2 3.92Å; L467-F483 HydrophobicContact CD1-CB 4.21Å; L467-F483 HydrophobicContact CD1-CD2 3.53Å; L467-F483 HydrophobicContact CD1-CE2 4.25Å; L467-F483 HydrophobicContact CD1-CG 4.2Å; L477-F483 HydrophobicContact CD2-CE1 4.27Å; I481-F483 HydrophobicContact CG2-CD1 4.31Å; F483-L485 HydrophobicContact CE2-CD1 4.22Å; F483-L485 HydrophobicContact CE2-CG 4.36Å; F483-V494 HydrophobicContact CD1-CB 4.13Å; F483-V494 HydrophobicContact CD1-CG1 4.34Å; F483-V494 HydrophobicContact CD2-CB 4.02Å; F483-V494 HydrophobicContact CD2-CG2 4.08Å; F483-V494 HydrophobicContact CE1-CB 3.88Å; F483-V494 HydrophobicContact CE1-CG1 3.65Å; F483-V494 HydrophobicContact CE2-CB 3.75Å; F483-V494 HydrophobicContact CE2-CG1 4.09Å; F483-V494 HydrophobicContact CE2-CG2 3.64Å; F483-V494 HydrophobicContact CG-CB 4.21Å; F483-V494 HydrophobicContact CZ-CB 3.69Å; F483-V494 HydrophobicContact CZ-CG1 3.52Å; F483-V494 HydrophobicContact CZ-CG2 3.96Å; F483-V494 PolarHBondContact N-O 3.21Å; F483-V494 PolarHBondContact O-N 3.46Å; F483-V496 HydrophobicContact CD1-CG2 4.21Å; F483-V496 HydrophobicContact CE1-CG2 3.91Å
484	V	95.2	Very high	89.3	Confident	38 Å²	38	47.1 Å²	47.1	23%	0.23	27%	0.268	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-124.4	129.9	-173.4	-177	0	0	0	0	109.7	I468 L492 V493	I468-V484 HydrophobicContact CB-CB 4.4Å; I468-V484 PolarHBondContact N-O 3.19Å; I468-V484 PolarHBondContact O-N 3.26Å; V484-L492 WeakPolarHBondContact CA-O 3.43Å; V484-V493 HydrophobicContact CG2-CG2 4.36Å
485	L	93.2	Very high	89.9	Confident	3 Å²	3	47.2 Å²	47.2	2%	0.016	27%	0.266	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-100.4	110.5	169.3	-69.1	161	0	0	0	107.6	A278 V281 L282 W465 L467 F483 S491 L492 V494	A278-L485 HydrophobicContact CB-CD1 4.25Å; A278-L485 HydrophobicContact CB-CD2 3.78Å; A278-L485 HydrophobicContact CB-CG 4.42Å; V281-L485 HydrophobicContact CB-CD1 4.14Å; V281-L485 HydrophobicContact CG1-CD1 3.72Å; L282-L485 HydrophobicContact CD1-CD2 4.39Å; L282-L485 HydrophobicContact CD2-CB 4.46Å; L282-L485 HydrophobicContact CD2-CD1 3.93Å; L282-L485 HydrophobicContact CG-CD1 4.04Å; W465-L485 HydrophobicContact CE3-CB 3.78Å; W465-L485 HydrophobicContact CZ3-CB 4.04Å; W465-L485 WeakPolarHBondContact CZ3-O 3.26Å; L467-L485 HydrophobicContact CB-CD2 4.12Å; L467-L485 HydrophobicContact CD1-CD2 4.07Å; F483-L485 HydrophobicContact CE2-CD1 4.22Å; F483-L485 HydrophobicContact CE2-CG 4.36Å; L485-S491 CarbonylContact O-C 3.55Å; L485-S491 WeakPolarHBondContact O-CA 3.4Å; L485-S491 WeakPolarHBondContact O-CB 3.48Å; L485-L492 HydrophobicContact CB-CB 4.25Å; L485-L492 PolarHBondContact N-O 3.43Å; L485-L492 PolarHBondContact O-N 2.85Å; L485-V494 HydrophobicContact CD1-CG2 4.38Å
486	K	90.1	Very high	90.4	Very high	113 Å²	113	44.5 Å²	44.5	49%	0.491	25%	0.251	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-99.8	122	-177.6	-176.2	168.5	-178	176.6	0	110.5	R466 I468	R466-K486 PolarHBondContact N-O 2.85Å; R466-K486 PolarHBondContact O-N 3.26Å; I468-K486 HydrophobicContact CD1-CB 4.03Å; I468-K486 HydrophobicContact CD1-CD 4.17Å
487	C	84.8	Confident	90.8	Very high	7 Å²	7	48.1 Å²	48.1	5%	0.047	26%	0.255	C	S	.	.			trans	-96.2	-177.1	163.9	-167.1	0	0	0	0	108.4	W465 F490	W465-C487 HydrophobicContact CD2-CB 4.25Å; W465-C487 HydrophobicContact CE3-CB 3.91Å; W465-C487 HydrophobicContact CH2-CB 3.97Å; W465-C487 HydrophobicContact CZ2-CB 4.24Å; W465-C487 HydrophobicContact CZ3-CB 3.77Å; C487-F490 CarbonylContact C-O 3.53Å; C487-F490 WeakPolarHBondContact CB-O 3.46Å; C487-F490 PolarHBondContact N-O 3.17Å
488	L	77.9	Confident	90.9	Very high	115 Å²	115	53.5 Å²	53.5	60%	0.602	28%	0.278	S	S	*	.	S	Bend	trans	-63.7	-51.6	177.5	-68.7	168.6	0	0	0	111.9	L461	L461-L488 HydrophobicContact CB-CD1 3.96Å; L461-L488 HydrophobicContact CD2-CD1 4.48Å
489	D	76	Confident	90.9	Very high	100 Å²	100	50 Å²	50	54%	0.535	27%	0.269	S	S	.	.	S	Bend	trans	-89.9	-24.5	-170	-59.8	-25.8	0	0	0	114.4	Y292	Y292-D489 HydrophobicContact CE1-CB 3.96Å
490	F	85.6	Confident	90.8	Very high	21 Å²	21	49.8 Å²	49.8	9%	0.092	27%	0.273	C	S	.	.			trans	-156.2	176.7	-173.6	67.4	-86.7	0	0	0	111.8	R258 T260 Y285 Y292 W465 C487 L492	R258-F490 HydrophobicContact CG-CD2 3.74Å; R258-F490 HydrophobicContact CG-CE2 4.18Å; R258-F490 HydrophobicContact CG-CG 4.43Å; T260-F490 HydrophobicContact CG2-CB 3.51Å; Y285-F490 HydrophobicContact CE1-CZ 4.2Å; Y285-F490 HydrophobicContact CE2-CE2 4.27Å; Y285-F490 AromaticContact CZ-CE2 3.92Å; Y285-F490 AromaticContact CZ-CZ 3.75Å; Y285-F490 WeakPolarHBondContact OH-CZ 3.26Å; Y292-F490 AromaticContact CD1-CD1 3.57Å; Y292-F490 HydrophobicContact CD1-CD1 3.57Å; Y292-F490 AromaticContact CD1-CE1 3.88Å; Y292-F490 HydrophobicContact CD1-CE1 3.88Å; Y292-F490 HydrophobicContact CD1-CG 4.49Å; Y292-F490 AromaticContact CE1-CD1 3.91Å; Y292-F490 HydrophobicContact CE1-CD1 3.91Å; Y292-F490 AromaticContact CG-CD1 3.97Å; Y292-F490 HydrophobicContact CG-CD1 3.97Å; Y292-F490 HydrophobicContact CG-CE1 4.15Å; W465-F490 AromaticContact CH2-CE2 3.63Å; W465-F490 HydrophobicContact CH2-CE2 3.63Å; W465-F490 AromaticContact CH2-CZ 3.84Å; W465-F490 HydrophobicContact CH2-CZ 3.84Å; W465-F490 HydrophobicContact CZ2-CZ 4.3Å; W465-F490 HydrophobicContact CZ3-CE2 4.37Å; C487-F490 CarbonylContact C-O 3.53Å; C487-F490 WeakPolarHBondContact CB-O 3.46Å; C487-F490 PolarHBondContact N-O 3.17Å; F490-L492 HydrophobicContact CD2-CD2 4.39Å; F490-L492 HydrophobicContact CE2-CD2 3.99Å; F490-L492 HydrophobicContact CE2-CG 4.35Å
491	S	91.4	Very high	90.4	Very high	24 Å²	24	56.3 Å²	56.3	17%	0.168	29%	0.286	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-132.7	153	173.5	58	0	0	0	0	112.2	S259 L485	S259-S491 WeakPolarHBondContact CB-O 3.38Å; S259-S491 VanDerWaalsContact CB-OG 3.32Å; S259-S491 WeakPolarHBondContact CB-OG 3.37Å; S259-S491 PolarHBondContact N-O 3.33Å; S259-S491 PolarHBondContact OG-N 2.95Å; S259-S491 PolarHBondContact OG-O 3.3Å; S259-S491 PolarHBondContact OG-OG 3.49Å; L485-S491 CarbonylContact O-C 3.55Å; L485-S491 WeakPolarHBondContact O-CA 3.4Å; L485-S491 WeakPolarHBondContact O-CB 3.48Å
492	L	93.2	Very high	90	Very high	0 Å²	0	62.2 Å²	62.2	0%	0	32%	0.317	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-100.6	116.2	165.9	-54.1	174.4	0	0	0	107.7	V256 V257 R258 V281 L282 Y285 W465 V484 L485 F490	V256-L492 HydrophobicContact CG1-CB 4.04Å; V256-L492 HydrophobicContact CG1-CD1 4.37Å; V256-L492 HydrophobicContact CG1-CD2 4.46Å; V257-L492 CarbonylContact O-C 3.56Å; V257-L492 WeakPolarHBondContact O-CA 3.36Å; R258-L492 HydrophobicContact CB-CD2 3.88Å; R258-L492 HydrophobicContact CG-CD2 4.27Å; V281-L492 HydrophobicContact CG1-CD1 4.47Å; L282-L492 HydrophobicContact CD2-CD1 4.28Å; Y285-L492 HydrophobicContact CD1-CD1 4.42Å; Y285-L492 HydrophobicContact CD2-CD1 3.57Å; Y285-L492 HydrophobicContact CD2-CD2 3.72Å; Y285-L492 HydrophobicContact CD2-CG 4.26Å; Y285-L492 HydrophobicContact CE2-CD1 4.25Å; Y285-L492 HydrophobicContact CE2-CD2 3.72Å; Y285-L492 HydrophobicContact CG-CD1 3.69Å; W465-L492 HydrophobicContact CH2-CD1 3.67Å; W465-L492 HydrophobicContact CH2-CG 3.82Å; W465-L492 HydrophobicContact CZ3-CD1 3.9Å; W465-L492 HydrophobicContact CZ3-CG 3.84Å; V484-L492 WeakPolarHBondContact CA-O 3.43Å; L485-L492 HydrophobicContact CB-CB 4.25Å; L485-L492 PolarHBondContact N-O 3.43Å; L485-L492 PolarHBondContact O-N 2.85Å; F490-L492 HydrophobicContact CD2-CD2 4.39Å; F490-L492 HydrophobicContact CE2-CD2 3.99Å; F490-L492 HydrophobicContact CE2-CG 4.35Å
493	V	95.4	Very high	89.6	Confident	54 Å²	54	64.6 Å²	64.6	33%	0.327	33%	0.331	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-89.3	123.9	172.7	-177.3	0	0	0	0	107.4	V257 V482 V484	V257-V493 PolarHBondContact N-O 3Å; V257-V493 PolarHBondContact O-N 3.21Å; V482-V493 HydrophobicContact CG1-CG1 3.94Å; V484-V493 HydrophobicContact CG2-CG2 4.36Å
494	V	96.1	Very high	89.4	Confident	0 Å²	0	71.1 Å²	71.1	0%	0	37%	0.365	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-114.8	116.6	-176.4	-169.8	0	0	0	0	109.2	L254 Q255 V256 V281 V482 F483 L485	L254-V494 HydrophobicContact CB-CG1 3.9Å; L254-V494 HydrophobicContact CD2-CG1 3.65Å; L254-V494 HydrophobicContact CG-CG1 4.29Å; Q255-V494 WeakPolarHBondContact O-CA 3.36Å; V256-V494 HydrophobicContact CG1-CG2 4.35Å; V256-V494 HydrophobicContact CG2-CG1 4.03Å; V256-V494 HydrophobicContact CG2-CG2 4.16Å; V281-V494 HydrophobicContact CG1-CG2 4.09Å; V281-V494 HydrophobicContact CG2-CG1 4.4Å; V482-V494 VanDerWaalsContact CA-O 3.31Å; V482-V494 WeakPolarHBondContact CA-O 3.39Å; F483-V494 HydrophobicContact CD1-CB 4.13Å; F483-V494 HydrophobicContact CD1-CG1 4.34Å; F483-V494 HydrophobicContact CD2-CB 4.02Å; F483-V494 HydrophobicContact CD2-CG2 4.08Å; F483-V494 HydrophobicContact CE1-CB 3.88Å; F483-V494 HydrophobicContact CE1-CG1 3.65Å; F483-V494 HydrophobicContact CE2-CB 3.75Å; F483-V494 HydrophobicContact CE2-CG1 4.09Å; F483-V494 HydrophobicContact CE2-CG2 3.64Å; F483-V494 HydrophobicContact CG-CB 4.21Å; F483-V494 HydrophobicContact CZ-CB 3.69Å; F483-V494 HydrophobicContact CZ-CG1 3.52Å; F483-V494 HydrophobicContact CZ-CG2 3.96Å; F483-V494 PolarHBondContact N-O 3.21Å; F483-V494 PolarHBondContact O-N 3.46Å; L485-V494 HydrophobicContact CD1-CG2 4.38Å
495	N	95.6	Very high	89.1	Confident	53 Å²	53	74.4 Å²	74.4	28%	0.283	39%	0.39	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-106	122.5	176.9	-174.9	-29.2	0	0	0	109.5	L254 Q255 V482	L254-N495 CarbonylContact C-O 3.48Å; L254-N495 WeakPolarHBondContact CA-O 3.36Å; Q255-N495 HydrophobicContact CB-CB 4.45Å; Q255-N495 PolarHBondContact N-O 3.02Å; Q255-N495 PolarHBondContact O-N 2.83Å; V482-N495 HydrophobicContact CG2-CB 4.49Å
496	V	95.3	Very high	88.9	Confident	0 Å²	0	82.7 Å²	82.7	0%	0	43%	0.428	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-99	121.7	-175	-174.3	0	0	0	0	109.7	F252 L254 L477 R478 G480 I481 F483	F252-V496 HydrophobicContact CB-CG1 4.04Å; F252-V496 HydrophobicContact CD1-CG1 3.86Å; F252-V496 HydrophobicContact CG-CG1 4.14Å; L254-V496 HydrophobicContact CD2-CG2 3.99Å; L254-V496 HydrophobicContact CG-CG2 4.18Å; L477-V496 HydrophobicContact CB-CG1 4.36Å; L477-V496 HydrophobicContact CD2-CG1 4.31Å; L477-V496 HydrophobicContact CD2-CG2 3.95Å; R478-V496 VanDerWaalsContact O-CG1 3.3Å; R478-V496 WeakPolarHBondContact O-CG1 3.38Å; G480-V496 WeakPolarHBondContact CA-O 3.21Å; G480-V496 PolarHBondContact N-O 3.43Å; I481-V496 HydrophobicContact CB-CB 4.22Å; I481-V496 HydrophobicContact CB-CG2 4.16Å; I481-V496 HydrophobicContact CG2-CG2 4.38Å; I481-V496 WeakPolarHBondContact O-CB 3.24Å; I481-V496 WeakPolarHBondContact O-CG2 3.49Å; I481-V496 PolarHBondContact O-N 3.28Å; F483-V496 HydrophobicContact CD1-CG2 4.21Å; F483-V496 HydrophobicContact CE1-CG2 3.91Å
497	K	93.6	Very high	88.9	Confident	119 Å²	119	85.6 Å²	85.6	52%	0.517	44%	0.444	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-119.3	140.5	171.6	-66.2	-172.7	177.2	-178	0	110.8	F252 T253 D479	F252-K497 CarbonylContact C-O 3.57Å; F252-K497 VanDerWaalsContact CA-O 3.28Å; F252-K497 WeakPolarHBondContact CA-O 3.46Å; T253-K497 PolarHBondContact N-O 3.14Å; T253-K497 PolarHBondContact O-N 3.12Å; D479-K497 WeakPolarHBondContact OD1-CA 3.48Å
498	K	92.3	Very high	89	Confident	120 Å²	120	93.9 Å²	93.9	52%	0.522	48%	0.479	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-73.8	136.5	172.1	-172	179	177.3	-174.4	0	109.9	M251 F252 D479	M251-K498 HydrophobicContact CG-CG 4.28Å; F252-K498 HydrophobicContact CD1-CB 4.26Å; F252-K498 HydrophobicContact CE1-CB 4.28Å; F252-K498 HydrophobicContact CE1-CG 4.4Å; D479-K498 HydrophobicContact CB-CB 3.95Å; D479-K498 PolarHBondContact OD1-N 3.24Å
499	I	88.9	Confident	89.3	Confident	52 Å²	52	93 Å²	93	27%	0.267	48%	0.475	S	S	.	.	P	Polyproline II helix	trans	-66.1	128.3	173.6	-63.5	172.6	0	0	0	108	P250 M251 T253	P250-I499 HydrophobicContact CB-CD1 4.11Å; M251-I499 PolarHBondContact O-N 3.4Å; T253-I499 WeakPolarHBondContact OG1-CG1 3.44Å
500	P	87.7	Confident	89.5	Confident	98 Å²	98	91.5 Å²	91.5	64%	0.636	47%	0.466	S	S	*	.	P	Polyproline II helix	trans	-67.2	152.1	179.4	28.7	-35.3	0	0	0	111.1	I502	P500-I502 PolarHBondContact O-N 3.1Å
501	F	82.7	Confident	89.3	Confident	189 Å²	189	95 Å²	95	83%	0.829	49%	0.491	S	S	*	.			trans	-73.5	114.6	170.5	-177.4	-111	0	0	0	109.2	V503	F501-V503 HydrophobicContact CD1-CG2 3.78Å; F501-V503 HydrophobicContact CE1-CG2 3.46Å; F501-V503 VanDerWaalsContact CE1-CG2 3.46Å; F501-V503 HydrophobicContact CZ-CG2 4.41Å
502	I	85.5	Confident	88.5	Confident	136 Å²	136	100.3 Å²	100.3	70%	0.697	51%	0.511	S	S	*	.	P	Polyproline II helix	trans	-93.8	117.3	-178.9	-57.6	174.7	0	0	0	108.3	P500	P500-I502 PolarHBondContact O-N 3.1Å
503	V	86.5	Confident	87.4	Confident	113 Å²	113	104 Å²	104	69%	0.685	54%	0.537	S	S	*	.	P	Polyproline II helix	trans	-95.9	117.1	168.4	-179.9	0	0	0	0	107.8	F501	F501-V503 HydrophobicContact CD1-CG2 3.78Å; F501-V503 HydrophobicContact CE1-CG2 3.46Å; F501-V503 VanDerWaalsContact CE1-CG2 3.46Å; F501-V503 HydrophobicContact CZ-CG2 4.41Å
504	L	89.8	Confident	86.1	Confident	138 Å²	138	107.2 Å²	107.2	72%	0.723	55%	0.548	S	S	*	.	P	Polyproline II helix	trans	-95	123.3	170.6	-174.8	66.9	0	0	0	108.7
505	S	89.6	Confident	84.9	Confident	107 Å²	107	114.8 Å²	114.8	75%	0.748	58%	0.581	S	S	*	*	P	Polyproline II helix	trans	-100.4	125.2	168.4	55	0	0	0	0	109.3
506	E	89.9	Confident	83.8	Confident	177 Å²	177	121.5 Å²	121.5	83%	0.827	61%	0.608	S	S	*	*	P	Polyproline II helix	trans	-97.3	127.8	174.8	-65.7	179.8	-170.8	0	0	109.9
507	E	89.2	Confident	82.5	Confident	175 Å²	175	127.5 Å²	127.5	82%	0.818	65%	0.645	S	S	*	*			trans	-117.1	119.3	173.4	-173.7	176.3	178.9	0	0	109.1	I509	E507-I509 PolarHBondContact O-N 3.2Å
508	F	86.2	Confident	81.1	Confident	180 Å²	180	128.7 Å²	128.7	79%	0.789	66%	0.656	S	S	*	*			trans	-85.7	106.6	176.3	179.9	-95.8	0	0	0	110.3	D510	F508-D510 HydrophobicContact CE1-CB 4.49Å; F508-D510 PolarHBondContact O-N 3.38Å
509	I	84.3	Confident	79.7	Confident	98 Å²	98	133.5 Å²	133.5	50%	0.503	67%	0.671	S	S	.	*			trans	-80.3	110.1	173.9	-58.4	176.3	0	0	0	108.7	E507 S513	E507-I509 PolarHBondContact O-N 3.2Å; I509-S513 WeakPolarHBondContact CG2-OG 3.45Å
510	D	81.3	Confident	78.7	Confident	68 Å²	68	138 Å²	138	36%	0.364	69%	0.694	S	S	.	*			trans	-57.6	126.4	172.8	179.1	-11.7	0	0	0	109.3	F508 K512 S513	F508-D510 HydrophobicContact CE1-CB 4.49Å; F508-D510 PolarHBondContact O-N 3.38Å; D510-K512 PolarHBondContact O-N 2.83Å; D510-K512 WeakPolarHBondContact OD1-CB 3.38Å; D510-K512 WeakPolarHBondContact OD1-CG 3.38Å; D510-K512 PolarHBondContact OD1-N 2.89Å; D510-S513 VanDerWaalsContact O-CB 3.24Å; D510-S513 WeakPolarHBondContact O-CB 3.22Å; D510-S513 PolarHBondContact O-N 2.92Å; D510-S513 PolarHBondContact O-OG 3.29Å
511	P	80.2	Confident	77.5	Confident	93 Å²	93	141 Å²	141	60%	0.604	70%	0.7	S	S	*	*	G	3₁₀ helix	trans	-57.7	-16.6	176.7	22.4	-34.4	0	0	0	114.4	S513	P511-S513 VanDerWaalsContact C-N 3.28Å; P511-S513 PolarHBondContact O-N 3.15Å
512	K	74.8	Confident	76.5	Confident	137 Å²	137	137.3 Å²	137.3	60%	0.596	70%	0.697	S	S	*	*	G	3₁₀ helix	trans	-70.1	-20.9	170.7	-63.9	171.9	-169.9	160.1	0	113.5	D510 H514 K515	D510-K512 PolarHBondContact O-N 2.83Å; D510-K512 WeakPolarHBondContact OD1-CB 3.38Å; D510-K512 WeakPolarHBondContact OD1-CG 3.38Å; D510-K512 PolarHBondContact OD1-N 2.89Å; K512-H514 PolarHBondContact O-N 3.33Å; K512-K515 WeakPolarHBondContact O-CB 3.39Å; K512-K515 WeakPolarHBondContact O-CG 3.44Å; K512-K515 PolarHBondContact O-N 3.03Å
513	S	71	Confident	75.3	Confident	78 Å²	78	138.4 Å²	138.4	55%	0.545	70%	0.7	S	S	.	*	G	3₁₀ helix	trans	-66.8	-22.8	178.6	69.3	0	0	0	0	112.8	I509 D510 P511 K515	I509-S513 WeakPolarHBondContact CG2-OG 3.45Å; D510-S513 VanDerWaalsContact O-CB 3.24Å; D510-S513 WeakPolarHBondContact O-CB 3.22Å; D510-S513 PolarHBondContact O-N 2.92Å; D510-S513 PolarHBondContact O-OG 3.29Å; P511-S513 VanDerWaalsContact C-N 3.28Å; P511-S513 PolarHBondContact O-N 3.15Å; S513-K515 PolarHBondContact O-N 2.79Å
514	H	67.3	Low	73.9	Confident	120 Å²	120	139.3 Å²	139.3	56%	0.556	71%	0.706	S	S	*	*	G	3₁₀ helix	trans	-80.4	9.3	175	-57.8	-49.9	0	0	0	114.2	K512 F516	K512-H514 PolarHBondContact O-N 3.33Å; H514-F516 WeakPolarHBondContact O-CD2 3.35Å; H514-F516 PolarHBondContact O-N 3.2Å
515	K	71.1	Confident	72.1	Confident	159 Å²	159	138.1 Å²	138.1	69%	0.691	71%	0.709	S	S	*	*			trans	-81.2	95.8	176.7	-70.5	-174.9	177.4	-170.6	0	111.3	K512 S513 V517	K512-K515 WeakPolarHBondContact O-CB 3.39Å; K512-K515 WeakPolarHBondContact O-CG 3.44Å; K512-K515 PolarHBondContact O-N 3.03Å; S513-K515 PolarHBondContact O-N 2.79Å; K515-V517 PolarHBondContact O-N 3.22Å
516	F	72.2	Confident	70	Confident	195 Å²	195	143.4 Å²	143.4	86%	0.855	74%	0.736	S	S	*	*			trans	-65.8	117.8	171.4	-59	-81.2	0	0	0	111.2	H514 L518	H514-F516 WeakPolarHBondContact O-CD2 3.35Å; H514-F516 PolarHBondContact O-N 3.2Å; F516-L518 PolarHBondContact O-N 3.36Å
517	V	68.5	Low	69	Low	126 Å²	126	141.8 Å²	141.8	76%	0.764	73%	0.732	S	S	*	*			trans	-81.1	105.4	170.7	178.5	0	0	0	0	108.7	K515 R519	K515-V517 PolarHBondContact O-N 3.22Å; V517-R519 HydrophobicContact CG1-CG 4.29Å; V517-R519 PolarHBondContact O-N 3.19Å
518	L	63.7	Low	68	Low	143 Å²	143	140 Å²	140	75%	0.749	73%	0.727	S	S	*	*			trans	-75.1	89.5	177.6	-154.4	156.7	0	0	0	109.2	F516 L520	F516-L518 PolarHBondContact O-N 3.36Å; L518-L520 HydrophobicContact CD2-CD1 3.6Å; L518-L520 HydrophobicContact CD2-CG 4.07Å; L518-L520 PolarHBondContact O-N 3.1Å; L518-L520 VanDerWaalsContact O-N 3.1Å
519	R	63.6	Low	67	Low	222 Å²	222	137.8 Å²	137.8	84%	0.838	72%	0.724	S	S	*	*			trans	-72.3	97.3	172.8	-72.5	-173.5	175.8	178.5	-1	109.3	V517 Q521	V517-R519 HydrophobicContact CG1-CG 4.29Å; V517-R519 PolarHBondContact O-N 3.19Å; R519-Q521 PolarHBondContact O-N 2.72Å
520	L	66.9	Low	65.9	Low	146 Å²	146	140.1 Å²	140.1	76%	0.764	74%	0.737	S	S	*	*			trans	-66.2	112.2	160.6	-73.6	92.3	0	0	0	107.8	L518 S522	L518-L520 HydrophobicContact CD2-CD1 3.6Å; L518-L520 HydrophobicContact CD2-CG 4.07Å; L518-L520 PolarHBondContact O-N 3.1Å; L518-L520 VanDerWaalsContact O-N 3.1Å; L520-S522 PolarHBondContact O-N 2.97Å
521	Q	62.5	Low	65	Low	160 Å²	160	144.6 Å²	144.6	75%	0.748	76%	0.76	S	S	*	*			trans	-68.9	110.6	162	-73.4	178.9	-77.2	0	0	107.4	R519 E523	R519-Q521 PolarHBondContact O-N 2.72Å; Q521-E523 PolarHBondContact O-N 2.91Å
522	S	63	Low	64	Low	112 Å²	112	148.1 Å²	148.1	78%	0.783	77%	0.77	S	S	*	*			trans	-76.8	55.6	173.7	60.1	0	0	0	0	111.1	L520 T524	L520-S522 PolarHBondContact O-N 2.97Å; S522-T524 PolarHBondContact O-N 3.33Å
523	E	60.1	Low	63.2	Low	160 Å²	160	148.9 Å²	148.9	75%	0.748	78%	0.783	S	S	*	*			trans	-91.8	49.3	170.8	-72.8	-176.4	-159.1	0	0	110.9	Q521	Q521-E523 PolarHBondContact O-N 2.91Å
524	T	56.3	Low	62.6	Low	132 Å²	132	154.3 Å²	154.3	81%	0.81	80%	0.801	S	S	*	*			trans	-136.2	88.4	157.6	54.5	0	0	0	0	107.5	S522	S522-T524 PolarHBondContact O-N 3.33Å
525	S	52.7	Low	62.2	Low	112 Å²	112	157.2 Å²	157.2	78%	0.783	82%	0.822	S	S	*	*			trans	-79.1	122.3	173	53.3	0	0	0	0	110.7
526	V	45.8	Very low	61.4	Low	219 Å²	219	157 Å²	157	100%	1.327	83%	0.834	S	S	*	*			trans	63.5	0	166.8	-170.7	0	0	0	0	115.7

Retrieved 526 of 526 residues in 636.5 ms (Link to these results)

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