A0A061IQH2_CRIGR Loading...

Homeodomain-only protein

Atypical homeodomain protein which does not bind DNA and is required to modulate cardiac growth and development. Acts via its interaction with SRF, thereby modulating the expression of SRF-dependent cardiac-specific genes and cardiac development. Prevents SRF-dependent transcription either by inhibiting SRF binding to DNA or by recruiting histone deacetylase (HDAC) proteins that prevent transcription by SRF. Overexpression causes cardiac hypertrophy. Acts as a co-chaperone for HSPA1A and HSPA1B chaperone proteins and assists in chaperone-mediated protein refolding.

AlphaFold DB , UniProt , Accession A0A061IQH2, Species CRIGR (Cricetulus griseus, Chinese hamster), Gene Hopx, Length 73 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M40Very low63.6Low245 Ų245114.5 Ų114.5100%1.20770%0.704SS**  0119.10-72-160176.400106.9A3M1-A3 PolarHBondContact O-N 3.32Å
2S44.7Very low65.9Low118 Ų118115.1 Ų115.183%0.82570%0.7SS**  trans-78.1105.2-171-51.20000109.9E4S2-E4 PolarHBondContact O-N 3.12Å
3A49.7Very low67.9Low105 Ų105108.5 Ų108.587%0.86866%0.657SS**  trans-83.676.5162.900000107.6M1M1-A3 PolarHBondContact O-N 3.32Å
4E58.3Low69.6Low174 Ų174103.2 Ų103.281%0.81363%0.625SS**  trans-105.982.2174.1-164.9177.1116.400107.9S2S2-E4 PolarHBondContact O-N 3.12Å
5T46.4Very low71.2Confident88 Ų88105 Ų10554%0.5462%0.623SS.*  trans-14583.2165.350.10000110.8S7T5-S7 PolarHBondContact O-N 3.42Å
6A58.5Low72.5Confident105 Ų105101.5 Ų101.587%0.86860%0.6SS**SBendtrans-67.675.6155.900000109.4
7S65.8Low73.7Confident120 Ų12095.5 Ų95.584%0.83957%0.565SS**SBendtrans172.765.6159.7-79.10000111.6T5T5-S7 PolarHBondContact O-N 3.42Å
8G70.3Confident74.8Confident35 Ų3593.6 Ų93.636%0.36155%0.549SS..SBendtrans70174.116900000116.1
9P85.8Confident75.7Confident39 Ų3996.5 Ų96.525%0.25355%0.551SS.*  trans-67.9143.5179.526.8-32.6000111.8Q13 V14 L17 L42 W50P9-Q13 HydrophobicContact CB-CB 3.92Å; P9-V14 HydrophobicContact CB-CG2 4.02Å; P9-V14 HydrophobicContact CG-CG2 3.76Å; P9-L17 HydrophobicContact CB-CD1 4.21Å; P9-L17 HydrophobicContact CG-CD1 4.25Å; P9-L42 HydrophobicContact CB-CD1 3.99Å; P9-L42 HydrophobicContact CB-CD2 4.39Å; P9-W50 HydrophobicContact CG-CG 4.5Å
10T90.6Very high76.5Confident66 Ų6692.4 Ų92.441%0.40553%0.527SS..  trans-69.6166.3174.154.30000112.1D12 Q13 V14T10-D12 PolarHBondContact O-N 2.97Å; T10-Q13 WeakPolarHBondContact O-CB 3.45Å; T10-Q13 PolarHBondContact O-N 3.2Å; T10-Q13 VanDerWaalsContact OG1-CD 3.23Å; T10-Q13 WeakPolarHBondContact OG1-CG 3.43Å; T10-Q13 PolarHBondContact OG1-OE1 3.36Å; T10-V14 WeakPolarHBondContact O-CG2 3.43Å; T10-V14 PolarHBondContact O-N 2.92Å
11E89.8Confident77.2Confident164 Ų16488.1 Ų88.177%0.76650%0.503SS*.Hα-helixtrans-59-46.3-175.6-167.1147.370.800112.8Q13 V14 E15E11-Q13 VanDerWaalsContact C-N 3.27Å; E11-Q13 PolarHBondContact O-N 3.25Å; E11-V14 WeakPolarHBondContact O-CB 3.47Å; E11-V14 PolarHBondContact O-N 3.35Å; E11-V14 VanDerWaalsContact O-N 3.1Å; E11-E15 PolarHBondContact O-N 3.46Å
12D90.8Very high79.6Confident122 Ų12280.6 Ų80.665%0.65247%0.467SS*.Hα-helixtrans-53.6-43.4171.9-83.6-99.9000112.5T10 E15 I16T10-D12 PolarHBondContact O-N 2.97Å; D12-E15 PolarHBondContact O-N 3.5Å; D12-I16 WeakPolarHBondContact O-CG1 3.47Å; D12-I16 PolarHBondContact O-N 3.3Å
13Q92.1Very high81.6Confident30 Ų3082.2 Ų82.214%0.1446%0.46CS..Hα-helixtrans-68.6-40.2179.5-62.8176.7-5200111.2P9 T10 E11 E15 I16 L17 A40 L42P9-Q13 HydrophobicContact CB-CB 3.92Å; T10-Q13 WeakPolarHBondContact O-CB 3.45Å; T10-Q13 PolarHBondContact O-N 3.2Å; T10-Q13 VanDerWaalsContact OG1-CD 3.23Å; T10-Q13 WeakPolarHBondContact OG1-CG 3.43Å; T10-Q13 PolarHBondContact OG1-OE1 3.36Å; E11-Q13 VanDerWaalsContact C-N 3.27Å; E11-Q13 PolarHBondContact O-N 3.25Å; Q13-E15 VanDerWaalsContact C-N 3.34Å; Q13-I16 PolarHBondContact O-N 3.46Å; Q13-L17 WeakPolarHBondContact O-CB 3.46Å; Q13-L17 WeakPolarHBondContact O-CG 3.45Å; Q13-L17 PolarHBondContact O-N 2.82Å; Q13-A40 HydrophobicContact CB-CB 4.46Å; Q13-A40 VanDerWaalsContact CG-O 3.28Å; Q13-A40 WeakPolarHBondContact CG-O 3.4Å; Q13-A40 PolarHBondContact NE2-O 3Å; Q13-L42 HydrophobicContact CB-CD1 4.2Å; Q13-L42 VanDerWaalsContact NE2-CD2 3.27Å
14V91.9Very high83.4Confident34 Ų3481.1 Ų81.121%0.20644%0.442CS..Hα-helixtrans-62.8-41.1175.5173.60000110.6P9 T10 E11 I16 L17 E18 W50P9-V14 HydrophobicContact CB-CG2 4.02Å; P9-V14 HydrophobicContact CG-CG2 3.76Å; T10-V14 WeakPolarHBondContact O-CG2 3.43Å; T10-V14 PolarHBondContact O-N 2.92Å; E11-V14 WeakPolarHBondContact O-CB 3.47Å; E11-V14 PolarHBondContact O-N 3.35Å; E11-V14 VanDerWaalsContact O-N 3.1Å; V14-I16 VanDerWaalsContact C-N 3.35Å; V14-I16 PolarHBondContact O-N 3.34Å; V14-L17 PolarHBondContact O-N 2.95Å; V14-E18 HydrophobicContact CG1-CG 4.12Å; V14-E18 WeakPolarHBondContact O-CB 3.5Å; V14-E18 WeakPolarHBondContact O-CG 3.23Å; V14-E18 PolarHBondContact O-N 3.25Å; V14-W50 HydrophobicContact CG1-CZ2 4.22Å
15E92.9Very high84.5Confident130 Ų13076.3 Ų76.361%0.60742%0.422SS*.Hα-helixtrans-59.1-45.4175.6-75.8-167.883.300111.8E11 D12 Q13 E18 Y19E11-E15 PolarHBondContact O-N 3.46Å; D12-E15 PolarHBondContact O-N 3.5Å; Q13-E15 VanDerWaalsContact C-N 3.34Å; E15-E18 PolarHBondContact O-N 2.93Å; E15-Y19 VanDerWaalsContact O-CB 3.3Å; E15-Y19 WeakPolarHBondContact O-CB 3.46Å; E15-Y19 PolarHBondContact O-N 3.02Å
16I93.3Very high86.4Confident49 Ų4974.3 Ų74.325%0.25141%0.406SS..Hα-helixtrans-62.2-46176.5-63.3163.5000110.6D12 Q13 V14 Y19 N20 E39 A40D12-I16 WeakPolarHBondContact O-CG1 3.47Å; D12-I16 PolarHBondContact O-N 3.3Å; Q13-I16 PolarHBondContact O-N 3.46Å; V14-I16 VanDerWaalsContact C-N 3.35Å; V14-I16 PolarHBondContact O-N 3.34Å; I16-Y19 PolarHBondContact O-N 3.24Å; I16-N20 WeakPolarHBondContact O-CB 3.39Å; I16-N20 PolarHBondContact O-N 3.17Å; I16-N20 PolarHBondContact O-ND2 2.96Å; I16-E39 HydrophobicContact CG2-CB 4.39Å; I16-E39 HydrophobicContact CG2-CG 4.02Å; I16-A40 HydrophobicContact CB-CB 4.37Å; I16-A40 HydrophobicContact CG2-CB 4.09Å
17L92.3Very high87.7Confident0 Ų074.4 Ų74.40%039%0.388CS..Hα-helixtrans-63.6-43.5179-70.1168.3000112P9 Q13 V14 N20 F21 I36 L42 T47 W50 F51P9-L17 HydrophobicContact CB-CD1 4.21Å; P9-L17 HydrophobicContact CG-CD1 4.25Å; Q13-L17 WeakPolarHBondContact O-CB 3.46Å; Q13-L17 WeakPolarHBondContact O-CG 3.45Å; Q13-L17 PolarHBondContact O-N 2.82Å; V14-L17 PolarHBondContact O-N 2.95Å; L17-N20 PolarHBondContact O-N 3.18Å; L17-F21 VanDerWaalsContact O-CB 3.23Å; L17-F21 WeakPolarHBondContact O-CB 3.3Å; L17-F21 PolarHBondContact O-N 3.32Å; L17-I36 HydrophobicContact CD2-CG2 3.84Å; L17-L42 HydrophobicContact CD1-CD1 3.7Å; L17-L42 HydrophobicContact CD2-CD1 4.41Å; L17-L42 HydrophobicContact CG-CD1 4.33Å; L17-T47 HydrophobicContact CD2-CG2 3.69Å; L17-W50 HydrophobicContact CB-CD2 3.97Å; L17-W50 HydrophobicContact CB-CE3 3.78Å; L17-W50 HydrophobicContact CB-CH2 3.8Å; L17-W50 HydrophobicContact CB-CZ2 3.97Å; L17-W50 HydrophobicContact CB-CZ3 3.71Å; L17-W50 HydrophobicContact CD1-CB 4.24Å; L17-W50 HydrophobicContact CD1-CD2 3.77Å; L17-W50 HydrophobicContact CD1-CE3 4.24Å; L17-W50 HydrophobicContact CD1-CG 3.75Å; L17-W50 HydrophobicContact CD2-CE3 4.41Å; L17-W50 HydrophobicContact CG-CD2 4.38Å; L17-W50 HydrophobicContact CG-CE3 4.39Å; L17-F51 HydrophobicContact CD2-CD2 4.26Å; L17-F51 HydrophobicContact CD2-CE2 3.79Å
18E92.7Very high88.7Confident61 Ų6169.7 Ų69.729%0.28536%0.355SS..Hα-helixtrans-67-40.8177.8-78-154.673.100112.6V14 E15 F21 N22 W50 R54V14-E18 HydrophobicContact CG1-CG 4.12Å; V14-E18 WeakPolarHBondContact O-CB 3.5Å; V14-E18 WeakPolarHBondContact O-CG 3.23Å; V14-E18 PolarHBondContact O-N 3.25Å; E15-E18 PolarHBondContact O-N 2.93Å; E18-F21 PolarHBondContact O-N 2.84Å; E18-N22 WeakPolarHBondContact O-CB 3.44Å; E18-N22 PolarHBondContact O-N 3Å; E18-N22 PolarHBondContact O-ND2 3.39Å; E18-W50 HydrophobicContact CB-CH2 4.31Å; E18-W50 HydrophobicContact CG-CH2 3.58Å; E18-W50 HydrophobicContact CG-CZ2 3.58Å; E18-R54 IonicContact OE1-CZ 3.3Å; E18-R54 VanDerWaalsContact OE1-CZ 3.3Å; E18-R54 IonicContact OE1-NE 3.61Å; E18-R54 IonicContact OE1-NH2 2.63Å; E18-R54 PolarHBondContact OE1-NH2 3.48Å
19Y93.1Very high89.6Confident148 Ų14872.9 Ų72.958%0.5836%0.363SS*.Hα-helixtrans-58.4-51.7174.2-178-89000109.9E15 I16 F21 N22 K23E15-Y19 VanDerWaalsContact O-CB 3.3Å; E15-Y19 WeakPolarHBondContact O-CB 3.46Å; E15-Y19 PolarHBondContact O-N 3.02Å; I16-Y19 PolarHBondContact O-N 3.24Å; Y19-F21 PolarHBondContact O-N 3.49Å; Y19-N22 PolarHBondContact O-N 2.89Å; Y19-K23 HydrophobicContact CD1-CB 4.41Å; Y19-K23 HydrophobicContact CD1-CG 4.41Å; Y19-K23 HydrophobicContact CD2-CG 4.01Å; Y19-K23 HydrophobicContact CE1-CB 4.16Å; Y19-K23 HydrophobicContact CE1-CG 4.23Å; Y19-K23 HydrophobicContact CE2-CG 3.84Å; Y19-K23 HydrophobicContact CG-CG 4.3Å; Y19-K23 WeakPolarHBondContact O-CB 3.4Å; Y19-K23 WeakPolarHBondContact O-CG 3.49Å; Y19-K23 PolarHBondContact O-N 3.43Å
20N91.8Very high89.8Confident15 Ų1575.6 Ų75.68%0.0838%0.381CS..Hα-helixtrans-62.9-41.4178.9-80.9-75.5000112.4I16 L17 N22 V24 N25 I36 F51I16-N20 WeakPolarHBondContact O-CB 3.39Å; I16-N20 PolarHBondContact O-N 3.17Å; I16-N20 PolarHBondContact O-ND2 2.96Å; L17-N20 PolarHBondContact O-N 3.18Å; N20-N22 PolarHBondContact O-N 3.37Å; N20-V24 HydrophobicContact CB-CG2 4.46Å; N20-V24 WeakPolarHBondContact O-CA 3.28Å; N20-V24 VanDerWaalsContact O-CB 3.25Å; N20-V24 WeakPolarHBondContact O-CB 3.2Å; N20-V24 PolarHBondContact O-N 3.42Å; N20-V24 WeakPolarHBondContact OD1-CG2 3.4Å; N20-N25 PolarHBondContact O-N 2.87Å; N20-I36 HydrophobicContact CB-CD1 3.85Å; N20-I36 HydrophobicContact CB-CG1 3.96Å; N20-I36 HydrophobicContact CB-CG2 4.09Å; N20-F51 HydrophobicContact CB-CZ 4.38Å
21F91.2Very high89.8Confident2 Ų277.5 Ų77.51%0.00939%0.393CS..Hα-helixtrans-63.5-38.1177.8-177.6-93.9000113.3L17 E18 Y19 K26 W50 F51 R54 L55 W58L17-F21 VanDerWaalsContact O-CB 3.23Å; L17-F21 WeakPolarHBondContact O-CB 3.3Å; L17-F21 PolarHBondContact O-N 3.32Å; E18-F21 PolarHBondContact O-N 2.84Å; Y19-F21 PolarHBondContact O-N 3.49Å; F21-K26 HydrophobicContact CD1-CG 4.39Å; F21-K26 HydrophobicContact CD2-CB 4.44Å; F21-K26 HydrophobicContact CE1-CD 4.32Å; F21-K26 HydrophobicContact CE1-CG 3.98Å; F21-K26 HydrophobicContact CE2-CB 3.89Å; F21-K26 HydrophobicContact CE2-CG 4.11Å; F21-K26 HydrophobicContact CZ-CB 3.98Å; F21-K26 HydrophobicContact CZ-CD 4.22Å; F21-K26 HydrophobicContact CZ-CG 3.8Å; F21-K26 WeakPolarHBondContact O-CG 3.23Å; F21-W50 HydrophobicContact CB-CH2 4.34Å; F21-W50 HydrophobicContact CB-CZ3 4.01Å; F21-W50 HydrophobicContact CD2-CZ3 4.42Å; F21-W50 HydrophobicContact CG-CZ3 4.32Å; F21-F51 HydrophobicContact CB-CE1 3.96Å; F21-F51 HydrophobicContact CB-CZ 4.1Å; F21-F51 AromaticContact CD2-CD1 3.6Å; F21-F51 HydrophobicContact CD2-CD1 3.6Å; F21-F51 AromaticContact CD2-CE1 3.64Å; F21-F51 HydrophobicContact CD2-CE1 3.64Å; F21-F51 HydrophobicContact CD2-CG 4.41Å; F21-F51 HydrophobicContact CD2-CZ 4.49Å; F21-F51 HydrophobicContact CE2-CD1 4.29Å; F21-F51 HydrophobicContact CG-CE1 4.3Å; F21-R54 HydrophobicContact CD1-CG 3.87Å; F21-R54 HydrophobicContact CD2-CB 4.46Å; F21-R54 HydrophobicContact CD2-CG 4.26Å; F21-R54 HydrophobicContact CE1-CG 3.85Å; F21-R54 HydrophobicContact CE2-CB 4.33Å; F21-R54 HydrophobicContact CE2-CG 4.25Å; F21-R54 HydrophobicContact CG-CG 4.09Å; F21-R54 HydrophobicContact CZ-CB 4.47Å; F21-R54 HydrophobicContact CZ-CG 4.06Å; F21-L55 HydrophobicContact CE2-CB 4.1Å; F21-L55 HydrophobicContact CE2-CD1 4.27Å; F21-L55 HydrophobicContact CZ-CB 4.29Å; F21-L55 HydrophobicContact CZ-CD1 4.16Å; F21-W58 HydrophobicContact CE1-CB 4.04Å; F21-W58 HydrophobicContact CE1-CG 4.14Å; F21-W58 HydrophobicContact CZ-CB 4.03Å; F21-W58 HydrophobicContact CZ-CG 4.32Å
22N89.1Confident89.9Confident87 Ų8771.7 Ų71.747%0.46537%0.368SS..Hα-helixtrans-90-31.6-177.9-72.4-53.5000113.7E18 Y19 N20E18-N22 WeakPolarHBondContact O-CB 3.44Å; E18-N22 PolarHBondContact O-N 3Å; E18-N22 PolarHBondContact O-ND2 3.39Å; Y19-N22 PolarHBondContact O-N 2.89Å; N20-N22 PolarHBondContact O-N 3.37Å
23K88.3Confident90Very high153 Ų15366.6 Ų66.667%0.66534%0.341SS*.Hα-helixtrans-99.8-35.8-174.2-63.2-65.2-171.9179.40113.9Y19Y19-K23 HydrophobicContact CD1-CB 4.41Å; Y19-K23 HydrophobicContact CD1-CG 4.41Å; Y19-K23 HydrophobicContact CD2-CG 4.01Å; Y19-K23 HydrophobicContact CE1-CB 4.16Å; Y19-K23 HydrophobicContact CE1-CG 4.23Å; Y19-K23 HydrophobicContact CE2-CG 3.84Å; Y19-K23 HydrophobicContact CG-CG 4.3Å; Y19-K23 WeakPolarHBondContact O-CB 3.4Å; Y19-K23 WeakPolarHBondContact O-CG 3.49Å; Y19-K23 PolarHBondContact O-N 3.43Å
24V86.6Confident90Very high82 Ų8267.8 Ų67.850%0.49735%0.352SS..THydrogen-bonded Turntrans-92.6-73.6-175.8-178.10000109.9N20 T32N20-V24 HydrophobicContact CB-CG2 4.46Å; N20-V24 WeakPolarHBondContact O-CA 3.28Å; N20-V24 VanDerWaalsContact O-CB 3.25Å; N20-V24 WeakPolarHBondContact O-CB 3.2Å; N20-V24 PolarHBondContact O-N 3.42Å; N20-V24 WeakPolarHBondContact OD1-CG2 3.4Å; V24-T32 HydrophobicContact CG1-CG2 4.19Å
25N82Confident90.1Very high73 Ų7371.9 Ų71.939%0.3937%0.372SS..  trans-163.3141.5-180-165.2-4.2000110.7N20 H27N20-N25 PolarHBondContact O-N 2.87Å; N25-H27 VanDerWaalsContact C-N 3.25Å; N25-H27 PolarHBondContact ND2-O 3.41Å; N25-H27 PolarHBondContact O-N 3.35Å; N25-H27 PolarHBondContact OD1-N 2.9Å; N25-H27 VanDerWaalsContact OD1-N 3.15Å
26K86.4Confident90.1Very high46 Ų4665.9 Ų65.920%0.234%0.344CS..SBendtrans-74.8-19.1174.1-62.8178.4-174.6-73.20112.4F21 L55 W58F21-K26 HydrophobicContact CD1-CG 4.39Å; F21-K26 HydrophobicContact CD2-CB 4.44Å; F21-K26 HydrophobicContact CE1-CD 4.32Å; F21-K26 HydrophobicContact CE1-CG 3.98Å; F21-K26 HydrophobicContact CE2-CB 3.89Å; F21-K26 HydrophobicContact CE2-CG 4.11Å; F21-K26 HydrophobicContact CZ-CB 3.98Å; F21-K26 HydrophobicContact CZ-CD 4.22Å; F21-K26 HydrophobicContact CZ-CG 3.8Å; F21-K26 WeakPolarHBondContact O-CG 3.23Å; K26-L55 HydrophobicContact CB-CD1 4.1Å; K26-W58 HydrophobicContact CD-CD2 3.75Å; K26-W58 HydrophobicContact CD-CE3 3.86Å; K26-W58 HydrophobicContact CD-CG 4.48Å; K26-W58 HydrophobicContact CD-CH2 3.79Å; K26-W58 HydrophobicContact CD-CZ2 3.67Å; K26-W58 HydrophobicContact CD-CZ3 3.88Å
27H85.4Confident90Very high106 Ų10663.7 Ų63.749%0.49133%0.333SS..SBendtrans-125.674.2176.5-76.2-87.1000110.4N25 D29 L55N25-H27 VanDerWaalsContact C-N 3.25Å; N25-H27 PolarHBondContact ND2-O 3.41Å; N25-H27 PolarHBondContact O-N 3.35Å; N25-H27 PolarHBondContact OD1-N 2.9Å; N25-H27 VanDerWaalsContact OD1-N 3.15Å; H27-D29 PolarHBondContact O-N 2.85Å; H27-L55 WeakPolarHBondContact CE1-CD2 3.38Å; H27-L55 WeakPolarHBondContact NE2-CD2 3.41Å
28P85.8Confident90Very high22 Ų2267.3 Ų67.314%0.14336%0.364CS..  trans-65.8135177.628.6-34.9000110.9T32 L33 I36 F51P28-T32 HydrophobicContact CB-CG2 3.89Å; P28-L33 HydrophobicContact CB-CB 4.4Å; P28-L33 HydrophobicContact CG-CB 4.43Å; P28-L33 HydrophobicContact CG-CD1 4.35Å; P28-I36 HydrophobicContact CB-CD1 4.15Å; P28-F51 VanDerWaalsContact CD-CD1 3.45Å; P28-F51 HydrophobicContact CG-CD1 3.59Å; P28-F51 HydrophobicContact CG-CE1 3.53Å; P28-F51 HydrophobicContact CG-CG 4.24Å; P28-F51 HydrophobicContact CG-CZ 4.13Å
29D90.7Very high90Very high102 Ų10270.7 Ų70.755%0.54538%0.379SS..  trans-60.4157.3166.3-65.1-82.1000111H27 T31 T32 L33H27-D29 PolarHBondContact O-N 2.85Å; D29-T31 PolarHBondContact O-N 3.23Å; D29-T31 VanDerWaalsContact O-N 3.12Å; D29-T32 WeakPolarHBondContact O-CB 3.23Å; D29-T32 PolarHBondContact O-N 2.92Å; D29-L33 WeakPolarHBondContact O-CB 3.25Å; D29-L33 PolarHBondContact O-N 3.42Å
30P89.1Confident89.8Confident96 Ų9664 Ų6462%0.62336%0.355SS*.Hα-helixtrans-52.7-37.9-178.917.5-31.3000113.2L33 C34P30-L33 PolarHBondContact O-N 2.94Å; P30-C34 WeakPolarHBondContact O-CB 3.46Å; P30-C34 PolarHBondContact O-N 2.93Å
31T91.7Very high89.8Confident105 Ų10566.3 Ų66.364%0.64438%0.382SS*.Hα-helixtrans-62.6-47.6175.2-510000112.2D29 L33 C34 L35D29-T31 PolarHBondContact O-N 3.23Å; D29-T31 VanDerWaalsContact O-N 3.12Å; T31-L33 VanDerWaalsContact C-N 3.32Å; T31-L33 PolarHBondContact O-N 2.88Å; T31-C34 PolarHBondContact O-N 3.44Å; T31-L35 WeakPolarHBondContact O-CG 3.49Å; T31-L35 PolarHBondContact O-N 3.45Å
32T91.3Very high89.8Confident42 Ų4267.3 Ų67.326%0.25839%0.387SS..Hα-helixtrans-65.2-39.7178.2-53.30000110.9V24 P28 D29 C34 L35 I36V24-T32 HydrophobicContact CG1-CG2 4.19Å; P28-T32 HydrophobicContact CB-CG2 3.89Å; D29-T32 WeakPolarHBondContact O-CB 3.23Å; D29-T32 PolarHBondContact O-N 2.92Å; T32-C34 VanDerWaalsContact C-N 3.33Å; T32-C34 PolarHBondContact O-N 3.03Å; T32-L35 PolarHBondContact O-N 3.34Å; T32-I36 HydrophobicContact CG2-CD1 3.91Å; T32-I36 WeakPolarHBondContact O-CD1 3.34Å; T32-I36 VanDerWaalsContact O-CG1 3.23Å; T32-I36 WeakPolarHBondContact O-CG1 3.39Å; T32-I36 PolarHBondContact O-N 2.97Å
33L92.1Very high89.8Confident16 Ų1667 Ų678%0.08439%0.388CS..Hα-helixtrans-62.6-40.5177.6-171.7144.9000111.9P28 D29 P30 T31 I36 A37 E44 T47 Q48P28-L33 HydrophobicContact CB-CB 4.4Å; P28-L33 HydrophobicContact CG-CB 4.43Å; P28-L33 HydrophobicContact CG-CD1 4.35Å; D29-L33 WeakPolarHBondContact O-CB 3.25Å; D29-L33 PolarHBondContact O-N 3.42Å; P30-L33 PolarHBondContact O-N 2.94Å; T31-L33 VanDerWaalsContact C-N 3.32Å; T31-L33 PolarHBondContact O-N 2.88Å; L33-I36 PolarHBondContact O-N 3.19Å; L33-A37 VanDerWaalsContact O-CB 3.3Å; L33-A37 WeakPolarHBondContact O-CB 3.35Å; L33-A37 PolarHBondContact O-N 2.85Å; L33-E44 HydrophobicContact CD2-CB 3.7Å; L33-E44 HydrophobicContact CD2-CG 4.05Å; L33-E44 WeakPolarHBondContact CD2-O 3.31Å; L33-T47 HydrophobicContact CD2-CG2 4.36Å; L33-T47 HydrophobicContact CG-CG2 3.95Å; L33-Q48 HydrophobicContact CD1-CB 3.81Å; L33-Q48 HydrophobicContact CD1-CG 4.03Å; L33-Q48 HydrophobicContact CD2-CB 4.47Å
34C92.8Very high90Very high55 Ų5564.5 Ų64.537%0.37238%0.379SS..Hα-helixtrans-61.8-43.2174.5-1740000111.9P30 T31 T32 A37 A38 E44P30-C34 WeakPolarHBondContact O-CB 3.46Å; P30-C34 PolarHBondContact O-N 2.93Å; T31-C34 PolarHBondContact O-N 3.44Å; T32-C34 VanDerWaalsContact C-N 3.33Å; T32-C34 PolarHBondContact O-N 3.03Å; C34-A37 PolarHBondContact O-N 2.84Å; C34-A38 WeakPolarHBondContact O-CB 3.17Å; C34-A38 PolarHBondContact O-N 3.47Å; C34-E44 HydrophobicContact CB-CG 4.27Å
35L93.3Very high90.1Very high119 Ų11968 Ų6862%0.62339%0.39SS*.Hα-helixtrans-62.1-44.8175.8-65.8172.5000111.9T31 T32 A38 E39T31-L35 WeakPolarHBondContact O-CG 3.49Å; T31-L35 PolarHBondContact O-N 3.45Å; T32-L35 PolarHBondContact O-N 3.34Å; L35-A38 PolarHBondContact O-N 2.87Å; L35-E39 WeakPolarHBondContact O-CB 3.44Å; L35-E39 PolarHBondContact O-N 3.1Å
36I92.4Very high90.5Very high4 Ų468.2 Ų68.22%0.02139%0.389CS..Hα-helixtrans-65-41.5178.1-62161.8000110.9L17 N20 P28 T32 L33 E39 A40 T47 F51L17-I36 HydrophobicContact CD2-CG2 3.84Å; N20-I36 HydrophobicContact CB-CD1 3.85Å; N20-I36 HydrophobicContact CB-CG1 3.96Å; N20-I36 HydrophobicContact CB-CG2 4.09Å; P28-I36 HydrophobicContact CB-CD1 4.15Å; T32-I36 HydrophobicContact CG2-CD1 3.91Å; T32-I36 WeakPolarHBondContact O-CD1 3.34Å; T32-I36 VanDerWaalsContact O-CG1 3.23Å; T32-I36 WeakPolarHBondContact O-CG1 3.39Å; T32-I36 PolarHBondContact O-N 2.97Å; L33-I36 PolarHBondContact O-N 3.19Å; I36-E39 PolarHBondContact O-N 3.28Å; I36-A40 WeakPolarHBondContact O-CB 3.43Å; I36-A40 PolarHBondContact O-N 3.25Å; I36-T47 HydrophobicContact CB-CG2 4.45Å; I36-T47 HydrophobicContact CG2-CG2 4.12Å; I36-F51 HydrophobicContact CD1-CE2 4.43Å; I36-F51 HydrophobicContact CD1-CZ 3.95Å; I36-F51 HydrophobicContact CG2-CE2 4.22Å
37A91.7Very high90.8Very high3 Ų366 Ų663%0.02538%0.379CS..Hα-helixtrans-61.8-44.8176.500000111L33 C34 E39 A40 G41 L42 E44 T47L33-A37 VanDerWaalsContact O-CB 3.3Å; L33-A37 WeakPolarHBondContact O-CB 3.35Å; L33-A37 PolarHBondContact O-N 2.85Å; C34-A37 PolarHBondContact O-N 2.84Å; A37-E39 VanDerWaalsContact C-N 3.34Å; A37-E39 PolarHBondContact O-N 3.05Å; A37-A40 PolarHBondContact O-N 3.43Å; A37-G41 CarbonylContact O-C 3.59Å; A37-G41 PolarHBondContact O-N 2.94Å; A37-L42 CarbonylContact C-O 3.42Å; A37-L42 WeakPolarHBondContact CB-O 3.18Å; A37-L42 PolarHBondContact O-N 3.39Å; A37-L42 VanDerWaalsContact O-O 3.08Å; A37-E44 HydrophobicContact CB-CG 4.28Å; A37-T47 WeakPolarHBondContact CA-OG1 3.3Å; A37-T47 HydrophobicContact CB-CG2 4.49Å; A37-T47 WeakPolarHBondContact CB-OG1 3.43Å
38A93.1Very high91.1Very high77 Ų7765.1 Ų65.164%0.63638%0.375SS*.Hα-helixtrans-62.1-40.617500000112.5C34 L35 G41C34-A38 WeakPolarHBondContact O-CB 3.17Å; C34-A38 PolarHBondContact O-N 3.47Å; L35-A38 PolarHBondContact O-N 2.87Å; A38-G41 PolarHBondContact O-N 2.85Å
39E92.1Very high91.3Very high132 Ų13270.4 Ų70.462%0.61740%0.396SS*.Hα-helixtrans-68.2-40.8178.8-170.7158.572.500112.5I16 L35 I36 A37 G41I16-E39 HydrophobicContact CG2-CB 4.39Å; I16-E39 HydrophobicContact CG2-CG 4.02Å; L35-E39 WeakPolarHBondContact O-CB 3.44Å; L35-E39 PolarHBondContact O-N 3.1Å; I36-E39 PolarHBondContact O-N 3.28Å; A37-E39 VanDerWaalsContact C-N 3.34Å; A37-E39 PolarHBondContact O-N 3.05Å; E39-G41 PolarHBondContact O-N 3.43Å
40A90.1Very high91.4Very high7 Ų766.8 Ų66.86%0.05838%0.375CS..Hα-helixtrans-77.7-6173.900000113.2Q13 I16 I36 A37 L42Q13-A40 HydrophobicContact CB-CB 4.46Å; Q13-A40 VanDerWaalsContact CG-O 3.28Å; Q13-A40 WeakPolarHBondContact CG-O 3.4Å; Q13-A40 PolarHBondContact NE2-O 3Å; I16-A40 HydrophobicContact CB-CB 4.37Å; I16-A40 HydrophobicContact CG2-CB 4.09Å; I36-A40 WeakPolarHBondContact O-CB 3.43Å; I36-A40 PolarHBondContact O-N 3.25Å; A37-A40 PolarHBondContact O-N 3.43Å; A40-L42 HydrophobicContact CB-CB 4.41Å; A40-L42 HydrophobicContact CB-CD1 3.91Å; A40-L42 HydrophobicContact CB-CG 4.06Å; A40-L42 PolarHBondContact O-N 3.38Å
41G91.1Very high91.5Very high63 Ų6362.7 Ų62.765%0.64935%0.347SS*.THydrogen-bonded Turntrans61.629.6-172.900000113.4A37 A38 E39A37-G41 CarbonylContact O-C 3.59Å; A37-G41 PolarHBondContact O-N 2.94Å; A38-G41 PolarHBondContact O-N 2.85Å; E39-G41 PolarHBondContact O-N 3.43Å
42L90.3Very high91.4Very high24 Ų2464 Ų6413%0.12634%0.344CS..  trans-106.4167.5177.8-69.3172.5000110.9P9 Q13 L17 A37 A40P9-L42 HydrophobicContact CB-CD1 3.99Å; P9-L42 HydrophobicContact CB-CD2 4.39Å; Q13-L42 HydrophobicContact CB-CD1 4.2Å; Q13-L42 VanDerWaalsContact NE2-CD2 3.27Å; L17-L42 HydrophobicContact CD1-CD1 3.7Å; L17-L42 HydrophobicContact CD2-CD1 4.41Å; L17-L42 HydrophobicContact CG-CD1 4.33Å; A37-L42 CarbonylContact C-O 3.42Å; A37-L42 WeakPolarHBondContact CB-O 3.18Å; A37-L42 PolarHBondContact O-N 3.39Å; A37-L42 VanDerWaalsContact O-O 3.08Å; A40-L42 HydrophobicContact CB-CB 4.41Å; A40-L42 HydrophobicContact CB-CD1 3.91Å; A40-L42 HydrophobicContact CB-CG 4.06Å; A40-L42 PolarHBondContact O-N 3.38Å
43T90.5Very high91.4Very high79 Ų7967.6 Ų67.649%0.48536%0.357SS..  trans-82.5154.3168.464.50000110.8E45 E46 T47T43-E45 PolarHBondContact O-N 3.1Å; T43-E46 PolarHBondContact O-N 3.42Å; T43-E46 WeakPolarHBondContact OG1-CG 3.4Å; T43-E46 PolarHBondContact OG1-N 3.3Å; T43-T47 PolarHBondContact O-N 2.9Å; T43-T47 PolarHBondContact O-OG1 2.81Å
44E90.9Very high91.3Very high102 Ų10271.2 Ų71.248%0.47737%0.37SS..Hα-helixtrans-54.6-38.9175.1-67.7172.189.200111.7L33 C34 A37 Q48L33-E44 HydrophobicContact CD2-CB 3.7Å; L33-E44 HydrophobicContact CD2-CG 4.05Å; L33-E44 WeakPolarHBondContact CD2-O 3.31Å; C34-E44 HydrophobicContact CB-CG 4.27Å; A37-E44 HydrophobicContact CB-CG 4.28Å; E44-Q48 VanDerWaalsContact O-CB 3.23Å; E44-Q48 WeakPolarHBondContact O-CB 3.4Å; E44-Q48 PolarHBondContact O-N 3.15Å
45E90.4Very high91.1Very high154 Ų15469.4 Ų69.472%0.7236%0.357SS*.Hα-helixtrans-63.6-44.6178.9-170.9174.595.500112.2T43 Q48 K49T43-E45 PolarHBondContact O-N 3.1Å; E45-Q48 PolarHBondContact O-N 3.49Å; E45-K49 WeakPolarHBondContact O-CB 3.38Å; E45-K49 PolarHBondContact O-N 3.42Å
46E90.3Very high90.9Very high79 Ų7966 Ų6637%0.36935%0.346SS..Hα-helixtrans-66.6-45.8178.2-72.8-156.9108.600112.2T43 Q48 K49 W50T43-E46 PolarHBondContact O-N 3.42Å; T43-E46 WeakPolarHBondContact OG1-CG 3.4Å; T43-E46 PolarHBondContact OG1-N 3.3Å; E46-Q48 VanDerWaalsContact C-N 3.31Å; E46-Q48 PolarHBondContact O-N 3.44Å; E46-K49 PolarHBondContact O-N 3.23Å; E46-W50 PolarHBondContact O-N 2.94Å
47T91.6Very high90.7Very high0 Ų070.6 Ų70.60%037%0.367CS..Hα-helixtrans-58.1-45.9174.6-65.60000110.4L17 L33 I36 A37 T43 K49 W50 F51L17-T47 HydrophobicContact CD2-CG2 3.69Å; L33-T47 HydrophobicContact CD2-CG2 4.36Å; L33-T47 HydrophobicContact CG-CG2 3.95Å; I36-T47 HydrophobicContact CB-CG2 4.45Å; I36-T47 HydrophobicContact CG2-CG2 4.12Å; A37-T47 WeakPolarHBondContact CA-OG1 3.3Å; A37-T47 HydrophobicContact CB-CG2 4.49Å; A37-T47 WeakPolarHBondContact CB-OG1 3.43Å; T43-T47 PolarHBondContact O-N 2.9Å; T43-T47 PolarHBondContact O-OG1 2.81Å; T47-K49 PolarHBondContact O-N 3.33Å; T47-W50 PolarHBondContact O-N 3.45Å; T47-F51 HydrophobicContact CG2-CD2 3.81Å; T47-F51 HydrophobicContact CG2-CE2 3.89Å; T47-F51 VanDerWaalsContact O-CD2 3.31Å; T47-F51 WeakPolarHBondContact O-CD2 3.39Å; T47-F51 PolarHBondContact O-N 3.4Å
48Q91.2Very high90.5Very high86 Ų8673.5 Ų73.540%0.40238%0.378SS..Hα-helixtrans-62.6-41.9178.6-167.8-174.30.500112.3L33 E44 E45 E46 F51 K52L33-Q48 HydrophobicContact CD1-CB 3.81Å; L33-Q48 HydrophobicContact CD1-CG 4.03Å; L33-Q48 HydrophobicContact CD2-CB 4.47Å; E44-Q48 VanDerWaalsContact O-CB 3.23Å; E44-Q48 WeakPolarHBondContact O-CB 3.4Å; E44-Q48 PolarHBondContact O-N 3.15Å; E45-Q48 PolarHBondContact O-N 3.49Å; E46-Q48 VanDerWaalsContact C-N 3.31Å; E46-Q48 PolarHBondContact O-N 3.44Å; Q48-F51 PolarHBondContact O-N 2.9Å; Q48-K52 WeakPolarHBondContact O-CG 3.36Å; Q48-K52 PolarHBondContact O-N 3.02Å
49K91.1Very high90.1Very high133 Ų13375.6 Ų75.658%0.57837%0.369SS*.Hα-helixtrans-63-44.2177.8-171.2176.7-179.6-178.70111E45 E46 T47 K52 Q53E45-K49 WeakPolarHBondContact O-CB 3.38Å; E45-K49 PolarHBondContact O-N 3.42Å; E46-K49 PolarHBondContact O-N 3.23Å; T47-K49 PolarHBondContact O-N 3.33Å; K49-K52 PolarHBondContact O-N 3.44Å; K49-Q53 WeakPolarHBondContact O-CG 3.25Å; K49-Q53 PolarHBondContact O-N 2.95Å; K49-Q53 VanDerWaalsContact O-N 3.1Å
50W92.1Very high89.7Confident27 Ų2778.3 Ų78.310%0.10237%0.374CS..Hα-helixtrans-62.3-46.8176-172.998.8000111.5P9 V14 L17 E18 F21 E46 T47 K52 Q53 R54P9-W50 HydrophobicContact CG-CG 4.5Å; V14-W50 HydrophobicContact CG1-CZ2 4.22Å; L17-W50 HydrophobicContact CB-CD2 3.97Å; L17-W50 HydrophobicContact CB-CE3 3.78Å; L17-W50 HydrophobicContact CB-CH2 3.8Å; L17-W50 HydrophobicContact CB-CZ2 3.97Å; L17-W50 HydrophobicContact CB-CZ3 3.71Å; L17-W50 HydrophobicContact CD1-CB 4.24Å; L17-W50 HydrophobicContact CD1-CD2 3.77Å; L17-W50 HydrophobicContact CD1-CE3 4.24Å; L17-W50 HydrophobicContact CD1-CG 3.75Å; L17-W50 HydrophobicContact CD2-CE3 4.41Å; L17-W50 HydrophobicContact CG-CD2 4.38Å; L17-W50 HydrophobicContact CG-CE3 4.39Å; E18-W50 HydrophobicContact CB-CH2 4.31Å; E18-W50 HydrophobicContact CG-CH2 3.58Å; E18-W50 HydrophobicContact CG-CZ2 3.58Å; F21-W50 HydrophobicContact CB-CH2 4.34Å; F21-W50 HydrophobicContact CB-CZ3 4.01Å; F21-W50 HydrophobicContact CD2-CZ3 4.42Å; F21-W50 HydrophobicContact CG-CZ3 4.32Å; E46-W50 PolarHBondContact O-N 2.94Å; T47-W50 PolarHBondContact O-N 3.45Å; W50-K52 PolarHBondContact O-N 2.79Å; W50-Q53 PolarHBondContact O-N 3.47Å; W50-Q53 VanDerWaalsContact O-N 3.15Å; W50-R54 HydrophobicContact CD2-CB 4.39Å; W50-R54 HydrophobicContact CE3-CB 3.99Å; W50-R54 HydrophobicContact CH2-CB 3.86Å; W50-R54 HydrophobicContact CH2-CG 3.55Å; W50-R54 HydrophobicContact CZ2-CB 4.28Å; W50-R54 HydrophobicContact CZ2-CG 4.11Å; W50-R54 HydrophobicContact CZ3-CB 3.7Å; W50-R54 HydrophobicContact CZ3-CG 3.81Å; W50-R54 WeakPolarHBondContact O-CB 3.43Å; W50-R54 PolarHBondContact O-N 3.06Å
51F91.6Very high89.2Confident10 Ų1082.8 Ų82.84%0.04440%0.404CS..Hα-helixtrans-59.7-42.9178.2-95.4-103.1000112L17 N20 F21 P28 I36 T47 Q48 Q53 R54 L55L17-F51 HydrophobicContact CD2-CD2 4.26Å; L17-F51 HydrophobicContact CD2-CE2 3.79Å; N20-F51 HydrophobicContact CB-CZ 4.38Å; F21-F51 HydrophobicContact CB-CE1 3.96Å; F21-F51 HydrophobicContact CB-CZ 4.1Å; F21-F51 AromaticContact CD2-CD1 3.6Å; F21-F51 HydrophobicContact CD2-CD1 3.6Å; F21-F51 AromaticContact CD2-CE1 3.64Å; F21-F51 HydrophobicContact CD2-CE1 3.64Å; F21-F51 HydrophobicContact CD2-CG 4.41Å; F21-F51 HydrophobicContact CD2-CZ 4.49Å; F21-F51 HydrophobicContact CE2-CD1 4.29Å; F21-F51 HydrophobicContact CG-CE1 4.3Å; P28-F51 VanDerWaalsContact CD-CD1 3.45Å; P28-F51 HydrophobicContact CG-CD1 3.59Å; P28-F51 HydrophobicContact CG-CE1 3.53Å; P28-F51 HydrophobicContact CG-CG 4.24Å; P28-F51 HydrophobicContact CG-CZ 4.13Å; I36-F51 HydrophobicContact CD1-CE2 4.43Å; I36-F51 HydrophobicContact CD1-CZ 3.95Å; I36-F51 HydrophobicContact CG2-CE2 4.22Å; T47-F51 HydrophobicContact CG2-CD2 3.81Å; T47-F51 HydrophobicContact CG2-CE2 3.89Å; T47-F51 VanDerWaalsContact O-CD2 3.31Å; T47-F51 WeakPolarHBondContact O-CD2 3.39Å; T47-F51 PolarHBondContact O-N 3.4Å; Q48-F51 PolarHBondContact O-N 2.9Å; F51-Q53 PolarHBondContact O-N 2.85Å; F51-R54 PolarHBondContact O-N 3.23Å; F51-L55 WeakPolarHBondContact O-CB 3.46Å; F51-L55 PolarHBondContact O-N 3.15Å
52K89.9Confident88.6Confident132 Ų13285.3 Ų85.357%0.57440%0.399SS*.Hα-helixtrans-60.7-44.1175.3-77.2175.9-179.1169.40112Q48 K49 W50 A56Q48-K52 WeakPolarHBondContact O-CG 3.36Å; Q48-K52 PolarHBondContact O-N 3.02Å; K49-K52 PolarHBondContact O-N 3.44Å; W50-K52 PolarHBondContact O-N 2.79Å; K52-A56 PolarHBondContact O-N 3.09Å; K52-A56 VanDerWaalsContact O-N 3.09Å
53Q90Very high87.5Confident117 Ų11786.9 Ų86.955%0.54742%0.421SS..Hα-helixtrans-66.5-46.7178.1-72.2178-31.300111.7K49 W50 F51 L55 A56 Q57K49-Q53 WeakPolarHBondContact O-CG 3.25Å; K49-Q53 PolarHBondContact O-N 2.95Å; K49-Q53 VanDerWaalsContact O-N 3.1Å; W50-Q53 PolarHBondContact O-N 3.47Å; W50-Q53 VanDerWaalsContact O-N 3.15Å; F51-Q53 PolarHBondContact O-N 2.85Å; Q53-L55 VanDerWaalsContact C-N 3.34Å; Q53-L55 PolarHBondContact O-N 2.63Å; Q53-A56 PolarHBondContact O-N 3.45Å; Q53-Q57 WeakPolarHBondContact O-CG 3.14Å; Q53-Q57 PolarHBondContact O-N 2.81Å
54R90.4Very high86.1Confident92 Ų9287.6 Ų87.635%0.34742%0.422SS..Hα-helixtrans-63.4-40.6178.5-16968.7176.8165.20.1111.6E18 F21 W50 F51 A56 Q57 W58E18-R54 IonicContact OE1-CZ 3.3Å; E18-R54 VanDerWaalsContact OE1-CZ 3.3Å; E18-R54 IonicContact OE1-NE 3.61Å; E18-R54 IonicContact OE1-NH2 2.63Å; E18-R54 PolarHBondContact OE1-NH2 3.48Å; F21-R54 HydrophobicContact CD1-CG 3.87Å; F21-R54 HydrophobicContact CD2-CB 4.46Å; F21-R54 HydrophobicContact CD2-CG 4.26Å; F21-R54 HydrophobicContact CE1-CG 3.85Å; F21-R54 HydrophobicContact CE2-CB 4.33Å; F21-R54 HydrophobicContact CE2-CG 4.25Å; F21-R54 HydrophobicContact CG-CG 4.09Å; F21-R54 HydrophobicContact CZ-CB 4.47Å; F21-R54 HydrophobicContact CZ-CG 4.06Å; W50-R54 HydrophobicContact CD2-CB 4.39Å; W50-R54 HydrophobicContact CE3-CB 3.99Å; W50-R54 HydrophobicContact CH2-CB 3.86Å; W50-R54 HydrophobicContact CH2-CG 3.55Å; W50-R54 HydrophobicContact CZ2-CB 4.28Å; W50-R54 HydrophobicContact CZ2-CG 4.11Å; W50-R54 HydrophobicContact CZ3-CB 3.7Å; W50-R54 HydrophobicContact CZ3-CG 3.81Å; W50-R54 WeakPolarHBondContact O-CB 3.43Å; W50-R54 PolarHBondContact O-N 3.06Å; F51-R54 PolarHBondContact O-N 3.23Å; R54-A56 PolarHBondContact O-N 3.27Å; R54-Q57 PolarHBondContact O-N 3.36Å; R54-W58 WeakPolarHBondContact O-CB 3.38Å; R54-W58 PolarHBondContact O-N 3.49Å
55L89.7Confident84.4Confident18 Ų1886.8 Ų86.89%0.09443%0.425CS..Hα-helixtrans-61.6-42.3174.6-175.671.2000112.2F21 K26 H27 F51 Q53 Q57 W58 R59F21-L55 HydrophobicContact CE2-CB 4.1Å; F21-L55 HydrophobicContact CE2-CD1 4.27Å; F21-L55 HydrophobicContact CZ-CB 4.29Å; F21-L55 HydrophobicContact CZ-CD1 4.16Å; K26-L55 HydrophobicContact CB-CD1 4.1Å; H27-L55 WeakPolarHBondContact CE1-CD2 3.38Å; H27-L55 WeakPolarHBondContact NE2-CD2 3.41Å; F51-L55 WeakPolarHBondContact O-CB 3.46Å; F51-L55 PolarHBondContact O-N 3.15Å; Q53-L55 VanDerWaalsContact C-N 3.34Å; Q53-L55 PolarHBondContact O-N 2.63Å; L55-Q57 VanDerWaalsContact C-N 3.34Å; L55-Q57 PolarHBondContact O-N 2.87Å; L55-W58 HydrophobicContact CD1-CE3 4.14Å; L55-W58 PolarHBondContact O-N 3.38Å; L55-R59 WeakPolarHBondContact O-CB 3.49Å; L55-R59 WeakPolarHBondContact O-CG 3.43Å; L55-R59 PolarHBondContact O-N 3.12Å
56A88.5Confident82.7Confident48 Ų4885 Ų8540%0.39743%0.43SS..Hα-helixtrans-62.8-40.9176.300000112K52 Q53 R54 R60K52-A56 PolarHBondContact O-N 3.09Å; K52-A56 VanDerWaalsContact O-N 3.09Å; Q53-A56 PolarHBondContact O-N 3.45Å; R54-A56 PolarHBondContact O-N 3.27Å; A56-R60 WeakPolarHBondContact O-CG 3.5Å; A56-R60 PolarHBondContact O-N 3.49Å
57Q87.4Confident80.8Confident100 Ų10088.8 Ų88.847%0.46745%0.447SS..Hα-helixtrans-65.6-47.1174.1-65.9-69.610.300111.4Q53 R54 L55 R59 R60 S61Q53-Q57 WeakPolarHBondContact O-CG 3.14Å; Q53-Q57 PolarHBondContact O-N 2.81Å; R54-Q57 PolarHBondContact O-N 3.36Å; L55-Q57 VanDerWaalsContact C-N 3.34Å; L55-Q57 PolarHBondContact O-N 2.87Å; Q57-R59 VanDerWaalsContact C-N 3.33Å; Q57-R59 PolarHBondContact O-N 3.21Å; Q57-R60 WeakPolarHBondContact O-CB 3.36Å; Q57-R60 PolarHBondContact O-N 3.37Å; Q57-R60 VanDerWaalsContact O-N 3.08Å; Q57-S61 PolarHBondContact O-N 2.85Å; Q57-S61 PolarHBondContact O-OG 3.1Å
58W87.8Confident78.7Confident64 Ų6494.4 Ų94.424%0.24249%0.485CS..Hα-helixtrans-59.1-42.7178.2179.275.3000111.8F21 K26 R54 L55 R60 S61 E62 L64F21-W58 HydrophobicContact CE1-CB 4.04Å; F21-W58 HydrophobicContact CE1-CG 4.14Å; F21-W58 HydrophobicContact CZ-CB 4.03Å; F21-W58 HydrophobicContact CZ-CG 4.32Å; K26-W58 HydrophobicContact CD-CD2 3.75Å; K26-W58 HydrophobicContact CD-CE3 3.86Å; K26-W58 HydrophobicContact CD-CG 4.48Å; K26-W58 HydrophobicContact CD-CH2 3.79Å; K26-W58 HydrophobicContact CD-CZ2 3.67Å; K26-W58 HydrophobicContact CD-CZ3 3.88Å; R54-W58 WeakPolarHBondContact O-CB 3.38Å; R54-W58 PolarHBondContact O-N 3.49Å; L55-W58 HydrophobicContact CD1-CE3 4.14Å; L55-W58 PolarHBondContact O-N 3.38Å; W58-R60 VanDerWaalsContact C-N 3.29Å; W58-R60 PolarHBondContact O-N 2.81Å; W58-S61 PolarHBondContact O-N 3.28Å; W58-S61 VanDerWaalsContact O-N 3.1Å; W58-E62 HydrophobicContact CD2-CG 3.69Å; W58-E62 VanDerWaalsContact CE2-CD 3.49Å; W58-E62 HydrophobicContact CE3-CG 4.2Å; W58-E62 HydrophobicContact CG-CG 4.21Å; W58-E62 HydrophobicContact CH2-CG 3.87Å; W58-E62 HydrophobicContact CZ2-CG 3.3Å; W58-E62 WeakPolarHBondContact CZ2-OE2 3.38Å; W58-E62 HydrophobicContact CZ3-CG 4.28Å; W58-E62 VanDerWaalsContact NE1-CG 3.32Å; W58-E62 PolarHBondContact NE1-OE1 3.35Å; W58-E62 VanDerWaalsContact NE1-OE1 3.12Å; W58-E62 WeakPolarHBondContact O-CG 3.41Å; W58-E62 PolarHBondContact O-N 3.34Å; W58-L64 HydrophobicContact CH2-CD1 4.22Å; W58-L64 HydrophobicContact CZ3-CD1 4.01Å
59R85.2Confident76.8Confident120 Ų120101.1 Ų101.145%0.45351%0.507SS..Hα-helixtrans-59.3-38.3175-77.7-174.7-178.1161.81.4112.9L55 Q57 L64L55-R59 WeakPolarHBondContact O-CB 3.49Å; L55-R59 WeakPolarHBondContact O-CG 3.43Å; L55-R59 PolarHBondContact O-N 3.12Å; Q57-R59 VanDerWaalsContact C-N 3.33Å; Q57-R59 PolarHBondContact O-N 3.21Å; R59-L64 PolarHBondContact O-N 3.28Å
60R83.1Confident75.1Confident190 Ų19099.8 Ų99.872%0.71752%0.515SS*.Hα-helixtrans-67.4-41.1174.2-68.8174.2178.3177.4-1.4111.4A56 Q57 W58 G63A56-R60 WeakPolarHBondContact O-CG 3.5Å; A56-R60 PolarHBondContact O-N 3.49Å; Q57-R60 WeakPolarHBondContact O-CB 3.36Å; Q57-R60 PolarHBondContact O-N 3.37Å; Q57-R60 VanDerWaalsContact O-N 3.08Å; W58-R60 VanDerWaalsContact C-N 3.29Å; W58-R60 PolarHBondContact O-N 2.81Å; R60-G63 PolarHBondContact O-N 3.11Å
61S80.3Confident73.4Confident100 Ų100105.2 Ų105.270%0.69955%0.55SS**Hα-helixtrans-70.1-38-179.7-64.10000113.9Q57 W58 G63Q57-S61 PolarHBondContact O-N 2.85Å; Q57-S61 PolarHBondContact O-OG 3.1Å; W58-S61 PolarHBondContact O-N 3.28Å; W58-S61 VanDerWaalsContact O-N 3.1Å; S61-G63 PolarHBondContact O-N 3.08Å
62E79.3Confident71.6Confident116 Ų116110.9 Ų110.954%0.54259%0.586SS.*THydrogen-bonded Turntrans-70.3-6.4175.8-68.5-75.1123.300113.1W58 L64W58-E62 HydrophobicContact CD2-CG 3.69Å; W58-E62 VanDerWaalsContact CE2-CD 3.49Å; W58-E62 HydrophobicContact CE3-CG 4.2Å; W58-E62 HydrophobicContact CG-CG 4.21Å; W58-E62 HydrophobicContact CH2-CG 3.87Å; W58-E62 HydrophobicContact CZ2-CG 3.3Å; W58-E62 WeakPolarHBondContact CZ2-OE2 3.38Å; W58-E62 HydrophobicContact CZ3-CG 4.28Å; W58-E62 VanDerWaalsContact NE1-CG 3.32Å; W58-E62 PolarHBondContact NE1-OE1 3.35Å; W58-E62 VanDerWaalsContact NE1-OE1 3.12Å; W58-E62 WeakPolarHBondContact O-CG 3.41Å; W58-E62 PolarHBondContact O-N 3.34Å; E62-L64 HydrophobicContact CB-CD1 4.1Å; E62-L64 HydrophobicContact CB-CG 4.19Å; E62-L64 PolarHBondContact O-N 2.94Å
63G66.3Low69.8Low57 Ų57115 Ų11559%0.58861%0.614SS**THydrogen-bonded Turntrans66.417.8-176.600000113.2R60 S61 P65R60-G63 PolarHBondContact O-N 3.11Å; S61-G63 PolarHBondContact O-N 3.08Å; G63-P65 WeakPolarHBondContact O-CD 3.41Å
64L61.8Low68.8Low95 Ų95114.9 Ų114.950%0.49762%0.617SS.*  trans-63.8107.2171.1-78.6161.6000107.3W58 R59 E62 S66W58-L64 HydrophobicContact CH2-CD1 4.22Å; W58-L64 HydrophobicContact CZ3-CD1 4.01Å; R59-L64 PolarHBondContact O-N 3.28Å; E62-L64 HydrophobicContact CB-CD1 4.1Å; E62-L64 HydrophobicContact CB-CG 4.19Å; E62-L64 PolarHBondContact O-N 2.94Å; L64-S66 PolarHBondContact O-N 3.19Å
65P55.4Low67.7Low84 Ų84116.1 Ų116.155%0.54563%0.631SS.*  trans-68.2133.8-175.731.3-33.8000107.9G63 E67G63-P65 WeakPolarHBondContact O-CD 3.41Å; P65-E67 WeakPolarHBondContact CB-O 3.12Å; P65-E67 PolarHBondContact O-N 3.36Å; P65-E67 VanDerWaalsContact O-N 3.11Å
66S53.4Low66.5Low117 Ų117121.5 Ų121.582%0.81866%0.661SS**SBendtrans-65.5-10176.6-57.10000113.1L64L64-S66 PolarHBondContact O-N 3.19Å
67E50.3Low65.2Low158 Ų158125.8 Ų125.874%0.73868%0.677SS**SBendtrans-149.2128.7172-66.8-79.465.700106.5P65 R69P65-E67 WeakPolarHBondContact CB-O 3.12Å; P65-E67 PolarHBondContact O-N 3.36Å; P65-E67 VanDerWaalsContact O-N 3.11Å; E67-R69 PolarHBondContact O-N 2.96Å
68C48Very low63.8Low118 Ų118127.4 Ų127.480%0.79769%0.69SS**  trans-46.8102.8164.1-89.90000108.8S70C68-S70 VanDerWaalsContact C-N 3.28Å; C68-S70 PolarHBondContact O-N 2.81Å
69R52.3Low62.2Low228 Ų228131.7 Ų131.786%0.8672%0.72SS**  trans-69.1100.3161.7-68.3-174.3176.5-160.1-1.3104.7E67 V71E67-R69 PolarHBondContact O-N 2.96Å; R69-V71 PolarHBondContact O-N 3Å
70S54.2Low60.6Low105 Ų105132.5 Ų132.573%0.73474%0.739SS**  trans-41.7115.8171.1-58.70000108.6C68 T72C68-S70 VanDerWaalsContact C-N 3.28Å; C68-S70 PolarHBondContact O-N 2.81Å; S70-T72 VanDerWaalsContact C-N 3.26Å; S70-T72 PolarHBondContact O-N 3.05Å
71V56.8Low58.8Low140 Ų140128.1 Ų128.185%0.84874%0.741SS**  trans-74.990.6171-174.70000105.7R69R69-V71 PolarHBondContact O-N 3Å
72T53.3Low57Low130 Ų130130.4 Ų130.480%0.79874%0.744SS**  trans-114.591154.1-32.90000105.2S70S70-T72 VanDerWaalsContact C-N 3.26Å; S70-T72 PolarHBondContact O-N 3.05Å
73D53.4Low55Low217 Ų217131.7 Ų131.7100%1.1676%0.762SS**  trans-580154.8167-119000109.3

Retrieved 73 of 73 residues in 49.5 ms (Link to these results)

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