A0A061IR51_CRIGR Loading...

Tryptophan 2,3-dioxygenase

Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.

AlphaFold DB , UniProt , Accession A0A061IR51, Species CRIGR (Cricetulus griseus, Chinese hamster), Gene Tdo2, Length 407 aa.

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	33	Very low	29.1	Very low	240 Å²	240	133.5 Å²	133.5	100%	1.182	81%	0.812	S	S	*	*				0	102.8	0	-68	-163.9	-99.8	0	0	106.2
2	S	29.2	Very low	29	Very low	129 Å²	129	128.7 Å²	128.7	90%	0.902	81%	0.809	S	S	*	*				55.6	119.1	91.1	-177.8	0	0	0	0	110.6
3	G	24.7	Very low	29.2	Very low	68 Å²	68	135.6 Å²	135.6	70%	0.701	81%	0.813	S	S	*	*			cis	171.8	155.9	9.5	0	0	0	0	0	107.7
4	C	29.9	Very low	29.2	Very low	117 Å²	117	134 Å²	134	79%	0.791	81%	0.811	S	S	*	*			trans	-62.6	161.1	163.8	-140.5	0	0	0	0	109.6
5	P	38.1	Very low	29.4	Very low	110 Å²	110	136.4 Å²	136.4	71%	0.714	82%	0.816	S	S	*	*				-155.8	153.8	79.2	36.5	-14.9	0	0	0	118.5
6	F	27.7	Very low	29.8	Very low	179 Å²	179	139.4 Å²	139.4	79%	0.785	82%	0.816	S	S	*	*			trans	35.7	137.5	135.9	-75.5	-102.9	0	0	0	120.2
7	L	28.4	Very low	30.2	Very low	158 Å²	158	143.6 Å²	143.6	83%	0.827	82%	0.821	S	S	*	*			cis	-169.4	145.8	46.2	-105.3	122.9	0	0	0	106.1
8	G	25.4	Very low	30.2	Very low	69 Å²	69	144.4 Å²	144.4	71%	0.711	82%	0.822	S	S	*	*				168.1	140.9	76.3	0	0	0	0	0	112.8
9	N	27.6	Very low	30.4	Very low	150 Å²	150	141.6 Å²	141.6	80%	0.802	81%	0.812	S	S	*	*			trans	-45.4	159.6	174.5	-63.1	-30.2	0	0	0	113.4
10	T	26.7	Very low	31	Very low	126 Å²	126	141.1 Å²	141.1	77%	0.773	81%	0.811	S	S	*	*			cis	178.7	138.4	47.4	-23.5	0	0	0	0	103.3
11	V	29.3	Very low	31.3	Very low	123 Å²	123	142 Å²	142	75%	0.745	81%	0.808	S	S	*	*				-176	117.9	75.1	171.2	0	0	0	0	105.3
12	G	27.7	Very low	31.9	Very low	75 Å²	75	137.9 Å²	137.9	77%	0.773	79%	0.791	S	S	*	*			trans	-134.9	112.6	171.7	0	0	0	0	0	108.4	S14	G12-S14 PolarHBondContact O-N 3.09Å
13	Y	31.3	Very low	32.6	Very low	219 Å²	219	135.8 Å²	135.8	86%	0.859	78%	0.777	S	S	*	*			trans	-54.9	128.8	178.4	-85.2	-97.3	0	0	0	110.8	L15	Y13-L15 PolarHBondContact O-N 3.38Å; Y13-L15 VanDerWaalsContact O-N 3.17Å
14	S	29.2	Very low	33.9	Very low	113 Å²	113	141.3 Å²	141.3	79%	0.79	78%	0.784	S	S	*	*			trans	-68.6	104.1	176.4	-177.1	0	0	0	0	110.1	G12 K16	G12-S14 PolarHBondContact O-N 3.09Å; S14-K16 PolarHBondContact O-N 3.37Å
15	L	32.2	Very low	34.9	Very low	170 Å²	170	143.7 Å²	143.7	89%	0.89	78%	0.783	S	S	*	*			trans	-68.3	106.9	160.6	-92.7	151.6	0	0	0	107.5	Y13 K17	Y13-L15 PolarHBondContact O-N 3.38Å; Y13-L15 VanDerWaalsContact O-N 3.17Å; L15-K17 PolarHBondContact O-N 3.14Å
16	K	35.8	Very low	35.7	Very low	185 Å²	185	145.1 Å²	145.1	80%	0.804	79%	0.785	S	S	*	*			trans	-50.8	124.1	165	-86.8	178	172.5	178.6	0	108.4	S14 L18	S14-K16 PolarHBondContact O-N 3.37Å; K16-L18 PolarHBondContact O-N 2.92Å
17	K	37.1	Very low	37.1	Very low	210 Å²	210	140.9 Å²	140.9	91%	0.913	77%	0.771	S	S	*	*			trans	-52.1	102.9	159.5	-101.7	177.7	169.5	-179.1	0	107.7	L15 S19	L15-K17 PolarHBondContact O-N 3.14Å; K17-S19 PolarHBondContact O-N 2.69Å
18	L	30.6	Very low	38.6	Very low	158 Å²	158	139.3 Å²	139.3	83%	0.827	76%	0.763	S	S	*	*			trans	-72.8	113	150.4	-95.2	100.4	0	0	0	105.7	K16 V20	K16-L18 PolarHBondContact O-N 2.92Å; L18-V20 PolarHBondContact O-N 2.75Å
19	S	34.6	Very low	40.5	Very low	91 Å²	91	140.6 Å²	140.6	64%	0.636	77%	0.767	S	S	*	*			trans	-56.7	117.1	157.5	42.1	0	0	0	0	107.1	K17 E21	K17-S19 PolarHBondContact O-N 2.69Å; S19-E21 PolarHBondContact O-N 2.74Å
20	V	41.2	Very low	42.5	Very low	131 Å²	131	140.6 Å²	140.6	79%	0.794	76%	0.762	S	S	*	*			trans	-68.4	92.4	159.1	-179	0	0	0	0	104.2	L18 D22	L18-V20 PolarHBondContact O-N 2.75Å; V20-D22 PolarHBondContact O-N 2.95Å
21	E	38.1	Very low	44.6	Very low	160 Å²	160	139.2 Å²	139.2	75%	0.748	75%	0.753	S	S	*	*			trans	-59.9	122.3	154.7	-73.7	176.5	164.8	0	0	104.9	S19 S23	S19-E21 PolarHBondContact O-N 2.74Å; E21-S23 PolarHBondContact O-N 3.42Å
22	D	44.5	Very low	46.3	Very low	155 Å²	155	136.5 Å²	136.5	83%	0.829	75%	0.751	S	S	*	*			trans	-60.1	83.3	162.4	-83.9	-34.4	0	0	0	106.3	V20 E24	V20-D22 PolarHBondContact O-N 2.95Å; D22-E24 VanDerWaalsContact C-N 3.33Å; D22-E24 PolarHBondContact O-N 3.24Å; D22-E24 VanDerWaalsContact O-N 3.09Å
23	S	43.8	Very low	48.2	Very low	85 Å²	85	137.7 Å²	137.7	59%	0.594	74%	0.743	S	S	*	*			trans	-64.8	107.1	155.5	55.5	0	0	0	0	104.3	E21 E25	E21-S23 PolarHBondContact O-N 3.42Å; S23-E25 PolarHBondContact O-N 2.95Å
24	E	52.6	Low	49.8	Very low	184 Å²	184	132.4 Å²	132.4	86%	0.86	73%	0.729	S	S	*	*			trans	-53.1	83.3	152.4	-68.5	-177.7	163.6	0	0	106.1	D22 D26	D22-E24 VanDerWaalsContact C-N 3.33Å; D22-E24 PolarHBondContact O-N 3.24Å; D22-E24 VanDerWaalsContact O-N 3.09Å; E24-D26 VanDerWaalsContact C-N 3.25Å; E24-D26 PolarHBondContact O-N 3.27Å
25	E	51.5	Low	51.7	Low	166 Å²	166	137 Å²	137	78%	0.776	73%	0.73	S	S	*	*			trans	-61.1	102.4	162.1	-79.7	-173.1	164.6	0	0	103.8	S23 N27	S23-E25 PolarHBondContact O-N 2.95Å; E25-N27 VanDerWaalsContact C-N 3.27Å; E25-N27 PolarHBondContact O-N 3.21Å
26	D	55.4	Low	53.1	Low	141 Å²	141	133.1 Å²	133.1	75%	0.754	72%	0.722	S	S	*	*			trans	-46.4	99.3	167.9	-101.6	-33	0	0	0	107	E24 D28	E24-D26 VanDerWaalsContact C-N 3.25Å; E24-D26 PolarHBondContact O-N 3.27Å; D26-D28 PolarHBondContact O-N 2.96Å
27	N	55.3	Low	54.3	Low	90 Å²	90	128.8 Å²	128.8	48%	0.481	71%	0.714	S	S	.	*			trans	-81.4	73.5	-174.1	-152.8	-17	0	0	0	106.2	E25 A29 Q30	E25-N27 VanDerWaalsContact C-N 3.27Å; E25-N27 PolarHBondContact O-N 3.21Å; N27-A29 PolarHBondContact O-N 2.95Å; N27-Q30 HydrophobicContact CB-CG 4.48Å; N27-Q30 PolarHBondContact ND2-NE2 3.41Å; N27-Q30 PolarHBondContact O-N 2.97Å
28	D	61.8	Low	55.5	Low	125 Å²	125	126.6 Å²	126.6	67%	0.668	71%	0.705	S	S	*	*	G	3₁₀ helix	trans	-51.3	-23.8	-178.8	-96	-15.9	0	0	0	112.2	D26 Q30 T31	D26-D28 PolarHBondContact O-N 2.96Å; D28-Q30 PolarHBondContact O-N 3.49Å; D28-T31 PolarHBondContact O-OG1 3.28Å
29	A	65.1	Low	57.1	Low	95 Å²	95	122.2 Å²	122.2	79%	0.785	70%	0.698	S	S	*	*	G	3₁₀ helix	trans	-64.5	-20.2	173.2	0	0	0	0	0	114.1	N27	N27-A29 PolarHBondContact O-N 2.95Å
30	Q	69.6	Low	59	Low	151 Å²	151	120.9 Å²	120.9	71%	0.706	70%	0.699	S	S	*	*	G	3₁₀ helix	trans	-110.3	-3.8	-175.7	-59.1	-172.1	5.7	0	0	113.8	N27 D28 G32	N27-Q30 HydrophobicContact CB-CG 4.48Å; N27-Q30 PolarHBondContact ND2-NE2 3.41Å; N27-Q30 PolarHBondContact O-N 2.97Å; D28-Q30 PolarHBondContact O-N 3.49Å; Q30-G32 PolarHBondContact O-N 3.13Å; Q30-G32 VanDerWaalsContact O-N 3.13Å
31	T	70.4	Confident	60.8	Low	96 Å²	96	121.2 Å²	121.2	59%	0.589	70%	0.695	S	S	*	*			trans	-76.6	6.4	-178.3	58.8	0	0	0	0	113.8	D28	D28-T31 PolarHBondContact O-OG1 3.28Å
32	G	63.8	Low	63.2	Low	67 Å²	67	118.4 Å²	118.4	69%	0.691	68%	0.684	S	S	*	*			trans	-76.2	134.6	-178.9	0	0	0	0	0	114.3	Q30	Q30-G32 PolarHBondContact O-N 3.13Å; Q30-G32 VanDerWaalsContact O-N 3.13Å
33	V	68.4	Low	65.3	Low	100 Å²	100	119 Å²	119	61%	0.606	68%	0.676	S	S	*	*			trans	-80.1	121.7	171.7	-178.7	0	0	0	0	109.7	R35	V33-R35 PolarHBondContact O-N 2.81Å
34	N	65.4	Low	67.6	Low	107 Å²	107	115.9 Å²	115.9	57%	0.572	66%	0.658	S	S	*	*			trans	-64.2	102.2	172.2	-174.8	-16.3	0	0	0	110.1	A36 S37	N34-A36 WeakPolarHBondContact OD1-CB 3.33Å; N34-A36 PolarHBondContact OD1-N 2.95Å; N34-S37 PolarHBondContact O-OG 3.23Å; N34-S37 PolarHBondContact OD1-N 3.44Å
35	R	67.9	Low	69.5	Low	211 Å²	211	112 Å²	112	80%	0.796	64%	0.643	S	S	*	*			trans	-83.8	-14.2	178.2	-64.2	-173.1	-178	-171.5	0.6	113.1	V33 S37 K38	V33-R35 PolarHBondContact O-N 2.81Å; R35-S37 VanDerWaalsContact C-N 3.28Å; R35-S37 PolarHBondContact O-N 2.79Å; R35-K38 PolarHBondContact O-N 3.17Å
36	A	62.3	Low	71.5	Confident	88 Å²	88	111.7 Å²	111.7	73%	0.727	64%	0.636	S	S	*	*	G	3₁₀ helix	trans	-69	-26.7	-180	0	0	0	0	0	112.5	N34	N34-A36 WeakPolarHBondContact OD1-CB 3.33Å; N34-A36 PolarHBondContact OD1-N 2.95Å
37	S	62	Low	73.4	Confident	93 Å²	93	107.8 Å²	107.8	65%	0.65	62%	0.615	S	S	*	*	G	3₁₀ helix	trans	-81.4	-9	178.7	57.8	0	0	0	0	114.7	N34 R35	N34-S37 PolarHBondContact O-OG 3.23Å; N34-S37 PolarHBondContact OD1-N 3.44Å; R35-S37 VanDerWaalsContact C-N 3.28Å; R35-S37 PolarHBondContact O-N 2.79Å
38	K	60.5	Low	75.4	Confident	164 Å²	164	107.9 Å²	107.9	71%	0.713	61%	0.612	S	S	*	*	G	3₁₀ helix	trans	-92.9	6.8	-176.6	-69.2	-170.4	176.5	-175.5	0	114.5	R35	R35-K38 PolarHBondContact O-N 3.17Å
39	G	64.5	Low	77	Confident	66 Å²	66	104 Å²	104	68%	0.68	59%	0.591	S	S	*	*	S	Bend	trans	82	136.8	-173.9	0	0	0	0	0	112.3
40	G	73.9	Confident	78.5	Confident	63 Å²	63	104 Å²	104	65%	0.649	58%	0.575	S	S	*	*	S	Bend	trans	153.8	-173.7	-173.2	0	0	0	0	0	112	I42	G40-I42 PolarHBondContact O-N 3.36Å
41	L	79.8	Confident	79.8	Confident	139 Å²	139	102.7 Å²	102.7	73%	0.728	57%	0.567	S	S	*	*			trans	-62.7	121.3	176.1	-175.9	66.8	0	0	0	110.4	Y46	L41-Y46 HydrophobicContact CD2-CD2 3.72Å; L41-Y46 HydrophobicContact CD2-CG 4.03Å
42	I	88.1	Confident	81.1	Confident	101 Å²	101	101.7 Å²	101.7	52%	0.518	56%	0.557	S	S	.	*			trans	-92.5	139.2	-179.8	-58.6	173.6	0	0	0	109.1	G40 G44 N45 Y46	G40-I42 PolarHBondContact O-N 3.36Å; I42-G44 VanDerWaalsContact C-N 3.32Å; I42-G44 PolarHBondContact O-N 2.93Å; I42-N45 HydrophobicContact CB-CB 4.46Å; I42-N45 PolarHBondContact O-N 3.02Å; I42-Y46 PolarHBondContact O-N 3.25Å
43	Y	89.8	Confident	82.8	Confident	166 Å²	166	103.6 Å²	103.6	65%	0.651	55%	0.551	S	S	*	*	H	α-helix	trans	-48.2	-49.8	-179.3	178.4	-98.2	0	0	0	113.4	N45 Y46 L47 L49	Y43-N45 VanDerWaalsContact C-N 3.31Å; Y43-N45 PolarHBondContact O-N 3.27Å; Y43-Y46 PolarHBondContact O-N 3.37Å; Y43-L47 HydrophobicContact CD1-CD1 4.33Å; Y43-L47 HydrophobicContact CD2-CD1 4.12Å; Y43-L47 HydrophobicContact CE1-CD1 3.68Å; Y43-L47 HydrophobicContact CE2-CD1 3.43Å; Y43-L47 VanDerWaalsContact CE2-CD1 3.43Å; Y43-L47 HydrophobicContact CE2-CG 4.29Å; Y43-L47 PolarHBondContact O-N 2.78Å; Y43-L47 VanDerWaalsContact OH-CD1 3.24Å; Y43-L47 WeakPolarHBondContact OH-CD1 3.48Å; Y43-L49 HydrophobicContact CD1-CD1 4Å; Y43-L49 HydrophobicContact CE1-CD1 3.79Å
44	G	91.7	Very high	84.2	Confident	20 Å²	20	105 Å²	105	21%	0.206	56%	0.555	C	S	.	*	H	α-helix	trans	-58.8	-41.6	179.1	0	0	0	0	0	113	I42 Q48 L49	I42-G44 VanDerWaalsContact C-N 3.32Å; I42-G44 PolarHBondContact O-N 2.93Å; G44-Q48 WeakPolarHBondContact O-CA 3.27Å; G44-Q48 PolarHBondContact O-N 3.06Å; G44-L49 PolarHBondContact O-N 3.07Å
45	N	91.6	Very high	85.8	Confident	104 Å²	104	102.4 Å²	102.4	56%	0.556	55%	0.548	S	S	*	.	H	α-helix	trans	-72.1	-38.3	179.5	-62.3	-1.2	0	0	0	111.7	I42 Y43 Q48	I42-N45 HydrophobicContact CB-CB 4.46Å; I42-N45 PolarHBondContact O-N 3.02Å; Y43-N45 VanDerWaalsContact C-N 3.31Å; Y43-N45 PolarHBondContact O-N 3.27Å; N45-Q48 PolarHBondContact O-N 3.36Å
46	Y	93.8	Very high	87.2	Confident	159 Å²	159	94.4 Å²	94.4	62%	0.624	52%	0.52	S	S	*	.	H	α-helix	trans	-63.5	-45.1	178.1	173.8	-114.4	0	0	0	112	L41 I42 Y43 Q48	L41-Y46 HydrophobicContact CD2-CD2 3.72Å; L41-Y46 HydrophobicContact CD2-CG 4.03Å; I42-Y46 PolarHBondContact O-N 3.25Å; Y43-Y46 PolarHBondContact O-N 3.37Å; Y46-Q48 VanDerWaalsContact C-N 3.28Å; Y46-Q48 PolarHBondContact O-N 2.96Å
47	L	95.5	Very high	88.9	Confident	59 Å²	59	96.4 Å²	96.4	31%	0.309	51%	0.514	S	S	.	.	T	Hydrogen-bonded Turn	trans	-84.6	-1.5	179.6	-62.9	-174.8	0	0	0	113.7	Y43 L49 I52	Y43-L47 HydrophobicContact CD1-CD1 4.33Å; Y43-L47 HydrophobicContact CD2-CD1 4.12Å; Y43-L47 HydrophobicContact CE1-CD1 3.68Å; Y43-L47 HydrophobicContact CE2-CD1 3.43Å; Y43-L47 VanDerWaalsContact CE2-CD1 3.43Å; Y43-L47 HydrophobicContact CE2-CG 4.29Å; Y43-L47 PolarHBondContact O-N 2.78Å; Y43-L47 VanDerWaalsContact OH-CD1 3.24Å; Y43-L47 WeakPolarHBondContact OH-CD1 3.48Å; L47-L49 VanDerWaalsContact C-N 3.26Å; L47-L49 HydrophobicContact CB-CD2 3.74Å; L47-L49 HydrophobicContact CB-CG 3.97Å; L47-L49 HydrophobicContact CD1-CD2 4.26Å; L47-L49 PolarHBondContact O-N 3.5Å; L47-I52 VanDerWaalsContact O-CD1 3.27Å; L47-I52 WeakPolarHBondContact O-CD1 3.16Å
48	Q	96.9	Very high	90.7	Very high	91 Å²	91	92.3 Å²	92.3	43%	0.425	49%	0.485	S	S	.	.	T	Hydrogen-bonded Turn	trans	50.8	46.4	-174.8	-58.5	-174.7	3	0	0	112	G44 N45 Y46 E50 K51 I52	G44-Q48 WeakPolarHBondContact O-CA 3.27Å; G44-Q48 PolarHBondContact O-N 3.06Å; N45-Q48 PolarHBondContact O-N 3.36Å; Y46-Q48 VanDerWaalsContact C-N 3.28Å; Y46-Q48 PolarHBondContact O-N 2.96Å; Q48-E50 WeakPolarHBondContact CA-OE2 3.28Å; Q48-E50 PolarHBondContact O-N 3.33Å; Q48-E50 VanDerWaalsContact O-N 3.15Å; Q48-K51 HydrophobicContact CB-CD 4.34Å; Q48-K51 PolarHBondContact O-N 3.32Å; Q48-I52 PolarHBondContact O-N 2.91Å; Q48-I52 VanDerWaalsContact O-N 3.16Å
49	L	96.6	Very high	92.4	Very high	45 Å²	45	88 Å²	88	24%	0.236	47%	0.467	C	S	.	.	H	α-helix	trans	-62.2	-22.8	-176.9	-64.5	-173.2	0	0	0	112.2	Y43 G44 L47 K51 I52 L53	Y43-L49 HydrophobicContact CD1-CD1 4Å; Y43-L49 HydrophobicContact CE1-CD1 3.79Å; G44-L49 PolarHBondContact O-N 3.07Å; L47-L49 VanDerWaalsContact C-N 3.26Å; L47-L49 HydrophobicContact CB-CD2 3.74Å; L47-L49 HydrophobicContact CB-CG 3.97Å; L47-L49 HydrophobicContact CD1-CD2 4.26Å; L47-L49 PolarHBondContact O-N 3.5Å; L49-K51 PolarHBondContact O-N 3.16Å; L49-I52 PolarHBondContact O-N 3.15Å; L49-L53 HydrophobicContact CB-CD1 4Å; L49-L53 HydrophobicContact CB-CG 4.21Å; L49-L53 HydrophobicContact CD1-CD1 4.23Å; L49-L53 HydrophobicContact CD2-CD1 4.44Å; L49-L53 HydrophobicContact CD2-CG 4.44Å; L49-L53 HydrophobicContact CG-CD1 4.45Å; L49-L53 VanDerWaalsContact O-CB 3.28Å; L49-L53 WeakPolarHBondContact O-CB 3.24Å; L49-L53 PolarHBondContact O-N 3.42Å
50	E	96.7	Very high	94	Very high	93 Å²	93	84.8 Å²	84.8	44%	0.435	44%	0.435	S	S	.	.	H	α-helix	trans	-62.5	-26.3	171.9	78	-67.9	164.4	0	0	112.9	Q48 N54	Q48-E50 WeakPolarHBondContact CA-OE2 3.28Å; Q48-E50 PolarHBondContact O-N 3.33Å; Q48-E50 VanDerWaalsContact O-N 3.15Å; E50-N54 WeakPolarHBondContact O-CB 3.38Å; E50-N54 PolarHBondContact O-ND2 2.79Å
51	K	97.1	Very high	95.2	Very high	125 Å²	125	86.2 Å²	86.2	54%	0.543	42%	0.424	S	S	.	.	H	α-helix	trans	-88.9	-47	172.9	-61.8	179.9	-170.2	169.8	0	110.9	Q48 L49	Q48-K51 HydrophobicContact CB-CD 4.34Å; Q48-K51 PolarHBondContact O-N 3.32Å; L49-K51 PolarHBondContact O-N 3.16Å
52	I	97.4	Very high	96	Very high	74 Å²	74	83.7 Å²	83.7	38%	0.379	41%	0.411	S	S	.	.	H	α-helix	trans	-66.4	-45.6	-174	-61.2	179.1	0	0	0	111.3	L47 Q48 L49 N54 Q56	L47-I52 VanDerWaalsContact O-CD1 3.27Å; L47-I52 WeakPolarHBondContact O-CD1 3.16Å; Q48-I52 PolarHBondContact O-N 2.91Å; Q48-I52 VanDerWaalsContact O-N 3.16Å; L49-I52 PolarHBondContact O-N 3.15Å; I52-N54 VanDerWaalsContact C-N 3.33Å; I52-Q56 PolarHBondContact O-NE2 2.85Å
53	L	98.3	Very high	96.4	Very high	108 Å²	108	85.7 Å²	85.7	57%	0.565	42%	0.416	S	S	*	.	T	Hydrogen-bonded Turn	trans	-89.8	6.1	-174.7	-54.8	-178.4	0	0	0	113.9	L49 Q56	L49-L53 HydrophobicContact CB-CD1 4Å; L49-L53 HydrophobicContact CB-CG 4.21Å; L49-L53 HydrophobicContact CD1-CD1 4.23Å; L49-L53 HydrophobicContact CD2-CD1 4.44Å; L49-L53 HydrophobicContact CD2-CG 4.44Å; L49-L53 HydrophobicContact CG-CD1 4.45Å; L49-L53 VanDerWaalsContact O-CB 3.28Å; L49-L53 WeakPolarHBondContact O-CB 3.24Å; L49-L53 PolarHBondContact O-N 3.42Å; L53-Q56 PolarHBondContact O-OE1 3.01Å
54	N	98.3	Very high	96.7	Very high	130 Å²	130	81.2 Å²	81.2	70%	0.695	42%	0.42	S	S	*	.	T	Hydrogen-bonded Turn	trans	-122.2	23.6	172.3	-64.3	-60.7	0	0	0	111.9	E50 I52	E50-N54 WeakPolarHBondContact O-CB 3.38Å; E50-N54 PolarHBondContact O-ND2 2.79Å; I52-N54 VanDerWaalsContact C-N 3.33Å
55	A	98.3	Very high	97	Very high	51 Å²	51	84 Å²	84	42%	0.421	43%	0.43	S	S	.	.			trans	-103.3	11.8	179	0	0	0	0	0	112.9	Q78	A55-Q78 PolarHBondContact O-NE2 2.81Å
56	Q	98.4	Very high	97.3	Very high	43 Å²	43	85 Å²	85	20%	0.201	43%	0.429	C	S	.	.			trans	-101	82.1	-172.9	-64.7	70.3	42.3	0	0	111.3	I52 L53 I75	I52-Q56 PolarHBondContact O-NE2 2.85Å; L53-Q56 PolarHBondContact O-OE1 3.01Å; Q56-I75 HydrophobicContact CG-CD1 3.53Å; Q56-I75 HydrophobicContact CG-CG1 4.29Å
57	E	98.2	Very high	97.5	Very high	130 Å²	130	78.7 Å²	78.7	61%	0.607	41%	0.406	S	S	*	.			trans	-105.6	113.7	-179.7	-166	-175.4	-157.1	0	0	111.4	I62 I74	E57-I62 HydrophobicContact CG-CD1 3.77Å; E57-I62 HydrophobicContact CG-CG1 4.3Å; E57-I62 VanDerWaalsContact OE1-CD1 3.26Å; E57-I62 WeakPolarHBondContact OE1-CD1 3.26Å; E57-I74 VanDerWaalsContact O-CD1 3.31Å; E57-I74 WeakPolarHBondContact O-CD1 3.38Å
58	L	98.4	Very high	97.6	Very high	8 Å²	8	83.4 Å²	83.4	4%	0.042	43%	0.426	C	S	.	.			trans	-83.7	120.1	-179.5	-81.1	69.8	0	0	0	110.2	S60 E61 I62 K66 E70 H71 I74	L58-S60 VanDerWaalsContact C-N 3.28Å; L58-S60 PolarHBondContact O-N 2.98Å; L58-E61 HydrophobicContact CB-CB 3.76Å; L58-E61 PolarHBondContact O-N 3.35Å; L58-I62 WeakPolarHBondContact O-CG1 3.47Å; L58-I62 PolarHBondContact O-N 3.36Å; L58-I62 VanDerWaalsContact O-N 3.13Å; L58-K66 HydrophobicContact CD2-CG 4.33Å; L58-E70 HydrophobicContact CB-CG 4.49Å; L58-E70 WeakPolarHBondContact CB-OE2 3.42Å; L58-E70 HydrophobicContact CD2-CB 4.11Å; L58-E70 HydrophobicContact CG-CB 4.1Å; L58-E70 HydrophobicContact CG-CG 4.08Å; L58-H71 HydrophobicContact CD1-CB 4.17Å; L58-H71 HydrophobicContact CD2-CB 4.35Å; L58-I74 HydrophobicContact CD1-CD1 3.92Å; L58-I74 HydrophobicContact CG-CD1 4.08Å
59	Q	98.1	Very high	97.7	Very high	72 Å²	72	80.5 Å²	80.5	34%	0.336	41%	0.414	S	S	.	.	H	α-helix	trans	-65.5	-35.2	176.9	-66.7	-61.3	-56	0	0	111.4	E61 I62 K63 E70	Q59-E61 VanDerWaalsContact C-N 3.3Å; Q59-E61 PolarHBondContact O-N 3.37Å; Q59-I62 PolarHBondContact O-N 3.24Å; Q59-K63 VanDerWaalsContact O-CG 3.28Å; Q59-K63 WeakPolarHBondContact O-CG 3.42Å; Q59-K63 PolarHBondContact O-N 3.3Å; Q59-E70 WeakPolarHBondContact CB-OE1 3.47Å; Q59-E70 PolarHBondContact N-OE1 3.28Å; Q59-E70 PolarHBondContact N-OE2 3.13Å
60	S	97.5	Very high	97.8	Very high	0 Å²	0	78.5 Å²	78.5	0%	0	40%	0.403	C	S	.	.	H	α-helix	trans	-61.8	-39.2	175.9	72.9	0	0	0	0	112	L58 K63 G64 N65 I67 E70 Y147	L58-S60 VanDerWaalsContact C-N 3.28Å; L58-S60 PolarHBondContact O-N 2.98Å; S60-K63 CarbonylContact O-C 3.2Å; S60-K63 PolarHBondContact O-N 3.42Å; S60-G64 PolarHBondContact O-N 2.82Å; S60-N65 CarbonylContact C-O 3.58Å; S60-N65 WeakPolarHBondContact CB-O 3.29Å; S60-N65 CarbonylContact O-C 3.53Å; S60-N65 PolarHBondContact O-N 3.23Å; S60-N65 PolarHBondContact OG-O 2.74Å; S60-I67 PolarHBondContact OG-N 3.25Å; S60-E70 WeakPolarHBondContact CB-OE2 3.25Å; S60-E70 PolarHBondContact N-OE2 2.83Å; S60-E70 PolarHBondContact OG-OE2 3.4Å; S60-Y147 VanDerWaalsContact CB-CD2 3.44Å; S60-Y147 VanDerWaalsContact CB-CE2 3.41Å
61	E	97.8	Very high	97.9	Very high	92 Å²	92	78.3 Å²	78.3	43%	0.43	40%	0.402	S	S	.	.	H	α-helix	trans	-67.6	-43.5	176.8	-174	161.4	-157.3	0	0	111.8	L58 Q59 K63 G64 K66	L58-E61 HydrophobicContact CB-CB 3.76Å; L58-E61 PolarHBondContact O-N 3.35Å; Q59-E61 VanDerWaalsContact C-N 3.3Å; Q59-E61 PolarHBondContact O-N 3.37Å; E61-K63 PolarHBondContact O-N 2.56Å; E61-G64 PolarHBondContact O-N 3.4Å; E61-K66 HydrophobicContact CB-CB 4.08Å; E61-K66 HydrophobicContact CB-CG 4.11Å; E61-K66 HydrophobicContact CG-CB 4.25Å; E61-K66 HydrophobicContact CG-CD 4.23Å; E61-K66 HydrophobicContact CG-CG 4.3Å; E61-K66 IonicContact OE1-NZ 2.82Å; E61-K66 PolarHBondContact OE1-NZ 2.85Å; E61-K66 VanDerWaalsContact OE2-CE 3.29Å; E61-K66 WeakPolarHBondContact OE2-CE 3.31Å; E61-K66 IonicContact OE2-NZ 2.83Å; E61-K66 PolarHBondContact OE2-NZ 3.15Å
62	I	97.1	Very high	97.9	Very high	86 Å²	86	74.2 Å²	74.2	44%	0.441	39%	0.386	S	S	.	.	H	α-helix	trans	-58.3	-38.1	174	-62.6	171.1	0	0	0	111.3	E57 L58 Q59 G64	E57-I62 HydrophobicContact CG-CD1 3.77Å; E57-I62 HydrophobicContact CG-CG1 4.3Å; E57-I62 VanDerWaalsContact OE1-CD1 3.26Å; E57-I62 WeakPolarHBondContact OE1-CD1 3.26Å; L58-I62 WeakPolarHBondContact O-CG1 3.47Å; L58-I62 PolarHBondContact O-N 3.36Å; L58-I62 VanDerWaalsContact O-N 3.13Å; Q59-I62 PolarHBondContact O-N 3.24Å; I62-G64 PolarHBondContact O-N 2.7Å
63	K	96.4	Very high	98	Very high	143 Å²	143	72.7 Å²	72.7	62%	0.622	38%	0.377	S	S	*	.	T	Hydrogen-bonded Turn	trans	-80.6	3.3	178.7	-60.9	-59.3	-179.3	-173.1	0	113.5	Q59 S60 E61 Y147	Q59-K63 VanDerWaalsContact O-CG 3.28Å; Q59-K63 WeakPolarHBondContact O-CG 3.42Å; Q59-K63 PolarHBondContact O-N 3.3Å; S60-K63 CarbonylContact O-C 3.2Å; S60-K63 PolarHBondContact O-N 3.42Å; E61-K63 PolarHBondContact O-N 2.56Å; K63-Y147 HydrophobicContact CB-CD1 4.2Å; K63-Y147 HydrophobicContact CB-CE1 3.92Å; K63-Y147 HydrophobicContact CG-CD1 3.85Å; K63-Y147 HydrophobicContact CG-CE1 4.06Å
64	G	96.9	Very high	98	Very high	72 Å²	72	68.9 Å²	68.9	74%	0.742	36%	0.357	S	S	*	.	T	Hydrogen-bonded Turn	trans	82.8	12.3	175.6	0	0	0	0	0	114.8	S60 E61 I62	S60-G64 PolarHBondContact O-N 2.82Å; E61-G64 PolarHBondContact O-N 3.4Å; I62-G64 PolarHBondContact O-N 2.7Å
65	N	96.9	Very high	98	Very high	79 Å²	79	65.9 Å²	65.9	42%	0.422	34%	0.34	S	S	.	.			trans	-132.1	69.5	179.8	-177.2	35.5	0	0	0	110.5	S60 I67 Y147	S60-N65 CarbonylContact C-O 3.58Å; S60-N65 WeakPolarHBondContact CB-O 3.29Å; S60-N65 CarbonylContact O-C 3.53Å; S60-N65 PolarHBondContact O-N 3.23Å; S60-N65 PolarHBondContact OG-O 2.74Å; N65-I67 PolarHBondContact O-N 3.13Å; N65-Y147 PolarHBondContact ND2-OH 2.91Å; N65-Y147 VanDerWaalsContact ND2-OH 3.12Å
66	K	97.8	Very high	98	Very high	124 Å²	124	63.8 Å²	63.8	54%	0.539	32%	0.322	S	S	.	.			trans	-60.3	119.6	-175.1	-177.8	178.2	-169.2	141.4	0	112.2	L58 E61	L58-K66 HydrophobicContact CD2-CG 4.33Å; E61-K66 HydrophobicContact CB-CB 4.08Å; E61-K66 HydrophobicContact CB-CG 4.11Å; E61-K66 HydrophobicContact CG-CB 4.25Å; E61-K66 HydrophobicContact CG-CD 4.23Å; E61-K66 HydrophobicContact CG-CG 4.3Å; E61-K66 IonicContact OE1-NZ 2.82Å; E61-K66 PolarHBondContact OE1-NZ 2.85Å; E61-K66 VanDerWaalsContact OE2-CE 3.29Å; E61-K66 WeakPolarHBondContact OE2-CE 3.31Å; E61-K66 IonicContact OE2-NZ 2.83Å; E61-K66 PolarHBondContact OE2-NZ 3.15Å
67	I	98.3	Very high	98	Very high	27 Å²	27	65.5 Å²	65.5	14%	0.138	33%	0.33	C	S	.	.			trans	-105.3	127.8	173.5	-52.5	-55.7	0	0	0	110	S60 N65 E70 D143 F144	S60-I67 PolarHBondContact OG-N 3.25Å; N65-I67 PolarHBondContact O-N 3.13Å; I67-E70 PolarHBondContact O-N 2.97Å; I67-D143 HydrophobicContact CD1-CB 4.14Å; I67-D143 HydrophobicContact CG1-CB 4.37Å; I67-D143 HydrophobicContact CG2-CB 4.36Å; I67-F144 HydrophobicContact CB-CB 3.94Å; I67-F144 HydrophobicContact CB-CD1 4.4Å; I67-F144 HydrophobicContact CG1-CB 3.94Å; I67-F144 HydrophobicContact CG2-CB 4.17Å; I67-F144 HydrophobicContact CG2-CD1 3.79Å; I67-F144 HydrophobicContact CG2-CG 4.42Å
68	H	98.4	Very high	98	Very high	158 Å²	158	62 Å²	62	73%	0.731	31%	0.313	S	S	*	.	T	Hydrogen-bonded Turn	trans	-61.3	-49.2	-172.3	-178.4	72.8	0	0	0	113.2	E70 H71	H68-E70 PolarHBondContact O-N 3.44Å; H68-H71 PolarHBondContact O-N 2.91Å
69	D	98.4	Very high	98	Very high	30 Å²	30	63 Å²	63	16%	0.16	32%	0.323	C	S	.	.	H	α-helix	trans	-70.2	-11.9	-173.8	-81.8	20.5	0	0	0	113.7	H71 L72 F73 M136 D140 F144	D69-H71 PolarHBondContact O-N 3.4Å; D69-L72 WeakPolarHBondContact O-CB 3.29Å; D69-L72 PolarHBondContact O-N 2.92Å; D69-F73 PolarHBondContact O-N 3.17Å; D69-M136 HydrophobicContact CB-CG 4.04Å; D69-M136 HydrophobicContact CB-SD 3.88Å; D69-M136 VanDerWaalsContact OD2-CG 3.3Å; D69-M136 WeakPolarHBondContact OD2-CG 3.22Å; D69-D140 HydrophobicContact CB-CB 4.44Å; D69-F144 HydrophobicContact CB-CE1 4.21Å
70	E	98.5	Very high	98	Very high	3 Å²	3	60.1 Å²	60.1	1%	0.014	31%	0.309	C	S	.	.	H	α-helix	trans	-61.8	-33.8	171.7	-170.7	-177.4	-171.6	0	0	111.3	L58 Q59 S60 I67 H68 L72 F73 I74 F144	L58-E70 HydrophobicContact CB-CG 4.49Å; L58-E70 WeakPolarHBondContact CB-OE2 3.42Å; L58-E70 HydrophobicContact CD2-CB 4.11Å; L58-E70 HydrophobicContact CG-CB 4.1Å; L58-E70 HydrophobicContact CG-CG 4.08Å; Q59-E70 WeakPolarHBondContact CB-OE1 3.47Å; Q59-E70 PolarHBondContact N-OE1 3.28Å; Q59-E70 PolarHBondContact N-OE2 3.13Å; S60-E70 WeakPolarHBondContact CB-OE2 3.25Å; S60-E70 PolarHBondContact N-OE2 2.83Å; S60-E70 PolarHBondContact OG-OE2 3.4Å; I67-E70 PolarHBondContact O-N 2.97Å; H68-E70 PolarHBondContact O-N 3.44Å; E70-L72 PolarHBondContact O-N 3.3Å; E70-F73 WeakPolarHBondContact O-CB 3.42Å; E70-F73 PolarHBondContact O-N 3.43Å; E70-I74 HydrophobicContact CG-CD1 4.1Å; E70-I74 WeakPolarHBondContact O-CG1 3.42Å; E70-I74 PolarHBondContact O-N 3.49Å; E70-F144 HydrophobicContact CB-CB 4.39Å; E70-F144 HydrophobicContact CB-CD1 4.33Å; E70-F144 HydrophobicContact CB-CD2 4Å; E70-F144 HydrophobicContact CB-CE2 4.29Å; E70-F144 HydrophobicContact CB-CG 4.01Å; E70-F144 HydrophobicContact CG-CD2 3.88Å; E70-F144 HydrophobicContact CG-CE2 4.21Å; E70-F144 HydrophobicContact CG-CG 4.33Å
71	H	98.7	Very high	98.1	Very high	89 Å²	89	63 Å²	63	41%	0.412	32%	0.322	S	S	.	.	H	α-helix	trans	-63.8	-42.4	175.5	-171.5	-77.5	0	0	0	111.7	L58 H68 D69 F73 I74 I75	L58-H71 HydrophobicContact CD1-CB 4.17Å; L58-H71 HydrophobicContact CD2-CB 4.35Å; H68-H71 PolarHBondContact O-N 2.91Å; D69-H71 PolarHBondContact O-N 3.4Å; H71-F73 VanDerWaalsContact C-N 3.33Å; H71-I74 PolarHBondContact O-N 3.48Å; H71-I75 VanDerWaalsContact CE1-CG1 3.47Å; H71-I75 WeakPolarHBondContact CE1-CG1 3.34Å; H71-I75 WeakPolarHBondContact O-CG1 3.38Å; H71-I75 PolarHBondContact O-N 3.16Å
72	L	98.6	Very high	98.1	Very high	40 Å²	40	63.4 Å²	63.4	21%	0.209	33%	0.327	C	S	.	.	H	α-helix	trans	-62.2	-42.4	174.9	171.8	61.9	0	0	0	111.1	D69 E70 T76 V132 L133 M136	D69-L72 WeakPolarHBondContact O-CB 3.29Å; D69-L72 PolarHBondContact O-N 2.92Å; E70-L72 PolarHBondContact O-N 3.3Å; L72-T76 VanDerWaalsContact O-CB 3.31Å; L72-T76 WeakPolarHBondContact O-CB 3.43Å; L72-T76 PolarHBondContact O-N 2.94Å; L72-T76 PolarHBondContact O-OG1 2.98Å; L72-V132 HydrophobicContact CD1-CG1 3.99Å; L72-L133 HydrophobicContact CG-CD1 4.27Å; L72-M136 HydrophobicContact CD2-CB 4.37Å
73	F	98.1	Very high	98.2	Very high	41 Å²	41	63.7 Å²	63.7	18%	0.18	32%	0.323	C	S	.	.	H	α-helix	trans	-58.2	-49.2	175.8	-176	-91	0	0	0	111.2	D69 E70 H71 T76 H77 L133 M136 F141 F144 L148	D69-F73 PolarHBondContact O-N 3.17Å; E70-F73 WeakPolarHBondContact O-CB 3.42Å; E70-F73 PolarHBondContact O-N 3.43Å; H71-F73 VanDerWaalsContact C-N 3.33Å; F73-T76 PolarHBondContact O-N 2.78Å; F73-H77 AromaticContact CD1-ND1 3.91Å; F73-H77 AromaticContact CD2-CE1 3.69Å; F73-H77 AromaticContact CE1-CE1 3.69Å; F73-H77 AromaticContact CE1-ND1 3.83Å; F73-H77 AromaticContact CE2-CE1 3.3Å; F73-H77 WeakPolarHBondContact CE2-CE1 3.47Å; F73-H77 AromaticContact CZ-CE1 3.29Å; F73-H77 WeakPolarHBondContact CZ-CE1 3.35Å; F73-H77 AromaticContact CZ-ND1 3.91Å; F73-H77 AromaticContact CZ-NE2 3.83Å; F73-H77 PolarHBondContact O-N 2.94Å; F73-H77 PolarHBondContact O-ND1 3.43Å; F73-L133 HydrophobicContact CD2-CD1 4.4Å; F73-M136 HydrophobicContact CD2-CE 4.27Å; F73-F141 HydrophobicContact CD2-CE2 4.27Å; F73-F141 AromaticContact CE2-CE2 3.96Å; F73-F141 HydrophobicContact CE2-CE2 3.96Å; F73-F144 HydrophobicContact CB-CE2 3.98Å; F73-F144 HydrophobicContact CB-CZ 3.84Å; F73-F144 HydrophobicContact CD1-CE2 4.27Å; F73-F144 HydrophobicContact CD2-CE2 4.19Å; F73-F144 HydrophobicContact CD2-CZ 4.19Å; F73-F144 AromaticContact CG-CE2 3.9Å; F73-F144 HydrophobicContact CG-CE2 3.9Å; F73-F144 HydrophobicContact CG-CZ 4.08Å; F73-L148 HydrophobicContact CE1-CD1 4.01Å; F73-L148 HydrophobicContact CE1-CD2 4.25Å; F73-L148 HydrophobicContact CE2-CD1 4.5Å; F73-L148 HydrophobicContact CZ-CD1 3.91Å
74	I	98.3	Very high	98.3	Very high	28 Å²	28	57.1 Å²	57.1	14%	0.144	29%	0.294	C	S	.	.	H	α-helix	trans	-61.5	-53.7	179.2	-68.6	163.5	0	0	0	111.3	E57 L58 E70 H71 T76 H77 Q78	E57-I74 VanDerWaalsContact O-CD1 3.31Å; E57-I74 WeakPolarHBondContact O-CD1 3.38Å; L58-I74 HydrophobicContact CD1-CD1 3.92Å; L58-I74 HydrophobicContact CG-CD1 4.08Å; E70-I74 HydrophobicContact CG-CD1 4.1Å; E70-I74 WeakPolarHBondContact O-CG1 3.42Å; E70-I74 PolarHBondContact O-N 3.49Å; H71-I74 PolarHBondContact O-N 3.48Å; I74-T76 VanDerWaalsContact C-N 3.27Å; I74-T76 PolarHBondContact O-N 3.42Å; I74-H77 PolarHBondContact O-N 2.99Å; I74-H77 VanDerWaalsContact O-N 3.16Å; I74-Q78 HydrophobicContact CG2-CG 4.24Å; I74-Q78 WeakPolarHBondContact O-CG 3.28Å; I74-Q78 PolarHBondContact O-N 3.24Å
75	I	98.7	Very high	98.4	Very high	67 Å²	67	60.1 Å²	60.1	34%	0.344	29%	0.287	S	S	.	.	H	α-helix	trans	-59.6	-39.9	-177.9	-71.5	-65.8	0	0	0	111.4	Q56 H71 H77 Q78 A79	Q56-I75 HydrophobicContact CG-CD1 3.53Å; Q56-I75 HydrophobicContact CG-CG1 4.29Å; H71-I75 VanDerWaalsContact CE1-CG1 3.47Å; H71-I75 WeakPolarHBondContact CE1-CG1 3.34Å; H71-I75 WeakPolarHBondContact O-CG1 3.38Å; H71-I75 PolarHBondContact O-N 3.16Å; I75-H77 PolarHBondContact O-N 3.37Å; I75-Q78 PolarHBondContact O-N 3.3Å; I75-A79 WeakPolarHBondContact O-CB 3.31Å; I75-A79 PolarHBondContact O-N 3.49Å
76	T	98.4	Very high	98.5	Very high	7 Å²	7	59.7 Å²	59.7	4%	0.043	28%	0.282	C	S	.	.	H	α-helix	trans	-60.3	-47.7	177.7	-61.3	0	0	0	0	111.2	L72 F73 I74 A79 Y80 Q129 L133	L72-T76 VanDerWaalsContact O-CB 3.31Å; L72-T76 WeakPolarHBondContact O-CB 3.43Å; L72-T76 PolarHBondContact O-N 2.94Å; L72-T76 PolarHBondContact O-OG1 2.98Å; F73-T76 PolarHBondContact O-N 2.78Å; I74-T76 VanDerWaalsContact C-N 3.27Å; I74-T76 PolarHBondContact O-N 3.42Å; T76-A79 PolarHBondContact O-N 3.19Å; T76-Y80 HydrophobicContact CG2-CD2 3.86Å; T76-Y80 HydrophobicContact CG2-CE2 3.57Å; T76-Y80 WeakPolarHBondContact O-CD2 3.48Å; T76-Y80 PolarHBondContact O-N 3.34Å; T76-Q129 PolarHBondContact O-NE2 3.27Å; T76-Q129 VanDerWaalsContact O-NE2 3.16Å; T76-L133 HydrophobicContact CG2-CB 4.04Å; T76-L133 HydrophobicContact CG2-CD2 4.08Å; T76-L133 HydrophobicContact CG2-CG 4.48Å
77	H	98.3	Very high	98.5	Very high	80 Å²	80	53.9 Å²	53.9	37%	0.37	26%	0.257	S	S	.	.	H	α-helix	trans	-67.7	-40	179.8	-71.6	80.2	0	0	0	111.7	F73 I74 I75 A79 Y80 E81	F73-H77 AromaticContact CD1-ND1 3.91Å; F73-H77 AromaticContact CD2-CE1 3.69Å; F73-H77 AromaticContact CE1-CE1 3.69Å; F73-H77 AromaticContact CE1-ND1 3.83Å; F73-H77 AromaticContact CE2-CE1 3.3Å; F73-H77 WeakPolarHBondContact CE2-CE1 3.47Å; F73-H77 AromaticContact CZ-CE1 3.29Å; F73-H77 WeakPolarHBondContact CZ-CE1 3.35Å; F73-H77 AromaticContact CZ-ND1 3.91Å; F73-H77 AromaticContact CZ-NE2 3.83Å; F73-H77 PolarHBondContact O-N 2.94Å; F73-H77 PolarHBondContact O-ND1 3.43Å; I74-H77 PolarHBondContact O-N 2.99Å; I74-H77 VanDerWaalsContact O-N 3.16Å; I75-H77 PolarHBondContact O-N 3.37Å; H77-A79 VanDerWaalsContact C-N 3.34Å; H77-A79 PolarHBondContact O-N 3.42Å; H77-Y80 WeakPolarHBondContact O-CB 3.31Å; H77-Y80 PolarHBondContact O-N 3.05Å; H77-E81 WeakPolarHBondContact O-CG 3.13Å; H77-E81 PolarHBondContact O-N 3.18Å
78	Q	98.5	Very high	98.6	Very high	55 Å²	55	53.2 Å²	53.2	26%	0.257	25%	0.254	S	S	.	.	H	α-helix	trans	-60	-43.2	174.5	-72.3	177.4	-16.9	0	0	111.9	A55 I74 I75 E81 L82	A55-Q78 PolarHBondContact O-NE2 2.81Å; I74-Q78 HydrophobicContact CG2-CG 4.24Å; I74-Q78 WeakPolarHBondContact O-CG 3.28Å; I74-Q78 PolarHBondContact O-N 3.24Å; I75-Q78 PolarHBondContact O-N 3.3Å; Q78-E81 PolarHBondContact O-N 2.77Å; Q78-L82 WeakPolarHBondContact O-CG 3.25Å; Q78-L82 PolarHBondContact O-N 3.26Å
79	A	98.6	Very high	98.6	Very high	30 Å²	30	54.7 Å²	54.7	25%	0.248	25%	0.253	C	S	.	.	H	α-helix	trans	-63.3	-41.7	175.6	0	0	0	0	0	112.2	I75 T76 H77 L82 W83	I75-A79 WeakPolarHBondContact O-CB 3.31Å; I75-A79 PolarHBondContact O-N 3.49Å; T76-A79 PolarHBondContact O-N 3.19Å; H77-A79 VanDerWaalsContact C-N 3.34Å; H77-A79 PolarHBondContact O-N 3.42Å; A79-L82 PolarHBondContact O-N 3.01Å; A79-W83 PolarHBondContact O-N 3.44Å; A79-W83 VanDerWaalsContact O-N 3.17Å
80	Y	98.6	Very high	98.6	Very high	12 Å²	12	53.5 Å²	53.5	5%	0.047	25%	0.247	C	C	.	.	H	α-helix	trans	-58.6	-46.8	172.2	-82.9	-66	0	0	0	112	T76 H77 L82 W83 F84 L126 Q129 F130 W325	T76-Y80 HydrophobicContact CG2-CD2 3.86Å; T76-Y80 HydrophobicContact CG2-CE2 3.57Å; T76-Y80 WeakPolarHBondContact O-CD2 3.48Å; T76-Y80 PolarHBondContact O-N 3.34Å; H77-Y80 WeakPolarHBondContact O-CB 3.31Å; H77-Y80 PolarHBondContact O-N 3.05Å; Y80-L82 VanDerWaalsContact C-N 3.35Å; Y80-L82 PolarHBondContact O-N 2.5Å; Y80-W83 PolarHBondContact O-N 3.18Å; Y80-W83 VanDerWaalsContact O-N 3.15Å; Y80-F84 HydrophobicContact CD1-CZ 4.29Å; Y80-F84 WeakPolarHBondContact O-CD2 3.42Å; Y80-F84 VanDerWaalsContact O-CG 3.28Å; Y80-F84 WeakPolarHBondContact O-CG 3.28Å; Y80-F84 PolarHBondContact O-N 3.43Å; Y80-L126 HydrophobicContact CD1-CB 4.3Å; Y80-L126 HydrophobicContact CD1-CD1 4.31Å; Y80-L126 HydrophobicContact CD1-CD2 3.52Å; Y80-L126 HydrophobicContact CD1-CG 4.24Å; Y80-L126 HydrophobicContact CE1-CB 3.89Å; Y80-L126 HydrophobicContact CE1-CD2 3.78Å; Y80-L126 HydrophobicContact CE1-CG 4.3Å; Y80-L126 WeakPolarHBondContact CE1-O 3Å; Y80-L126 PolarHBondContact OH-O 2.91Å; Y80-L126 VanDerWaalsContact OH-O 3.05Å; Y80-Q129 HydrophobicContact CE1-CB 4.3Å; Y80-Q129 HydrophobicContact CE1-CG 4.48Å; Y80-Q129 HydrophobicContact CE2-CG 4.23Å; Y80-F130 WeakPolarHBondContact OH-CD2 3.29Å; Y80-F130 WeakPolarHBondContact OH-CG 3.26Å; Y80-F130 PolarHBondContact OH-N 3.08Å; Y80-W325 AromaticContact CD1-NE1 3.9Å; Y80-W325 AromaticContact CE1-NE1 3.36Å; Y80-W325 AromaticContact CZ-NE1 3.99Å
81	E	98.5	Very high	98.6	Very high	59 Å²	59	53.6 Å²	53.6	28%	0.276	25%	0.247	S	C	.	.	H	α-helix	trans	-66.6	-33.5	-178.3	-70.6	-66.2	161.4	0	0	112.6	H77 Q78 F84 K85 S156 Q158	H77-E81 WeakPolarHBondContact O-CG 3.13Å; H77-E81 PolarHBondContact O-N 3.18Å; Q78-E81 PolarHBondContact O-N 2.77Å; E81-F84 PolarHBondContact O-N 3.21Å; E81-K85 PolarHBondContact O-N 2.92Å; E81-S156 WeakPolarHBondContact OE1-CB 3.2Å; E81-S156 PolarHBondContact OE1-OG 3.49Å; E81-Q158 PolarHBondContact O-NE2 3.19Å; E81-Q158 WeakPolarHBondContact OE2-CB 3.34Å; E81-Q158 PolarHBondContact OE2-NE2 2.91Å
82	L	98.8	Very high	98.6	Very high	102 Å²	102	52 Å²	52	53%	0.534	24%	0.242	S	C	.	.	H	α-helix	trans	-62.8	-43.3	170.7	-72.3	176.3	0	0	0	111.7	Q78 A79 Y80 K85 Q86	Q78-L82 WeakPolarHBondContact O-CG 3.25Å; Q78-L82 PolarHBondContact O-N 3.26Å; A79-L82 PolarHBondContact O-N 3.01Å; Y80-L82 VanDerWaalsContact C-N 3.35Å; Y80-L82 PolarHBondContact O-N 2.5Å; L82-K85 WeakPolarHBondContact O-CB 3.46Å; L82-K85 PolarHBondContact O-N 2.87Å; L82-Q86 PolarHBondContact O-N 3.04Å; L82-Q86 VanDerWaalsContact O-N 3.08Å
83	W	98.8	Very high	98.6	Very high	91 Å²	91	51.3 Å²	51.3	35%	0.345	24%	0.24	S	C	.	.	H	α-helix	trans	-70.3	-36.7	177	-74.9	123.9	0	0	0	113	A79 Y80 K85 Q86 I87 I122 L125 L126	A79-W83 PolarHBondContact O-N 3.44Å; A79-W83 VanDerWaalsContact O-N 3.17Å; Y80-W83 PolarHBondContact O-N 3.18Å; Y80-W83 VanDerWaalsContact O-N 3.15Å; W83-K85 VanDerWaalsContact C-N 3.28Å; W83-K85 PolarHBondContact O-N 3.24Å; W83-Q86 HydrophobicContact CE3-CB 4.27Å; W83-Q86 PolarHBondContact O-N 2.98Å; W83-I87 WeakPolarHBondContact O-CG1 3.31Å; W83-I87 PolarHBondContact O-N 3.09Å; W83-I122 HydrophobicContact CB-CG2 3.88Å; W83-I122 HydrophobicContact CD2-CG2 3.89Å; W83-I122 HydrophobicContact CE3-CB 4.39Å; W83-I122 HydrophobicContact CE3-CD1 4.12Å; W83-I122 HydrophobicContact CE3-CG1 3.92Å; W83-I122 HydrophobicContact CE3-CG2 3.56Å; W83-I122 HydrophobicContact CG-CG2 4.05Å; W83-I122 HydrophobicContact CZ3-CD1 4.22Å; W83-I122 HydrophobicContact CZ3-CG1 3.95Å; W83-I122 HydrophobicContact CZ3-CG2 4.38Å; W83-L125 HydrophobicContact CH2-CD2 4.36Å; W83-L125 HydrophobicContact CZ2-CD2 3.55Å; W83-L126 HydrophobicContact CB-CD1 4.23Å; W83-L126 HydrophobicContact CB-CD2 3.61Å; W83-L126 HydrophobicContact CB-CG 4.29Å; W83-L126 HydrophobicContact CG-CD2 3.75Å
84	F	98.7	Very high	98.6	Very high	6 Å²	6	49.4 Å²	49.4	3%	0.026	23%	0.232	C	C	.	.	H	α-helix	trans	-60.1	-41.1	172.1	-65.1	-28.9	0	0	0	111.2	Y80 E81 Q86 I87 L88 L126 Q158 F159 L162 W325	Y80-F84 HydrophobicContact CD1-CZ 4.29Å; Y80-F84 WeakPolarHBondContact O-CD2 3.42Å; Y80-F84 VanDerWaalsContact O-CG 3.28Å; Y80-F84 WeakPolarHBondContact O-CG 3.28Å; Y80-F84 PolarHBondContact O-N 3.43Å; E81-F84 PolarHBondContact O-N 3.21Å; F84-Q86 PolarHBondContact O-N 3.2Å; F84-I87 PolarHBondContact O-N 3.06Å; F84-L88 WeakPolarHBondContact O-CB 3.46Å; F84-L88 WeakPolarHBondContact O-CG 3.35Å; F84-L88 PolarHBondContact O-N 2.91Å; F84-L126 HydrophobicContact CD1-CD1 3.98Å; F84-L126 HydrophobicContact CE1-CD1 3.67Å; F84-Q158 HydrophobicContact CB-CB 3.9Å; F84-F159 HydrophobicContact CE1-CD2 4.28Å; F84-F159 HydrophobicContact CE2-CB 4.41Å; F84-F159 HydrophobicContact CE2-CD2 4.32Å; F84-F159 AromaticContact CZ-CD2 3.93Å; F84-F159 HydrophobicContact CZ-CD2 3.93Å; F84-L162 HydrophobicContact CD1-CD2 4.36Å; F84-W325 HydrophobicContact CZ-CZ2 4.03Å
85	K	98.8	Very high	98.7	Very high	134 Å²	134	48.5 Å²	48.5	58%	0.583	23%	0.227	S	C	*	.	H	α-helix	trans	-60.2	-44.1	173.7	-166.9	173.3	179.7	175.7	0	112.2	E81 L82 W83 L88 W89	E81-K85 PolarHBondContact O-N 2.92Å; L82-K85 WeakPolarHBondContact O-CB 3.46Å; L82-K85 PolarHBondContact O-N 2.87Å; W83-K85 VanDerWaalsContact C-N 3.28Å; W83-K85 PolarHBondContact O-N 3.24Å; K85-L88 PolarHBondContact O-N 2.98Å; K85-W89 WeakPolarHBondContact O-CB 3.35Å; K85-W89 PolarHBondContact O-N 2.71Å
86	Q	98.9	Very high	98.6	Very high	71 Å²	71	49.9 Å²	49.9	33%	0.332	23%	0.232	S	C	.	.	H	α-helix	trans	-63.2	-43.6	176.2	-174	62.1	41.6	0	0	111.6	L82 W83 F84 L88 W89 E90 I122	L82-Q86 PolarHBondContact O-N 3.04Å; L82-Q86 VanDerWaalsContact O-N 3.08Å; W83-Q86 HydrophobicContact CE3-CB 4.27Å; W83-Q86 PolarHBondContact O-N 2.98Å; F84-Q86 PolarHBondContact O-N 3.2Å; Q86-L88 PolarHBondContact O-N 3.04Å; Q86-W89 WeakPolarHBondContact O-CB 3.38Å; Q86-W89 PolarHBondContact O-N 2.91Å; Q86-E90 PolarHBondContact NE2-OE1 2.91Å; Q86-E90 WeakPolarHBondContact O-CG 3.27Å; Q86-E90 PolarHBondContact O-N 3.09Å; Q86-I122 HydrophobicContact CB-CD1 4.31Å; Q86-I122 HydrophobicContact CG-CD1 3.7Å
87	I	98.8	Very high	98.6	Very high	1 Å²	1	50.2 Å²	50.2	1%	0.005	23%	0.233	C	C	.	.	H	α-helix	trans	-61.7	-45.1	177.5	-67.1	164	0	0	0	110.5	W83 F84 W89 E90 L91 V119 I122 F123 L126 L162	W83-I87 WeakPolarHBondContact O-CG1 3.31Å; W83-I87 PolarHBondContact O-N 3.09Å; F84-I87 PolarHBondContact O-N 3.06Å; I87-W89 VanDerWaalsContact C-N 3.29Å; I87-W89 PolarHBondContact O-N 3.02Å; I87-E90 PolarHBondContact O-N 3.24Å; I87-L91 VanDerWaalsContact O-CB 3.22Å; I87-L91 WeakPolarHBondContact O-CB 3.32Å; I87-L91 PolarHBondContact O-N 3.35Å; I87-V119 HydrophobicContact CG1-CG1 4.39Å; I87-V119 HydrophobicContact CG2-CG1 3.75Å; I87-V119 HydrophobicContact CG2-CG2 4.18Å; I87-I122 HydrophobicContact CD1-CB 4.39Å; I87-I122 HydrophobicContact CD1-CG2 3.74Å; I87-I122 HydrophobicContact CG1-CB 4.19Å; I87-I122 HydrophobicContact CG1-CD1 4.22Å; I87-I122 HydrophobicContact CG1-CG2 3.8Å; I87-F123 HydrophobicContact CD1-CD1 4.37Å; I87-F123 HydrophobicContact CD1-CD2 4.22Å; I87-F123 HydrophobicContact CD1-CE1 4.15Å; I87-F123 HydrophobicContact CD1-CE2 4Å; I87-F123 HydrophobicContact CD1-CG 4.41Å; I87-F123 HydrophobicContact CD1-CZ 3.98Å; I87-F123 HydrophobicContact CG2-CE2 4.28Å; I87-L126 HydrophobicContact CD1-CD1 3.97Å; I87-L162 HydrophobicContact CG2-CD1 3.46Å; I87-L162 VanDerWaalsContact CG2-CD1 3.46Å; I87-L162 HydrophobicContact CG2-CD2 4.48Å
88	L	98.8	Very high	98.6	Very high	13 Å²	13	47 Å²	47	7%	0.068	22%	0.218	C	C	.	.	H	α-helix	trans	-59.4	-41.3	176.3	-74.5	170.6	0	0	0	111.5	F84 K85 Q86 L91 D92 Q158 L161 L162 K165	F84-L88 WeakPolarHBondContact O-CB 3.46Å; F84-L88 WeakPolarHBondContact O-CG 3.35Å; F84-L88 PolarHBondContact O-N 2.91Å; K85-L88 PolarHBondContact O-N 2.98Å; Q86-L88 PolarHBondContact O-N 3.04Å; L88-L91 PolarHBondContact O-N 3.36Å; L88-D92 WeakPolarHBondContact O-CB 3.43Å; L88-D92 PolarHBondContact O-N 3.37Å; L88-Q158 HydrophobicContact CD1-CB 3.78Å; L88-Q158 HydrophobicContact CD1-CG 4.01Å; L88-L161 HydrophobicContact CD1-CB 4.26Å; L88-L161 HydrophobicContact CD1-CD1 4.45Å; L88-L161 HydrophobicContact CD2-CB 4.01Å; L88-L162 HydrophobicContact CD2-CB 4.21Å; L88-K165 HydrophobicContact CD2-CD 3.67Å
89	W	98.8	Very high	98.6	Very high	189 Å²	189	47.9 Å²	47.9	72%	0.716	22%	0.222	S	C	*	.	H	α-helix	trans	-61.7	-46.5	176.2	-171.8	-93.7	0	0	0	112.6	K85 Q86 I87 S93	K85-W89 WeakPolarHBondContact O-CB 3.35Å; K85-W89 PolarHBondContact O-N 2.71Å; Q86-W89 WeakPolarHBondContact O-CB 3.38Å; Q86-W89 PolarHBondContact O-N 2.91Å; I87-W89 VanDerWaalsContact C-N 3.29Å; I87-W89 PolarHBondContact O-N 3.02Å; W89-S93 WeakPolarHBondContact O-CB 3.4Å; W89-S93 PolarHBondContact O-N 3.01Å; W89-S93 VanDerWaalsContact O-N 3.14Å; W89-S93 PolarHBondContact O-OG 3.39Å
90	E	98.8	Very high	98.4	Very high	6 Å²	6	49.6 Å²	49.6	3%	0.028	23%	0.227	C	C	.	.	H	α-helix	trans	-62.7	-46.8	175	-62.3	-57.5	162.3	0	0	111.2	Q86 I87 S93 V94 R115 R118 V119	Q86-E90 PolarHBondContact NE2-OE1 2.91Å; Q86-E90 WeakPolarHBondContact O-CG 3.27Å; Q86-E90 PolarHBondContact O-N 3.09Å; I87-E90 PolarHBondContact O-N 3.24Å; E90-S93 PolarHBondContact O-N 2.94Å; E90-S93 PolarHBondContact O-OG 2.81Å; E90-V94 WeakPolarHBondContact O-CG2 3.43Å; E90-V94 PolarHBondContact O-N 3Å; E90-R115 WeakPolarHBondContact OE2-CD 3.3Å; E90-R115 VanDerWaalsContact OE2-CG 3.23Å; E90-R115 WeakPolarHBondContact OE2-CG 3.29Å; E90-R115 IonicContact OE2-NE 3.97Å; E90-R118 VanDerWaalsContact OE1-CD 3.25Å; E90-R118 WeakPolarHBondContact OE1-CD 3.44Å; E90-R118 IonicContact OE1-CZ 3.69Å; E90-R118 IonicContact OE1-NE 3.58Å; E90-R118 IonicContact OE1-NH1 2.74Å; E90-R118 PolarHBondContact OE1-NH1 3.47Å; E90-R118 IonicContact OE2-NH1 3.13Å; E90-R118 PolarHBondContact OE2-NH1 3.12Å; E90-R118 VanDerWaalsContact OE2-NH1 3.13Å; E90-V119 HydrophobicContact CB-CG2 3.67Å; E90-V119 HydrophobicContact CG-CG2 4.24Å
91	L	98.6	Very high	98.3	Very high	5 Å²	5	50.1 Å²	50.1	3%	0.026	24%	0.236	C	C	.	.	H	α-helix	trans	-62.1	-48.5	-177.3	-178.7	60.5	0	0	0	111.8	I87 L88 S93 V94 R95 L162 K165 I166 L202	I87-L91 VanDerWaalsContact O-CB 3.22Å; I87-L91 WeakPolarHBondContact O-CB 3.32Å; I87-L91 PolarHBondContact O-N 3.35Å; L88-L91 PolarHBondContact O-N 3.36Å; L91-S93 VanDerWaalsContact C-N 3.3Å; L91-S93 PolarHBondContact O-N 3.2Å; L91-V94 PolarHBondContact O-N 3.16Å; L91-V94 VanDerWaalsContact O-N 3.16Å; L91-R95 HydrophobicContact CD1-CG 4.42Å; L91-R95 HydrophobicContact CG-CG 4.49Å; L91-R95 VanDerWaalsContact O-CG 3.29Å; L91-R95 WeakPolarHBondContact O-CG 3.36Å; L91-R95 PolarHBondContact O-N 2.7Å; L91-L162 HydrophobicContact CD2-CD1 4.06Å; L91-K165 HydrophobicContact CD2-CB 3.55Å; L91-K165 HydrophobicContact CG-CB 4.35Å; L91-I166 HydrophobicContact CD2-CG1 3.84Å; L91-L202 HydrophobicContact CD1-CB 4.07Å; L91-L202 HydrophobicContact CD1-CD1 4.43Å; L91-L202 HydrophobicContact CD1-CD2 3.71Å; L91-L202 HydrophobicContact CD1-CG 4.29Å
92	D	98.7	Very high	98.1	Very high	55 Å²	55	51.1 Å²	51.1	29%	0.294	24%	0.241	S	C	.	.	H	α-helix	trans	-63.2	-39.6	178.2	-76.5	-21	0	0	0	111.2	L88 V94 R95 E96 K165	L88-D92 WeakPolarHBondContact O-CB 3.43Å; L88-D92 PolarHBondContact O-N 3.37Å; D92-V94 VanDerWaalsContact C-N 3.28Å; D92-V94 PolarHBondContact O-N 3Å; D92-R95 PolarHBondContact O-N 3.06Å; D92-R95 IonicContact OD1-CZ 3.02Å; D92-R95 IonicContact OD1-NH1 2.83Å; D92-R95 PolarHBondContact OD1-NH1 3.31Å; D92-E96 WeakPolarHBondContact O-CB 3.23Å; D92-E96 PolarHBondContact O-N 3.32Å; D92-K165 VanDerWaalsContact CG-NZ 3.3Å; D92-K165 WeakPolarHBondContact OD1-CD 3.33Å; D92-K165 WeakPolarHBondContact OD1-CE 3.46Å; D92-K165 IonicContact OD1-NZ 3.7Å; D92-K165 PolarHBondContact OD1-NZ 3.41Å; D92-K165 IonicContact OD2-NZ 3.22Å; D92-K165 PolarHBondContact OD2-NZ 3.29Å; D92-K165 VanDerWaalsContact OD2-NZ 3.07Å
93	S	98.7	Very high	97.9	Very high	26 Å²	26	46.3 Å²	46.3	18%	0.182	22%	0.216	C	C	.	.	H	α-helix	trans	-65.7	-30.7	176.2	84.2	0	0	0	0	113.3	W89 E90 L91 I97 R115	W89-S93 WeakPolarHBondContact O-CB 3.4Å; W89-S93 PolarHBondContact O-N 3.01Å; W89-S93 VanDerWaalsContact O-N 3.14Å; W89-S93 PolarHBondContact O-OG 3.39Å; E90-S93 PolarHBondContact O-N 2.94Å; E90-S93 PolarHBondContact O-OG 2.81Å; L91-S93 VanDerWaalsContact C-N 3.3Å; L91-S93 PolarHBondContact O-N 3.2Å; S93-I97 WeakPolarHBondContact O-CD1 3.32Å; S93-I97 VanDerWaalsContact O-CG1 3.31Å; S93-I97 WeakPolarHBondContact O-CG1 3.41Å; S93-I97 PolarHBondContact O-N 2.84Å; S93-R115 VanDerWaalsContact OG-CD 3.27Å; S93-R115 WeakPolarHBondContact OG-CD 3.45Å; S93-R115 PolarHBondContact OG-NH1 2.85Å
94	V	98.7	Very high	97.6	Very high	1 Å²	1	49 Å²	49	1%	0.006	23%	0.226	C	C	.	.	H	α-helix	trans	-77.2	-46.2	174.8	170.2	0	0	0	0	109.9	E90 L91 D92 E96 I97 F98 V112 R115 M116 L202	E90-V94 WeakPolarHBondContact O-CG2 3.43Å; E90-V94 PolarHBondContact O-N 3Å; L91-V94 PolarHBondContact O-N 3.16Å; L91-V94 VanDerWaalsContact O-N 3.16Å; D92-V94 VanDerWaalsContact C-N 3.28Å; D92-V94 PolarHBondContact O-N 3Å; V94-E96 PolarHBondContact O-N 3.35Å; V94-I97 WeakPolarHBondContact O-CB 3.34Å; V94-I97 PolarHBondContact O-N 2.95Å; V94-F98 HydrophobicContact CG1-CD2 4.03Å; V94-F98 HydrophobicContact CG1-CE2 3.83Å; V94-F98 WeakPolarHBondContact O-CD2 3.28Å; V94-F98 PolarHBondContact O-N 3.24Å; V94-V112 HydrophobicContact CG1-CG1 4.03Å; V94-R115 HydrophobicContact CG2-CB 3.75Å; V94-M116 HydrophobicContact CB-SD 4.16Å; V94-M116 HydrophobicContact CG1-CG 4.39Å; V94-M116 HydrophobicContact CG1-SD 3.94Å; V94-M116 HydrophobicContact CG2-CG 4.38Å; V94-M116 HydrophobicContact CG2-SD 3.93Å; V94-L202 HydrophobicContact CG1-CD1 4.17Å
95	R	98.6	Very high	97.3	Very high	8 Å²	8	49.2 Å²	49.2	3%	0.03	23%	0.227	C	C	.	.	H	α-helix	trans	-52.2	-46.6	174.9	-71.8	170.5	62.1	-123	-1.8	110.8	L91 D92 I97 F98 Q99 K165 E199 Q200 L205	L91-R95 HydrophobicContact CD1-CG 4.42Å; L91-R95 HydrophobicContact CG-CG 4.49Å; L91-R95 VanDerWaalsContact O-CG 3.29Å; L91-R95 WeakPolarHBondContact O-CG 3.36Å; L91-R95 PolarHBondContact O-N 2.7Å; D92-R95 PolarHBondContact O-N 3.06Å; D92-R95 IonicContact OD1-CZ 3.02Å; D92-R95 IonicContact OD1-NH1 2.83Å; D92-R95 PolarHBondContact OD1-NH1 3.31Å; R95-I97 PolarHBondContact O-N 3.42Å; R95-F98 PolarHBondContact O-N 3.44Å; R95-F98 VanDerWaalsContact O-N 3.08Å; R95-Q99 VanDerWaalsContact O-CG 3.3Å; R95-Q99 WeakPolarHBondContact O-CG 3.49Å; R95-Q99 PolarHBondContact O-N 2.87Å; R95-K165 VanDerWaalsContact NH1-NZ 3.12Å; R95-E199 IonicContact CZ-OE2 3.76Å; R95-E199 IonicContact NH1-OE2 2.7Å; R95-E199 PolarHBondContact NH1-OE2 3.14Å; R95-E199 VanDerWaalsContact NH2-CB 3.29Å; R95-E199 IonicContact NH2-OE2 3.51Å; R95-E199 PolarHBondContact NH2-OE2 3.44Å; R95-Q200 PolarHBondContact NE-O 3.47Å; R95-Q200 PolarHBondContact NH2-O 2.84Å; R95-L205 HydrophobicContact CB-CD1 3.75Å; R95-L205 HydrophobicContact CG-CD1 3.92Å
96	E	98.4	Very high	96.9	Very high	96 Å²	96	45.1 Å²	45.1	45%	0.449	21%	0.21	S	C	.	.	H	α-helix	trans	-58.6	-44.4	177.1	-178.6	53.9	-137.7	0	0	112.4	D92 V94 F98 Q99 N100	D92-E96 WeakPolarHBondContact O-CB 3.23Å; D92-E96 PolarHBondContact O-N 3.32Å; V94-E96 PolarHBondContact O-N 3.35Å; E96-F98 PolarHBondContact O-N 2.69Å; E96-Q99 PolarHBondContact O-N 3.07Å; E96-Q99 VanDerWaalsContact O-N 3.14Å; E96-N100 PolarHBondContact O-N 3.24Å; E96-N100 PolarHBondContact O-ND2 3.3Å; E96-N100 PolarHBondContact O-OD1 3.4Å; E96-N100 VanDerWaalsContact O-OD1 3.06Å; E96-N100 PolarHBondContact OE1-ND2 3.41Å
97	I	98.2	Very high	96.5	Very high	14 Å²	14	48.5 Å²	48.5	7%	0.072	22%	0.22	C	C	.	.	H	α-helix	trans	-59.1	-34.4	176.4	-70.7	164.9	0	0	0	112.1	S93 V94 R95 N100 H102 V103 K111 V112	S93-I97 WeakPolarHBondContact O-CD1 3.32Å; S93-I97 VanDerWaalsContact O-CG1 3.31Å; S93-I97 WeakPolarHBondContact O-CG1 3.41Å; S93-I97 PolarHBondContact O-N 2.84Å; V94-I97 WeakPolarHBondContact O-CB 3.34Å; V94-I97 PolarHBondContact O-N 2.95Å; R95-I97 PolarHBondContact O-N 3.42Å; I97-N100 PolarHBondContact O-OD1 3.48Å; I97-N100 VanDerWaalsContact O-OD1 3.09Å; I97-H102 HydrophobicContact CG2-CB 4.17Å; I97-H102 PolarHBondContact O-N 3.39Å; I97-V103 HydrophobicContact CG2-CB 4.16Å; I97-V103 PolarHBondContact O-N 3.47Å; I97-K111 HydrophobicContact CD1-CD 4.03Å; I97-V112 HydrophobicContact CB-CG2 4.42Å; I97-V112 HydrophobicContact CD1-CG2 4.2Å; I97-V112 HydrophobicContact CG2-CG2 3.73Å
98	F	97.9	Very high	96.3	Very high	14 Å²	14	49.6 Å²	49.6	6%	0.061	23%	0.226	C	C	.	.	H	α-helix	trans	-76.2	-42.6	174.6	-79.8	-106.8	0	0	0	111.7	V94 R95 E96 G101 V103 V112 L205 V206 W209 L311	V94-F98 HydrophobicContact CG1-CD2 4.03Å; V94-F98 HydrophobicContact CG1-CE2 3.83Å; V94-F98 WeakPolarHBondContact O-CD2 3.28Å; V94-F98 PolarHBondContact O-N 3.24Å; R95-F98 PolarHBondContact O-N 3.44Å; R95-F98 VanDerWaalsContact O-N 3.08Å; E96-F98 PolarHBondContact O-N 2.69Å; F98-G101 PolarHBondContact O-N 3.16Å; F98-V103 HydrophobicContact CB-CG1 4.43Å; F98-V103 HydrophobicContact CD1-CB 4.23Å; F98-V103 HydrophobicContact CD1-CG1 3.94Å; F98-V103 HydrophobicContact CD1-CG2 3.98Å; F98-V103 HydrophobicContact CD2-CB 4.38Å; F98-V103 HydrophobicContact CD2-CG2 4.2Å; F98-V103 HydrophobicContact CE1-CB 4.48Å; F98-V103 HydrophobicContact CE1-CG1 4.44Å; F98-V103 HydrophobicContact CE1-CG2 3.73Å; F98-V103 HydrophobicContact CE2-CG2 3.98Å; F98-V103 HydrophobicContact CG-CB 4.18Å; F98-V103 HydrophobicContact CG-CG1 4.15Å; F98-V103 HydrophobicContact CG-CG2 4.21Å; F98-V103 HydrophobicContact CZ-CG2 3.73Å; F98-V112 HydrophobicContact CE2-CG1 3.78Å; F98-V112 HydrophobicContact CE2-CG2 4.26Å; F98-V112 HydrophobicContact CZ-CG1 4.29Å; F98-L205 HydrophobicContact CB-CB 3.81Å; F98-L205 HydrophobicContact CB-CD1 4.17Å; F98-L205 HydrophobicContact CB-CD2 4.04Å; F98-L205 HydrophobicContact CB-CG 4.22Å; F98-L205 HydrophobicContact CD1-CB 4.18Å; F98-L205 WeakPolarHBondContact CD1-O 3.5Å; F98-L205 HydrophobicContact CG-CB 4.15Å; F98-V206 HydrophobicContact CE1-CG2 4.39Å; F98-V206 HydrophobicContact CZ-CG2 4.44Å; F98-W209 HydrophobicContact CD1-CB 3.95Å; F98-W209 HydrophobicContact CD1-CG 4.43Å; F98-W209 HydrophobicContact CE1-CB 3.63Å; F98-W209 HydrophobicContact CE1-CD2 4.17Å; F98-W209 AromaticContact CE1-CG 3.75Å; F98-W209 HydrophobicContact CE1-CG 3.75Å; F98-L311 HydrophobicContact CZ-CD2 4.11Å
99	Q	97.1	Very high	96.1	Very high	73 Å²	73	49.4 Å²	49.4	34%	0.341	23%	0.225	S	C	.	.	H	α-helix	trans	-64.2	-46.9	-176.2	-75.2	175.8	-57.2	0	0	112.8	R95 E96 G101 L205	R95-Q99 VanDerWaalsContact O-CG 3.3Å; R95-Q99 WeakPolarHBondContact O-CG 3.49Å; R95-Q99 PolarHBondContact O-N 2.87Å; E96-Q99 PolarHBondContact O-N 3.07Å; E96-Q99 VanDerWaalsContact O-N 3.14Å; Q99-G101 PolarHBondContact O-N 3.29Å; Q99-L205 HydrophobicContact CG-CD1 3.85Å; Q99-L205 HydrophobicContact CG-CD2 3.54Å; Q99-L205 HydrophobicContact CG-CG 4.34Å
100	N	96.3	Very high	95.9	Very high	65 Å²	65	45.5 Å²	45.5	35%	0.348	22%	0.217	S	C	.	.	T	Hydrogen-bonded Turn	trans	-78.3	2.4	177.9	61	29.2	0	0	0	113.7	E96 I97 H102	E96-N100 PolarHBondContact O-N 3.24Å; E96-N100 PolarHBondContact O-ND2 3.3Å; E96-N100 PolarHBondContact O-OD1 3.4Å; E96-N100 VanDerWaalsContact O-OD1 3.06Å; E96-N100 PolarHBondContact OE1-ND2 3.41Å; I97-N100 PolarHBondContact O-OD1 3.48Å; I97-N100 VanDerWaalsContact O-OD1 3.09Å; N100-H102 VanDerWaalsContact C-N 3.26Å; N100-H102 PolarHBondContact ND2-ND1 3.27Å; N100-H102 VanDerWaalsContact ND2-ND1 3.2Å; N100-H102 PolarHBondContact O-N 2.88Å; N100-H102 WeakPolarHBondContact OD1-CB 3.35Å; N100-H102 PolarHBondContact OD1-N 3.02Å; N100-H102 PolarHBondContact OD1-ND1 2.88Å
101	G	94.6	Very high	95.9	Very high	23 Å²	23	49.8 Å²	49.8	24%	0.237	24%	0.236	C	C	.	.	S	Bend	trans	77.2	1.4	177.5	0	0	0	0	0	115.1	F98 Q99 V103 R104	F98-G101 PolarHBondContact O-N 3.16Å; Q99-G101 PolarHBondContact O-N 3.29Å; G101-V103 PolarHBondContact O-N 2.99Å; G101-V103 VanDerWaalsContact O-N 3.11Å; G101-R104 VanDerWaalsContact O-CB 3.28Å; G101-R104 WeakPolarHBondContact O-CB 3.33Å; G101-R104 WeakPolarHBondContact O-CG 3.45Å; G101-R104 PolarHBondContact O-N 3.49Å
102	H	95.1	Very high	95.9	Very high	80 Å²	80	49.6 Å²	49.6	37%	0.37	24%	0.235	S	C	.	.	G	3₁₀ helix	trans	-60.1	-21.6	176.3	-70.8	148.9	0	0	0	113.3	I97 N100 R104 D105 N108	I97-H102 HydrophobicContact CG2-CB 4.17Å; I97-H102 PolarHBondContact O-N 3.39Å; N100-H102 VanDerWaalsContact C-N 3.26Å; N100-H102 PolarHBondContact ND2-ND1 3.27Å; N100-H102 VanDerWaalsContact ND2-ND1 3.2Å; N100-H102 PolarHBondContact O-N 2.88Å; N100-H102 WeakPolarHBondContact OD1-CB 3.35Å; N100-H102 PolarHBondContact OD1-N 3.02Å; N100-H102 PolarHBondContact OD1-ND1 2.88Å; H102-R104 PolarHBondContact O-N 3.19Å; H102-D105 PolarHBondContact O-N 3.08Å; H102-N108 PolarHBondContact O-ND2 2.92Å
103	V	94.3	Very high	95.9	Very high	2 Å²	2	48.3 Å²	48.3	1%	0.012	23%	0.227	C	C	.	.	G	3₁₀ helix	trans	-62	-20.5	171.7	74.4	0	0	0	0	113.5	I97 F98 G101 D105 M109	I97-V103 HydrophobicContact CG2-CB 4.16Å; I97-V103 PolarHBondContact O-N 3.47Å; F98-V103 HydrophobicContact CB-CG1 4.43Å; F98-V103 HydrophobicContact CD1-CB 4.23Å; F98-V103 HydrophobicContact CD1-CG1 3.94Å; F98-V103 HydrophobicContact CD1-CG2 3.98Å; F98-V103 HydrophobicContact CD2-CB 4.38Å; F98-V103 HydrophobicContact CD2-CG2 4.2Å; F98-V103 HydrophobicContact CE1-CB 4.48Å; F98-V103 HydrophobicContact CE1-CG1 4.44Å; F98-V103 HydrophobicContact CE1-CG2 3.73Å; F98-V103 HydrophobicContact CE2-CG2 3.98Å; F98-V103 HydrophobicContact CG-CB 4.18Å; F98-V103 HydrophobicContact CG-CG1 4.15Å; F98-V103 HydrophobicContact CG-CG2 4.21Å; F98-V103 HydrophobicContact CZ-CG2 3.73Å; G101-V103 PolarHBondContact O-N 2.99Å; G101-V103 VanDerWaalsContact O-N 3.11Å; V103-D105 VanDerWaalsContact C-N 3.29Å; V103-M109 HydrophobicContact CG2-SD 3.89Å
104	R	92.2	Very high	95.8	Very high	148 Å²	148	49.9 Å²	49.9	56%	0.558	24%	0.236	S	C	*	.	G	3₁₀ helix	trans	-68.5	-30.4	176	-65	-179.4	178.6	-133.9	3.4	112.1	G101 H102 E106	G101-R104 VanDerWaalsContact O-CB 3.28Å; G101-R104 WeakPolarHBondContact O-CB 3.33Å; G101-R104 WeakPolarHBondContact O-CG 3.45Å; G101-R104 PolarHBondContact O-N 3.49Å; H102-R104 PolarHBondContact O-N 3.19Å; R104-E106 PolarHBondContact O-N 2.84Å
105	D	92.1	Very high	95.8	Very high	9 Å²	9	52.9 Å²	52.9	5%	0.048	25%	0.247	C	C	.	.	S	Bend	trans	-78.7	106.6	169	179.5	-3.2	0	0	0	108.7	H102 V103 R107 N108	H102-D105 PolarHBondContact O-N 3.08Å; V103-D105 VanDerWaalsContact C-N 3.29Å; D105-R107 PolarHBondContact O-N 3.44Å; D105-R107 VanDerWaalsContact OD1-CB 3.28Å; D105-R107 WeakPolarHBondContact OD1-CB 3.31Å; D105-R107 VanDerWaalsContact OD1-CG 3.25Å; D105-R107 WeakPolarHBondContact OD1-CG 3.46Å; D105-R107 IonicContact OD1-CZ 3.94Å; D105-R107 PolarHBondContact OD1-N 3.02Å; D105-R107 VanDerWaalsContact OD1-N 3.09Å; D105-R107 IonicContact OD1-NE 2.91Å; D105-R107 PolarHBondContact OD1-NE 3.45Å; D105-R107 IonicContact OD1-NH2 2.71Å; D105-R107 IonicContact OD2-CZ 3.21Å; D105-R107 IonicContact OD2-NE 4Å; D105-R107 PolarHBondContact OD2-NE 3.23Å; D105-R107 IonicContact OD2-NH2 3.88Å; D105-R107 PolarHBondContact OD2-NH2 3.46Å; D105-N108 WeakPolarHBondContact O-CB 3.44Å; D105-N108 PolarHBondContact O-N 3.36Å
106	E	90.6	Very high	95.8	Very high	48 Å²	48	52.6 Å²	52.6	22%	0.224	25%	0.246	C	C	.	.	G	3₁₀ helix	trans	-61	-17.5	-174.1	-66.6	179.5	-178.1	0	0	113.2	R104 N108 M109 R304 A393	R104-E106 PolarHBondContact O-N 2.84Å; E106-N108 PolarHBondContact O-N 3.16Å; E106-M109 HydrophobicContact CB-CG 4.5Å; E106-M109 VanDerWaalsContact O-CB 3.26Å; E106-M109 WeakPolarHBondContact O-CB 3.41Å; E106-M109 WeakPolarHBondContact O-CG 3.34Å; E106-M109 PolarHBondContact O-N 2.82Å; E106-R304 IonicContact OE1-CZ 3.07Å; E106-R304 IonicContact OE1-NE 2.66Å; E106-R304 PolarHBondContact OE1-NE 2.71Å; E106-R304 IonicContact OE1-NH2 2.75Å; E106-R304 PolarHBondContact OE1-NH2 3.14Å; E106-R304 WeakPolarHBondContact OE2-CG 3.28Å; E106-R304 IonicContact OE2-NE 2.96Å; E106-R304 PolarHBondContact OE2-NE 2.94Å; E106-A393 HydrophobicContact CB-CB 4.37Å; E106-A393 WeakPolarHBondContact OE2-CA 3.43Å; E106-A393 WeakPolarHBondContact OE2-CB 3.47Å
107	R	90.9	Very high	95.9	Very high	142 Å²	142	52 Å²	52	54%	0.536	24%	0.243	S	C	.	.	G	3₁₀ helix	trans	-59.7	-27.4	172.1	-61.9	-179.3	-66.6	-178	-3.5	112.4	D105 M109 Y395	D105-R107 PolarHBondContact O-N 3.44Å; D105-R107 VanDerWaalsContact OD1-CB 3.28Å; D105-R107 WeakPolarHBondContact OD1-CB 3.31Å; D105-R107 VanDerWaalsContact OD1-CG 3.25Å; D105-R107 WeakPolarHBondContact OD1-CG 3.46Å; D105-R107 IonicContact OD1-CZ 3.94Å; D105-R107 PolarHBondContact OD1-N 3.02Å; D105-R107 VanDerWaalsContact OD1-N 3.09Å; D105-R107 IonicContact OD1-NE 2.91Å; D105-R107 PolarHBondContact OD1-NE 3.45Å; D105-R107 IonicContact OD1-NH2 2.71Å; D105-R107 IonicContact OD2-CZ 3.21Å; D105-R107 IonicContact OD2-NE 4Å; D105-R107 PolarHBondContact OD2-NE 3.23Å; D105-R107 IonicContact OD2-NH2 3.88Å; D105-R107 PolarHBondContact OD2-NH2 3.46Å; R107-M109 VanDerWaalsContact C-N 3.31Å; R107-Y395 VanDerWaalsContact CZ-CE2 3.46Å; R107-Y395 VanDerWaalsContact NH1-CE2 3.26Å
108	N	95.2	Very high	95.9	Very high	25 Å²	25	56.5 Å²	56.5	13%	0.134	26%	0.259	C	S	.	.	G	3₁₀ helix	trans	-78.9	-12.1	177	-70.6	-54.5	0	0	0	113.4	H102 D105 E106 L110 K111 V112	H102-N108 PolarHBondContact O-ND2 2.92Å; D105-N108 WeakPolarHBondContact O-CB 3.44Å; D105-N108 PolarHBondContact O-N 3.36Å; E106-N108 PolarHBondContact O-N 3.16Å; N108-L110 VanDerWaalsContact C-N 3.31Å; N108-L110 PolarHBondContact O-N 2.91Å; N108-K111 WeakPolarHBondContact O-CB 3.41Å; N108-K111 PolarHBondContact O-N 3.49Å; N108-K111 PolarHBondContact OD1-NZ 3.47Å; N108-V112 PolarHBondContact O-N 3.17Å
109	M	94.3	Very high	95.9	Very high	9 Å²	9	56 Å²	56	4%	0.044	26%	0.257	C	S	.	.	H	α-helix	trans	-62.3	-36.6	-177.2	-71.2	-59.4	-59.9	0	0	112.8	V103 E106 R107 K111 V112 M113 W209 V307 P308 L311	V103-M109 HydrophobicContact CG2-SD 3.89Å; E106-M109 HydrophobicContact CB-CG 4.5Å; E106-M109 VanDerWaalsContact O-CB 3.26Å; E106-M109 WeakPolarHBondContact O-CB 3.41Å; E106-M109 WeakPolarHBondContact O-CG 3.34Å; E106-M109 PolarHBondContact O-N 2.82Å; R107-M109 VanDerWaalsContact C-N 3.31Å; M109-K111 VanDerWaalsContact C-N 3.31Å; M109-K111 PolarHBondContact O-N 3.32Å; M109-V112 PolarHBondContact O-N 3.06Å; M109-M113 WeakPolarHBondContact O-CB 3.41Å; M109-M113 PolarHBondContact O-N 2.94Å; M109-W209 HydrophobicContact CE-CH2 4.44Å; M109-W209 HydrophobicContact CE-CZ2 3.81Å; M109-V307 HydrophobicContact CB-CB 4.31Å; M109-V307 HydrophobicContact CB-CG1 3.82Å; M109-P308 HydrophobicContact CE-CG 4.19Å; M109-L311 HydrophobicContact CE-CD2 3.95Å
110	L	95.7	Very high	96	Very high	107 Å²	107	52.6 Å²	52.6	56%	0.56	24%	0.241	S	C	*	.	H	α-helix	trans	-63.5	-38.9	175.5	180	62.3	0	0	0	111.5	N108 M113 T114	N108-L110 VanDerWaalsContact C-N 3.31Å; N108-L110 PolarHBondContact O-N 2.91Å; L110-M113 HydrophobicContact CD1-CE 3.91Å; L110-T114 VanDerWaalsContact O-CB 3.28Å; L110-T114 WeakPolarHBondContact O-CB 3.49Å; L110-T114 PolarHBondContact O-N 3.23Å; L110-T114 PolarHBondContact O-OG1 3.45Å
111	K	97.7	Very high	96.1	Very high	96 Å²	96	53 Å²	53	42%	0.417	25%	0.246	S	C	.	.	H	α-helix	trans	-66.2	-46.7	177.5	-175.8	-171.3	-64.5	158.1	0	110.7	I97 N108 M109 T114 R115	I97-K111 HydrophobicContact CD1-CD 4.03Å; N108-K111 WeakPolarHBondContact O-CB 3.41Å; N108-K111 PolarHBondContact O-N 3.49Å; N108-K111 PolarHBondContact OD1-NZ 3.47Å; M109-K111 VanDerWaalsContact C-N 3.31Å; M109-K111 PolarHBondContact O-N 3.32Å; K111-T114 PolarHBondContact O-N 3.49Å; K111-R115 WeakPolarHBondContact O-CG 3.34Å; K111-R115 PolarHBondContact O-N 3.16Å
112	V	98.3	Very high	96.3	Very high	0 Å²	0	52.4 Å²	52.4	0%	0	24%	0.237	C	C	.	.	H	α-helix	trans	-56.8	-54.2	175	169.8	0	0	0	0	110.3	V94 I97 F98 N108 M109 T114 R115 M116 L311	V94-V112 HydrophobicContact CG1-CG1 4.03Å; I97-V112 HydrophobicContact CB-CG2 4.42Å; I97-V112 HydrophobicContact CD1-CG2 4.2Å; I97-V112 HydrophobicContact CG2-CG2 3.73Å; F98-V112 HydrophobicContact CE2-CG1 3.78Å; F98-V112 HydrophobicContact CE2-CG2 4.26Å; F98-V112 HydrophobicContact CZ-CG1 4.29Å; N108-V112 PolarHBondContact O-N 3.17Å; M109-V112 PolarHBondContact O-N 3.06Å; V112-T114 PolarHBondContact O-N 3.19Å; V112-R115 PolarHBondContact O-N 3.06Å; V112-M116 HydrophobicContact CG1-CG 4.45Å; V112-M116 WeakPolarHBondContact O-CG 3.49Å; V112-M116 PolarHBondContact O-N 2.91Å; V112-L311 HydrophobicContact CG1-CD1 4.01Å; V112-L311 HydrophobicContact CG1-CD2 4.05Å
113	M	98.1	Very high	96.5	Very high	28 Å²	28	48.6 Å²	48.6	14%	0.138	22%	0.22	C	C	.	.	H	α-helix	trans	-57.7	-47.9	179.4	-173.8	-71.5	-68	0	0	111.3	M109 L110 R115 M116 H117 V307 Q310	M109-M113 WeakPolarHBondContact O-CB 3.41Å; M109-M113 PolarHBondContact O-N 2.94Å; L110-M113 HydrophobicContact CD1-CE 3.91Å; M113-R115 VanDerWaalsContact C-N 3.3Å; M113-R115 PolarHBondContact O-N 2.76Å; M113-M116 PolarHBondContact O-N 3.49Å; M113-H117 WeakPolarHBondContact O-CB 3.25Å; M113-H117 PolarHBondContact O-N 3.24Å; M113-H117 HydrophobicContact SD-CB 4.08Å; M113-V307 HydrophobicContact CB-CG1 3.78Å; M113-V307 HydrophobicContact CG-CG1 4.21Å; M113-Q310 HydrophobicContact CG-CB 3.9Å
114	T	98.4	Very high	96.7	Very high	59 Å²	59	53.2 Å²	53.2	36%	0.362	24%	0.24	S	C	.	.	H	α-helix	trans	-58.6	-40.8	-179.7	-58.4	0	0	0	0	112.2	L110 K111 V112 R118	L110-T114 VanDerWaalsContact O-CB 3.28Å; L110-T114 WeakPolarHBondContact O-CB 3.49Å; L110-T114 PolarHBondContact O-N 3.23Å; L110-T114 PolarHBondContact O-OG1 3.45Å; K111-T114 PolarHBondContact O-N 3.49Å; V112-T114 PolarHBondContact O-N 3.19Å; T114-R118 WeakPolarHBondContact O-CB 3.46Å; T114-R118 PolarHBondContact O-N 3.26Å
115	R	98.8	Very high	97	Very high	65 Å²	65	49.7 Å²	49.7	25%	0.245	23%	0.231	C	C	.	.	H	α-helix	trans	-70.2	-42.7	177.7	-68.5	-174.4	178.8	166.2	-1.4	112	E90 S93 V94 K111 V112 M113 H117 R118 V119	E90-R115 WeakPolarHBondContact OE2-CD 3.3Å; E90-R115 VanDerWaalsContact OE2-CG 3.23Å; E90-R115 WeakPolarHBondContact OE2-CG 3.29Å; E90-R115 IonicContact OE2-NE 3.97Å; S93-R115 VanDerWaalsContact OG-CD 3.27Å; S93-R115 WeakPolarHBondContact OG-CD 3.45Å; S93-R115 PolarHBondContact OG-NH1 2.85Å; V94-R115 HydrophobicContact CG2-CB 3.75Å; K111-R115 WeakPolarHBondContact O-CG 3.34Å; K111-R115 PolarHBondContact O-N 3.16Å; V112-R115 PolarHBondContact O-N 3.06Å; M113-R115 VanDerWaalsContact C-N 3.3Å; M113-R115 PolarHBondContact O-N 2.76Å; R115-H117 VanDerWaalsContact C-N 3.34Å; R115-H117 PolarHBondContact O-N 3.22Å; R115-R118 WeakPolarHBondContact O-CB 3.18Å; R115-R118 PolarHBondContact O-N 3.33Å; R115-R118 VanDerWaalsContact O-N 3.16Å; R115-V119 PolarHBondContact O-N 3.07Å
116	M	98.6	Very high	97.3	Very high	1 Å²	1	49.2 Å²	49.2	1%	0.005	23%	0.229	C	C	.	.	H	α-helix	trans	-64.9	-39.1	175.8	-64.7	-49.5	-67.5	0	0	111.9	V94 V112 M113 R118 V119 V120 L202 L311 L315 I318	V94-M116 HydrophobicContact CB-SD 4.16Å; V94-M116 HydrophobicContact CG1-CG 4.39Å; V94-M116 HydrophobicContact CG1-SD 3.94Å; V94-M116 HydrophobicContact CG2-CG 4.38Å; V94-M116 HydrophobicContact CG2-SD 3.93Å; V112-M116 HydrophobicContact CG1-CG 4.45Å; V112-M116 WeakPolarHBondContact O-CG 3.49Å; V112-M116 PolarHBondContact O-N 2.91Å; M113-M116 PolarHBondContact O-N 3.49Å; M116-R118 VanDerWaalsContact C-N 3.34Å; M116-R118 PolarHBondContact O-N 3.23Å; M116-V119 WeakPolarHBondContact O-CB 3.46Å; M116-V119 PolarHBondContact O-N 2.91Å; M116-V120 PolarHBondContact O-N 3.27Å; M116-L202 HydrophobicContact CE-CD2 3.57Å; M116-L311 HydrophobicContact CB-CD1 4.14Å; M116-L311 HydrophobicContact CG-CD1 3.73Å; M116-L315 HydrophobicContact CE-CD2 3.73Å; M116-I318 HydrophobicContact CE-CD1 3.34Å
117	H	98.6	Very high	97.7	Very high	85 Å²	85	48 Å²	48	39%	0.394	23%	0.225	S	C	.	.	H	α-helix	trans	-65.1	-36.8	172.6	-171.8	72.2	0	0	0	112.1	M113 R115 V119 V120 V121	M113-H117 WeakPolarHBondContact O-CB 3.25Å; M113-H117 PolarHBondContact O-N 3.24Å; M113-H117 HydrophobicContact SD-CB 4.08Å; R115-H117 VanDerWaalsContact C-N 3.34Å; R115-H117 PolarHBondContact O-N 3.22Å; H117-V119 VanDerWaalsContact C-N 3.32Å; H117-V119 PolarHBondContact O-N 2.98Å; H117-V120 VanDerWaalsContact O-CB 3.31Å; H117-V120 WeakPolarHBondContact O-CB 3.31Å; H117-V120 PolarHBondContact O-N 3.09Å; H117-V120 VanDerWaalsContact O-N 3.17Å; H117-V121 WeakPolarHBondContact O-CG2 3.41Å; H117-V121 PolarHBondContact O-N 3.36Å
118	R	98.8	Very high	98	Very high	108 Å²	108	47.3 Å²	47.3	41%	0.408	23%	0.228	S	C	.	.	H	α-helix	trans	-60.1	-42.6	172.2	-174.9	-177.1	-63.1	147.3	3.8	111.5	E90 T114 R115 M116 V120 V121 I122	E90-R118 VanDerWaalsContact OE1-CD 3.25Å; E90-R118 WeakPolarHBondContact OE1-CD 3.44Å; E90-R118 IonicContact OE1-CZ 3.69Å; E90-R118 IonicContact OE1-NE 3.58Å; E90-R118 IonicContact OE1-NH1 2.74Å; E90-R118 PolarHBondContact OE1-NH1 3.47Å; E90-R118 IonicContact OE2-NH1 3.13Å; E90-R118 PolarHBondContact OE2-NH1 3.12Å; E90-R118 VanDerWaalsContact OE2-NH1 3.13Å; T114-R118 WeakPolarHBondContact O-CB 3.46Å; T114-R118 PolarHBondContact O-N 3.26Å; R115-R118 WeakPolarHBondContact O-CB 3.18Å; R115-R118 PolarHBondContact O-N 3.33Å; R115-R118 VanDerWaalsContact O-N 3.16Å; M116-R118 VanDerWaalsContact C-N 3.34Å; M116-R118 PolarHBondContact O-N 3.23Å; R118-V120 VanDerWaalsContact C-N 3.33Å; R118-V120 PolarHBondContact O-N 3.12Å; R118-V121 PolarHBondContact O-N 3.12Å; R118-V121 VanDerWaalsContact O-N 3.16Å; R118-I122 HydrophobicContact CG-CD1 4.1Å; R118-I122 WeakPolarHBondContact O-CG1 3.39Å; R118-I122 PolarHBondContact O-N 3.43Å
119	V	98.8	Very high	98.2	Very high	4 Å²	4	47.3 Å²	47.3	2%	0.024	23%	0.227	C	C	.	.	H	α-helix	trans	-58.8	-44.2	173.5	173.3	0	0	0	0	111	I87 E90 R115 M116 H117 V121 I122 F123 I318	I87-V119 HydrophobicContact CG1-CG1 4.39Å; I87-V119 HydrophobicContact CG2-CG1 3.75Å; I87-V119 HydrophobicContact CG2-CG2 4.18Å; E90-V119 HydrophobicContact CB-CG2 3.67Å; E90-V119 HydrophobicContact CG-CG2 4.24Å; R115-V119 PolarHBondContact O-N 3.07Å; M116-V119 WeakPolarHBondContact O-CB 3.46Å; M116-V119 PolarHBondContact O-N 2.91Å; H117-V119 VanDerWaalsContact C-N 3.32Å; H117-V119 PolarHBondContact O-N 2.98Å; V119-V121 VanDerWaalsContact C-N 3.34Å; V119-V121 PolarHBondContact O-N 3.09Å; V119-I122 PolarHBondContact O-N 3.22Å; V119-F123 HydrophobicContact CG1-CD2 3.62Å; V119-F123 HydrophobicContact CG1-CE2 3.55Å; V119-F123 VanDerWaalsContact O-CD2 3.31Å; V119-F123 WeakPolarHBondContact O-CD2 3.3Å; V119-F123 PolarHBondContact O-N 3.46Å; V119-I318 HydrophobicContact CB-CD1 4.17Å; V119-I318 HydrophobicContact CG1-CD1 3.78Å; V119-I318 HydrophobicContact CG1-CG1 4.02Å
120	V	98.8	Very high	98.3	Very high	0 Å²	0	47.1 Å²	47.1	0%	0	23%	0.226	C	C	.	.	H	α-helix	trans	-56	-46.5	173.1	170.4	0	0	0	0	111.5	M116 H117 R118 F123 K124 D317 I318 L321	M116-V120 PolarHBondContact O-N 3.27Å; H117-V120 VanDerWaalsContact O-CB 3.31Å; H117-V120 WeakPolarHBondContact O-CB 3.31Å; H117-V120 PolarHBondContact O-N 3.09Å; H117-V120 VanDerWaalsContact O-N 3.17Å; R118-V120 VanDerWaalsContact C-N 3.33Å; R118-V120 PolarHBondContact O-N 3.12Å; V120-F123 PolarHBondContact O-N 2.56Å; V120-K124 WeakPolarHBondContact O-CG 3.48Å; V120-K124 PolarHBondContact O-N 3.31Å; V120-D317 HydrophobicContact CG1-CB 3.98Å; V120-D317 HydrophobicContact CG2-CB 3.71Å; V120-I318 HydrophobicContact CG2-CD1 4.34Å; V120-I318 HydrophobicContact CG2-CG1 3.66Å; V120-L321 HydrophobicContact CB-CD1 4.37Å; V120-L321 HydrophobicContact CG1-CD1 3.74Å; V120-L321 WeakPolarHBondContact O-CD1 3.33Å
121	V	98.9	Very high	98.4	Very high	74 Å²	74	45.4 Å²	45.4	45%	0.448	22%	0.223	S	C	.	.	H	α-helix	trans	-64.6	-43	179.6	174.1	0	0	0	0	111.6	H117 R118 V119 F123 K124 L125	H117-V121 WeakPolarHBondContact O-CG2 3.41Å; H117-V121 PolarHBondContact O-N 3.36Å; R118-V121 PolarHBondContact O-N 3.12Å; R118-V121 VanDerWaalsContact O-N 3.16Å; V119-V121 VanDerWaalsContact C-N 3.34Å; V119-V121 PolarHBondContact O-N 3.09Å; V121-F123 PolarHBondContact O-N 3.11Å; V121-K124 WeakPolarHBondContact O-CB 3.3Å; V121-K124 PolarHBondContact O-N 3.3Å; V121-L125 PolarHBondContact O-N 2.9Å
122	I	98.8	Very high	98.4	Very high	10 Å²	10	44.3 Å²	44.3	5%	0.051	22%	0.224	C	C	.	.	H	α-helix	trans	-61.3	-46.3	176.4	-64.2	164.8	0	0	0	109.9	W83 Q86 I87 R118 V119 K124 L125 L126	W83-I122 HydrophobicContact CB-CG2 3.88Å; W83-I122 HydrophobicContact CD2-CG2 3.89Å; W83-I122 HydrophobicContact CE3-CB 4.39Å; W83-I122 HydrophobicContact CE3-CD1 4.12Å; W83-I122 HydrophobicContact CE3-CG1 3.92Å; W83-I122 HydrophobicContact CE3-CG2 3.56Å; W83-I122 HydrophobicContact CG-CG2 4.05Å; W83-I122 HydrophobicContact CZ3-CD1 4.22Å; W83-I122 HydrophobicContact CZ3-CG1 3.95Å; W83-I122 HydrophobicContact CZ3-CG2 4.38Å; Q86-I122 HydrophobicContact CB-CD1 4.31Å; Q86-I122 HydrophobicContact CG-CD1 3.7Å; I87-I122 HydrophobicContact CD1-CB 4.39Å; I87-I122 HydrophobicContact CD1-CG2 3.74Å; I87-I122 HydrophobicContact CG1-CB 4.19Å; I87-I122 HydrophobicContact CG1-CD1 4.22Å; I87-I122 HydrophobicContact CG1-CG2 3.8Å; R118-I122 HydrophobicContact CG-CD1 4.1Å; R118-I122 WeakPolarHBondContact O-CG1 3.39Å; R118-I122 PolarHBondContact O-N 3.43Å; V119-I122 PolarHBondContact O-N 3.22Å; I122-K124 VanDerWaalsContact C-N 3.3Å; I122-K124 PolarHBondContact O-N 3.22Å; I122-L125 WeakPolarHBondContact O-CA 3.35Å; I122-L125 WeakPolarHBondContact O-CB 3.37Å; I122-L125 PolarHBondContact O-N 3.41Å; I122-L126 HydrophobicContact CG2-CD1 4.41Å; I122-L126 HydrophobicContact CG2-CG 4.27Å; I122-L126 WeakPolarHBondContact O-CG 3.28Å; I122-L126 PolarHBondContact O-N 3.27Å
123	F	98.6	Very high	98.3	Very high	1 Å²	1	44.4 Å²	44.4	0%	0.004	22%	0.224	C	C	.	.	H	α-helix	trans	-61.8	-34.9	177.5	-87.5	-63.9	0	0	0	113.6	I87 V119 V120 V121 L125 L126 V127 L162 I318 L321 M322	I87-F123 HydrophobicContact CD1-CD1 4.37Å; I87-F123 HydrophobicContact CD1-CD2 4.22Å; I87-F123 HydrophobicContact CD1-CE1 4.15Å; I87-F123 HydrophobicContact CD1-CE2 4Å; I87-F123 HydrophobicContact CD1-CG 4.41Å; I87-F123 HydrophobicContact CD1-CZ 3.98Å; I87-F123 HydrophobicContact CG2-CE2 4.28Å; V119-F123 HydrophobicContact CG1-CD2 3.62Å; V119-F123 HydrophobicContact CG1-CE2 3.55Å; V119-F123 VanDerWaalsContact O-CD2 3.31Å; V119-F123 WeakPolarHBondContact O-CD2 3.3Å; V119-F123 PolarHBondContact O-N 3.46Å; V120-F123 PolarHBondContact O-N 2.56Å; V121-F123 PolarHBondContact O-N 3.11Å; F123-L125 VanDerWaalsContact C-N 3.3Å; F123-L125 PolarHBondContact O-N 2.93Å; F123-L126 HydrophobicContact CD1-CD1 4.23Å; F123-L126 PolarHBondContact O-N 3.44Å; F123-V127 VanDerWaalsContact O-CG2 3.31Å; F123-V127 WeakPolarHBondContact O-CG2 3.37Å; F123-V127 PolarHBondContact O-N 3.11Å; F123-L162 HydrophobicContact CE1-CD2 4.37Å; F123-L162 HydrophobicContact CZ-CD2 3.83Å; F123-I318 HydrophobicContact CD2-CG2 4.44Å; F123-I318 HydrophobicContact CE2-CG2 3.98Å; F123-L321 HydrophobicContact CB-CB 3.76Å; F123-L321 HydrophobicContact CB-CD1 3.88Å; F123-L321 HydrophobicContact CB-CG 4.37Å; F123-L321 HydrophobicContact CG-CB 4.36Å; F123-M322 HydrophobicContact CE1-CG 3.79Å; F123-M322 HydrophobicContact CE1-SD 3.4Å; F123-M322 WeakPolarHBondContact CE1-SD 3.36Å; F123-M322 HydrophobicContact CE2-CG 4.17Å; F123-M322 HydrophobicContact CE2-SD 4.43Å; F123-M322 HydrophobicContact CZ-CG 3.56Å; F123-M322 HydrophobicContact CZ-SD 3.33Å; F123-M322 WeakPolarHBondContact CZ-SD 3.36Å
124	K	98.7	Very high	98.3	Very high	99 Å²	99	46.5 Å²	46.5	43%	0.43	23%	0.234	S	C	.	.	H	α-helix	trans	-59.5	-43.2	172.5	-73.3	173.6	-178.8	175.2	0	111.2	V120 V121 I122 V127 Q128 L321	V120-K124 WeakPolarHBondContact O-CG 3.48Å; V120-K124 PolarHBondContact O-N 3.31Å; V121-K124 WeakPolarHBondContact O-CB 3.3Å; V121-K124 PolarHBondContact O-N 3.3Å; I122-K124 VanDerWaalsContact C-N 3.3Å; I122-K124 PolarHBondContact O-N 3.22Å; K124-V127 PolarHBondContact O-N 3.18Å; K124-Q128 WeakPolarHBondContact O-CG 3.5Å; K124-Q128 PolarHBondContact O-N 3.24Å; K124-L321 HydrophobicContact CG-CD1 3.85Å; K124-L321 HydrophobicContact CG-CD2 3.79Å
125	L	98.7	Very high	98.3	Very high	73 Å²	73	48.5 Å²	48.5	38%	0.382	25%	0.246	S	C	.	.	H	α-helix	trans	-63.2	-44.9	174.7	-178.4	66.7	0	0	0	111.3	W83 V121 I122 F123 V127 Q128 Q129	W83-L125 HydrophobicContact CH2-CD2 4.36Å; W83-L125 HydrophobicContact CZ2-CD2 3.55Å; V121-L125 PolarHBondContact O-N 2.9Å; I122-L125 WeakPolarHBondContact O-CA 3.35Å; I122-L125 WeakPolarHBondContact O-CB 3.37Å; I122-L125 PolarHBondContact O-N 3.41Å; F123-L125 VanDerWaalsContact C-N 3.3Å; F123-L125 PolarHBondContact O-N 2.93Å; L125-V127 VanDerWaalsContact C-N 3.3Å; L125-V127 PolarHBondContact O-N 3.26Å; L125-Q128 PolarHBondContact O-N 2.96Å; L125-Q128 VanDerWaalsContact O-N 3.09Å; L125-Q129 WeakPolarHBondContact O-CB 3.33Å; L125-Q129 PolarHBondContact O-N 3.01Å
126	L	98.5	Very high	98.2	Very high	0 Å²	0	45.6 Å²	45.6	0%	0	24%	0.235	C	C	.	.	H	α-helix	trans	-61.3	-36.7	177.9	-66.2	-168.8	0	0	0	113	Y80 W83 F84 I87 I122 F123 Q128 Q129	Y80-L126 HydrophobicContact CD1-CB 4.3Å; Y80-L126 HydrophobicContact CD1-CD1 4.31Å; Y80-L126 HydrophobicContact CD1-CD2 3.52Å; Y80-L126 HydrophobicContact CD1-CG 4.24Å; Y80-L126 HydrophobicContact CE1-CB 3.89Å; Y80-L126 HydrophobicContact CE1-CD2 3.78Å; Y80-L126 HydrophobicContact CE1-CG 4.3Å; Y80-L126 WeakPolarHBondContact CE1-O 3Å; Y80-L126 PolarHBondContact OH-O 2.91Å; Y80-L126 VanDerWaalsContact OH-O 3.05Å; W83-L126 HydrophobicContact CB-CD1 4.23Å; W83-L126 HydrophobicContact CB-CD2 3.61Å; W83-L126 HydrophobicContact CB-CG 4.29Å; W83-L126 HydrophobicContact CG-CD2 3.75Å; F84-L126 HydrophobicContact CD1-CD1 3.98Å; F84-L126 HydrophobicContact CE1-CD1 3.67Å; I87-L126 HydrophobicContact CD1-CD1 3.97Å; I122-L126 HydrophobicContact CG2-CD1 4.41Å; I122-L126 HydrophobicContact CG2-CG 4.27Å; I122-L126 WeakPolarHBondContact O-CG 3.28Å; I122-L126 PolarHBondContact O-N 3.27Å; F123-L126 HydrophobicContact CD1-CD1 4.23Å; F123-L126 PolarHBondContact O-N 3.44Å; L126-Q128 VanDerWaalsContact C-N 3.34Å; L126-Q129 PolarHBondContact O-N 3.21Å
127	V	98.3	Very high	98.2	Very high	22 Å²	22	48.4 Å²	48.4	13%	0.133	25%	0.252	C	S	.	.	H	α-helix	trans	-65.7	-39.2	174.8	169.6	0	0	0	0	111.2	F123 K124 L125 L321 K324 W325 N328	F123-V127 VanDerWaalsContact O-CG2 3.31Å; F123-V127 WeakPolarHBondContact O-CG2 3.37Å; F123-V127 PolarHBondContact O-N 3.11Å; K124-V127 PolarHBondContact O-N 3.18Å; L125-V127 VanDerWaalsContact C-N 3.3Å; L125-V127 PolarHBondContact O-N 3.26Å; V127-L321 HydrophobicContact CG2-CD2 4.37Å; V127-K324 HydrophobicContact CG1-CB 4.46Å; V127-K324 HydrophobicContact CG2-CB 4.13Å; V127-W325 HydrophobicContact CG2-CB 4.03Å; V127-N328 WeakPolarHBondContact CG1-ND2 3.34Å; V127-N328 PolarHBondContact O-ND2 3.44Å
128	Q	97.9	Very high	98.1	Very high	128 Å²	128	46 Å²	46	60%	0.598	25%	0.248	S	C	*	.	H	α-helix	trans	-72.3	-34.7	177.8	-70.3	173.9	-3.4	0	0	112.3	K124 L125 L126 F130 S131	K124-Q128 WeakPolarHBondContact O-CG 3.5Å; K124-Q128 PolarHBondContact O-N 3.24Å; L125-Q128 PolarHBondContact O-N 2.96Å; L125-Q128 VanDerWaalsContact O-N 3.09Å; L126-Q128 VanDerWaalsContact C-N 3.34Å; Q128-F130 PolarHBondContact O-N 3.19Å; Q128-S131 WeakPolarHBondContact O-CB 3.39Å; Q128-S131 PolarHBondContact O-N 3.32Å; Q128-S131 PolarHBondContact O-OG 2.94Å
129	Q	98	Very high	98	Very high	25 Å²	25	47.3 Å²	47.3	12%	0.117	26%	0.262	C	S	.	.	H	α-helix	trans	-58	-23.4	-176.1	-174.2	173.9	-33.6	0	0	113.6	T76 Y80 L125 L126 S131 V132	T76-Q129 PolarHBondContact O-NE2 3.27Å; T76-Q129 VanDerWaalsContact O-NE2 3.16Å; Y80-Q129 HydrophobicContact CE1-CB 4.3Å; Y80-Q129 HydrophobicContact CE1-CG 4.48Å; Y80-Q129 HydrophobicContact CE2-CG 4.23Å; L125-Q129 WeakPolarHBondContact O-CB 3.33Å; L125-Q129 PolarHBondContact O-N 3.01Å; L126-Q129 PolarHBondContact O-N 3.21Å; Q129-S131 PolarHBondContact O-N 3.26Å; Q129-V132 WeakPolarHBondContact O-CB 3.37Å; Q129-V132 PolarHBondContact O-N 2.96Å; Q129-V132 VanDerWaalsContact O-N 3.12Å
130	F	96.9	Very high	97.9	Very high	5 Å²	5	50.1 Å²	50.1	2%	0.022	28%	0.277	C	S	.	.	H	α-helix	trans	-53.8	-35.6	170.1	-79.1	-67.8	0	0	0	112.9	Y80 Q128 V132 L133 E134 W325 N328 H329 M332	Y80-F130 WeakPolarHBondContact OH-CD2 3.29Å; Y80-F130 WeakPolarHBondContact OH-CG 3.26Å; Y80-F130 PolarHBondContact OH-N 3.08Å; Q128-F130 PolarHBondContact O-N 3.19Å; F130-V132 PolarHBondContact O-N 2.88Å; F130-V132 VanDerWaalsContact O-N 3.09Å; F130-L133 PolarHBondContact O-N 3.29Å; F130-L133 VanDerWaalsContact O-N 3.11Å; F130-E134 WeakPolarHBondContact O-CB 3.48Å; F130-E134 VanDerWaalsContact O-CG 3.23Å; F130-E134 WeakPolarHBondContact O-CG 3.44Å; F130-E134 PolarHBondContact O-N 3.14Å; F130-W325 AromaticContact CE2-CD1 3.46Å; F130-W325 VanDerWaalsContact CE2-CD1 3.46Å; F130-W325 HydrophobicContact CE2-CD2 4.28Å; F130-W325 AromaticContact CE2-CG 3.94Å; F130-W325 HydrophobicContact CE2-CG 3.94Å; F130-W325 AromaticContact CE2-NE1 3.49Å; F130-W325 WeakPolarHBondContact CE2-O 3.28Å; F130-W325 HydrophobicContact CZ-CD2 4.32Å; F130-W325 AromaticContact CZ-CE2 3.79Å; F130-W325 HydrophobicContact CZ-CG 4.45Å; F130-W325 HydrophobicContact CZ-CZ2 4.18Å; F130-W325 AromaticContact CZ-NE1 3.6Å; F130-N328 HydrophobicContact CB-CB 4.5Å; F130-N328 HydrophobicContact CD2-CB 3.51Å; F130-N328 HydrophobicContact CE2-CB 3.91Å; F130-N328 HydrophobicContact CG-CB 4.07Å; F130-H329 HydrophobicContact CE1-CB 3.94Å; F130-H329 HydrophobicContact CE2-CB 4.37Å; F130-H329 HydrophobicContact CZ-CB 3.58Å; F130-M332 HydrophobicContact CD1-CE 4.31Å; F130-M332 HydrophobicContact CD1-SD 3.74Å; F130-M332 HydrophobicContact CE1-CE 4.11Å; F130-M332 HydrophobicContact CE1-SD 4.15Å
131	S	97.4	Very high	97.8	Very high	71 Å²	71	51.1 Å²	51.1	50%	0.497	28%	0.281	S	S	.	.	H	α-helix	trans	-60.2	-25.6	-179.2	72.6	0	0	0	0	113.1	Q128 Q129	Q128-S131 WeakPolarHBondContact O-CB 3.39Å; Q128-S131 PolarHBondContact O-N 3.32Å; Q128-S131 PolarHBondContact O-OG 2.94Å; Q129-S131 PolarHBondContact O-N 3.26Å
132	V	97.8	Very high	97.6	Very high	72 Å²	72	51.3 Å²	51.3	44%	0.436	28%	0.28	S	S	.	.	H	α-helix	trans	-73.3	-49.6	176.5	-174.4	0	0	0	0	110.1	L72 Q129 F130 E134 T135	L72-V132 HydrophobicContact CD1-CG1 3.99Å; Q129-V132 WeakPolarHBondContact O-CB 3.37Å; Q129-V132 PolarHBondContact O-N 2.96Å; Q129-V132 VanDerWaalsContact O-N 3.12Å; F130-V132 PolarHBondContact O-N 2.88Å; F130-V132 VanDerWaalsContact O-N 3.09Å; V132-E134 PolarHBondContact O-N 3.41Å; V132-T135 WeakPolarHBondContact O-CG2 3.47Å; V132-T135 PolarHBondContact O-N 3.06Å; V132-T135 PolarHBondContact O-OG1 3.41Å
133	L	97.4	Very high	97.5	Very high	3 Å²	3	54.7 Å²	54.7	2%	0.016	30%	0.298	C	S	.	.	H	α-helix	trans	-68.7	-23.4	177.1	-169.3	58	0	0	0	112	L72 F73 T76 F130 T135 M136 M332	L72-L133 HydrophobicContact CG-CD1 4.27Å; F73-L133 HydrophobicContact CD2-CD1 4.4Å; T76-L133 HydrophobicContact CG2-CB 4.04Å; T76-L133 HydrophobicContact CG2-CD2 4.08Å; T76-L133 HydrophobicContact CG2-CG 4.48Å; F130-L133 PolarHBondContact O-N 3.29Å; F130-L133 VanDerWaalsContact O-N 3.11Å; L133-T135 PolarHBondContact O-N 2.82Å; L133-M136 HydrophobicContact CD1-CE 3.77Å; L133-M136 HydrophobicContact CG-CE 4.3Å; L133-M136 WeakPolarHBondContact O-CB 3.36Å; L133-M136 PolarHBondContact O-N 2.83Å; L133-M332 HydrophobicContact CB-SD 4.25Å; L133-M332 HydrophobicContact CD2-CE 4.12Å; L133-M332 HydrophobicContact CD2-SD 3.62Å; L133-M332 HydrophobicContact CG-SD 3.98Å
134	E	97.1	Very high	97.4	Very high	71 Å²	71	54.6 Å²	54.6	33%	0.332	30%	0.298	S	S	.	.	T	Hydrogen-bonded Turn	trans	-68.7	-13.5	176.6	-76.5	-176.5	151.3	0	0	113.9	F130 V132 M136 M332 R335	F130-E134 WeakPolarHBondContact O-CB 3.48Å; F130-E134 VanDerWaalsContact O-CG 3.23Å; F130-E134 WeakPolarHBondContact O-CG 3.44Å; F130-E134 PolarHBondContact O-N 3.14Å; V132-E134 PolarHBondContact O-N 3.41Å; E134-M136 PolarHBondContact O-N 2.7Å; E134-M332 HydrophobicContact CG-CB 4.42Å; E134-M332 HydrophobicContact CG-CG 4.14Å; E134-R335 VanDerWaalsContact C-NH2 3.33Å; E134-R335 VanDerWaalsContact CG-NH2 3.27Å; E134-R335 PolarHBondContact O-NH1 2.75Å; E134-R335 VanDerWaalsContact O-NH1 3.15Å; E134-R335 PolarHBondContact O-NH2 3.5Å
135	T	98.1	Very high	97.2	Very high	102 Å²	102	52.4 Å²	52.4	63%	0.626	29%	0.287	S	S	*	.	T	Hydrogen-bonded Turn	trans	-71.2	-21.5	172.9	69.2	0	0	0	0	112.8	V132 L133	V132-T135 WeakPolarHBondContact O-CG2 3.47Å; V132-T135 PolarHBondContact O-N 3.06Å; V132-T135 PolarHBondContact O-OG1 3.41Å; L133-T135 PolarHBondContact O-N 2.82Å
136	M	98.2	Very high	96.9	Very high	3 Å²	3	55.2 Å²	55.2	2%	0.015	30%	0.298	C	S	.	.	S	Bend	trans	-68.3	136.9	171.2	177.6	172.6	66.6	0	0	109.8	D69 L72 F73 L133 E134 F141 F144 R335 M336	D69-M136 HydrophobicContact CB-CG 4.04Å; D69-M136 HydrophobicContact CB-SD 3.88Å; D69-M136 VanDerWaalsContact OD2-CG 3.3Å; D69-M136 WeakPolarHBondContact OD2-CG 3.22Å; L72-M136 HydrophobicContact CD2-CB 4.37Å; F73-M136 HydrophobicContact CD2-CE 4.27Å; L133-M136 HydrophobicContact CD1-CE 3.77Å; L133-M136 HydrophobicContact CG-CE 4.3Å; L133-M136 WeakPolarHBondContact O-CB 3.36Å; L133-M136 PolarHBondContact O-N 2.83Å; E134-M136 PolarHBondContact O-N 2.7Å; M136-F141 HydrophobicContact CE-CB 3.94Å; M136-F141 HydrophobicContact CE-CD2 3.59Å; M136-F141 HydrophobicContact CE-CE2 4.48Å; M136-F141 HydrophobicContact CE-CG 4.04Å; M136-F141 HydrophobicContact CG-CB 4.26Å; M136-F141 HydrophobicContact SD-CB 4Å; M136-F141 HydrophobicContact SD-CD2 4.14Å; M136-F144 HydrophobicContact CE-CZ 4.29Å; M136-F144 HydrophobicContact SD-CE1 3.61Å; M136-F144 HydrophobicContact SD-CZ 3.61Å; M136-R335 PolarHBondContact O-NH1 3.28Å; M136-M336 HydrophobicContact CB-CE 4.21Å; M136-M336 HydrophobicContact CE-CE 3.81Å; M136-M336 HydrophobicContact CE-SD 4.31Å; M136-M336 HydrophobicContact CG-CE 4.4Å; M136-M336 VanDerWaalsContact O-CE 3.27Å; M136-M336 WeakPolarHBondContact O-CE 3.1Å
137	T	97.6	Very high	96.7	Very high	60 Å²	60	57.4 Å²	57.4	37%	0.368	31%	0.306	S	S	.	.			trans	-84.8	156.9	176	84.3	0	0	0	0	111.1	L139 D140 F141	T137-L139 PolarHBondContact O-N 3.22Å; T137-L139 PolarHBondContact OG1-N 2.75Å; T137-D140 WeakPolarHBondContact CB-OD2 3.36Å; T137-D140 WeakPolarHBondContact CG2-OD2 3.42Å; T137-D140 PolarHBondContact O-N 2.99Å; T137-D140 VanDerWaalsContact OG1-CG 3.26Å; T137-D140 PolarHBondContact OG1-N 3.02Å; T137-D140 VanDerWaalsContact OG1-N 3.14Å; T137-D140 PolarHBondContact OG1-OD2 2.86Å; T137-F141 WeakPolarHBondContact O-CB 3.27Å; T137-F141 PolarHBondContact O-N 3.07Å
138	A	96.6	Very high	96.4	Very high	36 Å²	36	57.9 Å²	57.9	30%	0.298	31%	0.308	S	S	.	.	H	α-helix	trans	-65.7	-23.1	175.4	0	0	0	0	0	112.7	N142 R335 M336	A138-N142 WeakPolarHBondContact O-CB 3.32Å; A138-N142 PolarHBondContact O-N 3.46Å; A138-R335 WeakPolarHBondContact CB-O 3.26Å; A138-M336 HydrophobicContact CB-SD 4.39Å
139	L	96	Very high	95.7	Very high	135 Å²	135	55.5 Å²	55.5	71%	0.707	31%	0.306	S	S	*	.	H	α-helix	trans	-72.5	-52.4	175.4	-67.8	172.5	0	0	0	110	T137 F141 N142 D143	T137-L139 PolarHBondContact O-N 3.22Å; T137-L139 PolarHBondContact OG1-N 2.75Å; L139-F141 VanDerWaalsContact C-N 3.27Å; L139-F141 PolarHBondContact O-N 3.24Å; L139-N142 WeakPolarHBondContact O-CA 3.26Å; L139-N142 WeakPolarHBondContact O-CB 3.33Å; L139-N142 PolarHBondContact O-N 3.19Å; L139-D143 PolarHBondContact O-N 2.97Å
140	D	97	Very high	95	Very high	63 Å²	63	59.1 Å²	59.1	34%	0.337	33%	0.331	S	S	.	.	H	α-helix	trans	-62	-38	178.7	-55.4	-53.3	0	0	0	111.3	D69 T137 N142 D143 F144	D69-D140 HydrophobicContact CB-CB 4.44Å; T137-D140 WeakPolarHBondContact CB-OD2 3.36Å; T137-D140 WeakPolarHBondContact CG2-OD2 3.42Å; T137-D140 PolarHBondContact O-N 2.99Å; T137-D140 VanDerWaalsContact OG1-CG 3.26Å; T137-D140 PolarHBondContact OG1-N 3.02Å; T137-D140 VanDerWaalsContact OG1-N 3.14Å; T137-D140 PolarHBondContact OG1-OD2 2.86Å; D140-N142 VanDerWaalsContact C-N 3.3Å; D140-N142 PolarHBondContact O-N 3.38Å; D140-D143 PolarHBondContact O-N 3.37Å; D140-F144 VanDerWaalsContact O-CD1 3.25Å; D140-F144 WeakPolarHBondContact O-CD1 3.31Å
141	F	96.8	Very high	94.2	Very high	21 Å²	21	61.4 Å²	61.4	9%	0.092	35%	0.351	C	S	.	.	H	α-helix	trans	-60.5	-39.4	172.5	178.1	-112.6	0	0	0	112.7	F73 M136 T137 L139 D143 F144 R145 L148 M336 L337	F73-F141 HydrophobicContact CD2-CE2 4.27Å; F73-F141 AromaticContact CE2-CE2 3.96Å; F73-F141 HydrophobicContact CE2-CE2 3.96Å; M136-F141 HydrophobicContact CE-CB 3.94Å; M136-F141 HydrophobicContact CE-CD2 3.59Å; M136-F141 HydrophobicContact CE-CE2 4.48Å; M136-F141 HydrophobicContact CE-CG 4.04Å; M136-F141 HydrophobicContact CG-CB 4.26Å; M136-F141 HydrophobicContact SD-CB 4Å; M136-F141 HydrophobicContact SD-CD2 4.14Å; T137-F141 WeakPolarHBondContact O-CB 3.27Å; T137-F141 PolarHBondContact O-N 3.07Å; L139-F141 VanDerWaalsContact C-N 3.27Å; L139-F141 PolarHBondContact O-N 3.24Å; F141-D143 PolarHBondContact O-N 3.15Å; F141-F144 HydrophobicContact CB-CE1 4.49Å; F141-F144 HydrophobicContact CD2-CE1 4.04Å; F141-F144 AromaticContact CD2-CE2 3.98Å; F141-F144 HydrophobicContact CD2-CE2 3.98Å; F141-F144 AromaticContact CD2-CZ 3.54Å; F141-F144 HydrophobicContact CD2-CZ 3.54Å; F141-F144 HydrophobicContact CE2-CE2 4.09Å; F141-F144 HydrophobicContact CE2-CZ 4.09Å; F141-F144 PolarHBondContact O-N 3.46Å; F141-R145 HydrophobicContact CE1-CB 4.33Å; F141-R145 HydrophobicContact CE1-CG 4.09Å; F141-R145 HydrophobicContact CZ-CB 4.34Å; F141-R145 HydrophobicContact CZ-CG 4.08Å; F141-R145 WeakPolarHBondContact O-CB 3.44Å; F141-R145 PolarHBondContact O-N 3.28Å; F141-R145 VanDerWaalsContact O-N 3.1Å; F141-L148 HydrophobicContact CE2-CD1 4.17Å; F141-M336 HydrophobicContact CB-SD 3.98Å; F141-M336 HydrophobicContact CD1-CB 4Å; F141-M336 HydrophobicContact CD1-SD 4.38Å; F141-M336 HydrophobicContact CE1-CB 4.25Å; F141-M336 HydrophobicContact CG-SD 4.22Å; F141-L337 HydrophobicContact CE1-CD2 3.76Å
142	N	95.5	Very high	93.7	Very high	77 Å²	77	59.4 Å²	59.4	41%	0.412	34%	0.337	S	S	.	.	H	α-helix	trans	-65.1	-28.8	-179	-176.6	89.3	0	0	0	112.1	A138 L139 D140 F144	A138-N142 WeakPolarHBondContact O-CB 3.32Å; A138-N142 PolarHBondContact O-N 3.46Å; L139-N142 WeakPolarHBondContact O-CA 3.26Å; L139-N142 WeakPolarHBondContact O-CB 3.33Å; L139-N142 PolarHBondContact O-N 3.19Å; D140-N142 VanDerWaalsContact C-N 3.3Å; D140-N142 PolarHBondContact O-N 3.38Å; N142-F144 VanDerWaalsContact C-N 3.33Å; N142-F144 PolarHBondContact O-N 3.31Å
143	D	96.8	Very high	92.9	Very high	81 Å²	81	58.9 Å²	58.9	43%	0.433	35%	0.346	S	S	.	.	H	α-helix	trans	-70	-25.6	-176.9	-67.3	-14.6	0	0	0	113.8	I67 L139 D140 F141	I67-D143 HydrophobicContact CD1-CB 4.14Å; I67-D143 HydrophobicContact CG1-CB 4.37Å; I67-D143 HydrophobicContact CG2-CB 4.36Å; L139-D143 PolarHBondContact O-N 2.97Å; D140-D143 PolarHBondContact O-N 3.37Å; F141-D143 PolarHBondContact O-N 3.15Å
144	F	96.9	Very high	92.1	Very high	0 Å²	0	59.6 Å²	59.6	0%	0	35%	0.349	C	S	.	.	H	α-helix	trans	-113.6	-6.5	175.9	70.5	-92.4	0	0	0	114.5	I67 D69 E70 F73 M136 D140 F141 N142 E146 Y147 L148	I67-F144 HydrophobicContact CB-CB 3.94Å; I67-F144 HydrophobicContact CB-CD1 4.4Å; I67-F144 HydrophobicContact CG1-CB 3.94Å; I67-F144 HydrophobicContact CG2-CB 4.17Å; I67-F144 HydrophobicContact CG2-CD1 3.79Å; I67-F144 HydrophobicContact CG2-CG 4.42Å; D69-F144 HydrophobicContact CB-CE1 4.21Å; E70-F144 HydrophobicContact CB-CB 4.39Å; E70-F144 HydrophobicContact CB-CD1 4.33Å; E70-F144 HydrophobicContact CB-CD2 4Å; E70-F144 HydrophobicContact CB-CE2 4.29Å; E70-F144 HydrophobicContact CB-CG 4.01Å; E70-F144 HydrophobicContact CG-CD2 3.88Å; E70-F144 HydrophobicContact CG-CE2 4.21Å; E70-F144 HydrophobicContact CG-CG 4.33Å; F73-F144 HydrophobicContact CB-CE2 3.98Å; F73-F144 HydrophobicContact CB-CZ 3.84Å; F73-F144 HydrophobicContact CD1-CE2 4.27Å; F73-F144 HydrophobicContact CD2-CE2 4.19Å; F73-F144 HydrophobicContact CD2-CZ 4.19Å; F73-F144 AromaticContact CG-CE2 3.9Å; F73-F144 HydrophobicContact CG-CE2 3.9Å; F73-F144 HydrophobicContact CG-CZ 4.08Å; M136-F144 HydrophobicContact CE-CZ 4.29Å; M136-F144 HydrophobicContact SD-CE1 3.61Å; M136-F144 HydrophobicContact SD-CZ 3.61Å; D140-F144 VanDerWaalsContact O-CD1 3.25Å; D140-F144 WeakPolarHBondContact O-CD1 3.31Å; F141-F144 HydrophobicContact CB-CE1 4.49Å; F141-F144 HydrophobicContact CD2-CE1 4.04Å; F141-F144 AromaticContact CD2-CE2 3.98Å; F141-F144 HydrophobicContact CD2-CE2 3.98Å; F141-F144 AromaticContact CD2-CZ 3.54Å; F141-F144 HydrophobicContact CD2-CZ 3.54Å; F141-F144 HydrophobicContact CE2-CE2 4.09Å; F141-F144 HydrophobicContact CE2-CZ 4.09Å; F141-F144 PolarHBondContact O-N 3.46Å; N142-F144 VanDerWaalsContact C-N 3.33Å; N142-F144 PolarHBondContact O-N 3.31Å; F144-E146 PolarHBondContact O-N 3.23Å; F144-E146 VanDerWaalsContact O-N 3.12Å; F144-Y147 HydrophobicContact CB-CD2 3.96Å; F144-Y147 HydrophobicContact CB-CE2 4.32Å; F144-Y147 VanDerWaalsContact O-CD2 3.31Å; F144-Y147 WeakPolarHBondContact O-CD2 3.43Å; F144-Y147 PolarHBondContact O-N 3.3Å; F144-Y147 VanDerWaalsContact O-N 3.07Å; F144-L148 HydrophobicContact CD2-CD1 4.27Å; F144-L148 HydrophobicContact CD2-CG 4.44Å; F144-L148 HydrophobicContact CE2-CD1 4.12Å
145	R	94.1	Very high	91.6	Very high	53 Å²	53	60.6 Å²	60.6	20%	0.2	35%	0.353	C	S	.	.	G	3₁₀ helix	trans	-55.9	-32.5	-178.3	-177	-178.9	-176.6	-87.6	1.9	113.3	F141 Y147 L148 A341 T343	F141-R145 HydrophobicContact CE1-CB 4.33Å; F141-R145 HydrophobicContact CE1-CG 4.09Å; F141-R145 HydrophobicContact CZ-CB 4.34Å; F141-R145 HydrophobicContact CZ-CG 4.08Å; F141-R145 WeakPolarHBondContact O-CB 3.44Å; F141-R145 PolarHBondContact O-N 3.28Å; F141-R145 VanDerWaalsContact O-N 3.1Å; R145-Y147 PolarHBondContact O-N 2.84Å; R145-L148 PolarHBondContact O-N 3.39Å; R145-A341 PolarHBondContact NH2-O 2.86Å; R145-T343 HydrophobicContact CG-CG2 4.43Å
146	E	93	Very high	91.4	Very high	131 Å²	131	56.5 Å²	56.5	61%	0.612	33%	0.329	S	S	*	.	G	3₁₀ helix	trans	-60.9	-32.1	179.9	63.3	174.9	166.7	0	0	113	F144 L148	F144-E146 PolarHBondContact O-N 3.23Å; F144-E146 VanDerWaalsContact O-N 3.12Å; E146-L148 VanDerWaalsContact C-N 3.26Å; E146-L148 PolarHBondContact O-N 3.1Å
147	Y	94	Very high	91.3	Very high	47 Å²	47	57.8 Å²	57.8	18%	0.184	34%	0.336	C	S	.	.	G	3₁₀ helix	trans	-76.4	-14.2	-178.8	-49.5	-58.8	0	0	0	113.2	S60 K63 N65 F144 R145	S60-Y147 VanDerWaalsContact CB-CD2 3.44Å; S60-Y147 VanDerWaalsContact CB-CE2 3.41Å; K63-Y147 HydrophobicContact CB-CD1 4.2Å; K63-Y147 HydrophobicContact CB-CE1 3.92Å; K63-Y147 HydrophobicContact CG-CD1 3.85Å; K63-Y147 HydrophobicContact CG-CE1 4.06Å; N65-Y147 PolarHBondContact ND2-OH 2.91Å; N65-Y147 VanDerWaalsContact ND2-OH 3.12Å; F144-Y147 HydrophobicContact CB-CD2 3.96Å; F144-Y147 HydrophobicContact CB-CE2 4.32Å; F144-Y147 VanDerWaalsContact O-CD2 3.31Å; F144-Y147 WeakPolarHBondContact O-CD2 3.43Å; F144-Y147 PolarHBondContact O-N 3.3Å; F144-Y147 VanDerWaalsContact O-N 3.07Å; R145-Y147 PolarHBondContact O-N 2.84Å
148	L	90.4	Very high	91.3	Very high	31 Å²	31	56.8 Å²	56.8	16%	0.162	33%	0.327	C	S	.	.	G	3₁₀ helix	trans	-85.5	-21	-178.1	-56.9	-179.5	0	0	0	113.1	F73 F141 F144 R145 E146 A151	F73-L148 HydrophobicContact CE1-CD1 4.01Å; F73-L148 HydrophobicContact CE1-CD2 4.25Å; F73-L148 HydrophobicContact CE2-CD1 4.5Å; F73-L148 HydrophobicContact CZ-CD1 3.91Å; F141-L148 HydrophobicContact CE2-CD1 4.17Å; F144-L148 HydrophobicContact CD2-CD1 4.27Å; F144-L148 HydrophobicContact CD2-CG 4.44Å; F144-L148 HydrophobicContact CE2-CD1 4.12Å; R145-L148 PolarHBondContact O-N 3.39Å; E146-L148 VanDerWaalsContact C-N 3.26Å; E146-L148 PolarHBondContact O-N 3.1Å; L148-A151 WeakPolarHBondContact O-CA 3.42Å; L148-A151 WeakPolarHBondContact O-CB 3.42Å; L148-A151 PolarHBondContact O-N 3.37Å
149	S	84.7	Confident	91.4	Very high	79 Å²	79	55.7 Å²	55.7	55%	0.552	32%	0.316	S	S	*	.	T	Hydrogen-bonded Turn	trans	-69.7	133.3	-174.8	-170.4	0	0	0	0	111.4
150	P	82.2	Confident	91.4	Very high	100 Å²	100	49.9 Å²	49.9	65%	0.649	28%	0.284	S	S	*	.	T	Hydrogen-bonded Turn	cis	-97.4	14	6.6	38.3	-36.3	0	0	0	114.9
151	A	81.3	Confident	91.4	Very high	53 Å²	53	47.4 Å²	47.4	44%	0.438	27%	0.271	S	S	.	.			trans	-62.3	142.5	-177.5	0	0	0	0	0	112.2	L148 Q155 T343	L148-A151 WeakPolarHBondContact O-CA 3.42Å; L148-A151 WeakPolarHBondContact O-CB 3.42Å; L148-A151 PolarHBondContact O-N 3.37Å; A151-Q155 VanDerWaalsContact CA-OE1 3.32Å; A151-T343 PolarHBondContact O-OG1 3.49Å
152	S	85.3	Confident	91.5	Very high	30 Å²	30	46.4 Å²	46.4	21%	0.21	27%	0.267	C	S	.	.			trans	-158.6	164.1	178.3	70.7	0	0	0	0	113	F154 Q155 G344	S152-F154 PolarHBondContact O-N 3.29Å; S152-F154 WeakPolarHBondContact OG-CB 3.33Å; S152-F154 WeakPolarHBondContact OG-CD2 3.4Å; S152-F154 PolarHBondContact OG-N 2.87Å; S152-Q155 VanDerWaalsContact N-OE1 3.12Å; S152-Q155 WeakPolarHBondContact O-CB 3.19Å; S152-Q155 PolarHBondContact O-N 2.98Å; S152-G344 WeakPolarHBondContact OG-CA 3.31Å
153	G	81.3	Confident	91.6	Very high	60 Å²	60	42.7 Å²	42.7	62%	0.619	25%	0.247	S	C	*	.	G	3₁₀ helix	trans	-59.5	-10	174.3	0	0	0	0	0	115	Q155 S156	G153-Q155 PolarHBondContact O-N 3.21Å; G153-S156 PolarHBondContact O-N 2.88Å
154	F	82.2	Confident	91.6	Very high	18 Å²	18	39.2 Å²	39.2	8%	0.079	23%	0.228	C	C	.	.	G	3₁₀ helix	trans	-61.2	-23.6	168.2	-73.9	-67.1	0	0	0	113.2	S152 Y176 F185 Y351	S152-F154 PolarHBondContact O-N 3.29Å; S152-F154 WeakPolarHBondContact OG-CB 3.33Å; S152-F154 WeakPolarHBondContact OG-CD2 3.4Å; S152-F154 PolarHBondContact OG-N 2.87Å; F154-Y176 HydrophobicContact CZ-CD1 4.26Å; F154-F185 WeakPolarHBondContact O-CZ 3.46Å; F154-Y351 HydrophobicContact CE1-CD1 4.14Å; F154-Y351 AromaticContact CE1-CE1 3.32Å; F154-Y351 HydrophobicContact CE1-CE1 3.32Å; F154-Y351 HydrophobicContact CE1-CE2 4.5Å; F154-Y351 AromaticContact CE1-CZ 3.54Å; F154-Y351 AromaticContact CZ-CD1 3.6Å; F154-Y351 HydrophobicContact CZ-CD1 3.6Å; F154-Y351 AromaticContact CZ-CE1 3.28Å; F154-Y351 HydrophobicContact CZ-CE1 3.28Å; F154-Y351 HydrophobicContact CZ-CG 4.37Å; F154-Y351 AromaticContact CZ-CZ 3.81Å
155	Q	86	Confident	91.7	Very high	92 Å²	92	40 Å²	40	43%	0.43	23%	0.232	S	C	.	.	G	3₁₀ helix	trans	-94.3	7.5	179.9	-61.8	166.8	-54.4	0	0	112.7	A151 S152 G153 L157 N184 F185	A151-Q155 VanDerWaalsContact CA-OE1 3.32Å; S152-Q155 VanDerWaalsContact N-OE1 3.12Å; S152-Q155 WeakPolarHBondContact O-CB 3.19Å; S152-Q155 PolarHBondContact O-N 2.98Å; G153-Q155 PolarHBondContact O-N 3.21Å; Q155-L157 PolarHBondContact O-N 3.43Å; Q155-N184 HydrophobicContact CG-CB 4.2Å; Q155-F185 VanDerWaalsContact O-CE1 3.32Å; Q155-F185 WeakPolarHBondContact O-CE1 3.47Å
156	S	94.6	Very high	91.9	Very high	17 Å²	17	37.9 Å²	37.9	12%	0.119	22%	0.224	C	C	.	.			trans	-71.4	100.6	170.4	175.3	0	0	0	0	109.4	E81 G153 F159 R160	E81-S156 WeakPolarHBondContact OE1-CB 3.2Å; E81-S156 PolarHBondContact OE1-OG 3.49Å; G153-S156 PolarHBondContact O-N 2.88Å; S156-F159 PolarHBondContact O-N 2.79Å; S156-F159 VanDerWaalsContact OG-CB 3.31Å; S156-F159 WeakPolarHBondContact OG-CB 3.33Å; S156-F159 PolarHBondContact OG-N 3.05Å; S156-R160 PolarHBondContact O-N 3.4Å
157	L	95.6	Very high	92.2	Very high	29 Å²	29	31.9 Å²	31.9	15%	0.152	20%	0.197	C	C	.	.	H	α-helix	trans	-58.4	-49.6	179.2	175.8	64.1	0	0	0	110.8	Q155 F159 R160 L161 F185 D189 M192 L193	Q155-L157 PolarHBondContact O-N 3.43Å; L157-F159 VanDerWaalsContact C-N 3.31Å; L157-F159 PolarHBondContact O-N 3.02Å; L157-R160 PolarHBondContact O-N 2.61Å; L157-R160 VanDerWaalsContact O-N 3.1Å; L157-L161 HydrophobicContact CD1-CD1 4.24Å; L157-L161 HydrophobicContact CD1-CG 4.21Å; L157-L161 HydrophobicContact CD2-CD1 4.38Å; L157-L161 HydrophobicContact CG-CD1 3.88Å; L157-L161 HydrophobicContact CG-CG 4.28Å; L157-L161 WeakPolarHBondContact O-CG 3.47Å; L157-L161 PolarHBondContact O-N 2.96Å; L157-F185 HydrophobicContact CB-CD1 4.42Å; L157-F185 HydrophobicContact CB-CE1 3.81Å; L157-F185 HydrophobicContact CD1-CD1 4.15Å; L157-F185 HydrophobicContact CD1-CE1 4.13Å; L157-D189 HydrophobicContact CD1-CB 4.12Å; L157-D189 HydrophobicContact CD2-CB 4.3Å; L157-D189 WeakPolarHBondContact CD2-OD1 3.49Å; L157-M192 HydrophobicContact CD2-SD 4.18Å; L157-L193 HydrophobicContact CD1-CD1 3.95Å; L157-L193 HydrophobicContact CD1-CD2 3.9Å; L157-L193 HydrophobicContact CD1-CG 3.65Å
158	Q	97.9	Very high	92.3	Very high	39 Å²	39	30.1 Å²	30.1	18%	0.182	19%	0.192	C	C	.	.	H	α-helix	trans	-64.7	-36.4	-174.9	-62.6	-166.2	102	0	0	112.1	E81 F84 L88 R160 L161 L162	E81-Q158 PolarHBondContact O-NE2 3.19Å; E81-Q158 WeakPolarHBondContact OE2-CB 3.34Å; E81-Q158 PolarHBondContact OE2-NE2 2.91Å; F84-Q158 HydrophobicContact CB-CB 3.9Å; L88-Q158 HydrophobicContact CD1-CB 3.78Å; L88-Q158 HydrophobicContact CD1-CG 4.01Å; Q158-R160 VanDerWaalsContact C-N 3.31Å; Q158-R160 PolarHBondContact O-N 3.36Å; Q158-L161 PolarHBondContact O-N 2.79Å; Q158-L162 VanDerWaalsContact O-CB 3.26Å; Q158-L162 WeakPolarHBondContact O-CB 3.31Å; Q158-L162 PolarHBondContact O-N 2.73Å
159	F	97.1	Very high	92.4	Very high	13 Å²	13	32.5 Å²	32.5	6%	0.057	20%	0.204	C	C	.	.	H	α-helix	trans	-63.7	-37.1	175	-171.3	-101.3	0	0	0	112.3	F84 S156 L157 E163 W325	F84-F159 HydrophobicContact CE1-CD2 4.28Å; F84-F159 HydrophobicContact CE2-CB 4.41Å; F84-F159 HydrophobicContact CE2-CD2 4.32Å; F84-F159 AromaticContact CZ-CD2 3.93Å; F84-F159 HydrophobicContact CZ-CD2 3.93Å; S156-F159 PolarHBondContact O-N 2.79Å; S156-F159 VanDerWaalsContact OG-CB 3.31Å; S156-F159 WeakPolarHBondContact OG-CB 3.33Å; S156-F159 PolarHBondContact OG-N 3.05Å; L157-F159 VanDerWaalsContact C-N 3.31Å; L157-F159 PolarHBondContact O-N 3.02Å; F159-E163 HydrophobicContact CE1-CG 4.22Å; F159-E163 VanDerWaalsContact CE1-OE1 3.32Å; F159-E163 WeakPolarHBondContact CE1-OE1 3.49Å; F159-E163 WeakPolarHBondContact O-CG 3.42Å; F159-E163 PolarHBondContact O-N 3.04Å; F159-E163 VanDerWaalsContact O-N 3.12Å; F159-W325 HydrophobicContact CD2-CH2 4.17Å; F159-W325 HydrophobicContact CD2-CZ3 4.24Å; F159-W325 HydrophobicContact CE1-CZ3 4.31Å; F159-W325 AromaticContact CE2-CE3 3.81Å; F159-W325 HydrophobicContact CE2-CE3 3.81Å; F159-W325 AromaticContact CE2-CH2 3.73Å; F159-W325 HydrophobicContact CE2-CH2 3.73Å; F159-W325 HydrophobicContact CE2-CZ2 4.46Å; F159-W325 AromaticContact CE2-CZ3 3.35Å; F159-W325 HydrophobicContact CE2-CZ3 3.35Å; F159-W325 HydrophobicContact CZ-CE3 4.01Å; F159-W325 HydrophobicContact CZ-CH2 4.06Å; F159-W325 AromaticContact CZ-CZ3 3.4Å; F159-W325 HydrophobicContact CZ-CZ3 3.4Å
160	R	96.3	Very high	92.7	Very high	13 Å²	13	32 Å²	32	5%	0.049	19%	0.193	C	C	.	.	H	α-helix	trans	-72.1	-42.1	175.1	-65.6	-57.7	175.8	-143.5	-5.8	112.7	S156 L157 Q158 L162 E163 N164 Y181 F185 L193	S156-R160 PolarHBondContact O-N 3.4Å; L157-R160 PolarHBondContact O-N 2.61Å; L157-R160 VanDerWaalsContact O-N 3.1Å; Q158-R160 VanDerWaalsContact C-N 3.31Å; Q158-R160 PolarHBondContact O-N 3.36Å; R160-L162 PolarHBondContact O-N 2.94Å; R160-E163 VanDerWaalsContact CD-OE2 3.32Å; R160-E163 WeakPolarHBondContact CD-OE2 3.41Å; R160-E163 IonicContact CZ-OE2 3.15Å; R160-E163 IonicContact NE-OE2 2.66Å; R160-E163 VanDerWaalsContact NH1-CD 3.33Å; R160-E163 IonicContact NH1-OE1 3.3Å; R160-E163 PolarHBondContact NH1-OE1 3.42Å; R160-E163 IonicContact NH1-OE2 3.88Å; R160-E163 PolarHBondContact NH1-OE2 3.38Å; R160-E163 PolarHBondContact O-N 3.3Å; R160-N164 WeakPolarHBondContact O-CB 3.46Å; R160-N164 PolarHBondContact O-N 3.19Å; R160-N164 PolarHBondContact O-ND2 3.22Å; R160-N164 PolarHBondContact O-OD1 3.03Å; R160-Y181 HydrophobicContact CB-CD2 4.29Å; R160-Y181 HydrophobicContact CB-CE2 3.93Å; R160-Y181 HydrophobicContact CG-CD2 3.79Å; R160-Y181 HydrophobicContact CG-CE2 3.96Å; R160-F185 HydrophobicContact CG-CE2 4.17Å; R160-F185 HydrophobicContact CG-CZ 4.14Å; R160-L193 HydrophobicContact CB-CD2 3.55Å
161	L	97.8	Very high	93.1	Very high	11 Å²	11	32.1 Å²	32.1	6%	0.058	20%	0.196	C	C	.	.	H	α-helix	trans	-57.2	-41.7	172.5	-69.6	173.3	0	0	0	111.2	L88 L157 Q158 N164 K165 M192 L193	L88-L161 HydrophobicContact CD1-CB 4.26Å; L88-L161 HydrophobicContact CD1-CD1 4.45Å; L88-L161 HydrophobicContact CD2-CB 4.01Å; L157-L161 HydrophobicContact CD1-CD1 4.24Å; L157-L161 HydrophobicContact CD1-CG 4.21Å; L157-L161 HydrophobicContact CD2-CD1 4.38Å; L157-L161 HydrophobicContact CG-CD1 3.88Å; L157-L161 HydrophobicContact CG-CG 4.28Å; L157-L161 WeakPolarHBondContact O-CG 3.47Å; L157-L161 PolarHBondContact O-N 2.96Å; Q158-L161 PolarHBondContact O-N 2.79Å; L161-N164 PolarHBondContact O-N 3.42Å; L161-K165 VanDerWaalsContact O-CB 3.27Å; L161-K165 WeakPolarHBondContact O-CB 3.23Å; L161-K165 VanDerWaalsContact O-CG 3.27Å; L161-K165 WeakPolarHBondContact O-CG 3.41Å; L161-K165 PolarHBondContact O-N 2.87Å; L161-M192 HydrophobicContact CD1-CE 4.05Å; L161-M192 HydrophobicContact CD2-CB 4.37Å; L161-L193 HydrophobicContact CD2-CD2 3.92Å; L161-L193 HydrophobicContact CG-CD2 4.12Å
162	L	97.9	Very high	93.7	Very high	0 Å²	0	30.3 Å²	30.3	0%	0	18%	0.179	C	C	.	.	H	α-helix	trans	-62.2	-50.5	178	178.6	60.8	0	0	0	111.7	F84 I87 L88 L91 F123 Q158 R160 N164 K165 I166 M322	F84-L162 HydrophobicContact CD1-CD2 4.36Å; I87-L162 HydrophobicContact CG2-CD1 3.46Å; I87-L162 VanDerWaalsContact CG2-CD1 3.46Å; I87-L162 HydrophobicContact CG2-CD2 4.48Å; L88-L162 HydrophobicContact CD2-CB 4.21Å; L91-L162 HydrophobicContact CD2-CD1 4.06Å; F123-L162 HydrophobicContact CE1-CD2 4.37Å; F123-L162 HydrophobicContact CZ-CD2 3.83Å; Q158-L162 VanDerWaalsContact O-CB 3.26Å; Q158-L162 WeakPolarHBondContact O-CB 3.31Å; Q158-L162 PolarHBondContact O-N 2.73Å; R160-L162 PolarHBondContact O-N 2.94Å; L162-N164 VanDerWaalsContact C-N 3.33Å; L162-N164 PolarHBondContact O-N 3.21Å; L162-K165 PolarHBondContact O-N 2.76Å; L162-I166 HydrophobicContact CD1-CD1 3.73Å; L162-I166 HydrophobicContact CD1-CG1 4.17Å; L162-I166 HydrophobicContact CG-CD1 4.01Å; L162-I166 VanDerWaalsContact O-CG1 3.25Å; L162-I166 WeakPolarHBondContact O-CG1 3.27Å; L162-I166 PolarHBondContact O-N 2.98Å; L162-M322 HydrophobicContact CD2-SD 4.27Å
163	E	97.9	Very high	94	Very high	0 Å²	0	29.8 Å²	29.8	0%	0	17%	0.172	C	C	.	.	H	α-helix	trans	-58	-44.9	176.5	-73.1	175.8	141.9	0	0	111.9	F159 R160 G167 V168 R173 M322 R326	F159-E163 HydrophobicContact CE1-CG 4.22Å; F159-E163 VanDerWaalsContact CE1-OE1 3.32Å; F159-E163 WeakPolarHBondContact CE1-OE1 3.49Å; F159-E163 WeakPolarHBondContact O-CG 3.42Å; F159-E163 PolarHBondContact O-N 3.04Å; F159-E163 VanDerWaalsContact O-N 3.12Å; R160-E163 VanDerWaalsContact CD-OE2 3.32Å; R160-E163 WeakPolarHBondContact CD-OE2 3.41Å; R160-E163 IonicContact CZ-OE2 3.15Å; R160-E163 IonicContact NE-OE2 2.66Å; R160-E163 VanDerWaalsContact NH1-CD 3.33Å; R160-E163 IonicContact NH1-OE1 3.3Å; R160-E163 PolarHBondContact NH1-OE1 3.42Å; R160-E163 IonicContact NH1-OE2 3.88Å; R160-E163 PolarHBondContact NH1-OE2 3.38Å; R160-E163 PolarHBondContact O-N 3.3Å; E163-G167 PolarHBondContact O-N 3.34Å; E163-G167 VanDerWaalsContact O-N 3.1Å; E163-V168 HydrophobicContact CB-CB 4.09Å; E163-V168 HydrophobicContact CB-CG2 3.9Å; E163-V168 HydrophobicContact CG-CG2 4.28Å; E163-V168 WeakPolarHBondContact O-CB 3.44Å; E163-V168 WeakPolarHBondContact O-CG2 3.44Å; E163-V168 PolarHBondContact O-N 3.3Å; E163-R173 VanDerWaalsContact CD-NH1 3.32Å; E163-R173 IonicContact OE1-NH1 2.74Å; E163-R173 IonicContact OE2-CZ 2.88Å; E163-R173 IonicContact OE2-NH1 3.93Å; E163-R173 PolarHBondContact OE2-NH1 3.38Å; E163-R173 IonicContact OE2-NH2 2.69Å; E163-R173 PolarHBondContact OE2-NH2 3.21Å; E163-M322 HydrophobicContact CG-CE 4.14Å; E163-R326 IonicContact OE1-CZ 3.4Å; E163-R326 VanDerWaalsContact OE1-CZ 3.22Å; E163-R326 IonicContact OE1-NH1 2.73Å; E163-R326 PolarHBondContact OE1-NH1 3.47Å; E163-R326 IonicContact OE1-NH2 3.38Å; E163-R326 PolarHBondContact OE1-NH2 2.91Å
164	N	98.1	Very high	94.4	Very high	8 Å²	8	28.4 Å²	28.4	4%	0.043	15%	0.152	C	C	.	.	H	α-helix	trans	-65.2	-50	180	-66.7	-9.5	0	0	0	111.4	R160 L161 L162 I166 G167 R173 Y181 S196 T201	R160-N164 WeakPolarHBondContact O-CB 3.46Å; R160-N164 PolarHBondContact O-N 3.19Å; R160-N164 PolarHBondContact O-ND2 3.22Å; R160-N164 PolarHBondContact O-OD1 3.03Å; L161-N164 PolarHBondContact O-N 3.42Å; L162-N164 VanDerWaalsContact C-N 3.33Å; L162-N164 PolarHBondContact O-N 3.21Å; N164-I166 VanDerWaalsContact C-N 3.32Å; N164-I166 PolarHBondContact O-N 2.95Å; N164-G167 WeakPolarHBondContact O-CA 3.35Å; N164-G167 PolarHBondContact O-N 3.05Å; N164-G167 VanDerWaalsContact O-N 3.12Å; N164-R173 PolarHBondContact OD1-NH2 3.1Å; N164-Y181 PolarHBondContact ND2-OH 3.22Å; N164-S196 WeakPolarHBondContact CB-OG 3.23Å; N164-S196 PolarHBondContact ND2-OG 2.86Å; N164-T201 VanDerWaalsContact O-CG2 3.29Å; N164-T201 WeakPolarHBondContact O-CG2 3.37Å
165	K	98.5	Very high	94.4	Very high	17 Å²	17	32.3 Å²	32.3	7%	0.074	18%	0.179	C	C	.	.	H	α-helix	trans	-66.3	-29.9	-177.4	-73.3	167.2	176.7	-75.5	0	113.1	L88 L91 D92 R95 L161 L162 E199 L202	L88-K165 HydrophobicContact CD2-CD 3.67Å; L91-K165 HydrophobicContact CD2-CB 3.55Å; L91-K165 HydrophobicContact CG-CB 4.35Å; D92-K165 VanDerWaalsContact CG-NZ 3.3Å; D92-K165 WeakPolarHBondContact OD1-CD 3.33Å; D92-K165 WeakPolarHBondContact OD1-CE 3.46Å; D92-K165 IonicContact OD1-NZ 3.7Å; D92-K165 PolarHBondContact OD1-NZ 3.41Å; D92-K165 IonicContact OD2-NZ 3.22Å; D92-K165 PolarHBondContact OD2-NZ 3.29Å; D92-K165 VanDerWaalsContact OD2-NZ 3.07Å; R95-K165 VanDerWaalsContact NH1-NZ 3.12Å; L161-K165 VanDerWaalsContact O-CB 3.27Å; L161-K165 WeakPolarHBondContact O-CB 3.23Å; L161-K165 VanDerWaalsContact O-CG 3.27Å; L161-K165 WeakPolarHBondContact O-CG 3.41Å; L161-K165 PolarHBondContact O-N 2.87Å; L162-K165 PolarHBondContact O-N 2.76Å; K165-E199 IonicContact NZ-OE2 3.14Å; K165-L202 PolarHBondContact O-N 2.98Å
166	I	98.4	Very high	93.9	Very high	7 Å²	7	30 Å²	30	4%	0.036	17%	0.167	C	C	.	.	H	α-helix	trans	-69.9	-48	170.7	-64.1	170.2	0	0	0	109.8	L91 L162 N164 L203 I318 M322 V362 F363	L91-I166 HydrophobicContact CD2-CG1 3.84Å; L162-I166 HydrophobicContact CD1-CD1 3.73Å; L162-I166 HydrophobicContact CD1-CG1 4.17Å; L162-I166 HydrophobicContact CG-CD1 4.01Å; L162-I166 VanDerWaalsContact O-CG1 3.25Å; L162-I166 WeakPolarHBondContact O-CG1 3.27Å; L162-I166 PolarHBondContact O-N 2.98Å; N164-I166 VanDerWaalsContact C-N 3.32Å; N164-I166 PolarHBondContact O-N 2.95Å; I166-L203 PolarHBondContact O-N 3.18Å; I166-L203 VanDerWaalsContact O-N 3.07Å; I166-I318 HydrophobicContact CD1-CG2 4.23Å; I166-M322 HydrophobicContact CD1-CE 4.34Å; I166-V362 HydrophobicContact CG2-CB 3.95Å; I166-V362 HydrophobicContact CG2-CG1 4.08Å; I166-V362 HydrophobicContact CG2-CG2 3.81Å; I166-F363 HydrophobicContact CG2-CE2 4.01Å
167	G	97.8	Very high	92.4	Very high	5 Å²	5	34.1 Å²	34.1	5%	0.052	19%	0.187	C	C	.	.	T	Hydrogen-bonded Turn	trans	135.7	28.3	175.5	0	0	0	0	0	115.6	E163 N164 L169	E163-G167 PolarHBondContact O-N 3.34Å; E163-G167 VanDerWaalsContact O-N 3.1Å; N164-G167 WeakPolarHBondContact O-CA 3.35Å; N164-G167 PolarHBondContact O-N 3.05Å; N164-G167 VanDerWaalsContact O-N 3.12Å; G167-L169 PolarHBondContact O-N 3.33Å
168	V	97.1	Very high	91	Very high	11 Å²	11	44.7 Å²	44.7	7%	0.067	23%	0.225	C	C	.	.			trans	-68.9	112.6	174	178	0	0	0	0	109.5	E163 R173 Y360 V362	E163-V168 HydrophobicContact CB-CB 4.09Å; E163-V168 HydrophobicContact CB-CG2 3.9Å; E163-V168 HydrophobicContact CG-CG2 4.28Å; E163-V168 WeakPolarHBondContact O-CB 3.44Å; E163-V168 WeakPolarHBondContact O-CG2 3.44Å; E163-V168 PolarHBondContact O-N 3.3Å; V168-R173 HydrophobicContact CG1-CG 4.15Å; V168-Y360 HydrophobicContact CG1-CD1 3.78Å; V168-Y360 HydrophobicContact CG1-CE1 4.16Å; V168-V362 HydrophobicContact CB-CG2 4.49Å; V168-V362 HydrophobicContact CG2-CG2 3.66Å
169	L	92.7	Very high	89.7	Confident	80 Å²	80	51.6 Å²	51.6	42%	0.419	25%	0.25	S	C	.	.			trans	-69.1	136.8	-179.4	-61.7	176.5	0	0	0	111.9	G167 S171 L172 R173	G167-L169 PolarHBondContact O-N 3.33Å; L169-S171 VanDerWaalsContact C-N 3.29Å; L169-S171 PolarHBondContact O-N 3.14Å; L169-L172 HydrophobicContact CB-CB 4.4Å; L169-L172 HydrophobicContact CB-CD1 3.99Å; L169-L172 HydrophobicContact CB-CG 4.02Å; L169-L172 HydrophobicContact CD1-CD1 3.97Å; L169-L172 HydrophobicContact CD1-CG 4.45Å; L169-L172 HydrophobicContact CG-CD1 4.32Å; L169-L172 PolarHBondContact O-N 3.34Å; L169-R173 PolarHBondContact O-N 3.15Å
170	Q	90.9	Very high	88.8	Confident	70 Å²	70	53.8 Å²	53.8	33%	0.327	26%	0.26	S	S	.	.	G	3₁₀ helix	trans	-58.5	-39.9	179	177.6	54.7	17.4	0	0	113	L172 R173 H180	Q170-L172 PolarHBondContact O-N 2.88Å; Q170-R173 PolarHBondContact O-N 3.21Å; Q170-H180 VanDerWaalsContact CD-CE1 3.48Å; Q170-H180 WeakPolarHBondContact CG-NE2 3.48Å; Q170-H180 PolarHBondContact NE2-CD2 2.75Å; Q170-H180 PolarHBondContact NE2-CE1 3.18Å; Q170-H180 PolarHBondContact NE2-NE2 3.41Å
171	S	91.3	Very high	88.3	Confident	101 Å²	101	54.1 Å²	54.1	71%	0.706	26%	0.261	S	S	*	.	G	3₁₀ helix	trans	-64.1	-22.3	178.6	55.3	0	0	0	0	113.8	L169	L169-S171 VanDerWaalsContact C-N 3.29Å; L169-S171 PolarHBondContact O-N 3.14Å
172	L	92.4	Very high	87.8	Confident	16 Å²	16	56.3 Å²	56.3	8%	0.084	27%	0.269	C	S	.	.	G	3₁₀ helix	trans	-90.8	-16.5	-179.1	-64.2	-180	0	0	0	113.2	L169 Q170 V174 R284 R359	L169-L172 HydrophobicContact CB-CB 4.4Å; L169-L172 HydrophobicContact CB-CD1 3.99Å; L169-L172 HydrophobicContact CB-CG 4.02Å; L169-L172 HydrophobicContact CD1-CD1 3.97Å; L169-L172 HydrophobicContact CD1-CG 4.45Å; L169-L172 HydrophobicContact CG-CD1 4.32Å; L169-L172 PolarHBondContact O-N 3.34Å; Q170-L172 PolarHBondContact O-N 2.88Å; L172-V174 PolarHBondContact O-N 3.05Å; L172-R284 VanDerWaalsContact CD1-CZ 3.4Å; L172-R284 VanDerWaalsContact CD1-NE 3.35Å; L172-R284 VanDerWaalsContact CD1-NH2 3.26Å; L172-R359 HydrophobicContact CB-CB 4.47Å
173	R	93.1	Very high	87.2	Confident	18 Å²	18	60.9 Å²	60.9	7%	0.068	29%	0.294	C	S	.	.	S	Bend	trans	-62.4	137	178.9	-64.7	-174	-177.3	-88.1	6.3	110.3	E163 N164 V168 L169 Q170 P175 Y360	E163-R173 VanDerWaalsContact CD-NH1 3.32Å; E163-R173 IonicContact OE1-NH1 2.74Å; E163-R173 IonicContact OE2-CZ 2.88Å; E163-R173 IonicContact OE2-NH1 3.93Å; E163-R173 PolarHBondContact OE2-NH1 3.38Å; E163-R173 IonicContact OE2-NH2 2.69Å; E163-R173 PolarHBondContact OE2-NH2 3.21Å; N164-R173 PolarHBondContact OD1-NH2 3.1Å; V168-R173 HydrophobicContact CG1-CG 4.15Å; L169-R173 PolarHBondContact O-N 3.15Å; Q170-R173 PolarHBondContact O-N 3.21Å; R173-P175 WeakPolarHBondContact O-CD 3.35Å; R173-Y360 HydrophobicContact CG-CE1 4.24Å
174	V	89.1	Confident	86.7	Confident	32 Å²	32	64 Å²	64	19%	0.194	31%	0.31	C	S	.	.	P	Polyproline II helix	trans	-68.2	123.1	176.3	178.9	0	0	0	0	108.4	L172 S354 Y360	L172-V174 PolarHBondContact O-N 3.05Å; V174-S354 WeakPolarHBondContact CG1-OG 3.41Å; V174-Y360 HydrophobicContact CG2-CE2 4.11Å; V174-Y360 PolarHBondContact N-OH 3.29Å
175	P	83.1	Confident	86.3	Confident	100 Å²	100	64.3 Å²	64.3	65%	0.649	31%	0.311	S	S	*	.	P	Polyproline II helix	trans	-66.3	140.6	-178.5	26.8	-34.1	0	0	0	110.3	R173	R173-P175 WeakPolarHBondContact O-CD 3.35Å
176	Y	75.1	Confident	85.8	Confident	43 Å²	43	73.3 Å²	73.3	17%	0.169	35%	0.345	C	S	.	.	B	Isolated β-bridge	trans	-128.2	129.2	171	167.1	-111.4	0	0	0	108.5	F154 R178 R179 G344 G345 S346	F154-Y176 HydrophobicContact CZ-CD1 4.26Å; Y176-R178 PolarHBondContact O-N 3.19Å; Y176-R179 PolarHBondContact O-N 3.42Å; Y176-G344 PolarHBondContact OH-O 3.38Å; Y176-G345 VanDerWaalsContact CZ-C 3.49Å; Y176-G345 WeakPolarHBondContact OH-CA 3.25Å; Y176-G345 PolarHBondContact OH-O 2.91Å; Y176-S346 PolarHBondContact OH-N 3.02Å
177	N	62.1	Low	85.5	Confident	103 Å²	103	79.2 Å²	79.2	55%	0.551	38%	0.376	S	S	*	.	T	Hydrogen-bonded Turn	trans	50.1	23.3	-175.2	-79.1	0.9	0	0	0	115.8	R179	N177-R179 PolarHBondContact O-N 3.4Å; N177-R179 VanDerWaalsContact O-N 3.12Å
178	R	66.5	Low	85.2	Confident	252 Å²	252	86 Å²	86	95%	0.951	41%	0.407	S	S	*	.	T	Hydrogen-bonded Turn	trans	54	25.1	-174	-55.5	-179.6	177.2	175.5	-1.3	113.5	Y176	Y176-R178 PolarHBondContact O-N 3.19Å
179	R	70.9	Confident	84.9	Confident	184 Å²	184	88.7 Å²	88.7	69%	0.694	42%	0.421	S	S	*	.	B	Isolated β-bridge	trans	-111.2	154.1	-178.7	-80.6	-172.4	-169.4	-178	2	111	Y176 N177 D183	Y176-R179 PolarHBondContact O-N 3.42Å; N177-R179 PolarHBondContact O-N 3.4Å; N177-R179 VanDerWaalsContact O-N 3.12Å; R179-D183 WeakPolarHBondContact CB-OD2 3.42Å; R179-D183 WeakPolarHBondContact CG-OD2 3.42Å
180	H	79.1	Confident	84.9	Confident	58 Å²	58	87 Å²	87	27%	0.269	41%	0.412	S	S	.	.			trans	-72.2	144.3	175.2	-158.1	-83.9	0	0	0	108.4	Q170 R182 D183 E197	Q170-H180 VanDerWaalsContact CD-CE1 3.48Å; Q170-H180 WeakPolarHBondContact CG-NE2 3.48Å; Q170-H180 PolarHBondContact NE2-CD2 2.75Å; Q170-H180 PolarHBondContact NE2-CE1 3.18Å; Q170-H180 PolarHBondContact NE2-NE2 3.41Å; H180-R182 WeakPolarHBondContact ND1-CB 3.32Å; H180-R182 PolarHBondContact ND1-N 2.99Å; H180-R182 PolarHBondContact O-N 2.74Å; H180-D183 PolarHBondContact N-OD2 3.36Å; H180-D183 WeakPolarHBondContact O-CB 3.39Å; H180-D183 PolarHBondContact O-N 3.11Å; H180-E197 IonicContact CE1-OE1 2.84Å; H180-E197 PolarHBondContact CE1-OE1 3.41Å
181	Y	85.4	Confident	85	Confident	21 Å²	21	89.1 Å²	89.1	8%	0.082	42%	0.422	C	S	.	.	G	3₁₀ helix	trans	-59	-23.6	178.5	77	-91	0	0	0	112.3	R160 N164 D183 N184 L193 E197	R160-Y181 HydrophobicContact CB-CD2 4.29Å; R160-Y181 HydrophobicContact CB-CE2 3.93Å; R160-Y181 HydrophobicContact CG-CD2 3.79Å; R160-Y181 HydrophobicContact CG-CE2 3.96Å; N164-Y181 PolarHBondContact ND2-OH 3.22Å; Y181-D183 VanDerWaalsContact C-N 3.32Å; Y181-N184 PolarHBondContact O-ND2 3.1Å; Y181-L193 HydrophobicContact CE2-CD1 4.16Å; Y181-L193 HydrophobicContact CE2-CD2 4.17Å; Y181-E197 VanDerWaalsContact CE1-OE1 3.26Å; Y181-E197 WeakPolarHBondContact CE1-OE1 3.28Å; Y181-E197 VanDerWaalsContact CZ-OE1 3.27Å; Y181-E197 VanDerWaalsContact OH-CD 3.29Å; Y181-E197 PolarHBondContact OH-OE1 3.42Å
182	R	86.3	Confident	85.1	Confident	56 Å²	56	87.7 Å²	87.7	21%	0.211	41%	0.405	C	S	.	.	G	3₁₀ helix	trans	-75.6	-17.4	-178.5	-153.1	177.3	67.5	-151.1	3.3	113.1	H180 N184 F185 N190 L193 L194 E197	H180-R182 WeakPolarHBondContact ND1-CB 3.32Å; H180-R182 PolarHBondContact ND1-N 2.99Å; H180-R182 PolarHBondContact O-N 2.74Å; R182-N184 PolarHBondContact O-N 3.06Å; R182-F185 PolarHBondContact O-N 3.26Å; R182-N190 WeakPolarHBondContact CD-OD1 3.46Å; R182-N190 WeakPolarHBondContact CG-OD1 3.38Å; R182-N190 PolarHBondContact NE-OD1 2.76Å; R182-L193 HydrophobicContact CG-CB 3.94Å; R182-L193 HydrophobicContact CG-CD1 3.84Å; R182-L194 VanDerWaalsContact CZ-CD2 3.41Å; R182-E197 IonicContact NH1-OE2 3.81Å; R182-E197 PolarHBondContact NH1-OE2 2.98Å
183	D	86.4	Confident	85.2	Confident	97 Å²	97	86.9 Å²	86.9	52%	0.519	40%	0.401	S	S	.	.	G	3₁₀ helix	trans	-63.1	-10.8	177.1	-62	-13.6	0	0	0	112.9	R179 H180 Y181	R179-D183 WeakPolarHBondContact CB-OD2 3.42Å; R179-D183 WeakPolarHBondContact CG-OD2 3.42Å; H180-D183 PolarHBondContact N-OD2 3.36Å; H180-D183 WeakPolarHBondContact O-CB 3.39Å; H180-D183 PolarHBondContact O-N 3.11Å; Y181-D183 VanDerWaalsContact C-N 3.32Å
184	N	85.8	Confident	85.3	Confident	65 Å²	65	88.5 Å²	88.5	35%	0.348	41%	0.41	S	S	.	.	G	3₁₀ helix	trans	-84.5	-8	176.1	-58.5	-50	0	0	0	113.8	Q155 Y181 R182	Q155-N184 HydrophobicContact CG-CB 4.2Å; Y181-N184 PolarHBondContact O-ND2 3.1Å; R182-N184 PolarHBondContact O-N 3.06Å
185	F	89.4	Confident	85.6	Confident	15 Å²	15	93.7 Å²	93.7	7%	0.066	43%	0.426	C	S	.	.			trans	-118.6	150.5	-173.8	-59.1	-89.1	0	0	0	110.6	F154 Q155 L157 R160 R182 D189 N190 L193	F154-F185 WeakPolarHBondContact O-CZ 3.46Å; Q155-F185 VanDerWaalsContact O-CE1 3.32Å; Q155-F185 WeakPolarHBondContact O-CE1 3.47Å; L157-F185 HydrophobicContact CB-CD1 4.42Å; L157-F185 HydrophobicContact CB-CE1 3.81Å; L157-F185 HydrophobicContact CD1-CD1 4.15Å; L157-F185 HydrophobicContact CD1-CE1 4.13Å; R160-F185 HydrophobicContact CG-CE2 4.17Å; R160-F185 HydrophobicContact CG-CZ 4.14Å; R182-F185 PolarHBondContact O-N 3.26Å; F185-D189 HydrophobicContact CB-CB 4.06Å; F185-D189 HydrophobicContact CD1-CB 4.02Å; F185-D189 HydrophobicContact CG-CB 4.48Å; F185-N190 HydrophobicContact CB-CB 4.37Å; F185-L193 HydrophobicContact CB-CD1 3.98Å; F185-L193 HydrophobicContact CD1-CD1 4.03Å; F185-L193 HydrophobicContact CD2-CD1 3.29Å; F185-L193 HydrophobicContact CE1-CD1 4.35Å; F185-L193 HydrophobicContact CE2-CD1 3.67Å; F185-L193 HydrophobicContact CG-CD1 3.48Å; F185-L193 VanDerWaalsContact CG-CD1 3.48Å; F185-L193 HydrophobicContact CZ-CD1 4.19Å
186	R	89.1	Confident	86.2	Confident	206 Å²	206	89 Å²	89	78%	0.777	40%	0.396	S	S	*	.			trans	-129.7	160.8	-179.6	-63.7	-175.3	-179	179.5	0.6	110.3	E188 D189 N190	R186-E188 PolarHBondContact O-N 3.25Å; R186-D189 PolarHBondContact O-N 3.07Å; R186-N190 PolarHBondContact O-N 2.87Å
187	D	91.2	Very high	87	Confident	130 Å²	130	89.9 Å²	89.9	70%	0.695	40%	0.402	S	S	*	.	H	α-helix	trans	51.4	-127.3	169.5	-47.1	-43.5	0	0	0	112.6	D189 N190 E191	D187-D189 VanDerWaalsContact C-N 3.31Å; D187-D189 PolarHBondContact O-N 2.68Å; D187-N190 PolarHBondContact O-N 3.15Å; D187-E191 PolarHBondContact O-N 2.81Å; D187-E191 VanDerWaalsContact O-N 3.15Å
188	E	92	Very high	88.6	Confident	148 Å²	148	92.2 Å²	92.2	69%	0.692	41%	0.409	S	S	*	.	H	α-helix	trans	-58.4	-37.2	-176.5	-63.5	-177.1	-179	0	0	113.3	R186 N190 E191 M192	R186-E188 PolarHBondContact O-N 3.25Å; E188-N190 VanDerWaalsContact C-N 3.34Å; E188-N190 PolarHBondContact O-N 2.89Å; E188-E191 WeakPolarHBondContact O-CB 3.45Å; E188-E191 PolarHBondContact O-N 3.16Å; E188-M192 WeakPolarHBondContact O-CG 3.47Å; E188-M192 PolarHBondContact O-N 3.44Å
189	D	91.9	Very high	89.9	Confident	68 Å²	68	83.7 Å²	83.7	36%	0.364	38%	0.38	S	S	.	.	H	α-helix	trans	-64.9	-40.9	179.6	-72.9	-8.4	0	0	0	111.3	L157 F185 R186 D187 E191 M192 L193	L157-D189 HydrophobicContact CD1-CB 4.12Å; L157-D189 HydrophobicContact CD2-CB 4.3Å; L157-D189 WeakPolarHBondContact CD2-OD1 3.49Å; F185-D189 HydrophobicContact CB-CB 4.06Å; F185-D189 HydrophobicContact CD1-CB 4.02Å; F185-D189 HydrophobicContact CG-CB 4.48Å; R186-D189 PolarHBondContact O-N 3.07Å; D187-D189 VanDerWaalsContact C-N 3.31Å; D187-D189 PolarHBondContact O-N 2.68Å; D189-E191 VanDerWaalsContact C-N 3.35Å; D189-M192 PolarHBondContact O-N 3.11Å; D189-L193 WeakPolarHBondContact O-CG 3.29Å; D189-L193 PolarHBondContact O-N 3.35Å
190	N	92.1	Very high	91.2	Very high	43 Å²	43	79.7 Å²	79.7	23%	0.23	37%	0.369	C	S	.	.	H	α-helix	trans	-67.6	-37.4	176.9	176.6	54.9	0	0	0	111	R182 F185 R186 D187 E188 L193 L194	R182-N190 WeakPolarHBondContact CD-OD1 3.46Å; R182-N190 WeakPolarHBondContact CG-OD1 3.38Å; R182-N190 PolarHBondContact NE-OD1 2.76Å; F185-N190 HydrophobicContact CB-CB 4.37Å; R186-N190 PolarHBondContact O-N 2.87Å; D187-N190 PolarHBondContact O-N 3.15Å; E188-N190 VanDerWaalsContact C-N 3.34Å; E188-N190 PolarHBondContact O-N 2.89Å; N190-L193 PolarHBondContact O-N 3.18Å; N190-L194 WeakPolarHBondContact O-CB 3.11Å; N190-L194 WeakPolarHBondContact O-CG 3.49Å; N190-L194 PolarHBondContact O-N 3.13Å
191	E	93.3	Very high	92.2	Very high	116 Å²	116	77.8 Å²	77.8	54%	0.542	36%	0.362	S	S	.	.	H	α-helix	trans	-66.1	-39.2	173.5	-69.1	-177.2	177.9	0	0	112.6	D187 E188 D189 L193 L194 R195	D187-E191 PolarHBondContact O-N 2.81Å; D187-E191 VanDerWaalsContact O-N 3.15Å; E188-E191 WeakPolarHBondContact O-CB 3.45Å; E188-E191 PolarHBondContact O-N 3.16Å; D189-E191 VanDerWaalsContact C-N 3.35Å; E191-L193 VanDerWaalsContact C-N 3.35Å; E191-L194 PolarHBondContact O-N 3.22Å; E191-R195 WeakPolarHBondContact O-CG 3.16Å; E191-R195 PolarHBondContact O-N 3.44Å
192	M	93.8	Very high	92.8	Very high	70 Å²	70	76.9 Å²	76.9	35%	0.345	36%	0.358	S	S	.	.	H	α-helix	trans	-61.4	-43.2	173	-73.5	-179.7	75.5	0	0	111.7	L157 L161 E188 D189 R195 S196	L157-M192 HydrophobicContact CD2-SD 4.18Å; L161-M192 HydrophobicContact CD1-CE 4.05Å; L161-M192 HydrophobicContact CD2-CB 4.37Å; E188-M192 WeakPolarHBondContact O-CG 3.47Å; E188-M192 PolarHBondContact O-N 3.44Å; D189-M192 PolarHBondContact O-N 3.11Å; M192-R195 VanDerWaalsContact CG-NH2 3.3Å; M192-R195 PolarHBondContact O-N 2.85Å; M192-S196 PolarHBondContact O-N 2.95Å
193	L	94.4	Very high	93.4	Very high	0 Å²	0	74.8 Å²	74.8	0%	0	35%	0.351	C	S	.	.	H	α-helix	trans	-65.8	-45.1	176.7	-71.4	171.7	0	0	0	111.8	L157 R160 L161 Y181 R182 F185 D189 N190 E191 R195 S196 E197	L157-L193 HydrophobicContact CD1-CD1 3.95Å; L157-L193 HydrophobicContact CD1-CD2 3.9Å; L157-L193 HydrophobicContact CD1-CG 3.65Å; R160-L193 HydrophobicContact CB-CD2 3.55Å; L161-L193 HydrophobicContact CD2-CD2 3.92Å; L161-L193 HydrophobicContact CG-CD2 4.12Å; Y181-L193 HydrophobicContact CE2-CD1 4.16Å; Y181-L193 HydrophobicContact CE2-CD2 4.17Å; R182-L193 HydrophobicContact CG-CB 3.94Å; R182-L193 HydrophobicContact CG-CD1 3.84Å; F185-L193 HydrophobicContact CB-CD1 3.98Å; F185-L193 HydrophobicContact CD1-CD1 4.03Å; F185-L193 HydrophobicContact CD2-CD1 3.29Å; F185-L193 HydrophobicContact CE1-CD1 4.35Å; F185-L193 HydrophobicContact CE2-CD1 3.67Å; F185-L193 HydrophobicContact CG-CD1 3.48Å; F185-L193 VanDerWaalsContact CG-CD1 3.48Å; F185-L193 HydrophobicContact CZ-CD1 4.19Å; D189-L193 WeakPolarHBondContact O-CG 3.29Å; D189-L193 PolarHBondContact O-N 3.35Å; N190-L193 PolarHBondContact O-N 3.18Å; E191-L193 VanDerWaalsContact C-N 3.35Å; L193-R195 VanDerWaalsContact C-N 3.33Å; L193-R195 PolarHBondContact O-N 3.07Å; L193-S196 WeakPolarHBondContact CA-OG 3.4Å; L193-S196 PolarHBondContact O-N 3.01Å; L193-S196 VanDerWaalsContact O-N 3.15Å; L193-S196 PolarHBondContact O-OG 3.45Å; L193-E197 WeakPolarHBondContact O-CG 3.04Å; L193-E197 PolarHBondContact O-N 3.12Å; L193-E197 VanDerWaalsContact O-N 3.07Å
194	L	93.9	Very high	94	Very high	52 Å²	52	74.5 Å²	74.5	27%	0.272	35%	0.347	S	S	.	.	H	α-helix	trans	-53.8	-49.8	172.9	-88	162.7	0	0	0	111.4	R182 N190 E191 S196 E197 H198	R182-L194 VanDerWaalsContact CZ-CD2 3.41Å; N190-L194 WeakPolarHBondContact O-CB 3.11Å; N190-L194 WeakPolarHBondContact O-CG 3.49Å; N190-L194 PolarHBondContact O-N 3.13Å; E191-L194 PolarHBondContact O-N 3.22Å; L194-S196 VanDerWaalsContact C-N 3.33Å; L194-S196 PolarHBondContact O-N 3.14Å; L194-E197 PolarHBondContact O-N 2.88Å; L194-H198 PolarHBondContact O-N 2.85Å; L194-H198 PolarHBondContact O-ND1 3.35Å
195	R	95	Very high	94.6	Very high	140 Å²	140	71.9 Å²	71.9	53%	0.528	33%	0.333	S	S	.	.	H	α-helix	trans	-57.9	-46	176.4	-75.5	-176	-72	171.4	-6.8	111.7	E191 M192 L193 E197 H198 E199	E191-R195 WeakPolarHBondContact O-CG 3.16Å; E191-R195 PolarHBondContact O-N 3.44Å; M192-R195 VanDerWaalsContact CG-NH2 3.3Å; M192-R195 PolarHBondContact O-N 2.85Å; L193-R195 VanDerWaalsContact C-N 3.33Å; L193-R195 PolarHBondContact O-N 3.07Å; R195-E197 PolarHBondContact O-N 3.36Å; R195-H198 PolarHBondContact O-N 3.46Å; R195-E199 WeakPolarHBondContact O-CG 3.25Å; R195-E199 PolarHBondContact O-N 2.78Å
196	S	96.1	Very high	95	Very high	3 Å²	3	71.2 Å²	71.2	2%	0.021	33%	0.33	C	S	.	.	H	α-helix	trans	-63.4	-23.1	179.7	74.7	0	0	0	0	114.6	N164 M192 L193 L194	N164-S196 WeakPolarHBondContact CB-OG 3.23Å; N164-S196 PolarHBondContact ND2-OG 2.86Å; M192-S196 PolarHBondContact O-N 2.95Å; L193-S196 WeakPolarHBondContact CA-OG 3.4Å; L193-S196 PolarHBondContact O-N 3.01Å; L193-S196 VanDerWaalsContact O-N 3.15Å; L193-S196 PolarHBondContact O-OG 3.45Å; L194-S196 VanDerWaalsContact C-N 3.33Å; L194-S196 PolarHBondContact O-N 3.14Å
197	E	93.1	Very high	95.5	Very high	60 Å²	60	63.5 Å²	63.5	28%	0.28	30%	0.303	S	S	.	.	H	α-helix	trans	-80.9	-27.1	174.5	-70.5	175.9	156.9	0	0	112.8	H180 Y181 R182 L193 L194 R195	H180-E197 IonicContact CE1-OE1 2.84Å; H180-E197 PolarHBondContact CE1-OE1 3.41Å; Y181-E197 VanDerWaalsContact CE1-OE1 3.26Å; Y181-E197 WeakPolarHBondContact CE1-OE1 3.28Å; Y181-E197 VanDerWaalsContact CZ-OE1 3.27Å; Y181-E197 VanDerWaalsContact OH-CD 3.29Å; Y181-E197 PolarHBondContact OH-OE1 3.42Å; R182-E197 IonicContact NH1-OE2 3.81Å; R182-E197 PolarHBondContact NH1-OE2 2.98Å; L193-E197 WeakPolarHBondContact O-CG 3.04Å; L193-E197 PolarHBondContact O-N 3.12Å; L193-E197 VanDerWaalsContact O-N 3.07Å; L194-E197 PolarHBondContact O-N 2.88Å; R195-E197 PolarHBondContact O-N 3.36Å
198	H	93.8	Very high	95.8	Very high	152 Å²	152	59.1 Å²	59.1	70%	0.704	28%	0.284	S	S	*	.	H	α-helix	trans	-95.1	-31.9	-177.6	-68.7	83.8	0	0	0	113.1	L194 R195	L194-H198 PolarHBondContact O-N 2.85Å; L194-H198 PolarHBondContact O-ND1 3.35Å; R195-H198 PolarHBondContact O-N 3.46Å
199	E	95.8	Very high	96.1	Very high	73 Å²	73	53.5 Å²	53.5	34%	0.341	26%	0.257	S	S	.	.	S	Bend	trans	-63.8	152.7	174.8	-70.6	174.3	-164.7	0	0	111.4	R95 K165 R195 T201	R95-E199 IonicContact CZ-OE2 3.76Å; R95-E199 IonicContact NH1-OE2 2.7Å; R95-E199 PolarHBondContact NH1-OE2 3.14Å; R95-E199 VanDerWaalsContact NH2-CB 3.29Å; R95-E199 IonicContact NH2-OE2 3.51Å; R95-E199 PolarHBondContact NH2-OE2 3.44Å; K165-E199 IonicContact NZ-OE2 3.14Å; R195-E199 WeakPolarHBondContact O-CG 3.25Å; R195-E199 PolarHBondContact O-N 2.78Å; E199-T201 PolarHBondContact O-N 3.49Å
200	Q	97.7	Very high	96.4	Very high	100 Å²	100	50.2 Å²	50.2	47%	0.467	24%	0.24	S	C	.	.	P	Polyproline II helix	trans	-61.9	127.3	177	-67.5	-179.6	-47.4	0	0	111.1	R95 L205	R95-Q200 PolarHBondContact NE-O 3.47Å; R95-Q200 PolarHBondContact NH2-O 2.84Å; Q200-L205 HydrophobicContact CB-CD1 4.39Å; Q200-L205 HydrophobicContact CB-CD2 4.06Å; Q200-L205 HydrophobicContact CB-CG 4.07Å
201	T	98.6	Very high	96.7	Very high	18 Å²	18	51.3 Å²	51.3	11%	0.11	24%	0.243	C	C	.	.	P	Polyproline II helix	trans	-78.8	161.5	178	64.2	0	0	0	0	111	N164 E199 L203 Q204 L205	N164-T201 VanDerWaalsContact O-CG2 3.29Å; N164-T201 WeakPolarHBondContact O-CG2 3.37Å; E199-T201 PolarHBondContact O-N 3.49Å; T201-L203 PolarHBondContact O-N 3.31Å; T201-Q204 PolarHBondContact O-N 3.37Å; T201-Q204 WeakPolarHBondContact OG1-CG 3.49Å; T201-Q204 PolarHBondContact OG1-N 2.96Å; T201-Q204 PolarHBondContact OG1-OE1 3.23Å; T201-L205 VanDerWaalsContact O-CG 3.29Å; T201-L205 WeakPolarHBondContact O-CG 3.49Å; T201-L205 PolarHBondContact O-N 3Å
202	L	98.7	Very high	96.9	Very high	3 Å²	3	50.5 Å²	50.5	2%	0.016	24%	0.235	C	C	.	.	H	α-helix	trans	-57.8	-39.9	172.7	-178.6	67.2	0	0	0	111.4	L91 V94 M116 K165 Q204 L205 V206 L315 F363	L91-L202 HydrophobicContact CD1-CB 4.07Å; L91-L202 HydrophobicContact CD1-CD1 4.43Å; L91-L202 HydrophobicContact CD1-CD2 3.71Å; L91-L202 HydrophobicContact CD1-CG 4.29Å; V94-L202 HydrophobicContact CG1-CD1 4.17Å; M116-L202 HydrophobicContact CE-CD2 3.57Å; K165-L202 PolarHBondContact O-N 2.98Å; L202-Q204 PolarHBondContact O-N 3.14Å; L202-L205 PolarHBondContact O-N 2.83Å; L202-V206 HydrophobicContact CD1-CG2 4.02Å; L202-V206 HydrophobicContact CG-CG2 4.17Å; L202-V206 WeakPolarHBondContact O-CB 3.27Å; L202-V206 VanDerWaalsContact O-CG2 3.25Å; L202-V206 WeakPolarHBondContact O-CG2 3.19Å; L202-V206 PolarHBondContact O-N 3.43Å; L202-L315 HydrophobicContact CD2-CD2 3.77Å; L202-L315 HydrophobicContact CG-CD2 4.49Å; L202-F363 HydrophobicContact CD2-CE2 4.34Å; L202-F363 HydrophobicContact CD2-CZ 4.03Å; L202-F363 HydrophobicContact CG-CZ 4.09Å
203	L	98.7	Very high	97.1	Very high	11 Å²	11	47.4 Å²	47.4	6%	0.058	22%	0.22	C	C	.	.	H	α-helix	trans	-54	-53.1	174.6	175.2	64.1	0	0	0	112	I166 T201 L205 V206 E207 R284 L285 V362 F363	I166-L203 PolarHBondContact O-N 3.18Å; I166-L203 VanDerWaalsContact O-N 3.07Å; T201-L203 PolarHBondContact O-N 3.31Å; L203-L205 VanDerWaalsContact C-N 3.32Å; L203-L205 PolarHBondContact O-N 2.91Å; L203-V206 PolarHBondContact O-N 3.22Å; L203-E207 VanDerWaalsContact O-CB 3.3Å; L203-E207 WeakPolarHBondContact O-CB 3.31Å; L203-E207 PolarHBondContact O-N 3.01Å; L203-R284 HydrophobicContact CD1-CB 4.26Å; L203-R284 HydrophobicContact CD2-CB 4Å; L203-L285 HydrophobicContact CD1-CD2 3.69Å; L203-L285 HydrophobicContact CD1-CG 4.43Å; L203-V362 HydrophobicContact CB-CG1 3.73Å; L203-V362 HydrophobicContact CD1-CG1 4.22Å; L203-V362 HydrophobicContact CD2-CG1 3.94Å; L203-V362 HydrophobicContact CG-CG1 4.16Å; L203-F363 HydrophobicContact CB-CE1 4.43Å; L203-F363 HydrophobicContact CD1-CD1 4.05Å; L203-F363 HydrophobicContact CD1-CE1 3.94Å
204	Q	98.6	Very high	97.1	Very high	91 Å²	91	48.4 Å²	48.4	43%	0.425	23%	0.226	S	C	.	.	H	α-helix	trans	-64.5	-36.8	-178.7	-71.8	164.4	-41.3	0	0	112.3	T201 L202 A208	T201-Q204 PolarHBondContact O-N 3.37Å; T201-Q204 WeakPolarHBondContact OG1-CG 3.49Å; T201-Q204 PolarHBondContact OG1-N 2.96Å; T201-Q204 PolarHBondContact OG1-OE1 3.23Å; L202-Q204 PolarHBondContact O-N 3.14Å; Q204-A208 WeakPolarHBondContact O-CB 3.46Å; Q204-A208 PolarHBondContact O-N 3.15Å
205	L	98.7	Very high	97	Very high	10 Å²	10	46.1 Å²	46.1	5%	0.052	22%	0.216	C	C	.	.	H	α-helix	trans	-70	-40.9	178.2	-68.7	169.1	0	0	0	112.1	R95 F98 Q99 Q200 T201 L202 L203 W209	R95-L205 HydrophobicContact CB-CD1 3.75Å; R95-L205 HydrophobicContact CG-CD1 3.92Å; F98-L205 HydrophobicContact CB-CB 3.81Å; F98-L205 HydrophobicContact CB-CD1 4.17Å; F98-L205 HydrophobicContact CB-CD2 4.04Å; F98-L205 HydrophobicContact CB-CG 4.22Å; F98-L205 HydrophobicContact CD1-CB 4.18Å; F98-L205 WeakPolarHBondContact CD1-O 3.5Å; F98-L205 HydrophobicContact CG-CB 4.15Å; Q99-L205 HydrophobicContact CG-CD1 3.85Å; Q99-L205 HydrophobicContact CG-CD2 3.54Å; Q99-L205 HydrophobicContact CG-CG 4.34Å; Q200-L205 HydrophobicContact CB-CD1 4.39Å; Q200-L205 HydrophobicContact CB-CD2 4.06Å; Q200-L205 HydrophobicContact CB-CG 4.07Å; T201-L205 VanDerWaalsContact O-CG 3.29Å; T201-L205 WeakPolarHBondContact O-CG 3.49Å; T201-L205 PolarHBondContact O-N 3Å; L202-L205 PolarHBondContact O-N 2.83Å; L203-L205 VanDerWaalsContact C-N 3.32Å; L203-L205 PolarHBondContact O-N 2.91Å; L205-W209 WeakPolarHBondContact O-CB 3.47Å; L205-W209 PolarHBondContact O-N 3.33Å; L205-W209 VanDerWaalsContact O-N 3.11Å
206	V	98.7	Very high	97	Very high	1 Å²	1	39.7 Å²	39.7	1%	0.006	19%	0.192	C	C	.	.	H	α-helix	trans	-66.9	-42	174	170.2	0	0	0	0	110.6	F98 L202 L203 W209 L210 L315 F363	F98-V206 HydrophobicContact CE1-CG2 4.39Å; F98-V206 HydrophobicContact CZ-CG2 4.44Å; L202-V206 HydrophobicContact CD1-CG2 4.02Å; L202-V206 HydrophobicContact CG-CG2 4.17Å; L202-V206 WeakPolarHBondContact O-CB 3.27Å; L202-V206 VanDerWaalsContact O-CG2 3.25Å; L202-V206 WeakPolarHBondContact O-CG2 3.19Å; L202-V206 PolarHBondContact O-N 3.43Å; L203-V206 PolarHBondContact O-N 3.22Å; V206-W209 HydrophobicContact CG1-CE3 4.38Å; V206-W209 PolarHBondContact O-N 3.34Å; V206-L210 HydrophobicContact CG1-CD1 3.92Å; V206-L210 HydrophobicContact CG1-CG 4.2Å; V206-L210 WeakPolarHBondContact O-CB 3.38Å; V206-L210 WeakPolarHBondContact O-CG 3.48Å; V206-L210 PolarHBondContact O-N 3.28Å; V206-L315 HydrophobicContact CG1-CD1 3.89Å; V206-L315 HydrophobicContact CG2-CD1 3.99Å; V206-F363 HydrophobicContact CB-CE1 4.34Å; V206-F363 HydrophobicContact CG1-CE1 4.36Å; V206-F363 HydrophobicContact CG2-CE1 4.48Å
207	E	98.7	Very high	96.9	Very high	44 Å²	44	43.2 Å²	43.2	21%	0.206	21%	0.208	C	C	.	.	H	α-helix	trans	-54.6	-55.6	173.9	176.3	179.6	-115.5	0	0	111	L203 W209 L210 E211 L285 S286 A289	L203-E207 VanDerWaalsContact O-CB 3.3Å; L203-E207 WeakPolarHBondContact O-CB 3.31Å; L203-E207 PolarHBondContact O-N 3.01Å; E207-W209 PolarHBondContact O-N 3.03Å; E207-L210 WeakPolarHBondContact O-CB 3.16Å; E207-L210 PolarHBondContact O-N 2.95Å; E207-E211 WeakPolarHBondContact O-CG 3.48Å; E207-E211 PolarHBondContact O-N 3.24Å; E207-L285 HydrophobicContact CB-CD2 3.92Å; E207-L285 HydrophobicContact CG-CD2 4.37Å; E207-S286 WeakPolarHBondContact OE1-CB 3.4Å; E207-S286 PolarHBondContact OE1-N 2.93Å; E207-A289 HydrophobicContact CB-CB 4.4Å; E207-A289 HydrophobicContact CG-CB 3.78Å
208	A	98.6	Very high	96.8	Very high	38 Å²	38	44.4 Å²	44.4	31%	0.314	22%	0.221	S	C	.	.	H	α-helix	trans	-59.5	-34.4	179.4	0	0	0	0	0	112.6	Q204 R212	Q204-A208 WeakPolarHBondContact O-CB 3.46Å; Q204-A208 PolarHBondContact O-N 3.15Å; A208-R212 VanDerWaalsContact C-NH1 3.31Å; A208-R212 PolarHBondContact O-NH1 2.94Å
209	W	98.5	Very high	96.6	Very high	30 Å²	30	46.6 Å²	46.6	11%	0.114	23%	0.231	C	C	.	.	H	α-helix	trans	-69.5	-43	174.2	168.9	81.9	0	0	0	112.3	F98 M109 L205 V206 E207 E211 R212 I296 P308 L311 L312	F98-W209 HydrophobicContact CD1-CB 3.95Å; F98-W209 HydrophobicContact CD1-CG 4.43Å; F98-W209 HydrophobicContact CE1-CB 3.63Å; F98-W209 HydrophobicContact CE1-CD2 4.17Å; F98-W209 AromaticContact CE1-CG 3.75Å; F98-W209 HydrophobicContact CE1-CG 3.75Å; M109-W209 HydrophobicContact CE-CH2 4.44Å; M109-W209 HydrophobicContact CE-CZ2 3.81Å; L205-W209 WeakPolarHBondContact O-CB 3.47Å; L205-W209 PolarHBondContact O-N 3.33Å; L205-W209 VanDerWaalsContact O-N 3.11Å; V206-W209 HydrophobicContact CG1-CE3 4.38Å; V206-W209 PolarHBondContact O-N 3.34Å; E207-W209 PolarHBondContact O-N 3.03Å; W209-E211 VanDerWaalsContact C-N 3.32Å; W209-E211 PolarHBondContact O-N 2.68Å; W209-R212 PolarHBondContact O-N 2.68Å; W209-R212 VanDerWaalsContact O-N 3.15Å; W209-I296 HydrophobicContact CH2-CD1 3.78Å; W209-I296 HydrophobicContact CZ3-CD1 4.13Å; W209-P308 HydrophobicContact CH2-CB 3.74Å; W209-P308 HydrophobicContact CH2-CG 4.38Å; W209-P308 HydrophobicContact CZ2-CB 3.91Å; W209-P308 HydrophobicContact CZ2-CG 4.05Å; W209-L311 HydrophobicContact CH2-CD2 4.28Å; W209-L311 HydrophobicContact CZ3-CD2 4.36Å; W209-L312 HydrophobicContact CZ3-CD2 4.25Å
210	L	98.6	Very high	96.4	Very high	0 Å²	0	45.2 Å²	45.2	0%	0	24%	0.237	C	C	.	.	H	α-helix	trans	-62.4	-36.2	177	-76.4	173.2	0	0	0	112.6	V206 E207 R212 T213 L285 A289 A293 I296 L312	V206-L210 HydrophobicContact CG1-CD1 3.92Å; V206-L210 HydrophobicContact CG1-CG 4.2Å; V206-L210 WeakPolarHBondContact O-CB 3.38Å; V206-L210 WeakPolarHBondContact O-CG 3.48Å; V206-L210 PolarHBondContact O-N 3.28Å; E207-L210 WeakPolarHBondContact O-CB 3.16Å; E207-L210 PolarHBondContact O-N 2.95Å; L210-R212 PolarHBondContact O-N 3.25Å; L210-R212 VanDerWaalsContact O-N 3.16Å; L210-T213 VanDerWaalsContact O-CB 3.26Å; L210-T213 WeakPolarHBondContact O-CB 3.25Å; L210-T213 PolarHBondContact O-N 3.25Å; L210-T213 PolarHBondContact O-OG1 3.12Å; L210-L285 HydrophobicContact CD1-CD1 4.07Å; L210-L285 HydrophobicContact CD1-CD2 4.4Å; L210-A289 HydrophobicContact CB-CB 3.84Å; L210-A289 HydrophobicContact CD1-CB 4.32Å; L210-A293 HydrophobicContact CD1-CB 4.13Å; L210-A293 HydrophobicContact CD2-CB 4.12Å; L210-I296 HydrophobicContact CD2-CD1 3.67Å; L210-L312 HydrophobicContact CD2-CD2 4.28Å
211	E	98.4	Very high	96.2	Very high	65 Å²	65	40.6 Å²	40.6	30%	0.304	22%	0.215	S	C	.	.	T	Hydrogen-bonded Turn	trans	-62.8	-20.7	177.2	-70.1	179.9	162.4	0	0	113.8	E207 W209 S286 R288 A289	E207-E211 WeakPolarHBondContact O-CG 3.48Å; E207-E211 PolarHBondContact O-N 3.24Å; W209-E211 VanDerWaalsContact C-N 3.32Å; W209-E211 PolarHBondContact O-N 2.68Å; E211-S286 WeakPolarHBondContact OE1-CB 3.46Å; E211-S286 PolarHBondContact OE1-OG 2.75Å; E211-R288 HydrophobicContact CB-CG 4.23Å; E211-R288 HydrophobicContact CG-CB 4.1Å; E211-R288 HydrophobicContact CG-CG 4.18Å; E211-R288 PolarHBondContact O-NE 3.22Å; E211-A289 HydrophobicContact CG-CB 4.01Å
212	R	96.9	Very high	96	Very high	100 Å²	100	42.3 Å²	42.3	38%	0.377	22%	0.224	S	C	.	.	T	Hydrogen-bonded Turn	trans	-97.1	10.3	176.7	-56.9	-172	-55	-89.6	4.1	113	A208 W209 L210	A208-R212 VanDerWaalsContact C-NH1 3.31Å; A208-R212 PolarHBondContact O-NH1 2.94Å; W209-R212 PolarHBondContact O-N 2.68Å; W209-R212 VanDerWaalsContact O-N 3.15Å; L210-R212 PolarHBondContact O-N 3.25Å; L210-R212 VanDerWaalsContact O-N 3.16Å
213	T	97.1	Very high	95.9	Very high	5 Å²	5	42.2 Å²	42.2	3%	0.031	22%	0.223	C	C	.	.			trans	-58.6	125.6	-180	-59.3	0	0	0	0	109.6	L210 G215 L216 M295 I296 F305	L210-T213 VanDerWaalsContact O-CB 3.26Å; L210-T213 WeakPolarHBondContact O-CB 3.25Å; L210-T213 PolarHBondContact O-N 3.25Å; L210-T213 PolarHBondContact O-OG1 3.12Å; T213-G215 PolarHBondContact O-N 3.02Å; T213-L216 WeakPolarHBondContact O-CG 3.42Å; T213-M295 HydrophobicContact CG2-CB 4.14Å; T213-M295 HydrophobicContact CG2-CG 3.96Å; T213-I296 HydrophobicContact CG2-CD1 4.32Å; T213-I296 HydrophobicContact CG2-CG1 4.01Å; T213-F305 HydrophobicContact CG2-CE1 3.8Å; T213-F305 HydrophobicContact CG2-CZ 4.02Å
214	P	94.4	Very high	95.9	Very high	20 Å²	20	43 Å²	43	13%	0.13	23%	0.225	C	C	.	.	T	Hydrogen-bonded Turn	trans	-62.3	137.4	-179	20.6	-30.2	0	0	0	111.5	F305 F389 L390	P214-F305 HydrophobicContact CG-CE1 3.83Å; P214-F305 HydrophobicContact CG-CZ 3.85Å; P214-F389 HydrophobicContact CB-CD1 4.4Å; P214-F389 HydrophobicContact CB-CE1 3.52Å; P214-F389 HydrophobicContact CB-CZ 4.27Å; P214-L390 HydrophobicContact CB-CD2 4.41Å; P214-L390 HydrophobicContact CG-CD2 4.11Å
215	G	92.9	Very high	95.8	Very high	5 Å²	5	40 Å²	40	5%	0.052	22%	0.218	C	C	.	.	T	Hydrogen-bonded Turn	trans	104.4	-6.1	177.9	0	0	0	0	0	114.6	T213 E217 N222 F223	T213-G215 PolarHBondContact O-N 3.02Å; G215-E217 VanDerWaalsContact C-N 3.3Å; G215-E217 VanDerWaalsContact CA-OE2 3.27Å; G215-E217 WeakPolarHBondContact CA-OE2 3.49Å; G215-E217 PolarHBondContact N-OE2 2.87Å; G215-N222 PolarHBondContact O-N 3.25Å; G215-F223 WeakPolarHBondContact O-CB 3.32Å; G215-F223 PolarHBondContact O-N 3.2Å
216	L	95.3	Very high	95.7	Very high	5 Å²	5	43 Å²	43	3%	0.026	23%	0.231	C	C	.	.			trans	-79.5	-12.6	173.4	-60.3	-175.6	0	0	0	113.1	T213 P218 F223 R288 Q291 M295	T213-L216 WeakPolarHBondContact O-CG 3.42Å; L216-P218 WeakPolarHBondContact O-CD 3.42Å; L216-F223 HydrophobicContact CD2-CB 4.37Å; L216-F223 HydrophobicContact CD2-CD1 3.87Å; L216-R288 HydrophobicContact CD1-CG 4.29Å; L216-Q291 HydrophobicContact CD1-CB 4.35Å; L216-Q291 HydrophobicContact CD2-CB 3.8Å; L216-M295 HydrophobicContact CD2-CB 4.31Å
217	E	93.8	Very high	95.7	Very high	76 Å²	76	42.9 Å²	42.9	36%	0.355	23%	0.23	S	C	.	.			trans	-65.9	126.7	-175.1	-57.8	77.3	-166.4	0	0	111	G215 H219 G220 N222	G215-E217 VanDerWaalsContact C-N 3.3Å; G215-E217 VanDerWaalsContact CA-OE2 3.27Å; G215-E217 WeakPolarHBondContact CA-OE2 3.49Å; G215-E217 PolarHBondContact N-OE2 2.87Å; E217-H219 VanDerWaalsContact C-N 3.26Å; E217-H219 PolarHBondContact O-N 3.46Å; E217-G220 PolarHBondContact O-N 2.96Å; E217-N222 WeakPolarHBondContact O-CA 3.4Å; E217-N222 PolarHBondContact O-N 2.92Å
218	P	91.2	Very high	95.6	Very high	86 Å²	86	44.5 Å²	44.5	56%	0.558	24%	0.238	S	C	*	.	T	Hydrogen-bonded Turn	trans	-60.9	-33.3	-179.9	-26	34.7	0	0	0	113.8	L216	L216-P218 WeakPolarHBondContact O-CD 3.42Å
219	H	89.8	Confident	95.6	Very high	197 Å²	197	48.9 Å²	48.9	91%	0.912	25%	0.252	S	S	*	.	T	Hydrogen-bonded Turn	trans	-90.7	-0.1	176.6	-55.5	-56.1	0	0	0	113.2	E217	E217-H219 VanDerWaalsContact C-N 3.26Å; E217-H219 PolarHBondContact O-N 3.46Å
220	G	90.6	Very high	95.5	Very high	44 Å²	44	49.5 Å²	49.5	45%	0.454	26%	0.257	S	S	.	.	T	Hydrogen-bonded Turn	trans	-104.5	-124.4	178.1	0	0	0	0	0	111.5	E217 N222	E217-G220 PolarHBondContact O-N 2.96Å; G220-N222 VanDerWaalsContact C-N 3.26Å; G220-N222 PolarHBondContact O-N 2.92Å
221	F	93	Very high	95.5	Very high	3 Å²	3	49.5 Å²	49.5	1%	0.013	26%	0.257	C	S	.	.	T	Hydrogen-bonded Turn	trans	-67.3	-28.4	176.8	179.5	-120.4	0	0	0	112.5	F223 K226 M295 Y299 P380 M382 I386	F221-F223 HydrophobicContact CD1-CB 3.83Å; F221-F223 HydrophobicContact CE1-CB 3.98Å; F221-F223 HydrophobicContact CE1-CD2 4.23Å; F221-K226 WeakPolarHBondContact O-CD 3.37Å; F221-K226 WeakPolarHBondContact O-CE 3.32Å; F221-K226 PolarHBondContact O-NZ 3.25Å; F221-M295 HydrophobicContact CD1-CE 3.88Å; F221-M295 HydrophobicContact CD1-SD 4.38Å; F221-M295 HydrophobicContact CE1-CE 3.94Å; F221-M295 HydrophobicContact CE1-SD 4.25Å; F221-Y299 HydrophobicContact CE1-CE2 4.21Å; F221-P380 HydrophobicContact CZ-CB 4.04Å; F221-M382 HydrophobicContact CD2-SD 4.31Å; F221-M382 HydrophobicContact CE1-CE 4.11Å; F221-M382 HydrophobicContact CE1-SD 4.18Å; F221-M382 HydrophobicContact CE2-SD 3.82Å; F221-M382 HydrophobicContact CZ-CE 4.17Å; F221-M382 HydrophobicContact CZ-SD 3.74Å; F221-I386 HydrophobicContact CB-CD1 4.05Å; F221-I386 HydrophobicContact CB-CG1 4.22Å; F221-I386 HydrophobicContact CB-CG2 4.37Å; F221-I386 HydrophobicContact CD2-CB 4.38Å; F221-I386 HydrophobicContact CD2-CG1 4Å; F221-I386 HydrophobicContact CD2-CG2 4.1Å; F221-I386 HydrophobicContact CG-CG1 4.47Å; F221-I386 HydrophobicContact CG-CG2 4.25Å
222	N	95.8	Very high	95.4	Very high	55 Å²	55	50.4 Å²	50.4	29%	0.294	26%	0.264	S	S	.	.			trans	49.9	57.5	-175.7	-172.5	19.6	0	0	0	112.3	G215 E217 G220 W224 G225 K226	G215-N222 PolarHBondContact O-N 3.25Å; E217-N222 WeakPolarHBondContact O-CA 3.4Å; E217-N222 PolarHBondContact O-N 2.92Å; G220-N222 VanDerWaalsContact C-N 3.26Å; G220-N222 PolarHBondContact O-N 2.92Å; N222-W224 VanDerWaalsContact C-N 3.27Å; N222-W224 PolarHBondContact O-N 3.39Å; N222-G225 PolarHBondContact OD1-N 3.37Å; N222-K226 WeakPolarHBondContact O-CG 3.48Å; N222-K226 PolarHBondContact O-N 3.47Å
223	F	96.7	Very high	95.4	Very high	0 Å²	0	51.5 Å²	51.5	0%	0	27%	0.271	C	S	.	.	H	α-helix	trans	-51.1	-48.6	179.6	167.1	-118	0	0	0	111.8	G215 L216 F221 K226 F227 L294 M295 F298 Y299 P380	G215-F223 WeakPolarHBondContact O-CB 3.32Å; G215-F223 PolarHBondContact O-N 3.2Å; L216-F223 HydrophobicContact CD2-CB 4.37Å; L216-F223 HydrophobicContact CD2-CD1 3.87Å; F221-F223 HydrophobicContact CD1-CB 3.83Å; F221-F223 HydrophobicContact CE1-CB 3.98Å; F221-F223 HydrophobicContact CE1-CD2 4.23Å; F223-K226 PolarHBondContact O-N 2.98Å; F223-F227 HydrophobicContact CD2-CB 4.4Å; F223-F227 HydrophobicContact CE2-CB 4.05Å; F223-F227 HydrophobicContact CE2-CD2 4.4Å; F223-F227 HydrophobicContact CE2-CG 4.14Å; F223-F227 HydrophobicContact CZ-CB 4.31Å; F223-F227 HydrophobicContact CZ-CD1 4.2Å; F223-F227 HydrophobicContact CZ-CG 4.13Å; F223-F227 WeakPolarHBondContact O-CB 3.3Å; F223-F227 PolarHBondContact O-N 3.46Å; F223-L294 HydrophobicContact CE1-CB 4.39Å; F223-L294 HydrophobicContact CE1-CD2 4.49Å; F223-L294 HydrophobicContact CZ-CD2 4.28Å; F223-L294 HydrophobicContact CZ-CG 4.29Å; F223-M295 HydrophobicContact CB-SD 3.67Å; F223-M295 HydrophobicContact CD1-CB 4.09Å; F223-M295 HydrophobicContact CD1-SD 4.01Å; F223-M295 HydrophobicContact CD2-SD 3.71Å; F223-M295 HydrophobicContact CE1-CB 4.19Å; F223-M295 HydrophobicContact CE2-SD 4.38Å; F223-M295 HydrophobicContact CG-SD 3.5Å; F223-M295 WeakPolarHBondContact CG-SD 3.4Å; F223-F298 AromaticContact CE2-CD2 3.98Å; F223-F298 HydrophobicContact CE2-CD2 3.98Å; F223-F298 AromaticContact CZ-CD2 3.76Å; F223-F298 HydrophobicContact CZ-CD2 3.76Å; F223-F298 HydrophobicContact CZ-CE2 4.12Å; F223-Y299 AromaticContact CD2-CE2 3.85Å; F223-Y299 HydrophobicContact CD2-CE2 3.85Å; F223-Y299 AromaticContact CE2-CE2 3.92Å; F223-Y299 HydrophobicContact CE2-CE2 3.92Å; F223-P380 HydrophobicContact CD2-CG 4.39Å
224	W	97.4	Very high	95.4	Very high	29 Å²	29	51.3 Å²	51.3	11%	0.11	27%	0.271	C	S	.	.	H	α-helix	trans	-65.2	-49.2	-171.7	-158.9	-115.7	0	0	0	113.1	N222 K226 F227 E228 L268 F269 Y287 Q291 L294	N222-W224 VanDerWaalsContact C-N 3.27Å; N222-W224 PolarHBondContact O-N 3.39Å; W224-K226 PolarHBondContact O-N 2.83Å; W224-F227 HydrophobicContact CE3-CD1 4.45Å; W224-F227 HydrophobicContact CZ3-CD1 4.33Å; W224-F227 PolarHBondContact O-N 3.32Å; W224-E228 PolarHBondContact O-N 3.21Å; W224-L268 HydrophobicContact CH2-CD1 3.87Å; W224-L268 HydrophobicContact CH2-CD2 3.78Å; W224-L268 HydrophobicContact CH2-CG 3.53Å; W224-L268 HydrophobicContact CZ2-CG 3.97Å; W224-L268 HydrophobicContact CZ3-CD2 4.33Å; W224-F269 HydrophobicContact CD2-CD1 4.31Å; W224-F269 HydrophobicContact CD2-CE1 4.09Å; W224-F269 AromaticContact CE2-CD1 3.57Å; W224-F269 AromaticContact CE2-CE1 3.75Å; W224-F269 HydrophobicContact CE3-CE1 4.47Å; W224-F269 HydrophobicContact CH2-CE1 4.37Å; W224-F269 AromaticContact CZ2-CD1 3.73Å; W224-F269 HydrophobicContact CZ2-CD1 3.73Å; W224-F269 AromaticContact CZ2-CE1 3.91Å; W224-F269 HydrophobicContact CZ2-CE1 3.91Å; W224-F269 AromaticContact NE1-CD1 3.53Å; W224-Y287 AromaticContact CE2-CZ 3.88Å; W224-Y287 AromaticContact CZ2-CE2 3.87Å; W224-Y287 HydrophobicContact CZ2-CE2 3.87Å; W224-Y287 AromaticContact CZ2-CZ 3.63Å; W224-Y287 VanDerWaalsContact CZ2-OH 3.27Å; W224-Y287 WeakPolarHBondContact CZ2-OH 3.27Å; W224-Y287 AromaticContact NE1-CZ 3.72Å; W224-Y287 PolarHBondContact NE1-OH 3.39Å; W224-Y287 VanDerWaalsContact NE1-OH 3.07Å; W224-Q291 HydrophobicContact CD2-CG 3.67Å; W224-Q291 HydrophobicContact CE3-CB 4.03Å; W224-Q291 HydrophobicContact CE3-CG 3.53Å; W224-Q291 HydrophobicContact CG-CG 4.31Å; W224-Q291 HydrophobicContact CH2-CG 3.93Å; W224-Q291 HydrophobicContact CZ2-CG 4.11Å; W224-Q291 HydrophobicContact CZ3-CB 4.17Å; W224-Q291 HydrophobicContact CZ3-CG 3.66Å; W224-L294 HydrophobicContact CZ3-CD2 4.06Å
225	G	96.8	Very high	95.5	Very high	26 Å²	26	50.6 Å²	50.6	27%	0.268	27%	0.265	S	S	.	.	H	α-helix	trans	-63.8	-40.8	179	0	0	0	0	0	112.8	N222 F227 E228 E229	N222-G225 PolarHBondContact OD1-N 3.37Å; G225-F227 VanDerWaalsContact C-N 3.33Å; G225-F227 PolarHBondContact O-N 3.35Å; G225-E228 PolarHBondContact O-N 3.38Å; G225-E229 PolarHBondContact O-N 3.4Å; G225-E229 VanDerWaalsContact O-N 3.08Å
226	K	96.9	Very high	95.7	Very high	73 Å²	73	56.3 Å²	56.3	32%	0.317	29%	0.291	S	S	.	.	H	α-helix	trans	-67.6	-34.6	175.8	-70.1	177	179.1	164.8	0	112.6	F221 N222 F223 W224 N230 P380	F221-K226 WeakPolarHBondContact O-CD 3.37Å; F221-K226 WeakPolarHBondContact O-CE 3.32Å; F221-K226 PolarHBondContact O-NZ 3.25Å; N222-K226 WeakPolarHBondContact O-CG 3.48Å; N222-K226 PolarHBondContact O-N 3.47Å; F223-K226 PolarHBondContact O-N 2.98Å; W224-K226 PolarHBondContact O-N 2.83Å; K226-N230 WeakPolarHBondContact O-CB 3.38Å; K226-N230 VanDerWaalsContact O-CG 3.3Å; K226-N230 PolarHBondContact O-N 3.33Å; K226-P380 HydrophobicContact CB-CB 3.87Å; K226-P380 HydrophobicContact CB-CG 3.79Å; K226-P380 HydrophobicContact CD-CB 4.41Å
227	F	97.5	Very high	95.7	Very high	0 Å²	0	60.7 Å²	60.7	0%	0	31%	0.311	C	S	.	.	H	α-helix	trans	-69	-41.7	178.9	-173.7	-127.5	0	0	0	111.2	F223 W224 G225 N230 I231 L268 F269 L294 F298 V374 P380	F223-F227 HydrophobicContact CD2-CB 4.4Å; F223-F227 HydrophobicContact CE2-CB 4.05Å; F223-F227 HydrophobicContact CE2-CD2 4.4Å; F223-F227 HydrophobicContact CE2-CG 4.14Å; F223-F227 HydrophobicContact CZ-CB 4.31Å; F223-F227 HydrophobicContact CZ-CD1 4.2Å; F223-F227 HydrophobicContact CZ-CG 4.13Å; F223-F227 WeakPolarHBondContact O-CB 3.3Å; F223-F227 PolarHBondContact O-N 3.46Å; W224-F227 HydrophobicContact CE3-CD1 4.45Å; W224-F227 HydrophobicContact CZ3-CD1 4.33Å; W224-F227 PolarHBondContact O-N 3.32Å; G225-F227 VanDerWaalsContact C-N 3.33Å; G225-F227 PolarHBondContact O-N 3.35Å; F227-N230 PolarHBondContact O-N 3.22Å; F227-I231 HydrophobicContact CD1-CD1 3.99Å; F227-I231 HydrophobicContact CD2-CD1 4.21Å; F227-I231 HydrophobicContact CD2-CG1 4.47Å; F227-I231 HydrophobicContact CE1-CD1 3.47Å; F227-I231 VanDerWaalsContact CE1-CD1 3.47Å; F227-I231 HydrophobicContact CE2-CD1 3.75Å; F227-I231 HydrophobicContact CE2-CG1 4.16Å; F227-I231 HydrophobicContact CG-CD1 4.33Å; F227-I231 HydrophobicContact CZ-CD1 3.35Å; F227-I231 HydrophobicContact CZ-CG1 4.23Å; F227-I231 WeakPolarHBondContact O-CB 3.44Å; F227-I231 WeakPolarHBondContact O-CG1 3.5Å; F227-I231 PolarHBondContact O-N 3.36Å; F227-L268 HydrophobicContact CD1-CD2 4.47Å; F227-L268 HydrophobicContact CE1-CD2 3.78Å; F227-F269 HydrophobicContact CD1-CE1 4.11Å; F227-F269 AromaticContact CD1-CZ 3.76Å; F227-F269 HydrophobicContact CD1-CZ 3.76Å; F227-F269 HydrophobicContact CE1-CZ 4.21Å; F227-F269 HydrophobicContact CG-CZ 4.46Å; F227-L294 HydrophobicContact CD1-CD2 4.23Å; F227-L294 HydrophobicContact CE1-CD2 3.59Å; F227-L294 HydrophobicContact CZ-CD2 4.19Å; F227-F298 HydrophobicContact CD2-CE2 4.29Å; F227-F298 AromaticContact CE1-CE2 3.99Å; F227-F298 HydrophobicContact CE1-CE2 3.99Å; F227-F298 HydrophobicContact CE2-CD2 4.38Å; F227-F298 AromaticContact CE2-CE2 3.52Å; F227-F298 HydrophobicContact CE2-CE2 3.52Å; F227-F298 AromaticContact CE2-CZ 3.91Å; F227-F298 HydrophobicContact CE2-CZ 3.91Å; F227-F298 AromaticContact CZ-CE2 3.34Å; F227-F298 HydrophobicContact CZ-CE2 3.34Å; F227-F298 AromaticContact CZ-CZ 3.62Å; F227-F298 HydrophobicContact CZ-CZ 3.62Å; F227-V374 HydrophobicContact CE2-CG2 3.66Å; F227-V374 HydrophobicContact CZ-CG1 4.38Å; F227-V374 HydrophobicContact CZ-CG2 4.08Å; F227-P380 HydrophobicContact CB-CG 4.05Å; F227-P380 HydrophobicContact CD2-CG 4.43Å
228	E	97.7	Very high	95.8	Very high	78 Å²	78	59.5 Å²	59.5	36%	0.364	31%	0.306	S	S	.	.	H	α-helix	trans	-59.3	-50.1	172.8	-170.3	174.5	-169.3	0	0	111.8	W224 G225 N230 I231 L232 F269	W224-E228 PolarHBondContact O-N 3.21Å; G225-E228 PolarHBondContact O-N 3.38Å; E228-N230 VanDerWaalsContact C-N 3.34Å; E228-N230 PolarHBondContact O-N 3.36Å; E228-I231 PolarHBondContact O-N 2.79Å; E228-L232 HydrophobicContact CG-CD1 4.14Å; E228-L232 WeakPolarHBondContact O-CG 3.22Å; E228-L232 PolarHBondContact O-N 3.03Å; E228-F269 HydrophobicContact CB-CD1 3.77Å; E228-F269 HydrophobicContact CB-CE1 3.48Å; E228-F269 VanDerWaalsContact CB-CE1 3.48Å; E228-F269 HydrophobicContact CB-CE2 4.28Å; E228-F269 HydrophobicContact CB-CG 4.31Å; E228-F269 HydrophobicContact CB-CZ 3.76Å; E228-F269 HydrophobicContact CG-CD1 3.85Å; E228-F269 HydrophobicContact CG-CD2 4.07Å; E228-F269 HydrophobicContact CG-CE1 4Å; E228-F269 HydrophobicContact CG-CE2 4.19Å; E228-F269 HydrophobicContact CG-CG 3.9Å; E228-F269 HydrophobicContact CG-CZ 4.16Å
229	E	97.4	Very high	96	Very high	129 Å²	129	58.8 Å²	58.8	60%	0.603	29%	0.294	S	S	*	.	H	α-helix	trans	-57.1	-46.5	178	-174.1	-176.7	175.1	0	0	111.7	G225 L232 K233	G225-E229 PolarHBondContact O-N 3.4Å; G225-E229 VanDerWaalsContact O-N 3.08Å; E229-L232 PolarHBondContact O-N 3.26Å; E229-K233 WeakPolarHBondContact O-CB 3.35Å; E229-K233 PolarHBondContact O-N 3.42Å
230	N	97.8	Very high	96.3	Very high	44 Å²	44	53.9 Å²	53.9	24%	0.235	27%	0.274	C	S	.	.	H	α-helix	trans	-67.1	-37.2	179.2	-77	1.5	0	0	0	113	K226 F227 E228 G234 W378	K226-N230 WeakPolarHBondContact O-CB 3.38Å; K226-N230 VanDerWaalsContact O-CG 3.3Å; K226-N230 PolarHBondContact O-N 3.33Å; F227-N230 PolarHBondContact O-N 3.22Å; E228-N230 VanDerWaalsContact C-N 3.34Å; E228-N230 PolarHBondContact O-N 3.36Å; N230-G234 PolarHBondContact O-N 3.41Å; N230-W378 WeakPolarHBondContact CB-O 3.43Å; N230-W378 PolarHBondContact ND2-O 2.86Å
231	I	97.3	Very high	96.5	Very high	0 Å²	0	58.4 Å²	58.4	0%	0	28%	0.277	C	S	.	.	H	α-helix	trans	-65.2	-46.4	175.5	-81.3	174.9	0	0	0	110.3	F227 E228 K233 G234 L235 L265 L266 F269 V374 W378	F227-I231 HydrophobicContact CD1-CD1 3.99Å; F227-I231 HydrophobicContact CD2-CD1 4.21Å; F227-I231 HydrophobicContact CD2-CG1 4.47Å; F227-I231 HydrophobicContact CE1-CD1 3.47Å; F227-I231 VanDerWaalsContact CE1-CD1 3.47Å; F227-I231 HydrophobicContact CE2-CD1 3.75Å; F227-I231 HydrophobicContact CE2-CG1 4.16Å; F227-I231 HydrophobicContact CG-CD1 4.33Å; F227-I231 HydrophobicContact CZ-CD1 3.35Å; F227-I231 HydrophobicContact CZ-CG1 4.23Å; F227-I231 WeakPolarHBondContact O-CB 3.44Å; F227-I231 WeakPolarHBondContact O-CG1 3.5Å; F227-I231 PolarHBondContact O-N 3.36Å; E228-I231 PolarHBondContact O-N 2.79Å; I231-K233 VanDerWaalsContact C-N 3.33Å; I231-K233 PolarHBondContact O-N 3.46Å; I231-G234 PolarHBondContact O-N 2.96Å; I231-L235 HydrophobicContact CG2-CD1 3.61Å; I231-L235 HydrophobicContact CG2-CG 4.24Å; I231-L235 WeakPolarHBondContact O-CB 3.36Å; I231-L235 VanDerWaalsContact O-CG 3.23Å; I231-L235 WeakPolarHBondContact O-CG 3.45Å; I231-L235 PolarHBondContact O-N 3.2Å; I231-L265 HydrophobicContact CG2-CB 4.29Å; I231-L266 HydrophobicContact CG2-CD2 4.39Å; I231-F269 HydrophobicContact CB-CE2 4.36Å; I231-F269 HydrophobicContact CD1-CE2 3.82Å; I231-F269 HydrophobicContact CD1-CZ 3.8Å; I231-F269 HydrophobicContact CG2-CE2 4.29Å; I231-V374 HydrophobicContact CD1-CG1 4.05Å; I231-V374 HydrophobicContact CG1-CG1 4.12Å; I231-W378 HydrophobicContact CG1-CE3 4.3Å
232	L	97.4	Very high	96.6	Very high	84 Å²	84	58.7 Å²	58.7	44%	0.44	28%	0.279	S	S	.	.	H	α-helix	trans	-59	-46.8	178.8	-73	169.9	0	0	0	111.1	E228 E229 L235 E236 L266	E228-L232 HydrophobicContact CG-CD1 4.14Å; E228-L232 WeakPolarHBondContact O-CG 3.22Å; E228-L232 PolarHBondContact O-N 3.03Å; E229-L232 PolarHBondContact O-N 3.26Å; L232-L235 PolarHBondContact O-N 2.83Å; L232-E236 PolarHBondContact O-N 2.92Å; L232-L266 HydrophobicContact CD2-CD2 3.64Å; L232-L266 HydrophobicContact CG-CD2 4.45Å
233	K	97.3	Very high	96.6	Very high	122 Å²	122	60.8 Å²	60.8	53%	0.53	29%	0.287	S	S	.	.	H	α-helix	trans	-63.1	-46.6	176.3	-176.1	179	176.4	-179	0	112.4	E229 I231 L235 E236 E237	E229-K233 WeakPolarHBondContact O-CB 3.35Å; E229-K233 PolarHBondContact O-N 3.42Å; I231-K233 VanDerWaalsContact C-N 3.33Å; I231-K233 PolarHBondContact O-N 3.46Å; K233-L235 VanDerWaalsContact C-N 3.34Å; K233-L235 PolarHBondContact O-N 3.43Å; K233-E236 WeakPolarHBondContact O-CB 3.44Å; K233-E236 PolarHBondContact O-N 3.3Å; K233-E237 WeakPolarHBondContact CE-OE1 3.49Å; K233-E237 WeakPolarHBondContact O-CG 3.5Å; K233-E237 PolarHBondContact O-N 3.5Å
234	G	96.7	Very high	96.5	Very high	2 Å²	2	65.1 Å²	65.1	2%	0.021	32%	0.322	C	S	.	.	H	α-helix	trans	-62.1	-40.8	179.6	0	0	0	0	0	112.7	N230 I231 E237 E238 W378	N230-G234 PolarHBondContact O-N 3.41Å; I231-G234 PolarHBondContact O-N 2.96Å; G234-E237 PolarHBondContact O-N 3.45Å; G234-E238 WeakPolarHBondContact O-CB 3.43Å; G234-E238 WeakPolarHBondContact O-CG 3.26Å; G234-E238 PolarHBondContact O-N 3.4Å; G234-W378 VanDerWaalsContact CA-CE2 3.47Å; G234-W378 VanDerWaalsContact CA-CZ2 3.41Å; G234-W378 VanDerWaalsContact O-CZ2 3.26Å; G234-W378 WeakPolarHBondContact O-CZ2 3.38Å
235	L	96.4	Very high	96.4	Very high	4 Å²	4	66.9 Å²	66.9	2%	0.021	33%	0.331	C	S	.	.	H	α-helix	trans	-64.8	-38.4	174.6	-72.8	169.7	0	0	0	112.1	I231 L232 K233 E238 F239 Y258 K262 L265 L266 W378	I231-L235 HydrophobicContact CG2-CD1 3.61Å; I231-L235 HydrophobicContact CG2-CG 4.24Å; I231-L235 WeakPolarHBondContact O-CB 3.36Å; I231-L235 VanDerWaalsContact O-CG 3.23Å; I231-L235 WeakPolarHBondContact O-CG 3.45Å; I231-L235 PolarHBondContact O-N 3.2Å; L232-L235 PolarHBondContact O-N 2.83Å; K233-L235 VanDerWaalsContact C-N 3.34Å; K233-L235 PolarHBondContact O-N 3.43Å; L235-E238 PolarHBondContact O-N 3.45Å; L235-F239 WeakPolarHBondContact O-CB 3.48Å; L235-F239 PolarHBondContact O-N 2.95Å; L235-Y258 HydrophobicContact CB-CE2 4.15Å; L235-Y258 HydrophobicContact CD2-CD2 4.37Å; L235-Y258 HydrophobicContact CD2-CE2 3.76Å; L235-Y258 VanDerWaalsContact O-CE2 3.24Å; L235-Y258 WeakPolarHBondContact O-CE2 3.25Å; L235-Y258 PolarHBondContact O-OH 3.1Å; L235-Y258 VanDerWaalsContact O-OH 3.1Å; L235-K262 HydrophobicContact CD1-CB 4.38Å; L235-K262 HydrophobicContact CD1-CG 4.16Å; L235-K262 HydrophobicContact CD2-CB 4.18Å; L235-L265 HydrophobicContact CD2-CD1 4.25Å; L235-L266 HydrophobicContact CD1-CD2 4.23Å; L235-L266 HydrophobicContact CD1-CG 4.32Å; L235-W378 HydrophobicContact CD2-CH2 4.25Å; L235-W378 HydrophobicContact CD2-CZ3 4.34Å; L235-W378 HydrophobicContact CG-CH2 4.29Å; L235-W378 HydrophobicContact CG-CZ3 4.19Å
236	E	96.6	Very high	96.3	Very high	126 Å²	126	74.6 Å²	74.6	59%	0.589	36%	0.357	S	S	*	.	H	α-helix	trans	-64.7	-45.5	174.9	-173.3	174.6	-165.3	0	0	111.9	L232 K233 E238 F239 L240	L232-E236 PolarHBondContact O-N 2.92Å; K233-E236 WeakPolarHBondContact O-CB 3.44Å; K233-E236 PolarHBondContact O-N 3.3Å; E236-E238 VanDerWaalsContact C-N 3.35Å; E236-E238 PolarHBondContact O-N 3.24Å; E236-F239 WeakPolarHBondContact O-CB 3.42Å; E236-F239 PolarHBondContact O-N 2.88Å; E236-L240 WeakPolarHBondContact O-CG 3.37Å; E236-L240 PolarHBondContact O-N 3.41Å
237	E	95.7	Very high	96.2	Very high	96 Å²	96	78.2 Å²	78.2	45%	0.449	38%	0.375	S	S	.	.	H	α-helix	trans	-60.6	-43.2	175.6	-71.3	176.3	-175.1	0	0	111.8	K233 G234 L240 R241	K233-E237 WeakPolarHBondContact CE-OE1 3.49Å; K233-E237 WeakPolarHBondContact O-CG 3.5Å; K233-E237 PolarHBondContact O-N 3.5Å; G234-E237 PolarHBondContact O-N 3.45Å; E237-L240 PolarHBondContact O-N 3.48Å; E237-R241 WeakPolarHBondContact O-CB 3.47Å; E237-R241 PolarHBondContact O-N 3.42Å
238	E	95.3	Very high	96.1	Very high	51 Å²	51	80.7 Å²	80.7	24%	0.238	39%	0.393	C	S	.	.	H	α-helix	trans	-64.3	-40.8	175.7	-77.8	-63.3	147.1	0	0	112.5	G234 L235 E236 R241 I242 Y258 W378	G234-E238 WeakPolarHBondContact O-CB 3.43Å; G234-E238 WeakPolarHBondContact O-CG 3.26Å; G234-E238 PolarHBondContact O-N 3.4Å; L235-E238 PolarHBondContact O-N 3.45Å; E236-E238 VanDerWaalsContact C-N 3.35Å; E236-E238 PolarHBondContact O-N 3.24Å; E238-R241 WeakPolarHBondContact O-CB 3.46Å; E238-R241 PolarHBondContact O-N 2.97Å; E238-R241 IonicContact OE1-CZ 3.24Å; E238-R241 IonicContact OE1-NE 3.91Å; E238-R241 PolarHBondContact OE1-NE 3.33Å; E238-R241 IonicContact OE1-NH2 3.67Å; E238-R241 IonicContact OE2-CZ 3.41Å; E238-R241 IonicContact OE2-NE 2.68Å; E238-R241 PolarHBondContact OE2-NE 3.21Å; E238-R241 IonicContact OE2-NH2 2.68Å; E238-R241 PolarHBondContact OE2-NH2 2.82Å; E238-I242 WeakPolarHBondContact O-CG1 3.3Å; E238-I242 PolarHBondContact O-N 3.23Å; E238-Y258 HydrophobicContact CB-CD2 4.42Å; E238-Y258 HydrophobicContact CB-CE2 4.4Å; E238-W378 HydrophobicContact CG-CH2 4.06Å; E238-W378 HydrophobicContact CG-CZ2 3.71Å
239	F	96.3	Very high	96	Very high	72 Å²	72	84.1 Å²	84.1	32%	0.316	41%	0.409	S	S	.	.	H	α-helix	trans	-59.6	-49	174.9	176.3	-101.7	0	0	0	111.6	L235 E236 R241 I242 Q243 M255 Y258	L235-F239 WeakPolarHBondContact O-CB 3.48Å; L235-F239 PolarHBondContact O-N 2.95Å; E236-F239 WeakPolarHBondContact O-CB 3.42Å; E236-F239 PolarHBondContact O-N 2.88Å; F239-R241 VanDerWaalsContact C-N 3.29Å; F239-R241 PolarHBondContact O-N 3.11Å; F239-I242 PolarHBondContact O-N 3.41Å; F239-Q243 VanDerWaalsContact O-CB 3.26Å; F239-Q243 WeakPolarHBondContact O-CB 3.38Å; F239-Q243 PolarHBondContact O-N 2.77Å; F239-M255 HydrophobicContact CD2-CE 4Å; F239-M255 HydrophobicContact CD2-SD 3.92Å; F239-M255 HydrophobicContact CE2-CE 3.8Å; F239-M255 HydrophobicContact CE2-SD 3.78Å; F239-Y258 HydrophobicContact CB-CE1 3.99Å; F239-Y258 HydrophobicContact CB-CE2 4.24Å; F239-Y258 HydrophobicContact CD2-CD1 4.2Å; F239-Y258 AromaticContact CD2-CE1 3.63Å; F239-Y258 HydrophobicContact CD2-CE1 3.63Å; F239-Y258 HydrophobicContact CG-CE1 4.23Å
240	L	96.3	Very high	95.9	Very high	94 Å²	94	83 Å²	83	49%	0.492	40%	0.403	S	S	.	.	H	α-helix	trans	-61.7	-39.6	178.1	-68.1	172.9	0	0	0	111.3	E236 E237 Q243 A244	E236-L240 WeakPolarHBondContact O-CG 3.37Å; E236-L240 PolarHBondContact O-N 3.41Å; E237-L240 PolarHBondContact O-N 3.48Å; L240-Q243 PolarHBondContact O-N 3.44Å; L240-A244 WeakPolarHBondContact O-CB 3.29Å; L240-A244 PolarHBondContact O-N 3.36Å
241	R	95.3	Very high	95.7	Very high	139 Å²	139	81.9 Å²	81.9	53%	0.525	40%	0.396	S	S	.	.	H	α-helix	trans	-60.9	-45.1	176.5	-172.4	-178.3	73.9	103.5	0.3	112.2	E237 E238 F239	E237-R241 WeakPolarHBondContact O-CB 3.47Å; E237-R241 PolarHBondContact O-N 3.42Å; E238-R241 WeakPolarHBondContact O-CB 3.46Å; E238-R241 PolarHBondContact O-N 2.97Å; E238-R241 IonicContact OE1-CZ 3.24Å; E238-R241 IonicContact OE1-NE 3.91Å; E238-R241 PolarHBondContact OE1-NE 3.33Å; E238-R241 IonicContact OE1-NH2 3.67Å; E238-R241 IonicContact OE2-CZ 3.41Å; E238-R241 IonicContact OE2-NE 2.68Å; E238-R241 PolarHBondContact OE2-NE 3.21Å; E238-R241 IonicContact OE2-NH2 2.68Å; E238-R241 PolarHBondContact OE2-NH2 2.82Å; F239-R241 VanDerWaalsContact C-N 3.29Å; F239-R241 PolarHBondContact O-N 3.11Å
242	I	94.8	Very high	95.6	Very high	8 Å²	8	88.2 Å²	88.2	4%	0.041	43%	0.426	C	S	.	.	H	α-helix	trans	-71.1	-41.9	177.8	-61	165	0	0	0	110	E238 F239 A244 K245 K251 Q254 M255 Y258	E238-I242 WeakPolarHBondContact O-CG1 3.3Å; E238-I242 PolarHBondContact O-N 3.23Å; F239-I242 PolarHBondContact O-N 3.41Å; I242-A244 VanDerWaalsContact C-N 3.29Å; I242-A244 PolarHBondContact O-N 3.15Å; I242-K245 WeakPolarHBondContact O-CB 3.26Å; I242-K245 PolarHBondContact O-N 3.41Å; I242-K245 VanDerWaalsContact O-N 3.1Å; I242-K251 HydrophobicContact CG2-CG 4.27Å; I242-K251 WeakPolarHBondContact O-CE 3.49Å; I242-Q254 HydrophobicContact CD1-CB 4.37Å; I242-Q254 HydrophobicContact CG1-CB 4.46Å; I242-Q254 HydrophobicContact CG2-CB 3.98Å; I242-M255 HydrophobicContact CB-CE 4.21Å; I242-M255 HydrophobicContact CG2-CB 4.41Å; I242-M255 HydrophobicContact CG2-CE 3.77Å; I242-Y258 HydrophobicContact CD1-CD2 4.49Å; I242-Y258 HydrophobicContact CD1-CG 4.2Å
243	Q	94.4	Very high	95.5	Very high	100 Å²	100	90.2 Å²	90.2	47%	0.467	43%	0.433	S	S	.	.	H	α-helix	trans	-61.4	-37	-179.3	-171.7	177	30.9	0	0	112.5	F239 L240 K245 K251	F239-Q243 VanDerWaalsContact O-CB 3.26Å; F239-Q243 WeakPolarHBondContact O-CB 3.38Å; F239-Q243 PolarHBondContact O-N 2.77Å; L240-Q243 PolarHBondContact O-N 3.44Å; Q243-K245 PolarHBondContact O-N 3.01Å; Q243-K251 PolarHBondContact O-NZ 3.16Å
244	A	95.6	Very high	95.4	Very high	90 Å²	90	86.9 Å²	86.9	74%	0.744	42%	0.419	S	S	*	.	T	Hydrogen-bonded Turn	trans	-68.9	-13.9	177.9	0	0	0	0	0	114.2	L240 I242	L240-A244 WeakPolarHBondContact O-CB 3.29Å; L240-A244 PolarHBondContact O-N 3.36Å; I242-A244 VanDerWaalsContact C-N 3.29Å; I242-A244 PolarHBondContact O-N 3.15Å
245	K	94.8	Very high	95.3	Very high	67 Å²	67	88 Å²	88	29%	0.291	43%	0.425	S	S	.	.	S	Bend	trans	-68.2	150.4	174.4	-65.1	-173.6	169.8	-167	0	110.9	I242 Q243 E250 K251 Q254	I242-K245 WeakPolarHBondContact O-CB 3.26Å; I242-K245 PolarHBondContact O-N 3.41Å; I242-K245 VanDerWaalsContact O-N 3.1Å; Q243-K245 PolarHBondContact O-N 3.01Å; K245-E250 IonicContact NZ-OE1 3.25Å; K245-E250 PolarHBondContact NZ-OE1 2.64Å; K245-K251 HydrophobicContact CB-CD 4.33Å; K245-K251 HydrophobicContact CB-CG 4.4Å; K245-K251 WeakPolarHBondContact O-CD 3.35Å; K245-K251 WeakPolarHBondContact O-CE 3.32Å; K245-K251 PolarHBondContact O-NZ 2.99Å; K245-Q254 VanDerWaalsContact NZ-CD 3.3Å; K245-Q254 VanDerWaalsContact NZ-NE2 3.11Å
246	K	94.9	Very high	95.3	Very high	188 Å²	188	90.6 Å²	90.6	82%	0.817	45%	0.446	S	S	*	.	P	Polyproline II helix	trans	-61.3	148.2	172.4	-66	-177	179.3	-179.7	0	110	S248	K246-S248 PolarHBondContact O-N 3.05Å
247	E	95.1	Very high	95.2	Very high	149 Å²	149	89.9 Å²	89.9	70%	0.696	44%	0.443	S	S	*	.	S	Bend	trans	-59.6	122.7	175.6	-64.8	-55.8	147.9	0	0	110.6	K251	E247-K251 IonicContact OE1-NZ 2.79Å; E247-K251 PolarHBondContact OE1-NZ 3.33Å; E247-K251 IonicContact OE2-NZ 3.41Å
248	S	95.7	Very high	95.2	Very high	52 Å²	52	86.2 Å²	86.2	36%	0.364	43%	0.425	S	S	.	.	S	Bend	trans	-161.2	160.4	-179.9	65.8	0	0	0	0	109.6	K246 E250 K251 E252	K246-S248 PolarHBondContact O-N 3.05Å; S248-E250 PolarHBondContact O-N 2.83Å; S248-K251 WeakPolarHBondContact O-CB 3.4Å; S248-K251 PolarHBondContact O-N 3.22Å; S248-K251 PolarHBondContact OG-N 3.01Å; S248-E252 PolarHBondContact O-N 3.49Å
249	E	95.6	Very high	95.2	Very high	150 Å²	150	91.8 Å²	91.8	70%	0.701	44%	0.444	S	S	*	.	H	α-helix	trans	-55.1	-40.1	171.9	-170.8	173.4	-167.9	0	0	111.4	K251 E252 E253	E249-K251 VanDerWaalsContact C-N 3.29Å; E249-K251 PolarHBondContact O-N 3.43Å; E249-E252 WeakPolarHBondContact O-CB 3.46Å; E249-E252 PolarHBondContact O-N 3.25Å; E249-E252 VanDerWaalsContact O-N 3.11Å; E249-E253 WeakPolarHBondContact O-CG 3.24Å; E249-E253 PolarHBondContact O-N 3.04Å
250	E	94.3	Very high	95.2	Very high	105 Å²	105	94.7 Å²	94.7	49%	0.491	46%	0.456	S	S	.	.	H	α-helix	trans	-58.3	-37.8	174.8	-168.5	-156.5	140.2	0	0	112.7	K245 S248 Q254	K245-E250 IonicContact NZ-OE1 3.25Å; K245-E250 PolarHBondContact NZ-OE1 2.64Å; S248-E250 PolarHBondContact O-N 2.83Å; E250-Q254 WeakPolarHBondContact O-CB 3.17Å; E250-Q254 VanDerWaalsContact O-CG 3.25Å; E250-Q254 WeakPolarHBondContact O-CG 3.44Å; E250-Q254 PolarHBondContact O-N 3.21Å; E250-Q254 PolarHBondContact OE1-NE2 3.41Å
251	K	94.7	Very high	95.1	Very high	20 Å²	20	94 Å²	94	9%	0.087	45%	0.45	C	S	.	.	H	α-helix	trans	-68.3	-41.1	177	-177.9	-175	179.6	175	0	111	I242 Q243 K245 E247 S248 E249 Q254 M255	I242-K251 HydrophobicContact CG2-CG 4.27Å; I242-K251 WeakPolarHBondContact O-CE 3.49Å; Q243-K251 PolarHBondContact O-NZ 3.16Å; K245-K251 HydrophobicContact CB-CD 4.33Å; K245-K251 HydrophobicContact CB-CG 4.4Å; K245-K251 WeakPolarHBondContact O-CD 3.35Å; K245-K251 WeakPolarHBondContact O-CE 3.32Å; K245-K251 PolarHBondContact O-NZ 2.99Å; E247-K251 IonicContact OE1-NZ 2.79Å; E247-K251 PolarHBondContact OE1-NZ 3.33Å; E247-K251 IonicContact OE2-NZ 3.41Å; S248-K251 WeakPolarHBondContact O-CB 3.4Å; S248-K251 PolarHBondContact O-N 3.22Å; S248-K251 PolarHBondContact OG-N 3.01Å; E249-K251 VanDerWaalsContact C-N 3.29Å; E249-K251 PolarHBondContact O-N 3.43Å; K251-Q254 PolarHBondContact O-N 2.79Å; K251-M255 VanDerWaalsContact O-CB 3.31Å; K251-M255 WeakPolarHBondContact O-CB 3.36Å; K251-M255 PolarHBondContact O-N 2.98Å
252	E	94.8	Very high	95.1	Very high	134 Å²	134	91.5 Å²	91.5	63%	0.626	44%	0.443	S	S	*	.	H	α-helix	trans	-63.1	-44.8	177.4	-66.6	-175.7	176	0	0	111.4	S248 E249 M255 A256	S248-E252 PolarHBondContact O-N 3.49Å; E249-E252 WeakPolarHBondContact O-CB 3.46Å; E249-E252 PolarHBondContact O-N 3.25Å; E249-E252 VanDerWaalsContact O-N 3.11Å; E252-M255 PolarHBondContact O-N 3.43Å; E252-A256 PolarHBondContact O-N 3.34Å
253	E	95.6	Very high	95.2	Very high	125 Å²	125	97.4 Å²	97.4	58%	0.584	47%	0.471	S	S	*	.	H	α-helix	trans	-59.5	-48.3	174.9	-71.3	-177.6	166.2	0	0	111.9	E249 M255 A256 E257	E249-E253 WeakPolarHBondContact O-CG 3.24Å; E249-E253 PolarHBondContact O-N 3.04Å; E253-M255 VanDerWaalsContact C-N 3.31Å; E253-M255 PolarHBondContact O-N 3.12Å; E253-A256 PolarHBondContact O-N 3.12Å; E253-E257 PolarHBondContact O-N 2.98Å
254	Q	94.8	Very high	95.2	Very high	52 Å²	52	95.1 Å²	95.1	24%	0.243	46%	0.464	C	S	.	.	H	α-helix	trans	-63.1	-37.6	178	-75.2	171.1	10.3	0	0	112.4	I242 K245 E250 K251 Y258	I242-Q254 HydrophobicContact CD1-CB 4.37Å; I242-Q254 HydrophobicContact CG1-CB 4.46Å; I242-Q254 HydrophobicContact CG2-CB 3.98Å; K245-Q254 VanDerWaalsContact NZ-CD 3.3Å; K245-Q254 VanDerWaalsContact NZ-NE2 3.11Å; E250-Q254 WeakPolarHBondContact O-CB 3.17Å; E250-Q254 VanDerWaalsContact O-CG 3.25Å; E250-Q254 WeakPolarHBondContact O-CG 3.44Å; E250-Q254 PolarHBondContact O-N 3.21Å; E250-Q254 PolarHBondContact OE1-NE2 3.41Å; K251-Q254 PolarHBondContact O-N 2.79Å; Q254-Y258 VanDerWaalsContact O-CB 3.26Å; Q254-Y258 WeakPolarHBondContact O-CB 3.26Å; Q254-Y258 PolarHBondContact O-N 2.53Å
255	M	95.3	Very high	95.1	Very high	27 Å²	27	91 Å²	91	13%	0.133	43%	0.429	C	S	.	.	H	α-helix	trans	-68.2	-36.4	176.7	-172.3	60.1	67.3	0	0	111.6	F239 I242 K251 E252 E253 Y258 R259	F239-M255 HydrophobicContact CD2-CE 4Å; F239-M255 HydrophobicContact CD2-SD 3.92Å; F239-M255 HydrophobicContact CE2-CE 3.8Å; F239-M255 HydrophobicContact CE2-SD 3.78Å; I242-M255 HydrophobicContact CB-CE 4.21Å; I242-M255 HydrophobicContact CG2-CB 4.41Å; I242-M255 HydrophobicContact CG2-CE 3.77Å; K251-M255 VanDerWaalsContact O-CB 3.31Å; K251-M255 WeakPolarHBondContact O-CB 3.36Å; K251-M255 PolarHBondContact O-N 2.98Å; E252-M255 PolarHBondContact O-N 3.43Å; E253-M255 VanDerWaalsContact C-N 3.31Å; E253-M255 PolarHBondContact O-N 3.12Å; M255-Y258 HydrophobicContact SD-CD1 4.04Å; M255-R259 VanDerWaalsContact O-CG 3.27Å; M255-R259 WeakPolarHBondContact O-CG 3.4Å; M255-R259 PolarHBondContact O-N 3.23Å; M255-R259 VanDerWaalsContact O-N 3.11Å
256	A	95.8	Very high	95.1	Very high	57 Å²	57	90.3 Å²	90.3	47%	0.471	43%	0.428	S	S	.	.	H	α-helix	trans	-66.6	-45.8	174.4	0	0	0	0	0	111.9	E252 E253 R259 K260	E252-A256 PolarHBondContact O-N 3.34Å; E253-A256 PolarHBondContact O-N 3.12Å; A256-R259 PolarHBondContact O-N 3.38Å; A256-K260 PolarHBondContact O-N 2.79Å
257	E	94.6	Very high	95.1	Very high	111 Å²	111	83.4 Å²	83.4	52%	0.519	40%	0.403	S	S	.	.	H	α-helix	trans	-63.2	-43.4	176.9	-174	61.1	-164.4	0	0	111.4	E253 R259 K260 Q261	E253-E257 PolarHBondContact O-N 2.98Å; E257-R259 VanDerWaalsContact C-N 3.33Å; E257-R259 PolarHBondContact O-N 3.29Å; E257-K260 PolarHBondContact O-N 2.83Å; E257-Q261 WeakPolarHBondContact O-CB 3.4Å; E257-Q261 PolarHBondContact O-N 2.88Å
258	Y	95.8	Very high	95.2	Very high	20 Å²	20	76.4 Å²	76.4	8%	0.078	37%	0.37	C	S	.	.	H	α-helix	trans	-55.7	-45.7	174	165.6	-101.1	0	0	0	112.2	L235 E238 F239 I242 Q254 M255 K260 Q261 K262	L235-Y258 HydrophobicContact CB-CE2 4.15Å; L235-Y258 HydrophobicContact CD2-CD2 4.37Å; L235-Y258 HydrophobicContact CD2-CE2 3.76Å; L235-Y258 VanDerWaalsContact O-CE2 3.24Å; L235-Y258 WeakPolarHBondContact O-CE2 3.25Å; L235-Y258 PolarHBondContact O-OH 3.1Å; L235-Y258 VanDerWaalsContact O-OH 3.1Å; E238-Y258 HydrophobicContact CB-CD2 4.42Å; E238-Y258 HydrophobicContact CB-CE2 4.4Å; F239-Y258 HydrophobicContact CB-CE1 3.99Å; F239-Y258 HydrophobicContact CB-CE2 4.24Å; F239-Y258 HydrophobicContact CD2-CD1 4.2Å; F239-Y258 AromaticContact CD2-CE1 3.63Å; F239-Y258 HydrophobicContact CD2-CE1 3.63Å; F239-Y258 HydrophobicContact CG-CE1 4.23Å; I242-Y258 HydrophobicContact CD1-CD2 4.49Å; I242-Y258 HydrophobicContact CD1-CG 4.2Å; Q254-Y258 VanDerWaalsContact O-CB 3.26Å; Q254-Y258 WeakPolarHBondContact O-CB 3.26Å; Q254-Y258 PolarHBondContact O-N 2.53Å; M255-Y258 HydrophobicContact SD-CD1 4.04Å; Y258-K260 VanDerWaalsContact C-N 3.33Å; Y258-K260 PolarHBondContact O-N 3.1Å; Y258-Q261 PolarHBondContact O-N 3.18Å; Y258-K262 HydrophobicContact CE1-CD 4.26Å; Y258-K262 VanDerWaalsContact O-CB 3.25Å; Y258-K262 WeakPolarHBondContact O-CB 3.34Å; Y258-K262 PolarHBondContact O-N 3.01Å
259	R	95.9	Very high	95.2	Very high	167 Å²	167	75.2 Å²	75.2	63%	0.63	36%	0.359	S	S	*	.	H	α-helix	trans	-60.6	-43.8	179.2	-74.4	169.7	-174.3	176.9	3.6	111.5	M255 A256 E257 K262 E263	M255-R259 VanDerWaalsContact O-CG 3.27Å; M255-R259 WeakPolarHBondContact O-CG 3.4Å; M255-R259 PolarHBondContact O-N 3.23Å; M255-R259 VanDerWaalsContact O-N 3.11Å; A256-R259 PolarHBondContact O-N 3.38Å; E257-R259 VanDerWaalsContact C-N 3.33Å; E257-R259 PolarHBondContact O-N 3.29Å; R259-K262 PolarHBondContact O-N 3Å; R259-E263 PolarHBondContact O-N 2.96Å
260	K	95.3	Very high	95.3	Very high	133 Å²	133	71.6 Å²	71.6	58%	0.578	34%	0.344	S	S	*	.	H	α-helix	trans	-65.3	-45.9	177.8	-172.9	-179	178.6	-172.6	0	111.6	A256 E257 Y258 K262 E263 V264	A256-K260 PolarHBondContact O-N 2.79Å; E257-K260 PolarHBondContact O-N 2.83Å; Y258-K260 VanDerWaalsContact C-N 3.33Å; Y258-K260 PolarHBondContact O-N 3.1Å; K260-K262 VanDerWaalsContact C-N 3.35Å; K260-K262 PolarHBondContact O-N 3.03Å; K260-E263 PolarHBondContact O-N 3.41Å; K260-V264 WeakPolarHBondContact O-CG2 3.24Å; K260-V264 PolarHBondContact O-N 2.94Å
261	Q	94.8	Very high	95.4	Very high	79 Å²	79	71.5 Å²	71.5	37%	0.369	34%	0.344	S	S	.	.	H	α-helix	trans	-63.2	-41.8	177.8	-173.2	179.6	-4.3	0	0	111.6	E257 Y258 V264 L265	E257-Q261 WeakPolarHBondContact O-CB 3.4Å; E257-Q261 PolarHBondContact O-N 2.88Å; Y258-Q261 PolarHBondContact O-N 3.18Å; Q261-V264 PolarHBondContact O-N 3.35Å; Q261-L265 HydrophobicContact CG-CD1 3.96Å; Q261-L265 HydrophobicContact CG-CG 4.32Å; Q261-L265 WeakPolarHBondContact O-CB 3.21Å; Q261-L265 WeakPolarHBondContact O-CG 3.36Å; Q261-L265 PolarHBondContact O-N 2.94Å
262	K	95.8	Very high	95.5	Very high	87 Å²	87	78.4 Å²	78.4	38%	0.378	37%	0.374	S	S	.	.	H	α-helix	trans	-57.5	-49.5	174.5	172	171.4	-176.9	174.6	0	111.4	L235 Y258 R259 K260 V264 L265 L266	L235-K262 HydrophobicContact CD1-CB 4.38Å; L235-K262 HydrophobicContact CD1-CG 4.16Å; L235-K262 HydrophobicContact CD2-CB 4.18Å; Y258-K262 HydrophobicContact CE1-CD 4.26Å; Y258-K262 VanDerWaalsContact O-CB 3.25Å; Y258-K262 WeakPolarHBondContact O-CB 3.34Å; Y258-K262 PolarHBondContact O-N 3.01Å; R259-K262 PolarHBondContact O-N 3Å; K260-K262 VanDerWaalsContact C-N 3.35Å; K260-K262 PolarHBondContact O-N 3.03Å; K262-V264 PolarHBondContact O-N 3.14Å; K262-L265 PolarHBondContact O-N 3.34Å; K262-L266 HydrophobicContact CD-CD1 4.39Å; K262-L266 HydrophobicContact CG-CD1 3.72Å; K262-L266 HydrophobicContact CG-CG 4.3Å; K262-L266 WeakPolarHBondContact O-CB 3.38Å; K262-L266 VanDerWaalsContact O-CG 3.23Å; K262-L266 WeakPolarHBondContact O-CG 3.32Å; K262-L266 PolarHBondContact O-N 2.98Å
263	E	95.2	Very high	95.5	Very high	133 Å²	133	75.4 Å²	75.4	62%	0.621	36%	0.36	S	S	*	.	H	α-helix	trans	-58.2	-49.5	178.4	-173.9	-179.9	176.3	0	0	111.1	R259 K260 L265 L266 C267	R259-E263 PolarHBondContact O-N 2.96Å; K260-E263 PolarHBondContact O-N 3.41Å; E263-L265 PolarHBondContact O-N 3.23Å; E263-L266 PolarHBondContact O-N 2.93Å; E263-C267 WeakPolarHBondContact O-CB 3.05Å; E263-C267 PolarHBondContact O-N 2.71Å; E263-C267 PolarHBondContact O-SG 3.16Å
264	V	94.5	Very high	95.6	Very high	52 Å²	52	69.5 Å²	69.5	32%	0.315	33%	0.332	S	S	.	.	H	α-helix	trans	-60.9	-46.2	-179.8	171.6	0	0	0	0	112.2	K260 Q261 K262 T371 Y372	K260-V264 WeakPolarHBondContact O-CG2 3.24Å; K260-V264 PolarHBondContact O-N 2.94Å; Q261-V264 PolarHBondContact O-N 3.35Å; K262-V264 PolarHBondContact O-N 3.14Å; V264-T371 HydrophobicContact CG1-CG2 3.45Å; V264-T371 VanDerWaalsContact CG1-CG2 3.45Å; V264-Y372 HydrophobicContact CG1-CE1 4.18Å; V264-Y372 WeakPolarHBondContact O-CE1 3.23Å
265	L	95	Very high	95.7	Very high	2 Å²	2	72.4 Å²	72.4	1%	0.01	35%	0.346	C	S	.	.	H	α-helix	trans	-68	-39	-179.7	-73	177	0	0	0	112.2	I231 L235 Q261 K262 E263 L268 V374 W378	I231-L265 HydrophobicContact CG2-CB 4.29Å; L235-L265 HydrophobicContact CD2-CD1 4.25Å; Q261-L265 HydrophobicContact CG-CD1 3.96Å; Q261-L265 HydrophobicContact CG-CG 4.32Å; Q261-L265 WeakPolarHBondContact O-CB 3.21Å; Q261-L265 WeakPolarHBondContact O-CG 3.36Å; Q261-L265 PolarHBondContact O-N 2.94Å; K262-L265 PolarHBondContact O-N 3.34Å; E263-L265 PolarHBondContact O-N 3.23Å; L265-L268 WeakPolarHBondContact O-CB 3.44Å; L265-L268 PolarHBondContact O-N 2.95Å; L265-V374 HydrophobicContact CD1-CG1 4.21Å; L265-V374 HydrophobicContact CD2-CG1 3.97Å; L265-W378 HydrophobicContact CD1-CZ3 4.35Å
266	L	94.9	Very high	95.8	Very high	54 Å²	54	75.5 Å²	75.5	28%	0.283	36%	0.36	S	S	.	.	H	α-helix	trans	-72.8	-31.6	179.1	-65.8	-179.2	0	0	0	112.4	I231 L232 L235 K262 E263 L268 F269	I231-L266 HydrophobicContact CG2-CD2 4.39Å; L232-L266 HydrophobicContact CD2-CD2 3.64Å; L232-L266 HydrophobicContact CG-CD2 4.45Å; L235-L266 HydrophobicContact CD1-CD2 4.23Å; L235-L266 HydrophobicContact CD1-CG 4.32Å; K262-L266 HydrophobicContact CD-CD1 4.39Å; K262-L266 HydrophobicContact CG-CD1 3.72Å; K262-L266 HydrophobicContact CG-CG 4.3Å; K262-L266 WeakPolarHBondContact O-CB 3.38Å; K262-L266 VanDerWaalsContact O-CG 3.23Å; K262-L266 WeakPolarHBondContact O-CG 3.32Å; K262-L266 PolarHBondContact O-N 2.98Å; E263-L266 PolarHBondContact O-N 2.93Å; L266-L268 PolarHBondContact O-N 2.66Å; L266-L268 VanDerWaalsContact O-N 3.11Å; L266-F269 PolarHBondContact O-N 2.88Å
267	C	94.6	Very high	95.8	Very high	43 Å²	43	73.8 Å²	73.8	29%	0.291	34%	0.343	S	S	.	.	T	Hydrogen-bonded Turn	trans	-60.4	-17.2	170.8	-76.3	0	0	0	0	113.4	E263 F269	E263-C267 WeakPolarHBondContact O-CB 3.05Å; E263-C267 PolarHBondContact O-N 2.71Å; E263-C267 PolarHBondContact O-SG 3.16Å; C267-F269 PolarHBondContact O-N 3.31Å
268	L	95.9	Very high	95.9	Very high	1 Å²	1	71.1 Å²	71.1	1%	0.005	33%	0.332	C	S	.	.	T	Hydrogen-bonded Turn	trans	-63.2	-33.3	172.6	-176.9	62.4	0	0	0	112	W224 F227 L265 L266 Y287 L290 L294 Y372	W224-L268 HydrophobicContact CH2-CD1 3.87Å; W224-L268 HydrophobicContact CH2-CD2 3.78Å; W224-L268 HydrophobicContact CH2-CG 3.53Å; W224-L268 HydrophobicContact CZ2-CG 3.97Å; W224-L268 HydrophobicContact CZ3-CD2 4.33Å; F227-L268 HydrophobicContact CD1-CD2 4.47Å; F227-L268 HydrophobicContact CE1-CD2 3.78Å; L265-L268 WeakPolarHBondContact O-CB 3.44Å; L265-L268 PolarHBondContact O-N 2.95Å; L266-L268 PolarHBondContact O-N 2.66Å; L266-L268 VanDerWaalsContact O-N 3.11Å; L268-Y287 WeakPolarHBondContact O-CE2 3.44Å; L268-Y287 PolarHBondContact O-OH 2.92Å; L268-L290 HydrophobicContact CD1-CD2 4.38Å; L268-L294 HydrophobicContact CD2-CD2 4.08Å; L268-Y372 HydrophobicContact CB-CD1 3.9Å; L268-Y372 HydrophobicContact CB-CE1 4.01Å; L268-Y372 HydrophobicContact CD1-CD1 4Å; L268-Y372 HydrophobicContact CD1-CD2 3.84Å; L268-Y372 HydrophobicContact CD1-CE1 4.11Å; L268-Y372 HydrophobicContact CD1-CE2 3.97Å; L268-Y372 HydrophobicContact CD1-CG 3.86Å; L268-Y372 HydrophobicContact CD2-CD1 4.19Å; L268-Y372 HydrophobicContact CD2-CG 4.08Å; L268-Y372 HydrophobicContact CG-CD1 4.24Å; L268-Y372 HydrophobicContact CG-CG 4.37Å
269	F	96.9	Very high	95.8	Very high	27 Å²	27	74.8 Å²	74.8	12%	0.118	36%	0.36	C	S	.	.	S	Bend	trans	-89.5	-5.7	-174.8	-59.7	-74.3	0	0	0	113.5	W224 F227 E228 I231 L266 C267 E271 Y287	W224-F269 HydrophobicContact CD2-CD1 4.31Å; W224-F269 HydrophobicContact CD2-CE1 4.09Å; W224-F269 AromaticContact CE2-CD1 3.57Å; W224-F269 AromaticContact CE2-CE1 3.75Å; W224-F269 HydrophobicContact CE3-CE1 4.47Å; W224-F269 HydrophobicContact CH2-CE1 4.37Å; W224-F269 AromaticContact CZ2-CD1 3.73Å; W224-F269 HydrophobicContact CZ2-CD1 3.73Å; W224-F269 AromaticContact CZ2-CE1 3.91Å; W224-F269 HydrophobicContact CZ2-CE1 3.91Å; W224-F269 AromaticContact NE1-CD1 3.53Å; F227-F269 HydrophobicContact CD1-CE1 4.11Å; F227-F269 AromaticContact CD1-CZ 3.76Å; F227-F269 HydrophobicContact CD1-CZ 3.76Å; F227-F269 HydrophobicContact CE1-CZ 4.21Å; F227-F269 HydrophobicContact CG-CZ 4.46Å; E228-F269 HydrophobicContact CB-CD1 3.77Å; E228-F269 HydrophobicContact CB-CE1 3.48Å; E228-F269 VanDerWaalsContact CB-CE1 3.48Å; E228-F269 HydrophobicContact CB-CE2 4.28Å; E228-F269 HydrophobicContact CB-CG 4.31Å; E228-F269 HydrophobicContact CB-CZ 3.76Å; E228-F269 HydrophobicContact CG-CD1 3.85Å; E228-F269 HydrophobicContact CG-CD2 4.07Å; E228-F269 HydrophobicContact CG-CE1 4Å; E228-F269 HydrophobicContact CG-CE2 4.19Å; E228-F269 HydrophobicContact CG-CG 3.9Å; E228-F269 HydrophobicContact CG-CZ 4.16Å; I231-F269 HydrophobicContact CB-CE2 4.36Å; I231-F269 HydrophobicContact CD1-CE2 3.82Å; I231-F269 HydrophobicContact CD1-CZ 3.8Å; I231-F269 HydrophobicContact CG2-CE2 4.29Å; L266-F269 PolarHBondContact O-N 2.88Å; C267-F269 PolarHBondContact O-N 3.31Å; F269-E271 PolarHBondContact O-N 3.19Å; F269-Y287 VanDerWaalsContact C-OH 3.29Å; F269-Y287 VanDerWaalsContact CA-OH 3.28Å; F269-Y287 WeakPolarHBondContact CA-OH 3.35Å; F269-Y287 PolarHBondContact O-OH 3.46Å
270	D	96.5	Very high	95.7	Very high	75 Å²	75	72.3 Å²	72.3	40%	0.401	35%	0.354	S	S	.	.			trans	-84.9	96	175.2	-173.3	-14.2	0	0	0	111	K272 H273 H274	D270-K272 VanDerWaalsContact C-N 3.31Å; D270-K272 PolarHBondContact O-N 2.96Å; D270-K272 WeakPolarHBondContact OD1-CB 3.35Å; D270-K272 PolarHBondContact OD1-N 3.21Å; D270-H273 HydrophobicContact CB-CB 3.82Å; D270-H273 VanDerWaalsContact CG-CB 3.44Å; D270-H273 PolarHBondContact O-N 3.17Å; D270-H273 PolarHBondContact OD1-N 3.48Å; D270-H274 PolarHBondContact O-N 2.86Å
271	E	96.9	Very high	95.6	Very high	103 Å²	103	66.8 Å²	66.8	48%	0.481	33%	0.334	S	S	.	.	H	α-helix	trans	-62.6	-34.8	178.1	-174.1	167.2	-153.7	0	0	112.5	F269 H274 E275 Y287	F269-E271 PolarHBondContact O-N 3.19Å; E271-H274 WeakPolarHBondContact O-CB 3.19Å; E271-H274 PolarHBondContact O-N 3.18Å; E271-E275 WeakPolarHBondContact O-CG 3.5Å; E271-E275 PolarHBondContact O-N 2.66Å; E271-Y287 HydrophobicContact CB-CD1 4.03Å; E271-Y287 HydrophobicContact CB-CE1 3.83Å; E271-Y287 HydrophobicContact CB-CG 4.49Å; E271-Y287 HydrophobicContact CG-CD1 3.65Å; E271-Y287 HydrophobicContact CG-CE1 3.98Å; E271-Y287 HydrophobicContact CG-CG 4.02Å; E271-Y287 WeakPolarHBondContact OE1-CD1 3.36Å
272	K	96.8	Very high	95.6	Very high	165 Å²	165	67.9 Å²	67.9	72%	0.717	34%	0.34	S	S	*	.	H	α-helix	trans	-69	-39.2	178.3	-67.7	-177	178.6	178.1	0	111.4	D270 H274 E275 H276	D270-K272 VanDerWaalsContact C-N 3.31Å; D270-K272 PolarHBondContact O-N 2.96Å; D270-K272 WeakPolarHBondContact OD1-CB 3.35Å; D270-K272 PolarHBondContact OD1-N 3.21Å; K272-H274 VanDerWaalsContact C-N 3.29Å; K272-E275 PolarHBondContact O-N 2.93Å; K272-H276 PolarHBondContact O-N 3.01Å
273	H	95.8	Very high	95.7	Very high	70 Å²	70	64.6 Å²	64.6	32%	0.324	33%	0.325	S	S	.	.	H	α-helix	trans	-62.4	-41.1	172.7	-175.4	70.9	0	0	0	111	D270 H276 L277	D270-H273 HydrophobicContact CB-CB 3.82Å; D270-H273 VanDerWaalsContact CG-CB 3.44Å; D270-H273 PolarHBondContact O-N 3.17Å; D270-H273 PolarHBondContact OD1-N 3.48Å; H273-H276 PolarHBondContact O-N 3.32Å; H273-L277 WeakPolarHBondContact O-CG 3.37Å; H273-L277 PolarHBondContact O-N 3.32Å; H273-L277 VanDerWaalsContact O-N 3.09Å
274	H	97.4	Very high	95.8	Very high	2 Å²	2	59.5 Å²	59.5	1%	0.009	30%	0.3	C	S	.	.	H	α-helix	trans	-59.4	-48	174.1	178.1	88.9	0	0	0	112.6	D270 E271 K272 H276 L277 L278 R283 L285 Y287	D270-H274 PolarHBondContact O-N 2.86Å; E271-H274 WeakPolarHBondContact O-CB 3.19Å; E271-H274 PolarHBondContact O-N 3.18Å; K272-H274 VanDerWaalsContact C-N 3.29Å; H274-H276 VanDerWaalsContact C-N 3.31Å; H274-H276 PolarHBondContact O-N 2.93Å; H274-L277 PolarHBondContact O-N 2.9Å; H274-L278 WeakPolarHBondContact NE2-CD1 3.5Å; H274-L278 PolarHBondContact O-N 3.37Å; H274-R283 VanDerWaalsContact ND1-CD 3.26Å; H274-R283 WeakPolarHBondContact ND1-CD 3.35Å; H274-R283 PolarHBondContact ND1-NH1 2.81Å; H274-L285 PolarHBondContact CE1-O 3Å; H274-L285 VanDerWaalsContact CE1-O 3.23Å; H274-L285 PolarHBondContact NE2-O 3.08Å; H274-L285 VanDerWaalsContact NE2-O 3.08Å; H274-Y287 HydrophobicContact CB-CD2 3.93Å; H274-Y287 HydrophobicContact CB-CE2 4.42Å; H274-Y287 AromaticContact CD2-CD2 3.99Å; H274-Y287 AromaticContact CG-CD2 3.68Å; H274-Y287 AromaticContact ND1-CD2 3.96Å; H274-Y287 VanDerWaalsContact NE2-CA 3.33Å; H274-Y287 WeakPolarHBondContact NE2-CA 3.24Å; H274-Y287 PolarHBondContact NE2-N 2.97Å
275	E	96.7	Very high	96	Very high	112 Å²	112	57 Å²	57	52%	0.523	29%	0.285	S	S	.	.	H	α-helix	trans	-58.9	-40.1	176.6	-73	176.8	169.8	0	0	112.6	E271 K272 L278 S279	E271-E275 WeakPolarHBondContact O-CG 3.5Å; E271-E275 PolarHBondContact O-N 2.66Å; K272-E275 PolarHBondContact O-N 2.93Å; E275-L278 WeakPolarHBondContact O-CB 3.42Å; E275-L278 PolarHBondContact O-N 2.66Å; E275-S279 PolarHBondContact O-N 3.33Å
276	H	97	Very high	96.1	Very high	93 Å²	93	58 Å²	58	43%	0.431	29%	0.292	S	S	.	.	H	α-helix	trans	-62.7	-43.5	175.5	177.8	71.2	0	0	0	112	K272 H273 H274 L278 S279 K280	K272-H276 PolarHBondContact O-N 3.01Å; H273-H276 PolarHBondContact O-N 3.32Å; H274-H276 VanDerWaalsContact C-N 3.31Å; H274-H276 PolarHBondContact O-N 2.93Å; H276-L278 VanDerWaalsContact C-N 3.33Å; H276-L278 PolarHBondContact O-N 2.87Å; H276-S279 PolarHBondContact O-N 3.39Å; H276-S279 PolarHBondContact O-OG 2.93Å; H276-K280 VanDerWaalsContact CE1-CE 3.47Å; H276-K280 WeakPolarHBondContact CE1-CE 3.47Å; H276-K280 VanDerWaalsContact NE2-CE 3.31Å; H276-K280 WeakPolarHBondContact NE2-CE 3.45Å; H276-K280 PolarHBondContact NE2-NZ 3.15Å; H276-K280 PolarHBondContact O-N 2.88Å
277	L	96.3	Very high	96.3	Very high	21 Å²	21	56.4 Å²	56.4	11%	0.11	28%	0.282	C	S	.	.	H	α-helix	trans	-66.5	-34.6	175.9	-64.9	178.2	0	0	0	112.3	H273 H274 K280 G281 E282 R283	H273-L277 WeakPolarHBondContact O-CG 3.37Å; H273-L277 PolarHBondContact O-N 3.32Å; H273-L277 VanDerWaalsContact O-N 3.09Å; H274-L277 PolarHBondContact O-N 2.9Å; L277-K280 PolarHBondContact O-N 3.03Å; L277-G281 PolarHBondContact O-N 2.89Å; L277-E282 HydrophobicContact CB-CB 4.31Å; L277-E282 HydrophobicContact CD2-CB 4.19Å; L277-E282 WeakPolarHBondContact CD2-OE2 3.24Å; L277-E282 PolarHBondContact O-N 3.3Å; L277-R283 HydrophobicContact CB-CB 4.36Å; L277-R283 HydrophobicContact CB-CG 3.9Å; L277-R283 HydrophobicContact CD1-CG 4.31Å; L277-R283 PolarHBondContact O-N 3.16Å
278	L	95.6	Very high	96.5	Very high	55 Å²	55	59 Å²	59	29%	0.288	29%	0.286	S	S	.	.	H	α-helix	trans	-61.8	-47.8	170.7	-84	170.8	0	0	0	111.5	H274 E275 H276 K280 G281 R283	H274-L278 WeakPolarHBondContact NE2-CD1 3.5Å; H274-L278 PolarHBondContact O-N 3.37Å; E275-L278 WeakPolarHBondContact O-CB 3.42Å; E275-L278 PolarHBondContact O-N 2.66Å; H276-L278 VanDerWaalsContact C-N 3.33Å; H276-L278 PolarHBondContact O-N 2.87Å; L278-K280 PolarHBondContact O-N 2.95Å; L278-K280 VanDerWaalsContact O-N 3.17Å; L278-G281 PolarHBondContact O-N 2.8Å; L278-R283 HydrophobicContact CD2-CB 4.05Å; L278-R283 HydrophobicContact CG-CB 4.17Å
279	S	94.6	Very high	96.6	Very high	97 Å²	97	58.9 Å²	58.9	68%	0.678	29%	0.285	S	S	*	.	H	α-helix	trans	-62.2	-27.1	-178.8	75.8	0	0	0	0	113.6	E275 H276	E275-S279 PolarHBondContact O-N 3.33Å; H276-S279 PolarHBondContact O-N 3.39Å; H276-S279 PolarHBondContact O-OG 2.93Å
280	K	94.3	Very high	96.7	Very high	115 Å²	115	57.8 Å²	57.8	50%	0.5	28%	0.281	S	S	.	.	T	Hydrogen-bonded Turn	trans	-83.4	-12.9	175.9	-72	-176.1	175.8	179.9	0	113.4	H276 L277 L278 E282	H276-K280 VanDerWaalsContact CE1-CE 3.47Å; H276-K280 WeakPolarHBondContact CE1-CE 3.47Å; H276-K280 VanDerWaalsContact NE2-CE 3.31Å; H276-K280 WeakPolarHBondContact NE2-CE 3.45Å; H276-K280 PolarHBondContact NE2-NZ 3.15Å; H276-K280 PolarHBondContact O-N 2.88Å; L277-K280 PolarHBondContact O-N 3.03Å; L278-K280 PolarHBondContact O-N 2.95Å; L278-K280 VanDerWaalsContact O-N 3.17Å; K280-E282 VanDerWaalsContact C-N 3.33Å; K280-E282 HydrophobicContact CB-CG 4.1Å; K280-E282 VanDerWaalsContact CD-OE1 3.25Å; K280-E282 WeakPolarHBondContact CD-OE1 3.39Å; K280-E282 IonicContact NZ-OE1 3.83Å
281	G	92.8	Very high	96.8	Very high	16 Å²	16	55.1 Å²	55.1	17%	0.165	27%	0.266	C	S	.	.	T	Hydrogen-bonded Turn	trans	66.4	36.9	-168.3	0	0	0	0	0	112.1	L277 L278 R284	L277-G281 PolarHBondContact O-N 2.89Å; L278-G281 PolarHBondContact O-N 2.8Å; G281-R284 PolarHBondContact O-NH1 3.48Å; G281-R284 PolarHBondContact O-NH2 2.84Å; G281-R284 VanDerWaalsContact O-NH2 3.08Å
282	E	94.8	Very high	96.8	Very high	103 Å²	103	50.2 Å²	50.2	48%	0.481	24%	0.243	S	C	.	.	S	Bend	trans	-92.3	-30	166	-68	179.7	-145.2	0	0	111.1	L277 K280	L277-E282 HydrophobicContact CB-CB 4.31Å; L277-E282 HydrophobicContact CD2-CB 4.19Å; L277-E282 WeakPolarHBondContact CD2-OE2 3.24Å; L277-E282 PolarHBondContact O-N 3.3Å; K280-E282 VanDerWaalsContact C-N 3.33Å; K280-E282 HydrophobicContact CB-CG 4.1Å; K280-E282 VanDerWaalsContact CD-OE1 3.25Å; K280-E282 WeakPolarHBondContact CD-OE1 3.39Å; K280-E282 IonicContact NZ-OE1 3.83Å
283	R	96.9	Very high	96.9	Very high	18 Å²	18	42.3 Å²	42.3	7%	0.068	21%	0.209	C	C	.	.			trans	-110.6	167	163.6	-65.9	-169.1	-171.7	-171.1	16.1	111.2	H274 L277 L278 D365 Y372	H274-R283 VanDerWaalsContact ND1-CD 3.26Å; H274-R283 WeakPolarHBondContact ND1-CD 3.35Å; H274-R283 PolarHBondContact ND1-NH1 2.81Å; L277-R283 HydrophobicContact CB-CB 4.36Å; L277-R283 HydrophobicContact CB-CG 3.9Å; L277-R283 HydrophobicContact CD1-CG 4.31Å; L277-R283 PolarHBondContact O-N 3.16Å; L278-R283 HydrophobicContact CD2-CB 4.05Å; L278-R283 HydrophobicContact CG-CB 4.17Å; R283-D365 VanDerWaalsContact CA-OD1 3.28Å; R283-D365 WeakPolarHBondContact CA-OD1 3.49Å; R283-D365 VanDerWaalsContact CB-OD1 3.3Å; R283-D365 WeakPolarHBondContact CB-OD1 3.45Å; R283-D365 VanDerWaalsContact CG-OD1 3.3Å; R283-D365 WeakPolarHBondContact CG-OD1 3.35Å; R283-Y372 PolarHBondContact NH2-OH 3.2Å
284	R	97.6	Very high	97	Very high	25 Å²	25	39 Å²	39	9%	0.094	19%	0.193	C	C	.	.			trans	-129.1	-40.5	-177.9	-58.1	-69.7	178.2	-72.5	-6.9	112.7	L172 L203 G281 V362 V364 D365	L172-R284 VanDerWaalsContact CD1-CZ 3.4Å; L172-R284 VanDerWaalsContact CD1-NE 3.35Å; L172-R284 VanDerWaalsContact CD1-NH2 3.26Å; L203-R284 HydrophobicContact CD1-CB 4.26Å; L203-R284 HydrophobicContact CD2-CB 4Å; G281-R284 PolarHBondContact O-NH1 3.48Å; G281-R284 PolarHBondContact O-NH2 2.84Å; G281-R284 VanDerWaalsContact O-NH2 3.08Å; R284-V362 WeakPolarHBondContact CG-O 3.36Å; R284-V364 HydrophobicContact CG-CG1 3.86Å; R284-D365 VanDerWaalsContact CA-OD2 3.31Å; R284-D365 WeakPolarHBondContact CA-OD2 3.35Å; R284-D365 WeakPolarHBondContact CB-OD2 3.41Å; R284-D365 PolarHBondContact N-OD2 2.84Å
285	L	98.4	Very high	97.1	Very high	1 Å²	1	39 Å²	39	1%	0.005	19%	0.193	C	C	.	.	S	Bend	trans	-84.3	142.1	-179.2	-65.9	176.5	0	0	0	111.4	L203 E207 L210 H274 A289 D365 L366	L203-L285 HydrophobicContact CD1-CD2 3.69Å; L203-L285 HydrophobicContact CD1-CG 4.43Å; E207-L285 HydrophobicContact CB-CD2 3.92Å; E207-L285 HydrophobicContact CG-CD2 4.37Å; L210-L285 HydrophobicContact CD1-CD1 4.07Å; L210-L285 HydrophobicContact CD1-CD2 4.4Å; H274-L285 PolarHBondContact CE1-O 3Å; H274-L285 VanDerWaalsContact CE1-O 3.23Å; H274-L285 PolarHBondContact NE2-O 3.08Å; H274-L285 VanDerWaalsContact NE2-O 3.08Å; L285-A289 HydrophobicContact CB-CB 4.14Å; L285-A289 HydrophobicContact CD2-CB 4.38Å; L285-D365 HydrophobicContact CD1-CB 3.99Å; L285-D365 HydrophobicContact CG-CB 4.29Å; L285-D365 PolarHBondContact N-OD2 2.58Å; L285-L366 HydrophobicContact CD1-CD2 4.18Å
286	S	98.5	Very high	97.1	Very high	22 Å²	22	33.7 Å²	33.7	15%	0.154	17%	0.169	C	C	.	.			trans	-54	157.6	168.4	84.2	0	0	0	0	111.9	E207 E211 R288 A289 L290	E207-S286 WeakPolarHBondContact OE1-CB 3.4Å; E207-S286 PolarHBondContact OE1-N 2.93Å; E211-S286 WeakPolarHBondContact OE1-CB 3.46Å; E211-S286 PolarHBondContact OE1-OG 2.75Å; S286-R288 VanDerWaalsContact C-N 3.27Å; S286-R288 PolarHBondContact O-N 3Å; S286-A289 PolarHBondContact O-N 3.29Å; S286-A289 VanDerWaalsContact O-N 3.16Å; S286-A289 WeakPolarHBondContact OG-CB 3.29Å; S286-A289 PolarHBondContact OG-N 3.13Å; S286-A289 VanDerWaalsContact OG-N 3.08Å; S286-L290 PolarHBondContact O-N 3.28Å
287	Y	98.4	Very high	97.2	Very high	21 Å²	21	30.3 Å²	30.3	8%	0.082	15%	0.152	C	C	.	.	H	α-helix	trans	-58.6	-44.4	-178.6	-172.9	-126.9	0	0	0	111	W224 L268 F269 E271 H274 L290 Q291	W224-Y287 AromaticContact CE2-CZ 3.88Å; W224-Y287 AromaticContact CZ2-CE2 3.87Å; W224-Y287 HydrophobicContact CZ2-CE2 3.87Å; W224-Y287 AromaticContact CZ2-CZ 3.63Å; W224-Y287 VanDerWaalsContact CZ2-OH 3.27Å; W224-Y287 WeakPolarHBondContact CZ2-OH 3.27Å; W224-Y287 AromaticContact NE1-CZ 3.72Å; W224-Y287 PolarHBondContact NE1-OH 3.39Å; W224-Y287 VanDerWaalsContact NE1-OH 3.07Å; L268-Y287 WeakPolarHBondContact O-CE2 3.44Å; L268-Y287 PolarHBondContact O-OH 2.92Å; F269-Y287 VanDerWaalsContact C-OH 3.29Å; F269-Y287 VanDerWaalsContact CA-OH 3.28Å; F269-Y287 WeakPolarHBondContact CA-OH 3.35Å; F269-Y287 PolarHBondContact O-OH 3.46Å; E271-Y287 HydrophobicContact CB-CD1 4.03Å; E271-Y287 HydrophobicContact CB-CE1 3.83Å; E271-Y287 HydrophobicContact CB-CG 4.49Å; E271-Y287 HydrophobicContact CG-CD1 3.65Å; E271-Y287 HydrophobicContact CG-CE1 3.98Å; E271-Y287 HydrophobicContact CG-CG 4.02Å; E271-Y287 WeakPolarHBondContact OE1-CD1 3.36Å; H274-Y287 HydrophobicContact CB-CD2 3.93Å; H274-Y287 HydrophobicContact CB-CE2 4.42Å; H274-Y287 AromaticContact CD2-CD2 3.99Å; H274-Y287 AromaticContact CG-CD2 3.68Å; H274-Y287 AromaticContact ND1-CD2 3.96Å; H274-Y287 VanDerWaalsContact NE2-CA 3.33Å; H274-Y287 WeakPolarHBondContact NE2-CA 3.24Å; H274-Y287 PolarHBondContact NE2-N 2.97Å; Y287-L290 WeakPolarHBondContact O-CB 3.35Å; Y287-L290 PolarHBondContact O-N 3.47Å; Y287-Q291 WeakPolarHBondContact O-CG 3.12Å; Y287-Q291 PolarHBondContact O-N 3.25Å; Y287-Q291 VanDerWaalsContact O-N 3.09Å
288	R	98.4	Very high	97.2	Very high	96 Å²	96	30 Å²	30	36%	0.362	15%	0.15	S	C	.	.	H	α-helix	trans	-66.9	-38.5	178.2	-171.3	-178.9	179.4	90.3	5.7	112.6	E211 L216 S286 L290 Q291 G292	E211-R288 HydrophobicContact CB-CG 4.23Å; E211-R288 HydrophobicContact CG-CB 4.1Å; E211-R288 HydrophobicContact CG-CG 4.18Å; E211-R288 PolarHBondContact O-NE 3.22Å; L216-R288 HydrophobicContact CD1-CG 4.29Å; S286-R288 VanDerWaalsContact C-N 3.27Å; S286-R288 PolarHBondContact O-N 3Å; R288-L290 VanDerWaalsContact C-N 3.3Å; R288-L290 PolarHBondContact O-N 3.33Å; R288-Q291 WeakPolarHBondContact O-CB 3.35Å; R288-Q291 PolarHBondContact O-N 3.05Å; R288-G292 PolarHBondContact O-N 3.16Å
289	A	98.6	Very high	97.3	Very high	0 Å²	0	28.1 Å²	28.1	0%	0	14%	0.139	C	C	.	.	H	α-helix	trans	-63.6	-38.2	174.1	0	0	0	0	0	111.8	E207 L210 E211 L285 S286 Q291 G292 A293	E207-A289 HydrophobicContact CB-CB 4.4Å; E207-A289 HydrophobicContact CG-CB 3.78Å; L210-A289 HydrophobicContact CB-CB 3.84Å; L210-A289 HydrophobicContact CD1-CB 4.32Å; E211-A289 HydrophobicContact CG-CB 4.01Å; L285-A289 HydrophobicContact CB-CB 4.14Å; L285-A289 HydrophobicContact CD2-CB 4.38Å; S286-A289 PolarHBondContact O-N 3.29Å; S286-A289 VanDerWaalsContact O-N 3.16Å; S286-A289 WeakPolarHBondContact OG-CB 3.29Å; S286-A289 PolarHBondContact OG-N 3.13Å; S286-A289 VanDerWaalsContact OG-N 3.08Å; A289-Q291 VanDerWaalsContact C-N 3.34Å; A289-Q291 PolarHBondContact O-N 2.88Å; A289-G292 PolarHBondContact O-N 2.78Å; A289-A293 PolarHBondContact O-N 3.26Å
290	L	98.3	Very high	97.4	Very high	4 Å²	4	26.2 Å²	26.2	2%	0.021	12%	0.117	C	C	.	.	H	α-helix	trans	-62.3	-40.9	174.9	-164	74.5	0	0	0	111.9	L268 S286 Y287 R288 A293 L294 D365 L369	L268-L290 HydrophobicContact CD1-CD2 4.38Å; S286-L290 PolarHBondContact O-N 3.28Å; Y287-L290 WeakPolarHBondContact O-CB 3.35Å; Y287-L290 PolarHBondContact O-N 3.47Å; R288-L290 VanDerWaalsContact C-N 3.3Å; R288-L290 PolarHBondContact O-N 3.33Å; L290-A293 PolarHBondContact O-N 3.46Å; L290-L294 WeakPolarHBondContact O-CB 3.46Å; L290-L294 PolarHBondContact O-N 3.03Å; L290-D365 HydrophobicContact CD1-CB 3.91Å; L290-L369 HydrophobicContact CD1-CD2 3.5Å; L290-L369 HydrophobicContact CD1-CG 4.2Å; L290-L369 HydrophobicContact CG-CD2 3.81Å
291	Q	98.4	Very high	97.3	Very high	18 Å²	18	27.1 Å²	27.1	8%	0.084	12%	0.123	C	C	.	.	H	α-helix	trans	-60.4	-44.8	173.4	-60.3	171.9	-5.2	0	0	111.3	L216 W224 Y287 R288 A289 L294 M295	L216-Q291 HydrophobicContact CD1-CB 4.35Å; L216-Q291 HydrophobicContact CD2-CB 3.8Å; W224-Q291 HydrophobicContact CD2-CG 3.67Å; W224-Q291 HydrophobicContact CE3-CB 4.03Å; W224-Q291 HydrophobicContact CE3-CG 3.53Å; W224-Q291 HydrophobicContact CG-CG 4.31Å; W224-Q291 HydrophobicContact CH2-CG 3.93Å; W224-Q291 HydrophobicContact CZ2-CG 4.11Å; W224-Q291 HydrophobicContact CZ3-CB 4.17Å; W224-Q291 HydrophobicContact CZ3-CG 3.66Å; Y287-Q291 WeakPolarHBondContact O-CG 3.12Å; Y287-Q291 PolarHBondContact O-N 3.25Å; Y287-Q291 VanDerWaalsContact O-N 3.09Å; R288-Q291 WeakPolarHBondContact O-CB 3.35Å; R288-Q291 PolarHBondContact O-N 3.05Å; A289-Q291 VanDerWaalsContact C-N 3.34Å; A289-Q291 PolarHBondContact O-N 2.88Å; Q291-L294 PolarHBondContact O-N 2.95Å; Q291-M295 WeakPolarHBondContact O-CB 3.33Å; Q291-M295 PolarHBondContact O-N 3.48Å
292	G	98.3	Very high	97.3	Very high	0 Å²	0	27.7 Å²	27.7	0%	0	12%	0.122	C	C	.	.	H	α-helix	trans	-62	-42.4	177.1	0	0	0	0	0	113	R288 A289 L294 M295 I296	R288-G292 PolarHBondContact O-N 3.16Å; A289-G292 PolarHBondContact O-N 2.78Å; G292-L294 VanDerWaalsContact C-N 3.34Å; G292-L294 PolarHBondContact O-N 3.25Å; G292-M295 WeakPolarHBondContact O-CB 3.39Å; G292-M295 PolarHBondContact O-N 3.07Å; G292-I296 WeakPolarHBondContact O-CG1 3.27Å; G292-I296 PolarHBondContact O-N 3.31Å
293	A	98.6	Very high	97.2	Very high	0 Å²	0	25.1 Å²	25.1	0%	0	11%	0.114	C	C	.	.	H	α-helix	trans	-63.7	-40.7	176.1	0	0	0	0	0	111.7	L210 A289 L290 I296 Y297 L312 L366 L369	L210-A293 HydrophobicContact CD1-CB 4.13Å; L210-A293 HydrophobicContact CD2-CB 4.12Å; A289-A293 PolarHBondContact O-N 3.26Å; L290-A293 PolarHBondContact O-N 3.46Å; A293-I296 PolarHBondContact O-N 3.35Å; A293-Y297 WeakPolarHBondContact O-CD2 3.34Å; A293-Y297 PolarHBondContact O-N 3.37Å; A293-L312 HydrophobicContact CB-CD1 4.26Å; A293-L366 HydrophobicContact CB-CD2 3.88Å; A293-L369 HydrophobicContact CB-CD1 3.63Å
294	L	98.1	Very high	97	Very high	1 Å²	1	25.2 Å²	25.2	1%	0.005	11%	0.114	C	C	.	.	H	α-helix	trans	-68.6	-37.4	177.3	-165.1	67.2	0	0	0	112.3	F223 W224 F227 L268 L290 Q291 G292 Y297 F298 L369	F223-L294 HydrophobicContact CE1-CB 4.39Å; F223-L294 HydrophobicContact CE1-CD2 4.49Å; F223-L294 HydrophobicContact CZ-CD2 4.28Å; F223-L294 HydrophobicContact CZ-CG 4.29Å; W224-L294 HydrophobicContact CZ3-CD2 4.06Å; F227-L294 HydrophobicContact CD1-CD2 4.23Å; F227-L294 HydrophobicContact CE1-CD2 3.59Å; F227-L294 HydrophobicContact CZ-CD2 4.19Å; L268-L294 HydrophobicContact CD2-CD2 4.08Å; L290-L294 WeakPolarHBondContact O-CB 3.46Å; L290-L294 PolarHBondContact O-N 3.03Å; Q291-L294 PolarHBondContact O-N 2.95Å; G292-L294 VanDerWaalsContact C-N 3.34Å; G292-L294 PolarHBondContact O-N 3.25Å; L294-Y297 PolarHBondContact O-N 3.02Å; L294-F298 HydrophobicContact CD1-CD2 4.33Å; L294-F298 HydrophobicContact CD1-CE2 3.7Å; L294-F298 HydrophobicContact CD1-CZ 3.8Å; L294-F298 HydrophobicContact CD2-CD2 4.49Å; L294-F298 HydrophobicContact CD2-CE2 3.7Å; L294-F298 HydrophobicContact CD2-CZ 4.35Å; L294-F298 HydrophobicContact CG-CD2 3.88Å; L294-F298 HydrophobicContact CG-CE2 3.42Å; L294-F298 VanDerWaalsContact CG-CE2 3.42Å; L294-F298 HydrophobicContact CG-CZ 4.06Å; L294-F298 WeakPolarHBondContact O-CD2 3.5Å; L294-F298 PolarHBondContact O-N 3.12Å; L294-L369 HydrophobicContact CB-CD2 4.37Å; L294-L369 HydrophobicContact CD1-CD2 4.2Å
295	M	97.7	Very high	97	Very high	1 Å²	1	24.3 Å²	24.3	1%	0.005	11%	0.111	C	C	.	.	H	α-helix	trans	-56.5	-51.2	170.6	-178.4	74.5	-174.9	0	0	110.5	T213 L216 F221 F223 Q291 G292 Y297 F298 Y299 F305 M382	T213-M295 HydrophobicContact CG2-CB 4.14Å; T213-M295 HydrophobicContact CG2-CG 3.96Å; L216-M295 HydrophobicContact CD2-CB 4.31Å; F221-M295 HydrophobicContact CD1-CE 3.88Å; F221-M295 HydrophobicContact CD1-SD 4.38Å; F221-M295 HydrophobicContact CE1-CE 3.94Å; F221-M295 HydrophobicContact CE1-SD 4.25Å; F223-M295 HydrophobicContact CB-SD 3.67Å; F223-M295 HydrophobicContact CD1-CB 4.09Å; F223-M295 HydrophobicContact CD1-SD 4.01Å; F223-M295 HydrophobicContact CD2-SD 3.71Å; F223-M295 HydrophobicContact CE1-CB 4.19Å; F223-M295 HydrophobicContact CE2-SD 4.38Å; F223-M295 HydrophobicContact CG-SD 3.5Å; F223-M295 WeakPolarHBondContact CG-SD 3.4Å; Q291-M295 WeakPolarHBondContact O-CB 3.33Å; Q291-M295 PolarHBondContact O-N 3.48Å; G292-M295 WeakPolarHBondContact O-CB 3.39Å; G292-M295 PolarHBondContact O-N 3.07Å; M295-Y297 VanDerWaalsContact C-N 3.29Å; M295-Y297 PolarHBondContact O-N 3.03Å; M295-F298 PolarHBondContact O-N 3.47Å; M295-Y299 HydrophobicContact CE-CD2 3.54Å; M295-Y299 HydrophobicContact CE-CE2 3.75Å; M295-Y299 HydrophobicContact CE-CG 4.34Å; M295-Y299 HydrophobicContact CG-CD2 4.14Å; M295-Y299 VanDerWaalsContact O-CD2 3.22Å; M295-Y299 WeakPolarHBondContact O-CD2 3.31Å; M295-Y299 PolarHBondContact O-N 2.78Å; M295-Y299 HydrophobicContact SD-CD2 3.39Å; M295-Y299 WeakPolarHBondContact SD-CD2 3.45Å; M295-Y299 HydrophobicContact SD-CE2 3.33Å; M295-Y299 WeakPolarHBondContact SD-CE2 3.41Å; M295-F305 HydrophobicContact CE-CE2 3.93Å; M295-F305 HydrophobicContact CE-CZ 4.22Å; M295-F305 HydrophobicContact CG-CE2 4.28Å; M295-F305 HydrophobicContact CG-CZ 4.14Å; M295-M382 HydrophobicContact CE-CE 3.43Å; M295-M382 VanDerWaalsContact CE-CE 3.43Å
296	I	98.2	Very high	96.9	Very high	1 Å²	1	28.7 Å²	28.7	1%	0.005	13%	0.131	C	C	.	.	H	α-helix	trans	-59.4	-40.8	177.1	-67.8	163.5	0	0	0	110.9	W209 L210 T213 G292 A293 R300 F305 P308 F309 L312	W209-I296 HydrophobicContact CH2-CD1 3.78Å; W209-I296 HydrophobicContact CZ3-CD1 4.13Å; L210-I296 HydrophobicContact CD2-CD1 3.67Å; T213-I296 HydrophobicContact CG2-CD1 4.32Å; T213-I296 HydrophobicContact CG2-CG1 4.01Å; G292-I296 WeakPolarHBondContact O-CG1 3.27Å; G292-I296 PolarHBondContact O-N 3.31Å; A293-I296 PolarHBondContact O-N 3.35Å; I296-R300 WeakPolarHBondContact O-CA 3.42Å; I296-R300 VanDerWaalsContact O-CB 3.24Å; I296-R300 WeakPolarHBondContact O-CB 3.36Å; I296-R300 PolarHBondContact O-N 3.06Å; I296-F305 HydrophobicContact CG1-CD1 3.94Å; I296-F305 HydrophobicContact CG1-CE1 4.21Å; I296-P308 HydrophobicContact CD1-CB 4.06Å; I296-P308 HydrophobicContact CG1-CB 4.31Å; I296-P308 HydrophobicContact CG2-CB 4.02Å; I296-F309 HydrophobicContact CG2-CB 3.86Å; I296-F309 HydrophobicContact CG2-CD2 4.41Å; I296-L312 HydrophobicContact CB-CD1 4.02Å; I296-L312 HydrophobicContact CD1-CD1 4.13Å; I296-L312 HydrophobicContact CG2-CD1 3.78Å
297	Y	97.8	Very high	96.8	Very high	22 Å²	22	29.4 Å²	29.4	9%	0.086	14%	0.135	C	C	.	.	H	α-helix	trans	-62.9	-46.7	179.6	-94	-142.1	0	0	0	113.4	A293 L294 M295 R300 F309 L312 M316 L366 L369	A293-Y297 WeakPolarHBondContact O-CD2 3.34Å; A293-Y297 PolarHBondContact O-N 3.37Å; L294-Y297 PolarHBondContact O-N 3.02Å; M295-Y297 VanDerWaalsContact C-N 3.29Å; M295-Y297 PolarHBondContact O-N 3.03Å; Y297-R300 PolarHBondContact O-NH1 3.1Å; Y297-F309 AromaticContact CD2-CD2 3.89Å; Y297-F309 HydrophobicContact CD2-CD2 3.89Å; Y297-F309 AromaticContact CD2-CE2 3.81Å; Y297-F309 HydrophobicContact CD2-CE2 3.81Å; Y297-F309 HydrophobicContact CE2-CD2 4.18Å; Y297-F309 AromaticContact CE2-CE2 3.93Å; Y297-F309 HydrophobicContact CE2-CE2 3.93Å; Y297-F309 HydrophobicContact CG-CE2 4.24Å; Y297-L312 HydrophobicContact CD2-CD1 4.07Å; Y297-L312 HydrophobicContact CE2-CB 4.22Å; Y297-L312 HydrophobicContact CE2-CD1 3.9Å; Y297-M316 WeakPolarHBondContact OH-CE 3.42Å; Y297-M316 PolarHBondContact OH-SD 3.31Å; Y297-L366 PolarHBondContact OH-O 3.47Å; Y297-L369 HydrophobicContact CE1-CB 4.25Å; Y297-L369 HydrophobicContact CE1-CD1 4.43Å
298	F	97.4	Very high	96.8	Very high	15 Å²	15	29 Å²	29	7%	0.066	13%	0.134	C	C	.	.	H	α-helix	trans	-73	-36.1	-177.1	-71.7	-39.8	0	0	0	112.8	F223 F227 L294 M295 L373 V374 I379	F223-F298 AromaticContact CE2-CD2 3.98Å; F223-F298 HydrophobicContact CE2-CD2 3.98Å; F223-F298 AromaticContact CZ-CD2 3.76Å; F223-F298 HydrophobicContact CZ-CD2 3.76Å; F223-F298 HydrophobicContact CZ-CE2 4.12Å; F227-F298 HydrophobicContact CD2-CE2 4.29Å; F227-F298 AromaticContact CE1-CE2 3.99Å; F227-F298 HydrophobicContact CE1-CE2 3.99Å; F227-F298 HydrophobicContact CE2-CD2 4.38Å; F227-F298 AromaticContact CE2-CE2 3.52Å; F227-F298 HydrophobicContact CE2-CE2 3.52Å; F227-F298 AromaticContact CE2-CZ 3.91Å; F227-F298 HydrophobicContact CE2-CZ 3.91Å; F227-F298 AromaticContact CZ-CE2 3.34Å; F227-F298 HydrophobicContact CZ-CE2 3.34Å; F227-F298 AromaticContact CZ-CZ 3.62Å; F227-F298 HydrophobicContact CZ-CZ 3.62Å; L294-F298 HydrophobicContact CD1-CD2 4.33Å; L294-F298 HydrophobicContact CD1-CE2 3.7Å; L294-F298 HydrophobicContact CD1-CZ 3.8Å; L294-F298 HydrophobicContact CD2-CD2 4.49Å; L294-F298 HydrophobicContact CD2-CE2 3.7Å; L294-F298 HydrophobicContact CD2-CZ 4.35Å; L294-F298 HydrophobicContact CG-CD2 3.88Å; L294-F298 HydrophobicContact CG-CE2 3.42Å; L294-F298 VanDerWaalsContact CG-CE2 3.42Å; L294-F298 HydrophobicContact CG-CZ 4.06Å; L294-F298 WeakPolarHBondContact O-CD2 3.5Å; L294-F298 PolarHBondContact O-N 3.12Å; M295-F298 PolarHBondContact O-N 3.47Å; F298-L373 HydrophobicContact CE1-CD2 3.8Å; F298-L373 HydrophobicContact CZ-CD2 4.44Å; F298-V374 HydrophobicContact CE1-CG2 4.49Å; F298-V374 HydrophobicContact CZ-CG2 4.21Å; F298-I379 HydrophobicContact CB-CD1 4.11Å; F298-I379 HydrophobicContact CB-CG2 3.91Å; F298-I379 HydrophobicContact CD1-CD1 3.49Å; F298-I379 VanDerWaalsContact CD1-CD1 3.49Å; F298-I379 HydrophobicContact CD1-CG1 3.94Å; F298-I379 HydrophobicContact CE1-CD1 4.12Å; F298-I379 HydrophobicContact CE1-CG1 4.29Å; F298-I379 HydrophobicContact CG-CD1 3.94Å; F298-I379 HydrophobicContact CG-CG1 4.14Å; F298-I379 HydrophobicContact CG-CG2 4.25Å
299	Y	96.8	Very high	96.8	Very high	15 Å²	15	27 Å²	27	6%	0.059	13%	0.129	C	C	.	.	T	Hydrogen-bonded Turn	trans	-107.8	22.5	-176.9	-53.7	-74.9	0	0	0	113.6	F221 F223 M295 E301 E302 I379 P380 M382	F221-Y299 HydrophobicContact CE1-CE2 4.21Å; F223-Y299 AromaticContact CD2-CE2 3.85Å; F223-Y299 HydrophobicContact CD2-CE2 3.85Å; F223-Y299 AromaticContact CE2-CE2 3.92Å; F223-Y299 HydrophobicContact CE2-CE2 3.92Å; M295-Y299 HydrophobicContact CE-CD2 3.54Å; M295-Y299 HydrophobicContact CE-CE2 3.75Å; M295-Y299 HydrophobicContact CE-CG 4.34Å; M295-Y299 HydrophobicContact CG-CD2 4.14Å; M295-Y299 VanDerWaalsContact O-CD2 3.22Å; M295-Y299 WeakPolarHBondContact O-CD2 3.31Å; M295-Y299 PolarHBondContact O-N 2.78Å; M295-Y299 HydrophobicContact SD-CD2 3.39Å; M295-Y299 WeakPolarHBondContact SD-CD2 3.45Å; M295-Y299 HydrophobicContact SD-CE2 3.33Å; M295-Y299 WeakPolarHBondContact SD-CE2 3.41Å; Y299-E301 PolarHBondContact O-N 3.19Å; Y299-E302 WeakPolarHBondContact O-CB 3.22Å; Y299-E302 WeakPolarHBondContact O-CG 3.43Å; Y299-E302 PolarHBondContact O-N 2.95Å; Y299-I379 HydrophobicContact CE1-CG2 3.79Å; Y299-I379 HydrophobicContact CE2-CG2 4.43Å; Y299-P380 WeakPolarHBondContact CE1-O 3.44Å; Y299-P380 WeakPolarHBondContact OH-CB 3.45Å; Y299-P380 PolarHBondContact OH-O 3.03Å; Y299-M382 HydrophobicContact CD1-CE 3.27Å; Y299-M382 HydrophobicContact CD1-CG 3.95Å; Y299-M382 HydrophobicContact CD1-SD 4.46Å; Y299-M382 HydrophobicContact CD2-CE 3.65Å; Y299-M382 HydrophobicContact CE1-CE 3.47Å; Y299-M382 VanDerWaalsContact CE1-CE 3.47Å; Y299-M382 HydrophobicContact CE1-CG 3.79Å; Y299-M382 HydrophobicContact CE1-SD 4.32Å; Y299-M382 HydrophobicContact CE2-CE 3.86Å; Y299-M382 HydrophobicContact CG-CE 3.36Å
300	R	96.5	Very high	96.8	Very high	56 Å²	56	31.2 Å²	31.2	21%	0.211	15%	0.148	C	C	.	.	T	Hydrogen-bonded Turn	trans	-54.3	-18.9	-177.7	67	-172.6	-176.5	-67.4	-23.1	116.1	I296 Y297 Q306 F309 R376	I296-R300 WeakPolarHBondContact O-CA 3.42Å; I296-R300 VanDerWaalsContact O-CB 3.24Å; I296-R300 WeakPolarHBondContact O-CB 3.36Å; I296-R300 PolarHBondContact O-N 3.06Å; Y297-R300 PolarHBondContact O-NH1 3.1Å; R300-Q306 WeakPolarHBondContact O-CA 3.47Å; R300-Q306 WeakPolarHBondContact O-CG 3.39Å; R300-F309 HydrophobicContact CB-CB 3.69Å; R300-F309 HydrophobicContact CB-CD1 4.03Å; R300-F309 HydrophobicContact CB-CD2 3.68Å; R300-F309 HydrophobicContact CB-CE2 4.35Å; R300-F309 HydrophobicContact CB-CG 3.5Å; R300-F309 HydrophobicContact CG-CD1 4.48Å; R300-F309 HydrophobicContact CG-CD2 4.42Å; R300-F309 HydrophobicContact CG-CG 4.34Å; R300-R376 VanDerWaalsContact NH1-NH1 3.18Å
301	E	93.9	Very high	96.8	Very high	134 Å²	134	31.1 Å²	31.1	63%	0.626	15%	0.147	S	C	*	.	T	Hydrogen-bonded Turn	trans	-84.9	-17.9	180	-70.7	166.7	-159.7	0	0	112.1	Y299 Q306	Y299-E301 PolarHBondContact O-N 3.19Å; E301-Q306 PolarHBondContact O-NE2 3Å
302	E	92.9	Very high	96.9	Very high	29 Å²	29	30.2 Å²	30.2	14%	0.136	14%	0.143	C	C	.	.	S	Bend	trans	-64.6	135.9	173.1	-59.2	-59.6	140.2	0	0	110.1	Y299 R304 F305 Q306 H387 L390	Y299-E302 WeakPolarHBondContact O-CB 3.22Å; Y299-E302 WeakPolarHBondContact O-CG 3.43Å; Y299-E302 PolarHBondContact O-N 2.95Å; E302-R304 VanDerWaalsContact C-N 3.32Å; E302-R304 PolarHBondContact O-N 3.37Å; E302-R304 VanDerWaalsContact O-N 3.14Å; E302-F305 HydrophobicContact CB-CD2 4.14Å; E302-F305 WeakPolarHBondContact O-CA 3.44Å; E302-F305 PolarHBondContact O-N 2.87Å; E302-Q306 PolarHBondContact O-N 3.1Å; E302-H387 IonicContact OE1-CE1 3.22Å; E302-H387 PolarHBondContact OE1-CE1 3.38Å; E302-H387 IonicContact OE1-ND1 3.15Å; E302-H387 PolarHBondContact OE1-ND1 2.9Å; E302-H387 IonicContact OE2-CE1 3.93Å; E302-H387 IonicContact OE2-ND1 3.77Å; E302-H387 PolarHBondContact OE2-ND1 2.95Å; E302-L390 HydrophobicContact CB-CB 4.25Å; E302-L390 HydrophobicContact CB-CD1 4.48Å; E302-L390 HydrophobicContact CG-CD1 4.21Å
303	P	92.6	Very high	96.9	Very high	49 Å²	49	32.2 Å²	32.2	32%	0.318	16%	0.156	S	C	.	.	H	α-helix	trans	-51.2	-44.1	-170.4	-30.6	36.2	0	0	0	114.8	F305 Q306 Y391	P303-F305 PolarHBondContact O-N 3.31Å; P303-Q306 PolarHBondContact O-N 3.21Å; P303-Y391 HydrophobicContact CG-CD1 3.85Å; P303-Y391 HydrophobicContact CG-CD2 3.95Å; P303-Y391 HydrophobicContact CG-CE1 3.77Å; P303-Y391 HydrophobicContact CG-CE2 3.9Å; P303-Y391 HydrophobicContact CG-CG 3.96Å
304	R	92.7	Very high	96.9	Very high	20 Å²	20	32.5 Å²	32.5	8%	0.075	16%	0.158	C	C	.	.	H	α-helix	trans	-65.2	-22.8	177.6	-76.3	180	77.9	-174.2	0	113.9	E106 E302 P308 F389 L390 T392 E394	E106-R304 IonicContact OE1-CZ 3.07Å; E106-R304 IonicContact OE1-NE 2.66Å; E106-R304 PolarHBondContact OE1-NE 2.71Å; E106-R304 IonicContact OE1-NH2 2.75Å; E106-R304 PolarHBondContact OE1-NH2 3.14Å; E106-R304 WeakPolarHBondContact OE2-CG 3.28Å; E106-R304 IonicContact OE2-NE 2.96Å; E106-R304 PolarHBondContact OE2-NE 2.94Å; E302-R304 VanDerWaalsContact C-N 3.32Å; E302-R304 PolarHBondContact O-N 3.37Å; E302-R304 VanDerWaalsContact O-N 3.14Å; R304-P308 WeakPolarHBondContact O-CD 3.3Å; R304-P308 WeakPolarHBondContact O-CG 3.49Å; R304-F389 VanDerWaalsContact CD-O 3.28Å; R304-F389 WeakPolarHBondContact CD-O 3.27Å; R304-F389 VanDerWaalsContact NH1-CZ 3.26Å; R304-F389 PolarHBondContact NH1-O 2.99Å; R304-L390 WeakPolarHBondContact CB-O 3.36Å; R304-L390 VanDerWaalsContact CG-O 3.23Å; R304-L390 WeakPolarHBondContact CG-O 3.26Å; R304-L390 PolarHBondContact N-O 2.84Å; R304-L390 VanDerWaalsContact N-O 3.14Å; R304-T392 WeakPolarHBondContact CD-O 3.45Å; R304-E394 IonicContact CZ-OE1 3.41Å; R304-E394 IonicContact NH1-OE1 3.22Å; R304-E394 IonicContact NH2-OE1 3.62Å; R304-E394 PolarHBondContact NH2-OE1 2.89Å
305	F	96.2	Very high	96.9	Very high	5 Å²	5	32.5 Å²	32.5	2%	0.022	16%	0.157	C	C	.	.	H	α-helix	trans	-101	-6.7	-177.3	-65.3	-39.4	0	0	0	115.2	T213 P214 M295 I296 E302 P303 F309 L390	T213-F305 HydrophobicContact CG2-CE1 3.8Å; T213-F305 HydrophobicContact CG2-CZ 4.02Å; P214-F305 HydrophobicContact CG-CE1 3.83Å; P214-F305 HydrophobicContact CG-CZ 3.85Å; M295-F305 HydrophobicContact CE-CE2 3.93Å; M295-F305 HydrophobicContact CE-CZ 4.22Å; M295-F305 HydrophobicContact CG-CE2 4.28Å; M295-F305 HydrophobicContact CG-CZ 4.14Å; I296-F305 HydrophobicContact CG1-CD1 3.94Å; I296-F305 HydrophobicContact CG1-CE1 4.21Å; E302-F305 HydrophobicContact CB-CD2 4.14Å; E302-F305 WeakPolarHBondContact O-CA 3.44Å; E302-F305 PolarHBondContact O-N 2.87Å; P303-F305 PolarHBondContact O-N 3.31Å; F305-F309 VanDerWaalsContact O-CB 3.31Å; F305-F309 WeakPolarHBondContact O-CB 3.4Å; F305-F309 PolarHBondContact O-N 3.12Å; F305-L390 HydrophobicContact CD2-CD1 4.41Å; F305-L390 HydrophobicContact CD2-CD2 4.33Å; F305-L390 HydrophobicContact CE1-CD2 4.35Å; F305-L390 HydrophobicContact CE2-CD1 3.77Å; F305-L390 HydrophobicContact CE2-CD2 3.58Å; F305-L390 HydrophobicContact CE2-CG 4.32Å; F305-L390 HydrophobicContact CZ-CD2 3.6Å
306	Q	96.3	Very high	97	Very high	94 Å²	94	33.9 Å²	33.9	44%	0.439	16%	0.164	S	C	.	.	H	α-helix	trans	-60.6	-53.1	179.7	-69	176.6	2.7	0	0	112.5	R300 E301 E302 P303 F309 Q310	R300-Q306 WeakPolarHBondContact O-CA 3.47Å; R300-Q306 WeakPolarHBondContact O-CG 3.39Å; E301-Q306 PolarHBondContact O-NE2 3Å; E302-Q306 PolarHBondContact O-N 3.1Å; P303-Q306 PolarHBondContact O-N 3.21Å; Q306-F309 PolarHBondContact O-N 3.09Å; Q306-Q310 WeakPolarHBondContact O-CG 3.48Å; Q306-Q310 PolarHBondContact O-N 3.24Å
307	V	97.6	Very high	97	Very high	37 Å²	37	36.7 Å²	36.7	22%	0.224	18%	0.179	C	C	.	.	H	α-helix	trans	-71.2	-41.6	178.8	-174.1	0	0	0	0	112	M109 M113 F309 Q310 L311	M109-V307 HydrophobicContact CB-CB 4.31Å; M109-V307 HydrophobicContact CB-CG1 3.82Å; M113-V307 HydrophobicContact CB-CG1 3.78Å; M113-V307 HydrophobicContact CG-CG1 4.21Å; V307-F309 VanDerWaalsContact C-N 3.29Å; V307-F309 PolarHBondContact O-N 3.13Å; V307-Q310 WeakPolarHBondContact O-CB 3.45Å; V307-Q310 PolarHBondContact O-N 3.01Å; V307-Q310 VanDerWaalsContact O-N 3.15Å; V307-L311 PolarHBondContact O-N 3.43Å
308	P	98.3	Very high	97	Very high	11 Å²	11	35.8 Å²	35.8	7%	0.071	18%	0.176	C	C	.	.	H	α-helix	trans	-49.6	-44.8	167.9	-36	41	0	0	0	114.4	M109 W209 I296 R304 L311 L312	M109-P308 HydrophobicContact CE-CG 4.19Å; W209-P308 HydrophobicContact CH2-CB 3.74Å; W209-P308 HydrophobicContact CH2-CG 4.38Å; W209-P308 HydrophobicContact CZ2-CB 3.91Å; W209-P308 HydrophobicContact CZ2-CG 4.05Å; I296-P308 HydrophobicContact CD1-CB 4.06Å; I296-P308 HydrophobicContact CG1-CB 4.31Å; I296-P308 HydrophobicContact CG2-CB 4.02Å; R304-P308 WeakPolarHBondContact O-CD 3.3Å; R304-P308 WeakPolarHBondContact O-CG 3.49Å; P308-L311 WeakPolarHBondContact O-CB 3.4Å; P308-L311 PolarHBondContact O-N 2.97Å; P308-L312 WeakPolarHBondContact O-CG 3.49Å; P308-L312 PolarHBondContact O-N 2.69Å
309	F	98.5	Very high	97.1	Very high	56 Å²	56	35.3 Å²	35.3	25%	0.246	17%	0.174	C	C	.	.	H	α-helix	trans	-65.7	-39.5	178.1	179.5	-101.8	0	0	0	112.4	I296 Y297 R300 F305 Q306 V307 L311 L312 T313	I296-F309 HydrophobicContact CG2-CB 3.86Å; I296-F309 HydrophobicContact CG2-CD2 4.41Å; Y297-F309 AromaticContact CD2-CD2 3.89Å; Y297-F309 HydrophobicContact CD2-CD2 3.89Å; Y297-F309 AromaticContact CD2-CE2 3.81Å; Y297-F309 HydrophobicContact CD2-CE2 3.81Å; Y297-F309 HydrophobicContact CE2-CD2 4.18Å; Y297-F309 AromaticContact CE2-CE2 3.93Å; Y297-F309 HydrophobicContact CE2-CE2 3.93Å; Y297-F309 HydrophobicContact CG-CE2 4.24Å; R300-F309 HydrophobicContact CB-CB 3.69Å; R300-F309 HydrophobicContact CB-CD1 4.03Å; R300-F309 HydrophobicContact CB-CD2 3.68Å; R300-F309 HydrophobicContact CB-CE2 4.35Å; R300-F309 HydrophobicContact CB-CG 3.5Å; R300-F309 HydrophobicContact CG-CD1 4.48Å; R300-F309 HydrophobicContact CG-CD2 4.42Å; R300-F309 HydrophobicContact CG-CG 4.34Å; F305-F309 VanDerWaalsContact O-CB 3.31Å; F305-F309 WeakPolarHBondContact O-CB 3.4Å; F305-F309 PolarHBondContact O-N 3.12Å; Q306-F309 PolarHBondContact O-N 3.09Å; V307-F309 VanDerWaalsContact C-N 3.29Å; V307-F309 PolarHBondContact O-N 3.13Å; F309-L311 VanDerWaalsContact C-N 3.3Å; F309-L311 PolarHBondContact O-N 3.39Å; F309-L312 PolarHBondContact O-N 3.3Å; F309-T313 PolarHBondContact O-N 3.29Å; F309-T313 PolarHBondContact O-OG1 2.96Å
310	Q	98.5	Very high	97.2	Very high	87 Å²	87	36.7 Å²	36.7	41%	0.407	18%	0.184	S	C	.	.	H	α-helix	trans	-63.3	-36.3	173.5	-68.3	172.7	8.4	0	0	112.2	M113 Q306 V307 T313 S314	M113-Q310 HydrophobicContact CG-CB 3.9Å; Q306-Q310 WeakPolarHBondContact O-CG 3.48Å; Q306-Q310 PolarHBondContact O-N 3.24Å; V307-Q310 WeakPolarHBondContact O-CB 3.45Å; V307-Q310 PolarHBondContact O-N 3.01Å; V307-Q310 VanDerWaalsContact O-N 3.15Å; Q310-T313 PolarHBondContact O-N 3.2Å; Q310-S314 WeakPolarHBondContact O-CB 3.49Å; Q310-S314 PolarHBondContact O-N 3.27Å; Q310-S314 PolarHBondContact O-OG 3.43Å
311	L	98.6	Very high	97.3	Very high	2 Å²	2	34.7 Å²	34.7	1%	0.01	18%	0.178	C	C	.	.	H	α-helix	trans	-62.9	-51.7	173.3	175.7	60.8	0	0	0	110.8	F98 M109 V112 M116 W209 V307 P308 F309 T313 S314 L315	F98-L311 HydrophobicContact CZ-CD2 4.11Å; M109-L311 HydrophobicContact CE-CD2 3.95Å; V112-L311 HydrophobicContact CG1-CD1 4.01Å; V112-L311 HydrophobicContact CG1-CD2 4.05Å; M116-L311 HydrophobicContact CB-CD1 4.14Å; M116-L311 HydrophobicContact CG-CD1 3.73Å; W209-L311 HydrophobicContact CH2-CD2 4.28Å; W209-L311 HydrophobicContact CZ3-CD2 4.36Å; V307-L311 PolarHBondContact O-N 3.43Å; P308-L311 WeakPolarHBondContact O-CB 3.4Å; P308-L311 PolarHBondContact O-N 2.97Å; F309-L311 VanDerWaalsContact C-N 3.3Å; F309-L311 PolarHBondContact O-N 3.39Å; L311-T313 PolarHBondContact O-N 2.6Å; L311-S314 WeakPolarHBondContact O-CB 3.33Å; L311-S314 PolarHBondContact O-N 3.02Å; L311-L315 HydrophobicContact CD1-CG 4.38Å; L311-L315 HydrophobicContact CG-CD1 4.47Å; L311-L315 WeakPolarHBondContact O-CG 3.27Å; L311-L315 PolarHBondContact O-N 3.21Å
312	L	98.7	Very high	97.5	Very high	0 Å²	0	28.7 Å²	28.7	0%	0	15%	0.15	C	C	.	.	H	α-helix	trans	-57.1	-39.8	177.4	-63.8	-173.4	0	0	0	112.2	W209 L210 A293 I296 Y297 P308 F309 L315 M316 L366	W209-L312 HydrophobicContact CZ3-CD2 4.25Å; L210-L312 HydrophobicContact CD2-CD2 4.28Å; A293-L312 HydrophobicContact CB-CD1 4.26Å; I296-L312 HydrophobicContact CB-CD1 4.02Å; I296-L312 HydrophobicContact CD1-CD1 4.13Å; I296-L312 HydrophobicContact CG2-CD1 3.78Å; Y297-L312 HydrophobicContact CD2-CD1 4.07Å; Y297-L312 HydrophobicContact CE2-CB 4.22Å; Y297-L312 HydrophobicContact CE2-CD1 3.9Å; P308-L312 WeakPolarHBondContact O-CG 3.49Å; P308-L312 PolarHBondContact O-N 2.69Å; F309-L312 PolarHBondContact O-N 3.3Å; L312-L315 HydrophobicContact CD2-CD1 4.23Å; L312-L315 PolarHBondContact O-N 3.24Å; L312-M316 PolarHBondContact O-N 2.93Å; L312-L366 HydrophobicContact CB-CD1 4.31Å; L312-L366 HydrophobicContact CD2-CD1 4.07Å; L312-L366 HydrophobicContact CD2-CD2 4.24Å
313	T	98.7	Very high	97.7	Very high	42 Å²	42	28.9 Å²	28.9	26%	0.258	15%	0.153	S	C	.	.	H	α-helix	trans	-62	-45.5	174.4	-55.7	0	0	0	0	111.4	F309 Q310 L311 L315 M316 D317	F309-T313 PolarHBondContact O-N 3.29Å; F309-T313 PolarHBondContact O-OG1 2.96Å; Q310-T313 PolarHBondContact O-N 3.2Å; L311-T313 PolarHBondContact O-N 2.6Å; T313-L315 VanDerWaalsContact C-N 3.31Å; T313-L315 PolarHBondContact O-N 3.49Å; T313-M316 PolarHBondContact O-N 3.2Å; T313-D317 PolarHBondContact O-N 2.96Å
314	S	98.8	Very high	98	Very high	6 Å²	6	31.7 Å²	31.7	4%	0.042	16%	0.16	C	C	.	.	H	α-helix	trans	-64.5	-34.2	178.4	-59.8	0	0	0	0	112.5	Q310 L311 D317 I318	Q310-S314 WeakPolarHBondContact O-CB 3.49Å; Q310-S314 PolarHBondContact O-N 3.27Å; Q310-S314 PolarHBondContact O-OG 3.43Å; L311-S314 WeakPolarHBondContact O-CB 3.33Å; L311-S314 PolarHBondContact O-N 3.02Å; S314-D317 PolarHBondContact O-N 3.06Å; S314-I318 VanDerWaalsContact O-CG1 3.3Å; S314-I318 WeakPolarHBondContact O-CG1 3.18Å; S314-I318 PolarHBondContact O-N 2.88Å
315	L	98.8	Very high	98.3	Very high	0 Å²	0	32.1 Å²	32.1	0%	0	16%	0.162	C	C	.	.	H	α-helix	trans	-64	-43.9	174.8	-64.3	175.6	0	0	0	111.6	M116 L202 V206 L311 L312 T313 I318 D319 F363 L366	M116-L315 HydrophobicContact CE-CD2 3.73Å; L202-L315 HydrophobicContact CD2-CD2 3.77Å; L202-L315 HydrophobicContact CG-CD2 4.49Å; V206-L315 HydrophobicContact CG1-CD1 3.89Å; V206-L315 HydrophobicContact CG2-CD1 3.99Å; L311-L315 HydrophobicContact CD1-CG 4.38Å; L311-L315 HydrophobicContact CG-CD1 4.47Å; L311-L315 WeakPolarHBondContact O-CG 3.27Å; L311-L315 PolarHBondContact O-N 3.21Å; L312-L315 HydrophobicContact CD2-CD1 4.23Å; L312-L315 PolarHBondContact O-N 3.24Å; T313-L315 VanDerWaalsContact C-N 3.31Å; T313-L315 PolarHBondContact O-N 3.49Å; L315-I318 PolarHBondContact O-N 3.23Å; L315-D319 PolarHBondContact O-N 3.04Å; L315-F363 HydrophobicContact CB-CD1 4.37Å; L315-F363 HydrophobicContact CB-CD2 3.9Å; L315-F363 HydrophobicContact CB-CE2 4.12Å; L315-F363 HydrophobicContact CB-CG 4.04Å; L315-F363 HydrophobicContact CB-CZ 4.45Å; L315-F363 HydrophobicContact CD1-CD1 4.15Å; L315-F363 HydrophobicContact CD1-CE1 3.88Å; L315-F363 HydrophobicContact CD1-CZ 4.15Å; L315-F363 HydrophobicContact CD2-CE1 4.38Å; L315-F363 HydrophobicContact CD2-CE2 3.86Å; L315-F363 HydrophobicContact CD2-CZ 3.79Å; L315-F363 HydrophobicContact CG-CE1 4.5Å; L315-F363 HydrophobicContact CG-CE2 4.41Å; L315-F363 HydrophobicContact CG-CZ 4.34Å; L315-L366 HydrophobicContact CB-CD1 4.15Å; L315-L366 HydrophobicContact CD1-CD1 4.38Å
316	M	98.8	Very high	98.4	Very high	30 Å²	30	32.4 Å²	32.4	15%	0.148	16%	0.163	C	C	.	.	H	α-helix	trans	-64.3	-39	172.8	-68.3	-171.2	-65.9	0	0	112.3	Y297 L312 T313 I318 D319 T320 L366 F367	Y297-M316 WeakPolarHBondContact OH-CE 3.42Å; Y297-M316 PolarHBondContact OH-SD 3.31Å; L312-M316 PolarHBondContact O-N 2.93Å; T313-M316 PolarHBondContact O-N 3.2Å; M316-I318 VanDerWaalsContact C-N 3.33Å; M316-I318 PolarHBondContact O-N 3.32Å; M316-D319 PolarHBondContact O-N 2.71Å; M316-T320 WeakPolarHBondContact O-CB 3.4Å; M316-T320 PolarHBondContact O-N 3.45Å; M316-T320 PolarHBondContact O-OG1 3.08Å; M316-L366 HydrophobicContact CG-CB 3.67Å; M316-L366 HydrophobicContact CG-CD1 4.15Å; M316-L366 HydrophobicContact SD-CB 3.82Å; M316-F367 HydrophobicContact CB-CE1 4.07Å; M316-F367 HydrophobicContact CB-CE2 3.87Å; M316-F367 HydrophobicContact CB-CZ 3.59Å; M316-F367 HydrophobicContact CG-CD2 4.04Å; M316-F367 HydrophobicContact CG-CE1 4.38Å; M316-F367 HydrophobicContact CG-CE2 3.75Å; M316-F367 HydrophobicContact CG-CG 4.49Å; M316-F367 HydrophobicContact CG-CZ 3.96Å; M316-F367 WeakPolarHBondContact O-CZ 3.37Å; M316-F367 HydrophobicContact SD-CD1 4.29Å; M316-F367 HydrophobicContact SD-CD2 4.35Å; M316-F367 HydrophobicContact SD-CE1 4.47Å; M316-F367 HydrophobicContact SD-CG 4.25Å
317	D	98.8	Very high	98.4	Very high	60 Å²	60	34.2 Å²	34.2	32%	0.321	17%	0.167	S	C	.	.	H	α-helix	trans	-61.9	-40.9	176.7	-79.1	-19.5	0	0	0	111.5	V120 T313 S314 T320 L321	V120-D317 HydrophobicContact CG1-CB 3.98Å; V120-D317 HydrophobicContact CG2-CB 3.71Å; T313-D317 PolarHBondContact O-N 2.96Å; S314-D317 PolarHBondContact O-N 3.06Å; D317-T320 PolarHBondContact O-N 2.77Å; D317-L321 WeakPolarHBondContact O-CB 3.5Å; D317-L321 WeakPolarHBondContact O-CD1 3.25Å; D317-L321 VanDerWaalsContact O-CG 3.22Å; D317-L321 WeakPolarHBondContact O-CG 3.38Å; D317-L321 PolarHBondContact O-N 3.47Å
318	I	98.7	Very high	98.4	Very high	4 Å²	4	34.9 Å²	34.9	2%	0.021	17%	0.169	C	C	.	.	H	α-helix	trans	-61.4	-49.2	176.2	-70.8	168.7	0	0	0	110.9	M116 V119 V120 F123 I166 S314 L315 M316 T320 L321 M322	M116-I318 HydrophobicContact CE-CD1 3.34Å; V119-I318 HydrophobicContact CB-CD1 4.17Å; V119-I318 HydrophobicContact CG1-CD1 3.78Å; V119-I318 HydrophobicContact CG1-CG1 4.02Å; V120-I318 HydrophobicContact CG2-CD1 4.34Å; V120-I318 HydrophobicContact CG2-CG1 3.66Å; F123-I318 HydrophobicContact CD2-CG2 4.44Å; F123-I318 HydrophobicContact CE2-CG2 3.98Å; I166-I318 HydrophobicContact CD1-CG2 4.23Å; S314-I318 VanDerWaalsContact O-CG1 3.3Å; S314-I318 WeakPolarHBondContact O-CG1 3.18Å; S314-I318 PolarHBondContact O-N 2.88Å; L315-I318 PolarHBondContact O-N 3.23Å; M316-I318 VanDerWaalsContact C-N 3.33Å; M316-I318 PolarHBondContact O-N 3.32Å; I318-T320 VanDerWaalsContact C-N 3.3Å; I318-T320 PolarHBondContact O-N 3.09Å; I318-L321 PolarHBondContact O-N 3.23Å; I318-M322 HydrophobicContact CG2-CG 4.36Å; I318-M322 WeakPolarHBondContact O-CB 3.2Å; I318-M322 WeakPolarHBondContact O-CG 3.4Å; I318-M322 PolarHBondContact O-N 3.08Å
319	D	98.6	Very high	98.4	Very high	4 Å²	4	36.6 Å²	36.6	2%	0.021	18%	0.176	C	C	.	.	H	α-helix	trans	-59.3	-42.4	176.9	-98.9	-26.3	0	0	0	112.3	L315 M316 T323 K361 V362 F363 F367	L315-D319 PolarHBondContact O-N 3.04Å; M316-D319 PolarHBondContact O-N 2.71Å; D319-T323 WeakPolarHBondContact O-CB 3.45Å; D319-T323 PolarHBondContact O-N 3.17Å; D319-T323 PolarHBondContact O-OG1 2.93Å; D319-K361 HydrophobicContact CB-CG 3.98Å; D319-K361 WeakPolarHBondContact OD2-CG 3.34Å; D319-V362 PolarHBondContact OD1-N 3.37Å; D319-V362 PolarHBondContact OD2-N 3.05Å; D319-V362 VanDerWaalsContact OD2-N 3.16Å; D319-F363 WeakPolarHBondContact OD2-CA 3.39Å; D319-F363 WeakPolarHBondContact OD2-CB 3.09Å; D319-F363 PolarHBondContact OD2-N 2.95Å; D319-F367 HydrophobicContact CB-CE2 4.08Å; D319-F367 HydrophobicContact CB-CZ 4.21Å
320	T	98.6	Very high	98.3	Very high	45 Å²	45	34.1 Å²	34.1	28%	0.276	17%	0.165	S	C	.	.	H	α-helix	trans	-62.5	-46	177.8	-61.9	0	0	0	0	110.7	M316 D317 I318 T323 K324 F367	M316-T320 WeakPolarHBondContact O-CB 3.4Å; M316-T320 PolarHBondContact O-N 3.45Å; M316-T320 PolarHBondContact O-OG1 3.08Å; D317-T320 PolarHBondContact O-N 2.77Å; I318-T320 VanDerWaalsContact C-N 3.3Å; I318-T320 PolarHBondContact O-N 3.09Å; T320-T323 PolarHBondContact O-N 3.32Å; T320-K324 HydrophobicContact CG2-CD 4.23Å; T320-K324 WeakPolarHBondContact O-CG 3.35Å; T320-K324 PolarHBondContact O-N 3.31Å; T320-F367 WeakPolarHBondContact OG1-CZ 3.44Å
321	L	98.7	Very high	98.2	Very high	13 Å²	13	32.4 Å²	32.4	7%	0.068	16%	0.162	C	C	.	.	H	α-helix	trans	-73.3	-37	-177.9	-70.9	165.1	0	0	0	112.8	V120 F123 K124 V127 D317 I318 T323 K324 W325	V120-L321 HydrophobicContact CB-CD1 4.37Å; V120-L321 HydrophobicContact CG1-CD1 3.74Å; V120-L321 WeakPolarHBondContact O-CD1 3.33Å; F123-L321 HydrophobicContact CB-CB 3.76Å; F123-L321 HydrophobicContact CB-CD1 3.88Å; F123-L321 HydrophobicContact CB-CG 4.37Å; F123-L321 HydrophobicContact CG-CB 4.36Å; K124-L321 HydrophobicContact CG-CD1 3.85Å; K124-L321 HydrophobicContact CG-CD2 3.79Å; V127-L321 HydrophobicContact CG2-CD2 4.37Å; D317-L321 WeakPolarHBondContact O-CB 3.5Å; D317-L321 WeakPolarHBondContact O-CD1 3.25Å; D317-L321 VanDerWaalsContact O-CG 3.22Å; D317-L321 WeakPolarHBondContact O-CG 3.38Å; D317-L321 PolarHBondContact O-N 3.47Å; I318-L321 PolarHBondContact O-N 3.23Å; L321-T323 VanDerWaalsContact C-N 3.3Å; L321-T323 PolarHBondContact O-N 2.64Å; L321-K324 HydrophobicContact CD2-CD 4.4Å; L321-K324 PolarHBondContact O-N 3.29Å; L321-W325 WeakPolarHBondContact O-CB 3.3Å; L321-W325 PolarHBondContact O-N 3.15Å
322	M	98.3	Very high	98.1	Very high	8 Å²	8	33 Å²	33	4%	0.039	17%	0.165	C	C	.	.	H	α-helix	trans	-57	-45.6	169.3	-83.3	-81.3	-80	0	0	110.9	F123 L162 E163 I166 I318 W325 R326	F123-M322 HydrophobicContact CE1-CG 3.79Å; F123-M322 HydrophobicContact CE1-SD 3.4Å; F123-M322 WeakPolarHBondContact CE1-SD 3.36Å; F123-M322 HydrophobicContact CE2-CG 4.17Å; F123-M322 HydrophobicContact CE2-SD 4.43Å; F123-M322 HydrophobicContact CZ-CG 3.56Å; F123-M322 HydrophobicContact CZ-SD 3.33Å; F123-M322 WeakPolarHBondContact CZ-SD 3.36Å; L162-M322 HydrophobicContact CD2-SD 4.27Å; E163-M322 HydrophobicContact CG-CE 4.14Å; I166-M322 HydrophobicContact CD1-CE 4.34Å; I318-M322 HydrophobicContact CG2-CG 4.36Å; I318-M322 WeakPolarHBondContact O-CB 3.2Å; I318-M322 WeakPolarHBondContact O-CG 3.4Å; I318-M322 PolarHBondContact O-N 3.08Å; M322-W325 PolarHBondContact O-N 3.19Å; M322-R326 WeakPolarHBondContact O-CG 3.3Å; M322-R326 PolarHBondContact O-N 3.4Å
323	T	98.1	Very high	97.9	Very high	34 Å²	34	33.6 Å²	33.6	21%	0.209	17%	0.169	C	C	.	.	H	α-helix	trans	-64.9	-42.5	176.7	-55.2	0	0	0	0	111.7	D319 T320 L321 R326 Y327 V356	D319-T323 WeakPolarHBondContact O-CB 3.45Å; D319-T323 PolarHBondContact O-N 3.17Å; D319-T323 PolarHBondContact O-OG1 2.93Å; T320-T323 PolarHBondContact O-N 3.32Å; L321-T323 VanDerWaalsContact C-N 3.3Å; L321-T323 PolarHBondContact O-N 2.64Å; T323-R326 PolarHBondContact O-N 3.07Å; T323-Y327 PolarHBondContact O-N 3.44Å; T323-V356 HydrophobicContact CG2-CG1 3.92Å
324	K	98.4	Very high	97.7	Very high	107 Å²	107	35.9 Å²	35.9	47%	0.465	18%	0.176	S	C	.	.	H	α-helix	trans	-62.3	-41.2	174.6	-76.1	175.1	177.8	178.2	0	112.2	V127 T320 L321 R326 Y327 N328	V127-K324 HydrophobicContact CG1-CB 4.46Å; V127-K324 HydrophobicContact CG2-CB 4.13Å; T320-K324 HydrophobicContact CG2-CD 4.23Å; T320-K324 WeakPolarHBondContact O-CG 3.35Å; T320-K324 PolarHBondContact O-N 3.31Å; L321-K324 HydrophobicContact CD2-CD 4.4Å; L321-K324 PolarHBondContact O-N 3.29Å; K324-R326 PolarHBondContact O-N 3.05Å; K324-Y327 PolarHBondContact O-N 2.95Å; K324-N328 PolarHBondContact O-N 3.31Å; K324-N328 PolarHBondContact O-OD1 3.45Å
325	W	98.4	Very high	97.5	Very high	30 Å²	30	40.9 Å²	40.9	11%	0.114	19%	0.194	C	C	.	.	H	α-helix	trans	-60.1	-46.1	175.4	-180	92.5	0	0	0	110.8	Y80 F84 V127 F130 F159 L321 M322 Y327 N328 H329	Y80-W325 AromaticContact CD1-NE1 3.9Å; Y80-W325 AromaticContact CE1-NE1 3.36Å; Y80-W325 AromaticContact CZ-NE1 3.99Å; F84-W325 HydrophobicContact CZ-CZ2 4.03Å; V127-W325 HydrophobicContact CG2-CB 4.03Å; F130-W325 AromaticContact CE2-CD1 3.46Å; F130-W325 VanDerWaalsContact CE2-CD1 3.46Å; F130-W325 HydrophobicContact CE2-CD2 4.28Å; F130-W325 AromaticContact CE2-CG 3.94Å; F130-W325 HydrophobicContact CE2-CG 3.94Å; F130-W325 AromaticContact CE2-NE1 3.49Å; F130-W325 WeakPolarHBondContact CE2-O 3.28Å; F130-W325 HydrophobicContact CZ-CD2 4.32Å; F130-W325 AromaticContact CZ-CE2 3.79Å; F130-W325 HydrophobicContact CZ-CG 4.45Å; F130-W325 HydrophobicContact CZ-CZ2 4.18Å; F130-W325 AromaticContact CZ-NE1 3.6Å; F159-W325 HydrophobicContact CD2-CH2 4.17Å; F159-W325 HydrophobicContact CD2-CZ3 4.24Å; F159-W325 HydrophobicContact CE1-CZ3 4.31Å; F159-W325 AromaticContact CE2-CE3 3.81Å; F159-W325 HydrophobicContact CE2-CE3 3.81Å; F159-W325 AromaticContact CE2-CH2 3.73Å; F159-W325 HydrophobicContact CE2-CH2 3.73Å; F159-W325 HydrophobicContact CE2-CZ2 4.46Å; F159-W325 AromaticContact CE2-CZ3 3.35Å; F159-W325 HydrophobicContact CE2-CZ3 3.35Å; F159-W325 HydrophobicContact CZ-CE3 4.01Å; F159-W325 HydrophobicContact CZ-CH2 4.06Å; F159-W325 AromaticContact CZ-CZ3 3.4Å; F159-W325 HydrophobicContact CZ-CZ3 3.4Å; L321-W325 WeakPolarHBondContact O-CB 3.3Å; L321-W325 PolarHBondContact O-N 3.15Å; M322-W325 PolarHBondContact O-N 3.19Å; W325-Y327 VanDerWaalsContact C-N 3.32Å; W325-Y327 PolarHBondContact O-N 3.14Å; W325-N328 PolarHBondContact O-N 3.27Å; W325-H329 WeakPolarHBondContact O-CB 3.44Å; W325-H329 PolarHBondContact O-N 2.99Å
326	R	97.7	Very high	97.2	Very high	11 Å²	11	41.8 Å²	41.8	4%	0.042	20%	0.199	C	C	.	.	H	α-helix	trans	-60.3	-42	174.2	-68	178.1	-160.8	-83.1	-2.9	112	E163 M322 T323 K324 H329 V330 T355 V356	E163-R326 IonicContact OE1-CZ 3.4Å; E163-R326 VanDerWaalsContact OE1-CZ 3.22Å; E163-R326 IonicContact OE1-NH1 2.73Å; E163-R326 PolarHBondContact OE1-NH1 3.47Å; E163-R326 IonicContact OE1-NH2 3.38Å; E163-R326 PolarHBondContact OE1-NH2 2.91Å; M322-R326 WeakPolarHBondContact O-CG 3.3Å; M322-R326 PolarHBondContact O-N 3.4Å; T323-R326 PolarHBondContact O-N 3.07Å; K324-R326 PolarHBondContact O-N 3.05Å; R326-H329 WeakPolarHBondContact O-CB 3.47Å; R326-H329 PolarHBondContact O-N 3.08Å; R326-V330 VanDerWaalsContact O-CG2 3.24Å; R326-V330 WeakPolarHBondContact O-CG2 3.41Å; R326-V330 PolarHBondContact O-N 3.21Å; R326-T355 WeakPolarHBondContact CD-O 3.45Å; R326-V356 HydrophobicContact CB-CG2 4.07Å
327	Y	97.9	Very high	96.9	Very high	132 Å²	132	41.5 Å²	41.5	52%	0.518	20%	0.198	S	C	.	.	H	α-helix	trans	-68.9	-43.8	-179.3	-173.9	-105.8	0	0	0	112.5	T323 K324 W325 H329 V330 C331 V356	T323-Y327 PolarHBondContact O-N 3.44Å; K324-Y327 PolarHBondContact O-N 2.95Å; W325-Y327 VanDerWaalsContact C-N 3.32Å; W325-Y327 PolarHBondContact O-N 3.14Å; Y327-H329 VanDerWaalsContact C-N 3.3Å; Y327-H329 PolarHBondContact O-N 3.49Å; Y327-V330 WeakPolarHBondContact O-CB 3.34Å; Y327-V330 PolarHBondContact O-N 3.26Å; Y327-V330 VanDerWaalsContact O-N 3.1Å; Y327-C331 PolarHBondContact O-N 2.9Å; Y327-C331 PolarHBondContact O-SG 3.2Å; Y327-C331 VanDerWaalsContact O-SG 3.39Å; Y327-V356 HydrophobicContact CD2-CG1 4.19Å; Y327-V356 HydrophobicContact CD2-CG2 4.39Å
328	N	97.8	Very high	96.6	Very high	50 Å²	50	40 Å²	40	27%	0.267	20%	0.196	S	C	.	.	H	α-helix	trans	-61	-41.7	173.9	-77.8	24.2	0	0	0	111	V127 F130 K324 W325 V330 C331 M332	V127-N328 WeakPolarHBondContact CG1-ND2 3.34Å; V127-N328 PolarHBondContact O-ND2 3.44Å; F130-N328 HydrophobicContact CB-CB 4.5Å; F130-N328 HydrophobicContact CD2-CB 3.51Å; F130-N328 HydrophobicContact CE2-CB 3.91Å; F130-N328 HydrophobicContact CG-CB 4.07Å; K324-N328 PolarHBondContact O-N 3.31Å; K324-N328 PolarHBondContact O-OD1 3.45Å; W325-N328 PolarHBondContact O-N 3.27Å; N328-V330 VanDerWaalsContact C-N 3.34Å; N328-V330 PolarHBondContact O-N 3.07Å; N328-C331 PolarHBondContact O-N 2.93Å; N328-M332 WeakPolarHBondContact O-CB 3.14Å; N328-M332 PolarHBondContact O-N 3.29Å
329	H	96.8	Very high	96.1	Very high	47 Å²	47	45 Å²	45	22%	0.218	23%	0.227	C	C	.	.	H	α-helix	trans	-57.9	-44.8	172	-178	-120.9	0	0	0	112	F130 W325 R326 Y327 C331 M332 V333	F130-H329 HydrophobicContact CE1-CB 3.94Å; F130-H329 HydrophobicContact CE2-CB 4.37Å; F130-H329 HydrophobicContact CZ-CB 3.58Å; W325-H329 WeakPolarHBondContact O-CB 3.44Å; W325-H329 PolarHBondContact O-N 2.99Å; R326-H329 WeakPolarHBondContact O-CB 3.47Å; R326-H329 PolarHBondContact O-N 3.08Å; Y327-H329 VanDerWaalsContact C-N 3.3Å; Y327-H329 PolarHBondContact O-N 3.49Å; H329-C331 PolarHBondContact O-N 3.48Å; H329-M332 PolarHBondContact O-N 2.97Å; H329-V333 WeakPolarHBondContact O-CB 3.27Å; H329-V333 VanDerWaalsContact O-CG2 3.25Å; H329-V333 WeakPolarHBondContact O-CG2 3.28Å; H329-V333 PolarHBondContact O-N 3.05Å
330	V	96.2	Very high	95.5	Very high	4 Å²	4	50.4 Å²	50.4	2%	0.024	25%	0.25	C	S	.	.	H	α-helix	trans	-58.8	-46.5	175.6	167.6	0	0	0	0	111.6	R326 Y327 N328 V333 H334 Y349 L352 R353 V356	R326-V330 VanDerWaalsContact O-CG2 3.24Å; R326-V330 WeakPolarHBondContact O-CG2 3.41Å; R326-V330 PolarHBondContact O-N 3.21Å; Y327-V330 WeakPolarHBondContact O-CB 3.34Å; Y327-V330 PolarHBondContact O-N 3.26Å; Y327-V330 VanDerWaalsContact O-N 3.1Å; N328-V330 VanDerWaalsContact C-N 3.34Å; N328-V330 PolarHBondContact O-N 3.07Å; V330-V333 PolarHBondContact O-N 3.48Å; V330-H334 WeakPolarHBondContact O-CB 3.41Å; V330-H334 PolarHBondContact O-N 3.15Å; V330-Y349 HydrophobicContact CG1-CD2 3.81Å; V330-Y349 HydrophobicContact CG1-CE2 3.5Å; V330-Y349 VanDerWaalsContact CG1-CE2 3.5Å; V330-L352 VanDerWaalsContact CG2-C 3.41Å; V330-L352 HydrophobicContact CG2-CB 3.51Å; V330-R353 HydrophobicContact CG1-CB 4.31Å; V330-V356 HydrophobicContact CG2-CG2 4.05Å
331	C	96.9	Very high	95	Very high	51 Å²	51	51.1 Å²	51.1	35%	0.345	26%	0.261	S	S	.	.	H	α-helix	trans	-62.5	-47.2	179.7	-69.4	0	0	0	0	111.7	Y327 N328 H329 H334 R335	Y327-C331 PolarHBondContact O-N 2.9Å; Y327-C331 PolarHBondContact O-SG 3.2Å; Y327-C331 VanDerWaalsContact O-SG 3.39Å; N328-C331 PolarHBondContact O-N 2.93Å; H329-C331 PolarHBondContact O-N 3.48Å; C331-H334 PolarHBondContact O-N 2.9Å; C331-R335 PolarHBondContact O-N 3.4Å
332	M	96.7	Very high	94.3	Very high	15 Å²	15	51.2 Å²	51.2	7%	0.074	27%	0.265	C	S	.	.	H	α-helix	trans	-59.6	-49.1	175.3	-178.8	-164.5	73.2	0	0	111	F130 L133 E134 N328 H329 H334 R335 M336	F130-M332 HydrophobicContact CD1-CE 4.31Å; F130-M332 HydrophobicContact CD1-SD 3.74Å; F130-M332 HydrophobicContact CE1-CE 4.11Å; F130-M332 HydrophobicContact CE1-SD 4.15Å; L133-M332 HydrophobicContact CB-SD 4.25Å; L133-M332 HydrophobicContact CD2-CE 4.12Å; L133-M332 HydrophobicContact CD2-SD 3.62Å; L133-M332 HydrophobicContact CG-SD 3.98Å; E134-M332 HydrophobicContact CG-CB 4.42Å; E134-M332 HydrophobicContact CG-CG 4.14Å; N328-M332 WeakPolarHBondContact O-CB 3.14Å; N328-M332 PolarHBondContact O-N 3.29Å; H329-M332 PolarHBondContact O-N 2.97Å; M332-H334 VanDerWaalsContact C-N 3.3Å; M332-H334 PolarHBondContact O-N 3.39Å; M332-R335 WeakPolarHBondContact O-CB 3.35Å; M332-R335 PolarHBondContact O-N 2.94Å; M332-R335 VanDerWaalsContact O-N 3.11Å; M332-M336 HydrophobicContact CG-CG 4.35Å; M332-M336 WeakPolarHBondContact O-CG 3.39Å; M332-M336 PolarHBondContact O-N 3.18Å
333	V	94.1	Very high	93.4	Very high	13 Å²	13	52.7 Å²	52.7	8%	0.079	27%	0.274	C	S	.	.	H	α-helix	trans	-62.9	-36.6	179.9	170.3	0	0	0	0	111.8	H329 V330 R335 M336 L337 L352	H329-V333 WeakPolarHBondContact O-CB 3.27Å; H329-V333 VanDerWaalsContact O-CG2 3.25Å; H329-V333 WeakPolarHBondContact O-CG2 3.28Å; H329-V333 PolarHBondContact O-N 3.05Å; V330-V333 PolarHBondContact O-N 3.48Å; V333-R335 VanDerWaalsContact C-N 3.28Å; V333-R335 PolarHBondContact O-N 3.25Å; V333-M336 PolarHBondContact O-N 3.17Å; V333-L337 HydrophobicContact CG1-CB 4.39Å; V333-L337 HydrophobicContact CG1-CD1 3.88Å; V333-L337 HydrophobicContact CG1-CG 4.26Å; V333-L337 WeakPolarHBondContact O-CB 3.47Å; V333-L337 PolarHBondContact O-N 2.89Å; V333-L352 HydrophobicContact CB-CD1 3.91Å; V333-L352 HydrophobicContact CG1-CD1 3.76Å; V333-L352 HydrophobicContact CG2-CD1 3.79Å
334	H	95.3	Very high	92.5	Very high	90 Å²	90	52.1 Å²	52.1	42%	0.417	28%	0.275	S	S	.	.	H	α-helix	trans	-60.2	-41	175.1	-169.6	-158.4	0	0	0	111.5	V330 C331 M332 G338 Y349	V330-H334 WeakPolarHBondContact O-CB 3.41Å; V330-H334 PolarHBondContact O-N 3.15Å; C331-H334 PolarHBondContact O-N 2.9Å; M332-H334 VanDerWaalsContact C-N 3.3Å; M332-H334 PolarHBondContact O-N 3.39Å; H334-G338 VanDerWaalsContact O-CA 3.24Å; H334-G338 WeakPolarHBondContact O-CA 3.48Å; H334-G338 PolarHBondContact O-N 3.09Å; H334-Y349 HydrophobicContact CB-CD2 3.58Å; H334-Y349 HydrophobicContact CB-CE2 3.72Å; H334-Y349 HydrophobicContact CB-CG 4.42Å; H334-Y349 AromaticContact CG-CD2 3.81Å; H334-Y349 AromaticContact CG-CE2 3.71Å; H334-Y349 AromaticContact ND1-CE2 3.97Å
335	R	94.3	Very high	91.6	Very high	110 Å²	110	49.1 Å²	49.1	42%	0.415	28%	0.275	S	S	.	.	H	α-helix	trans	-68.2	-39.4	175	-175.7	166.6	60.8	97.9	-0.5	112.6	E134 M136 A138 C331 M332 V333	E134-R335 VanDerWaalsContact C-NH2 3.33Å; E134-R335 VanDerWaalsContact CG-NH2 3.27Å; E134-R335 PolarHBondContact O-NH1 2.75Å; E134-R335 VanDerWaalsContact O-NH1 3.15Å; E134-R335 PolarHBondContact O-NH2 3.5Å; M136-R335 PolarHBondContact O-NH1 3.28Å; A138-R335 WeakPolarHBondContact CB-O 3.26Å; C331-R335 PolarHBondContact O-N 3.4Å; M332-R335 WeakPolarHBondContact O-CB 3.35Å; M332-R335 PolarHBondContact O-N 2.94Å; M332-R335 VanDerWaalsContact O-N 3.11Å; V333-R335 VanDerWaalsContact C-N 3.28Å; V333-R335 PolarHBondContact O-N 3.25Å
336	M	93	Very high	90.8	Very high	20 Å²	20	48 Å²	48	10%	0.099	27%	0.272	C	S	.	.	H	α-helix	trans	-76.9	-35	-177.1	-65.2	-61.4	-178.3	0	0	113.8	M136 A138 F141 M332 V333	M136-M336 HydrophobicContact CB-CE 4.21Å; M136-M336 HydrophobicContact CE-CE 3.81Å; M136-M336 HydrophobicContact CE-SD 4.31Å; M136-M336 HydrophobicContact CG-CE 4.4Å; M136-M336 VanDerWaalsContact O-CE 3.27Å; M136-M336 WeakPolarHBondContact O-CE 3.1Å; A138-M336 HydrophobicContact CB-SD 4.39Å; F141-M336 HydrophobicContact CB-SD 3.98Å; F141-M336 HydrophobicContact CD1-CB 4Å; F141-M336 HydrophobicContact CD1-SD 4.38Å; F141-M336 HydrophobicContact CE1-CB 4.25Å; F141-M336 HydrophobicContact CG-SD 4.22Å; M332-M336 HydrophobicContact CG-CG 4.35Å; M332-M336 WeakPolarHBondContact O-CG 3.39Å; M332-M336 PolarHBondContact O-N 3.18Å; V333-M336 PolarHBondContact O-N 3.17Å
337	L	91.1	Very high	90.1	Very high	24 Å²	24	50.4 Å²	50.4	13%	0.126	29%	0.29	C	S	.	.	H	α-helix	trans	-118.8	-18	-171.5	-63.4	-174.5	0	0	0	114.6	F141 V333 T339 K340	F141-L337 HydrophobicContact CE1-CD2 3.76Å; V333-L337 HydrophobicContact CG1-CB 4.39Å; V333-L337 HydrophobicContact CG1-CD1 3.88Å; V333-L337 HydrophobicContact CG1-CG 4.26Å; V333-L337 WeakPolarHBondContact O-CB 3.47Å; V333-L337 PolarHBondContact O-N 2.89Å; L337-T339 PolarHBondContact O-N 2.94Å; L337-K340 HydrophobicContact CB-CB 4.47Å; L337-K340 VanDerWaalsContact O-CB 3.29Å; L337-K340 WeakPolarHBondContact O-CB 3.13Å; L337-K340 WeakPolarHBondContact O-CG 3.34Å; L337-K340 PolarHBondContact O-N 3.22Å
338	G	92.8	Very high	89.6	Confident	27 Å²	27	44.2 Å²	44.2	28%	0.278	27%	0.267	S	S	.	.	T	Hydrogen-bonded Turn	trans	56	-121.6	-167.5	0	0	0	0	0	110.8	H334	H334-G338 VanDerWaalsContact O-CA 3.24Å; H334-G338 WeakPolarHBondContact O-CA 3.48Å; H334-G338 PolarHBondContact O-N 3.09Å
339	T	89.6	Confident	89.2	Confident	111 Å²	111	43.2 Å²	43.2	68%	0.681	26%	0.259	S	S	*	.	T	Hydrogen-bonded Turn	trans	-98.2	4.9	177.7	55.1	0	0	0	0	113.9	L337	L337-T339 PolarHBondContact O-N 2.94Å
340	K	85.9	Confident	88.8	Confident	116 Å²	116	46.2 Å²	46.2	50%	0.504	27%	0.273	S	S	.	.	P	Polyproline II helix	trans	-63.3	145.2	178.9	-66.5	177.3	179	177.6	0	110.8	L337	L337-K340 HydrophobicContact CB-CB 4.47Å; L337-K340 VanDerWaalsContact O-CB 3.29Å; L337-K340 WeakPolarHBondContact O-CB 3.13Å; L337-K340 WeakPolarHBondContact O-CG 3.34Å; L337-K340 PolarHBondContact O-N 3.22Å
341	A	87.5	Confident	88.5	Confident	61 Å²	61	47.1 Å²	47.1	50%	0.504	28%	0.276	S	S	.	.	P	Polyproline II helix	trans	-62.1	145.9	171.3	0	0	0	0	0	111.3	R145 S346	R145-A341 PolarHBondContact NH2-O 2.86Å; A341-S346 WeakPolarHBondContact CA-O 3.41Å; A341-S346 WeakPolarHBondContact CB-O 3.46Å
342	G	83.3	Confident	88.3	Confident	14 Å²	14	46 Å²	46	14%	0.144	27%	0.267	C	S	.	.	P	Polyproline II helix	trans	-72.3	157.9	176.7	0	0	0	0	0	112.3	G344 G345 S346	G342-G344 PolarHBondContact O-N 3.04Å; G342-G345 PolarHBondContact O-N 3.03Å; G342-S346 PolarHBondContact N-O 3.3Å
343	T	80.8	Confident	88.2	Confident	39 Å²	39	52.5 Å²	52.5	24%	0.239	29%	0.291	C	S	.	.	T	Hydrogen-bonded Turn	trans	-61.5	-31.2	175.8	49.9	0	0	0	0	112.5	R145 A151 G345	R145-T343 HydrophobicContact CG-CG2 4.43Å; A151-T343 PolarHBondContact O-OG1 3.49Å; T343-G345 PolarHBondContact O-N 3.44Å
344	G	77.9	Confident	88.2	Confident	22 Å²	22	53.9 Å²	53.9	23%	0.227	30%	0.301	C	S	.	.	T	Hydrogen-bonded Turn	trans	-76.3	8.4	172.2	0	0	0	0	0	114.9	S152 Y176 G342 S346	S152-G344 WeakPolarHBondContact OG-CA 3.31Å; Y176-G344 PolarHBondContact OH-O 3.38Å; G342-G344 PolarHBondContact O-N 3.04Å; G344-S346 PolarHBondContact O-N 3.42Å
345	G	79.2	Confident	88.1	Confident	44 Å²	44	50 Å²	50	45%	0.454	28%	0.283	S	S	.	.	S	Bend	trans	84.6	-1	174.9	0	0	0	0	0	116.1	Y176 G342 T343	Y176-G345 VanDerWaalsContact CZ-C 3.49Å; Y176-G345 WeakPolarHBondContact OH-CA 3.25Å; Y176-G345 PolarHBondContact OH-O 2.91Å; G342-G345 PolarHBondContact O-N 3.03Å; T343-G345 PolarHBondContact O-N 3.44Å
346	S	82.3	Confident	88.2	Confident	7 Å²	7	46.9 Å²	46.9	5%	0.049	28%	0.276	C	S	.	.	S	Bend	trans	-73.7	166.9	179	74.3	0	0	0	0	112	Y176 A341 G342 G344 G348	Y176-S346 PolarHBondContact OH-N 3.02Å; A341-S346 WeakPolarHBondContact CA-O 3.41Å; A341-S346 WeakPolarHBondContact CB-O 3.46Å; G342-S346 PolarHBondContact N-O 3.3Å; G344-S346 PolarHBondContact O-N 3.42Å; S346-G348 PolarHBondContact O-N 3.32Å; S346-G348 PolarHBondContact OG-N 3.35Å; S346-G348 VanDerWaalsContact OG-N 3.16Å
347	S	82.9	Confident	88.3	Confident	61 Å²	61	48 Å²	48	43%	0.427	29%	0.286	S	S	.	.			trans	-64.3	9.7	167.6	57.6	0	0	0	0	113.2	Y349 Y351	S347-Y349 PolarHBondContact O-N 2.95Å; S347-Y351 PolarHBondContact OG-N 3.41Å
348	G	87.1	Confident	88.6	Confident	3 Å²	3	51 Å²	51	3%	0.031	30%	0.302	C	S	.	.	T	Hydrogen-bonded Turn	trans	65.8	-114.5	176	0	0	0	0	0	110.6	S346 H350 Y351 L352	S346-G348 PolarHBondContact O-N 3.32Å; S346-G348 PolarHBondContact OG-N 3.35Å; S346-G348 VanDerWaalsContact OG-N 3.16Å; G348-H350 VanDerWaalsContact C-N 3.33Å; G348-H350 PolarHBondContact O-N 3.03Å; G348-Y351 PolarHBondContact O-N 3.34Å; G348-L352 WeakPolarHBondContact O-CG 3.33Å; G348-L352 PolarHBondContact O-N 3.01Å; G348-L352 VanDerWaalsContact O-N 3.15Å
349	Y	89	Confident	88.7	Confident	29 Å²	29	55.7 Å²	55.7	11%	0.114	31%	0.312	C	S	.	.	H	α-helix	trans	-50.4	-46.3	-179.5	168.5	-106.7	0	0	0	113.7	V330 H334 S347 Y351 L352 R353	V330-Y349 HydrophobicContact CG1-CD2 3.81Å; V330-Y349 HydrophobicContact CG1-CE2 3.5Å; V330-Y349 VanDerWaalsContact CG1-CE2 3.5Å; H334-Y349 HydrophobicContact CB-CD2 3.58Å; H334-Y349 HydrophobicContact CB-CE2 3.72Å; H334-Y349 HydrophobicContact CB-CG 4.42Å; H334-Y349 AromaticContact CG-CD2 3.81Å; H334-Y349 AromaticContact CG-CE2 3.71Å; H334-Y349 AromaticContact ND1-CE2 3.97Å; S347-Y349 PolarHBondContact O-N 2.95Å; Y349-Y351 PolarHBondContact O-N 2.93Å; Y349-L352 PolarHBondContact O-N 3.02Å; Y349-R353 WeakPolarHBondContact O-CB 3.46Å; Y349-R353 PolarHBondContact O-N 3.22Å; Y349-R353 PolarHBondContact OH-NH1 3.2Å
350	H	88.8	Confident	89	Confident	110 Å²	110	50.9 Å²	50.9	51%	0.509	28%	0.281	S	S	.	.	H	α-helix	trans	-66.9	-40.8	-175.2	-70.6	-67.4	0	0	0	112.8	G348 S354	G348-H350 VanDerWaalsContact C-N 3.33Å; G348-H350 PolarHBondContact O-N 3.03Å; H350-S354 PolarHBondContact O-N 3.45Å
351	Y	90.6	Very high	89.6	Confident	23 Å²	23	47 Å²	47	9%	0.09	26%	0.264	C	S	.	.	H	α-helix	trans	-61.4	-50.8	173.3	168.8	-96.1	0	0	0	110.6	F154 S347 G348 Y349 R353 S354 T355	F154-Y351 HydrophobicContact CE1-CD1 4.14Å; F154-Y351 AromaticContact CE1-CE1 3.32Å; F154-Y351 HydrophobicContact CE1-CE1 3.32Å; F154-Y351 HydrophobicContact CE1-CE2 4.5Å; F154-Y351 AromaticContact CE1-CZ 3.54Å; F154-Y351 AromaticContact CZ-CD1 3.6Å; F154-Y351 HydrophobicContact CZ-CD1 3.6Å; F154-Y351 AromaticContact CZ-CE1 3.28Å; F154-Y351 HydrophobicContact CZ-CE1 3.28Å; F154-Y351 HydrophobicContact CZ-CG 4.37Å; F154-Y351 AromaticContact CZ-CZ 3.81Å; S347-Y351 PolarHBondContact OG-N 3.41Å; G348-Y351 PolarHBondContact O-N 3.34Å; Y349-Y351 PolarHBondContact O-N 2.93Å; Y351-R353 VanDerWaalsContact C-N 3.28Å; Y351-R353 PolarHBondContact O-N 2.95Å; Y351-S354 WeakPolarHBondContact O-CB 3.4Å; Y351-S354 PolarHBondContact O-N 2.87Å; Y351-S354 PolarHBondContact O-OG 3.49Å; Y351-T355 HydrophobicContact CE1-CG2 3.95Å; Y351-T355 HydrophobicContact CE2-CG2 4.45Å; Y351-T355 PolarHBondContact O-N 3.3Å
352	L	92.1	Very high	90.1	Very high	27 Å²	27	44.2 Å²	44.2	14%	0.141	24%	0.241	C	C	.	.	H	α-helix	trans	-59.8	-40.8	-178	-66	172.6	0	0	0	111.5	V330 V333 G348 Y349 S354 T355	V330-L352 VanDerWaalsContact CG2-C 3.41Å; V330-L352 HydrophobicContact CG2-CB 3.51Å; V333-L352 HydrophobicContact CB-CD1 3.91Å; V333-L352 HydrophobicContact CG1-CD1 3.76Å; V333-L352 HydrophobicContact CG2-CD1 3.79Å; G348-L352 WeakPolarHBondContact O-CG 3.33Å; G348-L352 PolarHBondContact O-N 3.01Å; G348-L352 VanDerWaalsContact O-N 3.15Å; Y349-L352 PolarHBondContact O-N 3.02Å; L352-S354 VanDerWaalsContact C-N 3.28Å; L352-S354 PolarHBondContact O-N 3.45Å; L352-T355 WeakPolarHBondContact O-CB 3.31Å; L352-T355 PolarHBondContact O-N 3.11Å; L352-T355 PolarHBondContact O-OG1 3.2Å
353	R	94.6	Very high	90.9	Very high	152 Å²	152	43.6 Å²	43.6	57%	0.574	23%	0.234	S	C	*	.	H	α-helix	trans	-59.4	-37.3	175.5	-175	174.9	175.4	157.3	-3	112.4	V330 Y349 Y351 T355 V356	V330-R353 HydrophobicContact CG1-CB 4.31Å; Y349-R353 WeakPolarHBondContact O-CB 3.46Å; Y349-R353 PolarHBondContact O-N 3.22Å; Y349-R353 PolarHBondContact OH-NH1 3.2Å; Y351-R353 VanDerWaalsContact C-N 3.28Å; Y351-R353 PolarHBondContact O-N 2.95Å; R353-T355 PolarHBondContact O-N 2.85Å; R353-V356 WeakPolarHBondContact O-CB 3.47Å; R353-V356 PolarHBondContact O-N 2.96Å; R353-V356 VanDerWaalsContact O-N 3.13Å
354	S	93.8	Very high	91.7	Very high	42 Å²	42	42.1 Å²	42.1	29%	0.294	23%	0.225	S	C	.	.	H	α-helix	trans	-65.9	-21.9	176.3	78.1	0	0	0	0	113.6	V174 H350 Y351 L352 V356	V174-S354 WeakPolarHBondContact CG1-OG 3.41Å; H350-S354 PolarHBondContact O-N 3.45Å; Y351-S354 WeakPolarHBondContact O-CB 3.4Å; Y351-S354 PolarHBondContact O-N 2.87Å; Y351-S354 PolarHBondContact O-OG 3.49Å; L352-S354 VanDerWaalsContact C-N 3.28Å; L352-S354 PolarHBondContact O-N 3.45Å; S354-V356 VanDerWaalsContact C-N 3.28Å
355	T	93.9	Very high	92.7	Very high	8 Å²	8	41.1 Å²	41.1	5%	0.049	22%	0.215	C	C	.	.	T	Hydrogen-bonded Turn	trans	-78.1	-13.2	175.5	75.3	0	0	0	0	113.3	R326 Y351 L352 R353 S357 Y360	R326-T355 WeakPolarHBondContact CD-O 3.45Å; Y351-T355 HydrophobicContact CE1-CG2 3.95Å; Y351-T355 HydrophobicContact CE2-CG2 4.45Å; Y351-T355 PolarHBondContact O-N 3.3Å; L352-T355 WeakPolarHBondContact O-CB 3.31Å; L352-T355 PolarHBondContact O-N 3.11Å; L352-T355 PolarHBondContact O-OG1 3.2Å; R353-T355 PolarHBondContact O-N 2.85Å; T355-S357 VanDerWaalsContact C-N 3.26Å; T355-S357 PolarHBondContact O-N 3.44Å; T355-S357 VanDerWaalsContact O-N 3.09Å; T355-Y360 HydrophobicContact CG2-CE2 4.2Å; T355-Y360 VanDerWaalsContact O-CD2 3.3Å; T355-Y360 WeakPolarHBondContact O-CD2 3.41Å
356	V	96.8	Very high	93.6	Very high	45 Å²	45	39.1 Å²	39.1	27%	0.273	19%	0.193	S	C	.	.	S	Bend	trans	-85.1	73.6	172.5	-171	0	0	0	0	108.1	T323 R326 Y327 V330 R353 S354	T323-V356 HydrophobicContact CG2-CG1 3.92Å; R326-V356 HydrophobicContact CB-CG2 4.07Å; Y327-V356 HydrophobicContact CD2-CG1 4.19Å; Y327-V356 HydrophobicContact CD2-CG2 4.39Å; V330-V356 HydrophobicContact CG2-CG2 4.05Å; R353-V356 WeakPolarHBondContact O-CB 3.47Å; R353-V356 PolarHBondContact O-N 2.96Å; R353-V356 VanDerWaalsContact O-N 3.13Å; S354-V356 VanDerWaalsContact C-N 3.28Å
357	S	95.1	Very high	94.4	Very high	43 Å²	43	41.3 Å²	41.3	30%	0.301	20%	0.202	S	C	.	.	S	Bend	trans	-151.1	153.5	-174.4	175.7	0	0	0	0	110.6	T355 R359 Y360	T355-S357 VanDerWaalsContact C-N 3.26Å; T355-S357 PolarHBondContact O-N 3.44Å; T355-S357 VanDerWaalsContact O-N 3.09Å; S357-R359 PolarHBondContact O-N 2.95Å; S357-R359 PolarHBondContact OG-N 3.38Å; S357-Y360 PolarHBondContact O-N 3.45Å
358	D	96.3	Very high	95	Very high	86 Å²	86	42 Å²	42	46%	0.46	20%	0.201	S	C	.	.	G	3₁₀ helix	trans	-60.9	-11.7	175	-67.2	-26.1	0	0	0	113.7	Y360 K361 V364	D358-Y360 PolarHBondContact O-N 2.91Å; D358-K361 PolarHBondContact O-N 3.46Å; D358-K361 VanDerWaalsContact O-N 3.12Å; D358-K361 VanDerWaalsContact OD1-CE 3.27Å; D358-K361 WeakPolarHBondContact OD1-CE 3.37Å; D358-K361 IonicContact OD1-NZ 2.76Å; D358-K361 PolarHBondContact OD1-NZ 3.49Å; D358-V364 HydrophobicContact CB-CG2 4.41Å
359	R	95.1	Very high	95.5	Very high	127 Å²	127	41.9 Å²	41.9	48%	0.479	20%	0.2	S	C	.	.	G	3₁₀ helix	trans	-55.2	-32.6	167.2	-70.5	179.8	176.6	-115.7	-1.5	113.1	L172 S357	L172-R359 HydrophobicContact CB-CB 4.47Å; S357-R359 PolarHBondContact O-N 2.95Å; S357-R359 PolarHBondContact OG-N 3.38Å
360	Y	96.9	Very high	95.8	Very high	9 Å²	9	43.8 Å²	43.8	4%	0.035	22%	0.217	C	C	.	.	G	3₁₀ helix	trans	-98.9	0.6	179.3	-70.3	-90.5	0	0	0	113.4	V168 R173 V174 T355 S357 D358	V168-Y360 HydrophobicContact CG1-CD1 3.78Å; V168-Y360 HydrophobicContact CG1-CE1 4.16Å; R173-Y360 HydrophobicContact CG-CE1 4.24Å; V174-Y360 HydrophobicContact CG2-CE2 4.11Å; V174-Y360 PolarHBondContact N-OH 3.29Å; T355-Y360 HydrophobicContact CG2-CE2 4.2Å; T355-Y360 VanDerWaalsContact O-CD2 3.3Å; T355-Y360 WeakPolarHBondContact O-CD2 3.41Å; S357-Y360 PolarHBondContact O-N 3.45Å; D358-Y360 PolarHBondContact O-N 2.91Å
361	K	98.1	Very high	96.1	Very high	35 Å²	35	42.2 Å²	42.2	15%	0.152	22%	0.215	C	C	.	.			trans	-86.8	109.4	176.6	-173.3	-179.7	-77.4	163.1	0	108.6	D319 D358 V364 F367	D319-K361 HydrophobicContact CB-CG 3.98Å; D319-K361 WeakPolarHBondContact OD2-CG 3.34Å; D358-K361 PolarHBondContact O-N 3.46Å; D358-K361 VanDerWaalsContact O-N 3.12Å; D358-K361 VanDerWaalsContact OD1-CE 3.27Å; D358-K361 WeakPolarHBondContact OD1-CE 3.37Å; D358-K361 IonicContact OD1-NZ 2.76Å; D358-K361 PolarHBondContact OD1-NZ 3.49Å; K361-V364 HydrophobicContact CB-CB 4.27Å; K361-V364 HydrophobicContact CD-CB 3.96Å; K361-V364 HydrophobicContact CD-CG2 3.99Å; K361-V364 HydrophobicContact CG-CB 4.02Å; K361-F367 HydrophobicContact CD-CD2 3.76Å; K361-F367 HydrophobicContact CD-CE2 3.72Å; K361-F367 HydrophobicContact CD-CG 4.4Å; K361-F367 HydrophobicContact CD-CZ 4.32Å; K361-F367 HydrophobicContact CG-CD2 4.41Å; K361-F367 HydrophobicContact CG-CE2 4.06Å
362	V	98.3	Very high	96.3	Very high	3 Å²	3	42.3 Å²	42.3	2%	0.018	22%	0.216	C	C	.	.	T	Hydrogen-bonded Turn	trans	-77.3	-39.2	-169.5	176.9	0	0	0	0	111.6	I166 V168 L203 R284 D319	I166-V362 HydrophobicContact CG2-CB 3.95Å; I166-V362 HydrophobicContact CG2-CG1 4.08Å; I166-V362 HydrophobicContact CG2-CG2 3.81Å; V168-V362 HydrophobicContact CB-CG2 4.49Å; V168-V362 HydrophobicContact CG2-CG2 3.66Å; L203-V362 HydrophobicContact CB-CG1 3.73Å; L203-V362 HydrophobicContact CD1-CG1 4.22Å; L203-V362 HydrophobicContact CD2-CG1 3.94Å; L203-V362 HydrophobicContact CG-CG1 4.16Å; R284-V362 WeakPolarHBondContact CG-O 3.36Å; D319-V362 PolarHBondContact OD1-N 3.37Å; D319-V362 PolarHBondContact OD2-N 3.05Å; D319-V362 VanDerWaalsContact OD2-N 3.16Å
363	F	98.5	Very high	96.5	Very high	1 Å²	1	45.1 Å²	45.1	0%	0.004	23%	0.231	C	C	.	.	T	Hydrogen-bonded Turn	trans	-101.3	35.9	179.3	-57.8	-78.8	0	0	0	111.8	I166 L202 L203 V206 L315 D319 D365 L366 F367	I166-F363 HydrophobicContact CG2-CE2 4.01Å; L202-F363 HydrophobicContact CD2-CE2 4.34Å; L202-F363 HydrophobicContact CD2-CZ 4.03Å; L202-F363 HydrophobicContact CG-CZ 4.09Å; L203-F363 HydrophobicContact CB-CE1 4.43Å; L203-F363 HydrophobicContact CD1-CD1 4.05Å; L203-F363 HydrophobicContact CD1-CE1 3.94Å; V206-F363 HydrophobicContact CB-CE1 4.34Å; V206-F363 HydrophobicContact CG1-CE1 4.36Å; V206-F363 HydrophobicContact CG2-CE1 4.48Å; L315-F363 HydrophobicContact CB-CD1 4.37Å; L315-F363 HydrophobicContact CB-CD2 3.9Å; L315-F363 HydrophobicContact CB-CE2 4.12Å; L315-F363 HydrophobicContact CB-CG 4.04Å; L315-F363 HydrophobicContact CB-CZ 4.45Å; L315-F363 HydrophobicContact CD1-CD1 4.15Å; L315-F363 HydrophobicContact CD1-CE1 3.88Å; L315-F363 HydrophobicContact CD1-CZ 4.15Å; L315-F363 HydrophobicContact CD2-CE1 4.38Å; L315-F363 HydrophobicContact CD2-CE2 3.86Å; L315-F363 HydrophobicContact CD2-CZ 3.79Å; L315-F363 HydrophobicContact CG-CE1 4.5Å; L315-F363 HydrophobicContact CG-CE2 4.41Å; L315-F363 HydrophobicContact CG-CZ 4.34Å; D319-F363 WeakPolarHBondContact OD2-CA 3.39Å; D319-F363 WeakPolarHBondContact OD2-CB 3.09Å; D319-F363 PolarHBondContact OD2-N 2.95Å; F363-D365 PolarHBondContact O-N 3.48Å; F363-D365 VanDerWaalsContact O-N 3.1Å; F363-L366 HydrophobicContact CB-CD1 3.86Å; F363-L366 HydrophobicContact CB-CG 4.09Å; F363-L366 HydrophobicContact CD1-CD1 4.26Å; F363-L366 HydrophobicContact CG-CD1 4.3Å; F363-L366 WeakPolarHBondContact O-CB 3.23Å; F363-L366 PolarHBondContact O-N 2.87Å; F363-F367 WeakPolarHBondContact O-CD2 3.26Å
364	V	98.5	Very high	96.5	Very high	7 Å²	7	38.7 Å²	38.7	4%	0.042	21%	0.208	C	C	.	.	H	α-helix	trans	-52.6	-34	-179.3	65.4	0	0	0	0	112.9	R284 D358 K361 L366 F367 N368	R284-V364 HydrophobicContact CG-CG1 3.86Å; D358-V364 HydrophobicContact CB-CG2 4.41Å; K361-V364 HydrophobicContact CB-CB 4.27Å; K361-V364 HydrophobicContact CD-CB 3.96Å; K361-V364 HydrophobicContact CD-CG2 3.99Å; K361-V364 HydrophobicContact CG-CB 4.02Å; V364-L366 VanDerWaalsContact C-N 3.31Å; V364-L366 PolarHBondContact O-N 2.66Å; V364-F367 WeakPolarHBondContact O-CB 3.38Å; V364-F367 PolarHBondContact O-N 2.84Å; V364-N368 PolarHBondContact O-N 3.41Å; V364-N368 VanDerWaalsContact O-N 3.14Å
365	D	98.3	Very high	96.6	Very high	2 Å²	2	39.1 Å²	39.1	1%	0.011	21%	0.21	C	C	.	.	H	α-helix	trans	-61	-37.9	178.3	-63.1	-46.2	0	0	0	112.5	R283 R284 L285 L290 F363 F367 N368 L369	R283-D365 VanDerWaalsContact CA-OD1 3.28Å; R283-D365 WeakPolarHBondContact CA-OD1 3.49Å; R283-D365 VanDerWaalsContact CB-OD1 3.3Å; R283-D365 WeakPolarHBondContact CB-OD1 3.45Å; R283-D365 VanDerWaalsContact CG-OD1 3.3Å; R283-D365 WeakPolarHBondContact CG-OD1 3.35Å; R284-D365 VanDerWaalsContact CA-OD2 3.31Å; R284-D365 WeakPolarHBondContact CA-OD2 3.35Å; R284-D365 WeakPolarHBondContact CB-OD2 3.41Å; R284-D365 PolarHBondContact N-OD2 2.84Å; L285-D365 HydrophobicContact CD1-CB 3.99Å; L285-D365 HydrophobicContact CG-CB 4.29Å; L285-D365 PolarHBondContact N-OD2 2.58Å; L290-D365 HydrophobicContact CD1-CB 3.91Å; F363-D365 PolarHBondContact O-N 3.48Å; F363-D365 VanDerWaalsContact O-N 3.1Å; D365-F367 VanDerWaalsContact C-N 3.25Å; D365-F367 PolarHBondContact O-N 2.83Å; D365-N368 CarbonylContact O-C 3.44Å; D365-N368 PolarHBondContact O-N 3.49Å; D365-N368 VanDerWaalsContact O-N 3.1Å; D365-L369 WeakPolarHBondContact O-CG 3.35Å; D365-L369 PolarHBondContact O-N 3.35Å
366	L	98.5	Very high	96.5	Very high	1 Å²	1	45.9 Å²	45.9	1%	0.005	23%	0.234	C	C	.	.	H	α-helix	trans	-63.3	-32.7	179.8	-60.3	-175	0	0	0	112.3	L285 A293 Y297 L312 L315 M316 F363 V364 L369	L285-L366 HydrophobicContact CD1-CD2 4.18Å; A293-L366 HydrophobicContact CB-CD2 3.88Å; Y297-L366 PolarHBondContact OH-O 3.47Å; L312-L366 HydrophobicContact CB-CD1 4.31Å; L312-L366 HydrophobicContact CD2-CD1 4.07Å; L312-L366 HydrophobicContact CD2-CD2 4.24Å; L315-L366 HydrophobicContact CB-CD1 4.15Å; L315-L366 HydrophobicContact CD1-CD1 4.38Å; M316-L366 HydrophobicContact CG-CB 3.67Å; M316-L366 HydrophobicContact CG-CD1 4.15Å; M316-L366 HydrophobicContact SD-CB 3.82Å; F363-L366 HydrophobicContact CB-CD1 3.86Å; F363-L366 HydrophobicContact CB-CG 4.09Å; F363-L366 HydrophobicContact CD1-CD1 4.26Å; F363-L366 HydrophobicContact CG-CD1 4.3Å; F363-L366 WeakPolarHBondContact O-CB 3.23Å; F363-L366 PolarHBondContact O-N 2.87Å; V364-L366 VanDerWaalsContact C-N 3.31Å; V364-L366 PolarHBondContact O-N 2.66Å; L366-L369 HydrophobicContact CD2-CD1 4.19Å
367	F	98.3	Very high	96.4	Very high	54 Å²	54	49.8 Å²	49.8	24%	0.237	25%	0.25	C	C	.	.	H	α-helix	trans	-70.8	-47.4	172.8	-64.4	-97.4	0	0	0	110.5	M316 D319 T320 K361 F363 V364 D365 L369 S370	M316-F367 HydrophobicContact CB-CE1 4.07Å; M316-F367 HydrophobicContact CB-CE2 3.87Å; M316-F367 HydrophobicContact CB-CZ 3.59Å; M316-F367 HydrophobicContact CG-CD2 4.04Å; M316-F367 HydrophobicContact CG-CE1 4.38Å; M316-F367 HydrophobicContact CG-CE2 3.75Å; M316-F367 HydrophobicContact CG-CG 4.49Å; M316-F367 HydrophobicContact CG-CZ 3.96Å; M316-F367 WeakPolarHBondContact O-CZ 3.37Å; M316-F367 HydrophobicContact SD-CD1 4.29Å; M316-F367 HydrophobicContact SD-CD2 4.35Å; M316-F367 HydrophobicContact SD-CE1 4.47Å; M316-F367 HydrophobicContact SD-CG 4.25Å; D319-F367 HydrophobicContact CB-CE2 4.08Å; D319-F367 HydrophobicContact CB-CZ 4.21Å; T320-F367 WeakPolarHBondContact OG1-CZ 3.44Å; K361-F367 HydrophobicContact CD-CD2 3.76Å; K361-F367 HydrophobicContact CD-CE2 3.72Å; K361-F367 HydrophobicContact CD-CG 4.4Å; K361-F367 HydrophobicContact CD-CZ 4.32Å; K361-F367 HydrophobicContact CG-CD2 4.41Å; K361-F367 HydrophobicContact CG-CE2 4.06Å; F363-F367 WeakPolarHBondContact O-CD2 3.26Å; V364-F367 WeakPolarHBondContact O-CB 3.38Å; V364-F367 PolarHBondContact O-N 2.84Å; D365-F367 VanDerWaalsContact C-N 3.25Å; D365-F367 PolarHBondContact O-N 2.83Å; F367-L369 PolarHBondContact O-N 3.05Å; F367-S370 WeakPolarHBondContact O-CB 3.42Å; F367-S370 PolarHBondContact O-N 3.4Å; F367-S370 VanDerWaalsContact O-N 3.14Å; F367-S370 PolarHBondContact O-OG 3.27Å
368	N	97.6	Very high	96.4	Very high	75 Å²	75	48.3 Å²	48.3	40%	0.401	24%	0.237	S	C	.	.	H	α-helix	trans	-68.7	-16.6	-177.3	-71.7	-19.2	0	0	0	113.5	V364 D365 S370 T371	V364-N368 PolarHBondContact O-N 3.41Å; V364-N368 VanDerWaalsContact O-N 3.14Å; D365-N368 CarbonylContact O-C 3.44Å; D365-N368 PolarHBondContact O-N 3.49Å; D365-N368 VanDerWaalsContact O-N 3.1Å; N368-S370 PolarHBondContact O-N 3.02Å; N368-T371 WeakPolarHBondContact O-CB 3.45Å; N368-T371 PolarHBondContact O-N 3.4Å; N368-T371 VanDerWaalsContact O-N 3.07Å; N368-T371 PolarHBondContact O-OG1 3.07Å
369	L	95.7	Very high	96.4	Very high	1 Å²	1	45 Å²	45	1%	0.005	22%	0.22	C	C	.	.	G	3₁₀ helix	trans	-56.1	-28.7	169.4	-74.7	-179.9	0	0	0	112.6	L290 A293 L294 Y297 D365 L366 F367 T371 Y372	L290-L369 HydrophobicContact CD1-CD2 3.5Å; L290-L369 HydrophobicContact CD1-CG 4.2Å; L290-L369 HydrophobicContact CG-CD2 3.81Å; A293-L369 HydrophobicContact CB-CD1 3.63Å; L294-L369 HydrophobicContact CB-CD2 4.37Å; L294-L369 HydrophobicContact CD1-CD2 4.2Å; Y297-L369 HydrophobicContact CE1-CB 4.25Å; Y297-L369 HydrophobicContact CE1-CD1 4.43Å; D365-L369 WeakPolarHBondContact O-CG 3.35Å; D365-L369 PolarHBondContact O-N 3.35Å; L366-L369 HydrophobicContact CD2-CD1 4.19Å; F367-L369 PolarHBondContact O-N 3.05Å; L369-T371 PolarHBondContact O-N 3.33Å; L369-T371 VanDerWaalsContact O-N 3.15Å; L369-Y372 PolarHBondContact O-N 2.92Å
370	S	95.4	Very high	96.4	Very high	68 Å²	68	39.2 Å²	39.2	48%	0.476	20%	0.198	S	C	.	.	G	3₁₀ helix	trans	-59.5	-25.9	177.9	-52.6	0	0	0	0	112.7	F367 N368 Y372 L373	F367-S370 WeakPolarHBondContact O-CB 3.42Å; F367-S370 PolarHBondContact O-N 3.4Å; F367-S370 VanDerWaalsContact O-N 3.14Å; F367-S370 PolarHBondContact O-OG 3.27Å; N368-S370 PolarHBondContact O-N 3.02Å; S370-Y372 PolarHBondContact O-N 3.46Å; S370-L373 WeakPolarHBondContact O-CG 3.25Å; S370-L373 PolarHBondContact O-N 3.5Å
371	T	95.5	Very high	96.1	Very high	77 Å²	77	47.5 Å²	47.5	47%	0.472	23%	0.234	S	C	.	.	G	3₁₀ helix	trans	-61.6	-27.6	174.5	-54.5	0	0	0	0	112.5	V264 N368 L369	V264-T371 HydrophobicContact CG1-CG2 3.45Å; V264-T371 VanDerWaalsContact CG1-CG2 3.45Å; N368-T371 WeakPolarHBondContact O-CB 3.45Å; N368-T371 PolarHBondContact O-N 3.4Å; N368-T371 VanDerWaalsContact O-N 3.07Å; N368-T371 PolarHBondContact O-OG1 3.07Å; L369-T371 PolarHBondContact O-N 3.33Å; L369-T371 VanDerWaalsContact O-N 3.15Å
372	Y	95.8	Very high	95.5	Very high	25 Å²	25	46.9 Å²	46.9	10%	0.098	23%	0.232	C	C	.	.	G	3₁₀ helix	trans	-104.6	14.9	-173.4	-51.9	-67	0	0	0	113.4	V264 L268 R283 L369 S370	V264-Y372 HydrophobicContact CG1-CE1 4.18Å; V264-Y372 WeakPolarHBondContact O-CE1 3.23Å; L268-Y372 HydrophobicContact CB-CD1 3.9Å; L268-Y372 HydrophobicContact CB-CE1 4.01Å; L268-Y372 HydrophobicContact CD1-CD1 4Å; L268-Y372 HydrophobicContact CD1-CD2 3.84Å; L268-Y372 HydrophobicContact CD1-CE1 4.11Å; L268-Y372 HydrophobicContact CD1-CE2 3.97Å; L268-Y372 HydrophobicContact CD1-CG 3.86Å; L268-Y372 HydrophobicContact CD2-CD1 4.19Å; L268-Y372 HydrophobicContact CD2-CG 4.08Å; L268-Y372 HydrophobicContact CG-CD1 4.24Å; L268-Y372 HydrophobicContact CG-CG 4.37Å; R283-Y372 PolarHBondContact NH2-OH 3.2Å; L369-Y372 PolarHBondContact O-N 2.92Å; S370-Y372 PolarHBondContact O-N 3.46Å
373	L	94.9	Very high	94.7	Very high	87 Å²	87	50 Å²	50	46%	0.455	25%	0.249	S	C	.	.			trans	-70.5	135.8	175.4	-63.8	177.5	0	0	0	110.3	F298 S370	F298-L373 HydrophobicContact CE1-CD2 3.8Å; F298-L373 HydrophobicContact CZ-CD2 4.44Å; S370-L373 WeakPolarHBondContact O-CG 3.25Å; S370-L373 PolarHBondContact O-N 3.5Å
374	V	95.4	Very high	93.5	Very high	17 Å²	17	55.3 Å²	55.3	10%	0.103	28%	0.283	C	S	.	.			trans	-122.9	163.3	-179.6	-62.5	0	0	0	0	110.7	F227 I231 L265 F298 W378 I379	F227-V374 HydrophobicContact CE2-CG2 3.66Å; F227-V374 HydrophobicContact CZ-CG1 4.38Å; F227-V374 HydrophobicContact CZ-CG2 4.08Å; I231-V374 HydrophobicContact CD1-CG1 4.05Å; I231-V374 HydrophobicContact CG1-CG1 4.12Å; L265-V374 HydrophobicContact CD1-CG1 4.21Å; L265-V374 HydrophobicContact CD2-CG1 3.97Å; F298-V374 HydrophobicContact CE1-CG2 4.49Å; F298-V374 HydrophobicContact CZ-CG2 4.21Å; V374-W378 HydrophobicContact CB-CB 4.21Å; V374-W378 HydrophobicContact CB-CD2 4.4Å; V374-W378 HydrophobicContact CB-CE3 3.88Å; V374-W378 HydrophobicContact CG1-CE3 3.98Å; V374-W378 HydrophobicContact CG1-CZ3 4.49Å; V374-W378 HydrophobicContact CG2-CB 3.86Å; V374-I379 HydrophobicContact CG2-CG1 4.29Å
375	P	95.4	Very high	92.2	Very high	51 Å²	51	61.2 Å²	61.2	33%	0.331	31%	0.314	S	S	.	.			trans	-52.7	143.9	172	-27.1	36.1	0	0	0	112.3	H377 W378	P375-H377 WeakPolarHBondContact CB-CE1 3.47Å; P375-H377 PolarHBondContact O-N 3.1Å; P375-W378 HydrophobicContact CB-CG 4.39Å; P375-W378 HydrophobicContact CG-CD2 4.31Å; P375-W378 HydrophobicContact CG-CZ2 4.46Å; P375-W378 WeakPolarHBondContact O-CB 3.4Å; P375-W378 PolarHBondContact O-N 3.43Å
376	R	92.6	Very high	90.9	Very high	149 Å²	149	62.5 Å²	62.5	56%	0.562	32%	0.32	S	S	*	.	G	3₁₀ helix	trans	-55	-32.3	-175.1	-69.4	-65.2	-177.6	160.1	5.4	114.4	R300 W378 I379	R300-R376 VanDerWaalsContact NH1-NH1 3.18Å; R376-W378 PolarHBondContact O-N 2.95Å; R376-I379 WeakPolarHBondContact O-CB 3.38Å; R376-I379 PolarHBondContact O-N 3.21Å
377	H	93.6	Very high	89.5	Confident	128 Å²	128	65.6 Å²	65.6	59%	0.593	33%	0.334	S	S	*	.	G	3₁₀ helix	trans	-74.8	-12.6	-179.4	62.4	-81.8	0	0	0	113.4	P375	P375-H377 WeakPolarHBondContact CB-CE1 3.47Å; P375-H377 PolarHBondContact O-N 3.1Å
378	W	95.9	Very high	88.2	Confident	12 Å²	12	70.6 Å²	70.6	5%	0.045	36%	0.356	C	S	.	.	G	3₁₀ helix	trans	-86.4	-17.1	173	-61.7	10.6	0	0	0	111.9	N230 I231 G234 L235 E238 L265 V374 P375 R376	N230-W378 WeakPolarHBondContact CB-O 3.43Å; N230-W378 PolarHBondContact ND2-O 2.86Å; I231-W378 HydrophobicContact CG1-CE3 4.3Å; G234-W378 VanDerWaalsContact CA-CE2 3.47Å; G234-W378 VanDerWaalsContact CA-CZ2 3.41Å; G234-W378 VanDerWaalsContact O-CZ2 3.26Å; G234-W378 WeakPolarHBondContact O-CZ2 3.38Å; L235-W378 HydrophobicContact CD2-CH2 4.25Å; L235-W378 HydrophobicContact CD2-CZ3 4.34Å; L235-W378 HydrophobicContact CG-CH2 4.29Å; L235-W378 HydrophobicContact CG-CZ3 4.19Å; E238-W378 HydrophobicContact CG-CH2 4.06Å; E238-W378 HydrophobicContact CG-CZ2 3.71Å; L265-W378 HydrophobicContact CD1-CZ3 4.35Å; V374-W378 HydrophobicContact CB-CB 4.21Å; V374-W378 HydrophobicContact CB-CD2 4.4Å; V374-W378 HydrophobicContact CB-CE3 3.88Å; V374-W378 HydrophobicContact CG1-CE3 3.98Å; V374-W378 HydrophobicContact CG1-CZ3 4.49Å; V374-W378 HydrophobicContact CG2-CB 3.86Å; P375-W378 HydrophobicContact CB-CG 4.39Å; P375-W378 HydrophobicContact CG-CD2 4.31Å; P375-W378 HydrophobicContact CG-CZ2 4.46Å; P375-W378 WeakPolarHBondContact O-CB 3.4Å; P375-W378 PolarHBondContact O-N 3.43Å; R376-W378 PolarHBondContact O-N 2.95Å
379	I	96.2	Very high	87.1	Confident	17 Å²	17	70.9 Å²	70.9	9%	0.087	35%	0.354	C	S	.	.	S	Bend	trans	-67	130	176.7	-58.5	173.6	0	0	0	108.3	F298 Y299 V374 R376 K381	F298-I379 HydrophobicContact CB-CD1 4.11Å; F298-I379 HydrophobicContact CB-CG2 3.91Å; F298-I379 HydrophobicContact CD1-CD1 3.49Å; F298-I379 VanDerWaalsContact CD1-CD1 3.49Å; F298-I379 HydrophobicContact CD1-CG1 3.94Å; F298-I379 HydrophobicContact CE1-CD1 4.12Å; F298-I379 HydrophobicContact CE1-CG1 4.29Å; F298-I379 HydrophobicContact CG-CD1 3.94Å; F298-I379 HydrophobicContact CG-CG1 4.14Å; F298-I379 HydrophobicContact CG-CG2 4.25Å; Y299-I379 HydrophobicContact CE1-CG2 3.79Å; Y299-I379 HydrophobicContact CE2-CG2 4.43Å; V374-I379 HydrophobicContact CG2-CG1 4.29Å; R376-I379 WeakPolarHBondContact O-CB 3.38Å; R376-I379 PolarHBondContact O-N 3.21Å; I379-K381 PolarHBondContact O-N 3.17Å
380	P	95.3	Very high	85.9	Confident	4 Å²	4	70.9 Å²	70.9	3%	0.026	35%	0.354	C	S	.	.	P	Polyproline II helix	trans	-53.4	131.2	179.4	-27.7	34.5	0	0	0	111.9	F221 F223 K226 F227 Y299 M382	F221-P380 HydrophobicContact CZ-CB 4.04Å; F223-P380 HydrophobicContact CD2-CG 4.39Å; K226-P380 HydrophobicContact CB-CB 3.87Å; K226-P380 HydrophobicContact CB-CG 3.79Å; K226-P380 HydrophobicContact CD-CB 4.41Å; F227-P380 HydrophobicContact CB-CG 4.05Å; F227-P380 HydrophobicContact CD2-CG 4.43Å; Y299-P380 WeakPolarHBondContact CE1-O 3.44Å; Y299-P380 WeakPolarHBondContact OH-CB 3.45Å; Y299-P380 PolarHBondContact OH-O 3.03Å; P380-M382 PolarHBondContact O-N 3.11Å
381	K	90.7	Very high	84.4	Confident	183 Å²	183	75 Å²	75	80%	0.796	36%	0.36	S	S	*	.	P	Polyproline II helix	trans	-72.9	133.7	178.3	-65.6	-174.3	-179.8	179.8	0	109.8	I379	I379-K381 PolarHBondContact O-N 3.17Å
382	M	85	Confident	82.5	Confident	23 Å²	23	75.4 Å²	75.4	11%	0.113	36%	0.362	C	S	.	.	P	Polyproline II helix	trans	-69.7	133.5	170	-71.4	-73.1	-174.9	0	0	109.4	F221 M295 Y299 P380 I386 H387 L390	F221-M382 HydrophobicContact CD2-SD 4.31Å; F221-M382 HydrophobicContact CE1-CE 4.11Å; F221-M382 HydrophobicContact CE1-SD 4.18Å; F221-M382 HydrophobicContact CE2-SD 3.82Å; F221-M382 HydrophobicContact CZ-CE 4.17Å; F221-M382 HydrophobicContact CZ-SD 3.74Å; M295-M382 HydrophobicContact CE-CE 3.43Å; M295-M382 VanDerWaalsContact CE-CE 3.43Å; Y299-M382 HydrophobicContact CD1-CE 3.27Å; Y299-M382 HydrophobicContact CD1-CG 3.95Å; Y299-M382 HydrophobicContact CD1-SD 4.46Å; Y299-M382 HydrophobicContact CD2-CE 3.65Å; Y299-M382 HydrophobicContact CE1-CE 3.47Å; Y299-M382 VanDerWaalsContact CE1-CE 3.47Å; Y299-M382 HydrophobicContact CE1-CG 3.79Å; Y299-M382 HydrophobicContact CE1-SD 4.32Å; Y299-M382 HydrophobicContact CE2-CE 3.86Å; Y299-M382 HydrophobicContact CG-CE 3.36Å; P380-M382 PolarHBondContact O-N 3.11Å; M382-I386 HydrophobicContact CE-CG2 4.39Å; M382-I386 HydrophobicContact SD-CB 4.18Å; M382-I386 HydrophobicContact SD-CG2 3.35Å; M382-I386 WeakPolarHBondContact SD-CG2 3.26Å; M382-H387 WeakPolarHBondContact CB-CD2 3.42Å; M382-H387 VanDerWaalsContact CB-NE2 3.26Å; M382-H387 WeakPolarHBondContact CB-NE2 3.49Å; M382-L390 HydrophobicContact CE-CD1 3.32Å; M382-L390 HydrophobicContact SD-CD1 3.86Å
383	N	80.8	Confident	80.6	Confident	69 Å²	69	77.2 Å²	77.2	37%	0.369	38%	0.382	S	S	.	.	P	Polyproline II helix	trans	-81.8	161.9	169.1	74.9	3.2	0	0	0	109.4	I385 I386 H387	N383-I385 PolarHBondContact O-N 3.3Å; N383-I385 VanDerWaalsContact O-N 3.12Å; N383-I385 PolarHBondContact OD1-N 3.28Å; N383-I386 PolarHBondContact O-N 3.37Å; N383-I386 VanDerWaalsContact OD1-CB 3.27Å; N383-I386 WeakPolarHBondContact OD1-CB 3.24Å; N383-I386 WeakPolarHBondContact OD1-CG1 3.32Å; N383-I386 PolarHBondContact OD1-N 3.42Å; N383-H387 PolarHBondContact O-N 3.26Å
384	P	74	Confident	78.7	Confident	111 Å²	111	77.6 Å²	77.6	72%	0.721	38%	0.382	S	S	*	.	H	α-helix	trans	-58.4	-28	-178.7	-27.3	35.8	0	0	0	114.6	K388	P384-K388 PolarHBondContact O-N 2.97Å; P384-K388 VanDerWaalsContact O-N 3.12Å
385	I	70.7	Confident	76.3	Confident	132 Å²	132	83.6 Å²	83.6	68%	0.677	40%	0.404	S	S	*	.	H	α-helix	trans	-71.8	-45.5	-179.8	-62.8	171.6	0	0	0	110.8	N383 K388 F389	N383-I385 PolarHBondContact O-N 3.3Å; N383-I385 VanDerWaalsContact O-N 3.12Å; N383-I385 PolarHBondContact OD1-N 3.28Å; I385-K388 PolarHBondContact O-N 2.76Å; I385-F389 PolarHBondContact O-N 3.45Å; I385-F389 VanDerWaalsContact O-N 3.13Å
386	I	71.9	Confident	73.9	Confident	29 Å²	29	84.6 Å²	84.6	15%	0.149	41%	0.411	C	S	.	.	H	α-helix	trans	-72.2	-36.3	178	-62.6	-65.2	0	0	0	110.6	F221 M382 N383 K388 F389 L390	F221-I386 HydrophobicContact CB-CD1 4.05Å; F221-I386 HydrophobicContact CB-CG1 4.22Å; F221-I386 HydrophobicContact CB-CG2 4.37Å; F221-I386 HydrophobicContact CD2-CB 4.38Å; F221-I386 HydrophobicContact CD2-CG1 4Å; F221-I386 HydrophobicContact CD2-CG2 4.1Å; F221-I386 HydrophobicContact CG-CG1 4.47Å; F221-I386 HydrophobicContact CG-CG2 4.25Å; M382-I386 HydrophobicContact CE-CG2 4.39Å; M382-I386 HydrophobicContact SD-CB 4.18Å; M382-I386 HydrophobicContact SD-CG2 3.35Å; M382-I386 WeakPolarHBondContact SD-CG2 3.26Å; N383-I386 PolarHBondContact O-N 3.37Å; N383-I386 VanDerWaalsContact OD1-CB 3.27Å; N383-I386 WeakPolarHBondContact OD1-CB 3.24Å; N383-I386 WeakPolarHBondContact OD1-CG1 3.32Å; N383-I386 PolarHBondContact OD1-N 3.42Å; I386-K388 VanDerWaalsContact C-N 3.29Å; I386-K388 PolarHBondContact O-N 3.04Å; I386-F389 PolarHBondContact O-N 2.98Å; I386-L390 HydrophobicContact CG2-CD1 4.09Å; I386-L390 HydrophobicContact CG2-CG 4.42Å; I386-L390 WeakPolarHBondContact O-CG 3.45Å; I386-L390 PolarHBondContact O-N 3.34Å
387	H	69.4	Low	71.4	Confident	66 Å²	66	80.3 Å²	80.3	31%	0.306	40%	0.399	S	S	.	.	H	α-helix	trans	-54.2	-48	168.7	-91.2	-63.8	0	0	0	110.8	E302 M382 N383 F389 L390 Y391	E302-H387 IonicContact OE1-CE1 3.22Å; E302-H387 PolarHBondContact OE1-CE1 3.38Å; E302-H387 IonicContact OE1-ND1 3.15Å; E302-H387 PolarHBondContact OE1-ND1 2.9Å; E302-H387 IonicContact OE2-CE1 3.93Å; E302-H387 IonicContact OE2-ND1 3.77Å; E302-H387 PolarHBondContact OE2-ND1 2.95Å; M382-H387 WeakPolarHBondContact CB-CD2 3.42Å; M382-H387 VanDerWaalsContact CB-NE2 3.26Å; M382-H387 WeakPolarHBondContact CB-NE2 3.49Å; N383-H387 PolarHBondContact O-N 3.26Å; H387-F389 VanDerWaalsContact C-N 3.33Å; H387-F389 PolarHBondContact O-N 3.38Å; H387-L390 PolarHBondContact O-N 2.96Å; H387-L390 VanDerWaalsContact O-N 3.11Å; H387-Y391 WeakPolarHBondContact O-CD2 3.25Å; H387-Y391 PolarHBondContact O-N 2.92Å
388	K	70.8	Confident	69.1	Low	159 Å²	159	76.9 Å²	76.9	69%	0.691	39%	0.39	S	S	*	.	H	α-helix	trans	-61	-40	178.4	-166.4	176.3	-179.6	-178.6	0	112.6	P384 I385 I386 L390 Y391 T392	P384-K388 PolarHBondContact O-N 2.97Å; P384-K388 VanDerWaalsContact O-N 3.12Å; I385-K388 PolarHBondContact O-N 2.76Å; I386-K388 VanDerWaalsContact C-N 3.29Å; I386-K388 PolarHBondContact O-N 3.04Å; K388-L390 VanDerWaalsContact C-N 3.3Å; K388-L390 PolarHBondContact O-N 3.31Å; K388-Y391 WeakPolarHBondContact O-CB 3.31Å; K388-Y391 PolarHBondContact O-N 3.3Å; K388-Y391 VanDerWaalsContact O-N 3.16Å; K388-T392 PolarHBondContact O-N 2.95Å; K388-T392 PolarHBondContact O-OG1 3.2Å; K388-T392 VanDerWaalsContact O-OG1 3.1Å
389	F	74.1	Confident	66.6	Low	81 Å²	81	80 Å²	80	36%	0.355	41%	0.414	S	S	.	.	H	α-helix	trans	-64.4	-33	175.8	179.9	-115.7	0	0	0	113.1	P214 R304 I385 I386 H387 Y391 E394	P214-F389 HydrophobicContact CB-CD1 4.4Å; P214-F389 HydrophobicContact CB-CE1 3.52Å; P214-F389 HydrophobicContact CB-CZ 4.27Å; R304-F389 VanDerWaalsContact CD-O 3.28Å; R304-F389 WeakPolarHBondContact CD-O 3.27Å; R304-F389 VanDerWaalsContact NH1-CZ 3.26Å; R304-F389 PolarHBondContact NH1-O 2.99Å; I385-F389 PolarHBondContact O-N 3.45Å; I385-F389 VanDerWaalsContact O-N 3.13Å; I386-F389 PolarHBondContact O-N 2.98Å; H387-F389 VanDerWaalsContact C-N 3.33Å; H387-F389 PolarHBondContact O-N 3.38Å; F389-Y391 PolarHBondContact O-N 3.4Å; F389-E394 WeakPolarHBondContact CZ-OE1 3.33Å
390	L	71.1	Confident	63.9	Low	1 Å²	1	88.7 Å²	88.7	1%	0.005	45%	0.447	C	S	.	.	T	Hydrogen-bonded Turn	trans	-81.2	-0.7	176	-66.6	176	0	0	0	114.4	P214 E302 R304 F305 M382 I386 H387 K388	P214-L390 HydrophobicContact CB-CD2 4.41Å; P214-L390 HydrophobicContact CG-CD2 4.11Å; E302-L390 HydrophobicContact CB-CB 4.25Å; E302-L390 HydrophobicContact CB-CD1 4.48Å; E302-L390 HydrophobicContact CG-CD1 4.21Å; R304-L390 WeakPolarHBondContact CB-O 3.36Å; R304-L390 VanDerWaalsContact CG-O 3.23Å; R304-L390 WeakPolarHBondContact CG-O 3.26Å; R304-L390 PolarHBondContact N-O 2.84Å; R304-L390 VanDerWaalsContact N-O 3.14Å; F305-L390 HydrophobicContact CD2-CD1 4.41Å; F305-L390 HydrophobicContact CD2-CD2 4.33Å; F305-L390 HydrophobicContact CE1-CD2 4.35Å; F305-L390 HydrophobicContact CE2-CD1 3.77Å; F305-L390 HydrophobicContact CE2-CD2 3.58Å; F305-L390 HydrophobicContact CE2-CG 4.32Å; F305-L390 HydrophobicContact CZ-CD2 3.6Å; M382-L390 HydrophobicContact CE-CD1 3.32Å; M382-L390 HydrophobicContact SD-CD1 3.86Å; I386-L390 HydrophobicContact CG2-CD1 4.09Å; I386-L390 HydrophobicContact CG2-CG 4.42Å; I386-L390 WeakPolarHBondContact O-CG 3.45Å; I386-L390 PolarHBondContact O-N 3.34Å; H387-L390 PolarHBondContact O-N 2.96Å; H387-L390 VanDerWaalsContact O-N 3.11Å; K388-L390 VanDerWaalsContact C-N 3.3Å; K388-L390 PolarHBondContact O-N 3.31Å
391	Y	62.9	Low	61.2	Low	154 Å²	154	97.8 Å²	97.8	60%	0.604	49%	0.486	S	S	*	.	T	Hydrogen-bonded Turn	trans	-101.2	-31.5	172.5	-91	-111.1	0	0	0	113.2	P303 H387 K388 F389	P303-Y391 HydrophobicContact CG-CD1 3.85Å; P303-Y391 HydrophobicContact CG-CD2 3.95Å; P303-Y391 HydrophobicContact CG-CE1 3.77Å; P303-Y391 HydrophobicContact CG-CE2 3.9Å; P303-Y391 HydrophobicContact CG-CG 3.96Å; H387-Y391 WeakPolarHBondContact O-CD2 3.25Å; H387-Y391 PolarHBondContact O-N 2.92Å; K388-Y391 WeakPolarHBondContact O-CB 3.31Å; K388-Y391 PolarHBondContact O-N 3.3Å; K388-Y391 VanDerWaalsContact O-N 3.16Å; F389-Y391 PolarHBondContact O-N 3.4Å
392	T	56.8	Low	58.7	Low	85 Å²	85	93.5 Å²	93.5	52%	0.521	48%	0.479	S	S	.	.	S	Bend	trans	-90.5	110.6	178.9	30.6	0	0	0	0	111.3	R304 K388	R304-T392 WeakPolarHBondContact CD-O 3.45Å; K388-T392 PolarHBondContact O-N 2.95Å; K388-T392 PolarHBondContact O-OG1 3.2Å; K388-T392 VanDerWaalsContact O-OG1 3.1Å
393	A	55.9	Low	56.6	Low	63 Å²	63	97.4 Å²	97.4	52%	0.521	51%	0.509	S	S	.	.			trans	-62.7	139.2	171.6	0	0	0	0	0	111.1	E106 Y395	E106-A393 HydrophobicContact CB-CB 4.37Å; E106-A393 WeakPolarHBondContact OE2-CA 3.43Å; E106-A393 WeakPolarHBondContact OE2-CB 3.47Å; A393-Y395 PolarHBondContact O-N 3.1Å
394	E	54.4	Low	54.5	Low	96 Å²	96	101.8 Å²	101.8	45%	0.449	53%	0.532	S	S	.	.			trans	-75.4	120.6	174	-81.3	171.8	-147	0	0	110.2	R304 F389	R304-E394 IonicContact CZ-OE1 3.41Å; R304-E394 IonicContact NH1-OE1 3.22Å; R304-E394 IonicContact NH2-OE1 3.62Å; R304-E394 PolarHBondContact NH2-OE1 2.89Å; F389-E394 WeakPolarHBondContact CZ-OE1 3.33Å
395	Y	45.2	Very low	52.8	Low	143 Å²	143	105.8 Å²	105.8	56%	0.561	54%	0.542	S	S	*	.			trans	-90.9	104.8	173.6	-177.2	-96.8	0	0	0	109	R107 A393 D397	R107-Y395 VanDerWaalsContact CZ-CE2 3.46Å; R107-Y395 VanDerWaalsContact NH1-CE2 3.26Å; A393-Y395 PolarHBondContact O-N 3.1Å; Y395-D397 HydrophobicContact CD1-CB 4.19Å; Y395-D397 HydrophobicContact CE1-CB 3.41Å; Y395-D397 VanDerWaalsContact CE1-CB 3.41Å; Y395-D397 VanDerWaalsContact CE1-OD2 3.29Å; Y395-D397 WeakPolarHBondContact CE1-OD2 3.37Å; Y395-D397 PolarHBondContact OH-OD1 3.2Å; Y395-D397 PolarHBondContact OH-OD2 3.11Å
396	C	45.4	Very low	51.4	Low	72 Å²	72	104.5 Å²	104.5	49%	0.486	54%	0.544	S	S	.	.			trans	-98.4	108.1	162.3	-96.1	0	0	0	0	107.7	S398	C396-S398 PolarHBondContact O-N 3.2Å
397	D	38.6	Very low	49.7	Very low	58 Å²	58	114.9 Å²	114.9	31%	0.31	60%	0.6	S	S	.	*			trans	-70.8	99.4	175.5	-149.1	-28.6	0	0	0	109.9	Y395 S399	Y395-D397 HydrophobicContact CD1-CB 4.19Å; Y395-D397 HydrophobicContact CE1-CB 3.41Å; Y395-D397 VanDerWaalsContact CE1-CB 3.41Å; Y395-D397 VanDerWaalsContact CE1-OD2 3.29Å; Y395-D397 WeakPolarHBondContact CE1-OD2 3.37Å; Y395-D397 PolarHBondContact OH-OD1 3.2Å; Y395-D397 PolarHBondContact OH-OD2 3.11Å; D397-S399 VanDerWaalsContact CG-OG 3.23Å; D397-S399 PolarHBondContact O-N 3.02Å; D397-S399 VanDerWaalsContact OD1-CB 3.31Å; D397-S399 WeakPolarHBondContact OD1-CB 3.5Å; D397-S399 PolarHBondContact OD1-N 3.29Å; D397-S399 PolarHBondContact OD1-OG 2.97Å
398	S	45.4	Very low	48.7	Very low	57 Å²	57	117.4 Å²	117.4	40%	0.399	62%	0.615	S	S	.	*	G	3₁₀ helix	trans	-75.3	-4.7	175.8	59.9	0	0	0	0	113.2	C396 Y400 F401	C396-S398 PolarHBondContact O-N 3.2Å; S398-Y400 PolarHBondContact O-N 3.25Å; S398-F401 PolarHBondContact O-N 3.32Å
399	S	43.8	Very low	47.6	Very low	78 Å²	78	115.2 Å²	115.2	55%	0.545	61%	0.611	S	S	.	*	G	3₁₀ helix	trans	-69.6	-12.3	178.5	67	0	0	0	0	114.2	D397	D397-S399 VanDerWaalsContact CG-OG 3.23Å; D397-S399 PolarHBondContact O-N 3.02Å; D397-S399 VanDerWaalsContact OD1-CB 3.31Å; D397-S399 WeakPolarHBondContact OD1-CB 3.5Å; D397-S399 PolarHBondContact OD1-N 3.29Å; D397-S399 PolarHBondContact OD1-OG 2.97Å
400	Y	40.1	Very low	46.1	Very low	199 Å²	199	117.1 Å²	117.1	78%	0.78	63%	0.625	S	S	*	*	G	3₁₀ helix	trans	-91.6	-2.9	177.9	-92.3	-87.9	0	0	0	115	S398	S398-Y400 PolarHBondContact O-N 3.25Å
401	F	39.1	Very low	44.6	Very low	194 Å²	194	123.9 Å²	123.9	85%	0.851	66%	0.661	S	S	*	*			trans	-101	29.9	175.8	-69.5	-79	0	0	0	112.7	S398	S398-F401 PolarHBondContact O-N 3.32Å
402	S	37.3	Very low	43.5	Very low	93 Å²	93	122 Å²	122	65%	0.65	67%	0.665	S	S	*	*	S	Bend	trans	-81.4	115.7	163.9	174.1	0	0	0	0	108.3	D404	S402-D404 PolarHBondContact O-N 2.73Å
403	S	40.3	Very low	42.6	Very low	105 Å²	105	124.5 Å²	124.5	73%	0.734	68%	0.675	S	S	*	*			trans	-29.5	109.2	171.7	51.7	0	0	0	0	115.7
404	D	38.1	Very low	41.7	Very low	162 Å²	162	128.9 Å²	128.9	87%	0.866	69%	0.686	S	S	*	*			trans	-101.7	75	150.6	-85.4	-19.1	0	0	0	107.7	S402	S402-D404 PolarHBondContact O-N 2.73Å
405	E	38.1	Very low	40.7	Very low	195 Å²	195	131.4 Å²	131.4	91%	0.911	70%	0.704	S	S	*	*			trans	-143.3	81.9	152.4	-80.8	-159.4	168.7	0	0	107.8
406	S	40.8	Very low	40.3	Very low	105 Å²	105	130.4 Å²	130.4	73%	0.734	72%	0.716	S	S	*	*			trans	-133.5	103.1	154.1	58.6	0	0	0	0	107.2
407	D	36.7	Very low	39.8	Very low	247 Å²	247	135.7 Å²	135.7	100%	1.321	74%	0.737	S	S	*	*			trans	-156.1	0	143.5	-93.5	-20.7	0	0	0	109.1

Retrieved 407 of 407 residues in 125.1 ms (Link to these results)

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