A0A068BCA9_HUMAN Loading...

Truncated breast and ovarian cancer susceptibility protein 2

AlphaFold DB , UniProt , Accession A0A068BCA9, Species HUMAN (Homo sapiens, Human), Gene BRCA2, Length 56 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1K55.6Low60.7Low258 Ų258169.1 Ų169.1100%1.12282%0.817SS**  0104.20-59.6176.7138.8-177.50105.9
2W49.8Very low60.8Low257 Ų257162.8 Ų162.897%0.97380%0.8SS**PPolyproline II helixtrans-85.1139.5-175.3-67.276.9000109.3
3L60.9Low60.7Low176 Ų176164.2 Ų164.292%0.92180%0.803SS**PPolyproline II helixtrans-60.5138.3-176.3-77.3158.6000110.4E5L3-E5 PolarHBondContact O-N 3.49Å
4R66.3Low60.8Low233 Ų233168.1 Ų168.188%0.87981%0.805SS**PPolyproline II helixtrans-65.6125.5-177.8-175.1-170.9-60.7-97.92.2109.7G6R4-G6 PolarHBondContact O-N 3.04Å; R4-G6 VanDerWaalsContact O-N 3.08Å
5E64.8Low60.8Low194 Ų194166.4 Ų166.491%0.90780%0.8SS**  trans-66.9103.5166.6-69.3178.1169.500108.3L3L3-E5 PolarHBondContact O-N 3.49Å
6G60.5Low60.8Low62 Ų62161.9 Ų161.964%0.63978%0.782SS**  trans-86.9126.816900000108.5R4 F8R4-G6 PolarHBondContact O-N 3.04Å; R4-G6 VanDerWaalsContact O-N 3.08Å; G6-F8 PolarHBondContact O-N 3.43Å
7I58.2Low60.6Low139 Ų139158.5 Ų158.571%0.71377%0.773SS**  trans-54.2124.5177.9-47.3-178.1000108.8D9I7-D9 VanDerWaalsContact CG2-CG 3.41Å; I7-D9 WeakPolarHBondContact CG2-OD1 3.37Å; I7-D9 WeakPolarHBondContact CG2-OD2 3.06Å; I7-D9 PolarHBondContact O-N 3.04Å
8F61Low60.4Low168 Ų168153.3 Ų153.374%0.73776%0.76SS**  trans-80.970.3-178.1-159-92.2000109.1G6 G10G6-F8 PolarHBondContact O-N 3.43Å; F8-G10 WeakPolarHBondContact CE1-O 3.32Å; F8-G10 PolarHBondContact O-N 3.07Å; F8-G10 VanDerWaalsContact CE1-O 3.22Å; F8-G10 WeakPolarHBondContact CD1-O 3.12Å; F8-G10 VanDerWaalsContact C-N 3.25Å
9D61.6Low60.2Low139 Ų139152.6 Ų152.674%0.74376%0.759SS**  trans-89.520.8-176.2-64-31.7000113.5I7I7-D9 VanDerWaalsContact CG2-CG 3.41Å; I7-D9 WeakPolarHBondContact CG2-OD1 3.37Å; I7-D9 WeakPolarHBondContact CG2-OD2 3.06Å; I7-D9 PolarHBondContact O-N 3.04Å
10G63.7Low60.1Low46 Ų46154.2 Ų154.247%0.47476%0.757SS.*SBendtrans-115.9121.1167.800000107.6F8F8-G10 WeakPolarHBondContact CE1-O 3.32Å; F8-G10 PolarHBondContact O-N 3.07Å; F8-G10 VanDerWaalsContact CE1-O 3.22Å; F8-G10 WeakPolarHBondContact CD1-O 3.12Å; F8-G10 VanDerWaalsContact C-N 3.25Å
11Q64.8Low60Low188 Ų188152.4 Ų152.488%0.87976%0.755SS**  trans-36.4136.9168.9-63.3174.3-95.600110.1E13Q11-E13 PolarHBondContact O-N 2.82Å
12P62.7Low60.1Low94 Ų94142.7 Ų142.761%0.6173%0.728SS**  trans-60117.3171.625.4-30.1000106R14P12-R14 PolarHBondContact O-N 2.89Å
13E59.8Low60.6Low180 Ų180137.4 Ų137.484%0.84172%0.719SS**  trans-41.2120.5159.3-112.6179.8165.200105.2Q11 I15Q11-E13 PolarHBondContact O-N 2.82Å; E13-I15 VanDerWaalsContact O-CG1 3.3Å; E13-I15 WeakPolarHBondContact O-CG1 3.4Å; E13-I15 PolarHBondContact O-N 3.04Å
14R61Low60.4Low220 Ų220139 Ų13983%0.8371%0.714SS**  trans-55.595.5-177.5-86.8171.457.7-153.1-3106.8P12 N16P12-R14 PolarHBondContact O-N 2.89Å; R14-N16 VanDerWaalsContact C-N 3.27Å; R14-N16 PolarHBondContact O-N 2.79Å
15I61.1Low60.2Low142 Ų142135.4 Ų135.473%0.72871%0.712SS**  trans-64.8101.2174.1-40.4176.6000102.9E13 T17E13-I15 VanDerWaalsContact O-CG1 3.3Å; E13-I15 WeakPolarHBondContact O-CG1 3.4Å; E13-I15 PolarHBondContact O-N 3.04Å; I15-T17 PolarHBondContact O-N 3.33Å
16N62Low60Low95 Ų95136.5 Ų136.551%0.50871%0.709SS.*  trans-68.2104.5-179.4-138.70.6000104.1R14 A18 D19R14-N16 VanDerWaalsContact C-N 3.27Å; R14-N16 PolarHBondContact O-N 2.79Å; N16-A18 PolarHBondContact O-N 2.87Å; N16-D19 PolarHBondContact O-N 2.74Å
17T56.7Low59.8Low103 Ų103141.9 Ų141.963%0.63272%0.718SS**G310 helixtrans-54.5-17.6-173.3-38.90000112.5I15 D19 Y20 V21I15-T17 PolarHBondContact O-N 3.33Å; T17-D19 VanDerWaalsContact C-N 3.3Å; T17-D19 PolarHBondContact O-N 2.81Å; T17-Y20 PolarHBondContact O-N 3.05Å; T17-V21 WeakPolarHBondContact O-CG2 3.45Å; T17-V21 PolarHBondContact O-N 2.87Å
18A56.3Low59.9Low65 Ų65141 Ų14154%0.53771%0.714SS.*G310 helixtrans-56.6-35.9170.100000113.9N16 Y20 V21 G22N16-A18 PolarHBondContact O-N 2.87Å; A18-Y20 VanDerWaalsContact C-N 3.28Å; A18-Y20 PolarHBondContact O-N 3.1Å; A18-V21 PolarHBondContact O-N 2.63Å; A18-G22 PolarHBondContact O-N 2.78Å
19D56.6Low60Low141 Ų141138.5 Ų138.575%0.75471%0.709SS**G310 helixtrans-76.1-17.2179-65.4-27.2000112.4N16 T17N16-D19 PolarHBondContact O-N 2.74Å; T17-D19 VanDerWaalsContact C-N 3.3Å; T17-D19 PolarHBondContact O-N 2.81Å
20Y58.3Low60Low184 Ų184135.8 Ų135.872%0.72270%0.701SS**THydrogen-bonded Turntrans-84.7-21.1173.3-155.9-94.1000112.6T17 A18T17-Y20 PolarHBondContact O-N 3.05Å; A18-Y20 VanDerWaalsContact C-N 3.28Å; A18-Y20 PolarHBondContact O-N 3.1Å
21V58.6Low60.1Low116 Ų116140.2 Ų140.270%0.70371%0.714SS**SBendtrans-96.80.8-179.9-178.30000111.5T17 A18T17-V21 WeakPolarHBondContact O-CG2 3.45Å; T17-V21 PolarHBondContact O-N 2.87Å; A18-V21 PolarHBondContact O-N 2.63Å
22G58Low59.9Low55 Ų55135.7 Ų135.757%0.56770%0.703SS**SBendtrans-107.733.2-169.700000116.2A18A18-G22 PolarHBondContact O-N 2.78Å
23N59.8Low59.8Low146 Ų146137.3 Ų137.378%0.78171%0.711SS**SBendtrans-16143.6162.2-140.723.3000115.8
24Y57.5Low59.9Low209 Ų209136.3 Ų136.382%0.8271%0.71SS**  trans-101.18.7167.7-84.5-79.9000113.8Y26Y24-Y26 PolarHBondContact O-N 2.81Å; Y24-Y26 VanDerWaalsContact O-N 3.1Å
25L61.8Low59.9Low158 Ų158129.2 Ų129.283%0.82770%0.699SS**  trans-86.462.5168-83.4133.4000109.4E27L25-E27 VanDerWaalsContact C-N 3.26Å; L25-E27 PolarHBondContact O-N 2.84Å; L25-E27 VanDerWaalsContact O-N 3.08Å
26Y59.6Low59.9Low216 Ų216131.3 Ų131.385%0.84771%0.705SS**  trans-73.594.5157-141.2-92.4000105.5Y24 N28Y24-Y26 PolarHBondContact O-N 2.81Å; Y24-Y26 VanDerWaalsContact O-N 3.1Å; Y26-N28 PolarHBondContact O-N 3.29Å
27E57.6Low59.9Low175 Ų175131.8 Ų131.882%0.81871%0.708SS**  trans-59.284.7166.5-82.2-177.5136.300108.6L25 N29L25-E27 VanDerWaalsContact C-N 3.26Å; L25-E27 PolarHBondContact O-N 2.84Å; L25-E27 VanDerWaalsContact O-N 3.08Å; E27-N29 PolarHBondContact O-N 3.46Å
28N58.7Low60.1Low120 Ų120135 Ų13564%0.64272%0.721SS**  trans-83.777.8155.7-172.927.7000107.4Y26 S30Y26-N28 PolarHBondContact O-N 3.29Å; N28-S30 PolarHBondContact ND2-OG 2.76Å; N28-S30 PolarHBondContact OD1-OG 3.2Å; N28-S30 PolarHBondContact O-N 2.67Å
29N64.4Low60.5Low116 Ų116138.9 Ų138.962%0.6273%0.726SS**  trans-68.368.1160.9178.514000108.6E27 N31E27-N29 PolarHBondContact O-N 3.46Å; N29-N31 PolarHBondContact O-N 3.08Å; N29-N31 PolarHBondContact OD1-OD1 2.82Å; N29-N31 PolarHBondContact OD1-ND2 3.05Å; N29-N31 WeakPolarHBondContact OD1-CB 3.3Å
30S60.8Low60.8Low83 Ų83137.9 Ų137.958%0.5872%0.721SS**  trans-80.466167.1-81.30000108.8N28 S32N28-S30 PolarHBondContact ND2-OG 2.76Å; N28-S30 PolarHBondContact OD1-OG 3.2Å; N28-S30 PolarHBondContact O-N 2.67Å; S30-S32 PolarHBondContact O-N 2.98Å; S30-S32 VanDerWaalsContact O-N 3.07Å
31N66.6Low61Low139 Ų139137.7 Ų137.774%0.74373%0.726SS**  trans-79.774.3162.5-76.1-9.2000108.9N29N29-N31 PolarHBondContact O-N 3.08Å; N29-N31 PolarHBondContact OD1-OD1 2.82Å; N29-N31 PolarHBondContact OD1-ND2 3.05Å; N29-N31 WeakPolarHBondContact OD1-CB 3.3Å
32S59.3Low61.2Low93 Ų93139.4 Ų139.465%0.6573%0.73SS**  trans-127.988.7146.9-172.90000106.5S30 I34S30-S32 PolarHBondContact O-N 2.98Å; S30-S32 VanDerWaalsContact O-N 3.07Å; S32-I34 PolarHBondContact O-N 2.87Å
33T61.5Low61.5Low128 Ų128140.8 Ų140.879%0.78573%0.731SS**  trans-52.591.7156.9-57.20000106.7A35T33-A35 PolarHBondContact O-N 3.1Å
34I62.5Low61.8Low158 Ų158141.5 Ų141.581%0.8173%0.73SS**  trans-64.2102.1162.2-62.5176.2000103.6S32 E36S32-I34 PolarHBondContact O-N 2.87Å; I34-E36 PolarHBondContact O-N 3.35Å
35A61.1Low62.2Low72 Ų72139.3 Ų139.360%0.59573%0.725SS**  trans-49.2131.9-174.700000109.9T33 N37T33-A35 PolarHBondContact O-N 3.1Å; A35-N37 VanDerWaalsContact C-N 3.26Å; A35-N37 PolarHBondContact O-N 3.42Å
36E60.7Low62.3Low186 Ų186139 Ų13987%0.86972%0.719SS**  trans-47.694.7157.4-72.1176.7144.700109.2I34I34-E36 PolarHBondContact O-N 3.35Å
37N61.8Low62.4Low104 Ų104134.4 Ų134.456%0.55671%0.709SS**  trans-145.443.6157.1-159.274.3000111.2A35 K39A35-N37 VanDerWaalsContact C-N 3.26Å; A35-N37 PolarHBondContact O-N 3.42Å; N37-K39 PolarHBondContact O-N 3.42Å; N37-K39 VanDerWaalsContact OD1-CB 3.32Å; N37-K39 WeakPolarHBondContact OD1-CB 3.22Å; N37-K39 WeakPolarHBondContact OD1-CD 3.36Å; N37-K39 WeakPolarHBondContact OD1-CE 2.98Å; N37-K39 WeakPolarHBondContact OD1-CG 3.35Å
38D61Low62.6Low172 Ų172131.2 Ų131.292%0.9270%0.702SS**  trans-71.944.4140.1-79.2-21.5000109.2N40D38-N40 PolarHBondContact O-N 3.19Å
39K63.5Low63Low146 Ų146135.5 Ų135.564%0.63571%0.71SS**  trans-72.793.6166.4-70.7-171.4-160.11770105N37N37-K39 PolarHBondContact O-N 3.42Å; N37-K39 VanDerWaalsContact OD1-CB 3.32Å; N37-K39 WeakPolarHBondContact OD1-CB 3.22Å; N37-K39 WeakPolarHBondContact OD1-CD 3.36Å; N37-K39 WeakPolarHBondContact OD1-CE 2.98Å; N37-K39 WeakPolarHBondContact OD1-CG 3.35Å
40N63.8Low63Low120 Ų120137.5 Ų137.564%0.64272%0.72SS**  trans48.499.7146.9-49.2-34.1000111.6D38 L42D38-N40 PolarHBondContact O-N 3.19Å; N40-L42 PolarHBondContact O-N 2.84Å; N40-L42 HydrophobicContact CB-CG 4.06Å
41H62Low63.1Low180 Ų180138.5 Ų138.583%0.83373%0.727SS**  trans-61.177.7149.4-167.1-82.1000106.7S43H41-S43 PolarHBondContact O-N 3.29Å
42L63.3Low62.9Low151 Ų151139.4 Ų139.479%0.79173%0.732SS**  trans-61.680.6158.1-78.9168.4000103.3N40 E44N40-L42 PolarHBondContact O-N 2.84Å; N40-L42 HydrophobicContact CB-CG 4.06Å; L42-E44 PolarHBondContact O-N 2.83Å
43S64.9Low63.2Low85 Ų85139.9 Ų139.959%0.59474%0.735SS**  trans-59.296.7161.3-175.50000103.9H41 K45H41-S43 PolarHBondContact O-N 3.29Å; S43-K45 PolarHBondContact O-N 3.36Å
44E65.9Low63.2Low160 Ų160139.2 Ų139.275%0.74874%0.736SS**  trans-50.2117.7172.2-171166.4-171.600106.7L42 Q46L42-E44 PolarHBondContact O-N 2.83Å; E44-Q46 PolarHBondContact O-N 2.93Å; E44-Q46 VanDerWaalsContact O-N 3.1Å
45K64.7Low63Low163 Ų163140 Ų14071%0.70974%0.738SS**  trans-56.9118.4179.6-64.7-171.1174.9-167.60107.5S43 D47S43-K45 PolarHBondContact O-N 3.36Å; K45-D47 VanDerWaalsContact C-N 3.35Å; K45-D47 PolarHBondContact O-N 2.94Å
46Q64.1Low62.8Low152 Ų152145.8 Ų145.871%0.7177%0.774SS**  trans-9485.9153.1-64.6-62.4-2600105.7E44 T48E44-Q46 PolarHBondContact O-N 2.93Å; E44-Q46 VanDerWaalsContact O-N 3.1Å; Q46-T48 PolarHBondContact O-N 2.65Å
47D62.1Low62.9Low119 Ų119143.8 Ų143.864%0.63677%0.769SS**  trans-63.387157.7-70.9-40.4000105.7K45 Y49K45-D47 VanDerWaalsContact C-N 3.35Å; K45-D47 PolarHBondContact O-N 2.94Å; D47-Y49 PolarHBondContact O-N 3.38Å
48T61.9Low63Low108 Ų108145.8 Ų145.866%0.66378%0.781SS**  trans-66.690.5171.7-54.30000106.8Q46 L50Q46-T48 PolarHBondContact O-N 2.65Å; T48-L50 HydrophobicContact CG2-CD2 4.29Å; T48-L50 HydrophobicContact CG2-CG 4.11Å; T48-L50 PolarHBondContact O-N 3Å
49Y66.1Low63.1Low210 Ų210144.4 Ų144.482%0.82477%0.773SS**  trans-57.690.5159.5-103.1-94.8000106.5D47 S51D47-Y49 PolarHBondContact O-N 3.38Å; Y49-S51 PolarHBondContact O-N 3.28Å
50L64.7Low63Low159 Ų159144.3 Ų144.383%0.83278%0.781SS**  trans-6890.2163-79.2171.4000106.3T48 N52T48-L50 HydrophobicContact CG2-CD2 4.29Å; T48-L50 HydrophobicContact CG2-CG 4.11Å; T48-L50 PolarHBondContact O-N 3Å; L50-N52 PolarHBondContact O-N 2.96Å
51S63.9Low63Low104 Ų104145.8 Ų145.873%0.72779%0.79SS**  trans-43131.8170.3-82.60000111.2Y49 S53Y49-S51 PolarHBondContact O-N 3.28Å; S51-S53 PolarHBondContact O-N 3.08Å
52N61.8Low63.1Low158 Ų158143.5 Ų143.585%0.84579%0.787SS**  trans-23.1113.6170.4-57.2-28.2000114.5L50L50-N52 PolarHBondContact O-N 2.96Å
53S65.7Low63Low102 Ų102143 Ų14371%0.71379%0.787SS**  trans-99.997.2154.8160.80000106.9S51 M55S51-S53 PolarHBondContact O-N 3.08Å; S53-M55 PolarHBondContact O-N 3.47Å
54S62.7Low62.9Low115 Ų115147.5 Ų147.580%0.80480%0.801SS**  trans-55.1104.3165.9-57.70000109.1
55M57.6Low62.7Low174 Ų174146.4 Ų146.486%0.85781%0.806SS**  trans-96.5118.4162.6-78-160.270.300108S53S53-M55 PolarHBondContact O-N 3.47Å
56S56.6Low62.5Low193 Ų193144.9 Ų144.9100%1.3582%0.815SS**  trans-580177.5-62.60000114

Retrieved 56 of 56 residues in 34.7 ms (Link to these results)