A0A068BEU0_HUMAN Loading...

Truncated breast and ovarian cancer susceptibility protein 2

AlphaFold DB , UniProt , Accession A0A068BEU0, Species HUMAN (Homo sapiens, Human), Gene BRCA2, Length 33 aa.

						>A0A068BEU0_HUMAN|A0A068BEU0|BRCA2
ISANSTRPARWYTKLGFFPDPRPKSSALIIAFQ
					

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	I	58.7	Low	70	Confident	205 Å²	205	139.9 Å²	139.9	100%	1.051	74%	0.743	S	S	*	*				0	112.6	0	-66.1	167.7	0	0	0	106.9	T6	I1-T6 HydrophobicContact CG2-CG2 4.39Å
2	S	63	Low	69.9	Low	66 Å²	66	138.2 Å²	138.2	46%	0.462	72%	0.72	S	S	.	*			trans	-87.5	117.9	178.1	172.6	0	0	0	0	109.1	N4 S5 T6	S2-N4 PolarHBondContact O-N 3.05Å; S2-S5 VanDerWaalsContact O-N 3.16Å; S2-S5 PolarHBondContact O-N 2.95Å; S2-T6 WeakPolarHBondContact O-CB 3.25Å; S2-T6 PolarHBondContact O-N 3.1Å; S2-T6 PolarHBondContact O-OG1 3.1Å
3	A	69.1	Low	69.8	Low	85 Å²	85	131.8 Å²	131.8	70%	0.702	69%	0.69	S	S	*	*	G	3₁₀ helix	trans	-62.5	-30.2	-177.1	0	0	0	0	0	112.8	S5	A3-S5 VanDerWaalsContact C-N 3.27Å; A3-S5 PolarHBondContact O-N 2.79Å
4	N	77.8	Confident	69.9	Low	164 Å²	164	134.6 Å²	134.6	88%	0.877	69%	0.694	S	S	*	*	G	3₁₀ helix	trans	-76.7	-13.4	179.9	-66.1	-23.7	0	0	0	113.6	S2	S2-N4 PolarHBondContact O-N 3.05Å
5	S	62	Low	69.9	Low	102 Å²	102	138 Å²	138	71%	0.713	71%	0.713	S	S	*	*	G	3₁₀ helix	trans	-115	1.2	-177.8	-50.5	0	0	0	0	113	S2 A3	S2-S5 VanDerWaalsContact O-N 3.16Å; S2-S5 PolarHBondContact O-N 2.95Å; A3-S5 VanDerWaalsContact C-N 3.27Å; A3-S5 PolarHBondContact O-N 2.79Å
6	T	73.1	Confident	69.6	Low	82 Å²	82	134 Å²	134	50%	0.503	72%	0.716	S	S	.	*			trans	-114	107.8	-173.7	-52.6	0	0	0	0	109.1	I1 S2	I1-T6 HydrophobicContact CG2-CG2 4.39Å; S2-T6 WeakPolarHBondContact O-CB 3.25Å; S2-T6 PolarHBondContact O-N 3.1Å; S2-T6 PolarHBondContact O-OG1 3.1Å
7	R	74.6	Confident	69.1	Low	229 Å²	229	135.4 Å²	135.4	86%	0.864	72%	0.715	S	S	*	*	P	Polyproline II helix	trans	-101.1	148.6	170.3	-66.6	-172.6	-175.3	-114.7	1.8	109.6	A9	R7-A9 PolarHBondContact O-N 3.17Å
8	P	73	Confident	69.1	Low	128 Å²	128	137.6 Å²	137.6	83%	0.831	72%	0.717	S	S	*	*	P	Polyproline II helix	trans	-58.8	128.7	178.4	21.8	-31.2	0	0	0	110.8
9	A	72.6	Confident	69.1	Low	80 Å²	80	134.9 Å²	134.9	66%	0.661	71%	0.71	S	S	*	*	P	Polyproline II helix	trans	-70.4	140	173.9	0	0	0	0	0	109.9	R7	R7-A9 PolarHBondContact O-N 3.17Å
10	R	73.3	Confident	69.1	Low	160 Å²	160	132.4 Å²	132.4	60%	0.604	70%	0.697	S	S	*	*	P	Polyproline II helix	trans	-77.1	154.6	176	-64.2	176.2	72.1	-179.8	-7.4	108.7	Y12 T13	R10-Y12 VanDerWaalsContact CZ-CE1 3.4Å; R10-Y12 PolarHBondContact O-N 3.28Å; R10-Y12 PolarHBondContact NH1-OH 3.14Å; R10-Y12 VanDerWaalsContact NE-OH 3.1Å; R10-Y12 PolarHBondContact NE-OH 2.75Å; R10-Y12 HydrophobicContact CG-CE1 4.26Å; R10-Y12 WeakPolarHBondContact CD-OH 3.23Å; R10-Y12 VanDerWaalsContact CD-OH 3.25Å; R10-Y12 HydrophobicContact CB-CE1 3.62Å; R10-Y12 HydrophobicContact CB-CD1 3.97Å; R10-T13 PolarHBondContact N-OG1 3.3Å; R10-T13 VanDerWaalsContact O-CB 3.23Å; R10-T13 WeakPolarHBondContact O-CB 3.23Å; R10-T13 PolarHBondContact O-N 3.33Å; R10-T13 PolarHBondContact O-OG1 2.84Å; R10-T13 VanDerWaalsContact O-OG1 3.1Å
11	W	73.4	Confident	69.1	Low	238 Å²	238	131.7 Å²	131.7	90%	0.902	70%	0.7	S	S	*	*	T	Hydrogen-bonded Turn	trans	-59.2	-20.8	-176.6	62.1	-94.1	0	0	0	114.8
12	Y	68.3	Low	69.7	Low	119 Å²	119	130.9 Å²	130.9	47%	0.467	68%	0.684	S	S	.	*	T	Hydrogen-bonded Turn	trans	-98.6	1.1	175.9	65.1	-97	0	0	0	113.4	R10 K14	R10-Y12 VanDerWaalsContact CZ-CE1 3.4Å; R10-Y12 PolarHBondContact O-N 3.28Å; R10-Y12 PolarHBondContact NH1-OH 3.14Å; R10-Y12 VanDerWaalsContact NE-OH 3.1Å; R10-Y12 PolarHBondContact NE-OH 2.75Å; R10-Y12 HydrophobicContact CG-CE1 4.26Å; R10-Y12 WeakPolarHBondContact CD-OH 3.23Å; R10-Y12 VanDerWaalsContact CD-OH 3.25Å; R10-Y12 HydrophobicContact CB-CE1 3.62Å; R10-Y12 HydrophobicContact CB-CD1 3.97Å; Y12-K14 PolarHBondContact O-N 2.88Å
13	T	68.3	Low	69.5	Low	55 Å²	55	133.3 Å²	133.3	34%	0.337	70%	0.698	S	S	.	*			trans	-70.7	100.1	179	-55.3	0	0	0	0	108.4	R10 L15	R10-T13 PolarHBondContact N-OG1 3.3Å; R10-T13 VanDerWaalsContact O-CB 3.23Å; R10-T13 WeakPolarHBondContact O-CB 3.23Å; R10-T13 PolarHBondContact O-N 3.33Å; R10-T13 PolarHBondContact O-OG1 2.84Å; R10-T13 VanDerWaalsContact O-OG1 3.1Å; T13-L15 PolarHBondContact O-N 2.68Å
14	K	72.3	Confident	69.2	Low	172 Å²	172	137.6 Å²	137.6	75%	0.748	70%	0.701	S	S	*	*			trans	-59.2	122.8	177.7	-167.1	170.7	-175	175	0	109.1	Y12 G16 F17	Y12-K14 PolarHBondContact O-N 2.88Å; K14-G16 PolarHBondContact O-N 3.16Å; K14-F17 VanDerWaalsContact O-N 3.14Å; K14-F17 PolarHBondContact O-N 2.67Å
15	L	69	Low	68.2	Low	185 Å²	185	134.8 Å²	134.8	97%	0.969	69%	0.693	S	S	*	*	T	Hydrogen-bonded Turn	trans	-62.3	17.8	-171.5	-71	170.9	0	0	0	116.7	T13	T13-L15 PolarHBondContact O-N 2.68Å
16	G	65.9	Low	68.1	Low	74 Å²	74	134.3 Å²	134.3	76%	0.763	69%	0.69	S	S	*	*	T	Hydrogen-bonded Turn	trans	-153.4	7.3	177.4	0	0	0	0	0	114.2	K14	K14-G16 PolarHBondContact O-N 3.16Å
17	F	61.3	Low	67.1	Low	158 Å²	158	134.4 Å²	134.4	69%	0.693	70%	0.7	S	S	*	*			trans	-127.5	82.8	-179.5	-153.8	-96.9	0	0	0	110	K14	K14-F17 VanDerWaalsContact O-N 3.14Å; K14-F17 PolarHBondContact O-N 2.67Å
18	F	68.2	Low	66.1	Low	174 Å²	174	128.8 Å²	128.8	76%	0.763	69%	0.686	S	S	*	*			trans	-78.2	121.9	159	-135.8	-94.6	0	0	0	106.3	D20	F18-D20 PolarHBondContact O-N 3.09Å
19	P	69.6	Low	65.1	Low	88 Å²	88	129.8 Å²	129.8	57%	0.571	68%	0.683	S	S	*	*			trans	-56.9	136.8	171.7	25.8	-32	0	0	0	107.6	P21	P19-P21 VanDerWaalsContact O-N 3.13Å
20	D	69.1	Low	64.1	Low	84 Å²	84	133.8 Å²	133.8	45%	0.449	69%	0.691	S	S	.	*			trans	-45	121.4	179.1	-170.4	-30.6	0	0	0	110	F18 R22	F18-D20 PolarHBondContact O-N 3.09Å; D20-R22 IonicContact OD2-CZ 3.08Å; D20-R22 PolarHBondContact OD2-NH2 2.7Å; D20-R22 IonicContact OD2-NH2 2.68Å; D20-R22 PolarHBondContact OD2-NE 3.28Å; D20-R22 IonicContact OD2-NE 2.68Å; D20-R22 PolarHBondContact OD1-NE 3.36Å; D20-R22 IonicContact OD1-NE 3.36Å; D20-R22 PolarHBondContact OD1-N 2.84Å; D20-R22 WeakPolarHBondContact OD1-CG 3.41Å; D20-R22 WeakPolarHBondContact OD1-CB 3.44Å; D20-R22 VanDerWaalsContact OD1-CB 3.23Å; D20-R22 VanDerWaalsContact O-N 3.09Å; D20-R22 PolarHBondContact O-N 2.9Å; D20-R22 VanDerWaalsContact CG-NE 3.3Å
21	P	67.9	Low	63.1	Low	118 Å²	118	129 Å²	129	77%	0.766	69%	0.686	S	S	*	*			trans	-68.7	-4.7	-178	29.7	-36.2	0	0	0	112.5	P19 P23	P19-P21 VanDerWaalsContact O-N 3.13Å; P21-P23 WeakPolarHBondContact O-CD 3.16Å; P21-P23 VanDerWaalsContact O-N 3.12Å
22	R	71.1	Confident	62.2	Low	188 Å²	188	127 Å²	127	71%	0.709	68%	0.684	S	S	*	*	S	Bend	trans	-52.5	120.6	172.8	-79.1	-174.8	-65.2	164.8	0.6	108.8	D20 K24	D20-R22 IonicContact OD2-CZ 3.08Å; D20-R22 PolarHBondContact OD2-NH2 2.7Å; D20-R22 IonicContact OD2-NH2 2.68Å; D20-R22 PolarHBondContact OD2-NE 3.28Å; D20-R22 IonicContact OD2-NE 2.68Å; D20-R22 PolarHBondContact OD1-NE 3.36Å; D20-R22 IonicContact OD1-NE 3.36Å; D20-R22 PolarHBondContact OD1-N 2.84Å; D20-R22 WeakPolarHBondContact OD1-CG 3.41Å; D20-R22 WeakPolarHBondContact OD1-CB 3.44Å; D20-R22 VanDerWaalsContact OD1-CB 3.23Å; D20-R22 VanDerWaalsContact O-N 3.09Å; D20-R22 PolarHBondContact O-N 2.9Å; D20-R22 VanDerWaalsContact CG-NE 3.3Å; R22-K24 PolarHBondContact O-N 2.68Å; R22-K24 VanDerWaalsContact O-N 3.16Å
23	P	60.5	Low	61.3	Low	117 Å²	117	134.4 Å²	134.4	76%	0.76	72%	0.723	S	S	*	*			trans	-54	129.3	170.7	20.9	-29.3	0	0	0	107.1	P21 S25	P21-P23 WeakPolarHBondContact O-CD 3.16Å; P21-P23 VanDerWaalsContact O-N 3.12Å; P23-S25 PolarHBondContact O-N 3.16Å
24	K	61.2	Low	60.9	Low	175 Å²	175	138.4 Å²	138.4	76%	0.761	74%	0.742	S	S	*	*			trans	-49.6	110.2	-179.3	-65.1	-171.3	-173.4	177.6	0	107.5	R22 S26 L28	R22-K24 PolarHBondContact O-N 2.68Å; R22-K24 VanDerWaalsContact O-N 3.16Å; K24-S26 PolarHBondContact O-N 3.39Å; K24-L28 HydrophobicContact CD-CD1 3.7Å
25	S	57.7	Low	60.3	Low	104 Å²	104	136.6 Å²	136.6	73%	0.727	74%	0.742	S	S	*	*			trans	-57.9	101.8	-175.6	-176.2	0	0	0	0	108.7	P23 A27	P23-S25 PolarHBondContact O-N 3.16Å; S25-A27 PolarHBondContact O-N 3.29Å
26	S	59.3	Low	59.9	Low	93 Å²	93	133.9 Å²	133.9	65%	0.65	73%	0.729	S	S	*	*	S	Bend	trans	42.1	-0.8	153.8	54.5	0	0	0	0	121.9	K24	K24-S26 PolarHBondContact O-N 3.39Å
27	A	53.6	Low	59.5	Low	84 Å²	84	137.5 Å²	137.5	69%	0.694	73%	0.727	S	S	*	*	S	Bend	trans	-101.1	2.6	-175.7	0	0	0	0	0	114.3	S25	S25-A27 PolarHBondContact O-N 3.29Å
28	L	52.4	Low	59.4	Low	110 Å²	110	136.2 Å²	136.2	58%	0.576	73%	0.729	S	S	*	*	S	Bend	trans	-119.3	5.8	-179.2	-71.3	173.7	0	0	0	114.5	K24 I30	K24-L28 HydrophobicContact CD-CD1 3.7Å; L28-I30 VanDerWaalsContact C-N 3.33Å
29	I	53.3	Low	58.8	Low	149 Å²	149	133.7 Å²	133.7	76%	0.764	73%	0.727	S	S	*	*	T	Hydrogen-bonded Turn	trans	-81	-13.4	179.7	-62.1	178.1	0	0	0	112
30	I	51.3	Low	58	Low	165 Å²	165	136.9 Å²	136.9	85%	0.846	74%	0.738	S	S	*	*	T	Hydrogen-bonded Turn	trans	-93.5	11	-179.2	-14.1	176	0	0	0	114.1	L28	L28-I30 VanDerWaalsContact C-N 3.33Å
31	A	51.6	Low	57.2	Low	59 Å²	59	141 Å²	141	49%	0.488	76%	0.761	S	S	.	*	S	Bend	trans	-107.9	4.3	-171.1	0	0	0	0	0	115.6
32	F	55.6	Low	56.3	Low	196 Å²	196	142.9 Å²	142.9	86%	0.86	76%	0.76	S	S	*	*			trans	-150.1	78.3	172.9	-65.9	-79.1	0	0	0	109.9
33	Q	48.2	Very low	54.9	Low	275 Å²	275	138.8 Å²	138.8	100%	1.285	77%	0.765	S	S	*	*			trans	-81.7	0	139.9	-82.7	-163	98.6	0	0	107.7

Retrieved 33 of 33 residues in 15.3 ms (Link to these results)

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