A0A068BEV8_HUMAN Loading...

Truncated breast and ovarian cancer susceptibility protein 2

AlphaFold DB , UniProt , Accession A0A068BEV8, Species HUMAN (Homo sapiens, Human), Gene BRCA2, Length 24 aa.

>A0A068BEV8_HUMAN|A0A068BEV8|BRCA2
VQFNQNTNLRVIQKNQEKLLQFQK
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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1V57.3Low75.9Confident195 Ų195128.5 Ų128.5100%1.18265%0.646SS**  0109.60-178.40000107.4F3V1-F3 PolarHBondContact O-N 3.19Å
2Q56.9Low77.4Confident192 Ų192125.3 Ų125.390%0.89763%0.631SS**  trans-77.8118.4-177.3-154.9170.5-10.900108.6N4Q2-N4 PolarHBondContact O-N 3.45Å; Q2-N4 VanDerWaalsContact O-N 3.1Å
3F60.8Low78.8Confident161 Ų161124.5 Ų124.571%0.70662%0.623SS**  trans-73.6103.4-177.2-156.7-111.7000108.6V1 Q5 N8V1-F3 PolarHBondContact O-N 3.19Å; F3-Q5 PolarHBondContact O-N 3.22Å; F3-N8 WeakPolarHBondContact CE1-ND2 3.5Å; F3-N8 WeakPolarHBondContact CZ-ND2 3.4Å; F3-N8 WeakPolarHBondContact CD1-ND2 3.4Å
4N73.5Confident80Confident86 Ų86124.4 Ų124.446%0.4662%0.617SS.*  trans-74.199-176.5-172.4-16.6000109.9Q2 N6 T7 N8Q2-N4 PolarHBondContact O-N 3.45Å; Q2-N4 VanDerWaalsContact O-N 3.1Å; N4-N6 PolarHBondContact O-N 3.04Å; N4-N6 WeakPolarHBondContact OD1-CB 3.38Å; N4-N6 PolarHBondContact OD1-N 3.48Å; N4-T7 VanDerWaalsContact O-N 3.08Å; N4-T7 PolarHBondContact O-N 3.35Å; N4-T7 WeakPolarHBondContact O-CB 3.48Å; N4-N8 PolarHBondContact O-N 3.41Å
5Q70.1Confident81.2Confident146 Ų146122.1 Ų122.168%0.68261%0.608SS**Hα-helixtrans-56.7-30.6178-67.8175.9-27.500112.2F3 T7 N8 L9F3-Q5 PolarHBondContact O-N 3.22Å; Q5-T7 VanDerWaalsContact C-N 3.34Å; Q5-T7 PolarHBondContact O-N 3.11Å; Q5-N8 PolarHBondContact O-N 3.5Å; Q5-L9 WeakPolarHBondContact O-CG 3.35Å; Q5-L9 PolarHBondContact O-N 3.1Å; Q5-L9 VanDerWaalsContact O-N 3.08Å
6N77.4Confident82.2Confident121 Ų121121.8 Ų121.865%0.64760%0.604SS**Hα-helixtrans-67.3-35.2178.4-57-25000111.8N4 R10N4-N6 PolarHBondContact O-N 3.04Å; N4-N6 WeakPolarHBondContact OD1-CB 3.38Å; N4-N6 PolarHBondContact OD1-N 3.48Å; N6-R10 PolarHBondContact O-N 3.49Å; N6-R10 WeakPolarHBondContact O-CB 3.49Å
7T79.7Confident83Confident76 Ų76122.1 Ų122.147%0.46660%0.604SS.*Hα-helixtrans-66.6-40176.1-54.70000111.2N4 Q5 R10 V11N4-T7 VanDerWaalsContact O-N 3.08Å; N4-T7 PolarHBondContact O-N 3.35Å; N4-T7 WeakPolarHBondContact O-CB 3.48Å; Q5-T7 VanDerWaalsContact C-N 3.34Å; Q5-T7 PolarHBondContact O-N 3.11Å; T7-R10 PolarHBondContact O-N 3.08Å; T7-V11 WeakPolarHBondContact O-CG2 3.35Å; T7-V11 PolarHBondContact O-N 3.42Å; T7-V11 VanDerWaalsContact O-N 3.1Å
8N85.3Confident83.8Confident60 Ų60122.4 Ų122.432%0.32160%0.601SS.*Hα-helixtrans-68.8-44.1179.2-72.7-37.6000112.7F3 N4 Q5 R10 V11 I12F3-N8 WeakPolarHBondContact CE1-ND2 3.5Å; F3-N8 WeakPolarHBondContact CZ-ND2 3.4Å; F3-N8 WeakPolarHBondContact CD1-ND2 3.4Å; N4-N8 PolarHBondContact O-N 3.41Å; Q5-N8 PolarHBondContact O-N 3.5Å; N8-R10 PolarHBondContact O-N 3.27Å; N8-V11 PolarHBondContact O-N 3.02Å; N8-V11 VanDerWaalsContact O-N 3.16Å; N8-I12 WeakPolarHBondContact O-CG1 3.49Å; N8-I12 PolarHBondContact O-N 3.26Å; N8-I12 VanDerWaalsContact O-CG1 3.28Å
9L90.2Very high84.5Confident104 Ų104121.2 Ų121.255%0.54560%0.597SS.*Hα-helixtrans-58-41.7176.6-70173.8000111.1Q5 I12 Q13Q5-L9 WeakPolarHBondContact O-CG 3.35Å; Q5-L9 PolarHBondContact O-N 3.1Å; Q5-L9 VanDerWaalsContact O-N 3.08Å; L9-I12 PolarHBondContact O-N 3.27Å; L9-Q13 WeakPolarHBondContact O-CB 3.46Å; L9-Q13 WeakPolarHBondContact O-CG 3.41Å; L9-Q13 PolarHBondContact O-N 3.17Å
10R90.8Very high85.2Confident196 Ų196120.3 Ų120.374%0.7459%0.594SS**Hα-helixtrans-64.3-40.4176.5-171.5178.2-176.9-146.72.8113N6 T7 N8 K14N6-R10 PolarHBondContact O-N 3.49Å; N6-R10 WeakPolarHBondContact O-CB 3.49Å; T7-R10 PolarHBondContact O-N 3.08Å; N8-R10 PolarHBondContact O-N 3.27Å; R10-K14 WeakPolarHBondContact O-CB 3.22Å; R10-K14 PolarHBondContact O-N 3.44Å; R10-K14 VanDerWaalsContact O-N 3.1Å
11V92.6Very high85.7Confident76 Ų76120.5 Ų120.546%0.46159%0.593SS.*Hα-helixtrans-66.4-42.7176.8170.70000111T7 N8 K14 N15T7-V11 WeakPolarHBondContact O-CG2 3.35Å; T7-V11 PolarHBondContact O-N 3.42Å; T7-V11 VanDerWaalsContact O-N 3.1Å; N8-V11 PolarHBondContact O-N 3.02Å; N8-V11 VanDerWaalsContact O-N 3.16Å; V11-K14 PolarHBondContact O-N 3.02Å; V11-N15 VanDerWaalsContact O-N 3.08Å; V11-N15 PolarHBondContact O-N 3.04Å
12I94.6Very high87.6Confident90 Ų90119.7 Ų119.746%0.46257%0.574SS.*Hα-helixtrans-61.5-48.5177.3-67.4164.3000110.4N8 L9 K14 N15 Q16N8-I12 WeakPolarHBondContact O-CG1 3.49Å; N8-I12 PolarHBondContact O-N 3.26Å; N8-I12 VanDerWaalsContact O-CG1 3.28Å; L9-I12 PolarHBondContact O-N 3.27Å; I12-K14 PolarHBondContact O-N 3.42Å; I12-N15 PolarHBondContact O-N 2.95Å; I12-N15 VanDerWaalsContact O-N 3.17Å; I12-Q16 WeakPolarHBondContact O-CG 3.28Å; I12-Q16 PolarHBondContact O-N 3.45Å
13Q95.5Very high89.3Confident115 Ų115117 Ų11754%0.53756%0.562SS.*Hα-helixtrans-56.7-48.8177.3-77.3173.8-22.900112L9 N15 Q16 E17L9-Q13 WeakPolarHBondContact O-CB 3.46Å; L9-Q13 WeakPolarHBondContact O-CG 3.41Å; L9-Q13 PolarHBondContact O-N 3.17Å; Q13-N15 VanDerWaalsContact C-N 3.26Å; Q13-N15 PolarHBondContact O-N 3.08Å; Q13-Q16 PolarHBondContact O-N 3.16Å; Q13-Q16 VanDerWaalsContact O-N 3.16Å; Q13-E17 PolarHBondContact O-N 3.25Å
14K95.9Very high90.4Very high123 Ų123119.4 Ų119.454%0.53557%0.572SS.*Hα-helixtrans-60-35.9178.3-175.8175.5177.5176.80112.7R10 V11 I12 K18R10-K14 WeakPolarHBondContact O-CB 3.22Å; R10-K14 PolarHBondContact O-N 3.44Å; R10-K14 VanDerWaalsContact O-N 3.1Å; V11-K14 PolarHBondContact O-N 3.02Å; I12-K14 PolarHBondContact O-N 3.42Å; K14-K18 WeakPolarHBondContact O-CG 3.41Å; K14-K18 PolarHBondContact O-N 3.4Å
15N96.8Very high91.3Very high91 Ų91121.1 Ų121.149%0.48758%0.578SS.*Hα-helixtrans-75-35.4178.3-72.5-12.6000112.1V11 I12 Q13 K18 L19V11-N15 VanDerWaalsContact O-N 3.08Å; V11-N15 PolarHBondContact O-N 3.04Å; I12-N15 PolarHBondContact O-N 2.95Å; I12-N15 VanDerWaalsContact O-N 3.17Å; Q13-N15 VanDerWaalsContact C-N 3.26Å; Q13-N15 PolarHBondContact O-N 3.08Å; N15-K18 PolarHBondContact O-N 3.34Å; N15-L19 PolarHBondContact O-N 3.08Å
16Q97Very high92.4Very high116 Ų116119.8 Ų119.854%0.54257%0.572SS.*Hα-helixtrans-62.3-44.7173-74.2178.6-9.200111.6I12 Q13 K18 L19 L20I12-Q16 WeakPolarHBondContact O-CG 3.28Å; I12-Q16 PolarHBondContact O-N 3.45Å; Q13-Q16 PolarHBondContact O-N 3.16Å; Q13-Q16 VanDerWaalsContact O-N 3.16Å; Q16-K18 VanDerWaalsContact C-N 3.34Å; Q16-K18 PolarHBondContact O-N 3.46Å; Q16-L19 PolarHBondContact O-N 2.93Å; Q16-L20 WeakPolarHBondContact O-CG 3.42Å; Q16-L20 PolarHBondContact O-N 3.21Å
17E97.1Very high93.2Very high127 Ų127119.7 Ų119.759%0.59357%0.568SS**Hα-helixtrans-58.8-44.9176.3-71.8176.1172.700111.9Q13 L19 L20 Q21Q13-E17 PolarHBondContact O-N 3.25Å; E17-L19 PolarHBondContact O-N 3Å; E17-L20 PolarHBondContact O-N 3.16Å; E17-Q21 WeakPolarHBondContact O-CG 3.37Å; E17-Q21 PolarHBondContact O-N 3.1Å; E17-Q21 VanDerWaalsContact O-N 3.11Å
18K97.3Very high94Very high128 Ų128122.3 Ų122.356%0.55757%0.574SS**Hα-helixtrans-62.6-41.8177.2-74.3178.2174.7-1690112.7K14 N15 Q16 L20 Q21 F22K14-K18 WeakPolarHBondContact O-CG 3.41Å; K14-K18 PolarHBondContact O-N 3.4Å; N15-K18 PolarHBondContact O-N 3.34Å; Q16-K18 VanDerWaalsContact C-N 3.34Å; Q16-K18 PolarHBondContact O-N 3.46Å; K18-L20 VanDerWaalsContact C-N 3.33Å; K18-L20 PolarHBondContact O-N 2.96Å; K18-Q21 PolarHBondContact O-N 3.37Å; K18-F22 PolarHBondContact O-N 3.1Å
19L97.7Very high94.6Very high99 Ų99126.2 Ų126.252%0.51859%0.59SS.*Hα-helixtrans-61.8-43.6178.2-178.663.1000111N15 Q16 E17 Q21 F22 Q23N15-L19 PolarHBondContact O-N 3.08Å; Q16-L19 PolarHBondContact O-N 2.93Å; E17-L19 PolarHBondContact O-N 3Å; L19-Q21 VanDerWaalsContact C-N 3.31Å; L19-Q21 PolarHBondContact O-N 3.29Å; L19-F22 PolarHBondContact O-N 3.21Å; L19-Q23 WeakPolarHBondContact O-CG 2.85Å; L19-Q23 PolarHBondContact O-N 3.03Å
20L97.1Very high94.8Very high103 Ų103127.7 Ų127.754%0.53959%0.593SS.*Hα-helixtrans-63-34.8176.8-71.5169.3000112.8Q16 E17 K18Q16-L20 WeakPolarHBondContact O-CG 3.42Å; Q16-L20 PolarHBondContact O-N 3.21Å; E17-L20 PolarHBondContact O-N 3.16Å; K18-L20 VanDerWaalsContact C-N 3.33Å; K18-L20 PolarHBondContact O-N 2.96Å
21Q95.3Very high95.1Very high125 Ų125122.8 Ų122.858%0.58458%0.582SS**Hα-helixtrans-71.1-36.9174.9-64.9-60.6-3200112.3E17 K18 L19 Q23 K24E17-Q21 WeakPolarHBondContact O-CG 3.37Å; E17-Q21 PolarHBondContact O-N 3.1Å; E17-Q21 VanDerWaalsContact O-N 3.11Å; K18-Q21 PolarHBondContact O-N 3.37Å; L19-Q21 VanDerWaalsContact C-N 3.31Å; L19-Q21 PolarHBondContact O-N 3.29Å; Q21-Q23 VanDerWaalsContact C-N 3.3Å; Q21-Q23 PolarHBondContact O-N 3.43Å; Q21-K24 PolarHBondContact O-N 3.48Å
22F97.4Very high95.3Very high178 Ų178126.4 Ų126.478%0.78159%0.592SS**Hα-helixtrans-68.4-27.7179.2178.1-96.7000113.4K18 L19 K24K18-F22 PolarHBondContact O-N 3.1Å; L19-F22 PolarHBondContact O-N 3.21Å; F22-K24 VanDerWaalsContact C-N 3.35Å
23Q93.1Very high95.4Very high137 Ų137129.4 Ų129.464%0.6460%0.603SS**THydrogen-bonded Turntrans-80.4-11.4-179.2-72.5178-33.500114.5L19 Q21L19-Q23 WeakPolarHBondContact O-CG 2.85Å; L19-Q23 PolarHBondContact O-N 3.03Å; Q21-Q23 VanDerWaalsContact C-N 3.3Å; Q21-Q23 PolarHBondContact O-N 3.43Å
24K84.7Confident95.4Very high211 Ų211130.7 Ų130.792%0.91761%0.608SS**  trans-87.50177.4-70175179.4179.50110.7Q21 F22Q21-K24 PolarHBondContact O-N 3.48Å; F22-K24 VanDerWaalsContact C-N 3.35Å

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