A0A068BFU7_HUMAN Loading...

Truncated breast and ovarian cancer susceptibility protein 2

AlphaFold DB , UniProt , Accession A0A068BFU7, Species HUMAN (Homo sapiens, Human), Gene BRCA2, Length 31 aa.

>A0A068BFU7_HUMAN|A0A068BFU7|BRCA2
YDTEIDRSRRSAIKKIMERDDTAAKTLVLCF
Structure Viewer
Loading PAE data...
(Predicted Aligned Error values between residue pairs)
Error loading PAE data: please refresh the page.

Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1Y56.2Low66.2Low233 Ų233129.3 Ų129.391%0.91461%0.608SS**  0-410-64.9-65.7000114
2D60.1Low67.3Low140 Ų140122.6 Ų122.675%0.74959%0.591SS**Hα-helixtrans-76.3-37.8177.4-160-100.5000113.5E4 I5 D6D2-E4 VanDerWaalsContact C-N 3.34Å; D2-E4 PolarHBondContact O-N 3.29Å; D2-I5 PolarHBondContact O-N 3.38Å; D2-D6 PolarHBondContact O-N 2.74Å; D2-D6 VanDerWaalsContact O-N 3.1Å
3T64.9Low68.2Low108 Ų108119.9 Ų119.966%0.66358%0.58SS**Hα-helixtrans-65.5-30.9179.6440000114.3R7T3-R7 VanDerWaalsContact O-CB 3.32Å; T3-R7 WeakPolarHBondContact O-CB 3.21Å; T3-R7 PolarHBondContact O-N 2.95Å; T3-R7 VanDerWaalsContact O-N 3.08Å
4E65.5Low69Low124 Ų124120.3 Ų120.358%0.57958%0.578SS**Hα-helixtrans-75.5-35.9179.5-67.5173.8104.500111.7D2 S8D2-E4 VanDerWaalsContact C-N 3.34Å; D2-E4 PolarHBondContact O-N 3.29Å; E4-S8 WeakPolarHBondContact O-CB 3.25Å; E4-S8 PolarHBondContact O-N 3.48Å
5I64.3Low69.7Low111 Ų111120.6 Ų120.657%0.56958%0.575SS**Hα-helixtrans-71.6-43.4176.4-63.7-67.6000110.5D2 R7 S8 R9D2-I5 PolarHBondContact O-N 3.38Å; I5-R7 VanDerWaalsContact C-N 3.34Å; I5-R7 PolarHBondContact O-N 3.21Å; I5-S8 PolarHBondContact O-N 3.39Å; I5-R9 VanDerWaalsContact O-CB 3.24Å; I5-R9 WeakPolarHBondContact O-CB 3.25Å; I5-R9 PolarHBondContact O-N 2.86Å
6D65.5Low70.3Confident57 Ų57119.4 Ų119.431%0.30557%0.572SS.*Hα-helixtrans-64.4-40.4177.1178.1-105.2000111.4D2 R10D2-D6 PolarHBondContact O-N 2.74Å; D2-D6 VanDerWaalsContact O-N 3.1Å; D6-R10 WeakPolarHBondContact O-CB 3.27Å; D6-R10 VanDerWaalsContact O-CG 3.23Å; D6-R10 WeakPolarHBondContact O-CG 3.16Å; D6-R10 PolarHBondContact O-N 3.22Å; D6-R10 IonicContact OD1-CZ 2.65Å; D6-R10 IonicContact OD1-NE 3.53Å; D6-R10 PolarHBondContact OD1-NE 3.34Å; D6-R10 IonicContact OD1-NH2 3Å; D6-R10 PolarHBondContact OD1-NH2 3.35Å; D6-R10 IonicContact OD2-NE 2.59Å
7R65.8Low70.8Confident185 Ų185119.9 Ų119.970%0.69858%0.576SS**Hα-helixtrans-66.3-40.8172.9-168.8179.4-176.2-173.31.6112.2T3 I5 S11T3-R7 VanDerWaalsContact O-CB 3.32Å; T3-R7 WeakPolarHBondContact O-CB 3.21Å; T3-R7 PolarHBondContact O-N 2.95Å; T3-R7 VanDerWaalsContact O-N 3.08Å; I5-R7 VanDerWaalsContact C-N 3.34Å; I5-R7 PolarHBondContact O-N 3.21Å; R7-S11 WeakPolarHBondContact O-CB 3.39Å; R7-S11 PolarHBondContact O-N 2.99Å; R7-S11 PolarHBondContact O-OG 3.39Å
8S66.8Low71.1Confident77 Ų77118.9 Ų118.954%0.53857%0.57SS.*Hα-helixtrans-67.6-44.4179.4-173.70000111.6E4 I5 S11 A12E4-S8 WeakPolarHBondContact O-CB 3.25Å; E4-S8 PolarHBondContact O-N 3.48Å; I5-S8 PolarHBondContact O-N 3.39Å; S8-S11 PolarHBondContact O-N 3.46Å; S8-A12 WeakPolarHBondContact O-CB 3.44Å; S8-A12 PolarHBondContact O-N 3.21Å
9R72.3Confident71.4Confident162 Ų162121.9 Ų121.961%0.61158%0.575SS**Hα-helixtrans-67.7-44177.8-161.9174.683.4-169.74.9111.6I5 S11 A12 I13I5-R9 VanDerWaalsContact O-CB 3.24Å; I5-R9 WeakPolarHBondContact O-CB 3.25Å; I5-R9 PolarHBondContact O-N 2.86Å; R9-S11 VanDerWaalsContact C-N 3.27Å; R9-S11 PolarHBondContact O-N 3.32Å; R9-A12 PolarHBondContact O-N 3.4Å; R9-I13 HydrophobicContact CG-CD1 4.23Å; R9-I13 WeakPolarHBondContact O-CG1 3.32Å; R9-I13 PolarHBondContact O-N 3.31Å
10R71.8Confident71.5Confident159 Ų159121 Ų12160%0.657%0.574SS**Hα-helixtrans-60.8-37.9172.2-74.9-169.1-79156.4-5.5111.5D6 K14D6-R10 WeakPolarHBondContact O-CB 3.27Å; D6-R10 VanDerWaalsContact O-CG 3.23Å; D6-R10 WeakPolarHBondContact O-CG 3.16Å; D6-R10 PolarHBondContact O-N 3.22Å; D6-R10 IonicContact OD1-CZ 2.65Å; D6-R10 IonicContact OD1-NE 3.53Å; D6-R10 PolarHBondContact OD1-NE 3.34Å; D6-R10 IonicContact OD1-NH2 3Å; D6-R10 PolarHBondContact OD1-NH2 3.35Å; D6-R10 IonicContact OD2-NE 2.59Å; R10-K14 WeakPolarHBondContact O-CB 3.48Å; R10-K14 PolarHBondContact O-N 3.01Å
11S75.1Confident71.5Confident66 Ų66119.1 Ų119.146%0.46257%0.567SS.*Hα-helixtrans-70.6-37.4177-59.10000112.7R7 S8 R9 K15R7-S11 WeakPolarHBondContact O-CB 3.39Å; R7-S11 PolarHBondContact O-N 2.99Å; R7-S11 PolarHBondContact O-OG 3.39Å; S8-S11 PolarHBondContact O-N 3.46Å; R9-S11 VanDerWaalsContact C-N 3.27Å; R9-S11 PolarHBondContact O-N 3.32Å; S11-K15 VanDerWaalsContact O-CB 3.23Å; S11-K15 WeakPolarHBondContact O-CB 3.3Å; S11-K15 PolarHBondContact O-N 3.4Å
12A79.6Confident72.1Confident49 Ų49112.1 Ų112.141%0.40555%0.549SS..Hα-helixtrans-66.5-47.9176.700000111.5S8 R9 K15 I16S8-A12 WeakPolarHBondContact O-CB 3.44Å; S8-A12 PolarHBondContact O-N 3.21Å; R9-A12 PolarHBondContact O-N 3.4Å; A12-K15 PolarHBondContact O-N 3.48Å; A12-I16 VanDerWaalsContact O-CG1 3.27Å; A12-I16 WeakPolarHBondContact O-CG1 3.34Å; A12-I16 PolarHBondContact O-N 2.87Å
13I78.4Confident72.7Confident88 Ų88108.2 Ų108.245%0.45154%0.536SS..Hα-helixtrans-61.9-46.1176.8-64.6168.4000110.1R9 K15 I16 M17R9-I13 HydrophobicContact CG-CD1 4.23Å; R9-I13 WeakPolarHBondContact O-CG1 3.32Å; R9-I13 PolarHBondContact O-N 3.31Å; I13-K15 VanDerWaalsContact C-N 3.33Å; I13-K15 PolarHBondContact O-N 3.31Å; I13-I16 PolarHBondContact O-N 2.83Å; I13-M17 HydrophobicContact CG2-CG 4.33Å; I13-M17 HydrophobicContact CG2-SD 3.99Å; I13-M17 VanDerWaalsContact O-CG 3.32Å; I13-M17 WeakPolarHBondContact O-CG 3.49Å; I13-M17 PolarHBondContact O-N 2.85Å
14K79.6Confident72.9Confident125 Ų125105.3 Ų105.354%0.54352%0.523SS..Hα-helixtrans-58.2-44.4176.3-175177.7176.8-175.60111.9R10 I16 M17 E18R10-K14 WeakPolarHBondContact O-CB 3.48Å; R10-K14 PolarHBondContact O-N 3.01Å; K14-I16 VanDerWaalsContact C-N 3.33Å; K14-I16 PolarHBondContact O-N 3.27Å; K14-M17 PolarHBondContact O-N 2.65Å; K14-E18 WeakPolarHBondContact CE-OE1 3.31Å; K14-E18 HydrophobicContact CG-CG 4.36Å; K14-E18 WeakPolarHBondContact O-CB 3.23Å; K14-E18 VanDerWaalsContact O-CG 3.26Å; K14-E18 WeakPolarHBondContact O-CG 3.21Å; K14-E18 PolarHBondContact O-N 2.88Å
15K79.5Confident73Confident125 Ų125105.3 Ų105.354%0.54352%0.521SS..Hα-helixtrans-66.3-33.4179.1-166.1174.9-162.1173.80113S11 A12 I13 R19S11-K15 VanDerWaalsContact O-CB 3.23Å; S11-K15 WeakPolarHBondContact O-CB 3.3Å; S11-K15 PolarHBondContact O-N 3.4Å; A12-K15 PolarHBondContact O-N 3.48Å; I13-K15 VanDerWaalsContact C-N 3.33Å; I13-K15 PolarHBondContact O-N 3.31Å; K15-R19 WeakPolarHBondContact O-CG 3.48Å; K15-R19 PolarHBondContact O-N 3.08Å
16I79.9Confident73Confident102 Ų102104 Ų10452%0.52352%0.518SS..Hα-helixtrans-68.1-51172.3-66.6162.4000109.1A12 I13 K14 E18 R19 D20A12-I16 VanDerWaalsContact O-CG1 3.27Å; A12-I16 WeakPolarHBondContact O-CG1 3.34Å; A12-I16 PolarHBondContact O-N 2.87Å; I13-I16 PolarHBondContact O-N 2.83Å; K14-I16 VanDerWaalsContact C-N 3.33Å; K14-I16 PolarHBondContact O-N 3.27Å; I16-E18 VanDerWaalsContact C-N 3.3Å; I16-E18 PolarHBondContact O-N 3.25Å; I16-R19 PolarHBondContact O-N 2.83Å; I16-D20 PolarHBondContact O-N 3.05Å
17M78.4Confident73Confident128 Ų128106.4 Ų106.463%0.63153%0.53SS*.Hα-helixtrans-57.1-40.5177.3-69.1178.274.400112.6I13 K14 R19 D20 D21I13-M17 HydrophobicContact CG2-CG 4.33Å; I13-M17 HydrophobicContact CG2-SD 3.99Å; I13-M17 VanDerWaalsContact O-CG 3.32Å; I13-M17 WeakPolarHBondContact O-CG 3.49Å; I13-M17 PolarHBondContact O-N 2.85Å; K14-M17 PolarHBondContact O-N 2.65Å; M17-R19 VanDerWaalsContact C-N 3.33Å; M17-R19 PolarHBondContact O-N 2.9Å; M17-D20 PolarHBondContact O-N 3.26Å; M17-D21 VanDerWaalsContact O-CB 3.31Å; M17-D21 WeakPolarHBondContact O-CB 3.43Å; M17-D21 PolarHBondContact O-N 3.31Å
18E76.3Confident72.9Confident102 Ų102103 Ų10348%0.47753%0.53SS..Hα-helixtrans-64.7-36176.7-74.9171.7143.400112.3K14 I16 T22K14-E18 WeakPolarHBondContact CE-OE1 3.31Å; K14-E18 HydrophobicContact CG-CG 4.36Å; K14-E18 WeakPolarHBondContact O-CB 3.23Å; K14-E18 VanDerWaalsContact O-CG 3.26Å; K14-E18 WeakPolarHBondContact O-CG 3.21Å; K14-E18 PolarHBondContact O-N 2.88Å; I16-E18 VanDerWaalsContact C-N 3.3Å; I16-E18 PolarHBondContact O-N 3.25Å; E18-T22 PolarHBondContact O-N 3.41Å; E18-T22 PolarHBondContact O-OG1 2.92Å
19R77.3Confident72.8Confident176 Ų176106.3 Ų106.366%0.66454%0.541SS*.Hα-helixtrans-73.9-41.6174.3-75.7176.6178.6-157.4-3.2112.1K15 I16 M17 T22 A23K15-R19 WeakPolarHBondContact O-CG 3.48Å; K15-R19 PolarHBondContact O-N 3.08Å; I16-R19 PolarHBondContact O-N 2.83Å; M17-R19 VanDerWaalsContact C-N 3.33Å; M17-R19 PolarHBondContact O-N 2.9Å; R19-T22 WeakPolarHBondContact O-CB 3.24Å; R19-T22 PolarHBondContact O-N 3.25Å; R19-A23 WeakPolarHBondContact O-CB 3.33Å; R19-A23 PolarHBondContact O-N 2.59Å
20D72.8Confident72.1Confident103 Ų103103.7 Ų103.755%0.55155%0.546SS*.Hα-helixtrans-64-41176.5-105.1-82.6000111.5I16 M17 T22 A23 A24I16-D20 PolarHBondContact O-N 3.05Å; M17-D20 PolarHBondContact O-N 3.26Å; D20-T22 VanDerWaalsContact C-N 3.28Å; D20-T22 PolarHBondContact O-N 2.74Å; D20-A23 PolarHBondContact O-N 2.91Å; D20-A24 WeakPolarHBondContact O-CB 3.27Å; D20-A24 PolarHBondContact O-N 2.96Å
21D70.9Confident71.3Confident82 Ų82107 Ų10744%0.43957%0.566SS.*Hα-helixtrans-61-39.3174.3179.5-99.5000111.6M17 K25M17-D21 VanDerWaalsContact O-CB 3.31Å; M17-D21 WeakPolarHBondContact O-CB 3.43Å; M17-D21 PolarHBondContact O-N 3.31Å; D21-K25 WeakPolarHBondContact O-CB 3.47Å; D21-K25 WeakPolarHBondContact O-CD 3.18Å; D21-K25 VanDerWaalsContact O-CG 3.25Å; D21-K25 WeakPolarHBondContact O-CG 3.43Å; D21-K25 PolarHBondContact O-N 3.29Å; D21-K25 WeakPolarHBondContact OD1-CE 3.4Å; D21-K25 IonicContact OD1-NZ 3.77Å; D21-K25 PolarHBondContact OD1-NZ 2.92Å; D21-K25 IonicContact OD2-NZ 2.74Å
22T70.1Confident71.1Confident86 Ų86109.1 Ų109.153%0.52857%0.571SS.*Hα-helixtrans-65.6-47.2174.1-55.80000111.2E18 R19 D20 A24 K25 T26E18-T22 PolarHBondContact O-N 3.41Å; E18-T22 PolarHBondContact O-OG1 2.92Å; R19-T22 WeakPolarHBondContact O-CB 3.24Å; R19-T22 PolarHBondContact O-N 3.25Å; D20-T22 VanDerWaalsContact C-N 3.28Å; D20-T22 PolarHBondContact O-N 2.74Å; T22-A24 VanDerWaalsContact C-N 3.35Å; T22-A24 PolarHBondContact O-N 3Å; T22-K25 PolarHBondContact O-N 2.78Å; T22-T26 PolarHBondContact O-N 2.96Å; T22-T26 PolarHBondContact O-OG1 3.1Å; T22-T26 VanDerWaalsContact O-OG1 3.08Å
23A71.9Confident70.6Confident57 Ų57112.3 Ų112.347%0.47158%0.58SS.*Hα-helixtrans-64-39.4178.800000112.1R19 D20 T26 L27R19-A23 WeakPolarHBondContact O-CB 3.33Å; R19-A23 PolarHBondContact O-N 2.59Å; D20-A23 PolarHBondContact O-N 2.91Å; A23-T26 PolarHBondContact O-N 2.83Å; A23-L27 WeakPolarHBondContact O-CB 3.32Å; A23-L27 PolarHBondContact O-N 3.35Å
24A70.2Confident70.2Confident48 Ų48113.6 Ų113.640%0.39759%0.587SS.*Hα-helixtrans-64.4-45.1176.100000111.1D20 T22 T26 L27 V28D20-A24 WeakPolarHBondContact O-CB 3.27Å; D20-A24 PolarHBondContact O-N 2.96Å; T22-A24 VanDerWaalsContact C-N 3.35Å; T22-A24 PolarHBondContact O-N 3Å; A24-T26 VanDerWaalsContact C-N 3.3Å; A24-T26 PolarHBondContact O-N 3.44Å; A24-L27 PolarHBondContact O-N 3.36Å; A24-V28 VanDerWaalsContact O-CG2 3.25Å; A24-V28 WeakPolarHBondContact O-CG2 3.14Å; A24-V28 PolarHBondContact O-N 3.26Å
25K65.9Low69.6Low124 Ų124112.9 Ų112.954%0.53959%0.589SS.*Hα-helixtrans-60.3-39.6174.2-74.9167.8179167.20112.2D21 T22 L29D21-K25 WeakPolarHBondContact O-CB 3.47Å; D21-K25 WeakPolarHBondContact O-CD 3.18Å; D21-K25 VanDerWaalsContact O-CG 3.25Å; D21-K25 WeakPolarHBondContact O-CG 3.43Å; D21-K25 PolarHBondContact O-N 3.29Å; D21-K25 WeakPolarHBondContact OD1-CE 3.4Å; D21-K25 IonicContact OD1-NZ 3.77Å; D21-K25 PolarHBondContact OD1-NZ 2.92Å; D21-K25 IonicContact OD2-NZ 2.74Å; T22-K25 PolarHBondContact O-N 2.78Å; K25-L29 WeakPolarHBondContact O-CD1 3.26Å; K25-L29 VanDerWaalsContact O-CG 3.3Å; K25-L29 WeakPolarHBondContact O-CG 3.23Å; K25-L29 PolarHBondContact O-N 3.27Å
26T64.5Low69Low83 Ų83112.2 Ų112.251%0.50959%0.592SS.*Hα-helixtrans-66.9-41.5175-57.10000112T22 A23 A24 L29 C30T22-T26 PolarHBondContact O-N 2.96Å; T22-T26 PolarHBondContact O-OG1 3.1Å; T22-T26 VanDerWaalsContact O-OG1 3.08Å; A23-T26 PolarHBondContact O-N 2.83Å; A24-T26 VanDerWaalsContact C-N 3.3Å; A24-T26 PolarHBondContact O-N 3.44Å; T26-L29 PolarHBondContact O-N 2.86Å; T26-C30 PolarHBondContact O-N 2.63Å
27L66.2Low68.3Low107 Ų107112.9 Ų112.956%0.5660%0.597SS**Hα-helixtrans-64.9-41179.5-168.272.9000111.9A23 A24 L29 C30 F31A23-L27 WeakPolarHBondContact O-CB 3.32Å; A23-L27 PolarHBondContact O-N 3.35Å; A24-L27 PolarHBondContact O-N 3.36Å; L27-L29 VanDerWaalsContact C-N 3.27Å; L27-L29 PolarHBondContact O-N 3.48Å; L27-C30 PolarHBondContact O-N 3.08Å; L27-F31 HydrophobicContact CD1-CE2 4.05Å; L27-F31 HydrophobicContact CD1-CZ 4.43Å; L27-F31 HydrophobicContact CD2-CE2 4.18Å; L27-F31 HydrophobicContact CG-CD2 4.41Å; L27-F31 HydrophobicContact CG-CE2 3.72Å; L27-F31 VanDerWaalsContact O-CD2 3.27Å; L27-F31 WeakPolarHBondContact O-CD2 3.22Å
28V63.6Low67.6Low114 Ų114111.8 Ų111.869%0.69159%0.594SS**Hα-helixtrans-66.7-27.9178.9174.40000112.4A24A24-V28 VanDerWaalsContact O-CG2 3.25Å; A24-V28 WeakPolarHBondContact O-CG2 3.14Å; A24-V28 PolarHBondContact O-N 3.26Å
29L65.1Low66.9Low147 Ų147112.5 Ų112.577%0.7760%0.603SS**Hα-helixtrans-83.5-10.1179.1-69.9170.1000113.9K25 T26 L27K25-L29 WeakPolarHBondContact O-CD1 3.26Å; K25-L29 VanDerWaalsContact O-CG 3.3Å; K25-L29 WeakPolarHBondContact O-CG 3.23Å; K25-L29 PolarHBondContact O-N 3.27Å; T26-L29 PolarHBondContact O-N 2.86Å; L27-L29 VanDerWaalsContact C-N 3.27Å; L27-L29 PolarHBondContact O-N 3.48Å
30C57.6Low66Low106 Ų106107.3 Ų107.372%0.71660%0.598SS**THydrogen-bonded Turntrans-112.714-177.1-69.30000114.3T26 L27T26-C30 PolarHBondContact O-N 2.63Å; L27-C30 PolarHBondContact O-N 3.08Å
31F53.5Low65.4Low230 Ų230107.6 Ų107.6100%1.00960%0.603SS**  trans-1000165.8-76.7-66000111.8L27L27-F31 HydrophobicContact CD1-CE2 4.05Å; L27-F31 HydrophobicContact CD1-CZ 4.43Å; L27-F31 HydrophobicContact CD2-CE2 4.18Å; L27-F31 HydrophobicContact CG-CD2 4.41Å; L27-F31 HydrophobicContact CG-CE2 3.72Å; L27-F31 VanDerWaalsContact O-CD2 3.27Å; L27-F31 WeakPolarHBondContact O-CD2 3.22Å

Retrieved 31 of 31 residues in 18.7 ms (Link to these results)