A0A068BI47_HUMAN Loading...

Truncated breast and ovarian cancer susceptibility protein 2

AlphaFold DB , UniProt , Accession A0A068BI47, Species HUMAN (Homo sapiens, Human), Gene BRCA2, Length 32 aa.

>A0A068BI47_HUMAN|A0A068BI47|BRCA2
FGGSFRTASNKEIKLSEHNIKKSKMFFKDIEE
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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1F52.8Low83.2Confident268 Ų268119.2 Ų119.2100%1.17570%0.698SS**  0101.30-65.6-85.3000108.5G3F1-G3 VanDerWaalsContact O-N 3.08Å; F1-G3 PolarHBondContact O-N 3.37Å
2G54.4Low84Confident79 Ų79118.7 Ų118.781%0.81468%0.684SS**  trans-7594.9-174.900000112.5S4G2-S4 PolarHBondContact O-N 3.02Å; G2-S4 VanDerWaalsContact C-N 3.3Å
3G69.1Low84.7Confident84 Ų84115.8 Ų115.887%0.86666%0.664SS**SBendtrans2514.1145.100000125.8F1F1-G3 VanDerWaalsContact O-N 3.08Å; F1-G3 PolarHBondContact O-N 3.37Å
4S81.3Confident85.3Confident66 Ų66121 Ų12146%0.46268%0.675SS.*  trans-124.8140.7-179.7-61.30000113.3G2G2-S4 PolarHBondContact O-N 3.02Å; G2-S4 VanDerWaalsContact C-N 3.3Å
5F92.2Very high85.6Confident157 Ų157120.4 Ų120.469%0.68967%0.669SS**  trans-66.9135.2173.3-66.9-83.1000111I13F5-I13 HydrophobicContact CB-CD1 4.2Å; F5-I13 PolarHBondContact O-N 3.2Å; F5-I13 HydrophobicContact CB-CB 4.13Å
6R93.9Very high86.2Confident144 Ų144116.3 Ų116.354%0.54365%0.651SS.*BIsolated β-bridgetrans-134.2151.3177.1-62.9-169.4174.6-177.2-2111.2N10 K11R6-N10 WeakPolarHBondContact CD-OD1 3.48Å; R6-N10 PolarHBondContact NH1-OD1 3.32Å; R6-K11 CarbonylContact C-O 3.48Å; R6-K11 WeakPolarHBondContact CA-O 3.26Å
7T94.4Very high86.7Confident54 Ų54119.5 Ų119.533%0.33166%0.66SS.*  trans-71.6164.9171.169.30000110.7S9 N10 K11 I13T7-S9 PolarHBondContact OG1-N 3.12Å; T7-S9 PolarHBondContact OG1-OG 3.09Å; T7-S9 VanDerWaalsContact O-N 3.13Å; T7-S9 PolarHBondContact O-N 3.08Å; T7-N10 WeakPolarHBondContact O-CA 3.48Å; T7-N10 PolarHBondContact O-N 3.3Å; T7-K11 HydrophobicContact CG2-CB 4.2Å; T7-K11 PolarHBondContact N-O 3.26Å; T7-K11 WeakPolarHBondContact OG1-CB 3.24Å; T7-K11 PolarHBondContact OG1-N 3.21Å; T7-I13 HydrophobicContact CG2-CG1 4.06Å; T7-I13 HydrophobicContact CG2-CD1 4.35Å
8A95.7Very high87.3Confident121 Ų121120.4 Ų120.4100%166%0.658SS**THydrogen-bonded Turntrans-59-22.7172.600000113.4N10A8-N10 VanDerWaalsContact C-N 3.28Å
9S96.4Very high87.7Confident85 Ų85119.1 Ų119.159%0.59465%0.65SS**THydrogen-bonded Turntrans-89.516.9172.353.40000113.7T7 K11T7-S9 PolarHBondContact OG1-N 3.12Å; T7-S9 PolarHBondContact OG1-OG 3.09Å; T7-S9 VanDerWaalsContact O-N 3.13Å; T7-S9 PolarHBondContact O-N 3.08Å; S9-K11 VanDerWaalsContact C-N 3.25Å; S9-K11 PolarHBondContact O-N 3.29Å
10N92.2Very high88Confident108 Ų108116.2 Ų116.258%0.57863%0.633SS**SBendtrans61.423.9178-165.737.7000115R6 T7 A8R6-N10 WeakPolarHBondContact CD-OD1 3.48Å; R6-N10 PolarHBondContact NH1-OD1 3.32Å; T7-N10 WeakPolarHBondContact O-CA 3.48Å; T7-N10 PolarHBondContact O-N 3.3Å; A8-N10 VanDerWaalsContact C-N 3.28Å
11K92.7Very high88.4Confident145 Ų145117.7 Ų117.763%0.6363%0.634SS**  trans-84.1136.3171.6-61.8178.1176.7175.90109.5R6 T7 S9R6-K11 CarbonylContact C-O 3.48Å; R6-K11 WeakPolarHBondContact CA-O 3.26Å; T7-K11 HydrophobicContact CG2-CB 4.2Å; T7-K11 PolarHBondContact N-O 3.26Å; T7-K11 WeakPolarHBondContact OG1-CB 3.24Å; T7-K11 PolarHBondContact OG1-N 3.21Å; S9-K11 VanDerWaalsContact C-N 3.25Å; S9-K11 PolarHBondContact O-N 3.29Å
12E93.1Very high90.4Very high113 Ų113111.9 Ų111.953%0.52861%0.608SS.*BIsolated β-bridgetrans-69.2137.4175.3-173.8170-156.100111.6
13I93Very high92.3Very high82 Ų82110.8 Ų110.842%0.42159%0.588SS.*  trans-91.6113.5174.1-60.6178.8000108.2F5 T7 L15F5-I13 HydrophobicContact CB-CD1 4.2Å; F5-I13 PolarHBondContact O-N 3.2Å; F5-I13 HydrophobicContact CB-CB 4.13Å; T7-I13 HydrophobicContact CG2-CG1 4.06Å; T7-I13 HydrophobicContact CG2-CD1 4.35Å; I13-L15 HydrophobicContact CG2-CD2 4.17Å
14K92.8Very high93.4Very high188 Ų188113.4 Ų113.482%0.81758%0.575SS**PPolyproline II helixtrans-87125.9173.9-65.2-175.1179.6-177.50110.2
15L90.9Very high94.1Very high112 Ų112115.2 Ų115.259%0.58658%0.578SS**PPolyproline II helixtrans-97.3144.9175.5-59.4177.9000110.1I13 I20I13-L15 HydrophobicContact CG2-CD2 4.17Å; L15-I20 HydrophobicContact CB-CD1 3.94Å; L15-I20 HydrophobicContact CB-CG1 4.08Å; L15-I20 HydrophobicContact CD1-CG1 4.44Å
16S94.5Very high94.2Very high54 Ų54114.9 Ų114.938%0.37858%0.576SS.*PPolyproline II helixtrans-82.1143.6172.469.50000110.9H18 N19 I20S16-H18 PolarHBondContact O-N 3.06Å; S16-N19 VanDerWaalsContact O-N 3.15Å; S16-N19 VanDerWaalsContact OG-ND2 3.1Å; S16-N19 PolarHBondContact OG-ND2 3.49Å; S16-N19 PolarHBondContact OG-N 3.47Å; S16-N19 VanDerWaalsContact OG-CG 3.28Å; S16-N19 WeakPolarHBondContact OG-CB 3.28Å; S16-N19 PolarHBondContact O-N 3.38Å; S16-I20 WeakPolarHBondContact O-CG1 3.4Å; S16-I20 PolarHBondContact O-N 3.1Å; S16-I20 VanDerWaalsContact O-N 3.1Å
17E95.3Very high94.1Very high171 Ų171112.6 Ų112.680%0.79957%0.57SS**Hα-helixtrans-58-37.6177.3-65.3-177.4169.800112.4N19 I20 K21E17-N19 PolarHBondContact O-N 2.89Å; E17-N19 VanDerWaalsContact C-N 3.35Å; E17-I20 PolarHBondContact O-N 3.35Å; E17-K21 PolarHBondContact O-N 3.1Å
18H97.3Very high94.1Very high136 Ų136115.3 Ų115.363%0.6358%0.578SS**Hα-helixtrans-56.9-47.3176.4179.481000111.9S16 K21 K22S16-H18 PolarHBondContact O-N 3.06Å; H18-K21 PolarHBondContact O-N 2.99Å; H18-K22 WeakPolarHBondContact O-CB 3.49Å; H18-K22 PolarHBondContact O-N 3.31Å
19N94.7Very high93.7Very high95 Ų95116.2 Ų116.251%0.50857%0.566SS.*Hα-helixtrans-71.7-35.1-178.8-71.9-21.7000111.8S16 E17 K22 S23S16-N19 VanDerWaalsContact O-N 3.15Å; S16-N19 VanDerWaalsContact OG-ND2 3.1Å; S16-N19 PolarHBondContact OG-ND2 3.49Å; S16-N19 PolarHBondContact OG-N 3.47Å; S16-N19 VanDerWaalsContact OG-CG 3.28Å; S16-N19 WeakPolarHBondContact OG-CB 3.28Å; S16-N19 PolarHBondContact O-N 3.38Å; E17-N19 PolarHBondContact O-N 2.89Å; E17-N19 VanDerWaalsContact C-N 3.35Å; N19-K22 PolarHBondContact O-N 3.38Å; N19-S23 PolarHBondContact O-N 3.15Å; N19-S23 PolarHBondContact O-OG 2.92Å
20I93.8Very high93.4Very high62 Ų62118.1 Ų118.132%0.31857%0.568SS.*Hα-helixtrans-62.3-44.6173.3-65.9164.9000110.7L15 S16 E17 K22 S23 K24L15-I20 HydrophobicContact CB-CD1 3.94Å; L15-I20 HydrophobicContact CB-CG1 4.08Å; L15-I20 HydrophobicContact CD1-CG1 4.44Å; S16-I20 WeakPolarHBondContact O-CG1 3.4Å; S16-I20 PolarHBondContact O-N 3.1Å; S16-I20 VanDerWaalsContact O-N 3.1Å; E17-I20 PolarHBondContact O-N 3.35Å; I20-K22 VanDerWaalsContact C-N 3.33Å; I20-K22 PolarHBondContact O-N 3.02Å; I20-S23 PolarHBondContact O-N 3.43Å; I20-S23 PolarHBondContact O-OG 3.28Å; I20-K24 HydrophobicContact CG2-CD 4.43Å; I20-K24 WeakPolarHBondContact O-CG 3.44Å; I20-K24 PolarHBondContact O-N 3.08Å; I20-K24 VanDerWaalsContact O-N 3.09Å
21K95.4Very high92.7Very high148 Ų148120.7 Ų120.764%0.64358%0.577SS**Hα-helixtrans-63.6-41.5177.5-176.1176.41791790111.3E17 H18 M25E17-K21 PolarHBondContact O-N 3.1Å; H18-K21 PolarHBondContact O-N 2.99Å; K21-M25 WeakPolarHBondContact O-CG 3.41Å; K21-M25 PolarHBondContact O-N 2.79Å
22K96Very high90.9Very high146 Ų146124.9 Ų124.964%0.63560%0.598SS**Hα-helixtrans-65.3-43.7178.2-172.1175.9-179.7179.80112.1H18 N19 I20 M25 F26H18-K22 WeakPolarHBondContact O-CB 3.49Å; H18-K22 PolarHBondContact O-N 3.31Å; N19-K22 PolarHBondContact O-N 3.38Å; I20-K22 VanDerWaalsContact C-N 3.33Å; I20-K22 PolarHBondContact O-N 3.02Å; K22-M25 PolarHBondContact O-N 3.26Å; K22-F26 VanDerWaalsContact O-N 3.12Å; K22-F26 PolarHBondContact O-N 3.06Å
23S93.6Very high90.8Very high55 Ų55125.5 Ų125.539%0.38560%0.602SS.*Hα-helixtrans-64.6-43.4178.665.90000111.7N19 I20 M25 F26 F27N19-S23 PolarHBondContact O-N 3.15Å; N19-S23 PolarHBondContact O-OG 2.92Å; I20-S23 PolarHBondContact O-N 3.43Å; I20-S23 PolarHBondContact O-OG 3.28Å; S23-M25 VanDerWaalsContact C-N 3.27Å; S23-M25 PolarHBondContact O-N 3.39Å; S23-F26 WeakPolarHBondContact O-CB 3.45Å; S23-F26 PolarHBondContact O-N 2.85Å; S23-F26 VanDerWaalsContact O-N 3.08Å; S23-F27 VanDerWaalsContact O-CD2 3.26Å; S23-F27 WeakPolarHBondContact O-CD2 3.43Å; S23-F27 PolarHBondContact O-N 3.13Å
24K93.4Very high90.7Very high140 Ų140127.7 Ų127.761%0.60961%0.611SS**Hα-helixtrans-56-41174.4-76-179.4176.7-174.50112.6I20 K28I20-K24 HydrophobicContact CG2-CD 4.43Å; I20-K24 WeakPolarHBondContact O-CG 3.44Å; I20-K24 PolarHBondContact O-N 3.08Å; I20-K24 VanDerWaalsContact O-N 3.09Å; K24-K28 WeakPolarHBondContact O-CG 3.21Å; K24-K28 VanDerWaalsContact O-CG 3.28Å
25M94.3Very high90.6Very high104 Ų104124.4 Ų124.451%0.51260%0.6SS.*Hα-helixtrans-66.7-36.8176.8-73.1-72.5-172.100112.7K21 K22 S23 K28K21-M25 WeakPolarHBondContact O-CG 3.41Å; K21-M25 PolarHBondContact O-N 2.79Å; K22-M25 PolarHBondContact O-N 3.26Å; S23-M25 VanDerWaalsContact C-N 3.27Å; S23-M25 PolarHBondContact O-N 3.39Å; M25-K28 WeakPolarHBondContact O-CG 3.19Å; M25-K28 HydrophobicContact SD-CD 3.81Å; M25-K28 WeakPolarHBondContact SD-CE 3.41Å; M25-K28 PolarHBondContact SD-NZ 2.95Å
26F93.9Very high90.5Very high150 Ų150125.1 Ų125.166%0.65860%0.601SS**Hα-helixtrans-67.8-35.5-177-179.5-99.5000113.1K22 S23K22-F26 VanDerWaalsContact O-N 3.12Å; K22-F26 PolarHBondContact O-N 3.06Å; S23-F26 WeakPolarHBondContact O-CB 3.45Å; S23-F26 PolarHBondContact O-N 2.85Å; S23-F26 VanDerWaalsContact O-N 3.08Å
27F93.6Very high90.3Very high95 Ų95129.6 Ų129.642%0.41761%0.614SS.*THydrogen-bonded Turntrans-93.75.9-178-66.8-73000114.2S23 D29 I30 E31S23-F27 VanDerWaalsContact O-CD2 3.26Å; S23-F27 WeakPolarHBondContact O-CD2 3.43Å; S23-F27 PolarHBondContact O-N 3.13Å; F27-D29 PolarHBondContact O-N 3.35Å; F27-I30 HydrophobicContact CD1-CD1 3.83Å; F27-I30 HydrophobicContact CE1-CD1 4.43Å; F27-I30 PolarHBondContact O-N 2.82Å; F27-E31 PolarHBondContact O-N 2.99Å
28K93.3Very high89.9Confident111 Ų111126.8 Ų126.848%0.48360%0.602SS.*G310 helixtrans-54.8-40-177.2-77.1-174.2164.6-169.50113.4K24 M25 I30K24-K28 WeakPolarHBondContact O-CG 3.21Å; K24-K28 VanDerWaalsContact O-CG 3.28Å; M25-K28 WeakPolarHBondContact O-CG 3.19Å; M25-K28 HydrophobicContact SD-CD 3.81Å; M25-K28 WeakPolarHBondContact SD-CE 3.41Å; M25-K28 PolarHBondContact SD-NZ 2.95Å; K28-I30 PolarHBondContact O-N 2.86Å
29D88.1Confident89.4Confident140 Ų140126.1 Ų126.175%0.74960%0.6SS**G310 helixtrans-78.9-4.9-175.7-49.7-32.8000112.8F27F27-D29 PolarHBondContact O-N 3.35Å
30I90Very high89Confident125 Ų125128.5 Ų128.564%0.64161%0.607SS**G310 helixtrans-103.7-20.1179.6-66.8163.2000111.5F27 K28F27-I30 HydrophobicContact CD1-CD1 3.83Å; F27-I30 HydrophobicContact CE1-CD1 4.43Å; F27-I30 PolarHBondContact O-N 2.82Å; K28-I30 PolarHBondContact O-N 2.86Å
31E76.3Confident88.6Confident163 Ų163134.1 Ų134.176%0.76263%0.631SS**  trans-87.7-3179.3-69.2-179.7172.200113.6F27F27-E31 PolarHBondContact O-N 2.99Å
32E55.7Low88Confident232 Ų232132.8 Ų132.8100%1.08463%0.63SS**  trans-91.80174.4-170.2167.3-154.900112.2

Retrieved 32 of 32 residues in 15.1 ms (Link to these results)