A0A068F753_HUMAN Loading...

Glucosylceramidase

AlphaFold DB , UniProt , Accession A0A068F753, Species HUMAN (Homo sapiens, Human), Gene n/a, Length 453 aa.

Structure Viewer
Loading PAE data...
(Predicted Aligned Error values between residue pairs)
Error loading PAE data: please refresh the page.

Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M73.3Confident39.6Very low30 Ų30104 Ų10415%0.14855%0.546CS..  0137.90-58.6176.1-167.100108.1L392 V393 L400 A402 L426 T427 K429M1-L392 HydrophobicContact CB-CD1 3.64Å; M1-L392 HydrophobicContact CB-CG 4Å; M1-L392 HydrophobicContact SD-CD2 3.8Å; M1-L392 HydrophobicContact SD-CG 4.2Å; M1-V393 CarbonylContact C-O 3.58Å; M1-V393 WeakPolarHBondContact CA-O 3.34Å; M1-L400 HydrophobicContact CE-CB 4.14Å; M1-L400 HydrophobicContact CE-CD1 3.79Å; M1-A402 HydrophobicContact CE-CB 3.87Å; M1-A402 HydrophobicContact SD-CB 3.71Å; M1-L426 HydrophobicContact CE-CD1 4.31Å; M1-T427 PolarHBondContact N-O 2.98Å; M1-K429 PolarHBondContact O-N 3.46Å
2E53.3Low38.5Very low91 Ų91103.9 Ų103.943%0.42556%0.556SS.*EExtended strand (participates in β ladder)trans-110.7126.9-177.8-176.8162.6-152.100110.9L392 V393 K429E2-L392 WeakPolarHBondContact O-CA 3.39Å; E2-V393 PolarHBondContact N-O 3.38Å; E2-V393 PolarHBondContact O-N 2.84Å; E2-K429 HydrophobicContact CG-CD 4.1Å; E2-K429 WeakPolarHBondContact OE1-CE 3.27Å; E2-K429 IonicContact OE1-NZ 4Å; E2-K429 PolarHBondContact OE1-NZ 3.31Å
3F50.1Low37.5Very low1 Ų1110.6 Ų110.60%0.00458%0.577CS.*EExtended strand (participates in β ladder)trans-81125.9176.7-156.6-89.4000108.8V390 A404 M406 A412 V414 K429 P431 W450F3-V390 HydrophobicContact CD1-CG2 4.31Å; F3-V390 HydrophobicContact CD2-CG2 4.41Å; F3-V390 HydrophobicContact CE1-CG2 3.61Å; F3-V390 HydrophobicContact CE2-CG2 3.75Å; F3-V390 HydrophobicContact CZ-CG2 3.31Å; F3-A404 HydrophobicContact CD2-CB 3.9Å; F3-A404 HydrophobicContact CE2-CB 3.64Å; F3-M406 HydrophobicContact CE1-CG 4.07Å; F3-M406 HydrophobicContact CE1-SD 4.21Å; F3-M406 HydrophobicContact CZ-CG 3.84Å; F3-A412 HydrophobicContact CE2-CB 4.13Å; F3-A412 HydrophobicContact CZ-CB 3.96Å; F3-V414 HydrophobicContact CD2-CG2 4.4Å; F3-V414 HydrophobicContact CE2-CG2 4.27Å; F3-K429 WeakPolarHBondContact CB-O 3.47Å; F3-K429 PolarHBondContact N-O 2.86Å; F3-P431 WeakPolarHBondContact O-CD 3.34Å; F3-P431 VanDerWaalsContact O-CG 3.28Å; F3-P431 WeakPolarHBondContact O-CG 2.88Å; F3-W450 HydrophobicContact CD2-CH2 4.47Å; F3-W450 HydrophobicContact CD2-CZ2 4.31Å; F3-W450 HydrophobicContact CE2-CH2 4.47Å; F3-W450 HydrophobicContact CE2-CZ2 4.33Å
4S43.2Very low37.2Very low51 Ų51108.6 Ų108.636%0.35757%0.574SS.*EExtended strand (participates in β ladder)trans-111.3130.9175.9610000111.4G391S4-G391 PolarHBondContact N-O 3.44Å; S4-G391 WeakPolarHBondContact OG-CA 3.5Å
5S39.8Very low36.8Very low83 Ų83106 Ų10658%0.5857%0.568SS**PPolyproline II helixtrans-63.7147.9165.141.20000109.9S7S5-S7 PolarHBondContact O-N 2.83Å
6P33.3Very low36.9Very low90 Ų90101.1 Ų101.158%0.58455%0.551SS**PPolyproline II helixtrans-56.9125.9179.218-26.5000110.7
7S29.7Very low37.3Very low91 Ų91106.5 Ų106.564%0.63656%0.561SS**PPolyproline II helixtrans-67.9140.1174.750.70000110.1S5 E9S5-S7 PolarHBondContact O-N 2.83Å; S7-E9 VanDerWaalsContact C-N 3.28Å; S7-E9 PolarHBondContact O-N 3.26Å
8R29.5Very low37.7Very low255 Ų255101.1 Ų101.196%0.96253%0.533SS*.THydrogen-bonded Turntrans-75.2-1.7-173.3-87.9-175.7175.8-179-0.7115.5
9E29.3Very low37.8Very low185 Ų18596.4 Ų96.486%0.86451%0.51SS*.THydrogen-bonded Turntrans-118.62.2-167.2-80.1-175.5162.200117.4S7S7-E9 VanDerWaalsContact C-N 3.28Å; S7-E9 PolarHBondContact O-N 3.26Å
10E29.1Very low38.3Very low174 Ų17491.8 Ų91.881%0.81349%0.485SS*.SBendtrans-144.579168.8-74.6-174.3161.100110.8
11C24.6Very low39Very low93 Ų9387.5 Ų87.563%0.62846%0.462SS*.  trans-148.9108.8167.3-95.50000110.8
12P26.7Very low37.7Very low103 Ų10386 Ų8667%0.66946%0.455SS*.SBendtrans-56.6140.4144.514.3-6.2000107.3P14P12-P14 VanDerWaalsContact O-N 3.1Å
13K25.8Very low37.1Very low191 Ų19181.8 Ų81.883%0.8344%0.436SS*.  trans-42.2120.3-179.3-70.6176.7177.9176.50110.1S15K13-S15 PolarHBondContact O-N 3.11Å; K13-S15 VanDerWaalsContact O-N 3.1Å
14P33Very low36.8Very low82 Ų8281.8 Ų81.853%0.53244%0.436SS..  trans-68.6115.4-178.224.1-28.6000108.8P12 G16 Q388P12-P14 VanDerWaalsContact O-N 3.1Å; P14-G16 PolarHBondContact O-N 2.85Å; P14-Q388 VanDerWaalsContact CG-NE2 3.3Å
15S32.1Very low36.9Very low70 Ų7079.6 Ų79.649%0.4942%0.42SS..  trans-75.3-5.9168.557.70000112.7K13 R17K13-S15 PolarHBondContact O-N 3.11Å; K13-S15 VanDerWaalsContact O-N 3.1Å; S15-R17 PolarHBondContact O-N 3.37Å; S15-R17 VanDerWaalsContact O-N 3.15Å
16G37.7Very low37Very low28 Ų2875.9 Ų75.929%0.28939%0.394SS..  trans-85.981.4-174.800000113.4P14P14-G16 PolarHBondContact O-N 2.85Å
17R43.1Very low37.1Very low192 Ų19271.6 Ų71.673%0.72537%0.366SS*.  trans-69.6122.9152.8-70-178.1-179.1-174.7-0.3107.1S15S15-R17 PolarHBondContact O-N 3.37Å; S15-R17 VanDerWaalsContact O-N 3.15Å
18V44.6Very low37.6Very low9 Ų967.6 Ų67.66%0.05534%0.338CS..BIsolated β-bridgetrans-83.4126.6174.8-165.90000107.9I20 L327 V332 E385 G386 S387 L405V18-I20 HydrophobicContact CB-CD1 4.4Å; V18-I20 HydrophobicContact CG1-CD1 3.61Å; V18-I20 HydrophobicContact CG1-CG1 3.57Å; V18-L327 HydrophobicContact CG1-CD2 3.64Å; V18-V332 CarbonylContact C-O 3.38Å; V18-V332 WeakPolarHBondContact CA-O 3.46Å; V18-V332 WeakPolarHBondContact CG1-O 3.08Å; V18-E385 WeakPolarHBondContact O-CA 3.26Å; V18-G386 PolarHBondContact O-N 3.36Å; V18-S387 VanDerWaalsContact CB-O 3.23Å; V18-S387 WeakPolarHBondContact CB-O 3.19Å; V18-S387 VanDerWaalsContact CG2-O 3.29Å; V18-S387 WeakPolarHBondContact CG2-O 3.05Å; V18-S387 PolarHBondContact N-O 3.28Å; V18-L405 HydrophobicContact CG1-CD2 4.5Å; V18-L405 HydrophobicContact CG2-CD2 4.43Å
19S40.8Very low38Very low13 Ų1356 Ų569%0.09130%0.295CS..  trans-119.2122.6174.4-165.40000108.8N73 V332 G333S19-N73 PolarHBondContact OG-ND2 3.09Å; S19-V332 CarbonylContact C-O 3.58Å; S19-V332 PolarHBondContact N-O 3.5Å; S19-G333 WeakPolarHBondContact O-CA 3.48Å
20I47.5Very low38.4Very low4 Ų447.8 Ų47.82%0.02126%0.257CS..  trans-119.4105.6-157-65.5171.9000112.2V18 N73 F379 I383 L405V18-I20 HydrophobicContact CB-CD1 4.4Å; V18-I20 HydrophobicContact CG1-CD1 3.61Å; V18-I20 HydrophobicContact CG1-CG1 3.57Å; I20-N73 PolarHBondContact O-OD1 3.23Å; I20-N73 VanDerWaalsContact O-OD1 3.12Å; I20-F379 HydrophobicContact CG2-CB 4.03Å; I20-I383 WeakPolarHBondContact CB-O 3.42Å; I20-I383 HydrophobicContact CD1-CB 3.28Å; I20-I383 HydrophobicContact CD1-CD1 3.84Å; I20-I383 HydrophobicContact CD1-CG1 4.17Å; I20-I383 HydrophobicContact CD1-CG2 3.07Å; I20-I383 HydrophobicContact CG1-CB 4.47Å; I20-I383 HydrophobicContact CG1-CG2 4.45Å; I20-I383 HydrophobicContact CG2-CB 4.48Å; I20-L405 HydrophobicContact CD1-CD2 4.44Å
21M52.7Low38.7Very low1 Ų140.3 Ų40.31%0.00522%0.222CC..  trans81.1129.9148.2-57.6-146.2-85.200121N73 I323 W334 L376 F379M21-N73 PolarHBondContact O-N 2.97Å; M21-I323 HydrophobicContact CE-CD1 3.38Å; M21-I323 HydrophobicContact CE-CG1 4Å; M21-I323 HydrophobicContact CE-CG2 3.99Å; M21-I323 HydrophobicContact SD-CD1 3.47Å; M21-I323 WeakPolarHBondContact SD-CD1 3.37Å; M21-I323 HydrophobicContact SD-CG1 3.65Å; M21-I323 HydrophobicContact SD-CG2 4.26Å; M21-W334 WeakPolarHBondContact CA-O 3.21Å; M21-W334 WeakPolarHBondContact CB-O 3.44Å; M21-W334 HydrophobicContact CG-CB 3.91Å; M21-W334 HydrophobicContact CG-CE3 4.48Å; M21-W334 WeakPolarHBondContact CG-O 3.44Å; M21-W334 HydrophobicContact SD-CB 3.85Å; M21-W334 HydrophobicContact SD-CD2 3.96Å; M21-W334 HydrophobicContact SD-CE3 3.5Å; M21-W334 VanDerWaalsContact SD-CE3 3.5Å; M21-W334 HydrophobicContact SD-CG 4.15Å; M21-W334 HydrophobicContact SD-CZ3 4.38Å; M21-L376 HydrophobicContact CE-CD2 3.75Å; M21-L376 WeakPolarHBondContact CE-O 3.47Å; M21-L376 HydrophobicContact SD-CD2 3.36Å; M21-L376 WeakPolarHBondContact SD-CD2 3.19Å; M21-F379 HydrophobicContact CE-CB 3.23Å; M21-F379 HydrophobicContact CE-CD2 3.81Å; M21-F379 HydrophobicContact CE-CG 3.77Å
22A45.1Very low39.3Very low0 Ų037.7 Ų37.70%020%0.201CC..EExtended strand (participates in β ladder)trans-128.6163.6-174.800000111.1I74 W334 T335 D336A22-I74 WeakPolarHBondContact CA-O 3.33Å; A22-I74 HydrophobicContact CB-CB 3.37Å; A22-I74 HydrophobicContact CB-CG2 3.5Å; A22-I74 WeakPolarHBondContact CB-O 3.36Å; A22-W334 PolarHBondContact N-O 3.5Å; A22-T335 HydrophobicContact CB-CG2 3.33Å; A22-D336 WeakPolarHBondContact O-CB 3.22Å; A22-D336 PolarHBondContact O-N 3.14Å
23G41.5Very low39.5Very low2 Ų233.6 Ų33.62%0.02118%0.175CC..EExtended strand (participates in β ladder)trans-126.2152.114800000109.7
24S44.9Very low39.8Very low0 Ų027.4 Ų27.40%015%0.153CC..EExtended strand (participates in β ladder)trans-71.7135.7170.61740000111.9T26 W76 D336 W337 L339S24-T26 PolarHBondContact O-N 3.07Å; S24-T26 PolarHBondContact OG-N 2.96Å; S24-T26 VanDerWaalsContact OG-N 3.09Å; S24-T26 PolarHBondContact OG-OG1 3.21Å; S24-W76 VanDerWaalsContact OG-CE3 3.26Å; S24-W76 PolarHBondContact OG-O 3.02Å; S24-D336 PolarHBondContact N-O 3.2Å; S24-W337 VanDerWaalsContact CA-O 3.28Å; S24-W337 WeakPolarHBondContact CA-O 3.05Å; S24-W337 WeakPolarHBondContact CB-O 3.36Å; S24-W337 PolarHBondContact N-O 3.28Å; S24-L339 WeakPolarHBondContact O-CB 3.31Å; S24-L339 PolarHBondContact O-N 3.35Å
25L45.3Very low39.8Very low5 Ų524 Ų243%0.02613%0.132CC..THydrogen-bonded Turntrans-69.6-8.2174.1-78.2167.8000114.3G27 L28 L29 I75 W76 L116 I117 L339L25-G27 VanDerWaalsContact C-N 3.32Å; L25-G27 PolarHBondContact O-N 3.25Å; L25-G27 VanDerWaalsContact O-N 3.14Å; L25-L28 HydrophobicContact CD2-CB 4.32Å; L25-L28 HydrophobicContact CD2-CD2 4.43Å; L25-L28 PolarHBondContact O-N 2.89Å; L25-L29 HydrophobicContact CB-CD1 4.14Å; L25-L29 WeakPolarHBondContact O-CD1 3.4Å; L25-L29 VanDerWaalsContact O-CG 3.23Å; L25-L29 WeakPolarHBondContact O-CG 3.48Å; L25-L29 PolarHBondContact O-N 3.26Å; L25-I75 HydrophobicContact CD1-CD1 4.38Å; L25-I75 HydrophobicContact CD1-CG2 3.55Å; L25-I75 HydrophobicContact CG-CG2 3.82Å; L25-W76 PolarHBondContact N-O 2.95Å; L25-L116 HydrophobicContact CD1-CB 4.33Å; L25-L116 HydrophobicContact CD2-CB 4.34Å; L25-L116 HydrophobicContact CD2-CD1 4.38Å; L25-I117 HydrophobicContact CD1-CB 4.32Å; L25-I117 HydrophobicContact CD1-CD1 4.29Å; L25-I117 HydrophobicContact CD1-CG1 3.28Å; L25-L339 HydrophobicContact CD2-CD2 3.74Å
26T41.5Very low39.7Very low5 Ų528 Ų283%0.03114%0.136CC..Hα-helixtrans-48.8-48.1-171.2-42.20000113.5S24 L30 P78 C82 F84 N338S24-T26 PolarHBondContact O-N 3.07Å; S24-T26 PolarHBondContact OG-N 2.96Å; S24-T26 VanDerWaalsContact OG-N 3.09Å; S24-T26 PolarHBondContact OG-OG1 3.21Å; T26-L30 WeakPolarHBondContact O-CG 3.4Å; T26-P78 HydrophobicContact CG2-CG 3.95Å; T26-P78 WeakPolarHBondContact OG1-CG 3.22Å; T26-C82 VanDerWaalsContact CG2-SG 3.57Å; T26-F84 HydrophobicContact CG2-CB 3.59Å; T26-F84 WeakPolarHBondContact CG2-O 3.39Å; T26-N338 WeakPolarHBondContact CB-OD1 3.36Å
27G35.2Very low39.3Very low0 Ų029.6 Ų29.60%015%0.147CC..Hα-helixtrans-75.4-25.9-178.700000115.6L25 L29 L30 N338 A340L25-G27 VanDerWaalsContact C-N 3.32Å; L25-G27 PolarHBondContact O-N 3.25Å; L25-G27 VanDerWaalsContact O-N 3.14Å; G27-L29 VanDerWaalsContact C-N 3.3Å; G27-L29 PolarHBondContact O-N 3.47Å; G27-L30 PolarHBondContact O-N 2.99Å; G27-N338 PolarHBondContact N-OD1 3.24Å; G27-A340 CarbonylContact C-O 3.57Å; G27-A340 WeakPolarHBondContact CA-O 3.46Å
28L40.3Very low38.7Very low7 Ų723.9 Ų23.94%0.03714%0.136CC..Hα-helixtrans-67-36.2177.1-139.796.9000111.5L25 L30 E57 T60 I61 L116 L339 A340L25-L28 HydrophobicContact CD2-CB 4.32Å; L25-L28 HydrophobicContact CD2-CD2 4.43Å; L25-L28 PolarHBondContact O-N 2.89Å; L28-L30 VanDerWaalsContact C-N 3.29Å; L28-L30 PolarHBondContact O-N 3.22Å; L28-E57 HydrophobicContact CD2-CG 3.87Å; L28-T60 HydrophobicContact CD1-CG2 3.4Å; L28-I61 HydrophobicContact CD2-CD1 4.29Å; L28-I61 HydrophobicContact CD2-CG1 4.07Å; L28-L116 HydrophobicContact CB-CD1 4.14Å; L28-L116 HydrophobicContact CD2-CD1 3.8Å; L28-L116 HydrophobicContact CD2-CD2 4.43Å; L28-L116 HydrophobicContact CG-CD1 4.5Å; L28-L339 HydrophobicContact CD1-CB 4.34Å; L28-L339 HydrophobicContact CD1-CD2 3.87Å; L28-L339 HydrophobicContact CD1-CG 4.1Å; L28-A340 HydrophobicContact CD1-CB 3.5Å; L28-A340 VanDerWaalsContact CD1-CB 3.5Å
29L37.4Very low38Very low13 Ų1326.4 Ų26.47%0.06815%0.149CC..Hα-helixtrans-69-31.6-176.5-61.9157.4000112.4L25 G27 Q32 A33 L112 K113 L116L25-L29 HydrophobicContact CB-CD1 4.14Å; L25-L29 WeakPolarHBondContact O-CD1 3.4Å; L25-L29 VanDerWaalsContact O-CG 3.23Å; L25-L29 WeakPolarHBondContact O-CG 3.48Å; L25-L29 PolarHBondContact O-N 3.26Å; G27-L29 VanDerWaalsContact C-N 3.3Å; G27-L29 PolarHBondContact O-N 3.47Å; L29-Q32 WeakPolarHBondContact O-CB 3.48Å; L29-Q32 PolarHBondContact O-N 2.82Å; L29-A33 PolarHBondContact O-N 3.37Å; L29-L112 HydrophobicContact CB-CB 4.38Å; L29-L112 HydrophobicContact CD2-CB 3.38Å; L29-K113 HydrophobicContact CD1-CB 4.37Å; L29-K113 HydrophobicContact CD1-CD 4.05Å; L29-K113 HydrophobicContact CD1-CG 3.21Å; L29-K113 VanDerWaalsContact CD2-CA 3.42Å; L29-K113 HydrophobicContact CD2-CB 4.19Å; L29-K113 HydrophobicContact CD2-CG 3.69Å; L29-K113 HydrophobicContact CG-CG 4.07Å; L29-L116 HydrophobicContact CD2-CD1 3.38Å; L29-L116 HydrophobicContact CD2-CG 4.08Å; L29-L116 HydrophobicContact CG-CD1 3.96Å
30L37.3Very low37.5Very low11 Ų1134.5 Ų34.56%0.05819%0.186CC..Hα-helixtrans-77.9-28.5-175.5-71.8168.3000113.1T26 G27 L28 Q32 A33 V34 F84 I86 P347T26-L30 WeakPolarHBondContact O-CG 3.4Å; G27-L30 PolarHBondContact O-N 2.99Å; L28-L30 VanDerWaalsContact C-N 3.29Å; L28-L30 PolarHBondContact O-N 3.22Å; L30-Q32 VanDerWaalsContact C-N 3.26Å; L30-Q32 PolarHBondContact O-N 2.68Å; L30-A33 PolarHBondContact O-N 2.74Å; L30-V34 WeakPolarHBondContact O-CG2 3.43Å; L30-V34 PolarHBondContact O-N 3.35Å; L30-F84 HydrophobicContact CD1-CB 3.97Å; L30-F84 HydrophobicContact CD1-CD1 4.46Å; L30-F84 WeakPolarHBondContact CD1-O 3.29Å; L30-I86 HydrophobicContact CD2-CG2 3.8Å; L30-P347 HydrophobicContact CB-CG 3.39Å; L30-P347 HydrophobicContact CD1-CG 3.93Å; L30-P347 WeakPolarHBondContact CD1-O 3.41Å; L30-P347 HydrophobicContact CD2-CG 4.03Å; L30-P347 HydrophobicContact CG-CG 3.98Å
31L36.6Very low36.5Very low17 Ų1739.6 Ų39.69%0.08922%0.221CC..Hα-helixtrans-65.1-34172.5-67.3160.6000110.9S35 A340 N342 V360 I362L31-S35 PolarHBondContact O-N 2.88Å; L31-A340 HydrophobicContact CD1-CB 4.21Å; L31-N342 HydrophobicContact CD2-CB 3.97Å; L31-V360 HydrophobicContact CD1-CB 3.5Å; L31-V360 HydrophobicContact CD1-CG1 4.01Å; L31-V360 HydrophobicContact CD1-CG2 3.52Å; L31-V360 HydrophobicContact CD2-CB 4.07Å; L31-V360 HydrophobicContact CD2-CG1 4.34Å; L31-V360 HydrophobicContact CG-CB 4.43Å; L31-I362 HydrophobicContact CB-CD1 4.21Å; L31-I362 HydrophobicContact CD2-CD1 3.68Å; L31-I362 HydrophobicContact CD2-CG1 4.05Å
32Q36Very low35.3Very low38 Ų3846.4 Ų46.418%0.17826%0.256CS..Hα-helixtrans-69-42.2171.3-68.3179.9-36.900112L29 L30 S35 W36 E57 L112L29-Q32 WeakPolarHBondContact O-CB 3.48Å; L29-Q32 PolarHBondContact O-N 2.82Å; L30-Q32 VanDerWaalsContact C-N 3.26Å; L30-Q32 PolarHBondContact O-N 2.68Å; Q32-S35 WeakPolarHBondContact O-CB 3.28Å; Q32-S35 PolarHBondContact O-N 3.37Å; Q32-W36 VanDerWaalsContact O-CD1 3.27Å; Q32-W36 PolarHBondContact O-N 3.1Å; Q32-W36 VanDerWaalsContact O-N 3.07Å; Q32-E57 PolarHBondContact NE2-OE1 3.39Å; Q32-E57 PolarHBondContact NE2-OE2 2.85Å; Q32-L112 HydrophobicContact CB-CD2 4.01Å
33A31.6Very low34.5Very low17 Ų1753.8 Ų53.814%0.1429%0.291CS..Hα-helixtrans-68.2-35.5-179.600000113.4L29 L30 W36 A37 I86 L112L29-A33 PolarHBondContact O-N 3.37Å; L30-A33 PolarHBondContact O-N 2.74Å; A33-W36 PolarHBondContact O-N 2.68Å; A33-A37 WeakPolarHBondContact O-CB 3.24Å; A33-A37 PolarHBondContact O-N 3.09Å; A33-I86 HydrophobicContact CB-CD1 3.82Å; A33-L112 HydrophobicContact CB-CD1 4.32Å
34V31.8Very low34.3Very low61 Ų6158.4 Ų58.437%0.3732%0.321SS..Hα-helixtrans-69-36.2174.7174.70000111.4L30 S38 P347L30-V34 WeakPolarHBondContact O-CG2 3.43Å; L30-V34 PolarHBondContact O-N 3.35Å; V34-S38 WeakPolarHBondContact O-CB 3.41Å; V34-S38 PolarHBondContact O-N 3.47Å; V34-S38 PolarHBondContact O-OG 2.96Å; V34-P347 HydrophobicContact CG2-CB 4.24Å; V34-P347 HydrophobicContact CG2-CG 3.82Å
35S32.3Very low33.5Very low12 Ų1265.6 Ų65.68%0.08436%0.358CS..Hα-helixtrans-58.6-49170176.50000111L31 Q32 S38 D39 L53L31-S35 PolarHBondContact O-N 2.88Å; Q32-S35 WeakPolarHBondContact O-CB 3.28Å; Q32-S35 PolarHBondContact O-N 3.37Å; S35-S38 PolarHBondContact O-N 3.35Å; S35-S38 PolarHBondContact O-OG 2.88Å; S35-D39 PolarHBondContact O-N 2.96Å; S35-D39 VanDerWaalsContact O-N 3.16Å; S35-L53 WeakPolarHBondContact OG-CD1 3.36Å
36W31.6Very low33Very low153 Ų15372.8 Ų72.858%0.5839%0.392SS*.Hα-helixtrans-62.3-44.1179-84.551.4000112.9Q32 A33 S38 D39 E40 K111Q32-W36 VanDerWaalsContact O-CD1 3.27Å; Q32-W36 PolarHBondContact O-N 3.1Å; Q32-W36 VanDerWaalsContact O-N 3.07Å; A33-W36 PolarHBondContact O-N 2.68Å; W36-S38 VanDerWaalsContact C-N 3.32Å; W36-S38 PolarHBondContact O-N 3.36Å; W36-D39 PolarHBondContact O-N 3.46Å; W36-E40 PolarHBondContact O-N 3.44Å; W36-K111 HydrophobicContact CH2-CD 4.37Å
37A27.9Very low32.6Very low62 Ų6281.6 Ų81.651%0.51243%0.433SS..Hα-helixtrans-68.7-28.8178.400000113.1A33 D39A33-A37 WeakPolarHBondContact O-CB 3.24Å; A33-A37 PolarHBondContact O-N 3.09Å; A37-D39 VanDerWaalsContact C-N 3.35Å
38S29.8Very low32.3Very low71 Ų7189.7 Ų89.750%0.49747%0.47SS..Hα-helixtrans-74.4-25.1173.468.60000113.3V34 S35 W36V34-S38 WeakPolarHBondContact O-CB 3.41Å; V34-S38 PolarHBondContact O-N 3.47Å; V34-S38 PolarHBondContact O-OG 2.96Å; S35-S38 PolarHBondContact O-N 3.35Å; S35-S38 PolarHBondContact O-OG 2.88Å; W36-S38 VanDerWaalsContact C-N 3.32Å; W36-S38 PolarHBondContact O-N 3.36Å
39D31.7Very low32.1Very low62 Ų6295.5 Ų95.533%0.33250%0.495SS..Hα-helixtrans-81.8-19.2178.6-77.7-34000113.1S35 W36 A37 C41 L42S35-D39 PolarHBondContact O-N 2.96Å; S35-D39 VanDerWaalsContact O-N 3.16Å; W36-D39 PolarHBondContact O-N 3.46Å; A37-D39 VanDerWaalsContact C-N 3.35Å; D39-C41 PolarHBondContact O-N 2.99Å; D39-L42 CarbonylContact O-C 3.47Å; D39-L42 PolarHBondContact O-N 3.29Å; D39-L42 VanDerWaalsContact O-N 3.17Å
40E29.3Very low31.8Very low183 Ų183102.1 Ų102.186%0.85553%0.526SS*.THydrogen-bonded Turntrans-68.3-11.3172.2-81.3-166.6158.600113.7W36W36-E40 PolarHBondContact O-N 3.44Å
41C27.4Very low31.3Very low112 Ų112111.4 Ų111.476%0.75756%0.56SS**THydrogen-bonded Turntrans-96.2-6.9173.4-129.40000113.8D39D39-C41 PolarHBondContact O-N 2.99Å
42L27.7Very low31.1Very low144 Ų144112 Ų11275%0.75457%0.568SS**SBendtrans-151.493.1-178-73.8170.9000111.4D39D39-L42 CarbonylContact O-C 3.47Å; D39-L42 PolarHBondContact O-N 3.29Å; D39-L42 VanDerWaalsContact O-N 3.17Å
43Q26.7Very low31.3Very low155 Ų155113.4 Ų113.472%0.72458%0.576SS**  trans-99.5156.2157.5-75.1-146.3-1500111
44P38Very low32.2Very low99 Ų99115.5 Ų115.564%0.64359%0.585SS**  cis-128.2137.7-6.733.5-15.5000113.7
45L28.7Very low33.2Very low150 Ų150113.1 Ų113.179%0.78557%0.572SS**  trans-150.182.9157.5-102.3164.5000107.6
46Q34.5Very low34.2Very low157 Ų157113 Ų11373%0.73457%0.572SS**  trans-97.710.5-156.3-143.6163.8-9.500115.3
47E32.4Very low35.4Very low190 Ų190106.7 Ų106.789%0.88855%0.549SS*.SBendtrans-126-3.3-173.9-71.7-17716400115.8
48Q30.2Very low36.8Very low170 Ų170108.1 Ų108.179%0.79454%0.542SS*.SBendtrans-112.5-7.8180-79.6-176-13.400116
49K34.3Very low38.3Very low128 Ų128108.9 Ų108.956%0.55753%0.534SS*.SBendtrans-101.2-17-172-74.1-178176.1-1790116.2W51 A52K49-W51 PolarHBondContact O-N 2.77Å; K49-A52 PolarHBondContact O-N 3.01Å
50Q31.5Very low39.6Very low153 Ų153106 Ų10672%0.71552%0.519SS*.Hα-helixtrans-61-33.8177.7-155.276.818.100112D54Q50-D54 WeakPolarHBondContact O-CB 3.46Å; Q50-D54 PolarHBondContact O-N 3.01Å
51W27.2Very low41.1Very low205 Ų20597.4 Ų97.478%0.77748%0.478SS*.Hα-helixtrans-70.7-34.8-178.7136.5-91.1000114.3K49 G55K49-W51 PolarHBondContact O-N 2.77Å; W51-G55 PolarHBondContact O-N 2.82Å
52A32.7Very low42.5Very low30 Ų3095.3 Ų95.325%0.24846%0.457CS..Hα-helixtrans-74.2-41.2-177.400000111.3K49 G55 A56K49-A52 PolarHBondContact O-N 3.01Å; A52-G55 WeakPolarHBondContact O-CA 3.4Å; A52-G55 PolarHBondContact O-N 2.79Å; A52-A56 PolarHBondContact O-N 2.92Å
53L39.9Very low43.8Very low67 Ų6789.1 Ų89.135%0.35143%0.427SS..Hα-helixtrans-69.3-38.4177.5-69.4164.2000112.2S35 G55 E57S35-L53 WeakPolarHBondContact OG-CD1 3.36Å; L53-G55 PolarHBondContact O-N 2.99Å; L53-E57 WeakPolarHBondContact O-CB 3.45Å; L53-E57 PolarHBondContact O-N 2.91Å
54D50.7Low45.3Very low62 Ų6281.8 Ų81.833%0.33239%0.393SS..Hα-helixtrans-59-30.8168.8-93.3-41.2000112.2Q50 Y58 R119Q50-D54 WeakPolarHBondContact O-CB 3.46Å; Q50-D54 PolarHBondContact O-N 3.01Å; D54-Y58 WeakPolarHBondContact O-CA 3.49Å; D54-Y58 WeakPolarHBondContact O-CB 3.33Å; D54-Y58 PolarHBondContact O-N 2.6Å; D54-R119 IonicContact OD1-CZ 3.67Å; D54-R119 IonicContact OD1-NH1 3.6Å; D54-R119 PolarHBondContact OD1-NH1 3.21Å; D54-R119 IonicContact OD1-NH2 3.37Å; D54-R119 PolarHBondContact OD1-NH2 3.44Å
55G52.6Low46.2Very low10 Ų1077.6 Ų77.610%0.10337%0.366CS..Hα-helixtrans-64-63.5-17800000113.5W51 A52 L53 E57 R59W51-G55 PolarHBondContact O-N 2.82Å; A52-G55 WeakPolarHBondContact O-CA 3.4Å; A52-G55 PolarHBondContact O-N 2.79Å; L53-G55 PolarHBondContact O-N 2.99Å; G55-E57 VanDerWaalsContact C-N 3.34Å; G55-E57 PolarHBondContact O-N 3.22Å; G55-R59 VanDerWaalsContact CA-NH1 3.3Å; G55-R59 WeakPolarHBondContact O-CB 3.35Å; G55-R59 WeakPolarHBondContact O-CG 3.22Å; G55-R59 VanDerWaalsContact O-CZ 3.31Å; G55-R59 PolarHBondContact O-N 2.81Å; G55-R59 PolarHBondContact O-NE 2.96Å
56A53.8Low47.6Very low10 Ų1071.1 Ų71.18%0.08333%0.332CS..Hα-helixtrans-67.4-36.2-173.900000112.5A52 T60A52-A56 PolarHBondContact O-N 2.92Å; A56-T60 WeakPolarHBondContact O-CB 3.42Å; A56-T60 PolarHBondContact O-N 2.88Å; A56-T60 PolarHBondContact O-OG1 3.16Å
57E57.5Low48.5Very low20 Ų2065.2 Ų65.29%0.09331%0.314CS..Hα-helixtrans-67.3-53.2176.4-176-160.6132.800111.6L28 Q32 L53 G55 R59 T60 I61 L116 R119L28-E57 HydrophobicContact CD2-CG 3.87Å; Q32-E57 PolarHBondContact NE2-OE1 3.39Å; Q32-E57 PolarHBondContact NE2-OE2 2.85Å; L53-E57 WeakPolarHBondContact O-CB 3.45Å; L53-E57 PolarHBondContact O-N 2.91Å; G55-E57 VanDerWaalsContact C-N 3.34Å; G55-E57 PolarHBondContact O-N 3.22Å; E57-R59 VanDerWaalsContact C-N 3.3Å; E57-R59 PolarHBondContact O-N 2.99Å; E57-T60 WeakPolarHBondContact O-CB 2.77Å; E57-T60 PolarHBondContact O-N 2.86Å; E57-I61 HydrophobicContact CG-CD1 4.37Å; E57-I61 WeakPolarHBondContact O-CG1 3.48Å; E57-I61 PolarHBondContact O-N 2.63Å; E57-L116 HydrophobicContact CG-CD2 3.88Å; E57-L116 WeakPolarHBondContact OE1-CD2 3.38Å; E57-R119 IonicContact OE1-CZ 3.5Å; E57-R119 IonicContact OE1-NE 2.82Å; E57-R119 IonicContact OE1-NH1 2.99Å; E57-R119 PolarHBondContact OE1-NH1 3.16Å; E57-R119 IonicContact OE2-NH1 3.77Å
58Y56.5Low50.2Low92 Ų9261.9 Ų61.936%0.36131%0.307SS..Hα-helixtrans-59.1-43.7175.8-179.4-96.3000110.7D54 T60 I61 Q62 L123D54-Y58 WeakPolarHBondContact O-CA 3.49Å; D54-Y58 WeakPolarHBondContact O-CB 3.33Å; D54-Y58 PolarHBondContact O-N 2.6Å; Y58-T60 VanDerWaalsContact C-N 3.26Å; Y58-T60 PolarHBondContact O-N 2.91Å; Y58-I61 PolarHBondContact O-N 2.85Å; Y58-Q62 HydrophobicContact CE1-CB 4.43Å; Y58-Q62 VanDerWaalsContact CE1-OE1 3.3Å; Y58-Q62 WeakPolarHBondContact O-CA 3.43Å; Y58-Q62 WeakPolarHBondContact O-CB 3.48Å; Y58-Q62 PolarHBondContact O-N 2.99Å; Y58-L123 HydrophobicContact CD2-CD1 4.19Å; Y58-L123 HydrophobicContact CE2-CD1 3.89Å; Y58-L123 HydrophobicContact CE2-CD2 3.96Å; Y58-L123 HydrophobicContact CE2-CG 4.42Å
59R60.5Low52.5Low88 Ų8854.2 Ų54.233%0.33227%0.273SS..Hα-helixtrans-61.8-34.8176.5-73.5-178.9-62.6-10210.4112G55 E57 A63 D365 F367G55-R59 VanDerWaalsContact CA-NH1 3.3Å; G55-R59 WeakPolarHBondContact O-CB 3.35Å; G55-R59 WeakPolarHBondContact O-CG 3.22Å; G55-R59 VanDerWaalsContact O-CZ 3.31Å; G55-R59 PolarHBondContact O-N 2.81Å; G55-R59 PolarHBondContact O-NE 2.96Å; E57-R59 VanDerWaalsContact C-N 3.3Å; E57-R59 PolarHBondContact O-N 2.99Å; R59-A63 WeakPolarHBondContact O-CB 3.3Å; R59-A63 PolarHBondContact O-N 3.28Å; R59-D365 IonicContact NH2-OD1 3.45Å; R59-D365 PolarHBondContact NH2-OD1 3.28Å; R59-D365 IonicContact NH2-OD2 3.37Å; R59-F367 HydrophobicContact CB-CD1 4.45Å; R59-F367 HydrophobicContact CB-CE1 3.46Å; R59-F367 VanDerWaalsContact CB-CE1 3.46Å; R59-F367 HydrophobicContact CB-CZ 3.81Å; R59-F367 HydrophobicContact CG-CE1 4.34Å
60T58.7Low54.8Low1 Ų148.7 Ų48.71%0.00625%0.25CC..Hα-helixtrans-69.3-50.9176-63.20000111.6L28 A56 E57 Y58 Q62 A63 N64 I358L28-T60 HydrophobicContact CD1-CG2 3.4Å; A56-T60 WeakPolarHBondContact O-CB 3.42Å; A56-T60 PolarHBondContact O-N 2.88Å; A56-T60 PolarHBondContact O-OG1 3.16Å; E57-T60 WeakPolarHBondContact O-CB 2.77Å; E57-T60 PolarHBondContact O-N 2.86Å; Y58-T60 VanDerWaalsContact C-N 3.26Å; Y58-T60 PolarHBondContact O-N 2.91Å; T60-Q62 VanDerWaalsContact C-N 3.28Å; T60-Q62 PolarHBondContact O-N 3.21Å; T60-A63 PolarHBondContact O-N 3.26Å; T60-N64 PolarHBondContact O-N 3.19Å; T60-N64 VanDerWaalsContact O-N 3.09Å; T60-N64 PolarHBondContact O-ND2 3.16Å; T60-I358 HydrophobicContact CG2-CD1 3.55Å; T60-I358 HydrophobicContact CG2-CG2 4.27Å
61I62.6Low57.4Low2 Ų241.8 Ų41.81%0.0122%0.219CC..Hα-helixtrans-60.9-41.8176.2-61.9173.7000110.1L28 E57 Y58 A63 N64 C65 L116 R119 A120 L123L28-I61 HydrophobicContact CD2-CD1 4.29Å; L28-I61 HydrophobicContact CD2-CG1 4.07Å; E57-I61 HydrophobicContact CG-CD1 4.37Å; E57-I61 WeakPolarHBondContact O-CG1 3.48Å; E57-I61 PolarHBondContact O-N 2.63Å; Y58-I61 PolarHBondContact O-N 2.85Å; I61-A63 PolarHBondContact O-N 3.19Å; I61-N64 PolarHBondContact O-N 3.2Å; I61-C65 HydrophobicContact CG2-CB 4.47Å; I61-C65 WeakPolarHBondContact O-CB 3.28Å; I61-C65 PolarHBondContact O-N 3.48Å; I61-L116 HydrophobicContact CD1-CD2 4.12Å; I61-R119 HydrophobicContact CD1-CB 4.1Å; I61-A120 VanDerWaalsContact CG2-CA 3.47Å; I61-A120 HydrophobicContact CG2-CB 3.75Å; I61-L123 HydrophobicContact CB-CD1 4.16Å; I61-L123 HydrophobicContact CG2-CD1 3.57Å
62Q55.8Low60.2Low68 Ų6832.3 Ų32.332%0.31818%0.184SC..Hα-helixtrans-61-44.8177-173-177.65.300111.5Y58 T60 N64 T66Y58-Q62 HydrophobicContact CE1-CB 4.43Å; Y58-Q62 VanDerWaalsContact CE1-OE1 3.3Å; Y58-Q62 WeakPolarHBondContact O-CA 3.43Å; Y58-Q62 WeakPolarHBondContact O-CB 3.48Å; Y58-Q62 PolarHBondContact O-N 2.99Å; T60-Q62 VanDerWaalsContact C-N 3.28Å; T60-Q62 PolarHBondContact O-N 3.21Å; Q62-N64 PolarHBondContact O-N 2.75Å; Q62-T66 HydrophobicContact CB-CG2 4.41Å; Q62-T66 HydrophobicContact CG-CG2 3.8Å; Q62-T66 PolarHBondContact O-N 2.8Å; Q62-T66 PolarHBondContact O-OG1 3.47Å
63A54.3Low62.7Low14 Ų1431 Ų3112%0.11617%0.173CC..Hα-helixtrans-61.9-32.6177.300000112.3R59 T60 I61 G69 I70 F373R59-A63 WeakPolarHBondContact O-CB 3.3Å; R59-A63 PolarHBondContact O-N 3.28Å; T60-A63 PolarHBondContact O-N 3.26Å; I61-A63 PolarHBondContact O-N 3.19Å; A63-G69 CarbonylContact O-C 3.49Å; A63-G69 WeakPolarHBondContact O-CA 3.31Å; A63-I70 PolarHBondContact O-N 2.75Å; A63-F373 HydrophobicContact CB-CE2 4.13Å; A63-F373 HydrophobicContact CB-CZ 4.04Å; A63-F373 WeakPolarHBondContact O-CZ 3.17Å
64N59.8Low65Low1 Ų127.9 Ų27.91%0.00516%0.156CC..Hα-helixtrans-86.5-45-178.4-70.4-46.4000113.6T60 I61 Q62 I70 G71 Y72 L339 I358 F373T60-N64 PolarHBondContact O-N 3.19Å; T60-N64 VanDerWaalsContact O-N 3.09Å; T60-N64 PolarHBondContact O-ND2 3.16Å; I61-N64 PolarHBondContact O-N 3.2Å; Q62-N64 PolarHBondContact O-N 2.75Å; N64-I70 CarbonylContact O-C 3.57Å; N64-G71 PolarHBondContact O-N 2.66Å; N64-Y72 HydrophobicContact CB-CD2 4.05Å; N64-Y72 HydrophobicContact CB-CE2 4.42Å; N64-Y72 HydrophobicContact CB-CG 4.4Å; N64-Y72 PolarHBondContact O-N 3.06Å; N64-L339 HydrophobicContact CB-CD1 4.42Å; N64-L339 VanDerWaalsContact ND2-CD1 3.31Å; N64-L339 WeakPolarHBondContact ND2-CD1 3.44Å; N64-I358 WeakPolarHBondContact ND2-CD1 3.49Å; N64-F373 WeakPolarHBondContact OD1-CE2 3.19Å
65C56.7Low66.8Low12 Ų1225.4 Ų25.48%0.08114%0.142CC..Hα-helixtrans-102.9-19.6-162.7-60.20000115I61 L123 A124I61-C65 HydrophobicContact CG2-CB 4.47Å; I61-C65 WeakPolarHBondContact O-CB 3.28Å; I61-C65 PolarHBondContact O-N 3.48Å; C65-L123 HydrophobicContact CB-CB 4.44Å; C65-A124 HydrophobicContact CB-CB 4.42Å; C65-A124 WeakPolarHBondContact O-CA 3.04Å
66T57.2Low68.7Low13 Ų1324.9 Ų24.98%0.0814%0.138CC..SBendtrans-84.9163.5-17464.10000114.1Q62 T68 G69 L123Q62-T66 HydrophobicContact CB-CG2 4.41Å; Q62-T66 HydrophobicContact CG-CG2 3.8Å; Q62-T66 PolarHBondContact O-N 2.8Å; Q62-T66 PolarHBondContact O-OG1 3.47Å; T66-T68 PolarHBondContact O-N 2.93Å; T66-T68 PolarHBondContact OG1-OG1 2.95Å; T66-G69 CarbonylContact O-C 3.56Å; T66-G69 WeakPolarHBondContact O-CA 3.41Å; T66-G69 PolarHBondContact O-N 3.46Å; T66-G69 PolarHBondContact OG1-N 2.77Å; T66-G69 VanDerWaalsContact OG1-N 3.09Å; T66-L123 HydrophobicContact CG2-CB 3.89Å; T66-L123 HydrophobicContact CG2-CD2 4.04Å; T66-L123 HydrophobicContact CG2-CG 4.46Å
67G53.7Low70.8Confident33 Ų3324.5 Ų24.534%0.3413%0.134SC..THydrogen-bonded Turntrans-61.1-24.717000000113.9K381G67-K381 PolarHBondContact O-NZ 3.29Å
68T67.5Low72.7Confident121 Ų12123.8 Ų23.874%0.74213%0.131SC*.THydrogen-bonded Turntrans-81-16.2170.146.30000113.6T66T66-T68 PolarHBondContact O-N 2.93Å; T66-T68 PolarHBondContact OG1-OG1 2.95Å
69G79.9Confident74.7Confident9 Ų919.5 Ų19.59%0.09311%0.114CC..THydrogen-bonded Turntrans-93.7-150.1176.100000113.4A63 T66 K381A63-G69 CarbonylContact O-C 3.49Å; A63-G69 WeakPolarHBondContact O-CA 3.31Å; T66-G69 CarbonylContact O-C 3.56Å; T66-G69 WeakPolarHBondContact O-CA 3.41Å; T66-G69 PolarHBondContact O-N 3.46Å; T66-G69 PolarHBondContact OG1-N 2.77Å; T66-G69 VanDerWaalsContact OG1-N 3.09Å; G69-K381 PolarHBondContact O-NZ 2.92Å
70I82.6Confident76.4Confident12 Ų1215.4 Ų15.46%0.06210%0.1CC..THydrogen-bonded Turntrans-97.20.7178.861.1174.3000114.5A63 N64 Y72 F373 S380 K381A63-I70 PolarHBondContact O-N 2.75Å; N64-I70 CarbonylContact O-C 3.57Å; I70-Y72 HydrophobicContact CD1-CD1 3.93Å; I70-Y72 HydrophobicContact CD1-CE1 3.24Å; I70-Y72 HydrophobicContact CG1-CD1 3.88Å; I70-Y72 HydrophobicContact CG1-CE1 3.73Å; I70-F373 HydrophobicContact CB-CZ 4.32Å; I70-F373 HydrophobicContact CD1-CD1 4.43Å; I70-F373 HydrophobicContact CD1-CD2 3.89Å; I70-F373 HydrophobicContact CD1-CE1 4.1Å; I70-F373 HydrophobicContact CD1-CE2 3.59Å; I70-F373 HydrophobicContact CD1-CG 4.31Å; I70-F373 HydrophobicContact CD1-CZ 3.68Å; I70-F373 HydrophobicContact CG1-CE1 4.4Å; I70-F373 HydrophobicContact CG1-CE2 4.06Å; I70-F373 HydrophobicContact CG1-CZ 3.8Å; I70-F373 HydrophobicContact CG2-CD1 4.33Å; I70-F373 HydrophobicContact CG2-CE1 3.45Å; I70-F373 VanDerWaalsContact CG2-CE1 3.45Å; I70-F373 HydrophobicContact CG2-CZ 3.63Å; I70-S380 CarbonylContact O-C 3.44Å; I70-S380 VanDerWaalsContact O-CB 3.3Å; I70-S380 WeakPolarHBondContact O-CB 3.48Å; I70-S380 PolarHBondContact O-OG 3.39Å; I70-S380 VanDerWaalsContact O-OG 3.09Å; I70-K381 WeakPolarHBondContact O-CA 3.35Å; I70-K381 PolarHBondContact O-N 3.19Å
71G84.9Confident78.2Confident7 Ų715.5 Ų15.57%0.07210%0.1CC..  trans67.340.1165.600000115.7N64 R126N64-G71 PolarHBondContact O-N 2.66Å; G71-R126 PolarHBondContact O-NH1 2.91Å; G71-R126 VanDerWaalsContact O-NH1 3.12Å
72Y85.6Confident79.8Confident7 Ų715.4 Ų15.43%0.02710%0.1CC..  trans-54.1139.1171.9-78.68.2000111.7N64 I70 L339 L376N64-Y72 HydrophobicContact CB-CD2 4.05Å; N64-Y72 HydrophobicContact CB-CE2 4.42Å; N64-Y72 HydrophobicContact CB-CG 4.4Å; N64-Y72 PolarHBondContact O-N 3.06Å; I70-Y72 HydrophobicContact CD1-CD1 3.93Å; I70-Y72 HydrophobicContact CD1-CE1 3.24Å; I70-Y72 HydrophobicContact CG1-CD1 3.88Å; I70-Y72 HydrophobicContact CG1-CE1 3.73Å; Y72-L339 HydrophobicContact CD2-CD1 4.11Å; Y72-L339 HydrophobicContact CE2-CD1 3.7Å; Y72-L376 WeakPolarHBondContact OH-CD1 3.44Å
73N86.1Confident81.5Confident3 Ų312.4 Ų12.42%0.0169%0.086CC..  trans-130.610.5-178.580.2-39.7000113.4S19 I20 M21 R126 V128 S129S19-N73 PolarHBondContact OG-ND2 3.09Å; I20-N73 PolarHBondContact O-OD1 3.23Å; I20-N73 VanDerWaalsContact O-OD1 3.12Å; M21-N73 PolarHBondContact O-N 2.97Å; N73-R126 HydrophobicContact CB-CB 4.46Å; N73-V128 CarbonylContact O-C 3.5Å; N73-V128 VanDerWaalsContact O-CA 3.28Å; N73-V128 WeakPolarHBondContact O-CA 3.43Å; N73-S129 PolarHBondContact O-N 3.19Å
74I87.8Confident83.3Confident1 Ų111.8 Ų11.81%0.0058%0.08CC..EExtended strand (participates in β ladder)trans-130.2145.5172.1-60.1173.6000107.3A22 S129 F293A22-I74 WeakPolarHBondContact CA-O 3.33Å; A22-I74 HydrophobicContact CB-CB 3.37Å; A22-I74 HydrophobicContact CB-CG2 3.5Å; A22-I74 WeakPolarHBondContact CB-O 3.36Å; I74-S129 CarbonylContact C-O 3.37Å; I74-S129 VanDerWaalsContact CA-O 3.24Å; I74-S129 WeakPolarHBondContact CA-O 3.44Å; I74-F293 HydrophobicContact CD1-CE2 3.6Å; I74-F293 HydrophobicContact CD1-CZ 3.63Å; I74-F293 HydrophobicContact CG2-CZ 4.43Å
75I89.4Confident84.7Confident9 Ų912.3 Ų12.35%0.0468%0.084CC..EExtended strand (participates in β ladder)trans-131.1124.2167.9-63.9172.4000107.4L25 V77 I117 A120 V128 S129 L130 L131L25-I75 HydrophobicContact CD1-CD1 4.38Å; L25-I75 HydrophobicContact CD1-CG2 3.55Å; L25-I75 HydrophobicContact CG-CG2 3.82Å; I75-V77 HydrophobicContact CG2-CG2 4.01Å; I75-I117 HydrophobicContact CD1-CG2 4.5Å; I75-I117 HydrophobicContact CG2-CG1 4.45Å; I75-A120 HydrophobicContact CD1-CB 3.77Å; I75-V128 HydrophobicContact CB-CG1 4.48Å; I75-V128 HydrophobicContact CD1-CG1 3.83Å; I75-V128 HydrophobicContact CG1-CG1 3.76Å; I75-S129 PolarHBondContact N-O 3.39Å; I75-L130 HydrophobicContact CB-CD2 3.8Å; I75-L130 HydrophobicContact CD1-CD2 4.25Å; I75-L130 HydrophobicContact CG1-CD2 4.45Å; I75-L130 HydrophobicContact CG2-CD2 4.39Å; I75-L130 WeakPolarHBondContact O-CA 3.44Å; I75-L131 PolarHBondContact O-N 3.31Å
76W92.5Very high86.2Confident0 Ų015.6 Ų15.60%010%0.1CC..EExtended strand (participates in β ladder)trans-90.1131173.4-17089.2000110.4S24 L25 P78 L131 S133 W135 T335 W337S24-W76 VanDerWaalsContact OG-CE3 3.26Å; S24-W76 PolarHBondContact OG-O 3.02Å; L25-W76 PolarHBondContact N-O 2.95Å; W76-P78 HydrophobicContact CE3-CG 4.33Å; W76-P78 HydrophobicContact CZ3-CG 4Å; W76-L131 CarbonylContact C-O 3.14Å; W76-L131 WeakPolarHBondContact CA-O 3.28Å; W76-S133 VanDerWaalsContact CZ2-CB 3.42Å; W76-S133 WeakPolarHBondContact CZ2-OG 3.33Å; W76-S133 PolarHBondContact NE1-OG 2.81Å; W76-W135 HydrophobicContact CE3-CH2 4.41Å; W76-W135 AromaticContact CH2-CH2 2.91Å; W76-W135 HydrophobicContact CH2-CH2 2.91Å; W76-W135 AromaticContact CH2-CZ2 3.11Å; W76-W135 HydrophobicContact CH2-CZ2 3.11Å; W76-W135 AromaticContact CH2-CZ3 3.8Å; W76-W135 HydrophobicContact CH2-CZ3 3.8Å; W76-W135 AromaticContact CZ2-CH2 3.94Å; W76-W135 HydrophobicContact CZ2-CH2 3.94Å; W76-W135 HydrophobicContact CZ2-CZ2 4.22Å; W76-W135 HydrophobicContact CZ2-CZ3 4.49Å; W76-W135 AromaticContact CZ3-CH2 3.2Å; W76-W135 HydrophobicContact CZ3-CH2 3.2Å; W76-W135 AromaticContact CZ3-CZ2 3.59Å; W76-W135 HydrophobicContact CZ3-CZ2 3.59Å; W76-W135 HydrophobicContact CZ3-CZ3 4.27Å; W76-T335 HydrophobicContact CB-CG2 3.97Å; W76-W337 HydrophobicContact CD2-CZ3 4.26Å; W76-W337 HydrophobicContact CE3-CE3 4.31Å; W76-W337 AromaticContact CE3-CZ3 3.85Å; W76-W337 HydrophobicContact CE3-CZ3 3.85Å; W76-W337 HydrophobicContact CH2-CE3 4.13Å; W76-W337 AromaticContact CH2-CH2 3.07Å; W76-W337 HydrophobicContact CH2-CH2 3.07Å; W76-W337 HydrophobicContact CH2-CZ2 4.19Å; W76-W337 AromaticContact CH2-CZ3 2.99Å; W76-W337 HydrophobicContact CH2-CZ3 2.99Å; W76-W337 AromaticContact CZ2-CH2 3.91Å; W76-W337 HydrophobicContact CZ2-CH2 3.91Å; W76-W337 AromaticContact CZ2-CZ3 3.6Å; W76-W337 HydrophobicContact CZ2-CZ3 3.6Å; W76-W337 AromaticContact CZ3-CE3 3.88Å; W76-W337 HydrophobicContact CZ3-CE3 3.88Å; W76-W337 AromaticContact CZ3-CH2 3.46Å; W76-W337 HydrophobicContact CZ3-CH2 3.46Å; W76-W337 VanDerWaalsContact CZ3-CH2 3.46Å; W76-W337 HydrophobicContact CZ3-CZ2 4.32Å; W76-W337 AromaticContact CZ3-CZ3 3.15Å; W76-W337 HydrophobicContact CZ3-CZ3 3.15Å
77V96.2Very high87.9Confident2 Ų219.9 Ų19.91%0.01212%0.115CC..EExtended strand (participates in β ladder)trans-124.1113.7-170.7-173.80000109.6I75 M79 I117 L131 A132 S133 Y176 F183I75-V77 HydrophobicContact CG2-CG2 4.01Å; V77-M79 PolarHBondContact O-N 3.47Å; V77-I117 HydrophobicContact CG1-CD1 4.36Å; V77-I117 HydrophobicContact CG2-CD1 3.78Å; V77-L131 PolarHBondContact N-O 3.27Å; V77-A132 VanDerWaalsContact O-CA 3.24Å; V77-A132 WeakPolarHBondContact O-CA 3.18Å; V77-A132 WeakPolarHBondContact O-CB 3.46Å; V77-S133 PolarHBondContact O-N 3.45Å; V77-Y176 HydrophobicContact CG1-CE1 4.07Å; V77-F183 HydrophobicContact CB-CE1 3.99Å; V77-F183 HydrophobicContact CB-CZ 4.23Å; V77-F183 HydrophobicContact CG1-CZ 4.38Å; V77-F183 HydrophobicContact CG2-CE1 4.07Å; V77-F183 HydrophobicContact CG2-CZ 4.35Å
78P97.5Very high89.9Confident4 Ų422.4 Ų22.43%0.02612%0.124CC..EExtended strand (participates in β ladder)trans-54.2136.6171.9-26.429.8000113.2T26 W76 A80 K113 W135T26-P78 HydrophobicContact CG2-CG 3.95Å; T26-P78 WeakPolarHBondContact OG1-CG 3.22Å; W76-P78 HydrophobicContact CE3-CG 4.33Å; W76-P78 HydrophobicContact CZ3-CG 4Å; P78-A80 PolarHBondContact O-N 3.28Å; P78-K113 PolarHBondContact O-NZ 3.15Å; P78-W135 HydrophobicContact CB-CE3 4.44Å; P78-W135 HydrophobicContact CB-CH2 3.39Å; P78-W135 HydrophobicContact CB-CZ3 3.26Å; P78-W135 HydrophobicContact CG-CH2 3.63Å; P78-W135 HydrophobicContact CG-CZ3 4.05Å
79M98.5Very high91.3Very high2 Ų217.2 Ų17.21%0.019%0.091CC..EExtended strand (participates in β ladder)trans-88.5100.8164.1-59.3175.265.300109.2V77 Y91 A132 S133 P134 Y168 I169 F172V77-M79 PolarHBondContact O-N 3.47Å; M79-Y91 HydrophobicContact CB-CE2 4.3Å; M79-A132 HydrophobicContact CG-CB 3.92Å; M79-A132 HydrophobicContact SD-CB 4.25Å; M79-S133 PolarHBondContact N-O 3.07Å; M79-P134 HydrophobicContact CB-CB 3.97Å; M79-P134 HydrophobicContact SD-CB 4.08Å; M79-P134 HydrophobicContact SD-CG 4.07Å; M79-Y168 HydrophobicContact CE-CD1 4.42Å; M79-Y168 HydrophobicContact CE-CE1 4.36Å; M79-I169 HydrophobicContact CE-CB 4.14Å; M79-I169 HydrophobicContact CE-CG1 3.8Å; M79-I169 HydrophobicContact CE-CG2 4.18Å; M79-F172 HydrophobicContact CE-CB 3.62Å; M79-F172 HydrophobicContact CE-CD1 3.51Å; M79-F172 HydrophobicContact CE-CD2 4.35Å; M79-F172 HydrophobicContact CE-CE1 4.25Å; M79-F172 HydrophobicContact CE-CG 3.56Å; M79-F172 HydrophobicContact CG-CD1 4.02Å; M79-F172 HydrophobicContact CG-CD2 4.24Å; M79-F172 HydrophobicContact CG-CE1 3.83Å; M79-F172 HydrophobicContact CG-CE2 4.02Å; M79-F172 HydrophobicContact CG-CG 4.21Å; M79-F172 HydrophobicContact CG-CZ 3.8Å; M79-F172 HydrophobicContact SD-CD1 4.02Å; M79-F172 HydrophobicContact SD-CE1 4.18Å; M79-F172 HydrophobicContact SD-CG 4.46Å
80A97.8Very high92.2Very high3 Ų317.5 Ų17.53%0.0259%0.091CC..SBendtrans67.2-142-171.200000112.8P78 Y89 Y91P78-A80 PolarHBondContact O-N 3.28Å; A80-Y89 HydrophobicContact CB-CD2 3.92Å; A80-Y89 HydrophobicContact CB-CE2 3.73Å; A80-Y89 WeakPolarHBondContact CB-O 3.42Å; A80-Y91 HydrophobicContact CB-CD1 4Å; A80-Y91 HydrophobicContact CB-CD2 4.38Å; A80-Y91 HydrophobicContact CB-CE1 3.73Å; A80-Y91 HydrophobicContact CB-CE2 4.12Å; A80-Y91 HydrophobicContact CB-CG 4.32Å; A80-Y91 PolarHBondContact N-OH 2.99Å
81S96.6Very high92.9Very high3 Ų317.1 Ų17.12%0.0219%0.088CC..  trans-85.4153-173.966.50000114.4S85 Y89 Q203S81-S85 WeakPolarHBondContact CA-OG 3.3Å; S81-Y89 WeakPolarHBondContact CB-O 3.39Å; S81-Y89 PolarHBondContact N-O 3.33Å; S81-Y89 PolarHBondContact OG-N 3.43Å; S81-Y89 PolarHBondContact OG-O 3.09Å; S81-Q203 VanDerWaalsContact CB-NE2 3.3Å; S81-Q203 PolarHBondContact OG-NE2 3.49Å
82C95.1Very high93.5Very high0 Ų016.8 Ų16.80%09%0.085CC..  trans-135.4-166.3169.466.70000111.4T26 F84 S85 W135 Q203 W349T26-C82 VanDerWaalsContact CG2-SG 3.57Å; C82-F84 PolarHBondContact SG-N 3.18Å; C82-S85 PolarHBondContact N-OG 3.01Å; C82-S85 VanDerWaalsContact O-CB 3.26Å; C82-S85 WeakPolarHBondContact O-CB 3.12Å; C82-S85 PolarHBondContact O-N 2.98Å; C82-S85 PolarHBondContact O-OG 3.24Å; C82-W135 HydrophobicContact CB-CD2 3.36Å; C82-W135 HydrophobicContact CB-CE3 3.71Å; C82-W135 HydrophobicContact CB-CG 3.91Å; C82-W135 HydrophobicContact CB-CH2 3.56Å; C82-W135 HydrophobicContact CB-CZ2 3.13Å; C82-W135 HydrophobicContact CB-CZ3 3.87Å; C82-Q203 VanDerWaalsContact C-CD 3.5Å; C82-Q203 VanDerWaalsContact C-NE2 3.32Å; C82-Q203 VanDerWaalsContact C-OE1 3.31Å; C82-Q203 PolarHBondContact O-NE2 3.42Å; C82-Q203 PolarHBondContact O-OE1 2.67Å; C82-W349 PolarHBondContact O-NE1 2.99Å
83D91.2Very high93.9Very high4 Ų420.6 Ų20.62%0.02111%0.106CC..THydrogen-bonded Turntrans-63.9-39.1174.666.4-37.9000112.3S85 F202 N348 W349 V350 N352D83-S85 PolarHBondContact O-N 2.93Å; D83-F202 HydrophobicContact CB-CB 3.86Å; D83-F202 HydrophobicContact CB-CD1 3.99Å; D83-F202 HydrophobicContact CB-CD2 3.78Å; D83-F202 HydrophobicContact CB-CE1 4.45Å; D83-F202 HydrophobicContact CB-CE2 4.24Å; D83-F202 HydrophobicContact CB-CG 3.62Å; D83-N348 VanDerWaalsContact C-ND2 3.28Å; D83-N348 WeakPolarHBondContact O-CA 3.43Å; D83-N348 PolarHBondContact O-ND2 3.34Å; D83-N348 PolarHBondContact O-OD1 3.31Å; D83-N348 PolarHBondContact OD2-ND2 2.99Å; D83-W349 VanDerWaalsContact O-CD1 3.25Å; D83-W349 PolarHBondContact O-N 3.42Å; D83-W349 VanDerWaalsContact O-N 3.14Å; D83-V350 HydrophobicContact CB-CG2 3.9Å; D83-N352 PolarHBondContact OD2-ND2 2.83Å
84F91.8Very high94.1Very high1 Ų123.1 Ų23.10%0.00412%0.122CC..THydrogen-bonded Turntrans-7743.2167.5-71.1-87000112.2T26 L30 C82 W337 N338 L341 N348 N352 V354T26-F84 HydrophobicContact CG2-CB 3.59Å; T26-F84 WeakPolarHBondContact CG2-O 3.39Å; L30-F84 HydrophobicContact CD1-CB 3.97Å; L30-F84 HydrophobicContact CD1-CD1 4.46Å; L30-F84 WeakPolarHBondContact CD1-O 3.29Å; C82-F84 PolarHBondContact SG-N 3.18Å; F84-W337 AromaticContact CD2-NE1 3.5Å; F84-W337 AromaticContact CE2-CD1 3.97Å; F84-W337 AromaticContact CE2-NE1 3.5Å; F84-N338 WeakPolarHBondContact CD1-ND2 3.27Å; F84-N338 WeakPolarHBondContact CD2-ND2 3.46Å; F84-N338 VanDerWaalsContact CE1-ND2 3.29Å; F84-N338 WeakPolarHBondContact CE1-ND2 3.29Å; F84-N338 WeakPolarHBondContact CE2-ND2 3.48Å; F84-N338 WeakPolarHBondContact CG-ND2 3.37Å; F84-N338 VanDerWaalsContact CZ-ND2 3.35Å; F84-N338 WeakPolarHBondContact CZ-ND2 3.39Å; F84-L341 HydrophobicContact CD1-CD2 3.76Å; F84-L341 HydrophobicContact CE1-CD1 4.06Å; F84-L341 HydrophobicContact CE1-CD2 3.69Å; F84-N348 HydrophobicContact CD1-CB 4.2Å; F84-N348 WeakPolarHBondContact CD2-ND2 3.48Å; F84-N348 HydrophobicContact CE1-CB 4.17Å; F84-N348 WeakPolarHBondContact CE2-ND2 3.28Å; F84-N348 WeakPolarHBondContact CZ-ND2 3.33Å; F84-N352 VanDerWaalsContact CZ-O 3.31Å; F84-N352 WeakPolarHBondContact CZ-O 3.46Å; F84-V354 HydrophobicContact CE1-CG2 4.13Å; F84-V354 HydrophobicContact CE2-CG2 4.16Å; F84-V354 HydrophobicContact CZ-CB 4.33Å; F84-V354 HydrophobicContact CZ-CG1 4.19Å; F84-V354 HydrophobicContact CZ-CG2 3.43Å; F84-V354 VanDerWaalsContact CZ-CG2 3.43Å
85S89.9Confident94Very high12 Ų1227.8 Ų27.88%0.08415%0.152CC..SBendtrans-120.7155.8164.3-59.30000108.7S81 C82 D83 R87 W349S81-S85 WeakPolarHBondContact CA-OG 3.3Å; C82-S85 PolarHBondContact N-OG 3.01Å; C82-S85 VanDerWaalsContact O-CB 3.26Å; C82-S85 WeakPolarHBondContact O-CB 3.12Å; C82-S85 PolarHBondContact O-N 2.98Å; C82-S85 PolarHBondContact O-OG 3.24Å; D83-S85 PolarHBondContact O-N 2.93Å; S85-R87 WeakPolarHBondContact CB-O 3.15Å; S85-W349 VanDerWaalsContact O-CB 3.25Å; S85-W349 WeakPolarHBondContact O-CB 3.39Å; S85-W349 VanDerWaalsContact O-CD1 3.27Å; S85-W349 PolarHBondContact O-N 3.39Å; S85-W349 VanDerWaalsContact O-N 3.14Å
86I88.2Confident93.5Very high82 Ų8233.3 Ų33.342%0.42118%0.182SC..SBendtrans-88.5-15.2173.758.5172.5000113.2L30 A33 P347L30-I86 HydrophobicContact CD2-CG2 3.8Å; A33-I86 HydrophobicContact CB-CD1 3.82Å; I86-P347 HydrophobicContact CG2-CB 4.07Å; I86-P347 HydrophobicContact CG2-CG 3.98Å
87R92.9Very high93.4Very high103 Ų10334.1 Ų34.139%0.38919%0.186SC..SBendtrans-139155.6173.772.5178.9-177.490.48.5110.3S85 Y89 E108S85-R87 WeakPolarHBondContact CB-O 3.15Å; R87-Y89 HydrophobicContact CG-CD1 3.94Å; R87-E108 IonicContact CZ-OE1 3.66Å; R87-E108 VanDerWaalsContact CZ-OE1 3.25Å; R87-E108 IonicContact CZ-OE2 3.47Å; R87-E108 IonicContact NE-OE1 2.7Å; R87-E108 PolarHBondContact NE-OE1 3.41Å; R87-E108 IonicContact NE-OE2 2.93Å; R87-E108 IonicContact NH2-OE1 2.91Å; R87-E108 PolarHBondContact NH2-OE1 2.84Å; R87-E108 VanDerWaalsContact NH2-OE1 3.11Å; R87-E108 IonicContact NH2-OE2 3.86Å; R87-E108 PolarHBondContact NH2-OE2 2.89Å
88T95.8Very high93.3Very high86 Ų8636 Ų3653%0.52819%0.194SC..  trans-91.3130.8174.955.30000109.9W349T88-W349 HydrophobicContact CG2-CD2 4Å; T88-W349 HydrophobicContact CG2-CE3 4.4Å; T88-W349 HydrophobicContact CG2-CH2 4.08Å; T88-W349 HydrophobicContact CG2-CZ2 3.62Å; T88-W349 HydrophobicContact CG2-CZ3 4.44Å
89Y97.1Very high93.2Very high12 Ų1241.6 Ų41.65%0.04722%0.22CC..  trans-160.5156.6179.270-89.8000112.3A80 S81 R87 Y91 P106 E108 D109A80-Y89 HydrophobicContact CB-CD2 3.92Å; A80-Y89 HydrophobicContact CB-CE2 3.73Å; A80-Y89 WeakPolarHBondContact CB-O 3.42Å; S81-Y89 WeakPolarHBondContact CB-O 3.39Å; S81-Y89 PolarHBondContact N-O 3.33Å; S81-Y89 PolarHBondContact OG-N 3.43Å; S81-Y89 PolarHBondContact OG-O 3.09Å; R87-Y89 HydrophobicContact CG-CD1 3.94Å; Y89-Y91 HydrophobicContact CE2-CE1 4.2Å; Y89-P106 HydrophobicContact CD2-CG 3.72Å; Y89-P106 HydrophobicContact CE2-CG 3.33Å; Y89-E108 HydrophobicContact CE1-CB 4.36Å; Y89-E108 HydrophobicContact CE1-CG 3.99Å; Y89-E108 WeakPolarHBondContact OH-CB 3.48Å; Y89-D109 PolarHBondContact OH-OD2 2.63Å
90T98.3Very high93.2Very high14 Ų1441.7 Ų41.79%0.08622%0.22CC..  trans-122.5175.9163.481.10000109.8A92 D93 T136T90-A92 VanDerWaalsContact C-N 3.27Å; T90-A92 PolarHBondContact OG1-N 2.79Å; T90-D93 WeakPolarHBondContact CB-OD1 3.46Å; T90-D93 WeakPolarHBondContact CG2-OD1 3.28Å; T90-D93 PolarHBondContact N-OD1 2.78Å; T90-D93 PolarHBondContact N-OD2 3.36Å; T90-D93 VanDerWaalsContact OG1-CG 3.26Å; T90-D93 PolarHBondContact OG1-OD1 3.25Å; T90-T136 HydrophobicContact CG2-CG2 4.13Å
91Y98.6Very high93.1Very high4 Ų448.7 Ų48.72%0.01625%0.252CS..SBendtrans-80-9.4176.1-54.6-43.6000113M79 A80 Y89 F103 S104 L105 D109 K113 Y168 F172M79-Y91 HydrophobicContact CB-CE2 4.3Å; A80-Y91 HydrophobicContact CB-CD1 4Å; A80-Y91 HydrophobicContact CB-CD2 4.38Å; A80-Y91 HydrophobicContact CB-CE1 3.73Å; A80-Y91 HydrophobicContact CB-CE2 4.12Å; A80-Y91 HydrophobicContact CB-CG 4.32Å; A80-Y91 PolarHBondContact N-OH 2.99Å; Y89-Y91 HydrophobicContact CE2-CE1 4.2Å; Y91-F103 VanDerWaalsContact CB-CE2 3.43Å; Y91-F103 AromaticContact CD2-CE2 3.79Å; Y91-F103 HydrophobicContact CD2-CE2 3.79Å; Y91-F103 AromaticContact CD2-CZ 3.54Å; Y91-F103 HydrophobicContact CD2-CZ 3.54Å; Y91-F103 HydrophobicContact CE2-CZ 4.46Å; Y91-F103 HydrophobicContact CG-CE2 4.04Å; Y91-F103 AromaticContact CG-CZ 3.84Å; Y91-F103 HydrophobicContact CG-CZ 3.84Å; Y91-F103 CarbonylContact O-C 3.26Å; Y91-F103 VanDerWaalsContact O-CA 3.26Å; Y91-F103 WeakPolarHBondContact O-CA 3.47Å; Y91-S104 WeakPolarHBondContact CA-O 3.48Å; Y91-S104 WeakPolarHBondContact CB-O 3.44Å; Y91-S104 WeakPolarHBondContact CD1-O 3.41Å; Y91-S104 PolarHBondContact O-N 3.36Å; Y91-L105 HydrophobicContact CD1-CD2 3.92Å; Y91-L105 HydrophobicContact CD2-CD2 4.37Å; Y91-L105 HydrophobicContact CE1-CD2 3.66Å; Y91-L105 HydrophobicContact CE2-CD2 4.14Å; Y91-L105 HydrophobicContact CG-CD2 4.27Å; Y91-D109 WeakPolarHBondContact CE1-OD2 3.4Å; Y91-D109 PolarHBondContact OH-OD1 3.44Å; Y91-K113 PolarHBondContact OH-NZ 3.46Å; Y91-Y168 WeakPolarHBondContact CB-OH 3.35Å; Y91-Y168 AromaticContact CD2-CE1 3.81Å; Y91-Y168 HydrophobicContact CD2-CE1 3.81Å; Y91-Y168 HydrophobicContact CD2-CE2 4.31Å; Y91-Y168 AromaticContact CD2-CZ 3.48Å; Y91-Y168 VanDerWaalsContact CD2-CZ 3.48Å; Y91-Y168 WeakPolarHBondContact CD2-OH 3.26Å; Y91-Y168 HydrophobicContact CE2-CE1 4.48Å; Y91-Y168 HydrophobicContact CG-CE2 4.48Å; Y91-Y168 AromaticContact CG-CZ 3.94Å; Y91-Y168 VanDerWaalsContact CG-OH 3.31Å; Y91-Y168 PolarHBondContact N-OH 2.9Å; Y91-F172 HydrophobicContact CD2-CD2 4.33Å; Y91-F172 HydrophobicContact CE2-CB 4.35Å; Y91-F172 AromaticContact CE2-CD2 3.43Å; Y91-F172 HydrophobicContact CE2-CD2 3.43Å; Y91-F172 VanDerWaalsContact CE2-CD2 3.43Å; Y91-F172 HydrophobicContact CE2-CE2 4.11Å; Y91-F172 HydrophobicContact CE2-CG 4.25Å; Y91-F172 AromaticContact CZ-CD2 3.98Å
92A97.4Very high93.1Very high1 Ų152.6 Ų52.61%0.00827%0.273CS..  trans-142.952.8-173.100000112.4T90 T94 L100 F103 P138 Y168T90-A92 VanDerWaalsContact C-N 3.27Å; T90-A92 PolarHBondContact OG1-N 2.79Å; A92-T94 PolarHBondContact O-N 2.86Å; A92-L100 HydrophobicContact CB-CD2 3.84Å; A92-F103 HydrophobicContact CB-CD2 4.41Å; A92-P138 HydrophobicContact CB-CG 4.01Å; A92-P138 WeakPolarHBondContact O-CB 3.33Å; A92-Y168 HydrophobicContact CB-CD2 4.07Å; A92-Y168 HydrophobicContact CB-CE2 3.91Å
93D92.6Very high93.3Very high87 Ų8754 Ų5447%0.46528%0.279SS..  trans-73.9-6.3-178.3-71.4-34.5000114.1T90T90-D93 WeakPolarHBondContact CB-OD1 3.46Å; T90-D93 WeakPolarHBondContact CG2-OD1 3.28Å; T90-D93 PolarHBondContact N-OD1 2.78Å; T90-D93 PolarHBondContact N-OD2 3.36Å; T90-D93 VanDerWaalsContact OG1-CG 3.26Å; T90-D93 PolarHBondContact OG1-OD1 3.25Å
94T91.3Very high93.6Very high56 Ų5657.4 Ų57.434%0.34430%0.303SS..SBendtrans-63.1129.1174.4-59.50000110.2A92 N102 R140A92-T94 PolarHBondContact O-N 2.86Å; T94-N102 HydrophobicContact CG2-CB 4.47Å; T94-N102 WeakPolarHBondContact CG2-ND2 3.32Å; T94-N102 WeakPolarHBondContact OG1-CB 3.46Å; T94-N102 PolarHBondContact OG1-ND2 3.38Å; T94-R140 PolarHBondContact O-NE 3.39Å
95P84.8Confident93.9Very high99 Ų9958.5 Ų58.564%0.64331%0.309SS*.THydrogen-bonded Turntrans-56.8145.2176.8-25.935000113D97P95-D97 PolarHBondContact O-N 2.92Å
96D78.9Confident94.2Very high125 Ų12559.3 Ų59.367%0.66831%0.314SS*.THydrogen-bonded Turntrans54.915.7173.6-56.8-36.2000117.7F98D96-F98 VanDerWaalsContact C-N 3.34Å; D96-F98 WeakPolarHBondContact O-CD2 3.31Å; D96-F98 PolarHBondContact O-N 3.12Å
97D91.8Very high94.5Very high16 Ų1660.1 Ų60.19%0.08632%0.316CS..  trans-81.670.2177.5-175.718.5000113P95 Q99 L100 H101 N102 R140P95-D97 PolarHBondContact O-N 2.92Å; D97-Q99 PolarHBondContact O-N 2.91Å; D97-Q99 PolarHBondContact OD1-N 2.87Å; D97-L100 PolarHBondContact O-N 3.26Å; D97-L100 WeakPolarHBondContact OD1-CA 3.38Å; D97-L100 PolarHBondContact OD1-N 3.17Å; D97-L100 VanDerWaalsContact OD2-C 3.29Å; D97-L100 VanDerWaalsContact OD2-CA 3.26Å; D97-L100 WeakPolarHBondContact OD2-CA 3.31Å; D97-H101 PolarHBondContact OD1-N 3.09Å; D97-H101 PolarHBondContact OD2-N 2.81Å; D97-N102 WeakPolarHBondContact OD2-CB 3.42Å; D97-N102 PolarHBondContact OD2-N 3.04Å; D97-R140 VanDerWaalsContact O-CZ 3.3Å; D97-R140 PolarHBondContact O-NH2 3.24Å
98F94.3Very high94.5Very high41 Ų4157.1 Ų57.118%0.1831%0.306CS..THydrogen-bonded Turntrans-68.6-19.1174.6-66.8-78.8000113.5D96 L100 L141 I160 Y161 T164 R167D96-F98 VanDerWaalsContact C-N 3.34Å; D96-F98 WeakPolarHBondContact O-CD2 3.31Å; D96-F98 PolarHBondContact O-N 3.12Å; F98-L100 VanDerWaalsContact C-N 3.33Å; F98-L141 HydrophobicContact CD1-CD2 4.33Å; F98-L141 HydrophobicContact CE1-CD2 3.98Å; F98-I160 HydrophobicContact CB-CD1 3.93Å; F98-I160 HydrophobicContact CB-CG1 4.23Å; F98-I160 HydrophobicContact CD1-CD1 3.86Å; F98-I160 HydrophobicContact CD1-CG1 3.73Å; F98-I160 HydrophobicContact CD2-CD1 4.16Å; F98-I160 HydrophobicContact CE1-CD1 4.4Å; F98-I160 HydrophobicContact CE1-CG1 4.3Å; F98-I160 HydrophobicContact CE1-CG2 4.25Å; F98-I160 HydrophobicContact CG-CD1 3.72Å; F98-I160 HydrophobicContact CG-CG1 4.06Å; F98-Y161 AromaticContact CE1-CD1 3.77Å; F98-Y161 HydrophobicContact CE1-CD1 3.77Å; F98-Y161 AromaticContact CE1-CE1 3.75Å; F98-Y161 HydrophobicContact CE1-CE1 3.75Å; F98-Y161 HydrophobicContact CZ-CD1 4.31Å; F98-Y161 AromaticContact CZ-CE1 3.81Å; F98-Y161 HydrophobicContact CZ-CE1 3.81Å; F98-T164 HydrophobicContact CD1-CG2 4.42Å; F98-T164 PolarHBondContact O-OG1 3.16Å; F98-R167 PolarHBondContact O-NH2 3.34Å
99Q95.4Very high94.4Very high123 Ų12353 Ų5358%0.57528%0.281SS*.THydrogen-bonded Turntrans-84.2-11176.9-61-58.7-26.100112.8D97 H101D97-Q99 PolarHBondContact O-N 2.91Å; D97-Q99 PolarHBondContact OD1-N 2.87Å; Q99-H101 WeakPolarHBondContact CB-NE2 3.36Å; Q99-H101 PolarHBondContact O-N 3Å
100L97.5Very high94.3Very high3 Ų354.8 Ų54.82%0.01629%0.293CS..  trans58.936.7-178.1-56.2173.9000112A92 D97 F98 N102 F103 T164 R167 Y168 K171A92-L100 HydrophobicContact CB-CD2 3.84Å; D97-L100 PolarHBondContact O-N 3.26Å; D97-L100 WeakPolarHBondContact OD1-CA 3.38Å; D97-L100 PolarHBondContact OD1-N 3.17Å; D97-L100 VanDerWaalsContact OD2-C 3.29Å; D97-L100 VanDerWaalsContact OD2-CA 3.26Å; D97-L100 WeakPolarHBondContact OD2-CA 3.31Å; F98-L100 VanDerWaalsContact C-N 3.33Å; L100-N102 VanDerWaalsContact C-N 3.27Å; L100-F103 HydrophobicContact CB-CB 4.17Å; L100-F103 WeakPolarHBondContact O-CB 3.21Å; L100-F103 PolarHBondContact O-N 3.19Å; L100-T164 HydrophobicContact CD1-CG2 4.38Å; L100-T164 HydrophobicContact CD2-CG2 3.93Å; L100-T164 HydrophobicContact CG-CG2 4.11Å; L100-R167 HydrophobicContact CD1-CB 3.88Å; L100-Y168 HydrophobicContact CD2-CD2 4.29Å; L100-K171 HydrophobicContact CB-CG 4.48Å; L100-K171 HydrophobicContact CD1-CG 4.14Å
101H96.5Very high93.9Very high151 Ų15158.6 Ų58.670%0.69931%0.308SS*.THydrogen-bonded Turntrans-66.1-32.2175.6-69.1167.2000112.1D97 Q99 F103D97-H101 PolarHBondContact OD1-N 3.09Å; D97-H101 PolarHBondContact OD2-N 2.81Å; Q99-H101 WeakPolarHBondContact CB-NE2 3.36Å; Q99-H101 PolarHBondContact O-N 3Å; H101-F103 VanDerWaalsContact C-N 3.32Å
102N96.4Very high93.3Very high84 Ų8459.4 Ų59.445%0.44931%0.313SS..THydrogen-bonded Turntrans-97.315.1-178.8-66.327.7000111.7T94 D97 L100 S104T94-N102 HydrophobicContact CG2-CB 4.47Å; T94-N102 WeakPolarHBondContact CG2-ND2 3.32Å; T94-N102 WeakPolarHBondContact OG1-CB 3.46Å; T94-N102 PolarHBondContact OG1-ND2 3.38Å; D97-N102 WeakPolarHBondContact OD2-CB 3.42Å; D97-N102 PolarHBondContact OD2-N 3.04Å; L100-N102 VanDerWaalsContact C-N 3.27Å; N102-S104 PolarHBondContact O-N 2.82Å
103F98.5Very high92.8Very high30 Ų3059.7 Ų59.713%0.13231%0.314CS..  trans-62.5124.1172.8-176-78.2000109.9Y91 A92 L100 H101 Y168 K171 F172 A175Y91-F103 VanDerWaalsContact CB-CE2 3.43Å; Y91-F103 AromaticContact CD2-CE2 3.79Å; Y91-F103 HydrophobicContact CD2-CE2 3.79Å; Y91-F103 AromaticContact CD2-CZ 3.54Å; Y91-F103 HydrophobicContact CD2-CZ 3.54Å; Y91-F103 HydrophobicContact CE2-CZ 4.46Å; Y91-F103 HydrophobicContact CG-CE2 4.04Å; Y91-F103 AromaticContact CG-CZ 3.84Å; Y91-F103 HydrophobicContact CG-CZ 3.84Å; Y91-F103 CarbonylContact O-C 3.26Å; Y91-F103 VanDerWaalsContact O-CA 3.26Å; Y91-F103 WeakPolarHBondContact O-CA 3.47Å; A92-F103 HydrophobicContact CB-CD2 4.41Å; L100-F103 HydrophobicContact CB-CB 4.17Å; L100-F103 WeakPolarHBondContact O-CB 3.21Å; L100-F103 PolarHBondContact O-N 3.19Å; H101-F103 VanDerWaalsContact C-N 3.32Å; F103-Y168 AromaticContact CD2-CD2 3.84Å; F103-Y168 HydrophobicContact CD2-CD2 3.84Å; F103-Y168 HydrophobicContact CD2-CE2 4Å; F103-Y168 HydrophobicContact CD2-CG 4.46Å; F103-Y168 HydrophobicContact CE2-CD1 4.31Å; F103-Y168 AromaticContact CE2-CD2 3.71Å; F103-Y168 HydrophobicContact CE2-CD2 3.71Å; F103-Y168 HydrophobicContact CE2-CE1 4.31Å; F103-Y168 AromaticContact CE2-CE2 3.73Å; F103-Y168 HydrophobicContact CE2-CE2 3.73Å; F103-Y168 HydrophobicContact CE2-CG 4.03Å; F103-K171 HydrophobicContact CD1-CB 3.93Å; F103-K171 HydrophobicContact CD2-CB 3.72Å; F103-K171 HydrophobicContact CD2-CG 4.45Å; F103-K171 HydrophobicContact CE1-CB 3.95Å; F103-K171 WeakPolarHBondContact CE1-O 3.45Å; F103-K171 HydrophobicContact CE2-CB 3.71Å; F103-K171 HydrophobicContact CG-CB 3.84Å; F103-K171 HydrophobicContact CG-CG 4.38Å; F103-K171 HydrophobicContact CZ-CB 3.85Å; F103-F172 HydrophobicContact CZ-CB 4.01Å; F103-A175 HydrophobicContact CE1-CB 4.07Å
104S98.2Very high92.8Very high75 Ų7555.8 Ų55.852%0.52429%0.293SS..  trans-153.2151.3175.856.60000112.5Y91 N102Y91-S104 WeakPolarHBondContact CA-O 3.48Å; Y91-S104 WeakPolarHBondContact CB-O 3.44Å; Y91-S104 WeakPolarHBondContact CD1-O 3.41Å; Y91-S104 PolarHBondContact O-N 3.36Å; N102-S104 PolarHBondContact O-N 2.82Å
105L98.4Very high92.8Very high25 Ų2555.6 Ų55.613%0.13129%0.293CS..  trans-84.1124.7171.1-63.7-176.3000109.3Y91 D109 T110 I114 A175 Y176Y91-L105 HydrophobicContact CD1-CD2 3.92Å; Y91-L105 HydrophobicContact CD2-CD2 4.37Å; Y91-L105 HydrophobicContact CE1-CD2 3.66Å; Y91-L105 HydrophobicContact CE2-CD2 4.14Å; Y91-L105 HydrophobicContact CG-CD2 4.27Å; L105-D109 HydrophobicContact CB-CB 3.85Å; L105-D109 HydrophobicContact CD1-CB 4.42Å; L105-D109 HydrophobicContact CD2-CB 4.29Å; L105-D109 HydrophobicContact CG-CB 4.41Å; L105-T110 HydrophobicContact CB-CG2 3.88Å; L105-I114 HydrophobicContact CD1-CD1 3.86Å; L105-A175 HydrophobicContact CD1-CB 3.64Å; L105-A175 HydrophobicContact CD2-CB 4.23Å; L105-A175 HydrophobicContact CG-CB 3.76Å; L105-Y176 HydrophobicContact CD1-CD2 3.76Å; L105-Y176 HydrophobicContact CD1-CE2 3.79Å; L105-Y176 HydrophobicContact CD2-CD2 4.25Å; L105-Y176 HydrophobicContact CD2-CE2 3.92Å
106P96.1Very high92.8Very high29 Ų2950.9 Ų50.919%0.18826%0.262CS..  trans-78.6-174177.233.9-36000111.8Y89 E108 D109 T110Y89-P106 HydrophobicContact CD2-CG 3.72Å; Y89-P106 HydrophobicContact CE2-CG 3.33Å; P106-E108 VanDerWaalsContact C-N 3.3Å; P106-E108 WeakPolarHBondContact CB-OE2 3.45Å; P106-E108 PolarHBondContact O-N 2.79Å; P106-D109 PolarHBondContact O-N 2.88Å; P106-D109 VanDerWaalsContact O-N 3.11Å; P106-T110 PolarHBondContact O-N 2.86Å; P106-T110 PolarHBondContact O-OG1 3.33Å
107E94.3Very high93.3Very high99 Ų9945 Ų4546%0.46323%0.231SC..Hα-helixtrans-65.1-30.9-178-58.7-158.616400113.4D109 T110 K111 L112E107-D109 PolarHBondContact O-N 2.9Å; E107-T110 WeakPolarHBondContact CA-OG1 3.36Å; E107-T110 PolarHBondContact O-N 3.31Å; E107-K111 HydrophobicContact CB-CD 4.14Å; E107-K111 HydrophobicContact CB-CG 4.27Å; E107-K111 VanDerWaalsContact CD-CE 3.41Å; E107-K111 HydrophobicContact CG-CD 4.23Å; E107-K111 WeakPolarHBondContact O-CA 3.49Å; E107-K111 WeakPolarHBondContact O-CB 3.18Å; E107-K111 PolarHBondContact O-N 2.75Å; E107-K111 WeakPolarHBondContact OE1-CE 3.27Å; E107-K111 IonicContact OE1-NZ 3.77Å; E107-K111 PolarHBondContact OE1-NZ 3.43Å; E107-K111 WeakPolarHBondContact OE2-CE 3.39Å; E107-K111 IonicContact OE2-NZ 2.85Å; E107-K111 PolarHBondContact OE2-NZ 2.85Å; E107-L112 PolarHBondContact O-N 2.77Å
108E92.3Very high93.3Very high40 Ų4046.6 Ų46.619%0.18724%0.238CC..Iπ-helixtrans-57.5-32.2173.3-7081.4173.200111.8R87 Y89 P106 L112 K113R87-E108 IonicContact CZ-OE1 3.66Å; R87-E108 VanDerWaalsContact CZ-OE1 3.25Å; R87-E108 IonicContact CZ-OE2 3.47Å; R87-E108 IonicContact NE-OE1 2.7Å; R87-E108 PolarHBondContact NE-OE1 3.41Å; R87-E108 IonicContact NE-OE2 2.93Å; R87-E108 IonicContact NH2-OE1 2.91Å; R87-E108 PolarHBondContact NH2-OE1 2.84Å; R87-E108 VanDerWaalsContact NH2-OE1 3.11Å; R87-E108 IonicContact NH2-OE2 3.86Å; R87-E108 PolarHBondContact NH2-OE2 2.89Å; Y89-E108 HydrophobicContact CE1-CB 4.36Å; Y89-E108 HydrophobicContact CE1-CG 3.99Å; Y89-E108 WeakPolarHBondContact OH-CB 3.48Å; P106-E108 VanDerWaalsContact C-N 3.3Å; P106-E108 WeakPolarHBondContact CB-OE2 3.45Å; P106-E108 PolarHBondContact O-N 2.79Å; E108-L112 WeakPolarHBondContact O-CB 3.34Å; E108-K113 WeakPolarHBondContact O-CD 3.11Å; E108-K113 VanDerWaalsContact O-CG 3.22Å; E108-K113 WeakPolarHBondContact O-CG 3.22Å; E108-K113 PolarHBondContact O-N 2.94Å
109D93.6Very high93Very high0 Ų047.6 Ų47.60%024%0.24CC..Iπ-helixtrans-84.7-56.6175.7-74.1-93.6000110.9Y89 Y91 L105 P106 E107 K113 I114 Y176Y89-D109 PolarHBondContact OH-OD2 2.63Å; Y91-D109 WeakPolarHBondContact CE1-OD2 3.4Å; Y91-D109 PolarHBondContact OH-OD1 3.44Å; L105-D109 HydrophobicContact CB-CB 3.85Å; L105-D109 HydrophobicContact CD1-CB 4.42Å; L105-D109 HydrophobicContact CD2-CB 4.29Å; L105-D109 HydrophobicContact CG-CB 4.41Å; P106-D109 PolarHBondContact O-N 2.88Å; P106-D109 VanDerWaalsContact O-N 3.11Å; E107-D109 PolarHBondContact O-N 2.9Å; D109-K113 PolarHBondContact O-N 2.81Å; D109-K113 WeakPolarHBondContact OD1-CE 3.39Å; D109-K113 IonicContact OD1-NZ 2.75Å; D109-K113 PolarHBondContact OD1-NZ 2.69Å; D109-K113 IonicContact OD2-NZ 3.79Å; D109-I114 HydrophobicContact CB-CD1 4.47Å; D109-I114 VanDerWaalsContact O-CB 3.28Å; D109-I114 WeakPolarHBondContact O-CB 3.41Å; D109-I114 WeakPolarHBondContact O-CG1 3.25Å; D109-I114 PolarHBondContact O-N 3.49Å; D109-Y176 WeakPolarHBondContact OD1-CE2 3.38Å; D109-Y176 PolarHBondContact OD1-OH 2.98Å
110T95.6Very high92.4Very high48 Ų4841.8 Ų41.829%0.29421%0.214SC..Iπ-helixtrans-76.7-29.4-168.454.90000114.6L105 P106 E107 P115L105-T110 HydrophobicContact CB-CG2 3.88Å; P106-T110 PolarHBondContact O-N 2.86Å; P106-T110 PolarHBondContact O-OG1 3.33Å; E107-T110 WeakPolarHBondContact CA-OG1 3.36Å; E107-T110 PolarHBondContact O-N 3.31Å; T110-P115 WeakPolarHBondContact O-CD 3.42Å
111K90.6Very high91.9Very high94 Ų9444.4 Ų44.441%0.40923%0.227SC..Iπ-helixtrans-105.5-22.1-179.6-59.9-171-173.51670113.6W36 E107W36-K111 HydrophobicContact CH2-CD 4.37Å; E107-K111 HydrophobicContact CB-CD 4.14Å; E107-K111 HydrophobicContact CB-CG 4.27Å; E107-K111 VanDerWaalsContact CD-CE 3.41Å; E107-K111 HydrophobicContact CG-CD 4.23Å; E107-K111 WeakPolarHBondContact O-CA 3.49Å; E107-K111 WeakPolarHBondContact O-CB 3.18Å; E107-K111 PolarHBondContact O-N 2.75Å; E107-K111 WeakPolarHBondContact OE1-CE 3.27Å; E107-K111 IonicContact OE1-NZ 3.77Å; E107-K111 PolarHBondContact OE1-NZ 3.43Å; E107-K111 WeakPolarHBondContact OE2-CE 3.39Å; E107-K111 IonicContact OE2-NZ 2.85Å; E107-K111 PolarHBondContact OE2-NZ 2.85Å
112L84.4Confident91.6Very high21 Ų2144.6 Ų44.611%0.1123%0.228CC..Iπ-helixtrans-111.7-71.7-179-44.3177.4000111.3L29 Q32 A33 E107 E108 I114 P115 L116L29-L112 HydrophobicContact CB-CB 4.38Å; L29-L112 HydrophobicContact CD2-CB 3.38Å; Q32-L112 HydrophobicContact CB-CD2 4.01Å; A33-L112 HydrophobicContact CB-CD1 4.32Å; E107-L112 PolarHBondContact O-N 2.77Å; E108-L112 WeakPolarHBondContact O-CB 3.34Å; L112-I114 PolarHBondContact O-N 3.19Å; L112-P115 WeakPolarHBondContact O-CD 3.34Å; L112-L116 VanDerWaalsContact O-CG 3.25Å; L112-L116 WeakPolarHBondContact O-CG 3.4Å; L112-L116 PolarHBondContact O-N 3.11Å; L112-L116 VanDerWaalsContact O-N 3.14Å
113K87.4Confident90.9Very high7 Ų742.2 Ų42.23%0.0322%0.215CC..Iπ-helixtrans-57.5-55.4-171.4-69.5157.370.8-170.40112.7L29 P78 Y91 E108 D109 L116 I117 Y176L29-K113 HydrophobicContact CD1-CB 4.37Å; L29-K113 HydrophobicContact CD1-CD 4.05Å; L29-K113 HydrophobicContact CD1-CG 3.21Å; L29-K113 VanDerWaalsContact CD2-CA 3.42Å; L29-K113 HydrophobicContact CD2-CB 4.19Å; L29-K113 HydrophobicContact CD2-CG 3.69Å; L29-K113 HydrophobicContact CG-CG 4.07Å; P78-K113 PolarHBondContact O-NZ 3.15Å; Y91-K113 PolarHBondContact OH-NZ 3.46Å; E108-K113 WeakPolarHBondContact O-CD 3.11Å; E108-K113 VanDerWaalsContact O-CG 3.22Å; E108-K113 WeakPolarHBondContact O-CG 3.22Å; E108-K113 PolarHBondContact O-N 2.94Å; D109-K113 PolarHBondContact O-N 2.81Å; D109-K113 WeakPolarHBondContact OD1-CE 3.39Å; D109-K113 IonicContact OD1-NZ 2.75Å; D109-K113 PolarHBondContact OD1-NZ 2.69Å; D109-K113 IonicContact OD2-NZ 3.79Å; K113-L116 PolarHBondContact O-N 2.85Å; K113-I117 WeakPolarHBondContact O-CD1 3.49Å; K113-I117 WeakPolarHBondContact O-CG1 3.23Å; K113-I117 PolarHBondContact O-N 2.93Å; K113-Y176 VanDerWaalsContact CE-OH 3.24Å; K113-Y176 WeakPolarHBondContact CE-OH 3.41Å; K113-Y176 PolarHBondContact NZ-OH 2.98Å
114I93.4Very high90.1Very high5 Ų541.7 Ų41.73%0.02622%0.216CC..Hα-helixtrans-63.9-49.3-172.4-71.1165.4000111.2L105 D109 L112 L116 I117 H118 Y176 H179 L181L105-I114 HydrophobicContact CD1-CD1 3.86Å; D109-I114 HydrophobicContact CB-CD1 4.47Å; D109-I114 VanDerWaalsContact O-CB 3.28Å; D109-I114 WeakPolarHBondContact O-CB 3.41Å; D109-I114 WeakPolarHBondContact O-CG1 3.25Å; D109-I114 PolarHBondContact O-N 3.49Å; L112-I114 PolarHBondContact O-N 3.19Å; I114-L116 PolarHBondContact O-N 2.82Å; I114-I117 PolarHBondContact O-N 2.88Å; I114-H118 PolarHBondContact O-CD2 2.89Å; I114-H118 VanDerWaalsContact O-CD2 3.23Å; I114-H118 PolarHBondContact O-N 2.94Å; I114-Y176 HydrophobicContact CD1-CE1 4.33Å; I114-Y176 HydrophobicContact CD1-CE2 4.24Å; I114-Y176 HydrophobicContact CG1-CD1 4.24Å; I114-Y176 HydrophobicContact CG1-CE1 3.77Å; I114-Y176 HydrophobicContact CG1-CE2 4.5Å; I114-H179 HydrophobicContact CD1-CB 4.07Å; I114-H179 HydrophobicContact CG2-CB 3.76Å; I114-L181 HydrophobicContact CB-CD1 4.29Å; I114-L181 HydrophobicContact CG1-CD1 4.01Å; I114-L181 HydrophobicContact CG2-CD1 4.07Å
115P91.1Very high89.5Confident52 Ų5245.7 Ų45.734%0.33823%0.227SC..Hα-helixtrans-57.8-43174.6-2937.8000113.8T110 L112 H118 R119T110-P115 WeakPolarHBondContact O-CD 3.42Å; L112-P115 WeakPolarHBondContact O-CD 3.34Å; P115-H118 PolarHBondContact O-N 2.73Å; P115-R119 WeakPolarHBondContact O-CG 2.99Å; P115-R119 PolarHBondContact O-N 2.86Å
116L84.6Confident88.9Confident1 Ų148 Ų481%0.00523%0.234CC..Hα-helixtrans-63.7-42.9177.8-69-167.3000112.5L25 L28 L29 E57 I61 L112 K113 I114 H118 R119 A120L25-L116 HydrophobicContact CD1-CB 4.33Å; L25-L116 HydrophobicContact CD2-CB 4.34Å; L25-L116 HydrophobicContact CD2-CD1 4.38Å; L28-L116 HydrophobicContact CB-CD1 4.14Å; L28-L116 HydrophobicContact CD2-CD1 3.8Å; L28-L116 HydrophobicContact CD2-CD2 4.43Å; L28-L116 HydrophobicContact CG-CD1 4.5Å; L29-L116 HydrophobicContact CD2-CD1 3.38Å; L29-L116 HydrophobicContact CD2-CG 4.08Å; L29-L116 HydrophobicContact CG-CD1 3.96Å; E57-L116 HydrophobicContact CG-CD2 3.88Å; E57-L116 WeakPolarHBondContact OE1-CD2 3.38Å; I61-L116 HydrophobicContact CD1-CD2 4.12Å; L112-L116 VanDerWaalsContact O-CG 3.25Å; L112-L116 WeakPolarHBondContact O-CG 3.4Å; L112-L116 PolarHBondContact O-N 3.11Å; L112-L116 VanDerWaalsContact O-N 3.14Å; K113-L116 PolarHBondContact O-N 2.85Å; I114-L116 PolarHBondContact O-N 2.82Å; L116-H118 VanDerWaalsContact C-N 3.33Å; L116-H118 PolarHBondContact O-N 3.47Å; L116-R119 PolarHBondContact O-N 2.7Å; L116-A120 PolarHBondContact O-N 3.3Å
117I88.8Confident88.6Confident0 Ų051.5 Ų51.50%026%0.256CS..Hα-helixtrans-58.8-49.3175.9-66.9162.8000109L25 I75 V77 K113 I114 R119 A120 L121 L130 Y176 L181L25-I117 HydrophobicContact CD1-CB 4.32Å; L25-I117 HydrophobicContact CD1-CD1 4.29Å; L25-I117 HydrophobicContact CD1-CG1 3.28Å; I75-I117 HydrophobicContact CD1-CG2 4.5Å; I75-I117 HydrophobicContact CG2-CG1 4.45Å; V77-I117 HydrophobicContact CG1-CD1 4.36Å; V77-I117 HydrophobicContact CG2-CD1 3.78Å; K113-I117 WeakPolarHBondContact O-CD1 3.49Å; K113-I117 WeakPolarHBondContact O-CG1 3.23Å; K113-I117 PolarHBondContact O-N 2.93Å; I114-I117 PolarHBondContact O-N 2.88Å; I117-R119 VanDerWaalsContact C-N 3.33Å; I117-R119 PolarHBondContact O-N 3.17Å; I117-A120 WeakPolarHBondContact O-CB 3.11Å; I117-A120 PolarHBondContact O-N 3Å; I117-L121 HydrophobicContact CG2-CD1 4.05Å; I117-L121 HydrophobicContact CG2-CG 4.07Å; I117-L121 VanDerWaalsContact O-CG 3.29Å; I117-L121 WeakPolarHBondContact O-CG 3.25Å; I117-L121 PolarHBondContact O-N 2.77Å; I117-L130 HydrophobicContact CG2-CD1 4.04Å; I117-L130 HydrophobicContact CG2-CD2 3.83Å; I117-Y176 HydrophobicContact CD1-CE1 4.11Å; I117-L181 HydrophobicContact CB-CD1 4.08Å; I117-L181 HydrophobicContact CB-CD2 4.44Å; I117-L181 HydrophobicContact CD1-CD1 4.05Å; I117-L181 HydrophobicContact CG2-CD1 3.9Å; I117-L181 HydrophobicContact CG2-CD2 3.59Å; I117-L181 HydrophobicContact CG2-CG 4.4Å
118H92.7Very high88.3Confident51 Ų5148 Ų4824%0.23624%0.242CC..Hα-helixtrans-56.8-43.5177.8-82.2-60.7000112.9I114 P115 L116 A120 L121 Q122 H179 L181I114-H118 PolarHBondContact O-CD2 2.89Å; I114-H118 VanDerWaalsContact O-CD2 3.23Å; I114-H118 PolarHBondContact O-N 2.94Å; P115-H118 PolarHBondContact O-N 2.73Å; L116-H118 VanDerWaalsContact C-N 3.33Å; L116-H118 PolarHBondContact O-N 3.47Å; H118-A120 VanDerWaalsContact C-N 3.34Å; H118-A120 PolarHBondContact O-N 3.21Å; H118-L121 PolarHBondContact O-N 2.94Å; H118-Q122 WeakPolarHBondContact O-CB 3.41Å; H118-Q122 VanDerWaalsContact O-CG 3.22Å; H118-Q122 WeakPolarHBondContact O-CG 3.48Å; H118-Q122 PolarHBondContact O-N 3.07Å; H118-H179 PolarHBondContact CE1-O 2.99Å; H118-H179 VanDerWaalsContact CE1-O 3.25Å; H118-H179 PolarHBondContact NE2-O 2.87Å; H118-L181 VanDerWaalsContact CE1-CD2 3.46Å; H118-L181 WeakPolarHBondContact CE1-CD2 3.24Å
119R87.3Confident88.3Confident61 Ų6147.1 Ų47.123%0.2324%0.24CC..Hα-helixtrans-60.9-43.3175-68.417884161.616.1111.6D54 E57 I61 P115 L116 I117 Q122 L123D54-R119 IonicContact OD1-CZ 3.67Å; D54-R119 IonicContact OD1-NH1 3.6Å; D54-R119 PolarHBondContact OD1-NH1 3.21Å; D54-R119 IonicContact OD1-NH2 3.37Å; D54-R119 PolarHBondContact OD1-NH2 3.44Å; E57-R119 IonicContact OE1-CZ 3.5Å; E57-R119 IonicContact OE1-NE 2.82Å; E57-R119 IonicContact OE1-NH1 2.99Å; E57-R119 PolarHBondContact OE1-NH1 3.16Å; E57-R119 IonicContact OE2-NH1 3.77Å; I61-R119 HydrophobicContact CD1-CB 4.1Å; P115-R119 WeakPolarHBondContact O-CG 2.99Å; P115-R119 PolarHBondContact O-N 2.86Å; L116-R119 PolarHBondContact O-N 2.7Å; I117-R119 VanDerWaalsContact C-N 3.33Å; I117-R119 PolarHBondContact O-N 3.17Å; R119-Q122 PolarHBondContact O-N 3.21Å; R119-L123 WeakPolarHBondContact O-CG 3.11Å; R119-L123 PolarHBondContact O-N 3.37Å; R119-L123 VanDerWaalsContact O-N 3.1Å
120A83.1Confident88.5Confident2 Ų247.2 Ų47.22%0.01724%0.241CC..Hα-helixtrans-63.2-44.2177.600000112.1I61 I75 L116 I117 H118 Q122 L123 A124I61-A120 VanDerWaalsContact CG2-CA 3.47Å; I61-A120 HydrophobicContact CG2-CB 3.75Å; I75-A120 HydrophobicContact CD1-CB 3.77Å; L116-A120 PolarHBondContact O-N 3.3Å; I117-A120 WeakPolarHBondContact O-CB 3.11Å; I117-A120 PolarHBondContact O-N 3Å; H118-A120 VanDerWaalsContact C-N 3.34Å; H118-A120 PolarHBondContact O-N 3.21Å; A120-Q122 VanDerWaalsContact C-N 3.34Å; A120-Q122 PolarHBondContact O-N 3.34Å; A120-L123 PolarHBondContact O-N 3.32Å; A120-A124 WeakPolarHBondContact O-CB 3.49Å; A120-A124 PolarHBondContact O-N 2.77Å
121L86.7Confident88.5Confident57 Ų5745 Ų4530%0.29823%0.227SC..Hα-helixtrans-61.6-40.4176-63.7-174.4000112.1I117 H118 L123 A124 V128 L181I117-L121 HydrophobicContact CG2-CD1 4.05Å; I117-L121 HydrophobicContact CG2-CG 4.07Å; I117-L121 VanDerWaalsContact O-CG 3.29Å; I117-L121 WeakPolarHBondContact O-CG 3.25Å; I117-L121 PolarHBondContact O-N 2.77Å; H118-L121 PolarHBondContact O-N 2.94Å; L121-L123 VanDerWaalsContact C-N 3.33Å; L121-A124 PolarHBondContact O-N 3.35Å; L121-V128 HydrophobicContact CD2-CB 3.42Å; L121-V128 VanDerWaalsContact CD2-CB 3.42Å; L121-V128 HydrophobicContact CD2-CG1 3.83Å; L121-V128 HydrophobicContact CD2-CG2 3.95Å; L121-L181 HydrophobicContact CD1-CD2 3.58Å
122Q89.5Confident88.9Confident156 Ų15640.5 Ų40.573%0.72921%0.207SC*.Hα-helixtrans-67.9-32.5178.5-73.21698.300113H118 R119 A120H118-Q122 WeakPolarHBondContact O-CB 3.41Å; H118-Q122 VanDerWaalsContact O-CG 3.22Å; H118-Q122 WeakPolarHBondContact O-CG 3.48Å; H118-Q122 PolarHBondContact O-N 3.07Å; R119-Q122 PolarHBondContact O-N 3.21Å; A120-Q122 VanDerWaalsContact C-N 3.34Å; A120-Q122 PolarHBondContact O-N 3.34Å
123L83.3Confident89.6Confident33 Ų3339.5 Ų39.517%0.17320%0.202CC..Hα-helixtrans-83-23.2178.8-73.5171.7000112.9Y58 I61 C65 T66 R119 A120 L121Y58-L123 HydrophobicContact CD2-CD1 4.19Å; Y58-L123 HydrophobicContact CE2-CD1 3.89Å; Y58-L123 HydrophobicContact CE2-CD2 3.96Å; Y58-L123 HydrophobicContact CE2-CG 4.42Å; I61-L123 HydrophobicContact CB-CD1 4.16Å; I61-L123 HydrophobicContact CG2-CD1 3.57Å; C65-L123 HydrophobicContact CB-CB 4.44Å; T66-L123 HydrophobicContact CG2-CB 3.89Å; T66-L123 HydrophobicContact CG2-CD2 4.04Å; T66-L123 HydrophobicContact CG2-CG 4.46Å; R119-L123 WeakPolarHBondContact O-CG 3.11Å; R119-L123 PolarHBondContact O-N 3.37Å; R119-L123 VanDerWaalsContact O-N 3.1Å; A120-L123 PolarHBondContact O-N 3.32Å; L121-L123 VanDerWaalsContact C-N 3.33Å
124A81.4Confident90.1Very high19 Ų1939.1 Ų39.116%0.15720%0.201CC..  trans-71.8129.7-179.100000111.6C65 A120 L121 R126 V128C65-A124 HydrophobicContact CB-CB 4.42Å; C65-A124 WeakPolarHBondContact O-CA 3.04Å; A120-A124 WeakPolarHBondContact O-CB 3.49Å; A120-A124 PolarHBondContact O-N 2.77Å; L121-A124 PolarHBondContact O-N 3.35Å; A124-R126 WeakPolarHBondContact CB-O 3.24Å; A124-V128 HydrophobicContact CB-CG2 3.39Å
125Q84.4Confident90.3Very high160 Ų16039 Ų3975%0.74820%0.2SC*.SBendtrans-85.5-17170.3-66.5179-0.600112.2
126R85.9Confident90.7Very high74 Ų7436.9 Ų36.928%0.27919%0.186SC..SBendtrans-103.3147.7177.9-63.5175.2-178.4167.6-2.7108.7G71 N73 A124 V128 S380 K381G71-R126 PolarHBondContact O-NH1 2.91Å; G71-R126 VanDerWaalsContact O-NH1 3.12Å; N73-R126 HydrophobicContact CB-CB 4.46Å; A124-R126 WeakPolarHBondContact CB-O 3.24Å; R126-V128 PolarHBondContact O-N 2.68Å; R126-S380 PolarHBondContact NH1-O 2.98Å; R126-K381 PolarHBondContact NH2-O 2.73Å
127P89.7Confident91.3Very high101 Ų10136.8 Ų36.866%0.65619%0.185SC*.  trans-53.7132.2167.3-22.733.6000110
128V88.2Confident91.8Very high26 Ų2636.8 Ų36.816%0.15819%0.185CC..  trans-106.7128.9178.51790000108.8N73 I75 L121 A124 R126N73-V128 CarbonylContact O-C 3.5Å; N73-V128 VanDerWaalsContact O-CA 3.28Å; N73-V128 WeakPolarHBondContact O-CA 3.43Å; I75-V128 HydrophobicContact CB-CG1 4.48Å; I75-V128 HydrophobicContact CD1-CG1 3.83Å; I75-V128 HydrophobicContact CG1-CG1 3.76Å; L121-V128 HydrophobicContact CD2-CB 3.42Å; L121-V128 VanDerWaalsContact CD2-CB 3.42Å; L121-V128 HydrophobicContact CD2-CG1 3.83Å; L121-V128 HydrophobicContact CD2-CG2 3.95Å; A124-V128 HydrophobicContact CB-CG2 3.39Å; R126-V128 PolarHBondContact O-N 2.68Å
129S93.6Very high92Very high21 Ų2137.1 Ų37.115%0.14719%0.191CC..EExtended strand (participates in β ladder)trans-94128.2177.4-68.90000110.8N73 I74 I75N73-S129 PolarHBondContact O-N 3.19Å; I74-S129 CarbonylContact C-O 3.37Å; I74-S129 VanDerWaalsContact CA-O 3.24Å; I74-S129 WeakPolarHBondContact CA-O 3.44Å; I75-S129 PolarHBondContact N-O 3.39Å
130L96.3Very high92.3Very high3 Ų335.6 Ų35.62%0.01619%0.185CC..EExtended strand (participates in β ladder)trans-91.1130.7172.4-49-178000110I75 I117 L181 F183 W184 A185I75-L130 HydrophobicContact CB-CD2 3.8Å; I75-L130 HydrophobicContact CD1-CD2 4.25Å; I75-L130 HydrophobicContact CG1-CD2 4.45Å; I75-L130 HydrophobicContact CG2-CD2 4.39Å; I75-L130 WeakPolarHBondContact O-CA 3.44Å; I117-L130 HydrophobicContact CG2-CD1 4.04Å; I117-L130 HydrophobicContact CG2-CD2 3.83Å; L130-L181 HydrophobicContact CD1-CB 3.98Å; L130-L181 HydrophobicContact CD1-CD2 4.27Å; L130-F183 HydrophobicContact CB-CD1 3.55Å; L130-F183 HydrophobicContact CB-CE1 3.66Å; L130-F183 HydrophobicContact CB-CG 4.16Å; L130-F183 HydrophobicContact CB-CZ 4.38Å; L130-F183 HydrophobicContact CD1-CZ 4.45Å; L130-W184 PolarHBondContact O-N 3.4Å; L130-A185 PolarHBondContact O-N 2.96Å
131L97.1Very high93Very high0 Ų035.5 Ų35.50%018%0.184CC..EExtended strand (participates in β ladder)trans-115.9135.7172.4172.260.4000108.3I75 W76 V77 W184 A185 T187 L235 F293I75-L131 PolarHBondContact O-N 3.31Å; W76-L131 CarbonylContact C-O 3.14Å; W76-L131 WeakPolarHBondContact CA-O 3.28Å; V77-L131 PolarHBondContact N-O 3.27Å; L131-W184 HydrophobicContact CB-CE3 4.3Å; L131-W184 HydrophobicContact CB-CZ3 4.4Å; L131-W184 HydrophobicContact CD2-CZ3 4.44Å; L131-A185 WeakPolarHBondContact CA-O 3.32Å; L131-A185 HydrophobicContact CD1-CB 3.66Å; L131-T187 HydrophobicContact CD1-CG2 3.85Å; L131-L235 HydrophobicContact CD1-CD1 4.06Å; L131-L235 HydrophobicContact CD2-CD1 4.44Å; L131-F293 HydrophobicContact CD2-CD1 4.21Å; L131-F293 HydrophobicContact CD2-CE1 3.58Å; L131-F293 HydrophobicContact CD2-CZ 4.4Å
132A98.3Very high93.5Very high0 Ų032.8 Ų32.80%017%0.17CC..EExtended strand (participates in β ladder)trans-124.9142.5176.700000113.3V77 M79 F172 F183 A185 V186 T187V77-A132 VanDerWaalsContact O-CA 3.24Å; V77-A132 WeakPolarHBondContact O-CA 3.18Å; V77-A132 WeakPolarHBondContact O-CB 3.46Å; M79-A132 HydrophobicContact CG-CB 3.92Å; M79-A132 HydrophobicContact SD-CB 4.25Å; A132-F172 HydrophobicContact CB-CE1 3.54Å; A132-F172 HydrophobicContact CB-CZ 3.78Å; A132-F183 HydrophobicContact CB-CD1 3.74Å; A132-F183 HydrophobicContact CB-CE1 3.43Å; A132-F183 VanDerWaalsContact CB-CE1 3.43Å; A132-F183 HydrophobicContact CB-CZ 4.15Å; A132-A185 PolarHBondContact N-O 3.4Å; A132-A185 VanDerWaalsContact N-O 3.1Å; A132-V186 HydrophobicContact CB-CG1 4.24Å; A132-V186 CarbonylContact O-C 3.59Å; A132-V186 WeakPolarHBondContact O-CA 3.36Å; A132-T187 PolarHBondContact O-N 3.48Å
133S98.4Very high93.8Very high0 Ų029.1 Ų29.10%016%0.159CC..EExtended strand (participates in β ladder)trans-134.9136.4174.1-51.10000110.4W76 V77 M79 W135 T187 D238W76-S133 VanDerWaalsContact CZ2-CB 3.42Å; W76-S133 WeakPolarHBondContact CZ2-OG 3.33Å; W76-S133 PolarHBondContact NE1-OG 2.81Å; V77-S133 PolarHBondContact O-N 3.45Å; M79-S133 PolarHBondContact N-O 3.07Å; S133-W135 WeakPolarHBondContact O-CZ3 3.3Å; S133-T187 WeakPolarHBondContact CB-OG1 3.47Å; S133-T187 VanDerWaalsContact OG-CG2 3.28Å; S133-T187 WeakPolarHBondContact OG-CG2 3.39Å; S133-T187 PolarHBondContact OG-OG1 3.01Å; S133-D238 WeakPolarHBondContact CB-OD2 3.47Å; S133-D238 PolarHBondContact OG-OD2 3.27Å
134P98.6Very high94.3Very high0 Ų032.3 Ų32.30%017%0.171CC..EExtended strand (participates in β ladder)trans-87.8146.1166.732.8-28.8000111.7M79 W165 N190M79-P134 HydrophobicContact CB-CB 3.97Å; M79-P134 HydrophobicContact SD-CB 4.08Å; M79-P134 HydrophobicContact SD-CG 4.07Å; P134-W165 HydrophobicContact CB-CH2 3.66Å; P134-W165 HydrophobicContact CB-CZ2 3.59Å; P134-W165 HydrophobicContact CG-CH2 4.21Å; P134-W165 HydrophobicContact CG-CZ2 3.65Å; P134-N190 WeakPolarHBondContact O-CB 3.36Å; P134-N190 PolarHBondContact O-N 3.04Å
135W98.3Very high94.9Very high2 Ų233.5 Ų33.51%0.00819%0.185CC..SBendtrans-100.2-27.8168.5-73.9-109.1000111.8W76 P78 C82 S133 E189 N190 Q203 C204 L205 W337W76-W135 HydrophobicContact CE3-CH2 4.41Å; W76-W135 AromaticContact CH2-CH2 2.91Å; W76-W135 HydrophobicContact CH2-CH2 2.91Å; W76-W135 AromaticContact CH2-CZ2 3.11Å; W76-W135 HydrophobicContact CH2-CZ2 3.11Å; W76-W135 AromaticContact CH2-CZ3 3.8Å; W76-W135 HydrophobicContact CH2-CZ3 3.8Å; W76-W135 AromaticContact CZ2-CH2 3.94Å; W76-W135 HydrophobicContact CZ2-CH2 3.94Å; W76-W135 HydrophobicContact CZ2-CZ2 4.22Å; W76-W135 HydrophobicContact CZ2-CZ3 4.49Å; W76-W135 AromaticContact CZ3-CH2 3.2Å; W76-W135 HydrophobicContact CZ3-CH2 3.2Å; W76-W135 AromaticContact CZ3-CZ2 3.59Å; W76-W135 HydrophobicContact CZ3-CZ2 3.59Å; W76-W135 HydrophobicContact CZ3-CZ3 4.27Å; P78-W135 HydrophobicContact CB-CE3 4.44Å; P78-W135 HydrophobicContact CB-CH2 3.39Å; P78-W135 HydrophobicContact CB-CZ3 3.26Å; P78-W135 HydrophobicContact CG-CH2 3.63Å; P78-W135 HydrophobicContact CG-CZ3 4.05Å; C82-W135 HydrophobicContact CB-CD2 3.36Å; C82-W135 HydrophobicContact CB-CE3 3.71Å; C82-W135 HydrophobicContact CB-CG 3.91Å; C82-W135 HydrophobicContact CB-CH2 3.56Å; C82-W135 HydrophobicContact CB-CZ2 3.13Å; C82-W135 HydrophobicContact CB-CZ3 3.87Å; S133-W135 WeakPolarHBondContact O-CZ3 3.3Å; W135-E189 WeakPolarHBondContact CA-OE1 3.15Å; W135-N190 VanDerWaalsContact CD1-ND2 3.26Å; W135-N190 HydrophobicContact CD2-CB 4.18Å; W135-N190 HydrophobicContact CG-CB 4.15Å; W135-N190 PolarHBondContact NE1-ND2 3.18Å; W135-Q203 HydrophobicContact CB-CB 3.64Å; W135-Q203 HydrophobicContact CG-CB 4.37Å; W135-Q203 CarbonylContact O-C 3.55Å; W135-C204 CarbonylContact O-C 2.86Å; W135-C204 WeakPolarHBondContact O-CA 3.3Å; W135-C204 PolarHBondContact O-N 2.95Å; W135-C204 VanDerWaalsContact O-N 3.12Å; W135-L205 PolarHBondContact O-N 2.67Å; W135-W337 HydrophobicContact CH2-CH2 4.37Å; W135-W337 AromaticContact CZ2-CH2 3.47Å; W135-W337 HydrophobicContact CZ2-CH2 3.47Å; W135-W337 VanDerWaalsContact CZ2-CH2 3.47Å; W135-W337 AromaticContact CZ2-CZ2 3.74Å; W135-W337 HydrophobicContact CZ2-CZ2 3.74Å; W135-W337 HydrophobicContact CZ2-CZ3 4.46Å
136T98.6Very high95.4Very high7 Ų727.1 Ų27.14%0.04316%0.16CC..  trans-154.4144.5-178.3-144.50000111.7T90 K142 G147 Q203 C204T90-T136 HydrophobicContact CG2-CG2 4.13Å; T136-K142 PolarHBondContact OG1-NZ 3.24Å; T136-G147 PolarHBondContact OG1-O 3.14Å; T136-Q203 HydrophobicContact CG2-CB 4.08Å; T136-Q203 HydrophobicContact CG2-CG 3.95Å; T136-C204 PolarHBondContact OG1-O 3.49Å; T136-C204 VanDerWaalsContact OG1-O 3.04Å
137S98.2Very high95.8Very high0 Ų024.6 Ų24.60%016%0.157CC..  trans-83.3163.3169.860.90000111T139 K142 W165S137-T139 PolarHBondContact O-N 3.02Å; S137-K142 VanDerWaalsContact OG-CG 3.29Å; S137-K142 WeakPolarHBondContact OG-CG 3.5Å; S137-W165 VanDerWaalsContact CA-CZ3 3.47Å; S137-W165 VanDerWaalsContact CB-CE3 3.47Å
138P98Very high96.1Very high0 Ų022.2 Ų22.20%014%0.139CC..  trans-45.7130.2167.2-28.932.8000110.8A92 R140 L141 Y168A92-P138 HydrophobicContact CB-CG 4.01Å; A92-P138 WeakPolarHBondContact O-CB 3.33Å; P138-R140 HydrophobicContact CB-CG 4.17Å; P138-R140 PolarHBondContact O-N 2.86Å; P138-L141 HydrophobicContact CB-CG 4.48Å; P138-L141 HydrophobicContact CG-CD1 4.44Å; P138-L141 WeakPolarHBondContact O-CB 3.27Å; P138-L141 PolarHBondContact O-N 3.29Å; P138-Y168 HydrophobicContact CG-CD2 4.14Å; P138-Y168 HydrophobicContact CG-CE2 3.9Å
139T96.6Very high96.5Very high58 Ų5821 Ų2136%0.35613%0.131SC..G310 helixtrans-55.9-31-168.258.10000113.3S137 L141 K142 G145S137-T139 PolarHBondContact O-N 3.02Å; T139-L141 PolarHBondContact O-N 2.81Å; T139-K142 WeakPolarHBondContact O-CB 3.42Å; T139-K142 PolarHBondContact O-N 3.41Å; T139-G145 WeakPolarHBondContact O-CA 3.49Å
140R94.1Very high96.7Very high28 Ų2825.3 Ų25.311%0.10615%0.147CC..G310 helixtrans-58.4-28.9174.864.4178.4175.577.36.4114.2T94 D97 P138 K142 K154T94-R140 PolarHBondContact O-NE 3.39Å; D97-R140 VanDerWaalsContact O-CZ 3.3Å; D97-R140 PolarHBondContact O-NH2 3.24Å; P138-R140 HydrophobicContact CB-CG 4.17Å; P138-R140 PolarHBondContact O-N 2.86Å; R140-K142 VanDerWaalsContact C-N 3.26Å; R140-K154 WeakPolarHBondContact O-CE 3.19Å; R140-K154 PolarHBondContact O-NZ 3.18Å
141L97.2Very high96.7Very high0 Ų025.2 Ų25.20%015%0.147CC..G310 helixtrans-78.1-12.1177-61.4-176000112.4F98 P138 T139 L153 K154 Y161 T164 W165F98-L141 HydrophobicContact CD1-CD2 4.33Å; F98-L141 HydrophobicContact CE1-CD2 3.98Å; P138-L141 HydrophobicContact CB-CG 4.48Å; P138-L141 HydrophobicContact CG-CD1 4.44Å; P138-L141 WeakPolarHBondContact O-CB 3.27Å; P138-L141 PolarHBondContact O-N 3.29Å; T139-L141 PolarHBondContact O-N 2.81Å; L141-L153 HydrophobicContact CB-CD2 3.89Å; L141-L153 CarbonylContact O-C 3.56Å; L141-L153 WeakPolarHBondContact O-CA 3.13Å; L141-K154 PolarHBondContact O-N 3.13Å; L141-Y161 HydrophobicContact CD2-CD1 3.86Å; L141-T164 HydrophobicContact CD1-CG2 4.23Å; L141-T164 HydrophobicContact CD2-CG2 4.23Å; L141-W165 HydrophobicContact CD1-CB 4.35Å; L141-W165 HydrophobicContact CD1-CE3 4.44Å
142K97.4Very high96.7Very high0 Ų026.8 Ų26.80%016%0.157CC..BIsolated β-bridgetrans-99.6141.8-173.1-55.1-178.869.7-1720111.8T136 S137 T139 R140 K144 G145 A146 G147 G151 K154 C204 L205T136-K142 PolarHBondContact OG1-NZ 3.24Å; S137-K142 VanDerWaalsContact OG-CG 3.29Å; S137-K142 WeakPolarHBondContact OG-CG 3.5Å; T139-K142 WeakPolarHBondContact O-CB 3.42Å; T139-K142 PolarHBondContact O-N 3.41Å; R140-K142 VanDerWaalsContact C-N 3.26Å; K142-K144 VanDerWaalsContact C-N 3.26Å; K142-K144 PolarHBondContact O-N 3.01Å; K142-G145 PolarHBondContact O-N 2.91Å; K142-G145 VanDerWaalsContact O-N 3.08Å; K142-A146 WeakPolarHBondContact CD-O 3.42Å; K142-A146 WeakPolarHBondContact CE-O 3.4Å; K142-A146 PolarHBondContact NZ-O 3.43Å; K142-G147 VanDerWaalsContact NZ-C 3.31Å; K142-G147 PolarHBondContact NZ-O 3.31Å; K142-G151 WeakPolarHBondContact CE-O 3.41Å; K142-K154 WeakPolarHBondContact O-CE 3.44Å; K142-C204 WeakPolarHBondContact CE-O 3.11Å; K142-C204 PolarHBondContact NZ-O 3.35Å; K142-L205 HydrophobicContact CD-CD1 4.09Å; K142-L205 HydrophobicContact CG-CD1 3.87Å
143T96.9Very high96.6Very high79 Ų7927 Ų2749%0.48516%0.158SC..THydrogen-bonded Turntrans-55.5-38.1177.346.90000113.3G151 P152 K154T143-G151 WeakPolarHBondContact OG1-CA 3.15Å; T143-P152 HydrophobicContact CG2-CG 4.21Å; T143-P152 PolarHBondContact N-O 3.25Å; T143-P152 VanDerWaalsContact OG1-CD 3.26Å; T143-P152 WeakPolarHBondContact OG1-CD 3.38Å; T143-P152 PolarHBondContact OG1-O 2.97Å; T143-K154 HydrophobicContact CG2-CG 4.17Å
144K92.7Very high96.6Very high101 Ų10130.1 Ų30.144%0.43917%0.172SC..THydrogen-bonded Turntrans-78.5-22.1178.3-175.2-179.3168.1-159.50113.9K142 A146 N148 K150K142-K144 VanDerWaalsContact C-N 3.26Å; K142-K144 PolarHBondContact O-N 3.01Å; K144-A146 VanDerWaalsContact C-N 3.28Å; K144-A146 HydrophobicContact CD-CB 4.12Å; K144-A146 HydrophobicContact CG-CB 4.09Å; K144-A146 PolarHBondContact O-N 3.36Å; K144-N148 WeakPolarHBondContact CD-O 3.47Å; K144-N148 PolarHBondContact NZ-O 3.37Å; K144-N148 PolarHBondContact NZ-OD1 2.63Å; K144-K150 WeakPolarHBondContact CB-O 3.34Å; K144-K150 WeakPolarHBondContact CD-O 3.46Å
145G94.8Very high96.5Very high44 Ų4432.1 Ų32.145%0.45419%0.192SC..SBendtrans69.619.9-172.500000114.7T139 K142T139-G145 WeakPolarHBondContact O-CA 3.49Å; K142-G145 PolarHBondContact O-N 2.91Å; K142-G145 VanDerWaalsContact O-N 3.08Å
146A95.3Very high96.5Very high26 Ų2638.7 Ų38.722%0.21522%0.223CC..SBendtrans-136.6151.4-179.100000111.7K142 K144 N148K142-A146 WeakPolarHBondContact CD-O 3.42Å; K142-A146 WeakPolarHBondContact CE-O 3.4Å; K142-A146 PolarHBondContact NZ-O 3.43Å; K144-A146 VanDerWaalsContact C-N 3.28Å; K144-A146 HydrophobicContact CD-CB 4.12Å; K144-A146 HydrophobicContact CG-CB 4.09Å; K144-A146 PolarHBondContact O-N 3.36Å; A146-N148 VanDerWaalsContact C-N 3.33Å; A146-N148 PolarHBondContact O-N 3.01Å
147G93.3Very high96.4Very high21 Ų2138.7 Ų38.722%0.21622%0.223CC..SBendtrans-68.1-28.8-179.700000113.9T136 K142 Q203 C204T136-G147 PolarHBondContact OG1-O 3.14Å; K142-G147 VanDerWaalsContact NZ-C 3.31Å; K142-G147 PolarHBondContact NZ-O 3.31Å; G147-Q203 WeakPolarHBondContact O-CA 3.32Å; G147-C204 PolarHBondContact O-N 3.37Å; G147-C204 VanDerWaalsContact O-N 3.08Å
148N96.3Very high96.3Very high51 Ų5148.2 Ų48.227%0.27326%0.259SS..BIsolated β-bridgetrans-112.5172.7-179.669.1-0.6000113.5K144 A146 P201 F202K144-N148 WeakPolarHBondContact CD-O 3.47Å; K144-N148 PolarHBondContact NZ-O 3.37Å; K144-N148 PolarHBondContact NZ-OD1 2.63Å; A146-N148 VanDerWaalsContact C-N 3.33Å; A146-N148 PolarHBondContact O-N 3.01Å; N148-P201 PolarHBondContact ND2-O 3.36Å; N148-F202 WeakPolarHBondContact CA-O 3.2Å; N148-F202 VanDerWaalsContact CB-C 3.45Å; N148-F202 WeakPolarHBondContact CB-O 3.24Å
149G96.3Very high96.3Very high0 Ų050.1 Ų50.10%027%0.27CS..SBendtrans65.8174.8178.800000114.7G151 Y200G149-G151 PolarHBondContact O-N 3.29Å; G149-G151 VanDerWaalsContact O-N 3.08Å; G149-Y200 WeakPolarHBondContact CA-O 3.48Å; G149-Y200 PolarHBondContact N-O 3.36Å
150K97.4Very high96.4Very high112 Ų11251.6 Ų51.649%0.48727%0.274SS..SBendtrans-49.8115.6-177.6-174.4173-175.9167.40112.9K144 G195 L196 L197K144-K150 WeakPolarHBondContact CB-O 3.34Å; K144-K150 WeakPolarHBondContact CD-O 3.46Å; K150-G195 VanDerWaalsContact CA-O 3.28Å; K150-G195 WeakPolarHBondContact CA-O 3.35Å; K150-L196 WeakPolarHBondContact CD-O 3.21Å; K150-L197 PolarHBondContact N-O 3.33Å
151G96.4Very high96.6Very high0 Ų053.2 Ų53.20%028%0.281CS..  trans-177.485.3-175.600000113.1K142 T143 G149 G195K142-G151 WeakPolarHBondContact CE-O 3.41Å; T143-G151 WeakPolarHBondContact OG1-CA 3.15Å; G149-G151 PolarHBondContact O-N 3.29Å; G149-G151 VanDerWaalsContact O-N 3.08Å; G151-G195 PolarHBondContact N-O 3.07Å
152P97.1Very high96.6Very high33 Ų3353.2 Ų53.221%0.21428%0.281CS..BIsolated β-bridgetrans-66.3171.5168.130.5-37.9000111.5T143 G206T143-P152 HydrophobicContact CG2-CG 4.21Å; T143-P152 PolarHBondContact N-O 3.25Å; T143-P152 VanDerWaalsContact OG1-CD 3.26Å; T143-P152 WeakPolarHBondContact OG1-CD 3.38Å; T143-P152 PolarHBondContact OG1-O 2.97Å; P152-G206 WeakPolarHBondContact CA-O 3.49Å; P152-G206 WeakPolarHBondContact CB-O 3.33Å
153L97.9Very high96.7Very high4 Ų455.6 Ų55.62%0.02129%0.292CS..BIsolated β-bridgetrans-55146.9167.2-69.5175.3000111.3L141 W165 L205 F207L141-L153 HydrophobicContact CB-CD2 3.89Å; L141-L153 CarbonylContact O-C 3.56Å; L141-L153 WeakPolarHBondContact O-CA 3.13Å; L153-W165 HydrophobicContact CD1-CB 4.12Å; L153-W165 HydrophobicContact CD1-CG 4.13Å; L153-W165 HydrophobicContact CD2-CB 4.39Å; L153-W165 HydrophobicContact CD2-CG 4.39Å; L153-L205 HydrophobicContact CD2-CD1 4.02Å; L153-L205 HydrophobicContact CD2-CD2 4.01Å; L153-L205 HydrophobicContact CG-CD1 4.07Å; L153-L205 HydrophobicContact CG-CD2 4.06Å; L153-L205 HydrophobicContact CG-CG 4.43Å; L153-F207 HydrophobicContact CD1-CE1 4.04Å; L153-F207 HydrophobicContact CD1-CZ 3.84Å; L153-F207 HydrophobicContact CG-CZ 4.22Å
154K97.8Very high96.8Very high66 Ų6651.9 Ų51.929%0.28727%0.269SS..SBendtrans-67.3153.1171.4-72.8175.1178166.70110.6R140 L141 K142 T143 Y161 H162R140-K154 WeakPolarHBondContact O-CE 3.19Å; R140-K154 PolarHBondContact O-NZ 3.18Å; L141-K154 PolarHBondContact O-N 3.13Å; K142-K154 WeakPolarHBondContact O-CE 3.44Å; T143-K154 HydrophobicContact CG2-CG 4.17Å; K154-Y161 HydrophobicContact CB-CD1 3.79Å; K154-Y161 HydrophobicContact CB-CD2 3.76Å; K154-Y161 HydrophobicContact CB-CE1 3.87Å; K154-Y161 HydrophobicContact CB-CE2 3.85Å; K154-Y161 HydrophobicContact CB-CG 3.74Å; K154-Y161 HydrophobicContact CD-CD1 4.17Å; K154-Y161 HydrophobicContact CD-CE1 3.6Å; K154-Y161 HydrophobicContact CG-CE1 4.37Å; K154-Y161 WeakPolarHBondContact O-CB 3.45Å; K154-H162 PolarHBondContact O-CE1 2.94Å
155G96.9Very high97Very high42 Ų4247 Ų4743%0.43325%0.248SC..SBendtrans68.3-14017300000113.1D159G155-D159 WeakPolarHBondContact CA-OD2 3Å
156Q97Very high97.2Very high140 Ų14045 Ų4565%0.65423%0.226SC*.  trans-140.7149.9-172.2-64.7-62.8-36.700111.7R158 D159 H162Q156-R158 PolarHBondContact O-N 3.05Å; Q156-D159 PolarHBondContact N-OD2 3.48Å; Q156-D159 WeakPolarHBondContact O-CB 3.29Å; Q156-D159 PolarHBondContact O-N 3.22Å; Q156-H162 VanDerWaalsContact C-ND1 3.25Å; Q156-H162 PolarHBondContact N-CE1 3.23Å; Q156-H162 PolarHBondContact O-ND1 3.45Å; Q156-H162 VanDerWaalsContact O-ND1 3.1Å
157P97.8Very high97.4Very high8 Ų847.4 Ų47.45%0.05223%0.23CC..THydrogen-bonded Turntrans-48.7139.6175.7-31.739000113D214 R218 D219P157-D214 HydrophobicContact CB-CB 3.79Å; P157-D214 HydrophobicContact CG-CB 3.63Å; P157-R218 HydrophobicContact CB-CB 4.47Å; P157-D219 WeakPolarHBondContact CA-OD2 3.48Å
158R95.6Very high97.6Very high199 Ų19946.4 Ų46.475%0.75122%0.22SC*.THydrogen-bonded Turntrans84.6-7.5-166.6-158.8176.5173.8177.9-0.1116.4Q156 R218 D219Q156-R158 PolarHBondContact O-N 3.05Å; R158-R218 HydrophobicContact CB-CB 4.25Å; R158-D219 WeakPolarHBondContact CA-OD1 3.4Å; R158-D219 VanDerWaalsContact N-CG 3.34Å; R158-D219 PolarHBondContact N-OD1 2.98Å; R158-D219 PolarHBondContact N-OD2 3.46Å
159D97.9Very high97.8Very high41 Ų4144 Ų4422%0.21921%0.207CC..SBendtrans-84.9-178.9178.178.67.8000114G155 Q156 Y161 H162 Q163G155-D159 WeakPolarHBondContact CA-OD2 3Å; Q156-D159 PolarHBondContact N-OD2 3.48Å; Q156-D159 WeakPolarHBondContact O-CB 3.29Å; Q156-D159 PolarHBondContact O-N 3.22Å; D159-Y161 VanDerWaalsContact C-N 3.27Å; D159-Y161 PolarHBondContact O-N 2.88Å; D159-Y161 WeakPolarHBondContact OD1-CA 3.25Å; D159-Y161 WeakPolarHBondContact OD1-CB 3.23Å; D159-Y161 PolarHBondContact OD1-N 3.31Å; D159-Y161 WeakPolarHBondContact OD2-CD2 3.33Å; D159-H162 PolarHBondContact O-N 3.44Å; D159-H162 IonicContact OD1-CE1 3.99Å; D159-H162 IonicContact OD1-CG 3.47Å; D159-H162 PolarHBondContact OD1-N 3.26Å; D159-H162 IonicContact OD1-ND1 3.6Å; D159-H162 PolarHBondContact OD1-ND1 3.14Å; D159-H162 IonicContact OD2-ND1 3.61Å; D159-Q163 VanDerWaalsContact O-CB 3.26Å; D159-Q163 WeakPolarHBondContact O-CB 3.41Å; D159-Q163 VanDerWaalsContact O-CG 3.24Å; D159-Q163 WeakPolarHBondContact O-CG 3.45Å; D159-Q163 PolarHBondContact O-N 3.32Å
160I97.7Very high97.9Very high88 Ų8844.9 Ų44.945%0.45121%0.213SC..Hα-helixtrans-60.9-33.2-179.7-165.8172000112.9F98 T164F98-I160 HydrophobicContact CB-CD1 3.93Å; F98-I160 HydrophobicContact CB-CG1 4.23Å; F98-I160 HydrophobicContact CD1-CD1 3.86Å; F98-I160 HydrophobicContact CD1-CG1 3.73Å; F98-I160 HydrophobicContact CD2-CD1 4.16Å; F98-I160 HydrophobicContact CE1-CD1 4.4Å; F98-I160 HydrophobicContact CE1-CG1 4.3Å; F98-I160 HydrophobicContact CE1-CG2 4.25Å; F98-I160 HydrophobicContact CG-CD1 3.72Å; F98-I160 HydrophobicContact CG-CG1 4.06Å; I160-T164 WeakPolarHBondContact O-CB 3.21Å; I160-T164 PolarHBondContact O-N 3.39Å; I160-T164 PolarHBondContact O-OG1 3.24Å
161Y98.3Very high97.9Very high62 Ų6243.8 Ų43.824%0.24321%0.208CC..Hα-helixtrans-72-46.4-177.7-59.9-79.4000110.7F98 L141 K154 D159 T164 W165F98-Y161 AromaticContact CE1-CD1 3.77Å; F98-Y161 HydrophobicContact CE1-CD1 3.77Å; F98-Y161 AromaticContact CE1-CE1 3.75Å; F98-Y161 HydrophobicContact CE1-CE1 3.75Å; F98-Y161 HydrophobicContact CZ-CD1 4.31Å; F98-Y161 AromaticContact CZ-CE1 3.81Å; F98-Y161 HydrophobicContact CZ-CE1 3.81Å; L141-Y161 HydrophobicContact CD2-CD1 3.86Å; K154-Y161 HydrophobicContact CB-CD1 3.79Å; K154-Y161 HydrophobicContact CB-CD2 3.76Å; K154-Y161 HydrophobicContact CB-CE1 3.87Å; K154-Y161 HydrophobicContact CB-CE2 3.85Å; K154-Y161 HydrophobicContact CB-CG 3.74Å; K154-Y161 HydrophobicContact CD-CD1 4.17Å; K154-Y161 HydrophobicContact CD-CE1 3.6Å; K154-Y161 HydrophobicContact CG-CE1 4.37Å; K154-Y161 WeakPolarHBondContact O-CB 3.45Å; D159-Y161 VanDerWaalsContact C-N 3.27Å; D159-Y161 PolarHBondContact O-N 2.88Å; D159-Y161 WeakPolarHBondContact OD1-CA 3.25Å; D159-Y161 WeakPolarHBondContact OD1-CB 3.23Å; D159-Y161 PolarHBondContact OD1-N 3.31Å; D159-Y161 WeakPolarHBondContact OD2-CD2 3.33Å; Y161-T164 PolarHBondContact O-N 2.84Å; Y161-W165 PolarHBondContact O-N 2.86Å
162H98.7Very high98Very high0 Ų043.8 Ų43.80%021%0.208CC..Hα-helixtrans-70.8-42.5-179.2-64.974.9000111.9K154 Q156 D159 T164 W165 A166 H211 F215 D219K154-H162 PolarHBondContact O-CE1 2.94Å; Q156-H162 VanDerWaalsContact C-ND1 3.25Å; Q156-H162 PolarHBondContact N-CE1 3.23Å; Q156-H162 PolarHBondContact O-ND1 3.45Å; Q156-H162 VanDerWaalsContact O-ND1 3.1Å; D159-H162 PolarHBondContact O-N 3.44Å; D159-H162 IonicContact OD1-CE1 3.99Å; D159-H162 IonicContact OD1-CG 3.47Å; D159-H162 PolarHBondContact OD1-N 3.26Å; D159-H162 IonicContact OD1-ND1 3.6Å; D159-H162 PolarHBondContact OD1-ND1 3.14Å; D159-H162 IonicContact OD2-ND1 3.61Å; H162-T164 VanDerWaalsContact C-N 3.31Å; H162-T164 PolarHBondContact O-N 3.08Å; H162-W165 PolarHBondContact O-N 3.14Å; H162-A166 PolarHBondContact O-N 3.05Å; H162-H211 AromaticContact CD2-NE2 3.65Å; H162-H211 AromaticContact CE1-NE2 3.9Å; H162-H211 AromaticContact NE2-CD2 3.83Å; H162-H211 AromaticContact NE2-CE1 3.69Å; H162-H211 AromaticContact NE2-NE2 2.82Å; H162-H211 PolarHBondContact NE2-NE2 3.01Å; H162-F215 HydrophobicContact CB-CD2 4.19Å; H162-F215 HydrophobicContact CB-CE2 4.5Å; H162-F215 AromaticContact CD2-CD2 3.99Å; H162-D219 HydrophobicContact CB-CB 4.27Å; H162-D219 VanDerWaalsContact CB-OD2 3.27Å; H162-D219 WeakPolarHBondContact CB-OD2 3.47Å; H162-D219 IonicContact CG-OD2 2.77Å
163Q98.4Very high98.1Very high51 Ų5142.3 Ų42.324%0.23820%0.198CC..Hα-helixtrans-62.7-38.4173.8-72.6-69.8-25.500111.8D159 A166 R167 R218 D219D159-Q163 VanDerWaalsContact O-CB 3.26Å; D159-Q163 WeakPolarHBondContact O-CB 3.41Å; D159-Q163 VanDerWaalsContact O-CG 3.24Å; D159-Q163 WeakPolarHBondContact O-CG 3.45Å; D159-Q163 PolarHBondContact O-N 3.32Å; Q163-A166 PolarHBondContact O-N 2.88Å; Q163-R167 WeakPolarHBondContact O-CG 3.44Å; Q163-R167 PolarHBondContact O-N 2.95Å; Q163-R167 PolarHBondContact O-NH1 3.27Å; Q163-R218 PolarHBondContact NE2-O 2.91Å; Q163-D219 VanDerWaalsContact CD-OD1 3.26Å; Q163-D219 WeakPolarHBondContact CG-OD1 3.2Å; Q163-D219 PolarHBondContact NE2-OD1 2.88Å
164T98.6Very high98.1Very high0 Ų044.6 Ų44.60%021%0.21CC..Hα-helixtrans-65.4-40.1174.6-59.40000111.2F98 L100 L141 I160 Y161 H162 R167 Y168F98-T164 HydrophobicContact CD1-CG2 4.42Å; F98-T164 PolarHBondContact O-OG1 3.16Å; L100-T164 HydrophobicContact CD1-CG2 4.38Å; L100-T164 HydrophobicContact CD2-CG2 3.93Å; L100-T164 HydrophobicContact CG-CG2 4.11Å; L141-T164 HydrophobicContact CD1-CG2 4.23Å; L141-T164 HydrophobicContact CD2-CG2 4.23Å; I160-T164 WeakPolarHBondContact O-CB 3.21Å; I160-T164 PolarHBondContact O-N 3.39Å; I160-T164 PolarHBondContact O-OG1 3.24Å; Y161-T164 PolarHBondContact O-N 2.84Å; H162-T164 VanDerWaalsContact C-N 3.31Å; H162-T164 PolarHBondContact O-N 3.08Å; T164-R167 PolarHBondContact O-N 2.73Å; T164-R167 PolarHBondContact OG1-NH2 3.11Å; T164-Y168 WeakPolarHBondContact O-CB 3.21Å; T164-Y168 PolarHBondContact O-N 3.45Å
165W98.8Very high98.2Very high0 Ų042 Ų420%020%0.201CC..Hα-helixtrans-65.8-41.9176.2-175.5-129.7000112.7P134 S137 L141 L153 Y161 H162 R167 Y168 I169 L205 F215P134-W165 HydrophobicContact CB-CH2 3.66Å; P134-W165 HydrophobicContact CB-CZ2 3.59Å; P134-W165 HydrophobicContact CG-CH2 4.21Å; P134-W165 HydrophobicContact CG-CZ2 3.65Å; S137-W165 VanDerWaalsContact CA-CZ3 3.47Å; S137-W165 VanDerWaalsContact CB-CE3 3.47Å; L141-W165 HydrophobicContact CD1-CB 4.35Å; L141-W165 HydrophobicContact CD1-CE3 4.44Å; L153-W165 HydrophobicContact CD1-CB 4.12Å; L153-W165 HydrophobicContact CD1-CG 4.13Å; L153-W165 HydrophobicContact CD2-CB 4.39Å; L153-W165 HydrophobicContact CD2-CG 4.39Å; Y161-W165 PolarHBondContact O-N 2.86Å; H162-W165 PolarHBondContact O-N 3.14Å; W165-R167 PolarHBondContact O-N 2.81Å; W165-Y168 AromaticContact CE3-CD1 3.82Å; W165-Y168 HydrophobicContact CE3-CD1 3.82Å; W165-Y168 HydrophobicContact CE3-CE1 4.5Å; W165-Y168 AromaticContact CE3-CG 3.85Å; W165-Y168 HydrophobicContact CE3-CG 3.85Å; W165-Y168 AromaticContact CH2-CD1 3.92Å; W165-Y168 HydrophobicContact CH2-CD1 3.92Å; W165-Y168 AromaticContact CH2-CE1 3.95Å; W165-Y168 HydrophobicContact CH2-CE1 3.95Å; W165-Y168 AromaticContact CZ3-CD1 3.22Å; W165-Y168 HydrophobicContact CZ3-CD1 3.22Å; W165-Y168 HydrophobicContact CZ3-CD2 4.25Å; W165-Y168 AromaticContact CZ3-CE1 3.51Å; W165-Y168 HydrophobicContact CZ3-CE1 3.51Å; W165-Y168 HydrophobicContact CZ3-CE2 4.46Å; W165-Y168 AromaticContact CZ3-CG 3.64Å; W165-Y168 HydrophobicContact CZ3-CG 3.64Å; W165-Y168 WeakPolarHBondContact O-CB 3.5Å; W165-Y168 PolarHBondContact O-N 3.3Å; W165-I169 PolarHBondContact O-N 2.98Å; W165-L205 HydrophobicContact CZ2-CD2 4.15Å; W165-F215 HydrophobicContact CB-CE2 4.49Å; W165-F215 AromaticContact CD1-CE1 3.86Å; W165-F215 AromaticContact CD1-CE2 3.82Å; W165-F215 AromaticContact CD1-CZ 3.27Å; W165-F215 HydrophobicContact CG-CZ 4.18Å; W165-F215 AromaticContact NE1-CZ 3.94Å
166A98.7Very high98.3Very high0 Ų040 Ų400%018%0.181CC..Hα-helixtrans-61-43.7173.400000112.1H162 Q163 Y168 I169 V170 F215 D219 L220 T223H162-A166 PolarHBondContact O-N 3.05Å; Q163-A166 PolarHBondContact O-N 2.88Å; A166-Y168 VanDerWaalsContact C-N 3.31Å; A166-Y168 PolarHBondContact O-N 3.43Å; A166-I169 PolarHBondContact O-N 3.42Å; A166-V170 PolarHBondContact O-N 2.91Å; A166-F215 HydrophobicContact CB-CE2 4.25Å; A166-D219 HydrophobicContact CB-CB 4.1Å; A166-L220 HydrophobicContact CB-CD1 4.48Å; A166-T223 HydrophobicContact CB-CG2 4.07Å
167R98.6Very high98.3Very high77 Ų7735.3 Ų35.329%0.29117%0.166SC..Hα-helixtrans-65.2-31.8174.4-72.4-166.3-54.3-79.2-0.6113.2F98 L100 Q163 T164 W165 I169 V170 K171 T223F98-R167 PolarHBondContact O-NH2 3.34Å; L100-R167 HydrophobicContact CD1-CB 3.88Å; Q163-R167 WeakPolarHBondContact O-CG 3.44Å; Q163-R167 PolarHBondContact O-N 2.95Å; Q163-R167 PolarHBondContact O-NH1 3.27Å; T164-R167 PolarHBondContact O-N 2.73Å; T164-R167 PolarHBondContact OG1-NH2 3.11Å; W165-R167 PolarHBondContact O-N 2.81Å; R167-I169 VanDerWaalsContact C-N 3.29Å; R167-I169 PolarHBondContact O-N 3.32Å; R167-V170 PolarHBondContact O-N 3.42Å; R167-K171 WeakPolarHBondContact O-CB 3.15Å; R167-K171 WeakPolarHBondContact O-CG 3.28Å; R167-K171 PolarHBondContact O-N 3Å; R167-T223 HydrophobicContact CG-CG2 4.24Å
168Y98.7Very high98.4Very high0 Ų042.5 Ų42.50%020%0.199CC..Hα-helixtrans-60.9-41174.8179-78.4000111.1M79 Y91 A92 L100 F103 P138 T164 W165 A166 K171 F172M79-Y168 HydrophobicContact CE-CD1 4.42Å; M79-Y168 HydrophobicContact CE-CE1 4.36Å; Y91-Y168 WeakPolarHBondContact CB-OH 3.35Å; Y91-Y168 AromaticContact CD2-CE1 3.81Å; Y91-Y168 HydrophobicContact CD2-CE1 3.81Å; Y91-Y168 HydrophobicContact CD2-CE2 4.31Å; Y91-Y168 AromaticContact CD2-CZ 3.48Å; Y91-Y168 VanDerWaalsContact CD2-CZ 3.48Å; Y91-Y168 WeakPolarHBondContact CD2-OH 3.26Å; Y91-Y168 HydrophobicContact CE2-CE1 4.48Å; Y91-Y168 HydrophobicContact CG-CE2 4.48Å; Y91-Y168 AromaticContact CG-CZ 3.94Å; Y91-Y168 VanDerWaalsContact CG-OH 3.31Å; Y91-Y168 PolarHBondContact N-OH 2.9Å; A92-Y168 HydrophobicContact CB-CD2 4.07Å; A92-Y168 HydrophobicContact CB-CE2 3.91Å; L100-Y168 HydrophobicContact CD2-CD2 4.29Å; F103-Y168 AromaticContact CD2-CD2 3.84Å; F103-Y168 HydrophobicContact CD2-CD2 3.84Å; F103-Y168 HydrophobicContact CD2-CE2 4Å; F103-Y168 HydrophobicContact CD2-CG 4.46Å; F103-Y168 HydrophobicContact CE2-CD1 4.31Å; F103-Y168 AromaticContact CE2-CD2 3.71Å; F103-Y168 HydrophobicContact CE2-CD2 3.71Å; F103-Y168 HydrophobicContact CE2-CE1 4.31Å; F103-Y168 AromaticContact CE2-CE2 3.73Å; F103-Y168 HydrophobicContact CE2-CE2 3.73Å; F103-Y168 HydrophobicContact CE2-CG 4.03Å; P138-Y168 HydrophobicContact CG-CD2 4.14Å; P138-Y168 HydrophobicContact CG-CE2 3.9Å; T164-Y168 WeakPolarHBondContact O-CB 3.21Å; T164-Y168 PolarHBondContact O-N 3.45Å; W165-Y168 AromaticContact CE3-CD1 3.82Å; W165-Y168 HydrophobicContact CE3-CD1 3.82Å; W165-Y168 HydrophobicContact CE3-CE1 4.5Å; W165-Y168 AromaticContact CE3-CG 3.85Å; W165-Y168 HydrophobicContact CE3-CG 3.85Å; W165-Y168 AromaticContact CH2-CD1 3.92Å; W165-Y168 HydrophobicContact CH2-CD1 3.92Å; W165-Y168 AromaticContact CH2-CE1 3.95Å; W165-Y168 HydrophobicContact CH2-CE1 3.95Å; W165-Y168 AromaticContact CZ3-CD1 3.22Å; W165-Y168 HydrophobicContact CZ3-CD1 3.22Å; W165-Y168 HydrophobicContact CZ3-CD2 4.25Å; W165-Y168 AromaticContact CZ3-CE1 3.51Å; W165-Y168 HydrophobicContact CZ3-CE1 3.51Å; W165-Y168 HydrophobicContact CZ3-CE2 4.46Å; W165-Y168 AromaticContact CZ3-CG 3.64Å; W165-Y168 HydrophobicContact CZ3-CG 3.64Å; W165-Y168 WeakPolarHBondContact O-CB 3.5Å; W165-Y168 PolarHBondContact O-N 3.3Å; A166-Y168 VanDerWaalsContact C-N 3.31Å; A166-Y168 PolarHBondContact O-N 3.43Å; Y168-K171 PolarHBondContact O-N 3.32Å; Y168-F172 PolarHBondContact O-N 3Å
169I98.8Very high98.5Very high0 Ų036.3 Ų36.30%018%0.178CC..Hα-helixtrans-64.7-41.9176-65.6165.6000110.8M79 W165 A166 R167 F172 L173 L220 L224M79-I169 HydrophobicContact CE-CB 4.14Å; M79-I169 HydrophobicContact CE-CG1 3.8Å; M79-I169 HydrophobicContact CE-CG2 4.18Å; W165-I169 PolarHBondContact O-N 2.98Å; A166-I169 PolarHBondContact O-N 3.42Å; R167-I169 VanDerWaalsContact C-N 3.29Å; R167-I169 PolarHBondContact O-N 3.32Å; I169-F172 WeakPolarHBondContact O-CB 3.46Å; I169-F172 PolarHBondContact O-N 3.48Å; I169-L173 WeakPolarHBondContact O-CG 3.35Å; I169-L173 PolarHBondContact O-N 2.94Å; I169-L220 HydrophobicContact CB-CD1 4.23Å; I169-L220 HydrophobicContact CD1-CD1 3.6Å; I169-L220 HydrophobicContact CD1-CD2 4.16Å; I169-L220 HydrophobicContact CG1-CD1 4.5Å; I169-L220 HydrophobicContact CG2-CD1 4.22Å; I169-L224 HydrophobicContact CG2-CD2 4.48Å
170V98.5Very high98.5Very high20 Ų2043.1 Ų43.112%0.12121%0.206CC..Hα-helixtrans-63.8-43.9174.61750000111.8A166 R167 F172 L173 D174 T223 L224A166-V170 PolarHBondContact O-N 2.91Å; R167-V170 PolarHBondContact O-N 3.42Å; V170-F172 VanDerWaalsContact C-N 3.27Å; V170-F172 PolarHBondContact O-N 2.81Å; V170-L173 WeakPolarHBondContact O-CB 3.45Å; V170-L173 PolarHBondContact O-N 2.81Å; V170-D174 PolarHBondContact O-N 2.97Å; V170-T223 HydrophobicContact CG2-CG2 3.65Å; V170-L224 HydrophobicContact CG2-CD2 4.14Å
171K98.5Very high98.5Very high88 Ų8839 Ų3938%0.38319%0.185SC..Hα-helixtrans-60-35.6176.3-79.5-72.3-171.8177.50112.8L100 F103 R167 Y168 A175L100-K171 HydrophobicContact CB-CG 4.48Å; L100-K171 HydrophobicContact CD1-CG 4.14Å; F103-K171 HydrophobicContact CD1-CB 3.93Å; F103-K171 HydrophobicContact CD2-CB 3.72Å; F103-K171 HydrophobicContact CD2-CG 4.45Å; F103-K171 HydrophobicContact CE1-CB 3.95Å; F103-K171 WeakPolarHBondContact CE1-O 3.45Å; F103-K171 HydrophobicContact CE2-CB 3.71Å; F103-K171 HydrophobicContact CG-CB 3.84Å; F103-K171 HydrophobicContact CG-CG 4.38Å; F103-K171 HydrophobicContact CZ-CB 3.85Å; R167-K171 WeakPolarHBondContact O-CB 3.15Å; R167-K171 WeakPolarHBondContact O-CG 3.28Å; R167-K171 PolarHBondContact O-N 3Å; Y168-K171 PolarHBondContact O-N 3.32Å; K171-A175 WeakPolarHBondContact O-CB 3.35Å; K171-A175 PolarHBondContact O-N 2.87Å
172F98.8Very high98.5Very high0 Ų044.1 Ų44.10%021%0.211CC..Hα-helixtrans-62.9-46.3171.9162.9-99.2000112M79 Y91 F103 A132 Y168 I169 V170 A175 Y176 F183M79-F172 HydrophobicContact CE-CB 3.62Å; M79-F172 HydrophobicContact CE-CD1 3.51Å; M79-F172 HydrophobicContact CE-CD2 4.35Å; M79-F172 HydrophobicContact CE-CE1 4.25Å; M79-F172 HydrophobicContact CE-CG 3.56Å; M79-F172 HydrophobicContact CG-CD1 4.02Å; M79-F172 HydrophobicContact CG-CD2 4.24Å; M79-F172 HydrophobicContact CG-CE1 3.83Å; M79-F172 HydrophobicContact CG-CE2 4.02Å; M79-F172 HydrophobicContact CG-CG 4.21Å; M79-F172 HydrophobicContact CG-CZ 3.8Å; M79-F172 HydrophobicContact SD-CD1 4.02Å; M79-F172 HydrophobicContact SD-CE1 4.18Å; M79-F172 HydrophobicContact SD-CG 4.46Å; Y91-F172 HydrophobicContact CD2-CD2 4.33Å; Y91-F172 HydrophobicContact CE2-CB 4.35Å; Y91-F172 AromaticContact CE2-CD2 3.43Å; Y91-F172 HydrophobicContact CE2-CD2 3.43Å; Y91-F172 VanDerWaalsContact CE2-CD2 3.43Å; Y91-F172 HydrophobicContact CE2-CE2 4.11Å; Y91-F172 HydrophobicContact CE2-CG 4.25Å; Y91-F172 AromaticContact CZ-CD2 3.98Å; F103-F172 HydrophobicContact CZ-CB 4.01Å; A132-F172 HydrophobicContact CB-CE1 3.54Å; A132-F172 HydrophobicContact CB-CZ 3.78Å; Y168-F172 PolarHBondContact O-N 3Å; I169-F172 WeakPolarHBondContact O-CB 3.46Å; I169-F172 PolarHBondContact O-N 3.48Å; V170-F172 VanDerWaalsContact C-N 3.27Å; V170-F172 PolarHBondContact O-N 2.81Å; F172-A175 PolarHBondContact O-N 3.12Å; F172-Y176 AromaticContact CD2-CD2 3.8Å; F172-Y176 HydrophobicContact CD2-CD2 3.8Å; F172-Y176 AromaticContact CD2-CE2 3.85Å; F172-Y176 HydrophobicContact CD2-CE2 3.85Å; F172-Y176 AromaticContact CE2-CD2 3.47Å; F172-Y176 HydrophobicContact CE2-CD2 3.47Å; F172-Y176 VanDerWaalsContact CE2-CD2 3.47Å; F172-Y176 AromaticContact CE2-CE2 3.26Å; F172-Y176 HydrophobicContact CE2-CE2 3.26Å; F172-Y176 HydrophobicContact CE2-CG 4.24Å; F172-Y176 AromaticContact CE2-CZ 3.86Å; F172-Y176 HydrophobicContact CZ-CD2 4.04Å; F172-Y176 HydrophobicContact CZ-CE2 4.04Å; F172-Y176 HydrophobicContact CZ-CG 4.39Å; F172-Y176 PolarHBondContact O-N 3.05Å; F172-F183 HydrophobicContact CE1-CD2 4.23Å; F172-F183 HydrophobicContact CE1-CE1 4.15Å; F172-F183 AromaticContact CE1-CE2 3.68Å; F172-F183 HydrophobicContact CE1-CE2 3.68Å; F172-F183 AromaticContact CE1-CZ 3.66Å; F172-F183 HydrophobicContact CE1-CZ 3.66Å; F172-F183 HydrophobicContact CZ-CE1 4.09Å; F172-F183 AromaticContact CZ-CE2 3.76Å; F172-F183 HydrophobicContact CZ-CE2 3.76Å; F172-F183 AromaticContact CZ-CZ 3.4Å; F172-F183 HydrophobicContact CZ-CZ 3.4Å
173L98.8Very high98.5Very high2 Ų245 Ų451%0.0122%0.215CC..Hα-helixtrans-64.2-40.7177.5-64171.6000111.5I169 V170 A177 F183 V186 L224 H229 V232I169-L173 WeakPolarHBondContact O-CG 3.35Å; I169-L173 PolarHBondContact O-N 2.94Å; V170-L173 WeakPolarHBondContact O-CB 3.45Å; V170-L173 PolarHBondContact O-N 2.81Å; L173-A177 VanDerWaalsContact O-CB 3.27Å; L173-A177 WeakPolarHBondContact O-CB 3.36Å; L173-A177 PolarHBondContact O-N 2.97Å; L173-F183 HydrophobicContact CD2-CB 3.83Å; L173-F183 HydrophobicContact CD2-CD2 3.54Å; L173-F183 HydrophobicContact CD2-CE2 4.37Å; L173-F183 HydrophobicContact CD2-CG 3.81Å; L173-V186 HydrophobicContact CD2-CG1 4.12Å; L173-L224 HydrophobicContact CD1-CD2 3.76Å; L173-H229 HydrophobicContact CB-CB 4.36Å; L173-H229 HydrophobicContact CD1-CB 3.76Å; L173-H229 PolarHBondContact O-CE1 3.03Å; L173-V232 HydrophobicContact CD1-CG1 4.46Å; L173-V232 HydrophobicContact CD1-CG2 4.27Å; L173-V232 HydrophobicContact CD2-CG2 4.49Å
174D98.6Very high98.5Very high53 Ų5345.5 Ų45.528%0.28321%0.214SC..Hα-helixtrans-57.4-51.4172.9-69.9-28.4000110.9V170 Y176 A177 E178 H229V170-D174 PolarHBondContact O-N 2.97Å; D174-Y176 PolarHBondContact O-N 3.22Å; D174-A177 WeakPolarHBondContact O-CB 3.44Å; D174-A177 PolarHBondContact O-N 3.12Å; D174-A177 VanDerWaalsContact O-N 3.11Å; D174-E178 PolarHBondContact O-N 3.35Å; D174-H229 PolarHBondContact N-NE2 2.92Å; D174-H229 IonicContact OD1-CD2 3.19Å; D174-H229 PolarHBondContact OD1-CD2 2.75Å; D174-H229 IonicContact OD1-CE1 3.94Å; D174-H229 IonicContact OD1-NE2 3.1Å; D174-H229 PolarHBondContact OD1-NE2 3.05Å
175A98.7Very high98.4Very high12 Ų1245.5 Ų45.510%0.09921%0.214CC..Hα-helixtrans-63.8-41.7-176.700000112F103 L105 K171 F172 A177 E178 H179F103-A175 HydrophobicContact CE1-CB 4.07Å; L105-A175 HydrophobicContact CD1-CB 3.64Å; L105-A175 HydrophobicContact CD2-CB 4.23Å; L105-A175 HydrophobicContact CG-CB 3.76Å; K171-A175 WeakPolarHBondContact O-CB 3.35Å; K171-A175 PolarHBondContact O-N 2.87Å; F172-A175 PolarHBondContact O-N 3.12Å; A175-A177 VanDerWaalsContact C-N 3.33Å; A175-A177 PolarHBondContact O-N 2.99Å; A175-E178 WeakPolarHBondContact O-CB 3.45Å; A175-E178 PolarHBondContact O-N 2.79Å; A175-H179 PolarHBondContact O-CD2 2.63Å; A175-H179 VanDerWaalsContact O-CD2 3.27Å; A175-H179 PolarHBondContact O-N 3.05Å
176Y98.6Very high98.5Very high0 Ų045.5 Ų45.50%021%0.214CC..Hα-helixtrans-68.6-31.5174.7-92.4-113.4000112.8V77 L105 D109 K113 I114 I117 F172 D174 H179 K180 L181 F183V77-Y176 HydrophobicContact CG1-CE1 4.07Å; L105-Y176 HydrophobicContact CD1-CD2 3.76Å; L105-Y176 HydrophobicContact CD1-CE2 3.79Å; L105-Y176 HydrophobicContact CD2-CD2 4.25Å; L105-Y176 HydrophobicContact CD2-CE2 3.92Å; D109-Y176 WeakPolarHBondContact OD1-CE2 3.38Å; D109-Y176 PolarHBondContact OD1-OH 2.98Å; K113-Y176 VanDerWaalsContact CE-OH 3.24Å; K113-Y176 WeakPolarHBondContact CE-OH 3.41Å; K113-Y176 PolarHBondContact NZ-OH 2.98Å; I114-Y176 HydrophobicContact CD1-CE1 4.33Å; I114-Y176 HydrophobicContact CD1-CE2 4.24Å; I114-Y176 HydrophobicContact CG1-CD1 4.24Å; I114-Y176 HydrophobicContact CG1-CE1 3.77Å; I114-Y176 HydrophobicContact CG1-CE2 4.5Å; I117-Y176 HydrophobicContact CD1-CE1 4.11Å; F172-Y176 AromaticContact CD2-CD2 3.8Å; F172-Y176 HydrophobicContact CD2-CD2 3.8Å; F172-Y176 AromaticContact CD2-CE2 3.85Å; F172-Y176 HydrophobicContact CD2-CE2 3.85Å; F172-Y176 AromaticContact CE2-CD2 3.47Å; F172-Y176 HydrophobicContact CE2-CD2 3.47Å; F172-Y176 VanDerWaalsContact CE2-CD2 3.47Å; F172-Y176 AromaticContact CE2-CE2 3.26Å; F172-Y176 HydrophobicContact CE2-CE2 3.26Å; F172-Y176 HydrophobicContact CE2-CG 4.24Å; F172-Y176 AromaticContact CE2-CZ 3.86Å; F172-Y176 HydrophobicContact CZ-CD2 4.04Å; F172-Y176 HydrophobicContact CZ-CE2 4.04Å; F172-Y176 HydrophobicContact CZ-CG 4.39Å; F172-Y176 PolarHBondContact O-N 3.05Å; D174-Y176 PolarHBondContact O-N 3.22Å; Y176-H179 CarbonylContact O-C 3.5Å; Y176-H179 WeakPolarHBondContact O-CA 3.17Å; Y176-H179 WeakPolarHBondContact O-CB 2.98Å; Y176-H179 PolarHBondContact O-N 3.48Å; Y176-H179 VanDerWaalsContact O-N 3.11Å; Y176-K180 PolarHBondContact O-N 2.98Å; Y176-L181 CarbonylContact C-O 3.52Å; Y176-L181 HydrophobicContact CD1-CB 4.11Å; Y176-L181 HydrophobicContact CD1-CD1 3.76Å; Y176-L181 HydrophobicContact CE1-CD1 4.08Å; Y176-L181 PolarHBondContact O-N 2.93Å; Y176-F183 AromaticContact CD1-CE2 3.56Å; Y176-F183 HydrophobicContact CD1-CE2 3.56Å; Y176-F183 AromaticContact CD1-CZ 3.69Å; Y176-F183 HydrophobicContact CD1-CZ 3.69Å; Y176-F183 HydrophobicContact CE1-CE2 4.37Å; Y176-F183 HydrophobicContact CE1-CZ 4.05Å; Y176-F183 AromaticContact CG-CE2 3.69Å; Y176-F183 HydrophobicContact CG-CE2 3.69Å; Y176-F183 HydrophobicContact CG-CZ 4.16Å
177A98.4Very high98.5Very high41 Ų4145.5 Ų45.534%0.33921%0.214SC..Hα-helixtrans-67.2-34.3174.300000112.4L173 D174 A175 H179 K180 L181L173-A177 VanDerWaalsContact O-CB 3.27Å; L173-A177 WeakPolarHBondContact O-CB 3.36Å; L173-A177 PolarHBondContact O-N 2.97Å; D174-A177 WeakPolarHBondContact O-CB 3.44Å; D174-A177 PolarHBondContact O-N 3.12Å; D174-A177 VanDerWaalsContact O-N 3.11Å; A175-A177 VanDerWaalsContact C-N 3.33Å; A175-A177 PolarHBondContact O-N 2.99Å; A177-H179 PolarHBondContact O-N 2.99Å; A177-K180 WeakPolarHBondContact O-CA 3.08Å; A177-K180 PolarHBondContact O-N 3.31Å; A177-L181 WeakPolarHBondContact CA-O 3.47Å; A177-L181 PolarHBondContact N-O 2.72Å
178E98.5Very high98.5Very high159 Ų15941.9 Ų41.974%0.74320%0.201SC*.Hα-helixtrans-59.4-32.1170.2-68.4175.3-173.200111.7D174 A175 K180D174-E178 PolarHBondContact O-N 3.35Å; A175-E178 WeakPolarHBondContact O-CB 3.45Å; A175-E178 PolarHBondContact O-N 2.79Å; E178-K180 VanDerWaalsContact C-N 3.26Å; E178-K180 PolarHBondContact O-N 3.15Å
179H98.3Very high98.5Very high69 Ų6941.9 Ų41.932%0.31920%0.201SC..THydrogen-bonded Turntrans-86.314.4171.8-70.9-83.2000114.1I114 H118 A175 Y176 A177 L181I114-H179 HydrophobicContact CD1-CB 4.07Å; I114-H179 HydrophobicContact CG2-CB 3.76Å; H118-H179 PolarHBondContact CE1-O 2.99Å; H118-H179 VanDerWaalsContact CE1-O 3.25Å; H118-H179 PolarHBondContact NE2-O 2.87Å; A175-H179 PolarHBondContact O-CD2 2.63Å; A175-H179 VanDerWaalsContact O-CD2 3.27Å; A175-H179 PolarHBondContact O-N 3.05Å; Y176-H179 CarbonylContact O-C 3.5Å; Y176-H179 WeakPolarHBondContact O-CA 3.17Å; Y176-H179 WeakPolarHBondContact O-CB 2.98Å; Y176-H179 PolarHBondContact O-N 3.48Å; Y176-H179 VanDerWaalsContact O-N 3.11Å; A177-H179 PolarHBondContact O-N 2.99Å; H179-L181 VanDerWaalsContact C-N 3.27Å; H179-L181 PolarHBondContact O-N 3.45Å
180K98.4Very high98.5Very high184 Ų18442 Ų4280%0.820%0.202SC*.THydrogen-bonded Turntrans60.530.1178.3-51.5178.3-178.61780114.1Y176 A177 E178Y176-K180 PolarHBondContact O-N 2.98Å; A177-K180 WeakPolarHBondContact O-CA 3.08Å; A177-K180 PolarHBondContact O-N 3.31Å; E178-K180 VanDerWaalsContact C-N 3.26Å; E178-K180 PolarHBondContact O-N 3.15Å
181L97.9Very high98.5Very high2 Ų242.1 Ų42.11%0.0120%0.201CC..  trans-109.4133.3173.2-64.7177.6000109.7I114 I117 H118 L121 L130 Y176 A177 H179I114-L181 HydrophobicContact CB-CD1 4.29Å; I114-L181 HydrophobicContact CG1-CD1 4.01Å; I114-L181 HydrophobicContact CG2-CD1 4.07Å; I117-L181 HydrophobicContact CB-CD1 4.08Å; I117-L181 HydrophobicContact CB-CD2 4.44Å; I117-L181 HydrophobicContact CD1-CD1 4.05Å; I117-L181 HydrophobicContact CG2-CD1 3.9Å; I117-L181 HydrophobicContact CG2-CD2 3.59Å; I117-L181 HydrophobicContact CG2-CG 4.4Å; H118-L181 VanDerWaalsContact CE1-CD2 3.46Å; H118-L181 WeakPolarHBondContact CE1-CD2 3.24Å; L121-L181 HydrophobicContact CD1-CD2 3.58Å; L130-L181 HydrophobicContact CD1-CB 3.98Å; L130-L181 HydrophobicContact CD1-CD2 4.27Å; Y176-L181 CarbonylContact C-O 3.52Å; Y176-L181 HydrophobicContact CD1-CB 4.11Å; Y176-L181 HydrophobicContact CD1-CD1 3.76Å; Y176-L181 HydrophobicContact CE1-CD1 4.08Å; Y176-L181 PolarHBondContact O-N 2.93Å; A177-L181 WeakPolarHBondContact CA-O 3.47Å; A177-L181 PolarHBondContact N-O 2.72Å; H179-L181 VanDerWaalsContact C-N 3.27Å; H179-L181 PolarHBondContact O-N 3.45Å
182Q97.6Very high98.5Very high168 Ų16838 Ų3879%0.78518%0.183SC*.  trans-118.1137.7178.7-69.5-173.4-23.400110.1
183F98.1Very high98.4Very high19 Ų1939.6 Ų39.68%0.08319%0.194CC..EExtended strand (participates in β ladder)trans-90.9138.5177.8-75.5-91.7000111.4V77 L130 A132 F172 L173 Y176 V232V77-F183 HydrophobicContact CB-CE1 3.99Å; V77-F183 HydrophobicContact CB-CZ 4.23Å; V77-F183 HydrophobicContact CG1-CZ 4.38Å; V77-F183 HydrophobicContact CG2-CE1 4.07Å; V77-F183 HydrophobicContact CG2-CZ 4.35Å; L130-F183 HydrophobicContact CB-CD1 3.55Å; L130-F183 HydrophobicContact CB-CE1 3.66Å; L130-F183 HydrophobicContact CB-CG 4.16Å; L130-F183 HydrophobicContact CB-CZ 4.38Å; L130-F183 HydrophobicContact CD1-CZ 4.45Å; A132-F183 HydrophobicContact CB-CD1 3.74Å; A132-F183 HydrophobicContact CB-CE1 3.43Å; A132-F183 VanDerWaalsContact CB-CE1 3.43Å; A132-F183 HydrophobicContact CB-CZ 4.15Å; F172-F183 HydrophobicContact CE1-CD2 4.23Å; F172-F183 HydrophobicContact CE1-CE1 4.15Å; F172-F183 AromaticContact CE1-CE2 3.68Å; F172-F183 HydrophobicContact CE1-CE2 3.68Å; F172-F183 AromaticContact CE1-CZ 3.66Å; F172-F183 HydrophobicContact CE1-CZ 3.66Å; F172-F183 HydrophobicContact CZ-CE1 4.09Å; F172-F183 AromaticContact CZ-CE2 3.76Å; F172-F183 HydrophobicContact CZ-CE2 3.76Å; F172-F183 AromaticContact CZ-CZ 3.4Å; F172-F183 HydrophobicContact CZ-CZ 3.4Å; L173-F183 HydrophobicContact CD2-CB 3.83Å; L173-F183 HydrophobicContact CD2-CD2 3.54Å; L173-F183 HydrophobicContact CD2-CE2 4.37Å; L173-F183 HydrophobicContact CD2-CG 3.81Å; Y176-F183 AromaticContact CD1-CE2 3.56Å; Y176-F183 HydrophobicContact CD1-CE2 3.56Å; Y176-F183 AromaticContact CD1-CZ 3.69Å; Y176-F183 HydrophobicContact CD1-CZ 3.69Å; Y176-F183 HydrophobicContact CE1-CE2 4.37Å; Y176-F183 HydrophobicContact CE1-CZ 4.05Å; Y176-F183 AromaticContact CG-CE2 3.69Å; Y176-F183 HydrophobicContact CG-CE2 3.69Å; Y176-F183 HydrophobicContact CG-CZ 4.16Å; F183-V232 HydrophobicContact CB-CG1 4.31Å; F183-V232 HydrophobicContact CB-CG2 4.39Å
184W98.1Very high98.4Very high62 Ų6239.6 Ų39.624%0.23520%0.195CC..EExtended strand (participates in β ladder)trans-75.5-45166.1159.159.4000110L130 L131 R233 M291 F293L130-W184 PolarHBondContact O-N 3.4Å; L131-W184 HydrophobicContact CB-CE3 4.3Å; L131-W184 HydrophobicContact CB-CZ3 4.4Å; L131-W184 HydrophobicContact CD2-CZ3 4.44Å; W184-R233 WeakPolarHBondContact O-CG 3.37Å; W184-R233 PolarHBondContact O-N 3.19Å; W184-M291 HydrophobicContact CH2-CE 3.83Å; W184-M291 HydrophobicContact CZ2-CE 3.49Å; W184-M291 VanDerWaalsContact CZ2-CE 3.49Å; W184-F293 AromaticContact CH2-CD2 3.95Å; W184-F293 HydrophobicContact CH2-CD2 3.95Å; W184-F293 AromaticContact CH2-CE2 3.85Å; W184-F293 HydrophobicContact CH2-CE2 3.85Å; W184-F293 HydrophobicContact CH2-CG 4.35Å; W184-F293 HydrophobicContact CH2-CZ 4.18Å; W184-F293 HydrophobicContact CZ3-CE1 4.37Å; W184-F293 HydrophobicContact CZ3-CE2 4.13Å; W184-F293 HydrophobicContact CZ3-CZ 4.02Å
185A98.4Very high98.3Very high0 Ų037.1 Ų37.10%018%0.181CC..EExtended strand (participates in β ladder)trans-149.6159.5-173.800000112.7L130 L131 A132 R233 L235L130-A185 PolarHBondContact O-N 2.96Å; L131-A185 WeakPolarHBondContact CA-O 3.32Å; L131-A185 HydrophobicContact CD1-CB 3.66Å; A132-A185 PolarHBondContact N-O 3.4Å; A132-A185 VanDerWaalsContact N-O 3.1Å; A185-R233 CarbonylContact C-O 3.56Å; A185-R233 WeakPolarHBondContact CA-O 3.08Å; A185-R233 HydrophobicContact CB-CB 3.94Å; A185-L235 HydrophobicContact CB-CD1 4.47Å; A185-L235 HydrophobicContact CB-CG 4.31Å
186V98.8Very high98.3Very high0 Ų039.3 Ų39.30%019%0.191CC..EExtended strand (participates in β ladder)trans-125.8152.6163.5-640000109.4A132 L173 L224 V232 R233 L234 L235A132-V186 HydrophobicContact CB-CG1 4.24Å; A132-V186 CarbonylContact O-C 3.59Å; A132-V186 WeakPolarHBondContact O-CA 3.36Å; L173-V186 HydrophobicContact CD2-CG1 4.12Å; V186-L224 HydrophobicContact CG2-CD1 4.25Å; V186-V232 HydrophobicContact CG1-CG1 4.02Å; V186-V232 HydrophobicContact CG2-CG1 4.27Å; V186-R233 PolarHBondContact N-O 3.11Å; V186-L234 HydrophobicContact CG2-CD1 4.02Å; V186-L234 WeakPolarHBondContact O-CA 3.48Å; V186-L235 PolarHBondContact O-N 3.39Å
187T98.9Very high98.2Very high0 Ų044.2 Ų44.20%022%0.216CC..EExtended strand (participates in β ladder)trans-96.1154.9165.6820000110.4L131 A132 S133 E189 L235 D238 A265L131-T187 HydrophobicContact CD1-CG2 3.85Å; A132-T187 PolarHBondContact O-N 3.48Å; S133-T187 WeakPolarHBondContact CB-OG1 3.47Å; S133-T187 VanDerWaalsContact OG-CG2 3.28Å; S133-T187 WeakPolarHBondContact OG-CG2 3.39Å; S133-T187 PolarHBondContact OG-OG1 3.01Å; T187-E189 VanDerWaalsContact C-N 3.31Å; T187-E189 PolarHBondContact O-N 2.66Å; T187-L235 CarbonylContact C-O 3.5Å; T187-L235 VanDerWaalsContact CA-O 3.28Å; T187-L235 WeakPolarHBondContact CA-O 3.49Å; T187-L235 HydrophobicContact CG2-CB 4.16Å; T187-D238 VanDerWaalsContact CB-OD2 3.22Å; T187-D238 WeakPolarHBondContact CB-OD2 3.5Å; T187-D238 HydrophobicContact CG2-CB 3.99Å; T187-D238 VanDerWaalsContact CG2-CG 3.47Å; T187-D238 VanDerWaalsContact CG2-OD2 3.25Å; T187-D238 WeakPolarHBondContact CG2-OD2 3.38Å; T187-D238 PolarHBondContact OG1-OD2 3.24Å; T187-A265 HydrophobicContact CG2-CB 4.26Å
188A98.7Very high98Very high1 Ų147.1 Ų47.11%0.00824%0.235CC..SBendtrans-66.9-32.9-177.800000113Q212 I216 L220 L234 L235A188-Q212 HydrophobicContact CB-CG 4.11Å; A188-I216 HydrophobicContact CB-CD1 4.24Å; A188-I216 HydrophobicContact CB-CG1 4.48Å; A188-L220 HydrophobicContact CB-CD2 4.37Å; A188-L234 HydrophobicContact CB-CD1 4.28Å; A188-L235 PolarHBondContact N-O 3.46Å
189E98.8Very high97.8Very high0 Ų042.7 Ų42.70%023%0.232CC..  trans-174.2139.9177.817759.1-156.200108.1W135 T187 P192 L205 F207 D238W135-E189 WeakPolarHBondContact CA-OE1 3.15Å; T187-E189 VanDerWaalsContact C-N 3.31Å; T187-E189 PolarHBondContact O-N 2.66Å; E189-P192 HydrophobicContact CB-CB 4.28Å; E189-P192 HydrophobicContact CG-CB 4.14Å; E189-P192 WeakPolarHBondContact O-CD 3.21Å; E189-L205 HydrophobicContact CG-CB 4.29Å; E189-L205 WeakPolarHBondContact CG-O 3.24Å; E189-L205 VanDerWaalsContact OE1-CB 3.31Å; E189-L205 WeakPolarHBondContact OE1-CB 3.22Å; E189-L205 PolarHBondContact OE1-N 2.71Å; E189-F207 HydrophobicContact CB-CD2 4.03Å; E189-F207 HydrophobicContact CB-CE2 3.95Å; E189-F207 HydrophobicContact CG-CD2 3.97Å; E189-F207 HydrophobicContact CG-CE2 3.95Å; E189-D238 WeakPolarHBondContact O-CB 3.37Å
190N98.6Very high97.7Very high3 Ų341 Ų412%0.01622%0.222CC..SBendtrans-74.3123.9170178.999.7000110.5P134 W135P134-N190 WeakPolarHBondContact O-CB 3.36Å; P134-N190 PolarHBondContact O-N 3.04Å; W135-N190 VanDerWaalsContact CD1-ND2 3.26Å; W135-N190 HydrophobicContact CD2-CB 4.18Å; W135-N190 HydrophobicContact CG-CB 4.15Å; W135-N190 PolarHBondContact NE1-ND2 3.18Å
191E98.3Very high97.6Very high22 Ų2235.5 Ų35.510%0.10321%0.206CC..SBendtrans46.558178.6-60.2-165.9167.300114S193 A194 Y200 D238 D239 Q240 H267E191-S193 PolarHBondContact O-N 3.09Å; E191-A194 HydrophobicContact CB-CB 4.02Å; E191-A194 WeakPolarHBondContact O-CB 3.29Å; E191-A194 PolarHBondContact O-N 3.19Å; E191-Y200 PolarHBondContact OE2-OH 3.44Å; E191-Y200 VanDerWaalsContact OE2-OH 3.08Å; E191-D238 WeakPolarHBondContact CA-O 3.39Å; E191-D238 PolarHBondContact N-O 3.14Å; E191-D239 VanDerWaalsContact C-OD2 3.28Å; E191-D239 WeakPolarHBondContact CA-OD2 3.45Å; E191-Q240 PolarHBondContact OE1-NE2 3.32Å; E191-H267 IonicContact OE1-CE1 3.52Å; E191-H267 IonicContact OE1-ND1 3.68Å; E191-H267 PolarHBondContact OE1-ND1 2.77Å
192P98.5Very high97.6Very high0 Ų036.3 Ų36.30%021%0.209CC..THydrogen-bonded Turntrans-54.3-25.4-178.720.7-34.6000113.9E189 A194 G206 F207 L237 D239 W247E189-P192 HydrophobicContact CB-CB 4.28Å; E189-P192 HydrophobicContact CG-CB 4.14Å; E189-P192 WeakPolarHBondContact O-CD 3.21Å; P192-A194 VanDerWaalsContact C-N 3.34Å; P192-G206 WeakPolarHBondContact O-CA 3.38Å; P192-F207 HydrophobicContact CB-CB 3.88Å; P192-F207 HydrophobicContact CB-CD2 4.14Å; P192-F207 PolarHBondContact O-N 2.96Å; P192-L237 WeakPolarHBondContact CD-O 3.45Å; P192-L237 VanDerWaalsContact CG-O 3.25Å; P192-L237 WeakPolarHBondContact CG-O 3.36Å; P192-D239 HydrophobicContact CG-CB 4.47Å; P192-W247 HydrophobicContact CB-CH2 3.86Å; P192-W247 HydrophobicContact CB-CZ2 4.12Å; P192-W247 HydrophobicContact CG-CH2 3.38Å; P192-W247 HydrophobicContact CG-CZ2 3.82Å; P192-W247 HydrophobicContact CG-CZ3 4.1Å
193S98.4Very high97.6Very high35 Ų3528.4 Ų28.425%0.24517%0.173CC..THydrogen-bonded Turntrans-70.9-28.1175.972.60000113.1E191 G195 L196 D239E191-S193 PolarHBondContact O-N 3.09Å; S193-G195 VanDerWaalsContact C-N 3.33Å; S193-G195 PolarHBondContact O-N 2.65Å; S193-L196 VanDerWaalsContact O-CB 3.32Å; S193-L196 WeakPolarHBondContact O-CB 3.22Å; S193-L196 PolarHBondContact O-N 2.9Å; S193-D239 WeakPolarHBondContact CB-OD2 3.29Å; S193-D239 PolarHBondContact N-OD2 3.28Å; S193-D239 PolarHBondContact OG-OD1 2.8Å; S193-D239 PolarHBondContact OG-OD2 3.36Å
194A97.3Very high97.6Very high2 Ų227.6 Ų27.62%0.01717%0.169CC..G310 helixtrans-60.4-41.6179.200000112.1E191 P192 L196 L197 Y200 C204E191-A194 HydrophobicContact CB-CB 4.02Å; E191-A194 WeakPolarHBondContact O-CB 3.29Å; E191-A194 PolarHBondContact O-N 3.19Å; P192-A194 VanDerWaalsContact C-N 3.34Å; A194-L196 PolarHBondContact O-N 3.01Å; A194-L196 VanDerWaalsContact O-N 3.09Å; A194-L197 WeakPolarHBondContact O-CB 3.2Å; A194-L197 PolarHBondContact O-N 3.18Å; A194-Y200 HydrophobicContact CB-CD1 4.16Å; A194-Y200 HydrophobicContact CB-CD2 3.88Å; A194-Y200 HydrophobicContact CB-CE1 3.77Å; A194-Y200 HydrophobicContact CB-CE2 3.45Å; A194-Y200 VanDerWaalsContact CB-CE2 3.45Å; A194-Y200 HydrophobicContact CB-CG 4.19Å; A194-C204 HydrophobicContact CB-CB 4.08Å
195G97.4Very high97.6Very high0 Ų024.7 Ų24.70%016%0.158CC..G310 helixtrans-71.31.2177.600000114.8K150 G151 S193 G206K150-G195 VanDerWaalsContact CA-O 3.28Å; K150-G195 WeakPolarHBondContact CA-O 3.35Å; G151-G195 PolarHBondContact N-O 3.07Å; S193-G195 VanDerWaalsContact C-N 3.33Å; S193-G195 PolarHBondContact O-N 2.65Å; G195-G206 VanDerWaalsContact C-CA 3.42Å; G195-G206 VanDerWaalsContact CA-CA 3.48Å
196L97.6Very high97.6Very high59 Ų5924.7 Ų24.731%0.30916%0.158SC..G310 helixtrans-93.8-12.3169.4-54.6-179.9000112.6K150 S193 A194 T208K150-L196 WeakPolarHBondContact CD-O 3.21Å; S193-L196 VanDerWaalsContact O-CB 3.32Å; S193-L196 WeakPolarHBondContact O-CB 3.22Å; S193-L196 PolarHBondContact O-N 2.9Å; A194-L196 PolarHBondContact O-N 3.01Å; A194-L196 VanDerWaalsContact O-N 3.09Å; L196-T208 HydrophobicContact CD1-CG2 4.29Å; L196-T208 HydrophobicContact CD2-CG2 4.38Å
197L96.4Very high97.6Very high102 Ų10224.7 Ų24.753%0.53416%0.158SC..SBendtrans-88.8125.3-178.3-59.2177000111.7K150 A194 G199 Y200K150-L197 PolarHBondContact N-O 3.33Å; A194-L197 WeakPolarHBondContact O-CB 3.2Å; A194-L197 PolarHBondContact O-N 3.18Å; L197-G199 PolarHBondContact O-N 3.18Å; L197-Y200 HydrophobicContact CD1-CD2 4.29Å; L197-Y200 PolarHBondContact O-N 3.28Å
198S94.8Very high97.6Very high103 Ų10327.3 Ų27.372%0.7217%0.174SC*.THydrogen-bonded Turntrans-64.1130.8173.1-65.40000110Y200S198-Y200 VanDerWaalsContact C-N 3.34Å; S198-Y200 PolarHBondContact O-N 3.01Å
199G94.2Very high97.6Very high66 Ų6627.9 Ų27.968%0.6818%0.178SC*.THydrogen-bonded Turntrans76.612.1178.400000115.7L197L197-G199 PolarHBondContact O-N 3.18Å
200Y97.3Very high97.6Very high32 Ų3231.5 Ų31.513%0.12520%0.195CC..  trans-53.4128.7173-166.7-96.8000110.9G149 E191 A194 L197 S198 F202 C204G149-Y200 WeakPolarHBondContact CA-O 3.48Å; G149-Y200 PolarHBondContact N-O 3.36Å; E191-Y200 PolarHBondContact OE2-OH 3.44Å; E191-Y200 VanDerWaalsContact OE2-OH 3.08Å; A194-Y200 HydrophobicContact CB-CD1 4.16Å; A194-Y200 HydrophobicContact CB-CD2 3.88Å; A194-Y200 HydrophobicContact CB-CE1 3.77Å; A194-Y200 HydrophobicContact CB-CE2 3.45Å; A194-Y200 VanDerWaalsContact CB-CE2 3.45Å; A194-Y200 HydrophobicContact CB-CG 4.19Å; L197-Y200 HydrophobicContact CD1-CD2 4.29Å; L197-Y200 PolarHBondContact O-N 3.28Å; S198-Y200 VanDerWaalsContact C-N 3.34Å; S198-Y200 PolarHBondContact O-N 3.01Å; Y200-F202 HydrophobicContact CD1-CD2 4.4Å; Y200-F202 WeakPolarHBondContact CD1-O 3.36Å; Y200-F202 HydrophobicContact CE1-CD1 4.2Å; Y200-F202 AromaticContact CE1-CD2 3.5Å; Y200-F202 HydrophobicContact CE1-CD2 3.5Å; Y200-F202 HydrophobicContact CE1-CE1 4.03Å; Y200-F202 AromaticContact CE1-CE2 3.31Å; Y200-F202 HydrophobicContact CE1-CE2 3.31Å; Y200-F202 AromaticContact CE1-CG 3.97Å; Y200-F202 HydrophobicContact CE1-CG 3.97Å; Y200-F202 AromaticContact CE1-CZ 3.6Å; Y200-F202 HydrophobicContact CE1-CZ 3.6Å; Y200-F202 HydrophobicContact CE2-CZ 4.41Å; Y200-F202 AromaticContact CZ-CE1 3.98Å; Y200-F202 AromaticContact CZ-CE2 3.5Å; Y200-F202 AromaticContact CZ-CZ 3.39Å; Y200-F202 PolarHBondContact O-N 2.59Å; Y200-F202 WeakPolarHBondContact OH-CE2 3.35Å; Y200-F202 WeakPolarHBondContact OH-CZ 3.45Å; Y200-C204 HydrophobicContact CD1-CB 3.75Å; Y200-C204 VanDerWaalsContact CD1-SG 3.59Å; Y200-C204 HydrophobicContact CE1-CB 3.9Å
201P96.2Very high97.7Very high70 Ų7032.9 Ų32.946%0.45520%0.201SC..  trans-77.4-27.3-157.622.1-28.2000115.1N148N148-P201 PolarHBondContact ND2-O 3.36Å
202F96.8Very high97.7Very high18 Ų1831.9 Ų31.98%0.07920%0.196CC..SBendtrans-128-174.5-174.352.7-97.4000113D83 N148 Y200 C204 W349 V350D83-F202 HydrophobicContact CB-CB 3.86Å; D83-F202 HydrophobicContact CB-CD1 3.99Å; D83-F202 HydrophobicContact CB-CD2 3.78Å; D83-F202 HydrophobicContact CB-CE1 4.45Å; D83-F202 HydrophobicContact CB-CE2 4.24Å; D83-F202 HydrophobicContact CB-CG 3.62Å; N148-F202 WeakPolarHBondContact CA-O 3.2Å; N148-F202 VanDerWaalsContact CB-C 3.45Å; N148-F202 WeakPolarHBondContact CB-O 3.24Å; Y200-F202 HydrophobicContact CD1-CD2 4.4Å; Y200-F202 WeakPolarHBondContact CD1-O 3.36Å; Y200-F202 HydrophobicContact CE1-CD1 4.2Å; Y200-F202 AromaticContact CE1-CD2 3.5Å; Y200-F202 HydrophobicContact CE1-CD2 3.5Å; Y200-F202 HydrophobicContact CE1-CE1 4.03Å; Y200-F202 AromaticContact CE1-CE2 3.31Å; Y200-F202 HydrophobicContact CE1-CE2 3.31Å; Y200-F202 AromaticContact CE1-CG 3.97Å; Y200-F202 HydrophobicContact CE1-CG 3.97Å; Y200-F202 AromaticContact CE1-CZ 3.6Å; Y200-F202 HydrophobicContact CE1-CZ 3.6Å; Y200-F202 HydrophobicContact CE2-CZ 4.41Å; Y200-F202 AromaticContact CZ-CE1 3.98Å; Y200-F202 AromaticContact CZ-CE2 3.5Å; Y200-F202 AromaticContact CZ-CZ 3.39Å; Y200-F202 PolarHBondContact O-N 2.59Å; Y200-F202 WeakPolarHBondContact OH-CE2 3.35Å; Y200-F202 WeakPolarHBondContact OH-CZ 3.45Å; F202-C204 PolarHBondContact O-N 2.71Å; F202-W349 HydrophobicContact CB-CZ2 3.97Å; F202-V350 HydrophobicContact CB-CG1 4.09Å; F202-V350 HydrophobicContact CB-CG2 3.96Å; F202-V350 HydrophobicContact CD1-CG2 3.89Å; F202-V350 HydrophobicContact CG-CG2 4.3Å
203Q98.3Very high97.7Very high3 Ų334.8 Ų34.81%0.01421%0.207CC..BIsolated β-bridgetrans-49.8124-176.7-66.892.2-42.700111.1S81 C82 W135 T136 G147S81-Q203 VanDerWaalsContact CB-NE2 3.3Å; S81-Q203 PolarHBondContact OG-NE2 3.49Å; C82-Q203 VanDerWaalsContact C-CD 3.5Å; C82-Q203 VanDerWaalsContact C-NE2 3.32Å; C82-Q203 VanDerWaalsContact C-OE1 3.31Å; C82-Q203 PolarHBondContact O-NE2 3.42Å; C82-Q203 PolarHBondContact O-OE1 2.67Å; W135-Q203 HydrophobicContact CB-CB 3.64Å; W135-Q203 HydrophobicContact CG-CB 4.37Å; W135-Q203 CarbonylContact O-C 3.55Å; T136-Q203 HydrophobicContact CG2-CB 4.08Å; T136-Q203 HydrophobicContact CG2-CG 3.95Å; G147-Q203 WeakPolarHBondContact O-CA 3.32Å
204C98.4Very high97.7Very high2 Ų234.2 Ų34.21%0.01420%0.201CC..  trans-154.3153.4174.860.70000110.6W135 T136 K142 G147 A194 Y200 F202W135-C204 CarbonylContact O-C 2.86Å; W135-C204 WeakPolarHBondContact O-CA 3.3Å; W135-C204 PolarHBondContact O-N 2.95Å; W135-C204 VanDerWaalsContact O-N 3.12Å; T136-C204 PolarHBondContact OG1-O 3.49Å; T136-C204 VanDerWaalsContact OG1-O 3.04Å; K142-C204 WeakPolarHBondContact CE-O 3.11Å; K142-C204 PolarHBondContact NZ-O 3.35Å; G147-C204 PolarHBondContact O-N 3.37Å; G147-C204 VanDerWaalsContact O-N 3.08Å; A194-C204 HydrophobicContact CB-CB 4.08Å; Y200-C204 HydrophobicContact CD1-CB 3.75Å; Y200-C204 VanDerWaalsContact CD1-SG 3.59Å; Y200-C204 HydrophobicContact CE1-CB 3.9Å; F202-C204 PolarHBondContact O-N 2.71Å
205L98.7Very high97.8Very high0 Ų034.1 Ų34.10%020%0.201CC..  trans-131.1120.3168.2-178.264.3000109.7W135 K142 L153 W165 E189 F207W135-L205 PolarHBondContact O-N 2.67Å; K142-L205 HydrophobicContact CD-CD1 4.09Å; K142-L205 HydrophobicContact CG-CD1 3.87Å; L153-L205 HydrophobicContact CD2-CD1 4.02Å; L153-L205 HydrophobicContact CD2-CD2 4.01Å; L153-L205 HydrophobicContact CG-CD1 4.07Å; L153-L205 HydrophobicContact CG-CD2 4.06Å; L153-L205 HydrophobicContact CG-CG 4.43Å; W165-L205 HydrophobicContact CZ2-CD2 4.15Å; E189-L205 HydrophobicContact CG-CB 4.29Å; E189-L205 WeakPolarHBondContact CG-O 3.24Å; E189-L205 VanDerWaalsContact OE1-CB 3.31Å; E189-L205 WeakPolarHBondContact OE1-CB 3.22Å; E189-L205 PolarHBondContact OE1-N 2.71Å; L205-F207 HydrophobicContact CB-CE2 4.27Å; L205-F207 HydrophobicContact CD2-CE2 3.59Å; L205-F207 HydrophobicContact CD2-CZ 3.8Å; L205-F207 HydrophobicContact CG-CD2 4.38Å; L205-F207 HydrophobicContact CG-CE2 3.58Å; L205-F207 HydrophobicContact CG-CZ 4.08Å
206G98.4Very high97.9Very high0 Ų034.1 Ų34.10%020%0.201CC..BIsolated β-bridgetrans-78.5130.1-170.400000113.2P152 P192 G195P152-G206 WeakPolarHBondContact CA-O 3.49Å; P152-G206 WeakPolarHBondContact CB-O 3.33Å; P192-G206 WeakPolarHBondContact O-CA 3.38Å; G195-G206 VanDerWaalsContact C-CA 3.42Å; G195-G206 VanDerWaalsContact CA-CA 3.48Å
207F98.7Very high97.9Very high1 Ų132 Ų320%0.00419%0.191CC..  trans-134.5133.3165.8-63.9-93.3000110.9L153 E189 P192 L205 H211 Q212 F215L153-F207 HydrophobicContact CD1-CE1 4.04Å; L153-F207 HydrophobicContact CD1-CZ 3.84Å; L153-F207 HydrophobicContact CG-CZ 4.22Å; E189-F207 HydrophobicContact CB-CD2 4.03Å; E189-F207 HydrophobicContact CB-CE2 3.95Å; E189-F207 HydrophobicContact CG-CD2 3.97Å; E189-F207 HydrophobicContact CG-CE2 3.95Å; P192-F207 HydrophobicContact CB-CB 3.88Å; P192-F207 HydrophobicContact CB-CD2 4.14Å; P192-F207 PolarHBondContact O-N 2.96Å; L205-F207 HydrophobicContact CB-CE2 4.27Å; L205-F207 HydrophobicContact CD2-CE2 3.59Å; L205-F207 HydrophobicContact CD2-CZ 3.8Å; L205-F207 HydrophobicContact CG-CD2 4.38Å; L205-F207 HydrophobicContact CG-CE2 3.58Å; L205-F207 HydrophobicContact CG-CZ 4.08Å; F207-H211 HydrophobicContact CB-CB 4.45Å; F207-H211 HydrophobicContact CD1-CB 4.17Å; F207-H211 AromaticContact CD1-CD2 3.77Å; F207-H211 AromaticContact CD1-CE1 3.95Å; F207-H211 AromaticContact CD1-CG 3.64Å; F207-H211 AromaticContact CD1-ND1 3.78Å; F207-H211 AromaticContact CD1-NE2 3.94Å; F207-H211 AromaticContact CE1-NE2 3.87Å; F207-Q212 HydrophobicContact CB-CB 4.16Å; F207-F215 HydrophobicContact CE1-CB 4.31Å; F207-F215 HydrophobicContact CE1-CD1 4.15Å; F207-F215 HydrophobicContact CE1-CG 4.24Å; F207-F215 HydrophobicContact CZ-CD1 4.34Å
208T98.8Very high98Very high54 Ų5432.4 Ų32.433%0.33119%0.186SC..  trans-74.2162.2158.581.40000108.8L196 E210 H211 Q212L196-T208 HydrophobicContact CD1-CG2 4.29Å; L196-T208 HydrophobicContact CD2-CG2 4.38Å; T208-E210 WeakPolarHBondContact CB-OE2 3.06Å; T208-E210 PolarHBondContact O-N 3.32Å; T208-E210 PolarHBondContact OG1-N 2.8Å; T208-E210 PolarHBondContact OG1-OE2 3.13Å; T208-H211 PolarHBondContact O-N 3.18Å; T208-H211 VanDerWaalsContact O-N 3.11Å; T208-H211 PolarHBondContact OG1-N 2.97Å; T208-Q212 PolarHBondContact O-N 3.48Å
209P98.8Very high98.2Very high14 Ų1427.5 Ų27.59%0.09115%0.152CC..Hα-helixtrans-60.2-33.2177.519.7-27.3000113R213 W247 V250P209-R213 WeakPolarHBondContact O-CB 3.01Å; P209-R213 PolarHBondContact O-N 3.43Å; P209-W247 HydrophobicContact CB-CD2 3.82Å; P209-W247 HydrophobicContact CB-CG 3.79Å; P209-W247 HydrophobicContact CB-CZ2 4.29Å; P209-W247 HydrophobicContact CG-CG 4.42Å; P209-V250 HydrophobicContact CB-CB 3.79Å; P209-V250 HydrophobicContact CB-CG1 3.75Å; P209-V250 HydrophobicContact CB-CG2 4.16Å; P209-V250 HydrophobicContact CG-CB 4.38Å; P209-V250 HydrophobicContact CG-CG1 4.31Å; P209-V250 HydrophobicContact CG-CG2 4.22Å
210E98.9Very high98.5Very high76 Ų7624.4 Ų24.436%0.35512%0.119SC..Hα-helixtrans-68.4-39.4175.3-56.972.2-157.900111.6T208 R213 D214 V250T208-E210 WeakPolarHBondContact CB-OE2 3.06Å; T208-E210 PolarHBondContact O-N 3.32Å; T208-E210 PolarHBondContact OG1-N 2.8Å; T208-E210 PolarHBondContact OG1-OE2 3.13Å; E210-R213 WeakPolarHBondContact O-CB 3.28Å; E210-R213 PolarHBondContact O-N 3.48Å; E210-D214 WeakPolarHBondContact O-CB 3.47Å; E210-D214 PolarHBondContact O-N 3.35Å; E210-V250 HydrophobicContact CB-CG1 4.46Å; E210-V250 HydrophobicContact CG-CG1 3.91Å
211H98.8Very high98.5Very high31 Ų3123 Ų2314%0.14412%0.115CC..Hα-helixtrans-66.8-44.1176.3-168.1177.4000110.5H162 F207 T208 D214 F215H162-H211 AromaticContact CD2-NE2 3.65Å; H162-H211 AromaticContact CE1-NE2 3.9Å; H162-H211 AromaticContact NE2-CD2 3.83Å; H162-H211 AromaticContact NE2-CE1 3.69Å; H162-H211 AromaticContact NE2-NE2 2.82Å; H162-H211 PolarHBondContact NE2-NE2 3.01Å; F207-H211 HydrophobicContact CB-CB 4.45Å; F207-H211 HydrophobicContact CD1-CB 4.17Å; F207-H211 AromaticContact CD1-CD2 3.77Å; F207-H211 AromaticContact CD1-CE1 3.95Å; F207-H211 AromaticContact CD1-CG 3.64Å; F207-H211 AromaticContact CD1-ND1 3.78Å; F207-H211 AromaticContact CD1-NE2 3.94Å; F207-H211 AromaticContact CE1-NE2 3.87Å; T208-H211 PolarHBondContact O-N 3.18Å; T208-H211 VanDerWaalsContact O-N 3.11Å; T208-H211 PolarHBondContact OG1-N 2.97Å; H211-D214 PolarHBondContact O-N 3.36Å; H211-F215 VanDerWaalsContact O-CB 3.29Å; H211-F215 WeakPolarHBondContact O-CB 3.31Å; H211-F215 PolarHBondContact O-N 2.9Å
212Q98.9Very high98.6Very high1 Ų121 Ų211%0.00510%0.102CC..Hα-helixtrans-63.1-43.6175.1-166.3-176.894.100111.4A188 F207 T208 D214 F215 I216 W247A188-Q212 HydrophobicContact CB-CG 4.11Å; F207-Q212 HydrophobicContact CB-CB 4.16Å; T208-Q212 PolarHBondContact O-N 3.48Å; Q212-D214 PolarHBondContact O-N 2.8Å; Q212-F215 PolarHBondContact O-N 3Å; Q212-I216 HydrophobicContact CG-CD1 3.79Å; Q212-I216 HydrophobicContact CG-CG1 4.2Å; Q212-I216 WeakPolarHBondContact O-CB 3.38Å; Q212-I216 VanDerWaalsContact O-CG1 3.25Å; Q212-I216 WeakPolarHBondContact O-CG1 3.25Å; Q212-I216 PolarHBondContact O-N 2.94Å; Q212-W247 HydrophobicContact CB-CH2 3.6Å; Q212-W247 HydrophobicContact CB-CZ2 4.35Å; Q212-W247 HydrophobicContact CB-CZ3 4.06Å; Q212-W247 HydrophobicContact CG-CH2 4Å; Q212-W247 HydrophobicContact CG-CZ3 4.15Å
213R98.9Very high98.7Very high61 Ų6121.3 Ų21.323%0.2311%0.105CC..Hα-helixtrans-52.6-54.3174.4178.7-16271.1-160.2-2.3111.3P209 E210 I216 A217 V250 V251 D254 A257P209-R213 WeakPolarHBondContact O-CB 3.01Å; P209-R213 PolarHBondContact O-N 3.43Å; E210-R213 WeakPolarHBondContact O-CB 3.28Å; E210-R213 PolarHBondContact O-N 3.48Å; R213-I216 PolarHBondContact O-N 3.28Å; R213-A217 WeakPolarHBondContact O-CB 3.21Å; R213-A217 PolarHBondContact O-N 2.91Å; R213-V250 VanDerWaalsContact CD-O 3.31Å; R213-V250 WeakPolarHBondContact CD-O 3.32Å; R213-V251 HydrophobicContact CB-CB 4.41Å; R213-V251 HydrophobicContact CB-CG1 4.49Å; R213-V251 HydrophobicContact CB-CG2 4.04Å; R213-D254 WeakPolarHBondContact CD-OD2 3.48Å; R213-D254 HydrophobicContact CG-CB 3.95Å; R213-D254 IonicContact NE-OD2 3.79Å; R213-A257 HydrophobicContact CG-CB 3.79Å
214D98.9Very high98.7Very high23 Ų2321.6 Ų21.612%0.12311%0.107CC..Hα-helixtrans-67.8-37.4-175.6-78.610.6000111.6P157 E210 H211 Q212 A217 R218P157-D214 HydrophobicContact CB-CB 3.79Å; P157-D214 HydrophobicContact CG-CB 3.63Å; E210-D214 WeakPolarHBondContact O-CB 3.47Å; E210-D214 PolarHBondContact O-N 3.35Å; H211-D214 PolarHBondContact O-N 3.36Å; Q212-D214 PolarHBondContact O-N 2.8Å; D214-A217 PolarHBondContact O-N 3.43Å; D214-R218 VanDerWaalsContact O-CB 3.23Å; D214-R218 WeakPolarHBondContact O-CB 3.4Å; D214-R218 WeakPolarHBondContact O-CG 3.13Å; D214-R218 PolarHBondContact O-N 3.32Å; D214-R218 IonicContact OD1-NH2 3.73Å; D214-R218 IonicContact OD2-CZ 3.35Å; D214-R218 IonicContact OD2-NH1 3.53Å; D214-R218 PolarHBondContact OD2-NH1 3.14Å; D214-R218 IonicContact OD2-NH2 2.91Å; D214-R218 PolarHBondContact OD2-NH2 2.75Å
215F98.9Very high98.7Very high1 Ų123.7 Ų23.70%0.00412%0.124CC..Hα-helixtrans-62.9-44.1173.8172.8-121.1000111.8H162 W165 A166 F207 H211 Q212 D219 L220H162-F215 HydrophobicContact CB-CD2 4.19Å; H162-F215 HydrophobicContact CB-CE2 4.5Å; H162-F215 AromaticContact CD2-CD2 3.99Å; W165-F215 HydrophobicContact CB-CE2 4.49Å; W165-F215 AromaticContact CD1-CE1 3.86Å; W165-F215 AromaticContact CD1-CE2 3.82Å; W165-F215 AromaticContact CD1-CZ 3.27Å; W165-F215 HydrophobicContact CG-CZ 4.18Å; W165-F215 AromaticContact NE1-CZ 3.94Å; A166-F215 HydrophobicContact CB-CE2 4.25Å; F207-F215 HydrophobicContact CE1-CB 4.31Å; F207-F215 HydrophobicContact CE1-CD1 4.15Å; F207-F215 HydrophobicContact CE1-CG 4.24Å; F207-F215 HydrophobicContact CZ-CD1 4.34Å; H211-F215 VanDerWaalsContact O-CB 3.29Å; H211-F215 WeakPolarHBondContact O-CB 3.31Å; H211-F215 PolarHBondContact O-N 2.9Å; Q212-F215 PolarHBondContact O-N 3Å; F215-D219 HydrophobicContact CD2-CB 3.7Å; F215-D219 HydrophobicContact CE2-CB 3.82Å; F215-D219 CarbonylContact O-C 3.59Å; F215-D219 WeakPolarHBondContact O-CA 3.35Å; F215-D219 WeakPolarHBondContact O-CB 3.23Å; F215-D219 PolarHBondContact O-N 3.32Å; F215-L220 HydrophobicContact CD1-CB 4.29Å; F215-L220 HydrophobicContact CD1-CD2 4.49Å; F215-L220 HydrophobicContact CE1-CB 3.8Å; F215-L220 HydrophobicContact CE1-CD2 3.74Å; F215-L220 HydrophobicContact CE1-CG 4.32Å; F215-L220 HydrophobicContact CE2-CB 4.19Å; F215-L220 HydrophobicContact CZ-CB 3.72Å; F215-L220 HydrophobicContact CZ-CD2 4.23Å; F215-L220 HydrophobicContact CZ-CG 4.38Å; F215-L220 PolarHBondContact O-N 2.83Å
216I98.9Very high98.5Very high0 Ų030.6 Ų30.60%016%0.161CC..Iπ-helixtrans-62.7-50.4175.8-69.3173.7000110.5A188 Q212 R213 R218 G221 P222 L234 M236 V251 A257 V261A188-I216 HydrophobicContact CB-CD1 4.24Å; A188-I216 HydrophobicContact CB-CG1 4.48Å; Q212-I216 HydrophobicContact CG-CD1 3.79Å; Q212-I216 HydrophobicContact CG-CG1 4.2Å; Q212-I216 WeakPolarHBondContact O-CB 3.38Å; Q212-I216 VanDerWaalsContact O-CG1 3.25Å; Q212-I216 WeakPolarHBondContact O-CG1 3.25Å; Q212-I216 PolarHBondContact O-N 2.94Å; R213-I216 PolarHBondContact O-N 3.28Å; I216-R218 PolarHBondContact O-N 2.78Å; I216-G221 WeakPolarHBondContact O-CA 3.34Å; I216-G221 PolarHBondContact O-N 2.96Å; I216-P222 WeakPolarHBondContact O-CD 3.4Å; I216-L234 HydrophobicContact CD1-CD2 4.37Å; I216-L234 HydrophobicContact CG1-CD2 4.12Å; I216-L234 HydrophobicContact CG2-CD2 3.86Å; I216-M236 HydrophobicContact CD1-CB 4.22Å; I216-V251 HydrophobicContact CD1-CG1 4.36Å; I216-A257 HydrophobicContact CG2-CB 4.33Å; I216-V261 HydrophobicContact CD1-CG2 4.1Å; I216-V261 HydrophobicContact CG2-CG2 4.02Å
217A98.8Very high98.1Very high13 Ų1331.7 Ų31.711%0.10717%0.172CC..Iπ-helixtrans-65.2-40.7-175.500000113.1R213 D214 P222 E256 A257R213-A217 WeakPolarHBondContact O-CB 3.21Å; R213-A217 PolarHBondContact O-N 2.91Å; D214-A217 PolarHBondContact O-N 3.43Å; A217-P222 WeakPolarHBondContact O-CD 3.27Å; A217-P222 WeakPolarHBondContact O-CG 3.32Å; A217-E256 HydrophobicContact CB-CB 4.12Å; A217-A257 HydrophobicContact CB-CB 4.07Å
218R98.8Very high97.9Very high112 Ų11237 Ų3742%0.42321%0.205SC..Iπ-helixtrans-99.7-25.7-168.8-59.8-178.2-173154.415.2114.1P157 R158 Q163 D214 I216P157-R218 HydrophobicContact CB-CB 4.47Å; R158-R218 HydrophobicContact CB-CB 4.25Å; Q163-R218 PolarHBondContact NE2-O 2.91Å; D214-R218 VanDerWaalsContact O-CB 3.23Å; D214-R218 WeakPolarHBondContact O-CB 3.4Å; D214-R218 WeakPolarHBondContact O-CG 3.13Å; D214-R218 PolarHBondContact O-N 3.32Å; D214-R218 IonicContact OD1-NH2 3.73Å; D214-R218 IonicContact OD2-CZ 3.35Å; D214-R218 IonicContact OD2-NH1 3.53Å; D214-R218 PolarHBondContact OD2-NH1 3.14Å; D214-R218 IonicContact OD2-NH2 2.91Å; D214-R218 PolarHBondContact OD2-NH2 2.75Å; I216-R218 PolarHBondContact O-N 2.78Å
219D98.8Very high97.8Very high0 Ų035.8 Ų35.80%020%0.195CC..Iπ-helixtrans-126.1-69.5-170-53.9-70.7000111.8P157 R158 H162 Q163 A166 F215 T223P157-D219 WeakPolarHBondContact CA-OD2 3.48Å; R158-D219 WeakPolarHBondContact CA-OD1 3.4Å; R158-D219 VanDerWaalsContact N-CG 3.34Å; R158-D219 PolarHBondContact N-OD1 2.98Å; R158-D219 PolarHBondContact N-OD2 3.46Å; H162-D219 HydrophobicContact CB-CB 4.27Å; H162-D219 VanDerWaalsContact CB-OD2 3.27Å; H162-D219 WeakPolarHBondContact CB-OD2 3.47Å; H162-D219 IonicContact CG-OD2 2.77Å; Q163-D219 VanDerWaalsContact CD-OD1 3.26Å; Q163-D219 WeakPolarHBondContact CG-OD1 3.2Å; Q163-D219 PolarHBondContact NE2-OD1 2.88Å; A166-D219 HydrophobicContact CB-CB 4.1Å; F215-D219 HydrophobicContact CD2-CB 3.7Å; F215-D219 HydrophobicContact CE2-CB 3.82Å; F215-D219 CarbonylContact O-C 3.59Å; F215-D219 WeakPolarHBondContact O-CA 3.35Å; F215-D219 WeakPolarHBondContact O-CB 3.23Å; F215-D219 PolarHBondContact O-N 3.32Å; D219-T223 WeakPolarHBondContact O-CB 3.33Å; D219-T223 PolarHBondContact O-N 2.77Å; D219-T223 PolarHBondContact O-OG1 2.95Å
220L98.8Very high97.7Very high0 Ų040.2 Ų40.20%021%0.214CC..Iπ-helixtrans-65.7-49.4-169.8-177.856.5000112.8A166 I169 A188 F215 T223 L224 L234A166-L220 HydrophobicContact CB-CD1 4.48Å; I169-L220 HydrophobicContact CB-CD1 4.23Å; I169-L220 HydrophobicContact CD1-CD1 3.6Å; I169-L220 HydrophobicContact CD1-CD2 4.16Å; I169-L220 HydrophobicContact CG1-CD1 4.5Å; I169-L220 HydrophobicContact CG2-CD1 4.22Å; A188-L220 HydrophobicContact CB-CD2 4.37Å; F215-L220 HydrophobicContact CD1-CB 4.29Å; F215-L220 HydrophobicContact CD1-CD2 4.49Å; F215-L220 HydrophobicContact CE1-CB 3.8Å; F215-L220 HydrophobicContact CE1-CD2 3.74Å; F215-L220 HydrophobicContact CE1-CG 4.32Å; F215-L220 HydrophobicContact CE2-CB 4.19Å; F215-L220 HydrophobicContact CZ-CB 3.72Å; F215-L220 HydrophobicContact CZ-CD2 4.23Å; F215-L220 HydrophobicContact CZ-CG 4.38Å; F215-L220 PolarHBondContact O-N 2.83Å; L220-T223 PolarHBondContact O-N 3.37Å; L220-L224 HydrophobicContact CD1-CD1 3.74Å; L220-L224 HydrophobicContact CD1-CG 3.98Å; L220-L224 HydrophobicContact CG-CD1 3.92Å; L220-L224 WeakPolarHBondContact O-CB 3.28Å; L220-L224 WeakPolarHBondContact O-CG 3.41Å; L220-L224 PolarHBondContact O-N 3.45Å; L220-L234 HydrophobicContact CD2-CD1 3.63Å; L220-L234 HydrophobicContact CD2-CD2 4.05Å; L220-L234 HydrophobicContact CG-CD1 4.41Å; L220-L234 HydrophobicContact CG-CD2 4.25Å
221G98.6Very high97.6Very high3 Ų342 Ų423%0.03123%0.227CC..Hα-helixtrans-58.5-56.2-179.700000112.8I216 T223 L224 A225 Y260I216-G221 WeakPolarHBondContact O-CA 3.34Å; I216-G221 PolarHBondContact O-N 2.96Å; G221-T223 VanDerWaalsContact C-N 3.32Å; G221-T223 PolarHBondContact O-N 3.09Å; G221-L224 PolarHBondContact O-N 2.71Å; G221-A225 VanDerWaalsContact O-CB 3.31Å; G221-A225 WeakPolarHBondContact O-CB 3.29Å; G221-A225 PolarHBondContact O-N 3.28Å; G221-Y260 VanDerWaalsContact CA-CG 3.46Å
222P98.6Very high97.6Very high28 Ų2841.4 Ų41.418%0.18223%0.225CC..Hα-helixtrans-59.4-38.3176-24.533.1000113.6I216 A217 A225 N226 Y260I216-P222 WeakPolarHBondContact O-CD 3.4Å; A217-P222 WeakPolarHBondContact O-CD 3.27Å; A217-P222 WeakPolarHBondContact O-CG 3.32Å; P222-A225 PolarHBondContact O-N 3.48Å; P222-N226 VanDerWaalsContact O-CB 3.31Å; P222-N226 WeakPolarHBondContact O-CB 3.36Å; P222-N226 PolarHBondContact O-N 3.29Å; P222-N226 PolarHBondContact O-ND2 2.84Å; P222-Y260 HydrophobicContact CG-CE2 3.97Å
223T98.6Very high97.6Very high24 Ų2447 Ų4715%0.14725%0.246CC..Hα-helixtrans-68-40.8-179.2-57.80000111.7A166 R167 V170 D219 L220 G221 G227A166-T223 HydrophobicContact CB-CG2 4.07Å; R167-T223 HydrophobicContact CG-CG2 4.24Å; V170-T223 HydrophobicContact CG2-CG2 3.65Å; D219-T223 WeakPolarHBondContact O-CB 3.33Å; D219-T223 PolarHBondContact O-N 2.77Å; D219-T223 PolarHBondContact O-OG1 2.95Å; L220-T223 PolarHBondContact O-N 3.37Å; G221-T223 VanDerWaalsContact C-N 3.32Å; G221-T223 PolarHBondContact O-N 3.09Å; T223-G227 PolarHBondContact O-N 3.11Å
224L97.9Very high97.6Very high10 Ų1044.3 Ų44.35%0.05224%0.236CC..Hα-helixtrans-66.9-45.2173-74.1170.3000111.8I169 V170 L173 V186 L220 G221 N226 G227 H230I169-L224 HydrophobicContact CG2-CD2 4.48Å; V170-L224 HydrophobicContact CG2-CD2 4.14Å; L173-L224 HydrophobicContact CD1-CD2 3.76Å; V186-L224 HydrophobicContact CG2-CD1 4.25Å; L220-L224 HydrophobicContact CD1-CD1 3.74Å; L220-L224 HydrophobicContact CD1-CG 3.98Å; L220-L224 HydrophobicContact CG-CD1 3.92Å; L220-L224 WeakPolarHBondContact O-CB 3.28Å; L220-L224 WeakPolarHBondContact O-CG 3.41Å; L220-L224 PolarHBondContact O-N 3.45Å; G221-L224 PolarHBondContact O-N 2.71Å; L224-N226 VanDerWaalsContact C-N 3.32Å; L224-N226 PolarHBondContact O-N 2.85Å; L224-G227 PolarHBondContact O-N 2.86Å; L224-H230 WeakPolarHBondContact O-CA 3.27Å; L224-H230 PolarHBondContact O-N 3.44Å
225A97.4Very high97.6Very high45 Ų4543.2 Ų43.237%0.37223%0.23SC..Hα-helixtrans-65.6-32.5-177.100000113.5G221 P222 H230 Y260G221-A225 VanDerWaalsContact O-CB 3.31Å; G221-A225 WeakPolarHBondContact O-CB 3.29Å; G221-A225 PolarHBondContact O-N 3.28Å; P222-A225 PolarHBondContact O-N 3.48Å; A225-H230 WeakPolarHBondContact O-CB 3.35Å; A225-Y260 HydrophobicContact CB-CE1 3.94Å
226N95.4Very high97.6Very high146 Ų14643.1 Ų43.178%0.78123%0.23SC*.THydrogen-bonded Turntrans-85.8-10.2178-67.7-16.9000113.4P222 L224P222-N226 VanDerWaalsContact O-CB 3.31Å; P222-N226 WeakPolarHBondContact O-CB 3.36Å; P222-N226 PolarHBondContact O-N 3.29Å; P222-N226 PolarHBondContact O-ND2 2.84Å; L224-N226 VanDerWaalsContact C-N 3.32Å; L224-N226 PolarHBondContact O-N 2.85Å
227G90.9Very high97.6Very high23 Ų2343.1 Ų43.124%0.23723%0.23CC..SBendtrans-89174.5179.100000113.5T223 L224 H229 H230T223-G227 PolarHBondContact O-N 3.11Å; L224-G227 PolarHBondContact O-N 2.86Å; G227-H229 PolarHBondContact O-N 3.37Å; G227-H230 PolarHBondContact O-N 2.93Å
228T94.4Very high97.6Very high111 Ų11142.5 Ų42.568%0.68123%0.225SC*.THydrogen-bonded Turntrans-65.6-16.5173.446.80000113.3
229H96.8Very high97.6Very high29 Ų2937.2 Ų37.213%0.13421%0.205CC..THydrogen-bonded Turntrans-98.221.2-177.6-54.9-70.2000113.8L173 D174 G227 N231 V232L173-H229 HydrophobicContact CB-CB 4.36Å; L173-H229 HydrophobicContact CD1-CB 3.76Å; L173-H229 PolarHBondContact O-CE1 3.03Å; D174-H229 PolarHBondContact N-NE2 2.92Å; D174-H229 IonicContact OD1-CD2 3.19Å; D174-H229 PolarHBondContact OD1-CD2 2.75Å; D174-H229 IonicContact OD1-CE1 3.94Å; D174-H229 IonicContact OD1-NE2 3.1Å; D174-H229 PolarHBondContact OD1-NE2 3.05Å; G227-H229 PolarHBondContact O-N 3.37Å; H229-N231 PolarHBondContact O-N 3.3Å; H229-V232 HydrophobicContact CB-CG2 3.91Å; H229-V232 VanDerWaalsContact O-CB 3.32Å; H229-V232 WeakPolarHBondContact O-CB 3.43Å; H229-V232 WeakPolarHBondContact O-CG2 3.08Å; H229-V232 PolarHBondContact O-N 2.91Å
230H95.8Very high97.5Very high107 Ų10737.8 Ų37.850%0.49521%0.208SC..THydrogen-bonded Turntrans-58.7-14.3-177.667.575.5000115.1L224 A225 G227L224-H230 WeakPolarHBondContact O-CA 3.27Å; L224-H230 PolarHBondContact O-N 3.44Å; A225-H230 WeakPolarHBondContact O-CB 3.35Å; G227-H230 PolarHBondContact O-N 2.93Å
231N97.1Very high97.3Very high115 Ų11538.4 Ų38.462%0.61521%0.21SC*.THydrogen-bonded Turntrans-83.3-16.8175.2-69-40.2000113.4H229 R233H229-N231 PolarHBondContact O-N 3.3Å; N231-R233 PolarHBondContact O-N 3.3Å
232V98.4Very high97.2Very high18 Ų1841.6 Ų41.611%0.10923%0.226CC..SBendtrans-66127.9176.5179.50000108.6L173 F183 V186 H229L173-V232 HydrophobicContact CD1-CG1 4.46Å; L173-V232 HydrophobicContact CD1-CG2 4.27Å; L173-V232 HydrophobicContact CD2-CG2 4.49Å; F183-V232 HydrophobicContact CB-CG1 4.31Å; F183-V232 HydrophobicContact CB-CG2 4.39Å; V186-V232 HydrophobicContact CG1-CG1 4.02Å; V186-V232 HydrophobicContact CG2-CG1 4.27Å; H229-V232 HydrophobicContact CB-CG2 3.91Å; H229-V232 VanDerWaalsContact O-CB 3.32Å; H229-V232 WeakPolarHBondContact O-CB 3.43Å; H229-V232 WeakPolarHBondContact O-CG2 3.08Å; H229-V232 PolarHBondContact O-N 2.91Å
233R98.7Very high97.2Very high117 Ų11742.3 Ų42.344%0.44223%0.228SC..EExtended strand (participates in β ladder)trans-77.8144.8-179.6-54-55.6-176.5-176.9-3110.6W184 A185 V186 N231 H262W184-R233 WeakPolarHBondContact O-CG 3.37Å; W184-R233 PolarHBondContact O-N 3.19Å; A185-R233 CarbonylContact C-O 3.56Å; A185-R233 WeakPolarHBondContact CA-O 3.08Å; A185-R233 HydrophobicContact CB-CB 3.94Å; V186-R233 PolarHBondContact N-O 3.11Å; N231-R233 PolarHBondContact O-N 3.3Å; R233-H262 HydrophobicContact CB-CB 3.83Å; R233-H262 HydrophobicContact CG-CB 4.37Å
234L98.9Very high97.2Very high5 Ų541.6 Ų41.63%0.02622%0.223CC..EExtended strand (participates in β ladder)trans-105.2123.817317861.9000110.2V186 A188 I216 L220 H262V186-L234 HydrophobicContact CG2-CD1 4.02Å; V186-L234 WeakPolarHBondContact O-CA 3.48Å; A188-L234 HydrophobicContact CB-CD1 4.28Å; I216-L234 HydrophobicContact CD1-CD2 4.37Å; I216-L234 HydrophobicContact CG1-CD2 4.12Å; I216-L234 HydrophobicContact CG2-CD2 3.86Å; L220-L234 HydrophobicContact CD2-CD1 3.63Å; L220-L234 HydrophobicContact CD2-CD2 4.05Å; L220-L234 HydrophobicContact CG-CD1 4.41Å; L220-L234 HydrophobicContact CG-CD2 4.25Å; L234-H262 PolarHBondContact O-N 3.43Å
235L98.9Very high97.2Very high0 Ų042.4 Ų42.40%023%0.229CC..EExtended strand (participates in β ladder)trans-102.6130.7171.9-49.7-173.1000109.9L131 A185 V186 T187 A188 G263 A265 M291 F293L131-L235 HydrophobicContact CD1-CD1 4.06Å; L131-L235 HydrophobicContact CD2-CD1 4.44Å; A185-L235 HydrophobicContact CB-CD1 4.47Å; A185-L235 HydrophobicContact CB-CG 4.31Å; V186-L235 PolarHBondContact O-N 3.39Å; T187-L235 CarbonylContact C-O 3.5Å; T187-L235 VanDerWaalsContact CA-O 3.28Å; T187-L235 WeakPolarHBondContact CA-O 3.49Å; T187-L235 HydrophobicContact CG2-CB 4.16Å; A188-L235 PolarHBondContact N-O 3.46Å; L235-G263 WeakPolarHBondContact CA-O 3.31Å; L235-A265 HydrophobicContact CB-CB 4Å; L235-A265 HydrophobicContact CD1-CB 4.2Å; L235-M291 HydrophobicContact CD2-CE 3.76Å; L235-M291 HydrophobicContact CD2-SD 4.37Å; L235-F293 HydrophobicContact CD1-CB 4.48Å; L235-F293 HydrophobicContact CD1-CD1 4.18Å
236M98.8Very high97.2Very high0 Ų045.6 Ų45.60%024%0.236CC..EExtended strand (participates in β ladder)trans-90.2174.7174.369.2166.4-74.200111.3I216 D238 W247 V251 L252 V261 G263 I264 A265I216-M236 HydrophobicContact CD1-CB 4.22Å; M236-D238 PolarHBondContact O-N 3.46Å; M236-D238 VanDerWaalsContact O-N 3.08Å; M236-W247 HydrophobicContact CE-CE3 3.74Å; M236-W247 HydrophobicContact CE-CZ3 4.4Å; M236-V251 HydrophobicContact CE-CB 3.49Å; M236-V251 VanDerWaalsContact CE-CB 3.49Å; M236-V251 HydrophobicContact CE-CG1 3.99Å; M236-V251 HydrophobicContact CE-CG2 3.42Å; M236-V251 VanDerWaalsContact CE-CG2 3.42Å; M236-V251 HydrophobicContact SD-CB 3.73Å; M236-V251 HydrophobicContact SD-CG1 3.71Å; M236-V251 HydrophobicContact SD-CG2 4.28Å; M236-L252 HydrophobicContact SD-CD1 4.28Å; M236-L252 HydrophobicContact SD-CD2 3.87Å; M236-L252 HydrophobicContact SD-CG 3.86Å; M236-V261 HydrophobicContact CB-CG1 4Å; M236-V261 HydrophobicContact CB-CG2 4.38Å; M236-V261 HydrophobicContact CG-CG1 3.67Å; M236-V261 HydrophobicContact SD-CG1 4.03Å; M236-G263 PolarHBondContact N-O 2.99Å; M236-I264 HydrophobicContact CG-CB 4.29Å; M236-I264 HydrophobicContact CG-CG1 3.73Å; M236-I264 HydrophobicContact SD-CG1 3.99Å; M236-A265 PolarHBondContact O-N 2.86Å
237L98.8Very high97.4Very high0 Ų039.1 Ų39.10%020%0.201CC..EExtended strand (participates in β ladder)trans68.4-85.5-177.9-173.565.1000114.1P192 D239 L243 L244 W247 I264 A265 V266P192-L237 WeakPolarHBondContact CD-O 3.45Å; P192-L237 VanDerWaalsContact CG-O 3.25Å; P192-L237 WeakPolarHBondContact CG-O 3.36Å; L237-D239 VanDerWaalsContact C-N 3.31Å; L237-D239 HydrophobicContact CD1-CB 3.72Å; L237-D239 HydrophobicContact CG-CB 3.99Å; L237-D239 PolarHBondContact O-N 2.91Å; L237-L243 HydrophobicContact CD1-CB 4.05Å; L237-L243 HydrophobicContact CD1-CD1 3.95Å; L237-L244 HydrophobicContact CD2-CD1 4.08Å; L237-L244 HydrophobicContact CD2-CD2 3.8Å; L237-L244 HydrophobicContact CD2-CG 3.72Å; L237-W247 VanDerWaalsContact CA-CZ3 3.43Å; L237-W247 HydrophobicContact CB-CE3 3.87Å; L237-W247 HydrophobicContact CB-CZ3 4.18Å; L237-W247 HydrophobicContact CD1-CB 4.07Å; L237-W247 HydrophobicContact CD1-CD2 3.59Å; L237-W247 HydrophobicContact CD1-CE3 3.47Å; L237-W247 VanDerWaalsContact CD1-CE3 3.47Å; L237-W247 HydrophobicContact CD1-CG 3.83Å; L237-W247 HydrophobicContact CD1-CZ3 4.03Å; L237-W247 HydrophobicContact CG-CE3 4.28Å; L237-I264 HydrophobicContact CB-CG2 3.89Å; L237-I264 HydrophobicContact CD2-CG2 3.83Å; L237-A265 WeakPolarHBondContact CB-O 3.29Å; L237-A265 WeakPolarHBondContact CG-O 3.4Å; L237-V266 HydrophobicContact CD2-CG1 4.05Å
238D98.6Very high97.8Very high0 Ų038 Ų380%019%0.19CC..EExtended strand (participates in β ladder)trans53.348.1-174.1-154.637.6000112.3S133 T187 E189 E191 M236 A265 H267 S295S133-D238 WeakPolarHBondContact CB-OD2 3.47Å; S133-D238 PolarHBondContact OG-OD2 3.27Å; T187-D238 VanDerWaalsContact CB-OD2 3.22Å; T187-D238 WeakPolarHBondContact CB-OD2 3.5Å; T187-D238 HydrophobicContact CG2-CB 3.99Å; T187-D238 VanDerWaalsContact CG2-CG 3.47Å; T187-D238 VanDerWaalsContact CG2-OD2 3.25Å; T187-D238 WeakPolarHBondContact CG2-OD2 3.38Å; T187-D238 PolarHBondContact OG1-OD2 3.24Å; E189-D238 WeakPolarHBondContact O-CB 3.37Å; E191-D238 WeakPolarHBondContact CA-O 3.39Å; E191-D238 PolarHBondContact N-O 3.14Å; M236-D238 PolarHBondContact O-N 3.46Å; M236-D238 VanDerWaalsContact O-N 3.08Å; D238-A265 WeakPolarHBondContact CA-O 3.22Å; D238-A265 HydrophobicContact CB-CB 3.85Å; D238-A265 PolarHBondContact N-O 3.45Å; D238-A265 WeakPolarHBondContact OD1-CB 3.42Å; D238-H267 PolarHBondContact O-CE1 3.08Å; D238-H267 VanDerWaalsContact O-CE1 3.27Å; D238-H267 PolarHBondContact O-NE2 3.33Å; D238-H267 IonicContact OD1-CD2 2.66Å; D238-H267 IonicContact OD1-NE2 3.78Å; D238-H267 PolarHBondContact OD1-NE2 3.41Å; D238-H267 VanDerWaalsContact OD1-NE2 3.1Å; D238-S295 WeakPolarHBondContact OD1-CB 3.44Å; D238-S295 PolarHBondContact OD1-OG 3.47Å
239D98.6Very high98Very high1 Ų137.2 Ų37.21%0.00518%0.177CC..EExtended strand (participates in β ladder)trans-154.2177.1-172-151.1-33.9000109.8E191 P192 S193 L237 R241 L243 V266 H267E191-D239 VanDerWaalsContact C-OD2 3.28Å; E191-D239 WeakPolarHBondContact CA-OD2 3.45Å; P192-D239 HydrophobicContact CG-CB 4.47Å; S193-D239 WeakPolarHBondContact CB-OD2 3.29Å; S193-D239 PolarHBondContact N-OD2 3.28Å; S193-D239 PolarHBondContact OG-OD1 2.8Å; S193-D239 PolarHBondContact OG-OD2 3.36Å; L237-D239 VanDerWaalsContact C-N 3.31Å; L237-D239 HydrophobicContact CD1-CB 3.72Å; L237-D239 HydrophobicContact CG-CB 3.99Å; L237-D239 PolarHBondContact O-N 2.91Å; D239-R241 PolarHBondContact O-N 2.91Å; D239-L243 HydrophobicContact CB-CD1 3.89Å; D239-V266 CarbonylContact O-C 3.57Å; D239-V266 WeakPolarHBondContact O-CA 3.47Å; D239-H267 PolarHBondContact O-N 2.54Å
240Q97.5Very high98.1Very high11 Ų1136.8 Ų36.85%0.05118%0.176CC..EExtended strand (participates in β ladder)trans-55.9134.6-175.7-50.5-45.4-50.600112.6E191 L242 L243 L270E191-Q240 PolarHBondContact OE1-NE2 3.32Å; Q240-L242 HydrophobicContact CB-CD2 3.16Å; Q240-L242 HydrophobicContact CG-CD2 4.1Å; Q240-L242 PolarHBondContact O-N 2.9Å; Q240-L243 PolarHBondContact O-N 3.28Å; Q240-L243 VanDerWaalsContact O-N 3.11Å; Q240-L270 HydrophobicContact CB-CB 4.4Å; Q240-L270 HydrophobicContact CB-CD1 4.34Å; Q240-L270 HydrophobicContact CG-CB 4.4Å; Q240-L270 HydrophobicContact CG-CD1 3.89Å; Q240-L270 HydrophobicContact CG-CG 4.01Å
241R95.3Very high98.2Very high13 Ų1331.7 Ų31.75%0.04915%0.153CC..G310 helixtrans-63.6-12.2-177.769.7174.7177.373.16.7115.5D239 L243 L244 V266 H267 D271 A274 P275 T279 L280D239-R241 PolarHBondContact O-N 2.91Å; R241-L243 PolarHBondContact O-N 3.02Å; R241-L244 WeakPolarHBondContact O-CB 3.18Å; R241-L244 PolarHBondContact O-N 3.43Å; R241-L244 VanDerWaalsContact O-N 3.09Å; R241-V266 HydrophobicContact CB-CB 4.35Å; R241-V266 HydrophobicContact CB-CG1 4.39Å; R241-H267 PolarHBondContact N-O 3.29Å; R241-D271 WeakPolarHBondContact CD-OD1 3.41Å; R241-D271 WeakPolarHBondContact CG-OD1 3.45Å; R241-D271 IonicContact CZ-OD1 3.66Å; R241-D271 IonicContact CZ-OD2 2.65Å; R241-D271 IonicContact NE-OD1 2.82Å; R241-D271 PolarHBondContact NE-OD1 2.97Å; R241-D271 IonicContact NE-OD2 2.94Å; R241-D271 PolarHBondContact NE-OD2 3.47Å; R241-D271 PolarHBondContact NH2-O 3.34Å; R241-D271 IonicContact NH2-OD1 3.84Å; R241-D271 IonicContact NH2-OD2 3.87Å; R241-D271 PolarHBondContact NH2-OD2 2.85Å; R241-A274 PolarHBondContact NH1-O 3.37Å; R241-A274 PolarHBondContact NH2-O 3.1Å; R241-P275 PolarHBondContact NH1-O 3.15Å; R241-T279 PolarHBondContact NH1-OG1 3.47Å; R241-T279 WeakPolarHBondContact O-CB 3.26Å; R241-T279 WeakPolarHBondContact O-CG2 3.49Å; R241-L280 HydrophobicContact CB-CD2 4.29Å
242L96.4Very high98.3Very high71 Ų7127 Ų2737%0.37213%0.127SC..G310 helixtrans-63.9-20.7173.485.9169.2000113.2Q240 L244 L270 L273Q240-L242 HydrophobicContact CB-CD2 3.16Å; Q240-L242 HydrophobicContact CG-CD2 4.1Å; Q240-L242 PolarHBondContact O-N 2.9Å; L242-L244 PolarHBondContact O-N 2.64Å; L242-L270 HydrophobicContact CD1-CD1 4.11Å; L242-L270 HydrophobicContact CD2-CB 4.29Å; L242-L270 HydrophobicContact CD2-CD1 3.9Å; L242-L273 HydrophobicContact CD1-CD1 4.22Å
243L97.9Very high98.3Very high43 Ų4330.9 Ų30.923%0.22515%0.151CC..G310 helixtrans-74.1-12.1176.1-61.4175.9000112.1L237 D239 Q240 R241 H246 W247L237-L243 HydrophobicContact CD1-CB 4.05Å; L237-L243 HydrophobicContact CD1-CD1 3.95Å; D239-L243 HydrophobicContact CB-CD1 3.89Å; Q240-L243 PolarHBondContact O-N 3.28Å; Q240-L243 VanDerWaalsContact O-N 3.11Å; R241-L243 PolarHBondContact O-N 3.02Å; L243-H246 PolarHBondContact O-N 3.21Å; L243-W247 HydrophobicContact CB-CB 4.49Å; L243-W247 HydrophobicContact CB-CG 4.41Å; L243-W247 PolarHBondContact O-N 2.89Å
244L98.3Very high98.3Very high8 Ų827.2 Ų27.24%0.04214%0.14CC..THydrogen-bonded Turntrans-88.3148.5173.6-67.3178.8000112L237 R241 L242 A248 I264 V266 L280 T283 L292L237-L244 HydrophobicContact CD2-CD1 4.08Å; L237-L244 HydrophobicContact CD2-CD2 3.8Å; L237-L244 HydrophobicContact CD2-CG 3.72Å; R241-L244 WeakPolarHBondContact O-CB 3.18Å; R241-L244 PolarHBondContact O-N 3.43Å; R241-L244 VanDerWaalsContact O-N 3.09Å; L242-L244 PolarHBondContact O-N 2.64Å; L244-A248 HydrophobicContact CD2-CB 3.8Å; L244-I264 HydrophobicContact CD1-CG2 4.27Å; L244-I264 HydrophobicContact CD2-CG2 4.16Å; L244-V266 HydrophobicContact CD1-CG1 3.6Å; L244-L280 HydrophobicContact CD1-CD2 4.32Å; L244-T283 WeakPolarHBondContact CB-OG1 3.32Å; L244-T283 HydrophobicContact CD1-CG2 4.36Å; L244-T283 HydrophobicContact CD2-CG2 4.1Å; L244-L292 HydrophobicContact CD1-CD2 4.28Å
245P98.1Very high98.3Very high28 Ų2831.3 Ų31.318%0.18217%0.167CC..THydrogen-bonded Turncis-884.22.335.1-36.5000113.9W247 A248 K249 E282 T283 L286P245-W247 PolarHBondContact O-N 3.11Å; P245-A248 PolarHBondContact O-N 3.23Å; P245-K249 WeakPolarHBondContact O-CG 3.49Å; P245-K249 PolarHBondContact O-N 3.02Å; P245-E282 HydrophobicContact CG-CB 4.49Å; P245-T283 WeakPolarHBondContact CA-OG1 3.37Å; P245-T283 WeakPolarHBondContact CB-OG1 3.35Å; P245-L286 HydrophobicContact CB-CD1 4.03Å
246H98.7Very high98.3Very high112 Ų11236 Ų3652%0.51919%0.189SC..Hα-helixtrans-61.1-48.8-172175.761.6000112.5L243 A248 K249 V250L243-H246 PolarHBondContact O-N 3.21Å; H246-A248 VanDerWaalsContact C-N 3.33Å; H246-A248 PolarHBondContact O-N 2.94Å; H246-K249 WeakPolarHBondContact O-CB 3.44Å; H246-K249 PolarHBondContact O-N 3.27Å; H246-K249 VanDerWaalsContact O-N 3.11Å; H246-V250 PolarHBondContact O-N 3.14Å
247W98.8Very high98.3Very high9 Ų936 Ų363%0.03419%0.189CC..Hα-helixtrans-57.1-45.7178.4-115.571.7000112.6P192 P209 Q212 M236 L237 L243 P245 K249 V250 V251P192-W247 HydrophobicContact CB-CH2 3.86Å; P192-W247 HydrophobicContact CB-CZ2 4.12Å; P192-W247 HydrophobicContact CG-CH2 3.38Å; P192-W247 HydrophobicContact CG-CZ2 3.82Å; P192-W247 HydrophobicContact CG-CZ3 4.1Å; P209-W247 HydrophobicContact CB-CD2 3.82Å; P209-W247 HydrophobicContact CB-CG 3.79Å; P209-W247 HydrophobicContact CB-CZ2 4.29Å; P209-W247 HydrophobicContact CG-CG 4.42Å; Q212-W247 HydrophobicContact CB-CH2 3.6Å; Q212-W247 HydrophobicContact CB-CZ2 4.35Å; Q212-W247 HydrophobicContact CB-CZ3 4.06Å; Q212-W247 HydrophobicContact CG-CH2 4Å; Q212-W247 HydrophobicContact CG-CZ3 4.15Å; M236-W247 HydrophobicContact CE-CE3 3.74Å; M236-W247 HydrophobicContact CE-CZ3 4.4Å; L237-W247 VanDerWaalsContact CA-CZ3 3.43Å; L237-W247 HydrophobicContact CB-CE3 3.87Å; L237-W247 HydrophobicContact CB-CZ3 4.18Å; L237-W247 HydrophobicContact CD1-CB 4.07Å; L237-W247 HydrophobicContact CD1-CD2 3.59Å; L237-W247 HydrophobicContact CD1-CE3 3.47Å; L237-W247 VanDerWaalsContact CD1-CE3 3.47Å; L237-W247 HydrophobicContact CD1-CG 3.83Å; L237-W247 HydrophobicContact CD1-CZ3 4.03Å; L237-W247 HydrophobicContact CG-CE3 4.28Å; L243-W247 HydrophobicContact CB-CB 4.49Å; L243-W247 HydrophobicContact CB-CG 4.41Å; L243-W247 PolarHBondContact O-N 2.89Å; P245-W247 PolarHBondContact O-N 3.11Å; W247-K249 VanDerWaalsContact C-N 3.34Å; W247-K249 PolarHBondContact O-N 3.14Å; W247-V250 PolarHBondContact O-N 3.27Å; W247-V251 PolarHBondContact O-N 3.21Å; W247-V251 VanDerWaalsContact O-N 3.15Å
248A98.8Very high98.3Very high0 Ų037.5 Ų37.50%020%0.201CC..Hα-helixtrans-60.6-42.1175.800000111.9L244 P245 H246 L252 I264 T283 F287L244-A248 HydrophobicContact CD2-CB 3.8Å; P245-A248 PolarHBondContact O-N 3.23Å; H246-A248 VanDerWaalsContact C-N 3.33Å; H246-A248 PolarHBondContact O-N 2.94Å; A248-L252 HydrophobicContact CB-CD1 4.24Å; A248-L252 WeakPolarHBondContact O-CB 3.45Å; A248-L252 WeakPolarHBondContact O-CG 3.27Å; A248-L252 PolarHBondContact O-N 3.28Å; A248-I264 HydrophobicContact CB-CD1 3.82Å; A248-T283 HydrophobicContact CB-CG2 3.77Å; A248-F287 HydrophobicContact CB-CD2 3.98Å; A248-F287 HydrophobicContact CB-CE2 3.9Å
249K98.8Very high98.3Very high94 Ų9442.9 Ų42.941%0.40923%0.225SC..Hα-helixtrans-60-48.4176-71.6175.2-179.9-177.60111.9P245 H246 W247 V251 T253 L286 F287P245-K249 WeakPolarHBondContact O-CG 3.49Å; P245-K249 PolarHBondContact O-N 3.02Å; H246-K249 WeakPolarHBondContact O-CB 3.44Å; H246-K249 PolarHBondContact O-N 3.27Å; H246-K249 VanDerWaalsContact O-N 3.11Å; W247-K249 VanDerWaalsContact C-N 3.34Å; W247-K249 PolarHBondContact O-N 3.14Å; K249-V251 VanDerWaalsContact C-N 3.35Å; K249-V251 PolarHBondContact O-N 3.11Å; K249-T253 VanDerWaalsContact O-CB 3.27Å; K249-T253 WeakPolarHBondContact O-CB 3.38Å; K249-T253 WeakPolarHBondContact O-CG2 3.25Å; K249-T253 PolarHBondContact O-N 3.48Å; K249-T253 PolarHBondContact O-OG1 2.7Å; K249-L286 HydrophobicContact CD-CD1 4.35Å; K249-L286 HydrophobicContact CG-CD1 4.18Å; K249-F287 HydrophobicContact CG-CE2 4.18Å; K249-F287 HydrophobicContact CG-CZ 4.34Å
250V98.9Very high98.3Very high21 Ų2146 Ų4613%0.12724%0.237CC..Hα-helixtrans-62.7-42.4-176.7173.80000111.7P209 E210 R213 H246 W247P209-V250 HydrophobicContact CB-CB 3.79Å; P209-V250 HydrophobicContact CB-CG1 3.75Å; P209-V250 HydrophobicContact CB-CG2 4.16Å; P209-V250 HydrophobicContact CG-CB 4.38Å; P209-V250 HydrophobicContact CG-CG1 4.31Å; P209-V250 HydrophobicContact CG-CG2 4.22Å; E210-V250 HydrophobicContact CB-CG1 4.46Å; E210-V250 HydrophobicContact CG-CG1 3.91Å; R213-V250 VanDerWaalsContact CD-O 3.31Å; R213-V250 WeakPolarHBondContact CD-O 3.32Å; H246-V250 PolarHBondContact O-N 3.14Å; W247-V250 PolarHBondContact O-N 3.27Å
251V98.9Very high98.4Very high0 Ų046.1 Ų46.10%024%0.238CC..Hα-helixtrans-80.9-47.2-177.4-179.20000112.3R213 I216 M236 W247 K249 D254 A257 V261R213-V251 HydrophobicContact CB-CB 4.41Å; R213-V251 HydrophobicContact CB-CG1 4.49Å; R213-V251 HydrophobicContact CB-CG2 4.04Å; I216-V251 HydrophobicContact CD1-CG1 4.36Å; M236-V251 HydrophobicContact CE-CB 3.49Å; M236-V251 VanDerWaalsContact CE-CB 3.49Å; M236-V251 HydrophobicContact CE-CG1 3.99Å; M236-V251 HydrophobicContact CE-CG2 3.42Å; M236-V251 VanDerWaalsContact CE-CG2 3.42Å; M236-V251 HydrophobicContact SD-CB 3.73Å; M236-V251 HydrophobicContact SD-CG1 3.71Å; M236-V251 HydrophobicContact SD-CG2 4.28Å; W247-V251 PolarHBondContact O-N 3.21Å; W247-V251 VanDerWaalsContact O-N 3.15Å; K249-V251 VanDerWaalsContact C-N 3.35Å; K249-V251 PolarHBondContact O-N 3.11Å; V251-D254 PolarHBondContact O-N 2.88Å; V251-A257 HydrophobicContact CG1-CB 4.08Å; V251-V261 HydrophobicContact CG1-CG2 4.2Å
252L98.8Very high98.5Very high16 Ų1648.7 Ų48.78%0.08425%0.251CS..Hα-helixtrans-85.7-13.5-168.5-59.3177.2000114.3M236 A248 D254 A258 V261 I264 F287 T290M236-L252 HydrophobicContact SD-CD1 4.28Å; M236-L252 HydrophobicContact SD-CD2 3.87Å; M236-L252 HydrophobicContact SD-CG 3.86Å; A248-L252 HydrophobicContact CB-CD1 4.24Å; A248-L252 WeakPolarHBondContact O-CB 3.45Å; A248-L252 WeakPolarHBondContact O-CG 3.27Å; A248-L252 PolarHBondContact O-N 3.28Å; L252-D254 VanDerWaalsContact C-N 3.27Å; L252-A258 HydrophobicContact CD2-CB 4.37Å; L252-V261 HydrophobicContact CD2-CB 3.91Å; L252-V261 HydrophobicContact CD2-CG1 3.87Å; L252-V261 HydrophobicContact CD2-CG2 4.33Å; L252-I264 HydrophobicContact CD1-CD1 3.93Å; L252-I264 HydrophobicContact CD1-CG1 4.38Å; L252-F287 HydrophobicContact CB-CD1 3.75Å; L252-F287 HydrophobicContact CB-CE1 3.56Å; L252-F287 HydrophobicContact CB-CE2 4.43Å; L252-F287 HydrophobicContact CB-CG 4.28Å; L252-F287 HydrophobicContact CB-CZ 3.94Å; L252-F287 HydrophobicContact CD1-CB 3.94Å; L252-F287 HydrophobicContact CD1-CD1 3.91Å; L252-F287 HydrophobicContact CD1-CD2 3.88Å; L252-F287 HydrophobicContact CD1-CE1 4.42Å; L252-F287 HydrophobicContact CD1-CE2 4.38Å; L252-F287 HydrophobicContact CD1-CG 3.62Å; L252-T290 HydrophobicContact CD1-CG2 3.94Å; L252-T290 HydrophobicContact CD2-CG2 4.5Å
253T98.8Very high98.6Very high99 Ų9945.3 Ų45.361%0.60723%0.233SC*.THydrogen-bonded Turntrans-77.6-15.7170.658.20000112.5K249 P255 F287K249-T253 VanDerWaalsContact O-CB 3.27Å; K249-T253 WeakPolarHBondContact O-CB 3.38Å; K249-T253 WeakPolarHBondContact O-CG2 3.25Å; K249-T253 PolarHBondContact O-N 3.48Å; K249-T253 PolarHBondContact O-OG1 2.7Å; T253-P255 WeakPolarHBondContact O-CD 3.36Å; T253-F287 HydrophobicContact CG2-CE1 4.46Å; T253-F287 HydrophobicContact CG2-CZ 4.17Å
254D98.8Very high98.7Very high40 Ų4043.3 Ų43.321%0.21422%0.223CC..SBendtrans-88.5111.5170.4-175.1-22000109.8R213 V251 L252 E256 A257 A258R213-D254 WeakPolarHBondContact CD-OD2 3.48Å; R213-D254 HydrophobicContact CG-CB 3.95Å; R213-D254 IonicContact NE-OD2 3.79Å; V251-D254 PolarHBondContact O-N 2.88Å; L252-D254 VanDerWaalsContact C-N 3.27Å; D254-E256 PolarHBondContact O-N 3.16Å; D254-E256 WeakPolarHBondContact OD1-CB 3.26Å; D254-E256 PolarHBondContact OD1-N 3.42Å; D254-A257 HydrophobicContact CB-CB 4.42Å; D254-A257 PolarHBondContact O-N 3.34Å; D254-A258 VanDerWaalsContact O-CB 3.31Å; D254-A258 WeakPolarHBondContact O-CB 3.32Å; D254-A258 PolarHBondContact O-N 3.36Å
255P98.6Very high98.7Very high91 Ų9142.9 Ų42.959%0.59122%0.221SC*.Hα-helixtrans-63.8-24.3-177.227.2-34.9000113.3T253 K259T253-P255 WeakPolarHBondContact O-CD 3.36Å; P255-K259 PolarHBondContact O-N 3.45Å
256E98.6Very high98.7Very high100 Ų10041.8 Ų41.847%0.46721%0.213SC..Hα-helixtrans-75.1-28.5-180-67.1-60.910400112.3A217 D254 K259 Y260A217-E256 HydrophobicContact CB-CB 4.12Å; D254-E256 PolarHBondContact O-N 3.16Å; D254-E256 WeakPolarHBondContact OD1-CB 3.26Å; D254-E256 PolarHBondContact OD1-N 3.42Å; E256-K259 WeakPolarHBondContact O-CE 3.48Å; E256-K259 IonicContact OE1-NZ 2.71Å; E256-K259 PolarHBondContact OE1-NZ 3.17Å; E256-K259 IonicContact OE2-NZ 2.8Å; E256-K259 PolarHBondContact OE2-NZ 2.77Å; E256-Y260 VanDerWaalsContact O-CD2 3.3Å; E256-Y260 WeakPolarHBondContact O-CD2 3.35Å; E256-Y260 WeakPolarHBondContact O-CE2 3.33Å
257A98.7Very high98.6Very high0 Ų036.6 Ų36.60%019%0.189CC..Hα-helixtrans-83.7-47.7168.700000111.2R213 I216 A217 V251 D254 K259 Y260 V261R213-A257 HydrophobicContact CG-CB 3.79Å; I216-A257 HydrophobicContact CG2-CB 4.33Å; A217-A257 HydrophobicContact CB-CB 4.07Å; V251-A257 HydrophobicContact CG1-CB 4.08Å; D254-A257 HydrophobicContact CB-CB 4.42Å; D254-A257 PolarHBondContact O-N 3.34Å; A257-K259 VanDerWaalsContact C-N 3.26Å; A257-K259 PolarHBondContact O-N 3Å; A257-K259 VanDerWaalsContact O-N 3.15Å; A257-Y260 PolarHBondContact O-N 3.31Å; A257-V261 PolarHBondContact O-N 2.83Å
258A98.7Very high98.1Very high30 Ų3037.8 Ų37.825%0.24819%0.194CC..Hα-helixtrans-57.2-35.2-171.600000113.4L252 D254 Y260 V261L252-A258 HydrophobicContact CD2-CB 4.37Å; D254-A258 VanDerWaalsContact O-CB 3.31Å; D254-A258 WeakPolarHBondContact O-CB 3.32Å; D254-A258 PolarHBondContact O-N 3.36Å; A258-Y260 PolarHBondContact O-N 2.96Å; A258-Y260 VanDerWaalsContact O-N 3.16Å; A258-V261 PolarHBondContact O-N 3.41Å; A258-V261 VanDerWaalsContact O-N 3.16Å
259K98.5Very high97.4Very high114 Ų11439.4 Ų39.450%0.49620%0.2SC..THydrogen-bonded Turntrans-62.1-20.9178.369.9-172.3175.2-163.90114.4P255 E256 A257P255-K259 PolarHBondContact O-N 3.45Å; E256-K259 WeakPolarHBondContact O-CE 3.48Å; E256-K259 IonicContact OE1-NZ 2.71Å; E256-K259 PolarHBondContact OE1-NZ 3.17Å; E256-K259 IonicContact OE2-NZ 2.8Å; E256-K259 PolarHBondContact OE2-NZ 2.77Å; A257-K259 VanDerWaalsContact C-N 3.26Å; A257-K259 PolarHBondContact O-N 3Å; A257-K259 VanDerWaalsContact O-N 3.15Å
260Y98.8Very high96.5Very high65 Ų6537.8 Ų37.826%0.25520%0.196SC..THydrogen-bonded Turntrans-97.8-18.3177.9-61.7-62.1000113.2G221 P222 A225 E256 A257 A258G221-Y260 VanDerWaalsContact CA-CG 3.46Å; P222-Y260 HydrophobicContact CG-CE2 3.97Å; A225-Y260 HydrophobicContact CB-CE1 3.94Å; E256-Y260 VanDerWaalsContact O-CD2 3.3Å; E256-Y260 WeakPolarHBondContact O-CD2 3.35Å; E256-Y260 WeakPolarHBondContact O-CE2 3.33Å; A257-Y260 PolarHBondContact O-N 3.31Å; A258-Y260 PolarHBondContact O-N 2.96Å; A258-Y260 VanDerWaalsContact O-N 3.16Å
261V98.8Very high95.8Very high14 Ų1438.7 Ų38.79%0.08520%0.2CC..EExtended strand (participates in β ladder)trans-86.4120.2-176.9-179.90000110.2I216 M236 V251 L252 A257 A258 G263 T290I216-V261 HydrophobicContact CD1-CG2 4.1Å; I216-V261 HydrophobicContact CG2-CG2 4.02Å; M236-V261 HydrophobicContact CB-CG1 4Å; M236-V261 HydrophobicContact CB-CG2 4.38Å; M236-V261 HydrophobicContact CG-CG1 3.67Å; M236-V261 HydrophobicContact SD-CG1 4.03Å; V251-V261 HydrophobicContact CG1-CG2 4.2Å; L252-V261 HydrophobicContact CD2-CB 3.91Å; L252-V261 HydrophobicContact CD2-CG1 3.87Å; L252-V261 HydrophobicContact CD2-CG2 4.33Å; A257-V261 PolarHBondContact O-N 2.83Å; A258-V261 PolarHBondContact O-N 3.41Å; A258-V261 VanDerWaalsContact O-N 3.16Å; V261-G263 VanDerWaalsContact CG1-O 3.28Å; V261-G263 WeakPolarHBondContact CG1-O 3.31Å; V261-T290 HydrophobicContact CG1-CG2 4.43Å
262H98.6Very high95Very high68 Ų6844.8 Ų44.832%0.31523%0.226SC..EExtended strand (participates in β ladder)trans-87-34.5176.4-179.258.2000112.7R233 L234R233-H262 HydrophobicContact CB-CB 3.83Å; R233-H262 HydrophobicContact CG-CB 4.37Å; L234-H262 PolarHBondContact O-N 3.43Å
263G98.5Very high93.9Very high0 Ų049 Ų490%025%0.248CC..EExtended strand (participates in β ladder)trans-162177-174.600000113.1L235 M236 V261 M291L235-G263 WeakPolarHBondContact CA-O 3.31Å; M236-G263 PolarHBondContact N-O 2.99Å; V261-G263 VanDerWaalsContact CG1-O 3.28Å; V261-G263 WeakPolarHBondContact CG1-O 3.31Å; G263-M291 CarbonylContact C-O 3.49Å; G263-M291 WeakPolarHBondContact CA-O 3.15Å
264I98.9Very high93.1Very high0 Ų045.3 Ų45.30%023%0.228CC..EExtended strand (participates in β ladder)trans-118.9119.5178.4-59.2160.9000107.4M236 L237 L244 A248 L252 V266 T283 T290 M291 L292 F293M236-I264 HydrophobicContact CG-CB 4.29Å; M236-I264 HydrophobicContact CG-CG1 3.73Å; M236-I264 HydrophobicContact SD-CG1 3.99Å; L237-I264 HydrophobicContact CB-CG2 3.89Å; L237-I264 HydrophobicContact CD2-CG2 3.83Å; L244-I264 HydrophobicContact CD1-CG2 4.27Å; L244-I264 HydrophobicContact CD2-CG2 4.16Å; A248-I264 HydrophobicContact CB-CD1 3.82Å; L252-I264 HydrophobicContact CD1-CD1 3.93Å; L252-I264 HydrophobicContact CD1-CG1 4.38Å; I264-V266 HydrophobicContact CG2-CG1 4.24Å; I264-T283 HydrophobicContact CD1-CG2 3.49Å; I264-T283 VanDerWaalsContact CD1-CG2 3.49Å; I264-T290 HydrophobicContact CD1-CG2 4.14Å; I264-T290 HydrophobicContact CG1-CG2 3.92Å; I264-M291 PolarHBondContact N-O 2.79Å; I264-L292 HydrophobicContact CB-CD2 3.99Å; I264-L292 HydrophobicContact CD1-CD2 4.14Å; I264-L292 HydrophobicContact CG2-CD2 4.2Å; I264-L292 WeakPolarHBondContact O-CA 3.35Å; I264-F293 PolarHBondContact O-N 3.27Å
265A98.6Very high92.7Very high0 Ų047.6 Ų47.60%025%0.245CC..EExtended strand (participates in β ladder)trans-86.7137.7175.100000110.5T187 L235 M236 L237 D238 F293T187-A265 HydrophobicContact CG2-CB 4.26Å; L235-A265 HydrophobicContact CB-CB 4Å; L235-A265 HydrophobicContact CD1-CB 4.2Å; M236-A265 PolarHBondContact O-N 2.86Å; L237-A265 WeakPolarHBondContact CB-O 3.29Å; L237-A265 WeakPolarHBondContact CG-O 3.4Å; D238-A265 WeakPolarHBondContact CA-O 3.22Å; D238-A265 HydrophobicContact CB-CB 3.85Å; D238-A265 PolarHBondContact N-O 3.45Å; D238-A265 WeakPolarHBondContact OD1-CB 3.42Å; A265-F293 CarbonylContact C-O 3.6Å; A265-F293 VanDerWaalsContact CA-O 3.22Å; A265-F293 WeakPolarHBondContact CA-O 3.44Å
266V98.3Very high92.4Very high4 Ų443.6 Ų43.62%0.02422%0.219CC..EExtended strand (participates in β ladder)trans-134.2142-176-64.70000113.3L237 D239 R241 L244 I264 L280 F293 A294 S295L237-V266 HydrophobicContact CD2-CG1 4.05Å; D239-V266 CarbonylContact O-C 3.57Å; D239-V266 WeakPolarHBondContact O-CA 3.47Å; R241-V266 HydrophobicContact CB-CB 4.35Å; R241-V266 HydrophobicContact CB-CG1 4.39Å; L244-V266 HydrophobicContact CD1-CG1 3.6Å; I264-V266 HydrophobicContact CG2-CG1 4.24Å; V266-L280 HydrophobicContact CG1-CD2 4.16Å; V266-L280 HydrophobicContact CG2-CD2 4.13Å; V266-F293 PolarHBondContact N-O 3.34Å; V266-A294 HydrophobicContact CG2-CB 4.14Å; V266-A294 VanDerWaalsContact O-CA 3.31Å; V266-A294 WeakPolarHBondContact O-CA 3.44Å; V266-S295 PolarHBondContact O-N 3.48Å; V266-S295 VanDerWaalsContact O-N 3.17Å
267H95.7Very high92.1Very high3 Ų343.7 Ų43.71%0.01422%0.218CC..EExtended strand (participates in β ladder)trans-109.2161.3175.2-59.7-171.6000111E191 D238 D239 R241 Y269 S295 E296E191-H267 IonicContact OE1-CE1 3.52Å; E191-H267 IonicContact OE1-ND1 3.68Å; E191-H267 PolarHBondContact OE1-ND1 2.77Å; D238-H267 PolarHBondContact O-CE1 3.08Å; D238-H267 VanDerWaalsContact O-CE1 3.27Å; D238-H267 PolarHBondContact O-NE2 3.33Å; D238-H267 IonicContact OD1-CD2 2.66Å; D238-H267 IonicContact OD1-NE2 3.78Å; D238-H267 PolarHBondContact OD1-NE2 3.41Å; D238-H267 VanDerWaalsContact OD1-NE2 3.1Å; D239-H267 PolarHBondContact O-N 2.54Å; R241-H267 PolarHBondContact N-O 3.29Å; H267-Y269 HydrophobicContact CB-CD2 4.29Å; H267-Y269 HydrophobicContact CB-CE2 4.38Å; H267-S295 PolarHBondContact CD2-OG 3.4Å; H267-S295 VanDerWaalsContact CD2-OG 3.24Å; H267-S295 PolarHBondContact NE2-OG 3.5Å; H267-E296 WeakPolarHBondContact CA-O 3.17Å; H267-E296 IonicContact CE1-OE2 2.82Å; H267-E296 PolarHBondContact CE1-OE2 3.1Å; H267-E296 IonicContact ND1-OE2 3.44Å; H267-E296 PolarHBondContact ND1-OE2 3.39Å; H267-E296 IonicContact NE2-OE2 3.06Å
268W90.3Very high91.9Very high34 Ų3446 Ų4613%0.12924%0.238CC..  trans-111.5-3.9-167.789.9-37.7000117.2L270 D271 A297 C298 V299 Q318 Y319W268-L270 PolarHBondContact O-N 3.23Å; W268-L270 VanDerWaalsContact O-N 3.13Å; W268-D271 VanDerWaalsContact CA-OD1 3.31Å; W268-D271 WeakPolarHBondContact CA-OD1 3.33Å; W268-D271 WeakPolarHBondContact O-CB 3.19Å; W268-D271 PolarHBondContact O-N 3.33Å; W268-D271 VanDerWaalsContact O-N 3.08Å; W268-A297 HydrophobicContact CB-CB 4.3Å; W268-A297 VanDerWaalsContact CD1-CA 3.43Å; W268-A297 VanDerWaalsContact CD1-CB 3.46Å; W268-A297 HydrophobicContact CD2-CB 3.82Å; W268-A297 HydrophobicContact CG-CB 3.6Å; W268-C298 VanDerWaalsContact CE2-O 3.25Å; W268-C298 WeakPolarHBondContact CZ2-O 3.28Å; W268-C298 PolarHBondContact NE1-O 3.24Å; W268-V299 HydrophobicContact CH2-CG1 3.58Å; W268-V299 HydrophobicContact CZ2-CG1 3.44Å; W268-V299 VanDerWaalsContact CZ2-CG1 3.44Å; W268-Q318 HydrophobicContact CH2-CB 4.07Å; W268-Q318 HydrophobicContact CZ3-CB 4.38Å; W268-Y319 HydrophobicContact CH2-CD2 4.24Å; W268-Y319 HydrophobicContact CH2-CE2 4.41Å; W268-Y319 HydrophobicContact CZ2-CE2 4.42Å
269Y82.8Confident91.8Very high34 Ų3444.8 Ų44.813%0.13323%0.227CC..THydrogen-bonded Turntrans-67-24.2-163.7-58.1-67.5000114.2H267 F272 E296 C298H267-Y269 HydrophobicContact CB-CD2 4.29Å; H267-Y269 HydrophobicContact CB-CE2 4.38Å; Y269-F272 WeakPolarHBondContact O-CE1 3.22Å; Y269-E296 HydrophobicContact CE2-CG 3.94Å; Y269-E296 WeakPolarHBondContact CE2-OE1 3.24Å; Y269-E296 VanDerWaalsContact OH-CD 3.31Å; Y269-E296 WeakPolarHBondContact OH-CG 3.43Å; Y269-E296 PolarHBondContact OH-OE1 3.38Å; Y269-C298 HydrophobicContact CE1-CB 4.17Å; Y269-C298 VanDerWaalsContact CE1-N 3.29Å; Y269-C298 WeakPolarHBondContact CE1-O 3.35Å; Y269-C298 WeakPolarHBondContact CE1-SG 3.19Å; Y269-C298 PolarHBondContact OH-N 2.99Å; Y269-C298 PolarHBondContact OH-SG 3.13Å
270L80.9Confident91.8Very high61 Ų6139.4 Ų39.432%0.31920%0.204SC..THydrogen-bonded Turntrans-105.619.1179-61.5-172.4000113.3Q240 L242 W268 F272 L273Q240-L270 HydrophobicContact CB-CB 4.4Å; Q240-L270 HydrophobicContact CB-CD1 4.34Å; Q240-L270 HydrophobicContact CG-CB 4.4Å; Q240-L270 HydrophobicContact CG-CD1 3.89Å; Q240-L270 HydrophobicContact CG-CG 4.01Å; L242-L270 HydrophobicContact CD1-CD1 4.11Å; L242-L270 HydrophobicContact CD2-CB 4.29Å; L242-L270 HydrophobicContact CD2-CD1 3.9Å; W268-L270 PolarHBondContact O-N 3.23Å; W268-L270 VanDerWaalsContact O-N 3.13Å; L270-F272 HydrophobicContact CD2-CE1 4.07Å; L270-F272 HydrophobicContact CD2-CZ 4.16Å; L270-F272 PolarHBondContact O-N 3.1Å; L270-F272 VanDerWaalsContact O-N 3.08Å; L270-L273 HydrophobicContact CB-CD1 4.11Å; L270-L273 HydrophobicContact CD1-CD1 4.29Å; L270-L273 HydrophobicContact CD2-CD1 4.24Å; L270-L273 HydrophobicContact CG-CD1 4.45Å; L270-L273 WeakPolarHBondContact O-CB 3.45Å; L270-L273 PolarHBondContact O-N 2.99Å
271D84.2Confident91.6Very high39 Ų3940.7 Ų40.721%0.20921%0.208CC..G310 helixtrans-58.3-26.5-176.3-92.126.4000114.6R241 W268 L273R241-D271 WeakPolarHBondContact CD-OD1 3.41Å; R241-D271 WeakPolarHBondContact CG-OD1 3.45Å; R241-D271 IonicContact CZ-OD1 3.66Å; R241-D271 IonicContact CZ-OD2 2.65Å; R241-D271 IonicContact NE-OD1 2.82Å; R241-D271 PolarHBondContact NE-OD1 2.97Å; R241-D271 IonicContact NE-OD2 2.94Å; R241-D271 PolarHBondContact NE-OD2 3.47Å; R241-D271 PolarHBondContact NH2-O 3.34Å; R241-D271 IonicContact NH2-OD1 3.84Å; R241-D271 IonicContact NH2-OD2 3.87Å; R241-D271 PolarHBondContact NH2-OD2 2.85Å; W268-D271 VanDerWaalsContact CA-OD1 3.31Å; W268-D271 WeakPolarHBondContact CA-OD1 3.33Å; W268-D271 WeakPolarHBondContact O-CB 3.19Å; W268-D271 PolarHBondContact O-N 3.33Å; W268-D271 VanDerWaalsContact O-N 3.08Å; D271-L273 PolarHBondContact O-N 2.91Å
272F80.3Confident91.5Very high128 Ų12842.7 Ų42.756%0.56122%0.217SC*.G310 helixtrans-69.4-15176.765.1-89000113.5Y269 L270Y269-F272 WeakPolarHBondContact O-CE1 3.22Å; L270-F272 HydrophobicContact CD2-CE1 4.07Å; L270-F272 HydrophobicContact CD2-CZ 4.16Å; L270-F272 PolarHBondContact O-N 3.1Å; L270-F272 VanDerWaalsContact O-N 3.08Å
273L77.8Confident91.5Very high104 Ų10439.5 Ų39.555%0.54520%0.202SC..G310 helixtrans-86.5-20.9-179.7-64.1-179.2000113.7L242 L270 D271L242-L273 HydrophobicContact CD1-CD1 4.22Å; L270-L273 HydrophobicContact CB-CD1 4.11Å; L270-L273 HydrophobicContact CD1-CD1 4.29Å; L270-L273 HydrophobicContact CD2-CD1 4.24Å; L270-L273 HydrophobicContact CG-CD1 4.45Å; L270-L273 WeakPolarHBondContact O-CB 3.45Å; L270-L273 PolarHBondContact O-N 2.99Å; D271-L273 PolarHBondContact O-N 2.91Å
274A81.7Confident91.5Very high22 Ų2241.9 Ų41.918%0.18221%0.213CC..SBendtrans-149.6140-179.100000111.1R241 T279R241-A274 PolarHBondContact NH1-O 3.37Å; R241-A274 PolarHBondContact NH2-O 3.1Å; A274-T279 HydrophobicContact CB-CG2 4.02Å
275P89.9Confident91.4Very high89 Ų8948.5 Ų48.558%0.57824%0.244SC*.  trans-71.1146.7173.829-33.5000111.8R241 K277 A278 T279R241-P275 PolarHBondContact NH1-O 3.15Å; P275-K277 PolarHBondContact O-N 2.56Å; P275-K277 VanDerWaalsContact O-N 3.14Å; P275-A278 HydrophobicContact CG-CB 4.06Å; P275-A278 PolarHBondContact O-N 3.31Å; P275-T279 PolarHBondContact O-OG1 3.17Å
276A92.6Very high91.4Very high6 Ų652.3 Ų52.35%0.0526%0.264CS..Hα-helixtrans-56.9-31.1178.400000112.9A278 T279 L280 R281 T325 Y329A276-A278 VanDerWaalsContact C-N 3.32Å; A276-A278 PolarHBondContact O-N 2.75Å; A276-T279 WeakPolarHBondContact CA-OG1 3.2Å; A276-T279 PolarHBondContact O-N 2.87Å; A276-T279 PolarHBondContact O-OG1 3.24Å; A276-L280 HydrophobicContact CB-CD1 4.14Å; A276-L280 PolarHBondContact O-N 3.33Å; A276-R281 PolarHBondContact O-N 3.24Å; A276-T325 HydrophobicContact CB-CG2 3.73Å; A276-Y329 HydrophobicContact CB-CD2 3.41Å; A276-Y329 VanDerWaalsContact CB-CD2 3.41Å; A276-Y329 HydrophobicContact CB-CE2 3.65Å; A276-Y329 HydrophobicContact CB-CG 4.13Å
277K91.8Very high91.4Very high102 Ų10253.7 Ų53.744%0.44327%0.269SS..Iπ-helixtrans-58.4-37.9174.8-170.5179.2174.7178.10113.5P275 T279 R281 Y329P275-K277 PolarHBondContact O-N 2.56Å; P275-K277 VanDerWaalsContact O-N 3.14Å; K277-T279 VanDerWaalsContact C-N 3.32Å; K277-R281 VanDerWaalsContact CG-CZ 3.43Å; K277-R281 WeakPolarHBondContact O-CB 3.38Å; K277-Y329 HydrophobicContact CB-CE1 4.11Å; K277-Y329 HydrophobicContact CG-CE1 4.44Å
278A94.5Very high91.5Very high50 Ų5056 Ų5641%0.41329%0.285SS..Iπ-helixtrans-82.9-12-178.700000113.2P275 A276P275-A278 HydrophobicContact CG-CB 4.06Å; P275-A278 PolarHBondContact O-N 3.31Å; A276-A278 VanDerWaalsContact C-N 3.32Å; A276-A278 PolarHBondContact O-N 2.75Å
279T97.2Very high91.7Very high4 Ų459.9 Ų59.93%0.02531%0.308CS..Iπ-helixtrans-116.3-76.6-171.847.80000110.2R241 A274 P275 A276 K277 T283R241-T279 PolarHBondContact NH1-OG1 3.47Å; R241-T279 WeakPolarHBondContact O-CB 3.26Å; R241-T279 WeakPolarHBondContact O-CG2 3.49Å; A274-T279 HydrophobicContact CB-CG2 4.02Å; P275-T279 PolarHBondContact O-OG1 3.17Å; A276-T279 WeakPolarHBondContact CA-OG1 3.2Å; A276-T279 PolarHBondContact O-N 2.87Å; A276-T279 PolarHBondContact O-OG1 3.24Å; K277-T279 VanDerWaalsContact C-N 3.32Å; T279-T283 WeakPolarHBondContact O-CB 3.07Å; T279-T283 PolarHBondContact O-N 3.21Å; T279-T283 PolarHBondContact O-OG1 3.17Å
280L96.9Very high92.4Very high0 Ų059.3 Ų59.30%031%0.308CS..Iπ-helixtrans-61.3-50-178.6-59.6179000112.3R241 L244 V266 A276 T283 H284 L292 V331R241-L280 HydrophobicContact CB-CD2 4.29Å; L244-L280 HydrophobicContact CD1-CD2 4.32Å; V266-L280 HydrophobicContact CG1-CD2 4.16Å; V266-L280 HydrophobicContact CG2-CD2 4.13Å; A276-L280 HydrophobicContact CB-CD1 4.14Å; A276-L280 PolarHBondContact O-N 3.33Å; L280-T283 PolarHBondContact O-N 3.3Å; L280-H284 PolarHBondContact O-N 2.83Å; L280-L292 HydrophobicContact CB-CD1 4.27Å; L280-L292 HydrophobicContact CD2-CD1 4.41Å; L280-L292 HydrophobicContact CD2-CD2 4.48Å; L280-L292 WeakPolarHBondContact O-CD1 3.36Å; L280-V331 HydrophobicContact CD1-CG2 3.83Å; L280-V331 HydrophobicContact CD2-CG2 4.25Å
281R95.8Very high93.1Very high92 Ų9257.4 Ų57.435%0.34730%0.298SS..Iπ-helixtrans-64.7-46.5-176.7-167.1-174.566.7152.16.9112.4A276 K277 T283 H284 H285 Y329A276-R281 PolarHBondContact O-N 3.24Å; K277-R281 VanDerWaalsContact CG-CZ 3.43Å; K277-R281 WeakPolarHBondContact O-CB 3.38Å; R281-T283 VanDerWaalsContact C-N 3.27Å; R281-T283 PolarHBondContact O-N 2.81Å; R281-H284 PolarHBondContact O-N 2.84Å; R281-H285 WeakPolarHBondContact O-CB 3.44Å; R281-H285 PolarHBondContact O-N 2.82Å; R281-Y329 HydrophobicContact CB-CD1 3.75Å; R281-Y329 HydrophobicContact CB-CE1 4.15Å; R281-Y329 HydrophobicContact CG-CD1 4.24Å
282E97.3Very high93.8Very high57 Ų5755.6 Ų55.627%0.26629%0.288SS..Hα-helixtrans-67.2-32.5179.2-60.5-43.6148.900111.9P245 H285 L286P245-E282 HydrophobicContact CG-CB 4.49Å; E282-H285 PolarHBondContact O-N 3.02Å; E282-H285 IonicContact OE2-ND1 3.57Å; E282-L286 VanDerWaalsContact O-CG 3.26Å; E282-L286 WeakPolarHBondContact O-CG 2.92Å; E282-L286 PolarHBondContact O-N 3.07Å
283T98.5Very high94.6Very high1 Ų149.6 Ų49.61%0.00626%0.262CS..Hα-helixtrans-64.6-46.7172.8-56.70000111.4L244 P245 A248 I264 T279 L280 R281 H285 L286 F287 L292L244-T283 WeakPolarHBondContact CB-OG1 3.32Å; L244-T283 HydrophobicContact CD1-CG2 4.36Å; L244-T283 HydrophobicContact CD2-CG2 4.1Å; P245-T283 WeakPolarHBondContact CA-OG1 3.37Å; P245-T283 WeakPolarHBondContact CB-OG1 3.35Å; A248-T283 HydrophobicContact CB-CG2 3.77Å; I264-T283 HydrophobicContact CD1-CG2 3.49Å; I264-T283 VanDerWaalsContact CD1-CG2 3.49Å; T279-T283 WeakPolarHBondContact O-CB 3.07Å; T279-T283 PolarHBondContact O-N 3.21Å; T279-T283 PolarHBondContact O-OG1 3.17Å; L280-T283 PolarHBondContact O-N 3.3Å; R281-T283 VanDerWaalsContact C-N 3.27Å; R281-T283 PolarHBondContact O-N 2.81Å; T283-H285 VanDerWaalsContact C-N 3.32Å; T283-H285 PolarHBondContact O-N 3.32Å; T283-L286 PolarHBondContact O-N 2.83Å; T283-F287 PolarHBondContact O-N 3.06Å; T283-L292 HydrophobicContact CG2-CD2 3.99Å
284H97.6Very high95.5Very high49 Ų4944.8 Ų44.823%0.22724%0.237CC..Hα-helixtrans-61.9-39.2175.6-177.368.2000112.1L280 R281 L286 F287 P288 L292 H330L280-H284 PolarHBondContact O-N 2.83Å; R281-H284 PolarHBondContact O-N 2.84Å; H284-L286 PolarHBondContact O-N 2.86Å; H284-F287 CarbonylContact O-C 3.37Å; H284-F287 PolarHBondContact O-N 2.9Å; H284-P288 PolarHBondContact CE1-O 2.95Å; H284-P288 WeakPolarHBondContact O-CA 3.45Å; H284-P288 WeakPolarHBondContact O-CB 2.92Å; H284-P288 WeakPolarHBondContact O-CD 3.41Å; H284-L292 HydrophobicContact CB-CD1 4.08Å; H284-H330 HydrophobicContact CB-CB 4.12Å; H284-H330 AromaticContact CD2-CD2 3.34Å; H284-H330 PolarHBondContact CD2-CD2 3.47Å; H284-H330 AromaticContact CD2-CE1 3.5Å; H284-H330 AromaticContact CD2-CG 3.28Å; H284-H330 AromaticContact CD2-ND1 3.39Å; H284-H330 PolarHBondContact CD2-ND1 3.26Å; H284-H330 AromaticContact CD2-NE2 3.5Å; H284-H330 AromaticContact CG-CD2 3.6Å; H284-H330 AromaticContact CG-CG 3.5Å; H284-H330 VanDerWaalsContact CG-CG 3.5Å; H284-H330 AromaticContact ND1-CG 3.97Å; H284-H330 AromaticContact NE2-CE1 3.75Å; H284-H330 AromaticContact NE2-CG 3.65Å; H284-H330 AromaticContact NE2-ND1 3.38Å; H284-H330 PolarHBondContact NE2-ND1 3.25Å
285H97.9Very high96.1Very high139 Ų13943.8 Ų43.864%0.64423%0.229SC*.Hα-helixtrans-62.8-41.7176.9-177.3-167.5000112R281 E282 T283R281-H285 WeakPolarHBondContact O-CB 3.44Å; R281-H285 PolarHBondContact O-N 2.82Å; E282-H285 PolarHBondContact O-N 3.02Å; E282-H285 IonicContact OE2-ND1 3.57Å; T283-H285 VanDerWaalsContact C-N 3.32Å; T283-H285 PolarHBondContact O-N 3.32Å
286L98.2Very high96.2Very high80 Ų8039.9 Ų39.942%0.41920%0.203SC..Hα-helixtrans-73.1-36.6178.3-67.7167.1000112.7P245 K249 E282 T283 H284P245-L286 HydrophobicContact CB-CD1 4.03Å; K249-L286 HydrophobicContact CD-CD1 4.35Å; K249-L286 HydrophobicContact CG-CD1 4.18Å; E282-L286 VanDerWaalsContact O-CG 3.26Å; E282-L286 WeakPolarHBondContact O-CG 2.92Å; E282-L286 PolarHBondContact O-N 3.07Å; T283-L286 PolarHBondContact O-N 2.83Å; H284-L286 PolarHBondContact O-N 2.86Å
287F98.2Very high96.1Very high33 Ų3339.6 Ų39.615%0.14520%0.201CC..  trans-132.462.8-173.2-54-72.2000111.7A248 K249 L252 T253 T283 H284 N289 T290A248-F287 HydrophobicContact CB-CD2 3.98Å; A248-F287 HydrophobicContact CB-CE2 3.9Å; K249-F287 HydrophobicContact CG-CE2 4.18Å; K249-F287 HydrophobicContact CG-CZ 4.34Å; L252-F287 HydrophobicContact CB-CD1 3.75Å; L252-F287 HydrophobicContact CB-CE1 3.56Å; L252-F287 HydrophobicContact CB-CE2 4.43Å; L252-F287 HydrophobicContact CB-CG 4.28Å; L252-F287 HydrophobicContact CB-CZ 3.94Å; L252-F287 HydrophobicContact CD1-CB 3.94Å; L252-F287 HydrophobicContact CD1-CD1 3.91Å; L252-F287 HydrophobicContact CD1-CD2 3.88Å; L252-F287 HydrophobicContact CD1-CE1 4.42Å; L252-F287 HydrophobicContact CD1-CE2 4.38Å; L252-F287 HydrophobicContact CD1-CG 3.62Å; T253-F287 HydrophobicContact CG2-CE1 4.46Å; T253-F287 HydrophobicContact CG2-CZ 4.17Å; T283-F287 PolarHBondContact O-N 3.06Å; H284-F287 CarbonylContact O-C 3.37Å; H284-F287 PolarHBondContact O-N 2.9Å; F287-N289 PolarHBondContact O-N 3.06Å; F287-N289 VanDerWaalsContact O-N 3.09Å; F287-T290 PolarHBondContact O-N 3.42Å
288P96.5Very high96Very high53 Ų5335 Ų3534%0.34418%0.181SC..THydrogen-bonded Turntrans-65.7-21.5-168.625.2-35.6000114.2H284H284-P288 PolarHBondContact CE1-O 2.95Å; H284-P288 WeakPolarHBondContact O-CA 3.45Å; H284-P288 WeakPolarHBondContact O-CB 2.92Å; H284-P288 WeakPolarHBondContact O-CD 3.41Å
289N94.6Very high95.7Very high114 Ų11432.8 Ų32.861%0.6116%0.162SC*.THydrogen-bonded Turntrans-91.5-6.1179.4-62.4-38.7000113.4F287F287-N289 PolarHBondContact O-N 3.06Å; F287-N289 VanDerWaalsContact O-N 3.09Å
290T97.8Very high95Very high23 Ų2332.7 Ų32.714%0.14116%0.162CC..SBendtrans-98.1114.7174.2-53.90000108.2L252 V261 I264 F287L252-T290 HydrophobicContact CD1-CG2 3.94Å; L252-T290 HydrophobicContact CD2-CG2 4.5Å; V261-T290 HydrophobicContact CG1-CG2 4.43Å; I264-T290 HydrophobicContact CD1-CG2 4.14Å; I264-T290 HydrophobicContact CG1-CG2 3.92Å; F287-T290 PolarHBondContact O-N 3.42Å
291M96.4Very high94Very high21 Ų2134.7 Ų34.710%0.10318%0.176CC..EExtended strand (participates in β ladder)trans-69.6146.1-173.164.788.4145.700111.8W184 L235 G263 I264 F293 V332W184-M291 HydrophobicContact CH2-CE 3.83Å; W184-M291 HydrophobicContact CZ2-CE 3.49Å; W184-M291 VanDerWaalsContact CZ2-CE 3.49Å; L235-M291 HydrophobicContact CD2-CE 3.76Å; L235-M291 HydrophobicContact CD2-SD 4.37Å; G263-M291 CarbonylContact C-O 3.49Å; G263-M291 WeakPolarHBondContact CA-O 3.15Å; I264-M291 PolarHBondContact N-O 2.79Å; M291-F293 HydrophobicContact CE-CB 4.4Å; M291-F293 HydrophobicContact SD-CB 3.77Å; M291-V332 HydrophobicContact CB-CG1 4.18Å; M291-V332 HydrophobicContact CB-CG2 4.14Å; M291-V332 HydrophobicContact CE-CG2 4.38Å; M291-V332 HydrophobicContact CG-CG2 4.37Å; M291-V332 HydrophobicContact SD-CG2 3.73Å
292L98Very high93.1Very high1 Ų133.2 Ų33.21%0.00517%0.173CC..EExtended strand (participates in β ladder)trans-99.1132.5171.7-68.7164.7000108.6L244 I264 L280 T283 H284 V331 V332L244-L292 HydrophobicContact CD1-CD2 4.28Å; I264-L292 HydrophobicContact CB-CD2 3.99Å; I264-L292 HydrophobicContact CD1-CD2 4.14Å; I264-L292 HydrophobicContact CG2-CD2 4.2Å; I264-L292 WeakPolarHBondContact O-CA 3.35Å; L280-L292 HydrophobicContact CB-CD1 4.27Å; L280-L292 HydrophobicContact CD2-CD1 4.41Å; L280-L292 HydrophobicContact CD2-CD2 4.48Å; L280-L292 WeakPolarHBondContact O-CD1 3.36Å; T283-L292 HydrophobicContact CG2-CD2 3.99Å; H284-L292 HydrophobicContact CB-CD1 4.08Å; L292-V331 HydrophobicContact CB-CG2 3.96Å; L292-V331 CarbonylContact O-C 3.47Å; L292-V331 VanDerWaalsContact O-CA 3.31Å; L292-V331 WeakPolarHBondContact O-CA 3.21Å; L292-V332 WeakPolarHBondContact O-CG2 3.49Å; L292-V332 PolarHBondContact O-N 2.98Å
293F97.6Very high92.1Very high1 Ų139.7 Ų39.70%0.00420%0.2CC..EExtended strand (participates in β ladder)trans-135.3125.2-178.7-177.4-95.5000110I74 L131 W184 L235 I264 A265 V266 M291 S295 V332 T335I74-F293 HydrophobicContact CD1-CE2 3.6Å; I74-F293 HydrophobicContact CD1-CZ 3.63Å; I74-F293 HydrophobicContact CG2-CZ 4.43Å; L131-F293 HydrophobicContact CD2-CD1 4.21Å; L131-F293 HydrophobicContact CD2-CE1 3.58Å; L131-F293 HydrophobicContact CD2-CZ 4.4Å; W184-F293 AromaticContact CH2-CD2 3.95Å; W184-F293 HydrophobicContact CH2-CD2 3.95Å; W184-F293 AromaticContact CH2-CE2 3.85Å; W184-F293 HydrophobicContact CH2-CE2 3.85Å; W184-F293 HydrophobicContact CH2-CG 4.35Å; W184-F293 HydrophobicContact CH2-CZ 4.18Å; W184-F293 HydrophobicContact CZ3-CE1 4.37Å; W184-F293 HydrophobicContact CZ3-CE2 4.13Å; W184-F293 HydrophobicContact CZ3-CZ 4.02Å; L235-F293 HydrophobicContact CD1-CB 4.48Å; L235-F293 HydrophobicContact CD1-CD1 4.18Å; I264-F293 PolarHBondContact O-N 3.27Å; A265-F293 CarbonylContact C-O 3.6Å; A265-F293 VanDerWaalsContact CA-O 3.22Å; A265-F293 WeakPolarHBondContact CA-O 3.44Å; V266-F293 PolarHBondContact N-O 3.34Å; M291-F293 HydrophobicContact CE-CB 4.4Å; M291-F293 HydrophobicContact SD-CB 3.77Å; F293-S295 PolarHBondContact O-N 3.22Å; F293-V332 HydrophobicContact CD2-CG2 4.24Å; F293-T335 WeakPolarHBondContact CE1-OG1 3.33Å; F293-T335 VanDerWaalsContact CZ-OG1 3.25Å; F293-T335 WeakPolarHBondContact CZ-OG1 3.22Å
294A96.9Very high91.1Very high4 Ų447.1 Ų47.13%0.03323%0.228CC..EExtended strand (participates in β ladder)trans-81.3107173.300000108.9V266 V331 G333 W334 T335V266-A294 HydrophobicContact CG2-CB 4.14Å; V266-A294 VanDerWaalsContact O-CA 3.31Å; V266-A294 WeakPolarHBondContact O-CA 3.44Å; A294-V331 HydrophobicContact CB-CG1 4.05Å; A294-G333 PolarHBondContact N-O 2.94Å; A294-W334 HydrophobicContact CB-CB 4.23Å; A294-W334 HydrophobicContact CB-CG 4.02Å; A294-W334 CarbonylContact O-C 3.46Å; A294-W334 VanDerWaalsContact O-CA 3.27Å; A294-W334 WeakPolarHBondContact O-CA 3.19Å; A294-T335 WeakPolarHBondContact O-CB 3.42Å; A294-T335 PolarHBondContact O-N 3.08Å; A294-T335 PolarHBondContact O-OG1 2.89Å
295S94.3Very high90.2Very high0 Ų047.1 Ų47.10%023%0.228CC..EExtended strand (participates in β ladder)trans-91.6-18.1-172.745.60000113.8D238 V266 H267 F293 T335D238-S295 WeakPolarHBondContact OD1-CB 3.44Å; D238-S295 PolarHBondContact OD1-OG 3.47Å; V266-S295 PolarHBondContact O-N 3.48Å; V266-S295 VanDerWaalsContact O-N 3.17Å; H267-S295 PolarHBondContact CD2-OG 3.4Å; H267-S295 VanDerWaalsContact CD2-OG 3.24Å; H267-S295 PolarHBondContact NE2-OG 3.5Å; F293-S295 PolarHBondContact O-N 3.22Å; S295-T335 VanDerWaalsContact O-CB 3.23Å; S295-T335 WeakPolarHBondContact O-CB 3.26Å; S295-T335 WeakPolarHBondContact O-CG2 3.48Å
296E92.3Very high89.5Confident8 Ų847 Ų474%0.03723%0.228CC..EExtended strand (participates in β ladder)trans-155.7137.9179.7174.2179.8165.800112.2H267 Y269 T335 W337H267-E296 WeakPolarHBondContact CA-O 3.17Å; H267-E296 IonicContact CE1-OE2 2.82Å; H267-E296 PolarHBondContact CE1-OE2 3.1Å; H267-E296 IonicContact ND1-OE2 3.44Å; H267-E296 PolarHBondContact ND1-OE2 3.39Å; H267-E296 IonicContact NE2-OE2 3.06Å; Y269-E296 HydrophobicContact CE2-CG 3.94Å; Y269-E296 WeakPolarHBondContact CE2-OE1 3.24Å; Y269-E296 VanDerWaalsContact OH-CD 3.31Å; Y269-E296 WeakPolarHBondContact OH-CG 3.43Å; Y269-E296 PolarHBondContact OH-OE1 3.38Å; E296-T335 CarbonylContact C-O 3.45Å; E296-T335 WeakPolarHBondContact CA-O 3.41Å; E296-W337 HydrophobicContact CB-CE3 3.92Å; E296-W337 HydrophobicContact CB-CZ3 3.93Å; E296-W337 VanDerWaalsContact CD-CD2 3.49Å; E296-W337 HydrophobicContact CG-CB 4.31Å; E296-W337 HydrophobicContact CG-CD2 3.7Å; E296-W337 HydrophobicContact CG-CE3 3.26Å; E296-W337 HydrophobicContact CG-CG 4.19Å; E296-W337 HydrophobicContact CG-CH2 4.21Å; E296-W337 HydrophobicContact CG-CZ3 3.53Å; E296-W337 WeakPolarHBondContact OE1-CZ2 3.37Å; E296-W337 WeakPolarHBondContact OE2-CH2 3.39Å; E296-W337 WeakPolarHBondContact OE2-CZ3 3.46Å
297A90.4Very high89.1Confident0 Ų044.5 Ų44.50%022%0.217CC..  trans-156.2137.7166.300000112W268 W334 T335 D336 W337W268-A297 HydrophobicContact CB-CB 4.3Å; W268-A297 VanDerWaalsContact CD1-CA 3.43Å; W268-A297 VanDerWaalsContact CD1-CB 3.46Å; W268-A297 HydrophobicContact CD2-CB 3.82Å; W268-A297 HydrophobicContact CG-CB 3.6Å; A297-W334 HydrophobicContact CB-CH2 3.44Å; A297-W334 VanDerWaalsContact CB-CH2 3.44Å; A297-W334 HydrophobicContact CB-CZ2 3.13Å; A297-W334 HydrophobicContact CB-CZ3 4.38Å; A297-T335 PolarHBondContact N-O 3.32Å; A297-T335 VanDerWaalsContact N-O 3.08Å; A297-D336 VanDerWaalsContact O-OD1 3.08Å; A297-W337 PolarHBondContact O-N 3.36Å
298C88Confident88.9Confident4 Ų443.2 Ų43.23%0.02721%0.212CC..  trans-147.6162.6165.2760000113.7W268 Y269 W337 V354W268-C298 VanDerWaalsContact CE2-O 3.25Å; W268-C298 WeakPolarHBondContact CZ2-O 3.28Å; W268-C298 PolarHBondContact NE1-O 3.24Å; Y269-C298 HydrophobicContact CE1-CB 4.17Å; Y269-C298 VanDerWaalsContact CE1-N 3.29Å; Y269-C298 WeakPolarHBondContact CE1-O 3.35Å; Y269-C298 WeakPolarHBondContact CE1-SG 3.19Å; Y269-C298 PolarHBondContact OH-N 2.99Å; Y269-C298 PolarHBondContact OH-SG 3.13Å; C298-W337 HydrophobicContact CB-CB 3.73Å; C298-W337 HydrophobicContact CB-CG 4.45Å; C298-V354 HydrophobicContact CB-CG2 4.28Å
299V89.5Confident88.8Confident4 Ų446.2 Ų46.22%0.02422%0.217CC..SBendtrans-109162.2174-70.70000110.9W268 S301 R315 Q318 Y319 D355 M372W268-V299 HydrophobicContact CH2-CG1 3.58Å; W268-V299 HydrophobicContact CZ2-CG1 3.44Å; W268-V299 VanDerWaalsContact CZ2-CG1 3.44Å; V299-S301 VanDerWaalsContact C-N 3.32Å; V299-R315 HydrophobicContact CB-CG 4.24Å; V299-R315 HydrophobicContact CG1-CG 4.44Å; V299-R315 HydrophobicContact CG2-CB 4.11Å; V299-R315 VanDerWaalsContact CG2-CD 3.44Å; V299-R315 HydrophobicContact CG2-CG 3.75Å; V299-Q318 HydrophobicContact CG1-CB 4.49Å; V299-Y319 HydrophobicContact CB-CE2 4.47Å; V299-Y319 HydrophobicContact CG1-CD2 4.32Å; V299-Y319 HydrophobicContact CG1-CE2 3.89Å; V299-Y319 HydrophobicContact CG2-CE2 3.95Å; V299-D355 HydrophobicContact CG2-CB 3.74Å; V299-D355 PolarHBondContact O-N 3.09Å; V299-M372 HydrophobicContact CG2-CE 4.38Å; V299-M372 HydrophobicContact CG2-SD 3.45Å; V299-M372 WeakPolarHBondContact CG2-SD 3.13Å
300G81.4Confident88.9Confident2 Ų245.5 Ų45.52%0.02121%0.212CC..SBendtrans82.39.7-178.400000114.3E305G300-E305 WeakPolarHBondContact CA-OE2 3.5Å; G300-E305 PolarHBondContact N-OE2 3.33Å; G300-E305 VanDerWaalsContact N-OE2 3.16Å
301S76.1Confident88.9Confident43 Ų4346.9 Ų46.930%0.30123%0.231SC..  trans-81-13176.5570000114.3V299V299-S301 VanDerWaalsContact C-N 3.32Å
302K77.8Confident89Confident61 Ų6146.5 Ų46.527%0.26523%0.23SC..SBendtrans-82.9138.5-179.8-54.6-173.2-161.7145.30110W304 E305K302-W304 HydrophobicContact CB-CD2 3.99Å; K302-W304 HydrophobicContact CB-CE3 4.15Å; K302-W304 HydrophobicContact CB-CH2 4.14Å; K302-W304 HydrophobicContact CB-CZ2 3.96Å; K302-W304 HydrophobicContact CB-CZ3 4.22Å; K302-W304 HydrophobicContact CD-CH2 3.74Å; K302-W304 HydrophobicContact CD-CZ2 3.23Å; K302-W304 HydrophobicContact CG-CH2 4.35Å; K302-W304 HydrophobicContact CG-CZ2 4.15Å; K302-W304 PolarHBondContact O-N 3Å; K302-E305 HydrophobicContact CB-CB 4.49Å; K302-E305 HydrophobicContact CB-CG 4.08Å; K302-E305 WeakPolarHBondContact CD-OE1 3.14Å; K302-E305 IonicContact NZ-OE1 3.41Å; K302-E305 PolarHBondContact NZ-OE1 2.95Å; K302-E305 PolarHBondContact O-N 2.89Å
303F76.4Confident89Confident192 Ų19251 Ų5184%0.84225%0.247SC*.THydrogen-bonded Turntrans-59-18.7-17472.2-101.2000115.4
304W76.5Confident88.9Confident157 Ų15755 Ų5560%0.59527%0.269SS*.THydrogen-bonded Turntrans-98.8-3.117862.682.8000113.7K302K302-W304 HydrophobicContact CB-CD2 3.99Å; K302-W304 HydrophobicContact CB-CE3 4.15Å; K302-W304 HydrophobicContact CB-CH2 4.14Å; K302-W304 HydrophobicContact CB-CZ2 3.96Å; K302-W304 HydrophobicContact CB-CZ3 4.22Å; K302-W304 HydrophobicContact CD-CH2 3.74Å; K302-W304 HydrophobicContact CD-CZ2 3.23Å; K302-W304 HydrophobicContact CG-CH2 4.35Å; K302-W304 HydrophobicContact CG-CZ2 4.15Å; K302-W304 PolarHBondContact O-N 3Å
305E78.3Confident88.9Confident50 Ų5055 Ų5523%0.23427%0.268CS..SBendtrans-95.2140.1176.9-67.9-179.7-169.600109.7G300 K302 S307 R315G300-E305 WeakPolarHBondContact CA-OE2 3.5Å; G300-E305 PolarHBondContact N-OE2 3.33Å; G300-E305 VanDerWaalsContact N-OE2 3.16Å; K302-E305 HydrophobicContact CB-CB 4.49Å; K302-E305 HydrophobicContact CB-CG 4.08Å; K302-E305 WeakPolarHBondContact CD-OE1 3.14Å; K302-E305 IonicContact NZ-OE1 3.41Å; K302-E305 PolarHBondContact NZ-OE1 2.95Å; K302-E305 PolarHBondContact O-N 2.89Å; E305-S307 PolarHBondContact O-N 2.98Å; E305-R315 IonicContact OE2-NH2 2.77Å
306Q83.3Confident89Confident136 Ų13655 Ų5564%0.63627%0.268SS*.  trans-64.9130.1165.4-179.7-177.64.200108.9V308 R309 R315Q306-V308 WeakPolarHBondContact CG-O 3.46Å; Q306-V308 PolarHBondContact NE2-O 3.42Å; Q306-R309 HydrophobicContact CB-CG 4.1Å; Q306-R309 HydrophobicContact CG-CG 4.29Å; Q306-R315 PolarHBondContact O-NH1 2.93Å; Q306-R315 PolarHBondContact O-NH2 3.19Å
307S89.6Confident89.3Confident27 Ų2755.2 Ų55.219%0.18927%0.269CS..SBendtrans-55.9-59.9-177.2-56.10000112.3E305 R315 F353 V354 D355E305-S307 PolarHBondContact O-N 2.98Å; S307-R315 PolarHBondContact O-NH1 3.31Å; S307-R315 PolarHBondContact O-NH2 3.31Å; S307-F353 WeakPolarHBondContact CB-O 3.31Å; S307-F353 VanDerWaalsContact OG-CB 3.27Å; S307-F353 WeakPolarHBondContact OG-CB 3.36Å; S307-F353 PolarHBondContact OG-O 2.88Å; S307-V354 CarbonylContact O-C 3.46Å; S307-D355 WeakPolarHBondContact O-CA 3.04Å; S307-D355 WeakPolarHBondContact O-CB 3.37Å; S307-D355 PolarHBondContact O-N 3.43Å; S307-D355 VanDerWaalsContact O-N 3.11Å
308V94.1Very high89.6Confident7 Ų758.8 Ų58.84%0.04229%0.285CS..  trans-104.6129.4176.5176.60000111.6Q306 L310 P343 G345 I359Q306-V308 WeakPolarHBondContact CG-O 3.46Å; Q306-V308 PolarHBondContact NE2-O 3.42Å; V308-L310 HydrophobicContact CG1-CD2 4.22Å; V308-L310 HydrophobicContact CG1-CG 4.31Å; V308-P343 WeakPolarHBondContact CB-O 3.28Å; V308-G345 VanDerWaalsContact CG2-CA 3.41Å; V308-I359 HydrophobicContact CB-CD1 4.46Å; V308-I359 HydrophobicContact CG1-CD1 3.75Å; V308-I359 HydrophobicContact CG1-CG1 3.8Å; V308-I359 HydrophobicContact CG1-CG2 4.42Å; V308-I359 HydrophobicContact CG2-CD1 3.79Å
309R96.1Very high90Very high116 Ų11658.6 Ų58.644%0.43828%0.284SS..  trans-12695.3171.9-68.5-176.969.1-162.3-2.3109.7Q306 G311 S312 R315 D355 Q370Q306-R309 HydrophobicContact CB-CG 4.1Å; Q306-R309 HydrophobicContact CG-CG 4.29Å; R309-G311 PolarHBondContact O-N 2.71Å; R309-S312 WeakPolarHBondContact O-CB 3.39Å; R309-S312 PolarHBondContact O-N 2.92Å; R309-R315 VanDerWaalsContact N-NH1 3.2Å; R309-D355 PolarHBondContact N-OD2 2.57Å; R309-D355 VanDerWaalsContact N-OD2 3.15Å; R309-Q370 PolarHBondContact O-NE2 2.94Å
310L96.5Very high90.4Very high98 Ų9858.4 Ų58.451%0.51328%0.283SS..THydrogen-bonded Turntrans-58.7124.9-179.9-68.4177.2000111.2V308 I359 Y368V308-L310 HydrophobicContact CG1-CD2 4.22Å; V308-L310 HydrophobicContact CG1-CG 4.31Å; L310-I359 HydrophobicContact CD2-CB 3.9Å; L310-I359 HydrophobicContact CD2-CG1 3.89Å; L310-I359 HydrophobicContact CD2-CG2 4.05Å; L310-Y368 HydrophobicContact CD1-CD2 4.43Å; L310-Y368 HydrophobicContact CD2-CD2 4.03Å; L310-Y368 HydrophobicContact CD2-CG 4.26Å
311G96.9Very high91.2Very high52 Ų5261 Ų6154%0.53630%0.295SS..THydrogen-bonded Turntrans79.612178.300000115.7R309 W313R309-G311 PolarHBondContact O-N 2.71Å; G311-W313 PolarHBondContact O-N 2.94Å
312S98Very high92.1Very high13 Ų1359.3 Ų59.39%0.09128%0.283CS..  trans-69.299.7-176.1-178.80000113.5R309 D314 R315 G316R309-S312 WeakPolarHBondContact O-CB 3.39Å; R309-S312 PolarHBondContact O-N 2.92Å; S312-D314 VanDerWaalsContact C-N 3.32Å; S312-D314 PolarHBondContact O-N 2.88Å; S312-R315 PolarHBondContact O-N 3.28Å; S312-G316 PolarHBondContact O-N 2.87Å
313W97.9Very high93Very high96 Ų9656.5 Ų56.536%0.36427%0.271SS..Hα-helixtrans-59.8-39.3176.4-167.3-104.4000112.8G311 R315 G316 M317 P371 H375 Y443G311-W313 PolarHBondContact O-N 2.94Å; W313-R315 PolarHBondContact O-N 3.26Å; W313-G316 WeakPolarHBondContact O-CA 3.43Å; W313-G316 PolarHBondContact O-N 2.93Å; W313-M317 PolarHBondContact O-N 3.08Å; W313-P371 HydrophobicContact CE3-CB 4.03Å; W313-P371 HydrophobicContact CE3-CG 4.36Å; W313-H375 AromaticContact CE2-NE2 3.69Å; W313-H375 AromaticContact CH2-NE2 3.62Å; W313-H375 AromaticContact CZ2-NE2 3.49Å; W313-H375 WeakPolarHBondContact CZ2-NE2 3.4Å; W313-H375 AromaticContact CZ3-NE2 3.93Å; W313-Y443 VanDerWaalsContact CE2-O 3.22Å; W313-Y443 WeakPolarHBondContact CZ2-O 3.43Å; W313-Y443 PolarHBondContact NE1-O 3.44Å; W313-Y443 VanDerWaalsContact NE1-O 3.14Å
314D96.8Very high94Very high85 Ų8547.4 Ų47.446%0.45523%0.231SC..Hα-helixtrans-57.7-32.6177.2-66.6-23.6000113.2S312 M317 Q318S312-D314 VanDerWaalsContact C-N 3.32Å; S312-D314 PolarHBondContact O-N 2.88Å; D314-M317 HydrophobicContact CB-CE 4.46Å; D314-M317 WeakPolarHBondContact OD1-CE 3.15Å; D314-Q318 VanDerWaalsContact O-CG 3.3Å; D314-Q318 WeakPolarHBondContact O-CG 3.45Å; D314-Q318 PolarHBondContact O-N 2.82Å; D314-Q318 PolarHBondContact O-NE2 3.38Å
315R96.4Very high95Very high5 Ų541.3 Ų41.32%0.01921%0.211CC..Hα-helixtrans-73.9-39.2176.9-77.6-177.4162.8173.1-2.1110.9V299 E305 Q306 S307 R309 S312 W313 Q318 Y319 D355 M372V299-R315 HydrophobicContact CB-CG 4.24Å; V299-R315 HydrophobicContact CG1-CG 4.44Å; V299-R315 HydrophobicContact CG2-CB 4.11Å; V299-R315 VanDerWaalsContact CG2-CD 3.44Å; V299-R315 HydrophobicContact CG2-CG 3.75Å; E305-R315 IonicContact OE2-NH2 2.77Å; Q306-R315 PolarHBondContact O-NH1 2.93Å; Q306-R315 PolarHBondContact O-NH2 3.19Å; S307-R315 PolarHBondContact O-NH1 3.31Å; S307-R315 PolarHBondContact O-NH2 3.31Å; R309-R315 VanDerWaalsContact N-NH1 3.2Å; S312-R315 PolarHBondContact O-N 3.28Å; W313-R315 PolarHBondContact O-N 3.26Å; R315-Q318 PolarHBondContact O-N 2.9Å; R315-Y319 WeakPolarHBondContact O-CD2 3.46Å; R315-Y319 PolarHBondContact O-N 3.21Å; R315-D355 VanDerWaalsContact CD-OD2 3.29Å; R315-D355 WeakPolarHBondContact CD-OD2 3.35Å; R315-D355 IonicContact CZ-OD2 3.44Å; R315-D355 IonicContact NE-OD2 3.23Å; R315-D355 VanDerWaalsContact NH1-CG 3.33Å; R315-D355 IonicContact NH1-OD2 3.77Å; R315-D355 PolarHBondContact NH1-OD2 3.41Å; R315-M372 HydrophobicContact CB-CG 3.86Å; R315-M372 HydrophobicContact CB-SD 3.84Å
316G97.1Very high95.8Very high0 Ų039.4 Ų39.40%020%0.202CC..Hα-helixtrans-56.5-49.7168.600000112.1S312 W313 Q318 Y319 S320 H375S312-G316 PolarHBondContact O-N 2.87Å; W313-G316 WeakPolarHBondContact O-CA 3.43Å; W313-G316 PolarHBondContact O-N 2.93Å; G316-Q318 VanDerWaalsContact C-N 3.33Å; G316-Q318 PolarHBondContact O-N 3.08Å; G316-Y319 WeakPolarHBondContact O-CB 3.43Å; G316-Y319 PolarHBondContact O-N 3.42Å; G316-S320 PolarHBondContact O-N 3.36Å; G316-S320 VanDerWaalsContact O-N 3.13Å; G316-S320 PolarHBondContact O-OG 2.78Å; G316-H375 VanDerWaalsContact C-ND1 3.29Å; G316-H375 VanDerWaalsContact CA-CD2 3.48Å; G316-H375 WeakPolarHBondContact CA-CD2 3.47Å; G316-H375 WeakPolarHBondContact O-CB 3.15Å; G316-H375 PolarHBondContact O-ND1 2.81Å; G316-H375 VanDerWaalsContact O-ND1 3.08Å
317M98.2Very high96.4Very high12 Ų1233.4 Ų33.46%0.05917%0.174CC..Hα-helixtrans-60.4-39.1178.3-67.3-167-65.800112.8W313 D314 S320 H321 L417 R419 Y443W313-M317 PolarHBondContact O-N 3.08Å; D314-M317 HydrophobicContact CB-CE 4.46Å; D314-M317 WeakPolarHBondContact OD1-CE 3.15Å; M317-S320 PolarHBondContact O-OG 2.62Å; M317-H321 WeakPolarHBondContact O-CB 3.32Å; M317-H321 PolarHBondContact O-N 3.13Å; M317-L417 HydrophobicContact CG-CD1 4.31Å; M317-R419 HydrophobicContact CB-CG 4.17Å; M317-R419 HydrophobicContact CG-CG 4.34Å; M317-R419 HydrophobicContact SD-CB 3.92Å; M317-R419 HydrophobicContact SD-CG 3.86Å; M317-Y443 HydrophobicContact CE-CD1 4.03Å; M317-Y443 HydrophobicContact CE-CE1 4.34Å; M317-Y443 HydrophobicContact SD-CD1 3.94Å
318Q96.3Very high96.7Very high74 Ų7435.4 Ų35.435%0.34618%0.183SC..Hα-helixtrans-59.6-44.6175.2-78173.276.300112.2W268 V299 D314 R315 G316 S322W268-Q318 HydrophobicContact CH2-CB 4.07Å; W268-Q318 HydrophobicContact CZ3-CB 4.38Å; V299-Q318 HydrophobicContact CG1-CB 4.49Å; D314-Q318 VanDerWaalsContact O-CG 3.3Å; D314-Q318 WeakPolarHBondContact O-CG 3.45Å; D314-Q318 PolarHBondContact O-N 2.82Å; D314-Q318 PolarHBondContact O-NE2 3.38Å; R315-Q318 PolarHBondContact O-N 2.9Å; G316-Q318 VanDerWaalsContact C-N 3.33Å; G316-Q318 PolarHBondContact O-N 3.08Å; Q318-S322 VanDerWaalsContact O-CB 3.31Å; Q318-S322 WeakPolarHBondContact O-CB 3.22Å; Q318-S322 PolarHBondContact O-N 2.97Å
319Y96.8Very high96.9Very high0 Ų038.2 Ų38.20%019%0.193CC..Hα-helixtrans-59.8-57.6176.5-88.5-121.5000111W268 V299 R315 G316 H321 S322 I323 W334 D336 P357 M372 L376W268-Y319 HydrophobicContact CH2-CD2 4.24Å; W268-Y319 HydrophobicContact CH2-CE2 4.41Å; W268-Y319 HydrophobicContact CZ2-CE2 4.42Å; V299-Y319 HydrophobicContact CB-CE2 4.47Å; V299-Y319 HydrophobicContact CG1-CD2 4.32Å; V299-Y319 HydrophobicContact CG1-CE2 3.89Å; V299-Y319 HydrophobicContact CG2-CE2 3.95Å; R315-Y319 WeakPolarHBondContact O-CD2 3.46Å; R315-Y319 PolarHBondContact O-N 3.21Å; G316-Y319 WeakPolarHBondContact O-CB 3.43Å; G316-Y319 PolarHBondContact O-N 3.42Å; Y319-H321 VanDerWaalsContact C-N 3.31Å; Y319-H321 PolarHBondContact O-N 2.97Å; Y319-S322 WeakPolarHBondContact O-CB 3.49Å; Y319-S322 PolarHBondContact O-N 3.31Å; Y319-S322 VanDerWaalsContact O-N 3.14Å; Y319-I323 WeakPolarHBondContact O-CD1 3.06Å; Y319-I323 VanDerWaalsContact O-CG1 3.28Å; Y319-I323 WeakPolarHBondContact O-CG1 3.35Å; Y319-I323 PolarHBondContact O-N 3.48Å; Y319-W334 AromaticContact CD1-CH2 3.47Å; Y319-W334 HydrophobicContact CD1-CH2 3.47Å; Y319-W334 VanDerWaalsContact CD1-CH2 3.47Å; Y319-W334 HydrophobicContact CD1-CZ2 4.33Å; Y319-W334 AromaticContact CD1-CZ3 3.99Å; Y319-W334 HydrophobicContact CD1-CZ3 3.99Å; Y319-W334 AromaticContact CE1-CH2 3.48Å; Y319-W334 HydrophobicContact CE1-CH2 3.48Å; Y319-W334 VanDerWaalsContact CE1-CH2 3.48Å; Y319-W334 AromaticContact CE1-CZ3 3.99Å; Y319-W334 HydrophobicContact CE1-CZ3 3.99Å; Y319-W334 HydrophobicContact CG-CH2 4.24Å; Y319-D336 HydrophobicContact CE1-CB 4.45Å; Y319-D336 WeakPolarHBondContact CE1-OD1 3.25Å; Y319-D336 PolarHBondContact OH-OD1 2.84Å; Y319-P357 HydrophobicContact CE1-CG 4.29Å; Y319-M372 HydrophobicContact CD1-CB 4.38Å; Y319-M372 HydrophobicContact CD2-CB 4.37Å; Y319-M372 HydrophobicContact CD2-CG 3.84Å; Y319-M372 HydrophobicContact CD2-SD 3.92Å; Y319-M372 HydrophobicContact CE1-CB 4.43Å; Y319-M372 HydrophobicContact CE2-CB 4.42Å; Y319-M372 HydrophobicContact CE2-CG 3.89Å; Y319-M372 HydrophobicContact CE2-SD 3.35Å; Y319-M372 WeakPolarHBondContact CE2-SD 3.25Å; Y319-M372 HydrophobicContact CG-CB 4.34Å; Y319-M372 HydrophobicContact CG-CG 4.26Å; Y319-L376 HydrophobicContact CD1-CD1 3.53Å; Y319-L376 HydrophobicContact CD1-CD2 4Å; Y319-L376 HydrophobicContact CD1-CG 3.67Å; Y319-L376 HydrophobicContact CE1-CD1 3.62Å; Y319-L376 HydrophobicContact CE1-CG 4.27Å
320S97.4Very high96.8Very high0 Ų035.7 Ų35.70%019%0.186CC..Hα-helixtrans-62.9-36-177.749.40000113.5G316 M317 I323 I324 H375 L417G316-S320 PolarHBondContact O-N 3.36Å; G316-S320 VanDerWaalsContact O-N 3.13Å; G316-S320 PolarHBondContact O-OG 2.78Å; M317-S320 PolarHBondContact O-OG 2.62Å; S320-I323 PolarHBondContact O-N 3.25Å; S320-I324 VanDerWaalsContact O-CG1 3.29Å; S320-I324 WeakPolarHBondContact O-CG1 3.35Å; S320-I324 PolarHBondContact O-N 2.91Å; S320-H375 WeakPolarHBondContact CB-ND1 3.44Å; S320-H375 PolarHBondContact OG-ND1 3.31Å; S320-L417 WeakPolarHBondContact OG-CD1 3.28Å; S320-L417 VanDerWaalsContact OG-CD2 3.27Å; S320-L417 WeakPolarHBondContact OG-CD2 3.17Å
321H97.8Very high96.8Very high57 Ų5731.2 Ų31.226%0.26416%0.163SC..Hα-helixtrans-64.6-43175.4178.169.4000111.3M317 Y319 T325 D401 L417 R419M317-H321 WeakPolarHBondContact O-CB 3.32Å; M317-H321 PolarHBondContact O-N 3.13Å; Y319-H321 VanDerWaalsContact C-N 3.31Å; Y319-H321 PolarHBondContact O-N 2.97Å; H321-T325 WeakPolarHBondContact O-CB 3.14Å; H321-T325 PolarHBondContact O-N 2.83Å; H321-T325 PolarHBondContact O-OG1 3.1Å; H321-D401 IonicContact CE1-OD1 3.31Å; H321-D401 IonicContact CE1-OD2 3.33Å; H321-D401 IonicContact CG-OD2 2.93Å; H321-D401 IonicContact ND1-OD1 3.98Å; H321-D401 PolarHBondContact ND1-OD1 3.15Å; H321-D401 IonicContact ND1-OD2 3.67Å; H321-D401 PolarHBondContact ND1-OD2 3.2Å; H321-L417 HydrophobicContact CB-CD2 3.89Å; H321-R419 PolarHBondContact CE1-NH2 3.26Å; H321-R419 VanDerWaalsContact CE1-NH2 3.33Å; H321-R419 PolarHBondContact ND1-NE 2.98Å; H321-R419 PolarHBondContact ND1-NH2 2.91Å
322S96.7Very high96.7Very high7 Ų729.5 Ų29.55%0.04914%0.142CC..Hα-helixtrans-61.2-47.4174.6179.30000111.3Q318 Y319 I324 T325 N326 W334Q318-S322 VanDerWaalsContact O-CB 3.31Å; Q318-S322 WeakPolarHBondContact O-CB 3.22Å; Q318-S322 PolarHBondContact O-N 2.97Å; Y319-S322 WeakPolarHBondContact O-CB 3.49Å; Y319-S322 PolarHBondContact O-N 3.31Å; Y319-S322 VanDerWaalsContact O-N 3.14Å; S322-I324 PolarHBondContact O-N 3.06Å; S322-T325 WeakPolarHBondContact O-CB 3.37Å; S322-T325 PolarHBondContact O-N 3.33Å; S322-N326 WeakPolarHBondContact O-CB 3.31Å; S322-N326 PolarHBondContact O-N 3.27Å; S322-N326 PolarHBondContact O-ND2 2.88Å; S322-N326 PolarHBondContact OG-ND2 3.26Å; S322-W334 PolarHBondContact OG-NE1 2.87Å
323I96.4Very high96.3Very high3 Ų329 Ų292%0.01514%0.139CC..Hα-helixtrans-61-46.7179.6-64.1152.6000111.1M21 Y319 S320 T325 N326 L327 W334 L376 F379M21-I323 HydrophobicContact CE-CD1 3.38Å; M21-I323 HydrophobicContact CE-CG1 4Å; M21-I323 HydrophobicContact CE-CG2 3.99Å; M21-I323 HydrophobicContact SD-CD1 3.47Å; M21-I323 WeakPolarHBondContact SD-CD1 3.37Å; M21-I323 HydrophobicContact SD-CG1 3.65Å; M21-I323 HydrophobicContact SD-CG2 4.26Å; Y319-I323 WeakPolarHBondContact O-CD1 3.06Å; Y319-I323 VanDerWaalsContact O-CG1 3.28Å; Y319-I323 WeakPolarHBondContact O-CG1 3.35Å; Y319-I323 PolarHBondContact O-N 3.48Å; S320-I323 PolarHBondContact O-N 3.25Å; I323-T325 VanDerWaalsContact C-N 3.33Å; I323-T325 PolarHBondContact O-N 2.85Å; I323-N326 PolarHBondContact O-N 3.46Å; I323-L327 HydrophobicContact CG2-CD1 3.95Å; I323-L327 HydrophobicContact CG2-CG 4.4Å; I323-L327 WeakPolarHBondContact O-CB 3.47Å; I323-L327 VanDerWaalsContact O-CG 3.31Å; I323-L327 WeakPolarHBondContact O-CG 3.48Å; I323-L327 PolarHBondContact O-N 3.27Å; I323-W334 HydrophobicContact CG1-CD2 3.81Å; I323-W334 HydrophobicContact CG1-CE3 4.3Å; I323-W334 HydrophobicContact CG1-CG 3.91Å; I323-L376 HydrophobicContact CD1-CD2 3.89Å; I323-F379 HydrophobicContact CB-CD2 4.46Å; I323-F379 HydrophobicContact CB-CE1 4.33Å; I323-F379 HydrophobicContact CB-CE2 4.25Å; I323-F379 HydrophobicContact CB-CZ 4.17Å; I323-F379 HydrophobicContact CD1-CD2 3.94Å; I323-F379 HydrophobicContact CD1-CE2 4.02Å; I323-F379 HydrophobicContact CG2-CB 4.42Å; I323-F379 HydrophobicContact CG2-CD1 3.57Å; I323-F379 HydrophobicContact CG2-CD2 4.04Å; I323-F379 HydrophobicContact CG2-CE1 3.71Å; I323-F379 HydrophobicContact CG2-CE2 4.18Å; I323-F379 HydrophobicContact CG2-CG 3.76Å; I323-F379 HydrophobicContact CG2-CZ 4.03Å
324I97.9Very high96.2Very high1 Ų124.8 Ų24.81%0.00512%0.123CC..Hα-helixtrans-59.2-46.8176.1-69.8165.2000110.2S320 S322 N326 L327 L328 F379 D401 V403 L417S320-I324 VanDerWaalsContact O-CG1 3.29Å; S320-I324 WeakPolarHBondContact O-CG1 3.35Å; S320-I324 PolarHBondContact O-N 2.91Å; S322-I324 PolarHBondContact O-N 3.06Å; I324-N326 PolarHBondContact O-N 2.82Å; I324-L327 PolarHBondContact O-N 3.43Å; I324-L328 HydrophobicContact CG2-CD1 3.73Å; I324-L328 HydrophobicContact CG2-CG 4.21Å; I324-L328 WeakPolarHBondContact O-CB 3.46Å; I324-L328 WeakPolarHBondContact O-CG 3.44Å; I324-L328 PolarHBondContact O-N 3.47Å; I324-F379 HydrophobicContact CD1-CE1 4.45Å; I324-F379 HydrophobicContact CD1-CZ 4.05Å; I324-F379 HydrophobicContact CG1-CE1 3.72Å; I324-F379 HydrophobicContact CG1-CZ 3.68Å; I324-D401 HydrophobicContact CD1-CB 3.78Å; I324-D401 HydrophobicContact CG2-CB 4.11Å; I324-V403 HydrophobicContact CG1-CG1 4.08Å; I324-V403 HydrophobicContact CG2-CB 4.36Å; I324-L417 HydrophobicContact CD1-CB 3.81Å; I324-L417 HydrophobicContact CD1-CD2 4.38Å
325T97.1Very high95.9Very high29 Ų2920.7 Ų20.718%0.17810%0.101CC..Hα-helixtrans-58.7-48.2177.9-61.60000111.4A276 H321 S322 I323 L328 Y329A276-T325 HydrophobicContact CB-CG2 3.73Å; H321-T325 WeakPolarHBondContact O-CB 3.14Å; H321-T325 PolarHBondContact O-N 2.83Å; H321-T325 PolarHBondContact O-OG1 3.1Å; S322-T325 WeakPolarHBondContact O-CB 3.37Å; S322-T325 PolarHBondContact O-N 3.33Å; I323-T325 VanDerWaalsContact C-N 3.33Å; I323-T325 PolarHBondContact O-N 2.85Å; T325-L328 PolarHBondContact O-N 3.38Å; T325-Y329 HydrophobicContact CG2-CD2 3.8Å; T325-Y329 HydrophobicContact CG2-CE2 4.01Å; T325-Y329 WeakPolarHBondContact O-CD2 3.48Å; T325-Y329 PolarHBondContact O-N 3.01Å
326N95.7Very high95.6Very high9 Ų920.5 Ų20.55%0.04810%0.101CC..Hα-helixtrans-59.3-49178.7-85.7-90.5000111.3S322 I323 I324 L328 Y329 H330 V331S322-N326 WeakPolarHBondContact O-CB 3.31Å; S322-N326 PolarHBondContact O-N 3.27Å; S322-N326 PolarHBondContact O-ND2 2.88Å; S322-N326 PolarHBondContact OG-ND2 3.26Å; I323-N326 PolarHBondContact O-N 3.46Å; I324-N326 PolarHBondContact O-N 2.82Å; N326-L328 PolarHBondContact O-N 2.98Å; N326-Y329 CarbonylContact O-C 3.57Å; N326-Y329 VanDerWaalsContact O-C 3.26Å; N326-Y329 PolarHBondContact O-N 2.77Å; N326-H330 PolarHBondContact O-N 2.7Å; N326-V331 HydrophobicContact CB-CB 3.82Å; N326-V331 HydrophobicContact CB-CG1 4.11Å; N326-V331 HydrophobicContact CB-CG2 4.02Å; N326-V331 VanDerWaalsContact O-CB 3.28Å; N326-V331 WeakPolarHBondContact O-CB 3.03Å; N326-V331 WeakPolarHBondContact O-CG2 2.93Å; N326-V331 PolarHBondContact O-N 3.33Å; N326-V331 WeakPolarHBondContact OD1-CG2 3.4Å
327L95.5Very high95.2Very high10 Ų1020.8 Ų20.85%0.05210%0.102CC..Hα-helixtrans-61.1-42.4177.5-69.4172000112V18 I323 I324 Y329 H330 F379 R389 V403V18-L327 HydrophobicContact CG1-CD2 3.64Å; I323-L327 HydrophobicContact CG2-CD1 3.95Å; I323-L327 HydrophobicContact CG2-CG 4.4Å; I323-L327 WeakPolarHBondContact O-CB 3.47Å; I323-L327 VanDerWaalsContact O-CG 3.31Å; I323-L327 WeakPolarHBondContact O-CG 3.48Å; I323-L327 PolarHBondContact O-N 3.27Å; I324-L327 PolarHBondContact O-N 3.43Å; L327-Y329 PolarHBondContact O-N 2.9Å; L327-H330 PolarHBondContact O-N 3.18Å; L327-F379 HydrophobicContact CD1-CD1 4.22Å; L327-F379 HydrophobicContact CD1-CE1 4.47Å; L327-R389 WeakPolarHBondContact O-CD 3.43Å; L327-V403 HydrophobicContact CB-CG2 4.05Å; L327-V403 HydrophobicContact CD1-CG1 4.09Å; L327-V403 HydrophobicContact CD1-CG2 4.35Å
328L96.2Very high94.7Very high70 Ų7020.3 Ų20.337%0.36610%0.099SC..Hα-helixtrans-64.7-23.2176.5-70.6176.1000113I324 T325 N326 V403I324-L328 HydrophobicContact CG2-CD1 3.73Å; I324-L328 HydrophobicContact CG2-CG 4.21Å; I324-L328 WeakPolarHBondContact O-CB 3.46Å; I324-L328 WeakPolarHBondContact O-CG 3.44Å; I324-L328 PolarHBondContact O-N 3.47Å; T325-L328 PolarHBondContact O-N 3.38Å; N326-L328 PolarHBondContact O-N 2.98Å; L328-V403 HydrophobicContact CD2-CG2 4.3Å
329Y96.4Very high94.2Very high65 Ų6517.3 Ų17.326%0.2559%0.086SC..THydrogen-bonded Turntrans-110.137.9177.6-67.7-64.4000113.6A276 K277 R281 T325 N326 L327 V331A276-Y329 HydrophobicContact CB-CD2 3.41Å; A276-Y329 VanDerWaalsContact CB-CD2 3.41Å; A276-Y329 HydrophobicContact CB-CE2 3.65Å; A276-Y329 HydrophobicContact CB-CG 4.13Å; K277-Y329 HydrophobicContact CB-CE1 4.11Å; K277-Y329 HydrophobicContact CG-CE1 4.44Å; R281-Y329 HydrophobicContact CB-CD1 3.75Å; R281-Y329 HydrophobicContact CB-CE1 4.15Å; R281-Y329 HydrophobicContact CG-CD1 4.24Å; T325-Y329 HydrophobicContact CG2-CD2 3.8Å; T325-Y329 HydrophobicContact CG2-CE2 4.01Å; T325-Y329 WeakPolarHBondContact O-CD2 3.48Å; T325-Y329 PolarHBondContact O-N 3.01Å; N326-Y329 CarbonylContact O-C 3.57Å; N326-Y329 VanDerWaalsContact O-C 3.26Å; N326-Y329 PolarHBondContact O-N 2.77Å; L327-Y329 PolarHBondContact O-N 2.9Å; Y329-V331 VanDerWaalsContact C-N 3.27Å; Y329-V331 PolarHBondContact O-N 3.47Å
330H95.9Very high93.6Very high63 Ų6317.3 Ų17.329%0.2929%0.086SC..THydrogen-bonded Turntrans70.711.3165.9-43.2-84.6000116.3H284 N326 L327H284-H330 HydrophobicContact CB-CB 4.12Å; H284-H330 AromaticContact CD2-CD2 3.34Å; H284-H330 PolarHBondContact CD2-CD2 3.47Å; H284-H330 AromaticContact CD2-CE1 3.5Å; H284-H330 AromaticContact CD2-CG 3.28Å; H284-H330 AromaticContact CD2-ND1 3.39Å; H284-H330 PolarHBondContact CD2-ND1 3.26Å; H284-H330 AromaticContact CD2-NE2 3.5Å; H284-H330 AromaticContact CG-CD2 3.6Å; H284-H330 AromaticContact CG-CG 3.5Å; H284-H330 VanDerWaalsContact CG-CG 3.5Å; H284-H330 AromaticContact ND1-CG 3.97Å; H284-H330 AromaticContact NE2-CE1 3.75Å; H284-H330 AromaticContact NE2-CG 3.65Å; H284-H330 AromaticContact NE2-ND1 3.38Å; H284-H330 PolarHBondContact NE2-ND1 3.25Å; N326-H330 PolarHBondContact O-N 2.7Å; L327-H330 PolarHBondContact O-N 3.18Å
331V95.6Very high93.1Very high5 Ų517.3 Ų17.33%0.039%0.086CC..EExtended strand (participates in β ladder)trans-73.1131.4173.7178.60000109.5L280 L292 A294 N326 Y329 G333L280-V331 HydrophobicContact CD1-CG2 3.83Å; L280-V331 HydrophobicContact CD2-CG2 4.25Å; L292-V331 HydrophobicContact CB-CG2 3.96Å; L292-V331 CarbonylContact O-C 3.47Å; L292-V331 VanDerWaalsContact O-CA 3.31Å; L292-V331 WeakPolarHBondContact O-CA 3.21Å; A294-V331 HydrophobicContact CB-CG1 4.05Å; N326-V331 HydrophobicContact CB-CB 3.82Å; N326-V331 HydrophobicContact CB-CG1 4.11Å; N326-V331 HydrophobicContact CB-CG2 4.02Å; N326-V331 VanDerWaalsContact O-CB 3.28Å; N326-V331 WeakPolarHBondContact O-CB 3.03Å; N326-V331 WeakPolarHBondContact O-CG2 2.93Å; N326-V331 PolarHBondContact O-N 3.33Å; N326-V331 WeakPolarHBondContact OD1-CG2 3.4Å; Y329-V331 VanDerWaalsContact C-N 3.27Å; Y329-V331 PolarHBondContact O-N 3.47Å; V331-G333 WeakPolarHBondContact CG1-O 3.39Å
332V94.1Very high92.6Very high16 Ų1616.1 Ų16.110%0.0978%0.081CC..EExtended strand (participates in β ladder)trans-93.5-10.5-171.4-53.90000113.6V18 S19 M291 L292 F293V18-V332 CarbonylContact C-O 3.38Å; V18-V332 WeakPolarHBondContact CA-O 3.46Å; V18-V332 WeakPolarHBondContact CG1-O 3.08Å; S19-V332 CarbonylContact C-O 3.58Å; S19-V332 PolarHBondContact N-O 3.5Å; M291-V332 HydrophobicContact CB-CG1 4.18Å; M291-V332 HydrophobicContact CB-CG2 4.14Å; M291-V332 HydrophobicContact CE-CG2 4.38Å; M291-V332 HydrophobicContact CG-CG2 4.37Å; M291-V332 HydrophobicContact SD-CG2 3.73Å; L292-V332 WeakPolarHBondContact O-CG2 3.49Å; L292-V332 PolarHBondContact O-N 2.98Å; F293-V332 HydrophobicContact CD2-CG2 4.24Å
333G90.6Very high92.4Very high3 Ų318.9 Ų18.93%0.03110%0.099CC..EExtended strand (participates in β ladder)trans-168.1163.5176.700000112.1S19 A294 V331S19-G333 WeakPolarHBondContact O-CA 3.48Å; A294-G333 PolarHBondContact N-O 2.94Å; V331-G333 WeakPolarHBondContact CG1-O 3.39Å
334W95.5Very high92.1Very high6 Ų624.3 Ų24.32%0.02312%0.124CC..EExtended strand (participates in β ladder)trans-143.9126.7-172.3-169.7103.6000110.9M21 A22 A294 A297 Y319 S322 I323 D336 L376M21-W334 WeakPolarHBondContact CA-O 3.21Å; M21-W334 WeakPolarHBondContact CB-O 3.44Å; M21-W334 HydrophobicContact CG-CB 3.91Å; M21-W334 HydrophobicContact CG-CE3 4.48Å; M21-W334 WeakPolarHBondContact CG-O 3.44Å; M21-W334 HydrophobicContact SD-CB 3.85Å; M21-W334 HydrophobicContact SD-CD2 3.96Å; M21-W334 HydrophobicContact SD-CE3 3.5Å; M21-W334 VanDerWaalsContact SD-CE3 3.5Å; M21-W334 HydrophobicContact SD-CG 4.15Å; M21-W334 HydrophobicContact SD-CZ3 4.38Å; A22-W334 PolarHBondContact N-O 3.5Å; A294-W334 HydrophobicContact CB-CB 4.23Å; A294-W334 HydrophobicContact CB-CG 4.02Å; A294-W334 CarbonylContact O-C 3.46Å; A294-W334 VanDerWaalsContact O-CA 3.27Å; A294-W334 WeakPolarHBondContact O-CA 3.19Å; A297-W334 HydrophobicContact CB-CH2 3.44Å; A297-W334 VanDerWaalsContact CB-CH2 3.44Å; A297-W334 HydrophobicContact CB-CZ2 3.13Å; A297-W334 HydrophobicContact CB-CZ3 4.38Å; Y319-W334 AromaticContact CD1-CH2 3.47Å; Y319-W334 HydrophobicContact CD1-CH2 3.47Å; Y319-W334 VanDerWaalsContact CD1-CH2 3.47Å; Y319-W334 HydrophobicContact CD1-CZ2 4.33Å; Y319-W334 AromaticContact CD1-CZ3 3.99Å; Y319-W334 HydrophobicContact CD1-CZ3 3.99Å; Y319-W334 AromaticContact CE1-CH2 3.48Å; Y319-W334 HydrophobicContact CE1-CH2 3.48Å; Y319-W334 VanDerWaalsContact CE1-CH2 3.48Å; Y319-W334 AromaticContact CE1-CZ3 3.99Å; Y319-W334 HydrophobicContact CE1-CZ3 3.99Å; Y319-W334 HydrophobicContact CG-CH2 4.24Å; S322-W334 PolarHBondContact OG-NE1 2.87Å; I323-W334 HydrophobicContact CG1-CD2 3.81Å; I323-W334 HydrophobicContact CG1-CE3 4.3Å; I323-W334 HydrophobicContact CG1-CG 3.91Å; W334-D336 HydrophobicContact CZ3-CB 3.84Å; W334-D336 VanDerWaalsContact CZ3-N 3.35Å; W334-L376 HydrophobicContact CE3-CD2 3.91Å; W334-L376 HydrophobicContact CH2-CD2 4.44Å; W334-L376 HydrophobicContact CZ3-CD2 3.6Å
335T90.8Very high91.8Very high0 Ų024.2 Ų24.20%012%0.124CC..EExtended strand (participates in β ladder)trans-120.9123.3-171.5-54.70000109.6A22 W76 F293 A294 S295 E296 A297A22-T335 HydrophobicContact CB-CG2 3.33Å; W76-T335 HydrophobicContact CB-CG2 3.97Å; F293-T335 WeakPolarHBondContact CE1-OG1 3.33Å; F293-T335 VanDerWaalsContact CZ-OG1 3.25Å; F293-T335 WeakPolarHBondContact CZ-OG1 3.22Å; A294-T335 WeakPolarHBondContact O-CB 3.42Å; A294-T335 PolarHBondContact O-N 3.08Å; A294-T335 PolarHBondContact O-OG1 2.89Å; S295-T335 VanDerWaalsContact O-CB 3.23Å; S295-T335 WeakPolarHBondContact O-CB 3.26Å; S295-T335 WeakPolarHBondContact O-CG2 3.48Å; E296-T335 CarbonylContact C-O 3.45Å; E296-T335 WeakPolarHBondContact CA-O 3.41Å; A297-T335 PolarHBondContact N-O 3.32Å; A297-T335 VanDerWaalsContact N-O 3.08Å
336D90.5Very high91.3Very high1 Ų122.9 Ų22.91%0.00512%0.115CC..EExtended strand (participates in β ladder)trans-67.1156.9168.2-175.445.3000110.2A22 S24 A297 Y319 W334 P357 L376A22-D336 WeakPolarHBondContact O-CB 3.22Å; A22-D336 PolarHBondContact O-N 3.14Å; S24-D336 PolarHBondContact N-O 3.2Å; A297-D336 VanDerWaalsContact O-OD1 3.08Å; Y319-D336 HydrophobicContact CE1-CB 4.45Å; Y319-D336 WeakPolarHBondContact CE1-OD1 3.25Å; Y319-D336 PolarHBondContact OH-OD1 2.84Å; W334-D336 HydrophobicContact CZ3-CB 3.84Å; W334-D336 VanDerWaalsContact CZ3-N 3.35Å; D336-P357 WeakPolarHBondContact OD2-CD 3.39Å; D336-P357 WeakPolarHBondContact OD2-CG 3.45Å; D336-L376 HydrophobicContact CB-CD1 4.42Å
337W88.4Confident90.9Very high6 Ų623.4 Ų23.42%0.02312%0.119CC..EExtended strand (participates in β ladder)trans-75.5-116.1173.5-160.8-140.2000111S24 W76 F84 W135 E296 A297 C298 L339S24-W337 VanDerWaalsContact CA-O 3.28Å; S24-W337 WeakPolarHBondContact CA-O 3.05Å; S24-W337 WeakPolarHBondContact CB-O 3.36Å; S24-W337 PolarHBondContact N-O 3.28Å; W76-W337 HydrophobicContact CD2-CZ3 4.26Å; W76-W337 HydrophobicContact CE3-CE3 4.31Å; W76-W337 AromaticContact CE3-CZ3 3.85Å; W76-W337 HydrophobicContact CE3-CZ3 3.85Å; W76-W337 HydrophobicContact CH2-CE3 4.13Å; W76-W337 AromaticContact CH2-CH2 3.07Å; W76-W337 HydrophobicContact CH2-CH2 3.07Å; W76-W337 HydrophobicContact CH2-CZ2 4.19Å; W76-W337 AromaticContact CH2-CZ3 2.99Å; W76-W337 HydrophobicContact CH2-CZ3 2.99Å; W76-W337 AromaticContact CZ2-CH2 3.91Å; W76-W337 HydrophobicContact CZ2-CH2 3.91Å; W76-W337 AromaticContact CZ2-CZ3 3.6Å; W76-W337 HydrophobicContact CZ2-CZ3 3.6Å; W76-W337 AromaticContact CZ3-CE3 3.88Å; W76-W337 HydrophobicContact CZ3-CE3 3.88Å; W76-W337 AromaticContact CZ3-CH2 3.46Å; W76-W337 HydrophobicContact CZ3-CH2 3.46Å; W76-W337 VanDerWaalsContact CZ3-CH2 3.46Å; W76-W337 HydrophobicContact CZ3-CZ2 4.32Å; W76-W337 AromaticContact CZ3-CZ3 3.15Å; W76-W337 HydrophobicContact CZ3-CZ3 3.15Å; F84-W337 AromaticContact CD2-NE1 3.5Å; F84-W337 AromaticContact CE2-CD1 3.97Å; F84-W337 AromaticContact CE2-NE1 3.5Å; W135-W337 HydrophobicContact CH2-CH2 4.37Å; W135-W337 AromaticContact CZ2-CH2 3.47Å; W135-W337 HydrophobicContact CZ2-CH2 3.47Å; W135-W337 VanDerWaalsContact CZ2-CH2 3.47Å; W135-W337 AromaticContact CZ2-CZ2 3.74Å; W135-W337 HydrophobicContact CZ2-CZ2 3.74Å; W135-W337 HydrophobicContact CZ2-CZ3 4.46Å; E296-W337 HydrophobicContact CB-CE3 3.92Å; E296-W337 HydrophobicContact CB-CZ3 3.93Å; E296-W337 VanDerWaalsContact CD-CD2 3.49Å; E296-W337 HydrophobicContact CG-CB 4.31Å; E296-W337 HydrophobicContact CG-CD2 3.7Å; E296-W337 HydrophobicContact CG-CE3 3.26Å; E296-W337 HydrophobicContact CG-CG 4.19Å; E296-W337 HydrophobicContact CG-CH2 4.21Å; E296-W337 HydrophobicContact CG-CZ3 3.53Å; E296-W337 WeakPolarHBondContact OE1-CZ2 3.37Å; E296-W337 WeakPolarHBondContact OE2-CH2 3.39Å; E296-W337 WeakPolarHBondContact OE2-CZ3 3.46Å; A297-W337 PolarHBondContact O-N 3.36Å; C298-W337 HydrophobicContact CB-CB 3.73Å; C298-W337 HydrophobicContact CB-CG 4.45Å; W337-L339 PolarHBondContact O-N 2.94Å
338N87.3Confident90.7Very high1 Ų123.4 Ų23.41%0.00512%0.119CC..EExtended strand (participates in β ladder)trans-68.6123.2-175.4-63.5-68.7000113.1T26 G27 F84 A340 L341 S356T26-N338 WeakPolarHBondContact CB-OD1 3.36Å; G27-N338 PolarHBondContact N-OD1 3.24Å; F84-N338 WeakPolarHBondContact CD1-ND2 3.27Å; F84-N338 WeakPolarHBondContact CD2-ND2 3.46Å; F84-N338 VanDerWaalsContact CE1-ND2 3.29Å; F84-N338 WeakPolarHBondContact CE1-ND2 3.29Å; F84-N338 WeakPolarHBondContact CE2-ND2 3.48Å; F84-N338 WeakPolarHBondContact CG-ND2 3.37Å; F84-N338 VanDerWaalsContact CZ-ND2 3.35Å; F84-N338 WeakPolarHBondContact CZ-ND2 3.39Å; N338-A340 VanDerWaalsContact C-N 3.28Å; N338-A340 PolarHBondContact O-N 3.37Å; N338-L341 HydrophobicContact CB-CD1 3.97Å; N338-L341 HydrophobicContact CB-CD2 3.78Å; N338-L341 HydrophobicContact CB-CG 3.72Å; N338-S356 WeakPolarHBondContact O-CB 3.45Å; N338-S356 PolarHBondContact O-OG 3.48Å
339L85Confident90.4Very high12 Ų1224.5 Ų24.56%0.06312%0.119CC..SBendtrans-60.3-34.9178.5-171.367.5000113.3S24 L25 L28 N64 Y72 W337 S356S24-L339 WeakPolarHBondContact O-CB 3.31Å; S24-L339 PolarHBondContact O-N 3.35Å; L25-L339 HydrophobicContact CD2-CD2 3.74Å; L28-L339 HydrophobicContact CD1-CB 4.34Å; L28-L339 HydrophobicContact CD1-CD2 3.87Å; L28-L339 HydrophobicContact CD1-CG 4.1Å; N64-L339 HydrophobicContact CB-CD1 4.42Å; N64-L339 VanDerWaalsContact ND2-CD1 3.31Å; N64-L339 WeakPolarHBondContact ND2-CD1 3.44Å; Y72-L339 HydrophobicContact CD2-CD1 4.11Å; Y72-L339 HydrophobicContact CE2-CD1 3.7Å; W337-L339 PolarHBondContact O-N 2.94Å; L339-S356 PolarHBondContact O-OG 3.44Å
340A84.4Confident90.3Very high0 Ų023.3 Ų23.30%012%0.118CC..  trans-149.7151.2170.900000111.1G27 L28 L31 N338 S356 I358 V360G27-A340 CarbonylContact C-O 3.57Å; G27-A340 WeakPolarHBondContact CA-O 3.46Å; L28-A340 HydrophobicContact CD1-CB 3.5Å; L28-A340 VanDerWaalsContact CD1-CB 3.5Å; L31-A340 HydrophobicContact CD1-CB 4.21Å; N338-A340 VanDerWaalsContact C-N 3.28Å; N338-A340 PolarHBondContact O-N 3.37Å; A340-S356 VanDerWaalsContact CA-OG 3.24Å; A340-S356 WeakPolarHBondContact CA-OG 3.19Å; A340-S356 PolarHBondContact N-OG 3.28Å; A340-I358 CarbonylContact C-O 3.57Å; A340-I358 WeakPolarHBondContact CA-O 3.38Å; A340-I358 HydrophobicContact CB-CB 4.08Å; A340-I358 HydrophobicContact CB-CG2 4.06Å; A340-V360 HydrophobicContact CB-CG2 3.99Å
341L87.3Confident90.1Very high0 Ų029.9 Ų29.90%014%0.141CC..BIsolated β-bridgetrans-137.1168.1172.8-68.9172.5000110.8F84 N338 G346 V354 I358 I359 V360F84-L341 HydrophobicContact CD1-CD2 3.76Å; F84-L341 HydrophobicContact CE1-CD1 4.06Å; F84-L341 HydrophobicContact CE1-CD2 3.69Å; N338-L341 HydrophobicContact CB-CD1 3.97Å; N338-L341 HydrophobicContact CB-CD2 3.78Å; N338-L341 HydrophobicContact CB-CG 3.72Å; L341-G346 WeakPolarHBondContact CD2-O 3.17Å; L341-V354 HydrophobicContact CD1-CG2 3.74Å; L341-V354 WeakPolarHBondContact CD1-O 3.39Å; L341-I358 PolarHBondContact N-O 3.46Å; L341-I359 HydrophobicContact CB-CD1 4.33Å; L341-I359 CarbonylContact O-C 3.46Å; L341-I359 VanDerWaalsContact O-CA 3.27Å; L341-I359 WeakPolarHBondContact O-CA 3.46Å; L341-V360 PolarHBondContact O-N 3.08Å
342N87.9Confident89.9Confident32 Ų3232.3 Ų32.317%0.17115%0.153CC..  trans-76.8174.1170.376.66.5000111.5L31 E344 G345 G346L31-N342 HydrophobicContact CD2-CB 3.97Å; N342-E344 PolarHBondContact O-N 3.02Å; N342-E344 VanDerWaalsContact O-N 3.12Å; N342-E344 WeakPolarHBondContact OD1-CA 3.46Å; N342-E344 WeakPolarHBondContact OD1-CB 3.41Å; N342-E344 PolarHBondContact OD1-N 3.37Å; N342-G345 PolarHBondContact O-N 2.94Å; N342-G345 PolarHBondContact OD1-N 2.85Å; N342-G346 PolarHBondContact N-O 3.43Å; N342-G346 PolarHBondContact OD1-N 2.92Å; N342-G346 PolarHBondContact OD1-O 3.34Å
343P91.5Very high89.8Confident64 Ų6433.1 Ų33.142%0.41616%0.155SC..THydrogen-bonded Turntrans-65.2-12.9180-23.435.8000115.4V308 I359 V360 D361V308-P343 WeakPolarHBondContact CB-O 3.28Å; P343-I359 HydrophobicContact CB-CG2 4.2Å; P343-I359 HydrophobicContact CG-CG2 3.96Å; P343-V360 WeakPolarHBondContact CD-O 3.29Å; P343-D361 HydrophobicContact CG-CB 4.44Å
344E91.5Very high89.9Confident117 Ų11733 Ų3355%0.54716%0.155SC..THydrogen-bonded Turntrans-84.8-19.8173.1-167.3177.1-17000111.9N342 F353N342-E344 PolarHBondContact O-N 3.02Å; N342-E344 VanDerWaalsContact O-N 3.12Å; N342-E344 WeakPolarHBondContact OD1-CA 3.46Å; N342-E344 WeakPolarHBondContact OD1-CB 3.41Å; N342-E344 PolarHBondContact OD1-N 3.37Å; E344-F353 HydrophobicContact CG-CD2 4Å; E344-F353 HydrophobicContact CG-CE2 3.74Å; E344-F353 HydrophobicContact CG-CZ 4.17Å; E344-F353 WeakPolarHBondContact OE1-CE2 3.48Å
345G89.9Confident89.9Confident0 Ų032.8 Ų32.80%015%0.154CC..SBendtrans93.824.2-175.900000113.8V308 N342 F353 V354V308-G345 VanDerWaalsContact CG2-CA 3.41Å; N342-G345 PolarHBondContact O-N 2.94Å; N342-G345 PolarHBondContact OD1-N 2.85Å; G345-F353 WeakPolarHBondContact O-CA 3.46Å; G345-F353 WeakPolarHBondContact O-CB 3.31Å; G345-F353 WeakPolarHBondContact O-CD1 3.31Å; G345-V354 WeakPolarHBondContact CA-O 3.4Å; G345-V354 PolarHBondContact O-N 3.3Å
346G86.5Confident90Very high0 Ų032.8 Ų32.80%015%0.154CC..  trans-135.4-153.7179.600000112.9L341 N342L341-G346 WeakPolarHBondContact CD2-O 3.17Å; N342-G346 PolarHBondContact N-O 3.43Å; N342-G346 PolarHBondContact OD1-N 2.92Å; N342-G346 PolarHBondContact OD1-O 3.34Å
347P89.2Confident90Very high20 Ų2032.9 Ų32.913%0.1315%0.154CC..  cis-74.7156.65.435-39.6000112.7L30 V34 I86L30-P347 HydrophobicContact CB-CG 3.39Å; L30-P347 HydrophobicContact CD1-CG 3.93Å; L30-P347 WeakPolarHBondContact CD1-O 3.41Å; L30-P347 HydrophobicContact CD2-CG 4.03Å; L30-P347 HydrophobicContact CG-CG 3.98Å; V34-P347 HydrophobicContact CG2-CB 4.24Å; V34-P347 HydrophobicContact CG2-CG 3.82Å; I86-P347 HydrophobicContact CG2-CB 4.07Å; I86-P347 HydrophobicContact CG2-CG 3.98Å
348N91.1Very high90.1Very high10 Ų1032.6 Ų32.65%0.05315%0.153CC..  trans-155122.7-178.4179.1-62.5000107.3D83 F84 V350 R351 N352 F353D83-N348 VanDerWaalsContact C-ND2 3.28Å; D83-N348 WeakPolarHBondContact O-CA 3.43Å; D83-N348 PolarHBondContact O-ND2 3.34Å; D83-N348 PolarHBondContact O-OD1 3.31Å; D83-N348 PolarHBondContact OD2-ND2 2.99Å; F84-N348 HydrophobicContact CD1-CB 4.2Å; F84-N348 WeakPolarHBondContact CD2-ND2 3.48Å; F84-N348 HydrophobicContact CE1-CB 4.17Å; F84-N348 WeakPolarHBondContact CE2-ND2 3.28Å; F84-N348 WeakPolarHBondContact CZ-ND2 3.33Å; N348-V350 PolarHBondContact O-N 2.89Å; N348-V350 WeakPolarHBondContact OD1-CG2 3.46Å; N348-V350 PolarHBondContact OD1-N 3.16Å; N348-V350 VanDerWaalsContact OD1-N 3.13Å; N348-R351 PolarHBondContact O-N 3.3Å; N348-R351 PolarHBondContact OD1-N 3.48Å; N348-R351 VanDerWaalsContact OD1-N 3.1Å; N348-N352 PolarHBondContact ND2-O 3.44Å; N348-N352 PolarHBondContact OD1-N 2.93Å; N348-F353 HydrophobicContact CB-CD1 3.8Å; N348-F353 HydrophobicContact CB-CE1 3.85Å
349W90.1Very high90.3Very high93 Ų9332.5 Ų32.535%0.35215%0.153SC..THydrogen-bonded Turntrans-66.9-22.4-169.272.8-85.1000113.8C82 D83 S85 T88 F202C82-W349 PolarHBondContact O-NE1 2.99Å; D83-W349 VanDerWaalsContact O-CD1 3.25Å; D83-W349 PolarHBondContact O-N 3.42Å; D83-W349 VanDerWaalsContact O-N 3.14Å; S85-W349 VanDerWaalsContact O-CB 3.25Å; S85-W349 WeakPolarHBondContact O-CB 3.39Å; S85-W349 VanDerWaalsContact O-CD1 3.27Å; S85-W349 PolarHBondContact O-N 3.39Å; S85-W349 VanDerWaalsContact O-N 3.14Å; T88-W349 HydrophobicContact CG2-CD2 4Å; T88-W349 HydrophobicContact CG2-CE3 4.4Å; T88-W349 HydrophobicContact CG2-CH2 4.08Å; T88-W349 HydrophobicContact CG2-CZ2 3.62Å; T88-W349 HydrophobicContact CG2-CZ3 4.44Å; F202-W349 HydrophobicContact CB-CZ2 3.97Å
350V93.4Very high90.4Very high41 Ų4132.5 Ų32.525%0.24815%0.153CC..THydrogen-bonded Turntrans-100.95.4174.5-69.60000113.5D83 F202 N348 N352D83-V350 HydrophobicContact CB-CG2 3.9Å; F202-V350 HydrophobicContact CB-CG1 4.09Å; F202-V350 HydrophobicContact CB-CG2 3.96Å; F202-V350 HydrophobicContact CD1-CG2 3.89Å; F202-V350 HydrophobicContact CG-CG2 4.3Å; N348-V350 PolarHBondContact O-N 2.89Å; N348-V350 WeakPolarHBondContact OD1-CG2 3.46Å; N348-V350 PolarHBondContact OD1-N 3.16Å; N348-V350 VanDerWaalsContact OD1-N 3.13Å; V350-N352 HydrophobicContact CG2-CB 3.85Å; V350-N352 PolarHBondContact O-N 3.16Å
351R92.3Very high90.5Very high201 Ų20133.3 Ų33.376%0.75816%0.157SC*.  trans5831.7-176.6-54.4-178.5172.3-173.9-4.8113.8N348 F353N348-R351 PolarHBondContact O-N 3.3Å; N348-R351 PolarHBondContact OD1-N 3.48Å; N348-R351 VanDerWaalsContact OD1-N 3.1Å; R351-F353 HydrophobicContact CB-CD2 4.39Å; R351-F353 HydrophobicContact CB-CE1 4.43Å; R351-F353 HydrophobicContact CB-CE2 3.89Å; R351-F353 HydrophobicContact CB-CZ 3.91Å; R351-F353 HydrophobicContact CG-CE2 4.18Å; R351-F353 HydrophobicContact CG-CZ 3.9Å; R351-F353 PolarHBondContact O-N 3.02Å
352N90.6Very high90.3Very high55 Ų5536.7 Ų36.729%0.29418%0.175SC..  trans-80.660.1171.4-174.343.6000110.3D83 F84 N348 V350D83-N352 PolarHBondContact OD2-ND2 2.83Å; F84-N352 VanDerWaalsContact CZ-O 3.31Å; F84-N352 WeakPolarHBondContact CZ-O 3.46Å; N348-N352 PolarHBondContact ND2-O 3.44Å; N348-N352 PolarHBondContact OD1-N 2.93Å; V350-N352 HydrophobicContact CG2-CB 3.85Å; V350-N352 PolarHBondContact O-N 3.16Å
353F93.1Very high90.2Very high33 Ų3341.2 Ų41.215%0.14520%0.204CC..  trans-72.9144-171.6-58.4-43.6000112.8S307 E344 G345 N348 R351S307-F353 WeakPolarHBondContact CB-O 3.31Å; S307-F353 VanDerWaalsContact OG-CB 3.27Å; S307-F353 WeakPolarHBondContact OG-CB 3.36Å; S307-F353 PolarHBondContact OG-O 2.88Å; E344-F353 HydrophobicContact CG-CD2 4Å; E344-F353 HydrophobicContact CG-CE2 3.74Å; E344-F353 HydrophobicContact CG-CZ 4.17Å; E344-F353 WeakPolarHBondContact OE1-CE2 3.48Å; G345-F353 WeakPolarHBondContact O-CA 3.46Å; G345-F353 WeakPolarHBondContact O-CB 3.31Å; G345-F353 WeakPolarHBondContact O-CD1 3.31Å; N348-F353 HydrophobicContact CB-CD1 3.8Å; N348-F353 HydrophobicContact CB-CE1 3.85Å; R351-F353 HydrophobicContact CB-CD2 4.39Å; R351-F353 HydrophobicContact CB-CE1 4.43Å; R351-F353 HydrophobicContact CB-CE2 3.89Å; R351-F353 HydrophobicContact CB-CZ 3.91Å; R351-F353 HydrophobicContact CG-CE2 4.18Å; R351-F353 HydrophobicContact CG-CZ 3.9Å; R351-F353 PolarHBondContact O-N 3.02Å
354V92.4Very high89.9Confident2 Ų244.2 Ų44.21%0.01221%0.21CC..  trans-138.3175.7-178.8-55.60000111F84 C298 S307 L341 G345F84-V354 HydrophobicContact CE1-CG2 4.13Å; F84-V354 HydrophobicContact CE2-CG2 4.16Å; F84-V354 HydrophobicContact CZ-CB 4.33Å; F84-V354 HydrophobicContact CZ-CG1 4.19Å; F84-V354 HydrophobicContact CZ-CG2 3.43Å; F84-V354 VanDerWaalsContact CZ-CG2 3.43Å; C298-V354 HydrophobicContact CB-CG2 4.28Å; S307-V354 CarbonylContact O-C 3.46Å; L341-V354 HydrophobicContact CD1-CG2 3.74Å; L341-V354 WeakPolarHBondContact CD1-O 3.39Å; G345-V354 WeakPolarHBondContact CA-O 3.4Å; G345-V354 PolarHBondContact O-N 3.3Å
355D95.2Very high89.5Confident1 Ų141.7 Ų41.71%0.00520%0.2CC..  trans-85.5165.2171.1-145-26.1000111V299 S307 R309 R315 Q370 M372V299-D355 HydrophobicContact CG2-CB 3.74Å; V299-D355 PolarHBondContact O-N 3.09Å; S307-D355 WeakPolarHBondContact O-CA 3.04Å; S307-D355 WeakPolarHBondContact O-CB 3.37Å; S307-D355 PolarHBondContact O-N 3.43Å; S307-D355 VanDerWaalsContact O-N 3.11Å; R309-D355 PolarHBondContact N-OD2 2.57Å; R309-D355 VanDerWaalsContact N-OD2 3.15Å; R315-D355 VanDerWaalsContact CD-OD2 3.29Å; R315-D355 WeakPolarHBondContact CD-OD2 3.35Å; R315-D355 IonicContact CZ-OD2 3.44Å; R315-D355 IonicContact NE-OD2 3.23Å; R315-D355 VanDerWaalsContact NH1-CG 3.33Å; R315-D355 IonicContact NH1-OD2 3.77Å; R315-D355 PolarHBondContact NH1-OD2 3.41Å; D355-Q370 PolarHBondContact OD1-NE2 3.32Å; D355-M372 HydrophobicContact CB-CE 3.84Å; D355-M372 WeakPolarHBondContact OD1-CE 3.38Å
356S92.3Very high89.3Confident0 Ų044.3 Ų44.30%022%0.217CC..  trans-141.1150.5172.9170.50000110N338 L339 A340 I358 Q370 M372N338-S356 WeakPolarHBondContact O-CB 3.45Å; N338-S356 PolarHBondContact O-OG 3.48Å; L339-S356 PolarHBondContact O-OG 3.44Å; A340-S356 VanDerWaalsContact CA-OG 3.24Å; A340-S356 WeakPolarHBondContact CA-OG 3.19Å; A340-S356 PolarHBondContact N-OG 3.28Å; S356-I358 PolarHBondContact O-N 2.92Å; S356-I358 PolarHBondContact OG-N 2.89Å; S356-I358 PolarHBondContact OG-O 2.89Å; S356-Q370 WeakPolarHBondContact O-CG 3.49Å; S356-M372 VanDerWaalsContact O-CE 3.25Å; S356-M372 WeakPolarHBondContact O-CE 3.05Å
357P90.9Very high89.5Confident2 Ų246.4 Ų46.41%0.01323%0.226CC..SBendtrans-54.7-23.1172.6-28.637.9000114.6Y319 D336 Q370 M372 F373 L376Y319-P357 HydrophobicContact CE1-CG 4.29Å; D336-P357 WeakPolarHBondContact OD2-CD 3.39Å; D336-P357 WeakPolarHBondContact OD2-CG 3.45Å; P357-Q370 WeakPolarHBondContact O-CB 3.47Å; P357-Q370 PolarHBondContact O-N 2.98Å; P357-M372 HydrophobicContact CB-CB 4.27Å; P357-M372 HydrophobicContact CG-CB 4.19Å; P357-F373 HydrophobicContact CB-CB 3.97Å; P357-L376 HydrophobicContact CB-CD1 4.26Å; P357-L376 HydrophobicContact CG-CD1 3.6Å
358I90.5Very high89.5Confident0 Ų049 Ų490%023%0.234CC..EExtended strand (participates in β ladder)trans-128.5126.3177.6-61.8176.8000109.8T60 N64 A340 L341 S356 V360 F367 Y368 F373T60-I358 HydrophobicContact CG2-CD1 3.55Å; T60-I358 HydrophobicContact CG2-CG2 4.27Å; N64-I358 WeakPolarHBondContact ND2-CD1 3.49Å; A340-I358 CarbonylContact C-O 3.57Å; A340-I358 WeakPolarHBondContact CA-O 3.38Å; A340-I358 HydrophobicContact CB-CB 4.08Å; A340-I358 HydrophobicContact CB-CG2 4.06Å; L341-I358 PolarHBondContact N-O 3.46Å; S356-I358 PolarHBondContact O-N 2.92Å; S356-I358 PolarHBondContact OG-N 2.89Å; S356-I358 PolarHBondContact OG-O 2.89Å; I358-V360 HydrophobicContact CG2-CG2 4.2Å; I358-F367 HydrophobicContact CG2-CB 3.99Å; I358-F367 HydrophobicContact CG2-CD2 3.94Å; I358-F367 HydrophobicContact CG2-CG 4.34Å; I358-Y368 WeakPolarHBondContact CA-O 3.16Å; I358-F373 HydrophobicContact CD1-CD2 3.85Å; I358-F373 HydrophobicContact CD1-CE2 3.96Å; I358-F373 HydrophobicContact CG1-CD2 3.88Å; I358-F373 HydrophobicContact CG1-CE2 4.47Å
359I90.9Very high89.6Confident0 Ų052 Ų520%025%0.246CC..EExtended strand (participates in β ladder)trans-111121.9175.9-58.1-59.5000109.7V308 L310 L341 P343 F367 Y368 Q370V308-I359 HydrophobicContact CB-CD1 4.46Å; V308-I359 HydrophobicContact CG1-CD1 3.75Å; V308-I359 HydrophobicContact CG1-CG1 3.8Å; V308-I359 HydrophobicContact CG1-CG2 4.42Å; V308-I359 HydrophobicContact CG2-CD1 3.79Å; L310-I359 HydrophobicContact CD2-CB 3.9Å; L310-I359 HydrophobicContact CD2-CG1 3.89Å; L310-I359 HydrophobicContact CD2-CG2 4.05Å; L341-I359 HydrophobicContact CB-CD1 4.33Å; L341-I359 CarbonylContact O-C 3.46Å; L341-I359 VanDerWaalsContact O-CA 3.27Å; L341-I359 WeakPolarHBondContact O-CA 3.46Å; P343-I359 HydrophobicContact CB-CG2 4.2Å; P343-I359 HydrophobicContact CG-CG2 3.96Å; I359-F367 CarbonylContact O-C 3.36Å; I359-F367 VanDerWaalsContact O-CA 3.22Å; I359-F367 WeakPolarHBondContact O-CA 2.88Å; I359-Y368 HydrophobicContact CB-CD2 4.27Å; I359-Y368 HydrophobicContact CG2-CD2 4.25Å; I359-Y368 PolarHBondContact N-O 2.92Å; I359-Y368 WeakPolarHBondContact O-CD2 3.37Å; I359-Y368 PolarHBondContact O-N 3.12Å; I359-Q370 HydrophobicContact CG1-CG 4.05Å
360V86.6Confident89.8Confident12 Ų1247.9 Ų47.97%0.07323%0.231CC..EExtended strand (participates in β ladder)trans-103120.4-177-178.50000110.3L31 A340 L341 P343 I358 I362 F367L31-V360 HydrophobicContact CD1-CB 3.5Å; L31-V360 HydrophobicContact CD1-CG1 4.01Å; L31-V360 HydrophobicContact CD1-CG2 3.52Å; L31-V360 HydrophobicContact CD2-CB 4.07Å; L31-V360 HydrophobicContact CD2-CG1 4.34Å; L31-V360 HydrophobicContact CG-CB 4.43Å; A340-V360 HydrophobicContact CB-CG2 3.99Å; L341-V360 PolarHBondContact O-N 3.08Å; P343-V360 WeakPolarHBondContact CD-O 3.29Å; I358-V360 HydrophobicContact CG2-CG2 4.2Å; V360-I362 HydrophobicContact CG1-CG1 4.17Å; V360-F367 HydrophobicContact CG2-CB 4.01Å
361D87.4Confident90.1Very high16 Ų1646.6 Ų46.69%0.08622%0.223CC..EExtended strand (participates in β ladder)trans-100.693.3171.6-174.2-11.7000109.1P343 T363 K364 D365 T366 Y368P343-D361 HydrophobicContact CG-CB 4.44Å; D361-T363 PolarHBondContact O-N 3.08Å; D361-T363 PolarHBondContact OD1-N 2.97Å; D361-T363 PolarHBondContact OD1-OG1 3.34Å; D361-K364 PolarHBondContact O-N 3.24Å; D361-K364 VanDerWaalsContact O-N 3.16Å; D361-K364 WeakPolarHBondContact OD2-CD 3.31Å; D361-K364 WeakPolarHBondContact OD2-CE 3.37Å; D361-K364 IonicContact OD2-NZ 3.25Å; D361-K364 PolarHBondContact OD2-NZ 3.03Å; D361-D365 PolarHBondContact O-N 3.04Å; D361-T366 PolarHBondContact N-O 2.62Å; D361-T366 PolarHBondContact O-N 3.04Å; D361-Y368 HydrophobicContact CB-CE2 3.87Å
362I83.2Confident90.2Very high71 Ų7137.1 Ų37.136%0.36419%0.188SC..G310 helixtrans-60.1-33.3-178.4-59.5172.8000110.9L31 V360 K364 D365L31-I362 HydrophobicContact CB-CD1 4.21Å; L31-I362 HydrophobicContact CD2-CD1 3.68Å; L31-I362 HydrophobicContact CD2-CG1 4.05Å; V360-I362 HydrophobicContact CG1-CG1 4.17Å; I362-K364 PolarHBondContact O-N 3.26Å; I362-D365 PolarHBondContact O-N 3.5Å
363T84.8Confident90.4Very high127 Ų12734.6 Ų34.678%0.77917%0.174SC*.G310 helixtrans-66.7-21.6-177.972.20000113D361D361-T363 PolarHBondContact O-N 3.08Å; D361-T363 PolarHBondContact OD1-N 2.97Å; D361-T363 PolarHBondContact OD1-OG1 3.34Å
364K86Confident90.6Very high127 Ų12738.5 Ų38.555%0.55219%0.189SC*.G310 helixtrans-113.46.1179.8-58.7-171-169.7114.40113.6D361 I362 T366D361-K364 PolarHBondContact O-N 3.24Å; D361-K364 VanDerWaalsContact O-N 3.16Å; D361-K364 WeakPolarHBondContact OD2-CD 3.31Å; D361-K364 WeakPolarHBondContact OD2-CE 3.37Å; D361-K364 IonicContact OD2-NZ 3.25Å; D361-K364 PolarHBondContact OD2-NZ 3.03Å; I362-K364 PolarHBondContact O-N 3.26Å; K364-T366 PolarHBondContact O-N 2.84Å; K364-T366 VanDerWaalsContact O-N 3.11Å; K364-T366 PolarHBondContact O-OG1 2.99Å
365D83.3Confident90.8Very high64 Ų6438.4 Ų38.434%0.34219%0.188SC..THydrogen-bonded Turntrans44.642.7-170.6-174.328000112.7R59 D361 I362R59-D365 IonicContact NH2-OD1 3.45Å; R59-D365 PolarHBondContact NH2-OD1 3.28Å; R59-D365 IonicContact NH2-OD2 3.37Å; D361-D365 PolarHBondContact O-N 3.04Å; I362-D365 PolarHBondContact O-N 3.5Å
366T86.3Confident90.8Very high56 Ų5638.4 Ų38.434%0.34419%0.188SC..EExtended strand (participates in β ladder)trans-131.2148.6-172.1-63.90000110.2D361 K364 Y368D361-T366 PolarHBondContact N-O 2.62Å; D361-T366 PolarHBondContact O-N 3.04Å; K364-T366 PolarHBondContact O-N 2.84Å; K364-T366 VanDerWaalsContact O-N 3.11Å; K364-T366 PolarHBondContact O-OG1 2.99Å; T366-Y368 HydrophobicContact CG2-CD1 4.5Å; T366-Y368 HydrophobicContact CG2-CE1 4.03Å
367F89.2Confident90.8Very high43 Ų4338.6 Ų38.619%0.18919%0.19CC..EExtended strand (participates in β ladder)trans-125.8147.2168.567.7-84.7000110.8R59 I358 I359 V360 K369R59-F367 HydrophobicContact CB-CD1 4.45Å; R59-F367 HydrophobicContact CB-CE1 3.46Å; R59-F367 VanDerWaalsContact CB-CE1 3.46Å; R59-F367 HydrophobicContact CB-CZ 3.81Å; R59-F367 HydrophobicContact CG-CE1 4.34Å; I358-F367 HydrophobicContact CG2-CB 3.99Å; I358-F367 HydrophobicContact CG2-CD2 3.94Å; I358-F367 HydrophobicContact CG2-CG 4.34Å; I359-F367 CarbonylContact O-C 3.36Å; I359-F367 VanDerWaalsContact O-CA 3.22Å; I359-F367 WeakPolarHBondContact O-CA 2.88Å; V360-F367 HydrophobicContact CG2-CB 4.01Å; F367-K369 HydrophobicContact CD2-CG 4.03Å; F367-K369 HydrophobicContact CE2-CD 3.94Å; F367-K369 HydrophobicContact CE2-CG 3.75Å
368Y89.8Confident91.1Very high76 Ų7640.6 Ų40.630%0.29820%0.199SC..EExtended strand (participates in β ladder)trans-109.2119.9178.7-50.2-73.1000109L310 I358 I359 D361 T366 Q370L310-Y368 HydrophobicContact CD1-CD2 4.43Å; L310-Y368 HydrophobicContact CD2-CD2 4.03Å; L310-Y368 HydrophobicContact CD2-CG 4.26Å; I358-Y368 WeakPolarHBondContact CA-O 3.16Å; I359-Y368 HydrophobicContact CB-CD2 4.27Å; I359-Y368 HydrophobicContact CG2-CD2 4.25Å; I359-Y368 PolarHBondContact N-O 2.92Å; I359-Y368 WeakPolarHBondContact O-CD2 3.37Å; I359-Y368 PolarHBondContact O-N 3.12Å; D361-Y368 HydrophobicContact CB-CE2 3.87Å; T366-Y368 HydrophobicContact CG2-CD1 4.5Å; T366-Y368 HydrophobicContact CG2-CE1 4.03Å; Y368-Q370 PolarHBondContact O-N 2.86Å
369K93.8Very high91.4Very high73 Ų7340.6 Ų40.632%0.31720%0.199SC..EExtended strand (participates in β ladder)trans-82.8111.7171.4-65.7169.857.4176.80108.6F367 F373 Y374F367-K369 HydrophobicContact CD2-CG 4.03Å; F367-K369 HydrophobicContact CE2-CD 3.94Å; F367-K369 HydrophobicContact CE2-CG 3.75Å; K369-F373 HydrophobicContact CB-CB 4.45Å; K369-F373 HydrophobicContact CB-CD1 4.43Å; K369-F373 HydrophobicContact CB-CG 4.32Å; K369-F373 HydrophobicContact CD-CE1 4.44Å; K369-F373 VanDerWaalsContact CE-CZ 3.47Å; K369-F373 VanDerWaalsContact NZ-CE1 3.32Å; K369-Y374 HydrophobicContact CB-CE2 3.95Å; K369-Y374 WeakPolarHBondContact CE-OH 3.33Å
370Q94.6Very high91.3Very high5 Ų540.6 Ų40.62%0.02320%0.199CC..  trans-73.6162.1-178.1-65.3-83.555.400111.4R309 D355 S356 P357 I359 Y368 M372 F373 Y374R309-Q370 PolarHBondContact O-NE2 2.94Å; D355-Q370 PolarHBondContact OD1-NE2 3.32Å; S356-Q370 WeakPolarHBondContact O-CG 3.49Å; P357-Q370 WeakPolarHBondContact O-CB 3.47Å; P357-Q370 PolarHBondContact O-N 2.98Å; I359-Q370 HydrophobicContact CG1-CG 4.05Å; Y368-Q370 PolarHBondContact O-N 2.86Å; Q370-M372 HydrophobicContact CB-CB 4.49Å; Q370-M372 HydrophobicContact CB-CE 3.93Å; Q370-M372 HydrophobicContact CG-CE 4.11Å; Q370-M372 PolarHBondContact O-N 3.37Å; Q370-M372 VanDerWaalsContact O-N 3.13Å; Q370-F373 VanDerWaalsContact O-CB 3.28Å; Q370-F373 WeakPolarHBondContact O-CB 3.35Å; Q370-F373 PolarHBondContact O-N 2.62Å; Q370-Y374 VanDerWaalsContact O-CD2 3.3Å; Q370-Y374 WeakPolarHBondContact O-CD2 3.45Å
371P98.2Very high91.5Very high15 Ų1543.1 Ų43.110%0.09721%0.209CC..Hα-helixtrans-49.7-37169.1-30.738.5000113.3W313 F373 Y374 H375W313-P371 HydrophobicContact CE3-CB 4.03Å; W313-P371 HydrophobicContact CE3-CG 4.36Å; P371-F373 VanDerWaalsContact C-N 3.27Å; P371-F373 PolarHBondContact O-N 2.97Å; P371-Y374 PolarHBondContact O-N 3.47Å; P371-H375 PolarHBondContact O-CD2 2.71Å; P371-H375 PolarHBondContact O-N 2.97Å
372M96.1Very high91.8Very high1 Ų145.2 Ų45.21%0.00522%0.218CC..Hα-helixtrans-52.8-41174.9-63.5176.9-71.200113.2V299 R315 Y319 D355 S356 P357 Q370 Y374 H375 L376V299-M372 HydrophobicContact CG2-CE 4.38Å; V299-M372 HydrophobicContact CG2-SD 3.45Å; V299-M372 WeakPolarHBondContact CG2-SD 3.13Å; R315-M372 HydrophobicContact CB-CG 3.86Å; R315-M372 HydrophobicContact CB-SD 3.84Å; Y319-M372 HydrophobicContact CD1-CB 4.38Å; Y319-M372 HydrophobicContact CD2-CB 4.37Å; Y319-M372 HydrophobicContact CD2-CG 3.84Å; Y319-M372 HydrophobicContact CD2-SD 3.92Å; Y319-M372 HydrophobicContact CE1-CB 4.43Å; Y319-M372 HydrophobicContact CE2-CB 4.42Å; Y319-M372 HydrophobicContact CE2-CG 3.89Å; Y319-M372 HydrophobicContact CE2-SD 3.35Å; Y319-M372 WeakPolarHBondContact CE2-SD 3.25Å; Y319-M372 HydrophobicContact CG-CB 4.34Å; Y319-M372 HydrophobicContact CG-CG 4.26Å; D355-M372 HydrophobicContact CB-CE 3.84Å; D355-M372 WeakPolarHBondContact OD1-CE 3.38Å; S356-M372 VanDerWaalsContact O-CE 3.25Å; S356-M372 WeakPolarHBondContact O-CE 3.05Å; P357-M372 HydrophobicContact CB-CB 4.27Å; P357-M372 HydrophobicContact CG-CB 4.19Å; Q370-M372 HydrophobicContact CB-CB 4.49Å; Q370-M372 HydrophobicContact CB-CE 3.93Å; Q370-M372 HydrophobicContact CG-CE 4.11Å; Q370-M372 PolarHBondContact O-N 3.37Å; Q370-M372 VanDerWaalsContact O-N 3.13Å; M372-Y374 VanDerWaalsContact C-N 3.33Å; M372-Y374 PolarHBondContact O-N 3.36Å; M372-H375 PolarHBondContact O-N 3.07Å; M372-L376 WeakPolarHBondContact O-CB 3.25Å; M372-L376 WeakPolarHBondContact O-CD1 3.4Å; M372-L376 WeakPolarHBondContact O-CG 3.38Å; M372-L376 PolarHBondContact O-N 3.43Å
373F94Very high92.4Very high3 Ų341.9 Ų41.91%0.01320%0.201CC..Hα-helixtrans-58.4-45.5176.9175.7-79.6000111.5A63 N64 I70 P357 I358 K369 Q370 P371 G377A63-F373 HydrophobicContact CB-CE2 4.13Å; A63-F373 HydrophobicContact CB-CZ 4.04Å; A63-F373 WeakPolarHBondContact O-CZ 3.17Å; N64-F373 WeakPolarHBondContact OD1-CE2 3.19Å; I70-F373 HydrophobicContact CB-CZ 4.32Å; I70-F373 HydrophobicContact CD1-CD1 4.43Å; I70-F373 HydrophobicContact CD1-CD2 3.89Å; I70-F373 HydrophobicContact CD1-CE1 4.1Å; I70-F373 HydrophobicContact CD1-CE2 3.59Å; I70-F373 HydrophobicContact CD1-CG 4.31Å; I70-F373 HydrophobicContact CD1-CZ 3.68Å; I70-F373 HydrophobicContact CG1-CE1 4.4Å; I70-F373 HydrophobicContact CG1-CE2 4.06Å; I70-F373 HydrophobicContact CG1-CZ 3.8Å; I70-F373 HydrophobicContact CG2-CD1 4.33Å; I70-F373 HydrophobicContact CG2-CE1 3.45Å; I70-F373 VanDerWaalsContact CG2-CE1 3.45Å; I70-F373 HydrophobicContact CG2-CZ 3.63Å; P357-F373 HydrophobicContact CB-CB 3.97Å; I358-F373 HydrophobicContact CD1-CD2 3.85Å; I358-F373 HydrophobicContact CD1-CE2 3.96Å; I358-F373 HydrophobicContact CG1-CD2 3.88Å; I358-F373 HydrophobicContact CG1-CE2 4.47Å; K369-F373 HydrophobicContact CB-CB 4.45Å; K369-F373 HydrophobicContact CB-CD1 4.43Å; K369-F373 HydrophobicContact CB-CG 4.32Å; K369-F373 HydrophobicContact CD-CE1 4.44Å; K369-F373 VanDerWaalsContact CE-CZ 3.47Å; K369-F373 VanDerWaalsContact NZ-CE1 3.32Å; Q370-F373 VanDerWaalsContact O-CB 3.28Å; Q370-F373 WeakPolarHBondContact O-CB 3.35Å; Q370-F373 PolarHBondContact O-N 2.62Å; P371-F373 VanDerWaalsContact C-N 3.27Å; P371-F373 PolarHBondContact O-N 2.97Å; F373-G377 PolarHBondContact O-N 2.58Å
374Y96.6Very high92.6Very high115 Ų11537.4 Ų37.445%0.45117%0.174SC..Hα-helixtrans-72.6-42.2-178.4-59.9-81.1000111.2K369 Q370 P371 M372 L376 G377 H378K369-Y374 HydrophobicContact CB-CE2 3.95Å; K369-Y374 WeakPolarHBondContact CE-OH 3.33Å; Q370-Y374 VanDerWaalsContact O-CD2 3.3Å; Q370-Y374 WeakPolarHBondContact O-CD2 3.45Å; P371-Y374 PolarHBondContact O-N 3.47Å; M372-Y374 VanDerWaalsContact C-N 3.33Å; M372-Y374 PolarHBondContact O-N 3.36Å; Y374-L376 VanDerWaalsContact C-N 3.3Å; Y374-L376 PolarHBondContact O-N 3.11Å; Y374-G377 CarbonylContact O-C 3.51Å; Y374-G377 WeakPolarHBondContact O-CA 3.16Å; Y374-G377 PolarHBondContact O-N 2.96Å; Y374-H378 PolarHBondContact O-CD2 2.99Å; Y374-H378 VanDerWaalsContact O-CD2 3.24Å; Y374-H378 PolarHBondContact O-N 3.26Å
375H98Very high92.8Very high0 Ų035.3 Ų35.30%017%0.166CC..Hα-helixtrans-59.8-39.1174.7-82-103.6000112W313 G316 S320 P371 M372 F379W313-H375 AromaticContact CE2-NE2 3.69Å; W313-H375 AromaticContact CH2-NE2 3.62Å; W313-H375 AromaticContact CZ2-NE2 3.49Å; W313-H375 WeakPolarHBondContact CZ2-NE2 3.4Å; W313-H375 AromaticContact CZ3-NE2 3.93Å; G316-H375 VanDerWaalsContact C-ND1 3.29Å; G316-H375 VanDerWaalsContact CA-CD2 3.48Å; G316-H375 WeakPolarHBondContact CA-CD2 3.47Å; G316-H375 WeakPolarHBondContact O-CB 3.15Å; G316-H375 PolarHBondContact O-ND1 2.81Å; G316-H375 VanDerWaalsContact O-ND1 3.08Å; S320-H375 WeakPolarHBondContact CB-ND1 3.44Å; S320-H375 PolarHBondContact OG-ND1 3.31Å; P371-H375 PolarHBondContact O-CD2 2.71Å; P371-H375 PolarHBondContact O-N 2.97Å; M372-H375 PolarHBondContact O-N 3.07Å; H375-F379 WeakPolarHBondContact O-CD2 3.33Å; H375-F379 VanDerWaalsContact O-CE2 3.3Å; H375-F379 WeakPolarHBondContact O-CE2 3.4Å
376L93.8Very high93Very high0 Ų033.5 Ų33.50%016%0.162CC..Hα-helixtrans-63.9-40.7169.4-80.6159.9000112.3M21 Y72 Y319 I323 W334 D336 P357 M372 Y374 H378 F379 S380M21-L376 HydrophobicContact CE-CD2 3.75Å; M21-L376 WeakPolarHBondContact CE-O 3.47Å; M21-L376 HydrophobicContact SD-CD2 3.36Å; M21-L376 WeakPolarHBondContact SD-CD2 3.19Å; Y72-L376 WeakPolarHBondContact OH-CD1 3.44Å; Y319-L376 HydrophobicContact CD1-CD1 3.53Å; Y319-L376 HydrophobicContact CD1-CD2 4Å; Y319-L376 HydrophobicContact CD1-CG 3.67Å; Y319-L376 HydrophobicContact CE1-CD1 3.62Å; Y319-L376 HydrophobicContact CE1-CG 4.27Å; I323-L376 HydrophobicContact CD1-CD2 3.89Å; W334-L376 HydrophobicContact CE3-CD2 3.91Å; W334-L376 HydrophobicContact CH2-CD2 4.44Å; W334-L376 HydrophobicContact CZ3-CD2 3.6Å; D336-L376 HydrophobicContact CB-CD1 4.42Å; P357-L376 HydrophobicContact CB-CD1 4.26Å; P357-L376 HydrophobicContact CG-CD1 3.6Å; M372-L376 WeakPolarHBondContact O-CB 3.25Å; M372-L376 WeakPolarHBondContact O-CD1 3.4Å; M372-L376 WeakPolarHBondContact O-CG 3.38Å; M372-L376 PolarHBondContact O-N 3.43Å; Y374-L376 VanDerWaalsContact C-N 3.3Å; Y374-L376 PolarHBondContact O-N 3.11Å; L376-H378 VanDerWaalsContact C-N 3.29Å; L376-H378 PolarHBondContact O-N 3.18Å; L376-F379 PolarHBondContact O-N 2.99Å; L376-S380 PolarHBondContact O-N 3.48Å; L376-S380 PolarHBondContact O-OG 3.09Å
377G92.6Very high93.4Very high5 Ų530.8 Ų30.85%0.05215%0.146CC..Hα-helixtrans-59.1-33.9177.900000114.4F373 Y374 F379 S380 K381F373-G377 PolarHBondContact O-N 2.58Å; Y374-G377 CarbonylContact O-C 3.51Å; Y374-G377 WeakPolarHBondContact O-CA 3.16Å; Y374-G377 PolarHBondContact O-N 2.96Å; G377-F379 PolarHBondContact O-N 3.43Å; G377-S380 WeakPolarHBondContact CA-OG 3.5Å; G377-K381 WeakPolarHBondContact O-CB 3.49Å; G377-K381 PolarHBondContact O-N 3.03Å
378H97.2Very high93.5Very high43 Ų4332.7 Ų32.720%0.19916%0.155CC..Hα-helixtrans-60.8-14.8176.9-88.4-84.3000114.4Y374 L376 V415 I445 T447Y374-H378 PolarHBondContact O-CD2 2.99Å; Y374-H378 VanDerWaalsContact O-CD2 3.24Å; Y374-H378 PolarHBondContact O-N 3.26Å; L376-H378 VanDerWaalsContact C-N 3.29Å; L376-H378 PolarHBondContact O-N 3.18Å; H378-V415 HydrophobicContact CB-CG1 4.48Å; H378-I445 HydrophobicContact CB-CD1 3.65Å; H378-I445 HydrophobicContact CB-CG1 4.05Å; H378-I445 PolarHBondContact CE1-O 3.11Å; H378-I445 PolarHBondContact NE2-O 3.39Å; H378-T447 WeakPolarHBondContact CB-OG1 3.49Å; H378-T447 PolarHBondContact ND1-OG1 3.21Å; H378-T447 PolarHBondContact O-OG1 2.59Å
379F96.3Very high93.8Very high0 Ų033.3 Ų33.30%016%0.157CC..Hα-helixtrans-116.4-55.7177.5-56.1-94000111.1I20 M21 I323 I324 L327 H375 L376 G377 K381 F382 I383 V403 V415 I445I20-F379 HydrophobicContact CG2-CB 4.03Å; M21-F379 HydrophobicContact CE-CB 3.23Å; M21-F379 HydrophobicContact CE-CD2 3.81Å; M21-F379 HydrophobicContact CE-CG 3.77Å; I323-F379 HydrophobicContact CB-CD2 4.46Å; I323-F379 HydrophobicContact CB-CE1 4.33Å; I323-F379 HydrophobicContact CB-CE2 4.25Å; I323-F379 HydrophobicContact CB-CZ 4.17Å; I323-F379 HydrophobicContact CD1-CD2 3.94Å; I323-F379 HydrophobicContact CD1-CE2 4.02Å; I323-F379 HydrophobicContact CG2-CB 4.42Å; I323-F379 HydrophobicContact CG2-CD1 3.57Å; I323-F379 HydrophobicContact CG2-CD2 4.04Å; I323-F379 HydrophobicContact CG2-CE1 3.71Å; I323-F379 HydrophobicContact CG2-CE2 4.18Å; I323-F379 HydrophobicContact CG2-CG 3.76Å; I323-F379 HydrophobicContact CG2-CZ 4.03Å; I324-F379 HydrophobicContact CD1-CE1 4.45Å; I324-F379 HydrophobicContact CD1-CZ 4.05Å; I324-F379 HydrophobicContact CG1-CE1 3.72Å; I324-F379 HydrophobicContact CG1-CZ 3.68Å; L327-F379 HydrophobicContact CD1-CD1 4.22Å; L327-F379 HydrophobicContact CD1-CE1 4.47Å; H375-F379 WeakPolarHBondContact O-CD2 3.33Å; H375-F379 VanDerWaalsContact O-CE2 3.3Å; H375-F379 WeakPolarHBondContact O-CE2 3.4Å; L376-F379 PolarHBondContact O-N 2.99Å; G377-F379 PolarHBondContact O-N 3.43Å; F379-K381 VanDerWaalsContact C-N 3.3Å; F379-K381 PolarHBondContact O-N 2.64Å; F379-F382 PolarHBondContact O-N 2.91Å; F379-F382 VanDerWaalsContact O-N 3.11Å; F379-I383 HydrophobicContact CB-CD1 3.85Å; F379-I383 HydrophobicContact CD1-CD1 3.86Å; F379-I383 HydrophobicContact CG-CD1 4.32Å; F379-I383 WeakPolarHBondContact O-CB 3.32Å; F379-I383 VanDerWaalsContact O-CG1 3.31Å; F379-I383 WeakPolarHBondContact O-CG1 3.3Å; F379-I383 PolarHBondContact O-N 2.9Å; F379-V403 HydrophobicContact CE1-CG1 4.22Å; F379-V415 HydrophobicContact CD1-CB 4.32Å; F379-V415 HydrophobicContact CD1-CG1 4.32Å; F379-V415 HydrophobicContact CD1-CG2 3.88Å; F379-V415 HydrophobicContact CE1-CB 3.83Å; F379-V415 HydrophobicContact CE1-CG1 3.66Å; F379-V415 HydrophobicContact CE1-CG2 3.93Å; F379-V415 HydrophobicContact CE2-CG1 4.23Å; F379-V415 HydrophobicContact CZ-CB 4.29Å; F379-V415 HydrophobicContact CZ-CG1 3.6Å; F379-I445 HydrophobicContact CE2-CD1 3.96Å; F379-I445 HydrophobicContact CZ-CD1 4.35Å
380S89.9Confident93.8Very high0 Ų030.3 Ų30.30%015%0.145CC..Hα-helixtrans-54.5-44.4-177.547.70000112.3I70 R126 L376 G377 F382I70-S380 CarbonylContact O-C 3.44Å; I70-S380 VanDerWaalsContact O-CB 3.3Å; I70-S380 WeakPolarHBondContact O-CB 3.48Å; I70-S380 PolarHBondContact O-OG 3.39Å; I70-S380 VanDerWaalsContact O-OG 3.09Å; R126-S380 PolarHBondContact NH1-O 2.98Å; L376-S380 PolarHBondContact O-N 3.48Å; L376-S380 PolarHBondContact O-OG 3.09Å; G377-S380 WeakPolarHBondContact CA-OG 3.5Å; S380-F382 VanDerWaalsContact C-N 3.34Å; S380-F382 PolarHBondContact O-N 2.88Å
381K90.6Very high93.8Very high65 Ų6531.1 Ų31.128%0.28316%0.155SC..THydrogen-bonded Turntrans-67.6-38.9-178.4-169.8175.6-179.563.50111.8G67 G69 I70 R126 G377 F379G67-K381 PolarHBondContact O-NZ 3.29Å; G69-K381 PolarHBondContact O-NZ 2.92Å; I70-K381 WeakPolarHBondContact O-CA 3.35Å; I70-K381 PolarHBondContact O-N 3.19Å; R126-K381 PolarHBondContact NH2-O 2.73Å; G377-K381 WeakPolarHBondContact O-CB 3.49Å; G377-K381 PolarHBondContact O-N 3.03Å; F379-K381 VanDerWaalsContact C-N 3.3Å; F379-K381 PolarHBondContact O-N 2.64Å
382F94.6Very high93.6Very high60 Ų6032.3 Ų32.326%0.26316%0.16SC..THydrogen-bonded Turntrans-106.8-3-163.3-60.7-59.5000114.4F379 S380 H407 V413 T447 L449F379-F382 PolarHBondContact O-N 2.91Å; F379-F382 VanDerWaalsContact O-N 3.11Å; S380-F382 VanDerWaalsContact C-N 3.34Å; S380-F382 PolarHBondContact O-N 2.88Å; F382-H407 PolarHBondContact O-CE1 2.97Å; F382-H407 PolarHBondContact O-NE2 3.49Å; F382-V413 HydrophobicContact CB-CG2 4.28Å; F382-T447 HydrophobicContact CB-CG2 3.69Å; F382-T447 HydrophobicContact CD2-CG2 3.63Å; F382-T447 HydrophobicContact CE2-CG2 4.43Å; F382-T447 HydrophobicContact CG-CG2 3.8Å; F382-L449 HydrophobicContact CB-CD1 4.41Å; F382-L449 HydrophobicContact CD1-CD1 3.51Å; F382-L449 HydrophobicContact CE1-CD1 4Å; F382-L449 HydrophobicContact CG-CD1 4.17Å
383I94.6Very high93.6Very high1 Ų136.5 Ų36.51%0.00519%0.185CC..SBendtrans-129.489.3-179.1-42.2166.1000108.3I20 F379 S387 L405 V413 V415I20-I383 WeakPolarHBondContact CB-O 3.42Å; I20-I383 HydrophobicContact CD1-CB 3.28Å; I20-I383 HydrophobicContact CD1-CD1 3.84Å; I20-I383 HydrophobicContact CD1-CG1 4.17Å; I20-I383 HydrophobicContact CD1-CG2 3.07Å; I20-I383 HydrophobicContact CG1-CB 4.47Å; I20-I383 HydrophobicContact CG1-CG2 4.45Å; I20-I383 HydrophobicContact CG2-CB 4.48Å; F379-I383 HydrophobicContact CB-CD1 3.85Å; F379-I383 HydrophobicContact CD1-CD1 3.86Å; F379-I383 HydrophobicContact CG-CD1 4.32Å; F379-I383 WeakPolarHBondContact O-CB 3.32Å; F379-I383 VanDerWaalsContact O-CG1 3.31Å; F379-I383 WeakPolarHBondContact O-CG1 3.3Å; F379-I383 PolarHBondContact O-N 2.9Å; I383-S387 VanDerWaalsContact CG2-CB 3.48Å; I383-S387 WeakPolarHBondContact CG2-OG 3.42Å; I383-L405 HydrophobicContact CD1-CD1 3.8Å; I383-L405 HydrophobicContact CG1-CD1 4.43Å; I383-L405 HydrophobicContact CG2-CB 4.38Å; I383-L405 HydrophobicContact CG2-CD1 4.33Å; I383-L405 HydrophobicContact CG2-CD2 3.85Å; I383-L405 HydrophobicContact CG2-CG 4.4Å; I383-V413 HydrophobicContact CG1-CG1 4.07Å; I383-V413 HydrophobicContact CG1-CG2 4.16Å; I383-V413 HydrophobicContact CG2-CG1 4.28Å; I383-V415 HydrophobicContact CD1-CG2 4.34Å
384P89.5Confident93.7Very high33 Ų3338.6 Ų38.621%0.21420%0.203CC..  trans-69.8162.4-17830.2-35.5000112.2G386 S387P384-G386 PolarHBondContact O-N 3.49Å; P384-S387 WeakPolarHBondContact CD-OG 3.31Å; P384-S387 VanDerWaalsContact O-CB 3.32Å; P384-S387 WeakPolarHBondContact O-CB 3.43Å; P384-S387 PolarHBondContact O-N 2.89Å; P384-S387 VanDerWaalsContact O-N 3.15Å; P384-S387 PolarHBondContact O-OG 3.32Å
385E89.1Confident93.7Very high84 Ų8438.4 Ų38.439%0.39322%0.218SC..THydrogen-bonded Turntrans-53.4137.1173.2-177.4176.5-179.700111.9V18 S387V18-E385 WeakPolarHBondContact O-CA 3.26Å; E385-S387 VanDerWaalsContact C-N 3.32Å
386G88.9Confident93.5Very high25 Ų2545.4 Ų45.426%0.25825%0.251SS..THydrogen-bonded Turntrans89.8-3.3-17800000113.6V18 P384V18-G386 PolarHBondContact O-N 3.36Å; P384-G386 PolarHBondContact O-N 3.49Å
387S93.2Very high93.5Very high0 Ų054.7 Ų54.70%029%0.291CS..BIsolated β-bridgetrans-60148.7168.6-600000110.6V18 I383 P384 E385 M406 H407V18-S387 VanDerWaalsContact CB-O 3.23Å; V18-S387 WeakPolarHBondContact CB-O 3.19Å; V18-S387 VanDerWaalsContact CG2-O 3.29Å; V18-S387 WeakPolarHBondContact CG2-O 3.05Å; V18-S387 PolarHBondContact N-O 3.28Å; I383-S387 VanDerWaalsContact CG2-CB 3.48Å; I383-S387 WeakPolarHBondContact CG2-OG 3.42Å; P384-S387 WeakPolarHBondContact CD-OG 3.31Å; P384-S387 VanDerWaalsContact O-CB 3.32Å; P384-S387 WeakPolarHBondContact O-CB 3.43Å; P384-S387 PolarHBondContact O-N 2.89Å; P384-S387 VanDerWaalsContact O-N 3.15Å; P384-S387 PolarHBondContact O-OG 3.32Å; E385-S387 VanDerWaalsContact C-N 3.32Å; S387-M406 CarbonylContact C-O 3.46Å; S387-M406 WeakPolarHBondContact CA-O 3.38Å; S387-M406 WeakPolarHBondContact CB-O 3.33Å; S387-H407 PolarHBondContact OG-CD2 2.65Å
388Q93Very high93.6Very high83 Ų8357.2 Ų57.239%0.38830%0.304SS..EExtended strand (participates in β ladder)trans-122.1126.1-177.8-171.5176.324.900110.3P14 L405 M406P14-Q388 VanDerWaalsContact CG-NE2 3.3Å; Q388-L405 CarbonylContact O-C 3.59Å; Q388-L405 WeakPolarHBondContact O-CA 3.19Å; Q388-L405 WeakPolarHBondContact O-CB 3.48Å; Q388-M406 PolarHBondContact N-O 3.04Å; Q388-M406 PolarHBondContact O-N 3.42Å
389R95.6Very high93.6Very high88 Ų8860.8 Ų60.833%0.33233%0.325SS..EExtended strand (participates in β ladder)trans-65.9134.7172.7-172.5-154.671.696.4-0.5110.4L327 V403 A404 L405L327-R389 WeakPolarHBondContact O-CD 3.43Å; R389-V403 HydrophobicContact CG-CG2 4.09Å; R389-A404 WeakPolarHBondContact CA-O 3.19Å; R389-L405 HydrophobicContact CB-CD2 4.24Å; R389-L405 HydrophobicContact CB-CG 4.33Å
390V93.9Very high93.6Very high11 Ų1161.7 Ų61.77%0.06733%0.329CS..EExtended strand (participates in β ladder)trans-122.8175177.8-630000111.5F3 A404 M406F3-V390 HydrophobicContact CD1-CG2 4.31Å; F3-V390 HydrophobicContact CD2-CG2 4.41Å; F3-V390 HydrophobicContact CE1-CG2 3.61Å; F3-V390 HydrophobicContact CE2-CG2 3.75Å; F3-V390 HydrophobicContact CZ-CG2 3.31Å; V390-A404 HydrophobicContact CG2-CB 3.96Å; V390-A404 PolarHBondContact N-O 3.21Å; V390-M406 HydrophobicContact CG1-CB 4.47Å; V390-M406 HydrophobicContact CG1-CG 3.93Å; V390-M406 HydrophobicContact CG1-SD 4.12Å; V390-M406 HydrophobicContact CG2-CG 4.32Å
391G94.1Very high94Very high22 Ų2263.1 Ų63.123%0.22734%0.337CS..EExtended strand (participates in β ladder)trans-71.9135.2-179.800000112.2S4S4-G391 PolarHBondContact N-O 3.44Å; S4-G391 WeakPolarHBondContact OG-CA 3.5Å
392L95.3Very high94.4Very high40 Ų4060.9 Ų60.921%0.20933%0.33CS..EExtended strand (participates in β ladder)trans-134.9107.7171.1-174.766000108.4M1 E2 A402 A404 V414M1-L392 HydrophobicContact CB-CD1 3.64Å; M1-L392 HydrophobicContact CB-CG 4Å; M1-L392 HydrophobicContact SD-CD2 3.8Å; M1-L392 HydrophobicContact SD-CG 4.2Å; E2-L392 WeakPolarHBondContact O-CA 3.39Å; L392-A402 HydrophobicContact CD2-CB 3.82Å; L392-A404 HydrophobicContact CB-CB 3.82Å; L392-A404 HydrophobicContact CD1-CB 4.34Å; L392-A404 HydrophobicContact CD2-CB 4.14Å; L392-A404 HydrophobicContact CG-CB 4.33Å; L392-V414 HydrophobicContact CD2-CG1 4.1Å
393V96.1Very high94.6Very high89 Ų8958 Ų5854%0.53932%0.318SS..EExtended strand (participates in β ladder)trans-103.1128-174.2-175.50000109.8M1 E2M1-V393 CarbonylContact C-O 3.58Å; M1-V393 WeakPolarHBondContact CA-O 3.34Å; E2-V393 PolarHBondContact N-O 3.38Å; E2-V393 PolarHBondContact O-N 2.84Å
394A95.8Very high94.7Very high46 Ų4658 Ų5838%0.3832%0.318SS..  trans-81.2135.9171.500000110.2Q396 N398A394-Q396 WeakPolarHBondContact CB-O 3.42Å; A394-Q396 PolarHBondContact O-N 3.37Å; A394-N398 WeakPolarHBondContact CB-ND2 3.4Å
395S95.1Very high95.1Very high111 Ų11156.5 Ų56.578%0.77631%0.308SS*.SBendtrans-69.1-21.3176.750.20000113
396Q93.8Very high95.4Very high147 Ų14754.3 Ų54.369%0.68730%0.298SS*.SBendtrans-153.8163.7-179.562.1-173.465.300110.7A394 N398A394-Q396 WeakPolarHBondContact CB-O 3.42Å; A394-Q396 PolarHBondContact O-N 3.37Å; Q396-N398 PolarHBondContact O-N 2.71Å; Q396-N398 PolarHBondContact O-ND2 3.06Å
397K94.6Very high95.7Very high195 Ų19554.5 Ų54.585%0.84829%0.292SS*.  trans-59.2135.6171-172.1179178.9-1760110
398N95.6Very high95.7Very high59 Ų5958.9 Ų58.932%0.31632%0.321SS..  trans-153.8168.9178.864.889.6000109.6A394 Q396 L400A394-N398 WeakPolarHBondContact CB-ND2 3.4Å; Q396-N398 PolarHBondContact O-N 2.71Å; Q396-N398 PolarHBondContact O-ND2 3.06Å; N398-L400 VanDerWaalsContact OD1-CB 3.29Å; N398-L400 WeakPolarHBondContact OD1-CB 3.41Å; N398-L400 PolarHBondContact OD1-N 2.88Å; N398-L400 VanDerWaalsContact OD1-N 3.09Å
399D95.4Very high95.8Very high118 Ų11860.6 Ų60.663%0.63133%0.333SS*.SBendtrans-100.315.1-175.8-58.6-36.6000112.9
400L98Very high95.8Very high19 Ų1957.5 Ų57.510%0.09933%0.328CS..EExtended strand (participates in β ladder)trans-89.3138.6178.6-55.2177.5000110.6M1 N398 V416 N418 V424M1-L400 HydrophobicContact CE-CB 4.14Å; M1-L400 HydrophobicContact CE-CD1 3.79Å; N398-L400 VanDerWaalsContact OD1-CB 3.29Å; N398-L400 WeakPolarHBondContact OD1-CB 3.41Å; N398-L400 PolarHBondContact OD1-N 2.88Å; N398-L400 VanDerWaalsContact OD1-N 3.09Å; L400-V416 HydrophobicContact CB-CG1 4.31Å; L400-V416 HydrophobicContact CD1-CG1 4.03Å; L400-N418 HydrophobicContact CD2-CB 3.53Å; L400-V424 HydrophobicContact CD1-CB 4.32Å; L400-V424 HydrophobicContact CD1-CG1 3.94Å; L400-V424 HydrophobicContact CD2-CB 4.3Å; L400-V424 HydrophobicContact CD2-CG2 4.19Å; L400-V424 HydrophobicContact CG-CG1 4.41Å
401D98.4Very high96Very high30 Ų3057.8 Ų57.816%0.1633%0.331CS..EExtended strand (participates in β ladder)trans-93.2125.1165.5-58.8-57.4000107.7H321 I324 L417 R419H321-D401 IonicContact CE1-OD1 3.31Å; H321-D401 IonicContact CE1-OD2 3.33Å; H321-D401 IonicContact CG-OD2 2.93Å; H321-D401 IonicContact ND1-OD1 3.98Å; H321-D401 PolarHBondContact ND1-OD1 3.15Å; H321-D401 IonicContact ND1-OD2 3.67Å; H321-D401 PolarHBondContact ND1-OD2 3.2Å; I324-D401 HydrophobicContact CD1-CB 3.78Å; I324-D401 HydrophobicContact CG2-CB 4.11Å; D401-L417 HydrophobicContact CB-CB 4.23Å; D401-L417 HydrophobicContact CB-CD2 4.33Å; D401-L417 PolarHBondContact N-O 3.02Å; D401-L417 PolarHBondContact O-N 3.49Å; D401-R419 IonicContact OD1-NH2 3.54Å; D401-R419 IonicContact OD2-CZ 2.68Å; D401-R419 IonicContact OD2-NE 3.85Å; D401-R419 PolarHBondContact OD2-NE 2.99Å; D401-R419 IonicContact OD2-NH2 2.63Å; D401-R419 PolarHBondContact OD2-NH2 3.05Å
402A98.4Very high96.1Very high17 Ų1756.8 Ų56.814%0.1432%0.32CS..EExtended strand (participates in β ladder)trans-142.8147.1-17800000112.8M1 L392 V415 V416M1-A402 HydrophobicContact CE-CB 3.87Å; M1-A402 HydrophobicContact SD-CB 3.71Å; L392-A402 HydrophobicContact CD2-CB 3.82Å; A402-V415 VanDerWaalsContact CA-O 3.25Å; A402-V415 WeakPolarHBondContact CA-O 3.39Å; A402-V416 HydrophobicContact CB-CG2 4.23Å
403V98.3Very high96.3Very high1 Ų154.9 Ų54.91%0.00631%0.31CS..EExtended strand (participates in β ladder)trans-142.2140.6175.866.50000110.6I324 L327 L328 F379 R389 L405 V414 V415I324-V403 HydrophobicContact CG1-CG1 4.08Å; I324-V403 HydrophobicContact CG2-CB 4.36Å; L327-V403 HydrophobicContact CB-CG2 4.05Å; L327-V403 HydrophobicContact CD1-CG1 4.09Å; L327-V403 HydrophobicContact CD1-CG2 4.35Å; L328-V403 HydrophobicContact CD2-CG2 4.3Å; F379-V403 HydrophobicContact CE1-CG1 4.22Å; R389-V403 HydrophobicContact CG-CG2 4.09Å; V403-L405 HydrophobicContact CG1-CD1 4.17Å; V403-L405 HydrophobicContact CG2-CD1 4.11Å; V403-V414 WeakPolarHBondContact O-CA 3.21Å; V403-V415 HydrophobicContact CG1-CB 4.17Å; V403-V415 PolarHBondContact N-O 3.41Å; V403-V415 PolarHBondContact O-N 2.75Å
404A97.4Very high96.4Very high1 Ų150.6 Ų50.61%0.00828%0.284CS..EExtended strand (participates in β ladder)trans-116.8137.3177.200000110.9F3 R389 V390 L392 V413 V414F3-A404 HydrophobicContact CD2-CB 3.9Å; F3-A404 HydrophobicContact CE2-CB 3.64Å; R389-A404 WeakPolarHBondContact CA-O 3.19Å; V390-A404 HydrophobicContact CG2-CB 3.96Å; V390-A404 PolarHBondContact N-O 3.21Å; L392-A404 HydrophobicContact CB-CB 3.82Å; L392-A404 HydrophobicContact CD1-CB 4.34Å; L392-A404 HydrophobicContact CD2-CB 4.14Å; L392-A404 HydrophobicContact CG-CB 4.33Å; A404-V413 WeakPolarHBondContact CA-O 3.34Å; A404-V414 HydrophobicContact CB-CG2 3.89Å
405L97.6Very high96.5Very high0 Ų048.4 Ų48.40%027%0.266CS..EExtended strand (participates in β ladder)trans-136.6158.8173.8-48.591.4000110.5V18 I20 I383 Q388 R389 V403 V413V18-L405 HydrophobicContact CG1-CD2 4.5Å; V18-L405 HydrophobicContact CG2-CD2 4.43Å; I20-L405 HydrophobicContact CD1-CD2 4.44Å; I383-L405 HydrophobicContact CD1-CD1 3.8Å; I383-L405 HydrophobicContact CG1-CD1 4.43Å; I383-L405 HydrophobicContact CG2-CB 4.38Å; I383-L405 HydrophobicContact CG2-CD1 4.33Å; I383-L405 HydrophobicContact CG2-CD2 3.85Å; I383-L405 HydrophobicContact CG2-CG 4.4Å; Q388-L405 CarbonylContact O-C 3.59Å; Q388-L405 WeakPolarHBondContact O-CA 3.19Å; Q388-L405 WeakPolarHBondContact O-CB 3.48Å; R389-L405 HydrophobicContact CB-CD2 4.24Å; R389-L405 HydrophobicContact CB-CG 4.33Å; V403-L405 HydrophobicContact CG1-CD1 4.17Å; V403-L405 HydrophobicContact CG2-CD1 4.11Å; L405-V413 HydrophobicContact CB-CG1 3.74Å; L405-V413 HydrophobicContact CD1-CG1 4.16Å; L405-V413 PolarHBondContact N-O 2.92Å; L405-V413 PolarHBondContact O-N 3.08Å
406M96Very high96.7Very high39 Ų3943.1 Ų43.119%0.19223%0.229CC..EExtended strand (participates in β ladder)trans-109.7135.4168.6-71.4-172.861.800109.8F3 S387 Q388 V390 S411F3-M406 HydrophobicContact CE1-CG 4.07Å; F3-M406 HydrophobicContact CE1-SD 4.21Å; F3-M406 HydrophobicContact CZ-CG 3.84Å; S387-M406 CarbonylContact C-O 3.46Å; S387-M406 WeakPolarHBondContact CA-O 3.38Å; S387-M406 WeakPolarHBondContact CB-O 3.33Å; Q388-M406 PolarHBondContact N-O 3.04Å; Q388-M406 PolarHBondContact O-N 3.42Å; V390-M406 HydrophobicContact CG1-CB 4.47Å; V390-M406 HydrophobicContact CG1-CG 3.93Å; V390-M406 HydrophobicContact CG1-SD 4.12Å; V390-M406 HydrophobicContact CG2-CG 4.32Å; M406-S411 WeakPolarHBondContact CA-O 3.4Å
407H95.3Very high97Very high28 Ų2836.1 Ų36.113%0.1320%0.196CC..  trans-73.7162.1172.3-70.6176.9000111.6F382 S387 D409 G410 S411 V413F382-H407 PolarHBondContact O-CE1 2.97Å; F382-H407 PolarHBondContact O-NE2 3.49Å; S387-H407 PolarHBondContact OG-CD2 2.65Å; H407-D409 WeakPolarHBondContact CB-OD1 3.32Å; H407-D409 PolarHBondContact O-N 3.28Å; H407-D409 VanDerWaalsContact O-N 3.16Å; H407-G410 PolarHBondContact O-N 2.78Å; H407-S411 WeakPolarHBondContact CB-OG 3.39Å; H407-S411 PolarHBondContact N-O 2.94Å; H407-S411 PolarHBondContact ND1-OG 3.44Å; H407-V413 WeakPolarHBondContact NE2-CG1 3.28Å
408P92.8Very high97.1Very high92 Ų9226.9 Ų26.960%0.59716%0.156SC*.THydrogen-bonded Turntrans-56.7-27.3173.8-26.735.5000114.5G410P408-G410 VanDerWaalsContact C-N 3.28Å
409D95Very high97.3Very high120 Ų12029 Ų2964%0.64216%0.16SC*.THydrogen-bonded Turntrans-83.2-1.3177.370.3-0.3000113.9H407 S411H407-D409 WeakPolarHBondContact CB-OD1 3.32Å; H407-D409 PolarHBondContact O-N 3.28Å; H407-D409 VanDerWaalsContact O-N 3.16Å; D409-S411 VanDerWaalsContact OD1-CB 3.28Å; D409-S411 WeakPolarHBondContact OD1-CB 3.41Å; D409-S411 PolarHBondContact OD1-N 3.35Å; D409-S411 PolarHBondContact OD1-OG 3.08Å
410G95.6Very high97.4Very high23 Ų2324.8 Ų24.824%0.23714%0.139CC..SBendtrans86.8-1.5-179.200000115.3H407 P408 R452H407-G410 PolarHBondContact O-N 2.78Å; P408-G410 VanDerWaalsContact C-N 3.28Å; G410-R452 VanDerWaalsContact O-CD 3.24Å; G410-R452 WeakPolarHBondContact O-CD 3.36Å; G410-R452 WeakPolarHBondContact O-CG 3.21Å
411S97.1Very high97.4Very high17 Ų1727.6 Ų27.612%0.11916%0.161CC..  trans-68.3156170.462.40000111.9M406 H407 D409 W450M406-S411 WeakPolarHBondContact CA-O 3.4Å; H407-S411 WeakPolarHBondContact CB-OG 3.39Å; H407-S411 PolarHBondContact N-O 2.94Å; H407-S411 PolarHBondContact ND1-OG 3.44Å; D409-S411 VanDerWaalsContact OD1-CB 3.28Å; D409-S411 WeakPolarHBondContact OD1-CB 3.41Å; D409-S411 PolarHBondContact OD1-N 3.35Å; D409-S411 PolarHBondContact OD1-OG 3.08Å; S411-W450 WeakPolarHBondContact CB-O 3.16Å
412A97.8Very high97.4Very high0 Ų033.5 Ų33.50%019%0.185CC..EExtended strand (participates in β ladder)trans-104.3145.5-178.600000111.6F3 L449 W450 R452F3-A412 HydrophobicContact CE2-CB 4.13Å; F3-A412 HydrophobicContact CZ-CB 3.96Å; A412-L449 WeakPolarHBondContact O-CA 3.46Å; A412-W450 HydrophobicContact CB-CD2 3.89Å; A412-W450 VanDerWaalsContact CB-CE2 3.41Å; A412-W450 HydrophobicContact CB-CE3 4.35Å; A412-W450 HydrophobicContact CB-CG 4.46Å; A412-W450 HydrophobicContact CB-CH2 3.98Å; A412-W450 HydrophobicContact CB-CZ2 3.46Å; A412-W450 VanDerWaalsContact CB-CZ2 3.46Å; A412-W450 HydrophobicContact CB-CZ3 4.39Å; A412-W450 PolarHBondContact N-O 2.82Å; A412-W450 PolarHBondContact O-N 3.05Å; A412-R452 HydrophobicContact CB-CG 4.19Å
413V98Very high97.4Very high0 Ų037.5 Ų37.50%020%0.204CC..EExtended strand (participates in β ladder)trans-131133.3170.861.70000110.3F382 I383 A404 L405 H407 T447 Y448 L449F382-V413 HydrophobicContact CB-CG2 4.28Å; I383-V413 HydrophobicContact CG1-CG1 4.07Å; I383-V413 HydrophobicContact CG1-CG2 4.16Å; I383-V413 HydrophobicContact CG2-CG1 4.28Å; A404-V413 WeakPolarHBondContact CA-O 3.34Å; L405-V413 HydrophobicContact CB-CG1 3.74Å; L405-V413 HydrophobicContact CD1-CG1 4.16Å; L405-V413 PolarHBondContact N-O 2.92Å; L405-V413 PolarHBondContact O-N 3.08Å; H407-V413 WeakPolarHBondContact NE2-CG1 3.28Å; V413-T447 HydrophobicContact CG2-CG2 3.6Å; V413-Y448 CarbonylContact C-O 3.46Å; V413-Y448 VanDerWaalsContact CA-O 3.31Å; V413-Y448 WeakPolarHBondContact CA-O 3.26Å; V413-L449 HydrophobicContact CB-CD2 3.57Å; V413-L449 HydrophobicContact CG2-CD2 3.59Å; V413-L449 HydrophobicContact CG2-CG 4.37Å
414V98.6Very high97.4Very high0 Ų039.3 Ų39.30%022%0.215CC..EExtended strand (participates in β ladder)trans-129.5126.9172.91770000109.5F3 L392 V403 A404 V416 I428 T447 Y448 W450F3-V414 HydrophobicContact CD2-CG2 4.4Å; F3-V414 HydrophobicContact CE2-CG2 4.27Å; L392-V414 HydrophobicContact CD2-CG1 4.1Å; V403-V414 WeakPolarHBondContact O-CA 3.21Å; A404-V414 HydrophobicContact CB-CG2 3.89Å; V414-V416 HydrophobicContact CG1-CG2 3.86Å; V414-I428 HydrophobicContact CB-CD1 4.42Å; V414-I428 HydrophobicContact CG1-CD1 4.11Å; V414-T447 CarbonylContact O-C 3.52Å; V414-T447 WeakPolarHBondContact O-CA 3.44Å; V414-Y448 PolarHBondContact N-O 2.81Å; V414-Y448 PolarHBondContact O-N 3.16Å; V414-W450 HydrophobicContact CB-CH2 4.38Å; V414-W450 HydrophobicContact CB-CZ3 4.3Å; V414-W450 HydrophobicContact CG2-CH2 3.52Å; V414-W450 HydrophobicContact CG2-CZ3 3.9Å
415V98.7Very high97.4Very high0 Ų044.3 Ų44.30%025%0.247CC..EExtended strand (participates in β ladder)trans-104.2131.2171.1-172.80000108.7H378 F379 I383 A402 V403 I445 H446 T447H378-V415 HydrophobicContact CB-CG1 4.48Å; F379-V415 HydrophobicContact CD1-CB 4.32Å; F379-V415 HydrophobicContact CD1-CG1 4.32Å; F379-V415 HydrophobicContact CD1-CG2 3.88Å; F379-V415 HydrophobicContact CE1-CB 3.83Å; F379-V415 HydrophobicContact CE1-CG1 3.66Å; F379-V415 HydrophobicContact CE1-CG2 3.93Å; F379-V415 HydrophobicContact CE2-CG1 4.23Å; F379-V415 HydrophobicContact CZ-CB 4.29Å; F379-V415 HydrophobicContact CZ-CG1 3.6Å; I383-V415 HydrophobicContact CD1-CG2 4.34Å; A402-V415 VanDerWaalsContact CA-O 3.25Å; A402-V415 WeakPolarHBondContact CA-O 3.39Å; V403-V415 HydrophobicContact CG1-CB 4.17Å; V403-V415 PolarHBondContact N-O 3.41Å; V403-V415 PolarHBondContact O-N 2.75Å; V415-I445 HydrophobicContact CG1-CD1 4.1Å; V415-I445 HydrophobicContact CG1-CG1 4.09Å; V415-H446 CarbonylContact C-O 3.57Å; V415-H446 WeakPolarHBondContact CA-O 3.27Å; V415-T447 HydrophobicContact CG2-CG2 4Å
416V98.8Very high97.4Very high0 Ų045.2 Ų45.20%025%0.252CS..EExtended strand (participates in β ladder)trans-126.5125.1177.6-1760000108.8L400 A402 V414 L426 I445 H446 Y448L400-V416 HydrophobicContact CB-CG1 4.31Å; L400-V416 HydrophobicContact CD1-CG1 4.03Å; A402-V416 HydrophobicContact CB-CG2 4.23Å; V414-V416 HydrophobicContact CG1-CG2 3.86Å; V416-L426 HydrophobicContact CG2-CD1 4.4Å; V416-I445 CarbonylContact O-C 3.52Å; V416-I445 WeakPolarHBondContact O-CA 3.12Å; V416-H446 PolarHBondContact N-O 3.49Å; V416-H446 PolarHBondContact O-N 3.02Å; V416-Y448 HydrophobicContact CB-CE2 4.36Å; V416-Y448 HydrophobicContact CG2-CD2 4.3Å; V416-Y448 HydrophobicContact CG2-CE2 3.97Å
417L98.8Very high97.5Very high0 Ų046 Ų460%026%0.259CS..EExtended strand (participates in β ladder)trans-113.8126.8175.8170.771.3000109.3M317 S320 H321 I324 D401 R419 I445M317-L417 HydrophobicContact CG-CD1 4.31Å; S320-L417 WeakPolarHBondContact OG-CD1 3.28Å; S320-L417 VanDerWaalsContact OG-CD2 3.27Å; S320-L417 WeakPolarHBondContact OG-CD2 3.17Å; H321-L417 HydrophobicContact CB-CD2 3.89Å; I324-L417 HydrophobicContact CD1-CB 3.81Å; I324-L417 HydrophobicContact CD1-CD2 4.38Å; D401-L417 HydrophobicContact CB-CB 4.23Å; D401-L417 HydrophobicContact CB-CD2 4.33Å; D401-L417 PolarHBondContact N-O 3.02Å; D401-L417 PolarHBondContact O-N 3.49Å; L417-R419 HydrophobicContact CD1-CG 4.18Å; L417-R419 HydrophobicContact CD2-CG 3.75Å; L417-R419 HydrophobicContact CG-CG 3.77Å; L417-I445 HydrophobicContact CD1-CB 4.01Å
418N98.6Very high97.7Very high0 Ų044.7 Ų44.70%025%0.253CS..EExtended strand (participates in β ladder)trans-110.4107170-173.1-2.1000109.8L400 S420 K422 S440 P441 Y443 S444L400-N418 HydrophobicContact CD2-CB 3.53Å; N418-S420 WeakPolarHBondContact OD1-CB 3.24Å; N418-S420 PolarHBondContact OD1-N 3.25Å; N418-S420 PolarHBondContact OD1-O 3.01Å; N418-S420 PolarHBondContact OD1-OG 2.85Å; N418-K422 PolarHBondContact ND2-O 3.4Å; N418-S440 WeakPolarHBondContact CB-OG 3.45Å; N418-S440 PolarHBondContact ND2-O 2.86Å; N418-P441 WeakPolarHBondContact CB-O 3.48Å; N418-P441 PolarHBondContact ND2-O 2.92Å; N418-Y443 CarbonylContact O-C 3.42Å; N418-Y443 VanDerWaalsContact O-CA 3.24Å; N418-Y443 WeakPolarHBondContact O-CA 3.44Å; N418-Y443 PolarHBondContact O-N 3.45Å; N418-S444 PolarHBondContact N-O 3.04Å; N418-S444 PolarHBondContact O-N 3.31Å; N418-S444 VanDerWaalsContact O-N 3.14Å
419R98.3Very high97.9Very high105 Ų10543.6 Ų43.640%0.39624%0.239SC..  trans-89.1-6.7176.5-59.7-173.5-73.9127.52.2113.3M317 H321 D401 L417 Y443M317-R419 HydrophobicContact CB-CG 4.17Å; M317-R419 HydrophobicContact CG-CG 4.34Å; M317-R419 HydrophobicContact SD-CB 3.92Å; M317-R419 HydrophobicContact SD-CG 3.86Å; H321-R419 PolarHBondContact CE1-NH2 3.26Å; H321-R419 VanDerWaalsContact CE1-NH2 3.33Å; H321-R419 PolarHBondContact ND1-NE 2.98Å; H321-R419 PolarHBondContact ND1-NH2 2.91Å; D401-R419 IonicContact OD1-NH2 3.54Å; D401-R419 IonicContact OD2-CZ 2.68Å; D401-R419 IonicContact OD2-NE 3.85Å; D401-R419 PolarHBondContact OD2-NE 2.99Å; D401-R419 IonicContact OD2-NH2 2.63Å; D401-R419 PolarHBondContact OD2-NH2 3.05Å; L417-R419 HydrophobicContact CD1-CG 4.18Å; L417-R419 HydrophobicContact CD2-CG 3.75Å; L417-R419 HydrophobicContact CG-CG 3.77Å; R419-Y443 VanDerWaalsContact O-CE1 3.22Å; R419-Y443 WeakPolarHBondContact O-CE1 3.37Å
420S98.1Very high98Very high28 Ų2837.9 Ų37.920%0.19621%0.208CC..SBendtrans-83.6162.6177.284.80000110.7N418 K422 G442 Y443N418-S420 WeakPolarHBondContact OD1-CB 3.24Å; N418-S420 PolarHBondContact OD1-N 3.25Å; N418-S420 PolarHBondContact OD1-O 3.01Å; N418-S420 PolarHBondContact OD1-OG 2.85Å; S420-K422 PolarHBondContact O-N 3.09Å; S420-K422 PolarHBondContact OG-N 3.06Å; S420-K422 PolarHBondContact OG-O 3.39Å; S420-G442 CarbonylContact O-C 3.02Å; S420-G442 WeakPolarHBondContact O-CA 3.34Å; S420-Y443 PolarHBondContact O-N 2.89Å
421S97.9Very high98Very high79 Ų7940.5 Ų40.555%0.55222%0.221SC*.SBendtrans-81-0.8174.167.90000113.8
422K98.2Very high98Very high153 Ų15342.7 Ų42.767%0.66524%0.24SC*.SBendtrans-102.7135.4-173-63.6179.2-176.5175.50109.9N418 S420N418-K422 PolarHBondContact ND2-O 3.4Å; S420-K422 PolarHBondContact O-N 3.09Å; S420-K422 PolarHBondContact OG-N 3.06Å; S420-K422 PolarHBondContact OG-O 3.39Å
423D98.5Very high97.9Very high101 Ų10146.4 Ų46.454%0.5426%0.263SS..  trans-67.8135.2169.7-65.7-0.9000109.9I439 P441 G442D423-I439 HydrophobicContact CB-CD1 3.84Å; D423-I439 HydrophobicContact CB-CG1 4.19Å; D423-P441 VanDerWaalsContact OD1-CA 3.27Å; D423-P441 WeakPolarHBondContact OD1-CA 3.32Å; D423-G442 PolarHBondContact OD1-N 2.81Å
424V98.3Very high97.8Very high40 Ų4047.6 Ų47.624%0.24228%0.275CS..EExtended strand (participates in β ladder)trans-121.7104.9-179.5-176.60000108.9L400 L426 S440L400-V424 HydrophobicContact CD1-CB 4.32Å; L400-V424 HydrophobicContact CD1-CG1 3.94Å; L400-V424 HydrophobicContact CD2-CB 4.3Å; L400-V424 HydrophobicContact CD2-CG2 4.19Å; L400-V424 HydrophobicContact CG-CG1 4.41Å; V424-L426 WeakPolarHBondContact O-CD2 3.26Å; V424-L426 PolarHBondContact O-N 3.01Å; V424-S440 PolarHBondContact N-O 3.03Å; V424-S440 PolarHBondContact O-N 3.28Å
425P98.1Very high97.7Very high106 Ų10654.2 Ų54.269%0.68830%0.304SS*.EExtended strand (participates in β ladder)trans-59.1133.3166.2-21.133.1000109.6
426L97.8Very high97.7Very high18 Ų1856.5 Ų56.59%0.09432%0.316CS..EExtended strand (participates in β ladder)trans-141.8153.8175.872.4145.9000112.2M1 V416 V424 I428 T438M1-L426 HydrophobicContact CE-CD1 4.31Å; V416-L426 HydrophobicContact CG2-CD1 4.4Å; V424-L426 WeakPolarHBondContact O-CD2 3.26Å; V424-L426 PolarHBondContact O-N 3.01Å; L426-I428 HydrophobicContact CD1-CD1 4.29Å; L426-I428 HydrophobicContact CD1-CG1 3.93Å; L426-T438 HydrophobicContact CD1-CG2 4.23Å; L426-T438 HydrophobicContact CD2-CG2 3.77Å; L426-T438 HydrophobicContact CG-CG2 3.65Å; L426-T438 PolarHBondContact N-O 3.47Å; L426-T438 PolarHBondContact O-N 3.27Å
427T98.4Very high97.6Very high56 Ų5664.5 Ų64.534%0.34435%0.353SS..EExtended strand (participates in β ladder)trans-119.4128.3169.9-46.90000109M1 F435 L436 E437M1-T427 PolarHBondContact N-O 2.98Å; T427-F435 HydrophobicContact CG2-CB 3.84Å; T427-F435 HydrophobicContact CG2-CD1 3.82Å; T427-F435 HydrophobicContact CG2-CG 4.3Å; T427-L436 CarbonylContact C-O 3.46Å; T427-L436 VanDerWaalsContact CA-O 3.29Å; T427-L436 WeakPolarHBondContact CA-O 3.23Å; T427-E437 HydrophobicContact CG2-CG 4.07Å
428I98.3Very high97.6Very high0 Ų066.5 Ų66.50%037%0.366CS..EExtended strand (participates in β ladder)trans-99.6122.6171.2-56.4172.5000107.6V414 L426 F435 L436 Y448 W450V414-I428 HydrophobicContact CB-CD1 4.42Å; V414-I428 HydrophobicContact CG1-CD1 4.11Å; L426-I428 HydrophobicContact CD1-CD1 4.29Å; L426-I428 HydrophobicContact CD1-CG1 3.93Å; I428-F435 CarbonylContact O-C 3.6Å; I428-F435 WeakPolarHBondContact O-CA 3.33Å; I428-L436 HydrophobicContact CB-CB 4.35Å; I428-L436 PolarHBondContact N-O 3.21Å; I428-L436 PolarHBondContact O-N 3.11Å; I428-Y448 HydrophobicContact CD1-CD2 3.78Å; I428-Y448 HydrophobicContact CD1-CE2 4.09Å; I428-Y448 HydrophobicContact CD1-CG 4.14Å; I428-W450 HydrophobicContact CG2-CH2 3.97Å
429K98Very high97.6Very high69 Ų6970 Ų7030%0.338%0.384SS..EExtended strand (participates in β ladder)trans-104.2120.5177.2-179.4-171176.2-164.90109.7M1 E2 F3 G434 F435M1-K429 PolarHBondContact O-N 3.46Å; E2-K429 HydrophobicContact CG-CD 4.1Å; E2-K429 WeakPolarHBondContact OE1-CE 3.27Å; E2-K429 IonicContact OE1-NZ 4Å; E2-K429 PolarHBondContact OE1-NZ 3.31Å; F3-K429 WeakPolarHBondContact CB-O 3.47Å; F3-K429 PolarHBondContact N-O 2.86Å; K429-G434 WeakPolarHBondContact CA-O 3.13Å; K429-F435 HydrophobicContact CB-CD1 3.84Å; K429-F435 HydrophobicContact CB-CE1 3.87Å; K429-F435 HydrophobicContact CD-CD1 4.44Å; K429-F435 HydrophobicContact CD-CE1 3.64Å; K429-F435 HydrophobicContact CD-CZ 3.99Å; K429-F435 HydrophobicContact CG-CD1 3.93Å; K429-F435 HydrophobicContact CG-CE1 3.59Å; K429-F435 HydrophobicContact CG-CZ 4.08Å
430D97.3Very high97.6Very high0 Ų065 Ų650%037%0.365CS..EExtended strand (participates in β ladder)trans-104.2114.7162.2-174.8-21.9000108.1A432 V433 G434 W450 R452D430-A432 PolarHBondContact O-N 2.82Å; D430-A432 WeakPolarHBondContact OD1-CB 3.29Å; D430-A432 PolarHBondContact OD1-N 2.82Å; D430-V433 HydrophobicContact CB-CB 4.35Å; D430-V433 PolarHBondContact O-N 2.9Å; D430-G434 PolarHBondContact N-O 2.89Å; D430-G434 PolarHBondContact O-N 3.39Å; D430-W450 HydrophobicContact CB-CZ2 3.96Å; D430-W450 PolarHBondContact OD2-NE1 3.47Å; D430-R452 IonicContact OD1-CZ 2.64Å; D430-R452 IonicContact OD1-NE 2.68Å; D430-R452 PolarHBondContact OD1-NE 2.91Å; D430-R452 IonicContact OD1-NH2 3.11Å; D430-R452 PolarHBondContact OD1-NH2 3.5Å; D430-R452 IonicContact OD2-CZ 3.81Å; D430-R452 IonicContact OD2-NE 2.71Å; D430-R452 PolarHBondContact OD2-NE 3.1Å; D430-R452 IonicContact OD2-NH2 3.61Å
431P95.3Very high97.6Very high79 Ų7965.7 Ų65.751%0.51337%0.369SS..THydrogen-bonded Turntrans-54.4-23.5-179.3-26.934.6000114.9F3F3-P431 WeakPolarHBondContact O-CD 3.34Å; F3-P431 VanDerWaalsContact O-CG 3.28Å; F3-P431 WeakPolarHBondContact O-CG 2.88Å
432A95.6Very high97.7Very high62 Ų6262.9 Ų62.951%0.51235%0.352SS..THydrogen-bonded Turntrans-84-21.7178.900000114.1D430 R452D430-A432 PolarHBondContact O-N 2.82Å; D430-A432 WeakPolarHBondContact OD1-CB 3.29Å; D430-A432 PolarHBondContact OD1-N 2.82Å; A432-R452 VanDerWaalsContact CB-NH2 3.33Å
433V96.5Very high97.7Very high79 Ų7961.2 Ų61.248%0.47934%0.342SS..THydrogen-bonded Turntrans-124.1-37.4-169-172.90000112.6D430 R452D430-V433 HydrophobicContact CB-CB 4.35Å; D430-V433 PolarHBondContact O-N 2.9Å; V433-R452 HydrophobicContact CG2-CB 4.43Å
434G95.8Very high97.7Very high24 Ų2457 Ų5725%0.24732%0.32CS..EExtended strand (participates in β ladder)trans128.5-137.3-177.700000112.8K429 D430K429-G434 WeakPolarHBondContact CA-O 3.13Å; D430-G434 PolarHBondContact N-O 2.89Å; D430-G434 PolarHBondContact O-N 3.39Å
435F97.4Very high97.7Very high140 Ų14055.6 Ų55.661%0.61431%0.311SS*.EExtended strand (participates in β ladder)trans-122.7135.8-169.7-59.5-92.4000111.3T427 I428 K429T427-F435 HydrophobicContact CG2-CB 3.84Å; T427-F435 HydrophobicContact CG2-CD1 3.82Å; T427-F435 HydrophobicContact CG2-CG 4.3Å; I428-F435 CarbonylContact O-C 3.6Å; I428-F435 WeakPolarHBondContact O-CA 3.33Å; K429-F435 HydrophobicContact CB-CD1 3.84Å; K429-F435 HydrophobicContact CB-CE1 3.87Å; K429-F435 HydrophobicContact CD-CD1 4.44Å; K429-F435 HydrophobicContact CD-CE1 3.64Å; K429-F435 HydrophobicContact CD-CZ 3.99Å; K429-F435 HydrophobicContact CG-CD1 3.93Å; K429-F435 HydrophobicContact CG-CE1 3.59Å; K429-F435 HydrophobicContact CG-CZ 4.08Å
436L97.6Very high97.7Very high47 Ų4753.1 Ų53.125%0.24629%0.291CS..EExtended strand (participates in β ladder)trans-109.3105.9169.3-67.979.3000107.9T427 I428 W450T427-L436 CarbonylContact C-O 3.46Å; T427-L436 VanDerWaalsContact CA-O 3.29Å; T427-L436 WeakPolarHBondContact CA-O 3.23Å; I428-L436 HydrophobicContact CB-CB 4.35Å; I428-L436 PolarHBondContact N-O 3.21Å; I428-L436 PolarHBondContact O-N 3.11Å; L436-W450 HydrophobicContact CD2-CD2 4.44Å; L436-W450 HydrophobicContact CD2-CE3 3.99Å; L436-W450 HydrophobicContact CD2-CZ3 4.39Å
437E97.9Very high97.8Very high168 Ų16853.7 Ų53.779%0.78530%0.295SS*.EExtended strand (participates in β ladder)trans-84.3128.4172.4-64.9-175.2175.100109.9T427T427-E437 HydrophobicContact CG2-CG 4.07Å
438T98.3Very high97.8Very high43 Ų4352.6 Ų52.626%0.26429%0.285SS..EExtended strand (participates in β ladder)trans-155.3176.7-176.2-173.30000110.8L426 Y448L426-T438 HydrophobicContact CD1-CG2 4.23Å; L426-T438 HydrophobicContact CD2-CG2 3.77Å; L426-T438 HydrophobicContact CG-CG2 3.65Å; L426-T438 PolarHBondContact N-O 3.47Å; L426-T438 PolarHBondContact O-N 3.27Å; T438-Y448 HydrophobicContact CG2-CE1 3.98Å; T438-Y448 VanDerWaalsContact CG2-OH 3.26Å; T438-Y448 WeakPolarHBondContact CG2-OH 3.42Å; T438-Y448 PolarHBondContact OG1-OH 3.03Å
439I98.2Very high97.8Very high74 Ų7456.7 Ų56.738%0.37931%0.306SS..EExtended strand (participates in β ladder)trans-122.3142.5171.9-165.3168.3000108.7D423 P441 H446D423-I439 HydrophobicContact CB-CD1 3.84Å; D423-I439 HydrophobicContact CB-CG1 4.19Å; I439-P441 HydrophobicContact CG2-CG 4.4Å; I439-P441 WeakPolarHBondContact O-CD 3.38Å; I439-H446 PolarHBondContact O-CE1 2.9Å; I439-H446 VanDerWaalsContact O-CE1 3.31Å
440S98.5Very high97.8Very high0 Ų054.8 Ų54.80%030%0.297CS..EExtended strand (participates in β ladder)trans-105.595.6167.2-169.30000107.6N418 V424N418-S440 WeakPolarHBondContact CB-OG 3.45Å; N418-S440 PolarHBondContact ND2-O 2.86Å; V424-S440 PolarHBondContact N-O 3.03Å; V424-S440 PolarHBondContact O-N 3.28Å
441P98.7Very high97.8Very high42 Ų4264.8 Ų64.827%0.27333%0.334SS..  trans-56.7156.9179.8-24.434.2000112N418 D423 I439 Y443 S444 H446N418-P441 WeakPolarHBondContact CB-O 3.48Å; N418-P441 PolarHBondContact ND2-O 2.92Å; D423-P441 VanDerWaalsContact OD1-CA 3.27Å; D423-P441 WeakPolarHBondContact OD1-CA 3.32Å; I439-P441 HydrophobicContact CG2-CG 4.4Å; I439-P441 WeakPolarHBondContact O-CD 3.38Å; P441-Y443 PolarHBondContact O-N 3.15Å; P441-S444 WeakPolarHBondContact CD-OG 3.31Å; P441-S444 WeakPolarHBondContact O-CB 3.4Å; P441-S444 PolarHBondContact O-OG 3.44Å; P441-H446 WeakPolarHBondContact CD-CE1 3.49Å
442G98.2Very high97.7Very high19 Ų1964.1 Ų64.120%0.19632%0.322CS..THydrogen-bonded Turntrans-54.9139.2170.300000111.1S420 D423 S444S420-G442 CarbonylContact O-C 3.02Å; S420-G442 WeakPolarHBondContact O-CA 3.34Å; D423-G442 PolarHBondContact OD1-N 2.81Å; G442-S444 PolarHBondContact O-N 2.97Å
443Y98.4Very high97.3Very high119 Ų11972.2 Ų72.247%0.46735%0.349SS..THydrogen-bonded Turntrans52.851.2-179.4-56.1-60.1000113.6W313 M317 N418 R419 S420 P441W313-Y443 VanDerWaalsContact CE2-O 3.22Å; W313-Y443 WeakPolarHBondContact CZ2-O 3.43Å; W313-Y443 PolarHBondContact NE1-O 3.44Å; W313-Y443 VanDerWaalsContact NE1-O 3.14Å; M317-Y443 HydrophobicContact CE-CD1 4.03Å; M317-Y443 HydrophobicContact CE-CE1 4.34Å; M317-Y443 HydrophobicContact SD-CD1 3.94Å; N418-Y443 CarbonylContact O-C 3.42Å; N418-Y443 VanDerWaalsContact O-CA 3.24Å; N418-Y443 WeakPolarHBondContact O-CA 3.44Å; N418-Y443 PolarHBondContact O-N 3.45Å; R419-Y443 VanDerWaalsContact O-CE1 3.22Å; R419-Y443 WeakPolarHBondContact O-CE1 3.37Å; S420-Y443 PolarHBondContact O-N 2.89Å; P441-Y443 PolarHBondContact O-N 3.15Å
444S98.7Very high97.4Very high11 Ų1171.9 Ų71.98%0.07734%0.343CS..EExtended strand (participates in β ladder)trans-128.4160.3-178.771.10000112.8N418 P441 G442N418-S444 PolarHBondContact N-O 3.04Å; N418-S444 PolarHBondContact O-N 3.31Å; N418-S444 VanDerWaalsContact O-N 3.14Å; P441-S444 WeakPolarHBondContact CD-OG 3.31Å; P441-S444 WeakPolarHBondContact O-CB 3.4Å; P441-S444 PolarHBondContact O-OG 3.44Å; G442-S444 PolarHBondContact O-N 2.97Å
445I98.8Very high97.5Very high11 Ų1174.4 Ų74.46%0.05635%0.348CS..EExtended strand (participates in β ladder)trans-135.3127.3168.3-179.4169.7000109H378 F379 V415 V416 L417H378-I445 HydrophobicContact CB-CD1 3.65Å; H378-I445 HydrophobicContact CB-CG1 4.05Å; H378-I445 PolarHBondContact CE1-O 3.11Å; H378-I445 PolarHBondContact NE2-O 3.39Å; F379-I445 HydrophobicContact CE2-CD1 3.96Å; F379-I445 HydrophobicContact CZ-CD1 4.35Å; V415-I445 HydrophobicContact CG1-CD1 4.1Å; V415-I445 HydrophobicContact CG1-CG1 4.09Å; V416-I445 CarbonylContact O-C 3.52Å; V416-I445 WeakPolarHBondContact O-CA 3.12Å; L417-I445 HydrophobicContact CD1-CB 4.01Å
446H98.8Very high97.5Very high55 Ų5570.8 Ų70.826%0.25533%0.333SS..EExtended strand (participates in β ladder)trans-122.5143.7-179.3-67.4178.3000110.6V415 V416 I439 P441 Y448V415-H446 CarbonylContact C-O 3.57Å; V415-H446 WeakPolarHBondContact CA-O 3.27Å; V416-H446 PolarHBondContact N-O 3.49Å; V416-H446 PolarHBondContact O-N 3.02Å; I439-H446 PolarHBondContact O-CE1 2.9Å; I439-H446 VanDerWaalsContact O-CE1 3.31Å; P441-H446 WeakPolarHBondContact CD-CE1 3.49Å; H446-Y448 HydrophobicContact CB-CD2 4.32Å; H446-Y448 HydrophobicContact CB-CE2 3.56Å; H446-Y448 AromaticContact ND1-CZ 3.71Å; H446-Y448 PolarHBondContact ND1-OH 3.47Å
447T98.6Very high97.4Very high29 Ų2972.2 Ų72.218%0.17834%0.338CS..EExtended strand (participates in β ladder)trans-120.4117.9168.7-54.60000109.1H378 F382 V413 V414 V415H378-T447 WeakPolarHBondContact CB-OG1 3.49Å; H378-T447 PolarHBondContact ND1-OG1 3.21Å; H378-T447 PolarHBondContact O-OG1 2.59Å; F382-T447 HydrophobicContact CB-CG2 3.69Å; F382-T447 HydrophobicContact CD2-CG2 3.63Å; F382-T447 HydrophobicContact CE2-CG2 4.43Å; F382-T447 HydrophobicContact CG-CG2 3.8Å; V413-T447 HydrophobicContact CG2-CG2 3.6Å; V414-T447 CarbonylContact O-C 3.52Å; V414-T447 WeakPolarHBondContact O-CA 3.44Å; V415-T447 HydrophobicContact CG2-CG2 4Å
448Y98.6Very high97.4Very high34 Ų3466.2 Ų66.213%0.13331%0.31CS..EExtended strand (participates in β ladder)trans-101.7137179.6-57.9-85.5000109.8V413 V414 V416 I428 T438 H446V413-Y448 CarbonylContact C-O 3.46Å; V413-Y448 VanDerWaalsContact CA-O 3.31Å; V413-Y448 WeakPolarHBondContact CA-O 3.26Å; V414-Y448 PolarHBondContact N-O 2.81Å; V414-Y448 PolarHBondContact O-N 3.16Å; V416-Y448 HydrophobicContact CB-CE2 4.36Å; V416-Y448 HydrophobicContact CG2-CD2 4.3Å; V416-Y448 HydrophobicContact CG2-CE2 3.97Å; I428-Y448 HydrophobicContact CD1-CD2 3.78Å; I428-Y448 HydrophobicContact CD1-CE2 4.09Å; I428-Y448 HydrophobicContact CD1-CG 4.14Å; T438-Y448 HydrophobicContact CG2-CE1 3.98Å; T438-Y448 VanDerWaalsContact CG2-OH 3.26Å; T438-Y448 WeakPolarHBondContact CG2-OH 3.42Å; T438-Y448 PolarHBondContact OG1-OH 3.03Å; H446-Y448 HydrophobicContact CB-CD2 4.32Å; H446-Y448 HydrophobicContact CB-CE2 3.56Å; H446-Y448 AromaticContact ND1-CZ 3.71Å; H446-Y448 PolarHBondContact ND1-OH 3.47Å
449L98.1Very high97.4Very high85 Ų8567.7 Ų67.745%0.44531%0.313SS..EExtended strand (participates in β ladder)trans-134134.9-178.7-70.4163.1000109.6F382 A412 V413F382-L449 HydrophobicContact CB-CD1 4.41Å; F382-L449 HydrophobicContact CD1-CD1 3.51Å; F382-L449 HydrophobicContact CE1-CD1 4Å; F382-L449 HydrophobicContact CG-CD1 4.17Å; A412-L449 WeakPolarHBondContact O-CA 3.46Å; V413-L449 HydrophobicContact CB-CD2 3.57Å; V413-L449 HydrophobicContact CG2-CD2 3.59Å; V413-L449 HydrophobicContact CG2-CG 4.37Å
450W98.1Very high97.3Very high30 Ų3067.3 Ų67.311%0.11431%0.308CS..EExtended strand (participates in β ladder)trans-152.5155.5172.665.595.8000112.2F3 S411 A412 V414 I428 D430 L436F3-W450 HydrophobicContact CD2-CH2 4.47Å; F3-W450 HydrophobicContact CD2-CZ2 4.31Å; F3-W450 HydrophobicContact CE2-CH2 4.47Å; F3-W450 HydrophobicContact CE2-CZ2 4.33Å; S411-W450 WeakPolarHBondContact CB-O 3.16Å; A412-W450 HydrophobicContact CB-CD2 3.89Å; A412-W450 VanDerWaalsContact CB-CE2 3.41Å; A412-W450 HydrophobicContact CB-CE3 4.35Å; A412-W450 HydrophobicContact CB-CG 4.46Å; A412-W450 HydrophobicContact CB-CH2 3.98Å; A412-W450 HydrophobicContact CB-CZ2 3.46Å; A412-W450 VanDerWaalsContact CB-CZ2 3.46Å; A412-W450 HydrophobicContact CB-CZ3 4.39Å; A412-W450 PolarHBondContact N-O 2.82Å; A412-W450 PolarHBondContact O-N 3.05Å; V414-W450 HydrophobicContact CB-CH2 4.38Å; V414-W450 HydrophobicContact CB-CZ3 4.3Å; V414-W450 HydrophobicContact CG2-CH2 3.52Å; V414-W450 HydrophobicContact CG2-CZ3 3.9Å; I428-W450 HydrophobicContact CG2-CH2 3.97Å; D430-W450 HydrophobicContact CB-CZ2 3.96Å; D430-W450 PolarHBondContact OD2-NE1 3.47Å; L436-W450 HydrophobicContact CD2-CD2 4.44Å; L436-W450 HydrophobicContact CD2-CE3 3.99Å; L436-W450 HydrophobicContact CD2-CZ3 4.39Å
451R96.9Very high97.2Very high209 Ų20972.5 Ų72.579%0.78933%0.332SS*.  trans-80.1142.7170.2-65.6-172.5-179.2-152.30.1109.6
452R94.3Very high97.1Very high66 Ų6675 Ų7525%0.24934%0.337CS..  trans-97.6-12.3178.4-57.3-171.673.5-123.1-3113.6G410 A412 D430 A432 V433G410-R452 VanDerWaalsContact O-CD 3.24Å; G410-R452 WeakPolarHBondContact O-CD 3.36Å; G410-R452 WeakPolarHBondContact O-CG 3.21Å; A412-R452 HydrophobicContact CB-CG 4.19Å; D430-R452 IonicContact OD1-CZ 2.64Å; D430-R452 IonicContact OD1-NE 2.68Å; D430-R452 PolarHBondContact OD1-NE 2.91Å; D430-R452 IonicContact OD1-NH2 3.11Å; D430-R452 PolarHBondContact OD1-NH2 3.5Å; D430-R452 IonicContact OD2-CZ 3.81Å; D430-R452 IonicContact OD2-NE 2.71Å; D430-R452 PolarHBondContact OD2-NE 3.1Å; D430-R452 IonicContact OD2-NH2 3.61Å; A432-R452 VanDerWaalsContact CB-NH2 3.33Å; V433-R452 HydrophobicContact CG2-CB 4.43Å
453Q87.6Confident97Very high232 Ų23280.1 Ų80.1100%1.08435%0.35SS*.  trans-157.30176.460-172.73.300110.5

Retrieved 453 of 453 residues in 536.3 ms (Link to these results)