A0A068FR04_DANRE Loading...

Interferon-induced protein with tetratricopeptide repeats

AlphaFold DB , UniProt , Accession A0A068FR04, Species DANRE (Danio rerio, Zebrafish), Gene ifit14, Length 433 aa.

Structure Viewer
Loading PAE data...
(Predicted Aligned Error values between residue pairs)
Error loading PAE data: please refresh the page.

 

Download Structure   PDB   PAE   Table  
Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M60.3Low88.8Confident167 Ų16784.6 Ų84.682%0.82344%0.437SS*.  0-41.70-151.9177.6-98.500110S3 L4 L5M1-S3 VanDerWaalsContact C-N 3.34Å; M1-S3 PolarHBondContact O-N 3.24Å; M1-L4 PolarHBondContact O-N 3.28Å; M1-L5 PolarHBondContact O-N 3.44Å
2D73.3Confident89.4Confident92 Ų9279.2 Ų79.249%0.49241%0.409SS..Hα-helixtrans-60.6-36.8176.3-538.2000113.6L4 K6 L105D2-L4 VanDerWaalsContact C-N 3.32Å; D2-L4 PolarHBondContact O-N 3.15Å; D2-K6 VanDerWaalsContact O-CB 3.29Å; D2-K6 WeakPolarHBondContact O-CB 3.41Å; D2-K6 PolarHBondContact O-N 3.4Å; D2-L105 VanDerWaalsContact OD1-CD1 3.24Å; D2-L105 WeakPolarHBondContact OD1-CD1 3.24Å
3S82.2Confident90Very high100 Ų10077.5 Ų77.570%0.69940%0.398SS*.Hα-helixtrans-67.6-30.5178.366.50000113.5M1 G7M1-S3 VanDerWaalsContact C-N 3.34Å; M1-S3 PolarHBondContact O-N 3.24Å; S3-G7 PolarHBondContact O-N 3.29Å
4L90.9Very high90.6Very high111 Ų11172 Ų7258%0.58137%0.37SS*.Hα-helixtrans-77.7-47.3-179.5-170.5139.7000110.2M1 D2 K6 G7 E8M1-L4 PolarHBondContact O-N 3.28Å; D2-L4 VanDerWaalsContact C-N 3.32Å; D2-L4 PolarHBondContact O-N 3.15Å; L4-K6 VanDerWaalsContact C-N 3.33Å; L4-K6 PolarHBondContact O-N 3.12Å; L4-G7 PolarHBondContact O-N 3.42Å; L4-G7 VanDerWaalsContact O-N 3.12Å; L4-E8 PolarHBondContact O-N 2.98Å; L4-E8 VanDerWaalsContact O-N 3.15Å
5L93.4Very high91.1Very high0 Ų067.3 Ų67.30%035%0.346CS..Hα-helixtrans-59-44.3174.6179.359000111.4M1 G7 E8 L9 F100 L105 R109 L112M1-L5 PolarHBondContact O-N 3.44Å; L5-G7 VanDerWaalsContact C-N 3.29Å; L5-G7 PolarHBondContact O-N 3.28Å; L5-E8 WeakPolarHBondContact O-CB 3.29Å; L5-E8 PolarHBondContact O-N 2.94Å; L5-E8 VanDerWaalsContact O-N 3.08Å; L5-L9 HydrophobicContact CD1-CG 4.35Å; L5-L9 HydrophobicContact CG-CD1 4.21Å; L5-L9 HydrophobicContact CG-CG 4.43Å; L5-L9 WeakPolarHBondContact O-CG 3.45Å; L5-L9 PolarHBondContact O-N 2.96Å; L5-F100 HydrophobicContact CD2-CD2 3.9Å; L5-F100 HydrophobicContact CD2-CE2 4.39Å; L5-F100 HydrophobicContact CG-CD2 4.16Å; L5-F100 HydrophobicContact CG-CE2 4.47Å; L5-L105 HydrophobicContact CD2-CB 4.42Å; L5-L105 HydrophobicContact CD2-CD2 4.24Å; L5-R109 HydrophobicContact CD1-CG 4.15Å; L5-R109 HydrophobicContact CD2-CG 4.25Å; L5-L112 HydrophobicContact CD1-CD2 4.07Å
6K94.4Very high91.4Very high93 Ų9364.8 Ų64.840%0.40433%0.331SS..Hα-helixtrans-57.2-42.4175.6-172.8178.4175.6-172.10112.2D2 L4 E8 L9 E10 F100D2-K6 VanDerWaalsContact O-CB 3.29Å; D2-K6 WeakPolarHBondContact O-CB 3.41Å; D2-K6 PolarHBondContact O-N 3.4Å; L4-K6 VanDerWaalsContact C-N 3.33Å; L4-K6 PolarHBondContact O-N 3.12Å; K6-E8 VanDerWaalsContact C-N 3.27Å; K6-E8 PolarHBondContact O-N 3.38Å; K6-L9 PolarHBondContact O-N 3.38Å; K6-E10 WeakPolarHBondContact CE-OE1 3.34Å; K6-E10 IonicContact NZ-OE1 3.43Å; K6-E10 WeakPolarHBondContact O-CG 3.33Å; K6-E10 PolarHBondContact O-N 3.27Å; K6-F100 HydrophobicContact CB-CE1 4.41Å; K6-F100 HydrophobicContact CB-CE2 4.19Å; K6-F100 HydrophobicContact CB-CZ 3.75Å; K6-F100 HydrophobicContact CD-CE1 4.43Å; K6-F100 HydrophobicContact CD-CZ 4.26Å; K6-F100 HydrophobicContact CG-CE1 4.28Å; K6-F100 HydrophobicContact CG-CZ 4.08Å
7G96.1Very high91.8Very high25 Ų2563.5 Ų63.526%0.25833%0.327SS..Hα-helixtrans-67-24.5177.700000114.1S3 L4 L5 K11S3-G7 PolarHBondContact O-N 3.29Å; L4-G7 PolarHBondContact O-N 3.42Å; L4-G7 VanDerWaalsContact O-N 3.12Å; L5-G7 VanDerWaalsContact C-N 3.29Å; L5-G7 PolarHBondContact O-N 3.28Å; G7-K11 WeakPolarHBondContact O-CE 3.34Å; G7-K11 WeakPolarHBondContact O-CG 3.48Å
8E96.3Very high92.1Very high63 Ų6360.3 Ų60.329%0.29431%0.31SS..Hα-helixtrans-76.2-45.6170.6-68170.3152.600110.8L4 L5 K6 E10 K11 L112L4-E8 PolarHBondContact O-N 2.98Å; L4-E8 VanDerWaalsContact O-N 3.15Å; L5-E8 WeakPolarHBondContact O-CB 3.29Å; L5-E8 PolarHBondContact O-N 2.94Å; L5-E8 VanDerWaalsContact O-N 3.08Å; K6-E8 VanDerWaalsContact C-N 3.27Å; K6-E8 PolarHBondContact O-N 3.38Å; E8-E10 VanDerWaalsContact C-N 3.28Å; E8-E10 PolarHBondContact O-N 3.08Å; E8-K11 WeakPolarHBondContact O-CB 3.46Å; E8-K11 PolarHBondContact O-N 3.33Å; E8-L112 HydrophobicContact CB-CD2 4.03Å
9L97.3Very high92.2Very high0 Ų063.4 Ų63.40%033%0.328CS..Hα-helixtrans-60.1-35.8177.5-66176.3000112.9L5 K6 K11 L12 A96 W97 F100L5-L9 HydrophobicContact CD1-CG 4.35Å; L5-L9 HydrophobicContact CG-CD1 4.21Å; L5-L9 HydrophobicContact CG-CG 4.43Å; L5-L9 WeakPolarHBondContact O-CG 3.45Å; L5-L9 PolarHBondContact O-N 2.96Å; K6-L9 PolarHBondContact O-N 3.38Å; L9-K11 PolarHBondContact O-N 2.96Å; L9-L12 HydrophobicContact CD2-CD1 3.77Å; L9-L12 WeakPolarHBondContact O-CB 3.4Å; L9-L12 WeakPolarHBondContact O-CG 3.45Å; L9-L12 PolarHBondContact O-N 3.26Å; L9-L12 VanDerWaalsContact O-N 3.15Å; L9-A96 HydrophobicContact CD2-CB 3.64Å; L9-W97 HydrophobicContact CB-CD2 4.1Å; L9-W97 HydrophobicContact CB-CH2 4.22Å; L9-W97 HydrophobicContact CB-CZ2 3.69Å; L9-W97 HydrophobicContact CD1-CD2 4.44Å; L9-W97 HydrophobicContact CD1-CE3 4.43Å; L9-W97 PolarHBondContact O-NE1 2.93Å; L9-F100 HydrophobicContact CD1-CB 3.5Å; L9-F100 VanDerWaalsContact CD1-CB 3.5Å; L9-F100 HydrophobicContact CD1-CD1 4.06Å; L9-F100 HydrophobicContact CD1-CD2 3.69Å; L9-F100 HydrophobicContact CD1-CE2 4.45Å; L9-F100 HydrophobicContact CD1-CG 3.46Å; L9-F100 VanDerWaalsContact CD1-CG 3.46Å
10E96.9Very high92.2Very high111 Ų11160.7 Ų60.752%0.51931%0.314SS..THydrogen-bonded Turntrans-64.3-19.3176.5-77173.3175.200113.8K6 E8 W97K6-E10 WeakPolarHBondContact CE-OE1 3.34Å; K6-E10 IonicContact NZ-OE1 3.43Å; K6-E10 WeakPolarHBondContact O-CG 3.33Å; K6-E10 PolarHBondContact O-N 3.27Å; E8-E10 VanDerWaalsContact C-N 3.28Å; E8-E10 PolarHBondContact O-N 3.08Å; E10-W97 HydrophobicContact CG-CH2 4.01Å; E10-W97 HydrophobicContact CG-CZ2 4.02Å
11K95.8Very high92Very high169 Ų16958.8 Ų58.874%0.73531%0.309SS*.THydrogen-bonded Turntrans-87.9-13.1176.5-60.8169.6-171.9170.20113.1G7 E8 L9G7-K11 WeakPolarHBondContact O-CE 3.34Å; G7-K11 WeakPolarHBondContact O-CG 3.48Å; E8-K11 WeakPolarHBondContact O-CB 3.46Å; E8-K11 PolarHBondContact O-N 3.33Å; L9-K11 PolarHBondContact O-N 2.96Å
12L96.4Very high93.4Very high19 Ų1956.3 Ų56.310%0.09930%0.295CS..SBendtrans-70.9153.6-176.9-58.7-174.1000111.3L9 T17 A93 A96 L112 L115L9-L12 HydrophobicContact CD2-CD1 3.77Å; L9-L12 WeakPolarHBondContact O-CB 3.4Å; L9-L12 WeakPolarHBondContact O-CG 3.45Å; L9-L12 PolarHBondContact O-N 3.26Å; L9-L12 VanDerWaalsContact O-N 3.15Å; L12-T17 VanDerWaalsContact O-CB 3.26Å; L12-T17 WeakPolarHBondContact O-CB 3.5Å; L12-T17 WeakPolarHBondContact O-CG2 3.43Å; L12-T17 PolarHBondContact O-OG1 3.41Å; L12-A93 HydrophobicContact CB-CB 4.08Å; L12-A93 HydrophobicContact CD1-CB 3.94Å; L12-A96 HydrophobicContact CD1-CB 4.47Å; L12-L112 HydrophobicContact CD1-CD1 4.05Å; L12-L112 HydrophobicContact CD2-CD1 3.85Å; L12-L112 HydrophobicContact CG-CD1 4.41Å; L12-L115 HydrophobicContact CD1-CD2 4.01Å; L12-L115 HydrophobicContact CD2-CD2 3.59Å; L12-L115 HydrophobicContact CG-CD2 4.32Å
13E96.6Very high94.4Very high58 Ų5855.9 Ų55.927%0.27129%0.287SS..  trans-100.793.6176.9-77.2-77.3179.700110.2W18 L130 V134 K138E13-W18 PolarHBondContact OE2-NE1 2.92Å; E13-L130 HydrophobicContact CG-CD2 3.63Å; E13-V134 HydrophobicContact CB-CG1 3.65Å; E13-V134 HydrophobicContact CG-CG1 4.46Å; E13-K138 IonicContact OE1-NZ 2.61Å; E13-K138 PolarHBondContact OE1-NZ 2.95Å; E13-K138 IonicContact OE2-NZ 2.99Å; E13-K138 PolarHBondContact OE2-NZ 3.2Å
14C97.8Very high95Very high0 Ų056.2 Ų56.20%028%0.278CS..SBendtrans-155-179.6-178.872.50000112.7F16 T17 W18 V90 A93 N94C14-F16 PolarHBondContact O-N 3.06Å; C14-F16 VanDerWaalsContact O-N 3.13Å; C14-T17 PolarHBondContact N-OG1 2.99Å; C14-T17 VanDerWaalsContact N-OG1 3.12Å; C14-T17 PolarHBondContact O-N 3.32Å; C14-T17 PolarHBondContact O-OG1 3.34Å; C14-T17 VanDerWaalsContact O-OG1 3.06Å; C14-W18 VanDerWaalsContact O-CD2 3.3Å; C14-W18 PolarHBondContact O-N 3.18Å; C14-W18 VanDerWaalsContact O-N 3.1Å; C14-W18 PolarHBondContact O-NE1 3.31Å; C14-V90 HydrophobicContact CB-CG1 4.29Å; C14-A93 HydrophobicContact CB-CB 3.59Å; C14-N94 WeakPolarHBondContact CB-OD1 3.49Å
15H98Very high95.1Very high2 Ų251.5 Ų51.51%0.00925%0.253CS..THydrogen-bonded Turntrans-62.1-28.4-173.5-68.373.1000113.3T17 W18 L20 F54 N94 E137 T141H15-T17 VanDerWaalsContact C-N 3.32Å; H15-W18 AromaticContact CE1-CZ3 3.7Å; H15-W18 AromaticContact ND1-CZ3 3.9Å; H15-W18 AromaticContact NE2-CZ3 3.85Å; H15-L20 HydrophobicContact CB-CD1 4.06Å; H15-F54 HydrophobicContact CB-CB 3.58Å; H15-F54 HydrophobicContact CB-CD1 4.28Å; H15-F54 HydrophobicContact CB-CD2 3.57Å; H15-F54 HydrophobicContact CB-CE2 4.35Å; H15-F54 HydrophobicContact CB-CG 3.53Å; H15-F54 WeakPolarHBondContact O-CE2 3.4Å; H15-N94 PolarHBondContact N-OD1 2.99Å; H15-N94 VanDerWaalsContact N-OD1 3.14Å; H15-N94 PolarHBondContact ND1-ND2 2.89Å; H15-N94 VanDerWaalsContact ND1-ND2 3.13Å; H15-E137 IonicContact CE1-OE1 3.56Å; H15-E137 PolarHBondContact CE1-OE1 3.4Å; H15-E137 VanDerWaalsContact CE1-OE1 3.31Å; H15-T141 PolarHBondContact NE2-OG1 3.47Å
16F97.3Very high95.1Very high26 Ų2652.8 Ų52.811%0.11426%0.259CS..THydrogen-bonded Turntrans-75.3-18.1178.1-63.8-80.1000113.8C14 F54 K57 N94 W97 V98 Y101C14-F16 PolarHBondContact O-N 3.06Å; C14-F16 VanDerWaalsContact O-N 3.13Å; F16-F54 AromaticContact CD1-CD2 3.88Å; F16-F54 HydrophobicContact CD1-CD2 3.88Å; F16-F54 HydrophobicContact CD1-CE2 4.1Å; F16-F54 HydrophobicContact CD2-CD2 4.49Å; F16-F54 AromaticContact CE1-CD2 3.82Å; F16-F54 HydrophobicContact CE1-CD2 3.82Å; F16-F54 HydrophobicContact CE1-CE2 4.32Å; F16-F54 HydrophobicContact CE2-CD2 4.43Å; F16-F54 HydrophobicContact CG-CD2 4.24Å; F16-F54 HydrophobicContact CZ-CD2 4.1Å; F16-K57 HydrophobicContact CE1-CB 4.25Å; F16-K57 HydrophobicContact CE1-CG 3.85Å; F16-K57 HydrophobicContact CZ-CB 4.02Å; F16-K57 HydrophobicContact CZ-CG 3.89Å; F16-N94 WeakPolarHBondContact CD2-OD1 3.43Å; F16-N94 HydrophobicContact CE2-CB 4.2Å; F16-W97 HydrophobicContact CB-CB 4.28Å; F16-W97 HydrophobicContact CB-CD2 3.92Å; F16-W97 HydrophobicContact CB-CG 3.77Å; F16-W97 HydrophobicContact CD2-CB 3.49Å; F16-W97 VanDerWaalsContact CD2-CB 3.49Å; F16-W97 AromaticContact CD2-CG 3.88Å; F16-W97 HydrophobicContact CD2-CG 3.88Å; F16-W97 HydrophobicContact CE2-CB 3.92Å; F16-W97 HydrophobicContact CG-CB 3.88Å; F16-W97 HydrophobicContact CG-CD2 4.35Å; F16-W97 AromaticContact CG-CG 3.92Å; F16-W97 HydrophobicContact CG-CG 3.92Å; F16-V98 HydrophobicContact CE2-CG2 3.94Å; F16-V98 HydrophobicContact CZ-CG2 3.74Å; F16-Y101 AromaticContact CD1-CE2 3.75Å; F16-Y101 HydrophobicContact CD1-CE2 3.75Å; F16-Y101 HydrophobicContact CE1-CD2 4.4Å; F16-Y101 AromaticContact CE1-CE2 3.87Å; F16-Y101 HydrophobicContact CE1-CE2 3.87Å; F16-Y101 HydrophobicContact CG-CE2 4.42Å
17T97.3Very high95.1Very high43 Ų4348.4 Ų48.426%0.26424%0.24SC..THydrogen-bonded Turntrans-112.3-5.4-178.757.80000113.4L12 C14 H15 D19 W97L12-T17 VanDerWaalsContact O-CB 3.26Å; L12-T17 WeakPolarHBondContact O-CB 3.5Å; L12-T17 WeakPolarHBondContact O-CG2 3.43Å; L12-T17 PolarHBondContact O-OG1 3.41Å; C14-T17 PolarHBondContact N-OG1 2.99Å; C14-T17 VanDerWaalsContact N-OG1 3.12Å; C14-T17 PolarHBondContact O-N 3.32Å; C14-T17 PolarHBondContact O-OG1 3.34Å; C14-T17 VanDerWaalsContact O-OG1 3.06Å; H15-T17 VanDerWaalsContact C-N 3.32Å; T17-D19 VanDerWaalsContact C-N 3.26Å; T17-D19 PolarHBondContact O-N 3.38Å; T17-W97 HydrophobicContact CG2-CZ2 4.04Å
18W97Very high95Very high6 Ų651 Ų512%0.02325%0.245CC..THydrogen-bonded Turntrans-82.58.9-179.9-66.5-9.7000115.6E13 C14 H15 L20 V90 V134 E137 K138 T141E13-W18 PolarHBondContact OE2-NE1 2.92Å; C14-W18 VanDerWaalsContact O-CD2 3.3Å; C14-W18 PolarHBondContact O-N 3.18Å; C14-W18 VanDerWaalsContact O-N 3.1Å; C14-W18 PolarHBondContact O-NE1 3.31Å; H15-W18 AromaticContact CE1-CZ3 3.7Å; H15-W18 AromaticContact ND1-CZ3 3.9Å; H15-W18 AromaticContact NE2-CZ3 3.85Å; W18-L20 VanDerWaalsContact C-N 3.29Å; W18-L20 HydrophobicContact CB-CD2 3.85Å; W18-L20 HydrophobicContact CB-CG 4.02Å; W18-L20 PolarHBondContact O-N 3.27Å; W18-V90 HydrophobicContact CH2-CG1 3.83Å; W18-V90 HydrophobicContact CH2-CG2 3.93Å; W18-V90 HydrophobicContact CZ2-CG1 4.26Å; W18-V90 HydrophobicContact CZ2-CG2 3.97Å; W18-V134 HydrophobicContact CZ2-CG1 4.47Å; W18-E137 HydrophobicContact CH2-CB 4.23Å; W18-E137 HydrophobicContact CH2-CG 3.98Å; W18-E137 HydrophobicContact CZ3-CG 4.4Å; W18-K138 HydrophobicContact CD2-CB 4.2Å; W18-K138 HydrophobicContact CD2-CD 4.05Å; W18-K138 HydrophobicContact CD2-CG 3.7Å; W18-K138 HydrophobicContact CE3-CB 4.35Å; W18-K138 HydrophobicContact CE3-CG 4.12Å; W18-K138 HydrophobicContact CG-CD 4.1Å; W18-K138 HydrophobicContact CG-CG 4.09Å; W18-K138 VanDerWaalsContact CH2-CA 3.49Å; W18-K138 HydrophobicContact CH2-CB 3.78Å; W18-K138 HydrophobicContact CH2-CG 4.37Å; W18-K138 HydrophobicContact CZ2-CB 3.61Å; W18-K138 HydrophobicContact CZ2-CD 4.19Å; W18-K138 HydrophobicContact CZ2-CG 3.98Å; W18-K138 HydrophobicContact CZ3-CB 4.16Å; W18-K138 HydrophobicContact CZ3-CG 4.44Å; W18-T141 HydrophobicContact CE3-CG2 3.91Å; W18-T141 HydrophobicContact CZ3-CG2 4.07Å
19D93.9Very high94.9Very high120 Ų12048.6 Ų48.664%0.64224%0.238SC*.THydrogen-bonded Turntrans52.646.7178.4175.948.9000111.8T17 G21 K149T17-D19 VanDerWaalsContact C-N 3.26Å; T17-D19 PolarHBondContact O-N 3.38Å; D19-G21 PolarHBondContact O-N 2.76Å; D19-K149 WeakPolarHBondContact O-CE 3.41Å; D19-K149 PolarHBondContact O-NZ 2.93Å; D19-K149 IonicContact OD2-NZ 2.76Å; D19-K149 PolarHBondContact OD2-NZ 3.47Å
20L93.1Very high94.7Very high9 Ų949.4 Ų49.45%0.04724%0.242CC..  trans-72.1-17.2-175.6-58.5-179.5000112.9H15 W18 F54 T141 L142 F145H15-L20 HydrophobicContact CB-CD1 4.06Å; W18-L20 VanDerWaalsContact C-N 3.29Å; W18-L20 HydrophobicContact CB-CD2 3.85Å; W18-L20 HydrophobicContact CB-CG 4.02Å; W18-L20 PolarHBondContact O-N 3.27Å; L20-F54 HydrophobicContact CB-CE1 4.18Å; L20-F54 HydrophobicContact CB-CZ 4.07Å; L20-F54 HydrophobicContact CD1-CD1 4.11Å; L20-F54 HydrophobicContact CD1-CE1 3.79Å; L20-F54 HydrophobicContact CD1-CZ 4.06Å; L20-T141 HydrophobicContact CD1-CG2 3.59Å; L20-T141 HydrophobicContact CD2-CG2 3.77Å; L20-T141 HydrophobicContact CG-CG2 4.35Å; L20-L142 HydrophobicContact CD2-CD2 3.95Å; L20-F145 HydrophobicContact CB-CE1 4.11Å; L20-F145 HydrophobicContact CB-CE2 4.22Å; L20-F145 HydrophobicContact CB-CZ 3.82Å; L20-F145 HydrophobicContact CD1-CE2 4.12Å; L20-F145 HydrophobicContact CD1-CZ 4.12Å; L20-F145 HydrophobicContact CD2-CD2 4.22Å; L20-F145 HydrophobicContact CD2-CE2 3.93Å; L20-F145 HydrophobicContact CD2-CZ 4.39Å; L20-F145 HydrophobicContact CG-CE2 4.31Å; L20-F145 HydrophobicContact CG-CZ 4.32Å
21G88.4Confident94.6Very high20 Ų2046.9 Ų46.921%0.20623%0.229CC..  trans78147-166.300000111.6D19D19-G21 PolarHBondContact O-N 2.76Å
22Q90Very high94.3Very high115 Ų11541.8 Ų41.854%0.53721%0.205SC..  trans-119.250.3-179.3-65.6-178.15.400110.9Q24 L27 F54Q22-Q24 PolarHBondContact O-N 3.12Å; Q22-L27 HydrophobicContact CB-CD1 4.48Å; Q22-F54 HydrophobicContact CG-CZ 4.32Å
23Y93.9Very high93.9Very high83 Ų8346.3 Ų46.333%0.32522%0.224SC..  trans-82.3113.9-179.6-56.7-78.4000110N25 E26 L27 L357 P358 P359Y23-N25 VanDerWaalsContact C-N 3.3Å; Y23-N25 PolarHBondContact O-N 3.23Å; Y23-E26 PolarHBondContact O-N 2.96Å; Y23-L27 WeakPolarHBondContact O-CG 3.35Å; Y23-L27 PolarHBondContact O-N 2.66Å; Y23-L357 WeakPolarHBondContact CD1-O 3.41Å; Y23-P358 HydrophobicContact CD1-CB 4.25Å; Y23-P358 HydrophobicContact CD2-CB 3.49Å; Y23-P358 VanDerWaalsContact CD2-CB 3.49Å; Y23-P358 HydrophobicContact CE2-CB 3.91Å; Y23-P358 HydrophobicContact CG-CB 3.69Å; Y23-P359 VanDerWaalsContact OH-CD 3.25Å; Y23-P359 WeakPolarHBondContact OH-CD 3.38Å
24Q93.3Very high93.6Very high108 Ų10844.3 Ų44.351%0.50522%0.215SC..Hα-helixtrans-52.2-45.7-173-70.3-176.4-13.500112.8Q22 E26 L27 Q28Q22-Q24 PolarHBondContact O-N 3.12Å; Q24-E26 PolarHBondContact O-N 2.97Å; Q24-L27 PolarHBondContact O-N 3.43Å; Q24-Q28 WeakPolarHBondContact O-CB 3.24Å; Q24-Q28 WeakPolarHBondContact O-CG 3.43Å; Q24-Q28 PolarHBondContact O-N 3.42Å
25N93Very high93Very high12 Ų1248.8 Ų48.86%0.06424%0.239CC..Hα-helixtrans-61-43.2179.7175.3-90.7000112.7Y23 G29 D322 T356 L357Y23-N25 VanDerWaalsContact C-N 3.3Å; Y23-N25 PolarHBondContact O-N 3.23Å; N25-G29 PolarHBondContact O-N 3.49Å; N25-G29 VanDerWaalsContact O-N 3.08Å; N25-D322 WeakPolarHBondContact ND2-CA 3.32Å; N25-D322 WeakPolarHBondContact ND2-CB 3.46Å; N25-D322 PolarHBondContact ND2-O 2.93Å; N25-D322 PolarHBondContact OD1-O 2.85Å; N25-D322 VanDerWaalsContact OD1-O 3.09Å; N25-T356 PolarHBondContact N-O 2.97Å; N25-L357 HydrophobicContact CB-CD2 3.63Å
26E93.6Very high92.1Very high27 Ų2755.4 Ų55.413%0.12627%0.269CS..Hα-helixtrans-67.7-45.4179.5-175170.3-135.400110.9Y23 Q24 G29 M30 P358 H360Y23-E26 PolarHBondContact O-N 2.96Å; Q24-E26 PolarHBondContact O-N 2.97Å; E26-G29 PolarHBondContact O-N 3.06Å; E26-M30 HydrophobicContact CG-SD 4.35Å; E26-M30 WeakPolarHBondContact O-CG 3.35Å; E26-M30 PolarHBondContact O-N 3.24Å; E26-P358 HydrophobicContact CB-CG 4.12Å; E26-H360 IonicContact OE1-CE1 2.8Å; E26-H360 PolarHBondContact OE1-CE1 3.23Å; E26-H360 VanDerWaalsContact OE1-CE1 3.3Å; E26-H360 IonicContact OE1-NE2 2.88Å
27L95.3Very high91.3Very high1 Ų157.2 Ų57.21%0.00528%0.283CS..Hα-helixtrans-67-41.5-179-65.1-179.2000112.5Q22 Y23 Q24 G29 M30 K31 F54 I55 S58 L59Q22-L27 HydrophobicContact CB-CD1 4.48Å; Y23-L27 WeakPolarHBondContact O-CG 3.35Å; Y23-L27 PolarHBondContact O-N 2.66Å; Q24-L27 PolarHBondContact O-N 3.43Å; L27-G29 VanDerWaalsContact C-N 3.33Å; L27-G29 PolarHBondContact O-N 3.04Å; L27-M30 PolarHBondContact O-N 3.43Å; L27-K31 PolarHBondContact O-N 3.32Å; L27-F54 HydrophobicContact CD2-CE1 4.12Å; L27-I55 HydrophobicContact CB-CG2 4.31Å; L27-I55 HydrophobicContact CD2-CG1 4.09Å; L27-S58 VanDerWaalsContact CD1-CB 3.45Å; L27-L59 HydrophobicContact CB-CD1 4.4Å; L27-L59 HydrophobicContact CB-CD2 4.06Å; L27-L59 HydrophobicContact CB-CG 4.24Å
28Q94.8Very high90.5Very high78 Ų7858.2 Ų58.236%0.36429%0.286SS..Hα-helixtrans-62.1-42.6173.1-72.7172.9-11.100111.2Q24 M30 K31 R32 L59 D322Q24-Q28 WeakPolarHBondContact O-CB 3.24Å; Q24-Q28 WeakPolarHBondContact O-CG 3.43Å; Q24-Q28 PolarHBondContact O-N 3.42Å; Q28-M30 VanDerWaalsContact C-N 3.3Å; Q28-M30 PolarHBondContact O-N 2.73Å; Q28-K31 PolarHBondContact O-N 3.05Å; Q28-R32 PolarHBondContact O-N 3.04Å; Q28-L59 HydrophobicContact CG-CD1 4.14Å; Q28-L59 HydrophobicContact CG-CD2 3.87Å; Q28-D322 VanDerWaalsContact C-OD2 3.24Å; Q28-D322 WeakPolarHBondContact CB-OD2 3.2Å
29G92.6Very high89.5Confident13 Ų1359.2 Ų59.213%0.13429%0.293CS..Hα-helixtrans-65.2-31.8175.700000113.2N25 E26 L27 K33 D322N25-G29 PolarHBondContact O-N 3.49Å; N25-G29 VanDerWaalsContact O-N 3.08Å; E26-G29 PolarHBondContact O-N 3.06Å; L27-G29 VanDerWaalsContact C-N 3.33Å; L27-G29 PolarHBondContact O-N 3.04Å; G29-K33 WeakPolarHBondContact O-CD 3.39Å; G29-K33 VanDerWaalsContact O-CG 3.31Å; G29-K33 WeakPolarHBondContact O-CG 3.28Å; G29-K33 PolarHBondContact O-N 3.15Å; G29-D322 PolarHBondContact N-OD2 3.2Å
30M93.3Very high88.4Confident17 Ų1762 Ų628%0.08430%0.303CS..Hα-helixtrans-71.5-48172.1-73.5178.769.700111.5E26 L27 Q28 R32 K33 M34 L51 I55 K144 F145E26-M30 HydrophobicContact CG-SD 4.35Å; E26-M30 WeakPolarHBondContact O-CG 3.35Å; E26-M30 PolarHBondContact O-N 3.24Å; L27-M30 PolarHBondContact O-N 3.43Å; Q28-M30 VanDerWaalsContact C-N 3.3Å; Q28-M30 PolarHBondContact O-N 2.73Å; M30-R32 PolarHBondContact O-N 2.96Å; M30-K33 WeakPolarHBondContact O-CB 3.18Å; M30-K33 PolarHBondContact O-N 2.95Å; M30-K33 VanDerWaalsContact O-N 3.11Å; M30-M34 WeakPolarHBondContact O-CG 3.49Å; M30-M34 PolarHBondContact O-N 3.15Å; M30-L51 HydrophobicContact CE-CD1 4.35Å; M30-L51 HydrophobicContact CE-CD2 4.01Å; M30-I55 HydrophobicContact CB-CD1 3.94Å; M30-I55 HydrophobicContact CE-CD1 4.26Å; M30-K144 HydrophobicContact CE-CB 4.07Å; M30-K144 HydrophobicContact CE-CD 4.44Å; M30-F145 HydrophobicContact CE-CE1 4.3Å; M30-F145 HydrophobicContact CE-CE2 3.96Å; M30-F145 HydrophobicContact CE-CZ 3.74Å; M30-F145 HydrophobicContact SD-CD1 4.37Å; M30-F145 HydrophobicContact SD-CE1 3.75Å; M30-F145 HydrophobicContact SD-CE2 4.46Å; M30-F145 HydrophobicContact SD-CZ 3.8Å
31K94.3Very high87.4Confident59 Ų5970 Ų7026%0.25734%0.337SS..Hα-helixtrans-53-52.3177-172.2-178.8175.1-176.60111.5L27 Q28 K33 M34 D35 L52 I55 L59L27-K31 PolarHBondContact O-N 3.32Å; Q28-K31 PolarHBondContact O-N 3.05Å; K31-K33 VanDerWaalsContact C-N 3.27Å; K31-K33 PolarHBondContact O-N 3.49Å; K31-M34 CarbonylContact O-C 3.51Å; K31-M34 WeakPolarHBondContact O-CA 3.42Å; K31-M34 WeakPolarHBondContact O-CB 3.34Å; K31-M34 PolarHBondContact O-N 3.04Å; K31-D35 VanDerWaalsContact O-CG 3.32Å; K31-D35 PolarHBondContact O-N 3.14Å; K31-L52 HydrophobicContact CG-CD1 4.44Å; K31-I55 HydrophobicContact CB-CG2 3.97Å; K31-L59 HydrophobicContact CD-CD1 4.24Å
32R91.5Very high86.8Confident62 Ų6271.3 Ų71.323%0.23434%0.339CS..Hα-helixtrans-60.8-33.5179.3-73.1-158.5-59-79.6-13.7113.8Q28 M30 M34 H36 D322Q28-R32 PolarHBondContact O-N 3.04Å; M30-R32 PolarHBondContact O-N 2.96Å; R32-M34 VanDerWaalsContact C-N 3.31Å; R32-H36 PolarHBondContact O-CD2 3.45Å; R32-D322 IonicContact CZ-OD1 2.77Å; R32-D322 IonicContact CZ-OD2 3.96Å; R32-D322 VanDerWaalsContact NH1-CG 3.29Å; R32-D322 IonicContact NH1-OD1 3.74Å; R32-D322 PolarHBondContact NH1-OD1 2.92Å; R32-D322 VanDerWaalsContact NH1-OD1 3.15Å; R32-D322 IonicContact NH1-OD2 3.31Å; R32-D322 PolarHBondContact NH1-OD2 3.36Å; R32-D322 VanDerWaalsContact NH2-CB 3.32Å; R32-D322 IonicContact NH2-OD1 3.92Å; R32-D322 PolarHBondContact NH2-OD1 3.48Å; R32-D322 IonicContact NH2-OD2 3.96Å; R32-D322 PolarHBondContact NH2-OD2 3.27Å
33K87.4Confident86Confident113 Ų11370.3 Ų70.349%0.49135%0.345SS..Hα-helixtrans-68-35.7173.7-71.6168-170.3162.80111.3G29 M30 K31 V37G29-K33 WeakPolarHBondContact O-CD 3.39Å; G29-K33 VanDerWaalsContact O-CG 3.31Å; G29-K33 WeakPolarHBondContact O-CG 3.28Å; G29-K33 PolarHBondContact O-N 3.15Å; M30-K33 WeakPolarHBondContact O-CB 3.18Å; M30-K33 PolarHBondContact O-N 2.95Å; M30-K33 VanDerWaalsContact O-N 3.11Å; K31-K33 VanDerWaalsContact C-N 3.27Å; K31-K33 PolarHBondContact O-N 3.49Å; K33-V37 WeakPolarHBondContact O-CG2 3.5Å
34M89.8Confident85.4Confident17 Ų1767 Ų678%0.08433%0.334CS..Hα-helixtrans-71.7-37179.1-69.4176.269.500111.7M30 K31 R32 H36 V37 Y48 L51 L52 I55M30-M34 WeakPolarHBondContact O-CG 3.49Å; M30-M34 PolarHBondContact O-N 3.15Å; K31-M34 CarbonylContact O-C 3.51Å; K31-M34 WeakPolarHBondContact O-CA 3.42Å; K31-M34 WeakPolarHBondContact O-CB 3.34Å; K31-M34 PolarHBondContact O-N 3.04Å; R32-M34 VanDerWaalsContact C-N 3.31Å; M34-H36 PolarHBondContact O-N 3.25Å; M34-V37 WeakPolarHBondContact O-CB 3.38Å; M34-V37 PolarHBondContact O-N 3.06Å; M34-Y48 HydrophobicContact CB-CE2 3.71Å; M34-Y48 HydrophobicContact CE-CD2 3.51Å; M34-Y48 HydrophobicContact CE-CE1 4.46Å; M34-Y48 HydrophobicContact CE-CE2 3.47Å; M34-Y48 VanDerWaalsContact CE-CE2 3.47Å; M34-Y48 HydrophobicContact CE-CG 4.06Å; M34-Y48 VanDerWaalsContact CE-O 3.31Å; M34-Y48 WeakPolarHBondContact CE-O 3.38Å; M34-Y48 HydrophobicContact CG-CE2 4.02Å; M34-Y48 PolarHBondContact O-OH 2.92Å; M34-Y48 VanDerWaalsContact O-OH 3.09Å; M34-L51 HydrophobicContact CE-CB 4.45Å; M34-L51 HydrophobicContact CE-CD2 4.45Å; M34-L51 HydrophobicContact CE-CG 4.43Å; M34-L51 HydrophobicContact SD-CD2 4.19Å; M34-L51 HydrophobicContact SD-CG 4.36Å; M34-L52 HydrophobicContact CE-CB 3.81Å; M34-L52 HydrophobicContact CE-CD1 4.42Å; M34-I55 HydrophobicContact SD-CD1 3.69Å
35D86.1Confident85.1Confident94 Ų9463 Ų6350%0.50332%0.317SS..Hα-helixtrans-58.2-22.3177.9-62.8-25.4000113.8K31K31-D35 VanDerWaalsContact O-CG 3.32Å; K31-D35 PolarHBondContact O-N 3.14Å
36H78.8Confident85Confident140 Ų14062.6 Ų62.665%0.64832%0.315SS*.THydrogen-bonded Turntrans-95.71.2177.6-61.4-51.4000114R32 M34R32-H36 PolarHBondContact O-CD2 3.45Å; M34-H36 PolarHBondContact O-N 3.25Å
37V81Confident85Confident65 Ų6562.2 Ų62.239%0.39431%0.313SS..SBendtrans-99.6128.4178.1-177.60000108.7K33 M34 P39 I42 Y48K33-V37 WeakPolarHBondContact O-CG2 3.5Å; M34-V37 WeakPolarHBondContact O-CB 3.38Å; M34-V37 PolarHBondContact O-N 3.06Å; V37-P39 WeakPolarHBondContact O-CD 3.32Å; V37-I42 HydrophobicContact CG1-CD1 3.58Å; V37-I42 HydrophobicContact CG1-CG1 3.72Å; V37-Y48 HydrophobicContact CB-CE2 4.48Å
38D79.1Confident84.9Confident63 Ų6363.4 Ų63.434%0.33732%0.318SS..  trans-73.8112.1168.3179-2.8000109.4Q40 K41D38-Q40 PolarHBondContact O-N 2.92Å; D38-Q40 VanDerWaalsContact O-N 3.16Å; D38-Q40 WeakPolarHBondContact OD1-CB 3.4Å; D38-Q40 PolarHBondContact OD1-N 3.31Å; D38-K41 HydrophobicContact CB-CD 4.14Å; D38-K41 HydrophobicContact CB-CG 4.22Å; D38-K41 PolarHBondContact O-N 2.99Å; D38-K41 VanDerWaalsContact OD2-CE 3.22Å; D38-K41 WeakPolarHBondContact OD2-CE 3.25Å; D38-K41 IonicContact OD2-NZ 3.7Å
39P76.4Confident84.9Confident27 Ų2761.6 Ų61.618%0.17531%0.308CS..G310 helixtrans-61.2-24.8-177.4-23.336.2000113.4V37 K41 I42 Y48 Y49V37-P39 WeakPolarHBondContact O-CD 3.32Å; P39-K41 PolarHBondContact O-N 3.31Å; P39-I42 HydrophobicContact CB-CD1 4.43Å; P39-I42 WeakPolarHBondContact O-CB 3.33Å; P39-I42 PolarHBondContact O-N 2.66Å; P39-Y48 HydrophobicContact CB-CD1 4.13Å; P39-Y48 HydrophobicContact CB-CE1 4.22Å; P39-Y48 HydrophobicContact CG-CD1 4.14Å; P39-Y48 HydrophobicContact CG-CE1 3.7Å; P39-Y49 HydrophobicContact CB-CE2 4.38Å
40Q70.9Confident85.1Confident180 Ų18061 Ų6184%0.84130%0.302SS*.G310 helixtrans-69.3-17.9178.5-59.4-177.70.300112.7D38D38-Q40 PolarHBondContact O-N 2.92Å; D38-Q40 VanDerWaalsContact O-N 3.16Å; D38-Q40 WeakPolarHBondContact OD1-CB 3.4Å; D38-Q40 PolarHBondContact OD1-N 3.31Å
41K71.8Confident85.2Confident175 Ų17560.2 Ų60.276%0.76130%0.298SS*.G310 helixtrans-97.14.7178.2-61.2-178.5-176172.30112.8D38 P39D38-K41 HydrophobicContact CB-CD 4.14Å; D38-K41 HydrophobicContact CB-CG 4.22Å; D38-K41 PolarHBondContact O-N 2.99Å; D38-K41 VanDerWaalsContact OD2-CE 3.22Å; D38-K41 WeakPolarHBondContact OD2-CE 3.25Å; D38-K41 IonicContact OD2-NZ 3.7Å; P39-K41 PolarHBondContact O-N 3.31Å
42I76.3Confident85.3Confident49 Ų4958 Ų5825%0.25129%0.289SS..SBendtrans-92.4136.9179.9-55179.4000109.6V37 P39 S44 Y48V37-I42 HydrophobicContact CG1-CD1 3.58Å; V37-I42 HydrophobicContact CG1-CG1 3.72Å; P39-I42 HydrophobicContact CB-CD1 4.43Å; P39-I42 WeakPolarHBondContact O-CB 3.33Å; P39-I42 PolarHBondContact O-N 2.66Å; I42-S44 VanDerWaalsContact C-N 3.27Å; I42-S44 WeakPolarHBondContact CG2-O 3.48Å; I42-S44 PolarHBondContact O-N 2.9Å; I42-Y48 HydrophobicContact CD1-CD1 4.49Å; I42-Y48 HydrophobicContact CD1-CD2 3.25Å; I42-Y48 HydrophobicContact CD1-CE2 3.97Å; I42-Y48 HydrophobicContact CD1-CG 3.57Å
43S72.2Confident85.6Confident94 Ų9455.1 Ų55.166%0.65728%0.278SS*.SBendtrans-56.6-37.6178.4-168.70000113.3E169S43-E169 PolarHBondContact OG-OE2 2.82Å
44S82.4Confident86.1Confident13 Ų1349.9 Ų49.99%0.09126%0.255CS..  trans-130.896.7172.6178.90000110I42 V46 H47 Y48I42-S44 VanDerWaalsContact C-N 3.27Å; I42-S44 WeakPolarHBondContact CG2-O 3.48Å; I42-S44 PolarHBondContact O-N 2.9Å; S44-V46 PolarHBondContact O-N 3.46Å; S44-H47 WeakPolarHBondContact CB-ND1 3.31Å; S44-H47 PolarHBondContact O-N 2.95Å; S44-H47 PolarHBondContact OG-CD2 3.06Å; S44-H47 PolarHBondContact OG-CE1 2.65Å; S44-H47 PolarHBondContact OG-N 3.21Å; S44-H47 PolarHBondContact OG-ND1 3.26Å; S44-H47 PolarHBondContact OG-NE2 3.2Å; S44-Y48 PolarHBondContact O-N 2.98Å
45P87.6Confident86.5Confident25 Ų2549 Ų4916%0.16225%0.251CS..Hα-helixtrans-64.4-25.9175.2-19.230.8000112.4Y48 Y49 V75P45-Y48 WeakPolarHBondContact O-CB 3.36Å; P45-Y48 PolarHBondContact O-N 2.91Å; P45-Y49 HydrophobicContact CB-CE2 4.31Å; P45-Y49 WeakPolarHBondContact O-CD2 3.03Å; P45-Y49 PolarHBondContact O-N 3.36Å; P45-V75 HydrophobicContact CB-CG1 4.18Å; P45-V75 HydrophobicContact CG-CG1 4.44Å
46V90.8Very high87Confident2 Ų245.4 Ų45.41%0.01223%0.231CC..Hα-helixtrans-62.4-49.1176.6179.60000111.2S44 Y48 Y49 N50 A72 V75 I76 L88S44-V46 PolarHBondContact O-N 3.46Å; V46-Y48 PolarHBondContact O-N 3.18Å; V46-Y49 PolarHBondContact O-N 3.28Å; V46-Y49 VanDerWaalsContact O-N 3.14Å; V46-N50 WeakPolarHBondContact O-CB 3.15Å; V46-N50 VanDerWaalsContact O-CG 3.31Å; V46-N50 PolarHBondContact O-N 3.17Å; V46-A72 HydrophobicContact CG1-CB 4.15Å; V46-V75 HydrophobicContact CG2-CG1 4.43Å; V46-I76 HydrophobicContact CG2-CD1 3.5Å; V46-I76 VanDerWaalsContact CG2-CD1 3.5Å; V46-I76 HydrophobicContact CG2-CG1 3.47Å; V46-I76 VanDerWaalsContact CG2-CG1 3.47Å; V46-L88 HydrophobicContact CG1-CD2 4.37Å
47H92Very high87.9Confident19 Ų1940.2 Ų40.29%0.08821%0.206CC..Hα-helixtrans-60.2-35178-58170.4000111.3S44 L51 E137 E169S44-H47 WeakPolarHBondContact CB-ND1 3.31Å; S44-H47 PolarHBondContact O-N 2.95Å; S44-H47 PolarHBondContact OG-CD2 3.06Å; S44-H47 PolarHBondContact OG-CE1 2.65Å; S44-H47 PolarHBondContact OG-N 3.21Å; S44-H47 PolarHBondContact OG-ND1 3.26Å; S44-H47 PolarHBondContact OG-NE2 3.2Å; H47-L51 WeakPolarHBondContact O-CB 3.24Å; H47-L51 PolarHBondContact O-N 3.47Å; H47-L51 VanDerWaalsContact O-N 3.11Å; H47-E137 HydrophobicContact CB-CG 4.25Å; H47-E137 VanDerWaalsContact CD2-CG 3.49Å; H47-E137 WeakPolarHBondContact CD2-CG 3.47Å; H47-E137 IonicContact CD2-OE1 3.61Å; H47-E137 IonicContact CD2-OE2 2.71Å; H47-E137 PolarHBondContact CD2-OE2 3.17Å; H47-E137 VanDerWaalsContact CD2-OE2 3.23Å; H47-E137 IonicContact NE2-OE2 3.48Å; H47-E169 IonicContact CE1-OE1 2.63Å; H47-E169 IonicContact ND1-OE1 3.84Å
48Y93.3Very high88.6Confident27 Ų2738.2 Ų38.211%0.10620%0.195CC..Hα-helixtrans-62.1-51.7175.5173.1-88.4000111.3M34 V37 P39 I42 S44 P45 V46 L51 L52M34-Y48 HydrophobicContact CB-CE2 3.71Å; M34-Y48 HydrophobicContact CE-CD2 3.51Å; M34-Y48 HydrophobicContact CE-CE1 4.46Å; M34-Y48 HydrophobicContact CE-CE2 3.47Å; M34-Y48 VanDerWaalsContact CE-CE2 3.47Å; M34-Y48 HydrophobicContact CE-CG 4.06Å; M34-Y48 VanDerWaalsContact CE-O 3.31Å; M34-Y48 WeakPolarHBondContact CE-O 3.38Å; M34-Y48 HydrophobicContact CG-CE2 4.02Å; M34-Y48 PolarHBondContact O-OH 2.92Å; M34-Y48 VanDerWaalsContact O-OH 3.09Å; V37-Y48 HydrophobicContact CB-CE2 4.48Å; P39-Y48 HydrophobicContact CB-CD1 4.13Å; P39-Y48 HydrophobicContact CB-CE1 4.22Å; P39-Y48 HydrophobicContact CG-CD1 4.14Å; P39-Y48 HydrophobicContact CG-CE1 3.7Å; I42-Y48 HydrophobicContact CD1-CD1 4.49Å; I42-Y48 HydrophobicContact CD1-CD2 3.25Å; I42-Y48 HydrophobicContact CD1-CE2 3.97Å; I42-Y48 HydrophobicContact CD1-CG 3.57Å; S44-Y48 PolarHBondContact O-N 2.98Å; P45-Y48 WeakPolarHBondContact O-CB 3.36Å; P45-Y48 PolarHBondContact O-N 2.91Å; V46-Y48 PolarHBondContact O-N 3.18Å; Y48-L51 PolarHBondContact O-N 2.9Å; Y48-L52 HydrophobicContact CE1-CD2 3.99Å; Y48-L52 WeakPolarHBondContact O-CB 3.45Å; Y48-L52 PolarHBondContact O-N 3.25Å
49Y95.1Very high89.3Confident40 Ų4037.2 Ų37.216%0.15719%0.19CC..Hα-helixtrans-69.5-35.6-178.6-74-58.4000112.9P39 P45 V46 L52 G53 S68 K71 A72 V75P39-Y49 HydrophobicContact CB-CE2 4.38Å; P45-Y49 HydrophobicContact CB-CE2 4.31Å; P45-Y49 WeakPolarHBondContact O-CD2 3.03Å; P45-Y49 PolarHBondContact O-N 3.36Å; V46-Y49 PolarHBondContact O-N 3.28Å; V46-Y49 VanDerWaalsContact O-N 3.14Å; Y49-L52 PolarHBondContact O-N 2.86Å; Y49-G53 PolarHBondContact O-N 3.47Å; Y49-S68 WeakPolarHBondContact CB-O 3.33Å; Y49-K71 HydrophobicContact CD1-CB 4.17Å; Y49-K71 HydrophobicContact CD1-CG 4.16Å; Y49-K71 HydrophobicContact CD2-CG 4.2Å; Y49-K71 HydrophobicContact CE1-CB 4.21Å; Y49-K71 HydrophobicContact CE1-CG 3.74Å; Y49-K71 HydrophobicContact CE2-CG 3.8Å; Y49-K71 HydrophobicContact CG-CB 4.37Å; Y49-K71 HydrophobicContact CG-CG 4.39Å; Y49-A72 HydrophobicContact CG-CB 4.48Å; Y49-V75 HydrophobicContact CD2-CG2 4.39Å; Y49-V75 HydrophobicContact CE2-CG2 4.01Å
50N96.9Very high90.2Very high0 Ų038.8 Ų38.80%021%0.211CC..Hα-helixtrans-60.2-48.7173.6-75.2-11.4000112V46 G53 F54 N91 N94 E137V46-N50 WeakPolarHBondContact O-CB 3.15Å; V46-N50 VanDerWaalsContact O-CG 3.31Å; V46-N50 PolarHBondContact O-N 3.17Å; N50-G53 PolarHBondContact O-N 3.3Å; N50-F54 PolarHBondContact O-N 3.1Å; N50-F54 VanDerWaalsContact O-N 3.1Å; N50-N91 WeakPolarHBondContact OD1-CA 3.39Å; N50-N91 VanDerWaalsContact OD1-CB 3.25Å; N50-N91 WeakPolarHBondContact OD1-CB 3.47Å; N50-N91 PolarHBondContact OD1-ND2 3.44Å; N50-N94 PolarHBondContact O-ND2 3.46Å; N50-E137 VanDerWaalsContact CB-OE1 3.26Å; N50-E137 WeakPolarHBondContact CB-OE1 3.03Å; N50-E137 PolarHBondContact ND2-OE1 3.32Å; N50-E137 PolarHBondContact ND2-OE2 2.92Å
51L96.4Very high91.4Very high1 Ų131.8 Ų31.81%0.00518%0.181CC..Hα-helixtrans-66.2-39.8177179.461000111.7M30 M34 H47 Y48 G53 F54 I55 T141 K144M30-L51 HydrophobicContact CE-CD1 4.35Å; M30-L51 HydrophobicContact CE-CD2 4.01Å; M34-L51 HydrophobicContact CE-CB 4.45Å; M34-L51 HydrophobicContact CE-CD2 4.45Å; M34-L51 HydrophobicContact CE-CG 4.43Å; M34-L51 HydrophobicContact SD-CD2 4.19Å; M34-L51 HydrophobicContact SD-CG 4.36Å; H47-L51 WeakPolarHBondContact O-CB 3.24Å; H47-L51 PolarHBondContact O-N 3.47Å; H47-L51 VanDerWaalsContact O-N 3.11Å; Y48-L51 PolarHBondContact O-N 2.9Å; L51-G53 VanDerWaalsContact C-N 3.35Å; L51-F54 HydrophobicContact CD1-CD1 4.26Å; L51-F54 PolarHBondContact O-N 3Å; L51-I55 HydrophobicContact CD1-CD1 4.11Å; L51-I55 HydrophobicContact CD1-CG1 4.29Å; L51-I55 HydrophobicContact CG-CD1 3.85Å; L51-I55 HydrophobicContact CG-CG1 4.45Å; L51-I55 VanDerWaalsContact O-CG1 3.27Å; L51-I55 WeakPolarHBondContact O-CG1 3.29Å; L51-I55 PolarHBondContact O-N 3.06Å; L51-T141 HydrophobicContact CD1-CG2 4.25Å; L51-K144 HydrophobicContact CD2-CD 3.42Å; L51-K144 VanDerWaalsContact CD2-CD 3.42Å
52L96.5Very high92.4Very high13 Ų1325.7 Ų25.77%0.06816%0.157CC..Hα-helixtrans-62.7-43177.8-175.557.8000111.4K31 M34 Y48 Y49 I55 Q56 S68K31-L52 HydrophobicContact CG-CD1 4.44Å; M34-L52 HydrophobicContact CE-CB 3.81Å; M34-L52 HydrophobicContact CE-CD1 4.42Å; Y48-L52 HydrophobicContact CE1-CD2 3.99Å; Y48-L52 WeakPolarHBondContact O-CB 3.45Å; Y48-L52 PolarHBondContact O-N 3.25Å; Y49-L52 PolarHBondContact O-N 2.86Å; L52-I55 PolarHBondContact O-N 3.12Å; L52-Q56 HydrophobicContact CD1-CG 4.2Å; L52-Q56 HydrophobicContact CG-CG 4.42Å; L52-Q56 WeakPolarHBondContact O-CB 3.48Å; L52-Q56 WeakPolarHBondContact O-CG 3.23Å; L52-Q56 PolarHBondContact O-N 3.13Å; L52-Q56 PolarHBondContact O-OE1 2.94Å; L52-S68 WeakPolarHBondContact CD2-OG 3.41Å
53G97.3Very high93.3Very high0 Ų030.7 Ų30.70%017%0.173CC..Hα-helixtrans-59.6-46.1175.100000112.3Y49 N50 L51 I55 Q56 K57 A65Y49-G53 PolarHBondContact O-N 3.47Å; N50-G53 PolarHBondContact O-N 3.3Å; L51-G53 VanDerWaalsContact C-N 3.35Å; G53-I55 PolarHBondContact O-N 2.56Å; G53-Q56 PolarHBondContact O-N 3.44Å; G53-K57 WeakPolarHBondContact O-CB 3.37Å; G53-K57 PolarHBondContact O-N 3.12Å; G53-A65 WeakPolarHBondContact O-CB 3.48Å
54F97.8Very high94.5Very high3 Ų328.9 Ų28.91%0.01315%0.154CC..Hα-helixtrans-58.8-46.6173.3167.2-99.3000112.6H15 F16 L20 Q22 L27 N50 L51 K57 S58H15-F54 HydrophobicContact CB-CB 3.58Å; H15-F54 HydrophobicContact CB-CD1 4.28Å; H15-F54 HydrophobicContact CB-CD2 3.57Å; H15-F54 HydrophobicContact CB-CE2 4.35Å; H15-F54 HydrophobicContact CB-CG 3.53Å; H15-F54 WeakPolarHBondContact O-CE2 3.4Å; F16-F54 AromaticContact CD1-CD2 3.88Å; F16-F54 HydrophobicContact CD1-CD2 3.88Å; F16-F54 HydrophobicContact CD1-CE2 4.1Å; F16-F54 HydrophobicContact CD2-CD2 4.49Å; F16-F54 AromaticContact CE1-CD2 3.82Å; F16-F54 HydrophobicContact CE1-CD2 3.82Å; F16-F54 HydrophobicContact CE1-CE2 4.32Å; F16-F54 HydrophobicContact CE2-CD2 4.43Å; F16-F54 HydrophobicContact CG-CD2 4.24Å; F16-F54 HydrophobicContact CZ-CD2 4.1Å; L20-F54 HydrophobicContact CB-CE1 4.18Å; L20-F54 HydrophobicContact CB-CZ 4.07Å; L20-F54 HydrophobicContact CD1-CD1 4.11Å; L20-F54 HydrophobicContact CD1-CE1 3.79Å; L20-F54 HydrophobicContact CD1-CZ 4.06Å; Q22-F54 HydrophobicContact CG-CZ 4.32Å; L27-F54 HydrophobicContact CD2-CE1 4.12Å; N50-F54 PolarHBondContact O-N 3.1Å; N50-F54 VanDerWaalsContact O-N 3.1Å; L51-F54 HydrophobicContact CD1-CD1 4.26Å; L51-F54 PolarHBondContact O-N 3Å; F54-K57 PolarHBondContact O-N 3.29Å; F54-S58 WeakPolarHBondContact CE2-OG 3.36Å; F54-S58 VanDerWaalsContact O-CB 3.28Å; F54-S58 WeakPolarHBondContact O-CB 3.26Å; F54-S58 PolarHBondContact O-N 2.63Å; F54-S58 PolarHBondContact O-OG 2.74Å
55I97.3Very high95.2Very high0 Ų028.3 Ų28.30%015%0.15CC..Hα-helixtrans-62.3-47.7179.8-72166.3000110.5L27 M30 K31 M34 L51 L52 G53 S58 L59L27-I55 HydrophobicContact CB-CG2 4.31Å; L27-I55 HydrophobicContact CD2-CG1 4.09Å; M30-I55 HydrophobicContact CB-CD1 3.94Å; M30-I55 HydrophobicContact CE-CD1 4.26Å; K31-I55 HydrophobicContact CB-CG2 3.97Å; M34-I55 HydrophobicContact SD-CD1 3.69Å; L51-I55 HydrophobicContact CD1-CD1 4.11Å; L51-I55 HydrophobicContact CD1-CG1 4.29Å; L51-I55 HydrophobicContact CG-CD1 3.85Å; L51-I55 HydrophobicContact CG-CG1 4.45Å; L51-I55 VanDerWaalsContact O-CG1 3.27Å; L51-I55 WeakPolarHBondContact O-CG1 3.29Å; L51-I55 PolarHBondContact O-N 3.06Å; L52-I55 PolarHBondContact O-N 3.12Å; G53-I55 PolarHBondContact O-N 2.56Å; I55-S58 PolarHBondContact O-N 3.37Å; I55-L59 HydrophobicContact CG2-CD1 3.8Å; I55-L59 HydrophobicContact CG2-CG 4.47Å; I55-L59 WeakPolarHBondContact O-CB 3.44Å; I55-L59 VanDerWaalsContact O-CG 3.25Å; I55-L59 WeakPolarHBondContact O-CG 3.31Å; I55-L59 PolarHBondContact O-N 2.69Å
56Q97.1Very high95.6Very high17 Ų1728.3 Ų28.38%0.07915%0.149CC..Hα-helixtrans-62.5-45.1179.8-76.1165-28.200111.2L52 G53 S58 L59 G60 S61 E64 A65 S68L52-Q56 HydrophobicContact CD1-CG 4.2Å; L52-Q56 HydrophobicContact CG-CG 4.42Å; L52-Q56 WeakPolarHBondContact O-CB 3.48Å; L52-Q56 WeakPolarHBondContact O-CG 3.23Å; L52-Q56 PolarHBondContact O-N 3.13Å; L52-Q56 PolarHBondContact O-OE1 2.94Å; G53-Q56 PolarHBondContact O-N 3.44Å; Q56-S58 VanDerWaalsContact C-N 3.34Å; Q56-S58 PolarHBondContact O-N 3.49Å; Q56-L59 CarbonylContact O-C 3.59Å; Q56-L59 PolarHBondContact O-N 3.29Å; Q56-L59 VanDerWaalsContact O-N 3.14Å; Q56-G60 PolarHBondContact O-N 3.28Å; Q56-G60 VanDerWaalsContact O-N 3.17Å; Q56-S61 PolarHBondContact O-N 2.88Å; Q56-E64 HydrophobicContact CB-CB 4.43Å; Q56-E64 HydrophobicContact CG-CB 4.19Å; Q56-E64 PolarHBondContact OE1-O 3.07Å; Q56-A65 HydrophobicContact CB-CB 3.9Å; Q56-S68 PolarHBondContact NE2-OG 2.85Å; Q56-S68 PolarHBondContact OE1-OG 3.49Å
57K96.8Very high95.9Very high31 Ų3132.4 Ų32.414%0.13517%0.168CC..Hα-helixtrans-61.2-45176.3178.856.7-173.5171.40111.3F16 G53 F54 L59 G60 D62 A65 V98 Y101F16-K57 HydrophobicContact CE1-CB 4.25Å; F16-K57 HydrophobicContact CE1-CG 3.85Å; F16-K57 HydrophobicContact CZ-CB 4.02Å; F16-K57 HydrophobicContact CZ-CG 3.89Å; G53-K57 WeakPolarHBondContact O-CB 3.37Å; G53-K57 PolarHBondContact O-N 3.12Å; F54-K57 PolarHBondContact O-N 3.29Å; K57-L59 PolarHBondContact O-N 3.44Å; K57-G60 PolarHBondContact O-N 2.83Å; K57-D62 WeakPolarHBondContact CD-OD1 3.22Å; K57-D62 WeakPolarHBondContact CE-OD1 3.31Å; K57-D62 IonicContact NZ-OD1 3.43Å; K57-D62 PolarHBondContact NZ-OD1 3.29Å; K57-D62 IonicContact NZ-OD2 3.55Å; K57-D62 PolarHBondContact NZ-OD2 3.09Å; K57-A65 HydrophobicContact CB-CB 3.79Å; K57-V98 HydrophobicContact CB-CG2 4.4Å; K57-V98 HydrophobicContact CG-CG2 4.26Å; K57-Y101 HydrophobicContact CG-CD2 4.47Å
58S95.8Very high96.1Very high23 Ų2332 Ų3216%0.16117%0.167CC..Hα-helixtrans-65.8-21.8178.7-590000113.2L27 F54 I55 Q56L27-S58 VanDerWaalsContact CD1-CB 3.45Å; F54-S58 WeakPolarHBondContact CE2-OG 3.36Å; F54-S58 VanDerWaalsContact O-CB 3.28Å; F54-S58 WeakPolarHBondContact O-CB 3.26Å; F54-S58 PolarHBondContact O-N 2.63Å; F54-S58 PolarHBondContact O-OG 2.74Å; I55-S58 PolarHBondContact O-N 3.37Å; Q56-S58 VanDerWaalsContact C-N 3.34Å; Q56-S58 PolarHBondContact O-N 3.49Å
59L95.4Very high96.3Very high43 Ų4330.7 Ų30.723%0.22516%0.162CC..THydrogen-bonded Turntrans-93.63.8173.6-67.1174.9000113.3L27 Q28 K31 I55 Q56 K57L27-L59 HydrophobicContact CB-CD1 4.4Å; L27-L59 HydrophobicContact CB-CD2 4.06Å; L27-L59 HydrophobicContact CB-CG 4.24Å; Q28-L59 HydrophobicContact CG-CD1 4.14Å; Q28-L59 HydrophobicContact CG-CD2 3.87Å; K31-L59 HydrophobicContact CD-CD1 4.24Å; I55-L59 HydrophobicContact CG2-CD1 3.8Å; I55-L59 HydrophobicContact CG2-CG 4.47Å; I55-L59 WeakPolarHBondContact O-CB 3.44Å; I55-L59 VanDerWaalsContact O-CG 3.25Å; I55-L59 WeakPolarHBondContact O-CG 3.31Å; I55-L59 PolarHBondContact O-N 2.69Å; Q56-L59 CarbonylContact O-C 3.59Å; Q56-L59 PolarHBondContact O-N 3.29Å; Q56-L59 VanDerWaalsContact O-N 3.14Å; K57-L59 PolarHBondContact O-N 3.44Å
60G95.1Very high96.3Very high59 Ų5932.5 Ų32.561%0.60817%0.171SC*.THydrogen-bonded Turntrans81.513.8178.600000115.2Q56 K57 D62Q56-G60 PolarHBondContact O-N 3.28Å; Q56-G60 VanDerWaalsContact O-N 3.17Å; K57-G60 PolarHBondContact O-N 2.83Å; G60-D62 PolarHBondContact O-N 2.99Å
61S95Very high96.2Very high33 Ų3336.4 Ų36.423%0.23119%0.189CC..  trans-95.872177.1-56.30000110.6Q56 R63 E64 A65Q56-S61 PolarHBondContact O-N 2.88Å; S61-R63 PolarHBondContact O-N 3.43Å; S61-E64 WeakPolarHBondContact CB-OE2 3.39Å; S61-E64 PolarHBondContact O-N 3.33Å; S61-A65 WeakPolarHBondContact O-CB 3.36Å; S61-A65 PolarHBondContact O-N 3.24Å
62D94.4Very high96Very high48 Ų4836.4 Ų36.426%0.25719%0.188SC..Hα-helixtrans-63.7-41.3-169.4-72.80.7000113.9K57 G60 A65 L66 L102K57-D62 WeakPolarHBondContact CD-OD1 3.22Å; K57-D62 WeakPolarHBondContact CE-OD1 3.31Å; K57-D62 IonicContact NZ-OD1 3.43Å; K57-D62 PolarHBondContact NZ-OD1 3.29Å; K57-D62 IonicContact NZ-OD2 3.55Å; K57-D62 PolarHBondContact NZ-OD2 3.09Å; G60-D62 PolarHBondContact O-N 2.99Å; D62-A65 WeakPolarHBondContact O-CB 3.37Å; D62-A65 PolarHBondContact O-N 3.1Å; D62-L66 PolarHBondContact O-N 3.11Å; D62-L66 VanDerWaalsContact O-N 3.14Å; D62-L102 HydrophobicContact CB-CD2 3.91Å; D62-L102 VanDerWaalsContact OD2-CD2 3.3Å; D62-L102 WeakPolarHBondContact OD2-CD2 3.47Å
63R94.5Very high95.7Very high154 Ų15436.6 Ų36.658%0.58119%0.189SC*.Hα-helixtrans-65.3-48.9179.2-177.6-175.966106.7-1.3110.8S61 A65 L66 E67S61-R63 PolarHBondContact O-N 3.43Å; R63-A65 PolarHBondContact O-N 3.35Å; R63-L66 PolarHBondContact O-N 3.49Å; R63-E67 IonicContact CZ-OE1 2.69Å; R63-E67 IonicContact NE-OE1 3.31Å; R63-E67 IonicContact NH1-OE1 2.69Å; R63-E67 PolarHBondContact NH1-OE1 2.97Å; R63-E67 WeakPolarHBondContact O-CG 3.24Å; R63-E67 PolarHBondContact O-N 3Å
64E96.4Very high95.4Very high56 Ų5638.5 Ų38.526%0.26220%0.203SC..Hα-helixtrans-62-36.2178.6-66.772.6-164.200110.8Q56 S61 E67 S68Q56-E64 HydrophobicContact CB-CB 4.43Å; Q56-E64 HydrophobicContact CG-CB 4.19Å; Q56-E64 PolarHBondContact OE1-O 3.07Å; S61-E64 WeakPolarHBondContact CB-OE2 3.39Å; S61-E64 PolarHBondContact O-N 3.33Å; E64-E67 PolarHBondContact O-N 3.26Å; E64-S68 PolarHBondContact O-N 3.2Å; E64-S68 PolarHBondContact O-OG 3.39Å
65A97.3Very high94.8Very high0 Ų039.2 Ų39.20%021%0.207CC..Hα-helixtrans-60.3-47.5175.600000112.2G53 Q56 K57 S61 D62 R63 S68 L69G53-A65 WeakPolarHBondContact O-CB 3.48Å; Q56-A65 HydrophobicContact CB-CB 3.9Å; K57-A65 HydrophobicContact CB-CB 3.79Å; S61-A65 WeakPolarHBondContact O-CB 3.36Å; S61-A65 PolarHBondContact O-N 3.24Å; D62-A65 WeakPolarHBondContact O-CB 3.37Å; D62-A65 PolarHBondContact O-N 3.1Å; R63-A65 PolarHBondContact O-N 3.35Å; A65-S68 PolarHBondContact O-N 3.43Å; A65-L69 WeakPolarHBondContact O-CG 3.45Å; A65-L69 PolarHBondContact O-N 3.24Å
66L97.4Very high94.2Very high25 Ų2539.7 Ų39.713%0.13121%0.209CC..Hα-helixtrans-62.8-45.6174.8-77.2177.6000111.8D62 R63 S68 L69 Q70 L95 V98 Y99 L102D62-L66 PolarHBondContact O-N 3.11Å; D62-L66 VanDerWaalsContact O-N 3.14Å; R63-L66 PolarHBondContact O-N 3.49Å; L66-S68 VanDerWaalsContact C-N 3.28Å; L66-S68 PolarHBondContact O-N 2.69Å; L66-L69 PolarHBondContact O-N 2.88Å; L66-Q70 WeakPolarHBondContact O-CB 3.22Å; L66-Q70 VanDerWaalsContact O-CG 3.28Å; L66-Q70 WeakPolarHBondContact O-CG 3.42Å; L66-Q70 PolarHBondContact O-N 3.34Å; L66-L95 HydrophobicContact CD2-CD2 4.02Å; L66-V98 HydrophobicContact CD2-CB 4.28Å; L66-V98 HydrophobicContact CD2-CG1 3.53Å; L66-V98 HydrophobicContact CG-CG1 3.8Å; L66-Y99 HydrophobicContact CD1-CE1 4.14Å; L66-Y99 HydrophobicContact CD2-CD1 4.48Å; L66-Y99 HydrophobicContact CD2-CD2 4.44Å; L66-Y99 HydrophobicContact CD2-CE1 4.02Å; L66-Y99 HydrophobicContact CD2-CE2 3.93Å; L66-L102 HydrophobicContact CD1-CD1 3.57Å; L66-L102 HydrophobicContact CG-CD1 4.19Å
67E96.6Very high93.5Very high89 Ų8945.5 Ų45.542%0.41624%0.236SC..Hα-helixtrans-56.3-43.5177.8-72.9171.4-177.300111.2R63 E64 K71R63-E67 IonicContact CZ-OE1 2.69Å; R63-E67 IonicContact NE-OE1 3.31Å; R63-E67 IonicContact NH1-OE1 2.69Å; R63-E67 PolarHBondContact NH1-OE1 2.97Å; R63-E67 WeakPolarHBondContact O-CG 3.24Å; R63-E67 PolarHBondContact O-N 3Å; E64-E67 PolarHBondContact O-N 3.26Å; E67-K71 WeakPolarHBondContact O-CB 3.35Å; E67-K71 PolarHBondContact O-N 3.37Å
68S96.4Very high92.6Very high9 Ų950.9 Ų50.96%0.06326%0.262CS..Hα-helixtrans-63.5-49.2175.4-66.10000112Y49 L52 Q56 E64 A65 L66 Q70 K71 A72Y49-S68 WeakPolarHBondContact CB-O 3.33Å; L52-S68 WeakPolarHBondContact CD2-OG 3.41Å; Q56-S68 PolarHBondContact NE2-OG 2.85Å; Q56-S68 PolarHBondContact OE1-OG 3.49Å; E64-S68 PolarHBondContact O-N 3.2Å; E64-S68 PolarHBondContact O-OG 3.39Å; A65-S68 PolarHBondContact O-N 3.43Å; L66-S68 VanDerWaalsContact C-N 3.28Å; L66-S68 PolarHBondContact O-N 2.69Å; S68-Q70 PolarHBondContact O-N 3.19Å; S68-K71 WeakPolarHBondContact O-CB 3.26Å; S68-K71 PolarHBondContact O-N 3.14Å; S68-K71 VanDerWaalsContact O-N 3.16Å; S68-A72 PolarHBondContact O-N 2.78Å; S68-A72 VanDerWaalsContact O-N 3.1Å
69L97Very high91.5Very high0 Ų053.7 Ų53.70%027%0.273CS..Hα-helixtrans-64.7-40.8-178.1-67.9176.4000112.4A65 L66 K71 A72 E73 N91 N94 L95 V98A65-L69 WeakPolarHBondContact O-CG 3.45Å; A65-L69 PolarHBondContact O-N 3.24Å; L66-L69 PolarHBondContact O-N 2.88Å; L69-K71 VanDerWaalsContact C-N 3.3Å; L69-K71 PolarHBondContact O-N 2.66Å; L69-A72 VanDerWaalsContact O-CB 3.27Å; L69-A72 WeakPolarHBondContact O-CB 3.43Å; L69-A72 PolarHBondContact O-N 3.48Å; L69-A72 VanDerWaalsContact O-N 3.16Å; L69-E73 PolarHBondContact O-N 3.18Å; L69-N91 PolarHBondContact O-ND2 2.96Å; L69-N94 HydrophobicContact CD1-CB 4Å; L69-N94 HydrophobicContact CD2-CB 3.8Å; L69-L95 HydrophobicContact CB-CD1 4.45Å; L69-L95 HydrophobicContact CB-CD2 3.53Å; L69-L95 HydrophobicContact CB-CG 3.87Å; L69-L95 HydrophobicContact CD1-CD2 3.88Å; L69-L95 HydrophobicContact CD1-CG 4.07Å; L69-L95 HydrophobicContact CG-CD2 4.36Å; L69-V98 HydrophobicContact CD1-CB 4.31Å; L69-V98 HydrophobicContact CD1-CG2 3.67Å
70Q95.5Very high89.6Confident78 Ų7854.7 Ų54.736%0.36429%0.294SS..Hα-helixtrans-64.5-36.3173.8-71.6171.6-15.800111.4L66 S68 A72 E73 S74L66-Q70 WeakPolarHBondContact O-CB 3.22Å; L66-Q70 VanDerWaalsContact O-CG 3.28Å; L66-Q70 WeakPolarHBondContact O-CG 3.42Å; L66-Q70 PolarHBondContact O-N 3.34Å; S68-Q70 PolarHBondContact O-N 3.19Å; Q70-A72 VanDerWaalsContact C-N 3.26Å; Q70-A72 PolarHBondContact O-N 3.29Å; Q70-E73 WeakPolarHBondContact O-CB 3.3Å; Q70-E73 PolarHBondContact O-N 3.14Å; Q70-E73 VanDerWaalsContact O-N 3.11Å; Q70-S74 PolarHBondContact O-N 3.16Å; Q70-S74 PolarHBondContact O-OG 3.31Å
71K93.9Very high88Confident83 Ų8355.4 Ų55.436%0.36129%0.286SS..Hα-helixtrans-63.2-34.6174.5-171.358.9-179.5167.90111.9Y49 E67 S68 L69 E73 S74 V75Y49-K71 HydrophobicContact CD1-CB 4.17Å; Y49-K71 HydrophobicContact CD1-CG 4.16Å; Y49-K71 HydrophobicContact CD2-CG 4.2Å; Y49-K71 HydrophobicContact CE1-CB 4.21Å; Y49-K71 HydrophobicContact CE1-CG 3.74Å; Y49-K71 HydrophobicContact CE2-CG 3.8Å; Y49-K71 HydrophobicContact CG-CB 4.37Å; Y49-K71 HydrophobicContact CG-CG 4.39Å; E67-K71 WeakPolarHBondContact O-CB 3.35Å; E67-K71 PolarHBondContact O-N 3.37Å; S68-K71 WeakPolarHBondContact O-CB 3.26Å; S68-K71 PolarHBondContact O-N 3.14Å; S68-K71 VanDerWaalsContact O-N 3.16Å; L69-K71 VanDerWaalsContact C-N 3.3Å; L69-K71 PolarHBondContact O-N 2.66Å; K71-E73 VanDerWaalsContact C-N 3.35Å; K71-S74 PolarHBondContact O-N 3.29Å; K71-V75 VanDerWaalsContact O-CG2 3.32Å; K71-V75 WeakPolarHBondContact O-CG2 3.12Å; K71-V75 PolarHBondContact O-N 3.11Å
72A92.3Very high86.4Confident0 Ų061 Ų610%031%0.309CS..Hα-helixtrans-60.9-42.317200000112V46 Y49 S68 L69 Q70 V75 I76 N91V46-A72 HydrophobicContact CG1-CB 4.15Å; Y49-A72 HydrophobicContact CG-CB 4.48Å; S68-A72 PolarHBondContact O-N 2.78Å; S68-A72 VanDerWaalsContact O-N 3.1Å; L69-A72 VanDerWaalsContact O-CB 3.27Å; L69-A72 WeakPolarHBondContact O-CB 3.43Å; L69-A72 PolarHBondContact O-N 3.48Å; L69-A72 VanDerWaalsContact O-N 3.16Å; Q70-A72 VanDerWaalsContact C-N 3.26Å; Q70-A72 PolarHBondContact O-N 3.29Å; A72-V75 PolarHBondContact O-N 3.33Å; A72-I76 PolarHBondContact O-N 3.13Å; A72-N91 VanDerWaalsContact CB-ND2 3.32Å; A72-N91 WeakPolarHBondContact CB-ND2 3.42Å
73E91.2Very high84.8Confident17 Ų1766.4 Ų66.48%0.07933%0.332CS..Hα-helixtrans-62.4-46.8174.9-62-175.2111.300111.7L69 Q70 K71 V75 I76 Q77 L88 N91 K92 L95 Y111L69-E73 PolarHBondContact O-N 3.18Å; Q70-E73 WeakPolarHBondContact O-CB 3.3Å; Q70-E73 PolarHBondContact O-N 3.14Å; Q70-E73 VanDerWaalsContact O-N 3.11Å; K71-E73 VanDerWaalsContact C-N 3.35Å; E73-V75 VanDerWaalsContact C-N 3.3Å; E73-V75 PolarHBondContact O-N 3.5Å; E73-I76 PolarHBondContact O-N 2.91Å; E73-I76 VanDerWaalsContact O-N 3.14Å; E73-Q77 WeakPolarHBondContact O-CG 3.41Å; E73-Q77 PolarHBondContact O-N 2.84Å; E73-L88 HydrophobicContact CG-CD2 4.38Å; E73-N91 WeakPolarHBondContact CG-OD1 3.16Å; E73-K92 WeakPolarHBondContact OE1-CE 3.3Å; E73-K92 IonicContact OE1-NZ 3.27Å; E73-K92 PolarHBondContact OE1-NZ 3.38Å; E73-L95 VanDerWaalsContact CD-CD1 3.45Å; E73-L95 HydrophobicContact CG-CD1 4.09Å; E73-L95 WeakPolarHBondContact OE2-CD1 3.28Å; E73-Y111 PolarHBondContact OE2-OH 2.97Å
74S90Very high83.9Confident41 Ų4159.8 Ų59.829%0.28731%0.309SS..Hα-helixtrans-60-39.8179.1-52.30000112.3Q70 K71 I76 Q77 E78Q70-S74 PolarHBondContact O-N 3.16Å; Q70-S74 PolarHBondContact O-OG 3.31Å; K71-S74 PolarHBondContact O-N 3.29Å; S74-I76 VanDerWaalsContact C-N 3.27Å; S74-I76 PolarHBondContact O-N 3.35Å; S74-Q77 PolarHBondContact O-N 3.14Å; S74-E78 WeakPolarHBondContact O-CG 3.44Å; S74-E78 PolarHBondContact O-N 2.99Å
75V86.6Confident83.1Confident18 Ų1858.4 Ų58.411%0.10931%0.307CS..Hα-helixtrans-60.4-37.6177.7167.50000111.9P45 V46 Y49 K71 A72 E73 Q79P45-V75 HydrophobicContact CB-CG1 4.18Å; P45-V75 HydrophobicContact CG-CG1 4.44Å; V46-V75 HydrophobicContact CG2-CG1 4.43Å; Y49-V75 HydrophobicContact CD2-CG2 4.39Å; Y49-V75 HydrophobicContact CE2-CG2 4.01Å; K71-V75 VanDerWaalsContact O-CG2 3.32Å; K71-V75 WeakPolarHBondContact O-CG2 3.12Å; K71-V75 PolarHBondContact O-N 3.11Å; A72-V75 PolarHBondContact O-N 3.33Å; E73-V75 VanDerWaalsContact C-N 3.3Å; E73-V75 PolarHBondContact O-N 3.5Å; V75-Q79 WeakPolarHBondContact O-CG 3.48Å; V75-Q79 PolarHBondContact O-NE2 2.97Å
76I84.2Confident82.6Confident9 Ų959 Ų595%0.04631%0.31CS..Hα-helixtrans-75.5-40.5177.4-69.6-56.5000111.4V46 A72 E73 S74 E78 Q79 G80 R87 L88V46-I76 HydrophobicContact CG2-CD1 3.5Å; V46-I76 VanDerWaalsContact CG2-CD1 3.5Å; V46-I76 HydrophobicContact CG2-CG1 3.47Å; V46-I76 VanDerWaalsContact CG2-CG1 3.47Å; A72-I76 PolarHBondContact O-N 3.13Å; E73-I76 PolarHBondContact O-N 2.91Å; E73-I76 VanDerWaalsContact O-N 3.14Å; S74-I76 VanDerWaalsContact C-N 3.27Å; S74-I76 PolarHBondContact O-N 3.35Å; I76-E78 PolarHBondContact O-N 3.3Å; I76-Q79 WeakPolarHBondContact O-CB 3.41Å; I76-Q79 PolarHBondContact O-N 3.27Å; I76-G80 PolarHBondContact O-N 3.36Å; I76-R87 HydrophobicContact CD1-CB 4.1Å; I76-L88 HydrophobicContact CB-CD1 4.03Å; I76-L88 HydrophobicContact CB-CD2 4.07Å; I76-L88 HydrophobicContact CB-CG 4.08Å; I76-L88 HydrophobicContact CG1-CD1 4.46Å; I76-L88 HydrophobicContact CG1-CD2 3.7Å; I76-L88 HydrophobicContact CG1-CG 3.95Å; I76-L88 HydrophobicContact CG2-CD1 3.84Å; I76-L88 HydrophobicContact CG2-CG 4.03Å
77Q81.4Confident82.1Confident139 Ų13961.2 Ų61.265%0.6532%0.317SS*.Hα-helixtrans-58.6-38.1176.1-71172.4-4.100112.1E73 S74 Q79 G80E73-Q77 WeakPolarHBondContact O-CG 3.41Å; E73-Q77 PolarHBondContact O-N 2.84Å; S74-Q77 PolarHBondContact O-N 3.14Å; Q77-Q79 VanDerWaalsContact C-N 3.26Å; Q77-Q79 PolarHBondContact O-N 3.09Å; Q77-G80 PolarHBondContact O-N 2.98Å
78E78.9Confident81.9Confident145 Ų14557.6 Ų57.668%0.67830%0.301SS*.THydrogen-bonded Turntrans-66.6-22.4174.8-71.3169-16200113.3S74 I76S74-E78 WeakPolarHBondContact O-CG 3.44Å; S74-E78 PolarHBondContact O-N 2.99Å; I76-E78 PolarHBondContact O-N 3.3Å
79Q71.4Confident81.9Confident82 Ų8257.4 Ų57.438%0.38330%0.299SS..THydrogen-bonded Turntrans-86.7-17-180-69.7172.923.500113.7V75 I76 Q77 T81 T84V75-Q79 WeakPolarHBondContact O-CG 3.48Å; V75-Q79 PolarHBondContact O-NE2 2.97Å; I76-Q79 WeakPolarHBondContact O-CB 3.41Å; I76-Q79 PolarHBondContact O-N 3.27Å; Q77-Q79 VanDerWaalsContact C-N 3.26Å; Q77-Q79 PolarHBondContact O-N 3.09Å; Q79-T81 PolarHBondContact O-N 3.45Å; Q79-T84 HydrophobicContact CB-CG2 4.36Å
80G55.8Low81.9Confident64 Ų6457.5 Ų57.566%0.6630%0.3SS*.  trans73.814.6155.100000118.9I76 Q77I76-G80 PolarHBondContact O-N 3.36Å; Q77-G80 PolarHBondContact O-N 2.98Å
81T62.5Low81.9Confident73 Ų7353.8 Ų53.845%0.44828%0.282SS..  trans-123.7144.6176.370.70000113.4Q79 E83 T84Q79-T81 PolarHBondContact O-N 3.45Å; T81-E83 PolarHBondContact O-N 3.03Å; T81-T84 PolarHBondContact O-N 3.43Å; T81-T84 PolarHBondContact O-OG1 3.14Å; T81-T84 VanDerWaalsContact OG1-CG2 3.25Å; T81-T84 WeakPolarHBondContact OG1-CG2 3.35Å
82E59.7Low82.1Confident152 Ų15251 Ų5171%0.7127%0.27SS*.Hα-helixtrans-58.7-33.1175.9-157.2169.5-164.100111.6T84 A85E82-T84 PolarHBondContact O-N 3.34Å; E82-A85 VanDerWaalsContact O-CB 3.26Å; E82-A85 WeakPolarHBondContact O-CB 3.28Å; E82-A85 PolarHBondContact O-N 3.09Å; E82-A85 VanDerWaalsContact O-N 3.07Å
83E62.3Low82.3Confident161 Ų16151.1 Ų51.175%0.75227%0.271SS*.Hα-helixtrans-63.8-18.4173.6-163.2176.1-173.400113.7T81 V86T81-E83 PolarHBondContact O-N 3.03Å; E83-V86 WeakPolarHBondContact O-CG2 3.36Å
84T74.5Confident82.7Confident14 Ų1450.3 Ų50.39%0.08627%0.267CS..Hα-helixtrans-87.9-14.5174.961.10000113.3Q79 T81 E82 V86 R87Q79-T84 HydrophobicContact CB-CG2 4.36Å; T81-T84 PolarHBondContact O-N 3.43Å; T81-T84 PolarHBondContact O-OG1 3.14Å; T81-T84 VanDerWaalsContact OG1-CG2 3.25Å; T81-T84 WeakPolarHBondContact OG1-CG2 3.35Å; E82-T84 PolarHBondContact O-N 3.34Å; T84-V86 VanDerWaalsContact C-N 3.29Å; T84-V86 PolarHBondContact O-N 3.31Å; T84-R87 WeakPolarHBondContact O-CB 3.39Å; T84-R87 PolarHBondContact O-N 3.42Å; T84-R87 VanDerWaalsContact O-N 3.11Å
85A79.9Confident83.1Confident27 Ų2748.3 Ų48.322%0.22325%0.253CS..Hα-helixtrans-62.8-34.7-178.600000112.2E82 R87 L88 L118E82-A85 VanDerWaalsContact O-CB 3.26Å; E82-A85 WeakPolarHBondContact O-CB 3.28Å; E82-A85 PolarHBondContact O-N 3.09Å; E82-A85 VanDerWaalsContact O-N 3.07Å; A85-R87 PolarHBondContact O-N 3.43Å; A85-R87 VanDerWaalsContact O-N 3.1Å; A85-L88 WeakPolarHBondContact O-CB 3.47Å; A85-L88 PolarHBondContact O-N 2.8Å; A85-L118 HydrophobicContact CB-CD1 3.77Å; A85-L118 WeakPolarHBondContact O-CD2 3.38Å
86V86.9Confident83.6Confident12 Ų1247.5 Ų47.57%0.07325%0.248CC..G310 helixtrans-59.3-22.4176.4-64.20000113.8E83 T84 L88 L89 H122 E133E83-V86 WeakPolarHBondContact O-CG2 3.36Å; T84-V86 VanDerWaalsContact C-N 3.29Å; T84-V86 PolarHBondContact O-N 3.31Å; V86-L88 PolarHBondContact O-N 3.23Å; V86-L89 HydrophobicContact CB-CD1 4.34Å; V86-L89 WeakPolarHBondContact O-CB 3.03Å; V86-L89 WeakPolarHBondContact O-CD1 3.32Å; V86-L89 VanDerWaalsContact O-CG 3.24Å; V86-L89 WeakPolarHBondContact O-CG 3.07Å; V86-L89 PolarHBondContact O-N 3.3Å; V86-H122 HydrophobicContact CG1-CB 3.32Å; V86-E133 HydrophobicContact CG2-CG 4.03Å
87R87.9Confident84.3Confident72 Ų7247.5 Ų47.527%0.27225%0.248SC..G310 helixtrans-71.4-12.5174.2-61.4179.2177.8164.11.9112.7I76 T84 A85 E133I76-R87 HydrophobicContact CD1-CB 4.1Å; T84-R87 WeakPolarHBondContact O-CB 3.39Å; T84-R87 PolarHBondContact O-N 3.42Å; T84-R87 VanDerWaalsContact O-N 3.11Å; A85-R87 PolarHBondContact O-N 3.43Å; A85-R87 VanDerWaalsContact O-N 3.1Å; R87-E133 HydrophobicContact CG-CG 4.42Å; R87-E133 IonicContact NE-OE1 2.66Å
88L92.3Very high85Confident14 Ų1440.9 Ų40.97%0.07322%0.217CC..G310 helixtrans-91.2-1.9175.2-63.1177.3000113.5V46 E73 I76 A85 V86 V90 N91 K92V46-L88 HydrophobicContact CG1-CD2 4.37Å; E73-L88 HydrophobicContact CG-CD2 4.38Å; I76-L88 HydrophobicContact CB-CD1 4.03Å; I76-L88 HydrophobicContact CB-CD2 4.07Å; I76-L88 HydrophobicContact CB-CG 4.08Å; I76-L88 HydrophobicContact CG1-CD1 4.46Å; I76-L88 HydrophobicContact CG1-CD2 3.7Å; I76-L88 HydrophobicContact CG1-CG 3.95Å; I76-L88 HydrophobicContact CG2-CD1 3.84Å; I76-L88 HydrophobicContact CG2-CG 4.03Å; A85-L88 WeakPolarHBondContact O-CB 3.47Å; A85-L88 PolarHBondContact O-N 2.8Å; V86-L88 PolarHBondContact O-N 3.23Å; L88-V90 VanDerWaalsContact C-N 3.33Å; L88-V90 PolarHBondContact O-N 3.37Å; L88-N91 HydrophobicContact CB-CB 4.32Å; L88-N91 HydrophobicContact CD2-CB 3.92Å; L88-N91 WeakPolarHBondContact O-CA 3.48Å; L88-N91 WeakPolarHBondContact O-CB 3.27Å; L88-N91 PolarHBondContact O-N 2.8Å; L88-K92 HydrophobicContact CB-CG 4.25Å; L88-K92 VanDerWaalsContact O-CG 3.31Å; L88-K92 WeakPolarHBondContact O-CG 3.23Å; L88-K92 PolarHBondContact O-N 3.31Å
89L95.1Very high85.9Confident5 Ų534.6 Ų34.63%0.02619%0.187CC..Hα-helixtrans-51.7-50.2178.9-74.2168000112.2V86 N91 A93 L115 L118 Q119 H131 V134V86-L89 HydrophobicContact CB-CD1 4.34Å; V86-L89 WeakPolarHBondContact O-CB 3.03Å; V86-L89 WeakPolarHBondContact O-CD1 3.32Å; V86-L89 VanDerWaalsContact O-CG 3.24Å; V86-L89 WeakPolarHBondContact O-CG 3.07Å; V86-L89 PolarHBondContact O-N 3.3Å; L89-N91 VanDerWaalsContact C-N 3.35Å; L89-A93 PolarHBondContact O-N 2.93Å; L89-L115 HydrophobicContact CB-CD1 4.31Å; L89-L115 HydrophobicContact CD2-CD1 3.7Å; L89-L115 VanDerWaalsContact O-CD1 3.25Å; L89-L115 WeakPolarHBondContact O-CD1 3.41Å; L89-L118 HydrophobicContact CD2-CB 4.31Å; L89-L118 HydrophobicContact CD2-CD2 3.71Å; L89-L118 HydrophobicContact CD2-CG 3.92Å; L89-L118 HydrophobicContact CG-CD2 3.96Å; L89-L118 HydrophobicContact CG-CG 4.49Å; L89-Q119 HydrophobicContact CD2-CG 3.61Å; L89-H131 HydrophobicContact CD1-CB 3.9Å; L89-V134 HydrophobicContact CB-CG2 3.78Å; L89-V134 HydrophobicContact CD1-CG2 3.78Å; L89-V134 HydrophobicContact CG-CG2 4.43Å
90V96.8Very high87.1Confident2 Ų232.3 Ų32.31%0.01218%0.176CC..Hα-helixtrans-69.5-34.2177.5176.50000111.8C14 W18 L88 N94 V134 E137C14-V90 HydrophobicContact CB-CG1 4.29Å; W18-V90 HydrophobicContact CH2-CG1 3.83Å; W18-V90 HydrophobicContact CH2-CG2 3.93Å; W18-V90 HydrophobicContact CZ2-CG1 4.26Å; W18-V90 HydrophobicContact CZ2-CG2 3.97Å; L88-V90 VanDerWaalsContact C-N 3.33Å; L88-V90 PolarHBondContact O-N 3.37Å; V90-N94 WeakPolarHBondContact O-CB 3.25Å; V90-N94 PolarHBondContact O-N 3.12Å; V90-V134 HydrophobicContact CG2-CB 4.47Å; V90-V134 HydrophobicContact CG2-CG1 4.22Å; V90-V134 HydrophobicContact CG2-CG2 4.26Å; V90-E137 VanDerWaalsContact CB-OE2 3.28Å; V90-E137 WeakPolarHBondContact CB-OE2 3.22Å; V90-E137 HydrophobicContact CG1-CG 4.47Å; V90-E137 VanDerWaalsContact CG1-OE1 3.3Å; V90-E137 WeakPolarHBondContact CG1-OE1 3.42Å; V90-E137 HydrophobicContact CG2-CB 4.26Å; V90-E137 HydrophobicContact CG2-CG 4.36Å; V90-E137 WeakPolarHBondContact CG2-OE2 3.4Å
91N96.9Very high89Confident0 Ų034 Ų340%016%0.163CC..Hα-helixtrans-65.6-49.6180176.4-96000112N50 L69 A72 E73 L88 L89 A93 N94 L95N50-N91 WeakPolarHBondContact OD1-CA 3.39Å; N50-N91 VanDerWaalsContact OD1-CB 3.25Å; N50-N91 WeakPolarHBondContact OD1-CB 3.47Å; N50-N91 PolarHBondContact OD1-ND2 3.44Å; L69-N91 PolarHBondContact O-ND2 2.96Å; A72-N91 VanDerWaalsContact CB-ND2 3.32Å; A72-N91 WeakPolarHBondContact CB-ND2 3.42Å; E73-N91 WeakPolarHBondContact CG-OD1 3.16Å; L88-N91 HydrophobicContact CB-CB 4.32Å; L88-N91 HydrophobicContact CD2-CB 3.92Å; L88-N91 WeakPolarHBondContact O-CA 3.48Å; L88-N91 WeakPolarHBondContact O-CB 3.27Å; L88-N91 PolarHBondContact O-N 2.8Å; L89-N91 VanDerWaalsContact C-N 3.35Å; N91-A93 VanDerWaalsContact C-N 3.32Å; N91-A93 PolarHBondContact O-N 3.47Å; N91-N94 WeakPolarHBondContact O-CB 3.4Å; N91-N94 PolarHBondContact O-N 3.05Å; N91-N94 VanDerWaalsContact O-N 3.12Å; N91-L95 PolarHBondContact O-N 2.9Å; N91-L95 VanDerWaalsContact OD1-CD1 3.29Å; N91-L95 WeakPolarHBondContact OD1-CD1 3.3Å
92K97Very high90.5Very high25 Ų2533.3 Ų33.311%0.10916%0.156CC..Hα-helixtrans-61.3-42.1178.5-62.7-70-178.3173.30111E73 L88 N94 L95 A96 Y111 E114 L115E73-K92 WeakPolarHBondContact OE1-CE 3.3Å; E73-K92 IonicContact OE1-NZ 3.27Å; E73-K92 PolarHBondContact OE1-NZ 3.38Å; L88-K92 HydrophobicContact CB-CG 4.25Å; L88-K92 VanDerWaalsContact O-CG 3.31Å; L88-K92 WeakPolarHBondContact O-CG 3.23Å; L88-K92 PolarHBondContact O-N 3.31Å; K92-N94 PolarHBondContact O-N 3.36Å; K92-L95 PolarHBondContact O-N 3.43Å; K92-A96 WeakPolarHBondContact O-CB 3.49Å; K92-A96 PolarHBondContact O-N 3.34Å; K92-Y111 HydrophobicContact CB-CD1 4.46Å; K92-Y111 HydrophobicContact CD-CD1 3.56Å; K92-Y111 HydrophobicContact CD-CE1 3.78Å; K92-E114 WeakPolarHBondContact CE-OE2 3.41Å; K92-E114 IonicContact NZ-OE2 3.3Å; K92-E114 PolarHBondContact NZ-OE2 2.97Å; K92-L115 HydrophobicContact CB-CB 4.32Å; K92-L115 HydrophobicContact CB-CD1 4.23Å
93A98Very high92.2Very high1 Ų128.7 Ų28.71%0.00815%0.15CC..Hα-helixtrans-62-41.5173.100000112.9L12 C14 L89 N91 A96 W97 L115L12-A93 HydrophobicContact CB-CB 4.08Å; L12-A93 HydrophobicContact CD1-CB 3.94Å; C14-A93 HydrophobicContact CB-CB 3.59Å; L89-A93 PolarHBondContact O-N 2.93Å; N91-A93 VanDerWaalsContact C-N 3.32Å; N91-A93 PolarHBondContact O-N 3.47Å; A93-A96 PolarHBondContact O-N 3.47Å; A93-W97 PolarHBondContact O-N 2.92Å; A93-L115 HydrophobicContact CB-CD2 3.91Å
94N98.4Very high93.9Very high0 Ų024.5 Ų24.50%013%0.13CC..Hα-helixtrans-62.5-43.9173.1-83.4-17.5000111.8C14 H15 F16 N50 L69 V90 N91 K92 W97 V98C14-N94 WeakPolarHBondContact CB-OD1 3.49Å; H15-N94 PolarHBondContact N-OD1 2.99Å; H15-N94 VanDerWaalsContact N-OD1 3.14Å; H15-N94 PolarHBondContact ND1-ND2 2.89Å; H15-N94 VanDerWaalsContact ND1-ND2 3.13Å; F16-N94 WeakPolarHBondContact CD2-OD1 3.43Å; F16-N94 HydrophobicContact CE2-CB 4.2Å; N50-N94 PolarHBondContact O-ND2 3.46Å; L69-N94 HydrophobicContact CD1-CB 4Å; L69-N94 HydrophobicContact CD2-CB 3.8Å; V90-N94 WeakPolarHBondContact O-CB 3.25Å; V90-N94 PolarHBondContact O-N 3.12Å; N91-N94 WeakPolarHBondContact O-CB 3.4Å; N91-N94 PolarHBondContact O-N 3.05Å; N91-N94 VanDerWaalsContact O-N 3.12Å; K92-N94 PolarHBondContact O-N 3.36Å; N94-W97 PolarHBondContact O-N 3.5Å; N94-V98 WeakPolarHBondContact O-CG2 3.43Å; N94-V98 PolarHBondContact O-N 3.47Å
95L98.1Very high94.9Very high0 Ų025.7 Ų25.70%014%0.136CC..Hα-helixtrans-62.2-43.1177.7-77.8163.8000111.4L66 L69 E73 N91 K92 W97 V98 Y99 Y111L66-L95 HydrophobicContact CD2-CD2 4.02Å; L69-L95 HydrophobicContact CB-CD1 4.45Å; L69-L95 HydrophobicContact CB-CD2 3.53Å; L69-L95 HydrophobicContact CB-CG 3.87Å; L69-L95 HydrophobicContact CD1-CD2 3.88Å; L69-L95 HydrophobicContact CD1-CG 4.07Å; L69-L95 HydrophobicContact CG-CD2 4.36Å; E73-L95 VanDerWaalsContact CD-CD1 3.45Å; E73-L95 HydrophobicContact CG-CD1 4.09Å; E73-L95 WeakPolarHBondContact OE2-CD1 3.28Å; N91-L95 PolarHBondContact O-N 2.9Å; N91-L95 VanDerWaalsContact OD1-CD1 3.29Å; N91-L95 WeakPolarHBondContact OD1-CD1 3.3Å; K92-L95 PolarHBondContact O-N 3.43Å; L95-W97 VanDerWaalsContact C-N 3.3Å; L95-W97 PolarHBondContact O-N 3.47Å; L95-V98 PolarHBondContact O-N 3.11Å; L95-Y99 HydrophobicContact CB-CD2 4.49Å; L95-Y99 HydrophobicContact CD2-CE2 4.09Å; L95-Y99 VanDerWaalsContact O-CD2 3.24Å; L95-Y99 WeakPolarHBondContact O-CD2 3.47Å; L95-Y99 PolarHBondContact O-N 2.95Å; L95-Y111 HydrophobicContact CB-CD1 3.81Å; L95-Y111 HydrophobicContact CB-CD2 4.06Å; L95-Y111 HydrophobicContact CB-CE1 3.89Å; L95-Y111 HydrophobicContact CB-CE2 4.19Å; L95-Y111 HydrophobicContact CB-CG 3.88Å; L95-Y111 HydrophobicContact CD1-CD1 4.03Å; L95-Y111 HydrophobicContact CD1-CE1 3.38Å; L95-Y111 HydrophobicContact CG-CE1 4.19Å
96A98Very high95.7Very high0 Ų031.2 Ų31.20%016%0.157CC..Hα-helixtrans-56.3-44.8175.200000111.6L9 L12 K92 A93 F100 S108L9-A96 HydrophobicContact CD2-CB 3.64Å; L12-A96 HydrophobicContact CD1-CB 4.47Å; K92-A96 WeakPolarHBondContact O-CB 3.49Å; K92-A96 PolarHBondContact O-N 3.34Å; A93-A96 PolarHBondContact O-N 3.47Å; A96-F100 WeakPolarHBondContact O-CB 3.4Å; A96-F100 PolarHBondContact O-N 2.61Å; A96-S108 WeakPolarHBondContact O-CB 3.45Å; A96-S108 PolarHBondContact O-OG 3.42Å
97W97.9Very high96.2Very high10 Ų1035.3 Ų35.34%0.03817%0.174CC..Hα-helixtrans-64.6-44.6174.2-91.5103.9000113.4L9 E10 F16 T17 A93 N94 L95 F100 Y101L9-W97 HydrophobicContact CB-CD2 4.1Å; L9-W97 HydrophobicContact CB-CH2 4.22Å; L9-W97 HydrophobicContact CB-CZ2 3.69Å; L9-W97 HydrophobicContact CD1-CD2 4.44Å; L9-W97 HydrophobicContact CD1-CE3 4.43Å; L9-W97 PolarHBondContact O-NE1 2.93Å; E10-W97 HydrophobicContact CG-CH2 4.01Å; E10-W97 HydrophobicContact CG-CZ2 4.02Å; F16-W97 HydrophobicContact CB-CB 4.28Å; F16-W97 HydrophobicContact CB-CD2 3.92Å; F16-W97 HydrophobicContact CB-CG 3.77Å; F16-W97 HydrophobicContact CD2-CB 3.49Å; F16-W97 VanDerWaalsContact CD2-CB 3.49Å; F16-W97 AromaticContact CD2-CG 3.88Å; F16-W97 HydrophobicContact CD2-CG 3.88Å; F16-W97 HydrophobicContact CE2-CB 3.92Å; F16-W97 HydrophobicContact CG-CB 3.88Å; F16-W97 HydrophobicContact CG-CD2 4.35Å; F16-W97 AromaticContact CG-CG 3.92Å; F16-W97 HydrophobicContact CG-CG 3.92Å; T17-W97 HydrophobicContact CG2-CZ2 4.04Å; A93-W97 PolarHBondContact O-N 2.92Å; N94-W97 PolarHBondContact O-N 3.5Å; L95-W97 VanDerWaalsContact C-N 3.3Å; L95-W97 PolarHBondContact O-N 3.47Å; W97-F100 HydrophobicContact CE3-CD1 4.31Å; W97-F100 HydrophobicContact CZ3-CD1 4.29Å; W97-F100 WeakPolarHBondContact O-CB 3.17Å; W97-F100 PolarHBondContact O-N 3.27Å; W97-Y101 HydrophobicContact CB-CE2 4.35Å; W97-Y101 HydrophobicContact CD2-CE2 4.31Å; W97-Y101 HydrophobicContact CE3-CD2 4.3Å; W97-Y101 HydrophobicContact CE3-CE1 4.2Å; W97-Y101 AromaticContact CE3-CE2 3.48Å; W97-Y101 HydrophobicContact CE3-CE2 3.48Å; W97-Y101 VanDerWaalsContact CE3-CE2 3.48Å; W97-Y101 AromaticContact CE3-CZ 3.42Å; W97-Y101 VanDerWaalsContact CE3-CZ 3.42Å; W97-Y101 HydrophobicContact CZ3-CE1 4.13Å; W97-Y101 HydrophobicContact CZ3-CE2 4.15Å; W97-Y101 AromaticContact CZ3-CZ 3.59Å; W97-Y101 WeakPolarHBondContact CZ3-OH 3.48Å; W97-Y101 WeakPolarHBondContact O-CD2 3.34Å; W97-Y101 PolarHBondContact O-N 3.15Å
98V97.6Very high96.7Very high0 Ų031.9 Ų31.90%016%0.161CC..Hα-helixtrans-64.6-45.8-179.1173.50000111.1F16 K57 L66 L69 N94 L95 F100 Y101 L102F16-V98 HydrophobicContact CE2-CG2 3.94Å; F16-V98 HydrophobicContact CZ-CG2 3.74Å; K57-V98 HydrophobicContact CB-CG2 4.4Å; K57-V98 HydrophobicContact CG-CG2 4.26Å; L66-V98 HydrophobicContact CD2-CB 4.28Å; L66-V98 HydrophobicContact CD2-CG1 3.53Å; L66-V98 HydrophobicContact CG-CG1 3.8Å; L69-V98 HydrophobicContact CD1-CB 4.31Å; L69-V98 HydrophobicContact CD1-CG2 3.67Å; N94-V98 WeakPolarHBondContact O-CG2 3.43Å; N94-V98 PolarHBondContact O-N 3.47Å; L95-V98 PolarHBondContact O-N 3.11Å; V98-F100 VanDerWaalsContact C-N 3.31Å; V98-F100 PolarHBondContact O-N 3.33Å; V98-Y101 PolarHBondContact O-N 3.5Å; V98-L102 HydrophobicContact CG1-CD1 4.09Å; V98-L102 WeakPolarHBondContact O-CG 3.26Å; V98-L102 PolarHBondContact O-N 3.06Å
99Y97.7Very high96.9Very high13 Ų1333.5 Ų33.55%0.05117%0.166CC..Hα-helixtrans-64.6-35.3176-77.6-62.7000112.6L66 L95 L102 G103 E104 K107 Y111L66-Y99 HydrophobicContact CD1-CE1 4.14Å; L66-Y99 HydrophobicContact CD2-CD1 4.48Å; L66-Y99 HydrophobicContact CD2-CD2 4.44Å; L66-Y99 HydrophobicContact CD2-CE1 4.02Å; L66-Y99 HydrophobicContact CD2-CE2 3.93Å; L95-Y99 HydrophobicContact CB-CD2 4.49Å; L95-Y99 HydrophobicContact CD2-CE2 4.09Å; L95-Y99 VanDerWaalsContact O-CD2 3.24Å; L95-Y99 WeakPolarHBondContact O-CD2 3.47Å; L95-Y99 PolarHBondContact O-N 2.95Å; Y99-L102 HydrophobicContact CD1-CD1 4.39Å; Y99-L102 PolarHBondContact O-N 3.36Å; Y99-G103 PolarHBondContact O-N 3.47Å; Y99-E104 HydrophobicContact CD1-CB 3.9Å; Y99-E104 HydrophobicContact CD1-CG 4.43Å; Y99-E104 PolarHBondContact O-N 2.92Å; Y99-K107 HydrophobicContact CD1-CB 3.88Å; Y99-K107 HydrophobicContact CD1-CD 3.71Å; Y99-K107 HydrophobicContact CD1-CG 4.45Å; Y99-K107 HydrophobicContact CD2-CB 4.06Å; Y99-K107 HydrophobicContact CE1-CB 4.27Å; Y99-K107 HydrophobicContact CE1-CD 3.37Å; Y99-K107 HydrophobicContact CE1-CG 4.49Å; Y99-K107 HydrophobicContact CE2-CB 4.46Å; Y99-K107 HydrophobicContact CE2-CD 4.46Å; Y99-K107 HydrophobicContact CG-CB 3.74Å; Y99-K107 HydrophobicContact CG-CD 4.35Å; Y99-Y111 AromaticContact CD2-CD2 3.65Å; Y99-Y111 HydrophobicContact CD2-CD2 3.65Å; Y99-Y111 AromaticContact CD2-CE2 3.61Å; Y99-Y111 HydrophobicContact CD2-CE2 3.61Å; Y99-Y111 AromaticContact CE2-CD2 3.78Å; Y99-Y111 HydrophobicContact CE2-CD2 3.78Å; Y99-Y111 AromaticContact CE2-CE2 3.2Å; Y99-Y111 HydrophobicContact CE2-CE2 3.2Å
100F96.9Very high97Very high33 Ų3334.4 Ų34.415%0.14518%0.176CC..Hα-helixtrans-59.3-48171.5177.6-97.1000111.7L5 K6 L9 A96 W97 V98 L102 G103 L105L5-F100 HydrophobicContact CD2-CD2 3.9Å; L5-F100 HydrophobicContact CD2-CE2 4.39Å; L5-F100 HydrophobicContact CG-CD2 4.16Å; L5-F100 HydrophobicContact CG-CE2 4.47Å; K6-F100 HydrophobicContact CB-CE1 4.41Å; K6-F100 HydrophobicContact CB-CE2 4.19Å; K6-F100 HydrophobicContact CB-CZ 3.75Å; K6-F100 HydrophobicContact CD-CE1 4.43Å; K6-F100 HydrophobicContact CD-CZ 4.26Å; K6-F100 HydrophobicContact CG-CE1 4.28Å; K6-F100 HydrophobicContact CG-CZ 4.08Å; L9-F100 HydrophobicContact CD1-CB 3.5Å; L9-F100 VanDerWaalsContact CD1-CB 3.5Å; L9-F100 HydrophobicContact CD1-CD1 4.06Å; L9-F100 HydrophobicContact CD1-CD2 3.69Å; L9-F100 HydrophobicContact CD1-CE2 4.45Å; L9-F100 HydrophobicContact CD1-CG 3.46Å; L9-F100 VanDerWaalsContact CD1-CG 3.46Å; A96-F100 WeakPolarHBondContact O-CB 3.4Å; A96-F100 PolarHBondContact O-N 2.61Å; W97-F100 HydrophobicContact CE3-CD1 4.31Å; W97-F100 HydrophobicContact CZ3-CD1 4.29Å; W97-F100 WeakPolarHBondContact O-CB 3.17Å; W97-F100 PolarHBondContact O-N 3.27Å; V98-F100 VanDerWaalsContact C-N 3.31Å; V98-F100 PolarHBondContact O-N 3.33Å; F100-L102 PolarHBondContact O-N 2.97Å; F100-G103 PolarHBondContact O-N 3.27Å; F100-L105 HydrophobicContact CD2-CD2 3.87Å; F100-L105 HydrophobicContact CE2-CD2 4.19Å
101Y94.7Very high97.1Very high100 Ų10035.8 Ų35.839%0.39218%0.182SC..Hα-helixtrans-64.7-23.9177.4-71.4-54.4000113.9F16 K57 W97 V98 G103F16-Y101 AromaticContact CD1-CE2 3.75Å; F16-Y101 HydrophobicContact CD1-CE2 3.75Å; F16-Y101 HydrophobicContact CE1-CD2 4.4Å; F16-Y101 AromaticContact CE1-CE2 3.87Å; F16-Y101 HydrophobicContact CE1-CE2 3.87Å; F16-Y101 HydrophobicContact CG-CE2 4.42Å; K57-Y101 HydrophobicContact CG-CD2 4.47Å; W97-Y101 HydrophobicContact CB-CE2 4.35Å; W97-Y101 HydrophobicContact CD2-CE2 4.31Å; W97-Y101 HydrophobicContact CE3-CD2 4.3Å; W97-Y101 HydrophobicContact CE3-CE1 4.2Å; W97-Y101 AromaticContact CE3-CE2 3.48Å; W97-Y101 HydrophobicContact CE3-CE2 3.48Å; W97-Y101 VanDerWaalsContact CE3-CE2 3.48Å; W97-Y101 AromaticContact CE3-CZ 3.42Å; W97-Y101 VanDerWaalsContact CE3-CZ 3.42Å; W97-Y101 HydrophobicContact CZ3-CE1 4.13Å; W97-Y101 HydrophobicContact CZ3-CE2 4.15Å; W97-Y101 AromaticContact CZ3-CZ 3.59Å; W97-Y101 WeakPolarHBondContact CZ3-OH 3.48Å; W97-Y101 WeakPolarHBondContact O-CD2 3.34Å; W97-Y101 PolarHBondContact O-N 3.15Å; V98-Y101 PolarHBondContact O-N 3.5Å; Y101-G103 VanDerWaalsContact C-N 3.31Å
102L94.8Very high97Very high58 Ų5836.3 Ų36.330%0.30418%0.184SC..THydrogen-bonded Turntrans-82.7-7.1175-72.3172.9000113.5D62 L66 V98 Y99 F100 E104D62-L102 HydrophobicContact CB-CD2 3.91Å; D62-L102 VanDerWaalsContact OD2-CD2 3.3Å; D62-L102 WeakPolarHBondContact OD2-CD2 3.47Å; L66-L102 HydrophobicContact CD1-CD1 3.57Å; L66-L102 HydrophobicContact CG-CD1 4.19Å; V98-L102 HydrophobicContact CG1-CD1 4.09Å; V98-L102 WeakPolarHBondContact O-CG 3.26Å; V98-L102 PolarHBondContact O-N 3.06Å; Y99-L102 HydrophobicContact CD1-CD1 4.39Å; Y99-L102 PolarHBondContact O-N 3.36Å; F100-L102 PolarHBondContact O-N 2.97Å; L102-E104 HydrophobicContact CB-CG 4.28Å; L102-E104 PolarHBondContact O-N 3.39Å
103G95Very high97Very high56 Ų5641.2 Ų41.258%0.57721%0.208SC*.THydrogen-bonded Turntrans77.28.1-173.700000113.8Y99 F100 Y101 L105Y99-G103 PolarHBondContact O-N 3.47Å; F100-G103 PolarHBondContact O-N 3.27Å; Y101-G103 VanDerWaalsContact C-N 3.31Å; G103-L105 VanDerWaalsContact C-N 3.26Å; G103-L105 PolarHBondContact O-N 3.36Å
104E96.7Very high96.9Very high72 Ų7245.6 Ų45.634%0.33623%0.228SC..  trans-86.665.5177.6-63.9-166.6-129.700110.5Y99 L102 E106 K107 S108Y99-E104 HydrophobicContact CD1-CB 3.9Å; Y99-E104 HydrophobicContact CD1-CG 4.43Å; Y99-E104 PolarHBondContact O-N 2.92Å; L102-E104 HydrophobicContact CB-CG 4.28Å; L102-E104 PolarHBondContact O-N 3.39Å; E104-E106 VanDerWaalsContact C-N 3.31Å; E104-E106 PolarHBondContact O-N 2.76Å; E104-K107 HydrophobicContact CB-CB 4.39Å; E104-K107 HydrophobicContact CB-CD 4.5Å; E104-K107 PolarHBondContact O-N 3.47Å; E104-K107 VanDerWaalsContact O-N 3.15Å; E104-K107 WeakPolarHBondContact OE2-CD 3.43Å; E104-K107 WeakPolarHBondContact OE2-CE 3.34Å; E104-K107 IonicContact OE2-NZ 3.38Å; E104-K107 PolarHBondContact OE2-NZ 2.94Å; E104-S108 PolarHBondContact O-N 3.19Å
105L96.7Very high96.7Very high40 Ų4045.7 Ų45.721%0.20923%0.229CC..Hα-helixtrans-60.9-36-169-55.2-176.6000113.6D2 L5 F100 G103 S108 R109D2-L105 VanDerWaalsContact OD1-CD1 3.24Å; D2-L105 WeakPolarHBondContact OD1-CD1 3.24Å; L5-L105 HydrophobicContact CD2-CB 4.42Å; L5-L105 HydrophobicContact CD2-CD2 4.24Å; F100-L105 HydrophobicContact CD2-CD2 3.87Å; F100-L105 HydrophobicContact CE2-CD2 4.19Å; G103-L105 VanDerWaalsContact C-N 3.26Å; G103-L105 PolarHBondContact O-N 3.36Å; L105-S108 WeakPolarHBondContact O-CB 3.25Å; L105-S108 PolarHBondContact O-N 3.45Å; L105-R109 WeakPolarHBondContact O-CG 3.42Å; L105-R109 PolarHBondContact O-N 2.79Å
106E96.9Very high96.5Very high143 Ų14350.8 Ų50.867%0.66825%0.252SS*.Hα-helixtrans-65-40.4177.8-64-52.4134.500112E104 R109 G110E104-E106 VanDerWaalsContact C-N 3.31Å; E104-E106 PolarHBondContact O-N 2.76Å; E106-R109 PolarHBondContact O-N 3Å; E106-G110 PolarHBondContact O-N 2.93Å
107K97.2Very high96.3Very high98 Ų9854.6 Ų54.643%0.42627%0.27SS..Hα-helixtrans-67.4-40.6174.1-67.4-171-172.9163.30111.2Y99 E104 R109 G110 Y111Y99-K107 HydrophobicContact CD1-CB 3.88Å; Y99-K107 HydrophobicContact CD1-CD 3.71Å; Y99-K107 HydrophobicContact CD1-CG 4.45Å; Y99-K107 HydrophobicContact CD2-CB 4.06Å; Y99-K107 HydrophobicContact CE1-CB 4.27Å; Y99-K107 HydrophobicContact CE1-CD 3.37Å; Y99-K107 HydrophobicContact CE1-CG 4.49Å; Y99-K107 HydrophobicContact CE2-CB 4.46Å; Y99-K107 HydrophobicContact CE2-CD 4.46Å; Y99-K107 HydrophobicContact CG-CB 3.74Å; Y99-K107 HydrophobicContact CG-CD 4.35Å; E104-K107 HydrophobicContact CB-CB 4.39Å; E104-K107 HydrophobicContact CB-CD 4.5Å; E104-K107 PolarHBondContact O-N 3.47Å; E104-K107 VanDerWaalsContact O-N 3.15Å; E104-K107 WeakPolarHBondContact OE2-CD 3.43Å; E104-K107 WeakPolarHBondContact OE2-CE 3.34Å; E104-K107 IonicContact OE2-NZ 3.38Å; E104-K107 PolarHBondContact OE2-NZ 2.94Å; K107-R109 VanDerWaalsContact C-N 3.3Å; K107-R109 PolarHBondContact O-N 3.38Å; K107-G110 PolarHBondContact O-N 3.31Å; K107-Y111 VanDerWaalsContact O-CD2 3.28Å; K107-Y111 WeakPolarHBondContact O-CD2 3.11Å; K107-Y111 PolarHBondContact O-N 3.17Å
108S97.7Very high96Very high0 Ų055.2 Ų55.20%027%0.274CS..Hα-helixtrans-56.7-44175.2-1760000111.9A96 E104 L105 Y111 L112A96-S108 WeakPolarHBondContact O-CB 3.45Å; A96-S108 PolarHBondContact O-OG 3.42Å; E104-S108 PolarHBondContact O-N 3.19Å; L105-S108 WeakPolarHBondContact O-CB 3.25Å; L105-S108 PolarHBondContact O-N 3.45Å; S108-Y111 PolarHBondContact O-N 3.14Å; S108-L112 PolarHBondContact O-N 2.98Å; S108-L112 VanDerWaalsContact O-N 3.14Å
109R96.9Very high95.8Very high47 Ų4759.7 Ų59.718%0.17730%0.295CS..Hα-helixtrans-63.7-45.3173.5-70.6-177.7-158.9-64.2-12.8112.6L5 L105 E106 K107 Y111 L112 E113L5-R109 HydrophobicContact CD1-CG 4.15Å; L5-R109 HydrophobicContact CD2-CG 4.25Å; L105-R109 WeakPolarHBondContact O-CG 3.42Å; L105-R109 PolarHBondContact O-N 2.79Å; E106-R109 PolarHBondContact O-N 3Å; K107-R109 VanDerWaalsContact C-N 3.3Å; K107-R109 PolarHBondContact O-N 3.38Å; R109-Y111 VanDerWaalsContact C-N 3.29Å; R109-Y111 PolarHBondContact O-N 3.32Å; R109-L112 WeakPolarHBondContact O-CA 3.38Å; R109-L112 WeakPolarHBondContact O-CB 3.27Å; R109-L112 PolarHBondContact O-N 3.17Å; R109-E113 WeakPolarHBondContact O-CG 3.39Å; R109-E113 PolarHBondContact O-N 3.03Å
110G97.8Very high95.5Very high24 Ų2466.9 Ų66.925%0.24732%0.322CS..Hα-helixtrans-55.6-44.2177.900000112.4E106 K107 L112 E113 E114E106-G110 PolarHBondContact O-N 2.93Å; K107-G110 PolarHBondContact O-N 3.31Å; G110-L112 VanDerWaalsContact C-N 3.33Å; G110-L112 PolarHBondContact O-N 2.87Å; G110-E113 PolarHBondContact O-N 3.41Å; G110-E114 WeakPolarHBondContact O-CG 3.44Å; G110-E114 PolarHBondContact O-N 3.46Å
111Y97.5Very high95.3Very high32 Ų3269 Ų6913%0.12533%0.334CS..Hα-helixtrans-68.2-29.9175.4-81.4-73.4000113.9E73 K92 L95 Y99 K107 S108 R109 L115E73-Y111 PolarHBondContact OE2-OH 2.97Å; K92-Y111 HydrophobicContact CB-CD1 4.46Å; K92-Y111 HydrophobicContact CD-CD1 3.56Å; K92-Y111 HydrophobicContact CD-CE1 3.78Å; L95-Y111 HydrophobicContact CB-CD1 3.81Å; L95-Y111 HydrophobicContact CB-CD2 4.06Å; L95-Y111 HydrophobicContact CB-CE1 3.89Å; L95-Y111 HydrophobicContact CB-CE2 4.19Å; L95-Y111 HydrophobicContact CB-CG 3.88Å; L95-Y111 HydrophobicContact CD1-CD1 4.03Å; L95-Y111 HydrophobicContact CD1-CE1 3.38Å; L95-Y111 HydrophobicContact CG-CE1 4.19Å; Y99-Y111 AromaticContact CD2-CD2 3.65Å; Y99-Y111 HydrophobicContact CD2-CD2 3.65Å; Y99-Y111 AromaticContact CD2-CE2 3.61Å; Y99-Y111 HydrophobicContact CD2-CE2 3.61Å; Y99-Y111 AromaticContact CE2-CD2 3.78Å; Y99-Y111 HydrophobicContact CE2-CD2 3.78Å; Y99-Y111 AromaticContact CE2-CE2 3.2Å; Y99-Y111 HydrophobicContact CE2-CE2 3.2Å; K107-Y111 VanDerWaalsContact O-CD2 3.28Å; K107-Y111 WeakPolarHBondContact O-CD2 3.11Å; K107-Y111 PolarHBondContact O-N 3.17Å; S108-Y111 PolarHBondContact O-N 3.14Å; R109-Y111 VanDerWaalsContact C-N 3.29Å; R109-Y111 PolarHBondContact O-N 3.32Å; Y111-L115 WeakPolarHBondContact O-CB 3.24Å; Y111-L115 PolarHBondContact O-N 3.35Å
112L96.6Very high95Very high11 Ų1166.5 Ų66.56%0.05833%0.326CS..Hα-helixtrans-68-45.7173.4-176.265.4000110.9L5 E8 L12 S108 R109 G110 L115 E116L5-L112 HydrophobicContact CD1-CD2 4.07Å; E8-L112 HydrophobicContact CB-CD2 4.03Å; L12-L112 HydrophobicContact CD1-CD1 4.05Å; L12-L112 HydrophobicContact CD2-CD1 3.85Å; L12-L112 HydrophobicContact CG-CD1 4.41Å; S108-L112 PolarHBondContact O-N 2.98Å; S108-L112 VanDerWaalsContact O-N 3.14Å; R109-L112 WeakPolarHBondContact O-CA 3.38Å; R109-L112 WeakPolarHBondContact O-CB 3.27Å; R109-L112 PolarHBondContact O-N 3.17Å; G110-L112 VanDerWaalsContact C-N 3.33Å; G110-L112 PolarHBondContact O-N 2.87Å; L112-L115 WeakPolarHBondContact O-CB 3.2Å; L112-L115 PolarHBondContact O-N 3.45Å; L112-E116 WeakPolarHBondContact O-CG 3.22Å; L112-E116 PolarHBondContact O-N 3.32Å
113E96.6Very high94.9Very high128 Ų12867.9 Ų67.960%0.59834%0.338SS*.Hα-helixtrans-61.6-43.9176.2-69.3172.3-172.300111.5R109 G110 L115 E116 E117R109-E113 WeakPolarHBondContact O-CG 3.39Å; R109-E113 PolarHBondContact O-N 3.03Å; G110-E113 PolarHBondContact O-N 3.41Å; E113-L115 VanDerWaalsContact C-N 3.3Å; E113-L115 PolarHBondContact O-N 2.92Å; E113-E116 PolarHBondContact O-N 3.47Å; E113-E117 WeakPolarHBondContact O-CB 3.15Å; E113-E117 PolarHBondContact O-N 2.93Å
114E94.9Very high94.7Very high92 Ų9267.1 Ų67.143%0.4333%0.326SS..Hα-helixtrans-60.2-39.5174-75.6-178.9-14500112.3K92 G110 L118K92-E114 WeakPolarHBondContact CE-OE2 3.41Å; K92-E114 IonicContact NZ-OE2 3.3Å; K92-E114 PolarHBondContact NZ-OE2 2.97Å; G110-E114 WeakPolarHBondContact O-CG 3.44Å; G110-E114 PolarHBondContact O-N 3.46Å; E114-L118 VanDerWaalsContact O-CB 3.31Å; E114-L118 WeakPolarHBondContact O-CB 3.41Å; E114-L118 PolarHBondContact O-N 3.46Å
115L94.4Very high94.4Very high3 Ų365.6 Ų65.62%0.01632%0.323CS..Hα-helixtrans-67.4-43.9177.9-179.668.4000111.7L12 L89 K92 A93 Y111 L112 E113 E117 L118 Q119L12-L115 HydrophobicContact CD1-CD2 4.01Å; L12-L115 HydrophobicContact CD2-CD2 3.59Å; L12-L115 HydrophobicContact CG-CD2 4.32Å; L89-L115 HydrophobicContact CB-CD1 4.31Å; L89-L115 HydrophobicContact CD2-CD1 3.7Å; L89-L115 VanDerWaalsContact O-CD1 3.25Å; L89-L115 WeakPolarHBondContact O-CD1 3.41Å; K92-L115 HydrophobicContact CB-CB 4.32Å; K92-L115 HydrophobicContact CB-CD1 4.23Å; A93-L115 HydrophobicContact CB-CD2 3.91Å; Y111-L115 WeakPolarHBondContact O-CB 3.24Å; Y111-L115 PolarHBondContact O-N 3.35Å; L112-L115 WeakPolarHBondContact O-CB 3.2Å; L112-L115 PolarHBondContact O-N 3.45Å; E113-L115 VanDerWaalsContact C-N 3.3Å; E113-L115 PolarHBondContact O-N 2.92Å; L115-E117 VanDerWaalsContact C-N 3.35Å; L115-L118 PolarHBondContact O-N 3.46Å; L115-Q119 WeakPolarHBondContact O-CB 3.41Å; L115-Q119 WeakPolarHBondContact O-CG 3.43Å; L115-Q119 PolarHBondContact O-N 3.35Å
116E94.3Very high94Very high107 Ų10770.2 Ų70.250%0.536%0.355SS..Hα-helixtrans-61-44.3177.2-74.3179.1179.600111.3L112 E113 Q119 R120L112-E116 WeakPolarHBondContact O-CG 3.22Å; L112-E116 PolarHBondContact O-N 3.32Å; E113-E116 PolarHBondContact O-N 3.47Å; E116-Q119 PolarHBondContact O-N 2.95Å; E116-R120 WeakPolarHBondContact O-CB 3.33Å; E116-R120 PolarHBondContact O-N 3.22Å
117E94Very high93.3Very high80 Ų8067.6 Ų67.637%0.37437%0.366SS..Hα-helixtrans-63.5-43.9176.1179.159.1-170.900111.5E113 L115 Q119 R120 I121E113-E117 WeakPolarHBondContact O-CB 3.15Å; E113-E117 PolarHBondContact O-N 2.93Å; L115-E117 VanDerWaalsContact C-N 3.35Å; E117-Q119 VanDerWaalsContact C-N 3.34Å; E117-Q119 PolarHBondContact O-N 3.18Å; E117-R120 WeakPolarHBondContact O-CB 3.44Å; E117-R120 PolarHBondContact O-N 2.85Å; E117-R120 VanDerWaalsContact O-N 3.12Å; E117-R120 IonicContact OE1-CZ 3.22Å; E117-R120 IonicContact OE1-NE 3.79Å; E117-R120 IonicContact OE1-NH2 2.76Å; E117-R120 PolarHBondContact OE1-NH2 2.93Å; E117-R120 IonicContact OE2-CZ 3.47Å; E117-R120 IonicContact OE2-NE 3.39Å; E117-R120 PolarHBondContact OE2-NE 2.78Å; E117-R120 IonicContact OE2-NH2 2.78Å; E117-R120 PolarHBondContact OE2-NH2 2.73Å; E117-I121 HydrophobicContact CG-CD1 4.03Å; E117-I121 WeakPolarHBondContact O-CG1 3.28Å; E117-I121 PolarHBondContact O-N 2.93Å
118L91.6Very high92.8Very high22 Ų2264 Ų6412%0.11535%0.353CS..Hα-helixtrans-62.8-40.2178.1-172.366.1000112A85 L89 E114 L115 R120 I121 H122A85-L118 HydrophobicContact CB-CD1 3.77Å; A85-L118 WeakPolarHBondContact O-CD2 3.38Å; L89-L118 HydrophobicContact CD2-CB 4.31Å; L89-L118 HydrophobicContact CD2-CD2 3.71Å; L89-L118 HydrophobicContact CD2-CG 3.92Å; L89-L118 HydrophobicContact CG-CD2 3.96Å; L89-L118 HydrophobicContact CG-CG 4.49Å; E114-L118 VanDerWaalsContact O-CB 3.31Å; E114-L118 WeakPolarHBondContact O-CB 3.41Å; E114-L118 PolarHBondContact O-N 3.46Å; L115-L118 PolarHBondContact O-N 3.46Å; L118-R120 VanDerWaalsContact C-N 3.32Å; L118-I121 PolarHBondContact O-N 3.48Å; L118-H122 PolarHBondContact O-N 3.43Å
119Q92.5Very high92.4Very high94 Ų9468.6 Ų68.644%0.43938%0.383SS..Hα-helixtrans-67.8-31.4174.4-73.5178.8-18.700112.7L89 L115 E116 E117 H122 P123L89-Q119 HydrophobicContact CD2-CG 3.61Å; L115-Q119 WeakPolarHBondContact O-CB 3.41Å; L115-Q119 WeakPolarHBondContact O-CG 3.43Å; L115-Q119 PolarHBondContact O-N 3.35Å; E116-Q119 PolarHBondContact O-N 2.95Å; E117-Q119 VanDerWaalsContact C-N 3.34Å; E117-Q119 PolarHBondContact O-N 3.18Å; Q119-H122 CarbonylContact O-C 3.27Å; Q119-H122 VanDerWaalsContact O-C 3.27Å; Q119-P123 VanDerWaalsContact O-CA 3.24Å; Q119-P123 WeakPolarHBondContact O-CA 3.25Å; Q119-P123 VanDerWaalsContact O-N 3.12Å
120R92.6Very high92.2Very high165 Ų16567.7 Ų67.762%0.62338%0.382SS*.Hα-helixtrans-69.4-40.3175.2-169.7-170.36975.30.7111.7E116 E117 L118E116-R120 WeakPolarHBondContact O-CB 3.33Å; E116-R120 PolarHBondContact O-N 3.22Å; E117-R120 WeakPolarHBondContact O-CB 3.44Å; E117-R120 PolarHBondContact O-N 2.85Å; E117-R120 VanDerWaalsContact O-N 3.12Å; E117-R120 IonicContact OE1-CZ 3.22Å; E117-R120 IonicContact OE1-NE 3.79Å; E117-R120 IonicContact OE1-NH2 2.76Å; E117-R120 PolarHBondContact OE1-NH2 2.93Å; E117-R120 IonicContact OE2-CZ 3.47Å; E117-R120 IonicContact OE2-NE 3.39Å; E117-R120 PolarHBondContact OE2-NE 2.78Å; E117-R120 IonicContact OE2-NH2 2.78Å; E117-R120 PolarHBondContact OE2-NH2 2.73Å; L118-R120 VanDerWaalsContact C-N 3.32Å
121I91.1Very high92Very high78 Ų7868 Ų6840%0.438%0.377SS..Hα-helixtrans-72.4-39.6177.2-62166.6000110.7E117 L118 P123E117-I121 HydrophobicContact CG-CD1 4.03Å; E117-I121 WeakPolarHBondContact O-CG1 3.28Å; E117-I121 PolarHBondContact O-N 2.93Å; L118-I121 PolarHBondContact O-N 3.48Å; I121-P123 VanDerWaalsContact C-CD 3.5Å; I121-P123 WeakPolarHBondContact O-CD 3.44Å
122H89.5Confident91.9Very high47 Ų4766.7 Ų66.722%0.21837%0.372CS..SBendtrans-12373.1-178.3-55.6-78.4000111.5V86 L118 Q119V86-H122 HydrophobicContact CG1-CB 3.32Å; L118-H122 PolarHBondContact O-N 3.43Å; Q119-H122 CarbonylContact O-C 3.27Å; Q119-H122 VanDerWaalsContact O-C 3.27Å
123P91.4Very high91.7Very high86 Ų8666.8 Ų66.856%0.55837%0.372SS*.PPolyproline II helixtrans-66.6158.6-179.928.8-35.5000111.4Q119 I121Q119-P123 VanDerWaalsContact O-CA 3.24Å; Q119-P123 WeakPolarHBondContact O-CA 3.25Å; Q119-P123 VanDerWaalsContact O-N 3.12Å; I121-P123 VanDerWaalsContact C-CD 3.5Å; I121-P123 WeakPolarHBondContact O-CD 3.44Å
124A91.2Very high91.7Very high40 Ų4061.1 Ų61.133%0.33135%0.346SS..PPolyproline II helixtrans-58.2142.1169.800000110.3
125P90.4Very high91.8Very high41 Ų4156.7 Ų56.727%0.26633%0.325SS..PPolyproline II helixtrans-55.3150.8175.9-26.534.6000112.3G127 C128 P132 A163P125-G127 PolarHBondContact O-N 3.24Å; P125-C128 HydrophobicContact CB-CB 4.41Å; P125-C128 WeakPolarHBondContact O-CB 3.27Å; P125-C128 PolarHBondContact O-N 3.35Å; P125-P132 HydrophobicContact CG-CG 3.87Å; P125-A163 HydrophobicContact CB-CB 4.44Å; P125-A163 HydrophobicContact CG-CB 3.95Å
126P87.9Confident91.9Very high137 Ų13756.6 Ų56.689%0.8933%0.325SS*.THydrogen-bonded Turntrans-53.8126.5-179.8-26.334.5000112.5C128P126-C128 VanDerWaalsContact C-N 3.3Å
127G83.8Confident92Very high87 Ų8751.6 Ų51.690%0.89730%0.302SS*.THydrogen-bonded Turntrans85.6-7.8-178.700000115P125P125-G127 PolarHBondContact O-N 3.24Å
128C85.6Confident92.2Very high23 Ų2348.5 Ų48.516%0.15529%0.287CS..  trans-92.8130.7174.4-61.70000110.7P125 P126 L130P125-C128 HydrophobicContact CB-CB 4.41Å; P125-C128 WeakPolarHBondContact O-CB 3.27Å; P125-C128 PolarHBondContact O-N 3.35Å; P126-C128 VanDerWaalsContact C-N 3.3Å; C128-L130 VanDerWaalsContact C-N 3.29Å; C128-L130 PolarHBondContact O-N 3.1Å
129P89Confident92.4Very high96 Ų9647.4 Ų47.462%0.62328%0.281SS*.SBendtrans-73.9-21.517830-34.8000112.9M159P129-M159 HydrophobicContact CG-CE 3.48Å; P129-M159 VanDerWaalsContact CG-CE 3.48Å; P129-M159 HydrophobicContact CG-SD 3.57Å; P129-M159 VanDerWaalsContact CG-SD 3.57Å
130L93.3Very high92.6Very high29 Ų2944.8 Ų44.815%0.15227%0.267CS..SBendtrans-133.2152.3-177.6-63-179.6000110.5E13 C128 S135 Y156 M159E13-L130 HydrophobicContact CG-CD2 3.63Å; C128-L130 VanDerWaalsContact C-N 3.29Å; C128-L130 PolarHBondContact O-N 3.1Å; L130-S135 WeakPolarHBondContact CB-OG 3.44Å; L130-Y156 HydrophobicContact CD1-CD1 4.36Å; L130-Y156 HydrophobicContact CD1-CE1 4.03Å; L130-M159 HydrophobicContact CB-SD 4.23Å; L130-M159 HydrophobicContact CD1-SD 4.46Å; L130-M159 HydrophobicContact CG-SD 4.45Å
131H94.6Very high92.8Very high31 Ų3137 Ų3714%0.14424%0.238CC..  trans-63.2140.3169.2-169.6-84.5000110.2L89 E133 V134 S135L89-H131 HydrophobicContact CD1-CB 3.9Å; H131-E133 VanDerWaalsContact C-N 3.31Å; H131-E133 PolarHBondContact ND1-N 3.43Å; H131-E133 PolarHBondContact O-N 3.05Å; H131-V134 HydrophobicContact CB-CG2 4.2Å; H131-V134 WeakPolarHBondContact O-CB 3.46Å; H131-V134 PolarHBondContact O-N 3.45Å; H131-S135 PolarHBondContact O-N 3.16Å; H131-S135 VanDerWaalsContact O-N 3.09Å
132P94.1Very high93.1Very high3 Ų333.2 Ų33.22%0.01922%0.219CC..Hα-helixtrans-57.4-38.7-173.9-29.338000114.2P125 V134 S135 G136 A163 W170P125-P132 HydrophobicContact CG-CG 3.87Å; P132-V134 VanDerWaalsContact C-N 3.33Å; P132-V134 PolarHBondContact O-N 2.87Å; P132-S135 PolarHBondContact O-N 2.97Å; P132-G136 PolarHBondContact O-N 3.48Å; P132-A163 HydrophobicContact CB-CB 4.11Å; P132-A163 HydrophobicContact CG-CB 3.3Å; P132-W170 HydrophobicContact CB-CH2 3.42Å; P132-W170 VanDerWaalsContact CB-CH2 3.42Å; P132-W170 HydrophobicContact CB-CZ2 4.37Å; P132-W170 HydrophobicContact CB-CZ3 3.77Å
133E93.6Very high93.4Very high13 Ų1331.7 Ų31.76%0.06121%0.213CC..Hα-helixtrans-62.9-36.1175.3-65.9-70.1-170.700112.7V86 R87 H131 G136 E137 R167V86-E133 HydrophobicContact CG2-CG 4.03Å; R87-E133 HydrophobicContact CG-CG 4.42Å; R87-E133 IonicContact NE-OE1 2.66Å; H131-E133 VanDerWaalsContact C-N 3.31Å; H131-E133 PolarHBondContact ND1-N 3.43Å; H131-E133 PolarHBondContact O-N 3.05Å; E133-G136 PolarHBondContact O-N 3.38Å; E133-E137 WeakPolarHBondContact O-CB 3.33Å; E133-E137 PolarHBondContact O-N 3.03Å; E133-R167 IonicContact OE1-CZ 3.15Å; E133-R167 IonicContact OE1-NH1 3.67Å; E133-R167 IonicContact OE1-NH2 2.7Å; E133-R167 PolarHBondContact OE1-NH2 2.64Å; E133-R167 IonicContact OE2-NH2 3.21Å
134V95.9Very high93.5Very high9 Ų933.3 Ų33.36%0.05521%0.211CC..Hα-helixtrans-68.4-44.8175.3178.50000110.4E13 W18 L89 V90 H131 P132 G136 E137 K138E13-V134 HydrophobicContact CB-CG1 3.65Å; E13-V134 HydrophobicContact CG-CG1 4.46Å; W18-V134 HydrophobicContact CZ2-CG1 4.47Å; L89-V134 HydrophobicContact CB-CG2 3.78Å; L89-V134 HydrophobicContact CD1-CG2 3.78Å; L89-V134 HydrophobicContact CG-CG2 4.43Å; V90-V134 HydrophobicContact CG2-CB 4.47Å; V90-V134 HydrophobicContact CG2-CG1 4.22Å; V90-V134 HydrophobicContact CG2-CG2 4.26Å; H131-V134 HydrophobicContact CB-CG2 4.2Å; H131-V134 WeakPolarHBondContact O-CB 3.46Å; H131-V134 PolarHBondContact O-N 3.45Å; P132-V134 VanDerWaalsContact C-N 3.33Å; P132-V134 PolarHBondContact O-N 2.87Å; V134-G136 PolarHBondContact O-N 3.46Å; V134-E137 PolarHBondContact O-N 3.1Å; V134-K138 VanDerWaalsContact O-CB 3.26Å; V134-K138 WeakPolarHBondContact O-CB 3.29Å; V134-K138 PolarHBondContact O-N 3.34Å
135S96.8Very high93.5Very high0 Ų031.6 Ų31.60%020%0.196CC..Hα-helixtrans-60.6-44174.9-67.40000111.9L130 H131 P132 K138 G139 Y156 M159L130-S135 WeakPolarHBondContact CB-OG 3.44Å; H131-S135 PolarHBondContact O-N 3.16Å; H131-S135 VanDerWaalsContact O-N 3.09Å; P132-S135 PolarHBondContact O-N 2.97Å; S135-K138 PolarHBondContact O-N 2.96Å; S135-G139 PolarHBondContact O-N 3.39Å; S135-Y156 WeakPolarHBondContact O-CB 3.38Å; S135-M159 PolarHBondContact OG-SD 3.31Å; S135-M159 VanDerWaalsContact OG-SD 3.39Å
136G95.8Very high93.5Very high0 Ų031.2 Ų31.20%019%0.192CC..Hα-helixtrans-61.5-49.6177.100000112.4P132 E133 V134 G139 W140P132-G136 PolarHBondContact O-N 3.48Å; E133-G136 PolarHBondContact O-N 3.38Å; V134-G136 PolarHBondContact O-N 3.46Å; G136-G139 PolarHBondContact O-N 2.87Å; G136-W140 PolarHBondContact O-N 3.18Å
137E96.7Very high93.5Very high3 Ų327.6 Ų27.61%0.01416%0.162CC..Hα-helixtrans-62.9-43.9177.5-172.3168.8169.100111.6H15 W18 H47 N50 V90 E133 V134 G139 W140 T141H15-E137 IonicContact CE1-OE1 3.56Å; H15-E137 PolarHBondContact CE1-OE1 3.4Å; H15-E137 VanDerWaalsContact CE1-OE1 3.31Å; W18-E137 HydrophobicContact CH2-CB 4.23Å; W18-E137 HydrophobicContact CH2-CG 3.98Å; W18-E137 HydrophobicContact CZ3-CG 4.4Å; H47-E137 HydrophobicContact CB-CG 4.25Å; H47-E137 VanDerWaalsContact CD2-CG 3.49Å; H47-E137 WeakPolarHBondContact CD2-CG 3.47Å; H47-E137 IonicContact CD2-OE1 3.61Å; H47-E137 IonicContact CD2-OE2 2.71Å; H47-E137 PolarHBondContact CD2-OE2 3.17Å; H47-E137 VanDerWaalsContact CD2-OE2 3.23Å; H47-E137 IonicContact NE2-OE2 3.48Å; N50-E137 VanDerWaalsContact CB-OE1 3.26Å; N50-E137 WeakPolarHBondContact CB-OE1 3.03Å; N50-E137 PolarHBondContact ND2-OE1 3.32Å; N50-E137 PolarHBondContact ND2-OE2 2.92Å; V90-E137 VanDerWaalsContact CB-OE2 3.28Å; V90-E137 WeakPolarHBondContact CB-OE2 3.22Å; V90-E137 HydrophobicContact CG1-CG 4.47Å; V90-E137 VanDerWaalsContact CG1-OE1 3.3Å; V90-E137 WeakPolarHBondContact CG1-OE1 3.42Å; V90-E137 HydrophobicContact CG2-CB 4.26Å; V90-E137 HydrophobicContact CG2-CG 4.36Å; V90-E137 WeakPolarHBondContact CG2-OE2 3.4Å; E133-E137 WeakPolarHBondContact O-CB 3.33Å; E133-E137 PolarHBondContact O-N 3.03Å; V134-E137 PolarHBondContact O-N 3.1Å; E137-G139 VanDerWaalsContact C-N 3.35Å; E137-G139 PolarHBondContact O-N 3.07Å; E137-W140 PolarHBondContact O-N 2.97Å; E137-T141 PolarHBondContact O-N 3.31Å; E137-T141 PolarHBondContact O-OG1 3.11Å
138K97.8Very high93.8Very high14 Ų1426.1 Ų26.16%0.06114%0.138CC..Hα-helixtrans-59.1-45.6175.8-169.4166.9-171.3169.80111.6E13 W18 V134 S135 W140 T141 L142 Y156E13-K138 IonicContact OE1-NZ 2.61Å; E13-K138 PolarHBondContact OE1-NZ 2.95Å; E13-K138 IonicContact OE2-NZ 2.99Å; E13-K138 PolarHBondContact OE2-NZ 3.2Å; W18-K138 HydrophobicContact CD2-CB 4.2Å; W18-K138 HydrophobicContact CD2-CD 4.05Å; W18-K138 HydrophobicContact CD2-CG 3.7Å; W18-K138 HydrophobicContact CE3-CB 4.35Å; W18-K138 HydrophobicContact CE3-CG 4.12Å; W18-K138 HydrophobicContact CG-CD 4.1Å; W18-K138 HydrophobicContact CG-CG 4.09Å; W18-K138 VanDerWaalsContact CH2-CA 3.49Å; W18-K138 HydrophobicContact CH2-CB 3.78Å; W18-K138 HydrophobicContact CH2-CG 4.37Å; W18-K138 HydrophobicContact CZ2-CB 3.61Å; W18-K138 HydrophobicContact CZ2-CD 4.19Å; W18-K138 HydrophobicContact CZ2-CG 3.98Å; W18-K138 HydrophobicContact CZ3-CB 4.16Å; W18-K138 HydrophobicContact CZ3-CG 4.44Å; V134-K138 VanDerWaalsContact O-CB 3.26Å; V134-K138 WeakPolarHBondContact O-CB 3.29Å; V134-K138 PolarHBondContact O-N 3.34Å; S135-K138 PolarHBondContact O-N 2.96Å; K138-W140 PolarHBondContact O-N 3.41Å; K138-T141 PolarHBondContact O-N 3.17Å; K138-L142 HydrophobicContact CG-CD1 3.91Å; K138-L142 HydrophobicContact CG-CG 4.4Å; K138-L142 WeakPolarHBondContact O-CB 3.13Å; K138-L142 WeakPolarHBondContact O-CG 3.37Å; K138-L142 PolarHBondContact O-N 2.85Å; K138-Y156 HydrophobicContact CB-CG 4.46Å; K138-Y156 HydrophobicContact CD-CD1 3.99Å; K138-Y156 HydrophobicContact CD-CD2 4.16Å; K138-Y156 HydrophobicContact CD-CE1 3.64Å; K138-Y156 HydrophobicContact CD-CE2 3.79Å; K138-Y156 HydrophobicContact CD-CG 4.25Å; K138-Y156 VanDerWaalsContact CE-OH 3.22Å; K138-Y156 WeakPolarHBondContact CE-OH 3.49Å; K138-Y156 HydrophobicContact CG-CD1 4.45Å; K138-Y156 HydrophobicContact CG-CD2 4.03Å; K138-Y156 HydrophobicContact CG-CE1 4.49Å; K138-Y156 HydrophobicContact CG-CE2 4.03Å; K138-Y156 HydrophobicContact CG-CG 4.24Å; K138-Y156 PolarHBondContact NZ-OH 3.43Å; K138-Y156 VanDerWaalsContact NZ-OH 3.11Å
139G97.4Very high94.2Very high0 Ų025.6 Ų25.60%013%0.133CC..Hα-helixtrans-56.4-48.117400000112.3S135 G136 E137 T141 L142 V143 A153S135-G139 PolarHBondContact O-N 3.39Å; G136-G139 PolarHBondContact O-N 2.87Å; E137-G139 VanDerWaalsContact C-N 3.35Å; E137-G139 PolarHBondContact O-N 3.07Å; G139-T141 PolarHBondContact O-N 3.3Å; G139-L142 PolarHBondContact O-N 3.04Å; G139-V143 PolarHBondContact O-N 3.14Å; G139-A153 WeakPolarHBondContact O-CB 3.24Å
140W96.6Very high94.5Very high38 Ų3822.8 Ų22.814%0.14411%0.111CC..Hα-helixtrans-66.5-35.9179.6-83122.5000114.2G136 E137 K138 V143 K144 F157 E169 K172 I176G136-W140 PolarHBondContact O-N 3.18Å; E137-W140 PolarHBondContact O-N 2.97Å; K138-W140 PolarHBondContact O-N 3.41Å; W140-V143 HydrophobicContact CE3-CG1 3.97Å; W140-V143 HydrophobicContact CZ3-CG1 4.37Å; W140-V143 WeakPolarHBondContact O-CG1 3.3Å; W140-K144 WeakPolarHBondContact O-CE 3.41Å; W140-F157 HydrophobicContact CB-CZ 4.41Å; W140-F157 AromaticContact CD1-CE1 3.84Å; W140-F157 HydrophobicContact CD2-CE1 4.14Å; W140-F157 AromaticContact CD2-CZ 3.8Å; W140-F157 HydrophobicContact CD2-CZ 3.8Å; W140-F157 HydrophobicContact CE3-CZ 4.21Å; W140-F157 HydrophobicContact CG-CE1 4.03Å; W140-F157 AromaticContact CG-CZ 3.87Å; W140-F157 HydrophobicContact CG-CZ 3.87Å; W140-F157 VanDerWaalsContact N-CZ 3.3Å; W140-F157 AromaticContact NE1-CE1 3.9Å; W140-E169 HydrophobicContact CZ2-CG 3.65Å; W140-E169 WeakPolarHBondContact CZ2-O 3.15Å; W140-E169 VanDerWaalsContact NE1-CG 3.33Å; W140-E169 PolarHBondContact NE1-OE1 3.22Å; W140-K172 HydrophobicContact CH2-CB 4.41Å; W140-K172 HydrophobicContact CH2-CD 4.32Å; W140-K172 HydrophobicContact CH2-CG 4.11Å; W140-I176 HydrophobicContact CH2-CD1 4.07Å; W140-I176 HydrophobicContact CZ3-CD1 4.01Å
141T96.9Very high94.5Very high1 Ų124.7 Ų24.71%0.00613%0.126CC..Hα-helixtrans-66.9-51.4174.6-72.60000109.8H15 W18 L20 L51 E137 K138 G139 V143 K144 F145H15-T141 PolarHBondContact NE2-OG1 3.47Å; W18-T141 HydrophobicContact CE3-CG2 3.91Å; W18-T141 HydrophobicContact CZ3-CG2 4.07Å; L20-T141 HydrophobicContact CD1-CG2 3.59Å; L20-T141 HydrophobicContact CD2-CG2 3.77Å; L20-T141 HydrophobicContact CG-CG2 4.35Å; L51-T141 HydrophobicContact CD1-CG2 4.25Å; E137-T141 PolarHBondContact O-N 3.31Å; E137-T141 PolarHBondContact O-OG1 3.11Å; K138-T141 PolarHBondContact O-N 3.17Å; G139-T141 PolarHBondContact O-N 3.3Å; T141-V143 VanDerWaalsContact C-N 3.28Å; T141-V143 PolarHBondContact O-N 3.34Å; T141-K144 WeakPolarHBondContact O-CB 3.38Å; T141-K144 PolarHBondContact O-N 2.94Å; T141-K144 VanDerWaalsContact O-N 3.1Å; T141-F145 HydrophobicContact CG2-CE2 3.96Å; T141-F145 VanDerWaalsContact O-CD2 3.24Å; T141-F145 WeakPolarHBondContact O-CD2 3.32Å
142L97.1Very high94.6Very high0 Ų027 Ų270%014%0.138CC..Hα-helixtrans-60.1-33.7-178.5-70.4172.5000113.4L20 K138 G139 K144 F145 K149 Q152 A153 Y156L20-L142 HydrophobicContact CD2-CD2 3.95Å; K138-L142 HydrophobicContact CG-CD1 3.91Å; K138-L142 HydrophobicContact CG-CG 4.4Å; K138-L142 WeakPolarHBondContact O-CB 3.13Å; K138-L142 WeakPolarHBondContact O-CG 3.37Å; K138-L142 PolarHBondContact O-N 2.85Å; G139-L142 PolarHBondContact O-N 3.04Å; L142-K144 PolarHBondContact O-N 3.37Å; L142-K144 VanDerWaalsContact O-N 3.13Å; L142-F145 PolarHBondContact O-N 3.44Å; L142-F145 VanDerWaalsContact O-N 3.17Å; L142-K149 HydrophobicContact CB-CB 4.4Å; L142-K149 HydrophobicContact CD2-CB 4.01Å; L142-K149 HydrophobicContact CD2-CD 3.53Å; L142-K149 HydrophobicContact CD2-CG 4.24Å; L142-Q152 HydrophobicContact CD1-CB 4.08Å; L142-A153 HydrophobicContact CB-CB 3.85Å; L142-Y156 HydrophobicContact CD1-CD2 3.53Å; L142-Y156 HydrophobicContact CD1-CE2 3.61Å
143V95.4Very high94.8Very high15 Ų1526.9 Ų26.99%0.09114%0.137CC..THydrogen-bonded Turntrans-63.8-20.5180960000113.3G139 W140 T141 K150 A153 I176 S177G139-V143 PolarHBondContact O-N 3.14Å; W140-V143 HydrophobicContact CE3-CG1 3.97Å; W140-V143 HydrophobicContact CZ3-CG1 4.37Å; W140-V143 WeakPolarHBondContact O-CG1 3.3Å; T141-V143 VanDerWaalsContact C-N 3.28Å; T141-V143 PolarHBondContact O-N 3.34Å; V143-K150 HydrophobicContact CG2-CG 4.24Å; V143-K150 VanDerWaalsContact O-CE 3.22Å; V143-K150 WeakPolarHBondContact O-CE 3.22Å; V143-A153 HydrophobicContact CB-CB 4.49Å; V143-I176 HydrophobicContact CG2-CG2 3.78Å; V143-S177 WeakPolarHBondContact CG2-OG 3.26Å
144K92.8Very high95Very high120 Ų12027.7 Ų27.752%0.52214%0.141SC..THydrogen-bonded Turntrans-79.3-19.4-179.7-61.7167.9-169.8-82.50113M30 L51 W140 T141 L142M30-K144 HydrophobicContact CE-CB 4.07Å; M30-K144 HydrophobicContact CE-CD 4.44Å; L51-K144 HydrophobicContact CD2-CD 3.42Å; L51-K144 VanDerWaalsContact CD2-CD 3.42Å; W140-K144 WeakPolarHBondContact O-CE 3.41Å; T141-K144 WeakPolarHBondContact O-CB 3.38Å; T141-K144 PolarHBondContact O-N 2.94Å; T141-K144 VanDerWaalsContact O-N 3.1Å; L142-K144 PolarHBondContact O-N 3.37Å; L142-K144 VanDerWaalsContact O-N 3.13Å
145F92.2Very high95Very high4 Ų429.2 Ų29.22%0.01816%0.159CC..SBendtrans-94.2-160.4-176-69.7-90.4000112.3L20 M30 T141 L142 K149 K150L20-F145 HydrophobicContact CB-CE1 4.11Å; L20-F145 HydrophobicContact CB-CE2 4.22Å; L20-F145 HydrophobicContact CB-CZ 3.82Å; L20-F145 HydrophobicContact CD1-CE2 4.12Å; L20-F145 HydrophobicContact CD1-CZ 4.12Å; L20-F145 HydrophobicContact CD2-CD2 4.22Å; L20-F145 HydrophobicContact CD2-CE2 3.93Å; L20-F145 HydrophobicContact CD2-CZ 4.39Å; L20-F145 HydrophobicContact CG-CE2 4.31Å; L20-F145 HydrophobicContact CG-CZ 4.32Å; M30-F145 HydrophobicContact CE-CE1 4.3Å; M30-F145 HydrophobicContact CE-CE2 3.96Å; M30-F145 HydrophobicContact CE-CZ 3.74Å; M30-F145 HydrophobicContact SD-CD1 4.37Å; M30-F145 HydrophobicContact SD-CE1 3.75Å; M30-F145 HydrophobicContact SD-CE2 4.46Å; M30-F145 HydrophobicContact SD-CZ 3.8Å; T141-F145 HydrophobicContact CG2-CE2 3.96Å; T141-F145 VanDerWaalsContact O-CD2 3.24Å; T141-F145 WeakPolarHBondContact O-CD2 3.32Å; L142-F145 PolarHBondContact O-N 3.44Å; L142-F145 VanDerWaalsContact O-N 3.17Å; F145-K149 HydrophobicContact CB-CB 3.8Å; F145-K149 HydrophobicContact CB-CG 3.95Å; F145-K150 PolarHBondContact O-NZ 3.05Å
146N89.7Confident95.1Very high33 Ų3331.7 Ų31.718%0.17617%0.168CC..  trans-63.8174.2-176.668.756.1000114.2S148 K149 K150N146-S148 VanDerWaalsContact C-N 3.33Å; N146-S148 PolarHBondContact O-N 3.35Å; N146-S148 WeakPolarHBondContact OD1-CA 3.28Å; N146-S148 WeakPolarHBondContact OD1-CB 3.44Å; N146-S148 PolarHBondContact OD1-N 3.39Å; N146-K149 PolarHBondContact O-N 2.74Å; N146-K149 PolarHBondContact OD1-N 2.98Å; N146-K150 WeakPolarHBondContact O-CG 3.32Å; N146-K150 PolarHBondContact O-N 2.91Å
147K89.4Confident95.2Very high60 Ų6031.7 Ų31.726%0.26117%0.168SC..Hα-helixtrans-60.8-35.6-177.3-78.1-175.1169.7-72.40114K150 S151 K180 C182K147-K150 PolarHBondContact O-N 3.4Å; K147-S151 PolarHBondContact O-N 3.17Å; K147-K180 PolarHBondContact NZ-O 3Å; K147-C182 PolarHBondContact NZ-O 3.27Å
148S89.6Confident95.2Very high56 Ų5635.3 Ų35.339%0.39218%0.184SC..Hα-helixtrans-64.5-45.9176.6176.10000110.6N146 K150 S151 Q152N146-S148 VanDerWaalsContact C-N 3.33Å; N146-S148 PolarHBondContact O-N 3.35Å; N146-S148 WeakPolarHBondContact OD1-CA 3.28Å; N146-S148 WeakPolarHBondContact OD1-CB 3.44Å; N146-S148 PolarHBondContact OD1-N 3.39Å; S148-K150 PolarHBondContact O-N 2.87Å; S148-S151 WeakPolarHBondContact O-CA 3.3Å; S148-S151 VanDerWaalsContact O-CB 3.28Å; S148-S151 WeakPolarHBondContact O-CB 3.42Å; S148-S151 PolarHBondContact O-N 2.7Å; S148-Q152 PolarHBondContact O-N 3.38Å
149K93.9Very high95Very high13 Ų1336.7 Ų36.76%0.05719%0.191CC..Hα-helixtrans-62.9-40.7174.9-62.4-67.1175178.60112D19 L142 F145 N146 S151 Q152 A153D19-K149 WeakPolarHBondContact O-CE 3.41Å; D19-K149 PolarHBondContact O-NZ 2.93Å; D19-K149 IonicContact OD2-NZ 2.76Å; D19-K149 PolarHBondContact OD2-NZ 3.47Å; L142-K149 HydrophobicContact CB-CB 4.4Å; L142-K149 HydrophobicContact CD2-CB 4.01Å; L142-K149 HydrophobicContact CD2-CD 3.53Å; L142-K149 HydrophobicContact CD2-CG 4.24Å; F145-K149 HydrophobicContact CB-CB 3.8Å; F145-K149 HydrophobicContact CB-CG 3.95Å; N146-K149 PolarHBondContact O-N 2.74Å; N146-K149 PolarHBondContact OD1-N 2.98Å; K149-S151 VanDerWaalsContact C-N 3.26Å; K149-S151 PolarHBondContact O-N 2.78Å; K149-Q152 WeakPolarHBondContact O-CB 3.49Å; K149-Q152 PolarHBondContact O-N 2.98Å; K149-Q152 VanDerWaalsContact O-N 3.12Å; K149-A153 PolarHBondContact O-N 3.1Å
150K94.5Very high94.9Very high37 Ų3736.7 Ų36.716%0.16119%0.191CC..Hα-helixtrans-59-35.2171.2-67.7-175.5177.775.50113.2V143 F145 N146 K147 S148 A153 K180 A181V143-K150 HydrophobicContact CG2-CG 4.24Å; V143-K150 VanDerWaalsContact O-CE 3.22Å; V143-K150 WeakPolarHBondContact O-CE 3.22Å; F145-K150 PolarHBondContact O-NZ 3.05Å; N146-K150 WeakPolarHBondContact O-CG 3.32Å; N146-K150 PolarHBondContact O-N 2.91Å; K147-K150 PolarHBondContact O-N 3.4Å; S148-K150 PolarHBondContact O-N 2.87Å; K150-A153 WeakPolarHBondContact O-CB 3.38Å; K150-A153 PolarHBondContact O-N 3.23Å; K150-K180 HydrophobicContact CD-CB 3.6Å; K150-A181 HydrophobicContact CB-CB 4.4Å
151S94.4Very high94.9Very high68 Ų6835.8 Ų35.848%0.47619%0.189SC..Hα-helixtrans-67.5-40.9175-163.80000111.6K147 S148 K149 A153 I154K147-S151 PolarHBondContact O-N 3.17Å; S148-S151 WeakPolarHBondContact O-CA 3.3Å; S148-S151 VanDerWaalsContact O-CB 3.28Å; S148-S151 WeakPolarHBondContact O-CB 3.42Å; S148-S151 PolarHBondContact O-N 2.7Å; K149-S151 VanDerWaalsContact C-N 3.26Å; K149-S151 PolarHBondContact O-N 2.78Å; S151-A153 VanDerWaalsContact C-N 3.33Å; S151-I154 WeakPolarHBondContact O-CB 3.33Å; S151-I154 PolarHBondContact O-N 3.48Å
152Q95.9Very high94.8Very high81 Ų8142.6 Ų42.638%0.37922%0.221SC..Hα-helixtrans-63.8-38.9174.9-65.5174.513.500111.6L142 S148 K149 I154 G155 Y156L142-Q152 HydrophobicContact CD1-CB 4.08Å; S148-Q152 PolarHBondContact O-N 3.38Å; K149-Q152 WeakPolarHBondContact O-CB 3.49Å; K149-Q152 PolarHBondContact O-N 2.98Å; K149-Q152 VanDerWaalsContact O-N 3.12Å; Q152-I154 PolarHBondContact O-N 3.05Å; Q152-I154 VanDerWaalsContact O-N 3.15Å; Q152-G155 PolarHBondContact O-N 3.41Å; Q152-Y156 WeakPolarHBondContact O-CD2 3.3Å; Q152-Y156 PolarHBondContact O-N 2.93Å
153A97.9Very high94.5Very high0 Ų044.1 Ų44.10%023%0.233CC..Hα-helixtrans-55.2-33.117800000113.3G139 L142 V143 K149 K150 S151 G155 Y156 F157G139-A153 WeakPolarHBondContact O-CB 3.24Å; L142-A153 HydrophobicContact CB-CB 3.85Å; V143-A153 HydrophobicContact CB-CB 4.49Å; K149-A153 PolarHBondContact O-N 3.1Å; K150-A153 WeakPolarHBondContact O-CB 3.38Å; K150-A153 PolarHBondContact O-N 3.23Å; S151-A153 VanDerWaalsContact C-N 3.33Å; A153-G155 VanDerWaalsContact C-N 3.31Å; A153-G155 PolarHBondContact O-N 3.02Å; A153-Y156 PolarHBondContact O-N 3.48Å; A153-F157 HydrophobicContact CB-CD2 4.32Å; A153-F157 HydrophobicContact CB-CE2 4.1Å; A153-F157 WeakPolarHBondContact O-CD2 3.36Å; A153-F157 PolarHBondContact O-N 3.36Å
154I97.9Very high94.4Very high30 Ų3046.3 Ų46.315%0.15424%0.243CC..Hα-helixtrans-56.9-45.8177.1-61.9169.5000110.7S151 Q152 F157 K158 L174 M178 A181S151-I154 WeakPolarHBondContact O-CB 3.33Å; S151-I154 PolarHBondContact O-N 3.48Å; Q152-I154 PolarHBondContact O-N 3.05Å; Q152-I154 VanDerWaalsContact O-N 3.15Å; I154-F157 PolarHBondContact O-N 3.48Å; I154-K158 HydrophobicContact CG2-CD 4.23Å; I154-K158 WeakPolarHBondContact O-CG 3.44Å; I154-K158 PolarHBondContact O-N 3.36Å; I154-L174 HydrophobicContact CB-CD1 4.45Å; I154-L174 HydrophobicContact CG2-CD1 3.81Å; I154-M178 HydrophobicContact CD1-CB 4.47Å; I154-M178 HydrophobicContact CD1-CG 3.89Å; I154-M178 HydrophobicContact CG1-CG 3.89Å; I154-M178 HydrophobicContact CG2-CG 4.06Å; I154-A181 HydrophobicContact CD1-CB 3.86Å
155G96.9Very high94.5Very high41 Ų4144 Ų4442%0.42324%0.24SC..Hα-helixtrans-63.3-42.9-179.800000112.1Q152 A153 K158 M159Q152-G155 PolarHBondContact O-N 3.41Å; A153-G155 VanDerWaalsContact C-N 3.31Å; A153-G155 PolarHBondContact O-N 3.02Å; G155-K158 PolarHBondContact O-N 3.36Å; G155-M159 WeakPolarHBondContact O-CB 3.43Å; G155-M159 PolarHBondContact O-N 3.26Å
156Y97.6Very high94.5Very high51 Ų5151.4 Ų51.420%0.228%0.275CS..Hα-helixtrans-69.1-38179.3-68.4-65000113.2L130 S135 K138 L142 Q152 A153 M159 A160L130-Y156 HydrophobicContact CD1-CD1 4.36Å; L130-Y156 HydrophobicContact CD1-CE1 4.03Å; S135-Y156 WeakPolarHBondContact O-CB 3.38Å; K138-Y156 HydrophobicContact CB-CG 4.46Å; K138-Y156 HydrophobicContact CD-CD1 3.99Å; K138-Y156 HydrophobicContact CD-CD2 4.16Å; K138-Y156 HydrophobicContact CD-CE1 3.64Å; K138-Y156 HydrophobicContact CD-CE2 3.79Å; K138-Y156 HydrophobicContact CD-CG 4.25Å; K138-Y156 VanDerWaalsContact CE-OH 3.22Å; K138-Y156 WeakPolarHBondContact CE-OH 3.49Å; K138-Y156 HydrophobicContact CG-CD1 4.45Å; K138-Y156 HydrophobicContact CG-CD2 4.03Å; K138-Y156 HydrophobicContact CG-CE1 4.49Å; K138-Y156 HydrophobicContact CG-CE2 4.03Å; K138-Y156 HydrophobicContact CG-CG 4.24Å; K138-Y156 PolarHBondContact NZ-OH 3.43Å; K138-Y156 VanDerWaalsContact NZ-OH 3.11Å; L142-Y156 HydrophobicContact CD1-CD2 3.53Å; L142-Y156 HydrophobicContact CD1-CE2 3.61Å; Q152-Y156 WeakPolarHBondContact O-CD2 3.3Å; Q152-Y156 PolarHBondContact O-N 2.93Å; A153-Y156 PolarHBondContact O-N 3.48Å; Y156-M159 PolarHBondContact O-N 3.23Å; Y156-A160 WeakPolarHBondContact O-CB 3.45Å; Y156-A160 PolarHBondContact O-N 3.43Å
157F97.9Very high94.7Very high0 Ų053 Ų530%028%0.278CS..Hα-helixtrans-66.9-39.8172.9-71.6-57.2000112.2W140 A153 I154 A160 L161 W170 G173 L174 S177W140-F157 HydrophobicContact CB-CZ 4.41Å; W140-F157 AromaticContact CD1-CE1 3.84Å; W140-F157 HydrophobicContact CD2-CE1 4.14Å; W140-F157 AromaticContact CD2-CZ 3.8Å; W140-F157 HydrophobicContact CD2-CZ 3.8Å; W140-F157 HydrophobicContact CE3-CZ 4.21Å; W140-F157 HydrophobicContact CG-CE1 4.03Å; W140-F157 AromaticContact CG-CZ 3.87Å; W140-F157 HydrophobicContact CG-CZ 3.87Å; W140-F157 VanDerWaalsContact N-CZ 3.3Å; W140-F157 AromaticContact NE1-CE1 3.9Å; A153-F157 HydrophobicContact CB-CD2 4.32Å; A153-F157 HydrophobicContact CB-CE2 4.1Å; A153-F157 WeakPolarHBondContact O-CD2 3.36Å; A153-F157 PolarHBondContact O-N 3.36Å; I154-F157 PolarHBondContact O-N 3.48Å; F157-A160 PolarHBondContact O-N 3.05Å; F157-L161 WeakPolarHBondContact O-CB 3.48Å; F157-L161 VanDerWaalsContact O-CG 3.27Å; F157-L161 WeakPolarHBondContact O-CG 3.31Å; F157-L161 PolarHBondContact O-N 2.98Å; F157-W170 HydrophobicContact CD1-CB 4.09Å; F157-W170 HydrophobicContact CD1-CG 4.45Å; F157-G173 WeakPolarHBondContact CE2-O 3.49Å; F157-G173 VanDerWaalsContact CZ-CA 3.44Å; F157-L174 HydrophobicContact CB-CB 3.92Å; F157-L174 HydrophobicContact CB-CD1 4.22Å; F157-L174 HydrophobicContact CG-CB 4.46Å; F157-S177 VanDerWaalsContact CE2-OG 3.31Å; F157-S177 WeakPolarHBondContact CE2-OG 3.21Å
158K96.6Very high95Very high80 Ų8056 Ų5635%0.34829%0.291SS..Hα-helixtrans-60.3-47.4174.1-74.7-176.6177.2-172.30110.8I154 G155 A160 L161 E162 L174 E194I154-K158 HydrophobicContact CG2-CD 4.23Å; I154-K158 WeakPolarHBondContact O-CG 3.44Å; I154-K158 PolarHBondContact O-N 3.36Å; G155-K158 PolarHBondContact O-N 3.36Å; K158-A160 PolarHBondContact O-N 3.46Å; K158-L161 PolarHBondContact O-N 3.25Å; K158-E162 WeakPolarHBondContact O-CG 3.28Å; K158-E162 PolarHBondContact O-N 3.02Å; K158-L174 HydrophobicContact CG-CD1 3.99Å; K158-L174 HydrophobicContact CG-CD2 4.35Å; K158-E194 IonicContact NZ-OE1 2.66Å; K158-E194 PolarHBondContact NZ-OE1 2.97Å
159M95.3Very high95.2Very high42 Ų4254.9 Ų54.921%0.20728%0.28CS..Hα-helixtrans-59.7-42.2176.6-176.1-172.8-64.800112.9P129 L130 S135 G155 Y156 E162P129-M159 HydrophobicContact CG-CE 3.48Å; P129-M159 VanDerWaalsContact CG-CE 3.48Å; P129-M159 HydrophobicContact CG-SD 3.57Å; P129-M159 VanDerWaalsContact CG-SD 3.57Å; L130-M159 HydrophobicContact CB-SD 4.23Å; L130-M159 HydrophobicContact CD1-SD 4.46Å; L130-M159 HydrophobicContact CG-SD 4.45Å; S135-M159 PolarHBondContact OG-SD 3.31Å; S135-M159 VanDerWaalsContact OG-SD 3.39Å; G155-M159 WeakPolarHBondContact O-CB 3.43Å; G155-M159 PolarHBondContact O-N 3.26Å; Y156-M159 PolarHBondContact O-N 3.23Å; M159-E162 PolarHBondContact O-N 3.38Å
160A95.2Very high95.3Very high0 Ų054.2 Ų54.20%028%0.277CS..Hα-helixtrans-64.5-41.9176.500000111.3Y156 F157 K158 E162 A163 E164 W170Y156-A160 WeakPolarHBondContact O-CB 3.45Å; Y156-A160 PolarHBondContact O-N 3.43Å; F157-A160 PolarHBondContact O-N 3.05Å; K158-A160 PolarHBondContact O-N 3.46Å; A160-E162 VanDerWaalsContact C-N 3.34Å; A160-E162 PolarHBondContact O-N 3.49Å; A160-A163 PolarHBondContact O-N 2.85Å; A160-E164 PolarHBondContact O-N 2.99Å; A160-W170 HydrophobicContact CB-CD2 3.68Å; A160-W170 HydrophobicContact CB-CE3 3.38Å; A160-W170 HydrophobicContact CB-CG 4.29Å; A160-W170 HydrophobicContact CB-CH2 4.28Å; A160-W170 HydrophobicContact CB-CZ3 3.68Å; A160-W170 WeakPolarHBondContact O-CZ3 3.34Å
161L95.8Very high95.4Very high19 Ų1953.7 Ų53.710%0.09928%0.275CS..Hα-helixtrans-71.6-22.4179-72.3168.5000114F157 K158 A163 E164 P165 R167 W170 L174F157-L161 WeakPolarHBondContact O-CB 3.48Å; F157-L161 VanDerWaalsContact O-CG 3.27Å; F157-L161 WeakPolarHBondContact O-CG 3.31Å; F157-L161 PolarHBondContact O-N 2.98Å; K158-L161 PolarHBondContact O-N 3.25Å; L161-A163 VanDerWaalsContact C-N 3.25Å; L161-A163 PolarHBondContact O-N 3.18Å; L161-E164 CarbonylContact O-C 3.48Å; L161-P165 VanDerWaalsContact O-CA 3.24Å; L161-P165 WeakPolarHBondContact O-CA 3.44Å; L161-P165 WeakPolarHBondContact O-CG 3.26Å; L161-R167 HydrophobicContact CD2-CB 4.47Å; L161-W170 HydrophobicContact CD1-CB 4.38Å; L161-W170 HydrophobicContact CD2-CB 3.82Å; L161-W170 HydrophobicContact CD2-CE3 4.37Å; L161-W170 HydrophobicContact CG-CB 3.87Å; L161-L174 HydrophobicContact CD1-CB 4.45Å; L161-L174 HydrophobicContact CD1-CD2 3.87Å
162E94.3Very high95.6Very high145 Ų14553 Ų5368%0.67826%0.263SS*.Hα-helixtrans-62.7-36.5170.4-76.8167.4-170.400111.4K158 M159 A160K158-E162 WeakPolarHBondContact O-CG 3.28Å; K158-E162 PolarHBondContact O-N 3.02Å; M159-E162 PolarHBondContact O-N 3.38Å; A160-E162 VanDerWaalsContact C-N 3.34Å; A160-E162 PolarHBondContact O-N 3.49Å
163A91.9Very high95.6Very high32 Ų3249.1 Ų49.126%0.26425%0.245SC..Hα-helixtrans-83.6-41.6178.100000113.1P125 P132 A160 L161P125-A163 HydrophobicContact CB-CB 4.44Å; P125-A163 HydrophobicContact CG-CB 3.95Å; P132-A163 HydrophobicContact CB-CB 4.11Å; P132-A163 HydrophobicContact CG-CB 3.3Å; A160-A163 PolarHBondContact O-N 2.85Å; L161-A163 VanDerWaalsContact C-N 3.25Å; L161-A163 PolarHBondContact O-N 3.18Å
164E92.5Very high95.6Very high61 Ų6149.5 Ų49.529%0.28525%0.247SC..  trans-130.986.1177.7-52.5172.8-143.400111.4A160 L161 E166 R167 W170A160-E164 PolarHBondContact O-N 2.99Å; L161-E164 CarbonylContact O-C 3.48Å; E164-E166 PolarHBondContact O-N 2.78Å; E164-R167 HydrophobicContact CB-CG 3.49Å; E164-R167 VanDerWaalsContact CB-CG 3.49Å; E164-R167 HydrophobicContact CG-CG 4.42Å; E164-R167 PolarHBondContact O-N 3.26Å; E164-R167 WeakPolarHBondContact OE2-CD 3.35Å; E164-R167 WeakPolarHBondContact OE2-CG 3.35Å; E164-R167 IonicContact OE2-CZ 2.63Å; E164-R167 IonicContact OE2-NE 3.02Å; E164-R167 IonicContact OE2-NH1 4Å; E164-W170 HydrophobicContact CB-CH2 4.36Å; E164-W170 HydrophobicContact CB-CZ3 3.72Å; E164-W170 HydrophobicContact CG-CH2 4.36Å; E164-W170 HydrophobicContact CG-CZ3 4.13Å
165P94.1Very high95.6Very high71 Ų7148 Ų4846%0.46124%0.24SC..THydrogen-bonded Turntrans-63.2-24.3-173.1-25.634.4000115.3L161 R167 H171L161-P165 VanDerWaalsContact O-CA 3.24Å; L161-P165 WeakPolarHBondContact O-CA 3.44Å; L161-P165 WeakPolarHBondContact O-CG 3.26Å; P165-R167 VanDerWaalsContact C-N 3.34Å; P165-H171 PolarHBondContact O-NE2 3.44Å
166E93.4Very high95.5Very high160 Ų16046.8 Ų46.875%0.74822%0.223SC*.THydrogen-bonded Turntrans-891.8-174.2-59-55.9133.700113.3E164 K168E164-E166 PolarHBondContact O-N 2.78Å; E166-K168 PolarHBondContact O-N 3.14Å
167R93.3Very high95.5Very high66 Ų6644.3 Ų44.325%0.24921%0.213CC..  trans-73.495.7-176.1-68.6-70.6-75.6-139-7111.7E133 L161 E164 P165 E169 W170 H171E133-R167 IonicContact OE1-CZ 3.15Å; E133-R167 IonicContact OE1-NH1 3.67Å; E133-R167 IonicContact OE1-NH2 2.7Å; E133-R167 PolarHBondContact OE1-NH2 2.64Å; E133-R167 IonicContact OE2-NH2 3.21Å; L161-R167 HydrophobicContact CD2-CB 4.47Å; E164-R167 HydrophobicContact CB-CG 3.49Å; E164-R167 VanDerWaalsContact CB-CG 3.49Å; E164-R167 HydrophobicContact CG-CG 4.42Å; E164-R167 PolarHBondContact O-N 3.26Å; E164-R167 WeakPolarHBondContact OE2-CD 3.35Å; E164-R167 WeakPolarHBondContact OE2-CG 3.35Å; E164-R167 IonicContact OE2-CZ 2.63Å; E164-R167 IonicContact OE2-NE 3.02Å; E164-R167 IonicContact OE2-NH1 4Å; P165-R167 VanDerWaalsContact C-N 3.34Å; R167-E169 PolarHBondContact O-N 3.41Å; R167-E169 VanDerWaalsContact O-N 3.13Å; R167-W170 HydrophobicContact CB-CB 4.41Å; R167-W170 HydrophobicContact CB-CD2 3.72Å; R167-W170 HydrophobicContact CB-CE3 3.48Å; R167-W170 VanDerWaalsContact CB-CE3 3.48Å; R167-W170 HydrophobicContact CB-CG 4.17Å; R167-W170 HydrophobicContact CB-CZ3 3.98Å; R167-W170 HydrophobicContact CG-CD2 4.22Å; R167-W170 HydrophobicContact CG-CE3 3.73Å; R167-W170 HydrophobicContact CG-CH2 4.01Å; R167-W170 HydrophobicContact CG-CZ2 4.48Å; R167-W170 HydrophobicContact CG-CZ3 3.65Å; R167-W170 PolarHBondContact O-N 3.37Å; R167-H171 PolarHBondContact O-CD2 3.34Å; R167-H171 PolarHBondContact O-N 3.47Å
168K95.3Very high95.4Very high122 Ų12244.9 Ų44.953%0.5322%0.216SC..Hα-helixtrans-48.2-39.6176.863.1179.1-179.9175.50114.4E166 W170 H171 K172 I205E166-K168 PolarHBondContact O-N 3.14Å; K168-W170 VanDerWaalsContact C-N 3.34Å; K168-W170 PolarHBondContact O-N 3.45Å; K168-H171 PolarHBondContact O-N 3.02Å; K168-K172 PolarHBondContact O-N 2.93Å; K168-I205 HydrophobicContact CB-CG2 3.63Å
169E93.8Very high95.3Very high33 Ų3341.9 Ų41.915%0.15421%0.205CC..Hα-helixtrans-63-41.5-179-171.4-177.4148.100111.2S43 H47 W140 R167 K172 G173S43-E169 PolarHBondContact OG-OE2 2.82Å; H47-E169 IonicContact CE1-OE1 2.63Å; H47-E169 IonicContact ND1-OE1 3.84Å; W140-E169 HydrophobicContact CZ2-CG 3.65Å; W140-E169 WeakPolarHBondContact CZ2-O 3.15Å; W140-E169 VanDerWaalsContact NE1-CG 3.33Å; W140-E169 PolarHBondContact NE1-OE1 3.22Å; R167-E169 PolarHBondContact O-N 3.41Å; R167-E169 VanDerWaalsContact O-N 3.13Å; E169-K172 WeakPolarHBondContact O-CB 3.33Å; E169-K172 PolarHBondContact O-N 2.73Å; E169-G173 PolarHBondContact O-N 2.74Å
170W96.3Very high95.1Very high0 Ų043.7 Ų43.70%021%0.212CC..Hα-helixtrans-78-32.1-177.7-56.4-21.6000112.2P132 F157 A160 L161 E164 R167 K168 K172 G173 L174P132-W170 HydrophobicContact CB-CH2 3.42Å; P132-W170 VanDerWaalsContact CB-CH2 3.42Å; P132-W170 HydrophobicContact CB-CZ2 4.37Å; P132-W170 HydrophobicContact CB-CZ3 3.77Å; F157-W170 HydrophobicContact CD1-CB 4.09Å; F157-W170 HydrophobicContact CD1-CG 4.45Å; A160-W170 HydrophobicContact CB-CD2 3.68Å; A160-W170 HydrophobicContact CB-CE3 3.38Å; A160-W170 HydrophobicContact CB-CG 4.29Å; A160-W170 HydrophobicContact CB-CH2 4.28Å; A160-W170 HydrophobicContact CB-CZ3 3.68Å; A160-W170 WeakPolarHBondContact O-CZ3 3.34Å; L161-W170 HydrophobicContact CD1-CB 4.38Å; L161-W170 HydrophobicContact CD2-CB 3.82Å; L161-W170 HydrophobicContact CD2-CE3 4.37Å; L161-W170 HydrophobicContact CG-CB 3.87Å; E164-W170 HydrophobicContact CB-CH2 4.36Å; E164-W170 HydrophobicContact CB-CZ3 3.72Å; E164-W170 HydrophobicContact CG-CH2 4.36Å; E164-W170 HydrophobicContact CG-CZ3 4.13Å; R167-W170 HydrophobicContact CB-CB 4.41Å; R167-W170 HydrophobicContact CB-CD2 3.72Å; R167-W170 HydrophobicContact CB-CE3 3.48Å; R167-W170 VanDerWaalsContact CB-CE3 3.48Å; R167-W170 HydrophobicContact CB-CG 4.17Å; R167-W170 HydrophobicContact CB-CZ3 3.98Å; R167-W170 HydrophobicContact CG-CD2 4.22Å; R167-W170 HydrophobicContact CG-CE3 3.73Å; R167-W170 HydrophobicContact CG-CH2 4.01Å; R167-W170 HydrophobicContact CG-CZ2 4.48Å; R167-W170 HydrophobicContact CG-CZ3 3.65Å; R167-W170 PolarHBondContact O-N 3.37Å; K168-W170 VanDerWaalsContact C-N 3.34Å; K168-W170 PolarHBondContact O-N 3.45Å; W170-K172 VanDerWaalsContact C-N 3.31Å; W170-K172 PolarHBondContact O-N 3.2Å; W170-G173 PolarHBondContact O-N 3.43Å; W170-L174 WeakPolarHBondContact O-CB 3.31Å; W170-L174 PolarHBondContact O-N 3.34Å
171H97.8Very high94.8Very high25 Ų2544.3 Ų44.312%0.11622%0.217CC..Hα-helixtrans-58.6-43.9167.2-80.5-69.3000111.8P165 R167 K168 L174 A175 A202 I205P165-H171 PolarHBondContact O-NE2 3.44Å; R167-H171 PolarHBondContact O-CD2 3.34Å; R167-H171 PolarHBondContact O-N 3.47Å; K168-H171 PolarHBondContact O-N 3.02Å; H171-L174 PolarHBondContact O-N 2.78Å; H171-A175 WeakPolarHBondContact O-CB 3.32Å; H171-A175 PolarHBondContact O-N 3.48Å; H171-A202 HydrophobicContact CB-CB 4Å; H171-I205 HydrophobicContact CB-CD1 4.38Å; H171-I205 WeakPolarHBondContact CD2-CD1 3.34Å; H171-I205 WeakPolarHBondContact NE2-CD1 3.48Å
172K97Very high94.2Very high54 Ų5445.5 Ų45.524%0.23523%0.227CC..Hα-helixtrans-61.1-47.1174-175.7177.1179.81740111.6W140 K168 E169 W170 L174 A175 I176 D209 L212W140-K172 HydrophobicContact CH2-CB 4.41Å; W140-K172 HydrophobicContact CH2-CD 4.32Å; W140-K172 HydrophobicContact CH2-CG 4.11Å; K168-K172 PolarHBondContact O-N 2.93Å; E169-K172 WeakPolarHBondContact O-CB 3.33Å; E169-K172 PolarHBondContact O-N 2.73Å; W170-K172 VanDerWaalsContact C-N 3.31Å; W170-K172 PolarHBondContact O-N 3.2Å; K172-L174 VanDerWaalsContact C-N 3.34Å; K172-L174 PolarHBondContact O-N 3.13Å; K172-A175 PolarHBondContact O-N 3.46Å; K172-I176 HydrophobicContact CG-CD1 3.92Å; K172-I176 WeakPolarHBondContact O-CG1 3.44Å; K172-I176 PolarHBondContact O-N 2.66Å; K172-D209 VanDerWaalsContact CE-OD2 3.3Å; K172-D209 WeakPolarHBondContact CE-OD2 3.42Å; K172-D209 IonicContact NZ-OD1 3.72Å; K172-D209 IonicContact NZ-OD2 3.01Å; K172-D209 PolarHBondContact NZ-OD2 3.17Å; K172-L212 HydrophobicContact CB-CD1 4.04Å; K172-L212 HydrophobicContact CB-CD2 4.39Å; K172-L212 HydrophobicContact CD-CD1 4.31Å; K172-L212 HydrophobicContact CD-CG 4.47Å; K172-L212 HydrophobicContact CG-CD1 4.03Å; K172-L212 HydrophobicContact CG-CD2 4.02Å; K172-L212 HydrophobicContact CG-CG 4.07Å
173G96.6Very high93.6Very high0 Ų039.7 Ų39.70%020%0.2CC..Hα-helixtrans-57.5-44.8176.400000112.8F157 E169 W170 I176 S177F157-G173 WeakPolarHBondContact CE2-O 3.49Å; F157-G173 VanDerWaalsContact CZ-CA 3.44Å; E169-G173 PolarHBondContact O-N 2.74Å; W170-G173 PolarHBondContact O-N 3.43Å; G173-I176 PolarHBondContact O-N 2.88Å; G173-S177 WeakPolarHBondContact O-CB 3.25Å; G173-S177 PolarHBondContact O-N 3.38Å; G173-S177 PolarHBondContact O-OG 3.48Å
174L97.9Very high93.3Very high7 Ų741 Ų414%0.03720%0.198CC..Hα-helixtrans-61.9-51.8177.1-178.660000111.4I154 F157 K158 L161 W170 H171 K172 I176 S177 M178I154-L174 HydrophobicContact CB-CD1 4.45Å; I154-L174 HydrophobicContact CG2-CD1 3.81Å; F157-L174 HydrophobicContact CB-CB 3.92Å; F157-L174 HydrophobicContact CB-CD1 4.22Å; F157-L174 HydrophobicContact CG-CB 4.46Å; K158-L174 HydrophobicContact CG-CD1 3.99Å; K158-L174 HydrophobicContact CG-CD2 4.35Å; L161-L174 HydrophobicContact CD1-CB 4.45Å; L161-L174 HydrophobicContact CD1-CD2 3.87Å; W170-L174 WeakPolarHBondContact O-CB 3.31Å; W170-L174 PolarHBondContact O-N 3.34Å; H171-L174 PolarHBondContact O-N 2.78Å; K172-L174 VanDerWaalsContact C-N 3.34Å; K172-L174 PolarHBondContact O-N 3.13Å; L174-I176 VanDerWaalsContact C-N 3.3Å; L174-I176 PolarHBondContact O-N 3.06Å; L174-S177 PolarHBondContact O-N 3.36Å; L174-S177 VanDerWaalsContact O-N 3.14Å; L174-M178 HydrophobicContact CD1-CG 3.92Å; L174-M178 HydrophobicContact CD1-SD 3.72Å; L174-M178 HydrophobicContact CD2-SD 4.49Å; L174-M178 HydrophobicContact CG-CG 4.39Å; L174-M178 HydrophobicContact CG-SD 3.85Å; L174-M178 WeakPolarHBondContact O-CB 3.34Å; L174-M178 WeakPolarHBondContact O-CG 3.35Å; L174-M178 PolarHBondContact O-N 3.01Å
175A97.3Very high92.9Very high0 Ų044.4 Ų44.40%021%0.21CC..Hα-helixtrans-57.1-42.3178.900000112.3H171 K172 S179 V199 A202 L212H171-A175 WeakPolarHBondContact O-CB 3.32Å; H171-A175 PolarHBondContact O-N 3.48Å; K172-A175 PolarHBondContact O-N 3.46Å; A175-S179 VanDerWaalsContact O-CB 3.26Å; A175-S179 WeakPolarHBondContact O-CB 3.41Å; A175-S179 PolarHBondContact O-N 3.21Å; A175-S179 VanDerWaalsContact O-N 3.1Å; A175-S179 PolarHBondContact O-OG 3.19Å; A175-V199 HydrophobicContact CB-CG2 3.96Å; A175-A202 HydrophobicContact CB-CB 3.94Å; A175-L212 HydrophobicContact CB-CD2 4.25Å
176I96.1Very high92.6Very high14 Ų1445.3 Ų45.37%0.07221%0.206CC..Hα-helixtrans-64.1-48175.8-68.7170.1000111.2W140 V143 K172 G173 L174 S179 K180 F211W140-I176 HydrophobicContact CH2-CD1 4.07Å; W140-I176 HydrophobicContact CZ3-CD1 4.01Å; V143-I176 HydrophobicContact CG2-CG2 3.78Å; K172-I176 HydrophobicContact CG-CD1 3.92Å; K172-I176 WeakPolarHBondContact O-CG1 3.44Å; K172-I176 PolarHBondContact O-N 2.66Å; G173-I176 PolarHBondContact O-N 2.88Å; L174-I176 VanDerWaalsContact C-N 3.3Å; L174-I176 PolarHBondContact O-N 3.06Å; I176-S179 PolarHBondContact O-N 3.2Å; I176-K180 HydrophobicContact CG2-CD 4.07Å; I176-K180 WeakPolarHBondContact O-CB 3.43Å; I176-K180 WeakPolarHBondContact O-CG 3.46Å; I176-K180 PolarHBondContact O-N 3.44Å; I176-F211 HydrophobicContact CD1-CD1 4.44Å; I176-F211 HydrophobicContact CD1-CE1 3.55Å; I176-F211 HydrophobicContact CD1-CZ 3.67Å; I176-F211 HydrophobicContact CG1-CE1 3.37Å; I176-F211 HydrophobicContact CG1-CZ 3.59Å
177S96.7Very high92.4Very high0 Ų038 Ų380%017%0.173CC..Hα-helixtrans-63-50.5-175.7-59.30000110.6V143 F157 G173 L174 S179 K180 A181V143-S177 WeakPolarHBondContact CG2-OG 3.26Å; F157-S177 VanDerWaalsContact CE2-OG 3.31Å; F157-S177 WeakPolarHBondContact CE2-OG 3.21Å; G173-S177 WeakPolarHBondContact O-CB 3.25Å; G173-S177 PolarHBondContact O-N 3.38Å; G173-S177 PolarHBondContact O-OG 3.48Å; L174-S177 PolarHBondContact O-N 3.36Å; L174-S177 VanDerWaalsContact O-N 3.14Å; S177-S179 VanDerWaalsContact C-N 3.34Å; S177-S179 PolarHBondContact O-N 2.71Å; S177-K180 PolarHBondContact O-N 2.89Å; S177-K180 VanDerWaalsContact O-N 3.11Å; S177-A181 VanDerWaalsContact O-CB 3.26Å; S177-A181 WeakPolarHBondContact O-CB 3.39Å; S177-A181 PolarHBondContact O-N 3.22Å
178M96.4Very high92.5Very high11 Ų1137.7 Ų37.75%0.05418%0.178CC..Hα-helixtrans-60.1-42.6178-68.3-177.173.600112I154 L174 K180 E194 I195 K198I154-M178 HydrophobicContact CD1-CB 4.47Å; I154-M178 HydrophobicContact CD1-CG 3.89Å; I154-M178 HydrophobicContact CG1-CG 3.89Å; I154-M178 HydrophobicContact CG2-CG 4.06Å; L174-M178 HydrophobicContact CD1-CG 3.92Å; L174-M178 HydrophobicContact CD1-SD 3.72Å; L174-M178 HydrophobicContact CD2-SD 4.49Å; L174-M178 HydrophobicContact CG-CG 4.39Å; L174-M178 HydrophobicContact CG-SD 3.85Å; L174-M178 WeakPolarHBondContact O-CB 3.34Å; L174-M178 WeakPolarHBondContact O-CG 3.35Å; L174-M178 PolarHBondContact O-N 3.01Å; M178-K180 PolarHBondContact O-N 3.39Å; M178-E194 HydrophobicContact CE-CB 4.46Å; M178-E194 HydrophobicContact CE-CG 3.8Å; M178-E194 WeakPolarHBondContact CE-OE1 3.42Å; M178-I195 HydrophobicContact CB-CG1 4.1Å; M178-I195 HydrophobicContact CE-CG1 4.3Å; M178-K198 HydrophobicContact CE-CG 4.02Å; M178-K198 HydrophobicContact SD-CB 3.91Å; M178-K198 HydrophobicContact SD-CG 3.71Å
179S94.2Very high92.5Very high18 Ų1836.5 Ų36.513%0.12618%0.183CC..Hα-helixtrans-66.6-19.6178.3-65.70000114.4A175 I176 S177A175-S179 VanDerWaalsContact O-CB 3.26Å; A175-S179 WeakPolarHBondContact O-CB 3.41Å; A175-S179 PolarHBondContact O-N 3.21Å; A175-S179 VanDerWaalsContact O-N 3.1Å; A175-S179 PolarHBondContact O-OG 3.19Å; I176-S179 PolarHBondContact O-N 3.2Å; S177-S179 VanDerWaalsContact C-N 3.34Å; S177-S179 PolarHBondContact O-N 2.71Å
180K91.4Very high92.5Very high79 Ų7941.3 Ų41.334%0.34321%0.205SC..Hα-helixtrans-119.4-12.4-171.4-67-177.3-178.3176.50114.6K147 K150 I176 S177 M178 Y250K147-K180 PolarHBondContact NZ-O 3Å; K150-K180 HydrophobicContact CD-CB 3.6Å; I176-K180 HydrophobicContact CG2-CD 4.07Å; I176-K180 WeakPolarHBondContact O-CB 3.43Å; I176-K180 WeakPolarHBondContact O-CG 3.46Å; I176-K180 PolarHBondContact O-N 3.44Å; S177-K180 PolarHBondContact O-N 2.89Å; S177-K180 VanDerWaalsContact O-N 3.11Å; M178-K180 PolarHBondContact O-N 3.39Å; K180-Y250 WeakPolarHBondContact CE-OH 3.39Å; K180-Y250 PolarHBondContact NZ-OH 3.44Å
181A88.9Confident92.5Very high14 Ų1445.4 Ų45.412%0.11623%0.225CC..Hα-helixtrans-66.2-52.3-179.400000112.1K150 I154 S177K150-A181 HydrophobicContact CB-CB 4.4Å; I154-A181 HydrophobicContact CD1-CB 3.86Å; S177-A181 VanDerWaalsContact O-CB 3.26Å; S177-A181 WeakPolarHBondContact O-CB 3.39Å; S177-A181 PolarHBondContact O-N 3.22Å
182C82.2Confident92.4Very high44 Ų4446.6 Ų46.630%0.29723%0.23SC..SBendtrans-88.5167.617661.70000112.7K147 C187K147-C182 PolarHBondContact NZ-O 3.27Å; C182-C187 WeakPolarHBondContact CB-SG 3.44Å; C182-C187 WeakPolarHBondContact SG-CB 3.38Å; C182-C187 CovalentContact SG-SG 2.08Å; C182-C187 PolarHBondContact SG-SG 3.35Å
183L82.6Confident92.4Very high23 Ų2346.4 Ų46.412%0.1224%0.238CC..  trans-85.1123.8164.8-70.8165.5000107.3Y185 K186 C187 Y398L183-Y185 HydrophobicContact CB-CD1 4.03Å; L183-Y185 HydrophobicContact CB-CE1 3.71Å; L183-Y185 HydrophobicContact CD1-CE1 3.91Å; L183-Y185 HydrophobicContact CD2-CE1 4.34Å; L183-Y185 HydrophobicContact CG-CE1 4.21Å; L183-Y185 PolarHBondContact O-N 2.76Å; L183-K186 HydrophobicContact CB-CB 4.4Å; L183-K186 HydrophobicContact CB-CD 4.46Å; L183-K186 HydrophobicContact CB-CG 4.26Å; L183-K186 HydrophobicContact CD1-CD 4.17Å; L183-K186 WeakPolarHBondContact O-CA 3.45Å; L183-K186 WeakPolarHBondContact O-CB 3.36Å; L183-K186 PolarHBondContact O-N 2.94Å; L183-C187 PolarHBondContact O-N 2.73Å; L183-C187 PolarHBondContact O-SG 2.94Å; L183-Y398 HydrophobicContact CD1-CD2 3.77Å; L183-Y398 HydrophobicContact CD1-CG 4.35Å; L183-Y398 HydrophobicContact CD2-CD2 4.25Å
184W85.9Confident92.4Very high58 Ų5849.9 Ų49.922%0.2225%0.254CS..G310 helixtrans-52.9-37.1-169.5-172.2-117.8000114.6K186 C187 K192 I195 K219 E222 V223W184-K186 VanDerWaalsContact C-N 3.26Å; W184-K186 PolarHBondContact O-N 3.42Å; W184-C187 PolarHBondContact O-N 3.17Å; W184-K192 HydrophobicContact CE3-CG 4.33Å; W184-K192 HydrophobicContact CH2-CB 3.8Å; W184-K192 HydrophobicContact CH2-CD 4.16Å; W184-K192 HydrophobicContact CH2-CG 3.54Å; W184-K192 HydrophobicContact CZ2-CB 4.24Å; W184-K192 HydrophobicContact CZ2-CD 3.85Å; W184-K192 HydrophobicContact CZ2-CG 3.77Å; W184-K192 HydrophobicContact CZ3-CB 4.38Å; W184-K192 HydrophobicContact CZ3-CG 3.84Å; W184-K192 WeakPolarHBondContact O-CE 3.33Å; W184-I195 HydrophobicContact CE3-CD1 4.5Å; W184-I195 HydrophobicContact CZ3-CB 4.45Å; W184-I195 HydrophobicContact CZ3-CD1 3.81Å; W184-I195 HydrophobicContact CZ3-CG2 4.2Å; W184-K219 HydrophobicContact CH2-CD 4.06Å; W184-K219 HydrophobicContact CZ2-CD 4.42Å; W184-K219 HydrophobicContact CZ3-CD 4.44Å; W184-E222 HydrophobicContact CZ2-CB 3.76Å; W184-V223 HydrophobicContact CH2-CG2 3.59Å; W184-V223 HydrophobicContact CZ2-CG2 3.54Å
185Y83.9Confident92.4Very high133 Ų13349.9 Ų49.952%0.52225%0.254SS..G310 helixtrans-71.5-16.9178.473.3-94.4000114.2L183 Y398L183-Y185 HydrophobicContact CB-CD1 4.03Å; L183-Y185 HydrophobicContact CB-CE1 3.71Å; L183-Y185 HydrophobicContact CD1-CE1 3.91Å; L183-Y185 HydrophobicContact CD2-CE1 4.34Å; L183-Y185 HydrophobicContact CG-CE1 4.21Å; L183-Y185 PolarHBondContact O-N 2.76Å; Y185-Y398 HydrophobicContact CE1-CD2 4.13Å; Y185-Y398 HydrophobicContact CE1-CE2 4.01Å; Y185-Y398 WeakPolarHBondContact OH-CD2 3.45Å; Y185-Y398 WeakPolarHBondContact OH-CE2 3.25Å
186K86.9Confident92.5Very high90 Ų9050.6 Ų50.639%0.39126%0.258SS..G310 helixtrans-93.5-15.2175.6-68-167167.4-172.60113.2L183 W184 Y396 D401L183-K186 HydrophobicContact CB-CB 4.4Å; L183-K186 HydrophobicContact CB-CD 4.46Å; L183-K186 HydrophobicContact CB-CG 4.26Å; L183-K186 HydrophobicContact CD1-CD 4.17Å; L183-K186 WeakPolarHBondContact O-CA 3.45Å; L183-K186 WeakPolarHBondContact O-CB 3.36Å; L183-K186 PolarHBondContact O-N 2.94Å; W184-K186 VanDerWaalsContact C-N 3.26Å; W184-K186 PolarHBondContact O-N 3.42Å; K186-Y396 PolarHBondContact NZ-OH 3.39Å; K186-D401 IonicContact NZ-OD1 3.8Å; K186-D401 PolarHBondContact NZ-OD1 2.86Å; K186-D401 IonicContact NZ-OD2 3.87Å; K186-D401 PolarHBondContact NZ-OD2 3.13Å
187C90.3Very high92.5Very high8 Ų854.7 Ų54.75%0.05428%0.277CS..SBendtrans-76.1137-176.9-33.40000109.2C182 L183 W184 Q191 K192C182-C187 WeakPolarHBondContact CB-SG 3.44Å; C182-C187 WeakPolarHBondContact SG-CB 3.38Å; C182-C187 CovalentContact SG-SG 2.08Å; C182-C187 PolarHBondContact SG-SG 3.35Å; L183-C187 PolarHBondContact O-N 2.73Å; L183-C187 PolarHBondContact O-SG 2.94Å; W184-C187 PolarHBondContact O-N 3.17Å; C187-Q191 VanDerWaalsContact CA-OE1 3.25Å; C187-Q191 HydrophobicContact CB-CB 4.17Å; C187-K192 HydrophobicContact CB-CG 4.21Å; C187-K192 WeakPolarHBondContact O-CE 3.38Å
188T94.3Very high92.6Very high58 Ų5857.5 Ų57.536%0.35629%0.289SS..  trans-69.4162.6179.277.70000111.1E190 Q191 K192T188-E190 WeakPolarHBondContact CB-OE2 3.39Å; T188-E190 PolarHBondContact O-N 2.87Å; T188-E190 PolarHBondContact OG1-N 3.06Å; T188-E190 PolarHBondContact OG1-OE2 3.01Å; T188-Q191 PolarHBondContact O-N 3.32Å; T188-Q191 WeakPolarHBondContact OG1-CG 3.29Å; T188-Q191 PolarHBondContact OG1-N 3.23Å; T188-K192 WeakPolarHBondContact O-CG 3.44Å; T188-K192 PolarHBondContact O-N 3.04Å
189P94.9Very high92.7Very high97 Ų9757 Ų5763%0.6329%0.286SS*.Hα-helixtrans-52.8-39.7173.7-27.337000113.4K192 A193P189-K192 WeakPolarHBondContact O-CB 3.45Å; P189-K192 PolarHBondContact O-N 3.29Å; P189-A193 PolarHBondContact O-N 3.13Å
190E95.8Very high92.9Very high134 Ų13460.1 Ų60.163%0.62630%0.298SS*.Hα-helixtrans-66.6-44.7179.6-55.870-148.300111T188 K192 A193 E194T188-E190 WeakPolarHBondContact CB-OE2 3.39Å; T188-E190 PolarHBondContact O-N 2.87Å; T188-E190 PolarHBondContact OG1-N 3.06Å; T188-E190 PolarHBondContact OG1-OE2 3.01Å; E190-K192 VanDerWaalsContact C-N 3.31Å; E190-K192 PolarHBondContact O-N 3.22Å; E190-A193 PolarHBondContact O-N 2.87Å; E190-E194 PolarHBondContact O-N 3.5Å
191Q95.1Very high93.2Very high86 Ų8658.4 Ų58.440%0.40229%0.294SS..Hα-helixtrans-62.5-39.8175.3-69.6175.7-31.600111.6C187 T188 A193 E194 I195C187-Q191 VanDerWaalsContact CA-OE1 3.25Å; C187-Q191 HydrophobicContact CB-CB 4.17Å; T188-Q191 PolarHBondContact O-N 3.32Å; T188-Q191 WeakPolarHBondContact OG1-CG 3.29Å; T188-Q191 PolarHBondContact OG1-N 3.23Å; Q191-A193 VanDerWaalsContact C-N 3.34Å; Q191-E194 PolarHBondContact O-N 2.86Å; Q191-I195 WeakPolarHBondContact O-CB 3.46Å; Q191-I195 WeakPolarHBondContact O-CD1 3.07Å; Q191-I195 WeakPolarHBondContact O-CG1 3.31Å; Q191-I195 PolarHBondContact O-N 2.87Å
192K96.6Very high93.6Very high51 Ų5157.8 Ų57.822%0.22229%0.289CS..Hα-helixtrans-64.2-39.9176.4-72.2-179.7177.5175.60111.7W184 C187 T188 P189 E190 I195 L196 V223W184-K192 HydrophobicContact CE3-CG 4.33Å; W184-K192 HydrophobicContact CH2-CB 3.8Å; W184-K192 HydrophobicContact CH2-CD 4.16Å; W184-K192 HydrophobicContact CH2-CG 3.54Å; W184-K192 HydrophobicContact CZ2-CB 4.24Å; W184-K192 HydrophobicContact CZ2-CD 3.85Å; W184-K192 HydrophobicContact CZ2-CG 3.77Å; W184-K192 HydrophobicContact CZ3-CB 4.38Å; W184-K192 HydrophobicContact CZ3-CG 3.84Å; W184-K192 WeakPolarHBondContact O-CE 3.33Å; C187-K192 HydrophobicContact CB-CG 4.21Å; C187-K192 WeakPolarHBondContact O-CE 3.38Å; T188-K192 WeakPolarHBondContact O-CG 3.44Å; T188-K192 PolarHBondContact O-N 3.04Å; P189-K192 WeakPolarHBondContact O-CB 3.45Å; P189-K192 PolarHBondContact O-N 3.29Å; E190-K192 VanDerWaalsContact C-N 3.31Å; E190-K192 PolarHBondContact O-N 3.22Å; K192-I195 PolarHBondContact O-N 2.98Å; K192-L196 WeakPolarHBondContact O-CB 3.47Å; K192-L196 PolarHBondContact O-N 3.19Å; K192-V223 HydrophobicContact CB-CG1 4.42Å; K192-V223 HydrophobicContact CB-CG2 4.02Å
193A96.9Very high94.4Very high50 Ų5055.9 Ų55.941%0.41328%0.276SS..Hα-helixtrans-65.2-44.8175.100000111.9P189 E190 Q191 I195 L196 E197P189-A193 PolarHBondContact O-N 3.13Å; E190-A193 PolarHBondContact O-N 2.87Å; Q191-A193 VanDerWaalsContact C-N 3.34Å; A193-I195 VanDerWaalsContact C-N 3.34Å; A193-I195 PolarHBondContact O-N 3.39Å; A193-L196 PolarHBondContact O-N 3.07Å; A193-E197 PolarHBondContact O-N 2.87Å
194E96.9Very high95.1Very high72 Ų7260.4 Ų60.434%0.33630%0.297SS..Hα-helixtrans-59.8-44.1175.3-166.5-163.616200111.1K158 M178 E190 Q191 L196 E197 K198K158-E194 IonicContact NZ-OE1 2.66Å; K158-E194 PolarHBondContact NZ-OE1 2.97Å; M178-E194 HydrophobicContact CE-CB 4.46Å; M178-E194 HydrophobicContact CE-CG 3.8Å; M178-E194 WeakPolarHBondContact CE-OE1 3.42Å; E190-E194 PolarHBondContact O-N 3.5Å; Q191-E194 PolarHBondContact O-N 2.86Å; E194-L196 PolarHBondContact O-N 3.41Å; E194-E197 PolarHBondContact O-N 3.22Å; E194-K198 WeakPolarHBondContact O-CG 3.22Å; E194-K198 PolarHBondContact O-N 2.93Å
195I97.4Very high95.6Very high8 Ų860.5 Ų60.54%0.04130%0.301CS..Hα-helixtrans-60.3-47.1176.4-69.7163.9000110.7M178 W184 Q191 K192 A193 E197 K198 V199M178-I195 HydrophobicContact CB-CG1 4.1Å; M178-I195 HydrophobicContact CE-CG1 4.3Å; W184-I195 HydrophobicContact CE3-CD1 4.5Å; W184-I195 HydrophobicContact CZ3-CB 4.45Å; W184-I195 HydrophobicContact CZ3-CD1 3.81Å; W184-I195 HydrophobicContact CZ3-CG2 4.2Å; Q191-I195 WeakPolarHBondContact O-CB 3.46Å; Q191-I195 WeakPolarHBondContact O-CD1 3.07Å; Q191-I195 WeakPolarHBondContact O-CG1 3.31Å; Q191-I195 PolarHBondContact O-N 2.87Å; K192-I195 PolarHBondContact O-N 2.98Å; A193-I195 VanDerWaalsContact C-N 3.34Å; A193-I195 PolarHBondContact O-N 3.39Å; I195-E197 VanDerWaalsContact C-N 3.33Å; I195-E197 PolarHBondContact O-N 3Å; I195-K198 PolarHBondContact O-N 3.49Å; I195-V199 HydrophobicContact CG2-CG2 4.22Å; I195-V199 WeakPolarHBondContact O-CB 3.29Å; I195-V199 WeakPolarHBondContact O-CG2 3.41Å; I195-V199 PolarHBondContact O-N 2.95Å
196L97.9Very high96.1Very high15 Ų1555.8 Ų55.88%0.07929%0.285CS..Hα-helixtrans-60-44.2178.3174.662.4000111.3K192 A193 E194 V199 K200 Y216 K219 K220 V223 Q224K192-L196 WeakPolarHBondContact O-CB 3.47Å; K192-L196 PolarHBondContact O-N 3.19Å; A193-L196 PolarHBondContact O-N 3.07Å; E194-L196 PolarHBondContact O-N 3.41Å; L196-V199 PolarHBondContact O-N 3.39Å; L196-K200 VanDerWaalsContact O-CB 3.31Å; L196-K200 WeakPolarHBondContact O-CB 3.45Å; L196-K200 PolarHBondContact O-N 3.45Å; L196-Y216 HydrophobicContact CD1-CD2 4.01Å; L196-Y216 HydrophobicContact CD1-CE2 3.9Å; L196-K219 HydrophobicContact CD1-CB 3.73Å; L196-K220 HydrophobicContact CD1-CG 4.07Å; L196-V223 HydrophobicContact CB-CG2 4.34Å; L196-V223 HydrophobicContact CD2-CB 4.05Å; L196-V223 HydrophobicContact CD2-CG1 3.99Å; L196-Q224 VanDerWaalsContact CD2-CD 3.5Å; L196-Q224 HydrophobicContact CD2-CG 3.85Å
197E98.1Very high96.5Very high99 Ų9955 Ų5546%0.46329%0.289SS..Hα-helixtrans-58.9-50.7177.7-171-150.3135.300111.2A193 E194 I195 V199 K200 T201A193-E197 PolarHBondContact O-N 2.87Å; E194-E197 PolarHBondContact O-N 3.22Å; I195-E197 VanDerWaalsContact C-N 3.33Å; I195-E197 PolarHBondContact O-N 3Å; E197-V199 VanDerWaalsContact C-N 3.35Å; E197-V199 PolarHBondContact O-N 3.04Å; E197-K200 WeakPolarHBondContact O-CB 3.44Å; E197-K200 PolarHBondContact O-N 3.21Å; E197-T201 PolarHBondContact O-N 3.27Å; E197-T201 PolarHBondContact O-OG1 3.3Å; E197-T201 VanDerWaalsContact O-OG1 3.12Å
198K98Very high96.6Very high59 Ų5960.6 Ų60.626%0.25732%0.318SS..Hα-helixtrans-67.6-34.7-179.2-59.8-54172.2-152.10113M178 E194 I195 A202M178-K198 HydrophobicContact CE-CG 4.02Å; M178-K198 HydrophobicContact SD-CB 3.91Å; M178-K198 HydrophobicContact SD-CG 3.71Å; E194-K198 WeakPolarHBondContact O-CG 3.22Å; E194-K198 PolarHBondContact O-N 2.93Å; I195-K198 PolarHBondContact O-N 3.49Å; K198-A202 WeakPolarHBondContact O-CB 3.43Å; K198-A202 PolarHBondContact O-N 3.1Å
199V98.3Very high96.7Very high0 Ų058.9 Ų58.90%031%0.307CS..Hα-helixtrans-65.8-41.8172.91700000110.9A175 I195 L196 E197 A202 A203 L215 Y216 K219A175-V199 HydrophobicContact CB-CG2 3.96Å; I195-V199 HydrophobicContact CG2-CG2 4.22Å; I195-V199 WeakPolarHBondContact O-CB 3.29Å; I195-V199 WeakPolarHBondContact O-CG2 3.41Å; I195-V199 PolarHBondContact O-N 2.95Å; L196-V199 PolarHBondContact O-N 3.39Å; E197-V199 VanDerWaalsContact C-N 3.35Å; E197-V199 PolarHBondContact O-N 3.04Å; V199-A202 PolarHBondContact O-N 3.41Å; V199-A203 WeakPolarHBondContact O-CB 3.47Å; V199-A203 PolarHBondContact O-N 2.94Å; V199-L215 HydrophobicContact CG1-CB 4.39Å; V199-L215 HydrophobicContact CG1-CD2 4.25Å; V199-L215 HydrophobicContact CG1-CG 3.83Å; V199-L215 HydrophobicContact CG2-CD2 4.03Å; V199-L215 HydrophobicContact CG2-CG 4.18Å; V199-Y216 VanDerWaalsContact CG1-CA 3.42Å; V199-Y216 HydrophobicContact CG1-CD2 4.29Å; V199-K219 HydrophobicContact CG1-CG 4.39Å; V199-K219 HydrophobicContact CG2-CG 4.37Å
200K98.3Very high96.7Very high85 Ų8554.5 Ų54.537%0.3728%0.278SS..Hα-helixtrans-59.8-52.5175.2178.4-179.1170-176.70110.8L196 E197 A202 A203 E204 Y216L196-K200 VanDerWaalsContact O-CB 3.31Å; L196-K200 WeakPolarHBondContact O-CB 3.45Å; L196-K200 PolarHBondContact O-N 3.45Å; E197-K200 WeakPolarHBondContact O-CB 3.44Å; E197-K200 PolarHBondContact O-N 3.21Å; K200-A202 VanDerWaalsContact C-N 3.31Å; K200-A202 PolarHBondContact O-N 3.29Å; K200-A203 PolarHBondContact O-N 3.38Å; K200-E204 WeakPolarHBondContact CE-OE1 3.44Å; K200-E204 HydrophobicContact CG-CG 4.39Å; K200-E204 IonicContact NZ-OE1 2.91Å; K200-E204 WeakPolarHBondContact O-CG 3.31Å; K200-E204 PolarHBondContact O-N 3.11Å; K200-Y216 HydrophobicContact CB-CD2 3.98Å; K200-Y216 HydrophobicContact CB-CE2 3.53Å; K200-Y216 HydrophobicContact CD-CE2 4.29Å; K200-Y216 HydrophobicContact CG-CE2 3.78Å
201T97.8Very high96.7Very high42 Ų4249.6 Ų49.626%0.25826%0.255SS..Hα-helixtrans-54.4-47.2177.9-58.40000111.4E197 A203 E204 I205E197-T201 PolarHBondContact O-N 3.27Å; E197-T201 PolarHBondContact O-OG1 3.3Å; E197-T201 VanDerWaalsContact O-OG1 3.12Å; T201-A203 PolarHBondContact O-N 2.85Å; T201-E204 PolarHBondContact O-N 3.49Å; T201-I205 HydrophobicContact CG2-CD1 3.79Å; T201-I205 VanDerWaalsContact O-CG1 3.29Å; T201-I205 WeakPolarHBondContact O-CG1 3.44Å; T201-I205 PolarHBondContact O-N 3.23Å
202A98Very high96.8Very high1 Ų145.5 Ų45.51%0.00824%0.236CC..Hα-helixtrans-61.9-41.5177.500000112.6H171 A175 K198 V199 K200 E204 I205 D206 L212H171-A202 HydrophobicContact CB-CB 4Å; A175-A202 HydrophobicContact CB-CB 3.94Å; K198-A202 WeakPolarHBondContact O-CB 3.43Å; K198-A202 PolarHBondContact O-N 3.1Å; V199-A202 PolarHBondContact O-N 3.41Å; K200-A202 VanDerWaalsContact C-N 3.31Å; K200-A202 PolarHBondContact O-N 3.29Å; A202-E204 VanDerWaalsContact C-N 3.34Å; A202-I205 PolarHBondContact O-N 3.33Å; A202-D206 PolarHBondContact O-N 2.96Å; A202-L212 HydrophobicContact CB-CD1 4.15Å; A202-L212 HydrophobicContact CB-CD2 3.84Å
203A97.8Very high96.9Very high4 Ų445 Ų453%0.03323%0.234CC..Hα-helixtrans-68.7-29.617800000113.3V199 K200 T201 D206 P207 L212 Q213 Y216V199-A203 WeakPolarHBondContact O-CB 3.47Å; V199-A203 PolarHBondContact O-N 2.94Å; K200-A203 PolarHBondContact O-N 3.38Å; T201-A203 PolarHBondContact O-N 2.85Å; A203-D206 CarbonylContact O-C 3.51Å; A203-P207 WeakPolarHBondContact O-CA 3.4Å; A203-L212 HydrophobicContact CB-CB 4.32Å; A203-Q213 PolarHBondContact O-NE2 3.46Å; A203-Y216 HydrophobicContact CB-CD1 4.26Å; A203-Y216 HydrophobicContact CB-CG 4.21Å
204E97.6Very high96.9Very high119 Ų11942.6 Ų42.656%0.55622%0.215SC*.Hα-helixtrans-75.2-37.3174.1-72172.8160.200111.8K200 T201 A202K200-E204 WeakPolarHBondContact CE-OE1 3.44Å; K200-E204 HydrophobicContact CG-CG 4.39Å; K200-E204 IonicContact NZ-OE1 2.91Å; K200-E204 WeakPolarHBondContact O-CG 3.31Å; K200-E204 PolarHBondContact O-N 3.11Å; T201-E204 PolarHBondContact O-N 3.49Å; A202-E204 VanDerWaalsContact C-N 3.34Å
205I96Very high96.9Very high59 Ų5939.2 Ų39.230%0.30320%0.199SC..Hα-helixtrans-68.8-36.8176.4-69.7170.4000111.6K168 H171 T201 A202K168-I205 HydrophobicContact CB-CG2 3.63Å; H171-I205 HydrophobicContact CB-CD1 4.38Å; H171-I205 WeakPolarHBondContact CD2-CD1 3.34Å; H171-I205 WeakPolarHBondContact NE2-CD1 3.48Å; T201-I205 HydrophobicContact CG2-CD1 3.79Å; T201-I205 VanDerWaalsContact O-CG1 3.29Å; T201-I205 WeakPolarHBondContact O-CG1 3.44Å; T201-I205 PolarHBondContact O-N 3.23Å; A202-I205 PolarHBondContact O-N 3.33Å
206D95.3Very high97Very high35 Ų3541 Ų4119%0.18721%0.205CC..  trans-12578.9175.7-161.5-16.9000112.2A202 A203 N208 D209 L212 Q213A202-D206 PolarHBondContact O-N 2.96Å; A203-D206 CarbonylContact O-C 3.51Å; D206-N208 PolarHBondContact O-N 3.13Å; D206-D209 HydrophobicContact CB-CB 4.11Å; D206-D209 PolarHBondContact O-N 2.59Å; D206-D209 PolarHBondContact OD1-N 3.17Å; D206-L212 HydrophobicContact CB-CD1 4.17Å; D206-Q213 PolarHBondContact O-NE2 3.17Å
207P95.3Very high97Very high74 Ų7440.5 Ų40.548%0.48120%0.203SC..THydrogen-bonded Turntrans-67.6-17.6-175.126.3-34.5000113.7A203A203-P207 WeakPolarHBondContact O-CA 3.4Å
208N93.2Very high96.9Very high124 Ų12436 Ų3666%0.66318%0.182SC*.THydrogen-bonded Turntrans-90.4-12.8-179.3-71.2-45.1000113.1D206 L210D206-N208 PolarHBondContact O-N 3.13Å; N208-L210 PolarHBondContact O-N 3.13Å; N208-L210 VanDerWaalsContact O-N 3.07Å
209D94.8Very high96.9Very high23 Ų2333.7 Ų33.712%0.12317%0.172CC..  trans-7499.4178.5-170.6-55.8000111.3K172 D206 F211 L212 Q213K172-D209 VanDerWaalsContact CE-OD2 3.3Å; K172-D209 WeakPolarHBondContact CE-OD2 3.42Å; K172-D209 IonicContact NZ-OD1 3.72Å; K172-D209 IonicContact NZ-OD2 3.01Å; K172-D209 PolarHBondContact NZ-OD2 3.17Å; D206-D209 HydrophobicContact CB-CB 4.11Å; D206-D209 PolarHBondContact O-N 2.59Å; D206-D209 PolarHBondContact OD1-N 3.17Å; D209-F211 PolarHBondContact O-N 3.32Å; D209-F211 VanDerWaalsContact O-N 3.13Å; D209-F211 WeakPolarHBondContact OD1-CA 3.48Å; D209-F211 WeakPolarHBondContact OD1-CB 3.33Å; D209-F211 PolarHBondContact OD1-N 3.35Å; D209-L212 HydrophobicContact CB-CB 4.12Å; D209-L212 HydrophobicContact CB-CD1 4Å; D209-L212 HydrophobicContact CB-CG 4.26Å; D209-L212 PolarHBondContact O-N 2.9Å; D209-L212 PolarHBondContact OD1-N 2.62Å; D209-Q213 WeakPolarHBondContact O-CG 3.42Å; D209-Q213 PolarHBondContact O-N 3.35Å
210L95.4Very high96.8Very high5 Ų534.4 Ų34.43%0.02618%0.175CC..Hα-helixtrans-58.1-27.4-179.9-67.6-177.8000113.7N208 S214 L235 K238 N244 V246N208-L210 PolarHBondContact O-N 3.13Å; N208-L210 VanDerWaalsContact O-N 3.07Å; L210-S214 WeakPolarHBondContact O-CB 3.35Å; L210-S214 PolarHBondContact O-N 3.38Å; L210-S214 PolarHBondContact O-OG 2.93Å; L210-L235 HydrophobicContact CD2-CD2 4.2Å; L210-K238 HydrophobicContact CD2-CB 4.46Å; L210-K238 HydrophobicContact CD2-CD 3.64Å; L210-K238 HydrophobicContact CD2-CG 3.92Å; L210-N244 HydrophobicContact CD1-CB 3.97Å; L210-V246 HydrophobicContact CB-CG2 4.3Å
211F95.3Very high96.6Very high30 Ų3033.4 Ų33.413%0.13217%0.171CC..Hα-helixtrans-69.4-46.9176.4172-74.5000110.3I176 D209 S214 L215 V246 Y250I176-F211 HydrophobicContact CD1-CD1 4.44Å; I176-F211 HydrophobicContact CD1-CE1 3.55Å; I176-F211 HydrophobicContact CD1-CZ 3.67Å; I176-F211 HydrophobicContact CG1-CE1 3.37Å; I176-F211 HydrophobicContact CG1-CZ 3.59Å; D209-F211 PolarHBondContact O-N 3.32Å; D209-F211 VanDerWaalsContact O-N 3.13Å; D209-F211 WeakPolarHBondContact OD1-CA 3.48Å; D209-F211 WeakPolarHBondContact OD1-CB 3.33Å; D209-F211 PolarHBondContact OD1-N 3.35Å; F211-S214 PolarHBondContact O-N 2.86Å; F211-L215 HydrophobicContact CE1-CD2 4.2Å; F211-L215 WeakPolarHBondContact O-CB 3.16Å; F211-L215 PolarHBondContact O-N 3.29Å; F211-V246 HydrophobicContact CB-CB 4.31Å; F211-V246 HydrophobicContact CB-CG2 3.91Å; F211-V246 WeakPolarHBondContact CD2-O 3.24Å; F211-Y250 HydrophobicContact CD1-CE2 4.14Å; F211-Y250 AromaticContact CD2-CE2 3.73Å; F211-Y250 HydrophobicContact CD2-CE2 3.73Å; F211-Y250 AromaticContact CE1-CE2 3.84Å; F211-Y250 HydrophobicContact CE1-CE2 3.84Å; F211-Y250 AromaticContact CE2-CE2 3.44Å; F211-Y250 HydrophobicContact CE2-CE2 3.44Å; F211-Y250 VanDerWaalsContact CE2-CE2 3.44Å; F211-Y250 AromaticContact CE2-CZ 3.86Å; F211-Y250 WeakPolarHBondContact CE2-OH 3.19Å; F211-Y250 HydrophobicContact CG-CE2 4.07Å; F211-Y250 AromaticContact CZ-CE2 3.52Å; F211-Y250 HydrophobicContact CZ-CE2 3.52Å; F211-Y250 AromaticContact CZ-CZ 3.67Å; F211-Y250 WeakPolarHBondContact CZ-OH 3.49Å
212L97.5Very high96.5Very high1 Ų134.4 Ų34.41%0.00517%0.172CC..Hα-helixtrans-66.5-43.6178.6-75.3173.9000111.7K172 A175 A202 A203 D206 D209 S214 L215 Y216K172-L212 HydrophobicContact CB-CD1 4.04Å; K172-L212 HydrophobicContact CB-CD2 4.39Å; K172-L212 HydrophobicContact CD-CD1 4.31Å; K172-L212 HydrophobicContact CD-CG 4.47Å; K172-L212 HydrophobicContact CG-CD1 4.03Å; K172-L212 HydrophobicContact CG-CD2 4.02Å; K172-L212 HydrophobicContact CG-CG 4.07Å; A175-L212 HydrophobicContact CB-CD2 4.25Å; A202-L212 HydrophobicContact CB-CD1 4.15Å; A202-L212 HydrophobicContact CB-CD2 3.84Å; A203-L212 HydrophobicContact CB-CB 4.32Å; D206-L212 HydrophobicContact CB-CD1 4.17Å; D209-L212 HydrophobicContact CB-CB 4.12Å; D209-L212 HydrophobicContact CB-CD1 4Å; D209-L212 HydrophobicContact CB-CG 4.26Å; D209-L212 PolarHBondContact O-N 2.9Å; D209-L212 PolarHBondContact OD1-N 2.62Å; L212-S214 PolarHBondContact O-N 2.89Å; L212-L215 PolarHBondContact O-N 2.85Å; L212-Y216 WeakPolarHBondContact O-CB 3.41Å; L212-Y216 PolarHBondContact O-N 2.61Å
213Q98.2Very high96.3Very high40 Ų4036.5 Ų36.519%0.18719%0.185CC..Hα-helixtrans-59-48.4175.4-61.6-50-52.900110.8A203 D206 D209 L215 Y216 V217 L235A203-Q213 PolarHBondContact O-NE2 3.46Å; D206-Q213 PolarHBondContact O-NE2 3.17Å; D209-Q213 WeakPolarHBondContact O-CG 3.42Å; D209-Q213 PolarHBondContact O-N 3.35Å; Q213-L215 VanDerWaalsContact C-N 3.34Å; Q213-L215 PolarHBondContact O-N 3.11Å; Q213-Y216 PolarHBondContact O-N 2.9Å; Q213-V217 VanDerWaalsContact O-CG2 3.31Å; Q213-V217 WeakPolarHBondContact O-CG2 3.22Å; Q213-V217 PolarHBondContact O-N 3.4Å; Q213-L235 HydrophobicContact CB-CD1 4.4Å; Q213-L235 HydrophobicContact CB-CD2 3.71Å
214S97.9Very high96.1Very high0 Ų041.3 Ų41.30%021%0.207CC..Hα-helixtrans-64.6-37.4179.6-56.10000112.9L210 F211 L212 L218 G247L210-S214 WeakPolarHBondContact O-CB 3.35Å; L210-S214 PolarHBondContact O-N 3.38Å; L210-S214 PolarHBondContact O-OG 2.93Å; F211-S214 PolarHBondContact O-N 2.86Å; L212-S214 PolarHBondContact O-N 2.89Å; S214-L218 WeakPolarHBondContact O-CB 3.41Å; S214-L218 PolarHBondContact O-N 3.3Å; S214-G247 WeakPolarHBondContact CB-O 3.39Å
215L97.8Very high95.8Very high1 Ų138.5 Ų38.51%0.00521%0.21CC..Hα-helixtrans-65.6-44.8174.4178.757.1000111.1V199 F211 L212 Q213 L218 K219 Y250V199-L215 HydrophobicContact CG1-CB 4.39Å; V199-L215 HydrophobicContact CG1-CD2 4.25Å; V199-L215 HydrophobicContact CG1-CG 3.83Å; V199-L215 HydrophobicContact CG2-CD2 4.03Å; V199-L215 HydrophobicContact CG2-CG 4.18Å; F211-L215 HydrophobicContact CE1-CD2 4.2Å; F211-L215 WeakPolarHBondContact O-CB 3.16Å; F211-L215 PolarHBondContact O-N 3.29Å; L212-L215 PolarHBondContact O-N 2.85Å; Q213-L215 VanDerWaalsContact C-N 3.34Å; Q213-L215 PolarHBondContact O-N 3.11Å; L215-L218 PolarHBondContact O-N 3.22Å; L215-K219 HydrophobicContact CD1-CD 4.46Å; L215-K219 HydrophobicContact CD1-CG 4.08Å; L215-K219 HydrophobicContact CG-CG 4.47Å; L215-K219 WeakPolarHBondContact O-CG 3.44Å; L215-K219 PolarHBondContact O-N 3.2Å; L215-Y250 HydrophobicContact CB-CD2 3.87Å; L215-Y250 HydrophobicContact CB-CE2 3.8Å; L215-Y250 HydrophobicContact CB-CG 4.31Å; L215-Y250 HydrophobicContact CD1-CD1 3.94Å; L215-Y250 HydrophobicContact CD1-CE1 3.66Å; L215-Y250 HydrophobicContact CD1-CE2 4.26Å; L215-Y250 HydrophobicContact CD1-CG 4.38Å; L215-Y250 HydrophobicContact CG-CE2 4.42Å
216Y98.2Very high95.6Very high45 Ų4539.4 Ų39.418%0.17621%0.213CC..Hα-helixtrans-60.5-50.1179.6175.7-133.7000112L196 V199 K200 A203 L212 Q213 L218 K219 K220L196-Y216 HydrophobicContact CD1-CD2 4.01Å; L196-Y216 HydrophobicContact CD1-CE2 3.9Å; V199-Y216 VanDerWaalsContact CG1-CA 3.42Å; V199-Y216 HydrophobicContact CG1-CD2 4.29Å; K200-Y216 HydrophobicContact CB-CD2 3.98Å; K200-Y216 HydrophobicContact CB-CE2 3.53Å; K200-Y216 HydrophobicContact CD-CE2 4.29Å; K200-Y216 HydrophobicContact CG-CE2 3.78Å; A203-Y216 HydrophobicContact CB-CD1 4.26Å; A203-Y216 HydrophobicContact CB-CG 4.21Å; L212-Y216 WeakPolarHBondContact O-CB 3.41Å; L212-Y216 PolarHBondContact O-N 2.61Å; Q213-Y216 PolarHBondContact O-N 2.9Å; Y216-L218 VanDerWaalsContact C-N 3.31Å; Y216-L218 PolarHBondContact O-N 2.95Å; Y216-K219 PolarHBondContact O-N 3.14Å; Y216-K220 HydrophobicContact CD2-CG 4.06Å; Y216-K220 HydrophobicContact CE1-CD 4.02Å; Y216-K220 HydrophobicContact CE2-CD 3.86Å; Y216-K220 HydrophobicContact CE2-CG 3.62Å; Y216-K220 PolarHBondContact O-N 3.33Å
217V97.9Very high95.5Very high4 Ų444.2 Ų44.22%0.02424%0.238CC..Hα-helixtrans-59.6-42.1178.7-178.80000111.5Q213 K219 K220 F221 V228 E231 I232 L235Q213-V217 VanDerWaalsContact O-CG2 3.31Å; Q213-V217 WeakPolarHBondContact O-CG2 3.22Å; Q213-V217 PolarHBondContact O-N 3.4Å; V217-K219 PolarHBondContact O-N 3.42Å; V217-K220 PolarHBondContact O-N 3.02Å; V217-F221 PolarHBondContact O-N 3.46Å; V217-V228 HydrophobicContact CG1-CB 3.47Å; V217-V228 VanDerWaalsContact CG1-CB 3.47Å; V217-V228 HydrophobicContact CG1-CG1 3.9Å; V217-V228 HydrophobicContact CG1-CG2 3.78Å; V217-E231 HydrophobicContact CG1-CB 3.87Å; V217-E231 HydrophobicContact CG2-CB 4.15Å; V217-E231 VanDerWaalsContact CG2-OE2 3.24Å; V217-E231 WeakPolarHBondContact CG2-OE2 3.21Å; V217-I232 HydrophobicContact CB-CD1 4.06Å; V217-I232 HydrophobicContact CG1-CD1 3.5Å; V217-I232 HydrophobicContact CG1-CG1 3.67Å; V217-L235 HydrophobicContact CB-CD1 4.2Å; V217-L235 HydrophobicContact CG2-CD1 3.73Å
218L96.9Very high95.5Very high5 Ų540.7 Ų40.73%0.02622%0.216CC..Hα-helixtrans-61.2-42.9173.5177.366000111.9S214 L215 Y216 F221 E222 Y250 E253S214-L218 WeakPolarHBondContact O-CB 3.41Å; S214-L218 PolarHBondContact O-N 3.3Å; L215-L218 PolarHBondContact O-N 3.22Å; Y216-L218 VanDerWaalsContact C-N 3.31Å; Y216-L218 PolarHBondContact O-N 2.95Å; L218-F221 HydrophobicContact CD1-CD1 4.46Å; L218-F221 WeakPolarHBondContact O-CB 3.43Å; L218-F221 PolarHBondContact O-N 3.42Å; L218-E222 HydrophobicContact CD1-CG 4.11Å; L218-E222 HydrophobicContact CG-CG 4.29Å; L218-E222 WeakPolarHBondContact O-CG 3.19Å; L218-E222 PolarHBondContact O-N 2.08Å; L218-Y250 HydrophobicContact CD2-CD1 3.74Å; L218-Y250 HydrophobicContact CD2-CG 4.26Å; L218-E253 HydrophobicContact CD1-CB 4.31Å; L218-E253 HydrophobicContact CD2-CB 3.95Å
219K96.8Very high95.6Very high11 Ų1137.1 Ų37.15%0.04820%0.197CC..Hα-helixtrans-68-36180-67.6-46.7-179.1-178.30113W184 L196 V199 L215 Y216 V217 F221 E222 V223W184-K219 HydrophobicContact CH2-CD 4.06Å; W184-K219 HydrophobicContact CZ2-CD 4.42Å; W184-K219 HydrophobicContact CZ3-CD 4.44Å; L196-K219 HydrophobicContact CD1-CB 3.73Å; V199-K219 HydrophobicContact CG1-CG 4.39Å; V199-K219 HydrophobicContact CG2-CG 4.37Å; L215-K219 HydrophobicContact CD1-CD 4.46Å; L215-K219 HydrophobicContact CD1-CG 4.08Å; L215-K219 HydrophobicContact CG-CG 4.47Å; L215-K219 WeakPolarHBondContact O-CG 3.44Å; L215-K219 PolarHBondContact O-N 3.2Å; Y216-K219 PolarHBondContact O-N 3.14Å; V217-K219 PolarHBondContact O-N 3.42Å; K219-F221 VanDerWaalsContact C-N 3.34Å; K219-F221 PolarHBondContact O-N 3.34Å; K219-E222 VanDerWaalsContact CD-OE2 3.25Å; K219-E222 WeakPolarHBondContact CD-OE2 3.14Å; K219-E222 WeakPolarHBondContact CE-OE2 3.41Å; K219-E222 IonicContact NZ-OE2 3.23Å; K219-E222 PolarHBondContact NZ-OE2 3.46Å; K219-E222 PolarHBondContact O-N 3.1Å; K219-V223 WeakPolarHBondContact O-CB 3.2Å; K219-V223 VanDerWaalsContact O-CG2 3.28Å; K219-V223 WeakPolarHBondContact O-CG2 3.45Å; K219-V223 PolarHBondContact O-N 2.94Å
220K96.4Very high95.6Very high14 Ų1444.3 Ų44.36%0.06123%0.229CC..Hα-helixtrans-57.4-48.8170.5-69.4-167.7-65.21620111.1L196 Y216 V217 E222 Q224 G225 E226 V228 E231L196-K220 HydrophobicContact CD1-CG 4.07Å; Y216-K220 HydrophobicContact CD2-CG 4.06Å; Y216-K220 HydrophobicContact CE1-CD 4.02Å; Y216-K220 HydrophobicContact CE2-CD 3.86Å; Y216-K220 HydrophobicContact CE2-CG 3.62Å; Y216-K220 PolarHBondContact O-N 3.33Å; V217-K220 PolarHBondContact O-N 3.02Å; K220-E222 PolarHBondContact O-N 2.85Å; K220-Q224 WeakPolarHBondContact O-CA 3.26Å; K220-Q224 WeakPolarHBondContact O-CB 3.37Å; K220-Q224 PolarHBondContact O-N 2.73Å; K220-G225 PolarHBondContact O-N 3.28Å; K220-E226 IonicContact NZ-OE2 3.66Å; K220-V228 HydrophobicContact CB-CG1 4.35Å; K220-E231 WeakPolarHBondContact CE-OE2 3.32Å; K220-E231 IonicContact NZ-OE1 3.5Å; K220-E231 PolarHBondContact NZ-OE1 3.25Å; K220-E231 IonicContact NZ-OE2 3.92Å; K220-E231 PolarHBondContact NZ-OE2 2.95Å
221F95.4Very high95.7Very high65 Ų6547.8 Ų47.829%0.28525%0.245SC..Hα-helixtrans-58.6-49.4175.6170.6-106.8000112.5V217 L218 K219 V223 G225 V228 Y254V217-F221 PolarHBondContact O-N 3.46Å; L218-F221 HydrophobicContact CD1-CD1 4.46Å; L218-F221 WeakPolarHBondContact O-CB 3.43Å; L218-F221 PolarHBondContact O-N 3.42Å; K219-F221 VanDerWaalsContact C-N 3.34Å; K219-F221 PolarHBondContact O-N 3.34Å; F221-V223 PolarHBondContact O-N 3.03Å; F221-G225 WeakPolarHBondContact O-CA 3.42Å; F221-G225 PolarHBondContact O-N 3.34Å; F221-G225 VanDerWaalsContact O-N 3.1Å; F221-V228 HydrophobicContact CB-CG2 3.78Å; F221-V228 HydrophobicContact CG-CG2 4.43Å; F221-Y254 HydrophobicContact CB-CD2 4.29Å; F221-Y254 HydrophobicContact CB-CE2 4.45Å; F221-Y254 AromaticContact CD1-CD2 3.86Å; F221-Y254 HydrophobicContact CD1-CD2 3.86Å; F221-Y254 HydrophobicContact CD1-CE2 4.31Å; F221-Y254 HydrophobicContact CD2-CD2 4.19Å; F221-Y254 AromaticContact CD2-CE2 3.8Å; F221-Y254 HydrophobicContact CD2-CE2 3.8Å; F221-Y254 HydrophobicContact CE1-CD2 4.21Å; F221-Y254 HydrophobicContact CE2-CE2 4.07Å; F221-Y254 AromaticContact CG-CD2 3.84Å; F221-Y254 HydrophobicContact CG-CD2 3.84Å; F221-Y254 AromaticContact CG-CE2 3.92Å; F221-Y254 HydrophobicContact CG-CE2 3.92Å; F221-Y254 HydrophobicContact CZ-CE2 4.44Å
222E93.9Very high95.8Very high62 Ų6246.3 Ų46.329%0.2924%0.239SC..Hα-helixtrans-70-27.2-175.1-72.4-179.3153.900114.5W184 L218 K219 K220W184-E222 HydrophobicContact CZ2-CB 3.76Å; L218-E222 HydrophobicContact CD1-CG 4.11Å; L218-E222 HydrophobicContact CG-CG 4.29Å; L218-E222 WeakPolarHBondContact O-CG 3.19Å; L218-E222 PolarHBondContact O-N 2.08Å; K219-E222 VanDerWaalsContact CD-OE2 3.25Å; K219-E222 WeakPolarHBondContact CD-OE2 3.14Å; K219-E222 WeakPolarHBondContact CE-OE2 3.41Å; K219-E222 IonicContact NZ-OE2 3.23Å; K219-E222 PolarHBondContact NZ-OE2 3.46Å; K219-E222 PolarHBondContact O-N 3.1Å; K220-E222 PolarHBondContact O-N 2.85Å
223V95Very high95.8Very high46 Ų4648.4 Ų48.428%0.27925%0.249SC..Hα-helixtrans-103.4-43.4-174.31800000112W184 K192 L196 K219 F221W184-V223 HydrophobicContact CH2-CG2 3.59Å; W184-V223 HydrophobicContact CZ2-CG2 3.54Å; K192-V223 HydrophobicContact CB-CG1 4.42Å; K192-V223 HydrophobicContact CB-CG2 4.02Å; L196-V223 HydrophobicContact CB-CG2 4.34Å; L196-V223 HydrophobicContact CD2-CB 4.05Å; L196-V223 HydrophobicContact CD2-CG1 3.99Å; K219-V223 WeakPolarHBondContact O-CB 3.2Å; K219-V223 VanDerWaalsContact O-CG2 3.28Å; K219-V223 WeakPolarHBondContact O-CG2 3.45Å; K219-V223 PolarHBondContact O-N 2.94Å; F221-V223 PolarHBondContact O-N 3.03Å
224Q93.6Very high95.7Very high104 Ų10450 Ų5049%0.48626%0.264SS..Hα-helixtrans-104.7-13.8-172.4-61.1166.5-54.500112.6L196 K220 E226L196-Q224 VanDerWaalsContact CD2-CD 3.5Å; L196-Q224 HydrophobicContact CD2-CG 3.85Å; K220-Q224 WeakPolarHBondContact O-CA 3.26Å; K220-Q224 WeakPolarHBondContact O-CB 3.37Å; K220-Q224 PolarHBondContact O-N 2.73Å; Q224-E226 HydrophobicContact CB-CG 3.92Å; Q224-E226 PolarHBondContact O-N 3.45Å; Q224-E226 PolarHBondContact OE1-OE1 3.26Å
225G91.2Very high95.7Very high60 Ų6050.9 Ų50.962%0.61927%0.269SS*.  trans69.119.9-17700000113.7K220 F221K220-G225 PolarHBondContact O-N 3.28Å; F221-G225 WeakPolarHBondContact O-CA 3.42Å; F221-G225 PolarHBondContact O-N 3.34Å; F221-G225 VanDerWaalsContact O-N 3.1Å
226E91.5Very high95.7Very high79 Ų7951 Ų5137%0.36927%0.269SS..  trans-63.6144.5179.7-71.4-176.3-168.200111.8K220 Q224 V228K220-E226 IonicContact NZ-OE2 3.66Å; Q224-E226 HydrophobicContact CB-CG 3.92Å; Q224-E226 PolarHBondContact O-N 3.45Å; Q224-E226 PolarHBondContact OE1-OE1 3.26Å; E226-V228 HydrophobicContact CB-CG1 4.12Å; E226-V228 PolarHBondContact O-N 2.94Å
227N92.6Very high95.6Very high135 Ų13555.7 Ų55.772%0.72229%0.291SS*.  trans-76.4105.8170.1-176-2.2000109.5D229N227-D229 PolarHBondContact OD1-N 3.23Å
228V95.9Very high95.5Very high1 Ų159.5 Ų59.51%0.00631%0.307CS..  trans-112.515.3-177.4-61.50000113.5V217 K220 F221 E226 E230 E231 I232 Y254V217-V228 HydrophobicContact CG1-CB 3.47Å; V217-V228 VanDerWaalsContact CG1-CB 3.47Å; V217-V228 HydrophobicContact CG1-CG1 3.9Å; V217-V228 HydrophobicContact CG1-CG2 3.78Å; K220-V228 HydrophobicContact CB-CG1 4.35Å; F221-V228 HydrophobicContact CB-CG2 3.78Å; F221-V228 HydrophobicContact CG-CG2 4.43Å; E226-V228 HydrophobicContact CB-CG1 4.12Å; E226-V228 PolarHBondContact O-N 2.94Å; V228-E230 VanDerWaalsContact C-N 3.3Å; V228-E230 PolarHBondContact O-N 3.23Å; V228-E231 PolarHBondContact O-N 3.31Å; V228-I232 HydrophobicContact CB-CG1 4.47Å; V228-I232 HydrophobicContact CG2-CG1 3.94Å; V228-I232 WeakPolarHBondContact O-CG1 3.38Å; V228-I232 PolarHBondContact O-N 2.97Å; V228-Y254 HydrophobicContact CG2-CD2 3.84Å; V228-Y254 HydrophobicContact CG2-CE2 3.42Å; V228-Y254 VanDerWaalsContact CG2-CE2 3.42Å
229D94.7Very high95.4Very high49 Ų4959.3 Ų59.326%0.26231%0.306SS..Hα-helixtrans-55.9-44-174.9-111-37.6000111.5N227 I232 Q233 Y254 R262N227-D229 PolarHBondContact OD1-N 3.23Å; D229-I232 PolarHBondContact O-N 3.42Å; D229-Q233 WeakPolarHBondContact O-CB 3.33Å; D229-Q233 WeakPolarHBondContact O-CG 3.18Å; D229-Q233 PolarHBondContact O-N 2.98Å; D229-Y254 WeakPolarHBondContact CA-OH 3.43Å; D229-Y254 PolarHBondContact N-OH 2.87Å; D229-Y254 WeakPolarHBondContact OD1-CE1 3.41Å; D229-Y254 PolarHBondContact OD1-OH 2.86Å; D229-Y254 PolarHBondContact OD2-OH 3.3Å; D229-R262 IonicContact OD1-CZ 3.5Å; D229-R262 IonicContact OD1-NH1 3.71Å; D229-R262 PolarHBondContact OD1-NH1 2.93Å; D229-R262 IonicContact OD1-NH2 3.82Å; D229-R262 PolarHBondContact OD1-NH2 3.43Å; D229-R262 IonicContact OD2-NH1 2.73Å; D229-R262 PolarHBondContact OD2-NH1 2.9Å; D229-R262 IonicContact OD2-NH2 3.66Å
230E96.4Very high95.3Very high173 Ų17360.6 Ų60.681%0.80831%0.313SS*.Hα-helixtrans-65.1-43.8179.6-66.4-175.5178.500112.6V228 Q233 S234V228-E230 VanDerWaalsContact C-N 3.3Å; V228-E230 PolarHBondContact O-N 3.23Å; E230-Q233 PolarHBondContact O-N 3.23Å; E230-S234 WeakPolarHBondContact O-CB 3.36Å; E230-S234 PolarHBondContact O-N 3.47Å
231E97.6Very high95.3Very high78 Ų7864.7 Ų64.736%0.36434%0.343SS..Hα-helixtrans-63.8-44.8177.9-66.2177.9-139.700111.1V217 K220 V228 S234 L235V217-E231 HydrophobicContact CG1-CB 3.87Å; V217-E231 HydrophobicContact CG2-CB 4.15Å; V217-E231 VanDerWaalsContact CG2-OE2 3.24Å; V217-E231 WeakPolarHBondContact CG2-OE2 3.21Å; K220-E231 WeakPolarHBondContact CE-OE2 3.32Å; K220-E231 IonicContact NZ-OE1 3.5Å; K220-E231 PolarHBondContact NZ-OE1 3.25Å; K220-E231 IonicContact NZ-OE2 3.92Å; K220-E231 PolarHBondContact NZ-OE2 2.95Å; V228-E231 PolarHBondContact O-N 3.31Å; E231-S234 WeakPolarHBondContact O-CB 3.49Å; E231-S234 PolarHBondContact O-N 2.95Å; E231-L235 WeakPolarHBondContact O-CB 3.29Å; E231-L235 VanDerWaalsContact O-CG 3.32Å; E231-L235 WeakPolarHBondContact O-CG 3.39Å; E231-L235 PolarHBondContact O-N 3.47Å
232I97.2Very high95.1Very high0 Ų065.1 Ų65.10%035%0.352CS..Hα-helixtrans-62.3-44.5177-69.2-67.7000111.1V217 V228 D229 S234 L235 L236 I251 Y254 F255V217-I232 HydrophobicContact CB-CD1 4.06Å; V217-I232 HydrophobicContact CG1-CD1 3.5Å; V217-I232 HydrophobicContact CG1-CG1 3.67Å; V228-I232 HydrophobicContact CB-CG1 4.47Å; V228-I232 HydrophobicContact CG2-CG1 3.94Å; V228-I232 WeakPolarHBondContact O-CG1 3.38Å; V228-I232 PolarHBondContact O-N 2.97Å; D229-I232 PolarHBondContact O-N 3.42Å; I232-S234 VanDerWaalsContact C-N 3.34Å; I232-S234 PolarHBondContact O-N 2.92Å; I232-L235 PolarHBondContact O-N 3.49Å; I232-L236 WeakPolarHBondContact O-CB 3.42Å; I232-L236 PolarHBondContact O-N 3.02Å; I232-I251 HydrophobicContact CG2-CG2 3.86Å; I232-Y254 HydrophobicContact CB-CD1 4.07Å; I232-Y254 HydrophobicContact CB-CE1 4.18Å; I232-Y254 HydrophobicContact CD1-CD1 4.45Å; I232-Y254 HydrophobicContact CD1-CG 4.16Å; I232-Y254 HydrophobicContact CG1-CD1 3.8Å; I232-Y254 HydrophobicContact CG1-CD2 4.22Å; I232-Y254 HydrophobicContact CG1-CE1 4.08Å; I232-Y254 HydrophobicContact CG1-CG 3.84Å; I232-Y254 HydrophobicContact CG2-CD1 3.68Å; I232-Y254 HydrophobicContact CG2-CE1 4.12Å; I232-Y254 HydrophobicContact CG2-CG 4.38Å; I232-F255 HydrophobicContact CG2-CE1 4.15Å; I232-F255 HydrophobicContact CG2-CE2 4.13Å; I232-F255 HydrophobicContact CG2-CZ 3.69Å
233Q95.9Very high95Very high44 Ų4465.4 Ų65.421%0.20636%0.364CS..Hα-helixtrans-64.2-39.5177.4-72.1-67.6-24.700111.8D229 E230 L236 K237 F255D229-Q233 WeakPolarHBondContact O-CB 3.33Å; D229-Q233 WeakPolarHBondContact O-CG 3.18Å; D229-Q233 PolarHBondContact O-N 2.98Å; E230-Q233 PolarHBondContact O-N 3.23Å; Q233-L236 PolarHBondContact O-N 3.41Å; Q233-K237 WeakPolarHBondContact O-CG 3.5Å; Q233-K237 PolarHBondContact O-N 3.43Å; Q233-F255 VanDerWaalsContact NE2-CZ 3.34Å
234S97.2Very high94.8Very high74 Ų7466.1 Ų66.152%0.51737%0.367SS..Hα-helixtrans-61.9-46.8174.1-175.80000111.7E230 E231 I232 L236 K237 K238E230-S234 WeakPolarHBondContact O-CB 3.36Å; E230-S234 PolarHBondContact O-N 3.47Å; E231-S234 WeakPolarHBondContact O-CB 3.49Å; E231-S234 PolarHBondContact O-N 2.95Å; I232-S234 VanDerWaalsContact C-N 3.34Å; I232-S234 PolarHBondContact O-N 2.92Å; S234-L236 VanDerWaalsContact C-N 3.34Å; S234-L236 PolarHBondContact O-N 3.43Å; S234-K237 PolarHBondContact O-N 3.27Å; S234-K238 WeakPolarHBondContact O-CB 3.47Å; S234-K238 PolarHBondContact O-N 3.4Å
235L97.6Very high94.7Very high18 Ų1862.4 Ų62.49%0.09435%0.35CS..Hα-helixtrans-63.6-37.8177.2-73.1169.5000112.5L210 Q213 V217 E231 I232 K238 S239 I251L210-L235 HydrophobicContact CD2-CD2 4.2Å; Q213-L235 HydrophobicContact CB-CD1 4.4Å; Q213-L235 HydrophobicContact CB-CD2 3.71Å; V217-L235 HydrophobicContact CB-CD1 4.2Å; V217-L235 HydrophobicContact CG2-CD1 3.73Å; E231-L235 WeakPolarHBondContact O-CB 3.29Å; E231-L235 VanDerWaalsContact O-CG 3.32Å; E231-L235 WeakPolarHBondContact O-CG 3.39Å; E231-L235 PolarHBondContact O-N 3.47Å; I232-L235 PolarHBondContact O-N 3.49Å; L235-K238 PolarHBondContact O-N 3.44Å; L235-S239 WeakPolarHBondContact O-CB 3.24Å; L235-S239 PolarHBondContact O-N 3.32Å; L235-S239 PolarHBondContact O-OG 3.42Å; L235-I251 HydrophobicContact CB-CD1 3.96Å; L235-I251 HydrophobicContact CB-CG1 4.49Å
236L96.9Very high94.6Very high3 Ų363 Ų632%0.01634%0.342CS..Hα-helixtrans-63.7-49.1174.8-18059.5000111.2I232 Q233 S234 K238 S239 I240 L248 I251 F255 E266 V270I232-L236 WeakPolarHBondContact O-CB 3.42Å; I232-L236 PolarHBondContact O-N 3.02Å; Q233-L236 PolarHBondContact O-N 3.41Å; S234-L236 VanDerWaalsContact C-N 3.34Å; S234-L236 PolarHBondContact O-N 3.43Å; L236-K238 VanDerWaalsContact C-N 3.32Å; L236-K238 PolarHBondContact O-N 3.06Å; L236-S239 WeakPolarHBondContact O-CB 3.44Å; L236-S239 PolarHBondContact O-N 3.33Å; L236-I240 HydrophobicContact CD1-CD1 4.14Å; L236-I240 HydrophobicContact CD1-CG1 4.43Å; L236-I240 HydrophobicContact CG-CD1 4.08Å; L236-I240 WeakPolarHBondContact O-CG1 3.33Å; L236-I240 PolarHBondContact O-N 2.92Å; L236-L248 HydrophobicContact CD1-CD1 3.69Å; L236-I251 HydrophobicContact CB-CD1 4.32Å; L236-I251 HydrophobicContact CB-CG2 4.24Å; L236-I251 HydrophobicContact CD1-CG2 4.28Å; L236-F255 HydrophobicContact CD2-CE2 4.2Å; L236-F255 HydrophobicContact CD2-CZ 4.43Å; L236-E266 WeakPolarHBondContact CD2-OE2 3.39Å; L236-V270 HydrophobicContact CD1-CG2 3.8Å
237K96.8Very high94.5Very high144 Ų14459.3 Ų59.363%0.62632%0.324SS*.Hα-helixtrans-58-45176.1-72.4174.3-175179.20111.5Q233 S234 I240 S241Q233-K237 WeakPolarHBondContact O-CG 3.5Å; Q233-K237 PolarHBondContact O-N 3.43Å; S234-K237 PolarHBondContact O-N 3.27Å; K237-I240 PolarHBondContact O-N 3.12Å; K237-S241 WeakPolarHBondContact O-CB 3.34Å; K237-S241 PolarHBondContact O-N 2.92Å; K237-S241 PolarHBondContact O-OG 3.42Å
238K96.6Very high94.6Very high85 Ų8552.9 Ų52.937%0.3729%0.29SS..Hα-helixtrans-64.1-39.8177.5-169.8171.9175.1-174.10112L210 S234 L235 L236 I240 S241 T242L210-K238 HydrophobicContact CD2-CB 4.46Å; L210-K238 HydrophobicContact CD2-CD 3.64Å; L210-K238 HydrophobicContact CD2-CG 3.92Å; S234-K238 WeakPolarHBondContact O-CB 3.47Å; S234-K238 PolarHBondContact O-N 3.4Å; L235-K238 PolarHBondContact O-N 3.44Å; L236-K238 VanDerWaalsContact C-N 3.32Å; L236-K238 PolarHBondContact O-N 3.06Å; K238-I240 VanDerWaalsContact C-N 3.35Å; K238-I240 PolarHBondContact O-N 3.43Å; K238-S241 PolarHBondContact O-N 3.02Å; K238-S241 PolarHBondContact O-OG 3Å; K238-T242 HydrophobicContact CG-CG2 4.42Å; K238-T242 WeakPolarHBondContact O-CB 2.99Å; K238-T242 WeakPolarHBondContact O-CG2 3.44Å; K238-T242 PolarHBondContact O-N 3.49Å; K238-T242 PolarHBondContact O-OG1 3.11Å
239S94.8Very high94.4Very high0 Ų056.6 Ų56.60%031%0.31CS..Hα-helixtrans-62.9-41.6176.4-59.60000111.6L235 L236 A243 N244L235-S239 WeakPolarHBondContact O-CB 3.24Å; L235-S239 PolarHBondContact O-N 3.32Å; L235-S239 PolarHBondContact O-OG 3.42Å; L236-S239 WeakPolarHBondContact O-CB 3.44Å; L236-S239 PolarHBondContact O-N 3.33Å; S239-A243 CarbonylContact O-C 3.58Å; S239-A243 PolarHBondContact O-N 2.91Å; S239-N244 WeakPolarHBondContact CA-O 3.36Å; S239-N244 VanDerWaalsContact CB-O 3.32Å; S239-N244 WeakPolarHBondContact CB-O 3.46Å; S239-N244 PolarHBondContact O-N 2.99Å
240I95.1Very high94.4Very high39 Ų3955.4 Ų55.420%0.230%0.302CS..Hα-helixtrans-68-50.2176.8-65164.3000110.6L236 K237 K238 T242 A243 V270 I273 F274L236-I240 HydrophobicContact CD1-CD1 4.14Å; L236-I240 HydrophobicContact CD1-CG1 4.43Å; L236-I240 HydrophobicContact CG-CD1 4.08Å; L236-I240 WeakPolarHBondContact O-CG1 3.33Å; L236-I240 PolarHBondContact O-N 2.92Å; K237-I240 PolarHBondContact O-N 3.12Å; K238-I240 VanDerWaalsContact C-N 3.35Å; K238-I240 PolarHBondContact O-N 3.43Å; I240-T242 VanDerWaalsContact C-N 3.26Å; I240-T242 PolarHBondContact O-N 3.33Å; I240-A243 PolarHBondContact O-N 3.42Å; I240-A243 VanDerWaalsContact O-N 3.08Å; I240-V270 HydrophobicContact CD1-CG2 3.96Å; I240-V270 HydrophobicContact CG1-CG1 4.45Å; I240-V270 HydrophobicContact CG1-CG2 4.2Å; I240-I273 HydrophobicContact CG2-CD1 3.56Å; I240-F274 HydrophobicContact CG2-CE2 4.24Å
241S94.8Very high94.4Very high99 Ų9947.1 Ų47.169%0.69226%0.263SS*.Hα-helixtrans-65.5-29.7-175.366.70000113.4K237 K238K237-S241 WeakPolarHBondContact O-CB 3.34Å; K237-S241 PolarHBondContact O-N 2.92Å; K237-S241 PolarHBondContact O-OG 3.42Å; K238-S241 PolarHBondContact O-N 3.02Å; K238-S241 PolarHBondContact O-OG 3Å
242T92.4Very high94.2Very high75 Ų7543.5 Ų43.546%0.4625%0.246SC..THydrogen-bonded Turntrans-93.61.4176.860.30000113.5K238 I240 N244K238-T242 HydrophobicContact CG-CG2 4.42Å; K238-T242 WeakPolarHBondContact O-CB 2.99Å; K238-T242 WeakPolarHBondContact O-CG2 3.44Å; K238-T242 PolarHBondContact O-N 3.49Å; K238-T242 PolarHBondContact O-OG1 3.11Å; I240-T242 VanDerWaalsContact C-N 3.26Å; I240-T242 PolarHBondContact O-N 3.33Å; T242-N244 PolarHBondContact O-N 3.43Å; T242-N244 VanDerWaalsContact O-N 3.08Å; T242-N244 WeakPolarHBondContact OG1-CB 3.47Å
243A91.5Very high94Very high67 Ų6747.7 Ų47.755%0.55427%0.266SS*.THydrogen-bonded Turntrans49.729.7-171.400000113.6S239 I240 F274S239-A243 CarbonylContact O-C 3.58Å; S239-A243 PolarHBondContact O-N 2.91Å; I240-A243 PolarHBondContact O-N 3.42Å; I240-A243 VanDerWaalsContact O-N 3.08Å; A243-F274 HydrophobicContact CB-CE1 3.75Å; A243-F274 HydrophobicContact CB-CZ 4.01Å
244N90.3Very high94Very high61 Ų6145.9 Ų45.933%0.32626%0.257SS..  trans-112.595.9-176.6-174.20.3000110.6L210 S239 T242 V246L210-N244 HydrophobicContact CD1-CB 3.97Å; S239-N244 WeakPolarHBondContact CA-O 3.36Å; S239-N244 VanDerWaalsContact CB-O 3.32Å; S239-N244 WeakPolarHBondContact CB-O 3.46Å; S239-N244 PolarHBondContact O-N 2.99Å; T242-N244 PolarHBondContact O-N 3.43Å; T242-N244 VanDerWaalsContact O-N 3.08Å; T242-N244 WeakPolarHBondContact OG1-CB 3.47Å; N244-V246 PolarHBondContact O-N 3.48Å; N244-V246 VanDerWaalsContact OD1-CG1 3.28Å; N244-V246 WeakPolarHBondContact OD1-CG1 3.36Å; N244-V246 WeakPolarHBondContact OD1-CG2 3.45Å; N244-V246 PolarHBondContact OD1-N 2.71Å
245L90.9Very high93.8Very high27 Ų2742.3 Ų42.314%0.14123%0.232CC..  trans-92.713-173-54.5-178.4000114.1G247 L248 V270 F274 L280L245-G247 VanDerWaalsContact C-N 3.3Å; L245-G247 PolarHBondContact O-N 3.49Å; L245-L248 HydrophobicContact CB-CB 4.35Å; L245-L248 HydrophobicContact CB-CD2 4.48Å; L245-L248 WeakPolarHBondContact O-CB 3.4Å; L245-L248 PolarHBondContact O-N 2.87Å; L245-L248 VanDerWaalsContact O-N 3.11Å; L245-V270 HydrophobicContact CD2-CG1 4.1Å; L245-F274 HydrophobicContact CD1-CB 4.37Å; L245-F274 HydrophobicContact CD1-CD2 4.01Å; L245-F274 HydrophobicContact CD1-CG 4.19Å; L245-F274 HydrophobicContact CD2-CD2 4.24Å; L245-F274 HydrophobicContact CD2-CE2 4.07Å; L245-L280 HydrophobicContact CD1-CD1 3.9Å; L245-L280 HydrophobicContact CD1-CG 4.14Å
246V89.2Confident93.5Very high73 Ų7343.6 Ų43.644%0.44224%0.237SC..THydrogen-bonded Turntrans-60.9-35.1-174.3-66.40000113.6L210 F211 N244L210-V246 HydrophobicContact CB-CG2 4.3Å; F211-V246 HydrophobicContact CB-CB 4.31Å; F211-V246 HydrophobicContact CB-CG2 3.91Å; F211-V246 WeakPolarHBondContact CD2-O 3.24Å; N244-V246 PolarHBondContact O-N 3.48Å; N244-V246 VanDerWaalsContact OD1-CG1 3.28Å; N244-V246 WeakPolarHBondContact OD1-CG1 3.36Å; N244-V246 WeakPolarHBondContact OD1-CG2 3.45Å; N244-V246 PolarHBondContact OD1-N 2.71Å
247G90.9Very high93Very high0 Ų046.2 Ų46.20%026%0.264CS..THydrogen-bonded Turntrans-84.6-8.5178.400000114.6S214 L245 N249 Y250 I251S214-G247 WeakPolarHBondContact CB-O 3.39Å; L245-G247 VanDerWaalsContact C-N 3.3Å; L245-G247 PolarHBondContact O-N 3.49Å; G247-N249 VanDerWaalsContact C-N 3.28Å; G247-N249 PolarHBondContact O-N 3.21Å; G247-N249 VanDerWaalsContact O-N 3.16Å; G247-Y250 PolarHBondContact O-N 2.7Å; G247-I251 PolarHBondContact O-N 3.33Å
248L93.6Very high92.6Very high0 Ų043.2 Ų43.20%025%0.254CS..Hα-helixtrans-60.2-35.4-168.1-174.867.3000113.1L236 L245 Y250 I251 I252 V270 L280 I283L236-L248 HydrophobicContact CD1-CD1 3.69Å; L245-L248 HydrophobicContact CB-CB 4.35Å; L245-L248 HydrophobicContact CB-CD2 4.48Å; L245-L248 WeakPolarHBondContact O-CB 3.4Å; L245-L248 PolarHBondContact O-N 2.87Å; L245-L248 VanDerWaalsContact O-N 3.11Å; L248-Y250 PolarHBondContact O-N 3.36Å; L248-I251 HydrophobicContact CD1-CB 4.45Å; L248-I251 HydrophobicContact CD1-CG2 4.4Å; L248-I251 WeakPolarHBondContact O-CB 3.39Å; L248-I251 PolarHBondContact O-N 2.93Å; L248-I252 HydrophobicContact CD1-CD1 4.18Å; L248-I252 HydrophobicContact CD1-CG1 4.14Å; L248-I252 HydrophobicContact CG-CG1 4.05Å; L248-I252 WeakPolarHBondContact O-CG1 3.35Å; L248-I252 PolarHBondContact O-N 3.3Å; L248-V270 HydrophobicContact CD2-CG1 4.31Å; L248-L280 HydrophobicContact CD2-CD2 3.2Å; L248-L280 HydrophobicContact CD2-CG 4.3Å; L248-I283 HydrophobicContact CD2-CD1 4.17Å; L248-I283 HydrophobicContact CG-CD1 4.41Å
249N92.1Very high92.3Very high79 Ų7941.6 Ų41.642%0.42225%0.254SS..Hα-helixtrans-54.7-41177.6-75-57.4000112G247 I252 E253 I283G247-N249 VanDerWaalsContact C-N 3.28Å; G247-N249 PolarHBondContact O-N 3.21Å; G247-N249 VanDerWaalsContact O-N 3.16Å; N249-I252 PolarHBondContact O-N 3.15Å; N249-E253 WeakPolarHBondContact O-CG 3.32Å; N249-E253 PolarHBondContact O-N 3.5Å; N249-I283 WeakPolarHBondContact OD1-CD1 3.25Å; N249-I283 WeakPolarHBondContact OD1-CG1 3.49Å
250Y95Very high92Very high24 Ų2445 Ų459%0.09427%0.267CS..Hα-helixtrans-74.6-37-178.8-56.7-58.3000112.6K180 F211 L215 L218 G247 L248 I252 E253 Y254K180-Y250 WeakPolarHBondContact CE-OH 3.39Å; K180-Y250 PolarHBondContact NZ-OH 3.44Å; F211-Y250 HydrophobicContact CD1-CE2 4.14Å; F211-Y250 AromaticContact CD2-CE2 3.73Å; F211-Y250 HydrophobicContact CD2-CE2 3.73Å; F211-Y250 AromaticContact CE1-CE2 3.84Å; F211-Y250 HydrophobicContact CE1-CE2 3.84Å; F211-Y250 AromaticContact CE2-CE2 3.44Å; F211-Y250 HydrophobicContact CE2-CE2 3.44Å; F211-Y250 VanDerWaalsContact CE2-CE2 3.44Å; F211-Y250 AromaticContact CE2-CZ 3.86Å; F211-Y250 WeakPolarHBondContact CE2-OH 3.19Å; F211-Y250 HydrophobicContact CG-CE2 4.07Å; F211-Y250 AromaticContact CZ-CE2 3.52Å; F211-Y250 HydrophobicContact CZ-CE2 3.52Å; F211-Y250 AromaticContact CZ-CZ 3.67Å; F211-Y250 WeakPolarHBondContact CZ-OH 3.49Å; L215-Y250 HydrophobicContact CB-CD2 3.87Å; L215-Y250 HydrophobicContact CB-CE2 3.8Å; L215-Y250 HydrophobicContact CB-CG 4.31Å; L215-Y250 HydrophobicContact CD1-CD1 3.94Å; L215-Y250 HydrophobicContact CD1-CE1 3.66Å; L215-Y250 HydrophobicContact CD1-CE2 4.26Å; L215-Y250 HydrophobicContact CD1-CG 4.38Å; L215-Y250 HydrophobicContact CG-CE2 4.42Å; L218-Y250 HydrophobicContact CD2-CD1 3.74Å; L218-Y250 HydrophobicContact CD2-CG 4.26Å; G247-Y250 PolarHBondContact O-N 2.7Å; L248-Y250 PolarHBondContact O-N 3.36Å; Y250-I252 VanDerWaalsContact C-N 3.27Å; Y250-I252 PolarHBondContact O-N 3.03Å; Y250-E253 PolarHBondContact O-N 3.3Å; Y250-Y254 PolarHBondContact O-N 3.22Å
251I96Very high91.9Very high0 Ų044.3 Ų44.30%027%0.27CS..Hα-helixtrans-57.6-43.6171-66.9171.4000110.4I232 L235 L236 G247 L248 Y254 F255I232-I251 HydrophobicContact CG2-CG2 3.86Å; L235-I251 HydrophobicContact CB-CD1 3.96Å; L235-I251 HydrophobicContact CB-CG1 4.49Å; L236-I251 HydrophobicContact CB-CD1 4.32Å; L236-I251 HydrophobicContact CB-CG2 4.24Å; L236-I251 HydrophobicContact CD1-CG2 4.28Å; G247-I251 PolarHBondContact O-N 3.33Å; L248-I251 HydrophobicContact CD1-CB 4.45Å; L248-I251 HydrophobicContact CD1-CG2 4.4Å; L248-I251 WeakPolarHBondContact O-CB 3.39Å; L248-I251 PolarHBondContact O-N 2.93Å; I251-Y254 WeakPolarHBondContact O-CB 3.46Å; I251-Y254 PolarHBondContact O-N 3.38Å; I251-F255 HydrophobicContact CG2-CD2 4.06Å; I251-F255 HydrophobicContact CG2-CE2 3.5Å; I251-F255 VanDerWaalsContact CG2-CE2 3.5Å; I251-F255 HydrophobicContact CG2-CZ 4.34Å; I251-F255 VanDerWaalsContact O-CD2 3.25Å; I251-F255 WeakPolarHBondContact O-CD2 3.45Å; I251-F255 PolarHBondContact O-N 3.45Å
252I94.6Very high91.7Very high2 Ų242.6 Ų42.61%0.0125%0.248CC..Hα-helixtrans-73-36178.9-60.9-47.1000112.1L248 N249 Y250 Y254 F255 K256 A263 E266 V267 I283 L287L248-I252 HydrophobicContact CD1-CD1 4.18Å; L248-I252 HydrophobicContact CD1-CG1 4.14Å; L248-I252 HydrophobicContact CG-CG1 4.05Å; L248-I252 WeakPolarHBondContact O-CG1 3.35Å; L248-I252 PolarHBondContact O-N 3.3Å; N249-I252 PolarHBondContact O-N 3.15Å; Y250-I252 VanDerWaalsContact C-N 3.27Å; Y250-I252 PolarHBondContact O-N 3.03Å; I252-Y254 VanDerWaalsContact C-N 3.26Å; I252-Y254 PolarHBondContact O-N 3.03Å; I252-F255 HydrophobicContact CD1-CD2 3.94Å; I252-F255 HydrophobicContact CD1-CE2 4.47Å; I252-F255 PolarHBondContact O-N 3.19Å; I252-K256 HydrophobicContact CG2-CD 4.15Å; I252-K256 HydrophobicContact CG2-CG 4.28Å; I252-K256 WeakPolarHBondContact O-CB 3.31Å; I252-K256 VanDerWaalsContact O-CG 3.26Å; I252-K256 WeakPolarHBondContact O-CG 3.4Å; I252-K256 PolarHBondContact O-N 3.09Å; I252-A263 HydrophobicContact CG2-CB 4.34Å; I252-E266 HydrophobicContact CD1-CB 4.43Å; I252-V267 HydrophobicContact CB-CG2 4.49Å; I252-V267 HydrophobicContact CD1-CG2 3.3Å; I252-V267 HydrophobicContact CG1-CG2 3.56Å; I252-V267 HydrophobicContact CG2-CG2 4.08Å; I252-I283 HydrophobicContact CB-CG2 4.3Å; I252-I283 HydrophobicContact CG1-CG2 4.15Å; I252-I283 HydrophobicContact CG2-CG2 3.79Å; I252-L287 HydrophobicContact CG2-CD1 3.98Å; I252-L287 HydrophobicContact CG2-CD2 4.15Å; I252-L287 HydrophobicContact CG2-CG 4.41Å
253E93Very high91.8Very high87 Ų8739 Ų3941%0.40723%0.227SC..Hα-helixtrans-59.4-37.5171.8-72.3-55.3142.400112L218 N249 Y250 K256 G257L218-E253 HydrophobicContact CD1-CB 4.31Å; L218-E253 HydrophobicContact CD2-CB 3.95Å; N249-E253 WeakPolarHBondContact O-CG 3.32Å; N249-E253 PolarHBondContact O-N 3.5Å; Y250-E253 PolarHBondContact O-N 3.3Å; E253-K256 PolarHBondContact O-N 2.96Å; E253-K256 IonicContact OE1-NZ 3.67Å; E253-K256 PolarHBondContact OE1-NZ 3.02Å; E253-K256 IonicContact OE2-NZ 3.56Å; E253-K256 PolarHBondContact OE2-NZ 2.62Å; E253-G257 PolarHBondContact O-N 3.23Å; E253-G257 VanDerWaalsContact O-N 3.08Å
254Y95Very high92Very high6 Ų636.1 Ų36.12%0.02420%0.201CC..Hα-helixtrans-59.6-53.4171.2170.6-97.7000111.9F221 V228 D229 I232 Y250 I251 I252 K256 G257 I258F221-Y254 HydrophobicContact CB-CD2 4.29Å; F221-Y254 HydrophobicContact CB-CE2 4.45Å; F221-Y254 AromaticContact CD1-CD2 3.86Å; F221-Y254 HydrophobicContact CD1-CD2 3.86Å; F221-Y254 HydrophobicContact CD1-CE2 4.31Å; F221-Y254 HydrophobicContact CD2-CD2 4.19Å; F221-Y254 AromaticContact CD2-CE2 3.8Å; F221-Y254 HydrophobicContact CD2-CE2 3.8Å; F221-Y254 HydrophobicContact CE1-CD2 4.21Å; F221-Y254 HydrophobicContact CE2-CE2 4.07Å; F221-Y254 AromaticContact CG-CD2 3.84Å; F221-Y254 HydrophobicContact CG-CD2 3.84Å; F221-Y254 AromaticContact CG-CE2 3.92Å; F221-Y254 HydrophobicContact CG-CE2 3.92Å; F221-Y254 HydrophobicContact CZ-CE2 4.44Å; V228-Y254 HydrophobicContact CG2-CD2 3.84Å; V228-Y254 HydrophobicContact CG2-CE2 3.42Å; V228-Y254 VanDerWaalsContact CG2-CE2 3.42Å; D229-Y254 WeakPolarHBondContact CA-OH 3.43Å; D229-Y254 PolarHBondContact N-OH 2.87Å; D229-Y254 WeakPolarHBondContact OD1-CE1 3.41Å; D229-Y254 PolarHBondContact OD1-OH 2.86Å; D229-Y254 PolarHBondContact OD2-OH 3.3Å; I232-Y254 HydrophobicContact CB-CD1 4.07Å; I232-Y254 HydrophobicContact CB-CE1 4.18Å; I232-Y254 HydrophobicContact CD1-CD1 4.45Å; I232-Y254 HydrophobicContact CD1-CG 4.16Å; I232-Y254 HydrophobicContact CG1-CD1 3.8Å; I232-Y254 HydrophobicContact CG1-CD2 4.22Å; I232-Y254 HydrophobicContact CG1-CE1 4.08Å; I232-Y254 HydrophobicContact CG1-CG 3.84Å; I232-Y254 HydrophobicContact CG2-CD1 3.68Å; I232-Y254 HydrophobicContact CG2-CE1 4.12Å; I232-Y254 HydrophobicContact CG2-CG 4.38Å; Y250-Y254 PolarHBondContact O-N 3.22Å; I251-Y254 WeakPolarHBondContact O-CB 3.46Å; I251-Y254 PolarHBondContact O-N 3.38Å; I252-Y254 VanDerWaalsContact C-N 3.26Å; I252-Y254 PolarHBondContact O-N 3.03Å; Y254-K256 VanDerWaalsContact C-N 3.27Å; Y254-K256 PolarHBondContact O-N 2.89Å; Y254-G257 WeakPolarHBondContact O-CA 3.46Å; Y254-G257 PolarHBondContact O-N 3.41Å; Y254-I258 HydrophobicContact CD1-CD1 4.32Å; Y254-I258 HydrophobicContact CE1-CD1 3.62Å; Y254-I258 HydrophobicContact CE2-CD1 4.34Å; Y254-I258 PolarHBondContact O-N 3.33Å
255F93.9Very high92.3Very high0 Ų039 Ų390%021%0.213CC..Hα-helixtrans-61.6-35.6179.5-66.4-52.3000112.7I232 Q233 L236 I251 I252 G257 I258 S259 R262 A263 E266I232-F255 HydrophobicContact CG2-CE1 4.15Å; I232-F255 HydrophobicContact CG2-CE2 4.13Å; I232-F255 HydrophobicContact CG2-CZ 3.69Å; Q233-F255 VanDerWaalsContact NE2-CZ 3.34Å; L236-F255 HydrophobicContact CD2-CE2 4.2Å; L236-F255 HydrophobicContact CD2-CZ 4.43Å; I251-F255 HydrophobicContact CG2-CD2 4.06Å; I251-F255 HydrophobicContact CG2-CE2 3.5Å; I251-F255 VanDerWaalsContact CG2-CE2 3.5Å; I251-F255 HydrophobicContact CG2-CZ 4.34Å; I251-F255 VanDerWaalsContact O-CD2 3.25Å; I251-F255 WeakPolarHBondContact O-CD2 3.45Å; I251-F255 PolarHBondContact O-N 3.45Å; I252-F255 HydrophobicContact CD1-CD2 3.94Å; I252-F255 HydrophobicContact CD1-CE2 4.47Å; I252-F255 PolarHBondContact O-N 3.19Å; F255-G257 VanDerWaalsContact C-N 3.27Å; F255-G257 PolarHBondContact O-N 3.03Å; F255-I258 WeakPolarHBondContact O-CB 3.46Å; F255-I258 PolarHBondContact O-N 3.41Å; F255-S259 PolarHBondContact O-N 2.9Å; F255-R262 HydrophobicContact CD1-CG 4Å; F255-R262 HydrophobicContact CG-CG 4.49Å; F255-A263 HydrophobicContact CB-CB 3.81Å; F255-E266 HydrophobicContact CD2-CB 4.06Å; F255-E266 HydrophobicContact CD2-CG 3.85Å; F255-E266 HydrophobicContact CE1-CG 4.38Å; F255-E266 HydrophobicContact CE2-CB 4.02Å; F255-E266 HydrophobicContact CE2-CG 3.67Å; F255-E266 HydrophobicContact CG-CG 4.28Å; F255-E266 HydrophobicContact CZ-CG 3.96Å
256K90.5Very high92.4Very high45 Ų4538.2 Ų38.220%0.19621%0.209CC..Hα-helixtrans-61.4-35.6173.8-75.6169.968.2-145.90112.3I252 E253 Y254 I258 Y260 A263 L287I252-K256 HydrophobicContact CG2-CD 4.15Å; I252-K256 HydrophobicContact CG2-CG 4.28Å; I252-K256 WeakPolarHBondContact O-CB 3.31Å; I252-K256 VanDerWaalsContact O-CG 3.26Å; I252-K256 WeakPolarHBondContact O-CG 3.4Å; I252-K256 PolarHBondContact O-N 3.09Å; E253-K256 PolarHBondContact O-N 2.96Å; E253-K256 IonicContact OE1-NZ 3.67Å; E253-K256 PolarHBondContact OE1-NZ 3.02Å; E253-K256 IonicContact OE2-NZ 3.56Å; E253-K256 PolarHBondContact OE2-NZ 2.62Å; Y254-K256 VanDerWaalsContact C-N 3.27Å; Y254-K256 PolarHBondContact O-N 2.89Å; K256-I258 PolarHBondContact O-N 3.08Å; K256-Y260 HydrophobicContact CG-CD1 4.44Å; K256-Y260 HydrophobicContact CG-CE1 4.45Å; K256-A263 HydrophobicContact CG-CB 3.86Å; K256-L287 HydrophobicContact CD-CD2 3.56Å; K256-L287 HydrophobicContact CG-CD2 3.37Å
257G86.4Confident92.7Very high57 Ų5734.8 Ų34.859%0.58819%0.188SC*.Hα-helixtrans-61.8-25.6173.800000113.3E253 Y254 F255E253-G257 PolarHBondContact O-N 3.23Å; E253-G257 VanDerWaalsContact O-N 3.08Å; Y254-G257 WeakPolarHBondContact O-CA 3.46Å; Y254-G257 PolarHBondContact O-N 3.41Å; F255-G257 VanDerWaalsContact C-N 3.27Å; F255-G257 PolarHBondContact O-N 3.03Å
258I87.9Confident93Very high81 Ų8138 Ų3842%0.41520%0.203SC..Hα-helixtrans-90-60.6176.6-57.4176.2000110.6Y254 F255 K256Y254-I258 HydrophobicContact CD1-CD1 4.32Å; Y254-I258 HydrophobicContact CE1-CD1 3.62Å; Y254-I258 HydrophobicContact CE2-CD1 4.34Å; Y254-I258 PolarHBondContact O-N 3.33Å; F255-I258 WeakPolarHBondContact O-CB 3.46Å; F255-I258 PolarHBondContact O-N 3.41Å; K256-I258 PolarHBondContact O-N 3.08Å
259S90.1Very high93Very high52 Ų5243 Ų4336%0.36422%0.222SC..  trans-162.7148.5171.978.50000112.4F255 G261 R262 A263F255-S259 PolarHBondContact O-N 2.9Å; S259-G261 PolarHBondContact O-N 3.12Å; S259-R262 PolarHBondContact O-N 3.2Å; S259-R262 WeakPolarHBondContact OG-CB 3.2Å; S259-R262 PolarHBondContact OG-N 3Å; S259-R262 VanDerWaalsContact OG-N 3.16Å; S259-A263 PolarHBondContact O-N 3.22Å
260Y89.7Confident93.2Very high71 Ų7139.2 Ų39.228%0.27820%0.202SC..Hα-helixtrans-61.3-31.1172.6-70.1-68.5000113.1K256 I264 L287 W290K256-Y260 HydrophobicContact CG-CD1 4.44Å; K256-Y260 HydrophobicContact CG-CE1 4.45Å; Y260-I264 WeakPolarHBondContact O-CB 3.46Å; Y260-I264 WeakPolarHBondContact O-CD1 3.47Å; Y260-I264 WeakPolarHBondContact O-CG1 3.2Å; Y260-I264 PolarHBondContact O-N 2.92Å; Y260-L287 HydrophobicContact CD1-CD2 4.3Å; Y260-W290 HydrophobicContact CD1-CB 3.92Å; Y260-W290 HydrophobicContact CE1-CB 3.32Å; Y260-W290 AromaticContact CE1-CG 4Å; Y260-W290 HydrophobicContact CE1-CG 4Å; Y260-W290 HydrophobicContact CE2-CB 4.43Å
261G91.3Very high93.2Very high25 Ų2540.6 Ų40.626%0.25821%0.207SC..Hα-helixtrans-63.3-53.1178.700000111.7S259 A263 I264 E265S259-G261 PolarHBondContact O-N 3.12Å; G261-A263 VanDerWaalsContact C-N 3.31Å; G261-A263 PolarHBondContact O-N 3.16Å; G261-I264 WeakPolarHBondContact O-CB 3.43Å; G261-I264 PolarHBondContact O-N 2.86Å; G261-E265 WeakPolarHBondContact O-CG 3.49Å; G261-E265 PolarHBondContact O-N 3.09Å
262R91.4Very high93.1Very high63 Ų6348 Ų4824%0.23824%0.241CC..Hα-helixtrans-56.9-45.1176.8-172174.7-176.9-166.2-3.7111.3D229 F255 S259 I264 E265 E266D229-R262 IonicContact OD1-CZ 3.5Å; D229-R262 IonicContact OD1-NH1 3.71Å; D229-R262 PolarHBondContact OD1-NH1 2.93Å; D229-R262 IonicContact OD1-NH2 3.82Å; D229-R262 PolarHBondContact OD1-NH2 3.43Å; D229-R262 IonicContact OD2-NH1 2.73Å; D229-R262 PolarHBondContact OD2-NH1 2.9Å; D229-R262 IonicContact OD2-NH2 3.66Å; F255-R262 HydrophobicContact CD1-CG 4Å; F255-R262 HydrophobicContact CG-CG 4.49Å; S259-R262 PolarHBondContact O-N 3.2Å; S259-R262 WeakPolarHBondContact OG-CB 3.2Å; S259-R262 PolarHBondContact OG-N 3Å; S259-R262 VanDerWaalsContact OG-N 3.16Å; R262-I264 VanDerWaalsContact C-N 3.32Å; R262-I264 PolarHBondContact O-N 3.3Å; R262-E265 PolarHBondContact O-N 2.9Å; R262-E266 VanDerWaalsContact O-CG 3.28Å; R262-E266 WeakPolarHBondContact O-CG 3.48Å; R262-E266 PolarHBondContact O-N 3.42Å; R262-E266 VanDerWaalsContact O-N 3.08Å
263A95.4Very high93.2Very high0 Ų052.2 Ų52.20%026%0.263CS..Hα-helixtrans-60.8-39.5177.300000112.9I252 F255 K256 S259 G261 V267 L287I252-A263 HydrophobicContact CG2-CB 4.34Å; F255-A263 HydrophobicContact CB-CB 3.81Å; K256-A263 HydrophobicContact CG-CB 3.86Å; S259-A263 PolarHBondContact O-N 3.22Å; G261-A263 VanDerWaalsContact C-N 3.31Å; G261-A263 PolarHBondContact O-N 3.16Å; A263-V267 VanDerWaalsContact O-CG2 3.27Å; A263-V267 WeakPolarHBondContact O-CG2 3.36Å; A263-V267 PolarHBondContact O-N 3.32Å; A263-V267 VanDerWaalsContact O-N 3.12Å; A263-L287 HydrophobicContact CB-CD1 4.03Å; A263-L287 HydrophobicContact CB-CD2 3.67Å; A263-L287 WeakPolarHBondContact O-CD1 3.44Å
264I95.6Very high93.2Very high5 Ų550 Ų503%0.02625%0.252CS..Hα-helixtrans-65.5-47.6177.8-73.5164.9000110.8Y260 G261 R262 E266 V267 Q268 L284 L287 Y288 K291 W305Y260-I264 WeakPolarHBondContact O-CB 3.46Å; Y260-I264 WeakPolarHBondContact O-CD1 3.47Å; Y260-I264 WeakPolarHBondContact O-CG1 3.2Å; Y260-I264 PolarHBondContact O-N 2.92Å; G261-I264 WeakPolarHBondContact O-CB 3.43Å; G261-I264 PolarHBondContact O-N 2.86Å; R262-I264 VanDerWaalsContact C-N 3.32Å; R262-I264 PolarHBondContact O-N 3.3Å; I264-E266 PolarHBondContact O-N 3.47Å; I264-V267 PolarHBondContact O-N 3.04Å; I264-Q268 HydrophobicContact CG2-CG 4.23Å; I264-Q268 WeakPolarHBondContact O-CB 3.49Å; I264-Q268 VanDerWaalsContact O-CG 3.29Å; I264-Q268 WeakPolarHBondContact O-CG 3.42Å; I264-Q268 PolarHBondContact O-N 3.11Å; I264-L284 HydrophobicContact CG2-CD1 4.46Å; I264-L287 HydrophobicContact CD1-CB 4.41Å; I264-L287 HydrophobicContact CG1-CB 3.71Å; I264-L287 HydrophobicContact CG1-CD1 4.21Å; I264-Y288 HydrophobicContact CD1-CD2 4.22Å; I264-Y288 HydrophobicContact CD1-CE2 4.34Å; I264-Y288 HydrophobicContact CG1-CD2 4.23Å; I264-Y288 HydrophobicContact CG1-CE2 4.23Å; I264-Y288 HydrophobicContact CG2-CD2 4.48Å; I264-Y288 HydrophobicContact CG2-CE2 3.67Å; I264-K291 HydrophobicContact CD1-CB 4.14Å; I264-K291 HydrophobicContact CD1-CG 4.41Å; I264-W305 HydrophobicContact CD1-CH2 4.11Å; I264-W305 HydrophobicContact CD1-CZ3 3.92Å
265E94.8Very high93Very high121 Ų12154 Ų5457%0.56528%0.278SS*.Hα-helixtrans-58.1-46.7179.6-71.2168.1-168.100111.7G261 R262 Q268 R269G261-E265 WeakPolarHBondContact O-CG 3.49Å; G261-E265 PolarHBondContact O-N 3.09Å; R262-E265 PolarHBondContact O-N 2.9Å; E265-Q268 PolarHBondContact O-N 3.41Å; E265-R269 PolarHBondContact O-N 3.46Å
266E94.9Very high92.8Very high12 Ų1259.6 Ų59.66%0.05632%0.318CS..Hα-helixtrans-62.3-45.7178.3-67-65.5156.700111.7L236 I252 F255 R262 I264 Q268 R269 V270L236-E266 WeakPolarHBondContact CD2-OE2 3.39Å; I252-E266 HydrophobicContact CD1-CB 4.43Å; F255-E266 HydrophobicContact CD2-CB 4.06Å; F255-E266 HydrophobicContact CD2-CG 3.85Å; F255-E266 HydrophobicContact CE1-CG 4.38Å; F255-E266 HydrophobicContact CE2-CB 4.02Å; F255-E266 HydrophobicContact CE2-CG 3.67Å; F255-E266 HydrophobicContact CG-CG 4.28Å; F255-E266 HydrophobicContact CZ-CG 3.96Å; R262-E266 VanDerWaalsContact O-CG 3.28Å; R262-E266 WeakPolarHBondContact O-CG 3.48Å; R262-E266 PolarHBondContact O-N 3.42Å; R262-E266 VanDerWaalsContact O-N 3.08Å; I264-E266 PolarHBondContact O-N 3.47Å; E266-Q268 PolarHBondContact O-N 2.88Å; E266-R269 PolarHBondContact O-N 3.37Å; E266-R269 IonicContact OE1-CZ 3.94Å; E266-R269 IonicContact OE1-NH1 3.82Å; E266-R269 PolarHBondContact OE1-NH1 3.26Å; E266-R269 IonicContact OE1-NH2 3.66Å; E266-R269 PolarHBondContact OE1-NH2 3.28Å; E266-R269 IonicContact OE2-CZ 3.49Å; E266-R269 IonicContact OE2-NH1 3.04Å; E266-R269 PolarHBondContact OE2-NH1 3.04Å; E266-R269 IonicContact OE2-NH2 3.89Å; E266-R269 PolarHBondContact OE2-NH2 2.95Å; E266-R269 VanDerWaalsContact OE2-NH2 3.13Å; E266-V270 VanDerWaalsContact O-CG2 3.27Å; E266-V270 WeakPolarHBondContact O-CG2 3.37Å; E266-V270 PolarHBondContact O-N 3.04Å; E266-V270 VanDerWaalsContact O-N 3.11Å
267V95.4Very high92.8Very high0 Ų058.8 Ų58.80%032%0.317CS..Hα-helixtrans-68.1-36.7179.3176.40000112I252 A263 I264 V270 R271 L280 I283 L284 L287I252-V267 HydrophobicContact CB-CG2 4.49Å; I252-V267 HydrophobicContact CD1-CG2 3.3Å; I252-V267 HydrophobicContact CG1-CG2 3.56Å; I252-V267 HydrophobicContact CG2-CG2 4.08Å; A263-V267 VanDerWaalsContact O-CG2 3.27Å; A263-V267 WeakPolarHBondContact O-CG2 3.36Å; A263-V267 PolarHBondContact O-N 3.32Å; A263-V267 VanDerWaalsContact O-N 3.12Å; I264-V267 PolarHBondContact O-N 3.04Å; V267-V270 PolarHBondContact O-N 3.47Å; V267-R271 WeakPolarHBondContact O-CB 3.45Å; V267-R271 PolarHBondContact O-N 2.8Å; V267-L280 HydrophobicContact CG1-CD2 4.17Å; V267-I283 HydrophobicContact CG1-CG2 4.21Å; V267-I283 HydrophobicContact CG2-CG2 3.76Å; V267-L284 HydrophobicContact CB-CD1 4.19Å; V267-L284 HydrophobicContact CG1-CB 3.85Å; V267-L284 HydrophobicContact CG1-CD1 3.88Å; V267-L284 HydrophobicContact CG1-CG 4.41Å; V267-L287 HydrophobicContact CB-CD1 4.13Å; V267-L287 HydrophobicContact CG2-CD1 3.67Å
268Q95.3Very high92.8Very high69 Ų6957.7 Ų57.732%0.32230%0.301SS..Hα-helixtrans-62-47175.8-76.6177.9-48.100111.1I264 E265 E266 V270 R271 E272 L284 Y288I264-Q268 HydrophobicContact CG2-CG 4.23Å; I264-Q268 WeakPolarHBondContact O-CB 3.49Å; I264-Q268 VanDerWaalsContact O-CG 3.29Å; I264-Q268 WeakPolarHBondContact O-CG 3.42Å; I264-Q268 PolarHBondContact O-N 3.11Å; E265-Q268 PolarHBondContact O-N 3.41Å; E266-Q268 PolarHBondContact O-N 2.88Å; Q268-V270 VanDerWaalsContact C-N 3.31Å; Q268-V270 PolarHBondContact O-N 3.39Å; Q268-R271 PolarHBondContact O-N 3.02Å; Q268-E272 WeakPolarHBondContact O-CG 3.16Å; Q268-E272 PolarHBondContact O-N 2.93Å; Q268-L284 HydrophobicContact CG-CD1 3.93Å; Q268-Y288 PolarHBondContact NE2-OH 3.44Å
269R95.2Very high92.8Very high104 Ų10456.6 Ų56.639%0.39230%0.298SS..Hα-helixtrans-57-43.9175.9-165.4-166.2-47.61409.8112.2E265 E266 R271 E272E265-R269 PolarHBondContact O-N 3.46Å; E266-R269 PolarHBondContact O-N 3.37Å; E266-R269 IonicContact OE1-CZ 3.94Å; E266-R269 IonicContact OE1-NH1 3.82Å; E266-R269 PolarHBondContact OE1-NH1 3.26Å; E266-R269 IonicContact OE1-NH2 3.66Å; E266-R269 PolarHBondContact OE1-NH2 3.28Å; E266-R269 IonicContact OE2-CZ 3.49Å; E266-R269 IonicContact OE2-NH1 3.04Å; E266-R269 PolarHBondContact OE2-NH1 3.04Å; E266-R269 IonicContact OE2-NH2 3.89Å; E266-R269 PolarHBondContact OE2-NH2 2.95Å; E266-R269 VanDerWaalsContact OE2-NH2 3.13Å; R269-R271 VanDerWaalsContact C-N 3.35Å; R269-E272 PolarHBondContact O-N 3.21Å
270V95.6Very high92.9Very high0 Ų054.1 Ų54.10%028%0.281CS..Hα-helixtrans-68-36.5177.4-177.40000111.1L236 I240 L245 L248 E266 V267 Q268 I273 F274 L280L236-V270 HydrophobicContact CD1-CG2 3.8Å; I240-V270 HydrophobicContact CD1-CG2 3.96Å; I240-V270 HydrophobicContact CG1-CG1 4.45Å; I240-V270 HydrophobicContact CG1-CG2 4.2Å; L245-V270 HydrophobicContact CD2-CG1 4.1Å; L248-V270 HydrophobicContact CD2-CG1 4.31Å; E266-V270 VanDerWaalsContact O-CG2 3.27Å; E266-V270 WeakPolarHBondContact O-CG2 3.37Å; E266-V270 PolarHBondContact O-N 3.04Å; E266-V270 VanDerWaalsContact O-N 3.11Å; V267-V270 PolarHBondContact O-N 3.47Å; Q268-V270 VanDerWaalsContact C-N 3.31Å; Q268-V270 PolarHBondContact O-N 3.39Å; V270-I273 PolarHBondContact O-N 2.98Å; V270-F274 HydrophobicContact CG1-CD2 3.86Å; V270-F274 HydrophobicContact CG1-CE2 4.33Å; V270-F274 WeakPolarHBondContact O-CD2 3.41Å; V270-F274 PolarHBondContact O-N 3.2Å; V270-L280 HydrophobicContact CB-CD1 4.47Å; V270-L280 HydrophobicContact CB-CD2 4.22Å; V270-L280 HydrophobicContact CG1-CD1 3.8Å; V270-L280 HydrophobicContact CG1-CD2 3.85Å; V270-L280 HydrophobicContact CG1-CG 4.49Å
271R94.9Very high93Very high53 Ų5350.9 Ų50.920%0.227%0.268CS..Hα-helixtrans-69-31178.7-171.7178.7179.6-171.93112.8V267 Q268 R269 I273 F274 P275 L280 L284 E315V267-R271 WeakPolarHBondContact O-CB 3.45Å; V267-R271 PolarHBondContact O-N 2.8Å; Q268-R271 PolarHBondContact O-N 3.02Å; R269-R271 VanDerWaalsContact C-N 3.35Å; R271-I273 PolarHBondContact O-N 3.03Å; R271-F274 CarbonylContact O-C 3.19Å; R271-F274 PolarHBondContact O-N 3.16Å; R271-P275 WeakPolarHBondContact O-CA 3.39Å; R271-L280 HydrophobicContact CB-CD1 4.3Å; R271-L284 VanDerWaalsContact NH1-CD2 3.35Å; R271-E315 IonicContact NH2-OE1 4Å; R271-E315 IonicContact NH2-OE2 3Å; R271-E315 PolarHBondContact NH2-OE2 3.1Å
272E95.2Very high93.1Very high155 Ų15552.9 Ų52.972%0.72427%0.27SS*.Hα-helixtrans-59.8-34.5172.4-72.2168.9-175.500111.8Q268 R269Q268-E272 WeakPolarHBondContact O-CG 3.16Å; Q268-E272 PolarHBondContact O-N 2.93Å; R269-E272 PolarHBondContact O-N 3.21Å
273I95.4Very high93.1Very high90 Ų9050.6 Ų50.646%0.46226%0.262SS..Hα-helixtrans-80.4-38.3177.3-54.6171.4000111I240 V270 R271 P275I240-I273 HydrophobicContact CG2-CD1 3.56Å; V270-I273 PolarHBondContact O-N 2.98Å; R271-I273 PolarHBondContact O-N 3.03Å; I273-P275 VanDerWaalsContact C-CD 3.41Å; I273-P275 VanDerWaalsContact O-CD 3.31Å; I273-P275 WeakPolarHBondContact O-CD 3.46Å
274F93.8Very high93.1Very high41 Ų4150.9 Ų50.918%0.1826%0.264CS..  trans-121.765.7-177-54-74.1000112.4I240 A243 L245 V270 R271 S276 S277 L280I240-F274 HydrophobicContact CG2-CE2 4.24Å; A243-F274 HydrophobicContact CB-CE1 3.75Å; A243-F274 HydrophobicContact CB-CZ 4.01Å; L245-F274 HydrophobicContact CD1-CB 4.37Å; L245-F274 HydrophobicContact CD1-CD2 4.01Å; L245-F274 HydrophobicContact CD1-CG 4.19Å; L245-F274 HydrophobicContact CD2-CD2 4.24Å; L245-F274 HydrophobicContact CD2-CE2 4.07Å; V270-F274 HydrophobicContact CG1-CD2 3.86Å; V270-F274 HydrophobicContact CG1-CE2 4.33Å; V270-F274 WeakPolarHBondContact O-CD2 3.41Å; V270-F274 PolarHBondContact O-N 3.2Å; R271-F274 CarbonylContact O-C 3.19Å; R271-F274 PolarHBondContact O-N 3.16Å; F274-S276 VanDerWaalsContact C-N 3.26Å; F274-S276 PolarHBondContact O-N 2.79Å; F274-S277 WeakPolarHBondContact O-CB 2.92Å; F274-S277 PolarHBondContact O-N 2.94Å; F274-S277 VanDerWaalsContact O-N 3.16Å; F274-L280 HydrophobicContact CB-CD1 3.77Å
275P91.2Very high93.1Very high90 Ų9050.7 Ų50.758%0.58426%0.263SS*.THydrogen-bonded Turntrans-65.9-27.1-169.724.8-35000113.8R271 I273 S277R271-P275 WeakPolarHBondContact O-CA 3.39Å; I273-P275 VanDerWaalsContact C-CD 3.41Å; I273-P275 VanDerWaalsContact O-CD 3.31Å; I273-P275 WeakPolarHBondContact O-CD 3.46Å; P275-S277 VanDerWaalsContact C-N 3.33Å
276S89.4Confident93.1Very high118 Ų11847.1 Ų47.183%0.82525%0.248SC*.THydrogen-bonded Turntrans-84.4-0.6-179.856.30000114.3F274 S278F274-S276 VanDerWaalsContact C-N 3.26Å; F274-S276 PolarHBondContact O-N 2.79Å; S276-S278 PolarHBondContact O-N 2.72Å; S276-S278 VanDerWaalsContact O-N 3.14Å
277S89.3Confident93.1Very high27 Ų2746.7 Ų46.719%0.18925%0.246CC..  trans-74.4107.6-177.21800000111.9F274 P275 T279 L280 L281F274-S277 WeakPolarHBondContact O-CB 2.92Å; F274-S277 PolarHBondContact O-N 2.94Å; F274-S277 VanDerWaalsContact O-N 3.16Å; P275-S277 VanDerWaalsContact C-N 3.33Å; S277-T279 PolarHBondContact O-N 3.43Å; S277-L280 PolarHBondContact O-N 3.37Å; S277-L280 VanDerWaalsContact O-N 3.13Å; S277-L280 PolarHBondContact OG-N 3.12Å; S277-L281 PolarHBondContact O-N 2.63Å
278S87Confident93.1Very high34 Ų3447.3 Ų47.324%0.23825%0.248CC..Hα-helixtrans-63.8-25.7175.170.70000112.9S276 K282 Y320S276-S278 PolarHBondContact O-N 2.72Å; S276-S278 VanDerWaalsContact O-N 3.14Å; S278-K282 WeakPolarHBondContact O-CG 3.3Å; S278-K282 PolarHBondContact O-N 3.03Å; S278-K282 VanDerWaalsContact O-N 3.14Å; S278-Y320 WeakPolarHBondContact CB-OH 3.38Å; S278-Y320 PolarHBondContact OG-OH 3.19Å
279T86.9Confident93Very high59 Ų5944.2 Ų44.236%0.36223%0.234SC..Hα-helixtrans-65.3-47.8171.6-65.30000110.9S277 L281 K282 I283S277-T279 PolarHBondContact O-N 3.43Å; T279-L281 PolarHBondContact O-N 2.81Å; T279-K282 PolarHBondContact O-N 3.06Å; T279-I283 HydrophobicContact CG2-CD1 3.93Å; T279-I283 WeakPolarHBondContact O-CG1 3.34Å; T279-I283 PolarHBondContact O-N 2.9Å
280L92.8Very high92.9Very high0 Ų044.2 Ų44.20%023%0.234CC..Hα-helixtrans-63.3-41.6177.3-73.5173.1000111.9L245 L248 V267 V270 R271 F274 S277 K282 I283 L284L245-L280 HydrophobicContact CD1-CD1 3.9Å; L245-L280 HydrophobicContact CD1-CG 4.14Å; L248-L280 HydrophobicContact CD2-CD2 3.2Å; L248-L280 HydrophobicContact CD2-CG 4.3Å; V267-L280 HydrophobicContact CG1-CD2 4.17Å; V270-L280 HydrophobicContact CB-CD1 4.47Å; V270-L280 HydrophobicContact CB-CD2 4.22Å; V270-L280 HydrophobicContact CG1-CD1 3.8Å; V270-L280 HydrophobicContact CG1-CD2 3.85Å; V270-L280 HydrophobicContact CG1-CG 4.49Å; R271-L280 HydrophobicContact CB-CD1 4.3Å; F274-L280 HydrophobicContact CB-CD1 3.77Å; S277-L280 PolarHBondContact O-N 3.37Å; S277-L280 VanDerWaalsContact O-N 3.13Å; S277-L280 PolarHBondContact OG-N 3.12Å; L280-K282 VanDerWaalsContact C-N 3.31Å; L280-K282 PolarHBondContact O-N 3.37Å; L280-I283 PolarHBondContact O-N 2.93Å; L280-L284 VanDerWaalsContact O-CB 3.31Å; L280-L284 WeakPolarHBondContact O-CB 3.18Å; L280-L284 PolarHBondContact O-N 2.85Å
281L92.8Very high92.7Very high3 Ų346.9 Ų46.92%0.01625%0.245CC..Hα-helixtrans-53.3-49.8173.8173.765.2000111.1S277 T279 L284 A285 L312 E315 V316S277-L281 PolarHBondContact O-N 2.63Å; T279-L281 PolarHBondContact O-N 2.81Å; L281-L284 PolarHBondContact O-N 3.19Å; L281-A285 VanDerWaalsContact O-CB 3.29Å; L281-A285 WeakPolarHBondContact O-CB 3.31Å; L281-A285 PolarHBondContact O-N 3.07Å; L281-L312 HydrophobicContact CD1-CD2 3.89Å; L281-E315 HydrophobicContact CD1-CB 4.23Å; L281-E315 HydrophobicContact CD1-CG 4.23Å; L281-E315 VanDerWaalsContact CD1-OE2 3.26Å; L281-E315 WeakPolarHBondContact CD1-OE2 3.42Å; L281-E315 HydrophobicContact CD2-CB 4.08Å; L281-E315 HydrophobicContact CD2-CG 3.62Å; L281-E315 WeakPolarHBondContact CD2-OE1 3.2Å; L281-V316 HydrophobicContact CD1-CG2 4.41Å; L281-V316 HydrophobicContact CD2-CG2 4.03Å; L281-V316 HydrophobicContact CG-CG2 3.75Å
282K91.9Very high92.7Very high67 Ų6744.3 Ų44.329%0.29124%0.236SC..Hα-helixtrans-64.7-41.1179.7-76.1171.956.3175.90113.1S278 T279 L280 N286 V316 Y320S278-K282 WeakPolarHBondContact O-CG 3.3Å; S278-K282 PolarHBondContact O-N 3.03Å; S278-K282 VanDerWaalsContact O-N 3.14Å; T279-K282 PolarHBondContact O-N 3.06Å; L280-K282 VanDerWaalsContact C-N 3.31Å; L280-K282 PolarHBondContact O-N 3.37Å; K282-N286 PolarHBondContact O-N 2.67Å; K282-N286 VanDerWaalsContact O-N 3.15Å; K282-N286 PolarHBondContact O-ND2 2.84Å; K282-V316 HydrophobicContact CG-CG1 4.1Å; K282-V316 HydrophobicContact CG-CG2 4.06Å; K282-Y320 HydrophobicContact CD-CD2 3.97Å; K282-Y320 HydrophobicContact CD-CE2 3.49Å; K282-Y320 VanDerWaalsContact CD-CE2 3.49Å; K282-Y320 HydrophobicContact CG-CD2 4.43Å; K282-Y320 HydrophobicContact CG-CE2 4.09Å
283I93.2Very high92.4Very high14 Ų1439.6 Ų39.67%0.07221%0.213CC..Hα-helixtrans-63-50.7177.4-68169.3000109.3L248 N249 I252 V267 T279 L280 A285 N286 L287L248-I283 HydrophobicContact CD2-CD1 4.17Å; L248-I283 HydrophobicContact CG-CD1 4.41Å; N249-I283 WeakPolarHBondContact OD1-CD1 3.25Å; N249-I283 WeakPolarHBondContact OD1-CG1 3.49Å; I252-I283 HydrophobicContact CB-CG2 4.3Å; I252-I283 HydrophobicContact CG1-CG2 4.15Å; I252-I283 HydrophobicContact CG2-CG2 3.79Å; V267-I283 HydrophobicContact CG1-CG2 4.21Å; V267-I283 HydrophobicContact CG2-CG2 3.76Å; T279-I283 HydrophobicContact CG2-CD1 3.93Å; T279-I283 WeakPolarHBondContact O-CG1 3.34Å; T279-I283 PolarHBondContact O-N 2.9Å; L280-I283 PolarHBondContact O-N 2.93Å; I283-A285 PolarHBondContact O-N 2.98Å; I283-N286 PolarHBondContact O-N 3.46Å; I283-L287 HydrophobicContact CG2-CD1 4.16Å; I283-L287 WeakPolarHBondContact O-CG 3.21Å; I283-L287 PolarHBondContact O-N 3.4Å
284L95.2Very high92.1Very high7 Ų738.4 Ų38.44%0.03721%0.212CC..Hα-helixtrans-61.4-46.4-178.4-170.766.2000111.9I264 V267 Q268 R271 L280 L281 N286 L287 Y288 L312I264-L284 HydrophobicContact CG2-CD1 4.46Å; V267-L284 HydrophobicContact CB-CD1 4.19Å; V267-L284 HydrophobicContact CG1-CB 3.85Å; V267-L284 HydrophobicContact CG1-CD1 3.88Å; V267-L284 HydrophobicContact CG1-CG 4.41Å; Q268-L284 HydrophobicContact CG-CD1 3.93Å; R271-L284 VanDerWaalsContact NH1-CD2 3.35Å; L280-L284 VanDerWaalsContact O-CB 3.31Å; L280-L284 WeakPolarHBondContact O-CB 3.18Å; L280-L284 PolarHBondContact O-N 2.85Å; L281-L284 PolarHBondContact O-N 3.19Å; L284-N286 VanDerWaalsContact C-N 3.31Å; L284-N286 PolarHBondContact O-N 3.18Å; L284-L287 WeakPolarHBondContact O-CB 3.28Å; L284-L287 PolarHBondContact O-N 2.89Å; L284-L287 VanDerWaalsContact O-N 3.15Å; L284-Y288 HydrophobicContact CD1-CD2 3.89Å; L284-Y288 HydrophobicContact CD1-CE2 3.57Å; L284-Y288 HydrophobicContact CG-CD2 3.98Å; L284-Y288 HydrophobicContact CG-CE2 3.9Å; L284-Y288 WeakPolarHBondContact O-CD2 3.5Å; L284-Y288 PolarHBondContact O-N 3.01Å; L284-L312 HydrophobicContact CD2-CD1 4.26Å; L284-L312 HydrophobicContact CD2-CD2 4.19Å; L284-L312 HydrophobicContact CG-CD1 4.14Å
285A95.6Very high91.9Very high0 Ų037.7 Ų37.70%021%0.21CC..Hα-helixtrans-54.3-49.3175.300000110.9L281 I283 L287 Y288 K289 L312 F313 V316L281-A285 VanDerWaalsContact O-CB 3.29Å; L281-A285 WeakPolarHBondContact O-CB 3.31Å; L281-A285 PolarHBondContact O-N 3.07Å; I283-A285 PolarHBondContact O-N 2.98Å; A285-L287 VanDerWaalsContact C-N 3.34Å; A285-L287 PolarHBondContact O-N 3.03Å; A285-Y288 PolarHBondContact O-N 2.72Å; A285-K289 PolarHBondContact O-N 3.46Å; A285-L312 HydrophobicContact CB-CB 3.9Å; A285-F313 VanDerWaalsContact C-CE2 3.48Å; A285-F313 HydrophobicContact CB-CD2 3.87Å; A285-F313 HydrophobicContact CB-CE2 3.75Å; A285-F313 HydrophobicContact CB-CG 4.44Å; A285-F313 HydrophobicContact CB-CZ 4.21Å; A285-F313 VanDerWaalsContact O-CE2 3.23Å; A285-F313 WeakPolarHBondContact O-CE2 3.28Å; A285-V316 HydrophobicContact CB-CG2 3.88Å
286N94.1Very high91.6Very high47 Ų4743.3 Ų43.325%0.25123%0.225SC..Hα-helixtrans-61-40.4178.1-82.5-68.7000112.9K282 I283 L284 K289 W290K282-N286 PolarHBondContact O-N 2.67Å; K282-N286 VanDerWaalsContact O-N 3.15Å; K282-N286 PolarHBondContact O-ND2 2.84Å; I283-N286 PolarHBondContact O-N 3.46Å; L284-N286 VanDerWaalsContact C-N 3.31Å; L284-N286 PolarHBondContact O-N 3.18Å; N286-K289 PolarHBondContact O-N 3.31Å; N286-K289 PolarHBondContact OD1-NZ 3.07Å; N286-W290 PolarHBondContact O-N 2.76Å
287L94.7Very high91.5Very high3 Ų344.8 Ų44.82%0.01622%0.219CC..Hα-helixtrans-62.6-45.8176.7-71.9173.9000111.9I252 K256 Y260 A263 I264 V267 I283 L284 A285 K289 W290 K291I252-L287 HydrophobicContact CG2-CD1 3.98Å; I252-L287 HydrophobicContact CG2-CD2 4.15Å; I252-L287 HydrophobicContact CG2-CG 4.41Å; K256-L287 HydrophobicContact CD-CD2 3.56Å; K256-L287 HydrophobicContact CG-CD2 3.37Å; Y260-L287 HydrophobicContact CD1-CD2 4.3Å; A263-L287 HydrophobicContact CB-CD1 4.03Å; A263-L287 HydrophobicContact CB-CD2 3.67Å; A263-L287 WeakPolarHBondContact O-CD1 3.44Å; I264-L287 HydrophobicContact CD1-CB 4.41Å; I264-L287 HydrophobicContact CG1-CB 3.71Å; I264-L287 HydrophobicContact CG1-CD1 4.21Å; V267-L287 HydrophobicContact CB-CD1 4.13Å; V267-L287 HydrophobicContact CG2-CD1 3.67Å; I283-L287 HydrophobicContact CG2-CD1 4.16Å; I283-L287 WeakPolarHBondContact O-CG 3.21Å; I283-L287 PolarHBondContact O-N 3.4Å; L284-L287 WeakPolarHBondContact O-CB 3.28Å; L284-L287 PolarHBondContact O-N 2.89Å; L284-L287 VanDerWaalsContact O-N 3.15Å; A285-L287 VanDerWaalsContact C-N 3.34Å; A285-L287 PolarHBondContact O-N 3.03Å; L287-K289 PolarHBondContact O-N 3.45Å; L287-W290 PolarHBondContact O-N 2.68Å; L287-K291 WeakPolarHBondContact O-CB 3.37Å; L287-K291 PolarHBondContact O-N 3.19Å
288Y95.1Very high91.3Very high13 Ų1346.9 Ų46.95%0.05123%0.228CC..Hα-helixtrans-60.1-45.5176.9-90.6-115.2000111.7I264 Q268 L284 A285 W290 K291 V292 W305 K308 L312I264-Y288 HydrophobicContact CD1-CD2 4.22Å; I264-Y288 HydrophobicContact CD1-CE2 4.34Å; I264-Y288 HydrophobicContact CG1-CD2 4.23Å; I264-Y288 HydrophobicContact CG1-CE2 4.23Å; I264-Y288 HydrophobicContact CG2-CD2 4.48Å; I264-Y288 HydrophobicContact CG2-CE2 3.67Å; Q268-Y288 PolarHBondContact NE2-OH 3.44Å; L284-Y288 HydrophobicContact CD1-CD2 3.89Å; L284-Y288 HydrophobicContact CD1-CE2 3.57Å; L284-Y288 HydrophobicContact CG-CD2 3.98Å; L284-Y288 HydrophobicContact CG-CE2 3.9Å; L284-Y288 WeakPolarHBondContact O-CD2 3.5Å; L284-Y288 PolarHBondContact O-N 3.01Å; A285-Y288 PolarHBondContact O-N 2.72Å; Y288-W290 PolarHBondContact O-N 3.39Å; Y288-K291 WeakPolarHBondContact O-CB 3.4Å; Y288-K291 PolarHBondContact O-N 2.96Å; Y288-V292 WeakPolarHBondContact O-CG2 3.35Å; Y288-V292 PolarHBondContact O-N 3Å; Y288-W305 AromaticContact CD1-CE3 3.54Å; Y288-W305 HydrophobicContact CD1-CE3 3.54Å; Y288-W305 AromaticContact CD1-CZ3 3.64Å; Y288-W305 HydrophobicContact CD1-CZ3 3.64Å; Y288-W305 HydrophobicContact CD2-CZ3 4.3Å; Y288-W305 AromaticContact CE1-CE3 3.55Å; Y288-W305 HydrophobicContact CE1-CE3 3.55Å; Y288-W305 HydrophobicContact CE1-CH2 4.44Å; Y288-W305 AromaticContact CE1-CZ3 3.31Å; Y288-W305 HydrophobicContact CE1-CZ3 3.31Å; Y288-W305 HydrophobicContact CE2-CZ3 4.02Å; Y288-W305 HydrophobicContact CG-CE3 4.24Å; Y288-W305 HydrophobicContact CG-CZ3 4.13Å; Y288-W305 AromaticContact CZ-CZ3 3.53Å; Y288-K308 HydrophobicContact CD1-CB 3.87Å; Y288-K308 HydrophobicContact CE1-CB 3.69Å; Y288-K308 HydrophobicContact CE1-CD 3.87Å; Y288-K308 HydrophobicContact CE1-CG 4.44Å; Y288-L312 HydrophobicContact CD1-CD1 4Å; Y288-L312 HydrophobicContact CD2-CD1 3.96Å; Y288-L312 HydrophobicContact CE1-CD1 4.39Å; Y288-L312 HydrophobicContact CE2-CD1 4.36Å; Y288-L312 HydrophobicContact CG-CD1 3.76Å
289K94.4Very high91.5Very high4 Ų446.9 Ų46.92%0.01723%0.228CC..Hα-helixtrans-57.5-48.5174.7176.1-166.475.1175.70112.1A285 N286 L287 K291 V292 F293 S309 F313 D329 L333A285-K289 PolarHBondContact O-N 3.46Å; N286-K289 PolarHBondContact O-N 3.31Å; N286-K289 PolarHBondContact OD1-NZ 3.07Å; L287-K289 PolarHBondContact O-N 3.45Å; K289-K291 VanDerWaalsContact C-N 3.31Å; K289-K291 PolarHBondContact O-N 3.35Å; K289-V292 WeakPolarHBondContact O-CB 2.81Å; K289-V292 PolarHBondContact O-N 3.36Å; K289-F293 HydrophobicContact CD-CD2 4.49Å; K289-F293 HydrophobicContact CD-CE1 4.48Å; K289-F293 HydrophobicContact CD-CE2 3.71Å; K289-F293 HydrophobicContact CD-CZ 3.71Å; K289-F293 HydrophobicContact CG-CD1 4.17Å; K289-F293 HydrophobicContact CG-CD2 4.07Å; K289-F293 HydrophobicContact CG-CE1 3.67Å; K289-F293 HydrophobicContact CG-CE2 3.58Å; K289-F293 HydrophobicContact CG-CG 4.35Å; K289-F293 HydrophobicContact CG-CZ 3.36Å; K289-F293 VanDerWaalsContact O-CD1 3.3Å; K289-F293 WeakPolarHBondContact O-CD1 3.19Å; K289-F293 WeakPolarHBondContact O-CG 3.47Å; K289-F293 PolarHBondContact O-N 3.18Å; K289-S309 PolarHBondContact N-OG 3.07Å; K289-F313 HydrophobicContact CB-CE2 3.7Å; K289-F313 HydrophobicContact CB-CZ 4.26Å; K289-F313 HydrophobicContact CD-CE2 4.21Å; K289-F313 HydrophobicContact CD-CZ 4Å; K289-F313 HydrophobicContact CG-CE2 4.42Å; K289-D329 HydrophobicContact CD-CB 3.85Å; K289-D329 VanDerWaalsContact CD-CG 3.48Å; K289-D329 WeakPolarHBondContact CD-OD1 3.48Å; K289-D329 IonicContact NZ-OD1 3.46Å; K289-D329 PolarHBondContact NZ-OD1 3.25Å; K289-D329 IonicContact NZ-OD2 3.14Å; K289-D329 PolarHBondContact NZ-OD2 2.98Å; K289-L333 HydrophobicContact CG-CD2 4.38Å
290W92.2Very high91.6Very high103 Ų10354.3 Ų54.339%0.3925%0.249SC..Hα-helixtrans-66.6-34.9-179.6-76119.5000112.6Y260 N286 L287 Y288 F293 S294Y260-W290 HydrophobicContact CD1-CB 3.92Å; Y260-W290 HydrophobicContact CE1-CB 3.32Å; Y260-W290 AromaticContact CE1-CG 4Å; Y260-W290 HydrophobicContact CE1-CG 4Å; Y260-W290 HydrophobicContact CE2-CB 4.43Å; N286-W290 PolarHBondContact O-N 2.76Å; L287-W290 PolarHBondContact O-N 2.68Å; Y288-W290 PolarHBondContact O-N 3.39Å; W290-F293 HydrophobicContact CE3-CB 4.27Å; W290-F293 HydrophobicContact CE3-CD2 4.01Å; W290-F293 HydrophobicContact CZ3-CD2 4.04Å; W290-F293 PolarHBondContact O-N 3.25Å; W290-S294 WeakPolarHBondContact O-CB 3.4Å; W290-S294 PolarHBondContact O-N 3.31Å; W290-S294 PolarHBondContact O-OG 2.82Å
291K92.5Very high91.5Very high56 Ų5659.2 Ų59.224%0.24327%0.272CS..Hα-helixtrans-57.3-50.5169.1-178.766176.9-177.10110.5I264 L287 Y288 K289 F293 S294 M295 W305I264-K291 HydrophobicContact CD1-CB 4.14Å; I264-K291 HydrophobicContact CD1-CG 4.41Å; L287-K291 WeakPolarHBondContact O-CB 3.37Å; L287-K291 PolarHBondContact O-N 3.19Å; Y288-K291 WeakPolarHBondContact O-CB 3.4Å; Y288-K291 PolarHBondContact O-N 2.96Å; K289-K291 VanDerWaalsContact C-N 3.31Å; K289-K291 PolarHBondContact O-N 3.35Å; K291-F293 VanDerWaalsContact C-N 3.33Å; K291-F293 PolarHBondContact O-N 3.34Å; K291-S294 PolarHBondContact O-N 3.06Å; K291-S294 PolarHBondContact O-OG 2.88Å; K291-M295 WeakPolarHBondContact O-CG 3.42Å; K291-M295 PolarHBondContact O-N 3.48Å; K291-W305 HydrophobicContact CG-CD2 4.06Å; K291-W305 HydrophobicContact CG-CE3 4.12Å; K291-W305 HydrophobicContact CG-CZ2 4.49Å; K291-W305 HydrophobicContact CG-CZ3 4.36Å
292V93.2Very high91.5Very high0 Ų060.1 Ų60.10%028%0.275CS..Hα-helixtrans-57.7-41.6175.5171.20000112.8Y288 K289 S294 M295 R302 W305 V306 L333 Y336Y288-V292 WeakPolarHBondContact O-CG2 3.35Å; Y288-V292 PolarHBondContact O-N 3Å; K289-V292 WeakPolarHBondContact O-CB 2.81Å; K289-V292 PolarHBondContact O-N 3.36Å; V292-S294 VanDerWaalsContact C-N 3.33Å; V292-M295 PolarHBondContact O-N 3.15Å; V292-R302 PolarHBondContact O-NH2 3.49Å; V292-R302 VanDerWaalsContact O-NH2 3.08Å; V292-W305 HydrophobicContact CG2-CB 3.67Å; V292-V306 HydrophobicContact CB-CG2 4.48Å; V292-V306 HydrophobicContact CG1-CG2 3.5Å; V292-V306 HydrophobicContact CG2-CG2 4.08Å; V292-L333 HydrophobicContact CB-CD2 4.49Å; V292-L333 HydrophobicContact CG1-CD2 4.28Å; V292-Y336 HydrophobicContact CG1-CD2 4.28Å; V292-Y336 HydrophobicContact CG1-CG 4.19Å
293F90Very high91.5Very high56 Ų5663.6 Ų63.625%0.24629%0.287CS..Hα-helixtrans-72.2-28.7-177.4-69.55.3000112.2K289 W290 K291 M295 L333 Y336K289-F293 HydrophobicContact CD-CD2 4.49Å; K289-F293 HydrophobicContact CD-CE1 4.48Å; K289-F293 HydrophobicContact CD-CE2 3.71Å; K289-F293 HydrophobicContact CD-CZ 3.71Å; K289-F293 HydrophobicContact CG-CD1 4.17Å; K289-F293 HydrophobicContact CG-CD2 4.07Å; K289-F293 HydrophobicContact CG-CE1 3.67Å; K289-F293 HydrophobicContact CG-CE2 3.58Å; K289-F293 HydrophobicContact CG-CG 4.35Å; K289-F293 HydrophobicContact CG-CZ 3.36Å; K289-F293 VanDerWaalsContact O-CD1 3.3Å; K289-F293 WeakPolarHBondContact O-CD1 3.19Å; K289-F293 WeakPolarHBondContact O-CG 3.47Å; K289-F293 PolarHBondContact O-N 3.18Å; W290-F293 HydrophobicContact CE3-CB 4.27Å; W290-F293 HydrophobicContact CE3-CD2 4.01Å; W290-F293 HydrophobicContact CZ3-CD2 4.04Å; W290-F293 PolarHBondContact O-N 3.25Å; K291-F293 VanDerWaalsContact C-N 3.33Å; K291-F293 PolarHBondContact O-N 3.34Å; F293-M295 VanDerWaalsContact C-N 3.34Å; F293-L333 HydrophobicContact CE1-CD2 4.22Å; F293-Y336 HydrophobicContact CD1-CD2 4.02Å; F293-Y336 AromaticContact CD1-CE2 3.37Å; F293-Y336 HydrophobicContact CD1-CE2 3.37Å; F293-Y336 AromaticContact CD1-CZ 3.99Å; F293-Y336 AromaticContact CE1-CD2 3.68Å; F293-Y336 HydrophobicContact CE1-CD2 3.68Å; F293-Y336 AromaticContact CE1-CE2 3.27Å; F293-Y336 HydrophobicContact CE1-CE2 3.27Å; F293-Y336 HydrophobicContact CG-CE2 4.39Å; F293-Y336 HydrophobicContact CZ-CE2 4.2Å
294S89.3Confident91.5Very high64 Ų6467 Ų6745%0.44830%0.304SS..Hα-helixtrans-73.7-21.7175.571.10000114W290 K291 V292 K296W290-S294 WeakPolarHBondContact O-CB 3.4Å; W290-S294 PolarHBondContact O-N 3.31Å; W290-S294 PolarHBondContact O-OG 2.82Å; K291-S294 PolarHBondContact O-N 3.06Å; K291-S294 PolarHBondContact O-OG 2.88Å; V292-S294 VanDerWaalsContact C-N 3.33Å; S294-K296 PolarHBondContact O-N 3.25Å
295M90.1Very high91.5Very high27 Ų2768.8 Ų68.813%0.13331%0.31CS..  trans-76118.9179.9-65.617387.800110.3K291 V292 F293 E301 R302 W305K291-M295 WeakPolarHBondContact O-CG 3.42Å; K291-M295 PolarHBondContact O-N 3.48Å; V292-M295 PolarHBondContact O-N 3.15Å; F293-M295 VanDerWaalsContact C-N 3.34Å; M295-E301 HydrophobicContact CE-CB 4.07Å; M295-E301 HydrophobicContact CE-CG 4.08Å; M295-R302 HydrophobicContact CB-CG 4.2Å; M295-R302 HydrophobicContact CE-CB 3.78Å; M295-R302 HydrophobicContact CE-CG 4.47Å; M295-R302 PolarHBondContact O-NH1 3.03Å; M295-R302 PolarHBondContact O-NH2 2.91Å; M295-R302 HydrophobicContact SD-CB 4.01Å; M295-R302 HydrophobicContact SD-CG 4.06Å; M295-W305 HydrophobicContact SD-CB 4.49Å; M295-W305 HydrophobicContact SD-CG 4.33Å
296K85.1Confident91.5Very high208 Ų20869 Ų6990%0.90431%0.311SS*.  trans-77.5-42.2-178.8-65.4-174.3-179.8179.30112.3S294S294-K296 PolarHBondContact O-N 3.25Å
297E86.3Confident91.6Very high149 Ų14971.3 Ų71.370%0.69632%0.321SS*.SBendtrans-84.8140.1-174.9-64.6176-175.500112S299 R302E297-S299 PolarHBondContact O-N 3.36Å; E297-R302 WeakPolarHBondContact O-CD 3.47Å
298D85.3Confident91.6Very high71 Ų7175.5 Ų75.538%0.3834%0.339SS..  trans-77.675.1164.9-177.311000109.8R303 H338D298-R303 IonicContact OD1-CZ 2.74Å; D298-R303 IonicContact OD1-NE 2.75Å; D298-R303 PolarHBondContact OD1-NE 3.12Å; D298-R303 IonicContact OD1-NH2 3.9Å; D298-R303 PolarHBondContact OD1-NH2 3.07Å; D298-R303 IonicContact OD2-CZ 3.82Å; D298-R303 IonicContact OD2-NE 3.51Å; D298-R303 IonicContact OD2-NH2 2.7Å; D298-R303 PolarHBondContact OD2-NH2 2.75Å; D298-H338 IonicContact OD2-CE1 3.31Å; D298-H338 IonicContact OD2-NE2 3.54Å; D298-H338 PolarHBondContact OD2-NE2 3.26Å
299S90.2Very high91.7Very high33 Ų3374.9 Ų74.923%0.23134%0.337CS..  trans-92.8162.3178.373.20000111.9E297 E301 R302 R303E297-S299 PolarHBondContact O-N 3.36Å; S299-E301 PolarHBondContact O-N 3.37Å; S299-E301 PolarHBondContact OG-N 2.78Å; S299-R302 WeakPolarHBondContact O-CB 3.26Å; S299-R302 PolarHBondContact O-N 3.42Å; S299-R302 PolarHBondContact OG-N 2.88Å; S299-R303 PolarHBondContact O-N 3.17Å; S299-R303 VanDerWaalsContact O-N 3.17Å
300R89.8Confident91.8Very high215 Ų21575 Ų7581%0.81134%0.337SS*.Hα-helixtrans-53.8-38.8170.8-177.5179.3179.2-174.70.6111.7R303 I304R300-R303 PolarHBondContact O-N 3Å; R300-I304 WeakPolarHBondContact O-CG1 3.12Å; R300-I304 PolarHBondContact O-N 2.95Å
301E91.1Very high92.1Very high103 Ų10374.8 Ų74.848%0.48134%0.341SS..Hα-helixtrans-61.3-46176.7-164.7-161.2160.500111.1M295 S299 R303 I304 W305M295-E301 HydrophobicContact CE-CB 4.07Å; M295-E301 HydrophobicContact CE-CG 4.08Å; S299-E301 PolarHBondContact O-N 3.37Å; S299-E301 PolarHBondContact OG-N 2.78Å; E301-R303 VanDerWaalsContact C-N 3.28Å; E301-R303 PolarHBondContact O-N 3.25Å; E301-I304 WeakPolarHBondContact O-CB 3.24Å; E301-I304 PolarHBondContact O-N 3.41Å; E301-I304 VanDerWaalsContact O-N 3.15Å; E301-W305 PolarHBondContact O-N 3.4Å; E301-W305 VanDerWaalsContact O-N 3.09Å; E301-W305 PolarHBondContact OE1-NE1 3.36Å
302R91.8Very high92.2Very high23 Ų2373 Ų739%0.08733%0.334CS..Hα-helixtrans-58.2-42.3178-173.1-177.3-170.3160.324.4111.5V292 M295 E297 S299 I304 W305 V306 Y336V292-R302 PolarHBondContact O-NH2 3.49Å; V292-R302 VanDerWaalsContact O-NH2 3.08Å; M295-R302 HydrophobicContact CB-CG 4.2Å; M295-R302 HydrophobicContact CE-CB 3.78Å; M295-R302 HydrophobicContact CE-CG 4.47Å; M295-R302 PolarHBondContact O-NH1 3.03Å; M295-R302 PolarHBondContact O-NH2 2.91Å; M295-R302 HydrophobicContact SD-CB 4.01Å; M295-R302 HydrophobicContact SD-CG 4.06Å; E297-R302 WeakPolarHBondContact O-CD 3.47Å; S299-R302 WeakPolarHBondContact O-CB 3.26Å; S299-R302 PolarHBondContact O-N 3.42Å; S299-R302 PolarHBondContact OG-N 2.88Å; R302-I304 VanDerWaalsContact C-N 3.3Å; R302-I304 PolarHBondContact O-N 3.43Å; R302-W305 PolarHBondContact O-N 3.44Å; R302-W305 VanDerWaalsContact O-N 3.15Å; R302-V306 HydrophobicContact CG-CG2 4.19Å; R302-V306 VanDerWaalsContact O-CG2 3.25Å; R302-V306 WeakPolarHBondContact O-CG2 3.46Å; R302-V306 PolarHBondContact O-N 2.93Å; R302-Y336 VanDerWaalsContact CZ-CE1 3.49Å
303R92.2Very high92.4Very high140 Ų14073.2 Ų73.253%0.52833%0.334SS..Hα-helixtrans-62-38179.3-63.3-177.5-169.4-161.11112.4D298 S299 R300 E301 V306 Q307D298-R303 IonicContact OD1-CZ 2.74Å; D298-R303 IonicContact OD1-NE 2.75Å; D298-R303 PolarHBondContact OD1-NE 3.12Å; D298-R303 IonicContact OD1-NH2 3.9Å; D298-R303 PolarHBondContact OD1-NH2 3.07Å; D298-R303 IonicContact OD2-CZ 3.82Å; D298-R303 IonicContact OD2-NE 3.51Å; D298-R303 IonicContact OD2-NH2 2.7Å; D298-R303 PolarHBondContact OD2-NH2 2.75Å; S299-R303 PolarHBondContact O-N 3.17Å; S299-R303 VanDerWaalsContact O-N 3.17Å; R300-R303 PolarHBondContact O-N 3Å; E301-R303 VanDerWaalsContact C-N 3.28Å; E301-R303 PolarHBondContact O-N 3.25Å; R303-V306 PolarHBondContact O-N 3.4Å; R303-Q307 PolarHBondContact O-N 3.45Å
304I93.4Very high92.7Very high84 Ų8474.3 Ų74.343%0.43134%0.34SS..Hα-helixtrans-63.3-45.8173.9-64.1166.8000110.5R300 E301 R302 Q307 K308R300-I304 WeakPolarHBondContact O-CG1 3.12Å; R300-I304 PolarHBondContact O-N 2.95Å; E301-I304 WeakPolarHBondContact O-CB 3.24Å; E301-I304 PolarHBondContact O-N 3.41Å; E301-I304 VanDerWaalsContact O-N 3.15Å; R302-I304 VanDerWaalsContact C-N 3.3Å; R302-I304 PolarHBondContact O-N 3.43Å; I304-Q307 PolarHBondContact O-N 3.46Å; I304-K308 HydrophobicContact CG2-CD 4.4Å; I304-K308 WeakPolarHBondContact O-CG 3.35Å; I304-K308 PolarHBondContact O-N 2.95Å; I304-K308 VanDerWaalsContact O-N 3.1Å
305W94.2Very high93Very high46 Ų4674 Ų7417%0.17433%0.332CS..Hα-helixtrans-63.4-40.5176.9-76.3108.7000112.7I264 Y288 K291 V292 M295 E301 R302 S309I264-W305 HydrophobicContact CD1-CH2 4.11Å; I264-W305 HydrophobicContact CD1-CZ3 3.92Å; Y288-W305 AromaticContact CD1-CE3 3.54Å; Y288-W305 HydrophobicContact CD1-CE3 3.54Å; Y288-W305 AromaticContact CD1-CZ3 3.64Å; Y288-W305 HydrophobicContact CD1-CZ3 3.64Å; Y288-W305 HydrophobicContact CD2-CZ3 4.3Å; Y288-W305 AromaticContact CE1-CE3 3.55Å; Y288-W305 HydrophobicContact CE1-CE3 3.55Å; Y288-W305 HydrophobicContact CE1-CH2 4.44Å; Y288-W305 AromaticContact CE1-CZ3 3.31Å; Y288-W305 HydrophobicContact CE1-CZ3 3.31Å; Y288-W305 HydrophobicContact CE2-CZ3 4.02Å; Y288-W305 HydrophobicContact CG-CE3 4.24Å; Y288-W305 HydrophobicContact CG-CZ3 4.13Å; Y288-W305 AromaticContact CZ-CZ3 3.53Å; K291-W305 HydrophobicContact CG-CD2 4.06Å; K291-W305 HydrophobicContact CG-CE3 4.12Å; K291-W305 HydrophobicContact CG-CZ2 4.49Å; K291-W305 HydrophobicContact CG-CZ3 4.36Å; V292-W305 HydrophobicContact CG2-CB 3.67Å; M295-W305 HydrophobicContact SD-CB 4.49Å; M295-W305 HydrophobicContact SD-CG 4.33Å; E301-W305 PolarHBondContact O-N 3.4Å; E301-W305 VanDerWaalsContact O-N 3.09Å; E301-W305 PolarHBondContact OE1-NE1 3.36Å; R302-W305 PolarHBondContact O-N 3.44Å; R302-W305 VanDerWaalsContact O-N 3.15Å; W305-S309 VanDerWaalsContact O-CB 3.24Å; W305-S309 WeakPolarHBondContact O-CB 3.48Å; W305-S309 PolarHBondContact O-N 2.86Å
306V96.2Very high93.2Very high3 Ų373 Ų732%0.01833%0.327CS..Hα-helixtrans-59.1-50175.51700000110.1V292 R302 R303 K308 S309 I310 A337V292-V306 HydrophobicContact CB-CG2 4.48Å; V292-V306 HydrophobicContact CG1-CG2 3.5Å; V292-V306 HydrophobicContact CG2-CG2 4.08Å; R302-V306 HydrophobicContact CG-CG2 4.19Å; R302-V306 VanDerWaalsContact O-CG2 3.25Å; R302-V306 WeakPolarHBondContact O-CG2 3.46Å; R302-V306 PolarHBondContact O-N 2.93Å; R303-V306 PolarHBondContact O-N 3.4Å; V306-K308 PolarHBondContact O-N 3.29Å; V306-S309 WeakPolarHBondContact O-CB 3.31Å; V306-S309 PolarHBondContact O-N 2.92Å; V306-S309 VanDerWaalsContact O-N 3.13Å; V306-I310 HydrophobicContact CG1-CD1 3.84Å; V306-I310 HydrophobicContact CG1-CG1 4.41Å; V306-I310 WeakPolarHBondContact O-CG1 3.47Å; V306-I310 PolarHBondContact O-N 3.19Å; V306-A337 HydrophobicContact CG1-CB 3.68Å
307Q96.1Very high93.7Very high96 Ų9664.4 Ų64.445%0.44929%0.292SS..Hα-helixtrans-60-49.5-178.7-176.155.339.200111.9R303 I304 S309 I310 E311R303-Q307 PolarHBondContact O-N 3.45Å; I304-Q307 PolarHBondContact O-N 3.46Å; Q307-S309 VanDerWaalsContact C-N 3.26Å; Q307-S309 PolarHBondContact O-N 2.95Å; Q307-I310 PolarHBondContact O-N 3.13Å; Q307-I310 VanDerWaalsContact O-N 3.15Å; Q307-E311 WeakPolarHBondContact CG-OE1 3.39Å; Q307-E311 PolarHBondContact NE2-OE1 2.97Å; Q307-E311 PolarHBondContact O-N 3.41Å; Q307-E311 VanDerWaalsContact O-N 3.09Å
308K95.1Very high94.1Very high92 Ų9265.3 Ų65.340%0.429%0.289SS..Hα-helixtrans-59.5-38.3175-68.8-179179.9-177.20112.4Y288 I304 V306 L312Y288-K308 HydrophobicContact CD1-CB 3.87Å; Y288-K308 HydrophobicContact CE1-CB 3.69Å; Y288-K308 HydrophobicContact CE1-CD 3.87Å; Y288-K308 HydrophobicContact CE1-CG 4.44Å; I304-K308 HydrophobicContact CG2-CD 4.4Å; I304-K308 WeakPolarHBondContact O-CG 3.35Å; I304-K308 PolarHBondContact O-N 2.95Å; I304-K308 VanDerWaalsContact O-N 3.1Å; V306-K308 PolarHBondContact O-N 3.29Å; K308-L312 WeakPolarHBondContact O-CG 3.19Å; K308-L312 PolarHBondContact O-N 3.03Å
309S96.9Very high94.4Very high0 Ų066 Ų660%029%0.29CS..Hα-helixtrans-68.4-37.1178.1-168.20000111.9K289 W305 V306 Q307 F313 L333K289-S309 PolarHBondContact N-OG 3.07Å; W305-S309 VanDerWaalsContact O-CB 3.24Å; W305-S309 WeakPolarHBondContact O-CB 3.48Å; W305-S309 PolarHBondContact O-N 2.86Å; V306-S309 WeakPolarHBondContact O-CB 3.31Å; V306-S309 PolarHBondContact O-N 2.92Å; V306-S309 VanDerWaalsContact O-N 3.13Å; Q307-S309 VanDerWaalsContact C-N 3.26Å; Q307-S309 PolarHBondContact O-N 2.95Å; S309-F313 WeakPolarHBondContact O-CB 3.27Å; S309-F313 WeakPolarHBondContact O-CD2 3.22Å; S309-F313 PolarHBondContact O-N 2.83Å; S309-L333 WeakPolarHBondContact OG-CD1 3.47Å; S309-L333 WeakPolarHBondContact OG-CD2 3.3Å
310I97.9Very high94.4Very high5 Ų565.4 Ų65.43%0.02628%0.283CS..Hα-helixtrans-62.2-51175.4-72.6170.2000109.6V306 Q307 L312 F313 E314 L330 L333 A337V306-I310 HydrophobicContact CG1-CD1 3.84Å; V306-I310 HydrophobicContact CG1-CG1 4.41Å; V306-I310 WeakPolarHBondContact O-CG1 3.47Å; V306-I310 PolarHBondContact O-N 3.19Å; Q307-I310 PolarHBondContact O-N 3.13Å; Q307-I310 VanDerWaalsContact O-N 3.15Å; I310-L312 VanDerWaalsContact C-N 3.31Å; I310-L312 PolarHBondContact O-N 2.67Å; I310-F313 CarbonylContact O-C 3.27Å; I310-F313 PolarHBondContact O-N 3.07Å; I310-E314 HydrophobicContact CG2-CG 4.16Å; I310-E314 WeakPolarHBondContact O-CG 3.44Å; I310-E314 PolarHBondContact O-N 3.23Å; I310-L330 HydrophobicContact CG2-CD1 4.15Å; I310-L333 HydrophobicContact CD1-CB 4.47Å; I310-L333 HydrophobicContact CG1-CB 3.73Å; I310-A337 HydrophobicContact CD1-CB 3.79Å
311E96.6Very high94.5Very high100 Ų10057.7 Ų57.747%0.46726%0.26SS..Hα-helixtrans-54.7-46179.4-70.5162.1-163.200112.1Q307 E314 E315Q307-E311 WeakPolarHBondContact CG-OE1 3.39Å; Q307-E311 PolarHBondContact NE2-OE1 2.97Å; Q307-E311 PolarHBondContact O-N 3.41Å; Q307-E311 VanDerWaalsContact O-N 3.09Å; E311-E314 PolarHBondContact O-N 3.49Å; E311-E315 PolarHBondContact O-N 3.34Å; E311-E315 VanDerWaalsContact O-N 3.14Å
312L96.4Very high94.6Very high19 Ų1953.7 Ų53.710%0.09924%0.243CC..Hα-helixtrans-63.9-41.2176.4-69.8170.8000112.3L281 L284 A285 Y288 K308 I310 E315 V316L281-L312 HydrophobicContact CD1-CD2 3.89Å; L284-L312 HydrophobicContact CD2-CD1 4.26Å; L284-L312 HydrophobicContact CD2-CD2 4.19Å; L284-L312 HydrophobicContact CG-CD1 4.14Å; A285-L312 HydrophobicContact CB-CB 3.9Å; Y288-L312 HydrophobicContact CD1-CD1 4Å; Y288-L312 HydrophobicContact CD2-CD1 3.96Å; Y288-L312 HydrophobicContact CE1-CD1 4.39Å; Y288-L312 HydrophobicContact CE2-CD1 4.36Å; Y288-L312 HydrophobicContact CG-CD1 3.76Å; K308-L312 WeakPolarHBondContact O-CG 3.19Å; K308-L312 PolarHBondContact O-N 3.03Å; I310-L312 VanDerWaalsContact C-N 3.31Å; I310-L312 PolarHBondContact O-N 2.67Å; L312-E315 PolarHBondContact O-N 2.93Å; L312-V316 WeakPolarHBondContact O-CG2 3.13Å; L312-V316 PolarHBondContact O-N 3.5Å
313F97.1Very high94.6Very high3 Ų354.9 Ų54.91%0.01325%0.254CS..Hα-helixtrans-74.2-32179.7-95-85.5000113.2A285 K289 S309 I310 E315 V316 V317 D329 L330 L333A285-F313 VanDerWaalsContact C-CE2 3.48Å; A285-F313 HydrophobicContact CB-CD2 3.87Å; A285-F313 HydrophobicContact CB-CE2 3.75Å; A285-F313 HydrophobicContact CB-CG 4.44Å; A285-F313 HydrophobicContact CB-CZ 4.21Å; A285-F313 VanDerWaalsContact O-CE2 3.23Å; A285-F313 WeakPolarHBondContact O-CE2 3.28Å; K289-F313 HydrophobicContact CB-CE2 3.7Å; K289-F313 HydrophobicContact CB-CZ 4.26Å; K289-F313 HydrophobicContact CD-CE2 4.21Å; K289-F313 HydrophobicContact CD-CZ 4Å; K289-F313 HydrophobicContact CG-CE2 4.42Å; S309-F313 WeakPolarHBondContact O-CB 3.27Å; S309-F313 WeakPolarHBondContact O-CD2 3.22Å; S309-F313 PolarHBondContact O-N 2.83Å; I310-F313 CarbonylContact O-C 3.27Å; I310-F313 PolarHBondContact O-N 3.07Å; F313-E315 VanDerWaalsContact C-N 3.3Å; F313-V316 PolarHBondContact O-N 3.3Å; F313-V317 WeakPolarHBondContact O-CB 3.37Å; F313-V317 VanDerWaalsContact O-CG2 3.3Å; F313-V317 WeakPolarHBondContact O-CG2 3.46Å; F313-V317 PolarHBondContact O-N 2.91Å; F313-D329 HydrophobicContact CD1-CB 3.94Å; F313-D329 HydrophobicContact CE1-CB 3.37Å; F313-D329 HydrophobicContact CZ-CB 3.73Å; F313-L330 HydrophobicContact CB-CB 4.21Å; F313-L330 HydrophobicContact CB-CD1 3.89Å; F313-L333 HydrophobicContact CB-CD1 4.11Å; F313-L333 HydrophobicContact CD2-CD1 3.4Å; F313-L333 VanDerWaalsContact CD2-CD1 3.4Å; F313-L333 HydrophobicContact CE2-CD1 4Å; F313-L333 HydrophobicContact CG-CD1 3.88Å
314E96.6Very high94.7Very high79 Ų7948.5 Ų48.537%0.36923%0.23SC..Hα-helixtrans-60.5-43.3170-73.9179.7167.700110.5I310 E311 V317 R318 L330I310-E314 HydrophobicContact CG2-CG 4.16Å; I310-E314 WeakPolarHBondContact O-CG 3.44Å; I310-E314 PolarHBondContact O-N 3.23Å; E311-E314 PolarHBondContact O-N 3.49Å; E314-V317 PolarHBondContact O-N 3.48Å; E314-R318 WeakPolarHBondContact O-CB 3.33Å; E314-R318 PolarHBondContact O-N 2.99Å; E314-L330 HydrophobicContact CG-CD1 4.06Å; E314-L330 HydrophobicContact CG-CD2 4.24Å
315E95.5Very high94.7Very high57 Ų5749.5 Ų49.527%0.26623%0.231SC..Hα-helixtrans-62.5-44.5173.5-163.4-171.6161.600111.6R271 L281 E311 L312 F313 R318 H319R271-E315 IonicContact NH2-OE1 4Å; R271-E315 IonicContact NH2-OE2 3Å; R271-E315 PolarHBondContact NH2-OE2 3.1Å; L281-E315 HydrophobicContact CD1-CB 4.23Å; L281-E315 HydrophobicContact CD1-CG 4.23Å; L281-E315 VanDerWaalsContact CD1-OE2 3.26Å; L281-E315 WeakPolarHBondContact CD1-OE2 3.42Å; L281-E315 HydrophobicContact CD2-CB 4.08Å; L281-E315 HydrophobicContact CD2-CG 3.62Å; L281-E315 WeakPolarHBondContact CD2-OE1 3.2Å; E311-E315 PolarHBondContact O-N 3.34Å; E311-E315 VanDerWaalsContact O-N 3.14Å; L312-E315 PolarHBondContact O-N 2.93Å; F313-E315 VanDerWaalsContact C-N 3.3Å; E315-R318 WeakPolarHBondContact O-CB 3.34Å; E315-R318 PolarHBondContact O-N 3.23Å; E315-H319 PolarHBondContact O-N 3.38Å; E315-H319 PolarHBondContact O-ND1 2.85Å; E315-H319 IonicContact OE1-CE1 2.76Å
316V94.6Very high94.8Very high7 Ų747.4 Ų47.44%0.04223%0.225CC..Hα-helixtrans-60.8-46.7175.9169.70000111.6L281 K282 A285 L312 F313 R318 H319 Y320L281-V316 HydrophobicContact CD1-CG2 4.41Å; L281-V316 HydrophobicContact CD2-CG2 4.03Å; L281-V316 HydrophobicContact CG-CG2 3.75Å; K282-V316 HydrophobicContact CG-CG1 4.1Å; K282-V316 HydrophobicContact CG-CG2 4.06Å; A285-V316 HydrophobicContact CB-CG2 3.88Å; L312-V316 WeakPolarHBondContact O-CG2 3.13Å; L312-V316 PolarHBondContact O-N 3.5Å; F313-V316 PolarHBondContact O-N 3.3Å; V316-R318 VanDerWaalsContact C-N 3.29Å; V316-R318 PolarHBondContact O-N 3.35Å; V316-H319 PolarHBondContact O-N 3.2Å; V316-Y320 HydrophobicContact CG1-CD2 4.28Å; V316-Y320 WeakPolarHBondContact O-CB 3.35Å; V316-Y320 WeakPolarHBondContact O-CD2 3.35Å; V316-Y320 PolarHBondContact O-N 3.43Å
317V95.2Very high94.8Very high27 Ų2748.1 Ų48.116%0.16423%0.227CC..Hα-helixtrans-66.7-33.4-178.8169.60000111F313 E314 H319 Y320 P321 R327 L330F313-V317 WeakPolarHBondContact O-CB 3.37Å; F313-V317 VanDerWaalsContact O-CG2 3.3Å; F313-V317 WeakPolarHBondContact O-CG2 3.46Å; F313-V317 PolarHBondContact O-N 2.91Å; E314-V317 PolarHBondContact O-N 3.48Å; V317-H319 PolarHBondContact O-N 3.03Å; V317-Y320 CarbonylContact O-C 3.57Å; V317-Y320 VanDerWaalsContact O-C 3.27Å; V317-Y320 PolarHBondContact O-N 3.36Å; V317-P321 VanDerWaalsContact O-CA 3.26Å; V317-P321 WeakPolarHBondContact O-CA 3.33Å; V317-R327 HydrophobicContact CG1-CG 3.76Å; V317-R327 HydrophobicContact CG2-CG 3.95Å; V317-L330 HydrophobicContact CB-CD2 4.39Å; V317-L330 HydrophobicContact CG2-CB 4.42Å; V317-L330 HydrophobicContact CG2-CD2 4.03Å
318R94.1Very high94.8Very high168 Ų16843.6 Ų43.663%0.63421%0.206SC*.Hα-helixtrans-61.4-42.1173.5-166.2-174.7-54.2119.45.8112.4E314 E315 V316E314-R318 WeakPolarHBondContact O-CB 3.33Å; E314-R318 PolarHBondContact O-N 2.99Å; E315-R318 WeakPolarHBondContact O-CB 3.34Å; E315-R318 PolarHBondContact O-N 3.23Å; V316-R318 VanDerWaalsContact C-N 3.29Å; V316-R318 PolarHBondContact O-N 3.35Å
319H90.7Very high94.9Very high85 Ų8540.1 Ų40.139%0.39419%0.192SC..Hα-helixtrans-78.8-28.4177.7-67.792.5000112.9E315 V316 V317 P321E315-H319 PolarHBondContact O-N 3.38Å; E315-H319 PolarHBondContact O-ND1 2.85Å; E315-H319 IonicContact OE1-CE1 2.76Å; V316-H319 PolarHBondContact O-N 3.2Å; V317-H319 PolarHBondContact O-N 3.03Å; H319-P321 VanDerWaalsContact C-CD 3.49Å
320Y91.7Very high94.9Very high21 Ų2140.6 Ų40.68%0.08219%0.194CC..  trans-131.764.2-173.7-56.3-80.7000111.6S278 K282 V316 V317 D322 C323S278-Y320 WeakPolarHBondContact CB-OH 3.38Å; S278-Y320 PolarHBondContact OG-OH 3.19Å; K282-Y320 HydrophobicContact CD-CD2 3.97Å; K282-Y320 HydrophobicContact CD-CE2 3.49Å; K282-Y320 VanDerWaalsContact CD-CE2 3.49Å; K282-Y320 HydrophobicContact CG-CD2 4.43Å; K282-Y320 HydrophobicContact CG-CE2 4.09Å; V316-Y320 HydrophobicContact CG1-CD2 4.28Å; V316-Y320 WeakPolarHBondContact O-CB 3.35Å; V316-Y320 WeakPolarHBondContact O-CD2 3.35Å; V316-Y320 PolarHBondContact O-N 3.43Å; V317-Y320 CarbonylContact O-C 3.57Å; V317-Y320 VanDerWaalsContact O-C 3.27Å; V317-Y320 PolarHBondContact O-N 3.36Å; Y320-D322 VanDerWaalsContact C-N 3.26Å; Y320-D322 PolarHBondContact O-N 2.84Å; Y320-C323 WeakPolarHBondContact O-CB 3.22Å; Y320-C323 PolarHBondContact O-N 3.44Å
321P92.4Very high94.9Very high53 Ų5340.4 Ų40.434%0.34419%0.193SC..THydrogen-bonded Turntrans-62.2-31.4-174.823.5-34.5000113.3V317 H319 C323 R327V317-P321 VanDerWaalsContact O-CA 3.26Å; V317-P321 WeakPolarHBondContact O-CA 3.33Å; H319-P321 VanDerWaalsContact C-CD 3.49Å; P321-C323 PolarHBondContact O-N 2.74Å; P321-R327 WeakPolarHBondContact O-CD 3.45Å
322D91.6Very high94.8Very high20 Ų2036.7 Ų36.711%0.10718%0.178CC..THydrogen-bonded Turntrans-73.4-9.7177.8-54.6-2.1000113.1N25 Q28 G29 R32 Y320 V324N25-D322 WeakPolarHBondContact ND2-CA 3.32Å; N25-D322 WeakPolarHBondContact ND2-CB 3.46Å; N25-D322 PolarHBondContact ND2-O 2.93Å; N25-D322 PolarHBondContact OD1-O 2.85Å; N25-D322 VanDerWaalsContact OD1-O 3.09Å; Q28-D322 VanDerWaalsContact C-OD2 3.24Å; Q28-D322 WeakPolarHBondContact CB-OD2 3.2Å; G29-D322 PolarHBondContact N-OD2 3.2Å; R32-D322 IonicContact CZ-OD1 2.77Å; R32-D322 IonicContact CZ-OD2 3.96Å; R32-D322 VanDerWaalsContact NH1-CG 3.29Å; R32-D322 IonicContact NH1-OD1 3.74Å; R32-D322 PolarHBondContact NH1-OD1 2.92Å; R32-D322 VanDerWaalsContact NH1-OD1 3.15Å; R32-D322 IonicContact NH1-OD2 3.31Å; R32-D322 PolarHBondContact NH1-OD2 3.36Å; R32-D322 VanDerWaalsContact NH2-CB 3.32Å; R32-D322 IonicContact NH2-OD1 3.92Å; R32-D322 PolarHBondContact NH2-OD1 3.48Å; R32-D322 IonicContact NH2-OD2 3.96Å; R32-D322 PolarHBondContact NH2-OD2 3.27Å; Y320-D322 VanDerWaalsContact C-N 3.26Å; Y320-D322 PolarHBondContact O-N 2.84Å; D322-V324 PolarHBondContact O-N 3.35Å
323C91.4Very high94.8Very high48 Ų4835.8 Ų35.832%0.32417%0.174SC..  trans-74.390.8-176.4-171.60000111Y320 P321 K325 G326 R327Y320-C323 WeakPolarHBondContact O-CB 3.22Å; Y320-C323 PolarHBondContact O-N 3.44Å; P321-C323 PolarHBondContact O-N 2.74Å; C323-K325 PolarHBondContact O-N 3.41Å; C323-G326 WeakPolarHBondContact O-CA 3.31Å; C323-G326 PolarHBondContact O-N 3.03Å; C323-G326 PolarHBondContact SG-N 3.15Å; C323-G326 VanDerWaalsContact SG-N 3.4Å; C323-R327 PolarHBondContact O-N 3.46Å
324V94.8Very high94.8Very high5 Ų536.2 Ų36.23%0.0318%0.176CC..Hα-helixtrans-50-42.8176.6177.80000111.7D322 G326 R327 S328 L350 L357 L364 L365D322-V324 PolarHBondContact O-N 3.35Å; V324-G326 PolarHBondContact O-N 3.33Å; V324-R327 PolarHBondContact O-N 3.42Å; V324-S328 VanDerWaalsContact O-CB 3.31Å; V324-S328 WeakPolarHBondContact O-CB 3.43Å; V324-S328 PolarHBondContact O-N 3.07Å; V324-S328 PolarHBondContact O-OG 3.43Å; V324-L350 HydrophobicContact CG1-CD2 4.34Å; V324-L350 HydrophobicContact CG2-CD2 4.45Å; V324-L357 HydrophobicContact CG1-CD1 4.47Å; V324-L357 HydrophobicContact CG2-CD1 3.9Å; V324-L357 HydrophobicContact CG2-CD2 3.48Å; V324-L357 VanDerWaalsContact CG2-CD2 3.48Å; V324-L357 HydrophobicContact CG2-CG 4.31Å; V324-L364 HydrophobicContact CG1-CD2 4.42Å; V324-L365 HydrophobicContact CG1-CB 4.16Å
325K94Very high94.6Very high105 Ų10534.5 Ų34.546%0.45717%0.166SC..Hα-helixtrans-60.9-45.1176.4-171.8-175.9176.9-1690112.2C323 S328 D329 L364C323-K325 PolarHBondContact O-N 3.41Å; K325-S328 PolarHBondContact O-N 3.34Å; K325-D329 VanDerWaalsContact O-CB 3.27Å; K325-D329 WeakPolarHBondContact O-CB 3.34Å; K325-D329 PolarHBondContact O-N 3.07Å; K325-L364 HydrophobicContact CB-CD2 3.67Å; K325-L364 HydrophobicContact CG-CD2 4.1Å
326G95.4Very high94.4Very high3 Ų334.1 Ų34.13%0.03116%0.162CC..Hα-helixtrans-63.1-44179.800000112.2C323 V324 D329 L330C323-G326 WeakPolarHBondContact O-CA 3.31Å; C323-G326 PolarHBondContact O-N 3.03Å; C323-G326 PolarHBondContact SG-N 3.15Å; C323-G326 VanDerWaalsContact SG-N 3.4Å; V324-G326 PolarHBondContact O-N 3.33Å; G326-D329 PolarHBondContact O-N 3.23Å; G326-L330 WeakPolarHBondContact O-CB 3.07Å; G326-L330 PolarHBondContact O-N 2.91Å
327R97Very high94.3Very high17 Ų1735.8 Ų35.86%0.06418%0.177CC..Hα-helixtrans-66.8-41.4176.3-71.2170.963.9-171.8-0.1112.2V317 P321 C323 V324 L330 A331 I346 Q349 L350 E353V317-R327 HydrophobicContact CG1-CG 3.76Å; V317-R327 HydrophobicContact CG2-CG 3.95Å; P321-R327 WeakPolarHBondContact O-CD 3.45Å; C323-R327 PolarHBondContact O-N 3.46Å; V324-R327 PolarHBondContact O-N 3.42Å; R327-L330 PolarHBondContact O-N 3.28Å; R327-A331 PolarHBondContact O-N 3.45Å; R327-I346 HydrophobicContact CB-CG2 4.16Å; R327-I346 WeakPolarHBondContact O-CG2 3.22Å; R327-Q349 VanDerWaalsContact NH2-CG 3.33Å; R327-Q349 VanDerWaalsContact NH2-NE2 3.17Å; R327-L350 HydrophobicContact CB-CD1 3.81Å; R327-L350 HydrophobicContact CB-CD2 4.01Å; R327-L350 HydrophobicContact CB-CG 4.22Å; R327-L350 VanDerWaalsContact CZ-CD2 3.45Å; R327-E353 IonicContact CZ-OE1 2.74Å; R327-E353 IonicContact CZ-OE2 2.71Å; R327-E353 IonicContact NH1-OE1 2.78Å; R327-E353 PolarHBondContact NH1-OE1 3.37Å; R327-E353 IonicContact NH1-OE2 2.71Å; R327-E353 PolarHBondContact NH1-OE2 3.44Å; R327-E353 IonicContact NH2-OE1 2.84Å; R327-E353 PolarHBondContact NH2-OE1 3.29Å; R327-E353 IonicContact NH2-OE2 2.67Å; R327-E353 PolarHBondContact NH2-OE2 3.29Å
328S96.8Very high94.2Very high2 Ų240.2 Ų40.21%0.01420%0.195CC..Hα-helixtrans-65.8-38.5176-56.90000112.3V324 K325 S332 Y347V324-S328 VanDerWaalsContact O-CB 3.31Å; V324-S328 WeakPolarHBondContact O-CB 3.43Å; V324-S328 PolarHBondContact O-N 3.07Å; V324-S328 PolarHBondContact O-OG 3.43Å; K325-S328 PolarHBondContact O-N 3.34Å; S328-S332 WeakPolarHBondContact O-CB 3.17Å; S328-S332 PolarHBondContact O-N 3.35Å; S328-S332 PolarHBondContact O-OG 2.8Å; S328-Y347 PolarHBondContact O-OH 3.44Å
329D96.2Very high94.2Very high18 Ų1835.3 Ų35.310%0.09618%0.182CC..Hα-helixtrans-63.9-43.8173.2-77.8-30.8000110.6K289 F313 K325 G326 S332 L333K289-D329 HydrophobicContact CD-CB 3.85Å; K289-D329 VanDerWaalsContact CD-CG 3.48Å; K289-D329 WeakPolarHBondContact CD-OD1 3.48Å; K289-D329 IonicContact NZ-OD1 3.46Å; K289-D329 PolarHBondContact NZ-OD1 3.25Å; K289-D329 IonicContact NZ-OD2 3.14Å; K289-D329 PolarHBondContact NZ-OD2 2.98Å; F313-D329 HydrophobicContact CD1-CB 3.94Å; F313-D329 HydrophobicContact CE1-CB 3.37Å; F313-D329 HydrophobicContact CZ-CB 3.73Å; K325-D329 VanDerWaalsContact O-CB 3.27Å; K325-D329 WeakPolarHBondContact O-CB 3.34Å; K325-D329 PolarHBondContact O-N 3.07Å; G326-D329 PolarHBondContact O-N 3.23Å; D329-S332 WeakPolarHBondContact O-CB 3.25Å; D329-S332 PolarHBondContact O-N 3.48Å; D329-L333 WeakPolarHBondContact O-CG 3.43Å; D329-L333 PolarHBondContact O-N 3.37Å
330L97.7Very high94.3Very high11 Ų1134.5 Ų34.56%0.05818%0.183CC..Hα-helixtrans-61.4-46.1175.4-179.658.8000112.1I310 F313 E314 V317 G326 R327 S332 L333 H334 I346I310-L330 HydrophobicContact CG2-CD1 4.15Å; F313-L330 HydrophobicContact CB-CB 4.21Å; F313-L330 HydrophobicContact CB-CD1 3.89Å; E314-L330 HydrophobicContact CG-CD1 4.06Å; E314-L330 HydrophobicContact CG-CD2 4.24Å; V317-L330 HydrophobicContact CB-CD2 4.39Å; V317-L330 HydrophobicContact CG2-CB 4.42Å; V317-L330 HydrophobicContact CG2-CD2 4.03Å; G326-L330 WeakPolarHBondContact O-CB 3.07Å; G326-L330 PolarHBondContact O-N 2.91Å; R327-L330 PolarHBondContact O-N 3.28Å; L330-S332 VanDerWaalsContact C-N 3.28Å; L330-S332 PolarHBondContact O-N 3.43Å; L330-L333 WeakPolarHBondContact O-CB 3.44Å; L330-L333 PolarHBondContact O-N 2.94Å; L330-L333 VanDerWaalsContact O-N 3.12Å; L330-H334 PolarHBondContact O-CD2 2.78Å; L330-H334 VanDerWaalsContact O-CD2 3.29Å; L330-H334 PolarHBondContact O-N 3.22Å; L330-I346 HydrophobicContact CD2-CD1 4.14Å; L330-I346 HydrophobicContact CG-CD1 3.99Å
331A97.3Very high94.4Very high0 Ų040.1 Ų40.10%021%0.21CC..Hα-helixtrans-59.6-40.8174.900000111.8R327 L333 H334 R335 A343 I346 Y347R327-A331 PolarHBondContact O-N 3.45Å; A331-L333 VanDerWaalsContact C-N 3.31Å; A331-L333 PolarHBondContact O-N 3.44Å; A331-H334 PolarHBondContact O-N 2.94Å; A331-R335 PolarHBondContact O-N 3.36Å; A331-R335 VanDerWaalsContact O-N 3.07Å; A331-A343 VanDerWaalsContact O-CB 3.25Å; A331-A343 WeakPolarHBondContact O-CB 3.35Å; A331-I346 HydrophobicContact CB-CB 3.97Å; A331-I346 HydrophobicContact CB-CD1 4.35Å; A331-I346 HydrophobicContact CB-CG2 3.86Å; A331-Y347 HydrophobicContact CB-CD2 3.82Å; A331-Y347 HydrophobicContact CB-CE1 4.26Å; A331-Y347 HydrophobicContact CB-CE2 3.46Å; A331-Y347 VanDerWaalsContact CB-CE2 3.46Å; A331-Y347 HydrophobicContact CB-CG 4.34Å
332S94.7Very high94.6Very high22 Ų2242.9 Ų42.915%0.15421%0.214CC..Hα-helixtrans-63.1-37175.6-62.30000112.4S328 D329 L330 R335 Y336 Y347S328-S332 WeakPolarHBondContact O-CB 3.17Å; S328-S332 PolarHBondContact O-N 3.35Å; S328-S332 PolarHBondContact O-OG 2.8Å; D329-S332 WeakPolarHBondContact O-CB 3.25Å; D329-S332 PolarHBondContact O-N 3.48Å; L330-S332 VanDerWaalsContact C-N 3.28Å; L330-S332 PolarHBondContact O-N 3.43Å; S332-R335 WeakPolarHBondContact O-CB 3.41Å; S332-R335 PolarHBondContact O-N 2.97Å; S332-Y336 WeakPolarHBondContact O-CD2 3.42Å; S332-Y336 PolarHBondContact O-N 3.48Å; S332-Y347 PolarHBondContact OG-OH 3.22Å
333L96.2Very high94.8Very high0 Ų041.9 Ų41.90%021%0.208CC..Hα-helixtrans-69.3-41.1175.6-70.1165.8000112.2K289 V292 F293 S309 I310 F313 D329 L330 A331 R335 Y336 A337K289-L333 HydrophobicContact CG-CD2 4.38Å; V292-L333 HydrophobicContact CB-CD2 4.49Å; V292-L333 HydrophobicContact CG1-CD2 4.28Å; F293-L333 HydrophobicContact CE1-CD2 4.22Å; S309-L333 WeakPolarHBondContact OG-CD1 3.47Å; S309-L333 WeakPolarHBondContact OG-CD2 3.3Å; I310-L333 HydrophobicContact CD1-CB 4.47Å; I310-L333 HydrophobicContact CG1-CB 3.73Å; F313-L333 HydrophobicContact CB-CD1 4.11Å; F313-L333 HydrophobicContact CD2-CD1 3.4Å; F313-L333 VanDerWaalsContact CD2-CD1 3.4Å; F313-L333 HydrophobicContact CE2-CD1 4Å; F313-L333 HydrophobicContact CG-CD1 3.88Å; D329-L333 WeakPolarHBondContact O-CG 3.43Å; D329-L333 PolarHBondContact O-N 3.37Å; L330-L333 WeakPolarHBondContact O-CB 3.44Å; L330-L333 PolarHBondContact O-N 2.94Å; L330-L333 VanDerWaalsContact O-N 3.12Å; A331-L333 VanDerWaalsContact C-N 3.31Å; A331-L333 PolarHBondContact O-N 3.44Å; L333-R335 VanDerWaalsContact C-N 3.27Å; L333-R335 PolarHBondContact O-N 2.71Å; L333-Y336 CarbonylContact O-C 3.38Å; L333-Y336 WeakPolarHBondContact O-CA 3.45Å; L333-Y336 WeakPolarHBondContact O-CB 3.34Å; L333-Y336 PolarHBondContact O-N 2.87Å; L333-A337 PolarHBondContact O-N 3.25Å
334H96.5Very high95Very high12 Ų1241.4 Ų41.46%0.05620%0.201CC..Hα-helixtrans-59.9-37.5173-78.1-65.4000112.2L330 A331 Y336 A337 H338 N339 R342 A343L330-H334 PolarHBondContact O-CD2 2.78Å; L330-H334 VanDerWaalsContact O-CD2 3.29Å; L330-H334 PolarHBondContact O-N 3.22Å; A331-H334 PolarHBondContact O-N 2.94Å; H334-Y336 VanDerWaalsContact C-N 3.33Å; H334-Y336 PolarHBondContact O-N 3.07Å; H334-A337 CarbonylContact O-C 3.57Å; H334-A337 WeakPolarHBondContact O-CA 3.41Å; H334-A337 WeakPolarHBondContact O-CB 3.36Å; H334-A337 PolarHBondContact O-N 2.72Å; H334-A337 VanDerWaalsContact O-N 3.08Å; H334-H338 PolarHBondContact O-N 2.86Å; H334-N339 HydrophobicContact CB-CB 4.35Å; H334-N339 PolarHBondContact O-N 3Å; H334-R342 HydrophobicContact CB-CB 4.47Å; H334-A343 HydrophobicContact CB-CB 3.99Å
335R93.1Very high95.2Very high44 Ų4445.2 Ų45.217%0.16622%0.219CC..Hα-helixtrans-58.7-43.4170.5-176.3-168.761.786.3-3.8111.8A331 S332 L333 A337 H338 A343 Y372 T376A331-R335 PolarHBondContact O-N 3.36Å; A331-R335 VanDerWaalsContact O-N 3.07Å; S332-R335 WeakPolarHBondContact O-CB 3.41Å; S332-R335 PolarHBondContact O-N 2.97Å; L333-R335 VanDerWaalsContact C-N 3.27Å; L333-R335 PolarHBondContact O-N 2.71Å; R335-A337 PolarHBondContact O-N 2.9Å; R335-H338 PolarHBondContact O-N 3.14Å; R335-A343 HydrophobicContact CB-CB 4.49Å; R335-Y372 HydrophobicContact CB-CD2 4.09Å; R335-Y372 HydrophobicContact CB-CE2 4.11Å; R335-Y372 HydrophobicContact CG-CD2 4.15Å; R335-Y372 HydrophobicContact CG-CE2 4.19Å; R335-T376 HydrophobicContact CG-CG2 4.23Å
336Y91.5Very high95.4Very high48 Ų4840.6 Ų40.619%0.18820%0.199CC..Hα-helixtrans-67.6-23.3175.9-80-69.8000113.5V292 F293 R302 S332 L333 H334 H338V292-Y336 HydrophobicContact CG1-CD2 4.28Å; V292-Y336 HydrophobicContact CG1-CG 4.19Å; F293-Y336 HydrophobicContact CD1-CD2 4.02Å; F293-Y336 AromaticContact CD1-CE2 3.37Å; F293-Y336 HydrophobicContact CD1-CE2 3.37Å; F293-Y336 AromaticContact CD1-CZ 3.99Å; F293-Y336 AromaticContact CE1-CD2 3.68Å; F293-Y336 HydrophobicContact CE1-CD2 3.68Å; F293-Y336 AromaticContact CE1-CE2 3.27Å; F293-Y336 HydrophobicContact CE1-CE2 3.27Å; F293-Y336 HydrophobicContact CG-CE2 4.39Å; F293-Y336 HydrophobicContact CZ-CE2 4.2Å; R302-Y336 VanDerWaalsContact CZ-CE1 3.49Å; S332-Y336 WeakPolarHBondContact O-CD2 3.42Å; S332-Y336 PolarHBondContact O-N 3.48Å; L333-Y336 CarbonylContact O-C 3.38Å; L333-Y336 WeakPolarHBondContact O-CA 3.45Å; L333-Y336 WeakPolarHBondContact O-CB 3.34Å; L333-Y336 PolarHBondContact O-N 2.87Å; H334-Y336 VanDerWaalsContact C-N 3.33Å; H334-Y336 PolarHBondContact O-N 3.07Å; Y336-H338 PolarHBondContact O-N 2.81Å
337A93.3Very high95.5Very high43 Ų4340.5 Ų40.536%0.35520%0.198SC..THydrogen-bonded Turntrans-82.14.5171.100000113.2V306 I310 L333 H334 R335 N339V306-A337 HydrophobicContact CG1-CB 3.68Å; I310-A337 HydrophobicContact CD1-CB 3.79Å; L333-A337 PolarHBondContact O-N 3.25Å; H334-A337 CarbonylContact O-C 3.57Å; H334-A337 WeakPolarHBondContact O-CA 3.41Å; H334-A337 WeakPolarHBondContact O-CB 3.36Å; H334-A337 PolarHBondContact O-N 2.72Å; H334-A337 VanDerWaalsContact O-N 3.08Å; R335-A337 PolarHBondContact O-N 2.9Å; A337-N339 PolarHBondContact O-N 3.15Å
338H91.3Very high95.5Very high119 Ų11943.7 Ų43.755%0.55121%0.213SC*.THydrogen-bonded Turntrans60.119.8-171.8-54.3-70.5000114.1D298 H334 R335 Y336 T340D298-H338 IonicContact OD2-CE1 3.31Å; D298-H338 IonicContact OD2-NE2 3.54Å; D298-H338 PolarHBondContact OD2-NE2 3.26Å; H334-H338 PolarHBondContact O-N 2.86Å; R335-H338 PolarHBondContact O-N 3.14Å; Y336-H338 PolarHBondContact O-N 2.81Å; H338-T340 PolarHBondContact O-N 3.25Å
339N94.1Very high95.5Very high66 Ų6648.3 Ų48.335%0.35324%0.235SC..  trans-94.674.5173.1-170.2-15.4000109.6H334 A337 R342 A343H334-N339 HydrophobicContact CB-CB 4.35Å; H334-N339 PolarHBondContact O-N 3Å; A337-N339 PolarHBondContact O-N 3.15Å; N339-R342 HydrophobicContact CB-CB 4.5Å; N339-R342 VanDerWaalsContact CG-CB 3.47Å; N339-R342 WeakPolarHBondContact ND2-CB 3.35Å; N339-R342 WeakPolarHBondContact OD1-CB 3.33Å; N339-R342 PolarHBondContact OD1-N 3.27Å; N339-A343 PolarHBondContact O-N 3.42Å
340T92.6Very high95.6Very high67 Ų6747.5 Ų47.541%0.41123%0.231SC..Hα-helixtrans-68.6-34-176.749.40000112.8H338 A343 E344 Y372 T376H338-T340 PolarHBondContact O-N 3.25Å; T340-A343 PolarHBondContact O-N 3.5Å; T340-E344 WeakPolarHBondContact O-CB 3.4Å; T340-E344 PolarHBondContact O-N 3.29Å; T340-Y372 PolarHBondContact O-OH 2.94Å; T340-T376 HydrophobicContact CG2-CG2 4.06Å
341E94.4Very high95.5Very high140 Ų14048.2 Ų48.265%0.65423%0.234SC*.Hα-helixtrans-58.8-55.6176.3-178.4176-160.800110.5A343 E344 E345E341-A343 VanDerWaalsContact C-N 3.29Å; E341-A343 PolarHBondContact O-N 3.5Å; E341-E344 PolarHBondContact O-N 3.14Å; E341-E344 VanDerWaalsContact O-N 3.09Å; E341-E345 WeakPolarHBondContact O-CG 3.34Å; E341-E345 PolarHBondContact O-N 2.71Å
342R96.6Very high95.5Very high110 Ų11052 Ų5242%0.41526%0.26SS..Hα-helixtrans-62.3-37.3179.5-174.155.2175170.11.2112.9H334 N339 E345 I346H334-R342 HydrophobicContact CB-CB 4.47Å; N339-R342 HydrophobicContact CB-CB 4.5Å; N339-R342 VanDerWaalsContact CG-CB 3.47Å; N339-R342 WeakPolarHBondContact ND2-CB 3.35Å; N339-R342 WeakPolarHBondContact OD1-CB 3.33Å; N339-R342 PolarHBondContact OD1-N 3.27Å; R342-E345 WeakPolarHBondContact CD-OE2 3.22Å; R342-E345 IonicContact CZ-OE2 3.39Å; R342-E345 IonicContact NE-OE2 2.66Å; R342-E345 IonicContact NH1-OE2 3.13Å; R342-E345 PolarHBondContact NH1-OE2 3.4Å; R342-I346 HydrophobicContact CG-CD1 4.32Å; R342-I346 WeakPolarHBondContact O-CG1 3.32Å; R342-I346 PolarHBondContact O-N 2.91Å
343A96.6Very high95.5Very high0 Ų053.2 Ų53.20%026%0.264CS..Hα-helixtrans-63.5-43.1175.600000111.8A331 H334 R335 N339 T340 E341 I346 Y347 Y372A331-A343 VanDerWaalsContact O-CB 3.25Å; A331-A343 WeakPolarHBondContact O-CB 3.35Å; H334-A343 HydrophobicContact CB-CB 3.99Å; R335-A343 HydrophobicContact CB-CB 4.49Å; N339-A343 PolarHBondContact O-N 3.42Å; T340-A343 PolarHBondContact O-N 3.5Å; E341-A343 VanDerWaalsContact C-N 3.29Å; E341-A343 PolarHBondContact O-N 3.5Å; A343-I346 PolarHBondContact O-N 3.11Å; A343-Y347 WeakPolarHBondContact O-CD2 3.37Å; A343-Y347 PolarHBondContact O-N 3.42Å; A343-Y372 HydrophobicContact CB-CD2 4.18Å; A343-Y372 HydrophobicContact CB-CE2 3.43Å; A343-Y372 VanDerWaalsContact CB-CE2 3.43Å
344E96Very high95.5Very high37 Ų3755.2 Ų55.217%0.17327%0.274CS..Hα-helixtrans-64.8-44.7177.4-174.764.9-170.600110.9T340 E341 I346 Y347 Q348 Y369 Y372 K382T340-E344 WeakPolarHBondContact O-CB 3.4Å; T340-E344 PolarHBondContact O-N 3.29Å; E341-E344 PolarHBondContact O-N 3.14Å; E341-E344 VanDerWaalsContact O-N 3.09Å; E344-I346 VanDerWaalsContact C-N 3.33Å; E344-I346 PolarHBondContact O-N 2.67Å; E344-Y347 PolarHBondContact O-N 3.21Å; E344-Y347 VanDerWaalsContact O-N 3.15Å; E344-Q348 HydrophobicContact CG-CG 4.18Å; E344-Q348 WeakPolarHBondContact O-CG 3.34Å; E344-Q348 PolarHBondContact O-N 3.16Å; E344-Q348 PolarHBondContact OE1-NE2 2.93Å; E344-Y369 PolarHBondContact OE1-OH 2.86Å; E344-Y369 WeakPolarHBondContact OE2-CE2 3.39Å; E344-Y369 PolarHBondContact OE2-OH 2.98Å; E344-Y372 WeakPolarHBondContact OE2-CE1 3.2Å; E344-K382 IonicContact OE1-NZ 3.92Å
345E97.4Very high95.3Very high86 Ų8661.2 Ų61.240%0.40230%0.302SS..Hα-helixtrans-53-48.6175.9-72.6175.1175.700112.3E341 R342 Y347 Q348 Q349E341-E345 WeakPolarHBondContact O-CG 3.34Å; E341-E345 PolarHBondContact O-N 2.71Å; R342-E345 WeakPolarHBondContact CD-OE2 3.22Å; R342-E345 IonicContact CZ-OE2 3.39Å; R342-E345 IonicContact NE-OE2 2.66Å; R342-E345 IonicContact NH1-OE2 3.13Å; R342-E345 PolarHBondContact NH1-OE2 3.4Å; E345-Y347 VanDerWaalsContact C-N 3.34Å; E345-Y347 PolarHBondContact O-N 2.93Å; E345-Q348 PolarHBondContact O-N 3.28Å; E345-Q349 WeakPolarHBondContact O-CB 3.33Å; E345-Q349 PolarHBondContact O-N 2.65Å
346I98.1Very high95.3Very high8 Ų860.4 Ų60.44%0.04130%0.302CS..Hα-helixtrans-63-42.6-179.9-65.8165.8000110.7R327 L330 A331 R342 A343 E344 Q349 L350R327-I346 HydrophobicContact CB-CG2 4.16Å; R327-I346 WeakPolarHBondContact O-CG2 3.22Å; L330-I346 HydrophobicContact CD2-CD1 4.14Å; L330-I346 HydrophobicContact CG-CD1 3.99Å; A331-I346 HydrophobicContact CB-CB 3.97Å; A331-I346 HydrophobicContact CB-CD1 4.35Å; A331-I346 HydrophobicContact CB-CG2 3.86Å; R342-I346 HydrophobicContact CG-CD1 4.32Å; R342-I346 WeakPolarHBondContact O-CG1 3.32Å; R342-I346 PolarHBondContact O-N 2.91Å; A343-I346 PolarHBondContact O-N 3.11Å; E344-I346 VanDerWaalsContact C-N 3.33Å; E344-I346 PolarHBondContact O-N 2.67Å; I346-Q349 PolarHBondContact O-N 3.08Å; I346-L350 HydrophobicContact CG2-CD1 4.21Å; I346-L350 WeakPolarHBondContact O-CG 3.42Å; I346-L350 PolarHBondContact O-N 3.37Å
347Y97.6Very high95.5Very high1 Ų158.1 Ų58.10%0.00429%0.293CS..Hα-helixtrans-67.1-41.5177.7-79.8-58.6000112.4S328 A331 S332 A343 E344 E345 Q349 L350 L351 L365 S368 Y369 Y372S328-Y347 PolarHBondContact O-OH 3.44Å; A331-Y347 HydrophobicContact CB-CD2 3.82Å; A331-Y347 HydrophobicContact CB-CE1 4.26Å; A331-Y347 HydrophobicContact CB-CE2 3.46Å; A331-Y347 VanDerWaalsContact CB-CE2 3.46Å; A331-Y347 HydrophobicContact CB-CG 4.34Å; S332-Y347 PolarHBondContact OG-OH 3.22Å; A343-Y347 WeakPolarHBondContact O-CD2 3.37Å; A343-Y347 PolarHBondContact O-N 3.42Å; E344-Y347 PolarHBondContact O-N 3.21Å; E344-Y347 VanDerWaalsContact O-N 3.15Å; E345-Y347 VanDerWaalsContact C-N 3.34Å; E345-Y347 PolarHBondContact O-N 2.93Å; Y347-Q349 VanDerWaalsContact C-N 3.3Å; Y347-Q349 PolarHBondContact O-N 3.02Å; Y347-L350 HydrophobicContact CD1-CD1 4.43Å; Y347-L350 PolarHBondContact O-N 3.19Å; Y347-L351 WeakPolarHBondContact O-CB 3.43Å; Y347-L351 VanDerWaalsContact O-CG 3.24Å; Y347-L351 WeakPolarHBondContact O-CG 3.32Å; Y347-L351 PolarHBondContact O-N 3.3Å; Y347-L365 HydrophobicContact CD1-CD1 4.13Å; Y347-S368 PolarHBondContact OH-O 3.03Å; Y347-Y369 VanDerWaalsContact CB-CD2 3.47Å; Y347-Y369 AromaticContact CD1-CD2 3.86Å; Y347-Y369 HydrophobicContact CD1-CD2 3.86Å; Y347-Y369 HydrophobicContact CD1-CG 4.36Å; Y347-Y369 AromaticContact CD2-CD2 3.72Å; Y347-Y369 HydrophobicContact CD2-CD2 3.72Å; Y347-Y369 HydrophobicContact CD2-CE2 4.2Å; Y347-Y369 HydrophobicContact CE2-CD2 4.41Å; Y347-Y369 AromaticContact CG-CD2 3.42Å; Y347-Y369 HydrophobicContact CG-CD2 3.42Å; Y347-Y369 VanDerWaalsContact CG-CD2 3.42Å; Y347-Y369 HydrophobicContact CG-CE2 4.02Å; Y347-Y369 HydrophobicContact CG-CG 4.33Å; Y347-Y372 HydrophobicContact CD2-CD1 4.02Å; Y347-Y372 HydrophobicContact CD2-CD2 4.18Å; Y347-Y372 AromaticContact CD2-CG 3.84Å; Y347-Y372 HydrophobicContact CD2-CG 3.84Å; Y347-Y372 VanDerWaalsContact CE2-CB 3.49Å; Y347-Y372 HydrophobicContact CE2-CD1 4.15Å; Y347-Y372 AromaticContact CE2-CD2 3.72Å; Y347-Y372 HydrophobicContact CE2-CD2 3.72Å; Y347-Y372 AromaticContact CE2-CG 3.5Å; Y347-Y372 HydrophobicContact CE2-CG 3.5Å; Y347-Y372 VanDerWaalsContact CE2-CG 3.5Å
348Q97.3Very high95.5Very high84 Ų8456.1 Ų56.139%0.39328%0.277SS..Hα-helixtrans-61.9-40.4176.1-69.3-53.1-35.300111.7E344 E345 L351 S352 Y369E344-Q348 HydrophobicContact CG-CG 4.18Å; E344-Q348 WeakPolarHBondContact O-CG 3.34Å; E344-Q348 PolarHBondContact O-N 3.16Å; E344-Q348 PolarHBondContact OE1-NE2 2.93Å; E345-Q348 PolarHBondContact O-N 3.28Å; Q348-L351 PolarHBondContact O-N 2.72Å; Q348-S352 PolarHBondContact O-N 2.77Å; Q348-Y369 PolarHBondContact NE2-OH 3.08Å
349Q97.2Very high95.7Very high99 Ų9951.3 Ų51.346%0.46326%0.256SS..Hα-helixtrans-63.8-41.5174.1-162.8-163-14.200112.1R327 E345 I346 Y347 L351 S352 E353R327-Q349 VanDerWaalsContact NH2-CG 3.33Å; R327-Q349 VanDerWaalsContact NH2-NE2 3.17Å; E345-Q349 WeakPolarHBondContact O-CB 3.33Å; E345-Q349 PolarHBondContact O-N 2.65Å; I346-Q349 PolarHBondContact O-N 3.08Å; Y347-Q349 VanDerWaalsContact C-N 3.3Å; Y347-Q349 PolarHBondContact O-N 3.02Å; Q349-L351 VanDerWaalsContact C-N 3.33Å; Q349-L351 PolarHBondContact O-N 3.09Å; Q349-S352 PolarHBondContact O-N 3.41Å; Q349-S352 PolarHBondContact O-OG 3.34Å; Q349-E353 WeakPolarHBondContact CG-OE1 3.38Å; Q349-E353 PolarHBondContact NE2-OE1 3.08Å; Q349-E353 VanDerWaalsContact NE2-OE1 3.11Å; Q349-E353 WeakPolarHBondContact O-CG 3.44Å; Q349-E353 PolarHBondContact O-N 3.05Å
350L97.3Very high95.6Very high1 Ų150.5 Ų50.51%0.00525%0.25CC..Hα-helixtrans-65.7-36.8175.8-76.2168.5000112.4V324 R327 I346 Y347 E353 D354 L365V324-L350 HydrophobicContact CG1-CD2 4.34Å; V324-L350 HydrophobicContact CG2-CD2 4.45Å; R327-L350 HydrophobicContact CB-CD1 3.81Å; R327-L350 HydrophobicContact CB-CD2 4.01Å; R327-L350 HydrophobicContact CB-CG 4.22Å; R327-L350 VanDerWaalsContact CZ-CD2 3.45Å; I346-L350 HydrophobicContact CG2-CD1 4.21Å; I346-L350 WeakPolarHBondContact O-CG 3.42Å; I346-L350 PolarHBondContact O-N 3.37Å; Y347-L350 HydrophobicContact CD1-CD1 4.43Å; Y347-L350 PolarHBondContact O-N 3.19Å; L350-E353 PolarHBondContact O-N 3.4Å; L350-D354 PolarHBondContact O-N 2.97Å; L350-L365 HydrophobicContact CB-CD1 3.51Å; L350-L365 HydrophobicContact CB-CD2 3.99Å; L350-L365 HydrophobicContact CB-CG 4.4Å; L350-L365 HydrophobicContact CD1-CD1 3.94Å; L350-L365 HydrophobicContact CG-CD1 4.33Å; L350-L365 WeakPolarHBondContact O-CD2 3.48Å
351L97.3Very high95.7Very high25 Ų2548.1 Ų48.113%0.13124%0.236CC..Hα-helixtrans-69.9-34.1179.3-72.9168.6000112.5Y347 Q348 Q349 E353 D354 L365 Y366 Y369 F386Y347-L351 WeakPolarHBondContact O-CB 3.43Å; Y347-L351 VanDerWaalsContact O-CG 3.24Å; Y347-L351 WeakPolarHBondContact O-CG 3.32Å; Y347-L351 PolarHBondContact O-N 3.3Å; Q348-L351 PolarHBondContact O-N 2.72Å; Q349-L351 VanDerWaalsContact C-N 3.33Å; Q349-L351 PolarHBondContact O-N 3.09Å; L351-E353 PolarHBondContact O-N 3.45Å; L351-D354 WeakPolarHBondContact O-CB 3.4Å; L351-D354 VanDerWaalsContact O-CG 3.26Å; L351-D354 PolarHBondContact O-N 2.96Å; L351-L365 HydrophobicContact CD2-CD1 4.49Å; L351-L365 HydrophobicContact CD2-CD2 4.02Å; L351-L365 HydrophobicContact CD2-CG 4.11Å; L351-L365 HydrophobicContact CG-CD2 4.47Å; L351-Y366 HydrophobicContact CD2-CD1 3.99Å; L351-Y366 HydrophobicContact CD2-CE1 3.89Å; L351-Y369 HydrophobicContact CD1-CD1 3.79Å; L351-Y369 HydrophobicContact CD1-CE1 3.68Å; L351-Y369 HydrophobicContact CD1-CG 4.27Å; L351-F386 HydrophobicContact CD1-CE1 4.39Å; L351-F386 HydrophobicContact CD1-CZ 4.12Å; L351-F386 HydrophobicContact CD2-CE1 3.61Å; L351-F386 HydrophobicContact CD2-CZ 4.14Å
352S96.7Very high95.8Very high79 Ų7943.4 Ų43.455%0.55221%0.214SC*.Hα-helixtrans-69.9-23.3174.464.80000113Q348 Q349 H355Q348-S352 PolarHBondContact O-N 2.77Å; Q349-S352 PolarHBondContact O-N 3.41Å; Q349-S352 PolarHBondContact O-OG 3.34Å; S352-H355 PolarHBondContact O-CE1 3.06Å; S352-H355 PolarHBondContact O-ND1 3.25Å
353E95.2Very high95.8Very high48 Ų4838.1 Ų38.122%0.22419%0.194CC..THydrogen-bonded Turntrans-91.81.3178.2-64.4167.9-151.900113.1R327 Q349 L350 L351 H355 T356R327-E353 IonicContact CZ-OE1 2.74Å; R327-E353 IonicContact CZ-OE2 2.71Å; R327-E353 IonicContact NH1-OE1 2.78Å; R327-E353 PolarHBondContact NH1-OE1 3.37Å; R327-E353 IonicContact NH1-OE2 2.71Å; R327-E353 PolarHBondContact NH1-OE2 3.44Å; R327-E353 IonicContact NH2-OE1 2.84Å; R327-E353 PolarHBondContact NH2-OE1 3.29Å; R327-E353 IonicContact NH2-OE2 2.67Å; R327-E353 PolarHBondContact NH2-OE2 3.29Å; Q349-E353 WeakPolarHBondContact CG-OE1 3.38Å; Q349-E353 PolarHBondContact NE2-OE1 3.08Å; Q349-E353 VanDerWaalsContact NE2-OE1 3.11Å; Q349-E353 WeakPolarHBondContact O-CG 3.44Å; Q349-E353 PolarHBondContact O-N 3.05Å; L350-E353 PolarHBondContact O-N 3.4Å; L351-E353 PolarHBondContact O-N 3.45Å; E353-H355 VanDerWaalsContact C-N 3.3Å; E353-H355 PolarHBondContact O-N 2.8Å; E353-T356 WeakPolarHBondContact O-CB 3.47Å; E353-T356 PolarHBondContact O-N 3.26Å; E353-T356 PolarHBondContact O-OG1 3.14Å
354D94.8Very high95.8Very high42 Ų4239.6 Ų39.623%0.22520%0.202CC..G310 helixtrans-61.8-31.9-166.276.4-15000114.9L350 L351 T356 L357 Q362 L365 Y366L350-D354 PolarHBondContact O-N 2.97Å; L351-D354 WeakPolarHBondContact O-CB 3.4Å; L351-D354 VanDerWaalsContact O-CG 3.26Å; L351-D354 PolarHBondContact O-N 2.96Å; D354-T356 PolarHBondContact O-N 3Å; D354-L357 HydrophobicContact CB-CD1 4.49Å; D354-L357 VanDerWaalsContact O-CB 3.32Å; D354-L357 WeakPolarHBondContact O-CB 3.4Å; D354-L357 PolarHBondContact O-N 3.12Å; D354-Q362 PolarHBondContact O-NE2 3.29Å; D354-L365 HydrophobicContact CB-CD2 4.22Å; D354-Y366 PolarHBondContact OD2-OH 3.02Å
355H93.1Very high95.9Very high139 Ų13937.9 Ų37.964%0.64419%0.194SC*.G310 helixtrans-61.8-21.117666.2-79.7000113.5S352 E353S352-H355 PolarHBondContact O-CE1 3.06Å; S352-H355 PolarHBondContact O-ND1 3.25Å; E353-H355 VanDerWaalsContact C-N 3.3Å; E353-H355 PolarHBondContact O-N 2.8Å
356T93.8Very high95.9Very high26 Ų2634.8 Ų34.816%0.1618%0.178CC..G310 helixtrans-87.2-10.1177.3720000113.2N25 E353 D354N25-T356 PolarHBondContact N-O 2.97Å; E353-T356 WeakPolarHBondContact O-CB 3.47Å; E353-T356 PolarHBondContact O-N 3.26Å; E353-T356 PolarHBondContact O-OG1 3.14Å; D354-T356 PolarHBondContact O-N 3Å
357L95Very high95.9Very high1 Ų136.7 Ų36.71%0.00519%0.185CC..SBendtrans-90.5143.7-169.6-56.5-175.8000111.4Y23 N25 V324 D354 Q362 L365Y23-L357 WeakPolarHBondContact CD1-O 3.41Å; N25-L357 HydrophobicContact CB-CD2 3.63Å; V324-L357 HydrophobicContact CG1-CD1 4.47Å; V324-L357 HydrophobicContact CG2-CD1 3.9Å; V324-L357 HydrophobicContact CG2-CD2 3.48Å; V324-L357 VanDerWaalsContact CG2-CD2 3.48Å; V324-L357 HydrophobicContact CG2-CG 4.31Å; D354-L357 HydrophobicContact CB-CD1 4.49Å; D354-L357 VanDerWaalsContact O-CB 3.32Å; D354-L357 WeakPolarHBondContact O-CB 3.4Å; D354-L357 PolarHBondContact O-N 3.12Å; L357-Q362 HydrophobicContact CB-CG 3.72Å; L357-Q362 PolarHBondContact O-NE2 3.27Å; L357-L365 HydrophobicContact CD1-CD2 3.9Å
358P93.9Very high95.8Very high1 Ų137.4 Ų37.41%0.00619%0.191CC..  trans-66.2154.9168.930.1-36.5000110.9Y23 E26 H360 S361 Q362Y23-P358 HydrophobicContact CD1-CB 4.25Å; Y23-P358 HydrophobicContact CD2-CB 3.49Å; Y23-P358 VanDerWaalsContact CD2-CB 3.49Å; Y23-P358 HydrophobicContact CE2-CB 3.91Å; Y23-P358 HydrophobicContact CG-CB 3.69Å; E26-P358 HydrophobicContact CB-CG 4.12Å; P358-H360 VanDerWaalsContact C-N 3.26Å; P358-H360 WeakPolarHBondContact CG-CE1 3.37Å; P358-H360 PolarHBondContact O-N 3.48Å; P358-S361 WeakPolarHBondContact O-CA 3.24Å; P358-S361 WeakPolarHBondContact O-CB 3.32Å; P358-S361 PolarHBondContact O-N 3.39Å; P358-Q362 PolarHBondContact O-N 3.01Å
359P93.9Very high95.8Very high17 Ų1733.5 Ų33.511%0.1117%0.172CC..Hα-helixtrans-48.5-42.4-176.9-33.634.9000114.7Y23 S361 Q362 Q363 I393 N395Y23-P359 VanDerWaalsContact OH-CD 3.25Å; Y23-P359 WeakPolarHBondContact OH-CD 3.38Å; P359-S361 VanDerWaalsContact C-N 3.33Å; P359-S361 PolarHBondContact O-N 3.42Å; P359-Q362 PolarHBondContact O-N 2.89Å; P359-Q363 VanDerWaalsContact O-CG 3.29Å; P359-Q363 WeakPolarHBondContact O-CG 3.19Å; P359-Q363 PolarHBondContact O-N 3.03Å; P359-I393 HydrophobicContact CB-CG2 3.63Å; P359-N395 HydrophobicContact CB-CB 4Å; P359-N395 WeakPolarHBondContact CB-OD1 3.45Å; P359-N395 WeakPolarHBondContact CG-OD1 3.49Å
360H92.3Very high95.8Very high50 Ų5028.8 Ų28.823%0.23115%0.15CC..Hα-helixtrans-69.1-28.5-179.868.4-85.9000113.6E26 P358 L364E26-H360 IonicContact OE1-CE1 2.8Å; E26-H360 PolarHBondContact OE1-CE1 3.23Å; E26-H360 VanDerWaalsContact OE1-CE1 3.3Å; E26-H360 IonicContact OE1-NE2 2.88Å; P358-H360 VanDerWaalsContact C-N 3.26Å; P358-H360 WeakPolarHBondContact CG-CE1 3.37Å; P358-H360 PolarHBondContact O-N 3.48Å; H360-L364 PolarHBondContact O-N 2.77Å
361S95Very high95.6Very high17 Ų1730.2 Ų30.212%0.11916%0.16CC..Hα-helixtrans-78.9-35.5174-710000111.5P358 P359 L364 L365P358-S361 WeakPolarHBondContact O-CA 3.24Å; P358-S361 WeakPolarHBondContact O-CB 3.32Å; P358-S361 PolarHBondContact O-N 3.39Å; P359-S361 VanDerWaalsContact C-N 3.33Å; P359-S361 PolarHBondContact O-N 3.42Å; S361-L364 WeakPolarHBondContact O-CB 3.49Å; S361-L364 PolarHBondContact O-N 3.45Å; S361-L365 WeakPolarHBondContact O-CB 3.48Å; S361-L365 PolarHBondContact O-N 3.49Å
362Q96.8Very high95.4Very high40 Ų4029.2 Ų29.219%0.18716%0.155CC..Hα-helixtrans-61.2-46.8170.7-66.1177.3-26.200110.9D354 L357 P358 P359 L364 L365 Y366 I393D354-Q362 PolarHBondContact O-NE2 3.29Å; L357-Q362 HydrophobicContact CB-CG 3.72Å; L357-Q362 PolarHBondContact O-NE2 3.27Å; P358-Q362 PolarHBondContact O-N 3.01Å; P359-Q362 PolarHBondContact O-N 2.89Å; Q362-L364 VanDerWaalsContact C-N 3.3Å; Q362-L364 PolarHBondContact O-N 3.36Å; Q362-L365 PolarHBondContact O-N 3.28Å; Q362-Y366 HydrophobicContact CB-CE2 4.15Å; Q362-Y366 WeakPolarHBondContact O-CB 3.19Å; Q362-Y366 WeakPolarHBondContact O-CD2 3.47Å; Q362-Y366 VanDerWaalsContact O-CG 3.26Å; Q362-Y366 PolarHBondContact O-N 3.45Å; Q362-I393 HydrophobicContact CB-CD1 3.7Å
363Q96.6Very high95.3Very high0 Ų025.5 Ų25.50%013%0.129CC..Hα-helixtrans-57.4-42.1174.7-72.2174.1-26.900112.4P359 Y367 A390 I393 N395 S397 N399P359-Q363 VanDerWaalsContact O-CG 3.29Å; P359-Q363 WeakPolarHBondContact O-CG 3.19Å; P359-Q363 PolarHBondContact O-N 3.03Å; Q363-Y367 WeakPolarHBondContact O-CB 3.41Å; Q363-Y367 PolarHBondContact O-N 3.21Å; Q363-A390 WeakPolarHBondContact CG-O 3.45Å; Q363-A390 PolarHBondContact NE2-O 3.49Å; Q363-I393 HydrophobicContact CG-CB 3.79Å; Q363-I393 HydrophobicContact CG-CD1 3.69Å; Q363-I393 HydrophobicContact CG-CG1 4.33Å; Q363-I393 HydrophobicContact CG-CG2 3.9Å; Q363-I393 PolarHBondContact NE2-O 2.96Å; Q363-N395 PolarHBondContact NE2-O 3.18Å; Q363-N395 PolarHBondContact OE1-O 3.18Å; Q363-S397 PolarHBondContact OE1-OG 2.9Å; Q363-N399 HydrophobicContact CB-CB 4.3Å
364L96.4Very high95.1Very high31 Ų3128.5 Ų28.516%0.16214%0.142CC..Hα-helixtrans-61.3-50.1174.6176.466.4000111.4V324 K325 H360 S361 Q362 Y367 S368 N399V324-L364 HydrophobicContact CG1-CD2 4.42Å; K325-L364 HydrophobicContact CB-CD2 3.67Å; K325-L364 HydrophobicContact CG-CD2 4.1Å; H360-L364 PolarHBondContact O-N 2.77Å; S361-L364 WeakPolarHBondContact O-CB 3.49Å; S361-L364 PolarHBondContact O-N 3.45Å; Q362-L364 VanDerWaalsContact C-N 3.3Å; Q362-L364 PolarHBondContact O-N 3.36Å; L364-Y367 PolarHBondContact O-N 3.47Å; L364-S368 WeakPolarHBondContact O-CB 3.43Å; L364-S368 PolarHBondContact O-N 3.46Å; L364-S368 PolarHBondContact O-OG 2.98Å; L364-N399 WeakPolarHBondContact CA-ND2 3.49Å; L364-N399 WeakPolarHBondContact CB-ND2 3.36Å; L364-N399 WeakPolarHBondContact CD1-ND2 3.45Å
365L97.8Very high94.6Very high0 Ų032 Ų320%016%0.157CC..Hα-helixtrans-58.4-52.5-179.6171.356.5000111.3V324 Y347 L350 L351 D354 L357 S361 Q362 Y367 S368 Y369V324-L365 HydrophobicContact CG1-CB 4.16Å; Y347-L365 HydrophobicContact CD1-CD1 4.13Å; L350-L365 HydrophobicContact CB-CD1 3.51Å; L350-L365 HydrophobicContact CB-CD2 3.99Å; L350-L365 HydrophobicContact CB-CG 4.4Å; L350-L365 HydrophobicContact CD1-CD1 3.94Å; L350-L365 HydrophobicContact CG-CD1 4.33Å; L350-L365 WeakPolarHBondContact O-CD2 3.48Å; L351-L365 HydrophobicContact CD2-CD1 4.49Å; L351-L365 HydrophobicContact CD2-CD2 4.02Å; L351-L365 HydrophobicContact CD2-CG 4.11Å; L351-L365 HydrophobicContact CG-CD2 4.47Å; D354-L365 HydrophobicContact CB-CD2 4.22Å; L357-L365 HydrophobicContact CD1-CD2 3.9Å; S361-L365 WeakPolarHBondContact O-CB 3.48Å; S361-L365 PolarHBondContact O-N 3.49Å; Q362-L365 PolarHBondContact O-N 3.28Å; L365-Y367 PolarHBondContact O-N 3.28Å; L365-S368 PolarHBondContact O-N 2.96Å; L365-Y369 WeakPolarHBondContact O-CB 3.44Å; L365-Y369 PolarHBondContact O-N 3.38Å
366Y98.1Very high94.3Very high21 Ų2127.3 Ų27.38%0.08214%0.138CC..Hα-helixtrans-63.1-41.4-178.9-63.2-20.1000111.7L351 D354 Q362 A370 F386 K389 I393L351-Y366 HydrophobicContact CD2-CD1 3.99Å; L351-Y366 HydrophobicContact CD2-CE1 3.89Å; D354-Y366 PolarHBondContact OD2-OH 3.02Å; Q362-Y366 HydrophobicContact CB-CE2 4.15Å; Q362-Y366 WeakPolarHBondContact O-CB 3.19Å; Q362-Y366 WeakPolarHBondContact O-CD2 3.47Å; Q362-Y366 VanDerWaalsContact O-CG 3.26Å; Q362-Y366 PolarHBondContact O-N 3.45Å; Y366-A370 VanDerWaalsContact O-CB 3.24Å; Y366-A370 WeakPolarHBondContact O-CB 3.45Å; Y366-A370 PolarHBondContact O-N 3.38Å; Y366-F386 AromaticContact CD1-CD1 3.74Å; Y366-F386 HydrophobicContact CD1-CD1 3.74Å; Y366-F386 AromaticContact CD1-CE1 3.92Å; Y366-F386 HydrophobicContact CD1-CE1 3.92Å; Y366-F386 HydrophobicContact CE1-CD1 4.5Å; Y366-F386 HydrophobicContact CE1-CE1 4.3Å; Y366-F386 HydrophobicContact CG-CD1 4.09Å; Y366-K389 HydrophobicContact CD2-CB 3.81Å; Y366-K389 HydrophobicContact CE2-CB 4.11Å; Y366-K389 HydrophobicContact CG-CB 4.38Å; Y366-I393 HydrophobicContact CD2-CD1 4.1Å; Y366-I393 HydrophobicContact CE2-CD1 3.94Å
367Y97.4Very high93.5Very high48 Ų4829.2 Ų29.219%0.18816%0.163CC..Hα-helixtrans-61-51.7173.1170.8-107.8000112Q363 L364 L365 Y369 A370 C371 L387 N399 K402 C403 I406Q363-Y367 WeakPolarHBondContact O-CB 3.41Å; Q363-Y367 PolarHBondContact O-N 3.21Å; L364-Y367 PolarHBondContact O-N 3.47Å; L365-Y367 PolarHBondContact O-N 3.28Å; Y367-Y369 VanDerWaalsContact C-N 3.31Å; Y367-Y369 PolarHBondContact O-N 2.9Å; Y367-A370 PolarHBondContact O-N 3.38Å; Y367-C371 VanDerWaalsContact CE2-SG 3.59Å; Y367-C371 PolarHBondContact O-N 3.05Å; Y367-C371 PolarHBondContact O-SG 3.13Å; Y367-C371 VanDerWaalsContact O-SG 3.41Å; Y367-L387 HydrophobicContact CD2-CD2 4.3Å; Y367-N399 HydrophobicContact CD1-CB 4.36Å; Y367-N399 HydrophobicContact CG-CB 4.24Å; Y367-K402 HydrophobicContact CD2-CB 4.3Å; Y367-K402 HydrophobicContact CE2-CB 3.74Å; Y367-C403 VanDerWaalsContact CD2-SG 3.59Å; Y367-I406 HydrophobicContact CE2-CD1 3.87Å
368S96.4Very high92.6Very high17 Ų1733.4 Ų33.412%0.11918%0.183CC..Hα-helixtrans-59.2-42.5-179.9-73.10000111.9Y347 L364 L365 C371 Y372Y347-S368 PolarHBondContact OH-O 3.03Å; L364-S368 WeakPolarHBondContact O-CB 3.43Å; L364-S368 PolarHBondContact O-N 3.46Å; L364-S368 PolarHBondContact O-OG 2.98Å; L365-S368 PolarHBondContact O-N 2.96Å; S368-C371 PolarHBondContact O-N 3.34Å; S368-Y372 PolarHBondContact O-N 3.16Å
369Y96.9Very high92.1Very high1 Ų135.4 Ų35.40%0.00420%0.197CC..Hα-helixtrans-69.5-41.4177.6-171-125.4000112.3E344 Y347 Q348 L351 L365 Y367 C371 Y372 V373 K382 F386E344-Y369 PolarHBondContact OE1-OH 2.86Å; E344-Y369 WeakPolarHBondContact OE2-CE2 3.39Å; E344-Y369 PolarHBondContact OE2-OH 2.98Å; Y347-Y369 VanDerWaalsContact CB-CD2 3.47Å; Y347-Y369 AromaticContact CD1-CD2 3.86Å; Y347-Y369 HydrophobicContact CD1-CD2 3.86Å; Y347-Y369 HydrophobicContact CD1-CG 4.36Å; Y347-Y369 AromaticContact CD2-CD2 3.72Å; Y347-Y369 HydrophobicContact CD2-CD2 3.72Å; Y347-Y369 HydrophobicContact CD2-CE2 4.2Å; Y347-Y369 HydrophobicContact CE2-CD2 4.41Å; Y347-Y369 AromaticContact CG-CD2 3.42Å; Y347-Y369 HydrophobicContact CG-CD2 3.42Å; Y347-Y369 VanDerWaalsContact CG-CD2 3.42Å; Y347-Y369 HydrophobicContact CG-CE2 4.02Å; Y347-Y369 HydrophobicContact CG-CG 4.33Å; Q348-Y369 PolarHBondContact NE2-OH 3.08Å; L351-Y369 HydrophobicContact CD1-CD1 3.79Å; L351-Y369 HydrophobicContact CD1-CE1 3.68Å; L351-Y369 HydrophobicContact CD1-CG 4.27Å; L365-Y369 WeakPolarHBondContact O-CB 3.44Å; L365-Y369 PolarHBondContact O-N 3.38Å; Y367-Y369 VanDerWaalsContact C-N 3.31Å; Y367-Y369 PolarHBondContact O-N 2.9Å; Y369-C371 VanDerWaalsContact C-N 3.29Å; Y369-C371 PolarHBondContact O-N 3.15Å; Y369-Y372 AromaticContact CD2-CD1 4Å; Y369-Y372 HydrophobicContact CD2-CD1 4Å; Y369-Y372 AromaticContact CE2-CD1 3.86Å; Y369-Y372 HydrophobicContact CE2-CD1 3.86Å; Y369-Y372 HydrophobicContact CE2-CE1 4.29Å; Y369-Y372 WeakPolarHBondContact O-CB 3.16Å; Y369-Y372 PolarHBondContact O-N 3.42Å; Y369-Y372 VanDerWaalsContact O-N 3.12Å; Y369-V373 HydrophobicContact CD1-CG2 4.19Å; Y369-V373 HydrophobicContact CD2-CG2 4.12Å; Y369-V373 HydrophobicContact CE1-CG2 3.85Å; Y369-V373 HydrophobicContact CE2-CG2 3.78Å; Y369-V373 HydrophobicContact CG-CG2 4.32Å; Y369-V373 WeakPolarHBondContact O-CG2 3.23Å; Y369-V373 PolarHBondContact O-N 2.91Å; Y369-K382 WeakPolarHBondContact OH-CE 3.33Å; Y369-K382 PolarHBondContact OH-NZ 3.05Å; Y369-F386 HydrophobicContact CD1-CD1 4.06Å; Y369-F386 AromaticContact CD1-CD2 3.62Å; Y369-F386 HydrophobicContact CD1-CD2 3.62Å; Y369-F386 AromaticContact CD1-CE1 3.89Å; Y369-F386 HydrophobicContact CD1-CE1 3.89Å; Y369-F386 AromaticContact CD1-CE2 3.46Å; Y369-F386 HydrophobicContact CD1-CE2 3.46Å; Y369-F386 VanDerWaalsContact CD1-CE2 3.46Å; Y369-F386 AromaticContact CD1-CG 3.93Å; Y369-F386 HydrophobicContact CD1-CG 3.93Å; Y369-F386 AromaticContact CD1-CZ 3.59Å; Y369-F386 HydrophobicContact CD1-CZ 3.59Å; Y369-F386 AromaticContact CE1-CD2 3.91Å; Y369-F386 HydrophobicContact CE1-CD2 3.91Å; Y369-F386 HydrophobicContact CE1-CE1 4.4Å; Y369-F386 AromaticContact CE1-CE2 3.37Å; Y369-F386 HydrophobicContact CE1-CE2 3.37Å; Y369-F386 AromaticContact CE1-CZ 3.64Å; Y369-F386 HydrophobicContact CE1-CZ 3.64Å
370A96.3Very high91.7Very high0 Ų043.8 Ų43.80%023%0.226CC..Hα-helixtrans-57.8-43.1174.100000111.9Y366 Y367 H374 S383 F386 L387Y366-A370 VanDerWaalsContact O-CB 3.24Å; Y366-A370 WeakPolarHBondContact O-CB 3.45Å; Y366-A370 PolarHBondContact O-N 3.38Å; Y367-A370 PolarHBondContact O-N 3.38Å; A370-H374 WeakPolarHBondContact O-CB 3.39Å; A370-H374 PolarHBondContact O-N 3.41Å; A370-S383 WeakPolarHBondContact CB-O 3.35Å; A370-S383 WeakPolarHBondContact O-CB 3.42Å; A370-S383 PolarHBondContact O-OG 3.21Å; A370-F386 HydrophobicContact CB-CB 3.78Å; A370-L387 HydrophobicContact CB-CD2 3.6Å; A370-L387 HydrophobicContact CB-CG 3.74Å
371C93.7Very high91.5Very high32 Ų3244.7 Ų44.722%0.21623%0.233CC..Hα-helixtrans-61.9-47.5173.3-70.30000111.2Y367 S368 Y369 V373 H374 H375Y367-C371 VanDerWaalsContact CE2-SG 3.59Å; Y367-C371 PolarHBondContact O-N 3.05Å; Y367-C371 PolarHBondContact O-SG 3.13Å; Y367-C371 VanDerWaalsContact O-SG 3.41Å; S368-C371 PolarHBondContact O-N 3.34Å; Y369-C371 VanDerWaalsContact C-N 3.29Å; Y369-C371 PolarHBondContact O-N 3.15Å; C371-V373 PolarHBondContact O-N 3.43Å; C371-H374 PolarHBondContact O-N 3.28Å; C371-H375 PolarHBondContact O-N 3.24Å; C371-H375 PolarHBondContact O-ND1 3.4Å
372Y94.4Very high91.4Very high4 Ų447 Ų472%0.01624%0.241CC..Hα-helixtrans-56.6-51.5178.5166.9-90.8000112R335 T340 A343 E344 Y347 S368 Y369 H374 H375 T376R335-Y372 HydrophobicContact CB-CD2 4.09Å; R335-Y372 HydrophobicContact CB-CE2 4.11Å; R335-Y372 HydrophobicContact CG-CD2 4.15Å; R335-Y372 HydrophobicContact CG-CE2 4.19Å; T340-Y372 PolarHBondContact O-OH 2.94Å; A343-Y372 HydrophobicContact CB-CD2 4.18Å; A343-Y372 HydrophobicContact CB-CE2 3.43Å; A343-Y372 VanDerWaalsContact CB-CE2 3.43Å; E344-Y372 WeakPolarHBondContact OE2-CE1 3.2Å; Y347-Y372 HydrophobicContact CD2-CD1 4.02Å; Y347-Y372 HydrophobicContact CD2-CD2 4.18Å; Y347-Y372 AromaticContact CD2-CG 3.84Å; Y347-Y372 HydrophobicContact CD2-CG 3.84Å; Y347-Y372 VanDerWaalsContact CE2-CB 3.49Å; Y347-Y372 HydrophobicContact CE2-CD1 4.15Å; Y347-Y372 AromaticContact CE2-CD2 3.72Å; Y347-Y372 HydrophobicContact CE2-CD2 3.72Å; Y347-Y372 AromaticContact CE2-CG 3.5Å; Y347-Y372 HydrophobicContact CE2-CG 3.5Å; Y347-Y372 VanDerWaalsContact CE2-CG 3.5Å; S368-Y372 PolarHBondContact O-N 3.16Å; Y369-Y372 AromaticContact CD2-CD1 4Å; Y369-Y372 HydrophobicContact CD2-CD1 4Å; Y369-Y372 AromaticContact CE2-CD1 3.86Å; Y369-Y372 HydrophobicContact CE2-CD1 3.86Å; Y369-Y372 HydrophobicContact CE2-CE1 4.29Å; Y369-Y372 WeakPolarHBondContact O-CB 3.16Å; Y369-Y372 PolarHBondContact O-N 3.42Å; Y369-Y372 VanDerWaalsContact O-N 3.12Å; Y372-H374 VanDerWaalsContact C-N 3.28Å; Y372-H374 PolarHBondContact O-N 2.88Å; Y372-H375 PolarHBondContact O-N 3.24Å; Y372-H375 VanDerWaalsContact O-N 3.15Å; Y372-T376 HydrophobicContact CD2-CG2 4.11Å; Y372-T376 HydrophobicContact CE1-CG2 4.16Å; Y372-T376 HydrophobicContact CE2-CG2 3.64Å; Y372-T376 PolarHBondContact O-N 3.49Å; Y372-T376 PolarHBondContact O-OG1 2.89Å; Y372-T376 VanDerWaalsContact O-OG1 3.07Å
373V93.3Very high91.3Very high0 Ų045.4 Ų45.40%023%0.234CC..Hα-helixtrans-61-37.8-179.5171.70000111.6Y369 C371 T376 G377 Q378 S379 K382Y369-V373 HydrophobicContact CD1-CG2 4.19Å; Y369-V373 HydrophobicContact CD2-CG2 4.12Å; Y369-V373 HydrophobicContact CE1-CG2 3.85Å; Y369-V373 HydrophobicContact CE2-CG2 3.78Å; Y369-V373 HydrophobicContact CG-CG2 4.32Å; Y369-V373 WeakPolarHBondContact O-CG2 3.23Å; Y369-V373 PolarHBondContact O-N 2.91Å; C371-V373 PolarHBondContact O-N 3.43Å; V373-T376 PolarHBondContact O-OG1 3.34Å; V373-G377 PolarHBondContact O-N 3.08Å; V373-Q378 HydrophobicContact CG1-CB 4.32Å; V373-S379 VanDerWaalsContact CG1-O 3.24Å; V373-S379 WeakPolarHBondContact CG1-O 3.29Å; V373-K382 HydrophobicContact CG1-CB 3.94Å; V373-K382 HydrophobicContact CG1-CD 4.04Å; V373-K382 HydrophobicContact CG1-CG 4.06Å; V373-K382 HydrophobicContact CG2-CD 4.26Å
374H90.5Very high91.2Very high111 Ų11145.8 Ų45.851%0.51424%0.236SC..Hα-helixtrans-63-46.5175.4-176.778.9000111.9A370 C371 Y372 G377A370-H374 WeakPolarHBondContact O-CB 3.39Å; A370-H374 PolarHBondContact O-N 3.41Å; C371-H374 PolarHBondContact O-N 3.28Å; Y372-H374 VanDerWaalsContact C-N 3.28Å; Y372-H374 PolarHBondContact O-N 2.88Å; H374-G377 PolarHBondContact O-N 3.3Å
375H85.9Confident91.2Very high115 Ų11547.6 Ų47.653%0.53225%0.246SC..Hα-helixtrans-73.1-29.5-175.7-73.984.6000113.6C371 Y372 G377C371-H375 PolarHBondContact O-N 3.24Å; C371-H375 PolarHBondContact O-ND1 3.4Å; Y372-H375 PolarHBondContact O-N 3.24Å; Y372-H375 VanDerWaalsContact O-N 3.15Å; H375-G377 VanDerWaalsContact C-N 3.28Å
376T85.6Confident91.2Very high41 Ų4148.9 Ų48.925%0.25225%0.251SS..THydrogen-bonded Turntrans-82.7-6.4178.153.10000113.1R335 T340 Y372 V373 Q378R335-T376 HydrophobicContact CG-CG2 4.23Å; T340-T376 HydrophobicContact CG2-CG2 4.06Å; Y372-T376 HydrophobicContact CD2-CG2 4.11Å; Y372-T376 HydrophobicContact CE1-CG2 4.16Å; Y372-T376 HydrophobicContact CE2-CG2 3.64Å; Y372-T376 PolarHBondContact O-N 3.49Å; Y372-T376 PolarHBondContact O-OG1 2.89Å; Y372-T376 VanDerWaalsContact O-OG1 3.07Å; V373-T376 PolarHBondContact O-OG1 3.34Å; T376-Q378 PolarHBondContact O-N 3.5Å; T376-Q378 WeakPolarHBondContact OG1-CG 3.48Å
377G78.2Confident91.2Very high66 Ų6648.1 Ų48.168%0.6825%0.249SC*.THydrogen-bonded Turntrans72.28.3179.200000114.4V373 H374 H375V373-G377 PolarHBondContact O-N 3.08Å; H374-G377 PolarHBondContact O-N 3.3Å; H375-G377 VanDerWaalsContact C-N 3.28Å
378Q74.8Confident91.2Very high90 Ų9046.8 Ų46.842%0.42124%0.244SC..SBendtrans-61.2-47.2-175.8-74.8179.4-1.400112.9V373 T376V373-Q378 HydrophobicContact CG1-CB 4.32Å; T376-Q378 PolarHBondContact O-N 3.5Å; T376-Q378 WeakPolarHBondContact OG1-CG 3.48Å
379S83.9Confident91.2Very high43 Ų4350.7 Ų50.730%0.30126%0.259SS..  trans-169124.3175.4169.90000112.2V373 D381 K382 S383V373-S379 VanDerWaalsContact CG1-O 3.24Å; V373-S379 WeakPolarHBondContact CG1-O 3.29Å; S379-D381 VanDerWaalsContact C-N 3.35Å; S379-D381 PolarHBondContact OG-N 3.33Å; S379-K382 PolarHBondContact OG-N 3Å; S379-S383 PolarHBondContact O-N 2.88Å
380R84.6Confident91.2Very high192 Ų19250.6 Ų50.673%0.72526%0.259SS*.Hα-helixtrans-64.4-40.2173.4-70.4-178.2-179.5171.12.1111.7S383 I384R380-S383 WeakPolarHBondContact O-CB 3.49Å; R380-S383 PolarHBondContact O-N 3.06Å; R380-I384 WeakPolarHBondContact O-CG1 3.26Å; R380-I384 PolarHBondContact O-N 3.31Å
381D89.1Confident91.2Very high70 Ų7050.6 Ų50.637%0.37426%0.259SS..Hα-helixtrans-67.8-38.4-179.2-67.7-37.5000112.4S379 S383 I384 N385 R418S379-D381 VanDerWaalsContact C-N 3.35Å; S379-D381 PolarHBondContact OG-N 3.33Å; D381-S383 VanDerWaalsContact C-N 3.34Å; D381-S383 PolarHBondContact O-N 3.43Å; D381-I384 PolarHBondContact O-N 3Å; D381-N385 VanDerWaalsContact O-CG 3.27Å; D381-N385 PolarHBondContact O-N 3.44Å; D381-N385 PolarHBondContact O-ND2 3.46Å; D381-R418 WeakPolarHBondContact OD1-CD 3.29Å
382K92.8Very high91.3Very high65 Ų6555.2 Ų55.228%0.28328%0.278SS..Hα-helixtrans-61.8-43.8174.5-173.5178.6179.3-174.10110.8E344 Y369 V373 S379 N385 F386E344-K382 IonicContact OE1-NZ 3.92Å; Y369-K382 WeakPolarHBondContact OH-CE 3.33Å; Y369-K382 PolarHBondContact OH-NZ 3.05Å; V373-K382 HydrophobicContact CG1-CB 3.94Å; V373-K382 HydrophobicContact CG1-CD 4.04Å; V373-K382 HydrophobicContact CG1-CG 4.06Å; V373-K382 HydrophobicContact CG2-CD 4.26Å; S379-K382 PolarHBondContact OG-N 3Å; K382-N385 PolarHBondContact O-N 3.42Å; K382-F386 HydrophobicContact CG-CD2 4.27Å; K382-F386 HydrophobicContact CG-CE2 4.19Å; K382-F386 WeakPolarHBondContact O-CD2 3.3Å; K382-F386 PolarHBondContact O-N 3.2Å
383S94.9Very high91.3Very high7 Ų756.4 Ų56.45%0.04928%0.284CS..Hα-helixtrans-58.7-49.2174.2-178.40000111.8A370 S379 R380 D381 N385 F386 L387A370-S383 WeakPolarHBondContact CB-O 3.35Å; A370-S383 WeakPolarHBondContact O-CB 3.42Å; A370-S383 PolarHBondContact O-OG 3.21Å; S379-S383 PolarHBondContact O-N 2.88Å; R380-S383 WeakPolarHBondContact O-CB 3.49Å; R380-S383 PolarHBondContact O-N 3.06Å; D381-S383 VanDerWaalsContact C-N 3.34Å; D381-S383 PolarHBondContact O-N 3.43Å; S383-N385 VanDerWaalsContact C-N 3.33Å; S383-N385 PolarHBondContact O-N 2.89Å; S383-F386 PolarHBondContact O-N 3.42Å; S383-L387 WeakPolarHBondContact O-CG 3.48Å; S383-L387 PolarHBondContact O-N 2.99Å
384I95.4Very high91.1Very high8 Ų863.8 Ų63.84%0.04132%0.316CS..Hα-helixtrans-57.8-43.1177.4-67.2-64.9000111.9R380 D381 F386 L387 M388 L407 T410 I422R380-I384 WeakPolarHBondContact O-CG1 3.26Å; R380-I384 PolarHBondContact O-N 3.31Å; D381-I384 PolarHBondContact O-N 3Å; I384-F386 VanDerWaalsContact C-N 3.33Å; I384-F386 PolarHBondContact O-N 2.89Å; I384-L387 HydrophobicContact CD1-CD1 4.33Å; I384-L387 PolarHBondContact O-N 3.21Å; I384-M388 HydrophobicContact CG2-CG 4.37Å; I384-M388 HydrophobicContact CG2-SD 3.83Å; I384-M388 WeakPolarHBondContact O-CG 3.31Å; I384-M388 PolarHBondContact O-N 3.41Å; I384-L407 HydrophobicContact CD1-CD2 4.03Å; I384-L407 HydrophobicContact CG2-CD2 4.21Å; I384-T410 HydrophobicContact CD1-CG2 4Å; I384-I422 HydrophobicContact CD1-CD1 4.19Å; I384-I422 HydrophobicContact CG2-CD1 3.95Å; I384-I422 HydrophobicContact CG2-CG1 4.15Å
385N96.1Very high90.9Very high69 Ų6961.7 Ų61.737%0.36931%0.309SS..Hα-helixtrans-59-43.3178.3-73.1-17.1000112.2D381 K382 S383 M388 K389 R418D381-N385 VanDerWaalsContact O-CG 3.27Å; D381-N385 PolarHBondContact O-N 3.44Å; D381-N385 PolarHBondContact O-ND2 3.46Å; K382-N385 PolarHBondContact O-N 3.42Å; S383-N385 VanDerWaalsContact C-N 3.33Å; S383-N385 PolarHBondContact O-N 2.89Å; N385-M388 PolarHBondContact O-N 2.86Å; N385-K389 WeakPolarHBondContact O-CG 3.45Å; N385-K389 PolarHBondContact O-N 2.95Å; N385-R418 VanDerWaalsContact OD1-CZ 3.29Å; N385-R418 PolarHBondContact OD1-NH1 3.3Å; N385-R418 PolarHBondContact OD1-NH2 3.01Å
386F97.1Very high90.8Very high26 Ų2660.9 Ų60.911%0.11430%0.301CS..Hα-helixtrans-71.5-33.8178.1-82.8-77.7000112.9L351 Y366 Y369 A370 K382 S383 I384 M388 K389 A390L351-F386 HydrophobicContact CD1-CE1 4.39Å; L351-F386 HydrophobicContact CD1-CZ 4.12Å; L351-F386 HydrophobicContact CD2-CE1 3.61Å; L351-F386 HydrophobicContact CD2-CZ 4.14Å; Y366-F386 AromaticContact CD1-CD1 3.74Å; Y366-F386 HydrophobicContact CD1-CD1 3.74Å; Y366-F386 AromaticContact CD1-CE1 3.92Å; Y366-F386 HydrophobicContact CD1-CE1 3.92Å; Y366-F386 HydrophobicContact CE1-CD1 4.5Å; Y366-F386 HydrophobicContact CE1-CE1 4.3Å; Y366-F386 HydrophobicContact CG-CD1 4.09Å; Y369-F386 HydrophobicContact CD1-CD1 4.06Å; Y369-F386 AromaticContact CD1-CD2 3.62Å; Y369-F386 HydrophobicContact CD1-CD2 3.62Å; Y369-F386 AromaticContact CD1-CE1 3.89Å; Y369-F386 HydrophobicContact CD1-CE1 3.89Å; Y369-F386 AromaticContact CD1-CE2 3.46Å; Y369-F386 HydrophobicContact CD1-CE2 3.46Å; Y369-F386 VanDerWaalsContact CD1-CE2 3.46Å; Y369-F386 AromaticContact CD1-CG 3.93Å; Y369-F386 HydrophobicContact CD1-CG 3.93Å; Y369-F386 AromaticContact CD1-CZ 3.59Å; Y369-F386 HydrophobicContact CD1-CZ 3.59Å; Y369-F386 AromaticContact CE1-CD2 3.91Å; Y369-F386 HydrophobicContact CE1-CD2 3.91Å; Y369-F386 HydrophobicContact CE1-CE1 4.4Å; Y369-F386 AromaticContact CE1-CE2 3.37Å; Y369-F386 HydrophobicContact CE1-CE2 3.37Å; Y369-F386 AromaticContact CE1-CZ 3.64Å; Y369-F386 HydrophobicContact CE1-CZ 3.64Å; A370-F386 HydrophobicContact CB-CB 3.78Å; K382-F386 HydrophobicContact CG-CD2 4.27Å; K382-F386 HydrophobicContact CG-CE2 4.19Å; K382-F386 WeakPolarHBondContact O-CD2 3.3Å; K382-F386 PolarHBondContact O-N 3.2Å; S383-F386 PolarHBondContact O-N 3.42Å; I384-F386 VanDerWaalsContact C-N 3.33Å; I384-F386 PolarHBondContact O-N 2.89Å; F386-M388 VanDerWaalsContact C-N 3.34Å; F386-K389 HydrophobicContact CD1-CD 4.24Å; F386-K389 HydrophobicContact CE1-CD 4.38Å; F386-K389 PolarHBondContact O-N 3.44Å; F386-A390 PolarHBondContact O-N 3.33Å
387L97.6Very high90.9Very high5 Ų559.4 Ų59.43%0.02629%0.293CS..Hα-helixtrans-62-42.9171.1-64.9174.9000111.4Y367 A370 S383 I384 A390 A391 C403 I406 L407Y367-L387 HydrophobicContact CD2-CD2 4.3Å; A370-L387 HydrophobicContact CB-CD2 3.6Å; A370-L387 HydrophobicContact CB-CG 3.74Å; S383-L387 WeakPolarHBondContact O-CG 3.48Å; S383-L387 PolarHBondContact O-N 2.99Å; I384-L387 HydrophobicContact CD1-CD1 4.33Å; I384-L387 PolarHBondContact O-N 3.21Å; L387-A390 PolarHBondContact O-N 3.49Å; L387-A391 WeakPolarHBondContact O-CB 3.5Å; L387-A391 PolarHBondContact O-N 2.78Å; L387-C403 HydrophobicContact CB-CB 4.37Å; L387-C403 HydrophobicContact CD2-CB 4.18Å; L387-C403 VanDerWaalsContact CD2-SG 3.57Å; L387-I406 HydrophobicContact CD1-CB 4.18Å; L387-I406 HydrophobicContact CD1-CG2 3.51Å; L387-I406 HydrophobicContact CD2-CD1 4.35Å; L387-L407 HydrophobicContact CB-CD1 4.19Å; L387-L407 HydrophobicContact CB-CD2 3.96Å; L387-L407 HydrophobicContact CB-CG 4Å; L387-L407 HydrophobicContact CD1-CD2 4.3Å
388M96.9Very high91.4Very high20 Ų2060.5 Ų60.510%0.09928%0.277CS..Hα-helixtrans-63.9-46.7176.1-68.9171.871.700111.2I384 N385 F386 A390 A391 E392 L407 F425I384-M388 HydrophobicContact CG2-CG 4.37Å; I384-M388 HydrophobicContact CG2-SD 3.83Å; I384-M388 WeakPolarHBondContact O-CG 3.31Å; I384-M388 PolarHBondContact O-N 3.41Å; N385-M388 PolarHBondContact O-N 2.86Å; F386-M388 VanDerWaalsContact C-N 3.34Å; M388-A390 VanDerWaalsContact C-N 3.29Å; M388-A390 PolarHBondContact O-N 3.18Å; M388-A391 PolarHBondContact O-N 3.27Å; M388-E392 WeakPolarHBondContact O-CB 3.39Å; M388-E392 PolarHBondContact O-N 3.01Å; M388-L407 HydrophobicContact CG-CD1 4.03Å; M388-L407 HydrophobicContact CG-CD2 4.06Å; M388-F425 HydrophobicContact CB-CD1 4.49Å; M388-F425 HydrophobicContact CB-CE1 4.06Å; M388-F425 HydrophobicContact CB-CE2 4.21Å; M388-F425 HydrophobicContact CB-CZ 3.9Å; M388-F425 HydrophobicContact CE-CB 3.73Å; M388-F425 HydrophobicContact CE-CD1 4.11Å; M388-F425 HydrophobicContact CE-CD2 3.67Å; M388-F425 HydrophobicContact CE-CE2 4.32Å; M388-F425 HydrophobicContact CE-CG 3.55Å; M388-F425 HydrophobicContact CG-CD1 4.02Å; M388-F425 HydrophobicContact CG-CE1 3.98Å; M388-F425 HydrophobicContact CG-CG 4.4Å; M388-F425 HydrophobicContact CG-CZ 4.32Å; M388-F425 VanDerWaalsContact O-CZ 3.22Å; M388-F425 WeakPolarHBondContact O-CZ 3.34Å
389K96.8Very high92.2Very high99 Ų9957.2 Ų57.243%0.4326%0.262SS..Hα-helixtrans-54.8-43.4174.8-76.2-177.3172.2-167.10112.7Y366 N385 F386Y366-K389 HydrophobicContact CD2-CB 3.81Å; Y366-K389 HydrophobicContact CE2-CB 4.11Å; Y366-K389 HydrophobicContact CG-CB 4.38Å; N385-K389 WeakPolarHBondContact O-CG 3.45Å; N385-K389 PolarHBondContact O-N 2.95Å; F386-K389 HydrophobicContact CD1-CD 4.24Å; F386-K389 HydrophobicContact CE1-CD 4.38Å; F386-K389 PolarHBondContact O-N 3.44Å
390A97Very high92.6Very high0 Ų055.5 Ų55.50%025%0.249CC..Hα-helixtrans-65.7-41.3176.400000112.3Q363 F386 L387 M388 C403Q363-A390 WeakPolarHBondContact CG-O 3.45Å; Q363-A390 PolarHBondContact NE2-O 3.49Å; F386-A390 PolarHBondContact O-N 3.33Å; L387-A390 PolarHBondContact O-N 3.49Å; M388-A390 VanDerWaalsContact C-N 3.29Å; M388-A390 PolarHBondContact O-N 3.18Å; A390-C403 HydrophobicContact CB-CB 4.22Å; A390-C403 WeakPolarHBondContact CB-SG 3.42Å
391A96.4Very high93Very high0 Ų047.7 Ų47.70%022%0.222CC..Hα-helixtrans-70.7-29.6-179.600000113.2L387 M388 I393 K400 C403 I404 L407 F425 V429L387-A391 WeakPolarHBondContact O-CB 3.5Å; L387-A391 PolarHBondContact O-N 2.78Å; M388-A391 PolarHBondContact O-N 3.27Å; A391-I393 VanDerWaalsContact C-N 3.32Å; A391-K400 WeakPolarHBondContact O-CE 3.47Å; A391-C403 HydrophobicContact CB-CB 4.33Å; A391-I404 HydrophobicContact CB-CG1 3.93Å; A391-L407 HydrophobicContact CB-CD1 4.23Å; A391-F425 HydrophobicContact CB-CE1 3.8Å; A391-F425 HydrophobicContact CB-CZ 3.92Å; A391-V429 VanDerWaalsContact O-CG1 3.29Å; A391-V429 WeakPolarHBondContact O-CG1 3.27Å
392E96Very high93.2Very high129 Ų12946.5 Ų46.560%0.60321%0.214SC*.Hα-helixtrans-70-27.7179.4-173.3171.7-162.500112.9M388 K394 F425M388-E392 WeakPolarHBondContact O-CB 3.39Å; M388-E392 PolarHBondContact O-N 3.01Å; E392-K394 PolarHBondContact O-N 3.48Å; E392-F425 HydrophobicContact CB-CE2 4.12Å; E392-F425 HydrophobicContact CB-CZ 4.14Å
393I94.3Very high93.3Very high28 Ų2843.4 Ų43.414%0.14420%0.2CC..SBendtrans-64.3119.9175.8-65166.9000109.2P359 Q362 Q363 Y366 A391 N395 K400P359-I393 HydrophobicContact CB-CG2 3.63Å; Q362-I393 HydrophobicContact CB-CD1 3.7Å; Q363-I393 HydrophobicContact CG-CB 3.79Å; Q363-I393 HydrophobicContact CG-CD1 3.69Å; Q363-I393 HydrophobicContact CG-CG1 4.33Å; Q363-I393 HydrophobicContact CG-CG2 3.9Å; Q363-I393 PolarHBondContact NE2-O 2.96Å; Y366-I393 HydrophobicContact CD2-CD1 4.1Å; Y366-I393 HydrophobicContact CE2-CD1 3.94Å; A391-I393 VanDerWaalsContact C-N 3.32Å; I393-N395 HydrophobicContact CG2-CB 4.48Å; I393-N395 PolarHBondContact O-N 3.39Å; I393-K400 VanDerWaalsContact O-CE 3.3Å; I393-K400 WeakPolarHBondContact O-CE 3.26Å
394K89.3Confident93.4Very high155 Ų15543.6 Ų43.667%0.67420%0.201SC*.  trans-58.3-42-171.7-69.1-174172.8-1730113.7E392 Y396 K400 E432E392-K394 PolarHBondContact O-N 3.48Å; K394-Y396 PolarHBondContact O-N 2.94Å; K394-K400 PolarHBondContact O-NZ 3.21Å; K394-K400 VanDerWaalsContact O-NZ 3.09Å; K394-E432 VanDerWaalsContact CE-OE2 3.23Å; K394-E432 WeakPolarHBondContact CE-OE2 3.46Å; K394-E432 IonicContact NZ-OE2 3.69Å
395N86.6Confident93.3Very high68 Ų6847.6 Ų47.636%0.36422%0.219SC..SBendtrans-54.7134.5-174.5-6482.4000112.8P359 Q363 I393 S397P359-N395 HydrophobicContact CB-CB 4Å; P359-N395 WeakPolarHBondContact CB-OD1 3.45Å; P359-N395 WeakPolarHBondContact CG-OD1 3.49Å; Q363-N395 PolarHBondContact NE2-O 3.18Å; Q363-N395 PolarHBondContact OE1-O 3.18Å; I393-N395 HydrophobicContact CG2-CB 4.48Å; I393-N395 PolarHBondContact O-N 3.39Å; N395-S397 PolarHBondContact O-N 3.28Å
396Y84.5Confident93.3Very high98 Ų9847 Ų4738%0.38422%0.215SC..  trans-67.5131.5174.9174.4-103.5000112.2K186 K394 D401K186-Y396 PolarHBondContact NZ-OH 3.39Å; K394-Y396 PolarHBondContact O-N 2.94Å; Y396-D401 WeakPolarHBondContact CE2-OD1 3.34Å; Y396-D401 VanDerWaalsContact CE2-OD2 3.3Å; Y396-D401 WeakPolarHBondContact CE2-OD2 3.49Å; Y396-D401 PolarHBondContact OH-OD2 3.4Å
397S87.3Confident93.3Very high10 Ų1045.8 Ų45.87%0.0721%0.21CC..  trans-156.1161168.981.10000112.6Q363 N395 N399 K400 D401Q363-S397 PolarHBondContact OE1-OG 2.9Å; N395-S397 PolarHBondContact O-N 3.28Å; S397-N399 PolarHBondContact O-N 2.91Å; S397-N399 PolarHBondContact OG-N 3.3Å; S397-K400 WeakPolarHBondContact O-CB 3.44Å; S397-K400 PolarHBondContact O-N 2.88Å; S397-K400 VanDerWaalsContact O-N 3.17Å; S397-K400 PolarHBondContact OG-N 2.91Å; S397-K400 VanDerWaalsContact OG-N 3.17Å; S397-D401 PolarHBondContact O-N 2.99Å; S397-D401 VanDerWaalsContact O-N 3.11Å
398Y88.4Confident93.1Very high88 Ų8849 Ų4935%0.34523%0.225SC..Hα-helixtrans-53.8-39.1172.3174.5-100.6000112.9L183 Y185 D401 K402L183-Y398 HydrophobicContact CD1-CD2 3.77Å; L183-Y398 HydrophobicContact CD1-CG 4.35Å; L183-Y398 HydrophobicContact CD2-CD2 4.25Å; Y185-Y398 HydrophobicContact CE1-CD2 4.13Å; Y185-Y398 HydrophobicContact CE1-CE2 4.01Å; Y185-Y398 WeakPolarHBondContact OH-CD2 3.45Å; Y185-Y398 WeakPolarHBondContact OH-CE2 3.25Å; Y398-D401 PolarHBondContact O-N 3.49Å; Y398-K402 HydrophobicContact CD1-CG 4.3Å; Y398-K402 HydrophobicContact CE1-CG 3.77Å; Y398-K402 HydrophobicContact CE2-CD 4.46Å; Y398-K402 HydrophobicContact CE2-CG 4.01Å; Y398-K402 WeakPolarHBondContact O-CG 3.48Å; Y398-K402 PolarHBondContact O-N 2.82Å; Y398-K402 WeakPolarHBondContact OH-CE 3.45Å
399N92.3Very high93Very high22 Ų2250.9 Ų50.912%0.11824%0.237CC..Hα-helixtrans-72.3-36.1-177.2-57.1-56.5000110.8Q363 L364 Y367 S397 K402 C403Q363-N399 HydrophobicContact CB-CB 4.3Å; L364-N399 WeakPolarHBondContact CA-ND2 3.49Å; L364-N399 WeakPolarHBondContact CB-ND2 3.36Å; L364-N399 WeakPolarHBondContact CD1-ND2 3.45Å; Y367-N399 HydrophobicContact CD1-CB 4.36Å; Y367-N399 HydrophobicContact CG-CB 4.24Å; S397-N399 PolarHBondContact O-N 2.91Å; S397-N399 PolarHBondContact OG-N 3.3Å; N399-K402 PolarHBondContact O-N 3.22Å; N399-C403 PolarHBondContact O-N 3.15Å; N399-C403 PolarHBondContact O-SG 3.46Å
400K92.5Very high92.8Very high6 Ų647.4 Ų47.43%0.02623%0.225CC..Hα-helixtrans-58.4-51.7171.6-171.1-173.6-174.7-166.70110.8A391 I393 K394 S397 K402 C403 I404 E433A391-K400 WeakPolarHBondContact O-CE 3.47Å; I393-K400 VanDerWaalsContact O-CE 3.3Å; I393-K400 WeakPolarHBondContact O-CE 3.26Å; K394-K400 PolarHBondContact O-NZ 3.21Å; K394-K400 VanDerWaalsContact O-NZ 3.09Å; S397-K400 WeakPolarHBondContact O-CB 3.44Å; S397-K400 PolarHBondContact O-N 2.88Å; S397-K400 VanDerWaalsContact O-N 3.17Å; S397-K400 PolarHBondContact OG-N 2.91Å; S397-K400 VanDerWaalsContact OG-N 3.17Å; K400-K402 VanDerWaalsContact C-N 3.29Å; K400-K402 PolarHBondContact O-N 3.48Å; K400-C403 WeakPolarHBondContact O-CB 3.38Å; K400-C403 PolarHBondContact O-N 3.09Å; K400-C403 VanDerWaalsContact O-N 3.13Å; K400-I404 HydrophobicContact CG-CD1 4.07Å; K400-I404 WeakPolarHBondContact O-CG1 3.48Å; K400-I404 PolarHBondContact O-N 3.21Å; K400-E433 VanDerWaalsContact CE-OE1 3.22Å; K400-E433 WeakPolarHBondContact CE-OE1 3.41Å; K400-E433 IonicContact NZ-OE1 3.74Å; K400-E433 PolarHBondContact NZ-OE1 3.39Å
401D91.2Very high92.6Very high28 Ų2848.6 Ų48.615%0.1523%0.232CC..Hα-helixtrans-55.6-45.7178.1-66.5-41.3000111.6K186 Y396 S397 Y398 I404 E405K186-D401 IonicContact NZ-OD1 3.8Å; K186-D401 PolarHBondContact NZ-OD1 2.86Å; K186-D401 IonicContact NZ-OD2 3.87Å; K186-D401 PolarHBondContact NZ-OD2 3.13Å; Y396-D401 WeakPolarHBondContact CE2-OD1 3.34Å; Y396-D401 VanDerWaalsContact CE2-OD2 3.3Å; Y396-D401 WeakPolarHBondContact CE2-OD2 3.49Å; Y396-D401 PolarHBondContact OH-OD2 3.4Å; S397-D401 PolarHBondContact O-N 2.99Å; S397-D401 VanDerWaalsContact O-N 3.11Å; Y398-D401 PolarHBondContact O-N 3.49Å; D401-I404 PolarHBondContact O-N 3.25Å; D401-E405 WeakPolarHBondContact O-CB 3.33Å; D401-E405 PolarHBondContact O-N 3.39Å
402K93.9Very high92.4Very high46 Ų4655.8 Ų55.820%0.227%0.265CS..Hα-helixtrans-64.8-39.5178.3-74.6-58-177.9-169.10112.9Y367 Y398 N399 K400 E405 I406Y367-K402 HydrophobicContact CD2-CB 4.3Å; Y367-K402 HydrophobicContact CE2-CB 3.74Å; Y398-K402 HydrophobicContact CD1-CG 4.3Å; Y398-K402 HydrophobicContact CE1-CG 3.77Å; Y398-K402 HydrophobicContact CE2-CD 4.46Å; Y398-K402 HydrophobicContact CE2-CG 4.01Å; Y398-K402 WeakPolarHBondContact O-CG 3.48Å; Y398-K402 PolarHBondContact O-N 2.82Å; Y398-K402 WeakPolarHBondContact OH-CE 3.45Å; N399-K402 PolarHBondContact O-N 3.22Å; K400-K402 VanDerWaalsContact C-N 3.29Å; K400-K402 PolarHBondContact O-N 3.48Å; K402-E405 WeakPolarHBondContact CD-OE2 3.37Å; K402-E405 IonicContact NZ-OE1 2.78Å; K402-E405 IonicContact NZ-OE2 3.34Å; K402-E405 PolarHBondContact NZ-OE2 2.95Å; K402-E405 PolarHBondContact O-N 2.91Å; K402-I406 WeakPolarHBondContact O-CB 3.39Å; K402-I406 WeakPolarHBondContact O-CD1 3.46Å; K402-I406 WeakPolarHBondContact O-CG1 3.25Å; K402-I406 PolarHBondContact O-N 3.27Å
403C95.9Very high92.1Very high0 Ų054.5 Ų54.50%026%0.262CS..Hα-helixtrans-61.5-45.6173.5-69.80000111.7Y367 L387 A390 A391 N399 K400 I406 L407Y367-C403 VanDerWaalsContact CD2-SG 3.59Å; L387-C403 HydrophobicContact CB-CB 4.37Å; L387-C403 HydrophobicContact CD2-CB 4.18Å; L387-C403 VanDerWaalsContact CD2-SG 3.57Å; A390-C403 HydrophobicContact CB-CB 4.22Å; A390-C403 WeakPolarHBondContact CB-SG 3.42Å; A391-C403 HydrophobicContact CB-CB 4.33Å; N399-C403 PolarHBondContact O-N 3.15Å; N399-C403 PolarHBondContact O-SG 3.46Å; K400-C403 WeakPolarHBondContact O-CB 3.38Å; K400-C403 PolarHBondContact O-N 3.09Å; K400-C403 VanDerWaalsContact O-N 3.13Å; C403-I406 PolarHBondContact O-N 3.31Å; C403-L407 WeakPolarHBondContact O-CB 3.24Å; C403-L407 WeakPolarHBondContact O-CG 3.22Å; C403-L407 PolarHBondContact O-N 3.19Å
404I95.5Very high91.5Very high11 Ų1155.7 Ų55.76%0.05628%0.282CS..Hα-helixtrans-61-47.7177.6-69.1171.2000110.8A391 K400 D401 I406 L407 Q408 L426 V429 L430A391-I404 HydrophobicContact CB-CG1 3.93Å; K400-I404 HydrophobicContact CG-CD1 4.07Å; K400-I404 WeakPolarHBondContact O-CG1 3.48Å; K400-I404 PolarHBondContact O-N 3.21Å; D401-I404 PolarHBondContact O-N 3.25Å; I404-I406 VanDerWaalsContact C-N 3.35Å; I404-I406 PolarHBondContact O-N 2.85Å; I404-L407 PolarHBondContact O-N 3.08Å; I404-Q408 HydrophobicContact CG2-CG 4.33Å; I404-Q408 WeakPolarHBondContact O-CB 3.18Å; I404-Q408 VanDerWaalsContact O-CG 3.31Å; I404-Q408 WeakPolarHBondContact O-CG 3.4Å; I404-Q408 PolarHBondContact O-N 2.99Å; I404-L426 HydrophobicContact CG2-CD2 4.14Å; I404-V429 HydrophobicContact CD1-CG1 4.16Å; I404-L430 HydrophobicContact CD1-CD2 4.37Å; I404-L430 HydrophobicContact CG2-CD2 4.26Å
405E94.9Very high91.1Very high92 Ų9259.5 Ų59.543%0.4329%0.292SS..Hα-helixtrans-57.9-44.6178.1-174-173.1159.900111.8D401 K402 Q408 T409D401-E405 WeakPolarHBondContact O-CB 3.33Å; D401-E405 PolarHBondContact O-N 3.39Å; K402-E405 WeakPolarHBondContact CD-OE2 3.37Å; K402-E405 IonicContact NZ-OE1 2.78Å; K402-E405 IonicContact NZ-OE2 3.34Å; K402-E405 PolarHBondContact NZ-OE2 2.95Å; K402-E405 PolarHBondContact O-N 2.91Å; E405-Q408 PolarHBondContact O-N 3.41Å; E405-T409 WeakPolarHBondContact O-CB 3.4Å; E405-T409 PolarHBondContact O-N 3.38Å; E405-T409 PolarHBondContact O-OG1 3.45Å
406I95.3Very high90.9Very high57 Ų5757.8 Ų57.829%0.29228%0.283SS..Hα-helixtrans-66.8-41.9178.1-66.4165.2000111Y367 L387 K402 C403 I404 T409 T410Y367-I406 HydrophobicContact CE2-CD1 3.87Å; L387-I406 HydrophobicContact CD1-CB 4.18Å; L387-I406 HydrophobicContact CD1-CG2 3.51Å; L387-I406 HydrophobicContact CD2-CD1 4.35Å; K402-I406 WeakPolarHBondContact O-CB 3.39Å; K402-I406 WeakPolarHBondContact O-CD1 3.46Å; K402-I406 WeakPolarHBondContact O-CG1 3.25Å; K402-I406 PolarHBondContact O-N 3.27Å; C403-I406 PolarHBondContact O-N 3.31Å; I404-I406 VanDerWaalsContact C-N 3.35Å; I404-I406 PolarHBondContact O-N 2.85Å; I406-T409 PolarHBondContact O-N 3.35Å; I406-T410 WeakPolarHBondContact O-CB 3.42Å; I406-T410 PolarHBondContact O-N 2.88Å; I406-T410 PolarHBondContact O-OG1 3.42Å
407L95.9Very high91Very high0 Ų058.6 Ų58.60%030%0.303CS..Hα-helixtrans-64.8-43.1177.6-72.5171.2000111.4I384 L387 M388 A391 C403 I404 T410 V411 I422 F425 L426I384-L407 HydrophobicContact CD1-CD2 4.03Å; I384-L407 HydrophobicContact CG2-CD2 4.21Å; L387-L407 HydrophobicContact CB-CD1 4.19Å; L387-L407 HydrophobicContact CB-CD2 3.96Å; L387-L407 HydrophobicContact CB-CG 4Å; L387-L407 HydrophobicContact CD1-CD2 4.3Å; M388-L407 HydrophobicContact CG-CD1 4.03Å; M388-L407 HydrophobicContact CG-CD2 4.06Å; A391-L407 HydrophobicContact CB-CD1 4.23Å; C403-L407 WeakPolarHBondContact O-CB 3.24Å; C403-L407 WeakPolarHBondContact O-CG 3.22Å; C403-L407 PolarHBondContact O-N 3.19Å; I404-L407 PolarHBondContact O-N 3.08Å; L407-T410 WeakPolarHBondContact O-CB 3.33Å; L407-T410 PolarHBondContact O-N 3.29Å; L407-V411 WeakPolarHBondContact O-CG2 3.17Å; L407-V411 PolarHBondContact O-N 3.05Å; L407-I422 HydrophobicContact CB-CG2 3.85Å; L407-I422 HydrophobicContact CD2-CD1 4.46Å; L407-I422 HydrophobicContact CD2-CG1 4.48Å; L407-I422 HydrophobicContact CD2-CG2 3.95Å; L407-I422 HydrophobicContact CG-CG2 4.41Å; L407-F425 HydrophobicContact CD1-CD1 4.36Å; L407-F425 HydrophobicContact CD1-CE1 3.98Å; L407-L426 HydrophobicContact CB-CD1 4.17Å; L407-L426 HydrophobicContact CB-CD2 4.03Å; L407-L426 HydrophobicContact CB-CG 4.4Å; L407-L426 HydrophobicContact CD1-CD2 4.32Å
408Q95.3Very high91.2Very high73 Ų7360.1 Ų60.134%0.34131%0.307SS..Hα-helixtrans-59.7-46.8173.7-74.8173.6-18.500111.5I404 E405 T410 V411 Q412 L426I404-Q408 HydrophobicContact CG2-CG 4.33Å; I404-Q408 WeakPolarHBondContact O-CB 3.18Å; I404-Q408 VanDerWaalsContact O-CG 3.31Å; I404-Q408 WeakPolarHBondContact O-CG 3.4Å; I404-Q408 PolarHBondContact O-N 2.99Å; E405-Q408 PolarHBondContact O-N 3.41Å; Q408-T410 VanDerWaalsContact C-N 3.3Å; Q408-T410 PolarHBondContact O-N 3.3Å; Q408-V411 WeakPolarHBondContact O-CB 3.34Å; Q408-V411 PolarHBondContact O-N 2.96Å; Q408-Q412 WeakPolarHBondContact O-CG 3.31Å; Q408-Q412 PolarHBondContact O-N 3.4Å; Q408-L426 HydrophobicContact CB-CD1 4.49Å; Q408-L426 HydrophobicContact CG-CD1 3.78Å; Q408-L426 HydrophobicContact CG-CD2 4.49Å
409T93.9Very high91.3Very high58 Ų5856.5 Ų56.536%0.35630%0.295SS..Hα-helixtrans-61.5-40177.2-57.80000111.5E405 I406 V411 Q412 N413E405-T409 WeakPolarHBondContact O-CB 3.4Å; E405-T409 PolarHBondContact O-N 3.38Å; E405-T409 PolarHBondContact O-OG1 3.45Å; I406-T409 PolarHBondContact O-N 3.35Å; T409-V411 VanDerWaalsContact C-N 3.32Å; T409-V411 PolarHBondContact O-N 3.06Å; T409-Q412 PolarHBondContact O-N 2.88Å; T409-N413 WeakPolarHBondContact O-CB 3.41Å; T409-N413 VanDerWaalsContact O-CG 3.24Å; T409-N413 PolarHBondContact O-N 3.38Å; T409-N413 PolarHBondContact O-ND2 2.69Å
410T91.9Very high91.3Very high27 Ų2760.9 Ų60.917%0.16631%0.314CS..Hα-helixtrans-60.5-43.6176.4-60.80000111.4I384 I406 L407 Q408 G414 N416 I422I384-T410 HydrophobicContact CD1-CG2 4Å; I406-T410 WeakPolarHBondContact O-CB 3.42Å; I406-T410 PolarHBondContact O-N 2.88Å; I406-T410 PolarHBondContact O-OG1 3.42Å; L407-T410 WeakPolarHBondContact O-CB 3.33Å; L407-T410 PolarHBondContact O-N 3.29Å; Q408-T410 VanDerWaalsContact C-N 3.3Å; Q408-T410 PolarHBondContact O-N 3.3Å; T410-G414 PolarHBondContact O-N 3.12Å; T410-N416 HydrophobicContact CG2-CB 3.68Å; T410-I422 HydrophobicContact CG2-CD1 3.98Å
411V93.1Very high91.4Very high24 Ų2463.9 Ų63.915%0.14533%0.329CS..Hα-helixtrans-63.1-47.9175.51660000111.7L407 Q408 T409 N413 G414 I422 K423 L426L407-V411 WeakPolarHBondContact O-CG2 3.17Å; L407-V411 PolarHBondContact O-N 3.05Å; Q408-V411 WeakPolarHBondContact O-CB 3.34Å; Q408-V411 PolarHBondContact O-N 2.96Å; T409-V411 VanDerWaalsContact C-N 3.32Å; T409-V411 PolarHBondContact O-N 3.06Å; V411-N413 VanDerWaalsContact C-N 3.29Å; V411-N413 PolarHBondContact O-N 3.36Å; V411-G414 PolarHBondContact O-N 3.5Å; V411-G414 VanDerWaalsContact O-N 3.1Å; V411-I422 HydrophobicContact CG2-CB 3.66Å; V411-I422 HydrophobicContact CG2-CG2 3.45Å; V411-I422 VanDerWaalsContact CG2-CG2 3.45Å; V411-K423 HydrophobicContact CB-CG 4.36Å; V411-K423 HydrophobicContact CG1-CD 3.96Å; V411-K423 HydrophobicContact CG1-CG 3.39Å; V411-K423 HydrophobicContact CG2-CG 3.98Å; V411-L426 HydrophobicContact CG2-CD1 4.45Å
412Q91.8Very high91.5Very high151 Ų15162.5 Ų62.571%0.70632%0.321SS*.Hα-helixtrans-60.9-38.3-179.4-73170.5-1.100112.1Q408 T409 G414Q408-Q412 WeakPolarHBondContact O-CG 3.31Å; Q408-Q412 PolarHBondContact O-N 3.4Å; T409-Q412 PolarHBondContact O-N 2.88Å; Q412-G414 PolarHBondContact O-N 3.23Å
413N89.4Confident91.5Very high102 Ų10264.8 Ų64.855%0.54533%0.331SS..Hα-helixtrans-66.9-23.1177.6-73.4-28.6000113.2T409 V411 R415T409-N413 WeakPolarHBondContact O-CB 3.41Å; T409-N413 VanDerWaalsContact O-CG 3.24Å; T409-N413 PolarHBondContact O-N 3.38Å; T409-N413 PolarHBondContact O-ND2 2.69Å; V411-N413 VanDerWaalsContact C-N 3.29Å; V411-N413 PolarHBondContact O-N 3.36Å; N413-R415 WeakPolarHBondContact O-CG 3.42Å; N413-R415 PolarHBondContact O-N 3.48Å
414G83.6Confident91.5Very high54 Ų5472.7 Ų72.756%0.55736%0.361SS*.  trans67.8-2.5173.800000116.3T410 V411 Q412T410-G414 PolarHBondContact O-N 3.12Å; V411-G414 PolarHBondContact O-N 3.5Å; V411-G414 VanDerWaalsContact O-N 3.1Å; Q412-G414 PolarHBondContact O-N 3.23Å
415R80.6Confident91.5Very high234 Ų23473.5 Ų73.588%0.88336%0.364SS*.  trans-84.8-7.9-174.8-65.2177.6-170.3175.71114.3N413N413-R415 WeakPolarHBondContact O-CG 3.42Å; N413-R415 PolarHBondContact O-N 3.48Å
416N81.9Confident91.5Very high32 Ų3269.7 Ų69.717%0.17135%0.347CS..SBendtrans-95.3131.5-178.5-168.3-52.4000110T410 R418 C419T410-N416 HydrophobicContact CG2-CB 3.68Å; N416-R418 PolarHBondContact O-N 3.46Å; N416-R418 VanDerWaalsContact O-N 3.13Å; N416-R418 WeakPolarHBondContact OD1-CB 3.21Å; N416-R418 PolarHBondContact OD1-N 3.16Å; N416-C419 PolarHBondContact O-N 3.22Å; N416-C419 PolarHBondContact O-SG 3.11Å
417S86.4Confident91.3Very high116 Ų11673.4 Ų73.481%0.81136%0.361SS*.THydrogen-bonded Turntrans-60.9-21.4178.849.80000113.5
418R91.1Very high91.1Very high42 Ų4278 Ų7816%0.15839%0.385CS..THydrogen-bonded Turntrans-95.511.8-178.6-60.7178.765.1-167.41.1114.1D381 N385 N416 E420 E421 I422D381-R418 WeakPolarHBondContact OD1-CD 3.29Å; N385-R418 VanDerWaalsContact OD1-CZ 3.29Å; N385-R418 PolarHBondContact OD1-NH1 3.3Å; N385-R418 PolarHBondContact OD1-NH2 3.01Å; N416-R418 PolarHBondContact O-N 3.46Å; N416-R418 VanDerWaalsContact O-N 3.13Å; N416-R418 WeakPolarHBondContact OD1-CB 3.21Å; N416-R418 PolarHBondContact OD1-N 3.16Å; R418-E420 VanDerWaalsContact C-N 3.27Å; R418-E420 PolarHBondContact O-N 3.36Å; R418-E420 VanDerWaalsContact O-N 3.17Å; R418-E421 HydrophobicContact CB-CB 4.49Å; R418-E421 IonicContact CZ-OE1 2.62Å; R418-E421 IonicContact CZ-OE2 2.67Å; R418-E421 IonicContact NE-OE1 3.56Å; R418-E421 IonicContact NE-OE2 3.84Å; R418-E421 PolarHBondContact NE-OE2 3.13Å; R418-E421 VanDerWaalsContact NH2-CD 3.31Å; R418-E421 IonicContact NH2-OE1 2.72Å; R418-E421 PolarHBondContact NH2-OE1 3.08Å; R418-E421 IonicContact NH2-OE2 3.77Å; R418-E421 PolarHBondContact NH2-OE2 2.66Å; R418-E421 WeakPolarHBondContact O-CB 3.43Å; R418-E421 PolarHBondContact O-N 3.39Å; R418-I422 HydrophobicContact CB-CD1 4.36Å; R418-I422 HydrophobicContact CB-CG1 4.49Å; R418-I422 WeakPolarHBondContact O-CG1 3.28Å; R418-I422 PolarHBondContact O-N 3.39Å
419C91.1Very high90.8Very high12 Ų1275.2 Ų75.28%0.08137%0.373CS..Hα-helixtrans-52-41.3-178.1-78.90000113.7N416 I422 K423N416-C419 PolarHBondContact O-N 3.22Å; N416-C419 PolarHBondContact O-SG 3.11Å; C419-I422 PolarHBondContact O-N 3.5Å; C419-K423 WeakPolarHBondContact O-CB 3.49Å; C419-K423 VanDerWaalsContact O-CG 3.28Å; C419-K423 WeakPolarHBondContact O-CG 3.08Å; C419-K423 PolarHBondContact O-N 3Å
420E91.4Very high90.4Very high113 Ų11375.9 Ų75.953%0.52837%0.374SS..Hα-helixtrans-70.8-29.7179.4-68.4-51.8131.800113.8R418 K423 R424R418-E420 VanDerWaalsContact C-N 3.27Å; R418-E420 PolarHBondContact O-N 3.36Å; R418-E420 VanDerWaalsContact O-N 3.17Å; E420-K423 IonicContact OE1-NZ 2.65Å; E420-K423 PolarHBondContact OE1-NZ 3.49Å; E420-R424 WeakPolarHBondContact O-CG 3.27Å; E420-R424 PolarHBondContact O-N 3.01Å; E420-R424 PolarHBondContact O-NE 3.34Å
421E94.8Very high89.7Confident69 Ų6981.5 Ų81.532%0.32240%0.396SS..Hα-helixtrans-69.7-48.6171.4-173.5-166.9158.400110.5R418 K423 R424 F425R418-E421 HydrophobicContact CB-CB 4.49Å; R418-E421 IonicContact CZ-OE1 2.62Å; R418-E421 IonicContact CZ-OE2 2.67Å; R418-E421 IonicContact NE-OE1 3.56Å; R418-E421 IonicContact NE-OE2 3.84Å; R418-E421 PolarHBondContact NE-OE2 3.13Å; R418-E421 VanDerWaalsContact NH2-CD 3.31Å; R418-E421 IonicContact NH2-OE1 2.72Å; R418-E421 PolarHBondContact NH2-OE1 3.08Å; R418-E421 IonicContact NH2-OE2 3.77Å; R418-E421 PolarHBondContact NH2-OE2 2.66Å; R418-E421 WeakPolarHBondContact O-CB 3.43Å; R418-E421 PolarHBondContact O-N 3.39Å; E421-K423 VanDerWaalsContact C-N 3.32Å; E421-K423 PolarHBondContact O-N 3.07Å; E421-R424 PolarHBondContact O-N 3.35Å; E421-R424 VanDerWaalsContact O-N 3.17Å; E421-F425 WeakPolarHBondContact O-CB 3.5Å; E421-F425 PolarHBondContact O-N 3.17Å
422I94.5Very high88Confident0 Ų086.6 Ų86.60%042%0.419CS..Hα-helixtrans-61.3-41.7-179.9-60.5165.8000110.5I384 L407 T410 V411 R418 C419 R424 F425 L426I384-I422 HydrophobicContact CD1-CD1 4.19Å; I384-I422 HydrophobicContact CG2-CD1 3.95Å; I384-I422 HydrophobicContact CG2-CG1 4.15Å; L407-I422 HydrophobicContact CB-CG2 3.85Å; L407-I422 HydrophobicContact CD2-CD1 4.46Å; L407-I422 HydrophobicContact CD2-CG1 4.48Å; L407-I422 HydrophobicContact CD2-CG2 3.95Å; L407-I422 HydrophobicContact CG-CG2 4.41Å; T410-I422 HydrophobicContact CG2-CD1 3.98Å; V411-I422 HydrophobicContact CG2-CB 3.66Å; V411-I422 HydrophobicContact CG2-CG2 3.45Å; V411-I422 VanDerWaalsContact CG2-CG2 3.45Å; R418-I422 HydrophobicContact CB-CD1 4.36Å; R418-I422 HydrophobicContact CB-CG1 4.49Å; R418-I422 WeakPolarHBondContact O-CG1 3.28Å; R418-I422 PolarHBondContact O-N 3.39Å; C419-I422 PolarHBondContact O-N 3.5Å; I422-R424 PolarHBondContact O-N 3.04Å; I422-F425 PolarHBondContact O-N 3.32Å; I422-L426 HydrophobicContact CG2-CD1 3.84Å; I422-L426 HydrophobicContact CG2-CG 4.16Å; I422-L426 WeakPolarHBondContact O-CB 3.49Å; I422-L426 VanDerWaalsContact O-CG 3.3Å; I422-L426 WeakPolarHBondContact O-CG 3.48Å; I422-L426 PolarHBondContact O-N 3.01Å
423K94.2Very high86.3Confident93 Ų9386 Ų8640%0.40442%0.416SS..Hα-helixtrans-56.8-48.1174.4-79.5174.1-172.5174.60112.3V411 C419 E420 E421 K427V411-K423 HydrophobicContact CB-CG 4.36Å; V411-K423 HydrophobicContact CG1-CD 3.96Å; V411-K423 HydrophobicContact CG1-CG 3.39Å; V411-K423 HydrophobicContact CG2-CG 3.98Å; C419-K423 WeakPolarHBondContact O-CB 3.49Å; C419-K423 VanDerWaalsContact O-CG 3.28Å; C419-K423 WeakPolarHBondContact O-CG 3.08Å; C419-K423 PolarHBondContact O-N 3Å; E420-K423 IonicContact OE1-NZ 2.65Å; E420-K423 PolarHBondContact OE1-NZ 3.49Å; E421-K423 VanDerWaalsContact C-N 3.32Å; E421-K423 PolarHBondContact O-N 3.07Å; K423-K427 PolarHBondContact O-N 3.26Å; K423-K427 VanDerWaalsContact O-N 3.09Å
424R94.4Very high86.1Confident166 Ų16685.3 Ų85.363%0.62641%0.41SS*.Hα-helixtrans-64-43.8179.1-75.1-177.8-69.1146.4-3.5111.3E420 E421 I422 K427 N428E420-R424 WeakPolarHBondContact O-CG 3.27Å; E420-R424 PolarHBondContact O-N 3.01Å; E420-R424 PolarHBondContact O-NE 3.34Å; E421-R424 PolarHBondContact O-N 3.35Å; E421-R424 VanDerWaalsContact O-N 3.17Å; I422-R424 PolarHBondContact O-N 3.04Å; R424-K427 PolarHBondContact O-N 3.15Å; R424-N428 PolarHBondContact O-N 3.18Å
425F95.6Very high86.2Confident28 Ų2886.9 Ų86.912%0.12340%0.402CS..Hα-helixtrans-59.2-51.9176171-96.5000112.2M388 A391 E392 L407 E421 I422 K427 N428 V429M388-F425 HydrophobicContact CB-CD1 4.49Å; M388-F425 HydrophobicContact CB-CE1 4.06Å; M388-F425 HydrophobicContact CB-CE2 4.21Å; M388-F425 HydrophobicContact CB-CZ 3.9Å; M388-F425 HydrophobicContact CE-CB 3.73Å; M388-F425 HydrophobicContact CE-CD1 4.11Å; M388-F425 HydrophobicContact CE-CD2 3.67Å; M388-F425 HydrophobicContact CE-CE2 4.32Å; M388-F425 HydrophobicContact CE-CG 3.55Å; M388-F425 HydrophobicContact CG-CD1 4.02Å; M388-F425 HydrophobicContact CG-CE1 3.98Å; M388-F425 HydrophobicContact CG-CG 4.4Å; M388-F425 HydrophobicContact CG-CZ 4.32Å; M388-F425 VanDerWaalsContact O-CZ 3.22Å; M388-F425 WeakPolarHBondContact O-CZ 3.34Å; A391-F425 HydrophobicContact CB-CE1 3.8Å; A391-F425 HydrophobicContact CB-CZ 3.92Å; E392-F425 HydrophobicContact CB-CE2 4.12Å; E392-F425 HydrophobicContact CB-CZ 4.14Å; L407-F425 HydrophobicContact CD1-CD1 4.36Å; L407-F425 HydrophobicContact CD1-CE1 3.98Å; E421-F425 WeakPolarHBondContact O-CB 3.5Å; E421-F425 PolarHBondContact O-N 3.17Å; I422-F425 PolarHBondContact O-N 3.32Å; F425-K427 VanDerWaalsContact C-N 3.25Å; F425-K427 PolarHBondContact O-N 3Å; F425-N428 WeakPolarHBondContact O-CB 3.42Å; F425-N428 PolarHBondContact O-N 3.05Å; F425-V429 HydrophobicContact CD1-CG2 4.27Å; F425-V429 HydrophobicContact CD2-CG2 4.27Å; F425-V429 HydrophobicContact CE1-CG2 3.72Å; F425-V429 HydrophobicContact CE2-CG2 3.73Å; F425-V429 HydrophobicContact CZ-CG2 3.41Å; F425-V429 VanDerWaalsContact CZ-CG2 3.41Å; F425-V429 PolarHBondContact O-N 3.1Å
426L94.3Very high86.5Confident12 Ų1278.7 Ų78.76%0.06338%0.375CS..Hα-helixtrans-59.1-37.5179.3-73.5172.1000112I404 L407 Q408 V411 I422 N428 V429 L430I404-L426 HydrophobicContact CG2-CD2 4.14Å; L407-L426 HydrophobicContact CB-CD1 4.17Å; L407-L426 HydrophobicContact CB-CD2 4.03Å; L407-L426 HydrophobicContact CB-CG 4.4Å; L407-L426 HydrophobicContact CD1-CD2 4.32Å; Q408-L426 HydrophobicContact CB-CD1 4.49Å; Q408-L426 HydrophobicContact CG-CD1 3.78Å; Q408-L426 HydrophobicContact CG-CD2 4.49Å; V411-L426 HydrophobicContact CG2-CD1 4.45Å; I422-L426 HydrophobicContact CG2-CD1 3.84Å; I422-L426 HydrophobicContact CG2-CG 4.16Å; I422-L426 WeakPolarHBondContact O-CB 3.49Å; I422-L426 VanDerWaalsContact O-CG 3.3Å; I422-L426 WeakPolarHBondContact O-CG 3.48Å; I422-L426 PolarHBondContact O-N 3.01Å; L426-N428 PolarHBondContact O-N 3.47Å; L426-V429 PolarHBondContact O-N 3.39Å; L426-L430 VanDerWaalsContact O-CB 3.3Å; L426-L430 WeakPolarHBondContact O-CB 3.48Å; L426-L430 VanDerWaalsContact O-CG 3.23Å; L426-L430 WeakPolarHBondContact O-CG 3.49Å; L426-L430 PolarHBondContact O-N 3.15Å
427K92.4Very high86.8Confident135 Ų13581.5 Ų81.559%0.58739%0.387SS*.Hα-helixtrans-63-30176.1-168176.9-175.1177.70112.7K423 R424 F425 K431K423-K427 PolarHBondContact O-N 3.26Å; K423-K427 VanDerWaalsContact O-N 3.09Å; R424-K427 PolarHBondContact O-N 3.15Å; F425-K427 VanDerWaalsContact C-N 3.25Å; F425-K427 PolarHBondContact O-N 3Å; K427-K431 VanDerWaalsContact O-CD 3.31Å; K427-K431 WeakPolarHBondContact O-CD 3.48Å; K427-K431 WeakPolarHBondContact O-CG 3.45Å
428N90.5Very high86.8Confident97 Ų9779.3 Ų79.352%0.51936%0.361SS..Hα-helixtrans-79.7-49.1177.1-66.3-13.3000110.7R424 F425 L426 L430 K431 E432R424-N428 PolarHBondContact O-N 3.18Å; F425-N428 WeakPolarHBondContact O-CB 3.42Å; F425-N428 PolarHBondContact O-N 3.05Å; L426-N428 PolarHBondContact O-N 3.47Å; N428-L430 VanDerWaalsContact C-N 3.32Å; N428-L430 PolarHBondContact O-N 3.09Å; N428-K431 PolarHBondContact O-N 3.23Å; N428-K431 VanDerWaalsContact O-N 3.14Å; N428-E432 PolarHBondContact O-N 2.94Å
429V89.1Confident86.6Confident14 Ų1481.8 Ų81.89%0.08537%0.374CS..Hα-helixtrans-59.8-41.5-179.4174.30000112A391 I404 F425 L426 K431 E432A391-V429 VanDerWaalsContact O-CG1 3.29Å; A391-V429 WeakPolarHBondContact O-CG1 3.27Å; I404-V429 HydrophobicContact CD1-CG1 4.16Å; F425-V429 HydrophobicContact CD1-CG2 4.27Å; F425-V429 HydrophobicContact CD2-CG2 4.27Å; F425-V429 HydrophobicContact CE1-CG2 3.72Å; F425-V429 HydrophobicContact CE2-CG2 3.73Å; F425-V429 HydrophobicContact CZ-CG2 3.41Å; F425-V429 VanDerWaalsContact CZ-CG2 3.41Å; F425-V429 PolarHBondContact O-N 3.1Å; L426-V429 PolarHBondContact O-N 3.39Å; V429-K431 VanDerWaalsContact C-N 3.3Å; V429-K431 PolarHBondContact O-N 3.18Å; V429-E432 PolarHBondContact O-N 2.75Å
430L86.4Confident86.2Confident73 Ų7386.8 Ų86.838%0.38240%0.395SS..THydrogen-bonded Turntrans-78.3-9.8-178.8-64.6172.8000114.1I404 L426 N428I404-L430 HydrophobicContact CD1-CD2 4.37Å; I404-L430 HydrophobicContact CG2-CD2 4.26Å; L426-L430 VanDerWaalsContact O-CB 3.3Å; L426-L430 WeakPolarHBondContact O-CB 3.48Å; L426-L430 VanDerWaalsContact O-CG 3.23Å; L426-L430 WeakPolarHBondContact O-CG 3.49Å; L426-L430 PolarHBondContact O-N 3.15Å; N428-L430 VanDerWaalsContact C-N 3.32Å; N428-L430 PolarHBondContact O-N 3.09Å
431K77.1Confident85.8Confident144 Ų14484.8 Ų84.863%0.62639%0.385SS*.THydrogen-bonded Turntrans-86.6-18.5172.4-82.8177176.7-1690112.7K427 N428 V429K427-K431 VanDerWaalsContact O-CD 3.31Å; K427-K431 WeakPolarHBondContact O-CD 3.48Å; K427-K431 WeakPolarHBondContact O-CG 3.45Å; N428-K431 PolarHBondContact O-N 3.23Å; N428-K431 VanDerWaalsContact O-N 3.14Å; V429-K431 VanDerWaalsContact C-N 3.3Å; V429-K431 PolarHBondContact O-N 3.18Å
432E57.9Low85.1Confident132 Ų13286.1 Ų86.162%0.61739%0.39SS*.  trans-95.8-2.6-179.1-66-173.2-168.300113K394 N428 V429K394-E432 VanDerWaalsContact CE-OE2 3.23Å; K394-E432 WeakPolarHBondContact CE-OE2 3.46Å; K394-E432 IonicContact NZ-OE2 3.69Å; N428-E432 PolarHBondContact O-N 2.94Å; V429-E432 PolarHBondContact O-N 2.75Å
433E54.5Low84.2Confident139 Ų13993.9 Ų93.965%0.6543%0.426SS*.  trans-92.80169.4-66.9-173.4157.800110.7K400K400-E433 VanDerWaalsContact CE-OE1 3.22Å; K400-E433 WeakPolarHBondContact CE-OE1 3.41Å; K400-E433 IonicContact NZ-OE1 3.74Å; K400-E433 PolarHBondContact NZ-OE1 3.39Å

Retrieved 433 of 433 residues in 834.3 ms (Link to these results)

U.S. Privacy Notice - Disclaimer / Registrations / Copyright Statement - Linking Policy - Notice of Privacy Practices (HIPAA) - Notice of Non‑Discrimination
© Copyright 2026 St. Jude Children's Research Hospital, a not-for-profit, section 501(c)(3).