A0A068WAZ7_MOUSE Loading...

Protein 4.1

AlphaFold DB , UniProt , Accession A0A068WAZ7, Species MOUSE (Mus musculus, Mouse), Gene Epb41, Length 615 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M88.6Confident94.2Very high79 Ų7943.5 Ų43.539%0.38923%0.228SC..  0127.20-63.5-61.9-80.400107.6V16 V17 V69 W71M1-V16 WeakPolarHBondContact O-CA 3.39Å; M1-V17 HydrophobicContact CB-CG2 4.28Å; M1-V17 PolarHBondContact N-O 2.78Å; M1-V17 PolarHBondContact O-N 2.93Å; M1-V69 HydrophobicContact CE-CG1 3.6Å; M1-W71 HydrophobicContact CB-CE3 4.05Å; M1-W71 HydrophobicContact CB-CH2 3.73Å; M1-W71 HydrophobicContact CB-CZ2 4.42Å; M1-W71 HydrophobicContact CB-CZ3 3.52Å; M1-W71 HydrophobicContact CE-CH2 3.78Å; M1-W71 HydrophobicContact CE-CZ2 3.42Å; M1-W71 VanDerWaalsContact CE-CZ2 3.42Å; M1-W71 HydrophobicContact CG-CH2 3.65Å; M1-W71 HydrophobicContact CG-CZ2 4.3Å; M1-W71 HydrophobicContact CG-CZ3 3.96Å
2H92.9Very high94.3Very high79 Ų7945.4 Ų45.437%0.36624%0.243SC..EExtended strand (participates in β ladder)trans-77.2128.9-177-164.4-84.7000111E14 P70 W71H2-E14 IonicContact CE1-OE2 2.94Å; H2-E14 IonicContact NE2-OE2 3.37Å; H2-P70 HydrophobicContact CB-CB 4.48Å; H2-W71 PolarHBondContact O-N 3.31Å; H2-W71 VanDerWaalsContact O-N 3.07Å
3C95.8Very high94.5Very high0 Ų045.3 Ų45.30%024%0.237CC..EExtended strand (participates in β ladder)trans-119.5139.7177.3-65.40000109.6E14 C15 V17 L26 W71C3-E14 WeakPolarHBondContact O-CA 3.36Å; C3-C15 PolarHBondContact N-O 3.39Å; C3-C15 PolarHBondContact O-N 2.91Å; C3-V17 VanDerWaalsContact SG-CG2 3.52Å; C3-L26 HydrophobicContact CB-CD1 4.04Å; C3-L26 HydrophobicContact CB-CD2 4.27Å; C3-W71 CarbonylContact C-O 3.58Å; C3-W71 WeakPolarHBondContact CA-O 3.47Å
4K96.5Very high94.7Very high70 Ų7049.2 Ų49.230%0.30425%0.254SS..EExtended strand (participates in β ladder)trans-124.4124.4173.1-179.2179.4-174.6101.60108.2V12 E14 W71 N72 F73K4-V12 HydrophobicContact CD-CG1 4.11Å; K4-V12 HydrophobicContact CG-CG1 3.46Å; K4-V12 VanDerWaalsContact CG-CG1 3.46Å; K4-E14 HydrophobicContact CB-CG 4.45Å; K4-E14 HydrophobicContact CG-CG 4.18Å; K4-E14 IonicContact NZ-OE1 3.54Å; K4-E14 PolarHBondContact NZ-OE1 3.35Å; K4-W71 PolarHBondContact N-O 3.1Å; K4-N72 WeakPolarHBondContact CB-OD1 3.36Å; K4-N72 CarbonylContact O-C 3.51Å; K4-N72 WeakPolarHBondContact O-CA 3.41Å; K4-F73 PolarHBondContact O-N 2.82Å
5V97.6Very high94.7Very high0 Ų046.8 Ų46.80%024%0.243CC..EExtended strand (participates in β ladder)trans-120.7115-178.7-171.50000108.7L7 V12 Y13 L26 V30 L44 F73 F75V5-L7 HydrophobicContact CG1-CD2 4Å; V5-V12 WeakPolarHBondContact O-CA 3.14Å; V5-Y13 PolarHBondContact N-O 3.12Å; V5-Y13 PolarHBondContact O-N 3.4Å; V5-L26 HydrophobicContact CG2-CD1 4.37Å; V5-V30 HydrophobicContact CB-CG2 4.31Å; V5-V30 HydrophobicContact CG1-CG2 4.17Å; V5-V30 HydrophobicContact CG2-CG2 3.95Å; V5-L44 HydrophobicContact CG1-CD2 3.72Å; V5-F73 CarbonylContact C-O 3.57Å; V5-F73 WeakPolarHBondContact CA-O 3.5Å; V5-F73 HydrophobicContact CG1-CB 4.44Å; V5-F73 HydrophobicContact CG2-CB 4.33Å; V5-F73 HydrophobicContact CG2-CD2 4.44Å; V5-F75 HydrophobicContact CG1-CB 4.02Å
6S96.8Very high94.7Very high52 Ų5249.7 Ų49.736%0.36426%0.263SS..EExtended strand (participates in β ladder)trans-77.3125.5168.8-56.20000109.2F73 T74 F75S6-F73 PolarHBondContact N-O 3.32Å; S6-T74 CarbonylContact O-C 3.58Å; S6-T74 WeakPolarHBondContact O-CA 3.3Å; S6-F75 PolarHBondContact O-N 3.48Å
7L96.9Very high94.7Very high6 Ų646.9 Ų46.93%0.03125%0.248CC..  trans-92172-177.4-58.1-180000111V5 D9 D10 T11 V30 L34 F75V5-L7 HydrophobicContact CG1-CD2 4Å; L7-D9 VanDerWaalsContact C-N 3.25Å; L7-D9 WeakPolarHBondContact CB-OD1 2.77Å; L7-D9 PolarHBondContact O-N 2.85Å; L7-D10 PolarHBondContact O-N 3.45Å; L7-T11 WeakPolarHBondContact CD1-OG1 3.3Å; L7-T11 PolarHBondContact N-O 3.49Å; L7-V30 HydrophobicContact CD2-CG1 3.78Å; L7-L34 HydrophobicContact CD1-CD2 3.6Å; L7-L34 HydrophobicContact CD1-CG 4.46Å; L7-L34 HydrophobicContact CD2-CD1 4.26Å; L7-F75 HydrophobicContact CD2-CB 3.8Å; L7-F75 HydrophobicContact CD2-CG 4.28Å
8L95.4Very high94.7Very high5 Ų552.3 Ų52.33%0.02627%0.272CS..THydrogen-bonded Turntrans-74.5-17.5-176.2-72.5173.2000113.6D10 F42 F75 V77 Y95 L98 Q99 Q102L8-D10 VanDerWaalsContact C-N 3.28Å; L8-F42 HydrophobicContact CD1-CE1 4.47Å; L8-F75 HydrophobicContact CD1-CD1 4.25Å; L8-F75 HydrophobicContact CD1-CE1 4.49Å; L8-F75 WeakPolarHBondContact CD2-O 3.48Å; L8-F75 HydrophobicContact CG-CD1 4.3Å; L8-F75 WeakPolarHBondContact CG-O 3.37Å; L8-V77 HydrophobicContact CD1-CG2 4.3Å; L8-Y95 HydrophobicContact CB-CD1 3.94Å; L8-Y95 HydrophobicContact CB-CE1 4.3Å; L8-Y95 HydrophobicContact CD1-CD1 3.99Å; L8-Y95 WeakPolarHBondContact CD1-O 3.29Å; L8-Y95 HydrophobicContact CG-CD1 4.44Å; L8-L98 HydrophobicContact CB-CB 3.94Å; L8-L98 HydrophobicContact CB-CD1 4.18Å; L8-Q99 HydrophobicContact CD1-CB 4.11Å; L8-Q99 HydrophobicContact CD2-CB 4.2Å; L8-Q102 PolarHBondContact O-NE2 2.98Å
9D91.5Very high94.4Very high19 Ų1956.8 Ų56.810%0.10229%0.289CS..THydrogen-bonded Turntrans-93.818.1177.670.9-15.8000112.2L7 T11 L98 T325L7-D9 VanDerWaalsContact C-N 3.25Å; L7-D9 WeakPolarHBondContact CB-OD1 2.77Å; L7-D9 PolarHBondContact O-N 2.85Å; D9-T11 VanDerWaalsContact CG-OG1 3.28Å; D9-T11 PolarHBondContact O-N 3.38Å; D9-T11 VanDerWaalsContact OD1-CB 3.3Å; D9-T11 WeakPolarHBondContact OD1-CB 3.45Å; D9-T11 WeakPolarHBondContact OD1-CG2 3.44Å; D9-T11 PolarHBondContact OD1-N 3.21Å; D9-T11 PolarHBondContact OD1-OG1 3.11Å; D9-T11 VanDerWaalsContact OD2-CG2 3.23Å; D9-T11 WeakPolarHBondContact OD2-CG2 3.41Å; D9-T11 PolarHBondContact OD2-OG1 3.1Å; D9-L98 HydrophobicContact CB-CD1 3.89Å; D9-T325 WeakPolarHBondContact CB-OG1 3.21Å
10D90.7Very high94.4Very high132 Ų13259.6 Ų59.671%0.70630%0.301SS*.SBendtrans58.89.1-175.3-60.8-38.1000114.9L7 L8L7-D10 PolarHBondContact O-N 3.45Å; L8-D10 VanDerWaalsContact C-N 3.28Å
11T93.6Very high94.5Very high36 Ų3657.1 Ų57.122%0.22129%0.289CS..  trans-75.7165.9167.369.30000110.7L7 D9L7-T11 WeakPolarHBondContact CD1-OG1 3.3Å; L7-T11 PolarHBondContact N-O 3.49Å; D9-T11 VanDerWaalsContact CG-OG1 3.28Å; D9-T11 PolarHBondContact O-N 3.38Å; D9-T11 VanDerWaalsContact OD1-CB 3.3Å; D9-T11 WeakPolarHBondContact OD1-CB 3.45Å; D9-T11 WeakPolarHBondContact OD1-CG2 3.44Å; D9-T11 PolarHBondContact OD1-N 3.21Å; D9-T11 PolarHBondContact OD1-OG1 3.11Å; D9-T11 VanDerWaalsContact OD2-CG2 3.23Å; D9-T11 WeakPolarHBondContact OD2-CG2 3.41Å; D9-T11 PolarHBondContact OD2-OG1 3.1Å
12V95.9Very high94.8Very high67 Ų6758.3 Ų58.341%0.40629%0.292SS..EExtended strand (participates in β ladder)trans-123.6123.9176.2178.10000108.4K4 V5 E14K4-V12 HydrophobicContact CD-CG1 4.11Å; K4-V12 HydrophobicContact CG-CG1 3.46Å; K4-V12 VanDerWaalsContact CG-CG1 3.46Å; V5-V12 WeakPolarHBondContact O-CA 3.14Å; V12-E14 HydrophobicContact CG1-CG 3.8Å
13Y96.6Very high94.9Very high44 Ų4454.6 Ų54.617%0.17328%0.275CS..EExtended strand (participates in β ladder)trans-97120.4170.1178.4-109.1000110.2V5 C15 V30 H33V5-Y13 PolarHBondContact N-O 3.12Å; V5-Y13 PolarHBondContact O-N 3.4Å; Y13-C15 HydrophobicContact CE1-CB 3.73Å; Y13-V30 HydrophobicContact CD1-CG2 3.85Å; Y13-V30 HydrophobicContact CE1-CG2 4.16Å; Y13-H33 HydrophobicContact CD2-CB 3.99Å; Y13-H33 AromaticContact CD2-CD2 3.27Å; Y13-H33 WeakPolarHBondContact CD2-CD2 3.46Å; Y13-H33 AromaticContact CD2-CE1 3.9Å; Y13-H33 AromaticContact CD2-CG 3.42Å; Y13-H33 VanDerWaalsContact CD2-CG 3.42Å; Y13-H33 AromaticContact CD2-ND1 3.82Å; Y13-H33 AromaticContact CD2-NE2 3.57Å; Y13-H33 HydrophobicContact CE2-CB 3.66Å; Y13-H33 AromaticContact CE2-CD2 3.84Å; Y13-H33 AromaticContact CE2-CG 3.46Å; Y13-H33 VanDerWaalsContact CE2-CG 3.46Å; Y13-H33 AromaticContact CE2-ND1 3.76Å; Y13-H33 AromaticContact CG-CD2 3.81Å
14E96.8Very high94.9Very high100 Ų10057.7 Ų57.747%0.46729%0.29SS..EExtended strand (participates in β ladder)trans-112.3131.5177.7-59.1-166.8164.800110.4H2 C3 K4 V12H2-E14 IonicContact CE1-OE2 2.94Å; H2-E14 IonicContact NE2-OE2 3.37Å; C3-E14 WeakPolarHBondContact O-CA 3.36Å; K4-E14 HydrophobicContact CB-CG 4.45Å; K4-E14 HydrophobicContact CG-CG 4.18Å; K4-E14 IonicContact NZ-OE1 3.54Å; K4-E14 PolarHBondContact NZ-OE1 3.35Å; V12-E14 HydrophobicContact CG1-CG 3.8Å
15C95.6Very high94.9Very high13 Ų1357.9 Ų57.99%0.08829%0.294CS..EExtended strand (participates in β ladder)trans-150.9165.1179.572.10000112.5C3 Y13 L26C3-C15 PolarHBondContact N-O 3.39Å; C3-C15 PolarHBondContact O-N 2.91Å; Y13-C15 HydrophobicContact CE1-CB 3.73Å; C15-L26 VanDerWaalsContact SG-CD1 3.52Å
16V94.9Very high94.9Very high93 Ų9357.9 Ų57.956%0.56429%0.294SS*.EExtended strand (participates in β ladder)trans-111.5117.8176.1-177.20000110.1M1 R29M1-V16 WeakPolarHBondContact O-CA 3.39Å; V16-R29 PolarHBondContact O-NH1 3Å
17V94.3Very high94.9Very high3 Ų355.9 Ų55.92%0.01828%0.28CS..  trans-102.3158.2175.8-58.40000111.9M1 C3 A21 L26 I62 W71M1-V17 HydrophobicContact CB-CG2 4.28Å; M1-V17 PolarHBondContact N-O 2.78Å; M1-V17 PolarHBondContact O-N 2.93Å; C3-V17 VanDerWaalsContact SG-CG2 3.52Å; V17-A21 HydrophobicContact CB-CB 3.81Å; V17-A21 HydrophobicContact CG2-CB 4.01Å; V17-L26 HydrophobicContact CG1-CB 4.42Å; V17-L26 HydrophobicContact CG1-CD1 3.92Å; V17-I62 HydrophobicContact CG2-CD1 4.31Å; V17-W71 HydrophobicContact CG2-CE3 4.42Å; V17-W71 HydrophobicContact CG2-CZ3 4.01Å
18E93.7Very high94.9Very high143 Ų14360.6 Ų60.667%0.66830%0.3SS*.  trans-62.8155.3175.4-64.5-175.2-17700112.3H20 A21E18-H20 PolarHBondContact O-N 3.37Å; E18-H20 VanDerWaalsContact O-N 3.11Å; E18-A21 HydrophobicContact CB-CB 4.4Å; E18-A21 VanDerWaalsContact O-CB 3.28Å; E18-A21 WeakPolarHBondContact O-CB 3.45Å; E18-A21 PolarHBondContact O-N 3.26Å; E18-A21 VanDerWaalsContact O-N 3.08Å
19K90.1Very high95Very high139 Ų13964.4 Ų64.460%0.60431%0.314SS*.THydrogen-bonded Turntrans-58.2-27.7-179.9-176.5179.3-178.7179.70113.3K63K19-K63 HydrophobicContact CG-CD 4.44Å; K19-K63 VanDerWaalsContact O-CD 3.29Å; K19-K63 WeakPolarHBondContact O-CD 3.38Å; K19-K63 WeakPolarHBondContact O-CE 3.48Å
20H94.3Very high95.3Very high111 Ų11163.5 Ų63.551%0.51431%0.309SS..THydrogen-bonded Turntrans-109.412.2-178.4-65.7-94.2000112.9E18 K22 E61 K63E18-H20 PolarHBondContact O-N 3.37Å; E18-H20 VanDerWaalsContact O-N 3.11Å; H20-K22 PolarHBondContact O-N 2.96Å; H20-E61 IonicContact ND1-OE2 2.96Å; H20-K63 PolarHBondContact CE1-NZ 2.77Å; H20-K63 PolarHBondContact ND1-NZ 2.82Å; H20-K63 VanDerWaalsContact ND1-NZ 3.12Å; H20-K63 PolarHBondContact NE2-NZ 3.24Å
21A96.1Very high95.6Very high8 Ų857.3 Ų57.37%0.06628%0.276CS..  trans-57.4136.7176.200000111.2V17 E18 D25 E61 I62V17-A21 HydrophobicContact CB-CB 3.81Å; V17-A21 HydrophobicContact CG2-CB 4.01Å; E18-A21 HydrophobicContact CB-CB 4.4Å; E18-A21 VanDerWaalsContact O-CB 3.28Å; E18-A21 WeakPolarHBondContact O-CB 3.45Å; E18-A21 PolarHBondContact O-N 3.26Å; E18-A21 VanDerWaalsContact O-N 3.08Å; A21-D25 WeakPolarHBondContact CA-OD2 3.49Å; A21-D25 HydrophobicContact CB-CB 4.33Å; A21-E61 WeakPolarHBondContact O-CA 3.5Å; A21-I62 HydrophobicContact CB-CD1 4.39Å; A21-I62 PolarHBondContact O-N 2.9Å
22K96.1Very high95.7Very high104 Ų10461 Ų6145%0.45229%0.291SS..BIsolated β-bridgetrans-84.7164.4172.5-65.1178.3-179.7173.30110.6H20 Q24 D25 K60H20-K22 PolarHBondContact O-N 2.96Å; K22-Q24 PolarHBondContact O-N 3.09Å; K22-D25 PolarHBondContact N-OD2 3.03Å; K22-D25 PolarHBondContact O-N 3.41Å; K22-D25 VanDerWaalsContact O-N 3.12Å; K22-K60 CarbonylContact C-O 3.52Å; K22-K60 VanDerWaalsContact CA-O 3.3Å; K22-K60 WeakPolarHBondContact CA-O 3.17Å
23G95.1Very high95.7Very high1 Ų162.8 Ų62.81%0.0129%0.294CS..Hα-helixtrans-56.5-38175.500000113.1D25 L26 L27 S58 K60G23-D25 VanDerWaalsContact C-N 3.3Å; G23-D25 PolarHBondContact O-N 3.47Å; G23-L26 PolarHBondContact O-N 3.12Å; G23-L27 PolarHBondContact O-N 3.44Å; G23-S58 PolarHBondContact N-O 3.36Å; G23-K60 PolarHBondContact N-O 2.96Å
24Q95.4Very high95.6Very high65 Ų6561.3 Ų61.330%0.30429%0.289SS..Hα-helixtrans-59.6-39.1176.5-169.173.124.500112K22 L26 L27 K28 S58K22-Q24 PolarHBondContact O-N 3.09Å; Q24-L26 VanDerWaalsContact C-N 3.32Å; Q24-L26 PolarHBondContact O-N 3.07Å; Q24-L27 PolarHBondContact O-N 3.11Å; Q24-K28 VanDerWaalsContact O-CB 3.32Å; Q24-K28 WeakPolarHBondContact O-CB 3.47Å; Q24-K28 PolarHBondContact O-N 3.08Å; Q24-S58 PolarHBondContact N-O 2.72Å; Q24-S58 VanDerWaalsContact OE1-CB 3.29Å
25D96.1Very high95.5Very high74 Ų7459.9 Ų59.940%0.39629%0.285SS..Hα-helixtrans-65.3-38.2-176.9-53-34.6000111.2A21 K22 G23 R29A21-D25 WeakPolarHBondContact CA-OD2 3.49Å; A21-D25 HydrophobicContact CB-CB 4.33Å; K22-D25 PolarHBondContact N-OD2 3.03Å; K22-D25 PolarHBondContact O-N 3.41Å; K22-D25 VanDerWaalsContact O-N 3.12Å; G23-D25 VanDerWaalsContact C-N 3.3Å; G23-D25 PolarHBondContact O-N 3.47Å; D25-R29 WeakPolarHBondContact O-CG 3.49Å; D25-R29 PolarHBondContact O-N 2.99Å
26L97.3Very high95.5Very high0 Ų059.5 Ų59.50%028%0.282CS..Hα-helixtrans-72.8-44.1175.1178.961.3000111.5C3 V5 C15 V17 G23 Q24 K28 R29 V30 L44 I62 F73C3-L26 HydrophobicContact CB-CD1 4.04Å; C3-L26 HydrophobicContact CB-CD2 4.27Å; V5-L26 HydrophobicContact CG2-CD1 4.37Å; C15-L26 VanDerWaalsContact SG-CD1 3.52Å; V17-L26 HydrophobicContact CG1-CB 4.42Å; V17-L26 HydrophobicContact CG1-CD1 3.92Å; G23-L26 PolarHBondContact O-N 3.12Å; Q24-L26 VanDerWaalsContact C-N 3.32Å; Q24-L26 PolarHBondContact O-N 3.07Å; L26-K28 VanDerWaalsContact C-N 3.31Å; L26-K28 PolarHBondContact O-N 2.78Å; L26-R29 PolarHBondContact O-N 3.37Å; L26-V30 WeakPolarHBondContact O-CG2 3.47Å; L26-V30 PolarHBondContact O-N 2.75Å; L26-V30 VanDerWaalsContact O-N 3.09Å; L26-L44 HydrophobicContact CB-CD1 4.08Å; L26-L44 HydrophobicContact CD2-CD1 3.7Å; L26-L44 HydrophobicContact CG-CD1 3.6Å; L26-I62 HydrophobicContact CB-CD1 3.75Å; L26-I62 HydrophobicContact CD2-CD1 4.01Å; L26-F73 HydrophobicContact CD2-CD2 3.62Å; L26-F73 HydrophobicContact CD2-CE2 3.52Å; L26-F73 HydrophobicContact CD2-CG 4.39Å; L26-F73 HydrophobicContact CD2-CZ 4.24Å
27L97.4Very high95.4Very high11 Ų1158.7 Ų58.76%0.05827%0.274CS..Hα-helixtrans-58.1-45.7177.5177.362.1000111G23 Q24 R29 V30 C31 L44 F75G23-L27 PolarHBondContact O-N 3.44Å; Q24-L27 PolarHBondContact O-N 3.11Å; L27-R29 VanDerWaalsContact C-N 3.34Å; L27-R29 PolarHBondContact O-N 3.05Å; L27-V30 WeakPolarHBondContact O-CB 3.33Å; L27-V30 PolarHBondContact O-N 3.13Å; L27-V30 VanDerWaalsContact O-N 3.09Å; L27-C31 PolarHBondContact O-N 2.83Å; L27-C31 PolarHBondContact O-SG 2.76Å; L27-C31 VanDerWaalsContact O-SG 3.37Å; L27-L44 HydrophobicContact CB-CD1 4.18Å; L27-L44 HydrophobicContact CB-CG 4.44Å; L27-L44 HydrophobicContact CD1-CG 4.15Å; L27-F75 HydrophobicContact CD1-CD2 4.21Å; L27-F75 HydrophobicContact CD1-CE2 3.84Å
28K96.5Very high95.5Very high105 Ų10558.6 Ų58.646%0.45727%0.274SS..Hα-helixtrans-57.9-44.9178.2-165.7-170.8-176.2-126.70111.9Q24 L26 V30 C31 E32Q24-K28 VanDerWaalsContact O-CB 3.32Å; Q24-K28 WeakPolarHBondContact O-CB 3.47Å; Q24-K28 PolarHBondContact O-N 3.08Å; L26-K28 VanDerWaalsContact C-N 3.31Å; L26-K28 PolarHBondContact O-N 2.78Å; K28-V30 VanDerWaalsContact C-N 3.3Å; K28-V30 PolarHBondContact O-N 3.39Å; K28-C31 PolarHBondContact O-N 2.98Å; K28-E32 WeakPolarHBondContact CE-OE1 3.35Å; K28-E32 HydrophobicContact CG-CG 4.42Å; K28-E32 IonicContact NZ-OE1 3.23Å; K28-E32 PolarHBondContact NZ-OE1 3.13Å; K28-E32 WeakPolarHBondContact O-CB 3.4Å; K28-E32 VanDerWaalsContact O-CG 3.26Å; K28-E32 WeakPolarHBondContact O-CG 3.28Å; K28-E32 PolarHBondContact O-N 2.89Å
29R97.7Very high95.6Very high85 Ų8553.6 Ų53.632%0.32125%0.25SS..Hα-helixtrans-62.5-36.6176.3-73.1-176.9-175.6-166.82.2113V16 D25 L26 L27 H33V16-R29 PolarHBondContact O-NH1 3Å; D25-R29 WeakPolarHBondContact O-CG 3.49Å; D25-R29 PolarHBondContact O-N 2.99Å; L26-R29 PolarHBondContact O-N 3.37Å; L27-R29 VanDerWaalsContact C-N 3.34Å; L27-R29 PolarHBondContact O-N 3.05Å; R29-H33 WeakPolarHBondContact O-CB 3.49Å; R29-H33 PolarHBondContact O-N 3.29Å
30V97.8Very high95.9Very high0 Ų047.8 Ų47.80%023%0.226CC..Hα-helixtrans-66.1-48.3174.7175.20000110V5 L7 Y13 L26 L27 K28 E32 H33 L34 L44 F75V5-V30 HydrophobicContact CB-CG2 4.31Å; V5-V30 HydrophobicContact CG1-CG2 4.17Å; V5-V30 HydrophobicContact CG2-CG2 3.95Å; L7-V30 HydrophobicContact CD2-CG1 3.78Å; Y13-V30 HydrophobicContact CD1-CG2 3.85Å; Y13-V30 HydrophobicContact CE1-CG2 4.16Å; L26-V30 WeakPolarHBondContact O-CG2 3.47Å; L26-V30 PolarHBondContact O-N 2.75Å; L26-V30 VanDerWaalsContact O-N 3.09Å; L27-V30 WeakPolarHBondContact O-CB 3.33Å; L27-V30 PolarHBondContact O-N 3.13Å; L27-V30 VanDerWaalsContact O-N 3.09Å; K28-V30 VanDerWaalsContact C-N 3.3Å; K28-V30 PolarHBondContact O-N 3.39Å; V30-E32 VanDerWaalsContact C-N 3.35Å; V30-E32 PolarHBondContact O-N 3.46Å; V30-H33 WeakPolarHBondContact O-CB 3.38Å; V30-H33 PolarHBondContact O-N 3.24Å; V30-L34 HydrophobicContact CG1-CD1 4.03Å; V30-L34 HydrophobicContact CG1-CG 4.4Å; V30-L34 WeakPolarHBondContact O-CG 3.5Å; V30-L34 PolarHBondContact O-N 2.72Å; V30-L44 HydrophobicContact CG2-CD2 4.41Å; V30-F75 HydrophobicContact CG1-CB 4.43Å; V30-F75 HydrophobicContact CG1-CD2 3.59Å; V30-F75 HydrophobicContact CG1-CE2 3.93Å; V30-F75 HydrophobicContact CG1-CG 4.04Å
31C96.9Very high96Very high2 Ų242.7 Ų42.71%0.01420%0.202CC..Hα-helixtrans-62.8-39.5177.6-62.80000112.5L27 K28 L34 N35 L36 E39L27-C31 PolarHBondContact O-N 2.83Å; L27-C31 PolarHBondContact O-SG 2.76Å; L27-C31 VanDerWaalsContact O-SG 3.37Å; K28-C31 PolarHBondContact O-N 2.98Å; C31-L34 CarbonylContact O-C 3.58Å; C31-L34 PolarHBondContact O-N 3.18Å; C31-N35 WeakPolarHBondContact O-CA 3.25Å; C31-N35 PolarHBondContact O-N 3.1Å; C31-L36 HydrophobicContact CB-CB 4.37Å; C31-L36 PolarHBondContact O-N 2.73Å; C31-E39 HydrophobicContact CB-CB 4.17Å
32E95.7Very high96.1Very high113 Ų11342.7 Ų42.753%0.52820%0.2SC..Hα-helixtrans-61.3-43.7173.4-75.5169.4177.500111.3K28 V30 N35K28-E32 WeakPolarHBondContact CE-OE1 3.35Å; K28-E32 HydrophobicContact CG-CG 4.42Å; K28-E32 IonicContact NZ-OE1 3.23Å; K28-E32 PolarHBondContact NZ-OE1 3.13Å; K28-E32 WeakPolarHBondContact O-CB 3.4Å; K28-E32 VanDerWaalsContact O-CG 3.26Å; K28-E32 WeakPolarHBondContact O-CG 3.28Å; K28-E32 PolarHBondContact O-N 2.89Å; V30-E32 VanDerWaalsContact C-N 3.35Å; V30-E32 PolarHBondContact O-N 3.46Å; E32-N35 PolarHBondContact O-N 3.41Å
33H95.3Very high96.2Very high104 Ų10438 Ų3848%0.48118%0.181SC..Hα-helixtrans-63.2-40.7175.3173.462000112.6Y13 R29 V30 N35Y13-H33 HydrophobicContact CD2-CB 3.99Å; Y13-H33 AromaticContact CD2-CD2 3.27Å; Y13-H33 WeakPolarHBondContact CD2-CD2 3.46Å; Y13-H33 AromaticContact CD2-CE1 3.9Å; Y13-H33 AromaticContact CD2-CG 3.42Å; Y13-H33 VanDerWaalsContact CD2-CG 3.42Å; Y13-H33 AromaticContact CD2-ND1 3.82Å; Y13-H33 AromaticContact CD2-NE2 3.57Å; Y13-H33 HydrophobicContact CE2-CB 3.66Å; Y13-H33 AromaticContact CE2-CD2 3.84Å; Y13-H33 AromaticContact CE2-CG 3.46Å; Y13-H33 VanDerWaalsContact CE2-CG 3.46Å; Y13-H33 AromaticContact CE2-ND1 3.76Å; Y13-H33 AromaticContact CG-CD2 3.81Å; R29-H33 WeakPolarHBondContact O-CB 3.49Å; R29-H33 PolarHBondContact O-N 3.29Å; V30-H33 WeakPolarHBondContact O-CB 3.38Å; V30-H33 PolarHBondContact O-N 3.24Å; H33-N35 VanDerWaalsContact C-N 3.25Å; H33-N35 PolarHBondContact O-N 3.46Å
34L94.7Very high96.3Very high13 Ų1338.1 Ų38.17%0.06818%0.182CC..Hα-helixtrans-80.3-5.1178.5-64.8-176.8000113.6L7 V30 C31 L36 F75 I91 Y95L7-L34 HydrophobicContact CD1-CD2 3.6Å; L7-L34 HydrophobicContact CD1-CG 4.46Å; L7-L34 HydrophobicContact CD2-CD1 4.26Å; V30-L34 HydrophobicContact CG1-CD1 4.03Å; V30-L34 HydrophobicContact CG1-CG 4.4Å; V30-L34 WeakPolarHBondContact O-CG 3.5Å; V30-L34 PolarHBondContact O-N 2.72Å; C31-L34 CarbonylContact O-C 3.58Å; C31-L34 PolarHBondContact O-N 3.18Å; L34-L36 VanDerWaalsContact C-N 3.26Å; L34-L36 HydrophobicContact CB-CD1 3.81Å; L34-L36 HydrophobicContact CB-CG 3.9Å; L34-L36 HydrophobicContact CD1-CD1 3.7Å; L34-L36 HydrophobicContact CG-CD1 4.44Å; L34-L36 PolarHBondContact O-N 3.3Å; L34-F75 HydrophobicContact CD1-CD1 3.92Å; L34-F75 HydrophobicContact CD1-CE1 3.58Å; L34-F75 HydrophobicContact CD1-CZ 3.91Å; L34-I91 WeakPolarHBondContact O-CD1 3.19Å; L34-Y95 HydrophobicContact CD1-CE1 3.89Å; L34-Y95 HydrophobicContact CD2-CE1 4.37Å; L34-Y95 WeakPolarHBondContact CD2-OH 3.11Å
35N94.5Very high96.3Very high70 Ų7035 Ų3537%0.37417%0.168SC..THydrogen-bonded Turntrans56.636-174.5-162.329.2000113.9C31 E32 H33 R317 P320C31-N35 WeakPolarHBondContact O-CA 3.25Å; C31-N35 PolarHBondContact O-N 3.1Å; E32-N35 PolarHBondContact O-N 3.41Å; H33-N35 VanDerWaalsContact C-N 3.25Å; H33-N35 PolarHBondContact O-N 3.46Å; N35-R317 VanDerWaalsContact CG-NH1 3.27Å; N35-R317 PolarHBondContact ND2-NH1 3.35Å; N35-R317 PolarHBondContact O-NH2 3.02Å; N35-R317 PolarHBondContact OD1-NH1 3.44Å; N35-P320 VanDerWaalsContact ND2-CB 3.31Å; N35-P320 WeakPolarHBondContact ND2-CB 3.35Å
36L94.8Very high96.1Very high6 Ų633.2 Ų33.23%0.03116%0.158CC..  trans-95.1121.7179.9-74.8170.5000111.3C31 L34 F42 F75 I91 Y95C31-L36 HydrophobicContact CB-CB 4.37Å; C31-L36 PolarHBondContact O-N 2.73Å; L34-L36 VanDerWaalsContact C-N 3.26Å; L34-L36 HydrophobicContact CB-CD1 3.81Å; L34-L36 HydrophobicContact CB-CG 3.9Å; L34-L36 HydrophobicContact CD1-CD1 3.7Å; L34-L36 HydrophobicContact CG-CD1 4.44Å; L34-L36 PolarHBondContact O-N 3.3Å; L36-F42 HydrophobicContact CD1-CD2 4.39Å; L36-F42 HydrophobicContact CD1-CE2 4.12Å; L36-F42 HydrophobicContact CD1-CZ 4.32Å; L36-F42 HydrophobicContact CD2-CE2 4.37Å; L36-F75 HydrophobicContact CD1-CE1 3.96Å; L36-F75 HydrophobicContact CD1-CZ 3.73Å; L36-I91 HydrophobicContact CD2-CB 4.34Å; L36-I91 HydrophobicContact CD2-CD1 4.42Å; L36-I91 HydrophobicContact CD2-CG1 3.88Å; L36-I91 HydrophobicContact CD2-CG2 3.88Å; L36-Y95 HydrophobicContact CD1-CD2 4.21Å; L36-Y95 HydrophobicContact CD1-CE2 4.48Å; L36-Y95 HydrophobicContact CD1-CG 4.38Å; L36-Y95 HydrophobicContact CD2-CD2 4.01Å; L36-Y95 HydrophobicContact CG-CD2 4.46Å
37L94.8Very high95.7Very high75 Ų7538.3 Ų38.339%0.39318%0.177SC..SBendtrans-95.4-28.7175.8-60.3-179.6000113.7E39 E89 I315 R317L37-E39 PolarHBondContact O-N 2.88Å; L37-E89 WeakPolarHBondContact CB-OE2 3.37Å; L37-E89 PolarHBondContact N-OE2 2.89Å; L37-I315 HydrophobicContact CB-CD1 3.89Å; L37-I315 HydrophobicContact CB-CG1 4.48Å; L37-I315 HydrophobicContact CD1-CD1 4.05Å; L37-I315 HydrophobicContact CD1-CG1 3.97Å; L37-I315 HydrophobicContact CD1-CG2 3.78Å; L37-R317 VanDerWaalsContact CD1-NE 3.31Å
38E95.4Very high94.9Very high1 Ų143 Ų431%0.00520%0.202CC..  trans-8150176.1-60.1179.4100.400111.4D40 Y41 T88 E89 T92 I315E38-D40 VanDerWaalsContact C-N 3.26Å; E38-D40 PolarHBondContact O-N 2.94Å; E38-Y41 HydrophobicContact CB-CD2 4.09Å; E38-Y41 HydrophobicContact CB-CE2 4.29Å; E38-T88 PolarHBondContact OE1-N 3.18Å; E38-T88 PolarHBondContact OE2-N 2.92Å; E38-E89 PolarHBondContact OE2-N 3.46Å; E38-T92 HydrophobicContact CB-CG2 3.89Å; E38-T92 WeakPolarHBondContact OE2-CB 3.5Å; E38-T92 PolarHBondContact OE2-OG1 2.82Å; E38-I315 HydrophobicContact CG-CD1 4.37Å
39E95.4Very high94.1Very high39 Ų3940.8 Ų40.818%0.18220%0.2CC..G310 helixtrans-63.2-24.6-169.461.7173.2-156.100114.8C31 L37 Y41 F42C31-E39 HydrophobicContact CB-CB 4.17Å; L37-E39 PolarHBondContact O-N 2.88Å; E39-Y41 PolarHBondContact O-N 2.83Å; E39-Y41 VanDerWaalsContact O-N 3.13Å; E39-F42 PolarHBondContact O-N 2.99Å
40D96.1Very high93.1Very high16 Ų1641.3 Ų41.39%0.08622%0.222CC..G310 helixtrans-66.5-18.9-172-60.1-85.2000113.4E38 F42 F79 F277 R303 T308E38-D40 VanDerWaalsContact C-N 3.26Å; E38-D40 PolarHBondContact O-N 2.94Å; D40-F42 PolarHBondContact O-N 2.81Å; D40-F79 VanDerWaalsContact O-CD2 3.23Å; D40-F79 WeakPolarHBondContact O-CD2 3.47Å; D40-F277 HydrophobicContact CB-CE2 3.92Å; D40-R303 WeakPolarHBondContact OD1-CB 3.21Å; D40-R303 PolarHBondContact OD1-N 2.8Å; D40-R303 IonicContact OD1-NE 2.73Å; D40-R303 IonicContact OD2-CZ 2.93Å; D40-R303 IonicContact OD2-NE 3.6Å; D40-R303 PolarHBondContact OD2-NE 2.87Å; D40-R303 IonicContact OD2-NH2 2.6Å; D40-R303 PolarHBondContact OD2-NH2 2.86Å; D40-T308 HydrophobicContact CB-CG2 4.12Å; D40-T308 WeakPolarHBondContact CB-OG1 3.34Å; D40-T308 PolarHBondContact OD2-OG1 3.14Å
41Y97.5Very high92Very high5 Ų547.8 Ų47.82%0.0226%0.262CS..G310 helixtrans-75.4-14.5175.9-66-72.9000112.9E38 E39 K78 F79 P81 L87 T92 F277 T308E38-Y41 HydrophobicContact CB-CD2 4.09Å; E38-Y41 HydrophobicContact CB-CE2 4.29Å; E39-Y41 PolarHBondContact O-N 2.83Å; E39-Y41 VanDerWaalsContact O-N 3.13Å; Y41-K78 PolarHBondContact O-N 3.25Å; Y41-F79 HydrophobicContact CD1-CB 4.31Å; Y41-F79 WeakPolarHBondContact CD1-O 3.4Å; Y41-F79 PolarHBondContact O-N 3.48Å; Y41-P81 HydrophobicContact CE1-CB 4.03Å; Y41-P81 HydrophobicContact CE1-CG 4.43Å; Y41-L87 HydrophobicContact CD2-CD2 3.83Å; Y41-L87 HydrophobicContact CE1-CD2 4.39Å; Y41-L87 HydrophobicContact CE2-CD2 3.33Å; Y41-T92 HydrophobicContact CD2-CG2 4.44Å; Y41-F277 HydrophobicContact CD1-CE1 4.03Å; Y41-F277 AromaticContact CD1-CZ 3.82Å; Y41-F277 HydrophobicContact CD1-CZ 3.82Å; Y41-F277 AromaticContact CE1-CE1 3.85Å; Y41-F277 HydrophobicContact CE1-CE1 3.85Å; Y41-F277 AromaticContact CE1-CZ 3.71Å; Y41-F277 HydrophobicContact CE1-CZ 3.71Å; Y41-T308 HydrophobicContact CD2-CG2 4.43Å; Y41-T308 HydrophobicContact CE2-CG2 3.83Å
42F97.9Very high91.3Very high7 Ų749.4 Ų49.43%0.03127%0.273CS..EExtended strand (participates in β ladder)trans-109.7165.9-172.3-57.8-84.3000112.7L8 L36 E39 D40 F75 N76 V77 T92L8-F42 HydrophobicContact CD1-CE1 4.47Å; L36-F42 HydrophobicContact CD1-CD2 4.39Å; L36-F42 HydrophobicContact CD1-CE2 4.12Å; L36-F42 HydrophobicContact CD1-CZ 4.32Å; L36-F42 HydrophobicContact CD2-CE2 4.37Å; E39-F42 PolarHBondContact O-N 2.99Å; D40-F42 PolarHBondContact O-N 2.81Å; F42-F75 HydrophobicContact CB-CD2 4.47Å; F42-F75 HydrophobicContact CB-CE1 4.22Å; F42-F75 HydrophobicContact CB-CE2 3.53Å; F42-F75 HydrophobicContact CB-CZ 3.38Å; F42-F75 HydrophobicContact CD1-CD1 4.43Å; F42-F75 AromaticContact CD1-CE1 3.49Å; F42-F75 HydrophobicContact CD1-CE1 3.49Å; F42-F75 VanDerWaalsContact CD1-CE1 3.49Å; F42-F75 HydrophobicContact CD1-CE2 4.38Å; F42-F75 AromaticContact CD1-CZ 3.47Å; F42-F75 HydrophobicContact CD1-CZ 3.47Å; F42-F75 VanDerWaalsContact CD1-CZ 3.47Å; F42-F75 HydrophobicContact CD2-CZ 4.05Å; F42-F75 HydrophobicContact CE1-CE1 4.02Å; F42-F75 HydrophobicContact CE1-CZ 4.26Å; F42-F75 AromaticContact CG-CE1 3.91Å; F42-F75 HydrophobicContact CG-CE1 3.91Å; F42-F75 HydrophobicContact CG-CE2 4.06Å; F42-F75 AromaticContact CG-CZ 3.35Å; F42-F75 HydrophobicContact CG-CZ 3.35Å; F42-N76 CarbonylContact C-O 3.33Å; F42-N76 WeakPolarHBondContact CA-O 3.46Å; F42-V77 HydrophobicContact CD1-CG2 4.06Å; F42-V77 HydrophobicContact CE1-CG2 3.75Å; F42-T92 HydrophobicContact CE2-CG2 4.01Å; F42-T92 HydrophobicContact CZ-CG2 4.15Å
43G97.3Very high91Very high5 Ų545.3 Ų45.35%0.05225%0.254CS..EExtended strand (participates in β ladder)trans-161.6167.117400000112.5N76G43-N76 PolarHBondContact N-O 3.43Å; G43-N76 PolarHBondContact O-N 3.3Å
44L97.5Very high90.9Very high5 Ų543 Ų433%0.02625%0.247CC..EExtended strand (participates in β ladder)trans-98.6135.6173.4-62.2175000110V5 L26 L27 V30 L56 F73 T74 F75V5-L44 HydrophobicContact CG1-CD2 3.72Å; L26-L44 HydrophobicContact CB-CD1 4.08Å; L26-L44 HydrophobicContact CD2-CD1 3.7Å; L26-L44 HydrophobicContact CG-CD1 3.6Å; L27-L44 HydrophobicContact CB-CD1 4.18Å; L27-L44 HydrophobicContact CB-CG 4.44Å; L27-L44 HydrophobicContact CD1-CG 4.15Å; V30-L44 HydrophobicContact CG2-CD2 4.41Å; L44-L56 HydrophobicContact CB-CB 4.09Å; L44-L56 HydrophobicContact CB-CD2 4.06Å; L44-L56 HydrophobicContact CD1-CD2 4.01Å; L44-L56 WeakPolarHBondContact O-CB 3.34Å; L44-L56 PolarHBondContact O-N 2.91Å; L44-F73 HydrophobicContact CB-CB 4.47Å; L44-F73 HydrophobicContact CD2-CB 4.48Å; L44-T74 CarbonylContact C-O 3.59Å; L44-T74 WeakPolarHBondContact CA-O 3.44Å; L44-F75 HydrophobicContact CD2-CB 4.26Å; L44-F75 HydrophobicContact CD2-CD2 4.06Å
45A95.5Very high90.8Very high0 Ų044 Ų440%025%0.25CC..EExtended strand (participates in β ladder)trans-126.3153.6179.200000112.3K53 T54 W55 F73 T74A45-K53 HydrophobicContact CB-CB 4.12Å; A45-K53 HydrophobicContact CB-CD 3.95Å; A45-K53 HydrophobicContact CB-CG 4.32Å; A45-T54 WeakPolarHBondContact CA-O 3.28Å; A45-W55 HydrophobicContact CB-CE3 3.97Å; A45-W55 HydrophobicContact CB-CZ3 4.15Å; A45-F73 WeakPolarHBondContact O-CA 3.44Å; A45-T74 PolarHBondContact N-O 2.82Å; A45-T74 PolarHBondContact O-N 2.92Å
46L93Very high90.8Very high35 Ų3541 Ų4118%0.18323%0.234CC..EExtended strand (participates in β ladder)trans-110.6139.8169.8-66.7141.8000107.9K53 T54 V66 N72 F73L46-K53 CarbonylContact O-C 3.43Å; L46-K53 WeakPolarHBondContact O-CA 3.37Å; L46-T54 PolarHBondContact N-O 2.73Å; L46-T54 PolarHBondContact O-N 2.78Å; L46-V66 HydrophobicContact CD1-CG2 3.66Å; L46-V66 HydrophobicContact CD2-CG1 4.07Å; L46-V66 HydrophobicContact CD2-CG2 3.82Å; L46-V66 HydrophobicContact CG-CG2 4.34Å; L46-N72 WeakPolarHBondContact CD2-O 3.39Å; L46-F73 HydrophobicContact CD1-CE1 4.18Å; L46-F73 HydrophobicContact CD2-CD1 3.91Å; L46-F73 HydrophobicContact CD2-CE1 3.78Å; L46-F73 HydrophobicContact CG-CD1 3.93Å; L46-F73 HydrophobicContact CG-CE1 3.97Å
47W87.4Confident90.7Very high107 Ų10741.5 Ų41.541%0.40524%0.236SC..EExtended strand (participates in β ladder)trans-97.8117.8177.9-66.678.7000109.9A50 K53 T74W47-A50 WeakPolarHBondContact CZ3-O 3.24Å; W47-K53 HydrophobicContact CD2-CB 4.06Å; W47-K53 HydrophobicContact CE3-CB 4.18Å; W47-K53 HydrophobicContact CZ2-CD 4.31Å; W47-K53 HydrophobicContact CZ3-CB 4.49Å; W47-T74 PolarHBondContact NE1-OG1 2.88Å
48D81Confident90.6Very high111 Ų11139.3 Ų39.359%0.59423%0.228SC*.SBendtrans-82.8-29172.9-59.4-52.1000110.8S52 T54D48-S52 PolarHBondContact N-O 3.1Å; D48-T54 PolarHBondContact OD2-OG1 3.27Å
49S80.8Confident90.4Very high57 Ų5741.7 Ų41.740%0.39925%0.248SC..SBendtrans-155.1177175.171.80000109.5T51 S52S49-T51 PolarHBondContact O-N 2.87Å; S49-T51 PolarHBondContact OG-N 2.85Å; S49-S52 PolarHBondContact N-O 3.15Å; S49-S52 PolarHBondContact O-N 3.01Å; S49-S52 WeakPolarHBondContact OG-CB 3.21Å; S49-S52 PolarHBondContact OG-N 3.47Å; S49-S52 VanDerWaalsContact OG-N 3.1Å
50A76.8Confident90.3Very high97 Ų9744.4 Ų44.480%0.80226%0.259SS*.SBendtrans-57.6-19.4177.900000114.8W47W47-A50 WeakPolarHBondContact CZ3-O 3.24Å
51T74.3Confident90.3Very high135 Ų13545.5 Ų45.583%0.82826%0.263SS*.SBendtrans-125.8-8.8-176.455.80000113.7S49S49-T51 PolarHBondContact O-N 2.87Å; S49-T51 PolarHBondContact OG-N 2.85Å
52S82.3Confident90.2Very high36 Ų3645.3 Ų45.325%0.25226%0.263SS..  trans-113109.8178.4-178.70000110.4D48 S49 K266D48-S52 PolarHBondContact N-O 3.1Å; S49-S52 PolarHBondContact N-O 3.15Å; S49-S52 PolarHBondContact O-N 3.01Å; S49-S52 WeakPolarHBondContact OG-CB 3.21Å; S49-S52 PolarHBondContact OG-N 3.47Å; S49-S52 VanDerWaalsContact OG-N 3.1Å; S52-K266 PolarHBondContact OG-NZ 3.46Å
53K89.6Confident90Very high28 Ų2848.3 Ų48.312%0.12228%0.276CS..EExtended strand (participates in β ladder)trans-103.2148.7167.672.5-178.8178.5178.70112.2A45 L46 W47 W55 K266A45-K53 HydrophobicContact CB-CB 4.12Å; A45-K53 HydrophobicContact CB-CD 3.95Å; A45-K53 HydrophobicContact CB-CG 4.32Å; L46-K53 CarbonylContact O-C 3.43Å; L46-K53 WeakPolarHBondContact O-CA 3.37Å; W47-K53 HydrophobicContact CD2-CB 4.06Å; W47-K53 HydrophobicContact CE3-CB 4.18Å; W47-K53 HydrophobicContact CZ2-CD 4.31Å; W47-K53 HydrophobicContact CZ3-CB 4.49Å; K53-W55 HydrophobicContact CD-CZ2 4.44Å; K53-W55 VanDerWaalsContact CE-CZ2 3.46Å; K53-K266 WeakPolarHBondContact O-CE 3.29Å; K53-K266 PolarHBondContact O-NZ 3.27Å
54T91.3Very high89.8Confident55 Ų5555.2 Ų55.234%0.33730%0.304SS..EExtended strand (participates in β ladder)trans-118.4124.8172.4-68.90000108.6A45 L46 D48A45-T54 WeakPolarHBondContact CA-O 3.28Å; L46-T54 PolarHBondContact N-O 2.73Å; L46-T54 PolarHBondContact O-N 2.78Å; D48-T54 PolarHBondContact OD2-OG1 3.27Å
55W94.1Very high89.5Confident34 Ų3457.8 Ų57.813%0.12932%0.316CS..EExtended strand (participates in β ladder)trans-68.6136.1177.7-64.2109.1000111.6A45 K53 D57 N76 V77 K78A45-W55 HydrophobicContact CB-CE3 3.97Å; A45-W55 HydrophobicContact CB-CZ3 4.15Å; K53-W55 HydrophobicContact CD-CZ2 4.44Å; K53-W55 VanDerWaalsContact CE-CZ2 3.46Å; W55-D57 PolarHBondContact O-N 2.7Å; W55-N76 HydrophobicContact CH2-CB 3.75Å; W55-N76 HydrophobicContact CZ3-CB 3.99Å; W55-V77 WeakPolarHBondContact CH2-O 3.32Å; W55-K78 HydrophobicContact CD2-CD 4.05Å; W55-K78 HydrophobicContact CD2-CG 4.13Å; W55-K78 HydrophobicContact CE3-CB 4.42Å; W55-K78 HydrophobicContact CE3-CD 4.1Å; W55-K78 HydrophobicContact CE3-CG 4.28Å; W55-K78 HydrophobicContact CG-CD 4.48Å; W55-K78 VanDerWaalsContact CH2-CA 3.49Å; W55-K78 HydrophobicContact CH2-CB 3.59Å; W55-K78 HydrophobicContact CH2-CG 3.95Å; W55-K78 HydrophobicContact CZ2-CB 3.9Å; W55-K78 HydrophobicContact CZ2-CG 3.79Å; W55-K78 HydrophobicContact CZ3-CB 3.88Å; W55-K78 HydrophobicContact CZ3-CD 4.39Å; W55-K78 HydrophobicContact CZ3-CG 4.19Å
56L94.6Very high89.3Confident8 Ų858.6 Ų58.64%0.04232%0.321CS..  trans-66.5128168.9-173.466.4000109L44 S58 I62 Q65 F73L44-L56 HydrophobicContact CB-CB 4.09Å; L44-L56 HydrophobicContact CB-CD2 4.06Å; L44-L56 HydrophobicContact CD1-CD2 4.01Å; L44-L56 WeakPolarHBondContact O-CB 3.34Å; L44-L56 PolarHBondContact O-N 2.91Å; L56-S58 PolarHBondContact O-N 2.83Å; L56-I62 HydrophobicContact CD2-CG1 4.4Å; L56-Q65 HydrophobicContact CD1-CB 4.13Å; L56-Q65 HydrophobicContact CD1-CG 4.48Å; L56-F73 HydrophobicContact CD1-CE1 4Å; L56-F73 HydrophobicContact CD2-CD1 4.35Å; L56-F73 HydrophobicContact CD2-CE1 3.98Å; L56-F73 HydrophobicContact CD2-CZ 4.41Å; L56-F73 HydrophobicContact CG-CE1 4.48Å
57D92.9Very high88.9Confident15 Ų1568.7 Ų68.78%0.0836%0.357CS..  trans-77.4110.1177.3-170.4-39.3000108.8W55 A59 K60 Q65W55-D57 PolarHBondContact O-N 2.7Å; D57-A59 PolarHBondContact O-N 2.74Å; D57-A59 PolarHBondContact OD1-N 3.01Å; D57-K60 HydrophobicContact CB-CB 4.24Å; D57-K60 HydrophobicContact CB-CD 4.14Å; D57-K60 HydrophobicContact CB-CG 4.35Å; D57-K60 PolarHBondContact O-N 2.84Å; D57-K60 VanDerWaalsContact O-N 3.15Å; D57-K60 WeakPolarHBondContact OD2-CD 3.35Å; D57-K60 WeakPolarHBondContact OD2-CE 3.16Å; D57-K60 IonicContact OD2-NZ 3.78Å; D57-K60 PolarHBondContact OD2-NZ 3.32Å; D57-Q65 PolarHBondContact O-NE2 2.99Å
58S92.3Very high88.6Confident30 Ų3066.3 Ų66.321%0.2137%0.365CS..THydrogen-bonded Turntrans-59.2-31-174-54.50000113.4G23 Q24 L56 K60G23-S58 PolarHBondContact N-O 3.36Å; Q24-S58 PolarHBondContact N-O 2.72Å; Q24-S58 VanDerWaalsContact OE1-CB 3.29Å; L56-S58 PolarHBondContact O-N 2.83Å; S58-K60 VanDerWaalsContact C-N 3.34Å; S58-K60 PolarHBondContact O-N 3.12Å
59A91.2Very high88.5Confident51 Ų5165.8 Ų65.842%0.42137%0.366SS..THydrogen-bonded Turntrans-81.8-10.9-176.900000113.7D57D57-A59 PolarHBondContact O-N 2.74Å; D57-A59 PolarHBondContact OD1-N 3.01Å
60K93.4Very high88.7Confident95 Ų9566.3 Ų66.341%0.41337%0.368SS..SBendtrans-107.2149-174.3-71.9-178.3-176.1136.40112.6K22 G23 D57 S58 I62 Q65K22-K60 CarbonylContact C-O 3.52Å; K22-K60 VanDerWaalsContact CA-O 3.3Å; K22-K60 WeakPolarHBondContact CA-O 3.17Å; G23-K60 PolarHBondContact N-O 2.96Å; D57-K60 HydrophobicContact CB-CB 4.24Å; D57-K60 HydrophobicContact CB-CD 4.14Å; D57-K60 HydrophobicContact CB-CG 4.35Å; D57-K60 PolarHBondContact O-N 2.84Å; D57-K60 VanDerWaalsContact O-N 3.15Å; D57-K60 WeakPolarHBondContact OD2-CD 3.35Å; D57-K60 WeakPolarHBondContact OD2-CE 3.16Å; D57-K60 IonicContact OD2-NZ 3.78Å; D57-K60 PolarHBondContact OD2-NZ 3.32Å; S58-K60 VanDerWaalsContact C-N 3.34Å; S58-K60 PolarHBondContact O-N 3.12Å; K60-I62 PolarHBondContact O-N 2.74Å; K60-Q65 HydrophobicContact CB-CG 4.24Å; K60-Q65 PolarHBondContact O-NE2 3.48Å
61E95.3Very high89.4Confident40 Ų4062 Ų6219%0.18733%0.331CS..BIsolated β-bridgetrans-57.1133.3172.5-66.7170.9-139.300111.2H20 A21 K63 K64H20-E61 IonicContact ND1-OE2 2.96Å; A21-E61 WeakPolarHBondContact O-CA 3.5Å; E61-K63 HydrophobicContact CB-CG 4.33Å; E61-K63 PolarHBondContact O-N 2.85Å; E61-K63 WeakPolarHBondContact OE2-CE 3.44Å; E61-K63 IonicContact OE2-NZ 3.52Å; E61-K64 HydrophobicContact CB-CB 4.48Å; E61-K64 HydrophobicContact CB-CD 4.09Å; E61-K64 HydrophobicContact CB-CG 4.14Å; E61-K64 VanDerWaalsContact CD-NZ 3.28Å; E61-K64 PolarHBondContact O-N 2.93Å; E61-K64 VanDerWaalsContact O-N 3.13Å; E61-K64 IonicContact OE1-NZ 3.74Å; E61-K64 PolarHBondContact OE1-NZ 2.93Å; E61-K64 WeakPolarHBondContact OE2-CE 3.31Å; E61-K64 IonicContact OE2-NZ 3.85Å; E61-K64 PolarHBondContact OE2-NZ 3.46Å
62I95.1Very high90.3Very high1 Ų159.8 Ų59.81%0.00531%0.314CS..G310 helixtrans-61.5-43.6-175.7-61.1169.8000111.2V17 A21 L26 L56 K60 K64 Q65 V66 W71 F73V17-I62 HydrophobicContact CG2-CD1 4.31Å; A21-I62 HydrophobicContact CB-CD1 4.39Å; A21-I62 PolarHBondContact O-N 2.9Å; L26-I62 HydrophobicContact CB-CD1 3.75Å; L26-I62 HydrophobicContact CD2-CD1 4.01Å; L56-I62 HydrophobicContact CD2-CG1 4.4Å; K60-I62 PolarHBondContact O-N 2.74Å; I62-K64 PolarHBondContact O-N 3.02Å; I62-Q65 WeakPolarHBondContact O-CB 3.47Å; I62-Q65 PolarHBondContact O-N 3.34Å; I62-V66 HydrophobicContact CG2-CG2 4.26Å; I62-V66 PolarHBondContact O-N 3.15Å; I62-W71 HydrophobicContact CB-CE3 4.1Å; I62-W71 HydrophobicContact CB-CH2 4.28Å; I62-W71 HydrophobicContact CB-CZ3 3.79Å; I62-W71 HydrophobicContact CG2-CD2 3.79Å; I62-W71 HydrophobicContact CG2-CE3 3.34Å; I62-W71 HydrophobicContact CG2-CG 4.49Å; I62-W71 HydrophobicContact CG2-CH2 4.17Å; I62-W71 HydrophobicContact CG2-CZ3 3.55Å; I62-F73 HydrophobicContact CG2-CE2 4.4Å; I62-F73 HydrophobicContact CG2-CZ 3.66Å
63K93.7Very high91Very high69 Ų6958.3 Ų58.330%0.330%0.303SS..G310 helixtrans-59.7-20.3178.566.3172.3173.7-171.50114.9K19 H20 E61 Q65 W71K19-K63 HydrophobicContact CG-CD 4.44Å; K19-K63 VanDerWaalsContact O-CD 3.29Å; K19-K63 WeakPolarHBondContact O-CD 3.38Å; K19-K63 WeakPolarHBondContact O-CE 3.48Å; H20-K63 PolarHBondContact CE1-NZ 2.77Å; H20-K63 PolarHBondContact ND1-NZ 2.82Å; H20-K63 VanDerWaalsContact ND1-NZ 3.12Å; H20-K63 PolarHBondContact NE2-NZ 3.24Å; E61-K63 HydrophobicContact CB-CG 4.33Å; E61-K63 PolarHBondContact O-N 2.85Å; E61-K63 WeakPolarHBondContact OE2-CE 3.44Å; E61-K63 IonicContact OE2-NZ 3.52Å; K63-Q65 VanDerWaalsContact C-N 3.33Å; K63-W71 HydrophobicContact CB-CH2 3.72Å; K63-W71 HydrophobicContact CB-CZ2 3.64Å
64K93.4Very high91.3Very high150 Ų15058.3 Ų58.365%0.65231%0.305SS*.G310 helixtrans-85.9-11.8177.5-67.7179.7177.7160.30111.9E61 I62E61-K64 HydrophobicContact CB-CB 4.48Å; E61-K64 HydrophobicContact CB-CD 4.09Å; E61-K64 HydrophobicContact CB-CG 4.14Å; E61-K64 VanDerWaalsContact CD-NZ 3.28Å; E61-K64 PolarHBondContact O-N 2.93Å; E61-K64 VanDerWaalsContact O-N 3.13Å; E61-K64 IonicContact OE1-NZ 3.74Å; E61-K64 PolarHBondContact OE1-NZ 2.93Å; E61-K64 WeakPolarHBondContact OE2-CE 3.31Å; E61-K64 IonicContact OE2-NZ 3.85Å; E61-K64 PolarHBondContact OE2-NZ 3.46Å; I62-K64 PolarHBondContact O-N 3.02Å
65Q91.8Very high91.7Very high59 Ų5955.7 Ų55.728%0.27629%0.289SS..THydrogen-bonded Turntrans-109.5-33.7-175.4-56.6-173.271.500111.8L56 D57 K60 I62 K63L56-Q65 HydrophobicContact CD1-CB 4.13Å; L56-Q65 HydrophobicContact CD1-CG 4.48Å; D57-Q65 PolarHBondContact O-NE2 2.99Å; K60-Q65 HydrophobicContact CB-CG 4.24Å; K60-Q65 PolarHBondContact O-NE2 3.48Å; I62-Q65 WeakPolarHBondContact O-CB 3.47Å; I62-Q65 PolarHBondContact O-N 3.34Å; K63-Q65 VanDerWaalsContact C-N 3.33Å
66V90.2Very high91.8Very high18 Ų1854.4 Ų54.411%0.10929%0.285CS..  trans-118.1139.2-175.5-170.10000110.5L46 I62 W71 F73L46-V66 HydrophobicContact CD1-CG2 3.66Å; L46-V66 HydrophobicContact CD2-CG1 4.07Å; L46-V66 HydrophobicContact CD2-CG2 3.82Å; L46-V66 HydrophobicContact CG-CG2 4.34Å; I62-V66 HydrophobicContact CG2-CG2 4.26Å; I62-V66 PolarHBondContact O-N 3.15Å; V66-W71 HydrophobicContact CB-CG 4.36Å; V66-W71 HydrophobicContact CG1-CB 4.43Å; V66-W71 VanDerWaalsContact CG1-CD1 3.49Å; V66-W71 HydrophobicContact CG1-CG 4.07Å; V66-F73 HydrophobicContact CG2-CE1 3.73Å; V66-F73 HydrophobicContact CG2-CZ 3.85Å
67R85.1Confident92Very high247 Ų24754 Ų5493%0.93228%0.283SS*.  trans-106.1151.3175-62.6-177179.6-172.1-1.5110
68G82.1Confident92.2Very high56 Ų5654.1 Ų54.158%0.57728%0.283SS*.SBendtrans80.1175.5179.100000113.6W71G68-W71 PolarHBondContact O-NE1 3.2Å
69V78.6Confident92.4Very high100 Ų10052.8 Ų52.861%0.60627%0.273SS*.SBendtrans-143.5149.3171.5-720000109.1M1M1-V69 HydrophobicContact CE-CG1 3.6Å
70P83.8Confident92.8Very high68 Ų6851.3 Ų51.344%0.44226%0.257SS..SBendcis-67152.9-5.430.1-35.3000112.3H2 N72H2-P70 HydrophobicContact CB-CB 4.48Å; P70-N72 PolarHBondContact O-N 2.67Å
71W92.2Very high92.9Very high7 Ų746.9 Ų46.93%0.02724%0.238CC..EExtended strand (participates in β ladder)trans-80.3115.6174.1-65.7-28.3000109.8M1 H2 C3 K4 V17 I62 K63 V66 G68 F73M1-W71 HydrophobicContact CB-CE3 4.05Å; M1-W71 HydrophobicContact CB-CH2 3.73Å; M1-W71 HydrophobicContact CB-CZ2 4.42Å; M1-W71 HydrophobicContact CB-CZ3 3.52Å; M1-W71 HydrophobicContact CE-CH2 3.78Å; M1-W71 HydrophobicContact CE-CZ2 3.42Å; M1-W71 VanDerWaalsContact CE-CZ2 3.42Å; M1-W71 HydrophobicContact CG-CH2 3.65Å; M1-W71 HydrophobicContact CG-CZ2 4.3Å; M1-W71 HydrophobicContact CG-CZ3 3.96Å; H2-W71 PolarHBondContact O-N 3.31Å; H2-W71 VanDerWaalsContact O-N 3.07Å; C3-W71 CarbonylContact C-O 3.58Å; C3-W71 WeakPolarHBondContact CA-O 3.47Å; K4-W71 PolarHBondContact N-O 3.1Å; V17-W71 HydrophobicContact CG2-CE3 4.42Å; V17-W71 HydrophobicContact CG2-CZ3 4.01Å; I62-W71 HydrophobicContact CB-CE3 4.1Å; I62-W71 HydrophobicContact CB-CH2 4.28Å; I62-W71 HydrophobicContact CB-CZ3 3.79Å; I62-W71 HydrophobicContact CG2-CD2 3.79Å; I62-W71 HydrophobicContact CG2-CE3 3.34Å; I62-W71 HydrophobicContact CG2-CG 4.49Å; I62-W71 HydrophobicContact CG2-CH2 4.17Å; I62-W71 HydrophobicContact CG2-CZ3 3.55Å; K63-W71 HydrophobicContact CB-CH2 3.72Å; K63-W71 HydrophobicContact CB-CZ2 3.64Å; V66-W71 HydrophobicContact CB-CG 4.36Å; V66-W71 HydrophobicContact CG1-CB 4.43Å; V66-W71 VanDerWaalsContact CG1-CD1 3.49Å; V66-W71 HydrophobicContact CG1-CG 4.07Å; G68-W71 PolarHBondContact O-NE1 3.2Å; W71-F73 HydrophobicContact CB-CD2 4.43Å; W71-F73 HydrophobicContact CB-CE2 3.48Å; W71-F73 VanDerWaalsContact CB-CE2 3.48Å; W71-F73 HydrophobicContact CB-CZ 3.81Å; W71-F73 HydrophobicContact CG-CE2 4.49Å; W71-F73 HydrophobicContact CG-CZ 4.48Å
72N93.7Very high92.9Very high88 Ų8847.9 Ų47.947%0.47125%0.248SC..EExtended strand (participates in β ladder)trans-101131-178.9-59-43.1000110.4K4 L46 P70K4-N72 WeakPolarHBondContact CB-OD1 3.36Å; K4-N72 CarbonylContact O-C 3.51Å; K4-N72 WeakPolarHBondContact O-CA 3.41Å; L46-N72 WeakPolarHBondContact CD2-O 3.39Å; P70-N72 PolarHBondContact O-N 2.67Å
73F96.6Very high92.8Very high6 Ų650 Ų503%0.02626%0.259CS..EExtended strand (participates in β ladder)trans-133.3161.6177.8-56-80.9000110.5K4 V5 S6 L26 L44 A45 L46 L56 I62 V66 W71K4-F73 PolarHBondContact O-N 2.82Å; V5-F73 CarbonylContact C-O 3.57Å; V5-F73 WeakPolarHBondContact CA-O 3.5Å; V5-F73 HydrophobicContact CG1-CB 4.44Å; V5-F73 HydrophobicContact CG2-CB 4.33Å; V5-F73 HydrophobicContact CG2-CD2 4.44Å; S6-F73 PolarHBondContact N-O 3.32Å; L26-F73 HydrophobicContact CD2-CD2 3.62Å; L26-F73 HydrophobicContact CD2-CE2 3.52Å; L26-F73 HydrophobicContact CD2-CG 4.39Å; L26-F73 HydrophobicContact CD2-CZ 4.24Å; L44-F73 HydrophobicContact CB-CB 4.47Å; L44-F73 HydrophobicContact CD2-CB 4.48Å; A45-F73 WeakPolarHBondContact O-CA 3.44Å; L46-F73 HydrophobicContact CD1-CE1 4.18Å; L46-F73 HydrophobicContact CD2-CD1 3.91Å; L46-F73 HydrophobicContact CD2-CE1 3.78Å; L46-F73 HydrophobicContact CG-CD1 3.93Å; L46-F73 HydrophobicContact CG-CE1 3.97Å; L56-F73 HydrophobicContact CD1-CE1 4Å; L56-F73 HydrophobicContact CD2-CD1 4.35Å; L56-F73 HydrophobicContact CD2-CE1 3.98Å; L56-F73 HydrophobicContact CD2-CZ 4.41Å; L56-F73 HydrophobicContact CG-CE1 4.48Å; I62-F73 HydrophobicContact CG2-CE2 4.4Å; I62-F73 HydrophobicContact CG2-CZ 3.66Å; V66-F73 HydrophobicContact CG2-CE1 3.73Å; V66-F73 HydrophobicContact CG2-CZ 3.85Å; W71-F73 HydrophobicContact CB-CD2 4.43Å; W71-F73 HydrophobicContact CB-CE2 3.48Å; W71-F73 VanDerWaalsContact CB-CE2 3.48Å; W71-F73 HydrophobicContact CB-CZ 3.81Å; W71-F73 HydrophobicContact CG-CE2 4.49Å; W71-F73 HydrophobicContact CG-CZ 4.48Å
74T97Very high92.8Very high27 Ų2746.8 Ų46.817%0.16625%0.245CC..EExtended strand (participates in β ladder)trans-115.5139163.759.70000109.9S6 L44 A45 W47 N76S6-T74 CarbonylContact O-C 3.58Å; S6-T74 WeakPolarHBondContact O-CA 3.3Å; L44-T74 CarbonylContact C-O 3.59Å; L44-T74 WeakPolarHBondContact CA-O 3.44Å; A45-T74 PolarHBondContact N-O 2.82Å; A45-T74 PolarHBondContact O-N 2.92Å; W47-T74 PolarHBondContact NE1-OG1 2.88Å; T74-N76 WeakPolarHBondContact CB-OD1 3.38Å; T74-N76 PolarHBondContact O-OD1 2.88Å; T74-N76 PolarHBondContact OG1-OD1 2.83Å
75F98.1Very high92.7Very high1 Ų142 Ų420%0.00423%0.234CC..EExtended strand (participates in β ladder)trans-85.1128.3169.1-176.4-105.1000108.8V5 S6 L7 L8 L27 V30 L34 L36 F42 L44 Y95V5-F75 HydrophobicContact CG1-CB 4.02Å; S6-F75 PolarHBondContact O-N 3.48Å; L7-F75 HydrophobicContact CD2-CB 3.8Å; L7-F75 HydrophobicContact CD2-CG 4.28Å; L8-F75 HydrophobicContact CD1-CD1 4.25Å; L8-F75 HydrophobicContact CD1-CE1 4.49Å; L8-F75 WeakPolarHBondContact CD2-O 3.48Å; L8-F75 HydrophobicContact CG-CD1 4.3Å; L8-F75 WeakPolarHBondContact CG-O 3.37Å; L27-F75 HydrophobicContact CD1-CD2 4.21Å; L27-F75 HydrophobicContact CD1-CE2 3.84Å; V30-F75 HydrophobicContact CG1-CB 4.43Å; V30-F75 HydrophobicContact CG1-CD2 3.59Å; V30-F75 HydrophobicContact CG1-CE2 3.93Å; V30-F75 HydrophobicContact CG1-CG 4.04Å; L34-F75 HydrophobicContact CD1-CD1 3.92Å; L34-F75 HydrophobicContact CD1-CE1 3.58Å; L34-F75 HydrophobicContact CD1-CZ 3.91Å; L36-F75 HydrophobicContact CD1-CE1 3.96Å; L36-F75 HydrophobicContact CD1-CZ 3.73Å; F42-F75 HydrophobicContact CB-CD2 4.47Å; F42-F75 HydrophobicContact CB-CE1 4.22Å; F42-F75 HydrophobicContact CB-CE2 3.53Å; F42-F75 HydrophobicContact CB-CZ 3.38Å; F42-F75 HydrophobicContact CD1-CD1 4.43Å; F42-F75 AromaticContact CD1-CE1 3.49Å; F42-F75 HydrophobicContact CD1-CE1 3.49Å; F42-F75 VanDerWaalsContact CD1-CE1 3.49Å; F42-F75 HydrophobicContact CD1-CE2 4.38Å; F42-F75 AromaticContact CD1-CZ 3.47Å; F42-F75 HydrophobicContact CD1-CZ 3.47Å; F42-F75 VanDerWaalsContact CD1-CZ 3.47Å; F42-F75 HydrophobicContact CD2-CZ 4.05Å; F42-F75 HydrophobicContact CE1-CE1 4.02Å; F42-F75 HydrophobicContact CE1-CZ 4.26Å; F42-F75 AromaticContact CG-CE1 3.91Å; F42-F75 HydrophobicContact CG-CE1 3.91Å; F42-F75 HydrophobicContact CG-CE2 4.06Å; F42-F75 AromaticContact CG-CZ 3.35Å; F42-F75 HydrophobicContact CG-CZ 3.35Å; L44-F75 HydrophobicContact CD2-CB 4.26Å; L44-F75 HydrophobicContact CD2-CD2 4.06Å; F75-Y95 HydrophobicContact CE1-CD1 4.23Å
76N97.7Very high92.7Very high6 Ų643.2 Ų43.23%0.03224%0.239CC..EExtended strand (participates in β ladder)trans-143.4155.8-174.6-69109.6000111.4F42 G43 W55 T74 K78 Q99F42-N76 CarbonylContact C-O 3.33Å; F42-N76 WeakPolarHBondContact CA-O 3.46Å; G43-N76 PolarHBondContact N-O 3.43Å; G43-N76 PolarHBondContact O-N 3.3Å; W55-N76 HydrophobicContact CH2-CB 3.75Å; W55-N76 HydrophobicContact CZ3-CB 3.99Å; T74-N76 WeakPolarHBondContact CB-OD1 3.38Å; T74-N76 PolarHBondContact O-OD1 2.88Å; T74-N76 PolarHBondContact OG1-OD1 2.83Å; N76-K78 PolarHBondContact O-N 2.7Å; N76-Q99 PolarHBondContact ND2-OE1 3.42Å
77V97.9Very high92.9Very high1 Ų142.8 Ų42.81%0.00624%0.236CC..EExtended strand (participates in β ladder)trans-68.1125.4163.3-177.90000108L8 F42 W55 F79 Y80 L96 Q99L8-V77 HydrophobicContact CD1-CG2 4.3Å; F42-V77 HydrophobicContact CD1-CG2 4.06Å; F42-V77 HydrophobicContact CE1-CG2 3.75Å; W55-V77 WeakPolarHBondContact CH2-O 3.32Å; V77-F79 WeakPolarHBondContact CG1-O 3.34Å; V77-Y80 HydrophobicContact CB-CE2 4.24Å; V77-Y80 HydrophobicContact CG1-CD1 4.27Å; V77-Y80 HydrophobicContact CG1-CD2 3.92Å; V77-Y80 HydrophobicContact CG1-CE1 4.37Å; V77-Y80 HydrophobicContact CG1-CE2 3.99Å; V77-Y80 HydrophobicContact CG1-CG 4.08Å; V77-L96 HydrophobicContact CB-CD1 4.42Å; V77-L96 HydrophobicContact CG1-CD1 3.89Å; V77-L96 HydrophobicContact CG2-CD1 3.93Å; V77-Q99 HydrophobicContact CB-CB 4.18Å; V77-Q99 HydrophobicContact CB-CG 3.88Å; V77-Q99 HydrophobicContact CG2-CB 3.54Å; V77-Q99 HydrophobicContact CG2-CG 3.83Å
78K96.8Very high93.3Very high17 Ų1734.2 Ų34.27%0.07421%0.211CC..  trans-98.5-40.3177.6-175.8172.2-179.1179.50111.7Y41 W55 N76 E273Y41-K78 PolarHBondContact O-N 3.25Å; W55-K78 HydrophobicContact CD2-CD 4.05Å; W55-K78 HydrophobicContact CD2-CG 4.13Å; W55-K78 HydrophobicContact CE3-CB 4.42Å; W55-K78 HydrophobicContact CE3-CD 4.1Å; W55-K78 HydrophobicContact CE3-CG 4.28Å; W55-K78 HydrophobicContact CG-CD 4.48Å; W55-K78 VanDerWaalsContact CH2-CA 3.49Å; W55-K78 HydrophobicContact CH2-CB 3.59Å; W55-K78 HydrophobicContact CH2-CG 3.95Å; W55-K78 HydrophobicContact CZ2-CB 3.9Å; W55-K78 HydrophobicContact CZ2-CG 3.79Å; W55-K78 HydrophobicContact CZ3-CB 3.88Å; W55-K78 HydrophobicContact CZ3-CD 4.39Å; W55-K78 HydrophobicContact CZ3-CG 4.19Å; N76-K78 PolarHBondContact O-N 2.7Å; K78-E273 VanDerWaalsContact CE-OE2 3.24Å; K78-E273 WeakPolarHBondContact CE-OE2 3.06Å; K78-E273 IonicContact NZ-OE1 2.82Å; K78-E273 PolarHBondContact NZ-OE1 2.99Å; K78-E273 IonicContact NZ-OE2 2.72Å; K78-E273 PolarHBondContact NZ-OE2 3.1Å; K78-E273 VanDerWaalsContact NZ-OE2 3.14Å
79F97.7Very high93.9Very high2 Ų232 Ų321%0.00919%0.186CC..SBendtrans-121.3114.6-179.9-58.6-71.2000109.2D40 Y41 V77 P81 E273 H274 F277 F278 Y300D40-F79 VanDerWaalsContact O-CD2 3.23Å; D40-F79 WeakPolarHBondContact O-CD2 3.47Å; Y41-F79 HydrophobicContact CD1-CB 4.31Å; Y41-F79 WeakPolarHBondContact CD1-O 3.4Å; Y41-F79 PolarHBondContact O-N 3.48Å; V77-F79 WeakPolarHBondContact CG1-O 3.34Å; F79-P81 WeakPolarHBondContact O-CD 3.35Å; F79-E273 HydrophobicContact CE1-CB 4.13Å; F79-E273 HydrophobicContact CZ-CB 4.05Å; F79-H274 AromaticContact CE1-ND1 3.96Å; F79-F277 HydrophobicContact CB-CD1 3.67Å; F79-F277 HydrophobicContact CB-CE1 3.47Å; F79-F277 VanDerWaalsContact CB-CE1 3.47Å; F79-F277 HydrophobicContact CB-CG 4.41Å; F79-F277 HydrophobicContact CB-CZ 4.08Å; F79-F277 HydrophobicContact CD1-CB 4.02Å; F79-F277 AromaticContact CD1-CD1 3.79Å; F79-F277 HydrophobicContact CD1-CD1 3.79Å; F79-F277 HydrophobicContact CD1-CE1 4.46Å; F79-F277 AromaticContact CD1-CG 3.93Å; F79-F277 HydrophobicContact CD1-CG 3.93Å; F79-F277 HydrophobicContact CD2-CD1 4.1Å; F79-F277 HydrophobicContact CD2-CD2 4.02Å; F79-F277 HydrophobicContact CD2-CE1 4.21Å; F79-F277 HydrophobicContact CD2-CE2 4.15Å; F79-F277 AromaticContact CD2-CG 3.99Å; F79-F277 HydrophobicContact CD2-CG 3.99Å; F79-F277 HydrophobicContact CD2-CZ 4.23Å; F79-F277 HydrophobicContact CE1-CB 3.8Å; F79-F277 HydrophobicContact CE1-CD1 4.42Å; F79-F277 HydrophobicContact CE1-CG 4.11Å; F79-F277 HydrophobicContact CE2-CB 4.45Å; F79-F277 HydrophobicContact CE2-CD2 4.09Å; F79-F277 HydrophobicContact CE2-CG 4.16Å; F79-F277 HydrophobicContact CG-CB 4.43Å; F79-F277 AromaticContact CG-CD1 3.58Å; F79-F277 HydrophobicContact CG-CD1 3.58Å; F79-F277 HydrophobicContact CG-CD2 4.33Å; F79-F277 AromaticContact CG-CE1 3.82Å; F79-F277 HydrophobicContact CG-CE1 3.82Å; F79-F277 AromaticContact CG-CG 3.85Å; F79-F277 HydrophobicContact CG-CG 3.85Å; F79-F277 HydrophobicContact CG-CZ 4.3Å; F79-F277 HydrophobicContact CZ-CB 4.02Å; F79-F277 HydrophobicContact CZ-CD2 4.47Å; F79-F277 HydrophobicContact CZ-CG 4.21Å; F79-F278 HydrophobicContact CB-CE2 4.06Å; F79-F278 HydrophobicContact CB-CZ 3.73Å; F79-F278 AromaticContact CD1-CE2 3.89Å; F79-F278 HydrophobicContact CD1-CE2 3.89Å; F79-F278 HydrophobicContact CD1-CZ 4.43Å; F79-F278 HydrophobicContact CG-CE2 4.41Å; F79-Y300 AromaticContact CE2-CE2 3.96Å; F79-Y300 HydrophobicContact CE2-CE2 3.96Å; F79-Y300 HydrophobicContact CZ-CD2 4.46Å; F79-Y300 AromaticContact CZ-CE2 3.74Å; F79-Y300 HydrophobicContact CZ-CE2 3.74Å
80Y97.9Very high94.6Very high20 Ų2029.4 Ų29.48%0.07817%0.169CC..  trans-87115.6179.1-68.6-110000108.9V77 L96 Q99 L100 D103 Y187 F278V77-Y80 HydrophobicContact CB-CE2 4.24Å; V77-Y80 HydrophobicContact CG1-CD1 4.27Å; V77-Y80 HydrophobicContact CG1-CD2 3.92Å; V77-Y80 HydrophobicContact CG1-CE1 4.37Å; V77-Y80 HydrophobicContact CG1-CE2 3.99Å; V77-Y80 HydrophobicContact CG1-CG 4.08Å; Y80-L96 HydrophobicContact CD1-CD1 3.83Å; Y80-L96 HydrophobicContact CE1-CD1 4.23Å; Y80-Q99 HydrophobicContact CE1-CG 4.17Å; Y80-Q99 WeakPolarHBondContact OH-CG 3.45Å; Y80-L100 HydrophobicContact CD1-CD2 4.14Å; Y80-L100 HydrophobicContact CE1-CD2 3.8Å; Y80-L100 HydrophobicContact CE1-CG 4.37Å; Y80-D103 PolarHBondContact OH-OD2 3.15Å; Y80-Y187 HydrophobicContact CD1-CE2 4.22Å; Y80-F278 VanDerWaalsContact O-CZ 3.24Å; Y80-F278 WeakPolarHBondContact O-CZ 3.26Å
81P96.1Very high95.1Very high2 Ų226.3 Ų26.31%0.01315%0.149CC..  trans-62.9135.9-179.123.9-31000110.2Y41 F79 D83 P84 L87 L96 Y187Y41-P81 HydrophobicContact CE1-CB 4.03Å; Y41-P81 HydrophobicContact CE1-CG 4.43Å; F79-P81 WeakPolarHBondContact O-CD 3.35Å; P81-D83 PolarHBondContact O-N 3.15Å; P81-P84 HydrophobicContact CG-CB 4.45Å; P81-P84 HydrophobicContact CG-CG 4.43Å; P81-L87 HydrophobicContact CG-CD1 4.12Å; P81-L87 HydrophobicContact CG-CD2 4.28Å; P81-L87 HydrophobicContact CG-CG 4.27Å; P81-L96 HydrophobicContact CG-CD2 3.79Å; P81-Y187 WeakPolarHBondContact O-CE1 3.29Å; P81-Y187 PolarHBondContact O-OH 3.44Å
82P94.6Very high95.3Very high61 Ų6126.1 Ų26.140%0.39615%0.148SC..SBendtrans-66.1-26176.127.1-33.9000112.3
83D94.4Very high95.5Very high46 Ų4623.2 Ų23.225%0.24613%0.131CC..  trans-131.292.2176.1-169.824.8000109.9P81 A85 Q86 K182P81-D83 PolarHBondContact O-N 3.15Å; D83-A85 PolarHBondContact O-N 3.27Å; D83-Q86 HydrophobicContact CB-CG 4.24Å; D83-Q86 WeakPolarHBondContact O-CB 3.47Å; D83-Q86 PolarHBondContact O-N 3Å; D83-Q86 VanDerWaalsContact OD2-CD 3.27Å; D83-Q86 WeakPolarHBondContact OD2-CG 3.38Å; D83-Q86 PolarHBondContact OD2-NE2 3.4Å; D83-K182 IonicContact OD1-NZ 2.68Å; D83-K182 PolarHBondContact OD1-NZ 3.38Å
84P93.8Very high95.5Very high0 Ų023 Ų230%013%0.13CC..G310 helixtrans-64.4-20.9-177.4-22.634.8000114.3P81 Q86 L87 L96 L178 K182P81-P84 HydrophobicContact CG-CB 4.45Å; P81-P84 HydrophobicContact CG-CG 4.43Å; P84-Q86 PolarHBondContact O-N 3Å; P84-Q86 VanDerWaalsContact O-N 3.17Å; P84-L87 WeakPolarHBondContact O-CB 3.27Å; P84-L87 WeakPolarHBondContact O-CG 3.39Å; P84-L87 PolarHBondContact O-N 3.48Å; P84-L87 VanDerWaalsContact O-N 3.08Å; P84-L96 HydrophobicContact CB-CD2 4.14Å; P84-L96 HydrophobicContact CG-CD2 4.32Å; P84-L178 HydrophobicContact CB-CB 3.8Å; P84-L178 HydrophobicContact CB-CD1 3.92Å; P84-L178 HydrophobicContact CB-CG 4.3Å; P84-L178 HydrophobicContact CG-CB 4.07Å; P84-K182 HydrophobicContact CG-CB 4.43Å; P84-K182 HydrophobicContact CG-CD 4.39Å
85A91Very high95.5Very high51 Ų5122.5 Ų22.542%0.42113%0.125SC..G310 helixtrans-60.9-19.8173.900000113.2D83 L87 L175D83-A85 PolarHBondContact O-N 3.27Å; A85-L87 VanDerWaalsContact C-N 3.34Å; A85-L175 HydrophobicContact CB-CD1 4.17Å
86Q91.1Very high95.5Very high84 Ų8422.7 Ų22.739%0.39313%0.126SC..G310 helixtrans-86.4-3.3177.7-64.6171.3-8.800113.9D83 P84D83-Q86 HydrophobicContact CB-CG 4.24Å; D83-Q86 WeakPolarHBondContact O-CB 3.47Å; D83-Q86 PolarHBondContact O-N 3Å; D83-Q86 VanDerWaalsContact OD2-CD 3.27Å; D83-Q86 WeakPolarHBondContact OD2-CG 3.38Å; D83-Q86 PolarHBondContact OD2-NE2 3.4Å; P84-Q86 PolarHBondContact O-N 3Å; P84-Q86 VanDerWaalsContact O-N 3.17Å
87L94.8Very high95.5Very high8 Ų822.4 Ų22.44%0.04212%0.124CC..  trans-65.5141.2167.6-65.5174.4000108.6Y41 P81 P84 A85 T92 R93 L96Y41-L87 HydrophobicContact CD2-CD2 3.83Å; Y41-L87 HydrophobicContact CE1-CD2 4.39Å; Y41-L87 HydrophobicContact CE2-CD2 3.33Å; P81-L87 HydrophobicContact CG-CD1 4.12Å; P81-L87 HydrophobicContact CG-CD2 4.28Å; P81-L87 HydrophobicContact CG-CG 4.27Å; P84-L87 WeakPolarHBondContact O-CB 3.27Å; P84-L87 WeakPolarHBondContact O-CG 3.39Å; P84-L87 PolarHBondContact O-N 3.48Å; P84-L87 VanDerWaalsContact O-N 3.08Å; A85-L87 VanDerWaalsContact C-N 3.34Å; L87-T92 HydrophobicContact CD1-CG2 3.97Å; L87-T92 HydrophobicContact CD2-CG2 3.87Å; L87-T92 HydrophobicContact CG-CG2 4.38Å; L87-R93 HydrophobicContact CB-CG 4.16Å; L87-R93 HydrophobicContact CD1-CG 4.01Å; L87-R93 PolarHBondContact O-NH1 3.14Å; L87-L96 HydrophobicContact CD1-CD2 4.05Å
88T93.8Very high95.5Very high67 Ų6723 Ų2341%0.41113%0.127SC..  trans-84.3-44.5-177-54.20000110.3E38 R93 S312E38-T88 PolarHBondContact OE1-N 3.18Å; E38-T88 PolarHBondContact OE2-N 2.92Å; T88-R93 PolarHBondContact O-NH2 3.22Å; T88-S312 WeakPolarHBondContact OG1-CB 3.47Å
89E93.8Very high95.5Very high10 Ų1022.1 Ų22.15%0.04712%0.124CC..  trans-98.1139.1-170.5-48.9-160.896.700113.5L37 E38 I91 T92 R93 I315 R317L37-E89 WeakPolarHBondContact CB-OE2 3.37Å; L37-E89 PolarHBondContact N-OE2 2.89Å; E38-E89 PolarHBondContact OE2-N 3.46Å; E89-I91 HydrophobicContact CB-CG2 3.84Å; E89-I91 PolarHBondContact O-N 2.77Å; E89-T92 WeakPolarHBondContact O-CB 3.36Å; E89-T92 PolarHBondContact O-N 2.79Å; E89-T92 VanDerWaalsContact O-N 3.16Å; E89-R93 PolarHBondContact O-N 3.08Å; E89-I315 HydrophobicContact CG-CD1 4.13Å; E89-R317 IonicContact OE1-CZ 3.05Å; E89-R317 IonicContact OE1-NE 3.63Å; E89-R317 PolarHBondContact OE1-NE 2.8Å; E89-R317 IonicContact OE1-NH2 2.73Å; E89-R317 PolarHBondContact OE1-NH2 3.06Å; E89-R317 IonicContact OE2-NH2 2.63Å; E89-R317 PolarHBondContact OE2-NH2 3.39Å; E89-R317 VanDerWaalsContact OE2-NH2 3.08Å
90D93.6Very high95.6Very high45 Ų4522 Ų2224%0.24112%0.123CC..Hα-helixtrans-60.2-36.2174.3-70.9-31.7000112.2T92 R93 Y94 A171 F322D90-T92 VanDerWaalsContact C-N 3.31Å; D90-T92 PolarHBondContact O-N 2.86Å; D90-R93 WeakPolarHBondContact O-CB 3.47Å; D90-R93 PolarHBondContact O-N 3.3Å; D90-R93 IonicContact OD1-CZ 3.22Å; D90-R93 VanDerWaalsContact OD1-CZ 3.31Å; D90-R93 IonicContact OD1-NE 2.7Å; D90-R93 PolarHBondContact OD1-NE 2.9Å; D90-R93 IonicContact OD1-NH2 2.67Å; D90-R93 PolarHBondContact OD1-NH2 3.29Å; D90-Y94 WeakPolarHBondContact O-CB 3.17Å; D90-Y94 PolarHBondContact O-N 2.82Å; D90-A171 HydrophobicContact CB-CB 4.43Å; D90-F322 HydrophobicContact CB-CE1 4.33Å
91I95Very high95.5Very high4 Ų422.6 Ų22.62%0.02113%0.125CC..Hα-helixtrans-63.1-38.9177.7-168.6165.8000111.1L34 L36 E89 R93 Y94 Y95 P320 F322L34-I91 WeakPolarHBondContact O-CD1 3.19Å; L36-I91 HydrophobicContact CD2-CB 4.34Å; L36-I91 HydrophobicContact CD2-CD1 4.42Å; L36-I91 HydrophobicContact CD2-CG1 3.88Å; L36-I91 HydrophobicContact CD2-CG2 3.88Å; E89-I91 HydrophobicContact CB-CG2 3.84Å; E89-I91 PolarHBondContact O-N 2.77Å; I91-R93 PolarHBondContact O-N 2.83Å; I91-Y94 PolarHBondContact O-N 2.9Å; I91-Y95 HydrophobicContact CD1-CE2 4.21Å; I91-Y95 HydrophobicContact CG1-CD2 3.83Å; I91-Y95 HydrophobicContact CG1-CE2 3.77Å; I91-Y95 VanDerWaalsContact O-CD2 3.3Å; I91-Y95 WeakPolarHBondContact O-CD2 3.43Å; I91-Y95 PolarHBondContact O-N 2.89Å; I91-P320 HydrophobicContact CB-CG 4.06Å; I91-P320 HydrophobicContact CG2-CG 3.62Å; I91-F322 VanDerWaalsContact CA-CE1 3.49Å; I91-F322 HydrophobicContact CB-CD1 3.69Å; I91-F322 HydrophobicContact CB-CE1 3.6Å; I91-F322 HydrophobicContact CB-CG 4.48Å; I91-F322 HydrophobicContact CB-CZ 4.32Å; I91-F322 HydrophobicContact CD1-CB 4.06Å; I91-F322 HydrophobicContact CD1-CD1 3.92Å; I91-F322 HydrophobicContact CD1-CG 4.06Å; I91-F322 HydrophobicContact CG1-CD1 3.82Å; I91-F322 HydrophobicContact CG1-CE1 4.08Å; I91-F322 HydrophobicContact CG1-CG 4.12Å
92T96.6Very high95.5Very high2 Ų225.3 Ų25.31%0.01214%0.138CC..Hα-helixtrans-64.4-43.7176.5-50.50000111.1E38 Y41 F42 L87 E89 D90 Y94 Y95 L96E38-T92 HydrophobicContact CB-CG2 3.89Å; E38-T92 WeakPolarHBondContact OE2-CB 3.5Å; E38-T92 PolarHBondContact OE2-OG1 2.82Å; Y41-T92 HydrophobicContact CD2-CG2 4.44Å; F42-T92 HydrophobicContact CE2-CG2 4.01Å; F42-T92 HydrophobicContact CZ-CG2 4.15Å; L87-T92 HydrophobicContact CD1-CG2 3.97Å; L87-T92 HydrophobicContact CD2-CG2 3.87Å; L87-T92 HydrophobicContact CG-CG2 4.38Å; E89-T92 WeakPolarHBondContact O-CB 3.36Å; E89-T92 PolarHBondContact O-N 2.79Å; E89-T92 VanDerWaalsContact O-N 3.16Å; D90-T92 VanDerWaalsContact C-N 3.31Å; D90-T92 PolarHBondContact O-N 2.86Å; T92-Y94 VanDerWaalsContact C-N 3.35Å; T92-Y95 PolarHBondContact O-N 2.85Å; T92-L96 PolarHBondContact O-N 3.09Å
93R96.9Very high95.6Very high28 Ų2822.8 Ų22.811%0.10612%0.121CC..Hα-helixtrans-58.9-46.3173.4-75.8-176.6-84.4-78.9-1.1111.3L87 T88 E89 D90 I91 Y95 L96 C97 L178L87-R93 HydrophobicContact CB-CG 4.16Å; L87-R93 HydrophobicContact CD1-CG 4.01Å; L87-R93 PolarHBondContact O-NH1 3.14Å; T88-R93 PolarHBondContact O-NH2 3.22Å; E89-R93 PolarHBondContact O-N 3.08Å; D90-R93 WeakPolarHBondContact O-CB 3.47Å; D90-R93 PolarHBondContact O-N 3.3Å; D90-R93 IonicContact OD1-CZ 3.22Å; D90-R93 VanDerWaalsContact OD1-CZ 3.31Å; D90-R93 IonicContact OD1-NE 2.7Å; D90-R93 PolarHBondContact OD1-NE 2.9Å; D90-R93 IonicContact OD1-NH2 2.67Å; D90-R93 PolarHBondContact OD1-NH2 3.29Å; I91-R93 PolarHBondContact O-N 2.83Å; R93-Y95 PolarHBondContact O-N 2.82Å; R93-L96 WeakPolarHBondContact O-CB 3.4Å; R93-L96 PolarHBondContact O-N 3.27Å; R93-L96 VanDerWaalsContact O-N 3.13Å; R93-C97 PolarHBondContact O-N 3.41Å; R93-C97 PolarHBondContact O-SG 3.33Å; R93-C97 VanDerWaalsContact O-SG 3.41Å; R93-L178 HydrophobicContact CB-CD1 3.74Å; R93-L178 HydrophobicContact CG-CD1 3.8Å
94Y96.8Very high95.7Very high2 Ų220.9 Ų20.91%0.00811%0.111CC..Hα-helixtrans-59.4-47.7179.6179.2-116.9000112.3D90 I91 T92 L96 C97 L98 E127 F322 R324 T325D90-Y94 WeakPolarHBondContact O-CB 3.17Å; D90-Y94 PolarHBondContact O-N 2.82Å; I91-Y94 PolarHBondContact O-N 2.9Å; T92-Y94 VanDerWaalsContact C-N 3.35Å; Y94-L96 VanDerWaalsContact C-N 3.27Å; Y94-L96 PolarHBondContact O-N 3.26Å; Y94-C97 WeakPolarHBondContact O-CA 3.42Å; Y94-C97 VanDerWaalsContact O-CB 3.29Å; Y94-C97 WeakPolarHBondContact O-CB 3.31Å; Y94-C97 PolarHBondContact O-N 3.02Å; Y94-C97 VanDerWaalsContact O-N 3.08Å; Y94-L98 HydrophobicContact CD1-CD1 4.1Å; Y94-L98 HydrophobicContact CD1-CG 4.48Å; Y94-L98 HydrophobicContact CE1-CD1 3.62Å; Y94-L98 HydrophobicContact CE1-CD2 4.46Å; Y94-L98 HydrophobicContact CE1-CG 4.12Å; Y94-L98 HydrophobicContact CE2-CD2 4.2Å; Y94-L98 HydrophobicContact CE2-CG 4.29Å; Y94-L98 WeakPolarHBondContact O-CG 3.34Å; Y94-L98 PolarHBondContact O-N 3.36Å; Y94-E127 VanDerWaalsContact CE2-OE1 3.26Å; Y94-E127 WeakPolarHBondContact CE2-OE1 3.09Å; Y94-E127 PolarHBondContact OH-OE1 3.22Å; Y94-E127 PolarHBondContact OH-OE2 3.43Å; Y94-F322 AromaticContact CD1-CD2 3.85Å; Y94-F322 HydrophobicContact CD1-CD2 3.85Å; Y94-F322 AromaticContact CD1-CE2 3.31Å; Y94-F322 HydrophobicContact CD1-CE2 3.31Å; Y94-F322 HydrophobicContact CD1-CZ 4.15Å; Y94-F322 HydrophobicContact CD2-CE2 4.19Å; Y94-F322 HydrophobicContact CE1-CD2 4.19Å; Y94-F322 AromaticContact CE1-CE2 3.93Å; Y94-F322 HydrophobicContact CE1-CE2 3.93Å; Y94-F322 HydrophobicContact CG-CD2 4.43Å; Y94-F322 AromaticContact CG-CE2 3.46Å; Y94-F322 HydrophobicContact CG-CE2 3.46Å; Y94-F322 VanDerWaalsContact CG-CE2 3.46Å; Y94-F322 AromaticContact CG-CZ 3.97Å; Y94-F322 HydrophobicContact CG-CZ 3.97Å; Y94-R324 HydrophobicContact CE2-CB 4.37Å; Y94-R324 HydrophobicContact CE2-CG 4.22Å; Y94-R324 WeakPolarHBondContact OH-CA 3.27Å; Y94-T325 PolarHBondContact OH-N 3.21Å
95Y97.4Very high95.8Very high16 Ų1623.2 Ų23.26%0.06312%0.124CC..Hα-helixtrans-64.4-31.5176.4-85.6-85.5000112.8L8 L34 L36 F75 I91 T92 R93 L98 Q99L8-Y95 HydrophobicContact CB-CD1 3.94Å; L8-Y95 HydrophobicContact CB-CE1 4.3Å; L8-Y95 HydrophobicContact CD1-CD1 3.99Å; L8-Y95 WeakPolarHBondContact CD1-O 3.29Å; L8-Y95 HydrophobicContact CG-CD1 4.44Å; L34-Y95 HydrophobicContact CD1-CE1 3.89Å; L34-Y95 HydrophobicContact CD2-CE1 4.37Å; L34-Y95 WeakPolarHBondContact CD2-OH 3.11Å; L36-Y95 HydrophobicContact CD1-CD2 4.21Å; L36-Y95 HydrophobicContact CD1-CE2 4.48Å; L36-Y95 HydrophobicContact CD1-CG 4.38Å; L36-Y95 HydrophobicContact CD2-CD2 4.01Å; L36-Y95 HydrophobicContact CG-CD2 4.46Å; F75-Y95 HydrophobicContact CE1-CD1 4.23Å; I91-Y95 HydrophobicContact CD1-CE2 4.21Å; I91-Y95 HydrophobicContact CG1-CD2 3.83Å; I91-Y95 HydrophobicContact CG1-CE2 3.77Å; I91-Y95 VanDerWaalsContact O-CD2 3.3Å; I91-Y95 WeakPolarHBondContact O-CD2 3.43Å; I91-Y95 PolarHBondContact O-N 2.89Å; T92-Y95 PolarHBondContact O-N 2.85Å; R93-Y95 PolarHBondContact O-N 2.82Å; Y95-L98 HydrophobicContact CD1-CD1 4.24Å; Y95-L98 HydrophobicContact CE1-CD1 4.37Å; Y95-L98 PolarHBondContact O-N 3.38Å; Y95-Q99 PolarHBondContact O-N 2.88Å; Y95-Q99 VanDerWaalsContact O-N 3.1Å
96L98.1Very high95.9Very high4 Ų424 Ų242%0.02113%0.131CC..Hα-helixtrans-66.3-42170.8-176.960000111.8V77 Y80 P81 P84 L87 T92 R93 Y94 Q99 L100 L178V77-L96 HydrophobicContact CB-CD1 4.42Å; V77-L96 HydrophobicContact CG1-CD1 3.89Å; V77-L96 HydrophobicContact CG2-CD1 3.93Å; Y80-L96 HydrophobicContact CD1-CD1 3.83Å; Y80-L96 HydrophobicContact CE1-CD1 4.23Å; P81-L96 HydrophobicContact CG-CD2 3.79Å; P84-L96 HydrophobicContact CB-CD2 4.14Å; P84-L96 HydrophobicContact CG-CD2 4.32Å; L87-L96 HydrophobicContact CD1-CD2 4.05Å; T92-L96 PolarHBondContact O-N 3.09Å; R93-L96 WeakPolarHBondContact O-CB 3.4Å; R93-L96 PolarHBondContact O-N 3.27Å; R93-L96 VanDerWaalsContact O-N 3.13Å; Y94-L96 VanDerWaalsContact C-N 3.27Å; Y94-L96 PolarHBondContact O-N 3.26Å; L96-Q99 PolarHBondContact O-N 3.02Å; L96-L100 HydrophobicContact CD1-CD1 4.34Å; L96-L100 HydrophobicContact CG-CD1 4.08Å; L96-L100 WeakPolarHBondContact O-CG 3.32Å; L96-L100 PolarHBondContact O-N 3.43Å; L96-L178 HydrophobicContact CB-CD2 4.17Å; L96-L178 HydrophobicContact CD2-CD1 4.24Å; L96-L178 HydrophobicContact CD2-CD2 3.66Å; L96-L178 HydrophobicContact CG-CD2 3.61Å
97C97.9Very high96Very high0 Ų022 Ų220%013%0.134CC..Hα-helixtrans-57.7-48172.3-68.50000111.3R93 Y94 Q99 L100 R101 F177R93-C97 PolarHBondContact O-N 3.41Å; R93-C97 PolarHBondContact O-SG 3.33Å; R93-C97 VanDerWaalsContact O-SG 3.41Å; Y94-C97 WeakPolarHBondContact O-CA 3.42Å; Y94-C97 VanDerWaalsContact O-CB 3.29Å; Y94-C97 WeakPolarHBondContact O-CB 3.31Å; Y94-C97 PolarHBondContact O-N 3.02Å; Y94-C97 VanDerWaalsContact O-N 3.08Å; C97-Q99 VanDerWaalsContact C-N 3.33Å; C97-Q99 PolarHBondContact O-N 2.93Å; C97-L100 PolarHBondContact O-N 3.41Å; C97-L100 VanDerWaalsContact O-N 3.12Å; C97-R101 VanDerWaalsContact O-CG 3.26Å; C97-R101 WeakPolarHBondContact O-CG 3.37Å; C97-R101 PolarHBondContact O-N 2.86Å; C97-F177 HydrophobicContact CB-CD1 4.23Å; C97-F177 HydrophobicContact CB-CE1 4.37Å
98L97.3Very high95.8Very high13 Ų1326.4 Ų26.47%0.06815%0.149CC..Hα-helixtrans-56.9-45.5178.2-68.7179.5000112L8 D9 Y94 Y95 L100 R101 Q102L8-L98 HydrophobicContact CB-CB 3.94Å; L8-L98 HydrophobicContact CB-CD1 4.18Å; D9-L98 HydrophobicContact CB-CD1 3.89Å; Y94-L98 HydrophobicContact CD1-CD1 4.1Å; Y94-L98 HydrophobicContact CD1-CG 4.48Å; Y94-L98 HydrophobicContact CE1-CD1 3.62Å; Y94-L98 HydrophobicContact CE1-CD2 4.46Å; Y94-L98 HydrophobicContact CE1-CG 4.12Å; Y94-L98 HydrophobicContact CE2-CD2 4.2Å; Y94-L98 HydrophobicContact CE2-CG 4.29Å; Y94-L98 WeakPolarHBondContact O-CG 3.34Å; Y94-L98 PolarHBondContact O-N 3.36Å; Y95-L98 HydrophobicContact CD1-CD1 4.24Å; Y95-L98 HydrophobicContact CE1-CD1 4.37Å; Y95-L98 PolarHBondContact O-N 3.38Å; L98-L100 PolarHBondContact O-N 2.86Å; L98-R101 PolarHBondContact O-N 3.32Å; L98-Q102 WeakPolarHBondContact O-CG 3.37Å; L98-Q102 PolarHBondContact O-N 2.89Å; L98-Q102 VanDerWaalsContact O-N 3.08Å
99Q97.8Very high95.9Very high0 Ų023.3 Ų23.30%013%0.131CC..Hα-helixtrans-60.8-45.6175.6-178.267.978.900111.9L8 N76 V77 Y80 Y95 L96 C97 R101 Q102 D103L8-Q99 HydrophobicContact CD1-CB 4.11Å; L8-Q99 HydrophobicContact CD2-CB 4.2Å; N76-Q99 PolarHBondContact ND2-OE1 3.42Å; V77-Q99 HydrophobicContact CB-CB 4.18Å; V77-Q99 HydrophobicContact CB-CG 3.88Å; V77-Q99 HydrophobicContact CG2-CB 3.54Å; V77-Q99 HydrophobicContact CG2-CG 3.83Å; Y80-Q99 HydrophobicContact CE1-CG 4.17Å; Y80-Q99 WeakPolarHBondContact OH-CG 3.45Å; Y95-Q99 PolarHBondContact O-N 2.88Å; Y95-Q99 VanDerWaalsContact O-N 3.1Å; L96-Q99 PolarHBondContact O-N 3.02Å; C97-Q99 VanDerWaalsContact C-N 3.33Å; C97-Q99 PolarHBondContact O-N 2.93Å; Q99-R101 PolarHBondContact O-N 3.44Å; Q99-Q102 WeakPolarHBondContact O-CB 3.4Å; Q99-Q102 PolarHBondContact O-N 2.74Å; Q99-D103 PolarHBondContact NE2-OD1 2.88Å; Q99-D103 PolarHBondContact O-N 2.73Å
100L98.2Very high96Very high0 Ų026.7 Ų26.70%015%0.153CC..Hα-helixtrans-67.2-36.1-178.7-70164.5000112.3Y80 L96 C97 L98 Q102 D103 I104 L109 F177 L178 A181 Y187Y80-L100 HydrophobicContact CD1-CD2 4.14Å; Y80-L100 HydrophobicContact CE1-CD2 3.8Å; Y80-L100 HydrophobicContact CE1-CG 4.37Å; L96-L100 HydrophobicContact CD1-CD1 4.34Å; L96-L100 HydrophobicContact CG-CD1 4.08Å; L96-L100 WeakPolarHBondContact O-CG 3.32Å; L96-L100 PolarHBondContact O-N 3.43Å; C97-L100 PolarHBondContact O-N 3.41Å; C97-L100 VanDerWaalsContact O-N 3.12Å; L98-L100 PolarHBondContact O-N 2.86Å; L100-Q102 VanDerWaalsContact C-N 3.35Å; L100-D103 WeakPolarHBondContact O-CB 3.41Å; L100-D103 PolarHBondContact O-N 3.39Å; L100-D103 VanDerWaalsContact O-N 3.11Å; L100-I104 VanDerWaalsContact O-CG1 3.32Å; L100-I104 WeakPolarHBondContact O-CG1 3.42Å; L100-I104 PolarHBondContact O-N 2.97Å; L100-L109 HydrophobicContact CD2-CD2 3.75Å; L100-F177 HydrophobicContact CB-CE1 3.75Å; L100-F177 HydrophobicContact CB-CZ 4.1Å; L100-F177 HydrophobicContact CD1-CE1 3.93Å; L100-L178 HydrophobicContact CD1-CD2 3.47Å; L100-L178 VanDerWaalsContact CD1-CD2 3.47Å; L100-A181 HydrophobicContact CD1-CB 4.04Å; L100-Y187 HydrophobicContact CD1-CD2 4.42Å; L100-Y187 HydrophobicContact CD1-CE2 3.88Å; L100-Y187 HydrophobicContact CD2-CD2 3.72Å; L100-Y187 HydrophobicContact CD2-CE2 3.82Å; L100-Y187 HydrophobicContact CG-CE2 4.47Å
101R97.3Very high96.1Very high32 Ų3226.1 Ų26.112%0.12115%0.152CC..Hα-helixtrans-59.6-45.9171.5-68.2169.6-167.6175.24.7110.8C97 L98 Q99 D103 I104 V105 T123 S126 E127 D174 F177C97-R101 VanDerWaalsContact O-CG 3.26Å; C97-R101 WeakPolarHBondContact O-CG 3.37Å; C97-R101 PolarHBondContact O-N 2.86Å; L98-R101 PolarHBondContact O-N 3.32Å; Q99-R101 PolarHBondContact O-N 3.44Å; R101-D103 VanDerWaalsContact C-N 3.29Å; R101-D103 PolarHBondContact O-N 3.5Å; R101-I104 PolarHBondContact O-N 3.05Å; R101-V105 WeakPolarHBondContact O-CG2 3.29Å; R101-V105 PolarHBondContact O-N 2.72Å; R101-T123 PolarHBondContact NE-OG1 2.94Å; R101-S126 PolarHBondContact NH2-OG 3.21Å; R101-E127 IonicContact CZ-OE1 3.77Å; R101-E127 IonicContact NH1-OE1 2.56Å; R101-E127 PolarHBondContact NH1-OE1 3.14Å; R101-E127 IonicContact NH2-OE1 2.82Å; R101-D174 IonicContact NH2-OD1 2.67Å; R101-F177 HydrophobicContact CG-CE2 4.15Å; R101-F177 HydrophobicContact CG-CZ 3.98Å
102Q95.6Very high96.2Very high59 Ų5929 Ų2928%0.27617%0.173SC..Hα-helixtrans-61.1-38.6172.6-66.9178.7200112L8 L98 Q99 L100 A106L8-Q102 PolarHBondContact O-NE2 2.98Å; L98-Q102 WeakPolarHBondContact O-CG 3.37Å; L98-Q102 PolarHBondContact O-N 2.89Å; L98-Q102 VanDerWaalsContact O-N 3.08Å; Q99-Q102 WeakPolarHBondContact O-CB 3.4Å; Q99-Q102 PolarHBondContact O-N 2.74Å; L100-Q102 VanDerWaalsContact C-N 3.35Å; Q102-A106 WeakPolarHBondContact O-CB 3.18Å; Q102-A106 PolarHBondContact O-N 2.6Å
103D96.3Very high96.2Very high7 Ų733.3 Ų33.34%0.03719%0.192CC..Hα-helixtrans-64.8-39178.2-61.3-5.7000111.5Y80 Q99 L100 R101 G107 R108 L109Y80-D103 PolarHBondContact OH-OD2 3.15Å; Q99-D103 PolarHBondContact NE2-OD1 2.88Å; Q99-D103 PolarHBondContact O-N 2.73Å; L100-D103 WeakPolarHBondContact O-CB 3.41Å; L100-D103 PolarHBondContact O-N 3.39Å; L100-D103 VanDerWaalsContact O-N 3.11Å; R101-D103 VanDerWaalsContact C-N 3.29Å; R101-D103 PolarHBondContact O-N 3.5Å; D103-G107 PolarHBondContact O-N 3.34Å; D103-R108 HydrophobicContact CB-CB 4.32Å; D103-R108 VanDerWaalsContact CG-NH1 3.27Å; D103-R108 WeakPolarHBondContact O-CA 3.46Å; D103-R108 PolarHBondContact O-N 2.93Å; D103-R108 IonicContact OD1-CZ 3.94Å; D103-R108 IonicContact OD1-NH1 3.77Å; D103-R108 PolarHBondContact OD1-NH1 3.32Å; D103-R108 IonicContact OD1-NH2 3.67Å; D103-R108 PolarHBondContact OD1-NH2 3.4Å; D103-R108 IonicContact OD2-NH1 2.74Å; D103-L109 HydrophobicContact CB-CB 3.87Å; D103-L109 PolarHBondContact O-N 3.36Å
104I97.4Very high96.2Very high7 Ų735.2 Ų35.24%0.03621%0.214CC..Hα-helixtrans-65.2-53.4174.9-68.3166.7000110.3L100 R101 A106 G107 L109 L116 L119 L146 P148 F177L100-I104 VanDerWaalsContact O-CG1 3.32Å; L100-I104 WeakPolarHBondContact O-CG1 3.42Å; L100-I104 PolarHBondContact O-N 2.97Å; R101-I104 PolarHBondContact O-N 3.05Å; I104-A106 VanDerWaalsContact C-N 3.27Å; I104-A106 PolarHBondContact O-N 2.88Å; I104-G107 PolarHBondContact O-N 3.07Å; I104-L109 HydrophobicContact CD1-CD2 4.48Å; I104-L109 HydrophobicContact CG1-CB 4.07Å; I104-L109 HydrophobicContact CG1-CD2 3.99Å; I104-L109 HydrophobicContact CG1-CG 4.17Å; I104-L116 HydrophobicContact CG2-CD2 3.46Å; I104-L116 VanDerWaalsContact CG2-CD2 3.46Å; I104-L119 HydrophobicContact CD1-CD1 3.8Å; I104-L146 WeakPolarHBondContact CG2-O 3.24Å; I104-P148 WeakPolarHBondContact O-CD 3.35Å; I104-P148 VanDerWaalsContact O-CG 3.29Å; I104-P148 WeakPolarHBondContact O-CG 3.44Å; I104-F177 HydrophobicContact CD1-CZ 4.24Å
105V95.4Very high96.3Very high48 Ų4836.8 Ų36.829%0.29122%0.223SC..Hα-helixtrans-62.6-34.5-178173.30000112R101 G107 K145 P148R101-V105 WeakPolarHBondContact O-CG2 3.29Å; R101-V105 PolarHBondContact O-N 2.72Å; V105-G107 PolarHBondContact O-N 2.92Å; V105-K145 HydrophobicContact CG2-CB 4.27Å; V105-K145 WeakPolarHBondContact CG2-O 3.11Å; V105-P148 WeakPolarHBondContact O-CG 3.41Å
106A93Very high96.4Very high68 Ų6837.2 Ų37.256%0.56223%0.227SC*.THydrogen-bonded Turntrans-78.4-3.7175.100000113.8Q102 I104 R108Q102-A106 WeakPolarHBondContact O-CB 3.18Å; Q102-A106 PolarHBondContact O-N 2.6Å; I104-A106 VanDerWaalsContact C-N 3.27Å; I104-A106 PolarHBondContact O-N 2.88Å; A106-R108 HydrophobicContact CB-CG 4.45Å; A106-R108 PolarHBondContact O-N 3.4Å
107G92.5Very high96.4Very high43 Ų4337.1 Ų37.144%0.44323%0.226SC..THydrogen-bonded Turntrans71.812.7-176.500000114.7D103 I104 V105D103-G107 PolarHBondContact O-N 3.34Å; I104-G107 PolarHBondContact O-N 3.07Å; V105-G107 PolarHBondContact O-N 2.92Å
108R92.3Very high96.4Very high99 Ų9939.5 Ų39.537%0.37424%0.239SC..SBendtrans-77.1-27175-72.6-168.5-75118.9-1.4112.5D103 A106 P110D103-R108 HydrophobicContact CB-CB 4.32Å; D103-R108 VanDerWaalsContact CG-NH1 3.27Å; D103-R108 WeakPolarHBondContact O-CA 3.46Å; D103-R108 PolarHBondContact O-N 2.93Å; D103-R108 IonicContact OD1-CZ 3.94Å; D103-R108 IonicContact OD1-NH1 3.77Å; D103-R108 PolarHBondContact OD1-NH1 3.32Å; D103-R108 IonicContact OD1-NH2 3.67Å; D103-R108 PolarHBondContact OD1-NH2 3.4Å; D103-R108 IonicContact OD2-NH1 2.74Å; A106-R108 HydrophobicContact CB-CG 4.45Å; A106-R108 PolarHBondContact O-N 3.4Å; R108-P110 WeakPolarHBondContact O-CD 3.33Å
109L95.8Very high96.5Very high3 Ų339.1 Ų39.12%0.01624%0.237CC..SBendtrans-116.585.1174-172.957.9000109.6L100 D103 I104 C111 L184 M186L100-L109 HydrophobicContact CD2-CD2 3.75Å; D103-L109 HydrophobicContact CB-CB 3.87Å; D103-L109 PolarHBondContact O-N 3.36Å; I104-L109 HydrophobicContact CD1-CD2 4.48Å; I104-L109 HydrophobicContact CG1-CB 4.07Å; I104-L109 HydrophobicContact CG1-CD2 3.99Å; I104-L109 HydrophobicContact CG1-CG 4.17Å; L109-C111 PolarHBondContact O-N 3.31Å; L109-C111 PolarHBondContact O-SG 2.81Å; L109-L184 HydrophobicContact CD1-CB 3.73Å; L109-L184 HydrophobicContact CD1-CD1 3.85Å; L109-L184 HydrophobicContact CD1-CG 4.46Å; L109-L184 HydrophobicContact CD2-CD1 3.91Å; L109-L184 HydrophobicContact CG-CD1 3.76Å; L109-M186 HydrophobicContact CD1-CB 3.96Å
110P94.4Very high96.5Very high81 Ų8139.2 Ų39.253%0.52624%0.238SC..  trans-63.3133.8-179.3-20.533.3000111.1R108 M186R108-P110 WeakPolarHBondContact O-CD 3.33Å; P110-M186 HydrophobicContact CG-CG 4.43Å
111C96.2Very high96.5Very high33 Ų3339.2 Ų39.222%0.22324%0.238CC..  trans-128.3146.7-179.3-67.50000110.1L109 T115 L116 L184L109-C111 PolarHBondContact O-N 3.31Å; L109-C111 PolarHBondContact O-SG 2.81Å; C111-T115 HydrophobicContact CB-CG2 3.97Å; C111-L116 HydrophobicContact CB-CD2 3.61Å; C111-L116 HydrophobicContact CB-CG 3.64Å; C111-L184 VanDerWaalsContact SG-CD1 3.56Å
112S96.3Very high96.6Very high65 Ų6538.9 Ų38.946%0.45524%0.237SC..  trans-70.2164.5167.177.20000110.5A114 T115 L116S112-A114 VanDerWaalsContact C-N 3.33Å; S112-A114 PolarHBondContact O-N 2.93Å; S112-T115 WeakPolarHBondContact O-CB 3.43Å; S112-T115 PolarHBondContact O-N 2.88Å; S112-T115 WeakPolarHBondContact OG-CB 3.44Å; S112-T115 PolarHBondContact OG-N 2.78Å; S112-T115 VanDerWaalsContact OG-N 3.14Å; S112-T115 PolarHBondContact OG-OG1 2.82Å; S112-L116 WeakPolarHBondContact O-CG 3.32Å; S112-L116 PolarHBondContact O-N 3.33Å
113F97.6Very high96.7Very high92 Ų9236.4 Ų36.440%0.40423%0.226SC..Hα-helixtrans-54.5-48.3174.3178.2-91.2000112.2T115 L116 A117 E153 L154 K157F113-T115 VanDerWaalsContact C-N 3.3Å; F113-T115 PolarHBondContact O-N 2.86Å; F113-L116 WeakPolarHBondContact O-CB 3.46Å; F113-L116 PolarHBondContact O-N 2.78Å; F113-L116 VanDerWaalsContact O-N 3.17Å; F113-A117 PolarHBondContact O-N 2.84Å; F113-E153 HydrophobicContact CE2-CG 4.45Å; F113-E153 HydrophobicContact CZ-CG 4.05Å; F113-L154 HydrophobicContact CD2-CD1 4.42Å; F113-L154 HydrophobicContact CE2-CB 3.81Å; F113-L154 HydrophobicContact CE2-CD1 4.14Å; F113-L154 HydrophobicContact CZ-CB 4.44Å; F113-L154 HydrophobicContact CZ-CD1 4.5Å; F113-K157 HydrophobicContact CE1-CG 4.49Å; F113-K157 HydrophobicContact CZ-CB 4.38Å
114A97.8Very high96.7Very high68 Ų6836.1 Ų36.156%0.56222%0.224SC*.Hα-helixtrans-61.4-40179.200000112.1S112 A117 L118S112-A114 VanDerWaalsContact C-N 3.33Å; S112-A114 PolarHBondContact O-N 2.93Å; A114-A117 PolarHBondContact O-N 2.56Å; A114-L118 WeakPolarHBondContact O-CB 3.29Å; A114-L118 PolarHBondContact O-N 2.82Å
115T98.1Very high96.7Very high35 Ų3535.8 Ų35.822%0.21522%0.223CC..Hα-helixtrans-65.1-43.4175.2-52.40000111.6C111 S112 F113 A117 L118 L119 L184C111-T115 HydrophobicContact CB-CG2 3.97Å; S112-T115 WeakPolarHBondContact O-CB 3.43Å; S112-T115 PolarHBondContact O-N 2.88Å; S112-T115 WeakPolarHBondContact OG-CB 3.44Å; S112-T115 PolarHBondContact OG-N 2.78Å; S112-T115 VanDerWaalsContact OG-N 3.14Å; S112-T115 PolarHBondContact OG-OG1 2.82Å; F113-T115 VanDerWaalsContact C-N 3.3Å; F113-T115 PolarHBondContact O-N 2.86Å; T115-A117 VanDerWaalsContact C-N 3.32Å; T115-A117 PolarHBondContact O-N 2.78Å; T115-L118 PolarHBondContact O-N 2.91Å; T115-L119 HydrophobicContact CG2-CD1 3.81Å; T115-L119 HydrophobicContact CG2-CG 4.11Å; T115-L119 WeakPolarHBondContact O-CB 3.37Å; T115-L119 WeakPolarHBondContact O-CG 3.46Å; T115-L119 PolarHBondContact O-N 3.15Å; T115-L184 HydrophobicContact CG2-CD1 4.37Å; T115-L184 HydrophobicContact CG2-CD2 4.02Å
116L98.4Very high96.7Very high25 Ų2533.5 Ų33.513%0.13121%0.209CC..Hα-helixtrans-61.4-41.9176.6-73171.6000111.3I104 C111 S112 F113 G120 A147 L154I104-L116 HydrophobicContact CG2-CD2 3.46Å; I104-L116 VanDerWaalsContact CG2-CD2 3.46Å; C111-L116 HydrophobicContact CB-CD2 3.61Å; C111-L116 HydrophobicContact CB-CG 3.64Å; S112-L116 WeakPolarHBondContact O-CG 3.32Å; S112-L116 PolarHBondContact O-N 3.33Å; F113-L116 WeakPolarHBondContact O-CB 3.46Å; F113-L116 PolarHBondContact O-N 2.78Å; F113-L116 VanDerWaalsContact O-N 3.17Å; L116-G120 WeakPolarHBondContact O-CA 3.17Å; L116-G120 PolarHBondContact O-N 2.85Å; L116-A147 HydrophobicContact CD1-CB 3.89Å; L116-A147 HydrophobicContact CD2-CB 4.03Å; L116-L154 HydrophobicContact CB-CD1 3.81Å; L116-L154 HydrophobicContact CB-CD2 4.2Å; L116-L154 HydrophobicContact CD1-CD2 4.48Å
117A98.5Very high96.8Very high2 Ų231.1 Ų31.12%0.01719%0.186CC..Hα-helixtrans-62.5-45.5177.600000111.6F113 A114 T115 G120 S121 L154 K157 L161F113-A117 PolarHBondContact O-N 2.84Å; A114-A117 PolarHBondContact O-N 2.56Å; T115-A117 VanDerWaalsContact C-N 3.32Å; T115-A117 PolarHBondContact O-N 2.78Å; A117-G120 PolarHBondContact O-N 2.8Å; A117-S121 PolarHBondContact O-N 3.32Å; A117-S121 PolarHBondContact O-OG 3.29Å; A117-L154 HydrophobicContact CB-CD1 3.93Å; A117-K157 HydrophobicContact CB-CB 4.1Å; A117-K157 HydrophobicContact CB-CG 3.71Å; A117-L161 HydrophobicContact CB-CD1 4.16Å
118L98.7Very high96.8Very high50 Ų5032 Ų3226%0.26218%0.18SC..Hα-helixtrans-67.6-47.6179.4-177.664.6000113.1A114 T115 G120 S121 Y122A114-L118 WeakPolarHBondContact O-CB 3.29Å; A114-L118 PolarHBondContact O-N 2.82Å; T115-L118 PolarHBondContact O-N 2.91Å; L118-G120 VanDerWaalsContact C-N 3.28Å; L118-G120 PolarHBondContact O-N 3.08Å; L118-S121 PolarHBondContact O-N 3.13Å; L118-S121 PolarHBondContact O-OG 2.87Å; L118-Y122 HydrophobicContact CD1-CD2 4.4Å; L118-Y122 HydrophobicContact CD1-CE2 3.65Å; L118-Y122 HydrophobicContact CD2-CE2 4.37Å; L118-Y122 HydrophobicContact CG-CD2 4.28Å; L118-Y122 HydrophobicContact CG-CE2 3.73Å; L118-Y122 VanDerWaalsContact O-CD2 3.24Å; L118-Y122 WeakPolarHBondContact O-CD2 3.15Å; L118-Y122 PolarHBondContact O-N 3.47Å
119L98.6Very high96.8Very high4 Ų428 Ų282%0.02117%0.17CC..Hα-helixtrans-69-32.3177.7-66.4-174.8000111.5I104 T115 T123 F177 N180 L184I104-L119 HydrophobicContact CD1-CD1 3.8Å; T115-L119 HydrophobicContact CG2-CD1 3.81Å; T115-L119 HydrophobicContact CG2-CG 4.11Å; T115-L119 WeakPolarHBondContact O-CB 3.37Å; T115-L119 WeakPolarHBondContact O-CG 3.46Å; T115-L119 PolarHBondContact O-N 3.15Å; L119-T123 WeakPolarHBondContact O-CB 3.29Å; L119-T123 PolarHBondContact O-N 2.99Å; L119-T123 PolarHBondContact O-OG1 3.49Å; L119-F177 HydrophobicContact CB-CD2 3.94Å; L119-F177 HydrophobicContact CB-CE2 3.69Å; L119-F177 HydrophobicContact CD1-CE2 4.43Å; L119-F177 HydrophobicContact CD2-CD2 3.83Å; L119-F177 HydrophobicContact CD2-CE2 4.11Å; L119-F177 HydrophobicContact CD2-CG 4.12Å; L119-F177 WeakPolarHBondContact CD2-O 3.38Å; L119-F177 HydrophobicContact CG-CD2 4.41Å; L119-F177 HydrophobicContact CG-CE2 4.28Å; L119-F177 WeakPolarHBondContact O-CD2 3.39Å; L119-N180 HydrophobicContact CD2-CB 3.88Å; L119-L184 HydrophobicContact CD1-CD1 4.27Å
120G98.2Very high96.8Very high3 Ų331.4 Ų31.43%0.03119%0.188CC..Hα-helixtrans-63.2-47172.500000111.8L116 A117 L118 Y122 T123 I124L116-G120 WeakPolarHBondContact O-CA 3.17Å; L116-G120 PolarHBondContact O-N 2.85Å; A117-G120 PolarHBondContact O-N 2.8Å; L118-G120 VanDerWaalsContact C-N 3.28Å; L118-G120 PolarHBondContact O-N 3.08Å; G120-Y122 PolarHBondContact O-N 2.9Å; G120-T123 WeakPolarHBondContact O-CA 3.37Å; G120-T123 VanDerWaalsContact O-CB 3.27Å; G120-T123 WeakPolarHBondContact O-CB 3.45Å; G120-T123 PolarHBondContact O-N 3.26Å; G120-I124 WeakPolarHBondContact O-CG1 3.48Å; G120-I124 PolarHBondContact O-N 3.24Å
121S98.5Very high96.8Very high0 Ų030.8 Ų30.80%018%0.176CC..Hα-helixtrans-65-38.5179.160.20000112.8A117 L118 T123 I124 Q125 L161 Y165A117-S121 PolarHBondContact O-N 3.32Å; A117-S121 PolarHBondContact O-OG 3.29Å; L118-S121 PolarHBondContact O-N 3.13Å; L118-S121 PolarHBondContact O-OG 2.87Å; S121-T123 VanDerWaalsContact C-N 3.31Å; S121-T123 PolarHBondContact O-N 3.49Å; S121-I124 PolarHBondContact O-N 2.91Å; S121-Q125 WeakPolarHBondContact O-CB 3.32Å; S121-Q125 PolarHBondContact O-N 3.32Å; S121-L161 VanDerWaalsContact CB-CB 3.46Å; S121-Y165 PolarHBondContact OG-OH 3.08Å
122Y98.6Very high96.6Very high24 Ų2431.9 Ų31.99%0.09418%0.18CC..Hα-helixtrans-66.1-33.3170.9-65.8-43.4000113L118 G120 S126 Y165 M168 E176 F177L118-Y122 HydrophobicContact CD1-CD2 4.4Å; L118-Y122 HydrophobicContact CD1-CE2 3.65Å; L118-Y122 HydrophobicContact CD2-CE2 4.37Å; L118-Y122 HydrophobicContact CG-CD2 4.28Å; L118-Y122 HydrophobicContact CG-CE2 3.73Å; L118-Y122 VanDerWaalsContact O-CD2 3.24Å; L118-Y122 WeakPolarHBondContact O-CD2 3.15Å; L118-Y122 PolarHBondContact O-N 3.47Å; G120-Y122 PolarHBondContact O-N 2.9Å; Y122-S126 WeakPolarHBondContact O-CB 3.5Å; Y122-S126 PolarHBondContact O-N 2.69Å; Y122-Y165 HydrophobicContact CD1-CE2 4.04Å; Y122-Y165 AromaticContact CD1-CZ 3.82Å; Y122-Y165 WeakPolarHBondContact CD1-OH 3.46Å; Y122-Y165 AromaticContact CE1-CE1 3.97Å; Y122-Y165 HydrophobicContact CE1-CE1 3.97Å; Y122-Y165 HydrophobicContact CE1-CE2 4.22Å; Y122-Y165 AromaticContact CE1-CZ 3.57Å; Y122-Y165 VanDerWaalsContact CE1-OH 3.22Å; Y122-Y165 WeakPolarHBondContact CE1-OH 3.11Å; Y122-M168 HydrophobicContact CD1-SD 4.04Å; Y122-M168 HydrophobicContact CE1-CE 4.07Å; Y122-M168 HydrophobicContact CE1-SD 3.99Å; Y122-E176 HydrophobicContact CD1-CB 4.1Å; Y122-E176 HydrophobicContact CD2-CB 4.17Å; Y122-E176 HydrophobicContact CE1-CB 3.74Å; Y122-E176 HydrophobicContact CE1-CG 4.36Å; Y122-E176 HydrophobicContact CE2-CB 3.78Å; Y122-E176 HydrophobicContact CG-CB 4.32Å; Y122-F177 HydrophobicContact CD2-CB 4.33Å; Y122-F177 HydrophobicContact CG-CB 4.47Å
123T97.7Very high96.4Very high8 Ų833.2 Ų33.25%0.04919%0.187CC..Hα-helixtrans-62.6-45.5173-64.90000110.8R101 L119 G120 S121 S126 E127 L146R101-T123 PolarHBondContact NE-OG1 2.94Å; L119-T123 WeakPolarHBondContact O-CB 3.29Å; L119-T123 PolarHBondContact O-N 2.99Å; L119-T123 PolarHBondContact O-OG1 3.49Å; G120-T123 WeakPolarHBondContact O-CA 3.37Å; G120-T123 VanDerWaalsContact O-CB 3.27Å; G120-T123 WeakPolarHBondContact O-CB 3.45Å; G120-T123 PolarHBondContact O-N 3.26Å; S121-T123 VanDerWaalsContact C-N 3.31Å; S121-T123 PolarHBondContact O-N 3.49Å; T123-S126 PolarHBondContact O-N 2.95Å; T123-E127 VanDerWaalsContact O-CG 3.3Å; T123-E127 WeakPolarHBondContact O-CG 3.11Å; T123-E127 PolarHBondContact O-N 2.93Å; T123-L146 HydrophobicContact CG2-CD2 3.81Å
124I96.9Very high96.2Very high0 Ų037.4 Ų37.40%021%0.208CC..Hα-helixtrans-65.2-47.5178-62-57.1000111.3G120 S121 S126 E127 L128 Y140 V141 F144 V158 H162G120-I124 WeakPolarHBondContact O-CG1 3.48Å; G120-I124 PolarHBondContact O-N 3.24Å; S121-I124 PolarHBondContact O-N 2.91Å; I124-S126 VanDerWaalsContact C-N 3.27Å; I124-S126 PolarHBondContact O-N 3.05Å; I124-E127 PolarHBondContact O-N 3.38Å; I124-E127 VanDerWaalsContact O-N 3.16Å; I124-L128 HydrophobicContact CG2-CD1 3.9Å; I124-L128 HydrophobicContact CG2-CG 4.41Å; I124-L128 WeakPolarHBondContact O-CB 3.46Å; I124-L128 PolarHBondContact O-N 3.45Å; I124-Y140 HydrophobicContact CG2-CD2 4.44Å; I124-Y140 HydrophobicContact CG2-CE2 3.72Å; I124-V141 HydrophobicContact CD1-CB 4.49Å; I124-V141 HydrophobicContact CD1-CG1 4.18Å; I124-V141 HydrophobicContact CD1-CG2 4.1Å; I124-V141 HydrophobicContact CG1-CG1 4.37Å; I124-V141 HydrophobicContact CG1-CG2 4.02Å; I124-V141 HydrophobicContact CG2-CG2 4.49Å; I124-F144 HydrophobicContact CD1-CB 3.93Å; I124-F144 HydrophobicContact CD1-CD1 3.89Å; I124-F144 HydrophobicContact CD1-CD2 3.34Å; I124-F144 HydrophobicContact CD1-CE1 4.22Å; I124-F144 HydrophobicContact CD1-CE2 3.72Å; I124-F144 HydrophobicContact CD1-CG 3.43Å; I124-F144 VanDerWaalsContact CD1-CG 3.43Å; I124-F144 HydrophobicContact CD1-CZ 4.14Å; I124-V158 HydrophobicContact CG1-CG1 3.69Å; I124-H162 HydrophobicContact CG2-CB 4.39Å; I124-H162 WeakPolarHBondContact CG2-ND1 3.36Å
125Q97.1Very high95.8Very high0 Ų040.6 Ų40.60%022%0.215CC..Hα-helixtrans-59.2-39.5176.3-174.969.831.500112S121 G129 D130 H162 Y165 M168 A173S121-Q125 WeakPolarHBondContact O-CB 3.32Å; S121-Q125 PolarHBondContact O-N 3.32Å; Q125-G129 PolarHBondContact NE2-O 3.09Å; Q125-G129 VanDerWaalsContact O-CA 3.3Å; Q125-G129 WeakPolarHBondContact O-CA 3.47Å; Q125-G129 PolarHBondContact O-N 3.4Å; Q125-G129 PolarHBondContact OE1-O 3.39Å; Q125-D130 PolarHBondContact NE2-OD1 2.82Å; Q125-H162 PolarHBondContact OE1-CD2 2.93Å; Q125-H162 PolarHBondContact OE1-NE2 3.15Å; Q125-Y165 HydrophobicContact CB-CD2 4.01Å; Q125-Y165 HydrophobicContact CB-CE2 4.3Å; Q125-Y165 HydrophobicContact CG-CD2 4.1Å; Q125-M168 HydrophobicContact CG-CB 4.19Å; Q125-M168 HydrophobicContact CG-CG 4.11Å; Q125-M168 HydrophobicContact CG-SD 4.03Å; Q125-M168 PolarHBondContact NE2-O 2.83Å; Q125-A173 HydrophobicContact CB-CB 3.89Å; Q125-A173 HydrophobicContact CG-CB 3.76Å
126S95.8Very high95.6Very high0 Ų040 Ų400%021%0.209CC..Hα-helixtrans-64.1-42.8176.71700000111.7R101 Y122 T123 I124 P170 D174 R324R101-S126 PolarHBondContact NH2-OG 3.21Å; Y122-S126 WeakPolarHBondContact O-CB 3.5Å; Y122-S126 PolarHBondContact O-N 2.69Å; T123-S126 PolarHBondContact O-N 2.95Å; I124-S126 VanDerWaalsContact C-N 3.27Å; I124-S126 PolarHBondContact O-N 3.05Å; S126-P170 WeakPolarHBondContact O-CB 3.32Å; S126-D174 WeakPolarHBondContact CB-OD1 3.34Å; S126-D174 PolarHBondContact OG-OD1 2.99Å; S126-R324 WeakPolarHBondContact O-CD 3.31Å; S126-R324 PolarHBondContact OG-NH1 3.34Å
127E94.1Very high95.1Very high18 Ų1841.2 Ų41.28%0.08423%0.228CC..Hα-helixtrans-85.3-33.9-175.4-65.1-62.9158.600114Y94 R101 T123 I124 F144 R324 T325 A326Y94-E127 VanDerWaalsContact CE2-OE1 3.26Å; Y94-E127 WeakPolarHBondContact CE2-OE1 3.09Å; Y94-E127 PolarHBondContact OH-OE1 3.22Å; Y94-E127 PolarHBondContact OH-OE2 3.43Å; R101-E127 IonicContact CZ-OE1 3.77Å; R101-E127 IonicContact NH1-OE1 2.56Å; R101-E127 PolarHBondContact NH1-OE1 3.14Å; R101-E127 IonicContact NH2-OE1 2.82Å; T123-E127 VanDerWaalsContact O-CG 3.3Å; T123-E127 WeakPolarHBondContact O-CG 3.11Å; T123-E127 PolarHBondContact O-N 2.93Å; I124-E127 PolarHBondContact O-N 3.38Å; I124-E127 VanDerWaalsContact O-N 3.16Å; E127-F144 HydrophobicContact CB-CE1 3.75Å; E127-F144 HydrophobicContact CB-CZ 4.21Å; E127-F144 HydrophobicContact CG-CE1 3.94Å; E127-R324 WeakPolarHBondContact OE2-CB 3.39Å; E127-T325 PolarHBondContact OE2-N 3.5Å; E127-A326 PolarHBondContact OE2-N 3.37Å
128L93.3Very high94.5Very high61 Ų6149 Ų4932%0.31927%0.266SS..Hα-helixtrans-108.8-17.6-172.9-58.7-175.1000114.1I124 Y140 F144I124-L128 HydrophobicContact CG2-CD1 3.9Å; I124-L128 HydrophobicContact CG2-CG 4.41Å; I124-L128 WeakPolarHBondContact O-CB 3.46Å; I124-L128 PolarHBondContact O-N 3.45Å; L128-Y140 HydrophobicContact CD1-CD2 3.66Å; L128-Y140 HydrophobicContact CD1-CE2 4.07Å; L128-F144 HydrophobicContact CD1-CE2 4.07Å; L128-F144 HydrophobicContact CD1-CZ 4.14Å; L128-F144 HydrophobicContact CD2-CE2 4.49Å; L128-F144 HydrophobicContact CD2-CZ 3.9Å; L128-F144 HydrophobicContact CG-CE2 4.42Å; L128-F144 HydrophobicContact CG-CZ 3.98Å
129G92.9Very high94.1Very high16 Ų1651.4 Ų51.417%0.16528%0.279CS..  trans78.7-155.5-169.900000112.1Q125 H162Q125-G129 PolarHBondContact NE2-O 3.09Å; Q125-G129 VanDerWaalsContact O-CA 3.3Å; Q125-G129 WeakPolarHBondContact O-CA 3.47Å; Q125-G129 PolarHBondContact O-N 3.4Å; Q125-G129 PolarHBondContact OE1-O 3.39Å; G129-H162 PolarHBondContact O-NE2 3.4Å
130D94.3Very high93.9Very high75 Ų7552.5 Ų52.540%0.40128%0.283SS..SBendtrans-66148.2-178.2-76.4-19.8000112.2Q125 D132 S167 M168Q125-D130 PolarHBondContact NE2-OD1 2.82Å; D130-D132 PolarHBondContact O-N 3.14Å; D130-D132 VanDerWaalsContact O-N 3.13Å; D130-S167 PolarHBondContact OD1-N 3.26Å; D130-S167 WeakPolarHBondContact OD2-CA 3.41Å; D130-S167 PolarHBondContact OD2-N 3.09Å; D130-M168 PolarHBondContact OD1-N 3.33Å
131Y95.1Very high93.7Very high68 Ų6852.3 Ų52.327%0.26728%0.282SS..  trans-63115.7174.5174.3-95.6000112.1P133 H136 Y140 K163Y131-P133 HydrophobicContact CE1-CB 3.92Å; Y131-P133 HydrophobicContact CE1-CG 4.47Å; Y131-H136 HydrophobicContact CD2-CB 3.85Å; Y131-H136 AromaticContact CD2-ND1 3.77Å; Y131-H136 HydrophobicContact CE2-CB 3.58Å; Y131-Y140 HydrophobicContact CD2-CE1 4.43Å; Y131-Y140 HydrophobicContact CE2-CE1 4.19Å; Y131-K163 HydrophobicContact CD1-CB 4.49Å; Y131-K163 HydrophobicContact CD1-CG 3.8Å; Y131-K163 HydrophobicContact CD2-CG 3.72Å; Y131-K163 HydrophobicContact CE1-CD 4.44Å; Y131-K163 HydrophobicContact CE1-CG 3.96Å; Y131-K163 HydrophobicContact CE2-CD 4.29Å; Y131-K163 VanDerWaalsContact CE2-CE 3.49Å; Y131-K163 HydrophobicContact CE2-CG 3.86Å; Y131-K163 HydrophobicContact CG-CB 4.46Å; Y131-K163 HydrophobicContact CG-CG 3.67Å
132D93.3Very high93.4Very high56 Ų5655 Ų5530%0.29930%0.3SS..  trans-105.6119.5167.4-172.8-25.7000111.5D130 E134 L135 H136D130-D132 PolarHBondContact O-N 3.14Å; D130-D132 VanDerWaalsContact O-N 3.13Å; D132-E134 VanDerWaalsContact C-N 3.27Å; D132-E134 PolarHBondContact O-N 2.98Å; D132-E134 WeakPolarHBondContact OD1-CB 3.38Å; D132-E134 PolarHBondContact OD1-N 3.23Å; D132-L135 HydrophobicContact CB-CB 4.14Å; D132-L135 HydrophobicContact CB-CD1 4.12Å; D132-L135 HydrophobicContact CB-CG 4.2Å; D132-L135 PolarHBondContact O-N 2.6Å; D132-H136 PolarHBondContact N-CE1 2.73Å; D132-H136 PolarHBondContact N-ND1 3.07Å; D132-H136 VanDerWaalsContact O-CB 3.23Å; D132-H136 WeakPolarHBondContact O-CB 3.32Å; D132-H136 PolarHBondContact O-N 2.9Å; D132-H136 PolarHBondContact O-ND1 2.97Å
133P92.1Very high92.9Very high93 Ų9357 Ų5760%0.60431%0.312SS*.THydrogen-bonded Turntrans-67.7-19178.429.1-35.5000114.7Y131Y131-P133 HydrophobicContact CE1-CB 3.92Å; Y131-P133 HydrophobicContact CE1-CG 4.47Å
134E92.4Very high92.6Very high180 Ų18057.5 Ų57.584%0.84131%0.314SS*.THydrogen-bonded Turntrans-80.4-32.3176.7-60.9-171.3174.600111.6D132D132-E134 VanDerWaalsContact C-N 3.27Å; D132-E134 PolarHBondContact O-N 2.98Å; D132-E134 WeakPolarHBondContact OD1-CB 3.38Å; D132-E134 PolarHBondContact OD1-N 3.23Å
135L89.6Confident92.4Very high135 Ų13565.7 Ų65.771%0.70735%0.349SS*.THydrogen-bonded Turntrans-92.9-35.1-179.7-59.9176.8000112.8D132 G137D132-L135 HydrophobicContact CB-CB 4.14Å; D132-L135 HydrophobicContact CB-CD1 4.12Å; D132-L135 HydrophobicContact CB-CG 4.2Å; D132-L135 PolarHBondContact O-N 2.6Å; L135-G137 PolarHBondContact O-N 3.37Å
136H92.7Very high92.3Very high21 Ų2166.4 Ų66.410%0.09735%0.353CS..  trans-97.499-174.1-58.3114.6000111.5Y131 D132 Y140Y131-H136 HydrophobicContact CD2-CB 3.85Å; Y131-H136 AromaticContact CD2-ND1 3.77Å; Y131-H136 HydrophobicContact CE2-CB 3.58Å; D132-H136 PolarHBondContact N-CE1 2.73Å; D132-H136 PolarHBondContact N-ND1 3.07Å; D132-H136 VanDerWaalsContact O-CB 3.23Å; D132-H136 WeakPolarHBondContact O-CB 3.32Å; D132-H136 PolarHBondContact O-N 2.9Å; D132-H136 PolarHBondContact O-ND1 2.97Å; H136-Y140 HydrophobicContact CB-CD1 3.78Å; H136-Y140 HydrophobicContact CB-CD2 4.14Å; H136-Y140 HydrophobicContact CB-CE1 3.94Å; H136-Y140 HydrophobicContact CB-CE2 4.3Å; H136-Y140 HydrophobicContact CB-CG 3.86Å; H136-Y140 AromaticContact CD2-CD2 3.48Å; H136-Y140 VanDerWaalsContact CD2-CD2 3.48Å; H136-Y140 WeakPolarHBondContact CD2-CD2 3.23Å; H136-Y140 AromaticContact CD2-CE2 3.84Å; H136-Y140 AromaticContact CD2-CG 3.92Å
137G88.1Confident92.3Very high51 Ų5166.8 Ų66.853%0.52636%0.356SS..  trans-65.3-168.4173.300000113.9L135 D139 Y140L135-G137 PolarHBondContact O-N 3.37Å; G137-D139 VanDerWaalsContact C-N 3.32Å; G137-D139 PolarHBondContact O-N 3.09Å; G137-Y140 WeakPolarHBondContact O-CD1 3.37Å
138M87.3Confident92.1Very high165 Ų16569.3 Ų69.381%0.81338%0.375SS*.THydrogen-bonded Turntrans-73.4-20.2-175.5-65.7-173.46900114.7M159M138-M159 VanDerWaalsContact O-CE 3.26Å; M138-M159 WeakPolarHBondContact O-CE 3.26Å
139D90.4Very high92Very high102 Ų10273.3 Ų73.355%0.54540%0.396SS..THydrogen-bonded Turntrans-129.224.1-171.3-60.8-44.7000112.8G137 V141 S142G137-D139 VanDerWaalsContact C-N 3.32Å; G137-D139 PolarHBondContact O-N 3.09Å; D139-V141 PolarHBondContact O-N 3.04Å; D139-S142 WeakPolarHBondContact O-CB 3.12Å; D139-S142 PolarHBondContact O-N 2.89Å; D139-S142 PolarHBondContact O-OG 3.02Å
140Y93.4Very high92Very high26 Ų2675 Ų7510%0.10240%0.4CS..THydrogen-bonded Turntrans-61.6-16.4-174.470.7-78.7000114.5I124 L128 Y131 H136 G137 M159 H162I124-Y140 HydrophobicContact CG2-CD2 4.44Å; I124-Y140 HydrophobicContact CG2-CE2 3.72Å; L128-Y140 HydrophobicContact CD1-CD2 3.66Å; L128-Y140 HydrophobicContact CD1-CE2 4.07Å; Y131-Y140 HydrophobicContact CD2-CE1 4.43Å; Y131-Y140 HydrophobicContact CE2-CE1 4.19Å; H136-Y140 HydrophobicContact CB-CD1 3.78Å; H136-Y140 HydrophobicContact CB-CD2 4.14Å; H136-Y140 HydrophobicContact CB-CE1 3.94Å; H136-Y140 HydrophobicContact CB-CE2 4.3Å; H136-Y140 HydrophobicContact CB-CG 3.86Å; H136-Y140 AromaticContact CD2-CD2 3.48Å; H136-Y140 VanDerWaalsContact CD2-CD2 3.48Å; H136-Y140 WeakPolarHBondContact CD2-CD2 3.23Å; H136-Y140 AromaticContact CD2-CE2 3.84Å; H136-Y140 AromaticContact CD2-CG 3.92Å; G137-Y140 WeakPolarHBondContact O-CD1 3.37Å; Y140-M159 HydrophobicContact CD1-CG 4.25Å; Y140-M159 HydrophobicContact CD1-SD 3.72Å; Y140-M159 HydrophobicContact CE1-CB 4.25Å; Y140-M159 HydrophobicContact CE1-CG 3.5Å; Y140-M159 VanDerWaalsContact CE1-CG 3.5Å; Y140-M159 HydrophobicContact CE1-SD 3.41Å; Y140-M159 WeakPolarHBondContact CE1-SD 3.4Å; Y140-H162 AromaticContact CE2-CE1 3.87Å; Y140-H162 AromaticContact CE2-ND1 3.41Å; Y140-H162 WeakPolarHBondContact CE2-ND1 3.48Å; Y140-H162 AromaticContact CZ-ND1 3.49Å; Y140-H162 PolarHBondContact OH-ND1 3.23Å
141V94.8Very high92.1Very high0 Ų074.6 Ų74.60%040%0.4CS..THydrogen-bonded Turntrans-82.3-22.3177.1174.60000112.3I124 D139 D143 F144 L146 E155 V158 M159I124-V141 HydrophobicContact CD1-CB 4.49Å; I124-V141 HydrophobicContact CD1-CG1 4.18Å; I124-V141 HydrophobicContact CD1-CG2 4.1Å; I124-V141 HydrophobicContact CG1-CG1 4.37Å; I124-V141 HydrophobicContact CG1-CG2 4.02Å; I124-V141 HydrophobicContact CG2-CG2 4.49Å; D139-V141 PolarHBondContact O-N 3.04Å; V141-D143 PolarHBondContact O-N 3.38Å; V141-D143 VanDerWaalsContact O-N 3.09Å; V141-F144 WeakPolarHBondContact O-CB 3.3Å; V141-F144 PolarHBondContact O-N 2.69Å; V141-L146 HydrophobicContact CG1-CD1 3.65Å; V141-E155 HydrophobicContact CG1-CB 4.28Å; V141-E155 HydrophobicContact CG1-CG 4.19Å; V141-V158 HydrophobicContact CG1-CB 4.28Å; V141-V158 HydrophobicContact CG1-CG1 3.84Å; V141-V158 HydrophobicContact CG2-CG1 4.09Å; V141-M159 HydrophobicContact CB-CG 4.09Å; V141-M159 HydrophobicContact CG2-CG 3.34Å; V141-M159 HydrophobicContact CG2-SD 4.23Å
142S92.1Very high92.2Very high55 Ų5578.5 Ų78.539%0.38542%0.418SS..THydrogen-bonded Turntrans-64.8-18.6-174.5-50.40000113.6D139 F144 E155D139-S142 WeakPolarHBondContact O-CB 3.12Å; D139-S142 PolarHBondContact O-N 2.89Å; D139-S142 PolarHBondContact O-OG 3.02Å; S142-F144 PolarHBondContact O-N 3.41Å; S142-E155 PolarHBondContact OG-OE2 3.47Å
143D87Confident92.4Very high66 Ų6682.1 Ų82.135%0.35343%0.434SS..THydrogen-bonded Turntrans-75.3-11.7174.1-78.5-33.6000113.7V141 S327V141-D143 PolarHBondContact O-N 3.38Å; V141-D143 VanDerWaalsContact O-N 3.09Å; D143-S327 VanDerWaalsContact O-CB 3.29Å; D143-S327 WeakPolarHBondContact O-CB 3.21Å; D143-S327 PolarHBondContact O-OG 3.14Å
144F91.9Very high92.6Very high20 Ų2077.9 Ų77.99%0.08841%0.406CS..SBendtrans-100.3132.7179.6-63-96000110.8I124 E127 L128 V141 S142 L146 Q150I124-F144 HydrophobicContact CD1-CB 3.93Å; I124-F144 HydrophobicContact CD1-CD1 3.89Å; I124-F144 HydrophobicContact CD1-CD2 3.34Å; I124-F144 HydrophobicContact CD1-CE1 4.22Å; I124-F144 HydrophobicContact CD1-CE2 3.72Å; I124-F144 HydrophobicContact CD1-CG 3.43Å; I124-F144 VanDerWaalsContact CD1-CG 3.43Å; I124-F144 HydrophobicContact CD1-CZ 4.14Å; E127-F144 HydrophobicContact CB-CE1 3.75Å; E127-F144 HydrophobicContact CB-CZ 4.21Å; E127-F144 HydrophobicContact CG-CE1 3.94Å; L128-F144 HydrophobicContact CD1-CE2 4.07Å; L128-F144 HydrophobicContact CD1-CZ 4.14Å; L128-F144 HydrophobicContact CD2-CE2 4.49Å; L128-F144 HydrophobicContact CD2-CZ 3.9Å; L128-F144 HydrophobicContact CG-CE2 4.42Å; L128-F144 HydrophobicContact CG-CZ 3.98Å; V141-F144 WeakPolarHBondContact O-CB 3.3Å; V141-F144 PolarHBondContact O-N 2.69Å; S142-F144 PolarHBondContact O-N 3.41Å; F144-L146 HydrophobicContact CB-CD2 3.86Å; F144-L146 HydrophobicContact CB-CG 4.07Å; F144-L146 PolarHBondContact O-N 3.35Å; F144-Q150 PolarHBondContact O-NE2 3.47Å; F144-Q150 PolarHBondContact O-OE1 3.08Å; F144-Q150 VanDerWaalsContact O-OE1 3.05Å
145K92.8Very high92.9Very high171 Ų17170.4 Ų70.474%0.74337%0.371SS*.  trans-88.796171.9-66.6-178-178.9177.80109.2V105V105-K145 HydrophobicContact CG2-CB 4.27Å; V105-K145 WeakPolarHBondContact CG2-O 3.11Å
146L94.7Very high93.3Very high15 Ų1569.7 Ų69.78%0.07936%0.364CS..  trans-96.4-26.5-175.7-56.8180000112.8I104 T123 V141 F144 V158I104-L146 WeakPolarHBondContact CG2-O 3.24Å; T123-L146 HydrophobicContact CG2-CD2 3.81Å; V141-L146 HydrophobicContact CG1-CD1 3.65Å; F144-L146 HydrophobicContact CB-CD2 3.86Å; F144-L146 HydrophobicContact CB-CG 4.07Å; F144-L146 PolarHBondContact O-N 3.35Å; L146-V158 HydrophobicContact CD1-CB 4.43Å; L146-V158 HydrophobicContact CD1-CG1 4Å; L146-V158 HydrophobicContact CD1-CG2 3.92Å
147A95.2Very high93.6Very high8 Ų872.1 Ų72.17%0.06637%0.374CS..SBendtrans-146.1158.3-176.500000112.3L116 N149 L154L116-A147 HydrophobicContact CD1-CB 3.89Å; L116-A147 HydrophobicContact CD2-CB 4.03Å; A147-N149 VanDerWaalsContact C-N 3.31Å; A147-N149 PolarHBondContact O-N 2.78Å; A147-L154 HydrophobicContact CB-CD2 3.77Å
148P91.8Very high94Very high72 Ų7269.7 Ų69.747%0.46835%0.349SS..THydrogen-bonded Turntrans-59.6-38.9174.9-20.428.9000113.5I104 V105I104-P148 WeakPolarHBondContact O-CD 3.35Å; I104-P148 VanDerWaalsContact O-CG 3.29Å; I104-P148 WeakPolarHBondContact O-CG 3.44Å; V105-P148 WeakPolarHBondContact O-CG 3.41Å
149N89.8Confident94.6Very high144 Ų14462.7 Ų62.777%0.7732%0.315SS*.THydrogen-bonded Turntrans-123.566.7-179.7-63-33.6000109A147 T151A147-N149 VanDerWaalsContact C-N 3.31Å; A147-N149 PolarHBondContact O-N 2.78Å; N149-T151 PolarHBondContact O-N 2.96Å
150Q93Very high94.9Very high53 Ų5363.1 Ų63.125%0.24831%0.313CS..  trans-64.8127.8-178.2-173.4160.2-43.400111F144 L154 E155F144-Q150 PolarHBondContact O-NE2 3.47Å; F144-Q150 PolarHBondContact O-OE1 3.08Å; F144-Q150 VanDerWaalsContact O-OE1 3.05Å; Q150-L154 HydrophobicContact CG-CD2 4.47Å; Q150-E155 HydrophobicContact CG-CG 4.02Å; Q150-E155 WeakPolarHBondContact CG-OE1 3.06Å; Q150-E155 PolarHBondContact NE2-OE1 3.04Å
151T96.4Very high95.1Very high66 Ų6663.7 Ų63.741%0.40532%0.318SS..  trans-113156.4179.4630000110.2N149 E153 L154 E155N149-T151 PolarHBondContact O-N 2.96Å; T151-E153 VanDerWaalsContact C-N 3.25Å; T151-E153 PolarHBondContact O-N 3.38Å; T151-L154 WeakPolarHBondContact O-CB 3.2Å; T151-L154 PolarHBondContact O-N 3.05Å; T151-L154 VanDerWaalsContact O-N 3.11Å; T151-L154 PolarHBondContact OG1-N 3.41Å; T151-E155 PolarHBondContact O-N 2.89Å; T151-E155 VanDerWaalsContact O-N 3.12Å
152K96.5Very high95.3Very high149 Ų14963.7 Ų63.765%0.64832%0.318SS*.Hα-helixtrans-58.3-38.9174-71.3-162.4170-153.80112.6L154 E155 E156K152-L154 VanDerWaalsContact C-N 3.28Å; K152-L154 PolarHBondContact O-N 2.94Å; K152-E155 WeakPolarHBondContact O-CB 3.09Å; K152-E155 PolarHBondContact O-N 2.99Å; K152-E155 VanDerWaalsContact O-N 3.11Å; K152-E156 WeakPolarHBondContact O-CG 3.29Å; K152-E156 PolarHBondContact O-N 3.27Å
153E97.6Very high95.5Very high133 Ų13366.2 Ų66.262%0.62132%0.322SS*.Hα-helixtrans-60.5-37.3176.5-168.6-179.4-174.400112.2F113 T151 K157F113-E153 HydrophobicContact CE2-CG 4.45Å; F113-E153 HydrophobicContact CZ-CG 4.05Å; T151-E153 VanDerWaalsContact C-N 3.25Å; T151-E153 PolarHBondContact O-N 3.38Å; E153-K157 PolarHBondContact O-N 3.5Å; E153-K157 VanDerWaalsContact O-N 3.1Å
154L97.8Very high96Very high3 Ų366.5 Ų66.52%0.01633%0.329CS..Hα-helixtrans-66-46.1173.117762.5000111F113 L116 A117 A147 Q150 T151 K152 E156 K157 V158F113-L154 HydrophobicContact CD2-CD1 4.42Å; F113-L154 HydrophobicContact CE2-CB 3.81Å; F113-L154 HydrophobicContact CE2-CD1 4.14Å; F113-L154 HydrophobicContact CZ-CB 4.44Å; F113-L154 HydrophobicContact CZ-CD1 4.5Å; L116-L154 HydrophobicContact CB-CD1 3.81Å; L116-L154 HydrophobicContact CB-CD2 4.2Å; L116-L154 HydrophobicContact CD1-CD2 4.48Å; A117-L154 HydrophobicContact CB-CD1 3.93Å; A147-L154 HydrophobicContact CB-CD2 3.77Å; Q150-L154 HydrophobicContact CG-CD2 4.47Å; T151-L154 WeakPolarHBondContact O-CB 3.2Å; T151-L154 PolarHBondContact O-N 3.05Å; T151-L154 VanDerWaalsContact O-N 3.11Å; T151-L154 PolarHBondContact OG1-N 3.41Å; K152-L154 VanDerWaalsContact C-N 3.28Å; K152-L154 PolarHBondContact O-N 2.94Å; L154-E156 PolarHBondContact O-N 3.24Å; L154-K157 PolarHBondContact O-N 3.11Å; L154-V158 HydrophobicContact CD1-CG2 4.21Å; L154-V158 HydrophobicContact CG-CG2 4.41Å; L154-V158 WeakPolarHBondContact O-CB 3.42Å; L154-V158 VanDerWaalsContact O-CG2 3.23Å; L154-V158 WeakPolarHBondContact O-CG2 3.22Å; L154-V158 PolarHBondContact O-N 2.75Å
155E97.9Very high96.2Very high24 Ų2467 Ų6711%0.11233%0.331CS..Hα-helixtrans-60.3-45.1179-66.1178.1-17500111.6V141 S142 Q150 T151 K152 K157 V158 M159V141-E155 HydrophobicContact CG1-CB 4.28Å; V141-E155 HydrophobicContact CG1-CG 4.19Å; S142-E155 PolarHBondContact OG-OE2 3.47Å; Q150-E155 HydrophobicContact CG-CG 4.02Å; Q150-E155 WeakPolarHBondContact CG-OE1 3.06Å; Q150-E155 PolarHBondContact NE2-OE1 3.04Å; T151-E155 PolarHBondContact O-N 2.89Å; T151-E155 VanDerWaalsContact O-N 3.12Å; K152-E155 WeakPolarHBondContact O-CB 3.09Å; K152-E155 PolarHBondContact O-N 2.99Å; K152-E155 VanDerWaalsContact O-N 3.11Å; E155-K157 VanDerWaalsContact C-N 3.34Å; E155-K157 PolarHBondContact O-N 2.93Å; E155-V158 PolarHBondContact O-N 2.9Å; E155-M159 VanDerWaalsContact O-CG 3.32Å; E155-M159 WeakPolarHBondContact O-CG 3.23Å; E155-M159 PolarHBondContact O-N 2.85Å
156E97.6Very high96Very high119 Ų11969.7 Ų69.756%0.55634%0.336SS*.Hα-helixtrans-58.1-45.2174.7-73.5171-168.600111.7K152 L154 M159 E160K152-E156 WeakPolarHBondContact O-CG 3.29Å; K152-E156 PolarHBondContact O-N 3.27Å; L154-E156 PolarHBondContact O-N 3.24Å; E156-M159 HydrophobicContact CG-CE 4.32Å; E156-M159 PolarHBondContact O-N 3.44Å; E156-E160 WeakPolarHBondContact O-CB 3.45Å; E156-E160 PolarHBondContact O-N 2.88Å
157K98.4Very high95.9Very high73 Ų7373.7 Ų73.732%0.31737%0.365SS..Hα-helixtrans-68.1-37.4179.3-166.753.4167.9178.40112.7F113 A117 E153 L154 E155 E160 L161F113-K157 HydrophobicContact CE1-CG 4.49Å; F113-K157 HydrophobicContact CZ-CB 4.38Å; A117-K157 HydrophobicContact CB-CB 4.1Å; A117-K157 HydrophobicContact CB-CG 3.71Å; E153-K157 PolarHBondContact O-N 3.5Å; E153-K157 VanDerWaalsContact O-N 3.1Å; L154-K157 PolarHBondContact O-N 3.11Å; E155-K157 VanDerWaalsContact C-N 3.34Å; E155-K157 PolarHBondContact O-N 2.93Å; K157-E160 HydrophobicContact CD-CB 4.49Å; K157-E160 WeakPolarHBondContact CD-OE2 3.45Å; K157-E160 IonicContact NZ-OE1 2.74Å; K157-E160 PolarHBondContact NZ-OE1 3.42Å; K157-E160 IonicContact NZ-OE2 2.75Å; K157-E160 PolarHBondContact NZ-OE2 2.9Å; K157-E160 PolarHBondContact O-N 2.96Å; K157-L161 WeakPolarHBondContact O-CG 3.48Å; K157-L161 PolarHBondContact O-N 2.97Å; K157-L161 VanDerWaalsContact O-N 3.07Å
158V98.5Very high96Very high0 Ų075.2 Ų75.20%037%0.371CS..Hα-helixtrans-61.3-45.5173.1168.10000110.4I124 V141 L146 L154 E155 L161 H162I124-V158 HydrophobicContact CG1-CG1 3.69Å; V141-V158 HydrophobicContact CG1-CB 4.28Å; V141-V158 HydrophobicContact CG1-CG1 3.84Å; V141-V158 HydrophobicContact CG2-CG1 4.09Å; L146-V158 HydrophobicContact CD1-CB 4.43Å; L146-V158 HydrophobicContact CD1-CG1 4Å; L146-V158 HydrophobicContact CD1-CG2 3.92Å; L154-V158 HydrophobicContact CD1-CG2 4.21Å; L154-V158 HydrophobicContact CG-CG2 4.41Å; L154-V158 WeakPolarHBondContact O-CB 3.42Å; L154-V158 VanDerWaalsContact O-CG2 3.23Å; L154-V158 WeakPolarHBondContact O-CG2 3.22Å; L154-V158 PolarHBondContact O-N 2.75Å; E155-V158 PolarHBondContact O-N 2.9Å; V158-L161 PolarHBondContact O-N 3.26Å; V158-H162 WeakPolarHBondContact O-CB 3.24Å; V158-H162 PolarHBondContact O-N 3.45Å
159M98Very high96.1Very high18 Ų1875 Ų759%0.08937%0.369CS..Hα-helixtrans-64.5-40.1177.5-72.1-170.7-72.400112.6M138 Y140 V141 E155 E156 H162 K163M138-M159 VanDerWaalsContact O-CE 3.26Å; M138-M159 WeakPolarHBondContact O-CE 3.26Å; Y140-M159 HydrophobicContact CD1-CG 4.25Å; Y140-M159 HydrophobicContact CD1-SD 3.72Å; Y140-M159 HydrophobicContact CE1-CB 4.25Å; Y140-M159 HydrophobicContact CE1-CG 3.5Å; Y140-M159 VanDerWaalsContact CE1-CG 3.5Å; Y140-M159 HydrophobicContact CE1-SD 3.41Å; Y140-M159 WeakPolarHBondContact CE1-SD 3.4Å; V141-M159 HydrophobicContact CB-CG 4.09Å; V141-M159 HydrophobicContact CG2-CG 3.34Å; V141-M159 HydrophobicContact CG2-SD 4.23Å; E155-M159 VanDerWaalsContact O-CG 3.32Å; E155-M159 WeakPolarHBondContact O-CG 3.23Å; E155-M159 PolarHBondContact O-N 2.85Å; E156-M159 HydrophobicContact CG-CE 4.32Å; E156-M159 PolarHBondContact O-N 3.44Å; M159-H162 PolarHBondContact O-N 2.89Å; M159-K163 VanDerWaalsContact O-CG 3.23Å; M159-K163 WeakPolarHBondContact O-CG 3.2Å; M159-K163 PolarHBondContact O-N 3.03Å
160E97.7Very high96.3Very high110 Ų11070.1 Ų70.151%0.51435%0.345SS..Hα-helixtrans-59.1-46.9175.3-171.6-162.3137.300111.1E156 K157 S164E156-E160 WeakPolarHBondContact O-CB 3.45Å; E156-E160 PolarHBondContact O-N 2.88Å; K157-E160 HydrophobicContact CD-CB 4.49Å; K157-E160 WeakPolarHBondContact CD-OE2 3.45Å; K157-E160 IonicContact NZ-OE1 2.74Å; K157-E160 PolarHBondContact NZ-OE1 3.42Å; K157-E160 IonicContact NZ-OE2 2.75Å; K157-E160 PolarHBondContact NZ-OE2 2.9Å; K157-E160 PolarHBondContact O-N 2.96Å; E160-S164 PolarHBondContact O-N 3.14Å
161L98.3Very high96.4Very high39 Ų3968.7 Ų68.720%0.20434%0.343CS..Hα-helixtrans-66.8-43.2177.8-71172.9000112A117 S121 K157 V158 K163 S164A117-L161 HydrophobicContact CB-CD1 4.16Å; S121-L161 VanDerWaalsContact CB-CB 3.46Å; K157-L161 WeakPolarHBondContact O-CG 3.48Å; K157-L161 PolarHBondContact O-N 2.97Å; K157-L161 VanDerWaalsContact O-N 3.07Å; V158-L161 PolarHBondContact O-N 3.26Å; L161-K163 VanDerWaalsContact C-N 3.32Å; L161-K163 PolarHBondContact O-N 3.08Å; L161-S164 WeakPolarHBondContact O-CB 3.38Å; L161-S164 PolarHBondContact O-N 3.41Å; L161-S164 PolarHBondContact O-OG 3.44Å
162H97.9Very high96.3Very high0 Ų070.3 Ų70.30%035%0.345CS..Hα-helixtrans-58-43.8177.7-178.6-139000111.9I124 Q125 G129 Y140 V158 M159 S164 Y165I124-H162 HydrophobicContact CG2-CB 4.39Å; I124-H162 WeakPolarHBondContact CG2-ND1 3.36Å; Q125-H162 PolarHBondContact OE1-CD2 2.93Å; Q125-H162 PolarHBondContact OE1-NE2 3.15Å; G129-H162 PolarHBondContact O-NE2 3.4Å; Y140-H162 AromaticContact CE2-CE1 3.87Å; Y140-H162 AromaticContact CE2-ND1 3.41Å; Y140-H162 WeakPolarHBondContact CE2-ND1 3.48Å; Y140-H162 AromaticContact CZ-ND1 3.49Å; Y140-H162 PolarHBondContact OH-ND1 3.23Å; V158-H162 WeakPolarHBondContact O-CB 3.24Å; V158-H162 PolarHBondContact O-N 3.45Å; M159-H162 PolarHBondContact O-N 2.89Å; H162-S164 PolarHBondContact O-N 3.15Å; H162-Y165 PolarHBondContact O-N 3.44Å
163K97.1Very high96.4Very high108 Ų10863.2 Ų63.247%0.4732%0.315SS..Hα-helixtrans-62.5-22.1175.3-71.3169-176.5-179.90113.9Y131 M159 L161Y131-K163 HydrophobicContact CD1-CB 4.49Å; Y131-K163 HydrophobicContact CD1-CG 3.8Å; Y131-K163 HydrophobicContact CD2-CG 3.72Å; Y131-K163 HydrophobicContact CE1-CD 4.44Å; Y131-K163 HydrophobicContact CE1-CG 3.96Å; Y131-K163 HydrophobicContact CE2-CD 4.29Å; Y131-K163 VanDerWaalsContact CE2-CE 3.49Å; Y131-K163 HydrophobicContact CE2-CG 3.86Å; Y131-K163 HydrophobicContact CG-CB 4.46Å; Y131-K163 HydrophobicContact CG-CG 3.67Å; M159-K163 VanDerWaalsContact O-CG 3.23Å; M159-K163 WeakPolarHBondContact O-CG 3.2Å; M159-K163 PolarHBondContact O-N 3.03Å; L161-K163 VanDerWaalsContact C-N 3.32Å; L161-K163 PolarHBondContact O-N 3.08Å
164S97.1Very high96.4Very high72 Ų7256.9 Ų56.950%0.50329%0.285SS..Hα-helixtrans-82.2-20.7-178.380.20000113.2E160 L161 H162E160-S164 PolarHBondContact O-N 3.14Å; L161-S164 WeakPolarHBondContact O-CB 3.38Å; L161-S164 PolarHBondContact O-N 3.41Å; L161-S164 PolarHBondContact O-OG 3.44Å; H162-S164 PolarHBondContact O-N 3.15Å
165Y96.9Very high96.3Very high29 Ų2959.4 Ų59.411%0.11430%0.298CS..  trans-72.4135178.7-57-36.8000110.4S121 Y122 Q125 H162 M168S121-Y165 PolarHBondContact OG-OH 3.08Å; Y122-Y165 HydrophobicContact CD1-CE2 4.04Å; Y122-Y165 AromaticContact CD1-CZ 3.82Å; Y122-Y165 WeakPolarHBondContact CD1-OH 3.46Å; Y122-Y165 AromaticContact CE1-CE1 3.97Å; Y122-Y165 HydrophobicContact CE1-CE1 3.97Å; Y122-Y165 HydrophobicContact CE1-CE2 4.22Å; Y122-Y165 AromaticContact CE1-CZ 3.57Å; Y122-Y165 VanDerWaalsContact CE1-OH 3.22Å; Y122-Y165 WeakPolarHBondContact CE1-OH 3.11Å; Q125-Y165 HydrophobicContact CB-CD2 4.01Å; Q125-Y165 HydrophobicContact CB-CE2 4.3Å; Q125-Y165 HydrophobicContact CG-CD2 4.1Å; H162-Y165 PolarHBondContact O-N 3.44Å; Y165-M168 HydrophobicContact CD1-CE 3.84Å; Y165-M168 HydrophobicContact CD1-SD 4.42Å; Y165-M168 HydrophobicContact CD2-SD 4.35Å; Y165-M168 HydrophobicContact CE1-CE 4.16Å; Y165-M168 HydrophobicContact CG-CE 4.18Å; Y165-M168 HydrophobicContact CG-SD 4.24Å
166R88.7Confident96.4Very high229 Ų22962 Ų6286%0.86431%0.31SS*.  trans-123.1115.3177-67-169.7-179.5158.21.3109.1M168R166-M168 PolarHBondContact O-N 3.47Å
167S91.6Very high96.4Very high98 Ų9856.3 Ų56.369%0.68528%0.284SS*.SBendtrans58.133.8175.5-480000113.1D130D130-S167 PolarHBondContact OD1-N 3.26Å; D130-S167 WeakPolarHBondContact OD2-CA 3.41Å; D130-S167 PolarHBondContact OD2-N 3.09Å
168M96.4Very high96.4Very high40 Ų4052.9 Ų52.920%0.19727%0.269CS..  trans-84.1116.2175.3-179.4179.3-69.900108.4Y122 Q125 D130 Y165 R166 Q172 A173Y122-M168 HydrophobicContact CD1-SD 4.04Å; Y122-M168 HydrophobicContact CE1-CE 4.07Å; Y122-M168 HydrophobicContact CE1-SD 3.99Å; Q125-M168 HydrophobicContact CG-CB 4.19Å; Q125-M168 HydrophobicContact CG-CG 4.11Å; Q125-M168 HydrophobicContact CG-SD 4.03Å; Q125-M168 PolarHBondContact NE2-O 2.83Å; D130-M168 PolarHBondContact OD1-N 3.33Å; Y165-M168 HydrophobicContact CD1-CE 3.84Å; Y165-M168 HydrophobicContact CD1-SD 4.42Å; Y165-M168 HydrophobicContact CD2-SD 4.35Å; Y165-M168 HydrophobicContact CE1-CE 4.16Å; Y165-M168 HydrophobicContact CG-CE 4.18Å; Y165-M168 HydrophobicContact CG-SD 4.24Å; R166-M168 PolarHBondContact O-N 3.47Å; M168-Q172 HydrophobicContact CG-CB 4.1Å; M168-A173 HydrophobicContact CG-CB 4.34Å; M168-A173 HydrophobicContact SD-CB 3.98Å
169T94.7Very high96.4Very high68 Ų6855 Ų5542%0.41728%0.279SS..  trans-69.5153.7178.763.60000111.5A171 Q172 A173T169-A171 PolarHBondContact O-N 2.78Å; T169-Q172 WeakPolarHBondContact O-CB 3.41Å; T169-Q172 PolarHBondContact O-N 2.94Å; T169-Q172 WeakPolarHBondContact OG1-CB 3.38Å; T169-Q172 VanDerWaalsContact OG1-CD 3.26Å; T169-Q172 VanDerWaalsContact OG1-CG 3.22Å; T169-Q172 WeakPolarHBondContact OG1-CG 3.46Å; T169-Q172 PolarHBondContact OG1-N 3.46Å; T169-Q172 PolarHBondContact OG1-OE1 3.45Å; T169-A173 PolarHBondContact O-N 2.87Å
170P94.8Very high96.4Very high42 Ų4255.8 Ų55.827%0.27328%0.284SS..Hα-helixtrans-54.1-36.8174-33.138.9000114.7S126 A173 D174 R324S126-P170 WeakPolarHBondContact O-CB 3.32Å; P170-A173 PolarHBondContact O-N 2.93Å; P170-D174 VanDerWaalsContact O-CG 3.31Å; P170-D174 PolarHBondContact O-N 3.19Å; P170-R324 VanDerWaalsContact CB-CZ 3.41Å; P170-R324 VanDerWaalsContact CB-NE 3.34Å
171A93.8Very high96.4Very high23 Ų2350.6 Ų50.619%0.1926%0.259CS..Hα-helixtrans-66.9-38.7176.300000112.3D90 T169 D174 L175D90-A171 HydrophobicContact CB-CB 4.43Å; T169-A171 PolarHBondContact O-N 2.78Å; A171-D174 PolarHBondContact O-N 2.89Å; A171-L175 PolarHBondContact O-N 3.08Å
172Q95.9Very high96.3Very high99 Ų9951.4 Ų51.446%0.46326%0.261SS..Hα-helixtrans-66.8-40.7172.8-74.3165.3-38.600111.6M168 T169 D174 L175 E176M168-Q172 HydrophobicContact CG-CB 4.1Å; T169-Q172 WeakPolarHBondContact O-CB 3.41Å; T169-Q172 PolarHBondContact O-N 2.94Å; T169-Q172 WeakPolarHBondContact OG1-CB 3.38Å; T169-Q172 VanDerWaalsContact OG1-CD 3.26Å; T169-Q172 VanDerWaalsContact OG1-CG 3.22Å; T169-Q172 WeakPolarHBondContact OG1-CG 3.46Å; T169-Q172 PolarHBondContact OG1-N 3.46Å; T169-Q172 PolarHBondContact OG1-OE1 3.45Å; Q172-D174 VanDerWaalsContact C-N 3.33Å; Q172-D174 PolarHBondContact O-N 3.46Å; Q172-L175 PolarHBondContact O-N 3.41Å; Q172-E176 WeakPolarHBondContact O-CG 3.48Å; Q172-E176 PolarHBondContact O-N 2.84Å
173A97.6Very high96.2Very high0 Ų058.4 Ų58.40%029%0.292CS..Hα-helixtrans-61.4-41.4175.500000111.9Q125 M168 T169 P170 E176 F177Q125-A173 HydrophobicContact CB-CB 3.89Å; Q125-A173 HydrophobicContact CG-CB 3.76Å; M168-A173 HydrophobicContact CG-CB 4.34Å; M168-A173 HydrophobicContact SD-CB 3.98Å; T169-A173 PolarHBondContact O-N 2.87Å; P170-A173 PolarHBondContact O-N 2.93Å; A173-E176 PolarHBondContact O-N 3.1Å; A173-F177 VanDerWaalsContact O-CB 3.3Å; A173-F177 WeakPolarHBondContact O-CB 3.46Å; A173-F177 PolarHBondContact O-N 2.9Å
174D97.5Very high96.2Very high1 Ų154.9 Ų54.91%0.00528%0.277CS..Hα-helixtrans-60.9-44172.6-69.6-30.9000111.8R101 S126 P170 A171 Q172 F177 L178 R324R101-D174 IonicContact NH2-OD1 2.67Å; S126-D174 WeakPolarHBondContact CB-OD1 3.34Å; S126-D174 PolarHBondContact OG-OD1 2.99Å; P170-D174 VanDerWaalsContact O-CG 3.31Å; P170-D174 PolarHBondContact O-N 3.19Å; A171-D174 PolarHBondContact O-N 2.89Å; Q172-D174 VanDerWaalsContact C-N 3.33Å; Q172-D174 PolarHBondContact O-N 3.46Å; D174-F177 WeakPolarHBondContact O-CB 3.46Å; D174-F177 PolarHBondContact O-N 3.31Å; D174-L178 WeakPolarHBondContact O-CG 3.43Å; D174-L178 PolarHBondContact O-N 2.63Å; D174-R324 IonicContact OD1-NH1 3.7Å; D174-R324 PolarHBondContact OD1-NH1 2.77Å; D174-R324 IonicContact OD2-CZ 3.1Å; D174-R324 VanDerWaalsContact OD2-CZ 3.23Å; D174-R324 IonicContact OD2-NH1 3.52Å; D174-R324 PolarHBondContact OD2-NH1 3.03Å; D174-R324 IonicContact OD2-NH2 3.08Å; D174-R324 PolarHBondContact OD2-NH2 3.17Å
175L96.8Very high95.9Very high56 Ų5655.6 Ų55.629%0.29328%0.282SS..Hα-helixtrans-62.2-47.9178.1-176.564.2000111.5A85 A171 Q172 F177 L178 E179A85-L175 HydrophobicContact CB-CD1 4.17Å; A171-L175 PolarHBondContact O-N 3.08Å; Q172-L175 PolarHBondContact O-N 3.41Å; L175-F177 VanDerWaalsContact C-N 3.34Å; L175-F177 PolarHBondContact O-N 2.94Å; L175-L178 PolarHBondContact O-N 3.11Å; L175-L178 VanDerWaalsContact O-N 3.1Å; L175-E179 WeakPolarHBondContact O-CG 3.12Å; L175-E179 PolarHBondContact O-N 3.44Å
176E98.1Very high95.9Very high77 Ų7755.8 Ų55.836%0.3629%0.285SS..Hα-helixtrans-63.7-38177.7-73.2-62.5158.600112.5Y122 Q172 A173 L178 E179 N180Y122-E176 HydrophobicContact CD1-CB 4.1Å; Y122-E176 HydrophobicContact CD2-CB 4.17Å; Y122-E176 HydrophobicContact CE1-CB 3.74Å; Y122-E176 HydrophobicContact CE1-CG 4.36Å; Y122-E176 HydrophobicContact CE2-CB 3.78Å; Y122-E176 HydrophobicContact CG-CB 4.32Å; Q172-E176 WeakPolarHBondContact O-CG 3.48Å; Q172-E176 PolarHBondContact O-N 2.84Å; A173-E176 PolarHBondContact O-N 3.1Å; E176-L178 VanDerWaalsContact C-N 3.32Å; E176-L178 PolarHBondContact O-N 3.21Å; E176-E179 PolarHBondContact O-N 3.46Å; E176-N180 PolarHBondContact O-N 3.25Å; E176-N180 VanDerWaalsContact O-N 3.17Å; E176-N180 PolarHBondContact O-ND2 2.8Å
177F98.6Very high96.3Very high1 Ų145.8 Ų45.80%0.00425%0.247CC..Hα-helixtrans-55.7-49.8170.2178-78.4000110.5C97 L100 R101 I104 L119 Y122 A173 D174 L175 N180 A181C97-F177 HydrophobicContact CB-CD1 4.23Å; C97-F177 HydrophobicContact CB-CE1 4.37Å; L100-F177 HydrophobicContact CB-CE1 3.75Å; L100-F177 HydrophobicContact CB-CZ 4.1Å; L100-F177 HydrophobicContact CD1-CE1 3.93Å; R101-F177 HydrophobicContact CG-CE2 4.15Å; R101-F177 HydrophobicContact CG-CZ 3.98Å; I104-F177 HydrophobicContact CD1-CZ 4.24Å; L119-F177 HydrophobicContact CB-CD2 3.94Å; L119-F177 HydrophobicContact CB-CE2 3.69Å; L119-F177 HydrophobicContact CD1-CE2 4.43Å; L119-F177 HydrophobicContact CD2-CD2 3.83Å; L119-F177 HydrophobicContact CD2-CE2 4.11Å; L119-F177 HydrophobicContact CD2-CG 4.12Å; L119-F177 WeakPolarHBondContact CD2-O 3.38Å; L119-F177 HydrophobicContact CG-CD2 4.41Å; L119-F177 HydrophobicContact CG-CE2 4.28Å; L119-F177 WeakPolarHBondContact O-CD2 3.39Å; Y122-F177 HydrophobicContact CD2-CB 4.33Å; Y122-F177 HydrophobicContact CG-CB 4.47Å; A173-F177 VanDerWaalsContact O-CB 3.3Å; A173-F177 WeakPolarHBondContact O-CB 3.46Å; A173-F177 PolarHBondContact O-N 2.9Å; D174-F177 WeakPolarHBondContact O-CB 3.46Å; D174-F177 PolarHBondContact O-N 3.31Å; L175-F177 VanDerWaalsContact C-N 3.34Å; L175-F177 PolarHBondContact O-N 2.94Å; F177-N180 PolarHBondContact O-N 3.39Å; F177-A181 HydrophobicContact CD1-CB 4.36Å; F177-A181 HydrophobicContact CE1-CB 4.11Å; F177-A181 VanDerWaalsContact O-CB 3.28Å; F177-A181 WeakPolarHBondContact O-CB 3.4Å; F177-A181 PolarHBondContact O-N 3.35Å
178L98.5Very high96.5Very high0 Ų041.5 Ų41.50%022%0.219CC..Hα-helixtrans-67.9-39.6-177.7-67.5171.5000112.8P84 R93 L96 L100 D174 L175 E176 N180 A181 K182P84-L178 HydrophobicContact CB-CB 3.8Å; P84-L178 HydrophobicContact CB-CD1 3.92Å; P84-L178 HydrophobicContact CB-CG 4.3Å; P84-L178 HydrophobicContact CG-CB 4.07Å; R93-L178 HydrophobicContact CB-CD1 3.74Å; R93-L178 HydrophobicContact CG-CD1 3.8Å; L96-L178 HydrophobicContact CB-CD2 4.17Å; L96-L178 HydrophobicContact CD2-CD1 4.24Å; L96-L178 HydrophobicContact CD2-CD2 3.66Å; L96-L178 HydrophobicContact CG-CD2 3.61Å; L100-L178 HydrophobicContact CD1-CD2 3.47Å; L100-L178 VanDerWaalsContact CD1-CD2 3.47Å; D174-L178 WeakPolarHBondContact O-CG 3.43Å; D174-L178 PolarHBondContact O-N 2.63Å; L175-L178 PolarHBondContact O-N 3.11Å; L175-L178 VanDerWaalsContact O-N 3.1Å; E176-L178 VanDerWaalsContact C-N 3.32Å; E176-L178 PolarHBondContact O-N 3.21Å; L178-N180 PolarHBondContact O-N 2.89Å; L178-A181 PolarHBondContact O-N 2.99Å; L178-K182 WeakPolarHBondContact O-CB 3.5Å; L178-K182 PolarHBondContact O-N 3.13Å
179E97.4Very high96.5Very high44 Ų4440.7 Ų40.721%0.20622%0.216CC..Hα-helixtrans-61.4-30.9176.3-77.5-56115.600112.7L175 E176 K182 K183L175-E179 WeakPolarHBondContact O-CG 3.12Å; L175-E179 PolarHBondContact O-N 3.44Å; E176-E179 PolarHBondContact O-N 3.46Å; E179-K182 IonicContact OE1-NZ 2.84Å; E179-K182 PolarHBondContact OE1-NZ 3.21Å; E179-K182 WeakPolarHBondContact OE2-CE 3.23Å; E179-K182 IonicContact OE2-NZ 2.72Å; E179-K182 PolarHBondContact OE2-NZ 3.44Å; E179-K183 WeakPolarHBondContact O-CE 3.2Å
180N98.3Very high96.5Very high36 Ų3639.4 Ų39.419%0.19321%0.207CC..Hα-helixtrans-86.3-41.2174.8-72.9-71.8000112L119 E176 F177 L178 K182 K183L119-N180 HydrophobicContact CD2-CB 3.88Å; E176-N180 PolarHBondContact O-N 3.25Å; E176-N180 VanDerWaalsContact O-N 3.17Å; E176-N180 PolarHBondContact O-ND2 2.8Å; F177-N180 PolarHBondContact O-N 3.39Å; L178-N180 PolarHBondContact O-N 2.89Å; N180-K182 VanDerWaalsContact C-N 3.34Å; N180-K182 PolarHBondContact O-N 3.18Å; N180-K183 WeakPolarHBondContact O-CB 3.35Å; N180-K183 PolarHBondContact O-N 2.75Å
181A98.1Very high96.5Very high0 Ų041.1 Ų41.10%021%0.213CC..Hα-helixtrans-63.7-36.3179.300000112.8L100 F177 L178 K183 L184L100-A181 HydrophobicContact CD1-CB 4.04Å; F177-A181 HydrophobicContact CD1-CB 4.36Å; F177-A181 HydrophobicContact CE1-CB 4.11Å; F177-A181 VanDerWaalsContact O-CB 3.28Å; F177-A181 WeakPolarHBondContact O-CB 3.4Å; F177-A181 PolarHBondContact O-N 3.35Å; L178-A181 PolarHBondContact O-N 2.99Å; A181-K183 PolarHBondContact O-N 3.47Å; A181-K183 VanDerWaalsContact O-N 3.13Å; A181-L184 WeakPolarHBondContact O-CB 3.39Å; A181-L184 WeakPolarHBondContact O-CG 3.36Å; A181-L184 PolarHBondContact O-N 3.46Å
182K96.7Very high96.6Very high56 Ų5640.6 Ų40.624%0.24321%0.207CC..THydrogen-bonded Turntrans-62.8-20179.879.7-173.7-171.1-171.90113.8D83 P84 L178 E179 N180 L184 Y187D83-K182 IonicContact OD1-NZ 2.68Å; D83-K182 PolarHBondContact OD1-NZ 3.38Å; P84-K182 HydrophobicContact CG-CB 4.43Å; P84-K182 HydrophobicContact CG-CD 4.39Å; L178-K182 WeakPolarHBondContact O-CB 3.5Å; L178-K182 PolarHBondContact O-N 3.13Å; E179-K182 IonicContact OE1-NZ 2.84Å; E179-K182 PolarHBondContact OE1-NZ 3.21Å; E179-K182 WeakPolarHBondContact OE2-CE 3.23Å; E179-K182 IonicContact OE2-NZ 2.72Å; E179-K182 PolarHBondContact OE2-NZ 3.44Å; N180-K182 VanDerWaalsContact C-N 3.34Å; N180-K182 PolarHBondContact O-N 3.18Å; K182-L184 VanDerWaalsContact C-N 3.32Å; K182-Y187 HydrophobicContact CB-CD1 4.43Å; K182-Y187 HydrophobicContact CB-CE1 4.25Å; K182-Y187 HydrophobicContact CB-CE2 4.42Å
183K96.2Very high96.6Very high148 Ų14843.8 Ų43.864%0.64322%0.219SC*.THydrogen-bonded Turntrans-80-13.7178.7-60.4168.8-174.7160.80112.6E179 N180 A181E179-K183 WeakPolarHBondContact O-CE 3.2Å; N180-K183 WeakPolarHBondContact O-CB 3.35Å; N180-K183 PolarHBondContact O-N 2.75Å; A181-K183 PolarHBondContact O-N 3.47Å; A181-K183 VanDerWaalsContact O-N 3.13Å
184L95.7Very high96.6Very high33 Ų3344 Ų4417%0.17322%0.221CC..SBendtrans-74.1138.7-177.9-61.3175000111.4L109 C111 T115 L119 A181 K182 M186 Y187L109-L184 HydrophobicContact CD1-CB 3.73Å; L109-L184 HydrophobicContact CD1-CD1 3.85Å; L109-L184 HydrophobicContact CD1-CG 4.46Å; L109-L184 HydrophobicContact CD2-CD1 3.91Å; L109-L184 HydrophobicContact CG-CD1 3.76Å; C111-L184 VanDerWaalsContact SG-CD1 3.56Å; T115-L184 HydrophobicContact CG2-CD1 4.37Å; T115-L184 HydrophobicContact CG2-CD2 4.02Å; L119-L184 HydrophobicContact CD1-CD1 4.27Å; A181-L184 WeakPolarHBondContact O-CB 3.39Å; A181-L184 WeakPolarHBondContact O-CG 3.36Å; A181-L184 PolarHBondContact O-N 3.46Å; K182-L184 VanDerWaalsContact C-N 3.32Å; L184-M186 PolarHBondContact O-N 2.73Å; L184-M186 VanDerWaalsContact O-N 3.09Å; L184-Y187 VanDerWaalsContact O-CB 3.22Å; L184-Y187 WeakPolarHBondContact O-CB 3.43Å; L184-Y187 PolarHBondContact O-N 2.95Å
185S92Very high96.6Very high87 Ų8747.6 Ų47.661%0.60824%0.236SC*.THydrogen-bonded Turntrans-63.7-21.2-172.6600000114.7
186M95.8Very high96.4Very high33 Ų3346.8 Ų46.816%0.16323%0.232CC..THydrogen-bonded Turntrans-105.67.3-179.8-58-57.3-64.200112.9L109 P110 L184 G188 V189 L191 Y214L109-M186 HydrophobicContact CD1-CB 3.96Å; P110-M186 HydrophobicContact CG-CG 4.43Å; L184-M186 PolarHBondContact O-N 2.73Å; L184-M186 VanDerWaalsContact O-N 3.09Å; M186-G188 PolarHBondContact O-N 3.25Å; M186-G188 VanDerWaalsContact O-N 3.15Å; M186-V189 HydrophobicContact CE-CB 4.28Å; M186-V189 HydrophobicContact CE-CG1 4.28Å; M186-V189 PolarHBondContact O-N 3.45Å; M186-L191 HydrophobicContact CE-CD1 3.69Å; M186-L191 HydrophobicContact CE-CD2 3.73Å; M186-L191 HydrophobicContact CE-CG 4.06Å; M186-Y214 HydrophobicContact SD-CE1 3.95Å
187Y97.4Very high95.7Very high19 Ų1948.2 Ų48.28%0.07524%0.242CC..THydrogen-bonded Turntrans-58.1117.4177.4173.9-97.9000111Y80 P81 L100 K182 L184 V189Y80-Y187 HydrophobicContact CD1-CE2 4.22Å; P81-Y187 WeakPolarHBondContact O-CE1 3.29Å; P81-Y187 PolarHBondContact O-OH 3.44Å; L100-Y187 HydrophobicContact CD1-CD2 4.42Å; L100-Y187 HydrophobicContact CD1-CE2 3.88Å; L100-Y187 HydrophobicContact CD2-CD2 3.72Å; L100-Y187 HydrophobicContact CD2-CE2 3.82Å; L100-Y187 HydrophobicContact CG-CE2 4.47Å; K182-Y187 HydrophobicContact CB-CD1 4.43Å; K182-Y187 HydrophobicContact CB-CE1 4.25Å; K182-Y187 HydrophobicContact CB-CE2 4.42Å; L184-Y187 VanDerWaalsContact O-CB 3.22Å; L184-Y187 WeakPolarHBondContact O-CB 3.43Å; L184-Y187 PolarHBondContact O-N 2.95Å; Y187-V189 PolarHBondContact O-N 3.09Å
188G96.2Very high95.3Very high9 Ų954.6 Ų54.69%0.09327%0.272CS..THydrogen-bonded Turntrans62.124.1177.800000115.3M186 C207M186-G188 PolarHBondContact O-N 3.25Å; M186-G188 VanDerWaalsContact O-N 3.15Å; G188-C207 WeakPolarHBondContact O-CB 3.44Å
189V96.3Very high94.9Very high23 Ų2356.2 Ų56.214%0.13929%0.288CS..  trans-91114.8179.9-1760000110.8M186 Y187 L191 C207 L212 Y214M186-V189 HydrophobicContact CE-CB 4.28Å; M186-V189 HydrophobicContact CE-CG1 4.28Å; M186-V189 PolarHBondContact O-N 3.45Å; Y187-V189 PolarHBondContact O-N 3.09Å; V189-L191 HydrophobicContact CG1-CD2 3.68Å; V189-L191 HydrophobicContact CG1-CG 4.35Å; V189-C207 HydrophobicContact CG2-CB 4.13Å; V189-L212 HydrophobicContact CG1-CD1 4.35Å; V189-L212 HydrophobicContact CG2-CD1 4.04Å; V189-Y214 HydrophobicContact CG1-CE2 4.33Å
190D95.2Very high94.8Very high40 Ų4056.5 Ų56.521%0.21429%0.293CS..EExtended strand (participates in β ladder)trans-85.8118.5171-166.7-3.2000110.3H192 G205 V206 V270D190-H192 PolarHBondContact O-CD2 3.34Å; D190-H192 IonicContact OD1-NE2 2.75Å; D190-H192 IonicContact OD2-NE2 2.77Å; D190-G205 CarbonylContact O-C 3.59Å; D190-G205 VanDerWaalsContact O-CA 3.32Å; D190-G205 WeakPolarHBondContact O-CA 3.41Å; D190-V206 PolarHBondContact N-O 2.67Å; D190-V206 PolarHBondContact O-N 3.17Å; D190-V270 HydrophobicContact CB-CG1 4.35Å
191L94.9Very high94.8Very high78 Ų7860 Ų6041%0.40831%0.311SS..EExtended strand (participates in β ladder)trans-99.1134.4-170-63.8173.6000113M186 V189 I203 L204 Y214M186-L191 HydrophobicContact CE-CD1 3.69Å; M186-L191 HydrophobicContact CE-CD2 3.73Å; M186-L191 HydrophobicContact CE-CG 4.06Å; V189-L191 HydrophobicContact CG1-CD2 3.68Å; V189-L191 HydrophobicContact CG1-CG 4.35Å; L191-I203 HydrophobicContact CB-CG2 3.91Å; L191-I203 HydrophobicContact CD2-CG2 3.66Å; L191-I203 HydrophobicContact CG-CG2 4.26Å; L191-L204 CarbonylContact C-O 3.58Å; L191-L204 WeakPolarHBondContact CA-O 2.94Å; L191-Y214 HydrophobicContact CD2-CD2 4.5Å; L191-Y214 HydrophobicContact CD2-CE2 4.32Å
192H95.6Very high94.7Very high13 Ų1360.4 Ų60.46%0.0631%0.314CS..EExtended strand (participates in β ladder)trans-131.9121-179.8-61.8-93000110.8D190 A194 L204 L267D190-H192 PolarHBondContact O-CD2 3.34Å; D190-H192 IonicContact OD1-NE2 2.75Å; D190-H192 IonicContact OD2-NE2 2.77Å; H192-A194 PolarHBondContact O-N 3.1Å; H192-L204 HydrophobicContact CB-CB 4.39Å; H192-L204 PolarHBondContact N-O 3.37Å; H192-L204 PolarHBondContact O-N 3.26Å; H192-L267 HydrophobicContact CB-CD1 4.25Å; H192-L267 VanDerWaalsContact CD2-CD1 3.47Å; H192-L267 WeakPolarHBondContact CD2-CD1 3.39Å
193K95.6Very high94.7Very high166 Ų16660.8 Ų60.872%0.72232%0.318SS*.EExtended strand (participates in β ladder)trans-64.6133.7173-62.7-174.8179.1-174.40110.4P259K193-P259 HydrophobicContact CB-CG 4.46Å; K193-P259 VanDerWaalsContact O-CD 3.24Å; K193-P259 WeakPolarHBondContact O-CD 2.99Å
194A97.3Very high94.8Very high4 Ų453.7 Ų53.73%0.03329%0.287CS..EExtended strand (participates in β ladder)trans-151175.6178.600000110.8H192 I202 L204 K257 L258H192-A194 PolarHBondContact O-N 3.1Å; A194-I202 CarbonylContact C-O 3.59Å; A194-I202 HydrophobicContact CB-CD1 4.34Å; A194-I202 HydrophobicContact CB-CG1 4.07Å; A194-I202 PolarHBondContact N-O 2.91Å; A194-I202 WeakPolarHBondContact O-CG1 3.22Å; A194-I202 PolarHBondContact O-N 3.33Å; A194-L204 HydrophobicContact CB-CD1 3.81Å; A194-L204 HydrophobicContact CB-CG 3.94Å; A194-K257 CarbonylContact C-O 3.52Å; A194-K257 WeakPolarHBondContact CA-O 3.33Å; A194-L258 HydrophobicContact CB-CD1 3.71Å; A194-L258 HydrophobicContact CB-CG 4.17Å
195K97.4Very high94.9Very high76 Ų7652.1 Ų52.133%0.3328%0.279SS..EExtended strand (participates in β ladder)trans-124.5150.1166.1-71.4171175.5-68.90108.6G199 V200 D201 F256 K257K195-G199 WeakPolarHBondContact CD-O 3.47Å; K195-G199 PolarHBondContact NZ-O 3.47Å; K195-V200 WeakPolarHBondContact CA-O 3.18Å; K195-D201 WeakPolarHBondContact CE-OD1 3.43Å; K195-D201 WeakPolarHBondContact CG-OD1 3.5Å; K195-D201 IonicContact NZ-OD1 3.79Å; K195-D201 PolarHBondContact NZ-OD1 3.06Å; K195-D201 IonicContact NZ-OD2 3.43Å; K195-D201 PolarHBondContact NZ-OD2 2.8Å; K195-F256 CarbonylContact O-C 3.56Å; K195-K257 HydrophobicContact CB-CB 4.24Å; K195-K257 PolarHBondContact N-O 2.68Å; K195-K257 PolarHBondContact O-N 2.79Å
196D92.6Very high95.2Very high40 Ų4048 Ų4821%0.21425%0.25CC..  trans-73.4-168.7168.163.814.5000111.4E198 G199 V200 I202D196-E198 VanDerWaalsContact C-N 3.28Å; D196-E198 WeakPolarHBondContact OD1-CA 3.36Å; D196-E198 PolarHBondContact OD1-N 3.08Å; D196-G199 PolarHBondContact O-N 2.89Å; D196-G199 PolarHBondContact OD1-N 3.34Å; D196-V200 PolarHBondContact N-O 3.13Å; D196-V200 VanDerWaalsContact N-O 3.1Å; D196-V200 PolarHBondContact OD1-N 3.02Å; D196-V200 WeakPolarHBondContact OD2-CB 3.1Å; D196-I202 HydrophobicContact CB-CD1 4.27Å
197L84.8Confident95.2Very high106 Ų10646.9 Ų46.956%0.55525%0.245SC*.SBendtrans-72.5-23179.1-65.5178000112.9G255 Y411L197-G255 WeakPolarHBondContact CG-O 3.31Å; L197-Y411 HydrophobicContact CD1-CE2 4.44Å
198E88.4Confident95.2Very high136 Ų13647 Ų4764%0.63625%0.249SC*.SBendtrans-87.6-9.4178.6-63.1178-174.500112.1D196 V200 Y411D196-E198 VanDerWaalsContact C-N 3.28Å; D196-E198 WeakPolarHBondContact OD1-CA 3.36Å; D196-E198 PolarHBondContact OD1-N 3.08Å; E198-V200 HydrophobicContact CB-CG2 4.38Å; E198-Y411 WeakPolarHBondContact OE1-CD1 3.5Å
199G91.8Very high95.1Very high34 Ų3448.5 Ų48.535%0.35126%0.258SS..  trans93.96.1176.800000114.4K195 D196K195-G199 WeakPolarHBondContact CD-O 3.47Å; K195-G199 PolarHBondContact NZ-O 3.47Å; D196-G199 PolarHBondContact O-N 2.89Å; D196-G199 PolarHBondContact OD1-N 3.34Å
200V94.9Very high95.1Very high50 Ų5047.4 Ų47.430%0.30325%0.251SS..  trans-70.5132.4177.7-176.40000109.4K195 D196 E198 I202 K215K195-V200 WeakPolarHBondContact CA-O 3.18Å; D196-V200 PolarHBondContact N-O 3.13Å; D196-V200 VanDerWaalsContact N-O 3.1Å; D196-V200 PolarHBondContact OD1-N 3.02Å; D196-V200 WeakPolarHBondContact OD2-CB 3.1Å; E198-V200 HydrophobicContact CB-CG2 4.38Å; V200-I202 PolarHBondContact O-N 3.23Å; V200-K215 HydrophobicContact CG1-CD 4.4Å
201D97.1Very high95.2Very high108 Ų10845.6 Ų45.658%0.57824%0.241SC*.EExtended strand (participates in β ladder)trans-69.3127.6178.7-70.2-63.4000111.4K195K195-D201 WeakPolarHBondContact CE-OD1 3.43Å; K195-D201 WeakPolarHBondContact CG-OD1 3.5Å; K195-D201 IonicContact NZ-OD1 3.79Å; K195-D201 PolarHBondContact NZ-OD1 3.06Å; K195-D201 IonicContact NZ-OD2 3.43Å; K195-D201 PolarHBondContact NZ-OD2 2.8Å
202I97.4Very high95.3Very high9 Ų942 Ų425%0.04622%0.223CC..EExtended strand (participates in β ladder)trans-137.9167.3-178.857.4164.9000109.9A194 D196 V200 L204 V213 Y214 K215 F256A194-I202 CarbonylContact C-O 3.59Å; A194-I202 HydrophobicContact CB-CD1 4.34Å; A194-I202 HydrophobicContact CB-CG1 4.07Å; A194-I202 PolarHBondContact N-O 2.91Å; A194-I202 WeakPolarHBondContact O-CG1 3.22Å; A194-I202 PolarHBondContact O-N 3.33Å; D196-I202 HydrophobicContact CB-CD1 4.27Å; V200-I202 PolarHBondContact O-N 3.23Å; I202-L204 HydrophobicContact CD1-CD2 4.17Å; I202-V213 HydrophobicContact CB-CG1 4.34Å; I202-V213 HydrophobicContact CD1-CG1 3.98Å; I202-Y214 CarbonylContact C-O 3.57Å; I202-Y214 WeakPolarHBondContact CA-O 3.39Å; I202-Y214 WeakPolarHBondContact CB-O 3.44Å; I202-K215 HydrophobicContact CG2-CB 4.5Å; I202-F256 HydrophobicContact CD1-CD1 3.54Å; I202-F256 HydrophobicContact CD1-CE1 3.86Å
203I97.1Very high95.4Very high64 Ų6441.7 Ų41.733%0.32822%0.222SC..EExtended strand (participates in β ladder)trans-121.9126172-55.3174.3000108.3L191 Y214L191-I203 HydrophobicContact CB-CG2 3.91Å; L191-I203 HydrophobicContact CD2-CG2 3.66Å; L191-I203 HydrophobicContact CG-CG2 4.26Å; I203-Y214 PolarHBondContact N-O 3.11Å; I203-Y214 PolarHBondContact O-N 3.35Å
204L97.6Very high95.4Very high0 Ų034.4 Ų34.40%019%0.19CC..EExtended strand (participates in β ladder)trans-90.3127.5171.6-61.8175.7000108.8L191 H192 A194 I202 L212 V213 F238 F256 L258 L267L191-L204 CarbonylContact C-O 3.58Å; L191-L204 WeakPolarHBondContact CA-O 2.94Å; H192-L204 HydrophobicContact CB-CB 4.39Å; H192-L204 PolarHBondContact N-O 3.37Å; H192-L204 PolarHBondContact O-N 3.26Å; A194-L204 HydrophobicContact CB-CD1 3.81Å; A194-L204 HydrophobicContact CB-CG 3.94Å; I202-L204 HydrophobicContact CD1-CD2 4.17Å; L204-L212 CarbonylContact C-O 3.52Å; L204-L212 WeakPolarHBondContact CA-O 3.3Å; L204-V213 HydrophobicContact CD2-CB 4.46Å; L204-V213 HydrophobicContact CD2-CG1 4.29Å; L204-V213 HydrophobicContact CD2-CG2 3.86Å; L204-F238 HydrophobicContact CD1-CD1 4.44Å; L204-F256 HydrophobicContact CD1-CB 3.97Å; L204-F256 HydrophobicContact CD1-CD1 4.39Å; L204-F256 HydrophobicContact CD1-CD2 4.17Å; L204-F256 HydrophobicContact CD1-CG 3.91Å; L204-F256 HydrophobicContact CD2-CD1 3.99Å; L204-F256 HydrophobicContact CD2-CD2 4.42Å; L204-F256 HydrophobicContact CD2-CE1 3.91Å; L204-F256 HydrophobicContact CD2-CE2 4.35Å; L204-F256 HydrophobicContact CD2-CG 4.22Å; L204-F256 HydrophobicContact CD2-CZ 4.08Å; L204-L258 HydrophobicContact CD1-CD1 4.25Å; L204-L267 HydrophobicContact CB-CD2 4.49Å; L204-L267 HydrophobicContact CD1-CD2 3.49Å; L204-L267 VanDerWaalsContact CD1-CD2 3.49Å
205G97.3Very high95.2Very high0 Ų038.3 Ų38.30%021%0.206CC..EExtended strand (participates in β ladder)trans-106138.2172.300000111D190 L211 L212D190-G205 CarbonylContact O-C 3.59Å; D190-G205 VanDerWaalsContact O-CA 3.32Å; D190-G205 WeakPolarHBondContact O-CA 3.41Å; G205-L211 CarbonylContact O-C 3.54Å; G205-L211 WeakPolarHBondContact O-CA 3.49Å; G205-L212 PolarHBondContact N-O 2.98Å; G205-L212 PolarHBondContact O-N 3.42Å
206V97.9Very high94.8Very high0 Ų041 Ų410%022%0.224CC..EExtended strand (participates in β ladder)trans-117.3128.1171.9-172.30000108.9D190 L211 W225 L267 V270 H274D190-V206 PolarHBondContact N-O 2.67Å; D190-V206 PolarHBondContact O-N 3.17Å; V206-L211 HydrophobicContact CG1-CD1 4.36Å; V206-L211 HydrophobicContact CG2-CD1 4.08Å; V206-L211 HydrophobicContact CG2-CG 4.37Å; V206-W225 HydrophobicContact CG1-CH2 3.79Å; V206-W225 HydrophobicContact CG1-CZ2 3.68Å; V206-L267 HydrophobicContact CG2-CD1 3.54Å; V206-V270 HydrophobicContact CB-CG1 3.95Å; V206-V270 HydrophobicContact CG1-CG1 3.95Å; V206-V270 HydrophobicContact CG2-CG1 4.19Å; V206-H274 HydrophobicContact CG1-CB 3.97Å
207C97.3Very high94.3Very high9 Ų948.5 Ų48.56%0.06126%0.255CS..EExtended strand (participates in β ladder)trans-143.3-175.9177.470.60000111.7G188 V189 S209 G210 W225G188-C207 WeakPolarHBondContact O-CB 3.44Å; V189-C207 HydrophobicContact CG2-CB 4.13Å; C207-S209 PolarHBondContact O-N 2.66Å; C207-S209 VanDerWaalsContact O-N 3.15Å; C207-S209 PolarHBondContact SG-OG 2.76Å; C207-G210 PolarHBondContact N-O 3.22Å; C207-G210 VanDerWaalsContact N-O 3.08Å; C207-G210 PolarHBondContact O-N 3.01Å; C207-W225 WeakPolarHBondContact O-CZ2 3.38Å; C207-W225 PolarHBondContact O-NE1 3Å
208S96.5Very high94.5Very high23 Ų2349.4 Ų49.416%0.16126%0.26CS..THydrogen-bonded Turntrans-58.1-27.8179.958.70000114W225 F278S208-W225 PolarHBondContact O-NE1 3.17Å; S208-W225 VanDerWaalsContact O-NE1 3.14Å; S208-F278 VanDerWaalsContact CA-CD2 3.49Å
209S95.1Very high94.8Very high40 Ų4049.8 Ų49.828%0.2826%0.255SS..THydrogen-bonded Turntrans-94.9-18.6-175.184.10000115.2C207 R222 P224 W225C207-S209 PolarHBondContact O-N 2.66Å; C207-S209 VanDerWaalsContact O-N 3.15Å; C207-S209 PolarHBondContact SG-OG 2.76Å; S209-R222 PolarHBondContact OG-NH2 3.24Å; S209-P224 WeakPolarHBondContact O-CA 3.41Å; S209-W225 PolarHBondContact O-N 2.86Å
210G96.3Very high94.8Very high0 Ų052.9 Ų52.90%026%0.263CS..EExtended strand (participates in β ladder)trans160.3-167.6-174.800000115.2C207 F223 W225C207-G210 PolarHBondContact N-O 3.22Å; C207-G210 VanDerWaalsContact N-O 3.08Å; C207-G210 PolarHBondContact O-N 3.01Å; G210-F223 CarbonylContact C-O 3.56Å; G210-F223 VanDerWaalsContact CA-O 3.23Å; G210-F223 WeakPolarHBondContact CA-O 3.48Å; G210-W225 VanDerWaalsContact N-NE1 3.18Å
211L96.9Very high94.8Very high1 Ų154.1 Ų54.11%0.00527%0.268CS..EExtended strand (participates in β ladder)trans-88144.8162.3-103.969.2000110.7G205 V206 R222 F223 W225 F238 I240 C271G205-L211 CarbonylContact O-C 3.54Å; G205-L211 WeakPolarHBondContact O-CA 3.49Å; V206-L211 HydrophobicContact CG1-CD1 4.36Å; V206-L211 HydrophobicContact CG2-CD1 4.08Å; V206-L211 HydrophobicContact CG2-CG 4.37Å; L211-R222 CarbonylContact O-C 3.58Å; L211-R222 WeakPolarHBondContact O-CA 3.48Å; L211-F223 HydrophobicContact CB-CB 4.1Å; L211-F223 HydrophobicContact CB-CD2 4.02Å; L211-F223 PolarHBondContact N-O 2.86Å; L211-F223 PolarHBondContact O-N 3.12Å; L211-W225 HydrophobicContact CD1-CH2 3.1Å; L211-W225 HydrophobicContact CD1-CZ2 4.15Å; L211-W225 HydrophobicContact CD1-CZ3 3.35Å; L211-F238 HydrophobicContact CD2-CE1 3.68Å; L211-F238 HydrophobicContact CD2-CZ 4.03Å; L211-I240 HydrophobicContact CD2-CG2 4.21Å; L211-C271 HydrophobicContact CD1-CB 4.36Å
212L97.1Very high94.7Very high4 Ų454.7 Ų54.72%0.02126%0.262CS..EExtended strand (participates in β ladder)trans-124.6144.6177.2-51.3176.6000108.2V189 L204 G205 Y214 R222V189-L212 HydrophobicContact CG1-CD1 4.35Å; V189-L212 HydrophobicContact CG2-CD1 4.04Å; L204-L212 CarbonylContact C-O 3.52Å; L204-L212 WeakPolarHBondContact CA-O 3.3Å; G205-L212 PolarHBondContact N-O 2.98Å; G205-L212 PolarHBondContact O-N 3.42Å; L212-Y214 HydrophobicContact CB-CD2 4.28Å; L212-Y214 HydrophobicContact CB-CE2 3.53Å; L212-Y214 HydrophobicContact CD1-CE2 4.15Å; L212-Y214 WeakPolarHBondContact CD1-OH 3.36Å; L212-Y214 HydrophobicContact CG-CE2 4.49Å; L212-R222 HydrophobicContact CD2-CB 4.07Å; L212-R222 HydrophobicContact CD2-CG 3.73Å
213V96.4Very high94.5Very high6 Ų654.9 Ų54.94%0.03626%0.262CS..EExtended strand (participates in β ladder)trans-118.4127.5173.4-170.50000108.2I202 L204 R219 I220 N221 F223 F256I202-V213 HydrophobicContact CB-CG1 4.34Å; I202-V213 HydrophobicContact CD1-CG1 3.98Å; L204-V213 HydrophobicContact CD2-CB 4.46Å; L204-V213 HydrophobicContact CD2-CG1 4.29Å; L204-V213 HydrophobicContact CD2-CG2 3.86Å; V213-R219 CarbonylContact O-C 3.59Å; V213-R219 WeakPolarHBondContact O-CA 3.48Å; V213-I220 HydrophobicContact CB-CG1 4.01Å; V213-I220 HydrophobicContact CG1-CD1 3.85Å; V213-I220 HydrophobicContact CG1-CG1 3.83Å; V213-I220 WeakPolarHBondContact O-CG1 3.29Å; V213-I220 PolarHBondContact O-N 3.4Å; V213-N221 HydrophobicContact CB-CB 3.96Å; V213-N221 HydrophobicContact CG2-CB 4.02Å; V213-N221 PolarHBondContact N-O 2.76Å; V213-N221 PolarHBondContact O-N 2.86Å; V213-F223 HydrophobicContact CG2-CD2 4.32Å; V213-F223 HydrophobicContact CG2-CE2 3.59Å; V213-F223 HydrophobicContact CG2-CZ 4.42Å; V213-F256 HydrophobicContact CG2-CE1 4.29Å; V213-F256 HydrophobicContact CG2-CZ 4.11Å
214Y96Very high94.4Very high12 Ų1253.4 Ų53.45%0.04726%0.257CS..EExtended strand (participates in β ladder)trans-117.8139177.9-58.9-99.6000110.6M186 V189 L191 I202 I203 L212 L218 R219M186-Y214 HydrophobicContact SD-CE1 3.95Å; V189-Y214 HydrophobicContact CG1-CE2 4.33Å; L191-Y214 HydrophobicContact CD2-CD2 4.5Å; L191-Y214 HydrophobicContact CD2-CE2 4.32Å; I202-Y214 CarbonylContact C-O 3.57Å; I202-Y214 WeakPolarHBondContact CA-O 3.39Å; I202-Y214 WeakPolarHBondContact CB-O 3.44Å; I203-Y214 PolarHBondContact N-O 3.11Å; I203-Y214 PolarHBondContact O-N 3.35Å; L212-Y214 HydrophobicContact CB-CD2 4.28Å; L212-Y214 HydrophobicContact CB-CE2 3.53Å; L212-Y214 HydrophobicContact CD1-CE2 4.15Å; L212-Y214 WeakPolarHBondContact CD1-OH 3.36Å; L212-Y214 HydrophobicContact CG-CE2 4.49Å; Y214-L218 CarbonylContact C-O 3.59Å; Y214-L218 WeakPolarHBondContact CA-O 3.34Å; Y214-R219 HydrophobicContact CD1-CB 3.84Å; Y214-R219 HydrophobicContact CE1-CB 3.71Å; Y214-R219 HydrophobicContact CE1-CG 4.25Å
215K93.8Very high94.2Very high87 Ų8753.7 Ų53.738%0.37826%0.258SS..EExtended strand (participates in β ladder)trans-130131.7168.5-178.5-179.7176.3-178.80107.2V200 I202 K217 L218 I220V200-K215 HydrophobicContact CG1-CD 4.4Å; I202-K215 HydrophobicContact CG2-CB 4.5Å; K215-K217 PolarHBondContact O-N 3.12Å; K215-K217 VanDerWaalsContact O-N 3.08Å; K215-L218 PolarHBondContact N-O 3.06Å; K215-L218 WeakPolarHBondContact O-CA 3.49Å; K215-L218 WeakPolarHBondContact O-CB 3.26Å; K215-L218 PolarHBondContact O-N 3.11Å; K215-L218 VanDerWaalsContact O-O 3.1Å; K215-I220 HydrophobicContact CB-CD1 3.93Å; K215-I220 HydrophobicContact CB-CG1 4.39Å; K215-I220 HydrophobicContact CB-CG2 3.96Å
216D89Confident93.9Very high133 Ų13357 Ų5771%0.71128%0.28SS*.THydrogen-bonded Turntrans51.337.9-178.9-54-42000113.7L218D216-L218 PolarHBondContact O-N 3.35Å; D216-L218 VanDerWaalsContact O-N 3.15Å
217K82.6Confident93.6Very high196 Ų19663 Ų6385%0.85231%0.305SS*.THydrogen-bonded Turntrans67.2-2.1-175.3-49.8174.4-178.5175.30115.4K215K215-K217 PolarHBondContact O-N 3.12Å; K215-K217 VanDerWaalsContact O-N 3.08Å
218L88.5Confident93.2Very high126 Ų12663 Ų6366%0.6631%0.305SS*.EExtended strand (participates in β ladder)trans-88.7133.8172.7-67.1167.7000110Y214 K215 D216 I220Y214-L218 CarbonylContact C-O 3.59Å; Y214-L218 WeakPolarHBondContact CA-O 3.34Å; K215-L218 PolarHBondContact N-O 3.06Å; K215-L218 WeakPolarHBondContact O-CA 3.49Å; K215-L218 WeakPolarHBondContact O-CB 3.26Å; K215-L218 PolarHBondContact O-N 3.11Å; K215-L218 VanDerWaalsContact O-O 3.1Å; D216-L218 PolarHBondContact O-N 3.35Å; D216-L218 VanDerWaalsContact O-N 3.15Å; L218-I220 PolarHBondContact O-N 3.13Å
219R93.9Very high92.8Very high143 Ų14365.3 Ų65.354%0.5432%0.315SS..EExtended strand (participates in β ladder)trans-75.4110.5174.2-175.6-177.864.6-1641109V213 Y214V213-R219 CarbonylContact O-C 3.59Å; V213-R219 WeakPolarHBondContact O-CA 3.48Å; Y214-R219 HydrophobicContact CD1-CB 3.84Å; Y214-R219 HydrophobicContact CE1-CB 3.71Å; Y214-R219 HydrophobicContact CE1-CG 4.25Å
220I93.1Very high92.6Very high99 Ų9969.7 Ų69.751%0.50833%0.329SS..EExtended strand (participates in β ladder)trans-94.6-24-178.659.1166.1000113.3V213 K215 L218V213-I220 HydrophobicContact CB-CG1 4.01Å; V213-I220 HydrophobicContact CG1-CD1 3.85Å; V213-I220 HydrophobicContact CG1-CG1 3.83Å; V213-I220 WeakPolarHBondContact O-CG1 3.29Å; V213-I220 PolarHBondContact O-N 3.4Å; K215-I220 HydrophobicContact CB-CD1 3.93Å; K215-I220 HydrophobicContact CB-CG1 4.39Å; K215-I220 HydrophobicContact CB-CG2 3.96Å; L218-I220 PolarHBondContact O-N 3.13Å
221N93Very high92.4Very high77 Ų7770.9 Ų70.941%0.41234%0.336SS..EExtended strand (participates in β ladder)trans-151.5159.5-179.4-152.2-22.9000112.3V213 F223V213-N221 HydrophobicContact CB-CB 3.96Å; V213-N221 HydrophobicContact CG2-CB 4.02Å; V213-N221 PolarHBondContact N-O 2.76Å; V213-N221 PolarHBondContact O-N 2.86Å; N221-F223 HydrophobicContact CB-CZ 4.37Å; N221-F223 WeakPolarHBondContact ND2-CZ 3.22Å
222R95Very high92.3Very high119 Ų11972.9 Ų72.945%0.44935%0.35SS..EExtended strand (participates in β ladder)trans-143.7132.2177.6176.3175.3-174.3-148.95.1110.6S209 L211 L212 P224S209-R222 PolarHBondContact OG-NH2 3.24Å; L211-R222 CarbonylContact O-C 3.58Å; L211-R222 WeakPolarHBondContact O-CA 3.48Å; L212-R222 HydrophobicContact CD2-CB 4.07Å; L212-R222 HydrophobicContact CD2-CG 3.73Å; R222-P224 HydrophobicContact CG-CG 4.36Å; R222-P224 WeakPolarHBondContact O-CD 3.41Å
223F94.7Very high92.2Very high13 Ų1374.6 Ų74.66%0.05736%0.356CS..EExtended strand (participates in β ladder)trans-11793175-53.2-62.8000109.5G210 L211 V213 N221 V228 I240 I242 I254 F256G210-F223 CarbonylContact C-O 3.56Å; G210-F223 VanDerWaalsContact CA-O 3.23Å; G210-F223 WeakPolarHBondContact CA-O 3.48Å; L211-F223 HydrophobicContact CB-CB 4.1Å; L211-F223 HydrophobicContact CB-CD2 4.02Å; L211-F223 PolarHBondContact N-O 2.86Å; L211-F223 PolarHBondContact O-N 3.12Å; V213-F223 HydrophobicContact CG2-CD2 4.32Å; V213-F223 HydrophobicContact CG2-CE2 3.59Å; V213-F223 HydrophobicContact CG2-CZ 4.42Å; N221-F223 HydrophobicContact CB-CZ 4.37Å; N221-F223 WeakPolarHBondContact ND2-CZ 3.22Å; F223-V228 HydrophobicContact CB-CG2 4.19Å; F223-I240 HydrophobicContact CB-CD1 4.13Å; F223-I240 HydrophobicContact CD1-CD1 4.02Å; F223-I240 HydrophobicContact CD2-CD1 3.38Å; F223-I240 HydrophobicContact CE1-CD1 4.26Å; F223-I240 HydrophobicContact CE2-CD1 3.67Å; F223-I240 HydrophobicContact CG-CD1 3.55Å; F223-I240 HydrophobicContact CZ-CD1 4.09Å; F223-I242 HydrophobicContact CD1-CD1 3.22Å; F223-I242 HydrophobicContact CE1-CD1 3.5Å; F223-I242 HydrophobicContact CG-CD1 4.08Å; F223-I254 HydrophobicContact CD1-CD1 4.29Å; F223-I254 HydrophobicContact CE1-CD1 3.32Å; F223-I254 HydrophobicContact CE2-CD1 4.49Å; F223-I254 HydrophobicContact CZ-CD1 3.44Å; F223-I254 VanDerWaalsContact CZ-CD1 3.44Å; F223-F256 HydrophobicContact CE2-CE2 4.47Å; F223-F256 AromaticContact CE2-CZ 3.94Å; F223-F256 HydrophobicContact CE2-CZ 3.94Å; F223-F256 HydrophobicContact CZ-CZ 4.47Å
224P94.6Very high92Very high33 Ų3381.2 Ų81.221%0.21439%0.385CS..EExtended strand (participates in β ladder)trans-62.1140.9179.4-20.832.9000111.2S209 R222 P226 K227 V228S209-P224 WeakPolarHBondContact O-CA 3.41Å; R222-P224 HydrophobicContact CG-CG 4.36Å; R222-P224 WeakPolarHBondContact O-CD 3.41Å; P224-P226 VanDerWaalsContact C-CD 3.4Å; P224-P226 VanDerWaalsContact C-N 3.3Å; P224-P226 VanDerWaalsContact O-N 3.17Å; P224-K227 PolarHBondContact O-N 3.19Å; P224-V228 PolarHBondContact O-N 2.96Å
225W94.3Very high91.9Very high7 Ų790.2 Ų90.23%0.02742%0.418CS..G310 helixtrans-50.7-41.2179.8-62.1134.9000114.7V206 C207 S208 S209 G210 L211 K227 V228 I231 C271 H274 H275 R279V206-W225 HydrophobicContact CG1-CH2 3.79Å; V206-W225 HydrophobicContact CG1-CZ2 3.68Å; C207-W225 WeakPolarHBondContact O-CZ2 3.38Å; C207-W225 PolarHBondContact O-NE1 3Å; S208-W225 PolarHBondContact O-NE1 3.17Å; S208-W225 VanDerWaalsContact O-NE1 3.14Å; S209-W225 PolarHBondContact O-N 2.86Å; G210-W225 VanDerWaalsContact N-NE1 3.18Å; L211-W225 HydrophobicContact CD1-CH2 3.1Å; L211-W225 HydrophobicContact CD1-CZ2 4.15Å; L211-W225 HydrophobicContact CD1-CZ3 3.35Å; W225-K227 PolarHBondContact O-N 3.4Å; W225-K227 VanDerWaalsContact O-N 3.15Å; W225-V228 HydrophobicContact CE3-CG2 4.34Å; W225-V228 PolarHBondContact O-N 3.24Å; W225-V228 VanDerWaalsContact O-N 3.08Å; W225-I231 HydrophobicContact CZ3-CD1 3.98Å; W225-C271 HydrophobicContact CH2-CB 4.25Å; W225-H274 HydrophobicContact CH2-CB 4.48Å; W225-H274 HydrophobicContact CZ2-CB 3.76Å; W225-H275 HydrophobicContact CD2-CB 4.31Å; W225-H275 HydrophobicContact CE3-CB 4.15Å; W225-H275 HydrophobicContact CZ3-CB 4.37Å; W225-R279 HydrophobicContact CB-CB 4.24Å; W225-R279 HydrophobicContact CB-CG 4.47Å
226P90.7Very high92Very high70 Ų7086.9 Ų86.946%0.45541%0.406SS..G310 helixtrans-60.1-25.2177.7-25.936.1000115.1P224P224-P226 VanDerWaalsContact C-CD 3.4Å; P224-P226 VanDerWaalsContact C-N 3.3Å; P224-P226 VanDerWaalsContact O-N 3.17Å
227K90.3Very high92.4Very high124 Ų12482 Ų8254%0.53938%0.382SS..G310 helixtrans-88.3-15.5178.7-63.9-165.9175.1-170.60112.9P224 W225 L229 I242 R243P224-K227 PolarHBondContact O-N 3.19Å; W225-K227 PolarHBondContact O-N 3.4Å; W225-K227 VanDerWaalsContact O-N 3.15Å; K227-L229 PolarHBondContact O-N 3.15Å; K227-I242 HydrophobicContact CB-CG2 3.99Å; K227-I242 CarbonylContact O-C 3.55Å; K227-I242 WeakPolarHBondContact O-CA 3.43Å; K227-I242 WeakPolarHBondContact O-CG2 3.47Å; K227-R243 PolarHBondContact O-N 3.04Å
228V90.3Very high93.1Very high10 Ų1072.7 Ų72.76%0.06134%0.342CS..EExtended strand (participates in β ladder)trans-84.3113.7-177.8-179.60000110F223 P224 W225 I231F223-V228 HydrophobicContact CB-CG2 4.19Å; P224-V228 PolarHBondContact O-N 2.96Å; W225-V228 HydrophobicContact CE3-CG2 4.34Å; W225-V228 PolarHBondContact O-N 3.24Å; W225-V228 VanDerWaalsContact O-N 3.08Å; V228-I231 HydrophobicContact CG1-CD1 3.96Å; V228-I231 HydrophobicContact CG1-CG1 3.57Å
229L87.8Confident93.4Very high71 Ų7169.7 Ų69.737%0.37232%0.324SS..EExtended strand (participates in β ladder)trans-82-42.3178.1-73.1176.4000112.9K227 K241 R243 E251K227-L229 PolarHBondContact O-N 3.15Å; L229-K241 HydrophobicContact CB-CB 4.42Å; L229-K241 WeakPolarHBondContact CB-O 3.5Å; L229-K241 PolarHBondContact N-O 3.44Å; L229-R243 HydrophobicContact CD1-CB 4.45Å; L229-R243 HydrophobicContact CD1-CG 3.81Å; L229-R243 HydrophobicContact CD2-CG 3.36Å; L229-R243 VanDerWaalsContact CD2-NE 3.31Å; L229-R243 HydrophobicContact CG-CB 4.38Å; L229-R243 HydrophobicContact CG-CG 3.42Å; L229-R243 VanDerWaalsContact CG-CG 3.42Å; L229-E251 HydrophobicContact CD1-CG 4.3Å; L229-E251 WeakPolarHBondContact CD1-OE1 3.26Å
230K90.3Very high93.4Very high132 Ų13262.9 Ų62.957%0.57430%0.298SS*.EExtended strand (participates in β ladder)trans-150.7139.8-173.2-171.3175.5-179.5176.60110.8I240 K241K230-I240 CarbonylContact O-C 3.53Å; K230-I240 WeakPolarHBondContact O-CA 3.5Å; K230-K241 HydrophobicContact CB-CB 3.94Å; K230-K241 PolarHBondContact N-O 3.3Å; K230-K241 PolarHBondContact O-N 2.91Å
231I92.9Very high93.4Very high26 Ų2661 Ų6113%0.13329%0.286CS..EExtended strand (participates in β ladder)trans-120.8127.4174.7-48.8-176.4000108.3W225 V228 F238 I240 W268 C271W225-I231 HydrophobicContact CZ3-CD1 3.98Å; V228-I231 HydrophobicContact CG1-CD1 3.96Å; V228-I231 HydrophobicContact CG1-CG1 3.57Å; I231-F238 HydrophobicContact CG2-CD2 4.46Å; I231-F238 HydrophobicContact CG2-CE2 3.31Å; I231-F238 HydrophobicContact CG2-CZ 3.38Å; I231-I240 HydrophobicContact CG2-CG2 4.41Å; I231-W268 PolarHBondContact O-NE1 2.82Å; I231-C271 HydrophobicContact CD1-CB 3.69Å; I231-C271 HydrophobicContact CG2-CB 4.11Å
232S93.5Very high93.2Very high43 Ų4358.4 Ų58.430%0.30127%0.272SS..EExtended strand (participates in β ladder)trans-145.7166-178.566.50000111.9F239S232-F239 PolarHBondContact N-O 2.94Å; S232-F239 PolarHBondContact O-N 3.14Å
233Y95.3Very high92.6Very high40 Ų4059.7 Ų59.716%0.15728%0.277CS..EExtended strand (participates in β ladder)trans-146.8149.8174.576.1-73.9000109.8S237 Y261 A264 K265 W268Y233-S237 CarbonylContact C-O 3.56Å; Y233-S237 WeakPolarHBondContact CA-O 3.24Å; Y233-S237 WeakPolarHBondContact CB-O 3.5Å; Y233-Y261 HydrophobicContact CD2-CE2 4.43Å; Y233-Y261 HydrophobicContact CE2-CD2 4.11Å; Y233-Y261 AromaticContact CE2-CE2 3.55Å; Y233-Y261 HydrophobicContact CE2-CE2 3.55Å; Y233-A264 HydrophobicContact CD2-CB 4.15Å; Y233-K265 HydrophobicContact CD2-CB 4.43Å; Y233-K265 HydrophobicContact CE2-CB 3.74Å; Y233-K265 HydrophobicContact CE2-CG 4.19Å; Y233-W268 HydrophobicContact CD1-CB 3.61Å; Y233-W268 AromaticContact CD1-CD1 3.71Å; Y233-W268 AromaticContact CD1-CD2 3.59Å; Y233-W268 HydrophobicContact CD1-CD2 3.59Å; Y233-W268 HydrophobicContact CD1-CE3 4.11Å; Y233-W268 AromaticContact CD1-CG 3.32Å; Y233-W268 HydrophobicContact CD1-CG 3.32Å; Y233-W268 HydrophobicContact CE1-CB 4.21Å; Y233-W268 AromaticContact CE1-CD2 3.52Å; Y233-W268 HydrophobicContact CE1-CD2 3.52Å; Y233-W268 AromaticContact CE1-CE3 3.59Å; Y233-W268 HydrophobicContact CE1-CE3 3.59Å; Y233-W268 AromaticContact CE1-CG 3.79Å; Y233-W268 HydrophobicContact CE1-CG 3.79Å; Y233-W268 HydrophobicContact CE1-CZ3 4.23Å; Y233-W268 HydrophobicContact CG-CB 4.09Å; Y233-W268 HydrophobicContact CG-CG 4.24Å
234K93.4Very high91.7Very high145 Ų14561.5 Ų61.563%0.6329%0.29SS*.EExtended strand (participates in β ladder)trans-143.8125176.3-176179.8179-177.70109S236 S237 F239K234-S236 PolarHBondContact O-N 2.8Å; K234-S237 PolarHBondContact N-O 3.18Å; K234-S237 WeakPolarHBondContact O-CB 3.4Å; K234-S237 PolarHBondContact O-N 2.84Å; K234-F239 HydrophobicContact CB-CE2 4.26Å
235R93.4Very high90.4Very high200 Ų20061.8 Ų61.876%0.75530%0.299SS*.THydrogen-bonded Turntrans52.6-123.5-171.2-60177.8177.5164.9-3.5109.1Y261R235-Y261 WeakPolarHBondContact O-CA 3.38Å; R235-Y261 WeakPolarHBondContact O-CD2 3.26Å
236S96.2Very high89.1Confident18 Ų1871.3 Ų71.313%0.12634%0.343CS..THydrogen-bonded Turntrans-96.89.9175.173.50000113.9K234 K257 L258 S260K234-S236 PolarHBondContact O-N 2.8Å; S236-K257 WeakPolarHBondContact OG-CD 3.22Å; S236-K257 WeakPolarHBondContact OG-CE 3.34Å; S236-K257 PolarHBondContact OG-NZ 3.43Å; S236-L258 VanDerWaalsContact CB-O 3.3Å; S236-L258 WeakPolarHBondContact CB-O 3.43Å; S236-L258 WeakPolarHBondContact O-CA 3.49Å; S236-L258 WeakPolarHBondContact O-CB 3.4Å; S236-L258 PolarHBondContact O-N 3.35Å; S236-L258 PolarHBondContact OG-O 3.43Å; S236-S260 VanDerWaalsContact CB-C 3.48Å
237S96.4Very high87.3Confident30 Ų3076.9 Ų76.921%0.2136%0.363CS..EExtended strand (participates in β ladder)trans-97.7140.1176.8-58.50000110.8Y233 K234 F256Y233-S237 CarbonylContact C-O 3.56Å; Y233-S237 WeakPolarHBondContact CA-O 3.24Å; Y233-S237 WeakPolarHBondContact CB-O 3.5Å; K234-S237 PolarHBondContact N-O 3.18Å; K234-S237 WeakPolarHBondContact O-CB 3.4Å; K234-S237 PolarHBondContact O-N 2.84Å; S237-F256 CarbonylContact C-O 3.49Å; S237-F256 VanDerWaalsContact CA-O 3.29Å; S237-F256 WeakPolarHBondContact CA-O 3.33Å
238F97.3Very high85.9Confident0 Ų075.7 Ų75.70%036%0.36CS..EExtended strand (participates in β ladder)trans-118.1138.9178.9173.7-98.1000108.8L204 L211 I231 I240 G255 F256 L258 L267 W268L204-F238 HydrophobicContact CD1-CD1 4.44Å; L211-F238 HydrophobicContact CD2-CE1 3.68Å; L211-F238 HydrophobicContact CD2-CZ 4.03Å; I231-F238 HydrophobicContact CG2-CD2 4.46Å; I231-F238 HydrophobicContact CG2-CE2 3.31Å; I231-F238 HydrophobicContact CG2-CZ 3.38Å; F238-I240 HydrophobicContact CE1-CG2 3.6Å; F238-I240 HydrophobicContact CZ-CG2 3.82Å; F238-G255 CarbonylContact O-C 3.45Å; F238-G255 WeakPolarHBondContact O-CA 3.45Å; F238-F256 AromaticContact CD1-CD2 3.88Å; F238-F256 HydrophobicContact CD1-CD2 3.88Å; F238-F256 HydrophobicContact CE1-CD2 4.39Å; F238-F256 PolarHBondContact N-O 2.96Å; F238-F256 PolarHBondContact O-N 3.08Å; F238-L258 HydrophobicContact CB-CD1 3.95Å; F238-L267 HydrophobicContact CB-CD2 4.31Å; F238-L267 HydrophobicContact CD1-CD2 3.69Å; F238-L267 HydrophobicContact CD2-CD2 3.96Å; F238-L267 HydrophobicContact CD2-CG 4.14Å; F238-L267 HydrophobicContact CE1-CD2 3.94Å; F238-L267 HydrophobicContact CE1-CG 4.46Å; F238-L267 HydrophobicContact CE2-CD2 4.17Å; F238-L267 HydrophobicContact CE2-CG 4.03Å; F238-L267 HydrophobicContact CG-CD2 3.72Å; F238-L267 HydrophobicContact CG-CG 4.4Å; F238-L267 HydrophobicContact CZ-CD2 4.16Å; F238-L267 HydrophobicContact CZ-CG 4.2Å; F238-W268 HydrophobicContact CD2-CB 4.25Å; F238-W268 HydrophobicContact CE2-CB 4.19Å
239F95.6Very high84.2Confident63 Ų6382.7 Ų82.728%0.27639%0.392SS..EExtended strand (participates in β ladder)trans-135.4138.2-173.9-55.4-86.1000111.3S232 K234 T253 I254S232-F239 PolarHBondContact N-O 2.94Å; S232-F239 PolarHBondContact O-N 3.14Å; K234-F239 HydrophobicContact CB-CE2 4.26Å; F239-T253 HydrophobicContact CB-CG2 4.42Å; F239-I254 CarbonylContact C-O 3.46Å; F239-I254 VanDerWaalsContact CA-O 3.27Å; F239-I254 WeakPolarHBondContact CA-O 3.39Å
240I94.3Very high82.5Confident1 Ų187.4 Ų87.41%0.00541%0.406CS..EExtended strand (participates in β ladder)trans-119.1137.3169.560.3177.6000109.5L211 F223 K230 I231 F238 I242 T253 I254 F256L211-I240 HydrophobicContact CD2-CG2 4.21Å; F223-I240 HydrophobicContact CB-CD1 4.13Å; F223-I240 HydrophobicContact CD1-CD1 4.02Å; F223-I240 HydrophobicContact CD2-CD1 3.38Å; F223-I240 HydrophobicContact CE1-CD1 4.26Å; F223-I240 HydrophobicContact CE2-CD1 3.67Å; F223-I240 HydrophobicContact CG-CD1 3.55Å; F223-I240 HydrophobicContact CZ-CD1 4.09Å; K230-I240 CarbonylContact O-C 3.53Å; K230-I240 WeakPolarHBondContact O-CA 3.5Å; I231-I240 HydrophobicContact CG2-CG2 4.41Å; F238-I240 HydrophobicContact CE1-CG2 3.6Å; F238-I240 HydrophobicContact CZ-CG2 3.82Å; I240-I242 HydrophobicContact CD1-CD1 4.06Å; I240-I242 HydrophobicContact CD1-CG1 4.38Å; I240-I242 HydrophobicContact CG1-CG1 4.42Å; I240-T253 CarbonylContact O-C 3.57Å; I240-T253 WeakPolarHBondContact O-CA 3.26Å; I240-I254 HydrophobicContact CD1-CB 4.27Å; I240-I254 HydrophobicContact CD1-CD1 4.43Å; I240-I254 HydrophobicContact CG1-CB 3.78Å; I240-I254 HydrophobicContact CG1-CG1 4.49Å; I240-I254 PolarHBondContact N-O 2.99Å; I240-I254 PolarHBondContact O-N 3.21Å; I240-F256 HydrophobicContact CD1-CE2 4.18Å; I240-F256 HydrophobicContact CG1-CE2 4.35Å
241K91.4Very high81.6Confident59 Ų5986 Ų8626%0.25740%0.401SS..EExtended strand (participates in β ladder)trans-105.8127.4170.5-164.3-177.8-168.4-159.40107.8L229 K230 E251L229-K241 HydrophobicContact CB-CB 4.42Å; L229-K241 WeakPolarHBondContact CB-O 3.5Å; L229-K241 PolarHBondContact N-O 3.44Å; K230-K241 HydrophobicContact CB-CB 3.94Å; K230-K241 PolarHBondContact N-O 3.3Å; K230-K241 PolarHBondContact O-N 2.91Å; K241-E251 VanDerWaalsContact CE-OE1 3.29Å; K241-E251 WeakPolarHBondContact CE-OE1 3.48Å; K241-E251 WeakPolarHBondContact CE-OE2 3.26Å; K241-E251 HydrophobicContact CG-CB 4.4Å; K241-E251 IonicContact NZ-OE1 2.74Å; K241-E251 PolarHBondContact NZ-OE1 2.71Å; K241-E251 IonicContact NZ-OE2 3.14Å; K241-E251 PolarHBondContact NZ-OE2 3.3Å
242I89.3Confident81Confident22 Ų2287.3 Ų87.311%0.11341%0.412CS..EExtended strand (participates in β ladder)trans-110.4146.8-175.5-52.9-176.2000108.9F223 K227 I240 S252 I254F223-I242 HydrophobicContact CD1-CD1 3.22Å; F223-I242 HydrophobicContact CE1-CD1 3.5Å; F223-I242 HydrophobicContact CG-CD1 4.08Å; K227-I242 HydrophobicContact CB-CG2 3.99Å; K227-I242 CarbonylContact O-C 3.55Å; K227-I242 WeakPolarHBondContact O-CA 3.43Å; K227-I242 WeakPolarHBondContact O-CG2 3.47Å; I240-I242 HydrophobicContact CD1-CD1 4.06Å; I240-I242 HydrophobicContact CD1-CG1 4.38Å; I240-I242 HydrophobicContact CG1-CG1 4.42Å; I242-S252 PolarHBondContact N-O 2.67Å; I242-I254 HydrophobicContact CD1-CD1 3.49Å; I242-I254 VanDerWaalsContact CD1-CD1 3.49Å; I242-I254 HydrophobicContact CD1-CG1 4.27Å
243R81.7Confident80.7Confident147 Ų14789.5 Ų89.556%0.55542%0.424SS*.PPolyproline II helixtrans-59140.3169.8-71.4-171.1-176.8-173.6-0.3110K227 L229K227-R243 PolarHBondContact O-N 3.04Å; L229-R243 HydrophobicContact CD1-CB 4.45Å; L229-R243 HydrophobicContact CD1-CG 3.81Å; L229-R243 HydrophobicContact CD2-CG 3.36Å; L229-R243 VanDerWaalsContact CD2-NE 3.31Å; L229-R243 HydrophobicContact CG-CB 4.38Å; L229-R243 HydrophobicContact CG-CG 3.42Å; L229-R243 VanDerWaalsContact CG-CG 3.42Å
244P75.9Confident80.6Confident50 Ų5089.5 Ų89.533%0.32543%0.426SS..PPolyproline II helixtrans-56.9142.2167.5-8.821.3000109.8E248 Y250 E251P244-E248 HydrophobicContact CB-CB 4.44Å; P244-E248 WeakPolarHBondContact CB-O 3.4Å; P244-Y250 WeakPolarHBondContact CB-O 3.45Å; P244-E251 HydrophobicContact CG-CG 4.02Å
245G68.6Low80.6Confident39 Ų3982.8 Ų82.840%0.40240%0.398SS..PPolyproline II helixtrans-67.6171.616800000112Q247 E248G245-Q247 PolarHBondContact O-N 2.91Å; G245-E248 PolarHBondContact O-N 2.79Å; G245-E248 VanDerWaalsContact O-N 3.14Å
246E66.1Low80.8Confident207 Ų20773.9 Ų73.997%0.96737%0.365SS*.SBendtrans-59.6-27.1178.1-73.6174.6-18000113.1
247Q52.9Low80.9Confident187 Ų18777.7 Ų77.787%0.87438%0.379SS*.SBendtrans-100-12.5177.1-66.6178.2-21.900113.9G245G245-Q247 PolarHBondContact O-N 2.91Å
248E60.5Low80.9Confident99 Ų9976.5 Ų76.546%0.46337%0.371SS..  trans-99.3125180-68.7-177.9163.100109.4P244 G245 Y250P244-E248 HydrophobicContact CB-CB 4.44Å; P244-E248 WeakPolarHBondContact CB-O 3.4Å; G245-E248 PolarHBondContact O-N 2.79Å; G245-E248 VanDerWaalsContact O-N 3.14Å; E248-Y250 VanDerWaalsContact C-N 3.33Å
249H54.8Low80.8Confident158 Ų15881.2 Ų81.273%0.73140%0.401SS*.  trans-87.61.8-179.5-65.3-55.2000114.2
250Y52.5Low80.8Confident170 Ų17080.6 Ų80.667%0.66741%0.405SS*.SBendtrans-126.2141.4-170.1-28.1-78.7000112.5P244 E248 S252P244-Y250 WeakPolarHBondContact CB-O 3.45Å; E248-Y250 VanDerWaalsContact C-N 3.33Å; Y250-S252 PolarHBondContact O-N 3.08Å
251E70.9Confident80.9Confident103 Ų10386 Ų8648%0.48143%0.426SS..  trans-75.4114.1174.3-61.9170.2110.200110.6L229 K241 P244L229-E251 HydrophobicContact CD1-CG 4.3Å; L229-E251 WeakPolarHBondContact CD1-OE1 3.26Å; K241-E251 VanDerWaalsContact CE-OE1 3.29Å; K241-E251 WeakPolarHBondContact CE-OE1 3.48Å; K241-E251 WeakPolarHBondContact CE-OE2 3.26Å; K241-E251 HydrophobicContact CG-CB 4.4Å; K241-E251 IonicContact NZ-OE1 2.74Å; K241-E251 PolarHBondContact NZ-OE1 2.71Å; K241-E251 IonicContact NZ-OE2 3.14Å; K241-E251 PolarHBondContact NZ-OE2 3.3Å; P244-E251 HydrophobicContact CG-CG 4.02Å
252S80.6Confident80.9Confident52 Ų5293.2 Ų93.236%0.36445%0.451SS..  trans-80.6125.3179.3-690000111.8I242 Y250I242-S252 PolarHBondContact N-O 2.67Å; Y250-S252 PolarHBondContact O-N 3.08Å
253T88.6Confident81.2Confident89 Ų8993.3 Ų93.355%0.54646%0.456SS..EExtended strand (participates in β ladder)trans-105.2118.7172.4-59.40000110.1F239 I240F239-T253 HydrophobicContact CB-CG2 4.42Å; I240-T253 CarbonylContact O-C 3.57Å; I240-T253 WeakPolarHBondContact O-CA 3.26Å
254I91.3Very high81.9Confident41 Ų4186.3 Ų86.321%0.2143%0.43CS..EExtended strand (participates in β ladder)trans-106.4132.9-179.1-52.4-180000109.1F223 F239 I240 I242 F256F223-I254 HydrophobicContact CD1-CD1 4.29Å; F223-I254 HydrophobicContact CE1-CD1 3.32Å; F223-I254 HydrophobicContact CE2-CD1 4.49Å; F223-I254 HydrophobicContact CZ-CD1 3.44Å; F223-I254 VanDerWaalsContact CZ-CD1 3.44Å; F239-I254 CarbonylContact C-O 3.46Å; F239-I254 VanDerWaalsContact CA-O 3.27Å; F239-I254 WeakPolarHBondContact CA-O 3.39Å; I240-I254 HydrophobicContact CD1-CB 4.27Å; I240-I254 HydrophobicContact CD1-CD1 4.43Å; I240-I254 HydrophobicContact CG1-CB 3.78Å; I240-I254 HydrophobicContact CG1-CG1 4.49Å; I240-I254 PolarHBondContact N-O 2.99Å; I240-I254 PolarHBondContact O-N 3.21Å; I242-I254 HydrophobicContact CD1-CD1 3.49Å; I242-I254 VanDerWaalsContact CD1-CD1 3.49Å; I242-I254 HydrophobicContact CD1-CG1 4.27Å; I254-F256 HydrophobicContact CB-CE2 4.47Å; I254-F256 HydrophobicContact CG2-CE1 4.22Å; I254-F256 HydrophobicContact CG2-CE2 3.71Å; I254-F256 HydrophobicContact CG2-CZ 3.53Å
255G94.3Very high82.7Confident4 Ų487.2 Ų87.24%0.04143%0.428CS..EExtended strand (participates in β ladder)trans-116.8145.8-17800000113L197 F238L197-G255 WeakPolarHBondContact CG-O 3.31Å; F238-G255 CarbonylContact O-C 3.45Å; F238-G255 WeakPolarHBondContact O-CA 3.45Å
256F97.5Very high83.9Confident12 Ų1287.8 Ų87.85%0.05342%0.42CS..EExtended strand (participates in β ladder)trans-135.2145.4177.1-56.5-78.2000110.2K195 I202 L204 V213 F223 S237 F238 I240 I254 L258K195-F256 CarbonylContact O-C 3.56Å; I202-F256 HydrophobicContact CD1-CD1 3.54Å; I202-F256 HydrophobicContact CD1-CE1 3.86Å; L204-F256 HydrophobicContact CD1-CB 3.97Å; L204-F256 HydrophobicContact CD1-CD1 4.39Å; L204-F256 HydrophobicContact CD1-CD2 4.17Å; L204-F256 HydrophobicContact CD1-CG 3.91Å; L204-F256 HydrophobicContact CD2-CD1 3.99Å; L204-F256 HydrophobicContact CD2-CD2 4.42Å; L204-F256 HydrophobicContact CD2-CE1 3.91Å; L204-F256 HydrophobicContact CD2-CE2 4.35Å; L204-F256 HydrophobicContact CD2-CG 4.22Å; L204-F256 HydrophobicContact CD2-CZ 4.08Å; V213-F256 HydrophobicContact CG2-CE1 4.29Å; V213-F256 HydrophobicContact CG2-CZ 4.11Å; F223-F256 HydrophobicContact CE2-CE2 4.47Å; F223-F256 AromaticContact CE2-CZ 3.94Å; F223-F256 HydrophobicContact CE2-CZ 3.94Å; F223-F256 HydrophobicContact CZ-CZ 4.47Å; S237-F256 CarbonylContact C-O 3.49Å; S237-F256 VanDerWaalsContact CA-O 3.29Å; S237-F256 WeakPolarHBondContact CA-O 3.33Å; F238-F256 AromaticContact CD1-CD2 3.88Å; F238-F256 HydrophobicContact CD1-CD2 3.88Å; F238-F256 HydrophobicContact CE1-CD2 4.39Å; F238-F256 PolarHBondContact N-O 2.96Å; F238-F256 PolarHBondContact O-N 3.08Å; I240-F256 HydrophobicContact CD1-CE2 4.18Å; I240-F256 HydrophobicContact CG1-CE2 4.35Å; I254-F256 HydrophobicContact CB-CE2 4.47Å; I254-F256 HydrophobicContact CG2-CE1 4.22Å; I254-F256 HydrophobicContact CG2-CE2 3.71Å; I254-F256 HydrophobicContact CG2-CZ 3.53Å; F256-L258 HydrophobicContact CB-CD1 4.12Å
257K97.9Very high85.3Confident98 Ų9877.9 Ų77.943%0.42637%0.373SS..EExtended strand (participates in β ladder)trans-104.3120.3178.7-175.365.1163.7-1770110.4A194 K195 S236A194-K257 CarbonylContact C-O 3.52Å; A194-K257 WeakPolarHBondContact CA-O 3.33Å; K195-K257 HydrophobicContact CB-CB 4.24Å; K195-K257 PolarHBondContact N-O 2.68Å; K195-K257 PolarHBondContact O-N 2.79Å; S236-K257 WeakPolarHBondContact OG-CD 3.22Å; S236-K257 WeakPolarHBondContact OG-CE 3.34Å; S236-K257 PolarHBondContact OG-NZ 3.43Å
258L97.2Very high87.4Confident6 Ų669.9 Ų69.93%0.03134%0.335CS..  trans-101159.2179.5-82.661.9000110.9A194 L204 S236 F238 F256 S260 A263 A264 L267A194-L258 HydrophobicContact CB-CD1 3.71Å; A194-L258 HydrophobicContact CB-CG 4.17Å; L204-L258 HydrophobicContact CD1-CD1 4.25Å; S236-L258 VanDerWaalsContact CB-O 3.3Å; S236-L258 WeakPolarHBondContact CB-O 3.43Å; S236-L258 WeakPolarHBondContact O-CA 3.49Å; S236-L258 WeakPolarHBondContact O-CB 3.4Å; S236-L258 PolarHBondContact O-N 3.35Å; S236-L258 PolarHBondContact OG-O 3.43Å; F238-L258 HydrophobicContact CB-CD1 3.95Å; F256-L258 HydrophobicContact CB-CD1 4.12Å; L258-S260 PolarHBondContact O-N 3.16Å; L258-S260 VanDerWaalsContact O-N 3.12Å; L258-A263 HydrophobicContact CB-CB 4.22Å; L258-A263 HydrophobicContact CD2-CB 4.48Å; L258-A264 HydrophobicContact CB-CB 4.23Å; L258-A264 VanDerWaalsContact CD2-CA 3.43Å; L258-A264 HydrophobicContact CD2-CB 4.14Å; L258-L267 HydrophobicContact CD1-CD2 4.28Å; L258-L267 HydrophobicContact CD2-CB 3.78Å; L258-L267 HydrophobicContact CD2-CD2 3.58Å; L258-L267 HydrophobicContact CD2-CG 4.33Å
259P95.7Very high89Confident99 Ų9967.7 Ų67.764%0.64332%0.324SS*.SBendtrans-60-26.2-175.9-2734.4000114.4K193K193-P259 HydrophobicContact CB-CG 4.46Å; K193-P259 VanDerWaalsContact O-CD 3.24Å; K193-P259 WeakPolarHBondContact O-CD 2.99Å
260S95.7Very high90.9Very high50 Ų5060.3 Ų60.335%0.3529%0.29SS..SBendtrans-156.3165.9-179.969.40000112.4S236 L258 R262 A263 A264S236-S260 VanDerWaalsContact CB-C 3.48Å; L258-S260 PolarHBondContact O-N 3.16Å; L258-S260 VanDerWaalsContact O-N 3.12Å; S260-R262 PolarHBondContact O-N 2.97Å; S260-R262 PolarHBondContact OG-N 3.35Å; S260-A263 PolarHBondContact O-N 3.26Å; S260-A263 PolarHBondContact OG-N 2.86Å; S260-A263 VanDerWaalsContact OG-N 3.1Å; S260-A264 PolarHBondContact O-N 3.5Å
261Y95.1Very high93Very high113 Ų11352.2 Ų52.244%0.44326%0.259SS..Hα-helixtrans-55.7-38.8168.9166.1-95.5000112.3Y233 R235 A264 K265Y233-Y261 HydrophobicContact CD2-CE2 4.43Å; Y233-Y261 HydrophobicContact CE2-CD2 4.11Å; Y233-Y261 AromaticContact CE2-CE2 3.55Å; Y233-Y261 HydrophobicContact CE2-CE2 3.55Å; R235-Y261 WeakPolarHBondContact O-CA 3.38Å; R235-Y261 WeakPolarHBondContact O-CD2 3.26Å; Y261-A264 PolarHBondContact O-N 3.26Å; Y261-K265 HydrophobicContact CE1-CD 4.07Å; Y261-K265 WeakPolarHBondContact O-CB 3.45Å; Y261-K265 PolarHBondContact O-N 2.7Å
262R92.3Very high94.1Very high211 Ų21148.6 Ų48.680%0.79624%0.243SC*.Hα-helixtrans-65.5-42.5179.1-68.1-176.3-175.9159.62.7111.2S260 K265 K266S260-R262 PolarHBondContact O-N 2.97Å; S260-R262 PolarHBondContact OG-N 3.35Å; R262-K265 PolarHBondContact O-N 3.27Å; R262-K266 WeakPolarHBondContact O-CB 3.16Å; R262-K266 PolarHBondContact O-N 2.65Å
263A94.8Very high94.7Very high25 Ų2546.9 Ų46.921%0.20723%0.23CC..Hα-helixtrans-62.8-45.4175.100000111.5L258 S260 K265 K266 L267L258-A263 HydrophobicContact CB-CB 4.22Å; L258-A263 HydrophobicContact CD2-CB 4.48Å; S260-A263 PolarHBondContact O-N 3.26Å; S260-A263 PolarHBondContact OG-N 2.86Å; S260-A263 VanDerWaalsContact OG-N 3.1Å; A263-K265 PolarHBondContact O-N 2.91Å; A263-K266 WeakPolarHBondContact O-CB 3.47Å; A263-K266 PolarHBondContact O-N 2.83Å; A263-L267 PolarHBondContact O-N 2.88Å
264A96.1Very high95.1Very high0 Ų043 Ų430%021%0.205CC..Hα-helixtrans-60.4-44.3176.900000112.8Y233 L258 S260 Y261 W268Y233-A264 HydrophobicContact CD2-CB 4.15Å; L258-A264 HydrophobicContact CB-CB 4.23Å; L258-A264 VanDerWaalsContact CD2-CA 3.43Å; L258-A264 HydrophobicContact CD2-CB 4.14Å; S260-A264 PolarHBondContact O-N 3.5Å; Y261-A264 PolarHBondContact O-N 3.26Å; A264-W268 VanDerWaalsContact O-CB 3.28Å; A264-W268 WeakPolarHBondContact O-CB 3.47Å; A264-W268 PolarHBondContact O-N 3.44Å
265K94.1Very high95.2Very high68 Ų6843 Ų4330%0.29620%0.204SC..Hα-helixtrans-64.4-39174.7-175.4174.1-172.4171.60112.3Y233 Y261 R262 A263 K269Y233-K265 HydrophobicContact CD2-CB 4.43Å; Y233-K265 HydrophobicContact CE2-CB 3.74Å; Y233-K265 HydrophobicContact CE2-CG 4.19Å; Y261-K265 HydrophobicContact CE1-CD 4.07Å; Y261-K265 WeakPolarHBondContact O-CB 3.45Å; Y261-K265 PolarHBondContact O-N 2.7Å; R262-K265 PolarHBondContact O-N 3.27Å; A263-K265 PolarHBondContact O-N 2.91Å; K265-K269 WeakPolarHBondContact O-CG 3.48Å; K265-K269 PolarHBondContact O-N 3.33Å
266K93.6Very high95.1Very high51 Ų5143.8 Ų43.822%0.22221%0.208CC..Hα-helixtrans-62.3-55.2177-175.5-173.9-179.2-175.90110.4S52 K53 R262 A263 W268 K269 V270S52-K266 PolarHBondContact OG-NZ 3.46Å; K53-K266 WeakPolarHBondContact O-CE 3.29Å; K53-K266 PolarHBondContact O-NZ 3.27Å; R262-K266 WeakPolarHBondContact O-CB 3.16Å; R262-K266 PolarHBondContact O-N 2.65Å; A263-K266 WeakPolarHBondContact O-CB 3.47Å; A263-K266 PolarHBondContact O-N 2.83Å; K266-W268 VanDerWaalsContact C-N 3.33Å; K266-W268 PolarHBondContact O-N 3.28Å; K266-K269 WeakPolarHBondContact O-CB 3.48Å; K266-K269 PolarHBondContact O-N 3.16Å; K266-K269 VanDerWaalsContact O-N 3.15Å; K266-V270 WeakPolarHBondContact O-CG2 3.3Å; K266-V270 PolarHBondContact O-N 2.59Å
267L96.1Very high95Very high0 Ų043.2 Ų43.20%021%0.206CC..Hα-helixtrans-55.5-49.5176.8173.863.7000110.7H192 L204 V206 F238 L258 A263 K269 V270 C271H192-L267 HydrophobicContact CB-CD1 4.25Å; H192-L267 VanDerWaalsContact CD2-CD1 3.47Å; H192-L267 WeakPolarHBondContact CD2-CD1 3.39Å; L204-L267 HydrophobicContact CB-CD2 4.49Å; L204-L267 HydrophobicContact CD1-CD2 3.49Å; L204-L267 VanDerWaalsContact CD1-CD2 3.49Å; V206-L267 HydrophobicContact CG2-CD1 3.54Å; F238-L267 HydrophobicContact CB-CD2 4.31Å; F238-L267 HydrophobicContact CD1-CD2 3.69Å; F238-L267 HydrophobicContact CD2-CD2 3.96Å; F238-L267 HydrophobicContact CD2-CG 4.14Å; F238-L267 HydrophobicContact CE1-CD2 3.94Å; F238-L267 HydrophobicContact CE1-CG 4.46Å; F238-L267 HydrophobicContact CE2-CD2 4.17Å; F238-L267 HydrophobicContact CE2-CG 4.03Å; F238-L267 HydrophobicContact CG-CD2 3.72Å; F238-L267 HydrophobicContact CG-CG 4.4Å; F238-L267 HydrophobicContact CZ-CD2 4.16Å; F238-L267 HydrophobicContact CZ-CG 4.2Å; L258-L267 HydrophobicContact CD1-CD2 4.28Å; L258-L267 HydrophobicContact CD2-CB 3.78Å; L258-L267 HydrophobicContact CD2-CD2 3.58Å; L258-L267 HydrophobicContact CD2-CG 4.33Å; A263-L267 PolarHBondContact O-N 2.88Å; L267-K269 VanDerWaalsContact C-N 3.3Å; L267-K269 PolarHBondContact O-N 2.99Å; L267-V270 PolarHBondContact O-N 3.38Å; L267-V270 VanDerWaalsContact O-N 3.1Å; L267-C271 VanDerWaalsContact CD1-SG 3.54Å; L267-C271 PolarHBondContact O-N 2.81Å; L267-C271 PolarHBondContact O-SG 2.94Å
268W95.9Very high94.9Very high19 Ų1939.9 Ų39.97%0.07219%0.191CC..Hα-helixtrans-55.4-43.3178.217281.2000113.1I231 Y233 F238 A264 K266 V272 S296 F298I231-W268 PolarHBondContact O-NE1 2.82Å; Y233-W268 HydrophobicContact CD1-CB 3.61Å; Y233-W268 AromaticContact CD1-CD1 3.71Å; Y233-W268 AromaticContact CD1-CD2 3.59Å; Y233-W268 HydrophobicContact CD1-CD2 3.59Å; Y233-W268 HydrophobicContact CD1-CE3 4.11Å; Y233-W268 AromaticContact CD1-CG 3.32Å; Y233-W268 HydrophobicContact CD1-CG 3.32Å; Y233-W268 HydrophobicContact CE1-CB 4.21Å; Y233-W268 AromaticContact CE1-CD2 3.52Å; Y233-W268 HydrophobicContact CE1-CD2 3.52Å; Y233-W268 AromaticContact CE1-CE3 3.59Å; Y233-W268 HydrophobicContact CE1-CE3 3.59Å; Y233-W268 AromaticContact CE1-CG 3.79Å; Y233-W268 HydrophobicContact CE1-CG 3.79Å; Y233-W268 HydrophobicContact CE1-CZ3 4.23Å; Y233-W268 HydrophobicContact CG-CB 4.09Å; Y233-W268 HydrophobicContact CG-CG 4.24Å; F238-W268 HydrophobicContact CD2-CB 4.25Å; F238-W268 HydrophobicContact CE2-CB 4.19Å; A264-W268 VanDerWaalsContact O-CB 3.28Å; A264-W268 WeakPolarHBondContact O-CB 3.47Å; A264-W268 PolarHBondContact O-N 3.44Å; K266-W268 VanDerWaalsContact C-N 3.33Å; K266-W268 PolarHBondContact O-N 3.28Å; W268-V272 HydrophobicContact CD2-CG2 4.3Å; W268-V272 HydrophobicContact CZ2-CG2 4.03Å; W268-V272 VanDerWaalsContact O-CG2 3.29Å; W268-V272 WeakPolarHBondContact O-CG2 3.4Å; W268-V272 PolarHBondContact O-N 3.41Å; W268-S296 VanDerWaalsContact CH2-OG 3.25Å; W268-S296 WeakPolarHBondContact CH2-OG 3.38Å; W268-S296 WeakPolarHBondContact CZ3-OG 3.27Å; W268-F298 HydrophobicContact CH2-CB 3.84Å; W268-F298 HydrophobicContact CH2-CD1 4.03Å; W268-F298 HydrophobicContact CH2-CG 4.42Å; W268-F298 HydrophobicContact CZ3-CB 3.76Å; W268-F298 AromaticContact CZ3-CD1 3.82Å; W268-F298 HydrophobicContact CZ3-CD1 3.82Å; W268-F298 HydrophobicContact CZ3-CG 4.16Å
269K94.1Very high94.6Very high52 Ų5245.4 Ų45.423%0.22621%0.212CC..Hα-helixtrans-62-50.3174.9-76.8-175.7169.5-162.10111.5K265 K266 L267 C271 V272 E273 F298K265-K269 WeakPolarHBondContact O-CG 3.48Å; K265-K269 PolarHBondContact O-N 3.33Å; K266-K269 WeakPolarHBondContact O-CB 3.48Å; K266-K269 PolarHBondContact O-N 3.16Å; K266-K269 VanDerWaalsContact O-N 3.15Å; L267-K269 VanDerWaalsContact C-N 3.3Å; L267-K269 PolarHBondContact O-N 2.99Å; K269-C271 VanDerWaalsContact C-N 3.28Å; K269-C271 PolarHBondContact O-N 3.17Å; K269-V272 PolarHBondContact O-N 2.94Å; K269-V272 VanDerWaalsContact O-N 3.15Å; K269-E273 VanDerWaalsContact O-CG 3.29Å; K269-E273 WeakPolarHBondContact O-CG 3.4Å; K269-E273 PolarHBondContact O-N 3.06Å; K269-F298 HydrophobicContact CB-CD1 4.42Å; K269-F298 HydrophobicContact CB-CE1 4.06Å; K269-F298 HydrophobicContact CB-CZ 4.46Å; K269-F298 HydrophobicContact CD-CD1 4.49Å; K269-F298 HydrophobicContact CD-CD2 4.41Å; K269-F298 HydrophobicContact CD-CE1 4.48Å; K269-F298 HydrophobicContact CD-CE2 4.4Å; K269-F298 HydrophobicContact CD-CG 4.45Å; K269-F298 HydrophobicContact CD-CZ 4.43Å; K269-F298 HydrophobicContact CG-CD1 3.8Å; K269-F298 HydrophobicContact CG-CE1 3.89Å; K269-F298 HydrophobicContact CG-CG 4.15Å; K269-F298 HydrophobicContact CG-CZ 4.31Å
270V95.4Very high94.2Very high4 Ų443 Ų432%0.02419%0.193CC..Hα-helixtrans-56.1-45.1-180174.10000110.5D190 V206 K266 L267 E273 H274D190-V270 HydrophobicContact CB-CG1 4.35Å; V206-V270 HydrophobicContact CB-CG1 3.95Å; V206-V270 HydrophobicContact CG1-CG1 3.95Å; V206-V270 HydrophobicContact CG2-CG1 4.19Å; K266-V270 WeakPolarHBondContact O-CG2 3.3Å; K266-V270 PolarHBondContact O-N 2.59Å; L267-V270 PolarHBondContact O-N 3.38Å; L267-V270 VanDerWaalsContact O-N 3.1Å; V270-E273 PolarHBondContact O-N 2.86Å; V270-H274 WeakPolarHBondContact O-CB 3.44Å; V270-H274 PolarHBondContact O-N 3.41Å; V270-H274 PolarHBondContact O-ND1 3.38Å
271C96.4Very high93.8Very high0 Ų045.9 Ų45.90%021%0.209CC..Hα-helixtrans-63.9-43.9177.1-560000112.9L211 W225 I231 L267 K269 E273 H275L211-C271 HydrophobicContact CD1-CB 4.36Å; W225-C271 HydrophobicContact CH2-CB 4.25Å; I231-C271 HydrophobicContact CD1-CB 3.69Å; I231-C271 HydrophobicContact CG2-CB 4.11Å; L267-C271 VanDerWaalsContact CD1-SG 3.54Å; L267-C271 PolarHBondContact O-N 2.81Å; L267-C271 PolarHBondContact O-SG 2.94Å; K269-C271 VanDerWaalsContact C-N 3.28Å; K269-C271 PolarHBondContact O-N 3.17Å; C271-E273 VanDerWaalsContact C-N 3.34Å; C271-H275 WeakPolarHBondContact O-CB 3.07Å; C271-H275 PolarHBondContact O-N 2.99Å
272V93.3Very high93.2Very high26 Ų2643.3 Ų43.316%0.15821%0.207CC..Hα-helixtrans-61.6-45177.2166.90000110.4W268 K269 T276 F298W268-V272 HydrophobicContact CD2-CG2 4.3Å; W268-V272 HydrophobicContact CZ2-CG2 4.03Å; W268-V272 VanDerWaalsContact O-CG2 3.29Å; W268-V272 WeakPolarHBondContact O-CG2 3.4Å; W268-V272 PolarHBondContact O-N 3.41Å; K269-V272 PolarHBondContact O-N 2.94Å; K269-V272 VanDerWaalsContact O-N 3.15Å; V272-T276 WeakPolarHBondContact O-CB 3.35Å; V272-T276 PolarHBondContact O-N 3.31Å; V272-T276 PolarHBondContact O-OG1 3.45Å; V272-T276 VanDerWaalsContact O-OG1 3.07Å; V272-F298 HydrophobicContact CG1-CE1 4.36Å
273E94.5Very high92.6Very high17 Ų1735.1 Ų35.18%0.07918%0.181CC..Hα-helixtrans-63.6-48.2178.5-67-176132.300111.9K78 F79 K269 V270 C271 T276 F277 F298 Y300K78-E273 VanDerWaalsContact CE-OE2 3.24Å; K78-E273 WeakPolarHBondContact CE-OE2 3.06Å; K78-E273 IonicContact NZ-OE1 2.82Å; K78-E273 PolarHBondContact NZ-OE1 2.99Å; K78-E273 IonicContact NZ-OE2 2.72Å; K78-E273 PolarHBondContact NZ-OE2 3.1Å; K78-E273 VanDerWaalsContact NZ-OE2 3.14Å; F79-E273 HydrophobicContact CE1-CB 4.13Å; F79-E273 HydrophobicContact CZ-CB 4.05Å; K269-E273 VanDerWaalsContact O-CG 3.29Å; K269-E273 WeakPolarHBondContact O-CG 3.4Å; K269-E273 PolarHBondContact O-N 3.06Å; V270-E273 PolarHBondContact O-N 2.86Å; C271-E273 VanDerWaalsContact C-N 3.34Å; E273-T276 PolarHBondContact O-N 2.99Å; E273-F277 VanDerWaalsContact O-CB 3.24Å; E273-F277 WeakPolarHBondContact O-CB 3.19Å; E273-F277 PolarHBondContact O-N 3.1Å; E273-F298 HydrophobicContact CG-CE1 3.89Å; E273-F298 HydrophobicContact CG-CZ 3.76Å; E273-F298 WeakPolarHBondContact OE1-CZ 3.45Å; E273-Y300 HydrophobicContact CB-CD2 4.1Å; E273-Y300 HydrophobicContact CG-CD2 3.89Å
274H96.2Very high91.1Very high7 Ų740.3 Ų40.33%0.03221%0.205CC..Hα-helixtrans-65.9-44.2179.9-78.668.7000112.3F79 V206 W225 V270 F277 F278F79-H274 AromaticContact CE1-ND1 3.96Å; V206-H274 HydrophobicContact CG1-CB 3.97Å; W225-H274 HydrophobicContact CH2-CB 4.48Å; W225-H274 HydrophobicContact CZ2-CB 3.76Å; V270-H274 WeakPolarHBondContact O-CB 3.44Å; V270-H274 PolarHBondContact O-N 3.41Å; V270-H274 PolarHBondContact O-ND1 3.38Å; H274-F277 PolarHBondContact O-N 3.37Å; H274-F278 HydrophobicContact CB-CD2 4.42Å; H274-F278 AromaticContact CD2-CE2 3.84Å; H274-F278 WeakPolarHBondContact O-CB 3.35Å; H274-F278 WeakPolarHBondContact O-CD2 3.41Å; H274-F278 PolarHBondContact O-N 3.48Å
275H93.6Very high89.1Confident41 Ų4146.4 Ų46.419%0.1924%0.242CC..Hα-helixtrans-59.8-51.2175.1177.4-82.4000110.2W225 C271 F277 R279W225-H275 HydrophobicContact CD2-CB 4.31Å; W225-H275 HydrophobicContact CE3-CB 4.15Å; W225-H275 HydrophobicContact CZ3-CB 4.37Å; C271-H275 WeakPolarHBondContact O-CB 3.07Å; C271-H275 PolarHBondContact O-N 2.99Å; H275-F277 PolarHBondContact O-N 3.28Å; H275-R279 WeakPolarHBondContact O-CA 3.26Å; H275-R279 WeakPolarHBondContact O-CB 3.41Å; H275-R279 PolarHBondContact O-N 3.46Å
276T92.6Very high87.2Confident20 Ų2050.5 Ų50.512%0.12327%0.266CS..Hα-helixtrans-61-45.2179.2-64.90000112V272 E273 L280 T283 Y300 T304V272-T276 WeakPolarHBondContact O-CB 3.35Å; V272-T276 PolarHBondContact O-N 3.31Å; V272-T276 PolarHBondContact O-OG1 3.45Å; V272-T276 VanDerWaalsContact O-OG1 3.07Å; E273-T276 PolarHBondContact O-N 2.99Å; T276-L280 HydrophobicContact CG2-CD1 4.13Å; T276-L280 WeakPolarHBondContact O-CB 3.32Å; T276-L280 PolarHBondContact O-N 2.9Å; T276-T283 HydrophobicContact CG2-CG2 4.08Å; T276-Y300 HydrophobicContact CG2-CD1 3.47Å; T276-Y300 VanDerWaalsContact CG2-CD1 3.47Å; T276-Y300 HydrophobicContact CG2-CE1 4.33Å; T276-Y300 HydrophobicContact CG2-CG 4.12Å; T276-T304 HydrophobicContact CG2-CG2 4.4Å; T276-T304 WeakPolarHBondContact O-CG2 3.49Å
277F95.4Very high85Confident0 Ų053 Ų530%029%0.288CS..Hα-helixtrans-64.7-50.6-177.4-175.3-101.2000112.5D40 Y41 F79 E273 H274 H275 Y300 R303 Q305D40-F277 HydrophobicContact CB-CE2 3.92Å; Y41-F277 HydrophobicContact CD1-CE1 4.03Å; Y41-F277 AromaticContact CD1-CZ 3.82Å; Y41-F277 HydrophobicContact CD1-CZ 3.82Å; Y41-F277 AromaticContact CE1-CE1 3.85Å; Y41-F277 HydrophobicContact CE1-CE1 3.85Å; Y41-F277 AromaticContact CE1-CZ 3.71Å; Y41-F277 HydrophobicContact CE1-CZ 3.71Å; F79-F277 HydrophobicContact CB-CD1 3.67Å; F79-F277 HydrophobicContact CB-CE1 3.47Å; F79-F277 VanDerWaalsContact CB-CE1 3.47Å; F79-F277 HydrophobicContact CB-CG 4.41Å; F79-F277 HydrophobicContact CB-CZ 4.08Å; F79-F277 HydrophobicContact CD1-CB 4.02Å; F79-F277 AromaticContact CD1-CD1 3.79Å; F79-F277 HydrophobicContact CD1-CD1 3.79Å; F79-F277 HydrophobicContact CD1-CE1 4.46Å; F79-F277 AromaticContact CD1-CG 3.93Å; F79-F277 HydrophobicContact CD1-CG 3.93Å; F79-F277 HydrophobicContact CD2-CD1 4.1Å; F79-F277 HydrophobicContact CD2-CD2 4.02Å; F79-F277 HydrophobicContact CD2-CE1 4.21Å; F79-F277 HydrophobicContact CD2-CE2 4.15Å; F79-F277 AromaticContact CD2-CG 3.99Å; F79-F277 HydrophobicContact CD2-CG 3.99Å; F79-F277 HydrophobicContact CD2-CZ 4.23Å; F79-F277 HydrophobicContact CE1-CB 3.8Å; F79-F277 HydrophobicContact CE1-CD1 4.42Å; F79-F277 HydrophobicContact CE1-CG 4.11Å; F79-F277 HydrophobicContact CE2-CB 4.45Å; F79-F277 HydrophobicContact CE2-CD2 4.09Å; F79-F277 HydrophobicContact CE2-CG 4.16Å; F79-F277 HydrophobicContact CG-CB 4.43Å; F79-F277 AromaticContact CG-CD1 3.58Å; F79-F277 HydrophobicContact CG-CD1 3.58Å; F79-F277 HydrophobicContact CG-CD2 4.33Å; F79-F277 AromaticContact CG-CE1 3.82Å; F79-F277 HydrophobicContact CG-CE1 3.82Å; F79-F277 AromaticContact CG-CG 3.85Å; F79-F277 HydrophobicContact CG-CG 3.85Å; F79-F277 HydrophobicContact CG-CZ 4.3Å; F79-F277 HydrophobicContact CZ-CB 4.02Å; F79-F277 HydrophobicContact CZ-CD2 4.47Å; F79-F277 HydrophobicContact CZ-CG 4.21Å; E273-F277 VanDerWaalsContact O-CB 3.24Å; E273-F277 WeakPolarHBondContact O-CB 3.19Å; E273-F277 PolarHBondContact O-N 3.1Å; H274-F277 PolarHBondContact O-N 3.37Å; H275-F277 PolarHBondContact O-N 3.28Å; F277-Y300 HydrophobicContact CD2-CE1 4.42Å; F277-Y300 WeakPolarHBondContact CD2-OH 3.37Å; F277-R303 VanDerWaalsContact CD2-O 3.26Å; F277-R303 WeakPolarHBondContact CD2-O 3.34Å; F277-R303 WeakPolarHBondContact CE2-O 3.5Å; F277-Q305 HydrophobicContact CD1-CB 4.16Å; F277-Q305 HydrophobicContact CE1-CB 3.86Å; F277-Q305 HydrophobicContact CE1-CG 4.31Å; F277-Q305 HydrophobicContact CE2-CB 4.48Å; F277-Q305 HydrophobicContact CZ-CB 4.04Å; F277-Q305 VanDerWaalsContact O-CB 3.26Å; F277-Q305 WeakPolarHBondContact O-CB 3.38Å; F277-Q305 PolarHBondContact O-N 3.4Å
278F94.8Very high82.7Confident29 Ų2963.4 Ų63.413%0.12733%0.333CS..Hα-helixtrans-89.6-26.7-172.9-68.9-68.9000114.5F79 Y80 S208 H274F79-F278 HydrophobicContact CB-CE2 4.06Å; F79-F278 HydrophobicContact CB-CZ 3.73Å; F79-F278 AromaticContact CD1-CE2 3.89Å; F79-F278 HydrophobicContact CD1-CE2 3.89Å; F79-F278 HydrophobicContact CD1-CZ 4.43Å; F79-F278 HydrophobicContact CG-CE2 4.41Å; Y80-F278 VanDerWaalsContact O-CZ 3.24Å; Y80-F278 WeakPolarHBondContact O-CZ 3.26Å; S208-F278 VanDerWaalsContact CA-CD2 3.49Å; H274-F278 HydrophobicContact CB-CD2 4.42Å; H274-F278 AromaticContact CD2-CE2 3.84Å; H274-F278 WeakPolarHBondContact O-CB 3.35Å; H274-F278 WeakPolarHBondContact O-CD2 3.41Å; H274-F278 PolarHBondContact O-N 3.48Å
279R91.4Very high80.6Confident121 Ų12167.5 Ų67.546%0.45736%0.364SS..Hα-helixtrans-98.3-37.1-173.4179.459.1-171.7118.8-7.8114W225 H275W225-R279 HydrophobicContact CB-CB 4.24Å; W225-R279 HydrophobicContact CB-CG 4.47Å; H275-R279 WeakPolarHBondContact O-CA 3.26Å; H275-R279 WeakPolarHBondContact O-CB 3.41Å; H275-R279 PolarHBondContact O-N 3.46Å
280L87.9Confident78.5Confident49 Ų4973.9 Ų73.926%0.25739%0.392SS..  trans-89.6145.4-172.5-55.8-173000111.2T276 S282 T304T276-L280 HydrophobicContact CG2-CD1 4.13Å; T276-L280 WeakPolarHBondContact O-CB 3.32Å; T276-L280 PolarHBondContact O-N 2.9Å; L280-S282 WeakPolarHBondContact CB-O 3.41Å; L280-T304 HydrophobicContact CB-CG2 4.33Å; L280-T304 VanDerWaalsContact O-CB 3.22Å; L280-T304 WeakPolarHBondContact O-CB 3.23Å; L280-T304 WeakPolarHBondContact O-CG2 3.35Å; L280-T304 PolarHBondContact O-OG1 3.34Å
281T86.1Confident76.2Confident111 Ų11182.8 Ų82.868%0.68143%0.431SS*.SBendtrans-77.5-25.3175.751.90000112.2T304T281-T304 PolarHBondContact O-OG1 2.85Å
282S82.8Confident74.2Confident58 Ų5890.5 Ų90.541%0.40647%0.471SS..SBendtrans-148.2161174.360.40000110.4L280 T304L280-S282 WeakPolarHBondContact CB-O 3.41Å; S282-T304 VanDerWaalsContact C-CG2 3.41Å
283T79.2Confident72.1Confident39 Ų3992.7 Ų92.724%0.23949%0.492CS..PPolyproline II helixtrans-73.7133.3169.155.10000110.1T276 T285 Y300 G302 T304T276-T283 HydrophobicContact CG2-CG2 4.08Å; T283-T285 PolarHBondContact O-N 3.29Å; T283-T285 VanDerWaalsContact O-N 3.14Å; T283-Y300 HydrophobicContact CG2-CD1 3.93Å; T283-Y300 HydrophobicContact CG2-CE1 4.29Å; T283-G302 WeakPolarHBondContact CG2-O 3.43Å; T283-T304 HydrophobicContact CG2-CG2 4.14Å
284D63.9Low69.9Low134 Ų134100.8 Ų100.872%0.71754%0.535SS*.PPolyproline II helixtrans-49.1122.5175.7-73-25.7000111I286D284-I286 PolarHBondContact O-N 2.9Å
285T53.3Low68.1Low128 Ų128103.2 Ų103.279%0.78556%0.562SS**PPolyproline II helixtrans-63.9130.5169.855.10000108T283 P287T283-T285 PolarHBondContact O-N 3.29Å; T283-T285 VanDerWaalsContact O-N 3.14Å; T285-P287 WeakPolarHBondContact O-CD 3.44Å
286I54.2Low66.6Low154 Ų154103 Ų10379%0.7957%0.565SS**  trans-52.2113-179.8-59.8167.7000107.6D284 K288D284-I286 PolarHBondContact O-N 2.9Å; I286-K288 PolarHBondContact O-N 2.9Å
287P48.9Very low65.6Low105 Ų105110.1 Ų110.168%0.68259%0.594SS**  trans-60.4121.7170.3-17.730.8000106.1T285 S289T285-P287 WeakPolarHBondContact O-CD 3.44Å; P287-S289 PolarHBondContact O-N 3.5Å
288K46.8Very low64.9Low218 Ų218111 Ų11195%0.94860%0.598SS**  trans-64.181.1171.8-68.2-178.8-178.2175.90107.6I286I286-K288 PolarHBondContact O-N 2.9Å
289S51.1Low64.2Low105 Ų105117.5 Ų117.573%0.73462%0.622SS**  trans-125143.2-178-167.20000113.4P287P287-S289 PolarHBondContact O-N 3.5Å
290K50.6Low63.9Low185 Ų185113 Ų11380%0.80461%0.605SS**  trans-81.7145.4-164.9-60.9172.9175.4176.10110.5
291F47.5Very low63.6Low192 Ų192114.3 Ų114.384%0.84262%0.618SS**SBendtrans64.2132.5166.2-76.1-87.1000119.8A293F291-A293 PolarHBondContact O-N 3.44Å
292L54.2Low63.7Low161 Ų161109.9 Ų109.984%0.84360%0.595SS**  trans583.2165.4-59.7169.8000117.8L294L292-L294 PolarHBondContact O-N 2.9Å
293A49.4Very low64.2Low72 Ų72110.9 Ų110.960%0.59559%0.59SS**  trans-73.8111.3164.600000110.8F291 G295F291-A293 PolarHBondContact O-N 3.44Å; A293-G295 PolarHBondContact O-N 3.25Å
294L48.9Very low65Low187 Ų187109 Ų10998%0.97958%0.578SS**  trans-77.596.9171-138.589.9000108.9L292L292-L294 PolarHBondContact O-N 2.9Å
295G56.8Low66.4Low58 Ų58103.3 Ų103.360%0.59855%0.547SS*.SBendtrans163.8173.3-179.200000113.6A293 K297A293-G295 PolarHBondContact O-N 3.25Å; G295-K297 PolarHBondContact O-N 3.4Å; G295-K297 VanDerWaalsContact O-N 3.13Å
296S63.6Low68.4Low37 Ų3798.9 Ų98.926%0.25952%0.524SS..  trans-65.1112.6173.9-175.70000110.1W268 F298W268-S296 VanDerWaalsContact CH2-OG 3.25Å; W268-S296 WeakPolarHBondContact CH2-OG 3.38Å; W268-S296 WeakPolarHBondContact CZ3-OG 3.27Å; S296-F298 PolarHBondContact O-N 3.25Å
297K70.6Confident70.3Confident169 Ų16994.2 Ų94.274%0.73550%0.499SS*.  trans-75.43.8175.1-60.9-175.1-179.3-178.80113.8G295 R299G295-K297 PolarHBondContact O-N 3.4Å; G295-K297 VanDerWaalsContact O-N 3.13Å; K297-R299 PolarHBondContact O-N 3.49Å
298F80.9Confident72.5Confident20 Ų2089.2 Ų89.29%0.08847%0.466CS..  trans-62.9135.4-179.1175.7-94.6000110.4W268 K269 V272 E273 S296W268-F298 HydrophobicContact CH2-CB 3.84Å; W268-F298 HydrophobicContact CH2-CD1 4.03Å; W268-F298 HydrophobicContact CH2-CG 4.42Å; W268-F298 HydrophobicContact CZ3-CB 3.76Å; W268-F298 AromaticContact CZ3-CD1 3.82Å; W268-F298 HydrophobicContact CZ3-CD1 3.82Å; W268-F298 HydrophobicContact CZ3-CG 4.16Å; K269-F298 HydrophobicContact CB-CD1 4.42Å; K269-F298 HydrophobicContact CB-CE1 4.06Å; K269-F298 HydrophobicContact CB-CZ 4.46Å; K269-F298 HydrophobicContact CD-CD1 4.49Å; K269-F298 HydrophobicContact CD-CD2 4.41Å; K269-F298 HydrophobicContact CD-CE1 4.48Å; K269-F298 HydrophobicContact CD-CE2 4.4Å; K269-F298 HydrophobicContact CD-CG 4.45Å; K269-F298 HydrophobicContact CD-CZ 4.43Å; K269-F298 HydrophobicContact CG-CD1 3.8Å; K269-F298 HydrophobicContact CG-CE1 3.89Å; K269-F298 HydrophobicContact CG-CG 4.15Å; K269-F298 HydrophobicContact CG-CZ 4.31Å; V272-F298 HydrophobicContact CG1-CE1 4.36Å; E273-F298 HydrophobicContact CG-CE1 3.89Å; E273-F298 HydrophobicContact CG-CZ 3.76Å; E273-F298 WeakPolarHBondContact OE1-CZ 3.45Å; S296-F298 PolarHBondContact O-N 3.25Å
299R79.8Confident74.7Confident164 Ų16483.1 Ų83.162%0.61944%0.437SS*.  trans-140.1144.5175.2-64.8-65-178.3-98.95106.9K297K297-R299 PolarHBondContact O-N 3.49Å
300Y85.9Confident76.8Confident27 Ų2784.5 Ų84.511%0.10643%0.432CS..  trans-66.1139.7166.6-179.6-105.9000108.8F79 E273 T276 F277 T283 G302 R303F79-Y300 AromaticContact CE2-CE2 3.96Å; F79-Y300 HydrophobicContact CE2-CE2 3.96Å; F79-Y300 HydrophobicContact CZ-CD2 4.46Å; F79-Y300 AromaticContact CZ-CE2 3.74Å; F79-Y300 HydrophobicContact CZ-CE2 3.74Å; E273-Y300 HydrophobicContact CB-CD2 4.1Å; E273-Y300 HydrophobicContact CG-CD2 3.89Å; T276-Y300 HydrophobicContact CG2-CD1 3.47Å; T276-Y300 VanDerWaalsContact CG2-CD1 3.47Å; T276-Y300 HydrophobicContact CG2-CE1 4.33Å; T276-Y300 HydrophobicContact CG2-CG 4.12Å; F277-Y300 HydrophobicContact CD2-CE1 4.42Å; F277-Y300 WeakPolarHBondContact CD2-OH 3.37Å; T283-Y300 HydrophobicContact CG2-CD1 3.93Å; T283-Y300 HydrophobicContact CG2-CE1 4.29Å; Y300-G302 VanDerWaalsContact CE1-C 3.48Å; Y300-G302 WeakPolarHBondContact CE1-O 3.3Å; Y300-R303 WeakPolarHBondContact CE1-O 3.45Å; Y300-R303 PolarHBondContact OH-O 3.48Å
301S82.1Confident78.8Confident76 Ų7677.1 Ų77.153%0.53141%0.405SS..  trans-131.63.1-171.153.10000114.2
302G87.8Confident81Confident19 Ų1968.1 Ų68.120%0.19637%0.366CS..SBendtrans-86.6-178.1171.600000111.9T283 Y300T283-G302 WeakPolarHBondContact CG2-O 3.43Å; Y300-G302 VanDerWaalsContact CE1-C 3.48Å; Y300-G302 WeakPolarHBondContact CE1-O 3.3Å
303R92.9Very high82.9Confident78 Ų7864.5 Ų64.529%0.29436%0.359SS..  trans-71.7148174.1-65.9-176.2-69.8-165.4-1.3110.3D40 F277 Y300 Q307D40-R303 WeakPolarHBondContact OD1-CB 3.21Å; D40-R303 PolarHBondContact OD1-N 2.8Å; D40-R303 IonicContact OD1-NE 2.73Å; D40-R303 IonicContact OD2-CZ 2.93Å; D40-R303 IonicContact OD2-NE 3.6Å; D40-R303 PolarHBondContact OD2-NE 2.87Å; D40-R303 IonicContact OD2-NH2 2.6Å; D40-R303 PolarHBondContact OD2-NH2 2.86Å; F277-R303 VanDerWaalsContact CD2-O 3.26Å; F277-R303 WeakPolarHBondContact CD2-O 3.34Å; F277-R303 WeakPolarHBondContact CE2-O 3.5Å; Y300-R303 WeakPolarHBondContact CE1-O 3.45Å; Y300-R303 PolarHBondContact OH-O 3.48Å; R303-Q307 HydrophobicContact CB-CB 3.88Å; R303-Q307 HydrophobicContact CG-CB 4.32Å
304T95.1Very high85Confident0 Ų067.9 Ų67.90%037%0.367CS..  trans-70.2167.2166.365.10000110.4T276 L280 T281 S282 T283 A306 Q307 T308T276-T304 HydrophobicContact CG2-CG2 4.4Å; T276-T304 WeakPolarHBondContact O-CG2 3.49Å; L280-T304 HydrophobicContact CB-CG2 4.33Å; L280-T304 VanDerWaalsContact O-CB 3.22Å; L280-T304 WeakPolarHBondContact O-CB 3.23Å; L280-T304 WeakPolarHBondContact O-CG2 3.35Å; L280-T304 PolarHBondContact O-OG1 3.34Å; T281-T304 PolarHBondContact O-OG1 2.85Å; S282-T304 VanDerWaalsContact C-CG2 3.41Å; T283-T304 HydrophobicContact CG2-CG2 4.14Å; T304-A306 PolarHBondContact O-N 3.36Å; T304-Q307 PolarHBondContact O-N 3.05Å; T304-Q307 WeakPolarHBondContact OG1-CG 3.47Å; T304-Q307 PolarHBondContact OG1-N 2.91Å; T304-Q307 PolarHBondContact OG1-OE1 3.1Å; T304-T308 WeakPolarHBondContact O-CB 3.28Å; T304-T308 PolarHBondContact O-N 2.92Å; T304-T308 PolarHBondContact O-OG1 2.82Å
305Q95Very high87Confident14 Ų1461 Ų617%0.06533%0.33CS..Hα-helixtrans-59-38.5173.5-174.6176.347.700111.5F277 T308 R309F277-Q305 HydrophobicContact CD1-CB 4.16Å; F277-Q305 HydrophobicContact CE1-CB 3.86Å; F277-Q305 HydrophobicContact CE1-CG 4.31Å; F277-Q305 HydrophobicContact CE2-CB 4.48Å; F277-Q305 HydrophobicContact CZ-CB 4.04Å; F277-Q305 VanDerWaalsContact O-CB 3.26Å; F277-Q305 WeakPolarHBondContact O-CB 3.38Å; F277-Q305 PolarHBondContact O-N 3.4Å; Q305-T308 PolarHBondContact O-N 3.48Å; Q305-R309 VanDerWaalsContact CD-NH2 3.31Å; Q305-R309 WeakPolarHBondContact O-CG 3.24Å; Q305-R309 PolarHBondContact O-N 3.27Å
306A93.6Very high88.6Confident35 Ų3566.1 Ų66.129%0.28934%0.344SS..Hα-helixtrans-60.5-47.1176.700000111.6T304 R309 Q310T304-A306 PolarHBondContact O-N 3.36Å; A306-R309 PolarHBondContact O-N 2.92Å; A306-Q310 WeakPolarHBondContact O-CG 3.5Å; A306-Q310 PolarHBondContact O-N 3.47Å
307Q94.8Very high90Very high56 Ų5667.7 Ų67.726%0.26235%0.345SS..Hα-helixtrans-66.5-37175.6-70.5174.3-48.800112.4R303 T304 Q310 A311R303-Q307 HydrophobicContact CB-CB 3.88Å; R303-Q307 HydrophobicContact CG-CB 4.32Å; T304-Q307 PolarHBondContact O-N 3.05Å; T304-Q307 WeakPolarHBondContact OG1-CG 3.47Å; T304-Q307 PolarHBondContact OG1-N 2.91Å; T304-Q307 PolarHBondContact OG1-OE1 3.1Å; Q307-Q310 PolarHBondContact O-N 3.31Å; Q307-A311 WeakPolarHBondContact O-CB 3.48Å; Q307-A311 PolarHBondContact O-N 3.31Å
308T94.9Very high90.8Very high0 Ų065.1 Ų65.10%035%0.345CS..Hα-helixtrans-61.9-47.4176.9-55.70000110D40 Y41 T304 Q305 A311 S312D40-T308 HydrophobicContact CB-CG2 4.12Å; D40-T308 WeakPolarHBondContact CB-OG1 3.34Å; D40-T308 PolarHBondContact OD2-OG1 3.14Å; Y41-T308 HydrophobicContact CD2-CG2 4.43Å; Y41-T308 HydrophobicContact CE2-CG2 3.83Å; T304-T308 WeakPolarHBondContact O-CB 3.28Å; T304-T308 PolarHBondContact O-N 2.92Å; T304-T308 PolarHBondContact O-OG1 2.82Å; Q305-T308 PolarHBondContact O-N 3.48Å; T308-A311 PolarHBondContact O-N 3.42Å; T308-S312 WeakPolarHBondContact O-CB 3.34Å; T308-S312 PolarHBondContact O-N 3.37Å; T308-S312 PolarHBondContact O-OG 3.22Å
309R94Very high90.8Very high91 Ų9167.6 Ų67.634%0.34337%0.369SS..Hα-helixtrans-63-43.2176.2-72.5-175.9-172.1161.69.6112.6Q305 A306 A311 S312 A313Q305-R309 VanDerWaalsContact CD-NH2 3.31Å; Q305-R309 WeakPolarHBondContact O-CG 3.24Å; Q305-R309 PolarHBondContact O-N 3.27Å; A306-R309 PolarHBondContact O-N 2.92Å; R309-A311 VanDerWaalsContact C-N 3.3Å; R309-A311 PolarHBondContact O-N 2.79Å; R309-S312 PolarHBondContact O-N 2.81Å; R309-A313 WeakPolarHBondContact O-CB 3.42Å; R309-A313 PolarHBondContact O-N 3.5Å
310Q93.8Very high91Very high134 Ų13460.5 Ų60.563%0.62634%0.344SS*.Hα-helixtrans-58.7-43.6175.1-75174.3-12.900111.7A306 Q307 L314A306-Q310 WeakPolarHBondContact O-CG 3.5Å; A306-Q310 PolarHBondContact O-N 3.47Å; Q307-Q310 PolarHBondContact O-N 3.31Å; Q310-L314 WeakPolarHBondContact O-CG 2.85Å
311A93.7Very high90.8Very high29 Ų2968.1 Ų68.124%0.2438%0.38CS..Hα-helixtrans-69.2-35.3176.300000112.8Q307 T308 R309 L314Q307-A311 WeakPolarHBondContact O-CB 3.48Å; Q307-A311 PolarHBondContact O-N 3.31Å; T308-A311 PolarHBondContact O-N 3.42Å; R309-A311 VanDerWaalsContact C-N 3.3Å; R309-A311 PolarHBondContact O-N 2.79Å; A311-L314 PolarHBondContact O-N 3.37Å
312S94.1Very high90.9Very high4 Ų466.3 Ų66.33%0.02836%0.363CS..Hα-helixtrans-70.2-34.8179.5-50.10000111.7T88 T308 R309 L314 I315T88-S312 WeakPolarHBondContact OG1-CB 3.47Å; T308-S312 WeakPolarHBondContact O-CB 3.34Å; T308-S312 PolarHBondContact O-N 3.37Å; T308-S312 PolarHBondContact O-OG 3.22Å; R309-S312 PolarHBondContact O-N 2.81Å; S312-L314 PolarHBondContact O-N 3.37Å; S312-L314 VanDerWaalsContact O-N 3.17Å; S312-I315 VanDerWaalsContact O-CB 3.26Å; S312-I315 WeakPolarHBondContact O-CB 3.33Å; S312-I315 VanDerWaalsContact O-CG1 3.26Å; S312-I315 WeakPolarHBondContact O-CG1 3.35Å; S312-I315 PolarHBondContact O-N 2.98Å
313A92.6Very high90.7Very high84 Ų8474 Ų7469%0.69439%0.394SS*.THydrogen-bonded Turntrans-64.5-15.6173.200000113.7R309R309-A313 WeakPolarHBondContact O-CB 3.42Å; R309-A313 PolarHBondContact O-N 3.5Å
314L93.4Very high90.4Very high144 Ų14472.3 Ų72.375%0.75439%0.388SS*.THydrogen-bonded Turntrans-963.8175.4-60.5173.3000112.8Q310 A311 S312 D316Q310-L314 WeakPolarHBondContact O-CG 2.85Å; A311-L314 PolarHBondContact O-N 3.37Å; S312-L314 PolarHBondContact O-N 3.37Å; S312-L314 VanDerWaalsContact O-N 3.17Å; L314-D316 PolarHBondContact O-N 2.94Å; L314-D316 VanDerWaalsContact O-N 3.09Å
315I92.4Very high89.3Confident41 Ų4173.8 Ų73.821%0.2140%0.397CS..  trans-69.7107176.4-65.8170.5000108.3L37 E38 E89 S312 R317L37-I315 HydrophobicContact CB-CD1 3.89Å; L37-I315 HydrophobicContact CB-CG1 4.48Å; L37-I315 HydrophobicContact CD1-CD1 4.05Å; L37-I315 HydrophobicContact CD1-CG1 3.97Å; L37-I315 HydrophobicContact CD1-CG2 3.78Å; E38-I315 HydrophobicContact CG-CD1 4.37Å; E89-I315 HydrophobicContact CG-CD1 4.13Å; S312-I315 VanDerWaalsContact O-CB 3.26Å; S312-I315 WeakPolarHBondContact O-CB 3.33Å; S312-I315 VanDerWaalsContact O-CG1 3.26Å; S312-I315 WeakPolarHBondContact O-CG1 3.35Å; S312-I315 PolarHBondContact O-N 2.98Å; I315-R317 HydrophobicContact CG2-CG 3.72Å
316D90.7Very high87.7Confident166 Ų16675.3 Ų75.389%0.88841%0.412SS*.  trans-109.380.5173.8-172.616.7000109.4L314L314-D316 PolarHBondContact O-N 2.94Å; L314-D316 VanDerWaalsContact O-N 3.09Å
317R92.4Very high85.6Confident71 Ų7175.4 Ų75.427%0.26841%0.41SS..SBendtrans-150.8153.7173.273174.9-174.2163.3-2.8110.9N35 L37 E89 I315N35-R317 VanDerWaalsContact CG-NH1 3.27Å; N35-R317 PolarHBondContact ND2-NH1 3.35Å; N35-R317 PolarHBondContact O-NH2 3.02Å; N35-R317 PolarHBondContact OD1-NH1 3.44Å; L37-R317 VanDerWaalsContact CD1-NE 3.31Å; E89-R317 IonicContact OE1-CZ 3.05Å; E89-R317 IonicContact OE1-NE 3.63Å; E89-R317 PolarHBondContact OE1-NE 2.8Å; E89-R317 IonicContact OE1-NH2 2.73Å; E89-R317 PolarHBondContact OE1-NH2 3.06Å; E89-R317 IonicContact OE2-NH2 2.63Å; E89-R317 PolarHBondContact OE2-NH2 3.39Å; E89-R317 VanDerWaalsContact OE2-NH2 3.08Å; I315-R317 HydrophobicContact CG2-CG 3.72Å
318P86.3Confident83.3Confident114 Ų11478.2 Ų78.274%0.7442%0.421SS*.PPolyproline II helixtrans-61149.5169.327.3-35.1000110.6P320P318-P320 VanDerWaalsContact O-N 3.16Å
319A82.5Confident81.2Confident72 Ų7287.4 Ų87.460%0.59546%0.456SS*.PPolyproline II helixtrans-51.6123.6175.300000109.4H321A319-H321 PolarHBondContact O-N 3.43Å
320P83Confident78.5Confident15 Ų1585.2 Ų85.210%0.09746%0.457CS..PPolyproline II helixtrans-64.4132.1-175.726.6-34.5000109.4N35 I91 P318 F322N35-P320 VanDerWaalsContact ND2-CB 3.31Å; N35-P320 WeakPolarHBondContact ND2-CB 3.35Å; I91-P320 HydrophobicContact CB-CG 4.06Å; I91-P320 HydrophobicContact CG2-CG 3.62Å; P318-P320 VanDerWaalsContact O-N 3.16Å; P320-F322 WeakPolarHBondContact O-CD1 3.41Å
321H80.8Confident75.8Confident187 Ų18783.5 Ų83.587%0.86646%0.46SS*.PPolyproline II helixtrans-76.8129.1167.7-16866.3000108.7A319A319-H321 PolarHBondContact O-N 3.43Å
322F85.8Confident73.4Confident38 Ų3893.1 Ų93.117%0.16749%0.491CS..  trans-138.2145.7176.658.6-89.6000109.8D90 I91 Y94 P320 R324D90-F322 HydrophobicContact CB-CE1 4.33Å; I91-F322 VanDerWaalsContact CA-CE1 3.49Å; I91-F322 HydrophobicContact CB-CD1 3.69Å; I91-F322 HydrophobicContact CB-CE1 3.6Å; I91-F322 HydrophobicContact CB-CG 4.48Å; I91-F322 HydrophobicContact CB-CZ 4.32Å; I91-F322 HydrophobicContact CD1-CB 4.06Å; I91-F322 HydrophobicContact CD1-CD1 3.92Å; I91-F322 HydrophobicContact CD1-CG 4.06Å; I91-F322 HydrophobicContact CG1-CD1 3.82Å; I91-F322 HydrophobicContact CG1-CE1 4.08Å; I91-F322 HydrophobicContact CG1-CG 4.12Å; Y94-F322 AromaticContact CD1-CD2 3.85Å; Y94-F322 HydrophobicContact CD1-CD2 3.85Å; Y94-F322 AromaticContact CD1-CE2 3.31Å; Y94-F322 HydrophobicContact CD1-CE2 3.31Å; Y94-F322 HydrophobicContact CD1-CZ 4.15Å; Y94-F322 HydrophobicContact CD2-CE2 4.19Å; Y94-F322 HydrophobicContact CE1-CD2 4.19Å; Y94-F322 AromaticContact CE1-CE2 3.93Å; Y94-F322 HydrophobicContact CE1-CE2 3.93Å; Y94-F322 HydrophobicContact CG-CD2 4.43Å; Y94-F322 AromaticContact CG-CE2 3.46Å; Y94-F322 HydrophobicContact CG-CE2 3.46Å; Y94-F322 VanDerWaalsContact CG-CE2 3.46Å; Y94-F322 AromaticContact CG-CZ 3.97Å; Y94-F322 HydrophobicContact CG-CZ 3.97Å; P320-F322 WeakPolarHBondContact O-CD1 3.41Å; F322-R324 HydrophobicContact CD2-CG 4.18Å; F322-R324 HydrophobicContact CE2-CG 3.87Å
323E83.5Confident70.8Confident181 Ų18197.7 Ų97.785%0.84652%0.522SS*.  trans-75.1127.8174.3-167.8175.3177.100108.9
324R86.9Confident68.3Low43 Ų43101.3 Ų101.316%0.16253%0.529CS..  trans-85.5137.5175.2-62.2178.1171.7-95.6-4.4108Y94 S126 E127 P170 D174 F322 A326Y94-R324 HydrophobicContact CE2-CB 4.37Å; Y94-R324 HydrophobicContact CE2-CG 4.22Å; Y94-R324 WeakPolarHBondContact OH-CA 3.27Å; S126-R324 WeakPolarHBondContact O-CD 3.31Å; S126-R324 PolarHBondContact OG-NH1 3.34Å; E127-R324 WeakPolarHBondContact OE2-CB 3.39Å; P170-R324 VanDerWaalsContact CB-CZ 3.41Å; P170-R324 VanDerWaalsContact CB-NE 3.34Å; D174-R324 IonicContact OD1-NH1 3.7Å; D174-R324 PolarHBondContact OD1-NH1 2.77Å; D174-R324 IonicContact OD2-CZ 3.1Å; D174-R324 VanDerWaalsContact OD2-CZ 3.23Å; D174-R324 IonicContact OD2-NH1 3.52Å; D174-R324 PolarHBondContact OD2-NH1 3.03Å; D174-R324 IonicContact OD2-NH2 3.08Å; D174-R324 PolarHBondContact OD2-NH2 3.17Å; F322-R324 HydrophobicContact CD2-CG 4.18Å; F322-R324 HydrophobicContact CE2-CG 3.87Å; R324-A326 VanDerWaalsContact C-N 3.28Å; R324-A326 PolarHBondContact O-N 2.73Å
325T72.1Confident65.7Low31 Ų31102.9 Ų102.919%0.1954%0.538CS..  trans-79.582.5-177.6-62.40000110.1D9 Y94 E127 S327D9-T325 WeakPolarHBondContact CB-OG1 3.21Å; Y94-T325 PolarHBondContact OH-N 3.21Å; E127-T325 PolarHBondContact OE2-N 3.5Å; T325-S327 PolarHBondContact O-N 2.99Å; T325-S327 VanDerWaalsContact O-N 3.11Å
326A60.6Low63.1Low46 Ų46104.4 Ų104.438%0.3856%0.564SS.*  trans-55.3119.3157.600000106.7E127 R324 K328E127-A326 PolarHBondContact OE2-N 3.37Å; R324-A326 VanDerWaalsContact C-N 3.28Å; R324-A326 PolarHBondContact O-N 2.73Å; A326-K328 PolarHBondContact O-N 2.82Å; A326-K328 VanDerWaalsContact O-N 3.09Å
327S49.7Very low60.3Low36 Ų36101.2 Ų101.225%0.25256%0.561SS.*  trans-33.9117.2-176.8178.50000111.7D143 T325 R329 A330D143-S327 VanDerWaalsContact O-CB 3.29Å; D143-S327 WeakPolarHBondContact O-CB 3.21Å; D143-S327 PolarHBondContact O-OG 3.14Å; T325-S327 PolarHBondContact O-N 2.99Å; T325-S327 VanDerWaalsContact O-N 3.11Å; S327-R329 PolarHBondContact O-N 2.64Å; S327-A330 PolarHBondContact O-N 3.25Å
328K46.6Very low57.4Low115 Ų115102.9 Ų102.950%0.559%0.59SS.*THydrogen-bonded Turntrans-62.914.5-176.2-72.1177.6-179.9159.20115.1A326A326-K328 PolarHBondContact O-N 2.82Å; A326-K328 VanDerWaalsContact O-N 3.09Å
329R50.1Low54.6Low193 Ų193102.5 Ų102.573%0.72860%0.596SS**THydrogen-bonded Turntrans-81.3-31.5163.8-105-178-168.2-151.70.3112.9S327 S331S327-R329 PolarHBondContact O-N 2.64Å; R329-S331 VanDerWaalsContact C-N 3.31Å; R329-S331 PolarHBondContact O-N 3.22Å
330A38.1Very low52.2Low45 Ų45103.8 Ų103.837%0.37261%0.607SS.*G310 helixtrans-70.5-24.4-177.100000113.5S327 R332 S333S327-A330 PolarHBondContact O-N 3.25Å; A330-R332 PolarHBondContact O-N 3.25Å; A330-R332 VanDerWaalsContact O-N 3.14Å; A330-S333 PolarHBondContact O-N 2.88Å
331S37Very low49.7Very low99 Ų99112.4 Ų112.469%0.69265%0.646SS**G310 helixtrans-73.1-2.5-179.163.90000115R329R329-S331 VanDerWaalsContact C-N 3.31Å; R329-S331 PolarHBondContact O-N 3.22Å
332R42.3Very low47.1Very low231 Ų231109.3 Ų109.387%0.87265%0.645SS**G310 helixtrans-100.3-3.5175.7-70.5-172.2171.5-169.4-3.1114.3A330A330-R332 PolarHBondContact O-N 3.25Å; A330-R332 VanDerWaalsContact O-N 3.14Å
333S39.2Very low44.7Very low99 Ų99114.1 Ų114.169%0.69268%0.678SS**SBendtrans-105.10.2-170.9-165.90000115.4A330A330-S333 PolarHBondContact O-N 2.88Å
334L40.2Very low42Very low161 Ų161113.4 Ų113.484%0.84368%0.68SS**SBendtrans-115.92.9-171.8-83.1162.1000116.3
335D40.2Very low39.3Very low177 Ų177122.4 Ų122.495%0.94771%0.714SS**SBendtrans-107.748.2171.9-94.5-14.7000111.7
336G37.4Very low37.2Very low72 Ų72126.4 Ų126.474%0.74274%0.743SS**  trans-133.129.8-171.900000114.9
337A31.3Very low36.4Very low100 Ų100129.9 Ų129.983%0.82676%0.762SS**SBendtrans-158135.8167.600000112.1
338A31.1Very low35.5Very low106 Ų106138.3 Ų138.388%0.87679%0.788SS**  trans84.679.3172.300000117.9
339A28.4Very low35.1Very low106 Ų106138.2 Ų138.288%0.87680%0.799SS**  trans-137.391.3135.700000108.5
340A31.1Very low34.1Very low99 Ų99134.4 Ų134.482%0.81880%0.797SS**  trans-69.2146.6168.100000110
341E30.3Very low33.7Very low196 Ų196137.5 Ų137.592%0.91682%0.817SS**  trans-48.2135.6178.3-67.4170.6135.300113.4
342S27.1Very low33.2Very low122 Ų122137.2 Ų137.285%0.85382%0.82SS**  trans-142.5123.4146.257.80000109.8
343T35.3Very low33.1Very low139 Ų139131.9 Ų131.985%0.85382%0.816SS**  trans-85.7122.4173.1470000109.6
344D27.2Very low32.5Very low165 Ų165131.5 Ų131.588%0.88282%0.818SS**  trans-160.2147.4142.3-149.4-2.1000113.5
345R29.8Very low32Very low232 Ų232131.9 Ų131.988%0.87582%0.819SS**  trans-96124.5-171.1-97.3175.8161.8172.6-4.2112.6
346S28Very low31.4Very low116 Ų116128.1 Ų128.181%0.81181%0.813SS**  trans59165.7139.7-111.80000121.9
347P44.3Very low31.1Very low119 Ų119134.2 Ų134.277%0.77382%0.822SS**  cis-130.9173.2-536.4-16.8000116.2
348R29.6Very low30.9Very low212 Ų212135.7 Ų135.780%0.883%0.826SS**  trans-67.5169.6176.5-148.4-168.7-168.1154.23.8114.2
349P38.4Very low30.8Very low113 Ų113139.5 Ų139.573%0.73483%0.826SS**  -138.8130.8104.831.3-15000113.5
350T30.9Very low30.8Very low113 Ų113139.9 Ų139.969%0.69382%0.817SS**  87.1111.690-47.50000110.4
351S28.9Very low30.6Very low111 Ų111141.2 Ų141.278%0.77682%0.815SS**  -158136.383.337.40000115
352A25.4Very low30.4Very low92 Ų92141.2 Ų141.276%0.7682%0.815SS**  trans-98.2-169.1164.100000108.8
353P41.2Very low30.2Very low120 Ų120139 Ų13978%0.77981%0.812SS**  cis-129.7166.811.228.9-4.4000113.9
354A26.2Very low30.5Very low90 Ų90139.2 Ų139.274%0.74482%0.815SS**  cis89.6113.232.400000116.2
355I29.8Very low30.5Very low170 Ų170135.1 Ų135.187%0.87281%0.812SS**  trans-155.298.4149.2-55.7-174.7000105.9
356A28.3Very low30.3Very low97 Ų97128.7 Ų128.780%0.80281%0.808SS**  88.5114.973.300000115
357Q31.4Very low31Very low201 Ų201128.5 Ų128.594%0.93980%0.804SS**  trans-95.5158.4159.4-78.9177.7-30.800109.5
358S27.4Very low30.2Very low131 Ų131129.6 Ų129.692%0.91680%0.802SS**  trans-144145166.442.70000112.6
359Q27.3Very low30.1Very low186 Ų186128.3 Ų128.387%0.86980%0.802SS**  trans-112.6146.9-172.9-105.7-175.6-50.300112.2
360V29.8Very low29.6Very low114 Ų114132.3 Ų132.369%0.69181%0.808SS**  trans64.9128.6136.2-169.50000122.1
361T26.2Very low29.4Very low126 Ų126133.2 Ų133.277%0.77381%0.814SS**  170139.3115.932.20000116.4
362E26.7Very low29.7Very low197 Ų197133.3 Ų133.392%0.92181%0.812SS**  trans65.7143.3148.6-66.1-167.9144.300127.1
363G23.2Very low29.7Very low76 Ų76138.2 Ų138.278%0.78482%0.816SS**  trans-86.9-147.2-17100000116.6
364P40.8Very low29Very low142 Ų142141.6 Ų141.692%0.92282%0.821SS**  cis-138.5178.417.841.4-21.8000116.9
365G26.5Very low29.1Very low79 Ų79141.4 Ų141.481%0.81482%0.82SS**  trans160.4104.7160.500000116.3
366A26.9Very low28.9Very low97 Ų97140.5 Ų140.580%0.80282%0.822SS**  trans-87.8-171.2170.500000111.1
367P41.5Very low28.7Very low112 Ų112144.9 Ų144.973%0.72782%0.823SS**  cis-141.9-171.2-6.925.71.4000115.5
368I28.5Very low28.5Very low142 Ų142140.6 Ų140.673%0.72881%0.81SS**  trans12098.5140.6-53175000117.9
369K27.4Very low28.3Very low185 Ų185142.9 Ų142.980%0.80481%0.807SS**  trans17.7132.2130.6-52.7177.4177.3178.70119.9
370K26.7Very low28.4Very low197 Ų197142 Ų14286%0.85780%0.802SS**  164.8117.4101.4-85.5178.8-173.11790112
371T28Very low28.2Very low132 Ų132146.7 Ų146.781%0.8181%0.814SS**  trans-71.1160.9144.630.50000109
372P34.9Very low28.3Very low114 Ų114152.2 Ų152.274%0.7482%0.82SS**  -154174.155.438.9-15.2000118.9
373K25.6Very low28.3Very low195 Ų195146 Ų14685%0.84881%0.809SS**  trans16143.1143.1-58.7-179.6177.5-177.80118
374E26.2Very low28.6Very low190 Ų190151.7 Ų151.789%0.88882%0.816SS**  -175.4165.668.8-160.6164.4-163.200112.4
375A27.9Very low28.1Very low87 Ų87154.1 Ų154.172%0.71982%0.815SS**  trans-66.7165.317900000114.6
376V26.9Very low28.3Very low151 Ų151156.4 Ų156.492%0.91582%0.815SS**  trans-174151.7131.5151.10000110.9
377K24Very low28.5Very low188 Ų188156.5 Ų156.582%0.81782%0.816SS**  trans-79.9160.2-168.7-115.1-176.8169.8179.10115.2
378V25.3Very low28Very low111 Ų111160.2 Ų160.267%0.67382%0.823SS**  trans74.4122.2141.1177.40000116.6
379E25.2Very low28.2Very low180 Ų180159.4 Ų159.484%0.84183%0.827SS**  -179.2161.386.9-144.3159.6-148.700112.9
380E28.2Very low28.5Very low166 Ų166155.4 Ų155.478%0.77683%0.829SS**  trans-66.5143.6-172.3-177.3-179.7168.700115.1
381K26.2Very low29Very low214 Ų214154.9 Ų154.993%0.9383%0.829SS**  trans-150.6117.9150.3-119.1-179.1-175.1-178.70113
382R27.6Very low29.4Very low242 Ų242154.5 Ų154.591%0.91383%0.829SS**  trans-61.9144.3170.6-169.7178.1-172.8-1372.3112.2
383G27.1Very low29.7Very low67 Ų67157.5 Ų157.569%0.69183%0.833SS**  trans-17992.916700000109.5
384E28.6Very low30.2Very low195 Ų195151.6 Ų151.691%0.91182%0.815SS**  81.9106105.5-103.4-179169.800114
385E31.2Very low31.2Very low193 Ų193147.1 Ų147.190%0.90280%0.801SS**  trans-63.6150.4166.9-76.2176.5130.900111.9
386P30.7Very low31.8Very low127 Ų127149 Ų14983%0.82580%0.795SS**  trans-104.6130.6147.120.4-3.3000111.1
387A30.4Very low32.4Very low99 Ų99145.2 Ų145.282%0.81878%0.779SS**PPolyproline II helixtrans-60.9144.3178.800000114.4
388E31.8Very low33.1Very low189 Ų189144.9 Ų144.988%0.88377%0.773SS**PPolyproline II helixtrans-67.2140.5164.9-73.6-174141.400111.5
389P32.2Very low33.7Very low125 Ų125144.7 Ų144.781%0.81276%0.763SS**PPolyproline II helixtrans-79.5126.1163.229.3-27.8000110.7
390A34Very low34.1Very low101 Ų101143.4 Ų143.484%0.83576%0.755SS**PPolyproline II helixtrans-56.913717700000113.5
391E37Very low34.4Very low186 Ų186143 Ų14387%0.86975%0.75SS**PPolyproline II helixtrans-71142.9169.7-66.9-170.9152.600111.2
392P36Very low34.9Very low124 Ų124142.2 Ų142.281%0.80574%0.741SS**PPolyproline II helixtrans-75.9140.717729.9-32.5000112.1
393E41.4Very low35.1Very low178 Ų178137.5 Ų137.583%0.83273%0.73SS**PPolyproline II helixtrans-57.3143.9177.9-78.6-151.5146.600113.3
394P36.8Very low35.6Very low70 Ų70145.2 Ų145.246%0.45574%0.738SS.*PPolyproline II helixtrans-73.6132.3-18029.8-33.3000112.2W398P394-W398 HydrophobicContact CB-CD2 4.39Å; P394-W398 HydrophobicContact CB-CE3 3.38Å; P394-W398 HydrophobicContact CB-CZ3 3.9Å
395T45.9Very low36.1Very low96 Ų96142.6 Ų142.659%0.58973%0.73SS**PPolyproline II helixtrans-64152.2-179.452.60000113.2A397 W398T395-A397 PolarHBondContact O-N 3.18Å; T395-W398 PolarHBondContact O-N 2.88Å
396E42.4Very low36.3Very low128 Ų128140.4 Ų140.460%0.59872%0.724SS**Hα-helixtrans-50.3-22.8179.2-73.9-66.1125.900114.7W398 K399 K400E396-W398 VanDerWaalsContact C-N 3.32Å; E396-W398 PolarHBondContact O-N 3.35Å; E396-K399 PolarHBondContact O-N 3.42Å; E396-K399 WeakPolarHBondContact OE1-CD 3.25Å; E396-K399 WeakPolarHBondContact OE1-CE 3.42Å; E396-K399 IonicContact OE1-NZ 2.78Å; E396-K399 PolarHBondContact OE1-NZ 3.39Å; E396-K400 PolarHBondContact O-N 3.04Å; E396-K400 VanDerWaalsContact O-N 3.1Å
397A39Very low36.2Very low71 Ų71137.6 Ų137.659%0.58772%0.718SS**Hα-helixtrans-67.7-27.4173.700000113.6T395T395-A397 PolarHBondContact O-N 3.18Å
398W37.8Very low36.3Very low181 Ų181141.2 Ų141.269%0.68672%0.718SS**Hα-helixtrans-81.2-28.3173.2-74.7-3.8000112.6P394 T395 E396 K401 R402P394-W398 HydrophobicContact CB-CD2 4.39Å; P394-W398 HydrophobicContact CB-CE3 3.38Å; P394-W398 HydrophobicContact CB-CZ3 3.9Å; T395-W398 PolarHBondContact O-N 2.88Å; E396-W398 VanDerWaalsContact C-N 3.32Å; E396-W398 PolarHBondContact O-N 3.35Å; W398-K401 PolarHBondContact O-N 2.93Å; W398-R402 PolarHBondContact O-N 3.29Å
399K37.6Very low36.4Very low107 Ų107137 Ų13747%0.46570%0.701SS.*Hα-helixtrans-68.2-44.1171.8-65.6-175.2-169.3162.90111.4E396 K401 R402 E403E396-K399 PolarHBondContact O-N 3.42Å; E396-K399 WeakPolarHBondContact OE1-CD 3.25Å; E396-K399 WeakPolarHBondContact OE1-CE 3.42Å; E396-K399 IonicContact OE1-NZ 2.78Å; E396-K399 PolarHBondContact OE1-NZ 3.39Å; K399-K401 PolarHBondContact O-N 2.91Å; K399-R402 WeakPolarHBondContact O-CA 3.26Å; K399-R402 WeakPolarHBondContact O-CB 3.26Å; K399-R402 PolarHBondContact O-N 3.34Å; K399-E403 PolarHBondContact O-N 2.9Å; K399-E403 VanDerWaalsContact O-N 3.11Å
400K33.8Very low36.7Very low153 Ų153137.4 Ų137.467%0.66570%0.696SS**Hα-helixtrans-62.8-24.5175.4-105.5179178.5172.80115E396E396-K400 PolarHBondContact O-N 3.04Å; E396-K400 VanDerWaalsContact O-N 3.1Å
401K35.9Very low36.9Very low157 Ų157138 Ų13868%0.68368%0.677SS**Hα-helixtrans-82.7-19175.4-153.5174.5-173.2174.30112.5W398 K399W398-K401 PolarHBondContact O-N 2.93Å; K399-K401 PolarHBondContact O-N 2.91Å
402R35Very low37Very low197 Ų197133.6 Ų133.674%0.74366%0.659SS**Hα-helixtrans-84.8-35.7176.2-158.8176.6165.3-157-7.1111.3W398 K399 R404 L405W398-R402 PolarHBondContact O-N 3.29Å; K399-R402 WeakPolarHBondContact O-CA 3.26Å; K399-R402 WeakPolarHBondContact O-CB 3.26Å; K399-R402 PolarHBondContact O-N 3.34Å; R402-R404 VanDerWaalsContact C-N 3.32Å; R402-R404 PolarHBondContact O-N 3.48Å; R402-L405 WeakPolarHBondContact O-CB 3.46Å; R402-L405 PolarHBondContact O-N 2.91Å; R402-L405 VanDerWaalsContact O-N 3.09Å
403E33.5Very low36.9Very low143 Ų143137.5 Ų137.567%0.66866%0.657SS**Hα-helixtrans-66.8-26.7173.3-83.3177.6148.600113.9K399 L405K399-E403 PolarHBondContact O-N 2.9Å; K399-E403 VanDerWaalsContact O-N 3.11Å; E403-L405 PolarHBondContact O-N 2.89Å
404R36Very low36.3Very low230 Ų230135.9 Ų135.987%0.86865%0.649SS**THydrogen-bonded Turntrans-78.1-1172.2-70-171.3-178.5-172.7-0.4114.1R402R402-R404 VanDerWaalsContact C-N 3.32Å; R402-R404 PolarHBondContact O-N 3.48Å
405L39.8Very low36Very low140 Ų140135.5 Ų135.573%0.73365%0.648SS**THydrogen-bonded Turntrans-1050.6175.9-79.7161.3000112.8R402 E403 G407R402-L405 WeakPolarHBondContact O-CB 3.46Å; R402-L405 PolarHBondContact O-N 2.91Å; R402-L405 VanDerWaalsContact O-N 3.09Å; E403-L405 PolarHBondContact O-N 2.89Å; L405-G407 VanDerWaalsContact C-N 3.26Å; L405-G407 PolarHBondContact O-N 3.47Å
406D34.8Very low35.3Very low146 Ų146134.4 Ų134.478%0.78164%0.639SS**  trans-9330.5171.5-87.8-16000112.3E408D406-E408 PolarHBondContact O-N 2.95Å
407G29.7Very low34.9Very low68 Ų68133.8 Ų133.870%0.70164%0.639SS**SBendtrans-8196.3164.200000109.2L405L405-G407 VanDerWaalsContact C-N 3.26Å; L405-G407 PolarHBondContact O-N 3.47Å
408E32.2Very low34.7Very low176 Ų176138.3 Ų138.382%0.82265%0.65SS**  trans24107.9164.6-77.5174.3152.300117.7D406 I410D406-E408 PolarHBondContact O-N 2.95Å; E408-I410 PolarHBondContact O-N 3.36Å
409N32.8Very low35Very low100 Ų100134.4 Ų134.454%0.53564%0.642SS.*  trans-57.1110.3178.7-170.59000113.3Y411 I412N409-Y411 PolarHBondContact O-N 3.05Å; N409-Y411 VanDerWaalsContact O-N 3.14Å; N409-Y411 VanDerWaalsContact OD1-CB 3.31Å; N409-Y411 WeakPolarHBondContact OD1-CB 3.3Å; N409-Y411 PolarHBondContact OD1-N 3.46Å; N409-Y411 VanDerWaalsContact OD1-N 3.15Å; N409-I412 HydrophobicContact CB-CD1 4.36Å; N409-I412 HydrophobicContact CB-CG1 4.27Å; N409-I412 PolarHBondContact O-N 2.66Å
410I39.6Very low34.9Very low134 Ų134137 Ų13769%0.68766%0.656SS**Hα-helixtrans-61-17.8173.2-65.6170.8000112.4E408 I412 R413 H414E408-I410 PolarHBondContact O-N 3.36Å; I410-I412 PolarHBondContact O-N 3.08Å; I410-R413 PolarHBondContact O-N 2.8Å; I410-H414 PolarHBondContact O-N 2.92Å
411Y38.2Very low35.1Very low112 Ų112135.4 Ų135.444%0.43965%0.654SS.*Hα-helixtrans-61.7-26.1171-91.6-107.6000112.7L197 E198 N409 S415L197-Y411 HydrophobicContact CD1-CE2 4.44Å; E198-Y411 WeakPolarHBondContact OE1-CD1 3.5Å; N409-Y411 PolarHBondContact O-N 3.05Å; N409-Y411 VanDerWaalsContact O-N 3.14Å; N409-Y411 VanDerWaalsContact OD1-CB 3.31Å; N409-Y411 WeakPolarHBondContact OD1-CB 3.3Å; N409-Y411 PolarHBondContact OD1-N 3.46Å; N409-Y411 VanDerWaalsContact OD1-N 3.15Å; Y411-S415 WeakPolarHBondContact O-CB 3.32Å; Y411-S415 PolarHBondContact O-N 3.21Å
412I38.7Very low35.5Very low95 Ų95135 Ų13549%0.48766%0.659SS.*Hα-helixtrans-75.4-34.8-179.8-59.8-176.4000110.7N409 I410 N416N409-I412 HydrophobicContact CB-CD1 4.36Å; N409-I412 HydrophobicContact CB-CG1 4.27Å; N409-I412 PolarHBondContact O-N 2.66Å; I410-I412 PolarHBondContact O-N 3.08Å; I412-N416 VanDerWaalsContact CG2-ND2 3.31Å; I412-N416 WeakPolarHBondContact CG2-ND2 3.35Å; I412-N416 WeakPolarHBondContact O-CB 3.42Å; I412-N416 PolarHBondContact O-N 3.17Å
413R33.6Very low36.1Very low205 Ų205133.4 Ų133.477%0.77467%0.665SS**Hα-helixtrans-72.2-42178.4-74.8-163.1-174.1178.51.8113I410 L417I410-R413 PolarHBondContact O-N 2.8Å; R413-L417 WeakPolarHBondContact O-CB 3.44Å; R413-L417 PolarHBondContact O-N 3.18Å; R413-L417 VanDerWaalsContact O-N 3.13Å
414H30.3Very low36.9Very low145 Ų145132.9 Ų132.967%0.67166%0.661SS**Hα-helixtrans-79-22.8-177.6-138.2-44.1000113.5I410I410-H414 PolarHBondContact O-N 2.92Å
415S29.7Very low37.9Very low62 Ų62124.5 Ų124.543%0.43464%0.638SS.*Hα-helixtrans-86.5-35.3173.5-170.60000112.8Y411 M418Y411-S415 WeakPolarHBondContact O-CB 3.32Å; Y411-S415 PolarHBondContact O-N 3.21Å; S415-M418 PolarHBondContact O-N 2.88Å
416N31.1Very low38.1Very low73 Ų73124.2 Ų124.239%0.3963%0.632SS.*Hα-helixtrans-77.8-24177.4-70.75.7000112.7I412 M418 L419 E420I412-N416 VanDerWaalsContact CG2-ND2 3.31Å; I412-N416 WeakPolarHBondContact CG2-ND2 3.35Å; I412-N416 WeakPolarHBondContact O-CB 3.42Å; I412-N416 PolarHBondContact O-N 3.17Å; N416-M418 PolarHBondContact O-N 3.45Å; N416-L419 PolarHBondContact O-N 3.46Å; N416-L419 VanDerWaalsContact O-N 3.08Å; N416-E420 PolarHBondContact O-N 3.4Å
417L33.2Very low38.8Very low114 Ų114124.9 Ų124.960%0.59763%0.631SS**THydrogen-bonded Turntrans-63.7-5.5172-13977.1000114.1R413 I612R413-L417 WeakPolarHBondContact O-CB 3.44Å; R413-L417 PolarHBondContact O-N 3.18Å; R413-L417 VanDerWaalsContact O-N 3.13Å; L417-I612 HydrophobicContact CD1-CD1 3.79Å; L417-I612 HydrophobicContact CD2-CD1 4.42Å
418M35.3Very low39.7Very low166 Ų166126.7 Ų126.782%0.81862%0.621SS**THydrogen-bonded Turntrans-126.613.4176-63.1-68.7-96.200112.6S415 N416S415-M418 PolarHBondContact O-N 2.88Å; N416-M418 PolarHBondContact O-N 3.45Å
419L43.3Very low40.5Very low99 Ų99122.6 Ų122.652%0.51860%0.604SS.*THydrogen-bonded Turntrans-129.40.3-178.2-88.2163.6000115.4N416 D421N416-L419 PolarHBondContact O-N 3.46Å; N416-L419 VanDerWaalsContact O-N 3.08Å; L419-D421 VanDerWaalsContact C-N 3.34Å; L419-D421 PolarHBondContact O-N 2.89Å
420E37Very low41.3Very low163 Ų163124.1 Ų124.176%0.76261%0.606SS**  trans-9766.5166.1-73.2172.8-170.300110N416N416-E420 PolarHBondContact O-N 3.4Å
421D37.8Very low41.9Very low118 Ų118125.6 Ų125.663%0.63161%0.607SS**  trans-147.243.9157.8-109.7-7.8000107.7L419 D423L419-D421 VanDerWaalsContact C-N 3.34Å; L419-D421 PolarHBondContact O-N 2.89Å; D421-D423 PolarHBondContact O-N 3.18Å
422L43.9Very low42.2Very low148 Ų148124.7 Ų124.778%0.77561%0.607SS**THydrogen-bonded Turntrans-81.363169.3-83.7164.7000109.3
423D46.9Very low42.6Very low165 Ų165126.4 Ų126.488%0.88261%0.612SS**THydrogen-bonded Turntrans-15214.6153.3-95.6-20.9000113D421D421-D423 PolarHBondContact O-N 3.18Å
424K51.4Low43.2Very low131 Ų131118.9 Ų118.957%0.5759%0.594SS**SBendtrans-109.3123.1166.4-70.7173.6-174.5160.80109.4I429K424-I429 HydrophobicContact CB-CG1 4.39Å
425S56.7Low44.2Very low55 Ų55114.2 Ų114.239%0.38558%0.578SS.*  trans-60.3146.4-175.864.30000110.9E427 E428 I429S425-E427 PolarHBondContact O-N 3.42Å; S425-E428 PolarHBondContact N-OE2 2.86Å; S425-E428 PolarHBondContact O-N 3.19Å; S425-E428 VanDerWaalsContact OG-CD 3.31Å; S425-E428 WeakPolarHBondContact OG-CG 3.23Å; S425-E428 PolarHBondContact OG-N 3.04Å; S425-E428 PolarHBondContact OG-OE2 3.36Å; S425-I429 PolarHBondContact O-N 3.28Å
426Q44.4Very low45Very low133 Ų133113.9 Ų113.962%0.62157%0.571SS**Hα-helixtrans-53.8-19.3173.5-98.6-94-39.500113K430Q426-K430 WeakPolarHBondContact O-CB 3.38Å; Q426-K430 VanDerWaalsContact O-CD 3.32Å; Q426-K430 WeakPolarHBondContact O-CD 3.48Å; Q426-K430 VanDerWaalsContact O-CG 3.22Å; Q426-K430 WeakPolarHBondContact O-CG 3.42Å; Q426-K430 PolarHBondContact O-N 3.07Å
427E48.6Very low45.8Very low160 Ų160113.3 Ų113.375%0.74857%0.572SS**Hα-helixtrans-78.7-40.3173.4-71.1-175.2162.700112.4S425 K430 K431S425-E427 PolarHBondContact O-N 3.42Å; E427-K430 PolarHBondContact O-N 2.69Å; E427-K431 WeakPolarHBondContact O-CB 3.46Å; E427-K431 PolarHBondContact O-N 3.47Å
428E48.4Very low46.7Very low107 Ų107113.9 Ų113.950%0.557%0.572SS.*Hα-helixtrans-66.7-41.9177.3-76.4161.7146.600112.4S425 K430 K431 H432S425-E428 PolarHBondContact N-OE2 2.86Å; S425-E428 PolarHBondContact O-N 3.19Å; S425-E428 VanDerWaalsContact OG-CD 3.31Å; S425-E428 WeakPolarHBondContact OG-CG 3.23Å; S425-E428 PolarHBondContact OG-N 3.04Å; S425-E428 PolarHBondContact OG-OE2 3.36Å; E428-K430 VanDerWaalsContact C-N 3.34Å; E428-K430 PolarHBondContact O-N 2.8Å; E428-K431 WeakPolarHBondContact O-CB 3.22Å; E428-K431 PolarHBondContact O-N 2.7Å; E428-H432 WeakPolarHBondContact O-CB 3.5Å; E428-H432 PolarHBondContact O-N 3.43Å
429I49.6Very low47.5Very low90 Ų90109.5 Ų109.546%0.46255%0.551SS.*Hα-helixtrans-64.3-40.1176.9-62.7172.3000110.8K424 S425 H432 H433K424-I429 HydrophobicContact CB-CG1 4.39Å; S425-I429 PolarHBondContact O-N 3.28Å; I429-H432 PolarHBondContact O-N 2.89Å; I429-H433 WeakPolarHBondContact O-CB 3.14Å; I429-H433 PolarHBondContact O-N 2.84Å
430K48.9Very low47.9Very low131 Ų131111 Ų11157%0.5755%0.554SS**Hα-helixtrans-67.5-37.4174.4-74.9173.5-170.21620111.7Q426 E427 E428 A434Q426-K430 WeakPolarHBondContact O-CB 3.38Å; Q426-K430 VanDerWaalsContact O-CD 3.32Å; Q426-K430 WeakPolarHBondContact O-CD 3.48Å; Q426-K430 VanDerWaalsContact O-CG 3.22Å; Q426-K430 WeakPolarHBondContact O-CG 3.42Å; Q426-K430 PolarHBondContact O-N 3.07Å; E427-K430 PolarHBondContact O-N 2.69Å; E428-K430 VanDerWaalsContact C-N 3.34Å; E428-K430 PolarHBondContact O-N 2.8Å; K430-A434 WeakPolarHBondContact O-CB 3.47Å; K430-A434 PolarHBondContact O-N 3.17Å
431K52.7Low48.9Very low166 Ų166109.1 Ų109.172%0.72254%0.543SS*.Hα-helixtrans-65.6-40.7175.3-137.4174.8-176.5-179.30111.6E427 E428 S435E427-K431 WeakPolarHBondContact O-CB 3.46Å; E427-K431 PolarHBondContact O-N 3.47Å; E428-K431 WeakPolarHBondContact O-CB 3.22Å; E428-K431 PolarHBondContact O-N 2.7Å; K431-S435 VanDerWaalsContact O-CB 3.26Å; K431-S435 WeakPolarHBondContact O-CB 3.36Å; K431-S435 PolarHBondContact O-N 3.03Å
432H44.9Very low49.5Very low93 Ų93108 Ų10843%0.43154%0.537SS..Hα-helixtrans-68.7-42178-143.2-67.2000111.9E428 I429 S435 I436 D582E428-H432 WeakPolarHBondContact O-CB 3.5Å; E428-H432 PolarHBondContact O-N 3.43Å; I429-H432 PolarHBondContact O-N 2.89Å; H432-S435 WeakPolarHBondContact O-CB 3.39Å; H432-S435 PolarHBondContact O-N 3.3Å; H432-I436 VanDerWaalsContact O-CG1 3.26Å; H432-I436 WeakPolarHBondContact O-CG1 3.1Å; H432-I436 PolarHBondContact O-N 2.72Å; H432-D582 IonicContact CE1-OD1 3.31Å; H432-D582 IonicContact CE1-OD2 2.64Å; H432-D582 PolarHBondContact CE1-OD2 3.18Å; H432-D582 IonicContact ND1-OD2 2.69Å; H432-D582 IonicContact NE2-OD2 2.78Å
433H45.9Very low49.9Very low130 Ų130104.1 Ų104.160%0.60251%0.514SS*.Hα-helixtrans-71.4-33.9177.5-144.884.3000112.6I429 S437I429-H433 WeakPolarHBondContact O-CB 3.14Å; I429-H433 PolarHBondContact O-N 2.84Å; H433-S437 WeakPolarHBondContact O-CB 3.49Å; H433-S437 PolarHBondContact O-N 2.75Å; H433-S437 VanDerWaalsContact O-N 3.08Å; H433-S437 PolarHBondContact O-OG 2.75Å
434A47.6Very low50.2Low48 Ų48103.5 Ų103.540%0.39751%0.508SS..Hα-helixtrans-66.4-44.2170.100000111.1K430 I436 S437 E438K430-A434 WeakPolarHBondContact O-CB 3.47Å; K430-A434 PolarHBondContact O-N 3.17Å; A434-I436 PolarHBondContact O-N 2.74Å; A434-S437 PolarHBondContact O-N 2.8Å; A434-E438 WeakPolarHBondContact O-CB 3.32Å; A434-E438 WeakPolarHBondContact O-CG 3.45Å; A434-E438 PolarHBondContact O-N 2.83Å
435S50.8Low49.9Very low47 Ų47103.2 Ų103.233%0.32951%0.508SS..Hα-helixtrans-58.3-47.7174.5-175.80000112K431 H432 S437 E438 L439K431-S435 VanDerWaalsContact O-CB 3.26Å; K431-S435 WeakPolarHBondContact O-CB 3.36Å; K431-S435 PolarHBondContact O-N 3.03Å; H432-S435 WeakPolarHBondContact O-CB 3.39Å; H432-S435 PolarHBondContact O-N 3.3Å; S435-S437 VanDerWaalsContact C-N 3.31Å; S435-S437 PolarHBondContact O-N 3.45Å; S435-E438 PolarHBondContact O-N 2.96Å; S435-L439 VanDerWaalsContact O-CB 3.25Å; S435-L439 WeakPolarHBondContact O-CB 3.21Å; S435-L439 WeakPolarHBondContact O-CD1 3.18Å; S435-L439 VanDerWaalsContact O-CG 3.31Å; S435-L439 WeakPolarHBondContact O-CG 3.31Å; S435-L439 PolarHBondContact O-N 3.46Å
436I45.4Very low49.1Very low55 Ų55103.7 Ų103.728%0.28251%0.512SS..Hα-helixtrans-63.4-36.3177.5-69.4166.4000111.8H432 A434 K440H432-I436 VanDerWaalsContact O-CG1 3.26Å; H432-I436 WeakPolarHBondContact O-CG1 3.1Å; H432-I436 PolarHBondContact O-N 2.72Å; A434-I436 PolarHBondContact O-N 2.74Å; I436-K440 HydrophobicContact CG2-CD 4.41Å; I436-K440 WeakPolarHBondContact O-CB 3.24Å; I436-K440 VanDerWaalsContact O-CG 3.32Å; I436-K440 WeakPolarHBondContact O-CG 3.22Å; I436-K440 PolarHBondContact O-N 3.35Å
437S49.6Very low49Very low60 Ų60102.5 Ų102.542%0.4251%0.513SS..Hα-helixtrans-76.4-38179.6-59.30000112.1H433 A434 S435 K440 K441H433-S437 WeakPolarHBondContact O-CB 3.49Å; H433-S437 PolarHBondContact O-N 2.75Å; H433-S437 VanDerWaalsContact O-N 3.08Å; H433-S437 PolarHBondContact O-OG 2.75Å; A434-S437 PolarHBondContact O-N 2.8Å; S435-S437 VanDerWaalsContact C-N 3.31Å; S435-S437 PolarHBondContact O-N 3.45Å; S437-K440 PolarHBondContact O-N 3.08Å; S437-K441 WeakPolarHBondContact O-CB 3.23Å; S437-K441 PolarHBondContact O-N 3.5Å
438E51.7Low48.7Very low127 Ų12799.5 Ų99.559%0.59351%0.508SS*.Hα-helixtrans-67.8-36.6171.5-75.3-170.717400111.7A434 S435 K441 N442A434-E438 WeakPolarHBondContact O-CB 3.32Å; A434-E438 WeakPolarHBondContact O-CG 3.45Å; A434-E438 PolarHBondContact O-N 2.83Å; S435-E438 PolarHBondContact O-N 2.96Å; E438-K441 PolarHBondContact O-N 3Å; E438-N442 VanDerWaalsContact O-CB 3.24Å; E438-N442 WeakPolarHBondContact O-CB 3.47Å; E438-N442 VanDerWaalsContact O-CG 3.3Å; E438-N442 PolarHBondContact O-N 2.81Å; E438-N442 PolarHBondContact O-ND2 3.1Å
439L52.3Low48.1Very low73 Ų73102.8 Ų102.838%0.38252%0.523SS..Hα-helixtrans-64.7-45.3172.5-83.5159000111.4S435 K441 F443 V586S435-L439 VanDerWaalsContact O-CB 3.25Å; S435-L439 WeakPolarHBondContact O-CB 3.21Å; S435-L439 WeakPolarHBondContact O-CD1 3.18Å; S435-L439 VanDerWaalsContact O-CG 3.31Å; S435-L439 WeakPolarHBondContact O-CG 3.31Å; S435-L439 PolarHBondContact O-N 3.46Å; L439-K441 VanDerWaalsContact C-N 3.31Å; L439-K441 PolarHBondContact O-N 3.48Å; L439-F443 WeakPolarHBondContact O-CB 3.32Å; L439-F443 PolarHBondContact O-N 3.2Å; L439-V586 HydrophobicContact CD2-CG2 4.1Å
440K50.9Low47.6Very low132 Ų132104.4 Ų104.457%0.57454%0.539SS*.Hα-helixtrans-61-40.6173.3-78.5174.7-179.7175.50112I436 S437 M444I436-K440 HydrophobicContact CG2-CD 4.41Å; I436-K440 WeakPolarHBondContact O-CB 3.24Å; I436-K440 VanDerWaalsContact O-CG 3.32Å; I436-K440 WeakPolarHBondContact O-CG 3.22Å; I436-K440 PolarHBondContact O-N 3.35Å; S437-K440 PolarHBondContact O-N 3.08Å; K440-M444 WeakPolarHBondContact O-CB 3.46Å; K440-M444 VanDerWaalsContact O-CG 3.31Å; K440-M444 WeakPolarHBondContact O-CG 3.41Å; K440-M444 PolarHBondContact O-N 3.27Å; K440-M444 VanDerWaalsContact O-N 3.08Å
441K58.2Low47.4Very low123 Ų123109.2 Ų109.254%0.53555%0.554SS.*Hα-helixtrans-67.6-52.5176.9-177.4-175.9156.1170.10111.5S437 E438 L439 F443 M444 E445S437-K441 WeakPolarHBondContact O-CB 3.23Å; S437-K441 PolarHBondContact O-N 3.5Å; E438-K441 PolarHBondContact O-N 3Å; L439-K441 VanDerWaalsContact C-N 3.31Å; L439-K441 PolarHBondContact O-N 3.48Å; K441-F443 PolarHBondContact O-N 2.99Å; K441-M444 CarbonylContact O-C 3.54Å; K441-M444 PolarHBondContact O-N 3.15Å; K441-E445 WeakPolarHBondContact CE-OE2 3.44Å; K441-E445 IonicContact NZ-OE2 3.52Å; K441-E445 VanDerWaalsContact O-CB 3.23Å; K441-E445 WeakPolarHBondContact O-CB 3.31Å; K441-E445 PolarHBondContact O-N 3.2Å
442N51.4Low46.7Very low95 Ų95105.7 Ų105.751%0.50855%0.548SS..Hα-helixtrans-60.3-34177-76.5-18.9000112.1E438 E445 S446E438-N442 VanDerWaalsContact O-CB 3.24Å; E438-N442 WeakPolarHBondContact O-CB 3.47Å; E438-N442 VanDerWaalsContact O-CG 3.3Å; E438-N442 PolarHBondContact O-N 2.81Å; E438-N442 PolarHBondContact O-ND2 3.1Å; N442-E445 PolarHBondContact O-N 3.09Å; N442-S446 VanDerWaalsContact O-CB 3.24Å; N442-S446 WeakPolarHBondContact O-CB 3.45Å; N442-S446 PolarHBondContact O-N 3.13Å; N442-S446 PolarHBondContact O-OG 2.78Å
443F52.2Low46.8Very low66 Ų66103.7 Ų103.729%0.28954%0.544SS..Hα-helixtrans-66.7-38.5173.4179.9-100.1000112.4L439 K441 I589 V601 V604L439-F443 WeakPolarHBondContact O-CB 3.32Å; L439-F443 PolarHBondContact O-N 3.2Å; K441-F443 PolarHBondContact O-N 2.99Å; F443-I589 HydrophobicContact CD2-CG2 3.96Å; F443-I589 HydrophobicContact CE2-CG2 3.34Å; F443-I589 HydrophobicContact CZ-CG2 4.1Å; F443-V601 HydrophobicContact CE1-CG1 4.29Å; F443-V601 HydrophobicContact CZ-CB 4.44Å; F443-V601 HydrophobicContact CZ-CG1 4.32Å; F443-V601 HydrophobicContact CZ-CG2 4.26Å; F443-V604 HydrophobicContact CE1-CG2 4.07Å; F443-V604 HydrophobicContact CZ-CG2 4.5Å
444M51.5Low46.5Very low151 Ų151105.1 Ų105.174%0.74455%0.551SS**Hα-helixtrans-78.6-24.4175.2-71.8-176.166.100113.5K440 K441K440-M444 WeakPolarHBondContact O-CB 3.46Å; K440-M444 VanDerWaalsContact O-CG 3.31Å; K440-M444 WeakPolarHBondContact O-CG 3.41Å; K440-M444 PolarHBondContact O-N 3.27Å; K440-M444 VanDerWaalsContact O-N 3.08Å; K441-M444 CarbonylContact O-C 3.54Å; K441-M444 PolarHBondContact O-N 3.15Å
445E45.9Very low46.3Very low125 Ų125111.9 Ų111.958%0.58457%0.567SS**Hα-helixtrans-94.6-16.7-175.6-159.4164.4-155.700112.6K441 N442 V447K441-E445 WeakPolarHBondContact CE-OE2 3.44Å; K441-E445 IonicContact NZ-OE2 3.52Å; K441-E445 VanDerWaalsContact O-CB 3.23Å; K441-E445 WeakPolarHBondContact O-CB 3.31Å; K441-E445 PolarHBondContact O-N 3.2Å; N442-E445 PolarHBondContact O-N 3.09Å; E445-V447 VanDerWaalsContact C-N 3.34Å; E445-V447 PolarHBondContact O-N 2.8Å
446S40.3Very low46.1Very low65 Ų65113.4 Ų113.446%0.45557%0.571SS.*  trans-92.947.3175.860.90000114N442 P448 K593N442-S446 VanDerWaalsContact O-CB 3.24Å; N442-S446 WeakPolarHBondContact O-CB 3.45Å; N442-S446 PolarHBondContact O-N 3.13Å; N442-S446 PolarHBondContact O-OG 2.78Å; S446-P448 WeakPolarHBondContact O-CD 3.22Å; S446-K593 PolarHBondContact O-NZ 3.28Å
447V42.1Very low46.2Very low108 Ų108117.8 Ų117.866%0.65559%0.588SS**  trans-79.6115.8164.6-177.50000107E445 E449E445-V447 VanDerWaalsContact C-N 3.34Å; E445-V447 PolarHBondContact O-N 2.8Å; V447-E449 PolarHBondContact O-N 3.46Å
448P41.7Very low46.2Very low97 Ų97124 Ų12463%0.6360%0.603SS**  trans-60.4141.5171.2-1427.6000108.9S446S446-P448 WeakPolarHBondContact O-CD 3.22Å
449E37.5Very low45.9Very low177 Ų177124.4 Ų124.483%0.82761%0.608SS**  trans-45132.8170.3-97176.8159.300110V447 R451V447-E449 PolarHBondContact O-N 3.46Å; E449-R451 PolarHBondContact O-N 3.44Å
450P38.2Very low45.6Very low123 Ų123125.9 Ų125.980%0.79962%0.624SS**  trans-56.8109.1-179.7-19.229000108.9
451R45.5Very low45.2Very low232 Ų232124.4 Ų124.488%0.87563%0.626SS**PPolyproline II helixtrans-68.3129.1165.7-71-174.9-170.4179.74.5106.3E449 S453E449-R451 PolarHBondContact O-N 3.44Å; R451-S453 PolarHBondContact O-N 3.07Å
452P37.5Very low44.4Very low93 Ų93127.1 Ų127.160%0.60464%0.641SS**PPolyproline II helixtrans-58.2127.7-179.316.1-24.1000109.2D456P452-D456 HydrophobicContact CB-CB 4.23Å
453S47.1Very low43.7Very low50 Ų50126.9 Ų126.935%0.3565%0.647SS.*PPolyproline II helixtrans-65.7156-179.973.70000109.3R451 W455 D456R451-S453 PolarHBondContact O-N 3.07Å; S453-W455 PolarHBondContact O-N 2.71Å; S453-W455 WeakPolarHBondContact OG-CB 3.45Å; S453-W455 PolarHBondContact OG-N 3.04Å; S453-D456 PolarHBondContact N-OD2 3.27Å; S453-D456 WeakPolarHBondContact O-CB 3.23Å; S453-D456 PolarHBondContact O-N 3.24Å; S453-D456 PolarHBondContact OG-N 2.86Å; S453-D456 PolarHBondContact OG-OD2 3.05Å
454E40.2Very low43Very low160 Ų160129.5 Ų129.575%0.74867%0.67SS**Hα-helixtrans-60.3-13.3174.2-63.5-168.7151.300112.9
455W42.9Very low42.3Very low191 Ų191131.4 Ų131.472%0.72368%0.675SS**Hα-helixtrans-74.2-34.1172.1-61.385.2000112.8S453 K457 R458 L459S453-W455 PolarHBondContact O-N 2.71Å; S453-W455 WeakPolarHBondContact OG-CB 3.45Å; S453-W455 PolarHBondContact OG-N 3.04Å; W455-K457 VanDerWaalsContact C-N 3.31Å; W455-K457 PolarHBondContact O-N 3.38Å; W455-R458 PolarHBondContact O-N 3.19Å; W455-R458 VanDerWaalsContact O-N 3.16Å; W455-L459 PolarHBondContact O-N 2.99Å; W455-L459 VanDerWaalsContact O-N 3.16Å
456D46.1Very low41.9Very low79 Ų79137 Ų13742%0.42269%0.691SS.*Hα-helixtrans-70-29.5177.3-63.2-56.8000112.2P452 S453 R458 S460P452-D456 HydrophobicContact CB-CB 4.23Å; S453-D456 PolarHBondContact N-OD2 3.27Å; S453-D456 WeakPolarHBondContact O-CB 3.23Å; S453-D456 PolarHBondContact O-N 3.24Å; S453-D456 PolarHBondContact OG-N 2.86Å; S453-D456 PolarHBondContact OG-OD2 3.05Å; D456-R458 VanDerWaalsContact C-N 3.33Å; D456-S460 WeakPolarHBondContact O-CB 3.36Å; D456-S460 PolarHBondContact O-N 2.63Å; D456-S460 PolarHBondContact O-OG 3.3Å
457K46.7Very low41.6Very low147 Ų147140.7 Ų140.764%0.63971%0.711SS**Hα-helixtrans-71.6-26.2172.7-72.2179.5-179.1172.10112.8W455 T461W455-K457 VanDerWaalsContact C-N 3.31Å; W455-K457 PolarHBondContact O-N 3.38Å; K457-T461 PolarHBondContact O-OG1 3.25Å
458R51.4Low41Very low190 Ų190144.1 Ų144.172%0.71772%0.724SS**Hα-helixtrans-84.4-33.5179.5-75.1178.8152.3-166.5-5113.1W455 D456 S460 T461W455-R458 PolarHBondContact O-N 3.19Å; W455-R458 VanDerWaalsContact O-N 3.16Å; D456-R458 VanDerWaalsContact C-N 3.33Å; R458-S460 VanDerWaalsContact C-N 3.33Å; R458-T461 PolarHBondContact O-OG1 3.38Å
459L43.5Very low40.6Very low136 Ų136147 Ų14771%0.71273%0.734SS**Hα-helixtrans-75.9-21.5174.9-75.8159.4000113.1W455 T461W455-L459 PolarHBondContact O-N 2.99Å; W455-L459 VanDerWaalsContact O-N 3.16Å; L459-T461 VanDerWaalsContact C-N 3.33Å; L459-T461 PolarHBondContact O-N 2.97Å
460S47.6Very low40.6Very low103 Ų103145.6 Ų145.672%0.7273%0.731SS**THydrogen-bonded Turntrans-80.1-7.2178.6-61.80000114.7D456 R458D456-S460 WeakPolarHBondContact O-CB 3.36Å; D456-S460 PolarHBondContact O-N 2.63Å; D456-S460 PolarHBondContact O-OG 3.3Å; R458-S460 VanDerWaalsContact C-N 3.33Å
461T41.1Very low40.7Very low101 Ų101146.9 Ų146.962%0.6273%0.731SS**SBendtrans-105.7-8.6-176.237.90000115K457 R458 L459K457-T461 PolarHBondContact O-OG1 3.25Å; R458-T461 PolarHBondContact O-OG1 3.38Å; L459-T461 VanDerWaalsContact C-N 3.33Å; L459-T461 PolarHBondContact O-N 2.97Å
462H43.2Very low40.5Very low180 Ų180139.8 Ų139.883%0.83373%0.73SS**  trans-143.580.3175-81.9-78.5000112.6
463S35.3Very low40.2Very low91 Ų91144.4 Ų144.464%0.63674%0.743SS**  trans-123.9131.4160.8-179.30000109.4F465S463-F465 VanDerWaalsContact C-N 3.32Å; S463-F465 PolarHBondContact O-N 3.46Å
464P38.4Very low39.8Very low121 Ų121148.5 Ų148.579%0.78677%0.766SS**SBendtrans-84.814.7-167.534.8-36.8000115.3
465F35.7Very low39.6Very low190 Ų190146.7 Ų146.783%0.83377%0.768SS**  trans-115.193172.6-76.7-86.7000110.7S463S463-F465 VanDerWaalsContact C-N 3.32Å; S463-F465 PolarHBondContact O-N 3.46Å
466R37.5Very low39Very low244 Ų244144.4 Ų144.492%0.92178%0.775SS**PPolyproline II helixtrans-90.1119.2160-78.6-161.8-172.2-119.86.5109.1
467T33.8Very low38.3Very low142 Ų142143.5 Ų143.587%0.87179%0.785SS**PPolyproline II helixtrans-95.8136.6151.435.60000109.3
468L31Very low37.4Very low180 Ų180144.5 Ų144.594%0.94280%0.797SS**PPolyproline II helixtrans-54.5142.2-175.6-68.7151.1000113
469N32.2Very low36.8Very low156 Ų156138.8 Ų138.883%0.83480%0.798SS**  trans-117.9145.9159.3-162.88.6000109.9N471N469-N471 PolarHBondContact O-N 2.7Å
470I37.7Very low36.4Very low149 Ų149138.4 Ų138.476%0.76480%0.803SS**SBendtrans-71.1105.2-173.3-75.1166.2000110.3
471N39.5Very low35.7Very low150 Ų150138.9 Ų138.980%0.80280%0.804SS**SBendtrans153.498.4149.7-89.810.9000108.2N469 Q473N469-N471 PolarHBondContact O-N 2.7Å; N471-Q473 PolarHBondContact O-N 3.43Å
472G41.8Very low35.3Very low82 Ų82141.7 Ų141.785%0.84581%0.814SS**  trans-65.9121.8-174.500000113.7
473Q30.8Very low34.5Very low191 Ų191139 Ų13989%0.89381%0.81SS**  trans-164.5136.2152.5-114.8163.7-1.300110.9N471N471-Q473 PolarHBondContact O-N 3.43Å
474V38.8Very low34.4Very low135 Ų135143.6 Ų143.682%0.81882%0.819SS**  trans-102.9145176.1-178.20000108.6
475P36.5Very low33.8Very low123 Ų123144.6 Ų144.680%0.79982%0.823SS**  trans-131.4151.4146.617.94000115.4
476T31.6Very low33.2Very low142 Ų142143.9 Ų143.987%0.87182%0.822SS**  trans-83.9157.4-168.4-32.40000113.5
477G30.9Very low32.7Very low61 Ų61138.8 Ų138.863%0.62982%0.818SS**  trans103.1132.2133.700000119.7
478D28.1Very low32.2Very low168 Ų168137.6 Ų137.690%0.89881%0.811SS**  trans88.992150.8-54.4-18.5000120.5
479G37.1Very low32Very low70 Ų70135.3 Ų135.372%0.72280%0.804SS**  trans-90.5166.3142.200000109.5
480P35.1Very low31.7Very low127 Ų127135.1 Ų135.183%0.82580%0.802SS**  -153.9-154.861.541.1-16.4000111.2
481P33.7Very low31Very low114 Ų114133.3 Ų133.374%0.7480%0.802SS**  cis-131.9166.2-2.839-19.1000117.8
482L33.7Very low30.6Very low159 Ų159133.6 Ų133.683%0.83280%0.803SS**  trans-63.5133.1166.7-127.676.4000111.3
483V26Very low29.9Very low124 Ų124136.7 Ų136.775%0.75281%0.806SS**  trans-130.2114.6158.4-176.30000108.8
484K32.8Very low29.9Very low188 Ų188131.7 Ų131.782%0.81780%0.798SS**  trans-87.1131.1163.7-79.1-179.9174.2178.40108
485T25.2Very low29.5Very low141 Ų141133.4 Ų133.487%0.86580%0.802SS**  trans-156.4162.1157.120.80000111.7
486Q24.3Very low29.2Very low176 Ų176132 Ų13282%0.82280%0.801SS**  trans-111151.7-139.2-176.1177.76.100111.2
487T26.1Very low29.2Very low137 Ų137132.3 Ų132.384%0.8480%0.802SS**  trans-68.2128.3177.5-1.50000111.7
488V22.4Very low29.3Very low117 Ų117136.9 Ų136.971%0.70981%0.805SS**  trans-136.9129.1166.8-179.20000109.4I490V488-I490 HydrophobicContact CG1-CD1 4.3Å; V488-I490 HydrophobicContact CG1-CG1 4.13Å
489T27.6Very low29.4Very low131 Ų131135.2 Ų135.280%0.80481%0.806SS**  trans-104.1123.4176.4-51.20000108.5
490I25Very low29.1Very low153 Ų153138.7 Ų138.779%0.78580%0.804SS**  trans-144.5139164.4-55.3-179.3000110.7V488V488-I490 HydrophobicContact CG1-CD1 4.3Å; V488-I490 HydrophobicContact CG1-CG1 4.13Å
491S24.6Very low28.8Very low110 Ų110140.7 Ų140.777%0.76981%0.806SS**  trans-78.2169.8-168.8-39.70000116.6
492D30.3Very low28.7Very low156 Ų156140.6 Ų140.683%0.83481%0.805SS**  trans-46.9135.9173.9-78.6-35.1000115.9
493T26.5Very low28.6Very low148 Ų148140 Ų14091%0.90881%0.808SS**  -169.8150.1127.950000112.4
494A31.8Very low28.8Very low86 Ų86143.5 Ų143.571%0.71181%0.813SS**  trans-63.8146.5-170.700000116.8
495N29.6Very low28.7Very low170 Ų170141.4 Ų141.491%0.90981%0.811SS**  -175.9135.8118.6-101.3-25.6000112.5
496A31.7Very low29Very low93 Ų93139.2 Ų139.277%0.76980%0.797SS**  trans-83.1141.9179.300000112.3
497V30.6Very low29.2Very low150 Ų150136.3 Ų136.391%0.90979%0.794SS**  trans-137121.6149.8176.80000108.4
498K33.9Very low29.7Very low157 Ų157136.6 Ų136.668%0.68379%0.788SS**  trans-66.8149.6-179.7-81.2-176.4171.3-165.10113.2E500K498-E500 WeakPolarHBondContact CE-OE1 3.07Å; K498-E500 IonicContact NZ-OE1 2.71Å; K498-E500 PolarHBondContact NZ-OE1 3.44Å
499S30.1Very low30Very low132 Ų132136.4 Ų136.492%0.92379%0.787SS**  trans-139.5118.7139.6-830000108.9
500E29.3Very low30.3Very low144 Ų144137.2 Ų137.267%0.67378%0.782SS**  trans-101.1140.3176.7-75.7171.8-176.400109.8K498K498-E500 WeakPolarHBondContact CE-OE1 3.07Å; K498-E500 IonicContact NZ-OE1 2.71Å; K498-E500 PolarHBondContact NZ-OE1 3.44Å
501I29Very low30.5Very low169 Ų169135 Ų13587%0.86778%0.776SS**  trans-139141.3146.4-63.6-174.3000107.4
502P32.2Very low30.8Very low112 Ų112137.2 Ų137.273%0.72777%0.774SS**  trans-107147.2-146.237.6-28.3000114
503T31Very low30.9Very low146 Ų146135.5 Ų135.590%0.89677%0.769SS**  trans-139.4140.3149.744.10000109.1
504K30.4Very low31.1Very low197 Ų197137.1 Ų137.186%0.85776%0.764SS**  trans-64.4128.6-163.7-76.1175.1164.7-178.90114.6
505D31Very low31.1Very low144 Ų144138.7 Ų138.777%0.7776%0.764SS**  trans48.994132.6-54.7-39.6000120.9
506V31.2Very low31.1Very low96 Ų96137.4 Ų137.458%0.58276%0.756SS**  -142.2136125.7-173.30000106.8I508V506-I508 PolarHBondContact O-N 2.8Å; V506-I508 VanDerWaalsContact O-N 3.1Å
507P29Very low31.1Very low114 Ų114139.2 Ų139.274%0.7476%0.758SS**  trans-71.5109.2-172.327.6-33.5000111.5V509P507-V509 PolarHBondContact O-N 2.99Å
508I35.6Very low30.9Very low143 Ų143142 Ų14273%0.73375%0.753SS**  trans-86.9100.3168.6-59.7172.6000107.4V506 H510V506-I508 PolarHBondContact O-N 2.8Å; V506-I508 VanDerWaalsContact O-N 3.1Å; I508-H510 PolarHBondContact O-N 2.94Å
509V29.9Very low30.9Very low113 Ų113143.8 Ų143.869%0.68576%0.764SS**  trans-82102.7166.1179.40000107.5P507 T511P507-V509 PolarHBondContact O-N 2.99Å; V509-T511 HydrophobicContact CG1-CG2 4.08Å; V509-T511 PolarHBondContact O-N 3.36Å
510H33.5Very low30.9Very low148 Ų148142 Ų14269%0.68576%0.758SS**  trans-82.5105.3170.8-124.275.1000108.7I508I508-H510 PolarHBondContact O-N 2.94Å
511T28.8Very low30.9Very low107 Ų107139.6 Ų139.666%0.65676%0.762SS**  trans-103.3101.1170.234.50000110V509 T513V509-T511 HydrophobicContact CG1-CG2 4.08Å; V509-T511 PolarHBondContact O-N 3.36Å; T511-T513 PolarHBondContact O-N 3.49Å
512E32Very low31Very low157 Ų157140.2 Ų140.273%0.73476%0.761SS**  trans-81.2111.5168.3-70.6-172.1174.600109.7
513T32Very low31Very low120 Ų120141.2 Ų141.274%0.73677%0.766SS**  trans-102.3106.8168.8-53.80000109T511T511-T513 PolarHBondContact O-N 3.49Å
514K29.8Very low31.4Very low182 Ų182142.8 Ų142.879%0.79176%0.763SS**  trans-84.6106.3170.6-76.6-177.4178.5175.30109.5
515T32.3Very low31.4Very low118 Ų118141.3 Ų141.372%0.72476%0.764SS**  trans-92.5115.2171.7-52.90000109.7
516I29.4Very low31.7Very low144 Ų144139.4 Ų139.474%0.73876%0.762SS**PPolyproline II helixtrans-83.3118.9169.1-61.4170.7000107.2Y518I516-Y518 PolarHBondContact O-N 2.92Å
517T31.8Very low32Very low131 Ų131142.5 Ų142.580%0.80478%0.776SS**PPolyproline II helixtrans-79.2117.7176.6-43.70000109.7
518Y27.2Very low32.3Very low207 Ų207140.8 Ų140.881%0.81278%0.779SS**PPolyproline II helixtrans-73.1142163.6-84.4-94.8000109.7I516 A520I516-Y518 PolarHBondContact O-N 2.92Å; Y518-A520 PolarHBondContact O-N 3.43Å
519E32.6Very low32.6Very low195 Ų195140.6 Ų140.691%0.91178%0.779SS**PPolyproline II helixtrans-52.8119.2169.4-75.7179.815000109.9A521E519-A521 PolarHBondContact O-N 3.34Å
520A30.8Very low33.2Very low96 Ų96142.1 Ų142.179%0.79378%0.782SS**PPolyproline II helixtrans-70122.9172.200000108.7Y518 Q522Y518-A520 PolarHBondContact O-N 3.43Å; A520-Q522 PolarHBondContact O-N 2.8Å
521A29.4Very low33.7Very low92 Ų92140 Ų14076%0.7678%0.776SS**PPolyproline II helixtrans-51.6132.6169.100000110E519 T523E519-A521 PolarHBondContact O-N 3.34Å; A521-T523 PolarHBondContact O-N 2.89Å
522Q32.2Very low34.8Very low182 Ų182138.5 Ų138.585%0.8577%0.769SS**PPolyproline II helixtrans-50.1124.4175.1-70.2-178.2-22.600110.5A520A520-Q522 PolarHBondContact O-N 2.8Å
523T31.2Very low36Very low134 Ų134131.9 Ų131.982%0.82274%0.743SS**  trans-105.4114.4153.534.80000106.2A521 D525A521-T523 PolarHBondContact O-N 2.89Å; T523-D525 PolarHBondContact O-N 3.2Å; T523-D525 VanDerWaalsContact O-N 3.1Å
524E38.9Very low37.6Very low179 Ų179130.6 Ų130.684%0.83673%0.734SS**  trans-64.5104.3176.1-68.8-175.1155.100109.2
525D31.7Very low39.4Very low166 Ų166126.5 Ų126.589%0.88872%0.721SS**  trans-139.7116.4155.1-90.3-36.1000108.3T523T523-D525 PolarHBondContact O-N 3.2Å; T523-D525 VanDerWaalsContact O-N 3.1Å
526S36Very low41.3Very low104 Ų104125.2 Ų125.273%0.72771%0.709SS**  trans-88.1131.8-168.1177.10000112.7
527N38.2Very low43.2Very low161 Ų161122.2 Ų122.286%0.86170%0.697SS**  trans79.6128.6159.9-64.8-8.8000118.6
528G36.1Very low45.4Very low78 Ų78119.6 Ų119.680%0.80469%0.689SS**  cis166.41111.200000111.1
529D41.2Very low47.3Very low138 Ų138115.2 Ų115.274%0.73868%0.675SS**  trans-164.886143.4177.932.1000106.7
530L42.8Very low49.1Very low145 Ų145110 Ų11076%0.75966%0.657SS**  trans-150.398.1173.2-64.7175.5000107.2P532L530-P532 HydrophobicContact CB-CB 4.01Å; L530-P532 HydrophobicContact CB-CG 3.88Å; L530-P532 HydrophobicContact CD1-CB 4.47Å; L530-P532 HydrophobicContact CD2-CB 4.03Å; L530-P532 HydrophobicContact CG-CB 4.38Å; L530-P532 WeakPolarHBondContact O-CD 3.24Å
531D42.7Very low51.1Low103 Ų103108.6 Ų108.655%0.55164%0.635SS**  -82.791.7119.4-170.726.7000104.4G533D531-G533 PolarHBondContact O-N 2.98Å
532P52Low53.2Low77 Ų77107.4 Ų107.450%0.562%0.619SS.*  trans-70.795.6177.527.8-19000103.7L530 V534L530-P532 HydrophobicContact CB-CB 4.01Å; L530-P532 HydrophobicContact CB-CG 3.88Å; L530-P532 HydrophobicContact CD1-CB 4.47Å; L530-P532 HydrophobicContact CD2-CB 4.03Å; L530-P532 HydrophobicContact CG-CB 4.38Å; L530-P532 WeakPolarHBondContact O-CD 3.24Å; P532-V534 PolarHBondContact O-N 3.1Å; P532-V534 VanDerWaalsContact O-N 3.08Å
533G57.3Low54.9Low18 Ų18101.8 Ų101.819%0.18660%0.6CS.*  trans-41.4125.6-177.600000109.3D531 L535 V558D531-G533 PolarHBondContact O-N 2.98Å; G533-L535 PolarHBondContact O-N 3.39Å; G533-V558 CarbonylContact C-O 3.58Å; G533-V558 VanDerWaalsContact C-O 3.26Å; G533-V558 WeakPolarHBondContact CA-O 3.44Å
534V65.4Low56.6Low93 Ų93102.2 Ų102.256%0.56459%0.593SS**EExtended strand (participates in β ladder)trans-59.3117.2-165.1177.70000108.2P532 L536 T557 V558P532-V534 PolarHBondContact O-N 3.1Å; P532-V534 VanDerWaalsContact O-N 3.08Å; V534-L536 PolarHBondContact O-N 3.4Å; V534-T557 CarbonylContact O-C 3.58Å; V534-T557 WeakPolarHBondContact O-CA 3.4Å; V534-V558 PolarHBondContact N-O 2.85Å; V534-V558 PolarHBondContact O-N 2.94Å
535L69.4Low57.9Low96 Ų9697.2 Ų97.250%0.50357%0.574SS.*EExtended strand (participates in β ladder)trans-65.6108.6174.6179.569.4000107.7G533 A538 T555 T557G533-L535 PolarHBondContact O-N 3.39Å; L535-A538 HydrophobicContact CD1-CB 4.48Å; L535-A538 HydrophobicContact CD2-CB 4.27Å; L535-T555 HydrophobicContact CD1-CG2 3.26Å; L535-T557 HydrophobicContact CD1-CG2 4.01Å
536L70.4Confident59.3Low91 Ų9196 Ų9648%0.47657%0.573SS.*EExtended strand (participates in β ladder)trans-78.2-47.3178.5-67.9-175.8000110.8V534 K556 V558V534-L536 PolarHBondContact O-N 3.4Å; L536-K556 HydrophobicContact CB-CB 4.44Å; L536-K556 HydrophobicContact CB-CG 4.47Å; L536-K556 HydrophobicContact CD1-CD 4.11Å; L536-K556 HydrophobicContact CD1-CG 4.22Å; L536-K556 PolarHBondContact N-O 2.77Å; L536-V558 HydrophobicContact CD1-CG2 3.36Å; L536-V558 HydrophobicContact CD2-CG2 4.22Å; L536-V558 HydrophobicContact CG-CG2 3.77Å
537T70.6Confident60.4Low81 Ų8192.8 Ų92.850%0.49755%0.551SS.*EExtended strand (participates in β ladder)trans-151.8139-175.158.90000110.4K556T537-K556 PolarHBondContact N-O 2.79Å; T537-K556 PolarHBondContact O-N 2.97Å; T537-K556 WeakPolarHBondContact OG1-CB 3.16Å
538A76.6Confident61.9Low75 Ų7585.8 Ų85.862%0.6251%0.514SS*.EExtended strand (participates in β ladder)trans-126127.5166.100000108.8L535 I554L535-A538 HydrophobicContact CD1-CB 4.48Å; L535-A538 HydrophobicContact CD2-CB 4.27Å; A538-I554 CarbonylContact C-O 3.53Å; A538-I554 WeakPolarHBondContact CA-O 3.27Å
539Q67.1Low63.8Low115 Ų11583.9 Ų83.954%0.53749%0.487SS..EExtended strand (participates in β ladder)trans-129.7133.7177.9-173.3176.9-2.500108.9I541 I554Q539-I541 HydrophobicContact CG-CG1 4.16Å; Q539-I554 HydrophobicContact CB-CB 4.47Å; Q539-I554 PolarHBondContact N-O 2.96Å; Q539-I554 PolarHBondContact O-N 3.06Å
540T71.1Confident65.4Low85 Ų8578.3 Ų78.352%0.52146%0.458SS..EExtended strand (participates in β ladder)trans-115.5128.6171.4-57.80000108.5T551 T552 Q553T540-T551 HydrophobicContact CG2-CG2 3.77Å; T540-T552 CarbonylContact C-O 3.56Å; T540-T552 WeakPolarHBondContact CA-O 3.34Å; T540-Q553 HydrophobicContact CG2-CG 4.14Å
541I73.5Confident67.1Low67 Ų6772.9 Ų72.934%0.34443%0.431SS..EExtended strand (participates in β ladder)trans-119.2117.6178-54.5173.3000107Q539 T551 T552 I554Q539-I541 HydrophobicContact CG-CG1 4.16Å; I541-T551 CarbonylContact O-C 3.26Å; I541-T551 WeakPolarHBondContact O-CA 3.39Å; I541-T552 PolarHBondContact N-O 3.32Å; I541-T552 PolarHBondContact O-N 3.41Å; I541-I554 HydrophobicContact CD1-CD1 4.26Å
542T72.6Confident68.7Low68 Ų6868.4 Ų68.442%0.41741%0.407SS..EExtended strand (participates in β ladder)trans-108.4131.5173.9-530000109T549 T550T542-T549 HydrophobicContact CG2-CG2 4.11Å; T542-T550 CarbonylContact C-O 3.52Å; T542-T550 WeakPolarHBondContact CA-O 3.35Å
543S67.4Low69.9Low63 Ų6369.2 Ų69.244%0.44140%0.404SS..EExtended strand (participates in β ladder)trans-127.8130.6175.6172.20000108.4T550S543-T550 PolarHBondContact N-O 3.05Å; S543-T550 PolarHBondContact O-N 3.16Å
544E67.4Low70.9Confident144 Ų14469.9 Ų69.967%0.67340%0.403SS*.EExtended strand (participates in β ladder)trans-114.2138177.6-70.9177.8-179.900109.6T549E544-T549 HydrophobicContact CG-CG2 3.84Å
545T65.6Low71.6Confident74 Ų7467.6 Ų67.645%0.45439%0.39SS..EExtended strand (participates in β ladder)trans-128.1165.7171.128.40000108.4S547 S548T545-S547 PolarHBondContact O-N 3.5Å; T545-S548 PolarHBondContact N-O 2.8Å; T545-S548 PolarHBondContact O-N 3.33Å; T545-S548 PolarHBondContact OG1-O 2.82Å; T545-S548 PolarHBondContact OG1-OG 2.77Å
546T61.5Low72Confident140 Ų14066.5 Ų66.586%0.85938%0.381SS*.THydrogen-bonded Turntrans-54.2-25.9-175.3-47.30000114.5
547S60.5Low72.5Confident37 Ų3763.9 Ų63.926%0.25937%0.369SS..THydrogen-bonded Turntrans-123.20.6-17955.80000114.4T545 I573 T574T545-S547 PolarHBondContact O-N 3.5Å; S547-I573 WeakPolarHBondContact O-CA 3.42Å; S547-T574 CarbonylContact C-O 3.57Å; S547-T574 PolarHBondContact O-N 2.82Å; S547-T574 VanDerWaalsContact O-O 3.13Å
548S69Low72.5Confident13 Ų1361.9 Ų61.99%0.09136%0.356CS..EExtended strand (participates in β ladder)trans-156145.8-178.979.90000114.7T545 V572T545-S548 PolarHBondContact N-O 2.8Å; T545-S548 PolarHBondContact O-N 3.33Å; T545-S548 PolarHBondContact OG1-O 2.82Å; T545-S548 PolarHBondContact OG1-OG 2.77Å; S548-V572 CarbonylContact C-O 3.59Å; S548-V572 WeakPolarHBondContact CA-O 3.48Å; S548-V572 WeakPolarHBondContact CB-O 3.39Å
549T76.2Confident72.3Confident39 Ų3964.3 Ų64.324%0.23935%0.353CS..EExtended strand (participates in β ladder)trans-111.9120.2170.7-57.60000109.4T542 E544 V572T542-T549 HydrophobicContact CG2-CG2 4.11Å; E544-T549 HydrophobicContact CG-CG2 3.84Å; T549-V572 PolarHBondContact N-O 3.39Å; T549-V572 PolarHBondContact O-N 3.19Å
550T74Confident72.3Confident20 Ų2062.3 Ų62.312%0.12336%0.363CS..EExtended strand (participates in β ladder)trans-110.1121.6178.7-63.80000110.5T542 S543 K569 R570 I571T542-T550 CarbonylContact C-O 3.52Å; T542-T550 WeakPolarHBondContact CA-O 3.35Å; S543-T550 PolarHBondContact N-O 3.05Å; S543-T550 PolarHBondContact O-N 3.16Å; T550-K569 HydrophobicContact CG2-CD 4.27Å; T550-K569 HydrophobicContact CG2-CG 4.01Å; T550-R570 CarbonylContact C-O 3.52Å; T550-R570 WeakPolarHBondContact CA-O 3.33Å; T550-I571 HydrophobicContact CG2-CG1 3.96Å
551T78.2Confident72Confident31 Ų3161.7 Ų61.719%0.1937%0.374CS..EExtended strand (participates in β ladder)trans-114.5119.7174-500000109.9T540 I541 K569 R570T540-T551 HydrophobicContact CG2-CG2 3.77Å; I541-T551 CarbonylContact O-C 3.26Å; I541-T551 WeakPolarHBondContact O-CA 3.39Å; T551-K569 WeakPolarHBondContact O-CA 3.42Å; T551-R570 PolarHBondContact N-O 2.8Å; T551-R570 PolarHBondContact O-N 3.27Å
552T76.6Confident71.3Confident10 Ų1064.7 Ų64.76%0.06139%0.389CS..EExtended strand (participates in β ladder)trans-111.6117.6177.7-50.90000109.6T540 I541 I554 I567 E568T540-T552 CarbonylContact C-O 3.56Å; T540-T552 WeakPolarHBondContact CA-O 3.34Å; I541-T552 PolarHBondContact N-O 3.32Å; I541-T552 PolarHBondContact O-N 3.41Å; T552-I554 HydrophobicContact CG2-CG1 4.13Å; T552-I567 HydrophobicContact CG2-CG2 3.66Å; T552-E568 CarbonylContact C-O 3.59Å; T552-E568 WeakPolarHBondContact CA-O 3.44Å
553Q77.4Confident71.2Confident94 Ų9464.6 Ų64.644%0.43939%0.392SS..EExtended strand (participates in β ladder)trans-102.7121.8173.1-66.5-175.9-0.800109.6T540 I567 E568T540-Q553 HydrophobicContact CG2-CG 4.14Å; Q553-I567 CarbonylContact O-C 3.55Å; Q553-I567 WeakPolarHBondContact O-CA 3.37Å; Q553-E568 HydrophobicContact CB-CB 4.48Å; Q553-E568 PolarHBondContact N-O 2.82Å; Q553-E568 PolarHBondContact O-N 2.78Å
554I78.8Confident71.6Confident32 Ų3267.2 Ų67.216%0.16440%0.397CS..EExtended strand (participates in β ladder)trans-112.7123178.4-55.2176.3000107.7A538 Q539 I541 T552 T565 R566 I567A538-I554 CarbonylContact C-O 3.53Å; A538-I554 WeakPolarHBondContact CA-O 3.27Å; Q539-I554 HydrophobicContact CB-CB 4.47Å; Q539-I554 PolarHBondContact N-O 2.96Å; Q539-I554 PolarHBondContact O-N 3.06Å; I541-I554 HydrophobicContact CD1-CD1 4.26Å; T552-I554 HydrophobicContact CG2-CG1 4.13Å; I554-T565 HydrophobicContact CG2-CG2 4.14Å; I554-R566 WeakPolarHBondContact CA-O 3.4Å; I554-I567 HydrophobicContact CD1-CD1 4.49Å; I554-I567 HydrophobicContact CG1-CD1 4.31Å; I554-I567 HydrophobicContact CG1-CG1 4.13Å; I554-I567 HydrophobicContact CG1-CG2 4.28Å; I554-I567 HydrophobicContact CG2-CG1 4.21Å
555T79.9Confident72.2Confident45 Ų4563.5 Ų63.528%0.27638%0.384SS..EExtended strand (participates in β ladder)trans-127.8122.7-178.2-50.20000109.1L535 T557 T565 R566L535-T555 HydrophobicContact CD1-CG2 3.26Å; T555-T557 HydrophobicContact CG2-CG2 4.16Å; T555-T565 CarbonylContact O-C 3.56Å; T555-T565 WeakPolarHBondContact O-CA 3.37Å; T555-R566 PolarHBondContact N-O 3.18Å; T555-R566 PolarHBondContact O-N 3.36Å
556K78.1Confident72.8Confident73 Ų7366.8 Ų66.832%0.31739%0.388SS..EExtended strand (participates in β ladder)trans-111.5122.3174.6-168.3176.6-178.3177.10109.9L536 T537 E564L536-K556 HydrophobicContact CB-CB 4.44Å; L536-K556 HydrophobicContact CB-CG 4.47Å; L536-K556 HydrophobicContact CD1-CD 4.11Å; L536-K556 HydrophobicContact CD1-CG 4.22Å; L536-K556 PolarHBondContact N-O 2.77Å; T537-K556 PolarHBondContact N-O 2.79Å; T537-K556 PolarHBondContact O-N 2.97Å; T537-K556 WeakPolarHBondContact OG1-CB 3.16Å; K556-E564 CarbonylContact C-O 3.52Å; K556-E564 WeakPolarHBondContact CA-O 3.49Å
557T79.9Confident73.6Confident36 Ų3662 Ų6222%0.22136%0.357CS..EExtended strand (participates in β ladder)trans-122.415117960.60000110.2V534 L535 T555 S563 E564V534-T557 CarbonylContact O-C 3.58Å; V534-T557 WeakPolarHBondContact O-CA 3.4Å; L535-T557 HydrophobicContact CD1-CG2 4.01Å; T555-T557 HydrophobicContact CG2-CG2 4.16Å; T557-S563 CarbonylContact O-C 3.56Å; T557-S563 WeakPolarHBondContact O-CA 3.47Å; T557-E564 PolarHBondContact N-O 2.76Å; T557-E564 PolarHBondContact O-N 3.38Å
558V71.4Confident74.5Confident39 Ų3964.8 Ų64.824%0.23637%0.366CS..EExtended strand (participates in β ladder)trans-116.4119.5171.9172.60000109G533 V534 L536 I562G533-V558 CarbonylContact C-O 3.58Å; G533-V558 VanDerWaalsContact C-O 3.26Å; G533-V558 WeakPolarHBondContact CA-O 3.44Å; V534-V558 PolarHBondContact N-O 2.85Å; V534-V558 PolarHBondContact O-N 2.94Å; L536-V558 HydrophobicContact CD1-CG2 3.36Å; L536-V558 HydrophobicContact CD2-CG2 4.22Å; L536-V558 HydrophobicContact CG-CG2 3.77Å; V558-I562 WeakPolarHBondContact CA-O 3.48Å
559K72.8Confident74.8Confident125 Ų12566.8 Ų66.854%0.54337%0.373SS..EExtended strand (participates in β ladder)trans-122.9122.1174.9-166.3174-177.11750108.9G561 I562K559-G561 VanDerWaalsContact C-N 3.25Å; K559-G561 PolarHBondContact O-N 2.78Å; K559-I562 PolarHBondContact N-O 2.94Å; K559-I562 PolarHBondContact O-N 2.86Å; K559-I562 VanDerWaalsContact O-N 3.14Å
560G67.4Low74.9Confident74 Ų7472.5 Ų72.576%0.76339%0.39SS*.THydrogen-bonded Turntrans58.730.3179.200000115.3I562G560-I562 VanDerWaalsContact C-N 3.33Å; G560-I562 PolarHBondContact O-N 3.26Å
561G64.3Low74.9Confident72 Ų7274 Ų7474%0.74240%0.397SS*.THydrogen-bonded Turntrans84.3-1.2-179.600000115.4K559K559-G561 VanDerWaalsContact C-N 3.25Å; K559-G561 PolarHBondContact O-N 2.78Å
562I57.8Low74.8Confident129 Ų12975.7 Ų75.766%0.66241%0.407SS*.EExtended strand (participates in β ladder)trans-101.2126.5175.4-56.6172.8000108.3V558 K559 G560V558-I562 WeakPolarHBondContact CA-O 3.48Å; K559-I562 PolarHBondContact N-O 2.94Å; K559-I562 PolarHBondContact O-N 2.86Å; K559-I562 VanDerWaalsContact O-N 3.14Å; G560-I562 VanDerWaalsContact C-N 3.33Å; G560-I562 PolarHBondContact O-N 3.26Å
563S70.7Confident74.6Confident67 Ų6777.4 Ų77.447%0.46942%0.415SS..EExtended strand (participates in β ladder)trans-86.3120.5175.366.80000111T557T557-S563 CarbonylContact O-C 3.56Å; T557-S563 WeakPolarHBondContact O-CA 3.47Å
564E76.6Confident74.1Confident117 Ų11777.2 Ų77.255%0.54742%0.42SS..EExtended strand (participates in β ladder)trans-106.2127174.5-174.4178-179.600109.7K556 T557K556-E564 CarbonylContact C-O 3.52Å; K556-E564 WeakPolarHBondContact CA-O 3.49Å; T557-E564 PolarHBondContact N-O 2.76Å; T557-E564 PolarHBondContact O-N 3.38Å
565T79.1Confident73.1Confident67 Ų6777.3 Ų77.341%0.41143%0.429SS..EExtended strand (participates in β ladder)trans-109.2120.3173.8-550000108.9I554 T555 I567I554-T565 HydrophobicContact CG2-CG2 4.14Å; T555-T565 CarbonylContact O-C 3.56Å; T555-T565 WeakPolarHBondContact O-CA 3.37Å; T565-I567 HydrophobicContact CG2-CG1 4.45Å
566R78.8Confident72.1Confident143 Ų14382.2 Ų82.254%0.5445%0.454SS..EExtended strand (participates in β ladder)trans-107.5133.3175.2-174.3179.1177.491.72.9109.6I554 T555I554-R566 WeakPolarHBondContact CA-O 3.4Å; T555-R566 PolarHBondContact N-O 3.18Å; T555-R566 PolarHBondContact O-N 3.36Å
567I77.8Confident71Confident40 Ų4083.7 Ų83.721%0.20548%0.48CS..EExtended strand (participates in β ladder)trans-121122.8173.6-56.5-172.1000108.3T552 Q553 I554 T565 H596 M599T552-I567 HydrophobicContact CG2-CG2 3.66Å; Q553-I567 CarbonylContact O-C 3.55Å; Q553-I567 WeakPolarHBondContact O-CA 3.37Å; I554-I567 HydrophobicContact CD1-CD1 4.49Å; I554-I567 HydrophobicContact CG1-CD1 4.31Å; I554-I567 HydrophobicContact CG1-CG1 4.13Å; I554-I567 HydrophobicContact CG1-CG2 4.28Å; I554-I567 HydrophobicContact CG2-CG1 4.21Å; T565-I567 HydrophobicContact CG2-CG1 4.45Å; I567-H596 VanDerWaalsContact CD1-CE1 3.42Å; I567-H596 WeakPolarHBondContact CD1-CE1 3.34Å; I567-H596 WeakPolarHBondContact CD1-NE2 3.29Å; I567-M599 HydrophobicContact CB-CE 4.06Å; I567-M599 HydrophobicContact CB-SD 4.33Å; I567-M599 HydrophobicContact CD1-CE 4.16Å; I567-M599 HydrophobicContact CD1-SD 3.39Å; I567-M599 WeakPolarHBondContact CD1-SD 3.39Å; I567-M599 HydrophobicContact CG1-CE 3.85Å; I567-M599 HydrophobicContact CG1-SD 3.79Å
568E79.8Confident69.9Low95 Ų9590 Ų9044%0.44451%0.512SS..EExtended strand (participates in β ladder)trans-115.1116.7173.6-176.5165.4173.500109.1T552 Q553T552-E568 CarbonylContact C-O 3.59Å; T552-E568 WeakPolarHBondContact CA-O 3.44Å; Q553-E568 HydrophobicContact CB-CB 4.48Å; Q553-E568 PolarHBondContact N-O 2.82Å; Q553-E568 PolarHBondContact O-N 2.78Å
569K75.2Confident69.6Low54 Ų5490.6 Ų90.624%0.23551%0.514CS..EExtended strand (participates in β ladder)trans-113.3117.6-178.9-166.7166.6-177.4-178.30109.6T550 T551 I571 A592T550-K569 HydrophobicContact CG2-CD 4.27Å; T550-K569 HydrophobicContact CG2-CG 4.01Å; T551-K569 WeakPolarHBondContact O-CA 3.42Å; K569-I571 HydrophobicContact CG-CD1 4.48Å; K569-I571 HydrophobicContact CG-CG1 4.41Å; K569-A592 HydrophobicContact CD-CB 3.79Å
570R78.9Confident69.5Low159 Ų15988.5 Ų88.560%0.651%0.508SS*.EExtended strand (participates in β ladder)trans-103.7126.6173.7178.3-178-67.5-110.80.4108.2T550 T551 V572T550-R570 CarbonylContact C-O 3.52Å; T550-R570 WeakPolarHBondContact CA-O 3.33Å; T551-R570 PolarHBondContact N-O 2.8Å; T551-R570 PolarHBondContact O-N 3.27Å; R570-V572 HydrophobicContact CG-CG2 4.19Å
571I74.6Confident69.6Low51 Ų5189.4 Ų89.426%0.26249%0.492SS..EExtended strand (participates in β ladder)trans-119.7122.3174.3-60.5144.1000106.5T550 K569 I573 A588T550-I571 HydrophobicContact CG2-CG1 3.96Å; K569-I571 HydrophobicContact CG-CD1 4.48Å; K569-I571 HydrophobicContact CG-CG1 4.41Å; I571-I573 HydrophobicContact CG2-CG1 4.11Å; I571-A588 HydrophobicContact CD1-CB 3.65Å; I571-A588 HydrophobicContact CG1-CB 4.37Å; I571-A588 HydrophobicContact CG2-CB 4.11Å
572V75.4Confident69.9Low68 Ų6887.9 Ų87.941%0.41247%0.467SS..EExtended strand (participates in β ladder)trans-108.2119.5174.7-176.30000106.3S548 T549 R570 T574S548-V572 CarbonylContact C-O 3.59Å; S548-V572 WeakPolarHBondContact CA-O 3.48Å; S548-V572 WeakPolarHBondContact CB-O 3.39Å; T549-V572 PolarHBondContact N-O 3.39Å; T549-V572 PolarHBondContact O-N 3.19Å; R570-V572 HydrophobicContact CG-CG2 4.19Å; V572-T574 HydrophobicContact CG1-CG2 4.24Å
573I72Confident70.6Confident46 Ų4688.1 Ų88.124%0.23647%0.466CS..EExtended strand (participates in β ladder)trans-101.9116.5177.9-57.8166.1000106.3S547 I571 V584 L585S547-I573 WeakPolarHBondContact O-CA 3.42Å; I571-I573 HydrophobicContact CG2-CG1 4.11Å; I573-V584 HydrophobicContact CD1-CB 4.05Å; I573-V584 HydrophobicContact CD1-CG1 3.56Å; I573-V584 HydrophobicContact CG1-CG1 3.82Å; I573-V584 HydrophobicContact CG2-CG1 3.97Å; I573-L585 HydrophobicContact CD1-CB 4.49Å
574T66.5Low70.6Confident89 Ų8986.5 Ų86.555%0.54645%0.453SS..  trans-111.5114.3176.345.50000107.4S547 V572S547-T574 CarbonylContact C-O 3.57Å; S547-T574 PolarHBondContact O-N 2.82Å; S547-T574 VanDerWaalsContact O-O 3.13Å; V572-T574 HydrophobicContact CG1-CG2 4.24Å
575G58.9Low70.2Confident34 Ų3483.4 Ų83.435%0.35144%0.44SS..  trans-143.5137.1-173.600000113.4
576D57.8Low69.8Low148 Ų14883.7 Ų83.779%0.79144%0.441SS*.  trans-73166.3163.4-64.4-25.1000110.2D578 I579D576-D578 PolarHBondContact O-N 2.76Å; D576-I579 PolarHBondContact O-N 3.11Å
577A54.7Low69.4Low104 Ų10481.1 Ų81.186%0.8644%0.435SS*.THydrogen-bonded Turntrans-53.4-3.6-160.600000119.2
578D56.6Low69Low168 Ų16879.8 Ų79.890%0.89843%0.43SS*.THydrogen-bonded Turntrans-109.210.2-173.1-68.4-28.3000114.8D576D576-D578 PolarHBondContact O-N 2.76Å
579I66.2Low68.3Low53 Ų5377.7 Ų77.727%0.27242%0.421SS..  trans-93.9129.2-179.5-55.4-171.6000111.9D576 H581 V584D576-I579 PolarHBondContact O-N 3.11Å; I579-H581 PolarHBondContact O-CE1 3.42Å; I579-H581 PolarHBondContact O-N 3.47Å; I579-H581 PolarHBondContact O-ND1 3.21Å; I579-V584 HydrophobicContact CG2-CG2 3.6Å
580D71.1Confident68.3Low80 Ų8080.5 Ų80.543%0.42843%0.434SS..  trans-74.592.7168.4-175.2-17.3000109.8D582 Q583 V584D580-D582 PolarHBondContact O-N 3.06Å; D580-D582 PolarHBondContact OD1-N 2.91Å; D580-Q583 HydrophobicContact CB-CB 4.16Å; D580-Q583 HydrophobicContact CB-CG 4.43Å; D580-Q583 PolarHBondContact O-N 2.79Å; D580-Q583 PolarHBondContact OD1-N 2.97Å; D580-Q583 VanDerWaalsContact OD1-N 3.15Å; D580-Q583 WeakPolarHBondContact OD2-CG 3.47Å; D580-Q583 PolarHBondContact OD2-NE2 3.14Å; D580-V584 WeakPolarHBondContact O-CG2 3.46Å; D580-V584 PolarHBondContact O-N 2.83Å; D580-V584 VanDerWaalsContact O-N 3.1Å
581H68.6Low67.8Low93 Ų9376.9 Ų76.943%0.43142%0.423SS..Hα-helixtrans-60.2-32.1-175.9-67.373.8000112.6I579 L585I579-H581 PolarHBondContact O-CE1 3.42Å; I579-H581 PolarHBondContact O-N 3.47Å; I579-H581 PolarHBondContact O-ND1 3.21Å; H581-L585 VanDerWaalsContact O-CB 3.31Å; H581-L585 WeakPolarHBondContact O-CB 3.48Å; H581-L585 PolarHBondContact O-N 2.81Å
582D70.6Confident67.5Low41 Ų4175.8 Ų75.822%0.21942%0.422CS..Hα-helixtrans-71.2-41.3179.4-79.3-6.1000110.5H432 D580 L585 V586H432-D582 IonicContact CE1-OD1 3.31Å; H432-D582 IonicContact CE1-OD2 2.64Å; H432-D582 PolarHBondContact CE1-OD2 3.18Å; H432-D582 IonicContact ND1-OD2 2.69Å; H432-D582 IonicContact NE2-OD2 2.78Å; D580-D582 PolarHBondContact O-N 3.06Å; D580-D582 PolarHBondContact OD1-N 2.91Å; D582-L585 PolarHBondContact O-N 3.08Å; D582-V586 WeakPolarHBondContact O-CB 3.37Å; D582-V586 WeakPolarHBondContact O-CG2 3.31Å; D582-V586 PolarHBondContact O-N 3.01Å
583Q73.3Confident67.1Low134 Ų13477.2 Ų77.263%0.62642%0.423SS*.Hα-helixtrans-64.8-42.6174.2-81-170.95300112.7D580 L585 V586 Q587D580-Q583 HydrophobicContact CB-CB 4.16Å; D580-Q583 HydrophobicContact CB-CG 4.43Å; D580-Q583 PolarHBondContact O-N 2.79Å; D580-Q583 PolarHBondContact OD1-N 2.97Å; D580-Q583 VanDerWaalsContact OD1-N 3.15Å; D580-Q583 WeakPolarHBondContact OD2-CG 3.47Å; D580-Q583 PolarHBondContact OD2-NE2 3.14Å; Q583-L585 VanDerWaalsContact C-N 3.33Å; Q583-L585 PolarHBondContact O-N 3.47Å; Q583-V586 PolarHBondContact O-N 3.07Å; Q583-Q587 WeakPolarHBondContact O-CB 3.06Å; Q583-Q587 PolarHBondContact O-N 3.47Å
584V69.2Low67.1Low33 Ų3381.2 Ų81.220%0.244%0.44CS..Hα-helixtrans-64.1-41.4178.61800000110.7I573 I579 D580 Q587 A588I573-V584 HydrophobicContact CD1-CB 4.05Å; I573-V584 HydrophobicContact CD1-CG1 3.56Å; I573-V584 HydrophobicContact CG1-CG1 3.82Å; I573-V584 HydrophobicContact CG2-CG1 3.97Å; I579-V584 HydrophobicContact CG2-CG2 3.6Å; D580-V584 WeakPolarHBondContact O-CG2 3.46Å; D580-V584 PolarHBondContact O-N 2.83Å; D580-V584 VanDerWaalsContact O-N 3.1Å; V584-Q587 PolarHBondContact O-N 2.9Å; V584-A588 WeakPolarHBondContact O-CB 3.44Å; V584-A588 PolarHBondContact O-N 2.88Å
585L68.3Low66.9Low52 Ų5282.1 Ų82.127%0.27244%0.438SS..Hα-helixtrans-64-44.5176-17962000112I573 H581 D582 Q583 Q587 A588 I589 V606I573-L585 HydrophobicContact CD1-CB 4.49Å; H581-L585 VanDerWaalsContact O-CB 3.31Å; H581-L585 WeakPolarHBondContact O-CB 3.48Å; H581-L585 PolarHBondContact O-N 2.81Å; D582-L585 PolarHBondContact O-N 3.08Å; Q583-L585 VanDerWaalsContact C-N 3.33Å; Q583-L585 PolarHBondContact O-N 3.47Å; L585-Q587 VanDerWaalsContact C-N 3.35Å; L585-Q587 PolarHBondContact O-N 3.2Å; L585-A588 PolarHBondContact O-N 2.88Å; L585-I589 HydrophobicContact CD1-CD1 4.03Å; L585-I589 HydrophobicContact CD1-CG1 4.34Å; L585-I589 HydrophobicContact CG-CD1 3.97Å; L585-I589 VanDerWaalsContact O-CG1 3.27Å; L585-I589 WeakPolarHBondContact O-CG1 3.39Å; L585-I589 PolarHBondContact O-N 3.47Å; L585-V606 HydrophobicContact CD2-CG2 4.42Å
586V71.3Confident67.4Low72 Ų7283.3 Ų83.344%0.43644%0.435SS..Hα-helixtrans-60.5-45.5177.1167.20000111L439 D582 Q583 I589 K590L439-V586 HydrophobicContact CD2-CG2 4.1Å; D582-V586 WeakPolarHBondContact O-CB 3.37Å; D582-V586 WeakPolarHBondContact O-CG2 3.31Å; D582-V586 PolarHBondContact O-N 3.01Å; Q583-V586 PolarHBondContact O-N 3.07Å; V586-I589 PolarHBondContact O-N 3.36Å; V586-K590 WeakPolarHBondContact O-CB 3.35Å; V586-K590 PolarHBondContact O-N 3.1Å
587Q71.6Confident67.8Low90 Ų9080.9 Ų80.942%0.42143%0.427SS..Hα-helixtrans-62.9-44.6178.5-176.259.924.700111.3Q583 V584 L585 I589 K590 E591Q583-Q587 WeakPolarHBondContact O-CB 3.06Å; Q583-Q587 PolarHBondContact O-N 3.47Å; V584-Q587 PolarHBondContact O-N 2.9Å; L585-Q587 VanDerWaalsContact C-N 3.35Å; L585-Q587 PolarHBondContact O-N 3.2Å; Q587-I589 PolarHBondContact O-N 3.43Å; Q587-K590 WeakPolarHBondContact O-CB 3.38Å; Q587-K590 PolarHBondContact O-N 3.49Å; Q587-E591 PolarHBondContact NE2-OE1 2.83Å; Q587-E591 WeakPolarHBondContact O-CG 3.33Å; Q587-E591 PolarHBondContact O-N 3Å
588A67.7Low68.3Low11 Ų1183.6 Ų83.69%0.09143%0.427CS..Hα-helixtrans-66.8-35.8-179.500000112.9I571 V584 L585 A592I571-A588 HydrophobicContact CD1-CB 3.65Å; I571-A588 HydrophobicContact CG1-CB 4.37Å; I571-A588 HydrophobicContact CG2-CB 4.11Å; V584-A588 WeakPolarHBondContact O-CB 3.44Å; V584-A588 PolarHBondContact O-N 2.88Å; L585-A588 PolarHBondContact O-N 2.88Å; A588-A592 WeakPolarHBondContact O-CB 3.49Å; A588-A592 PolarHBondContact O-N 2.94Å
589I66.5Low68.9Low51 Ų5179.4 Ų79.426%0.26240%0.403SS..Hα-helixtrans-66.8-41.8172.8-69.9169.8000110.8F443 L585 V586 Q587 A592 K593F443-I589 HydrophobicContact CD2-CG2 3.96Å; F443-I589 HydrophobicContact CE2-CG2 3.34Å; F443-I589 HydrophobicContact CZ-CG2 4.1Å; L585-I589 HydrophobicContact CD1-CD1 4.03Å; L585-I589 HydrophobicContact CD1-CG1 4.34Å; L585-I589 HydrophobicContact CG-CD1 3.97Å; L585-I589 VanDerWaalsContact O-CG1 3.27Å; L585-I589 WeakPolarHBondContact O-CG1 3.39Å; L585-I589 PolarHBondContact O-N 3.47Å; V586-I589 PolarHBondContact O-N 3.36Å; Q587-I589 PolarHBondContact O-N 3.43Å; I589-A592 PolarHBondContact O-N 3.44Å; I589-K593 PolarHBondContact O-N 2.98Å
590K73.9Confident68.8Low113 Ų11381.8 Ų81.849%0.49142%0.424SS..Hα-helixtrans-61.9-47.4178.1-173-177.3175.3-170.20111.4V586 Q587 A592 K593 E594V586-K590 WeakPolarHBondContact O-CB 3.35Å; V586-K590 PolarHBondContact O-N 3.1Å; Q587-K590 WeakPolarHBondContact O-CB 3.38Å; Q587-K590 PolarHBondContact O-N 3.49Å; K590-A592 VanDerWaalsContact C-N 3.31Å; K590-A592 PolarHBondContact O-N 3.39Å; K590-K593 PolarHBondContact O-N 3.28Å; K590-K593 VanDerWaalsContact O-N 3.16Å; K590-E594 VanDerWaalsContact CE-OE1 3.29Å; K590-E594 WeakPolarHBondContact CE-OE1 3.36Å; K590-E594 PolarHBondContact O-N 2.85Å
591E69.9Low68.5Low83 Ų8382.3 Ų82.339%0.38843%0.43SS..Hα-helixtrans-62-37.7176.3-72.3173.3-169.500112.4Q587 E594 Q595Q587-E591 PolarHBondContact NE2-OE1 2.83Å; Q587-E591 WeakPolarHBondContact O-CG 3.33Å; Q587-E591 PolarHBondContact O-N 3Å; E591-E594 PolarHBondContact O-N 3.47Å; E591-Q595 VanDerWaalsContact O-CG 3.31Å; E591-Q595 WeakPolarHBondContact O-CG 3.4Å; E591-Q595 PolarHBondContact O-N 3.36Å; E591-Q595 VanDerWaalsContact O-N 3.11Å
592A67.3Low68.3Low28 Ų2883.7 Ų83.723%0.23145%0.445CS..Hα-helixtrans-63.6-38.8174.500000112.9K569 A588 I589 K590K569-A592 HydrophobicContact CD-CB 3.79Å; A588-A592 WeakPolarHBondContact O-CB 3.49Å; A588-A592 PolarHBondContact O-N 2.94Å; I589-A592 PolarHBondContact O-N 3.44Å; K590-A592 VanDerWaalsContact C-N 3.31Å; K590-A592 PolarHBondContact O-N 3.39Å
593K66.4Low67.9Low98 Ų9889.5 Ų89.543%0.42647%0.469SS..Hα-helixtrans-72.8-36.5178-168.9174.8179.2177.70112S446 I589 K590 H596 P597S446-K593 PolarHBondContact O-NZ 3.28Å; I589-K593 PolarHBondContact O-N 2.98Å; K590-K593 PolarHBondContact O-N 3.28Å; K590-K593 VanDerWaalsContact O-N 3.16Å; K593-H596 CarbonylContact O-C 3.6Å; K593-H596 PolarHBondContact O-N 3.16Å; K593-P597 WeakPolarHBondContact O-CA 3.48Å
594E73.5Confident67.3Low130 Ų13087.1 Ų87.161%0.60746%0.463SS*.Hα-helixtrans-67.8-33.2176.2-75.7178.1-174.700112.6K590 E591 H596K590-E594 VanDerWaalsContact CE-OE1 3.29Å; K590-E594 WeakPolarHBondContact CE-OE1 3.36Å; K590-E594 PolarHBondContact O-N 2.85Å; E591-E594 PolarHBondContact O-N 3.47Å; E594-H596 VanDerWaalsContact C-N 3.33Å
595Q62.5Low66.9Low108 Ų10889.4 Ų89.451%0.50548%0.477SS..Hα-helixtrans-69.1-29.4175.8-75.4173.1-6.700113.2E591E591-Q595 VanDerWaalsContact O-CG 3.31Å; E591-Q595 WeakPolarHBondContact O-CG 3.4Å; E591-Q595 PolarHBondContact O-N 3.36Å; E591-Q595 VanDerWaalsContact O-N 3.11Å
596H67.6Low66.7Low60 Ų6091.3 Ų91.328%0.27849%0.49SS..  trans-137.768.2-175.8-58.4-59.4000111.8I567 K593 E594 D598 M599I567-H596 VanDerWaalsContact CD1-CE1 3.42Å; I567-H596 WeakPolarHBondContact CD1-CE1 3.34Å; I567-H596 WeakPolarHBondContact CD1-NE2 3.29Å; K593-H596 CarbonylContact O-C 3.6Å; K593-H596 PolarHBondContact O-N 3.16Å; E594-H596 VanDerWaalsContact C-N 3.33Å; H596-D598 PolarHBondContact O-N 3.19Å; H596-M599 HydrophobicContact CB-CB 4.25Å; H596-M599 HydrophobicContact CB-CG 4.16Å; H596-M599 HydrophobicContact CB-SD 4.05Å; H596-M599 PolarHBondContact O-N 3.16Å
597P67.1Low66.1Low96 Ų9694.7 Ų94.762%0.62350%0.501SS*.THydrogen-bonded Turntrans-65.3-23.5-172.526.1-35000113.8K593K593-P597 WeakPolarHBondContact O-CA 3.48Å
598D66.2Low65.4Low161 Ų16198.6 Ų98.686%0.86152%0.52SS*.THydrogen-bonded Turntrans-934.3-176.2-58.2-39.1000113.6H596H596-D598 PolarHBondContact O-N 3.19Å
599M67.8Low64.7Low80 Ų80106.7 Ų106.739%0.39456%0.555SS.*  trans-103.1139.2-178.3-69.3-169.466.300112.7I567 H596I567-M599 HydrophobicContact CB-CE 4.06Å; I567-M599 HydrophobicContact CB-SD 4.33Å; I567-M599 HydrophobicContact CD1-CE 4.16Å; I567-M599 HydrophobicContact CD1-SD 3.39Å; I567-M599 WeakPolarHBondContact CD1-SD 3.39Å; I567-M599 HydrophobicContact CG1-CE 3.85Å; I567-M599 HydrophobicContact CG1-SD 3.79Å; H596-M599 HydrophobicContact CB-CB 4.25Å; H596-M599 HydrophobicContact CB-CG 4.16Å; H596-M599 HydrophobicContact CB-SD 4.05Å; H596-M599 PolarHBondContact O-N 3.16Å
600S64.4Low63.9Low103 Ų103109.7 Ų109.772%0.7258%0.577SS**  trans-89.1132173.362.40000111.1T602S600-T602 PolarHBondContact O-N 3.39Å
601V64.8Low62.5Low91 Ų91113.5 Ų113.555%0.55260%0.596SS**  trans-81.4112.4178.2179.70000109F443 V604F443-V601 HydrophobicContact CE1-CG1 4.29Å; F443-V601 HydrophobicContact CZ-CB 4.44Å; F443-V601 HydrophobicContact CZ-CG1 4.32Å; F443-V601 HydrophobicContact CZ-CG2 4.26Å; V601-V604 HydrophobicContact CG1-CG2 3.68Å
602T63.7Low61.1Low122 Ų122115.1 Ų115.175%0.74861%0.606SS**  trans-90.3-21.6-176.559.30000113.7S600S600-T602 PolarHBondContact O-N 3.39Å
603K62.3Low59.9Low164 Ų164118.8 Ų118.871%0.71363%0.63SS**  trans-160.7136.6-176.8-166.8-177.5-176.4-168.70111.1V605K603-V605 HydrophobicContact CD-CG2 3.96Å; K603-V605 VanDerWaalsContact CE-CG2 3.43Å; K603-V605 HydrophobicContact CG-CG2 3.95Å
604V61.9Low58.8Low83 Ų83123.7 Ų123.750%0.50365%0.654SS.*  trans-123.5129.6168.8-177.70000108.1F443 V601 V606F443-V604 HydrophobicContact CE1-CG2 4.07Å; F443-V604 HydrophobicContact CZ-CG2 4.5Å; V601-V604 HydrophobicContact CG1-CG2 3.68Å; V604-V606 HydrophobicContact CG1-CG2 4.35Å
605V61.3Low57Low81 Ų81130 Ų13049%0.49168%0.684SS.*  trans-129.3124.1177.1-165.40000108.3K603 H607K603-V605 HydrophobicContact CD-CG2 3.96Å; K603-V605 VanDerWaalsContact CE-CG2 3.43Å; K603-V605 HydrophobicContact CG-CG2 3.95Å; V605-H607 WeakPolarHBondContact CG1-CE1 3.42Å
606V64Low56.7Low92 Ų92131.2 Ų131.256%0.55869%0.693SS**  trans-114.2123.6177.6-176.50000107L585 V604L585-V606 HydrophobicContact CD2-CG2 4.42Å; V604-V606 HydrophobicContact CG1-CG2 4.35Å
607H58.6Low56.2Low144 Ų144134.9 Ų134.967%0.66772%0.715SS**  trans-115.1129172.3-57.796.2000107V605V605-H607 WeakPolarHBondContact CG1-CE1 3.42Å
608Q56.8Low55.6Low172 Ų172137.1 Ų137.180%0.80472%0.72SS**  trans-100.9120.9171.4-174.3175.211.200107
609E52Low54.9Low180 Ų180135.6 Ų135.684%0.84171%0.712SS**  trans-115.8111.8176.1-66.5179.1-178.100106.6
610T49.4Very low54.1Low115 Ų115139.1 Ų139.171%0.70673%0.732SS**  trans-94.9114.5171.229.10000108.1I612T610-I612 PolarHBondContact O-N 3.45Å
611E45.3Very low53.4Low193 Ų193141.5 Ų141.590%0.90273%0.732SS**  trans-73.2120.9172.4-156169.9-154.900108
612I41.3Very low52.6Low117 Ų117145.1 Ų145.160%0.675%0.745SS**  trans-91.6108.5176.5-53.6160.7000105.5L417 T610 E614L417-I612 HydrophobicContact CD1-CD1 3.79Å; L417-I612 HydrophobicContact CD2-CD1 4.42Å; T610-I612 PolarHBondContact O-N 3.45Å; I612-E614 PolarHBondContact O-N 2.71Å
613S40.3Very low51.8Low105 Ų105146.9 Ų146.973%0.73475%0.745SS**  trans-61.1123.7170.7-3.90000108.7E615S613-E615 PolarHBondContact O-N 3.35Å; S613-E615 VanDerWaalsContact O-N 3.1Å
614E43.8Very low50.9Low200 Ų200145.5 Ų145.594%0.93575%0.748SS**  trans-72.397.8166.9-68.7-172.6160.200108.2I612I612-E614 PolarHBondContact O-N 2.71Å
615E36.3Very low49.9Very low264 Ų264151.2 Ų151.2100%1.23477%0.77SS**  trans-93.60159.5-99.7-168.3163.400111.5S613S613-E615 PolarHBondContact O-N 3.35Å; S613-E615 VanDerWaalsContact O-N 3.1Å

Retrieved 615 of 615 residues in 600 ms (Link to these results)