A0A075B6R3_HUMAN Loading...

Helicase with zinc finger

AlphaFold DB , UniProt , Accession A0A075B6R3, Species HUMAN (Homo sapiens, Human), Gene HELZ, Length 567 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M48.4Very low72Confident220 Ų22089.5 Ų89.5100%1.08440%0.397SS*.  0-18.10-111.3-146.1-71.900112.2
2E48.1Very low73.3Confident98 Ų9887.5 Ų87.546%0.45839%0.39SS..  trans-92.3-17.8-176.3-59.7-166.5128.100114.2R4 R5E2-R4 VanDerWaalsContact C-N 3.28Å; E2-R4 PolarHBondContact O-N 2.98Å; E2-R5 WeakPolarHBondContact O-CA 3.32Å; E2-R5 WeakPolarHBondContact O-CB 3.35Å; E2-R5 PolarHBondContact O-N 3.46Å; E2-R5 IonicContact OE1-CZ 2.63Å; E2-R5 IonicContact OE1-NH1 3.39Å; E2-R5 PolarHBondContact OE1-NH1 2.99Å; E2-R5 IonicContact OE1-NH2 3.9Å
3D52.8Low74.4Confident54 Ų5480.8 Ų80.829%0.28936%0.36SS..Hα-helixtrans-62.1-33.5174.9-48-80.4000112.9R5 Y39 P47D3-R5 PolarHBondContact O-N 3.28Å; D3-Y39 VanDerWaalsContact CG-OH 3.22Å; D3-Y39 WeakPolarHBondContact OD1-CE1 3.48Å; D3-Y39 VanDerWaalsContact OD1-CZ 3.31Å; D3-Y39 PolarHBondContact OD1-OH 3.3Å; D3-P47 HydrophobicContact CB-CG 4.08Å; D3-P47 VanDerWaalsContact OD1-CD 3.27Å; D3-P47 WeakPolarHBondContact OD1-CD 3.4Å
4R62.5Low75.3Confident212 Ų21275.5 Ų75.580%0.834%0.338SS*.Hα-helixtrans-71.9-14.1172.8-69.2-172.3-176.9-179.80.9113E2 K8E2-R4 VanDerWaalsContact C-N 3.28Å; E2-R4 PolarHBondContact O-N 2.98Å; R4-K8 WeakPolarHBondContact O-CB 3.19Å; R4-K8 PolarHBondContact O-N 3.13Å
5R74.1Confident76.1Confident118 Ų11877.3 Ų77.345%0.44535%0.347SS..Hα-helixtrans-77.1-45.8179.4-167.3-175.8-75.6148.7-0.6110.2E2 D3 K8 S9E2-R5 WeakPolarHBondContact O-CA 3.32Å; E2-R5 WeakPolarHBondContact O-CB 3.35Å; E2-R5 PolarHBondContact O-N 3.46Å; E2-R5 IonicContact OE1-CZ 2.63Å; E2-R5 IonicContact OE1-NH1 3.39Å; E2-R5 PolarHBondContact OE1-NH1 2.99Å; E2-R5 IonicContact OE1-NH2 3.9Å; D3-R5 PolarHBondContact O-N 3.28Å; R5-K8 PolarHBondContact O-N 2.86Å; R5-S9 WeakPolarHBondContact O-CB 3.46Å; R5-S9 PolarHBondContact O-N 2.83Å; R5-S9 PolarHBondContact O-OG 2.83Å
6A78.1Confident76.8Confident2 Ų272.9 Ų72.92%0.01733%0.328CS..Hα-helixtrans-64.3-44.617900000112.4S9 C10 L36 I55A6-S9 PolarHBondContact O-N 3Å; A6-C10 WeakPolarHBondContact O-CB 3.22Å; A6-C10 PolarHBondContact O-N 3.17Å; A6-L36 HydrophobicContact CB-CD2 3.81Å; A6-L36 HydrophobicContact CB-CG 4.06Å; A6-I55 HydrophobicContact CB-CG2 4.41Å
7E82.1Confident77.4Confident56 Ų5668.9 Ų68.926%0.26231%0.31SS..Hα-helixtrans-63.7-44.9176-171.2170.9-150.100111.4S9 C10 E11 R54 I55E7-S9 PolarHBondContact O-N 3.38Å; E7-C10 WeakPolarHBondContact O-CB 3.08Å; E7-C10 PolarHBondContact O-N 3.5Å; E7-C10 VanDerWaalsContact O-N 3.15Å; E7-E11 WeakPolarHBondContact O-CG 3.29Å; E7-E11 PolarHBondContact O-N 3.04Å; E7-R54 IonicContact OE1-NH1 3.47Å; E7-I55 HydrophobicContact CB-CD1 3.82Å; E7-I55 HydrophobicContact CG-CD1 4.25Å
8K85.1Confident77.8Confident129 Ų12971.5 Ų71.556%0.56132%0.321SS*.Hα-helixtrans-61.9-42.9177.9-174.4178.5-178.3-177.50112.4R4 R5 C10 E11 Q12R4-K8 WeakPolarHBondContact O-CB 3.19Å; R4-K8 PolarHBondContact O-N 3.13Å; R5-K8 PolarHBondContact O-N 2.86Å; K8-C10 VanDerWaalsContact C-N 3.33Å; K8-E11 PolarHBondContact O-N 3.43Å; K8-Q12 WeakPolarHBondContact O-CB 3.25Å; K8-Q12 VanDerWaalsContact O-CG 3.24Å; K8-Q12 WeakPolarHBondContact O-CG 3.39Å; K8-Q12 PolarHBondContact O-N 2.9Å
9S86.1Confident78.3Confident3 Ų377.1 Ų77.12%0.02134%0.339CS..Hα-helixtrans-65.5-35.7175.3-65.80000111.6R5 A6 E7 Q12 A13 E31R5-S9 WeakPolarHBondContact O-CB 3.46Å; R5-S9 PolarHBondContact O-N 2.83Å; R5-S9 PolarHBondContact O-OG 2.83Å; A6-S9 PolarHBondContact O-N 3Å; E7-S9 PolarHBondContact O-N 3.38Å; S9-Q12 PolarHBondContact O-N 3.27Å; S9-A13 WeakPolarHBondContact O-CB 3.47Å; S9-A13 PolarHBondContact O-N 2.84Å; S9-E31 PolarHBondContact OG-OE2 2.79Å
10C87.4Confident78.7Confident2 Ų280.2 Ų80.21%0.01436%0.355CS..Hα-helixtrans-66.2-40.8174.4-170.70000112.3A6 E7 K8 A13 C14 A32 I55 E58 S59A6-C10 WeakPolarHBondContact O-CB 3.22Å; A6-C10 PolarHBondContact O-N 3.17Å; E7-C10 WeakPolarHBondContact O-CB 3.08Å; E7-C10 PolarHBondContact O-N 3.5Å; E7-C10 VanDerWaalsContact O-N 3.15Å; K8-C10 VanDerWaalsContact C-N 3.33Å; C10-A13 WeakPolarHBondContact O-CB 3.43Å; C10-A13 PolarHBondContact O-N 2.78Å; C10-C14 PolarHBondContact O-N 2.68Å; C10-C14 VanDerWaalsContact O-N 3.11Å; C10-A32 HydrophobicContact CB-CB 4.45Å; C10-I55 HydrophobicContact CB-CG2 3.89Å; C10-E58 VanDerWaalsContact SG-CB 3.6Å; C10-S59 PolarHBondContact SG-OG 3.43Å
11E87.1Confident79.2Confident90 Ų9079.8 Ų79.842%0.42136%0.356SS..Hα-helixtrans-67.3-40.6175.3-67.9-165.3142.500112.5E7 K8 A13 C14 E15 K107E7-E11 WeakPolarHBondContact O-CG 3.29Å; E7-E11 PolarHBondContact O-N 3.04Å; K8-E11 PolarHBondContact O-N 3.43Å; E11-A13 VanDerWaalsContact C-N 3.3Å; E11-A13 PolarHBondContact O-N 3.11Å; E11-C14 WeakPolarHBondContact O-CB 3.45Å; E11-C14 PolarHBondContact O-N 2.96Å; E11-C14 VanDerWaalsContact O-N 3.16Å; E11-E15 PolarHBondContact O-N 3.04Å; E11-K107 IonicContact OE1-NZ 3.51Å; E11-K107 PolarHBondContact OE1-NZ 3.23Å
12Q87.8Confident81.1Confident66 Ų6671.2 Ų71.231%0.30831%0.312SS..Hα-helixtrans-61.3-38.3173-73.4174.9-26.200111.8K8 S9 C14 E15 S16 H28K8-Q12 WeakPolarHBondContact O-CB 3.25Å; K8-Q12 VanDerWaalsContact O-CG 3.24Å; K8-Q12 WeakPolarHBondContact O-CG 3.39Å; K8-Q12 PolarHBondContact O-N 2.9Å; S9-Q12 PolarHBondContact O-N 3.27Å; Q12-C14 PolarHBondContact O-N 2.86Å; Q12-E15 PolarHBondContact O-N 2.59Å; Q12-S16 PolarHBondContact O-N 2.66Å; Q12-S16 PolarHBondContact O-OG 3.19Å; Q12-H28 HydrophobicContact CB-CB 4.47Å
13A87.3Confident83.1Confident0 Ų073.5 Ų73.50%032%0.323CS..Hα-helixtrans-62.4-41.1173.700000112.4S9 C10 E11 S16 L17 H28 C29 Y62S9-A13 WeakPolarHBondContact O-CB 3.47Å; S9-A13 PolarHBondContact O-N 2.84Å; C10-A13 WeakPolarHBondContact O-CB 3.43Å; C10-A13 PolarHBondContact O-N 2.78Å; E11-A13 VanDerWaalsContact C-N 3.3Å; E11-A13 PolarHBondContact O-N 3.11Å; A13-S16 PolarHBondContact O-N 3.39Å; A13-L17 VanDerWaalsContact O-CB 3.32Å; A13-L17 WeakPolarHBondContact O-CB 3.22Å; A13-L17 PolarHBondContact O-N 2.97Å; A13-H28 HydrophobicContact CB-CB 3.8Å; A13-C29 VanDerWaalsContact CB-SG 3.53Å; A13-Y62 HydrophobicContact CB-CD2 4.23Å
14C87.2Confident84.7Confident7 Ų775.1 Ų75.15%0.04733%0.33CS..Hα-helixtrans-62.9-42175.5-171.70000111.8C10 E11 Q12 L17 K18 Y62C10-C14 PolarHBondContact O-N 2.68Å; C10-C14 VanDerWaalsContact O-N 3.11Å; E11-C14 WeakPolarHBondContact O-CB 3.45Å; E11-C14 PolarHBondContact O-N 2.96Å; E11-C14 VanDerWaalsContact O-N 3.16Å; Q12-C14 PolarHBondContact O-N 2.86Å; C14-L17 PolarHBondContact O-N 3.35Å; C14-K18 WeakPolarHBondContact O-CG 3.24Å; C14-K18 PolarHBondContact O-N 2.81Å; C14-K18 VanDerWaalsContact O-N 3.07Å; C14-Y62 HydrophobicContact CB-CD2 4.43Å; C14-Y62 HydrophobicContact CB-CE1 4.32Å; C14-Y62 HydrophobicContact CB-CE2 3.81Å
15E87.3Confident85.9Confident102 Ų10265 Ų6548%0.47729%0.292SS..Hα-helixtrans-65.4-45.8176.1-72.6-167.7-175.100112.7E11 Q12 L17 K18 R19E11-E15 PolarHBondContact O-N 3.04Å; Q12-E15 PolarHBondContact O-N 2.59Å; E15-L17 VanDerWaalsContact C-N 3.29Å; E15-L17 PolarHBondContact O-N 2.87Å; E15-K18 PolarHBondContact O-N 2.77Å; E15-R19 WeakPolarHBondContact O-CG 3.27Å; E15-R19 PolarHBondContact O-N 2.83Å; E15-R19 IonicContact OE2-CZ 2.7Å; E15-R19 IonicContact OE2-NH1 3.3Å; E15-R19 IonicContact OE2-NH2 3.47Å; E15-R19 PolarHBondContact OE2-NH2 2.58Å
16S88Confident86.6Confident7 Ų760.7 Ų60.75%0.04928%0.277CS..Hα-helixtrans-62.3-38.2177.1-64.50000111.6Q12 A13 K18 R19 Q20 D21Q12-S16 PolarHBondContact O-N 2.66Å; Q12-S16 PolarHBondContact O-OG 3.19Å; A13-S16 PolarHBondContact O-N 3.39Å; S16-K18 PolarHBondContact O-N 3.37Å; S16-R19 CarbonylContact O-C 3.51Å; S16-R19 PolarHBondContact O-N 2.84Å; S16-Q20 PolarHBondContact O-N 2.83Å; S16-Q20 VanDerWaalsContact O-N 3.13Å; S16-D21 PolarHBondContact O-N 2.85Å
17L86.7Confident87.2Confident5 Ų567.9 Ų67.93%0.02631%0.308CS..Hα-helixtrans-62.5-41.6174.4-169.166.3000112A13 C14 E15 R19 Q20 Y22 A25 Y62 A65 P110 V111 I114A13-L17 VanDerWaalsContact O-CB 3.32Å; A13-L17 WeakPolarHBondContact O-CB 3.22Å; A13-L17 PolarHBondContact O-N 2.97Å; C14-L17 PolarHBondContact O-N 3.35Å; E15-L17 VanDerWaalsContact C-N 3.29Å; E15-L17 PolarHBondContact O-N 2.87Å; L17-R19 VanDerWaalsContact C-N 3.32Å; L17-R19 PolarHBondContact O-N 3.09Å; L17-Q20 PolarHBondContact O-N 2.87Å; L17-Y22 HydrophobicContact CD1-CD1 3.88Å; L17-Y22 HydrophobicContact CD1-CE1 4Å; L17-A25 HydrophobicContact CB-CB 4.5Å; L17-Y62 HydrophobicContact CD2-CD1 3.6Å; L17-Y62 HydrophobicContact CD2-CE1 4.44Å; L17-Y62 HydrophobicContact CD2-CG 4.25Å; L17-A65 HydrophobicContact CD1-CB 4.12Å; L17-A65 HydrophobicContact CD2-CB 4.14Å; L17-P110 HydrophobicContact CD2-CB 4.23Å; L17-P110 HydrophobicContact CG-CB 4.44Å; L17-V111 HydrophobicContact CD2-CG2 3.94Å; L17-I114 HydrophobicContact CD1-CD1 3.78Å; L17-I114 HydrophobicContact CG-CD1 4.26Å
18K85.2Confident87.5Confident116 Ų11666.3 Ų66.350%0.50430%0.301SS..Hα-helixtrans-66-33.1174.8-73.2175.8-179.5-177.90112.6C14 E15 S16 Q20 P110C14-K18 WeakPolarHBondContact O-CG 3.24Å; C14-K18 PolarHBondContact O-N 2.81Å; C14-K18 VanDerWaalsContact O-N 3.07Å; E15-K18 PolarHBondContact O-N 2.77Å; S16-K18 PolarHBondContact O-N 3.37Å; K18-Q20 PolarHBondContact O-N 2.83Å; K18-P110 HydrophobicContact CG-CG 4.02Å
19R87.3Confident87.6Confident177 Ų17760.2 Ų60.267%0.66827%0.274SS*.THydrogen-bonded Turntrans-80.20.4175.1-66.8-179.1-168.9139.915.4113.7E15 S16 L17 D21E15-R19 WeakPolarHBondContact O-CG 3.27Å; E15-R19 PolarHBondContact O-N 2.83Å; E15-R19 IonicContact OE2-CZ 2.7Å; E15-R19 IonicContact OE2-NH1 3.3Å; E15-R19 IonicContact OE2-NH2 3.47Å; E15-R19 PolarHBondContact OE2-NH2 2.58Å; S16-R19 CarbonylContact O-C 3.51Å; S16-R19 PolarHBondContact O-N 2.84Å; L17-R19 VanDerWaalsContact C-N 3.32Å; L17-R19 PolarHBondContact O-N 3.09Å; R19-D21 PolarHBondContact O-N 3.29Å
20Q85.6Confident87.7Confident140 Ų14062.9 Ų62.965%0.65429%0.29SS*.THydrogen-bonded Turntrans62.423-176.5-52.3179.718.100114.1S16 L17 K18 Y22S16-Q20 PolarHBondContact O-N 2.83Å; S16-Q20 VanDerWaalsContact O-N 3.13Å; L17-Q20 PolarHBondContact O-N 2.87Å; K18-Q20 PolarHBondContact O-N 2.83Å; Q20-Y22 HydrophobicContact CB-CE2 4.16Å; Q20-Y22 WeakPolarHBondContact O-CD2 3.13Å; Q20-Y22 WeakPolarHBondContact O-CE2 3.11Å; Q20-Y22 PolarHBondContact O-N 2.9Å
21D89.1Confident87.7Confident71 Ų7166.6 Ų66.638%0.3831%0.308SS..  trans-93.781.4173.3-170.6-17000109.6S16 R19 M24 A25S16-D21 PolarHBondContact O-N 2.85Å; R19-D21 PolarHBondContact O-N 3.29Å; D21-M24 HydrophobicContact CB-CB 4.27Å; D21-M24 VanDerWaalsContact OD1-CB 3.25Å; D21-M24 WeakPolarHBondContact OD1-CB 3.45Å; D21-M24 PolarHBondContact OD1-N 2.74Å; D21-M24 VanDerWaalsContact OD1-N 3.14Å; D21-M24 WeakPolarHBondContact OD2-CB 3.49Å; D21-A25 WeakPolarHBondContact O-CB 3.47Å; D21-A25 PolarHBondContact O-N 3.29Å
22Y89.3Confident87.6Confident40 Ų4062.3 Ų62.316%0.15729%0.288CS..Hα-helixtrans-72-30.5-171.2-52.3-63.1000113.2L17 Q20 L26 Q69 I114L17-Y22 HydrophobicContact CD1-CD1 3.88Å; L17-Y22 HydrophobicContact CD1-CE1 4Å; Q20-Y22 HydrophobicContact CB-CE2 4.16Å; Q20-Y22 WeakPolarHBondContact O-CD2 3.13Å; Q20-Y22 WeakPolarHBondContact O-CE2 3.11Å; Q20-Y22 PolarHBondContact O-N 2.9Å; Y22-L26 WeakPolarHBondContact O-CG 3.5Å; Y22-L26 PolarHBondContact O-N 2.65Å; Y22-Q69 HydrophobicContact CD1-CB 3.94Å; Y22-Q69 HydrophobicContact CD1-CG 4.11Å; Y22-Q69 HydrophobicContact CD2-CB 3.74Å; Y22-Q69 HydrophobicContact CD2-CG 4.45Å; Y22-Q69 HydrophobicContact CE1-CB 3.97Å; Y22-Q69 HydrophobicContact CE1-CG 3.69Å; Y22-Q69 HydrophobicContact CE2-CB 3.75Å; Y22-Q69 HydrophobicContact CE2-CG 4.05Å; Y22-Q69 HydrophobicContact CG-CB 3.83Å; Y22-Q69 HydrophobicContact CG-CG 4.47Å; Y22-I114 HydrophobicContact CE1-CD1 3.99Å
23E88.6Confident87.5Confident146 Ų14660.5 Ų60.568%0.68228%0.28SS*.Hα-helixtrans-69.6-42176.3-67.6-173.8177.300111.1L26 K27 L70E23-L26 PolarHBondContact O-N 3.17Å; E23-K27 PolarHBondContact O-N 2.69Å; E23-K27 VanDerWaalsContact O-N 3.13Å; E23-L70 HydrophobicContact CG-CD1 4.33Å; E23-L70 HydrophobicContact CG-CD2 4.26Å
24M86.8Confident87.4Confident89 Ų8966 Ų6644%0.43831%0.309SS..Hα-helixtrans-69.5-37.4175.5-161.3170.3-155.800111.7D21 L26 K27 H28D21-M24 HydrophobicContact CB-CB 4.27Å; D21-M24 VanDerWaalsContact OD1-CB 3.25Å; D21-M24 WeakPolarHBondContact OD1-CB 3.45Å; D21-M24 PolarHBondContact OD1-N 2.74Å; D21-M24 VanDerWaalsContact OD1-N 3.14Å; D21-M24 WeakPolarHBondContact OD2-CB 3.49Å; M24-L26 PolarHBondContact O-N 3.22Å; M24-K27 PolarHBondContact O-N 2.67Å; M24-H28 PolarHBondContact O-CD2 2.88Å; M24-H28 PolarHBondContact O-N 2.78Å
25A88.1Confident87.1Confident0 Ų066.5 Ų66.50%031%0.313CS..Hα-helixtrans-59.7-43.4172.700000112L17 D21 K27 H28 C29 S66L17-A25 HydrophobicContact CB-CB 4.5Å; D21-A25 WeakPolarHBondContact O-CB 3.47Å; D21-A25 PolarHBondContact O-N 3.29Å; A25-K27 PolarHBondContact O-N 2.68Å; A25-H28 PolarHBondContact O-N 2.85Å; A25-C29 WeakPolarHBondContact O-CB 3.28Å; A25-C29 PolarHBondContact O-N 2.59Å; A25-C29 PolarHBondContact O-SG 2.77Å; A25-S66 WeakPolarHBondContact CB-OG 3.47Å
26L89.1Confident86.6Confident26 Ų2662.9 Ų62.914%0.13630%0.296CS..Hα-helixtrans-61.1-42.1174.8-76.6-177.4000112.7Y22 E23 M24 C29 T30 R63 F67 L70Y22-L26 WeakPolarHBondContact O-CG 3.5Å; Y22-L26 PolarHBondContact O-N 2.65Å; E23-L26 PolarHBondContact O-N 3.17Å; M24-L26 PolarHBondContact O-N 3.22Å; L26-C29 PolarHBondContact O-N 3.25Å; L26-T30 WeakPolarHBondContact O-CB 3.43Å; L26-T30 PolarHBondContact O-N 3.11Å; L26-T30 PolarHBondContact O-OG1 2.79Å; L26-R63 HydrophobicContact CD2-CB 4.45Å; L26-R63 HydrophobicContact CD2-CG 3.51Å; L26-F67 HydrophobicContact CD1-CD1 3.75Å; L26-F67 HydrophobicContact CD1-CE1 3.52Å; L26-F67 HydrophobicContact CD1-CZ 4.31Å; L26-F67 HydrophobicContact CD2-CD1 3.81Å; L26-F67 HydrophobicContact CD2-CD2 4.11Å; L26-F67 HydrophobicContact CD2-CE1 3.68Å; L26-F67 HydrophobicContact CD2-CE2 4Å; L26-F67 HydrophobicContact CD2-CG 4.01Å; L26-F67 HydrophobicContact CD2-CZ 3.78Å; L26-F67 HydrophobicContact CG-CD1 4.44Å; L26-F67 HydrophobicContact CG-CE1 4.27Å; L26-L70 HydrophobicContact CD1-CD1 3.4Å; L26-L70 HydrophobicContact CG-CD1 4.23Å
27K89.1Confident85.4Confident153 Ų15365.7 Ų65.767%0.66533%0.326SS*.Hα-helixtrans-61.6-46.7178.8-172.3179179.1-178.70110.9E23 M24 A25 T30 E31E23-K27 PolarHBondContact O-N 2.69Å; E23-K27 VanDerWaalsContact O-N 3.13Å; M24-K27 PolarHBondContact O-N 2.67Å; A25-K27 PolarHBondContact O-N 2.68Å; K27-T30 PolarHBondContact O-N 3.39Å; K27-E31 WeakPolarHBondContact O-CB 3.45Å; K27-E31 PolarHBondContact O-N 3.45Å
28H88.9Confident84.2Confident24 Ų2472.5 Ų72.511%0.11136%0.358CS..Hα-helixtrans-67.3-38177.7-71.1-49.5000113Q12 A13 M24 A25 T30 E31 A32Q12-H28 HydrophobicContact CB-CB 4.47Å; A13-H28 HydrophobicContact CB-CB 3.8Å; M24-H28 PolarHBondContact O-CD2 2.88Å; M24-H28 PolarHBondContact O-N 2.78Å; A25-H28 PolarHBondContact O-N 2.85Å; H28-T30 VanDerWaalsContact C-N 3.35Å; H28-T30 PolarHBondContact O-N 2.9Å; H28-E31 IonicContact ND1-OE2 3.2Å; H28-E31 PolarHBondContact O-N 2.79Å; H28-A32 WeakPolarHBondContact O-CB 3.39Å; H28-A32 PolarHBondContact O-N 3.25Å
29C88.5Confident82.8Confident0 Ų072 Ų720%035%0.353CS..Hα-helixtrans-62.9-41.7173.2-66.70000112A13 A25 L26 A32 L33 S59 R63A13-C29 VanDerWaalsContact CB-SG 3.53Å; A25-C29 WeakPolarHBondContact O-CB 3.28Å; A25-C29 PolarHBondContact O-N 2.59Å; A25-C29 PolarHBondContact O-SG 2.77Å; L26-C29 PolarHBondContact O-N 3.25Å; C29-A32 PolarHBondContact O-N 3.24Å; C29-L33 WeakPolarHBondContact O-CB 3.06Å; C29-L33 VanDerWaalsContact O-CG 3.31Å; C29-L33 WeakPolarHBondContact O-CG 3.41Å; C29-L33 PolarHBondContact O-N 3.17Å; C29-S59 PolarHBondContact SG-O 3.22Å; C29-R63 HydrophobicContact CB-CB 3.91Å; C29-R63 HydrophobicContact CB-CG 4.09Å
30T87.4Confident80.7Confident59 Ų5968.5 Ų68.536%0.36236%0.356SS..Hα-helixtrans-68.5-40.9179.9-540000111.1L26 K27 H28 L33 L34L26-T30 WeakPolarHBondContact O-CB 3.43Å; L26-T30 PolarHBondContact O-N 3.11Å; L26-T30 PolarHBondContact O-OG1 2.79Å; K27-T30 PolarHBondContact O-N 3.39Å; H28-T30 VanDerWaalsContact C-N 3.35Å; H28-T30 PolarHBondContact O-N 2.9Å; T30-L33 PolarHBondContact O-N 2.73Å; T30-L34 HydrophobicContact CG2-CD1 4.03Å; T30-L34 HydrophobicContact CG2-CG 4.38Å; T30-L34 WeakPolarHBondContact O-CB 3.22Å; T30-L34 VanDerWaalsContact O-CG 3.26Å; T30-L34 WeakPolarHBondContact O-CG 3.36Å; T30-L34 PolarHBondContact O-N 3.24Å
31E87.3Confident78.8Confident80 Ų8069.9 Ų69.937%0.37437%0.365SS..Hα-helixtrans-62.3-41.8173.9-173.3179.5-16300112.2S9 K27 H28 S35S9-E31 PolarHBondContact OG-OE2 2.79Å; K27-E31 WeakPolarHBondContact O-CB 3.45Å; K27-E31 PolarHBondContact O-N 3.45Å; H28-E31 IonicContact ND1-OE2 3.2Å; H28-E31 PolarHBondContact O-N 2.79Å; E31-S35 WeakPolarHBondContact O-CB 3.43Å; E31-S35 PolarHBondContact O-N 3.07Å; E31-S35 PolarHBondContact O-OG 2.7Å
32A85.9Confident76.6Confident0 Ų070 Ų700%038%0.375CS..Hα-helixtrans-61.6-48.317500000111.4C10 H28 C29 S35 L36C10-A32 HydrophobicContact CB-CB 4.45Å; H28-A32 WeakPolarHBondContact O-CB 3.39Å; H28-A32 PolarHBondContact O-N 3.25Å; C29-A32 PolarHBondContact O-N 3.24Å; A32-S35 PolarHBondContact O-N 2.82Å; A32-L36 WeakPolarHBondContact O-CG 3.19Å; A32-L36 PolarHBondContact O-N 3.24Å; A32-L36 VanDerWaalsContact O-N 3.13Å
33L85.2Confident74.4Confident29 Ų2975.1 Ų75.115%0.15241%0.406CS..Hα-helixtrans-69-35.8-179-68.9168000113.2C29 T30 L36 G37 K56 L60C29-L33 WeakPolarHBondContact O-CB 3.06Å; C29-L33 VanDerWaalsContact O-CG 3.31Å; C29-L33 WeakPolarHBondContact O-CG 3.41Å; C29-L33 PolarHBondContact O-N 3.17Å; T30-L33 PolarHBondContact O-N 2.73Å; L33-L36 PolarHBondContact O-N 2.87Å; L33-G37 PolarHBondContact O-N 2.67Å; L33-G37 VanDerWaalsContact O-N 3.08Å; L33-K56 HydrophobicContact CD2-CG 3.91Å; L33-L60 HydrophobicContact CD1-CD2 3.74Å; L33-L60 HydrophobicContact CD1-CG 4.22Å; L33-L60 HydrophobicContact CD2-CD2 4.37Å; L33-L60 HydrophobicContact CD2-CG 4.13Å
34L84.2Confident72.3Confident114 Ų11475.1 Ų75.160%0.59740%0.404SS*.Hα-helixtrans-67.1-39.7174-74.6172.3000111.9T30 L36 G37T30-L34 HydrophobicContact CG2-CD1 4.03Å; T30-L34 HydrophobicContact CG2-CG 4.38Å; T30-L34 WeakPolarHBondContact O-CB 3.22Å; T30-L34 VanDerWaalsContact O-CG 3.26Å; T30-L34 WeakPolarHBondContact O-CG 3.36Å; T30-L34 PolarHBondContact O-N 3.24Å; L34-L36 VanDerWaalsContact C-N 3.25Å; L34-L36 PolarHBondContact O-N 2.6Å; L34-G37 PolarHBondContact O-N 2.91Å
35S81.4Confident70.4Confident19 Ų1978 Ų7813%0.13343%0.426CS..Hα-helixtrans-62.8-34.8175.7-58.40000111.4E31 A32 Y39E31-S35 WeakPolarHBondContact O-CB 3.43Å; E31-S35 PolarHBondContact O-N 3.07Å; E31-S35 PolarHBondContact O-OG 2.7Å; A32-S35 PolarHBondContact O-N 2.82Å; S35-Y39 WeakPolarHBondContact O-CD2 3.37Å; S35-Y39 VanDerWaalsContact O-CE2 3.27Å; S35-Y39 WeakPolarHBondContact O-CE2 3.41Å
36L77.2Confident68.7Low26 Ų2680 Ų8014%0.13645%0.447CS..Hα-helixtrans-74.7-27.1175.2-65.5175.2000113.6A6 A32 L33 L34 Q38 Y39 I52 I55 K56A6-L36 HydrophobicContact CB-CD2 3.81Å; A6-L36 HydrophobicContact CB-CG 4.06Å; A32-L36 WeakPolarHBondContact O-CG 3.19Å; A32-L36 PolarHBondContact O-N 3.24Å; A32-L36 VanDerWaalsContact O-N 3.13Å; L33-L36 PolarHBondContact O-N 2.87Å; L34-L36 VanDerWaalsContact C-N 3.25Å; L34-L36 PolarHBondContact O-N 2.6Å; L36-Q38 VanDerWaalsContact C-N 3.32Å; L36-Q38 PolarHBondContact O-N 3.07Å; L36-Y39 WeakPolarHBondContact O-CD2 3.09Å; L36-I52 HydrophobicContact CD2-CG2 4.26Å; L36-I55 HydrophobicContact CD1-CB 4.35Å; L36-I55 HydrophobicContact CD1-CG2 4Å; L36-K56 HydrophobicContact CD1-CB 3.96Å; L36-K56 HydrophobicContact CD1-CG 4.47Å
37G63.5Low66.8Low65 Ų6580.6 Ų80.667%0.6745%0.452SS*.Hα-helixtrans-77.8-10.1-179.100000115.3L33 L34 Y39L33-G37 PolarHBondContact O-N 2.67Å; L33-G37 VanDerWaalsContact O-N 3.08Å; L34-G37 PolarHBondContact O-N 2.91Å; G37-Y39 VanDerWaalsContact C-N 3.31Å
38Q61.3Low65.2Low149 Ų14977 Ų7770%0.69645%0.445SS*.THydrogen-bonded Turntrans-85.60.4179.6-69176.2-0.500113.6L36L36-Q38 VanDerWaalsContact C-N 3.32Å; L36-Q38 PolarHBondContact O-N 3.07Å
39Y55.9Low64Low104 Ų10479.3 Ų79.341%0.40846%0.463SS..  trans-87113.9178.7-72-98.7000111.6D3 S35 L36 G37D3-Y39 VanDerWaalsContact CG-OH 3.22Å; D3-Y39 WeakPolarHBondContact OD1-CE1 3.48Å; D3-Y39 VanDerWaalsContact OD1-CZ 3.31Å; D3-Y39 PolarHBondContact OD1-OH 3.3Å; S35-Y39 WeakPolarHBondContact O-CD2 3.37Å; S35-Y39 VanDerWaalsContact O-CE2 3.27Å; S35-Y39 WeakPolarHBondContact O-CE2 3.41Å; L36-Y39 WeakPolarHBondContact O-CD2 3.09Å; G37-Y39 VanDerWaalsContact C-N 3.31Å
40S42.1Very low62.8Low105 Ų10585 Ų8573%0.73449%0.493SS*.  trans-91.8141.9166.3-178.20000110A42S40-A42 PolarHBondContact O-N 3.42Å
41M45.8Very low62Low168 Ų16886 Ų8683%0.82849%0.493SS*.THydrogen-bonded Turntrans-65.627.8-176.2-77.4-78-76.100115.4F44M41-F44 HydrophobicContact SD-CE2 4.44Å
42A42.7Very low61.5Low73 Ų7384.8 Ų84.860%0.60349%0.489SS*.THydrogen-bonded Turntrans-110.6-17.1-172.400000115.9S40S40-A42 PolarHBondContact O-N 3.42Å
43D42.5Very low61Low148 Ų14887 Ų8779%0.79150%0.499SS*.  trans-133.989.2-176.3-74.2-44.9000112.5T45D43-T45 PolarHBondContact O-N 3.21Å; D43-T45 VanDerWaalsContact O-N 3.11Å
44F45.4Very low60.9Low147 Ų14787 Ų8765%0.64550%0.497SS*.  trans-80.588.7173.7-89.5-83.8000111.6M41 P49M41-F44 HydrophobicContact SD-CE2 4.44Å; F44-P49 HydrophobicContact CE1-CG 4.49Å
45T47.6Very low60.9Low149 Ų14982 Ų8291%0.91447%0.471SS*.  trans-134.736.915248.60000111.2D43D43-T45 PolarHBondContact O-N 3.21Å; D43-T45 VanDerWaalsContact O-N 3.11Å
46G52.7Low61Low41 Ų4183.9 Ų83.942%0.42348%0.477SS..SBendtrans-124.1175.4-179.900000113.7
47P47.7Very low61.4Low39 Ų3983.6 Ų83.625%0.25348%0.475SS..  trans-59.7161.2-168.818.6-26.4000114.8D3D3-P47 HydrophobicContact CB-CG 4.08Å; D3-P47 VanDerWaalsContact OD1-CD 3.27Å; D3-P47 WeakPolarHBondContact OD1-CD 3.4Å
48C55.6Low62.6Low77 Ų7780.6 Ų80.652%0.5244%0.444SS..  trans-54136.5-177.4-169.90000111L50 E51C48-L50 PolarHBondContact O-N 2.93Å; C48-E51 PolarHBondContact O-N 2.8Å
49P63.3Low63.9Low74 Ų7473.5 Ų73.548%0.48141%0.41SS..Hα-helixtrans-49.4-29.4-177.1-30.735.2000115.5F44 E53F44-P49 HydrophobicContact CE1-CG 4.49Å; P49-E53 PolarHBondContact O-N 2.85Å
50L65.1Low65.5Low119 Ų11968.8 Ų68.862%0.62339%0.392SS*.Hα-helixtrans-69.8-29.1179.2-65.5170.5000113.9C48 R54C48-L50 PolarHBondContact O-N 2.93Å; L50-R54 WeakPolarHBondContact O-CB 3.11Å; L50-R54 PolarHBondContact O-N 3.05Å
51E70.8Confident67.8Low79 Ų7963.9 Ų63.937%0.36936%0.357SS..Hα-helixtrans-77.1-36.8-178.4-169.9158.5-13900111.6C48 R54 I55C48-E51 PolarHBondContact O-N 2.8Å; E51-R54 PolarHBondContact O-N 3.08Å; E51-I55 HydrophobicContact CG-CD1 4.34Å; E51-I55 VanDerWaalsContact O-CG1 3.3Å; E51-I55 WeakPolarHBondContact O-CG1 3.47Å; E51-I55 PolarHBondContact O-N 2.8Å
52I75.6Confident70Confident56 Ų5655.9 Ų55.929%0.28732%0.318SS..Hα-helixtrans-62.4-44.7172.1-69.8169.4000110.4L36 I55 K56L36-I52 HydrophobicContact CD2-CG2 4.26Å; I52-I55 PolarHBondContact O-N 2.79Å; I52-K56 WeakPolarHBondContact O-CB 3.47Å; I52-K56 PolarHBondContact O-N 2.72Å
53E75.6Confident72.3Confident46 Ų4654.5 Ų54.522%0.21530%0.297CS..Hα-helixtrans-65.8-40.4177.4-72.9-173.916700112.4P49 K56 I57 K90P49-E53 PolarHBondContact O-N 2.85Å; E53-K56 PolarHBondContact O-N 3.49Å; E53-I57 WeakPolarHBondContact O-CG1 3.49Å; E53-I57 PolarHBondContact O-N 3.22Å; E53-K90 WeakPolarHBondContact OE1-CD 3.44Å; E53-K90 WeakPolarHBondContact OE1-CE 3.25Å; E53-K90 IonicContact OE1-NZ 3.44Å; E53-K90 PolarHBondContact OE1-NZ 3.08Å
54R83.3Confident74.5Confident30 Ų3047.5 Ų47.511%0.11326%0.26CS..Hα-helixtrans-57.1-52.6173.2176.3-170.4151.8-125.1-19.2111.6E7 L50 E51 K56 I57 E58 V98E7-R54 IonicContact OE1-NH1 3.47Å; L50-R54 WeakPolarHBondContact O-CB 3.11Å; L50-R54 PolarHBondContact O-N 3.05Å; E51-R54 PolarHBondContact O-N 3.08Å; R54-K56 VanDerWaalsContact C-N 3.28Å; R54-K56 PolarHBondContact O-N 3.25Å; R54-I57 PolarHBondContact O-N 3.35Å; R54-E58 HydrophobicContact CG-CG 4.43Å; R54-E58 WeakPolarHBondContact CG-OE1 3.35Å; R54-E58 IonicContact CZ-OE1 3.06Å; R54-E58 IonicContact NE-OE1 3.92Å; R54-E58 PolarHBondContact NE-OE1 2.8Å; R54-E58 IonicContact NH2-OE1 2.74Å; R54-E58 PolarHBondContact NH2-OE1 2.87Å; R54-E58 VanDerWaalsContact NH2-OE1 3.12Å; R54-E58 IonicContact NH2-OE2 3.67Å; R54-E58 WeakPolarHBondContact O-CB 3.06Å; R54-E58 WeakPolarHBondContact O-CG 3.34Å; R54-E58 PolarHBondContact O-N 3.05Å; R54-V98 HydrophobicContact CB-CG2 4.09Å; R54-V98 HydrophobicContact CG-CG1 4.19Å; R54-V98 HydrophobicContact CG-CG2 4.37Å
55I83.5Confident76.6Confident9 Ų940.6 Ų40.65%0.04623%0.23CC..Hα-helixtrans-63.2-37.1-178.2-63.6164.6000110.8A6 E7 C10 L36 E51 I52 S59A6-I55 HydrophobicContact CB-CG2 4.41Å; E7-I55 HydrophobicContact CB-CD1 3.82Å; E7-I55 HydrophobicContact CG-CD1 4.25Å; C10-I55 HydrophobicContact CB-CG2 3.89Å; L36-I55 HydrophobicContact CD1-CB 4.35Å; L36-I55 HydrophobicContact CD1-CG2 4Å; E51-I55 HydrophobicContact CG-CD1 4.34Å; E51-I55 VanDerWaalsContact O-CG1 3.3Å; E51-I55 WeakPolarHBondContact O-CG1 3.47Å; E51-I55 PolarHBondContact O-N 2.8Å; I52-I55 PolarHBondContact O-N 2.79Å; I55-S59 VanDerWaalsContact O-CB 3.27Å; I55-S59 WeakPolarHBondContact O-CB 3.44Å; I55-S59 PolarHBondContact O-N 3.4Å; I55-S59 PolarHBondContact O-OG 3.43Å
56K84.3Confident78.7Confident58 Ų5833.5 Ų33.525%0.25219%0.186SC..Hα-helixtrans-62.4-49.3175.9-165.7-177.8-173.9-170.20111.6L33 L36 I52 E53 R54 S59 L60 E86L33-K56 HydrophobicContact CD2-CG 3.91Å; L36-K56 HydrophobicContact CD1-CB 3.96Å; L36-K56 HydrophobicContact CD1-CG 4.47Å; I52-K56 WeakPolarHBondContact O-CB 3.47Å; I52-K56 PolarHBondContact O-N 2.72Å; E53-K56 PolarHBondContact O-N 3.49Å; R54-K56 VanDerWaalsContact C-N 3.28Å; R54-K56 PolarHBondContact O-N 3.25Å; K56-S59 PolarHBondContact O-N 2.94Å; K56-L60 HydrophobicContact CG-CD1 4.26Å; K56-L60 VanDerWaalsContact O-CG 3.32Å; K56-L60 WeakPolarHBondContact O-CG 3.49Å; K56-L60 PolarHBondContact O-N 3.44Å; K56-E86 WeakPolarHBondContact CE-OE2 3.38Å; K56-E86 VanDerWaalsContact NZ-CD 3.28Å; K56-E86 IonicContact NZ-OE1 3.99Å; K56-E86 PolarHBondContact NZ-OE1 2.82Å; K56-E86 VanDerWaalsContact NZ-OE1 3.08Å; K56-E86 IonicContact NZ-OE2 3.27Å; K56-E86 PolarHBondContact NZ-OE2 3.42Å
57I85.7Confident80.4Confident20 Ų2033 Ų3310%0.10317%0.172CC..Hα-helixtrans-65.4-46.8179.7-69.2161.6000111E53 R54 S59 L60 L61 F95 V98E53-I57 WeakPolarHBondContact O-CG1 3.49Å; E53-I57 PolarHBondContact O-N 3.22Å; R54-I57 PolarHBondContact O-N 3.35Å; I57-S59 VanDerWaalsContact C-N 3.33Å; I57-S59 PolarHBondContact O-N 3.05Å; I57-L60 PolarHBondContact O-N 2.77Å; I57-L61 HydrophobicContact CG2-CD1 3.94Å; I57-L61 HydrophobicContact CG2-CG 4.44Å; I57-L61 WeakPolarHBondContact O-CG 3.27Å; I57-L61 PolarHBondContact O-N 3.13Å; I57-F95 HydrophobicContact CD1-CD2 4.05Å; I57-F95 HydrophobicContact CG1-CD2 4.37Å; I57-F95 HydrophobicContact CG2-CD2 3.95Å; I57-F95 HydrophobicContact CG2-CE2 3.76Å; I57-V98 HydrophobicContact CB-CG1 4.05Å; I57-V98 HydrophobicContact CD1-CB 4.38Å; I57-V98 HydrophobicContact CD1-CG2 4.11Å; I57-V98 HydrophobicContact CG2-CB 4.45Å; I57-V98 HydrophobicContact CG2-CG1 3.76Å
58E88.2Confident82.2Confident2 Ų231.4 Ų31.41%0.00916%0.162CC..Hα-helixtrans-56.5-47.8176.7-74.6-169-149.100110.9C10 R54 L60 L61 Y62 V98 M102C10-E58 VanDerWaalsContact SG-CB 3.6Å; R54-E58 HydrophobicContact CG-CG 4.43Å; R54-E58 WeakPolarHBondContact CG-OE1 3.35Å; R54-E58 IonicContact CZ-OE1 3.06Å; R54-E58 IonicContact NE-OE1 3.92Å; R54-E58 PolarHBondContact NE-OE1 2.8Å; R54-E58 IonicContact NH2-OE1 2.74Å; R54-E58 PolarHBondContact NH2-OE1 2.87Å; R54-E58 VanDerWaalsContact NH2-OE1 3.12Å; R54-E58 IonicContact NH2-OE2 3.67Å; R54-E58 WeakPolarHBondContact O-CB 3.06Å; R54-E58 WeakPolarHBondContact O-CG 3.34Å; R54-E58 PolarHBondContact O-N 3.05Å; E58-L60 PolarHBondContact O-N 3.25Å; E58-L61 PolarHBondContact O-N 3.42Å; E58-Y62 HydrophobicContact CB-CE2 4.02Å; E58-Y62 WeakPolarHBondContact O-CD2 3.45Å; E58-Y62 VanDerWaalsContact O-CG 3.31Å; E58-Y62 PolarHBondContact O-N 3.08Å; E58-Y62 VanDerWaalsContact O-N 3.07Å; E58-Y62 PolarHBondContact OE2-OH 3.29Å; E58-V98 HydrophobicContact CG-CG1 4.5Å; E58-M102 HydrophobicContact CB-CE 4.35Å; E58-M102 HydrophobicContact CB-SD 4.47Å; E58-M102 HydrophobicContact CG-CE 3.97Å; E58-M102 HydrophobicContact CG-CG 3.78Å; E58-M102 HydrophobicContact CG-SD 3.67Å
59S89.3Confident83.7Confident0 Ų030.7 Ų30.70%015%0.151CC..Hα-helixtrans-64.7-39.7-178.7-57.30000112.7C10 C29 I55 K56 I57 R63C10-S59 PolarHBondContact SG-OG 3.43Å; C29-S59 PolarHBondContact SG-O 3.22Å; I55-S59 VanDerWaalsContact O-CB 3.27Å; I55-S59 WeakPolarHBondContact O-CB 3.44Å; I55-S59 PolarHBondContact O-N 3.4Å; I55-S59 PolarHBondContact O-OG 3.43Å; K56-S59 PolarHBondContact O-N 2.94Å; I57-S59 VanDerWaalsContact C-N 3.33Å; I57-S59 PolarHBondContact O-N 3.05Å; S59-R63 VanDerWaalsContact O-CB 3.31Å; S59-R63 WeakPolarHBondContact O-CB 3.27Å; S59-R63 PolarHBondContact O-N 3.46Å
60L89.3Confident84.8Confident5 Ų530.4 Ų30.43%0.02615%0.145CC..Hα-helixtrans-67.2-39.6176.4-72167.5000111.8L33 K56 I57 E58 R63 I64 V83L33-L60 HydrophobicContact CD1-CD2 3.74Å; L33-L60 HydrophobicContact CD1-CG 4.22Å; L33-L60 HydrophobicContact CD2-CD2 4.37Å; L33-L60 HydrophobicContact CD2-CG 4.13Å; K56-L60 HydrophobicContact CG-CD1 4.26Å; K56-L60 VanDerWaalsContact O-CG 3.32Å; K56-L60 WeakPolarHBondContact O-CG 3.49Å; K56-L60 PolarHBondContact O-N 3.44Å; I57-L60 PolarHBondContact O-N 2.77Å; E58-L60 PolarHBondContact O-N 3.25Å; L60-R63 PolarHBondContact O-N 3.23Å; L60-I64 WeakPolarHBondContact O-CD1 3.25Å; L60-I64 VanDerWaalsContact O-CG1 3.23Å; L60-I64 WeakPolarHBondContact O-CG1 3.36Å; L60-I64 PolarHBondContact O-N 2.94Å; L60-V83 HydrophobicContact CB-CG2 3.33Å; L60-V83 HydrophobicContact CD1-CG2 3.64Å; L60-V83 HydrophobicContact CG-CG2 4.05Å
61L90.3Very high85.7Confident1 Ų132 Ų321%0.00515%0.147CC..Hα-helixtrans-64.9-41.6177.4-70.7172.8000112.5I57 E58 R63 A65 V83 L99 M102 V111 L135I57-L61 HydrophobicContact CG2-CD1 3.94Å; I57-L61 HydrophobicContact CG2-CG 4.44Å; I57-L61 WeakPolarHBondContact O-CG 3.27Å; I57-L61 PolarHBondContact O-N 3.13Å; E58-L61 PolarHBondContact O-N 3.42Å; L61-R63 VanDerWaalsContact C-N 3.32Å; L61-A65 PolarHBondContact O-N 3.32Å; L61-A65 VanDerWaalsContact O-N 3.08Å; L61-V83 HydrophobicContact CD2-CG1 4.37Å; L61-L99 HydrophobicContact CD1-CD2 3.62Å; L61-M102 HydrophobicContact CD1-CE 4.04Å; L61-M102 HydrophobicContact CD1-SD 3.68Å; L61-V111 HydrophobicContact CB-CG1 4.33Å; L61-L135 HydrophobicContact CD2-CD1 3.99Å; L61-L135 HydrophobicContact CD2-CD2 3.98Å
62Y91.6Very high86.4Confident0 Ų031 Ų310%014%0.144CC..Hα-helixtrans-66.6-35.4173.8-58-37000112.1A13 C14 L17 E58 A65 S66 M102 K107 V111A13-Y62 HydrophobicContact CB-CD2 4.23Å; C14-Y62 HydrophobicContact CB-CD2 4.43Å; C14-Y62 HydrophobicContact CB-CE1 4.32Å; C14-Y62 HydrophobicContact CB-CE2 3.81Å; L17-Y62 HydrophobicContact CD2-CD1 3.6Å; L17-Y62 HydrophobicContact CD2-CE1 4.44Å; L17-Y62 HydrophobicContact CD2-CG 4.25Å; E58-Y62 HydrophobicContact CB-CE2 4.02Å; E58-Y62 WeakPolarHBondContact O-CD2 3.45Å; E58-Y62 VanDerWaalsContact O-CG 3.31Å; E58-Y62 PolarHBondContact O-N 3.08Å; E58-Y62 VanDerWaalsContact O-N 3.07Å; E58-Y62 PolarHBondContact OE2-OH 3.29Å; Y62-A65 PolarHBondContact O-N 2.9Å; Y62-S66 WeakPolarHBondContact O-CB 3.29Å; Y62-S66 PolarHBondContact O-N 3.43Å; Y62-S66 PolarHBondContact O-OG 2.84Å; Y62-M102 HydrophobicContact CE1-CE 3.81Å; Y62-K107 WeakPolarHBondContact OH-CB 3.42Å; Y62-V111 HydrophobicContact CD1-CG2 3.63Å; Y62-V111 HydrophobicContact CE1-CG2 3.96Å
63R90.9Very high86.6Confident44 Ų4430.8 Ų30.817%0.16614%0.14CC..Hα-helixtrans-66.7-44176.9-159.1168.169.7178.4-1.1112L26 C29 S59 L60 L61 S66 F67 D79L26-R63 HydrophobicContact CD2-CB 4.45Å; L26-R63 HydrophobicContact CD2-CG 3.51Å; C29-R63 HydrophobicContact CB-CB 3.91Å; C29-R63 HydrophobicContact CB-CG 4.09Å; S59-R63 VanDerWaalsContact O-CB 3.31Å; S59-R63 WeakPolarHBondContact O-CB 3.27Å; S59-R63 PolarHBondContact O-N 3.46Å; L60-R63 PolarHBondContact O-N 3.23Å; L61-R63 VanDerWaalsContact C-N 3.32Å; R63-S66 PolarHBondContact O-N 3.48Å; R63-F67 HydrophobicContact CG-CD2 3.99Å; R63-F67 HydrophobicContact CG-CE2 3.59Å; R63-F67 HydrophobicContact CG-CZ 4.28Å; R63-F67 WeakPolarHBondContact O-CD2 3.42Å; R63-F67 PolarHBondContact O-N 2.95Å; R63-D79 IonicContact CZ-OD1 2.65Å; R63-D79 IonicContact CZ-OD2 3.68Å; R63-D79 IonicContact NE-OD1 3.1Å; R63-D79 IonicContact NE-OD2 3.9Å; R63-D79 PolarHBondContact NE-OD2 3.38Å; R63-D79 VanDerWaalsContact NH2-CG 3.27Å; R63-D79 IonicContact NH2-OD1 2.89Å; R63-D79 PolarHBondContact NH2-OD1 3.41Å; R63-D79 IonicContact NH2-OD2 3.14Å; R63-D79 PolarHBondContact NH2-OD2 2.74Å
64I89.5Confident86.9Confident2 Ų232.6 Ų32.61%0.0115%0.154CC..Hα-helixtrans-57.6-50.7172.9-68.3162.5000110.3L60 S66 F67 L68 A76 D79 C80 V83 L132 L135L60-I64 WeakPolarHBondContact O-CD1 3.25Å; L60-I64 VanDerWaalsContact O-CG1 3.23Å; L60-I64 WeakPolarHBondContact O-CG1 3.36Å; L60-I64 PolarHBondContact O-N 2.94Å; I64-S66 VanDerWaalsContact C-N 3.29Å; I64-S66 PolarHBondContact O-N 2.77Å; I64-F67 PolarHBondContact O-N 3.49Å; I64-L68 HydrophobicContact CG2-CD1 3.89Å; I64-L68 HydrophobicContact CG2-CG 4.37Å; I64-L68 VanDerWaalsContact O-CG 3.26Å; I64-L68 WeakPolarHBondContact O-CG 3.28Å; I64-L68 PolarHBondContact O-N 2.63Å; I64-A76 HydrophobicContact CG2-CB 4.5Å; I64-D79 HydrophobicContact CD1-CB 4.03Å; I64-D79 HydrophobicContact CG1-CB 3.51Å; I64-C80 HydrophobicContact CD1-CB 4.19Å; I64-V83 HydrophobicContact CD1-CG2 4.13Å; I64-L132 HydrophobicContact CG2-CD2 4.02Å; I64-L135 HydrophobicContact CD1-CD2 4.13Å
65A89Confident86.9Confident1 Ų135.1 Ų35.11%0.00817%0.167CC..Hα-helixtrans-58-42.4178.600000112.1L17 L61 Y62 L68 Q69 V111 I114L17-A65 HydrophobicContact CD1-CB 4.12Å; L17-A65 HydrophobicContact CD2-CB 4.14Å; L61-A65 PolarHBondContact O-N 3.32Å; L61-A65 VanDerWaalsContact O-N 3.08Å; Y62-A65 PolarHBondContact O-N 2.9Å; A65-L68 PolarHBondContact O-N 2.73Å; A65-Q69 PolarHBondContact O-N 3.09Å; A65-V111 HydrophobicContact CB-CG1 4.29Å; A65-V111 HydrophobicContact CB-CG2 4.29Å; A65-I114 HydrophobicContact CB-CB 4.31Å; A65-I114 HydrophobicContact CB-CD1 4.13Å; A65-I114 HydrophobicContact CB-CG2 3.88Å; A65-I114 WeakPolarHBondContact O-CG2 3.3Å
66S90.6Very high86.9Confident0 Ų034.7 Ų34.70%017%0.165CC..Hα-helixtrans-66.7-43178.9-54.40000112.1A25 Y62 R63 I64 L68 Q69 L70A25-S66 WeakPolarHBondContact CB-OG 3.47Å; Y62-S66 WeakPolarHBondContact O-CB 3.29Å; Y62-S66 PolarHBondContact O-N 3.43Å; Y62-S66 PolarHBondContact O-OG 2.84Å; R63-S66 PolarHBondContact O-N 3.48Å; I64-S66 VanDerWaalsContact C-N 3.29Å; I64-S66 PolarHBondContact O-N 2.77Å; S66-L68 VanDerWaalsContact C-N 3.35Å; S66-L68 PolarHBondContact O-N 3.28Å; S66-Q69 PolarHBondContact O-N 3.29Å; S66-L70 WeakPolarHBondContact O-CG 3.39Å; S66-L70 PolarHBondContact O-N 3.37Å
67F89Confident86.8Confident30 Ų3032.7 Ų32.713%0.13216%0.157CC..Hα-helixtrans-64.4-36.6175.6-77.7-44.9000113.1L26 R63 I64 Q69 L70 K71 N72 Q75 A76L26-F67 HydrophobicContact CD1-CD1 3.75Å; L26-F67 HydrophobicContact CD1-CE1 3.52Å; L26-F67 HydrophobicContact CD1-CZ 4.31Å; L26-F67 HydrophobicContact CD2-CD1 3.81Å; L26-F67 HydrophobicContact CD2-CD2 4.11Å; L26-F67 HydrophobicContact CD2-CE1 3.68Å; L26-F67 HydrophobicContact CD2-CE2 4Å; L26-F67 HydrophobicContact CD2-CG 4.01Å; L26-F67 HydrophobicContact CD2-CZ 3.78Å; L26-F67 HydrophobicContact CG-CD1 4.44Å; L26-F67 HydrophobicContact CG-CE1 4.27Å; R63-F67 HydrophobicContact CG-CD2 3.99Å; R63-F67 HydrophobicContact CG-CE2 3.59Å; R63-F67 HydrophobicContact CG-CZ 4.28Å; R63-F67 WeakPolarHBondContact O-CD2 3.42Å; R63-F67 PolarHBondContact O-N 2.95Å; I64-F67 PolarHBondContact O-N 3.49Å; F67-Q69 VanDerWaalsContact C-N 3.33Å; F67-Q69 PolarHBondContact O-N 3.08Å; F67-L70 CarbonylContact O-C 3.5Å; F67-L70 PolarHBondContact O-N 3.34Å; F67-K71 PolarHBondContact O-N 2.72Å; F67-K71 VanDerWaalsContact O-N 3.11Å; F67-N72 HydrophobicContact CB-CB 4.35Å; F67-N72 HydrophobicContact CD1-CB 3.92Å; F67-N72 HydrophobicContact CG-CB 4.49Å; F67-N72 PolarHBondContact O-N 2.97Å; F67-Q75 HydrophobicContact CD1-CB 4.28Å; F67-Q75 HydrophobicContact CD2-CB 3.81Å; F67-Q75 HydrophobicContact CE1-CB 4.19Å; F67-Q75 HydrophobicContact CE2-CB 3.68Å; F67-Q75 HydrophobicContact CG-CB 4.12Å; F67-Q75 HydrophobicContact CZ-CB 3.9Å; F67-Q75 HydrophobicContact CZ-CG 4.31Å; F67-A76 HydrophobicContact CB-CB 3.83Å
68L85.7Confident86.7Confident6 Ų636.6 Ų36.63%0.03118%0.175CC..Hα-helixtrans-64.8-36.2175.9-70.6171.7000112.4I64 A65 S66 K71 Y73 A76 I114 L115 L132I64-L68 HydrophobicContact CG2-CD1 3.89Å; I64-L68 HydrophobicContact CG2-CG 4.37Å; I64-L68 VanDerWaalsContact O-CG 3.26Å; I64-L68 WeakPolarHBondContact O-CG 3.28Å; I64-L68 PolarHBondContact O-N 2.63Å; A65-L68 PolarHBondContact O-N 2.73Å; S66-L68 VanDerWaalsContact C-N 3.35Å; S66-L68 PolarHBondContact O-N 3.28Å; L68-K71 PolarHBondContact O-N 2.57Å; L68-Y73 HydrophobicContact CD2-CD1 3.92Å; L68-Y73 HydrophobicContact CD2-CE1 4.3Å; L68-A76 HydrophobicContact CD2-CB 3.87Å; L68-A76 HydrophobicContact CG-CB 4.01Å; L68-I114 HydrophobicContact CB-CG2 4.3Å; L68-L115 HydrophobicContact CD1-CD1 3.39Å; L68-L132 HydrophobicContact CD1-CD2 4.49Å; L68-L132 HydrophobicContact CD2-CD1 4.28Å
69Q87.1Confident86.5Confident63 Ų6337.1 Ų37.129%0.29418%0.178SC..Hα-helixtrans-73.9-33.8175.4-70-63.4-48.600112.5Y22 A65 S66 F67 K71 I114Y22-Q69 HydrophobicContact CD1-CB 3.94Å; Y22-Q69 HydrophobicContact CD1-CG 4.11Å; Y22-Q69 HydrophobicContact CD2-CB 3.74Å; Y22-Q69 HydrophobicContact CD2-CG 4.45Å; Y22-Q69 HydrophobicContact CE1-CB 3.97Å; Y22-Q69 HydrophobicContact CE1-CG 3.69Å; Y22-Q69 HydrophobicContact CE2-CB 3.75Å; Y22-Q69 HydrophobicContact CE2-CG 4.05Å; Y22-Q69 HydrophobicContact CG-CB 3.83Å; Y22-Q69 HydrophobicContact CG-CG 4.47Å; A65-Q69 PolarHBondContact O-N 3.09Å; S66-Q69 PolarHBondContact O-N 3.29Å; F67-Q69 VanDerWaalsContact C-N 3.33Å; F67-Q69 PolarHBondContact O-N 3.08Å; Q69-K71 PolarHBondContact O-N 3.01Å; Q69-I114 HydrophobicContact CG-CD1 4.1Å; Q69-I114 HydrophobicContact CG-CG1 4.08Å; Q69-I114 HydrophobicContact CG-CG2 3.71Å
70L86.8Confident86.3Confident68 Ų6837.1 Ų37.136%0.35618%0.178SC..THydrogen-bonded Turntrans-81.17.5174.3-65.5170.6000113.5E23 L26 S66 F67 N72E23-L70 HydrophobicContact CG-CD1 4.33Å; E23-L70 HydrophobicContact CG-CD2 4.26Å; L26-L70 HydrophobicContact CD1-CD1 3.4Å; L26-L70 HydrophobicContact CG-CD1 4.23Å; S66-L70 WeakPolarHBondContact O-CG 3.39Å; S66-L70 PolarHBondContact O-N 3.37Å; F67-L70 CarbonylContact O-C 3.5Å; F67-L70 PolarHBondContact O-N 3.34Å; L70-N72 PolarHBondContact O-N 3.34Å
71K84.1Confident85.9Confident152 Ų15241.5 Ų41.566%0.66119%0.194SC*.THydrogen-bonded Turntrans58.424.9-179.3-55.4-178.6178.7-179.80114.2F67 L68 Q69 Y73F67-K71 PolarHBondContact O-N 2.72Å; F67-K71 VanDerWaalsContact O-N 3.11Å; L68-K71 PolarHBondContact O-N 2.57Å; Q69-K71 PolarHBondContact O-N 3.01Å; K71-Y73 HydrophobicContact CB-CE2 3.91Å; K71-Y73 VanDerWaalsContact O-CD2 3.25Å; K71-Y73 WeakPolarHBondContact O-CD2 3.2Å; K71-Y73 WeakPolarHBondContact O-CE2 3.31Å; K71-Y73 PolarHBondContact O-N 3.19Å
72N84.1Confident85.5Confident57 Ų5744.9 Ų44.931%0.30521%0.209SC..  trans-96.768.7-179.7-157.913.9000111.3F67 L70 V74 Q75 A76F67-N72 HydrophobicContact CB-CB 4.35Å; F67-N72 HydrophobicContact CD1-CB 3.92Å; F67-N72 HydrophobicContact CG-CB 4.49Å; F67-N72 PolarHBondContact O-N 2.97Å; L70-N72 PolarHBondContact O-N 3.34Å; N72-V74 VanDerWaalsContact C-N 3.33Å; N72-V74 PolarHBondContact O-N 3.08Å; N72-Q75 PolarHBondContact ND2-NE2 3.06Å; N72-Q75 PolarHBondContact ND2-OE1 3.41Å; N72-Q75 VanDerWaalsContact ND2-OE1 3.14Å; N72-Q75 PolarHBondContact OD1-OE1 3.02Å; N72-A76 PolarHBondContact O-N 3.44Å
73Y81.5Confident85Confident52 Ų5245 Ų4520%0.20421%0.211CC..Hα-helixtrans-68.3-26.9-166.6-55.4-72.4000114.5L68 K71 A76 D77 L124L68-Y73 HydrophobicContact CD2-CD1 3.92Å; L68-Y73 HydrophobicContact CD2-CE1 4.3Å; K71-Y73 HydrophobicContact CB-CE2 3.91Å; K71-Y73 VanDerWaalsContact O-CD2 3.25Å; K71-Y73 WeakPolarHBondContact O-CD2 3.2Å; K71-Y73 WeakPolarHBondContact O-CE2 3.31Å; K71-Y73 PolarHBondContact O-N 3.19Å; Y73-A76 PolarHBondContact O-N 3.26Å; Y73-D77 PolarHBondContact O-N 2.81Å; Y73-L124 HydrophobicContact CD1-CD2 4.24Å; Y73-L124 HydrophobicContact CE1-CD2 3.83Å
74V81Confident84.4Confident84 Ų8443.1 Ų43.151%0.50920%0.204SC..Hα-helixtrans-69-47.2-178.5177.60000110.8N72 A76 D77 E78 M127N72-V74 VanDerWaalsContact C-N 3.33Å; N72-V74 PolarHBondContact O-N 3.08Å; V74-A76 VanDerWaalsContact C-N 3.34Å; V74-D77 PolarHBondContact O-N 2.82Å; V74-E78 PolarHBondContact O-N 3.08Å; V74-M127 HydrophobicContact CG2-CE 3.5Å; V74-M127 VanDerWaalsContact CG2-CE 3.5Å
75Q82.9Confident83.5Confident84 Ų8445.1 Ų45.139%0.39323%0.225SC..Hα-helixtrans-68.2-35.5176-73.685.4-2500111.6F67 N72 D77 E78 D79F67-Q75 HydrophobicContact CD1-CB 4.28Å; F67-Q75 HydrophobicContact CD2-CB 3.81Å; F67-Q75 HydrophobicContact CE1-CB 4.19Å; F67-Q75 HydrophobicContact CE2-CB 3.68Å; F67-Q75 HydrophobicContact CG-CB 4.12Å; F67-Q75 HydrophobicContact CZ-CB 3.9Å; F67-Q75 HydrophobicContact CZ-CG 4.31Å; N72-Q75 PolarHBondContact ND2-NE2 3.06Å; N72-Q75 PolarHBondContact ND2-OE1 3.41Å; N72-Q75 VanDerWaalsContact ND2-OE1 3.14Å; N72-Q75 PolarHBondContact OD1-OE1 3.02Å; Q75-D77 VanDerWaalsContact C-N 3.31Å; Q75-D77 PolarHBondContact O-N 3.23Å; Q75-E78 PolarHBondContact O-N 3.48Å; Q75-D79 WeakPolarHBondContact O-CB 3.36Å; Q75-D79 PolarHBondContact O-N 3.15Å; Q75-D79 VanDerWaalsContact O-N 3.09Å
76A84Confident82.1Confident0 Ų048.6 Ų48.60%024%0.241CC..Hα-helixtrans-62-39174.300000112.2I64 F67 L68 N72 Y73 V74 C80I64-A76 HydrophobicContact CG2-CB 4.5Å; F67-A76 HydrophobicContact CB-CB 3.83Å; L68-A76 HydrophobicContact CD2-CB 3.87Å; L68-A76 HydrophobicContact CG-CB 4.01Å; N72-A76 PolarHBondContact O-N 3.44Å; Y73-A76 PolarHBondContact O-N 3.26Å; V74-A76 VanDerWaalsContact C-N 3.34Å; A76-C80 VanDerWaalsContact O-CB 3.29Å; A76-C80 WeakPolarHBondContact O-CB 3.44Å; A76-C80 PolarHBondContact O-N 3.17Å
77D81.4Confident80.5Confident16 Ų1649 Ų499%0.08625%0.245CC..Hα-helixtrans-69.3-45.9175.9175.559.6000113.1Y73 V74 Q75 D79 C80 R81 T129Y73-D77 PolarHBondContact O-N 2.81Å; V74-D77 PolarHBondContact O-N 2.82Å; Q75-D77 VanDerWaalsContact C-N 3.31Å; Q75-D77 PolarHBondContact O-N 3.23Å; D77-D79 VanDerWaalsContact C-N 3.28Å; D77-D79 PolarHBondContact O-N 2.82Å; D77-C80 CarbonylContact O-C 3.6Å; D77-C80 WeakPolarHBondContact O-CA 3.27Å; D77-C80 WeakPolarHBondContact O-CB 3.44Å; D77-C80 PolarHBondContact O-N 2.79Å; D77-R81 PolarHBondContact O-N 2.72Å; D77-R81 IonicContact OD2-CZ 2.7Å; D77-R81 IonicContact OD2-NE 2.66Å; D77-R81 PolarHBondContact OD2-NE 3Å; D77-R81 IonicContact OD2-NH2 3.52Å; D77-R81 PolarHBondContact OD2-NH2 3.44Å; D77-T129 HydrophobicContact CB-CG2 3.97Å; D77-T129 VanDerWaalsContact CG-OG1 3.3Å; D77-T129 WeakPolarHBondContact OD1-CB 3.33Å; D77-T129 WeakPolarHBondContact OD1-CG2 3.47Å; D77-T129 PolarHBondContact OD1-OG1 2.83Å; D77-T129 WeakPolarHBondContact OD2-CG2 3.39Å
78E84Confident78.8Confident101 Ų10150.1 Ų50.147%0.47225%0.252SS..Hα-helixtrans-57.5-44.9178.4-172.264.8-133.300111.1V74 Q75 C80 R81 H82V74-E78 PolarHBondContact O-N 3.08Å; Q75-E78 PolarHBondContact O-N 3.48Å; E78-C80 VanDerWaalsContact C-N 3.31Å; E78-C80 PolarHBondContact O-N 3.04Å; E78-R81 VanDerWaalsContact CD-NH1 3.27Å; E78-R81 PolarHBondContact O-N 2.93Å; E78-R81 IonicContact OE1-CZ 3.54Å; E78-R81 IonicContact OE1-NH1 3.59Å; E78-R81 PolarHBondContact OE1-NH1 3.24Å; E78-R81 VanDerWaalsContact OE1-NH1 3.1Å; E78-R81 IonicContact OE2-CZ 3.12Å; E78-R81 IonicContact OE2-NH1 3.73Å; E78-R81 PolarHBondContact OE2-NH1 2.68Å; E78-R81 IonicContact OE2-NH2 2.78Å; E78-R81 PolarHBondContact OE2-NH2 2.74Å; E78-H82 PolarHBondContact O-N 3.49Å
79D84.4Confident77.2Confident14 Ų1454 Ų548%0.07529%0.285CS..Hα-helixtrans-63.8-37.4175-74.8-10.7000112R63 I64 Q75 D77 H82 V83R63-D79 IonicContact CZ-OD1 2.65Å; R63-D79 IonicContact CZ-OD2 3.68Å; R63-D79 IonicContact NE-OD1 3.1Å; R63-D79 IonicContact NE-OD2 3.9Å; R63-D79 PolarHBondContact NE-OD2 3.38Å; R63-D79 VanDerWaalsContact NH2-CG 3.27Å; R63-D79 IonicContact NH2-OD1 2.89Å; R63-D79 PolarHBondContact NH2-OD1 3.41Å; R63-D79 IonicContact NH2-OD2 3.14Å; R63-D79 PolarHBondContact NH2-OD2 2.74Å; I64-D79 HydrophobicContact CD1-CB 4.03Å; I64-D79 HydrophobicContact CG1-CB 3.51Å; Q75-D79 WeakPolarHBondContact O-CB 3.36Å; Q75-D79 PolarHBondContact O-N 3.15Å; Q75-D79 VanDerWaalsContact O-N 3.09Å; D77-D79 VanDerWaalsContact C-N 3.28Å; D77-D79 PolarHBondContact O-N 2.82Å; D79-H82 PolarHBondContact O-N 2.98Å; D79-V83 VanDerWaalsContact O-CG2 3.3Å; D79-V83 WeakPolarHBondContact O-CG2 3.32Å; D79-V83 PolarHBondContact O-N 3.13Å
80C84.3Confident75.7Confident0 Ų057.3 Ų57.30%030%0.298CS..Hα-helixtrans-64.5-43.9176.7-170.10000111.8I64 A76 D77 E78 H82 V83 L84 D131 L132I64-C80 HydrophobicContact CD1-CB 4.19Å; A76-C80 VanDerWaalsContact O-CB 3.29Å; A76-C80 WeakPolarHBondContact O-CB 3.44Å; A76-C80 PolarHBondContact O-N 3.17Å; D77-C80 CarbonylContact O-C 3.6Å; D77-C80 WeakPolarHBondContact O-CA 3.27Å; D77-C80 WeakPolarHBondContact O-CB 3.44Å; D77-C80 PolarHBondContact O-N 2.79Å; E78-C80 VanDerWaalsContact C-N 3.31Å; E78-C80 PolarHBondContact O-N 3.04Å; C80-H82 VanDerWaalsContact C-N 3.3Å; C80-H82 PolarHBondContact O-N 2.86Å; C80-V83 PolarHBondContact O-N 3.33Å; C80-L84 WeakPolarHBondContact O-CB 3.48Å; C80-L84 WeakPolarHBondContact O-CG 3.36Å; C80-L84 PolarHBondContact O-N 3.3Å; C80-D131 PolarHBondContact SG-O 3.27Å; C80-D131 VanDerWaalsContact SG-O 3.35Å; C80-L132 HydrophobicContact CB-CD2 3.85Å; C80-L132 HydrophobicContact CB-CG 4.27Å
81R82.4Confident74.1Confident97 Ų9755.5 Ų55.537%0.36630%0.296SS..Hα-helixtrans-61.7-38.6173.6-81.5-172.7-78.2113-3.5112.1D77 E78 G85 D131D77-R81 PolarHBondContact O-N 2.72Å; D77-R81 IonicContact OD2-CZ 2.7Å; D77-R81 IonicContact OD2-NE 2.66Å; D77-R81 PolarHBondContact OD2-NE 3Å; D77-R81 IonicContact OD2-NH2 3.52Å; D77-R81 PolarHBondContact OD2-NH2 3.44Å; E78-R81 VanDerWaalsContact CD-NH1 3.27Å; E78-R81 PolarHBondContact O-N 2.93Å; E78-R81 IonicContact OE1-CZ 3.54Å; E78-R81 IonicContact OE1-NH1 3.59Å; E78-R81 PolarHBondContact OE1-NH1 3.24Å; E78-R81 VanDerWaalsContact OE1-NH1 3.1Å; E78-R81 IonicContact OE2-CZ 3.12Å; E78-R81 IonicContact OE2-NH1 3.73Å; E78-R81 PolarHBondContact OE2-NH1 2.68Å; E78-R81 IonicContact OE2-NH2 2.78Å; E78-R81 PolarHBondContact OE2-NH2 2.74Å; R81-G85 WeakPolarHBondContact O-CA 3.47Å; R81-G85 PolarHBondContact O-N 3.29Å; R81-D131 HydrophobicContact CG-CB 4.15Å; R81-D131 WeakPolarHBondContact CG-OD2 3.41Å
82H81.1Confident72.9Confident71 Ų7152.8 Ų52.833%0.32929%0.286SS..Hα-helixtrans-66.6-43.9176.7-171.3-77000112.2E78 D79 C80 E86E78-H82 PolarHBondContact O-N 3.49Å; D79-H82 PolarHBondContact O-N 2.98Å; C80-H82 VanDerWaalsContact C-N 3.3Å; C80-H82 PolarHBondContact O-N 2.86Å; H82-E86 IonicContact CE1-OE1 3.44Å; H82-E86 PolarHBondContact CE1-OE1 2.84Å; H82-E86 IonicContact CE1-OE2 2.94Å; H82-E86 PolarHBondContact CE1-OE2 2.95Å; H82-E86 IonicContact ND1-OE2 3.36Å; H82-E86 IonicContact NE2-OE1 3.35Å; H82-E86 PolarHBondContact NE2-OE1 2.83Å; H82-E86 IonicContact NE2-OE2 3.01Å; H82-E86 WeakPolarHBondContact O-CB 3.44Å; H82-E86 PolarHBondContact O-N 3.45Å
83V82Confident71.8Confident4 Ų456.3 Ų56.32%0.02431%0.305CS..Hα-helixtrans-63.1-47176.7171.60000111.6L60 L61 I64 D79 C80 G87 F95L60-V83 HydrophobicContact CB-CG2 3.33Å; L60-V83 HydrophobicContact CD1-CG2 3.64Å; L60-V83 HydrophobicContact CG-CG2 4.05Å; L61-V83 HydrophobicContact CD2-CG1 4.37Å; I64-V83 HydrophobicContact CD1-CG2 4.13Å; D79-V83 VanDerWaalsContact O-CG2 3.3Å; D79-V83 WeakPolarHBondContact O-CG2 3.32Å; D79-V83 PolarHBondContact O-N 3.13Å; C80-V83 PolarHBondContact O-N 3.33Å; V83-G87 WeakPolarHBondContact O-CA 3.1Å; V83-G87 PolarHBondContact O-N 3.07Å; V83-F95 HydrophobicContact CG1-CD2 4.26Å; V83-F95 HydrophobicContact CG1-CE2 3.29Å; V83-F95 HydrophobicContact CG1-CZ 3.6Å
84L78.4Confident71.1Confident4 Ų455.4 Ų55.42%0.02131%0.308CS..Hα-helixtrans-72.8-37.8-179.7-66.6173.1000111.9C80 L88 F95 D131 R134 L135 L138C80-L84 WeakPolarHBondContact O-CB 3.48Å; C80-L84 WeakPolarHBondContact O-CG 3.36Å; C80-L84 PolarHBondContact O-N 3.3Å; L84-L88 WeakPolarHBondContact O-CB 3.33Å; L84-L88 WeakPolarHBondContact O-CD1 3.42Å; L84-L88 WeakPolarHBondContact O-CG 3.45Å; L84-L88 PolarHBondContact O-N 3.27Å; L84-F95 HydrophobicContact CD2-CE1 4.35Å; L84-D131 HydrophobicContact CD1-CB 3.87Å; L84-D131 WeakPolarHBondContact CD1-O 3.35Å; L84-R134 HydrophobicContact CD1-CB 4.32Å; L84-R134 HydrophobicContact CD1-CG 4.46Å; L84-L135 HydrophobicContact CD2-CD1 4.42Å; L84-L138 HydrophobicContact CD2-CD1 3.73Å
85G69.6Low70.8Confident44 Ų4451.6 Ų51.645%0.45429%0.285SS..Hα-helixtrans-69.6-53-179.600000113.2R81 A89R81-G85 WeakPolarHBondContact O-CA 3.47Å; R81-G85 PolarHBondContact O-N 3.29Å; G85-A89 WeakPolarHBondContact O-CB 3.37Å; G85-A89 PolarHBondContact O-N 2.81Å
86E60.8Low70.5Confident73 Ų7351.3 Ų51.334%0.34128%0.28SS..Hα-helixtrans-71.6-36.6178-71.7-166.9157.100112.4K56 H82 L88 A89 K90K56-E86 WeakPolarHBondContact CE-OE2 3.38Å; K56-E86 VanDerWaalsContact NZ-CD 3.28Å; K56-E86 IonicContact NZ-OE1 3.99Å; K56-E86 PolarHBondContact NZ-OE1 2.82Å; K56-E86 VanDerWaalsContact NZ-OE1 3.08Å; K56-E86 IonicContact NZ-OE2 3.27Å; K56-E86 PolarHBondContact NZ-OE2 3.42Å; H82-E86 IonicContact CE1-OE1 3.44Å; H82-E86 PolarHBondContact CE1-OE1 2.84Å; H82-E86 IonicContact CE1-OE2 2.94Å; H82-E86 PolarHBondContact CE1-OE2 2.95Å; H82-E86 IonicContact ND1-OE2 3.36Å; H82-E86 IonicContact NE2-OE1 3.35Å; H82-E86 PolarHBondContact NE2-OE1 2.83Å; H82-E86 IonicContact NE2-OE2 3.01Å; H82-E86 WeakPolarHBondContact O-CB 3.44Å; H82-E86 PolarHBondContact O-N 3.45Å; E86-L88 VanDerWaalsContact C-N 3.31Å; E86-L88 PolarHBondContact O-N 3.43Å; E86-A89 PolarHBondContact O-N 3.2Å; E86-K90 PolarHBondContact O-N 2.77Å
87G56.9Low70.1Confident9 Ų954.1 Ų54.19%0.09330%0.303CS..Hα-helixtrans-67-28.7179.100000113.7V83V83-G87 WeakPolarHBondContact O-CA 3.1Å; V83-G87 PolarHBondContact O-N 3.07Å
88L53Low70Confident54 Ų5454.1 Ų54.128%0.28330%0.304SS..Hα-helixtrans-88.3-28.5175.7-69.2167.7000113.1L84 E86 E92L84-L88 WeakPolarHBondContact O-CB 3.33Å; L84-L88 WeakPolarHBondContact O-CD1 3.42Å; L84-L88 WeakPolarHBondContact O-CG 3.45Å; L84-L88 PolarHBondContact O-N 3.27Å; E86-L88 VanDerWaalsContact C-N 3.31Å; E86-L88 PolarHBondContact O-N 3.43Å; L88-E92 HydrophobicContact CD2-CB 4.1Å; L88-E92 HydrophobicContact CD2-CG 3.75Å
89A51.5Low70Confident87 Ų8749.4 Ų49.472%0.71928%0.282SS*.Hα-helixtrans-74.2-27.2-179.500000113.6G85 E86G85-A89 WeakPolarHBondContact O-CB 3.37Å; G85-A89 PolarHBondContact O-N 2.81Å; E86-A89 PolarHBondContact O-N 3.2Å
90K54.7Low69.8Low132 Ų13251 Ų5157%0.57429%0.294SS*.THydrogen-bonded Turntrans-94.36.1179-67.7-173.7173.5-177.30114.4E53 E86E53-K90 WeakPolarHBondContact OE1-CD 3.44Å; E53-K90 WeakPolarHBondContact OE1-CE 3.25Å; E53-K90 IonicContact OE1-NZ 3.44Å; E53-K90 PolarHBondContact OE1-NZ 3.08Å; E86-K90 PolarHBondContact O-N 2.77Å
91G54.8Low69.5Low31 Ų3152.9 Ų52.932%0.3231%0.306SS..  trans110.6118-177.600000111D93 A94G91-D93 PolarHBondContact O-N 3Å; G91-A94 PolarHBondContact O-N 2.83Å; G91-A94 VanDerWaalsContact O-N 3.07Å
92E58.4Low69.5Low94 Ų9448.2 Ų48.244%0.43929%0.289SS..Hα-helixtrans-53-24.9179.5-169.6170.6179.600112.7L88 R96L88-E92 HydrophobicContact CD2-CB 4.1Å; L88-E92 HydrophobicContact CD2-CG 3.75Å; E92-R96 WeakPolarHBondContact O-CG 3.42Å; E92-R96 PolarHBondContact O-N 2.83Å; E92-R96 IonicContact OE1-NE 3.93Å; E92-R96 IonicContact OE1-NH2 3.08Å
93D59.9Low69.6Low132 Ų13246.1 Ų46.171%0.70628%0.279SS*.Hα-helixtrans-71.3-34.7-179.8-57.1-36.1000113.8G91 A97G91-D93 PolarHBondContact O-N 3Å; D93-A97 VanDerWaalsContact O-CB 3.29Å; D93-A97 WeakPolarHBondContact O-CB 3.49Å; D93-A97 PolarHBondContact O-N 3.39Å
94A67.1Low69.3Low32 Ų3252.3 Ų52.326%0.26431%0.311SS..Hα-helixtrans-71.8-41.9-178.600000111.6G91 A97 V98G91-A94 PolarHBondContact O-N 2.83Å; G91-A94 VanDerWaalsContact O-N 3.07Å; A94-A97 PolarHBondContact O-N 3.01Å; A94-V98 WeakPolarHBondContact O-CG2 3.33Å; A94-V98 PolarHBondContact O-N 3.11Å; A94-V98 VanDerWaalsContact O-N 3.12Å
95F75.4Confident69.3Low4 Ų457 Ų572%0.01833%0.331CS..Hα-helixtrans-63.8-45.3175.3-179.6-115.7000111.4I57 V83 L84 A97 V98 L99 L135 L138I57-F95 HydrophobicContact CD1-CD2 4.05Å; I57-F95 HydrophobicContact CG1-CD2 4.37Å; I57-F95 HydrophobicContact CG2-CD2 3.95Å; I57-F95 HydrophobicContact CG2-CE2 3.76Å; V83-F95 HydrophobicContact CG1-CD2 4.26Å; V83-F95 HydrophobicContact CG1-CE2 3.29Å; V83-F95 HydrophobicContact CG1-CZ 3.6Å; L84-F95 HydrophobicContact CD2-CE1 4.35Å; F95-A97 PolarHBondContact O-N 3.36Å; F95-V98 PolarHBondContact O-N 3.47Å; F95-L99 HydrophobicContact CD1-CD1 4.15Å; F95-L99 HydrophobicContact CE1-CD1 3.66Å; F95-L99 HydrophobicContact CE1-CG 4.42Å; F95-L99 HydrophobicContact CE2-CD1 4.45Å; F95-L99 HydrophobicContact CE2-CD2 4.44Å; F95-L99 HydrophobicContact CE2-CG 4.4Å; F95-L99 HydrophobicContact CZ-CD1 3.83Å; F95-L99 HydrophobicContact CZ-CD2 4.32Å; F95-L99 HydrophobicContact CZ-CG 4.24Å; F95-L99 WeakPolarHBondContact O-CG 3.3Å; F95-L99 PolarHBondContact O-N 2.89Å; F95-L99 VanDerWaalsContact O-N 3.13Å; F95-L135 HydrophobicContact CZ-CD1 4.11Å; F95-L138 HydrophobicContact CE1-CD1 4.06Å
96R77.4Confident69.7Low79 Ų7956.6 Ų56.630%0.29833%0.327SS..Hα-helixtrans-62.7-40.5175.6-74.2-176179.3-88.23.8112.3E92 V98 L99 C100 E141E92-R96 WeakPolarHBondContact O-CG 3.42Å; E92-R96 PolarHBondContact O-N 2.83Å; E92-R96 IonicContact OE1-NE 3.93Å; E92-R96 IonicContact OE1-NH2 3.08Å; R96-V98 VanDerWaalsContact C-N 3.34Å; R96-V98 PolarHBondContact O-N 2.89Å; R96-L99 PolarHBondContact O-N 3.38Å; R96-C100 PolarHBondContact O-N 3.15Å; R96-C100 PolarHBondContact O-SG 3.17Å; R96-C100 VanDerWaalsContact O-SG 3.34Å; R96-E141 IonicContact CZ-OE2 3.08Å; R96-E141 IonicContact NH1-OE2 2.69Å; R96-E141 PolarHBondContact NH1-OE2 2.86Å; R96-E141 IonicContact NH2-OE2 2.77Å; R96-E141 PolarHBondContact NH2-OE2 3.32Å
97A75.6Confident70.8Confident59 Ų5954.4 Ų54.449%0.48832%0.316SS..Hα-helixtrans-61.3-39.7176.600000112.8D93 A94 F95 C100 C101D93-A97 VanDerWaalsContact O-CB 3.29Å; D93-A97 WeakPolarHBondContact O-CB 3.49Å; D93-A97 PolarHBondContact O-N 3.39Å; A94-A97 PolarHBondContact O-N 3.01Å; F95-A97 PolarHBondContact O-N 3.36Å; A97-C100 PolarHBondContact O-N 3.1Å; A97-C101 WeakPolarHBondContact O-CB 3.19Å; A97-C101 PolarHBondContact O-N 2.85Å
98V79.1Confident72.1Confident16 Ų1654 Ų5410%0.09731%0.312CS..Hα-helixtrans-65.4-43.9175.6173.40000111.1R54 I57 E58 A94 F95 R96 C100 C101 M102R54-V98 HydrophobicContact CB-CG2 4.09Å; R54-V98 HydrophobicContact CG-CG1 4.19Å; R54-V98 HydrophobicContact CG-CG2 4.37Å; I57-V98 HydrophobicContact CB-CG1 4.05Å; I57-V98 HydrophobicContact CD1-CB 4.38Å; I57-V98 HydrophobicContact CD1-CG2 4.11Å; I57-V98 HydrophobicContact CG2-CB 4.45Å; I57-V98 HydrophobicContact CG2-CG1 3.76Å; E58-V98 HydrophobicContact CG-CG1 4.5Å; A94-V98 WeakPolarHBondContact O-CG2 3.33Å; A94-V98 PolarHBondContact O-N 3.11Å; A94-V98 VanDerWaalsContact O-N 3.12Å; F95-V98 PolarHBondContact O-N 3.47Å; R96-V98 VanDerWaalsContact C-N 3.34Å; R96-V98 PolarHBondContact O-N 2.89Å; V98-C100 PolarHBondContact O-N 3.21Å; V98-C101 WeakPolarHBondContact O-CB 3.43Å; V98-C101 PolarHBondContact O-N 2.78Å; V98-M102 HydrophobicContact CG1-CG 4.43Å; V98-M102 HydrophobicContact CG1-SD 4.3Å; V98-M102 WeakPolarHBondContact O-CG 3.3Å; V98-M102 PolarHBondContact O-N 2.86Å
99L83Confident73.7Confident1 Ų155.3 Ų55.31%0.00532%0.317CS..Hα-helixtrans-61.3-42.7176.8-66.1179.1000112.1L61 F95 R96 C101 M102 Q103 L108 L139 T142L61-L99 HydrophobicContact CD1-CD2 3.62Å; F95-L99 HydrophobicContact CD1-CD1 4.15Å; F95-L99 HydrophobicContact CE1-CD1 3.66Å; F95-L99 HydrophobicContact CE1-CG 4.42Å; F95-L99 HydrophobicContact CE2-CD1 4.45Å; F95-L99 HydrophobicContact CE2-CD2 4.44Å; F95-L99 HydrophobicContact CE2-CG 4.4Å; F95-L99 HydrophobicContact CZ-CD1 3.83Å; F95-L99 HydrophobicContact CZ-CD2 4.32Å; F95-L99 HydrophobicContact CZ-CG 4.24Å; F95-L99 WeakPolarHBondContact O-CG 3.3Å; F95-L99 PolarHBondContact O-N 2.89Å; F95-L99 VanDerWaalsContact O-N 3.13Å; R96-L99 PolarHBondContact O-N 3.38Å; L99-C101 PolarHBondContact O-N 3.24Å; L99-M102 HydrophobicContact CD2-SD 4.5Å; L99-M102 PolarHBondContact O-N 3.4Å; L99-Q103 PolarHBondContact O-N 2.91Å; L99-L108 HydrophobicContact CD2-CD1 3.9Å; L99-L139 HydrophobicContact CD1-CD2 4.06Å; L99-L139 HydrophobicContact CD2-CD2 3.56Å; L99-L139 HydrophobicContact CG-CD2 4.41Å; L99-T142 HydrophobicContact CB-CG2 3.89Å
100C79.7Confident75.2Confident49 Ų4952.6 Ų52.633%0.33129%0.291SS..Hα-helixtrans-60.9-43.7174.4-69.60000111.8R96 A97 V98 M102 Q103 L104R96-C100 PolarHBondContact O-N 3.15Å; R96-C100 PolarHBondContact O-SG 3.17Å; R96-C100 VanDerWaalsContact O-SG 3.34Å; A97-C100 PolarHBondContact O-N 3.1Å; V98-C100 PolarHBondContact O-N 3.21Å; C100-M102 PolarHBondContact O-N 2.74Å; C100-Q103 PolarHBondContact O-N 2.77Å; C100-L104 WeakPolarHBondContact O-CG 3.39Å; C100-L104 PolarHBondContact O-N 2.66Å
101C79.7Confident76.7Confident38 Ų3846.4 Ų46.426%0.25727%0.265SS..Hα-helixtrans-62.4-41.1176.5-175.50000112.1A97 V98 L99 K105A97-C101 WeakPolarHBondContact O-CB 3.19Å; A97-C101 PolarHBondContact O-N 2.85Å; V98-C101 WeakPolarHBondContact O-CB 3.43Å; V98-C101 PolarHBondContact O-N 2.78Å; L99-C101 PolarHBondContact O-N 3.24Å; C101-K105 WeakPolarHBondContact O-CB 3.48Å; C101-K105 WeakPolarHBondContact O-CG 3.21Å; C101-K105 PolarHBondContact O-N 3.22Å; C101-K105 VanDerWaalsContact O-N 3.11Å
102M81.9Confident78.2Confident0 Ų045.5 Ų45.50%025%0.253CS..Hα-helixtrans-64.6-38.7174.8-69.6178.677.900112.3E58 L61 Y62 V98 L99 C100 K105 G106 K107 L108E58-M102 HydrophobicContact CB-CE 4.35Å; E58-M102 HydrophobicContact CB-SD 4.47Å; E58-M102 HydrophobicContact CG-CE 3.97Å; E58-M102 HydrophobicContact CG-CG 3.78Å; E58-M102 HydrophobicContact CG-SD 3.67Å; L61-M102 HydrophobicContact CD1-CE 4.04Å; L61-M102 HydrophobicContact CD1-SD 3.68Å; Y62-M102 HydrophobicContact CE1-CE 3.81Å; V98-M102 HydrophobicContact CG1-CG 4.43Å; V98-M102 HydrophobicContact CG1-SD 4.3Å; V98-M102 WeakPolarHBondContact O-CG 3.3Å; V98-M102 PolarHBondContact O-N 2.86Å; L99-M102 HydrophobicContact CD2-SD 4.5Å; L99-M102 PolarHBondContact O-N 3.4Å; C100-M102 PolarHBondContact O-N 2.74Å; M102-K105 PolarHBondContact O-N 3.3Å; M102-G106 PolarHBondContact O-N 3.15Å; M102-K107 HydrophobicContact CB-CB 4.47Å; M102-K107 PolarHBondContact O-N 2.95Å; M102-L108 HydrophobicContact CB-CB 4.05Å; M102-L108 HydrophobicContact CB-CD1 4.07Å; M102-L108 HydrophobicContact CE-CD1 4.07Å; M102-L108 PolarHBondContact O-N 2.88Å; M102-L108 HydrophobicContact SD-CD1 4.06Å
103Q81.7Confident79.6Confident26 Ų2643.9 Ų43.912%0.12125%0.25CS..Hα-helixtrans-67.4-45.9178.3-17962.40.200111.4L99 C100 K105 G106 L108 Q109 T146L99-Q103 PolarHBondContact O-N 2.91Å; C100-Q103 PolarHBondContact O-N 2.77Å; Q103-K105 VanDerWaalsContact C-N 3.25Å; Q103-K105 PolarHBondContact O-N 3.49Å; Q103-G106 PolarHBondContact O-N 3.07Å; Q103-L108 HydrophobicContact CB-CB 4.33Å; Q103-L108 HydrophobicContact CB-CD2 4Å; Q103-Q109 VanDerWaalsContact NE2-NE2 3.15Å; Q103-T146 HydrophobicContact CG-CG2 3.86Å
104L76.4Confident80.8Confident134 Ų13438.2 Ų38.270%0.70222%0.22SC*.Hα-helixtrans-60.5-34.4175.7-71.4172.4000112.6C100 G106 T146C100-L104 WeakPolarHBondContact O-CG 3.39Å; C100-L104 PolarHBondContact O-N 2.66Å; L104-G106 VanDerWaalsContact C-N 3.27Å; L104-G106 PolarHBondContact O-N 2.98Å; L104-T146 HydrophobicContact CD2-CG2 3.87Å; L104-T146 HydrophobicContact CG-CG2 4.31Å
105K77.9Confident81.6Confident104 Ų10436.8 Ų36.845%0.45221%0.208SC..THydrogen-bonded Turntrans-832.6175.7-67179.1-179.5-179.80113.7C101 M102 Q103 K107C101-K105 WeakPolarHBondContact O-CB 3.48Å; C101-K105 WeakPolarHBondContact O-CG 3.21Å; C101-K105 PolarHBondContact O-N 3.22Å; C101-K105 VanDerWaalsContact O-N 3.11Å; M102-K105 PolarHBondContact O-N 3.3Å; Q103-K105 VanDerWaalsContact C-N 3.25Å; Q103-K105 PolarHBondContact O-N 3.49Å; K105-K107 HydrophobicContact CB-CD 4.31Å; K105-K107 HydrophobicContact CB-CG 4.03Å; K105-K107 PolarHBondContact O-N 3.44Å
106G79.4Confident82Confident35 Ų3538.1 Ų38.136%0.36122%0.22SC..THydrogen-bonded Turntrans62.921.2-177.700000114M102 Q103 L104M102-G106 PolarHBondContact O-N 3.15Å; Q103-G106 PolarHBondContact O-N 3.07Å; L104-G106 VanDerWaalsContact C-N 3.27Å; L104-G106 PolarHBondContact O-N 2.98Å
107K82.3Confident82.2Confident27 Ų2741 Ų4112%0.11723%0.234CC..  trans-91.3-17.2-178.3-66-171.3178.6-1720112.8E11 Y62 M102 K105 P110E11-K107 IonicContact OE1-NZ 3.51Å; E11-K107 PolarHBondContact OE1-NZ 3.23Å; Y62-K107 WeakPolarHBondContact OH-CB 3.42Å; M102-K107 HydrophobicContact CB-CB 4.47Å; M102-K107 PolarHBondContact O-N 2.95Å; K105-K107 HydrophobicContact CB-CD 4.31Å; K105-K107 HydrophobicContact CB-CG 4.03Å; K105-K107 PolarHBondContact O-N 3.44Å; K107-P110 WeakPolarHBondContact O-CD 3.27Å
108L85.5Confident82.3Confident0 Ų039 Ų390%022%0.217CC..SBendtrans-83-30.3-177.7-161.669.9000114L99 M102 Q103 V111 S112 L139 T142 E143L99-L108 HydrophobicContact CD2-CD1 3.9Å; M102-L108 HydrophobicContact CB-CB 4.05Å; M102-L108 HydrophobicContact CB-CD1 4.07Å; M102-L108 HydrophobicContact CE-CD1 4.07Å; M102-L108 PolarHBondContact O-N 2.88Å; M102-L108 HydrophobicContact SD-CD1 4.06Å; Q103-L108 HydrophobicContact CB-CB 4.33Å; Q103-L108 HydrophobicContact CB-CD2 4Å; L108-V111 WeakPolarHBondContact O-CB 3.5Å; L108-V111 PolarHBondContact O-N 3Å; L108-V111 VanDerWaalsContact O-N 3.1Å; L108-S112 PolarHBondContact O-N 3.02Å; L108-L139 HydrophobicContact CD1-CD2 3.8Å; L108-L139 HydrophobicContact CD2-CD2 4.21Å; L108-L139 HydrophobicContact CG-CD2 4.29Å; L108-T142 HydrophobicContact CD2-CG2 4.43Å; L108-E143 HydrophobicContact CD2-CG 4.32Å
109Q85.3Confident82Confident82 Ų8240 Ų4038%0.38322%0.221SC..Hα-helixtrans-54.3-44.2-176.6-69.8-61.1-55.600114.9Q103 V111 S112 T113 E143Q103-Q109 VanDerWaalsContact NE2-NE2 3.15Å; Q109-V111 VanDerWaalsContact C-N 3.31Å; Q109-V111 PolarHBondContact O-N 2.91Å; Q109-S112 PolarHBondContact O-N 2.87Å; Q109-T113 WeakPolarHBondContact O-CB 3.45Å; Q109-T113 PolarHBondContact O-N 2.88Å; Q109-T113 PolarHBondContact O-OG1 2.98Å; Q109-E143 PolarHBondContact NE2-OE1 2.67Å
110P84.3Confident81.3Confident29 Ų2944.9 Ų44.919%0.18825%0.251CS..Hα-helixtrans-62.2-38.8177.5-22.434.5000112.6L17 K18 K107 I114L17-P110 HydrophobicContact CD2-CB 4.23Å; L17-P110 HydrophobicContact CG-CB 4.44Å; K18-P110 HydrophobicContact CG-CG 4.02Å; K107-P110 WeakPolarHBondContact O-CD 3.27Å; P110-I114 WeakPolarHBondContact O-CB 3.41Å; P110-I114 WeakPolarHBondContact O-CD1 3.4Å; P110-I114 VanDerWaalsContact O-CG1 3.25Å; P110-I114 WeakPolarHBondContact O-CG1 3.25Å; P110-I114 PolarHBondContact O-N 3.38Å; P110-I114 VanDerWaalsContact O-N 3.08Å
111V86.7Confident80.3Confident3 Ų344.5 Ų44.52%0.01826%0.255CS..Hα-helixtrans-68.9-48.3179.7179.20000110.4L17 L61 Y62 A65 L108 Q109 T113 I114 L115 L139L17-V111 HydrophobicContact CD2-CG2 3.94Å; L61-V111 HydrophobicContact CB-CG1 4.33Å; Y62-V111 HydrophobicContact CD1-CG2 3.63Å; Y62-V111 HydrophobicContact CE1-CG2 3.96Å; A65-V111 HydrophobicContact CB-CG1 4.29Å; A65-V111 HydrophobicContact CB-CG2 4.29Å; L108-V111 WeakPolarHBondContact O-CB 3.5Å; L108-V111 PolarHBondContact O-N 3Å; L108-V111 VanDerWaalsContact O-N 3.1Å; Q109-V111 VanDerWaalsContact C-N 3.31Å; Q109-V111 PolarHBondContact O-N 2.91Å; V111-T113 PolarHBondContact O-N 3.05Å; V111-I114 PolarHBondContact O-N 3.19Å; V111-L115 VanDerWaalsContact O-CB 3.25Å; V111-L115 WeakPolarHBondContact O-CB 3.27Å; V111-L115 PolarHBondContact O-N 2.93Å; V111-L139 HydrophobicContact CG1-CD1 4Å
112S86.6Confident78.9Confident11 Ų1152.6 Ų52.68%0.07729%0.29CS..Hα-helixtrans-60.7-43.7178.4-173.60000111.7L108 Q109 I114 L115 A116 E143L108-S112 PolarHBondContact O-N 3.02Å; Q109-S112 PolarHBondContact O-N 2.87Å; S112-I114 PolarHBondContact O-N 3.3Å; S112-L115 PolarHBondContact O-N 2.84Å; S112-A116 VanDerWaalsContact O-CB 3.26Å; S112-A116 WeakPolarHBondContact O-CB 3.47Å; S112-A116 PolarHBondContact O-N 2.93Å; S112-E143 WeakPolarHBondContact CB-OE1 3.35Å; S112-E143 VanDerWaalsContact OG-CD 3.25Å; S112-E143 PolarHBondContact OG-OE1 2.75Å; S112-E143 VanDerWaalsContact OG-OE1 3.11Å; S112-E143 PolarHBondContact OG-OE2 3.19Å
113T85.9Confident77.4Confident60 Ų6056.1 Ų56.137%0.36831%0.314SS..Hα-helixtrans-63-45.1178.5-58.40000112.1Q109 V111 K117Q109-T113 WeakPolarHBondContact O-CB 3.45Å; Q109-T113 PolarHBondContact O-N 2.88Å; Q109-T113 PolarHBondContact O-OG1 2.98Å; V111-T113 PolarHBondContact O-N 3.05Å; T113-K117 HydrophobicContact CG2-CD 4.12Å; T113-K117 WeakPolarHBondContact O-CB 3.43Å; T113-K117 VanDerWaalsContact O-CG 3.29Å; T113-K117 WeakPolarHBondContact O-CG 3.28Å; T113-K117 PolarHBondContact O-N 3.33Å
114I85.1Confident76.1Confident13 Ų1357.1 Ų57.17%0.06732%0.32CS..Hα-helixtrans-64-47.3177.9-77.4167.8000110.6L17 Y22 A65 L68 Q69 P110 V111 S112 A116 K117 S118L17-I114 HydrophobicContact CD1-CD1 3.78Å; L17-I114 HydrophobicContact CG-CD1 4.26Å; Y22-I114 HydrophobicContact CE1-CD1 3.99Å; A65-I114 HydrophobicContact CB-CB 4.31Å; A65-I114 HydrophobicContact CB-CD1 4.13Å; A65-I114 HydrophobicContact CB-CG2 3.88Å; A65-I114 WeakPolarHBondContact O-CG2 3.3Å; L68-I114 HydrophobicContact CB-CG2 4.3Å; Q69-I114 HydrophobicContact CG-CD1 4.1Å; Q69-I114 HydrophobicContact CG-CG1 4.08Å; Q69-I114 HydrophobicContact CG-CG2 3.71Å; P110-I114 WeakPolarHBondContact O-CB 3.41Å; P110-I114 WeakPolarHBondContact O-CD1 3.4Å; P110-I114 VanDerWaalsContact O-CG1 3.25Å; P110-I114 WeakPolarHBondContact O-CG1 3.25Å; P110-I114 PolarHBondContact O-N 3.38Å; P110-I114 VanDerWaalsContact O-N 3.08Å; V111-I114 PolarHBondContact O-N 3.19Å; S112-I114 PolarHBondContact O-N 3.3Å; I114-A116 PolarHBondContact O-N 3.15Å; I114-K117 PolarHBondContact O-N 3.12Å; I114-S118 WeakPolarHBondContact O-CB 3.41Å; I114-S118 PolarHBondContact O-N 2.87Å; I114-S118 PolarHBondContact O-OG 2.85Å; I114-S118 VanDerWaalsContact O-OG 3.11Å
115L84.4Confident74.9Confident3 Ų358 Ų582%0.01633%0.325CS..Hα-helixtrans-62.1-43.3179.4-168.372.1000111.4L68 V111 S112 L119 L132 L135 K136 L139L68-L115 HydrophobicContact CD1-CD1 3.39Å; V111-L115 VanDerWaalsContact O-CB 3.25Å; V111-L115 WeakPolarHBondContact O-CB 3.27Å; V111-L115 PolarHBondContact O-N 2.93Å; S112-L115 PolarHBondContact O-N 2.84Å; L115-L119 HydrophobicContact CD1-CD1 4.25Å; L115-L119 HydrophobicContact CG-CD1 3.97Å; L115-L119 WeakPolarHBondContact O-CB 3.46Å; L115-L119 WeakPolarHBondContact O-CD1 3.38Å; L115-L119 WeakPolarHBondContact O-CG 3.41Å; L115-L119 PolarHBondContact O-N 2.84Å; L115-L119 VanDerWaalsContact O-N 3.12Å; L115-L132 HydrophobicContact CD1-CD2 4.14Å; L115-L135 HydrophobicContact CD2-CD2 4.49Å; L115-L135 HydrophobicContact CD2-CG 4.22Å; L115-K136 VanDerWaalsContact CD2-CA 3.49Å; L115-K136 HydrophobicContact CD2-CB 3.74Å; L115-K136 HydrophobicContact CD2-CG 4.39Å; L115-K136 HydrophobicContact CG-CB 4.25Å; L115-L139 HydrophobicContact CD2-CD1 3.82Å
116A83.8Confident73.7Confident32 Ų3257 Ų5726%0.26434%0.344SS..Hα-helixtrans-62.8-47.617700000111.9S112 I114 L119 T120S112-A116 VanDerWaalsContact O-CB 3.26Å; S112-A116 WeakPolarHBondContact O-CB 3.47Å; S112-A116 PolarHBondContact O-N 2.93Å; I114-A116 PolarHBondContact O-N 3.15Å; A116-L119 PolarHBondContact O-N 2.93Å; A116-T120 WeakPolarHBondContact O-CG2 3.44Å; A116-T120 PolarHBondContact O-N 3.5Å; A116-T120 PolarHBondContact O-OG1 2.91Å; A116-T120 VanDerWaalsContact O-OG1 3.11Å
117K82.4Confident72.5Confident139 Ų13961.2 Ų61.260%0.60436%0.356SS*.Hα-helixtrans-63.1-44.6178.9-75.6177179.7-179.70112.5T113 I114 L119 T120 G121T113-K117 HydrophobicContact CG2-CD 4.12Å; T113-K117 WeakPolarHBondContact O-CB 3.43Å; T113-K117 VanDerWaalsContact O-CG 3.29Å; T113-K117 WeakPolarHBondContact O-CG 3.28Å; T113-K117 PolarHBondContact O-N 3.33Å; I114-K117 PolarHBondContact O-N 3.12Å; K117-L119 PolarHBondContact O-N 3.43Å; K117-T120 PolarHBondContact O-N 2.76Å; K117-T120 PolarHBondContact O-OG1 3.16Å; K117-T120 VanDerWaalsContact O-OG1 3.07Å; K117-G121 PolarHBondContact O-N 2.74Å
118S76.9Confident71.1Confident17 Ų1761.9 Ų61.912%0.11936%0.362CS..Hα-helixtrans-65.1-28.2178.8-66.80000112.4I114 L124I114-S118 WeakPolarHBondContact O-CB 3.41Å; I114-S118 PolarHBondContact O-N 2.87Å; I114-S118 PolarHBondContact O-OG 2.85Å; I114-S118 VanDerWaalsContact O-OG 3.11Å; S118-L124 VanDerWaalsContact O-CD1 3.3Å; S118-L124 WeakPolarHBondContact O-CD1 3.39Å
119L73.9Confident70.2Confident36 Ų3663.5 Ų63.519%0.18837%0.372CS..Hα-helixtrans-88.6-9.7178.7-69.7169.4000114.7L115 A116 K117 L124 V128 K136L115-L119 HydrophobicContact CD1-CD1 4.25Å; L115-L119 HydrophobicContact CG-CD1 3.97Å; L115-L119 WeakPolarHBondContact O-CB 3.46Å; L115-L119 WeakPolarHBondContact O-CD1 3.38Å; L115-L119 WeakPolarHBondContact O-CG 3.41Å; L115-L119 PolarHBondContact O-N 2.84Å; L115-L119 VanDerWaalsContact O-N 3.12Å; A116-L119 PolarHBondContact O-N 2.93Å; K117-L119 PolarHBondContact O-N 3.43Å; L119-L124 HydrophobicContact CD2-CD1 3.92Å; L119-V128 HydrophobicContact CD2-CG1 3.43Å; L119-V128 VanDerWaalsContact CD2-CG1 3.43Å; L119-K136 HydrophobicContact CB-CD 4.46Å; L119-K136 HydrophobicContact CD1-CB 3.86Å; L119-K136 HydrophobicContact CD1-CD 3.6Å; L119-K136 HydrophobicContact CD1-CG 4.21Å
120T68.2Low69.4Low105 Ų10568 Ų6864%0.64439%0.391SS*.Hα-helixtrans-102.7-8.7178.850.80000114.3A116 K117A116-T120 WeakPolarHBondContact O-CG2 3.44Å; A116-T120 PolarHBondContact O-N 3.5Å; A116-T120 PolarHBondContact O-OG1 2.91Å; A116-T120 VanDerWaalsContact O-OG1 3.11Å; K117-T120 PolarHBondContact O-N 2.76Å; K117-T120 PolarHBondContact O-OG1 3.16Å; K117-T120 VanDerWaalsContact O-OG1 3.07Å
121G58.1Low69.1Low40 Ų4068.4 Ų68.441%0.41239%0.391SS..SBendtrans-85.5145.8-179.600000113.6K117 S123K117-G121 PolarHBondContact O-N 2.74Å; G121-S123 PolarHBondContact O-N 3.32Å
122E49.5Very low68.8Low209 Ų20968.4 Ų68.498%0.97739%0.391SS*.SBendtrans-64.510.1-175.8-68.4-175.6147.800116.4
123S51.7Low68.5Low73 Ų7371.3 Ų71.351%0.5141%0.408SS..  trans-118.737.4-175.283.10000114.7G121G121-S123 PolarHBondContact O-N 3.32Å
124L54.7Low68.4Low47 Ų4773.6 Ų73.625%0.24641%0.41CS..  trans-101.279.3168.8-62.1177.7000108.6Y73 S118 L119 G126 V128Y73-L124 HydrophobicContact CD1-CD2 4.24Å; Y73-L124 HydrophobicContact CE1-CD2 3.83Å; S118-L124 VanDerWaalsContact O-CD1 3.3Å; S118-L124 WeakPolarHBondContact O-CD1 3.39Å; L119-L124 HydrophobicContact CD2-CD1 3.92Å; L124-G126 PolarHBondContact O-N 3.26Å; L124-V128 HydrophobicContact CB-CB 4.45Å; L124-V128 HydrophobicContact CB-CG2 3.81Å; L124-V128 HydrophobicContact CD1-CB 4.18Å; L124-V128 HydrophobicContact CD1-CG1 4.43Å; L124-V128 HydrophobicContact CD1-CG2 3.56Å; L124-V128 HydrophobicContact CD2-CG2 3.4Å; L124-V128 VanDerWaalsContact CD2-CG2 3.4Å; L124-V128 HydrophobicContact CG-CG2 3.73Å
125N49.9Very low68.4Low152 Ų15273 Ų7381%0.81341%0.407SS*.  trans-62.473.9177-85.9-15.1000111.5M127N125-M127 PolarHBondContact O-N 2.83Å
126G52.7Low68.4Low83 Ų8375.8 Ų75.886%0.85642%0.419SS*.SBendtrans61.62.2167.100000117L124L124-G126 PolarHBondContact O-N 3.26Å
127M53.8Low68.3Low125 Ų12577.5 Ų77.562%0.61643%0.427SS*.  trans-108.58.3-173.3-105174.667.500114V74 N125 T129V74-M127 HydrophobicContact CG2-CE 3.5Å; V74-M127 VanDerWaalsContact CG2-CE 3.5Å; N125-M127 PolarHBondContact O-N 2.83Å; M127-T129 PolarHBondContact O-N 2.79Å
128V53.8Low68.3Low40 Ų4071.7 Ų71.724%0.24240%0.402CS..  trans-85.8115.8172.5172.30000110L119 L124 L132L119-V128 HydrophobicContact CD2-CG1 3.43Å; L119-V128 VanDerWaalsContact CD2-CG1 3.43Å; L124-V128 HydrophobicContact CB-CB 4.45Å; L124-V128 HydrophobicContact CB-CG2 3.81Å; L124-V128 HydrophobicContact CD1-CB 4.18Å; L124-V128 HydrophobicContact CD1-CG1 4.43Å; L124-V128 HydrophobicContact CD1-CG2 3.56Å; L124-V128 HydrophobicContact CD2-CG2 3.4Å; L124-V128 VanDerWaalsContact CD2-CG2 3.4Å; L124-V128 HydrophobicContact CG-CG2 3.73Å; V128-L132 HydrophobicContact CG1-CB 4.18Å; V128-L132 HydrophobicContact CG1-CD1 4.26Å
129T66.6Low68.7Low34 Ų3470.9 Ų70.921%0.20940%0.397CS..  trans-73.4146.1-172.554.80000111.6D77 M127 D131 L132 T133D77-T129 HydrophobicContact CB-CG2 3.97Å; D77-T129 VanDerWaalsContact CG-OG1 3.3Å; D77-T129 WeakPolarHBondContact OD1-CB 3.33Å; D77-T129 WeakPolarHBondContact OD1-CG2 3.47Å; D77-T129 PolarHBondContact OD1-OG1 2.83Å; D77-T129 WeakPolarHBondContact OD2-CG2 3.39Å; M127-T129 PolarHBondContact O-N 2.79Å; T129-D131 PolarHBondContact O-N 3.08Å; T129-L132 PolarHBondContact O-N 3.44Å; T129-L132 VanDerWaalsContact O-N 3.13Å; T129-T133 PolarHBondContact O-N 3.48Å
130K69.1Low69.1Low178 Ų17871.4 Ų71.477%0.77440%0.403SS*.Hα-helixtrans-41.8-31.5168.5-178.2-179.5174-176.50112.5R134K130-R134 VanDerWaalsContact O-CB 3.32Å; K130-R134 WeakPolarHBondContact O-CB 3.18Å; K130-R134 PolarHBondContact O-N 3.22Å
131D77.8Confident69.8Low37 Ų3770.1 Ų70.120%0.19839%0.39CS..Hα-helixtrans-73.3-45.4-176.7-62.6-45.2000113.4C80 R81 L84 T129 T133 R134 L135C80-D131 PolarHBondContact SG-O 3.27Å; C80-D131 VanDerWaalsContact SG-O 3.35Å; R81-D131 HydrophobicContact CG-CB 4.15Å; R81-D131 WeakPolarHBondContact CG-OD2 3.41Å; L84-D131 HydrophobicContact CD1-CB 3.87Å; L84-D131 WeakPolarHBondContact CD1-O 3.35Å; T129-D131 PolarHBondContact O-N 3.08Å; D131-T133 VanDerWaalsContact C-N 3.27Å; D131-T133 PolarHBondContact O-N 2.87Å; D131-R134 WeakPolarHBondContact O-CB 3.29Å; D131-R134 PolarHBondContact O-N 2.65Å; D131-L135 PolarHBondContact O-N 3.1Å
132L80.4Confident70.8Confident2 Ų268.5 Ų68.51%0.0137%0.372CS..Hα-helixtrans-63.5-35175.5-74.6170.1000112.3I64 L68 C80 L115 V128 T129 K136I64-L132 HydrophobicContact CG2-CD2 4.02Å; L68-L132 HydrophobicContact CD1-CD2 4.49Å; L68-L132 HydrophobicContact CD2-CD1 4.28Å; C80-L132 HydrophobicContact CB-CD2 3.85Å; C80-L132 HydrophobicContact CB-CG 4.27Å; L115-L132 HydrophobicContact CD1-CD2 4.14Å; V128-L132 HydrophobicContact CG1-CB 4.18Å; V128-L132 HydrophobicContact CG1-CD1 4.26Å; T129-L132 PolarHBondContact O-N 3.44Å; T129-L132 VanDerWaalsContact O-N 3.13Å; L132-K136 PolarHBondContact O-N 2.96Å
133T80.7Confident72.2Confident72 Ų7259.9 Ų59.944%0.44233%0.331SS..Hα-helixtrans-69.1-43.1175.4-53.70000110.6T129 D131 L135 K136 T137T129-T133 PolarHBondContact O-N 3.48Å; D131-T133 VanDerWaalsContact C-N 3.27Å; D131-T133 PolarHBondContact O-N 2.87Å; T133-L135 PolarHBondContact O-N 2.95Å; T133-K136 WeakPolarHBondContact O-CB 3.12Å; T133-K136 PolarHBondContact O-N 2.79Å; T133-T137 PolarHBondContact O-N 2.89Å; T133-T137 PolarHBondContact O-OG1 2.85Å; T133-T137 VanDerWaalsContact O-OG1 3.12Å
134R81.9Confident73.3Confident109 Ų10960.1 Ų60.141%0.41133%0.33SS..Hα-helixtrans-61.5-42.3175.1-174.7177.5-178.1-167.81.5111.9L84 K130 D131 T137 L138L84-R134 HydrophobicContact CD1-CB 4.32Å; L84-R134 HydrophobicContact CD1-CG 4.46Å; K130-R134 VanDerWaalsContact O-CB 3.32Å; K130-R134 WeakPolarHBondContact O-CB 3.18Å; K130-R134 PolarHBondContact O-N 3.22Å; D131-R134 WeakPolarHBondContact O-CB 3.29Å; D131-R134 PolarHBondContact O-N 2.65Å; R134-T137 PolarHBondContact O-N 3.2Å; R134-L138 HydrophobicContact CG-CD1 4.43Å; R134-L138 WeakPolarHBondContact O-CG 3.34Å; R134-L138 PolarHBondContact O-N 3.04Å
135L85.1Confident74Confident1 Ų160.7 Ų60.71%0.00534%0.341CS..Hα-helixtrans-61.5-43.6175.3-177.162000111.1L61 I64 L84 F95 L115 D131 T133 T137 L138 L139L61-L135 HydrophobicContact CD2-CD1 3.99Å; L61-L135 HydrophobicContact CD2-CD2 3.98Å; I64-L135 HydrophobicContact CD1-CD2 4.13Å; L84-L135 HydrophobicContact CD2-CD1 4.42Å; F95-L135 HydrophobicContact CZ-CD1 4.11Å; L115-L135 HydrophobicContact CD2-CD2 4.49Å; L115-L135 HydrophobicContact CD2-CG 4.22Å; D131-L135 PolarHBondContact O-N 3.1Å; T133-L135 PolarHBondContact O-N 2.95Å; L135-T137 VanDerWaalsContact C-N 3.32Å; L135-T137 PolarHBondContact O-N 2.71Å; L135-L138 PolarHBondContact O-N 2.94Å; L135-L139 HydrophobicContact CD1-CD2 4.45Å; L135-L139 HydrophobicContact CD1-CG 4.39Å; L135-L139 HydrophobicContact CG-CG 4.46Å; L135-L139 WeakPolarHBondContact O-CG 3.49Å; L135-L139 PolarHBondContact O-N 3.33Å
136K84.7Confident74.5Confident60 Ų6054.6 Ų54.626%0.26131%0.31SS..Hα-helixtrans-57.7-44.9175.7-177.3-173.4178.4174.60112L115 L119 L132 T133 L139 S140L115-K136 VanDerWaalsContact CD2-CA 3.49Å; L115-K136 HydrophobicContact CD2-CB 3.74Å; L115-K136 HydrophobicContact CD2-CG 4.39Å; L115-K136 HydrophobicContact CG-CB 4.25Å; L119-K136 HydrophobicContact CB-CD 4.46Å; L119-K136 HydrophobicContact CD1-CB 3.86Å; L119-K136 HydrophobicContact CD1-CD 3.6Å; L119-K136 HydrophobicContact CD1-CG 4.21Å; L132-K136 PolarHBondContact O-N 2.96Å; T133-K136 WeakPolarHBondContact O-CB 3.12Å; T133-K136 PolarHBondContact O-N 2.79Å; K136-L139 PolarHBondContact O-N 2.96Å; K136-S140 WeakPolarHBondContact O-CB 3.4Å; K136-S140 PolarHBondContact O-N 3.35Å; K136-S140 PolarHBondContact O-OG 2.9Å
137T82.7Confident74.6Confident69 Ų6953.8 Ų53.842%0.42329%0.291SS..Hα-helixtrans-60.6-46.2177.6-52.50000110.8T133 R134 L135 L139 S140 E141T133-T137 PolarHBondContact O-N 2.89Å; T133-T137 PolarHBondContact O-OG1 2.85Å; T133-T137 VanDerWaalsContact O-OG1 3.12Å; R134-T137 PolarHBondContact O-N 3.2Å; L135-T137 VanDerWaalsContact C-N 3.32Å; L135-T137 PolarHBondContact O-N 2.71Å; T137-L139 PolarHBondContact O-N 3.31Å; T137-S140 PolarHBondContact O-N 3.01Å; T137-E141 HydrophobicContact CG2-CG 4.47Å; T137-E141 WeakPolarHBondContact CG2-OE1 3.19Å; T137-E141 WeakPolarHBondContact O-CB 3.31Å; T137-E141 WeakPolarHBondContact O-CG 3.37Å; T137-E141 PolarHBondContact O-N 3.21Å
138L82.8Confident74.2Confident17 Ų1753.5 Ų53.59%0.08929%0.292CS..Hα-helixtrans-63.7-39.4178.7-70171.7000113.2L84 F95 R134 L135 T142L84-L138 HydrophobicContact CD2-CD1 3.73Å; F95-L138 HydrophobicContact CE1-CD1 4.06Å; R134-L138 HydrophobicContact CG-CD1 4.43Å; R134-L138 WeakPolarHBondContact O-CG 3.34Å; R134-L138 PolarHBondContact O-N 3.04Å; L135-L138 PolarHBondContact O-N 2.94Å; L138-T142 WeakPolarHBondContact O-CB 3.42Å; L138-T142 PolarHBondContact O-N 2.83Å; L138-T142 PolarHBondContact O-OG1 2.78Å
139L84.7Confident73.8Confident0 Ų055.6 Ų55.60%031%0.314CS..Hα-helixtrans-65.1-43.4175.1-64.6-168000111.1L99 L108 V111 L115 L135 K136 T137 T142 E143L99-L139 HydrophobicContact CD1-CD2 4.06Å; L99-L139 HydrophobicContact CD2-CD2 3.56Å; L99-L139 HydrophobicContact CG-CD2 4.41Å; L108-L139 HydrophobicContact CD1-CD2 3.8Å; L108-L139 HydrophobicContact CD2-CD2 4.21Å; L108-L139 HydrophobicContact CG-CD2 4.29Å; V111-L139 HydrophobicContact CG1-CD1 4Å; L115-L139 HydrophobicContact CD2-CD1 3.82Å; L135-L139 HydrophobicContact CD1-CD2 4.45Å; L135-L139 HydrophobicContact CD1-CG 4.39Å; L135-L139 HydrophobicContact CG-CG 4.46Å; L135-L139 WeakPolarHBondContact O-CG 3.49Å; L135-L139 PolarHBondContact O-N 3.33Å; K136-L139 PolarHBondContact O-N 2.96Å; T137-L139 PolarHBondContact O-N 3.31Å; L139-T142 PolarHBondContact O-N 3.43Å; L139-E143 VanDerWaalsContact O-CG 3.29Å; L139-E143 WeakPolarHBondContact O-CG 3.35Å; L139-E143 PolarHBondContact O-N 3.34Å
140S83Confident72.7Confident46 Ų4661.6 Ų61.632%0.32234%0.344SS..Hα-helixtrans-65.9-40.8178.8-530000112K136 T137 T142 E143 T144K136-S140 WeakPolarHBondContact O-CB 3.4Å; K136-S140 PolarHBondContact O-N 3.35Å; K136-S140 PolarHBondContact O-OG 2.9Å; T137-S140 PolarHBondContact O-N 3.01Å; S140-T142 VanDerWaalsContact C-N 3.31Å; S140-T142 PolarHBondContact O-N 3.47Å; S140-E143 PolarHBondContact O-N 3.5Å; S140-T144 WeakPolarHBondContact O-CB 3.44Å; S140-T144 WeakPolarHBondContact O-CG2 3.4Å; S140-T144 PolarHBondContact O-N 3.31Å; S140-T144 PolarHBondContact O-OG1 3.5Å
141E81.9Confident71Confident79 Ų7957.6 Ų57.637%0.36934%0.338SS..Hα-helixtrans-60-41.2172-76.9174-168.100111.4R96 T137 T144 A145R96-E141 IonicContact CZ-OE2 3.08Å; R96-E141 IonicContact NH1-OE2 2.69Å; R96-E141 PolarHBondContact NH1-OE2 2.86Å; R96-E141 IonicContact NH2-OE2 2.77Å; R96-E141 PolarHBondContact NH2-OE2 3.32Å; T137-E141 HydrophobicContact CG2-CG 4.47Å; T137-E141 WeakPolarHBondContact CG2-OE1 3.19Å; T137-E141 WeakPolarHBondContact O-CB 3.31Å; T137-E141 WeakPolarHBondContact O-CG 3.37Å; T137-E141 PolarHBondContact O-N 3.21Å; E141-T144 WeakPolarHBondContact CA-OG1 3.22Å; E141-T144 PolarHBondContact O-OG1 3.37Å; E141-A145 WeakPolarHBondContact O-CB 3.24Å; E141-A145 PolarHBondContact O-N 2.97Å
142T80.5Confident68.8Low5 Ų558.7 Ų58.73%0.03136%0.358CS..Hα-helixtrans-71-39.8-180-53.20000111.7L99 L108 L138 L139 S140 T146L99-T142 HydrophobicContact CB-CG2 3.89Å; L108-T142 HydrophobicContact CD2-CG2 4.43Å; L138-T142 WeakPolarHBondContact O-CB 3.42Å; L138-T142 PolarHBondContact O-N 2.83Å; L138-T142 PolarHBondContact O-OG1 2.78Å; L139-T142 PolarHBondContact O-N 3.43Å; S140-T142 VanDerWaalsContact C-N 3.31Å; S140-T142 PolarHBondContact O-N 3.47Å; T142-T146 WeakPolarHBondContact O-CB 3.35Å; T142-T146 PolarHBondContact O-N 3.42Å; T142-T146 PolarHBondContact O-OG1 2.78Å
143E77.1Confident66.3Low28 Ų2869.2 Ų69.213%0.13140%0.399CS..Hα-helixtrans-64.6-41176.1-72.1176.6147.100111.7L108 Q109 S112 L139 S140 S147L108-E143 HydrophobicContact CD2-CG 4.32Å; Q109-E143 PolarHBondContact NE2-OE1 2.67Å; S112-E143 WeakPolarHBondContact CB-OE1 3.35Å; S112-E143 VanDerWaalsContact OG-CD 3.25Å; S112-E143 PolarHBondContact OG-OE1 2.75Å; S112-E143 VanDerWaalsContact OG-OE1 3.11Å; S112-E143 PolarHBondContact OG-OE2 3.19Å; L139-E143 VanDerWaalsContact O-CG 3.29Å; L139-E143 WeakPolarHBondContact O-CG 3.35Å; L139-E143 PolarHBondContact O-N 3.34Å; S140-E143 PolarHBondContact O-N 3.5Å; E143-S147 VanDerWaalsContact O-CB 3.27Å; E143-S147 WeakPolarHBondContact O-CB 3.15Å; E143-S147 PolarHBondContact O-N 3.37Å; E143-S147 PolarHBondContact O-OG 3Å
144T74.7Confident63.9Low78 Ų7873.4 Ų73.448%0.47941%0.413SS..Hα-helixtrans-72.3-43.2176.850.50000112.3S140 E141 T146 S147 N148S140-T144 WeakPolarHBondContact O-CB 3.44Å; S140-T144 WeakPolarHBondContact O-CG2 3.4Å; S140-T144 PolarHBondContact O-N 3.31Å; S140-T144 PolarHBondContact O-OG1 3.5Å; E141-T144 WeakPolarHBondContact CA-OG1 3.22Å; E141-T144 PolarHBondContact O-OG1 3.37Å; T144-T146 VanDerWaalsContact C-N 3.33Å; T144-T146 PolarHBondContact O-N 2.87Å; T144-S147 PolarHBondContact O-N 2.82Å; T144-N148 WeakPolarHBondContact O-CB 3.22Å; T144-N148 PolarHBondContact O-N 2.92Å; T144-N148 PolarHBondContact O-ND2 3.15Å
145A70Confident61.6Low59 Ų5974.9 Ų74.949%0.48843%0.434SS..Hα-helixtrans-60.6-40.7175.700000112.2E141 A149E141-A145 WeakPolarHBondContact O-CB 3.24Å; E141-A145 PolarHBondContact O-N 2.97Å; A145-A149 PolarHBondContact O-N 3.28Å; A145-A149 VanDerWaalsContact O-N 3.17Å
146T60.5Low59.4Low25 Ų2582.1 Ų82.115%0.15347%0.468CS..Hα-helixtrans-76.5-33.3179.4-47.20000112.2Q103 L104 T142 T144 A149 L150Q103-T146 HydrophobicContact CG-CG2 3.86Å; L104-T146 HydrophobicContact CD2-CG2 3.87Å; L104-T146 HydrophobicContact CG-CG2 4.31Å; T142-T146 WeakPolarHBondContact O-CB 3.35Å; T142-T146 PolarHBondContact O-N 3.42Å; T142-T146 PolarHBondContact O-OG1 2.78Å; T144-T146 VanDerWaalsContact C-N 3.33Å; T144-T146 PolarHBondContact O-N 2.87Å; T146-A149 PolarHBondContact O-N 3.45Å; T146-L150 PolarHBondContact O-N 2.92Å
147S55Low56.9Low65 Ų6585.5 Ų85.546%0.45549%0.489SS..Hα-helixtrans-71-36.5175.7-58.70000112.2E143 T144 A149 L150 S151E143-S147 VanDerWaalsContact O-CB 3.27Å; E143-S147 WeakPolarHBondContact O-CB 3.15Å; E143-S147 PolarHBondContact O-N 3.37Å; E143-S147 PolarHBondContact O-OG 3Å; T144-S147 PolarHBondContact O-N 2.82Å; S147-A149 VanDerWaalsContact C-N 3.29Å; S147-A149 PolarHBondContact O-N 3.38Å; S147-L150 PolarHBondContact O-N 2.74Å; S147-S151 PolarHBondContact O-N 2.8Å
148N45Very low54.6Low120 Ų12090 Ų9064%0.64251%0.51SS*.Hα-helixtrans-68.8-28.3173.2-67.9-16.9000112T144 L150T144-N148 WeakPolarHBondContact O-CB 3.22Å; T144-N148 PolarHBondContact O-N 2.92Å; T144-N148 PolarHBondContact O-ND2 3.15Å; N148-L150 VanDerWaalsContact C-N 3.32Å
149A44.8Very low52.3Low84 Ų8496.3 Ų96.369%0.69454%0.543SS*.Hα-helixtrans-71.7-22.1173.200000113.7A145 T146 S147A145-A149 PolarHBondContact O-N 3.28Å; A145-A149 VanDerWaalsContact O-N 3.17Å; T146-A149 PolarHBondContact O-N 3.45Å; S147-A149 VanDerWaalsContact C-N 3.29Å; S147-A149 PolarHBondContact O-N 3.38Å
150L43.6Very low50Low160 Ų160104.4 Ų104.484%0.83858%0.581SS**Hα-helixtrans-94.9-10179.2-144.480.4000113.4T146 S147 N148T146-L150 PolarHBondContact O-N 2.92Å; S147-L150 PolarHBondContact O-N 2.74Å; N148-L150 VanDerWaalsContact C-N 3.32Å
151S35.2Very low47.6Very low93 Ų93105 Ų10565%0.6560%0.595SS**SBendtrans-128.679.5-174.5167.90000111.3S147S147-S151 PolarHBondContact O-N 2.8Å
152G29.6Very low45.9Very low61 Ų61107 Ų10763%0.62962%0.617SS**SBendtrans76.7101.9155.100000118
153Y28.5Very low43.8Very low223 Ų223112.4 Ų112.488%0.87565%0.654SS**  trans39.2103.6148.6-61.8-83.6000120.4
154H30.5Very low42.3Very low159 Ų159116.7 Ų116.774%0.73668%0.678SS**  -172.9104.3120.2-138.5-81.9000108.6E156H154-E156 IonicContact CE1-OE2 3.7Å
155V32.9Very low41.4Very low141 Ų141116.1 Ų116.186%0.85569%0.687SS**  trans-108.679.5165-177.60000106.9
156E38.8Very low41.5Very low153 Ų153117.7 Ų117.772%0.71568%0.681SS**SBendtrans-116.4133.7144.7-74.6-171149.800105.8H154H154-E156 IonicContact CE1-OE2 3.7Å
157D33.6Very low42Very low130 Ų130124 Ų12470%0.69571%0.708SS**SBendtrans72.146.9168.8-71-7.7000119.7
158L32.9Very low43.3Very low164 Ų164124.5 Ų124.586%0.85970%0.702SS**  trans-122.2119144.2-75.9170.6000110.7E160L158-E160 PolarHBondContact O-N 2.94Å; L158-E160 VanDerWaalsContact O-N 3.13Å
159D35.9Very low44.8Very low149 Ų149121.1 Ų121.180%0.79768%0.68SS**  trans-49.7104.3-179.9-160.113.5000111G161D159-G161 PolarHBondContact O-N 3.21Å
160E34.9Very low46.1Very low171 Ų171121.6 Ų121.680%0.79968%0.677SS**  trans-74.567.5166-159.6-178.6-146.500107.9L158 S162L158-E160 PolarHBondContact O-N 2.94Å; L158-E160 VanDerWaalsContact O-N 3.13Å; E160-S162 PolarHBondContact O-N 2.96Å
161G34.4Very low47.7Very low58 Ų58115.5 Ų115.560%0.59865%0.647SS**  trans-75.3112.2170.300000110D159D159-G161 PolarHBondContact O-N 3.21Å
162S45.1Very low49.5Very low121 Ų121112.4 Ų112.485%0.84662%0.624SS**SBendtrans90.982.2160.7-154.70000118.2E160E160-S162 PolarHBondContact O-N 2.96Å
163C36.8Very low51.1Low118 Ų118119.8 Ų119.880%0.79763%0.633SS**SBendtrans-157.232.9135.1-155.40000114.1
164N46Very low52.5Low118 Ų118112.8 Ų112.863%0.63163%0.629SS**SBendtrans-141.5123.1169.8-79.8-48.3000108.4W166N164-W166 PolarHBondContact O-N 3.31Å
165G54.8Low54.1Low66 Ų66107 Ų10768%0.6860%0.603SS**  trans-59.471.7-17200000115.3H167G165-H167 PolarHBondContact O-CE1 3.34Å; G165-H167 PolarHBondContact O-ND1 3.35Å
166W72.6Confident55.6Low93 Ų93105.6 Ų105.635%0.35260%0.595SS.*  trans-92.6129.6170-55.7119.8000109.4N164 E210 K213 R214N164-W166 PolarHBondContact O-N 3.31Å; W166-E210 WeakPolarHBondContact CA-OE2 3.43Å; W166-E210 HydrophobicContact CD2-CG 4.43Å; W166-E210 HydrophobicContact CE3-CG 3.53Å; W166-E210 HydrophobicContact CZ3-CG 4.01Å; W166-K213 HydrophobicContact CH2-CD 3.99Å; W166-K213 HydrophobicContact CH2-CG 3.96Å; W166-K213 HydrophobicContact CZ3-CD 3.85Å; W166-K213 HydrophobicContact CZ3-CG 4.15Å; W166-R214 HydrophobicContact CD2-CG 4.11Å; W166-R214 HydrophobicContact CE3-CG 4.31Å; W166-R214 HydrophobicContact CH2-CG 4.4Å; W166-R214 HydrophobicContact CZ2-CG 4.22Å; W166-R214 HydrophobicContact CZ3-CG 4.44Å
167H71.6Confident57.1Low157 Ų157100.1 Ų100.173%0.72757%0.573SS**  trans-103.1-12.4-166.2-60.582.5000112.8G165 E210G165-H167 PolarHBondContact O-CE1 3.34Å; G165-H167 PolarHBondContact O-ND1 3.35Å; H167-E210 PolarHBondContact N-OE1 3.25Å; H167-E210 PolarHBondContact N-OE2 2.92Å
168F80.8Confident58.8Low76 Ų7695.6 Ų95.633%0.33355%0.552SS.*SBendtrans-112.9169-176.2-59.8-83000112.6E206 E207 E210 R214F168-E206 HydrophobicContact CE1-CB 4.34Å; F168-E206 HydrophobicContact CE2-CB 3.72Å; F168-E206 HydrophobicContact CZ-CB 3.46Å; F168-E206 VanDerWaalsContact CZ-CB 3.46Å; F168-E207 HydrophobicContact CB-CB 4.17Å; F168-E207 HydrophobicContact CB-CG 3.94Å; F168-E207 HydrophobicContact CD1-CB 3.7Å; F168-E207 HydrophobicContact CD1-CG 4.24Å; F168-E207 HydrophobicContact CE1-CB 4.22Å; F168-E207 HydrophobicContact CG-CB 3.87Å; F168-E207 HydrophobicContact CG-CG 4.21Å; F168-E210 WeakPolarHBondContact CB-OE1 3.33Å; F168-E210 HydrophobicContact CD2-CB 4.01Å; F168-E210 HydrophobicContact CD2-CG 4.43Å; F168-E210 PolarHBondContact N-OE1 3.41Å; F168-R214 PolarHBondContact O-NH2 3.17Å
169R77.4Confident60.8Low48 Ų4896.2 Ų96.218%0.18155%0.55CS.*PPolyproline II helixtrans-64.3156.4178.657.2173.9177.812614.1111.3A197 C199 S201 E207 W211R169-A197 PolarHBondContact NH1-O 2.76Å; R169-C199 PolarHBondContact NH1-O 3.12Å; R169-C199 PolarHBondContact NH2-O 3.3Å; R169-S201 PolarHBondContact NH2-O 3.07Å; R169-E207 WeakPolarHBondContact CD-OE1 3.39Å; R169-E207 WeakPolarHBondContact CG-OE1 3.39Å; R169-E207 IonicContact CZ-OE1 3.34Å; R169-E207 VanDerWaalsContact CZ-OE1 3.3Å; R169-E207 IonicContact NE-OE1 3.63Å; R169-E207 PolarHBondContact NE-OE1 3.4Å; R169-E207 IonicContact NH2-OE1 3.35Å; R169-E207 PolarHBondContact NH2-OE1 3.48Å; R169-W211 HydrophobicContact CG-CZ2 4.05Å; R169-W211 PolarHBondContact O-NE1 3.2Å
170P72.6Confident62.7Low95 Ų9593.5 Ų93.562%0.61753%0.533SS*.PPolyproline II helixtrans-64147.3178.825-34.3000112.2
171P77.6Confident65Low32 Ų3286.2 Ų86.221%0.20850%0.498CS..PPolyproline II helixtrans-64.9151.8175.725-32.2000111.9Y181 W211P171-Y181 HydrophobicContact CB-CE1 3.7Å; P171-W211 HydrophobicContact CB-CB 3.99Å; P171-W211 HydrophobicContact CB-CD2 3.85Å; P171-W211 HydrophobicContact CB-CE3 4.32Å; P171-W211 HydrophobicContact CB-CG 3.69Å; P171-W211 HydrophobicContact CG-CG 4.47Å
172P72.8Confident67.5Low28 Ų2887.1 Ų87.118%0.18249%0.492CS..PPolyproline II helixtrans-57.6141.4176-21.929.3000112.5I175 T200 W211P172-I175 HydrophobicContact CB-CD1 3.95Å; P172-I175 HydrophobicContact CG-CD1 4.16Å; P172-T200 HydrophobicContact CB-CG2 4.4Å; P172-T200 WeakPolarHBondContact CG-O 3.1Å; P172-W211 HydrophobicContact CG-CH2 4Å; P172-W211 HydrophobicContact CG-CZ3 3.93Å
173R62.1Low69.5Low215 Ų21583.8 Ų83.881%0.81147%0.465SS*.THydrogen-bonded Turntrans-74146176.6-62.3-174.7178.7-135.20.9110.2
174G58.3Low71.9Confident76 Ų7678.6 Ų78.678%0.78443%0.43SS*.THydrogen-bonded Turntrans92.21.1174.500000116
175I64.6Low73.7Confident39 Ų3980.6 Ų80.620%0.243%0.433CS..  trans-81.2123.3173.2-71.5170.3000109.4P172 S177 E180 Y181P172-I175 HydrophobicContact CB-CD1 3.95Å; P172-I175 HydrophobicContact CG-CD1 4.16Å; I175-S177 WeakPolarHBondContact CG2-O 3.25Å; I175-E180 HydrophobicContact CG2-CB 3.8Å; I175-Y181 HydrophobicContact CB-CE1 4.07Å; I175-Y181 HydrophobicContact CD1-CD1 3.54Å; I175-Y181 HydrophobicContact CD1-CE1 3.32Å; I175-Y181 HydrophobicContact CG1-CE1 4.27Å; I175-Y181 HydrophobicContact CG2-CD1 4.32Å; I175-Y181 HydrophobicContact CG2-CD2 4.47Å; I175-Y181 HydrophobicContact CG2-CE1 3.89Å; I175-Y181 HydrophobicContact CG2-CE2 4.06Å
176T64.8Low74.9Confident110 Ų11083.1 Ų83.168%0.67542%0.422SS*.  trans-98.5-10.3-173.646.50000113.9E180 Y215T176-E180 PolarHBondContact N-OE2 3.14Å; T176-E180 PolarHBondContact OG1-OE1 2.79Å; T176-Y215 PolarHBondContact O-OH 2.85Å
177S69Low75.5Confident38 Ų3881.9 Ų81.927%0.26642%0.419SS..  trans-134.3147179.4175.70000112.6I175 E179 E180I175-S177 WeakPolarHBondContact CG2-O 3.25Å; S177-E179 PolarHBondContact O-N 2.86Å; S177-E179 PolarHBondContact OG-N 3.45Å; S177-E180 WeakPolarHBondContact CB-OE1 3.28Å; S177-E180 PolarHBondContact O-N 2.69Å
178S69.1Low76Confident36 Ų3679 Ų7925%0.25241%0.408SS..THydrogen-bonded Turntrans-64.6-21.8174-174.40000113.5Q212S178-Q212 PolarHBondContact O-NE2 3.5Å; S178-Q212 WeakPolarHBondContact OG-CG 3.3Å
179E74.7Confident76Confident176 Ų17682.4 Ų82.482%0.82243%0.425SS*.THydrogen-bonded Turntrans-83.9-14.8-177.2-63.2179.317900112.8S177 Y181S177-E179 PolarHBondContact O-N 2.86Å; S177-E179 PolarHBondContact OG-N 3.45Å; E179-Y181 VanDerWaalsContact C-N 3.31Å
180E77.4Confident76.1Confident93 Ų9386.4 Ų86.444%0.43545%0.446SS..SBendtrans-78.5-15178.6-72.3167.2-146.800112.6I175 T176 S177 T182I175-E180 HydrophobicContact CG2-CB 3.8Å; T176-E180 PolarHBondContact N-OE2 3.14Å; T176-E180 PolarHBondContact OG1-OE1 2.79Å; S177-E180 WeakPolarHBondContact CB-OE1 3.28Å; S177-E180 PolarHBondContact O-N 2.69Å; E180-T182 PolarHBondContact O-N 3.06Å
181Y81.9Confident76.3Confident18 Ų1884.1 Ų84.17%0.07144%0.44CS..  trans-73.1125.1174.8-64.1-63.5000111P171 I175 E179 L208 W211 Q212 Y215P171-Y181 HydrophobicContact CB-CE1 3.7Å; I175-Y181 HydrophobicContact CB-CE1 4.07Å; I175-Y181 HydrophobicContact CD1-CD1 3.54Å; I175-Y181 HydrophobicContact CD1-CE1 3.32Å; I175-Y181 HydrophobicContact CG1-CE1 4.27Å; I175-Y181 HydrophobicContact CG2-CD1 4.32Å; I175-Y181 HydrophobicContact CG2-CD2 4.47Å; I175-Y181 HydrophobicContact CG2-CE1 3.89Å; I175-Y181 HydrophobicContact CG2-CE2 4.06Å; E179-Y181 VanDerWaalsContact C-N 3.31Å; Y181-L208 HydrophobicContact CG-CD1 4.46Å; Y181-W211 AromaticContact CD1-CE3 3.62Å; Y181-W211 HydrophobicContact CD1-CE3 3.62Å; Y181-W211 HydrophobicContact CD1-CZ3 4.26Å; Y181-W211 HydrophobicContact CE1-CE3 4.07Å; Y181-W211 HydrophobicContact CG-CE3 4.33Å; Y181-Q212 HydrophobicContact CD2-CG 4.13Å; Y181-Y215 HydrophobicContact CE2-CD2 4.45Å; Y181-Y215 HydrophobicContact CE2-CG 4.42Å
182T86.9Confident76.3Confident76 Ų7688.7 Ų88.747%0.46646%0.461SS..  trans-130.8158.1-175.453.60000112E180 S201 A202E180-T182 PolarHBondContact O-N 3.06Å; T182-S201 CarbonylContact O-C 3.53Å; T182-S201 VanDerWaalsContact O-CA 3.24Å; T182-S201 WeakPolarHBondContact O-CA 3.38Å; T182-S201 VanDerWaalsContact O-CB 3.27Å; T182-S201 WeakPolarHBondContact O-CB 3.31Å; T182-S201 PolarHBondContact OG1-OG 3.35Å; T182-A202 PolarHBondContact O-N 2.91Å
183L88Confident76.7Confident51 Ų5188.1 Ų88.127%0.26746%0.458SS..BIsolated β-bridgetrans-79.4142.1175.9-64.5172.1000112.5K185 L188 A202 S204 L208L183-K185 PolarHBondContact O-N 2.97Å; L183-L188 HydrophobicContact CB-CD1 3.83Å; L183-L188 HydrophobicContact CD1-CD1 3.94Å; L183-L188 HydrophobicContact CG-CD1 4.4Å; L183-A202 CarbonylContact C-O 3.51Å; L183-A202 WeakPolarHBondContact CA-O 3.36Å; L183-A202 HydrophobicContact CD2-CB 4.21Å; L183-S204 VanDerWaalsContact CD2-O 3.3Å; L183-S204 WeakPolarHBondContact CD2-O 3.35Å; L183-L208 HydrophobicContact CD2-CB 3.94Å; L183-L208 HydrophobicContact CD2-CD2 3.83Å; L183-L208 HydrophobicContact CG-CD2 3.88Å
184C85.9Confident77.2Confident10 Ų1088.5 Ų88.57%0.06846%0.459CS..  trans-77.699175.5-177.30000110R186 F187 L188 A202C184-R186 VanDerWaalsContact C-N 3.28Å; C184-R186 PolarHBondContact O-N 2.94Å; C184-F187 HydrophobicContact CB-CB 4.03Å; C184-F187 PolarHBondContact O-N 2.93Å; C184-F187 VanDerWaalsContact O-N 3.14Å; C184-L188 WeakPolarHBondContact O-CG 3.31Å; C184-L188 PolarHBondContact O-N 3.49Å; C184-L188 VanDerWaalsContact O-N 3.1Å; C184-A202 WeakPolarHBondContact CB-O 3.45Å; C184-A202 PolarHBondContact N-O 2.87Å
185K84.9Confident77.5Confident160 Ų16091.6 Ų91.670%0.69645%0.448SS*.Hα-helixtrans-53.4-42.5179.7-63.2-175178-177.60113.2L183 F187 L188 E189L183-K185 PolarHBondContact O-N 2.97Å; K185-F187 PolarHBondContact O-N 3.47Å; K185-L188 PolarHBondContact O-N 3.24Å; K185-E189 WeakPolarHBondContact O-CB 3.43Å; K185-E189 VanDerWaalsContact O-CG 3.28Å; K185-E189 WeakPolarHBondContact O-CG 3.39Å; K185-E189 PolarHBondContact O-N 3.24Å
186R80.3Confident78.1Confident119 Ų11991.3 Ų91.345%0.44946%0.455SS..Hα-helixtrans-64.3-38.7179.9-102.7-176.1-96.2167.6-6.1113.2C184 Q190C184-R186 VanDerWaalsContact C-N 3.28Å; C184-R186 PolarHBondContact O-N 2.94Å; R186-Q190 WeakPolarHBondContact O-CB 3.31Å; R186-Q190 PolarHBondContact O-N 2.97Å
187F85.1Confident78.4Confident67 Ų6790.2 Ų90.229%0.29446%0.457SS..Hα-helixtrans-70.5-40.5177.1-167.4-86.4000111.1C184 K185 E189 G191 C193 H203C184-F187 HydrophobicContact CB-CB 4.03Å; C184-F187 PolarHBondContact O-N 2.93Å; C184-F187 VanDerWaalsContact O-N 3.14Å; K185-F187 PolarHBondContact O-N 3.47Å; F187-E189 VanDerWaalsContact C-N 3.35Å; F187-E189 PolarHBondContact O-N 3.34Å; F187-G191 WeakPolarHBondContact CE2-O 3.2Å; F187-G191 WeakPolarHBondContact O-CA 3.11Å; F187-G191 PolarHBondContact O-N 3.36Å; F187-C193 HydrophobicContact CB-CB 4.14Å; F187-C193 HydrophobicContact CD2-CB 3.72Å; F187-C193 HydrophobicContact CG-CB 4.41Å; F187-H203 HydrophobicContact CB-CB 4.26Å; F187-H203 HydrophobicContact CD1-CB 3.49Å; F187-H203 VanDerWaalsContact CD1-CB 3.49Å; F187-H203 AromaticContact CD1-CG 3.96Å; F187-H203 WeakPolarHBondContact CD1-O 3.46Å; F187-H203 HydrophobicContact CD2-CB 4.06Å; F187-H203 AromaticContact CD2-CE1 3.86Å; F187-H203 AromaticContact CD2-CG 3.63Å; F187-H203 AromaticContact CD2-ND1 3.51Å; F187-H203 HydrophobicContact CE1-CB 3.71Å; F187-H203 HydrophobicContact CE2-CB 4.27Å; F187-H203 AromaticContact CE2-ND1 3.66Å; F187-H203 HydrophobicContact CG-CB 3.66Å; F187-H203 AromaticContact CG-CD2 3.88Å; F187-H203 AromaticContact CG-CG 3.56Å; F187-H203 AromaticContact CG-ND1 3.96Å; F187-H203 HydrophobicContact CZ-CB 4.1Å
188L82.8Confident78.4Confident95 Ų9596.6 Ų96.650%0.49748%0.483SS..Hα-helixtrans-64.2-38.7177.2-67.4177.5000112.6L183 C184 K185L183-L188 HydrophobicContact CB-CD1 3.83Å; L183-L188 HydrophobicContact CD1-CD1 3.94Å; L183-L188 HydrophobicContact CG-CD1 4.4Å; C184-L188 WeakPolarHBondContact O-CG 3.31Å; C184-L188 PolarHBondContact O-N 3.49Å; C184-L188 VanDerWaalsContact O-N 3.1Å; K185-L188 PolarHBondContact O-N 3.24Å
189E80.6Confident78.8Confident148 Ų14895.3 Ų95.369%0.69247%0.473SS*.Hα-helixtrans-81.4-33.7-177.4-71.1167.5-172.300113.4K185 F187K185-E189 WeakPolarHBondContact O-CB 3.43Å; K185-E189 VanDerWaalsContact O-CG 3.28Å; K185-E189 WeakPolarHBondContact O-CG 3.39Å; K185-E189 PolarHBondContact O-N 3.24Å; F187-E189 VanDerWaalsContact C-N 3.35Å; F187-E189 PolarHBondContact O-N 3.34Å
190Q79.4Confident79Confident132 Ų13291.7 Ų91.762%0.61746%0.464SS*.Hα-helixtrans-120.4-5.2-169.4-57.1-178.3-1300113.9R186 I192R186-Q190 WeakPolarHBondContact O-CB 3.31Å; R186-Q190 PolarHBondContact O-N 2.97Å; Q190-I192 PolarHBondContact O-N 3.5Å; Q190-I192 VanDerWaalsContact O-N 3.08Å
191G77Confident79.3Confident48 Ų4888.5 Ų88.550%0.49545%0.451SS..SBendtrans67.10.7-174.700000114.7F187F187-G191 WeakPolarHBondContact CE2-O 3.2Å; F187-G191 WeakPolarHBondContact O-CA 3.11Å; F187-G191 PolarHBondContact O-N 3.36Å
192I76.2Confident79.6Confident127 Ų12787.6 Ų87.665%0.65145%0.448SS*.  trans-137.9126.6-173.3-57176.8000109.6Q190Q190-I192 PolarHBondContact O-N 3.5Å; Q190-I192 VanDerWaalsContact O-N 3.08Å
193C81.1Confident79.5Confident16 Ų1685.1 Ų85.111%0.10843%0.431CS..  trans-113.5125.7174.1179.90000110.1F187 Y195 G196 C199 H203F187-C193 HydrophobicContact CB-CB 4.14Å; F187-C193 HydrophobicContact CD2-CB 3.72Å; F187-C193 HydrophobicContact CG-CB 4.41Å; C193-Y195 PolarHBondContact O-N 2.97Å; C193-Y195 VanDerWaalsContact O-N 3.15Å; C193-Y195 PolarHBondContact SG-N 3.03Å; C193-Y195 VanDerWaalsContact SG-N 3.43Å; C193-G196 PolarHBondContact O-N 3.37Å; C193-G196 VanDerWaalsContact O-N 3.11Å; C193-C199 VanDerWaalsContact SG-SG 3.68Å; C193-H203 WeakPolarHBondContact CB-NE2 3.42Å; C193-H203 PolarHBondContact SG-NE2 3.2Å
194R73.1Confident79.4Confident224 Ų22483.9 Ų83.985%0.84543%0.427SS*.THydrogen-bonded Turntrans-61.4-22.7177.6-64.9-174.9-177.2177.5-0.5113.6
195Y65.9Low79.4Confident141 Ų14188.5 Ų88.555%0.55345%0.447SS*.THydrogen-bonded Turntrans-92.4-8.1-179.5-55.2-73.5000113.2C193 A197 Q198 C199C193-Y195 PolarHBondContact O-N 2.97Å; C193-Y195 VanDerWaalsContact O-N 3.15Å; C193-Y195 PolarHBondContact SG-N 3.03Å; C193-Y195 VanDerWaalsContact SG-N 3.43Å; Y195-A197 PolarHBondContact O-N 3.26Å; Y195-Q198 WeakPolarHBondContact O-CA 3.43Å; Y195-Q198 WeakPolarHBondContact O-CB 3.36Å; Y195-Q198 PolarHBondContact O-N 3.3Å; Y195-C199 PolarHBondContact O-N 2.93Å
196G76.5Confident79.5Confident32 Ų3286.3 Ų86.333%0.3344%0.439SS..G310 helixtrans46.1-128.5174.600000113.6C193 Q198 C199 H203C193-G196 PolarHBondContact O-N 3.37Å; C193-G196 VanDerWaalsContact O-N 3.11Å; G196-Q198 PolarHBondContact O-N 3.27Å; G196-C199 WeakPolarHBondContact O-CB 3.42Å; G196-C199 PolarHBondContact O-N 3.27Å; G196-H203 PolarHBondContact O-CE1 2.88Å; G196-H203 VanDerWaalsContact O-CE1 3.27Å
197A70.1Confident79.7Confident87 Ų8781.1 Ų81.172%0.71942%0.42SS*.G310 helixtrans-62.7-19.9179.500000114.3R169 Y195R169-A197 PolarHBondContact NH1-O 2.76Å; Y195-A197 PolarHBondContact O-N 3.26Å
198Q68.9Low79.7Confident173 Ų17378.6 Ų78.681%0.80841%0.41SS*.G310 helixtrans-91.11.9-179.8-60179.6-6.900113.2Y195 G196 T200Y195-Q198 WeakPolarHBondContact O-CA 3.43Å; Y195-Q198 WeakPolarHBondContact O-CB 3.36Å; Y195-Q198 PolarHBondContact O-N 3.3Å; G196-Q198 PolarHBondContact O-N 3.27Å; Q198-T200 PolarHBondContact O-N 3.36Å
199C77.3Confident79.8Confident9 Ų976.3 Ų76.36%0.06141%0.405CS..  trans-65129.8179.1-1700000111.3R169 C193 Y195 G196 S201 H203R169-C199 PolarHBondContact NH1-O 3.12Å; R169-C199 PolarHBondContact NH2-O 3.3Å; C193-C199 VanDerWaalsContact SG-SG 3.68Å; Y195-C199 PolarHBondContact O-N 2.93Å; G196-C199 WeakPolarHBondContact O-CB 3.42Å; G196-C199 PolarHBondContact O-N 3.27Å; C199-S201 PolarHBondContact O-N 3.31Å; C199-S201 PolarHBondContact SG-O 3.38Å; C199-H203 VanDerWaalsContact CB-NE2 3.27Å; C199-H203 WeakPolarHBondContact CB-NE2 3.31Å
200T79.4Confident80Confident100 Ų10070.1 Ų70.161%0.61338%0.376SS*.SBendtrans-77.3-6179.150.50000113.9P172 Q198P172-T200 HydrophobicContact CB-CG2 4.4Å; P172-T200 WeakPolarHBondContact CG-O 3.1Å; Q198-T200 PolarHBondContact O-N 3.36Å
201S85.1Confident80.3Confident25 Ų2563.9 Ų63.918%0.17535%0.346CS..SBendtrans-111147.1176-59.40000110.8R169 T182 C199R169-S201 PolarHBondContact NH2-O 3.07Å; T182-S201 CarbonylContact O-C 3.53Å; T182-S201 VanDerWaalsContact O-CA 3.24Å; T182-S201 WeakPolarHBondContact O-CA 3.38Å; T182-S201 VanDerWaalsContact O-CB 3.27Å; T182-S201 WeakPolarHBondContact O-CB 3.31Å; T182-S201 PolarHBondContact OG1-OG 3.35Å; C199-S201 PolarHBondContact O-N 3.31Å; C199-S201 PolarHBondContact SG-O 3.38Å
202A86.4Confident80.6Confident0 Ų064.7 Ų64.70%034%0.337CS..BIsolated β-bridgetrans-71.7137.6-179.800000111.5T182 L183 C184 E207 L208 W211T182-A202 PolarHBondContact O-N 2.91Å; L183-A202 CarbonylContact C-O 3.51Å; L183-A202 WeakPolarHBondContact CA-O 3.36Å; L183-A202 HydrophobicContact CD2-CB 4.21Å; C184-A202 WeakPolarHBondContact CB-O 3.45Å; C184-A202 PolarHBondContact N-O 2.87Å; A202-E207 HydrophobicContact CB-CB 4.29Å; A202-E207 HydrophobicContact CB-CG 3.99Å; A202-L208 HydrophobicContact CB-CB 3.72Å; A202-L208 HydrophobicContact CB-CD1 4.29Å; A202-W211 HydrophobicContact CB-CE3 4.15Å; A202-W211 HydrophobicContact CB-CH2 4.37Å; A202-W211 HydrophobicContact CB-CZ3 4.01Å
203H85.9Confident80.9Confident23 Ų2364.8 Ų64.811%0.10633%0.333CS..SBendtrans-85.6-12.7-178.4-70.3176.7000113.2F187 C193 G196 C199 E207F187-H203 HydrophobicContact CB-CB 4.26Å; F187-H203 HydrophobicContact CD1-CB 3.49Å; F187-H203 VanDerWaalsContact CD1-CB 3.49Å; F187-H203 AromaticContact CD1-CG 3.96Å; F187-H203 WeakPolarHBondContact CD1-O 3.46Å; F187-H203 HydrophobicContact CD2-CB 4.06Å; F187-H203 AromaticContact CD2-CE1 3.86Å; F187-H203 AromaticContact CD2-CG 3.63Å; F187-H203 AromaticContact CD2-ND1 3.51Å; F187-H203 HydrophobicContact CE1-CB 3.71Å; F187-H203 HydrophobicContact CE2-CB 4.27Å; F187-H203 AromaticContact CE2-ND1 3.66Å; F187-H203 HydrophobicContact CG-CB 3.66Å; F187-H203 AromaticContact CG-CD2 3.88Å; F187-H203 AromaticContact CG-CG 3.56Å; F187-H203 AromaticContact CG-ND1 3.96Å; F187-H203 HydrophobicContact CZ-CB 4.1Å; C193-H203 WeakPolarHBondContact CB-NE2 3.42Å; C193-H203 PolarHBondContact SG-NE2 3.2Å; G196-H203 PolarHBondContact O-CE1 2.88Å; G196-H203 VanDerWaalsContact O-CE1 3.27Å; C199-H203 VanDerWaalsContact CB-NE2 3.27Å; C199-H203 WeakPolarHBondContact CB-NE2 3.31Å; H203-E207 WeakPolarHBondContact CA-OE2 3.34Å; H203-E207 VanDerWaalsContact CB-OE2 3.27Å; H203-E207 WeakPolarHBondContact CB-OE2 3.39Å; H203-E207 PolarHBondContact N-OE2 3.36Å
204S85.2Confident80.8Confident26 Ų2666.6 Ų66.618%0.18234%0.338CS..SBendtrans-144.6167.2170.889.70000112.3L183 E206 E207 L208L183-S204 VanDerWaalsContact CD2-O 3.3Å; L183-S204 WeakPolarHBondContact CD2-O 3.35Å; S204-E206 VanDerWaalsContact C-N 3.29Å; S204-E206 WeakPolarHBondContact CB-OE2 3.47Å; S204-E206 PolarHBondContact OG-N 2.94Å; S204-E206 PolarHBondContact OG-OE2 3.43Å; S204-E207 PolarHBondContact N-OE2 2.9Å; S204-E207 PolarHBondContact O-N 2.87Å; S204-E207 PolarHBondContact OG-N 3.48Å; S204-E207 VanDerWaalsContact OG-N 3.14Å; S204-L208 PolarHBondContact O-N 2.99Å; S204-L208 VanDerWaalsContact O-N 3.12Å
205Q87Confident81.1Confident107 Ų10758.2 Ų58.250%0.531%0.306SS..Hα-helixtrans-67.5-34.3177.2-1726142.400111.5L208 A209Q205-L208 PolarHBondContact O-N 3.3Å; Q205-A209 WeakPolarHBondContact O-CB 3.28Å; Q205-A209 PolarHBondContact O-N 3.38Å
206E86.3Confident81.7Confident114 Ų11453.6 Ų53.653%0.53330%0.298SS..Hα-helixtrans-68.4-40.6177.8-55.872.3-153.800110.9F168 S204 A209 E210F168-E206 HydrophobicContact CE1-CB 4.34Å; F168-E206 HydrophobicContact CE2-CB 3.72Å; F168-E206 HydrophobicContact CZ-CB 3.46Å; F168-E206 VanDerWaalsContact CZ-CB 3.46Å; S204-E206 VanDerWaalsContact C-N 3.29Å; S204-E206 WeakPolarHBondContact CB-OE2 3.47Å; S204-E206 PolarHBondContact OG-N 2.94Å; S204-E206 PolarHBondContact OG-OE2 3.43Å; E206-A209 PolarHBondContact O-N 3.49Å; E206-E210 WeakPolarHBondContact O-CB 3.36Å; E206-E210 PolarHBondContact O-N 3.23Å
207E84Confident81.7Confident9 Ų954.2 Ų54.24%0.04230%0.297CS..Hα-helixtrans-63.5-44.6174.6177.8176.1-16500111.8F168 R169 A202 H203 S204 A209 E210 W211F168-E207 HydrophobicContact CB-CB 4.17Å; F168-E207 HydrophobicContact CB-CG 3.94Å; F168-E207 HydrophobicContact CD1-CB 3.7Å; F168-E207 HydrophobicContact CD1-CG 4.24Å; F168-E207 HydrophobicContact CE1-CB 4.22Å; F168-E207 HydrophobicContact CG-CB 3.87Å; F168-E207 HydrophobicContact CG-CG 4.21Å; R169-E207 WeakPolarHBondContact CD-OE1 3.39Å; R169-E207 WeakPolarHBondContact CG-OE1 3.39Å; R169-E207 IonicContact CZ-OE1 3.34Å; R169-E207 VanDerWaalsContact CZ-OE1 3.3Å; R169-E207 IonicContact NE-OE1 3.63Å; R169-E207 PolarHBondContact NE-OE1 3.4Å; R169-E207 IonicContact NH2-OE1 3.35Å; R169-E207 PolarHBondContact NH2-OE1 3.48Å; A202-E207 HydrophobicContact CB-CB 4.29Å; A202-E207 HydrophobicContact CB-CG 3.99Å; H203-E207 WeakPolarHBondContact CA-OE2 3.34Å; H203-E207 VanDerWaalsContact CB-OE2 3.27Å; H203-E207 WeakPolarHBondContact CB-OE2 3.39Å; H203-E207 PolarHBondContact N-OE2 3.36Å; S204-E207 PolarHBondContact N-OE2 2.9Å; S204-E207 PolarHBondContact O-N 2.87Å; S204-E207 PolarHBondContact OG-N 3.48Å; S204-E207 VanDerWaalsContact OG-N 3.14Å; E207-A209 PolarHBondContact O-N 3.37Å; E207-E210 PolarHBondContact O-N 3.28Å; E207-W211 HydrophobicContact CG-CD2 4.42Å; E207-W211 HydrophobicContact CG-CZ2 4.09Å; E207-W211 PolarHBondContact O-N 3.24Å; E207-W211 WeakPolarHBondContact OE1-CZ2 3.01Å
208L86.1Confident81.8Confident14 Ų1458.5 Ų58.57%0.07330%0.295CS..Hα-helixtrans-60.8-46.2176.8179.458.3000111.6Y181 L183 A202 S204 Q205 E210 W211 Q212Y181-L208 HydrophobicContact CG-CD1 4.46Å; L183-L208 HydrophobicContact CD2-CB 3.94Å; L183-L208 HydrophobicContact CD2-CD2 3.83Å; L183-L208 HydrophobicContact CG-CD2 3.88Å; A202-L208 HydrophobicContact CB-CB 3.72Å; A202-L208 HydrophobicContact CB-CD1 4.29Å; S204-L208 PolarHBondContact O-N 2.99Å; S204-L208 VanDerWaalsContact O-N 3.12Å; Q205-L208 PolarHBondContact O-N 3.3Å; L208-E210 VanDerWaalsContact C-N 3.29Å; L208-E210 PolarHBondContact O-N 2.67Å; L208-W211 PolarHBondContact O-N 3.44Å; L208-Q212 HydrophobicContact CD1-CG 4.49Å; L208-Q212 WeakPolarHBondContact O-CG 3.27Å; L208-Q212 PolarHBondContact O-N 2.96Å
209A84.9Confident82Confident48 Ų4854.3 Ų54.340%0.39728%0.277SS..Hα-helixtrans-62.5-37.8177.800000111.7Q205 E206 E207 K213Q205-A209 WeakPolarHBondContact O-CB 3.28Å; Q205-A209 PolarHBondContact O-N 3.38Å; E206-A209 PolarHBondContact O-N 3.49Å; E207-A209 PolarHBondContact O-N 3.37Å; A209-K213 VanDerWaalsContact O-CB 3.3Å; A209-K213 WeakPolarHBondContact O-CB 3.48Å; A209-K213 PolarHBondContact O-N 2.83Å
210E85.3Confident81.9Confident18 Ų1858.6 Ų58.68%0.08430%0.298CS..Hα-helixtrans-66.7-41.9175.9-166.7175.496.100111.8W166 H167 F168 E206 E207 L208 Q212 K213 R214W166-E210 WeakPolarHBondContact CA-OE2 3.43Å; W166-E210 HydrophobicContact CD2-CG 4.43Å; W166-E210 HydrophobicContact CE3-CG 3.53Å; W166-E210 HydrophobicContact CZ3-CG 4.01Å; H167-E210 PolarHBondContact N-OE1 3.25Å; H167-E210 PolarHBondContact N-OE2 2.92Å; F168-E210 WeakPolarHBondContact CB-OE1 3.33Å; F168-E210 HydrophobicContact CD2-CB 4.01Å; F168-E210 HydrophobicContact CD2-CG 4.43Å; F168-E210 PolarHBondContact N-OE1 3.41Å; E206-E210 WeakPolarHBondContact O-CB 3.36Å; E206-E210 PolarHBondContact O-N 3.23Å; E207-E210 PolarHBondContact O-N 3.28Å; L208-E210 VanDerWaalsContact C-N 3.29Å; L208-E210 PolarHBondContact O-N 2.67Å; E210-Q212 PolarHBondContact O-N 2.78Å; E210-K213 PolarHBondContact O-N 3.49Å; E210-R214 WeakPolarHBondContact O-CB 3.19Å; E210-R214 WeakPolarHBondContact O-CG 3.42Å; E210-R214 PolarHBondContact O-N 2.85Å; E210-R214 IonicContact OE1-CZ 3.85Å; E210-R214 IonicContact OE1-NE 3.27Å; E210-R214 PolarHBondContact OE1-NE 3.5Å; E210-R214 IonicContact OE1-NH2 2.71Å; E210-R214 PolarHBondContact OE1-NH2 3.33Å
211W85.2Confident81.3Confident0 Ų059 Ų590%029%0.292CS..Hα-helixtrans-60.1-45.6175.6-71.85000112.2R169 P171 P172 Y181 A202 E207 L208 K213 R214 Y215R169-W211 HydrophobicContact CG-CZ2 4.05Å; R169-W211 PolarHBondContact O-NE1 3.2Å; P171-W211 HydrophobicContact CB-CB 3.99Å; P171-W211 HydrophobicContact CB-CD2 3.85Å; P171-W211 HydrophobicContact CB-CE3 4.32Å; P171-W211 HydrophobicContact CB-CG 3.69Å; P171-W211 HydrophobicContact CG-CG 4.47Å; P172-W211 HydrophobicContact CG-CH2 4Å; P172-W211 HydrophobicContact CG-CZ3 3.93Å; Y181-W211 AromaticContact CD1-CE3 3.62Å; Y181-W211 HydrophobicContact CD1-CE3 3.62Å; Y181-W211 HydrophobicContact CD1-CZ3 4.26Å; Y181-W211 HydrophobicContact CE1-CE3 4.07Å; Y181-W211 HydrophobicContact CG-CE3 4.33Å; A202-W211 HydrophobicContact CB-CE3 4.15Å; A202-W211 HydrophobicContact CB-CH2 4.37Å; A202-W211 HydrophobicContact CB-CZ3 4.01Å; E207-W211 HydrophobicContact CG-CD2 4.42Å; E207-W211 HydrophobicContact CG-CZ2 4.09Å; E207-W211 PolarHBondContact O-N 3.24Å; E207-W211 WeakPolarHBondContact OE1-CZ2 3.01Å; L208-W211 PolarHBondContact O-N 3.44Å; W211-K213 PolarHBondContact O-N 3.3Å; W211-R214 PolarHBondContact O-N 3.27Å; W211-Y215 PolarHBondContact O-N 2.95Å
212Q83.1Confident80.3Confident65 Ų6562.8 Ų62.830%0.30431%0.309SS..Hα-helixtrans-63.1-41.6176-68.6178.5-29.800111.6S178 Y181 L208 E210 Y215 A216S178-Q212 PolarHBondContact O-NE2 3.5Å; S178-Q212 WeakPolarHBondContact OG-CG 3.3Å; Y181-Q212 HydrophobicContact CD2-CG 4.13Å; L208-Q212 HydrophobicContact CD1-CG 4.49Å; L208-Q212 WeakPolarHBondContact O-CG 3.27Å; L208-Q212 PolarHBondContact O-N 2.96Å; E210-Q212 PolarHBondContact O-N 2.78Å; Q212-Y215 PolarHBondContact O-N 3.27Å; Q212-A216 PolarHBondContact O-N 2.83Å
213K81.8Confident79.4Confident129 Ų12969.3 Ų69.356%0.56134%0.338SS*.Hα-helixtrans-65.1-38.8176.4-173.4175.4172.3-172.30112.4W166 A209 E210 W211 S217W166-K213 HydrophobicContact CH2-CD 3.99Å; W166-K213 HydrophobicContact CH2-CG 3.96Å; W166-K213 HydrophobicContact CZ3-CD 3.85Å; W166-K213 HydrophobicContact CZ3-CG 4.15Å; A209-K213 VanDerWaalsContact O-CB 3.3Å; A209-K213 WeakPolarHBondContact O-CB 3.48Å; A209-K213 PolarHBondContact O-N 2.83Å; E210-K213 PolarHBondContact O-N 3.49Å; W211-K213 PolarHBondContact O-N 3.3Å; K213-S217 WeakPolarHBondContact O-CB 3.25Å; K213-S217 PolarHBondContact O-N 2.92Å; K213-S217 PolarHBondContact O-OG 2.56Å
214R80.5Confident78.4Confident55 Ų5573.1 Ų73.121%0.20836%0.356CS..Hα-helixtrans-64.1-42.1173.3-72.9-175.7-165.7-160.917.6111.3W166 F168 E210 W211 S217 R218W166-R214 HydrophobicContact CD2-CG 4.11Å; W166-R214 HydrophobicContact CE3-CG 4.31Å; W166-R214 HydrophobicContact CH2-CG 4.4Å; W166-R214 HydrophobicContact CZ2-CG 4.22Å; W166-R214 HydrophobicContact CZ3-CG 4.44Å; F168-R214 PolarHBondContact O-NH2 3.17Å; E210-R214 WeakPolarHBondContact O-CB 3.19Å; E210-R214 WeakPolarHBondContact O-CG 3.42Å; E210-R214 PolarHBondContact O-N 2.85Å; E210-R214 IonicContact OE1-CZ 3.85Å; E210-R214 IonicContact OE1-NE 3.27Å; E210-R214 PolarHBondContact OE1-NE 3.5Å; E210-R214 IonicContact OE1-NH2 2.71Å; E210-R214 PolarHBondContact OE1-NH2 3.33Å; W211-R214 PolarHBondContact O-N 3.27Å; R214-S217 PolarHBondContact O-N 2.91Å; R214-R218 PolarHBondContact O-N 3.05Å
215Y77.9Confident76.7Confident47 Ų4777.8 Ų77.818%0.18437%0.374CS..Hα-helixtrans-62.5-47.5176.1179.5-89.9000112T176 Y181 W211 Q212 S217 R218 L219T176-Y215 PolarHBondContact O-OH 2.85Å; Y181-Y215 HydrophobicContact CE2-CD2 4.45Å; Y181-Y215 HydrophobicContact CE2-CG 4.42Å; W211-Y215 PolarHBondContact O-N 2.95Å; Q212-Y215 PolarHBondContact O-N 3.27Å; Y215-S217 VanDerWaalsContact C-N 3.33Å; Y215-S217 PolarHBondContact O-N 3Å; Y215-R218 WeakPolarHBondContact O-CB 3.28Å; Y215-R218 PolarHBondContact O-N 3.13Å; Y215-R218 VanDerWaalsContact O-N 3.14Å; Y215-L219 HydrophobicContact CD1-CD1 3.95Å; Y215-L219 HydrophobicContact CD1-CG 4.4Å; Y215-L219 HydrophobicContact CE1-CD1 3.28Å; Y215-L219 HydrophobicContact CE1-CG 3.94Å; Y215-L219 PolarHBondContact O-N 2.52Å
216A79.3Confident75.2Confident45 Ų4578.2 Ų78.237%0.37238%0.38SS..Hα-helixtrans-60.1-42.1175.400000112.2Q212 R218 L219 I220Q212-A216 PolarHBondContact O-N 2.83Å; A216-R218 VanDerWaalsContact C-N 3.31Å; A216-R218 PolarHBondContact O-N 2.77Å; A216-L219 PolarHBondContact O-N 3.05Å; A216-I220 VanDerWaalsContact O-CG1 3.31Å; A216-I220 WeakPolarHBondContact O-CG1 3.27Å; A216-I220 PolarHBondContact O-N 3.21Å
217S75.7Confident73.7Confident45 Ų4577 Ų7732%0.31538%0.375SS..Hα-helixtrans-62.5-38.2176-57.20000112K213 R214 Y215 K221K213-S217 WeakPolarHBondContact O-CB 3.25Å; K213-S217 PolarHBondContact O-N 2.92Å; K213-S217 PolarHBondContact O-OG 2.56Å; R214-S217 PolarHBondContact O-N 2.91Å; Y215-S217 VanDerWaalsContact C-N 3.33Å; Y215-S217 PolarHBondContact O-N 3Å; S217-K221 WeakPolarHBondContact O-CG 3.3Å; S217-K221 PolarHBondContact O-N 2.74Å
218R72.2Confident71.8Confident177 Ų17781.9 Ų81.967%0.66840%0.401SS*.Hα-helixtrans-63.5-46174.7-172.9-179.4-171.1158.24.6111.5R214 Y215 A216 K221 L222R214-R218 PolarHBondContact O-N 3.05Å; Y215-R218 WeakPolarHBondContact O-CB 3.28Å; Y215-R218 PolarHBondContact O-N 3.13Å; Y215-R218 VanDerWaalsContact O-N 3.14Å; A216-R218 VanDerWaalsContact C-N 3.31Å; A216-R218 PolarHBondContact O-N 2.77Å; R218-K221 PolarHBondContact O-N 3.45Å; R218-L222 WeakPolarHBondContact O-CB 3.25Å; R218-L222 PolarHBondContact O-N 3.23Å
219L73.9Confident70Confident85 Ų8587.9 Ų87.945%0.44543%0.426SS..Hα-helixtrans-63-41.6177.9-73.8179.9000112.6Y215 A216 L222 K223Y215-L219 HydrophobicContact CD1-CD1 3.95Å; Y215-L219 HydrophobicContact CD1-CG 4.4Å; Y215-L219 HydrophobicContact CE1-CD1 3.28Å; Y215-L219 HydrophobicContact CE1-CG 3.94Å; Y215-L219 PolarHBondContact O-N 2.52Å; A216-L219 PolarHBondContact O-N 3.05Å; L219-L222 PolarHBondContact O-N 3.2Å; L219-K223 WeakPolarHBondContact O-CB 3.49Å; L219-K223 PolarHBondContact O-N 2.9Å
220I74.6Confident68.2Low98 Ų9892.9 Ų92.950%0.50344%0.442SS..Hα-helixtrans-63.4-45.2176.7-66.9166.1000110.5A216 L222 K223 Q224A216-I220 VanDerWaalsContact O-CG1 3.31Å; A216-I220 WeakPolarHBondContact O-CG1 3.27Å; A216-I220 PolarHBondContact O-N 3.21Å; I220-L222 VanDerWaalsContact C-N 3.34Å; I220-L222 PolarHBondContact O-N 3.35Å; I220-K223 PolarHBondContact O-N 3.49Å; I220-Q224 HydrophobicContact CG2-CG 4.43Å; I220-Q224 WeakPolarHBondContact O-CB 3.02Å; I220-Q224 VanDerWaalsContact O-CG 3.3Å; I220-Q224 WeakPolarHBondContact O-CG 3.31Å; I220-Q224 PolarHBondContact O-N 2.92Å
221K66.4Low66.1Low110 Ų11099.2 Ų99.248%0.47848%0.475SS..Hα-helixtrans-62-40.4174.6-76.6-175.7177-170.40112.2S217 R218 Q224 Q225S217-K221 WeakPolarHBondContact O-CG 3.3Å; S217-K221 PolarHBondContact O-N 2.74Å; R218-K221 PolarHBondContact O-N 3.45Å; K221-Q224 PolarHBondContact O-N 2.95Å; K221-Q225 WeakPolarHBondContact O-CB 3.24Å; K221-Q225 PolarHBondContact O-N 3.37Å
222L64.9Low64.1Low103 Ų103103.7 Ų103.754%0.53951%0.506SS..Hα-helixtrans-63.8-44.4178-148.289.8000110.8R218 L219 I220 Q225 N226R218-L222 WeakPolarHBondContact O-CB 3.25Å; R218-L222 PolarHBondContact O-N 3.23Å; L219-L222 PolarHBondContact O-N 3.2Å; I220-L222 VanDerWaalsContact C-N 3.34Å; I220-L222 PolarHBondContact O-N 3.35Å; L222-Q225 PolarHBondContact O-N 3.09Å; L222-N226 WeakPolarHBondContact O-CB 3.4Å; L222-N226 PolarHBondContact O-N 3.27Å
223K68.1Low62.7Low137 Ų137102 Ų10260%0.59651%0.507SS*.Hα-helixtrans-63.7-45.8176.1-172.4174.9176.6179.50111.5L219 I220 Q225 N226 E227L219-K223 WeakPolarHBondContact O-CB 3.49Å; L219-K223 PolarHBondContact O-N 2.9Å; I220-K223 PolarHBondContact O-N 3.49Å; K223-Q225 PolarHBondContact O-N 3.22Å; K223-N226 PolarHBondContact O-N 3.41Å; K223-E227 WeakPolarHBondContact CE-OE1 3.24Å; K223-E227 WeakPolarHBondContact CG-OE1 3.49Å; K223-E227 WeakPolarHBondContact O-CB 3.11Å; K223-E227 VanDerWaalsContact O-CG 3.31Å; K223-E227 WeakPolarHBondContact O-CG 3.28Å; K223-E227 PolarHBondContact O-N 2.74Å
224Q63.2Low62.2Low104 Ų10497.5 Ų97.549%0.48649%0.492SS..Hα-helixtrans-64.9-36.1176.2-74.6175.1-100112.9I220 K221 N228I220-Q224 HydrophobicContact CG2-CG 4.43Å; I220-Q224 WeakPolarHBondContact O-CB 3.02Å; I220-Q224 VanDerWaalsContact O-CG 3.3Å; I220-Q224 WeakPolarHBondContact O-CG 3.31Å; I220-Q224 PolarHBondContact O-N 2.92Å; K221-Q224 PolarHBondContact O-N 2.95Å; Q224-N228 WeakPolarHBondContact O-CB 3.28Å; Q224-N228 PolarHBondContact O-N 3.02Å; Q224-N228 PolarHBondContact O-ND2 3.43Å
225Q51.3Low62.3Low123 Ų12397.3 Ų97.358%0.57549%0.491SS*.Hα-helixtrans-67.5-37.9172.4-87.2-171.6-900112.1K221 L222 K223 K229K221-Q225 WeakPolarHBondContact O-CB 3.24Å; K221-Q225 PolarHBondContact O-N 3.37Å; L222-Q225 PolarHBondContact O-N 3.09Å; K223-Q225 PolarHBondContact O-N 3.22Å; Q225-K229 WeakPolarHBondContact O-CB 3.29Å; Q225-K229 WeakPolarHBondContact O-CG 3.39Å; Q225-K229 PolarHBondContact O-N 3.11Å
226N54.9Low62.5Low116 Ų11695.6 Ų95.662%0.6249%0.485SS*.Hα-helixtrans-68.7-42.2177.7-144.530.5000111.2L222 K223 K229 Q230L222-N226 WeakPolarHBondContact O-CB 3.4Å; L222-N226 PolarHBondContact O-N 3.27Å; K223-N226 PolarHBondContact O-N 3.41Å; N226-K229 PolarHBondContact O-N 3.32Å; N226-Q230 PolarHBondContact O-N 2.82Å; N226-Q230 VanDerWaalsContact O-N 3.07Å
227E53.5Low62.4Low90 Ų9098.4 Ų98.442%0.42149%0.49SS..Hα-helixtrans-64.7-41.6174.1-71.5169.417700111.5K223 Q230 L231K223-E227 WeakPolarHBondContact CE-OE1 3.24Å; K223-E227 WeakPolarHBondContact CG-OE1 3.49Å; K223-E227 WeakPolarHBondContact O-CB 3.11Å; K223-E227 VanDerWaalsContact O-CG 3.31Å; K223-E227 WeakPolarHBondContact O-CG 3.28Å; K223-E227 PolarHBondContact O-N 2.74Å; E227-Q230 PolarHBondContact O-N 3.47Å; E227-L231 WeakPolarHBondContact O-CD1 3.46Å; E227-L231 PolarHBondContact O-N 3.02Å
228N45.4Very low62.7Low111 Ų11199.6 Ų99.659%0.59450%0.496SS*.Hα-helixtrans-70.7-28.8176.1-76.6-12.1000113.6Q224Q224-N228 WeakPolarHBondContact O-CB 3.28Å; Q224-N228 PolarHBondContact O-N 3.02Å; Q224-N228 PolarHBondContact O-ND2 3.43Å
229K48.7Very low63.2Low139 Ų13991.6 Ų91.660%0.60447%0.466SS*.Hα-helixtrans-70.5-38.6171.3-81.7179.9179.2-178.90111.8Q225 N226 L231 S232 G233Q225-K229 WeakPolarHBondContact O-CB 3.29Å; Q225-K229 WeakPolarHBondContact O-CG 3.39Å; Q225-K229 PolarHBondContact O-N 3.11Å; N226-K229 PolarHBondContact O-N 3.32Å; K229-L231 PolarHBondContact O-N 2.98Å; K229-S232 PolarHBondContact O-N 3.35Å; K229-S232 VanDerWaalsContact O-N 3.12Å; K229-G233 PolarHBondContact O-N 2.87Å
230Q45.6Very low63.5Low154 Ų15489.6 Ų89.672%0.7246%0.455SS*.Hα-helixtrans-62.6-27.9175-108.3-173.6-1.400113.5N226 E227N226-Q230 PolarHBondContact O-N 2.82Å; N226-Q230 VanDerWaalsContact O-N 3.07Å; E227-Q230 PolarHBondContact O-N 3.47Å
231L42.3Very low63.5Low150 Ų15089.6 Ų89.679%0.78545%0.454SS*.THydrogen-bonded Turntrans-83.5-8.3176.5-79.6149.8000114.1E227 K229E227-L231 WeakPolarHBondContact O-CD1 3.46Å; E227-L231 PolarHBondContact O-N 3.02Å; K229-L231 PolarHBondContact O-N 2.98Å
232S42.2Very low64.1Low94 Ų9488.9 Ų88.966%0.65745%0.45SS*.SBendtrans-126.110.8-172.8-1760000114.1K229K229-S232 PolarHBondContact O-N 3.35Å; K229-S232 VanDerWaalsContact O-N 3.12Å
233G54.5Low64.8Low30 Ų3085.6 Ų85.631%0.30943%0.431SS..  trans-74.2135.8176.400000111.7K229 E237K229-G233 PolarHBondContact O-N 2.87Å; G233-E237 WeakPolarHBondContact CA-OE2 3.33Å
234S70.6Confident64.9Low35 Ų3584 Ų8425%0.24543%0.427CS..  trans-60.6150.7166.767.30000109.8M236 E237 T238S234-M236 PolarHBondContact O-N 3.42Å; S234-E237 PolarHBondContact N-OE2 3.37Å; S234-E237 WeakPolarHBondContact O-CB 3.45Å; S234-E237 PolarHBondContact O-N 3.4Å; S234-E237 VanDerWaalsContact OG-CG 3.27Å; S234-E237 WeakPolarHBondContact OG-CG 3.26Å; S234-E237 PolarHBondContact OG-N 3.27Å; S234-E237 PolarHBondContact OG-OE1 3.01Å; S234-T238 PolarHBondContact O-N 2.98Å; S234-T238 PolarHBondContact O-OG1 2.93Å
235Y82.3Confident65.3Low50 Ų5084.5 Ų84.520%0.19643%0.433CS..Hα-helixtrans-49.8-37.3178164.4-104.6000111.8L239 R295 A297 D368Y235-L239 HydrophobicContact CE1-CD2 4.14Å; Y235-L239 VanDerWaalsContact O-CB 3.27Å; Y235-L239 WeakPolarHBondContact O-CB 3.48Å; Y235-L239 PolarHBondContact O-N 2.77Å; Y235-R295 HydrophobicContact CE1-CB 4.48Å; Y235-A297 HydrophobicContact CD1-CB 4.34Å; Y235-A297 HydrophobicContact CE1-CB 4.28Å; Y235-D368 WeakPolarHBondContact OH-CB 3.2Å; Y235-D368 PolarHBondContact OH-OD2 3.34Å
236M82.8Confident66.3Low12 Ų1279.8 Ų79.86%0.05941%0.413CS..Hα-helixtrans-65.3-45.9177-57.7179.3-62.100112.1S234 L239 I240 A297S234-M236 PolarHBondContact O-N 3.42Å; M236-L239 PolarHBondContact O-N 3.14Å; M236-I240 WeakPolarHBondContact O-CB 3.44Å; M236-I240 WeakPolarHBondContact O-CD1 3.44Å; M236-I240 WeakPolarHBondContact O-CG1 3.29Å; M236-I240 PolarHBondContact O-N 2.95Å; M236-A297 HydrophobicContact CG-CB 4.05Å; M236-A297 HydrophobicContact SD-CB 4.22Å
237E77.5Confident66.8Low103 Ų10380 Ų8048%0.48141%0.414SS..Hα-helixtrans-61.1-45.7175.8-75.8154.6-135.400111.7G233 S234 L239 I240 E241G233-E237 WeakPolarHBondContact CA-OE2 3.33Å; S234-E237 PolarHBondContact N-OE2 3.37Å; S234-E237 WeakPolarHBondContact O-CB 3.45Å; S234-E237 PolarHBondContact O-N 3.4Å; S234-E237 VanDerWaalsContact OG-CG 3.27Å; S234-E237 WeakPolarHBondContact OG-CG 3.26Å; S234-E237 PolarHBondContact OG-N 3.27Å; S234-E237 PolarHBondContact OG-OE1 3.01Å; E237-L239 VanDerWaalsContact C-N 3.31Å; E237-L239 PolarHBondContact O-N 3.27Å; E237-I240 PolarHBondContact O-N 2.96Å; E237-E241 VanDerWaalsContact O-CB 3.28Å; E237-E241 WeakPolarHBondContact O-CB 3.48Å; E237-E241 PolarHBondContact O-N 3.27Å
238T82.8Confident67.6Low70 Ų7077.1 Ų77.143%0.42940%0.404SS..Hα-helixtrans-63-40.1177.6-510000111.4S234 K242S234-T238 PolarHBondContact O-N 2.98Å; S234-T238 PolarHBondContact O-OG1 2.93Å; T238-K242 WeakPolarHBondContact O-CB 3.1Å; T238-K242 PolarHBondContact O-N 3.04Å
239L81.6Confident68.8Low10 Ų1071.9 Ų71.95%0.05238%0.376CS..Hα-helixtrans-68.5-41178-173.262.3000111.9Y235 M236 E237 W243 V252 L253 L299 V366 V374Y235-L239 HydrophobicContact CE1-CD2 4.14Å; Y235-L239 VanDerWaalsContact O-CB 3.27Å; Y235-L239 WeakPolarHBondContact O-CB 3.48Å; Y235-L239 PolarHBondContact O-N 2.77Å; M236-L239 PolarHBondContact O-N 3.14Å; E237-L239 VanDerWaalsContact C-N 3.31Å; E237-L239 PolarHBondContact O-N 3.27Å; L239-W243 VanDerWaalsContact O-CB 3.22Å; L239-W243 WeakPolarHBondContact O-CB 3.4Å; L239-W243 PolarHBondContact O-N 3.45Å; L239-V252 HydrophobicContact CD1-CG1 3.9Å; L239-L253 HydrophobicContact CD1-CD2 4.19Å; L239-L253 HydrophobicContact CD2-CD2 3.9Å; L239-L253 HydrophobicContact CG-CD2 4.12Å; L239-L299 HydrophobicContact CD2-CD1 4.18Å; L239-V366 HydrophobicContact CD2-CG1 3.75Å; L239-V374 HydrophobicContact CD1-CG2 4.17Å
240I79.6Confident70Confident42 Ų4268.7 Ų68.722%0.21536%0.363CS..Hα-helixtrans-63.4-48.1174.5-70.2164.8000110.2M236 E237 K242 W243 M244 L299M236-I240 WeakPolarHBondContact O-CB 3.44Å; M236-I240 WeakPolarHBondContact O-CD1 3.44Å; M236-I240 WeakPolarHBondContact O-CG1 3.29Å; M236-I240 PolarHBondContact O-N 2.95Å; E237-I240 PolarHBondContact O-N 2.96Å; I240-K242 PolarHBondContact O-N 3.48Å; I240-W243 PolarHBondContact O-N 3.42Å; I240-M244 HydrophobicContact CG2-CG 4.12Å; I240-M244 HydrophobicContact CG2-SD 3.66Å; I240-M244 VanDerWaalsContact O-CB 3.3Å; I240-M244 WeakPolarHBondContact O-CB 3.5Å; I240-M244 VanDerWaalsContact O-CG 3.27Å; I240-M244 WeakPolarHBondContact O-CG 3.26Å; I240-M244 PolarHBondContact O-N 3.4Å; I240-L299 HydrophobicContact CD1-CD1 4.15Å; I240-L299 HydrophobicContact CD1-CG 4.19Å; I240-L299 WeakPolarHBondContact CD1-O 3.4Å; I240-L299 HydrophobicContact CG1-CD1 3.68Å; I240-L299 HydrophobicContact CG1-CD2 4.48Å; I240-L299 HydrophobicContact CG1-CG 3.93Å
241E74.9Confident71.6Confident99 Ų9967.7 Ų67.746%0.46336%0.356SS..Hα-helixtrans-60.5-46.7179.3-175.4179.7-172.200110.7E237 W243 M244 N245E237-E241 VanDerWaalsContact O-CB 3.28Å; E237-E241 WeakPolarHBondContact O-CB 3.48Å; E237-E241 PolarHBondContact O-N 3.27Å; E241-W243 VanDerWaalsContact C-N 3.34Å; E241-W243 PolarHBondContact O-N 3.47Å; E241-M244 PolarHBondContact O-N 2.95Å; E241-N245 WeakPolarHBondContact CG-ND2 3.43Å; E241-N245 VanDerWaalsContact O-CB 3.25Å; E241-N245 WeakPolarHBondContact O-CB 3.21Å; E241-N245 VanDerWaalsContact O-CG 3.3Å; E241-N245 PolarHBondContact O-N 3.41Å; E241-N245 PolarHBondContact O-ND2 3.49Å
242K80.2Confident73.5Confident95 Ų9560.8 Ų60.841%0.41332%0.32SS..Hα-helixtrans-61.2-42.5176.2-173.1173.2-178.7175.70111.8T238 I240 S246 V252 E372T238-K242 WeakPolarHBondContact O-CB 3.1Å; T238-K242 PolarHBondContact O-N 3.04Å; I240-K242 PolarHBondContact O-N 3.48Å; K242-S246 WeakPolarHBondContact O-CB 3.49Å; K242-S246 PolarHBondContact O-N 3.32Å; K242-V252 HydrophobicContact CB-CG1 4.36Å; K242-V252 HydrophobicContact CD-CG1 4.28Å; K242-V252 HydrophobicContact CG-CG1 4.03Å; K242-V252 HydrophobicContact CG-CG2 4.17Å; K242-E372 WeakPolarHBondContact CE-OE1 3.36Å; K242-E372 WeakPolarHBondContact CE-OE2 3.38Å; K242-E372 IonicContact NZ-OE1 3.9Å; K242-E372 PolarHBondContact NZ-OE1 3.2Å; K242-E372 IonicContact NZ-OE2 2.9Å; K242-E372 PolarHBondContact NZ-OE2 2.82Å
243W78.3Confident75.5Confident34 Ų3456.6 Ų56.613%0.12929%0.29CS..Hα-helixtrans-67.8-40.5177.717973.4000112.4L239 I240 E241 P249 V252 L253 R431L239-W243 VanDerWaalsContact O-CB 3.22Å; L239-W243 WeakPolarHBondContact O-CB 3.4Å; L239-W243 PolarHBondContact O-N 3.45Å; I240-W243 PolarHBondContact O-N 3.42Å; E241-W243 VanDerWaalsContact C-N 3.34Å; E241-W243 PolarHBondContact O-N 3.47Å; W243-P249 HydrophobicContact CG-CB 4.49Å; W243-V252 HydrophobicContact CB-CB 4.41Å; W243-V252 HydrophobicContact CB-CG1 4.01Å; W243-L253 HydrophobicContact CB-CD1 4.15Å; W243-L253 HydrophobicContact CB-CG 4.43Å; W243-L253 HydrophobicContact CD2-CD1 4.04Å; W243-L253 HydrophobicContact CG-CD1 3.71Å; W243-L253 HydrophobicContact CG-CG 4.13Å; W243-R431 HydrophobicContact CH2-CG 4.27Å; W243-R431 HydrophobicContact CZ2-CB 4.47Å; W243-R431 HydrophobicContact CZ2-CG 3.87Å
244M70.9Confident76.9Confident102 Ų10256.5 Ų56.550%0.50229%0.285SS..Hα-helixtrans-69.4-36.8179.2-77.2-176.454.600113I240 E241 R431I240-M244 HydrophobicContact CG2-CG 4.12Å; I240-M244 HydrophobicContact CG2-SD 3.66Å; I240-M244 VanDerWaalsContact O-CB 3.3Å; I240-M244 WeakPolarHBondContact O-CB 3.5Å; I240-M244 VanDerWaalsContact O-CG 3.27Å; I240-M244 WeakPolarHBondContact O-CG 3.26Å; I240-M244 PolarHBondContact O-N 3.4Å; E241-M244 PolarHBondContact O-N 2.95Å; M244-R431 PolarHBondContact O-NH1 3.12Å
245N71.4Confident77.4Confident115 Ų11559 Ų5962%0.61529%0.293SS*.Hα-helixtrans-92.3-11.1-176.4-65.5-30.5000113.4E241E241-N245 WeakPolarHBondContact CG-ND2 3.43Å; E241-N245 VanDerWaalsContact O-CB 3.25Å; E241-N245 WeakPolarHBondContact O-CB 3.21Å; E241-N245 VanDerWaalsContact O-CG 3.3Å; E241-N245 PolarHBondContact O-N 3.41Å; E241-N245 PolarHBondContact O-ND2 3.49Å
246S73.3Confident77.4Confident24 Ų2461.1 Ų61.117%0.16831%0.314CS..  trans-72.6136176.6-179.70000111.6K242 S248K242-S246 WeakPolarHBondContact O-CB 3.49Å; K242-S246 PolarHBondContact O-N 3.32Å; S246-S248 PolarHBondContact O-N 3.48Å; S246-S248 VanDerWaalsContact OG-C 3.23Å; S246-S248 PolarHBondContact OG-N 2.9Å; S246-S248 VanDerWaalsContact OG-N 3.08Å; S246-S248 PolarHBondContact OG-O 3.43Å
247L64.8Low77.6Confident120 Ų12061.3 Ų61.363%0.62832%0.315SS*.SBendtrans-73.5-13.4169.9-63.1175.4000112.7S427L247-S427 WeakPolarHBondContact O-CB 3.3Å
248S69.8Low77.9Confident31 Ų3164.7 Ų64.722%0.21733%0.331CS..  trans-130.477.4174.348.80000109.7S246 E250 K251S246-S248 PolarHBondContact O-N 3.48Å; S246-S248 VanDerWaalsContact OG-C 3.23Å; S246-S248 PolarHBondContact OG-N 2.9Å; S246-S248 VanDerWaalsContact OG-N 3.08Å; S246-S248 PolarHBondContact OG-O 3.43Å; S248-E250 PolarHBondContact O-N 2.84Å; S248-K251 WeakPolarHBondContact O-CB 3.45Å; S248-K251 PolarHBondContact O-N 3.37Å; S248-K251 VanDerWaalsContact O-N 3.09Å; S248-K251 WeakPolarHBondContact OG-CD 3.49Å
249P70.8Confident77.8Confident1 Ų162.6 Ų62.61%0.00632%0.323CS..G310 helixtrans-60.2-30.9-175.6-2435.6000113.4W243 K251 V252 L253 R431W243-P249 HydrophobicContact CG-CB 4.49Å; P249-K251 PolarHBondContact O-N 3.37Å; P249-V252 PolarHBondContact O-N 3.16Å; P249-L253 PolarHBondContact O-N 3.37Å; P249-R431 HydrophobicContact CB-CG 4.03Å; P249-R431 HydrophobicContact CG-CG 3.85Å
250E73.2Confident78.1Confident72 Ų7262.7 Ų62.734%0.33632%0.324SS..G310 helixtrans-64.8-21.3176.169.9-74.6173.500113.7S248 V252 L253 P373 I430S248-E250 PolarHBondContact O-N 2.84Å; E250-V252 VanDerWaalsContact C-N 3.32Å; E250-L253 WeakPolarHBondContact CA-O 3.41Å; E250-P373 WeakPolarHBondContact O-CB 3.27Å; E250-I430 HydrophobicContact CB-CG2 4.06Å; E250-I430 WeakPolarHBondContact OE2-CD1 3.44Å; E250-I430 WeakPolarHBondContact OE2-CG2 3.27Å
251K79.4Confident78.6Confident133 Ų13366.6 Ų66.658%0.57834%0.34SS*.G310 helixtrans-83.1-11.1172.9-61.8-172.9-170.8167.90112.8S248 P249 P373S248-K251 WeakPolarHBondContact O-CB 3.45Å; S248-K251 PolarHBondContact O-N 3.37Å; S248-K251 VanDerWaalsContact O-N 3.09Å; S248-K251 WeakPolarHBondContact OG-CD 3.49Å; P249-K251 PolarHBondContact O-N 3.37Å; K251-P373 VanDerWaalsContact O-CA 3.3Å; K251-P373 WeakPolarHBondContact O-CA 2.99Å; K251-P373 WeakPolarHBondContact O-CB 3.36Å
252V82.5Confident79.3Confident4 Ų463.7 Ų63.72%0.02433%0.329CS..THydrogen-bonded Turntrans-99.6-49.8175.8-175.60000110.3L239 K242 W243 P249 E250 V374L239-V252 HydrophobicContact CD1-CG1 3.9Å; K242-V252 HydrophobicContact CB-CG1 4.36Å; K242-V252 HydrophobicContact CD-CG1 4.28Å; K242-V252 HydrophobicContact CG-CG1 4.03Å; K242-V252 HydrophobicContact CG-CG2 4.17Å; W243-V252 HydrophobicContact CB-CB 4.41Å; W243-V252 HydrophobicContact CB-CG1 4.01Å; P249-V252 PolarHBondContact O-N 3.16Å; E250-V252 VanDerWaalsContact C-N 3.32Å; V252-V374 PolarHBondContact O-N 3.22Å
253L84.6Confident79.7Confident6 Ų663.8 Ų63.83%0.03133%0.33CS..EExtended strand (participates in β ladder)trans-126.4130176.7-67.3178.4000110.2L239 W243 P249 E250 L299 V366 V374 M376L239-L253 HydrophobicContact CD1-CD2 4.19Å; L239-L253 HydrophobicContact CD2-CD2 3.9Å; L239-L253 HydrophobicContact CG-CD2 4.12Å; W243-L253 HydrophobicContact CB-CD1 4.15Å; W243-L253 HydrophobicContact CB-CG 4.43Å; W243-L253 HydrophobicContact CD2-CD1 4.04Å; W243-L253 HydrophobicContact CG-CD1 3.71Å; W243-L253 HydrophobicContact CG-CG 4.13Å; P249-L253 PolarHBondContact O-N 3.37Å; E250-L253 WeakPolarHBondContact CA-O 3.41Å; L253-L299 HydrophobicContact CD1-CD2 3.95Å; L253-V366 HydrophobicContact CD2-CG1 4.39Å; L253-V366 HydrophobicContact CD2-CG2 4.48Å; L253-V374 WeakPolarHBondContact CA-O 3.13Å; L253-V374 HydrophobicContact CD2-CB 4.02Å; L253-M376 HydrophobicContact CB-CG 4.44Å; L253-M376 HydrophobicContact CB-SD 3.92Å; L253-M376 HydrophobicContact CD1-SD 4.38Å
254S83Confident80.2Confident28 Ų2865.5 Ų65.520%0.19634%0.34CS..EExtended strand (participates in β ladder)trans-136.3144.5177.7-177.10000112C256 V374 L375 M376S254-C256 WeakPolarHBondContact CB-O 3.44Å; S254-C256 PolarHBondContact O-N 3.23Å; S254-C256 PolarHBondContact OG-N 3.16Å; S254-C256 PolarHBondContact OG-O 3.49Å; S254-V374 PolarHBondContact N-O 2.97Å; S254-L375 CarbonylContact O-C 3.53Å; S254-L375 WeakPolarHBondContact O-CA 3.36Å; S254-M376 PolarHBondContact O-N 3.44Å
255E81.1Confident80.8Confident87 Ų8766.3 Ų66.341%0.40735%0.346SS..SBendtrans-73.5-19.1174.9-61.8-173.6170.700112.9L375 M376 Q377 R378E255-L375 WeakPolarHBondContact O-CD1 3.42Å; E255-M376 WeakPolarHBondContact CA-O 3.36Å; E255-M376 HydrophobicContact CG-CE 3.58Å; E255-M376 HydrophobicContact CG-CG 4.26Å; E255-Q377 PolarHBondContact O-NE2 2.81Å; E255-Q377 VanDerWaalsContact O-NE2 3.13Å; E255-R378 IonicContact OE1-NH1 3.78Å
256C83.5Confident81.5Confident96 Ų9662.4 Ų62.465%0.64933%0.327SS*.  trans-140.3135.9178.4-176.20000110S254S254-C256 WeakPolarHBondContact CB-O 3.44Å; S254-C256 PolarHBondContact O-N 3.23Å; S254-C256 PolarHBondContact OG-N 3.16Å; S254-C256 PolarHBondContact OG-O 3.49Å
257I86.3Confident81.6Confident15 Ų1566.9 Ų66.98%0.07735%0.349CS..  trans-126.6143.5176.565.6171.5000109.5G259 V260 F369 P373 L375I257-G259 PolarHBondContact O-N 2.85Å; I257-V260 HydrophobicContact CD1-CB 4.02Å; I257-V260 HydrophobicContact CD1-CG2 3.58Å; I257-V260 HydrophobicContact CG1-CB 3.68Å; I257-V260 HydrophobicContact CG1-CG2 3.72Å; I257-V260 PolarHBondContact O-N 2.81Å; I257-F369 HydrophobicContact CD1-CD2 3.6Å; I257-F369 HydrophobicContact CD1-CE2 3.81Å; I257-P373 HydrophobicContact CG2-CG 4.09Å; I257-P373 WeakPolarHBondContact CG2-O 3.42Å; I257-L375 HydrophobicContact CD1-CB 3.91Å; I257-L375 HydrophobicContact CG1-CB 4.25Å; I257-L375 HydrophobicContact CG1-CD1 4.36Å; I257-L375 HydrophobicContact CG2-CB 4.17Å; I257-L375 HydrophobicContact CG2-CD1 4.37Å
258E83.8Confident82.2Confident174 Ų17463.4 Ų63.481%0.81333%0.331SS*.THydrogen-bonded Turntrans-60.3132-178.3-172.8178.7-173.600110.5R291E258-R291 PolarHBondContact O-NH1 2.95Å; E258-R291 PolarHBondContact O-NH2 3.13Å
259G81.7Confident82.3Confident26 Ų2663.4 Ų63.427%0.26833%0.331SS..THydrogen-bonded Turntrans818178.800000115.5I257 C287 K288I257-G259 PolarHBondContact O-N 2.85Å; G259-C287 CarbonylContact O-C 3.55Å; G259-C287 WeakPolarHBondContact O-CA 3.46Å; G259-K288 CarbonylContact C-O 3.56Å; G259-K288 WeakPolarHBondContact CA-O 3.45Å; G259-K288 CarbonylContact O-C 3.59Å; G259-K288 PolarHBondContact O-N 3.44Å
260V88.2Confident82.4Confident12 Ų1264.4 Ų64.47%0.07334%0.337CS..EExtended strand (participates in β ladder)trans-126121.2171.7-175.10000110.4I257 L285 T286 C287 F369 L375I257-V260 HydrophobicContact CD1-CB 4.02Å; I257-V260 HydrophobicContact CD1-CG2 3.58Å; I257-V260 HydrophobicContact CG1-CB 3.68Å; I257-V260 HydrophobicContact CG1-CG2 3.72Å; I257-V260 PolarHBondContact O-N 2.81Å; V260-L285 HydrophobicContact CG1-CB 4.31Å; V260-T286 WeakPolarHBondContact CA-O 3.32Å; V260-C287 HydrophobicContact CG2-CB 4.36Å; V260-F369 HydrophobicContact CG1-CE2 4.34Å; V260-F369 HydrophobicContact CG1-CZ 4.11Å; V260-F369 HydrophobicContact CG2-CE2 4.25Å; V260-F369 HydrophobicContact CG2-CZ 4.28Å; V260-L375 HydrophobicContact CG1-CD2 4.15Å
261K88Confident82.4Confident125 Ų12563.3 Ų63.354%0.54334%0.335SS..EExtended strand (participates in β ladder)trans-98.7128.4172.4-169.7-169.4-177.6-157.30109.3E263 L285 T286K261-E263 WeakPolarHBondContact CE-OE1 3.42Å; K261-E263 IonicContact NZ-OE1 3.71Å; K261-E263 PolarHBondContact NZ-OE1 2.81Å; K261-L285 CarbonylContact O-C 3.59Å; K261-L285 WeakPolarHBondContact O-CA 3.16Å; K261-T286 PolarHBondContact N-O 3.26Å; K261-T286 PolarHBondContact O-N 2.95Å
262V89.8Confident82.3Confident37 Ų3758.1 Ų58.122%0.22432%0.315CS..EExtended strand (participates in β ladder)trans-106.5126.1179.4-174.80000109.5F283 L285 L375 Q377V262-F283 HydrophobicContact CG1-CD1 4.36Å; V262-L285 HydrophobicContact CB-CD2 4.24Å; V262-L285 HydrophobicContact CG1-CD2 3.87Å; V262-L285 HydrophobicContact CG2-CD2 3.78Å; V262-L375 HydrophobicContact CG2-CD1 4.22Å; V262-L375 HydrophobicContact CG2-CD2 3.69Å; V262-Q377 HydrophobicContact CG1-CG 4.18Å
263E89.6Confident81.8Confident97 Ų9760.5 Ų60.545%0.45333%0.331SS..EExtended strand (participates in β ladder)trans-120.2151167.9-67.4178-177.600108.5K261 F283 A284K261-E263 WeakPolarHBondContact CE-OE1 3.42Å; K261-E263 IonicContact NZ-OE1 3.71Å; K261-E263 PolarHBondContact NZ-OE1 2.81Å; E263-F283 CarbonylContact O-C 3.59Å; E263-F283 WeakPolarHBondContact O-CA 3.22Å; E263-A284 HydrophobicContact CB-CB 4.24Å; E263-A284 PolarHBondContact N-O 2.97Å; E263-A284 PolarHBondContact O-N 2.85Å
264H88.9Confident81.1Confident71 Ų7163.8 Ų63.833%0.32935%0.352SS..EExtended strand (participates in β ladder)trans-152146.5-171.559.3-40.6000110.1L268 T282 F283H264-L268 VanDerWaalsContact CD2-CD2 3.41Å; H264-L268 WeakPolarHBondContact CD2-CD2 3.38Å; H264-L268 WeakPolarHBondContact CD2-CG 3.3Å; H264-L268 WeakPolarHBondContact NE2-CG 3.4Å; H264-T282 VanDerWaalsContact CA-O 3.27Å; H264-T282 WeakPolarHBondContact CA-O 3.48Å; H264-F283 HydrophobicContact CB-CD1 3.83Å; H264-F283 HydrophobicContact CB-CE1 3.96Å
265N83.4Confident80.2Confident119 Ų11968.4 Ų68.464%0.63637%0.369SS*.EExtended strand (participates in β ladder)trans-149.7128.9176178.643.5000109.3T282N265-T282 PolarHBondContact N-O 3.34Å; N265-T282 PolarHBondContact O-N 3.44Å
266P85.2Confident79.6Confident32 Ų3271.4 Ų71.421%0.20838%0.38CS..SBendcis-71.9-170.6-5.336.2-39.6000112.2V270 T280 W281P266-V270 HydrophobicContact CB-CG2 4.38Å; P266-V270 HydrophobicContact CG-CG2 3.9Å; P266-T280 WeakPolarHBondContact CD-O 3.31Å; P266-W281 HydrophobicContact CG-CG 4.47Å
267D75.9Confident79.1Confident119 Ų11967.2 Ų67.264%0.63635%0.352SS*.  trans-54.7152.5174.2-65.9-35.4000111.9S269 V270 W281D267-S269 PolarHBondContact O-N 3.24Å; D267-S269 VanDerWaalsContact O-N 3.15Å; D267-V270 VanDerWaalsContact O-CG2 3.31Å; D267-V270 WeakPolarHBondContact O-CG2 3.36Å; D267-W281 PolarHBondContact O-NE1 3.36Å
268L76.7Confident79.1Confident46 Ų4672.4 Ų72.424%0.24138%0.375CS..SBendtrans-60-25.3-179.3-68176000113.8H264 F283 R378 V379 M380H264-L268 VanDerWaalsContact CD2-CD2 3.41Å; H264-L268 WeakPolarHBondContact CD2-CD2 3.38Å; H264-L268 WeakPolarHBondContact CD2-CG 3.3Å; H264-L268 WeakPolarHBondContact NE2-CG 3.4Å; L268-F283 HydrophobicContact CD2-CE1 3.75Å; L268-F283 HydrophobicContact CD2-CZ 3.99Å; L268-R378 WeakPolarHBondContact CB-O 3.45Å; L268-V379 HydrophobicContact CD2-CG1 3.83Å; L268-V379 CarbonylContact O-C 3.5Å; L268-V379 WeakPolarHBondContact O-CA 3.27Å; L268-M380 PolarHBondContact O-N 3.19Å
269S72.7Confident79.3Confident32 Ų3266.5 Ų66.522%0.22435%0.348CS..EExtended strand (participates in β ladder)trans-113.3120.7177.4179.40000109.3D267 M380D267-S269 PolarHBondContact O-N 3.24Å; D267-S269 VanDerWaalsContact O-N 3.15Å; S269-M380 VanDerWaalsContact CA-O 3.31Å; S269-M380 WeakPolarHBondContact CA-O 3.49Å; S269-M380 WeakPolarHBondContact OG-CE 3.37Å
270V73.3Confident79.8Confident22 Ų2267.3 Ų67.313%0.13335%0.348CS..EExtended strand (participates in β ladder)trans-128139.6-177.3-177.50000109.7P266 D267 V272 Q279 W281 M380 I381 D382P266-V270 HydrophobicContact CB-CG2 4.38Å; P266-V270 HydrophobicContact CG-CG2 3.9Å; D267-V270 VanDerWaalsContact O-CG2 3.31Å; D267-V270 WeakPolarHBondContact O-CG2 3.36Å; V270-V272 HydrophobicContact CG1-CG1 4.19Å; V270-Q279 HydrophobicContact CG1-CG 4.4Å; V270-W281 HydrophobicContact CB-CZ2 4.24Å; V270-W281 HydrophobicContact CG2-CZ2 3.82Å; V270-M380 PolarHBondContact N-O 3.48Å; V270-I381 HydrophobicContact CB-CD1 4.41Å; V270-I381 HydrophobicContact CB-CG1 4.49Å; V270-I381 HydrophobicContact CG1-CD1 4.42Å; V270-I381 CarbonylContact O-C 3.54Å; V270-I381 VanDerWaalsContact O-CA 3.26Å; V270-I381 WeakPolarHBondContact O-CA 3.41Å; V270-D382 PolarHBondContact O-N 2.98Å
271T73.6Confident80.1Confident49 Ų4966.7 Ų66.730%0.30134%0.344SS..EExtended strand (participates in β ladder)trans-116132.7173.3-51.40000110.1D382 L389T271-D382 CarbonylContact C-O 3.41Å; T271-D382 WeakPolarHBondContact CA-O 3.47Å; T271-D382 HydrophobicContact CG2-CB 4Å; T271-L389 HydrophobicContact CG2-CD1 3.39Å
272V76.8Confident80.4Confident23 Ų2363.8 Ų63.814%0.13934%0.337CS..EExtended strand (participates in β ladder)trans-126.3141-178.7-61.70000110.9V270 S277 I381 D382 A383 A384V270-V272 HydrophobicContact CG1-CG1 4.19Å; V272-S277 WeakPolarHBondContact CG2-OG 3.3Å; V272-I381 HydrophobicContact CG1-CD1 4.04Å; V272-I381 HydrophobicContact CG2-CD1 4.3Å; V272-I381 HydrophobicContact CG2-CG1 4.26Å; V272-D382 PolarHBondContact N-O 2.96Å; V272-A383 HydrophobicContact CG2-CB 3.74Å; V272-A383 WeakPolarHBondContact O-CA 3.23Å; V272-A384 PolarHBondContact O-N 2.72Å
273S71.2Confident80.6Confident54 Ų5462 Ų6238%0.37833%0.326SS..  trans-97.4-2.3-173.754.90000114.7A384S273-A384 CarbonylContact C-O 3.48Å; S273-A384 WeakPolarHBondContact CA-O 3.3Å
274T69.6Low80.8Confident76 Ų7658.4 Ų58.447%0.46631%0.313SS..  trans-115138.5-173.458.70000112.1K276T274-K276 VanDerWaalsContact C-N 3.35Å; T274-K276 PolarHBondContact O-N 3.31Å; T274-K276 PolarHBondContact OG1-O 3.3Å
275K64.5Low80.9Confident125 Ų12555 Ų5554%0.54330%0.297SS..SBendtrans-58.5-44.6177.6-73.2-170.5179.3-179.90112.7S277 T355 E356 F358K275-S277 PolarHBondContact O-N 3.28Å; K275-T355 CarbonylContact O-C 3.47Å; K275-E356 CarbonylContact O-C 3.53Å; K275-E356 VanDerWaalsContact O-C 3.23Å; K275-E356 WeakPolarHBondContact O-CA 3.44Å; K275-F358 HydrophobicContact CB-CE1 4.3Å; K275-F358 HydrophobicContact CB-CZ 4.39Å; K275-F358 HydrophobicContact CD-CD2 4.36Å; K275-F358 HydrophobicContact CD-CE2 3.97Å; K275-F358 HydrophobicContact CD-CZ 4.22Å; K275-F358 HydrophobicContact CG-CD1 3.97Å; K275-F358 HydrophobicContact CG-CD2 3.89Å; K275-F358 HydrophobicContact CG-CE1 3.54Å; K275-F358 HydrophobicContact CG-CE2 3.45Å; K275-F358 VanDerWaalsContact CG-CE2 3.45Å; K275-F358 HydrophobicContact CG-CG 4.14Å; K275-F358 HydrophobicContact CG-CZ 3.26Å
276K68.3Low81.3Confident150 Ų15051 Ų5165%0.65228%0.277SS*.SBendtrans-86.9104.2169.2-67.9-166.9175.5-154.50107.2T274 T355 E356T274-K276 VanDerWaalsContact C-N 3.35Å; T274-K276 PolarHBondContact O-N 3.31Å; T274-K276 PolarHBondContact OG1-O 3.3Å; K276-T355 WeakPolarHBondContact CA-O 3.16Å; K276-E356 WeakPolarHBondContact CE-OE1 3.3Å; K276-E356 HydrophobicContact CG-CG 4.44Å; K276-E356 IonicContact NZ-OE1 3.59Å; K276-E356 PolarHBondContact NZ-OE1 3.15Å; K276-E356 VanDerWaalsContact NZ-OE1 3.08Å
277S73.4Confident81.4Confident7 Ų749.4 Ų49.45%0.04927%0.267CS..EExtended strand (participates in β ladder)trans-130.7133.3176.357.90000109.3V272 K275 N354 T355V272-S277 WeakPolarHBondContact CG2-OG 3.3Å; K275-S277 PolarHBondContact O-N 3.28Å; S277-N354 WeakPolarHBondContact O-CA 3.32Å; S277-N354 PolarHBondContact O-OD1 2.91Å; S277-T355 PolarHBondContact N-O 3.11Å; S277-T355 PolarHBondContact O-N 3.32Å; S277-T355 VanDerWaalsContact O-N 3.16Å; S277-T355 VanDerWaalsContact OG-CG2 3.22Å; S277-T355 WeakPolarHBondContact OG-CG2 3.48Å
278H86.8Confident82Confident124 Ų12449.9 Ų49.957%0.57426%0.263SS*.EExtended strand (participates in β ladder)trans-120.6121.2172.2177.772.2000107.1T280 F353H278-T280 PolarHBondContact NE2-OG1 3.12Å; H278-F353 VanDerWaalsContact CA-O 3.3Å; H278-F353 WeakPolarHBondContact CA-O 3.34Å; H278-F353 PolarHBondContact ND1-O 3.25Å
279Q88Confident82.3Confident50 Ų5051.8 Ų51.823%0.23428%0.278CS..EExtended strand (participates in β ladder)trans-125143.5178-172.2565200109.1V270 W281 A352 F353 I381V270-Q279 HydrophobicContact CG1-CG 4.4Å; Q279-W281 HydrophobicContact CB-CH2 4.3Å; Q279-W281 HydrophobicContact CB-CZ3 4.39Å; Q279-W281 HydrophobicContact CG-CH2 4.01Å; Q279-W281 HydrophobicContact CG-CZ2 4.06Å; Q279-W281 HydrophobicContact CG-CZ3 4.24Å; Q279-A352 CarbonylContact O-C 3.53Å; Q279-A352 WeakPolarHBondContact O-CA 3.31Å; Q279-F353 HydrophobicContact CB-CB 4.5Å; Q279-F353 HydrophobicContact CB-CD1 4.48Å; Q279-F353 PolarHBondContact N-O 2.87Å; Q279-F353 PolarHBondContact O-N 2.75Å; Q279-I381 HydrophobicContact CB-CD1 3.7Å; Q279-I381 HydrophobicContact CG-CD1 4.11Å
280T91.7Very high82.8Confident43 Ų4352.2 Ų52.226%0.26428%0.283SS..EExtended strand (participates in β ladder)trans-125.8134.3174.2-63.80000109.5P266 H278 I310 I351P266-T280 WeakPolarHBondContact CD-O 3.31Å; H278-T280 PolarHBondContact NE2-OG1 3.12Å; T280-I310 HydrophobicContact CG2-CD1 3.67Å; T280-I351 CarbonylContact C-O 3.59Å; T280-I351 VanDerWaalsContact CA-O 3.29Å; T280-I351 WeakPolarHBondContact CA-O 3.37Å
281W94.5Very high83.5Confident0 Ų054 Ų540%029%0.288CS..EExtended strand (participates in β ladder)trans-105.4138.2167.3-67.4-92.8000110.4P266 D267 V270 Q279 F283 F307 G350 I351 F353 V379 I381P266-W281 HydrophobicContact CG-CG 4.47Å; D267-W281 PolarHBondContact O-NE1 3.36Å; V270-W281 HydrophobicContact CB-CZ2 4.24Å; V270-W281 HydrophobicContact CG2-CZ2 3.82Å; Q279-W281 HydrophobicContact CB-CH2 4.3Å; Q279-W281 HydrophobicContact CB-CZ3 4.39Å; Q279-W281 HydrophobicContact CG-CH2 4.01Å; Q279-W281 HydrophobicContact CG-CZ2 4.06Å; Q279-W281 HydrophobicContact CG-CZ3 4.24Å; W281-F283 HydrophobicContact CB-CD2 4.29Å; W281-F283 HydrophobicContact CB-CE2 3.6Å; W281-F283 HydrophobicContact CB-CZ 4.19Å; W281-F283 HydrophobicContact CG-CE2 4.41Å; W281-F307 HydrophobicContact CH2-CE1 4.42Å; W281-F307 HydrophobicContact CZ3-CE1 4.09Å; W281-G350 CarbonylContact O-C 3.46Å; W281-G350 VanDerWaalsContact O-CA 3.31Å; W281-G350 WeakPolarHBondContact O-CA 3.48Å; W281-I351 PolarHBondContact N-O 3.35Å; W281-I351 PolarHBondContact O-N 3.08Å; W281-F353 HydrophobicContact CH2-CB 4.12Å; W281-F353 HydrophobicContact CZ3-CB 3.57Å; W281-F353 HydrophobicContact CZ3-CG 4.49Å; W281-V379 HydrophobicContact CD2-CG1 4.26Å; W281-V379 HydrophobicContact CG-CG1 4.35Å; W281-V379 HydrophobicContact CZ2-CB 4.43Å; W281-I381 HydrophobicContact CH2-CB 3.99Å; W281-I381 HydrophobicContact CH2-CD1 4.05Å; W281-I381 HydrophobicContact CH2-CG2 4.21Å; W281-I381 HydrophobicContact CZ2-CB 4.36Å
282T94.2Very high84.2Confident63 Ų6353.5 Ų53.539%0.38728%0.283SS..EExtended strand (participates in β ladder)trans-114.4116.8170.4-560000109.1H264 N265 V349H264-T282 VanDerWaalsContact CA-O 3.27Å; H264-T282 WeakPolarHBondContact CA-O 3.48Å; N265-T282 PolarHBondContact N-O 3.34Å; N265-T282 PolarHBondContact O-N 3.44Å; T282-V349 CarbonylContact C-O 3.55Å; T282-V349 WeakPolarHBondContact CA-O 3.43Å
283F94.6Very high84.8Confident0 Ų052.5 Ų52.50%028%0.276CS..EExtended strand (participates in β ladder)trans-98120.6174-64.9-91.5000109.7V262 E263 H264 L268 W281 K348 V349 I351 I365 F367 Q377 V379V262-F283 HydrophobicContact CG1-CD1 4.36Å; E263-F283 CarbonylContact O-C 3.59Å; E263-F283 WeakPolarHBondContact O-CA 3.22Å; H264-F283 HydrophobicContact CB-CD1 3.83Å; H264-F283 HydrophobicContact CB-CE1 3.96Å; L268-F283 HydrophobicContact CD2-CE1 3.75Å; L268-F283 HydrophobicContact CD2-CZ 3.99Å; W281-F283 HydrophobicContact CB-CD2 4.29Å; W281-F283 HydrophobicContact CB-CE2 3.6Å; W281-F283 HydrophobicContact CB-CZ 4.19Å; W281-F283 HydrophobicContact CG-CE2 4.41Å; F283-K348 CarbonylContact O-C 3.52Å; F283-K348 VanDerWaalsContact O-CA 3.25Å; F283-K348 WeakPolarHBondContact O-CA 3.36Å; F283-V349 HydrophobicContact CB-CB 4.39Å; F283-V349 PolarHBondContact N-O 2.99Å; F283-V349 PolarHBondContact O-N 3.35Å; F283-I351 HydrophobicContact CD2-CG1 4.12Å; F283-I351 HydrophobicContact CE2-CG1 3.96Å; F283-I365 HydrophobicContact CD2-CD1 4.37Å; F283-I365 HydrophobicContact CE1-CD1 4.45Å; F283-I365 HydrophobicContact CE2-CD1 3.4Å; F283-I365 HydrophobicContact CZ-CD1 3.45Å; F283-I365 VanDerWaalsContact CZ-CD1 3.45Å; F283-F367 HydrophobicContact CB-CZ 4.02Å; F283-F367 HydrophobicContact CD1-CZ 4.23Å; F283-F367 HydrophobicContact CD2-CZ 4.28Å; F283-F367 AromaticContact CG-CZ 3.91Å; F283-F367 HydrophobicContact CG-CZ 3.91Å; F283-Q377 HydrophobicContact CD1-CB 4.43Å; F283-Q377 HydrophobicContact CD1-CG 4.24Å; F283-Q377 HydrophobicContact CE1-CB 3.8Å; F283-Q377 HydrophobicContact CE1-CG 4.04Å; F283-Q377 HydrophobicContact CZ-CB 4.43Å; F283-V379 HydrophobicContact CE2-CG1 4.43Å; F283-V379 HydrophobicContact CZ-CG1 3.69Å
284A92.8Very high85.6Confident21 Ų2154.8 Ų54.817%0.17428%0.278CS..EExtended strand (participates in β ladder)trans-102.4109.3172.200000109.8E263 Y347E263-A284 HydrophobicContact CB-CB 4.24Å; E263-A284 PolarHBondContact N-O 2.97Å; E263-A284 PolarHBondContact O-N 2.85Å; A284-Y347 CarbonylContact C-O 3.54Å; A284-Y347 VanDerWaalsContact CA-O 3.3Å; A284-Y347 WeakPolarHBondContact CA-O 3.48Å
285L92.6Very high86.6Confident0 Ų054.8 Ų54.80%027%0.269CS..EExtended strand (participates in β ladder)trans-100.4117.2179.5-45.6171.2000108.7V260 K261 V262 L293 V346 Y347 F367 F369 L375V260-L285 HydrophobicContact CG1-CB 4.31Å; K261-L285 CarbonylContact O-C 3.59Å; K261-L285 WeakPolarHBondContact O-CA 3.16Å; V262-L285 HydrophobicContact CB-CD2 4.24Å; V262-L285 HydrophobicContact CG1-CD2 3.87Å; V262-L285 HydrophobicContact CG2-CD2 3.78Å; L285-L293 HydrophobicContact CD1-CD2 4.39Å; L285-V346 CarbonylContact O-C 3.55Å; L285-V346 VanDerWaalsContact O-CA 3.29Å; L285-V346 WeakPolarHBondContact O-CA 3.25Å; L285-Y347 PolarHBondContact N-O 3.26Å; L285-Y347 PolarHBondContact O-N 3.02Å; L285-F367 HydrophobicContact CD1-CB 4.21Å; L285-F367 HydrophobicContact CD1-CD1 3.54Å; L285-F367 HydrophobicContact CD1-CE1 3.96Å; L285-F367 HydrophobicContact CD1-CG 3.85Å; L285-F369 HydrophobicContact CD1-CZ 4.05Å; L285-L375 HydrophobicContact CD2-CD2 4.06Å
286T90.3Very high87.9Confident34 Ų3448.8 Ų48.821%0.20924%0.243CC..EExtended strand (participates in β ladder)trans-105.4111.3174.8-57.70000109.7V260 K261 V346V260-T286 WeakPolarHBondContact CA-O 3.32Å; K261-T286 PolarHBondContact N-O 3.26Å; K261-T286 PolarHBondContact O-N 2.95Å; T286-V346 HydrophobicContact CG2-CG2 4.4Å
287C89.1Confident89Confident0 Ų041.8 Ų41.80%021%0.213CC..EExtended strand (participates in β ladder)trans-100.6113.2-176.6-55.40000110.8G259 V260 P289 R291 H344 Y345 F369G259-C287 CarbonylContact O-C 3.55Å; G259-C287 WeakPolarHBondContact O-CA 3.46Å; V260-C287 HydrophobicContact CG2-CB 4.36Å; C287-P289 CarbonylContact C-O 3.57Å; C287-P289 CarbonylContact O-C 3.57Å; C287-R291 HydrophobicContact CB-CB 4.16Å; C287-H344 WeakPolarHBondContact O-CA 3.44Å; C287-H344 VanDerWaalsContact O-CB 3.24Å; C287-H344 WeakPolarHBondContact O-CB 3.19Å; C287-Y345 PolarHBondContact N-O 3.43Å; C287-Y345 PolarHBondContact O-N 3.27Å; C287-Y345 VanDerWaalsContact O-N 3.11Å; C287-F369 WeakPolarHBondContact SG-CE1 3.44Å
288K87Confident89.8Confident129 Ų12941.4 Ų41.456%0.56121%0.21SC*.SBendtrans-131.7107.5176.5-75.9-176.4179.3-169.70109.3G259 H344G259-K288 CarbonylContact C-O 3.56Å; G259-K288 WeakPolarHBondContact CA-O 3.45Å; G259-K288 CarbonylContact O-C 3.59Å; G259-K288 PolarHBondContact O-N 3.44Å; K288-H344 HydrophobicContact CD-CB 4.27Å; K288-H344 HydrophobicContact CG-CB 3.49Å; K288-H344 VanDerWaalsContact CG-CB 3.49Å
289P83.9Confident89.7Confident86 Ų8635.8 Ų35.856%0.55818%0.184SC*.SBendcis-69.2166.2430.3-36.3000113.2C287 R291C287-P289 CarbonylContact C-O 3.57Å; C287-P289 CarbonylContact O-C 3.57Å; P289-R291 PolarHBondContact O-N 3.49Å
290A83.8Confident89.2Confident40 Ų4037.5 Ų37.533%0.33119%0.189SC..  trans-50.3121.7176.100000112.2L342 D343 Y345A290-L342 VanDerWaalsContact CB-O 3.27Å; A290-L342 WeakPolarHBondContact CB-O 3.2Å; A290-D343 PolarHBondContact N-O 2.78Å; A290-Y345 HydrophobicContact CB-CD2 3.66Å; A290-Y345 HydrophobicContact CB-CE2 4.04Å
291R87.4Confident88.4Confident59 Ų5939.3 Ų39.322%0.22320%0.197CC..  trans-129.7142.4176.1-69-176.2-177169.17.9110E258 C287 P289 Y347 F369E258-R291 PolarHBondContact O-NH1 2.95Å; E258-R291 PolarHBondContact O-NH2 3.13Å; C287-R291 HydrophobicContact CB-CB 4.16Å; P289-R291 PolarHBondContact O-N 3.49Å; R291-Y347 WeakPolarHBondContact O-CE2 3.24Å; R291-Y347 PolarHBondContact O-OH 3.01Å; R291-F369 HydrophobicContact CB-CD1 4.02Å
292M87.4Confident87.2Confident40 Ų4043.4 Ų43.420%0.19723%0.231CC..  trans-88.5129.3179.1-165.6165.870.900110.9Y294 Y347 F369M292-Y294 HydrophobicContact CB-CE2 4.21Å; M292-Y294 HydrophobicContact CE-CD1 3.8Å; M292-Y294 HydrophobicContact CE-CE1 3.11Å; M292-Y294 HydrophobicContact CE-CE2 4.07Å; M292-Y294 WeakPolarHBondContact CE-OH 3.44Å; M292-Y294 WeakPolarHBondContact O-CD2 3.38Å; M292-Y347 WeakPolarHBondContact CA-OH 3.42Å; M292-F369 WeakPolarHBondContact O-CA 3.43Å
293L89.4Confident86.1Confident1 Ų142.8 Ų42.81%0.00522%0.224CC..  trans-81.9113.1171.4-173.666.4000109.4L285 V296 W332 Y347 V349 F367 F369L285-L293 HydrophobicContact CD1-CD2 4.39Å; L293-V296 HydrophobicContact CD1-CG2 4.35Å; L293-V296 HydrophobicContact CD2-CG2 3.61Å; L293-V296 HydrophobicContact CG-CG2 4.12Å; L293-W332 HydrophobicContact CD2-CZ3 4.28Å; L293-W332 HydrophobicContact CG-CZ3 4.24Å; L293-Y347 HydrophobicContact CB-CD1 3.88Å; L293-Y347 HydrophobicContact CB-CD2 4.16Å; L293-Y347 HydrophobicContact CB-CE1 3.56Å; L293-Y347 HydrophobicContact CB-CE2 3.85Å; L293-Y347 HydrophobicContact CB-CG 4.18Å; L293-Y347 HydrophobicContact CD2-CD1 3.83Å; L293-Y347 HydrophobicContact CD2-CE1 4.35Å; L293-Y347 HydrophobicContact CD2-CG 3.95Å; L293-Y347 PolarHBondContact N-OH 3.48Å; L293-Y347 VanDerWaalsContact N-OH 3.08Å; L293-V349 HydrophobicContact CD2-CG2 4.42Å; L293-F367 HydrophobicContact CD1-CB 3.88Å; L293-F369 HydrophobicContact CB-CD1 4.24Å; L293-F369 HydrophobicContact CB-CE1 4.01Å; L293-F369 HydrophobicContact CD1-CD1 4.11Å; L293-F369 HydrophobicContact CD1-CD2 4.48Å; L293-F369 HydrophobicContact CD1-CE1 3.8Å; L293-F369 HydrophobicContact CD1-CE2 4.21Å; L293-F369 HydrophobicContact CD1-CG 4.45Å; L293-F369 HydrophobicContact CD1-CZ 3.87Å; L293-F369 HydrophobicContact CG-CE1 4.48Å
294Y88.8Confident85.3Confident103 Ų10348.1 Ų48.140%0.40424%0.244SC..  trans-90.9-36.5-178.9-70.5-89.1000112.6M292 G334 D368 F369M292-Y294 HydrophobicContact CB-CE2 4.21Å; M292-Y294 HydrophobicContact CE-CD1 3.8Å; M292-Y294 HydrophobicContact CE-CE1 3.11Å; M292-Y294 HydrophobicContact CE-CE2 4.07Å; M292-Y294 WeakPolarHBondContact CE-OH 3.44Å; M292-Y294 WeakPolarHBondContact O-CD2 3.38Å; Y294-G334 PolarHBondContact O-N 3.12Å; Y294-D368 PolarHBondContact N-O 3.47Å; Y294-F369 VanDerWaalsContact CD2-C 3.42Å; Y294-F369 WeakPolarHBondContact CD2-O 3.47Å; Y294-F369 WeakPolarHBondContact CE2-O 3.21Å
295R90.6Very high84.8Confident75 Ų7552.6 Ų52.628%0.28327%0.271SS..EExtended strand (participates in β ladder)trans-143.3149.2179.9-52.5179178.7-102.3-5112.5Y235 E331 W332 D368Y235-R295 HydrophobicContact CE1-CB 4.48Å; R295-E331 IonicContact CZ-OE1 3.62Å; R295-E331 IonicContact NH1-OE1 2.65Å; R295-E331 PolarHBondContact NH1-OE1 2.95Å; R295-W332 CarbonylContact C-O 3.57Å; R295-W332 VanDerWaalsContact CA-O 3.24Å; R295-W332 WeakPolarHBondContact CA-O 3.37Å; R295-D368 HydrophobicContact CB-CB 3.92Å; R295-D368 PolarHBondContact N-O 3.47Å; R295-D368 VanDerWaalsContact N-O 3.17Å; R295-D368 PolarHBondContact O-N 3.24Å
296V92.1Very high84.4Confident0 Ų054.5 Ų54.50%028%0.28CS..EExtended strand (participates in β ladder)trans-128.5126.4164.3-177.60000107.5L293 I309 I312 E331 W332 V349 I365 V366 F367L293-V296 HydrophobicContact CD1-CG2 4.35Å; L293-V296 HydrophobicContact CD2-CG2 3.61Å; L293-V296 HydrophobicContact CG-CG2 4.12Å; V296-I309 HydrophobicContact CB-CD1 4.25Å; V296-I309 HydrophobicContact CG1-CD1 3.91Å; V296-I309 WeakPolarHBondContact O-CD1 3.41Å; V296-I312 HydrophobicContact CB-CD1 4.1Å; V296-I312 HydrophobicContact CG2-CD1 3.94Å; V296-E331 CarbonylContact O-C 3.56Å; V296-E331 WeakPolarHBondContact O-CA 3.41Å; V296-W332 HydrophobicContact CB-CB 4.38Å; V296-W332 HydrophobicContact CB-CE3 4.4Å; V296-W332 HydrophobicContact CG2-CE3 3.97Å; V296-W332 HydrophobicContact CG2-CZ3 4.43Å; V296-W332 PolarHBondContact N-O 3.5Å; V296-W332 PolarHBondContact O-N 3.29Å; V296-V349 HydrophobicContact CG1-CG1 4.03Å; V296-V349 HydrophobicContact CG2-CG2 4.35Å; V296-I365 HydrophobicContact CG1-CG2 4.24Å; V296-V366 CarbonylContact C-O 3.55Å; V296-V366 VanDerWaalsContact CA-O 3.28Å; V296-V366 WeakPolarHBondContact CA-O 3.41Å; V296-F367 HydrophobicContact CG1-CD1 4.08Å; V296-F367 HydrophobicContact CG1-CE1 4.06Å; V296-F367 HydrophobicContact CG2-CD1 3.96Å; V296-F367 HydrophobicContact CG2-CE1 4.49Å
297A91.2Very high84.4Confident2 Ų253 Ų532%0.01727%0.271CS..EExtended strand (participates in β ladder)trans-138.7150.5-177.700000112.4Y235 M236 Q330 E331 V366Y235-A297 HydrophobicContact CD1-CB 4.34Å; Y235-A297 HydrophobicContact CE1-CB 4.28Å; M236-A297 HydrophobicContact CG-CB 4.05Å; M236-A297 HydrophobicContact SD-CB 4.22Å; A297-Q330 WeakPolarHBondContact CA-O 3.39Å; A297-E331 HydrophobicContact CB-CG 4.38Å; A297-V366 PolarHBondContact N-O 2.97Å; A297-V366 PolarHBondContact O-N 2.85Å
298L89.4Confident84.5Confident0 Ų053.8 Ų53.80%028%0.276CS..EExtended strand (participates in β ladder)trans-95.8107.4170.9-61.5-178000108.8Y300 F307 I309 Q330 I351 Q363 I365L298-Y300 PolarHBondContact O-N 2.84Å; L298-F307 HydrophobicContact CD1-CB 3.72Å; L298-I309 HydrophobicContact CD1-CG1 4.48Å; L298-I309 HydrophobicContact CG-CG1 4.27Å; L298-Q330 PolarHBondContact N-O 3.06Å; L298-I351 HydrophobicContact CD2-CD1 4.32Å; L298-I351 HydrophobicContact CD2-CG2 4.43Å; L298-Q363 HydrophobicContact CB-CG 4.28Å; L298-Q363 HydrophobicContact CD2-CG 3.96Å; L298-I365 HydrophobicContact CD2-CB 4.42Å; L298-I365 HydrophobicContact CD2-CG1 3.69Å; L298-I365 HydrophobicContact CD2-CG2 4.47Å
299L84.1Confident84.8Confident5 Ų547.8 Ų47.83%0.02625%0.25CC..  trans-64.9-39.2-162.2-166.861.8000113.9L239 I240 L253 T364 V366L239-L299 HydrophobicContact CD2-CD1 4.18Å; I240-L299 HydrophobicContact CD1-CD1 4.15Å; I240-L299 HydrophobicContact CD1-CG 4.19Å; I240-L299 WeakPolarHBondContact CD1-O 3.4Å; I240-L299 HydrophobicContact CG1-CD1 3.68Å; I240-L299 HydrophobicContact CG1-CD2 4.48Å; I240-L299 HydrophobicContact CG1-CG 3.93Å; L253-L299 HydrophobicContact CD1-CD2 3.95Å; L299-T364 HydrophobicContact CB-CG2 4.28Å; L299-T364 WeakPolarHBondContact CB-O 3.22Å; L299-T364 HydrophobicContact CD2-CG2 3.98Å; L299-T364 PolarHBondContact N-O 2.73Å; L299-V366 HydrophobicContact CB-CG2 4.04Å; L299-V366 HydrophobicContact CD1-CG2 4.14Å; L299-V366 HydrophobicContact CD2-CG2 4.27Å; L299-V366 HydrophobicContact CG-CG2 4.39Å
300Y78.1Confident85.3Confident87 Ų8747.6 Ų47.634%0.34124%0.243SC..  trans-105.7135.8-173.6-60.2-57.8000112.7L298 Q363 T364L298-Y300 PolarHBondContact O-N 2.84Å; Y300-Q363 VanDerWaalsContact N-OE1 3.11Å; Y300-Q363 PolarHBondContact O-NE2 2.99Å; Y300-Q363 PolarHBondContact O-OE1 3.41Å; Y300-T364 WeakPolarHBondContact CE2-OG1 3.49Å
301D74.6Confident85.6Confident81 Ų8147.7 Ų47.743%0.43324%0.244SC..G310 helixtrans-83.4-10.3178.3-88.3-26.9000114.5H303 R304D301-H303 PolarHBondContact O-N 3.45Å; D301-R304 WeakPolarHBondContact O-CB 3.14Å; D301-R304 PolarHBondContact O-N 2.68Å; D301-R304 VanDerWaalsContact O-N 3.09Å; D301-R304 WeakPolarHBondContact OD1-CD 3.3Å; D301-R304 IonicContact OD1-CZ 2.68Å; D301-R304 IonicContact OD1-NE 2.75Å; D301-R304 IonicContact OD1-NH1 2.74Å; D301-R304 PolarHBondContact OD1-NH1 2.73Å; D301-R304 IonicContact OD2-NH1 3.95Å; D301-R304 PolarHBondContact OD2-NH1 3.24Å
302A70.1Confident85.9Confident85 Ų8544.9 Ų44.970%0.70223%0.234SC*.G310 helixtrans-55-31.1-172.900000114.2
303H70.9Confident86Confident51 Ų5144 Ų4424%0.23623%0.232CC..G310 helixtrans-12528.1179.9-57.1-60000112.7D301 P305 H306 F307 F361 R362D301-H303 PolarHBondContact O-N 3.45Å; H303-P305 VanDerWaalsContact C-N 3.32Å; H303-P305 VanDerWaalsContact O-N 3.16Å; H303-H306 WeakPolarHBondContact O-CB 3.42Å; H303-H306 PolarHBondContact O-N 3.14Å; H303-F307 HydrophobicContact CB-CD2 3.94Å; H303-F307 HydrophobicContact CB-CE2 3.89Å; H303-F307 PolarHBondContact O-N 3.18Å; H303-F361 HydrophobicContact CB-CD1 4.25Å; H303-F361 AromaticContact CE1-CD1 3.96Å; H303-F361 AromaticContact CG-CD1 3.83Å; H303-F361 AromaticContact ND1-CD1 3.53Å; H303-R362 PolarHBondContact CD2-O 3.46Å
304R77.9Confident85.9Confident111 Ų11144 Ų4442%0.41923%0.232SC..THydrogen-bonded Turntrans-48.3-39.7-177.4-168.3-177.7-174.2125-3.9115.2D301 H306 Q330D301-R304 WeakPolarHBondContact O-CB 3.14Å; D301-R304 PolarHBondContact O-N 2.68Å; D301-R304 VanDerWaalsContact O-N 3.09Å; D301-R304 WeakPolarHBondContact OD1-CD 3.3Å; D301-R304 IonicContact OD1-CZ 2.68Å; D301-R304 IonicContact OD1-NE 2.75Å; D301-R304 IonicContact OD1-NH1 2.74Å; D301-R304 PolarHBondContact OD1-NH1 2.73Å; D301-R304 IonicContact OD2-NH1 3.95Å; D301-R304 PolarHBondContact OD2-NH1 3.24Å; R304-H306 PolarHBondContact O-N 3.34Å; R304-Q330 HydrophobicContact CG-CG 4.03Å
305P81.7Confident85.7Confident115 Ų11539.6 Ų39.675%0.74722%0.217SC*.THydrogen-bonded Turntrans-67.3-18.8178.8-20.734.1000114H303H303-P305 VanDerWaalsContact C-N 3.32Å; H303-P305 VanDerWaalsContact O-N 3.16Å
306H85.3Confident85Confident41 Ų4137.6 Ų37.619%0.1921%0.212CC..THydrogen-bonded Turntrans-96-28.7-172.4-61.6-64.3000113.1H303 R304 F353 N354 F361H303-H306 WeakPolarHBondContact O-CB 3.42Å; H303-H306 PolarHBondContact O-N 3.14Å; R304-H306 PolarHBondContact O-N 3.34Å; H306-F353 HydrophobicContact CB-CD2 3.84Å; H306-F353 HydrophobicContact CB-CE2 3.6Å; H306-F353 CarbonylContact O-C 3.23Å; H306-F353 WeakPolarHBondContact O-CA 3.34Å; H306-N354 WeakPolarHBondContact CA-O 3.5Å; H306-N354 WeakPolarHBondContact CB-O 3.46Å; H306-N354 PolarHBondContact ND1-O 3.19Å; H306-N354 PolarHBondContact O-N 2.91Å; H306-F361 AromaticContact CD2-CD1 3.82Å; H306-F361 AromaticContact CD2-CE1 3.47Å; H306-F361 VanDerWaalsContact CD2-CE1 3.47Å; H306-F361 WeakPolarHBondContact CD2-CE1 3.4Å; H306-F361 AromaticContact CG-CE1 3.94Å; H306-F361 AromaticContact NE2-CE1 3.59Å
307F89.6Confident83.9Confident2 Ų241.8 Ų41.81%0.00924%0.242CC..EExtended strand (participates in β ladder)trans-109.1143.3-177.8-67.2-87.7000111.4W281 L298 H303 Q330 I351 A352 F353 F361 Q363 V379 I381W281-F307 HydrophobicContact CH2-CE1 4.42Å; W281-F307 HydrophobicContact CZ3-CE1 4.09Å; L298-F307 HydrophobicContact CD1-CB 3.72Å; H303-F307 HydrophobicContact CB-CD2 3.94Å; H303-F307 HydrophobicContact CB-CE2 3.89Å; H303-F307 PolarHBondContact O-N 3.18Å; F307-Q330 PolarHBondContact O-NE2 2.88Å; F307-I351 HydrophobicContact CD1-CG2 4.47Å; F307-A352 CarbonylContact C-O 3.51Å; F307-A352 VanDerWaalsContact CA-O 3.31Å; F307-A352 WeakPolarHBondContact CA-O 3.26Å; F307-F353 HydrophobicContact CD1-CB 4.06Å; F307-F353 AromaticContact CD1-CD2 3.94Å; F307-F353 HydrophobicContact CD1-CD2 3.94Å; F307-F353 HydrophobicContact CD1-CG 4.49Å; F307-F353 HydrophobicContact CD2-CD2 4.1Å; F307-F353 HydrophobicContact CE1-CB 3.96Å; F307-F353 AromaticContact CE1-CD2 3.54Å; F307-F353 HydrophobicContact CE1-CD2 3.54Å; F307-F353 HydrophobicContact CE1-CE2 4.44Å; F307-F353 HydrophobicContact CE1-CG 4.12Å; F307-F353 AromaticContact CE2-CD2 3.73Å; F307-F353 HydrophobicContact CE2-CD2 3.73Å; F307-F353 AromaticContact CE2-CE2 3.97Å; F307-F353 HydrophobicContact CE2-CE2 3.97Å; F307-F353 HydrophobicContact CG-CD2 4.21Å; F307-F353 AromaticContact CZ-CD2 3.43Å; F307-F353 HydrophobicContact CZ-CD2 3.43Å; F307-F353 VanDerWaalsContact CZ-CD2 3.43Å; F307-F353 AromaticContact CZ-CE2 3.88Å; F307-F353 HydrophobicContact CZ-CE2 3.88Å; F307-F353 HydrophobicContact CZ-CG 4.36Å; F307-F361 HydrophobicContact CE2-CB 3.87Å; F307-F361 HydrophobicContact CZ-CB 3.94Å; F307-Q363 HydrophobicContact CB-CG 4.43Å; F307-Q363 HydrophobicContact CD1-CB 4.06Å; F307-Q363 HydrophobicContact CD1-CG 4.33Å; F307-Q363 HydrophobicContact CD2-CB 3.94Å; F307-Q363 HydrophobicContact CD2-CG 4.26Å; F307-Q363 HydrophobicContact CE1-CB 3.94Å; F307-Q363 HydrophobicContact CE2-CB 3.81Å; F307-Q363 HydrophobicContact CG-CB 4.05Å; F307-Q363 HydrophobicContact CG-CG 4.1Å; F307-Q363 HydrophobicContact CZ-CB 3.82Å; F307-V379 HydrophobicContact CE1-CG2 4.07Å; F307-I381 HydrophobicContact CZ-CG2 4.2Å
308S91.9Very high82.8Confident17 Ų1747.7 Ų47.712%0.11928%0.278CS..EExtended strand (participates in β ladder)trans-151.9151.3171.1560000111.7I351 A352S308-I351 CarbonylContact O-C 3.19Å; S308-I351 WeakPolarHBondContact O-CA 3.25Å; S308-A352 PolarHBondContact N-O 2.92Å; S308-A352 PolarHBondContact O-N 3.17Å
309I93.3Very high82.1Confident2 Ų251.3 Ų51.31%0.0130%0.3CS..EExtended strand (participates in β ladder)trans-81.2122.7168.6-54.4169.6000106.9V296 L298 I312 V325 C329 W332 I351V296-I309 HydrophobicContact CB-CD1 4.25Å; V296-I309 HydrophobicContact CG1-CD1 3.91Å; V296-I309 WeakPolarHBondContact O-CD1 3.41Å; L298-I309 HydrophobicContact CD1-CG1 4.48Å; L298-I309 HydrophobicContact CG-CG1 4.27Å; I309-I312 HydrophobicContact CG2-CD1 3.8Å; I309-I312 HydrophobicContact CG2-CG1 3.98Å; I309-V325 HydrophobicContact CB-CG1 4.43Å; I309-V325 HydrophobicContact CG2-CG1 4.06Å; I309-V325 VanDerWaalsContact O-CG1 3.29Å; I309-V325 WeakPolarHBondContact O-CG1 3.38Å; I309-C329 HydrophobicContact CB-CB 4.16Å; I309-C329 WeakPolarHBondContact CB-O 3.48Å; I309-C329 PolarHBondContact N-O 3.19Å; I309-W332 HydrophobicContact CD1-CB 4.34Å; I309-I351 HydrophobicContact CB-CD1 4.27Å; I309-I351 HydrophobicContact CG1-CD1 3.75Å; I309-I351 HydrophobicContact CG2-CD1 4.34Å
310I93.1Very high82.1Confident82 Ų8254 Ų5442%0.42131%0.312SS..EExtended strand (participates in β ladder)trans-112.1-23.9-174.155.2157.2000113.8T280 G350 A352T280-I310 HydrophobicContact CG2-CD1 3.67Å; I310-G350 VanDerWaalsContact CG1-O 3.28Å; I310-G350 WeakPolarHBondContact CG1-O 3.23Å; I310-G350 PolarHBondContact N-O 3.49Å; I310-A352 HydrophobicContact CB-CB 4.45Å; I310-A352 HydrophobicContact CD1-CB 4.16Å; I310-A352 HydrophobicContact CG1-CB 4.24Å; I310-A352 HydrophobicContact CG2-CB 3.42Å; I310-A352 VanDerWaalsContact CG2-CB 3.42Å
311A91.6Very high82.3Confident42 Ų4254.1 Ų54.135%0.34732%0.322SS..EExtended strand (participates in β ladder)trans-155.1137-176.900000110.5V349 G350A311-V349 CarbonylContact O-C 3.44Å; A311-V349 WeakPolarHBondContact O-CA 3.47Å; A311-G350 PolarHBondContact N-O 3.36Å; A311-G350 PolarHBondContact O-N 3.25Å
312I92.1Very high82.8Confident0 Ų054.7 Ų54.70%033%0.332CS..EExtended strand (participates in β ladder)trans-134.2131.3168.7-67.9175000106.7V296 I309 Q323 V325 W332 K348 V349V296-I312 HydrophobicContact CB-CD1 4.1Å; V296-I312 HydrophobicContact CG2-CD1 3.94Å; I309-I312 HydrophobicContact CG2-CD1 3.8Å; I309-I312 HydrophobicContact CG2-CG1 3.98Å; I312-Q323 HydrophobicContact CB-CB 4.24Å; I312-Q323 HydrophobicContact CG2-CB 4.21Å; I312-Q323 HydrophobicContact CG2-CG 4.06Å; I312-Q323 WeakPolarHBondContact O-CB 3.44Å; I312-Q323 PolarHBondContact O-N 2.7Å; I312-V325 HydrophobicContact CB-CG2 4.04Å; I312-V325 HydrophobicContact CD1-CG2 4.46Å; I312-V325 HydrophobicContact CG1-CG2 4.15Å; I312-W332 HydrophobicContact CD1-CB 3.5Å; I312-W332 VanDerWaalsContact CD1-CB 3.5Å; I312-W332 HydrophobicContact CD1-CD2 3.26Å; I312-W332 HydrophobicContact CD1-CE3 3.6Å; I312-W332 HydrophobicContact CD1-CG 3.23Å; I312-W332 HydrophobicContact CD1-CZ3 4.37Å; I312-W332 HydrophobicContact CG1-CD2 4.48Å; I312-W332 HydrophobicContact CG2-CD2 4.42Å; I312-W332 HydrophobicContact CG2-CE3 4.5Å; I312-W332 HydrophobicContact CG2-CH2 3.96Å; I312-W332 HydrophobicContact CG2-CZ2 3.91Å; I312-W332 HydrophobicContact CG2-CZ3 4.27Å; I312-K348 CarbonylContact C-O 3.22Å; I312-K348 WeakPolarHBondContact CA-O 3.44Å; I312-V349 HydrophobicContact CG1-CG1 4.1Å; I312-V349 HydrophobicContact CG1-CG2 4.26Å
313S90.5Very high83.6Confident22 Ų2252.8 Ų52.815%0.15431%0.309CS..EExtended strand (participates in β ladder)trans-135.1150173.154.20000109.9Q320 V321 Y347 K348S313-Q320 PolarHBondContact OG-OE1 3.42Å; S313-V321 VanDerWaalsContact CA-O 3.28Å; S313-V321 WeakPolarHBondContact CA-O 3.31Å; S313-Y347 CarbonylContact O-C 3.49Å; S313-Y347 VanDerWaalsContact O-CA 3.28Å; S313-Y347 WeakPolarHBondContact O-CA 3.43Å; S313-K348 PolarHBondContact N-O 3.14Å; S313-K348 PolarHBondContact O-N 3.1Å; S313-K348 WeakPolarHBondContact OG-CB 3.16Å; S313-K348 PolarHBondContact OG-O 2.95Å
314A88.2Confident84.2Confident2 Ų259 Ų592%0.01734%0.338CS..EExtended strand (participates in β ladder)trans-143.4150.9-179.500000111.3V321 M337 V346 Y347A314-V321 PolarHBondContact N-O 2.7Å; A314-V321 PolarHBondContact O-N 2.7Å; A314-M337 HydrophobicContact CB-CE 3.27Å; A314-M337 HydrophobicContact CB-SD 3.62Å; A314-V346 WeakPolarHBondContact CA-O 3.41Å; A314-Y347 HydrophobicContact CB-CD1 3.43Å; A314-Y347 VanDerWaalsContact CB-CD1 3.43Å; A314-Y347 HydrophobicContact CB-CE1 3.34Å; A314-Y347 HydrophobicContact CB-CG 4.45Å
315G82.9Confident84.6Confident9 Ų955.4 Ų55.49%0.09333%0.328CS..EExtended strand (participates in β ladder)trans158.7-146.617200000110.6T319 V346G315-T319 CarbonylContact C-O 3.57Å; G315-T319 VanDerWaalsContact CA-O 3.27Å; G315-T319 WeakPolarHBondContact CA-O 3.29Å; G315-V346 PolarHBondContact N-O 2.82Å; G315-V346 PolarHBondContact O-N 3.45Å
316D77Confident84.6Confident33 Ų3354 Ų5418%0.17632%0.319CS..  trans-94.5-178.9173.571.346.3000111.1T318 T319 Q320 L342D316-T318 PolarHBondContact O-N 3.07Å; D316-T318 VanDerWaalsContact O-N 3.17Å; D316-T318 VanDerWaalsContact OD1-CA 3.25Å; D316-T318 WeakPolarHBondContact OD1-CA 3.35Å; D316-T318 WeakPolarHBondContact OD1-CB 3.42Å; D316-T318 PolarHBondContact OD1-N 3.26Å; D316-T318 PolarHBondContact OD1-OG1 3.41Å; D316-T319 PolarHBondContact N-O 3.07Å; D316-T319 PolarHBondContact OD1-N 3.31Å; D316-T319 PolarHBondContact OD1-OG1 2.75Å; D316-T319 PolarHBondContact OD2-OG1 3.08Å; D316-Q320 PolarHBondContact O-NE2 3.16Å; D316-L342 HydrophobicContact CB-CD2 4.31Å
317S69.4Low84.2Confident89 Ų8960.9 Ų60.962%0.62235%0.351SS*.SBendtrans-64-19.1-178-49.60000113.8H344S317-H344 PolarHBondContact OG-NE2 3.45Å
318T67.5Low83.7Confident125 Ų12566.9 Ų66.977%0.76738%0.384SS*.SBendtrans-112.7-25.3-17554.80000114D316D316-T318 PolarHBondContact O-N 3.07Å; D316-T318 VanDerWaalsContact O-N 3.17Å; D316-T318 VanDerWaalsContact OD1-CA 3.25Å; D316-T318 WeakPolarHBondContact OD1-CA 3.35Å; D316-T318 WeakPolarHBondContact OD1-CB 3.42Å; D316-T318 PolarHBondContact OD1-N 3.26Å; D316-T318 PolarHBondContact OD1-OG1 3.41Å
319T75.6Confident83.3Confident77 Ų7766.5 Ų66.547%0.47238%0.381SS..  trans-124.2109.6-179.468.40000109G315 D316G315-T319 CarbonylContact C-O 3.57Å; G315-T319 VanDerWaalsContact CA-O 3.27Å; G315-T319 WeakPolarHBondContact CA-O 3.29Å; D316-T319 PolarHBondContact N-O 3.07Å; D316-T319 PolarHBondContact OD1-N 3.31Å; D316-T319 PolarHBondContact OD1-OG1 2.75Å; D316-T319 PolarHBondContact OD2-OG1 3.08Å
320Q82.1Confident82.9Confident61 Ų6167.2 Ų67.229%0.28538%0.384SS..EExtended strand (participates in β ladder)trans-116.2123.9178.8-72.9-74.9-5700108.8S313 D316 V346S313-Q320 PolarHBondContact OG-OE1 3.42Å; D316-Q320 PolarHBondContact O-NE2 3.16Å; Q320-V346 PolarHBondContact NE2-O 3.13Å; Q320-V346 VanDerWaalsContact NE2-O 3.08Å
321V83.8Confident82.8Confident90 Ų9066.1 Ų66.155%0.54538%0.377SS..EExtended strand (participates in β ladder)trans-105117.8178.7-176.40000108.9S313 A314 Q323S313-V321 VanDerWaalsContact CA-O 3.28Å; S313-V321 WeakPolarHBondContact CA-O 3.31Å; A314-V321 PolarHBondContact N-O 2.7Å; A314-V321 PolarHBondContact O-N 2.7Å; V321-Q323 PolarHBondContact O-NE2 2.73Å
322S85.4Confident82.7Confident93 Ų9364.7 Ų64.765%0.6536%0.363SS*.EExtended strand (participates in β ladder)trans-66.5137.5175-163.70000110.6
323Q86.3Confident82.4Confident44 Ų4469.7 Ų69.721%0.20639%0.388CS..EExtended strand (participates in β ladder)trans-97.1151.7173.7-59.4-58.8-64.200109.6I312 V321 V325 W332 M337I312-Q323 HydrophobicContact CB-CB 4.24Å; I312-Q323 HydrophobicContact CG2-CB 4.21Å; I312-Q323 HydrophobicContact CG2-CG 4.06Å; I312-Q323 WeakPolarHBondContact O-CB 3.44Å; I312-Q323 PolarHBondContact O-N 2.7Å; V321-Q323 PolarHBondContact O-NE2 2.73Å; Q323-V325 PolarHBondContact O-N 3.47Å; Q323-W332 HydrophobicContact CB-CZ2 3.87Å; Q323-W332 HydrophobicContact CG-CH2 4.49Å; Q323-W332 HydrophobicContact CG-CZ2 3.79Å; Q323-M337 HydrophobicContact CG-CE 3.69Å
324E83.6Confident82Confident183 Ų18369.4 Ų69.486%0.85539%0.389SS*.PPolyproline II helixtrans-68.9127.4171.5-68.2-179.3173.500109.3W332E324-W332 PolarHBondContact O-NE1 3.39Å
325V86.4Confident81Confident35 Ų3570.8 Ų70.821%0.21240%0.403CS..  trans-125.6120.2176.7-1780000107.4I309 I312 Q323 C329I309-V325 HydrophobicContact CB-CG1 4.43Å; I309-V325 HydrophobicContact CG2-CG1 4.06Å; I309-V325 VanDerWaalsContact O-CG1 3.29Å; I309-V325 WeakPolarHBondContact O-CG1 3.38Å; I312-V325 HydrophobicContact CB-CG2 4.04Å; I312-V325 HydrophobicContact CD1-CG2 4.46Å; I312-V325 HydrophobicContact CG1-CG2 4.15Å; Q323-V325 PolarHBondContact O-N 3.47Å; V325-C329 HydrophobicContact CG1-CB 3.72Å
326P81.2Confident80Confident84 Ų8480.1 Ų80.155%0.54544%0.441SS..  trans-61156175.6-23.233.5000112.7C329P326-C329 HydrophobicContact CB-CB 4.39Å; P326-C329 WeakPolarHBondContact O-CB 3.22Å; P326-C329 PolarHBondContact O-N 3.32Å
327E76.2Confident79.3Confident186 Ų18680.6 Ų80.687%0.86944%0.443SS*.THydrogen-bonded Turntrans-62.3139.1171.2-69.5-174.7173.800111.1C329E327-C329 PolarHBondContact O-N 3.36Å
328N79Confident78.6Confident129 Ų12979.8 Ų79.869%0.6944%0.442SS*.THydrogen-bonded Turntrans54.631.1-177.1-58.9-40.9000114.4Q330N328-Q330 PolarHBondContact O-N 3.04Å; N328-Q330 PolarHBondContact O-NE2 2.69Å
329C85Confident78Confident9 Ų982.5 Ų82.56%0.06145%0.446CS..BIsolated β-bridgetrans-59.3125.8-179177.90000111.9I309 V325 P326 E327 E331I309-C329 HydrophobicContact CB-CB 4.16Å; I309-C329 WeakPolarHBondContact CB-O 3.48Å; I309-C329 PolarHBondContact N-O 3.19Å; V325-C329 HydrophobicContact CG1-CB 3.72Å; P326-C329 HydrophobicContact CB-CB 4.39Å; P326-C329 WeakPolarHBondContact O-CB 3.22Å; P326-C329 PolarHBondContact O-N 3.32Å; E327-C329 PolarHBondContact O-N 3.36Å; C329-E331 PolarHBondContact SG-O 3.38Å
330Q85.2Confident77Confident16 Ų1684 Ų848%0.07545%0.451CS..SBendtrans-104.2-25.9173.5-60.3-62-54.200112.2A297 L298 R304 F307 N328A297-Q330 WeakPolarHBondContact CA-O 3.39Å; L298-Q330 PolarHBondContact N-O 3.06Å; R304-Q330 HydrophobicContact CG-CG 4.03Å; F307-Q330 PolarHBondContact O-NE2 2.88Å; N328-Q330 PolarHBondContact O-N 3.04Å; N328-Q330 PolarHBondContact O-NE2 2.69Å
331E89.1Confident75.9Confident59 Ų5985.3 Ų85.328%0.27648%0.48SS..EExtended strand (participates in β ladder)trans-135.8122.6176.8-177.4-178.1-174.900108.3R295 V296 A297 C329 I333R295-E331 IonicContact CZ-OE1 3.62Å; R295-E331 IonicContact NH1-OE1 2.65Å; R295-E331 PolarHBondContact NH1-OE1 2.95Å; V296-E331 CarbonylContact O-C 3.56Å; V296-E331 WeakPolarHBondContact O-CA 3.41Å; A297-E331 HydrophobicContact CB-CG 4.38Å; C329-E331 PolarHBondContact SG-O 3.38Å; E331-I333 HydrophobicContact CG-CG1 4.36Å
332W89.6Confident75Confident13 Ų1383.6 Ų83.65%0.04947%0.468CS..EExtended strand (participates in β ladder)trans-106.7135170.4176.787000109.7L293 R295 V296 I309 I312 Q323 E324 G334L293-W332 HydrophobicContact CD2-CZ3 4.28Å; L293-W332 HydrophobicContact CG-CZ3 4.24Å; R295-W332 CarbonylContact C-O 3.57Å; R295-W332 VanDerWaalsContact CA-O 3.24Å; R295-W332 WeakPolarHBondContact CA-O 3.37Å; V296-W332 HydrophobicContact CB-CB 4.38Å; V296-W332 HydrophobicContact CB-CE3 4.4Å; V296-W332 HydrophobicContact CG2-CE3 3.97Å; V296-W332 HydrophobicContact CG2-CZ3 4.43Å; V296-W332 PolarHBondContact N-O 3.5Å; V296-W332 PolarHBondContact O-N 3.29Å; I309-W332 HydrophobicContact CD1-CB 4.34Å; I312-W332 HydrophobicContact CD1-CB 3.5Å; I312-W332 VanDerWaalsContact CD1-CB 3.5Å; I312-W332 HydrophobicContact CD1-CD2 3.26Å; I312-W332 HydrophobicContact CD1-CE3 3.6Å; I312-W332 HydrophobicContact CD1-CG 3.23Å; I312-W332 HydrophobicContact CD1-CZ3 4.37Å; I312-W332 HydrophobicContact CG1-CD2 4.48Å; I312-W332 HydrophobicContact CG2-CD2 4.42Å; I312-W332 HydrophobicContact CG2-CE3 4.5Å; I312-W332 HydrophobicContact CG2-CH2 3.96Å; I312-W332 HydrophobicContact CG2-CZ2 3.91Å; I312-W332 HydrophobicContact CG2-CZ3 4.27Å; Q323-W332 HydrophobicContact CB-CZ2 3.87Å; Q323-W332 HydrophobicContact CG-CH2 4.49Å; Q323-W332 HydrophobicContact CG-CZ2 3.79Å; E324-W332 PolarHBondContact O-NE1 3.39Å; W332-G334 VanDerWaalsContact CZ3-CA 3.49Å
333I86.5Confident74.5Confident104 Ų10486 Ų8653%0.53347%0.474SS..EExtended strand (participates in β ladder)trans-114.9116.4177.4-55.5174.8000108.2E331E331-I333 HydrophobicContact CG-CG1 4.36Å
334G81.6Confident74.3Confident16 Ų1686 Ų8617%0.16547%0.474CS..  trans-94.3-158.6177.500000114Y294 W332Y294-G334 PolarHBondContact O-N 3.12Å; W332-G334 VanDerWaalsContact CZ3-CA 3.49Å
335G66.8Low74.3Confident31 Ų3178.4 Ų78.432%0.3244%0.437SS..  trans102.46.2171.400000116.7
336K62.1Low74.4Confident206 Ų20677.3 Ų77.390%0.89643%0.431SS*.  trans-94.225.1176.7-63.3-176.3-177.8174.20114.1
337M62.8Low74.9Confident42 Ų4273.4 Ų73.421%0.20741%0.405CS..  trans-96.4135-178.9-66.9177-176.100110.8A314 Q323 Q339A314-M337 HydrophobicContact CB-CE 3.27Å; A314-M337 HydrophobicContact CB-SD 3.62Å; Q323-M337 HydrophobicContact CG-CE 3.69Å; M337-Q339 PolarHBondContact O-N 2.67Å
338A55.3Low75.7Confident72 Ų7269 Ų6960%0.59538%0.383SS*.  trans-63.1133.516900000108.9N340A338-N340 PolarHBondContact O-N 3.2Å
339Q55.2Low76.4Confident182 Ų18262.9 Ų62.985%0.8535%0.35SS*.  trans-67.983.4169.4-70.1-166.6-3.100108.7M337M337-Q339 PolarHBondContact O-N 2.67Å
340N53.9Low76.8Confident109 Ų10962.7 Ų62.758%0.58335%0.35SS*.  trans-70.2134.7162.5-65.4-10.1000105.7A338 L342A338-N340 PolarHBondContact O-N 3.2Å; N340-L342 HydrophobicContact CB-CD1 4.38Å; N340-L342 HydrophobicContact CB-CG 4.15Å; N340-L342 PolarHBondContact O-N 2.63Å
341G58.5Low77.3Confident88 Ų8862 Ų6291%0.90735%0.346SS*.  trans-66.454.5-177.800000113.7
342L65.4Low77.5Confident54 Ų5459.4 Ų59.428%0.28334%0.335SS..  trans-79.4135.3176.7-64.9171.8000108.9A290 D316 N340 H344 Y345A290-L342 VanDerWaalsContact CB-O 3.27Å; A290-L342 WeakPolarHBondContact CB-O 3.2Å; D316-L342 HydrophobicContact CB-CD2 4.31Å; N340-L342 HydrophobicContact CB-CD1 4.38Å; N340-L342 HydrophobicContact CB-CG 4.15Å; N340-L342 PolarHBondContact O-N 2.63Å; L342-H344 PolarHBondContact O-N 3.49Å; L342-Y345 HydrophobicContact CD1-CD1 4.31Å; L342-Y345 HydrophobicContact CD1-CE1 3.81Å
343D74.9Confident77.6Confident145 Ų14558.8 Ų58.878%0.77533%0.333SS*.SBendtrans-69.9-21.9174.9-67.8-25.4000112.3A290A290-D343 PolarHBondContact N-O 2.78Å
344H80.9Confident77.7Confident43 Ų4358.1 Ų58.120%0.19933%0.33CS..  trans-149.8152.9-179.769.3-93000112.9C287 K288 S317 L342C287-H344 WeakPolarHBondContact O-CA 3.44Å; C287-H344 VanDerWaalsContact O-CB 3.24Å; C287-H344 WeakPolarHBondContact O-CB 3.19Å; K288-H344 HydrophobicContact CD-CB 4.27Å; K288-H344 HydrophobicContact CG-CB 3.49Å; K288-H344 VanDerWaalsContact CG-CB 3.49Å; S317-H344 PolarHBondContact OG-NE2 3.45Å; L342-H344 PolarHBondContact O-N 3.49Å
345Y85.5Confident77.9Confident24 Ų2457.4 Ų57.49%0.09432%0.323CS..EExtended strand (participates in β ladder)trans-111.8141.2170.2-88.1-74.6000110.7C287 A290 L342 Y347C287-Y345 PolarHBondContact N-O 3.43Å; C287-Y345 PolarHBondContact O-N 3.27Å; C287-Y345 VanDerWaalsContact O-N 3.11Å; A290-Y345 HydrophobicContact CB-CD2 3.66Å; A290-Y345 HydrophobicContact CB-CE2 4.04Å; L342-Y345 HydrophobicContact CD1-CD1 4.31Å; L342-Y345 HydrophobicContact CD1-CE1 3.81Å; Y345-Y347 HydrophobicContact CG-CE2 4.28Å
346V88.4Confident78.6Confident12 Ų1261.8 Ų61.87%0.07334%0.335CS..EExtended strand (participates in β ladder)trans-118.2119.1169.7-175.90000108.8L285 T286 A314 G315 Q320L285-V346 CarbonylContact O-C 3.55Å; L285-V346 VanDerWaalsContact O-CA 3.29Å; L285-V346 WeakPolarHBondContact O-CA 3.25Å; T286-V346 HydrophobicContact CG2-CG2 4.4Å; A314-V346 WeakPolarHBondContact CA-O 3.41Å; G315-V346 PolarHBondContact N-O 2.82Å; G315-V346 PolarHBondContact O-N 3.45Å; Q320-V346 PolarHBondContact NE2-O 3.13Å; Q320-V346 VanDerWaalsContact NE2-O 3.08Å
347Y91.3Very high79.2Confident1 Ų156.6 Ų56.60%0.00432%0.316CS..EExtended strand (participates in β ladder)trans-104.6137.5172.8-62.9-85.3000110.1A284 L285 R291 M292 L293 S313 A314 Y345 F369A284-Y347 CarbonylContact C-O 3.54Å; A284-Y347 VanDerWaalsContact CA-O 3.3Å; A284-Y347 WeakPolarHBondContact CA-O 3.48Å; L285-Y347 PolarHBondContact N-O 3.26Å; L285-Y347 PolarHBondContact O-N 3.02Å; R291-Y347 WeakPolarHBondContact O-CE2 3.24Å; R291-Y347 PolarHBondContact O-OH 3.01Å; M292-Y347 WeakPolarHBondContact CA-OH 3.42Å; L293-Y347 HydrophobicContact CB-CD1 3.88Å; L293-Y347 HydrophobicContact CB-CD2 4.16Å; L293-Y347 HydrophobicContact CB-CE1 3.56Å; L293-Y347 HydrophobicContact CB-CE2 3.85Å; L293-Y347 HydrophobicContact CB-CG 4.18Å; L293-Y347 HydrophobicContact CD2-CD1 3.83Å; L293-Y347 HydrophobicContact CD2-CE1 4.35Å; L293-Y347 HydrophobicContact CD2-CG 3.95Å; L293-Y347 PolarHBondContact N-OH 3.48Å; L293-Y347 VanDerWaalsContact N-OH 3.08Å; S313-Y347 CarbonylContact O-C 3.49Å; S313-Y347 VanDerWaalsContact O-CA 3.28Å; S313-Y347 WeakPolarHBondContact O-CA 3.43Å; A314-Y347 HydrophobicContact CB-CD1 3.43Å; A314-Y347 VanDerWaalsContact CB-CD1 3.43Å; A314-Y347 HydrophobicContact CB-CE1 3.34Å; A314-Y347 HydrophobicContact CB-CG 4.45Å; Y345-Y347 HydrophobicContact CG-CE2 4.28Å; Y347-F369 HydrophobicContact CD2-CE1 4.31Å; Y347-F369 HydrophobicContact CE2-CE1 4.2Å
348K92.2Very high79.8Confident95 Ų9557.6 Ų57.641%0.41332%0.32SS..EExtended strand (participates in β ladder)trans-117.5121.8165.5-54.4177.4178.1178.80109.9F283 I312 S313F283-K348 CarbonylContact O-C 3.52Å; F283-K348 VanDerWaalsContact O-CA 3.25Å; F283-K348 WeakPolarHBondContact O-CA 3.36Å; I312-K348 CarbonylContact C-O 3.22Å; I312-K348 WeakPolarHBondContact CA-O 3.44Å; S313-K348 PolarHBondContact N-O 3.14Å; S313-K348 PolarHBondContact O-N 3.1Å; S313-K348 WeakPolarHBondContact OG-CB 3.16Å; S313-K348 PolarHBondContact OG-O 2.95Å
349V94.2Very high80.4Confident0 Ų054.8 Ų54.80%030%0.298CS..EExtended strand (participates in β ladder)trans-117.3122.1-178-178.90000109.4T282 F283 L293 V296 A311 I312 I351 F367T282-V349 CarbonylContact C-O 3.55Å; T282-V349 WeakPolarHBondContact CA-O 3.43Å; F283-V349 HydrophobicContact CB-CB 4.39Å; F283-V349 PolarHBondContact N-O 2.99Å; F283-V349 PolarHBondContact O-N 3.35Å; L293-V349 HydrophobicContact CD2-CG2 4.42Å; V296-V349 HydrophobicContact CG1-CG1 4.03Å; V296-V349 HydrophobicContact CG2-CG2 4.35Å; A311-V349 CarbonylContact O-C 3.44Å; A311-V349 WeakPolarHBondContact O-CA 3.47Å; I312-V349 HydrophobicContact CG1-CG1 4.1Å; I312-V349 HydrophobicContact CG1-CG2 4.26Å; V349-I351 HydrophobicContact CG1-CD1 3.92Å; V349-I351 HydrophobicContact CG1-CG1 4.42Å; V349-F367 HydrophobicContact CB-CE1 3.98Å; V349-F367 HydrophobicContact CG1-CE1 4.03Å; V349-F367 HydrophobicContact CG2-CD1 4.36Å; V349-F367 HydrophobicContact CG2-CE1 3.87Å
350G93.8Very high81.2Confident5 Ų546.7 Ų46.75%0.05226%0.261CS..EExtended strand (participates in β ladder)trans-98.3124.4175.800000111.2W281 I310 A311W281-G350 CarbonylContact O-C 3.46Å; W281-G350 VanDerWaalsContact O-CA 3.31Å; W281-G350 WeakPolarHBondContact O-CA 3.48Å; I310-G350 VanDerWaalsContact CG1-O 3.28Å; I310-G350 WeakPolarHBondContact CG1-O 3.23Å; I310-G350 PolarHBondContact N-O 3.49Å; A311-G350 PolarHBondContact N-O 3.36Å; A311-G350 PolarHBondContact O-N 3.25Å
351I94.6Very high82.3Confident0 Ų041.9 Ų41.90%023%0.234CC..EExtended strand (participates in β ladder)trans-116.6123.9175.1-54.1-59.7000108.3T280 W281 F283 L298 F307 S308 I309 V349 I365T280-I351 CarbonylContact C-O 3.59Å; T280-I351 VanDerWaalsContact CA-O 3.29Å; T280-I351 WeakPolarHBondContact CA-O 3.37Å; W281-I351 PolarHBondContact N-O 3.35Å; W281-I351 PolarHBondContact O-N 3.08Å; F283-I351 HydrophobicContact CD2-CG1 4.12Å; F283-I351 HydrophobicContact CE2-CG1 3.96Å; L298-I351 HydrophobicContact CD2-CD1 4.32Å; L298-I351 HydrophobicContact CD2-CG2 4.43Å; F307-I351 HydrophobicContact CD1-CG2 4.47Å; S308-I351 CarbonylContact O-C 3.19Å; S308-I351 WeakPolarHBondContact O-CA 3.25Å; I309-I351 HydrophobicContact CB-CD1 4.27Å; I309-I351 HydrophobicContact CG1-CD1 3.75Å; I309-I351 HydrophobicContact CG2-CD1 4.34Å; V349-I351 HydrophobicContact CG1-CD1 3.92Å; V349-I351 HydrophobicContact CG1-CG1 4.42Å; I351-I365 HydrophobicContact CD1-CG2 4.34Å; I351-I365 HydrophobicContact CG1-CD1 3.89Å; I351-I365 HydrophobicContact CG1-CG1 4.26Å; I351-I365 HydrophobicContact CG2-CD1 4.43Å
352A93.4Very high83.3Confident5 Ų541.2 Ų41.24%0.04121%0.205CC..EExtended strand (participates in β ladder)trans-98.7146174.400000111.4Q279 F307 S308 I310Q279-A352 CarbonylContact O-C 3.53Å; Q279-A352 WeakPolarHBondContact O-CA 3.31Å; F307-A352 CarbonylContact C-O 3.51Å; F307-A352 VanDerWaalsContact CA-O 3.31Å; F307-A352 WeakPolarHBondContact CA-O 3.26Å; S308-A352 PolarHBondContact N-O 2.92Å; S308-A352 PolarHBondContact O-N 3.17Å; I310-A352 HydrophobicContact CB-CB 4.45Å; I310-A352 HydrophobicContact CD1-CB 4.16Å; I310-A352 HydrophobicContact CG1-CB 4.24Å; I310-A352 HydrophobicContact CG2-CB 3.42Å; I310-A352 VanDerWaalsContact CG2-CB 3.42Å
353F92.1Very high84.2Confident1 Ų138.7 Ų38.70%0.00419%0.191CC..EExtended strand (participates in β ladder)trans-122.6137.9166.7170.9-94.9000110.5H278 Q279 W281 H306 F307 T355 F361 I381H278-F353 VanDerWaalsContact CA-O 3.3Å; H278-F353 WeakPolarHBondContact CA-O 3.34Å; H278-F353 PolarHBondContact ND1-O 3.25Å; Q279-F353 HydrophobicContact CB-CB 4.5Å; Q279-F353 HydrophobicContact CB-CD1 4.48Å; Q279-F353 PolarHBondContact N-O 2.87Å; Q279-F353 PolarHBondContact O-N 2.75Å; W281-F353 HydrophobicContact CH2-CB 4.12Å; W281-F353 HydrophobicContact CZ3-CB 3.57Å; W281-F353 HydrophobicContact CZ3-CG 4.49Å; H306-F353 HydrophobicContact CB-CD2 3.84Å; H306-F353 HydrophobicContact CB-CE2 3.6Å; H306-F353 CarbonylContact O-C 3.23Å; H306-F353 WeakPolarHBondContact O-CA 3.34Å; F307-F353 HydrophobicContact CD1-CB 4.06Å; F307-F353 AromaticContact CD1-CD2 3.94Å; F307-F353 HydrophobicContact CD1-CD2 3.94Å; F307-F353 HydrophobicContact CD1-CG 4.49Å; F307-F353 HydrophobicContact CD2-CD2 4.1Å; F307-F353 HydrophobicContact CE1-CB 3.96Å; F307-F353 AromaticContact CE1-CD2 3.54Å; F307-F353 HydrophobicContact CE1-CD2 3.54Å; F307-F353 HydrophobicContact CE1-CE2 4.44Å; F307-F353 HydrophobicContact CE1-CG 4.12Å; F307-F353 AromaticContact CE2-CD2 3.73Å; F307-F353 HydrophobicContact CE2-CD2 3.73Å; F307-F353 AromaticContact CE2-CE2 3.97Å; F307-F353 HydrophobicContact CE2-CE2 3.97Å; F307-F353 HydrophobicContact CG-CD2 4.21Å; F307-F353 AromaticContact CZ-CD2 3.43Å; F307-F353 HydrophobicContact CZ-CD2 3.43Å; F307-F353 VanDerWaalsContact CZ-CD2 3.43Å; F307-F353 AromaticContact CZ-CE2 3.88Å; F307-F353 HydrophobicContact CZ-CE2 3.88Å; F307-F353 HydrophobicContact CZ-CG 4.36Å; F353-T355 HydrophobicContact CE1-CG2 3.47Å; F353-T355 VanDerWaalsContact CE1-CG2 3.47Å; F353-T355 HydrophobicContact CZ-CG2 3.55Å; F353-F361 HydrophobicContact CE2-CB 3.63Å; F353-F361 AromaticContact CE2-CD1 3.94Å; F353-F361 HydrophobicContact CE2-CD1 3.94Å; F353-F361 AromaticContact CE2-CD2 3.78Å; F353-F361 HydrophobicContact CE2-CD2 3.78Å; F353-F361 HydrophobicContact CE2-CE2 4.4Å; F353-F361 AromaticContact CE2-CG 3.51Å; F353-F361 HydrophobicContact CE2-CG 3.51Å; F353-F361 HydrophobicContact CZ-CB 4.09Å; F353-F361 HydrophobicContact CZ-CD1 4.26Å; F353-F361 AromaticContact CZ-CD2 3.39Å; F353-F361 HydrophobicContact CZ-CD2 3.39Å; F353-F361 AromaticContact CZ-CE2 3.77Å; F353-F361 HydrophobicContact CZ-CE2 3.77Å; F353-F361 AromaticContact CZ-CG 3.66Å; F353-F361 HydrophobicContact CZ-CG 3.66Å; F353-F361 HydrophobicContact CZ-CZ 4.34Å; F353-I381 HydrophobicContact CD1-CD1 3.59Å; F353-I381 HydrophobicContact CD1-CG1 4.32Å; F353-I381 HydrophobicContact CD1-CG2 3.82Å; F353-I381 HydrophobicContact CD2-CG2 3.81Å; F353-I381 HydrophobicContact CE1-CB 4.46Å; F353-I381 HydrophobicContact CE1-CD1 3.75Å; F353-I381 HydrophobicContact CE1-CG1 4.07Å; F353-I381 HydrophobicContact CE1-CG2 3.59Å; F353-I381 HydrophobicContact CE2-CG2 3.59Å; F353-I381 HydrophobicContact CG-CD1 4.41Å; F353-I381 HydrophobicContact CG-CG2 3.9Å; F353-I381 HydrophobicContact CZ-CG2 3.47Å; F353-I381 VanDerWaalsContact CZ-CG2 3.47Å
354N89.7Confident84.8Confident89 Ų8932.1 Ų32.148%0.47616%0.156SC..EExtended strand (participates in β ladder)trans-140.7130175.5-171.322.9000110.7S277 H306S277-N354 WeakPolarHBondContact O-CA 3.32Å; S277-N354 PolarHBondContact O-OD1 2.91Å; H306-N354 WeakPolarHBondContact CA-O 3.5Å; H306-N354 WeakPolarHBondContact CB-O 3.46Å; H306-N354 PolarHBondContact ND1-O 3.19Å; H306-N354 PolarHBondContact O-N 2.91Å
355T84Confident85.3Confident2 Ų230.1 Ų30.11%0.01215%0.147CC..EExtended strand (participates in β ladder)trans-140.2153.3173.5-174.40000111.1K275 K276 S277 F353 I357 F361 A383K275-T355 CarbonylContact O-C 3.47Å; K276-T355 WeakPolarHBondContact CA-O 3.16Å; S277-T355 PolarHBondContact N-O 3.11Å; S277-T355 PolarHBondContact O-N 3.32Å; S277-T355 VanDerWaalsContact O-N 3.16Å; S277-T355 VanDerWaalsContact OG-CG2 3.22Å; S277-T355 WeakPolarHBondContact OG-CG2 3.48Å; F353-T355 HydrophobicContact CE1-CG2 3.47Å; F353-T355 VanDerWaalsContact CE1-CG2 3.47Å; F353-T355 HydrophobicContact CZ-CG2 3.55Å; T355-I357 WeakPolarHBondContact CG2-O 3.27Å; T355-I357 WeakPolarHBondContact OG1-CG1 3.24Å; T355-I357 PolarHBondContact OG1-N 3.08Å; T355-I357 PolarHBondContact OG1-O 2.68Å; T355-F361 HydrophobicContact CG2-CE2 4.22Å; T355-F361 WeakPolarHBondContact OG1-CZ 3.13Å; T355-A383 HydrophobicContact CG2-CB 4.18Å
356E82.2Confident85.7Confident123 Ų12329 Ų2958%0.57514%0.143SC*.SBendtrans-113.21.4168.4-58.5-159.8137.700112.5K275 K276K275-E356 CarbonylContact O-C 3.53Å; K275-E356 VanDerWaalsContact O-C 3.23Å; K275-E356 WeakPolarHBondContact O-CA 3.44Å; K276-E356 WeakPolarHBondContact CE-OE1 3.3Å; K276-E356 HydrophobicContact CG-CG 4.44Å; K276-E356 IonicContact NZ-OE1 3.59Å; K276-E356 PolarHBondContact NZ-OE1 3.15Å; K276-E356 VanDerWaalsContact NZ-OE1 3.08Å
357I74.8Confident86Confident96 Ų9628.4 Ų28.449%0.49214%0.139SC..SBendtrans-120150.7-178.967.6176.2000110.5T355 F361T355-I357 WeakPolarHBondContact CG2-O 3.27Å; T355-I357 WeakPolarHBondContact OG1-CG1 3.24Å; T355-I357 PolarHBondContact OG1-N 3.08Å; T355-I357 PolarHBondContact OG1-O 2.68Å; I357-F361 HydrophobicContact CD1-CZ 4.17Å; I357-F361 HydrophobicContact CG1-CZ 3.82Å
358F74.7Confident86.1Confident64 Ų6429.3 Ų29.328%0.28114%0.144SC..  trans-72.7148.7164.4-64.8-47.8000110K275 A383 A384 Q444K275-F358 HydrophobicContact CB-CE1 4.3Å; K275-F358 HydrophobicContact CB-CZ 4.39Å; K275-F358 HydrophobicContact CD-CD2 4.36Å; K275-F358 HydrophobicContact CD-CE2 3.97Å; K275-F358 HydrophobicContact CD-CZ 4.22Å; K275-F358 HydrophobicContact CG-CD1 3.97Å; K275-F358 HydrophobicContact CG-CD2 3.89Å; K275-F358 HydrophobicContact CG-CE1 3.54Å; K275-F358 HydrophobicContact CG-CE2 3.45Å; K275-F358 VanDerWaalsContact CG-CE2 3.45Å; K275-F358 HydrophobicContact CG-CG 4.14Å; K275-F358 HydrophobicContact CG-CZ 3.26Å; F358-A383 CarbonylContact C-O 3.55Å; F358-A383 WeakPolarHBondContact CA-O 3.4Å; F358-A383 VanDerWaalsContact CB-O 3.25Å; F358-A383 WeakPolarHBondContact CB-O 3.35Å; F358-A383 HydrophobicContact CD1-CB 4.35Å; F358-A383 WeakPolarHBondContact CD1-O 3.4Å; F358-A384 VanDerWaalsContact CE1-C 3.42Å; F358-A384 VanDerWaalsContact CE1-O 3.23Å; F358-A384 WeakPolarHBondContact CE1-O 3.49Å; F358-Q444 HydrophobicContact CB-CG 4.42Å
359G68.2Low85.9Confident13 Ų1325.3 Ų25.313%0.13413%0.127CC..EExtended strand (participates in β ladder)trans154175-177.300000111.6F361 A383G359-F361 WeakPolarHBondContact O-CE2 3.28Å; G359-A383 PolarHBondContact N-O 2.92Å; G359-A383 PolarHBondContact O-N 3.3Å
360T72.2Confident85.5Confident12 Ų1227.6 Ų27.67%0.07415%0.151CC..EExtended strand (participates in β ladder)trans-110.4129.8176.3-62.90000109.3M380 I381 D382 T443 Q444T360-M380 HydrophobicContact CG2-CG 4.21Å; T360-I381 WeakPolarHBondContact CA-O 3.33Å; T360-D382 WeakPolarHBondContact CB-OD1 3.29Å; T360-D382 WeakPolarHBondContact CG2-OD1 3.37Å; T360-D382 PolarHBondContact OG1-OD1 2.94Å; T360-T443 HydrophobicContact CG2-CG2 3.69Å; T360-T443 VanDerWaalsContact OG1-CB 3.22Å; T360-T443 WeakPolarHBondContact OG1-CB 3.33Å; T360-Q444 PolarHBondContact OG1-N 3.49Å
361F77.4Confident85Confident7 Ų732.1 Ų32.13%0.03117%0.173CC..EExtended strand (participates in β ladder)trans-123.8124.2-174.7-55.4-94.9000109.1H303 H306 F307 F353 T355 I357 G359 M380 I381 A383H303-F361 HydrophobicContact CB-CD1 4.25Å; H303-F361 AromaticContact CE1-CD1 3.96Å; H303-F361 AromaticContact CG-CD1 3.83Å; H303-F361 AromaticContact ND1-CD1 3.53Å; H306-F361 AromaticContact CD2-CD1 3.82Å; H306-F361 AromaticContact CD2-CE1 3.47Å; H306-F361 VanDerWaalsContact CD2-CE1 3.47Å; H306-F361 WeakPolarHBondContact CD2-CE1 3.4Å; H306-F361 AromaticContact CG-CE1 3.94Å; H306-F361 AromaticContact NE2-CE1 3.59Å; F307-F361 HydrophobicContact CE2-CB 3.87Å; F307-F361 HydrophobicContact CZ-CB 3.94Å; F353-F361 HydrophobicContact CE2-CB 3.63Å; F353-F361 AromaticContact CE2-CD1 3.94Å; F353-F361 HydrophobicContact CE2-CD1 3.94Å; F353-F361 AromaticContact CE2-CD2 3.78Å; F353-F361 HydrophobicContact CE2-CD2 3.78Å; F353-F361 HydrophobicContact CE2-CE2 4.4Å; F353-F361 AromaticContact CE2-CG 3.51Å; F353-F361 HydrophobicContact CE2-CG 3.51Å; F353-F361 HydrophobicContact CZ-CB 4.09Å; F353-F361 HydrophobicContact CZ-CD1 4.26Å; F353-F361 AromaticContact CZ-CD2 3.39Å; F353-F361 HydrophobicContact CZ-CD2 3.39Å; F353-F361 AromaticContact CZ-CE2 3.77Å; F353-F361 HydrophobicContact CZ-CE2 3.77Å; F353-F361 AromaticContact CZ-CG 3.66Å; F353-F361 HydrophobicContact CZ-CG 3.66Å; F353-F361 HydrophobicContact CZ-CZ 4.34Å; T355-F361 HydrophobicContact CG2-CE2 4.22Å; T355-F361 WeakPolarHBondContact OG1-CZ 3.13Å; I357-F361 HydrophobicContact CD1-CZ 4.17Å; I357-F361 HydrophobicContact CG1-CZ 3.82Å; G359-F361 WeakPolarHBondContact O-CE2 3.28Å; F361-M380 WeakPolarHBondContact O-CA 3.45Å; F361-I381 HydrophobicContact CB-CG2 3.79Å; F361-I381 HydrophobicContact CD2-CG2 4.28Å; F361-I381 HydrophobicContact CG-CG2 4.45Å; F361-I381 PolarHBondContact N-O 3.45Å; F361-I381 PolarHBondContact O-N 3.11Å; F361-A383 HydrophobicContact CE2-CB 4.42Å
362R79.6Confident84.5Confident75 Ų7537.1 Ų37.128%0.28320%0.196SC..EExtended strand (participates in β ladder)trans-116.4136.4178.7-66.4179.6173.8155.72.4109.7H303 M380 Q440 D462H303-R362 PolarHBondContact CD2-O 3.46Å; R362-M380 HydrophobicContact CG-CB 4.24Å; R362-M380 HydrophobicContact CG-CG 3.88Å; R362-Q440 PolarHBondContact NH2-O 3.31Å; R362-D462 IonicContact CZ-OD1 2.68Å; R362-D462 VanDerWaalsContact CZ-OD1 3.27Å; R362-D462 IonicContact NH1-OD1 2.57Å; R362-D462 PolarHBondContact NH1-OD1 3Å; R362-D462 IonicContact NH2-OD1 2.72Å; R362-D462 PolarHBondContact NH2-OD1 3.34Å
363Q84.9Confident84.3Confident1 Ų138.9 Ų38.91%0.00521%0.207CC..EExtended strand (participates in β ladder)trans-142.5142.9175.3-174.958.6-7600110.8L298 Y300 F307 V379L298-Q363 HydrophobicContact CB-CG 4.28Å; L298-Q363 HydrophobicContact CD2-CG 3.96Å; Y300-Q363 VanDerWaalsContact N-OE1 3.11Å; Y300-Q363 PolarHBondContact O-NE2 2.99Å; Y300-Q363 PolarHBondContact O-OE1 3.41Å; F307-Q363 HydrophobicContact CB-CG 4.43Å; F307-Q363 HydrophobicContact CD1-CB 4.06Å; F307-Q363 HydrophobicContact CD1-CG 4.33Å; F307-Q363 HydrophobicContact CD2-CB 3.94Å; F307-Q363 HydrophobicContact CD2-CG 4.26Å; F307-Q363 HydrophobicContact CE1-CB 3.94Å; F307-Q363 HydrophobicContact CE2-CB 3.81Å; F307-Q363 HydrophobicContact CG-CB 4.05Å; F307-Q363 HydrophobicContact CG-CG 4.1Å; F307-Q363 HydrophobicContact CZ-CB 3.82Å; Q363-V379 HydrophobicContact CB-CG2 3.92Å; Q363-V379 PolarHBondContact N-O 2.85Å; Q363-V379 WeakPolarHBondContact O-CG2 3.35Å; Q363-V379 PolarHBondContact O-N 2.97Å
364T86.6Confident84.2Confident7 Ų739 Ų394%0.04321%0.208CC..EExtended strand (participates in β ladder)trans-107.1119.3173.7-59.80000108.6L299 Y300 V366 M376 R378L299-T364 HydrophobicContact CB-CG2 4.28Å; L299-T364 WeakPolarHBondContact CB-O 3.22Å; L299-T364 HydrophobicContact CD2-CG2 3.98Å; L299-T364 PolarHBondContact N-O 2.73Å; Y300-T364 WeakPolarHBondContact CE2-OG1 3.49Å; T364-V366 HydrophobicContact CG2-CG2 4.22Å; T364-M376 HydrophobicContact CG2-CB 3.97Å; T364-M376 HydrophobicContact CG2-SD 4.3Å; T364-R378 HydrophobicContact CG2-CG 4.39Å
365I92.6Very high84.3Confident0 Ų034.8 Ų34.80%019%0.186CC..EExtended strand (participates in β ladder)trans-95.2131.1176.2-55.5146.8000107.6F283 V296 L298 I351 F367 M376 Q377 V379F283-I365 HydrophobicContact CD2-CD1 4.37Å; F283-I365 HydrophobicContact CE1-CD1 4.45Å; F283-I365 HydrophobicContact CE2-CD1 3.4Å; F283-I365 HydrophobicContact CZ-CD1 3.45Å; F283-I365 VanDerWaalsContact CZ-CD1 3.45Å; V296-I365 HydrophobicContact CG1-CG2 4.24Å; L298-I365 HydrophobicContact CD2-CB 4.42Å; L298-I365 HydrophobicContact CD2-CG1 3.69Å; L298-I365 HydrophobicContact CD2-CG2 4.47Å; I351-I365 HydrophobicContact CD1-CG2 4.34Å; I351-I365 HydrophobicContact CG1-CD1 3.89Å; I351-I365 HydrophobicContact CG1-CG1 4.26Å; I351-I365 HydrophobicContact CG2-CD1 4.43Å; I365-F367 HydrophobicContact CB-CE2 4.32Å; I365-F367 HydrophobicContact CB-CZ 4.34Å; I365-F367 HydrophobicContact CG2-CD2 4.49Å; I365-F367 HydrophobicContact CG2-CE1 3.89Å; I365-F367 HydrophobicContact CG2-CE2 3.77Å; I365-F367 HydrophobicContact CG2-CZ 3.43Å; I365-F367 VanDerWaalsContact CG2-CZ 3.43Å; I365-M376 CarbonylContact O-C 3.55Å; I365-M376 VanDerWaalsContact O-CA 3.29Å; I365-M376 WeakPolarHBondContact O-CA 3.43Å; I365-Q377 PolarHBondContact N-O 2.97Å; I365-Q377 PolarHBondContact O-N 3.19Å; I365-V379 HydrophobicContact CD1-CB 4.47Å; I365-V379 HydrophobicContact CD1-CG1 3.72Å; I365-V379 HydrophobicContact CD1-CG2 3.9Å; I365-V379 HydrophobicContact CG1-CG2 4.48Å
366V93.4Very high84.7Confident1 Ų135.3 Ų35.31%0.00619%0.188CC..EExtended strand (participates in β ladder)trans-117.2132.5-176.1178.90000109.3L239 L253 V296 A297 L299 T364 V374 L375L239-V366 HydrophobicContact CD2-CG1 3.75Å; L253-V366 HydrophobicContact CD2-CG1 4.39Å; L253-V366 HydrophobicContact CD2-CG2 4.48Å; V296-V366 CarbonylContact C-O 3.55Å; V296-V366 VanDerWaalsContact CA-O 3.28Å; V296-V366 WeakPolarHBondContact CA-O 3.41Å; A297-V366 PolarHBondContact N-O 2.97Å; A297-V366 PolarHBondContact O-N 2.85Å; L299-V366 HydrophobicContact CB-CG2 4.04Å; L299-V366 HydrophobicContact CD1-CG2 4.14Å; L299-V366 HydrophobicContact CD2-CG2 4.27Å; L299-V366 HydrophobicContact CG-CG2 4.39Å; T364-V366 HydrophobicContact CG2-CG2 4.22Å; V366-V374 HydrophobicContact CG1-CB 4.27Å; V366-V374 HydrophobicContact CG1-CG1 3.2Å; V366-L375 CarbonylContact C-O 3.51Å; V366-L375 WeakPolarHBondContact CA-O 3.32Å
367F93.9Very high84.9Confident0 Ų030.6 Ų30.60%017%0.166CC..EExtended strand (participates in β ladder)trans-119.6108.8179.1-52.9-83.3000109.4F283 L285 L293 V296 V349 I365 F369 V374 L375 Q377F283-F367 HydrophobicContact CB-CZ 4.02Å; F283-F367 HydrophobicContact CD1-CZ 4.23Å; F283-F367 HydrophobicContact CD2-CZ 4.28Å; F283-F367 AromaticContact CG-CZ 3.91Å; F283-F367 HydrophobicContact CG-CZ 3.91Å; L285-F367 HydrophobicContact CD1-CB 4.21Å; L285-F367 HydrophobicContact CD1-CD1 3.54Å; L285-F367 HydrophobicContact CD1-CE1 3.96Å; L285-F367 HydrophobicContact CD1-CG 3.85Å; L293-F367 HydrophobicContact CD1-CB 3.88Å; V296-F367 HydrophobicContact CG1-CD1 4.08Å; V296-F367 HydrophobicContact CG1-CE1 4.06Å; V296-F367 HydrophobicContact CG2-CD1 3.96Å; V296-F367 HydrophobicContact CG2-CE1 4.49Å; V349-F367 HydrophobicContact CB-CE1 3.98Å; V349-F367 HydrophobicContact CG1-CE1 4.03Å; V349-F367 HydrophobicContact CG2-CD1 4.36Å; V349-F367 HydrophobicContact CG2-CE1 3.87Å; I365-F367 HydrophobicContact CB-CE2 4.32Å; I365-F367 HydrophobicContact CB-CZ 4.34Å; I365-F367 HydrophobicContact CG2-CD2 4.49Å; I365-F367 HydrophobicContact CG2-CE1 3.89Å; I365-F367 HydrophobicContact CG2-CE2 3.77Å; I365-F367 HydrophobicContact CG2-CZ 3.43Å; I365-F367 VanDerWaalsContact CG2-CZ 3.43Å; F367-F369 HydrophobicContact CB-CE2 4.12Å; F367-V374 WeakPolarHBondContact O-CG1 3.15Å; F367-L375 HydrophobicContact CB-CB 4.2Å; F367-L375 HydrophobicContact CB-CD2 4.17Å; F367-L375 HydrophobicContact CB-CG 4.43Å; F367-L375 HydrophobicContact CD2-CD2 4Å; F367-L375 HydrophobicContact CD2-CG 4.09Å; F367-L375 HydrophobicContact CG-CD2 4.39Å; F367-L375 PolarHBondContact N-O 2.9Å; F367-L375 PolarHBondContact O-N 3.31Å; F367-Q377 HydrophobicContact CE2-CB 4.11Å; F367-Q377 HydrophobicContact CE2-CG 3.82Å
368D92.8Very high85.3Confident20 Ų2030 Ų3011%0.10716%0.157CC..EExtended strand (participates in β ladder)trans-100.2116.6-175.9-173.47.1000111.9Y235 Y294 R295 G370 V374Y235-D368 WeakPolarHBondContact OH-CB 3.2Å; Y235-D368 PolarHBondContact OH-OD2 3.34Å; Y294-D368 PolarHBondContact N-O 3.47Å; R295-D368 HydrophobicContact CB-CB 3.92Å; R295-D368 PolarHBondContact N-O 3.47Å; R295-D368 VanDerWaalsContact N-O 3.17Å; R295-D368 PolarHBondContact O-N 3.24Å; D368-G370 WeakPolarHBondContact OD1-CA 3.27Å; D368-G370 PolarHBondContact OD1-N 2.73Å; D368-V374 HydrophobicContact CB-CG1 3.97Å
369F89.4Confident85.6Confident10 Ų1027 Ų274%0.04415%0.145CC..  trans-98.411.7176.1-62.3-84.3000112.8I257 V260 L285 C287 R291 M292 L293 Y294 Y347 F367 L371 L375I257-F369 HydrophobicContact CD1-CD2 3.6Å; I257-F369 HydrophobicContact CD1-CE2 3.81Å; V260-F369 HydrophobicContact CG1-CE2 4.34Å; V260-F369 HydrophobicContact CG1-CZ 4.11Å; V260-F369 HydrophobicContact CG2-CE2 4.25Å; V260-F369 HydrophobicContact CG2-CZ 4.28Å; L285-F369 HydrophobicContact CD1-CZ 4.05Å; C287-F369 WeakPolarHBondContact SG-CE1 3.44Å; R291-F369 HydrophobicContact CB-CD1 4.02Å; M292-F369 WeakPolarHBondContact O-CA 3.43Å; L293-F369 HydrophobicContact CB-CD1 4.24Å; L293-F369 HydrophobicContact CB-CE1 4.01Å; L293-F369 HydrophobicContact CD1-CD1 4.11Å; L293-F369 HydrophobicContact CD1-CD2 4.48Å; L293-F369 HydrophobicContact CD1-CE1 3.8Å; L293-F369 HydrophobicContact CD1-CE2 4.21Å; L293-F369 HydrophobicContact CD1-CG 4.45Å; L293-F369 HydrophobicContact CD1-CZ 3.87Å; L293-F369 HydrophobicContact CG-CE1 4.48Å; Y294-F369 VanDerWaalsContact CD2-C 3.42Å; Y294-F369 WeakPolarHBondContact CD2-O 3.47Å; Y294-F369 WeakPolarHBondContact CE2-O 3.21Å; Y347-F369 HydrophobicContact CD2-CE1 4.31Å; Y347-F369 HydrophobicContact CE2-CE1 4.2Å; F367-F369 HydrophobicContact CB-CE2 4.12Å; F369-L371 VanDerWaalsContact C-N 3.27Å; F369-L375 HydrophobicContact CE2-CB 4.28Å; F369-L375 HydrophobicContact CE2-CD2 4.04Å
370G84.2Confident86.1Confident49 Ų4927.1 Ų27.151%0.50514%0.142SC..SBendtrans75.915.6-176.400000113.3D368D368-G370 WeakPolarHBondContact OD1-CA 3.27Å; D368-G370 PolarHBondContact OD1-N 2.73Å
371L83.8Confident86.5Confident99 Ų9926.5 Ų26.552%0.51814%0.138SC..SBendtrans-132.6147.8-178.9-64.6174.5000109.5F369 P373F369-L371 VanDerWaalsContact C-N 3.27Å; L371-P373 CarbonylContact O-C 3.57Å
372E85.5Confident86.2Confident106 Ų10626.2 Ų26.250%0.49514%0.137SC..SBendtrans-100.9139.9171.9-61-165142.900110.5K242K242-E372 WeakPolarHBondContact CE-OE1 3.36Å; K242-E372 WeakPolarHBondContact CE-OE2 3.38Å; K242-E372 IonicContact NZ-OE1 3.9Å; K242-E372 PolarHBondContact NZ-OE1 3.2Å; K242-E372 IonicContact NZ-OE2 2.9Å; K242-E372 PolarHBondContact NZ-OE2 2.82Å
373P87.9Confident86.2Confident41 Ų4122.6 Ų22.627%0.26612%0.123SC..SBendcis-73.5147.90.928.7-33.8000113.5E250 K251 I257 L371E250-P373 WeakPolarHBondContact O-CB 3.27Å; K251-P373 VanDerWaalsContact O-CA 3.3Å; K251-P373 WeakPolarHBondContact O-CA 2.99Å; K251-P373 WeakPolarHBondContact O-CB 3.36Å; I257-P373 HydrophobicContact CG2-CG 4.09Å; I257-P373 WeakPolarHBondContact CG2-O 3.42Å; L371-P373 CarbonylContact O-C 3.57Å
374V91.2Very high85.6Confident5 Ų522.6 Ų22.63%0.0312%0.123CC..EExtended strand (participates in β ladder)trans-75.2135.7173.2-173.60000109L239 V252 L253 S254 V366 F367 D368L239-V374 HydrophobicContact CD1-CG2 4.17Å; V252-V374 PolarHBondContact O-N 3.22Å; L253-V374 WeakPolarHBondContact CA-O 3.13Å; L253-V374 HydrophobicContact CD2-CB 4.02Å; S254-V374 PolarHBondContact N-O 2.97Å; V366-V374 HydrophobicContact CG1-CB 4.27Å; V366-V374 HydrophobicContact CG1-CG1 3.2Å; F367-V374 WeakPolarHBondContact O-CG1 3.15Å; D368-V374 HydrophobicContact CB-CG1 3.97Å
375L91.8Very high85.1Confident0 Ų023.3 Ų23.30%013%0.129CC..EExtended strand (participates in β ladder)trans-72.8130.7-178.617568.5000110S254 E255 I257 V260 V262 L285 V366 F367 F369S254-L375 CarbonylContact O-C 3.53Å; S254-L375 WeakPolarHBondContact O-CA 3.36Å; E255-L375 WeakPolarHBondContact O-CD1 3.42Å; I257-L375 HydrophobicContact CD1-CB 3.91Å; I257-L375 HydrophobicContact CG1-CB 4.25Å; I257-L375 HydrophobicContact CG1-CD1 4.36Å; I257-L375 HydrophobicContact CG2-CB 4.17Å; I257-L375 HydrophobicContact CG2-CD1 4.37Å; V260-L375 HydrophobicContact CG1-CD2 4.15Å; V262-L375 HydrophobicContact CG2-CD1 4.22Å; V262-L375 HydrophobicContact CG2-CD2 3.69Å; L285-L375 HydrophobicContact CD2-CD2 4.06Å; V366-L375 CarbonylContact C-O 3.51Å; V366-L375 WeakPolarHBondContact CA-O 3.32Å; F367-L375 HydrophobicContact CB-CB 4.2Å; F367-L375 HydrophobicContact CB-CD2 4.17Å; F367-L375 HydrophobicContact CB-CG 4.43Å; F367-L375 HydrophobicContact CD2-CD2 4Å; F367-L375 HydrophobicContact CD2-CG 4.09Å; F367-L375 HydrophobicContact CG-CD2 4.39Å; F367-L375 PolarHBondContact N-O 2.9Å; F367-L375 PolarHBondContact O-N 3.31Å; F369-L375 HydrophobicContact CE2-CB 4.28Å; F369-L375 HydrophobicContact CE2-CD2 4.04Å
376M90.8Very high84.1Confident13 Ų1327.6 Ų27.66%0.06416%0.155CC..EExtended strand (participates in β ladder)trans-122.2148.3174.369169.6-175.300112.3L253 S254 E255 T364 I365L253-M376 HydrophobicContact CB-CG 4.44Å; L253-M376 HydrophobicContact CB-SD 3.92Å; L253-M376 HydrophobicContact CD1-SD 4.38Å; S254-M376 PolarHBondContact O-N 3.44Å; E255-M376 WeakPolarHBondContact CA-O 3.36Å; E255-M376 HydrophobicContact CG-CE 3.58Å; E255-M376 HydrophobicContact CG-CG 4.26Å; T364-M376 HydrophobicContact CG2-CB 3.97Å; T364-M376 HydrophobicContact CG2-SD 4.3Å; I365-M376 CarbonylContact O-C 3.55Å; I365-M376 VanDerWaalsContact O-CA 3.29Å; I365-M376 WeakPolarHBondContact O-CA 3.43Å
377Q86.6Confident83Confident23 Ų2334.3 Ų34.311%0.10719%0.186CC..EExtended strand (participates in β ladder)trans-133.5134170.3-68-64.1-53.700109.2E255 V262 F283 I365 F367E255-Q377 PolarHBondContact O-NE2 2.81Å; E255-Q377 VanDerWaalsContact O-NE2 3.13Å; V262-Q377 HydrophobicContact CG1-CG 4.18Å; F283-Q377 HydrophobicContact CD1-CB 4.43Å; F283-Q377 HydrophobicContact CD1-CG 4.24Å; F283-Q377 HydrophobicContact CE1-CB 3.8Å; F283-Q377 HydrophobicContact CE1-CG 4.04Å; F283-Q377 HydrophobicContact CZ-CB 4.43Å; I365-Q377 PolarHBondContact N-O 2.97Å; I365-Q377 PolarHBondContact O-N 3.19Å; F367-Q377 HydrophobicContact CE2-CB 4.11Å; F367-Q377 HydrophobicContact CE2-CG 3.82Å
378R82.8Confident81.7Confident83 Ų8336.6 Ų36.631%0.31320%0.198SC..EExtended strand (participates in β ladder)trans-104.7121.6-176.9-67.7173.5175.1175.5-3.7109.5E255 L268 T364E255-R378 IonicContact OE1-NH1 3.78Å; L268-R378 WeakPolarHBondContact CB-O 3.45Å; T364-R378 HydrophobicContact CG2-CG 4.39Å
379V81.1Confident80.3Confident3 Ų337.4 Ų37.42%0.01820%0.203CC..EExtended strand (participates in β ladder)trans-108.1146.5174-66.60000110.4L268 W281 F283 F307 Q363 I365L268-V379 HydrophobicContact CD2-CG1 3.83Å; L268-V379 CarbonylContact O-C 3.5Å; L268-V379 WeakPolarHBondContact O-CA 3.27Å; W281-V379 HydrophobicContact CD2-CG1 4.26Å; W281-V379 HydrophobicContact CG-CG1 4.35Å; W281-V379 HydrophobicContact CZ2-CB 4.43Å; F283-V379 HydrophobicContact CE2-CG1 4.43Å; F283-V379 HydrophobicContact CZ-CG1 3.69Å; F307-V379 HydrophobicContact CE1-CG2 4.07Å; Q363-V379 HydrophobicContact CB-CG2 3.92Å; Q363-V379 PolarHBondContact N-O 2.85Å; Q363-V379 WeakPolarHBondContact O-CG2 3.35Å; Q363-V379 PolarHBondContact O-N 2.97Å; I365-V379 HydrophobicContact CD1-CB 4.47Å; I365-V379 HydrophobicContact CD1-CG1 3.72Å; I365-V379 HydrophobicContact CD1-CG2 3.9Å; I365-V379 HydrophobicContact CG1-CG2 4.48Å
380M79.6Confident79.2Confident14 Ų1443.8 Ų43.87%0.06923%0.233CC..EExtended strand (participates in β ladder)trans-141.4136177.3178.3-94.4-74.100110L268 S269 V270 T360 F361 R362 Q440L268-M380 PolarHBondContact O-N 3.19Å; S269-M380 VanDerWaalsContact CA-O 3.31Å; S269-M380 WeakPolarHBondContact CA-O 3.49Å; S269-M380 WeakPolarHBondContact OG-CE 3.37Å; V270-M380 PolarHBondContact N-O 3.48Å; T360-M380 HydrophobicContact CG2-CG 4.21Å; F361-M380 WeakPolarHBondContact O-CA 3.45Å; R362-M380 HydrophobicContact CG-CB 4.24Å; R362-M380 HydrophobicContact CG-CG 3.88Å; M380-Q440 VanDerWaalsContact CE-CA 3.45Å; M380-Q440 HydrophobicContact CE-CB 3.93Å; M380-Q440 HydrophobicContact CE-CG 3.78Å
381I79.9Confident78.3Confident0 Ų049.5 Ų49.50%024%0.24CC..EExtended strand (participates in β ladder)trans-132.3129.8176.2-175.8154.6000111.2V270 V272 Q279 W281 F307 F353 T360 F361V270-I381 HydrophobicContact CB-CD1 4.41Å; V270-I381 HydrophobicContact CB-CG1 4.49Å; V270-I381 HydrophobicContact CG1-CD1 4.42Å; V270-I381 CarbonylContact O-C 3.54Å; V270-I381 VanDerWaalsContact O-CA 3.26Å; V270-I381 WeakPolarHBondContact O-CA 3.41Å; V272-I381 HydrophobicContact CG1-CD1 4.04Å; V272-I381 HydrophobicContact CG2-CD1 4.3Å; V272-I381 HydrophobicContact CG2-CG1 4.26Å; Q279-I381 HydrophobicContact CB-CD1 3.7Å; Q279-I381 HydrophobicContact CG-CD1 4.11Å; W281-I381 HydrophobicContact CH2-CB 3.99Å; W281-I381 HydrophobicContact CH2-CD1 4.05Å; W281-I381 HydrophobicContact CH2-CG2 4.21Å; W281-I381 HydrophobicContact CZ2-CB 4.36Å; F307-I381 HydrophobicContact CZ-CG2 4.2Å; F353-I381 HydrophobicContact CD1-CD1 3.59Å; F353-I381 HydrophobicContact CD1-CG1 4.32Å; F353-I381 HydrophobicContact CD1-CG2 3.82Å; F353-I381 HydrophobicContact CD2-CG2 3.81Å; F353-I381 HydrophobicContact CE1-CB 4.46Å; F353-I381 HydrophobicContact CE1-CD1 3.75Å; F353-I381 HydrophobicContact CE1-CG1 4.07Å; F353-I381 HydrophobicContact CE1-CG2 3.59Å; F353-I381 HydrophobicContact CE2-CG2 3.59Å; F353-I381 HydrophobicContact CG-CD1 4.41Å; F353-I381 HydrophobicContact CG-CG2 3.9Å; F353-I381 HydrophobicContact CZ-CG2 3.47Å; F353-I381 VanDerWaalsContact CZ-CG2 3.47Å; T360-I381 WeakPolarHBondContact CA-O 3.33Å; F361-I381 HydrophobicContact CB-CG2 3.79Å; F361-I381 HydrophobicContact CD2-CG2 4.28Å; F361-I381 HydrophobicContact CG-CG2 4.45Å; F361-I381 PolarHBondContact N-O 3.45Å; F361-I381 PolarHBondContact O-N 3.11Å
382D72.8Confident77.2Confident0 Ų044.9 Ų44.90%022%0.216CC..EExtended strand (participates in β ladder)trans-104.4111.9175.8-72.7-44.1000109.7V270 T271 V272 T360 T443V270-D382 PolarHBondContact O-N 2.98Å; T271-D382 CarbonylContact C-O 3.41Å; T271-D382 WeakPolarHBondContact CA-O 3.47Å; T271-D382 HydrophobicContact CG2-CB 4Å; V272-D382 PolarHBondContact N-O 2.96Å; T360-D382 WeakPolarHBondContact CB-OD1 3.29Å; T360-D382 WeakPolarHBondContact CG2-OD1 3.37Å; T360-D382 PolarHBondContact OG1-OD1 2.94Å; D382-T443 WeakPolarHBondContact OD1-CA 3.15Å; D382-T443 WeakPolarHBondContact OD1-CB 3.39Å; D382-T443 WeakPolarHBondContact OD1-CG2 3.25Å
383A78.9Confident76.1Confident0 Ų045.2 Ų45.20%022%0.219CC..EExtended strand (participates in β ladder)trans-98.2106.5170.100000109.4V272 T355 F358 G359 F361V272-A383 HydrophobicContact CG2-CB 3.74Å; V272-A383 WeakPolarHBondContact O-CA 3.23Å; T355-A383 HydrophobicContact CG2-CB 4.18Å; F358-A383 CarbonylContact C-O 3.55Å; F358-A383 WeakPolarHBondContact CA-O 3.4Å; F358-A383 VanDerWaalsContact CB-O 3.25Å; F358-A383 WeakPolarHBondContact CB-O 3.35Å; F358-A383 HydrophobicContact CD1-CB 4.35Å; F358-A383 WeakPolarHBondContact CD1-O 3.4Å; G359-A383 PolarHBondContact N-O 2.92Å; G359-A383 PolarHBondContact O-N 3.3Å; F361-A383 HydrophobicContact CE2-CB 4.42Å
384A71.4Confident74.8Confident0 Ų048.4 Ų48.40%023%0.23CC..  trans-127.3161.9-176.800000111.4V272 S273 F358 D388 L392V272-A384 PolarHBondContact O-N 2.72Å; S273-A384 CarbonylContact C-O 3.48Å; S273-A384 WeakPolarHBondContact CA-O 3.3Å; F358-A384 VanDerWaalsContact CE1-C 3.42Å; F358-A384 VanDerWaalsContact CE1-O 3.23Å; F358-A384 WeakPolarHBondContact CE1-O 3.49Å; A384-D388 HydrophobicContact CB-CB 4.28Å; A384-L392 HydrophobicContact CB-CD1 4.1Å
385S75.8Confident73.2Confident23 Ų2349.3 Ų49.316%0.16124%0.238CC..  trans-73.3163.2171.873.70000111.2E387 D388 L389S385-E387 VanDerWaalsContact C-N 3.3Å; S385-E387 PolarHBondContact O-N 3.47Å; S385-D388 PolarHBondContact O-N 3.49Å; S385-D388 VanDerWaalsContact OG-CB 3.29Å; S385-D388 WeakPolarHBondContact OG-CB 3.45Å; S385-D388 PolarHBondContact OG-N 3.01Å; S385-D388 VanDerWaalsContact OG-N 3.16Å; S385-D388 PolarHBondContact OG-OD2 2.97Å; S385-L389 VanDerWaalsContact O-CB 3.23Å; S385-L389 WeakPolarHBondContact O-CB 3.42Å; S385-L389 PolarHBondContact O-N 2.75Å
386T71.9Confident71.5Confident89 Ų8950.1 Ų50.155%0.54624%0.241SC..Hα-helixtrans-61.5-37.9177.144.40000112.7L389 E390T386-L389 PolarHBondContact O-N 3.46Å; T386-E390 PolarHBondContact O-N 3.44Å
387E70.1Confident69.8Low143 Ų14356.5 Ų56.567%0.66827%0.271SS*.Hα-helixtrans-67-48.2176.8-65.8170.6-170.100110.8S385 L389 E390 Y391S385-E387 VanDerWaalsContact C-N 3.3Å; S385-E387 PolarHBondContact O-N 3.47Å; E387-L389 VanDerWaalsContact C-N 3.28Å; E387-L389 PolarHBondContact O-N 3.35Å; E387-E390 PolarHBondContact O-N 3.12Å; E387-Y391 VanDerWaalsContact O-CD2 3.31Å; E387-Y391 WeakPolarHBondContact O-CD2 3.47Å; E387-Y391 PolarHBondContact O-N 3.12Å
388D66.5Low68.2Low47 Ų4761 Ų6125%0.25129%0.292SS..Hα-helixtrans-61-38.3176.4-70.9-31.8000111.5A384 S385 E390 Y391 L392 Q444 L447A384-D388 HydrophobicContact CB-CB 4.28Å; S385-D388 PolarHBondContact O-N 3.49Å; S385-D388 VanDerWaalsContact OG-CB 3.29Å; S385-D388 WeakPolarHBondContact OG-CB 3.45Å; S385-D388 PolarHBondContact OG-N 3.01Å; S385-D388 VanDerWaalsContact OG-N 3.16Å; S385-D388 PolarHBondContact OG-OD2 2.97Å; D388-E390 VanDerWaalsContact C-N 3.35Å; D388-E390 PolarHBondContact O-N 2.78Å; D388-Y391 WeakPolarHBondContact O-CB 3.48Å; D388-Y391 PolarHBondContact O-N 3.42Å; D388-L392 WeakPolarHBondContact O-CG 3.46Å; D388-L392 PolarHBondContact O-N 3.25Å; D388-Q444 PolarHBondContact OD2-NE2 3.16Å; D388-Q444 VanDerWaalsContact OD2-NE2 3.13Å; D388-L447 HydrophobicContact CB-CD1 3.56Å
389L64.8Low66.7Low38 Ų3858.4 Ų58.420%0.19928%0.284CS..Hα-helixtrans-62.4-39.7178.7-176.160.4000112.2T271 S385 T386 E387 Y391 L392 M393T271-L389 HydrophobicContact CG2-CD1 3.39Å; S385-L389 VanDerWaalsContact O-CB 3.23Å; S385-L389 WeakPolarHBondContact O-CB 3.42Å; S385-L389 PolarHBondContact O-N 2.75Å; T386-L389 PolarHBondContact O-N 3.46Å; E387-L389 VanDerWaalsContact C-N 3.28Å; E387-L389 PolarHBondContact O-N 3.35Å; L389-Y391 VanDerWaalsContact C-N 3.33Å; L389-Y391 PolarHBondContact O-N 3.31Å; L389-L392 PolarHBondContact O-N 3.13Å; L389-M393 HydrophobicContact CD1-CG 4.36Å; L389-M393 HydrophobicContact CG-CG 4.45Å; L389-M393 HydrophobicContact CG-SD 4.26Å; L389-M393 WeakPolarHBondContact O-CB 3.38Å; L389-M393 VanDerWaalsContact O-CG 3.24Å; L389-M393 WeakPolarHBondContact O-CG 3.34Å; L389-M393 PolarHBondContact O-N 3.28Å
390E65.9Low65.2Low144 Ų14463.4 Ų63.467%0.67332%0.315SS*.Hα-helixtrans-63-40.8174.7-72.6178-179.500111.4T386 E387 D388 M393 H394T386-E390 PolarHBondContact O-N 3.44Å; E387-E390 PolarHBondContact O-N 3.12Å; D388-E390 VanDerWaalsContact C-N 3.35Å; D388-E390 PolarHBondContact O-N 2.78Å; E390-M393 PolarHBondContact O-N 3.22Å; E390-H394 WeakPolarHBondContact O-CB 3.41Å; E390-H394 PolarHBondContact O-N 3.01Å
391Y64.8Low63.6Low169 Ų16968.1 Ų68.166%0.66334%0.344SS*.Hα-helixtrans-63.3-45.3172.7-80.5-77.2000112.3E387 D388 L389 M393 H394 A395E387-Y391 VanDerWaalsContact O-CD2 3.31Å; E387-Y391 WeakPolarHBondContact O-CD2 3.47Å; E387-Y391 PolarHBondContact O-N 3.12Å; D388-Y391 WeakPolarHBondContact O-CB 3.48Å; D388-Y391 PolarHBondContact O-N 3.42Å; L389-Y391 VanDerWaalsContact C-N 3.33Å; L389-Y391 PolarHBondContact O-N 3.31Å; Y391-M393 VanDerWaalsContact C-N 3.35Å; Y391-M393 PolarHBondContact O-N 3.07Å; Y391-H394 PolarHBondContact O-N 2.99Å; Y391-A395 VanDerWaalsContact O-CB 3.3Å; Y391-A395 WeakPolarHBondContact O-CB 3.29Å; Y391-A395 PolarHBondContact O-N 2.92Å
392L61.7Low62.1Low1 Ų169.6 Ų69.61%0.00535%0.353CS..Hα-helixtrans-59.9-45.6175.7-65.8178.4000110.6A384 D388 L389 H394 A395 K396 F442 L447A384-L392 HydrophobicContact CB-CD1 4.1Å; D388-L392 WeakPolarHBondContact O-CG 3.46Å; D388-L392 PolarHBondContact O-N 3.25Å; L389-L392 PolarHBondContact O-N 3.13Å; L392-H394 PolarHBondContact O-N 3.48Å; L392-A395 PolarHBondContact O-N 3.39Å; L392-K396 VanDerWaalsContact O-CB 3.28Å; L392-K396 WeakPolarHBondContact O-CB 3.49Å; L392-K396 WeakPolarHBondContact O-CG 3.42Å; L392-K396 PolarHBondContact O-N 2.92Å; L392-F442 HydrophobicContact CD2-CB 3.85Å; L392-F442 WeakPolarHBondContact CD2-O 3.22Å; L392-L447 HydrophobicContact CD1-CD1 4.17Å; L392-L447 HydrophobicContact CD2-CD1 3.43Å; L392-L447 VanDerWaalsContact CD2-CD1 3.43Å; L392-L447 HydrophobicContact CD2-CD2 4.14Å; L392-L447 HydrophobicContact CD2-CG 3.68Å; L392-L447 HydrophobicContact CG-CD1 3.59Å; L392-L447 HydrophobicContact CG-CG 4.39Å
393M61.2Low61Low114 Ų11472.2 Ų72.256%0.56238%0.375SS*.Hα-helixtrans-63.7-41.6179.2-73.5-177.373.800112.3L389 E390 Y391 K396 Q397L389-M393 HydrophobicContact CD1-CG 4.36Å; L389-M393 HydrophobicContact CG-CG 4.45Å; L389-M393 HydrophobicContact CG-SD 4.26Å; L389-M393 WeakPolarHBondContact O-CB 3.38Å; L389-M393 VanDerWaalsContact O-CG 3.24Å; L389-M393 WeakPolarHBondContact O-CG 3.34Å; L389-M393 PolarHBondContact O-N 3.28Å; E390-M393 PolarHBondContact O-N 3.22Å; Y391-M393 VanDerWaalsContact C-N 3.35Å; Y391-M393 PolarHBondContact O-N 3.07Å; M393-K396 WeakPolarHBondContact O-CB 2.96Å; M393-K396 PolarHBondContact O-N 2.81Å; M393-Q397 PolarHBondContact O-N 3.47Å
394H60.7Low60.3Low108 Ų10881.7 Ų81.750%0.542%0.416SS..Hα-helixtrans-66.1-42.9175.5-175.1-94.9000111.7E390 Y391 L392 Q397 Q398E390-H394 WeakPolarHBondContact O-CB 3.41Å; E390-H394 PolarHBondContact O-N 3.01Å; Y391-H394 PolarHBondContact O-N 2.99Å; L392-H394 PolarHBondContact O-N 3.48Å; H394-Q397 PolarHBondContact O-N 2.98Å; H394-Q398 PolarHBondContact CE1-NE2 2.92Å; H394-Q398 PolarHBondContact O-N 3.45Å
395A58.5Low60.3Low23 Ų2387.5 Ų87.519%0.1944%0.438CS..Hα-helixtrans-63.3-41.7174.800000111.8Y391 L392 Q397 Q398 L399 F442Y391-A395 VanDerWaalsContact O-CB 3.3Å; Y391-A395 WeakPolarHBondContact O-CB 3.29Å; Y391-A395 PolarHBondContact O-N 2.92Å; L392-A395 PolarHBondContact O-N 3.39Å; A395-Q397 PolarHBondContact O-N 2.78Å; A395-Q398 PolarHBondContact O-N 3.11Å; A395-L399 PolarHBondContact O-N 3.1Å; A395-F442 HydrophobicContact CB-CD1 3.94Å; A395-F442 HydrophobicContact CB-CD2 4.04Å; A395-F442 HydrophobicContact CB-CE1 3.75Å; A395-F442 HydrophobicContact CB-CE2 3.77Å; A395-F442 HydrophobicContact CB-CG 4.09Å; A395-F442 HydrophobicContact CB-CZ 3.66Å; A395-F442 VanDerWaalsContact O-CE2 3.24Å; A395-F442 WeakPolarHBondContact O-CE2 3.49Å
396K56.1Low60.4Low18 Ų1890.6 Ų90.68%0.07845%0.446CS..Hα-helixtrans-57.1-49.2173.6-76.2168.5177.2-151.10111.3L392 M393 Q398 L399 V400 A438 D439 F442L392-K396 VanDerWaalsContact O-CB 3.28Å; L392-K396 WeakPolarHBondContact O-CB 3.49Å; L392-K396 WeakPolarHBondContact O-CG 3.42Å; L392-K396 PolarHBondContact O-N 2.92Å; M393-K396 WeakPolarHBondContact O-CB 2.96Å; M393-K396 PolarHBondContact O-N 2.81Å; K396-Q398 PolarHBondContact O-N 3.41Å; K396-L399 PolarHBondContact O-N 3.32Å; K396-V400 VanDerWaalsContact O-CG2 3.3Å; K396-V400 WeakPolarHBondContact O-CG2 3.45Å; K396-V400 PolarHBondContact O-N 2.78Å; K396-A438 HydrophobicContact CB-CB 4.15Å; K396-A438 HydrophobicContact CG-CB 4.07Å; K396-D439 VanDerWaalsContact CD-OD1 3.25Å; K396-D439 WeakPolarHBondContact CD-OD1 3.25Å; K396-D439 VanDerWaalsContact CE-OD1 3.28Å; K396-D439 WeakPolarHBondContact CE-OD1 3.35Å; K396-D439 IonicContact NZ-OD1 2.98Å; K396-D439 PolarHBondContact NZ-OD1 2.94Å; K396-F442 HydrophobicContact CB-CD2 4.48Å; K396-F442 HydrophobicContact CG-CB 4.15Å; K396-F442 HydrophobicContact CG-CD2 3.85Å; K396-F442 HydrophobicContact CG-CG 4.46Å
397Q53.9Low60.4Low147 Ų14787.8 Ų87.869%0.68743%0.428SS*.Hα-helixtrans-56.5-33.8178-106.6175.7-4.800113.2M393 H394 A395M393-Q397 PolarHBondContact O-N 3.47Å; H394-Q397 PolarHBondContact O-N 2.98Å; A395-Q397 PolarHBondContact O-N 2.78Å
398Q54Low60.4Low116 Ų11685.4 Ų85.454%0.54243%0.427SS..Hα-helixtrans-74.4-20.2176.9-65.8-1712.100114.4H394 A395 K396 T401 K473H394-Q398 PolarHBondContact CE1-NE2 2.92Å; H394-Q398 PolarHBondContact O-N 3.45Å; A395-Q398 PolarHBondContact O-N 3.11Å; K396-Q398 PolarHBondContact O-N 3.41Å; Q398-T401 PolarHBondContact O-OG1 3.45Å; Q398-K473 PolarHBondContact O-NZ 3.01Å
399L51.5Low60.4Low30 Ų3086.6 Ų86.616%0.15744%0.439CS..Hα-helixtrans-94.1-27.5176.2-76.9-170.6000114A395 K396 T401 T402 A438 F442 I469A395-L399 PolarHBondContact O-N 3.1Å; K396-L399 PolarHBondContact O-N 3.32Å; L399-T401 PolarHBondContact O-N 2.97Å; L399-T402 PolarHBondContact O-N 3.31Å; L399-T402 PolarHBondContact O-OG1 3.39Å; L399-A438 HydrophobicContact CB-CB 3.84Å; L399-A438 HydrophobicContact CD1-CB 4.31Å; L399-F442 HydrophobicContact CB-CE2 4.21Å; L399-F442 HydrophobicContact CD1-CD2 3.92Å; L399-F442 HydrophobicContact CD1-CE2 3.06Å; L399-F442 HydrophobicContact CD1-CZ 3.48Å; L399-F442 VanDerWaalsContact CD1-CZ 3.48Å; L399-F442 HydrophobicContact CG-CE2 3.52Å; L399-F442 HydrophobicContact CG-CZ 3.91Å; L399-I469 HydrophobicContact CD1-CG2 4.3Å; L399-I469 HydrophobicContact CD2-CG2 4.03Å
400V48.9Very low60.7Low108 Ų10886.9 Ų86.966%0.65544%0.444SS*.THydrogen-bonded Turntrans-61.8-10.8-178.8169.90000113.5K396 T402 A438K396-V400 VanDerWaalsContact O-CG2 3.3Å; K396-V400 WeakPolarHBondContact O-CG2 3.45Å; K396-V400 PolarHBondContact O-N 2.78Å; V400-T402 VanDerWaalsContact C-N 3.32Å; V400-T402 PolarHBondContact O-N 3.24Å; V400-A438 HydrophobicContact CG2-CB 4.31Å
401T45.4Very low61.4Low113 Ų11381.9 Ų81.969%0.69342%0.42SS*.THydrogen-bonded Turntrans-83.44177.333.60000115.2Q398 L399Q398-T401 PolarHBondContact O-OG1 3.45Å; L399-T401 PolarHBondContact O-N 2.97Å
402T49.3Very low62.3Low30 Ų3076.7 Ų76.718%0.18441%0.406CS..SBendtrans-89.2128.6-177.9-37.40000110.6L399 V400 K404 Y472 K473L399-T402 PolarHBondContact O-N 3.31Å; L399-T402 PolarHBondContact O-OG1 3.39Å; V400-T402 VanDerWaalsContact C-N 3.32Å; V400-T402 PolarHBondContact O-N 3.24Å; T402-K404 PolarHBondContact O-N 3.12Å; T402-Y472 HydrophobicContact CG2-CD1 3.73Å; T402-Y472 HydrophobicContact CG2-CE1 3.7Å; T402-K473 HydrophobicContact CG2-CB 3.86Å; T402-K473 HydrophobicContact CG2-CG 4.05Å
403A49.9Very low63.4Low56 Ų5678.7 Ų78.746%0.46342%0.417SS..  trans-51.4140179.300000111.5R405 Y472A403-R405 PolarHBondContact O-N 3.06Å; A403-R405 VanDerWaalsContact O-N 3.08Å; A403-Y472 WeakPolarHBondContact O-CE1 3.33Å; A403-Y472 PolarHBondContact O-OH 3.4Å
404K63.6Low64.6Low199 Ų19976.1 Ų76.187%0.86540%0.404SS*.  trans-57.7115.5179-86.9-172.9174.3-175.10110.4T402T402-K404 PolarHBondContact O-N 3.12Å
405R72.4Confident65.7Low121 Ų12175.2 Ų75.246%0.45740%0.404SS..  trans-56.1134171.3-176.6173176166.6-2.7110A403 Y472A403-R405 PolarHBondContact O-N 3.06Å; A403-R405 VanDerWaalsContact O-N 3.08Å; R405-Y472 WeakPolarHBondContact CA-OH 3.4Å; R405-Y472 HydrophobicContact CB-CE1 4.1Å; R405-Y472 HydrophobicContact CB-CE2 4.03Å; R405-Y472 HydrophobicContact CG-CE2 3.91Å; R405-Y472 PolarHBondContact N-OH 2.9Å
406W77.1Confident66.9Low89 Ų8977.1 Ų77.134%0.33741%0.407SS..  trans-73.7127.8168.4-64.2-16.1000109K411 Y535 L537 V554W406-K411 HydrophobicContact CB-CG 4.21Å; W406-K411 HydrophobicContact CG-CG 4.04Å; W406-Y535 HydrophobicContact CE3-CG 4.46Å; W406-L537 HydrophobicContact CH2-CB 3.42Å; W406-L537 VanDerWaalsContact CH2-CB 3.42Å; W406-L537 HydrophobicContact CH2-CD2 4.29Å; W406-L537 HydrophobicContact CZ2-CB 3.99Å; W406-L537 HydrophobicContact CZ2-CD2 3.98Å; W406-L537 HydrophobicContact CZ3-CB 4Å; W406-V554 HydrophobicContact CD2-CG1 4.42Å; W406-V554 HydrophobicContact CD2-CG2 4.12Å; W406-V554 HydrophobicContact CE3-CB 4.35Å; W406-V554 HydrophobicContact CE3-CG1 3.49Å; W406-V554 VanDerWaalsContact CE3-CG1 3.49Å; W406-V554 HydrophobicContact CE3-CG2 3.87Å; W406-V554 HydrophobicContact CZ3-CG1 3.79Å; W406-V554 HydrophobicContact CZ3-CG2 4.2Å
407D72.8Confident67.8Low29 Ų2984.1 Ų84.116%0.15544%0.44CS..  trans-143.6174.5-178.665.7-2.2000109S409 S410 K411 L436D407-S409 PolarHBondContact O-N 3.44Å; D407-S409 PolarHBondContact OD1-N 3.43Å; D407-S409 PolarHBondContact OD1-OG 2.93Å; D407-S409 PolarHBondContact OD2-OG 3.2Å; D407-S410 PolarHBondContact N-OG 3.28Å; D407-S410 PolarHBondContact O-N 3.05Å; D407-S410 PolarHBondContact O-OG 3.37Å; D407-S410 WeakPolarHBondContact OD1-CB 3.39Å; D407-S410 PolarHBondContact OD1-N 2.91Å; D407-S410 PolarHBondContact OD1-OG 3.31Å; D407-K411 PolarHBondContact O-N 3.35Å; D407-L436 WeakPolarHBondContact OD2-CD2 3.49Å
408S68.8Low68.5Low93 Ų9381.6 Ų81.665%0.6544%0.437SS*.THydrogen-bonded Turntrans-64.5-21177.255.70000113K411 K551S408-K411 WeakPolarHBondContact CA-O 3.45Å; S408-K551 PolarHBondContact O-NZ 3.07Å
409S66.4Low69.1Low72 Ų7279.1 Ų79.150%0.50343%0.428SS..THydrogen-bonded Turntrans-71.9-38.4175.988.40000111.6D407 K551D407-S409 PolarHBondContact O-N 3.44Å; D407-S409 PolarHBondContact OD1-N 3.43Å; D407-S409 PolarHBondContact OD1-OG 2.93Å; D407-S409 PolarHBondContact OD2-OG 3.2Å; S409-K551 WeakPolarHBondContact O-CE 3.43Å; S409-K551 PolarHBondContact O-NZ 2.46Å
410S71.4Confident69.8Low45 Ų4586.6 Ų86.632%0.31546%0.462SS..THydrogen-bonded Turntrans-98.5-30.6-174.560.60000114.8D407D407-S410 PolarHBondContact N-OG 3.28Å; D407-S410 PolarHBondContact O-N 3.05Å; D407-S410 PolarHBondContact O-OG 3.37Å; D407-S410 WeakPolarHBondContact OD1-CB 3.39Å; D407-S410 PolarHBondContact OD1-N 2.91Å; D407-S410 PolarHBondContact OD1-OG 3.31Å
411K81.3Confident70.7Confident38 Ų3883.5 Ų83.517%0.16544%0.443CS..SBendtrans-138161-174.6-59.9-65.8176.7-1680111.6W406 D407 S408 E552 V554W406-K411 HydrophobicContact CB-CG 4.21Å; W406-K411 HydrophobicContact CG-CG 4.04Å; D407-K411 PolarHBondContact O-N 3.35Å; S408-K411 WeakPolarHBondContact CA-O 3.45Å; K411-E552 HydrophobicContact CD-CB 3.89Å; K411-E552 IonicContact NZ-OE2 2.59Å; K411-E552 PolarHBondContact NZ-OE2 3.02Å; K411-V554 HydrophobicContact CB-CB 4.41Å; K411-V554 HydrophobicContact CB-CG2 3.79Å; K411-V554 HydrophobicContact CD-CG2 4.02Å; K411-V554 HydrophobicContact CG-CG2 3.76Å
412T84.1Confident72.2Confident60 Ų6081.6 Ų81.637%0.36843%0.431SS..EExtended strand (participates in β ladder)trans-91.2105.4166.2-59.90000107.9E552 K553 V554T412-E552 PolarHBondContact N-O 3.01Å; T412-K553 HydrophobicContact CG2-CG 4.49Å; T412-K553 WeakPolarHBondContact O-CA 3.25Å; T412-V554 PolarHBondContact O-N 3.44Å
413I84.9Confident73.4Confident43 Ų4385.1 Ų85.122%0.22145%0.449CS..EExtended strand (participates in β ladder)trans-82.7131.7178.5-58.1174.1000108.6Y535 V554I413-Y535 HydrophobicContact CG2-CD1 4.27Å; I413-Y535 HydrophobicContact CG2-CE1 3.51Å; I413-V554 CarbonylContact C-O 3.55Å; I413-V554 WeakPolarHBondContact CA-O 3.35Å
414I86.4Confident74.6Confident60 Ų6087.2 Ų87.231%0.30845%0.452SS..EExtended strand (participates in β ladder)trans-114.2108.2175.6-61.4173.6000106.4K553 V554 Y555 E556I414-K553 HydrophobicContact CD1-CB 4.1Å; I414-K553 HydrophobicContact CD1-CD 3.93Å; I414-K553 HydrophobicContact CD1-CG 4.17Å; I414-V554 PolarHBondContact N-O 2.96Å; I414-Y555 HydrophobicContact CB-CD1 3.94Å; I414-Y555 HydrophobicContact CB-CE1 4.34Å; I414-Y555 HydrophobicContact CD1-CD1 3.86Å; I414-Y555 HydrophobicContact CD1-CE1 3.36Å; I414-Y555 HydrophobicContact CG1-CD1 4.45Å; I414-Y555 HydrophobicContact CG1-CE1 4.4Å; I414-Y555 HydrophobicContact CG2-CD1 4.02Å; I414-Y555 HydrophobicContact CG2-CE1 4.36Å; I414-E556 PolarHBondContact O-N 2.66Å
415D83.8Confident75.1Confident90 Ų9082.1 Ų82.148%0.48143%0.431SS..  trans-68.2156.3-177.2-57.7-21.3000111.6E556D415-E556 WeakPolarHBondContact CA-OE2 3.36Å
416F82.5Confident75.1Confident62 Ų6280.2 Ų80.227%0.27243%0.426SS..  trans-78.2134.9176-178.5-95.1000111.1E556 T558F416-E556 HydrophobicContact CB-CB 4.38Å; F416-E556 HydrophobicContact CB-CG 4.4Å; F416-E556 PolarHBondContact N-OE2 3.39Å; F416-E556 VanDerWaalsContact N-OE2 3.09Å; F416-T558 HydrophobicContact CB-CG2 4.21Å; F416-T558 HydrophobicContact CD1-CG2 3.53Å; F416-T558 HydrophobicContact CE1-CG2 4.01Å; F416-T558 HydrophobicContact CG-CG2 3.88Å
417E76.4Confident74.9Confident165 Ų16576 Ų7677%0.77141%0.411SS*.SBendtrans-111134.3172.5-67.3-174.8169.100110.5
418P68.5Low75.1Confident95 Ų9579 Ų7962%0.61743%0.426SS*.SBendcis-80.3132.48.630.4-33.2000113.2
419N64.9Low75.4Confident64 Ų6480.2 Ų80.234%0.34243%0.425SS..  trans-94.3112.2177.7-166.7-11000109.4T421N419-T421 PolarHBondContact ND2-OG1 3.01Å; N419-T421 VanDerWaalsContact ND2-OG1 3.07Å; N419-T421 PolarHBondContact O-N 2.96Å; N419-T421 WeakPolarHBondContact OD1-CB 3.45Å; N419-T421 WeakPolarHBondContact OD1-CG2 3.43Å; N419-T421 PolarHBondContact OD1-N 3.35Å; N419-T421 VanDerWaalsContact OD1-N 3.07Å; N419-T421 PolarHBondContact OD1-OG1 3.17Å
420E66.1Low75.6Confident187 Ų18780 Ų8087%0.87442%0.417SS*.  trans-78.6-2.9177.4-65.2-170.6164.400113T422E420-T422 PolarHBondContact O-N 3.43Å
421T68.6Low75.6Confident43 Ų4381 Ų8126%0.26441%0.414SS..  trans-63.7124.2178.352.50000111.2N419 E425 K426N419-T421 PolarHBondContact ND2-OG1 3.01Å; N419-T421 VanDerWaalsContact ND2-OG1 3.07Å; N419-T421 PolarHBondContact O-N 2.96Å; N419-T421 WeakPolarHBondContact OD1-CB 3.45Å; N419-T421 WeakPolarHBondContact OD1-CG2 3.43Å; N419-T421 PolarHBondContact OD1-N 3.35Å; N419-T421 VanDerWaalsContact OD1-N 3.07Å; N419-T421 PolarHBondContact OD1-OG1 3.17Å; T421-E425 WeakPolarHBondContact CA-OE2 3.42Å; T421-K426 WeakPolarHBondContact O-CE 3.41Å; T421-K426 WeakPolarHBondContact OG1-CE 3.47Å
422T77.2Confident75.3Confident73 Ų7382.8 Ų82.845%0.44842%0.42SS..  trans-65.4154.7174.560.20000110.4E420 L424 E425 K426E420-T422 PolarHBondContact O-N 3.43Å; T422-L424 PolarHBondContact O-N 2.51Å; T422-L424 VanDerWaalsContact O-N 3.17Å; T422-E425 PolarHBondContact N-OE2 3.11Å; T422-E425 PolarHBondContact O-N 2.69Å; T422-E425 VanDerWaalsContact OG1-CD 3.3Å; T422-E425 VanDerWaalsContact OG1-CG 3.27Å; T422-E425 WeakPolarHBondContact OG1-CG 3.43Å; T422-E425 PolarHBondContact OG1-N 3.33Å; T422-E425 PolarHBondContact OG1-OE2 3.11Å; T422-K426 PolarHBondContact O-N 3.07Å; T422-K426 VanDerWaalsContact O-N 3.08Å
423D74.2Confident74.5Confident103 Ų10384.3 Ų84.355%0.55142%0.423SS*.Hα-helixtrans-59.1-29.7175.5-65.5-28.6000111.9S427D423-S427 WeakPolarHBondContact O-CB 3.38Å; D423-S427 PolarHBondContact O-N 3.46Å
424L74.5Confident73.5Confident101 Ų10183.9 Ų83.953%0.52942%0.421SS..Hα-helixtrans-63.3-49.4173.1-179.262000111.7T422 K426 S427 L428T422-L424 PolarHBondContact O-N 2.51Å; T422-L424 VanDerWaalsContact O-N 3.17Å; L424-K426 PolarHBondContact O-N 3.19Å; L424-S427 WeakPolarHBondContact O-CB 3.34Å; L424-S427 PolarHBondContact O-N 3.48Å; L424-S427 PolarHBondContact O-OG 3.19Å; L424-L428 HydrophobicContact CG-CD1 4.4Å; L424-L428 WeakPolarHBondContact O-CG 3.09Å; L424-L428 PolarHBondContact O-N 3.08Å
425E74.3Confident72.4Confident91 Ų9181.9 Ų81.943%0.42541%0.412SS..Hα-helixtrans-62.4-42.4179.2-73.2163141.100111.9T421 T422 S427 L428 L429T421-E425 WeakPolarHBondContact CA-OE2 3.42Å; T422-E425 PolarHBondContact N-OE2 3.11Å; T422-E425 PolarHBondContact O-N 2.69Å; T422-E425 VanDerWaalsContact OG1-CD 3.3Å; T422-E425 VanDerWaalsContact OG1-CG 3.27Å; T422-E425 WeakPolarHBondContact OG1-CG 3.43Å; T422-E425 PolarHBondContact OG1-N 3.33Å; T422-E425 PolarHBondContact OG1-OE2 3.11Å; E425-S427 VanDerWaalsContact C-N 3.31Å; E425-S427 PolarHBondContact O-N 3.19Å; E425-L428 PolarHBondContact O-N 3.33Å; E425-L428 VanDerWaalsContact O-N 3.15Å; E425-L429 WeakPolarHBondContact O-CG 3.27Å; E425-L429 PolarHBondContact O-N 3.36Å
426K73.9Confident71Confident82 Ų8283.1 Ų83.136%0.35742%0.418SS..Hα-helixtrans-57.2-46.2173.4-67.3175.3-172.3163.30111.1T421 T422 L424 L428 L429 I430T421-K426 WeakPolarHBondContact O-CE 3.41Å; T421-K426 WeakPolarHBondContact OG1-CE 3.47Å; T422-K426 PolarHBondContact O-N 3.07Å; T422-K426 VanDerWaalsContact O-N 3.08Å; L424-K426 PolarHBondContact O-N 3.19Å; K426-L428 VanDerWaalsContact C-N 3.29Å; K426-L428 PolarHBondContact O-N 2.98Å; K426-L429 PolarHBondContact O-N 3.49Å; K426-I430 VanDerWaalsContact O-CG1 3.3Å; K426-I430 WeakPolarHBondContact O-CG1 3.47Å; K426-I430 PolarHBondContact O-N 3.49Å; K426-I430 VanDerWaalsContact O-N 3.08Å
427S72.8Confident69.8Low1 Ų182.1 Ų82.11%0.00742%0.419CS..Hα-helixtrans-63.4-32.5178.3840000113.3L247 D423 L424 E425 R431L247-S427 WeakPolarHBondContact O-CB 3.3Å; D423-S427 WeakPolarHBondContact O-CB 3.38Å; D423-S427 PolarHBondContact O-N 3.46Å; L424-S427 WeakPolarHBondContact O-CB 3.34Å; L424-S427 PolarHBondContact O-N 3.48Å; L424-S427 PolarHBondContact O-OG 3.19Å; E425-S427 VanDerWaalsContact C-N 3.31Å; E425-S427 PolarHBondContact O-N 3.19Å; S427-R431 WeakPolarHBondContact O-CG 3.46Å; S427-R431 PolarHBondContact O-N 3.37Å; S427-R431 PolarHBondContact O-NE 3.07Å; S427-R431 VanDerWaalsContact O-NE 3.07Å; S427-R431 PolarHBondContact OG-NH2 3.39Å
428L77.1Confident68.6Low91 Ų9174.7 Ų74.748%0.47639%0.385SS..Hα-helixtrans-74.1-43177.9-71.8173.1000111L424 E425 K426 I430 R431 Y432L424-L428 HydrophobicContact CG-CD1 4.4Å; L424-L428 WeakPolarHBondContact O-CG 3.09Å; L424-L428 PolarHBondContact O-N 3.08Å; E425-L428 PolarHBondContact O-N 3.33Å; E425-L428 VanDerWaalsContact O-N 3.15Å; K426-L428 VanDerWaalsContact C-N 3.29Å; K426-L428 PolarHBondContact O-N 2.98Å; L428-I430 VanDerWaalsContact C-N 3.26Å; L428-I430 PolarHBondContact O-N 3.03Å; L428-R431 PolarHBondContact O-N 2.84Å; L428-R431 VanDerWaalsContact O-N 3.15Å; L428-Y432 WeakPolarHBondContact O-CB 3.09Å; L428-Y432 PolarHBondContact O-N 2.92Å
429L74.3Confident67.9Low119 Ų11973.7 Ų73.762%0.62338%0.375SS*.Hα-helixtrans-62.1-34176.4-72.3169.2000112.4E425 K426E425-L429 WeakPolarHBondContact O-CG 3.27Å; E425-L429 PolarHBondContact O-N 3.36Å; K426-L429 PolarHBondContact O-N 3.49Å
430I71.2Confident67.6Low68 Ų6873.8 Ų73.835%0.34937%0.373SS..Hα-helixtrans-70.8-37.6175.5-66.5168000111.5E250 K426 L428E250-I430 HydrophobicContact CB-CG2 4.06Å; E250-I430 WeakPolarHBondContact OE2-CD1 3.44Å; E250-I430 WeakPolarHBondContact OE2-CG2 3.27Å; K426-I430 VanDerWaalsContact O-CG1 3.3Å; K426-I430 WeakPolarHBondContact O-CG1 3.47Å; K426-I430 PolarHBondContact O-N 3.49Å; K426-I430 VanDerWaalsContact O-N 3.08Å; L428-I430 VanDerWaalsContact C-N 3.26Å; L428-I430 PolarHBondContact O-N 3.03Å
431R70.6Confident67.2Low64 Ų6464.9 Ų64.924%0.24233%0.332CS..Hα-helixtrans-71-37.8177.2-75.5-179-92.9-167.9-11112.3W243 M244 P249 S427 L428 Q433W243-R431 HydrophobicContact CH2-CG 4.27Å; W243-R431 HydrophobicContact CZ2-CB 4.47Å; W243-R431 HydrophobicContact CZ2-CG 3.87Å; M244-R431 PolarHBondContact O-NH1 3.12Å; P249-R431 HydrophobicContact CB-CG 4.03Å; P249-R431 HydrophobicContact CG-CG 3.85Å; S427-R431 WeakPolarHBondContact O-CG 3.46Å; S427-R431 PolarHBondContact O-N 3.37Å; S427-R431 PolarHBondContact O-NE 3.07Å; S427-R431 VanDerWaalsContact O-NE 3.07Å; S427-R431 PolarHBondContact OG-NH2 3.39Å; L428-R431 PolarHBondContact O-N 2.84Å; L428-R431 VanDerWaalsContact O-N 3.15Å; R431-Q433 PolarHBondContact O-N 3.48Å
432Y74.1Confident66.8Low77 Ų7764.2 Ų64.230%0.30233%0.325SS..  trans-86.7102-177.9-174.4-102.8000111L428 I434 L464 Y465 E468L428-Y432 WeakPolarHBondContact O-CB 3.09Å; L428-Y432 PolarHBondContact O-N 2.92Å; Y432-I434 HydrophobicContact CD1-CG1 4.27Å; Y432-I434 HydrophobicContact CE1-CD1 4.08Å; Y432-I434 HydrophobicContact CE1-CG1 3.55Å; Y432-L464 HydrophobicContact CE2-CD2 4.32Å; Y432-L464 WeakPolarHBondContact OH-CD2 3.29Å; Y432-Y465 AromaticContact CE2-CE1 3.7Å; Y432-Y465 HydrophobicContact CE2-CE1 3.7Å; Y432-Y465 AromaticContact CZ-CE1 3.77Å; Y432-Y465 WeakPolarHBondContact OH-CD1 3.08Å; Y432-Y465 VanDerWaalsContact OH-CE1 3.31Å; Y432-Y465 WeakPolarHBondContact OH-CE1 3.38Å; Y432-E468 PolarHBondContact OH-OE1 2.96Å; Y432-E468 PolarHBondContact OH-OE2 3.2Å
433Q67.4Low66.3Low91 Ų9160.7 Ų60.743%0.42530%0.304SS..  trans-111.2126173.8-64.1-156.42.800111.2R431R431-Q433 PolarHBondContact O-N 3.48Å
434I64.8Low65.8Low35 Ų3556.3 Ų56.318%0.17928%0.28CS..  trans-76.8128177-57.7173.4000107.4Y432 L436 E468 I469Y432-I434 HydrophobicContact CD1-CG1 4.27Å; Y432-I434 HydrophobicContact CE1-CD1 4.08Å; Y432-I434 HydrophobicContact CE1-CG1 3.55Å; I434-L436 PolarHBondContact O-N 3.29Å; I434-E468 WeakPolarHBondContact CD1-OE2 3.35Å; I434-E468 WeakPolarHBondContact CG1-OE2 3.41Å; I434-I469 HydrophobicContact CG2-CD1 4.16Å; I434-I469 HydrophobicContact CG2-CG1 4.23Å
435P62.8Low65.4Low17 Ų1751.8 Ų51.811%0.1126%0.256CS..  trans-58.1129.5179.7-20.429.7000111.5S437 Q440 L441 Y465P435-S437 VanDerWaalsContact C-N 3.29Å; P435-S437 PolarHBondContact O-N 2.9Å; P435-Q440 HydrophobicContact CB-CB 3.49Å; P435-Q440 VanDerWaalsContact CB-CB 3.49Å; P435-Q440 HydrophobicContact CB-CG 4.48Å; P435-L441 HydrophobicContact CB-CD2 3.74Å; P435-L441 HydrophobicContact CB-CG 4.04Å; P435-L441 HydrophobicContact CG-CD2 3.69Å; P435-L441 HydrophobicContact CG-CG 4.49Å; P435-Y465 VanDerWaalsContact CD-CG 3.48Å; P435-Y465 HydrophobicContact CG-CD1 4.12Å; P435-Y465 HydrophobicContact CG-CD2 3.6Å; P435-Y465 HydrophobicContact CG-CE1 4.32Å; P435-Y465 HydrophobicContact CG-CE2 3.86Å; P435-Y465 HydrophobicContact CG-CG 3.76Å
436L55.3Low65.1Low117 Ų11748.8 Ų48.861%0.61324%0.244SC*.SBendtrans-81.2-5-165.3-68.6167.6000113.8D407 I434D407-L436 WeakPolarHBondContact OD2-CD2 3.49Å; I434-L436 PolarHBondContact O-N 3.29Å
437S55.9Low64.7Low41 Ų4147.4 Ų47.429%0.28724%0.241SC..SBendtrans-145.3151.3-176.262.20000112.6P435 D439 Q440 L441P435-S437 VanDerWaalsContact C-N 3.29Å; P435-S437 PolarHBondContact O-N 2.9Å; S437-D439 PolarHBondContact O-N 3.49Å; S437-D439 VanDerWaalsContact O-N 3.12Å; S437-Q440 PolarHBondContact O-N 3.47Å; S437-L441 WeakPolarHBondContact O-CD1 3.42Å; S437-L441 WeakPolarHBondContact O-CG 3.44Å
438A53.2Low64.7Low9 Ų949.7 Ų49.77%0.07425%0.253CS..G310 helixtrans-52.3-30.1171.800000112.6K396 L399 V400 Q440 L441 F442K396-A438 HydrophobicContact CB-CB 4.15Å; K396-A438 HydrophobicContact CG-CB 4.07Å; L399-A438 HydrophobicContact CB-CB 3.84Å; L399-A438 HydrophobicContact CD1-CB 4.31Å; V400-A438 HydrophobicContact CG2-CB 4.31Å; A438-Q440 PolarHBondContact O-N 2.92Å; A438-L441 PolarHBondContact O-N 3.43Å; A438-F442 HydrophobicContact CB-CD2 4.39Å; A438-F442 PolarHBondContact O-N 3.04Å; A438-F442 VanDerWaalsContact O-N 3.15Å
439D51.8Low64.4Low74 Ų7455.5 Ų55.540%0.39627%0.274SS..G310 helixtrans-63.6-25.8176.5-64.4-47.5000113.7K396 S437K396-D439 VanDerWaalsContact CD-OD1 3.25Å; K396-D439 WeakPolarHBondContact CD-OD1 3.25Å; K396-D439 VanDerWaalsContact CE-OD1 3.28Å; K396-D439 WeakPolarHBondContact CE-OD1 3.35Å; K396-D439 IonicContact NZ-OD1 2.98Å; K396-D439 PolarHBondContact NZ-OD1 2.94Å; S437-D439 PolarHBondContact O-N 3.49Å; S437-D439 VanDerWaalsContact O-N 3.12Å
440Q59.1Low64.4Low65 Ų6553.3 Ų53.330%0.30427%0.269SS..G310 helixtrans-92.1-5.3-180-63.8174.2-16.300114.8R362 M380 P435 S437 A438R362-Q440 PolarHBondContact NH2-O 3.31Å; M380-Q440 VanDerWaalsContact CE-CA 3.45Å; M380-Q440 HydrophobicContact CE-CB 3.93Å; M380-Q440 HydrophobicContact CE-CG 3.78Å; P435-Q440 HydrophobicContact CB-CB 3.49Å; P435-Q440 VanDerWaalsContact CB-CB 3.49Å; P435-Q440 HydrophobicContact CB-CG 4.48Å; S437-Q440 PolarHBondContact O-N 3.47Å; A438-Q440 PolarHBondContact O-N 2.92Å
441L58.3Low64.9Low1 Ų154.7 Ų54.71%0.00528%0.277CS..THydrogen-bonded Turntrans-117.4-36.1-167-61.9156.9000112.5P435 S437 A438 T443 V446 Y465 I466 I469P435-L441 HydrophobicContact CB-CD2 3.74Å; P435-L441 HydrophobicContact CB-CG 4.04Å; P435-L441 HydrophobicContact CG-CD2 3.69Å; P435-L441 HydrophobicContact CG-CG 4.49Å; S437-L441 WeakPolarHBondContact O-CD1 3.42Å; S437-L441 WeakPolarHBondContact O-CG 3.44Å; A438-L441 PolarHBondContact O-N 3.43Å; L441-T443 VanDerWaalsContact C-N 3.28Å; L441-T443 PolarHBondContact O-N 3.02Å; L441-V446 WeakPolarHBondContact O-CG2 3.26Å; L441-Y465 HydrophobicContact CD2-CD2 4.46Å; L441-Y465 HydrophobicContact CD2-CG 4.13Å; L441-I466 HydrophobicContact CB-CG1 4.38Å; L441-I469 HydrophobicContact CD1-CD1 2.99Å; L441-I469 HydrophobicContact CD1-CG1 4.36Å; L441-I469 HydrophobicContact CD2-CD1 3.73Å; L441-I469 HydrophobicContact CG-CD1 3.96Å
442F60.7Low65.2Low28 Ų2854.4 Ų54.412%0.12328%0.282CS..SBendtrans-91.375.9173.5-70.6-60.3000108.9L392 A395 K396 L399 A438 I466L392-F442 HydrophobicContact CD2-CB 3.85Å; L392-F442 WeakPolarHBondContact CD2-O 3.22Å; A395-F442 HydrophobicContact CB-CD1 3.94Å; A395-F442 HydrophobicContact CB-CD2 4.04Å; A395-F442 HydrophobicContact CB-CE1 3.75Å; A395-F442 HydrophobicContact CB-CE2 3.77Å; A395-F442 HydrophobicContact CB-CG 4.09Å; A395-F442 HydrophobicContact CB-CZ 3.66Å; A395-F442 VanDerWaalsContact O-CE2 3.24Å; A395-F442 WeakPolarHBondContact O-CE2 3.49Å; K396-F442 HydrophobicContact CB-CD2 4.48Å; K396-F442 HydrophobicContact CG-CB 4.15Å; K396-F442 HydrophobicContact CG-CD2 3.85Å; K396-F442 HydrophobicContact CG-CG 4.46Å; L399-F442 HydrophobicContact CB-CE2 4.21Å; L399-F442 HydrophobicContact CD1-CD2 3.92Å; L399-F442 HydrophobicContact CD1-CE2 3.06Å; L399-F442 HydrophobicContact CD1-CZ 3.48Å; L399-F442 VanDerWaalsContact CD1-CZ 3.48Å; L399-F442 HydrophobicContact CG-CE2 3.52Å; L399-F442 HydrophobicContact CG-CZ 3.91Å; A438-F442 HydrophobicContact CB-CD2 4.39Å; A438-F442 PolarHBondContact O-N 3.04Å; A438-F442 VanDerWaalsContact O-N 3.15Å; F442-I466 HydrophobicContact CD1-CD1 4.41Å; F442-I466 HydrophobicContact CE1-CD1 4.3Å
443T65.9Low65.4Low0 Ų061 Ų610%031%0.312CS..  trans-95.1159.7178.3500000109.5T360 D382 L441 S445 V446 D462T360-T443 HydrophobicContact CG2-CG2 3.69Å; T360-T443 VanDerWaalsContact OG1-CB 3.22Å; T360-T443 WeakPolarHBondContact OG1-CB 3.33Å; D382-T443 WeakPolarHBondContact OD1-CA 3.15Å; D382-T443 WeakPolarHBondContact OD1-CB 3.39Å; D382-T443 WeakPolarHBondContact OD1-CG2 3.25Å; L441-T443 VanDerWaalsContact C-N 3.28Å; L441-T443 PolarHBondContact O-N 3.02Å; T443-S445 WeakPolarHBondContact CB-OG 3.32Å; T443-S445 PolarHBondContact O-N 3.25Å; T443-S445 PolarHBondContact OG1-OG 3.11Å; T443-V446 WeakPolarHBondContact O-CB 3.45Å; T443-V446 PolarHBondContact O-N 3.32Å; T443-D462 PolarHBondContact OG1-OD2 3.49Å; T443-D462 VanDerWaalsContact OG1-OD2 3.05Å
444Q63.7Low65.7Low11 Ų1162.1 Ų62.15%0.05133%0.33CS..Hα-helixtrans-59.5-32179.9-178.263.86.600112.3F358 T360 D388 V446 L447 D448F358-Q444 HydrophobicContact CB-CG 4.42Å; T360-Q444 PolarHBondContact OG1-N 3.49Å; D388-Q444 PolarHBondContact OD2-NE2 3.16Å; D388-Q444 VanDerWaalsContact OD2-NE2 3.13Å; Q444-V446 PolarHBondContact O-N 2.94Å; Q444-V446 VanDerWaalsContact O-N 3.13Å; Q444-L447 PolarHBondContact O-N 3.47Å; Q444-D448 PolarHBondContact O-N 2.92Å
445S66.6Low66.2Low5 Ų561.4 Ų61.44%0.03533%0.327CS..Hα-helixtrans-54-29.3174.752.20000113.8T443 R459 D462T443-S445 WeakPolarHBondContact CB-OG 3.32Å; T443-S445 PolarHBondContact O-N 3.25Å; T443-S445 PolarHBondContact OG1-OG 3.11Å; S445-R459 VanDerWaalsContact O-CD 3.25Å; S445-R459 WeakPolarHBondContact O-CD 3.24Å; S445-R459 WeakPolarHBondContact O-CG 3.47Å; S445-D462 PolarHBondContact OG-OD2 3.43Å
446V66.9Low67.1Low28 Ų2867 Ų6717%0.1735%0.346CS..Hα-helixtrans-75-32178.3177.90000111.2L441 T443 Q444 D462 I466L441-V446 WeakPolarHBondContact O-CG2 3.26Å; T443-V446 WeakPolarHBondContact O-CB 3.45Å; T443-V446 PolarHBondContact O-N 3.32Å; Q444-V446 PolarHBondContact O-N 2.94Å; Q444-V446 VanDerWaalsContact O-N 3.13Å; V446-D462 HydrophobicContact CG2-CB 3.6Å; V446-I466 HydrophobicContact CB-CD1 4.37Å; V446-I466 HydrophobicContact CG1-CD1 3.68Å; V446-I466 HydrophobicContact CG2-CD1 3.73Å
447L67.3Low68.2Low54 Ų5468.2 Ų68.228%0.28335%0.349SS..Hα-helixtrans-81.8-15.4179.9-62.6-176.4000113.6D388 L392 Q444 K449D388-L447 HydrophobicContact CB-CD1 3.56Å; L392-L447 HydrophobicContact CD1-CD1 4.17Å; L392-L447 HydrophobicContact CD2-CD1 3.43Å; L392-L447 VanDerWaalsContact CD2-CD1 3.43Å; L392-L447 HydrophobicContact CD2-CD2 4.14Å; L392-L447 HydrophobicContact CD2-CG 3.68Å; L392-L447 HydrophobicContact CG-CD1 3.59Å; L392-L447 HydrophobicContact CG-CG 4.39Å; Q444-L447 PolarHBondContact O-N 3.47Å; L447-K449 PolarHBondContact O-N 2.94Å
448D72.1Confident69Low49 Ų4968 Ų6826%0.26235%0.347SS..  trans-54.8122.5178.2-81.4-15.1000111.5Q444 S450 N455 R459Q444-D448 PolarHBondContact O-N 2.92Å; D448-S450 VanDerWaalsContact C-N 3.29Å; D448-S450 PolarHBondContact O-N 3.37Å; D448-N455 PolarHBondContact OD2-ND2 3.02Å; D448-R459 PolarHBondContact O-NH1 3.07Å; D448-R459 PolarHBondContact O-NH2 3.3Å
449K69.9Low70.3Confident212 Ų21269.6 Ų69.692%0.92235%0.352SS*.SBendtrans-68.8-26.3-176.7-65.5-177.6-177.5176.40113.2L447L447-K449 PolarHBondContact O-N 2.94Å
450S75Confident71.8Confident74 Ų7469.2 Ų69.252%0.51735%0.349SS..SBendtrans-128.4145.7-17855.10000112.7D448 N455 R459D448-S450 VanDerWaalsContact C-N 3.29Å; D448-S450 PolarHBondContact O-N 3.37Å; S450-N455 PolarHBondContact O-ND2 3.15Å; S450-R459 VanDerWaalsContact C-NH1 3.32Å; S450-R459 PolarHBondContact O-NH1 2.93Å
451L81.8Confident72.9Confident97 Ų9770 Ų7051%0.50835%0.353SS..  trans-79.7128169.1-73.8165000108.9Y456 R459 L460L451-Y456 HydrophobicContact CD2-CD2 4.03Å; L451-R459 HydrophobicContact CD2-CB 4.32Å; L451-R459 HydrophobicContact CD2-CG 4.17Å; L451-L460 HydrophobicContact CD2-CD2 3.88Å
452T77.6Confident73.8Confident58 Ų5870 Ų7036%0.35635%0.352SS..  trans-124161.2176.566.50000109.3S454 N455 Y456T452-S454 PolarHBondContact O-N 2.83Å; T452-S454 VanDerWaalsContact O-N 3.16Å; T452-S454 PolarHBondContact OG1-OG 3.35Å; T452-N455 PolarHBondContact N-OD1 2.97Å; T452-N455 PolarHBondContact O-N 3.17Å; T452-N455 PolarHBondContact O-OD1 3.45Å; T452-N455 VanDerWaalsContact O-OD1 3.12Å; T452-N455 PolarHBondContact OG1-N 2.99Å; T452-N455 PolarHBondContact OG1-ND2 3.47Å; T452-N455 PolarHBondContact OG1-OD1 3.47Å; T452-N455 VanDerWaalsContact OG1-OD1 3.08Å; T452-Y456 WeakPolarHBondContact O-CB 3.45Å; T452-Y456 PolarHBondContact O-N 2.91Å
453K78.2Confident74.8Confident216 Ų21672.1 Ų72.194%0.93937%0.365SS*.THydrogen-bonded Turntrans-56.7-32.3178.6-173179.3177.6-176.80112.5
454S72.5Confident75.6Confident114 Ų11475.7 Ų75.780%0.79738%0.384SS*.THydrogen-bonded Turntrans-84.6-28.1-177.9500000114.2T452T452-S454 PolarHBondContact O-N 2.83Å; T452-S454 VanDerWaalsContact O-N 3.16Å; T452-S454 PolarHBondContact OG1-OG 3.35Å
455N75.9Confident76.3Confident20 Ų2076.6 Ų76.611%0.10739%0.387CS..THydrogen-bonded Turntrans-101.3-11-179.675.55.5000114.3D448 S450 T452 Q457 S458 R459D448-N455 PolarHBondContact OD2-ND2 3.02Å; S450-N455 PolarHBondContact O-ND2 3.15Å; T452-N455 PolarHBondContact N-OD1 2.97Å; T452-N455 PolarHBondContact O-N 3.17Å; T452-N455 PolarHBondContact O-OD1 3.45Å; T452-N455 VanDerWaalsContact O-OD1 3.12Å; T452-N455 PolarHBondContact OG1-N 2.99Å; T452-N455 PolarHBondContact OG1-ND2 3.47Å; T452-N455 PolarHBondContact OG1-OD1 3.47Å; T452-N455 VanDerWaalsContact OG1-OD1 3.08Å; N455-Q457 PolarHBondContact O-N 3.39Å; N455-S458 PolarHBondContact O-N 3.23Å; N455-R459 VanDerWaalsContact O-CB 3.26Å; N455-R459 WeakPolarHBondContact O-CB 3.13Å; N455-R459 PolarHBondContact O-N 3.41Å
456Y80.7Confident76.8Confident134 Ų13478.2 Ų78.253%0.52540%0.395SS..Hα-helixtrans-52.9-53.7-173.8178.2-94000112.5L451 T452 R459 L460L451-Y456 HydrophobicContact CD2-CD2 4.03Å; T452-Y456 WeakPolarHBondContact O-CB 3.45Å; T452-Y456 PolarHBondContact O-N 2.91Å; Y456-R459 PolarHBondContact O-N 3.47Å; Y456-L460 HydrophobicContact CD2-CD2 3.82Å; Y456-L460 HydrophobicContact CE1-CD2 4.48Å; Y456-L460 HydrophobicContact CE1-CG 4.32Å; Y456-L460 HydrophobicContact CE2-CD2 3.65Å; Y456-L460 HydrophobicContact CE2-CG 4.16Å; Y456-L460 HydrophobicContact CG-CD2 4.31Å; Y456-L460 WeakPolarHBondContact O-CB 3.47Å; Y456-L460 WeakPolarHBondContact O-CD2 3.48Å; Y456-L460 PolarHBondContact O-N 2.88Å
457Q78.4Confident77.6Confident143 Ų14382.4 Ų82.467%0.66841%0.412SS*.Hα-helixtrans-62.2-53.1-175.7-174.1178.51.200111.4N455 R459 L460 H461N455-Q457 PolarHBondContact O-N 3.39Å; Q457-R459 VanDerWaalsContact C-N 3.32Å; Q457-R459 PolarHBondContact O-N 3.33Å; Q457-L460 PolarHBondContact O-N 3.03Å; Q457-H461 PolarHBondContact O-CD2 3.18Å; Q457-H461 VanDerWaalsContact O-CD2 3.26Å; Q457-H461 PolarHBondContact O-N 3.04Å; Q457-H461 VanDerWaalsContact O-N 3.11Å
458S73.8Confident78.2Confident36 Ų3682.4 Ų82.425%0.25241%0.411SS..Hα-helixtrans-57.6-47.5179.9-169.10000111.1N455 L460 H461 D462N455-S458 PolarHBondContact O-N 3.23Å; S458-L460 PolarHBondContact O-N 2.7Å; S458-H461 PolarHBondContact O-N 3.28Å; S458-D462 PolarHBondContact O-N 2.78Å; S458-D462 PolarHBondContact OG-OD2 3Å
459R80Confident78.5Confident43 Ų4381.1 Ų81.116%0.16240%0.404CS..Hα-helixtrans-62.4-41.7-177.8-178.2169.1172.9179.213.2112.6S445 D448 S450 L451 N455 Y456 Q457 D462 L463S445-R459 VanDerWaalsContact O-CD 3.25Å; S445-R459 WeakPolarHBondContact O-CD 3.24Å; S445-R459 WeakPolarHBondContact O-CG 3.47Å; D448-R459 PolarHBondContact O-NH1 3.07Å; D448-R459 PolarHBondContact O-NH2 3.3Å; S450-R459 VanDerWaalsContact C-NH1 3.32Å; S450-R459 PolarHBondContact O-NH1 2.93Å; L451-R459 HydrophobicContact CD2-CB 4.32Å; L451-R459 HydrophobicContact CD2-CG 4.17Å; N455-R459 VanDerWaalsContact O-CB 3.26Å; N455-R459 WeakPolarHBondContact O-CB 3.13Å; N455-R459 PolarHBondContact O-N 3.41Å; Y456-R459 PolarHBondContact O-N 3.47Å; Q457-R459 VanDerWaalsContact C-N 3.32Å; Q457-R459 PolarHBondContact O-N 3.33Å; R459-D462 PolarHBondContact O-N 3.42Å; R459-L463 HydrophobicContact CG-CD1 4.08Å; R459-L463 HydrophobicContact CG-CG 4.35Å; R459-L463 WeakPolarHBondContact O-CB 3.33Å; R459-L463 VanDerWaalsContact O-CG 3.24Å; R459-L463 WeakPolarHBondContact O-CG 3.41Å; R459-L463 PolarHBondContact O-N 3.05Å
460L84.1Confident78.9Confident65 Ų6573.3 Ų73.334%0.3438%0.379SS..Hα-helixtrans-65.9-40.1178.3-92.6-67.6000111.9L451 Y456 Q457 S458 L464L451-L460 HydrophobicContact CD2-CD2 3.88Å; Y456-L460 HydrophobicContact CD2-CD2 3.82Å; Y456-L460 HydrophobicContact CE1-CD2 4.48Å; Y456-L460 HydrophobicContact CE1-CG 4.32Å; Y456-L460 HydrophobicContact CE2-CD2 3.65Å; Y456-L460 HydrophobicContact CE2-CG 4.16Å; Y456-L460 HydrophobicContact CG-CD2 4.31Å; Y456-L460 WeakPolarHBondContact O-CB 3.47Å; Y456-L460 WeakPolarHBondContact O-CD2 3.48Å; Y456-L460 PolarHBondContact O-N 2.88Å; Q457-L460 PolarHBondContact O-N 3.03Å; S458-L460 PolarHBondContact O-N 2.7Å; L460-L464 WeakPolarHBondContact O-CB 3.32Å; L460-L464 PolarHBondContact O-N 2.78Å
461H80.7Confident79.2Confident83 Ų8373 Ų7338%0.38437%0.369SS..Hα-helixtrans-62-45.4173.2-85.1-88.3000111.7Q457 S458 L463 L464 Y465Q457-H461 PolarHBondContact O-CD2 3.18Å; Q457-H461 VanDerWaalsContact O-CD2 3.26Å; Q457-H461 PolarHBondContact O-N 3.04Å; Q457-H461 VanDerWaalsContact O-N 3.11Å; S458-H461 PolarHBondContact O-N 3.28Å; H461-L463 PolarHBondContact O-N 2.98Å; H461-L464 PolarHBondContact O-N 2.65Å; H461-Y465 HydrophobicContact CB-CE2 4.18Å; H461-Y465 WeakPolarHBondContact O-CD2 3.4Å; H461-Y465 VanDerWaalsContact O-CG 3.29Å; H461-Y465 PolarHBondContact O-N 2.99Å
462D77.4Confident79.1Confident0 Ų070.5 Ų70.50%035%0.353CS..Hα-helixtrans-66-39.9-178.9-60.1-30.8000111.7R362 T443 S445 V446 S458 R459 L464 Y465 I466R362-D462 IonicContact CZ-OD1 2.68Å; R362-D462 VanDerWaalsContact CZ-OD1 3.27Å; R362-D462 IonicContact NH1-OD1 2.57Å; R362-D462 PolarHBondContact NH1-OD1 3Å; R362-D462 IonicContact NH2-OD1 2.72Å; R362-D462 PolarHBondContact NH2-OD1 3.34Å; T443-D462 PolarHBondContact OG1-OD2 3.49Å; T443-D462 VanDerWaalsContact OG1-OD2 3.05Å; S445-D462 PolarHBondContact OG-OD2 3.43Å; V446-D462 HydrophobicContact CG2-CB 3.6Å; S458-D462 PolarHBondContact O-N 2.78Å; S458-D462 PolarHBondContact OG-OD2 3Å; R459-D462 PolarHBondContact O-N 3.42Å; D462-L464 PolarHBondContact O-N 3.35Å; D462-Y465 PolarHBondContact O-N 3.48Å; D462-I466 VanDerWaalsContact O-CG1 3.26Å; D462-I466 WeakPolarHBondContact O-CG1 3.27Å; D462-I466 PolarHBondContact O-N 3.18Å
463L81.3Confident79.1Confident72 Ų7271 Ų7138%0.37735%0.35SS..Hα-helixtrans-62.7-40.7173.2-71.7174.6000112.4R459 H461 I466 E467R459-L463 HydrophobicContact CG-CD1 4.08Å; R459-L463 HydrophobicContact CG-CG 4.35Å; R459-L463 WeakPolarHBondContact O-CB 3.33Å; R459-L463 VanDerWaalsContact O-CG 3.24Å; R459-L463 WeakPolarHBondContact O-CG 3.41Å; R459-L463 PolarHBondContact O-N 3.05Å; H461-L463 PolarHBondContact O-N 2.98Å; L463-I466 PolarHBondContact O-N 3.36Å; L463-E467 PolarHBondContact O-N 3.13Å
464L83.9Confident79.3Confident76 Ų7663 Ų6340%0.39832%0.316SS..Hα-helixtrans-64.7-42.4177.1-175.3142.3000111.2Y432 L460 H461 D462 I466 E467 E468Y432-L464 HydrophobicContact CE2-CD2 4.32Å; Y432-L464 WeakPolarHBondContact OH-CD2 3.29Å; L460-L464 WeakPolarHBondContact O-CB 3.32Å; L460-L464 PolarHBondContact O-N 2.78Å; H461-L464 PolarHBondContact O-N 2.65Å; D462-L464 PolarHBondContact O-N 3.35Å; L464-I466 VanDerWaalsContact C-N 3.35Å; L464-I466 PolarHBondContact O-N 2.96Å; L464-E467 PolarHBondContact O-N 3.11Å; L464-E468 HydrophobicContact CD2-CG 4.39Å; L464-E468 WeakPolarHBondContact O-CG 3.32Å; L464-E468 PolarHBondContact O-N 2.92Å
465Y77.8Confident79.7Confident30 Ų3059.8 Ų59.812%0.11829%0.29CS..Hα-helixtrans-64.8-38.3175.3-60.5-46.9000112.9Y432 P435 L441 H461 D462 E467 E468 I469Y432-Y465 AromaticContact CE2-CE1 3.7Å; Y432-Y465 HydrophobicContact CE2-CE1 3.7Å; Y432-Y465 AromaticContact CZ-CE1 3.77Å; Y432-Y465 WeakPolarHBondContact OH-CD1 3.08Å; Y432-Y465 VanDerWaalsContact OH-CE1 3.31Å; Y432-Y465 WeakPolarHBondContact OH-CE1 3.38Å; P435-Y465 VanDerWaalsContact CD-CG 3.48Å; P435-Y465 HydrophobicContact CG-CD1 4.12Å; P435-Y465 HydrophobicContact CG-CD2 3.6Å; P435-Y465 HydrophobicContact CG-CE1 4.32Å; P435-Y465 HydrophobicContact CG-CE2 3.86Å; P435-Y465 HydrophobicContact CG-CG 3.76Å; L441-Y465 HydrophobicContact CD2-CD2 4.46Å; L441-Y465 HydrophobicContact CD2-CG 4.13Å; H461-Y465 HydrophobicContact CB-CE2 4.18Å; H461-Y465 WeakPolarHBondContact O-CD2 3.4Å; H461-Y465 VanDerWaalsContact O-CG 3.29Å; H461-Y465 PolarHBondContact O-N 2.99Å; D462-Y465 PolarHBondContact O-N 3.48Å; Y465-E467 VanDerWaalsContact C-N 3.34Å; Y465-E468 PolarHBondContact O-N 3.3Å; Y465-I469 PolarHBondContact O-N 2.76Å; Y465-I469 VanDerWaalsContact O-N 3.08Å
466I77.3Confident79.8Confident39 Ų3959.8 Ų59.820%0.229%0.291CS..Hα-helixtrans-61-45173.6-71.1164.6000110.4L441 F442 V446 D462 L463 L464 I469 A470L441-I466 HydrophobicContact CB-CG1 4.38Å; F442-I466 HydrophobicContact CD1-CD1 4.41Å; F442-I466 HydrophobicContact CE1-CD1 4.3Å; V446-I466 HydrophobicContact CB-CD1 4.37Å; V446-I466 HydrophobicContact CG1-CD1 3.68Å; V446-I466 HydrophobicContact CG2-CD1 3.73Å; D462-I466 VanDerWaalsContact O-CG1 3.26Å; D462-I466 WeakPolarHBondContact O-CG1 3.27Å; D462-I466 PolarHBondContact O-N 3.18Å; L463-I466 PolarHBondContact O-N 3.36Å; L464-I466 VanDerWaalsContact C-N 3.35Å; L464-I466 PolarHBondContact O-N 2.96Å; I466-I469 PolarHBondContact O-N 3.36Å; I466-A470 WeakPolarHBondContact O-CB 3.3Å; I466-A470 PolarHBondContact O-N 2.98Å
467E83.3Confident79.5Confident116 Ų11658.4 Ų58.454%0.54229%0.288SS..Hα-helixtrans-60.6-48.9177.4-176.1179.1176.100111.4L463 L464 Y465 I469 A470 Q471L463-E467 PolarHBondContact O-N 3.13Å; L464-E467 PolarHBondContact O-N 3.11Å; Y465-E467 VanDerWaalsContact C-N 3.34Å; E467-I469 PolarHBondContact O-N 3.33Å; E467-A470 WeakPolarHBondContact O-CB 3.36Å; E467-A470 PolarHBondContact O-N 3.41Å; E467-A470 VanDerWaalsContact O-N 3.16Å; E467-Q471 WeakPolarHBondContact O-CG 3.13Å; E467-Q471 PolarHBondContact O-N 3.08Å; E467-Q471 PolarHBondContact OE1-NE2 3.26Å
468E81Confident79.4Confident54 Ų5452.7 Ų52.725%0.25226%0.261SS..Hα-helixtrans-59.9-35.8179.4-74.9-174.1169.300112.7Y432 I434 L464 Y465 Q471 Y472Y432-E468 PolarHBondContact OH-OE1 2.96Å; Y432-E468 PolarHBondContact OH-OE2 3.2Å; I434-E468 WeakPolarHBondContact CD1-OE2 3.35Å; I434-E468 WeakPolarHBondContact CG1-OE2 3.41Å; L464-E468 HydrophobicContact CD2-CG 4.39Å; L464-E468 WeakPolarHBondContact O-CG 3.32Å; L464-E468 PolarHBondContact O-N 2.92Å; Y465-E468 PolarHBondContact O-N 3.3Å; E468-Q471 PolarHBondContact O-N 2.95Å; E468-Y472 WeakPolarHBondContact O-CB 3.45Å; E468-Y472 PolarHBondContact O-N 3.33Å
469I77.4Confident79.5Confident22 Ų2255.8 Ų55.811%0.11328%0.275CS..Hα-helixtrans-76.9-34.6177.8-75.5168.1000112.1L399 I434 L441 Y465 I466 E467 Q471 Y472 K473L399-I469 HydrophobicContact CD1-CG2 4.3Å; L399-I469 HydrophobicContact CD2-CG2 4.03Å; I434-I469 HydrophobicContact CG2-CD1 4.16Å; I434-I469 HydrophobicContact CG2-CG1 4.23Å; L441-I469 HydrophobicContact CD1-CD1 2.99Å; L441-I469 HydrophobicContact CD1-CG1 4.36Å; L441-I469 HydrophobicContact CD2-CD1 3.73Å; L441-I469 HydrophobicContact CG-CD1 3.96Å; Y465-I469 PolarHBondContact O-N 2.76Å; Y465-I469 VanDerWaalsContact O-N 3.08Å; I466-I469 PolarHBondContact O-N 3.36Å; E467-I469 PolarHBondContact O-N 3.33Å; I469-Q471 VanDerWaalsContact C-N 3.33Å; I469-Y472 PolarHBondContact O-N 3.26Å; I469-K473 WeakPolarHBondContact O-CB 3.32Å; I469-K473 PolarHBondContact O-N 3.17Å
470A79.1Confident79.4Confident48 Ų4856.4 Ų56.440%0.39728%0.281SS..Hα-helixtrans-61.1-45.1169.700000110.7I466 E467 Y472 K473 E474I466-A470 WeakPolarHBondContact O-CB 3.3Å; I466-A470 PolarHBondContact O-N 2.98Å; E467-A470 WeakPolarHBondContact O-CB 3.36Å; E467-A470 PolarHBondContact O-N 3.41Å; E467-A470 VanDerWaalsContact O-N 3.16Å; A470-Y472 PolarHBondContact O-N 3.46Å; A470-K473 PolarHBondContact O-N 3.03Å; A470-E474 PolarHBondContact O-N 3.26Å
471Q81.9Confident79.1Confident66 Ų6661.5 Ų61.531%0.30830%0.301SS..Hα-helixtrans-61.1-44.8174.1-68.1-175.628.700111.3E467 E468 I469 K473 E474 I475 L526E467-Q471 WeakPolarHBondContact O-CG 3.13Å; E467-Q471 PolarHBondContact O-N 3.08Å; E467-Q471 PolarHBondContact OE1-NE2 3.26Å; E468-Q471 PolarHBondContact O-N 2.95Å; I469-Q471 VanDerWaalsContact C-N 3.33Å; Q471-K473 PolarHBondContact O-N 3.39Å; Q471-E474 PolarHBondContact O-N 3.48Å; Q471-I475 VanDerWaalsContact O-CG1 3.31Å; Q471-I475 WeakPolarHBondContact O-CG1 3.44Å; Q471-I475 PolarHBondContact O-N 3.09Å; Q471-L526 HydrophobicContact CB-CD1 4.06Å; Q471-L526 HydrophobicContact CG-CD1 4.15Å; Q471-L526 HydrophobicContact CG-CD2 4.2Å
472Y79.3Confident78.9Confident45 Ų4561 Ų6118%0.17630%0.303CS..Hα-helixtrans-60-43.3175.8177.5-103.6000112.3T402 A403 R405 E468 I469 A470 E474 I475 S476T402-Y472 HydrophobicContact CG2-CD1 3.73Å; T402-Y472 HydrophobicContact CG2-CE1 3.7Å; A403-Y472 WeakPolarHBondContact O-CE1 3.33Å; A403-Y472 PolarHBondContact O-OH 3.4Å; R405-Y472 WeakPolarHBondContact CA-OH 3.4Å; R405-Y472 HydrophobicContact CB-CE1 4.1Å; R405-Y472 HydrophobicContact CB-CE2 4.03Å; R405-Y472 HydrophobicContact CG-CE2 3.91Å; R405-Y472 PolarHBondContact N-OH 2.9Å; E468-Y472 WeakPolarHBondContact O-CB 3.45Å; E468-Y472 PolarHBondContact O-N 3.33Å; I469-Y472 PolarHBondContact O-N 3.26Å; A470-Y472 PolarHBondContact O-N 3.46Å; Y472-E474 VanDerWaalsContact C-N 3.31Å; Y472-E474 PolarHBondContact O-N 3.47Å; Y472-I475 PolarHBondContact O-N 3.39Å; Y472-S476 VanDerWaalsContact O-CB 3.31Å; Y472-S476 WeakPolarHBondContact O-CB 3.42Å; Y472-S476 PolarHBondContact O-N 3.44Å
473K78.1Confident78.9Confident69 Ų6969.9 Ų69.930%0.334%0.344SS..Hα-helixtrans-59.6-43.1177.3-177.7175-179.7175.10111.3Q398 T402 I469 A470 Q471 S476Q398-K473 PolarHBondContact O-NZ 3.01Å; T402-K473 HydrophobicContact CG2-CB 3.86Å; T402-K473 HydrophobicContact CG2-CG 4.05Å; I469-K473 WeakPolarHBondContact O-CB 3.32Å; I469-K473 PolarHBondContact O-N 3.17Å; A470-K473 PolarHBondContact O-N 3.03Å; Q471-K473 PolarHBondContact O-N 3.39Å; K473-S476 PolarHBondContact O-N 3.47Å; K473-S476 PolarHBondContact O-OG 3.13Å
474E80.4Confident79.1Confident47 Ų4769.6 Ų69.622%0.2234%0.343CS..Hα-helixtrans-63.9-45174.6-70.2-58.1123.600112.1A470 Q471 Y472 S476 K477 A523 L526A470-E474 PolarHBondContact O-N 3.26Å; Q471-E474 PolarHBondContact O-N 3.48Å; Y472-E474 VanDerWaalsContact C-N 3.31Å; Y472-E474 PolarHBondContact O-N 3.47Å; E474-S476 VanDerWaalsContact C-N 3.32Å; E474-S476 PolarHBondContact O-N 2.89Å; E474-K477 WeakPolarHBondContact O-CB 3.22Å; E474-K477 WeakPolarHBondContact O-CG 3.36Å; E474-K477 PolarHBondContact O-N 2.93Å; E474-K477 IonicContact OE1-NZ 2.85Å; E474-K477 PolarHBondContact OE1-NZ 3.14Å; E474-K477 IonicContact OE2-NZ 2.58Å; E474-K477 PolarHBondContact OE2-NZ 2.96Å; E474-A523 HydrophobicContact CB-CB 4.07Å; E474-A523 WeakPolarHBondContact O-CB 3.4Å; E474-L526 HydrophobicContact CB-CD1 4.1Å
475I81.7Confident79.1Confident47 Ų4770.1 Ų70.124%0.24134%0.343CS..Hα-helixtrans-66-35178.2-65.4164.8000111.6Q471 Y472 K477 F478 L526 V531Q471-I475 VanDerWaalsContact O-CG1 3.31Å; Q471-I475 WeakPolarHBondContact O-CG1 3.44Å; Q471-I475 PolarHBondContact O-N 3.09Å; Y472-I475 PolarHBondContact O-N 3.39Å; I475-K477 PolarHBondContact O-N 3.42Å; I475-F478 PolarHBondContact O-N 3.42Å; I475-L526 HydrophobicContact CD1-CB 4.38Å; I475-L526 HydrophobicContact CG1-CB 4.14Å; I475-L526 HydrophobicContact CG1-CD1 4.29Å; I475-V531 HydrophobicContact CD1-CG2 4.04Å; I475-V531 HydrophobicContact CG1-CG2 4.45Å
476S77.9Confident79.6Confident21 Ų2173.3 Ų73.315%0.14736%0.361CS..Hα-helixtrans-61.3-19.3-177.2770000113.7Y472 K473 E474 F478 N479Y472-S476 VanDerWaalsContact O-CB 3.31Å; Y472-S476 WeakPolarHBondContact O-CB 3.42Å; Y472-S476 PolarHBondContact O-N 3.44Å; K473-S476 PolarHBondContact O-N 3.47Å; K473-S476 PolarHBondContact O-OG 3.13Å; E474-S476 VanDerWaalsContact C-N 3.32Å; E474-S476 PolarHBondContact O-N 2.89Å; S476-F478 PolarHBondContact O-N 3.24Å; S476-N479 VanDerWaalsContact O-CB 3.27Å; S476-N479 WeakPolarHBondContact O-CB 3.41Å; S476-N479 PolarHBondContact O-N 3.02Å; S476-N479 PolarHBondContact O-ND2 3.06Å
477K74.6Confident80.1Confident105 Ų10573.8 Ų73.846%0.45736%0.364SS..THydrogen-bonded Turntrans-61.9-23172.8-61.8176.2-174.2168.80112.6E474 I475E474-K477 WeakPolarHBondContact O-CB 3.22Å; E474-K477 WeakPolarHBondContact O-CG 3.36Å; E474-K477 PolarHBondContact O-N 2.93Å; E474-K477 IonicContact OE1-NZ 2.85Å; E474-K477 PolarHBondContact OE1-NZ 3.14Å; E474-K477 IonicContact OE2-NZ 2.58Å; E474-K477 PolarHBondContact OE2-NZ 2.96Å; I475-K477 PolarHBondContact O-N 3.42Å
478F75.4Confident80.3Confident22 Ų2271.4 Ų71.410%0.09637%0.365CS..THydrogen-bonded Turntrans-92.57176-61.3-77.1000113.7I475 S476 L480 L513 E515 L517 A523 V527I475-F478 PolarHBondContact O-N 3.42Å; S476-F478 PolarHBondContact O-N 3.24Å; F478-L480 WeakPolarHBondContact O-CD2 3.38Å; F478-L480 WeakPolarHBondContact O-CG 3.16Å; F478-L480 PolarHBondContact O-N 3.46Å; F478-L513 HydrophobicContact CD1-CD1 4.17Å; F478-L513 HydrophobicContact CE1-CD1 4.46Å; F478-E515 HydrophobicContact CE1-CB 4.27Å; F478-L517 HydrophobicContact CE1-CD2 4.09Å; F478-L517 HydrophobicContact CZ-CD2 4.03Å; F478-A523 HydrophobicContact CD2-CB 4.42Å; F478-A523 HydrophobicContact CE2-CB 3.49Å; F478-A523 VanDerWaalsContact CE2-CB 3.49Å; F478-A523 HydrophobicContact CZ-CB 4.13Å; F478-V527 HydrophobicContact CD2-CG2 3.57Å; F478-V527 HydrophobicContact CE2-CG2 3.67Å; F478-V527 HydrophobicContact CG-CG2 4.32Å
479N77.7Confident80.6Confident101 Ų10171.2 Ų71.254%0.5437%0.369SS..  trans-69.7125.2171.2-69.5-22.8000109.8S476S476-N479 VanDerWaalsContact O-CB 3.27Å; S476-N479 WeakPolarHBondContact O-CB 3.41Å; S476-N479 PolarHBondContact O-N 3.02Å; S476-N479 PolarHBondContact O-ND2 3.06Å
480L76.6Confident80.9Confident56 Ų5672 Ų7229%0.29337%0.372SS..  trans-148.8151.4-169.850.795.9000112.2F478 V482 F511 L513F478-L480 WeakPolarHBondContact O-CD2 3.38Å; F478-L480 WeakPolarHBondContact O-CG 3.16Å; F478-L480 PolarHBondContact O-N 3.46Å; L480-V482 HydrophobicContact CB-CG1 4.42Å; L480-V482 HydrophobicContact CD1-CB 3.88Å; L480-V482 HydrophobicContact CD1-CG1 3.31Å; L480-V482 HydrophobicContact CD1-CG2 3.32Å; L480-V482 HydrophobicContact CG-CG1 4.4Å; L480-F511 HydrophobicContact CD1-CD2 3.72Å; L480-F511 HydrophobicContact CD1-CE2 3.74Å; L480-F511 HydrophobicContact CD2-CE2 4.22Å; L480-F511 HydrophobicContact CG-CE2 4.49Å; L480-L513 HydrophobicContact CD2-CD2 3.34Å
481K78.1Confident80.9Confident173 Ų17375.2 Ų75.275%0.75238%0.38SS*.  trans-105.6110.5172.5-178.1179178.9178.40108.6
482V77.5Confident80.4Confident73 Ų7375.5 Ų75.544%0.44238%0.383SS..  trans-136.4164.2-175.4-68.50000112.8L480 F511L480-V482 HydrophobicContact CB-CG1 4.42Å; L480-V482 HydrophobicContact CD1-CB 3.88Å; L480-V482 HydrophobicContact CD1-CG1 3.31Å; L480-V482 HydrophobicContact CD1-CG2 3.32Å; L480-V482 HydrophobicContact CG-CG1 4.4Å; V482-F511 HydrophobicContact CG2-CB 3.82Å; V482-F511 HydrophobicContact CG2-CD2 3.94Å; V482-F511 HydrophobicContact CG2-CG 4.01Å
483Q77.4Confident79.7Confident185 Ų18576.3 Ų76.386%0.86439%0.393SS*.PPolyproline II helixtrans-87.9119.9166.4-65.5-177.8-0.600108.7
484L83.8Confident78.9Confident66 Ų6675.9 Ų75.935%0.34641%0.408SS..PPolyproline II helixtrans-81.1125.8177.9-165.667.3000109.5I486 F511 L536L484-I486 HydrophobicContact CB-CD1 4.49Å; L484-I486 HydrophobicContact CD2-CD1 3.79Å; L484-I486 HydrophobicContact CG-CD1 4Å; L484-F511 HydrophobicContact CD1-CB 4.11Å; L484-F511 HydrophobicContact CD1-CD1 3.56Å; L484-F511 HydrophobicContact CD1-CE1 4.42Å; L484-F511 HydrophobicContact CD1-CG 4.24Å; L484-L536 HydrophobicContact CD2-CD1 4.27Å
485Q84.2Confident77.6Confident87 Ų8781.2 Ų81.241%0.40744%0.443SS..EExtended strand (participates in β ladder)trans-83.3125.1170.6-67.4177.8-9.600108.6G509 R510Q485-G509 CarbonylContact O-C 3.56Å; Q485-G509 WeakPolarHBondContact O-CA 3.27Å; Q485-R510 HydrophobicContact CB-CB 4.35Å; Q485-R510 WeakPolarHBondContact CB-O 3.46Å; Q485-R510 PolarHBondContact N-O 3.01Å; Q485-R510 PolarHBondContact O-N 3.36Å; Q485-R510 VanDerWaalsContact OE1-NE 3.16Å
486I89.8Confident76.2Confident97 Ų9783.9 Ų83.950%0.49747%0.467SS..EExtended strand (participates in β ladder)trans-96.7128.8-178.9-55.6-58.1000109.2L484 L507 F508L484-I486 HydrophobicContact CB-CD1 4.49Å; L484-I486 HydrophobicContact CD2-CD1 3.79Å; L484-I486 HydrophobicContact CG-CD1 4Å; I486-L507 HydrophobicContact CG2-CB 3.83Å; I486-L507 HydrophobicContact CG2-CD1 3.79Å; I486-L507 HydrophobicContact CG2-CD2 4.03Å; I486-L507 HydrophobicContact CG2-CG 4.09Å; I486-F508 CarbonylContact C-O 3.51Å; I486-F508 WeakPolarHBondContact CA-O 3.48Å
487L88.1Confident75.4Confident50 Ų5086.4 Ų86.426%0.26250%0.495SS..EExtended strand (participates in β ladder)trans-131.4142.7-173-59.8169.4000110.3F508 R510L487-F508 HydrophobicContact CB-CB 4.3Å; L487-F508 PolarHBondContact N-O 3.5Å; L487-F508 PolarHBondContact O-N 3.34Å; L487-R510 HydrophobicContact CD1-CB 3.72Å; L487-R510 HydrophobicContact CD1-CG 4.46Å
488A87.5Confident75.4Confident66 Ų6682.6 Ų82.655%0.54549%0.487SS..SBendtrans-85-19.717000000112.3A502A488-A502 WeakPolarHBondContact O-CB 3.34Å; A488-A502 PolarHBondContact O-N 3Å
489S85.4Confident75.7Confident49 Ų4983.4 Ų83.434%0.34350%0.497SS..EExtended strand (participates in β ladder)trans-157.7154.7179.858.90000111.7K500 Y501S489-K500 CarbonylContact C-O 3.54Å; S489-K500 WeakPolarHBondContact CA-O 3.49Å; S489-K500 WeakPolarHBondContact CB-O 3.44Å; S489-Y501 VanDerWaalsContact CB-CD1 3.47Å
490F83.6Confident75.9Confident39 Ų3982 Ų8217%0.17149%0.486CS..EExtended strand (participates in β ladder)trans-142.5159.9170.366-88.4000111.1L492 A499 K500 F508 E560 E561F490-L492 HydrophobicContact CE2-CD2 3.9Å; F490-L492 HydrophobicContact CE2-CG 4.41Å; F490-A499 WeakPolarHBondContact O-CA 3.43Å; F490-K500 HydrophobicContact CE1-CB 4.15Å; F490-K500 HydrophobicContact CE1-CD 4.36Å; F490-K500 HydrophobicContact CE1-CG 4.5Å; F490-K500 HydrophobicContact CE2-CB 4.36Å; F490-K500 HydrophobicContact CZ-CB 4.03Å; F490-K500 HydrophobicContact CZ-CD 4Å; F490-K500 HydrophobicContact CZ-CG 4.45Å; F490-K500 PolarHBondContact N-O 2.94Å; F490-K500 PolarHBondContact O-N 3.33Å; F490-F508 HydrophobicContact CD1-CB 4.24Å; F490-F508 HydrophobicContact CD1-CD1 4.22Å; F490-F508 AromaticContact CD1-CD2 3.55Å; F490-F508 HydrophobicContact CD1-CD2 3.55Å; F490-F508 AromaticContact CD1-CE2 3.85Å; F490-F508 HydrophobicContact CD1-CE2 3.85Å; F490-F508 AromaticContact CD1-CG 3.74Å; F490-F508 HydrophobicContact CD1-CG 3.74Å; F490-F508 HydrophobicContact CD1-CZ 4.35Å; F490-F508 HydrophobicContact CE1-CB 4.48Å; F490-F508 AromaticContact CE1-CD1 3.69Å; F490-F508 HydrophobicContact CE1-CD1 3.69Å; F490-F508 AromaticContact CE1-CD2 3.75Å; F490-F508 HydrophobicContact CE1-CD2 3.75Å; F490-F508 AromaticContact CE1-CE1 3.74Å; F490-F508 HydrophobicContact CE1-CE1 3.74Å; F490-F508 AromaticContact CE1-CE2 3.75Å; F490-F508 HydrophobicContact CE1-CE2 3.75Å; F490-F508 AromaticContact CE1-CG 3.71Å; F490-F508 HydrophobicContact CE1-CG 3.71Å; F490-F508 AromaticContact CE1-CZ 3.77Å; F490-F508 HydrophobicContact CE1-CZ 3.77Å; F490-E560 HydrophobicContact CE1-CB 4.47Å; F490-E560 HydrophobicContact CZ-CB 4.09Å; F490-E561 WeakPolarHBondContact CD2-OE2 3.07Å; F490-E561 HydrophobicContact CE2-CB 4.06Å; F490-E561 WeakPolarHBondContact CE2-OE2 2.96Å; F490-E561 HydrophobicContact CZ-CB 4.44Å
491M79.2Confident76.4Confident115 Ų11586.6 Ų86.657%0.56750%0.501SS*.EExtended strand (participates in β ladder)trans-88.5130.6177.1-66.1-61.8-61.400109.6A499M491-A499 HydrophobicContact SD-CB 3.64Å
492L73.1Confident76.7Confident73 Ų7379.6 Ų79.638%0.38248%0.475SS..EExtended strand (participates in β ladder)trans-74.5133.5175.2-70.7160000109.9F490 G498F490-L492 HydrophobicContact CE2-CD2 3.9Å; F490-L492 HydrophobicContact CE2-CG 4.41Å; L492-G498 PolarHBondContact N-O 3.31Å
493T63.6Low76.9Confident61 Ų6182.4 Ų82.437%0.37448%0.483SS..  trans-96106.2178.164.60000110.1E561 T563 I567T493-E561 WeakPolarHBondContact CB-OE1 3.43Å; T493-E561 PolarHBondContact N-OE1 3Å; T493-E561 PolarHBondContact OG1-OE1 2.81Å; T493-T563 HydrophobicContact CG2-CG2 4.27Å; T493-T563 WeakPolarHBondContact OG1-CG2 3.38Å; T493-I567 HydrophobicContact CG2-CB 4.45Å; T493-I567 HydrophobicContact CG2-CD1 3.71Å; T493-I567 HydrophobicContact CG2-CG1 4.19Å
494G62.3Low77Confident61 Ų6181.2 Ų81.263%0.62948%0.483SS*.SBendtrans169.9-176.5-177.800000115.1S496G494-S496 PolarHBondContact O-N 3.44Å
495V52.9Low76.8Confident158 Ų15881.8 Ų81.896%0.95851%0.505SS*.SBendtrans-66.5-18.2-176.3-162.20000112.6
496S51.6Low76.9Confident104 Ų10481.5 Ų81.573%0.72750%0.504SS*.SBendtrans-109.376.8178.8-42.90000109G494 G498G494-S496 PolarHBondContact O-N 3.44Å; S496-G498 PolarHBondContact O-N 3.44Å
497G61Low76.8Confident73 Ų7382.5 Ų82.575%0.75351%0.509SS*.  trans-52.2128.7179.200000111.8
498G75.4Confident76.8Confident26 Ų2681.3 Ų81.327%0.26850%0.502SS..EExtended strand (participates in β ladder)trans-169.2162-17800000112.5L492 S496L492-G498 PolarHBondContact N-O 3.31Å; S496-G498 PolarHBondContact O-N 3.44Å
499A80.4Confident76.9Confident39 Ų3980.1 Ų80.132%0.32250%0.496SS..EExtended strand (participates in β ladder)trans-112.5131.9173.700000109.4F490 M491 Y501F490-A499 WeakPolarHBondContact O-CA 3.43Å; M491-A499 HydrophobicContact SD-CB 3.64Å; A499-Y501 HydrophobicContact CB-CD2 4.46Å; A499-Y501 HydrophobicContact CB-CE2 3.68Å
500K83.2Confident76.8Confident70 Ų7081.1 Ų81.130%0.30449%0.493SS..EExtended strand (participates in β ladder)trans-98.2130.3173.4-165.3167.9176.3170.20109S489 F490 F508 E560S489-K500 CarbonylContact C-O 3.54Å; S489-K500 WeakPolarHBondContact CA-O 3.49Å; S489-K500 WeakPolarHBondContact CB-O 3.44Å; F490-K500 HydrophobicContact CE1-CB 4.15Å; F490-K500 HydrophobicContact CE1-CD 4.36Å; F490-K500 HydrophobicContact CE1-CG 4.5Å; F490-K500 HydrophobicContact CE2-CB 4.36Å; F490-K500 HydrophobicContact CZ-CB 4.03Å; F490-K500 HydrophobicContact CZ-CD 4Å; F490-K500 HydrophobicContact CZ-CG 4.45Å; F490-K500 PolarHBondContact N-O 2.94Å; F490-K500 PolarHBondContact O-N 3.33Å; K500-F508 HydrophobicContact CD-CZ 4.28Å; K500-F508 HydrophobicContact CG-CE2 4.49Å; K500-F508 HydrophobicContact CG-CZ 3.98Å; K500-E560 IonicContact NZ-OE1 2.69Å; K500-E560 PolarHBondContact NZ-OE1 3.1Å; K500-E560 IonicContact NZ-OE2 3.43Å; K500-E560 PolarHBondContact NZ-OE2 3.21Å
501Y85.5Confident76.8Confident154 Ų15482.9 Ų82.960%0.60450%0.5SS*.EExtended strand (participates in β ladder)trans-112.8135.5179.6-64.7-92.5000109.5S489 A499S489-Y501 VanDerWaalsContact CB-CD1 3.47Å; A499-Y501 HydrophobicContact CB-CD2 4.46Å; A499-Y501 HydrophobicContact CB-CE2 3.68Å
502A84.7Confident76.5Confident26 Ų2684.6 Ų84.622%0.21551%0.505CS..  trans-70.2139.5175.700000109.3A488 Q506 F508A488-A502 WeakPolarHBondContact O-CB 3.34Å; A488-A502 PolarHBondContact O-N 3Å; A502-Q506 HydrophobicContact CB-CB 4.42Å; A502-Q506 WeakPolarHBondContact CB-O 3.36Å; A502-F508 HydrophobicContact CB-CD2 3.96Å; A502-F508 HydrophobicContact CB-CE2 3.66Å; A502-F508 HydrophobicContact CB-CZ 4.08Å; A502-F508 VanDerWaalsContact N-CE2 3.27Å
503Q82.4Confident76.3Confident131 Ų13183.1 Ų83.161%0.61250%0.497SS*.  trans-119.1159.5-176.4-60.8-172.76.800110.6G505 Q506Q503-G505 VanDerWaalsContact C-N 3.31Å; Q503-G505 PolarHBondContact O-N 2.86Å; Q503-G505 VanDerWaalsContact O-N 3.17Å; Q503-Q506 VanDerWaalsContact O-CB 3.22Å; Q503-Q506 WeakPolarHBondContact O-CB 3.3Å; Q503-Q506 VanDerWaalsContact O-CG 3.29Å; Q503-Q506 WeakPolarHBondContact O-CG 3.37Å; Q503-Q506 PolarHBondContact O-N 3.34Å; Q503-Q506 PolarHBondContact O-OE1 3.02Å
504N79.6Confident76.2Confident160 Ų16086 Ų8686%0.85652%0.515SS*.THydrogen-bonded Turntrans54.239.3169.5-57.2-24.7000115.2Q506N504-Q506 VanDerWaalsContact C-N 3.26Å; N504-Q506 PolarHBondContact O-N 2.75Å
505G80.2Confident76.2Confident79 Ų7988.5 Ų88.581%0.81451%0.51SS*.THydrogen-bonded Turntrans78.44.117900000115Q503Q503-G505 VanDerWaalsContact C-N 3.31Å; Q503-G505 PolarHBondContact O-N 2.86Å; Q503-G505 VanDerWaalsContact O-N 3.17Å
506Q85.4Confident76.8Confident81 Ų8187 Ų8738%0.37950%0.501SS..  trans-70.8159.4171.1-62.9175.9-30.400111.3A502 Q503 N504A502-Q506 HydrophobicContact CB-CB 4.42Å; A502-Q506 WeakPolarHBondContact CB-O 3.36Å; Q503-Q506 VanDerWaalsContact O-CB 3.22Å; Q503-Q506 WeakPolarHBondContact O-CB 3.3Å; Q503-Q506 VanDerWaalsContact O-CG 3.29Å; Q503-Q506 WeakPolarHBondContact O-CG 3.37Å; Q503-Q506 PolarHBondContact O-N 3.34Å; Q503-Q506 PolarHBondContact O-OE1 3.02Å; N504-Q506 VanDerWaalsContact C-N 3.26Å; N504-Q506 PolarHBondContact O-N 2.75Å
507L88.2Confident77.7Confident117 Ų11782.8 Ų82.861%0.61347%0.471SS*.  trans-140.5144.2177.8-70.9167.1000109.2I486I486-L507 HydrophobicContact CG2-CB 3.83Å; I486-L507 HydrophobicContact CG2-CD1 3.79Å; I486-L507 HydrophobicContact CG2-CD2 4.03Å; I486-L507 HydrophobicContact CG2-CG 4.09Å
508F88.3Confident78.3Confident26 Ų2680.5 Ų80.511%0.11444%0.443CS..EExtended strand (participates in β ladder)trans-88.2138.1173.1-60.9-61.2000110.5I486 L487 F490 K500 A502 E560I486-F508 CarbonylContact C-O 3.51Å; I486-F508 WeakPolarHBondContact CA-O 3.48Å; L487-F508 HydrophobicContact CB-CB 4.3Å; L487-F508 PolarHBondContact N-O 3.5Å; L487-F508 PolarHBondContact O-N 3.34Å; F490-F508 HydrophobicContact CD1-CB 4.24Å; F490-F508 HydrophobicContact CD1-CD1 4.22Å; F490-F508 AromaticContact CD1-CD2 3.55Å; F490-F508 HydrophobicContact CD1-CD2 3.55Å; F490-F508 AromaticContact CD1-CE2 3.85Å; F490-F508 HydrophobicContact CD1-CE2 3.85Å; F490-F508 AromaticContact CD1-CG 3.74Å; F490-F508 HydrophobicContact CD1-CG 3.74Å; F490-F508 HydrophobicContact CD1-CZ 4.35Å; F490-F508 HydrophobicContact CE1-CB 4.48Å; F490-F508 AromaticContact CE1-CD1 3.69Å; F490-F508 HydrophobicContact CE1-CD1 3.69Å; F490-F508 AromaticContact CE1-CD2 3.75Å; F490-F508 HydrophobicContact CE1-CD2 3.75Å; F490-F508 AromaticContact CE1-CE1 3.74Å; F490-F508 HydrophobicContact CE1-CE1 3.74Å; F490-F508 AromaticContact CE1-CE2 3.75Å; F490-F508 HydrophobicContact CE1-CE2 3.75Å; F490-F508 AromaticContact CE1-CG 3.71Å; F490-F508 HydrophobicContact CE1-CG 3.71Å; F490-F508 AromaticContact CE1-CZ 3.77Å; F490-F508 HydrophobicContact CE1-CZ 3.77Å; K500-F508 HydrophobicContact CD-CZ 4.28Å; K500-F508 HydrophobicContact CG-CE2 4.49Å; K500-F508 HydrophobicContact CG-CZ 3.98Å; A502-F508 HydrophobicContact CB-CD2 3.96Å; A502-F508 HydrophobicContact CB-CE2 3.66Å; A502-F508 HydrophobicContact CB-CZ 4.08Å; A502-F508 VanDerWaalsContact N-CE2 3.27Å; F508-E560 HydrophobicContact CD1-CG 4.38Å; F508-E560 HydrophobicContact CE1-CG 4.05Å
509G88.1Confident78.4Confident41 Ų4184 Ų8442%0.42345%0.452SS..EExtended strand (participates in β ladder)trans-104.9121.4170.100000110.5Q485Q485-G509 CarbonylContact O-C 3.56Å; Q485-G509 WeakPolarHBondContact O-CA 3.27Å
510R84.7Confident78.2Confident69 Ų6989 Ų8926%0.2647%0.473SS..EExtended strand (participates in β ladder)trans-111.8135.1175.5-169.6179.682.8162.73.9110.7Q485 L487 Y566 I567Q485-R510 HydrophobicContact CB-CB 4.35Å; Q485-R510 WeakPolarHBondContact CB-O 3.46Å; Q485-R510 PolarHBondContact N-O 3.01Å; Q485-R510 PolarHBondContact O-N 3.36Å; Q485-R510 VanDerWaalsContact OE1-NE 3.16Å; L487-R510 HydrophobicContact CD1-CB 3.72Å; L487-R510 HydrophobicContact CD1-CG 4.46Å; R510-Y566 PolarHBondContact NH2-OH 3.08Å; R510-Y566 VanDerWaalsContact NH2-OH 3.11Å; R510-I567 PolarHBondContact NH1-O 3.13Å; R510-I567 PolarHBondContact NH1-OXT 2.91Å
511F83.3Confident78.1Confident76 Ų7688.6 Ų88.633%0.33348%0.477SS..  trans-148.2161.217264.1-79.7000110.6L480 V482 L484 L513L480-F511 HydrophobicContact CD1-CD2 3.72Å; L480-F511 HydrophobicContact CD1-CE2 3.74Å; L480-F511 HydrophobicContact CD2-CE2 4.22Å; L480-F511 HydrophobicContact CG-CE2 4.49Å; V482-F511 HydrophobicContact CG2-CB 3.82Å; V482-F511 HydrophobicContact CG2-CD2 3.94Å; V482-F511 HydrophobicContact CG2-CG 4.01Å; L484-F511 HydrophobicContact CD1-CB 4.11Å; L484-F511 HydrophobicContact CD1-CD1 3.56Å; L484-F511 HydrophobicContact CD1-CE1 4.42Å; L484-F511 HydrophobicContact CD1-CG 4.24Å; F511-L513 HydrophobicContact CD2-CD2 4.26Å; F511-L513 HydrophobicContact CE2-CD2 3.59Å; F511-L513 HydrophobicContact CZ-CD2 4.48Å
512K71.8Confident77.9Confident152 Ų15287.2 Ų87.266%0.66148%0.48SS*.  trans-102.4133.1178.2-173.2177177.7178.40109.6Y566K512-Y566 HydrophobicContact CD-CD2 4.37Å
513L68.8Low77.5Confident41 Ų4186.3 Ų86.322%0.21547%0.472CS..  trans-74.2146.7170.5-60.7177.7000110.3F478 L480 F511 E515 L517F478-L513 HydrophobicContact CD1-CD1 4.17Å; F478-L513 HydrophobicContact CE1-CD1 4.46Å; L480-L513 HydrophobicContact CD2-CD2 3.34Å; F511-L513 HydrophobicContact CD2-CD2 4.26Å; F511-L513 HydrophobicContact CE2-CD2 3.59Å; F511-L513 HydrophobicContact CZ-CD2 4.48Å; L513-E515 VanDerWaalsContact C-N 3.31Å; L513-E515 WeakPolarHBondContact CB-O 3.44Å; L513-L517 HydrophobicContact CD1-CD1 3.36Å; L513-L517 HydrophobicContact CD1-CD2 3.97Å; L513-L517 HydrophobicContact CD1-CG 3.48Å; L513-L517 VanDerWaalsContact CD1-CG 3.48Å
514T62.7Low77.5Confident122 Ų12280.1 Ų80.175%0.74844%0.443SS*.SBendtrans-67.9-33.217530.30000112.3
515E63Low77.8Confident113 Ų11378.9 Ų78.953%0.52843%0.427SS..SBendtrans-108.5145.2177.1-64.7-173.5175.700110.9F478 L513 L517F478-E515 HydrophobicContact CE1-CB 4.27Å; L513-E515 VanDerWaalsContact C-N 3.31Å; L513-E515 WeakPolarHBondContact CB-O 3.44Å; E515-L517 PolarHBondContact O-N 3.36Å
516T64.1Low78.1Confident126 Ų12676.6 Ų76.677%0.77340%0.395SS*.  trans-70.8124.2176.548.30000110.4S518T516-S518 PolarHBondContact O-N 3.39Å; T516-S518 VanDerWaalsContact O-N 3.13Å
517L70.6Confident78Confident17 Ų1773.5 Ų73.59%0.08938%0.382CS..  trans-64.6111.4171.3-76.5163.9000110F478 L513 E515 V527 M528 K564F478-L517 HydrophobicContact CE1-CD2 4.09Å; F478-L517 HydrophobicContact CZ-CD2 4.03Å; L513-L517 HydrophobicContact CD1-CD1 3.36Å; L513-L517 HydrophobicContact CD1-CD2 3.97Å; L513-L517 HydrophobicContact CD1-CG 3.48Å; L513-L517 VanDerWaalsContact CD1-CG 3.48Å; E515-L517 PolarHBondContact O-N 3.36Å; L517-V527 HydrophobicContact CD1-CG1 4.46Å; L517-V527 HydrophobicContact CD2-CB 3.74Å; L517-V527 HydrophobicContact CD2-CG1 3.57Å; L517-V527 HydrophobicContact CD2-CG2 4.44Å; L517-M528 HydrophobicContact CB-SD 4.2Å; L517-M528 HydrophobicContact CD1-SD 4Å; L517-K564 VanDerWaalsContact O-CE 3.27Å; L517-K564 WeakPolarHBondContact O-CE 3.47Å; L517-K564 WeakPolarHBondContact O-CG 3.26Å
518S73.1Confident77.8Confident25 Ų2569.9 Ų69.918%0.17536%0.363CS..  trans-121.5133.4169.8-175.50000111.1T516 D520 T521 G524T516-S518 PolarHBondContact O-N 3.39Å; T516-S518 VanDerWaalsContact O-N 3.13Å; S518-D520 PolarHBondContact O-N 3.34Å; S518-D520 WeakPolarHBondContact OG-CB 3.37Å; S518-D520 PolarHBondContact OG-N 2.77Å; S518-D520 PolarHBondContact OG-OD2 3.4Å; S518-T521 PolarHBondContact O-N 3.35Å; S518-T521 VanDerWaalsContact O-N 3.1Å; S518-T521 PolarHBondContact O-OG1 3.47Å; S518-G524 CarbonylContact O-C 3.59Å; S518-G524 WeakPolarHBondContact O-CA 3.5Å
519E77.4Confident77.6Confident99 Ų9972.3 Ų72.346%0.46338%0.38SS..THydrogen-bonded Turntrans-65.8-13.8173.2-63.7-174.3164.300113.1T521 R525 M528E519-T521 VanDerWaalsContact C-N 3.3Å; E519-R525 PolarHBondContact O-NE 3.18Å; E519-R525 VanDerWaalsContact O-NE 3.1Å; E519-R525 PolarHBondContact O-NH2 3.01Å; E519-M528 HydrophobicContact CG-CG 4.42Å
520D77.9Confident77.5Confident143 Ų14377.7 Ų77.777%0.76539%0.391SS*.THydrogen-bonded Turntrans-77.9-18.4175-55.8-42.1000112.2S518S518-D520 PolarHBondContact O-N 3.34Å; S518-D520 WeakPolarHBondContact OG-CB 3.37Å; S518-D520 PolarHBondContact OG-N 2.77Å; S518-D520 PolarHBondContact OG-OD2 3.4Å
521T81.1Confident77.6Confident63 Ų6375.7 Ų75.739%0.38739%0.387SS..SBendtrans-94.2144.4175.366.40000110.4S518 E519 A523 G524 R525S518-T521 PolarHBondContact O-N 3.35Å; S518-T521 VanDerWaalsContact O-N 3.1Å; S518-T521 PolarHBondContact O-OG1 3.47Å; E519-T521 VanDerWaalsContact C-N 3.3Å; T521-A523 VanDerWaalsContact C-N 3.34Å; T521-A523 PolarHBondContact O-N 2.9Å; T521-G524 PolarHBondContact O-N 3.32Å; T521-G524 WeakPolarHBondContact OG1-CA 3.31Å; T521-G524 PolarHBondContact OG1-N 3.08Å; T521-R525 WeakPolarHBondContact O-CB 3.33Å; T521-R525 PolarHBondContact O-N 3.43Å
522L80.1Confident77.8Confident125 Ų12577.5 Ų77.565%0.65440%0.4SS*.Hα-helixtrans-56.1-49.9176.8-67.4174.7000111.2R525 L526L522-R525 PolarHBondContact O-N 3.31Å; L522-L526 WeakPolarHBondContact O-CG 3.4Å; L522-L526 PolarHBondContact O-N 3.48Å; L522-L526 VanDerWaalsContact O-N 3.11Å
523A77.7Confident78.7Confident7 Ų771.8 Ų71.86%0.05838%0.381CS..Hα-helixtrans-64.5-44.8-179.700000112.1E474 F478 T521 L526 V527E474-A523 HydrophobicContact CB-CB 4.07Å; E474-A523 WeakPolarHBondContact O-CB 3.4Å; F478-A523 HydrophobicContact CD2-CB 4.42Å; F478-A523 HydrophobicContact CE2-CB 3.49Å; F478-A523 VanDerWaalsContact CE2-CB 3.49Å; F478-A523 HydrophobicContact CZ-CB 4.13Å; T521-A523 VanDerWaalsContact C-N 3.34Å; T521-A523 PolarHBondContact O-N 2.9Å; A523-L526 PolarHBondContact O-N 3.29Å; A523-V527 WeakPolarHBondContact O-CG2 3.44Å; A523-V527 PolarHBondContact O-N 2.73Å
524G81.6Confident79.6Confident0 Ų071.9 Ų71.90%038%0.383CS..Hα-helixtrans-66.6-38.7178.500000113S518 T521 V527 M528S518-G524 CarbonylContact O-C 3.59Å; S518-G524 WeakPolarHBondContact O-CA 3.5Å; T521-G524 PolarHBondContact O-N 3.32Å; T521-G524 WeakPolarHBondContact OG1-CA 3.31Å; T521-G524 PolarHBondContact OG1-N 3.08Å; G524-V527 PolarHBondContact O-N 3.14Å; G524-M528 WeakPolarHBondContact O-CB 3.23Å; G524-M528 WeakPolarHBondContact O-CG 3.29Å; G524-M528 PolarHBondContact O-N 3.11Å
525R85.4Confident80.9Confident135 Ų13570.8 Ų70.851%0.50937%0.366SS..Hα-helixtrans-60.5-45.9173.3-173.2179.9-61.3-178.80.4111.8E519 T521 L522 M528 T529E519-R525 PolarHBondContact O-NE 3.18Å; E519-R525 VanDerWaalsContact O-NE 3.1Å; E519-R525 PolarHBondContact O-NH2 3.01Å; T521-R525 WeakPolarHBondContact O-CB 3.33Å; T521-R525 PolarHBondContact O-N 3.43Å; L522-R525 PolarHBondContact O-N 3.31Å; R525-M528 PolarHBondContact O-N 3.13Å; R525-T529 HydrophobicContact CG-CG2 4.41Å; R525-T529 WeakPolarHBondContact O-CB 3.44Å; R525-T529 WeakPolarHBondContact O-CG2 3.31Å; R525-T529 PolarHBondContact O-N 2.99Å; R525-T529 PolarHBondContact O-OG1 3.46Å
526L86.1Confident82Confident30 Ų3068.1 Ų68.116%0.15736%0.355CS..Hα-helixtrans-60.1-48.4177.3-74.3170000111.2Q471 E474 I475 L522 A523 M528 T529 K530 V531Q471-L526 HydrophobicContact CB-CD1 4.06Å; Q471-L526 HydrophobicContact CG-CD1 4.15Å; Q471-L526 HydrophobicContact CG-CD2 4.2Å; E474-L526 HydrophobicContact CB-CD1 4.1Å; I475-L526 HydrophobicContact CD1-CB 4.38Å; I475-L526 HydrophobicContact CG1-CB 4.14Å; I475-L526 HydrophobicContact CG1-CD1 4.29Å; L522-L526 WeakPolarHBondContact O-CG 3.4Å; L522-L526 PolarHBondContact O-N 3.48Å; L522-L526 VanDerWaalsContact O-N 3.11Å; A523-L526 PolarHBondContact O-N 3.29Å; L526-M528 PolarHBondContact O-N 3.4Å; L526-T529 PolarHBondContact O-N 3.19Å; L526-K530 PolarHBondContact O-N 2.84Å; L526-V531 PolarHBondContact O-N 2.9Å
527V84.7Confident83.2Confident17 Ų1764.6 Ų64.610%0.10333%0.332CS..Hα-helixtrans-61.8-45.4178.6174.60000111.5F478 L517 A523 G524 V531 K562F478-V527 HydrophobicContact CD2-CG2 3.57Å; F478-V527 HydrophobicContact CE2-CG2 3.67Å; F478-V527 HydrophobicContact CG-CG2 4.32Å; L517-V527 HydrophobicContact CD1-CG1 4.46Å; L517-V527 HydrophobicContact CD2-CB 3.74Å; L517-V527 HydrophobicContact CD2-CG1 3.57Å; L517-V527 HydrophobicContact CD2-CG2 4.44Å; A523-V527 WeakPolarHBondContact O-CG2 3.44Å; A523-V527 PolarHBondContact O-N 2.73Å; G524-V527 PolarHBondContact O-N 3.14Å; V527-V531 HydrophobicContact CG2-CG2 4.32Å; V527-K562 WeakPolarHBondContact O-CD 3.26Å; V527-K562 WeakPolarHBondContact O-CE 3.37Å; V527-K562 PolarHBondContact O-NZ 2.67Å
528M82.4Confident83.9Confident41 Ų4167.9 Ų67.920%0.20235%0.354CS..Hα-helixtrans-66.7-41.4-178.2-69.1-63.1-70.100112.6L517 E519 G524 R525 L526 K562L517-M528 HydrophobicContact CB-SD 4.2Å; L517-M528 HydrophobicContact CD1-SD 4Å; E519-M528 HydrophobicContact CG-CG 4.42Å; G524-M528 WeakPolarHBondContact O-CB 3.23Å; G524-M528 WeakPolarHBondContact O-CG 3.29Å; G524-M528 PolarHBondContact O-N 3.11Å; R525-M528 PolarHBondContact O-N 3.13Å; L526-M528 PolarHBondContact O-N 3.4Å; M528-K562 HydrophobicContact CE-CB 4.09Å; M528-K562 PolarHBondContact O-NZ 3.32Å; M528-K562 HydrophobicContact SD-CB 3.63Å; M528-K562 HydrophobicContact SD-CD 4.11Å; M528-K562 HydrophobicContact SD-CG 4.5Å
529T84.2Confident84.1Confident77 Ų7770.9 Ų70.947%0.47237%0.371SS..Hα-helixtrans-98.3-27.9-16960.70000115.4R525 L526R525-T529 HydrophobicContact CG-CG2 4.41Å; R525-T529 WeakPolarHBondContact O-CB 3.44Å; R525-T529 WeakPolarHBondContact O-CG2 3.31Å; R525-T529 PolarHBondContact O-N 2.99Å; R525-T529 PolarHBondContact O-OG1 3.46Å; L526-T529 PolarHBondContact O-N 3.19Å
530K85.8Confident83.8Confident153 Ų15369.9 Ų69.967%0.66537%0.373SS*.Hα-helixtrans-123-23.8-169.1-60.9-59.7-178179.20115.1L526 N532L526-K530 PolarHBondContact O-N 2.84Å; K530-N532 PolarHBondContact O-N 3.26Å
531V87.3Confident83.1Confident27 Ų2773.6 Ų73.616%0.16438%0.382CS..  trans-85115.1-178.4-1790000110.1I475 L526 V527 A533 I559 K562I475-V531 HydrophobicContact CD1-CG2 4.04Å; I475-V531 HydrophobicContact CG1-CG2 4.45Å; L526-V531 PolarHBondContact O-N 2.9Å; V527-V531 HydrophobicContact CG2-CG2 4.32Å; V531-A533 WeakPolarHBondContact CG1-O 3.45Å; V531-I559 HydrophobicContact CG1-CD1 3.77Å; V531-K562 WeakPolarHBondContact O-CE 3.5Å; V531-K562 PolarHBondContact O-NZ 3.34Å
532N88.3Confident81.6Confident114 Ų11478.4 Ų78.461%0.6140%0.4SS*.  trans-111.1-11.1-176.5-62.2-20.7000113.8K530 I559K530-N532 PolarHBondContact O-N 3.26Å; N532-I559 PolarHBondContact O-N 2.89Å
533A89.4Confident80Confident32 Ų3282.5 Ų82.526%0.26441%0.413SS..EExtended strand (participates in β ladder)trans-143.6157.7-179.800000110.5V531 E556 A557V531-A533 WeakPolarHBondContact CG1-O 3.45Å; A533-E556 HydrophobicContact CB-CG 3.95Å; A533-A557 CarbonylContact C-O 3.53Å; A533-A557 VanDerWaalsContact CA-O 3.28Å; A533-A557 WeakPolarHBondContact CA-O 3.47Å
534V88.8Confident78.5Confident43 Ų4388.9 Ų88.926%0.26145%0.445SS..EExtended strand (participates in β ladder)trans-127.1149.2173.4-63.20000110.3L536 A557 I559V534-L536 HydrophobicContact CG2-CD2 4.15Å; V534-L536 HydrophobicContact CG2-CG 4.35Å; V534-A557 HydrophobicContact CG2-CB 4.11Å; V534-A557 PolarHBondContact N-O 2.65Å; V534-A557 PolarHBondContact O-N 3.36Å; V534-I559 HydrophobicContact CG1-CD1 3.72Å; V534-I559 HydrophobicContact CG1-CG1 3.95Å
535Y88.9Confident76.8Confident99 Ų9995.6 Ų95.639%0.38849%0.486SS..EExtended strand (participates in β ladder)trans-95.6133.2170.6-72.1-46.2000111.3W406 I413 V554 Y555 E556W406-Y535 HydrophobicContact CE3-CG 4.46Å; I413-Y535 HydrophobicContact CG2-CD1 4.27Å; I413-Y535 HydrophobicContact CG2-CE1 3.51Å; Y535-V554 HydrophobicContact CD1-CG1 3.99Å; Y535-V554 HydrophobicContact CG-CG1 3.91Å; Y535-Y555 CarbonylContact C-O 3.58Å; Y535-Y555 WeakPolarHBondContact CA-O 3.4Å; Y535-E556 HydrophobicContact CD1-CB 4.05Å; Y535-E556 HydrophobicContact CD1-CG 4.35Å; Y535-E556 HydrophobicContact CE1-CB 3.88Å; Y535-E556 HydrophobicContact CE1-CG 4.03Å
536L88.1Confident75Confident57 Ų5795.2 Ų95.230%0.29849%0.49SS..EExtended strand (participates in β ladder)trans-117.2125.6-177.9-59.6178.3000110.2L484 V534 V554 Y555 A557L484-L536 HydrophobicContact CD2-CD1 4.27Å; V534-L536 HydrophobicContact CG2-CD2 4.15Å; V534-L536 HydrophobicContact CG2-CG 4.35Å; L536-V554 WeakPolarHBondContact O-CA 3.37Å; L536-Y555 PolarHBondContact N-O 2.7Å; L536-Y555 PolarHBondContact O-N 3.27Å; L536-A557 HydrophobicContact CD1-CB 3.77Å; L536-A557 HydrophobicContact CG-CB 4.34Å
537L88.3Confident73Confident53 Ų5398.9 Ų98.928%0.27751%0.514SS..  trans-111112.2170.8179.162.8000109.2W406 V539 E552 K553 V554W406-L537 HydrophobicContact CH2-CB 3.42Å; W406-L537 VanDerWaalsContact CH2-CB 3.42Å; W406-L537 HydrophobicContact CH2-CD2 4.29Å; W406-L537 HydrophobicContact CZ2-CB 3.99Å; W406-L537 HydrophobicContact CZ2-CD2 3.98Å; W406-L537 HydrophobicContact CZ3-CB 4Å; L537-V539 PolarHBondContact O-N 3.41Å; L537-E552 HydrophobicContact CD1-CB 4.13Å; L537-K553 VanDerWaalsContact CD1-O 3.25Å; L537-K553 WeakPolarHBondContact CD1-O 3.39Å; L537-V554 HydrophobicContact CB-CG2 4.38Å; L537-V554 HydrophobicContact CD1-CG2 4.1Å
538P84.7Confident70.8Confident85 Ų85108 Ų10855%0.55256%0.555SS**  trans-63.8122.5175-2132.8000110.7P540 Y555P538-P540 VanDerWaalsContact O-CD 3.32Å; P538-P540 WeakPolarHBondContact O-CD 3.13Å; P538-Y555 HydrophobicContact CG-CD2 4.03Å; P538-Y555 HydrophobicContact CG-CE2 3.83Å
539V77.9Confident69.4Low88 Ų88109.9 Ų109.953%0.53359%0.586SS.*  trans-94.6108.6176-1760000108.9L537L537-V539 PolarHBondContact O-N 3.41Å
540P72Confident68.4Low79 Ų79110.7 Ų110.751%0.51359%0.591SS.*  trans-68.3144-179.427.7-33.5000111P538 Q542P538-P540 VanDerWaalsContact O-CD 3.32Å; P538-P540 WeakPolarHBondContact O-CD 3.13Å; P540-Q542 WeakPolarHBondContact CB-O 3.37Å; P540-Q542 PolarHBondContact O-N 2.78Å
541K62.1Low67.8Low221 Ų221108.4 Ų108.496%0.96158%0.581SS**SBendtrans-68.7-15.3178.6-66.5-175.6178.5176.90113.3
542Q50.8Low67.6Low163 Ų163110.5 Ų110.576%0.76259%0.588SS**SBendtrans-127.5137172.8-78.7173.4-12.700109.2P540 L544P540-Q542 WeakPolarHBondContact CB-O 3.37Å; P540-Q542 PolarHBondContact O-N 2.78Å; Q542-L544 PolarHBondContact O-N 2.92Å
543K46.2Very low67.5Low212 Ų212110.8 Ų110.892%0.92258%0.584SS**  trans-63.9103173.8-76-176.5176-178.50108.4V545K543-V545 PolarHBondContact O-N 3.46Å
544L46.1Very low67.5Low141 Ų141109.2 Ų109.274%0.73857%0.572SS**  trans-64.5132.7161.4-96.494.2000107.8Q542 Q546Q542-L544 PolarHBondContact O-N 2.92Å; L544-Q546 PolarHBondContact O-N 3.33Å
545V45.3Very low67.5Low140 Ų140111.8 Ų111.885%0.84858%0.577SS**  trans-58.2106.6166.2178.80000106.3K543 T547K543-V545 PolarHBondContact O-N 3.46Å; V545-T547 PolarHBondContact O-N 3.48Å; V545-T547 VanDerWaalsContact O-N 3.13Å
546Q48.1Very low67.5Low128 Ų128109.5 Ų109.560%0.59857%0.57SS**  trans-62.6116.2173-75.7178-5.600107.5L544 Q548 E552L544-Q546 PolarHBondContact O-N 3.33Å; Q546-Q548 PolarHBondContact O-N 2.99Å; Q546-E552 PolarHBondContact NE2-OE1 2.94Å
547T43.5Very low67.6Low107 Ų107108 Ų10866%0.65657%0.566SS**  trans-56.9123.7161.715.70000108V545 G549 T550V545-T547 PolarHBondContact O-N 3.48Å; V545-T547 VanDerWaalsContact O-N 3.13Å; T547-G549 PolarHBondContact O-N 3.46Å; T547-T550 PolarHBondContact O-OG1 3.09Å
548Q39Very low67.6Low207 Ų207108.4 Ų108.497%0.96757%0.571SS**THydrogen-bonded Turntrans-50.6115.4175.6-85.1175.2-35.400109.6Q546Q546-Q548 PolarHBondContact O-N 2.99Å
549G52.2Low67.8Low82 Ų82106.7 Ų106.785%0.84556%0.556SS**THydrogen-bonded Turntrans121.9-14.217100000117.1T547T547-G549 PolarHBondContact O-N 3.46Å
550T62.8Low68.2Low94 Ų94106.8 Ų106.858%0.57755%0.551SS**  trans-94.1115.5178.750.30000112.1T547T547-T550 PolarHBondContact O-OG1 3.09Å
551K74.6Confident68.7Low105 Ų105105.8 Ų105.846%0.45754%0.54SS..PPolyproline II helixtrans-60.7141.8170.7-69.7-179.4177.2179.30110.2S408 S409S408-K551 PolarHBondContact O-NZ 3.07Å; S409-K551 WeakPolarHBondContact O-CE 3.43Å; S409-K551 PolarHBondContact O-NZ 2.46Å
552E82.4Confident69.7Low70 Ų7097.8 Ų97.833%0.32751%0.505SS..PPolyproline II helixtrans-66139.1175.2-69.1-179.4153.800110.7K411 T412 L537 Q546K411-E552 HydrophobicContact CD-CB 3.89Å; K411-E552 IonicContact NZ-OE2 2.59Å; K411-E552 PolarHBondContact NZ-OE2 3.02Å; T412-E552 PolarHBondContact N-O 3.01Å; L537-E552 HydrophobicContact CD1-CB 4.13Å; Q546-E552 PolarHBondContact NE2-OE1 2.94Å
553K86.7Confident70.7Confident120 Ų12092.7 Ų92.752%0.52249%0.485SS..EExtended strand (participates in β ladder)trans-84127.7178.2-69.9179173-170.30110.6T412 I414 L537 Y555T412-K553 HydrophobicContact CG2-CG 4.49Å; T412-K553 WeakPolarHBondContact O-CA 3.25Å; I414-K553 HydrophobicContact CD1-CB 4.1Å; I414-K553 HydrophobicContact CD1-CD 3.93Å; I414-K553 HydrophobicContact CD1-CG 4.17Å; L537-K553 VanDerWaalsContact CD1-O 3.25Å; L537-K553 WeakPolarHBondContact CD1-O 3.39Å; K553-Y555 HydrophobicContact CB-CE2 4.2Å
554V88.3Confident71.4Confident0 Ų088.8 Ų88.80%047%0.468CS..EExtended strand (participates in β ladder)trans-117.2136.6176172.20000107.5W406 K411 T412 I413 I414 Y535 L536 L537W406-V554 HydrophobicContact CD2-CG1 4.42Å; W406-V554 HydrophobicContact CD2-CG2 4.12Å; W406-V554 HydrophobicContact CE3-CB 4.35Å; W406-V554 HydrophobicContact CE3-CG1 3.49Å; W406-V554 VanDerWaalsContact CE3-CG1 3.49Å; W406-V554 HydrophobicContact CE3-CG2 3.87Å; W406-V554 HydrophobicContact CZ3-CG1 3.79Å; W406-V554 HydrophobicContact CZ3-CG2 4.2Å; K411-V554 HydrophobicContact CB-CB 4.41Å; K411-V554 HydrophobicContact CB-CG2 3.79Å; K411-V554 HydrophobicContact CD-CG2 4.02Å; K411-V554 HydrophobicContact CG-CG2 3.76Å; T412-V554 PolarHBondContact O-N 3.44Å; I413-V554 CarbonylContact C-O 3.55Å; I413-V554 WeakPolarHBondContact CA-O 3.35Å; I414-V554 PolarHBondContact N-O 2.96Å; Y535-V554 HydrophobicContact CD1-CG1 3.99Å; Y535-V554 HydrophobicContact CG-CG1 3.91Å; L536-V554 WeakPolarHBondContact O-CA 3.37Å; L537-V554 HydrophobicContact CB-CG2 4.38Å; L537-V554 HydrophobicContact CD1-CG2 4.1Å
555Y88.9Confident71.9Confident97 Ų9788.9 Ų88.938%0.3847%0.465SS..EExtended strand (participates in β ladder)trans-110.6131.8-176.1-58.7-94.4000109.9I414 Y535 L536 P538 K553I414-Y555 HydrophobicContact CB-CD1 3.94Å; I414-Y555 HydrophobicContact CB-CE1 4.34Å; I414-Y555 HydrophobicContact CD1-CD1 3.86Å; I414-Y555 HydrophobicContact CD1-CE1 3.36Å; I414-Y555 HydrophobicContact CG1-CD1 4.45Å; I414-Y555 HydrophobicContact CG1-CE1 4.4Å; I414-Y555 HydrophobicContact CG2-CD1 4.02Å; I414-Y555 HydrophobicContact CG2-CE1 4.36Å; Y535-Y555 CarbonylContact C-O 3.58Å; Y535-Y555 WeakPolarHBondContact CA-O 3.4Å; L536-Y555 PolarHBondContact N-O 2.7Å; L536-Y555 PolarHBondContact O-N 3.27Å; P538-Y555 HydrophobicContact CG-CD2 4.03Å; P538-Y555 HydrophobicContact CG-CE2 3.83Å; K553-Y555 HydrophobicContact CB-CE2 4.2Å
556E89.7Confident72Confident50 Ų5089.1 Ų89.123%0.23445%0.451CS..EExtended strand (participates in β ladder)trans-77.5136.7169.5-168.9-178.4-154.600110.2I414 D415 F416 A533 Y535I414-E556 PolarHBondContact O-N 2.66Å; D415-E556 WeakPolarHBondContact CA-OE2 3.36Å; F416-E556 HydrophobicContact CB-CB 4.38Å; F416-E556 HydrophobicContact CB-CG 4.4Å; F416-E556 PolarHBondContact N-OE2 3.39Å; F416-E556 VanDerWaalsContact N-OE2 3.09Å; A533-E556 HydrophobicContact CB-CG 3.95Å; Y535-E556 HydrophobicContact CD1-CB 4.05Å; Y535-E556 HydrophobicContact CD1-CG 4.35Å; Y535-E556 HydrophobicContact CE1-CB 3.88Å; Y535-E556 HydrophobicContact CE1-CG 4.03Å
557A89.5Confident71.9Confident26 Ų2689.6 Ų89.622%0.21546%0.456CS..EExtended strand (participates in β ladder)trans-130.9129.7171.600000109.5A533 V534 L536A533-A557 CarbonylContact C-O 3.53Å; A533-A557 VanDerWaalsContact CA-O 3.28Å; A533-A557 WeakPolarHBondContact CA-O 3.47Å; V534-A557 HydrophobicContact CG2-CB 4.11Å; V534-A557 PolarHBondContact N-O 2.65Å; V534-A557 PolarHBondContact O-N 3.36Å; L536-A557 HydrophobicContact CD1-CB 3.77Å; L536-A557 HydrophobicContact CG-CB 4.34Å
558T88.9Confident73.3Confident62 Ų6288.7 Ų88.738%0.3845%0.446SS..EExtended strand (participates in β ladder)trans-72.8141.4177.250.40000110.9F416F416-T558 HydrophobicContact CB-CG2 4.21Å; F416-T558 HydrophobicContact CD1-CG2 3.53Å; F416-T558 HydrophobicContact CE1-CG2 4.01Å; F416-T558 HydrophobicContact CG-CG2 3.88Å
559I88.6Confident75.1Confident48 Ų4882.5 Ų82.525%0.24642%0.419CS..  trans-88.3115.7177.8-59175.9000108.6V531 N532 V534 K562V531-I559 HydrophobicContact CG1-CD1 3.77Å; N532-I559 PolarHBondContact O-N 2.89Å; V534-I559 HydrophobicContact CG1-CD1 3.72Å; V534-I559 HydrophobicContact CG1-CG1 3.95Å; I559-K562 HydrophobicContact CG2-CD 4.27Å; I559-K562 HydrophobicContact CG2-CG 3.61Å
560E85.9Confident76.4Confident91 Ų9182.5 Ų82.543%0.42540%0.395SS..  trans-88.7-39.8-179.7-75.5-74.9-15500113.4F490 K500 F508F490-E560 HydrophobicContact CE1-CB 4.47Å; F490-E560 HydrophobicContact CZ-CB 4.09Å; K500-E560 IonicContact NZ-OE1 2.69Å; K500-E560 PolarHBondContact NZ-OE1 3.1Å; K500-E560 IonicContact NZ-OE2 3.43Å; K500-E560 PolarHBondContact NZ-OE2 3.21Å; F508-E560 HydrophobicContact CD1-CG 4.38Å; F508-E560 HydrophobicContact CE1-CG 4.05Å
561E83.4Confident77.2Confident58 Ų5881.8 Ų81.827%0.27138%0.384SS..  trans-145.6145.6178.5-160.7178.5175.300110.8F490 T493 T563F490-E561 WeakPolarHBondContact CD2-OE2 3.07Å; F490-E561 HydrophobicContact CE2-CB 4.06Å; F490-E561 WeakPolarHBondContact CE2-OE2 2.96Å; F490-E561 HydrophobicContact CZ-CB 4.44Å; T493-E561 WeakPolarHBondContact CB-OE1 3.43Å; T493-E561 PolarHBondContact N-OE1 3Å; T493-E561 PolarHBondContact OG1-OE1 2.81Å; E561-T563 VanDerWaalsContact CD-CG2 3.49Å; E561-T563 HydrophobicContact CG-CG2 3.61Å; E561-T563 VanDerWaalsContact OE1-CG2 3.25Å; E561-T563 WeakPolarHBondContact OE1-CG2 3.25Å
562K83.5Confident77.3Confident53 Ų5380.4 Ų80.423%0.2338%0.38CS..  trans-127.1112174.5-55.6170.2-162.5163.30107.8V527 M528 V531 I559V527-K562 WeakPolarHBondContact O-CD 3.26Å; V527-K562 WeakPolarHBondContact O-CE 3.37Å; V527-K562 PolarHBondContact O-NZ 2.67Å; M528-K562 HydrophobicContact CE-CB 4.09Å; M528-K562 PolarHBondContact O-NZ 3.32Å; M528-K562 HydrophobicContact SD-CB 3.63Å; M528-K562 HydrophobicContact SD-CD 4.11Å; M528-K562 HydrophobicContact SD-CG 4.5Å; V531-K562 WeakPolarHBondContact O-CE 3.5Å; V531-K562 PolarHBondContact O-NZ 3.34Å; I559-K562 HydrophobicContact CG2-CD 4.27Å; I559-K562 HydrophobicContact CG2-CG 3.61Å
563T70.6Confident77Confident55 Ų5581.1 Ų81.134%0.33738%0.383SS..  trans-121146.3-175.170.90000111.2T493 E561 E565T493-T563 HydrophobicContact CG2-CG2 4.27Å; T493-T563 WeakPolarHBondContact OG1-CG2 3.38Å; E561-T563 VanDerWaalsContact CD-CG2 3.49Å; E561-T563 HydrophobicContact CG-CG2 3.61Å; E561-T563 VanDerWaalsContact OE1-CG2 3.25Å; E561-T563 WeakPolarHBondContact OE1-CG2 3.25Å; T563-E565 PolarHBondContact OG1-O 3.24Å
564K62.5Low76.3Confident131 Ų13178.3 Ų78.357%0.5737%0.373SS*.SBendtrans-81.4-28.7170.7-64.9-172.7-176.7175.80111.7L517L517-K564 VanDerWaalsContact O-CE 3.27Å; L517-K564 WeakPolarHBondContact O-CE 3.47Å; L517-K564 WeakPolarHBondContact O-CG 3.26Å
565E55.4Low75.4Confident143 Ų14384.3 Ų84.367%0.66840%0.402SS*.SBendtrans-100.9138-176.9-61.9-169.3177.500111.2T563 I567T563-E565 PolarHBondContact OG1-O 3.24Å; E565-I567 PolarHBondContact O-N 3.14Å
566Y46.5Very low74.2Confident145 Ų14583.3 Ų83.357%0.56940%0.404SS*.  trans-82.6104.5175.9-172.2-90.7000108.3R510 K512R510-Y566 PolarHBondContact NH2-OH 3.08Å; R510-Y566 VanDerWaalsContact NH2-OH 3.11Å; K512-Y566 HydrophobicContact CD-CD2 4.37Å
567I46.4Very low72.8Confident137 Ų13786.3 Ų86.370%0.70342%0.42SS*.  trans-1150166.6-49.3-169.7000108T493 R510 E565T493-I567 HydrophobicContact CG2-CB 4.45Å; T493-I567 HydrophobicContact CG2-CD1 3.71Å; T493-I567 HydrophobicContact CG2-CG1 4.19Å; R510-I567 PolarHBondContact NH1-O 3.13Å; R510-I567 PolarHBondContact NH1-OXT 2.91Å; E565-I567 PolarHBondContact O-N 3.14Å

Retrieved 567 of 567 residues in 231.6 ms (Link to these results)