A0A075BNB9_DROME Loading...

Cytochrome P450

AlphaFold DB , UniProt , Accession A0A075BNB9, Species DROME (Drosophila melanogaster, Fruit fly), Gene Cyp6a2, Length 506 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M74.3Confident90.9Very high170 Ų170112.5 Ų112.584%0.83758%0.576SS**  0-590-162.3165.968.100112.1V3 L4 I5M1-V3 PolarHBondContact O-N 2.77Å; M1-L4 PolarHBondContact O-N 3.04Å; M1-I5 HydrophobicContact CG-CD1 4.26Å; M1-I5 PolarHBondContact O-N 2.91Å
2F88.4Confident91Very high141 Ų141108.2 Ų108.262%0.61856%0.564SS**Hα-helixtrans-58-39.2179.8-65.7-75.2000115L4 I5 Y6F2-L4 VanDerWaalsContact C-N 3.34Å; F2-L4 PolarHBondContact O-N 2.77Å; F2-I5 PolarHBondContact O-N 3.25Å; F2-Y6 HydrophobicContact CB-CD2 4.37Å; F2-Y6 HydrophobicContact CB-CE2 4.11Å; F2-Y6 WeakPolarHBondContact O-CD2 3.15Å; F2-Y6 PolarHBondContact O-N 2.67Å
3V90.1Very high91.2Very high106 Ų106105.2 Ų105.264%0.64256%0.558SS**Hα-helixtrans-60.2-41.3176.61780000112.3M1 I5 Y6 L7M1-V3 PolarHBondContact O-N 2.77Å; V3-I5 VanDerWaalsContact C-N 3.33Å; V3-Y6 PolarHBondContact O-N 3.3Å; V3-L7 HydrophobicContact CG1-CD1 4.07Å; V3-L7 WeakPolarHBondContact O-CB 3.2Å; V3-L7 WeakPolarHBondContact O-CG 3.43Å; V3-L7 PolarHBondContact O-N 3.08Å
4L90.4Very high91.4Very high128 Ų128104.7 Ų104.767%0.6756%0.555SS**Hα-helixtrans-66.8-37.4177.2-68.5171.5000111.4M1 F2 L8M1-L4 PolarHBondContact O-N 3.04Å; F2-L4 VanDerWaalsContact C-N 3.34Å; F2-L4 PolarHBondContact O-N 2.77Å; L4-L8 WeakPolarHBondContact O-CB 3.47Å; L4-L8 PolarHBondContact O-N 3.27Å
5I93.1Very high91.2Very high79 Ų79104.7 Ų104.741%0.40555%0.554SS.*Hα-helixtrans-65.6-46.7176-64.2169.4000110.4M1 F2 V3 L7 L8 I9M1-I5 HydrophobicContact CG-CD1 4.26Å; M1-I5 PolarHBondContact O-N 2.91Å; F2-I5 PolarHBondContact O-N 3.25Å; V3-I5 VanDerWaalsContact C-N 3.33Å; I5-L7 PolarHBondContact O-N 2.72Å; I5-L8 PolarHBondContact O-N 2.84Å; I5-I9 HydrophobicContact CG2-CD1 3.86Å; I5-I9 WeakPolarHBondContact O-CG1 3.41Å; I5-I9 PolarHBondContact O-N 2.59Å
6Y94.6Very high91.2Very high159 Ų159101.8 Ų101.862%0.62455%0.549SS*.Hα-helixtrans-63.4-40.7177-72-59.4000112.6F2 V3 I9 A10F2-Y6 HydrophobicContact CB-CD2 4.37Å; F2-Y6 HydrophobicContact CB-CE2 4.11Å; F2-Y6 WeakPolarHBondContact O-CD2 3.15Å; F2-Y6 PolarHBondContact O-N 2.67Å; V3-Y6 PolarHBondContact O-N 3.3Å; Y6-I9 PolarHBondContact O-N 3.23Å; Y6-A10 VanDerWaalsContact O-CB 3.31Å; Y6-A10 WeakPolarHBondContact O-CB 3.33Å; Y6-A10 PolarHBondContact O-N 3.25Å
7L93.3Very high91.2Very high93 Ų93103.4 Ų103.449%0.48755%0.547SS..Hα-helixtrans-61.6-43.8173.7-76.7170.1000111.5V3 I5 A10 I11V3-L7 HydrophobicContact CG1-CD1 4.07Å; V3-L7 WeakPolarHBondContact O-CB 3.2Å; V3-L7 WeakPolarHBondContact O-CG 3.43Å; V3-L7 PolarHBondContact O-N 3.08Å; I5-L7 PolarHBondContact O-N 2.72Å; L7-A10 PolarHBondContact O-N 2.87Å; L7-I11 WeakPolarHBondContact O-CB 3.37Å; L7-I11 WeakPolarHBondContact O-CD1 3.31Å; L7-I11 WeakPolarHBondContact O-CG1 3.37Å; L7-I11 PolarHBondContact O-N 3.37Å
8L93.6Very high91Very high117 Ų117102.4 Ų102.461%0.61354%0.541SS*.Hα-helixtrans-62.8-43.2177.8-168107.7000111.7L4 I5 S12L4-L8 WeakPolarHBondContact O-CB 3.47Å; L4-L8 PolarHBondContact O-N 3.27Å; I5-L8 PolarHBondContact O-N 2.84Å; L8-S12 VanDerWaalsContact O-CB 3.25Å; L8-S12 WeakPolarHBondContact O-CB 3.41Å; L8-S12 PolarHBondContact O-N 2.91Å; L8-S12 PolarHBondContact O-OG 3.26Å
9I94.7Very high90.9Very high87 Ų87102 Ų10245%0.44653%0.532SS..Hα-helixtrans-64.8-45176.9-68167.6000110.7I5 Y6 S12 S13I5-I9 HydrophobicContact CG2-CD1 3.86Å; I5-I9 WeakPolarHBondContact O-CG1 3.41Å; I5-I9 PolarHBondContact O-N 2.59Å; Y6-I9 PolarHBondContact O-N 3.23Å; I9-S12 PolarHBondContact O-N 2.64Å; I9-S13 VanDerWaalsContact O-CB 3.3Å; I9-S13 WeakPolarHBondContact O-CB 3.32Å; I9-S13 PolarHBondContact O-N 2.89Å; I9-S13 PolarHBondContact O-OG 2.9Å
10A93.9Very high90.8Very high61 Ų61102.7 Ų102.750%0.50453%0.533SS..Hα-helixtrans-62.2-45.7178.600000111.6Y6 L7 S13 L14Y6-A10 VanDerWaalsContact O-CB 3.31Å; Y6-A10 WeakPolarHBondContact O-CB 3.33Å; Y6-A10 PolarHBondContact O-N 3.25Å; L7-A10 PolarHBondContact O-N 2.87Å; A10-S13 PolarHBondContact O-N 2.93Å; A10-L14 WeakPolarHBondContact O-CB 3.19Å; A10-L14 PolarHBondContact O-N 3.31Å
11I93.3Very high90.8Very high96 Ų96103.9 Ų103.949%0.49253%0.53SS..Hα-helixtrans-62.5-46.7175.9-69.1166.5000110.3L7 S13 L14 L15L7-I11 WeakPolarHBondContact O-CB 3.37Å; L7-I11 WeakPolarHBondContact O-CD1 3.31Å; L7-I11 WeakPolarHBondContact O-CG1 3.37Å; L7-I11 PolarHBondContact O-N 3.37Å; I11-S13 VanDerWaalsContact C-N 3.35Å; I11-S13 PolarHBondContact O-N 3.09Å; I11-L14 PolarHBondContact O-N 2.83Å; I11-L15 HydrophobicContact CG2-CD1 3.83Å; I11-L15 HydrophobicContact CG2-CG 4.28Å; I11-L15 WeakPolarHBondContact O-CB 3.13Å; I11-L15 VanDerWaalsContact O-CG 3.24Å; I11-L15 WeakPolarHBondContact O-CG 3.34Å; I11-L15 PolarHBondContact O-N 3.18Å
12S92.3Very high91.5Very high61 Ų6198.1 Ų98.143%0.42750%0.503SS..Hα-helixtrans-63.5-40.8-179.8-57.80000112L8 I9 L15 A16L8-S12 VanDerWaalsContact O-CB 3.25Å; L8-S12 WeakPolarHBondContact O-CB 3.41Å; L8-S12 PolarHBondContact O-N 2.91Å; L8-S12 PolarHBondContact O-OG 3.26Å; I9-S12 PolarHBondContact O-N 2.64Å; S12-L15 PolarHBondContact O-N 2.9Å; S12-A16 WeakPolarHBondContact O-CB 3.47Å; S12-A16 PolarHBondContact O-N 3.2Å
13S93.8Very high91.6Very high69 Ų6992.4 Ų92.448%0.48348%0.478SS..Hα-helixtrans-67.1-42.2177.1-56.50000111.6I9 A10 I11 A16 Y17I9-S13 VanDerWaalsContact O-CB 3.3Å; I9-S13 WeakPolarHBondContact O-CB 3.32Å; I9-S13 PolarHBondContact O-N 2.89Å; I9-S13 PolarHBondContact O-OG 2.9Å; A10-S13 PolarHBondContact O-N 2.93Å; I11-S13 VanDerWaalsContact C-N 3.35Å; I11-S13 PolarHBondContact O-N 3.09Å; S13-A16 PolarHBondContact O-N 3.04Å; S13-Y17 WeakPolarHBondContact O-CB 3.3Å; S13-Y17 PolarHBondContact O-N 3.48Å
14L93.3Very high91.7Very high99 Ų9989.5 Ų89.552%0.51846%0.458SS..Hα-helixtrans-62-45.4174.2178.262.5000111.1A10 I11 Y17 L18A10-L14 WeakPolarHBondContact O-CB 3.19Å; A10-L14 PolarHBondContact O-N 3.31Å; I11-L14 PolarHBondContact O-N 2.83Å; L14-Y17 PolarHBondContact O-N 2.84Å; L14-L18 HydrophobicContact CD1-CD1 4.22Å; L14-L18 HydrophobicContact CD1-CG 4.18Å; L14-L18 HydrophobicContact CG-CD1 4.09Å; L14-L18 HydrophobicContact CG-CG 4.44Å; L14-L18 WeakPolarHBondContact O-CB 3.37Å; L14-L18 VanDerWaalsContact O-CG 3.26Å; L14-L18 WeakPolarHBondContact O-CG 3.47Å; L14-L18 PolarHBondContact O-N 3.47Å
15L89.3Confident92Very high105 Ų10584.5 Ų84.555%0.5543%0.431SS..Hα-helixtrans-62.1-44.7176.8-72173.9000111.3I11 S12 Y17 L18 Y19I11-L15 HydrophobicContact CG2-CD1 3.83Å; I11-L15 HydrophobicContact CG2-CG 4.28Å; I11-L15 WeakPolarHBondContact O-CB 3.13Å; I11-L15 VanDerWaalsContact O-CG 3.24Å; I11-L15 WeakPolarHBondContact O-CG 3.34Å; I11-L15 PolarHBondContact O-N 3.18Å; S12-L15 PolarHBondContact O-N 2.9Å; L15-Y17 PolarHBondContact O-N 2.86Å; L15-L18 PolarHBondContact O-N 3.19Å; L15-Y19 WeakPolarHBondContact O-CB 3.31Å; L15-Y19 PolarHBondContact O-N 2.87Å
16A90.2Very high92.1Very high57 Ų5780.7 Ų80.747%0.47141%0.411SS..Hα-helixtrans-62-41.8176.100000112.1S12 S13 Y19 H20S12-A16 WeakPolarHBondContact O-CB 3.47Å; S12-A16 PolarHBondContact O-N 3.2Å; S13-A16 PolarHBondContact O-N 3.04Å; A16-Y19 PolarHBondContact O-N 3.41Å; A16-H20 VanDerWaalsContact O-CB 3.29Å; A16-H20 WeakPolarHBondContact O-CB 3.47Å; A16-H20 PolarHBondContact O-N 3.16Å
17Y92.1Very high92.2Very high130 Ų13078.1 Ų78.151%0.5141%0.408SS..Hα-helixtrans-64.4-47.9175.2171.5-106.2000112.1S13 L14 L15 Y19 H20 R21S13-Y17 WeakPolarHBondContact O-CB 3.3Å; S13-Y17 PolarHBondContact O-N 3.48Å; L14-Y17 PolarHBondContact O-N 2.84Å; L15-Y17 PolarHBondContact O-N 2.86Å; Y17-Y19 VanDerWaalsContact C-N 3.28Å; Y17-Y19 PolarHBondContact O-N 2.83Å; Y17-H20 PolarHBondContact O-N 2.82Å; Y17-R21 WeakPolarHBondContact O-CB 3.48Å; Y17-R21 PolarHBondContact O-N 3.46Å
18L88.4Confident92.2Very high85 Ų8579.6 Ų79.645%0.44541%0.407SS..Hα-helixtrans-61.3-41.1177.6-71.4175.9000111.2L14 L15 R21 N22L14-L18 HydrophobicContact CD1-CD1 4.22Å; L14-L18 HydrophobicContact CD1-CG 4.18Å; L14-L18 HydrophobicContact CG-CD1 4.09Å; L14-L18 HydrophobicContact CG-CG 4.44Å; L14-L18 WeakPolarHBondContact O-CB 3.37Å; L14-L18 VanDerWaalsContact O-CG 3.26Å; L14-L18 WeakPolarHBondContact O-CG 3.47Å; L14-L18 PolarHBondContact O-N 3.47Å; L15-L18 PolarHBondContact O-N 3.19Å; L18-R21 PolarHBondContact O-N 3.45Å; L18-N22 VanDerWaalsContact O-CB 3.24Å; L18-N22 WeakPolarHBondContact O-CB 3.37Å; L18-N22 PolarHBondContact O-N 2.89Å
19Y87.4Confident92.2Very high95 Ų9577.4 Ų77.437%0.37339%0.391SS..Hα-helixtrans-62-52.4176.4-178.4-94.6000111.8L15 A16 Y17 R21 N22 F23 P38L15-Y19 WeakPolarHBondContact O-CB 3.31Å; L15-Y19 PolarHBondContact O-N 2.87Å; A16-Y19 PolarHBondContact O-N 3.41Å; Y17-Y19 VanDerWaalsContact C-N 3.28Å; Y17-Y19 PolarHBondContact O-N 2.83Å; Y19-R21 VanDerWaalsContact C-N 3.34Å; Y19-R21 PolarHBondContact O-N 3.3Å; Y19-N22 PolarHBondContact O-N 2.91Å; Y19-N22 VanDerWaalsContact O-N 3.15Å; Y19-F23 HydrophobicContact CD2-CD2 4.22Å; Y19-F23 AromaticContact CD2-CE2 3.95Å; Y19-F23 HydrophobicContact CD2-CE2 3.95Å; Y19-F23 HydrophobicContact CE1-CD1 4.24Å; Y19-F23 HydrophobicContact CE1-CD2 4.37Å; Y19-F23 HydrophobicContact CE1-CE1 4.43Å; Y19-F23 HydrophobicContact CE1-CE2 4.5Å; Y19-F23 HydrophobicContact CE1-CG 4.29Å; Y19-F23 AromaticContact CE2-CD2 3.97Å; Y19-F23 HydrophobicContact CE2-CD2 3.97Å; Y19-F23 HydrophobicContact CE2-CE1 4.21Å; Y19-F23 AromaticContact CE2-CE2 3.41Å; Y19-F23 HydrophobicContact CE2-CE2 3.41Å; Y19-F23 VanDerWaalsContact CE2-CE2 3.41Å; Y19-F23 AromaticContact CE2-CZ 3.59Å; Y19-F23 HydrophobicContact CE2-CZ 3.59Å; Y19-F23 AromaticContact CZ-CD1 3.99Å; Y19-F23 AromaticContact CZ-CE1 3.74Å; Y19-F23 AromaticContact CZ-CE2 3.74Å; Y19-F23 AromaticContact CZ-CZ 3.61Å; Y19-F23 WeakPolarHBondContact O-CD2 3.49Å; Y19-F23 PolarHBondContact O-N 3.35Å; Y19-F23 VanDerWaalsContact OH-CE1 3.28Å; Y19-F23 WeakPolarHBondContact OH-CE1 3.37Å; Y19-F23 WeakPolarHBondContact OH-CZ 3.13Å; Y19-P38 WeakPolarHBondContact OH-CA 3.48Å; Y19-P38 WeakPolarHBondContact OH-CB 3.5Å; Y19-P38 PolarHBondContact OH-O 3.31Å
20H89.3Confident92.2Very high116 Ų11676 Ų7654%0.53740%0.398SS..Hα-helixtrans-60.7-42.8176.6-176.678.9000111.9A16 Y17 N22 F23 N24A16-H20 VanDerWaalsContact O-CB 3.29Å; A16-H20 WeakPolarHBondContact O-CB 3.47Å; A16-H20 PolarHBondContact O-N 3.16Å; Y17-H20 PolarHBondContact O-N 2.82Å; H20-N22 VanDerWaalsContact C-N 3.28Å; H20-N22 PolarHBondContact O-N 3.48Å; H20-F23 PolarHBondContact O-N 2.96Å; H20-N24 PolarHBondContact CE1-ND2 3.12Å; H20-N24 PolarHBondContact NE2-ND2 2.91Å; H20-N24 WeakPolarHBondContact O-CB 3.44Å; H20-N24 PolarHBondContact O-N 3.38Å
21R90.3Very high92.3Very high128 Ų12873.3 Ų73.348%0.48338%0.375SS..Hα-helixtrans-61.6-37.6176.4-176178.7175.8-179.50.3111.5Y17 L18 Y19 R28Y17-R21 WeakPolarHBondContact O-CB 3.48Å; Y17-R21 PolarHBondContact O-N 3.46Å; L18-R21 PolarHBondContact O-N 3.45Å; Y19-R21 VanDerWaalsContact C-N 3.34Å; Y19-R21 PolarHBondContact O-N 3.3Å; R21-R28 VanDerWaalsContact O-CZ 3.26Å; R21-R28 PolarHBondContact O-NH1 2.9Å; R21-R28 PolarHBondContact O-NH2 3.31Å
22N89.6Confident92.5Very high48 Ų4870.4 Ų70.426%0.25736%0.363SS..Hα-helixtrans-72.1-43.5178.4-177.469.7000111.9L18 Y19 H20 N24 Y25 Y74 H77 P79L18-N22 VanDerWaalsContact O-CB 3.24Å; L18-N22 WeakPolarHBondContact O-CB 3.37Å; L18-N22 PolarHBondContact O-N 2.89Å; Y19-N22 PolarHBondContact O-N 2.91Å; Y19-N22 VanDerWaalsContact O-N 3.15Å; H20-N22 VanDerWaalsContact C-N 3.28Å; H20-N22 PolarHBondContact O-N 3.48Å; N22-N24 PolarHBondContact O-N 3.45Å; N22-Y25 WeakPolarHBondContact O-CB 3.28Å; N22-Y25 PolarHBondContact O-N 2.99Å; N22-Y25 VanDerWaalsContact O-N 3.08Å; N22-Y74 VanDerWaalsContact O-CE1 3.3Å; N22-Y74 WeakPolarHBondContact O-CE1 3.34Å; N22-Y74 PolarHBondContact O-OH 3.38Å; N22-H77 PolarHBondContact ND2-O 2.85Å; N22-P79 WeakPolarHBondContact OD1-CD 3.24Å
23F90.8Very high92.7Very high21 Ų2169.5 Ų69.59%0.09235%0.352CS..Hα-helixtrans-73.4-15.4-179.6-81-129.2000113.1Y19 H20 P36 Y74 H77Y19-F23 HydrophobicContact CD2-CD2 4.22Å; Y19-F23 AromaticContact CD2-CE2 3.95Å; Y19-F23 HydrophobicContact CD2-CE2 3.95Å; Y19-F23 HydrophobicContact CE1-CD1 4.24Å; Y19-F23 HydrophobicContact CE1-CD2 4.37Å; Y19-F23 HydrophobicContact CE1-CE1 4.43Å; Y19-F23 HydrophobicContact CE1-CE2 4.5Å; Y19-F23 HydrophobicContact CE1-CG 4.29Å; Y19-F23 AromaticContact CE2-CD2 3.97Å; Y19-F23 HydrophobicContact CE2-CD2 3.97Å; Y19-F23 HydrophobicContact CE2-CE1 4.21Å; Y19-F23 AromaticContact CE2-CE2 3.41Å; Y19-F23 HydrophobicContact CE2-CE2 3.41Å; Y19-F23 VanDerWaalsContact CE2-CE2 3.41Å; Y19-F23 AromaticContact CE2-CZ 3.59Å; Y19-F23 HydrophobicContact CE2-CZ 3.59Å; Y19-F23 AromaticContact CZ-CD1 3.99Å; Y19-F23 AromaticContact CZ-CE1 3.74Å; Y19-F23 AromaticContact CZ-CE2 3.74Å; Y19-F23 AromaticContact CZ-CZ 3.61Å; Y19-F23 WeakPolarHBondContact O-CD2 3.49Å; Y19-F23 PolarHBondContact O-N 3.35Å; Y19-F23 VanDerWaalsContact OH-CE1 3.28Å; Y19-F23 WeakPolarHBondContact OH-CE1 3.37Å; Y19-F23 WeakPolarHBondContact OH-CZ 3.13Å; H20-F23 PolarHBondContact O-N 2.96Å; F23-P36 HydrophobicContact CB-CG 4Å; F23-P36 HydrophobicContact CD1-CB 3.75Å; F23-P36 HydrophobicContact CD1-CG 3.31Å; F23-P36 HydrophobicContact CE1-CB 3.72Å; F23-P36 HydrophobicContact CE1-CG 3.85Å; F23-P36 HydrophobicContact CG-CG 3.85Å; F23-Y74 PolarHBondContact O-OH 2.8Å; F23-H77 HydrophobicContact CE2-CB 3.81Å; F23-H77 HydrophobicContact CZ-CB 4.12Å
24N92.8Very high92.8Very high45 Ų4568.6 Ų68.624%0.24134%0.341CS..THydrogen-bonded Turntrans-97.512.8169.3-84-44.2000114.1H20 N22 W26 R28H20-N24 PolarHBondContact CE1-ND2 3.12Å; H20-N24 PolarHBondContact NE2-ND2 2.91Å; H20-N24 WeakPolarHBondContact O-CB 3.44Å; H20-N24 PolarHBondContact O-N 3.38Å; N22-N24 PolarHBondContact O-N 3.45Å; N24-W26 PolarHBondContact O-N 2.82Å; N24-R28 WeakPolarHBondContact O-CG 3.25Å; N24-R28 PolarHBondContact O-N 2.87Å; N24-R28 VanDerWaalsContact O-N 3.14Å
25Y95.6Very high92.8Very high23 Ų2368.1 Ų68.19%0.0935%0.352CS..THydrogen-bonded Turntrans-57.1-48.9-177174.9-85.7000112.6N22 R29 Y74 P79 E398 T401N22-Y25 WeakPolarHBondContact O-CB 3.28Å; N22-Y25 PolarHBondContact O-N 2.99Å; N22-Y25 VanDerWaalsContact O-N 3.08Å; Y25-R29 PolarHBondContact O-NH1 2.71Å; Y25-R29 PolarHBondContact OH-NE 3.25Å; Y25-Y74 WeakPolarHBondContact CB-OH 3.25Å; Y25-Y74 PolarHBondContact N-OH 2.97Å; Y25-Y74 VanDerWaalsContact N-OH 3.15Å; Y25-P79 HydrophobicContact CD1-CB 3.73Å; Y25-P79 HydrophobicContact CD1-CG 4.28Å; Y25-P79 HydrophobicContact CD2-CG 4.4Å; Y25-P79 HydrophobicContact CE1-CB 4.25Å; Y25-P79 HydrophobicContact CG-CB 4.01Å; Y25-P79 HydrophobicContact CG-CG 4.15Å; Y25-E398 VanDerWaalsContact CE2-OE2 3.26Å; Y25-E398 WeakPolarHBondContact CE2-OE2 3.39Å; Y25-E398 PolarHBondContact OH-OE2 2.69Å; Y25-T401 PolarHBondContact OH-OG1 3.48Å
26W96.5Very high92.9Very high0 Ų064.1 Ų64.10%033%0.332CS..THydrogen-bonded Turntrans-75.4-36.1-177.7-66.3121.4000113N24 R28 R29 G30 V31 H33 F70 G72 F73 Y74 P79 A80 A81 T401N24-W26 PolarHBondContact O-N 2.82Å; W26-R28 VanDerWaalsContact C-N 3.34Å; W26-R28 PolarHBondContact O-N 3.18Å; W26-R29 CarbonylContact O-C 3.57Å; W26-R29 PolarHBondContact O-N 2.91Å; W26-G30 PolarHBondContact O-N 3.23Å; W26-V31 HydrophobicContact CB-CB 4.47Å; W26-V31 HydrophobicContact CD2-CB 4.5Å; W26-V31 HydrophobicContact CE3-CB 3.7Å; W26-V31 HydrophobicContact CE3-CG1 3.88Å; W26-V31 HydrophobicContact CE3-CG2 3.8Å; W26-V31 HydrophobicContact CZ3-CB 4.38Å; W26-V31 HydrophobicContact CZ3-CG1 4.32Å; W26-V31 HydrophobicContact CZ3-CG2 4.11Å; W26-V31 PolarHBondContact O-N 2.77Å; W26-H33 HydrophobicContact CB-CB 4.12Å; W26-H33 WeakPolarHBondContact CB-ND1 3.49Å; W26-H33 HydrophobicContact CG-CB 4.45Å; W26-F70 HydrophobicContact CH2-CE2 4.06Å; W26-F70 AromaticContact CZ3-CE2 3.65Å; W26-F70 HydrophobicContact CZ3-CE2 3.65Å; W26-F70 HydrophobicContact CZ3-CZ 4.44Å; W26-G72 VanDerWaalsContact CD1-CA 3.45Å; W26-G72 VanDerWaalsContact CE2-CA 3.41Å; W26-G72 VanDerWaalsContact CG-CA 3.48Å; W26-F73 PolarHBondContact NE1-O 2.76Å; W26-F73 VanDerWaalsContact NE1-O 3.1Å; W26-Y74 AromaticContact CD1-CE2 3.43Å; W26-Y74 VanDerWaalsContact CD1-CE2 3.43Å; W26-Y74 AromaticContact CD1-CZ 3.7Å; W26-Y74 HydrophobicContact CG-CE2 4.48Å; W26-P79 HydrophobicContact CZ2-CB 4.31Å; W26-A80 WeakPolarHBondContact CZ2-O 3.37Å; W26-A81 HydrophobicContact CH2-CB 4.03Å; W26-T401 HydrophobicContact CH2-CG2 3.97Å; W26-T401 HydrophobicContact CZ2-CG2 4.17Å
27N94.9Very high93Very high104 Ų10465.2 Ų65.256%0.55633%0.327SS*.G310 helixtrans-58.2-45175.5-170.534.8000111.9R29 G30 H33N27-R29 PolarHBondContact O-N 2.79Å; N27-R29 VanDerWaalsContact O-N 3.07Å; N27-G30 PolarHBondContact O-N 3.34Å; N27-G30 VanDerWaalsContact O-N 3.14Å; N27-H33 PolarHBondContact N-CE1 3.09Å
28R93.9Very high92.8Very high124 Ų12462.9 Ų62.947%0.46833%0.328SS..G310 helixtrans-62.2-16.6176.3-72.6-164.2-56.1-89.5-3114.4R21 N24 W26R21-R28 VanDerWaalsContact O-CZ 3.26Å; R21-R28 PolarHBondContact O-NH1 2.9Å; R21-R28 PolarHBondContact O-NH2 3.31Å; N24-R28 WeakPolarHBondContact O-CG 3.25Å; N24-R28 PolarHBondContact O-N 2.87Å; N24-R28 VanDerWaalsContact O-N 3.14Å; W26-R28 VanDerWaalsContact C-N 3.34Å; W26-R28 PolarHBondContact O-N 3.18Å
29R94.1Very high92.5Very high72 Ų7263.1 Ų63.127%0.27233%0.329SS..G310 helixtrans-105.50.4-178.2-71.4170.4179.374.62.8113Y25 W26 N27 V31 E398Y25-R29 PolarHBondContact O-NH1 2.71Å; Y25-R29 PolarHBondContact OH-NE 3.25Å; W26-R29 CarbonylContact O-C 3.57Å; W26-R29 PolarHBondContact O-N 2.91Å; N27-R29 PolarHBondContact O-N 2.79Å; N27-R29 VanDerWaalsContact O-N 3.07Å; R29-V31 HydrophobicContact CB-CG2 3.98Å; R29-V31 PolarHBondContact O-N 3.47Å; R29-E398 VanDerWaalsContact CZ-CD 3.49Å; R29-E398 IonicContact CZ-OE1 2.73Å; R29-E398 IonicContact CZ-OE2 3.31Å; R29-E398 IonicContact NE-OE1 3.73Å; R29-E398 PolarHBondContact NE-OE1 3.11Å; R29-E398 IonicContact NE-OE2 2.74Å; R29-E398 PolarHBondContact NE-OE2 3.33Å; R29-E398 IonicContact NH2-OE1 3.93Å; R29-E398 PolarHBondContact NH2-OE1 2.91Å; R29-E398 IonicContact NH2-OE2 2.64Å; R29-E398 PolarHBondContact NH2-OE2 3.49Å
30G93.8Very high92.6Very high57 Ų5761.3 Ų61.359%0.58832%0.322SS*.THydrogen-bonded Turntrans62.425.3-176.700000113.5W26 N27W26-G30 PolarHBondContact O-N 3.23Å; N27-G30 PolarHBondContact O-N 3.34Å; N27-G30 VanDerWaalsContact O-N 3.14Å
31V96.8Very high92.7Very high5 Ų555.8 Ų55.83%0.0330%0.297CS..  trans-92127.4177.1-179.30000108.7W26 R29 H33 F70 G72 L395W26-V31 HydrophobicContact CB-CB 4.47Å; W26-V31 HydrophobicContact CD2-CB 4.5Å; W26-V31 HydrophobicContact CE3-CB 3.7Å; W26-V31 HydrophobicContact CE3-CG1 3.88Å; W26-V31 HydrophobicContact CE3-CG2 3.8Å; W26-V31 HydrophobicContact CZ3-CB 4.38Å; W26-V31 HydrophobicContact CZ3-CG1 4.32Å; W26-V31 HydrophobicContact CZ3-CG2 4.11Å; W26-V31 PolarHBondContact O-N 2.77Å; R29-V31 HydrophobicContact CB-CG2 3.98Å; R29-V31 PolarHBondContact O-N 3.47Å; V31-H33 PolarHBondContact O-N 2.61Å; V31-H33 PolarHBondContact O-ND1 2.92Å; V31-F70 HydrophobicContact CG1-CD2 4.18Å; V31-F70 HydrophobicContact CG1-CE2 3.79Å; V31-F70 HydrophobicContact CG2-CE2 4.09Å; V31-F70 HydrophobicContact CG2-CZ 4.26Å; V31-G72 VanDerWaalsContact CG1-N 3.31Å; V31-L395 HydrophobicContact CG2-CD2 4.34Å
32P96.8Very high92.9Very high35 Ų3550.8 Ų50.823%0.22728%0.28CS..  trans-56.9137.7175.2-23.132.5000111.4Y63 F68 V71 G72P32-Y63 HydrophobicContact CB-CD1 4.4Å; P32-Y63 HydrophobicContact CB-CE1 4.01Å; P32-F68 VanDerWaalsContact CD-CE1 3.5Å; P32-F68 HydrophobicContact CG-CD1 3.94Å; P32-F68 HydrophobicContact CG-CD2 3.62Å; P32-F68 HydrophobicContact CG-CE1 3.85Å; P32-F68 HydrophobicContact CG-CE2 3.52Å; P32-F68 HydrophobicContact CG-CG 3.84Å; P32-F68 HydrophobicContact CG-CZ 3.64Å; P32-V71 HydrophobicContact CB-CG1 4.15Å; P32-V71 WeakPolarHBondContact O-CB 3.48Å; P32-G72 PolarHBondContact O-N 2.68Å
33H96.5Very high93.1Very high42 Ų4248.5 Ų48.519%0.19427%0.268CS..BIsolated β-bridgetrans-164.9160.817961.4-69.8000110.2W26 N27 V31 Y63 G72W26-H33 HydrophobicContact CB-CB 4.12Å; W26-H33 WeakPolarHBondContact CB-ND1 3.49Å; W26-H33 HydrophobicContact CG-CB 4.45Å; N27-H33 PolarHBondContact N-CE1 3.09Å; V31-H33 PolarHBondContact O-N 2.61Å; V31-H33 PolarHBondContact O-ND1 2.92Å; H33-Y63 PolarHBondContact O-OH 3.19Å; H33-G72 WeakPolarHBondContact CB-O 3.47Å
34D95.8Very high93.1Very high49 Ų4951.2 Ų51.226%0.26229%0.286SS..PPolyproline II helixtrans-84.3144.7166.2-78.8-25000111.7P36 N42 Y59 K62 Y63D34-P36 VanDerWaalsContact O-CD 3.29Å; D34-P36 WeakPolarHBondContact O-CD 2.85Å; D34-P36 VanDerWaalsContact O-N 3.16Å; D34-N42 WeakPolarHBondContact CB-ND2 3.07Å; D34-N42 PolarHBondContact O-ND2 3.49Å; D34-N42 VanDerWaalsContact O-ND2 3.16Å; D34-Y59 HydrophobicContact CB-CE2 3.94Å; D34-Y59 PolarHBondContact N-OH 3.4Å; D34-K62 WeakPolarHBondContact OD1-CE 3.25Å; D34-K62 IonicContact OD1-NZ 3.12Å; D34-K62 PolarHBondContact OD1-NZ 3.45Å; D34-K62 IonicContact OD2-NZ 2.71Å; D34-K62 PolarHBondContact OD2-NZ 2.92Å; D34-Y63 PolarHBondContact N-OH 3.07Å; D34-Y63 PolarHBondContact OD1-OH 2.78Å; D34-Y63 VanDerWaalsContact OD1-OH 3.09Å
35A93.2Very high92.8Very high90 Ų9049.4 Ų49.474%0.74428%0.278SS*.PPolyproline II helixtrans-56.7119.5172.400000109.8
36P93Very high92.4Very high21 Ų2149.3 Ų49.314%0.13628%0.278CS..PPolyproline II helixtrans-70.4135.6-176.824.3-33.3000112.5F23 D34 Y74F23-P36 HydrophobicContact CB-CG 4Å; F23-P36 HydrophobicContact CD1-CB 3.75Å; F23-P36 HydrophobicContact CD1-CG 3.31Å; F23-P36 HydrophobicContact CE1-CB 3.72Å; F23-P36 HydrophobicContact CE1-CG 3.85Å; F23-P36 HydrophobicContact CG-CG 3.85Å; D34-P36 VanDerWaalsContact O-CD 3.29Å; D34-P36 WeakPolarHBondContact O-CD 2.85Å; D34-P36 VanDerWaalsContact O-N 3.16Å; P36-Y74 HydrophobicContact CB-CD1 4.34Å; P36-Y74 HydrophobicContact CB-CD2 3.54Å; P36-Y74 HydrophobicContact CB-CE2 4.12Å; P36-Y74 HydrophobicContact CB-CG 3.66Å; P36-Y74 HydrophobicContact CG-CD1 4.43Å; P36-Y74 HydrophobicContact CG-CD2 3.58Å; P36-Y74 HydrophobicContact CG-CE1 4.48Å; P36-Y74 HydrophobicContact CG-CE2 3.61Å; P36-Y74 HydrophobicContact CG-CG 4.01Å
37H92.4Very high91.8Very high79 Ų7950.8 Ų50.837%0.36628%0.283SS..BIsolated β-bridgetrans-65.6140.6169.6179.5-87.7000110.6L39 Y40 G41 V44H37-L39 VanDerWaalsContact C-N 3.28Å; H37-L39 PolarHBondContact ND1-N 3.31Å; H37-L39 PolarHBondContact O-N 3.47Å; H37-Y40 AromaticContact CE1-CD2 3.82Å; H37-Y40 AromaticContact ND1-CD2 3.63Å; H37-Y40 PolarHBondContact ND1-N 2.97Å; H37-Y40 PolarHBondContact O-N 3.23Å; H37-G41 VanDerWaalsContact CB-O 3.24Å; H37-G41 WeakPolarHBondContact CB-O 3.33Å; H37-G41 PolarHBondContact N-O 3.48Å; H37-G41 WeakPolarHBondContact O-CA 3.16Å; H37-G41 PolarHBondContact O-N 3.04Å; H37-V44 HydrophobicContact CB-CG2 3.41Å; H37-V44 VanDerWaalsContact CB-CG2 3.41Å
38P85.9Confident91.3Very high82 Ų8253.3 Ų53.353%0.53229%0.29SS..THydrogen-bonded Turntrans-54.7-37-169.6-34.337.7000117.2Y19Y19-P38 WeakPolarHBondContact OH-CA 3.48Å; Y19-P38 WeakPolarHBondContact OH-CB 3.5Å; Y19-P38 PolarHBondContact OH-O 3.31Å
39L83.6Confident91.1Very high89 Ų8952.8 Ų52.847%0.46630%0.296SS..THydrogen-bonded Turntrans-101.2-29.4-178.3-173.862.3000114H37H37-L39 VanDerWaalsContact C-N 3.28Å; H37-L39 PolarHBondContact ND1-N 3.31Å; H37-L39 PolarHBondContact O-N 3.47Å
40Y88.5Confident91Very high57 Ų5752.8 Ų52.822%0.22430%0.296CS..THydrogen-bonded Turntrans-114.2-4.3-165.6-71.7-71.3000112.9H37 N42 M43 M225H37-Y40 AromaticContact CE1-CD2 3.82Å; H37-Y40 AromaticContact ND1-CD2 3.63Å; H37-Y40 PolarHBondContact ND1-N 2.97Å; H37-Y40 PolarHBondContact O-N 3.23Å; Y40-N42 PolarHBondContact O-N 3.05Å; Y40-M43 PolarHBondContact O-N 2.73Å; Y40-M225 HydrophobicContact CE1-SD 4.37Å
41G92.7Very high90.9Very high1 Ų150.8 Ų50.81%0.0127%0.272CS..BIsolated β-bridgetrans58.2-128.4-170.900000110.4H37 M43 L76H37-G41 VanDerWaalsContact CB-O 3.24Å; H37-G41 WeakPolarHBondContact CB-O 3.33Å; H37-G41 PolarHBondContact N-O 3.48Å; H37-G41 WeakPolarHBondContact O-CA 3.16Å; H37-G41 PolarHBondContact O-N 3.04Å; G41-M43 VanDerWaalsContact C-N 3.31Å; G41-L76 WeakPolarHBondContact CA-O 3.38Å; G41-L76 PolarHBondContact N-O 3.15Å
42N94.7Very high90.7Very high23 Ų2351.7 Ų51.712%0.12328%0.277CS..THydrogen-bonded Turntrans-90.610176-57.2113.7000113.3D34 Y40 Y59 F73 Y74D34-N42 WeakPolarHBondContact CB-ND2 3.07Å; D34-N42 PolarHBondContact O-ND2 3.49Å; D34-N42 VanDerWaalsContact O-ND2 3.16Å; Y40-N42 PolarHBondContact O-N 3.05Å; N42-Y59 HydrophobicContact CB-CE2 4.16Å; N42-F73 HydrophobicContact CB-CD2 3.78Å; N42-F73 HydrophobicContact CB-CE2 3.53Å; N42-F73 HydrophobicContact CB-CG 4.49Å; N42-F73 HydrophobicContact CB-CZ 4.06Å; N42-Y74 PolarHBondContact N-O 3.37Å; N42-Y74 WeakPolarHBondContact OD1-CB 3.46Å; N42-Y74 PolarHBondContact OD1-N 3.23Å
43M92.3Very high90.6Very high0 Ų050.9 Ų50.90%027%0.27CS..  trans-11045.4-175.5-55.4-177.774.800113Y40 G41 G45 F46 M52 F55 F56 F73 F75Y40-M43 PolarHBondContact O-N 2.73Å; G41-M43 VanDerWaalsContact C-N 3.31Å; M43-G45 PolarHBondContact O-N 2.69Å; M43-G45 VanDerWaalsContact O-N 3.13Å; M43-F46 HydrophobicContact CB-CB 4.01Å; M43-F46 HydrophobicContact CE-CD2 3.64Å; M43-F46 HydrophobicContact CE-CE2 3.94Å; M43-F46 HydrophobicContact CE-CG 4.19Å; M43-F46 WeakPolarHBondContact O-CB 3.4Å; M43-F46 PolarHBondContact O-N 2.66Å; M43-M52 HydrophobicContact CE-CG 4.02Å; M43-F55 VanDerWaalsContact C-CE1 3.4Å; M43-F55 HydrophobicContact CB-CD1 4.38Å; M43-F55 HydrophobicContact CB-CD2 4.4Å; M43-F55 HydrophobicContact CB-CE1 4.42Å; M43-F55 HydrophobicContact CB-CE2 4.45Å; M43-F55 HydrophobicContact CB-CG 4.37Å; M43-F55 HydrophobicContact CB-CZ 4.45Å; M43-F55 HydrophobicContact CE-CD2 4.11Å; M43-F55 HydrophobicContact CG-CG 4.48Å; M43-F56 HydrophobicContact CE-CZ 4.41Å; M43-F73 HydrophobicContact CG-CE1 4.13Å; M43-F73 HydrophobicContact CG-CZ 3.65Å; M43-F73 HydrophobicContact SD-CE1 4.28Å; M43-F73 HydrophobicContact SD-CZ 4.26Å; M43-F75 HydrophobicContact CE-CD2 4.4Å; M43-F75 HydrophobicContact CE-CE2 3.87Å; M43-F75 HydrophobicContact CE-CZ 4.2Å; M43-F75 HydrophobicContact SD-CD1 4.29Å; M43-F75 HydrophobicContact SD-CD2 3.53Å; M43-F75 VanDerWaalsContact SD-CD2 3.53Å; M43-F75 HydrophobicContact SD-CE1 4.3Å; M43-F75 HydrophobicContact SD-CE2 3.55Å; M43-F75 VanDerWaalsContact SD-CE2 3.55Å; M43-F75 HydrophobicContact SD-CG 3.93Å; M43-F75 HydrophobicContact SD-CZ 3.94Å
44V91.8Very high90.5Very high78 Ų7851.7 Ų51.747%0.47328%0.275SS..THydrogen-bonded Turntrans-63114.3-178.6179.10000110.9H37 F55H37-V44 HydrophobicContact CB-CG2 3.41Å; H37-V44 VanDerWaalsContact CB-CG2 3.41Å; V44-F55 WeakPolarHBondContact O-CE1 3.43Å; V44-F55 VanDerWaalsContact O-CZ 3.31Å; V44-F55 WeakPolarHBondContact O-CZ 3.36Å
45G87.1Confident90.5Very high7 Ų749.7 Ų49.77%0.07226%0.264CS..THydrogen-bonded Turntrans105.8-0.4-175.200000114.4M43 R47 K48 N49 R50M43-G45 PolarHBondContact O-N 2.69Å; M43-G45 VanDerWaalsContact O-N 3.13Å; G45-R47 PolarHBondContact O-N 3.47Å; G45-K48 WeakPolarHBondContact O-CB 3.41Å; G45-K48 PolarHBondContact O-N 3.29Å; G45-N49 VanDerWaalsContact CA-OD1 3.22Å; G45-N49 WeakPolarHBondContact CA-OD1 3.45Å; G45-N49 PolarHBondContact O-N 2.67Å; G45-N49 PolarHBondContact O-OD1 3.24Å; G45-R50 PolarHBondContact O-N 3.12Å
46F86.9Confident90.7Very high21 Ų2145.4 Ų45.49%0.09223%0.229CC..BIsolated β-bridgetrans-55.3128.8176.3179.3-114.9000111.8M43 K48 M52 F55 L76M43-F46 HydrophobicContact CB-CB 4.01Å; M43-F46 HydrophobicContact CE-CD2 3.64Å; M43-F46 HydrophobicContact CE-CE2 3.94Å; M43-F46 HydrophobicContact CE-CG 4.19Å; M43-F46 WeakPolarHBondContact O-CB 3.4Å; M43-F46 PolarHBondContact O-N 2.66Å; F46-K48 PolarHBondContact O-N 2.72Å; F46-K48 VanDerWaalsContact O-N 3.15Å; F46-M52 HydrophobicContact CD2-CG 4.21Å; F46-M52 HydrophobicContact CE2-CG 3.74Å; F46-M52 HydrophobicContact CE2-SD 4.03Å; F46-F55 HydrophobicContact CB-CE2 4.07Å; F46-F55 HydrophobicContact CB-CZ 4.35Å; F46-F55 HydrophobicContact CD2-CE2 4.45Å; F46-L76 HydrophobicContact CD1-CD2 4.41Å
47R82.5Confident90.8Very high30 Ų3047.8 Ų47.811%0.11324%0.236CC..THydrogen-bonded Turntrans54.527-175.5-61.1-169.9178.3-125.221114.7G45 M217 K221 P488 T489G45-R47 PolarHBondContact O-N 3.47Å; R47-M217 VanDerWaalsContact CD-CE 3.49Å; R47-K221 PolarHBondContact O-NZ 3.24Å; R47-P488 WeakPolarHBondContact CA-O 3.49Å; R47-T489 PolarHBondContact NH1-O 3.03Å
48K86.1Confident91Very high158 Ų15848 Ų4869%0.68724%0.239SC*.THydrogen-bonded Turntrans-124.3-63.4172.2-172.3178.6179.3-177.80111.4G45 F46 P488G45-K48 WeakPolarHBondContact O-CB 3.41Å; G45-K48 PolarHBondContact O-N 3.29Å; F46-K48 PolarHBondContact O-N 2.72Å; F46-K48 VanDerWaalsContact O-N 3.15Å; K48-P488 WeakPolarHBondContact O-CG 3.38Å
49N89Confident91.6Very high113 Ų11344.6 Ų44.660%0.60422%0.216SC*.THydrogen-bonded Turntrans-144.90.3-172.364.6-24.5000114.7G45G45-N49 VanDerWaalsContact CA-OD1 3.22Å; G45-N49 WeakPolarHBondContact CA-OD1 3.45Å; G45-N49 PolarHBondContact O-N 2.67Å; G45-N49 PolarHBondContact O-OD1 3.24Å
50R91.4Very high92.3Very high71 Ų7140.8 Ų40.827%0.26820%0.196SC..BIsolated β-bridgetrans-131.3147177.5-67.4-176.665.5177.73.8111G45 D54 F55 D58 P488G45-R50 PolarHBondContact O-N 3.12Å; R50-D54 VanDerWaalsContact NH2-C 3.27Å; R50-D54 VanDerWaalsContact NH2-CB 3.3Å; R50-D54 PolarHBondContact NH2-O 2.99Å; R50-F55 HydrophobicContact CB-CE1 4.25Å; R50-F55 HydrophobicContact CB-CE2 3.69Å; R50-F55 HydrophobicContact CB-CZ 3.49Å; R50-F55 VanDerWaalsContact CB-CZ 3.49Å; R50-F55 HydrophobicContact CG-CZ 4.27Å; R50-D58 IonicContact CZ-OD2 2.7Å; R50-D58 IonicContact NH1-OD2 3.49Å; R50-D58 IonicContact NH2-OD2 3.94Å; R50-D58 PolarHBondContact NH2-OD2 3.04Å; R50-P488 WeakPolarHBondContact O-CB 3.35Å
51V92.7Very high92.7Very high15 Ų1540.8 Ų40.89%0.09120%0.199CC..  trans-90.3164.4173.9-68.10000111.2H53 D54 F55 S487V51-H53 HydrophobicContact CG2-CB 3.99Å; V51-H53 PolarHBondContact O-N 3.21Å; V51-D54 VanDerWaalsContact CG2-OD1 3.28Å; V51-D54 WeakPolarHBondContact CG2-OD1 3.33Å; V51-D54 WeakPolarHBondContact CG2-OD2 3.42Å; V51-D54 PolarHBondContact N-OD2 3.48Å; V51-D54 PolarHBondContact O-N 3.41Å; V51-F55 WeakPolarHBondContact O-CD2 3.5Å; V51-S487 WeakPolarHBondContact CG1-O 3.46Å
52M92.6Very high92.9Very high25 Ų2546.3 Ų46.312%0.12322%0.223CC..Hα-helixtrans-59.7-30.4176.9-78.6-170.5-73.900113.4M43 F46 F55 F56 P377 I491M43-M52 HydrophobicContact CE-CG 4.02Å; F46-M52 HydrophobicContact CD2-CG 4.21Å; F46-M52 HydrophobicContact CE2-CG 3.74Å; F46-M52 HydrophobicContact CE2-SD 4.03Å; M52-F55 PolarHBondContact O-N 2.47Å; M52-F56 HydrophobicContact CB-CD2 4.4Å; M52-F56 HydrophobicContact CB-CE2 3.95Å; M52-F56 HydrophobicContact CG-CE2 4.43Å; M52-F56 WeakPolarHBondContact O-CD2 3.37Å; M52-F56 WeakPolarHBondContact O-CG 3.24Å; M52-F56 PolarHBondContact O-N 2.93Å; M52-P377 HydrophobicContact CB-CB 4.37Å; M52-P377 HydrophobicContact CB-CG 3.59Å; M52-P377 HydrophobicContact CE-CG 4.25Å; M52-P377 HydrophobicContact SD-CG 4.49Å; M52-I491 WeakPolarHBondContact CE-O 3.35Å
53H94.5Very high93.1Very high17 Ų1746.3 Ų46.38%0.07922%0.222CC..Hα-helixtrans-56.9-52.6175.5-80.863.7000111.4V51 F55 F56 Y57 T374 C408V51-H53 HydrophobicContact CG2-CB 3.99Å; V51-H53 PolarHBondContact O-N 3.21Å; H53-F55 VanDerWaalsContact C-N 3.26Å; H53-F55 PolarHBondContact O-N 2.83Å; H53-F56 PolarHBondContact O-N 3Å; H53-Y57 WeakPolarHBondContact O-CB 3.27Å; H53-Y57 PolarHBondContact O-N 3.48Å; H53-T374 PolarHBondContact CE1-O 3.48Å; H53-T374 PolarHBondContact NE2-O 3.45Å; H53-T374 VanDerWaalsContact NE2-O 3.12Å; H53-C408 WeakPolarHBondContact CD2-CB 3.31Å; H53-C408 WeakPolarHBondContact NE2-CB 3.25Å
54D94.8Very high93.3Very high59 Ų5948.1 Ų48.132%0.31623%0.228SC..Hα-helixtrans-55.9-43.3-177-43.6-27.5000111.3R50 V51 D58R50-D54 VanDerWaalsContact NH2-C 3.27Å; R50-D54 VanDerWaalsContact NH2-CB 3.3Å; R50-D54 PolarHBondContact NH2-O 2.99Å; V51-D54 VanDerWaalsContact CG2-OD1 3.28Å; V51-D54 WeakPolarHBondContact CG2-OD1 3.33Å; V51-D54 WeakPolarHBondContact CG2-OD2 3.42Å; V51-D54 PolarHBondContact N-OD2 3.48Å; V51-D54 PolarHBondContact O-N 3.41Å; D54-D58 VanDerWaalsContact O-CB 3.28Å; D54-D58 WeakPolarHBondContact O-CB 3.49Å; D54-D58 PolarHBondContact O-N 2.91Å
55F95.3Very high93.4Very high7 Ų751.6 Ų51.63%0.03124%0.237CC..Hα-helixtrans-63.4-47.6-179.6-66.6-61.9000112.2M43 V44 F46 R50 V51 M52 H53 Y59M43-F55 VanDerWaalsContact C-CE1 3.4Å; M43-F55 HydrophobicContact CB-CD1 4.38Å; M43-F55 HydrophobicContact CB-CD2 4.4Å; M43-F55 HydrophobicContact CB-CE1 4.42Å; M43-F55 HydrophobicContact CB-CE2 4.45Å; M43-F55 HydrophobicContact CB-CG 4.37Å; M43-F55 HydrophobicContact CB-CZ 4.45Å; M43-F55 HydrophobicContact CE-CD2 4.11Å; M43-F55 HydrophobicContact CG-CG 4.48Å; V44-F55 WeakPolarHBondContact O-CE1 3.43Å; V44-F55 VanDerWaalsContact O-CZ 3.31Å; V44-F55 WeakPolarHBondContact O-CZ 3.36Å; F46-F55 HydrophobicContact CB-CE2 4.07Å; F46-F55 HydrophobicContact CB-CZ 4.35Å; F46-F55 HydrophobicContact CD2-CE2 4.45Å; R50-F55 HydrophobicContact CB-CE1 4.25Å; R50-F55 HydrophobicContact CB-CE2 3.69Å; R50-F55 HydrophobicContact CB-CZ 3.49Å; R50-F55 VanDerWaalsContact CB-CZ 3.49Å; R50-F55 HydrophobicContact CG-CZ 4.27Å; V51-F55 WeakPolarHBondContact O-CD2 3.5Å; M52-F55 PolarHBondContact O-N 2.47Å; H53-F55 VanDerWaalsContact C-N 3.26Å; H53-F55 PolarHBondContact O-N 2.83Å; F55-Y59 WeakPolarHBondContact O-CB 3.38Å; F55-Y59 PolarHBondContact O-N 3.34Å; F55-Y59 VanDerWaalsContact O-N 3.16Å
56F96.5Very high93.7Very high0 Ų053.3 Ų53.30%025%0.248CC..Hα-helixtrans-76.5-35.9-176.1-58.6-38.7000112.3M43 M52 H53 Y60 F73 F75 F82 P377 H378 I404 P406M43-F56 HydrophobicContact CE-CZ 4.41Å; M52-F56 HydrophobicContact CB-CD2 4.4Å; M52-F56 HydrophobicContact CB-CE2 3.95Å; M52-F56 HydrophobicContact CG-CE2 4.43Å; M52-F56 WeakPolarHBondContact O-CD2 3.37Å; M52-F56 WeakPolarHBondContact O-CG 3.24Å; M52-F56 PolarHBondContact O-N 2.93Å; H53-F56 PolarHBondContact O-N 3Å; F56-Y60 WeakPolarHBondContact O-CB 3.4Å; F56-Y60 PolarHBondContact O-N 3.38Å; F56-F73 HydrophobicContact CD1-CZ 4.27Å; F56-F73 HydrophobicContact CE1-CE1 4.19Å; F56-F73 AromaticContact CE1-CZ 3.88Å; F56-F73 HydrophobicContact CE1-CZ 3.88Å; F56-F75 HydrophobicContact CZ-CE2 4.21Å; F56-F82 HydrophobicContact CB-CE2 4.15Å; F56-F82 HydrophobicContact CB-CZ 4.23Å; F56-F82 HydrophobicContact CD1-CD2 4.47Å; F56-F82 AromaticContact CD1-CE2 3.63Å; F56-F82 HydrophobicContact CD1-CE2 3.63Å; F56-F82 HydrophobicContact CD1-CZ 4.49Å; F56-F82 HydrophobicContact CE1-CE2 4.41Å; F56-F82 HydrophobicContact CG-CE2 4.18Å; F56-P377 HydrophobicContact CD2-CB 4.06Å; F56-P377 HydrophobicContact CE2-CB 4.33Å; F56-P377 HydrophobicContact CE2-CG 4.32Å; F56-H378 HydrophobicContact CD2-CB 3.91Å; F56-H378 HydrophobicContact CE2-CB 3.64Å; F56-H378 AromaticContact CE2-CE1 3.87Å; F56-H378 AromaticContact CE2-CG 3.39Å; F56-H378 AromaticContact CE2-ND1 3.2Å; F56-H378 WeakPolarHBondContact CE2-ND1 3.45Å; F56-H378 HydrophobicContact CZ-CB 4.18Å; F56-H378 AromaticContact CZ-CD2 3.99Å; F56-H378 AromaticContact CZ-CE1 3.98Å; F56-H378 AromaticContact CZ-CG 3.7Å; F56-H378 AromaticContact CZ-ND1 3.71Å; F56-I404 HydrophobicContact CE1-CG2 4.21Å; F56-P406 HydrophobicContact CB-CB 4.02Å
57Y96.5Very high94.1Very high71 Ų7155.4 Ų55.428%0.27828%0.276SS..Hα-helixtrans-63.9-51.4175.9-176.3-105.5000111.6H53 Y59 Y60 N61 A409 R412H53-Y57 WeakPolarHBondContact O-CB 3.27Å; H53-Y57 PolarHBondContact O-N 3.48Å; Y57-Y59 VanDerWaalsContact C-N 3.34Å; Y57-Y59 PolarHBondContact O-N 2.86Å; Y57-Y60 PolarHBondContact O-N 2.91Å; Y57-N61 WeakPolarHBondContact CE1-ND2 3.38Å; Y57-N61 WeakPolarHBondContact CE2-ND2 3.4Å; Y57-N61 WeakPolarHBondContact O-CB 3.5Å; Y57-N61 PolarHBondContact O-N 3.24Å; Y57-N61 PolarHBondContact OH-ND2 3.41Å; Y57-A409 HydrophobicContact CD2-CB 4.44Å; Y57-R412 HydrophobicContact CD2-CB 4.03Å; Y57-R412 HydrophobicContact CE2-CB 3.53Å
58D96.8Very high94.7Very high83 Ų8357.5 Ų57.544%0.44429%0.286SS..Hα-helixtrans-61.5-44178.7-69-7.3000111.6R50 D54 K62R50-D58 IonicContact CZ-OD2 2.7Å; R50-D58 IonicContact NH1-OD2 3.49Å; R50-D58 IonicContact NH2-OD2 3.94Å; R50-D58 PolarHBondContact NH2-OD2 3.04Å; D54-D58 VanDerWaalsContact O-CB 3.28Å; D54-D58 WeakPolarHBondContact O-CB 3.49Å; D54-D58 PolarHBondContact O-N 2.91Å; D58-K62 WeakPolarHBondContact O-CB 3.48Å; D58-K62 PolarHBondContact O-N 3.3Å; D58-K62 VanDerWaalsContact O-N 3.1Å
59Y97.5Very high95.3Very high12 Ų1250.1 Ų50.15%0.04725%0.254CS..Hα-helixtrans-65.8-42.5-179.9-150.7-98.9000111.4D34 N42 F55 Y57 Y63 V71 G72 F73 F82D34-Y59 HydrophobicContact CB-CE2 3.94Å; D34-Y59 PolarHBondContact N-OH 3.4Å; N42-Y59 HydrophobicContact CB-CE2 4.16Å; F55-Y59 WeakPolarHBondContact O-CB 3.38Å; F55-Y59 PolarHBondContact O-N 3.34Å; F55-Y59 VanDerWaalsContact O-N 3.16Å; Y57-Y59 VanDerWaalsContact C-N 3.34Å; Y57-Y59 PolarHBondContact O-N 2.86Å; Y59-Y63 AromaticContact CD1-CD2 3.91Å; Y59-Y63 HydrophobicContact CD1-CD2 3.91Å; Y59-Y63 HydrophobicContact CD1-CE2 4.17Å; Y59-Y63 HydrophobicContact CD2-CE2 4.34Å; Y59-Y63 AromaticContact CE1-CD2 3.8Å; Y59-Y63 HydrophobicContact CE1-CD2 3.8Å; Y59-Y63 AromaticContact CE1-CE2 3.73Å; Y59-Y63 HydrophobicContact CE1-CE2 3.73Å; Y59-Y63 AromaticContact CE2-CE2 3.9Å; Y59-Y63 HydrophobicContact CE2-CE2 3.9Å; Y59-Y63 HydrophobicContact CG-CD2 4.36Å; Y59-Y63 HydrophobicContact CG-CE2 4.46Å; Y59-Y63 AromaticContact CZ-CE2 3.58Å; Y59-Y63 VanDerWaalsContact O-CD2 3.3Å; Y59-Y63 WeakPolarHBondContact O-CD2 3.48Å; Y59-Y63 PolarHBondContact O-N 3.44Å; Y59-V71 HydrophobicContact CD1-CG2 4.15Å; Y59-V71 HydrophobicContact CE1-CG2 3.67Å; Y59-G72 PolarHBondContact OH-O 2.96Å; Y59-F73 AromaticContact CD1-CD2 3.77Å; Y59-F73 HydrophobicContact CD1-CD2 3.77Å; Y59-F73 HydrophobicContact CD1-CE2 4.39Å; Y59-F73 HydrophobicContact CD2-CD2 4.12Å; Y59-F73 HydrophobicContact CD2-CE2 4.24Å; Y59-F73 HydrophobicContact CE1-CB 4.22Å; Y59-F73 AromaticContact CE1-CD2 3.7Å; Y59-F73 HydrophobicContact CE1-CD2 3.7Å; Y59-F73 HydrophobicContact CE1-CG 4.46Å; Y59-F73 HydrophobicContact CE2-CD2 4.08Å; Y59-F73 AromaticContact CG-CD2 3.97Å; Y59-F73 HydrophobicContact CG-CD2 3.97Å; Y59-F73 HydrophobicContact CG-CE2 4.17Å; Y59-F73 AromaticContact CZ-CD2 3.86Å; Y59-F82 AromaticContact CD1-CD1 3.91Å; Y59-F82 HydrophobicContact CD1-CD1 3.91Å; Y59-F82 HydrophobicContact CD1-CD2 4.38Å; Y59-F82 HydrophobicContact CD1-CE1 4.09Å; Y59-F82 HydrophobicContact CD1-CG 4.04Å; Y59-F82 HydrophobicContact CD1-CZ 4.41Å; Y59-F82 HydrophobicContact CE1-CG 4.47Å
60Y98.1Very high95.7Very high9 Ų944.7 Ų44.74%0.03523%0.225CC..Hα-helixtrans-60.7-52.7175.6179.9-104000111.6F56 Y57 K62 Y63 R64 F82 V84 P406 A409 Y410 D413F56-Y60 WeakPolarHBondContact O-CB 3.4Å; F56-Y60 PolarHBondContact O-N 3.38Å; Y57-Y60 PolarHBondContact O-N 2.91Å; Y60-K62 PolarHBondContact O-N 2.97Å; Y60-Y63 CarbonylContact O-C 3.46Å; Y60-Y63 PolarHBondContact O-N 3.49Å; Y60-R64 HydrophobicContact CD1-CB 4.22Å; Y60-R64 HydrophobicContact CD2-CB 4.4Å; Y60-R64 HydrophobicContact CE1-CB 3.83Å; Y60-R64 HydrophobicContact CE1-CG 4.27Å; Y60-R64 HydrophobicContact CE2-CB 4Å; Y60-R64 HydrophobicContact CG-CB 4.49Å; Y60-R64 WeakPolarHBondContact O-CB 3.47Å; Y60-R64 PolarHBondContact O-N 3.32Å; Y60-F82 HydrophobicContact CD2-CE1 4.3Å; Y60-V84 HydrophobicContact CD2-CG1 4.06Å; Y60-V84 HydrophobicContact CE2-CB 4.46Å; Y60-V84 HydrophobicContact CE2-CG1 3.78Å; Y60-V84 WeakPolarHBondContact CE2-O 3.38Å; Y60-P406 HydrophobicContact CD2-CG 3.98Å; Y60-A409 VanDerWaalsContact CB-CB 3.46Å; Y60-A409 HydrophobicContact CD1-CB 3.65Å; Y60-A409 HydrophobicContact CD2-CB 4.3Å; Y60-A409 HydrophobicContact CE1-CB 4.48Å; Y60-A409 HydrophobicContact CG-CB 3.53Å; Y60-Y410 HydrophobicContact CD2-CD1 4.32Å; Y60-Y410 HydrophobicContact CD2-CE1 4.06Å; Y60-Y410 AromaticContact CE2-CD1 3.74Å; Y60-Y410 HydrophobicContact CE2-CD1 3.74Å; Y60-Y410 AromaticContact CE2-CE1 3.47Å; Y60-Y410 HydrophobicContact CE2-CE1 3.47Å; Y60-Y410 VanDerWaalsContact CE2-CE1 3.47Å; Y60-Y410 AromaticContact CZ-CD1 3.86Å; Y60-D413 HydrophobicContact CE1-CB 4.15Å; Y60-D413 WeakPolarHBondContact CE1-OD2 3.35Å; Y60-D413 PolarHBondContact OH-OD2 3.22Å
61N97.3Very high96.1Very high56 Ų5641.3 Ų41.330%0.29921%0.212SC..Hα-helixtrans-60.6-33.9-177.8-77.7-22000113.2Y57 Y63Y57-N61 WeakPolarHBondContact CE1-ND2 3.38Å; Y57-N61 WeakPolarHBondContact CE2-ND2 3.4Å; Y57-N61 WeakPolarHBondContact O-CB 3.5Å; Y57-N61 PolarHBondContact O-N 3.24Å; Y57-N61 PolarHBondContact OH-ND2 3.41Å; N61-Y63 VanDerWaalsContact C-N 3.33Å; N61-Y63 PolarHBondContact O-N 2.98Å
62K97.6Very high96.3Very high118 Ų11840.6 Ų40.651%0.51321%0.208SC..Hα-helixtrans-64.1-36.4174.4179.7172.8174.9174.10113.2D34 D58 Y60D34-K62 WeakPolarHBondContact OD1-CE 3.25Å; D34-K62 IonicContact OD1-NZ 3.12Å; D34-K62 PolarHBondContact OD1-NZ 3.45Å; D34-K62 IonicContact OD2-NZ 2.71Å; D34-K62 PolarHBondContact OD2-NZ 2.92Å; D58-K62 WeakPolarHBondContact O-CB 3.48Å; D58-K62 PolarHBondContact O-N 3.3Å; D58-K62 VanDerWaalsContact O-N 3.1Å; Y60-K62 PolarHBondContact O-N 2.97Å
63Y97.8Very high96.5Very high23 Ų2339.4 Ų39.49%0.0920%0.202CC..Hα-helixtrans-110.7-10.9-170.6-70.8-70.2000115.1P32 H33 D34 Y59 Y60 N61 K65 S66 V71P32-Y63 HydrophobicContact CB-CD1 4.4Å; P32-Y63 HydrophobicContact CB-CE1 4.01Å; H33-Y63 PolarHBondContact O-OH 3.19Å; D34-Y63 PolarHBondContact N-OH 3.07Å; D34-Y63 PolarHBondContact OD1-OH 2.78Å; D34-Y63 VanDerWaalsContact OD1-OH 3.09Å; Y59-Y63 AromaticContact CD1-CD2 3.91Å; Y59-Y63 HydrophobicContact CD1-CD2 3.91Å; Y59-Y63 HydrophobicContact CD1-CE2 4.17Å; Y59-Y63 HydrophobicContact CD2-CE2 4.34Å; Y59-Y63 AromaticContact CE1-CD2 3.8Å; Y59-Y63 HydrophobicContact CE1-CD2 3.8Å; Y59-Y63 AromaticContact CE1-CE2 3.73Å; Y59-Y63 HydrophobicContact CE1-CE2 3.73Å; Y59-Y63 AromaticContact CE2-CE2 3.9Å; Y59-Y63 HydrophobicContact CE2-CE2 3.9Å; Y59-Y63 HydrophobicContact CG-CD2 4.36Å; Y59-Y63 HydrophobicContact CG-CE2 4.46Å; Y59-Y63 AromaticContact CZ-CE2 3.58Å; Y59-Y63 VanDerWaalsContact O-CD2 3.3Å; Y59-Y63 WeakPolarHBondContact O-CD2 3.48Å; Y59-Y63 PolarHBondContact O-N 3.44Å; Y60-Y63 CarbonylContact O-C 3.46Å; Y60-Y63 PolarHBondContact O-N 3.49Å; N61-Y63 VanDerWaalsContact C-N 3.33Å; N61-Y63 PolarHBondContact O-N 2.98Å; Y63-K65 PolarHBondContact O-N 2.7Å; Y63-K65 VanDerWaalsContact O-N 3.13Å; Y63-S66 WeakPolarHBondContact O-CB 3.28Å; Y63-S66 PolarHBondContact O-N 3.49Å; Y63-S66 PolarHBondContact O-OG 2.85Å; Y63-V71 HydrophobicContact CD1-CB 4.44Å; Y63-V71 HydrophobicContact CD1-CG1 3.75Å; Y63-V71 HydrophobicContact CD2-CB 4.49Å; Y63-V71 HydrophobicContact CD2-CG2 3.93Å; Y63-V71 HydrophobicContact CE1-CG1 4.45Å; Y63-V71 HydrophobicContact CG-CB 4.23Å; Y63-V71 HydrophobicContact CG-CG1 3.79Å; Y63-V71 HydrophobicContact CG-CG2 3.95Å
64R95.8Very high96.6Very high37 Ų3738.6 Ų38.614%0.1420%0.198CC..THydrogen-bonded Turntrans-58.2-28.9-176.868.2172.6-145.7163.822.5115.1Y60 V84 D413 E414 D415Y60-R64 HydrophobicContact CD1-CB 4.22Å; Y60-R64 HydrophobicContact CD2-CB 4.4Å; Y60-R64 HydrophobicContact CE1-CB 3.83Å; Y60-R64 HydrophobicContact CE1-CG 4.27Å; Y60-R64 HydrophobicContact CE2-CB 4Å; Y60-R64 HydrophobicContact CG-CB 4.49Å; Y60-R64 WeakPolarHBondContact O-CB 3.47Å; Y60-R64 PolarHBondContact O-N 3.32Å; R64-V84 HydrophobicContact CB-CG1 3.92Å; R64-D413 IonicContact CZ-OD1 2.67Å; R64-D413 IonicContact NH1-OD1 2.62Å; R64-D413 PolarHBondContact NH1-OD1 2.77Å; R64-D413 IonicContact NH1-OD2 3.83Å; R64-D413 IonicContact NH2-OD1 3.85Å; R64-E414 IonicContact CZ-OE1 3.13Å; R64-E414 IonicContact NH2-OE1 3.62Å; R64-E414 PolarHBondContact NH2-OE1 3.47Å; R64-D415 IonicContact CZ-OD2 2.72Å; R64-D415 IonicContact NE-OD2 3.84Å; R64-D415 IonicContact NH1-OD2 2.66Å; R64-D415 IonicContact NH2-OD1 3.75Å; R64-D415 IonicContact NH2-OD2 3.24Å; R64-D415 PolarHBondContact NH2-OD2 2.75Å
65K94.8Very high96.3Very high152 Ų15237.3 Ų37.366%0.66119%0.19SC*.THydrogen-bonded Turntrans-99.715175.8-64.8178.2-180170.10113.3Y63 G67 E414Y63-K65 PolarHBondContact O-N 2.7Å; Y63-K65 VanDerWaalsContact O-N 3.13Å; K65-G67 VanDerWaalsContact C-N 3.34Å; K65-G67 PolarHBondContact O-N 2.93Å; K65-E414 IonicContact NZ-OE1 3.72Å
66S94.4Very high96Very high43 Ų4337.1 Ų37.130%0.30119%0.189SC..SBendtrans-77.4-15.4-177.468.20000114.6Y63 F68Y63-S66 WeakPolarHBondContact O-CB 3.28Å; Y63-S66 PolarHBondContact O-N 3.49Å; Y63-S66 PolarHBondContact O-OG 2.85Å; S66-F68 WeakPolarHBondContact O-CD2 3.49Å; S66-F68 PolarHBondContact O-N 3.46Å; S66-F68 PolarHBondContact OG-N 2.94Å
67G93.6Very high95.5Very high65 Ų6539 Ų3967%0.6720%0.198SC*.SBendtrans782.6-173.400000114.7K65K65-G67 VanDerWaalsContact C-N 3.34Å; K65-G67 PolarHBondContact O-N 2.93Å
68F96.7Very high95.1Very high73 Ų7337.8 Ų37.832%0.3219%0.194SC..  trans-95.9135.5173.3-72.1-102.4000110.7P32 S66 F70 V71 L395P32-F68 VanDerWaalsContact CD-CE1 3.5Å; P32-F68 HydrophobicContact CG-CD1 3.94Å; P32-F68 HydrophobicContact CG-CD2 3.62Å; P32-F68 HydrophobicContact CG-CE1 3.85Å; P32-F68 HydrophobicContact CG-CE2 3.52Å; P32-F68 HydrophobicContact CG-CG 3.84Å; P32-F68 HydrophobicContact CG-CZ 3.64Å; S66-F68 WeakPolarHBondContact O-CD2 3.49Å; S66-F68 PolarHBondContact O-N 3.46Å; S66-F68 PolarHBondContact OG-N 2.94Å; F68-F70 VanDerWaalsContact C-N 3.26Å; F68-F70 WeakPolarHBondContact CB-O 3.4Å; F68-F70 PolarHBondContact O-N 3.23Å; F68-V71 HydrophobicContact CB-CG1 4.35Å; F68-L395 HydrophobicContact CD1-CD1 3.87Å; F68-L395 HydrophobicContact CD1-CD2 4.23Å; F68-L395 HydrophobicContact CE1-CD1 4.49Å; F68-L395 HydrophobicContact CE1-CD2 4.25Å
69P97.3Very high95Very high3 Ų334.8 Ų34.82%0.01918%0.179CC..SBendtrans-71.5-24.1179.831.2-37.7000112.5V84 D85 L88 V389 H392 L395P69-V84 PolarHBondContact O-N 2.92Å; P69-D85 HydrophobicContact CB-CB 3.97Å; P69-D85 PolarHBondContact O-N 3.09Å; P69-L88 HydrophobicContact CB-CB 4.36Å; P69-L88 HydrophobicContact CB-CD2 3.84Å; P69-L88 HydrophobicContact CG-CD2 4.4Å; P69-V389 HydrophobicContact CB-CG1 4.18Å; P69-V389 HydrophobicContact CG-CG1 3.73Å; P69-H392 HydrophobicContact CG-CB 4.49Å; P69-L395 HydrophobicContact CG-CD1 3.79Å
70F98.4Very high95Very high0 Ų034.2 Ų34.20%018%0.177CC..EExtended strand (participates in β ladder)trans-146157.6168.676.2-91.6000110.6W26 V31 F68 A81 F82 I83 L88 V389 L395 I397W26-F70 HydrophobicContact CH2-CE2 4.06Å; W26-F70 AromaticContact CZ3-CE2 3.65Å; W26-F70 HydrophobicContact CZ3-CE2 3.65Å; W26-F70 HydrophobicContact CZ3-CZ 4.44Å; V31-F70 HydrophobicContact CG1-CD2 4.18Å; V31-F70 HydrophobicContact CG1-CE2 3.79Å; V31-F70 HydrophobicContact CG2-CE2 4.09Å; V31-F70 HydrophobicContact CG2-CZ 4.26Å; F68-F70 VanDerWaalsContact C-N 3.26Å; F68-F70 WeakPolarHBondContact CB-O 3.4Å; F68-F70 PolarHBondContact O-N 3.23Å; F70-A81 HydrophobicContact CD2-CB 3.78Å; F70-A81 HydrophobicContact CE2-CB 4.17Å; F70-A81 HydrophobicContact CG-CB 4.3Å; F70-F82 CarbonylContact C-O 3.58Å; F70-F82 VanDerWaalsContact CA-O 3.24Å; F70-F82 WeakPolarHBondContact CA-O 3.38Å; F70-F82 WeakPolarHBondContact CB-O 3.41Å; F70-I83 HydrophobicContact CB-CD1 3.71Å; F70-L88 HydrophobicContact CB-CD2 4.12Å; F70-L88 HydrophobicContact CD1-CD2 4Å; F70-V389 HydrophobicContact CD1-CG2 3.92Å; F70-V389 HydrophobicContact CE1-CG2 3.65Å; F70-L395 HydrophobicContact CE1-CB 3.88Å; F70-L395 HydrophobicContact CZ-CB 4.34Å; F70-I397 HydrophobicContact CD1-CD1 4.35Å; F70-I397 HydrophobicContact CD1-CG1 4.2Å; F70-I397 HydrophobicContact CE1-CD1 4.44Å; F70-I397 HydrophobicContact CE1-CG1 3.82Å; F70-I397 HydrophobicContact CZ-CG1 4.04Å
71V98.4Very high95Very high0 Ų033.8 Ų33.80%018%0.175CC..EExtended strand (participates in β ladder)trans-122.9160.7173.7-67.20000110.6P32 Y59 Y63 F68 F82 V84P32-V71 HydrophobicContact CB-CG1 4.15Å; P32-V71 WeakPolarHBondContact O-CB 3.48Å; Y59-V71 HydrophobicContact CD1-CG2 4.15Å; Y59-V71 HydrophobicContact CE1-CG2 3.67Å; Y63-V71 HydrophobicContact CD1-CB 4.44Å; Y63-V71 HydrophobicContact CD1-CG1 3.75Å; Y63-V71 HydrophobicContact CD2-CB 4.49Å; Y63-V71 HydrophobicContact CD2-CG2 3.93Å; Y63-V71 HydrophobicContact CE1-CG1 4.45Å; Y63-V71 HydrophobicContact CG-CB 4.23Å; Y63-V71 HydrophobicContact CG-CG1 3.79Å; Y63-V71 HydrophobicContact CG-CG2 3.95Å; F68-V71 HydrophobicContact CB-CG1 4.35Å; V71-F82 HydrophobicContact CG2-CB 4.13Å; V71-F82 HydrophobicContact CG2-CD1 4.02Å; V71-F82 HydrophobicContact CG2-CG 4.49Å; V71-F82 PolarHBondContact N-O 2.89Å; V71-F82 PolarHBondContact O-N 3.06Å; V71-V84 HydrophobicContact CG1-CG2 4.3Å; V71-V84 HydrophobicContact CG2-CG2 3.77Å
72G97.9Very high95.1Very high0 Ų031.1 Ų31.10%016%0.161CC..EExtended strand (participates in β ladder)trans-74.7136.7177.200000110.5W26 V31 P32 H33 Y59W26-G72 VanDerWaalsContact CD1-CA 3.45Å; W26-G72 VanDerWaalsContact CE2-CA 3.41Å; W26-G72 VanDerWaalsContact CG-CA 3.48Å; V31-G72 VanDerWaalsContact CG1-N 3.31Å; P32-G72 PolarHBondContact O-N 2.68Å; H33-G72 WeakPolarHBondContact CB-O 3.47Å; Y59-G72 PolarHBondContact OH-O 2.96Å
73F97.5Very high95.1Very high0 Ų025.5 Ų25.50%014%0.136CC..EExtended strand (participates in β ladder)trans-136.9156.4174.7-175.9-92.7000109.7W26 N42 M43 F56 Y59 F75 P79 A80 F82 I404W26-F73 PolarHBondContact NE1-O 2.76Å; W26-F73 VanDerWaalsContact NE1-O 3.1Å; N42-F73 HydrophobicContact CB-CD2 3.78Å; N42-F73 HydrophobicContact CB-CE2 3.53Å; N42-F73 HydrophobicContact CB-CG 4.49Å; N42-F73 HydrophobicContact CB-CZ 4.06Å; M43-F73 HydrophobicContact CG-CE1 4.13Å; M43-F73 HydrophobicContact CG-CZ 3.65Å; M43-F73 HydrophobicContact SD-CE1 4.28Å; M43-F73 HydrophobicContact SD-CZ 4.26Å; F56-F73 HydrophobicContact CD1-CZ 4.27Å; F56-F73 HydrophobicContact CE1-CE1 4.19Å; F56-F73 AromaticContact CE1-CZ 3.88Å; F56-F73 HydrophobicContact CE1-CZ 3.88Å; Y59-F73 AromaticContact CD1-CD2 3.77Å; Y59-F73 HydrophobicContact CD1-CD2 3.77Å; Y59-F73 HydrophobicContact CD1-CE2 4.39Å; Y59-F73 HydrophobicContact CD2-CD2 4.12Å; Y59-F73 HydrophobicContact CD2-CE2 4.24Å; Y59-F73 HydrophobicContact CE1-CB 4.22Å; Y59-F73 AromaticContact CE1-CD2 3.7Å; Y59-F73 HydrophobicContact CE1-CD2 3.7Å; Y59-F73 HydrophobicContact CE1-CG 4.46Å; Y59-F73 HydrophobicContact CE2-CD2 4.08Å; Y59-F73 AromaticContact CG-CD2 3.97Å; Y59-F73 HydrophobicContact CG-CD2 3.97Å; Y59-F73 HydrophobicContact CG-CE2 4.17Å; Y59-F73 AromaticContact CZ-CD2 3.86Å; F73-F75 HydrophobicContact CD1-CB 4.29Å; F73-F75 HydrophobicContact CE1-CB 4.03Å; F73-F75 HydrophobicContact CE1-CD2 4.16Å; F73-P79 CarbonylContact O-C 3.58Å; F73-P79 WeakPolarHBondContact O-CA 3.28Å; F73-A80 HydrophobicContact CD1-CB 4.48Å; F73-A80 PolarHBondContact N-O 3.44Å; F73-A80 PolarHBondContact O-N 3.21Å; F73-A80 VanDerWaalsContact O-O 3.12Å; F73-F82 HydrophobicContact CB-CB 3.67Å; F73-F82 HydrophobicContact CB-CD2 4.42Å; F73-F82 HydrophobicContact CB-CG 4.4Å; F73-F82 HydrophobicContact CD2-CD2 4.17Å; F73-F82 HydrophobicContact CG-CB 4.39Å; F73-F82 HydrophobicContact CG-CD2 4.24Å; F73-I404 HydrophobicContact CD1-CD1 3.59Å; F73-I404 HydrophobicContact CE1-CD1 3.85Å; F73-I404 HydrophobicContact CG-CD1 4.5Å
74Y95.1Very high95.1Very high0 Ų024.7 Ų24.70%013%0.134CC..EExtended strand (participates in β ladder)trans-121.9104.2174.5-73.5-87.4000109N22 F23 Y25 W26 P36 N42 L76 K78 P79N22-Y74 VanDerWaalsContact O-CE1 3.3Å; N22-Y74 WeakPolarHBondContact O-CE1 3.34Å; N22-Y74 PolarHBondContact O-OH 3.38Å; F23-Y74 PolarHBondContact O-OH 2.8Å; Y25-Y74 WeakPolarHBondContact CB-OH 3.25Å; Y25-Y74 PolarHBondContact N-OH 2.97Å; Y25-Y74 VanDerWaalsContact N-OH 3.15Å; W26-Y74 AromaticContact CD1-CE2 3.43Å; W26-Y74 VanDerWaalsContact CD1-CE2 3.43Å; W26-Y74 AromaticContact CD1-CZ 3.7Å; W26-Y74 HydrophobicContact CG-CE2 4.48Å; P36-Y74 HydrophobicContact CB-CD1 4.34Å; P36-Y74 HydrophobicContact CB-CD2 3.54Å; P36-Y74 HydrophobicContact CB-CE2 4.12Å; P36-Y74 HydrophobicContact CB-CG 3.66Å; P36-Y74 HydrophobicContact CG-CD1 4.43Å; P36-Y74 HydrophobicContact CG-CD2 3.58Å; P36-Y74 HydrophobicContact CG-CE1 4.48Å; P36-Y74 HydrophobicContact CG-CE2 3.61Å; P36-Y74 HydrophobicContact CG-CG 4.01Å; N42-Y74 PolarHBondContact N-O 3.37Å; N42-Y74 WeakPolarHBondContact OD1-CB 3.46Å; N42-Y74 PolarHBondContact OD1-N 3.23Å; Y74-L76 PolarHBondContact O-N 3.06Å; Y74-K78 WeakPolarHBondContact CA-O 3.45Å; Y74-P79 HydrophobicContact CD1-CB 4.3Å; Y74-P79 HydrophobicContact CE1-CB 3.92Å
75F90Very high95.2Very high32 Ų3225.7 Ų25.714%0.1414%0.142CC..EExtended strand (participates in β ladder)trans-81101.1170.1-164.7-75.5000107.7M43 F56 F73 H77 K78 I404M43-F75 HydrophobicContact CE-CD2 4.4Å; M43-F75 HydrophobicContact CE-CE2 3.87Å; M43-F75 HydrophobicContact CE-CZ 4.2Å; M43-F75 HydrophobicContact SD-CD1 4.29Å; M43-F75 HydrophobicContact SD-CD2 3.53Å; M43-F75 VanDerWaalsContact SD-CD2 3.53Å; M43-F75 HydrophobicContact SD-CE1 4.3Å; M43-F75 HydrophobicContact SD-CE2 3.55Å; M43-F75 VanDerWaalsContact SD-CE2 3.55Å; M43-F75 HydrophobicContact SD-CG 3.93Å; M43-F75 HydrophobicContact SD-CZ 3.94Å; F56-F75 HydrophobicContact CZ-CE2 4.21Å; F73-F75 HydrophobicContact CD1-CB 4.29Å; F73-F75 HydrophobicContact CE1-CB 4.03Å; F73-F75 HydrophobicContact CE1-CD2 4.16Å; F75-H77 PolarHBondContact O-N 2.65Å; F75-K78 PolarHBondContact N-O 3.41Å; F75-K78 PolarHBondContact O-N 3.5Å; F75-I404 HydrophobicContact CB-CD1 4.27Å; F75-I404 HydrophobicContact CD2-CD1 4Å
76L87.6Confident95.3Very high3 Ų319.8 Ų19.82%0.01612%0.119CC..THydrogen-bonded Turntrans53.4-120.3-162.4-54.2173.4000109G41 F46 Y74 M225G41-L76 WeakPolarHBondContact CA-O 3.38Å; G41-L76 PolarHBondContact N-O 3.15Å; F46-L76 HydrophobicContact CD1-CD2 4.41Å; Y74-L76 PolarHBondContact O-N 3.06Å; L76-M225 HydrophobicContact CD1-CB 3.95Å; L76-M225 HydrophobicContact CD1-CG 3.96Å; L76-M225 HydrophobicContact CD2-SD 4.18Å
77H86.3Confident95.4Very high39 Ų3921.3 Ų21.318%0.18112%0.121CC..THydrogen-bonded Turntrans-94.3-0.2174.460-105.7000114.3N22 F23 F75 P79 S229 F230N22-H77 PolarHBondContact ND2-O 2.85Å; F23-H77 HydrophobicContact CE2-CB 3.81Å; F23-H77 HydrophobicContact CZ-CB 4.12Å; F75-H77 PolarHBondContact O-N 2.65Å; H77-P79 WeakPolarHBondContact O-CD 3.18Å; H77-S229 WeakPolarHBondContact CE1-CB 3.42Å; H77-S229 PolarHBondContact CE1-OG 2.88Å; H77-S229 PolarHBondContact ND1-OG 2.84Å; H77-S229 WeakPolarHBondContact NE2-CB 3.49Å; H77-S229 PolarHBondContact NE2-OG 3.48Å; H77-F230 AromaticContact CD2-CE1 3.93Å; H77-F230 AromaticContact CD2-CZ 3.63Å; H77-F230 AromaticContact CE1-CD2 3.55Å; H77-F230 AromaticContact CE1-CE2 3.02Å; H77-F230 WeakPolarHBondContact CE1-CE2 3.48Å; H77-F230 AromaticContact CE1-CZ 3.4Å; H77-F230 WeakPolarHBondContact CE1-CZ 3.24Å; H77-F230 AromaticContact NE2-CD1 3.76Å; H77-F230 AromaticContact NE2-CD2 3.47Å; H77-F230 WeakPolarHBondContact NE2-CD2 3.35Å; H77-F230 AromaticContact NE2-CE1 3.32Å; H77-F230 VanDerWaalsContact NE2-CE1 3.32Å; H77-F230 WeakPolarHBondContact NE2-CE1 3.34Å; H77-F230 AromaticContact NE2-CE2 3.03Å; H77-F230 WeakPolarHBondContact NE2-CE2 3.45Å; H77-F230 AromaticContact NE2-CG 3.84Å; H77-F230 AromaticContact NE2-CZ 2.95Å; H77-F230 WeakPolarHBondContact NE2-CZ 3.47Å
78K88.7Confident95.7Very high46 Ų4618.3 Ų18.320%0.29%0.09CC..EExtended strand (participates in β ladder)trans-87.9120.7-176.6-169.2177173.5-164.30109.8Y74 F75 A80Y74-K78 WeakPolarHBondContact CA-O 3.45Å; F75-K78 PolarHBondContact N-O 3.41Å; F75-K78 PolarHBondContact O-N 3.5Å; K78-A80 PolarHBondContact O-N 2.86Å
79P94.6Very high95.8Very high19 Ų1914.9 Ų14.912%0.1238%0.075CC..EExtended strand (participates in β ladder)trans-64.5137.1173.426.8-32.9000110.1N22 Y25 W26 F73 Y74 H77N22-P79 WeakPolarHBondContact OD1-CD 3.24Å; Y25-P79 HydrophobicContact CD1-CB 3.73Å; Y25-P79 HydrophobicContact CD1-CG 4.28Å; Y25-P79 HydrophobicContact CD2-CG 4.4Å; Y25-P79 HydrophobicContact CE1-CB 4.25Å; Y25-P79 HydrophobicContact CG-CB 4.01Å; Y25-P79 HydrophobicContact CG-CG 4.15Å; W26-P79 HydrophobicContact CZ2-CB 4.31Å; F73-P79 CarbonylContact O-C 3.58Å; F73-P79 WeakPolarHBondContact O-CA 3.28Å; Y74-P79 HydrophobicContact CD1-CB 4.3Å; Y74-P79 HydrophobicContact CE1-CB 3.92Å; H77-P79 WeakPolarHBondContact O-CD 3.18Å
80A97.1Very high95.8Very high0 Ų016.7 Ų16.70%08%0.082CC..EExtended strand (participates in β ladder)trans-138.7137.7179.900000110.6W26 F73 K78 F82 Q402 I404W26-A80 WeakPolarHBondContact CZ2-O 3.37Å; F73-A80 HydrophobicContact CD1-CB 4.48Å; F73-A80 PolarHBondContact N-O 3.44Å; F73-A80 PolarHBondContact O-N 3.21Å; F73-A80 VanDerWaalsContact O-O 3.12Å; K78-A80 PolarHBondContact O-N 2.86Å; A80-F82 PolarHBondContact O-N 3.46Å; A80-Q402 CarbonylContact C-O 3.18Å; A80-Q402 WeakPolarHBondContact CA-O 3.4Å; A80-Q402 HydrophobicContact CB-CB 3.88Å; A80-Q402 HydrophobicContact CB-CG 4.36Å; A80-I404 HydrophobicContact CB-CD1 3.61Å; A80-I404 HydrophobicContact CB-CG1 4Å
81A98.4Very high95.8Very high0 Ų017.5 Ų17.50%09%0.086CC..EExtended strand (participates in β ladder)trans-75.8112.9168.400000107.8W26 F70 I83 I397 T401 Q402 V403 I404W26-A81 HydrophobicContact CH2-CB 4.03Å; F70-A81 HydrophobicContact CD2-CB 3.78Å; F70-A81 HydrophobicContact CE2-CB 4.17Å; F70-A81 HydrophobicContact CG-CB 4.3Å; A81-I83 HydrophobicContact CB-CD1 4.37Å; A81-I397 HydrophobicContact CB-CD1 4.25Å; A81-I397 HydrophobicContact CB-CG1 4.23Å; A81-I397 HydrophobicContact CB-CG2 4.29Å; A81-T401 HydrophobicContact CB-CG2 4.36Å; A81-Q402 PolarHBondContact N-O 3.49Å; A81-V403 HydrophobicContact CB-CG2 4.43Å; A81-V403 CarbonylContact O-C 3.54Å; A81-V403 WeakPolarHBondContact O-CA 3.14Å; A81-I404 PolarHBondContact O-N 3.34Å
82F98.6Very high95.8Very high0 Ų017.5 Ų17.50%09%0.086CC..EExtended strand (participates in β ladder)trans-92.4109.3177.2-173.8-85.5000108.4F56 Y59 Y60 F70 V71 F73 A80 V84 I404 P406F56-F82 HydrophobicContact CB-CE2 4.15Å; F56-F82 HydrophobicContact CB-CZ 4.23Å; F56-F82 HydrophobicContact CD1-CD2 4.47Å; F56-F82 AromaticContact CD1-CE2 3.63Å; F56-F82 HydrophobicContact CD1-CE2 3.63Å; F56-F82 HydrophobicContact CD1-CZ 4.49Å; F56-F82 HydrophobicContact CE1-CE2 4.41Å; F56-F82 HydrophobicContact CG-CE2 4.18Å; Y59-F82 AromaticContact CD1-CD1 3.91Å; Y59-F82 HydrophobicContact CD1-CD1 3.91Å; Y59-F82 HydrophobicContact CD1-CD2 4.38Å; Y59-F82 HydrophobicContact CD1-CE1 4.09Å; Y59-F82 HydrophobicContact CD1-CG 4.04Å; Y59-F82 HydrophobicContact CD1-CZ 4.41Å; Y59-F82 HydrophobicContact CE1-CG 4.47Å; Y60-F82 HydrophobicContact CD2-CE1 4.3Å; F70-F82 CarbonylContact C-O 3.58Å; F70-F82 VanDerWaalsContact CA-O 3.24Å; F70-F82 WeakPolarHBondContact CA-O 3.38Å; F70-F82 WeakPolarHBondContact CB-O 3.41Å; V71-F82 HydrophobicContact CG2-CB 4.13Å; V71-F82 HydrophobicContact CG2-CD1 4.02Å; V71-F82 HydrophobicContact CG2-CG 4.49Å; V71-F82 PolarHBondContact N-O 2.89Å; V71-F82 PolarHBondContact O-N 3.06Å; F73-F82 HydrophobicContact CB-CB 3.67Å; F73-F82 HydrophobicContact CB-CD2 4.42Å; F73-F82 HydrophobicContact CB-CG 4.4Å; F73-F82 HydrophobicContact CD2-CD2 4.17Å; F73-F82 HydrophobicContact CG-CB 4.39Å; F73-F82 HydrophobicContact CG-CD2 4.24Å; A80-F82 PolarHBondContact O-N 3.46Å; F82-V84 HydrophobicContact CD1-CG2 4.11Å; F82-I404 HydrophobicContact CD2-CB 4.11Å; F82-I404 HydrophobicContact CD2-CG2 3.73Å; F82-I404 HydrophobicContact CE2-CG2 3.94Å; F82-P406 HydrophobicContact CE1-CB 4.16Å; F82-P406 HydrophobicContact CE1-CG 3.71Å; F82-P406 HydrophobicContact CE2-CB 3.83Å; F82-P406 HydrophobicContact CE2-CG 4.17Å; F82-P406 HydrophobicContact CZ-CB 3.4Å; F82-P406 VanDerWaalsContact CZ-CB 3.4Å; F82-P406 HydrophobicContact CZ-CG 3.49Å; F82-P406 VanDerWaalsContact CZ-CG 3.49Å
83I98.6Very high95.8Very high0 Ų017.5 Ų17.50%09%0.086CC..EExtended strand (participates in β ladder)trans-76.8130.7-173.4-50.6-51.9000108.9F70 A81 D85 L88 A89 I92 I397 V403 I404 I405 P406 Y410F70-I83 HydrophobicContact CB-CD1 3.71Å; A81-I83 HydrophobicContact CB-CD1 4.37Å; I83-D85 VanDerWaalsContact CG2-O 3.29Å; I83-D85 WeakPolarHBondContact CG2-O 3.33Å; I83-L88 HydrophobicContact CD1-CD2 3.88Å; I83-L88 HydrophobicContact CD1-CG 4.31Å; I83-L88 HydrophobicContact CG2-CB 4.1Å; I83-L88 HydrophobicContact CG2-CD2 4.23Å; I83-L88 HydrophobicContact CG2-CG 4.06Å; I83-A89 HydrophobicContact CG2-CB 4.1Å; I83-I92 HydrophobicContact CD1-CD1 3.64Å; I83-I92 HydrophobicContact CG1-CD1 3.91Å; I83-I397 HydrophobicContact CD1-CD1 4.28Å; I83-V403 HydrophobicContact CD1-CG1 3.78Å; I83-V403 HydrophobicContact CG1-CG1 3.51Å; I83-I404 PolarHBondContact N-O 2.75Å; I83-I405 HydrophobicContact CB-CG1 4.1Å; I83-I405 HydrophobicContact CG1-CG1 3.86Å; I83-P406 WeakPolarHBondContact O-CD 3.44Å; I83-P406 WeakPolarHBondContact O-CG 3.23Å; I83-Y410 PolarHBondContact O-OH 3.34Å
84V97.6Very high95.9Very high7 Ų720.5 Ų20.54%0.04210%0.102CC..  trans-115.2-33.8-176.1-170.70000110.4Y60 R64 P69 V71 F82Y60-V84 HydrophobicContact CD2-CG1 4.06Å; Y60-V84 HydrophobicContact CE2-CB 4.46Å; Y60-V84 HydrophobicContact CE2-CG1 3.78Å; Y60-V84 WeakPolarHBondContact CE2-O 3.38Å; R64-V84 HydrophobicContact CB-CG1 3.92Å; P69-V84 PolarHBondContact O-N 2.92Å; V71-V84 HydrophobicContact CG1-CG2 4.3Å; V71-V84 HydrophobicContact CG2-CG2 3.77Å; F82-V84 HydrophobicContact CD1-CG2 4.11Å
85D97.2Very high96Very high58 Ų5826.6 Ų26.631%0.3113%0.128SC..  trans-86.5127.9175.8169.433.2000111.6P69 I83 Q87 L88 A89 Y410P69-D85 HydrophobicContact CB-CB 3.97Å; P69-D85 PolarHBondContact O-N 3.09Å; I83-D85 VanDerWaalsContact CG2-O 3.29Å; I83-D85 WeakPolarHBondContact CG2-O 3.33Å; D85-Q87 VanDerWaalsContact C-N 3.28Å; D85-Q87 PolarHBondContact O-N 3.49Å; D85-Q87 WeakPolarHBondContact OD1-CB 3.45Å; D85-Q87 PolarHBondContact OD1-N 3.31Å; D85-L88 HydrophobicContact CB-CB 4.25Å; D85-L88 PolarHBondContact O-N 3.23Å; D85-L88 PolarHBondContact OD2-N 3.39Å; D85-A89 PolarHBondContact O-N 2.98Å; D85-Y410 PolarHBondContact O-OH 2.86Å
86T97.3Very high96.4Very high28 Ų2827.6 Ų27.617%0.17214%0.135CC..Hα-helixtrans-66.3-30.3176.956.40000111.6A89 K90 Y410 L416 E440T86-A89 WeakPolarHBondContact O-CB 3.39Å; T86-A89 PolarHBondContact O-N 2.9Å; T86-K90 PolarHBondContact O-N 3.47Å; T86-Y410 HydrophobicContact CG2-CD2 4.03Å; T86-Y410 HydrophobicContact CG2-CE2 3.92Å; T86-Y410 HydrophobicContact CG2-CG 4.38Å; T86-L416 HydrophobicContact CG2-CD1 4.09Å; T86-E440 HydrophobicContact CG2-CG 4.34Å
87Q97.2Very high96.9Very high75 Ų7528.5 Ų28.535%0.3514%0.139SC..Hα-helixtrans-69.4-40.1177.4-175.55468.600111.7D85 A89 K90 N91D85-Q87 VanDerWaalsContact C-N 3.28Å; D85-Q87 PolarHBondContact O-N 3.49Å; D85-Q87 WeakPolarHBondContact OD1-CB 3.45Å; D85-Q87 PolarHBondContact OD1-N 3.31Å; Q87-A89 VanDerWaalsContact C-N 3.34Å; Q87-K90 WeakPolarHBondContact O-CB 3.48Å; Q87-K90 PolarHBondContact O-N 2.91Å; Q87-N91 PolarHBondContact NE2-OD1 2.86Å; Q87-N91 VanDerWaalsContact NE2-OD1 3.13Å; Q87-N91 VanDerWaalsContact O-CG 3.31Å; Q87-N91 PolarHBondContact O-N 3.37Å; Q87-N91 PolarHBondContact O-OD1 3.27Å
88L98.4Very high97.4Very high2 Ų231.4 Ų31.41%0.0116%0.164CC..Hα-helixtrans-63-39.4168.9-179.855.9000111.7P69 F70 I83 D85 K90 N91 I92 Y387 V389P69-L88 HydrophobicContact CB-CB 4.36Å; P69-L88 HydrophobicContact CB-CD2 3.84Å; P69-L88 HydrophobicContact CG-CD2 4.4Å; F70-L88 HydrophobicContact CB-CD2 4.12Å; F70-L88 HydrophobicContact CD1-CD2 4Å; I83-L88 HydrophobicContact CD1-CD2 3.88Å; I83-L88 HydrophobicContact CD1-CG 4.31Å; I83-L88 HydrophobicContact CG2-CB 4.1Å; I83-L88 HydrophobicContact CG2-CD2 4.23Å; I83-L88 HydrophobicContact CG2-CG 4.06Å; D85-L88 HydrophobicContact CB-CB 4.25Å; D85-L88 PolarHBondContact O-N 3.23Å; D85-L88 PolarHBondContact OD2-N 3.39Å; L88-K90 VanDerWaalsContact C-N 3.34Å; L88-K90 PolarHBondContact O-N 2.99Å; L88-N91 PolarHBondContact O-N 3.45Å; L88-I92 HydrophobicContact CD1-CD1 3.85Å; L88-I92 HydrophobicContact CD1-CG1 4.1Å; L88-I92 HydrophobicContact CD2-CD1 4.46Å; L88-I92 HydrophobicContact CG-CD1 3.8Å; L88-I92 HydrophobicContact CG-CG1 4.47Å; L88-I92 WeakPolarHBondContact O-CG1 3.32Å; L88-I92 PolarHBondContact O-N 3Å; L88-Y387 HydrophobicContact CD1-CE1 3.85Å; L88-V389 HydrophobicContact CD1-CG1 4.11Å; L88-V389 HydrophobicContact CD1-CG2 4.41Å; L88-V389 HydrophobicContact CD2-CG1 4.17Å; L88-V389 HydrophobicContact CD2-CG2 4.22Å
89A98.6Very high97.9Very high0 Ų030 Ų300%016%0.158CC..Hα-helixtrans-60.2-42.3173.800000112I83 D85 T86 Q87 N91 I92 L93 I405 Y410I83-A89 HydrophobicContact CG2-CB 4.1Å; D85-A89 PolarHBondContact O-N 2.98Å; T86-A89 WeakPolarHBondContact O-CB 3.39Å; T86-A89 PolarHBondContact O-N 2.9Å; Q87-A89 VanDerWaalsContact C-N 3.34Å; A89-N91 VanDerWaalsContact C-N 3.34Å; A89-N91 PolarHBondContact O-N 3.43Å; A89-I92 PolarHBondContact O-N 3.01Å; A89-L93 WeakPolarHBondContact O-CB 3.44Å; A89-L93 VanDerWaalsContact O-CG 3.26Å; A89-L93 WeakPolarHBondContact O-CG 3.38Å; A89-L93 PolarHBondContact O-N 3.34Å; A89-I405 HydrophobicContact CB-CD1 4.39Å; A89-I405 HydrophobicContact CB-CG1 4.39Å; A89-I405 HydrophobicContact CB-CG2 3.98Å; A89-Y410 HydrophobicContact CB-CE2 3.98Å
90K98.4Very high98.1Very high42 Ų4229.1 Ų29.118%0.18315%0.152CC..Hα-helixtrans-59-42.4173.5-169.8171.7177.8176.10112.4T86 Q87 L88 I94 K95 E437 V439T86-K90 PolarHBondContact O-N 3.47Å; Q87-K90 WeakPolarHBondContact O-CB 3.48Å; Q87-K90 PolarHBondContact O-N 2.91Å; L88-K90 VanDerWaalsContact C-N 3.34Å; L88-K90 PolarHBondContact O-N 2.99Å; K90-I94 HydrophobicContact CG-CD1 4.19Å; K90-I94 WeakPolarHBondContact O-CB 3.37Å; K90-I94 PolarHBondContact O-N 2.8Å; K90-K95 PolarHBondContact O-N 3.18Å; K90-E437 WeakPolarHBondContact CE-OE2 3.36Å; K90-E437 IonicContact NZ-OE1 2.99Å; K90-E437 PolarHBondContact NZ-OE1 3.31Å; K90-E437 IonicContact NZ-OE2 2.66Å; K90-E437 PolarHBondContact NZ-OE2 3.45Å; K90-V439 HydrophobicContact CB-CG1 4.03Å; K90-V439 HydrophobicContact CB-CG2 3.91Å; K90-V439 HydrophobicContact CG-CG1 4.33Å
91N98.5Very high98.1Very high16 Ų1629.8 Ų29.89%0.08616%0.158CC..Iπ-helixtrans-63.1-49.8176.7-65-8.7000110.6Q87 L88 A89 L93 K95 D96Q87-N91 PolarHBondContact NE2-OD1 2.86Å; Q87-N91 VanDerWaalsContact NE2-OD1 3.13Å; Q87-N91 VanDerWaalsContact O-CG 3.31Å; Q87-N91 PolarHBondContact O-N 3.37Å; Q87-N91 PolarHBondContact O-OD1 3.27Å; L88-N91 PolarHBondContact O-N 3.45Å; A89-N91 VanDerWaalsContact C-N 3.34Å; A89-N91 PolarHBondContact O-N 3.43Å; N91-L93 PolarHBondContact O-N 3.05Å; N91-K95 PolarHBondContact O-N 2.99Å; N91-K95 VanDerWaalsContact O-N 3.16Å; N91-K95 WeakPolarHBondContact OD1-CD 3.32Å; N91-D96 WeakPolarHBondContact O-CA 3.47Å; N91-D96 PolarHBondContact O-N 2.64Å
92I98.6Very high98Very high0 Ų030.8 Ų30.80%016%0.164CC..Iπ-helixtrans-64.4-42.7-177.8-70.1169.4000112.5I83 L88 A89 F100 R381 I397 V403 I405I83-I92 HydrophobicContact CD1-CD1 3.64Å; I83-I92 HydrophobicContact CG1-CD1 3.91Å; L88-I92 HydrophobicContact CD1-CD1 3.85Å; L88-I92 HydrophobicContact CD1-CG1 4.1Å; L88-I92 HydrophobicContact CD2-CD1 4.46Å; L88-I92 HydrophobicContact CG-CD1 3.8Å; L88-I92 HydrophobicContact CG-CG1 4.47Å; L88-I92 WeakPolarHBondContact O-CG1 3.32Å; L88-I92 PolarHBondContact O-N 3Å; A89-I92 PolarHBondContact O-N 3.01Å; I92-F100 HydrophobicContact CB-CD2 4.18Å; I92-F100 HydrophobicContact CB-CE2 4.43Å; I92-F100 HydrophobicContact CB-CG 4.4Å; I92-F100 HydrophobicContact CG1-CD2 4.04Å; I92-F100 HydrophobicContact CG1-CE1 4.35Å; I92-F100 HydrophobicContact CG1-CE2 3.79Å; I92-F100 HydrophobicContact CG1-CG 4.44Å; I92-F100 HydrophobicContact CG1-CZ 3.95Å; I92-F100 HydrophobicContact CG2-CB 3.97Å; I92-F100 HydrophobicContact CG2-CD1 4.08Å; I92-F100 HydrophobicContact CG2-CD2 4.06Å; I92-F100 HydrophobicContact CG2-CG 3.78Å; I92-R381 HydrophobicContact CG2-CB 4.23Å; I92-R381 HydrophobicContact CG2-CG 3.97Å; I92-I397 HydrophobicContact CD1-CD1 4.19Å; I92-V403 HydrophobicContact CD1-CG1 3.96Å; I92-V403 HydrophobicContact CG2-CG1 4.26Å; I92-I405 HydrophobicContact CG2-CD1 4.11Å
93L98.6Very high97.8Very high0 Ų032.3 Ų32.30%017%0.169CC..Iπ-helixtrans-78.1-33.4-175.8-67.4176.4000112.7A89 N91 L379 R381 I405 V439 L442 D446 G447A89-L93 WeakPolarHBondContact O-CB 3.44Å; A89-L93 VanDerWaalsContact O-CG 3.26Å; A89-L93 WeakPolarHBondContact O-CG 3.38Å; A89-L93 PolarHBondContact O-N 3.34Å; N91-L93 PolarHBondContact O-N 3.05Å; L93-L379 HydrophobicContact CD1-CD1 3.95Å; L93-L379 HydrophobicContact CD2-CD1 4.05Å; L93-R381 HydrophobicContact CD2-CG 4.48Å; L93-R381 VanDerWaalsContact CD2-NH2 3.3Å; L93-I405 HydrophobicContact CD1-CD1 3.95Å; L93-I405 HydrophobicContact CD2-CD1 3.53Å; L93-I405 HydrophobicContact CG-CD1 3.59Å; L93-V439 HydrophobicContact CD1-CG1 4.11Å; L93-L442 HydrophobicContact CD1-CD1 4.29Å; L93-L442 HydrophobicContact CD1-CD2 3.86Å; L93-D446 HydrophobicContact CD1-CB 4.2Å; L93-G447 WeakPolarHBondContact O-CA 3.31Å
94I98.3Very high97.5Very high63 Ų6332.8 Ų32.832%0.32317%0.174SC..Iπ-helixtrans-122.8-67.6-166.9-48.5178.5000111.6K90 F97 V439 D446K90-I94 HydrophobicContact CG-CD1 4.19Å; K90-I94 WeakPolarHBondContact O-CB 3.37Å; K90-I94 PolarHBondContact O-N 2.8Å; I94-F97 WeakPolarHBondContact O-CB 3.45Å; I94-V439 HydrophobicContact CD1-CG1 4.23Å; I94-D446 WeakPolarHBondContact CD1-OD2 3.21Å
95K97.9Very high97.1Very high128 Ų12834.1 Ų34.156%0.55718%0.18SC*.Iπ-helixtrans-67.7-47.5-167-58.5-172.5-1741660112.7K90 N91K90-K95 PolarHBondContact O-N 3.18Å; N91-K95 PolarHBondContact O-N 2.99Å; N91-K95 VanDerWaalsContact O-N 3.16Å; N91-K95 WeakPolarHBondContact OD1-CD 3.32Å
96D97.9Very high96.7Very high53 Ų5331.7 Ų31.728%0.28317%0.167SC..THydrogen-bonded Turntrans-105.423.3-175.9-57-41.3000111.6N91 S98 N99 F100 Y387N91-D96 WeakPolarHBondContact O-CA 3.47Å; N91-D96 PolarHBondContact O-N 2.64Å; D96-S98 PolarHBondContact O-N 3.06Å; D96-N99 PolarHBondContact O-N 3.49Å; D96-F100 HydrophobicContact CB-CD2 4.39Å; D96-F100 HydrophobicContact CB-CE2 4.34Å; D96-F100 WeakPolarHBondContact O-CD2 3.46Å; D96-Y387 HydrophobicContact CB-CE2 3.9Å; D96-Y387 VanDerWaalsContact OD2-CE2 3.29Å; D96-Y387 WeakPolarHBondContact OD2-CE2 3.44Å; D96-Y387 PolarHBondContact OD2-OH 2.96Å
97F97.9Very high96.4Very high23 Ų2332.9 Ų32.910%0.10117%0.17CC..G310 helixtrans-52.3-31.7-176.3174.8-98.3000113.1I94 N99 F100 A101 W126 P448 R449I94-F97 WeakPolarHBondContact O-CB 3.45Å; F97-N99 PolarHBondContact O-N 2.66Å; F97-F100 CarbonylContact O-C 3.35Å; F97-F100 WeakPolarHBondContact O-CA 3.32Å; F97-F100 PolarHBondContact O-N 3.24Å; F97-A101 HydrophobicContact CE1-CB 3.96Å; F97-A101 HydrophobicContact CZ-CB 3.93Å; F97-A101 WeakPolarHBondContact O-CA 3.31Å; F97-A101 PolarHBondContact O-N 3.31Å; F97-W126 AromaticContact CE1-CH2 3.84Å; F97-W126 HydrophobicContact CE1-CH2 3.84Å; F97-W126 AromaticContact CE1-CZ3 3.97Å; F97-W126 HydrophobicContact CE1-CZ3 3.97Å; F97-W126 AromaticContact CZ-CH2 3.45Å; F97-W126 HydrophobicContact CZ-CH2 3.45Å; F97-W126 VanDerWaalsContact CZ-CH2 3.45Å; F97-W126 HydrophobicContact CZ-CZ2 4.28Å; F97-W126 AromaticContact CZ-CZ3 3.8Å; F97-W126 HydrophobicContact CZ-CZ3 3.8Å; F97-P448 HydrophobicContact CB-CG 4.44Å; F97-P448 HydrophobicContact CD1-CB 3.91Å; F97-P448 HydrophobicContact CD1-CG 3.64Å; F97-P448 HydrophobicContact CD2-CG 4.35Å; F97-P448 HydrophobicContact CE1-CB 3.68Å; F97-P448 HydrophobicContact CE1-CG 3.98Å; F97-P448 HydrophobicContact CE2-CB 4.37Å; F97-P448 HydrophobicContact CG-CB 4.35Å; F97-P448 HydrophobicContact CG-CG 3.85Å; F97-P448 HydrophobicContact CZ-CB 3.94Å; F97-P448 HydrophobicContact CZ-CG 4.47Å; F97-R449 HydrophobicContact CE2-CB 3.62Å; F97-R449 HydrophobicContact CZ-CB 3.84Å
98S97.4Very high96Very high100 Ų10029.7 Ų29.770%0.69916%0.156SC*.G310 helixtrans-56.9-32.6177.359.70000113D96D96-S98 PolarHBondContact O-N 3.06Å
99N98.3Very high95.5Very high16 Ų1630.4 Ų30.49%0.08616%0.163CC..G310 helixtrans-85.1-13.3175.8-165.343.5000113.4D96 F97 A383 L384 N385D96-N99 PolarHBondContact O-N 3.49Å; F97-N99 PolarHBondContact O-N 2.66Å; N99-A383 CarbonylContact O-C 3.38Å; N99-L384 WeakPolarHBondContact O-CB 3.49Å; N99-L384 WeakPolarHBondContact O-CG 3.44Å; N99-L384 PolarHBondContact O-N 2.9Å; N99-N385 PolarHBondContact ND2-O 2.86Å; N99-N385 WeakPolarHBondContact OD1-CA 3.45Å; N99-N385 VanDerWaalsContact OD1-CB 3.28Å; N99-N385 WeakPolarHBondContact OD1-CB 3.49Å; N99-N385 PolarHBondContact OD1-N 2.97Å; N99-N385 PolarHBondContact OD1-ND2 3.36Å; N99-N385 VanDerWaalsContact OD1-ND2 3.12Å; N99-N385 PolarHBondContact OD1-O 3.19Å
100F98.4Very high94.9Very high0 Ų038.8 Ų38.80%020%0.195CC..G310 helixtrans-12530.1-175.7-61.5-76.2000111I92 D96 F97 D102 R381 A383 Y387 I397 V403I92-F100 HydrophobicContact CB-CD2 4.18Å; I92-F100 HydrophobicContact CB-CE2 4.43Å; I92-F100 HydrophobicContact CB-CG 4.4Å; I92-F100 HydrophobicContact CG1-CD2 4.04Å; I92-F100 HydrophobicContact CG1-CE1 4.35Å; I92-F100 HydrophobicContact CG1-CE2 3.79Å; I92-F100 HydrophobicContact CG1-CG 4.44Å; I92-F100 HydrophobicContact CG1-CZ 3.95Å; I92-F100 HydrophobicContact CG2-CB 3.97Å; I92-F100 HydrophobicContact CG2-CD1 4.08Å; I92-F100 HydrophobicContact CG2-CD2 4.06Å; I92-F100 HydrophobicContact CG2-CG 3.78Å; D96-F100 HydrophobicContact CB-CD2 4.39Å; D96-F100 HydrophobicContact CB-CE2 4.34Å; D96-F100 WeakPolarHBondContact O-CD2 3.46Å; F97-F100 CarbonylContact O-C 3.35Å; F97-F100 WeakPolarHBondContact O-CA 3.32Å; F97-F100 PolarHBondContact O-N 3.24Å; F100-D102 PolarHBondContact O-N 3.49Å; F100-R381 HydrophobicContact CB-CB 4.09Å; F100-R381 HydrophobicContact CB-CG 4.34Å; F100-R381 HydrophobicContact CD1-CB 4.48Å; F100-R381 WeakPolarHBondContact O-CD 3.34Å; F100-A383 HydrophobicContact CD1-CB 4.31Å; F100-A383 HydrophobicContact CE1-CB 3.82Å; F100-Y387 HydrophobicContact CE2-CD1 4.21Å; F100-Y387 AromaticContact CE2-CD2 3.77Å; F100-Y387 HydrophobicContact CE2-CD2 3.77Å; F100-Y387 HydrophobicContact CE2-CE1 4.38Å; F100-Y387 AromaticContact CE2-CE2 3.95Å; F100-Y387 HydrophobicContact CE2-CE2 3.95Å; F100-Y387 AromaticContact CE2-CG 3.89Å; F100-Y387 HydrophobicContact CE2-CG 3.89Å; F100-Y387 AromaticContact CZ-CD1 3.79Å; F100-Y387 HydrophobicContact CZ-CD1 3.79Å; F100-Y387 AromaticContact CZ-CD2 3.94Å; F100-Y387 HydrophobicContact CZ-CD2 3.94Å; F100-Y387 HydrophobicContact CZ-CE1 4.32Å; F100-Y387 HydrophobicContact CZ-CE2 4.45Å; F100-Y387 AromaticContact CZ-CG 3.56Å; F100-Y387 HydrophobicContact CZ-CG 3.56Å; F100-I397 HydrophobicContact CE1-CG2 4.49Å; F100-V403 HydrophobicContact CD1-CG2 4.18Å; F100-V403 HydrophobicContact CE1-CG2 3.98Å
101A97.1Very high94.5Very high15 Ų1538 Ų3812%0.12419%0.193CC..  trans-67.7-28.3-173.100000112.4F97 L384 R449F97-A101 HydrophobicContact CE1-CB 3.96Å; F97-A101 HydrophobicContact CZ-CB 3.93Å; F97-A101 WeakPolarHBondContact O-CA 3.31Å; F97-A101 PolarHBondContact O-N 3.31Å; A101-L384 HydrophobicContact CB-CD1 4.31Å; A101-R449 WeakPolarHBondContact O-CD 2.9Å; A101-R449 PolarHBondContact O-NH1 3.13Å
102D97.3Very high94.2Very high21 Ų2137.3 Ų37.311%0.11219%0.189CC..BIsolated β-bridgetrans-91.9152.6-171.1-74.7-2.9000113.7F100 D122 G123 R381 K382 L384 R449F100-D102 PolarHBondContact O-N 3.49Å; D102-D122 VanDerWaalsContact CA-OD1 3.3Å; D102-D122 WeakPolarHBondContact CA-OD1 3.49Å; D102-D122 HydrophobicContact CB-CB 4.17Å; D102-D122 WeakPolarHBondContact CB-OD1 3.34Å; D102-D122 VanDerWaalsContact CG-CB 3.49Å; D102-D122 VanDerWaalsContact CG-CG 3.5Å; D102-D122 WeakPolarHBondContact OD1-CB 3.35Å; D102-G123 PolarHBondContact OD1-N 3.03Å; D102-R381 CarbonylContact O-C 3.52Å; D102-R381 VanDerWaalsContact O-C 3.32Å; D102-R381 VanDerWaalsContact O-CA 3.25Å; D102-R381 WeakPolarHBondContact O-CA 3.32Å; D102-K382 HydrophobicContact CB-CB 4.29Å; D102-K382 PolarHBondContact O-N 3.39Å; D102-L384 HydrophobicContact CB-CD2 4.02Å; D102-L384 WeakPolarHBondContact OD2-CD2 3.42Å; D102-R449 IonicContact OD1-NH1 3.92Å
103R95Very high93.9Very high31 Ų3138.4 Ų38.412%0.11720%0.196CC..  trans-97-27.7168.4-67.9-174.5-178.3149.7-7112.5Q105 F119 D122 Q402 R449R103-Q105 HydrophobicContact CB-CG 4.06Å; R103-F119 VanDerWaalsContact NH1-CE2 3.25Å; R103-F119 PolarHBondContact NH1-O 3.25Å; R103-D122 PolarHBondContact N-OD1 2.62Å; R103-Q402 PolarHBondContact O-NE2 3.37Å; R103-Q402 PolarHBondContact O-OE1 3.33Å; R103-R449 PolarHBondContact NH2-O 2.71Å
104G90.9Very high93.7Very high10 Ų1038.4 Ų38.410%0.10320%0.196CC..  trans73.626.9-179.500000114.4D122G104-D122 WeakPolarHBondContact CA-OD2 3.13Å; G104-D122 PolarHBondContact N-OD2 3.23Å
105Q89.1Confident93.5Very high36 Ų3635.5 Ų35.517%0.16818%0.181CC..  trans-78.9160.6-177.7-75.8-60.9-38.800112.8R103 N120 E380R103-Q105 HydrophobicContact CB-CG 4.06Å; Q105-N120 HydrophobicContact CB-CB 4.45Å; Q105-E380 PolarHBondContact NE2-OE2 3.19Å
106F89.9Confident93.2Very high6 Ų630.8 Ų30.83%0.02616%0.161CC..  trans-69.8132.1175.2175.4-93.4000110.8N108 T115 N120 M227 P231 A234 M241F106-N108 HydrophobicContact CE1-CB 4.31Å; F106-N108 HydrophobicContact CZ-CB 3.88Å; F106-T115 HydrophobicContact CE1-CG2 4.46Å; F106-N120 PolarHBondContact O-ND2 2.92Å; F106-M227 HydrophobicContact CZ-SD 4.46Å; F106-P231 HydrophobicContact CB-CB 3.92Å; F106-P231 HydrophobicContact CD2-CB 4.1Å; F106-A234 HydrophobicContact CD2-CB 4.06Å; F106-A234 HydrophobicContact CE2-CB 3.66Å; F106-M241 HydrophobicContact CB-CE 4.4Å; F106-M241 HydrophobicContact CD1-CB 4.12Å; F106-M241 HydrophobicContact CD1-CE 3.82Å; F106-M241 HydrophobicContact CE1-CB 3.89Å; F106-M241 HydrophobicContact CE1-CE 4.43Å; F106-M241 HydrophobicContact CG-CE 4.24Å
107H89.8Confident93Very high54 Ų5428.9 Ų28.925%0.2515%0.151CC..  trans-150.3146.3162.864.980.2000110.5T115 Q116 N120H107-T115 WeakPolarHBondContact CB-O 3.46Å; H107-Q116 HydrophobicContact CB-CG 4.49Å; H107-N120 HydrophobicContact CB-CB 4.16Å; H107-N120 PolarHBondContact CD2-O 3.19Å
108N90.3Very high92.9Very high7 Ų728.4 Ų28.44%0.03715%0.149CC..BIsolated β-bridgetrans-137.885.4176.4-178.14.6000110.1F106 R110 D111 D112 T115 M239F106-N108 HydrophobicContact CE1-CB 4.31Å; F106-N108 HydrophobicContact CZ-CB 3.88Å; N108-R110 PolarHBondContact O-N 2.66Å; N108-R110 PolarHBondContact OD1-N 3.03Å; N108-D111 WeakPolarHBondContact ND2-CB 3.39Å; N108-D111 PolarHBondContact ND2-OD2 3.46Å; N108-D111 PolarHBondContact OD1-N 3.34Å; N108-D112 HydrophobicContact CB-CB 4.37Å; N108-D112 CarbonylContact O-C 3.53Å; N108-D112 WeakPolarHBondContact O-CA 3.31Å; N108-D112 WeakPolarHBondContact O-CB 3.28Å; N108-D112 PolarHBondContact O-N 2.79Å; N108-T115 PolarHBondContact N-OG1 3.44Å; N108-M239 PolarHBondContact ND2-O 2.97Å; N108-M239 VanDerWaalsContact ND2-O 3.08Å
109G87.2Confident92.8Very high17 Ų1727.9 Ų27.918%0.17513%0.134CC..THydrogen-bonded Turntrans-67.4-21.1-177.700000115.5Q116G109-Q116 VanDerWaalsContact CA-CG 3.48Å
110R87Confident92.6Very high176 Ų17628 Ų2866%0.66414%0.135SC*.THydrogen-bonded Turntrans-71.8-50.5-178.8-179.5-169.8174.2170.83.9110.8N108N108-R110 PolarHBondContact O-N 2.66Å; N108-R110 PolarHBondContact OD1-N 3.03Å
111D89.8Confident92.4Very high26 Ų2628.2 Ų28.214%0.13914%0.136CC..THydrogen-bonded Turntrans-106.6-16.9-174.1-46.8-76000112.9N108 R238 R240N108-D111 WeakPolarHBondContact ND2-CB 3.39Å; N108-D111 PolarHBondContact ND2-OD2 3.46Å; N108-D111 PolarHBondContact OD1-N 3.34Å; D111-R238 WeakPolarHBondContact OD2-CB 3.48Å; D111-R238 WeakPolarHBondContact OD2-CG 3.37Å; D111-R240 HydrophobicContact CB-CG 4.36Å; D111-R240 WeakPolarHBondContact O-CD 3.43Å; D111-R240 PolarHBondContact O-NE 2.78Å; D111-R240 PolarHBondContact O-NH2 3.12Å
112D91.4Very high92.3Very high1 Ų129 Ų291%0.00514%0.138CC..BIsolated β-bridgetrans-137.867.3178.2-165.5-0.8000112.1N108 L114 T115 R240 M241 M242N108-D112 HydrophobicContact CB-CB 4.37Å; N108-D112 CarbonylContact O-C 3.53Å; N108-D112 WeakPolarHBondContact O-CA 3.31Å; N108-D112 WeakPolarHBondContact O-CB 3.28Å; N108-D112 PolarHBondContact O-N 2.79Å; D112-L114 PolarHBondContact O-N 3.36Å; D112-T115 HydrophobicContact CB-CG2 4.11Å; D112-T115 VanDerWaalsContact CG-CG2 3.48Å; D112-T115 WeakPolarHBondContact O-CB 3.4Å; D112-T115 PolarHBondContact O-N 3.44Å; D112-T115 PolarHBondContact O-OG1 3Å; D112-T115 WeakPolarHBondContact OD2-CG2 3.19Å; D112-R240 HydrophobicContact CB-CB 4.15Å; D112-R240 HydrophobicContact CB-CG 4.13Å; D112-M241 WeakPolarHBondContact OD2-CA 3.5Å; D112-M241 PolarHBondContact OD2-N 2.77Å; D112-M242 WeakPolarHBondContact OD1-CB 3.49Å; D112-M242 WeakPolarHBondContact OD1-CG 3.23Å; D112-M242 PolarHBondContact OD2-N 2.63Å
113P93Very high92.2Very high23 Ų2329.6 Ų29.615%0.14915%0.15CC..G310 helixtrans-45.4-40.6-174.5-31.431.4000115.6T115 Q116 M251 A302P113-T115 PolarHBondContact O-N 2.96Å; P113-Q116 WeakPolarHBondContact O-CB 3.39Å; P113-Q116 PolarHBondContact O-N 2.77Å; P113-M251 HydrophobicContact CB-SD 4.41Å; P113-A302 WeakPolarHBondContact O-CB 3.35Å
114L94.2Very high92Very high0 Ų034.4 Ų34.40%017%0.172CC..G310 helixtrans-60.4-22.7-176.9-62.3-172.3000113.2D112 Q116 H117 M242 H247 F250 M251 A301 F305D112-L114 PolarHBondContact O-N 3.36Å; L114-Q116 VanDerWaalsContact C-N 3.26Å; L114-Q116 PolarHBondContact O-N 2.99Å; L114-H117 PolarHBondContact O-CD2 3.42Å; L114-M242 HydrophobicContact CB-CG 4.09Å; L114-H247 HydrophobicContact CD1-CB 4.45Å; L114-F250 HydrophobicContact CD1-CB 3.95Å; L114-F250 HydrophobicContact CD1-CD2 4.41Å; L114-F250 HydrophobicContact CD2-CB 4.15Å; L114-M251 HydrophobicContact CD2-SD 4.12Å; L114-A301 HydrophobicContact CD2-CB 3.87Å; L114-F305 HydrophobicContact CB-CD1 4.17Å; L114-F305 HydrophobicContact CB-CG 4.34Å; L114-F305 HydrophobicContact CD1-CD2 4.13Å; L114-F305 HydrophobicContact CD1-CG 4.23Å; L114-F305 HydrophobicContact CD2-CB 4.06Å
115T93.3Very high92.1Very high2 Ų239.3 Ų39.31%0.01219%0.19CC..G310 helixtrans-72.8-15.1176.463.20000113.7F106 H107 N108 D112 P113 H117 N120 M241 M242F106-T115 HydrophobicContact CE1-CG2 4.46Å; H107-T115 WeakPolarHBondContact CB-O 3.46Å; N108-T115 PolarHBondContact N-OG1 3.44Å; D112-T115 HydrophobicContact CB-CG2 4.11Å; D112-T115 VanDerWaalsContact CG-CG2 3.48Å; D112-T115 WeakPolarHBondContact O-CB 3.4Å; D112-T115 PolarHBondContact O-N 3.44Å; D112-T115 PolarHBondContact O-OG1 3Å; D112-T115 WeakPolarHBondContact OD2-CG2 3.19Å; P113-T115 PolarHBondContact O-N 2.96Å; T115-H117 PolarHBondContact O-N 3.04Å; T115-H117 VanDerWaalsContact O-N 3.09Å; T115-N120 WeakPolarHBondContact O-CB 3.49Å; T115-N120 PolarHBondContact O-ND2 3.44Å; T115-N120 VanDerWaalsContact O-ND2 3.15Å; T115-M241 HydrophobicContact CG2-CB 4.03Å; T115-M242 HydrophobicContact CG2-CG 4.28Å
116Q92.5Very high92.3Very high29 Ų2938.4 Ų38.414%0.13619%0.185CC..  trans-84.142.9177.1-79.8-166.1-18.600113.4H107 G109 P113 L114 L121 Q303H107-Q116 HydrophobicContact CB-CG 4.49Å; G109-Q116 VanDerWaalsContact CA-CG 3.48Å; P113-Q116 WeakPolarHBondContact O-CB 3.39Å; P113-Q116 PolarHBondContact O-N 2.77Å; L114-Q116 VanDerWaalsContact C-N 3.26Å; L114-Q116 PolarHBondContact O-N 2.99Å; Q116-L121 HydrophobicContact CB-CD2 4.11Å; Q116-L121 HydrophobicContact CG-CD2 4.2Å; Q116-Q303 PolarHBondContact O-NE2 3.44Å; Q116-Q303 VanDerWaalsContact O-NE2 3.12Å
117H94.2Very high92.5Very high14 Ų1442.4 Ų42.47%0.06520%0.202CC..SBendtrans-93.3159.1177.262.351.9000112.3L114 T115 F119 N120 L121 A302 F305 I306L114-H117 PolarHBondContact O-CD2 3.42Å; T115-H117 PolarHBondContact O-N 3.04Å; T115-H117 VanDerWaalsContact O-N 3.09Å; H117-F119 PolarHBondContact ND1-N 3.39Å; H117-F119 PolarHBondContact O-N 2.98Å; H117-N120 PolarHBondContact CE1-ND2 3.07Å; H117-N120 PolarHBondContact ND1-N 3.37Å; H117-N120 PolarHBondContact NE2-ND2 2.97Å; H117-N120 PolarHBondContact O-N 2.89Å; H117-L121 PolarHBondContact O-N 3.34Å; H117-L121 VanDerWaalsContact O-N 3.16Å; H117-A302 HydrophobicContact CB-CB 4.07Å; H117-A302 VanDerWaalsContact CB-O 3.24Å; H117-A302 WeakPolarHBondContact CB-O 3.36Å; H117-F305 AromaticContact CD2-CD1 3.94Å; H117-I306 HydrophobicContact CB-CB 3.65Å; H117-I306 HydrophobicContact CB-CG1 4.29Å; H117-I306 HydrophobicContact CB-CG2 3.64Å
118L95.3Very high92.5Very high13 Ų1340.7 Ų40.77%0.06820%0.195CC..THydrogen-bonded Turntrans-44.8-36.5-176.1-17968000114.4M129 R130 L133 I452L118-M129 HydrophobicContact CB-CG 4.29Å; L118-M129 HydrophobicContact CD1-CB 4.03Å; L118-M129 HydrophobicContact CD1-CG 3.88Å; L118-R130 HydrophobicContact CD1-CB 3.91Å; L118-L133 HydrophobicContact CB-CD1 4.17Å; L118-L133 HydrophobicContact CD1-CD1 4.41Å; L118-L133 HydrophobicContact CD2-CD1 3.94Å; L118-L133 HydrophobicContact CG-CD1 4.39Å; L118-I452 HydrophobicContact CD2-CB 4.34Å; L118-I452 HydrophobicContact CD2-CD1 3.87Å; L118-I452 HydrophobicContact CD2-CG2 4.04Å
119F94.6Very high92.6Very high88 Ų8840.5 Ų40.539%0.38619%0.194SC..THydrogen-bonded Turntrans-65.6-36.8179.8-178.3-77.9000113.7R103 H117 I306R103-F119 VanDerWaalsContact NH1-CE2 3.25Å; R103-F119 PolarHBondContact NH1-O 3.25Å; H117-F119 PolarHBondContact ND1-N 3.39Å; H117-F119 PolarHBondContact O-N 2.98Å; F119-I306 HydrophobicContact CB-CD1 4.31Å; F119-I306 HydrophobicContact CB-CG1 4.28Å
120N94.2Very high92.9Very high19 Ų1941.4 Ų41.410%0.10219%0.192CC..THydrogen-bonded Turntrans-97.1-25-174.5-74.9-15.9000114Q105 F106 H107 T115 H117Q105-N120 HydrophobicContact CB-CB 4.45Å; F106-N120 PolarHBondContact O-ND2 2.92Å; H107-N120 HydrophobicContact CB-CB 4.16Å; H107-N120 PolarHBondContact CD2-O 3.19Å; T115-N120 WeakPolarHBondContact O-CB 3.49Å; T115-N120 PolarHBondContact O-ND2 3.44Å; T115-N120 VanDerWaalsContact O-ND2 3.15Å; H117-N120 PolarHBondContact CE1-ND2 3.07Å; H117-N120 PolarHBondContact ND1-N 3.37Å; H117-N120 PolarHBondContact NE2-ND2 2.97Å; H117-N120 PolarHBondContact O-N 2.89Å
121L94.8Very high93Very high5 Ų535.6 Ų35.63%0.02617%0.172CC..  trans-58.2149.9-179.4-70.6174.9000111Q116 H117 K125 W126 M129 R449Q116-L121 HydrophobicContact CB-CD2 4.11Å; Q116-L121 HydrophobicContact CG-CD2 4.2Å; H117-L121 PolarHBondContact O-N 3.34Å; H117-L121 VanDerWaalsContact O-N 3.16Å; L121-K125 HydrophobicContact CD2-CB 4.28Å; L121-K125 HydrophobicContact CD2-CD 4.49Å; L121-W126 HydrophobicContact CB-CB 3.99Å; L121-W126 WeakPolarHBondContact O-CB 3.19Å; L121-M129 HydrophobicContact CD1-CB 3.94Å; L121-M129 HydrophobicContact CD1-CE 4.44Å; L121-M129 HydrophobicContact CD1-CG 4.03Å; L121-R449 PolarHBondContact O-NH1 3.46Å; L121-R449 PolarHBondContact O-NH2 3.21Å
122D94.7Very high92.7Very high30 Ų3035.7 Ų35.716%0.1617%0.171CC..  trans-130.6168.1177.7-83.5-23.2000111.1D102 R103 G104 K125 W126 R449D102-D122 VanDerWaalsContact CA-OD1 3.3Å; D102-D122 WeakPolarHBondContact CA-OD1 3.49Å; D102-D122 HydrophobicContact CB-CB 4.17Å; D102-D122 WeakPolarHBondContact CB-OD1 3.34Å; D102-D122 VanDerWaalsContact CG-CB 3.49Å; D102-D122 VanDerWaalsContact CG-CG 3.5Å; D102-D122 WeakPolarHBondContact OD1-CB 3.35Å; R103-D122 PolarHBondContact N-OD1 2.62Å; G104-D122 WeakPolarHBondContact CA-OD2 3.13Å; G104-D122 PolarHBondContact N-OD2 3.23Å; D122-K125 PolarHBondContact O-N 3.43Å; D122-W126 PolarHBondContact O-N 3.13Å; D122-R449 IonicContact OD1-CZ 2.66Å; D122-R449 IonicContact OD1-NH1 2.65Å; D122-R449 PolarHBondContact OD1-NH1 3.32Å; D122-R449 VanDerWaalsContact OD1-NH1 3.13Å; D122-R449 IonicContact OD1-NH2 3.91Å; D122-R449 PolarHBondContact OD1-NH2 3.36Å
123G94.3Very high92.6Very high34 Ų3435.7 Ų35.735%0.35117%0.171SC..Hα-helixtrans56.5-140.8176.900000114D102 K125 W126 K127D102-G123 PolarHBondContact OD1-N 3.03Å; G123-K125 VanDerWaalsContact C-N 3.29Å; G123-K125 PolarHBondContact O-N 3Å; G123-W126 PolarHBondContact O-N 3.37Å; G123-K127 PolarHBondContact O-N 2.68Å; G123-K127 VanDerWaalsContact O-N 3.13Å
124K92.3Very high92.5Very high133 Ų13337.6 Ų37.658%0.57818%0.182SC*.Hα-helixtrans-57.9-39.8-178.5-170.4-178.5-172.2-56.70112.5W126 K127 D128K124-W126 VanDerWaalsContact C-N 3.32Å; K124-W126 PolarHBondContact O-N 2.87Å; K124-K127 PolarHBondContact O-N 2.98Å; K124-K127 VanDerWaalsContact O-N 3.17Å; K124-D128 IonicContact NZ-OD1 3.85Å; K124-D128 PolarHBondContact NZ-OD1 3.45Å; K124-D128 IonicContact NZ-OD2 3.63Å; K124-D128 PolarHBondContact NZ-OD2 3.3Å; K124-D128 WeakPolarHBondContact O-CB 3.5Å; K124-D128 PolarHBondContact O-N 3.34Å
125K91.6Very high92.1Very high112 Ų11241 Ų4149%0.48720%0.204SC..Hα-helixtrans-60.5-42.2179.9-69.5-167.6172.1-158.80112L121 D122 G123 M129L121-K125 HydrophobicContact CD2-CB 4.28Å; L121-K125 HydrophobicContact CD2-CD 4.49Å; D122-K125 PolarHBondContact O-N 3.43Å; G123-K125 VanDerWaalsContact C-N 3.29Å; G123-K125 PolarHBondContact O-N 3Å; K125-M129 WeakPolarHBondContact O-CB 3.22Å; K125-M129 PolarHBondContact O-N 3.19Å
126W95Very high91.6Very high18 Ų1841.5 Ų41.57%0.06821%0.207CC..Hα-helixtrans-64-47.3174.1169.377.7000112F97 L121 D122 G123 K124 D128 M129 R130 R449F97-W126 AromaticContact CE1-CH2 3.84Å; F97-W126 HydrophobicContact CE1-CH2 3.84Å; F97-W126 AromaticContact CE1-CZ3 3.97Å; F97-W126 HydrophobicContact CE1-CZ3 3.97Å; F97-W126 AromaticContact CZ-CH2 3.45Å; F97-W126 HydrophobicContact CZ-CH2 3.45Å; F97-W126 VanDerWaalsContact CZ-CH2 3.45Å; F97-W126 HydrophobicContact CZ-CZ2 4.28Å; F97-W126 AromaticContact CZ-CZ3 3.8Å; F97-W126 HydrophobicContact CZ-CZ3 3.8Å; L121-W126 HydrophobicContact CB-CB 3.99Å; L121-W126 WeakPolarHBondContact O-CB 3.19Å; D122-W126 PolarHBondContact O-N 3.13Å; G123-W126 PolarHBondContact O-N 3.37Å; K124-W126 VanDerWaalsContact C-N 3.32Å; K124-W126 PolarHBondContact O-N 2.87Å; W126-D128 PolarHBondContact O-N 3.38Å; W126-M129 PolarHBondContact O-N 3.47Å; W126-R130 HydrophobicContact CZ2-CB 4.32Å; W126-R130 HydrophobicContact CZ2-CG 4.2Å; W126-R130 VanDerWaalsContact O-CB 3.3Å; W126-R130 WeakPolarHBondContact O-CB 3.45Å; W126-R130 PolarHBondContact O-N 3.04Å; W126-R449 VanDerWaalsContact CD1-CZ 3.47Å; W126-R449 VanDerWaalsContact CE2-CD 3.44Å; W126-R449 HydrophobicContact CH2-CB 4.13Å; W126-R449 HydrophobicContact CH2-CG 4.34Å; W126-R449 HydrophobicContact CZ2-CB 3.59Å; W126-R449 HydrophobicContact CZ2-CG 3.46Å; W126-R449 VanDerWaalsContact CZ2-CG 3.46Å
127K93.4Very high91.4Very high90 Ų9041.1 Ų41.139%0.39121%0.205SC..Hα-helixtrans-58.1-51.1-179.7-173.9-170.8175-160.10110.8G123 K124 M129 R130 Q131 E290G123-K127 PolarHBondContact O-N 2.68Å; G123-K127 VanDerWaalsContact O-N 3.13Å; K124-K127 PolarHBondContact O-N 2.98Å; K124-K127 VanDerWaalsContact O-N 3.17Å; K127-M129 PolarHBondContact O-N 2.85Å; K127-R130 PolarHBondContact O-N 3.17Å; K127-Q131 WeakPolarHBondContact O-CG 3.07Å; K127-Q131 PolarHBondContact O-N 3.43Å; K127-E290 IonicContact NZ-OE1 3.94Å; K127-E290 IonicContact NZ-OE2 2.75Å
128D90.1Very high91.1Very high17 Ų1743.2 Ų43.29%0.09122%0.219CC..Hα-helixtrans-59.4-48.1178.8-64.8-5.9000110.5K124 W126 R130 Q131 R132 I292K124-D128 IonicContact NZ-OD1 3.85Å; K124-D128 PolarHBondContact NZ-OD1 3.45Å; K124-D128 IonicContact NZ-OD2 3.63Å; K124-D128 PolarHBondContact NZ-OD2 3.3Å; K124-D128 WeakPolarHBondContact O-CB 3.5Å; K124-D128 PolarHBondContact O-N 3.34Å; W126-D128 PolarHBondContact O-N 3.38Å; D128-R130 PolarHBondContact O-N 2.76Å; D128-Q131 PolarHBondContact O-N 3.06Å; D128-R132 VanDerWaalsContact O-CG 3.3Å; D128-R132 WeakPolarHBondContact O-CG 3.41Å; D128-R132 PolarHBondContact O-N 2.96Å; D128-I292 HydrophobicContact CB-CD1 4.29Å; D128-I292 HydrophobicContact CB-CG2 4.19Å
129M90.9Very high90.8Very high3 Ų345.6 Ų45.62%0.01524%0.237CC..Hα-helixtrans-64.3-40.6179.8-171.559.372.300111.9L118 L121 K125 W126 K127 Q131 R132 L133 M295 Q303L118-M129 HydrophobicContact CB-CG 4.29Å; L118-M129 HydrophobicContact CD1-CB 4.03Å; L118-M129 HydrophobicContact CD1-CG 3.88Å; L121-M129 HydrophobicContact CD1-CB 3.94Å; L121-M129 HydrophobicContact CD1-CE 4.44Å; L121-M129 HydrophobicContact CD1-CG 4.03Å; K125-M129 WeakPolarHBondContact O-CB 3.22Å; K125-M129 PolarHBondContact O-N 3.19Å; W126-M129 PolarHBondContact O-N 3.47Å; K127-M129 PolarHBondContact O-N 2.85Å; M129-Q131 VanDerWaalsContact C-N 3.35Å; M129-Q131 PolarHBondContact O-N 3.4Å; M129-R132 PolarHBondContact O-N 3.02Å; M129-L133 HydrophobicContact CG-CD1 3.73Å; M129-L133 HydrophobicContact CG-CG 4.44Å; M129-L133 WeakPolarHBondContact O-CB 3.48Å; M129-L133 VanDerWaalsContact O-CG 3.28Å; M129-L133 WeakPolarHBondContact O-CG 3.48Å; M129-L133 PolarHBondContact O-N 3.38Å; M129-L133 VanDerWaalsContact O-N 3.07Å; M129-L133 HydrophobicContact SD-CD1 3.8Å; M129-L133 HydrophobicContact SD-CG 4.09Å; M129-M295 HydrophobicContact CE-CG 4.31Å; M129-M295 HydrophobicContact CE-SD 3.91Å; M129-M295 HydrophobicContact SD-SD 4Å; M129-Q303 HydrophobicContact CE-CG 4.29Å; M129-Q303 HydrophobicContact SD-CG 3.84Å
130R93.4Very high90.5Very high36 Ų3644 Ų4414%0.13625%0.245CC..Hα-helixtrans-61.9-44.4176.5-177.759.9-178.7-135.4-3.1110.9L118 W126 K127 D128 L133 T134 N450L118-R130 HydrophobicContact CD1-CB 3.91Å; W126-R130 HydrophobicContact CZ2-CB 4.32Å; W126-R130 HydrophobicContact CZ2-CG 4.2Å; W126-R130 VanDerWaalsContact O-CB 3.3Å; W126-R130 WeakPolarHBondContact O-CB 3.45Å; W126-R130 PolarHBondContact O-N 3.04Å; K127-R130 PolarHBondContact O-N 3.17Å; D128-R130 PolarHBondContact O-N 2.76Å; R130-L133 PolarHBondContact O-N 3.28Å; R130-T134 WeakPolarHBondContact O-CB 3.45Å; R130-T134 PolarHBondContact O-N 3.47Å; R130-T134 PolarHBondContact O-OG1 3.1Å; R130-N450 PolarHBondContact NH1-O 3.22Å; R130-N450 PolarHBondContact NH2-O 3.01Å; R130-N450 PolarHBondContact NH2-OD1 3.48Å
131Q89.4Confident90.1Very high54 Ų5448.2 Ų48.225%0.25226%0.262SS..Hα-helixtrans-62.8-44.4177-74.2171.4-35.300111.5K127 D128 M129 L133 P135 L286K127-Q131 WeakPolarHBondContact O-CG 3.07Å; K127-Q131 PolarHBondContact O-N 3.43Å; D128-Q131 PolarHBondContact O-N 3.06Å; M129-Q131 VanDerWaalsContact C-N 3.35Å; M129-Q131 PolarHBondContact O-N 3.4Å; Q131-L133 VanDerWaalsContact C-N 3.32Å; Q131-L133 PolarHBondContact O-N 2.96Å; Q131-P135 VanDerWaalsContact O-CD 3.26Å; Q131-P135 WeakPolarHBondContact O-CD 3.45Å; Q131-L286 HydrophobicContact CB-CD1 4.26Å; Q131-L286 HydrophobicContact CG-CD1 4.42Å
132R85.3Confident89.9Confident29 Ų2948 Ų4811%0.10926%0.262CS..Hα-helixtrans-58.6-40.4176.6-70.6175.9-155.5-173.51.8113D128 M129 L278 I292 E293D128-R132 VanDerWaalsContact O-CG 3.3Å; D128-R132 WeakPolarHBondContact O-CG 3.41Å; D128-R132 PolarHBondContact O-N 2.96Å; M129-R132 PolarHBondContact O-N 3.02Å; R132-L278 HydrophobicContact CB-CD1 4.22Å; R132-I292 HydrophobicContact CG-CG2 4.49Å; R132-E293 PolarHBondContact NH1-O 3.03Å; R132-E293 PolarHBondContact NH2-O 3.15Å
133L88.6Confident89.7Confident0 Ų052.2 Ų52.20%028%0.278CS..Hα-helixtrans-90.1-23.1-171.1-64.8171.2000114L118 M129 R130 Q131 P135 T136 F271 L275 Q303 F307 I452L118-L133 HydrophobicContact CB-CD1 4.17Å; L118-L133 HydrophobicContact CD1-CD1 4.41Å; L118-L133 HydrophobicContact CD2-CD1 3.94Å; L118-L133 HydrophobicContact CG-CD1 4.39Å; M129-L133 HydrophobicContact CG-CD1 3.73Å; M129-L133 HydrophobicContact CG-CG 4.44Å; M129-L133 WeakPolarHBondContact O-CB 3.48Å; M129-L133 VanDerWaalsContact O-CG 3.28Å; M129-L133 WeakPolarHBondContact O-CG 3.48Å; M129-L133 PolarHBondContact O-N 3.38Å; M129-L133 VanDerWaalsContact O-N 3.07Å; M129-L133 HydrophobicContact SD-CD1 3.8Å; M129-L133 HydrophobicContact SD-CG 4.09Å; R130-L133 PolarHBondContact O-N 3.28Å; Q131-L133 VanDerWaalsContact C-N 3.32Å; Q131-L133 PolarHBondContact O-N 2.96Å; L133-P135 VanDerWaalsContact C-CD 3.47Å; L133-T136 VanDerWaalsContact O-CB 3.24Å; L133-T136 WeakPolarHBondContact O-CB 3.26Å; L133-T136 PolarHBondContact O-N 2.97Å; L133-T136 VanDerWaalsContact O-N 3.13Å; L133-T136 PolarHBondContact O-OG1 2.64Å; L133-F271 HydrophobicContact CD2-CE2 3.7Å; L133-F271 HydrophobicContact CD2-CZ 3.76Å; L133-L275 HydrophobicContact CD2-CD2 3.81Å; L133-Q303 HydrophobicContact CD1-CG 4.28Å; L133-F307 HydrophobicContact CD1-CE2 3.8Å; L133-F307 HydrophobicContact CD1-CZ 4.02Å; L133-F307 HydrophobicContact CD2-CE2 4.22Å; L133-I452 HydrophobicContact CB-CD1 3.72Å
134T90Very high89.3Confident63 Ų6355.8 Ų55.839%0.38728%0.284SS..G310 helixtrans-55.9-40.7-176.9-65.90000113.9R130 T136 F137R130-T134 WeakPolarHBondContact O-CB 3.45Å; R130-T134 PolarHBondContact O-N 3.47Å; R130-T134 PolarHBondContact O-OG1 3.1Å; T134-T136 PolarHBondContact O-N 2.86Å; T134-T136 VanDerWaalsContact O-N 3.1Å; T134-F137 PolarHBondContact O-N 2.68Å
135P86.3Confident89.1Confident72 Ų7250.4 Ų50.447%0.46826%0.262SS..G310 helixtrans-56.6-26.8177.6-28.836.9000114.9Q131 L133 F137 T138Q131-P135 VanDerWaalsContact O-CD 3.26Å; Q131-P135 WeakPolarHBondContact O-CD 3.45Å; L133-P135 VanDerWaalsContact C-CD 3.47Å; P135-F137 VanDerWaalsContact C-N 3.26Å; P135-F137 PolarHBondContact O-N 3.09Å; P135-T138 WeakPolarHBondContact O-CG2 3.48Å; P135-T138 PolarHBondContact O-OG1 3Å; P135-T138 VanDerWaalsContact O-OG1 3.09Å
136T83.6Confident89.2Confident12 Ų1245.7 Ų45.77%0.07424%0.241CC..G310 helixtrans-62.6-32.3176.1-35.50000112.7L133 T134 K141 F271 L274L133-T136 VanDerWaalsContact O-CB 3.24Å; L133-T136 WeakPolarHBondContact O-CB 3.26Å; L133-T136 PolarHBondContact O-N 2.97Å; L133-T136 VanDerWaalsContact O-N 3.13Å; L133-T136 PolarHBondContact O-OG1 2.64Å; T134-T136 PolarHBondContact O-N 2.86Å; T134-T136 VanDerWaalsContact O-N 3.1Å; T136-K141 WeakPolarHBondContact O-CB 3.32Å; T136-F271 HydrophobicContact CG2-CD2 3.47Å; T136-F271 VanDerWaalsContact CG2-CD2 3.47Å; T136-F271 HydrophobicContact CG2-CE2 4.08Å; T136-F271 HydrophobicContact CG2-CG 4.39Å; T136-L274 HydrophobicContact CG2-CD2 4Å; T136-L274 WeakPolarHBondContact OG1-CD2 3.13Å
137F87.3Confident89.1Confident21 Ų2148.8 Ų48.89%0.09226%0.263CS..G310 helixtrans-104.121.5-169.6-62.6-79.4000113.1T134 P135 M142 F307 I452 R455 F456T134-F137 PolarHBondContact O-N 2.68Å; P135-F137 VanDerWaalsContact C-N 3.26Å; P135-F137 PolarHBondContact O-N 3.09Å; F137-M142 HydrophobicContact CD1-CE 4.14Å; F137-F307 HydrophobicContact CE1-CE1 4.26Å; F137-F307 HydrophobicContact CE2-CD1 4.3Å; F137-F307 AromaticContact CE2-CE1 3.41Å; F137-F307 HydrophobicContact CE2-CE1 3.41Å; F137-F307 VanDerWaalsContact CE2-CE1 3.41Å; F137-F307 AromaticContact CE2-CZ 3.67Å; F137-F307 HydrophobicContact CE2-CZ 3.67Å; F137-F307 AromaticContact CZ-CD1 3.66Å; F137-F307 HydrophobicContact CZ-CD1 3.66Å; F137-F307 AromaticContact CZ-CE1 3.18Å; F137-F307 HydrophobicContact CZ-CE1 3.18Å; F137-F307 AromaticContact CZ-CZ 3.89Å; F137-F307 HydrophobicContact CZ-CZ 3.89Å; F137-I452 WeakPolarHBondContact CB-O 3.43Å; F137-I452 HydrophobicContact CD2-CD1 3.83Å; F137-I452 HydrophobicContact CD2-CG1 3.65Å; F137-I452 HydrophobicContact CD2-CG2 4.35Å; F137-I452 HydrophobicContact CE2-CD1 4.12Å; F137-I452 HydrophobicContact CE2-CG1 4.21Å; F137-I452 HydrophobicContact CE2-CG2 4.16Å; F137-I452 HydrophobicContact CG-CG1 4.28Å; F137-I452 WeakPolarHBondContact CG-O 3.31Å; F137-R455 PolarHBondContact O-NH1 2.9Å; F137-F456 HydrophobicContact CD1-CB 4.29Å; F137-F456 HydrophobicContact CE1-CB 4.32Å
138T89.2Confident89Confident59 Ų5946.6 Ų46.636%0.36226%0.258SS..SBendtrans-72.6156174.957.50000111.5P135 G140 K141 M142P135-T138 WeakPolarHBondContact O-CG2 3.48Å; P135-T138 PolarHBondContact O-OG1 3Å; P135-T138 VanDerWaalsContact O-OG1 3.09Å; T138-G140 PolarHBondContact O-N 2.88Å; T138-K141 PolarHBondContact O-N 3.08Å; T138-K141 WeakPolarHBondContact OG1-CG 3.16Å; T138-K141 PolarHBondContact OG1-N 2.96Å; T138-M142 WeakPolarHBondContact O-CG 3.22Å; T138-M142 PolarHBondContact O-N 3.43Å
139S88.1Confident89.2Confident63 Ų6345.8 Ų45.844%0.44125%0.253SS..Hα-helixtrans-57.7-36.1178.1-51.10000112.5M142 K143S139-M142 PolarHBondContact O-N 3.32Å; S139-K143 PolarHBondContact O-N 3.36Å
140G87.9Confident89.4Confident54 Ų5446.7 Ų46.756%0.55726%0.258SS*.Hα-helixtrans-62.3-42.6174.800000112.7T138 K143 F144T138-G140 PolarHBondContact O-N 2.88Å; G140-K143 PolarHBondContact O-N 2.94Å; G140-F144 WeakPolarHBondContact O-CB 3.34Å; G140-F144 PolarHBondContact O-N 3.46Å
141K86.1Confident89.5Confident107 Ų10751.5 Ų51.547%0.46528%0.28SS..Hα-helixtrans-70.5-32.1175.2-67.4-62.4-175.1-179.90112.8T136 T138 F144 M145T136-K141 WeakPolarHBondContact O-CB 3.32Å; T138-K141 PolarHBondContact O-N 3.08Å; T138-K141 WeakPolarHBondContact OG1-CG 3.16Å; T138-K141 PolarHBondContact OG1-N 2.96Å; K141-F144 PolarHBondContact O-N 3.28Å; K141-M145 WeakPolarHBondContact O-CG 3.22Å; K141-M145 PolarHBondContact O-N 2.99Å
142M90.6Very high89.8Confident2 Ų249.6 Ų49.61%0.0127%0.272CS..Hα-helixtrans-62.5-50.9171.4-64.5-54.397.600111F137 T138 S139 F144 M145 F146 Y353 R455 F456 M459F137-M142 HydrophobicContact CD1-CE 4.14Å; T138-M142 WeakPolarHBondContact O-CG 3.22Å; T138-M142 PolarHBondContact O-N 3.43Å; S139-M142 PolarHBondContact O-N 3.32Å; M142-F144 PolarHBondContact O-N 3.16Å; M142-M145 HydrophobicContact CE-CE 3.16Å; M142-M145 PolarHBondContact O-N 3.42Å; M142-M145 VanDerWaalsContact O-N 3.09Å; M142-M145 HydrophobicContact SD-CE 4.14Å; M142-F146 PolarHBondContact O-N 2.9Å; M142-Y353 HydrophobicContact CB-CE2 4.18Å; M142-R455 HydrophobicContact CG-CB 3.99Å; M142-R455 HydrophobicContact SD-CB 4.07Å; M142-F456 HydrophobicContact CE-CB 4.46Å; M142-F456 HydrophobicContact SD-CB 3.82Å; M142-F456 HydrophobicContact SD-CD2 4.25Å; M142-M459 HydrophobicContact CB-SD 4.24Å; M142-M459 HydrophobicContact SD-CE 4.1Å
143K89.5Confident90.3Very high117 Ų11748.2 Ų48.251%0.50927%0.267SS..Hα-helixtrans-58.5-35.4176.9-171.7168.7-176.31630111.9S139 G140 F146 Y353 E354S139-K143 PolarHBondContact O-N 3.36Å; G140-K143 PolarHBondContact O-N 2.94Å; K143-F146 WeakPolarHBondContact O-CB 3.27Å; K143-Y353 HydrophobicContact CB-CD2 4.18Å; K143-Y353 HydrophobicContact CB-CE2 4.23Å; K143-Y353 HydrophobicContact CB-CG 4.46Å; K143-Y353 HydrophobicContact CG-CD2 4.35Å; K143-Y353 HydrophobicContact CG-CG 4.23Å; K143-E354 IonicContact NZ-OE1 3.11Å
144F86Confident90.6Very high109 Ų10953 Ų5348%0.47829%0.289SS..Hα-helixtrans-67.3-40.6175-176.9-92.1000113.5G140 K141 M142 F146 P147 N269G140-F144 WeakPolarHBondContact O-CB 3.34Å; G140-F144 PolarHBondContact O-N 3.46Å; K141-F144 PolarHBondContact O-N 3.28Å; M142-F144 PolarHBondContact O-N 3.16Å; F144-F146 VanDerWaalsContact C-N 3.35Å; F144-P147 WeakPolarHBondContact O-CD 3.49Å; F144-N269 HydrophobicContact CE1-CB 3.47Å; F144-N269 VanDerWaalsContact CE1-CB 3.47Å; F144-N269 WeakPolarHBondContact CE1-O 3.33Å; F144-N269 HydrophobicContact CZ-CB 3.44Å; F144-N269 VanDerWaalsContact CZ-CB 3.44Å
145M89.4Confident90.9Very high21 Ų2152.2 Ų52.210%0.10328%0.281CS..Hα-helixtrans-78-20.4178.2-71.4-174.6-7200113.3K141 M142 P147 T148 V149 C190 F456K141-M145 WeakPolarHBondContact O-CG 3.22Å; K141-M145 PolarHBondContact O-N 2.99Å; M142-M145 HydrophobicContact CE-CE 3.16Å; M142-M145 PolarHBondContact O-N 3.42Å; M142-M145 VanDerWaalsContact O-N 3.09Å; M142-M145 HydrophobicContact SD-CE 4.14Å; M145-P147 VanDerWaalsContact C-CD 3.49Å; M145-T148 VanDerWaalsContact O-CB 3.31Å; M145-T148 WeakPolarHBondContact O-CB 3.45Å; M145-T148 PolarHBondContact O-N 2.69Å; M145-V149 PolarHBondContact O-N 3.26Å; M145-C190 HydrophobicContact SD-CB 4.05Å; M145-F456 HydrophobicContact CE-CD2 3.96Å; M145-F456 HydrophobicContact CE-CE2 4.29Å; M145-F456 HydrophobicContact SD-CD2 4.45Å; M145-F456 HydrophobicContact SD-CE2 4.2Å
146F92.4Very high91.4Very high13 Ų1348.8 Ų48.86%0.05726%0.259CS..Hα-helixtrans-49.4-46.8-174.8-173.4-87.9000114.3M142 K143 F144 T148 V149 I150 L351 T352 Y353 I356 M459 I463M142-F146 PolarHBondContact O-N 2.9Å; K143-F146 WeakPolarHBondContact O-CB 3.27Å; F144-F146 VanDerWaalsContact C-N 3.35Å; F146-T148 PolarHBondContact O-N 2.96Å; F146-V149 WeakPolarHBondContact O-CB 3.3Å; F146-V149 PolarHBondContact O-N 2.67Å; F146-V149 VanDerWaalsContact O-N 3.07Å; F146-I150 HydrophobicContact CD1-CG1 3.78Å; F146-I150 HydrophobicContact CE1-CD1 3.75Å; F146-I150 HydrophobicContact CE1-CG1 3.4Å; F146-I150 VanDerWaalsContact CE1-CG1 3.4Å; F146-I150 HydrophobicContact CZ-CD1 3.77Å; F146-I150 HydrophobicContact CZ-CG1 3.94Å; F146-I150 WeakPolarHBondContact O-CG1 3.33Å; F146-I150 PolarHBondContact O-N 3.49Å; F146-L351 WeakPolarHBondContact CE1-O 3.34Å; F146-L351 WeakPolarHBondContact CZ-O 3.49Å; F146-T352 WeakPolarHBondContact CZ-O 3.43Å; F146-Y353 HydrophobicContact CB-CD2 4.21Å; F146-Y353 AromaticContact CD2-CD2 3.62Å; F146-Y353 HydrophobicContact CD2-CD2 3.62Å; F146-Y353 HydrophobicContact CD2-CE2 4.48Å; F146-Y353 HydrophobicContact CD2-CG 4.41Å; F146-Y353 HydrophobicContact CE2-CD2 4.19Å; F146-Y353 HydrophobicContact CG-CD2 4.02Å; F146-I356 HydrophobicContact CE2-CB 4.44Å; F146-I356 HydrophobicContact CE2-CG1 3.99Å; F146-I356 HydrophobicContact CZ-CG1 4.04Å; F146-M459 HydrophobicContact CB-SD 4.23Å; F146-M459 HydrophobicContact CD2-CG 4.12Å; F146-M459 HydrophobicContact CD2-SD 3.86Å; F146-I463 HydrophobicContact CD2-CD1 3.89Å; F146-I463 HydrophobicContact CE2-CD1 3.58Å; F146-I463 HydrophobicContact CE2-CG1 4.1Å; F146-I463 HydrophobicContact CZ-CD1 4.2Å
147P92.6Very high91.9Very high82 Ų8249 Ų4953%0.53226%0.26SS..Hα-helixtrans-61.1-31.9178.5-23.135.1000113.7F144 M145 I150 K151F144-P147 WeakPolarHBondContact O-CD 3.49Å; M145-P147 VanDerWaalsContact C-CD 3.49Å; P147-I150 PolarHBondContact O-N 2.95Å; P147-K151 PolarHBondContact O-N 2.99Å
148T91.8Very high92.3Very high45 Ų4553 Ų5328%0.27628%0.277SS..Hα-helixtrans-67.8-42.1176.4-58.40000110.6M145 F146 I150 K151 V152 T189 C190M145-T148 VanDerWaalsContact O-CB 3.31Å; M145-T148 WeakPolarHBondContact O-CB 3.45Å; M145-T148 PolarHBondContact O-N 2.69Å; F146-T148 PolarHBondContact O-N 2.96Å; T148-I150 VanDerWaalsContact C-N 3.33Å; T148-K151 PolarHBondContact O-N 3.36Å; T148-V152 WeakPolarHBondContact O-CG2 3.34Å; T148-V152 PolarHBondContact O-N 3.32Å; T148-V152 VanDerWaalsContact O-N 3.13Å; T148-T189 HydrophobicContact CG2-CG2 3.36Å; T148-C190 VanDerWaalsContact CG2-SG 3.56Å
149V94.7Very high92.6Very high0 Ų050.4 Ų50.40%026%0.261CS..Hα-helixtrans-64.7-41176.9-172.30000110.4M145 F146 V152 S153 V186 M459 Q460 I463M145-V149 PolarHBondContact O-N 3.26Å; F146-V149 WeakPolarHBondContact O-CB 3.3Å; F146-V149 PolarHBondContact O-N 2.67Å; F146-V149 VanDerWaalsContact O-N 3.07Å; V149-V152 PolarHBondContact O-N 2.88Å; V149-S153 WeakPolarHBondContact O-CB 3.34Å; V149-S153 PolarHBondContact O-N 3.11Å; V149-V186 HydrophobicContact CG1-CG1 4.27Å; V149-V186 HydrophobicContact CG1-CG2 4.16Å; V149-V186 HydrophobicContact CG2-CG1 4.15Å; V149-M459 HydrophobicContact CG2-CE 3.93Å; V149-Q460 HydrophobicContact CG1-CB 4.32Å; V149-I463 HydrophobicContact CB-CD1 3.96Å; V149-I463 HydrophobicContact CG1-CB 4.41Å; V149-I463 HydrophobicContact CG1-CD1 3.51Å; V149-I463 HydrophobicContact CG1-CG2 4.31Å
150I95.6Very high92.9Very high22 Ų2247.6 Ų47.611%0.11324%0.241CC..Hα-helixtrans-59.4-49174.8-67.5-61.6000111.1F146 P147 T148 V152 S153 E154 L351 I463F146-I150 HydrophobicContact CD1-CG1 3.78Å; F146-I150 HydrophobicContact CE1-CD1 3.75Å; F146-I150 HydrophobicContact CE1-CG1 3.4Å; F146-I150 VanDerWaalsContact CE1-CG1 3.4Å; F146-I150 HydrophobicContact CZ-CD1 3.77Å; F146-I150 HydrophobicContact CZ-CG1 3.94Å; F146-I150 WeakPolarHBondContact O-CG1 3.33Å; F146-I150 PolarHBondContact O-N 3.49Å; P147-I150 PolarHBondContact O-N 2.95Å; T148-I150 VanDerWaalsContact C-N 3.33Å; I150-V152 VanDerWaalsContact C-N 3.32Å; I150-V152 PolarHBondContact O-N 3.34Å; I150-S153 WeakPolarHBondContact CA-OG 3.4Å; I150-S153 CarbonylContact O-C 3.56Å; I150-S153 WeakPolarHBondContact O-CA 3.39Å; I150-S153 WeakPolarHBondContact O-CB 3.4Å; I150-S153 PolarHBondContact O-N 3.06Å; I150-S153 PolarHBondContact O-OG 3.21Å; I150-E154 HydrophobicContact CG2-CG 4.36Å; I150-E154 WeakPolarHBondContact O-CG 3.45Å; I150-E154 PolarHBondContact O-N 3.09Å; I150-L351 HydrophobicContact CD1-CB 3.73Å; I150-L351 HydrophobicContact CD1-CD1 4.48Å; I150-L351 WeakPolarHBondContact CD1-O 3.23Å; I150-I463 HydrophobicContact CD1-CD1 4.18Å; I150-I463 HydrophobicContact CD1-CG1 4.29Å; I150-I463 HydrophobicContact CD1-CG2 3.99Å
151K94.6Very high93.2Very high137 Ų13747 Ų4760%0.59623%0.227SC*.Hα-helixtrans-55.4-45.1177.2-174.6-175.7178.3-170.40112.4P147 T148 S153 E154 E155P147-K151 PolarHBondContact O-N 2.99Å; T148-K151 PolarHBondContact O-N 3.36Å; K151-S153 VanDerWaalsContact C-N 3.3Å; K151-S153 PolarHBondContact O-N 2.92Å; K151-E154 PolarHBondContact O-N 3.22Å; K151-E155 PolarHBondContact O-N 3.39Å
152V96.1Very high93.5Very high14 Ų1447.6 Ų47.69%0.08523%0.231CC..Hα-helixtrans-65.7-36.9176.11790000110.9T148 V149 I150 E155 F156 F182 D185 V186 L199T148-V152 WeakPolarHBondContact O-CG2 3.34Å; T148-V152 PolarHBondContact O-N 3.32Å; T148-V152 VanDerWaalsContact O-N 3.13Å; V149-V152 PolarHBondContact O-N 2.88Å; I150-V152 VanDerWaalsContact C-N 3.32Å; I150-V152 PolarHBondContact O-N 3.34Å; V152-E155 PolarHBondContact O-N 3.16Å; V152-F156 WeakPolarHBondContact O-CB 3.41Å; V152-F156 PolarHBondContact O-N 2.91Å; V152-F182 HydrophobicContact CB-CE2 4.49Å; V152-F182 HydrophobicContact CG1-CD2 3.9Å; V152-F182 HydrophobicContact CG1-CE2 3.99Å; V152-D185 HydrophobicContact CG1-CB 3.72Å; V152-V186 HydrophobicContact CB-CG2 4.04Å; V152-V186 HydrophobicContact CG1-CG2 3.75Å; V152-L199 HydrophobicContact CG1-CD1 4.03Å
153S96.3Very high93.5Very high0 Ų051.2 Ų51.20%025%0.248CC..Hα-helixtrans-69.4-32.4178.983.90000113.8V149 I150 K151 F156 V157 Q467V149-S153 WeakPolarHBondContact O-CB 3.34Å; V149-S153 PolarHBondContact O-N 3.11Å; I150-S153 WeakPolarHBondContact CA-OG 3.4Å; I150-S153 CarbonylContact O-C 3.56Å; I150-S153 WeakPolarHBondContact O-CA 3.39Å; I150-S153 WeakPolarHBondContact O-CB 3.4Å; I150-S153 PolarHBondContact O-N 3.06Å; I150-S153 PolarHBondContact O-OG 3.21Å; K151-S153 VanDerWaalsContact C-N 3.3Å; K151-S153 PolarHBondContact O-N 2.92Å; S153-F156 WeakPolarHBondContact O-CB 3.49Å; S153-F156 PolarHBondContact O-N 2.84Å; S153-V157 WeakPolarHBondContact O-CG2 3.31Å; S153-V157 PolarHBondContact O-N 2.97Å; S153-Q467 PolarHBondContact OG-NE2 3.47Å
154E95.2Very high93.5Very high99 Ų9945.7 Ų45.746%0.46322%0.224SC..Hα-helixtrans-66.9-43.2173.1-70.6169.7173.100110.7I150 K151 F156 V157 K158I150-E154 HydrophobicContact CG2-CG 4.36Å; I150-E154 WeakPolarHBondContact O-CG 3.45Å; I150-E154 PolarHBondContact O-N 3.09Å; K151-E154 PolarHBondContact O-N 3.22Å; E154-F156 VanDerWaalsContact C-N 3.28Å; E154-F156 PolarHBondContact O-N 2.72Å; E154-V157 PolarHBondContact O-N 3.13Å; E154-K158 WeakPolarHBondContact O-CG 3.45Å; E154-K158 PolarHBondContact O-N 3.23Å
155E95.9Very high93.2Very high48 Ų4843.9 Ų43.922%0.22422%0.223CC..Hα-helixtrans-63.6-39.3174.6-166.758.1-15600111.6K151 V152 V157 K158 V159 R200K151-E155 PolarHBondContact O-N 3.39Å; V152-E155 PolarHBondContact O-N 3.16Å; E155-V157 PolarHBondContact O-N 3.36Å; E155-K158 WeakPolarHBondContact O-CB 3.41Å; E155-K158 PolarHBondContact O-N 3.26Å; E155-K158 WeakPolarHBondContact OE2-CD 3.27Å; E155-K158 IonicContact OE2-NZ 2.91Å; E155-K158 PolarHBondContact OE2-NZ 2.9Å; E155-V159 WeakPolarHBondContact O-CG2 3.24Å; E155-V159 PolarHBondContact O-N 3.44Å; E155-R200 IonicContact OE1-CZ 3.77Å; E155-R200 IonicContact OE1-NE 3.33Å; E155-R200 PolarHBondContact OE1-NE 3.34Å; E155-R200 IonicContact OE1-NH2 3.53Å; E155-R200 PolarHBondContact OE1-NH2 2.97Å
156F96.3Very high92.4Very high0 Ų047.1 Ų47.10%025%0.253CS..Hα-helixtrans-58.8-46.4174.2172.9-128.7000112.3V152 S153 E154 K158 V159 I160 L178 M179 F182 L199 I468V152-F156 WeakPolarHBondContact O-CB 3.41Å; V152-F156 PolarHBondContact O-N 2.91Å; S153-F156 WeakPolarHBondContact O-CB 3.49Å; S153-F156 PolarHBondContact O-N 2.84Å; E154-F156 VanDerWaalsContact C-N 3.28Å; E154-F156 PolarHBondContact O-N 2.72Å; F156-K158 PolarHBondContact O-N 3.37Å; F156-V159 PolarHBondContact O-N 3.41Å; F156-I160 HydrophobicContact CD1-CD1 4.37Å; F156-I160 HydrophobicContact CD2-CD1 4.02Å; F156-I160 HydrophobicContact CD2-CG1 4.19Å; F156-I160 HydrophobicContact CE1-CD1 3.75Å; F156-I160 HydrophobicContact CE2-CD1 3.29Å; F156-I160 HydrophobicContact CE2-CG1 3.62Å; F156-I160 HydrophobicContact CG-CD1 4.47Å; F156-I160 HydrophobicContact CZ-CD1 3.11Å; F156-I160 HydrophobicContact CZ-CG1 3.98Å; F156-I160 WeakPolarHBondContact O-CG1 3.38Å; F156-I160 PolarHBondContact O-N 2.91Å; F156-L178 HydrophobicContact CD2-CD1 4.31Å; F156-L178 HydrophobicContact CE2-CD1 3.68Å; F156-L178 HydrophobicContact CE2-CD2 3.85Å; F156-L178 HydrophobicContact CE2-CG 3.53Å; F156-L178 HydrophobicContact CZ-CD2 4.18Å; F156-L178 HydrophobicContact CZ-CG 4.17Å; F156-M179 HydrophobicContact CE1-CE 3.79Å; F156-M179 HydrophobicContact CE2-CE 3.87Å; F156-M179 HydrophobicContact CZ-CE 3.13Å; F156-F182 HydrophobicContact CB-CD2 3.79Å; F156-F182 HydrophobicContact CB-CE2 4.35Å; F156-F182 AromaticContact CD1-CD2 3.94Å; F156-F182 HydrophobicContact CD1-CD2 3.94Å; F156-F182 HydrophobicContact CD1-CE2 4.33Å; F156-F182 HydrophobicContact CD1-CG 4.11Å; F156-F182 HydrophobicContact CD2-CB 4.17Å; F156-F182 HydrophobicContact CG-CB 4.21Å; F156-F182 AromaticContact CG-CD2 3.83Å; F156-F182 HydrophobicContact CG-CD2 3.83Å; F156-F182 HydrophobicContact CG-CG 4.13Å; F156-L199 HydrophobicContact CB-CD1 3.89Å; F156-L199 HydrophobicContact CB-CD2 4.33Å; F156-L199 HydrophobicContact CD2-CD2 3.71Å; F156-L199 HydrophobicContact CG-CD2 4.42Å; F156-I468 HydrophobicContact CE1-CD1 3.77Å; F156-I468 HydrophobicContact CE1-CG1 3.73Å; F156-I468 HydrophobicContact CZ-CD1 3.75Å; F156-I468 HydrophobicContact CZ-CG1 3.95Å
157V95.3Very high91Very high15 Ų1549.9 Ų49.99%0.09128%0.279CS..Hα-helixtrans-61.2-42.4174.7169.80000111.7S153 E154 E155 V159 I160 T161 Q467 F472S153-V157 WeakPolarHBondContact O-CG2 3.31Å; S153-V157 PolarHBondContact O-N 2.97Å; E154-V157 PolarHBondContact O-N 3.13Å; E155-V157 PolarHBondContact O-N 3.36Å; V157-V159 VanDerWaalsContact C-N 3.34Å; V157-V159 PolarHBondContact O-N 3.08Å; V157-I160 PolarHBondContact O-N 2.91Å; V157-T161 VanDerWaalsContact O-CB 3.3Å; V157-T161 WeakPolarHBondContact O-CB 3.29Å; V157-T161 PolarHBondContact O-N 3.08Å; V157-T161 PolarHBondContact O-OG1 3.42Å; V157-Q467 HydrophobicContact CG2-CB 3.72Å; V157-Q467 HydrophobicContact CG2-CG 4.21Å; V157-F472 HydrophobicContact CG1-CE2 4.48Å
158K95.4Very high89.6Confident107 Ų10755.1 Ų55.147%0.46530%0.296SS..Hα-helixtrans-59.8-45.7177-68.8173.4-162.5163.40111.4E154 E155 F156 I160 T161 E162E154-K158 WeakPolarHBondContact O-CG 3.45Å; E154-K158 PolarHBondContact O-N 3.23Å; E155-K158 WeakPolarHBondContact O-CB 3.41Å; E155-K158 PolarHBondContact O-N 3.26Å; E155-K158 WeakPolarHBondContact OE2-CD 3.27Å; E155-K158 IonicContact OE2-NZ 2.91Å; E155-K158 PolarHBondContact OE2-NZ 2.9Å; F156-K158 PolarHBondContact O-N 3.37Å; K158-I160 PolarHBondContact O-N 3.48Å; K158-T161 WeakPolarHBondContact O-CB 3.28Å; K158-T161 PolarHBondContact O-N 3.06Å; K158-E162 VanDerWaalsContact O-CG 3.31Å; K158-E162 WeakPolarHBondContact O-CG 3.41Å; K158-E162 PolarHBondContact O-N 3.44Å
159V94.8Very high88.8Confident4 Ų458.5 Ų58.52%0.02431%0.313CS..Hα-helixtrans-62.4-42.2178.6168.90000111.9E155 F156 V157 E162 Q163 L199 R200E155-V159 WeakPolarHBondContact O-CG2 3.24Å; E155-V159 PolarHBondContact O-N 3.44Å; F156-V159 PolarHBondContact O-N 3.41Å; V157-V159 VanDerWaalsContact C-N 3.34Å; V157-V159 PolarHBondContact O-N 3.08Å; V159-E162 PolarHBondContact O-N 2.85Å; V159-Q163 WeakPolarHBondContact O-CG 3.49Å; V159-Q163 PolarHBondContact O-N 2.74Å; V159-Q163 VanDerWaalsContact O-N 3.16Å; V159-L199 WeakPolarHBondContact CG1-O 3.17Å; V159-L199 HydrophobicContact CG2-CB 4.34Å; V159-R200 HydrophobicContact CG2-CG 4.1Å
160I94.9Very high88.5Confident3 Ų359.5 Ų59.52%0.01532%0.323CS..Hα-helixtrans-64-45.3174.4-62.4167.3000110.3F156 V157 K158 E162 Q163 V164 L173 L178 I468 F472 V503F156-I160 HydrophobicContact CD1-CD1 4.37Å; F156-I160 HydrophobicContact CD2-CD1 4.02Å; F156-I160 HydrophobicContact CD2-CG1 4.19Å; F156-I160 HydrophobicContact CE1-CD1 3.75Å; F156-I160 HydrophobicContact CE2-CD1 3.29Å; F156-I160 HydrophobicContact CE2-CG1 3.62Å; F156-I160 HydrophobicContact CG-CD1 4.47Å; F156-I160 HydrophobicContact CZ-CD1 3.11Å; F156-I160 HydrophobicContact CZ-CG1 3.98Å; F156-I160 WeakPolarHBondContact O-CG1 3.38Å; F156-I160 PolarHBondContact O-N 2.91Å; V157-I160 PolarHBondContact O-N 2.91Å; K158-I160 PolarHBondContact O-N 3.48Å; I160-E162 VanDerWaalsContact C-N 3.34Å; I160-E162 PolarHBondContact O-N 2.69Å; I160-Q163 CarbonylContact O-C 3.56Å; I160-Q163 PolarHBondContact O-N 2.79Å; I160-V164 HydrophobicContact CG2-CG2 3.8Å; I160-V164 WeakPolarHBondContact O-CB 3.36Å; I160-V164 WeakPolarHBondContact O-CG2 3.08Å; I160-V164 PolarHBondContact O-N 2.72Å; I160-L173 HydrophobicContact CG2-CD1 4.22Å; I160-L178 HydrophobicContact CD1-CD2 4.2Å; I160-L178 HydrophobicContact CG1-CD1 4.45Å; I160-L178 HydrophobicContact CG1-CD2 3.89Å; I160-I468 HydrophobicContact CD1-CG1 4.06Å; I160-F472 HydrophobicContact CB-CE1 4.47Å; I160-F472 HydrophobicContact CB-CE2 4.22Å; I160-F472 HydrophobicContact CB-CZ 3.9Å; I160-F472 HydrophobicContact CD1-CE2 4.46Å; I160-F472 HydrophobicContact CG2-CD1 4.11Å; I160-F472 HydrophobicContact CG2-CD2 4.34Å; I160-F472 HydrophobicContact CG2-CE1 3.59Å; I160-F472 HydrophobicContact CG2-CE2 3.88Å; I160-F472 HydrophobicContact CG2-CG 4.46Å; I160-F472 HydrophobicContact CG2-CZ 3.47Å; I160-F472 VanDerWaalsContact CG2-CZ 3.47Å; I160-V503 HydrophobicContact CG2-CG1 4.3Å
161T93.8Very high88.4Confident42 Ų4259.3 Ų59.326%0.25833%0.325SS..Hα-helixtrans-55.4-51.4178.4-57.80000109.4V157 K158 Q163 V164 R505V157-T161 VanDerWaalsContact O-CB 3.3Å; V157-T161 WeakPolarHBondContact O-CB 3.29Å; V157-T161 PolarHBondContact O-N 3.08Å; V157-T161 PolarHBondContact O-OG1 3.42Å; K158-T161 WeakPolarHBondContact O-CB 3.28Å; K158-T161 PolarHBondContact O-N 3.06Å; T161-Q163 PolarHBondContact O-N 3.33Å; T161-V164 CarbonylContact O-C 3.53Å; T161-V164 PolarHBondContact O-N 3.31Å; T161-R505 VanDerWaalsContact CG2-NH2 3.32Å; T161-R505 PolarHBondContact O-NH2 3.08Å
162E92.3Very high88.5Confident120 Ų12055.9 Ų55.956%0.56132%0.315SS*.Hα-helixtrans-55.5-35.2176.1-70.5165.9-155.500113.4K158 V159 I160 R200K158-E162 VanDerWaalsContact O-CG 3.31Å; K158-E162 WeakPolarHBondContact O-CG 3.41Å; K158-E162 PolarHBondContact O-N 3.44Å; V159-E162 PolarHBondContact O-N 2.85Å; I160-E162 VanDerWaalsContact C-N 3.34Å; I160-E162 PolarHBondContact O-N 2.69Å; E162-R200 IonicContact OE1-CZ 2.8Å; E162-R200 IonicContact OE1-NH1 3.3Å; E162-R200 PolarHBondContact OE1-NH1 2.85Å; E162-R200 IonicContact OE1-NH2 3.23Å; E162-R200 PolarHBondContact OE1-NH2 2.75Å; E162-R200 IonicContact OE2-CZ 3.27Å; E162-R200 IonicContact OE2-NH1 2.83Å; E162-R200 PolarHBondContact OE2-NH1 3.48Å; E162-R200 IonicContact OE2-NH2 2.78Å
163Q90.8Very high88.5Confident78 Ų7855.9 Ų55.936%0.36431%0.314SS..Hα-helixtrans-85.2-20.3-179.6-70.3177.538.200114.8V159 I160 T161 P165 A171 L173V159-Q163 WeakPolarHBondContact O-CG 3.49Å; V159-Q163 PolarHBondContact O-N 2.74Å; V159-Q163 VanDerWaalsContact O-N 3.16Å; I160-Q163 CarbonylContact O-C 3.56Å; I160-Q163 PolarHBondContact O-N 2.79Å; T161-Q163 PolarHBondContact O-N 3.33Å; Q163-P165 WeakPolarHBondContact O-CD 3.41Å; Q163-A171 WeakPolarHBondContact O-CB 3.42Å; Q163-L173 HydrophobicContact CB-CD2 4.15Å
164V90.4Very high88.5Confident0 Ų058 Ų580%032%0.324CS..SBendtrans-109.496.6-178.9-178.40000108.1I160 T161 A171 L173 F472 V503 R505I160-V164 HydrophobicContact CG2-CG2 3.8Å; I160-V164 WeakPolarHBondContact O-CB 3.36Å; I160-V164 WeakPolarHBondContact O-CG2 3.08Å; I160-V164 PolarHBondContact O-N 2.72Å; T161-V164 CarbonylContact O-C 3.53Å; T161-V164 PolarHBondContact O-N 3.31Å; V164-A171 HydrophobicContact CG2-CB 4.21Å; V164-L173 HydrophobicContact CG2-CD1 3.91Å; V164-F472 HydrophobicContact CB-CE1 4.44Å; V164-V503 WeakPolarHBondContact CG1-O 3.1Å; V164-V503 HydrophobicContact CG2-CB 4.04Å; V164-V503 HydrophobicContact CG2-CG1 4Å; V164-R505 HydrophobicContact CG1-CG 4.01Å; V164-R505 PolarHBondContact O-NE 3.19Å; V164-R505 PolarHBondContact O-NH2 3.05Å
165P78.1Confident88.5Confident71 Ų7153.5 Ų53.546%0.46130%0.303SS..  trans-60.6153.4177.4-20.532.8000111.1Q163 A167Q163-P165 WeakPolarHBondContact O-CD 3.41Å; P165-A167 HydrophobicContact CB-CB 4.35Å; P165-A167 PolarHBondContact O-N 2.96Å; P165-A167 VanDerWaalsContact O-N 3.08Å
166A72.9Confident88.4Confident89 Ų8953 Ų5374%0.73630%0.3SS*.SBendtrans-703.6172.100000113.8
167A63.7Low88.3Confident71 Ų7155.6 Ų55.659%0.58731%0.312SS*.SBendtrans-74.1150.7178.300000111.3P165 N169 G170P165-A167 HydrophobicContact CB-CB 4.35Å; P165-A167 PolarHBondContact O-N 2.96Å; P165-A167 VanDerWaalsContact O-N 3.08Å; A167-N169 PolarHBondContact O-N 3.19Å; A167-G170 PolarHBondContact O-N 2.73Å
168Q62.4Low88.3Confident193 Ų19355.2 Ų55.290%0.90231%0.31SS*.THydrogen-bonded Turntrans-54.4-9.1-155.3-80.9174.9-16.400118.9
169N75.5Confident88.4Confident116 Ų11650.1 Ų50.162%0.6229%0.288SS*.THydrogen-bonded Turntrans-124.310.4-173.4-65.8-13.6000114.6A167 R502A167-N169 PolarHBondContact O-N 3.19Å; N169-R502 PolarHBondContact O-NH1 3.45Å
170G88.1Confident88.3Confident21 Ų2150.1 Ų50.122%0.21629%0.288CS..  trans60.9-155.7-179.100000113.6A167 V503A167-G170 PolarHBondContact O-N 2.73Å; G170-V503 CarbonylContact C-O 3.52Å; G170-V503 WeakPolarHBondContact CA-O 3.42Å
171A93.9Very high88.3Confident18 Ų1850.9 Ų50.915%0.14929%0.291CS..EExtended strand (participates in β ladder)trans-135.5149.5176.200000111.7Q163 V164 L173 V503Q163-A171 WeakPolarHBondContact O-CB 3.42Å; V164-A171 HydrophobicContact CG2-CB 4.21Å; A171-L173 HydrophobicContact CB-CD2 4.26Å; A171-V503 PolarHBondContact N-O 2.91Å; A171-V503 PolarHBondContact O-N 2.87Å
172V95.5Very high88.4Confident65 Ų6548.9 Ų48.939%0.39428%0.279SS..EExtended strand (participates in β ladder)trans-86.4119.5171.4176.90000108.5C477 Y500 L501V172-C477 HydrophobicContact CG2-CB 4.13Å; V172-Y500 HydrophobicContact CG1-CD1 4.38Å; V172-L501 WeakPolarHBondContact CA-O 3.27Å
173L96.1Very high88.5Confident14 Ų1443.2 Ų43.27%0.07325%0.252CS..EExtended strand (participates in β ladder)trans-117.2145.5-179.4-56.7-174.5000110.7I160 Q163 V164 A171 I175 L178 Y500 L501 V503I160-L173 HydrophobicContact CG2-CD1 4.22Å; Q163-L173 HydrophobicContact CB-CD2 4.15Å; V164-L173 HydrophobicContact CG2-CD1 3.91Å; A171-L173 HydrophobicContact CB-CD2 4.26Å; L173-I175 HydrophobicContact CB-CD1 4.12Å; L173-I175 PolarHBondContact O-N 2.64Å; L173-L178 HydrophobicContact CD1-CD2 4.19Å; L173-Y500 WeakPolarHBondContact O-CA 3.16Å; L173-L501 PolarHBondContact N-O 2.85Å; L173-L501 PolarHBondContact O-N 2.71Å; L173-L501 VanDerWaalsContact O-N 3.09Å; L173-V503 HydrophobicContact CB-CG2 4.28Å; L173-V503 HydrophobicContact CD1-CB 4.19Å; L173-V503 HydrophobicContact CD1-CG2 3.9Å; L173-V503 HydrophobicContact CG-CB 4.48Å; L173-V503 HydrophobicContact CG-CG2 4.09Å
174E96.4Very high88.7Confident45 Ų4539.5 Ų39.521%0.2124%0.235CC..EExtended strand (participates in β ladder)trans-82.5100.3167.4-154.3-70106.700108.5K176 E177 L178 G498 I499 Y500E174-K176 PolarHBondContact O-N 3.44Å; E174-K176 WeakPolarHBondContact OE1-CA 3.21Å; E174-K176 WeakPolarHBondContact OE1-CB 3.48Å; E174-K176 PolarHBondContact OE1-N 3.02Å; E174-E177 HydrophobicContact CB-CB 4.48Å; E174-E177 WeakPolarHBondContact OE2-CA 3.32Å; E174-E177 WeakPolarHBondContact OE2-CB 3.23Å; E174-E177 PolarHBondContact OE2-N 2.75Å; E174-L178 WeakPolarHBondContact O-CB 3.28Å; E174-L178 PolarHBondContact O-N 3.04Å; E174-G498 WeakPolarHBondContact OE1-CA 3.44Å; E174-I499 PolarHBondContact OE1-N 2.83Å; E174-Y500 HydrophobicContact CB-CD1 3.94Å; E174-Y500 HydrophobicContact CB-CE1 3.6Å; E174-Y500 HydrophobicContact CG-CD1 3.99Å; E174-Y500 HydrophobicContact CG-CD2 4.42Å; E174-Y500 HydrophobicContact CG-CE1 3.49Å; E174-Y500 VanDerWaalsContact CG-CE1 3.49Å; E174-Y500 HydrophobicContact CG-CE2 3.96Å; E174-Y500 HydrophobicContact CG-CG 4.42Å; E174-Y500 VanDerWaalsContact CG-CZ 3.47Å
175I96.8Very high88.8Confident4 Ų439.9 Ų39.92%0.02124%0.237CC..Hα-helixtrans-69.1-35-169.4-60.3-61.8000111.4L173 L178 M179 L323 I499 L501 V503L173-I175 HydrophobicContact CB-CD1 4.12Å; L173-I175 PolarHBondContact O-N 2.64Å; I175-L178 PolarHBondContact O-N 3.17Å; I175-M179 HydrophobicContact CG2-CG 3.99Å; I175-M179 WeakPolarHBondContact O-CB 3.22Å; I175-M179 WeakPolarHBondContact O-CG 3.34Å; I175-M179 PolarHBondContact O-N 3.12Å; I175-L323 HydrophobicContact CG2-CB 4.23Å; I175-L323 HydrophobicContact CG2-CD1 3.5Å; I175-L323 VanDerWaalsContact CG2-CD1 3.5Å; I175-I499 WeakPolarHBondContact CB-O 3.47Å; I175-I499 PolarHBondContact N-O 2.75Å; I175-L501 HydrophobicContact CD1-CB 4.26Å; I175-L501 HydrophobicContact CG1-CB 3.8Å; I175-L501 HydrophobicContact CG1-CD1 3.85Å; I175-L501 HydrophobicContact CG1-CG 3.83Å; I175-V503 HydrophobicContact CD1-CG2 3.99Å
176K94.1Very high89.6Confident37 Ų3736.5 Ų36.516%0.16122%0.215CC..Hα-helixtrans-65.9-46.4-178-171.6-179.7175.4-179.50111.7E174 L178 M179 A180 E313 S320E174-K176 PolarHBondContact O-N 3.44Å; E174-K176 WeakPolarHBondContact OE1-CA 3.21Å; E174-K176 WeakPolarHBondContact OE1-CB 3.48Å; E174-K176 PolarHBondContact OE1-N 3.02Å; K176-L178 VanDerWaalsContact C-N 3.33Å; K176-L178 PolarHBondContact O-N 3.46Å; K176-M179 PolarHBondContact O-N 3.03Å; K176-A180 VanDerWaalsContact O-CB 3.24Å; K176-A180 WeakPolarHBondContact O-CB 3.41Å; K176-A180 PolarHBondContact O-N 3.38Å; K176-E313 IonicContact NZ-OE1 2.99Å; K176-S320 WeakPolarHBondContact CA-OG 3.17Å
177E93.3Very high90.5Very high54 Ų5432.7 Ų32.725%0.25218%0.182SC..Hα-helixtrans-58.4-47.1174.217664.3-144.300110.6E174 M179 A180 R181 R207E174-E177 HydrophobicContact CB-CB 4.48Å; E174-E177 WeakPolarHBondContact OE2-CA 3.32Å; E174-E177 WeakPolarHBondContact OE2-CB 3.23Å; E174-E177 PolarHBondContact OE2-N 2.75Å; E177-M179 PolarHBondContact O-N 3.07Å; E177-A180 PolarHBondContact O-N 3.09Å; E177-R181 VanDerWaalsContact O-CG 3.23Å; E177-R181 WeakPolarHBondContact O-CG 3.24Å; E177-R181 PolarHBondContact O-N 2.89Å; E177-R181 WeakPolarHBondContact OE1-CD 3.47Å; E177-R207 IonicContact OE1-CZ 2.77Å; E177-R207 IonicContact OE1-NE 3.94Å; E177-R207 PolarHBondContact OE1-NE 3.18Å; E177-R207 IonicContact OE1-NH1 3.86Å; E177-R207 PolarHBondContact OE1-NH1 3.42Å; E177-R207 IonicContact OE1-NH2 3.44Å; E177-R207 PolarHBondContact OE1-NH2 2.87Å; E177-R207 VanDerWaalsContact OE1-NH2 3.09Å; E177-R207 IonicContact OE2-CZ 2.78Å; E177-R207 IonicContact OE2-NH1 3.39Å; E177-R207 PolarHBondContact OE2-NH1 2.89Å; E177-R207 IonicContact OE2-NH2 3.66Å; E177-R207 PolarHBondContact OE2-NH2 3.43Å
178L95.3Very high91.7Very high7 Ų729.3 Ų29.34%0.03715%0.154CC..Hα-helixtrans-61.2-46.4-180-175.765.4000111.9F156 I160 L173 E174 I175 K176 R181 F182F156-L178 HydrophobicContact CD2-CD1 4.31Å; F156-L178 HydrophobicContact CE2-CD1 3.68Å; F156-L178 HydrophobicContact CE2-CD2 3.85Å; F156-L178 HydrophobicContact CE2-CG 3.53Å; F156-L178 HydrophobicContact CZ-CD2 4.18Å; F156-L178 HydrophobicContact CZ-CG 4.17Å; I160-L178 HydrophobicContact CD1-CD2 4.2Å; I160-L178 HydrophobicContact CG1-CD1 4.45Å; I160-L178 HydrophobicContact CG1-CD2 3.89Å; L173-L178 HydrophobicContact CD1-CD2 4.19Å; E174-L178 WeakPolarHBondContact O-CB 3.28Å; E174-L178 PolarHBondContact O-N 3.04Å; I175-L178 PolarHBondContact O-N 3.17Å; K176-L178 VanDerWaalsContact C-N 3.33Å; K176-L178 PolarHBondContact O-N 3.46Å; L178-R181 PolarHBondContact O-N 3.07Å; L178-F182 PolarHBondContact O-N 2.91Å
179M96.6Very high93Very high0 Ų020.9 Ų20.90%012%0.116CC..Hα-helixtrans-65.4-38.2175.4-68.1-60.594.400111.9F156 I175 K176 E177 R181 F182 T183 S316 M319 S320 L323 I468F156-M179 HydrophobicContact CE1-CE 3.79Å; F156-M179 HydrophobicContact CE2-CE 3.87Å; F156-M179 HydrophobicContact CZ-CE 3.13Å; I175-M179 HydrophobicContact CG2-CG 3.99Å; I175-M179 WeakPolarHBondContact O-CB 3.22Å; I175-M179 WeakPolarHBondContact O-CG 3.34Å; I175-M179 PolarHBondContact O-N 3.12Å; K176-M179 PolarHBondContact O-N 3.03Å; E177-M179 PolarHBondContact O-N 3.07Å; M179-R181 VanDerWaalsContact C-N 3.33Å; M179-R181 PolarHBondContact O-N 2.74Å; M179-F182 PolarHBondContact O-N 2.9Å; M179-T183 VanDerWaalsContact O-CG2 3.3Å; M179-T183 WeakPolarHBondContact O-CG2 3.37Å; M179-T183 PolarHBondContact O-N 3.29Å; M179-T183 PolarHBondContact O-OG1 2.92Å; M179-S316 VanDerWaalsContact C-CB 3.4Å; M179-S316 WeakPolarHBondContact O-CB 3.29Å; M179-M319 HydrophobicContact CB-CE 4.33Å; M179-M319 HydrophobicContact CG-CB 3.94Å; M179-M319 HydrophobicContact SD-CB 3.45Å; M179-M319 WeakPolarHBondContact SD-CB 3.47Å; M179-M319 HydrophobicContact SD-CE 3.78Å; M179-M319 HydrophobicContact SD-CG 4.22Å; M179-M319 HydrophobicContact SD-SD 3.74Å; M179-S320 WeakPolarHBondContact CG-OG 3.42Å; M179-L323 HydrophobicContact SD-CD1 4.19Å; M179-I468 HydrophobicContact CE-CD1 3.59Å; M179-I468 HydrophobicContact SD-CD1 4.22Å
180A93.6Very high93.5Very high4 Ų415.6 Ų15.63%0.0339%0.088CC..Hα-helixtrans-64.1-38.8176.700000111.6K176 E177 T183 T184 S316K176-A180 VanDerWaalsContact O-CB 3.24Å; K176-A180 WeakPolarHBondContact O-CB 3.41Å; K176-A180 PolarHBondContact O-N 3.38Å; E177-A180 PolarHBondContact O-N 3.09Å; A180-T183 PolarHBondContact O-OG1 2.73Å; A180-T184 VanDerWaalsContact O-CB 3.23Å; A180-T184 WeakPolarHBondContact O-CB 3.49Å; A180-T184 PolarHBondContact O-N 3.49Å; A180-T184 PolarHBondContact O-OG1 3.3Å; A180-S316 VanDerWaalsContact CA-CB 3.49Å
181R94.1Very high93.1Very high20 Ų2014.9 Ų14.98%0.0758%0.08CC..Hα-helixtrans-67.4-47.3175.8-67.2165.573-170.98.3111.5E177 L178 M179 T183 T184 D185 T198 L199E177-R181 VanDerWaalsContact O-CG 3.23Å; E177-R181 WeakPolarHBondContact O-CG 3.24Å; E177-R181 PolarHBondContact O-N 2.89Å; E177-R181 WeakPolarHBondContact OE1-CD 3.47Å; L178-R181 PolarHBondContact O-N 3.07Å; M179-R181 VanDerWaalsContact C-N 3.33Å; M179-R181 PolarHBondContact O-N 2.74Å; R181-T183 PolarHBondContact O-N 3.17Å; R181-T184 PolarHBondContact O-N 3.12Å; R181-D185 PolarHBondContact O-N 3.09Å; R181-T198 WeakPolarHBondContact CA-OG1 3.41Å; R181-T198 PolarHBondContact NE-O 3.46Å; R181-T198 PolarHBondContact NH2-O 3.42Å; R181-T198 PolarHBondContact O-OG1 2.66Å; R181-L199 HydrophobicContact CB-CD2 4.05Å; R181-L199 PolarHBondContact NH2-O 3.48Å
182F96.1Very high92.4Very high0 Ų014.1 Ų14.10%07%0.073CC..Hα-helixtrans-55.4-51.8175.5169.8-116.5000112V152 F156 L178 M179 T184 D185 V186 L199 M319V152-F182 HydrophobicContact CB-CE2 4.49Å; V152-F182 HydrophobicContact CG1-CD2 3.9Å; V152-F182 HydrophobicContact CG1-CE2 3.99Å; F156-F182 HydrophobicContact CB-CD2 3.79Å; F156-F182 HydrophobicContact CB-CE2 4.35Å; F156-F182 AromaticContact CD1-CD2 3.94Å; F156-F182 HydrophobicContact CD1-CD2 3.94Å; F156-F182 HydrophobicContact CD1-CE2 4.33Å; F156-F182 HydrophobicContact CD1-CG 4.11Å; F156-F182 HydrophobicContact CD2-CB 4.17Å; F156-F182 HydrophobicContact CG-CB 4.21Å; F156-F182 AromaticContact CG-CD2 3.83Å; F156-F182 HydrophobicContact CG-CD2 3.83Å; F156-F182 HydrophobicContact CG-CG 4.13Å; L178-F182 PolarHBondContact O-N 2.91Å; M179-F182 PolarHBondContact O-N 2.9Å; F182-T184 VanDerWaalsContact C-N 3.34Å; F182-T184 PolarHBondContact O-N 2.9Å; F182-D185 PolarHBondContact O-N 3.23Å; F182-V186 HydrophobicContact CD2-CG2 4.07Å; F182-V186 HydrophobicContact CE1-CG2 4.32Å; F182-V186 HydrophobicContact CE2-CG2 3.61Å; F182-V186 HydrophobicContact CZ-CG2 3.76Å; F182-V186 WeakPolarHBondContact O-CG2 3.44Å; F182-V186 PolarHBondContact O-N 3.41Å; F182-L199 HydrophobicContact CB-CD2 4.21Å; F182-M319 HydrophobicContact CD1-CE 3.73Å; F182-M319 HydrophobicContact CD1-SD 4.24Å; F182-M319 HydrophobicContact CE1-CE 4.07Å; F182-M319 HydrophobicContact CE1-SD 4.17Å
183T95.3Very high91.7Very high0 Ų011.8 Ų11.80%06%0.062CC..Hα-helixtrans-69.3-30.7-178.355.70000113.1M179 A180 R181 V186 I187 F312 M319 Q460M179-T183 VanDerWaalsContact O-CG2 3.3Å; M179-T183 WeakPolarHBondContact O-CG2 3.37Å; M179-T183 PolarHBondContact O-N 3.29Å; M179-T183 PolarHBondContact O-OG1 2.92Å; A180-T183 PolarHBondContact O-OG1 2.73Å; R181-T183 PolarHBondContact O-N 3.17Å; T183-V186 PolarHBondContact O-N 3.27Å; T183-I187 WeakPolarHBondContact O-CG2 3.49Å; T183-I187 PolarHBondContact O-N 3.22Å; T183-F312 PolarHBondContact OG1-O 3.34Å; T183-F312 VanDerWaalsContact OG1-O 3.08Å; T183-M319 HydrophobicContact CG2-CE 3.26Å; T183-Q460 VanDerWaalsContact CG2-OE1 3.3Å
184T93.9Very high90.9Very high0 Ų013.2 Ų13.20%07%0.07CC..Hα-helixtrans-63-45.3171.8-64.70000111.2A180 R181 F182 I187 G188 T198 F206 Y308A180-T184 VanDerWaalsContact O-CB 3.23Å; A180-T184 WeakPolarHBondContact O-CB 3.49Å; A180-T184 PolarHBondContact O-N 3.49Å; A180-T184 PolarHBondContact O-OG1 3.3Å; R181-T184 PolarHBondContact O-N 3.12Å; F182-T184 VanDerWaalsContact C-N 3.34Å; F182-T184 PolarHBondContact O-N 2.9Å; T184-I187 WeakPolarHBondContact O-CG2 3.46Å; T184-G188 WeakPolarHBondContact O-CA 3.37Å; T184-G188 PolarHBondContact O-N 2.82Å; T184-T198 HydrophobicContact CG2-CG2 3.72Å; T184-F206 HydrophobicContact CG2-CD1 3.93Å; T184-F206 HydrophobicContact CG2-CE1 4.41Å; T184-Y308 HydrophobicContact CG2-CE2 4.25Å
185D93.9Very high90.2Very high9 Ų917.6 Ų17.65%0.0489%0.09CC..Hα-helixtrans-68.8-36.8178.2-741.3000111.6V152 R181 F182 T189 C196 N197 T198 L199V152-D185 HydrophobicContact CG1-CB 3.72Å; R181-D185 PolarHBondContact O-N 3.09Å; F182-D185 PolarHBondContact O-N 3.23Å; D185-T189 VanDerWaalsContact O-CB 3.31Å; D185-T189 WeakPolarHBondContact O-CB 3.31Å; D185-T189 PolarHBondContact O-N 3.37Å; D185-T189 PolarHBondContact O-OG1 3.48Å; D185-C196 WeakPolarHBondContact OD1-CB 3.35Å; D185-N197 PolarHBondContact OD1-N 3Å; D185-T198 VanDerWaalsContact CG-N 3.33Å; D185-T198 VanDerWaalsContact CG-OG1 3.29Å; D185-T198 VanDerWaalsContact OD1-CB 3.31Å; D185-T198 WeakPolarHBondContact OD1-CB 3.41Å; D185-T198 WeakPolarHBondContact OD1-CG2 3.18Å; D185-T198 PolarHBondContact OD1-N 3.07Å; D185-T198 PolarHBondContact OD1-OG1 2.89Å; D185-T198 PolarHBondContact OD2-N 2.77Å; D185-L199 HydrophobicContact CB-CD1 4.48Å; D185-L199 WeakPolarHBondContact OD2-CB 3.24Å; D185-L199 WeakPolarHBondContact OD2-CG 3.22Å; D185-L199 PolarHBondContact OD2-N 3.26Å
186V94.2Very high89.5Confident0 Ų018.3 Ų18.30%010%0.095CC..Hα-helixtrans-61.7-53.9174.2168.90000111V149 V152 F182 T183 T189 C190 F456 Q460V149-V186 HydrophobicContact CG1-CG1 4.27Å; V149-V186 HydrophobicContact CG1-CG2 4.16Å; V149-V186 HydrophobicContact CG2-CG1 4.15Å; V152-V186 HydrophobicContact CB-CG2 4.04Å; V152-V186 HydrophobicContact CG1-CG2 3.75Å; F182-V186 HydrophobicContact CD2-CG2 4.07Å; F182-V186 HydrophobicContact CE1-CG2 4.32Å; F182-V186 HydrophobicContact CE2-CG2 3.61Å; F182-V186 HydrophobicContact CZ-CG2 3.76Å; F182-V186 WeakPolarHBondContact O-CG2 3.44Å; F182-V186 PolarHBondContact O-N 3.41Å; T183-V186 PolarHBondContact O-N 3.27Å; V186-T189 PolarHBondContact O-N 3.31Å; V186-C190 VanDerWaalsContact O-CB 3.24Å; V186-C190 WeakPolarHBondContact O-CB 3.18Å; V186-C190 PolarHBondContact O-N 2.94Å; V186-C190 PolarHBondContact O-SG 2.96Å; V186-F456 HydrophobicContact CG1-CE1 4.36Å; V186-F456 HydrophobicContact CG1-CZ 3.75Å; V186-Q460 HydrophobicContact CG1-CB 4.13Å
187I91.2Very high89.1Confident8 Ų820.2 Ų20.24%0.04111%0.107CC..Hα-helixtrans-68.5-38.3-179-165.567.5000111.5T183 T184 T189 A191 F192 Y308 F312 F456T183-I187 WeakPolarHBondContact O-CG2 3.49Å; T183-I187 PolarHBondContact O-N 3.22Å; T184-I187 WeakPolarHBondContact O-CG2 3.46Å; I187-T189 VanDerWaalsContact C-N 3.34Å; I187-T189 PolarHBondContact O-N 3.34Å; I187-A191 HydrophobicContact CD1-CB 3.69Å; I187-A191 HydrophobicContact CG1-CB 4.05Å; I187-A191 WeakPolarHBondContact O-CA 3.3Å; I187-A191 WeakPolarHBondContact O-CB 3.15Å; I187-A191 PolarHBondContact O-N 2.96Å; I187-F192 HydrophobicContact CG1-CE2 4.08Å; I187-F192 HydrophobicContact CG1-CZ 4.49Å; I187-Y308 HydrophobicContact CG2-CD2 3.7Å; I187-Y308 HydrophobicContact CG2-CE2 4.04Å; I187-F312 HydrophobicContact CG2-CB 4.34Å; I187-F456 HydrophobicContact CD1-CE1 3.73Å; I187-F456 HydrophobicContact CD1-CZ 4.08Å
188G89.8Confident88.9Confident0 Ų017.7 Ų17.70%010%0.095CC..Iπ-helixtrans-52.6-52.1173.800000111.8T184 F192 G193 I194T184-G188 WeakPolarHBondContact O-CA 3.37Å; T184-G188 PolarHBondContact O-N 2.82Å; G188-F192 CarbonylContact O-C 3.59Å; G188-F192 WeakPolarHBondContact O-CA 3.47Å; G188-F192 WeakPolarHBondContact O-CB 3.4Å; G188-F192 PolarHBondContact O-N 3.28Å; G188-F192 VanDerWaalsContact O-N 3.15Å; G188-G193 PolarHBondContact O-N 2.69Å; G188-I194 CarbonylContact C-O 3.4Å; G188-I194 PolarHBondContact O-N 3.31Å
189T88.6Confident88.6Confident16 Ų1617.4 Ų17.410%0.0989%0.094CC..Iπ-helixtrans-76.4-45.6-175.4-47.10000112.4T148 D185 V186 I187 G193 I194 R268T148-T189 HydrophobicContact CG2-CG2 3.36Å; D185-T189 VanDerWaalsContact O-CB 3.31Å; D185-T189 WeakPolarHBondContact O-CB 3.31Å; D185-T189 PolarHBondContact O-N 3.37Å; D185-T189 PolarHBondContact O-OG1 3.48Å; V186-T189 PolarHBondContact O-N 3.31Å; I187-T189 VanDerWaalsContact C-N 3.34Å; I187-T189 PolarHBondContact O-N 3.34Å; T189-G193 WeakPolarHBondContact O-CA 3.29Å; T189-G193 PolarHBondContact O-N 3.46Å; T189-I194 PolarHBondContact N-O 3.39Å; T189-R268 VanDerWaalsContact CG2-NH2 3.26Å
190C86.3Confident88.3Confident6 Ų622.5 Ų22.54%0.04111%0.113CC..Iπ-helixtrans-75.7-41.4-175.8-70.10000113M145 T148 V186 D270 F456M145-C190 HydrophobicContact SD-CB 4.05Å; T148-C190 VanDerWaalsContact CG2-SG 3.56Å; V186-C190 VanDerWaalsContact O-CB 3.24Å; V186-C190 WeakPolarHBondContact O-CB 3.18Å; V186-C190 PolarHBondContact O-N 2.94Å; V186-C190 PolarHBondContact O-SG 2.96Å; C190-D270 WeakPolarHBondContact O-CB 3.31Å; C190-F456 HydrophobicContact CB-CE2 4.03Å; C190-F456 HydrophobicContact CB-CZ 4.1Å
191A80.8Confident87.9Confident6 Ų625.8 Ų25.85%0.0513%0.133CC..Iπ-helixtrans-88.2-43.6-176.100000112I187 F271 M272I187-A191 HydrophobicContact CD1-CB 3.69Å; I187-A191 HydrophobicContact CG1-CB 4.05Å; I187-A191 WeakPolarHBondContact O-CA 3.3Å; I187-A191 WeakPolarHBondContact O-CB 3.15Å; I187-A191 PolarHBondContact O-N 2.96Å; A191-F271 HydrophobicContact CB-CB 4Å; A191-F271 HydrophobicContact CB-CD1 4.29Å; A191-F271 CarbonylContact O-C 3.53Å; A191-F271 WeakPolarHBondContact O-CA 3.49Å; A191-F271 VanDerWaalsContact O-CB 3.28Å; A191-F271 WeakPolarHBondContact O-CB 3.37Å; A191-F271 PolarHBondContact O-N 2.91Å; A191-F271 VanDerWaalsContact O-N 3.14Å; A191-M272 PolarHBondContact O-N 3.28Å
192F79.6Confident87Confident1 Ų127.5 Ų27.50%0.00415%0.147CC..Iπ-helixtrans-108.3-11.9-169.5-47.1-54.5000113.5I187 G188 I194 F206 R261 F271 M272 V304 Y308I187-F192 HydrophobicContact CG1-CE2 4.08Å; I187-F192 HydrophobicContact CG1-CZ 4.49Å; G188-F192 CarbonylContact O-C 3.59Å; G188-F192 WeakPolarHBondContact O-CA 3.47Å; G188-F192 WeakPolarHBondContact O-CB 3.4Å; G188-F192 PolarHBondContact O-N 3.28Å; G188-F192 VanDerWaalsContact O-N 3.15Å; F192-I194 HydrophobicContact CB-CB 4.39Å; F192-I194 HydrophobicContact CB-CD1 3.67Å; F192-I194 HydrophobicContact CB-CG1 3.86Å; F192-I194 PolarHBondContact O-N 3.21Å; F192-F206 HydrophobicContact CD2-CE1 4.46Å; F192-F206 HydrophobicContact CD2-CE2 4.5Å; F192-F206 AromaticContact CD2-CZ 3.67Å; F192-F206 HydrophobicContact CD2-CZ 3.67Å; F192-F206 AromaticContact CE2-CZ 3.8Å; F192-F206 HydrophobicContact CE2-CZ 3.8Å; F192-R261 PolarHBondContact O-NH2 3.04Å; F192-F271 HydrophobicContact CE1-CD1 4.36Å; F192-M272 HydrophobicContact CD1-CE 4.34Å; F192-V304 HydrophobicContact CD1-CG1 3.91Å; F192-V304 HydrophobicContact CD1-CG2 4.38Å; F192-V304 HydrophobicContact CE1-CB 4.04Å; F192-V304 HydrophobicContact CE1-CG1 3.55Å; F192-V304 HydrophobicContact CE1-CG2 4.1Å; F192-V304 HydrophobicContact CZ-CG1 4.12Å; F192-V304 WeakPolarHBondContact CZ-O 3.47Å; F192-Y308 HydrophobicContact CE2-CD2 4.17Å; F192-Y308 HydrophobicContact CE2-CG 4.33Å
193G79.3Confident85.9Confident16 Ų1633.2 Ų33.217%0.16518%0.182CC..  trans66.627.7-174.100000112.6G188 T189 R268 D270G188-G193 PolarHBondContact O-N 2.69Å; T189-G193 WeakPolarHBondContact O-CA 3.29Å; T189-G193 PolarHBondContact O-N 3.46Å; G193-R268 VanDerWaalsContact C-NH1 3.3Å; G193-R268 PolarHBondContact O-NH1 3.29Å; G193-D270 WeakPolarHBondContact CA-OD2 3.28Å; G193-D270 PolarHBondContact N-OD2 3.01Å
194I80.8Confident85.1Confident45 Ų4534.2 Ų34.223%0.23119%0.189CC..  trans-108126.6-178.5-60.3170.6000108.2G188 T189 F192 C196 L253G188-I194 CarbonylContact C-O 3.4Å; G188-I194 PolarHBondContact O-N 3.31Å; T189-I194 PolarHBondContact N-O 3.39Å; F192-I194 HydrophobicContact CB-CB 4.39Å; F192-I194 HydrophobicContact CB-CD1 3.67Å; F192-I194 HydrophobicContact CB-CG1 3.86Å; F192-I194 PolarHBondContact O-N 3.21Å; I194-C196 PolarHBondContact O-N 3.29Å; I194-L253 HydrophobicContact CD1-CD1 3.71Å; I194-L253 HydrophobicContact CD1-CD2 4.31Å; I194-L253 HydrophobicContact CD1-CG 4.35Å
195E81.8Confident84.5Confident137 Ų13739.7 Ų39.764%0.6422%0.218SC*.  trans-83.593.5170.9-63.5-170.4170.500108.8N197E195-N197 VanDerWaalsContact C-N 3.28Å; E195-N197 PolarHBondContact O-N 2.98Å
196C81.6Confident83.9Confident19 Ų1939.9 Ų39.913%0.12822%0.218CC..  trans-72.7-24.1-179.1-55.60000112.8D185 I194 T198 F206D185-C196 WeakPolarHBondContact OD1-CB 3.35Å; I194-C196 PolarHBondContact O-N 3.29Å; C196-T198 HydrophobicContact CB-CG2 3.75Å; C196-T198 PolarHBondContact O-N 2.91Å; C196-F206 VanDerWaalsContact SG-CD1 3.5Å
197N86.1Confident83.4Confident77 Ų7740.9 Ų40.941%0.41222%0.222SC..  trans46.335.4-178.4-165.125000113.4D185 E195 L199 R200 T201D185-N197 PolarHBondContact OD1-N 3Å; E195-N197 VanDerWaalsContact C-N 3.28Å; E195-N197 PolarHBondContact O-N 2.98Å; N197-L199 PolarHBondContact O-N 3.06Å; N197-R200 PolarHBondContact O-N 3.2Å; N197-T201 PolarHBondContact O-N 3.26Å
198T88.8Confident83.2Confident0 Ų042.8 Ų42.80%023%0.234CC..THydrogen-bonded Turntrans-68.8-26.3-176.466.20000111.2R181 T184 D185 C196 R200 T201 S204 R207R181-T198 WeakPolarHBondContact CA-OG1 3.41Å; R181-T198 PolarHBondContact NE-O 3.46Å; R181-T198 PolarHBondContact NH2-O 3.42Å; R181-T198 PolarHBondContact O-OG1 2.66Å; T184-T198 HydrophobicContact CG2-CG2 3.72Å; D185-T198 VanDerWaalsContact CG-N 3.33Å; D185-T198 VanDerWaalsContact CG-OG1 3.29Å; D185-T198 VanDerWaalsContact OD1-CB 3.31Å; D185-T198 WeakPolarHBondContact OD1-CB 3.41Å; D185-T198 WeakPolarHBondContact OD1-CG2 3.18Å; D185-T198 PolarHBondContact OD1-N 3.07Å; D185-T198 PolarHBondContact OD1-OG1 2.89Å; D185-T198 PolarHBondContact OD2-N 2.77Å; C196-T198 HydrophobicContact CB-CG2 3.75Å; C196-T198 PolarHBondContact O-N 2.91Å; T198-R200 VanDerWaalsContact C-N 3.25Å; T198-R200 PolarHBondContact O-N 3.42Å; T198-T201 WeakPolarHBondContact CA-O 3.44Å; T198-T201 CarbonylContact O-C 3.58Å; T198-T201 PolarHBondContact O-N 3.22Å; T198-S204 VanDerWaalsContact CG2-OG 3.32Å; T198-S204 WeakPolarHBondContact CG2-OG 3.42Å; T198-R207 HydrophobicContact CG2-CB 4.48Å
199L89.1Confident83.2Confident2 Ų244.1 Ų44.11%0.0124%0.241CC..THydrogen-bonded Turntrans-60.5-25.4173.8-75.9172000114.8V152 F156 V159 R181 F182 D185 N197V152-L199 HydrophobicContact CG1-CD1 4.03Å; F156-L199 HydrophobicContact CB-CD1 3.89Å; F156-L199 HydrophobicContact CB-CD2 4.33Å; F156-L199 HydrophobicContact CD2-CD2 3.71Å; F156-L199 HydrophobicContact CG-CD2 4.42Å; V159-L199 WeakPolarHBondContact CG1-O 3.17Å; V159-L199 HydrophobicContact CG2-CB 4.34Å; R181-L199 HydrophobicContact CB-CD2 4.05Å; R181-L199 PolarHBondContact NH2-O 3.48Å; F182-L199 HydrophobicContact CB-CD2 4.21Å; D185-L199 HydrophobicContact CB-CD1 4.48Å; D185-L199 WeakPolarHBondContact OD2-CB 3.24Å; D185-L199 WeakPolarHBondContact OD2-CG 3.22Å; D185-L199 PolarHBondContact OD2-N 3.26Å; N197-L199 PolarHBondContact O-N 3.06Å
200R88.9Confident83.1Confident106 Ų10643.4 Ų43.440%0.424%0.236SC..THydrogen-bonded Turntrans-106.9-31.3172.4-66.6-165.3172.4-81.7-4.6113.2E155 V159 E162 N197 T198 P202E155-R200 IonicContact OE1-CZ 3.77Å; E155-R200 IonicContact OE1-NE 3.33Å; E155-R200 PolarHBondContact OE1-NE 3.34Å; E155-R200 IonicContact OE1-NH2 3.53Å; E155-R200 PolarHBondContact OE1-NH2 2.97Å; V159-R200 HydrophobicContact CG2-CG 4.1Å; E162-R200 IonicContact OE1-CZ 2.8Å; E162-R200 IonicContact OE1-NH1 3.3Å; E162-R200 PolarHBondContact OE1-NH1 2.85Å; E162-R200 IonicContact OE1-NH2 3.23Å; E162-R200 PolarHBondContact OE1-NH2 2.75Å; E162-R200 IonicContact OE2-CZ 3.27Å; E162-R200 IonicContact OE2-NH1 2.83Å; E162-R200 PolarHBondContact OE2-NH1 3.48Å; E162-R200 IonicContact OE2-NH2 2.78Å; N197-R200 PolarHBondContact O-N 3.2Å; T198-R200 VanDerWaalsContact C-N 3.25Å; T198-R200 PolarHBondContact O-N 3.42Å; R200-P202 WeakPolarHBondContact O-CD 3.46Å
201T85.7Confident83Confident74 Ų7446.5 Ų46.545%0.45425%0.25SC..  trans-116.589.3179.7-50.50000109.5N197 T198 V203N197-T201 PolarHBondContact O-N 3.26Å; T198-T201 WeakPolarHBondContact CA-O 3.44Å; T198-T201 CarbonylContact O-C 3.58Å; T198-T201 PolarHBondContact O-N 3.22Å; T201-V203 PolarHBondContact O-N 3.03Å; T201-V203 VanDerWaalsContact O-N 3.12Å
202P75.1Confident83.4Confident56 Ų5648.8 Ų48.836%0.36426%0.259SS..SBendtrans-59.4-29.3-171.1-14.820.6000114.1R200R200-P202 WeakPolarHBondContact O-CD 3.46Å
203V74.3Confident83.7Confident120 Ų12049.9 Ų49.973%0.72727%0.265SS*.  trans-96.5104178.9-174.40000108.7T201T201-V203 PolarHBondContact O-N 3.03Å; T201-V203 VanDerWaalsContact O-N 3.12Å
204S78.3Confident83.8Confident21 Ų2150.6 Ų50.615%0.14726%0.264CS..  trans-126149.3167.974.50000110T198 F206 R207 T208T198-S204 VanDerWaalsContact CG2-OG 3.32Å; T198-S204 WeakPolarHBondContact CG2-OG 3.42Å; S204-F206 PolarHBondContact O-N 3.47Å; S204-R207 PolarHBondContact O-N 3.09Å; S204-R207 WeakPolarHBondContact OG-CB 3.28Å; S204-R207 PolarHBondContact OG-N 3.48Å; S204-R207 VanDerWaalsContact OG-N 3.13Å; S204-T208 WeakPolarHBondContact O-CB 3.38Å; S204-T208 PolarHBondContact O-N 2.91Å; S204-T208 PolarHBondContact O-OG1 3.49Å
205D80.6Confident83.8Confident114 Ų11453.3 Ų53.361%0.6128%0.283SS*.Hα-helixtrans-56.7-40174.2-71.9-16.1000110.5R207 T208 M209 F249D205-R207 PolarHBondContact O-N 3.07Å; D205-T208 PolarHBondContact O-N 3.44Å; D205-M209 WeakPolarHBondContact O-CB 3.45Å; D205-M209 WeakPolarHBondContact O-CG 3.29Å; D205-M209 PolarHBondContact O-N 2.99Å; D205-F249 HydrophobicContact CB-CE2 3.82Å; D205-F249 HydrophobicContact CB-CZ 4.38Å
206F80.6Confident83.9Confident14 Ų1450.4 Ų50.46%0.06127%0.272CS..Hα-helixtrans-56.7-50.1178.8-160.1-110.8000111.5T184 F192 C196 S204 G210 F249 F250 L253 Y308T184-F206 HydrophobicContact CG2-CD1 3.93Å; T184-F206 HydrophobicContact CG2-CE1 4.41Å; F192-F206 HydrophobicContact CD2-CE1 4.46Å; F192-F206 HydrophobicContact CD2-CE2 4.5Å; F192-F206 AromaticContact CD2-CZ 3.67Å; F192-F206 HydrophobicContact CD2-CZ 3.67Å; F192-F206 AromaticContact CE2-CZ 3.8Å; F192-F206 HydrophobicContact CE2-CZ 3.8Å; C196-F206 VanDerWaalsContact SG-CD1 3.5Å; S204-F206 PolarHBondContact O-N 3.47Å; F206-G210 PolarHBondContact O-N 3.01Å; F206-G210 VanDerWaalsContact O-N 3.08Å; F206-F249 HydrophobicContact CB-CZ 4.24Å; F206-F249 AromaticContact CD2-CE1 3.75Å; F206-F249 HydrophobicContact CD2-CE1 3.75Å; F206-F249 AromaticContact CD2-CZ 3.79Å; F206-F249 HydrophobicContact CD2-CZ 3.79Å; F206-F249 HydrophobicContact CE2-CE1 4.38Å; F206-F249 HydrophobicContact CG-CZ 4.49Å; F206-F250 HydrophobicContact CE2-CE1 4.37Å; F206-L253 HydrophobicContact CD2-CD2 4.13Å; F206-L253 HydrophobicContact CE2-CD2 3.59Å; F206-Y308 HydrophobicContact CD1-CD2 4.16Å; F206-Y308 AromaticContact CD1-CE2 3.49Å; F206-Y308 HydrophobicContact CD1-CE2 3.49Å; F206-Y308 VanDerWaalsContact CD1-CE2 3.49Å; F206-Y308 AromaticContact CD1-CZ 3.69Å; F206-Y308 AromaticContact CE1-CD2 3.23Å; F206-Y308 HydrophobicContact CE1-CD2 3.23Å; F206-Y308 HydrophobicContact CE1-CE1 4.36Å; F206-Y308 AromaticContact CE1-CE2 2.99Å; F206-Y308 HydrophobicContact CE1-CE2 2.99Å; F206-Y308 HydrophobicContact CE1-CG 4.07Å; F206-Y308 AromaticContact CE1-CZ 3.62Å; F206-Y308 HydrophobicContact CE2-CD2 4.46Å; F206-Y308 HydrophobicContact CG-CE2 4.49Å; F206-Y308 HydrophobicContact CZ-CD1 4.36Å; F206-Y308 AromaticContact CZ-CD2 3.39Å; F206-Y308 HydrophobicContact CZ-CD2 3.39Å; F206-Y308 HydrophobicContact CZ-CE1 4.46Å; F206-Y308 AromaticContact CZ-CE2 3.63Å; F206-Y308 HydrophobicContact CZ-CE2 3.63Å; F206-Y308 AromaticContact CZ-CG 3.81Å; F206-Y308 HydrophobicContact CZ-CG 3.81Å; F206-Y308 PolarHBondContact O-OH 3Å
207R84.1Confident84.1Confident20 Ų2052 Ų528%0.07528%0.278CS..Hα-helixtrans-67-45178.7-173.9169.9-169.5-88.9-9.5112.9E177 T198 S204 D205 M209 G210 Q211 Y308E177-R207 IonicContact OE1-CZ 2.77Å; E177-R207 IonicContact OE1-NE 3.94Å; E177-R207 PolarHBondContact OE1-NE 3.18Å; E177-R207 IonicContact OE1-NH1 3.86Å; E177-R207 PolarHBondContact OE1-NH1 3.42Å; E177-R207 IonicContact OE1-NH2 3.44Å; E177-R207 PolarHBondContact OE1-NH2 2.87Å; E177-R207 VanDerWaalsContact OE1-NH2 3.09Å; E177-R207 IonicContact OE2-CZ 2.78Å; E177-R207 IonicContact OE2-NH1 3.39Å; E177-R207 PolarHBondContact OE2-NH1 2.89Å; E177-R207 IonicContact OE2-NH2 3.66Å; E177-R207 PolarHBondContact OE2-NH2 3.43Å; T198-R207 HydrophobicContact CG2-CB 4.48Å; S204-R207 PolarHBondContact O-N 3.09Å; S204-R207 WeakPolarHBondContact OG-CB 3.28Å; S204-R207 PolarHBondContact OG-N 3.48Å; S204-R207 VanDerWaalsContact OG-N 3.13Å; D205-R207 PolarHBondContact O-N 3.07Å; R207-M209 VanDerWaalsContact C-N 3.32Å; R207-M209 PolarHBondContact O-N 3.04Å; R207-G210 PolarHBondContact O-N 3.3Å; R207-Q211 WeakPolarHBondContact O-CG 3.16Å; R207-Q211 PolarHBondContact O-N 3.37Å; R207-Y308 WeakPolarHBondContact CA-OH 3.42Å
208T87.9Confident84.2Confident49 Ų4952.2 Ų52.230%0.30127%0.273SS..Hα-helixtrans-60.3-44.8-179.6-55.20000110.8S204 D205 G210 Q211 K212S204-T208 WeakPolarHBondContact O-CB 3.38Å; S204-T208 PolarHBondContact O-N 2.91Å; S204-T208 PolarHBondContact O-OG1 3.49Å; D205-T208 PolarHBondContact O-N 3.44Å; T208-G210 VanDerWaalsContact C-N 3.35Å; T208-Q211 PolarHBondContact O-N 2.87Å; T208-K212 WeakPolarHBondContact O-CG 3.07Å; T208-K212 PolarHBondContact O-N 3.35Å; T208-K212 VanDerWaalsContact O-N 3.16Å
209M89.5Confident84.2Confident28 Ų2855.2 Ų55.214%0.13829%0.287CS..Hα-helixtrans-67.9-34.7177.6-63.7-60.1148.500112D205 R207 K212 D245 V246 F249 F250D205-M209 WeakPolarHBondContact O-CB 3.45Å; D205-M209 WeakPolarHBondContact O-CG 3.29Å; D205-M209 PolarHBondContact O-N 2.99Å; R207-M209 VanDerWaalsContact C-N 3.32Å; R207-M209 PolarHBondContact O-N 3.04Å; M209-K212 HydrophobicContact SD-CD 4.26Å; M209-D245 HydrophobicContact SD-CB 4.5Å; M209-V246 HydrophobicContact SD-CG2 4.3Å; M209-F249 HydrophobicContact CB-CD1 3.75Å; M209-F249 HydrophobicContact CB-CE1 4.11Å; M209-F249 HydrophobicContact CB-CG 4.09Å; M209-F249 HydrophobicContact CG-CB 3.94Å; M209-F249 HydrophobicContact CG-CD1 3.81Å; M209-F249 HydrophobicContact CG-CD2 3.94Å; M209-F249 HydrophobicContact CG-CE1 4.29Å; M209-F249 HydrophobicContact CG-CE2 4.41Å; M209-F249 HydrophobicContact CG-CG 3.62Å; M209-F249 HydrophobicContact SD-CB 4.35Å; M209-F250 HydrophobicContact CB-CE2 4.32Å
210G85.6Confident84.2Confident0 Ų056.6 Ų56.60%030%0.302CS..Hα-helixtrans-61.2-44.2172.100000113.7F206 R207 T208 V213 Y308F206-G210 PolarHBondContact O-N 3.01Å; F206-G210 VanDerWaalsContact O-N 3.08Å; R207-G210 PolarHBondContact O-N 3.3Å; T208-G210 VanDerWaalsContact C-N 3.35Å; G210-V213 WeakPolarHBondContact O-CB 3.37Å; G210-V213 PolarHBondContact O-N 3.15Å; G210-Y308 VanDerWaalsContact CA-CE1 3.43Å
211Q84.9Confident84Confident71 Ų7156.8 Ų56.833%0.33231%0.306SS..Hα-helixtrans-67.5-36.2179.4-72.4178.8-29.700113.1R207 T208 V213 F214 T215R207-Q211 WeakPolarHBondContact O-CG 3.16Å; R207-Q211 PolarHBondContact O-N 3.37Å; T208-Q211 PolarHBondContact O-N 2.87Å; Q211-V213 PolarHBondContact O-N 3.28Å; Q211-F214 PolarHBondContact O-N 3.07Å; Q211-F214 VanDerWaalsContact O-N 3.09Å; Q211-T215 PolarHBondContact O-N 2.95Å; Q211-T215 PolarHBondContact O-OG1 3.22Å
212K88.4Confident84Confident55 Ų5559.3 Ų59.324%0.23932%0.315CS..Hα-helixtrans-59.1-29.3177.6-78.3-176.8165.3-1780113.3T208 M209 F214 T215 D216 D245 V246T208-K212 WeakPolarHBondContact O-CG 3.07Å; T208-K212 PolarHBondContact O-N 3.35Å; T208-K212 VanDerWaalsContact O-N 3.16Å; M209-K212 HydrophobicContact SD-CD 4.26Å; K212-F214 PolarHBondContact O-N 2.97Å; K212-T215 WeakPolarHBondContact CA-OG1 3.38Å; K212-T215 PolarHBondContact O-N 3.45Å; K212-D216 WeakPolarHBondContact CG-OD2 2.93Å; K212-D216 WeakPolarHBondContact O-CB 3.44Å; K212-D216 PolarHBondContact O-N 3.07Å; K212-D245 IonicContact NZ-OD2 2.69Å; K212-D245 PolarHBondContact NZ-OD2 3.18Å; K212-V246 HydrophobicContact CB-CG2 3.73Å; K212-V246 HydrophobicContact CD-CG2 4.42Å
213V85.6Confident84.7Confident23 Ų2360.5 Ų60.514%0.13932%0.319CS..Hα-helixtrans-57.9-33176.2-179.80000112.4G210 Q211 V246 F305 V309G210-V213 WeakPolarHBondContact O-CB 3.37Å; G210-V213 PolarHBondContact O-N 3.15Å; Q211-V213 PolarHBondContact O-N 3.28Å; V213-V246 HydrophobicContact CG2-CG1 3.95Å; V213-F305 HydrophobicContact CG1-CE2 4.37Å; V213-F305 HydrophobicContact CG1-CZ 3.82Å; V213-F305 HydrophobicContact CG2-CE2 3.52Å; V213-F305 HydrophobicContact CG2-CZ 3.82Å; V213-V309 HydrophobicContact CB-CG2 4.4Å; V213-V309 HydrophobicContact CG1-CG1 4.11Å; V213-V309 HydrophobicContact CG1-CG2 4.2Å; V213-V309 HydrophobicContact CG2-CG2 4Å
214F81.4Confident85.3Confident32 Ų3255.2 Ų55.214%0.1429%0.286CS..Hα-helixtrans-95.7-20.7-176.3-63.6-77.6000113.7Q211 K212 V309 F312 E313Q211-F214 PolarHBondContact O-N 3.07Å; Q211-F214 VanDerWaalsContact O-N 3.09Å; K212-F214 PolarHBondContact O-N 2.97Å; F214-V309 HydrophobicContact CE1-CG1 4.18Å; F214-V309 HydrophobicContact CE2-CG1 3.67Å; F214-V309 HydrophobicContact CZ-CG1 3.31Å; F214-F312 HydrophobicContact CD2-CZ 4.33Å; F214-F312 HydrophobicContact CE2-CE1 4.31Å; F214-F312 HydrophobicContact CE2-CE2 4.49Å; F214-F312 AromaticContact CE2-CZ 3.76Å; F214-F312 HydrophobicContact CE2-CZ 3.76Å; F214-E313 HydrophobicContact CD2-CG 4.35Å; F214-E313 HydrophobicContact CE1-CG 4.24Å; F214-E313 HydrophobicContact CE2-CB 3.67Å; F214-E313 HydrophobicContact CE2-CG 3.82Å; F214-E313 HydrophobicContact CZ-CB 3.63Å; F214-E313 HydrophobicContact CZ-CG 3.74Å
215T80.9Confident85.7Confident101 Ų10155.6 Ų55.662%0.6229%0.286SS*.Hα-helixtrans-107.3-37.8-170.347.70000112.8Q211 K212Q211-T215 PolarHBondContact O-N 2.95Å; Q211-T215 PolarHBondContact O-OG1 3.22Å; K212-T215 WeakPolarHBondContact CA-OG1 3.38Å; K212-T215 PolarHBondContact O-N 3.45Å
216D85.1Confident86Confident76 Ų7652.8 Ų52.841%0.40627%0.269SS..  trans-94.9141.2-173.1-69.9-9.3000112.4K212 P243K212-D216 WeakPolarHBondContact CG-OD2 2.93Å; K212-D216 WeakPolarHBondContact O-CB 3.44Å; K212-D216 PolarHBondContact O-N 3.07Å; D216-P243 HydrophobicContact CB-CG 4.04Å
217M85.1Confident86.5Confident52 Ų5252.2 Ų52.226%0.25627%0.266SS..  trans-119.6112.7172.4-67.5-176.5179.800109.9R47 H219 G220 K221 T224R47-M217 VanDerWaalsContact CD-CE 3.49Å; M217-H219 PolarHBondContact O-N 3.12Å; M217-G220 PolarHBondContact O-N 2.89Å; M217-G220 VanDerWaalsContact O-N 3.11Å; M217-K221 HydrophobicContact CE-CG 4.31Å; M217-K221 HydrophobicContact SD-CB 4.3Å; M217-K221 HydrophobicContact SD-CG 3.82Å; M217-T224 HydrophobicContact CE-CG2 4.45Å; M217-T224 HydrophobicContact SD-CG2 4.27Å
218R88.8Confident86.5Confident82 Ų8254.4 Ų54.431%0.30928%0.276SS..THydrogen-bonded Turntrans-48.8-41.5-178.4-168.9-165.8-177.794.72.9113.6R240 M242 E244R218-R240 WeakPolarHBondContact CD-O 3.34Å; R218-M242 VanDerWaalsContact CD-O 3.32Å; R218-M242 WeakPolarHBondContact CD-O 3.47Å; R218-M242 PolarHBondContact NH1-O 3.16Å; R218-E244 IonicContact CZ-OE2 3.44Å; R218-E244 VanDerWaalsContact CZ-OE2 3.27Å; R218-E244 IonicContact NH1-OE2 3.34Å; R218-E244 PolarHBondContact NH1-OE2 2.75Å; R218-E244 IonicContact NH2-OE2 3.54Å; R218-E244 PolarHBondContact NH2-OE2 2.85Å
219H89.3Confident86.4Confident63 Ų6352.5 Ų52.529%0.29227%0.265SS..THydrogen-bonded Turntrans-112.19.7-173.8-61.7-51.5000113.6M217 L223 R240M217-H219 PolarHBondContact O-N 3.12Å; H219-L223 HydrophobicContact CB-CB 3.53Å; H219-L223 HydrophobicContact CB-CD1 3.83Å; H219-L223 HydrophobicContact CB-CG 4.33Å; H219-R240 PolarHBondContact CD2-O 3.47Å; H219-R240 PolarHBondContact NE2-O 3.05Å
220G88.4Confident86.3Confident32 Ų3255.7 Ų55.733%0.3328%0.279SS..Hα-helixtrans66.8177.1-172.200000114.1M217 L222 T224M217-G220 PolarHBondContact O-N 2.89Å; M217-G220 VanDerWaalsContact O-N 3.11Å; G220-L222 PolarHBondContact O-N 3.43Å; G220-T224 WeakPolarHBondContact O-CB 3.46Å; G220-T224 PolarHBondContact O-N 2.86Å; G220-T224 VanDerWaalsContact O-N 3.12Å; G220-T224 PolarHBondContact O-OG1 3.44Å; G220-T224 VanDerWaalsContact O-OG1 3.07Å
221K84.1Confident86.5Confident110 Ų11057 Ų5748%0.47829%0.287SS..Hα-helixtrans-59.4-46.2-167.8-62.6-175.4-177.4-173.30113.9R47 M217 T224 M225R47-K221 PolarHBondContact O-NZ 3.24Å; M217-K221 HydrophobicContact CE-CG 4.31Å; M217-K221 HydrophobicContact SD-CB 4.3Å; M217-K221 HydrophobicContact SD-CG 3.82Å; K221-T224 PolarHBondContact O-N 2.88Å; K221-M225 HydrophobicContact CB-CE 4.43Å; K221-M225 VanDerWaalsContact O-CG 3.29Å; K221-M225 WeakPolarHBondContact O-CG 3.35Å; K221-M225 PolarHBondContact O-N 3.42Å
222L85.9Confident86.6Confident126 Ų12660.7 Ų60.766%0.6630%0.302SS*.Hα-helixtrans-64.2-49.6-173-68.4174.8000112.5G220 M225 F226G220-L222 PolarHBondContact O-N 3.43Å; L222-M225 HydrophobicContact CD2-CE 3.76Å; L222-M225 PolarHBondContact O-N 3.45Å; L222-F226 PolarHBondContact O-N 3.17Å
223L89.3Confident86.7Confident82 Ų8261.7 Ų61.743%0.42931%0.309SS..Hα-helixtrans-71.1-33.1179.6-72.3176.7000111.8H219 F226 M227 M239H219-L223 HydrophobicContact CB-CB 3.53Å; H219-L223 HydrophobicContact CB-CD1 3.83Å; H219-L223 HydrophobicContact CB-CG 4.33Å; L223-F226 WeakPolarHBondContact O-CB 3.46Å; L223-F226 PolarHBondContact O-N 3.05Å; L223-M227 WeakPolarHBondContact O-CG 3.2Å; L223-M227 PolarHBondContact O-N 2.78Å; L223-M239 HydrophobicContact CB-CE 4.13Å; L223-M239 HydrophobicContact CD2-CE 4.27Å
224T87.7Confident87Confident8 Ų860.6 Ų60.65%0.04930%0.303CS..Hα-helixtrans-62.2-43.4170.7-66.90000112M217 G220 K221 F226 M227 F228 M241M217-T224 HydrophobicContact CE-CG2 4.45Å; M217-T224 HydrophobicContact SD-CG2 4.27Å; G220-T224 WeakPolarHBondContact O-CB 3.46Å; G220-T224 PolarHBondContact O-N 2.86Å; G220-T224 VanDerWaalsContact O-N 3.12Å; G220-T224 PolarHBondContact O-OG1 3.44Å; G220-T224 VanDerWaalsContact O-OG1 3.07Å; K221-T224 PolarHBondContact O-N 2.88Å; T224-F226 VanDerWaalsContact C-N 3.31Å; T224-F226 PolarHBondContact O-N 3.5Å; T224-M227 PolarHBondContact O-N 2.98Å; T224-F228 HydrophobicContact CG2-CD2 3.86Å; T224-F228 HydrophobicContact CG2-CE2 3.39Å; T224-F228 HydrophobicContact CG2-CZ 4.35Å; T224-F228 WeakPolarHBondContact O-CD2 3.29Å; T224-F228 PolarHBondContact O-N 2.8Å; T224-M241 HydrophobicContact CG2-SD 4.42Å
225M85.8Confident87.3Confident29 Ų2961.1 Ų61.114%0.14331%0.31CS..Hα-helixtrans-60.7-39.9173.7-72.6-174.7-69.700111.8Y40 L76 K221 L222 S229Y40-M225 HydrophobicContact CE1-SD 4.37Å; L76-M225 HydrophobicContact CD1-CB 3.95Å; L76-M225 HydrophobicContact CD1-CG 3.96Å; L76-M225 HydrophobicContact CD2-SD 4.18Å; K221-M225 HydrophobicContact CB-CE 4.43Å; K221-M225 VanDerWaalsContact O-CG 3.29Å; K221-M225 WeakPolarHBondContact O-CG 3.35Å; K221-M225 PolarHBondContact O-N 3.42Å; L222-M225 HydrophobicContact CD2-CE 3.76Å; L222-M225 PolarHBondContact O-N 3.45Å; M225-S229 WeakPolarHBondContact O-CB 3.3Å; M225-S229 PolarHBondContact O-N 3.29Å; M225-S229 PolarHBondContact O-OG 3.3Å
226F88.5Confident87.8Confident56 Ų5665.8 Ų65.825%0.24632%0.316CS..Hα-helixtrans-61.2-40.9173.9172.1-95.4000112.9L222 L223 T224 S229 F230 L233 A234 L237 M239L222-F226 PolarHBondContact O-N 3.17Å; L223-F226 WeakPolarHBondContact O-CB 3.46Å; L223-F226 PolarHBondContact O-N 3.05Å; T224-F226 VanDerWaalsContact C-N 3.31Å; T224-F226 PolarHBondContact O-N 3.5Å; F226-S229 WeakPolarHBondContact O-CB 3.31Å; F226-S229 PolarHBondContact O-N 3.15Å; F226-F230 AromaticContact CD2-CD2 3.61Å; F226-F230 HydrophobicContact CD2-CD2 3.61Å; F226-F230 HydrophobicContact CD2-CE2 4.21Å; F226-F230 HydrophobicContact CE2-CB 4.35Å; F226-F230 AromaticContact CE2-CD2 3.67Å; F226-F230 HydrophobicContact CE2-CD2 3.67Å; F226-F230 HydrophobicContact CE2-CE2 4.34Å; F226-F230 HydrophobicContact CE2-CG 4.36Å; F226-F230 HydrophobicContact CG-CD2 4.49Å; F226-F230 PolarHBondContact O-N 2.92Å; F226-L233 HydrophobicContact CE2-CD2 4.15Å; F226-L233 HydrophobicContact CZ-CD2 3.76Å; F226-L233 HydrophobicContact CZ-CG 4.03Å; F226-A234 HydrophobicContact CD1-CB 4.47Å; F226-A234 HydrophobicContact CE1-CB 4.15Å; F226-L237 HydrophobicContact CE1-CD1 4.06Å; F226-L237 HydrophobicContact CZ-CD1 4.08Å; F226-M239 HydrophobicContact CD1-CE 4.44Å; F226-M239 HydrophobicContact CD1-SD 3.85Å; F226-M239 HydrophobicContact CE1-SD 3.79Å
227M89.4Confident88.2Confident1 Ų167.2 Ų67.21%0.00532%0.323CS..Hα-helixtrans-64.6-44.7178.5-69.6-171.6-71.800112.9F106 L223 T224 S229 P231 A234 M239 M241F106-M227 HydrophobicContact CZ-SD 4.46Å; L223-M227 WeakPolarHBondContact O-CG 3.2Å; L223-M227 PolarHBondContact O-N 2.78Å; T224-M227 PolarHBondContact O-N 2.98Å; M227-S229 PolarHBondContact O-N 3.23Å; M227-P231 VanDerWaalsContact O-CA 3.24Å; M227-P231 WeakPolarHBondContact O-CA 3.18Å; M227-A234 HydrophobicContact CB-CB 4.22Å; M227-A234 HydrophobicContact CG-CB 3.86Å; M227-M239 HydrophobicContact CG-CB 4.41Å; M227-M239 HydrophobicContact CG-CE 3.68Å; M227-M239 HydrophobicContact CG-SD 3.82Å; M227-M239 HydrophobicContact SD-CB 3.88Å; M227-M239 HydrophobicContact SD-CE 3.84Å; M227-M239 HydrophobicContact SD-SD 4.33Å; M227-M241 HydrophobicContact CB-CE 3.82Å; M227-M241 HydrophobicContact CE-CE 3.78Å; M227-M241 HydrophobicContact CE-SD 3.52Å; M227-M241 VanDerWaalsContact CE-SD 3.52Å; M227-M241 HydrophobicContact SD-CE 4.04Å; M227-M241 HydrophobicContact SD-SD 4.38Å
228F84.8Confident88.6Confident66 Ų6671.5 Ų71.529%0.28934%0.337SS..Hα-helixtrans-63.3-36.2178-76.1-56.8000113.2T224 M241T224-F228 HydrophobicContact CG2-CD2 3.86Å; T224-F228 HydrophobicContact CG2-CE2 3.39Å; T224-F228 HydrophobicContact CG2-CZ 4.35Å; T224-F228 WeakPolarHBondContact O-CD2 3.29Å; T224-F228 PolarHBondContact O-N 2.8Å; F228-M241 HydrophobicContact CE1-CE 4.2Å; F228-M241 HydrophobicContact CZ-CE 4.18Å
229S85.8Confident88.8Confident10 Ų1068.8 Ų68.87%0.0733%0.328CS..Hα-helixtrans-76.2-43.1-175.4-87.70000115H77 M225 F226 M227 P231H77-S229 WeakPolarHBondContact CE1-CB 3.42Å; H77-S229 PolarHBondContact CE1-OG 2.88Å; H77-S229 PolarHBondContact ND1-OG 2.84Å; H77-S229 WeakPolarHBondContact NE2-CB 3.49Å; H77-S229 PolarHBondContact NE2-OG 3.48Å; M225-S229 WeakPolarHBondContact O-CB 3.3Å; M225-S229 PolarHBondContact O-N 3.29Å; M225-S229 PolarHBondContact O-OG 3.3Å; F226-S229 WeakPolarHBondContact O-CB 3.31Å; F226-S229 PolarHBondContact O-N 3.15Å; M227-S229 PolarHBondContact O-N 3.23Å; S229-P231 WeakPolarHBondContact O-CD 3.48Å
230F87.9Confident89Confident95 Ų9569.4 Ų69.442%0.41733%0.328SS..SBendtrans-12759.4-177.2-58.2-72.4000110.7H77 F226 K232 L233 A234H77-F230 AromaticContact CD2-CE1 3.93Å; H77-F230 AromaticContact CD2-CZ 3.63Å; H77-F230 AromaticContact CE1-CD2 3.55Å; H77-F230 AromaticContact CE1-CE2 3.02Å; H77-F230 WeakPolarHBondContact CE1-CE2 3.48Å; H77-F230 AromaticContact CE1-CZ 3.4Å; H77-F230 WeakPolarHBondContact CE1-CZ 3.24Å; H77-F230 AromaticContact NE2-CD1 3.76Å; H77-F230 AromaticContact NE2-CD2 3.47Å; H77-F230 WeakPolarHBondContact NE2-CD2 3.35Å; H77-F230 AromaticContact NE2-CE1 3.32Å; H77-F230 VanDerWaalsContact NE2-CE1 3.32Å; H77-F230 WeakPolarHBondContact NE2-CE1 3.34Å; H77-F230 AromaticContact NE2-CE2 3.03Å; H77-F230 WeakPolarHBondContact NE2-CE2 3.45Å; H77-F230 AromaticContact NE2-CG 3.84Å; H77-F230 AromaticContact NE2-CZ 2.95Å; H77-F230 WeakPolarHBondContact NE2-CZ 3.47Å; F226-F230 AromaticContact CD2-CD2 3.61Å; F226-F230 HydrophobicContact CD2-CD2 3.61Å; F226-F230 HydrophobicContact CD2-CE2 4.21Å; F226-F230 HydrophobicContact CE2-CB 4.35Å; F226-F230 AromaticContact CE2-CD2 3.67Å; F226-F230 HydrophobicContact CE2-CD2 3.67Å; F226-F230 HydrophobicContact CE2-CE2 4.34Å; F226-F230 HydrophobicContact CE2-CG 4.36Å; F226-F230 HydrophobicContact CG-CD2 4.49Å; F226-F230 PolarHBondContact O-N 2.92Å; F230-K232 VanDerWaalsContact C-N 3.3Å; F230-K232 PolarHBondContact O-N 3.49Å; F230-L233 HydrophobicContact CB-CB 4.06Å; F230-L233 PolarHBondContact O-N 3.16Å; F230-A234 PolarHBondContact O-N 3.45Å
231P88.9Confident89.1Confident26 Ų2669.2 Ų69.217%0.16932%0.319CS..Hα-helixtrans-60.2-38.6-168.121.5-33.6000113.1F106 M227 S229 L233 S235F106-P231 HydrophobicContact CB-CB 3.92Å; F106-P231 HydrophobicContact CD2-CB 4.1Å; M227-P231 VanDerWaalsContact O-CA 3.24Å; M227-P231 WeakPolarHBondContact O-CA 3.18Å; S229-P231 WeakPolarHBondContact O-CD 3.48Å; P231-L233 PolarHBondContact O-N 3.29Å; P231-S235 WeakPolarHBondContact O-CB 3.32Å; P231-S235 PolarHBondContact O-N 3.36Å
232K88.3Confident89.5Confident149 Ų14965.1 Ų65.165%0.64830%0.301SS*.Hα-helixtrans-64.5-38.5176.5-67.1-173.6177.6-1750112.6F230 R236F230-K232 VanDerWaalsContact C-N 3.3Å; F230-K232 PolarHBondContact O-N 3.49Å; K232-R236 VanDerWaalsContact O-CG 3.31Å; K232-R236 WeakPolarHBondContact O-CG 3.49Å; K232-R236 PolarHBondContact O-N 2.82Å
233L89.8Confident89.8Confident77 Ų7759.6 Ų59.640%0.40327%0.273SS..Hα-helixtrans-73.2-45.6179-178.858.9000110.4F226 F230 P231 S235 R236 L237F226-L233 HydrophobicContact CE2-CD2 4.15Å; F226-L233 HydrophobicContact CZ-CD2 3.76Å; F226-L233 HydrophobicContact CZ-CG 4.03Å; F230-L233 HydrophobicContact CB-CB 4.06Å; F230-L233 PolarHBondContact O-N 3.16Å; P231-L233 PolarHBondContact O-N 3.29Å; L233-S235 VanDerWaalsContact C-N 3.28Å; L233-S235 PolarHBondContact O-N 3.07Å; L233-R236 WeakPolarHBondContact O-CB 3.22Å; L233-R236 PolarHBondContact O-N 2.88Å; L233-R236 VanDerWaalsContact O-N 3.11Å; L233-L237 HydrophobicContact CD1-CD1 4.5Å; L233-L237 HydrophobicContact CD1-CG 4.45Å; L233-L237 HydrophobicContact CG-CD1 4.21Å; L233-L237 WeakPolarHBondContact O-CG 3.34Å; L233-L237 PolarHBondContact O-N 3.03Å
234A91.5Very high90Very high0 Ų058.6 Ų58.60%027%0.266CS..Hα-helixtrans-57.1-41.3175.300000112.5F106 F226 M227 F230 L237 R238 M239F106-A234 HydrophobicContact CD2-CB 4.06Å; F106-A234 HydrophobicContact CE2-CB 3.66Å; F226-A234 HydrophobicContact CD1-CB 4.47Å; F226-A234 HydrophobicContact CE1-CB 4.15Å; M227-A234 HydrophobicContact CB-CB 4.22Å; M227-A234 HydrophobicContact CG-CB 3.86Å; F230-A234 PolarHBondContact O-N 3.45Å; A234-L237 CarbonylContact O-C 3.54Å; A234-L237 PolarHBondContact O-N 2.84Å; A234-R238 PolarHBondContact O-N 3.3Å; A234-M239 HydrophobicContact CB-CB 4.44Å; A234-M239 HydrophobicContact CB-CG 4.46Å; A234-M239 HydrophobicContact CB-SD 3.84Å; A234-M239 PolarHBondContact O-N 3.09Å; A234-M239 VanDerWaalsContact O-N 3.12Å
235S89Confident90.2Very high42 Ų4261.2 Ų61.229%0.29428%0.28SS..Hα-helixtrans-64.3-41.7175.4178.90000111.7P231 L233 L237 R238P231-S235 WeakPolarHBondContact O-CB 3.32Å; P231-S235 PolarHBondContact O-N 3.36Å; L233-S235 VanDerWaalsContact C-N 3.28Å; L233-S235 PolarHBondContact O-N 3.07Å; S235-L237 VanDerWaalsContact C-N 3.28Å; S235-L237 PolarHBondContact O-N 3.11Å; S235-R238 PolarHBondContact O-N 2.68Å
236R91.1Very high90.6Very high199 Ų19959.8 Ų59.875%0.75127%0.273SS*.Hα-helixtrans-63.5-33.1173.7-72.8174.1-174.3173.3-0.2113K232 L233 R238K232-R236 VanDerWaalsContact O-CG 3.31Å; K232-R236 WeakPolarHBondContact O-CG 3.49Å; K232-R236 PolarHBondContact O-N 2.82Å; L233-R236 WeakPolarHBondContact O-CB 3.22Å; L233-R236 PolarHBondContact O-N 2.88Å; L233-R236 VanDerWaalsContact O-N 3.11Å; R236-R238 PolarHBondContact O-N 3.05Å
237L93Very high90.8Very high106 Ų10658 Ų5856%0.55527%0.266SS*.THydrogen-bonded Turntrans-78.45.1174.3-66175.2000113.3F226 L233 A234 S235 M239F226-L237 HydrophobicContact CE1-CD1 4.06Å; F226-L237 HydrophobicContact CZ-CD1 4.08Å; L233-L237 HydrophobicContact CD1-CD1 4.5Å; L233-L237 HydrophobicContact CD1-CG 4.45Å; L233-L237 HydrophobicContact CG-CD1 4.21Å; L233-L237 WeakPolarHBondContact O-CG 3.34Å; L233-L237 PolarHBondContact O-N 3.03Å; A234-L237 CarbonylContact O-C 3.54Å; A234-L237 PolarHBondContact O-N 2.84Å; S235-L237 VanDerWaalsContact C-N 3.28Å; S235-L237 PolarHBondContact O-N 3.11Å; L237-M239 HydrophobicContact CB-CG 4.15Å; L237-M239 PolarHBondContact O-N 2.81Å
238R93Very high91Very high142 Ų14261.7 Ų61.754%0.53628%0.283SS..THydrogen-bonded Turntrans5830.6179.2-54-170-174.4176.53.5113.9D111 A234 S235 R236D111-R238 WeakPolarHBondContact OD2-CB 3.48Å; D111-R238 WeakPolarHBondContact OD2-CG 3.37Å; A234-R238 PolarHBondContact O-N 3.3Å; S235-R238 PolarHBondContact O-N 2.68Å; R236-R238 PolarHBondContact O-N 3.05Å
239M93.8Very high91.4Very high25 Ų2560 Ų6012%0.12328%0.275CS..  trans-66.9150.6176.5-62.9-174.975.900110.8N108 L223 F226 M227 A234 L237N108-M239 PolarHBondContact ND2-O 2.97Å; N108-M239 VanDerWaalsContact ND2-O 3.08Å; L223-M239 HydrophobicContact CB-CE 4.13Å; L223-M239 HydrophobicContact CD2-CE 4.27Å; F226-M239 HydrophobicContact CD1-CE 4.44Å; F226-M239 HydrophobicContact CD1-SD 3.85Å; F226-M239 HydrophobicContact CE1-SD 3.79Å; M227-M239 HydrophobicContact CG-CB 4.41Å; M227-M239 HydrophobicContact CG-CE 3.68Å; M227-M239 HydrophobicContact CG-SD 3.82Å; M227-M239 HydrophobicContact SD-CB 3.88Å; M227-M239 HydrophobicContact SD-CE 3.84Å; M227-M239 HydrophobicContact SD-SD 4.33Å; A234-M239 HydrophobicContact CB-CB 4.44Å; A234-M239 HydrophobicContact CB-CG 4.46Å; A234-M239 HydrophobicContact CB-SD 3.84Å; A234-M239 PolarHBondContact O-N 3.09Å; A234-M239 VanDerWaalsContact O-N 3.12Å; L237-M239 HydrophobicContact CB-CG 4.15Å; L237-M239 PolarHBondContact O-N 2.81Å
240R93.1Very high91.7Very high76 Ų7659.5 Ų59.529%0.28727%0.272SS..  trans-116.5128.6176.1-60.1-175.1175.8-170.5-9.9108.8D111 D112 R218 H219 E244D111-R240 HydrophobicContact CB-CG 4.36Å; D111-R240 WeakPolarHBondContact O-CD 3.43Å; D111-R240 PolarHBondContact O-NE 2.78Å; D111-R240 PolarHBondContact O-NH2 3.12Å; D112-R240 HydrophobicContact CB-CB 4.15Å; D112-R240 HydrophobicContact CB-CG 4.13Å; R218-R240 WeakPolarHBondContact CD-O 3.34Å; H219-R240 PolarHBondContact CD2-O 3.47Å; H219-R240 PolarHBondContact NE2-O 3.05Å; R240-E244 IonicContact NH1-OE1 3.96Å; R240-E244 IonicContact NH1-OE2 2.79Å; R240-E244 PolarHBondContact NH1-OE2 2.81Å
241M91.4Very high92Very high29 Ų2956.2 Ų56.214%0.14326%0.258CS..  trans-80.5-41.6176-17467.272.600110.9F106 D112 T115 T224 M227 F228F106-M241 HydrophobicContact CB-CE 4.4Å; F106-M241 HydrophobicContact CD1-CB 4.12Å; F106-M241 HydrophobicContact CD1-CE 3.82Å; F106-M241 HydrophobicContact CE1-CB 3.89Å; F106-M241 HydrophobicContact CE1-CE 4.43Å; F106-M241 HydrophobicContact CG-CE 4.24Å; D112-M241 WeakPolarHBondContact OD2-CA 3.5Å; D112-M241 PolarHBondContact OD2-N 2.77Å; T115-M241 HydrophobicContact CG2-CB 4.03Å; T224-M241 HydrophobicContact CG2-SD 4.42Å; M227-M241 HydrophobicContact CB-CE 3.82Å; M227-M241 HydrophobicContact CE-CE 3.78Å; M227-M241 HydrophobicContact CE-SD 3.52Å; M227-M241 VanDerWaalsContact CE-SD 3.52Å; M227-M241 HydrophobicContact SD-CE 4.04Å; M227-M241 HydrophobicContact SD-SD 4.38Å; F228-M241 HydrophobicContact CE1-CE 4.2Å; F228-M241 HydrophobicContact CZ-CE 4.18Å
242M91.8Very high92.2Very high23 Ų2362 Ų6211%0.11328%0.276CS..SBendtrans-74135.9-172-64.2-64.295.300112.6D112 L114 T115 R218 H247 F305D112-M242 WeakPolarHBondContact OD1-CB 3.49Å; D112-M242 WeakPolarHBondContact OD1-CG 3.23Å; D112-M242 PolarHBondContact OD2-N 2.63Å; L114-M242 HydrophobicContact CB-CG 4.09Å; T115-M242 HydrophobicContact CG2-CG 4.28Å; R218-M242 VanDerWaalsContact CD-O 3.32Å; R218-M242 WeakPolarHBondContact CD-O 3.47Å; R218-M242 PolarHBondContact NH1-O 3.16Å; M242-H247 HydrophobicContact CB-CB 4.43Å; M242-F305 HydrophobicContact SD-CE1 3.9Å; M242-F305 HydrophobicContact SD-CE2 4.26Å; M242-F305 HydrophobicContact SD-CZ 3.48Å; M242-F305 WeakPolarHBondContact SD-CZ 3.39Å
243P92.6Very high92.3Very high11 Ų1156.3 Ų56.37%0.07125%0.253CS..  trans-51.7142.3165.2-24.934.9000111.1D216 D245 V246 H247D216-P243 HydrophobicContact CB-CG 4.04Å; P243-D245 VanDerWaalsContact CB-OD1 3.27Å; P243-D245 WeakPolarHBondContact CB-OD1 3.46Å; P243-D245 PolarHBondContact O-N 2.55Å; P243-V246 HydrophobicContact CB-CB 4.19Å; P243-V246 HydrophobicContact CB-CG2 3.95Å; P243-V246 HydrophobicContact CG-CG2 4.21Å; P243-V246 PolarHBondContact O-N 3.48Å; P243-H247 WeakPolarHBondContact O-CB 3.32Å; P243-H247 PolarHBondContact O-N 2.92Å
244E92.3Very high92.3Very high61 Ų6152.7 Ų52.729%0.28523%0.234SC..Hα-helixtrans-66.2-40.4-171.5-17161.6-147.700112.2R218 R240 H247 Q248R218-E244 IonicContact CZ-OE2 3.44Å; R218-E244 VanDerWaalsContact CZ-OE2 3.27Å; R218-E244 IonicContact NH1-OE2 3.34Å; R218-E244 PolarHBondContact NH1-OE2 2.75Å; R218-E244 IonicContact NH2-OE2 3.54Å; R218-E244 PolarHBondContact NH2-OE2 2.85Å; R240-E244 IonicContact NH1-OE1 3.96Å; R240-E244 IonicContact NH1-OE2 2.79Å; R240-E244 PolarHBondContact NH1-OE2 2.81Å; E244-H247 WeakPolarHBondContact O-CB 3.24Å; E244-H247 PolarHBondContact O-N 2.76Å; E244-H247 IonicContact OE1-CD2 3.45Å; E244-Q248 HydrophobicContact CG-CG 4.36Å; E244-Q248 WeakPolarHBondContact O-CB 3.25Å; E244-Q248 VanDerWaalsContact O-CG 3.23Å; E244-Q248 WeakPolarHBondContact O-CG 3.4Å; E244-Q248 PolarHBondContact O-N 2.75Å; E244-Q248 PolarHBondContact OE1-NE2 3.31Å
245D93.5Very high92.2Very high62 Ų6256 Ų5633%0.33225%0.252SS..Hα-helixtrans-62.6-43.8176.356.7-17.5000112.3M209 K212 P243 Q248 F249M209-D245 HydrophobicContact SD-CB 4.5Å; K212-D245 IonicContact NZ-OD2 2.69Å; K212-D245 PolarHBondContact NZ-OD2 3.18Å; P243-D245 VanDerWaalsContact CB-OD1 3.27Å; P243-D245 WeakPolarHBondContact CB-OD1 3.46Å; P243-D245 PolarHBondContact O-N 2.55Å; D245-Q248 PolarHBondContact O-N 3.1Å; D245-F249 VanDerWaalsContact O-CB 3.29Å; D245-F249 WeakPolarHBondContact O-CB 3.22Å; D245-F249 PolarHBondContact O-N 3.22Å
246V92.9Very high92.3Very high0 Ų059.1 Ų59.10%027%0.265CS..Hα-helixtrans-60.3-47.7173175.70000110.4M209 K212 V213 P243 Q248 F249 F250 F305M209-V246 HydrophobicContact SD-CG2 4.3Å; K212-V246 HydrophobicContact CB-CG2 3.73Å; K212-V246 HydrophobicContact CD-CG2 4.42Å; V213-V246 HydrophobicContact CG2-CG1 3.95Å; P243-V246 HydrophobicContact CB-CB 4.19Å; P243-V246 HydrophobicContact CB-CG2 3.95Å; P243-V246 HydrophobicContact CG-CG2 4.21Å; P243-V246 PolarHBondContact O-N 3.48Å; V246-Q248 PolarHBondContact O-N 3.18Å; V246-F249 PolarHBondContact O-N 3.01Å; V246-F250 HydrophobicContact CG1-CD2 3.91Å; V246-F250 HydrophobicContact CG1-CE2 3.94Å; V246-F250 WeakPolarHBondContact O-CD2 3.12Å; V246-F250 PolarHBondContact O-N 2.96Å; V246-F250 VanDerWaalsContact O-N 3.16Å; V246-F305 HydrophobicContact CG1-CE2 4.02Å
247H93.4Very high92.1Very high19 Ų1950.4 Ų50.49%0.08823%0.234CC..Hα-helixtrans-56.1-53.3177.3175.577.4000111.7L114 M242 P243 E244 F249 F250 M251L114-H247 HydrophobicContact CD1-CB 4.45Å; M242-H247 HydrophobicContact CB-CB 4.43Å; P243-H247 WeakPolarHBondContact O-CB 3.32Å; P243-H247 PolarHBondContact O-N 2.92Å; E244-H247 WeakPolarHBondContact O-CB 3.24Å; E244-H247 PolarHBondContact O-N 2.76Å; E244-H247 IonicContact OE1-CD2 3.45Å; H247-F249 VanDerWaalsContact C-N 3.29Å; H247-F249 PolarHBondContact O-N 2.72Å; H247-F250 PolarHBondContact O-N 3.06Å; H247-M251 WeakPolarHBondContact O-CB 3.29Å; H247-M251 VanDerWaalsContact O-CG 3.25Å; H247-M251 WeakPolarHBondContact O-CG 3.4Å; H247-M251 PolarHBondContact O-N 2.98Å
248Q94.1Very high91.8Very high77 Ų7745.9 Ų45.936%0.3621%0.21SC..Hα-helixtrans-63.9-33.9-179.4-67.2-59.8-28.800112.5E244 D245 V246 R252E244-Q248 HydrophobicContact CG-CG 4.36Å; E244-Q248 WeakPolarHBondContact O-CB 3.25Å; E244-Q248 VanDerWaalsContact O-CG 3.23Å; E244-Q248 WeakPolarHBondContact O-CG 3.4Å; E244-Q248 PolarHBondContact O-N 2.75Å; E244-Q248 PolarHBondContact OE1-NE2 3.31Å; D245-Q248 PolarHBondContact O-N 3.1Å; V246-Q248 PolarHBondContact O-N 3.18Å; Q248-R252 VanDerWaalsContact O-CB 3.29Å; Q248-R252 WeakPolarHBondContact O-CB 3.27Å; Q248-R252 VanDerWaalsContact O-CG 3.24Å; Q248-R252 WeakPolarHBondContact O-CG 3.28Å; Q248-R252 PolarHBondContact O-N 3.14Å; Q248-R252 PolarHBondContact O-NE 3.16Å; Q248-R252 VanDerWaalsContact O-NE 3.11Å
249F92.8Very high91.5Very high31 Ų3141.9 Ų41.914%0.13621%0.208CC..Hα-helixtrans-63.6-56.3177.4178.2-99.3000111.9D205 F206 M209 D245 V246 H247 M251 R252 L253D205-F249 HydrophobicContact CB-CE2 3.82Å; D205-F249 HydrophobicContact CB-CZ 4.38Å; F206-F249 HydrophobicContact CB-CZ 4.24Å; F206-F249 AromaticContact CD2-CE1 3.75Å; F206-F249 HydrophobicContact CD2-CE1 3.75Å; F206-F249 AromaticContact CD2-CZ 3.79Å; F206-F249 HydrophobicContact CD2-CZ 3.79Å; F206-F249 HydrophobicContact CE2-CE1 4.38Å; F206-F249 HydrophobicContact CG-CZ 4.49Å; M209-F249 HydrophobicContact CB-CD1 3.75Å; M209-F249 HydrophobicContact CB-CE1 4.11Å; M209-F249 HydrophobicContact CB-CG 4.09Å; M209-F249 HydrophobicContact CG-CB 3.94Å; M209-F249 HydrophobicContact CG-CD1 3.81Å; M209-F249 HydrophobicContact CG-CD2 3.94Å; M209-F249 HydrophobicContact CG-CE1 4.29Å; M209-F249 HydrophobicContact CG-CE2 4.41Å; M209-F249 HydrophobicContact CG-CG 3.62Å; M209-F249 HydrophobicContact SD-CB 4.35Å; D245-F249 VanDerWaalsContact O-CB 3.29Å; D245-F249 WeakPolarHBondContact O-CB 3.22Å; D245-F249 PolarHBondContact O-N 3.22Å; V246-F249 PolarHBondContact O-N 3.01Å; H247-F249 VanDerWaalsContact C-N 3.29Å; H247-F249 PolarHBondContact O-N 2.72Å; F249-M251 PolarHBondContact O-N 3.23Å; F249-R252 PolarHBondContact O-N 3.38Å; F249-L253 HydrophobicContact CE1-CD2 4.37Å; F249-L253 VanDerWaalsContact O-CB 3.32Å; F249-L253 WeakPolarHBondContact O-CB 3.42Å; F249-L253 PolarHBondContact O-N 2.75Å
250F92.1Very high91.2Very high0 Ų044.3 Ų44.30%022%0.221CC..Hα-helixtrans-68.3-35.2-177.2-76-77.8000112.6L114 F206 M209 V246 H247 L253 V254 F305 Y308L114-F250 HydrophobicContact CD1-CB 3.95Å; L114-F250 HydrophobicContact CD1-CD2 4.41Å; L114-F250 HydrophobicContact CD2-CB 4.15Å; F206-F250 HydrophobicContact CE2-CE1 4.37Å; M209-F250 HydrophobicContact CB-CE2 4.32Å; V246-F250 HydrophobicContact CG1-CD2 3.91Å; V246-F250 HydrophobicContact CG1-CE2 3.94Å; V246-F250 WeakPolarHBondContact O-CD2 3.12Å; V246-F250 PolarHBondContact O-N 2.96Å; V246-F250 VanDerWaalsContact O-N 3.16Å; H247-F250 PolarHBondContact O-N 3.06Å; F250-L253 HydrophobicContact CD1-CD2 4.4Å; F250-V254 WeakPolarHBondContact O-CB 3.4Å; F250-V254 WeakPolarHBondContact O-CG2 3.34Å; F250-V254 PolarHBondContact O-N 3.32Å; F250-V254 VanDerWaalsContact O-N 3.16Å; F250-F305 HydrophobicContact CD1-CB 4.33Å; F250-F305 HydrophobicContact CD1-CD2 4.29Å; F250-F305 AromaticContact CD2-CD2 3.55Å; F250-F305 HydrophobicContact CD2-CD2 3.55Å; F250-F305 HydrophobicContact CD2-CE2 4.13Å; F250-F305 HydrophobicContact CE1-CD2 4.38Å; F250-F305 AromaticContact CE2-CD2 3.68Å; F250-F305 HydrophobicContact CE2-CD2 3.68Å; F250-F305 HydrophobicContact CE2-CE2 4.02Å; F250-F305 HydrophobicContact CG-CB 4.31Å; F250-F305 AromaticContact CG-CD2 3.91Å; F250-F305 HydrophobicContact CG-CD2 3.91Å; F250-F305 HydrophobicContact CZ-CD2 4.12Å; F250-Y308 AromaticContact CE1-CD1 3.62Å; F250-Y308 HydrophobicContact CE1-CD1 3.62Å; F250-Y308 HydrophobicContact CE1-CE1 4.28Å; F250-Y308 HydrophobicContact CE1-CG 4.21Å; F250-Y308 AromaticContact CZ-CD1 3.35Å; F250-Y308 HydrophobicContact CZ-CD1 3.35Å; F250-Y308 AromaticContact CZ-CE1 3.7Å; F250-Y308 HydrophobicContact CZ-CE1 3.7Å; F250-Y308 HydrophobicContact CZ-CG 4.35Å
251M93.9Very high90.8Very high26 Ų2642 Ų4213%0.12821%0.212CC..Hα-helixtrans-63.3-45.9173.9-70.4-58.1-60.300111.5P113 L114 H247 F249 N255 A301P113-M251 HydrophobicContact CB-SD 4.41Å; L114-M251 HydrophobicContact CD2-SD 4.12Å; H247-M251 WeakPolarHBondContact O-CB 3.29Å; H247-M251 VanDerWaalsContact O-CG 3.25Å; H247-M251 WeakPolarHBondContact O-CG 3.4Å; H247-M251 PolarHBondContact O-N 2.98Å; F249-M251 PolarHBondContact O-N 3.23Å; M251-N255 PolarHBondContact O-N 2.82Å; M251-N255 VanDerWaalsContact O-N 3.13Å; M251-N255 PolarHBondContact O-ND2 3.29Å; M251-A301 HydrophobicContact CE-CB 4.44Å; M251-A301 HydrophobicContact SD-CB 3.51Å; M251-A301 VanDerWaalsContact SD-CB 3.51Å
252R93Very high90.4Very high146 Ų14645.6 Ų45.655%0.55123%0.229SC*.Hα-helixtrans-64.6-48.9177.2-76.4-177.4-66.9177.62.4111.7Q248 F249 V254 N255 D256Q248-R252 VanDerWaalsContact O-CB 3.29Å; Q248-R252 WeakPolarHBondContact O-CB 3.27Å; Q248-R252 VanDerWaalsContact O-CG 3.24Å; Q248-R252 WeakPolarHBondContact O-CG 3.28Å; Q248-R252 PolarHBondContact O-N 3.14Å; Q248-R252 PolarHBondContact O-NE 3.16Å; Q248-R252 VanDerWaalsContact O-NE 3.11Å; F249-R252 PolarHBondContact O-N 3.38Å; R252-V254 PolarHBondContact O-N 2.88Å; R252-V254 VanDerWaalsContact O-N 3.15Å; R252-N255 PolarHBondContact O-N 3.35Å; R252-N255 VanDerWaalsContact O-N 3.09Å; R252-D256 WeakPolarHBondContact O-CB 3.48Å; R252-D256 PolarHBondContact O-N 3.09Å
253L89.5Confident90.1Very high31 Ų3153.2 Ų53.216%0.16226%0.256CS..Hα-helixtrans-49.4-47.4179.1178.766.4000112.2I194 F206 F249 F250 T257I194-L253 HydrophobicContact CD1-CD1 3.71Å; I194-L253 HydrophobicContact CD1-CD2 4.31Å; I194-L253 HydrophobicContact CD1-CG 4.35Å; F206-L253 HydrophobicContact CD2-CD2 4.13Å; F206-L253 HydrophobicContact CE2-CD2 3.59Å; F249-L253 HydrophobicContact CE1-CD2 4.37Å; F249-L253 VanDerWaalsContact O-CB 3.32Å; F249-L253 WeakPolarHBondContact O-CB 3.42Å; F249-L253 PolarHBondContact O-N 2.75Å; F250-L253 HydrophobicContact CD1-CD2 4.4Å; L253-T257 VanDerWaalsContact O-CB 3.27Å; L253-T257 WeakPolarHBondContact O-CB 3.49Å; L253-T257 PolarHBondContact O-N 3.42Å; L253-T257 PolarHBondContact O-OG1 3.12Å
254V90Very high89.8Confident0 Ų057.8 Ų57.80%028%0.277CS..Hα-helixtrans-69.5-45.5-177.91700000111.3F250 R252 T257 I258 M272 I297 L300 A301 V304F250-V254 WeakPolarHBondContact O-CB 3.4Å; F250-V254 WeakPolarHBondContact O-CG2 3.34Å; F250-V254 PolarHBondContact O-N 3.32Å; F250-V254 VanDerWaalsContact O-N 3.16Å; R252-V254 PolarHBondContact O-N 2.88Å; R252-V254 VanDerWaalsContact O-N 3.15Å; V254-T257 PolarHBondContact O-N 2.9Å; V254-I258 HydrophobicContact CG1-CD1 3.87Å; V254-I258 WeakPolarHBondContact O-CB 3.46Å; V254-I258 VanDerWaalsContact O-CG1 3.28Å; V254-I258 WeakPolarHBondContact O-CG1 3.33Å; V254-I258 PolarHBondContact O-N 3.21Å; V254-M272 HydrophobicContact CG2-CE 4.4Å; V254-I297 HydrophobicContact CG1-CD1 3.77Å; V254-L300 HydrophobicContact CG1-CD2 3.31Å; V254-A301 HydrophobicContact CB-CB 4.18Å; V254-A301 HydrophobicContact CG1-CB 4.2Å; V254-A301 HydrophobicContact CG2-CB 3.97Å; V254-V304 HydrophobicContact CG2-CB 3.93Å; V254-V304 HydrophobicContact CG2-CG1 3.75Å; V254-V304 HydrophobicContact CG2-CG2 4.07Å
255N91Very high89.1Confident71 Ų7161.6 Ų61.638%0.3830%0.299SS..Hα-helixtrans-60-48.5176.5-80.1-59.9000111.7M251 R252 T257 I258 A259 I297M251-N255 PolarHBondContact O-N 2.82Å; M251-N255 VanDerWaalsContact O-N 3.13Å; M251-N255 PolarHBondContact O-ND2 3.29Å; R252-N255 PolarHBondContact O-N 3.35Å; R252-N255 VanDerWaalsContact O-N 3.09Å; N255-T257 VanDerWaalsContact C-N 3.34Å; N255-T257 PolarHBondContact O-N 3.27Å; N255-I258 PolarHBondContact O-N 3.37Å; N255-A259 WeakPolarHBondContact O-CB 3.48Å; N255-A259 PolarHBondContact O-N 3.08Å; N255-I297 WeakPolarHBondContact OD1-CG1 3.43Å
256D89.6Confident88.2Confident106 Ų10664.4 Ų64.457%0.56731%0.308SS*.Hα-helixtrans-63.9-41.4-178.8-63.7-19.5000110.8R252 A259 L260R252-D256 WeakPolarHBondContact O-CB 3.48Å; R252-D256 PolarHBondContact O-N 3.09Å; D256-A259 PolarHBondContact O-N 3.04Å; D256-L260 VanDerWaalsContact O-CB 3.22Å; D256-L260 WeakPolarHBondContact O-CB 3.45Å; D256-L260 PolarHBondContact O-N 3.38Å
257T87.3Confident87.2Confident17 Ų1770.9 Ų70.910%0.10434%0.337CS..Hα-helixtrans-64.9-41.6177.8-580000112L253 V254 N255 R261 M272L253-T257 VanDerWaalsContact O-CB 3.27Å; L253-T257 WeakPolarHBondContact O-CB 3.49Å; L253-T257 PolarHBondContact O-N 3.42Å; L253-T257 PolarHBondContact O-OG1 3.12Å; V254-T257 PolarHBondContact O-N 2.9Å; N255-T257 VanDerWaalsContact C-N 3.34Å; N255-T257 PolarHBondContact O-N 3.27Å; T257-R261 VanDerWaalsContact O-CG 3.31Å; T257-R261 WeakPolarHBondContact O-CG 3.3Å; T257-R261 PolarHBondContact O-N 2.83Å; T257-R261 VanDerWaalsContact O-N 3.13Å; T257-M272 HydrophobicContact CG2-CE 4.07Å; T257-M272 HydrophobicContact CG2-CG 3.85Å; T257-M272 HydrophobicContact CG2-SD 4.37Å
258I86.3Confident86.2Confident10 Ų1073.2 Ų73.25%0.05135%0.345CS..Hα-helixtrans-66.5-49.4177.2-70.3169.5000110.1V254 N255 L260 R261 E262 I276 I297 L300V254-I258 HydrophobicContact CG1-CD1 3.87Å; V254-I258 WeakPolarHBondContact O-CB 3.46Å; V254-I258 VanDerWaalsContact O-CG1 3.28Å; V254-I258 WeakPolarHBondContact O-CG1 3.33Å; V254-I258 PolarHBondContact O-N 3.21Å; N255-I258 PolarHBondContact O-N 3.37Å; I258-L260 VanDerWaalsContact C-N 3.29Å; I258-L260 PolarHBondContact O-N 3Å; I258-R261 PolarHBondContact O-N 3.16Å; I258-E262 HydrophobicContact CG2-CG 4.25Å; I258-E262 WeakPolarHBondContact O-CB 3.5Å; I258-E262 WeakPolarHBondContact O-CG 3.49Å; I258-E262 PolarHBondContact O-N 3.09Å; I258-I276 HydrophobicContact CG1-CD1 4.08Å; I258-I276 HydrophobicContact CG1-CG1 3.99Å; I258-I297 HydrophobicContact CD1-CD1 3.44Å; I258-I297 VanDerWaalsContact CD1-CD1 3.44Å; I258-L300 HydrophobicContact CD1-CD1 4.05Å; I258-L300 HydrophobicContact CD1-CD2 4.11Å
259A87.9Confident84.9Confident58 Ų5874.9 Ų74.948%0.47936%0.356SS..Hα-helixtrans-58.8-41.5-18000000111.8N255 D256 R263N255-A259 WeakPolarHBondContact O-CB 3.48Å; N255-A259 PolarHBondContact O-N 3.08Å; D256-A259 PolarHBondContact O-N 3.04Å; A259-R263 VanDerWaalsContact O-CB 3.23Å; A259-R263 WeakPolarHBondContact O-CB 3.21Å; A259-R263 PolarHBondContact O-N 3.17Å
260L85.8Confident84.3Confident76 Ų7674 Ų7440%0.39835%0.353SS..Hα-helixtrans-61.4-49.4176-177.266.9000111.8D256 I258 R263 E264D256-L260 VanDerWaalsContact O-CB 3.22Å; D256-L260 WeakPolarHBondContact O-CB 3.45Å; D256-L260 PolarHBondContact O-N 3.38Å; I258-L260 VanDerWaalsContact C-N 3.29Å; I258-L260 PolarHBondContact O-N 3Å; L260-R263 VanDerWaalsContact CD1-NH2 3.31Å; L260-R263 PolarHBondContact O-N 3.2Å; L260-E264 VanDerWaalsContact CD1-CD 3.47Å; L260-E264 HydrophobicContact CD1-CG 4.22Å; L260-E264 WeakPolarHBondContact CD1-OE1 3.34Å; L260-E264 WeakPolarHBondContact O-CB 3.46Å; L260-E264 PolarHBondContact O-N 3.34Å
261R85.4Confident83.7Confident28 Ų2874.4 Ų74.411%0.10635%0.354CS..Hα-helixtrans-67.4-38.4-177.9-71.8177.6-172.9-149.61.1112.5F192 T257 I258 N265 D270F192-R261 PolarHBondContact O-NH2 3.04Å; T257-R261 VanDerWaalsContact O-CG 3.31Å; T257-R261 WeakPolarHBondContact O-CG 3.3Å; T257-R261 PolarHBondContact O-N 2.83Å; T257-R261 VanDerWaalsContact O-N 3.13Å; I258-R261 PolarHBondContact O-N 3.16Å; R261-N265 WeakPolarHBondContact O-CA 3.42Å; R261-N265 PolarHBondContact O-N 3.14Å; R261-D270 IonicContact CZ-OD1 3.18Å; R261-D270 IonicContact CZ-OD2 3.22Å; R261-D270 IonicContact NH1-OD1 3.21Å; R261-D270 PolarHBondContact NH1-OD1 2.82Å; R261-D270 IonicContact NH1-OD2 2.64Å; R261-D270 PolarHBondContact NH1-OD2 2.71Å; R261-D270 IonicContact NH2-OD1 2.79Å; R261-D270 PolarHBondContact NH2-OD1 2.94Å; R261-D270 IonicContact NH2-OD2 3.01Å; R261-D270 PolarHBondContact NH2-OD2 3.04Å
262E83.2Confident83.2Confident105 Ų10573.2 Ų73.249%0.49135%0.348SS..Hα-helixtrans-65.6-40.1174.5-72.2179.8169.100111.1I258I258-E262 HydrophobicContact CG2-CG 4.25Å; I258-E262 WeakPolarHBondContact O-CB 3.5Å; I258-E262 WeakPolarHBondContact O-CG 3.49Å; I258-E262 PolarHBondContact O-N 3.09Å
263R86.6Confident82.7Confident183 Ų18366.9 Ų66.969%0.69133%0.325SS*.Hα-helixtrans-67.8-44.8177.6-174.4-174.772.4-178.13113.1A259 L260A259-R263 VanDerWaalsContact O-CB 3.23Å; A259-R263 WeakPolarHBondContact O-CB 3.21Å; A259-R263 PolarHBondContact O-N 3.17Å; L260-R263 VanDerWaalsContact CD1-NH2 3.31Å; L260-R263 PolarHBondContact O-N 3.2Å
264E84.9Confident82.1Confident107 Ų10767.5 Ų67.550%0.533%0.329SS..Hα-helixtrans-90.1-5.3-172.8-65.8-177.6-177.300113.3L260 F266L260-E264 VanDerWaalsContact CD1-CD 3.47Å; L260-E264 HydrophobicContact CD1-CG 4.22Å; L260-E264 WeakPolarHBondContact CD1-OE1 3.34Å; L260-E264 WeakPolarHBondContact O-CB 3.46Å; L260-E264 PolarHBondContact O-N 3.34Å; E264-F266 HydrophobicContact CB-CB 4.5Å; E264-F266 PolarHBondContact O-N 2.91Å
265N78Confident81.7Confident141 Ų14167.5 Ų67.575%0.75433%0.329SS*.THydrogen-bonded Turntrans48.932.2-177-164.432.6000113.3R261R261-N265 WeakPolarHBondContact O-CA 3.42Å; R261-N265 PolarHBondContact O-N 3.14Å
266F75.4Confident81.3Confident120 Ų12064.5 Ų64.553%0.52631%0.313SS..  trans-98.8132.5-180163.8-105.2000110.2E264 R268E264-F266 HydrophobicContact CB-CB 4.5Å; E264-F266 PolarHBondContact O-N 2.91Å; F266-R268 HydrophobicContact CE1-CB 3.7Å; F266-R268 HydrophobicContact CZ-CB 3.77Å; F266-R268 HydrophobicContact CZ-CG 4.39Å
267K71.1Confident80.8Confident137 Ų13762.3 Ų62.360%0.59630%0.299SS*.  trans-109.3124.2175.2-65.6-173.3179.6-1740110
268R71.3Confident80.2Confident68 Ų6862.2 Ų62.226%0.25730%0.298SS..  trans-107.4134166.9-171.8168.3175.8159.25.6108.4T189 G193 F266 D270 N273T189-R268 VanDerWaalsContact CG2-NH2 3.26Å; G193-R268 VanDerWaalsContact C-NH1 3.3Å; G193-R268 PolarHBondContact O-NH1 3.29Å; F266-R268 HydrophobicContact CE1-CB 3.7Å; F266-R268 HydrophobicContact CZ-CB 3.77Å; F266-R268 HydrophobicContact CZ-CG 4.39Å; R268-D270 WeakPolarHBondContact CB-OD2 3.49Å; R268-D270 VanDerWaalsContact CD-OD2 3.29Å; R268-D270 WeakPolarHBondContact CD-OD2 3.49Å; R268-D270 HydrophobicContact CG-CB 4.33Å; R268-D270 VanDerWaalsContact CG-OD2 3.32Å; R268-D270 WeakPolarHBondContact CG-OD2 3.35Å; R268-D270 IonicContact NE-OD2 3.07Å; R268-D270 PolarHBondContact O-N 2.76Å; R268-N273 WeakPolarHBondContact O-CB 3.48Å
269N68.8Low79.8Confident112 Ų11265.2 Ų65.260%0.59931%0.31SS*.SBendtrans-78.164.8179.4-70.2-41.3000111.4F144F144-N269 HydrophobicContact CE1-CB 3.47Å; F144-N269 VanDerWaalsContact CE1-CB 3.47Å; F144-N269 WeakPolarHBondContact CE1-O 3.33Å; F144-N269 HydrophobicContact CZ-CB 3.44Å; F144-N269 VanDerWaalsContact CZ-CB 3.44Å
270D78.4Confident79.1Confident12 Ų1268 Ų686%0.06431%0.314CS..SBendtrans-119.8176.7179.457.932.7000112.1C190 G193 R261 R268 M272 N273 L274C190-D270 WeakPolarHBondContact O-CB 3.31Å; G193-D270 WeakPolarHBondContact CA-OD2 3.28Å; G193-D270 PolarHBondContact N-OD2 3.01Å; R261-D270 IonicContact CZ-OD1 3.18Å; R261-D270 IonicContact CZ-OD2 3.22Å; R261-D270 IonicContact NH1-OD1 3.21Å; R261-D270 PolarHBondContact NH1-OD1 2.82Å; R261-D270 IonicContact NH1-OD2 2.64Å; R261-D270 PolarHBondContact NH1-OD2 2.71Å; R261-D270 IonicContact NH2-OD1 2.79Å; R261-D270 PolarHBondContact NH2-OD1 2.94Å; R261-D270 IonicContact NH2-OD2 3.01Å; R261-D270 PolarHBondContact NH2-OD2 3.04Å; R268-D270 WeakPolarHBondContact CB-OD2 3.49Å; R268-D270 VanDerWaalsContact CD-OD2 3.29Å; R268-D270 WeakPolarHBondContact CD-OD2 3.49Å; R268-D270 HydrophobicContact CG-CB 4.33Å; R268-D270 VanDerWaalsContact CG-OD2 3.32Å; R268-D270 WeakPolarHBondContact CG-OD2 3.35Å; R268-D270 IonicContact NE-OD2 3.07Å; R268-D270 PolarHBondContact O-N 2.76Å; D270-M272 VanDerWaalsContact C-N 3.3Å; D270-M272 PolarHBondContact O-N 2.98Å; D270-M272 WeakPolarHBondContact OD1-CB 3.09Å; D270-M272 PolarHBondContact OD1-N 2.96Å; D270-N273 PolarHBondContact O-N 2.63Å; D270-N273 WeakPolarHBondContact OD1-CB 3.44Å; D270-N273 PolarHBondContact OD1-N 3.07Å; D270-L274 PolarHBondContact O-N 3.15Å
271F80.1Confident78.3Confident9 Ų970.7 Ų70.74%0.03932%0.322CS..Hα-helixtrans-62.7-37.5179.1177-118.8000112.1L133 T136 A191 F192 N273 L274 L275 F307L133-F271 HydrophobicContact CD2-CE2 3.7Å; L133-F271 HydrophobicContact CD2-CZ 3.76Å; T136-F271 HydrophobicContact CG2-CD2 3.47Å; T136-F271 VanDerWaalsContact CG2-CD2 3.47Å; T136-F271 HydrophobicContact CG2-CE2 4.08Å; T136-F271 HydrophobicContact CG2-CG 4.39Å; A191-F271 HydrophobicContact CB-CB 4Å; A191-F271 HydrophobicContact CB-CD1 4.29Å; A191-F271 CarbonylContact O-C 3.53Å; A191-F271 WeakPolarHBondContact O-CA 3.49Å; A191-F271 VanDerWaalsContact O-CB 3.28Å; A191-F271 WeakPolarHBondContact O-CB 3.37Å; A191-F271 PolarHBondContact O-N 2.91Å; A191-F271 VanDerWaalsContact O-N 3.14Å; F192-F271 HydrophobicContact CE1-CD1 4.36Å; F271-N273 VanDerWaalsContact C-N 3.33Å; F271-N273 PolarHBondContact O-N 3.31Å; F271-L274 HydrophobicContact CD2-CD2 4.44Å; F271-L274 WeakPolarHBondContact O-CB 3.49Å; F271-L274 PolarHBondContact O-N 3.1Å; F271-L275 HydrophobicContact CD1-CD1 4.02Å; F271-L275 HydrophobicContact CD1-CG 4.43Å; F271-L275 HydrophobicContact CD2-CG 4.47Å; F271-L275 HydrophobicContact CE1-CD1 3.55Å; F271-L275 HydrophobicContact CE1-CD2 4.3Å; F271-L275 HydrophobicContact CE1-CG 4.06Å; F271-L275 HydrophobicContact CE2-CD2 3.92Å; F271-L275 HydrophobicContact CE2-CG 4.13Å; F271-L275 HydrophobicContact CZ-CD1 3.82Å; F271-L275 HydrophobicContact CZ-CD2 3.69Å; F271-L275 HydrophobicContact CZ-CG 3.9Å; F271-L275 WeakPolarHBondContact O-CG 3.4Å; F271-L275 PolarHBondContact O-N 3.03Å; F271-F307 HydrophobicContact CD1-CD2 4.38Å; F271-F307 HydrophobicContact CE1-CB 4.05Å; F271-F307 AromaticContact CE1-CD2 3.27Å; F271-F307 HydrophobicContact CE1-CD2 3.27Å; F271-F307 AromaticContact CE1-CE2 3.91Å; F271-F307 HydrophobicContact CE1-CE2 3.91Å; F271-F307 AromaticContact CE1-CG 3.8Å; F271-F307 HydrophobicContact CE1-CG 3.8Å; F271-F307 HydrophobicContact CE2-CD2 4.3Å; F271-F307 HydrophobicContact CE2-CE2 4.16Å; F271-F307 AromaticContact CZ-CD2 3.22Å; F271-F307 HydrophobicContact CZ-CD2 3.22Å; F271-F307 AromaticContact CZ-CE2 3.31Å; F271-F307 HydrophobicContact CZ-CE2 3.31Å; F271-F307 HydrophobicContact CZ-CG 4.01Å; F271-F307 HydrophobicContact CZ-CZ 4.15Å
272M83.6Confident77.2Confident0 Ų071.1 Ų71.10%034%0.336CS..Hα-helixtrans-58.4-42.5174.9-178.86776.100112A191 F192 V254 T257 D270 L274 L275 I276 L300 V304A191-M272 PolarHBondContact O-N 3.28Å; F192-M272 HydrophobicContact CD1-CE 4.34Å; V254-M272 HydrophobicContact CG2-CE 4.4Å; T257-M272 HydrophobicContact CG2-CE 4.07Å; T257-M272 HydrophobicContact CG2-CG 3.85Å; T257-M272 HydrophobicContact CG2-SD 4.37Å; D270-M272 VanDerWaalsContact C-N 3.3Å; D270-M272 PolarHBondContact O-N 2.98Å; D270-M272 WeakPolarHBondContact OD1-CB 3.09Å; D270-M272 PolarHBondContact OD1-N 2.96Å; M272-L274 VanDerWaalsContact C-N 3.33Å; M272-L274 PolarHBondContact O-N 3.35Å; M272-L275 PolarHBondContact O-N 3.28Å; M272-L275 VanDerWaalsContact O-N 3.16Å; M272-I276 HydrophobicContact CG-CD1 3.91Å; M272-I276 HydrophobicContact CG-CG1 4.48Å; M272-I276 VanDerWaalsContact O-CG1 3.29Å; M272-I276 WeakPolarHBondContact O-CG1 3.48Å; M272-I276 PolarHBondContact O-N 3.39Å; M272-I276 HydrophobicContact SD-CD1 4.46Å; M272-L300 HydrophobicContact SD-CD2 3.92Å; M272-V304 HydrophobicContact CE-CG1 4.4Å; M272-V304 HydrophobicContact CE-CG2 3.7Å; M272-V304 HydrophobicContact SD-CG2 4.24Å
273N82.4Confident76.4Confident13 Ų1374.4 Ų74.47%0.0734%0.343CS..Hα-helixtrans-64.6-38.5177.8-173.581.6000111.9R268 D270 F271 L275 I276 E277R268-N273 WeakPolarHBondContact O-CB 3.48Å; D270-N273 PolarHBondContact O-N 2.63Å; D270-N273 WeakPolarHBondContact OD1-CB 3.44Å; D270-N273 PolarHBondContact OD1-N 3.07Å; F271-N273 VanDerWaalsContact C-N 3.33Å; F271-N273 PolarHBondContact O-N 3.31Å; N273-L275 VanDerWaalsContact C-N 3.32Å; N273-L275 PolarHBondContact O-N 2.96Å; N273-I276 PolarHBondContact O-N 3.43Å; N273-E277 PolarHBondContact ND2-OE1 2.91Å; N273-E277 WeakPolarHBondContact O-CG 3.4Å; N273-E277 PolarHBondContact O-N 3.32Å
274L77.7Confident75.5Confident44 Ų4467.1 Ų67.123%0.2332%0.319CS..Hα-helixtrans-60.5-43.8172.7-178.271.4000111.4T136 D270 F271 M272 I276 E277 L278T136-L274 HydrophobicContact CG2-CD2 4Å; T136-L274 WeakPolarHBondContact OG1-CD2 3.13Å; D270-L274 PolarHBondContact O-N 3.15Å; F271-L274 HydrophobicContact CD2-CD2 4.44Å; F271-L274 WeakPolarHBondContact O-CB 3.49Å; F271-L274 PolarHBondContact O-N 3.1Å; M272-L274 VanDerWaalsContact C-N 3.33Å; M272-L274 PolarHBondContact O-N 3.35Å; L274-I276 VanDerWaalsContact C-N 3.34Å; L274-I276 PolarHBondContact O-N 3.28Å; L274-E277 PolarHBondContact O-N 3.23Å; L274-L278 HydrophobicContact CG-CD1 4.31Å; L274-L278 VanDerWaalsContact O-CG 3.27Å; L274-L278 WeakPolarHBondContact O-CG 3.06Å; L274-L278 PolarHBondContact O-N 2.88Å
275L81.8Confident74.8Confident0 Ų066.6 Ų66.60%032%0.323CS..Hα-helixtrans-64.9-38.5177.7-63.6179.8000112.2L133 F271 M272 N273 L278 K279 M295 L300 Q303 V304L133-L275 HydrophobicContact CD2-CD2 3.81Å; F271-L275 HydrophobicContact CD1-CD1 4.02Å; F271-L275 HydrophobicContact CD1-CG 4.43Å; F271-L275 HydrophobicContact CD2-CG 4.47Å; F271-L275 HydrophobicContact CE1-CD1 3.55Å; F271-L275 HydrophobicContact CE1-CD2 4.3Å; F271-L275 HydrophobicContact CE1-CG 4.06Å; F271-L275 HydrophobicContact CE2-CD2 3.92Å; F271-L275 HydrophobicContact CE2-CG 4.13Å; F271-L275 HydrophobicContact CZ-CD1 3.82Å; F271-L275 HydrophobicContact CZ-CD2 3.69Å; F271-L275 HydrophobicContact CZ-CG 3.9Å; F271-L275 WeakPolarHBondContact O-CG 3.4Å; F271-L275 PolarHBondContact O-N 3.03Å; M272-L275 PolarHBondContact O-N 3.28Å; M272-L275 VanDerWaalsContact O-N 3.16Å; N273-L275 VanDerWaalsContact C-N 3.32Å; N273-L275 PolarHBondContact O-N 2.96Å; L275-L278 PolarHBondContact O-N 2.93Å; L275-K279 PolarHBondContact O-N 3.42Å; L275-M295 HydrophobicContact CB-CE 4.06Å; L275-M295 HydrophobicContact CD2-CE 3.52Å; L275-M295 HydrophobicContact CD2-SD 4.31Å; L275-M295 HydrophobicContact CG-CE 4.39Å; L275-L300 HydrophobicContact CB-CD1 3.71Å; L275-L300 HydrophobicContact CB-CD2 4.36Å; L275-L300 HydrophobicContact CB-CG 3.78Å; L275-L300 HydrophobicContact CD1-CD2 4.16Å; L275-L300 HydrophobicContact CD1-CG 4.04Å; L275-L300 HydrophobicContact CG-CG 4.49Å; L275-Q303 HydrophobicContact CD1-CB 4.32Å; L275-Q303 HydrophobicContact CD2-CB 4.4Å; L275-V304 HydrophobicContact CD1-CG2 3.61Å
276I81.3Confident74.2Confident9 Ų961.5 Ų61.55%0.04630%0.296CS..Hα-helixtrans-64.1-45175.2-69.3167.5000110.7I258 M272 N273 L274 L278 K279 Q280I258-I276 HydrophobicContact CG1-CD1 4.08Å; I258-I276 HydrophobicContact CG1-CG1 3.99Å; M272-I276 HydrophobicContact CG-CD1 3.91Å; M272-I276 HydrophobicContact CG-CG1 4.48Å; M272-I276 VanDerWaalsContact O-CG1 3.29Å; M272-I276 WeakPolarHBondContact O-CG1 3.48Å; M272-I276 PolarHBondContact O-N 3.39Å; M272-I276 HydrophobicContact SD-CD1 4.46Å; N273-I276 PolarHBondContact O-N 3.43Å; L274-I276 VanDerWaalsContact C-N 3.34Å; L274-I276 PolarHBondContact O-N 3.28Å; I276-L278 VanDerWaalsContact C-N 3.31Å; I276-L278 PolarHBondContact O-N 3.25Å; I276-K279 WeakPolarHBondContact O-CB 3.47Å; I276-K279 PolarHBondContact O-N 3.21Å; I276-K279 VanDerWaalsContact O-N 3.13Å; I276-Q280 HydrophobicContact CG2-CG 4.26Å; I276-Q280 WeakPolarHBondContact O-CB 3.28Å; I276-Q280 WeakPolarHBondContact O-CG 2.85Å; I276-Q280 PolarHBondContact O-N 2.79Å
277E79.1Confident73.6Confident59 Ų5964.4 Ų64.428%0.27632%0.317SS..Hα-helixtrans-61.3-40.4176-75178.9-169.500111.8N273 L274 K279 Q280 K281N273-E277 PolarHBondContact ND2-OE1 2.91Å; N273-E277 WeakPolarHBondContact O-CG 3.4Å; N273-E277 PolarHBondContact O-N 3.32Å; L274-E277 PolarHBondContact O-N 3.23Å; E277-K279 VanDerWaalsContact C-N 3.33Å; E277-K279 PolarHBondContact O-N 3.17Å; E277-Q280 PolarHBondContact O-N 3.36Å; E277-K281 WeakPolarHBondContact O-CB 3.2Å; E277-K281 VanDerWaalsContact O-CG 3.28Å; E277-K281 WeakPolarHBondContact O-CG 3.44Å; E277-K281 PolarHBondContact O-N 2.82Å
278L75.9Confident73.4Confident16 Ų1662.4 Ų62.48%0.08431%0.313CS..Hα-helixtrans-64.9-35.4174.7-72.1172000112.3R132 L274 L275 I276 V284 G294 M295R132-L278 HydrophobicContact CB-CD1 4.22Å; L274-L278 HydrophobicContact CG-CD1 4.31Å; L274-L278 VanDerWaalsContact O-CG 3.27Å; L274-L278 WeakPolarHBondContact O-CG 3.06Å; L274-L278 PolarHBondContact O-N 2.88Å; L275-L278 PolarHBondContact O-N 2.93Å; I276-L278 VanDerWaalsContact C-N 3.31Å; I276-L278 PolarHBondContact O-N 3.25Å; L278-V284 HydrophobicContact CD2-CG2 3.83Å; L278-G294 WeakPolarHBondContact O-CA 3.2Å; L278-M295 HydrophobicContact CB-CE 3.54Å; L278-M295 HydrophobicContact CD1-CE 3.78Å; L278-M295 HydrophobicContact CG-CE 4.33Å
279K77Confident73.3Confident72 Ų7261.6 Ų61.631%0.31333%0.325SS..Hα-helixtrans-66.7-46.1171.7173.5176.7179.3-67.10111.5L275 I276 E277 M295 L300L275-K279 PolarHBondContact O-N 3.42Å; I276-K279 WeakPolarHBondContact O-CB 3.47Å; I276-K279 PolarHBondContact O-N 3.21Å; I276-K279 VanDerWaalsContact O-N 3.13Å; E277-K279 VanDerWaalsContact C-N 3.33Å; E277-K279 PolarHBondContact O-N 3.17Å; K279-M295 WeakPolarHBondContact CG-O 3.16Å; K279-L300 HydrophobicContact CB-CD1 4.38Å; K279-L300 HydrophobicContact CD-CD1 4.4Å
280Q74.3Confident73.3Confident117 Ų11759.7 Ų59.755%0.54731%0.313SS..Hα-helixtrans-70.8-37.2-175.5-74176-9.200113.6I276 E277 G282I276-Q280 HydrophobicContact CG2-CG 4.26Å; I276-Q280 WeakPolarHBondContact O-CB 3.28Å; I276-Q280 WeakPolarHBondContact O-CG 2.85Å; I276-Q280 PolarHBondContact O-N 2.79Å; E277-Q280 PolarHBondContact O-N 3.36Å; Q280-G282 PolarHBondContact O-N 3.2Å; Q280-G282 VanDerWaalsContact O-N 3.14Å
281K67.8Low73Confident132 Ų13263 Ų6357%0.57433%0.334SS*.Hα-helixtrans-61-24.6-179.6-77.6174.9-177.3176.60112.4E277 R283 V284E277-K281 WeakPolarHBondContact O-CB 3.2Å; E277-K281 VanDerWaalsContact O-CG 3.28Å; E277-K281 WeakPolarHBondContact O-CG 3.44Å; E277-K281 PolarHBondContact O-N 2.82Å; K281-R283 PolarHBondContact O-N 3.09Å; K281-V284 HydrophobicContact CB-CG2 4.35Å
282G62.8Low72.4Confident38 Ų3862.7 Ų62.739%0.39233%0.332SS..SBendtrans67.2-31.8176.500000114.6Q280 E293 G294Q280-G282 PolarHBondContact O-N 3.2Å; Q280-G282 VanDerWaalsContact O-N 3.14Å; G282-E293 CarbonylContact O-C 3.57Å; G282-E293 WeakPolarHBondContact O-CA 2.98Å; G282-G294 PolarHBondContact O-N 3.49Å
283R67Low71.7Confident174 Ų17469.3 Ų69.366%0.65736%0.363SS*.EExtended strand (participates in β ladder)trans-144.7137.3170.1-69.1-178.8178.8159.40.8109.3K281 V291 I292K281-R283 PolarHBondContact O-N 3.09Å; R283-V291 HydrophobicContact CB-CG1 3.8Å; R283-V291 HydrophobicContact CG-CG1 4.02Å; R283-I292 CarbonylContact C-O 3.58Å; R283-I292 WeakPolarHBondContact CA-O 3.31Å
284V67.2Low71.1Confident30 Ų3069.6 Ų69.618%0.18237%0.37CS..EExtended strand (participates in β ladder)trans-119116.6174.1-179.80000107.5L278 K281 I292L278-V284 HydrophobicContact CD2-CG2 3.83Å; K281-V284 HydrophobicContact CB-CG2 4.35Å; V284-I292 PolarHBondContact N-O 3Å; V284-I292 PolarHBondContact O-N 3.43Å
285T69.6Low71.2Confident96 Ų9667.9 Ų67.959%0.58936%0.361SS*.EExtended strand (participates in β ladder)trans-82.2119.4169.4-49.50000108.1E290 V291T285-E290 WeakPolarHBondContact CA-O 3.42Å; T285-V291 HydrophobicContact CG2-CG2 4.42Å
286L66.6Low71.3Confident34 Ų3472 Ų7218%0.17838%0.383CS..  trans-75.3163.4173.9-68.5-172000111.2Q131 N288 G289 E290 I292Q131-L286 HydrophobicContact CB-CD1 4.26Å; Q131-L286 HydrophobicContact CG-CD1 4.42Å; L286-N288 WeakPolarHBondContact CB-OD1 3.33Å; L286-N288 PolarHBondContact O-N 3.26Å; L286-N288 VanDerWaalsContact O-N 3.08Å; L286-G289 PolarHBondContact O-N 2.97Å; L286-E290 HydrophobicContact CB-CB 4.48Å; L286-E290 HydrophobicContact CD1-CB 4.29Å; L286-E290 PolarHBondContact N-O 3.01Å; L286-I292 HydrophobicContact CD1-CD1 3.39Å; L286-I292 HydrophobicContact CD1-CG1 4.27Å; L286-I292 HydrophobicContact CD2-CD1 3.96Å; L286-I292 HydrophobicContact CG-CD1 3.61Å; L286-I292 HydrophobicContact CG-CG1 4.23Å
287D61.8Low71.6Confident180 Ų18074.1 Ų74.196%0.96339%0.393SS*.THydrogen-bonded Turntrans-59.3-21.9177.5-59-27.3000113.2G289D287-G289 VanDerWaalsContact C-N 3.33Å
288N67.4Low72.2Confident95 Ų9571.7 Ų71.751%0.50838%0.384SS..THydrogen-bonded Turntrans-88.36.1175.269.7-6.7000113.7L286 E290L286-N288 WeakPolarHBondContact CB-OD1 3.33Å; L286-N288 PolarHBondContact O-N 3.26Å; L286-N288 VanDerWaalsContact O-N 3.08Å; N288-E290 VanDerWaalsContact C-N 3.32Å; N288-E290 PolarHBondContact ND2-OE2 2.94Å; N288-E290 PolarHBondContact O-N 3.29Å; N288-E290 WeakPolarHBondContact OD1-CB 3.44Å; N288-E290 PolarHBondContact OD1-N 3.35Å
289G68.4Low72.8Confident51 Ų5172.4 Ų72.453%0.52639%0.387SS..SBendtrans81.5-2.9-178.100000115.4L286 D287 V291L286-G289 PolarHBondContact O-N 2.97Å; D287-G289 VanDerWaalsContact C-N 3.33Å; G289-V291 PolarHBondContact O-N 3.04Å
290E70.2Confident73.5Confident73 Ų7369 Ų6934%0.34137%0.372SS..  trans-70.2129.4176.3-72.3-179.9141.900110.7K127 T285 L286 N288K127-E290 IonicContact NZ-OE1 3.94Å; K127-E290 IonicContact NZ-OE2 2.75Å; T285-E290 WeakPolarHBondContact CA-O 3.42Å; L286-E290 HydrophobicContact CB-CB 4.48Å; L286-E290 HydrophobicContact CD1-CB 4.29Å; L286-E290 PolarHBondContact N-O 3.01Å; N288-E290 VanDerWaalsContact C-N 3.32Å; N288-E290 PolarHBondContact ND2-OE2 2.94Å; N288-E290 PolarHBondContact O-N 3.29Å; N288-E290 WeakPolarHBondContact OD1-CB 3.44Å; N288-E290 PolarHBondContact OD1-N 3.35Å
291V71.6Confident74.3Confident82 Ų8263.4 Ų63.450%0.49735%0.346SS..EExtended strand (participates in β ladder)trans-94.8124.3175.3-177.50000109.6R283 T285 G289R283-V291 HydrophobicContact CB-CG1 3.8Å; R283-V291 HydrophobicContact CG-CG1 4.02Å; T285-V291 HydrophobicContact CG2-CG2 4.42Å; G289-V291 PolarHBondContact O-N 3.04Å
292I67.7Low75.6Confident2 Ų257.1 Ų57.11%0.0132%0.319CS..EExtended strand (participates in β ladder)trans-115.3130-178.6-59.8-179.8000109.9D128 R132 R283 V284 L286D128-I292 HydrophobicContact CB-CD1 4.29Å; D128-I292 HydrophobicContact CB-CG2 4.19Å; R132-I292 HydrophobicContact CG-CG2 4.49Å; R283-I292 CarbonylContact C-O 3.58Å; R283-I292 WeakPolarHBondContact CA-O 3.31Å; V284-I292 PolarHBondContact N-O 3Å; V284-I292 PolarHBondContact O-N 3.43Å; L286-I292 HydrophobicContact CD1-CD1 3.39Å; L286-I292 HydrophobicContact CD1-CG1 4.27Å; L286-I292 HydrophobicContact CD2-CD1 3.96Å; L286-I292 HydrophobicContact CG-CD1 3.61Å; L286-I292 HydrophobicContact CG-CG1 4.23Å
293E69.3Low77.1Confident138 Ų13855.3 Ų55.365%0.64530%0.3SS*.EExtended strand (participates in β ladder)trans-65.3154.6177.2-63.3-173.3158.800113R132 G282R132-E293 PolarHBondContact NH1-O 3.03Å; R132-E293 PolarHBondContact NH2-O 3.15Å; G282-E293 CarbonylContact O-C 3.57Å; G282-E293 WeakPolarHBondContact O-CA 2.98Å
294G69.3Low78.2Confident20 Ų2047 Ų4721%0.20627%0.269CS..PPolyproline II helixtrans-63.3170.417600000113L278 G282L278-G294 WeakPolarHBondContact O-CA 3.2Å; G282-G294 PolarHBondContact O-N 3.49Å
295M79.1Confident79.4Confident8 Ų845.9 Ų45.94%0.03926%0.261CS..PPolyproline II helixtrans-89.2140.1177.6-73.5-178.5-61.600112.2M129 L275 L278 K279 E299 Q303M129-M295 HydrophobicContact CE-CG 4.31Å; M129-M295 HydrophobicContact CE-SD 3.91Å; M129-M295 HydrophobicContact SD-SD 4Å; L275-M295 HydrophobicContact CB-CE 4.06Å; L275-M295 HydrophobicContact CD2-CE 3.52Å; L275-M295 HydrophobicContact CD2-SD 4.31Å; L275-M295 HydrophobicContact CG-CE 4.39Å; L278-M295 HydrophobicContact CB-CE 3.54Å; L278-M295 HydrophobicContact CD1-CE 3.78Å; L278-M295 HydrophobicContact CG-CE 4.33Å; K279-M295 WeakPolarHBondContact CG-O 3.16Å; M295-E299 WeakPolarHBondContact CA-OE2 3.41Å; M295-E299 HydrophobicContact CB-CB 4.26Å; M295-E299 HydrophobicContact CG-CB 4.38Å; M295-Q303 HydrophobicContact SD-CG 4.46Å
296D85.2Confident80.5Confident87 Ų8742.6 Ų42.647%0.46524%0.24SC..PPolyproline II helixtrans-77.4170.4164.178.242.1000111.9G298 E299 L300D296-G298 VanDerWaalsContact C-N 3.3Å; D296-G298 PolarHBondContact O-N 3.23Å; D296-G298 VanDerWaalsContact OD1-CA 3.27Å; D296-G298 WeakPolarHBondContact OD1-CA 3.37Å; D296-G298 PolarHBondContact OD1-N 3.05Å; D296-E299 PolarHBondContact N-OE2 2.69Å; D296-E299 VanDerWaalsContact N-OE2 3.14Å; D296-E299 PolarHBondContact O-N 3.02Å; D296-E299 PolarHBondContact OD1-N 2.94Å; D296-L300 WeakPolarHBondContact O-CB 3.42Å; D296-L300 PolarHBondContact O-N 2.87Å
297I87.1Confident81.8Confident53 Ų5341.9 Ų41.927%0.27224%0.235SC..Hα-helixtrans-64.3-34.4-178-169.264.1000112.8V254 N255 I258 A301V254-I297 HydrophobicContact CG1-CD1 3.77Å; N255-I297 WeakPolarHBondContact OD1-CG1 3.43Å; I258-I297 HydrophobicContact CD1-CD1 3.44Å; I258-I297 VanDerWaalsContact CD1-CD1 3.44Å; I297-A301 VanDerWaalsContact O-CB 3.3Å; I297-A301 WeakPolarHBondContact O-CB 3.37Å; I297-A301 PolarHBondContact O-N 3.39Å
298G90.4Very high83.1Confident8 Ų833.3 Ų33.38%0.08219%0.19CC..Hα-helixtrans-70.8-42.2178.200000111.6D296 L300 A301 A302D296-G298 VanDerWaalsContact C-N 3.3Å; D296-G298 PolarHBondContact O-N 3.23Å; D296-G298 VanDerWaalsContact OD1-CA 3.27Å; D296-G298 WeakPolarHBondContact OD1-CA 3.37Å; D296-G298 PolarHBondContact OD1-N 3.05Å; G298-L300 VanDerWaalsContact C-N 3.34Å; G298-A301 PolarHBondContact O-N 3.32Å; G298-A302 VanDerWaalsContact O-CB 3.32Å; G298-A302 WeakPolarHBondContact O-CB 3.26Å; G298-A302 PolarHBondContact O-N 3.49Å
299E90.3Very high84.2Confident31 Ų3129.3 Ų29.315%0.14517%0.169CC..Hα-helixtrans-62.2-42.2173.9-70.4-176.8139.600111.5M295 D296 A302 Q303M295-E299 WeakPolarHBondContact CA-OE2 3.41Å; M295-E299 HydrophobicContact CB-CB 4.26Å; M295-E299 HydrophobicContact CG-CB 4.38Å; D296-E299 PolarHBondContact N-OE2 2.69Å; D296-E299 VanDerWaalsContact N-OE2 3.14Å; D296-E299 PolarHBondContact O-N 3.02Å; D296-E299 PolarHBondContact OD1-N 2.94Å; E299-A302 PolarHBondContact O-N 3.28Å; E299-Q303 WeakPolarHBondContact O-CG 3.41Å; E299-Q303 PolarHBondContact O-N 3.45Å; E299-Q303 PolarHBondContact O-NE2 2.8Å
300L90.1Very high85.3Confident0 Ų029.2 Ų29.20%016%0.163CC..Hα-helixtrans-63.6-48.3176.2-165.9152.2000110.6V254 I258 M272 L275 K279 D296 G298 A302 Q303 V304V254-L300 HydrophobicContact CG1-CD2 3.31Å; I258-L300 HydrophobicContact CD1-CD1 4.05Å; I258-L300 HydrophobicContact CD1-CD2 4.11Å; M272-L300 HydrophobicContact SD-CD2 3.92Å; L275-L300 HydrophobicContact CB-CD1 3.71Å; L275-L300 HydrophobicContact CB-CD2 4.36Å; L275-L300 HydrophobicContact CB-CG 3.78Å; L275-L300 HydrophobicContact CD1-CD2 4.16Å; L275-L300 HydrophobicContact CD1-CG 4.04Å; L275-L300 HydrophobicContact CG-CG 4.49Å; K279-L300 HydrophobicContact CB-CD1 4.38Å; K279-L300 HydrophobicContact CD-CD1 4.4Å; D296-L300 WeakPolarHBondContact O-CB 3.42Å; D296-L300 PolarHBondContact O-N 2.87Å; G298-L300 VanDerWaalsContact C-N 3.34Å; L300-A302 VanDerWaalsContact C-N 3.3Å; L300-A302 PolarHBondContact O-N 2.9Å; L300-Q303 PolarHBondContact O-N 3.14Å; L300-Q303 VanDerWaalsContact O-N 3.16Å; L300-V304 HydrophobicContact CD2-CG2 3.95Å; L300-V304 WeakPolarHBondContact O-CG2 3.21Å; L300-V304 PolarHBondContact O-N 3.34Å
301A92.3Very high86.1Confident0 Ų026 Ų260%015%0.15CC..Hα-helixtrans-62.2-37.8177.600000112.4L114 M251 V254 I297 G298 Q303 V304 F305L114-A301 HydrophobicContact CD2-CB 3.87Å; M251-A301 HydrophobicContact CE-CB 4.44Å; M251-A301 HydrophobicContact SD-CB 3.51Å; M251-A301 VanDerWaalsContact SD-CB 3.51Å; V254-A301 HydrophobicContact CB-CB 4.18Å; V254-A301 HydrophobicContact CG1-CB 4.2Å; V254-A301 HydrophobicContact CG2-CB 3.97Å; I297-A301 VanDerWaalsContact O-CB 3.3Å; I297-A301 WeakPolarHBondContact O-CB 3.37Å; I297-A301 PolarHBondContact O-N 3.39Å; G298-A301 PolarHBondContact O-N 3.32Å; A301-Q303 PolarHBondContact O-N 2.94Å; A301-V304 PolarHBondContact O-N 2.79Å; A301-F305 VanDerWaalsContact O-CB 3.23Å; A301-F305 WeakPolarHBondContact O-CB 3.47Å; A301-F305 PolarHBondContact O-N 2.84Å
302A94.3Very high86.9Confident0 Ų022.2 Ų22.20%013%0.127CC..Hα-helixtrans-62.1-41.3174.300000112.1P113 H117 G298 E299 L300 I306P113-A302 WeakPolarHBondContact O-CB 3.35Å; H117-A302 HydrophobicContact CB-CB 4.07Å; H117-A302 VanDerWaalsContact CB-O 3.24Å; H117-A302 WeakPolarHBondContact CB-O 3.36Å; G298-A302 VanDerWaalsContact O-CB 3.32Å; G298-A302 WeakPolarHBondContact O-CB 3.26Å; G298-A302 PolarHBondContact O-N 3.49Å; E299-A302 PolarHBondContact O-N 3.28Å; L300-A302 VanDerWaalsContact C-N 3.3Å; L300-A302 PolarHBondContact O-N 2.9Å; A302-I306 PolarHBondContact O-N 2.77Å
303Q93.3Very high87.9Confident0 Ų023 Ų230%013%0.13CC..Hα-helixtrans-67.3-47.6176-59.4-23.1-68.600111Q116 M129 L133 L275 M295 E299 L300 A301 F305 I306 F307Q116-Q303 PolarHBondContact O-NE2 3.44Å; Q116-Q303 VanDerWaalsContact O-NE2 3.12Å; M129-Q303 HydrophobicContact CE-CG 4.29Å; M129-Q303 HydrophobicContact SD-CG 3.84Å; L133-Q303 HydrophobicContact CD1-CG 4.28Å; L275-Q303 HydrophobicContact CD1-CB 4.32Å; L275-Q303 HydrophobicContact CD2-CB 4.4Å; M295-Q303 HydrophobicContact SD-CG 4.46Å; E299-Q303 WeakPolarHBondContact O-CG 3.41Å; E299-Q303 PolarHBondContact O-N 3.45Å; E299-Q303 PolarHBondContact O-NE2 2.8Å; L300-Q303 PolarHBondContact O-N 3.14Å; L300-Q303 VanDerWaalsContact O-N 3.16Å; A301-Q303 PolarHBondContact O-N 2.94Å; Q303-F305 VanDerWaalsContact C-N 3.27Å; Q303-F305 PolarHBondContact O-N 2.7Å; Q303-I306 VanDerWaalsContact O-CG2 3.26Å; Q303-I306 WeakPolarHBondContact O-CG2 3.12Å; Q303-I306 PolarHBondContact O-N 3.34Å; Q303-F307 HydrophobicContact CB-CD2 4.3Å; Q303-F307 HydrophobicContact CB-CE2 4.36Å; Q303-F307 WeakPolarHBondContact O-CD2 3.44Å; Q303-F307 PolarHBondContact O-N 3.16Å
304V90.9Very high89.1Confident0 Ų018.6 Ų18.60%011%0.113CC..Hα-helixtrans-53.7-47.7176.3164.50000111.1F192 V254 M272 L275 L300 A301 F307 Y308F192-V304 HydrophobicContact CD1-CG1 3.91Å; F192-V304 HydrophobicContact CD1-CG2 4.38Å; F192-V304 HydrophobicContact CE1-CB 4.04Å; F192-V304 HydrophobicContact CE1-CG1 3.55Å; F192-V304 HydrophobicContact CE1-CG2 4.1Å; F192-V304 HydrophobicContact CZ-CG1 4.12Å; F192-V304 WeakPolarHBondContact CZ-O 3.47Å; V254-V304 HydrophobicContact CG2-CB 3.93Å; V254-V304 HydrophobicContact CG2-CG1 3.75Å; V254-V304 HydrophobicContact CG2-CG2 4.07Å; M272-V304 HydrophobicContact CE-CG1 4.4Å; M272-V304 HydrophobicContact CE-CG2 3.7Å; M272-V304 HydrophobicContact SD-CG2 4.24Å; L275-V304 HydrophobicContact CD1-CG2 3.61Å; L300-V304 HydrophobicContact CD2-CG2 3.95Å; L300-V304 WeakPolarHBondContact O-CG2 3.21Å; L300-V304 PolarHBondContact O-N 3.34Å; A301-V304 PolarHBondContact O-N 2.79Å; V304-F307 PolarHBondContact O-N 3.15Å; V304-Y308 WeakPolarHBondContact O-CB 3.23Å; V304-Y308 PolarHBondContact O-N 3.13Å
305F92.8Very high90.4Very high5 Ų517.9 Ų17.92%0.02211%0.105CC..Hα-helixtrans-56.8-53.4176.6169.8-104.5000112.6L114 H117 V213 M242 V246 F250 A301 Q303 F307 Y308 V309L114-F305 HydrophobicContact CB-CD1 4.17Å; L114-F305 HydrophobicContact CB-CG 4.34Å; L114-F305 HydrophobicContact CD1-CD2 4.13Å; L114-F305 HydrophobicContact CD1-CG 4.23Å; L114-F305 HydrophobicContact CD2-CB 4.06Å; H117-F305 AromaticContact CD2-CD1 3.94Å; V213-F305 HydrophobicContact CG1-CE2 4.37Å; V213-F305 HydrophobicContact CG1-CZ 3.82Å; V213-F305 HydrophobicContact CG2-CE2 3.52Å; V213-F305 HydrophobicContact CG2-CZ 3.82Å; M242-F305 HydrophobicContact SD-CE1 3.9Å; M242-F305 HydrophobicContact SD-CE2 4.26Å; M242-F305 HydrophobicContact SD-CZ 3.48Å; M242-F305 WeakPolarHBondContact SD-CZ 3.39Å; V246-F305 HydrophobicContact CG1-CE2 4.02Å; F250-F305 HydrophobicContact CD1-CB 4.33Å; F250-F305 HydrophobicContact CD1-CD2 4.29Å; F250-F305 AromaticContact CD2-CD2 3.55Å; F250-F305 HydrophobicContact CD2-CD2 3.55Å; F250-F305 HydrophobicContact CD2-CE2 4.13Å; F250-F305 HydrophobicContact CE1-CD2 4.38Å; F250-F305 AromaticContact CE2-CD2 3.68Å; F250-F305 HydrophobicContact CE2-CD2 3.68Å; F250-F305 HydrophobicContact CE2-CE2 4.02Å; F250-F305 HydrophobicContact CG-CB 4.31Å; F250-F305 AromaticContact CG-CD2 3.91Å; F250-F305 HydrophobicContact CG-CD2 3.91Å; F250-F305 HydrophobicContact CZ-CD2 4.12Å; A301-F305 VanDerWaalsContact O-CB 3.23Å; A301-F305 WeakPolarHBondContact O-CB 3.47Å; A301-F305 PolarHBondContact O-N 2.84Å; Q303-F305 VanDerWaalsContact C-N 3.27Å; Q303-F305 PolarHBondContact O-N 2.7Å; F305-F307 PolarHBondContact O-N 2.78Å; F305-Y308 PolarHBondContact O-N 3.31Å; F305-V309 HydrophobicContact CD2-CG2 4.13Å; F305-V309 HydrophobicContact CE2-CG2 3.79Å; F305-V309 HydrophobicContact CZ-CG2 4.03Å; F305-V309 WeakPolarHBondContact O-CG2 3.36Å; F305-V309 PolarHBondContact O-N 3.46Å
306I93.1Very high91.1Very high27 Ų2717.5 Ų17.514%0.13810%0.103CC..Hα-helixtrans-67.3-36.6-176.3-168.756.6000112.5H117 F119 A302 Q303 Y308 V309 A310H117-I306 HydrophobicContact CB-CB 3.65Å; H117-I306 HydrophobicContact CB-CG1 4.29Å; H117-I306 HydrophobicContact CB-CG2 3.64Å; F119-I306 HydrophobicContact CB-CD1 4.31Å; F119-I306 HydrophobicContact CB-CG1 4.28Å; A302-I306 PolarHBondContact O-N 2.77Å; Q303-I306 VanDerWaalsContact O-CG2 3.26Å; Q303-I306 WeakPolarHBondContact O-CG2 3.12Å; Q303-I306 PolarHBondContact O-N 3.34Å; I306-Y308 VanDerWaalsContact C-N 3.33Å; I306-V309 PolarHBondContact O-N 3.43Å; I306-A310 WeakPolarHBondContact O-CB 3.45Å; I306-A310 PolarHBondContact O-N 3.46Å
307F92.3Very high91.7Very high19 Ų1913.4 Ų13.48%0.0838%0.081CC..Hα-helixtrans-71.5-31.8179.9-79.9-69.8000112.1L133 F137 F271 Q303 V304 F305 G311 I452L133-F307 HydrophobicContact CD1-CE2 3.8Å; L133-F307 HydrophobicContact CD1-CZ 4.02Å; L133-F307 HydrophobicContact CD2-CE2 4.22Å; F137-F307 HydrophobicContact CE1-CE1 4.26Å; F137-F307 HydrophobicContact CE2-CD1 4.3Å; F137-F307 AromaticContact CE2-CE1 3.41Å; F137-F307 HydrophobicContact CE2-CE1 3.41Å; F137-F307 VanDerWaalsContact CE2-CE1 3.41Å; F137-F307 AromaticContact CE2-CZ 3.67Å; F137-F307 HydrophobicContact CE2-CZ 3.67Å; F137-F307 AromaticContact CZ-CD1 3.66Å; F137-F307 HydrophobicContact CZ-CD1 3.66Å; F137-F307 AromaticContact CZ-CE1 3.18Å; F137-F307 HydrophobicContact CZ-CE1 3.18Å; F137-F307 AromaticContact CZ-CZ 3.89Å; F137-F307 HydrophobicContact CZ-CZ 3.89Å; F271-F307 HydrophobicContact CD1-CD2 4.38Å; F271-F307 HydrophobicContact CE1-CB 4.05Å; F271-F307 AromaticContact CE1-CD2 3.27Å; F271-F307 HydrophobicContact CE1-CD2 3.27Å; F271-F307 AromaticContact CE1-CE2 3.91Å; F271-F307 HydrophobicContact CE1-CE2 3.91Å; F271-F307 AromaticContact CE1-CG 3.8Å; F271-F307 HydrophobicContact CE1-CG 3.8Å; F271-F307 HydrophobicContact CE2-CD2 4.3Å; F271-F307 HydrophobicContact CE2-CE2 4.16Å; F271-F307 AromaticContact CZ-CD2 3.22Å; F271-F307 HydrophobicContact CZ-CD2 3.22Å; F271-F307 AromaticContact CZ-CE2 3.31Å; F271-F307 HydrophobicContact CZ-CE2 3.31Å; F271-F307 HydrophobicContact CZ-CG 4.01Å; F271-F307 HydrophobicContact CZ-CZ 4.15Å; Q303-F307 HydrophobicContact CB-CD2 4.3Å; Q303-F307 HydrophobicContact CB-CE2 4.36Å; Q303-F307 WeakPolarHBondContact O-CD2 3.44Å; Q303-F307 PolarHBondContact O-N 3.16Å; V304-F307 PolarHBondContact O-N 3.15Å; F305-F307 PolarHBondContact O-N 2.78Å; F307-G311 WeakPolarHBondContact O-CA 3.32Å; F307-G311 PolarHBondContact O-N 2.88Å; F307-I452 HydrophobicContact CE1-CG2 3.64Å; F307-I452 HydrophobicContact CZ-CG2 3.93Å
308Y90.9Very high92.2Very high0 Ų011.6 Ų11.60%07%0.072CC..Hα-helixtrans-62.3-60169.3172.9-120.8000110.5T184 I187 F192 F206 R207 G210 F250 V304 F305 I306 A310 G311 F312T184-Y308 HydrophobicContact CG2-CE2 4.25Å; I187-Y308 HydrophobicContact CG2-CD2 3.7Å; I187-Y308 HydrophobicContact CG2-CE2 4.04Å; F192-Y308 HydrophobicContact CE2-CD2 4.17Å; F192-Y308 HydrophobicContact CE2-CG 4.33Å; F206-Y308 HydrophobicContact CD1-CD2 4.16Å; F206-Y308 AromaticContact CD1-CE2 3.49Å; F206-Y308 HydrophobicContact CD1-CE2 3.49Å; F206-Y308 VanDerWaalsContact CD1-CE2 3.49Å; F206-Y308 AromaticContact CD1-CZ 3.69Å; F206-Y308 AromaticContact CE1-CD2 3.23Å; F206-Y308 HydrophobicContact CE1-CD2 3.23Å; F206-Y308 HydrophobicContact CE1-CE1 4.36Å; F206-Y308 AromaticContact CE1-CE2 2.99Å; F206-Y308 HydrophobicContact CE1-CE2 2.99Å; F206-Y308 HydrophobicContact CE1-CG 4.07Å; F206-Y308 AromaticContact CE1-CZ 3.62Å; F206-Y308 HydrophobicContact CE2-CD2 4.46Å; F206-Y308 HydrophobicContact CG-CE2 4.49Å; F206-Y308 HydrophobicContact CZ-CD1 4.36Å; F206-Y308 AromaticContact CZ-CD2 3.39Å; F206-Y308 HydrophobicContact CZ-CD2 3.39Å; F206-Y308 HydrophobicContact CZ-CE1 4.46Å; F206-Y308 AromaticContact CZ-CE2 3.63Å; F206-Y308 HydrophobicContact CZ-CE2 3.63Å; F206-Y308 AromaticContact CZ-CG 3.81Å; F206-Y308 HydrophobicContact CZ-CG 3.81Å; F206-Y308 PolarHBondContact O-OH 3Å; R207-Y308 WeakPolarHBondContact CA-OH 3.42Å; G210-Y308 VanDerWaalsContact CA-CE1 3.43Å; F250-Y308 AromaticContact CE1-CD1 3.62Å; F250-Y308 HydrophobicContact CE1-CD1 3.62Å; F250-Y308 HydrophobicContact CE1-CE1 4.28Å; F250-Y308 HydrophobicContact CE1-CG 4.21Å; F250-Y308 AromaticContact CZ-CD1 3.35Å; F250-Y308 HydrophobicContact CZ-CD1 3.35Å; F250-Y308 AromaticContact CZ-CE1 3.7Å; F250-Y308 HydrophobicContact CZ-CE1 3.7Å; F250-Y308 HydrophobicContact CZ-CG 4.35Å; V304-Y308 WeakPolarHBondContact O-CB 3.23Å; V304-Y308 PolarHBondContact O-N 3.13Å; F305-Y308 PolarHBondContact O-N 3.31Å; I306-Y308 VanDerWaalsContact C-N 3.33Å; Y308-A310 PolarHBondContact O-N 2.9Å; Y308-G311 PolarHBondContact O-N 3.2Å; Y308-F312 HydrophobicContact CD1-CD1 4.28Å; Y308-F312 HydrophobicContact CD1-CE1 4.2Å; Y308-F312 HydrophobicContact CD2-CD1 4.02Å; Y308-F312 AromaticContact CE1-CD1 3.96Å; Y308-F312 HydrophobicContact CE1-CD1 3.96Å; Y308-F312 AromaticContact CE1-CE1 3.74Å; Y308-F312 HydrophobicContact CE1-CE1 3.74Å; Y308-F312 HydrophobicContact CE2-CB 4.49Å; Y308-F312 AromaticContact CE2-CD1 3.58Å; Y308-F312 HydrophobicContact CE2-CD1 3.58Å; Y308-F312 HydrophobicContact CE2-CE1 4.2Å; Y308-F312 HydrophobicContact CE2-CG 4.28Å; Y308-F312 HydrophobicContact CG-CD1 4.34Å; Y308-F312 AromaticContact CZ-CD1 3.57Å; Y308-F312 AromaticContact CZ-CE1 3.71Å; Y308-F312 VanDerWaalsContact O-CD1 3.24Å; Y308-F312 WeakPolarHBondContact O-CD1 3.41Å; Y308-F312 PolarHBondContact O-N 2.91Å; Y308-F312 VanDerWaalsContact O-N 3.15Å
309V90.1Very high92.6Very high11 Ų1111.2 Ų11.27%0.0677%0.068CC..Hα-helixtrans-57.7-46.2-175.2172.80000112V213 F214 F305 I306 G311V213-V309 HydrophobicContact CB-CG2 4.4Å; V213-V309 HydrophobicContact CG1-CG1 4.11Å; V213-V309 HydrophobicContact CG1-CG2 4.2Å; V213-V309 HydrophobicContact CG2-CG2 4Å; F214-V309 HydrophobicContact CE1-CG1 4.18Å; F214-V309 HydrophobicContact CE2-CG1 3.67Å; F214-V309 HydrophobicContact CZ-CG1 3.31Å; F305-V309 HydrophobicContact CD2-CG2 4.13Å; F305-V309 HydrophobicContact CE2-CG2 3.79Å; F305-V309 HydrophobicContact CZ-CG2 4.03Å; F305-V309 WeakPolarHBondContact O-CG2 3.36Å; F305-V309 PolarHBondContact O-N 3.46Å; I306-V309 PolarHBondContact O-N 3.43Å; V309-G311 VanDerWaalsContact C-N 3.31Å; V309-G311 PolarHBondContact O-N 3.13Å
310A91.4Very high92.9Very high49 Ų499.8 Ų9.841%0.4056%0.062SC..Hα-helixtrans-73.4-22.5177.700000113.1I306 Y308 T314I306-A310 WeakPolarHBondContact O-CB 3.45Å; I306-A310 PolarHBondContact O-N 3.46Å; Y308-A310 PolarHBondContact O-N 2.9Å; A310-T314 PolarHBondContact O-OG1 3.29Å
311G87.3Confident93.4Very high7 Ų79.9 Ų9.97%0.0726%0.062CC..Hα-helixtrans-79.7-37.1-177.100000113.6F307 Y308 V309 S315 Q460F307-G311 WeakPolarHBondContact O-CA 3.32Å; F307-G311 PolarHBondContact O-N 2.88Å; Y308-G311 PolarHBondContact O-N 3.2Å; V309-G311 VanDerWaalsContact C-N 3.31Å; V309-G311 PolarHBondContact O-N 3.13Å; G311-S315 PolarHBondContact O-OG 2.97Å; G311-Q460 PolarHBondContact O-NE2 3.37Å
312F86.9Confident93.7Very high2 Ų29.9 Ų9.91%0.0096%0.062CC..Hα-helixtrans-91.9-52.4-17587.3-98.8000113.1T183 I187 F214 Y308 T314 S316T183-F312 PolarHBondContact OG1-O 3.34Å; T183-F312 VanDerWaalsContact OG1-O 3.08Å; I187-F312 HydrophobicContact CG2-CB 4.34Å; F214-F312 HydrophobicContact CD2-CZ 4.33Å; F214-F312 HydrophobicContact CE2-CE1 4.31Å; F214-F312 HydrophobicContact CE2-CE2 4.49Å; F214-F312 AromaticContact CE2-CZ 3.76Å; F214-F312 HydrophobicContact CE2-CZ 3.76Å; Y308-F312 HydrophobicContact CD1-CD1 4.28Å; Y308-F312 HydrophobicContact CD1-CE1 4.2Å; Y308-F312 HydrophobicContact CD2-CD1 4.02Å; Y308-F312 AromaticContact CE1-CD1 3.96Å; Y308-F312 HydrophobicContact CE1-CD1 3.96Å; Y308-F312 AromaticContact CE1-CE1 3.74Å; Y308-F312 HydrophobicContact CE1-CE1 3.74Å; Y308-F312 HydrophobicContact CE2-CB 4.49Å; Y308-F312 AromaticContact CE2-CD1 3.58Å; Y308-F312 HydrophobicContact CE2-CD1 3.58Å; Y308-F312 HydrophobicContact CE2-CE1 4.2Å; Y308-F312 HydrophobicContact CE2-CG 4.28Å; Y308-F312 HydrophobicContact CG-CD1 4.34Å; Y308-F312 AromaticContact CZ-CD1 3.57Å; Y308-F312 AromaticContact CZ-CE1 3.71Å; Y308-F312 VanDerWaalsContact O-CD1 3.24Å; Y308-F312 WeakPolarHBondContact O-CD1 3.41Å; Y308-F312 PolarHBondContact O-N 2.91Å; Y308-F312 VanDerWaalsContact O-N 3.15Å; F312-T314 PolarHBondContact O-N 3.05Å; F312-S316 VanDerWaalsContact O-CB 3.27Å; F312-S316 WeakPolarHBondContact O-CB 3.43Å; F312-S316 PolarHBondContact O-N 3.04Å; F312-S316 VanDerWaalsContact O-N 3.09Å; F312-S316 PolarHBondContact O-OG 2.89Å
313E90.2Very high93.9Very high19 Ų199.9 Ų9.99%0.0896%0.062CC..Hα-helixtrans-70.3-40.8-167.4-176.264.2-164.400112.3K176 F214 S316 S317 V492K176-E313 IonicContact NZ-OE1 2.99Å; F214-E313 HydrophobicContact CD2-CG 4.35Å; F214-E313 HydrophobicContact CE1-CG 4.24Å; F214-E313 HydrophobicContact CE2-CB 3.67Å; F214-E313 HydrophobicContact CE2-CG 3.82Å; F214-E313 HydrophobicContact CZ-CB 3.63Å; F214-E313 HydrophobicContact CZ-CG 3.74Å; E313-S316 PolarHBondContact O-OG 3.5Å; E313-S317 WeakPolarHBondContact O-CB 3.48Å; E313-S317 PolarHBondContact O-N 3.13Å; E313-S317 VanDerWaalsContact O-N 3.1Å; E313-S317 PolarHBondContact O-OG 3.33Å; E313-V492 HydrophobicContact CG-CG2 4.11Å
314T93.8Very high94.1Very high45 Ų4510.2 Ų10.228%0.2766%0.063SC..Hα-helixtrans-74.6-43.4-17659.30000112.2A310 F312 T318 L375A310-T314 PolarHBondContact O-OG1 3.29Å; F312-T314 PolarHBondContact O-N 3.05Å; T314-T318 WeakPolarHBondContact O-CB 3.28Å; T314-T318 PolarHBondContact O-N 2.67Å; T314-T318 PolarHBondContact O-OG1 3.14Å; T314-L375 HydrophobicContact CG2-CD1 4.25Å; T314-L375 WeakPolarHBondContact O-CD1 3.05Å
315S95.7Very high94.5Very high5 Ų511.1 Ų11.14%0.0357%0.068CC..Hα-helixtrans-66.3-41.6179.2-570000111.1G311 T318 M319 Q460G311-S315 PolarHBondContact O-OG 2.97Å; S315-T318 PolarHBondContact O-N 2.78Å; S315-M319 PolarHBondContact O-N 3.41Å; S315-Q460 PolarHBondContact OG-NE2 2.91Å
316S95.6Very high94.8Very high0 Ų010.9 Ų10.90%07%0.067CC..Hα-helixtrans-64.3-45.6177.654.50000112.1M179 A180 F312 E313 T318 M319 S320M179-S316 VanDerWaalsContact C-CB 3.4Å; M179-S316 WeakPolarHBondContact O-CB 3.29Å; A180-S316 VanDerWaalsContact CA-CB 3.49Å; F312-S316 VanDerWaalsContact O-CB 3.27Å; F312-S316 WeakPolarHBondContact O-CB 3.43Å; F312-S316 PolarHBondContact O-N 3.04Å; F312-S316 VanDerWaalsContact O-N 3.09Å; F312-S316 PolarHBondContact O-OG 2.89Å; E313-S316 PolarHBondContact O-OG 3.5Å; S316-T318 VanDerWaalsContact C-N 3.33Å; S316-T318 PolarHBondContact O-N 3.49Å; S316-M319 PolarHBondContact O-N 3.34Å; S316-S320 WeakPolarHBondContact O-CB 3.3Å; S316-S320 PolarHBondContact O-N 2.93Å; S316-S320 PolarHBondContact O-OG 3.3Å
317S96.1Very high95.1Very high1 Ų19.8 Ų9.81%0.0076%0.062CC..Hα-helixtrans-60.2-42.5175.5-62.30000111.8E313 S320 Y321E313-S317 WeakPolarHBondContact O-CB 3.48Å; E313-S317 PolarHBondContact O-N 3.13Å; E313-S317 VanDerWaalsContact O-N 3.1Å; E313-S317 PolarHBondContact O-OG 3.33Å; S317-S320 PolarHBondContact O-N 3.31Å; S317-Y321 WeakPolarHBondContact O-CD2 3.38Å; S317-Y321 PolarHBondContact O-N 3.48Å
318T98Very high95.3Very high14 Ų1412.1 Ų12.19%0.0867%0.073CC..Hα-helixtrans-60.2-49178.3-56.90000111.7T314 S315 S316 S320 Y321 C322 I366 L370 L375T314-T318 WeakPolarHBondContact O-CB 3.28Å; T314-T318 PolarHBondContact O-N 2.67Å; T314-T318 PolarHBondContact O-OG1 3.14Å; S315-T318 PolarHBondContact O-N 2.78Å; S316-T318 VanDerWaalsContact C-N 3.33Å; S316-T318 PolarHBondContact O-N 3.49Å; T318-S320 VanDerWaalsContact C-N 3.31Å; T318-S320 PolarHBondContact O-N 3.09Å; T318-Y321 PolarHBondContact O-N 3.01Å; T318-C322 WeakPolarHBondContact O-CB 3.32Å; T318-C322 PolarHBondContact O-N 2.58Å; T318-I366 HydrophobicContact CG2-CG2 4.48Å; T318-L370 HydrophobicContact CG2-CD2 3.7Å; T318-L370 HydrophobicContact CG2-CG 3.98Å; T318-L375 WeakPolarHBondContact OG1-CD1 3.38Å
319M98.6Very high95.7Very high0 Ų014.2 Ų14.20%08%0.084CC..Hα-helixtrans-65-37177.4-67.6-176.6-74.300112M179 F182 T183 S315 S316 C322 L323 A461 L465M179-M319 HydrophobicContact CB-CE 4.33Å; M179-M319 HydrophobicContact CG-CB 3.94Å; M179-M319 HydrophobicContact SD-CB 3.45Å; M179-M319 WeakPolarHBondContact SD-CB 3.47Å; M179-M319 HydrophobicContact SD-CE 3.78Å; M179-M319 HydrophobicContact SD-CG 4.22Å; M179-M319 HydrophobicContact SD-SD 3.74Å; F182-M319 HydrophobicContact CD1-CE 3.73Å; F182-M319 HydrophobicContact CD1-SD 4.24Å; F182-M319 HydrophobicContact CE1-CE 4.07Å; F182-M319 HydrophobicContact CE1-SD 4.17Å; T183-M319 HydrophobicContact CG2-CE 3.26Å; S315-M319 PolarHBondContact O-N 3.41Å; S316-M319 PolarHBondContact O-N 3.34Å; M319-C322 WeakPolarHBondContact O-CB 3.28Å; M319-C322 PolarHBondContact O-N 3.48Å; M319-L323 VanDerWaalsContact O-CG 3.28Å; M319-L323 WeakPolarHBondContact O-CG 3.34Å; M319-L323 PolarHBondContact O-N 3.3Å; M319-A461 HydrophobicContact CG-CB 3.99Å; M319-A461 HydrophobicContact SD-CB 4.49Å; M319-L465 HydrophobicContact CB-CD2 4.21Å; M319-L465 HydrophobicContact CB-CG 4.37Å; M319-L465 HydrophobicContact CG-CD1 4.29Å; M319-L465 HydrophobicContact CG-CD2 4.38Å; M319-L465 HydrophobicContact CG-CG 3.99Å
320S98.4Very high96.1Very high1 Ų116.1 Ų16.11%0.0079%0.092CC..Hα-helixtrans-65.3-43.8179.5-51.20000111.9K176 M179 S316 S317 T318 L323 Y324K176-S320 WeakPolarHBondContact CA-OG 3.17Å; M179-S320 WeakPolarHBondContact CG-OG 3.42Å; S316-S320 WeakPolarHBondContact O-CB 3.3Å; S316-S320 PolarHBondContact O-N 2.93Å; S316-S320 PolarHBondContact O-OG 3.3Å; S317-S320 PolarHBondContact O-N 3.31Å; T318-S320 VanDerWaalsContact C-N 3.31Å; T318-S320 PolarHBondContact O-N 3.09Å; S320-L323 PolarHBondContact O-N 3.28Å; S320-Y324 WeakPolarHBondContact O-CB 3.39Å; S320-Y324 PolarHBondContact O-N 3.36Å
321Y98.6Very high96.4Very high2 Ų219.1 Ų19.11%0.00810%0.101CC..Hα-helixtrans-67.8-37174.8-64.9-47.8000112.4S317 T318 Y324 E325 Y373 L375 L484 Y486 L493 G494 T495 I499S317-Y321 WeakPolarHBondContact O-CD2 3.38Å; S317-Y321 PolarHBondContact O-N 3.48Å; T318-Y321 PolarHBondContact O-N 3.01Å; Y321-Y324 WeakPolarHBondContact O-CB 3.46Å; Y321-Y324 PolarHBondContact O-N 2.94Å; Y321-E325 PolarHBondContact O-N 2.86Å; Y321-Y373 AromaticContact CD1-CD1 3.5Å; Y321-Y373 HydrophobicContact CD1-CD1 3.5Å; Y321-Y373 AromaticContact CD1-CE1 3.66Å; Y321-Y373 HydrophobicContact CD1-CE1 3.66Å; Y321-Y373 HydrophobicContact CD1-CG 4.1Å; Y321-Y373 AromaticContact CD2-CD1 3.83Å; Y321-Y373 HydrophobicContact CD2-CD1 3.83Å; Y321-Y373 AromaticContact CD2-CG 3.8Å; Y321-Y373 HydrophobicContact CD2-CG 3.8Å; Y321-Y373 AromaticContact CE1-CD1 3.91Å; Y321-Y373 HydrophobicContact CE1-CD1 3.91Å; Y321-Y373 HydrophobicContact CE1-CE1 4.17Å; Y321-Y373 HydrophobicContact CE2-CD1 4.2Å; Y321-Y373 HydrophobicContact CE2-CG 4.49Å; Y321-Y373 AromaticContact CG-CD1 3.48Å; Y321-Y373 HydrophobicContact CG-CD1 3.48Å; Y321-Y373 VanDerWaalsContact CG-CD1 3.48Å; Y321-Y373 HydrophobicContact CG-CD2 4.19Å; Y321-Y373 HydrophobicContact CG-CE1 4.01Å; Y321-Y373 AromaticContact CG-CG 3.58Å; Y321-Y373 HydrophobicContact CG-CG 3.58Å; Y321-L375 HydrophobicContact CD2-CD2 4.01Å; Y321-L375 HydrophobicContact CE2-CD2 3.58Å; Y321-L484 HydrophobicContact CD1-CD1 3.84Å; Y321-L484 HydrophobicContact CE1-CD1 3.83Å; Y321-Y486 HydrophobicContact CE1-CE1 4.23Å; Y321-L493 PolarHBondContact OH-O 2.93Å; Y321-G494 WeakPolarHBondContact OH-CA 3.41Å; Y321-T495 HydrophobicContact CE1-CG2 3.83Å; Y321-I499 HydrophobicContact CD1-CD1 3.79Å; Y321-I499 HydrophobicContact CE1-CD1 3.91Å
322C98.8Very high97Very high0 Ų019.4 Ų19.40%010%0.101CC..Hα-helixtrans-60.2-48.8174-179.20000111T318 M319 Y324 E325 L326 V365 T369 L465T318-C322 WeakPolarHBondContact O-CB 3.32Å; T318-C322 PolarHBondContact O-N 2.58Å; M319-C322 WeakPolarHBondContact O-CB 3.28Å; M319-C322 PolarHBondContact O-N 3.48Å; C322-Y324 VanDerWaalsContact C-N 3.31Å; C322-Y324 PolarHBondContact O-N 2.98Å; C322-E325 PolarHBondContact O-N 2.84Å; C322-L326 WeakPolarHBondContact O-CB 3.49Å; C322-L326 VanDerWaalsContact O-CG 3.27Å; C322-L326 WeakPolarHBondContact O-CG 3.31Å; C322-L326 PolarHBondContact O-N 2.87Å; C322-V365 VanDerWaalsContact SG-CG1 3.59Å; C322-T369 HydrophobicContact CB-CG2 3.92Å; C322-L465 HydrophobicContact CB-CD1 4.08Å; C322-L465 HydrophobicContact CB-CD2 4.01Å
323L98.8Very high97.6Very high1 Ų119.3 Ų19.31%0.00510%0.101CC..Hα-helixtrans-64.3-35.5177.5-67.7168.1000112.3I175 M179 M319 S320 L326 A327 L465 I468 I469 V474 L501I175-L323 HydrophobicContact CG2-CB 4.23Å; I175-L323 HydrophobicContact CG2-CD1 3.5Å; I175-L323 VanDerWaalsContact CG2-CD1 3.5Å; M179-L323 HydrophobicContact SD-CD1 4.19Å; M319-L323 VanDerWaalsContact O-CG 3.28Å; M319-L323 WeakPolarHBondContact O-CG 3.34Å; M319-L323 PolarHBondContact O-N 3.3Å; S320-L323 PolarHBondContact O-N 3.28Å; L323-L326 PolarHBondContact O-N 2.98Å; L323-A327 VanDerWaalsContact O-CB 3.25Å; L323-A327 WeakPolarHBondContact O-CB 3.45Å; L323-A327 PolarHBondContact O-N 3.14Å; L323-L465 HydrophobicContact CD1-CD2 4.42Å; L323-L465 HydrophobicContact CD2-CD2 3.87Å; L323-L465 HydrophobicContact CG-CD2 3.8Å; L323-I468 HydrophobicContact CD1-CD1 3.7Å; L323-I468 HydrophobicContact CD2-CD1 4.36Å; L323-I468 HydrophobicContact CD2-CG2 3.99Å; L323-I469 HydrophobicContact CD2-CD1 3.91Å; L323-V474 HydrophobicContact CD2-CG1 4.31Å; L323-V474 HydrophobicContact CD2-CG2 4.16Å; L323-L501 HydrophobicContact CB-CD1 3.96Å; L323-L501 WeakPolarHBondContact O-CD1 3.44Å
324Y98.8Very high98Very high6 Ų620.9 Ų20.92%0.02411%0.11CC..Hα-helixtrans-61.5-43.9173.5171.6-97.8000112.3S320 Y321 C322 Q328 Y373 T480 E481 I482 L484 I499S320-Y324 WeakPolarHBondContact O-CB 3.39Å; S320-Y324 PolarHBondContact O-N 3.36Å; Y321-Y324 WeakPolarHBondContact O-CB 3.46Å; Y321-Y324 PolarHBondContact O-N 2.94Å; C322-Y324 VanDerWaalsContact C-N 3.31Å; C322-Y324 PolarHBondContact O-N 2.98Å; Y324-Q328 PolarHBondContact O-N 3.15Å; Y324-Q328 PolarHBondContact O-NE2 2.77Å; Y324-Y373 WeakPolarHBondContact CD1-OH 3.24Å; Y324-Y373 VanDerWaalsContact CE1-OH 3.25Å; Y324-Y373 WeakPolarHBondContact CE1-OH 3.34Å; Y324-T480 HydrophobicContact CD2-CG2 4.28Å; Y324-T480 HydrophobicContact CE2-CG2 4.06Å; Y324-E481 WeakPolarHBondContact CE2-O 3.26Å; Y324-E481 PolarHBondContact OH-O 2.73Å; Y324-I482 HydrophobicContact CE2-CG1 4.19Å; Y324-L484 HydrophobicContact CD1-CD1 3.72Å; Y324-L484 HydrophobicContact CD1-CG 4.29Å; Y324-L484 HydrophobicContact CD2-CD1 4.11Å; Y324-L484 HydrophobicContact CD2-CD2 4.07Å; Y324-L484 HydrophobicContact CD2-CG 4.13Å; Y324-L484 HydrophobicContact CE1-CD1 3.7Å; Y324-L484 HydrophobicContact CE1-CG 3.86Å; Y324-L484 HydrophobicContact CE2-CD1 4.09Å; Y324-L484 HydrophobicContact CE2-CD2 3.78Å; Y324-L484 HydrophobicContact CE2-CG 3.67Å; Y324-L484 HydrophobicContact CG-CD1 3.94Å; Y324-L484 HydrophobicContact CG-CG 4.43Å; Y324-I499 HydrophobicContact CD2-CG2 4.13Å
325E98.8Very high98.2Very high19 Ų1924.4 Ų24.49%0.08912%0.118CC..Hα-helixtrans-68-45175.5-71.7-60.6160.100112Y321 C322 A327 Q328 N329 Y373 F423Y321-E325 PolarHBondContact O-N 2.86Å; C322-E325 PolarHBondContact O-N 2.84Å; E325-A327 VanDerWaalsContact C-N 3.25Å; E325-A327 PolarHBondContact O-N 3.42Å; E325-Q328 PolarHBondContact O-N 3.5Å; E325-Q328 VanDerWaalsContact O-N 3.12Å; E325-N329 PolarHBondContact O-N 2.81Å; E325-N329 PolarHBondContact O-ND2 3.47Å; E325-N329 PolarHBondContact OE2-ND2 2.85Å; E325-Y373 HydrophobicContact CG-CE2 3.66Å; E325-Y373 VanDerWaalsContact OE1-CE2 3.24Å; E325-Y373 WeakPolarHBondContact OE1-CE2 3.23Å; E325-Y373 VanDerWaalsContact OE1-CZ 3.23Å; E325-Y373 PolarHBondContact OE1-OH 2.96Å; E325-F423 HydrophobicContact CB-CD1 3.94Å; E325-F423 HydrophobicContact CB-CD2 3.98Å; E325-F423 HydrophobicContact CB-CE1 3.86Å; E325-F423 HydrophobicContact CB-CE2 3.89Å; E325-F423 HydrophobicContact CB-CG 3.99Å; E325-F423 HydrophobicContact CB-CZ 3.83Å; E325-F423 HydrophobicContact CG-CD1 4.48Å; E325-F423 HydrophobicContact CG-CD2 3.71Å; E325-F423 HydrophobicContact CG-CE2 3.88Å; E325-F423 HydrophobicContact CG-CG 4.03Å; E325-F423 HydrophobicContact CG-CZ 4.34Å
326L98.8Very high98.3Very high0 Ų024.2 Ų24.20%012%0.117CC..Hα-helixtrans-62.7-32.7177.6-68.4176000112.5C322 L323 Q328 N329 Q330 I332 Q333 L336 V365 I469 V474C322-L326 WeakPolarHBondContact O-CB 3.49Å; C322-L326 VanDerWaalsContact O-CG 3.27Å; C322-L326 WeakPolarHBondContact O-CG 3.31Å; C322-L326 PolarHBondContact O-N 2.87Å; L323-L326 PolarHBondContact O-N 2.98Å; L326-Q328 VanDerWaalsContact C-N 3.28Å; L326-Q328 PolarHBondContact O-N 2.95Å; L326-N329 CarbonylContact O-C 3.54Å; L326-N329 PolarHBondContact O-N 2.86Å; L326-Q330 PolarHBondContact O-NE2 2.85Å; L326-I332 HydrophobicContact CD2-CB 4.44Å; L326-I332 HydrophobicContact CD2-CG2 3.75Å; L326-Q333 HydrophobicContact CB-CB 4.24Å; L326-Q333 HydrophobicContact CB-CG 4.2Å; L326-Q333 HydrophobicContact CD2-CB 4.25Å; L326-Q333 PolarHBondContact O-NE2 3.39Å; L326-L336 HydrophobicContact CD1-CD2 3.76Å; L326-L336 HydrophobicContact CD2-CD2 4.22Å; L326-V365 HydrophobicContact CD1-CG1 4.37Å; L326-V365 HydrophobicContact CD2-CG1 4Å; L326-V365 HydrophobicContact CG-CG1 4.35Å; L326-I469 HydrophobicContact CD1-CD1 3.83Å; L326-I469 HydrophobicContact CD1-CG1 4.1Å; L326-V474 HydrophobicContact CB-CG2 4.43Å
327A98.6Very high98.5Very high4 Ų424.7 Ų24.73%0.03312%0.119CC..Hα-helixtrans-66.4-30.5176.500000113L323 E325 Q330 V474 V476 L501L323-A327 VanDerWaalsContact O-CB 3.25Å; L323-A327 WeakPolarHBondContact O-CB 3.45Å; L323-A327 PolarHBondContact O-N 3.14Å; E325-A327 VanDerWaalsContact C-N 3.25Å; E325-A327 PolarHBondContact O-N 3.42Å; A327-Q330 PolarHBondContact O-NE2 2.94Å; A327-V474 HydrophobicContact CB-CG2 4.32Å; A327-V476 HydrophobicContact CB-CG1 4.27Å; A327-L501 HydrophobicContact CB-CD1 3.96Å; A327-L501 HydrophobicContact CB-CD2 3.72Å; A327-L501 HydrophobicContact CB-CG 4.43Å
328Q98.3Very high98.6Very high68 Ų6829.1 Ų29.132%0.31814%0.142SC..Hα-helixtrans-87.2-24.6176.1-68.4168.999.600112.7Y324 E325 L326 V476 I482Y324-Q328 PolarHBondContact O-N 3.15Å; Y324-Q328 PolarHBondContact O-NE2 2.77Å; E325-Q328 PolarHBondContact O-N 3.5Å; E325-Q328 VanDerWaalsContact O-N 3.12Å; L326-Q328 VanDerWaalsContact C-N 3.28Å; L326-Q328 PolarHBondContact O-N 2.95Å; Q328-V476 HydrophobicContact CG-CG1 3.64Å; Q328-I482 HydrophobicContact CG-CD1 4.15Å
329N98.6Very high98.6Very high44 Ų4430.4 Ų30.424%0.23515%0.147CC..  trans-116.676.7-177.2-58.6-82.9000110.8E325 L326 D331 I332 Q333E325-N329 PolarHBondContact O-N 2.81Å; E325-N329 PolarHBondContact O-ND2 3.47Å; E325-N329 PolarHBondContact OE2-ND2 2.85Å; L326-N329 CarbonylContact O-C 3.54Å; L326-N329 PolarHBondContact O-N 2.86Å; N329-D331 VanDerWaalsContact C-N 3.28Å; N329-D331 PolarHBondContact O-N 3.49Å; N329-I332 HydrophobicContact CB-CB 4.07Å; N329-I332 HydrophobicContact CB-CD1 3.81Å; N329-I332 HydrophobicContact CB-CG1 4.08Å; N329-I332 PolarHBondContact O-N 2.93Å; N329-Q333 PolarHBondContact O-N 3.21Å
330Q98.3Very high98.5Very high51 Ų5130.4 Ų30.424%0.23815%0.147CC..Hα-helixtrans-64.1-31.3-174.2-67.2-63.9-55.900113.2L326 A327 Q333 D334 V474L326-Q330 PolarHBondContact O-NE2 2.85Å; A327-Q330 PolarHBondContact O-NE2 2.94Å; Q330-Q333 WeakPolarHBondContact O-CB 3.47Å; Q330-Q333 PolarHBondContact O-N 3.39Å; Q330-D334 WeakPolarHBondContact O-CB 3.3Å; Q330-D334 PolarHBondContact O-N 2.85Å; Q330-V474 PolarHBondContact NE2-O 3.39Å
331D98.6Very high98.4Very high112 Ų11233.6 Ų33.660%0.59916%0.162SC*.Hα-helixtrans-63.5-43.4174.462.7-55.7000111.9N329 Q333 D334 R335N329-D331 VanDerWaalsContact C-N 3.28Å; N329-D331 PolarHBondContact O-N 3.49Å; D331-Q333 VanDerWaalsContact C-N 3.34Å; D331-D334 PolarHBondContact O-N 2.69Å; D331-R335 WeakPolarHBondContact O-CB 3.11Å; D331-R335 PolarHBondContact O-N 3.27Å
332I98.8Very high98.4Very high13 Ų1336.8 Ų36.87%0.06718%0.182CC..Hα-helixtrans-65.6-41.1174.5-63.1177.7000110.1L326 N329 R335 L336 Y361 V365 F423 P425L326-I332 HydrophobicContact CD2-CB 4.44Å; L326-I332 HydrophobicContact CD2-CG2 3.75Å; N329-I332 HydrophobicContact CB-CB 4.07Å; N329-I332 HydrophobicContact CB-CD1 3.81Å; N329-I332 HydrophobicContact CB-CG1 4.08Å; N329-I332 PolarHBondContact O-N 2.93Å; I332-R335 PolarHBondContact O-N 3.3Å; I332-L336 VanDerWaalsContact O-CB 3.31Å; I332-L336 WeakPolarHBondContact O-CB 3.11Å; I332-L336 PolarHBondContact O-N 3.23Å; I332-Y361 HydrophobicContact CG2-CE1 4.14Å; I332-V365 HydrophobicContact CG2-CG2 4.12Å; I332-F423 HydrophobicContact CD1-CD1 3.76Å; I332-F423 HydrophobicContact CD1-CE1 4.18Å; I332-F423 HydrophobicContact CG2-CE1 4.19Å; I332-P425 HydrophobicContact CD1-CG 4.2Å; I332-P425 HydrophobicContact CG2-CG 3.9Å
333Q98.8Very high98.2Very high0 Ų037.4 Ų37.40%019%0.186CC..Hα-helixtrans-63.6-43.9177.2-166.6-175.2138.100112.4L326 N329 Q330 D331 L336 R337 I469 V474L326-Q333 HydrophobicContact CB-CB 4.24Å; L326-Q333 HydrophobicContact CB-CG 4.2Å; L326-Q333 HydrophobicContact CD2-CB 4.25Å; L326-Q333 PolarHBondContact O-NE2 3.39Å; N329-Q333 PolarHBondContact O-N 3.21Å; Q330-Q333 WeakPolarHBondContact O-CB 3.47Å; Q330-Q333 PolarHBondContact O-N 3.39Å; D331-Q333 VanDerWaalsContact C-N 3.34Å; Q333-L336 PolarHBondContact O-N 2.62Å; Q333-R337 WeakPolarHBondContact O-CB 3.2Å; Q333-R337 PolarHBondContact O-N 3.45Å; Q333-I469 HydrophobicContact CG-CD1 4.07Å; Q333-V474 PolarHBondContact NE2-O 3.19Å
334D98.6Very high98Very high53 Ų5338.3 Ų38.328%0.28319%0.19SC..Hα-helixtrans-66.4-41.8178.9-71.1-21.1000110.8Q330 D331 R337 N338 R473Q330-D334 WeakPolarHBondContact O-CB 3.3Å; Q330-D334 PolarHBondContact O-N 2.85Å; D331-D334 PolarHBondContact O-N 2.69Å; D334-R337 PolarHBondContact O-N 3.45Å; D334-R337 IonicContact OD1-CZ 3.6Å; D334-R337 IonicContact OD1-NH1 2.91Å; D334-R337 PolarHBondContact OD1-NH1 2.91Å; D334-N338 PolarHBondContact O-N 3.49Å; D334-N338 PolarHBondContact O-ND2 2.91Å; D334-N338 PolarHBondContact O-OD1 3.42Å; D334-R473 IonicContact OD1-CZ 3.75Å; D334-R473 IonicContact OD1-NH1 3.58Å; D334-R473 PolarHBondContact OD1-NH1 2.92Å; D334-R473 IonicContact OD1-NH2 3.78Å; D334-R473 PolarHBondContact OD1-NH2 3.33Å; D334-R473 IonicContact OD2-NH1 3.69Å; D334-R473 IonicContact OD2-NH2 3.74Å
335R98.6Very high97.7Very high119 Ų11945.1 Ų45.145%0.44922%0.222SC..Hα-helixtrans-61.9-44.8172.9-179.8174171.5-161.6-2.8112.5D331 I332 R337 N338 E339 Y361 E426D331-R335 WeakPolarHBondContact O-CB 3.11Å; D331-R335 PolarHBondContact O-N 3.27Å; I332-R335 PolarHBondContact O-N 3.3Å; R335-R337 VanDerWaalsContact C-N 3.33Å; R335-N338 PolarHBondContact O-N 3.43Å; R335-E339 PolarHBondContact O-N 2.95Å; R335-E339 VanDerWaalsContact O-N 3.12Å; R335-Y361 HydrophobicContact CB-CE1 4.03Å; R335-Y361 HydrophobicContact CG-CD1 4.07Å; R335-Y361 HydrophobicContact CG-CE1 3.73Å; R335-Y361 VanDerWaalsContact NH1-CE2 3.32Å; R335-Y361 PolarHBondContact NH1-OH 3.06Å; R335-E426 IonicContact CZ-OE1 3.92Å; R335-E426 IonicContact NH1-OE1 2.61Å; R335-E426 PolarHBondContact NH1-OE1 2.76Å; R335-E426 IonicContact NH2-OE1 2.91Å; R335-E426 PolarHBondContact NH2-OE1 3.36Å
336L98.7Very high97.4Very high0 Ų050.8 Ų50.80%025%0.249CC..Hα-helixtrans-61.6-43176.6175.760.9000111.5L326 I332 Q333 N338 E339 I340 Y361 L362 V365 I469L326-L336 HydrophobicContact CD1-CD2 3.76Å; L326-L336 HydrophobicContact CD2-CD2 4.22Å; I332-L336 VanDerWaalsContact O-CB 3.31Å; I332-L336 WeakPolarHBondContact O-CB 3.11Å; I332-L336 PolarHBondContact O-N 3.23Å; Q333-L336 PolarHBondContact O-N 2.62Å; L336-N338 VanDerWaalsContact C-N 3.34Å; L336-N338 PolarHBondContact O-N 3.38Å; L336-E339 PolarHBondContact O-N 2.84Å; L336-I340 HydrophobicContact CD1-CD1 3.92Å; L336-I340 HydrophobicContact CD1-CG1 4.28Å; L336-I340 HydrophobicContact CD2-CD1 4.5Å; L336-I340 HydrophobicContact CG-CD1 3.79Å; L336-I340 WeakPolarHBondContact O-CD1 3.47Å; L336-I340 VanDerWaalsContact O-CG1 3.31Å; L336-I340 WeakPolarHBondContact O-CG1 3.36Å; L336-I340 PolarHBondContact O-N 3.35Å; L336-Y361 HydrophobicContact CB-CD1 4Å; L336-Y361 HydrophobicContact CB-CE1 4.2Å; L336-Y361 HydrophobicContact CD1-CD1 4.19Å; L336-L362 VanDerWaalsContact CD1-CA 3.46Å; L336-L362 HydrophobicContact CD1-CB 3.72Å; L336-L362 HydrophobicContact CD1-CD1 4Å; L336-L362 HydrophobicContact CD1-CG 4.45Å; L336-L362 HydrophobicContact CD2-CD1 4.27Å; L336-V365 HydrophobicContact CD2-CG1 4.23Å; L336-V365 HydrophobicContact CD2-CG2 4.36Å; L336-I469 HydrophobicContact CD2-CG1 4.28Å; L336-I469 HydrophobicContact CD2-CG2 4.28Å; L336-I469 HydrophobicContact CG-CG2 4.18Å
337R98.4Very high96.9Very high11 Ų1154.1 Ų54.14%0.04226%0.264CS..Hα-helixtrans-60.4-44.8176.1-177.3178.3-59.1103.5-0.8111.8Q333 D334 R335 E339 I340 Q341 I469 F472 I506Q333-R337 WeakPolarHBondContact O-CB 3.2Å; Q333-R337 PolarHBondContact O-N 3.45Å; D334-R337 PolarHBondContact O-N 3.45Å; D334-R337 IonicContact OD1-CZ 3.6Å; D334-R337 IonicContact OD1-NH1 2.91Å; D334-R337 PolarHBondContact OD1-NH1 2.91Å; R335-R337 VanDerWaalsContact C-N 3.33Å; R337-E339 VanDerWaalsContact C-N 3.35Å; R337-E339 PolarHBondContact O-N 2.95Å; R337-I340 PolarHBondContact O-N 2.7Å; R337-Q341 HydrophobicContact CG-CG 4.25Å; R337-Q341 WeakPolarHBondContact O-CB 3.06Å; R337-Q341 WeakPolarHBondContact O-CG 3.45Å; R337-Q341 PolarHBondContact O-N 3.4Å; R337-I469 HydrophobicContact CB-CG2 3.85Å; R337-I469 PolarHBondContact NE-O 2.86Å; R337-F472 PolarHBondContact NH2-O 2.85Å; R337-I506 VanDerWaalsContact CD-CD1 3.49Å
338N98.3Very high96.4Very high94 Ų9462.3 Ų62.350%0.50330%0.302SS..Hα-helixtrans-59.1-45.9178.1-68.1-15.2000111D334 R335 L336 I340 Q341 T342D334-N338 PolarHBondContact O-N 3.49Å; D334-N338 PolarHBondContact O-ND2 2.91Å; D334-N338 PolarHBondContact O-OD1 3.42Å; R335-N338 PolarHBondContact O-N 3.43Å; L336-N338 VanDerWaalsContact C-N 3.34Å; L336-N338 PolarHBondContact O-N 3.38Å; N338-I340 PolarHBondContact O-N 3.46Å; N338-Q341 PolarHBondContact O-N 2.89Å; N338-T342 WeakPolarHBondContact O-CB 3.46Å; N338-T342 PolarHBondContact O-N 2.85Å; N338-T342 PolarHBondContact O-OG1 3.42Å
339E98.3Very high95.7Very high40 Ų4061.4 Ų61.419%0.18731%0.311CS..Hα-helixtrans-57-49.6174178.8-175.6-114.900111.4R335 L336 R337 Q341 T342 V343 T360 Y361 L362R335-E339 PolarHBondContact O-N 2.95Å; R335-E339 VanDerWaalsContact O-N 3.12Å; L336-E339 PolarHBondContact O-N 2.84Å; R337-E339 VanDerWaalsContact C-N 3.35Å; R337-E339 PolarHBondContact O-N 2.95Å; E339-Q341 VanDerWaalsContact C-N 3.33Å; E339-Q341 PolarHBondContact O-N 3.25Å; E339-T342 PolarHBondContact O-N 3.38Å; E339-V343 HydrophobicContact CG-CG2 4.36Å; E339-V343 WeakPolarHBondContact O-CB 3.22Å; E339-V343 WeakPolarHBondContact O-CG2 3.23Å; E339-V343 PolarHBondContact O-N 3.07Å; E339-T360 PolarHBondContact OE1-N 3.23Å; E339-T360 PolarHBondContact OE2-N 2.75Å; E339-Y361 VanDerWaalsContact CD-CB 3.46Å; E339-Y361 VanDerWaalsContact CD-N 3.28Å; E339-Y361 WeakPolarHBondContact OE1-CB 3.25Å; E339-Y361 PolarHBondContact OE1-N 2.67Å; E339-Y361 WeakPolarHBondContact OE2-CA 3.3Å; E339-Y361 VanDerWaalsContact OE2-CB 3.31Å; E339-Y361 WeakPolarHBondContact OE2-CB 3.24Å; E339-Y361 PolarHBondContact OE2-N 3.04Å; E339-L362 PolarHBondContact OE2-N 2.85Å
340I97.9Very high95.1Very high0 Ų065 Ų650%033%0.326CS..Hα-helixtrans-61.6-43.5-177.6-66.4159.9000110.7L336 R337 N338 L344 M359 A466 I469L336-I340 HydrophobicContact CD1-CD1 3.92Å; L336-I340 HydrophobicContact CD1-CG1 4.28Å; L336-I340 HydrophobicContact CD2-CD1 4.5Å; L336-I340 HydrophobicContact CG-CD1 3.79Å; L336-I340 WeakPolarHBondContact O-CD1 3.47Å; L336-I340 VanDerWaalsContact O-CG1 3.31Å; L336-I340 WeakPolarHBondContact O-CG1 3.36Å; L336-I340 PolarHBondContact O-N 3.35Å; R337-I340 PolarHBondContact O-N 2.7Å; N338-I340 PolarHBondContact O-N 3.46Å; I340-L344 HydrophobicContact CG2-CD1 3.81Å; I340-L344 HydrophobicContact CG2-CG 4.32Å; I340-L344 WeakPolarHBondContact O-CB 3.36Å; I340-L344 WeakPolarHBondContact O-CG 3.29Å; I340-L344 PolarHBondContact O-N 3.49Å; I340-M359 HydrophobicContact CB-CE 4.5Å; I340-M359 HydrophobicContact CG1-CE 4.49Å; I340-M359 HydrophobicContact CG1-SD 4.08Å; I340-M359 HydrophobicContact CG2-CE 4.02Å; I340-A466 HydrophobicContact CD1-CB 4.47Å; I340-A466 HydrophobicContact CG2-CB 4.38Å; I340-I469 HydrophobicContact CD1-CB 3.94Å; I340-I469 HydrophobicContact CD1-CG2 3.88Å
341Q96.1Very high94.8Very high68 Ų6863.6 Ų63.632%0.31832%0.32SS..Hα-helixtrans-64.7-47.1179.2-74.7178.6-16.900111.5R337 N338 E339 V343 L344 E345R337-Q341 HydrophobicContact CG-CG 4.25Å; R337-Q341 WeakPolarHBondContact O-CB 3.06Å; R337-Q341 WeakPolarHBondContact O-CG 3.45Å; R337-Q341 PolarHBondContact O-N 3.4Å; N338-Q341 PolarHBondContact O-N 2.89Å; E339-Q341 VanDerWaalsContact C-N 3.33Å; E339-Q341 PolarHBondContact O-N 3.25Å; Q341-V343 PolarHBondContact O-N 3.46Å; Q341-L344 PolarHBondContact O-N 2.93Å; Q341-E345 WeakPolarHBondContact O-CG 3.3Å; Q341-E345 PolarHBondContact O-N 2.93Å
342T96.8Very high94.4Very high70 Ų7060.1 Ų60.143%0.42930%0.303SS..Hα-helixtrans-58.2-48.1176.6-60.20000111.7N338 E339 L344 E345 E346N338-T342 WeakPolarHBondContact O-CB 3.46Å; N338-T342 PolarHBondContact O-N 2.85Å; N338-T342 PolarHBondContact O-OG1 3.42Å; E339-T342 PolarHBondContact O-N 3.38Å; T342-L344 VanDerWaalsContact C-N 3.3Å; T342-L344 PolarHBondContact O-N 3.24Å; T342-E345 PolarHBondContact O-N 2.94Å; T342-E346 WeakPolarHBondContact O-CG 3.48Å; T342-E346 PolarHBondContact O-N 3Å
343V96.4Very high93.9Very high13 Ų1362.5 Ų62.58%0.07931%0.312CS..Hα-helixtrans-64.4-35.7179171.50000111.7E339 Q341 Q347 S355 A358 M359E339-V343 HydrophobicContact CG-CG2 4.36Å; E339-V343 WeakPolarHBondContact O-CB 3.22Å; E339-V343 WeakPolarHBondContact O-CG2 3.23Å; E339-V343 PolarHBondContact O-N 3.07Å; Q341-V343 PolarHBondContact O-N 3.46Å; V343-Q347 WeakPolarHBondContact O-CB 3.22Å; V343-Q347 WeakPolarHBondContact O-CG 3.38Å; V343-Q347 PolarHBondContact O-N 3.48Å; V343-S355 WeakPolarHBondContact CG1-O 3.48Å; V343-A358 HydrophobicContact CG1-CB 4.1Å; V343-A358 HydrophobicContact CG2-CB 4.38Å; V343-M359 HydrophobicContact CB-CE 4.25Å; V343-M359 HydrophobicContact CB-CG 4.29Å; V343-M359 HydrophobicContact CG1-CE 3.91Å; V343-M359 HydrophobicContact CG1-CG 4.11Å; V343-M359 HydrophobicContact CG2-CG 4.28Å
344L93.7Very high93.5Very high19 Ų1966.6 Ų66.610%0.09933%0.331CS..Hα-helixtrans-68.3-42175.6-76.2174.2000111.8I340 Q341 T342 E346 Q347 E348 G349 L351I340-L344 HydrophobicContact CG2-CD1 3.81Å; I340-L344 HydrophobicContact CG2-CG 4.32Å; I340-L344 WeakPolarHBondContact O-CB 3.36Å; I340-L344 WeakPolarHBondContact O-CG 3.29Å; I340-L344 PolarHBondContact O-N 3.49Å; Q341-L344 PolarHBondContact O-N 2.93Å; T342-L344 VanDerWaalsContact C-N 3.3Å; T342-L344 PolarHBondContact O-N 3.24Å; L344-E346 VanDerWaalsContact C-N 3.32Å; L344-E346 PolarHBondContact O-N 3.39Å; L344-Q347 CarbonylContact O-C 3.42Å; L344-Q347 VanDerWaalsContact O-C 3.31Å; L344-Q347 PolarHBondContact O-N 3.4Å; L344-E348 PolarHBondContact O-N 3.15Å; L344-G349 WeakPolarHBondContact O-CA 3.43Å; L344-G349 PolarHBondContact O-N 3.13Å; L344-L351 HydrophobicContact CD2-CD2 3.61Å; L344-L351 HydrophobicContact CD2-CG 3.87Å; L344-L351 HydrophobicContact CG-CD2 4.47Å
345E92.9Very high93.1Very high149 Ų14964.1 Ų64.170%0.69632%0.318SS*.Hα-helixtrans-59.6-43176.3-73.9171.3-176.600111.6Q341 T342 Q347 E348Q341-E345 WeakPolarHBondContact O-CG 3.3Å; Q341-E345 PolarHBondContact O-N 2.93Å; T342-E345 PolarHBondContact O-N 2.94Å; E345-Q347 PolarHBondContact O-N 3.19Å; E345-E348 PolarHBondContact O-N 2.98Å
346E91.3Very high92.8Very high138 Ų13858.8 Ų58.865%0.64530%0.298SS*.THydrogen-bonded Turntrans-64.9-17.8174.6-69.8176.7176.100113.8T342 L344T342-E346 WeakPolarHBondContact O-CG 3.48Å; T342-E346 PolarHBondContact O-N 3Å; L344-E346 VanDerWaalsContact C-N 3.32Å; L344-E346 PolarHBondContact O-N 3.39Å
347Q89.2Confident92.4Very high70 Ų7065.4 Ų65.433%0.32733%0.327SS..THydrogen-bonded Turntrans-11729.3-175.8-61.7-71.3-50.600112V343 L344 E345 G349 Q350 T352V343-Q347 WeakPolarHBondContact O-CB 3.22Å; V343-Q347 WeakPolarHBondContact O-CG 3.38Å; V343-Q347 PolarHBondContact O-N 3.48Å; L344-Q347 CarbonylContact O-C 3.42Å; L344-Q347 VanDerWaalsContact O-C 3.31Å; L344-Q347 PolarHBondContact O-N 3.4Å; E345-Q347 PolarHBondContact O-N 3.19Å; Q347-G349 PolarHBondContact O-N 3.09Å; Q347-Q350 PolarHBondContact O-N 3.08Å; Q347-T352 PolarHBondContact OE1-OG1 3.42Å
348E88.6Confident92.2Very high176 Ų17667.4 Ų67.482%0.82235%0.346SS*.THydrogen-bonded Turntrans5731.9176.6-56.5178.4-169.100113.7L344 E345 Q350L344-E348 PolarHBondContact O-N 3.15Å; E345-E348 PolarHBondContact O-N 2.98Å; E348-Q350 VanDerWaalsContact C-N 3.26Å; E348-Q350 PolarHBondContact O-N 3.16Å
349G83.4Confident92.1Very high50 Ų5062.9 Ų62.952%0.51532%0.322SS..THydrogen-bonded Turntrans75.28-179.200000114.8L344 Q347L344-G349 WeakPolarHBondContact O-CA 3.43Å; L344-G349 PolarHBondContact O-N 3.13Å; Q347-G349 PolarHBondContact O-N 3.09Å
350Q85.8Confident92Very high119 Ų11964 Ų6456%0.55633%0.331SS*.  trans-102.4134.8-175.5-60.5-171.710.700112.8Q347 E348 T352Q347-Q350 PolarHBondContact O-N 3.08Å; E348-Q350 VanDerWaalsContact C-N 3.26Å; E348-Q350 PolarHBondContact O-N 3.16Å; Q350-T352 HydrophobicContact CB-CG2 4.12Å; Q350-T352 PolarHBondContact O-N 2.91Å
351L90.8Very high92.1Very high21 Ų2164.7 Ų64.711%0.1133%0.334CS..  trans-7787.8167.2-74174.2000109.8F146 I150 L344 S355 I356 M359 A466 Q467F146-L351 WeakPolarHBondContact CE1-O 3.34Å; F146-L351 WeakPolarHBondContact CZ-O 3.49Å; I150-L351 HydrophobicContact CD1-CB 3.73Å; I150-L351 HydrophobicContact CD1-CD1 4.48Å; I150-L351 WeakPolarHBondContact CD1-O 3.23Å; L344-L351 HydrophobicContact CD2-CD2 3.61Å; L344-L351 HydrophobicContact CD2-CG 3.87Å; L344-L351 HydrophobicContact CG-CD2 4.47Å; L351-S355 WeakPolarHBondContact CA-OG 3.33Å; L351-I356 HydrophobicContact CD2-CD1 3.88Å; L351-M359 HydrophobicContact CD2-CE 3.82Å; L351-A466 HydrophobicContact CD2-CB 4.23Å; L351-Q467 HydrophobicContact CD1-CG 3.69Å
352T91.4Very high92.2Very high40 Ų4061.5 Ų61.525%0.24532%0.319CS..  trans-88165.5171.772.60000111.7F146 Q347 Q350 E354 S355 I356F146-T352 WeakPolarHBondContact CZ-O 3.43Å; Q347-T352 PolarHBondContact OE1-OG1 3.42Å; Q350-T352 HydrophobicContact CB-CG2 4.12Å; Q350-T352 PolarHBondContact O-N 2.91Å; T352-E354 PolarHBondContact O-N 3.17Å; T352-S355 PolarHBondContact N-OG 3.33Å; T352-S355 PolarHBondContact O-N 3.23Å; T352-S355 PolarHBondContact O-OG 2.92Å; T352-S355 PolarHBondContact OG1-N 3.4Å; T352-I356 PolarHBondContact O-N 3.38Å
353Y88.6Confident92.3Very high63 Ų6359.8 Ų59.825%0.24731%0.307CS..Hα-helixtrans-58.9-35.4175.4-171.8-90.1000112.2M142 K143 F146 K357M142-Y353 HydrophobicContact CB-CE2 4.18Å; K143-Y353 HydrophobicContact CB-CD2 4.18Å; K143-Y353 HydrophobicContact CB-CE2 4.23Å; K143-Y353 HydrophobicContact CB-CG 4.46Å; K143-Y353 HydrophobicContact CG-CD2 4.35Å; K143-Y353 HydrophobicContact CG-CG 4.23Å; F146-Y353 HydrophobicContact CB-CD2 4.21Å; F146-Y353 AromaticContact CD2-CD2 3.62Å; F146-Y353 HydrophobicContact CD2-CD2 3.62Å; F146-Y353 HydrophobicContact CD2-CE2 4.48Å; F146-Y353 HydrophobicContact CD2-CG 4.41Å; F146-Y353 HydrophobicContact CE2-CD2 4.19Å; F146-Y353 HydrophobicContact CG-CD2 4.02Å; Y353-K357 PolarHBondContact O-N 3.11Å
354E89.1Confident92.4Very high86 Ų8659.8 Ų59.840%0.40231%0.306SS..Hα-helixtrans-75.3-36.3178.1-55.2-52.114500111.7K143 T352 I356 K357 A358K143-E354 IonicContact NZ-OE1 3.11Å; T352-E354 PolarHBondContact O-N 3.17Å; E354-I356 PolarHBondContact O-N 3.23Å; E354-K357 WeakPolarHBondContact O-CB 3.08Å; E354-K357 PolarHBondContact O-N 3.35Å; E354-K357 VanDerWaalsContact O-N 3.1Å; E354-A358 PolarHBondContact O-N 3.08Å
355S91.6Very high92.6Very high0 Ų058.9 Ų58.90%030%0.302CS..Hα-helixtrans-56.8-48.5174.575.60000111.8V343 L351 T352 K357 A358 M359V343-S355 WeakPolarHBondContact CG1-O 3.48Å; L351-S355 WeakPolarHBondContact CA-OG 3.33Å; T352-S355 PolarHBondContact N-OG 3.33Å; T352-S355 PolarHBondContact O-N 3.23Å; T352-S355 PolarHBondContact O-OG 2.92Å; T352-S355 PolarHBondContact OG1-N 3.4Å; S355-K357 PolarHBondContact O-N 3.18Å; S355-A358 WeakPolarHBondContact O-CB 3.34Å; S355-A358 PolarHBondContact O-N 3.12Å; S355-A358 VanDerWaalsContact O-N 3.07Å; S355-M359 WeakPolarHBondContact O-CG 3.38Å; S355-M359 PolarHBondContact O-N 3.25Å
356I92.4Very high92.9Very high7 Ų752.1 Ų52.14%0.03627%0.27CS..Hα-helixtrans-63.5-31.8178.5-69.6-65.2000111.7F146 L351 T352 E354 M359 R462 I463 A466F146-I356 HydrophobicContact CE2-CB 4.44Å; F146-I356 HydrophobicContact CE2-CG1 3.99Å; F146-I356 HydrophobicContact CZ-CG1 4.04Å; L351-I356 HydrophobicContact CD2-CD1 3.88Å; T352-I356 PolarHBondContact O-N 3.38Å; E354-I356 PolarHBondContact O-N 3.23Å; I356-M359 HydrophobicContact CD1-CE 4.45Å; I356-M359 HydrophobicContact CD1-SD 4.04Å; I356-R462 HydrophobicContact CD1-CB 4.35Å; I356-R462 HydrophobicContact CG2-CB 3.7Å; I356-R462 HydrophobicContact CG2-CG 4.23Å; I356-I463 HydrophobicContact CD1-CG1 4.01Å; I356-I463 HydrophobicContact CG1-CG1 4.08Å; I356-A466 HydrophobicContact CD1-CB 4.25Å
357K90.1Very high93.2Very high140 Ų14046.4 Ų46.461%0.60925%0.246SC*.Hα-helixtrans-73.5-31.5177-173.9-175.7169.7-1630111.8Y353 E354 S355Y353-K357 PolarHBondContact O-N 3.11Å; E354-K357 WeakPolarHBondContact O-CB 3.08Å; E354-K357 PolarHBondContact O-N 3.35Å; E354-K357 VanDerWaalsContact O-N 3.1Å; S355-K357 PolarHBondContact O-N 3.18Å
358A93.1Very high93.7Very high52 Ų5243.1 Ų43.143%0.4323%0.23SC..Hα-helixtrans-74.1-2417900000113.5V343 E354 S355 T360V343-A358 HydrophobicContact CG1-CB 4.1Å; V343-A358 HydrophobicContact CG2-CB 4.38Å; E354-A358 PolarHBondContact O-N 3.08Å; S355-A358 WeakPolarHBondContact O-CB 3.34Å; S355-A358 PolarHBondContact O-N 3.12Å; S355-A358 VanDerWaalsContact O-N 3.07Å; A358-T360 PolarHBondContact O-N 2.84Å; A358-T360 PolarHBondContact O-OG1 3.39Å
359M96.3Very high94.2Very high0 Ų034.8 Ų34.80%019%0.191CC..  trans-7186.6178.4-62.5170.7-173.900111.6I340 V343 L351 S355 I356 L362 N363 A466I340-M359 HydrophobicContact CB-CE 4.5Å; I340-M359 HydrophobicContact CG1-CE 4.49Å; I340-M359 HydrophobicContact CG1-SD 4.08Å; I340-M359 HydrophobicContact CG2-CE 4.02Å; V343-M359 HydrophobicContact CB-CE 4.25Å; V343-M359 HydrophobicContact CB-CG 4.29Å; V343-M359 HydrophobicContact CG1-CE 3.91Å; V343-M359 HydrophobicContact CG1-CG 4.11Å; V343-M359 HydrophobicContact CG2-CG 4.28Å; L351-M359 HydrophobicContact CD2-CE 3.82Å; S355-M359 WeakPolarHBondContact O-CG 3.38Å; S355-M359 PolarHBondContact O-N 3.25Å; I356-M359 HydrophobicContact CD1-CE 4.45Å; I356-M359 HydrophobicContact CD1-SD 4.04Å; M359-L362 HydrophobicContact CB-CB 3.75Å; M359-L362 HydrophobicContact CB-CD2 4.07Å; M359-L362 HydrophobicContact SD-CD2 3.74Å; M359-N363 PolarHBondContact O-N 3.4Å; M359-N363 PolarHBondContact O-ND2 3.28Å; M359-A466 HydrophobicContact SD-CB 4.15Å
360T97.1Very high94.9Very high64 Ų6432.9 Ų32.939%0.39317%0.169SC..Hα-helixtrans-76.6-44.5-174-62.20000111.3E339 A358 N363 Q364E339-T360 PolarHBondContact OE1-N 3.23Å; E339-T360 PolarHBondContact OE2-N 2.75Å; A358-T360 PolarHBondContact O-N 2.84Å; A358-T360 PolarHBondContact O-OG1 3.39Å; T360-N363 VanDerWaalsContact O-CB 3.3Å; T360-N363 WeakPolarHBondContact O-CB 3.5Å; T360-N363 PolarHBondContact O-N 2.94Å; T360-N363 VanDerWaalsContact O-N 3.09Å; T360-Q364 WeakPolarHBondContact O-CG 3.4Å; T360-Q364 PolarHBondContact O-N 3.16Å; T360-Q364 VanDerWaalsContact O-N 3.09Å
361Y98.6Very high95.5Very high14 Ų1427.2 Ų27.26%0.05514%0.143CC..Hα-helixtrans-66.9-36178.1-162.6-112000111.6I332 R335 L336 E339 N363 Q364 V365 P425I332-Y361 HydrophobicContact CG2-CE1 4.14Å; R335-Y361 HydrophobicContact CB-CE1 4.03Å; R335-Y361 HydrophobicContact CG-CD1 4.07Å; R335-Y361 HydrophobicContact CG-CE1 3.73Å; R335-Y361 VanDerWaalsContact NH1-CE2 3.32Å; R335-Y361 PolarHBondContact NH1-OH 3.06Å; L336-Y361 HydrophobicContact CB-CD1 4Å; L336-Y361 HydrophobicContact CB-CE1 4.2Å; L336-Y361 HydrophobicContact CD1-CD1 4.19Å; E339-Y361 VanDerWaalsContact CD-CB 3.46Å; E339-Y361 VanDerWaalsContact CD-N 3.28Å; E339-Y361 WeakPolarHBondContact OE1-CB 3.25Å; E339-Y361 PolarHBondContact OE1-N 2.67Å; E339-Y361 WeakPolarHBondContact OE2-CA 3.3Å; E339-Y361 VanDerWaalsContact OE2-CB 3.31Å; E339-Y361 WeakPolarHBondContact OE2-CB 3.24Å; E339-Y361 PolarHBondContact OE2-N 3.04Å; Y361-N363 PolarHBondContact O-N 3Å; Y361-Q364 HydrophobicContact CD2-CB 4.47Å; Y361-Q364 VanDerWaalsContact CD2-OE1 3.26Å; Y361-Q364 WeakPolarHBondContact O-CB 2.95Å; Y361-Q364 PolarHBondContact O-N 3.06Å; Y361-Q364 VanDerWaalsContact O-N 3.07Å; Y361-V365 HydrophobicContact CD1-CG2 4.05Å; Y361-V365 HydrophobicContact CE1-CG2 3.91Å; Y361-V365 WeakPolarHBondContact O-CG2 3.02Å; Y361-V365 PolarHBondContact O-N 3.16Å; Y361-P425 HydrophobicContact CE2-CB 3.86Å
362L98.6Very high95.9Very high0 Ų026.4 Ų26.40%014%0.138CC..Hα-helixtrans-55.1-41.3168.8179.959.2000112.1L336 E339 M359 Q364 I366 R462 L465 A466L336-L362 VanDerWaalsContact CD1-CA 3.46Å; L336-L362 HydrophobicContact CD1-CB 3.72Å; L336-L362 HydrophobicContact CD1-CD1 4Å; L336-L362 HydrophobicContact CD1-CG 4.45Å; L336-L362 HydrophobicContact CD2-CD1 4.27Å; E339-L362 PolarHBondContact OE2-N 2.85Å; M359-L362 HydrophobicContact CB-CB 3.75Å; M359-L362 HydrophobicContact CB-CD2 4.07Å; M359-L362 HydrophobicContact SD-CD2 3.74Å; L362-Q364 VanDerWaalsContact C-N 3.34Å; L362-I366 HydrophobicContact CD1-CD1 3.99Å; L362-I366 HydrophobicContact CD1-CG1 4.33Å; L362-I366 HydrophobicContact CG-CD1 4.03Å; L362-I366 VanDerWaalsContact O-CG1 3.29Å; L362-I366 WeakPolarHBondContact O-CG1 3.32Å; L362-I366 PolarHBondContact O-N 3.19Å; L362-R462 HydrophobicContact CD2-CB 3.93Å; L362-R462 HydrophobicContact CD2-CG 4.15Å; L362-R462 HydrophobicContact CG-CG 4.43Å; L362-L465 HydrophobicContact CD1-CB 4.04Å; L362-L465 HydrophobicContact CD1-CD1 4.39Å; L362-A466 HydrophobicContact CD2-CB 4.26Å
363N98.1Very high96.1Very high35 Ų3525.1 Ų25.119%0.18713%0.129CC..Hα-helixtrans-66.2-38.1176.3-69.9-43.2000112.5M359 T360 Y361 S367 R462M359-N363 PolarHBondContact O-N 3.4Å; M359-N363 PolarHBondContact O-ND2 3.28Å; T360-N363 VanDerWaalsContact O-CB 3.3Å; T360-N363 WeakPolarHBondContact O-CB 3.5Å; T360-N363 PolarHBondContact O-N 2.94Å; T360-N363 VanDerWaalsContact O-N 3.09Å; Y361-N363 PolarHBondContact O-N 3Å; N363-S367 VanDerWaalsContact O-CB 3.28Å; N363-S367 WeakPolarHBondContact O-CB 3.4Å; N363-S367 PolarHBondContact O-N 3.29Å; N363-S367 PolarHBondContact O-OG 3.42Å; N363-R462 PolarHBondContact OD1-NE 3.01Å; N363-R462 PolarHBondContact OD1-NH2 3.12Å
364Q98.8Very high96.5Very high13 Ų1322.2 Ų22.26%0.06112%0.118CC..Hα-helixtrans-63.6-48.7176.5-68179900111.2T360 Y361 L362 I366 S367 E368 P425 F428T360-Q364 WeakPolarHBondContact O-CG 3.4Å; T360-Q364 PolarHBondContact O-N 3.16Å; T360-Q364 VanDerWaalsContact O-N 3.09Å; Y361-Q364 HydrophobicContact CD2-CB 4.47Å; Y361-Q364 VanDerWaalsContact CD2-OE1 3.26Å; Y361-Q364 WeakPolarHBondContact O-CB 2.95Å; Y361-Q364 PolarHBondContact O-N 3.06Å; Y361-Q364 VanDerWaalsContact O-N 3.07Å; L362-Q364 VanDerWaalsContact C-N 3.34Å; Q364-I366 PolarHBondContact O-N 3.02Å; Q364-S367 PolarHBondContact O-N 3.46Å; Q364-S367 VanDerWaalsContact O-N 3.12Å; Q364-E368 WeakPolarHBondContact O-CB 3.47Å; Q364-E368 PolarHBondContact O-N 3.27Å; Q364-P425 HydrophobicContact CB-CB 4Å; Q364-P425 WeakPolarHBondContact CB-O 3.36Å; Q364-F428 HydrophobicContact CB-CB 4.19Å; Q364-F428 HydrophobicContact CG-CB 4.11Å; Q364-F428 WeakPolarHBondContact CG-O 3.03Å
365V98.9Very high96.9Very high0 Ų018.7 Ų18.70%010%0.102CC..Hα-helixtrans-59-45.6177.7172.30000111.4C322 L326 I332 L336 Y361 S367 T369 F423 P425C322-V365 VanDerWaalsContact SG-CG1 3.59Å; L326-V365 HydrophobicContact CD1-CG1 4.37Å; L326-V365 HydrophobicContact CD2-CG1 4Å; L326-V365 HydrophobicContact CG-CG1 4.35Å; I332-V365 HydrophobicContact CG2-CG2 4.12Å; L336-V365 HydrophobicContact CD2-CG1 4.23Å; L336-V365 HydrophobicContact CD2-CG2 4.36Å; Y361-V365 HydrophobicContact CD1-CG2 4.05Å; Y361-V365 HydrophobicContact CE1-CG2 3.91Å; Y361-V365 WeakPolarHBondContact O-CG2 3.02Å; Y361-V365 PolarHBondContact O-N 3.16Å; V365-S367 VanDerWaalsContact C-N 3.33Å; V365-S367 PolarHBondContact O-N 3.44Å; V365-T369 WeakPolarHBondContact O-CB 3.34Å; V365-T369 PolarHBondContact O-N 3.35Å; V365-T369 PolarHBondContact O-OG1 3.41Å; V365-F423 HydrophobicContact CG1-CE1 4.46Å; V365-F423 HydrophobicContact CG1-CZ 3.96Å; V365-P425 HydrophobicContact CG2-CB 4.05Å; V365-P425 HydrophobicContact CG2-CG 3.84Å
366I98.8Very high97Very high6 Ų621.7 Ų21.73%0.03112%0.12CC..Hα-helixtrans-64.4-40.1176.3-68.4168.5000110.9T318 L362 Q364 T369 L370 R462 L465T318-I366 HydrophobicContact CG2-CG2 4.48Å; L362-I366 HydrophobicContact CD1-CD1 3.99Å; L362-I366 HydrophobicContact CD1-CG1 4.33Å; L362-I366 HydrophobicContact CG-CD1 4.03Å; L362-I366 VanDerWaalsContact O-CG1 3.29Å; L362-I366 WeakPolarHBondContact O-CG1 3.32Å; L362-I366 PolarHBondContact O-N 3.19Å; Q364-I366 PolarHBondContact O-N 3.02Å; I366-T369 WeakPolarHBondContact O-CB 3.12Å; I366-T369 PolarHBondContact O-N 2.77Å; I366-L370 HydrophobicContact CG2-CD1 4.09Å; I366-L370 WeakPolarHBondContact O-CG 2.88Å; I366-L370 PolarHBondContact O-N 3.37Å; I366-R462 HydrophobicContact CD1-CB 4.4Å; I366-R462 HydrophobicContact CD1-CG 3.59Å; I366-L465 HydrophobicContact CD1-CD1 3.82Å; I366-L465 HydrophobicContact CG1-CD1 3.59Å
367S98.7Very high97.1Very high19 Ų1921.5 Ų21.513%0.13312%0.119CC..Hα-helixtrans-69.5-38.8-177.5-58.50000112.2N363 Q364 V365 L370 R371 F428 W441N363-S367 VanDerWaalsContact O-CB 3.28Å; N363-S367 WeakPolarHBondContact O-CB 3.4Å; N363-S367 PolarHBondContact O-N 3.29Å; N363-S367 PolarHBondContact O-OG 3.42Å; Q364-S367 PolarHBondContact O-N 3.46Å; Q364-S367 VanDerWaalsContact O-N 3.12Å; V365-S367 VanDerWaalsContact C-N 3.33Å; V365-S367 PolarHBondContact O-N 3.44Å; S367-L370 PolarHBondContact O-N 2.77Å; S367-R371 PolarHBondContact O-N 3.42Å; S367-F428 VanDerWaalsContact CB-CG 3.46Å; S367-W441 PolarHBondContact O-NE1 3.4Å
368E98.9Very high97.4Very high0 Ų015.6 Ų15.60%09%0.094CC..Hα-helixtrans-67.5-37.9173.1-179.964.5175.700111.6Q364 L370 R371 L372 T422 F423 D424 R427 F428Q364-E368 WeakPolarHBondContact O-CB 3.47Å; Q364-E368 PolarHBondContact O-N 3.27Å; E368-L370 VanDerWaalsContact C-N 3.33Å; E368-L370 PolarHBondContact O-N 3.35Å; E368-R371 WeakPolarHBondContact O-CB 3.14Å; E368-R371 PolarHBondContact O-N 3.05Å; E368-R371 IonicContact OE1-CZ 2.92Å; E368-R371 IonicContact OE1-NE 2.55Å; E368-R371 PolarHBondContact OE1-NE 3.35Å; E368-R371 IonicContact OE1-NH2 2.85Å; E368-R371 PolarHBondContact OE1-NH2 3.45Å; E368-R371 WeakPolarHBondContact OE2-CD 3.43Å; E368-R371 IonicContact OE2-CZ 3.09Å; E368-R371 IonicContact OE2-NE 3.48Å; E368-R371 PolarHBondContact OE2-NE 2.89Å; E368-R371 IonicContact OE2-NH2 2.78Å; E368-L372 PolarHBondContact O-N 3.36Å; E368-T422 VanDerWaalsContact OE1-O 3.06Å; E368-F423 HydrophobicContact CB-CD2 4.31Å; E368-F423 HydrophobicContact CB-CE2 3.94Å; E368-F423 HydrophobicContact CG-CD2 3.43Å; E368-F423 VanDerWaalsContact CG-CD2 3.43Å; E368-F423 HydrophobicContact CG-CE2 3.57Å; E368-F423 HydrophobicContact CG-CG 4.14Å; E368-F423 HydrophobicContact CG-CZ 4.36Å; E368-D424 VanDerWaalsContact CD-O 3.31Å; E368-D424 PolarHBondContact OE1-N 3.49Å; E368-R427 IonicContact OE1-NE 3.08Å; E368-R427 WeakPolarHBondContact OE2-CD 3.24Å; E368-F428 HydrophobicContact CB-CD2 3.99Å; E368-F428 HydrophobicContact CB-CE2 4.11Å; E368-F428 VanDerWaalsContact OE2-CE2 3.24Å; E368-F428 WeakPolarHBondContact OE2-CE2 3.47Å
369T98.8Very high97.7Very high1 Ų114.2 Ų14.21%0.0068%0.079CC..Hα-helixtrans-58-47.4171.7-57.70000110.5C322 V365 I366 R371 L372 Y373C322-T369 HydrophobicContact CB-CG2 3.92Å; V365-T369 WeakPolarHBondContact O-CB 3.34Å; V365-T369 PolarHBondContact O-N 3.35Å; V365-T369 PolarHBondContact O-OG1 3.41Å; I366-T369 WeakPolarHBondContact O-CB 3.12Å; I366-T369 PolarHBondContact O-N 2.77Å; T369-R371 VanDerWaalsContact C-N 3.27Å; T369-R371 PolarHBondContact O-N 2.91Å; T369-L372 PolarHBondContact O-N 3.39Å; T369-Y373 HydrophobicContact CG2-CD2 4.09Å; T369-Y373 WeakPolarHBondContact O-CA 3.33Å; T369-Y373 WeakPolarHBondContact O-CB 3.35Å; T369-Y373 WeakPolarHBondContact O-CD2 3.37Å; T369-Y373 PolarHBondContact O-N 2.92Å
370L98.6Very high97.6Very high10 Ų1015.5 Ų15.55%0.0529%0.085CC..Hα-helixtrans-68.6-24.6179.9-74.1171.5000113.5T318 I366 S367 E368 T374 W441 P443 F444T318-L370 HydrophobicContact CG2-CD2 3.7Å; T318-L370 HydrophobicContact CG2-CG 3.98Å; I366-L370 HydrophobicContact CG2-CD1 4.09Å; I366-L370 WeakPolarHBondContact O-CG 2.88Å; I366-L370 PolarHBondContact O-N 3.37Å; S367-L370 PolarHBondContact O-N 2.77Å; E368-L370 VanDerWaalsContact C-N 3.33Å; E368-L370 PolarHBondContact O-N 3.35Å; L370-T374 PolarHBondContact O-OG1 2.85Å; L370-W441 HydrophobicContact CB-CZ2 4.22Å; L370-W441 HydrophobicContact CD1-CZ2 4.26Å; L370-P443 HydrophobicContact CB-CB 3.77Å; L370-P443 HydrophobicContact CB-CG 3.99Å; L370-P443 HydrophobicContact CD1-CB 4.39Å; L370-P443 HydrophobicContact CD1-CG 4.4Å; L370-P443 HydrophobicContact CD2-CB 4.31Å; L370-P443 HydrophobicContact CG-CB 4.39Å; L370-F444 HydrophobicContact CD1-CE2 3.54Å; L370-F444 HydrophobicContact CD1-CZ 3.7Å
371R98.6Very high97.7Very high0 Ų012.6 Ų12.60%07%0.067CC..Hα-helixtrans-67.8-57.9170.4-172.2-166.16679-3.1110S367 E368 T369 Y373 T374 H411 Y417 P420 T422 F428S367-R371 PolarHBondContact O-N 3.42Å; E368-R371 WeakPolarHBondContact O-CB 3.14Å; E368-R371 PolarHBondContact O-N 3.05Å; E368-R371 IonicContact OE1-CZ 2.92Å; E368-R371 IonicContact OE1-NE 2.55Å; E368-R371 PolarHBondContact OE1-NE 3.35Å; E368-R371 IonicContact OE1-NH2 2.85Å; E368-R371 PolarHBondContact OE1-NH2 3.45Å; E368-R371 WeakPolarHBondContact OE2-CD 3.43Å; E368-R371 IonicContact OE2-CZ 3.09Å; E368-R371 IonicContact OE2-NE 3.48Å; E368-R371 PolarHBondContact OE2-NE 2.89Å; E368-R371 IonicContact OE2-NH2 2.78Å; T369-R371 VanDerWaalsContact C-N 3.27Å; T369-R371 PolarHBondContact O-N 2.91Å; R371-Y373 PolarHBondContact O-N 3Å; R371-T374 PolarHBondContact O-OG1 3.29Å; R371-H411 HydrophobicContact CG-CB 3.75Å; R371-H411 WeakPolarHBondContact CG-O 3.22Å; R371-H411 PolarHBondContact NH1-O 2.89Å; R371-H411 WeakPolarHBondContact O-CB 3.5Å; R371-H411 PolarHBondContact O-ND1 2.89Å; R371-Y417 VanDerWaalsContact CD-CD1 3.46Å; R371-Y417 VanDerWaalsContact CD-CE1 3.5Å; R371-Y417 HydrophobicContact CG-CE1 4.39Å; R371-Y417 HydrophobicContact CG-CE2 4.46Å; R371-P420 VanDerWaalsContact CZ-O 3.26Å; R371-P420 PolarHBondContact NH1-O 2.89Å; R371-P420 PolarHBondContact NH2-O 2.89Å; R371-T422 PolarHBondContact NH2-O 3.46Å; R371-F428 HydrophobicContact CB-CE2 4.19Å; R371-F428 HydrophobicContact CB-CZ 4.09Å
372L97.9Very high97.6Very high4 Ų414 Ų142%0.0217%0.073CC..Hα-helixtrans-63.8-40.6-178.8-76.8-175000112.8E368 T369 R412 P420 F423E368-L372 PolarHBondContact O-N 3.36Å; T369-L372 PolarHBondContact O-N 3.39Å; L372-R412 PolarHBondContact O-NH2 2.91Å; L372-P420 WeakPolarHBondContact CD2-O 3.45Å; L372-F423 HydrophobicContact CD1-CB 3.93Å; L372-F423 HydrophobicContact CD1-CD2 3.71Å; L372-F423 HydrophobicContact CD1-CG 4.32Å
373Y97.5Very high97.6Very high14 Ų1414 Ų146%0.0557%0.074CC..SBendtrans-112.767.6-173.6-59.1-87.5000111.2Y321 Y324 E325 T369 R371 L375 L484 Y486 L493Y321-Y373 AromaticContact CD1-CD1 3.5Å; Y321-Y373 HydrophobicContact CD1-CD1 3.5Å; Y321-Y373 AromaticContact CD1-CE1 3.66Å; Y321-Y373 HydrophobicContact CD1-CE1 3.66Å; Y321-Y373 HydrophobicContact CD1-CG 4.1Å; Y321-Y373 AromaticContact CD2-CD1 3.83Å; Y321-Y373 HydrophobicContact CD2-CD1 3.83Å; Y321-Y373 AromaticContact CD2-CG 3.8Å; Y321-Y373 HydrophobicContact CD2-CG 3.8Å; Y321-Y373 AromaticContact CE1-CD1 3.91Å; Y321-Y373 HydrophobicContact CE1-CD1 3.91Å; Y321-Y373 HydrophobicContact CE1-CE1 4.17Å; Y321-Y373 HydrophobicContact CE2-CD1 4.2Å; Y321-Y373 HydrophobicContact CE2-CG 4.49Å; Y321-Y373 AromaticContact CG-CD1 3.48Å; Y321-Y373 HydrophobicContact CG-CD1 3.48Å; Y321-Y373 VanDerWaalsContact CG-CD1 3.48Å; Y321-Y373 HydrophobicContact CG-CD2 4.19Å; Y321-Y373 HydrophobicContact CG-CE1 4.01Å; Y321-Y373 AromaticContact CG-CG 3.58Å; Y321-Y373 HydrophobicContact CG-CG 3.58Å; Y324-Y373 WeakPolarHBondContact CD1-OH 3.24Å; Y324-Y373 VanDerWaalsContact CE1-OH 3.25Å; Y324-Y373 WeakPolarHBondContact CE1-OH 3.34Å; E325-Y373 HydrophobicContact CG-CE2 3.66Å; E325-Y373 VanDerWaalsContact OE1-CE2 3.24Å; E325-Y373 WeakPolarHBondContact OE1-CE2 3.23Å; E325-Y373 VanDerWaalsContact OE1-CZ 3.23Å; E325-Y373 PolarHBondContact OE1-OH 2.96Å; T369-Y373 HydrophobicContact CG2-CD2 4.09Å; T369-Y373 WeakPolarHBondContact O-CA 3.33Å; T369-Y373 WeakPolarHBondContact O-CB 3.35Å; T369-Y373 WeakPolarHBondContact O-CD2 3.37Å; T369-Y373 PolarHBondContact O-N 2.92Å; R371-Y373 PolarHBondContact O-N 3Å; Y373-L375 PolarHBondContact O-N 3.49Å; Y373-L484 HydrophobicContact CE1-CD1 4.11Å; Y373-Y486 HydrophobicContact CD1-CE1 4.48Å; Y373-Y486 WeakPolarHBondContact CE1-OH 3.38Å; Y373-L493 HydrophobicContact CD1-CD2 4.16Å
374T97Very high97.6Very high1 Ų114.8 Ų14.81%0.0068%0.077CC..  trans-7288.1-175.6-51.70000111.6H53 L370 R371 V376 A407 C408 H411H53-T374 PolarHBondContact CE1-O 3.48Å; H53-T374 PolarHBondContact NE2-O 3.45Å; H53-T374 VanDerWaalsContact NE2-O 3.12Å; L370-T374 PolarHBondContact O-OG1 2.85Å; R371-T374 PolarHBondContact O-OG1 3.29Å; T374-V376 VanDerWaalsContact C-N 3.28Å; T374-V376 WeakPolarHBondContact CG2-O 3.37Å; T374-V376 CarbonylContact O-C 3.34Å; T374-V376 PolarHBondContact O-N 3.23Å; T374-A407 HydrophobicContact CG2-CB 4.13Å; T374-C408 HydrophobicContact CG2-CB 4.3Å; T374-H411 PolarHBondContact OG1-ND1 2.81Å
375L95.5Very high97.6Very high13 Ų1318.5 Ų18.57%0.06810%0.098CC..SBendtrans-52.3-40.5-168.8-61-178.5000115.3T314 T318 Y321 Y373 P377 V492 L493T314-L375 HydrophobicContact CG2-CD1 4.25Å; T314-L375 WeakPolarHBondContact O-CD1 3.05Å; T318-L375 WeakPolarHBondContact OG1-CD1 3.38Å; Y321-L375 HydrophobicContact CD2-CD2 4.01Å; Y321-L375 HydrophobicContact CE2-CD2 3.58Å; Y373-L375 PolarHBondContact O-N 3.49Å; L375-P377 WeakPolarHBondContact O-CD 3.16Å; L375-V492 CarbonylContact O-C 3.47Å; L375-V492 VanDerWaalsContact O-CA 3.28Å; L375-V492 WeakPolarHBondContact O-CA 3.24Å; L375-V492 WeakPolarHBondContact O-CB 3.24Å; L375-L493 HydrophobicContact CD2-CB 4.4Å; L375-L493 PolarHBondContact O-N 2.79Å
376V95Very high97.6Very high63 Ų6323.6 Ų23.638%0.38213%0.125SC..SBendtrans-104100.8171.2-178.60000107.6T374 H378T374-V376 VanDerWaalsContact C-N 3.28Å; T374-V376 WeakPolarHBondContact CG2-O 3.37Å; T374-V376 CarbonylContact O-C 3.34Å; T374-V376 PolarHBondContact O-N 3.23Å; V376-H378 WeakPolarHBondContact CG1-O 3.45Å; V376-H378 PolarHBondContact O-N 3.04Å; V376-H378 VanDerWaalsContact O-N 3.15Å
377P95Very high97.6Very high2 Ų224.3 Ų24.31%0.01313%0.127CC..  trans-66.6-21.4-165.517.5-27.7000115.2M52 F56 L375 A407 C408M52-P377 HydrophobicContact CB-CB 4.37Å; M52-P377 HydrophobicContact CB-CG 3.59Å; M52-P377 HydrophobicContact CE-CG 4.25Å; M52-P377 HydrophobicContact SD-CG 4.49Å; F56-P377 HydrophobicContact CD2-CB 4.06Å; F56-P377 HydrophobicContact CE2-CB 4.33Å; F56-P377 HydrophobicContact CE2-CG 4.32Å; L375-P377 WeakPolarHBondContact O-CD 3.16Å; P377-A407 PolarHBondContact O-N 2.89Å; P377-A407 VanDerWaalsContact O-N 3.14Å; P377-C408 HydrophobicContact CB-CB 4.04Å; P377-C408 PolarHBondContact O-N 2.98Å; P377-C408 PolarHBondContact O-SG 2.96Å
378H96.4Very high97.5Very high17 Ų1727.3 Ų27.38%0.07915%0.145CC..  trans-144.3152.9-177.168.8-63.2000111.7F56 V376 E380 I404 I405F56-H378 HydrophobicContact CD2-CB 3.91Å; F56-H378 HydrophobicContact CE2-CB 3.64Å; F56-H378 AromaticContact CE2-CE1 3.87Å; F56-H378 AromaticContact CE2-CG 3.39Å; F56-H378 AromaticContact CE2-ND1 3.2Å; F56-H378 WeakPolarHBondContact CE2-ND1 3.45Å; F56-H378 HydrophobicContact CZ-CB 4.18Å; F56-H378 AromaticContact CZ-CD2 3.99Å; F56-H378 AromaticContact CZ-CE1 3.98Å; F56-H378 AromaticContact CZ-CG 3.7Å; F56-H378 AromaticContact CZ-ND1 3.71Å; V376-H378 WeakPolarHBondContact CG1-O 3.45Å; V376-H378 PolarHBondContact O-N 3.04Å; V376-H378 VanDerWaalsContact O-N 3.15Å; H378-E380 VanDerWaalsContact CD2-CG 3.49Å; H378-E380 WeakPolarHBondContact CD2-CG 3.47Å; H378-E380 IonicContact CD2-OE1 3.67Å; H378-E380 IonicContact CE1-OE1 3.53Å; H378-E380 WeakPolarHBondContact NE2-CG 3.49Å; H378-E380 IonicContact NE2-OE1 2.66Å; H378-E380 PolarHBondContact NE2-OE1 3.49Å; H378-I404 HydrophobicContact CB-CG2 4Å; H378-I405 CarbonylContact C-O 3.06Å; H378-I405 WeakPolarHBondContact CA-O 3.32Å; H378-I405 WeakPolarHBondContact CB-O 3.35Å
379L97.7Very high97.5Very high22 Ų2227.5 Ų27.512%0.11515%0.146CC..EExtended strand (participates in β ladder)trans-101.9140.4169.1-49.5176.8000109.3L93 I405 L442L93-L379 HydrophobicContact CD1-CD1 3.95Å; L93-L379 HydrophobicContact CD2-CD1 4.05Å; L379-I405 HydrophobicContact CB-CB 4.22Å; L379-I405 PolarHBondContact N-O 2.76Å; L379-I405 PolarHBondContact O-N 2.98Å; L379-L442 HydrophobicContact CD1-CB 4.3Å; L379-L442 HydrophobicContact CD1-CD1 4.06Å; L379-L442 HydrophobicContact CD1-CD2 4.11Å; L379-L442 HydrophobicContact CD1-CG 4.41Å
380E96Very high97.3Very high28 Ų2830.9 Ų30.913%0.13117%0.168CC..EExtended strand (participates in β ladder)trans-111139.8178.9-71.5177.8161.300110.6Q105 H378 V403Q105-E380 PolarHBondContact NE2-OE2 3.19Å; H378-E380 VanDerWaalsContact CD2-CG 3.49Å; H378-E380 WeakPolarHBondContact CD2-CG 3.47Å; H378-E380 IonicContact CD2-OE1 3.67Å; H378-E380 IonicContact CE1-OE1 3.53Å; H378-E380 WeakPolarHBondContact NE2-CG 3.49Å; H378-E380 IonicContact NE2-OE1 2.66Å; H378-E380 PolarHBondContact NE2-OE1 3.49Å; E380-V403 WeakPolarHBondContact CA-O 3.39Å
381R97.9Very high97.1Very high3 Ų334.3 Ų34.31%0.01121%0.205CC..EExtended strand (participates in β ladder)trans-137.8171.3167.2-62-60-170.8-92.4-1.2110.3I92 L93 F100 D102 Q402 V403I92-R381 HydrophobicContact CG2-CB 4.23Å; I92-R381 HydrophobicContact CG2-CG 3.97Å; L93-R381 HydrophobicContact CD2-CG 4.48Å; L93-R381 VanDerWaalsContact CD2-NH2 3.3Å; F100-R381 HydrophobicContact CB-CB 4.09Å; F100-R381 HydrophobicContact CB-CG 4.34Å; F100-R381 HydrophobicContact CD1-CB 4.48Å; F100-R381 WeakPolarHBondContact O-CD 3.34Å; D102-R381 CarbonylContact O-C 3.52Å; D102-R381 VanDerWaalsContact O-C 3.32Å; D102-R381 VanDerWaalsContact O-CA 3.25Å; D102-R381 WeakPolarHBondContact O-CA 3.32Å; R381-Q402 PolarHBondContact O-NE2 3.06Å; R381-V403 HydrophobicContact CB-CB 4.07Å; R381-V403 PolarHBondContact N-O 2.89Å; R381-V403 PolarHBondContact O-N 2.91Å
382K97.5Very high97Very high43 Ų4337.8 Ų37.819%0.18722%0.221CC..EExtended strand (participates in β ladder)trans-137.1128.4175-178-177174.7-1700109.7D102 L384 T401D102-K382 HydrophobicContact CB-CB 4.29Å; D102-K382 PolarHBondContact O-N 3.39Å; K382-L384 PolarHBondContact O-N 3.43Å; K382-T401 WeakPolarHBondContact CA-O 3.34Å
383A98.3Very high96.7Very high1 Ų145.9 Ų45.91%0.00826%0.259CS..  trans-65.7124.6175.100000110.4N99 F100 I397 E398 G400 T401N99-A383 CarbonylContact O-C 3.38Å; F100-A383 HydrophobicContact CD1-CB 4.31Å; F100-A383 HydrophobicContact CE1-CB 3.82Å; A383-I397 HydrophobicContact CB-CG2 3.94Å; A383-E398 WeakPolarHBondContact CB-O 3.38Å; A383-G400 WeakPolarHBondContact O-CA 3.49Å; A383-G400 PolarHBondContact O-N 3.48Å; A383-T401 PolarHBondContact N-O 3Å; A383-T401 VanDerWaalsContact N-O 3.08Å
384L98Very high96.5Very high51 Ų5154.5 Ų54.527%0.26730%0.297SS..SBendtrans-86.6-27.6178-62.5-174.2000112.2N99 A101 D102 K382 K399N99-L384 WeakPolarHBondContact O-CB 3.49Å; N99-L384 WeakPolarHBondContact O-CG 3.44Å; N99-L384 PolarHBondContact O-N 2.9Å; A101-L384 HydrophobicContact CB-CD1 4.31Å; D102-L384 HydrophobicContact CB-CD2 4.02Å; D102-L384 WeakPolarHBondContact OD2-CD2 3.42Å; K382-L384 PolarHBondContact O-N 3.43Å; L384-K399 VanDerWaalsContact O-CD 3.24Å; L384-K399 WeakPolarHBondContact O-CD 3.45Å; L384-K399 WeakPolarHBondContact O-CE 3.4Å; L384-K399 VanDerWaalsContact O-CG 3.27Å; L384-K399 WeakPolarHBondContact O-CG 2.92Å
385N98.4Very high96.5Very high91 Ų9155.1 Ų55.149%0.48730%0.3SS..SBendtrans-138.5163.9173.4-51.8-71.2000109.4N99 Y387N99-N385 PolarHBondContact ND2-O 2.86Å; N99-N385 WeakPolarHBondContact OD1-CA 3.45Å; N99-N385 VanDerWaalsContact OD1-CB 3.28Å; N99-N385 WeakPolarHBondContact OD1-CB 3.49Å; N99-N385 PolarHBondContact OD1-N 2.97Å; N99-N385 PolarHBondContact OD1-ND2 3.36Å; N99-N385 VanDerWaalsContact OD1-ND2 3.12Å; N99-N385 PolarHBondContact OD1-O 3.19Å; N385-Y387 PolarHBondContact O-N 3.04Å
386D98.4Very high96.6Very high107 Ų10756.8 Ų56.857%0.57231%0.31SS*.  trans-57.9133.2173.6-65.4-9.2000109.8V396 E398 K399D386-V396 HydrophobicContact CB-CG1 4.11Å; D386-E398 WeakPolarHBondContact OD1-CA 3.29Å; D386-K399 WeakPolarHBondContact OD1-CB 3.41Å; D386-K399 PolarHBondContact OD1-N 2.57Å
387Y98.5Very high96.7Very high21 Ų2153.8 Ų53.88%0.08229%0.292CS..EExtended strand (participates in β ladder)trans-124.4108.1-176.8-177.7-99.2000109.9L88 D96 F100 N385 V389 P390 V396 I397L88-Y387 HydrophobicContact CD1-CE1 3.85Å; D96-Y387 HydrophobicContact CB-CE2 3.9Å; D96-Y387 VanDerWaalsContact OD2-CE2 3.29Å; D96-Y387 WeakPolarHBondContact OD2-CE2 3.44Å; D96-Y387 PolarHBondContact OD2-OH 2.96Å; F100-Y387 HydrophobicContact CE2-CD1 4.21Å; F100-Y387 AromaticContact CE2-CD2 3.77Å; F100-Y387 HydrophobicContact CE2-CD2 3.77Å; F100-Y387 HydrophobicContact CE2-CE1 4.38Å; F100-Y387 AromaticContact CE2-CE2 3.95Å; F100-Y387 HydrophobicContact CE2-CE2 3.95Å; F100-Y387 AromaticContact CE2-CG 3.89Å; F100-Y387 HydrophobicContact CE2-CG 3.89Å; F100-Y387 AromaticContact CZ-CD1 3.79Å; F100-Y387 HydrophobicContact CZ-CD1 3.79Å; F100-Y387 AromaticContact CZ-CD2 3.94Å; F100-Y387 HydrophobicContact CZ-CD2 3.94Å; F100-Y387 HydrophobicContact CZ-CE1 4.32Å; F100-Y387 HydrophobicContact CZ-CE2 4.45Å; F100-Y387 AromaticContact CZ-CG 3.56Å; F100-Y387 HydrophobicContact CZ-CG 3.56Å; N385-Y387 PolarHBondContact O-N 3.04Å; Y387-V389 HydrophobicContact CD1-CG2 4.31Å; Y387-V389 HydrophobicContact CE1-CG2 4.35Å; Y387-P390 WeakPolarHBondContact OH-CD 3.48Å; Y387-V396 CarbonylContact O-C 3.42Å; Y387-V396 WeakPolarHBondContact O-CA 3.41Å; Y387-I397 HydrophobicContact CD1-CD1 4.28Å; Y387-I397 PolarHBondContact N-O 3.03Å; Y387-I397 PolarHBondContact O-N 2.85Å
388V98.2Very high96.9Very high82 Ų8256.4 Ų56.450%0.49731%0.305SS..EExtended strand (participates in β ladder)trans-74.3123.1170.9-176.20000107.7P390 V396V388-P390 WeakPolarHBondContact O-CD 3.35Å; V388-V396 HydrophobicContact CG2-CG2 4.19Å
389V97.5Very high96.9Very high4 Ų462.3 Ų62.32%0.02433%0.33CS..EExtended strand (participates in β ladder)trans-68.6124.6-178.1176.60000109.6P69 F70 L88 Y387 G391 H392 L395 I397P69-V389 HydrophobicContact CB-CG1 4.18Å; P69-V389 HydrophobicContact CG-CG1 3.73Å; F70-V389 HydrophobicContact CD1-CG2 3.92Å; F70-V389 HydrophobicContact CE1-CG2 3.65Å; L88-V389 HydrophobicContact CD1-CG1 4.11Å; L88-V389 HydrophobicContact CD1-CG2 4.41Å; L88-V389 HydrophobicContact CD2-CG1 4.17Å; L88-V389 HydrophobicContact CD2-CG2 4.22Å; Y387-V389 HydrophobicContact CD1-CG2 4.31Å; Y387-V389 HydrophobicContact CE1-CG2 4.35Å; V389-G391 PolarHBondContact O-N 3.15Å; V389-H392 HydrophobicContact CB-CB 4.15Å; V389-H392 HydrophobicContact CG1-CB 4.16Å; V389-H392 CarbonylContact O-C 3.58Å; V389-H392 WeakPolarHBondContact O-CA 3.27Å; V389-H392 PolarHBondContact O-N 2.79Å; V389-L395 HydrophobicContact CB-CB 4.35Å; V389-L395 HydrophobicContact CG2-CB 4.34Å; V389-L395 PolarHBondContact N-O 3.1Å; V389-I397 HydrophobicContact CG2-CD1 4.48Å; V389-I397 HydrophobicContact CG2-CG1 4.37Å
390P95.6Very high96.8Very high72 Ų7262.8 Ų62.847%0.46834%0.34SS..THydrogen-bonded Turntrans-54.7130.5177.7-27.936.1000111.7Y387 V388 H392Y387-P390 WeakPolarHBondContact OH-CD 3.48Å; V388-P390 WeakPolarHBondContact O-CD 3.35Å; P390-H392 PolarHBondContact O-N 3.46Å
391G94.7Very high96.8Very high81 Ų8161.9 Ų61.984%0.83534%0.337SS*.THydrogen-bonded Turntrans79.4-4.9-175.600000115.2V389V389-G391 PolarHBondContact O-N 3.15Å
392H94.9Very high96.8Very high73 Ų7362 Ų6234%0.33834%0.338SS..EExtended strand (participates in β ladder)trans-136.371-178.8-61.2-94.4000111.4P69 V389 P390 K394 L395P69-H392 HydrophobicContact CG-CB 4.49Å; V389-H392 HydrophobicContact CB-CB 4.15Å; V389-H392 HydrophobicContact CG1-CB 4.16Å; V389-H392 CarbonylContact O-C 3.58Å; V389-H392 WeakPolarHBondContact O-CA 3.27Å; V389-H392 PolarHBondContact O-N 2.79Å; P390-H392 PolarHBondContact O-N 3.46Å; H392-K394 PolarHBondContact O-N 3.08Å; H392-L395 HydrophobicContact CB-CB 4.03Å; H392-L395 HydrophobicContact CB-CD1 3.82Å; H392-L395 HydrophobicContact CB-CG 4.02Å; H392-L395 PolarHBondContact O-N 3.14Å
393E92.8Very high96.8Very high174 Ų17460 Ų6081%0.81333%0.329SS*.EExtended strand (participates in β ladder)trans-55.9-26.6-172.4-63.9158.8176.500115
394K93Very high96.8Very high196 Ų19660 Ų6085%0.85233%0.328SS*.EExtended strand (participates in β ladder)trans-84-11.7178.2-63.8-178-179176.50113.5H392H392-K394 PolarHBondContact O-N 3.08Å
395L96.5Very high96.8Very high14 Ų1457.5 Ų57.57%0.07332%0.315CS..EExtended strand (participates in β ladder)trans-101.8113.3-178.3-60.3-176.1000109.6V31 F68 P69 F70 V389 H392V31-L395 HydrophobicContact CG2-CD2 4.34Å; F68-L395 HydrophobicContact CD1-CD1 3.87Å; F68-L395 HydrophobicContact CD1-CD2 4.23Å; F68-L395 HydrophobicContact CE1-CD1 4.49Å; F68-L395 HydrophobicContact CE1-CD2 4.25Å; P69-L395 HydrophobicContact CG-CD1 3.79Å; F70-L395 HydrophobicContact CE1-CB 3.88Å; F70-L395 HydrophobicContact CZ-CB 4.34Å; V389-L395 HydrophobicContact CB-CB 4.35Å; V389-L395 HydrophobicContact CG2-CB 4.34Å; V389-L395 PolarHBondContact N-O 3.1Å; H392-L395 HydrophobicContact CB-CB 4.03Å; H392-L395 HydrophobicContact CB-CD1 3.82Å; H392-L395 HydrophobicContact CB-CG 4.02Å; H392-L395 PolarHBondContact O-N 3.14Å
396V97.8Very high96.8Very high47 Ų4753.2 Ų53.229%0.28529%0.292SS..EExtended strand (participates in β ladder)trans-121.8125.1-178.6-175.30000109.8D386 Y387 V388 E398D386-V396 HydrophobicContact CB-CG1 4.11Å; Y387-V396 CarbonylContact O-C 3.42Å; Y387-V396 WeakPolarHBondContact O-CA 3.41Å; V388-V396 HydrophobicContact CG2-CG2 4.19Å; V396-E398 PolarHBondContact O-N 3.4Å
397I98.3Very high96.8Very high0 Ų048.1 Ų48.10%027%0.265CS..EExtended strand (participates in β ladder)trans-86.1101.2165.4-54.8175.4000106.7F70 A81 I83 I92 F100 A383 Y387 V389 T401 V403F70-I397 HydrophobicContact CD1-CD1 4.35Å; F70-I397 HydrophobicContact CD1-CG1 4.2Å; F70-I397 HydrophobicContact CE1-CD1 4.44Å; F70-I397 HydrophobicContact CE1-CG1 3.82Å; F70-I397 HydrophobicContact CZ-CG1 4.04Å; A81-I397 HydrophobicContact CB-CD1 4.25Å; A81-I397 HydrophobicContact CB-CG1 4.23Å; A81-I397 HydrophobicContact CB-CG2 4.29Å; I83-I397 HydrophobicContact CD1-CD1 4.28Å; I92-I397 HydrophobicContact CD1-CD1 4.19Å; F100-I397 HydrophobicContact CE1-CG2 4.49Å; A383-I397 HydrophobicContact CB-CG2 3.94Å; Y387-I397 HydrophobicContact CD1-CD1 4.28Å; Y387-I397 PolarHBondContact N-O 3.03Å; Y387-I397 PolarHBondContact O-N 2.85Å; V389-I397 HydrophobicContact CG2-CD1 4.48Å; V389-I397 HydrophobicContact CG2-CG1 4.37Å; I397-T401 HydrophobicContact CG2-CG2 4.17Å; I397-V403 HydrophobicContact CD1-CG2 4.5Å; I397-V403 HydrophobicContact CG2-CG2 4.07Å
398E97.6Very high96.8Very high58 Ų5847.1 Ų47.127%0.27126%0.261SS..  trans-67.3152.7-176.5-65.8176.2166.200112.4Y25 R29 A383 D386 V396 G400 T401Y25-E398 VanDerWaalsContact CE2-OE2 3.26Å; Y25-E398 WeakPolarHBondContact CE2-OE2 3.39Å; Y25-E398 PolarHBondContact OH-OE2 2.69Å; R29-E398 VanDerWaalsContact CZ-CD 3.49Å; R29-E398 IonicContact CZ-OE1 2.73Å; R29-E398 IonicContact CZ-OE2 3.31Å; R29-E398 IonicContact NE-OE1 3.73Å; R29-E398 PolarHBondContact NE-OE1 3.11Å; R29-E398 IonicContact NE-OE2 2.74Å; R29-E398 PolarHBondContact NE-OE2 3.33Å; R29-E398 IonicContact NH2-OE1 3.93Å; R29-E398 PolarHBondContact NH2-OE1 2.91Å; R29-E398 IonicContact NH2-OE2 2.64Å; R29-E398 PolarHBondContact NH2-OE2 3.49Å; A383-E398 WeakPolarHBondContact CB-O 3.38Å; D386-E398 WeakPolarHBondContact OD1-CA 3.29Å; V396-E398 PolarHBondContact O-N 3.4Å; E398-G400 PolarHBondContact O-N 2.77Å; E398-T401 WeakPolarHBondContact O-CB 3.48Å; E398-T401 PolarHBondContact O-N 2.85Å; E398-T401 PolarHBondContact O-OG1 3.36Å
399K97.8Very high96.8Very high140 Ų14043.2 Ų43.261%0.60924%0.238SC*.THydrogen-bonded Turntrans-48130.1171.6175.8167.5-175.2165.20111.8L384 D386 T401L384-K399 VanDerWaalsContact O-CD 3.24Å; L384-K399 WeakPolarHBondContact O-CD 3.45Å; L384-K399 WeakPolarHBondContact O-CE 3.4Å; L384-K399 VanDerWaalsContact O-CG 3.27Å; L384-K399 WeakPolarHBondContact O-CG 2.92Å; D386-K399 WeakPolarHBondContact OD1-CB 3.41Å; D386-K399 PolarHBondContact OD1-N 2.57Å; K399-T401 VanDerWaalsContact C-N 3.27Å; K399-T401 PolarHBondContact O-N 2.8Å
400G95.2Very high96.8Very high32 Ų3243 Ų4333%0.3324%0.237SC..THydrogen-bonded Turntrans86.2-9.4178.700000114.4A383 E398A383-G400 WeakPolarHBondContact O-CA 3.49Å; A383-G400 PolarHBondContact O-N 3.48Å; E398-G400 PolarHBondContact O-N 2.77Å
401T96.7Very high97Very high10 Ų1039.6 Ų39.66%0.06121%0.214CC..  trans-65.3133.5176.3-54.90000110.1Y25 W26 A81 K382 A383 I397 E398 K399Y25-T401 PolarHBondContact OH-OG1 3.48Å; W26-T401 HydrophobicContact CH2-CG2 3.97Å; W26-T401 HydrophobicContact CZ2-CG2 4.17Å; A81-T401 HydrophobicContact CB-CG2 4.36Å; K382-T401 WeakPolarHBondContact CA-O 3.34Å; A383-T401 PolarHBondContact N-O 3Å; A383-T401 VanDerWaalsContact N-O 3.08Å; I397-T401 HydrophobicContact CG2-CG2 4.17Å; E398-T401 WeakPolarHBondContact O-CB 3.48Å; E398-T401 PolarHBondContact O-N 2.85Å; E398-T401 PolarHBondContact O-OG1 3.36Å; K399-T401 VanDerWaalsContact C-N 3.27Å; K399-T401 PolarHBondContact O-N 2.8Å
402Q96.7Very high97.1Very high6 Ų637.5 Ų37.53%0.02818%0.181CC..EExtended strand (participates in β ladder)trans-72.2144.3172.3-165.768.730.200108.9A80 A81 R103 R381A80-Q402 CarbonylContact C-O 3.18Å; A80-Q402 WeakPolarHBondContact CA-O 3.4Å; A80-Q402 HydrophobicContact CB-CB 3.88Å; A80-Q402 HydrophobicContact CB-CG 4.36Å; A81-Q402 PolarHBondContact N-O 3.49Å; R103-Q402 PolarHBondContact O-NE2 3.37Å; R103-Q402 PolarHBondContact O-OE1 3.33Å; R381-Q402 PolarHBondContact O-NE2 3.06Å
403V98.4Very high97.2Very high0 Ų034.3 Ų34.30%017%0.167CC..EExtended strand (participates in β ladder)trans-117.3133.7173.8174.70000108.1A81 I83 I92 F100 E380 R381 I397 I405A81-V403 HydrophobicContact CB-CG2 4.43Å; A81-V403 CarbonylContact O-C 3.54Å; A81-V403 WeakPolarHBondContact O-CA 3.14Å; I83-V403 HydrophobicContact CD1-CG1 3.78Å; I83-V403 HydrophobicContact CG1-CG1 3.51Å; I92-V403 HydrophobicContact CD1-CG1 3.96Å; I92-V403 HydrophobicContact CG2-CG1 4.26Å; F100-V403 HydrophobicContact CD1-CG2 4.18Å; F100-V403 HydrophobicContact CE1-CG2 3.98Å; E380-V403 WeakPolarHBondContact CA-O 3.39Å; R381-V403 HydrophobicContact CB-CB 4.07Å; R381-V403 PolarHBondContact N-O 2.89Å; R381-V403 PolarHBondContact O-N 2.91Å; I397-V403 HydrophobicContact CD1-CG2 4.5Å; I397-V403 HydrophobicContact CG2-CG2 4.07Å; V403-I405 HydrophobicContact CG1-CG1 4.3Å
404I98.1Very high97.4Very high0 Ų030.8 Ų30.80%015%0.15CC..EExtended strand (participates in β ladder)trans-118.8122176.5-64171.4000107.8F56 F73 F75 A80 A81 F82 I83 H378F56-I404 HydrophobicContact CE1-CG2 4.21Å; F73-I404 HydrophobicContact CD1-CD1 3.59Å; F73-I404 HydrophobicContact CE1-CD1 3.85Å; F73-I404 HydrophobicContact CG-CD1 4.5Å; F75-I404 HydrophobicContact CB-CD1 4.27Å; F75-I404 HydrophobicContact CD2-CD1 4Å; A80-I404 HydrophobicContact CB-CD1 3.61Å; A80-I404 HydrophobicContact CB-CG1 4Å; A81-I404 PolarHBondContact O-N 3.34Å; F82-I404 HydrophobicContact CD2-CB 4.11Å; F82-I404 HydrophobicContact CD2-CG2 3.73Å; F82-I404 HydrophobicContact CE2-CG2 3.94Å; I83-I404 PolarHBondContact N-O 2.75Å; H378-I404 HydrophobicContact CB-CG2 4Å
405I98.7Very high97.6Very high0 Ų026.6 Ų26.60%014%0.137CC..EExtended strand (participates in β ladder)trans-108.5111.7172.5-61.5160.2000107I83 A89 I92 L93 H378 L379 V403 A407 Y410 L442I83-I405 HydrophobicContact CB-CG1 4.1Å; I83-I405 HydrophobicContact CG1-CG1 3.86Å; A89-I405 HydrophobicContact CB-CD1 4.39Å; A89-I405 HydrophobicContact CB-CG1 4.39Å; A89-I405 HydrophobicContact CB-CG2 3.98Å; I92-I405 HydrophobicContact CG2-CD1 4.11Å; L93-I405 HydrophobicContact CD1-CD1 3.95Å; L93-I405 HydrophobicContact CD2-CD1 3.53Å; L93-I405 HydrophobicContact CG-CD1 3.59Å; H378-I405 CarbonylContact C-O 3.06Å; H378-I405 WeakPolarHBondContact CA-O 3.32Å; H378-I405 WeakPolarHBondContact CB-O 3.35Å; L379-I405 HydrophobicContact CB-CB 4.22Å; L379-I405 PolarHBondContact N-O 2.76Å; L379-I405 PolarHBondContact O-N 2.98Å; V403-I405 HydrophobicContact CG1-CG1 4.3Å; I405-A407 VanDerWaalsContact C-N 3.33Å; I405-A407 PolarHBondContact O-N 3.06Å; I405-Y410 HydrophobicContact CG2-CD2 4.44Å; I405-Y410 HydrophobicContact CG2-CE2 3.7Å; I405-L442 HydrophobicContact CG2-CD1 3.84Å
406P98Very high97.6Very high0 Ų027.9 Ų27.90%014%0.144CC..  trans-8274.7-170.935.8-38.4000111.6F56 Y60 F82 I83 C408 A409 Y410F56-P406 HydrophobicContact CB-CB 4.02Å; Y60-P406 HydrophobicContact CD2-CG 3.98Å; F82-P406 HydrophobicContact CE1-CB 4.16Å; F82-P406 HydrophobicContact CE1-CG 3.71Å; F82-P406 HydrophobicContact CE2-CB 3.83Å; F82-P406 HydrophobicContact CE2-CG 4.17Å; F82-P406 HydrophobicContact CZ-CB 3.4Å; F82-P406 VanDerWaalsContact CZ-CB 3.4Å; F82-P406 HydrophobicContact CZ-CG 3.49Å; F82-P406 VanDerWaalsContact CZ-CG 3.49Å; I83-P406 WeakPolarHBondContact O-CD 3.44Å; I83-P406 WeakPolarHBondContact O-CG 3.23Å; P406-C408 VanDerWaalsContact C-N 3.28Å; P406-C408 PolarHBondContact O-N 3.05Å; P406-A409 HydrophobicContact CB-CB 3.9Å; P406-A409 HydrophobicContact CG-CB 4.25Å; P406-A409 WeakPolarHBondContact O-CA 3.24Å; P406-A409 WeakPolarHBondContact O-CB 3.39Å; P406-A409 PolarHBondContact O-N 2.87Å; P406-Y410 HydrophobicContact CG-CD1 4.11Å; P406-Y410 HydrophobicContact CG-CE1 3.67Å; P406-Y410 PolarHBondContact O-N 2.87Å; P406-Y410 VanDerWaalsContact O-N 3.08Å
407A98.3Very high97.6Very high0 Ų025.8 Ų25.80%013%0.131CC..Hα-helixtrans-49.2-45.6-17900000113.2T374 P377 I405 A409 Y410 H411 L442T374-A407 HydrophobicContact CG2-CB 4.13Å; P377-A407 PolarHBondContact O-N 2.89Å; P377-A407 VanDerWaalsContact O-N 3.14Å; I405-A407 VanDerWaalsContact C-N 3.33Å; I405-A407 PolarHBondContact O-N 3.06Å; A407-A409 PolarHBondContact O-N 3.34Å; A407-Y410 PolarHBondContact O-N 3.37Å; A407-H411 WeakPolarHBondContact O-CB 3.29Å; A407-H411 PolarHBondContact O-CD2 2.83Å; A407-H411 PolarHBondContact O-N 2.87Å; A407-L442 HydrophobicContact CB-CB 3.83Å; A407-L442 HydrophobicContact CB-CD1 4.43Å
408C97.6Very high97.5Very high1 Ų129.6 Ų29.61%0.00716%0.155CC..Hα-helixtrans-61.7-30.2177.961.60000113.9H53 T374 P377 P406H53-C408 WeakPolarHBondContact CD2-CB 3.31Å; H53-C408 WeakPolarHBondContact NE2-CB 3.25Å; T374-C408 HydrophobicContact CG2-CB 4.3Å; P377-C408 HydrophobicContact CB-CB 4.04Å; P377-C408 PolarHBondContact O-N 2.98Å; P377-C408 PolarHBondContact O-SG 2.96Å; P406-C408 VanDerWaalsContact C-N 3.28Å; P406-C408 PolarHBondContact O-N 3.05Å
409A98.1Very high97.5Very high0 Ų032.6 Ų32.60%017%0.173CC..Hα-helixtrans-78.9-41.3178.600000111.2Y57 Y60 P406 A407 H411 R412 D413Y57-A409 HydrophobicContact CD2-CB 4.44Å; Y60-A409 VanDerWaalsContact CB-CB 3.46Å; Y60-A409 HydrophobicContact CD1-CB 3.65Å; Y60-A409 HydrophobicContact CD2-CB 4.3Å; Y60-A409 HydrophobicContact CE1-CB 4.48Å; Y60-A409 HydrophobicContact CG-CB 3.53Å; P406-A409 HydrophobicContact CB-CB 3.9Å; P406-A409 HydrophobicContact CG-CB 4.25Å; P406-A409 WeakPolarHBondContact O-CA 3.24Å; P406-A409 WeakPolarHBondContact O-CB 3.39Å; P406-A409 PolarHBondContact O-N 2.87Å; A407-A409 PolarHBondContact O-N 3.34Å; A409-H411 VanDerWaalsContact C-N 3.27Å; A409-H411 PolarHBondContact O-N 3.38Å; A409-R412 CarbonylContact O-C 3.32Å; A409-R412 PolarHBondContact O-N 3.42Å; A409-D413 PolarHBondContact O-N 2.87Å
410Y98.5Very high97.4Very high0 Ų026.7 Ų26.70%015%0.15CC..Hα-helixtrans-58.9-42.4173.7-66.40.9000110.8Y60 I83 D85 T86 A89 I405 P406 A407 R412 D413 Y417 L442Y60-Y410 HydrophobicContact CD2-CD1 4.32Å; Y60-Y410 HydrophobicContact CD2-CE1 4.06Å; Y60-Y410 AromaticContact CE2-CD1 3.74Å; Y60-Y410 HydrophobicContact CE2-CD1 3.74Å; Y60-Y410 AromaticContact CE2-CE1 3.47Å; Y60-Y410 HydrophobicContact CE2-CE1 3.47Å; Y60-Y410 VanDerWaalsContact CE2-CE1 3.47Å; Y60-Y410 AromaticContact CZ-CD1 3.86Å; I83-Y410 PolarHBondContact O-OH 3.34Å; D85-Y410 PolarHBondContact O-OH 2.86Å; T86-Y410 HydrophobicContact CG2-CD2 4.03Å; T86-Y410 HydrophobicContact CG2-CE2 3.92Å; T86-Y410 HydrophobicContact CG2-CG 4.38Å; A89-Y410 HydrophobicContact CB-CE2 3.98Å; I405-Y410 HydrophobicContact CG2-CD2 4.44Å; I405-Y410 HydrophobicContact CG2-CE2 3.7Å; P406-Y410 HydrophobicContact CG-CD1 4.11Å; P406-Y410 HydrophobicContact CG-CE1 3.67Å; P406-Y410 PolarHBondContact O-N 2.87Å; P406-Y410 VanDerWaalsContact O-N 3.08Å; A407-Y410 PolarHBondContact O-N 3.37Å; Y410-R412 PolarHBondContact O-N 2.85Å; Y410-R412 VanDerWaalsContact O-N 3.12Å; Y410-D413 WeakPolarHBondContact O-CB 3.42Å; Y410-D413 PolarHBondContact O-N 3.13Å; Y410-Y417 WeakPolarHBondContact O-CD2 3.19Å; Y410-Y417 WeakPolarHBondContact O-CE2 3.1Å; Y410-L442 HydrophobicContact CD2-CD1 3.99Å; Y410-L442 HydrophobicContact CE2-CD1 4.3Å
411H98.5Very high97.5Very high0 Ų030.4 Ų30.40%016%0.158CC..THydrogen-bonded Turntrans-64.6-16.5178.1-69-177.6000114.1R371 T374 A407 A409 Y417 E440 L442R371-H411 HydrophobicContact CG-CB 3.75Å; R371-H411 WeakPolarHBondContact CG-O 3.22Å; R371-H411 PolarHBondContact NH1-O 2.89Å; R371-H411 WeakPolarHBondContact O-CB 3.5Å; R371-H411 PolarHBondContact O-ND1 2.89Å; T374-H411 PolarHBondContact OG1-ND1 2.81Å; A407-H411 WeakPolarHBondContact O-CB 3.29Å; A407-H411 PolarHBondContact O-CD2 2.83Å; A407-H411 PolarHBondContact O-N 2.87Å; A409-H411 VanDerWaalsContact C-N 3.27Å; A409-H411 PolarHBondContact O-N 3.38Å; H411-Y417 WeakPolarHBondContact O-CD2 3.29Å; H411-E440 PolarHBondContact CD2-O 2.78Å; H411-L442 PolarHBondContact NE2-N 3.45Å
412R97.6Very high97.5Very high37 Ų3733.8 Ų33.814%0.1418%0.179CC..THydrogen-bonded Turntrans-118.514.4179.6-66.5178.6174.2-103.5-1.9112.5Y57 L372 A409 Y410 E414 P420 E421Y57-R412 HydrophobicContact CD2-CB 4.03Å; Y57-R412 HydrophobicContact CE2-CB 3.53Å; L372-R412 PolarHBondContact O-NH2 2.91Å; A409-R412 CarbonylContact O-C 3.32Å; A409-R412 PolarHBondContact O-N 3.42Å; Y410-R412 PolarHBondContact O-N 2.85Å; Y410-R412 VanDerWaalsContact O-N 3.12Å; R412-E414 PolarHBondContact O-N 3.32Å; R412-P420 HydrophobicContact CB-CB 4.38Å; R412-P420 WeakPolarHBondContact O-CB 3.39Å; R412-P420 WeakPolarHBondContact O-CG 3.45Å; R412-E421 IonicContact CZ-OE1 4Å; R412-E421 IonicContact CZ-OE2 3.55Å; R412-E421 IonicContact NH1-OE1 2.81Å; R412-E421 PolarHBondContact NH1-OE1 3.47Å; R412-E421 IonicContact NH1-OE2 2.63Å; R412-E421 PolarHBondContact NH1-OE2 2.95Å
413D97.8Very high97.6Very high6 Ų634 Ų343%0.03218%0.18CC..  trans-74.2119.8174-171.4-29.4000109.4Y60 R64 A409 Y410 D415 L416 Y417Y60-D413 HydrophobicContact CE1-CB 4.15Å; Y60-D413 WeakPolarHBondContact CE1-OD2 3.35Å; Y60-D413 PolarHBondContact OH-OD2 3.22Å; R64-D413 IonicContact CZ-OD1 2.67Å; R64-D413 IonicContact NH1-OD1 2.62Å; R64-D413 PolarHBondContact NH1-OD1 2.77Å; R64-D413 IonicContact NH1-OD2 3.83Å; R64-D413 IonicContact NH2-OD1 3.85Å; A409-D413 PolarHBondContact O-N 2.87Å; Y410-D413 WeakPolarHBondContact O-CB 3.42Å; Y410-D413 PolarHBondContact O-N 3.13Å; D413-D415 PolarHBondContact O-N 2.61Å; D413-D415 WeakPolarHBondContact OD1-CA 3.37Å; D413-D415 VanDerWaalsContact OD1-CB 3.3Å; D413-D415 WeakPolarHBondContact OD1-CB 3.26Å; D413-D415 PolarHBondContact OD1-N 2.66Å; D413-L416 HydrophobicContact CB-CB 4.15Å; D413-L416 HydrophobicContact CB-CD1 3.98Å; D413-L416 HydrophobicContact CB-CG 3.94Å; D413-L416 PolarHBondContact O-N 3.03Å; D413-L416 VanDerWaalsContact O-N 3.16Å; D413-Y417 WeakPolarHBondContact O-CA 3.14Å; D413-Y417 PolarHBondContact O-N 3.37Å
414E97.1Very high97.6Very high100 Ų10036.3 Ų36.347%0.46719%0.192SC..THydrogen-bonded Turntrans-62.1-25.6177.173-168.3165.400114.5R64 K65 R412 Y417 P418 P420R64-E414 IonicContact CZ-OE1 3.13Å; R64-E414 IonicContact NH2-OE1 3.62Å; R64-E414 PolarHBondContact NH2-OE1 3.47Å; K65-E414 IonicContact NZ-OE1 3.72Å; R412-E414 PolarHBondContact O-N 3.32Å; E414-Y417 CarbonylContact O-C 3.47Å; E414-P418 WeakPolarHBondContact O-CA 3.48Å; E414-P420 HydrophobicContact CB-CG 4.29Å
415D95.7Very high97.7Very high107 Ų10736.4 Ų36.457%0.57219%0.193SC*.THydrogen-bonded Turntrans-76-27.4178-60.7-38.5000110.6R64 D413R64-D415 IonicContact CZ-OD2 2.72Å; R64-D415 IonicContact NE-OD2 3.84Å; R64-D415 IonicContact NH1-OD2 2.66Å; R64-D415 IonicContact NH2-OD1 3.75Å; R64-D415 IonicContact NH2-OD2 3.24Å; R64-D415 PolarHBondContact NH2-OD2 2.75Å; D413-D415 PolarHBondContact O-N 2.61Å; D413-D415 WeakPolarHBondContact OD1-CA 3.37Å; D413-D415 VanDerWaalsContact OD1-CB 3.3Å; D413-D415 WeakPolarHBondContact OD1-CB 3.26Å; D413-D415 PolarHBondContact OD1-N 2.66Å
416L96.6Very high97.6Very high42 Ų4239.3 Ų39.322%0.2221%0.206CC..THydrogen-bonded Turntrans-93.3-35.9174.9-56.5-179.3000112.2T86 D413 E440T86-L416 HydrophobicContact CG2-CD1 4.09Å; D413-L416 HydrophobicContact CB-CB 4.15Å; D413-L416 HydrophobicContact CB-CD1 3.98Å; D413-L416 HydrophobicContact CB-CG 3.94Å; D413-L416 PolarHBondContact O-N 3.03Å; D413-L416 VanDerWaalsContact O-N 3.16Å; L416-E440 HydrophobicContact CD1-CB 4.25Å; L416-E440 HydrophobicContact CD1-CG 4.11Å; L416-E440 HydrophobicContact CD2-CG 4.12Å
417Y97.4Very high97.6Very high2 Ų240.2 Ų40.21%0.00821%0.21CC..SBendtrans-134.988.5-174.9-61.3-77.1000110.2R371 Y410 H411 D413 E414 N419 P420 R436 E440R371-Y417 VanDerWaalsContact CD-CD1 3.46Å; R371-Y417 VanDerWaalsContact CD-CE1 3.5Å; R371-Y417 HydrophobicContact CG-CE1 4.39Å; R371-Y417 HydrophobicContact CG-CE2 4.46Å; Y410-Y417 WeakPolarHBondContact O-CD2 3.19Å; Y410-Y417 WeakPolarHBondContact O-CE2 3.1Å; H411-Y417 WeakPolarHBondContact O-CD2 3.29Å; D413-Y417 WeakPolarHBondContact O-CA 3.14Å; D413-Y417 PolarHBondContact O-N 3.37Å; E414-Y417 CarbonylContact O-C 3.47Å; Y417-N419 PolarHBondContact O-N 3.09Å; Y417-P420 WeakPolarHBondContact O-CA 3.32Å; Y417-P420 WeakPolarHBondContact O-CB 3.46Å; Y417-P420 VanDerWaalsContact O-CD 3.28Å; Y417-P420 WeakPolarHBondContact O-CD 3.16Å; Y417-R436 PolarHBondContact OH-NE 3.24Å; Y417-E440 PolarHBondContact OH-O 3.01Å; Y417-E440 VanDerWaalsContact OH-O 3.09Å
418P96.6Very high97.6Very high80 Ų8040.8 Ų40.852%0.51921%0.212SC..SBendtrans-57.7134.3-179.7-26.634.7000111.9E414 R427E414-P418 WeakPolarHBondContact O-CA 3.48Å; P418-R427 PolarHBondContact O-NH1 3.02Å; P418-R427 PolarHBondContact O-NH2 2.98Å
419N97.4Very high97.6Very high121 Ų12141.4 Ų41.465%0.64722%0.216SC*.SBendtrans55.160.8-168.8-53.3-54.9000112.3Y417 E421 T422 R427Y417-N419 PolarHBondContact O-N 3.09Å; N419-E421 PolarHBondContact O-N 3.1Å; N419-T422 PolarHBondContact O-N 3.38Å; N419-T422 VanDerWaalsContact O-N 3.08Å; N419-R427 PolarHBondContact O-NH2 3.37Å
420P97.3Very high97.6Very high17 Ų1744.4 Ų44.411%0.1124%0.236CC..THydrogen-bonded Turntrans-65.4-16.8-166.724.6-33.6000114.2R371 L372 R412 E414 Y417R371-P420 VanDerWaalsContact CZ-O 3.26Å; R371-P420 PolarHBondContact NH1-O 2.89Å; R371-P420 PolarHBondContact NH2-O 2.89Å; L372-P420 WeakPolarHBondContact CD2-O 3.45Å; R412-P420 HydrophobicContact CB-CB 4.38Å; R412-P420 WeakPolarHBondContact O-CB 3.39Å; R412-P420 WeakPolarHBondContact O-CG 3.45Å; E414-P420 HydrophobicContact CB-CG 4.29Å; Y417-P420 WeakPolarHBondContact O-CA 3.32Å; Y417-P420 WeakPolarHBondContact O-CB 3.46Å; Y417-P420 VanDerWaalsContact O-CD 3.28Å; Y417-P420 WeakPolarHBondContact O-CD 3.16Å
421E96.4Very high97.5Very high110 Ų11050.6 Ų50.651%0.51427%0.265SS..THydrogen-bonded Turntrans-85-15.5178.7-61.3-57.9133.800113.4R412 N419R412-E421 IonicContact CZ-OE1 4Å; R412-E421 IonicContact CZ-OE2 3.55Å; R412-E421 IonicContact NH1-OE1 2.81Å; R412-E421 PolarHBondContact NH1-OE1 3.47Å; R412-E421 IonicContact NH1-OE2 2.63Å; R412-E421 PolarHBondContact NH1-OE2 2.95Å; N419-E421 PolarHBondContact O-N 3.1Å
422T97.8Very high97.4Very high80 Ų8055.1 Ų55.149%0.49129%0.285SS..SBendtrans-79.2129.8178.6-56.40000110.7E368 R371 N419 D424E368-T422 VanDerWaalsContact OE1-O 3.06Å; R371-T422 PolarHBondContact NH2-O 3.46Å; N419-T422 PolarHBondContact O-N 3.38Å; N419-T422 VanDerWaalsContact O-N 3.08Å; T422-D424 PolarHBondContact O-N 3.35Å
423F98.6Very high97.4Very high11 Ų1156.4 Ų56.45%0.04830%0.297CS..  trans-73.799.4170.4-172.8-109.1000110.4E325 I332 V365 E368 L372 P425E325-F423 HydrophobicContact CB-CD1 3.94Å; E325-F423 HydrophobicContact CB-CD2 3.98Å; E325-F423 HydrophobicContact CB-CE1 3.86Å; E325-F423 HydrophobicContact CB-CE2 3.89Å; E325-F423 HydrophobicContact CB-CG 3.99Å; E325-F423 HydrophobicContact CB-CZ 3.83Å; E325-F423 HydrophobicContact CG-CD1 4.48Å; E325-F423 HydrophobicContact CG-CD2 3.71Å; E325-F423 HydrophobicContact CG-CE2 3.88Å; E325-F423 HydrophobicContact CG-CG 4.03Å; E325-F423 HydrophobicContact CG-CZ 4.34Å; I332-F423 HydrophobicContact CD1-CD1 3.76Å; I332-F423 HydrophobicContact CD1-CE1 4.18Å; I332-F423 HydrophobicContact CG2-CE1 4.19Å; V365-F423 HydrophobicContact CG1-CE1 4.46Å; V365-F423 HydrophobicContact CG1-CZ 3.96Å; E368-F423 HydrophobicContact CB-CD2 4.31Å; E368-F423 HydrophobicContact CB-CE2 3.94Å; E368-F423 HydrophobicContact CG-CD2 3.43Å; E368-F423 VanDerWaalsContact CG-CD2 3.43Å; E368-F423 HydrophobicContact CG-CE2 3.57Å; E368-F423 HydrophobicContact CG-CG 4.14Å; E368-F423 HydrophobicContact CG-CZ 4.36Å; L372-F423 HydrophobicContact CD1-CB 3.93Å; L372-F423 HydrophobicContact CD1-CD2 3.71Å; L372-F423 HydrophobicContact CD1-CG 4.32Å; F423-P425 HydrophobicContact CE1-CG 4.08Å
424D98.6Very high97.3Very high49 Ų4962.9 Ų62.926%0.26233%0.331SS..  trans-127.397.5-178.3175.218.8000111.2E368 T422 E426 R427E368-D424 VanDerWaalsContact CD-O 3.31Å; E368-D424 PolarHBondContact OE1-N 3.49Å; T422-D424 PolarHBondContact O-N 3.35Å; D424-E426 PolarHBondContact O-N 3.07Å; D424-E426 VanDerWaalsContact OD1-CB 3.23Å; D424-E426 WeakPolarHBondContact OD1-CB 3.25Å; D424-E426 PolarHBondContact OD1-N 2.74Å; D424-R427 HydrophobicContact CB-CG 4.15Å; D424-R427 WeakPolarHBondContact O-CB 3.19Å; D424-R427 VanDerWaalsContact O-CG 3.32Å; D424-R427 WeakPolarHBondContact O-CG 3.39Å; D424-R427 PolarHBondContact O-N 2.93Å
425P98.7Very high97.3Very high2 Ų262.4 Ų62.41%0.01334%0.344CS..G310 helixtrans-56.7-27.7175.5-2736.1000113.9I332 Y361 Q364 V365 F423 R427 F428I332-P425 HydrophobicContact CD1-CG 4.2Å; I332-P425 HydrophobicContact CG2-CG 3.9Å; Y361-P425 HydrophobicContact CE2-CB 3.86Å; Q364-P425 HydrophobicContact CB-CB 4Å; Q364-P425 WeakPolarHBondContact CB-O 3.36Å; V365-P425 HydrophobicContact CG2-CB 4.05Å; V365-P425 HydrophobicContact CG2-CG 3.84Å; F423-P425 HydrophobicContact CE1-CG 4.08Å; P425-R427 PolarHBondContact O-N 3.17Å; P425-F428 PolarHBondContact O-N 3.13Å
426E98.1Very high97.3Very high60 Ų6059.4 Ų59.428%0.2833%0.325SS..G310 helixtrans-65.7-13-178.9-64.4-62.6147.100112.7R335 D424 F428 S429 K432R335-E426 IonicContact CZ-OE1 3.92Å; R335-E426 IonicContact NH1-OE1 2.61Å; R335-E426 PolarHBondContact NH1-OE1 2.76Å; R335-E426 IonicContact NH2-OE1 2.91Å; R335-E426 PolarHBondContact NH2-OE1 3.36Å; D424-E426 PolarHBondContact O-N 3.07Å; D424-E426 VanDerWaalsContact OD1-CB 3.23Å; D424-E426 WeakPolarHBondContact OD1-CB 3.25Å; D424-E426 PolarHBondContact OD1-N 2.74Å; E426-F428 PolarHBondContact O-N 3.5Å; E426-S429 PolarHBondContact O-N 3.14Å; E426-K432 VanDerWaalsContact O-CD 3.28Å; E426-K432 WeakPolarHBondContact O-CD 3.32Å; E426-K432 WeakPolarHBondContact O-CE 3.21Å; E426-K432 PolarHBondContact O-NZ 3.01Å
427R97.9Very high97.3Very high20 Ų2061.2 Ų61.28%0.07533%0.332CS..G310 helixtrans-60.6-21.2168.2-65.3178.6-166.1-72.4-3.6112.6E368 P418 N419 D424 P425 R436E368-R427 IonicContact OE1-NE 3.08Å; E368-R427 WeakPolarHBondContact OE2-CD 3.24Å; P418-R427 PolarHBondContact O-NH1 3.02Å; P418-R427 PolarHBondContact O-NH2 2.98Å; N419-R427 PolarHBondContact O-NH2 3.37Å; D424-R427 HydrophobicContact CB-CG 4.15Å; D424-R427 WeakPolarHBondContact O-CB 3.19Å; D424-R427 VanDerWaalsContact O-CG 3.32Å; D424-R427 WeakPolarHBondContact O-CG 3.39Å; D424-R427 PolarHBondContact O-N 2.93Å; P425-R427 PolarHBondContact O-N 3.17Å; R427-R436 PolarHBondContact O-NH2 3.26Å
428F98.4Very high97.2Very high12 Ų1264 Ų645%0.05335%0.352CS..G310 helixtrans-110.620.7-177.1-69.5-87000112.9Q364 S367 E368 R371 P425 E426 V433 W441Q364-F428 HydrophobicContact CB-CB 4.19Å; Q364-F428 HydrophobicContact CG-CB 4.11Å; Q364-F428 WeakPolarHBondContact CG-O 3.03Å; S367-F428 VanDerWaalsContact CB-CG 3.46Å; E368-F428 HydrophobicContact CB-CD2 3.99Å; E368-F428 HydrophobicContact CB-CE2 4.11Å; E368-F428 VanDerWaalsContact OE2-CE2 3.24Å; E368-F428 WeakPolarHBondContact OE2-CE2 3.47Å; R371-F428 HydrophobicContact CB-CE2 4.19Å; R371-F428 HydrophobicContact CB-CZ 4.09Å; P425-F428 PolarHBondContact O-N 3.13Å; E426-F428 PolarHBondContact O-N 3.5Å; F428-V433 HydrophobicContact CB-CG2 4.28Å; F428-V433 HydrophobicContact CD1-CG2 4.04Å; F428-W441 AromaticContact CE1-CD1 3.47Å; F428-W441 VanDerWaalsContact CE1-CD1 3.47Å; F428-W441 AromaticContact CE1-CD2 3.9Å; F428-W441 HydrophobicContact CE1-CD2 3.9Å; F428-W441 AromaticContact CE1-CE2 3.59Å; F428-W441 AromaticContact CE1-CG 3.78Å; F428-W441 HydrophobicContact CE1-CG 3.78Å; F428-W441 HydrophobicContact CE1-CZ2 4.29Å; F428-W441 AromaticContact CE1-NE1 3.31Å; F428-W441 VanDerWaalsContact CE1-NE1 3.31Å; F428-W441 AromaticContact CZ-CD1 3.34Å; F428-W441 HydrophobicContact CZ-CD2 4.49Å; F428-W441 AromaticContact CZ-CE2 3.99Å; F428-W441 HydrophobicContact CZ-CG 4.09Å; F428-W441 AromaticContact CZ-NE1 3.22Å
429S97.7Very high97.2Very high13 Ų1360.2 Ų60.29%0.09133%0.328CS..  trans-53.6147.2166.293.10000110.3E426 E431 K432 V433E426-S429 PolarHBondContact O-N 3.14Å; S429-E431 WeakPolarHBondContact CB-OE2 3.43Å; S429-E431 PolarHBondContact O-N 2.94Å; S429-E431 VanDerWaalsContact O-N 3.14Å; S429-E431 PolarHBondContact OG-OE2 3.36Å; S429-K432 PolarHBondContact O-N 3.5Å; S429-K432 PolarHBondContact OG-N 3.42Å; S429-V433 WeakPolarHBondContact O-CG2 3.08Å; S429-V433 PolarHBondContact O-N 3.13Å
430P96.1Very high97.2Very high64 Ų6456.2 Ų56.242%0.41631%0.305SS..Hα-helixtrans-49.8-42.3-179-28.536.2000113V433 D434P430-V433 PolarHBondContact O-N 3.14Å; P430-D434 WeakPolarHBondContact O-CB 3.26Å; P430-D434 PolarHBondContact O-N 3Å
431E96.8Very high97.3Very high130 Ų13057.8 Ų57.861%0.60731%0.309SS*.Hα-helixtrans-65.5-42.3-178.9-52.372.7-156.500111.9S429 A435S429-E431 WeakPolarHBondContact CB-OE2 3.43Å; S429-E431 PolarHBondContact O-N 2.94Å; S429-E431 VanDerWaalsContact O-N 3.14Å; S429-E431 PolarHBondContact OG-OE2 3.36Å; E431-A435 WeakPolarHBondContact O-CB 3.42Å; E431-A435 PolarHBondContact O-N 2.84Å; E431-A435 VanDerWaalsContact O-N 3.09Å
432K97.1Very high97.4Very high95 Ų9552.7 Ų52.741%0.41329%0.285SS..Hα-helixtrans-72.4-30.5177.9-70.3-170.5-164.1156.40112.4E426 S429 R436E426-K432 VanDerWaalsContact O-CD 3.28Å; E426-K432 WeakPolarHBondContact O-CD 3.32Å; E426-K432 WeakPolarHBondContact O-CE 3.21Å; E426-K432 PolarHBondContact O-NZ 3.01Å; S429-K432 PolarHBondContact O-N 3.5Å; S429-K432 PolarHBondContact OG-N 3.42Å; K432-R436 WeakPolarHBondContact O-CB 3.39Å; K432-R436 PolarHBondContact O-N 3Å
433V96.9Very high97.4Very high64 Ų6450 Ų5039%0.38827%0.269SS..Hα-helixtrans-69.6-45.1174.2173.10000110.3F428 S429 P430 A435 R436F428-V433 HydrophobicContact CB-CG2 4.28Å; F428-V433 HydrophobicContact CD1-CG2 4.04Å; S429-V433 WeakPolarHBondContact O-CG2 3.08Å; S429-V433 PolarHBondContact O-N 3.13Å; P430-V433 PolarHBondContact O-N 3.14Å; V433-A435 VanDerWaalsContact C-N 3.3Å; V433-A435 PolarHBondContact O-N 3.22Å; V433-R436 PolarHBondContact O-N 3.07Å; V433-R436 VanDerWaalsContact O-N 3.14Å
434D96.4Very high97.3Very high142 Ų14251.3 Ų51.376%0.75927%0.274SS*.Hα-helixtrans-65.1-33.1179.5-75.7-9.4000112.7P430 R436P430-D434 WeakPolarHBondContact O-CB 3.26Å; P430-D434 PolarHBondContact O-N 3Å; D434-R436 VanDerWaalsContact C-N 3.32Å
435A96.3Very high97.3Very high90 Ų9049.6 Ų49.674%0.74427%0.268SS*.THydrogen-bonded Turntrans-78-13.3175.900000114E431 V433E431-A435 WeakPolarHBondContact O-CB 3.42Å; E431-A435 PolarHBondContact O-N 2.84Å; E431-A435 VanDerWaalsContact O-N 3.09Å; V433-A435 VanDerWaalsContact C-N 3.3Å; V433-A435 PolarHBondContact O-N 3.22Å
436R96Very high97.2Very high43 Ų4351 Ų5116%0.16228%0.276CS..SBendtrans-90.6141.5-175.1-169.8-172.6-68.9133.111.2111.3Y417 R427 K432 V433 D434 S438 E440Y417-R436 PolarHBondContact OH-NE 3.24Å; R427-R436 PolarHBondContact O-NH2 3.26Å; K432-R436 WeakPolarHBondContact O-CB 3.39Å; K432-R436 PolarHBondContact O-N 3Å; V433-R436 PolarHBondContact O-N 3.07Å; V433-R436 VanDerWaalsContact O-N 3.14Å; D434-R436 VanDerWaalsContact C-N 3.32Å; R436-S438 PolarHBondContact O-N 3.4Å; R436-E440 HydrophobicContact CG-CB 3.93Å; R436-E440 WeakPolarHBondContact CG-OE2 3.33Å
437E96.9Very high97.2Very high81 Ų8148.8 Ų48.838%0.37927%0.269SS..  trans-68.3132.3166.9-74.1-68.6179.900111.2K90 V439 E440K90-E437 WeakPolarHBondContact CE-OE2 3.36Å; K90-E437 IonicContact NZ-OE1 2.99Å; K90-E437 PolarHBondContact NZ-OE1 3.31Å; K90-E437 IonicContact NZ-OE2 2.66Å; K90-E437 PolarHBondContact NZ-OE2 3.45Å; E437-V439 HydrophobicContact CB-CG2 4.45Å; E437-V439 PolarHBondContact O-N 3.13Å; E437-E440 HydrophobicContact CB-CG 4.01Å; E437-E440 WeakPolarHBondContact O-CB 3.2Å; E437-E440 PolarHBondContact O-N 3.33Å
438S95.4Very high97.2Very high59 Ų5951 Ų5141%0.41329%0.286SS..G310 helixtrans-57.3-31.3-173.562.60000113.2R436 E440 W441 D446R436-S438 PolarHBondContact O-N 3.4Å; S438-E440 VanDerWaalsContact C-N 3.26Å; S438-E440 PolarHBondContact O-N 3.04Å; S438-W441 CarbonylContact O-C 3.31Å; S438-W441 PolarHBondContact O-N 2.64Å; S438-D446 WeakPolarHBondContact CB-OD2 3.39Å; S438-D446 PolarHBondContact OG-OD2 3.35Å
439V97.2Very high97.1Very high2 Ų250.6 Ų50.61%0.01228%0.284CS..G310 helixtrans-77.2-5.4179.8-640000115.2K90 L93 I94 E437 W441 L442 D446K90-V439 HydrophobicContact CB-CG1 4.03Å; K90-V439 HydrophobicContact CB-CG2 3.91Å; K90-V439 HydrophobicContact CG-CG1 4.33Å; L93-V439 HydrophobicContact CD1-CG1 4.11Å; I94-V439 HydrophobicContact CD1-CG1 4.23Å; E437-V439 HydrophobicContact CB-CG2 4.45Å; E437-V439 PolarHBondContact O-N 3.13Å; V439-W441 VanDerWaalsContact C-N 3.3Å; V439-L442 HydrophobicContact CB-CD2 4.32Å; V439-L442 HydrophobicContact CG1-CD2 4.43Å; V439-L442 WeakPolarHBondContact O-CD1 3.48Å; V439-L442 VanDerWaalsContact O-CG 3.23Å; V439-L442 WeakPolarHBondContact O-CG 3.31Å; V439-D446 HydrophobicContact CG1-CB 4.42Å
440E97.8Very high97.1Very high36 Ų3651.9 Ų51.917%0.16829%0.29CS..G310 helixtrans-80.2-19.2171.8-62.6173.517900110.9T86 H411 L416 Y417 R436 E437 S438T86-E440 HydrophobicContact CG2-CG 4.34Å; H411-E440 PolarHBondContact CD2-O 2.78Å; L416-E440 HydrophobicContact CD1-CB 4.25Å; L416-E440 HydrophobicContact CD1-CG 4.11Å; L416-E440 HydrophobicContact CD2-CG 4.12Å; Y417-E440 PolarHBondContact OH-O 3.01Å; Y417-E440 VanDerWaalsContact OH-O 3.09Å; R436-E440 HydrophobicContact CG-CB 3.93Å; R436-E440 WeakPolarHBondContact CG-OE2 3.33Å; E437-E440 HydrophobicContact CB-CG 4.01Å; E437-E440 WeakPolarHBondContact O-CB 3.2Å; E437-E440 PolarHBondContact O-N 3.33Å; S438-E440 VanDerWaalsContact C-N 3.26Å; S438-E440 PolarHBondContact O-N 3.04Å
441W98.3Very high97.2Very high51 Ų5151.4 Ų51.419%0.19329%0.288CS..  trans-125.696.2174.3-17174.4000111.7S367 L370 F428 S438 V439 P443 F444S367-W441 PolarHBondContact O-NE1 3.4Å; L370-W441 HydrophobicContact CB-CZ2 4.22Å; L370-W441 HydrophobicContact CD1-CZ2 4.26Å; F428-W441 AromaticContact CE1-CD1 3.47Å; F428-W441 VanDerWaalsContact CE1-CD1 3.47Å; F428-W441 AromaticContact CE1-CD2 3.9Å; F428-W441 HydrophobicContact CE1-CD2 3.9Å; F428-W441 AromaticContact CE1-CE2 3.59Å; F428-W441 AromaticContact CE1-CG 3.78Å; F428-W441 HydrophobicContact CE1-CG 3.78Å; F428-W441 HydrophobicContact CE1-CZ2 4.29Å; F428-W441 AromaticContact CE1-NE1 3.31Å; F428-W441 VanDerWaalsContact CE1-NE1 3.31Å; F428-W441 AromaticContact CZ-CD1 3.34Å; F428-W441 HydrophobicContact CZ-CD2 4.49Å; F428-W441 AromaticContact CZ-CE2 3.99Å; F428-W441 HydrophobicContact CZ-CG 4.09Å; F428-W441 AromaticContact CZ-NE1 3.22Å; S438-W441 CarbonylContact O-C 3.31Å; S438-W441 PolarHBondContact O-N 2.64Å; V439-W441 VanDerWaalsContact C-N 3.3Å; W441-P443 HydrophobicContact CD2-CG 3.64Å; W441-P443 HydrophobicContact CE3-CG 3.91Å; W441-P443 HydrophobicContact CG-CG 4.36Å; W441-P443 HydrophobicContact CH2-CG 3.58Å; W441-P443 HydrophobicContact CZ2-CG 3.27Å; W441-P443 HydrophobicContact CZ3-CG 3.87Å; W441-P443 WeakPolarHBondContact O-CD 3.28Å; W441-F444 HydrophobicContact CH2-CD2 4.2Å; W441-F444 HydrophobicContact CH2-CE2 4.16Å; W441-F444 HydrophobicContact CZ3-CD2 4.41Å
442L98.3Very high97.2Very high2 Ų246.4 Ų46.41%0.0127%0.265CS..  trans-111.630.4-170.9-67.3174.1000116.6L93 L379 I405 A407 Y410 H411 V439 F444 G445 D446L93-L442 HydrophobicContact CD1-CD1 4.29Å; L93-L442 HydrophobicContact CD1-CD2 3.86Å; L379-L442 HydrophobicContact CD1-CB 4.3Å; L379-L442 HydrophobicContact CD1-CD1 4.06Å; L379-L442 HydrophobicContact CD1-CD2 4.11Å; L379-L442 HydrophobicContact CD1-CG 4.41Å; I405-L442 HydrophobicContact CG2-CD1 3.84Å; A407-L442 HydrophobicContact CB-CB 3.83Å; A407-L442 HydrophobicContact CB-CD1 4.43Å; Y410-L442 HydrophobicContact CD2-CD1 3.99Å; Y410-L442 HydrophobicContact CE2-CD1 4.3Å; H411-L442 PolarHBondContact NE2-N 3.45Å; V439-L442 HydrophobicContact CB-CD2 4.32Å; V439-L442 HydrophobicContact CG1-CD2 4.43Å; V439-L442 WeakPolarHBondContact O-CD1 3.48Å; V439-L442 VanDerWaalsContact O-CG 3.23Å; V439-L442 WeakPolarHBondContact O-CG 3.31Å; L442-F444 PolarHBondContact O-N 2.79Å; L442-F444 VanDerWaalsContact O-N 3.14Å; L442-G445 PolarHBondContact O-N 3.18Å; L442-D446 HydrophobicContact CD2-CB 3.78Å
443P97.3Very high97.1Very high24 Ų2442.7 Ų42.716%0.15625%0.253CS..THydrogen-bonded Turntrans-66.6-20.6-178.228.1-33.1000113.6L370 W441L370-P443 HydrophobicContact CB-CB 3.77Å; L370-P443 HydrophobicContact CB-CG 3.99Å; L370-P443 HydrophobicContact CD1-CB 4.39Å; L370-P443 HydrophobicContact CD1-CG 4.4Å; L370-P443 HydrophobicContact CD2-CB 4.31Å; L370-P443 HydrophobicContact CG-CB 4.39Å; W441-P443 HydrophobicContact CD2-CG 3.64Å; W441-P443 HydrophobicContact CE3-CG 3.91Å; W441-P443 HydrophobicContact CG-CG 4.36Å; W441-P443 HydrophobicContact CH2-CG 3.58Å; W441-P443 HydrophobicContact CZ2-CG 3.27Å; W441-P443 HydrophobicContact CZ3-CG 3.87Å; W441-P443 WeakPolarHBondContact O-CD 3.28Å
444F97.8Very high97Very high38 Ų3842.2 Ų42.217%0.16725%0.248CC..THydrogen-bonded Turntrans-109.16.7173-63.1-73.6000112.8L370 W441 L442 C451 M454 Q458L370-F444 HydrophobicContact CD1-CE2 3.54Å; L370-F444 HydrophobicContact CD1-CZ 3.7Å; W441-F444 HydrophobicContact CH2-CD2 4.2Å; W441-F444 HydrophobicContact CH2-CE2 4.16Å; W441-F444 HydrophobicContact CZ3-CD2 4.41Å; L442-F444 PolarHBondContact O-N 2.79Å; L442-F444 VanDerWaalsContact O-N 3.14Å; F444-C451 HydrophobicContact CB-CB 3.87Å; F444-C451 HydrophobicContact CD1-CB 3.88Å; F444-C451 HydrophobicContact CG-CB 4.37Å; F444-C451 WeakPolarHBondContact O-CB 3.48Å; F444-C451 PolarHBondContact O-N 2.79Å; F444-M454 HydrophobicContact CB-CB 4.44Å; F444-M454 HydrophobicContact CB-CG 4.19Å; F444-M454 HydrophobicContact CB-SD 3.89Å; F444-M454 HydrophobicContact CD1-CB 3.9Å; F444-M454 HydrophobicContact CD1-CG 3.8Å; F444-M454 HydrophobicContact CD2-CG 3.76Å; F444-M454 HydrophobicContact CD2-SD 3.83Å; F444-M454 HydrophobicContact CE1-CB 4.34Å; F444-M454 HydrophobicContact CE1-CG 4.09Å; F444-M454 HydrophobicContact CE2-CG 4.05Å; F444-M454 HydrophobicContact CG-CB 4.09Å; F444-M454 HydrophobicContact CG-CG 3.63Å; F444-M454 HydrophobicContact CG-SD 3.84Å; F444-M454 HydrophobicContact CZ-CG 4.21Å; F444-Q458 HydrophobicContact CE2-CG 4.42Å; F444-Q458 HydrophobicContact CZ-CG 4.15Å
445G97.8Very high96.9Very high13 Ų1341.2 Ų41.213%0.13423%0.233CC..  trans59-173.5-163.900000113.2L442L442-G445 PolarHBondContact O-N 3.18Å
446D97.7Very high96.9Very high31 Ų3137.5 Ų37.517%0.16620%0.2CC..  trans-139.8169.3-178.3-152.4-12000112.1L93 I94 S438 V439 L442L93-D446 HydrophobicContact CD1-CB 4.2Å; I94-D446 WeakPolarHBondContact CD1-OD2 3.21Å; S438-D446 WeakPolarHBondContact CB-OD2 3.39Å; S438-D446 PolarHBondContact OG-OD2 3.35Å; V439-D446 HydrophobicContact CG1-CB 4.42Å; L442-D446 HydrophobicContact CD2-CB 3.78Å
447G97.4Very high96.8Very high14 Ų1436.1 Ų36.114%0.14420%0.199CC..SBendtrans72.5-168.1-179.600000114.2L93 R449 N450L93-G447 WeakPolarHBondContact O-CA 3.31Å; G447-R449 PolarHBondContact O-N 2.97Å; G447-N450 WeakPolarHBondContact O-CB 3.33Å; G447-N450 PolarHBondContact O-N 3.3Å
448P97.4Very high96.8Very high67 Ų6733.8 Ų33.844%0.43519%0.189SC..THydrogen-bonded Turntrans-59.8-17.4-173.7-26.736.1000115.4F97F97-P448 HydrophobicContact CB-CG 4.44Å; F97-P448 HydrophobicContact CD1-CB 3.91Å; F97-P448 HydrophobicContact CD1-CG 3.64Å; F97-P448 HydrophobicContact CD2-CG 4.35Å; F97-P448 HydrophobicContact CE1-CB 3.68Å; F97-P448 HydrophobicContact CE1-CG 3.98Å; F97-P448 HydrophobicContact CE2-CB 4.37Å; F97-P448 HydrophobicContact CG-CB 4.35Å; F97-P448 HydrophobicContact CG-CG 3.85Å; F97-P448 HydrophobicContact CZ-CB 3.94Å; F97-P448 HydrophobicContact CZ-CG 4.47Å
449R97Very high96.8Very high3 Ų331.3 Ų31.31%0.01117%0.171CC..THydrogen-bonded Turntrans-112.224-179.2-159.9159.3179.5165.3-4.4113.3F97 A101 D102 R103 L121 D122 W126 G447F97-R449 HydrophobicContact CE2-CB 3.62Å; F97-R449 HydrophobicContact CZ-CB 3.84Å; A101-R449 WeakPolarHBondContact O-CD 2.9Å; A101-R449 PolarHBondContact O-NH1 3.13Å; D102-R449 IonicContact OD1-NH1 3.92Å; R103-R449 PolarHBondContact NH2-O 2.71Å; L121-R449 PolarHBondContact O-NH1 3.46Å; L121-R449 PolarHBondContact O-NH2 3.21Å; D122-R449 IonicContact OD1-CZ 2.66Å; D122-R449 IonicContact OD1-NH1 2.65Å; D122-R449 PolarHBondContact OD1-NH1 3.32Å; D122-R449 VanDerWaalsContact OD1-NH1 3.13Å; D122-R449 IonicContact OD1-NH2 3.91Å; D122-R449 PolarHBondContact OD1-NH2 3.36Å; W126-R449 VanDerWaalsContact CD1-CZ 3.47Å; W126-R449 VanDerWaalsContact CE2-CD 3.44Å; W126-R449 HydrophobicContact CH2-CB 4.13Å; W126-R449 HydrophobicContact CH2-CG 4.34Å; W126-R449 HydrophobicContact CZ2-CB 3.59Å; W126-R449 HydrophobicContact CZ2-CG 3.46Å; W126-R449 VanDerWaalsContact CZ2-CG 3.46Å; G447-R449 PolarHBondContact O-N 2.97Å
450N97.5Very high96.7Very high41 Ų4131.2 Ų31.222%0.21917%0.17CC..SBendtrans-64.7174.7168.975.4-12000112.7R130 G447 I452R130-N450 PolarHBondContact NH1-O 3.22Å; R130-N450 PolarHBondContact NH2-O 3.01Å; R130-N450 PolarHBondContact NH2-OD1 3.48Å; G447-N450 WeakPolarHBondContact O-CB 3.33Å; G447-N450 PolarHBondContact O-N 3.3Å; N450-I452 PolarHBondContact O-N 2.76Å
451C97.7Very high96.7Very high53 Ų5329.7 Ų29.736%0.35816%0.163SC..  trans-60.6117.4177.5-175.90000111.4F444 G453 M454F444-C451 HydrophobicContact CB-CB 3.87Å; F444-C451 HydrophobicContact CD1-CB 3.88Å; F444-C451 HydrophobicContact CG-CB 4.37Å; F444-C451 WeakPolarHBondContact O-CB 3.48Å; F444-C451 PolarHBondContact O-N 2.79Å; C451-G453 VanDerWaalsContact C-N 3.26Å; C451-G453 PolarHBondContact O-N 3.16Å; C451-G453 PolarHBondContact SG-N 2.87Å; C451-M454 HydrophobicContact CB-CB 4.38Å
452I96.3Very high96.7Very high25 Ų2529.7 Ų29.713%0.12816%0.163CC..THydrogen-bonded Turntrans-67.3-30.9177.1-157.8176.3000112L118 L133 F137 F307 N450L118-I452 HydrophobicContact CD2-CB 4.34Å; L118-I452 HydrophobicContact CD2-CD1 3.87Å; L118-I452 HydrophobicContact CD2-CG2 4.04Å; L133-I452 HydrophobicContact CB-CD1 3.72Å; F137-I452 WeakPolarHBondContact CB-O 3.43Å; F137-I452 HydrophobicContact CD2-CD1 3.83Å; F137-I452 HydrophobicContact CD2-CG1 3.65Å; F137-I452 HydrophobicContact CD2-CG2 4.35Å; F137-I452 HydrophobicContact CE2-CD1 4.12Å; F137-I452 HydrophobicContact CE2-CG1 4.21Å; F137-I452 HydrophobicContact CE2-CG2 4.16Å; F137-I452 HydrophobicContact CG-CG1 4.28Å; F137-I452 WeakPolarHBondContact CG-O 3.31Å; F307-I452 HydrophobicContact CE1-CG2 3.64Å; F307-I452 HydrophobicContact CZ-CG2 3.93Å; N450-I452 PolarHBondContact O-N 2.76Å
453G95.2Very high96.6Very high17 Ų1729.6 Ų29.618%0.17516%0.163CC..THydrogen-bonded Turntrans-90.16.8-175.400000114.5C451 R455 F456 G457C451-G453 VanDerWaalsContact C-N 3.26Å; C451-G453 PolarHBondContact O-N 3.16Å; C451-G453 PolarHBondContact SG-N 2.87Å; G453-R455 VanDerWaalsContact C-N 3.32Å; G453-R455 PolarHBondContact O-N 3.45Å; G453-F456 PolarHBondContact O-N 3.38Å; G453-G457 PolarHBondContact O-N 2.65Å
454M96Very high96.7Very high55 Ų5528.4 Ų28.427%0.27116%0.155SC..Hα-helixtrans-49.2-50.5-173.9176.8176.87100112.6F444 C451 F456 G457 Q458F444-M454 HydrophobicContact CB-CB 4.44Å; F444-M454 HydrophobicContact CB-CG 4.19Å; F444-M454 HydrophobicContact CB-SD 3.89Å; F444-M454 HydrophobicContact CD1-CB 3.9Å; F444-M454 HydrophobicContact CD1-CG 3.8Å; F444-M454 HydrophobicContact CD2-CG 3.76Å; F444-M454 HydrophobicContact CD2-SD 3.83Å; F444-M454 HydrophobicContact CE1-CB 4.34Å; F444-M454 HydrophobicContact CE1-CG 4.09Å; F444-M454 HydrophobicContact CE2-CG 4.05Å; F444-M454 HydrophobicContact CG-CB 4.09Å; F444-M454 HydrophobicContact CG-CG 3.63Å; F444-M454 HydrophobicContact CG-SD 3.84Å; F444-M454 HydrophobicContact CZ-CG 4.21Å; C451-M454 HydrophobicContact CB-CB 4.38Å; M454-F456 VanDerWaalsContact C-N 3.35Å; M454-F456 PolarHBondContact O-N 2.66Å; M454-G457 PolarHBondContact O-N 2.68Å; M454-Q458 WeakPolarHBondContact O-CB 3.34Å; M454-Q458 WeakPolarHBondContact O-CG 3.48Å; M454-Q458 PolarHBondContact O-N 2.73Å
455R94.6Very high96.7Very high121 Ų12126.6 Ų26.646%0.45715%0.148SC..Hα-helixtrans-63.7-39.4-179.4-66.6178.2178.1155.7-4.1112.7F137 M142 G453 M459F137-R455 PolarHBondContact O-NH1 2.9Å; M142-R455 HydrophobicContact CG-CB 3.99Å; M142-R455 HydrophobicContact SD-CB 4.07Å; G453-R455 VanDerWaalsContact C-N 3.32Å; G453-R455 PolarHBondContact O-N 3.45Å; R455-M459 VanDerWaalsContact O-CB 3.31Å; R455-M459 WeakPolarHBondContact O-CB 3.27Å; R455-M459 PolarHBondContact O-N 3.33Å
456F94.5Very high96.7Very high11 Ų1126 Ų265%0.04814%0.142CC..Hα-helixtrans-68.7-45.3178.7-178.3-96.5000111.3F137 M142 M145 V186 I187 C190 G453 M454 M459 Q460F137-F456 HydrophobicContact CD1-CB 4.29Å; F137-F456 HydrophobicContact CE1-CB 4.32Å; M142-F456 HydrophobicContact CE-CB 4.46Å; M142-F456 HydrophobicContact SD-CB 3.82Å; M142-F456 HydrophobicContact SD-CD2 4.25Å; M145-F456 HydrophobicContact CE-CD2 3.96Å; M145-F456 HydrophobicContact CE-CE2 4.29Å; M145-F456 HydrophobicContact SD-CD2 4.45Å; M145-F456 HydrophobicContact SD-CE2 4.2Å; V186-F456 HydrophobicContact CG1-CE1 4.36Å; V186-F456 HydrophobicContact CG1-CZ 3.75Å; I187-F456 HydrophobicContact CD1-CE1 3.73Å; I187-F456 HydrophobicContact CD1-CZ 4.08Å; C190-F456 HydrophobicContact CB-CE2 4.03Å; C190-F456 HydrophobicContact CB-CZ 4.1Å; G453-F456 PolarHBondContact O-N 3.38Å; M454-F456 VanDerWaalsContact C-N 3.35Å; M454-F456 PolarHBondContact O-N 2.66Å; F456-M459 HydrophobicContact CD2-CE 3.68Å; F456-M459 HydrophobicContact CE2-CE 4.03Å; F456-M459 PolarHBondContact O-N 3.08Å; F456-Q460 PolarHBondContact O-N 3.49Å; F456-Q460 VanDerWaalsContact O-N 3.09Å
457G95.5Very high96.6Very high14 Ų1424.9 Ų24.914%0.14414%0.135CC..Hα-helixtrans-58.3-47.8174.800000112.3G453 M454 M459 Q460 A461G453-G457 PolarHBondContact O-N 2.65Å; M454-G457 PolarHBondContact O-N 2.68Å; G457-M459 PolarHBondContact O-N 3.28Å; G457-Q460 WeakPolarHBondContact O-CG 3.45Å; G457-A461 VanDerWaalsContact O-CB 3.29Å; G457-A461 WeakPolarHBondContact O-CB 3.46Å; G457-A461 PolarHBondContact O-N 2.8Å
458Q96.1Very high96.6Very high32 Ų3224.5 Ų24.515%0.1513%0.13CC..Hα-helixtrans-61.8-42.2175.7-74.1176.7-29.200112.4F444 M454 A461 R462F444-Q458 HydrophobicContact CE2-CG 4.42Å; F444-Q458 HydrophobicContact CZ-CG 4.15Å; M454-Q458 WeakPolarHBondContact O-CB 3.34Å; M454-Q458 WeakPolarHBondContact O-CG 3.48Å; M454-Q458 PolarHBondContact O-N 2.73Å; Q458-A461 PolarHBondContact O-N 3.02Å; Q458-R462 WeakPolarHBondContact O-CB 3.44Å; Q458-R462 WeakPolarHBondContact O-CD 3.35Å; Q458-R462 WeakPolarHBondContact O-CG 3.42Å; Q458-R462 PolarHBondContact O-N 2.66Å
459M95.5Very high96.6Very high8 Ų821.3 Ų21.34%0.03911%0.109CC..Hα-helixtrans-59.8-52.7179.2178.9177.861.500111.8M142 F146 V149 R455 F456 G457 A461 R462 I463M142-M459 HydrophobicContact CB-SD 4.24Å; M142-M459 HydrophobicContact SD-CE 4.1Å; F146-M459 HydrophobicContact CB-SD 4.23Å; F146-M459 HydrophobicContact CD2-CG 4.12Å; F146-M459 HydrophobicContact CD2-SD 3.86Å; V149-M459 HydrophobicContact CG2-CE 3.93Å; R455-M459 VanDerWaalsContact O-CB 3.31Å; R455-M459 WeakPolarHBondContact O-CB 3.27Å; R455-M459 PolarHBondContact O-N 3.33Å; F456-M459 HydrophobicContact CD2-CE 3.68Å; F456-M459 HydrophobicContact CE2-CE 4.03Å; F456-M459 PolarHBondContact O-N 3.08Å; G457-M459 PolarHBondContact O-N 3.28Å; M459-A461 VanDerWaalsContact C-N 3.34Å; M459-A461 PolarHBondContact O-N 3.28Å; M459-R462 PolarHBondContact O-N 2.77Å; M459-I463 HydrophobicContact CG-CD1 3.84Å; M459-I463 WeakPolarHBondContact O-CD1 3.49Å; M459-I463 VanDerWaalsContact O-CG1 3.3Å; M459-I463 WeakPolarHBondContact O-CG1 3.36Å; M459-I463 PolarHBondContact O-N 3.13Å
460Q95.2Very high96.6Very high0 Ų021.9 Ų21.90%011%0.114CC..Hα-helixtrans-66.6-3618067.2177.4-51.800112.2V149 T183 V186 G311 S315 F456 G457 G464V149-Q460 HydrophobicContact CG1-CB 4.32Å; T183-Q460 VanDerWaalsContact CG2-OE1 3.3Å; V186-Q460 HydrophobicContact CG1-CB 4.13Å; G311-Q460 PolarHBondContact O-NE2 3.37Å; S315-Q460 PolarHBondContact OG-NE2 2.91Å; F456-Q460 PolarHBondContact O-N 3.49Å; F456-Q460 VanDerWaalsContact O-N 3.09Å; G457-Q460 WeakPolarHBondContact O-CG 3.45Å; Q460-G464 PolarHBondContact O-N 2.77Å
461A97.5Very high96.4Very high3 Ų324.4 Ų24.43%0.02512%0.12CC..Hα-helixtrans-64.8-46177.300000112M319 G457 Q458 M459 G464 L465M319-A461 HydrophobicContact CG-CB 3.99Å; M319-A461 HydrophobicContact SD-CB 4.49Å; G457-A461 VanDerWaalsContact O-CB 3.29Å; G457-A461 WeakPolarHBondContact O-CB 3.46Å; G457-A461 PolarHBondContact O-N 2.8Å; Q458-A461 PolarHBondContact O-N 3.02Å; M459-A461 VanDerWaalsContact C-N 3.34Å; M459-A461 PolarHBondContact O-N 3.28Å; A461-G464 PolarHBondContact O-N 2.9Å; A461-L465 WeakPolarHBondContact O-CB 3.34Å; A461-L465 WeakPolarHBondContact O-CD1 3.09Å; A461-L465 VanDerWaalsContact O-CG 3.26Å; A461-L465 WeakPolarHBondContact O-CG 3.26Å; A461-L465 PolarHBondContact O-N 3.17Å
462R97.9Very high96.3Very high51 Ų5122 Ų2219%0.19210%0.103CC..Hα-helixtrans-60.5-47.8176.5-70.9163.6-175.5165-5.9111.6I356 L362 N363 I366 Q458 M459 A466I356-R462 HydrophobicContact CD1-CB 4.35Å; I356-R462 HydrophobicContact CG2-CB 3.7Å; I356-R462 HydrophobicContact CG2-CG 4.23Å; L362-R462 HydrophobicContact CD2-CB 3.93Å; L362-R462 HydrophobicContact CD2-CG 4.15Å; L362-R462 HydrophobicContact CG-CG 4.43Å; N363-R462 PolarHBondContact OD1-NE 3.01Å; N363-R462 PolarHBondContact OD1-NH2 3.12Å; I366-R462 HydrophobicContact CD1-CB 4.4Å; I366-R462 HydrophobicContact CD1-CG 3.59Å; Q458-R462 WeakPolarHBondContact O-CB 3.44Å; Q458-R462 WeakPolarHBondContact O-CD 3.35Å; Q458-R462 WeakPolarHBondContact O-CG 3.42Å; Q458-R462 PolarHBondContact O-N 2.66Å; M459-R462 PolarHBondContact O-N 2.77Å; R462-A466 WeakPolarHBondContact O-CB 3.48Å; R462-A466 PolarHBondContact O-N 3.32Å
463I97.6Very high96.4Very high0 Ų024.1 Ų24.10%011%0.11CC..Hα-helixtrans-62.2-49.8179.5-68.2164.4000110.4F146 V149 I150 I356 M459 L465 A466 Q467F146-I463 HydrophobicContact CD2-CD1 3.89Å; F146-I463 HydrophobicContact CE2-CD1 3.58Å; F146-I463 HydrophobicContact CE2-CG1 4.1Å; F146-I463 HydrophobicContact CZ-CD1 4.2Å; V149-I463 HydrophobicContact CB-CD1 3.96Å; V149-I463 HydrophobicContact CG1-CB 4.41Å; V149-I463 HydrophobicContact CG1-CD1 3.51Å; V149-I463 HydrophobicContact CG1-CG2 4.31Å; I150-I463 HydrophobicContact CD1-CD1 4.18Å; I150-I463 HydrophobicContact CD1-CG1 4.29Å; I150-I463 HydrophobicContact CD1-CG2 3.99Å; I356-I463 HydrophobicContact CD1-CG1 4.01Å; I356-I463 HydrophobicContact CG1-CG1 4.08Å; M459-I463 HydrophobicContact CG-CD1 3.84Å; M459-I463 WeakPolarHBondContact O-CD1 3.49Å; M459-I463 VanDerWaalsContact O-CG1 3.3Å; M459-I463 WeakPolarHBondContact O-CG1 3.36Å; M459-I463 PolarHBondContact O-N 3.13Å; I463-L465 PolarHBondContact O-N 3.23Å; I463-A466 PolarHBondContact O-N 3.4Å; I463-Q467 HydrophobicContact CG2-CG 4.3Å; I463-Q467 WeakPolarHBondContact O-CB 3.39Å; I463-Q467 WeakPolarHBondContact O-CG 3.5Å; I463-Q467 PolarHBondContact O-N 3.49Å
464G97.6Very high96.5Very high0 Ų023.3 Ų23.30%010%0.102CC..Hα-helixtrans-59.4-46.1-179.600000112.6Q460 A461 I468Q460-G464 PolarHBondContact O-N 2.77Å; A461-G464 PolarHBondContact O-N 2.9Å; G464-I468 WeakPolarHBondContact O-CG1 3.47Å; G464-I468 PolarHBondContact O-N 3.31Å
465L98.5Very high96.6Very high0 Ų021.8 Ų21.80%010%0.096CC..Hα-helixtrans-67.5-44.7178-71167.4000112.3M319 C322 L323 L362 I366 A461 I463 Q467 I468 I469M319-L465 HydrophobicContact CB-CD2 4.21Å; M319-L465 HydrophobicContact CB-CG 4.37Å; M319-L465 HydrophobicContact CG-CD1 4.29Å; M319-L465 HydrophobicContact CG-CD2 4.38Å; M319-L465 HydrophobicContact CG-CG 3.99Å; C322-L465 HydrophobicContact CB-CD1 4.08Å; C322-L465 HydrophobicContact CB-CD2 4.01Å; L323-L465 HydrophobicContact CD1-CD2 4.42Å; L323-L465 HydrophobicContact CD2-CD2 3.87Å; L323-L465 HydrophobicContact CG-CD2 3.8Å; L362-L465 HydrophobicContact CD1-CB 4.04Å; L362-L465 HydrophobicContact CD1-CD1 4.39Å; I366-L465 HydrophobicContact CD1-CD1 3.82Å; I366-L465 HydrophobicContact CG1-CD1 3.59Å; A461-L465 WeakPolarHBondContact O-CB 3.34Å; A461-L465 WeakPolarHBondContact O-CD1 3.09Å; A461-L465 VanDerWaalsContact O-CG 3.26Å; A461-L465 WeakPolarHBondContact O-CG 3.26Å; A461-L465 PolarHBondContact O-N 3.17Å; I463-L465 PolarHBondContact O-N 3.23Å; L465-Q467 VanDerWaalsContact C-N 3.29Å; L465-Q467 PolarHBondContact O-N 3.38Å; L465-I468 PolarHBondContact O-N 2.8Å; L465-I469 WeakPolarHBondContact O-CB 3.48Å; L465-I469 WeakPolarHBondContact O-CG1 3.3Å; L465-I469 PolarHBondContact O-N 3.31Å
466A97.8Very high96.7Very high1 Ų119 Ų191%0.0089%0.092CC..Hα-helixtrans-59.3-42.617800000111.4I340 L351 I356 M359 L362 R462 I463 I468 S470I340-A466 HydrophobicContact CD1-CB 4.47Å; I340-A466 HydrophobicContact CG2-CB 4.38Å; L351-A466 HydrophobicContact CD2-CB 4.23Å; I356-A466 HydrophobicContact CD1-CB 4.25Å; M359-A466 HydrophobicContact SD-CB 4.15Å; L362-A466 HydrophobicContact CD2-CB 4.26Å; R462-A466 WeakPolarHBondContact O-CB 3.48Å; R462-A466 PolarHBondContact O-N 3.32Å; I463-A466 PolarHBondContact O-N 3.4Å; A466-I468 VanDerWaalsContact C-N 3.34Å; A466-I468 PolarHBondContact O-N 3.47Å; A466-S470 VanDerWaalsContact O-CB 3.25Å; A466-S470 WeakPolarHBondContact O-CB 3.5Å; A466-S470 PolarHBondContact O-N 2.87Å; A466-S470 VanDerWaalsContact O-N 3.09Å; A466-S470 PolarHBondContact O-OG 3.35Å; A466-S470 VanDerWaalsContact O-OG 3.06Å
467Q96.1Very high96.8Very high7 Ų719.1 Ų19.13%0.03310%0.095CC..Hα-helixtrans-61.9-39.1177.8-72.4-75.628.600113.2S153 V157 L351 I463 L465 R471S153-Q467 PolarHBondContact OG-NE2 3.47Å; V157-Q467 HydrophobicContact CG2-CB 3.72Å; V157-Q467 HydrophobicContact CG2-CG 4.21Å; L351-Q467 HydrophobicContact CD1-CG 3.69Å; I463-Q467 HydrophobicContact CG2-CG 4.3Å; I463-Q467 WeakPolarHBondContact O-CB 3.39Å; I463-Q467 WeakPolarHBondContact O-CG 3.5Å; I463-Q467 PolarHBondContact O-N 3.49Å; L465-Q467 VanDerWaalsContact C-N 3.29Å; L465-Q467 PolarHBondContact O-N 3.38Å; Q467-R471 PolarHBondContact O-NH1 3.01Å
468I97.4Very high96.8Very high6 Ų626.5 Ų26.53%0.03113%0.131CC..Hα-helixtrans-73-56.7178.2-64.6166.8000110F156 I160 M179 L323 G464 L465 A466 S470 R471 F472 V474F156-I468 HydrophobicContact CE1-CD1 3.77Å; F156-I468 HydrophobicContact CE1-CG1 3.73Å; F156-I468 HydrophobicContact CZ-CD1 3.75Å; F156-I468 HydrophobicContact CZ-CG1 3.95Å; I160-I468 HydrophobicContact CD1-CG1 4.06Å; M179-I468 HydrophobicContact CE-CD1 3.59Å; M179-I468 HydrophobicContact SD-CD1 4.22Å; L323-I468 HydrophobicContact CD1-CD1 3.7Å; L323-I468 HydrophobicContact CD2-CD1 4.36Å; L323-I468 HydrophobicContact CD2-CG2 3.99Å; G464-I468 WeakPolarHBondContact O-CG1 3.47Å; G464-I468 PolarHBondContact O-N 3.31Å; L465-I468 PolarHBondContact O-N 2.8Å; A466-I468 VanDerWaalsContact C-N 3.34Å; A466-I468 PolarHBondContact O-N 3.47Å; I468-S470 VanDerWaalsContact C-N 3.26Å; I468-S470 PolarHBondContact O-N 3.32Å; I468-R471 PolarHBondContact O-N 2.96Å; I468-R471 VanDerWaalsContact O-N 3.11Å; I468-F472 HydrophobicContact CG2-CB 4.39Å; I468-F472 WeakPolarHBondContact O-CA 3.43Å; I468-F472 WeakPolarHBondContact O-CB 3.46Å; I468-F472 WeakPolarHBondContact O-CD2 3.3Å; I468-F472 PolarHBondContact O-N 2.97Å; I468-V474 HydrophobicContact CG2-CG1 4.09Å
469I98Very high96.7Very high0 Ų029 Ų290%015%0.148CC..Hα-helixtrans-66.8-28.4-169.6-62.3-56000112.4L323 L326 Q333 L336 R337 I340 L465 R471 V474L323-I469 HydrophobicContact CD2-CD1 3.91Å; L326-I469 HydrophobicContact CD1-CD1 3.83Å; L326-I469 HydrophobicContact CD1-CG1 4.1Å; Q333-I469 HydrophobicContact CG-CD1 4.07Å; L336-I469 HydrophobicContact CD2-CG1 4.28Å; L336-I469 HydrophobicContact CD2-CG2 4.28Å; L336-I469 HydrophobicContact CG-CG2 4.18Å; R337-I469 HydrophobicContact CB-CG2 3.85Å; R337-I469 PolarHBondContact NE-O 2.86Å; I340-I469 HydrophobicContact CD1-CB 3.94Å; I340-I469 HydrophobicContact CD1-CG2 3.88Å; L465-I469 WeakPolarHBondContact O-CB 3.48Å; L465-I469 WeakPolarHBondContact O-CG1 3.3Å; L465-I469 PolarHBondContact O-N 3.31Å; I469-R471 VanDerWaalsContact C-N 3.3Å; I469-R471 PolarHBondContact O-N 3.49Å; I469-V474 HydrophobicContact CD1-CG2 4.25Å
470S95.4Very high96.8Very high15 Ų1529.4 Ų29.411%0.10515%0.151CC..THydrogen-bonded Turntrans-74.2-17.3177.375.10000114.5A466 I468A466-S470 VanDerWaalsContact O-CB 3.25Å; A466-S470 WeakPolarHBondContact O-CB 3.5Å; A466-S470 PolarHBondContact O-N 2.87Å; A466-S470 VanDerWaalsContact O-N 3.09Å; A466-S470 PolarHBondContact O-OG 3.35Å; A466-S470 VanDerWaalsContact O-OG 3.06Å; I468-S470 VanDerWaalsContact C-N 3.26Å; I468-S470 PolarHBondContact O-N 3.32Å
471R94.1Very high96.9Very high93 Ų9333.4 Ų33.435%0.35117%0.17SC..THydrogen-bonded Turntrans-125.3-17.6-172.3-72.1174.2-174.977.9-4.1114.3Q467 I468 I469 I506Q467-R471 PolarHBondContact O-NH1 3.01Å; I468-R471 PolarHBondContact O-N 2.96Å; I468-R471 VanDerWaalsContact O-N 3.11Å; I469-R471 VanDerWaalsContact C-N 3.3Å; I469-R471 PolarHBondContact O-N 3.49Å; R471-I506 VanDerWaalsContact C-CG1 3.41Å; R471-I506 VanDerWaalsContact O-CG1 3.28Å; R471-I506 WeakPolarHBondContact O-CG1 3.47Å; R471-I506 PolarHBondContact O-N 3.48Å
472F96.6Very high96.8Very high2 Ų237.4 Ų37.41%0.00919%0.19CC..EExtended strand (participates in β ladder)trans-133.9148.1-175.9-54.2-87.6000110.5V157 I160 V164 R337 I468 V503 E504 R505V157-F472 HydrophobicContact CG1-CE2 4.48Å; I160-F472 HydrophobicContact CB-CE1 4.47Å; I160-F472 HydrophobicContact CB-CE2 4.22Å; I160-F472 HydrophobicContact CB-CZ 3.9Å; I160-F472 HydrophobicContact CD1-CE2 4.46Å; I160-F472 HydrophobicContact CG2-CD1 4.11Å; I160-F472 HydrophobicContact CG2-CD2 4.34Å; I160-F472 HydrophobicContact CG2-CE1 3.59Å; I160-F472 HydrophobicContact CG2-CE2 3.88Å; I160-F472 HydrophobicContact CG2-CG 4.46Å; I160-F472 HydrophobicContact CG2-CZ 3.47Å; I160-F472 VanDerWaalsContact CG2-CZ 3.47Å; V164-F472 HydrophobicContact CB-CE1 4.44Å; R337-F472 PolarHBondContact NH2-O 2.85Å; I468-F472 HydrophobicContact CG2-CB 4.39Å; I468-F472 WeakPolarHBondContact O-CA 3.43Å; I468-F472 WeakPolarHBondContact O-CB 3.46Å; I468-F472 WeakPolarHBondContact O-CD2 3.3Å; I468-F472 PolarHBondContact O-N 2.97Å; F472-V503 HydrophobicContact CB-CG1 3.72Å; F472-V503 HydrophobicContact CD1-CG1 3.77Å; F472-V503 HydrophobicContact CG-CG1 3.9Å; F472-E504 CarbonylContact C-O 3.52Å; F472-E504 WeakPolarHBondContact CA-O 3.47Å; F472-E504 WeakPolarHBondContact CB-O 3.2Å; F472-R505 HydrophobicContact CD1-CG 4Å; F472-R505 HydrophobicContact CE1-CG 3.73Å
473R97.1Very high96.6Very high70 Ų7039.9 Ų39.926%0.26421%0.213SC..EExtended strand (participates in β ladder)trans-95.6133.3161.8-176.8176-69.8-89.2-1.3108.1D334 V503 E504 I506D334-R473 IonicContact OD1-CZ 3.75Å; D334-R473 IonicContact OD1-NH1 3.58Å; D334-R473 PolarHBondContact OD1-NH1 2.92Å; D334-R473 IonicContact OD1-NH2 3.78Å; D334-R473 PolarHBondContact OD1-NH2 3.33Å; D334-R473 IonicContact OD2-NH1 3.69Å; D334-R473 IonicContact OD2-NH2 3.74Å; R473-V503 WeakPolarHBondContact O-CA 3.42Å; R473-E504 HydrophobicContact CB-CB 4.47Å; R473-E504 PolarHBondContact N-O 3.27Å; R473-E504 PolarHBondContact O-N 2.77Å; R473-I506 HydrophobicContact CB-CG2 3.98Å
474V97.8Very high96.5Very high1 Ų140.7 Ų40.71%0.00622%0.217CC..EExtended strand (participates in β ladder)trans-109.2134.8172-61.20000109.7L323 L326 A327 Q330 Q333 I468 I469 R502 V503L323-V474 HydrophobicContact CD2-CG1 4.31Å; L323-V474 HydrophobicContact CD2-CG2 4.16Å; L326-V474 HydrophobicContact CB-CG2 4.43Å; A327-V474 HydrophobicContact CB-CG2 4.32Å; Q330-V474 PolarHBondContact NE2-O 3.39Å; Q333-V474 PolarHBondContact NE2-O 3.19Å; I468-V474 HydrophobicContact CG2-CG1 4.09Å; I469-V474 HydrophobicContact CD1-CG2 4.25Å; V474-R502 CarbonylContact C-O 3.53Å; V474-R502 VanDerWaalsContact CA-O 3.32Å; V474-R502 WeakPolarHBondContact CA-O 3.38Å; V474-V503 HydrophobicContact CG1-CG2 4.22Å
475S97.8Very high96.3Very high23 Ų2346.5 Ų46.516%0.16124%0.242CC..EExtended strand (participates in β ladder)trans-143.2161.6-17957.30000110.9R502S475-R502 PolarHBondContact N-O 3.03Å; S475-R502 PolarHBondContact O-N 3.14Å
476V97.8Very high96.1Very high61 Ų6149.5 Ų49.537%0.3725%0.254SS..  trans-67.2153.7174.6-58.40000110.4A327 Q328 T480 I482A327-V476 HydrophobicContact CB-CG1 4.27Å; Q328-V476 HydrophobicContact CG-CG1 3.64Å; V476-T480 HydrophobicContact CB-CG2 4.37Å; V476-T480 HydrophobicContact CG1-CG2 4.25Å; V476-I482 HydrophobicContact CB-CD1 4.27Å; V476-I482 HydrophobicContact CG1-CD1 3.77Å
477C95.6Very high95.8Very high15 Ų1550.6 Ų50.610%0.10126%0.262CS..  trans-138.3174.8176.267.30000110.5V172 T479 T480 R502V172-C477 HydrophobicContact CG2-CB 4.13Å; C477-T479 PolarHBondContact O-N 2.9Å; C477-T479 PolarHBondContact SG-OG1 3.38Å; C477-T480 PolarHBondContact N-OG1 2.86Å; C477-T480 VanDerWaalsContact O-CB 3.31Å; C477-T480 WeakPolarHBondContact O-CB 3.3Å; C477-T480 PolarHBondContact O-N 3.32Å; C477-T480 PolarHBondContact O-OG1 3.01Å; C477-T480 PolarHBondContact SG-OG1 2.85Å; C477-R502 HydrophobicContact CB-CB 4.13Å
478D95.3Very high95.5Very high169 Ų16951.7 Ų51.790%0.90427%0.269SS*.THydrogen-bonded Turntrans-60.1-21.6-175.7-55.8-25.1000113.8
479T95.3Very high94.8Very high83 Ų8354.6 Ų54.651%0.50929%0.287SS..THydrogen-bonded Turntrans-96.6-1.3176.857.10000113.7C477 E481 Y500C477-T479 PolarHBondContact O-N 2.9Å; C477-T479 PolarHBondContact SG-OG1 3.38Å; T479-E481 PolarHBondContact O-N 3.41Å; T479-Y500 WeakPolarHBondContact OG1-CB 3.24Å
480T97.2Very high94Very high17 Ų1755.8 Ų55.810%0.10430%0.295CS..  trans-72.6115.7176.5-53.40000109.6Y324 V476 C477 I482 Y500 L501Y324-T480 HydrophobicContact CD2-CG2 4.28Å; Y324-T480 HydrophobicContact CE2-CG2 4.06Å; V476-T480 HydrophobicContact CB-CG2 4.37Å; V476-T480 HydrophobicContact CG1-CG2 4.25Å; C477-T480 PolarHBondContact N-OG1 2.86Å; C477-T480 VanDerWaalsContact O-CB 3.31Å; C477-T480 WeakPolarHBondContact O-CB 3.3Å; C477-T480 PolarHBondContact O-N 3.32Å; C477-T480 PolarHBondContact O-OG1 3.01Å; C477-T480 PolarHBondContact SG-OG1 2.85Å; T480-I482 HydrophobicContact CG2-CD1 4.12Å; T480-I482 HydrophobicContact CG2-CG1 3.9Å; T480-I482 PolarHBondContact O-N 2.95Å; T480-Y500 WeakPolarHBondContact CB-O 3.45Å; T480-Y500 PolarHBondContact OG1-O 3.43Å; T480-L501 HydrophobicContact CG2-CD2 3.92Å
481E96.6Very high93.1Very high84 Ų8458.4 Ų58.439%0.39331%0.308SS..  trans-75.8115.4176.1-175.480.2-157.200110.2Y324 T479 P483 K485Y324-E481 WeakPolarHBondContact CE2-O 3.26Å; Y324-E481 PolarHBondContact OH-O 2.73Å; T479-E481 PolarHBondContact O-N 3.41Å; E481-P483 WeakPolarHBondContact CG-O 3.41Å; E481-K485 HydrophobicContact CG-CG 4.39Å; E481-K485 WeakPolarHBondContact OE1-CD 3.42Å; E481-K485 WeakPolarHBondContact OE1-CE 3.48Å; E481-K485 IonicContact OE1-NZ 2.67Å; E481-K485 PolarHBondContact OE1-NZ 2.59Å; E481-K485 IonicContact OE2-NZ 3.75Å
482I95.5Very high92.8Very high88 Ų8854.8 Ų54.845%0.45130%0.296SS..SBendtrans-130.1116.8178.1-55.1175.2000108.5Y324 Q328 V476 T480Y324-I482 HydrophobicContact CE2-CG1 4.19Å; Q328-I482 HydrophobicContact CG-CD1 4.15Å; V476-I482 HydrophobicContact CB-CD1 4.27Å; V476-I482 HydrophobicContact CG1-CD1 3.77Å; T480-I482 HydrophobicContact CG2-CD1 4.12Å; T480-I482 HydrophobicContact CG2-CG1 3.9Å; T480-I482 PolarHBondContact O-N 2.95Å
483P94.3Very high92.5Very high103 Ų10355 Ų5567%0.66930%0.297SS*.SBendcis-73.7154.6-6.132.6-35.7000112.3E481 K485E481-P483 WeakPolarHBondContact CG-O 3.41Å; P483-K485 PolarHBondContact O-N 2.88Å
484L95Very high92.2Very high17 Ų1751.7 Ų51.79%0.08929%0.285CS..PPolyproline II helixtrans-56138176.3-70.7172.2000112.4Y321 Y324 Y373 Y486 T495 I499Y321-L484 HydrophobicContact CD1-CD1 3.84Å; Y321-L484 HydrophobicContact CE1-CD1 3.83Å; Y324-L484 HydrophobicContact CD1-CD1 3.72Å; Y324-L484 HydrophobicContact CD1-CG 4.29Å; Y324-L484 HydrophobicContact CD2-CD1 4.11Å; Y324-L484 HydrophobicContact CD2-CD2 4.07Å; Y324-L484 HydrophobicContact CD2-CG 4.13Å; Y324-L484 HydrophobicContact CE1-CD1 3.7Å; Y324-L484 HydrophobicContact CE1-CG 3.86Å; Y324-L484 HydrophobicContact CE2-CD1 4.09Å; Y324-L484 HydrophobicContact CE2-CD2 3.78Å; Y324-L484 HydrophobicContact CE2-CG 3.67Å; Y324-L484 HydrophobicContact CG-CD1 3.94Å; Y324-L484 HydrophobicContact CG-CG 4.43Å; Y373-L484 HydrophobicContact CE1-CD1 4.11Å; L484-Y486 HydrophobicContact CB-CE1 4.31Å; L484-T495 HydrophobicContact CD1-CG2 4.22Å; L484-T495 HydrophobicContact CD2-CG2 4.09Å; L484-I499 HydrophobicContact CD1-CD1 4.16Å; L484-I499 HydrophobicContact CD2-CD1 4.45Å; L484-I499 HydrophobicContact CD2-CG1 4.21Å
485K94.2Very high91.9Very high122 Ų12252.1 Ų52.153%0.5329%0.287SS..PPolyproline II helixtrans-93.2132168.4-70.2173.6178.6136.50109.9E481 P483 T495 V496E481-K485 HydrophobicContact CG-CG 4.39Å; E481-K485 WeakPolarHBondContact OE1-CD 3.42Å; E481-K485 WeakPolarHBondContact OE1-CE 3.48Å; E481-K485 IonicContact OE1-NZ 2.67Å; E481-K485 PolarHBondContact OE1-NZ 2.59Å; E481-K485 IonicContact OE2-NZ 3.75Å; P483-K485 PolarHBondContact O-N 2.88Å; K485-T495 CarbonylContact O-C 3Å; K485-T495 VanDerWaalsContact O-CA 3.28Å; K485-T495 WeakPolarHBondContact O-CA 3.28Å; K485-V496 HydrophobicContact CB-CB 4.16Å; K485-V496 HydrophobicContact CB-CG2 4.24Å; K485-V496 PolarHBondContact O-N 2.66Å
486Y94.2Very high91.4Very high63 Ų6355.3 Ų55.325%0.24731%0.306CS..BIsolated β-bridgetrans-101.6142.7-179.5-56.1-71000113.2Y321 Y373 L484 P488 L493 G494 V496Y321-Y486 HydrophobicContact CE1-CE1 4.23Å; Y373-Y486 HydrophobicContact CD1-CE1 4.48Å; Y373-Y486 WeakPolarHBondContact CE1-OH 3.38Å; L484-Y486 HydrophobicContact CB-CE1 4.31Å; Y486-P488 WeakPolarHBondContact O-CD 3.44Å; Y486-L493 HydrophobicContact CD1-CD1 3.48Å; Y486-L493 VanDerWaalsContact CD1-CD1 3.48Å; Y486-L493 HydrophobicContact CD1-CG 3.83Å; Y486-L493 HydrophobicContact CD2-CD1 4.08Å; Y486-L493 HydrophobicContact CE1-CD1 3.77Å; Y486-L493 HydrophobicContact CE1-CD2 4.02Å; Y486-L493 HydrophobicContact CE1-CG 3.81Å; Y486-L493 HydrophobicContact CE2-CD1 4.33Å; Y486-L493 HydrophobicContact CG-CD1 3.64Å; Y486-L493 HydrophobicContact CG-CG 4.48Å; Y486-G494 CarbonylContact C-O 3.56Å; Y486-G494 VanDerWaalsContact CA-O 3.25Å; Y486-G494 WeakPolarHBondContact CA-O 3.36Å; Y486-G494 WeakPolarHBondContact CB-O 3.28Å; Y486-V496 WeakPolarHBondContact O-CG2 3.41Å
487S91.4Very high90.8Very high24 Ų2455 Ų5517%0.16832%0.315CS..  trans-75116-177.6176.60000110.9V51 T489 S490 G494V51-S487 WeakPolarHBondContact CG1-O 3.46Å; S487-T489 PolarHBondContact O-N 2.73Å; S487-T489 PolarHBondContact OG-OG1 3.12Å; S487-S490 PolarHBondContact O-N 3.46Å; S487-G494 PolarHBondContact N-O 3.02Å
488P88.2Confident90.6Very high30 Ų3055.2 Ų55.220%0.19532%0.32CS..THydrogen-bonded Turntrans-67.8-18.9-179.228.2-34.9000112.6R47 K48 R50 Y486R47-P488 WeakPolarHBondContact CA-O 3.49Å; K48-P488 WeakPolarHBondContact O-CG 3.38Å; R50-P488 WeakPolarHBondContact O-CB 3.35Å; Y486-P488 WeakPolarHBondContact O-CD 3.44Å
489T83.6Confident90.7Very high66 Ų6647.3 Ų47.341%0.40528%0.277SS..THydrogen-bonded Turntrans-89.9-15.8-178.153.20000113.7R47 S487R47-T489 PolarHBondContact NH1-O 3.03Å; S487-T489 PolarHBondContact O-N 2.73Å; S487-T489 PolarHBondContact OG-OG1 3.12Å
490S81.9Confident90.8Very high25 Ų2548.2 Ų48.218%0.17527%0.272CS..  trans-69.4142.7179.7-175.40000111.5S487 V492S487-S490 PolarHBondContact O-N 3.46Å; S490-V492 WeakPolarHBondContact CB-O 3.29Å; S490-V492 PolarHBondContact OG-N 2.77Å; S490-V492 PolarHBondContact OG-O 2.92Å
491I76.5Confident90.8Very high71 Ų7147.4 Ų47.436%0.36427%0.267SS..SBendtrans-78.3-35.3176.6-65.2170.1000110.7M52M52-I491 WeakPolarHBondContact CE-O 3.35Å
492V86.8Confident90.8Very high16 Ų1646.5 Ų46.510%0.09726%0.26CS..SBendtrans-101.6167.2172.4-63.60000110E313 L375 S490 G494E313-V492 HydrophobicContact CG-CG2 4.11Å; L375-V492 CarbonylContact O-C 3.47Å; L375-V492 VanDerWaalsContact O-CA 3.28Å; L375-V492 WeakPolarHBondContact O-CA 3.24Å; L375-V492 WeakPolarHBondContact O-CB 3.24Å; S490-V492 WeakPolarHBondContact CB-O 3.29Å; S490-V492 PolarHBondContact OG-N 2.77Å; S490-V492 PolarHBondContact OG-O 2.92Å; V492-G494 PolarHBondContact O-N 3.21Å
493L91.6Very high90.9Very high6 Ų642.5 Ų42.53%0.03124%0.24CC..SBendtrans-63.797.9172.9-172.267.2000110Y321 Y373 L375 Y486Y321-L493 PolarHBondContact OH-O 2.93Å; Y373-L493 HydrophobicContact CD1-CD2 4.16Å; L375-L493 HydrophobicContact CD2-CB 4.4Å; L375-L493 PolarHBondContact O-N 2.79Å; Y486-L493 HydrophobicContact CD1-CD1 3.48Å; Y486-L493 VanDerWaalsContact CD1-CD1 3.48Å; Y486-L493 HydrophobicContact CD1-CG 3.83Å; Y486-L493 HydrophobicContact CD2-CD1 4.08Å; Y486-L493 HydrophobicContact CE1-CD1 3.77Å; Y486-L493 HydrophobicContact CE1-CD2 4.02Å; Y486-L493 HydrophobicContact CE1-CG 3.81Å; Y486-L493 HydrophobicContact CE2-CD1 4.33Å; Y486-L493 HydrophobicContact CG-CD1 3.64Å; Y486-L493 HydrophobicContact CG-CG 4.48Å
494G90.1Very high90.9Very high1 Ų140.2 Ų40.21%0.0122%0.22CC..  trans-121.7153.4178.600000110.9Y321 Y486 S487 V492Y321-G494 WeakPolarHBondContact OH-CA 3.41Å; Y486-G494 CarbonylContact C-O 3.56Å; Y486-G494 VanDerWaalsContact CA-O 3.25Å; Y486-G494 WeakPolarHBondContact CA-O 3.36Å; Y486-G494 WeakPolarHBondContact CB-O 3.28Å; S487-G494 PolarHBondContact N-O 3.02Å; V492-G494 PolarHBondContact O-N 3.21Å
495T91.9Very high90.8Very high10 Ų1044.4 Ų44.46%0.06124%0.235CC..BIsolated β-bridgetrans-79.8152.8178.648.80000113.1Y321 L484 K485 G497 I499Y321-T495 HydrophobicContact CE1-CG2 3.83Å; L484-T495 HydrophobicContact CD1-CG2 4.22Å; L484-T495 HydrophobicContact CD2-CG2 4.09Å; K485-T495 CarbonylContact O-C 3Å; K485-T495 VanDerWaalsContact O-CA 3.28Å; K485-T495 WeakPolarHBondContact O-CA 3.28Å; T495-G497 WeakPolarHBondContact CB-O 3.42Å; T495-G497 PolarHBondContact O-N 2.84Å; T495-G497 PolarHBondContact OG1-O 2.99Å; T495-I499 HydrophobicContact CG2-CD1 4.19Å; T495-I499 HydrophobicContact CG2-CG1 4.07Å
496V87.1Confident90.5Very high90 Ų9044.7 Ų44.755%0.54524%0.241SC..SBendtrans-76.6102.7161.4-179.80000106.6K485 Y486K485-V496 HydrophobicContact CB-CB 4.16Å; K485-V496 HydrophobicContact CB-CG2 4.24Å; K485-V496 PolarHBondContact O-N 2.66Å; Y486-V496 WeakPolarHBondContact O-CG2 3.41Å
497G85.3Confident90.4Very high55 Ų5543.8 Ų43.857%0.56724%0.241SC*.SBendtrans88.3-166.2-171.100000112.9T495T495-G497 WeakPolarHBondContact CB-O 3.42Å; T495-G497 PolarHBondContact O-N 2.84Å; T495-G497 PolarHBondContact OG1-O 2.99Å
498G90.8Very high90.3Very high19 Ų1944.8 Ų44.820%0.19625%0.245CC..  trans-89-179.3176.900000113.5E174E174-G498 WeakPolarHBondContact OE1-CA 3.44Å
499I97.1Very high90.4Very high3 Ų345.7 Ų45.72%0.01525%0.247CC..  trans-109.5107.7168-59.7-173.8000107.1E174 I175 Y321 Y324 L484 T495 L501E174-I499 PolarHBondContact OE1-N 2.83Å; I175-I499 WeakPolarHBondContact CB-O 3.47Å; I175-I499 PolarHBondContact N-O 2.75Å; Y321-I499 HydrophobicContact CD1-CD1 3.79Å; Y321-I499 HydrophobicContact CE1-CD1 3.91Å; Y324-I499 HydrophobicContact CD2-CG2 4.13Å; L484-I499 HydrophobicContact CD1-CD1 4.16Å; L484-I499 HydrophobicContact CD2-CD1 4.45Å; L484-I499 HydrophobicContact CD2-CG1 4.21Å; T495-I499 HydrophobicContact CG2-CD1 4.19Å; T495-I499 HydrophobicContact CG2-CG1 4.07Å; I499-L501 HydrophobicContact CG2-CD1 4.49Å; I499-L501 HydrophobicContact CG2-CD2 4.41Å; I499-L501 HydrophobicContact CG2-CG 4.16Å
500Y97.8Very high90.8Very high102 Ų10244.5 Ų44.540%0.424%0.238SC..EExtended strand (participates in β ladder)trans-95.7124179.3-63.5-92.7000110V172 L173 E174 T479 T480V172-Y500 HydrophobicContact CG1-CD1 4.38Å; L173-Y500 WeakPolarHBondContact O-CA 3.16Å; E174-Y500 HydrophobicContact CB-CD1 3.94Å; E174-Y500 HydrophobicContact CB-CE1 3.6Å; E174-Y500 HydrophobicContact CG-CD1 3.99Å; E174-Y500 HydrophobicContact CG-CD2 4.42Å; E174-Y500 HydrophobicContact CG-CE1 3.49Å; E174-Y500 VanDerWaalsContact CG-CE1 3.49Å; E174-Y500 HydrophobicContact CG-CE2 3.96Å; E174-Y500 HydrophobicContact CG-CG 4.42Å; E174-Y500 VanDerWaalsContact CG-CZ 3.47Å; T479-Y500 WeakPolarHBondContact OG1-CB 3.24Å; T480-Y500 WeakPolarHBondContact CB-O 3.45Å; T480-Y500 PolarHBondContact OG1-O 3.43Å
501L97.8Very high91.4Very high0 Ų045.7 Ų45.70%024%0.242CC..EExtended strand (participates in β ladder)trans-130152.4176.1-60.5179.5000109.9V172 L173 I175 L323 A327 T480 I499V172-L501 WeakPolarHBondContact CA-O 3.27Å; L173-L501 PolarHBondContact N-O 2.85Å; L173-L501 PolarHBondContact O-N 2.71Å; L173-L501 VanDerWaalsContact O-N 3.09Å; I175-L501 HydrophobicContact CD1-CB 4.26Å; I175-L501 HydrophobicContact CG1-CB 3.8Å; I175-L501 HydrophobicContact CG1-CD1 3.85Å; I175-L501 HydrophobicContact CG1-CG 3.83Å; L323-L501 HydrophobicContact CB-CD1 3.96Å; L323-L501 WeakPolarHBondContact O-CD1 3.44Å; A327-L501 HydrophobicContact CB-CD1 3.96Å; A327-L501 HydrophobicContact CB-CD2 3.72Å; A327-L501 HydrophobicContact CB-CG 4.43Å; T480-L501 HydrophobicContact CG2-CD2 3.92Å; I499-L501 HydrophobicContact CG2-CD1 4.49Å; I499-L501 HydrophobicContact CG2-CD2 4.41Å; I499-L501 HydrophobicContact CG2-CG 4.16Å
502R96.7Very high92.4Very high65 Ų6544 Ų4425%0.24523%0.234CC..EExtended strand (participates in β ladder)trans-79.6133.4166.3-178.7174.5-56.8-80-3108.9N169 V474 S475 C477 E504N169-R502 PolarHBondContact O-NH1 3.45Å; V474-R502 CarbonylContact C-O 3.53Å; V474-R502 VanDerWaalsContact CA-O 3.32Å; V474-R502 WeakPolarHBondContact CA-O 3.38Å; S475-R502 PolarHBondContact N-O 3.03Å; S475-R502 PolarHBondContact O-N 3.14Å; C477-R502 HydrophobicContact CB-CB 4.13Å; R502-E504 WeakPolarHBondContact CD-OE1 3.33Å; R502-E504 HydrophobicContact CG-CG 4.23Å
503V97.1Very high92.8Very high4 Ų446 Ų462%0.02424%0.244CC..EExtended strand (participates in β ladder)trans-122.8124.3178.5-172.70000108.2I160 V164 G170 A171 L173 I175 F472 R473 V474I160-V503 HydrophobicContact CG2-CG1 4.3Å; V164-V503 WeakPolarHBondContact CG1-O 3.1Å; V164-V503 HydrophobicContact CG2-CB 4.04Å; V164-V503 HydrophobicContact CG2-CG1 4Å; G170-V503 CarbonylContact C-O 3.52Å; G170-V503 WeakPolarHBondContact CA-O 3.42Å; A171-V503 PolarHBondContact N-O 2.91Å; A171-V503 PolarHBondContact O-N 2.87Å; L173-V503 HydrophobicContact CB-CG2 4.28Å; L173-V503 HydrophobicContact CD1-CB 4.19Å; L173-V503 HydrophobicContact CD1-CG2 3.9Å; L173-V503 HydrophobicContact CG-CB 4.48Å; L173-V503 HydrophobicContact CG-CG2 4.09Å; I175-V503 HydrophobicContact CD1-CG2 3.99Å; F472-V503 HydrophobicContact CB-CG1 3.72Å; F472-V503 HydrophobicContact CD1-CG1 3.77Å; F472-V503 HydrophobicContact CG-CG1 3.9Å; R473-V503 WeakPolarHBondContact O-CA 3.42Å; V474-V503 HydrophobicContact CG1-CG2 4.22Å
504E95Very high92.9Very high56 Ų5649.1 Ų49.126%0.26226%0.26SS..EExtended strand (participates in β ladder)trans-122.7137.3-177.8-72.2166.8-175.300109.5F472 R473 R502F472-E504 CarbonylContact C-O 3.52Å; F472-E504 WeakPolarHBondContact CA-O 3.47Å; F472-E504 WeakPolarHBondContact CB-O 3.2Å; R473-E504 HydrophobicContact CB-CB 4.47Å; R473-E504 PolarHBondContact N-O 3.27Å; R473-E504 PolarHBondContact O-N 2.77Å; R502-E504 WeakPolarHBondContact CD-OE1 3.33Å; R502-E504 HydrophobicContact CG-CG 4.23Å
505R92.3Very high93.1Very high105 Ų10553.1 Ų53.140%0.39628%0.281SS..EExtended strand (participates in β ladder)trans-72.8140.6171.3-63.9-171.7-166.5-179.812.9109.4T161 V164 F472T161-R505 VanDerWaalsContact CG2-NH2 3.32Å; T161-R505 PolarHBondContact O-NH2 3.08Å; V164-R505 HydrophobicContact CG1-CG 4.01Å; V164-R505 PolarHBondContact O-NE 3.19Å; V164-R505 PolarHBondContact O-NH2 3.05Å; F472-R505 HydrophobicContact CD1-CG 4Å; F472-R505 HydrophobicContact CE1-CG 3.73Å
506I88.3Confident93.2Very high128 Ų12857 Ų5766%0.65630%0.301SS*.  trans-109.90174.352166.3000112.1R337 R471 R473R337-I506 VanDerWaalsContact CD-CD1 3.49Å; R471-I506 VanDerWaalsContact C-CG1 3.41Å; R471-I506 VanDerWaalsContact O-CG1 3.28Å; R471-I506 WeakPolarHBondContact O-CG1 3.47Å; R471-I506 PolarHBondContact O-N 3.48Å; R473-I506 HydrophobicContact CB-CG2 3.98Å

Retrieved 506 of 506 residues in 427.4 ms (Link to these results)